PMC8716518__F11 Extracellular vesicles (EVs) isolated from key time points after burn injury induce differential gene expressions, predicted to significantly impact immune functions in macrophages in vitro ENSG00000084092 ENSG00000198846 PMC8165385__F1 Methylene Blue Application to Lessen Pain: Its Analgesic Effect and Mechanism ENSG00000198125 ENSG00000096717 PMC9210989__F3 Significance of PAK4 in signaling and clinicopathology: A review ENSG00000104856 ENSG00000019991 ENSG00000159224 ENSG00000002330 ENSG00000070831 ENSG00000102871 ENSG00000138798 ENSG00000146648 ENSG00000130669 ENSG00000164949 PMC4968117__F1 Epidermal growth factor receptor and its downstream signaling pathway ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC7683543__F5 Canonical pathway enrichment analysis identifies immune response classical complement pathway as the ones most enriched in PVEC co-cultured with NPC ENSG00000203710 ENSG00000168036 ENSG00000244731 PMC7890860__F4 Signalling pathway and key factors which regulated the mitochondrial energy metabolism in MSCs ENSG00000175567 ENSG00000096717 ENSG00000142082 PMC7905242__F4 “瓜蒌-甘草”药对化学成分（）-靶点蛋白（）-信号通路（）网络Chemical components ()-target protein ()-signal pathway () network of "Trichosanthis fructus-Glycyrrhizae radix et rhizoma" drug pair ENSG00000180210 ENSG00000277571 ENSG00000117525 ENSG00000130164 ENSG00000165841 ENSG00000129214 ENSG00000118777 ENSG00000010671 ENSG00000104368 PMC10216619__F4 Possible neurological and mental COVID-19 outcomes related to the angiotensin-converting enzyme 2/Mas/brain-derived neurotrophic factor (ACE2\Mas\BDNF) signaling pathway occupation by SARS-CoV-2 ENSG00000130234 ENSG00000125538 ENSG00000184012 PMC10216619__F2 Adiponectin paradox and its related pathways during COVID-19 infection ENSG00000130234 ENSG00000184012 ENSG00000189403 PMC4456163__F1 Putative Regulatory Factors Associated with Intramuscular Fat Content ENSG00000087250 PMC4714843__F7 Early Regulation of Profibrotic Genes in Primary Human Cardiac Myocytes by Trypanosoma cruzi ENSG00000136158 ENSG00000137834 ENSG00000081041 ENSG00000128342 ENSG00000283060 ENSG00000113525 ENSG00000125968 ENSG00000187678 PMC8400885__F10 Benzoic Acid and Its Hydroxylated Derivatives Suppress Early Blight of Tomato (Alternaria solani) via the Induction of Salicylic Acid Biosynthesis and Enzymatic and Nonenzymatic Antioxidant Defense Machinery PMC8950247__F3 Polymorphisms and Gene-Gene Interaction in AGER/IL6 Pathway Might Be Associated with Diabetic Ischemic Heart Disease ENSG00000169896 ENSG00000242689 ENSG00000109320 ENSG00000143013 ENSG00000033800 ENSG00000173039 ENSG00000189403 ENSG00000168878 PMC8395431__F1 TNFA and Immune Checkpoint Inhibition: Friend or Foe for Lung Cancer? ENSG00000102871 ENSG00000162924 ENSG00000168040 ENSG00000127191 PMC9408851__F3 Function of N-Myc Downstream-Regulated Gene 2 (NDRG2) as a Negative Regulator in Tumor Cell Metastasis ENSG00000168610 ENSG00000165795 PMC11957794__F3 Different types of COL remodeling-mediated signaling pathways ENSG00000122882 ENSG00000168610 ENSG00000079999 PMC8313969__F2 Macrophages, as a Promising Strategy to Targeted Treatment for Colorectal Cancer Metastasis in Tumor Immune Microenvironment ENSG00000066468 ENSG00000108691 ENSG00000198793 ENSG00000168036 ENSG00000168610 ENSG00000146648 PMC4360066__F6 T-cell activation pathway regulating six key activation genes ENSG00000111537 ENSG00000164691 ENSG00000115415 ENSG00000109320 ENSG00000010810 PMC12078210__F4 IL-21 promotes the formation and maintenance of germinal centers and plays a decisive role in the differentiation of GC-derived B cells into plasma cells ENSG00000186716 ENSG00000145321 ENSG00000196092 PMC12078210__F2 Pathways of Allogeneic Antigen Recognition and the Impact of IL-21 on DCs ENSG00000126353 PMC4213195__F5 Schematic model of Wnt- and SHH pathways working interdependently in GBM based upon observations in this study ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC2238877__F4 PharmGKB Irinotecan Pathway ENSG00000172831 ENSG00000114200 ENSG00000109320 ENSG00000118777 ENSG00000042088 ENSG00000023839 ENSG00000262243 PMC6006338__F5 Differential antiviral immunity to Japanese encephalitis virus in developing cortical organoids ENSG00000213928 ENSG00000115415 PMC7946814__F1 Sclerostin: an inhibitor of canonical Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11664622__F1 Hepatitis B virus immune tolerance mechanism ENSG00000163599 PMC3151419__F6 Regulation of the mTOR signaling pathway by insulin and growth factors ENSG00000169047 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC11664622__F2 Pathogenesis of liver cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000171791 ENSG00000128602 ENSG00000137845 ENSG00000124762 PMC3151419__F7 Regulation of mTOR pathway by Sestrins ENSG00000285069 ENSG00000080546 PMC4031321__F1 HIV induction by PKC activators and HDAC and BET inhibitors: NFKB is sequestered in the cytoplasm by IKB ENSG00000136807 ENSG00000141867 PMC7677305__F4 Activation of the cGAS-cGAMP-STING pathway mediates obesity-induced inflammation and metabolic disorders ENSG00000183735 ENSG00000164430 PMC6117983__F4 Platelet hyperreactivity in type 2 diabetes mellitus ENSG00000082175 ENSG00000169047 PMC6222618__F1 Post-squalene cholesterol biosynthetic pathway ENSG00000116133 ENSG00000109929 PMC3677135__F6 The canonical Shh signaling pathway ENSG00000164690 ENSG00000128602 PMC3677135__F7 Wnt signaling pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000112655 ENSG00000168036 PMC3677135__F8 Intracellular mechanisms underlying Wnt-induced axon guidance ENSG00000008300 PMC11780521__F5 Metabolic reprogramming in fibrogenic HSCs activation in chronic liver diseases ENSG00000130164 ENSG00000162337 ENSG00000136869 ENSG00000100219 ENSG00000108821 ENSG00000075239 ENSG00000169174 PMC9209730__F3 New Sights Into Long Non-Coding RNA LINC01133 in Cancer ENSG00000178860 ENSG00000130513 PMC3577986__F6 Gene Network Analysis of Small Molecules with Autoimmune Disease Associated Genes Predicts a Novel Strategy for Drug Efficacy ENSG00000113889 ENSG00000142192 ENSG00000090104 ENSG00000170027 PMC8042693__F11 PPI network ENSG00000248144 PMC3577986__F4 Gene Network Analysis of Small Molecules with Autoimmune Disease Associated Genes Predicts a Novel Strategy for Drug Efficacy ENSG00000111537 ENSG00000170615 ENSG00000179914 ENSG00000119919 ENSG00000138311 ENSG00000237693 ENSG00000168610 PMC9139342__F9 Mediating EGFR-TKI Resistance by VEGF/VEGFR Autocrine Pathway in Non-Small Cell Lung Cancer ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC3577986__F1 Gene Network Analysis of Small Molecules with Autoimmune Disease Associated Genes Predicts a Novel Strategy for Drug Efficacy ENSG00000203747 ENSG00000213918 ENSG00000138378 ENSG00000110395 ENSG00000105397 ENSG00000162924 ENSG00000166278 ENSG00000171791 ENSG00000115661 ENSG00000150637 ENSG00000188389 ENSG00000132170 PMC3677135__F2 Shh and Wnts guide commissural axons in the vertebrate spinal cord ENSG00000164161 ENSG00000144857 ENSG00000164690 ENSG00000128602 PMC5991413__F1 Unsolved mysteries: How does lipid peroxidation cause ferroptosis? ENSG00000167468 ENSG00000111684 PMC3821792__F2 TLR-4 signaling pathway.Notes: TLR-4/MD-2 complex homodimerization activates the MyD88-dependent pathway and TRIF-dependent pathway ENSG00000111537 ENSG00000134070 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC9405250__F11 Polyphenols from Thinned Young Apples: HPLC-HRMS Profile and Evaluation of Their Anti-Oxidant and Anti-Inflammatory Activities by Proteomic Studies ENSG00000127948 ENSG00000156273 ENSG00000079999 PMC8573346__F8 Iguratimod Alleviates Myocardial Ischemia/Reperfusion Injury Through Inhibiting Inflammatory Response Induced by Cardiac Fibroblast Pyroptosis via COX2/NLRP3 Signaling Pathway ENSG00000278718 ENSG00000162711 PMC1134985__F3 Exploring the functions of RNA interference pathway proteins: some functions are more RISCy than others? ENSG00000163624 ENSG00000090402 ENSG00000187446 PMC3779382__F6 Therapeutic modulation of EBV infection and associated signaling pathways ENSG00000186716 ENSG00000198793 PMC11011165__F1 Inappropriate STAT activation in cancer cells ENSG00000291971 ENSG00000186716 ENSG00000146648 PMC8067185__F1 Induction of EMT by targeting EMT-related genes via activation of the growth factor signaling pathway in pancreatic cancer ENSG00000120149 ENSG00000170558 ENSG00000196591 ENSG00000196154 PMC3179879__F5 Abrin (ABR)-triggered apoptosis ENSG00000174429 ENSG00000047936 PMC4041745__F5 Systematic Pathway Enrichment Analysis of a Genome-Wide Association Study on Breast Cancer Survival Reveals an Influence of Genes Involved in Cell Adhesion and Calcium Signaling on the Patients’ Clinical Outcome ENSG00000038382 ENSG00000106683 ENSG00000169291 ENSG00000011422 ENSG00000070831 ENSG00000112715 ENSG00000122194 ENSG00000141968 ENSG00000182541 PMC4041745__F6 Systematic Pathway Enrichment Analysis of a Genome-Wide Association Study on Breast Cancer Survival Reveals an Influence of Genes Involved in Cell Adhesion and Calcium Signaling on the Patients’ Clinical Outcome ENSG00000108557 ENSG00000070831 ENSG00000156299 ENSG00000149269 ENSG00000010810 ENSG00000163914 ENSG00000146648 ENSG00000182541 PMC3779382__F2 EBV-mediated oncogenic signaling pathway activation in EBV-positive diffuse large B-cell lymphoma of the elderly ENSG00000102871 ENSG00000082512 ENSG00000056558 ENSG00000123374 ENSG00000131323 ENSG00000127191 PMC3115623__F5 Major intracellular signal transduction pathways for CRF1 and CRF2 receptors ENSG00000291971 PMC3617635__F6 CLL-induced Rho GTPase signaling defects in T cells that suppress LFA-1 activation signaling and migration and how this is reversible with lenalidomide ENSG00000070831 PMC5884250__F2 Proposed molecular mechanism for maintenance of MSC stemness by cell–cell adhesion through cadherin ENSG00000291971 ENSG00000170558 PMC4041745__F4 Systematic Pathway Enrichment Analysis of a Genome-Wide Association Study on Breast Cancer Survival Reveals an Influence of Genes Involved in Cell Adhesion and Calcium Signaling on the Patients’ Clinical Outcome ENSG00000180210 ENSG00000137672 ENSG00000168398 ENSG00000138741 PMC9126990__F1 Biochemical genesis of enzymatic and non-enzymatic post-translational modifications ENSG00000131473 ENSG00000113790 ENSG00000115419 ENSG00000026103 PMC3419804__F1 Autophagy, Myocardial Protection and the Metabolic Syndrome ENSG00000177169 ENSG00000169047 PMC5710380__F1 Mast cells and their receptors ENSG00000183695 ENSG00000136869 PMC11840356__F1 Mitochondrial Dysfunction and Pathways of Apoptosis in Traumatic Brain Injury (TBI) ENSG00000002330 ENSG00000168040 ENSG00000026103 PMC7998465__F7 Molecular regulatory mechanism underlying UA’s anticancer activity in NSCLC cells, and UA’s inhibition of the EGFR/JAK2/STAT3 signaling pathway and PD-L1 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC4284625__F1 Genetic pathways, prevention, and treatment of sporadic colorectal cancer ENSG00000157764 ENSG00000134982 PMC7716721__F4 SFN-induced ferroptosis pathway ENSG00000151012 ENSG00000175793 ENSG00000167468 PMC12185281__F3 Pathophysiological mechanisms of insulin resistance in the vasculature ENSG00000005882 PMC4879750__F1 TGFB signaling in fibroblasts ENSG00000086991 PMC6087706__F2 Signaling cascades for YAP/TAZ regulation ENSG00000291971 ENSG00000197905 ENSG00000168036 ENSG00000114978 ENSG00000007866 ENSG00000150457 ENSG00000144791 ENSG00000131023 ENSG00000074219 PMC4916901__F1 Link between DNA damage and transcription, and pathway of DSB-induced transcriptional repression ENSG00000149311 ENSG00000198901 ENSG00000163961 ENSG00000112130 PMC6366666__F1 TRAIL pathway targeting therapeutics ENSG00000168040 PMC6211039__F2 Unfolded protein response pathways ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC8233907__F9 Chalcones as Promising Antitumor Agents by Targeting the p53 Pathway: An Overview and New Insights in Drug-Likeness ENSG00000134057 ENSG00000135446 ENSG00000026103 PMC6060268__F4 Overlapping actions of metformin and rapamycin ENSG00000198793 PMC8858883__AF1 Puerarin specifically disrupts osteoclast activation via blocking integrinB3 Pyk2/Src/Cbl signaling pathway ENSG00000291971 ENSG00000177606 PMC4465126__F7 Proposed mechanism by which hyperaldosteronism decreases pulmonary endothelial eNOS activation and nitric oxide (NO•) generation in PAH ENSG00000086991 ENSG00000179142 PMC8307022__F1 Curcumin: Modulator of Key Molecular Signaling Pathways in Hormone-Independent Breast Cancer ENSG00000168036 PMC3814228__F1 Schematic diagram of the adiponectin-AMPK pathway in glomerular cells ENSG00000086991 ENSG00000159346 ENSG00000285070 PMC5522315__F3 Epithelial-to-mesenchymal transition in the development of endometriosis ENSG00000134982 ENSG00000168036 PMC3575670__F5 Precursor of myostatin is promyostatin and consists of a propeptide that binds to myostatin noncovalently to form an inactive complex PMC10917964__F3 Schematic diagram illustrating the promotion of bone formation by incorporating Sr2+ on the surface of titanium-based materials ENSG00000168036 ENSG00000100985 ENSG00000167182 ENSG00000131196 PMC5069446__F2 Nutrients-mTOR-miRNA signaling in skeletal myogenesis ENSG00000169047 ENSG00000113360 ENSG00000125968 PMC6210148__F1 Topoisomerase 1 reaction and inhibitors ENSG00000143799 ENSG00000042088 ENSG00000138385 PMC5954027__F1 Selective and non-selective autophagy in CD4 T cells upon T cell receptor (TCR) activation ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000198793 PMC6186311__F5 Beneficial effect of RC on hepatic glucose and lipid metabolism signalling pathways ENSG00000042832 PMC11626780__F5 Immunosuppressive pathways involving tryptophan ENSG00000180773 ENSG00000262635 PMC11626780__F6 Intracellular metabolic pathways of BCAAs and the mTORC1 signaling pathway ENSG00000177169 ENSG00000060982 ENSG00000100227 ENSG00000112561 ENSG00000108443 PMC11626780__F3 Glutamine interconversions and metabolic pathways ENSG00000135069 ENSG00000100033 ENSG00000146733 ENSG00000070669 PMC11626780__F4 Urea synthesis pathway involving arginine and PRMT-mediated FLT3 arginine methylation ENSG00000122025 ENSG00000178445 ENSG00000107077 PMC4681406__F7 Adiponectin Regulates Bone Marrow Mesenchymal Stem Cell Niche through a Unique Signal Transduction Pathway - An Approach for Treating Bone Disease in Diabetes ENSG00000178860 ENSG00000170365 ENSG00000157500 ENSG00000159346 ENSG00000100985 PMC7068130__F8 Molecular Mechanism of Loss of Function of TLR9 Might Play a Major Role for NPC Susceptibility in Specific Ethnic Groups of NE IndiaSome populations, called “mongoloids,” show a significantly higher incidence for NPC ENSG00000239732 ENSG00000188313 ENSG00000142611 PMC2691147__F1 Hh signalling—a simplified model ENSG00000128602 PMC11726638__F9 Diagram encapsulates our hypothesis that cytidine/uridine monophosphate kinase 2 (CMPK2) promotes the progression of allergic rhinitis by activating the NLRP3 inflammasome via the mitochondrial DNA (mtDNA)‐STING signalling pathway ENSG00000162711 ENSG00000164430 ENSG00000134326 PMC3142679__F1 Virus reactivation: a panoramic view in human infections ENSG00000136997 PMC3095455__F1 Schematic representation of the apoptosis signaling pathway that indicates existence of three distinct signaling modules in the apoptotic intrinsic pathway PMC8088080__F6 Unraveling the molecular crosstalk between Atherosclerosis and COVID-19 comorbidity ENSG00000081041 ENSG00000163734 ENSG00000169429 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC3887612__F5 Tau signaling cascade in LPA induced neurite retraction in differentiated Neuro2a cells ENSG00000163914 ENSG00000198670 PMC5472377__F6 Pathway alterations diagram integrating gene mutations and copy number alterations to identify pathways altered in UC- and CD-associated CAC ENSG00000124102 ENSG00000157764 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000149311 ENSG00000066468 ENSG00000135446 ENSG00000136997 ENSG00000105810 ENSG00000077782 ENSG00000139687 ENSG00000146648 ENSG00000196712 ENSG00000109670 PMC3840609__F5 Gonadotropin-releasing hormone (GnRH) signaling pathway containing genes that are represented in the Partial Correlation Information Theory (PCIT) network “growth at the onset of puberty” ENSG00000087245 ENSG00000070831 ENSG00000146648 PMC5665037__F2 Involvement of lncRNAs in the “adenoma-carcinoma sequence”, multi-step model of CRC pathogenesis ENSG00000169554 ENSG00000165119 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC3425519__F2 Intracellular vascular endothelial growth factor (VEGF) signal transduction pathway ENSG00000157764 ENSG00000198793 PMC4417610__F2 Summary of the HGF/c-Met signaling pathway ENSG00000019991 ENSG00000291971 ENSG00000168610 PMC12043450__F4 Signaling pathways associated with GH treatment for DOR ENSG00000112964 ENSG00000148400 ENSG00000198793 ENSG00000142082 PMC6512360__F9 The type I immune response in M ENSG00000140968 ENSG00000077984 ENSG00000172543 ENSG00000027697 ENSG00000113088 ENSG00000237693 ENSG00000166670 ENSG00000125347 ENSG00000276561 ENSG00000007171 ENSG00000143387 ENSG00000291983 ENSG00000111537 ENSG00000115415 PMC8546337__F1 Targeting DNA Repair Response Promotes Immunotherapy in Ovarian Cancer: Rationale and Clinical Application ENSG00000169245 ENSG00000183735 ENSG00000164430 PMC5578105__F1 Ubiquitin signaling in both sub-pathways of nucleotide excision repair (NER), global genomic (GG-) and Transcription coupled NER (TC-NER), and double-strand break (DSB) repair ENSG00000149311 ENSG00000158290 ENSG00000163961 ENSG00000069869 ENSG00000134574 ENSG00000100387 ENSG00000121481 ENSG00000163945 ENSG00000167986 ENSG00000139842 ENSG00000112130 PMC11721126__F1 The development of SARS-CoV-2 induced osteoarthritis ENSG00000136160 ENSG00000151617 PMC7280757__F3 Complement Membrane Attack Complex ENSG00000104856 ENSG00000278718 ENSG00000162711 ENSG00000173039 ENSG00000162692 ENSG00000100711 ENSG00000115009 PMC5673544__F1 Tandem repeat variation near the HIC1 promoter predicts outcome of oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer ENSG00000012061 ENSG00000096717 ENSG00000136936 PMC4657330__F8 Rac1 activation and Wnt synergistically enhance Beta-catenin transactivation in the canonical Wnt pathway ENSG00000134982 PMC9453822__F2 Dietary polyphenols on cancer cell pyroptosis and the tumor immune microenvironment ENSG00000102962 ENSG00000107562 ENSG00000168610 PMC4081676__F1 Protective role and partial mechanism of peroxisome proliferator-activated receptor A in alcoholic liver disease ENSG00000135218 ENSG00000105329 ENSG00000105550 ENSG00000175567 ENSG00000096717 PMC7556029__F3 Molecular mechanisms of IL-36R induced tissue fibrosis ENSG00000162711 ENSG00000108691 ENSG00000111537 ENSG00000163739 ENSG00000172936 PMC10532080__F8 Knockdown of BAP31 Downregulates Galectin-3 to Inhibit the Wnt/Beta-Catenin Signaling Pathway to Modulate 5-FU Chemosensitivity and Cancer Stemness in Colorectal Cancer ENSG00000168036 PMC2917731__F1 Intracellular signaling of FIP1L1/PDGFRA+ (F/P) cells ENSG00000183625 PMC7522025__F1 Schematics of spiralian embryo, TGFB superfamily cassette and larval Capitella phenotypes ENSG00000170365 ENSG00000156574 PMC5642700__F1 Systems biology analysis of longitudinal functional response of endothelial cells to shear stress ENSG00000109320 ENSG00000086991 ENSG00000196591 ENSG00000129355 ENSG00000117707 ENSG00000277273 ENSG00000118971 ENSG00000164294 ENSG00000134480 ENSG00000135446 ENSG00000167468 ENSG00000123374 ENSG00000162692 PMC3325226__F3 A Genome-Wide Association Study Identifies UGT1A1 as a Regulator of Serum Cell-Free DNA in Young Adults: The Cardiovascular Risk in Young Finns Study ENSG00000109819 ENSG00000150782 ENSG00000136997 ENSG00000173039 ENSG00000189403 ENSG00000136869 ENSG00000106546 PMC8819670__F1 Hippo pathway consists of distinct oncogenic and tumour suppressive modules ENSG00000186575 ENSG00000197905 ENSG00000114978 ENSG00000198670 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC8819670__F2 YAP/TAZ fusion partners and associated cancers ENSG00000171735 ENSG00000291987 ENSG00000184384 PMC5818424__F7 Hypothetical model for the pathogenesis of glucose intolerance and insulin resistance in TRIM31−/− mice ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC3564490__F3 Proposed alternative pathway of feto-placental androgen synthesis from 17-hydroxypregnenolone ENSG00000277893 ENSG00000203859 ENSG00000127948 PMC3109867__F1 Insulin/iGF-1 signaling pathway is conserved across phylogeny ENSG00000118515 PMC9525429__F1 Pattern to Link Adenosine Signaling, Circadian System, and Potential Final Common Pathway in the Pathogenesis of Major Depressive Disorder ENSG00000132326 ENSG00000179094 PMC5040753__F7 Proposed mechanism of mechanical stretch-induced VSMC hypertrophy demonstrates that the RhoA/ROCK pathway activation, calcineurin activation, NFAT nuclear translocation, and leptin synthesis are involved in this process ENSG00000163914 PMC2863124__F1 DNA damage and replication checkpoints in various organisms ENSG00000149311 ENSG00000163624 PMC5294813__F3 Functional network of the interferon signaling pathway by IPA ENSG00000213928 ENSG00000111537 ENSG00000033800 ENSG00000125347 PMC9132047__F9 Study on the Mechanism of Sancao Tiaowei Decoction in the Treatment of MNNG-Induced Precancerous Lesions of Gastric Carcinoma Through Hedgehog Signaling Pathway ENSG00000198793 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 ENSG00000146648 PMC4733656__F5 The Elizabeth River Story: A Case Study in Evolutionary Toxicology ENSG00000106546 PMC6482218__F1 The role of molecular genetic markers in cellular stress response ENSG00000157514 ENSG00000165471 PMC4947211__F1 Schematic presentation of gene network implicated in TLR signaling pathway ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC3642686__F4 Schematic description of the MSR ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 ENSG00000276561 PMC2258669__F3 Enzymatic reactions and assays ENSG00000261701 PMC6202076__F0 Aspirin promotes apoptosis and inhibits proliferation by blocking G0/G1 into S phase in rheumatoid arthritis fibroblast-like synoviocytes via downregulation of JAK/STAT3 and NFKB signaling pathway ENSG00000104365 ENSG00000005339 ENSG00000100906 ENSG00000109320 ENSG00000136997 ENSG00000173039 ENSG00000123374 PMC2258669__F1 Genomic and functional context of glycerate kinase enzymes in bacteria ENSG00000261701 ENSG00000203685 PMC5330810__F1 Inference of Cancer Mechanisms through Computational Systems Analysis ENSG00000196839 ENSG00000137198 ENSG00000198931 PMC3997009__F1 Routes of presentation of viral peptides on DCs PMC8012550__F4 Genome-Wide Association Identifies Risk Pathways for SAPHO Syndrome ENSG00000140992 ENSG00000105550 ENSG00000113525 ENSG00000104365 ENSG00000169896 ENSG00000176014 ENSG00000027697 ENSG00000116701 ENSG00000164171 ENSG00000153317 ENSG00000274145 ENSG00000273991 ENSG00000160691 ENSG00000143387 ENSG00000120910 ENSG00000149534 ENSG00000063176 ENSG00000176884 ENSG00000072694 ENSG00000078053 ENSG00000067606 ENSG00000163131 ENSG00000115020 ENSG00000184371 ENSG00000188130 ENSG00000083799 ENSG00000171608 ENSG00000108774 ENSG00000143882 ENSG00000090659 PMC5642700__F4 Higher-resolution version of with gene target names visible ENSG00000104884 ENSG00000110721 ENSG00000105835 ENSG00000058085 ENSG00000178999 ENSG00000163739 ENSG00000120875 ENSG00000148926 ENSG00000122877 ENSG00000127528 ENSG00000088256 ENSG00000162772 ENSG00000147854 ENSG00000112715 ENSG00000145113 ENSG00000136826 ENSG00000291944 ENSG00000108578 ENSG00000245848 ENSG00000100290 ENSG00000134321 ENSG00000213658 ENSG00000038427 ENSG00000141101 ENSG00000150907 ENSG00000100979 ENSG00000164400 ENSG00000086991 ENSG00000197905 ENSG00000168610 ENSG00000143387 ENSG00000010810 ENSG00000177606 ENSG00000136936 PMC4887335__F1 Linking Pathogenic Mechanisms of Alcoholic Liver Disease With Clinical Phenotypes ENSG00000102871 ENSG00000157625 ENSG00000083799 ENSG00000168040 ENSG00000168404 PMC5617345__F1 IGF-1R/AKT pathway determines cell fate in response to p53 ENSG00000159335 ENSG00000140464 ENSG00000140443 PMC5617345__F2 IGF-1R/AKT pathway determines cell fate in response to p53 ENSG00000140443 PMC5617345__F3 IGF-1R/AKT pathway determines cell fate in response to p53 ENSG00000140443 PMC7404121__F2 Synergistic regulation mechanisms of leaf angle by phytohormones in rice ENSG00000062485 PMC4891268__F2 Cell-cycle entry regulated by a network of protein regulators ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC4466452__F1 Identified molecular targets involved in ELFEF-induced enhancement of adult hippocampal neurogenesis and osteogenesis ENSG00000178860 ENSG00000168036 PMC6099685__F7 The potential pathway underlying the anticancer activity of CK in human HCC cells ENSG00000144895 ENSG00000168610 PMC2814453__F1 Coupling between Akt-mediated cellular energy metabolism, cell survival and proliferation PMC8538975__F4 Transcriptome Analysis for Genes Associated with Small Ruminant Lentiviruses Infection in Goats of Carpathian Breed ENSG00000023445 ENSG00000104899 ENSG00000159128 ENSG00000154589 ENSG00000119535 ENSG00000137275 ENSG00000115590 ENSG00000184451 ENSG00000108342 ENSG00000027697 ENSG00000163736 ENSG00000292363 ENSG00000243509 ENSG00000127191 ENSG00000127666 ENSG00000150782 ENSG00000111537 ENSG00000136869 ENSG00000164342 PMC7677787__F2 Lysosomes function as an intracellular signal transduction platform ENSG00000110395 PMC7432591__F2 Major signalling pathways associated with sarcopenia and peripheral arterial disease (PAD) ENSG00000198793 ENSG00000168610 ENSG00000132693 PMC3205276__F1 Biosynthetic pathway of sphingolipids consisting of free long chain bases (top row), which are N-acylated by several CerS enzymes to form dihydroceramides (upper row of octagons) ENSG00000139624 ENSG00000100422 ENSG00000223802 ENSG00000069482 ENSG00000154227 ENSG00000102172 ENSG00000143418 PMC3323831__F1 TLR signalling ENSG00000174125 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000168040 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC8212127__F2 Insulin-Like Growth Factor Pathway and the Thyroid ENSG00000124102 ENSG00000169047 ENSG00000133124 PMC8212127__F3 Insulin-Like Growth Factor Pathway and the Thyroid ENSG00000169047 ENSG00000133124 PMC3965270__F8 Integration of L-R Pitx2 transcription and Wnt signaling drives asymmetric gut morphogenesis via Daam2 ENSG00000170558 ENSG00000156574 ENSG00000146122 ENSG00000164093 PMC8212127__F4 Insulin-Like Growth Factor Pathway and the Thyroid ENSG00000174059 PMC8866957__F2 Glimpse of Programmed Cell Death Among Bacteria, Animals, and Plants ENSG00000167468 ENSG00000185129 ENSG00000285379 ENSG00000127948 PMC3421022__F1 The prolactin signaling network in NetSlim ENSG00000166794 ENSG00000120833 ENSG00000033327 ENSG00000291603 ENSG00000198053 ENSG00000135439 ENSG00000291971 ENSG00000050748 ENSG00000169047 ENSG00000114737 ENSG00000198793 ENSG00000115904 ENSG00000150093 ENSG00000105647 ENSG00000169032 ENSG00000121879 ENSG00000164305 ENSG00000089159 ENSG00000149269 ENSG00000136997 ENSG00000170027 ENSG00000109320 ENSG00000173039 ENSG00000007171 ENSG00000160691 ENSG00000110395 ENSG00000115415 ENSG00000177606 ENSG00000135605 ENSG00000113494 PMC5597488__F5 Cognitive impairment and gene expression alterations in a rodent model of binge eating disorder ENSG00000276825 ENSG00000164879 ENSG00000184845 ENSG00000149295 PMC6295076__F7 Hypothesied pathway showing the inhibitory mechanism of cyclin G2 on Wnt/Beta-catenin signaling through Dpr1 ENSG00000138764 ENSG00000134982 ENSG00000168036 PMC2659402__F3 Interleukin-31 acts through three signaling pathways: Jak/STAT pathway, PI3K/AKT pathway and MAPK pathway ENSG00000145623 ENSG00000168610 PMC3418163__F1 The two enzymatic pathways generating inorganic phosphate (Pi) as a result of LPA degradation ENSG00000198670 PMC9436575__F6 Preventive Electroacupuncture Alleviates Oxidative Stress and Inflammation via Keap1/Nrf2/HO-1 Pathway in Rats with Cyclophosphamide-Induced Premature Ovarian Insufficiency ENSG00000178573 ENSG00000079999 PMC8260517__F2 Anti-carcinogenic effects of exercise-conditioned human serum: evidence, relevance and opportunities ENSG00000198793 ENSG00000150457 ENSG00000131023 PMC5559826__F2 Downregulated genes involved in the insulin signaling pathway in response to the sugar-only diet ENSG00000002330 ENSG00000133116 ENSG00000127948 ENSG00000026103 PMC5378352__F6 All-trans retinoic acid suppresses the angiopoietin-Tie2 pathway and inhibits angiogenesis and metastasis in esophageal squamous cell carcinoma ENSG00000128052 ENSG00000171791 PMC6406849__F3 LRRFIP1/GCF2 binds to exogenous and endogenous nucleic acids and activates type 1 interferon and pro-inflammatory cytokine responses ENSG00000168036 ENSG00000172936 PMC8012063__F4 Status-dependent regulation of Kyoto Encyclopedia of Genes and Genomes pathway hsa050160 Alzheimer’s disease at the cross-tissue level ENSG00000132906 ENSG00000084093 ENSG00000142192 ENSG00000002330 ENSG00000168040 ENSG00000164305 ENSG00000291983 ENSG00000130699 ENSG00000197386 ENSG00000185591 ENSG00000120868 ENSG00000119912 ENSG00000169375 ENSG00000164087 ENSG00000101425 PMC4555477__F1 Some sphingolipid fundamentals ENSG00000100422 PMC4411553__F4 Current Antiplatelet Treatment Strategy in Patients with Diabetes Mellitus ENSG00000115008 ENSG00000259207 ENSG00000005961 PMC4580488__F10 A schematic diagram showing the proposed signaling pathway underlying the regulation of ovarian cancer progression by HBEGF/EGFR/YAP/HBEGF and NRG1/ERBB3/YAP/NRG1positive feedback autocrine loops ENSG00000065361 ENSG00000113070 ENSG00000158458 ENSG00000146648 PMC5636111__F4 Novel network analysis approach reveals DNA damage, oxidative stress and calcium/cAMP homeostasis-associated biomarkers in frontotemporal dementia ENSG00000120910 ENSG00000005339 ENSG00000177606 ENSG00000174804 ENSG00000165059 ENSG00000168036 ENSG00000143933 ENSG00000182621 ENSG00000277641 ENSG00000146648 ENSG00000137841 PMC5636111__F5 Novel network analysis approach reveals DNA damage, oxidative stress and calcium/cAMP homeostasis-associated biomarkers in frontotemporal dementia ENSG00000115008 ENSG00000070831 ENSG00000165059 ENSG00000121879 ENSG00000145391 ENSG00000103942 ENSG00000065135 ENSG00000113262 ENSG00000117020 ENSG00000185386 ENSG00000102466 ENSG00000243708 ENSG00000034713 ENSG00000150907 ENSG00000175104 PMC5094186__F1 (1) Nicotine binds to the nicotinic acetylcholine receptor, causing a conformational change that opens the receptor's ion channel and allowing entry of Ca2+ and Na+ ENSG00000291971 ENSG00000138798 ENSG00000198793 PMC10218397__F9 TASE and thymol supplementation in neuronal differentiation and outgrowth effect ENSG00000124357 PMC9561135__F10 Gut-lung axis: Gut microbiota changes associated with pulmonary fibrosis in mouse models induced by bleomycin ENSG00000291748 ENSG00000197299 ENSG00000108821 PMC5746105__F17 Pathogenesis of diclofenac induced immunoallergic hepatitis in a canine model of liver injury ENSG00000188641 ENSG00000081181 ENSG00000157404 ENSG00000126562 ENSG00000130643 ENSG00000110799 ENSG00000138798 ENSG00000154639 ENSG00000072274 ENSG00000060138 ENSG00000169710 ENSG00000120885 ENSG00000038002 ENSG00000102678 ENSG00000230034 ENSG00000145088 ENSG00000183765 ENSG00000011422 ENSG00000133116 ENSG00000100906 ENSG00000086991 ENSG00000107611 ENSG00000112149 ENSG00000083799 ENSG00000130175 ENSG00000168237 ENSG00000116761 ENSG00000115009 ENSG00000164949 ENSG00000084774 PMC3660250__F8 Molecular Mechanisms of Environmental Enrichment: Impairments in Akt/GSK3B, Neurotrophin-3 and CREB Signaling ENSG00000122194 ENSG00000140443 PMC3807000__F2 Autophagy-related common pathway in neurodevelopmental disorders ENSG00000198793 ENSG00000196712 PMC3834144__F8 Schematic summary of OPRM1 differential signal pathways upon acute and chronic morphine administration ENSG00000112038 ENSG00000291971 PMC9040700__F2 High-mobility group box 1 (HMGB1) in COVID-19: extrapolation of dangerous liaisons ENSG00000162711 ENSG00000115415 ENSG00000130234 PMC9040700__F1 High-mobility group box 1 (HMGB1) in COVID-19: extrapolation of dangerous liaisons ENSG00000198793 ENSG00000189403 ENSG00000172936 ENSG00000136869 PMC8518784__F9 Curcumin analog GL63 inhibits the malignant behaviors of hepatocellular carcinoma by inactivating the JAK2/STAT3 signaling pathway via the circular RNA zinc finger protein 83/microRNA‐324‐5p/cyclin‐dependent kinase 16 axis ENSG00000168610 PMC11212332__F7 Characterisation of sRNAs enriched in outer membrane vesicles of pathogenic Flavobacterium psychrophilum causing Bacterial Cold Water Disease in rainbow trout ENSG00000102189 PMC3616967__F4 Proposed model for iAs-induced birth defects via the GR pathway ENSG00000134086 ENSG00000100906 ENSG00000173039 ENSG00000168036 ENSG00000171791 ENSG00000168610 ENSG00000164305 ENSG00000139687 ENSG00000089159 ENSG00000007171 ENSG00000026103 PMC7222031__F2 PVR’s role in immunomodulation ENSG00000130202 ENSG00000153283 ENSG00000181847 PMC2810629__F1 Tale of Transforming Growth FactorB (TGFB) Signaling: A Soigné Enigma ENSG00000198742 ENSG00000175104 PMC5746105__F16 Pathogenesis of diclofenac induced immunoallergic hepatitis in a canine model of liver injury ENSG00000110799 ENSG00000171791 ENSG00000070669 ENSG00000153879 ENSG00000197977 ENSG00000117335 ENSG00000140284 ENSG00000005187 ENSG00000160293 ENSG00000292332 ENSG00000123983 ENSG00000135919 ENSG00000062485 ENSG00000162552 ENSG00000177575 ENSG00000262785 ENSG00000159128 ENSG00000113600 ENSG00000112964 ENSG00000158234 ENSG00000120915 ENSG00000079257 ENSG00000103569 ENSG00000105697 ENSG00000103150 ENSG00000285250 ENSG00000150787 ENSG00000132356 ENSG00000023909 ENSG00000167780 ENSG00000157131 ENSG00000160752 ENSG00000167107 ENSG00000113905 ENSG00000069869 ENSG00000136960 ENSG00000173992 ENSG00000138823 ENSG00000244038 ENSG00000123609 ENSG00000175899 ENSG00000115361 ENSG00000085871 ENSG00000116690 ENSG00000079435 ENSG00000276838 ENSG00000108433 ENSG00000100196 ENSG00000107562 ENSG00000113790 ENSG00000285070 ENSG00000083799 ENSG00000130175 ENSG00000023839 PMC10379122__F1 Unravelling the Role of P300 and TMPRSS2 in Prostate Cancer: A Literature Review ENSG00000157554 ENSG00000129214 ENSG00000184012 PMC7287266__F1 Retinal Degeneration Caused by Rod-Specific Dhdds Ablation Occurs without Concomitant Inhibition of Protein N-Glycosylation ENSG00000000419 ENSG00000110921 ENSG00000112972 ENSG00000153989 ENSG00000172893 ENSG00000172269 ENSG00000197429 ENSG00000113161 ENSG00000120697 ENSG00000117682 ENSG00000120437 ENSG00000167508 ENSG00000128039 ENSG00000160752 ENSG00000116133 ENSG00000075239 PMC4147692__F3 Apoptosis induction by the HIV-1 envelope protein at the cell surface ENSG00000198793 ENSG00000121966 PMC9205467__F1 Ferroptosis in Chronic Liver Diseases: Opportunities and Challenges ENSG00000168003 ENSG00000186575 ENSG00000151012 ENSG00000196839 ENSG00000167468 ENSG00000136381 ENSG00000079999 PMC4147692__F1 Involvement of HIV proteins in intrinsic apoptotic pathways: The viral proteins are marked in yellow ENSG00000149311 ENSG00000175054 ENSG00000002330 ENSG00000120868 ENSG00000026103 PMC8524328__F4 Exploration of the existing and candidate crosstalk between the diagrams of the COVID‐19 Disease Map ENSG00000105664 ENSG00000088888 ENSG00000103490 ENSG00000078747 ENSG00000148798 ENSG00000177606 ENSG00000136997 ENSG00000173039 PMC8524328__F5 Interferon type I signalling pathway diagram of the COVID‐19 Disease Map integrated with TF activity derived from transcriptomics data after SARS‐CoV‐2 infection ENSG00000148798 ENSG00000263528 ENSG00000177606 ENSG00000173039 PMC10603981__F1 Signaling pathways involved in ferroptosis ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000284099 ENSG00000169710 ENSG00000176046 PMC7067901__F2 Top three molecular networks identified by Ingenuity Pathway Analysis: (A) Network 1 ENSG00000007944 ENSG00000163681 ENSG00000104447 ENSG00000151914 ENSG00000146463 ENSG00000127337 ENSG00000196367 PMC10603981__F2 Necroptosis signaling pathways ENSG00000143799 ENSG00000124256 ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 ENSG00000164342 ENSG00000026103 PMC3290617__F1 Decrease of miR-146b-5p in Monocytes during Obesity Is Associated with Loss of the Anti-Inflammatory but Not Insulin Signaling Action of Adiponectin ENSG00000171105 ENSG00000169047 ENSG00000175104 ENSG00000184216 PMC5145761__F3 Displays canonical BMP pathway identified through Ingenuity Pathway Analysis (IPA) ENSG00000170365 ENSG00000037965 ENSG00000152495 ENSG00000115297 ENSG00000183072 ENSG00000198742 ENSG00000183691 ENSG00000134363 ENSG00000164093 PMC3372896__F1 Central role of Beta-catenin in Wnt signaling and the cadherin complex ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000167074 PMC5145761__F1 Displays canonical IL-1 signaling pathway identified through Ingenuity Pathway Analysis (IPA) ENSG00000177606 ENSG00000132478 ENSG00000172936 ENSG00000130159 ENSG00000175104 PMC7425198__F6 Effective Method for Accurate and Sensitive Quantitation of Rapid Changes of Newly Synthesized Proteins ENSG00000280831 ENSG00000111581 ENSG00000117000 ENSG00000124789 ENSG00000030066 ENSG00000086589 ENSG00000033011 ENSG00000126746 ENSG00000122877 ENSG00000089157 ENSG00000108654 ENSG00000125538 ENSG00000173039 ENSG00000092199 ENSG00000073756 ENSG00000147274 ENSG00000104723 ENSG00000115875 ENSG00000171566 ENSG00000065978 ENSG00000142541 ENSG00000174748 ENSG00000109475 ENSG00000125844 ENSG00000087365 ENSG00000163527 ENSG00000188529 ENSG00000110713 ENSG00000106554 ENSG00000130175 ENSG00000105127 ENSG00000069345 ENSG00000090520 ENSG00000115009 ENSG00000132341 PMC8476871__F1 NFKB Pathway: Modulation by Entamoeba histolytica and Other Protozoan Parasites ENSG00000104856 ENSG00000102871 ENSG00000173039 ENSG00000172936 ENSG00000111321 ENSG00000168040 ENSG00000175104 PMC8476871__F2 NFKB Pathway: Modulation by Entamoeba histolytica and Other Protozoan Parasites ENSG00000174125 ENSG00000239732 ENSG00000069482 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC9231801__F2 Three stages of immunological pathway leading to mortality in COVID-19: Stage I (Initiation), with early induction of predominant chemokines upon SARS-CoV-2 infection and viral sepsis ENSG00000115008 ENSG00000108691 ENSG00000121807 PMC4487446__F7 Scheme illustrating the signaling pathway involved in the production of chemokines and cytokines induced by prostaglandin F2A (PGF2A) ENSG00000108691 ENSG00000125538 ENSG00000169429 PMC4203832__F4 Whole Proteome Analysis of Mouse Lymph Nodes in Cutaneous Anthrax ENSG00000070831 ENSG00000177606 ENSG00000136997 ENSG00000105697 ENSG00000132478 ENSG00000173327 PMC5336598__F1 Role of the unfolded protein response (UPR) in cancer ENSG00000128272 ENSG00000144895 PMC4741987__F8 ZNF32 protects against oxidative stress-induced apoptosis by modulating C1QBP transcription ENSG00000185591 ENSG00000169740 ENSG00000108561 PMC2631600__F1 The HMGCR pathway ENSG00000172893 ENSG00000109929 ENSG00000113161 PMC6721423__F1 PTEN-mediated control of cancer stem cells (CSCs) hallmarks ENSG00000009709 ENSG00000168283 ENSG00000198793 ENSG00000196154 ENSG00000168610 ENSG00000121966 PMC8809122__F9 Epigallocatechin gallate enhances human lens epithelial cell survival after UVB irradiation via the mitochondrial signaling pathway PMC8471358__F1 Ketogenic Diets in Pancreatic Cancer and Associated Cachexia: Cellular Mechanisms and Clinical Perspectives ENSG00000198793 ENSG00000136869 ENSG00000168610 ENSG00000140443 PMC3867867__F3 Genetic determination of testes in Japanese medaka fish, chicken, and mouse ENSG00000162552 ENSG00000104899 ENSG00000186766 ENSG00000125398 ENSG00000137090 ENSG00000102678 PMC4104517__F2 Cell Death and Survival Through the Endoplasmic Reticulum-Mitochondrial Axis ENSG00000004455 ENSG00000116688 PMC5882778__F2 Systemic metabolic cues with Kisspeptin, orexigenic, and anorexigenic neurons ENSG00000173599 ENSG00000115138 PMC5971270__F5 IPA identified “LXR/RXR activation” as the canonical pathway in the ESPs of TC-1 cells with the highest predicted potential/significance affected by the treatment with caerin 1.9, predicted based on label-free quantitation ENSG00000135218 ENSG00000154589 ENSG00000172350 PMC9083176__F1 Brain delivering RNA-based therapeutic strategies by targeting mTOR pathway for axon regeneration after central nervous system injury ENSG00000179632 PMC5971270__F4 IPA identified “Tec kinase family signalling” as the canonical pathway in the cells with the highest predicted potential/significance of being affected by the treatment of caerin 1.9, based on iTRAQ data ENSG00000168040 ENSG00000136155 ENSG00000026103 PMC7279457__F2 Positioning Cx43 in the intercellular coupling by channels in the DC-T cell IS ENSG00000134982 ENSG00000110218 PMC6683209__F1 Cyclin D1-CDK4/6-RB pathway and crosstalk in breast cancer ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 ENSG00000146648 PMC10474074__F2 Kennedy pathway and Lands cycle in ferroptosis ENSG00000167468 ENSG00000111684 ENSG00000198670 PMC6429175__F8 Comprehensive pathway of Alzheimer’s disease derived from the Kyoto Encyclopedia of Genes and Genomes (KEGG) ENSG00000132906 ENSG00000291983 ENSG00000142192 ENSG00000002330 ENSG00000120868 ENSG00000168040 ENSG00000119912 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC9611857__F2 A Pathological Interaction between Beta-amyloid and Mitochondria in the Occurrence and Development of Alzheimer’s Disease ENSG00000116688 ENSG00000171109 ENSG00000214253 PMC9112566__F1 Endomembrane remodeling in SARS-CoV-2 infection ENSG00000130234 ENSG00000184012 PMC3372896__F3 Intersection of pathways controlling Wnt/Beta-catenin signaling and cadherin-mediated adhesion ENSG00000291971 ENSG00000138798 ENSG00000168036 ENSG00000077782 PMC3555267__F2 Typical MAPK signaling pathway ENSG00000162889 ENSG00000163914 PMC8147076__F1 Bioengineering of Genetically Encoded Gene Promoter Repressed by the Flavonoid Apigenin for Constructing Intracellular Sensor for Molecular Events ENSG00000110711 ENSG00000106546 PMC5187837__F1 The integrin outside-in signaling ENSG00000002330 ENSG00000198793 PMC2917906__F1 HIF-1A and HIF-2A have different functions in the cartilage ENSG00000154736 ENSG00000173039 ENSG00000163501 PMC11671575__F1 Signaling pathway of FOXF2 in tumor progression ENSG00000169554 ENSG00000137273 ENSG00000119669 ENSG00000109321 ENSG00000144560 ENSG00000168036 ENSG00000146648 PMC8268527__F1 Targeting NEDDylation as a Novel Approach to Improve the Treatment of Head and Neck Cancer ENSG00000144744 ENSG00000111530 ENSG00000285246 PMC8034822__F4 Divergent cytokine pathways drive fibrosis ENSG00000145777 ENSG00000166090 PMC8151747__F1 Pentose Phosphate Pathway in Yeasts–More Than a Poor Cousin of Glycolysis ENSG00000167900 PMC8151747__F2 Pentose Phosphate Pathway in Yeasts–More Than a Poor Cousin of Glycolysis ENSG00000167900 PMC5954996__F7 BACTEROIDES FRAGILIS TOXIN COORDINATES A PRO-CARCINOGENIC INFLAMMATORY CASCADE VIA TARGETING OF COLONIC EPITHELIAL CELLS ENSG00000134982 ENSG00000168036 ENSG00000168610 PMC7773148__F1 Fatty acid and endocannabinoid metabolism by cytochrome P450 classes ENSG00000186115 ENSG00000138115 ENSG00000186529 ENSG00000134716 ENSG00000186204 PMC5133730__F7 Wnt5a induces renal AQP2 expression by activating calcineurin signalling pathway ENSG00000167580 PMC11044490__F6 DEGs in plant hormone signal transduction pathway ENSG00000110934 ENSG00000221818 PMC7494970__F2 Involvement of Ang-II, ACE2, and Ang-1–7 in atherogenic pathways ENSG00000130234 ENSG00000086991 PMC4779544__F1 Proposed pathway connecting HMGB1, TLR4, TLR2, MyD88, and TRIF signaling to inflammation and regeneration following muscle ischemia ENSG00000189403 ENSG00000172936 ENSG00000136869 PMC4409274__F7 Cancer activates Stat3 in muscle to stimulate loss of muscle mass via two signaling pathways ENSG00000168610 PMC8957418__F3 Progress of Statin Therapy in the Treatment of Idiopathic Pulmonary Fibrosis ENSG00000163235 ENSG00000163914 PMC4646237__F9 Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway ENSG00000180210 ENSG00000169047 PMC10854933__F2 An illustration of the theoretical modes of action of the MRGPRX2 signaling pathway inhibitors ENSG00000183695 ENSG00000291971 ENSG00000293604 PMC3689254__F2 General scheme of EGFR activation ENSG00000198793 ENSG00000146648 PMC3689254__F3 EGFR activation of the Ras/Raf/MEK/MAPK pathway ENSG00000146648 PMC3689254__F6 Several flavonoid compounds also target the Fyn/Src signaling pathway ENSG00000115415 ENSG00000291971 ENSG00000010810 ENSG00000132646 PMC9526582__F10 Identification of Novel miRNAs, Targeting Genes, Signaling Pathway, and the Small Molecule for Overcoming Oxaliplatin Resistance of Metastatic Colorectal Cancer ENSG00000135218 ENSG00000288512 ENSG00000137507 ENSG00000138615 ENSG00000133961 ENSG00000112715 ENSG00000124253 PMC9348576__F2 Products of deregulated genes in Dp(16)1Yey/+ are enriched in proteins linked to glutamate receptor signaling pathway and in proteins involved in an ARC–PSD95 complex linked to ID and intelligence ENSG00000134909 ENSG00000292254 ENSG00000119125 PMC9526582__F13 Identification of Novel miRNAs, Targeting Genes, Signaling Pathway, and the Small Molecule for Overcoming Oxaliplatin Resistance of Metastatic Colorectal Cancer ENSG00000135218 ENSG00000124253 PMC7758035__F5 GA biosynthesis and inactivation, highlighting the GA signal transduction pathway that enables GA homeostasis ENSG00000105722 ENSG00000047410 PMC5036257__F7 A new SLIT/miR-218/(NFKB/POU2F2/ROBO1) signalling pathway promotes gastric cancer (GC) metastasis ENSG00000028277 ENSG00000145147 ENSG00000184347 PMC9512455__F7 Bile acid conjugation deficiency causes hypercholanemia, hyperphagia, islet dysfunction, and gut dysbiosis in mice ENSG00000276559 ENSG00000167910 PMC3317641__F7 Nuclear Factor Kappa B Activation Occurs in the Amnion Prior to Labour Onset and Modulates the Expression of Numerous Labour Associated Genes ENSG00000125398 ENSG00000011422 ENSG00000145623 ENSG00000175793 ENSG00000159461 ENSG00000232326 ENSG00000099860 ENSG00000070669 PMC6501790__F2 Epigenetic control and the circadian clock: linking metabolism to neuronal responses ENSG00000105835 ENSG00000177551 ENSG00000096717 ENSG00000168610 PMC8471000__F2 Metabolic Reprogramming and Host Tolerance: A Novel Concept to Understand Sepsis-Associated AKI ENSG00000077463 ENSG00000096717 PMC3317641__F6 Nuclear Factor Kappa B Activation Occurs in the Amnion Prior to Labour Onset and Modulates the Expression of Numerous Labour Associated Genes ENSG00000112972 ENSG00000148926 ENSG00000135069 ENSG00000135801 ENSG00000213853 ENSG00000136826 ENSG00000119681 ENSG00000137801 ENSG00000186081 ENSG00000157557 ENSG00000169469 ENSG00000186847 ENSG00000136997 PMC6743121__F8 Schematic depicting HSPA5 protects against DHA-induced ferroptosis in glioma cells ENSG00000128272 ENSG00000144895 ENSG00000167468 PMC6297832__F6 Proposed mechanisms of anthocyanin’s effect on NVU dysfunction after ischemic stroke ENSG00000162711 ENSG00000002330 PMC10531065__F8 Antitumor Effect of the DNA Polymerase Alpha Inhibitor ST1926 in Glioblastoma: A Proteomics Approach ENSG00000100714 ENSG00000092621 ENSG00000184110 ENSG00000119608 ENSG00000132383 ENSG00000169710 ENSG00000291387 ENSG00000122565 ENSG00000124795 PMC4539601__F4 Inferred network models capture oncogenic signaling pathways in melanoma ENSG00000175054 ENSG00000157764 ENSG00000291971 ENSG00000132646 ENSG00000168036 ENSG00000102104 PMC8292951__F1 RNA Methylation in Systemic Lupus Erythematosus ENSG00000145388 ENSG00000120833 ENSG00000114737 ENSG00000104432 ENSG00000165819 ENSG00000278693 PMC5554748__F8 Cofilin Mediates LPS-Induced Microglial Cell Activation and Associated Neurotoxicity Through Activation of NFKB and JAK-STAT Pathway ENSG00000115415 ENSG00000291971 ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC8975241__F1 Effect of PD-1 on T cell-mediated signaling pathways and metabolism ENSG00000291603 ENSG00000134982 ENSG00000010810 ENSG00000198793 ENSG00000131196 ENSG00000026103 PMC8975241__F2 Metabolic effects of PD-1 ablation or blockade in effector (Teff) and regulatory (Treg) T cells ENSG00000291971 ENSG00000198793 ENSG00000131196 PMC4539601__F2 Cluster-guided pathway analysis of the response map ENSG00000039537 ENSG00000002330 ENSG00000157764 ENSG00000291971 ENSG00000168036 ENSG00000171791 ENSG00000166278 ENSG00000149311 ENSG00000175054 ENSG00000132646 ENSG00000177606 ENSG00000102104 ENSG00000146648 PMC9601210__F7 Therapeutic Targeting of NFKB in Acute Lung Injury: A Double-Edged Sword ENSG00000173039 PMC7014257__F2 Strategies to overcome anti-angiogenic therapy resistance ENSG00000142627 ENSG00000275385 ENSG00000112715 PMC4906396__F5 Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes ENSG00000099985 PMC3474186__F3 Apoptotic signaling through tumor necrosis factor superfamily receptor 6 (Fas) and tumor necrosis factor receptor (TNFR) ENSG00000132906 ENSG00000102871 ENSG00000125538 ENSG00000120868 ENSG00000168040 ENSG00000127191 ENSG00000164305 ENSG00000026103 PMC3474186__F4 Signaling pathways mediated by rat sarcoma (Ras) and protein kinase B (Akt) ENSG00000132906 ENSG00000198793 ENSG00000164305 PMC8082996__F9 Serum-derived exosomes containing NEAT1 promote the occurrence of rheumatoid arthritis through regulation of miR-144-3p/ROCK2 axis ENSG00000168036 PMC7654839__F1 Optogenetic tools for remote activation of intracellular Ca2+ signaling ENSG00000167323 ENSG00000293604 ENSG00000104044 ENSG00000084774 PMC4021255__F3 Ingenuity Pathway Analysis of genes negatively regulated by unliganded GR ENSG00000110711 ENSG00000107562 ENSG00000113140 ENSG00000288335 ENSG00000115221 ENSG00000196562 ENSG00000169242 ENSG00000073849 ENSG00000115896 ENSG00000145861 ENSG00000135587 PMC4021255__F4 Ingenuity Pathway Analysis of genes positively regulated by unliganded GR ENSG00000213928 ENSG00000118971 ENSG00000184979 ENSG00000019582 ENSG00000067066 ENSG00000105612 ENSG00000138135 ENSG00000171631 ENSG00000173757 ENSG00000135114 ENSG00000158270 ENSG00000034510 ENSG00000291555 ENSG00000113494 PMC2938637__F2 Current model of early symbiotic signaling pathways ENSG00000125450 ENSG00000069248 PMC5302036__F3 Switching off malignant mesothelioma: exploiting the hypoxic microenvironment ENSG00000167601 ENSG00000163930 ENSG00000134057 ENSG00000198793 ENSG00000118971 ENSG00000095002 ENSG00000146648 ENSG00000159399 ENSG00000182179 PMC8534876__F8 Cofilin and Actin Dynamics: Multiple Modes of Regulation and Their Impacts in Neuronal Development and Degeneration ENSG00000164828 ENSG00000163914 ENSG00000182541 PMC8560683__F1 Klotho as Potential Autophagy Regulator and Therapeutic Target ENSG00000198793 ENSG00000171791 PMC8534876__F3 Cofilin and Actin Dynamics: Multiple Modes of Regulation and Their Impacts in Neuronal Development and Degeneration ENSG00000173599 ENSG00000164690 PMC8841529__F6 Immediate-Early, Early, and Late Responses to DNA Double Stranded Breaks ENSG00000163961 ENSG00000178971 ENSG00000257949 ENSG00000080345 ENSG00000253251 ENSG00000171984 ENSG00000107960 ENSG00000122376 PMC4870238__F1 Signal transduction pathways that mediate Treg resistance converge on the PI3K/Akt pathway ENSG00000174125 ENSG00000239732 ENSG00000082512 ENSG00000056558 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000168610 PMC2797270__F8 Summary of Trif-biased signaling and selective p38 activation by sMLA ENSG00000183735 ENSG00000170458 ENSG00000172005 ENSG00000172936 ENSG00000136869 PMC8648636__F2 Drug combination screening as a translational approach toward an improved drug therapy for chordoma ENSG00000019991 ENSG00000163235 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8841529__F1 Immediate-Early, Early, and Late Responses to DNA Double Stranded Breaks ENSG00000012061 ENSG00000080345 ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000310560 ENSG00000166508 ENSG00000112130 ENSG00000093009 ENSG00000149311 ENSG00000012048 ENSG00000105486 ENSG00000163961 ENSG00000132646 ENSG00000145321 ENSG00000197299 ENSG00000138385 PMC11594856__F1 Signaling pathway of CTLA-4 PMC8946661__F5 Systematic Review to Define the Multi-Faceted Role of Lysine Methyltransferase SETD7 in Cancer ENSG00000087245 ENSG00000101945 ENSG00000106571 ENSG00000078900 ENSG00000122691 ENSG00000164690 ENSG00000112715 ENSG00000145391 PMC9027775__F5 Human RelA Transgene on Murine Macrophage Inflammatory Responses ENSG00000124762 ENSG00000245848 ENSG00000156587 ENSG00000138755 ENSG00000104549 ENSG00000071051 ENSG00000155659 ENSG00000291918 ENSG00000171621 ENSG00000137267 ENSG00000115594 ENSG00000033867 ENSG00000163564 ENSG00000132109 ENSG00000284832 ENSG00000138449 ENSG00000204103 ENSG00000164109 ENSG00000162882 ENSG00000087074 ENSG00000185745 ENSG00000221869 ENSG00000007908 ENSG00000101811 ENSG00000125347 ENSG00000106100 ENSG00000143375 ENSG00000052802 ENSG00000132170 ENSG00000156675 ENSG00000154451 ENSG00000169245 ENSG00000135077 ENSG00000115884 ENSG00000117226 ENSG00000110395 ENSG00000065526 ENSG00000118503 ENSG00000165097 ENSG00000102970 ENSG00000175093 ENSG00000136160 ENSG00000135605 ENSG00000164949 ENSG00000291971 ENSG00000112715 ENSG00000106546 ENSG00000178573 ENSG00000115008 ENSG00000099985 ENSG00000073756 PMC7094200__F3 Other signaling mechanisms regulated by RSV in a DCM heart ENSG00000136869 ENSG00000175567 ENSG00000079999 PMC9640784__F2 Select mechanisms of HER2-targeted resistance ENSG00000135446 ENSG00000198793 ENSG00000026508 ENSG00000123374 ENSG00000105810 ENSG00000145113 PMC3242881__F6A Src REGULATES SPHINGOSINE-1-PHOSPHATE MEDIATED SMOOTH MUSCLE CELL MIGRATION ENSG00000291971 ENSG00000170989 ENSG00000213694 PMC8466012__F3 Oxygen as a Master Regulator of Human Pluripotent Stem Cell Function and Metabolism ENSG00000136997 ENSG00000124440 ENSG00000136826 ENSG00000159399 PMC8466012__F4 Oxygen as a Master Regulator of Human Pluripotent Stem Cell Function and Metabolism PMC5494602__F9 Model of TRAF3-dependent regulation of RIG-I signaling pathway by NS1/126-225 ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000121060 PMC8194041__F2 Stem cells in the treatment of renal fibrosis: a review of preclinical and clinical studies of renal fibrosis pathogenesis ENSG00000169554 PMC3876432__F3 IL-6-STAT3 signaling and premature senescence ENSG00000115008 ENSG00000109320 ENSG00000173039 ENSG00000169429 ENSG00000168610 ENSG00000115461 PMC2785637__F1 Schematic overview of hepatic lipid biosynthetic pathways ENSG00000042832 ENSG00000133027 PMC4065097__F1 Simulation of Swanson's Literature-Based Discovery: Anandamide Treatment Inhibits Growth of Gastric Cancer Cells In Vitro and In Silico ENSG00000110944 ENSG00000100591 ENSG00000152661 ENSG00000100490 ENSG00000172465 ENSG00000170458 ENSG00000131495 ENSG00000129355 ENSG00000073756 ENSG00000168610 PMC7445477__F7 Troxerutin on vascular inflammatory mediators and expression of microRNA-146a/NFKB signaling pathway in aorta of healthy and diabetic rats ENSG00000125538 ENSG00000175104 ENSG00000184216 PMC3594312__F5 Inactivation of DNA–Dependent Protein Kinase Promotes Heat–Induced Apoptosis Independently of Heat–Shock Protein Induction in Human Cancer Cell Lines ENSG00000023445 ENSG00000142192 ENSG00000130522 ENSG00000197429 ENSG00000056972 ENSG00000122877 ENSG00000120889 ENSG00000112715 ENSG00000127191 ENSG00000125347 ENSG00000136826 ENSG00000106546 ENSG00000128272 ENSG00000011422 ENSG00000175104 PMC3766771__F1 Transcriptional regulation of effector and memory CD8+ T cell fates ENSG00000138378 ENSG00000150907 ENSG00000198793 ENSG00000105656 ENSG00000127528 ENSG00000103522 ENSG00000168610 PMC6198389__F3 Possible therapeutic strategies for cancer stem cell elimination ENSG00000198793 ENSG00000026508 ENSG00000168036 ENSG00000118777 PMC3766771__F2 Transcriptional regulation of effector and memory CD8+ T cell fates PMC2287285__F7 Comparison models summarizing how eIF4E is not only downstream of the PI3K–AKT pathway (left) but can modulate this PI3K–Akt axis through NBS1 (right) ENSG00000134057 ENSG00000145386 ENSG00000140464 PMC12144634__F4 Cell cycle proteins: Linking the cell cycle to tumors ENSG00000149311 ENSG00000175054 ENSG00000123374 ENSG00000166851 PMC9603526__F2 Hydrogen Sulfide and Its Donors: Keys to Unlock the Chains of Nonalcoholic Fatty Liver Disease PMC4355290__F5 Changes in Protein Expression in Two Cholangiocarcinoma Cell Lines Undergoing Formation of Multicellular Tumor Spheroids In Vitro ENSG00000206075 ENSG00000186716 ENSG00000092820 ENSG00000171345 ENSG00000163631 PMC3478445__F12 Model of Stat3, Ascl1a, and Lin28a in inducing maximal Müller glial proliferation in the light-damaged zebrafish retina ENSG00000131914 ENSG00000113070 ENSG00000168610 PMC8473751__F6 Insight in the Recent Application of Polyphenols From Biomass ENSG00000087245 ENSG00000176692 ENSG00000081041 ENSG00000112242 ENSG00000163739 ENSG00000100985 ENSG00000096717 PMC8473751__F3 Insight in the Recent Application of Polyphenols From Biomass ENSG00000181019 ENSG00000023909 PMC7666735__F8 Mechanisms contributing to RES inhibiting the metastatic potential of cervical cancer cells ENSG00000149968 ENSG00000122691 ENSG00000170558 ENSG00000168610 PMC7072286__F6 Venn diagram illustrating differential molecular pathways in recGB vs ENSG00000012061 ENSG00000110721 ENSG00000163599 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000113318 ENSG00000132646 ENSG00000172086 ENSG00000170430 ENSG00000129071 ENSG00000051180 ENSG00000113263 ENSG00000177084 ENSG00000095002 ENSG00000183479 ENSG00000136936 PMC11897911__F6 PGAM5 activating NFKB signaling pathway to promote polarization of M1 macrophages ENSG00000198793 ENSG00000247077 PMC7547764__F1 c-MET/HGF pathway in gastric cancer pathogenesis ENSG00000019991 ENSG00000291971 ENSG00000198793 ENSG00000146648 PMC7897492__F6 Working Model ENSG00000188486 ENSG00000166439 ENSG00000101751 ENSG00000105204 PMC9250438__F6 Association of PTPRT Mutations with Cancer Metastasis in Multiple Cancer Types ENSG00000019991 ENSG00000087245 ENSG00000196090 ENSG00000168610 PMC9437119__F8 Mid51/Fis1 mitochondrial oligomerization complex drives lysosomal untethering and network dynamics ENSG00000168958 ENSG00000214253 PMC5605936__F1 Antiviral apoptotic pathways ENSG00000183735 ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000164342 PMC4611218__F3 Effect of oral foreign plasmid pcDNA3 on complement activation classical pathway ENSG00000039537 ENSG00000113600 ENSG00000291559 ENSG00000132341 PMC155392__F3 Predicted pathways for degradation, transport, and metabolism of chitin by M ENSG00000198951 PMC4611218__F2 Effect of orally administered foreign plasmid pDNA3 on proteasome degradation pathway ENSG00000111537 ENSG00000163902 ENSG00000077721 ENSG00000131508 ENSG00000170142 ENSG00000107341 ENSG00000170035 ENSG00000291973 ENSG00000119048 PMC8124914__F2 Nitric Oxide as a Target for Phytochemicals in Anti-Neuroinflammatory Prevention Therapy ENSG00000163914 PMC4581061__F3 Induction of the extrinsic pathway of apoptosis by phthalates ENSG00000185591 ENSG00000026103 PMC8902906__F3 Biological and multifunctional roles of IL-38 in different infectious diseases and COVID-19 ENSG00000111537 ENSG00000163739 ENSG00000115009 PMC3514880__F3 Genome sequences of wild and domestic bactrian camels ENSG00000171105 ENSG00000110395 ENSG00000005882 ENSG00000150907 ENSG00000198793 PMC9156568__F15 Characterizing the Propagation Pathway of Neuropathological Events of Alzheimer’s Disease Using Harmonic Wavelet Analysis ENSG00000213658 ENSG00000177084 PMC5571732__F1 Methionine metabolic pathway ENSG00000151224 ENSG00000116984 PMC3924811__F2 Mechanosignaling in Bone Health, Trauma and Inflammation ENSG00000291971 ENSG00000177606 PMC4526774__F2 Pim signaling in MM ENSG00000163435 ENSG00000002330 ENSG00000136997 PMC8046019__F1 Ghrelin-induced effector pathways and unavowed signaling hotspots ENSG00000177169 ENSG00000164406 ENSG00000112964 ENSG00000291971 ENSG00000198793 ENSG00000096717 PMC3512188__F3 Roles of miRNAs in DNA damage response ENSG00000188486 ENSG00000149311 ENSG00000070831 ENSG00000096717 PMC8199999__F1 Minor Intron Splicing from Basic Science to Disease ENSG00000169249 ENSG00000185946 PMC8199999__F6 Minor Intron Splicing from Basic Science to Disease ENSG00000273772 ENSG00000164902 ENSG00000092208 PMC8718186__F1 cGAS‒STING signaling and function in metabolism and kidney diseases ENSG00000183735 ENSG00000164430 PMC8161298__F1 TP53 Pathway Inactivation in Embryonic and Somatic Cells—Relevance for Understanding (Germ Cell) Tumorigenesis ENSG00000164362 PMC3857355__F8 Therapeutic strategies that have been used to target the TGFB signaling pathway to reduce scarring PMC3163574__F2 Identification and Visualization of CD8+ T Cell Mediated IFNG Signaling in Target Cells during an Antiviral Immune Response in the Brain ENSG00000159128 ENSG00000111537 ENSG00000115415 ENSG00000027697 PMC3430731__F1 Signaling pathways regulating lipogenesis in cancer cells ENSG00000198793 ENSG00000136997 ENSG00000172005 ENSG00000198074 ENSG00000169710 ENSG00000017483 ENSG00000078237 PMC4359552__F1 Conceptual model of general lifestyle effects, salient CHD pathogenetic pathways and CHD hallmarks ENSG00000162711 ENSG00000162692 ENSG00000005381 PMC11570929__F4 mTOR signaling pathway and cellular senescence ENSG00000135446 ENSG00000155792 ENSG00000186654 PMC11570929__F5 Insulin-like signaling pathway and cellular senescence ENSG00000169047 ENSG00000198793 ENSG00000168610 PMC8161298__F7 TP53 Pathway Inactivation in Embryonic and Somatic Cells—Relevance for Understanding (Germ Cell) Tumorigenesis ENSG00000150457 ENSG00000159335 ENSG00000102974 ENSG00000198625 PMC3857355__F3 TGFB/Smad signal transduction pathway PMC8738154__F5 Molecular characteristics and clinical outcomes of patients with Neurofibromin 1-altered metastatic colorectal cancer ENSG00000138798 ENSG00000198793 ENSG00000146648 ENSG00000196712 PMC3757373__F1 Methionine metabolism in liver PMC5865700__F1 Shh signaling pathway ENSG00000164690 ENSG00000128602 PMC9218565__F1 Nicotinamide N-Methyltransferase: A Promising Biomarker and Target for Human Cancer Therapy ENSG00000167258 ENSG00000012048 ENSG00000087245 ENSG00000105835 ENSG00000198793 ENSG00000026508 ENSG00000185591 ENSG00000168610 PMC4273979__F1 Pikromycin and methymycin biosynthetic pathway in Streptomyces venezuelae ATCC 15439 PMC3315683__F1 Phosphatidylinositol 3-kinase signaling pathway ENSG00000109452 PMC3682211__F7 Aspirin targets multiple components of the AMPK/mTOR signaling pathway in colorectal cancer ENSG00000198793 PMC9484965__F9 Quantitative Expression of SFN, lncRNA CCDC18-AS1, and lncRNA LINC01343 in Human Breast Cancer as the Regulator Biomarkers in a Novel ceRNA Network: Based on Bioinformatics and Experimental Analyses ENSG00000002330 PMC3828604__F1 Interactions of stress proteins and cell surface TLR signaling pathways ENSG00000149311 ENSG00000183735 ENSG00000284774 ENSG00000128272 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000100219 ENSG00000175104 ENSG00000184216 PMC6767494__F1 Management of cancer by fecal microbiota transplant ENSG00000168036 ENSG00000168610 PMC3828604__F3 Stress proteins in crosstalk with cytoplasmic PRR signaling ENSG00000183735 ENSG00000128272 ENSG00000167207 ENSG00000131323 ENSG00000106100 ENSG00000276561 PMC6480560__F1 Transcriptional changes of type I interferon (IFN-I) signaling pathway members in the cerebellum of canine distemper virus (CDV)-infected compared to control dogs ENSG00000213928 ENSG00000187608 ENSG00000105397 ENSG00000089127 ENSG00000115415 ENSG00000183486 ENSG00000157601 ENSG00000135114 ENSG00000172936 ENSG00000125347 ENSG00000276561 ENSG00000164342 PMC11855671__F6 Biosynthetic and signal transduction pathways of SA ENSG00000158104 PMC6498735__F1 Regulatory pathways leading to stem-like cells underlie prostate cancer progression ENSG00000136997 ENSG00000026508 ENSG00000129514 PMC3621568__F1 TGFB transduces signaling through Smad and non-Smad signaling pathways ENSG00000198742 ENSG00000177606 PMC1998884__F1 Pathways involved in GSIS ENSG00000173599 ENSG00000172005 ENSG00000079432 ENSG00000184207 ENSG00000062485 PMC8085809__F2 Microbiota signalling to the host circadian and metabolic systems occurs via both contact-dependent mechanisms and contact-independent mechanisms ENSG00000186575 ENSG00000131096 ENSG00000026103 PMC3209802__F1 Assembly of checkpoint and repair machineries at DNA damage sites ENSG00000188486 ENSG00000149311 ENSG00000112130 PMC10909944__F9 Mechanistic schematic model of action of circRNA_SLC8A1 in macrophages against Mtb infection ENSG00000284099 PMC6736526__F3 Non-nociceptive roles of opioids in the CNS: opioids’ effects on neurogenesis, learning, memory and affect ENSG00000164879 ENSG00000148400 ENSG00000117707 PMC11036733__F6 Dengue virus pathogenesis and host molecular machineries ENSG00000164430 ENSG00000278211 ENSG00000182326 PMC4547409__F9 Model illustrating the mechanism underlying inhibition of TGFB1–induced EMT and cell migration by KF PMC8910364__F9 Diesel Particulate Extract Accelerates Premature Skin Aging in Human Fibroblasts via Ceramide-1-Phosphate-Mediated Signaling Pathway ENSG00000149968 PMC12121910__F4 Integrative analysis of metabolomics and transcriptomics revealing activation of lignin biosynthesis pathway in rice infected by Pst ENSG00000105227 ENSG00000084774 PMC6844540__F12 PI3K-AKT signaling pathway adapted from KEGG (ID: hsa04151) (A) the predicted targets and genes were signed in red; (B) the known targets and genes were signed in red ENSG00000177455 ENSG00000124102 ENSG00000103479 ENSG00000065833 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000120885 PMC6746687__F3 Schematic diagram of EB virus involved in the G1/S transition ENSG00000149311 ENSG00000116017 ENSG00000135446 ENSG00000132646 ENSG00000105810 PMC9449326__F2 Network pharmacology and experimental analysis to reveal the mechanism of Dan-Shen-Yin against endothelial to mesenchymal transition in atherosclerosis ENSG00000019991 ENSG00000002330 ENSG00000109320 ENSG00000138798 ENSG00000198793 ENSG00000173039 ENSG00000150093 ENSG00000112715 ENSG00000177455 ENSG00000012048 ENSG00000066468 ENSG00000103479 ENSG00000128272 ENSG00000186716 ENSG00000136997 ENSG00000123374 ENSG00000146648 PMC8085147__F2 CGAS–STING signaling pathway senses cytosolic DNA derived from either viral/bacterial infection or self-DNA ENSG00000164430 PMC6412864__F3 Apoptotic signaling during ER stress ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC6895604__F2 Targeting senescent cells in translational medicine ENSG00000149311 ENSG00000175054 ENSG00000002330 ENSG00000168214 ENSG00000143815 ENSG00000198793 PMC6412864__F2 Crosstalk between UPR and autophagy ENSG00000128272 ENSG00000144895 ENSG00000078081 ENSG00000005893 ENSG00000100219 PMC3001129__F2 NOD-like receptor signaling beyond the inflammasome ENSG00000111537 ENSG00000167207 ENSG00000160703 ENSG00000142405 ENSG00000172936 ENSG00000107201 ENSG00000106100 ENSG00000184216 PMC3539662__F1 Kaposi sarcoma-associated herpesvirus K1 activates PI3K/AKT/mTOR signaling thereby activating protein synthesis and survival pathways, while inhibiting apoptotic pathways ENSG00000198793 PMC3565070__F3 Pyocyanin effects on respiratory epithelium: relevance in Pseudomonas aeruginosa airway infections ENSG00000081041 ENSG00000163739 ENSG00000115590 ENSG00000113070 ENSG00000121966 ENSG00000163734 ENSG00000001626 ENSG00000117983 ENSG00000005381 ENSG00000162892 ENSG00000146648 ENSG00000293532 ENSG00000167419 PMC6859544__F1 Redox Regulation in Glucose Metabolism ENSG00000026103 PMC5393166__F1 Schematic overview of the Nrf2 pathway ENSG00000178573 ENSG00000100387 ENSG00000079999 PMC5853106__F2 Non-Canonical Wnt-signaling: Non-canonical Wnt/PCP (planar cell polarity) pathway ENSG00000087095 ENSG00000070831 PMC8655231__F2 Functional Role of Lactoferrin in Intestine Mucosal Immune System and Inflammatory Bowel Disease ENSG00000119688 ENSG00000168036 ENSG00000172936 ENSG00000157625 ENSG00000083799 ENSG00000184216 PMC5853106__F3 Wnt Signaling Pathway in Cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9402571__F6 Models for the negative regulation of NFKB signaling pathways by caspase-3-mediated cleavage of NFKBs ENSG00000132906 ENSG00000168040 ENSG00000164305 PMC5853106__F1 The Wnt Signaling Pathway in Cancer ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9243210__F2 Metabolic reprogramming and epigenetic modifications on the path to cancer ENSG00000147162 ENSG00000198408 ENSG00000108773 PMC5805151__F1 Interaction between stress responses and circadian metabolism in metabolic disease ENSG00000105516 ENSG00000100219 PMC7984428__F2 Simplified canonical model of NMD pathway activation (A) in human cells which is controlled by three different ways so far and yet to be identified (B) ENSG00000151461 ENSG00000070366 ENSG00000125351 ENSG00000114127 ENSG00000157106 PMC8273387__F4 Cullin Deneddylation Suppresses the Necroptotic Pathway in Cardiomyocytes ENSG00000137275 ENSG00000171791 ENSG00000168404 ENSG00000064012 ENSG00000285379 PMC3502514__F1 Activation of stress signalling pathways in the liver of sows during lactation ENSG00000132693 PMC8273387__F2 Cullin Deneddylation Suppresses the Necroptotic Pathway in Cardiomyocytes ENSG00000137275 ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000154124 ENSG00000127191 ENSG00000285379 PMC8374049__F2 Inflammasome Signaling: A Novel Paradigm of Hub Platform in Innate Immunity for Cancer Immunology and Immunotherapy ENSG00000278718 ENSG00000147697 ENSG00000073605 PMC11673533__F1 Artificial sweeteners affect hormonal pathways in breast cancer PMC3203793__F1 Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling ENSG00000134982 ENSG00000283100 PMC4679438__F3 mTOR and its tight regulation for iNKT cell development and effector function ENSG00000084774 PMC9102229__F7 Multiomic Profiling Identified EGF Receptor Signaling as a Potential Inhibitor of Type I Interferon Response in Models of Oncolytic Therapy by Vesicular Stomatitis Virus ENSG00000115415 ENSG00000168610 ENSG00000146648 PMC5492169__F9 Schematic model describing the CD99 peptide-induced signal transduction pathway ENSG00000292348 ENSG00000127445 PMC4679438__F2 mTOR and its tight regulation for iNKT cell development and effector function ENSG00000158473 ENSG00000010810 PMC6722098__F1 DEGs’ products protein-protein interaction network for each mineral ENSG00000105664 ENSG00000011007 ENSG00000133110 ENSG00000038427 ENSG00000276286 ENSG00000184831 PMC6155514__F5 Real-time carbon allocation into biogenic volatile organic compounds (BVOCs) and respiratory carbon dioxide (CO2) traced by PTR-TOF-MS, 13CO2 laser spectroscopy and 13C-pyruvate labelling ENSG00000197429 PMC4632296__F8 A working model depicting that RILP interacts with RalGDS to inhibit Ral pathway ENSG00000006451 ENSG00000274145 PMC6628296__F1 Canonical Wnt signaling pathway illustrating therapeutic intervention points targeted by Wnt modulators ENSG00000281324 ENSG00000162337 ENSG00000102312 ENSG00000168036 PMC3203793__F6 Molecular modulation of peripheral myelination by the Sirt2/Par-3/aPKC pathway ENSG00000134982 ENSG00000283100 PMC6231577__F1 Effect of radiotherapy on DNA repair, mitochondrial function, cellular ROS, and EMT ENSG00000143799 ENSG00000188486 ENSG00000149311 ENSG00000134057 ENSG00000198793 ENSG00000138385 ENSG00000105227 PMC5543744__F6 Proposed mechanism of hypoxic-conditioned secretome effects on liver regeneration ENSG00000096717 ENSG00000168610 PMC3464683__F3 Schematic representation of a plant cell with the major components involved in symbiotic signaling and defense signaling ENSG00000088320 ENSG00000125450 ENSG00000069248 PMC6865084__F3 Core genes involved in the promotion of depression in patients with ovarian cancer ENSG00000100234 ENSG00000125740 ENSG00000107562 ENSG00000128016 ENSG00000130522 ENSG00000113140 ENSG00000162772 ENSG00000104368 ENSG00000108691 ENSG00000291748 ENSG00000146070 ENSG00000111666 ENSG00000152952 ENSG00000168081 ENSG00000127616 ENSG00000188783 PMC6215314__F6 Illustration of heterogeneous cancer death induced by dihydroartemisinin plus epirubicin liposomes through autophagy, apoptosis and necrosis ENSG00000198382 ENSG00000126775 PMC7902034__F3 Activation of the cyclic GMP-AMP (cGAMP) synthase (cGAS)-stimulator of IFN genes (STING) signaling pathway and AIM2/IFI16 inflammasome ENSG00000278718 ENSG00000164430 ENSG00000167323 ENSG00000173638 ENSG00000163568 ENSG00000125538 ENSG00000163565 PMC8164981__F1 Bhlhe40 as a TRM metabolic regulator ENSG00000148400 ENSG00000020633 ENSG00000283060 PMC4260746__F4 Caspase-1 activation by inflammasomes leads to pro-inflammatory cytokine production: Inflammasomes can be triggered by various stimuli ENSG00000162711 ENSG00000125538 ENSG00000091592 ENSG00000189403 ENSG00000172936 ENSG00000091106 ENSG00000150455 PMC5894239__F5 Functional network overrepresented in the list of differentially expressed miRNAs in response to infection of bovine macrophages with Streptococcus agalactiae strain (a) ST103 and (b) ST12 ENSG00000170262 PMC7294136__F1 Functions of extracellular S100A4 protein ENSG00000196154 ENSG00000168036 ENSG00000136869 PMC7902034__F1 Localization, intracellular trafficking, and signaling pathways of nucleic acid-sensing Toll-like receptors (TLRs) ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000131323 ENSG00000110057 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC3747383__F1 PPARG transduction pathway PMC4671727__F1 Complement Effectors of Inflammation in Cystic Fibrosis Lung Fluid Correlate with Clinical Measures of Disease ENSG00000039537 ENSG00000166278 PMC96649__F4 Stimulation of iNOS production by Pln is dependent on the IFNG signaling pathway ENSG00000115415 ENSG00000125347 ENSG00000007171 PMC2858523__F1 Schematic diagram showing the RAS-MAPK signal transduction pathway and affected disease genes in disorders of the neurocardiofacialcutaneous syndrome family ENSG00000157764 ENSG00000115904 ENSG00000166068 ENSG00000108061 ENSG00000062485 PMC7857397__GA Neutralizing auto-Abs to type I IFNs underlie life-threatening COVID-19 pneumonia ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC3010252__F1 Disorders of dysregulated signal traffic through the RAS-MAPK pathway: phenotypic spectrum and molecular mechanisms ENSG00000157764 ENSG00000115904 ENSG00000166068 ENSG00000108061 ENSG00000196712 ENSG00000062485 PMC9470853__F7 Fatty acid export (FAX) proteins contribute to oil production in the green microalga Chlamydomonas reinhardtii ENSG00000083857 ENSG00000107331 ENSG00000026103 PMC11602941__F2 TGFB family signaling pathway ENSG00000170365 ENSG00000137834 ENSG00000156574 PMC11602941__F3 TGFB family signaling in human pluripotent stem cells ENSG00000170365 ENSG00000156574 PMC7882887__F4 Emerging role of estrogen related receptorA in complications of non-small cell lung cancers ENSG00000198793 PMC5003543__F4 Working model of consequences of PREX2 truncating mutations ENSG00000129757 ENSG00000046889 PMC7196371__F9 Functions of HT in AD ENSG00000168610 ENSG00000079999 PMC7324377__F1 Biological pathways associated with the response to Ni(S-tcitr)2 in yeast PMC4654310__F6 Schematic model of SOCS-1 induction in a TLR4/MyD88-dependent and IFN-Beta-dependent signaling pathway ENSG00000115415 ENSG00000172936 ENSG00000136869 PMC7809757__F1 EDA signaling pathway ENSG00000186197 ENSG00000135960 ENSG00000175104 PMC9453694__F1 Neuropilin-2b facilitates resistance to tyrosine kinase inhibitors in non–small cell lung cancer ENSG00000146648 PMC7902134__F3 Yixin-Shu Capsules Ameliorated Ischemia-Induced Heart Failure by Restoring Trx2 and Inhibiting JNK/p38 Activation ENSG00000088256 ENSG00000177455 ENSG00000092054 ENSG00000148798 ENSG00000197594 ENSG00000291837 ENSG00000170893 ENSG00000160808 ENSG00000119782 ENSG00000108821 ENSG00000177666 ENSG00000177600 ENSG00000155657 ENSG00000198947 ENSG00000118972 ENSG00000168530 ENSG00000112280 ENSG00000163126 ENSG00000149380 ENSG00000138029 ENSG00000081248 ENSG00000269335 ENSG00000115267 ENSG00000198929 ENSG00000101306 ENSG00000036828 ENSG00000102854 ENSG00000125995 ENSG00000163217 ENSG00000132170 ENSG00000140416 ENSG00000122367 ENSG00000182533 ENSG00000277586 ENSG00000129038 ENSG00000172936 PMC8480058__F2 Macrophages and cancer stem cells: a malevolent alliance ENSG00000111801 ENSG00000116106 ENSG00000291971 ENSG00000026508 PMC8041205__F8 TcpC inhibits toll-like receptor signaling pathway by serving as an E3 ubiquitin ligase that promotes degradation of myeloid differentiation factor 88 ENSG00000072401 ENSG00000172936 ENSG00000175104 PMC10474437__F2 Differentially expressed non-coding RNAs and their regulatory networks in liver cancer ENSG00000019991 ENSG00000170365 ENSG00000163235 ENSG00000291971 ENSG00000134982 ENSG00000135446 ENSG00000138798 ENSG00000050165 ENSG00000168036 ENSG00000129514 ENSG00000105810 ENSG00000168610 PMC7530268__F1 Ferroptotic cascade ENSG00000151012 ENSG00000167468 ENSG00000167996 ENSG00000122873 ENSG00000079999 PMC7689683__F1 Signaling pathways of three estrogen receptors ENSG00000291971 ENSG00000113070 ENSG00000146648 PMC6280671__F4 Integrated Analysis Reveals Genomic and Expression Alterations in Signaling Pathways in HNSCC Differing in HPV Status ENSG00000104812 ENSG00000137713 ENSG00000110330 ENSG00000282905 ENSG00000198793 ENSG00000120889 ENSG00000168036 ENSG00000105647 ENSG00000166851 ENSG00000121879 ENSG00000164305 ENSG00000124762 ENSG00000175054 ENSG00000150907 ENSG00000077782 ENSG00000139687 ENSG00000064012 ENSG00000023445 ENSG00000175793 ENSG00000168040 ENSG00000149311 ENSG00000117020 ENSG00000041880 ENSG00000161202 ENSG00000149554 ENSG00000146648 ENSG00000133119 ENSG00000105723 ENSG00000173273 PMC11058355__F2 Functions of Mincle ENSG00000187796 PMC9601310__F7 Sorting nexin 17 increases low-density lipoprotein receptor-related protein 4 membrane expression: A novel mechanism of acetylcholine receptor aggregation in myasthenia gravis ENSG00000134569 ENSG00000030304 PMC2686112__F1 VHL gene complex targets hypoxia-inducible factors (HIF) for ubiquitin-mediated degradation ENSG00000180210 ENSG00000134086 ENSG00000163235 ENSG00000146648 PMC5953846__F8 Reversal of drug resistance by planetary ball milled (PBM) nanoparticle loaded with resveratrol and docetaxel in prostate cancer ENSG00000103222 ENSG00000214285 ENSG00000168040 ENSG00000118777 PMC3336107__F1 The Unfolded Protein Response in the ER ENSG00000128272 ENSG00000100219 PMC3154715__F3 Working model of relaxin sustained-vasodilatory response PMC8268128__F2 Adipose Tissue-Derived Extracellular Vesicles and the Tumor Microenvironment: Revisiting the Hallmarks of Cancer ENSG00000149311 ENSG00000134086 ENSG00000108691 ENSG00000125398 ENSG00000149968 ENSG00000164362 ENSG00000168036 ENSG00000168610 PMC5097071__F6 Redox homeostasis and metabolic changes during the adaptation to proteasome inhibitors ENSG00000131473 ENSG00000167107 ENSG00000176715 PMC4664160__F4 Druggable Sensors of the Unfolded Protein Response ENSG00000162711 ENSG00000128272 ENSG00000144895 ENSG00000265972 ENSG00000171791 PMC2696125__F2 Docosanoids are multifunctional regulators of neural cell integrity and fate: significance in aging and disease ENSG00000100290 ENSG00000002330 PMC7058937__F2 Cell junction formation and maturation under RhoGTPase control in epithelial cells ENSG00000070831 ENSG00000163914 ENSG00000165527 ENSG00000133961 PMC11959089__F1 Overview Diagram of Ferroptosis Mechanism in Mycobacterium tuberculosis, EB Virus, and SARS-CoV-2 Infections ENSG00000151012 ENSG00000167468 ENSG00000119383 ENSG00000073756 PMC6482429__F1 Molecular pathways targeted by the TCMs covered in this review are summarized ENSG00000137275 ENSG00000198793 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000168404 ENSG00000096717 ENSG00000142082 ENSG00000127191 ENSG00000285379 ENSG00000026103 PMC7404778__F2 Graphical representation of the mechanism of action of bioactive compounds on the antioxidant and immune response ENSG00000178573 ENSG00000005381 ENSG00000079999 PMC9319825__F1 Emerging Biomarker-Guided Therapies in Prostate Cancer ENSG00000198793 PMC3051174__F3 TLR4 signaling – a converged immune response pathway for hemorrhagic shock and septic shock ENSG00000172936 ENSG00000136869 PMC10975235__F2 Type I IFN signaling ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000198793 ENSG00000168610 ENSG00000276561 ENSG00000142166 PMC5572260__F4 Signaling in human glioblastoma cell lines after treatment with vascular endothelial growth factor (VEGF), irradiation and axitinib ENSG00000162889 ENSG00000070831 ENSG00000198300 PMC5569752__F1 ER stress-mediated apoptosis and inflammation in cardiovascular disease ENSG00000162711 ENSG00000128272 ENSG00000144895 ENSG00000265972 PMC5569752__F2 Chronic effect of exercise on the ER stress-associated apoptosis and inflammation ENSG00000162711 ENSG00000125538 ENSG00000265972 PMC5059456__F9 Regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways ENSG00000134982 ENSG00000168036 ENSG00000168610 ENSG00000196628 PMC8999618__F2 Sequence Requirements for miR-424-5p Regulating and Function in Cancers ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000126775 ENSG00000135446 ENSG00000136997 ENSG00000123374 ENSG00000112715 ENSG00000276876 PMC8999618__F3 Sequence Requirements for miR-424-5p Regulating and Function in Cancers ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000171791 ENSG00000175567 ENSG00000142082 ENSG00000168610 ENSG00000164305 ENSG00000284495 ENSG00000137807 ENSG00000198901 ENSG00000184675 ENSG00000172005 ENSG00000120868 PMC7535921__F8 Acetylation modulates the Fanconi anemia pathway by protecting FAAP20 from ubiquitin-mediated proteasomal degradation ENSG00000171720 ENSG00000144554 PMC2984500__F2 Selection of miRNA implicated in the TLR4 signalling pathway ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC9700348__F1 Laminin-511 Activates the Human Induced Pluripotent Stem Cell Survival via A6B1 Integrin-Fyn-RhoA-ROCK Signaling ENSG00000010810 ENSG00000163914 PMC6274979__F1 The activation of Yes-associated protein (YAP) and the transcriptional coactivator with PDZ-binding motif (TAZ) in epithelial cells and fibroblasts ENSG00000167601 ENSG00000109321 ENSG00000089685 PMC2694443__F8 BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway ENSG00000281324 ENSG00000162337 ENSG00000167941 PMC8034969__F8 JAK-STAT signaling pathway and other related signaling pathway as well as the mechanism of the function of inhibitors identified in this study ENSG00000138798 ENSG00000198793 PMC8007386__F6 Model depicting the role for microvillous cells involvement in the olfactory epithelium innate immune response to viral infection ENSG00000214415 ENSG00000095303 ENSG00000197943 ENSG00000070985 ENSG00000166090 ENSG00000056736 ENSG00000275565 ENSG00000121060 PMC5837624__F1 Proposed mechanisms of cell injury induced by APOL1 variants ENSG00000162711 ENSG00000125538 ENSG00000142405 ENSG00000136869 PMC6862063__F12 Schematic summary of IL-6 induced effects on the JAK-STAT pathway and its main regulator, SOCS ENSG00000168610 PMC3179880__F2 Functional role of skeletal muscle-derived neurotrophic factors after exercise ENSG00000198793 PMC9382818__F1 Improved energy efficiency in microbial fuel cells by bioethanol and electricity co-generation ENSG00000198125 ENSG00000146701 PMC8532137__F1 Nuclear receptors of NR1 and NR4 subfamilies in the regulation of microglial functions and pathology ENSG00000182578 ENSG00000125538 ENSG00000186104 ENSG00000135929 PMC3931066__F7 Activation of the ATR-signaling pathway during G1/G0 or G2-M phases of the cell cycle ENSG00000175054 ENSG00000164053 ENSG00000132646 ENSG00000136936 PMC8579187__F4 Interactions between the renin–angiotensin, complement and kallikrein–kinin systems on the vascular wall ENSG00000039537 ENSG00000009724 ENSG00000113600 ENSG00000291559 ENSG00000130234 ENSG00000182326 PMC9221635__F2 Telomere Maintenance and the cGAS-STING Pathway in Cancer ENSG00000149311 ENSG00000145912 ENSG00000130826 ENSG00000109534 ENSG00000291996 ENSG00000164362 ENSG00000051180 ENSG00000096717 PMC9221635__F3 Telomere Maintenance and the cGAS-STING Pathway in Cancer ENSG00000183735 ENSG00000164430 PMC11761133__F5 Functional model of resilience ENSG00000189056 ENSG00000169783 ENSG00000162849 ENSG00000131095 ENSG00000091879 ENSG00000157005 ENSG00000274665 ENSG00000136826 ENSG00000081923 PMC7403229__F7 Mechanisms by which melatonin ameliorates oxidative stress via modulation of the Nrf2 pathway in cryopreserved OTs PMC8579187__F1 Renin–angiotensin system ENSG00000130234 ENSG00000137509 PMC11276752__F1 Deciphering Drug Resistance: Investigating the Emerging Role of Hyaluronan Metabolism and Signaling and Tumor Extracellular Matrix in Cancer Chemotherapy ENSG00000109814 ENSG00000170961 ENSG00000163914 ENSG00000026508 PMC6585057__F7 Summary and schematic diagram of this study ENSG00000169245 ENSG00000275214 ENSG00000224320 ENSG00000115415 ENSG00000157601 ENSG00000135114 ENSG00000276561 PMC11677181__F1 Wnt signaling pathways and the targets of their inhibitors ENSG00000100592 ENSG00000134982 ENSG00000177606 ENSG00000102312 ENSG00000168036 ENSG00000173273 PMC2662567__F2 Genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders ENSG00000019991 ENSG00000011422 ENSG00000198793 ENSG00000026508 ENSG00000122194 ENSG00000196712 PMC6162743__F7 Prx II regulates CSC properties of colorectal cancers via PI3K/AKT, Hedgehog and Wnt/Beta-Catenin signaling ENSG00000134982 ENSG00000168036 ENSG00000128602 ENSG00000105227 PMC2662567__F3 Genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders ENSG00000011422 ENSG00000198793 ENSG00000196712 PMC11864756__SF1_3. Analyses of differentially expressed genes that were enriched at different timepoints ENSG00000142192 ENSG00000138166 ENSG00000143507 ENSG00000198517 PMC7497778__F2 Functions of HSCARG in the cytoplasm ENSG00000102871 ENSG00000131323 ENSG00000127191 PMC3339861__F3 EGF decreases sphingolipid biosynthesis transcripts ENSG00000167769 ENSG00000103089 ENSG00000138798 ENSG00000143753 ENSG00000164023 ENSG00000166224 ENSG00000119537 ENSG00000148154 ENSG00000172296 ENSG00000168350 ENSG00000163082 PMC3339861__F4 EGF decreases free fatty acid (FFA) biosynthesis transcripts ENSG00000152463 ENSG00000149084 ENSG00000138798 ENSG00000169710 PMC4559887__F1 Homocysteine metabolism and major factors associated with hyperhomocysteinemia in rheumatoid arthritis patients ENSG00000205221 PMC6162743__F2 Overexpressed Prx II regulates stemness-associated properties of HCC cells ENSG00000119888 ENSG00000105227 PMC9313346__F2 P2 Receptors: Novel Disease Markers and Metabolic Checkpoints in Immune Cells ENSG00000134982 ENSG00000198793 ENSG00000110218 PMC5546018__F1 NDRG1 inhibits oncogenic signaling pathways by down-regulating the ErbB family of receptors ENSG00000163235 ENSG00000149269 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC5512074__F6 Schematic overview of p90RSK-mediated regulation of UBR5-containing miRISC ENSG00000183735 ENSG00000104517 ENSG00000131323 PMC9125963__F2 Mechanisms involved in controlling RNA virus-induced intestinal inflammation ENSG00000183735 ENSG00000117020 ENSG00000088888 ENSG00000109606 ENSG00000174885 ENSG00000174953 ENSG00000172936 ENSG00000131323 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC9125963__F3 Mechanisms involved in controlling RNA virus-induced intestinal inflammation ENSG00000183735 ENSG00000088888 ENSG00000109606 ENSG00000174885 ENSG00000276561 PMC12143691__F1 Gut microbiota interacts with the mammalian epigenome by generating epigenetic substrates or acting as regulators for chromatin-modifying enzymes ENSG00000145388 ENSG00000108773 ENSG00000091542 ENSG00000146457 ENSG00000165819 PMC9125963__F4 Mechanisms involved in controlling RNA virus-induced intestinal inflammation ENSG00000278718 ENSG00000162711 ENSG00000109606 ENSG00000174885 PMC12143691__F2 Epigenetic modifications induced by gut microbiota promote inflammatory bowel disease (IBD) ENSG00000145388 ENSG00000162711 ENSG00000171720 ENSG00000049768 ENSG00000086548 ENSG00000057663 ENSG00000106546 ENSG00000108840 PMC6002427__F3 Signaling pathways in mast cell biology ENSG00000157404 ENSG00000213658 ENSG00000291971 PMC2235195__F1 RA synthesis pathway ENSG00000095596 ENSG00000187553 ENSG00000003137 PMC3236823__F2 Evolution of the mTOR pathway ENSG00000171105 ENSG00000011566 ENSG00000103657 ENSG00000198793 ENSG00000118515 ENSG00000164327 PMC6903684__F1 Tricarboxylic acid cycle enzyme activities in a mouse model of methylmalonic aciduria ENSG00000100412 ENSG00000146701 ENSG00000062485 PMC8706107__F1 HPV16 Entry into Epithelial Cells: Running a Gauntlet ENSG00000067066 ENSG00000164430 ENSG00000111537 ENSG00000176182 ENSG00000140464 PMC7316955__F3 Representative pathways of differentially expressed genes ENSG00000142192 ENSG00000111837 ENSG00000198793 PMC4924657__F8 Double feedback loop mediated by microRNA-23a/27a/24-2 regulates M1 versus M2 macrophage polarization and thus regulates cancer progression ENSG00000137265 ENSG00000113520 ENSG00000118520 PMC4369817__F6 Schematic diagram of the mechanism whereby miR-16 attenuation contributes to myocardial hypertrophy ENSG00000135446 ENSG00000168610 PMC8819183__F3 Comparison of Tendon Development Versus Tendon Healing and Regeneration ENSG00000122877 ENSG00000260428 ENSG00000150051 PMC5412355__F3 The UPR downstream signaling pathway ENSG00000100219 PMC10910709__F9 Platycodon D protects human nasal epithelial cells from pyroptosis through the Nrf2/HO-1/ROS signaling cascade in chronic rhinosinusitis ENSG00000278718 ENSG00000162711 ENSG00000079999 PMC8056081__F2 Diagrams of a hypothesized extreme resistance pathway and its possible relationship to the hypersensitive response ENSG00000281857 ENSG00000134698 PMC8056081__F1 Extreme resistance to viruses in potato and soybean hosts ENSG00000281857 ENSG00000134698 PMC8960923__F1 Estrogen Receptor Complex to Trigger or Delay Estrogen-Induced Apoptosis in Long-Term Estrogen Deprived Breast Cancer ENSG00000157554 ENSG00000198793 PMC9592792__F3 Population‐based meta‐analysis and gene‐set enrichment identifies FXR/RXR pathway as common to fatty liver disease and serum lipids ENSG00000138075 ENSG00000042832 ENSG00000143921 PMC9312706__F2 Drug Repurposing: The Mechanisms and Signaling Pathways of Anti-Cancer Effects of Anesthetics ENSG00000151012 PMC8960923__F2 Estrogen Receptor Complex to Trigger or Delay Estrogen-Induced Apoptosis in Long-Term Estrogen Deprived Breast Cancer ENSG00000128272 ENSG00000144895 ENSG00000168610 PMC9312706__F3 Drug Repurposing: The Mechanisms and Signaling Pathways of Anti-Cancer Effects of Anesthetics ENSG00000198793 PMC9605520__F3 Preclinical and Clinical Research Models of Prostate Cancer: A Brief Overview ENSG00000135437 ENSG00000086696 ENSG00000108786 ENSG00000151632 ENSG00000203859 PMC1052008__F1 Activation of PI3K/Akt signaling in adaptive versus maladaptive hypertrophy ENSG00000198793 PMC5871897__F2 RAS-ERK signaling pathway ENSG00000138798 ENSG00000146648 PMC1052008__F3 GSK-3 as a convergence point in hypertrophic signaling ENSG00000285109 ENSG00000168036 PMC2795439__F1 Androgen-receptor signalling in normal prostate and PCa ENSG00000168610 ENSG00000146648 PMC6539482__F1 The core components of the mammalian Hippo signalling pathway ENSG00000150457 ENSG00000131023 PMC5871897__F5 Colorectal tumorigenesis by both APC and KRAS mutations ENSG00000134982 ENSG00000168036 PMC5871897__F3 Aberrancies of the Wnt/Beta-catenin and RAS-ERK pathways and their cooperation in the tumorigenesis ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000146648 PMC5871897__F4 Wnt/Beta-catenin and RAS-ERK pathway crosstalk ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000138798 ENSG00000168036 ENSG00000146648 PMC7689184__F16 TNFSF15 regulation of antimicrobial pathways ENSG00000167207 ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000057663 ENSG00000007171 PMC5884684__F1 Connections between circadian cycles, C/EBPs and the NAD+-Sirt1 pathway may affect G-CSF induced granulopoiesis ENSG00000245848 ENSG00000096717 PMC5871897__F8 KYA1797K as a potential strategy to overcome resistance to EGFR targeting drugs in CRC ENSG00000159224 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000146648 ENSG00000173273 PMC9046588__F2 Protein Arginine Methylation: An Emerging Modification in Cancer Immunity and Immunotherapy ENSG00000135218 ENSG00000135697 ENSG00000136997 ENSG00000145321 ENSG00000118520 ENSG00000125347 PMC9046588__F3 Protein Arginine Methylation: An Emerging Modification in Cancer Immunity and Immunotherapy ENSG00000070495 ENSG00000126457 ENSG00000172936 ENSG00000175104 PMC7762355__F1 Inflammatory regulation mechanism in a TREM1/2-TLR4-dependent manner in the liver ENSG00000187796 ENSG00000170458 ENSG00000291971 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC9046588__F4 Protein Arginine Methylation: An Emerging Modification in Cancer Immunity and Immunotherapy ENSG00000088888 ENSG00000132600 ENSG00000175104 ENSG00000276561 PMC9046588__F5 Protein Arginine Methylation: An Emerging Modification in Cancer Immunity and Immunotherapy ENSG00000183735 ENSG00000164430 ENSG00000163565 ENSG00000126457 ENSG00000198890 ENSG00000276561 PMC9046588__F6 Protein Arginine Methylation: An Emerging Modification in Cancer Immunity and Immunotherapy ENSG00000128272 ENSG00000134982 ENSG00000136997 ENSG00000115904 ENSG00000168036 ENSG00000198890 PMC6904751__F7 TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKB/VPS34 pathway ENSG00000177169 ENSG00000112561 ENSG00000157954 PMC5705392__F2 Immunobiology of the IL-15-IL-15RA Complex as an Antitumor and Antiviral Agent ENSG00000105639 ENSG00000168610 PMC4336604__F9 How p-CREB acts as a common downstream effector for multiple signaling pathways that regulate BCRP mRNA expression Xie, et.al ENSG00000138798 ENSG00000146648 ENSG00000160741 PMC4019937__F2 Phylogenomic reconstruction of archaeal fatty acid metabolism ENSG00000117322 ENSG00000102977 PMC7914341__F8 PRLR-SF inhibits pentose phosphate pathway through NEK9-YAP/TEAD1-G6PD/TKT axis in PDAC cells PMC4209186__F9 Diabetes Recovery By Age-Dependent Conversion of Pancreatic D-Cells Into Insulin Producers ENSG00000145604 ENSG00000150907 ENSG00000136997 ENSG00000125968 PMC2288663__F6 Nucleotide excision repair pathway ENSG00000012061 ENSG00000108582 ENSG00000132646 ENSG00000136936 PMC7352365__F3 The p53/MDM2 pathway by HERC2 ENSG00000149311 ENSG00000175054 ENSG00000288301 PMC10539948__F1 IFNG signalling pathway ENSG00000173442 ENSG00000115415 ENSG00000198793 PMC6859819__F3 TRK signalling pathway ENSG00000166278 PMC6539482__F3 Interaction between TNFA and the Hippo signalling pathway ENSG00000278268 ENSG00000102871 ENSG00000127191 ENSG00000131023 PMC9640836__F4 PAX5 alterations in B-cell acute lymphoblastic leukemia ENSG00000196092 PMC12183287__F2 BAs contribute to host metabolism in various organs through FXR and TGR5 ENSG00000138075 ENSG00000160867 ENSG00000137077 ENSG00000167910 ENSG00000015520 ENSG00000169710 ENSG00000131096 ENSG00000135929 PMC5806628__F5 Summarization of biological function by a Concept Ontology ENSG00000015285 PMC5861661__F1 p53-dependent cell death pathway ENSG00000149311 PMC6753234__F8 Microbiome–gut–brain axis in relation to AD ENSG00000173599 ENSG00000171759 ENSG00000153395 PMC6162467__F4 CCN2 in regulation of LRP5/6 dependent Wnt signaling ENSG00000168036 PMC4162195__F6 Working model ENSG00000148400 ENSG00000273529 ENSG00000114315 PMC7572679__F2 Metformin modulates lipid metabolism in the intestine, liver, and adipose tissue ENSG00000042832 ENSG00000168958 ENSG00000168036 ENSG00000026103 PMC11791038__F7 FAM210B inhibits the proliferation and metastasis of lung adenocarcinoma via interacting with TOM70 and promoting IFNA/B production ENSG00000213928 ENSG00000088888 ENSG00000115415 ENSG00000124098 PMC2735864__F1 Genetic Variation in TNF and the NFKB Canonical Pathway and Risk of Non-Hodgkin Lymphoma ENSG00000137275 ENSG00000102871 ENSG00000082512 ENSG00000127191 PMC3295195__F10 A novel mechanism linking ROS/Src/caveolin-mediated activation of the EGFR-ERK signaling pathway to chronic Ang II exposure-induced EMT in cultured renal tubular epithelial cells ENSG00000113070 ENSG00000146648 PMC9036252__F1 Two Modulators of Skeletal Development: BMPs and Proteoglycans ENSG00000121989 ENSG00000170365 ENSG00000204217 ENSG00000114739 PMC10950852__F9 Paradigm illustrates the beneficial efficacy of ginseng extracts in modulating circadian rhythm and inflammation ENSG00000008438 ENSG00000167207 ENSG00000105550 ENSG00000132646 ENSG00000136869 PMC8445516__F2 Robinow syndrome-associated genes involved in the WNT/PCP pathway identified in human subjects ENSG00000167693 ENSG00000169071 PMC3722318__F1 Autophagy master regulator TFEB induces clearance of toxic SERPINA1/Alpha-1-antitrypsin polymers ENSG00000100906 ENSG00000112561 PMC7156751__F7 A simplified tumor environment model ENSG00000169245 ENSG00000150782 ENSG00000115415 ENSG00000163739 ENSG00000125538 ENSG00000136869 ENSG00000168610 ENSG00000276561 PMC9496462__F1 Dynamic Regulation of NFKB Response in Innate Immunity: The Case of the IMD Pathway in Drosophila ENSG00000083799 ENSG00000168040 PMC4524510__F2 Cellular FLICE-Like Inhibitory Protein (C-FLIP): A Novel Target for Cancer Therapy ENSG00000102871 ENSG00000168040 ENSG00000026103 PMC2699281__F2 Appetite for destruction: E3 ubiquitin-ligase protection in cardiac disease ENSG00000198625 PMC2699281__F3 Appetite for destruction: E3 ubiquitin-ligase protection in cardiac disease ENSG00000162692 PMC5281639__F1 Induction of interferons (IFNs) and establishment of an antiviral state in a model chicken cell ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000177606 ENSG00000276561 ENSG00000164342 PMC7347488__F1 Renin angiotensin system enzymatic cascade depicting primary receptor systems, biological actions of Angiotensin 2 and Ang-(1–7) and balance between ACE and ACE2 ENSG00000130234 PMC6676786__F2 TGFB family members exhibit distinct effects on heart hypertrophy TGFB binds to its own receptors RII and RI, activates TAK1, SMAD2/3, and p38, and moderately promotes cardiac hypertrophy ENSG00000187871 ENSG00000130513 PMC6676786__F3 The TGFB superfamily in cardiac dysfunction ENSG00000133110 ENSG00000118526 ENSG00000163914 ENSG00000086991 PMC4141540__F7 Schematic model of WNT7B signaling in CRPC cells and osteoblasts ENSG00000188064 PMC7597673__F9 Photoreceptor metabolism cycles between an anaerobic light cycle and an aerobic dark cycle associated with phototransduction through PDE6 activities and mediated by SIRT6 and HIFlA ENSG00000198793 ENSG00000077463 PMC12006985__F3 An overview of TAG synthesis pathway ENSG00000198670 PMC7585830__F3 Positive and negative regulation of Hp (HAMP) transcription and systemic iron homeostasis through the Hp/Fpn signaling pathway ENSG00000261701 ENSG00000178752 ENSG00000168610 ENSG00000127948 PMC7585830__F4 Altered iron homeostasis in breast Cancer Cells and the contribution of their microenvironment ENSG00000111537 ENSG00000170989 ENSG00000142082 ENSG00000168610 ENSG00000283100 PMC7585830__F5 Summary for Inhibitors of the upstream hepcidin signaling: IL-6/IL6R/JAK/STAT3 and BMP/SMAD pathway ENSG00000105697 ENSG00000168610 PMC2857022__F7 Mechanistic model of KLF11-mediated tumor suppression and its antagonism by an oncogenic pathway ENSG00000146648 ENSG00000169375 PMC6581210__F1 Mitochondrial pathways of apoptosis and venetoclax mechanism of action ENSG00000100290 ENSG00000002330 PMC2674698__F1 Structures and metabolic pathway of gangliosides () ENSG00000213614 ENSG00000196743 PMC8875868__F5 Multiple Roles of Glucose-6-Phosphate Dehydrogenase in Tumorigenesis and Cancer Chemoresistance ENSG00000149311 ENSG00000151929 ENSG00000130669 PMC8875868__F6 Multiple Roles of Glucose-6-Phosphate Dehydrogenase in Tumorigenesis and Cancer Chemoresistance ENSG00000158104 ENSG00000100429 ENSG00000128268 PMC8419469__F5 Analysis of Gene Expression Data Incorporating Tumor Purity Information ENSG00000204262 ENSG00000053747 ENSG00000058085 ENSG00000291971 ENSG00000196739 ENSG00000080573 ENSG00000172037 PMC8875868__F7 Multiple Roles of Glucose-6-Phosphate Dehydrogenase in Tumorigenesis and Cancer Chemoresistance ENSG00000124479 ENSG00000198890 PMC2752847__F1 Type I interferon production by dendritic cells in host defense ENSG00000174125 ENSG00000088888 PMC9434059__F1 Specific epigenetic regulators serve as potential therapeutic targets in idiopathic pulmonary fibrosis ENSG00000198742 ENSG00000108821 ENSG00000168610 PMC8632454__F2 Recent and Upcoming Drug Therapies for Pediatric Heart Failure ENSG00000041982 ENSG00000145321 PMC3047627__F3 RECK pathway in stromal–epithelial interaction in prostate cancer ENSG00000100234 ENSG00000087245 ENSG00000157150 ENSG00000149968 ENSG00000157227 ENSG00000100985 PMC6755252__F5 Signaling pathway regulation network of the three validated differentially expressed tRFs ENSG00000140992 ENSG00000281324 ENSG00000169047 ENSG00000102678 ENSG00000196739 ENSG00000157500 ENSG00000148082 ENSG00000155011 ENSG00000138032 ENSG00000115353 ENSG00000196639 ENSG00000196914 ENSG00000180008 ENSG00000077782 ENSG00000155760 ENSG00000140443 ENSG00000282899 ENSG00000157542 ENSG00000136546 ENSG00000166167 ENSG00000143549 ENSG00000182158 ENSG00000109743 ENSG00000140795 ENSG00000198561 ENSG00000158748 ENSG00000284161 ENSG00000065559 ENSG00000152402 ENSG00000171517 ENSG00000100888 ENSG00000102468 ENSG00000101892 ENSG00000140807 ENSG00000156873 ENSG00000163904 ENSG00000106617 ENSG00000110395 ENSG00000170962 ENSG00000145949 ENSG00000063660 ENSG00000163235 ENSG00000175104 ENSG00000146648 ENSG00000187446 ENSG00000291971 ENSG00000169032 ENSG00000118971 ENSG00000065135 ENSG00000145604 ENSG00000161202 ENSG00000171608 PMC10879340__F4 Zebrafish Studies on TGFB Signaling and Pharyngeal Arch Patterning ENSG00000116132 ENSG00000131668 ENSG00000164107 ENSG00000107485 ENSG00000180875 PMC8215710__F1 RIPK1-Associated Inborn Errors of Innate Immunity ENSG00000162711 ENSG00000137275 ENSG00000102871 ENSG00000157625 ENSG00000168040 ENSG00000127191 PMC8739918__F4 Lipopolysaccharide-Induced Transcriptional Changes in LBP-Deficient Rat and Its Possible Implications for Liver Dysregulation during Sepsis ENSG00000169245 ENSG00000111537 ENSG00000136869 ENSG00000156521 ENSG00000109016 PMC9047021__F1 Impacts of MicroRNAs Induced by the Gut Microbiome on Regulating the Development of Colorectal Cancer ENSG00000128191 ENSG00000113360 ENSG00000132341 PMC3849893__F1 Interferon signaling pathway ENSG00000213928 ENSG00000105397 PMC9047021__F2 Impacts of MicroRNAs Induced by the Gut Microbiome on Regulating the Development of Colorectal Cancer ENSG00000177169 ENSG00000172936 ENSG00000136869 PMC3800064__F2 The canonical and noncanonical NFKB pathway ENSG00000104856 ENSG00000173039 ENSG00000131323 PMC1280267__F7 Model schema for the phosphorylation of CRMP-2 by Rho kinase, Cdk5, and GSK-3B ENSG00000010810 ENSG00000163914 ENSG00000133961 ENSG00000075213 PMC9247520__F2 Cryptic Phosphorylation-Mediated Divergent Biosynthesis of High-Carbon Sugar Nucleoside Antifungals ENSG00000144063 ENSG00000101751 ENSG00000122008 PMC9047021__F3 Impacts of MicroRNAs Induced by the Gut Microbiome on Regulating the Development of Colorectal Cancer ENSG00000079387 ENSG00000057663 PMC9047021__F4 Impacts of MicroRNAs Induced by the Gut Microbiome on Regulating the Development of Colorectal Cancer ENSG00000100410 ENSG00000108773 ENSG00000198793 ENSG00000128191 PMC8005608__F3 TRIM-mediated regulation of innate immune signaling pathways ENSG00000162711 ENSG00000106785 ENSG00000167207 ENSG00000112343 ENSG00000113595 ENSG00000119401 ENSG00000204977 ENSG00000137699 ENSG00000146833 ENSG00000171206 ENSG00000121236 ENSG00000169871 ENSG00000141569 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000136869 ENSG00000157625 ENSG00000164342 ENSG00000132109 ENSG00000130159 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000121060 PMC7999520__F8 The signaling pathway by which the neogenin ligand RGMc enhances follicular development ENSG00000127129 PMC2963106__F2 VHL in clear-cell renal cell carcinoma and its relation to targeted therapy ENSG00000162889 ENSG00000198793 ENSG00000146648 ENSG00000114738 PMC4169143__F1 Back to the Future: Oral targeted therapy for RA and other autoimmune diseases ENSG00000169291 ENSG00000198793 ENSG00000167965 PMC6883692__F5 Tobacco-smoking associated genes map to interconnected interferon and stress response signaling networks ENSG00000068079 ENSG00000111961 ENSG00000067066 ENSG00000089127 ENSG00000115415 ENSG00000163568 ENSG00000120868 ENSG00000136826 ENSG00000142166 PMC10151830__F7 Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy ENSG00000117054 ENSG00000169710 PMC6549073__F9 Cisplatin-induced apoptosis in p53-intact and p53-disrupted signaling pathway conditions ENSG00000175054 PMC4625378__F2 Ceramide is the hub of sphingolipid metabolism ENSG00000139624 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000102172 ENSG00000143418 PMC5649420__F2 Integration of Canonical and Noncanonical Pathways in TLR4 Signaling: Complex Regulation of the Wound Repair Program ENSG00000095739 ENSG00000010810 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000146648 PMC4423712__F1 Cardiolipin synthesis and remodeling pathway ENSG00000163624 ENSG00000087157 ENSG00000173599 ENSG00000184207 PMC6497892__F2 Comprehensive overview of the role of Clusterin on apoptosis-related events in cancer cells ENSG00000149311 PMC4637098__F2 Kelch-like chicken erythroid-derived cap “n” collar homology factor-associated protein 1- (Keap1-) NF-E2-related factor 2- (Nrf2) antioxidant response element (ARE) signaling pathway ENSG00000181019 ENSG00000178573 ENSG00000100387 ENSG00000177606 ENSG00000079999 PMC7311391__F6 Overall regulatory networks of miRNAs, circRNAs and mRNAs ENSG00000171791 ENSG00000164305 PMC9450187__F1 Molecular Mechanisms of New Bone Formation in Axial Spondyloarthritis ENSG00000281324 ENSG00000162337 ENSG00000129167 ENSG00000168036 PMC6829950__F7 Summary of SP600125 enhances C-2-induced cell death in bladder cancer cells through resisting JNK- SQSTM1/p62- Nrf2 mediated anti-apoptotic pathway and switching autophagy to apoptosis ENSG00000144848 ENSG00000057663 ENSG00000079999 PMC10853543__F4 SOX TFs acts as the hub of signaling pathways in the tumorigenesis ENSG00000019991 ENSG00000162711 ENSG00000170558 ENSG00000070669 ENSG00000125398 ENSG00000122691 ENSG00000108688 ENSG00000073792 ENSG00000285438 ENSG00000037280 ENSG00000137440 ENSG00000203883 ENSG00000115419 ENSG00000104081 ENSG00000039600 ENSG00000125166 ENSG00000164379 ENSG00000182968 ENSG00000137673 ENSG00000177732 ENSG00000134762 ENSG00000176887 ENSG00000143842 ENSG00000124766 ENSG00000076706 ENSG00000160867 ENSG00000133961 PMC8703482__F2 B Cell Involvement in the Pathogenesis of Ankylosing Spondylitis ENSG00000019582 ENSG00000273686 ENSG00000096717 PMC7923882__F13 Mechanisms for poly(dA:dT)-mediated HSV-2 inhibition in human cervical epithelial cells ENSG00000154451 ENSG00000187608 ENSG00000105397 ENSG00000089127 ENSG00000115415 ENSG00000107201 ENSG00000110324 ENSG00000168610 ENSG00000276561 ENSG00000142166 PMC5576060__F1 Insulin and the PI3K/AKT Signaling Pathway Regulate Ribonuclease 7 Expression in the Human Urinary Tract ENSG00000169047 ENSG00000198793 ENSG00000133124 PMC8675856__F7 Long non‐coding RNAs and their targets as potential biomarkers in breast cancer ENSG00000135801 ENSG00000186526 ENSG00000186529 PMC8675856__F8 Long non‐coding RNAs and their targets as potential biomarkers in breast cancer ENSG00000135801 ENSG00000186526 ENSG00000186529 PMC4865098__F7 Circadian rhythm pathway regulated by CTV-B2, CTV-B6 and CaLas-B232 ENSG00000163435 ENSG00000203783 ENSG00000131188 PMC5642448__F1 Insulin signalling pathway ENSG00000169291 PMC7783402__F2 Role of IIS signaling pathway in reproduction and its longevity Schematic diagram elicits that IIS is actively involved in reproductive function and lifespan in C ENSG00000140992 PMC5378188__F2 Animal NLRs provide structural insights into plant NLR function ENSG00000162711 ENSG00000091106 ENSG00000106100 ENSG00000276068 PMC7775142__F5 Synthetic gene circuits for self-regulated drug delivery systems ENSG00000169245 ENSG00000108691 ENSG00000154736 PMC10867181__F3 Hypoxia regulates the metastatic cascade ENSG00000071564 ENSG00000007168 ENSG00000167772 ENSG00000168036 ENSG00000121966 PMC8430835__F1 Emerging Role of Non-coding RNAs in Drug Resistance of Ovarian Cancer PMC3899918__F2 Jak-STAT Signaling Pathway from KEGG (ID: hsa04630) overlaid with log2 fold change values using PathVisio indicating up (red) or downregulation (blue) following ART ENSG00000110395 PMC6852473__F5 Comparison of central metabolic features of the Rifle comammox Nitrospira PMC8406911__F8 CIRP promotes the progression of non-small cell lung cancer through activation of Wnt/Beta-catenin signaling via CTNNB1 ENSG00000138795 ENSG00000011304 ENSG00000137673 ENSG00000144895 ENSG00000026508 ENSG00000168036 ENSG00000112715 PMC3760419__F4 Cell Death in Disease: Mechanisms and Emerging Therapeutic Concepts ENSG00000168040 ENSG00000026103 PMC4181300__F2 Genetic Factors Associated with Spontaneous Preterm Birth and Pre-Labor Preterm Rupture of Membranes ENSG00000228716 ENSG00000100234 ENSG00000134460 ENSG00000090534 ENSG00000167207 ENSG00000282905 ENSG00000142798 ENSG00000163599 ENSG00000112715 ENSG00000104368 ENSG00000150782 ENSG00000100714 ENSG00000149968 ENSG00000095303 ENSG00000115594 ENSG00000087245 ENSG00000115590 ENSG00000007908 ENSG00000110324 ENSG00000166670 ENSG00000108691 ENSG00000111537 ENSG00000111319 ENSG00000005421 ENSG00000113296 ENSG00000173757 ENSG00000186716 ENSG00000057593 ENSG00000164136 ENSG00000165409 ENSG00000243646 ENSG00000100985 ENSG00000198734 ENSG00000113302 ENSG00000028137 ENSG00000136689 ENSG00000150630 PMC7376555__F4 Schematic model illustrating cellobiose-elicited action of ER stress and lignocellulase synthesis ENSG00000109182 ENSG00000008952 ENSG00000167513 ENSG00000132432 PMC4833515__F3 Oxysterol-Related-Binding-Protein Related Protein-2 (ORP2) Regulates Cortisol Biosynthesis and Cholesterol Homeostasis ENSG00000203859 ENSG00000179142 PMC4181300__F3 Genetic Factors Associated with Spontaneous Preterm Birth and Pre-Labor Preterm Rupture of Membranes ENSG00000115008 ENSG00000110799 ENSG00000143839 ENSG00000166670 ENSG00000007171 ENSG00000104368 ENSG00000117525 ENSG00000111537 ENSG00000038427 ENSG00000170458 ENSG00000184371 ENSG00000028137 ENSG00000140443 ENSG00000026103 PMC9324263__F7 Disruption of O-GlcNAcylation Homeostasis Induced Ovarian Granulosa Cell Injury in Bovine ENSG00000070831 ENSG00000198408 ENSG00000132646 ENSG00000265972 PMC10647353__F4 Unraveling the Potential of miRNAs from CSCs as an Emerging Clinical Tool for Breast Cancer Diagnosis and Prognosis ENSG00000184384 ENSG00000196782 PMC4772349__F2 Candidate driving genetic alterations and their druggability in AYA cancers ENSG00000083857 ENSG00000135446 ENSG00000198793 ENSG00000167986 ENSG00000168036 ENSG00000163132 ENSG00000105810 ENSG00000155903 ENSG00000177084 ENSG00000196712 PMC5660709__F5 Mycobacterium tuberculosis interferes with phagosome maturation ENSG00000102189 ENSG00000198382 ENSG00000135218 ENSG00000184056 ENSG00000119383 ENSG00000168610 PMC3144426__F1 Endoplasmic reticulum (ER) stress and unfolded protein response (UPR) ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC10647353__F2 Unraveling the Potential of miRNAs from CSCs as an Emerging Clinical Tool for Breast Cancer Diagnosis and Prognosis ENSG00000125398 ENSG00000134982 ENSG00000102312 ENSG00000168036 ENSG00000106723 ENSG00000163349 PMC4633016__F3 Schematic diagram showing the convergence of WNT and NOTCH signaling onto cell cycle regulation ENSG00000138795 ENSG00000168214 ENSG00000148400 ENSG00000168036 ENSG00000146648 ENSG00000157240 PMC10647353__F6 Unraveling the Potential of miRNAs from CSCs as an Emerging Clinical Tool for Breast Cancer Diagnosis and Prognosis ENSG00000149311 PMC4528692__F4 ΔNp63 and TAp63 TF networks ENSG00000112561 ENSG00000020633 ENSG00000141968 ENSG00000179862 ENSG00000153814 ENSG00000104903 ENSG00000159216 ENSG00000106571 ENSG00000172216 ENSG00000078900 ENSG00000074181 ENSG00000115112 ENSG00000136997 ENSG00000137203 ENSG00000113430 ENSG00000170921 ENSG00000061337 ENSG00000112182 ENSG00000170549 ENSG00000100721 ENSG00000163884 ENSG00000282899 ENSG00000064195 ENSG00000169594 ENSG00000129194 ENSG00000138795 ENSG00000142192 ENSG00000120837 ENSG00000185022 ENSG00000128886 ENSG00000148400 ENSG00000292149 ENSG00000140968 ENSG00000185669 ENSG00000131196 PMC11534180__F11 Alzheimer's disease pathway modified from the KEGG database [29] ENSG00000132906 ENSG00000177169 ENSG00000142192 ENSG00000171105 ENSG00000123395 ENSG00000134982 ENSG00000156026 ENSG00000198793 ENSG00000148572 ENSG00000133318 ENSG00000115310 ENSG00000168040 ENSG00000281879 ENSG00000127191 ENSG00000164305 ENSG00000102977 ENSG00000291983 ENSG00000128272 ENSG00000119912 PMC11534180__F13 PPI subnetwork of DEGs from HC and EC tissue ENSG00000161016 ENSG00000142541 ENSG00000278270 ENSG00000132639 ENSG00000174444 ENSG00000067715 PMC7492390__F2 Immunological basis of TCMR ENSG00000169245 ENSG00000186810 ENSG00000111537 ENSG00000134982 ENSG00000138755 PMC3257753__F1 TWEAK-Fn14 signaling system ENSG00000082512 ENSG00000175104 ENSG00000127191 PMC7492390__F3 Complement-dependent mechanisms of antibody mediated rejection ENSG00000110799 PMC5732752__F8 Human papillomavirus type 18 E5 oncogene supports cell cycle progression and impairs epithelial differentiation by modulating growth factor receptor signalling during the virus life cycle PMC3815941__F3 Bacterial and host effector molecules with potential probiotic effects ENSG00000226275 ENSG00000239732 PMC11739150__F1 Structures of the insulin/insulin-like growth factor (IGF) system ENSG00000169291 ENSG00000002330 PMC5732388__F3 Key downstream genes were identified in the PLK1 signaling pathway ENSG00000117650 ENSG00000122952 ENSG00000156970 ENSG00000109805 ENSG00000112984 ENSG00000136997 ENSG00000102760 PMC8773933__F2 Bcl-2 Family Proteins in Estrogen Receptor-Positive Breast Cancer and Their Implications in Endocrine Therapy ENSG00000291971 ENSG00000185591 PMC8773933__F3 Bcl-2 Family Proteins in Estrogen Receptor-Positive Breast Cancer and Their Implications in Endocrine Therapy ENSG00000100290 ENSG00000002330 ENSG00000120868 PMC6102046__F6 CNPY2 is a Key Initiator of the PERK-CHOP Pathway of the Unfolded Protein Response ENSG00000128272 ENSG00000144895 ENSG00000257727 PMC5394057__F1 Cellular mechanisms of radioresistance: (I) the cell cycle checkpoint signaling pathway is a critical progress that allowing times for cells to response to repair DNA damage ENSG00000149311 ENSG00000175054 ENSG00000170558 ENSG00000026508 ENSG00000118777 PMC6678780__F4 Protein network analysis of the overexpressed genes in the TLR non-responsive patient cells ENSG00000144028 ENSG00000010803 ENSG00000148444 ENSG00000160299 ENSG00000165804 ENSG00000291582 ENSG00000105393 ENSG00000146247 ENSG00000034677 ENSG00000185658 ENSG00000181555 ENSG00000196470 ENSG00000136709 ENSG00000129351 ENSG00000114857 ENSG00000174501 ENSG00000153107 ENSG00000066117 ENSG00000168283 ENSG00000173894 ENSG00000171456 ENSG00000132004 ENSG00000162402 ENSG00000182473 ENSG00000184634 ENSG00000215375 ENSG00000162521 ENSG00000129534 ENSG00000100888 ENSG00000167986 ENSG00000177200 ENSG00000099326 ENSG00000146021 ENSG00000110987 ENSG00000196465 ENSG00000189079 PMC5732752__F9 Human papillomavirus type 18 E5 oncogene supports cell cycle progression and impairs epithelial differentiation by modulating growth factor receptor signalling during the virus life cycle ENSG00000134057 PMC6804569__F4 Metabolic control of T helper cell differentiation PMC2912031__F4 Reciprocal inhibition mechanism by TGFB and IFNG ENSG00000159128 ENSG00000115415 ENSG00000033800 ENSG00000027697 PMC1175050__F1 NFKB pathway regulates inflammation, dendritic cell (DC) development and function, and thymic selection and regulatory T cell production ENSG00000104856 ENSG00000177606 ENSG00000172936 ENSG00000175104 PMC7414992__F1 LT biosynthesis is part of metabolism of the omega 6 polyunsaturated arachidonic acid (AA), which is cleaved from plasmamembranes by phospholipase A2 (PLA2) ENSG00000226275 PMC4291618__F7 IAV facilitates bacterial adherence through the activation of the TGFB signaling pathway PMC4466627__F1 Ghrelin receptor controls obesity by fat burning ENSG00000121853 PMC8040901__F2 Involvement of the autophagy pathway in the phospholipids of exosomes from LnCap cells (Lipid Pathway Enrichment Analysis, LIPEA) ENSG00000145782 ENSG00000057663 PMC8040901__F3 Lipid Pathway Enrichment Analysis (LIPEA) has shown that the autophagy pathway is involved in the phosphorylation of exosomes from PC3 and DU-145 cells ENSG00000168003 ENSG00000196839 ENSG00000167468 ENSG00000197429 ENSG00000111684 ENSG00000145321 ENSG00000115107 PMC6893734__F6 Schematic representation of the regulation of the autophagy-lysosome system in response to severe energy deficit and its modulation by exercise ENSG00000101901 ENSG00000177169 ENSG00000110497 ENSG00000171791 ENSG00000145782 ENSG00000091140 ENSG00000057663 ENSG00000263238 PMC3949417__F1 Sensing of transferrin-bound iron and regulation of hepcidin expression in hepatocytes ENSG00000170365 ENSG00000010704 PMC8367056__F4 Desmoplakin and clinical manifestations of desmoplakin cardiomyopathy ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC9409255__F3 Restoring TRAILR2/DR5-Mediated Activation of Apoptosis upon Endoplasmic Reticulum Stress as a Therapeutic Strategy in Cancer ENSG00000128272 ENSG00000122484 ENSG00000197930 ENSG00000144895 PMC317132__F1 Model of somatic sex determination in C ENSG00000115884 ENSG00000162512 ENSG00000169439 PMC11641594__F9 Protein–protein interaction (PPI) performed by Ingenuity pathway analysis (IPA) ENSG00000131469 ENSG00000291931 ENSG00000135547 ENSG00000123240 ENSG00000163618 ENSG00000110244 ENSG00000169562 ENSG00000187634 ENSG00000147133 ENSG00000160710 ENSG00000165566 ENSG00000055955 ENSG00000146006 ENSG00000112419 ENSG00000283082 ENSG00000137413 ENSG00000065717 ENSG00000139354 ENSG00000136240 ENSG00000109084 ENSG00000163516 ENSG00000197380 ENSG00000288512 ENSG00000146648 ENSG00000157554 ENSG00000137699 ENSG00000089159 ENSG00000110108 ENSG00000151655 ENSG00000173039 ENSG00000117899 ENSG00000116127 ENSG00000088926 ENSG00000173517 ENSG00000168610 ENSG00000081189 ENSG00000176907 ENSG00000121440 ENSG00000221978 ENSG00000149218 ENSG00000160973 ENSG00000158714 ENSG00000002822 ENSG00000110696 ENSG00000115415 ENSG00000117601 ENSG00000115266 ENSG00000170855 ENSG00000145649 ENSG00000137076 ENSG00000126947 ENSG00000105185 ENSG00000090238 ENSG00000106078 ENSG00000076826 PMC11641594__F7 Apelin signaling pathway with differentially expressed proteins (DEPs) ENSG00000074181 ENSG00000127528 PMC11641594__F8 WNT signaling pathway with differentially expressed proteins (DEPs) ENSG00000087095 ENSG00000095739 ENSG00000100387 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000148175 ENSG00000108375 ENSG00000100211 ENSG00000185269 PMC4480315__F1 Homocysteine metabolism PMC11641594__F5 Human papilloma virus infection pathway with differentially expressed proteins (DEPs) ENSG00000149311 ENSG00000175054 ENSG00000002330 ENSG00000105397 ENSG00000102871 ENSG00000134982 ENSG00000135114 ENSG00000164362 ENSG00000123374 ENSG00000168040 ENSG00000146648 PMC11641594__F6 HIF-1 signaling pathway with differentially expressed proteins (DEPs) ENSG00000134086 ENSG00000198793 ENSG00000072274 ENSG00000136869 ENSG00000168610 PMC1201344__F4 Fasting effects on fatty acid composition ENSG00000083857 ENSG00000165323 PMC3077393__F8 GATA2 Mediates Thyrotropin-Releasing Hormone-Induced Transcriptional Activation of the Thyrotropin B Gene ENSG00000170893 ENSG00000179348 ENSG00000134200 PMC9286923__F4 Metabolic Landscape in Osteoarthritis ENSG00000107779 ENSG00000143799 ENSG00000262406 ENSG00000154736 ENSG00000187531 ENSG00000105835 ENSG00000198793 ENSG00000007171 ENSG00000283100 ENSG00000125398 ENSG00000149968 ENSG00000173599 ENSG00000136997 ENSG00000100985 ENSG00000096717 ENSG00000158859 PMC5835092__F4 Ingenuity Pathway Analysis for the interaction between Jab1/COPS5 and PD-L1 ENSG00000143799 ENSG00000143546 ENSG00000105397 ENSG00000115415 ENSG00000177606 ENSG00000173039 ENSG00000168610 ENSG00000164305 PMC5835092__F5 Ingenuity Pathway Analysis to predict the effect of chemical drugs on level of Jab1/COPS5 ENSG00000143799 ENSG00000109320 ENSG00000177606 ENSG00000168036 ENSG00000168610 PMC7258638__F1 Can respiratory syncytial virus (RSV)-dependent necroptosis be targeted for therapeutic benefit? Simpson and colleagues demonstrate that RSV infection readily induces necroptosis in RSV-infected airway epithelial cells ENSG00000253506 ENSG00000137275 ENSG00000137033 ENSG00000189403 ENSG00000107485 ENSG00000145777 ENSG00000136869 ENSG00000166090 ENSG00000168404 ENSG00000285379 PMC9025423__F1 Head and Neck Cancer Susceptibility and Metabolism in Fanconi Anemia ENSG00000144554 ENSG00000181544 ENSG00000187790 ENSG00000115392 ENSG00000187741 ENSG00000112039 ENSG00000158169 PMC4225589__F5 Plasmalogen-Biosynthesis Pathway and Associated PhenotypesPlasmalogen synthesis is a multistep process that involves several enzymes ENSG00000116906 ENSG00000197601 PMC4751407__F1 Disc in Flames: Roles of TNFA and IL-1B in Intervertebral Disc Degeneration ENSG00000102871 ENSG00000056558 ENSG00000131323 ENSG00000168040 ENSG00000127191 PMC5835092__F3 Ingenuity Pathway Analysis (IPA) for Jab1/COPS5 regulation network in cancer ENSG00000100906 ENSG00000109320 ENSG00000177606 ENSG00000168036 ENSG00000171791 ENSG00000168610 ENSG00000146648 PMC4666639__F6 Fn14, a Downstream Target of the TGFB Signaling Pathway, Regulates Fibroblast Activation PMC3656404__F1 Signaling pathways involving PKR-mediated inflammation and immune regulation ENSG00000144895 ENSG00000163568 ENSG00000189403 ENSG00000091106 PMC9604018__F7 Pharmacological and Therapeutic Applications of Esculetin ENSG00000150907 ENSG00000169710 ENSG00000062282 PMC8616597__F3 Transcriptome analysis reveals disruption of circadian rhythms in late gestation dairy cows may increase risk for fatty liver and reduced mammary remodeling ENSG00000179094 PMC5292181__F5 Functional interaction network analysis by GeneMANIA of candidate mouse and human genes related to brain metastasis ENSG00000107562 ENSG00000151012 ENSG00000073111 ENSG00000102468 ENSG00000121966 ENSG00000186827 ENSG00000118160 ENSG00000111602 ENSG00000180061 ENSG00000156802 ENSG00000004864 ENSG00000139304 ENSG00000139287 ENSG00000163794 ENSG00000102934 ENSG00000100479 ENSG00000163634 ENSG00000100154 ENSG00000162692 ENSG00000177084 ENSG00000038945 PMC4145387__F2 E-cadherin regulated signaling pathways involved in gastric cancer ENSG00000138795 ENSG00000137673 ENSG00000070831 ENSG00000163914 ENSG00000026508 ENSG00000168036 ENSG00000146648 PMC4468369__F7 Illustration for the mechanism underlying s-IL-15RA–induced EMT, migration, and invasion of human RCCs ENSG00000291971 ENSG00000168036 PMC4339202__F6 Metabolic and Chaperone Gene Loss Marks the Origin of Animals: Evidence for Hsp104 and Hsp78 Chaperones Sharing Mitochondrial Enzymes as Clients ENSG00000166123 ENSG00000143669 PMC7352628__F7 CIGB-300-mediated effects on T-ALL cells ENSG00000105639 ENSG00000168685 PMC6467053__F2 Signal Transduction pathway for STAT3 ENSG00000115415 ENSG00000168610 PMC4326486__F4 Proposed model is that CD146 promotes angiogenesis and mesenchymal cell migration in melanoma ENSG00000004975 ENSG00000162772 PMC185249__F3 Sprouty is a rapidly inducible negative regulator of fibroblast growth factor (FGF) pathway signaling ENSG00000136158 PMC7980828__F4 Flavivirus; entry, life cycle, and immune system interaction: (A) Flavivirus infections are generally transmitted through the bite of an infected mosquito or tick ENSG00000188379 ENSG00000140564 ENSG00000115415 ENSG00000276561 PMC185249__F4 Signal transduction in the Transforming Growth Factor B(TGFB) family pathway is finely regulated at many levels ENSG00000157933 ENSG00000138798 ENSG00000163914 ENSG00000156574 PMC8762717__F9 PKA and Epac1 Reduce Nek7 to Block the NLRP3 Inflammasome Proteins in the Retinal Vasculature ENSG00000162711 ENSG00000125538 PMC5884924__F9 White adipose tissue browning through reducing tenascin C inflammatory signaling ENSG00000162711 ENSG00000170365 ENSG00000041982 ENSG00000106004 ENSG00000136869 PMC6731062__F3 Proteins in the glycolysis, tricarboxylic acid, and oxidative phosphorylation pathways examined by the Ingenuity Pathway Analysis software ENSG00000105664 ENSG00000073578 ENSG00000196839 ENSG00000117118 PMC3534995__F2 Canonical pathway representing LPS/IL-1-mediated inhibition of RXR function obtained by IPA from the analysis of HT29 data set ENSG00000170458 ENSG00000197408 ENSG00000136869 PMC4697050__F3 Signaling pathway of BDNF ENSG00000002330 PMC3534995__F3 Canonical pathway representing NRF2-mediated oxidative stress response obtained by IPA from the analysis of SW480 data set ENSG00000128272 ENSG00000178573 ENSG00000100387 ENSG00000177606 ENSG00000095015 ENSG00000175592 ENSG00000197442 ENSG00000166484 ENSG00000169032 ENSG00000135341 ENSG00000137764 ENSG00000079999 PMC2947266__F10 The signaling transduction pathway leading to tPA induced fibroblast proliferation PMC4496222__F7 Shp2 SUMOylation promotes ERK activation and hepatocellular carcinoma development ENSG00000146648 PMC4003867__F1 Emerging role of Interleukin-22 in autoimmune diseases ENSG00000105397 ENSG00000115415 ENSG00000168610 PMC8517511__F2 CBX7 is Dualistic in Cancer Progression Based on its Function and Molecular Interactions ENSG00000168283 ENSG00000134982 ENSG00000196591 ENSG00000008083 PMC8602812__F3 Meta-Inflammation and Metabolic Reprogramming of Macrophages in Diabetes and Obesity: The Importance of Metabolites ENSG00000131473 ENSG00000177575 ENSG00000084774 PMC8602812__F4 Meta-Inflammation and Metabolic Reprogramming of Macrophages in Diabetes and Obesity: The Importance of Metabolites ENSG00000131473 ENSG00000135218 ENSG00000047936 ENSG00000084774 PMC6975965__F4 ERBB2 signaling depicting actionable targets ENSG00000065361 ENSG00000198793 ENSG00000146648 PMC3756346__F2 Map of the molecular mechanisms of apoptosis ENSG00000132906 ENSG00000002330 ENSG00000102871 ENSG00000168040 ENSG00000115317 ENSG00000026103 ENSG00000276068 PMC9484255__F4 Treating ARID1A mutated cancers by harnessing synthetic lethality and DNA damage response ENSG00000117713 ENSG00000149311 ENSG00000175054 ENSG00000164430 PMC9237231__F4 Regulation and Modification of GSDMD Signaling in Diseases ENSG00000278718 ENSG00000132109 ENSG00000131669 ENSG00000137275 ENSG00000168040 PMC4090452__F2 Integration of the proposed pathways by which the NTPDase5/mt-PCPH acts on the neoplastic progression ENSG00000198793 PMC7515865__F3 PI3K/AKT pathway as a key link modulates the multidrug resistance of cancers ENSG00000002330 ENSG00000198793 PMC7515865__F1 PI3K/AKT pathway as a key link modulates the multidrug resistance of cancers ENSG00000186716 PMC4070062__F3 Cytosolic nucleic acids sensors and autophagy ENSG00000123576 ENSG00000164430 PMC4070062__F1 TLRs and autophagy ENSG00000239732 ENSG00000167207 ENSG00000172936 ENSG00000136869 ENSG00000106100 ENSG00000276561 PMC3971994__F1 HGF/Met receptor signaling pathway ENSG00000019991 PMC3858246__F1 Canonical WNT/Beta-catenin signaling and inhibitors ENSG00000134982 ENSG00000168036 PMC8640016__F8 FUT8 negatively regulates NFKB2 signaling by blocking the activation of TNFR ENSG00000077150 ENSG00000140379 ENSG00000168040 PMC8947839__F4 Forkhead Box Protein O1 (FoxO1) in Stroke: A Literature Review ENSG00000150907 ENSG00000125538 ENSG00000100985 PMC5259907__F2 The network of cell apoptosis regulation induced by DNA damage ENSG00000149311 ENSG00000175054 PMC5259907__F4 Network constructed based on ENSG00000149311 ENSG00000132906 ENSG00000150907 ENSG00000136997 ENSG00000168040 ENSG00000146648 ENSG00000064012 ENSG00000164305 PMC7687032__F3 Blood–brain barrier integrity by microglia in health and disease: A therapeutic opportunity ENSG00000198793 PMC3510123__F7 Eliminating the SLAC1 anion channel affects K+ channel activity, K+ uptake, and the rate of stomatal opening through its impact on and as predicted by the OnGuard model (; ) ENSG00000172005 PMC3652804__F1 Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity ENSG00000140992 ENSG00000171105 ENSG00000112964 ENSG00000169047 ENSG00000121879 ENSG00000160691 ENSG00000117020 ENSG00000115457 ENSG00000167779 ENSG00000141753 ENSG00000133124 ENSG00000146678 ENSG00000115461 PMC5749725__F2 Identification of metastasis driver genes by massive parallel sequencing of successive steps of breast cancer progression ENSG00000087095 ENSG00000159224 ENSG00000171105 ENSG00000136153 ENSG00000171540 ENSG00000140443 PMC9393500__F1 Biosynthetic approaches to efficient assimilation of CO2 via photorespiration modification in plant chassis ENSG00000178922 PMC10932467__F2 Possible effects of IL-6 signaling on energy intake and energy expenditure under non-obesogenic conditions ENSG00000149311 ENSG00000168610 PMC4508517__F4 Uses of CRY2 domains PMC8635802__F4 Kinase Inhibition as Treatment for Acute and Chronic Graft-Versus-Host Disease ENSG00000134982 ENSG00000124181 PMC2911016__F1 “Go upstream, young man”: lessons learned from the p38 saga ENSG00000162889 PMC2921576__F1 Schematic representation of hepatic methionine metabolism PMC5508527__F2 Metabolic reprogramming and tolerance during sepsis-induced AKI ENSG00000077463 ENSG00000096717 PMC6001073__F5 The gene or protein expression of GLUT1, HK1, PGM1, UGP2, GALT, GALE, SLC35A2, LALBA, and B4GALT1 on the lactose synthesis pathway throughout lactation ENSG00000069482 ENSG00000292209 PMC5508527__F3 Metabolic reprogramming and tolerance during sepsis-induced AKI ENSG00000077463 ENSG00000096717 PMC5988853__F2 Interplays of interleukin-23 (IL-23), IL-6, signal transducer and activator of transcription 3 (STAT3), and retinoid-related orphan receptor Gt (RORGt) in the differentiation of pathogenic T helper 17 (Th17) cells ENSG00000105397 ENSG00000168610 ENSG00000115009 ENSG00000112486 PMC8160894__F6 TAK1/AP-1-Targeted Anti-Inflammatory Effects of Barringtonia augusta Methanol Extract ENSG00000108691 ENSG00000172936 ENSG00000136869 PMC6608034__F3 MTORC1 pathway: effect on TLR signaling cascades and modulation by bacteria ENSG00000172936 ENSG00000168610 PMC3073693__F4 Molecular pathways in dystonia ENSG00000144895 ENSG00000131931 PMC11880140__F2 Roles of five types of decidual innate immune cells in the regulation of labor initiation and PTB ENSG00000166349 PMC7265991__F1 Intersection of radiation and the tumor immune microenvironment ENSG00000164430 ENSG00000135218 ENSG00000189403 PMC3328908__F9 Diagram of canonical tight junction signaling pathway ENSG00000147044 PMC3670239__F1 Infection-induced IL-10 and JAK-STAT ENSG00000105397 ENSG00000170458 ENSG00000115415 ENSG00000168610 PMC8422077__F2 Depiction of genetic dependencies in cancer ENSG00000132612 ENSG00000119541 ENSG00000157764 ENSG00000138798 ENSG00000146648 PMC8834883__F1 Therapeutic Action of Autophagy in Gastric Cancer Managements: Novel Treatment Strategies and Pharmacological Interventions ENSG00000177169 ENSG00000083290 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC8001445__F4 Metabolomic map of flor yeast gluconic acid consumption ENSG00000159224 ENSG00000122966 ENSG00000173599 ENSG00000172005 PMC8834883__F3 Therapeutic Action of Autophagy in Gastric Cancer Managements: Novel Treatment Strategies and Pharmacological Interventions ENSG00000126775 ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC6529190__F10 Adiponectin-mediated signaling pathway in HSCs ENSG00000157500 ENSG00000088305 ENSG00000159346 ENSG00000285070 PMC7662373__F1 The hypoxia pathway under normoxia and hypoxia ENSG00000134086 ENSG00000168610 PMC6027421__F2 Steroid biosynthetic pathway PMC8427689__F6 Integrating Network Pharmacology and Experimental Verification to Explore the Mechanism of Effect of Zuojin Pills in Pancreatic Cancer Treatment ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000169291 ENSG00000002330 ENSG00000069482 ENSG00000186716 PMC11747879__F2 Activin signalling pathway ENSG00000070404 PMC4156532__F9 Sestrin2 Promotes Unc-51-like Kinase 1 (ULK1)-Mediated Phosphorylation of p62/sequestosome-1 ENSG00000177169 ENSG00000183735 ENSG00000285069 ENSG00000079999 PMC11894105__F2 Molecular mechanisms of apoptosis pathway activation ENSG00000102871 ENSG00000168040 ENSG00000026103 PMC4942281__F2 Oncogenic survival signaling components in PCNSL ENSG00000107562 ENSG00000186716 ENSG00000136997 ENSG00000137193 ENSG00000113520 ENSG00000172936 ENSG00000136869 ENSG00000171791 ENSG00000168610 ENSG00000184216 ENSG00000010671 PMC11894105__F3 TNF-induced necroptosis signaling pathway ENSG00000102871 ENSG00000082512 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 PMC7023707__F1 Kynurenine pathway and tryptophan metabolism in the central nervous system PMC12183064__F6 Molecular mechanism of ERA36-mediated protection against HG-induced apoptosis and senescence ENSG00000164305 PMC6426753__F1 Complement pathways ENSG00000203710 ENSG00000000971 ENSG00000166278 ENSG00000182326 ENSG00000062485 PMC3890654__F1 Toll-like receptor-4 signaling pathway ENSG00000170458 ENSG00000177606 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000185187 ENSG00000175104 PMC3890654__F2 Negative regulators of toll-like receptor-4 signaling pathway by Lactobacillus jensenii TL2937 in porcine intestinal epithelial cells and antigen presenting cells ENSG00000170458 ENSG00000177606 ENSG00000172005 ENSG00000157625 ENSG00000136869 ENSG00000185187 PMC7865493__F1 Aryl hydrocarbon receptor (AhR) signaling pathways: canonical (A) and noncanonical (B) ENSG00000125538 ENSG00000146648 ENSG00000106546 PMC11894105__F5 Molecular mechanisms and regulatory networks of ferroptosis ENSG00000167468 ENSG00000111684 ENSG00000115107 PMC7865493__F2 Molecular interactions within the AhR signaling pathway ENSG00000181019 ENSG00000172818 ENSG00000140465 ENSG00000143631 ENSG00000106546 PMC6620896__F3 Conceptual model of cellular processes within Tv ENSG00000004848 PMC12160515__F2 Possible signaling pathways in inflammatory-oxidative stress mediated neural regeneration ENSG00000002330 ENSG00000079999 PMC3393719__F8 Yeast Magmas Ortholog Pam16 Has an Essential Function in Fermentative Growth That Involves Sphingolipid Metabolism ENSG00000215021 ENSG00000164105 PMC6027492__F2 Mitochondrial protein lipoylation ENSG00000121897 ENSG00000144182 ENSG00000291958 ENSG00000175536 ENSG00000026103 PMC4459582__F7 Kruppel-like factor 5 is required for perinatal lung morphogenesis and function ENSG00000066468 ENSG00000123612 ENSG00000135409 ENSG00000156427 ENSG00000095303 ENSG00000134853 ENSG00000204217 PMC4905194__F2 Mechanisms of gap filling ENSG00000132646 ENSG00000070950 ENSG00000051180 ENSG00000178966 ENSG00000177084 PMC4828451__F5 Complement activation pathways ENSG00000039537 ENSG00000113600 ENSG00000291559 ENSG00000203710 ENSG00000244731 ENSG00000166278 PMC6549747__F1 Signaling pathways implicated in different categories of breast cancer ENSG00000157404 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000077782 ENSG00000146648 ENSG00000140443 PMC6549747__F2 Interaction between tumor microenvironment components, including stromal cells, and tumor cells leads to enhanced cell growth, proliferation, angiogenesis and invasion ENSG00000135446 ENSG00000136997 ENSG00000105810 PMC4682245__F5 DEGs involved in JNK pathway in Tg(RE:HSE:EGFP) ENSG00000130522 ENSG00000081189 PMC4772696__F3 Role of EZH2 in genomic signaling through canonical and non-canonical activity ENSG00000074266 ENSG00000178691 PMC3819741__F2 Identification of the genes in the MAPK signaling pathway that harbor or are in the close proximity of SNPs associated with feed efficiency ENSG00000170458 ENSG00000177606 ENSG00000130159 ENSG00000116096 ENSG00000026103 PMC4084561__F2 Regulation of type I interferon responses ENSG00000105397 ENSG00000115415 ENSG00000138755 ENSG00000157601 ENSG00000125347 ENSG00000168610 ENSG00000169375 ENSG00000142166 PMC4084561__F3 Regulation of type I interferon responses ENSG00000184979 ENSG00000105397 ENSG00000115415 ENSG00000123908 PMC2842130__F9 Redoxosomal signaling for IL-1B and TNFA pathways ENSG00000102871 ENSG00000172936 ENSG00000175104 ENSG00000127191 ENSG00000115594 PMC3236512__F2 Effect of FXR activation on triglyceride and cholesterol metabolism in the liver ENSG00000138075 ENSG00000130164 ENSG00000042832 ENSG00000005421 ENSG00000113161 ENSG00000169174 ENSG00000143921 PMC8654299__F1 CoQ biosynthetic pathway of plant and the coexpression network ENSG00000132423 ENSG00000167113 ENSG00000119723 ENSG00000110871 ENSG00000088682 ENSG00000197429 ENSG00000173085 PMC3151543__F2 Schematic depiction of how complement modulates T-cell immunity ENSG00000134982 ENSG00000171791 ENSG00000026103 PMC4505959__F10 The molecular events leading to the production of IL-10 in macrophages exposed to S ENSG00000077150 ENSG00000130414 ENSG00000100412 ENSG00000159322 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC2924648__F3 Directed cell migration ENSG00000134982 ENSG00000149269 ENSG00000146648 PMC7644914__F1 The underlying molecular mechanisms influencing the protein synthesis, degradation, and dynamic trafficking processes of ASIC1a ENSG00000125538 PMC3513219__F2 XRCC1 is instrumental in base excision repair (BER) of small oxidative lesions and a related mechanism for the repair of single-strand breaks (SSB-R), both caused by ionizing radiation ENSG00000039650 PMC12174687__F3 Nectin-4 signaling in normal and malignant cells ENSG00000107562 ENSG00000181847 ENSG00000170558 ENSG00000121966 PMC6217754__F1 IL-32-induced signaling pathway activation in macrophages ENSG00000081041 ENSG00000163739 ENSG00000168610 PMC7820759__F4 Schematic view of the molecular network and functions of human papillomavirus (HPV) E5, E6, and E7 oncoproteins in HPV-induced cancers ENSG00000147162 ENSG00000135446 ENSG00000142453 ENSG00000126457 ENSG00000109062 ENSG00000123374 ENSG00000205250 ENSG00000105810 ENSG00000132510 ENSG00000168610 ENSG00000146648 PMC4867367__F4 GR cross talk with the TLR signaling pathway ENSG00000183735 ENSG00000172005 ENSG00000196591 ENSG00000134070 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000155974 ENSG00000184216 PMC5777349__F9 SEC-induced activation of ANXA7 GTPase suppresses prostate cancer metastasis ENSG00000108691 ENSG00000168610 ENSG00000171388 PMC6949885__F15 Molecular mechanism by which miR-601 downregulation inhibits the proliferation, migration and invasion of PCSCs by activating KRT5, and subsequently inhibiting the Wnt signaling pathway ENSG00000168036 ENSG00000125084 PMC5296320__F2 Schematic representation of the role of pancreastatin (PST) in the regulation of insulin secretion from pancreatic beta cells ENSG00000145321 ENSG00000047932 PMC4867367__F5 Cross talk of GR with the STAT signaling pathway ENSG00000291971 ENSG00000168610 PMC6103460__F1 Major Nai influx and efflux pathways and metabolic pathways involved in ATP supply ENSG00000157184 ENSG00000196531 ENSG00000135218 ENSG00000156026 PMC5932189__F3 Myeloid C-type lectins and heterologous receptors ENSG00000187796 ENSG00000198793 ENSG00000172936 ENSG00000125347 PMC8830302__F1 Next steps for clinical translation of adenosine pathway inhibition in cancer immunotherapy ENSG00000089692 ENSG00000111537 ENSG00000163599 ENSG00000049768 PMC6430726__F7 Down-regulation of miR-543 expression increases the sensitivity of colorectal cancer cells to 5-Fluorouracil through the PTEN/PI3K/AKT pathway ENSG00000171791 PMC3532179__F1 Mathematical model of the apoptotic pathways induced by cisplatin ENSG00000132906 ENSG00000175054 ENSG00000164305 PMC8000754__F4 Proteasome inhibitors and metabolic pathways ENSG00000128272 ENSG00000105835 ENSG00000142082 PMC11120609__F1 Metabolic pathway of cyclophosphamide ENSG00000165841 ENSG00000197408 PMC9389016__F7 Integrated network pharmacology and hepatic metabolomics to reveal the mechanism of Acanthopanax senticosus against major depressive disorder ENSG00000291507 ENSG00000068976 PMC11552210__F2 Molecular pathways involved in the increase of fibrosis in the ovary and uterus by exposure to micro/nano plastics ENSG00000087245 ENSG00000189403 ENSG00000136869 ENSG00000100985 PMC3978192__F2 Pathophysiology and pharmacology of hepcidin ENSG00000170365 ENSG00000010704 ENSG00000106327 ENSG00000168610 PMC6306333__F5 Proposed working model ENSG00000125538 ENSG00000169429 PMC6982102__F2 Ceramide is the central molecule in sphingolipid metabolism and can be synthesized by three different pathways: de novo synthesis pathway, sphingomyelinase pathway and salvage pathway ENSG00000100422 ENSG00000128052 ENSG00000102172 PMC3575845__F7 Anti-quiescence network mediated by the Myc-miR-22 pathway ENSG00000138380 ENSG00000123933 ENSG00000136997 ENSG00000164938 ENSG00000189403 PMC8025348__F2 Main mechanism of F ENSG00000181847 ENSG00000125538 ENSG00000168036 ENSG00000136869 PMC5111721__F3 NAD+ metabolism is compartmentalized ENSG00000105835 ENSG00000157064 ENSG00000124523 ENSG00000077463 ENSG00000173614 ENSG00000096717 ENSG00000142082 ENSG00000089163 ENSG00000283100 PMC4695008__F6 Infiltrating bone marrow mesenchymal stem cells (BM-MSCs) increase prostate cancer cell invasion via altering the CCL5/HIF2A/androgen receptor signals ENSG00000134086 ENSG00000121966 PMC1952649__F2 Two tales concerning skeletal muscle PMC11760605__F2 This diagram represents a schematic overview of the MAPK pathway, comprising three principal activation branches: RTK, ERK, JNK activation nodes ENSG00000162889 ENSG00000115415 ENSG00000089022 ENSG00000114738 PMC8208723__F10 Root meristem size reduction and stem cell death in response to DSBs ENSG00000149311 ENSG00000127445 ENSG00000102309 PMC8102120__F1 Pyroptosis: A New Frontier in Kidney Diseases ENSG00000278718 ENSG00000162711 ENSG00000163568 PMC3538647__F1 Metabolic map of the purine biosynthetic pathway ENSG00000185129 ENSG00000146676 PMC6688195__F1 Key intrinsic immune evasion mechanisms exploited by HPV oncoproteins in keratinocytes (KCs) ENSG00000145824 ENSG00000151376 ENSG00000158473 ENSG00000213928 ENSG00000239732 ENSG00000164430 ENSG00000115415 ENSG00000131323 PMC5935098__F3 Hippo Signaling Circuit and Divergent Tissue Growth in Mammalian Eye ENSG00000186575 ENSG00000197713 PMC8380402__F10 NCAPG promotes the progression of lung adenocarcinoma via the TGFB signaling pathway ENSG00000109805 ENSG00000170558 PMC3882710__F8 The potential role of MuRF1 in atrophy induced gene expression pathways ENSG00000122180 ENSG00000108515 ENSG00000100344 ENSG00000081189 PMC3674015__F1 (A–C) Schematic overview of particle-based vaccines PMC8908994__F2 Noncoding RNAs in Cardiac Hypertrophy and Heart Failure ENSG00000285109 ENSG00000078399 ENSG00000116688 ENSG00000263528 ENSG00000225190 ENSG00000172936 PMC4305955__F1 Fibronectin-related signaling pathway graph stored in HBVPathDB ENSG00000291971 ENSG00000163914 PMC3248179__F2 Evi1 forms a bridge between the epigenetic machinery and signaling pathways ENSG00000005882 PMC4331626__F4 Depiction of various pathways that are known to contribute to eEF2K regulation in systems biology graphical notation (SBGN) activity flow format () ENSG00000284161 ENSG00000167658 PMC8298820__F2 Glycyrrhizic Acid: A Natural Plant Ingredient as a Drug Candidate to Treat COVID-19 ENSG00000130234 ENSG00000189403 PMC9367289__F1 Molecular Pathways and Genomic Landscape of Glioblastoma Stem Cells: Opportunities for Targeted Therapy ENSG00000164690 ENSG00000128602 PMC5903825__F1 Hepcidin regulation and action in non-cancerous tissue ENSG00000010704 ENSG00000106327 ENSG00000178752 PMC4128256__F7 Models of Ras signaling in NF1-deficient GBM cell lines ENSG00000198793 ENSG00000196712 PMC2593023__F1 Unexpected pieces to the senescence puzzle ENSG00000157764 ENSG00000163453 PMC4598780__F1 DNA damage response activates cell cycle checkpoint ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000116717 ENSG00000101224 PMC5325323__F3 Neural tube closure: cellular, molecular and biomechanical mechanisms ENSG00000170365 ENSG00000164690 PMC8156813__F5 Sildenafil Alleviates Murine Experimental Autoimmune Encephalomyelitis by Triggering Autophagy in the Spinal Cord ENSG00000198793 ENSG00000057663 PMC8998017__F1 STING Agonists/Antagonists: Their Potential as Therapeutics and Future Developments ENSG00000164430 ENSG00000197594 PMC9103444__F3 Mechanisms of lncRNA-Mediated Multidrug Resistance and the Clinical Application Prospects of lncRNAs in Breast Cancer PMC6385449__F13 miR-506 inhibited the expression of LHX2, which hampered TCF4 expression and inactivated the Wnt/Beta-catenin signaling pathway, consequently inhibiting tumor growth and metastasis in NPC ENSG00000168036 ENSG00000196628 PMC11673094__F7 Targeting to insulin resistance is illustrated and summarized ENSG00000169047 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC9103444__F8 Mechanisms of lncRNA-Mediated Multidrug Resistance and the Clinical Application Prospects of lncRNAs in Breast Cancer ENSG00000167258 PMC5944225__F9 Magnoliae Cortex and maize modulate Porphyromonas gingivalis-induced inflammatory reactions ENSG00000125538 ENSG00000168610 PMC11673094__F5 Targeting to maintain mitochondrial function is illustrated and summarized ENSG00000143799 ENSG00000116688 ENSG00000096717 ENSG00000171109 PMC10490091__F7 Anti-Inflammatory Effect of Meriania hexamera Sprague by Targeting Syk Kinase in NFKB Signaling ENSG00000291971 ENSG00000172936 ENSG00000136869 PMC11673094__F3 Targeting to attenuate the inflammation is illustrated and summarized ENSG00000162711 ENSG00000125538 ENSG00000086991 ENSG00000172936 ENSG00000136869 ENSG00000265972 ENSG00000163661 ENSG00000175104 ENSG00000074842 ENSG00000123983 PMC11673094__F4 Targeting to attenuate the ROS is illustrated and summarized ENSG00000086991 ENSG00000142082 PMC11673094__F1 Potential molecular pathways of fatty acid, especially PA-induced vascular endothelial dysfunction, are illustrated and summarized—PA uptake by endothelial cells through fatty acid transporter or passive diffusion ENSG00000143799 ENSG00000162711 ENSG00000116688 ENSG00000169047 ENSG00000086991 ENSG00000172936 ENSG00000136869 ENSG00000163661 ENSG00000175104 ENSG00000171109 PMC8684233__F3 Ferroptosis in urologic malignancies ENSG00000167468 ENSG00000198793 PMC5022081__F1 Post-translation processing of Klotho protein ENSG00000137845 ENSG00000062485 PMC8660617__F9 Prognostic and immune infiltration signatures of proteasome 26S subunit, non-ATPase (PSMD) family genes in breast cancer patients ENSG00000145604 ENSG00000068028 ENSG00000149311 ENSG00000175054 ENSG00000094804 ENSG00000134982 ENSG00000123374 ENSG00000166851 ENSG00000117399 ENSG00000139618 PMC11673094__F2 Targeting to attenuate the programmed cell death is illustrated and summarized ENSG00000162711 ENSG00000163661 ENSG00000096717 PMC3338196__F3 Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation ENSG00000122966 ENSG00000173599 ENSG00000172005 PMC2972986__F1 Biological processes known to be stimulated in an AHR-dependent and/or AHR-independent manner by the tryptophan photoproduct FICZ ENSG00000140465 ENSG00000106546 PMC3839581__F1 Insulin Biosynthetic Interaction Network Component, TMEM24, Facilitates Insulin Reserve Pool Release ENSG00000187664 ENSG00000204842 ENSG00000159224 ENSG00000123416 ENSG00000104093 ENSG00000147485 ENSG00000134982 ENSG00000140575 ENSG00000104368 ENSG00000151914 ENSG00000198947 ENSG00000198951 ENSG00000163539 ENSG00000242247 ENSG00000157617 ENSG00000110841 ENSG00000175166 ENSG00000082805 ENSG00000197879 ENSG00000170632 ENSG00000116584 ENSG00000127824 ENSG00000130508 ENSG00000173692 ENSG00000090520 ENSG00000074054 ENSG00000152556 PMC4963802__F1 Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000133067 ENSG00000108375 PMC11475825__F4 IPA analysis of the signaling networks between AhR signaling and NRF2 signaling ENSG00000140505 ENSG00000140465 ENSG00000124762 ENSG00000106546 PMC1774670__F2 Interaction of JC virus (JCV) T-antigen with key growth regulatory pathways ENSG00000169047 ENSG00000168036 PMC10310980__F1 Circadian clocks in cancer: Mechanisms and clinical implications ENSG00000198793 ENSG00000116791 ENSG00000145321 ENSG00000026508 PMC5547743__F7 Proposed model for I-SMAD-regulated signaling that enhances HSPG expression, cholesterol uptake and HCV entry ENSG00000137834 ENSG00000130164 ENSG00000110651 ENSG00000146648 PMC1774670__F6 P53 pathway ENSG00000132646 PMC11475825__F2 Actin mechanism of the NRF2 signaling pathway ENSG00000148400 ENSG00000167468 ENSG00000140044 ENSG00000115657 ENSG00000023909 ENSG00000136826 PMC4257089__F1 In silico modeling of a CD4+ T-cell ENSG00000142192 ENSG00000171105 ENSG00000070831 ENSG00000291971 ENSG00000102010 ENSG00000073756 ENSG00000196396 ENSG00000064300 ENSG00000010671 ENSG00000160691 ENSG00000179295 ENSG00000129219 ENSG00000162139 ENSG00000213658 ENSG00000113263 ENSG00000146648 PMC9250486__F4 Aspirin sensitivity of PIK3CA-mutated Colorectal Cancer: potential mechanisms revisited ENSG00000198793 ENSG00000168036 PMC5571780__F1 Small GTPases in endothelial barrier regulation ENSG00000157927 ENSG00000168036 PMC5869671__F1 NF-kB2 Genetic Variations are Significantly Associated with Non-Small Cell Lung Cancer Risk and Overall Survival ENSG00000104856 ENSG00000107862 ENSG00000107872 ENSG00000111321 PMC2945208__F1 KEEPING AN EYE ON RETINOBLASTOMA CONTROL OF HUMAN EMBRYONIC STEM CELLS ENSG00000123374 ENSG00000105810 PMC2945208__F3 KEEPING AN EYE ON RETINOBLASTOMA CONTROL OF HUMAN EMBRYONIC STEM CELLS ENSG00000112242 ENSG00000123374 ENSG00000105810 PMC1959234__F1 Schematic model for the "error-free" BRCA double strand break repair pathway Brief overview of components within the BRCA pathway used here as a working model that was tested here ENSG00000149311 ENSG00000012048 ENSG00000139618 ENSG00000183765 PMC11703838__F2 Signaling pathways in TCSCs ENSG00000106571 ENSG00000283780 ENSG00000134982 ENSG00000166813 ENSG00000004487 ENSG00000168036 ENSG00000128602 ENSG00000168610 PMC8722734__F3 Long Noncoding RNA 00472: A Novel Biomarker in Human Diseases ENSG00000150907 ENSG00000158796 ENSG00000283059 ENSG00000076003 PMC5474494__F2 Phagocytosis mediated by receptors ENSG00000070831 ENSG00000087842 PMC5301133__F4 Protein interactome involved in neuroendocrine neoplasm proliferation.Proliferative signaling includes a tightly regulated signaling interactome (including RAS/RAF, MAPK, and PI3K/Akt) ENSG00000157764 ENSG00000130522 ENSG00000198793 ENSG00000164327 ENSG00000169032 ENSG00000121879 ENSG00000173327 ENSG00000068028 ENSG00000117020 ENSG00000166971 ENSG00000102316 ENSG00000146648 ENSG00000126458 ENSG00000196712 ENSG00000133818 ENSG00000198625 PMC2867937__F12 Segment-Specific Neuronal Subtype Specification by the Integration of Anteroposterior and Temporal Cues ENSG00000149418 PMC5301133__F2 Mechanistic basis of secretory regulation in a neuroendocrine cell ENSG00000078549 ENSG00000184845 ENSG00000149295 PMC11703838__F5 Crosstalk between TCSCs and immune cells ENSG00000154342 ENSG00000197046 ENSG00000108691 ENSG00000275718 ENSG00000198053 ENSG00000184371 ENSG00000168610 ENSG00000125084 PMC7268289__F7 Pathway bar plot explanation and pathway map explanation ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000087842 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000164305 ENSG00000164342 ENSG00000143387 PMC8580862__F9 Immune-Related Molecular Profiling of Thymoma With Myasthenia Gravis ENSG00000145604 ENSG00000007944 ENSG00000168530 ENSG00000108055 ENSG00000179091 ENSG00000132646 ENSG00000123374 ENSG00000205250 ENSG00000277273 ENSG00000117399 ENSG00000093009 PMC6025837__F6 Thyroid hormone signaling pathway ENSG00000132906 ENSG00000002330 ENSG00000198793 ENSG00000168036 PMC8870356__F1 Integrins in Modulating Smooth Muscle Cell Plasticity and Vascular Remodeling: From Expression to Therapeutic Implications ENSG00000291971 ENSG00000168036 ENSG00000146648 PMC5664393__F7 B-cell activating factor (BAFF)-BCR crosstalk in chronic lymphocytic leukemia (CLL) cells ENSG00000104856 ENSG00000186716 ENSG00000127191 ENSG00000168610 ENSG00000010671 PMC6775706__F1 Cyclin D-CDK4/6-INK4-Rb pathway in breast cancer ENSG00000094804 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000145386 PMC6775706__F2 Signaling pathways associated with tumorigenesis and combined treatments that alleviate drug resistance ENSG00000135446 ENSG00000169047 ENSG00000198793 ENSG00000123374 ENSG00000105810 ENSG00000146648 PMC6437095__F2 Interaction between miRNAs and TGFB pathway in GC ENSG00000145321 PMC6437095__F3 Interaction between miRNAs and FSH pathway in GC ENSG00000117020 ENSG00000138039 ENSG00000198793 PMC6437095__F4 Interaction between miRNAs and apoptosis pathway in GC ENSG00000002330 ENSG00000102871 ENSG00000095015 ENSG00000145321 ENSG00000168040 ENSG00000096717 ENSG00000127191 ENSG00000026103 PMC11931041__F2 Diagram of the PI3K/AKT/mTOR (PAM) signaling pathway ENSG00000005882 ENSG00000131507 ENSG00000155792 ENSG00000164327 ENSG00000167965 ENSG00000079999 PMC4645220__F13 Formononetin promotes angiogenesis through the estrogen receptor alpha-enhanced ROCK pathway ENSG00000087245 ENSG00000106683 ENSG00000100985 ENSG00000182541 PMC8859176__F10 Folic Acid Attenuates Glial Activation in Neonatal Mice and Improves Adult Mood Disorders Through Epigenetic Regulation ENSG00000066135 PMC5633884__F7 Elevated expression of Par3 promotes PCa metastasis via Hippo pathway inactivation ENSG00000122691 ENSG00000139926 PMC12252150__F2 Molecular mechanism of ERF3, SR4, DRM6-1, CHL1, NRL1, PM1, DMP2 and their role in resistance to P ENSG00000133789 ENSG00000285493 PMC9414081__F10 Research progress on extraction technology and biomedical function of natural sugar substitutes ENSG00000130164 ENSG00000113161 ENSG00000070985 PMC9414081__F11 Research progress on extraction technology and biomedical function of natural sugar substitutes ENSG00000169710 PMC11555290__F2 Decoding tumor-fibrosis interplay: mechanisms, impact on progression, and innovative therapeutic strategies ENSG00000137033 ENSG00000109321 ENSG00000146648 PMC12025727__F5 Signaling pathways activated by AEG-1 in HCC ENSG00000138795 ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000175029 ENSG00000168610 ENSG00000146648 PMC11555290__F1 (By Figdraw, ID: RASTR41933) Mechanism of fibrosis promotion by malignant tumors: Tumor cells secrete pro-fibrotic factor TGFB and activate CAFs through the TGFB/Smad signaling pathway PMC12025727__F3 Mechanisms by which AEG-1 induces MASH ENSG00000169710 ENSG00000127191 PMC8433920__F5 Phytochemicals from Polyalthia Species: Potential and Implication on Anti-Oxidant, Anti-Inflammatory, Anti-Cancer, and Chemoprevention Activities ENSG00000087245 ENSG00000002330 ENSG00000070831 ENSG00000291971 ENSG00000198793 ENSG00000168036 ENSG00000184481 ENSG00000135446 ENSG00000132646 ENSG00000123374 ENSG00000105810 ENSG00000100985 ENSG00000178691 ENSG00000146648 PMC5201051__F7 Schematic depiction of aspects of adult olfactory GBC regulation ENSG00000168283 ENSG00000114315 ENSG00000139352 ENSG00000254550 PMC4926504__F1 Signaling mechanisms of epidermal growth factor receptor (EGFR) transactivation in renal fibrosis ENSG00000291971 ENSG00000146648 PMC5742019__F1 Metabolic Strategies of Melanoma Cells: Mechanisms, Interactions with the Tumor Microenvironment, and Therapeutic Implications ENSG00000284320 ENSG00000131473 ENSG00000157764 ENSG00000100714 ENSG00000092621 ENSG00000198793 ENSG00000136997 ENSG00000169710 ENSG00000115419 ENSG00000159399 PMC7945361__F6 Proposed relationships of amphotericin biosynthesis with relevant metabolic pathways in S ENSG00000112977 ENSG00000122966 ENSG00000172005 PMC6063915__F2 PPAR Signaling Pathway and the Terpenoid Backbone Biosynthesis Pathway ENSG00000110921 ENSG00000112972 ENSG00000167910 ENSG00000113161 ENSG00000166851 ENSG00000167508 ENSG00000052802 ENSG00000157184 ENSG00000160752 ENSG00000067064 ENSG00000117054 ENSG00000132196 ENSG00000001630 ENSG00000116133 ENSG00000152904 ENSG00000149809 ENSG00000161533 ENSG00000104549 ENSG00000075239 ENSG00000113790 PMC6063915__F3 LSEC and KC signaling pathways in 3DHLK systems ENSG00000033327 ENSG00000167910 ENSG00000113161 ENSG00000120437 ENSG00000117054 ENSG00000130164 ENSG00000116133 ENSG00000161533 ENSG00000180432 ENSG00000197142 ENSG00000291905 ENSG00000164398 ENSG00000122971 ENSG00000075239 ENSG00000113790 ENSG00000169174 ENSG00000123983 ENSG00000135929 PMC3423502__F6 Crosstalk between Fgf and Wnt signaling in the zebrafish tailbud ENSG00000149922 PMC1679905__F6 Signalling routes emanating from the epidermal growth factor receptor (EGFR) ENSG00000169291 ENSG00000138798 ENSG00000146648 PMC3589096__F2 SREBP activation and input from mTORC1 signalling ENSG00000198911 PMC3897773__F7 Regulation of Amyloid Precursor Protein Processing by Serotonin Signaling ENSG00000142192 ENSG00000291971 ENSG00000151151 PMC209288__F1 The biosynthetic pathway for the fibrillar collagens expressed in skin, identifying steps that are affected in different forms of EDS ENSG00000291748 ENSG00000108821 PMC3661399__F7 Selected AMPK and IGF-IR signalling pathways relevant to this study in normal (A) and hyperglycaemic (B) conditions ENSG00000169047 ENSG00000198793 PMC9556450__F2 Drug transport across the blood-testis barrier ENSG00000070831 ENSG00000198734 PMC3295081__F1 Age-related Dysregulation of Inflammation and Innate Immunity: Lessons Learned from Rodent Models ENSG00000172936 ENSG00000136869 PMC9505027__F1 MicroRNA: A Linking between Astrocyte Dysfunction, Mild Cognitive Impairment, and Neurodegenerative Diseases ENSG00000115415 ENSG00000109320 ENSG00000005882 ENSG00000198793 ENSG00000185591 ENSG00000205250 ENSG00000105810 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000198625 PMC8669491__F3 Altered protein secretion in Batten disease ENSG00000166340 ENSG00000261832 ENSG00000064601 PMC8035226__F2 Metabolism of multiple substrates supports acetyl-CoA production in the fat cell ENSG00000131473 ENSG00000169710 PMC10778207__F4 Src intracellular signaling pathway and various cellular processes controlled by each pathway ENSG00000291971 ENSG00000198793 ENSG00000168610 PMC5552707__F8 Network analysis of the gene pathways* catalogued in the Panther database, which - directly or indirectly - are connected with AD upon activation with Hp(2-20) ENSG00000140992 ENSG00000065675 ENSG00000281324 ENSG00000137601 ENSG00000044115 ENSG00000291971 ENSG00000241553 ENSG00000171049 ENSG00000170677 ENSG00000095015 ENSG00000169884 ENSG00000168036 ENSG00000138071 ENSG00000168615 ENSG00000155903 ENSG00000100485 ENSG00000120256 ENSG00000065243 ENSG00000142166 ENSG00000171051 ENSG00000111229 ENSG00000129219 ENSG00000175634 ENSG00000117148 ENSG00000143801 ENSG00000168214 ENSG00000163251 ENSG00000163558 ENSG00000183943 ENSG00000263528 ENSG00000197943 ENSG00000187678 ENSG00000142192 ENSG00000157764 ENSG00000148400 ENSG00000065361 ENSG00000109320 ENSG00000033800 ENSG00000173039 ENSG00000065559 ENSG00000162924 ENSG00000177606 ENSG00000186654 PMC10886920__F1 Signaling Pathways of AXL Receptor Tyrosine Kinase Contribute to the Pathogenetic Mechanisms of Glioblastoma ENSG00000167601 ENSG00000115415 ENSG00000198793 ENSG00000100985 ENSG00000168610 PMC3447932__F10 Vsx2 Controls Eye Organogenesis and Retinal Progenitor Identity Via Homeodomain and Non-Homeodomain Residues Required for High Affinity DNA Binding ENSG00000119614 ENSG00000115507 PMC3438665__F1 p53-dependent and -independent therapeutic strategies for cancer cells ENSG00000198793 ENSG00000274089 PMC10379333__F3 Pulmonary Sarcoidosis: Experimental Models and Perspectives of Molecular Diagnostics Using Quantum Dots ENSG00000108691 ENSG00000198793 PMC7593515__F2 YAP/TAZ by core components of Hippo signaling pathway ENSG00000167601 ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC6620386__F8 microRNA-613 exerts anti-angiogenic effect on nasopharyngeal carcinoma cells through inactivating the AKT signaling pathway by down-regulating FN1 ENSG00000198793 PMC8683078__F2 Biofactoid data is connected to information sources and establishes a bridge between related pathways ENSG00000079387 ENSG00000142082 ENSG00000081189 ENSG00000124762 ENSG00000177606 ENSG00000171759 ENSG00000174197 ENSG00000124523 ENSG00000116030 ENSG00000188612 ENSG00000140464 ENSG00000184900 ENSG00000105662 PMC3513366__F1 Progastrin Peptides Increase the Risk of Developing Colonic Tumors: Impact on Colonic Stem Cells ENSG00000133083 ENSG00000124102 ENSG00000157764 ENSG00000042832 ENSG00000134982 ENSG00000026508 ENSG00000168036 ENSG00000168610 ENSG00000135097 PMC7593515__F3 Hippo signaling pathway and potential inhibitors of YAP/TEAD ENSG00000141867 ENSG00000126016 ENSG00000169047 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC8124199__F2 JAK/STAT Molecular Pathway in Vascular Remodeling Associated with Pulmonary Hypertension ENSG00000105397 ENSG00000115415 ENSG00000168610 PMC8124199__F3 JAK/STAT Molecular Pathway in Vascular Remodeling Associated with Pulmonary Hypertension ENSG00000100985 PMC5944149__F2 The overexpression of tRNAs regulated the progression of cancer acting on different ways: Ras, c-myc and TERT promoted the transcription of tRNA genes by binding to pol III ENSG00000065361 ENSG00000164362 PMC6815315__F3 GSK3 regulates cell death, renewal, and differentiation ENSG00000134982 ENSG00000169047 ENSG00000168036 PMC7667862__F9 Model for OTUD7B deubiquitination of TRAF3 and inhibition of NIK to suppress LCL161-induced lung cancer cell invasion and migration ENSG00000104856 ENSG00000264522 ENSG00000131323 PMC9291723__F1 Ferroptosis in Acute Kidney Injury ENSG00000163930 ENSG00000161905 ENSG00000197635 ENSG00000181019 ENSG00000167468 ENSG00000167996 ENSG00000111684 PMC6815315__F1 GSK3b and growth regulation ENSG00000134982 ENSG00000169047 ENSG00000198793 PMC8514750__F4 GTPase-Dependent Mitochondrial Dynamins in Heart Diseases ENSG00000096717 ENSG00000142082 ENSG00000188612 ENSG00000184900 PMC8514750__F5 GTPase-Dependent Mitochondrial Dynamins in Heart Diseases ENSG00000162600 ENSG00000142082 PMC8226626__F1 JAK/STAT in Interstitial Lung Diseases; Molecular and Cellular Mechanisms ENSG00000105397 ENSG00000115415 ENSG00000204671 ENSG00000138798 ENSG00000113520 ENSG00000105639 ENSG00000168610 PMC3414439__F4 Combinatorial Drug Discovery Using Transcriptional Response Modules ENSG00000182533 ENSG00000291971 ENSG00000131747 ENSG00000127955 ENSG00000164305 PMC3677821__F2 Schematic showing some major pathways implicated in cancer progression using Drosophila studies ENSG00000105664 ENSG00000291971 ENSG00000136997 PMC8924142__F1 Type I interferon-mediated tumor immunity and its role in immunotherapy ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000198793 ENSG00000142166 PMC8924142__F2 Type I interferon-mediated tumor immunity and its role in immunotherapy ENSG00000124256 ENSG00000173638 ENSG00000197992 ENSG00000110057 ENSG00000127666 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000189403 ENSG00000136869 ENSG00000172936 ENSG00000164342 PMC1193534__F1 Comparative Genomics of Natural Killer Cell Receptor Gene Clusters ENSG00000213658 ENSG00000291971 ENSG00000284100 ENSG00000043462 ENSG00000173402 ENSG00000141968 ENSG00000160691 PMC4691064__F5A Transcriptomic Response to Nitric Oxide Treatment in Larix olgensis Henry ENSG00000111816 ENSG00000083845 PMC7316979__F3 Interaction networks from significantly upregulated serum cytokines from cancer survivors ENSG00000107562 ENSG00000197635 ENSG00000138798 ENSG00000132693 ENSG00000197461 ENSG00000115602 ENSG00000138207 ENSG00000261371 ENSG00000133048 ENSG00000011422 ENSG00000118785 ENSG00000106327 ENSG00000160180 ENSG00000102245 ENSG00000102970 ENSG00000145321 ENSG00000100985 ENSG00000162692 ENSG00000130513 PMC9460763__F5 Impaired autophagy with augmented apoptosis in a Th1/Th2-imbalanced placental micromilieu is associated with spontaneous preterm birth ENSG00000144848 ENSG00000057663 PMC3625555__F3 Neuroactive ligand-receptor interaction and calcium signaling pathway ENSG00000156026 ENSG00000186716 ENSG00000168229 ENSG00000170893 ENSG00000198670 ENSG00000092820 PMC8666534__F5 Review on the Role of AFAP1-AS1 in the Pathoetiology of Cancer ENSG00000140285 ENSG00000127528 PMC6932950__F1 An overview of current and emerging agents for TNBC therapy ENSG00000228716 ENSG00000012048 ENSG00000135446 ENSG00000198793 ENSG00000164690 ENSG00000128602 PMC7593950__F5 Simplified scheme of putative role, function, and involvement of VEGF, PlGF, and IGFBP-3 in signaling pathways described in angiogenesis and tumor growth ENSG00000070831 ENSG00000198793 ENSG00000124181 PMC9261367__F6 T-Cell Aging-Associated Phenotypes in Autoimmune Disease ENSG00000103769 ENSG00000144566 PMC7017752__F3 Emerging therapeutic targets for neurofibromatosis type 1 (NF1) ENSG00000157404 ENSG00000184371 ENSG00000168036 ENSG00000196712 PMC10136628__F1 Metabolic pathway of tetrahydrobiopterin (BH4) ENSG00000228716 ENSG00000171759 PMC7280434__F1 Current strategies to overcome multidrug resistance ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC3834778__F4 Shear stress reveals the mechanisms by which OA induces PICs and MMPs in human chondrocytes ENSG00000136869 ENSG00000173846 ENSG00000166851 ENSG00000026103 PMC3834778__F5 Networks of shear stress-induced OA progression ENSG00000125538 PMC7017752__F2 Emerging therapeutic targets for neurofibromatosis type 1 (NF1) ENSG00000198793 ENSG00000196712 PMC2712453__F5 Erb-associated signaling pathways ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000173599 PMC8699595__F2 Abscission Checkpoint: A Guardian of Chromosomal Stability ENSG00000149311 ENSG00000164695 ENSG00000138180 ENSG00000101421 ENSG00000149503 PMC2712453__F6 TLR-mediated innate immune signaling pathway ENSG00000174123 ENSG00000174125 ENSG00000171855 ENSG00000115008 ENSG00000110324 ENSG00000168040 ENSG00000142166 ENSG00000239732 ENSG00000111537 ENSG00000224320 ENSG00000187554 ENSG00000136869 ENSG00000172936 ENSG00000115594 ENSG00000026103 ENSG00000164342 PMC6770077__F1 Pathway shows the influence of adipocytes on cancer ENSG00000136868 ENSG00000171105 ENSG00000169047 ENSG00000198793 ENSG00000159346 ENSG00000285070 PMC2712453__F7 Signaling pathway inferred from a gene regulatory network ENSG00000070831 ENSG00000197601 PMC8178558__F1 Innate type 1 immune response, but not IL-17 cells control tuberculosis infection ENSG00000183735 ENSG00000164430 PMC2712453__F2 G1-phase signaling pathways inferred with different heuristics ENSG00000175854 ENSG00000136425 ENSG00000117399 PMC2712453__F3 S-phase signaling pathways inferred with different heuristics ENSG00000094804 ENSG00000129596 ENSG00000197601 ENSG00000093009 PMC10518420__F3 An emerging research: the role of hepatocellular carcinoma-derived exosomal circRNAs in the immune microenvironment ENSG00000111537 PMC8253500__F4 Comprehensive Analysis of lncRNA and miRNA Regulatory Network Reveals Potential Prognostic Non-coding RNA Involved in Breast Cancer Progression ENSG00000292149 ENSG00000288174 ENSG00000169031 PMC3234318__F1 OB inhibition by MM cells ENSG00000019991 ENSG00000197272 ENSG00000164399 ENSG00000104432 PMC5531462__F6 Prediction of novel target genes and pathways involved in irinotecan-resistant colorectal cancer ENSG00000102678 PMC3882682__F8 Canonical pathways ENSG00000177455 ENSG00000110651 ENSG00000136869 ENSG00000134061 ENSG00000117322 ENSG00000010671 PMC5531462__F4 Prediction of novel target genes and pathways involved in irinotecan-resistant colorectal cancer ENSG00000105499 ENSG00000102678 PMC2706303__F2 Bioelectric mechanisms in regeneration: unique aspects and future perspectives ENSG00000100146 PMC7757044__F1 Roles of related miRNAs during the phases of autophagy ENSG00000177169 ENSG00000110497 ENSG00000152348 ENSG00000123395 ENSG00000198382 ENSG00000083290 ENSG00000198793 ENSG00000118640 ENSG00000136874 ENSG00000057663 ENSG00000292366 ENSG00000005893 ENSG00000144848 ENSG00000096717 ENSG00000145782 PMC4189469__F1 Schematic illustrating mechanism for expression and function of regulatory genes for development of the oviduct and for development of epithelial-derived ovarian cancer ENSG00000206072 ENSG00000057149 ENSG00000118785 ENSG00000175899 PMC3033586__F2 Wnt pathway and its regulation of Beta-catenin in stem cells and cancer ENSG00000134982 ENSG00000026508 ENSG00000168036 PMC7702481__F5 Dangers of déjà vu: memory B cells as the cells of origin of ABC-DLBCLs ENSG00000116815 ENSG00000173599 ENSG00000145321 ENSG00000198125 PMC9606746__F1 Terpenoid natural products exert neuroprotection via the PI3K/Akt pathway ENSG00000198793 ENSG00000168036 PMC6736714__F8 Gli phosphorylation code ENSG00000128602 PMC10295080__F1 Nrf2 signalling pathway ENSG00000023909 ENSG00000079999 PMC8670931__F5 Novel Genes Potentially Involved in Fibroblasts of Diabetic Wound ENSG00000162889 ENSG00000115884 ENSG00000170370 ENSG00000140937 ENSG00000126803 ENSG00000197971 ENSG00000175832 ENSG00000064655 PMC10244678__F9 Bacteroides dorei BDX-01 alleviates DSS-induced experimental colitis in mice by regulating intestinal bile salt hydrolase activity and the FXR-NLRP3 signaling pathway ENSG00000162711 PMC4118478__F1 p53 at the crossroads of MPN treatment ENSG00000105397 ENSG00000115415 ENSG00000198793 PMC7691375__F1 Comparison of mouse and human pro-resolving macrophages ENSG00000239732 ENSG00000125538 ENSG00000136869 ENSG00000118520 PMC8928416__F4 NOD1 and NOD2 in inflammatory and infectious diseases ENSG00000088888 ENSG00000167207 ENSG00000152137 ENSG00000131323 ENSG00000145782 ENSG00000127191 ENSG00000106100 ENSG00000276561 ENSG00000057663 PMC11908617__F4 Effect of ZNFs on CRC metastasis‐related pathways [46, 47, 51, 52, 55] ENSG00000126746 ENSG00000168036 ENSG00000198185 ENSG00000162664 ENSG00000197714 PMC4072689__F5 Hijacking of Host Cellular Functions by an Intracellular Parasite, the Microsporidian Anncaliia algerae ENSG00000213928 ENSG00000157601 ENSG00000185745 ENSG00000050405 ENSG00000276561 ENSG00000169567 ENSG00000089159 PMC5299128__F6 Atoh1 as a Coordinator of Sensory Hair Cell Development and Regeneration in the Cochlea ENSG00000172238 PMC8838402__F10 Probable Mechanisms of Doxorubicin Antitumor Activity Enhancement by Ginsenoside Rh2 ENSG00000182718 ENSG00000086991 ENSG00000122194 PMC4127876__F1 Diagram depicting hypothetical mechanisms by which the polycystins directly affect gene transcription and regulate the cell cycle ENSG00000115415 ENSG00000168036 ENSG00000123374 PMC6681802__F1 Pharmacokinetic and pharmacodynamics pathways for mycophenolate mofetil ENSG00000172831 ENSG00000106348 ENSG00000138115 ENSG00000178035 ENSG00000171234 ENSG00000023839 PMC8083963__F1 Toward Understanding the Molecular Role of SNX27/Retromer in Human Health and Disease ENSG00000116729 ENSG00000112335 ENSG00000143376 ENSG00000146648 PMC8083963__F2 Toward Understanding the Molecular Role of SNX27/Retromer in Human Health and Disease ENSG00000180210 ENSG00000117525 ENSG00000111237 ENSG00000069329 PMC6987486__F2 Mechanisms of how Sfrps modulate cellular apoptosis, angiogenesis, differentiation, inflammatory process, and cardiac remodeling ENSG00000154342 ENSG00000019991 ENSG00000138795 ENSG00000168487 ENSG00000168036 ENSG00000106483 ENSG00000026103 PMC4435778__F5 Meiotic recombination ENSG00000051180 ENSG00000100206 ENSG00000054796 PMC12005559__F2 Cholesterol metabolism and transport pathways ENSG00000130164 PMC12005559__F3 Anchor model of female steroidogenesis, describing the estradiol synthesis pathway, its regulation, and perturbation by dioxin ENSG00000108786 ENSG00000203857 PMC3463457__F1 Normalization of sphingomyelin levels by 2-hydroxyoleic acid induces autophagic cell death of SF767 cancer cells ENSG00000150907 ENSG00000198793 ENSG00000105810 ENSG00000124762 PMC3674226__F3 Where No Synapses Go: Gatekeepers of Circuit Remodeling and Synaptic Strength ENSG00000198793 PMC5233484__F1 The canonical and non-canonical autophagy pathways ENSG00000177169 ENSG00000057663 PMC4557770__F1 B cell receptor (BCR) signaling pathway and molecular interactions in the CLL microenvironment ENSG00000107562 ENSG00000186716 ENSG00000198793 ENSG00000126353 ENSG00000162692 ENSG00000277943 ENSG00000010671 ENSG00000121966 PMC8549879__F1 Hepatic LC3 II/I Ratio Is Not Modulated in Exercised Mice ENSG00000126775 ENSG00000144848 ENSG00000171791 ENSG00000145782 ENSG00000057663 PMC9189063__F3 IFNB basal expression through TLR4/TBK/IRF3 pathway ENSG00000136869 PMC10949727__F3 FOXO3a regulating EMT and drug resistance in breast cancer ENSG00000145604 ENSG00000141867 ENSG00000105810 ENSG00000077463 PMC8185863__F2 Epithelial-mesenchymal transition-related circular RNAs in lung carcinoma ENSG00000134982 ENSG00000168036 ENSG00000123908 ENSG00000276043 PMC6158482__F1 Neutralization of the interleukin-12/interleukin-23 pathways associated with T-cell activation and differentiation ENSG00000162594 ENSG00000096996 PMC5358800__F1 Myelodysplastic syndromes: updates and nuances ENSG00000198901 ENSG00000101972 ENSG00000169249 ENSG00000115524 ENSG00000159216 ENSG00000171456 ENSG00000183337 PMC11706994__F8 LCWE-induced ALI ENSG00000162711 ENSG00000172936 ENSG00000136869 PMC11615488__F5 Map of phospho-proteins in cellular signaling pathways that regulate YPP expression in mosquito fat body ENSG00000198382 ENSG00000100330 ENSG00000224470 ENSG00000198793 ENSG00000144848 ENSG00000164327 ENSG00000171791 ENSG00000133961 ENSG00000145782 PMC4214761__F5 Expression Analysis of All Protease Genes Reveals Cathepsin K to Be Overexpressed in Glioblastoma ENSG00000124102 ENSG00000019582 ENSG00000072274 ENSG00000143387 PMC7700615__F2 Signaling via TGFB receptors initiated at different intracellular locations and sites of inhibition by RAC1B ENSG00000291971 ENSG00000198742 PMC4158461__F7 The underlying mechanism of CFE on the TLR4 signaling pathway ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC9420733__F6 Signaling pathways in obesity: mechanisms and therapeutic interventions ENSG00000185231 ENSG00000198576 ENSG00000115138 ENSG00000124089 ENSG00000166603 ENSG00000131096 PMC3142564__F3A Targeting the phosphoinositide 3-kinase (PI3K) pathway in cancer ENSG00000198793 ENSG00000146648 PMC9420733__F2 Signaling pathways in obesity: mechanisms and therapeutic interventions ENSG00000169047 ENSG00000115138 ENSG00000126838 PMC9420733__F3 Signaling pathways in obesity: mechanisms and therapeutic interventions ENSG00000187871 ENSG00000115138 ENSG00000184344 ENSG00000130513 PMC9420733__F4 Signaling pathways in obesity: mechanisms and therapeutic interventions ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000185269 ENSG00000168610 ENSG00000171604 ENSG00000130703 ENSG00000087274 PMC8145522__F2 Contributions of Ubiquitin and Ubiquitination to Flaviviral Antagonism of Type I IFN ENSG00000135655 ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000121060 ENSG00000276561 PMC9420733__F5 Signaling pathways in obesity: mechanisms and therapeutic interventions ENSG00000115138 ENSG00000169710 PMC10949727__F2 FOXO3a regulating apoptosis and cell cycle in breast cancer ENSG00000132906 ENSG00000164305 ENSG00000026103 PMC8996682__F6 Blood–brain barrier and the neurovascular unit in subarachnoid hemorrhage: molecular events and potential treatments ENSG00000177575 ENSG00000162711 ENSG00000168329 ENSG00000168036 ENSG00000172936 ENSG00000136869 ENSG00000162692 ENSG00000112486 PMC6260991__F7 Schematic representation for hypothetical M2 macrophage-induced myofibroblast differentiation of LR-MSCs ENSG00000154764 ENSG00000168036 ENSG00000157240 PMC8469180__F3 Nicotinamide Adenine Dinucleotide Phosphate Oxidases in Glucose Homeostasis and Diabetes-Related Endothelial Cell Dysfunction ENSG00000169047 PMC3813872__F7 Models of Eph signaling in amphid axon guidance ENSG00000118515 PMC5629631__F23 Multiple modes of AOAA’s action in cancer cells ENSG00000125166 PMC2872012__F4 Functional genetic network as defined by the bioPIXIE tool (Myers et al ENSG00000166477 ENSG00000137815 ENSG00000136100 ENSG00000104142 ENSG00000111237 ENSG00000163159 ENSG00000107036 ENSG00000164105 PMC7883806__F1 Wnt signaling pathway ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000100592 ENSG00000134982 ENSG00000185483 ENSG00000168036 PMC2872012__F5 Detailed representation of the interactions between the components of the gene network ENSG00000111237 ENSG00000163159 ENSG00000069329 PMC6125421__F2 Signaling pathways of the unfolded protein response ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8023019__F1 Rationale for the combined use of an ICD inducer and an IDO-1 inhibitor ENSG00000134982 ENSG00000198793 ENSG00000189403 ENSG00000106546 PMC3434988__F1 Hepatocyte growth factor (HGF)–cMET axis signaling network and ongoing targeted therapy strategies ENSG00000019991 ENSG00000109534 ENSG00000141564 ENSG00000146648 PMC7925880__F6 LREE regulates bile acid metabolism through intestinal flora ENSG00000130164 ENSG00000160867 PMC7734567__F2 Mapping the 12 pairs of genes, which are positively correlated in all 12 types of cancer, into the tryptophan metabolic pathway ENSG00000120437 ENSG00000241644 ENSG00000105607 ENSG00000113790 ENSG00000181192 ENSG00000091140 ENSG00000138356 PMC6374451__F7 Schematic overview of DNA demethylation during glioma progression ENSG00000124102 ENSG00000135446 ENSG00000121879 ENSG00000136231 PMC2998559__F1 Model Depicting major molecules and events in mast cell activation ENSG00000033327 ENSG00000213658 ENSG00000167323 ENSG00000293604 ENSG00000010671 PMC6779289__F2 PPI network generated for the proteins encoded by the eight statistical driver genes ENSG00000010671 ENSG00000095585 ENSG00000274619 ENSG00000175054 ENSG00000113456 ENSG00000116785 ENSG00000143801 ENSG00000084676 ENSG00000168214 ENSG00000128917 ENSG00000182185 ENSG00000108384 ENSG00000125686 ENSG00000132383 ENSG00000117335 ENSG00000196352 ENSG00000197943 ENSG00000196498 ENSG00000113263 ENSG00000213809 ENSG00000204520 ENSG00000169896 ENSG00000000971 ENSG00000043462 ENSG00000139618 ENSG00000197299 ENSG00000146648 ENSG00000135605 ENSG00000122008 PMC3626710__F5 Results from single pathway sets ENSG00000081181 ENSG00000109743 ENSG00000118520 ENSG00000078674 ENSG00000169299 ENSG00000013375 PMC6889286__F2 Resistance mechanisms to osimertinib in EGFR-mutated non-small cell lung cancer ENSG00000167601 ENSG00000157764 ENSG00000198793 ENSG00000047936 ENSG00000168610 ENSG00000146648 PMC6628002__F2 Schematic representation of physiological and pathological aspects (major sources of oxidative stress) in Alzheimer’s disease (AD) and their corresponding antioxidant defense approach by anthocyanin in cholinergic neurons ENSG00000142192 ENSG00000131095 ENSG00000164305 PMC7884371__F2 The NLRP3 inflammasome pathway ENSG00000278718 ENSG00000162711 ENSG00000167207 ENSG00000137275 ENSG00000125538 ENSG00000172936 ENSG00000168040 PMC7929492__F1 Canonical activation pathway for the NLRP3 inflammasome ENSG00000162711 ENSG00000125538 ENSG00000173039 ENSG00000172936 ENSG00000136869 PMC5775519__F1 Pattern recognition receptors (PRRs) for human immunodeficiency virus type 1 (HIV-1) recognition and the following pathway for triggering type I interferon (IFN-I) expression ENSG00000164430 ENSG00000163565 ENSG00000172936 ENSG00000276561 PMC8568271__F5 Interleukin-1 activation of NF-kB through Ajuba ENSG00000129474 ENSG00000083799 ENSG00000175104 PMC11125956__F11 Osteoblasts in Rheumatoid Arthritis Pathway ENSG00000152266 ENSG00000154342 ENSG00000137834 ENSG00000107404 ENSG00000156076 ENSG00000105329 ENSG00000242252 ENSG00000134982 ENSG00000164761 ENSG00000291971 ENSG00000162551 ENSG00000120693 ENSG00000171791 ENSG00000170365 ENSG00000118785 ENSG00000198742 ENSG00000155011 ENSG00000115266 ENSG00000291837 ENSG00000184371 ENSG00000108821 ENSG00000204217 PMC5775519__F2 Type I interferons (IFN-I)-initiated signaling pathway leading to interferon-stimulated gene (ISG) expression ENSG00000213928 ENSG00000115415 PMC9099669__F2 Demystifying the Neuroprotective Role of Neuropeptides in Parkinson’s Disease: A Newfangled and Eloquent Therapeutic Perspective ENSG00000158828 ENSG00000069329 ENSG00000115317 PMC11125956__F13 B Cell Receptor Signaling Pathway, KEGG ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000145321 ENSG00000153064 ENSG00000110651 ENSG00000152689 ENSG00000010671 PMC11854592__F2 The EpCAM signaling pathway in cancer progression ENSG00000138795 ENSG00000119888 ENSG00000168036 ENSG00000146648 PMC3429092__F4 TRPC5-mediated feedback of Ca2+ and NO signaling in endothelial cells and attenuation of Ca2+ entry through TRPC6 by NO in smooth muscle cells ENSG00000137672 ENSG00000072315 PMC9099669__F5 Demystifying the Neuroprotective Role of Neuropeptides in Parkinson’s Disease: A Newfangled and Eloquent Therapeutic Perspective PMC7463463__F1 Amino acid metabolic pathways altered in cancer and select inhibitors targeting these pathways ENSG00000070831 ENSG00000149269 ENSG00000183077 ENSG00000106546 PMC7463463__F2 Targetable vulnerabilities related to serine and 1C metabolism ENSG00000284320 ENSG00000228716 ENSG00000092621 ENSG00000102967 PMC7439204__F5 Anti-ARDS pathway of YQHYJD in KEGG ENSG00000169291 ENSG00000002330 ENSG00000110395 ENSG00000163235 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000136997 ENSG00000158458 ENSG00000169752 PMC10975212__F1 TGFB/SMAD signaling pathway ENSG00000170365 ENSG00000137834 PMC3462343__F7 Model depicting how chronic exposure to SAg could elicit an autoimmune disease ENSG00000134982 ENSG00000186716 ENSG00000281857 PMC2785474__F4 TLR4 and chemokine receptor cross-talk ENSG00000136869 PMC11987241__F8 M2Φ-exos-mediated TGFB1-induced phenotypic transformation in BEAS-2B cells PMC10975212__F5 Non-SMAD, non-canonical TGFB pathways ENSG00000137834 ENSG00000070831 ENSG00000198793 ENSG00000175104 ENSG00000076604 PMC2785474__F2 TLR signaling (an example in macrophages and dendritic cells) ENSG00000174125 ENSG00000150455 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000134070 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC10525362__F1 Calcium, Phosphorus and Magnesium Abnormalities Associated with COVID-19 Infection, and Beyond ENSG00000111012 ENSG00000205221 ENSG00000105516 ENSG00000135929 PMC3255783__F7 Model depicting the potential roles of Hrq1 in NER-based lesion processing ENSG00000132646 ENSG00000136936 PMC11089204__F5 Proposed metabolic pathway of psilocybin and its active metabolite psilocin PMC4591813__F5 ErbB3 in RAF-inhibited mutant BRAF melanoma cells ENSG00000065361 PMC10670187__F1 LncRNA MIR4435-2HG is involved in signaling pathways for cancer progression ENSG00000146670 ENSG00000124216 ENSG00000291754 ENSG00000170558 ENSG00000198793 ENSG00000168036 ENSG00000100985 PMC3121749__F8 Graded Nodal/Activin Signaling Titrates Conversion of Quantitative Phospho-Smad2 Levels into Qualitative Embryonic Stem Cell Fate Decisions ENSG00000137834 ENSG00000157933 ENSG00000143768 ENSG00000243709 ENSG00000147869 ENSG00000241186 ENSG00000177606 ENSG00000156574 PMC4863644__F2 Glucose stimulated insulin secretion (GSIS) and suggested stimulus/secretion coupling factors ENSG00000159224 ENSG00000173599 ENSG00000079432 PMC7128029__F1 BA synthesis and transport pathway ENSG00000167910 ENSG00000173599 ENSG00000081923 PMC2943748__F6 SENP1 participates in the dynamic regulation of Elk-1 SUMOylation ENSG00000079387 ENSG00000196591 PMC10217757__F1 Specific Features of Focal Cortical Dysplasia in Tuberous Sclerosis Complex ENSG00000198793 ENSG00000145979 ENSG00000155792 ENSG00000204673 ENSG00000141564 PMC2759942__F5 Analyses of regenerative wave patterns in adult hair follicle populations reveal macro-environmental regulation of stem cell activity PMC7466447__F1 Immunoregulatory functions of TEC in the TME ENSG00000169245 ENSG00000164430 ENSG00000111537 ENSG00000172889 ENSG00000135605 PMC7281325__F3 Multi-omic study identified up- and downregulated candidates in acquired trastuzumab-resistant BT-474.r2T cells compared to parental sensitive BT-474 cells ENSG00000167644 ENSG00000169248 ENSG00000135547 ENSG00000136152 ENSG00000002330 ENSG00000070814 ENSG00000128951 ENSG00000099812 ENSG00000161405 ENSG00000019102 ENSG00000178209 ENSG00000166387 ENSG00000167653 ENSG00000073111 ENSG00000125999 ENSG00000149929 ENSG00000282825 ENSG00000089159 ENSG00000160007 ENSG00000291875 ENSG00000125686 ENSG00000102104 ENSG00000078674 ENSG00000074219 ENSG00000169245 ENSG00000113758 ENSG00000282941 ENSG00000047849 ENSG00000001461 ENSG00000170477 ENSG00000134531 PMC5259880__F3 The molecular mechanisms dysregulated in PD and thought to lead to DAergic neuronal cell death ENSG00000184381 ENSG00000100225 ENSG00000115317 PMC9221436__F4 Targeting Breast Cancer-Derived Stem Cells by Dietary Phytochemicals: A Strategy for Cancer Prevention and Treatment ENSG00000168283 ENSG00000122691 ENSG00000198793 ENSG00000026508 ENSG00000168036 ENSG00000136826 PMC6040288__F9 Network pathway: pathway enrichment analysis was performed ENSG00000142192 ENSG00000182511 ENSG00000115310 ENSG00000168040 PMC10945329__F9 ADSCs-Exo pathway reduces pyroptosis and improves tissue regeneration in the liver, which has been injured by ischemia-reperfusion and partial resection ENSG00000278718 ENSG00000162711 ENSG00000168036 ENSG00000136869 PMC3047798__F3 Wnt signaling components regulate ubiquitylation ENSG00000134982 ENSG00000168036 ENSG00000196470 PMC3187166__F1 Selected part of the central metabolism in C ENSG00000074800 ENSG00000150787 ENSG00000062485 PMC5491788__F9 Intestinal FXR and TGR5 cross-talk in the regulation of GLP-1 secretion, hepatic bile aid synthesis, glucose and lipid metabolism, and insulin and glucose sensitivity ENSG00000160867 ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC5615985__F6 Role of the LGM2605 in preventing asbestos-induced inflammation, oxidative/nitrosative cell damage, cell injury, and cell death proposed mechanism of asbestos-induced inflammation and oxidative/nitrosative stress and the protective effect of LGM2605 ENSG00000162711 ENSG00000189403 PMC3047798__F1 Ubiquitin-mediated regulation of the core Wnt pathway components APC, Axin and Beta-catenin ENSG00000135655 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000196470 ENSG00000173273 PMC3142070__F4 Cause and metabolic consequences of fatty liver ENSG00000170522 ENSG00000129214 ENSG00000062282 PMC4718179__F4 Activation of EGC and induction of a reactive EGC phenotype ENSG00000125398 ENSG00000005513 ENSG00000131095 ENSG00000100146 PMC8303222__F2 Importance of Being PI3K in the RAS Signaling Network ENSG00000168036 ENSG00000010671 PMC6247401__F6 Proposed role of macrophage LRP1 depicted in diet-induced inflammatory conditions ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000120057 ENSG00000168036 PMC4897783__F8 Glucose induced activation of canonical Wnt signaling pathway in hepatocellular carcinoma is regulated by DKK4 ENSG00000162337 ENSG00000104371 ENSG00000168036 PMC2692402__F1 Glycerol phosphate pathway for de novo triacylglycerol (TAG) and glycerophospholipid synthesis ENSG00000173599 ENSG00000158669 ENSG00000285482 ENSG00000198670 ENSG00000026652 ENSG00000160216 ENSG00000186281 ENSG00000062282 PMC5665759__F3 Androgen‐regulated lncRNAs, SOCS2‐AS1 and POTEF‐AS1 promote prostate cancer growth ENSG00000120833 ENSG00000196604 ENSG00000164342 PMC4320821__F4 Network graph showing interactions between ID2 and ID3 and their MIC-inferred ‘target’ genes regulating cell death ENSG00000100811 ENSG00000027075 ENSG00000140678 ENSG00000005339 ENSG00000197081 ENSG00000108861 ENSG00000102871 ENSG00000100450 ENSG00000173039 ENSG00000196470 ENSG00000171791 ENSG00000073756 ENSG00000136826 ENSG00000137801 ENSG00000143507 ENSG00000177606 ENSG00000136997 ENSG00000185591 ENSG00000283060 ENSG00000188612 ENSG00000184900 ENSG00000095794 ENSG00000158050 PMC3088996__F3 Regulatory role of ATM in cellular responses to DNA DSB repair ENSG00000149311 ENSG00000012048 ENSG00000144554 ENSG00000123374 PMC4184842__F6 Gene Expression Response of Chronic Lymphocytic Leukemia Cells to IL-4 Is Specific, Depends on ZAP-70 Status and Is Differentially Affected by an NFKB Inhibitor ENSG00000291603 ENSG00000100906 ENSG00000169047 ENSG00000105639 PMC8927800__F3 Type 2 Diabetes Complicated With Heart Failure: Research on Therapeutic Mechanism and Potential Drug Development Based on Insulin Signaling Pathway ENSG00000132906 ENSG00000002330 ENSG00000153283 ENSG00000198793 PMC5795460__F1 Only the classical role of the Fanconi anemia (FA) pathway in the repair of interstrand cross-links (ICLs) is depicted, which involves highly coordinated protein–DNA and protein–protein interactions in the nucleus ENSG00000149311 ENSG00000175054 ENSG00000144554 ENSG00000181544 ENSG00000187790 ENSG00000115392 ENSG00000187741 ENSG00000112039 ENSG00000158169 PMC5770079__F6 Apoptosis signaling pathway ENSG00000132906 ENSG00000128272 ENSG00000102871 ENSG00000138794 ENSG00000120868 ENSG00000171791 ENSG00000168040 ENSG00000127191 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC8641876__F1 Schematic depiction of the regulatory network of YAP/TAZ ENSG00000150457 ENSG00000096717 ENSG00000131023 PMC8927800__F1 Type 2 Diabetes Complicated With Heart Failure: Research on Therapeutic Mechanism and Potential Drug Development Based on Insulin Signaling Pathway ENSG00000169047 ENSG00000198793 PMC6635453__F5 Proposed pathway for RQ biosynthesis in C ENSG00000132423 ENSG00000119723 ENSG00000110871 ENSG00000173085 PMC6966492__F1 Cell death pathways triggered by the temozolomide-induced DNA lesion O6-methylguanine ENSG00000149311 ENSG00000175054 ENSG00000064393 ENSG00000170430 ENSG00000196470 ENSG00000026103 PMC8888891__F2 Targeting the GLP-1/GLP-1R axis to treat osteoarthritis: A new opportunity? ENSG00000125398 ENSG00000198742 ENSG00000198793 ENSG00000177606 ENSG00000168036 ENSG00000159346 ENSG00000100219 ENSG00000175104 ENSG00000127191 ENSG00000131196 PMC7294112__F7 Schematic to represent the proposed molecular events in DHL‐induced apoptosis in laryngeal carcinoma cells ENSG00000002330 PMC2919149__F7 Targeting HIF activation pathway for cancer therapy ENSG00000134086 ENSG00000198793 ENSG00000156467 PMC10028837__F1 The oxidative phase of the pentose phosphate pathway including 6-phosphogluconolactonase (Pgl), that converts 6-P-gluconololactone to gluconate-6-P ENSG00000226275 ENSG00000084110 ENSG00000185129 ENSG00000146676 PMC7052781__F2 Metabolic coordination of macrophage activation ENSG00000135218 ENSG00000111537 ENSG00000136869 PMC5482192__F5 Ten differentially expressed genes between human bizarre parosteal osteochondromatous proliferation and osteochondroma enriched in the TGFB signaling pathway ENSG00000137834 ENSG00000156574 ENSG00000134363 ENSG00000067900 ENSG00000205250 ENSG00000137801 ENSG00000170365 ENSG00000111537 ENSG00000095739 ENSG00000100387 ENSG00000198742 ENSG00000113558 ENSG00000185591 PMC7332497__F3 Cytosolic and sub-cellular engineering of yeast for isoprenoids biosynthesis ENSG00000067064 ENSG00000196839 ENSG00000197429 PMC3659771__F1 Notch signaling in the vasculature ENSG00000168214 ENSG00000283780 ENSG00000128917 ENSG00000148400 ENSG00000074181 ENSG00000100060 ENSG00000184916 ENSG00000090932 ENSG00000106003 PMC7952454__F3 DNASE2A deficiency causes an accumulation of phagocytosed dsDNA as well as nuclear dsDNA transported by autophagy into endolysosomal compartments ENSG00000166428 ENSG00000239732 ENSG00000164430 ENSG00000111537 ENSG00000163568 ENSG00000125538 ENSG00000172936 ENSG00000105223 PMC3659771__F2 Notch signaling in the vasculature ENSG00000196411 ENSG00000176692 ENSG00000148400 ENSG00000112715 PMC6186458__F1 BH3-Dependent and Independent Activation of BAX and BAK in Mitochondrial Apoptosis ENSG00000168040 PMC9686795__F1 Link between Oxidative Stress, Mitochondrial Dysfunction and Neuroinflammation in the Pathophysiology of Alzheimer’s Disease: Therapeutic Implications and Future Perspectives ENSG00000177169 ENSG00000110497 ENSG00000188554 ENSG00000123395 ENSG00000126775 ENSG00000158828 ENSG00000214253 PMC5705532__F1 Signaling involving TLR2 and TLR4 in strenuous and moderate aerobic exercise ENSG00000198793 ENSG00000136869 ENSG00000168610 PMC2360544__F2 Novel therapeutic targets and proposed mechanisms of androgen resistance (text in red) in hormone refractory prostate cancer ENSG00000198793 ENSG00000184012 ENSG00000160710 PMC9478452__F1 Current perspectives on interethnic variability in multiple myeloma: Single cell technology, population pharmacogenetics and molecular signal transduction ENSG00000104856 ENSG00000134982 ENSG00000155792 ENSG00000168036 ENSG00000164327 ENSG00000111321 ENSG00000127191 ENSG00000168610 ENSG00000096395 ENSG00000136997 ENSG00000123374 ENSG00000131323 ENSG00000128342 ENSG00000083799 ENSG00000140443 PMC6205911__F1 Post-squalene cholesterol biosynthetic pathway and examples of malformation disorders associated with defects at specific steps ENSG00000001630 ENSG00000116133 ENSG00000172893 PMC4064721__F1 Scheme of participation of MC1R in regulation of melanogenesis ENSG00000102858 ENSG00000141480 ENSG00000101440 ENSG00000170262 PMC4765532__F2 BMP signaling pathway including microRNA regulation ENSG00000170365 ENSG00000137834 PMC4064721__F2 Scheme of the impact of MC1R on development of melanoma ENSG00000157764 ENSG00000291971 ENSG00000169439 PMC4765532__F3 Wnt signaling pathway including microRNA regulation ENSG00000281324 ENSG00000162337 ENSG00000134569 ENSG00000134982 ENSG00000167941 ENSG00000291748 ENSG00000168036 ENSG00000108821 PMC8648396__F10 Matrix metalloproteinases and tissue inhibitors of metalloproteinases in murine Beta-coronavirus-induced neuroinflammation ENSG00000173039 PMC8395092__F2 Immunometabolic Roles of Various Fatty Acids in Macrophages and Lymphocytes ENSG00000134982 ENSG00000186716 PMC4986885__F3 SRSF1's roles in transformation in breast cancer ENSG00000167325 ENSG00000136997 ENSG00000171848 PMC5620176__F9 LncRNA ANCR down-regulation promotes TGF-Beta-induced EMT and metastasis in breast cancer ENSG00000171720 PMC3840000__F1 A Potential Benefit of Albinism in Astyanax Cavefish: Downregulation of the oca2 Gene Increases Tyrosine and Catecholamine Levels as an Alternative to Melanin Synthesis ENSG00000188467 ENSG00000080166 ENSG00000107165 PMC8597301__F8 Fecal microbiota transplantation protects rotenone-induced Parkinson’s disease mice via suppressing inflammation mediated by the lipopolysaccharide-TLR4 signaling pathway through the microbiota-gut-brain axis ENSG00000172936 ENSG00000136869 PMC6320319__F1 Schematic summary of the Wnt signaling derangements and the different traits of metabolic syndrome ENSG00000281324 ENSG00000042832 ENSG00000185591 PMC5986049__F1 Control of erythropoietin (EPO) synthesis by the oxygen sensing pathway ENSG00000134086 PMC4797366__F3 Wnt signalling in energy balance regulation ENSG00000281324 ENSG00000168646 PMC7122459__F1 Molecular signaling pathways involved in astrocytogenesis ENSG00000125398 ENSG00000242689 ENSG00000128342 ENSG00000162599 PMC3430392__F1 The function of CETP in RCT.Notes: CETP mediates the equimolar transfer of CE and TG between atherogenic VLDL, LDL, and anti-atherogenic HDL ENSG00000042832 PMC7369697__F1 BRAF signaling pathway including abnormal signaling from BRAFV600E mutated proteins ENSG00000002330 ENSG00000157764 PMC11134594__F2 TGFB signaling pathway: Integrins release TGFB by binding to LLC on ECM PMC7065707__F4 Cell cycle in stem cell proliferation, pluripotency and differentiation ENSG00000114315 ENSG00000080839 ENSG00000175305 PMC7065707__F2 Cell cycle in stem cell proliferation, pluripotency and differentiation ENSG00000123374 ENSG00000139687 PMC3281554__F2 Possible mechanisms of regulation of DP thymocytes by multiple factors ENSG00000168036 ENSG00000283060 PMC11892258__F3 Mechanism of immunosenescence promoting tumor occurrence and development ENSG00000163464 ENSG00000105835 ENSG00000096717 PMC5192802__F2 Roles of nucleus PRDX1 in the H2O2‐induced apoptosis PMC6928143__F5 Wnt signaling pathway was involved in NFPA ENSG00000175206 ENSG00000070831 ENSG00000134982 ENSG00000168036 PMC6928143__F6 ERK-MAPK signaling pathway was involved in NFPA ENSG00000172680 ENSG00000002330 ENSG00000291971 ENSG00000136997 ENSG00000089159 PMC3590201__F1 Identification of Pathway Markers in Intracranial Aneurysm Using Genome-Wide Association Data from Two Different Populations ENSG00000087095 ENSG00000147862 ENSG00000179091 ENSG00000138798 ENSG00000177606 ENSG00000130159 ENSG00000081189 PMC4097957__F1 TLR4 signaling pathway ENSG00000183735 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC4770718__F1 PPE26 induces TLR2-dependent activation of macrophages and drives Th1-type T-cell immunity by triggering the cross-talk of multiple pathways involved in the host response ENSG00000162889 ENSG00000104365 ENSG00000102908 ENSG00000109320 ENSG00000135090 ENSG00000140968 ENSG00000169032 ENSG00000183735 ENSG00000115415 ENSG00000170458 ENSG00000141480 ENSG00000172936 ENSG00000175104 PMC9130030__F1 Realigning the LIGHT signaling network to control dysregulated inflammation ENSG00000111321 PMC6928143__F3 PI3K-AKT signaling pathway was involved in NFPA ENSG00000002330 ENSG00000105401 ENSG00000198793 PMC4146642__F7 ABeta(1-42) oligomer-induced oxidative stress ENSG00000127445 PMC7692354__F1 Near-infrared (NIR)-triggered photothermal action in MDA-MB-231 and MCF7 cell lines: the illustration shows irinotecan hydrochloride (IT) on-demand release from irinotecan-loaded biotinylated carbon nanodots (CDs-PEG-BT/IT) by means of hyperthermia ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000057663 ENSG00000076604 ENSG00000082512 ENSG00000144848 ENSG00000131323 ENSG00000120868 ENSG00000083799 ENSG00000168404 ENSG00000285379 PMC6928143__F4 mTOR signaling pathway was involved in NFPA ENSG00000157554 ENSG00000163914 ENSG00000164327 PMC8151911__F2 Mechanism of Asparagine Endopeptidase in the Progression of Malignant Tumors: A Review ENSG00000145321 ENSG00000175104 ENSG00000168610 ENSG00000164949 PMC11056900__F1 Molecular mechanism of mitochondrial dysfunction modulating the relationship between chronic liver disease ENSG00000162711 ENSG00000164430 ENSG00000115415 ENSG00000156026 ENSG00000142082 PMC11056900__F2 Endoplasmic reticulum dysfunction modulates chronic liver disease ENSG00000128272 ENSG00000144895 ENSG00000125538 ENSG00000100219 PMC11056900__F3 Mitochondrial and endoplasmic reticulum-associated signaling regulates the molecular mechanism of chronic liver disease ENSG00000116688 ENSG00000047936 ENSG00000171109 PMC6169299__F8 Signalling pathways in the TLR response ENSG00000169245 ENSG00000183735 ENSG00000170458 ENSG00000138755 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000276561 ENSG00000184216 ENSG00000277943 ENSG00000164342 PMC7990044__F3 Genetic modifications designed to address xenograft injury mechanisms ENSG00000069482 ENSG00000198053 ENSG00000134982 PMC8549681__F1 Glucocorticoids induce osteonecrosis of the femoral head through the Hippo signaling pathway ENSG00000150457 ENSG00000131023 PMC8389838__F5 Targeting Small GTPases and Their Prenylation in Diabetes Mellitus ENSG00000070831 ENSG00000149269 ENSG00000006451 ENSG00000169047 ENSG00000136111 PMC7210546__F4 Possible cross-regulation of RAS and TLR4 in mediating the inflammation of DN ENSG00000172936 ENSG00000136869 PMC7210546__F1 TLRs and signaling molecules on the basis of literatures ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC7210546__F2 TLR4 signaling pathway in the DN on the basis of literatures ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC4323418__F7 Map of central carbon metabolism highlighting CceR and AkgR targets ENSG00000122966 ENSG00000172005 PMC5481839__F6 DOT1L safeguards cartilage homeostasis and protects against osteoarthritis ENSG00000109819 ENSG00000138795 ENSG00000104885 ENSG00000096717 PMC7073516__F2 Fast and slow routes to break-induced telomere synthesis ENSG00000132646 ENSG00000163918 ENSG00000051180 ENSG00000077514 ENSG00000035928 ENSG00000121211 ENSG00000133119 PMC10605176__F3 Noble gas-induced neuroprotection ENSG00000136869 PMC6536925__F6 Relationship of the three diseases at gene, pathway, module, and function levels and the biological mechanism of T2DM, CML, and PCa ENSG00000198793 ENSG00000173599 ENSG00000170624 PMC8087798__F8 Mechanism of POU2F2 regulates glycolytic reprogramming and GBM progression ENSG00000140992 ENSG00000028277 ENSG00000198793 ENSG00000159399 PMC10605176__F1 Neuroprotection by the volatile anesthetics sevoflurane and isoflurane ENSG00000136869 ENSG00000185591 ENSG00000168610 PMC6775191__F8 Network visualization analysis of “potential lipid markers-lipoproteins-TLR4/MyD88 signaling pathways” for anti-inflammatory effects of HLJDD ENSG00000135218 ENSG00000127472 ENSG00000109956 ENSG00000135587 ENSG00000138308 ENSG00000184381 ENSG00000170890 ENSG00000100422 ENSG00000198964 ENSG00000111796 ENSG00000158786 ENSG00000188257 ENSG00000243708 ENSG00000276870 ENSG00000125538 ENSG00000100078 ENSG00000164023 ENSG00000172936 ENSG00000079435 ENSG00000133027 PMC7944035__F1 TLRs multiple signaling pathways ENSG00000162711 ENSG00000170365 ENSG00000272398 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC4214202__F1 Simplified model of the potential contributions of selective sensors and cell types to IFN production during viral infections ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000173578 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC11983764__F1 BCAA metabolism and tumours ENSG00000060982 ENSG00000103507 ENSG00000291917 ENSG00000160785 ENSG00000105552 ENSG00000163644 PMC11983764__F2 BCAA hypocatabolism promotes tumour development ENSG00000108523 ENSG00000131473 ENSG00000138134 ENSG00000060982 ENSG00000103507 ENSG00000160785 ENSG00000105552 ENSG00000117399 ENSG00000143995 PMC3249369__F4 Three MAPK pathways in yeast share common components and also contain pathway-specific factors ENSG00000070831 ENSG00000163914 PMC5428537__F1 Meta Core pathway analysis indicated that cardiac hypertrophy signaling was significantly associated with sesamin-treated samples (P=1.148E-10) ENSG00000113196 ENSG00000291507 ENSG00000285109 ENSG00000134982 ENSG00000164107 ENSG00000138741 ENSG00000081189 PMC5514220__F2 Involvement of sirtuins in lifespan/healthspan elongation pathways ENSG00000105835 ENSG00000198793 PMC4019040__F1 Mutated and wild-type tyrosine kinase activation in cancer ENSG00000186716 ENSG00000077782 ENSG00000146648 ENSG00000010671 PMC4093113__F2 Pathway analysis of the candidate genes ENSG00000180210 ENSG00000151657 PMC2685579__F1 Synthetic pathways for polar lipids ENSG00000173599 ENSG00000184207 PMC9217774__F3 Serial Tumor Molecular Profiling of Newly Diagnosed HER2-Negative Breast Cancers During Chemotherapy in Combination with Angiogenesis Inhibitors ENSG00000175054 ENSG00000157404 PMC11084561__F3 Two consecutive signals are requisite for inflammasome activation ENSG00000278718 ENSG00000162711 ENSG00000163568 PMC4394821__F1 Folate biosynthesis and utilization pathway (modified from reference ) ENSG00000228716 ENSG00000095059 ENSG00000136877 PMC8261820__F3 Signal pathways and treatment of cytokine storm in COVID-19 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000130234 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC3883350__F1 VIP tunes immune and inflammatory response by regulating multiple signaling pathways ENSG00000111537 ENSG00000115415 ENSG00000163599 ENSG00000146469 ENSG00000177606 ENSG00000136869 ENSG00000049768 ENSG00000125347 PMC4963239__F4 Mediator complex: a central integrator of transcription ENSG00000042429 ENSG00000184634 ENSG00000168036 ENSG00000172936 ENSG00000131323 ENSG00000276561 PMC3834244__F1 MiRNA biogenesis and function ENSG00000100697 ENSG00000092847 ENSG00000128191 ENSG00000113360 ENSG00000134698 ENSG00000123908 PMC3652852__F7 Peroxisome Proliferator-Activated Receptor (PPAR) G and PPARA Agonists Modulate Mitochondrial Fusion-Fission Dynamics: Relevance to Reactive Oxygen Species (ROS)-Related Neurodegenerative Disorders? ENSG00000134982 PMC12148668__S1 Schematic diagram illustrates the preparation of IFNG treated RAW 264 ENSG00000125538 ENSG00000145321 ENSG00000188158 PMC3623586__F2 Schematic model of the regulation of intestinal homeostasis by the IL-22/STAT3 pathway in IECs ENSG00000105397 ENSG00000168610 PMC9187046__F1 GSK-3 regulates PD-1 and LAG3 expression for enhanced T-cell reactivity ENSG00000089692 ENSG00000168036 PMC8593497__F1 Metformin on Hepatic Steatosis in Adults with Nonalcoholic Fatty Liver Disease and Diabetes: Insights from the Cellular to Patient Levels ENSG00000067900 ENSG00000099194 ENSG00000096717 PMC7291227__F4 Ingenuity Pathway Analysis (IPA) upstream regulatory analysis ENSG00000139219 ENSG00000183734 ENSG00000125398 ENSG00000169562 ENSG00000136997 ENSG00000164362 ENSG00000112118 ENSG00000137880 ENSG00000167034 ENSG00000089225 ENSG00000106829 ENSG00000143387 PMC7291227__F3 Ingenuity Pathway Analysis (IPA) gene network analysis ENSG00000177694 ENSG00000115761 ENSG00000265354 ENSG00000112561 ENSG00000171206 ENSG00000146457 ENSG00000070669 ENSG00000153814 ENSG00000125398 ENSG00000136997 ENSG00000184012 ENSG00000137880 ENSG00000278270 ENSG00000136878 ENSG00000136816 ENSG00000197576 ENSG00000134013 ENSG00000171861 ENSG00000095261 ENSG00000163584 ENSG00000206538 ENSG00000187257 ENSG00000120438 ENSG00000147874 ENSG00000100294 ENSG00000166938 ENSG00000175792 PMC5533267__F6 Glabridin on the estrogen pathway ENSG00000082175 ENSG00000185591 PMC4414696__F3 Simplified TAM signaling pathways in supporting cell proliferation and survival (A) and inhibiting inflammation (B) PMC3866828__F3 HVJ-E-mediated apoptosis pathway in cancer cells ENSG00000132906 ENSG00000088888 ENSG00000064012 ENSG00000164305 ENSG00000276561 PMC4612381__F6 Elevated Endoplasmic Reticulum Stress Response Contributes to Adipose Tissue Inflammation in Aging ENSG00000134109 ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC5711482__F1 Targeting polyamine metabolism for cancer therapy and prevention ENSG00000088826 ENSG00000148832 PMC8295747__F2 Harnessing the Activation of RIG-I Like Receptors to Inhibit Glioblastoma Tumorigenesis ENSG00000183735 ENSG00000088888 ENSG00000125347 ENSG00000164305 ENSG00000276561 PMC8589328__F1 Substrate, intermediates and enzymes involved in the endogenous production and disposal of H2S ENSG00000205221 ENSG00000139531 PMC10531041__F2 Stress Response in Autophagy Processes and Aging-Related Diseases ENSG00000152137 ENSG00000151929 PMC11584093__F4 Anti-cancer signalling pathways modulated by curcumin, gingerol, and shogaol in cervical cancer cells ENSG00000168036 ENSG00000146648 PMC7810546__F7 Compound-target-pathway network ENSG00000157404 ENSG00000291971 ENSG00000181104 ENSG00000172572 ENSG00000165280 ENSG00000158517 ENSG00000173391 ENSG00000171791 ENSG00000135914 ENSG00000144476 ENSG00000180210 ENSG00000149968 ENSG00000263528 ENSG00000128052 ENSG00000027075 ENSG00000262406 ENSG00000142192 ENSG00000157764 ENSG00000120915 ENSG00000162551 ENSG00000131747 ENSG00000007908 ENSG00000073756 ENSG00000007171 ENSG00000132170 ENSG00000186810 ENSG00000067606 ENSG00000177606 ENSG00000057593 ENSG00000164362 ENSG00000005381 PMC9272595__F8 Oncogenic receptor tyrosine kinase pathway with its downstream signaling pathways and small molecule inhibitors targeting different proteins of the network ENSG00000167601 ENSG00000198793 ENSG00000047936 ENSG00000146648 PMC11899589__F7 Schematic representation illustrating the mechanism of action of erianin in lung cancer ENSG00000198793 ENSG00000102967 ENSG00000084774 PMC4825669__F6A Differential Role of G Protein-Coupled Receptor Kinase 5 in Physiological Versus Pathological Cardiac Hypertrophy ENSG00000121903 ENSG00000159200 ENSG00000125414 ENSG00000150991 ENSG00000172216 ENSG00000106245 ENSG00000274334 ENSG00000050165 ENSG00000168610 ENSG00000081189 ENSG00000264424 ENSG00000106631 PMC8949908__F5 Betaine Supplementation Causes an Increase in Fatty Acid Oxidation and Carbohydrate Metabolism in Livers of Mice Fed a High-Fat Diet: A Proteomic Analysis ENSG00000197713 ENSG00000145912 ENSG00000276559 ENSG00000117054 ENSG00000108679 ENSG00000117601 ENSG00000241935 ENSG00000161533 ENSG00000283391 ENSG00000288475 ENSG00000257727 ENSG00000099800 ENSG00000106554 ENSG00000158874 ENSG00000116771 ENSG00000055044 ENSG00000159650 ENSG00000124177 PMC10139027__F5 Scheme of LDLR activity signaling pathway for follicular development with lovastatin stimulates steroidogenesis in ovaries ENSG00000130164 PMC8362328__F10 Upregulation of KLK8 Predicts Poor Prognosis in Pancreatic Cancer ENSG00000129455 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8268639__F1 NUAK1 and NUAK2 Fine-Tune TGFB Signaling ENSG00000074590 PMC7295848__F1 PI3K/AKT signaling cascades in cancers ENSG00000173599 ENSG00000136997 ENSG00000145321 ENSG00000121879 PMC8133338__F1 Erythropoietin in bone homeostasis—Implications for efficacious anemia therapy ENSG00000177455 PMC5732365__F1 Rho GTPases and AD pathology ENSG00000142192 ENSG00000163914 PMC1878539__F1 Unchecked thrombin is bad news for troubled arteries ENSG00000003436 ENSG00000134982 PMC6172470__F1 Translation acrobatics: how cancer cells exploit alternate modes of translational initiation ENSG00000163435 ENSG00000120690 ENSG00000144895 PMC8219921__F1 Long Non-Coding RNAs in Conferring Resistance in Tumors of the Nervous System ENSG00000169554 ENSG00000011304 ENSG00000134982 ENSG00000168036 ENSG00000146648 PMC3674397__F2 Mechanisms of activity for sirtuins in Alzheimer's disease ENSG00000142192 ENSG00000067900 ENSG00000137845 PMC12155304__F4 Sinhyotaklisan as a Potential Therapeutic for Psoriasis: Network Pharmacology and Experimental Validation ENSG00000115008 ENSG00000105329 ENSG00000116044 ENSG00000138798 ENSG00000173039 ENSG00000168036 ENSG00000171791 ENSG00000073756 ENSG00000168610 ENSG00000164305 ENSG00000132170 ENSG00000163631 ENSG00000108691 ENSG00000111537 ENSG00000177606 ENSG00000136997 ENSG00000125538 ENSG00000100985 ENSG00000146648 PMC6193563__F3 Metabolic reprogramming of the tumor microenvironment by p62 and its partners ENSG00000188554 ENSG00000175104 ENSG00000079999 PMC9061988__F1 Mathematical Modeling of Complement Pathway Dynamics for Target Validation and Selection of Drug Modalities for Complement Therapies ENSG00000039537 ENSG00000113600 ENSG00000062485 PMC8888691__F5 Microglia and Astrocyte Function and Communication: What Do We Know in Humans? ENSG00000174125 ENSG00000108691 ENSG00000239732 ENSG00000091972 ENSG00000187554 ENSG00000183625 ENSG00000136869 ENSG00000121807 ENSG00000277943 ENSG00000164342 PMC8020258__F6 Osthole inhibits macrophage activation in an experimental model of asthma (schematic) ENSG00000113520 ENSG00000118520 PMC4964517__F4 Upregulation of melanogenesis by SOX9 ENSG00000125398 ENSG00000080166 PMC9495336__F3 Fucoidan from Marine Macroalgae: Biological Actions and Applications in Regenerative Medicine, Drug Delivery Systems and Food Industry ENSG00000151012 ENSG00000096717 ENSG00000079999 PMC6668978__F10 Schematic diagram shows the interplay of TGFB1, Notch, Shh signalling and Foxa in antler chondrocyte proliferation and differentiation ENSG00000105329 ENSG00000148400 ENSG00000164690 ENSG00000128602 PMC4590922__F4 The calgranulins, S100A8, S100A9, and S100A12, are secreted by cells of the myeloid lineage such as neutrophils and monocytes ENSG00000143546 ENSG00000163220 ENSG00000163221 ENSG00000136869 PMC6419612__F1 Metastatic progression in the bone ENSG00000107562 PMC6056224__F1 Imbalanced expression/ activity of RAD18 and Y-family DNA polymerases dictates choice of TLS polymerases and can influence replication fidelity and genome stability ENSG00000101751 ENSG00000147381 ENSG00000070950 ENSG00000130997 ENSG00000122008 PMC9577232__F6 Targeting the cannabinoid system to counteract the deleterious effects of stress in Alzheimer’s disease ENSG00000168036 PMC6173361__F3 Comparative proteomic analysis of cat eye syndrome critical region protein 1- function in tumor-associated macrophages and immune response regulation of glial tumors ENSG00000224320 ENSG00000005893 ENSG00000232326 ENSG00000127022 ENSG00000273686 ENSG00000231925 ENSG00000105402 ENSG00000105669 ENSG00000110719 PMC3795238__F8 A model depicting androgen-AR-miR-29a regulation loop ENSG00000070831 PMC5729470__F1 Differences in pathway activation between left-sided vs right-sided CRC ENSG00000105397 ENSG00000065361 ENSG00000291971 ENSG00000134982 ENSG00000168646 ENSG00000168610 ENSG00000196628 PMC8456978__F2 New insights into the molecular mechanisms of axon guidance receptor regulation and signaling ENSG00000170381 ENSG00000122882 ENSG00000125848 ENSG00000182175 ENSG00000142192 ENSG00000198799 ENSG00000116106 ENSG00000291971 ENSG00000166278 ENSG00000133216 PMC8224569__F6 Global Transcriptional Response of Aspergillus niger to Blocked Active Citrate Export through Deletion of the Exporter Gene ENSG00000115850 ENSG00000122966 ENSG00000062485 PMC5823535__F1 Lessons from characterization and treatment of the inflammatory syndromes ENSG00000162711 ENSG00000137275 ENSG00000102871 ENSG00000154124 ENSG00000127191 PMC7596324__F1 Mitochondria-targeted Therapies ENSG00000163599 ENSG00000198793 PMC6045629__F9 Mechanism of coagonism ENSG00000291603 ENSG00000213658 ENSG00000113263 PMC4716086__F1 Homeostasis and epidermal growth factor receptor downstream signaling pathway in keratinocyte ENSG00000109321 ENSG00000163235 ENSG00000124882 ENSG00000113070 ENSG00000146648 PMC8612614__F3 Dysfunction of the Blood-brain Barrier in Cerebral Microbleeds: from Bedside to Bench ENSG00000132693 PMC2947835__F2 Membrane proximal intracellular signals at the IS versus the HIV VS ENSG00000213658 ENSG00000124181 PMC2704867__F5 Darpp-32 and Its Truncated Variant t-Darpp Have Antagonistic Effects on Breast Cancer Cell Growth and Herceptin Resistance ENSG00000005882 ENSG00000146648 PMC8219171__F5 An Examination of the Putative Role of Melatonin in Exosome Biogenesis ENSG00000152348 ENSG00000167461 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC8219171__F6 An Examination of the Putative Role of Melatonin in Exosome Biogenesis ENSG00000281324 ENSG00000162337 ENSG00000288174 ENSG00000070770 ENSG00000104290 ENSG00000075891 ENSG00000197943 ENSG00000137764 ENSG00000125084 ENSG00000106829 PMC6880659__F5 Proposed model of TFC pyroptosis in excessive iodine-promoted HT ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC3884575__F2 Schematic representation of complement-mediated effects on T cells and APCs ENSG00000111537 ENSG00000134982 PMC12046282__F1 After CNPs enter cells through endocytosis, they induce the expression of TNFA and BMP2 ENSG00000162711 ENSG00000100219 ENSG00000168610 PMC3096194__F1 Cell cycle is controlled by the Rb pathway and p53 pathway ENSG00000135446 ENSG00000123374 PMC3663521__F7 Schematic diagram illustrates the role of Dapper3 in UUO-induced renal fibrosis by regulating Wnt/Beta-catenin signaling ENSG00000112977 ENSG00000281324 ENSG00000137673 ENSG00000162337 ENSG00000168036 ENSG00000168646 PMC6709804__F2 Mechanism of response mediated by M1, M2, and M4 macrophages ENSG00000262406 ENSG00000137673 ENSG00000115415 ENSG00000113520 ENSG00000136869 ENSG00000118520 ENSG00000105639 ENSG00000168610 PMC8415634__F1 Emerging Mechanisms of Wnt Secretion and Signaling in Development ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5315281__F5 De novo assembly of the sea trout (Salmo trutta m. trutta) skin transcriptome to identify putative genes involved in the immune response and epidermal mucus secretion ENSG00000288368 ENSG00000158470 ENSG00000198488 PMC2063509__F1 AUTOPHAGY: HIGHLIGHTING A NOVEL PLAYER IN THE AUTOIMMUNITY SCENARIO ENSG00000198793 ENSG00000144848 ENSG00000113520 PMC8415634__F2 Emerging Mechanisms of Wnt Secretion and Signaling in Development ENSG00000112335 ENSG00000167461 PMC2491722__F4 Gdnf signaling pathways within the mammalian spermatogonial stem cell niche ENSG00000291971 PMC2491722__F6 Gdnf signaling pathways within the mammalian spermatogonial stem cell niche ENSG00000123374 ENSG00000123268 PMC7068464__F7 Schematic diagram showing that upregulation of large-conductance and Ca2+-activated K+ (BK) channel activity in activated hepatic stellate cells (HSCs) exerts an antifibrotic effect through suppressing of the profibrotic TGFB1 signaling pathway ENSG00000168610 ENSG00000156113 PMC5558548__F5 Sphingolipids as targets for treatment of fungal infections ENSG00000100422 ENSG00000147869 ENSG00000128052 ENSG00000173599 ENSG00000102172 ENSG00000135517 PMC7846556__F1 Inhibition of gasdermin D-mediated pyroptosis by necrosulfonamide, disulfiram, and dimethyl fumarate ENSG00000278718 ENSG00000125538 PMC11294427__F2 S100A9 binds to Toll‐like receptor 4 (TLR4) to activate downstream pathways for biological effects ENSG00000162711 ENSG00000163220 ENSG00000163914 ENSG00000172936 ENSG00000136869 PMC2265304__F1 Idiopathic Pulmonary Fibrosis: Aberrant Recapitulation of Developmental Programs? ENSG00000170365 PMC11294427__F3 The S100A9‐receptor for advanced glycation end products (RAGE) signalling pathway in cardiovascular disease ENSG00000163220 PMC4619615__F7 Structure-Activity Relationship of Synthetic 2-Phenylnaphthalenes with Hydroxyl Groups that Inhibit Proliferation and Induce Apoptosis of MCF-7 Cancer Cells ENSG00000134057 ENSG00000135446 ENSG00000123374 ENSG00000026103 PMC11616179__F2 Liver macrophages in liver fibrosis repair ENSG00000262406 ENSG00000100985 ENSG00000168610 PMC11616179__F3 LAMs and LCMs in liver injury ENSG00000162711 ENSG00000168329 ENSG00000116688 ENSG00000121807 PMC11616179__F1 Liver macrophage in the initiation and progression of liver fibrosis ENSG00000108702 ENSG00000162711 ENSG00000179934 ENSG00000108691 ENSG00000134013 ENSG00000189403 ENSG00000100985 ENSG00000121807 PMC8146072__F13 Metabolic Reprogramming in Cancer Cells Supporting Enhanced Growth and Proliferation ENSG00000002330 ENSG00000164305 PMC7998928__F1 Detrimental role of Formyl Peptide Receptor 1 (FPR1) in CVDs progression ENSG00000125538 ENSG00000171051 PMC8146072__F10 Metabolic Reprogramming in Cancer Cells Supporting Enhanced Growth and Proliferation ENSG00000284320 ENSG00000228716 ENSG00000065911 ENSG00000128272 ENSG00000092621 ENSG00000146733 ENSG00000178445 ENSG00000116984 PMC5891988__F2 ILC3s in the context of cancer ENSG00000226275 ENSG00000168610 PMC11915259__F3 Microbiota disruption leading to an inflammatory environment ENSG00000198793 ENSG00000136869 PMC8281348__F9 Regulation and mechanism of YAP/TAZ in the mechanical microenvironment of stem cells ENSG00000178860 ENSG00000167601 ENSG00000110711 ENSG00000149930 ENSG00000160551 ENSG00000135090 ENSG00000171444 ENSG00000150457 ENSG00000131023 PMC3511325__F9 Protective Role of STAT3 in NMDA and Glutamate-Induced Neuronal Death: Negative Regulatory Effect of SOCS3 ENSG00000168610 PMC3279615__F3 Nucleotide excision repair (NER) pathway ENSG00000012061 ENSG00000108582 ENSG00000132646 ENSG00000136936 PMC4587803__F3 NF KB signalling pathway ENSG00000039537 ENSG00000244731 ENSG00000166278 PMC4610626__F2 Multiple activating human natural killer (NK) cell receptors and representative signalling pathways of 2B4, NKG2D, DNAM-1 and NKp46/30 ENSG00000291603 ENSG00000213658 ENSG00000291971 ENSG00000149269 ENSG00000134215 ENSG00000160293 ENSG00000141968 PMC7272438__F8 Proposed model for the involvement of miR-199a-3p and CAV2 in hepatic fibrosis PMC4709508__F3 Toll-like receptors, adapter proteins, and signaling molecules ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC6930809__F12 Potential mechanisms by which Meisoindigo protects against focal cerebral ischemia-reperfusion injury (CIRI) ENSG00000162711 ENSG00000170458 ENSG00000125538 ENSG00000136869 PMC2771724__F3 Dopamine Receptor Signaling: Genes differentially expressed in the NAC of LE vs ENSG00000106617 ENSG00000184845 ENSG00000149295 PMC2771724__F4 Synaptic Long-Term Potentiation: Genes differentially expressed in the NAC of LE vs ENSG00000106617 PMC6769439__F8 Possible mechanism of action underlying the protective effects of maltol against APAP-induced hepatic injury through inhibition of oxidative stress-mediated activation of the NFKB pathway and apoptosis and regulation of the PI3K/Akt pathway ENSG00000132906 ENSG00000142192 ENSG00000102871 ENSG00000168040 ENSG00000064012 ENSG00000164305 PMC7530368__F2 Mitochondrial dysfunction in kidney injury, inflammation, and disease: potential therapeutic approaches ENSG00000164430 ENSG00000111537 ENSG00000125538 ENSG00000086991 ENSG00000285379 PMC2584809__F6 Schematic model illustrating constitutive vs ENSG00000163618 ENSG00000123454 ENSG00000141744 ENSG00000132639 PMC8301439__F3 IDH Mutations in Glioma: Double-Edged Sword in Clinical Applications? ENSG00000105835 ENSG00000060982 ENSG00000134853 ENSG00000105552 ENSG00000115419 PMC9228918__F7 ATM Pathway Is Essential for HPV–Positive Human Cervical Cancer-Derived Cell Lines Viability and Proliferation ENSG00000149311 ENSG00000012048 ENSG00000183765 PMC8616386__F2 Walking down Skeletal Muscle Lane: From Inflammasome to Disease ENSG00000278718 ENSG00000162711 ENSG00000088888 ENSG00000125538 ENSG00000265972 PMC7641865__F8 The protective effects of hPMSCs on CD4+ T cells senescence ENSG00000181019 ENSG00000010810 PMC9317022__F1 Innate Immunity Crosstalk with Helicobacter pylori: Pattern Recognition Receptors and Cellular Responses ENSG00000183735 ENSG00000239732 ENSG00000167207 ENSG00000187796 ENSG00000187554 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC5462452__F1 ROS in Cancer: The Burning Question ENSG00000065833 ENSG00000100714 ENSG00000105227 PMC8616386__F6 Walking down Skeletal Muscle Lane: From Inflammasome to Disease ENSG00000278718 ENSG00000162711 ENSG00000159346 ENSG00000136869 ENSG00000121853 PMC2670105__F1 IMP impedes Ras mitogenic signaling by limiting KSR1 complexes ENSG00000157764 ENSG00000138798 ENSG00000141068 PMC3031545__F8 Regulation of Brown Fat Adipogenesis by Protein Tyrosine Phosphatase 1B ENSG00000026103 PMC4905708__F2 Coinhibitory pathways in the B7-CD28 ligand-receptor family ENSG00000134982 ENSG00000198589 PMC9024145__F3 Non-Coding RNAs in Sepsis-Associated Acute Kidney Injury ENSG00000107562 ENSG00000163558 ENSG00000136869 ENSG00000253352 ENSG00000102178 ENSG00000121966 PMC6891441__F1 Scheme of Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) function in the cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) pathway ENSG00000183735 ENSG00000164430 ENSG00000197594 ENSG00000174840 PMC11034130__F2 Lipid metabolism in tumor-infiltrating regulatory T cells: perspective to precision immunotherapy ENSG00000138378 ENSG00000135218 ENSG00000152904 ENSG00000163599 ENSG00000150907 ENSG00000049768 ENSG00000168522 ENSG00000026103 PMC4139724__F3 Functional features of gingivitis-associated microbiota ENSG00000151702 ENSG00000182263 PMC6720954__F1 Upper, matrix metalloproteinase 1 (MMP1) cleavage of protease-activated receptors (PARs) result in increased Ca2+signaling ENSG00000019582 ENSG00000164151 ENSG00000262406 ENSG00000087245 ENSG00000081041 ENSG00000111537 ENSG00000137673 ENSG00000108688 ENSG00000142166 ENSG00000026103 PMC2928401__F8 Identification of Primary Gene Targets of TFAP2C in Hormone Responsive Breast Carcinoma Cells ENSG00000132478 ENSG00000160691 ENSG00000102977 ENSG00000196411 ENSG00000005810 ENSG00000073060 ENSG00000084676 ENSG00000100714 ENSG00000292234 ENSG00000143320 ENSG00000136997 ENSG00000291837 ENSG00000196352 ENSG00000115461 ENSG00000113494 PMC8773335__F5 Parkinson’s Disease and the Metal–Microbiome–Gut–Brain Axis: A Systems Toxicology Approach ENSG00000087245 ENSG00000213658 ENSG00000137674 ENSG00000156026 ENSG00000125538 ENSG00000166278 ENSG00000100985 PMC11792030__F1 CoQ biosynthetic pathway ENSG00000132423 ENSG00000167113 ENSG00000110871 ENSG00000197429 ENSG00000173085 PMC7160660__F3 Control of regulatory T‐cell differentiation and function by T‐cell receptor signalling and Foxp3 transcription factor complexes ENSG00000163624 ENSG00000159216 ENSG00000198793 ENSG00000162852 ENSG00000049768 PMC9214231__F3 Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe ENSG00000269964 ENSG00000123268 PMC10555542__F4 Glimepiride Compared to Liraglutide Increases Plasma Levels of miR-206, miR-182-5p, and miR-766-3p in Type 2 Diabetes Mellitus: A Randomized Controlled Trial ENSG00000135655 ENSG00000169031 ENSG00000146247 ENSG00000113161 ENSG00000171791 ENSG00000112715 ENSG00000121879 ENSG00000132639 ENSG00000285069 ENSG00000106546 ENSG00000220205 ENSG00000094841 ENSG00000084733 ENSG00000187210 ENSG00000251493 ENSG00000101333 ENSG00000163884 ENSG00000162896 PMC6986459__F1 Landscape of USP7 targets and modes of action.(a) The USP7–MDM2–p53 axis ENSG00000132109 ENSG00000148400 ENSG00000184481 PMC7686287__F6 Schematic summary of high glucose activated NFKB pathway ENSG00000087245 ENSG00000137673 ENSG00000125538 ENSG00000168610 PMC11034130__F3 Lipid metabolism in tumor-infiltrating regulatory T cells: perspective to precision immunotherapy ENSG00000134086 ENSG00000138378 ENSG00000135218 ENSG00000163599 ENSG00000150907 ENSG00000136997 ENSG00000162852 ENSG00000049768 PMC11034130__F4 Lipid metabolism in tumor-infiltrating regulatory T cells: perspective to precision immunotherapy ENSG00000139193 ENSG00000135218 ENSG00000163599 ENSG00000167468 ENSG00000049768 PMC8435685__F1 Adding a “Notch” to Cardiovascular Disease Therapeutics: A MicroRNA-Based Approach ENSG00000140564 ENSG00000168036 ENSG00000137845 ENSG00000128191 ENSG00000113360 PMC5343780__F1 Molecular mechanisms associated with inflammatory and oxidative stress in response to chronic exposure to PM0.1 ENSG00000073756 ENSG00000106546 ENSG00000079999 PMC12245507__F4 Ferroptosis signaling pathway ENSG00000167468 ENSG00000115107 ENSG00000115419 PMC8773522__F1 Impact of Cancer Cachexia on Cardiac and Skeletal Muscle: Role of Exercise Training ENSG00000198793 PMC4392874__F2 Network representations of the differentially expressed genes presented in pathway analysis ENSG00000163464 ENSG00000140992 ENSG00000291603 ENSG00000291971 ENSG00000169047 ENSG00000198793 ENSG00000203710 ENSG00000108443 ENSG00000171791 ENSG00000169032 ENSG00000112715 ENSG00000179295 ENSG00000136997 ENSG00000173578 ENSG00000124181 ENSG00000133818 ENSG00000124102 ENSG00000104689 ENSG00000117215 ENSG00000171105 ENSG00000101109 ENSG00000147168 ENSG00000078369 ENSG00000137070 ENSG00000106299 ENSG00000182621 ENSG00000132356 ENSG00000111537 ENSG00000110395 ENSG00000067606 ENSG00000143507 ENSG00000177606 ENSG00000146648 PMC5765207__F3 Developmentally regulated signaling pathways in glioma invasion ENSG00000019991 ENSG00000198793 ENSG00000168036 PMC9118284__F2 An overview of pharmacological activities of baicalin and its aglycone baicalein: New insights into molecular mechanisms and signaling pathways ENSG00000162711 ENSG00000087245 ENSG00000102871 ENSG00000125538 ENSG00000100985 ENSG00000150455 PMC9118284__F3 An overview of pharmacological activities of baicalin and its aglycone baicalein: New insights into molecular mechanisms and signaling pathways ENSG00000132906 ENSG00000168040 ENSG00000164305 PMC11923990__F9 Zbp1 Mediates central nervous system inflammation induced by AC via promoting macrophage inflammatory phenotypes ENSG00000169245 ENSG00000138755 PMC4971383__F1 Feedback loops that form the molecular clock ENSG00000105835 ENSG00000132326 ENSG00000096717 PMC11317487__F0 Graphical abstract and proposed pathway of rhMFGE8 administration attenuate hippocampal injury by improving neurogenesis in SAH models ENSG00000198793 ENSG00000077279 ENSG00000121905 ENSG00000140545 PMC5097173__F10 Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA ENSG00000132646 ENSG00000033800 ENSG00000070950 ENSG00000130997 PMC10813560__F8 Heatmaps were generated to visualise the notable pathways identified as significant by DIANA-miRPath (v ENSG00000002330 ENSG00000081051 PMC4345914__F2 TLR signaling pathway and modulation effector molecules ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC5737877__F8 Proposed model for the regulation of BATF3 by S1P signalling in HRS cells ENSG00000170989 ENSG00000285281 ENSG00000267534 PMC8263653__F14 Multi-organ metastasis as destination for breast cancer cells guided by biomechanical architecture ENSG00000143537 ENSG00000291971 ENSG00000168615 ENSG00000137845 ENSG00000148848 ENSG00000198363 PMC4142280__F4 Signaling crosstalk between the TGF-Beta-activated pathway and other pathways during EMT (according to Xu et al ENSG00000168036 PMC4630008__F1 Diagram of Hh signaling in mammalian cells ENSG00000214114 ENSG00000168283 ENSG00000180447 ENSG00000156076 ENSG00000112210 ENSG00000078747 ENSG00000144857 ENSG00000138798 ENSG00000171791 ENSG00000128602 ENSG00000118777 ENSG00000168610 PMC4350105__F7 Genome-wide DNA methylome analysis reveals epigenetically dysregulated non-coding RNAs in human breast cancer ENSG00000012048 ENSG00000101972 ENSG00000114126 ENSG00000136997 PMC4630008__F2 Different roles of Hh signaling in cancer ENSG00000198793 ENSG00000128602 PMC7027144__F3 Expression profiling of proteome reveals co-expression clusters and functional modules in HCC ENSG00000117054 ENSG00000122952 ENSG00000101003 ENSG00000109805 ENSG00000170430 ENSG00000115361 ENSG00000122971 ENSG00000166508 ENSG00000263238 PMC8622975__F3 Protective Effects of Equol (Soy Isoflavone Metabolite) on Coronary Heart Diseases—From Molecular Mechanisms to Studies in Humans ENSG00000102871 ENSG00000136869 ENSG00000121807 ENSG00000175104 PMC2660327__F2 Network analysis using Ingenuity pathway analysis (IPA) software ENSG00000002330 ENSG00000291971 ENSG00000128052 ENSG00000168036 ENSG00000171791 PMC1847380__F14 Signaling pathways leading to pseudohyphal growth ENSG00000175854 ENSG00000070831 ENSG00000130234 PMC1847380__F15 Signaling pathways mediating the roles of Rho1 in cell wall assembly and actin organization ENSG00000159263 ENSG00000149489 ENSG00000166278 PMC5377416__F11 Regulatory network construction for the overlapped genes ENSG00000264522 ENSG00000171914 ENSG00000163848 ENSG00000000971 ENSG00000099810 ENSG00000179094 ENSG00000138668 ENSG00000175104 ENSG00000112115 ENSG00000073756 ENSG00000198612 ENSG00000178568 PMC8908284__F3 Dualistic role of platelets in living donor liver transplantation: Are they harmful? ENSG00000019991 ENSG00000168610 PMC7049974__F1 Sterol reductases in cholesterol biosynthesis ENSG00000116133 ENSG00000143815 ENSG00000172893 PMC8047069__F2 Life Cycle of the Phagosome ENSG00000124102 ENSG00000102189 ENSG00000134108 PMC6097257__F7 Merged network analysis from Ingenuity Pathway Analysis (IPA) software for associations among molecules related to rheumatoid arthritis, inflammation of joint, cell cycle and apoptosis ENSG00000049323 ENSG00000137804 ENSG00000132031 ENSG00000107562 ENSG00000138316 ENSG00000165480 ENSG00000119508 ENSG00000036672 ENSG00000292354 ENSG00000188229 ENSG00000099860 ENSG00000087586 ENSG00000124875 ENSG00000148344 ENSG00000145386 ENSG00000124212 ENSG00000111348 ENSG00000048740 ENSG00000112312 ENSG00000159167 ENSG00000147408 ENSG00000172716 ENSG00000009950 ENSG00000148773 ENSG00000127954 ENSG00000166106 ENSG00000146678 ENSG00000136869 ENSG00000137267 ENSG00000113070 ENSG00000131095 ENSG00000163661 ENSG00000073756 ENSG00000132170 ENSG00000180447 ENSG00000115884 ENSG00000122952 ENSG00000170458 ENSG00000124882 ENSG00000138615 PMC368431__F1 Sample view of a VisAnt application ENSG00000197601 PMC8894694__F4 Lipid rafts as viral entry routes and immune platforms: A double-edged sword in SARS-CoV-2 infection? ENSG00000130234 ENSG00000186716 ENSG00000172936 PMC6423593__F6 Pathview graph for the Kyoto Encyclopedia of Genes and Genomes term ‘calcium signaling pathway’ allows the visualization of the differentially expressed genes involved in this signaling pathway ENSG00000182533 ENSG00000156026 ENSG00000186716 PMC9022973__F2 Gal-8 on cytokine expression and secretion ENSG00000011028 ENSG00000125538 ENSG00000198793 ENSG00000026508 PMC7565128__F1 Hh pathway (inactive state and active state) and the crosstalk between Hh and EGFR pathways ENSG00000138798 ENSG00000177606 ENSG00000164690 ENSG00000146648 PMC7565128__F2 Crosstalk between Hh signaling pathway and PI3K/AKT/mTOR pathway, Wnt/Beta-catenin pathway, Notch pathway ENSG00000281324 ENSG00000125398 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000177606 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC6171019__F1 Signaling pathway with PLD1 participation was activated in LNCaP cells in the androgen-free environment ENSG00000002330 ENSG00000198793 ENSG00000173599 PMC3242363__F5 The mechanism of late PC ENSG00000115415 ENSG00000291971 ENSG00000168610 PMC3741132__F1 Application of Artificial Neural Networks to Investigate One-Carbon Metabolism in Alzheimer’s Disease and Healthy Matched Individuals ENSG00000124275 ENSG00000035928 ENSG00000116984 PMC10300409__GA1 Oncolytic therapy with recombinant vaccinia viruses targeting the interleukin-15 pathway elicits a synergistic response ENSG00000164136 PMC8235796__F1 Expression of Wnt and TGF-Beta Pathway Components during Whole-Body Regeneration from Cell Aggregates in Demosponge Halisarca dujardinii ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000133116 ENSG00000168036 PMC6854717__F6 Mechanism scheme uncovers that CRISPR/Cas9-mediated knockout of NSD1 promotes H3K27me3 methylation and inhibits Wnt10b transcription, thereby suppressing activation of the Wnt/Beta-catenin signaling pathway ENSG00000169884 ENSG00000168036 PMC7456893__F1 Canonical and the non-canonical Wnt signaling pathways ENSG00000162552 ENSG00000154342 ENSG00000154764 ENSG00000134982 ENSG00000169884 ENSG00000026508 ENSG00000168036 ENSG00000111186 ENSG00000134245 ENSG00000277641 ENSG00000125084 PMC7978298__F3 ROS induce cell death, mainly including apoptosis, necroptosis and ferroptosis ENSG00000168003 ENSG00000132906 ENSG00000151012 ENSG00000102871 ENSG00000100504 ENSG00000078237 ENSG00000168040 ENSG00000026103 PMC7978298__F1 Primary generation and elimination mechanisms of intracellular ROS ENSG00000151376 ENSG00000065833 ENSG00000182511 ENSG00000100714 ENSG00000086991 ENSG00000172005 ENSG00000074771 ENSG00000188747 ENSG00000105227 PMC7961018__F1 Canonical TGFB signaling regulates the relationship between prenatal maternal depression and amygdala development in early life PMC3001241__F1 MHC class II antigen processing pathways containing P PMC3001241__F2 Toll-like receptor signaling pathways containing P ENSG00000239732 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000064012 ENSG00000174611 ENSG00000164342 PMC9659230__F5A Reprograming of Gene Expression of Key Inflammatory Signaling Pathways in Human Peripheral Blood Mononuclear Cells by Soybean Lectin and Resveratrol ENSG00000213928 ENSG00000111537 ENSG00000125347 PMC9159819__F1 Neurobiological Links between Stress, Brain Injury, and Disease ENSG00000128272 ENSG00000144895 ENSG00000198793 PMC7418744__F1 Pictographic representation showing the potential role of statins in COVID-19 infection ENSG00000111537 ENSG00000122194 PMC4276888__F7 Schematic of proposed TXNIP/miR-200/Zeb1/E-cadherin signaling pathway ENSG00000265972 PMC7560959__F7 Proposed metabolic pathway illustrating OTA nephrotoxicity ENSG00000079999 PMC4243516__F1 Signaling partners of the p75NTR ENSG00000169783 ENSG00000175104 ENSG00000237834 PMC9125939__F8 NOX4 blockade suppresses titanium nanoparticle-induced bone destruction via activation of the Nrf2 signaling pathway ENSG00000086991 ENSG00000131196 PMC9355645__F7 Transcriptome and Metabolome Analyses Reveal Differences in Terpenoid and Flavonoid Biosynthesis in Cryptomeria fortunei Needles Across Different Seasons ENSG00000108582 ENSG00000110921 ENSG00000113161 ENSG00000015285 ENSG00000117682 PMC3159106__F2 TLR-mediated myeloid differentiation primary response gene 88 (MyD88)-dependent and TIR domain containing adaptor inducing interferon (IFN)B (TRIF)-dependent signaling pathways ENSG00000174125 ENSG00000183735 ENSG00000226275 ENSG00000170458 ENSG00000187554 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC3492958__F1 Distinct roles for AlphaB hydrolase domain 5 (ABHD5/CGI-58) and adipose triglyceride lipase (ATGL/PNPLA2) in lipid metabolism and signaling ENSG00000166819 ENSG00000140992 ENSG00000169047 ENSG00000173599 ENSG00000198670 PMC7834960__F3 These pathways play an important role in cell growth, proliferation, and homeostasis, thus, a mutation in anyone may cause cancer cell survival, division and metastasis ENSG00000106571 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000164690 ENSG00000128602 ENSG00000146648 PMC7834960__F4 Emerging trends in colorectal cancer: Dysregulated signaling pathways (Review) ENSG00000168040 ENSG00000131023 ENSG00000079999 PMC5557756__F7 Schematic of a mechanosensitive pathway whereby low magnitude SS acts through the ER stress response pathways XBP1 and eIF2A to promote IRF-1-mediated VCAM-1 expression and VLA-4-dependent monocyte adhesion ENSG00000144895 ENSG00000100219 ENSG00000162692 ENSG00000125347 PMC8576642__F7 Berberine attenuates atherosclerotic lesions and hepatic steatosis in ApoE-/- mice by down-regulating PCSK9 via ERK1/2 pathway ENSG00000125538 ENSG00000198793 ENSG00000086991 ENSG00000162692 ENSG00000096717 ENSG00000169174 PMC6945027__F5 Model for the regulation of the Hippo pathway by Vgll3 and Akap11 ENSG00000146376 ENSG00000023516 ENSG00000197905 ENSG00000206538 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC3159106__F3 TLRs crosstalk with the phosphoinositide 3-kinase (PI3K) signaling pathway ENSG00000198793 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000175104 PMC1636849__F8 Schematic summary of the signaling pathway leading to Nanog repression ENSG00000179059 ENSG00000141448 PMC4582187__F7 Model describing the modulation of MLP quality control at the proteasome by BAG6 and SGTA ENSG00000047410 ENSG00000104969 ENSG00000204463 ENSG00000102178 PMC4101967__F2 Interference with type I IFN-activated JAK/STAT signaling pathway and antiviral ISGs ENSG00000213928 ENSG00000187608 ENSG00000105397 ENSG00000114030 ENSG00000142166 PMC8710575__F1 Gut Dysbiosis and Intestinal Barrier Dysfunction: Potential Explanation for Early-Onset Colorectal Cancer ENSG00000171759 ENSG00000168036 ENSG00000168610 PMC5474518__F75 Angiotensin-II-induced Muscle Wasting is Mediated by 25-Hydroxycholesterol via GSK3B Signaling Pathway ENSG00000002330 ENSG00000138135 PMC8724616__F1 IGF1–PI3K-induced physiological cardiac hypertrophy: Implications for new heart failure therapies, biomarkers, and predicting cardiotoxicity ENSG00000140443 PMC8904924__F1 Updated Review on Ozone Therapy in Pain Medicine ENSG00000181019 ENSG00000113520 ENSG00000104432 ENSG00000079999 PMC6757020__F10 Illustration of pathway signalling where phosphorylation signalling PTMs have been sequenced and annotated in melanoma tumours from patients ENSG00000135446 ENSG00000198793 ENSG00000135903 ENSG00000171791 ENSG00000100146 PMC5671526__F8 Schematic representations of potential mechanisms of PEBP1 in enhancing inflammatory response and neuron apoptosis after I/R injury ENSG00000125538 PMC4423995__F1 Netrin-1 – DCC Signaling Systems and Age-Related Macular Degeneration ENSG00000065320 ENSG00000198626 PMC4282344__F1 Pathways implicated in Alzheimer's disease (AD) ENSG00000142192 ENSG00000203710 ENSG00000120885 ENSG00000073712 ENSG00000073921 ENSG00000149187 ENSG00000140090 ENSG00000137642 ENSG00000112195 ENSG00000284816 ENSG00000281614 ENSG00000143801 ENSG00000078487 ENSG00000120899 ENSG00000087589 PMC6078181__F2 Pharmacological mechanism of roflumilast in the treatment of asthma–COPD overlap ENSG00000169245 ENSG00000134982 ENSG00000125538 ENSG00000001626 ENSG00000277943 PMC4254744__F6 HMGB1 Promotes a p38MAPK Associated Non-Infectious Inflammatory Response Pathway in Human Fetal Membranes ENSG00000189403 ENSG00000172936 ENSG00000136869 PMC2787631__F7 Working model of PKA’s role in trastuzumab resistance ENSG00000005882 ENSG00000146648 PMC4760904__F6 Agrin and LRP4 are central to a chondrogenic signalling network ENSG00000139219 ENSG00000281324 ENSG00000125398 ENSG00000162337 ENSG00000134569 ENSG00000157766 PMC5086377__F1 TNF signaling pathway anomalies through antiapoptotic signaling by TNFR1 helped by upregulation of TRAF1 and inhibition of proapoptotic TNFR1 signaling by BIRC1/3 caspase inactivation ENSG00000138378 ENSG00000102871 ENSG00000136997 ENSG00000168040 ENSG00000127191 PMC6263441__F1 Comparative Genomics Supports Sex and Meiosis in Diverse Amoebozoa ENSG00000108055 ENSG00000057468 ENSG00000285007 ENSG00000164754 ENSG00000100206 ENSG00000054796 ENSG00000095002 PMC6452301__F4 Interplay of well-known germline and somatic mutations in atherogenesis ENSG00000130164 ENSG00000134982 ENSG00000125538 ENSG00000132855 ENSG00000134243 ENSG00000169174 PMC8645963__F1 Insight Into Nicotinamide Adenine Dinucleotide Homeostasis as a Targetable Metabolic Pathway in Colorectal Cancer ENSG00000151376 ENSG00000065833 ENSG00000008130 ENSG00000082212 PMC8645963__F2 Insight Into Nicotinamide Adenine Dinucleotide Homeostasis as a Targetable Metabolic Pathway in Colorectal Cancer ENSG00000151376 ENSG00000065833 ENSG00000008130 ENSG00000082212 PMC7500474__F1 11-Oxygenated C19 Steroids Do Not Distinguish the Hyperandrogenic Phenotype of PCOS Daughters from Girls with Obesity ENSG00000203859 ENSG00000176387 PMC5825090__F1 The folate pathway in pancreatic cancer risk ENSG00000228716 ENSG00000100714 ENSG00000173599 ENSG00000124275 ENSG00000116761 ENSG00000016391 ENSG00000116984 ENSG00000133027 PMC4972972__F1 Dual regulation of GSK3 by the PI3K/Akt/GSK3 pathway and PLIN2 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000169047 ENSG00000168036 PMC2757186__F9 Working model for the biochemical cascade leading to the AR PMC3032584__F1 NF-kappaB, a mediator for lung carcinogenesis and a target for lung cancer prevention and therapy ENSG00000104856 ENSG00000102871 ENSG00000127191 PMC6628025__F1 Fibroblast growth factor receptors (FGFRs) are highly conserved transmembrane receptors consisting of three extracellular immunoglobulin-like (Ig-like) domains, a transmembrane helical region, and a cytoplasmic region with kinase activity PMC6707858__F1 Role of the Endolysosomal System in Parkinson’s disease ENSG00000129003 ENSG00000158828 ENSG00000069329 PMC6959064__F2 Calreticulin-mediated LMP1 signaling network that promotes EMT in NP69 cells ENSG00000182718 ENSG00000160789 ENSG00000111057 ENSG00000187531 ENSG00000102317 ENSG00000162433 ENSG00000150093 ENSG00000164305 ENSG00000171345 ENSG00000104368 ENSG00000186081 ENSG00000158290 ENSG00000185591 ENSG00000001626 ENSG00000062485 PMC4005015__F9A DIETARY HYPERGLYCEMIA, GLYCEMIC INDEX AND METABOLIC RETINAL DISEASES ENSG00000134086 PMC7521521__F1 Cullin-RING E3 ligases (CRLs) and the NEDD8 conjugation pathway ENSG00000100387 ENSG00000174989 ENSG00000113558 ENSG00000167986 PMC6613878__F1 Therapeutic strategies targeting NAMPT against stroke ENSG00000143799 ENSG00000105835 ENSG00000123572 ENSG00000198793 ENSG00000278488 ENSG00000077463 ENSG00000096717 ENSG00000283100 PMC8699548__F2 Multicellular Effects of STAT3 in Non-small Cell Lung Cancer: Mechanistic Insights and Therapeutic Opportunities ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC7281185__F1 Impact of nitric oxide (NO) in senescence-mediated signaling pathways ENSG00000149311 ENSG00000108691 ENSG00000107562 ENSG00000115415 ENSG00000163739 PMC6131595__F5 Metabolic reprogramming in cancer cells ENSG00000078237 PMC9587781__F3 Complement Pathway: New Insights into Immunometabolic Signaling in Diabetic Kidney Disease ENSG00000162711 ENSG00000125538 PMC3524013__F3 Full network comparison of the original canonical pathway and the inferred cell-type-specific pathway ENSG00000115008 ENSG00000163235 ENSG00000169047 ENSG00000095015 ENSG00000127191 ENSG00000135341 ENSG00000146648 PMC9587781__F1 Complement Pathway: New Insights into Immunometabolic Signaling in Diabetic Kidney Disease ENSG00000039537 ENSG00000113600 ENSG00000197405 ENSG00000166278 PMC11099588__F1 Biological functions of Amot family proteins and associated signal transduction pathways ENSG00000126016 ENSG00000069869 ENSG00000198793 ENSG00000166025 ENSG00000164327 ENSG00000288353 ENSG00000120913 ENSG00000132849 ENSG00000114019 ENSG00000072415 PMC7851309__F8 Neuroprotective Activities of Long-Acting Granulocyte–Macrophage Colony-Stimulating Factor (mPDM608) in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Intoxicated Mice ENSG00000119508 ENSG00000115590 ENSG00000162924 ENSG00000049768 ENSG00000125347 ENSG00000069667 ENSG00000132170 ENSG00000176953 ENSG00000177426 ENSG00000183134 ENSG00000162676 ENSG00000178573 ENSG00000112486 PMC9587781__F2 Complement Pathway: New Insights into Immunometabolic Signaling in Diabetic Kidney Disease ENSG00000197405 PMC6072627__F2 Intracellular activation of innate immune signaling by hyaluronan matrix ENSG00000187554 ENSG00000026508 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC6566080__F9 Cytokine-cytokine receptor interaction signaling pathway map in the male group ENSG00000110944 ENSG00000107562 ENSG00000183625 ENSG00000124875 ENSG00000121807 ENSG00000121966 ENSG00000127743 ENSG00000117400 ENSG00000125538 ENSG00000163734 ENSG00000113520 ENSG00000128342 ENSG00000056736 ENSG00000104432 ENSG00000112486 ENSG00000115008 ENSG00000099985 ENSG00000242689 ENSG00000115590 ENSG00000145777 ENSG00000277943 ENSG00000162594 ENSG00000169245 ENSG00000186810 ENSG00000102245 ENSG00000137077 ENSG00000164136 ENSG00000126353 ENSG00000115009 ENSG00000168685 PMC8630747__F5 Circadian Clock Protein BMAL1 Acts as a Metabolic Sensor In Macrophages to Control the Production of Pro IL-1B ENSG00000168610 PMC7954711__F1 The B6 vitamers pyridoxal (PL), pyridoxine (PN), pyridoxamine (PM) and the respective phosphate esters pyridoxal-5′-phosphate (PLP), pyridoxine-5′-phosphate (PNP) and pyridoxamine-5′-phosphate (PMP) ENSG00000291814 ENSG00000139515 ENSG00000173599 PMC6566080__F8 Hematopoietic cell lineage signaling pathway in the male and female groups ENSG00000177455 ENSG00000164151 ENSG00000163624 ENSG00000170458 ENSG00000104894 ENSG00000272398 ENSG00000158825 ENSG00000164399 ENSG00000026508 ENSG00000174059 PMC8304501__F1 Oncolytic Virus-Induced Autophagy in Glioblastoma ENSG00000198382 ENSG00000198793 PMC8745434__F1 Hedgehog Signaling Pathway in Idiopathic Pulmonary Fibrosis: Resurrection Time ENSG00000180447 ENSG00000106571 ENSG00000164161 ENSG00000134057 ENSG00000166813 ENSG00000154309 ENSG00000128602 PMC129737__F5 Model for repair of camptothecin-induced replicative damage ENSG00000113456 ENSG00000042088 PMC4283622__F1 Capecitabine activation and subsequent 5-FU activation, action, transport and catabolism ENSG00000188641 ENSG00000172831 ENSG00000167325 ENSG00000171848 ENSG00000158825 ENSG00000147647 ENSG00000167900 ENSG00000143179 PMC3548426__F1 Telomere syndromes ENSG00000166340 ENSG00000178971 ENSG00000145912 ENSG00000257949 ENSG00000109534 ENSG00000291996 ENSG00000164362 ENSG00000107960 ENSG00000128513 PMC5342330__F9 Novel function of MDA-9/Syntenin (SDCBP) as a regulator of survival and stemness in glioma stem cells ENSG00000148400 ENSG00000291971 ENSG00000133961 ENSG00000168610 ENSG00000072201 ENSG00000140443 PMC6855070__F2 Molecular pathway signaling of angiogenesis-induced epithelial-mesenchymal transition in hepatocellular carcinoma ENSG00000019991 ENSG00000105329 ENSG00000112715 PMC3137145__F3 Cigarette smoke exposure induces autophagy and apoptosis ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC2643977__F4 Proposed integrated model for local water transport inhibition by activation of P2Y2 and adenosine A1 receptors (A1R) in inner medullary collecting duct principal cell ENSG00000167580 ENSG00000171885 PMC11647666__F11 Reduction reactions dominate the interactions between Mg alloys and cells: Understanding the mechanisms ENSG00000104415 ENSG00000092439 ENSG00000125398 ENSG00000169071 ENSG00000134982 ENSG00000198793 ENSG00000175592 ENSG00000185483 ENSG00000168036 ENSG00000146648 PMC5650456__F1 Overcoming resistance to targeted therapy with immunotherapy and combination therapy for metastatic melanoma ENSG00000157404 ENSG00000089692 ENSG00000157764 ENSG00000163235 ENSG00000138798 ENSG00000171791 ENSG00000146648 PMC2716541__F6 Apoptosis of CD4+CD25high T Cells in Type 1 Diabetes May Be Partially Mediated by IL-2 Deprivation ENSG00000120889 ENSG00000099860 ENSG00000116717 ENSG00000171791 ENSG00000118971 ENSG00000080546 ENSG00000026103 PMC2881756__F7 Model illustrating the role of WDR3 in mediating cross-talk between ribosome biogenesis and p53-mediated cell cycle regulation PMC3299554__F1 Diagrammatic representation of the Akt signaling pathway.Notes: Activation of receptor tyrosine kinase (RTK) by growth factor binding activates PIK3 ENSG00000002330 ENSG00000198793 PMC4829553__F4 Genes positively and negatively connected to the expression of Egfr in the mouse liver ENSG00000099901 ENSG00000171956 ENSG00000165119 ENSG00000090402 ENSG00000106803 ENSG00000269335 ENSG00000205250 ENSG00000146648 PMC4059147__F5 Scheme for GAG biosynthesis (chondroitin/dermatan and heparan sulfate synthesis and keratan sulfate synthesis pathway) (A) and degradation (B) ENSG00000106302 ENSG00000176022 ENSG00000181523 ENSG00000272916 ENSG00000213614 ENSG00000173083 ENSG00000068001 ENSG00000049860 ENSG00000169919 ENSG00000136213 ENSG00000151348 ENSG00000111962 ENSG00000138604 ENSG00000136720 ENSG00000147119 ENSG00000169105 ENSG00000186792 ENSG00000123989 ENSG00000127415 PMC9610022__F3 High-Fat Diet and Female Fertility across Lifespan: A Comparative Lesson from Mammal Models ENSG00000104899 ENSG00000198793 PMC4548049__F2 Inborn errors underlying herpes simplex encephalitis: From TLR3 to IRF3 ENSG00000183735 ENSG00000164430 ENSG00000131323 ENSG00000164342 PMC9106715__F8 Working model displays the mechanism of which RP1-59D14.5-modulated PCa tumorigenesis and progression ENSG00000197905 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC5391049__F1 Wnt Signaling and Colorectal Cancer ENSG00000116729 ENSG00000134982 ENSG00000133067 ENSG00000107854 ENSG00000136997 ENSG00000102312 ENSG00000168036 ENSG00000108375 ENSG00000168646 PMC4829553__F3 Sex Difference of Egfr Expression and Molecular Pathway in the Liver: Impact on Drug Design and Cancer Treatments? ENSG00000099901 ENSG00000171956 ENSG00000165119 ENSG00000090402 ENSG00000106803 ENSG00000132432 ENSG00000269335 ENSG00000205250 ENSG00000004455 ENSG00000157800 ENSG00000153982 ENSG00000080618 ENSG00000152767 ENSG00000134285 ENSG00000083807 ENSG00000113790 ENSG00000146648 ENSG00000156471 ENSG00000124783 PMC2538513__F2 The involvement of death receptor pathway (right half) and mitochondrial pathway mediated (left half) apoptosis in nurse cell formation ENSG00000102871 ENSG00000120868 ENSG00000168040 ENSG00000127191 PMC2538513__F4 Schematic illustration of the involvement of c-Ski and TGFB signaling pathway in nurse cell formation ENSG00000157933 PMC3086210__F9 NH2-terminal Propeptide of Type I Procollagen Acts Intracellularly to Modulate Cell Function PMC10532419__F3 LOXL2 in Cancer: A Two-Decade Perspective ENSG00000019995 ENSG00000166326 ENSG00000169554 ENSG00000134013 ENSG00000172889 ENSG00000185591 ENSG00000107077 PMC10532419__F4 LOXL2 in Cancer: A Two-Decade Perspective ENSG00000134013 ENSG00000150630 PMC9229135__F2 Clinical Escherichia coli: From Biofilm Formation to New Antibiofilm Strategies ENSG00000151702 ENSG00000182263 PMC8113272__F2 Genomic network analysis showing the central role of genes related with cell cycle pathway ENSG00000100234 ENSG00000171855 ENSG00000163939 ENSG00000178951 ENSG00000281324 ENSG00000181163 ENSG00000169862 ENSG00000164251 ENSG00000181104 ENSG00000101115 ENSG00000110931 ENSG00000135111 ENSG00000112118 ENSG00000101266 ENSG00000137845 ENSG00000175054 ENSG00000159216 ENSG00000171456 ENSG00000125398 ENSG00000122691 ENSG00000136997 ENSG00000137203 ENSG00000115138 ENSG00000170430 ENSG00000087842 ENSG00000104365 ENSG00000169554 ENSG00000089225 ENSG00000065978 ENSG00000124216 ENSG00000135446 ENSG00000026508 ENSG00000128602 PMC6306679__F4 Mitochondrial NAD+/NADH Redox State and Diabetic Cardiomyopathy ENSG00000105835 ENSG00000157064 ENSG00000112992 PMC8192371__F1 Beyond Microsatellite Instability: Evolving Strategies Integrating Immunotherapy for Microsatellite Stable Colorectal Cancer ENSG00000089692 ENSG00000136869 ENSG00000146648 PMC5562708__F7 IRS4 interferes with BMP signal transduction and functions as a novel regulator of BMP signalling and myogenesis ENSG00000170365 ENSG00000198793 ENSG00000133124 ENSG00000125968 PMC5101720__F8 Pathway analysis using the KEGG Pathway database ENSG00000163902 ENSG00000198576 ENSG00000143839 ENSG00000291973 PMC5101720__F7 Pathway analysis using the KEGG Pathway database ENSG00000197713 ENSG00000198576 ENSG00000143839 ENSG00000291973 PMC3058357__F3 GRAIL and Otub1 regulation by the mTOR pathway controls naïve CD4 T cell proliferation ENSG00000198793 PMC6895440__F2 Several typical post-translational modifications of PGK1 ENSG00000140992 ENSG00000127445 ENSG00000171720 ENSG00000198793 ENSG00000146648 PMC11464892__F7 IL-17 signaling pathway in CD 138 + MM cells ENSG00000142192 ENSG00000149968 ENSG00000157625 ENSG00000100985 ENSG00000168040 ENSG00000155313 ENSG00000143556 ENSG00000163702 PMC6895440__F3 PGK1 involvement in drug resistance ENSG00000088305 ENSG00000175592 PMC8913496__F1 RhoG’s Role in T Cell Activation and Function ENSG00000167323 ENSG00000134982 ENSG00000293604 ENSG00000105639 ENSG00000109689 ENSG00000168685 PMC6594866__F2 Key cytokines and transcription factors involved in the regulation of megakaryocyte maturation ENSG00000151702 ENSG00000102145 ENSG00000117400 ENSG00000125538 ENSG00000179348 PMC8074291__F7 Pepsin Promotes Activation of Epidermal Growth Factor Receptor and Downstream Oncogenic Pathways, at Slightly Acidic and Neutral pH, in Exposed Hypopharyngeal Cells ENSG00000198793 ENSG00000171791 ENSG00000168610 ENSG00000146648 PMC3240668__F6 Fibronectin - c-Myc network ENSG00000134982 ENSG00000168036 ENSG00000112118 ENSG00000112715 ENSG00000174444 ENSG00000010671 ENSG00000125691 ENSG00000070444 ENSG00000169291 ENSG00000074800 ENSG00000008988 ENSG00000135776 ENSG00000174748 ENSG00000071082 ENSG00000197958 ENSG00000119655 ENSG00000088247 ENSG00000167967 ENSG00000169813 PMC8533551__F1 Participation of Selected Soluble BMP-2 and BMP-7 Bone Morphogenetic Proteins and Their Soluble Type I ALK-1 and Type II BMPR2 Receptors in Formation and Development of Endometriosis ENSG00000204217 PMC7490524__F1 Alternative splicing rewires Hippo signaling during chronic liver injury and HCC ENSG00000186575 ENSG00000076770 PMC3584681__F2 Pattern-recognition receptors (PRRs) and signaling pathways that lead to differentiation of antifungal T helper (Th) cells ENSG00000104856 ENSG00000162711 ENSG00000187796 ENSG00000125538 ENSG00000172005 ENSG00000132478 ENSG00000172936 PMC4488795__F2 Hepatic lipid homeostasis is regulated by LRP6 ENSG00000281324 ENSG00000130164 ENSG00000042832 ENSG00000170522 ENSG00000169174 ENSG00000026103 PMC3016145__F1 Intracellular and extracellular chromogranin/secretogranin actions ENSG00000171951 ENSG00000089199 PMC4783290__F7 Epithelial cell fate in the nephron tubule is mediated by the ETS transcription factors etv5a and etv4 during zebrafish kidney development ENSG00000171444 ENSG00000175832 ENSG00000062485 PMC6732626__F7 In the DP-treated cells, DP preferentially recognized and activated EGFR receptors on the cell surface ENSG00000198793 ENSG00000146648 PMC5742578__F1 Structure and function of ARNAX ENSG00000088888 ENSG00000127666 ENSG00000164342 PMC3472468__F4 Effects of sleep deprivation on the insulin signaling pathway ENSG00000120833 ENSG00000171105 ENSG00000182473 ENSG00000150907 ENSG00000198793 ENSG00000219607 ENSG00000135447 PMC7331746__F3 Essential functions of mitochondrial dynamics in immune cells ENSG00000177575 ENSG00000111537 ENSG00000116688 ENSG00000125347 PMC6296478__F1 Post-transcriptional regulation of cytokine expression and signaling ENSG00000101109 ENSG00000159216 ENSG00000020633 ENSG00000172936 ENSG00000185591 ENSG00000130159 ENSG00000175104 PMC7331746__F4 Essential functions of mitochondrial dynamics in immune cells ENSG00000100290 ENSG00000170458 ENSG00000116688 ENSG00000198793 ENSG00000285379 PMC9319897__F5 Plasma Oxylipins and Their Precursors Are Strongly Associated with COVID-19 Severity and with Immune Response Markers ENSG00000169245 ENSG00000150782 ENSG00000108691 ENSG00000125538 ENSG00000102970 ENSG00000104432 ENSG00000132693 PMC7331746__F2 Essential functions of mitochondrial dynamics in immune cells ENSG00000116688 ENSG00000125347 PMC4741699__F1 Functional signaling pathway analysis of lung adenocarcinomas identifies novel therapeutic targets for KRAS mutant tumors ENSG00000170365 ENSG00000169291 ENSG00000105397 ENSG00000149269 ENSG00000198793 ENSG00000120693 ENSG00000026508 ENSG00000146648 ENSG00000105723 PMC12138068__F2 Phosphorylation and collagen-related diseases ENSG00000134020 ENSG00000281324 ENSG00000162337 ENSG00000115415 ENSG00000134982 ENSG00000125538 ENSG00000168610 PMC11944037__F11 Biomarker-pathway-target network diagram of IPE anti-RA ENSG00000228716 ENSG00000148346 ENSG00000109743 ENSG00000291971 ENSG00000291814 ENSG00000073756 ENSG00000163631 PMC4301309__F1 Central role of NMPRTase (Nampt*) in the salvage pathway for NAD biosynthesis and related cellular functions ENSG00000105835 ENSG00000157064 ENSG00000173614 PMC12138068__F4 Ubiquitination, SUMOylation, methylation and collagen-related diseases ENSG00000163904 ENSG00000204977 ENSG00000126457 ENSG00000146648 PMC8424979__F5 Tetraploidization event shaped the Aquilaria sinensis genome and contributed to the ability of sesquiterpenes synthesis ENSG00000160752 ENSG00000197429 ENSG00000113161 ENSG00000167508 PMC8804219__F2 Emerging Mechanisms and Disease Implications of Ferroptosis: Potential Applications of Natural Products ENSG00000167772 ENSG00000135423 ENSG00000138449 ENSG00000151012 ENSG00000178573 ENSG00000072274 ENSG00000167996 ENSG00000132383 ENSG00000134531 PMC7509998__F1 Pathway activation of Notch signalling receptors and their downstream signalling molecules ENSG00000140564 ENSG00000184916 PMC9490047__F1 Current applications of adipose-derived mesenchymal stem cells in bone repair and regeneration: A review of cell experiments, animal models, and clinical trials ENSG00000134086 ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC2574011__F1 Store-operated Ca2+ entry in T cells ENSG00000213658 ENSG00000293604 ENSG00000049768 PMC5797066__F3 Decorin and downstream signaling cascades in tumor cells ENSG00000100234 ENSG00000198793 ENSG00000136997 ENSG00000112715 ENSG00000146648 ENSG00000198300 PMC10968131__F5 EFNA4, FGFR4, SLC3A2, and HNF1A are involved in signaling pathways that may promote carcinogenesis ENSG00000168003 ENSG00000187682 ENSG00000157764 ENSG00000135100 ENSG00000160867 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000171608 PMC8804219__F1 Emerging Mechanisms and Disease Implications of Ferroptosis: Potential Applications of Natural Products ENSG00000135423 ENSG00000151012 ENSG00000105329 ENSG00000118564 ENSG00000078668 ENSG00000197429 ENSG00000113161 ENSG00000136381 ENSG00000079999 ENSG00000168003 ENSG00000181019 ENSG00000115415 ENSG00000167468 ENSG00000111684 ENSG00000167996 ENSG00000115107 PMC6434238__F2 Network for abnormal sub-pathway ENSG00000111713 ENSG00000115904 ENSG00000119596 ENSG00000169885 ENSG00000105647 ENSG00000281877 ENSG00000234616 ENSG00000118971 ENSG00000006062 ENSG00000186298 ENSG00000188338 ENSG00000078304 ENSG00000221823 ENSG00000066468 ENSG00000103479 ENSG00000117020 ENSG00000123374 ENSG00000139687 ENSG00000140443 ENSG00000135447 PMC3275089__F1 Schematic overview of the ABeta-Cav1.2-ptau-autophagy pathway ENSG00000185933 ENSG00000142192 PMC3936506__F3 Cell Cycle Regulators Guide Mitochondrial Activity in Radiation-Induced Adaptive Response ENSG00000138385 PMC7578249__F4 Impaired monocytes function in ACLF ENSG00000153208 ENSG00000137033 ENSG00000136869 ENSG00000121807 PMC7098821__F1 Mitochondrial Quality Control in the Heart: New Drug Targets for Cardiovascular Disease ENSG00000105550 ENSG00000158828 ENSG00000130513 PMC4169465__F1 The Role of Iron in Prion Disease and Other Neurodegenerative Diseases ENSG00000115107 PMC9066069__F3 High‐fat diet (HFD)‐induced reprogramming of the hepatic clock and metabolic homeostasis ENSG00000105835 ENSG00000096717 PMC7656422__F1 Immune suppression of Tregs via trans-endocytosis of CD80/86 from APCs PMC7037210__F1 Main anticancer molecular mechanisms mediated by cannabinoid receptors’ activation “↑, upregulation” and “↓, downregulation” ENSG00000128272 ENSG00000002330 ENSG00000291971 ENSG00000198793 ENSG00000168036 PMC8227118__F7 Genome-Wide Differential Methylation Profiles from Two Terpene-Rich Medicinal Plant Extracts Administered in Osteoarthritis Rats ENSG00000177455 ENSG00000124102 ENSG00000115956 ENSG00000002330 ENSG00000102034 ENSG00000186716 ENSG00000198793 ENSG00000104894 PMC10917649__SF6 Mapping of the identified gene classes of MetaCyc PWYG-321 mycolate biosynthesis to the KEGG ko00061 fatty acid biosynthesis pathway ENSG00000182511 ENSG00000116353 ENSG00000145439 ENSG00000255154 ENSG00000213614 ENSG00000169710 ENSG00000026103 PMC8582545__F1 Disruption of Tumor Suppressors HNF4A/HNF1A Causes Tumorigenesis in Liver ENSG00000102871 ENSG00000127191 ENSG00000168610 PMC7350758__F1 Vital signaling pathways and important substrates for downstream regulation of USP4 ENSG00000087095 ENSG00000196591 ENSG00000168036 ENSG00000127191 ENSG00000196628 PMC11817781__F4 Top 10 genes and associated critical phenotypes network ENSG00000284099 ENSG00000104368 PMC12199322__S1 Bimetallic Ca/Zn Nanoagonist Remould the Immunosuppressive Hepatocellular Carcinoma Microenvironment Following Incomplete Microwave Ablation via Pyroptosis and the STING Signaling Pathway ENSG00000189403 ENSG00000168610 PMC5814137__F4 Heterocellular nutrient symbiosis in the tumor microenvironment.Tumor-associated stromal cell populations engage in cooperative metabolic processes with cancer cells in the tumor microenvironment ENSG00000178860 ENSG00000122966 ENSG00000167074 PMC5673281__F3 Bile acids as global regulators of hepatic nutrient metabolism ENSG00000063176 ENSG00000291971 ENSG00000146648 PMC2118421__F7 Proposed model of RasGRP1 in FcɛRI-mediated signaling ENSG00000010810 PMC5668920__F1 Fas apoptotic pathway ENSG00000198589 ENSG00000026103 PMC7327349__F1 Graph of the IL-17 signaling pathway in KEGG database ENSG00000148346 ENSG00000149968 ENSG00000117400 ENSG00000105656 ENSG00000100985 ENSG00000168040 ENSG00000122194 PMC3004266__F10 Active Cdk1/cyclin B1 complex on the extrinsic death pathway ENSG00000134057 ENSG00000168040 ENSG00000026103 PMC10546379__F7 SIK2 on Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000170145 ENSG00000040199 PMC6609682__F7 IFITM3 promotes bone metastasis of prostate cancer cells by mediating activation of the TGFB signaling pathway ENSG00000142089 PMC10217969__F5 Transcriptome and Metabolome Reveal Distinct Sugar Accumulation Pattern between PCNA and PCA Mature Persimmon Fruit ENSG00000118094 ENSG00000163754 ENSG00000026103 PMC11083682__F3 Influenza viral degradation of cellular proteins that do not directly regulate IFN signaling ENSG00000094631 ENSG00000112576 ENSG00000116663 ENSG00000160075 ENSG00000196591 ENSG00000115415 ENSG00000078747 ENSG00000160703 ENSG00000142089 ENSG00000001626 ENSG00000288325 ENSG00000140464 ENSG00000163517 ENSG00000155363 ENSG00000124177 PMC10546379__F4 SIK1 inhibits tumor cell EMT by suppressing Beta-catenin signaling pathway and the expression of Twist 1 ENSG00000138795 ENSG00000142178 ENSG00000168036 ENSG00000196628 PMC11083682__F2 Influenza viral degradation of cellular proteins involved in the interferon responses ENSG00000143799 ENSG00000159128 ENSG00000213928 ENSG00000174013 ENSG00000088305 ENSG00000185436 ENSG00000027697 ENSG00000142166 ENSG00000188554 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000175104 PMC2820418__F12 PRG5 signaling in axon growth and neurite retraction ENSG00000070831 ENSG00000198670 PMC7723774__F1 Preparation of the chitosan/sodium alginate (CA/SA) hydrogel simultaneously loaded with parathyroid hormone fragment PTH(1–34) and nano-hydroxyapatite for promoting cranial bone regeneration via the Notch signaling pathway ENSG00000152266 ENSG00000273529 ENSG00000114315 PMC12249179__F8 Correction: Ye et al. The Mechanisms of lncRNA-Mediated Multidrug Resistance and the Clinical Application Prospects of lncRNAs in Breast Cancer. Cancers 2022, 14, 2101 PMC8358831__F3 Emerging Perspectives on Leukemia Inhibitory Factor and its Receptor in Cancer ENSG00000109321 ENSG00000128342 ENSG00000150457 ENSG00000131023 PMC6120108__F2 The BDNF/ TrkB signalling in normal and glaucomatous conditions ENSG00000128272 ENSG00000144895 ENSG00000124181 PMC8495202__F2 Desmosomes as Signaling Hubs in the Regulation of Cell Behavior ENSG00000138798 ENSG00000175065 ENSG00000134757 ENSG00000081277 ENSG00000184363 ENSG00000134760 ENSG00000057294 ENSG00000146648 ENSG00000046604 PMC6120108__F3 Downstream consequences of neurotrophin signalling pathway affecting gene function and ER stress marker is possibly implicated in progression of RGCs axon damage in glaucoma ENSG00000123240 ENSG00000128272 ENSG00000150991 ENSG00000144895 ENSG00000100219 ENSG00000134987 ENSG00000143183 PMC4716813__F2 Angiotensin-(1-7): A Novel Peptide to Treat Hypertension and Nephropathy in Diabetes? ENSG00000130234 PMC8980962__F5 JAK/STAT: Why choose a classical or an alternative pathway when you can have both? ENSG00000100385 ENSG00000105639 ENSG00000168610 PMC8980962__F2 JAK/STAT: Why choose a classical or an alternative pathway when you can have both? ENSG00000162594 ENSG00000138378 ENSG00000105397 ENSG00000168610 PMC11591759__F1 Two possible options for the interaction of Notch signaling pathway targets (Hes1, Hey1) with Runx2 ENSG00000114315 PMC1847591__F1 Drugs that regulate hepatic bile acid and other organic solute uptake, synthesis, detoxification and secretion ENSG00000167910 PMC10244093__F9 Linc00662 m6A promotes the progression and metastasis of pancreatic cancer by activating focal adhesion through the GTF2B-ITGA1-FAK pathway ENSG00000137947 ENSG00000213949 ENSG00000291971 ENSG00000136231 PMC6849407__F8 Schematic diagram of the potential mechanisms for CDDO-Me–mediated Nrf2 activation in CHF ENSG00000119682 ENSG00000181019 ENSG00000079999 PMC8678517__F2 Novel Pathways for Targeting Tumor Angiogenesis in Metastatic Breast Cancer ENSG00000170365 ENSG00000120693 ENSG00000138071 ENSG00000163217 PMC10970410__F8 Transcriptional Regulatory Networks (TRNs) based on DE pcRNAs common to KLF4KD and MXD4KD cells, in association with lncRNAs ENSG00000069667 ENSG00000213949 ENSG00000156103 ENSG00000092036 ENSG00000285395 ENSG00000066027 ENSG00000114107 ENSG00000198108 ENSG00000154721 ENSG00000184148 ENSG00000177283 ENSG00000184304 ENSG00000164619 ENSG00000101333 ENSG00000172201 ENSG00000113645 ENSG00000170899 ENSG00000171903 ENSG00000160145 ENSG00000153976 ENSG00000008513 ENSG00000197903 ENSG00000168874 ENSG00000008394 ENSG00000117152 ENSG00000152402 ENSG00000100526 ENSG00000161888 ENSG00000163661 ENSG00000162654 ENSG00000150637 ENSG00000146197 ENSG00000110876 ENSG00000136167 ENSG00000170961 ENSG00000117650 ENSG00000140285 ENSG00000171914 ENSG00000164093 ENSG00000138316 ENSG00000119508 ENSG00000170558 ENSG00000105499 ENSG00000095739 ENSG00000111186 ENSG00000174125 ENSG00000203783 ENSG00000140416 ENSG00000177606 PMC4731439__F1 TNFAlpha-related signal transduction pathway participating in the differentiation of skin appendages ENSG00000140564 ENSG00000186197 ENSG00000135960 ENSG00000131323 ENSG00000083799 ENSG00000175104 PMC7591509__F4 Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis ENSG00000108839 ENSG00000226275 ENSG00000161905 ENSG00000148344 ENSG00000275565 PMC4731439__F2 Interaction of proteins involved in signal transduction via the TNFAlpha-related signal transduction pathway (based on http://string-db.org, simplified) ENSG00000140564 ENSG00000150991 ENSG00000083799 ENSG00000175104 PMC8146983__SF1 Toward an Understanding of the Structural and Mechanistic Aspects of Protein-Protein Interactions in 2-Oxoacid Dehydrogenase Complexes ENSG00000157426 ENSG00000105607 PMC11683013__F2 CGAS-STING pathway activation, Chinese medicine inhibits or activates cGAS-STING signaling pathway to treat various diseases ENSG00000183735 ENSG00000164430 PMC2971525__F1 DNA Damage Response (DDR) pathways in normal and malignant cells ENSG00000188486 ENSG00000175054 ENSG00000150907 ENSG00000123374 ENSG00000026103 PMC8835786__F3 SARS-CoV-2-Specific Immune Response and the Pathogenesis of COVID-19 ENSG00000183735 ENSG00000131323 PMC3823115__F3 Potential mechanism of the HGF/ c-Met signal pathway hallmarks in lung cancer ENSG00000019991 ENSG00000198793 ENSG00000146648 PMC3823115__F1 TGFa/EGFR signal pathway may directly or indirectly lead to c-Met, while HGF/c-Met does not affect the phosphorylation of EGFR ENSG00000019991 ENSG00000163235 ENSG00000146648 PMC6923165__F3 Time-dependent changes of gene expression of the KRAS signaling pathway after treatment of PDAC model cell lines differing by the KRAS mutation status with paclitaxel in vitro ENSG00000124102 ENSG00000140992 ENSG00000017797 ENSG00000157764 ENSG00000120899 ENSG00000149269 ENSG00000006451 ENSG00000198793 ENSG00000169032 ENSG00000121879 PMC7913947__F1 The kynurenine pathway PMC6328617__F1 CD44v6 engages in colorectal cancer progression ENSG00000087245 ENSG00000291971 ENSG00000026508 ENSG00000168036 ENSG00000100985 PMC3136091__F1 Canonical and non-canonical NFKB signalling pathways ENSG00000104856 ENSG00000173039 PMC6328617__F2 CD44v6 engages in colorectal cancer progression ENSG00000087245 ENSG00000107562 ENSG00000026508 PMC5521196__F5 Conditional deletion of Sox17 reveals complex effects on uterine adenogenesis and function ENSG00000138795 ENSG00000164736 ENSG00000168036 PMC3200485__F2 RGS14 at the interface of hippocampal signaling and synaptic plasticity ENSG00000164879 ENSG00000169220 ENSG00000177963 ENSG00000138798 PMC6308626__F2 General mechanism of the extracellular signal-regulated kinase (ERK) pathway and key downstream products important in cocaine addiction ENSG00000177606 PMC8584463__F7 Substrate Stiffness Drives Epithelial to Mesenchymal Transition and Proliferation through the NEAT1-Wnt/Beta-Catenin Pathway in Liver Cancer ENSG00000134982 ENSG00000026508 ENSG00000168036 ENSG00000112715 ENSG00000168646 PMC4791550__F2 Continuous time Bayesian networks identify Prdm1 as a negative regulator of TH17 cell differentiation in humans ENSG00000156127 ENSG00000114737 ENSG00000168610 PMC2094118__F1 The HIF1 pathway in normoxia (A) and hypoxia (B) ENSG00000134086 ENSG00000111653 PMC4811429__F6 Storage Temperature Alters the Expression of Differentiation-Related Genes in Cultured Oral Keratinocytes ENSG00000164161 ENSG00000141480 ENSG00000164690 PMC1572165__F3 Schematic drawing that shows the importance of cell-to-cell and cell-to-matrix-interactions in endothelial cell survival ENSG00000111537 ENSG00000002330 ENSG00000168036 PMC6404322__F1 Challenges of driving CD30-directed CAR-T cells to the clinic ENSG00000102962 ENSG00000102970 PMC11591759__F2 Tissue-specific effect of the Runx2 transcription factor and its associations with various signaling pathways and target genes ENSG00000100385 ENSG00000197971 ENSG00000158887 PMC11663918__F1 Changes in proteins induced in the cytosol of microglia activated by BzATP and lipopolysaccharide (LPS) ENSG00000162711 ENSG00000118503 ENSG00000172936 ENSG00000175104 PMC8465379__F4 An Updated Comprehensive Review on Vitamin A and Carotenoids in Breast Cancer: Mechanisms, Genetics, Assessment, Current Evidence, and Future Clinical Implications ENSG00000198793 ENSG00000146648 PMC7002996__F5 KEGG pathway analysis of the p53 signaling pathway regulated by PCA ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000136997 ENSG00000042286 ENSG00000112378 ENSG00000196470 ENSG00000164305 ENSG00000026103 PMC4038464__F3 Activating Transcription Factor 6 Is Necessary and Sufficient for Alcoholic Fatty Liver Disease ENSG00000274296 ENSG00000130957 ENSG00000143158 ENSG00000059804 ENSG00000108515 ENSG00000288174 ENSG00000169710 ENSG00000074800 ENSG00000173599 ENSG00000110435 ENSG00000164708 ENSG00000124253 ENSG00000136872 ENSG00000146701 ENSG00000159399 ENSG00000138400 ENSG00000060762 PMC10454035__F2 Hedgehog (Hh) signaling pathway, normal and with Gorlin syndrome ENSG00000106571 ENSG00000117425 ENSG00000128602 PMC7226803__F3 Subcellular distribution of FoxO1 driven by nutritive stimuli in white/beige adipocytes ENSG00000171105 PMC3423785__F2 Functional analysis of the top-scoring network of AE9a dysregulated genes ENSG00000027075 ENSG00000142192 ENSG00000070182 ENSG00000118263 ENSG00000197746 ENSG00000276644 ENSG00000196743 ENSG00000138386 ENSG00000116717 ENSG00000132182 ENSG00000137393 ENSG00000166886 ENSG00000109787 ENSG00000124762 ENSG00000283082 ENSG00000134057 ENSG00000134243 ENSG00000275565 ENSG00000138180 ENSG00000143995 PMC7397661__F3 Interrelated regulatory of CircRNA and EMT ENSG00000170558 ENSG00000168036 PMC2862093__F6 Glucagon-like Peptide-1 Receptor (GLP-1R) is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway ENSG00000124102 ENSG00000005882 ENSG00000169047 PMC4552880__F1 Evidence of Active Pro-Fibrotic Response in Blood of Patients with Cirrhosis ENSG00000135218 ENSG00000142798 ENSG00000058085 ENSG00000189056 ENSG00000115221 ENSG00000164171 ENSG00000196739 ENSG00000101680 ENSG00000169231 ENSG00000172037 ENSG00000139219 ENSG00000072571 ENSG00000171502 ENSG00000053747 ENSG00000105664 ENSG00000136457 ENSG00000041982 ENSG00000029559 ENSG00000186340 ENSG00000278316 ENSG00000113296 ENSG00000188157 ENSG00000203618 ENSG00000026508 PMC6328617__F3 CD44v6 engages in colorectal cancer progression ENSG00000019991 ENSG00000107562 ENSG00000138798 ENSG00000026508 ENSG00000168036 ENSG00000146648 ENSG00000121966 PMC6328617__F4 CD44v6 engages in colorectal cancer progression ENSG00000181019 ENSG00000167996 ENSG00000026508 ENSG00000079999 PMC4552880__F2 Evidence of Active Pro-Fibrotic Response in Blood of Patients with Cirrhosis ENSG00000170365 ENSG00000039537 ENSG00000111537 ENSG00000095739 ENSG00000100387 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000185591 ENSG00000137801 PMC3606754__F2 STRING analysis of the relationship between genes ENSG00000226275 ENSG00000149968 ENSG00000139287 ENSG00000128052 ENSG00000173599 ENSG00000276051 ENSG00000104918 ENSG00000281879 ENSG00000112715 ENSG00000204520 ENSG00000132693 PMC3606754__F3 NF-AT signaling and leukocyte interactions have been enriched by GeneGo ENSG00000291603 ENSG00000213658 ENSG00000183625 ENSG00000186716 ENSG00000113520 ENSG00000131724 ENSG00000113263 PMC8165262__F1 Interleukin-27 and Its Diverse Effects on Bacterial Infections ENSG00000105397 ENSG00000105246 PMC3924248__F1 Contribution of MTHFR, MTR and MTHFD1 in the folate metabolic pathway ENSG00000100714 ENSG00000205221 ENSG00000116984 PMC4315992__F8 Signaling pathways for PDGF-induced proliferation in PSCs ENSG00000115415 ENSG00000291971 ENSG00000168610 PMC3192752__F5 Enteric Microbiome Metabolites Correlate with Response to Simvastatin Treatment ENSG00000276559 ENSG00000167910 ENSG00000180432 PMC11450209__F3 Exploring kinase-substrate interactions of proteins using KiNet ENSG00000171105 ENSG00000002330 ENSG00000157764 ENSG00000291971 ENSG00000169047 ENSG00000158828 ENSG00000141068 ENSG00000067900 ENSG00000281877 ENSG00000169032 ENSG00000135341 ENSG00000132356 ENSG00000196396 ENSG00000131023 ENSG00000117020 ENSG00000149269 ENSG00000136997 ENSG00000118515 ENSG00000137843 ENSG00000112742 ENSG00000146648 ENSG00000101210 ENSG00000155090 PMC3944239__F8 Working model ENSG00000167513 PMC7180799__F6 Proposed signaling pathways for the protective effect of LPA against simvastatin-induced cytotoxicity in L6 cells ENSG00000002330 ENSG00000198793 ENSG00000198670 ENSG00000171791 PMC9691847__F6 Baihu renshen decoction ameliorates type 2 diabetes mellitus in rats through affecting gut microbiota enhancing gut permeability and inhibiting TLR4/NFKB-mediated inflammatory response ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC3337844__F1 Autophagic proteins ENSG00000168040 ENSG00000026103 PMC8820459__F1 p38MAPK Signaling Pathway in Osteoarthritis: Pathological and Therapeutic Aspects PMC9458461__F6 Nuclear DNA damage response by mitochondrial morphofunctional pathway ENSG00000149311 ENSG00000012048 ENSG00000116688 ENSG00000171109 PMC7791134__F3 Distinct transcriptional signature of antidepressant response in hippocampal dentate gyrus granule cells ENSG00000178999 ENSG00000072571 ENSG00000089685 ENSG00000111837 ENSG00000170893 ENSG00000115353 ENSG00000108821 ENSG00000181585 ENSG00000149451 ENSG00000171320 ENSG00000277909 ENSG00000114346 ENSG00000174417 ENSG00000164694 ENSG00000184661 ENSG00000128655 ENSG00000174460 ENSG00000188133 ENSG00000143228 ENSG00000186871 ENSG00000138160 ENSG00000169836 ENSG00000134057 ENSG00000156970 ENSG00000171848 ENSG00000138180 PMC6137129__F8 Visualization of KEGG IL17 signaling pathway genes differentially perturbed (FDR < 0.05) in rat muscle infected with A ENSG00000159921 ENSG00000148346 ENSG00000105656 ENSG00000157625 ENSG00000128342 ENSG00000168040 ENSG00000175104 ENSG00000127191 ENSG00000152430 PMC6122050__F1 Tyrosine metabolic pathway – highlighting the site of the enzyme defect observed in alkaptonuria and type 1 hereditary tyrosinaemia and the site of action of nitisinone ENSG00000123454 ENSG00000141744 ENSG00000170893 PMC6090502__F9 Model for NG2 ICD-mediated intracellular signaling in OPCs ENSG00000198793 ENSG00000173599 ENSG00000284161 ENSG00000167658 PMC11079285__F3 TREM2 mediated immunosuppression and regulation of cancer progression ENSG00000168036 PMC6587274__F5 Summary of STAT3-FOXL2 signaling function in HeLa cell growth and apoptosis ENSG00000109163 ENSG00000168610 PMC7792759__F3 TGFB signalling pathway in breast cancer cells ENSG00000260027 PMC5043614__F1 Molecular subclassification of triple-negative breast cancer (TNBC) based on gene expression profiling ENSG00000012048 ENSG00000070831 ENSG00000291971 ENSG00000198793 PMC5043614__F2 Links between altered glucose and phosphatidylcholine metabolism in breast cancer ENSG00000198793 ENSG00000146648 ENSG00000026103 PMC11450209__F4 Exploring kinase-substrate interactions in functional contexts, such as pathways and shared domains using KiNet ENSG00000094631 ENSG00000228716 ENSG00000178999 ENSG00000291971 ENSG00000196591 ENSG00000101266 ENSG00000135341 ENSG00000108840 ENSG00000171720 ENSG00000129167 ENSG00000089022 ENSG00000184304 ENSG00000162889 ENSG00000152495 ENSG00000064393 ENSG00000150787 ENSG00000132356 ENSG00000177189 ENSG00000148660 ENSG00000147099 ENSG00000162409 ENSG00000139287 ENSG00000061273 ENSG00000185532 ENSG00000170145 ENSG00000171759 ENSG00000048052 ENSG00000100784 ENSG00000123143 ENSG00000115825 ENSG00000146648 ENSG00000145349 ENSG00000116096 ENSG00000130669 ENSG00000105287 PMC5670149__F1 Wnt/Beta-Catenin Signaling ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11079285__F2 TREM2, as an oncogene, promotes the progression of PTC, GC, PRAD, RCC, EAC, and BCC by activating the PI3K/Akt, NFKB, and JAK/STAT3 signaling pathways, respectively ENSG00000145321 ENSG00000168610 PMC4516462__F2 Transcriptional modifications of DNA repair by UPS in response to cellular stressing conditions ENSG00000012048 ENSG00000105486 ENSG00000177084 PMC1896004__F4 Signaling pathways downstream of the Toll/TLRs ENSG00000172936 ENSG00000130159 ENSG00000175104 PMC4516462__F3 Transcriptional activation of DNA repair mediated by UPS-dependent pathways ENSG00000012048 ENSG00000134574 ENSG00000132646 ENSG00000170430 ENSG00000051180 ENSG00000158169 ENSG00000095002 ENSG00000140464 ENSG00000122512 PMC9297598__F11 Mesenchymal stem cell-derived exosomes protect against liver fibrosis via delivering miR-148a to target KLF6/STAT3 pathway in macrophages ENSG00000178860 ENSG00000118520 ENSG00000168610 ENSG00000277943 PMC6374299__F2 MDSC-dependent promotion of PMN formation and evolution ENSG00000107562 ENSG00000143546 ENSG00000189403 ENSG00000136869 ENSG00000118520 ENSG00000100985 ENSG00000121966 PMC8395144__F1 An Update on the Role of Nrf2 in Respiratory Disease: Molecular Mechanisms and Therapeutic Approaches ENSG00000181019 ENSG00000023909 ENSG00000079999 PMC9273597__F1 STING cg16983159 methylation: a key factor for glioblastoma immunosuppression ENSG00000169245 ENSG00000164430 PMC7961553__F8 AIM2 function in microglia as a negative regulator of EAE ENSG00000117020 ENSG00000164430 ENSG00000163568 PMC7374198__F4 General overview of the lipid metabolism in Malassezia, based on lipidomic and in silico genomic analysis presented in and ENSG00000083857 ENSG00000173599 ENSG00000026103 PMC4756744__F1 AVP-dependent signaling pathways in myogenic cells ENSG00000285109 PMC9280743__F7 Mechanism and therapeutic strategy of hepatic TM6SF2-deficient non-alcoholic fatty liver diseases via in vivo and in vitro experiments ENSG00000213996 ENSG00000169710 PMC7244374__F1 Vitamin A uptake, transport, and metabolism ENSG00000121207 ENSG00000138207 ENSG00000073060 PMC3590201__F2 Identification of Pathway Markers in Intracranial Aneurysm Using Genome-Wide Association Data from Two Different Populations ENSG00000049323 ENSG00000137834 ENSG00000111537 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000164093 PMC3590201__F3 Identification of Pathway Markers in Intracranial Aneurysm Using Genome-Wide Association Data from Two Different Populations ENSG00000156026 ENSG00000186716 PMC3523093__F1 Liver Full of JNK: Signaling in Regulation of Cell Function and Disease Pathogenesis, and Clinical Approaches ENSG00000002330 ENSG00000130522 ENSG00000138798 ENSG00000169047 PMC9271392__F5 Importance of Sclerostin as Bone-Muscle Mediator Crosstalk ENSG00000111049 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000062485 PMC9271392__F6 Importance of Sclerostin as Bone-Muscle Mediator Crosstalk ENSG00000111049 ENSG00000134982 ENSG00000168036 ENSG00000062485 PMC9271392__F3 Importance of Sclerostin as Bone-Muscle Mediator Crosstalk ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000062485 PMC6723230__F2 Representative miRNA-gene network interactions between the genes with an altered expression levels when comparing tumor to normal tissue and their respective miRNAs, generated using miRNet ENSG00000162552 ENSG00000105327 ENSG00000117425 ENSG00000175793 ENSG00000162512 ENSG00000171791 ENSG00000099194 ENSG00000118971 ENSG00000124762 ENSG00000115884 ENSG00000180447 ENSG00000106571 ENSG00000134574 ENSG00000164161 ENSG00000188157 ENSG00000171848 ENSG00000026508 ENSG00000112378 PMC12238274__F3 Possible mechanisms of ApoE4 in microglial immune activation ENSG00000162711 ENSG00000135218 ENSG00000204577 ENSG00000198793 ENSG00000086991 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000127191 ENSG00000115419 PMC4558214__F1 Soluble recombinant molecule consisting of the extracellular domains of CD80 linked to the Fc domain of Ig (soluble CD80 or CD80-Fc) has the potential to maintain and facilitate T cell activation through three independent mechanisms ENSG00000134982 ENSG00000163599 PMC4628649__F2 Proposed model of the role of TOX in innate lymphoid cell development ENSG00000165030 ENSG00000198846 ENSG00000168685 PMC12238274__F1 Possible mechanisms by which ApoE4 affects AB production and clearance ENSG00000142192 ENSG00000198793 ENSG00000119912 PMC11896656__F1 Interferon-driven Metabolic Reprogramming and Tumor Microenvironment Remodeling ENSG00000183735 ENSG00000159128 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000198793 ENSG00000163565 ENSG00000027697 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC12238274__F2 Possible mechanisms by which ApoE4 affects tau phosphorylation and clearance ENSG00000154001 PMC3382204__F5 Predicting Candidate Genes Based on Combined Network Topological Features: A Case Study in Coronary Artery Disease ENSG00000019991 ENSG00000157404 ENSG00000099985 ENSG00000119535 ENSG00000183625 ENSG00000139269 ENSG00000163083 ENSG00000108342 ENSG00000274736 ENSG00000111321 ENSG00000145777 ENSG00000103522 ENSG00000226275 ENSG00000135960 ENSG00000117400 ENSG00000163235 ENSG00000164400 ENSG00000128342 ENSG00000037280 ENSG00000162892 ENSG00000292332 ENSG00000112486 ENSG00000026103 PMC3073781__F6 Schematic overview of the MDM2 and p53 signalling pathway ENSG00000136997 PMC3382204__F6 Predicting Candidate Genes Based on Combined Network Topological Features: A Case Study in Coronary Artery Disease ENSG00000177455 ENSG00000135218 ENSG00000170458 ENSG00000104894 ENSG00000272398 ENSG00000164399 ENSG00000026508 ENSG00000010278 ENSG00000187266 ENSG00000174059 PMC3382204__F7 Predicting Candidate Genes Based on Combined Network Topological Features: A Case Study in Coronary Artery Disease ENSG00000039537 ENSG00000003436 ENSG00000113600 ENSG00000110799 ENSG00000181104 ENSG00000166278 ENSG00000115718 ENSG00000122194 ENSG00000178726 ENSG00000117322 ENSG00000185010 ENSG00000104368 ENSG00000184500 ENSG00000180210 ENSG00000126218 ENSG00000101981 ENSG00000117525 ENSG00000011422 ENSG00000175899 ENSG00000080618 ENSG00000198734 ENSG00000062485 PMC7988715__F2 EZH2 overexpression in prostate cancer ENSG00000157554 ENSG00000136997 ENSG00000184012 PMC5644641__F1 Mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK) pathway ENSG00000138798 ENSG00000146648 PMC11509156__F3 Metabolite Profiling of Macroalgae: Biosynthesis and Beneficial Biological Properties of Active Compounds ENSG00000145321 PMC11749514__F5 Role of the key gene set in the signaling pathway in PI3K-AKT ENSG00000177455 ENSG00000103479 ENSG00000213928 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000169047 ENSG00000104894 ENSG00000131095 PMC4381970__F3 Biological activities of TACI ENSG00000172936 ENSG00000136869 ENSG00000026103 PMC3763651__F1 Schematic presentation depicting the regulation of receptor signaling through G-proteins ENSG00000291971 ENSG00000168610 PMC4744895__F1 Schematic diagram of potential mild freezing shock signaling pathways in barley ENSG00000110395 ENSG00000173599 PMC6523340__F4 Simplified biosynthetic pathway of lignin and flavonols ENSG00000102977 ENSG00000084774 PMC3729625__F2 Cellular Metabolic and Autophagic Pathways: Traffic Control by Redox Signaling ENSG00000177169 ENSG00000152348 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC3729625__F3 Cellular Metabolic and Autophagic Pathways: Traffic Control by Redox Signaling ENSG00000078237 ENSG00000145782 PMC4577901__F3 Signaling network of genes that are strongly upregulated following MARV challenge of NHPs ENSG00000288411 ENSG00000081041 ENSG00000144802 ENSG00000172216 ENSG00000177606 PMC3729625__F5 Cellular Metabolic and Autophagic Pathways: Traffic Control by Redox Signaling PMC3444692__F2 ATF-2 is a nuclear target of p38/Jun N-terminal protein kinase (JNK) ENSG00000149311 ENSG00000170365 ENSG00000125538 PMC4887869__F4 Hydrogen sulfide metabolite trimethylsulfonium is found in human urine PMC5349796__F7 E2 and CTNNB1 signals in the oviductal ciliated and secretory epithelial cells regulating embryo transport ENSG00000088727 ENSG00000129654 ENSG00000168036 PMC7330432__F10 MicroRNA-4500 Inhibits Migration, Invasion, and Angiogenesis of Breast Cancer Cells via RRM2-Dependent MAPK Signaling Pathway ENSG00000132646 ENSG00000171848 PMC1894978__F5 The secretory pathway under different ER stress conditions (t-PA secretion, tunicamycin and DTT) together with examples of genes that are transcriptionally induced or repressed ENSG00000180447 ENSG00000119523 ENSG00000188404 ENSG00000163933 ENSG00000214160 ENSG00000138768 ENSG00000136908 PMC7426153__F5 Microbial Strategies for Survival in the Glass Sponge Vazella pourtalesii ENSG00000159224 ENSG00000182511 ENSG00000122966 ENSG00000078098 ENSG00000198363 ENSG00000102977 PMC3823597__F7 Hypoxia-Induced Changes in the Bioactivity of Cytotrophoblast-Derived Exosomes ENSG00000182718 ENSG00000142798 ENSG00000117400 ENSG00000070404 PMC8931781__F1 Biological Activity of 3-O-Acetyl-11-keto-Beta-Boswellic Acid in Nervous System Diseases ENSG00000125538 ENSG00000136869 ENSG00000116717 ENSG00000079999 PMC5981095__F3 General schematic diagram of molecular events that regulate proliferation, differentiation and the initiation of migration in the SVZ ENSG00000182968 ENSG00000070831 ENSG00000116106 ENSG00000010810 ENSG00000168036 ENSG00000114315 PMC5981095__F5 General schematic of terminal translocation and differentiation in the CP during development ENSG00000177707 ENSG00000111249 ENSG00000110400 ENSG00000136535 ENSG00000182568 ENSG00000116106 ENSG00000291971 ENSG00000170558 ENSG00000168036 ENSG00000176165 ENSG00000173406 ENSG00000109756 PMC11770092__F9 Hypothetical model ENSG00000104856 ENSG00000173933 PMC8100301__F6 Network pharmacology approach to decipher signaling pathways associated with target proteins of NSAIDs against COVID-19 ENSG00000002330 ENSG00000145384 ENSG00000151617 ENSG00000073756 ENSG00000164305 PMC5534294__F5 Signaling pathways underlying podocyte injury in DN ENSG00000163914 ENSG00000168036 ENSG00000067900 PMC9229059__F1 Aphrodisiac Performance of Bioactive Compounds from Mimosa pudica Linn.: In Silico Molecular Docking and Dynamics Simulation Approach ENSG00000175206 ENSG00000002330 ENSG00000169047 ENSG00000172572 ENSG00000088256 ENSG00000169032 ENSG00000137672 ENSG00000113889 ENSG00000171105 ENSG00000285109 ENSG00000070961 ENSG00000116329 ENSG00000116741 ENSG00000169885 ENSG00000159899 ENSG00000067900 ENSG00000197616 ENSG00000182621 ENSG00000107175 ENSG00000043591 ENSG00000101892 ENSG00000120937 ENSG00000278619 ENSG00000118160 ENSG00000120063 ENSG00000164742 ENSG00000117020 ENSG00000108179 ENSG00000145949 ENSG00000026508 PMC7017417__F1 Scheme summarizing transient receptor potential canonical (TRPC) channel isoforms dysregulated under myocardial infarction (MI) and ischemia and reperfusion ENSG00000133107 ENSG00000144935 ENSG00000069018 ENSG00000137672 ENSG00000138741 PMC5685775__F2 Interactions between TGFB1, canonical WNT/Beta-catenin pathway and PPAR G in radiation-induced fibrosis ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC7211126__F1 Schematic depiction of PD-related genes associated with different autophagy pathways ENSG00000129003 ENSG00000100225 ENSG00000158828 ENSG00000069329 PMC5685775__F4 Interactions between TGFB1, canonical WNT/Beta-catenin pathway and PPAR G in radiation-induced fibrosis ENSG00000168036 PMC4926487__F3 Schematic representation of the DNA repair system for neuroprotection implying that genome stability is sustained on several tumor suppressors ENSG00000149311 ENSG00000012048 PMC12189591__F2 Biosynthesis pathway of SFA and MUFA with graph data of fatty acid composition in the plasma of the control and atherosclerosis (AS) group ENSG00000170522 ENSG00000134824 ENSG00000149485 ENSG00000066322 PMC5290251__F1 Nucleotide‐binding oligomerization domain (NOD)‐like receptor (NLR) pro‐inflammatory signalling pathway ENSG00000162711 ENSG00000167207 ENSG00000118503 ENSG00000112851 ENSG00000157625 ENSG00000105483 ENSG00000106100 ENSG00000084774 PMC5723018__F9 FKBP11 affects the formation and progression of AAD ENSG00000125538 ENSG00000100985 ENSG00000162692 ENSG00000134285 PMC12215251__F1 Wnt/Ca2+ signaling pathway, created in BioRender ENSG00000087095 ENSG00000070831 ENSG00000167323 ENSG00000293604 ENSG00000168036 PMC3342110__F1 Signaling pathways important for C PMC3493873__F1 TP53 mutation status-specific network of potential candidate driver genes shown based on their known and predicted functional interactions ENSG00000166167 ENSG00000065361 ENSG00000169047 ENSG00000065559 ENSG00000171791 ENSG00000145386 ENSG00000112715 ENSG00000166851 ENSG00000164742 ENSG00000106571 ENSG00000134057 ENSG00000075218 ENSG00000074410 ENSG00000149554 ENSG00000146648 ENSG00000162104 ENSG00000178568 ENSG00000140443 PMC6660170__F1 Nanoparticle-mediated autophagy ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC3565579__F1 Proposed mechanism for opioid modulation for TLR ENSG00000174125 ENSG00000183735 ENSG00000136869 ENSG00000150455 ENSG00000164342 PMC6262497__F4 JAK-STAT signaling pathway after treatment with N4-Eru ENSG00000134460 ENSG00000105639 PMC6262497__F3 Notch signaling pathway after treatment with N4-Eru ENSG00000273529 ENSG00000133961 ENSG00000114315 PMC3955168__F3 The unfolded protein response (UPR) pathway and its chemical modulators ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC7002394__F10 Insulin signaling cascade targeted by WEE in PA treated HepG2 cells ENSG00000169047 ENSG00000114115 ENSG00000073737 PMC6258353__F3 Proposed biosynthetic pathway for TNL A (1) supported by the isolation of congeners or shunt metabolites 4–11, as indicated by the dashed arrows ENSG00000168884 ENSG00000050730 ENSG00000197429 PMC7306689__F7 Evolution of an Amniote-Specific Mechanism for Modulating Ubiquitin Signaling via Phosphoregulation of the E2 Enzyme UBE2D3 ENSG00000109332 ENSG00000110395 ENSG00000077782 PMC7864817__F1 Metabolic changes induced by DOXO in cardiomyocytes ENSG00000177169 ENSG00000169047 ENSG00000198793 ENSG00000171791 PMC11769378__F3 Activation of TLR2 signaling pathway by bacterial lipoproteins (BLPs) ENSG00000172936 ENSG00000150455 ENSG00000175104 PMC6124166__F1 Schematic model demonstrating how PTH signaling leads to changes in SOST and RANKL expression in osteocytes ENSG00000152266 ENSG00000167941 ENSG00000170145 ENSG00000081189 ENSG00000160741 ENSG00000108840 PMC9386877__F1 Taste transduction and channel synapses in taste buds ENSG00000185933 ENSG00000163982 ENSG00000183128 ENSG00000070985 PMC9523695__F6 Phosphoproteomics reveals that cinobufotalin promotes intrahepatic cholangiocarcinoma cell apoptosis by activating the ATM/CHK2/p53 signaling pathway ENSG00000149311 ENSG00000198793 ENSG00000026103 PMC6643215__F9 Schematic diagram summarizing the anti-NSCLC action of butein via activation of ER stress and ROS generation ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000171791 PMC10474147__F14 Mechanism underlying oxeiptosis ENSG00000156709 ENSG00000247077 ENSG00000079999 PMC7600656__F5 Hepcidin expression via bone morphogenic protein (BMP)-SMAD signaling pathway in hepatocytes ENSG00000170365 ENSG00000010704 ENSG00000106327 ENSG00000187045 ENSG00000072274 PMC3418550__F1 Pathways of SMX metabolism, bio-activation and detoxification, and pathway of GSH biosynthesis ENSG00000005381 PMC6721670__F5 Canonical pathways linked to hNgb binders in a non-stress condition ENSG00000102034 ENSG00000163914 ENSG00000135605 PMC6721670__F6 Upstream regulators and signaling cascades linked to the hNgb protein interactors in a non-stress condition ENSG00000084093 ENSG00000142192 ENSG00000148082 ENSG00000182944 ENSG00000087085 ENSG00000103024 ENSG00000146648 ENSG00000125968 PMC3589124__F7 FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage ENSG00000149311 ENSG00000064393 PMC4821380__F1 EGFR and IGF1R signaling pathways.Notes: Binding of extracellular ligands results in autophosphorylation of key tyrosine residues in the C-terminal domain of EGFR, which allows downstream proteins to bind through their Src homology 2 (SH2) domains ENSG00000169047 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC4859809__F1 MicroRNA biogenesis pathways in cancer ENSG00000100697 ENSG00000092847 ENSG00000124571 ENSG00000128191 ENSG00000113360 ENSG00000134698 ENSG00000123908 PMC4859809__F2 MicroRNA biogenesis pathways in cancer ENSG00000115008 ENSG00000128272 ENSG00000100697 ENSG00000162772 ENSG00000123268 ENSG00000128191 ENSG00000113360 PMC11825590__F4 Portion of the canonical NFKB signaling pathway containing IRAK1 and inflammatory cytokines discussed in this study (IL-1beta, IL-6, and IL-8) ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC5817867__F2 RTK-regulated signaling in breast cancer progression ENSG00000122691 ENSG00000136997 ENSG00000156574 ENSG00000133121 ENSG00000146648 PMC8623831__F4 Treatment of HT29 Human Colorectal Cancer Cell Line with Nanocarrier-Encapsulated Camptothecin Reveals Histone Modifier Genes in the Wnt Signaling Pathway as Important Molecular Cues for Colon Cancer Targeting ENSG00000137673 ENSG00000130826 ENSG00000134982 ENSG00000181555 ENSG00000112118 ENSG00000067900 ENSG00000104332 ENSG00000135341 ENSG00000072364 ENSG00000196586 ENSG00000139218 ENSG00000115464 ENSG00000004478 ENSG00000115884 ENSG00000065978 ENSG00000039319 ENSG00000109084 ENSG00000049130 ENSG00000100354 ENSG00000135446 PMC7072884__F1 Schematic display of G-protein-coupled receptors (GPCRs) signalling in cognitive impairment ENSG00000132906 ENSG00000100290 PMC3509892__F1 Transcriptional Changes Associated with Lack of Lipid Synthesis in Parasitoids ENSG00000173599 ENSG00000099194 ENSG00000062485 ENSG00000026103 PMC6745947__F1 Hepcidin regulation by iron and erythropoiesis ENSG00000170365 ENSG00000010704 ENSG00000106327 ENSG00000187045 ENSG00000178752 PMC10903154__F4 Hippo pathway dysregulation from pancreas precursor lesions to malignancy ENSG00000125398 ENSG00000006712 ENSG00000148926 ENSG00000168610 PMC7811960__F2 Azithromycin effects in the pathophysiology of COVID-19 after receptor-mediated endocytosis, both viral (PAMP) and host released (DAMP) molecules trigger antiviral pathways ENSG00000169245 ENSG00000101751 ENSG00000111537 ENSG00000134982 ENSG00000130234 ENSG00000125538 ENSG00000113520 PMC10903154__F1 Hippo signaling pathway and its network ENSG00000186575 ENSG00000109321 ENSG00000136997 ENSG00000114978 ENSG00000150457 ENSG00000131023 PMC9371685__F4 Sulfur and methane oxidation by a single microorganism ENSG00000179091 ENSG00000163914 ENSG00000188158 ENSG00000166278 ENSG00000102977 PMC3746082__F3 Diabetes mellitus induced regulation of osteoclast ENSG00000291971 ENSG00000198793 ENSG00000145321 ENSG00000121807 ENSG00000175104 PMC3779868__F1 Phosphoinositide signaling and its regulation by phosphatases ENSG00000124102 ENSG00000109452 ENSG00000040933 ENSG00000113263 PMC3746082__F1 Diabetes mellitus induced regulation of osteoblast ENSG00000152266 ENSG00000167941 ENSG00000128791 ENSG00000111341 ENSG00000135914 PMC3746082__F4 Diabetes mellitus induced regulation of skeletal muscle ENSG00000070831 ENSG00000144895 ENSG00000198793 ENSG00000145321 PMC4902960__F6 Activation of NFKB and STATs signaling pathway in ZIKV-infected hNPCs ENSG00000213928 ENSG00000107562 ENSG00000138378 ENSG00000239732 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000168610 ENSG00000121966 ENSG00000164342 PMC8863963__F14 Comprehensive Analysis of the Expression and Prognosis for ITGBs: Identification of ITGB5 as a Biomarker of Poor Prognosis and Correlated with Immune Infiltrates in Gastric Cancer ENSG00000135218 ENSG00000170458 ENSG00000115020 ENSG00000079950 ENSG00000136869 ENSG00000005381 ENSG00000274145 PMC3549317__F1 Lipid synthesis in yeast ENSG00000173599 PMC8863963__F11 Comprehensive Analysis of the Expression and Prognosis for ITGBs: Identification of ITGB5 as a Biomarker of Poor Prognosis and Correlated with Immune Infiltrates in Gastric Cancer ENSG00000177455 ENSG00000103479 ENSG00000169291 ENSG00000002330 ENSG00000179091 ENSG00000010810 ENSG00000186716 ENSG00000163914 ENSG00000104894 ENSG00000198846 ENSG00000152430 PMC4080186__F1 Rho GTPase signaling pathway represents a convergent approach to targeting fibrosis ENSG00000163914 ENSG00000198670 PMC6981023__F6 Graphic summary of the regulation of memory T cell response by mTOR and Stat3 ENSG00000168610 PMC5795459__F1 Canonical type I and III IFN signaling ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000243646 ENSG00000142166 PMC9572342__F9 Fermentation Extract of Naringenin Increases the Expression of Estrogenic Receptor B and Modulates Genes Related to the p53 Signalling Pathway, miR-200c and miR-141 in Human Colon Cancer Cells Exposed to BPA ENSG00000078900 ENSG00000177519 ENSG00000120868 PMC7313026__F2 RNF186, RNF182, and RNF152 are involved in the regulation of the mTORC1 pathway ENSG00000138798 ENSG00000164690 ENSG00000176641 ENSG00000178828 ENSG00000146648 ENSG00000180537 PMC8647434__F1 Targeting Lymphangiogenesis and Lymph Node Metastasis in Liver Cancer ENSG00000170962 ENSG00000117707 ENSG00000112715 ENSG00000150630 PMC8486873__F2 ER stress regulate the secretion of EVs which contained immunomodulatory factors ENSG00000134982 ENSG00000189403 ENSG00000136869 PMC8486873__F3 DNA damage stress induced the release of immunomodulatory cargoes through EVs ENSG00000164430 ENSG00000125538 PMC3970768__F1 The biotin cycle and the known and putative roles ENSG00000171444 ENSG00000173599 PMC7974027__F7 Schematic depicting possiblem echanisms governing the pro-tumorigenesis effect of NET and miR181a targets in the PGRMC1/EGFR–PI3K/Akt/mTOR signaling pathway in breastepithelialMCF10Acells ENSG00000132906 ENSG00000132646 ENSG00000198793 ENSG00000171791 ENSG00000146648 PMC2728746__F7 Proposed model for the mitogen-activated protein kinase kinase 4 (MEK4) regulation of human prostate cell motility and for its inhibition by genistein ENSG00000162889 ENSG00000170365 PMC5336551__F2 Chronic lymphocytic leukaemia ENSG00000162337 ENSG00000161405 ENSG00000182944 ENSG00000122877 ENSG00000168036 ENSG00000169032 ENSG00000179295 ENSG00000177455 ENSG00000171456 ENSG00000136997 ENSG00000184634 ENSG00000137265 ENSG00000174197 ENSG00000128513 ENSG00000215301 ENSG00000198286 ENSG00000109670 ENSG00000162613 ENSG00000023445 ENSG00000185515 ENSG00000105369 ENSG00000157540 ENSG00000157764 ENSG00000173575 ENSG00000115268 ENSG00000137275 ENSG00000078369 ENSG00000007312 ENSG00000127191 ENSG00000149311 ENSG00000115524 ENSG00000183337 ENSG00000102034 ENSG00000170458 ENSG00000186716 ENSG00000172936 ENSG00000131323 PMC6335096__F4 Peroxisome biogenesis ENSG00000198356 ENSG00000124587 ENSG00000288217 PMC6335096__F5 Three mechanisms of pexophagy in mammalian cells ENSG00000149311 ENSG00000177169 ENSG00000188554 ENSG00000124587 ENSG00000288217 ENSG00000157911 ENSG00000108733 ENSG00000164751 PMC4546491__F2 Cytogenomic profiling of breast cancer brain metastases reveals potential for repurposing targeted therapeutics ENSG00000107404 ENSG00000101115 ENSG00000077782 ENSG00000087460 PMC6160397__F5 Proposed model for PD-L1 induction in CC ENSG00000168036 ENSG00000165238 ENSG00000110693 PMC4095565__F2 NOD1 and NOD2 signaling cascades ENSG00000167207 ENSG00000082512 ENSG00000157625 ENSG00000132478 ENSG00000175104 ENSG00000145782 ENSG00000127191 ENSG00000106100 ENSG00000057663 PMC7677640__F1 Mechanism of immune rejection caused by major histocompatibility complex (MHC) mismatch ENSG00000111537 ENSG00000134982 ENSG00000049768 PMC9306018__F1 Diminishing Returns of Mechanical Loading and Potential Mechanisms that Desensitize Osteocytes ENSG00000281324 ENSG00000162337 ENSG00000167941 ENSG00000168036 PMC6008220__F3 Schistosomiasis Induces Persistent DNA Methylation and Tuberculosis-specific Immune Changes ENSG00000111537 ENSG00000062485 PMC6705132__F7 Schematic model for BA-TPQ-induced MCF7 cell apoptosis ENSG00000177606 ENSG00000162772 PMC4985172__F2 Intracellular signaling pathways of EET’s ENSG00000291971 ENSG00000138798 ENSG00000168610 PMC6103459__F1 Cell cycle proteins mediating progression during MI ENSG00000077935 ENSG00000171320 ENSG00000277909 ENSG00000171444 ENSG00000134982 ENSG00000161888 PMC7573295__F1 UCA1 can enhance expression of AKT1 and activate it through phosphorylation ENSG00000198793 ENSG00000168610 ENSG00000159399 PMC5133678__F7 RBM5 targets in the EGFR Signaling pathway ENSG00000140992 ENSG00000002330 ENSG00000070831 ENSG00000115904 ENSG00000169032 ENSG00000137845 ENSG00000124762 ENSG00000179295 ENSG00000111837 ENSG00000150907 ENSG00000136158 ENSG00000132906 ENSG00000152495 ENSG00000165059 ENSG00000143933 ENSG00000184481 ENSG00000148848 ENSG00000160691 ENSG00000123360 ENSG00000196961 ENSG00000081913 ENSG00000164056 ENSG00000101255 ENSG00000148204 ENSG00000154678 ENSG00000183020 ENSG00000040199 ENSG00000122705 ENSG00000105723 PMC5260980__F4 Signaling pathways at the crossroad between autophagy and EMT ENSG00000291971 ENSG00000198793 ENSG00000158796 ENSG00000168610 PMC3901523__F3 Signaling pathways for inner ear proliferation and differentiation ENSG00000129355 ENSG00000114315 ENSG00000124762 ENSG00000172238 PMC5260980__F2 Autophagy and epithelial–mesenchymal transition: an intricate interplay in cancer ENSG00000169554 ENSG00000041982 ENSG00000138798 PMC8522258__F4 Synergistic metabolic pathways that lead to a hyaluronan storm, NETosis, coagulopathy, and immune suppression ENSG00000170961 ENSG00000115415 ENSG00000096717 ENSG00000168610 ENSG00000146648 PMC2661888__F3 Hypergraph representation of the Boolean model for yeast glucose repression ENSG00000069482 ENSG00000158428 ENSG00000124253 PMC8388496__F4 Comprehensive Transcriptomic Comparison between Porcine CD8− and CD8+ Gamma Delta T Cells Revealed Distinct Immune Phenotype ENSG00000139193 ENSG00000277336 ENSG00000168329 ENSG00000112964 ENSG00000100906 ENSG00000007312 ENSG00000177455 ENSG00000186810 ENSG00000111537 ENSG00000102245 ENSG00000184371 ENSG00000049249 ENSG00000275095 ENSG00000160293 ENSG00000155629 ENSG00000135605 ENSG00000143184 ENSG00000026103 ENSG00000141655 PMC2880865__F8 Revitalization of a diastemal bud ENSG00000136158 ENSG00000070193 ENSG00000164690 PMC2895370__F1 TLR4 signaling: The MyD88-dependent pathway through PDCD4 ENSG00000172936 ENSG00000136869 PMC4597143__F4 Quantification of the full chemotaxis pathway ENSG00000140992 ENSG00000138639 ENSG00000175866 ENSG00000102606 ENSG00000153823 ENSG00000134982 ENSG00000138443 ENSG00000158195 ENSG00000100852 ENSG00000124126 ENSG00000254999 ENSG00000061676 ENSG00000128617 ENSG00000149781 ENSG00000136002 ENSG00000159788 ENSG00000112290 ENSG00000148498 ENSG00000107263 ENSG00000076928 ENSG00000126247 ENSG00000173599 ENSG00000090104 ENSG00000065559 ENSG00000116741 ENSG00000267534 ENSG00000120063 ENSG00000116584 ENSG00000170989 ENSG00000002330 ENSG00000070831 ENSG00000291971 ENSG00000095015 ENSG00000168036 ENSG00000158517 ENSG00000169032 ENSG00000121879 ENSG00000092820 ENSG00000089159 ENSG00000113263 ENSG00000157764 ENSG00000109320 ENSG00000173039 ENSG00000281614 ENSG00000177189 ENSG00000120899 ENSG00000067606 ENSG00000010810 ENSG00000177606 ENSG00000015285 ENSG00000115020 PMC3662220__F1 Novel zebrafish model reveals a critical role for mapk in lymphangiogenesis PMC9498168__F8 MiR-942-3p as a Potential Prognostic Marker of Gastric Cancer Associated with AR and MAPK/ERK Signaling Pathway ENSG00000163618 ENSG00000119508 ENSG00000127528 ENSG00000124571 ENSG00000145386 ENSG00000136231 ENSG00000186081 ENSG00000131914 ENSG00000130477 ENSG00000171241 ENSG00000237515 ENSG00000152208 ENSG00000101958 ENSG00000162374 ENSG00000105810 ENSG00000082556 ENSG00000120251 ENSG00000147536 ENSG00000136108 ENSG00000154096 ENSG00000142408 ENSG00000136982 ENSG00000115008 ENSG00000138346 ENSG00000035499 ENSG00000165891 ENSG00000092853 ENSG00000115415 ENSG00000243709 ENSG00000080839 PMC7456945__F6 Simplified metabolic network indicating major pathways of volatile organic compound (VOC) synthesis and associated CO2 decarboxylation processes in the light ENSG00000197429 PMC7595122__F1 Caspase-3/GSDME signal pathway as a switch between apoptosis and pyroptosis in cancer ENSG00000278718 ENSG00000132906 ENSG00000137757 ENSG00000125538 ENSG00000196954 ENSG00000168040 ENSG00000164305 PMC9534090__F4 Emergence and dissemination of monkeypox, an intimidating global public health problem ENSG00000213928 ENSG00000111537 ENSG00000144895 ENSG00000134982 ENSG00000131323 ENSG00000175104 PMC7595122__F3 Graphical model of the effect of various molecules on caspase-3 dependent tumor cells death ENSG00000132906 ENSG00000164305 PMC12179916__F5 Myosin heavy chain 9 activates the Wnt/Beta-catenin signaling pathway to enhance the proliferation and survival of cancer cells ENSG00000100345 ENSG00000168036 PMC11537654__F4 Homoharringtonine (HHT) enhances the proapoptotic effects of venetoclax by inhibiting the MAPK/ERK and PI3K/AKT pathways and activating the p53 pathway (orange line) ENSG00000149311 ENSG00000175054 PMC3705993__F1 LRP5, LRP6 and LRP4 are important components of the Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000134569 ENSG00000168036 ENSG00000206177 ENSG00000104332 PMC8126980__F4 Ferroptosis in infection, inflammation, and immunity ENSG00000104365 ENSG00000105329 ENSG00000100906 ENSG00000269335 ENSG00000213341 ENSG00000127666 ENSG00000168610 ENSG00000276561 ENSG00000183735 ENSG00000108691 ENSG00000164430 ENSG00000263528 ENSG00000177606 ENSG00000189403 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC8505885__F1 Metabolic Program of Regulatory B Lymphocytes and Influence in the Control of Malignant and Autoimmune Situations ENSG00000180210 ENSG00000143158 ENSG00000150907 ENSG00000186716 ENSG00000137265 ENSG00000196092 ENSG00000131323 ENSG00000168610 ENSG00000159399 ENSG00000133818 PMC3081180__F7 The participation of MCP-1, TNFA, MMP-9, E-cadherin, and Beta-catenin in macrophage fusion ENSG00000100985 ENSG00000121807 PMC9393846__F1 Chromosome instability and aneuploidy as context-dependent activators or inhibitors of antitumor immunity ENSG00000164430 ENSG00000134982 ENSG00000231179 ENSG00000204520 PMC4863308__F1 Hedgehog (Hh) signaling.Notes: Normal activation of the signaling pathway results from the binding of Hh ligand to the 12-transmembrane patched 1 (PTCH1) ENSG00000128602 PMC8505885__F2 Metabolic Program of Regulatory B Lymphocytes and Influence in the Control of Malignant and Autoimmune Situations ENSG00000239732 ENSG00000186716 ENSG00000168610 ENSG00000106546 PMC6113163__F4 Signaling Pathway of Rho Guanine Nucleotide Exchange FactorImportant functions of this pathway involve antiapoptotic actions and regulation of actin-myosin interaction ENSG00000070831 ENSG00000122966 ENSG00000140575 ENSG00000106299 ENSG00000108443 ENSG00000105647 ENSG00000067900 ENSG00000131941 ENSG00000121879 ENSG00000108518 ENSG00000111348 ENSG00000133055 ENSG00000061938 ENSG00000114993 ENSG00000106683 ENSG00000076928 ENSG00000163914 ENSG00000015285 ENSG00000123143 ENSG00000171608 PMC11537654__F2 Homoharringtonine (HHT) causes phosphorylated eukaryotic initiation factor 4E (p-eIF4E) to SUMOize more fully ENSG00000132109 ENSG00000087253 ENSG00000117215 ENSG00000198793 ENSG00000123374 ENSG00000137845 ENSG00000184900 PMC3446326__F1 Alterations in the FGFR signalling pathway that influence breast cancer ENSG00000066468 ENSG00000160867 ENSG00000077782 PMC11537654__F3 Combination of homoharringtonine (HHT) and quizartinib inhibits the FLT3-AKT signaling pathway and its downstream targets (purple line) ENSG00000122025 ENSG00000198793 PMC11537654__F1 Homoharringtonine (HHT) directly binds the nuclear factor-kappa B (NF-KB) repression factor (NKRF) through the second double-strand RNA-binding motif (DSRM2), a nuclear localization signal for NKRF ENSG00000122025 ENSG00000104814 ENSG00000138336 ENSG00000078399 ENSG00000198793 ENSG00000136997 ENSG00000185591 ENSG00000166278 ENSG00000143995 PMC7339185__F12 Regulation mechanism of miR‐128‐3p in BCSCs ENSG00000117650 ENSG00000161921 ENSG00000272398 ENSG00000026508 ENSG00000168036 ENSG00000146648 PMC4022581__F4 Transcriptome Profiling of the Theca Interna in Transition from Small to Large Antral Ovarian Follicles ENSG00000049323 ENSG00000101670 ENSG00000119888 ENSG00000171791 ENSG00000119681 ENSG00000138356 ENSG00000150991 ENSG00000003989 ENSG00000077420 ENSG00000069849 ENSG00000165730 ENSG00000026508 ENSG00000140391 ENSG00000243646 ENSG00000013297 ENSG00000088992 ENSG00000142546 ENSG00000120594 ENSG00000187955 ENSG00000016402 PMC9483763__F1 Current Review in Basic Science: Animal Models of Focal Cortical Dysplasia and Epilepsy ENSG00000100150 ENSG00000114388 PMC4041457__F4 The SDSA (synthesis-dependent strand annealing) and DSB repair sub-pathways ENSG00000178295 ENSG00000154920 ENSG00000188827 ENSG00000197299 ENSG00000178966 PMC6349324__F1 Role of tumor-associated neutrophils in regulation of tumor growth in lung cancer development: A mathematical model ENSG00000138798 ENSG00000136997 PMC8607427__F2 Post-translational modifications of CDK5 and their biological roles in cancer PMC8607427__F3 Post-translational modifications of CDK5 and their biological roles in cancer ENSG00000188486 ENSG00000149311 ENSG00000154920 ENSG00000162493 ENSG00000123374 ENSG00000168610 ENSG00000146648 PMC6743755__F3 Petri net–based model of the human DNA base excision repair pathway ENSG00000132646 ENSG00000039650 PMC6810723__F4 Network structure of the 66 genes (left figure) and the top 12 selected genes listed in (right figure) from KEGG “Drug metabolism-cytochrome P450” pathway, extracted using the R package KEGGgraph ENSG00000165841 ENSG00000197408 ENSG00000140505 ENSG00000130649 ENSG00000143198 ENSG00000255974 ENSG00000085871 ENSG00000131781 ENSG00000138356 PMC3563076__F2 Molecules involved during pancreatic development ENSG00000099330 ENSG00000125398 ENSG00000139515 ENSG00000129514 ENSG00000182759 ENSG00000168267 ENSG00000122859 ENSG00000106331 ENSG00000196767 PMC7602498__F1 Homocysteine (Hcy) metabolic pathway ENSG00000205221 PMC4900455__F2 Reciprocal antagonism by TLR4 oncogenic and TGFB tumor suppressor pathways ENSG00000168610 ENSG00000136231 PMC5962335__F4 Nicotinamide Adenine Dinucleotide Metabolism and Neurodegeneration ENSG00000105835 ENSG00000291814 ENSG00000123572 ENSG00000278488 PMC3947295__F1 Scheme of the metabolic pathway of n-6 and n-3 long-chain polyunsaturated fatty acids ENSG00000134824 ENSG00000149485 ENSG00000197977 PMC8715940__F6 Therapeutic Mechanism and Key Alkaloids of Uncaria rhynchophylla in Alzheimer’s Disease From the Perspective of Pathophysiological Processes ENSG00000140992 ENSG00000104365 ENSG00000110330 ENSG00000002330 ENSG00000198793 ENSG00000197442 ENSG00000101266 ENSG00000213341 ENSG00000121879 ENSG00000073756 ENSG00000164305 ENSG00000007171 ENSG00000143387 ENSG00000133019 ENSG00000178607 ENSG00000143801 ENSG00000109861 ENSG00000177606 ENSG00000171608 ENSG00000145349 PMC9482625__F3 Cellular composition within the TME and the effect of EMT on TKI resistance ENSG00000167601 ENSG00000019991 ENSG00000169554 ENSG00000108691 ENSG00000275718 ENSG00000122691 ENSG00000163235 ENSG00000124882 ENSG00000168036 PMC8715940__F7 Therapeutic Mechanism and Key Alkaloids of Uncaria rhynchophylla in Alzheimer’s Disease From the Perspective of Pathophysiological Processes ENSG00000002330 ENSG00000281324 ENSG00000134982 ENSG00000169047 ENSG00000198793 ENSG00000168036 ENSG00000101266 ENSG00000169032 ENSG00000121879 ENSG00000164305 ENSG00000125084 ENSG00000133019 ENSG00000143801 ENSG00000138613 ENSG00000196549 ENSG00000198838 ENSG00000205155 ENSG00000165879 ENSG00000132906 ENSG00000171105 ENSG00000107404 ENSG00000109320 ENSG00000143933 ENSG00000213341 ENSG00000127191 ENSG00000073756 ENSG00000007171 ENSG00000128272 ENSG00000171608 PMC6715281__F1 Wnt signaling pathways and the regulation by Wnt antagonists and the bone microenvironment ENSG00000134086 ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000132478 PMC9393259__F1 Underlying pathological mechanism of ferroptosis in the development of cardiovascular disease ENSG00000151012 ENSG00000167468 PMC9482625__F4 Impact of tumor metabolic reprogramming on TKI drug resistance ENSG00000019991 ENSG00000135218 ENSG00000092621 ENSG00000169710 ENSG00000185591 ENSG00000146648 PMC8715940__F5 Therapeutic Mechanism and Key Alkaloids of Uncaria rhynchophylla in Alzheimer’s Disease From the Perspective of Pathophysiological Processes ENSG00000167601 ENSG00000140992 ENSG00000168329 ENSG00000171105 ENSG00000002330 ENSG00000198793 ENSG00000197442 ENSG00000121879 ENSG00000073756 ENSG00000168610 ENSG00000164305 ENSG00000196549 ENSG00000177606 PMC11955630__F9 Pathway analysis for CKS1B and related genes ENSG00000157404 ENSG00000157764 ENSG00000115904 ENSG00000164327 ENSG00000141564 ENSG00000047936 ENSG00000169032 ENSG00000179295 ENSG00000183765 ENSG00000149311 ENSG00000122025 ENSG00000066468 ENSG00000117020 ENSG00000177189 ENSG00000110395 ENSG00000134853 ENSG00000143622 ENSG00000077782 ENSG00000146648 ENSG00000178568 ENSG00000196712 ENSG00000140443 PMC8170402__F2 Molecular Mechanisms of Specific Cellular DNA Damage Response and Repair Induced by the Mixed Radiation Field During Boron Neutron Capture Therapy ENSG00000149311 ENSG00000012048 ENSG00000051180 ENSG00000139618 PMC3081924__F10 Model for SENP2-mediated modulation of Mdm2 in regulating p53 ENSG00000163904 ENSG00000140464 PMC7744508__F1 Central carbon metabolism network, which was implemented in the multi-level kinetic model of Synechocystis ENSG00000261701 ENSG00000115271 PMC9393259__F2 Underlying pathological mechanism of ferroptosis in the development of cardiovascular disease ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC11989024__F3 Cellular signalings and mechanisms of integrin-mediated drug resistance in cancer cells ENSG00000291971 ENSG00000198793 ENSG00000146648 PMC6625751__F1 Type I interferon in rheumatic diseases ENSG00000125347 ENSG00000276561 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000170458 ENSG00000136869 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC5649010__F8 Model for atypical MyD88-independent TLR7 signaling during Yersinia pestis infection ENSG00000102189 ENSG00000172936 PMC5449407__F7 SAR signaling in maize inflorescence based on DEG analysis ENSG00000084774 PMC8929255__F4 Immune barriers in haematopoietic stem cell gene therapy ENSG00000149311 ENSG00000164430 ENSG00000111537 PMC5153247__F8 Schematic diagram of Akt/Id2 signaling pathway in the neuron ENSG00000164879 PMC7729279__F2 Illustration of molecular signaling involved in SARS-CoV-2 infection ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000115415 ENSG00000130234 ENSG00000125538 ENSG00000184012 ENSG00000172936 ENSG00000276561 ENSG00000142166 PMC12061301__F7 AKT1 regulating cuproptosis in TNBC tumorigenesis ENSG00000137714 PMC8591232__F2 Targeting Macrophage Dysregulation for Viral Infections: Novel Targets for Immunomodulators ENSG00000111537 ENSG00000163739 ENSG00000168610 PMC4284697__F1 Summary of the p53 pathway ENSG00000134574 ENSG00000116717 ENSG00000078237 ENSG00000158169 ENSG00000284194 ENSG00000095002 ENSG00000140464 ENSG00000285069 PMC9356848__F7 Transmembrane Protein ANTXR1 Regulates Gamma-Globin Expression by Targeting the Wnt/Beta-Catenin Signaling Pathway ENSG00000134982 ENSG00000168036 ENSG00000110693 PMC5095106__F3 TNFR1-elicited signaling pathways ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000127191 ENSG00000143258 PMC8492288__F2 Tryptophan-Kynurenine Pathway in COVID-19-Dependent Musculoskeletal Pathology: A Minireview ENSG00000125968 ENSG00000106546 PMC8170847__F2 Developmental Pathway and Interconnectivity of Immunotherapy and Nanotechnology: ENSG00000214285 PMC9312905__F7 Klotho Modulates Pro-Fibrotic Activities in Human Atrial Fibroblasts through Inhibition of Phospholipase C Signaling and Suppression of Store-Operated Calcium Entry ENSG00000042832 ENSG00000167323 ENSG00000137672 PMC8431116__F2 MYC Rules: Leading Glutamine Metabolism toward a Distinct Cancer Cell Phenotype ENSG00000086730 ENSG00000115419 ENSG00000167701 PMC5190058__F8 Combination of gemcitabine-containing magnetoliposome and oxaliplatin-containing magnetoliposome in breast cancer treatment: A possible mechanism with potential for clinical application ENSG00000104499 PMC8536196__F1 Association and Genetic Expression between Genes Involved in HPA Axis and Suicide Behavior: A Systematic Review ENSG00000182628 ENSG00000145708 ENSG00000185231 PMC7460555__F1 PI3K/Akt/mTOR, ERK1/2-MAPK, and Wnt/Beta-catenin pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000102104 PMC6023907__F3 The BMP signaling cascade in osteoblast differentiation ENSG00000137834 ENSG00000140262 ENSG00000122691 ENSG00000120149 PMC3757225__F7 Mechanistic model of strain-induced fetal type II cell differentiation via integrin-TACE pathway ENSG00000163235 ENSG00000113070 ENSG00000146648 PMC6894473__F1 Schematic view of the Wnt signaling pathways between MSCs and HCC cells in inflammation microenvironment ENSG00000178860 ENSG00000111537 ENSG00000281324 ENSG00000162337 ENSG00000119888 ENSG00000134982 ENSG00000164362 ENSG00000105656 ENSG00000168036 PMC3260150__F2 Identification of a Potential Ovarian Cancer Stem Cell Gene Expression Profile from Advanced Stage Papillary Serous Ovarian Cancer ENSG00000002330 ENSG00000064225 ENSG00000254685 PMC6894473__F2 Schematic view of the TLR4 signaling pathways between MSCs and HCC cells in inflammation microenvironment ENSG00000178860 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC6894473__F3 Schematic view of the AP-1 and PKB signaling pathways between MSCs and HCC cells in inflammation microenvironment ENSG00000178860 ENSG00000002330 ENSG00000198793 ENSG00000175104 PMC7503096__F1 Two common pathways implicated in thyroid cancer ENSG00000198793 ENSG00000164362 PMC7699912__F1 Toll-like receptors (TLR)-mediated signaling pathway in keratinocytes ENSG00000174125 ENSG00000226275 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000136869 ENSG00000276561 ENSG00000164342 PMC2956794__F1 Targeting DNA repair proteins for cancer treatment ENSG00000149311 ENSG00000012048 ENSG00000105486 ENSG00000132646 ENSG00000170430 ENSG00000051180 ENSG00000136936 ENSG00000139618 PMC8441939__F1 Immune response to SARS‐CoV‐2 in children: A review of the current knowledge ENSG00000213928 PMC5904130__F5 Signaling pathways responsible for the rapid antidepressant-like effects of a GluN2A-preferring NMDA receptor antagonist ENSG00000198793 PMC10530696__F1 Deciphering the Enigmatic Influence: Non-Coding RNAs Orchestrating Wnt/Beta-Catenin Signaling Pathway in Tumor Progression ENSG00000134982 ENSG00000281406 ENSG00000124766 ENSG00000168036 ENSG00000185591 PMC4583389__F3 Systems Analysis of Adaptive Responses to MAP Kinase Pathway Blockade in BRAF Mutant Melanoma ENSG00000169752 PMC8838558__F7 One-Carbon Metabolism in Alzheimer’s Disease and Parkinson’s Disease Brain Tissue ENSG00000116984 PMC6317074__F1 Proposed cholesterol-lowering mechanisms of PS ENSG00000138075 ENSG00000130164 ENSG00000015520 ENSG00000120437 ENSG00000143921 PMC6834139__F2 ST2/IL-33 immune cells signaling pathway ENSG00000019991 ENSG00000111537 ENSG00000105329 ENSG00000137033 ENSG00000172936 ENSG00000184216 PMC9188347__F1 Metabolites as drivers and targets in rheumatoid arthritis ENSG00000102794 ENSG00000159399 PMC8990477__F2 CAR-T Cell Therapy for Breast Cancer: From Basic Research to Clinical Application ENSG00000198793 ENSG00000136997 ENSG00000171791 PMC8998551__F4 Solid Tumors and Kinase Inhibition: Management and Therapy Efficacy Evolution ENSG00000122025 ENSG00000157404 ENSG00000198793 ENSG00000134853 PMC2733795__F4 Regulation of STAT3 signal transduction pathway ENSG00000168610 PMC11544397__F6 ERS induces renal fibrosis in high-fat diet mice via the TGFB/SMAD pathway PMC4276042__F1 Targeting the PI3K pathway for cancer therapy ENSG00000002330 PMC9180737__F3 GLIS1-3: Links to Primary Cilium, Reprogramming, Stem Cell Renewal, and Disease ENSG00000169379 ENSG00000168610 PMC9180737__F2 GLIS1-3: Links to Primary Cilium, Reprogramming, Stem Cell Renewal, and Disease ENSG00000124216 ENSG00000174332 ENSG00000077782 PMC6750892__F11 Proposed mechanism for how AvB3 integrin signaling could be mediating fibronectin matrix assembly in TM cells ENSG00000291971 PMC11054193__F7 DEGs and DMs change following exogenous ABA therapy and UV-B stress in the R ENSG00000160752 ENSG00000113161 ENSG00000167508 PMC7316593__F8 RSV induces Uric acid and leads to Th2 response ENSG00000108691 ENSG00000137033 ENSG00000125538 ENSG00000145777 PMC3493902__F8 The diagram illustrates the possible mechanism of tumor cells-secreted CCN1 in regulation of pancreatic carcinogenesis through the regulation of SHh signaling ENSG00000118816 ENSG00000164690 ENSG00000128602 PMC8093976__F4 Insights into the regulatory role of Plexin D1 signalling in cardiovascular development and diseases ENSG00000170381 ENSG00000128917 ENSG00000163914 ENSG00000004399 PMC5751130__F1 Regulation of the TGFB signaling pathway by miRNAs PMC5159651__F7 Suggested model for modulation of Wnt pathway by OCC-1 splice variants ENSG00000134982 ENSG00000115266 ENSG00000168036 ENSG00000136044 PMC11274024__F6 Different cellular events in RG7388-resistant CLL samples ENSG00000174307 ENSG00000172667 ENSG00000105327 ENSG00000134574 ENSG00000132646 ENSG00000120889 ENSG00000164938 ENSG00000181026 ENSG00000124762 ENSG00000136048 ENSG00000173530 ENSG00000026103 PMC8093976__F2 Insights into the regulatory role of Plexin D1 signalling in cardiovascular development and diseases ENSG00000170381 ENSG00000075223 ENSG00000004399 PMC8093976__F3 Insights into the regulatory role of Plexin D1 signalling in cardiovascular development and diseases ENSG00000075223 ENSG00000153993 ENSG00000165527 ENSG00000004399 ENSG00000112715 PMC8593325__F3 Cleaved PINK1 in Neuronal Development, Synaptogenesis, and Plasticity: Implications for Parkinson’s Disease ENSG00000175193 ENSG00000158828 PMC10454494__F3 Prostate cancer pathways [112] ENSG00000002330 PMC5000709__F2 Kallistatin inhibits angiogenesis and inflammation through blocking VEGF signaling and NADPH oxidase activity ENSG00000291971 ENSG00000005882 ENSG00000112715 PMC5000709__F3 Kallistatin inhibits Wnt canonical pathway induced angiogenesis and inflammation ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000168036 PMC8437644__F7 Studies on the Role of circRNAs in Osteoarthritis ENSG00000136457 ENSG00000135218 PMC7415495__F6 Molecular mechanisms underlying Beta-cryptoxanthin inhibits A7-nAChR, thereby leading to the inhibition of lung cancer progression and metastasis ENSG00000262406 ENSG00000087245 ENSG00000002330 ENSG00000100985 PMC4249256__F5 Illustration of the proposed crosstalk between insulin/IGF1 and IL-17 signaling pathways ENSG00000163739 ENSG00000175104 ENSG00000115009 ENSG00000163702 PMC3730126__F1 Molecular mechanisms of cellular insulin resistance in muscle and liver ENSG00000042832 ENSG00000169047 ENSG00000285482 ENSG00000062282 PMC4460810__F1 Wnt/Beta-catenin pathway regulates stem cell pluripotency and cell fate decisions during development ENSG00000134982 ENSG00000136997 ENSG00000026508 ENSG00000168036 PMC5328691__F1 Nuclear Receptors Resolve Endoplasmic Reticulum Stress to Improve Hepatic Insulin Resistance ENSG00000128272 ENSG00000100219 PMC7415495__F3 Molecular mechanisms underlying Beta-cryptoxanthin prevention of cancer development/progression ENSG00000087245 ENSG00000135697 ENSG00000100985 ENSG00000096717 PMC2689231__F6 Purine biosynthetic pathway, showing protein abundance changes for the P ENSG00000156110 ENSG00000185129 ENSG00000146676 PMC7162828__F1 Kynurenine pathway of tryptophan degradation ENSG00000183077 PMC7388725__F2 Mitochondria and lysosomes in ferroptosis ENSG00000182511 ENSG00000135423 ENSG00000167468 ENSG00000172005 ENSG00000122873 ENSG00000168610 ENSG00000115107 PMC8778447__F1 Molecular Mechanisms Leading from Periodontal Disease to Cancer ENSG00000157764 ENSG00000168610 PMC3502626__F7 A theoretical model of synergistic interactions between resveratrol and HDAC inhibitors is presented ENSG00000132906 ENSG00000173039 ENSG00000096717 ENSG00000064012 ENSG00000164305 PMC5328691__F2 Nuclear Receptors Resolve Endoplasmic Reticulum Stress to Improve Hepatic Insulin Resistance ENSG00000128272 ENSG00000163703 ENSG00000173846 PMC7388725__F1 Ferroptosis in a cell ENSG00000135423 ENSG00000196839 ENSG00000197429 ENSG00000113161 ENSG00000111684 ENSG00000115107 PMC5938095__F8 TrkB-mediated activation of the phosphatidylinositol-3-kinase/Akt cascade reduces the damage inflicted by oxygen-glucose deprivation in area CA3 of the rat hippocampus ENSG00000164879 ENSG00000173599 PMC3045483__F1 Interactions occuring in the ovarian mural granulosa cells (GC) and cumulus cells (CC) after the administration of hCG for ovulation induction ENSG00000082175 ENSG00000109321 ENSG00000124882 ENSG00000145321 PMC6628048__F1 Synthesis of bile acids (BA) ENSG00000167910 ENSG00000036530 ENSG00000180432 ENSG00000135929 PMC3215729__F1 Rv2607 from Mycobacterium tuberculosis Is a Pyridoxine 5′-Phosphate Oxidase with Unusual Substrate Specificity ENSG00000291814 ENSG00000139515 ENSG00000102007 PMC3947125__F3 Schematic model of the autophagy pathway demonstrates several relevant markers of autophagy which are potentially influenced by a high cholesterol diet as well as possible points of regulation try resveratrol (RV) ENSG00000198793 ENSG00000005893 ENSG00000145782 ENSG00000057663 PMC4533011__F1 iNKT cell activation pathways in sepsis ENSG00000158473 ENSG00000170458 ENSG00000134982 ENSG00000281857 PMC6811614__F1 GCs affect cross-talk of bone cells and their communication with muscle, vasculature and myeloid cell-derived osteoclasts ENSG00000178860 ENSG00000156076 ENSG00000167941 PMC7720507__F6 Internalization pathway of PLGA-PEI PCS NPs in MSCs ENSG00000102189 ENSG00000214285 ENSG00000154059 ENSG00000110651 ENSG00000010278 ENSG00000135404 PMC7175615__F5 Pathway of TGFB2-TLR4 crosstalk within the glaucomatous TM ENSG00000095739 ENSG00000172936 ENSG00000136869 PMC5256872__F7 Transcriptome Sequencing Reveals Key Pathways and Genes Associated with Cisplatin Resistance in Lung Adenocarcinoma A549 Cells ENSG00000067900 ENSG00000060566 ENSG00000100739 ENSG00000102302 ENSG00000114279 ENSG00000182541 PMC6368372__F1 Proposed mechanisms of action of glutamatergic modulators and other putative rapid-acting antidepressants ENSG00000284161 ENSG00000167658 PMC8965725__SF1 Targeted delivery of a STING agonist to brain tumors using bioengineered protein nanoparticles for enhanced immunotherapy ENSG00000164430 ENSG00000214285 PMC9526507__F2 Notch Signaling Pathway Contributes to Angiogenesis and Tumor Immunity in Breast Cancer ENSG00000176692 ENSG00000135547 ENSG00000128917 ENSG00000148400 PMC9526507__F1 Notch Signaling Pathway Contributes to Angiogenesis and Tumor Immunity in Breast Cancer ENSG00000283780 ENSG00000128917 ENSG00000137845 ENSG00000090932 PMC7909764__F3 Senolytic therapies ENSG00000141867 ENSG00000135446 ENSG00000164830 PMC5987016__F1 “Immune Gate” of psychopathology – mechanisms of gut derived immune activation leading to psychiatric manifestations ENSG00000197971 ENSG00000136869 ENSG00000237834 PMC4457640__F3 Protein Cys map to functional pathways based upon percent oxidation ENSG00000115484 ENSG00000169371 ENSG00000291971 ENSG00000169710 ENSG00000132341 PMC2901795__F1 Left: the EGFR pathway; Right: inhibition of the EGFR pathway by the EGFR monoclonal antibodies ENSG00000163235 ENSG00000138798 ENSG00000146648 PMC5799794__F1 Effects and underlying mechanisms of lncRNAs in various fibroses ENSG00000169554 ENSG00000221866 ENSG00000140564 ENSG00000142973 ENSG00000105329 ENSG00000172936 ENSG00000001626 PMC7491749__F1 Ras Signaling Pathway ENSG00000115904 PMC11019826__F8 Utility of l-carnitine for preventing liver tumors derived from metabolic dysfunction–associated steatohepatitis ENSG00000111859 PMC7491749__F4 Overcoming Resistance to Drugs Targeting KRASG12C Mutation ENSG00000115904 ENSG00000087586 PMC9347104__F1 Oxalate-induced apoptosis through ERS-ROS–NFKB signalling pathway in renal tubular epithelial cell ENSG00000100219 PMC4892757__F1G MicroRNAs targeting TGFB signalling underlie the regulatory T cell defect in multiple sclerosis ENSG00000049768 PMC11277110__F2 Roles of miRNAs involved in the developmental growth and apoptosis of Drosophila ENSG00000157933 PMC11277110__F4 Signaling pathways regulated by miRNAs in wing development ENSG00000116729 ENSG00000134982 ENSG00000128602 PMC3648790__F4 Interplay Between the Cancer Genome and Epigenome ENSG00000198901 ENSG00000163930 ENSG00000143970 ENSG00000162521 ENSG00000008083 PMC3213224__F3 Possible mechanism of reciprocal enhancement between innate and adaptive immunity, through NF-kB and STAT-1/IRF-1 pathway ENSG00000169245 ENSG00000186810 ENSG00000115415 ENSG00000138755 PMC10959754__F4 Ubiquitination in TNF signaling ENSG00000137275 ENSG00000102871 ENSG00000157625 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000154124 ENSG00000127191 ENSG00000285379 PMC11672279__S1 The brain‐targeting and therapeutic mechanism of T+A@Glu‐NPs against glioma ENSG00000141867 ENSG00000148400 ENSG00000214285 PMC6566291__F1 TGF-Beta-mediated skeletal muscle fibrosis PMC4508827__F5 Toll signalling pathway of C ENSG00000130164 ENSG00000105298 ENSG00000172936 ENSG00000185591 ENSG00000168040 ENSG00000175104 PMC4508827__F7 Jak-Stat pathway of C ENSG00000135446 ENSG00000033800 ENSG00000123374 PMC9476258__F2 The potential of plant extracts in cell therapy ENSG00000170365 ENSG00000134982 ENSG00000168036 PMC6688483__F4 Role of CRPs in AIBD ENSG00000134757 ENSG00000196352 ENSG00000134760 PMC8136123__F5 Histone deacetylase-2: A potential regulator and therapeutic target in liver disease (Review) ENSG00000138798 ENSG00000198793 ENSG00000196591 PMC8184824__F6 HJURP in PCa cells ENSG00000123485 ENSG00000124762 PMC5033061__F6 An integrative analysis of the InR/PI3K/Akt network identifies the dynamic response to Insulin signaling ENSG00000126016 ENSG00000163435 ENSG00000163918 ENSG00000168036 ENSG00000120438 ENSG00000133119 ENSG00000128191 ENSG00000113360 PMC3770492__F2 A new Vitreoscilla filiformis extract grown on spa water-enriched medium activates endogenous cutaneous antioxidant and antimicrobial defenses through a potential Toll-like receptor 2/protein kinase C, zeta transduction pathway ENSG00000067606 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000168610 ENSG00000184216 ENSG00000115009 PMC7576355__F5 FGFR axis, Ras-Raf-MEK and TP53 relationship to CDK4/6; FGFR results in activation of PI3K, Ras-Raf-MEK, STAT which increases cyclin D1, thereby promoting progression through the cell cycle ENSG00000135446 ENSG00000123374 PMC7576355__F2 CDK4/6 pathway and FOXO3-FOXM1 axis: Cyclin D-CDK4/6 complex phosphorylates FOXM1 transcription factor which is involved in expression of G1/S phase genes ENSG00000135446 ENSG00000105810 PMC7598587__F7 Putative molecular pathway of catalpol in the skeletal muscle of type-2 diabetic mice in amelioration of glucose homeostasis and insulin sensitivity ENSG00000169047 ENSG00000096717 ENSG00000062485 PMC7576355__F3 Speckle-type POZ protein (SPOP) and CDK4/6 pathway ENSG00000135446 ENSG00000121067 ENSG00000105810 PMC7576355__F1 Androgen regulation of cell cycle and CDK4/6 pathway ENSG00000291971 ENSG00000198793 PMC5972548__F2 Wnt signaling pathways ENSG00000169071 ENSG00000163914 ENSG00000168036 PMC2671988__F2 Autism-specific copy number variants further implicate the phosphatidylinositol signaling pathway and the glutamatergic synapse in the etiology of the disorder ENSG00000198793 ENSG00000179603 ENSG00000196712 PMC8904414__F1 Different Pattern of Cardiovascular Impairment in Methylmalonic Acidaemia Subtypes ENSG00000110395 ENSG00000142273 PMC9166238__F1 Review of ApoE4 Interference Targeting Mitophagy Molecular Pathways for Alzheimer's Disease ENSG00000198793 ENSG00000158828 ENSG00000112561 ENSG00000096717 PMC8331109__F8 Qilin Pill Exerts Therapeutic Effect on Resection-Induced Premature Ovarian Insufficiency Rats by Inhibiting the MAPK and PI3K-AKT Signaling Pathways ENSG00000157404 ENSG00000171105 ENSG00000135446 ENSG00000138798 ENSG00000128052 ENSG00000177606 ENSG00000173039 ENSG00000112715 ENSG00000146648 ENSG00000164305 PMC7139310__F1 PERK-Dependent Molecular Mechanisms as a Novel Therapeutic Target for Neurodegenerative Diseases ENSG00000128272 PMC7925768__F1 O-GlcNAcylation: the “stress and nutrition receptor” in cell stress response ENSG00000047410 ENSG00000198408 PMC7991810__F2 Signaling cascade of NC1-peptide that regulates spermatogenesis ENSG00000070831 ENSG00000198793 PMC8955086__F6 Chemistry, Biosynthesis and Pharmacology of Sarsasapogenin: A Potential Natural Steroid Molecule for New Drug Design, Development and Therapy ENSG00000278718 ENSG00000162711 ENSG00000091106 PMC9019367__F2 Research Progress of Epithelial-mesenchymal Transition Treatment and Drug Resistance in Colorectal Cancer ENSG00000134982 ENSG00000168036 PMC5098226__F1 Engineering of Escherichia coli for direct and modulated biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) copolymer using unrelated carbon sources ENSG00000087085 ENSG00000166278 PMC3920946__F1 Serine, one-carbon cycle, glycine synthesis (SOG) pathway ENSG00000228716 ENSG00000065911 ENSG00000163738 ENSG00000112992 ENSG00000145020 ENSG00000146733 ENSG00000164933 ENSG00000178445 ENSG00000120254 ENSG00000284320 ENSG00000100714 ENSG00000092621 ENSG00000145321 ENSG00000091140 PMC5242448__F1 Cell signaling transduction pathways controlled by WISP-1 in different cancer cells ENSG00000087245 ENSG00000148400 ENSG00000291971 ENSG00000100985 ENSG00000112715 ENSG00000146648 PMC4600536__F3 Role of IGF-I Signaling in Muscle Bone Interactions ENSG00000002330 ENSG00000198793 ENSG00000177606 PMC2966895__F2 Complement-targeted therapeutics ENSG00000203710 ENSG00000244731 ENSG00000166278 ENSG00000182326 ENSG00000236625 PMC6962593__F3 Toll like receptor 4 (TLR4)-dependent basal lung transcriptomics ENSG00000162772 ENSG00000109854 ENSG00000066583 ENSG00000119041 ENSG00000135720 ENSG00000172216 ENSG00000198924 ENSG00000186566 ENSG00000141279 ENSG00000181610 ENSG00000125538 ENSG00000092148 ENSG00000004961 ENSG00000174197 ENSG00000134644 ENSG00000100417 ENSG00000139278 ENSG00000154928 ENSG00000188994 ENSG00000163515 ENSG00000262406 ENSG00000109321 ENSG00000087074 ENSG00000172543 ENSG00000073756 ENSG00000168610 ENSG00000113905 ENSG00000118785 ENSG00000177606 ENSG00000100154 PMC9030821__F2 RNA-seq and Mitochondrial DNA Analysis of Adrenal Gland Metastatic Tissue in a Patient with Renal Cell Carcinoma ENSG00000145824 ENSG00000189377 ENSG00000169248 ENSG00000169245 ENSG00000186810 ENSG00000107562 ENSG00000081041 ENSG00000161921 ENSG00000163739 ENSG00000163734 ENSG00000124875 PMC11624815__F9 Mitochondrial metabolic reprogramming of macrophages and T cells enhances CD47 antibody-engineered oncolytic virus antitumor immunity PMC4455348__F1 Schematic of HER3 engagedment in heterodimerization and signaling ENSG00000284774 ENSG00000002330 ENSG00000198793 PMC6260778__F8 Effects of the metabolite, RA, on Tregs ENSG00000049768 PMC6260778__F6 Hypoxia induces differentiation of T-cells to Tregs ENSG00000198793 ENSG00000049768 PMC6260778__F7 Low pH induces differentiation of T cell into Tregs ENSG00000049768 ENSG00000168610 PMC6260778__F5 Microenvironment recruits Tregs to tumor tissue by chemotaxis ENSG00000151882 ENSG00000107562 ENSG00000184451 ENSG00000049768 ENSG00000121966 ENSG00000115009 ENSG00000112486 PMC7971890__F8 JMJD6 negatively regulates cytosolic RNA induced antiviral signaling by recruiting RNF5 to promote activated IRF3 K48 ubiquitination ENSG00000183735 ENSG00000088888 ENSG00000070495 ENSG00000131323 PMC6260778__F3 Effect of glycolysis on Tregs ENSG00000150907 ENSG00000136997 ENSG00000049768 PMC8657471__F2 EREG/EGFR Pathway in Tumor Progression ENSG00000041353 ENSG00000109321 ENSG00000291971 ENSG00000124882 ENSG00000198793 ENSG00000168610 ENSG00000146648 ENSG00000159399 PMC10281733__F10 LPS-antagonist potential of Q3G on pulmonary injury ENSG00000278718 ENSG00000162711 ENSG00000136869 PMC8657471__F3 EREG/EGFR Pathway in Tumor Progression ENSG00000019991 ENSG00000109321 ENSG00000124882 ENSG00000138798 ENSG00000146648 PMC6061846__F8 Signalling pathway that mediates TRPA1-dependent PMA induced by GTN ENSG00000104321 PMC8538727__F2 Nicotinamide Riboside for the Prevention and Treatment of Doxorubicin Cardiomyopathy. Opportunities and Prospects ENSG00000105835 ENSG00000278488 ENSG00000157064 ENSG00000173614 ENSG00000183077 PMC8657471__F4 EREG/EGFR Pathway in Tumor Progression ENSG00000041353 ENSG00000109321 ENSG00000124882 ENSG00000170558 ENSG00000168610 ENSG00000146648 PMC7352727__F7 KRAS promotes glycolysis, protein and lipid synthesis and one carbon pathway ENSG00000198793 PMC8657471__F5 EREG/EGFR Pathway in Tumor Progression ENSG00000157764 ENSG00000124882 ENSG00000146648 PMC9548442__F1 Lighting the way to host-directed immunotherapeutics ENSG00000167601 ENSG00000171855 ENSG00000183735 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000131323 ENSG00000276561 ENSG00000142166 PMC6905007__F2 LRF/ZBTB7A’s silencing compromises Warburg effect and induces apoptosis in cancer cells ENSG00000178951 ENSG00000067057 ENSG00000171791 ENSG00000078237 ENSG00000284194 ENSG00000026103 PMC7397197__F5 Nonautonomous replication stress response in the central nervous system ENSG00000183735 ENSG00000164430 ENSG00000163568 PMC7233810__F5 Apolipoprotein A-I anti-tumor activity targets cancer cell metabolism ENSG00000110921 ENSG00000132196 ENSG00000116133 ENSG00000143878 ENSG00000197429 ENSG00000113161 ENSG00000104549 ENSG00000167508 PMC5641881__F1 Metabolic reprogramming in cancer cells under hypoxia ENSG00000104812 ENSG00000087299 ENSG00000169710 ENSG00000115419 PMC6278507__F6 Molecules associated with ‘focal adhesion’ pathway ENSG00000169291 ENSG00000177606 PMC8047580__F1 An Integrated Approach of the Potential Underlying Molecular Mechanistic Paradigms of SARS-CoV-2-Mediated Coagulopathy ENSG00000130234 ENSG00000122194 PMC3044157__F6 The Nuclear Guanine Nucleotide Exchange Factors Ect2 and Net1 Regulate RhoB-Mediated Cell Death after DNA Damage ENSG00000114346 ENSG00000143878 PMC7430912__F5 KEGG pathway analyses of DESR genes expressed across multiple time points implicated the Adipocytokine signaling pathway as playing a prominent role in successful CNS axon regeneration ENSG00000198793 ENSG00000127191 ENSG00000168610 PMC8047580__F2 An Integrated Approach of the Potential Underlying Molecular Mechanistic Paradigms of SARS-CoV-2-Mediated Coagulopathy ENSG00000110799 ENSG00000162692 PMC8047580__F3 An Integrated Approach of the Potential Underlying Molecular Mechanistic Paradigms of SARS-CoV-2-Mediated Coagulopathy ENSG00000130234 ENSG00000198793 ENSG00000175104 ENSG00000122194 ENSG00000164342 PMC7991060__F1 Review of Prostanoid Receptors: Expression, Characterization, Regulation, and Mechanism of Action ENSG00000095303 ENSG00000148344 ENSG00000124212 ENSG00000073756 PMC6691376__F8 Schematic model for the positive feedback loop between fibroblast activation and ECM deposition mediated by CD44-RhoA-YAP signaling pathway ENSG00000026508 ENSG00000150457 ENSG00000131023 ENSG00000062485 PMC8283805__F2 Comparison of COVID-19 and Lung Cancer via Reactive Oxygen Species Signaling ENSG00000102034 ENSG00000138798 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC8772830__F1 Sirtuins and Sepsis: Cross Talk between Redox and Epigenetic Pathways ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000079999 PMC5072688__F5 Power-Law Modeling of Cancer Cell Fates Driven by Signaling Data to Reveal Drug Effects ENSG00000168610 ENSG00000146648 ENSG00000164305 PMC11244889__F8 T3SS triggered LTB4 synthesis differs between neutrophils and macrophages ENSG00000278718 ENSG00000162711 ENSG00000167323 PMC5833461__F7 EZH2 inhibits autophagic cell death of aortic vascular smooth muscle cells to affect aortic dissection ENSG00000057663 PMC6501765__F2 Leptin-a mediates transcription of genes that participate in central endocrine and phosphatidylinositol signaling pathways in 72-hour embryonic zebrafish (Danio rerio) ENSG00000152266 ENSG00000146469 ENSG00000183979 ENSG00000101180 ENSG00000110680 ENSG00000157017 ENSG00000135577 ENSG00000075073 ENSG00000010310 ENSG00000274473 ENSG00000183395 ENSG00000142538 ENSG00000162009 ENSG00000274247 ENSG00000096395 ENSG00000291972 ENSG00000165409 ENSG00000170893 ENSG00000198670 ENSG00000100739 PMC6501765__F3 Leptin-a mediates transcription of genes that participate in central endocrine and phosphatidylinositol signaling pathways in 72-hour embryonic zebrafish (Danio rerio) ENSG00000127080 PMC6497508__F2 Role of the classical and terminal complement pathways in cold agglutinin disease and target levels of complement inhibitors ENSG00000166278 PMC4478296__F2 Mitogen-activated protein kinase (MAPK) signalling pathway ENSG00000157404 ENSG00000198793 ENSG00000146648 PMC3625556__F7 The possible molecular mechanisms of pomegranate-mediated chemoprevention of experimental hepatocarcinogenesis in rats ENSG00000168036 PMC4107162__F1 Mechanisms of cellular invasion by intracellular parasites ENSG00000203710 PMC4702801__F1 Snapshot of Colorectal Cancer Atlas features ENSG00000213658 ENSG00000159335 PMC10970282__F8 Construction of the potential miRNA-target negative correlation regulatory network involved in the FoxO signaling pathway following G ENSG00000158022 PMC9523361__F5 Tuning Rex rules HTLV-1 pathogenesis ENSG00000111537 ENSG00000141086 PMC7159149__F6 Commonly dysregulated genes ENSG00000139193 ENSG00000134982 ENSG00000102871 ENSG00000138798 ENSG00000198793 ENSG00000130159 ENSG00000132693 ENSG00000168610 ENSG00000113905 ENSG00000226275 ENSG00000145192 ENSG00000112208 ENSG00000080823 ENSG00000112115 ENSG00000062485 PMC9496762__F2 Emerging Roles of TRIM Family Proteins in Gliomas Pathogenesis ENSG00000154370 ENSG00000132109 ENSG00000108395 ENSG00000166326 ENSG00000119401 ENSG00000198793 ENSG00000204977 ENSG00000173039 ENSG00000168036 ENSG00000171206 ENSG00000168610 ENSG00000132481 ENSG00000134253 ENSG00000122779 ENSG00000146648 ENSG00000292186 ENSG00000292195 ENSG00000130726 PMC5525000__F1 Schematic representation of sulfides (H2S) synthesis and oxidation pathways ENSG00000137767 PMC4211077__F2 Advances in understanding of bile acid diarrhea ENSG00000160867 PMC3774122__F2 NRF2-mediated oxidative stress response pathway ENSG00000163558 ENSG00000165280 PMC2937358__F1 ERAlpha-Negative and Triple Negative Breast Cancer: Molecular Features and Potential Therapeutic Approaches ENSG00000081041 ENSG00000163734 ENSG00000124875 ENSG00000146648 PMC10298409__F11 Integrated Transcriptomics and Metabolomics Analysis of the Fructan Metabolism Response to Low-Temperature Stress in Garlic PMC9685423__F1 Identification of unusual oxysterols biosynthesised in human pregnancy by charge-tagging and liquid chromatography - mass spectrometry ENSG00000124575 ENSG00000242110 ENSG00000083807 ENSG00000203857 ENSG00000135929 PMC7432057__F1 Mechanisms involved in the effects of adiponectin in different liver diseases including hepatic I/R ENSG00000148346 ENSG00000138207 ENSG00000288411 ENSG00000172936 ENSG00000136869 ENSG00000175567 ENSG00000096717 ENSG00000175104 ENSG00000168610 ENSG00000132693 ENSG00000026103 PMC7432057__F3 Adiponectin and leptin in the progression of nonalcoholic fatty liver disease (NAFLD) to hepatocellular carcinoma (HCC) ENSG00000198793 ENSG00000168610 PMC7408019__F6 KLF4 acts as a negative regulator of wt-CFTR but has its function disrupted in the F508del–CFTR cells ENSG00000151929 ENSG00000001626 ENSG00000136826 PMC6439804__F1 Hedgehog-Induced Osteogenesis ENSG00000178860 ENSG00000106571 ENSG00000128602 ENSG00000281857 PMC5343808__F1 Sonic Hedgehog Pathway: Shh acts on Ptch to inhibit the repression of Smo by Ptch ENSG00000136997 ENSG00000128602 PMC5343808__F2 Wnt Pathway: In the presence of Wnt ligands, Dsh blocks the Beta-catenin destruction complex consisting of Axin, APC, CK1, GSK3B ENSG00000137673 ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC6540809__F1 B cells mediate MS pathology through antibody-dependent and antibody-independent mechanisms ENSG00000226275 ENSG00000173599 PMC8371405__F2 Long Non-coding RNAs on Bladder Cancer ENSG00000164379 ENSG00000169554 ENSG00000088305 ENSG00000253352 PMC7059628__F8 Comparison between wild‐type and gas7‐knockout neurons of mitofusin regulation by the PINK1 and parkin‐mediated mitophagy pathway ENSG00000007237 ENSG00000116688 ENSG00000158828 ENSG00000171109 PMC8371405__F3 Long Non-coding RNAs on Bladder Cancer ENSG00000108691 ENSG00000138336 ENSG00000162924 ENSG00000205250 PMC2923369__F2 Auto-layout of ‘Caffeine (C) neighborhood’ based on Ingenuity curated finding (IPA, Ingenuity® Systems) PMC4548197__F1 Neuronal apoptosis network ENSG00000132906 ENSG00000002330 ENSG00000171791 ENSG00000164305 PMC6381369__F1 An illustrated view of Netrin-UNC5B signaling ENSG00000182175 ENSG00000130643 ENSG00000162551 ENSG00000164935 ENSG00000177606 ENSG00000007908 PMC5729908__F9 m6A mRNA methylation controls T cell homeostasis by targeting IL-7/STAT5/SOCS pathway ENSG00000105639 ENSG00000104432 ENSG00000165819 ENSG00000168685 PMC4323367__F7 Summary of radiation-induced persistent alterations of IGF1 and leptin signaling pathways observed in our study ENSG00000169047 ENSG00000140443 PMC8745001__F4 Cytosolic Quality Control of Mitochondrial Protein Precursors—The Early Stages of the Organelle Biogenesis ENSG00000284774 ENSG00000128272 ENSG00000144895 ENSG00000162600 ENSG00000169136 ENSG00000159459 PMC139865__F12 Innate immunity pathways in Drosophila ENSG00000077150 ENSG00000109320 ENSG00000162924 ENSG00000175104 PMC4101637__F10 Working hypothesis on the distinct mechanisms by which TNFA/IL-1B and IL-6 inhibit the hepatic GH-IGF-I pathway during inflammation ENSG00000112964 ENSG00000125538 PMC10215516__F2 PI3K/AKT/mTOR signaling pathway activation in HPV-positive HNCs ENSG00000198793 ENSG00000124107 PMC4258093__F3 Canonical Wnt signaling ENSG00000134982 ENSG00000168036 PMC4030405__F1 Complement system ENSG00000039537 ENSG00000113600 ENSG00000288512 ENSG00000166278 ENSG00000182326 PMC8847026__F12 “Weird” Mitochondrial Fatty Acid Oxidation as a Metabolic “Secret” of Cancer ENSG00000157184 ENSG00000131473 ENSG00000173599 ENSG00000079432 ENSG00000112992 PMC5903427__F1 Purine salvage pathway and HGprt function () ENSG00000196839 ENSG00000291814 PMC4258093__F1 PI3K signaling ENSG00000169047 ENSG00000198793 ENSG00000164327 PMC8509287__F2 Host–Viral Interactions in the Pathogenesis of Ulcerative Colitis ENSG00000088888 ENSG00000172936 PMC3770093__F1 Sphingolipid biosynthetic pathway ENSG00000069482 ENSG00000070610 PMC6111072__F10 Schematic Diagram Illustrates and Summarizes the Role and Signaling Pathway of PAK1 in Regulating Human SSCsPAK1 is mediated by EGF, but not by GDNF or FGF2; PDK1, ZNF367, and KDR are the targets of PAK1 ENSG00000149269 ENSG00000138798 ENSG00000128052 ENSG00000165244 ENSG00000146648 PMC8207884__F4 Correlation Between the Evolution of Somatic Alterations During Lymphatic Metastasis and Clinical Outcome in Penile Squamous Cell Carcinoma ENSG00000149311 ENSG00000157404 ENSG00000142192 ENSG00000167941 ENSG00000123572 ENSG00000198793 ENSG00000164327 PMC10486691__F6 Association of EN2 with ERBB, insulin, BCR-ABL and JAK signaling ENSG00000033327 ENSG00000002330 ENSG00000198793 ENSG00000137193 ENSG00000131095 ENSG00000099942 ENSG00000196396 ENSG00000168610 ENSG00000138378 ENSG00000107263 ENSG00000110395 ENSG00000115415 ENSG00000177606 ENSG00000136997 PMC7397749__F1 Synthesis and metabolism of PUFAs ENSG00000134824 ENSG00000149485 ENSG00000173599 ENSG00000111684 ENSG00000197977 ENSG00000198670 ENSG00000273592 ENSG00000281857 PMC7500861__F5 Metabolic pathway differences between LLO118 and LLO56 and identification of mGPD2 as a candidate gene ENSG00000117118 ENSG00000213614 ENSG00000169710 ENSG00000135069 ENSG00000130653 ENSG00000095380 ENSG00000128050 ENSG00000292096 ENSG00000111726 ENSG00000131238 ENSG00000143149 ENSG00000092621 ENSG00000108474 ENSG00000125772 ENSG00000291994 ENSG00000143179 ENSG00000124181 ENSG00000091140 ENSG00000125166 ENSG00000067057 ENSG00000064225 ENSG00000108515 ENSG00000105223 ENSG00000115361 ENSG00000152952 ENSG00000171608 ENSG00000168237 ENSG00000082212 ENSG00000159399 ENSG00000084774 PMC7761926__F1 General view of canonical and non-canonical Wnt signaling ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000070831 ENSG00000100592 ENSG00000134982 ENSG00000177606 ENSG00000183579 ENSG00000185483 ENSG00000168036 ENSG00000108375 PMC7736362__F1 Rewiring yeast metabolism to synthesize products beyond ethanol ENSG00000122966 PMC5612418__F3 Neuroprotective actions of perinatal choline nutrition ENSG00000151224 ENSG00000016391 ENSG00000116984 PMC3467082__F1 Translation of glutamine codons in yeast ENSG00000145321 ENSG00000137831 PMC6415285__F2 Statins on several pathways involved in bone metabolism ENSG00000108691 PMC11979612__F12 Aconiti Lateralis Radix Praeparata ameliorates heart failure via PI3K/AKT/Bnip3 pathway ENSG00000057663 PMC7761926__F2 Wnt targeting agents for the Wnt/Beta-catenin signaling pathway ENSG00000156076 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000147869 ENSG00000102312 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000154310 ENSG00000185269 ENSG00000173273 PMC9619093__F2 Joint together: The etiology and pathogenesis of ankylosing spondylitis ENSG00000159216 ENSG00000136869 ENSG00000168610 ENSG00000162892 PMC7158891__F3 An integrated overview of the immunosuppressive signaling pathways involved in the interaction between exosomal PD-L1 and T cells ENSG00000291603 ENSG00000118898 PMC8875594__F1 PCSK9 Promotes Cardiovascular Diseases: Recent Evidence about Its Association with Platelet Activation-Induced Myocardial Infarction ENSG00000115008 ENSG00000135218 ENSG00000130164 ENSG00000291971 ENSG00000169174 PMC4707198__F5 Schematic illustration of Hog1-mediated posttranslational and transcriptional hyperosmotic stress response pathway PMC1479092__F1 The mitochondrial generated ROS-mediated activation of the p38 MAPK stress response pathway ENSG00000177606 ENSG00000123268 PMC2892298__F8 Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors ENSG00000177732 ENSG00000176887 ENSG00000124766 ENSG00000074219 PMC7849354__F2 Pseudomonas aeruginosa as a Model To Study Chemosensory Pathway Signaling ENSG00000057593 PMC7849354__F3 Pseudomonas aeruginosa as a Model To Study Chemosensory Pathway Signaling ENSG00000057593 ENSG00000206177 PMC4748038__F2 Shigella exploits Ca2+signaling to delay cell death and to dampen inflammation ENSG00000196954 ENSG00000116717 ENSG00000106100 ENSG00000164305 PMC3296768__F5 Targeting Bone Remodeling by Isoflavone and 3,3′-Diindolylmethane in the Context of Prostate Cancer Bone Metastasis ENSG00000157933 ENSG00000125255 PMC6580952__F1 Salient features of EBV latent transcripts during B-cell transformation, followed by B-cell lymphoma development ENSG00000175054 ENSG00000102871 ENSG00000186716 ENSG00000144848 ENSG00000137193 ENSG00000137265 ENSG00000123374 ENSG00000196092 ENSG00000105810 ENSG00000171791 ENSG00000118971 ENSG00000057663 PMC7443136__F8 TLR4 promotes microglial pyroptosis via lncRNA-F630028O10Rik by activating PI3K/AKT pathway after spinal cord injury ENSG00000278718 ENSG00000162711 ENSG00000172936 ENSG00000136869 ENSG00000108821 PMC2586899__F4 The involvement of TNFAlpha-mediated signaling pathways in insulin resistance ENSG00000169047 ENSG00000198793 PMC7927199__F9 Proposed schematic model summarizing the role of GNL1 as an antiapoptotic protein ENSG00000171791 PMC3324360__F5 Simplified TGFB pathway ENSG00000095739 ENSG00000162772 ENSG00000125968 PMC7554781__F2 Glial cell line-derived neurotrophic factor family ligands (GFLs) signaling ENSG00000291971 ENSG00000010810 ENSG00000171119 ENSG00000117407 ENSG00000130513 ENSG00000125650 PMC4064060__F4 Molecular interactions between Wnt/Beta-catenin and PPARG signaling in colorectal cancer cells ENSG00000134982 ENSG00000168036 PMC9438157__F9 M6A demethylase ALKBH5-mediated upregulation of DDIT4-AS1 maintains pancreatic cancer stemness and suppresses chemosensitivity by activating the mTOR pathway ENSG00000198952 ENSG00000168209 ENSG00000198793 ENSG00000091542 ENSG00000164949 PMC9370682__SF1 Design, Synthesis and Biological Evaluation of [1,2,4]Triazolo[1,5-a]pyrimidine Indole Derivatives against Gastric Cancer Cells MGC-803 via the Suppression of ERK Signaling Pathway ENSG00000187475 ENSG00000189060 ENSG00000124575 ENSG00000178804 ENSG00000124610 ENSG00000184357 ENSG00000187837 PMC12234474__F5 Targeted Therapeutic Strategies for PDAC ENSG00000198793 PMC4402390__F6 Metabolic network of CcsR-dependent targets and influence on cell regulatory networks ENSG00000179091 PMC8438693__F3 Protein phosphatase 2A in kidney disease (Review) ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC4064060__F1 The Wnt/Beta-catenin signaling in epithelial cells ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000026508 ENSG00000168036 ENSG00000132478 PMC6614411__F4 Pathway-based analysis for glycolysis, TCA cycle and pentose phosphate pathway ENSG00000144063 ENSG00000149311 ENSG00000110711 ENSG00000197713 ENSG00000172005 ENSG00000096088 PMC9170957__F2 From Therapy Resistance to Targeted Therapies in Prostate Cancer ENSG00000291971 ENSG00000146648 PMC1236698__F2 Molecular mechanisms of autophagy ENSG00000124102 ENSG00000152348 ENSG00000126775 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC6071982__F4 Parental high dietary arachidonic acid levels modulated the hepatic transcriptome of adult zebrafish (Danio rerio) progeny ENSG00000073060 ENSG00000161533 ENSG00000169710 ENSG00000130589 ENSG00000134780 PMC5479302__F8 Proposed signaling pathway activated by CTS in CCA cells.Notes: The potential mechanism of apoptosis induced by CTS in HCCC-9810 and RBE cells ENSG00000168610 PMC9370780__F11 Cornuside Is a Potential Agent against Alzheimer’s Disease via Orchestration of Reactive Astrocytes ENSG00000170458 ENSG00000131095 ENSG00000139211 ENSG00000102003 ENSG00000285348 ENSG00000137801 PMC12128267__F9 Proposed mechanism of gastrointestinal exposure to SiO2 NPs induced AD-like neurotoxicity ENSG00000171720 ENSG00000214285 PMC2743935__F5 Calcium signalling and cell-fate choice in B cells ENSG00000084093 ENSG00000070985 PMC10556522__F2 Genomic rearrangements that contribute to pathogenesis of ALK- ALCL () represents ALK- ALCL harboring DUSP22-rearrangement and associated signaling pathways ENSG00000123685 ENSG00000116815 ENSG00000077150 ENSG00000136997 ENSG00000137265 ENSG00000196498 ENSG00000047936 ENSG00000167522 ENSG00000178568 ENSG00000177565 PMC6071982__F5 Parental high dietary arachidonic acid levels modulated the hepatic transcriptome of adult zebrafish (Danio rerio) progeny ENSG00000178814 ENSG00000285250 ENSG00000116761 ENSG00000116984 PMC6744711__F2 Cross-talk between DNA damage and immune response ENSG00000149311 ENSG00000175054 ENSG00000164430 ENSG00000125347 PMC8450340__F8 Qiangjing Tablets Regulate Apoptosis and Oxidative Stress via Keap/Nrf2 Pathway to Improve the Reproductive Function in Asthenospermia Rats ENSG00000178573 ENSG00000100387 ENSG00000177606 ENSG00000079999 PMC6591470__F2 Schematic illustration of the cell type-specific effects of impaired PI3K-Akt signaling in AD brain ENSG00000115008 ENSG00000198793 PMC7151139__F1 BMP signaling pathway ENSG00000170365 ENSG00000137834 PMC9113095__F8 Genetic evidence for the requirements of antroquinonol biosynthesis by Antrodia camphorata during liquid-state fermentation ENSG00000132423 ENSG00000110871 ENSG00000173085 PMC10556522__F1 Pathogenic signaling pathways in ALK+ ALCL () represents deregulated T-cell receptor signaling pathways mediated by NPM::ALK ENSG00000131473 ENSG00000138795 ENSG00000002330 ENSG00000099985 ENSG00000198793 ENSG00000196591 ENSG00000168610 ENSG00000162594 ENSG00000112116 ENSG00000145839 ENSG00000117091 ENSG00000115415 ENSG00000122223 ENSG00000113318 ENSG00000010810 ENSG00000104549 ENSG00000113520 ENSG00000107485 ENSG00000113263 ENSG00000104432 ENSG00000095002 PMC6591470__F1 Schematic presentation of PI3K-Akt intracellular signaling PMC8280023__F3 Gut Microbial Metabolites in Parkinson’s Disease: Implications of Mitochondrial Dysfunction in the Pathogenesis and Treatment ENSG00000171109 ENSG00000214253 PMC5845444__F2 13C metabolic flux analysis of E ENSG00000122966 ENSG00000166863 ENSG00000172005 ENSG00000150787 PMC2933224__F1 Gradient Descent Optimization in Gene Regulatory Pathways ENSG00000132906 ENSG00000102871 ENSG00000138794 ENSG00000196954 ENSG00000168040 ENSG00000164305 ENSG00000026103 PMC8945569__F2 Klotho an Autophagy Stimulator as a Potential Therapeutic Target for Alzheimer’s Disease: A Review ENSG00000162711 ENSG00000125538 PMC6467375__F5 PID1 alters the antilipolytic action of insulin and increases lipolysis via inhibition of AKT/PKA pathway activation ENSG00000042832 PMC4586249__F3 RecQ helicases in base excision repair (BER) and double-strand break repair (DSBR) ENSG00000143799 ENSG00000115008 ENSG00000138346 ENSG00000039650 ENSG00000105486 ENSG00000132646 ENSG00000165392 ENSG00000175643 ENSG00000197299 ENSG00000137074 ENSG00000178966 ENSG00000051180 ENSG00000140398 ENSG00000177084 ENSG00000042088 PMC2562925__F8 Schematic depicting the roles of p53 and wnt7b in proposed pathway for NGF-mediated neurite outgrowth in PC12 differentiation ENSG00000188064 ENSG00000188763 ENSG00000155760 PMC7985079__F1 Modified model of the HMA-induced viral mimicry in leukemic cells ENSG00000213928 ENSG00000088888 ENSG00000135828 ENSG00000276561 PMC4266699__F1 HER family and EGFR signaling pathway ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC7397772__F1 Apolipoprotein E (APOE) exhibits both proinflammatory and antiinflammatory properties ENSG00000162711 ENSG00000130164 ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC4475926__F9 COX-2 increases insulin signaling by downregulation of miR-183 ENSG00000169047 ENSG00000108654 ENSG00000128191 ENSG00000113360 PMC10874461__F5 Pathological mechanisms of osteoporosis induced by diabetes, glucocorticoids, and psychological stress ENSG00000178860 ENSG00000152266 ENSG00000159224 ENSG00000291972 ENSG00000115457 ENSG00000167941 ENSG00000145321 ENSG00000168036 PMC10874461__F2 X-linked osteoporosis in males ENSG00000281324 ENSG00000162337 ENSG00000110799 ENSG00000134982 ENSG00000168036 PMC5776968__F5 Signaling pathway responding to oligodeoxynucleotides of class C ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000163568 ENSG00000186716 ENSG00000125538 ENSG00000172936 ENSG00000276561 ENSG00000010671 PMC6636046__F7 Enriched KEGG pathways generated by ClueGO and Cluepedia ENSG00000164430 ENSG00000164161 ENSG00000109321 ENSG00000153982 ENSG00000168036 ENSG00000135828 ENSG00000070214 ENSG00000146648 ENSG00000087460 ENSG00000143924 ENSG00000132170 ENSG00000186469 PMC4751379__F8 Ingenuity pathway analysis of GH signaling after hepatectomy ENSG00000274211 ENSG00000245848 ENSG00000120833 ENSG00000115415 ENSG00000169047 ENSG00000175899 ENSG00000180008 ENSG00000168610 PMC9014242__F8 Signaling Pathways That Mediate Alveolar Macrophage Activation by Surfactant Protein A and IL-4 ENSG00000008710 ENSG00000105639 PMC4706435__F6 MiR-124 Promote Neurogenic Transdifferentiation of Adipose Derived Mesenchymal Stromal Cells Partly through RhoA/ROCK1, but Not ROCK2 Signaling Pathway ENSG00000185591 ENSG00000067900 PMC4499589__F7 EphA2 Receptor Signaling Mediates Inflammatory Responses in Lipopolysaccharide-Induced Lung Injury ENSG00000142627 ENSG00000125538 ENSG00000136869 PMC3141988__F6 An E-cadherin–mediated Hippo signaling pathway ENSG00000150457 ENSG00000131023 PMC8686226__F3 Developing landscape of combinatorial therapies of immune checkpoint blockade with DNA damage repair inhibitors for the treatment of breast and ovarian cancers ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000183735 ENSG00000164430 ENSG00000111537 ENSG00000163599 PMC9272524__F3 Role and Therapeutic Perspectives of Sirtuin 3 in Cancer Metabolism Reprogramming, Metastasis, and Chemoresistance ENSG00000147649 ENSG00000100412 ENSG00000142082 PMC4083693__F1 Wnt signaling is required for long-term memory formation ENSG00000134982 ENSG00000170558 ENSG00000168036 ENSG00000167074 PMC4292235__F1 Assembly and mechanism of action of CpG ODN/Tat nanorings ENSG00000239732 ENSG00000111537 ENSG00000172936 PMC3306972__F1 ABPP processing, the adaptor proteins interacting with its intracellular domain and the pathway leading to ERK1/2 activation ENSG00000142192 ENSG00000133961 PMC9204553__F4 CTRP9 overexpression attenuates palmitic acid-induced inflammation, apoptosis and impaired migration in HTR8/SVneo cells through AMPK/SREBP1c signaling ENSG00000180210 ENSG00000135218 ENSG00000001626 ENSG00000026103 PMC5685850__F4 Wnt receptor signaling pathway and regulation of Rab GTPase activity involved in miRNA expression ENSG00000166167 ENSG00000178585 ENSG00000005339 ENSG00000181274 ENSG00000104946 ENSG00000050748 ENSG00000173218 ENSG00000167291 ENSG00000189375 ENSG00000165059 ENSG00000168036 ENSG00000104332 ENSG00000161202 PMC11641400__F3 HA35 enriches signaling pathways involved in growth and antioxidant response in the developing murine intestine ENSG00000144744 ENSG00000198793 ENSG00000184182 ENSG00000116030 ENSG00000119048 PMC5664070__F3 An overview of signaling cascades involved in PLK1-induced EMT ENSG00000169554 ENSG00000166851 PMC6687767__F1 Natriuretic peptide signaling in adipose tissue ENSG00000145321 ENSG00000214285 PMC8620858__F1 Hypoxia: The Cornerstone of Glioblastoma ENSG00000134086 ENSG00000148400 ENSG00000100387 ENSG00000198793 ENSG00000154582 ENSG00000163960 PMC5014572__F3 Roles of MAS-related G protein coupled receptor-X2 (MRGPRX2) on mast cell-mediated host defense, pseudoallergic drug reactions and chronic inflammatory diseases ENSG00000183695 ENSG00000293604 ENSG00000197971 ENSG00000214285 PMC12121061__F8 Schematic model illustrating the mechanism of combined treatment of VEN and C-82 ENSG00000168036 ENSG00000164305 PMC9150122__F1 Biophysical Survey of Small-Molecule Beta-Catenin Inhibitors: A Cautionary Tale ENSG00000281324 ENSG00000137673 ENSG00000162337 ENSG00000168036 PMC3890705__F6 Proangiogenic mechanisms activated in the omentum during transcoelomic EOC metastasis in the presence of anti-VEGF therapy ENSG00000019991 ENSG00000161921 ENSG00000115457 ENSG00000163453 ENSG00000100985 ENSG00000112715 ENSG00000163737 PMC8622675__F2 Mechanosensing and the Hippo Pathway in Microglia: A Potential Link to Alzheimer’s Disease Pathogenesis? ENSG00000291971 ENSG00000150457 ENSG00000131023 PMC8371277__F2 Lipid droplets and lipid mediators in viral infection and immunity ENSG00000042832 PMC3071916__F2 Insights into the Pathogenesis and Treatment of Cancer from Inborn Errors of Metabolism PMC7139621__F1 Therapies fighting breast cancer through the fibroblast growth factor receptor (FGFR) pathway ENSG00000135446 ENSG00000198793 ENSG00000163661 PMC5983188__F1 Cytokine/long noncoding RNA (lncRNA) interplay in controlling immune cell development and function ENSG00000169429 ENSG00000073756 PMC4581295__F2 Signal pathways of chondrocyte hypertrophy ENSG00000170365 ENSG00000125398 ENSG00000134982 ENSG00000168036 ENSG00000163501 PMC6509841__F7 DEGs relevant to the “protein processing in endoplasmic reticulum” pathway under group “D vs ENSG00000128272 ENSG00000150991 ENSG00000144895 ENSG00000113558 ENSG00000188404 ENSG00000198168 PMC3064560__F3 Analogue 3 also showed potent antiproliferative activity against the highly invasive non-small-cell lung cancer cell line CL1-5 with an ED50 value of 0.11 μM ENSG00000086827 ENSG00000132341 PMC11083511__F1 Subsets and functions of CD4+ T cells ENSG00000137265 ENSG00000107485 ENSG00000049768 ENSG00000106546 PMC5715135__F7 Canonical pathway of molecular mechanisms of cancer from IPA showing dysregulated mRNA targets along with their potential differentially expressed miRNA regulators found in Lebanese samples ENSG00000175054 ENSG00000138795 ENSG00000002330 ENSG00000136997 ENSG00000132478 ENSG00000111816 ENSG00000080839 ENSG00000125084 PMC8393536__F1 Myostatin/Activin-A Signaling in the Vessel Wall and Vascular Calcification ENSG00000241186 PMC8303169__F2 Pivotal Player: Components of NFKB Pathway as Promising Biomarkers in Colorectal Cancer ENSG00000104856 ENSG00000173039 PMC12237497__F10 Working model of GPR120 modulation of mammary gland function ENSG00000145824 ENSG00000135218 ENSG00000169710 ENSG00000136869 ENSG00000175104 ENSG00000121966 ENSG00000102974 PMC8303169__F3 Pivotal Player: Components of NFKB Pathway as Promising Biomarkers in Colorectal Cancer ENSG00000168610 ENSG00000146648 PMC10512452__F6 IL-10 Exerts anti-inflammatory effects through STAT3 signaling pathway ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC10558228__F1 NFKB signaling pathway and targets of inhibitors against neuroinflammation in AD ENSG00000170458 ENSG00000159346 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC6727029__F2 Pre-synaptic and post-synaptic mechanisms regulated by PPT1 ENSG00000131238 ENSG00000010810 ENSG00000220205 ENSG00000132639 PMC10558228__F3 NLRP3 signaling pathway and targets of inhibitors against neuroinflammation in AD ENSG00000278718 ENSG00000162711 ENSG00000136869 PMC10558228__F4 PPAR, STAT3 and PI3K/Akt signaling pathways and targets of inhibitors against neuroinflammation in AD ENSG00000168610 PMC10558228__F5 Targeting inflammatory signaling pathways with drugs shows promise in AD treatment ENSG00000162711 ENSG00000039537 ENSG00000142192 ENSG00000168610 PMC11908107__F8 LXR-alpha agonist is involved in various biological functions in liver transplants ENSG00000198793 PMC7264106__F1 TNFR1 and TNFR2 signaling pathway ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 PMC4201175__F1 Biochemical and genetic processes in malignant mesothelioma ENSG00000163930 ENSG00000186575 PMC6466115__F1 Biosynthesis pathway of histo-blood group antigens (HBGAs) by stepwise addition of monosaccharides to precursor structures ENSG00000179163 PMC5499698__F1 mTOR-signaling pathway: mTORC1 and mTORC2 complexes and the key signaling nodes that regulate mTORC1 and mTORC2 ENSG00000101407 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC7230684__F1 Folate metabolic pathway disrupted by methotrexate (MTX) ENSG00000228716 ENSG00000173638 PMC5499698__F3 Alterations in mTOR signaling pathway on spermatogenesis PMC7286861__F6 The PGD2–GPR44 axis in human islets exposed to hyperglycaemia and proinflammatory cytokines ENSG00000150907 ENSG00000139515 ENSG00000182759 PMC8820546__F2 AMPK/mTOR Signaling Pathway in Anticancer Activity of Metformin ENSG00000149311 PMC5454408__F2 HBV modulation of innate immune sensors ENSG00000174125 ENSG00000239732 ENSG00000088888 ENSG00000163568 ENSG00000172936 ENSG00000132478 ENSG00000107201 ENSG00000150455 ENSG00000164342 PMC3254670__F1 Metabolic connections during apoptotic cell engulfment ENSG00000167601 ENSG00000173369 ENSG00000153208 ENSG00000135218 ENSG00000140545 ENSG00000175567 PMC8578102__F1 Transforming Growth FactorB and the Renin-Angiotensin System in Syndromic Thoracic Aortic Aneurysms: Implications for Treatment ENSG00000137834 ENSG00000157933 ENSG00000122691 PMC6220063__F1 Eicosanoid biosynthesis and PGE2 signaling via EP receptors PMC4600637__F1 Altered expression of CDC42 signaling pathway components in cortical layer 3 pyramidal cells in schizophrenia ENSG00000106683 ENSG00000163171 ENSG00000070831 ENSG00000149269 ENSG00000182541 PMC6554373__GA Venlafaxine Mitigates Depressive-Like Behavior in Ovariectomized Rats by Activating the EPO/EPOR/JAK2 Signaling Pathway and Increasing the Serum Estradiol Level ENSG00000171791 ENSG00000127948 PMC10374743__F2 Warburg effect: a score for many instruments in the concert of cancer and cancer niche cells ENSG00000159399 PMC8581319__F1 Epithelial‐Mesenchymal Transition in colorectal cancer: Annexin A2 is caught in the crosshairs ENSG00000182718 ENSG00000019991 ENSG00000291971 ENSG00000138798 ENSG00000168610 PMC8086286__F2 Expression and regulatory roles of lncRNAs in G-CIMP-low vs G-CIMP-high Glioma: an in-silico analysis ENSG00000142627 ENSG00000105327 ENSG00000148400 ENSG00000099860 ENSG00000184481 ENSG00000168283 ENSG00000100290 ENSG00000124216 ENSG00000177595 ENSG00000066336 ENSG00000197576 ENSG00000156299 ENSG00000138166 ENSG00000164615 ENSG00000105991 ENSG00000136997 PMC6873590__F1 Glycolysis and biosynthetic pathways emanating from glycolysis ENSG00000284320 ENSG00000065911 ENSG00000100714 ENSG00000163738 ENSG00000146733 ENSG00000178445 PMC7253636__F1 Human pathway of assembly of lipoyl moieties on its cognate proteins ENSG00000121897 ENSG00000144182 ENSG00000291958 ENSG00000175536 PMC6328441__F4 Mechanism of CHOP regulation in ER stress induced apoptosis ENSG00000128272 ENSG00000144895 ENSG00000132478 ENSG00000162772 ENSG00000127191 PMC3654194__F1 Spatial and temporal organization of ubiquitin networks ENSG00000102871 ENSG00000172936 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC6328441__F1 Upstream regulatory pathway of CHOP ENSG00000128272 ENSG00000144895 PMC3504431__F1 MTOR pathway ENSG00000177169 ENSG00000106070 ENSG00000169047 ENSG00000155792 PMC7779329__F3 SARS-CoV-2 and relevant biological processes that involve ACE, PGR, FXIIIB, and tPA ENSG00000082175 ENSG00000130234 ENSG00000184012 ENSG00000122194 PMC4889230__F1 The stress-triggered signaling pathway leading to DNA damage and cell death ENSG00000086991 ENSG00000085871 PMC4967197__F5 Peroxisome proliferator-activated receptor (PPAR)-related fasting response in heart ENSG00000109819 ENSG00000274619 ENSG00000108582 ENSG00000138029 ENSG00000132170 PMC7215285__F3 Metabolic pathways including glycolysis, pentose phosphate pathway, tricarboxylic acid cycle, and lipid synthesis with target non-coding RNAs ENSG00000131473 ENSG00000159399 PMC4655822__F3 Establishment and Dysfunction of the Blood-Brain Barrier ENSG00000170558 PMC11678534__F2 Creatine in the promotion of cancer malignancy ENSG00000177606 ENSG00000159399 PMC7039327__F2 B-cell receptor signaling triggers formation of a multicomponent “signalosome,” which can activate BTK, AKT, PI3K, PLCG2, and BLNK, and CD19, a coreceptor important for PI3K activation ENSG00000177455 ENSG00000095585 ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000197943 ENSG00000010671 PMC9080378__F7 Genomic Understanding Reveals the Important Role of FGFR2 as Paeoniflorin Target for Circumventing Breast Cancer Resistance to Tamoxifen ENSG00000066468 ENSG00000125398 ENSG00000171791 PMC3753040__F1 Chromatin Recruitment of DNA repair proteins: Lessons from the Fanconi Anemia and Double Strand Break Repair Pathways ENSG00000012048 ENSG00000175054 ENSG00000144554 ENSG00000181544 ENSG00000187790 ENSG00000115392 ENSG00000162607 ENSG00000187741 ENSG00000112039 ENSG00000158169 ENSG00000139618 PMC6450717__F7 Loss of CHP1 rewires glycerolipid metabolism in proliferating cells ENSG00000042832 ENSG00000187446 ENSG00000173599 ENSG00000158669 ENSG00000117528 ENSG00000198670 ENSG00000116906 PMC3880903__F8 Fasting Induces Nuclear Factor E2-Related Factor 2 and ATP-Binding Cassette Transporters via Protein Kinase A and Sirtuin-1 in Mouse and Human ENSG00000023839 PMC9403138__F3 Microbiota-derived short-chain fatty acids: Implications for cardiovascular and metabolic disease ENSG00000163464 ENSG00000162711 ENSG00000168329 ENSG00000108691 ENSG00000121807 PMC9332593__F2 DNA Damage Response Regulation by Histone Ubiquitination ENSG00000012048 ENSG00000163961 ENSG00000112130 PMC8131681__F2 Smad Dependent TGFB and BMP Signaling Pathway in Bone Remodeling and Therapies ENSG00000131323 ENSG00000175104 ENSG00000131196 PMC11647263__F6 In SAE, Nogo-A plays a critical role through a series of complex signaling pathways ENSG00000162711 PMC8131681__F1 Smad Dependent TGFB and BMP Signaling Pathway in Bone Remodeling and Therapies ENSG00000170365 ENSG00000137834 PMC7469280__F2 TRAF6 mediates signaling transduction pathway ENSG00000002330 ENSG00000172936 ENSG00000130159 ENSG00000175104 PMC7469280__F3 TRAF6 regulates tumor related to signaling transduction pathways ENSG00000162337 ENSG00000168036 ENSG00000130159 ENSG00000100985 ENSG00000175104 PMC9563021__F7 Baicalin Modulates Inflammatory Response of Macrophages Activated by LPS via Calcium-CHOP Pathway ENSG00000115415 ENSG00000073756 ENSG00000007171 ENSG00000026103 PMC4759477__F3 Platycodin D‐induced G2/M phase cell cycle arrest in cancer cells ENSG00000134057 PMC6290461__F2 Shared molecular and cellular mechanisms of premature ageing and ageing-associated diseases ENSG00000143799 ENSG00000132646 ENSG00000051180 PMC6290461__F1 Shared molecular and cellular mechanisms of premature ageing and ageing-associated diseases ENSG00000198793 ENSG00000084073 PMC3926427__F4A Targeting Fibroblast Growth Factor Pathways in Prostate Cancer ENSG00000070193 ENSG00000102678 ENSG00000077782 PMC9553876__F1 Molecular pathway changes caused by TTFields on glioma, GBM, MPM, NSCLC, and breast cancer Fig. 1A, Gliomas and glioblastomas ENSG00000012048 ENSG00000164430 ENSG00000163568 ENSG00000198793 PMC7929421__F2 Unfolded protein response pathway ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000171791 ENSG00000127191 PMC9553876__F2 Molecular pathway changes caused by TTFields combined with radiotherapy or drugs in GBM, MPM, NSCLC, and breast cancer ENSG00000012048 ENSG00000144554 ENSG00000177606 ENSG00000187741 ENSG00000168610 PMC7929421__F3 Immune response activation pathway ENSG00000183735 ENSG00000086991 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000175104 ENSG00000276561 PMC12111645__F7 THC-induced neurotoxicity Via MCU ENSG00000156026 ENSG00000125648 ENSG00000148339 PMC8148118__F3 Multifaceted Role of AMPK in Viral Infections ENSG00000177169 ENSG00000042832 ENSG00000150907 ENSG00000061273 ENSG00000113161 ENSG00000112561 ENSG00000265972 ENSG00000108840 PMC12006087__F4 KEGG pathway analysis ENSG00000135446 ENSG00000113263 PMC6196273__F2 Iron chelators modulate multiple immunometabolic pathways via the stabilization of HIF1A ENSG00000111537 ENSG00000125538 ENSG00000026103 PMC10733979__F1 Key cellular metabolic pathways in which NAD(P)H and FAD are involved, including glycolysis, the TCA cycle, oxidative phosphorylation, fatty acid oxidation and synthesis, and the glutathione pathway ENSG00000112992 ENSG00000105227 PMC8989428__F3 Molecular pathways associated with oxidative stress and their potential applications in radiotherapy (Review) ENSG00000168003 ENSG00000128272 ENSG00000151012 ENSG00000167468 PMC4067916__F1 The Hippo pathway in mammals ENSG00000109321 ENSG00000139926 ENSG00000150457 ENSG00000131023 PMC5802554__F1 Mutational heterogeneity of angioimmunoblastic T-cell lymphoma indicates distinct lymphomagenic pathways ENSG00000141968 PMC7577509__F1 Clinical implications of biomarker interactions in CRC ENSG00000124102 ENSG00000157764 PMC2529314__F8 Over-representation of Toll-like receptor signaling pathway genes PMC4527365__F2 Activation and downstream signaling of class III RTKs ENSG00000182578 ENSG00000122025 PMC10967848__F1 Representation of metabolic pathways of lipoprotein ENSG00000130164 ENSG00000138823 ENSG00000100979 PMC9152215__F4 Network Pharmacology and Experimental Verification Strategies to Illustrate the Mechanism of Jian-Pi-Yi-Shen Formula in Suppressing Epithelial–Mesenchymal Transition ENSG00000157766 ENSG00000124795 ENSG00000166169 PMC2529314__F7 Interactions of KEGG pathways for differentially expressed genes in different stages of PAD ENSG00000142192 ENSG00000186716 PMC5361678__F6 Resveratrol fuels HER2 and ERAlpha-positive breast cancer behaving as proteasome inhibitor ENSG00000291971 ENSG00000198793 ENSG00000155792 ENSG00000164327 PMC4818883__F2 Frequently mutated genes in ErbB signaling pathway ENSG00000169291 ENSG00000002330 ENSG00000113070 ENSG00000198793 ENSG00000177606 ENSG00000111816 ENSG00000169752 PMC8516279__F7 Signal and interaction networks of CD36 ENSG00000162711 ENSG00000135218 ENSG00000291971 ENSG00000168036 ENSG00000265972 ENSG00000182759 ENSG00000100979 ENSG00000285482 ENSG00000140284 ENSG00000136869 ENSG00000172171 ENSG00000163145 ENSG00000154719 ENSG00000136011 ENSG00000135482 ENSG00000154589 ENSG00000169344 ENSG00000005339 ENSG00000010327 ENSG00000050628 ENSG00000198561 ENSG00000163755 ENSG00000132170 ENSG00000170458 ENSG00000107854 PMC4189793__F1 Involvement of Tumor Macrophage HIFs in Chemotherapy Effectiveness: Mathematical Modeling of Oxygen, pH, and Glutathione ENSG00000291971 ENSG00000086991 PMC2430908__F8 Notch-Deficient Skin Induces a Lethal Systemic B-Lymphoproliferative Disorder by Secreting TSLP, a Sentinel for Epidermal Integrity ENSG00000168214 ENSG00000145777 PMC4485330__F1 Regulation of the interleukin (IL)–17 axis is essential for oral immunity and homeostasis ENSG00000115415 ENSG00000134982 ENSG00000168610 PMC8350546__F7 NANOS2 suppresses the cell cycle by repressing mTORC1 activators in embryonic male germ cells ENSG00000146857 ENSG00000136938 ENSG00000188425 PMC12130335__F9 MAVS’ role in MIRI ENSG00000088888 ENSG00000082512 ENSG00000107201 ENSG00000171791 ENSG00000175104 PMC5568613__F1 Pathway of corticosteroid synthesis in the adrenal cortex ENSG00000179142 PMC4849781__F2 HepatoDyn: A Dynamic Model of Hepatocyte Metabolism That Integrates 13C Isotopomer Data ENSG00000099864 ENSG00000154016 PMC5124618__F1 Changes in the VE response to inflammatory stimuli during sepsis ENSG00000003436 ENSG00000005381 PMC6518927__F6 Network of genes targeted by miR-21, based on miRTarBase predictions and analysed by String ENSG00000136158 ENSG00000168040 ENSG00000153561 ENSG00000288461 ENSG00000141034 ENSG00000163412 ENSG00000110395 ENSG00000164056 ENSG00000198742 ENSG00000100985 ENSG00000064012 ENSG00000139687 ENSG00000282899 ENSG00000187678 PMC5320444__F5 Comparative physiological and transcriptomic analyses provide integrated insight into osmotic, cold, and salt stress tolerance mechanisms in banana PMC7318076__F2 Representative strategies to optimize cytoplasmic signaling of CD28ζ CAR ENSG00000100385 ENSG00000168610 PMC5678957__F1 Cell biology of APOL1 ENSG00000112561 ENSG00000168610 PMC6206573__F8 Ban-Xia-Xie-Xin-Tang on TNF signaling pathway ENSG00000110711 ENSG00000167207 ENSG00000102871 ENSG00000162924 ENSG00000168040 ENSG00000127191 ENSG00000164305 ENSG00000105364 ENSG00000078747 ENSG00000198517 ENSG00000056558 ENSG00000131323 ENSG00000128342 PMC10035756__F5 State-of-the-art therapeutic strategies for targeting cancer stem cells in prostate cancer ENSG00000134982 ENSG00000173039 ENSG00000168036 ENSG00000128602 PMC3233626__F5 NIRF interaction network ENSG00000153487 ENSG00000115750 ENSG00000135446 ENSG00000132646 ENSG00000147133 ENSG00000123374 ENSG00000105810 PMC8596927__F12 TRPV4-induced Müller cell gliosis and TNFA elevation-mediated retinal ganglion cell apoptosis in glaucomatous rats via JAK2/STAT3/NFKB pathway ENSG00000131095 ENSG00000168610 PMC5587602__F7 Sodium butyrate has context-dependent actions on dipeptidyl peptidase-4 and other metabolic parameters ENSG00000197635 ENSG00000125538 PMC3313666__F7 Outline of the mevalonate pathway ENSG00000070831 ENSG00000163914 PMC4822123__F8 Rac1 modulates the formation of primordial follicles by facilitating STAT3-directed Jagged1, GDF9 and BMP15 transcription in mice ENSG00000164404 ENSG00000130385 ENSG00000106410 ENSG00000198793 ENSG00000168610 PMC9528772__F8 Sirt6 deficiency contributes to mitochondrial fission and oxidative damage in podocytes via ROCK1‐Drp1 signalling pathway ENSG00000067900 ENSG00000077463 ENSG00000087274 PMC3726964__F3 Regulation of the EMT Pathway and Tec kinase signaling in Calu-6 compared to U1752 ENSG00000176692 ENSG00000169554 ENSG00000198742 ENSG00000136869 ENSG00000026103 PMC4037911__F1 Bid can be activated by multiple proteases in response to a variety of pathophysiological signals ENSG00000285121 ENSG00000168040 PMC8997759__F1 Liquid–Liquid Phase Separation in Cancer Signaling, Metabolism and Anticancer Therapy ENSG00000183735 ENSG00000186575 ENSG00000164430 PMC5244366__F1 Predicting Drug Combination Index and Simulating the Network-Regulation Dynamics by Mathematical Modeling of Drug-Targeted EGFR-ERK Signaling Pathway ENSG00000157764 ENSG00000138798 ENSG00000146648 PMC305600__F7 An EGF receptor/Ral-GTPase signaling cascade regulates c–Src activity and substrate specificity ENSG00000169291 ENSG00000291971 ENSG00000168610 ENSG00000146648 PMC6975143__F1 Unfolded protein response (UPR).Under normal conditions PERK, IRE1, and ATF6A are sequestered in an inactive state in the ER via their associations with BiP ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8989153__F1 Heterogeneous Causes of Cushing Syndrome Resulting From Primary Macronodular Adrenal Hyperplasia (PMAH) ENSG00000138039 ENSG00000140691 ENSG00000185231 ENSG00000004487 ENSG00000148680 ENSG00000126895 ENSG00000010310 PMC9461655__F9 Novel methylated cation channel TRPM4 inhibited colorectal cancer metastasis through Ca2+/Calpain-mediated proteolysis of FAK and suppression of PI3K/Akt/mTOR signaling pathway ENSG00000087245 ENSG00000167323 ENSG00000293604 ENSG00000198793 ENSG00000100985 PMC4031445__F2 Signal transduction by prostaglandin receptor EP2 ENSG00000291971 ENSG00000168036 ENSG00000146648 ENSG00000108518 PMC11907984__F2 Main function of CBXs family proteins ENSG00000151376 ENSG00000101945 ENSG00000173894 ENSG00000183741 ENSG00000277258 PMC3047603__F3 CYP17 inhibitors for prostate cancer therapy ENSG00000135437 ENSG00000162600 ENSG00000203859 PMC11907984__F3 Details of CBX members regulate Wnt/Beta-catenin, Hippo, MARK signalling pathways in tumours and mechanism ENSG00000066468 ENSG00000173894 ENSG00000109805 ENSG00000145321 ENSG00000198074 ENSG00000168036 ENSG00000122565 ENSG00000141570 ENSG00000142279 PMC11907984__F4 Details of CBX members regulate PI3K/AKT/mTOR, NFKB signalling pathways in tumours and mechanism ENSG00000173894 ENSG00000150991 ENSG00000163220 ENSG00000198793 ENSG00000169047 ENSG00000173599 ENSG00000141570 ENSG00000121879 ENSG00000171608 ENSG00000146648 ENSG00000173456 PMC9224557__F5A Key Immune-Related Genes in the Heart Following Burn Injury ENSG00000101751 ENSG00000170458 ENSG00000196549 ENSG00000015285 ENSG00000135517 PMC11907984__F5 Details of CBX members regulate TGFB, Notch, HFI-1, P53/P21, E2F1/BIRC5, Rho GTPase, PRDM1/c-FOS signalling pathways in tumours and mechanism ENSG00000182481 ENSG00000087245 ENSG00000138639 ENSG00000259207 ENSG00000105329 ENSG00000112715 ENSG00000165238 ENSG00000065978 ENSG00000167772 ENSG00000150991 ENSG00000163914 ENSG00000173599 ENSG00000122565 ENSG00000141570 ENSG00000146648 ENSG00000196363 PMC8739678__F3 FcG receptors in HER2-targeted breast cancer therapy ENSG00000084774 ENSG00000115317 PMC5667541__F2 Protein O-GlcNAcylation: emerging mechanisms and functions ENSG00000047410 ENSG00000100522 ENSG00000147162 ENSG00000198408 ENSG00000169375 ENSG00000013375 PMC4882719__F2 Epigallocatechin Gallate Nanodelivery Systems for Cancer Therapy ENSG00000146648 PMC11354872__F2 Short chain fatty acids (SCFAs) and antioxidant roles against CRC development ENSG00000162711 ENSG00000166278 ENSG00000079999 PMC7012898__F1 Upstream and downstream targets of the TOR Complex (TORC) in plants PMC5667541__F4 Protein O-GlcNAcylation: emerging mechanisms and functions ENSG00000177169 ENSG00000184156 ENSG00000147162 ENSG00000198408 PMC9488999__F1 Is mitochondrial dysfunction a driving mechanism linking COPD to nonsmall cell lung carcinoma? ENSG00000162711 ENSG00000088888 ENSG00000125538 ENSG00000158828 PMC6256059__F1 Notch receptor maturation, ligand dependent and independent activation pathway and targetable steps ENSG00000140564 ENSG00000137845 PMC4558162__F1 OVOL guides the epithelial-hybrid-mesenchymal transition ENSG00000168610 PMC3772387__F8 Recruitment of FLNa, IQGAP1 and RacGAP1 to active B1 integrin regulates Rac1 activity ENSG00000140575 PMC4677908__F6 Genomic and transcriptomic features of central carbon metabolism in C ENSG00000197713 ENSG00000173599 ENSG00000070669 PMC3461903__F2 New molecular insights into peripheral T cell lymphomas ENSG00000105397 ENSG00000115415 ENSG00000134853 ENSG00000168610 ENSG00000197461 PMC8228270__F1 HERC5 and the ISGylation Pathway: Critical Modulators of the Antiviral Immune Response ENSG00000213928 ENSG00000187608 ENSG00000105397 ENSG00000156587 PMC8228270__F2 HERC5 and the ISGylation Pathway: Critical Modulators of the Antiviral Immune Response ENSG00000187608 ENSG00000156587 PMC4821889__F8 Zyxin-Siah2–Lats2 axis mediates cooperation between Hippo and TGFB signalling pathways ENSG00000181788 ENSG00000150457 ENSG00000131023 PMC5514964__F6 Regulatory functional territory of PLK-1 and their substrates beyond mitosis ENSG00000012048 ENSG00000197579 ENSG00000051180 ENSG00000075218 ENSG00000166851 ENSG00000276876 ENSG00000139618 PMC6769927__F4 The different Transforming Growth Factor B (TGFB) family members on articular cartilage biology and osteoarthritis (OA) development ENSG00000170365 ENSG00000154736 ENSG00000125398 ENSG00000149968 ENSG00000162551 ENSG00000116690 ENSG00000168610 PMC6769927__F2 Transforming growth factor B (TGFB) family SMAD-dependent signaling ENSG00000121989 ENSG00000170365 ENSG00000125398 ENSG00000105329 ENSG00000120693 ENSG00000156574 ENSG00000204217 ENSG00000114739 PMC6769927__F3 Transforming growth factor B (TGFB) family SMAD-independent signaling ENSG00000162889 ENSG00000172216 ENSG00000132478 ENSG00000185591 ENSG00000160691 PMC3907751__F1 ROS generation and its effect on angiogenesis ENSG00000005381 PMC7247360__F1 Impact of Transcription Factor Prospero Homeobox 1 on the Regulation of Thyroid Cancer Malignancy ENSG00000124102 ENSG00000157764 ENSG00000121879 PMC3415277__F6 Identification of multiple disrupted components in a biological pathway ENSG00000132906 ENSG00000002330 ENSG00000042832 ENSG00000138798 ENSG00000120875 ENSG00000169032 ENSG00000100485 ENSG00000160691 ENSG00000068028 ENSG00000163235 ENSG00000136997 ENSG00000124181 ENSG00000146648 ENSG00000126458 PMC2904169__F1 Hypoxia-inducible factor (HIF)-2 regulates erythropoietin (EPO) ENSG00000179348 PMC4234705__F2 Eph Receptor Tyrosine Kinases in Cancer Stem Cells ENSG00000142627 ENSG00000198793 PMC8533163__F8 Bacillus amyloliquefaciens SC06 Induced AKT–FOXO Signaling Pathway-Mediated Autophagy to Alleviate Oxidative Stress in IPEC-J2 Cells ENSG00000126775 ENSG00000171791 ENSG00000096717 ENSG00000145782 ENSG00000057663 PMC4561380__F6 Unveiling the metabolic potential of two soil-derived microbial consortia selected on wheat straw PMC4991449__F8 Adipocytes WNT5a mediated dedifferentiation: a possible target in pancreatic cancer microenvironment ENSG00000169071 ENSG00000120057 ENSG00000168610 PMC3207123__F1 A view of CD133 expression as it relates to variety of normal tissue and cancer stem cells ENSG00000198793 ENSG00000121966 PMC8486596__F2 Cellular senescence in cancer: from mechanisms to detection ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000198793 ENSG00000136997 ENSG00000123374 ENSG00000105810 PMC8479832__F1 Purinergic signaling in the modulation of redox biology ENSG00000005381 PMC9684343__F7 CRISPR Cas9-mediated ablation of pyruvate carboxylase gene in colon cancer cell line HT-29 inhibits growth and migration, induces apoptosis and increases sensitivity to 5-fluorouracil and glutaminase inhibitor ENSG00000173599 ENSG00000169710 PMC8479832__F2 Purinergic signaling in the modulation of redox biology ENSG00000162711 ENSG00000125538 ENSG00000164305 PMC12019274__F1 Effect of aberrantly expressed long non-coding RNAs on cell death in different modes ENSG00000278718 ENSG00000162711 ENSG00000151012 ENSG00000167468 ENSG00000168404 ENSG00000096717 ENSG00000285379 ENSG00000123908 PMC4324544__F8 Competitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model ENSG00000002330 ENSG00000168040 ENSG00000026103 PMC8992594__F4 Emerging actionable targets to treat therapy-resistant colorectal cancers ENSG00000089692 ENSG00000163599 ENSG00000173039 ENSG00000112715 PMC9688455__F1 PARP Inhibitors in Cancer Immunotherapy: Potential Friends to Immune Activating Molecules and Foes to Immune Checkpoints ENSG00000149311 ENSG00000175054 ENSG00000149554 PMC8992594__F2 Emerging actionable targets to treat therapy-resistant colorectal cancers ENSG00000132906 ENSG00000019991 ENSG00000142627 ENSG00000002330 ENSG00000157764 ENSG00000065361 ENSG00000163235 ENSG00000138798 ENSG00000146648 PMC8992594__F3 Emerging actionable targets to treat therapy-resistant colorectal cancers ENSG00000157764 ENSG00000139567 ENSG00000091879 ENSG00000112715 PMC3880999__F1 Molecular details of BAFF/BAFFR-mediated activation of NFKB2 signaling pathway ENSG00000104856 ENSG00000131323 ENSG00000127191 ENSG00000109670 PMC7892976__F2 Se transport across blood–brain barrier (BBB) and blood–cerebrospinal fluid barrier (BCB) ENSG00000183291 ENSG00000167468 ENSG00000157193 ENSG00000250722 ENSG00000178980 PMC7568161__F1 Proposed pathway underlying rh-CSF1 provided neuroprotection ENSG00000184371 ENSG00000197943 ENSG00000175567 PMC153613__F4 Highlights of key changes in cell cycle, differentiation, and metabolism-related transcripts ENSG00000177189 ENSG00000108861 ENSG00000050748 ENSG00000135446 ENSG00000118971 PMC7469991__F1 Common signaling pathway with miRNAs involved in the different malignant phenotypes of gastric cancer ENSG00000168283 ENSG00000028277 ENSG00000168036 ENSG00000176105 ENSG00000157765 ENSG00000168610 PMC6035417__F1 Molecular mechanism of apoptosis and necroptosis ENSG00000137275 ENSG00000102871 ENSG00000168404 ENSG00000285379 PMC3545927__F6 High-Resolution Analysis and Functional Mapping of Cleavage Sites and Substrate Proteins of Furin in the Human Proteome ENSG00000170365 ENSG00000107404 ENSG00000140564 ENSG00000285109 ENSG00000134982 PMC9563506__F9 PCSK9 promotes the progression and metastasis of colon cancer cells through regulation of EMT and PI3K/AKT signaling in tumor cells and phenotypic polarization of macrophages ENSG00000177575 ENSG00000170558 ENSG00000125538 ENSG00000138755 ENSG00000118520 ENSG00000100985 ENSG00000169174 PMC6953059__F1 Steps involved in the biogenesis and functions of miRNAs ENSG00000128191 ENSG00000132341 PMC6799833__F7 Potential mechanisms of fluoxetine in the remission of AD ENSG00000142192 ENSG00000169375 PMC9664042__F1 Gasdermin D as a cellular switch to orientate immune responses via IL-33 or IL-1B ENSG00000278718 ENSG00000137033 ENSG00000125538 PMC7614756__F6 Effect of NRP1 on the TGFBR2-VE-cadherin pathway in regulating adherens junctions and inflammatory responses ENSG00000169248 ENSG00000107562 ENSG00000081041 ENSG00000105329 ENSG00000163739 ENSG00000108342 ENSG00000168811 ENSG00000132693 ENSG00000108691 ENSG00000161921 ENSG00000188404 ENSG00000184371 ENSG00000096717 PMC6337329__F6 Proposed model of molecular interactions and clustering analysis ENSG00000070831 ENSG00000198793 ENSG00000067900 ENSG00000148484 ENSG00000197702 PMC4631757__F10 The interaction between corneal stroma (canonical Wnt signaling) and epithelium (Bmp4 signaling) during mouse corneal development ENSG00000170365 ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000167074 PMC5496044__F1 Schematic diagram of domain structure for LRP1 and LDLR ENSG00000140564 ENSG00000130164 ENSG00000138798 PMC6799833__F4 Autophagy pathway ENSG00000177169 ENSG00000110497 ENSG00000198382 ENSG00000126775 ENSG00000144848 ENSG00000145782 ENSG00000057663 ENSG00000062716 PMC9523483__F2 OncomiRs as noncoding RNAs having functions in cancer: Their role in immune suppression and clinical implications ENSG00000168036 ENSG00000231179 ENSG00000204520 PMC5514916__F8 NFkB is essential for activin-induced colorectal cancer migration via upregulation of PI3K-MDM2 pathway PMC4071053__F2 Molecular network generated by Ingenuity Pathway Analysis (IPA) of highly significant gene changes in human RPE cells after in vitro stimulation with AGE (10 μg/mL) ENSG00000169248 ENSG00000183486 ENSG00000115267 ENSG00000185745 ENSG00000184979 ENSG00000135899 ENSG00000132530 ENSG00000138035 ENSG00000111537 ENSG00000134321 ENSG00000116194 ENSG00000163840 ENSG00000115415 PMC4071053__F3 Interferon Signaling Pathway identified by Ingenuity software ENSG00000068079 ENSG00000213928 ENSG00000111537 ENSG00000115415 ENSG00000033800 ENSG00000125347 ENSG00000230034 PMC10483736__F1 Combining old and new concepts in targeting telomerase for cancer therapy: transient, immediate, complete and combinatory attack (TICCA) ENSG00000166340 ENSG00000178971 ENSG00000257949 ENSG00000164362 ENSG00000107960 ENSG00000128513 PMC12017889__F1 Reported regulatory mechanisms of ferroptosis ENSG00000151012 ENSG00000167468 ENSG00000198793 ENSG00000167996 ENSG00000111684 ENSG00000115107 ENSG00000167419 PMC6390333__F1 De novo biosynthesis of various aromatic compounds derived from the SHK and aromatic amino acid biosynthesis pathway ENSG00000171759 ENSG00000150787 ENSG00000128602 ENSG00000062485 PMC12017889__F3 Relationship between ferroptosis and immunity ENSG00000111537 ENSG00000151012 ENSG00000115415 ENSG00000189403 PMC8555666__F10 Differential Association of Free, Conjugated, and Bound Forms of Polyamines and Transcript Abundance of Their Biosynthetic and Catabolic Genes During Drought/Salinity Stress in Tomato (Solanum lycopersicum L.) Leaves ENSG00000081181 ENSG00000167941 PMC5342554__F8 NTS/NTR1 co-expression enhances epithelial-to-mesenchymal transition and promotes tumor metastasis by activating the Wnt/Beta-catenin signaling pathway in hepatocellular carcinoma ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC6271612__F1 The molecular mechanism behind mitophagy after stroke ENSG00000116688 ENSG00000171109 PMC3976614__F1 Modulation of mitochondrial dysfunction by the PINK1/PARKIN pathway ENSG00000116688 ENSG00000158828 PMC8545469__F7 T6SS translocates a micropeptide to suppress STING-mediated innate immunity by sequestering manganese ENSG00000183735 ENSG00000164430 PMC6571408__F9 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of MAGE A11 in patients with esophageal squamous cell carcinoma (ESCC) ENSG00000198793 PMC3676391__F1 Saccharomyces cerevisiae Assay System to Investigate Ligand/AdipoR1 Interactions That Lead to Cellular Signaling ENSG00000157500 ENSG00000099985 ENSG00000159346 PMC6796858__F10 Cortical branched actin controls the G1/S transition ENSG00000172725 ENSG00000242498 PMC7464279__F7 Synergistic effect of cyclopamine and rapamycin ENSG00000106571 ENSG00000128602 PMC8234594__F1 Epithelial–Mesenchymal Transition Associated with Head and Neck Squamous Cell Carcinomas: A Review ENSG00000056558 ENSG00000168036 ENSG00000129514 ENSG00000131323 ENSG00000127191 PMC8728363__F6 Tumor-associated macrophages: potential therapeutic strategies and future prospects in cancer ENSG00000272398 ENSG00000121807 PMC7226088__F2 Regulatory signaling pathways in MDSC development and functions ENSG00000143546 ENSG00000115415 ENSG00000172936 ENSG00000118520 ENSG00000168610 ENSG00000285379 PMC9374671__F1 Nicotinamide mononucleotide ameliorates adriamycin-induced renal damage by epigenetically suppressing the NMN/NAD consumers mediated by Twist2 ENSG00000143799 ENSG00000123572 ENSG00000130649 ENSG00000096717 PMC3359728__F3 Regulation of homeostatic AMPAR trafficking and turnover ENSG00000170558 ENSG00000198576 ENSG00000168036 PMC1383482__F1 Tumor Necrosis Factor by Microbial Pathogens ENSG00000102871 ENSG00000168040 PMC8249562__F4 Mitochondrial Hsp90 TRAP1 and Alzheimer’s Disease ENSG00000215021 ENSG00000284774 ENSG00000170558 ENSG00000197540 ENSG00000158828 ENSG00000168610 PMC8816937__F7 Schematic diagram showing that the ETV4 functions in HCC metastasis ENSG00000004975 ENSG00000137673 ENSG00000175832 ENSG00000136997 ENSG00000168036 PMC6477167__F1 Interplay between HPV-infected keratinocytes and the local immune microenvironment critically influences cervical carcinogenesis.HPV suppresses inflammatory signaling in the host keratinocyte ENSG00000150782 ENSG00000108691 ENSG00000125538 ENSG00000126353 ENSG00000115009 PMC7734179__F1 Cytosolic DNA sensing pathways ENSG00000278718 ENSG00000239732 ENSG00000163568 ENSG00000198793 ENSG00000172936 ENSG00000175104 PMC4662454__F4 Targeting cancer by binding iron: Dissecting cellular signaling pathways ENSG00000291971 ENSG00000168610 PMC4662454__F5 Targeting cancer by binding iron: Dissecting cellular signaling pathways ENSG00000281324 ENSG00000134982 ENSG00000170558 ENSG00000168036 PMC3378977__F1 Summary of the suggested mechanism for the regulation of MMPs and TIMPs in the paracrine interplay between SCC-25 cells and fibroblasts ENSG00000100234 ENSG00000026508 PMC4220839__F2 Cytosolic DNA recognition pathway for IL-1B production ENSG00000187796 ENSG00000163568 ENSG00000125538 PMC9170611__F4 Decrypting a path based approach for identifying the interplay between PI3K and GSK3 signaling cascade from the perspective of cancer ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000164327 PMC9292562__F3 Nicotinamide adenine dinucleotide metabolism in the immune response, autoimmunity and inflammageing ENSG00000105835 ENSG00000125538 ENSG00000049768 PMC7460532__F1 Phosphatase and tensin homolog (PTEN) signaling pathway and its interactions ENSG00000198793 ENSG00000166278 PMC9292562__F4 Nicotinamide adenine dinucleotide metabolism in the immune response, autoimmunity and inflammageing ENSG00000105835 ENSG00000129167 ENSG00000096717 ENSG00000106546 PMC9292562__F2 Nicotinamide adenine dinucleotide metabolism in the immune response, autoimmunity and inflammageing ENSG00000105835 ENSG00000205221 ENSG00000123572 ENSG00000278488 PMC10779434__F2 The actin cytoskeleton within the foot processes ENSG00000070831 ENSG00000140575 ENSG00000198087 ENSG00000130402 ENSG00000137672 ENSG00000084112 PMC7554583__F1 Mitochondrial stress responses in cystic fibrosis ENSG00000006712 ENSG00000169136 ENSG00000158828 ENSG00000171791 ENSG00000125656 PMC7554583__F2 mtDAMPs in cystic fibrosis Under stress, mitochondria generate and/or release immunogenic molecules, named mitochondrial damage associated molecular patters (mtDAMPs), that influence significantly the inflammatory response in CF lung disease ENSG00000162711 ENSG00000156026 ENSG00000169136 ENSG00000091106 PMC3743096__F4 Signal integration by mTORC1 coordinates nutrient input with biosynthetic output ENSG00000134086 ENSG00000128272 ENSG00000144895 ENSG00000175792 PMC2938197__F1 Predicted hydroxy/hydroperoxy wybutosine biosynthesis pathway and domain architecture of key enzymes involved in its synthesis ENSG00000198874 PMC5707548__F1 ATM (ataxia telangiectasia mutated)-mediated DDR (DNA damage response) signaling pathway ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000163961 ENSG00000112130 PMC5535871__F5 Functional overview of ANRIL and pathways ENSG00000149311 ENSG00000198901 PMC4698399__F8 Processes responsible for the synthesis, trafficking, and degradation of membrane proteins ENSG00000003056 ENSG00000147044 ENSG00000137145 ENSG00000102189 ENSG00000013016 ENSG00000005893 ENSG00000084733 ENSG00000276600 ENSG00000146648 ENSG00000024422 ENSG00000124839 PMC8286837__F1 Hypoxia activated UPR and DDR pathways ENSG00000149311 ENSG00000175054 ENSG00000128272 ENSG00000144895 ENSG00000198793 ENSG00000100219 PMC4384293__F2 Paradoxical roles of autophagy induced by the tumor microenvironment during different stages of tumor development ENSG00000128272 ENSG00000144895 PMC4548922__F2 Decreased fatty acid oxidation contributes to CKD progression ENSG00000135218 ENSG00000105329 PMC11763227__F7 FGF19 working model ENSG00000160867 ENSG00000167910 ENSG00000180432 PMC4986275__F4 Representation of the top Canonical Pathways, Functional Annotations and Upstream Regulators detected upon analysis of target genes and their co-regulated genes ENSG00000172380 ENSG00000105329 ENSG00000172243 ENSG00000081237 ENSG00000110324 ENSG00000043462 ENSG00000168610 ENSG00000111537 ENSG00000141753 ENSG00000164136 ENSG00000283060 ENSG00000146648 ENSG00000026103 ENSG00000164342 PMC8197124__F2 Crossroads between Host Copper Metabolism and Influenza Infection ENSG00000173992 ENSG00000138495 ENSG00000123191 ENSG00000177556 PMC5983675__F2 Tumor necrosis factor receptor signaling in multiple sclerosis ENSG00000107562 ENSG00000111537 ENSG00000134853 ENSG00000128342 PMC5963198__F4 Model of miR155 activation in BMDMs exposed to C ENSG00000291971 PMC11621778__F9 Multi-omics co-analysis ENSG00000135218 ENSG00000187608 ENSG00000105329 ENSG00000196739 ENSG00000170365 ENSG00000084676 ENSG00000170893 ENSG00000108821 ENSG00000150051 ENSG00000124256 ENSG00000005339 ENSG00000146469 ENSG00000284161 ENSG00000089041 ENSG00000124493 ENSG00000237693 ENSG00000134871 ENSG00000135577 ENSG00000170425 ENSG00000162654 ENSG00000168610 ENSG00000274286 ENSG00000276561 ENSG00000288455 ENSG00000047056 ENSG00000184979 ENSG00000130304 ENSG00000074211 ENSG00000063176 ENSG00000139574 ENSG00000122188 ENSG00000100596 ENSG00000101255 ENSG00000165478 ENSG00000123892 ENSG00000019549 ENSG00000124253 ENSG00000084774 PMC2806892__F1 Methionine metabolism in vivo PMC11763227__F4 FGF19 alleviates LPS-induced hepatocytes apoptosis associated with AMPK activation in vivo and in vitro PMC5516800__F3 Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy? ENSG00000284320 ENSG00000100714 ENSG00000092621 ENSG00000135069 PMC5516800__F1 Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy? ENSG00000180210 ENSG00000114268 ENSG00000136872 ENSG00000159399 ENSG00000026103 PMC3055447__F4 A schematic diagram of pyramidal cells (triangular) and GABAergic interneurons (square) within the trisynaptic pathway of the hippocampus ENSG00000100941 ENSG00000115271 PMC5516800__F2 Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy? ENSG00000159399 ENSG00000026103 PMC5516800__F5 Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy? ENSG00000180210 ENSG00000157764 ENSG00000291971 ENSG00000136997 ENSG00000114268 ENSG00000136872 ENSG00000159399 ENSG00000026103 PMC5516800__F6 Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy? ENSG00000180210 ENSG00000114268 ENSG00000136872 ENSG00000159399 ENSG00000026103 PMC4513218__F1 Part of the tamoxifen metabolic pathway ENSG00000165841 ENSG00000197408 PMC8468752__F2 Pharmacogenomics Variability of Lipid-Lowering Therapies in Familial Hypercholesterolemia ENSG00000138075 ENSG00000138115 ENSG00000073734 ENSG00000118777 ENSG00000143921 PMC4279797__F1 Pharmacology network-based drug repurposing for CMT1A disease ENSG00000069482 ENSG00000291971 ENSG00000122877 ENSG00000101327 ENSG00000171791 ENSG00000181195 ENSG00000196689 PMC8032975__F2 Lipoproteins and their three different metabolic pathways ENSG00000138823 ENSG00000100979 PMC8468752__F1 Pharmacogenomics Variability of Lipid-Lowering Therapies in Familial Hypercholesterolemia ENSG00000138075 ENSG00000113161 ENSG00000132855 ENSG00000118777 ENSG00000169174 PMC7180987__F1 Effects of growth hormone on adipose tissue: old observations, new mechanisms ENSG00000166819 ENSG00000042832 ENSG00000112964 ENSG00000123689 PMC7989705__F2 Solute carriers (SLCs) associated with PDAC cell proliferation, angiogenesis, invasion, and metastasis ENSG00000168003 ENSG00000151012 ENSG00000198793 ENSG00000164938 ENSG00000026508 ENSG00000150457 ENSG00000168610 PMC7920467__F1 Ceramide de novo synthesis pathway ENSG00000139624 ENSG00000223802 ENSG00000154227 PMC3944264__F6 Proposed model for miR-542-3p-mediated suppression of osteoblast proliferation and differentiation ENSG00000170365 PMC7923474__F4 Label-free proteomics uncovers SMC1A expression is Down-regulated in AUB-E ENSG00000113558 ENSG00000150093 ENSG00000112118 ENSG00000176619 PMC7884645__F2 NLR in eXile: Emerging roles of NLRX1 in immunity and human disease ENSG00000164430 ENSG00000088888 ENSG00000160703 ENSG00000131323 ENSG00000175104 ENSG00000145782 ENSG00000276561 ENSG00000057663 PMC7989705__F3 Solute carrier (SLC) expression is associated with cell death ENSG00000168003 ENSG00000136868 ENSG00000151012 ENSG00000006712 ENSG00000167468 PMC2612524__F7 A potential model for contributions of F-BAR-containing adaptor proteins and PTKs in regulating FcɛRI signaling during internalization ENSG00000182511 PMC4872729__F2 Understanding the role of the kynurenine pathway in human breast cancer immunobiology ENSG00000262635 ENSG00000125968 PMC6274245__F5 Upstream signal transduction pathway leading to activation of canonical p50/p65 NFKB upon stimulation by tumor necrosis factor (TNF)A (see text for details, scheme realized with ScienceSlides) ENSG00000102871 ENSG00000127191 PMC6274245__F6 Regulation of posttranscriptional modifications of NFKB and histone H3 with and without TNFA stimulation ENSG00000103037 ENSG00000196591 ENSG00000096717 PMC3226194__F7 An integrated pathway model involving FOXA1 in breast cancer ENSG00000149311 ENSG00000012048 ENSG00000108242 ENSG00000120915 ENSG00000129514 ENSG00000051180 ENSG00000139618 PMC5976735__F3 Main signaling pathways involved for 12 miRNAs differentially expressed after exercise from EVs purified from rat’s serum ENSG00000213658 ENSG00000111837 ENSG00000127948 PMC6738443__F4 Modular network regulation map of gene-related ncRNA/TFs ENSG00000084093 ENSG00000142192 ENSG00000151726 ENSG00000116691 ENSG00000125735 ENSG00000261857 ENSG00000173039 ENSG00000105656 ENSG00000253352 ENSG00000128272 ENSG00000130164 ENSG00000196549 ENSG00000015285 ENSG00000135517 PMC10889827__F3 Ihh signaling plays a critical role in periosteal bone biology and shows complex interaction with other molecules ENSG00000170365 ENSG00000128602 ENSG00000163501 PMC10889827__F4 Wnt signaling has important indirect as well as direct effects on PDCs ENSG00000170365 ENSG00000134982 ENSG00000188064 ENSG00000168036 ENSG00000163501 PMC10889827__F1 BMP signaling represents a fundamental signaling profile in periosteal effects ENSG00000152266 ENSG00000154342 PMC10889827__F2 PDGF signaling mediates periosteal activation and blocks BMP2-induced osteogenesis ENSG00000170365 PMC8005457__F7 Pentamethoxylated flavone from Glycosmis ovoidea promotes apoptosis through the intrinsic pathway and inhibits migration of MCF-7 breast cancer cells ENSG00000143799 ENSG00000171791 PMC6203329__F2 Cellular oxidative and genotoxic stress responses converge on the AMPK/mTORC1 pathway ENSG00000149311 PMC7408280__F3 Transcriptional modulation of the inflammatory response in PD ENSG00000178573 ENSG00000125538 PMC9636152__F1 DNA damage signaling pathway ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000163961 ENSG00000080345 ENSG00000112130 PMC4253418__F7 Targeting tyrosine-kinases and estrogen receptor abrogates resistance to endocrine therapy in breast cancer ENSG00000134057 ENSG00000291971 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000277641 PMC5059721__F6 Carbon Ion-Irradiated Hepatoma Cells Exhibit Coupling Interplay between Apoptotic Signaling and Morphological and Mechanical Remodeling ENSG00000166278 PMC6539048__F5 Transcriptomic Pattern of Genes Regulating Protein Response and Status of Mitochondrial Activity Are Related to Oocyte Maturational Competence—A Transcriptomic Study ENSG00000171105 ENSG00000159388 ENSG00000101938 ENSG00000146247 ENSG00000095015 ENSG00000134363 ENSG00000122877 ENSG00000117298 ENSG00000165280 ENSG00000163453 ENSG00000170606 ENSG00000265972 ENSG00000112715 ENSG00000118971 ENSG00000119048 ENSG00000169836 ENSG00000167772 ENSG00000157227 ENSG00000151617 ENSG00000163501 ENSG00000125968 ENSG00000155090 PMC6539048__F6 Transcriptomic Pattern of Genes Regulating Protein Response and Status of Mitochondrial Activity Are Related to Oocyte Maturational Competence—A Transcriptomic Study ENSG00000171105 ENSG00000157227 ENSG00000159388 ENSG00000122877 ENSG00000163453 ENSG00000112715 ENSG00000163501 ENSG00000125968 ENSG00000155090 PMC9530954__F12 Identification of the molecular subgroups in Alzheimer's disease by transcriptomic data ENSG00000007944 ENSG00000050748 ENSG00000069329 ENSG00000103260 ENSG00000171206 ENSG00000135678 ENSG00000136942 ENSG00000130024 ENSG00000117410 ENSG00000166164 ENSG00000154917 ENSG00000103449 ENSG00000063177 ENSG00000166337 ENSG00000114279 ENSG00000169567 ENSG00000188783 PMC5616168__F13 Schematic diagram for the ADTRP signaling pathway ENSG00000111863 ENSG00000084774 PMC6600571__F1 Skeletal muscle insulin signalling ENSG00000169047 ENSG00000198793 PMC6478619__F1 Yes-associated protein and WW-domain-containing transcriptional co-activator with PDZ-binding motif is a point of convergence in signaling pathways ENSG00000109321 ENSG00000089685 ENSG00000163914 ENSG00000169047 ENSG00000164327 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC9013714__F7 Blockade of the P2Y2 Receptor Attenuates Alcoholic Liver Inflammation by Targeting the EGFR-ERK1/2 Signaling Pathway ENSG00000125538 ENSG00000146648 PMC8080681__F2 Aberrant HNF4Alpha-related cell signaling pathways in cancer ENSG00000168036 ENSG00000168610 ENSG00000115594 ENSG00000196628 PMC6760925__F5 Genes lost during the transition from land to water in cetaceans highlight genomic changes associated with aquatic adaptations ENSG00000147162 ENSG00000291507 ENSG00000134640 PMC554120__F8 The inhibition of Myt1 in the meiotic and mitotic cell cycles in Xenopus ENSG00000172680 ENSG00000276876 PMC7072214__F5 Phosphatidylinositol 3-kinase (PI3K) signaling pathway and signaling outputs ENSG00000002330 ENSG00000135446 ENSG00000118515 ENSG00000105810 ENSG00000171791 PMC7072214__F4 Apoptotic signaling pathways with the reported interaction of Rab proteins ENSG00000171791 ENSG00000168040 PMC3742358__F3 Pathway of nucleotide excision repair and translesion synthesis ENSG00000076924 ENSG00000132646 ENSG00000163945 ENSG00000136936 PMC5342378__F8 PAX3 is a novel tumor suppressor by regulating the activities of major signaling pathways and transcription factor FOXO3a in thyroid cancer ENSG00000135446 ENSG00000170558 ENSG00000152977 ENSG00000135903 ENSG00000116717 ENSG00000105810 PMC12012940__F1 Identification and characterization of the core HPARBP network ENSG00000181163 ENSG00000100227 ENSG00000182944 ENSG00000129351 ENSG00000149273 ENSG00000077312 ENSG00000114503 ENSG00000139726 ENSG00000244462 ENSG00000104907 ENSG00000145216 ENSG00000120158 ENSG00000143977 ENSG00000167088 ENSG00000111605 ENSG00000198231 ENSG00000113649 ENSG00000114416 ENSG00000197102 ENSG00000143569 ENSG00000117360 ENSG00000124802 ENSG00000139131 ENSG00000063244 ENSG00000121774 ENSG00000125870 ENSG00000147274 ENSG00000011304 ENSG00000175792 ENSG00000132341 ENSG00000138385 PMC2582888__F8 Two parallel pathways are required for Abl-dependent cell detachment ENSG00000142627 ENSG00000198670 ENSG00000067900 ENSG00000099942 PMC7206374__F4 Potential regulatory modeling of miR126-3p and PIK3R2 in porcine GCs (pGCs) ENSG00000171105 ENSG00000105647 PMC8144021__F1 Precision Medicine for Paediatric Severe Asthma: Current Status and Future Direction ENSG00000137033 ENSG00000145777 ENSG00000166090 PMC5613059__F1 Frequent genetic alterations of PI3K/mTOR signaling pathway in HNSCC ENSG00000162409 ENSG00000164327 ENSG00000121879 ENSG00000171608 ENSG00000132356 ENSG00000146648 ENSG00000187840 PMC12012940__F7 The underlying molecular mechanisms of the specific HPARBPs and their common binding targets regulating the Wnt signaling pathway ENSG00000011304 ENSG00000281324 ENSG00000162337 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000114503 ENSG00000063244 ENSG00000129351 PMC8719641__F3 New Insights Into the Biosynthesis of Typical Bioactive Components in the Traditional Chinese Medicinal Fungus Cordyceps militaris ENSG00000150787 PMC5874430__F10 Ingenuity Pathway Analysis (IPA) diagram of the cell cycle control pathway ENSG00000175054 ENSG00000168283 ENSG00000101945 ENSG00000123374 ENSG00000169375 PMC5649056__F3 Canonical Wnt signaling and bone remodeling ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC7072285__F6 Putative inhibitory effect of 8-HD in the IRF-3 signaling pathway ENSG00000169245 ENSG00000183735 ENSG00000185745 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 PMC8501049__F10 CaMKII activation in early diabetic hearts induces altered sarcoplasmic reticulum-mitochondria signaling ENSG00000116688 ENSG00000156026 ENSG00000198626 PMC2928711__F9 Leptin upregulates VEGF in breast cancer via canonic and non-canonical signaling pathways and NFKB/HIF-1A activation ENSG00000185591 ENSG00000168610 PMC8938628__F1 Design, synthesis and evaluation of 4,7-disubstituted 8-methoxyquinazoline derivatives as potential cytotoxic agents targeting Beta-catenin/TCF4 signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8537064__F1 Molecular Mechanisms of the SLC13A5 Gene Transcription ENSG00000131473 ENSG00000198793 ENSG00000079432 ENSG00000141485 PMC5355165__F1 Crosstalk between microRNAs and the Wnt/Beta-catenin signaling pathway in cancer ENSG00000134982 ENSG00000020633 ENSG00000168036 PMC4233297__F2 Summary of myocardial cellular effects and the injury response induced by anthracyclines ENSG00000102908 ENSG00000285109 ENSG00000198793 ENSG00000136869 ENSG00000164305 ENSG00000139618 ENSG00000026103 PMC5828413__F3 PPI network of CAD genes ENSG00000167553 ENSG00000165895 ENSG00000204842 ENSG00000167554 ENSG00000102753 ENSG00000185305 ENSG00000261857 ENSG00000102452 ENSG00000125851 ENSG00000203837 ENSG00000141564 ENSG00000282825 ENSG00000182263 ENSG00000182511 ENSG00000010704 ENSG00000135100 ENSG00000285250 ENSG00000151276 ENSG00000198740 ENSG00000074211 ENSG00000112977 ENSG00000154305 ENSG00000138336 ENSG00000138193 ENSG00000122254 ENSG00000100302 ENSG00000185736 ENSG00000019186 ENSG00000179873 ENSG00000131018 ENSG00000153066 ENSG00000239305 ENSG00000047849 ENSG00000172264 ENSG00000162599 ENSG00000136448 ENSG00000136205 ENSG00000127616 ENSG00000108433 ENSG00000186469 ENSG00000122965 PMC4490154__F1 What do we know about the cardiac benefits of exercise? ENSG00000179862 PMC5513686__F1 Principal effects of chronic alcohol abuse on anabolic and catabolic mechanisms that maintain skeletal muscle mass ENSG00000169047 ENSG00000198793 PMC8401259__F5 Immune Response and Apoptosis-Related Pathways Induced by Aeromonas schubertii Infection of Hybrid Snakehead (Channa maculata♀ × Channa argus♂) ENSG00000132906 ENSG00000149311 ENSG00000291983 ENSG00000182511 ENSG00000002330 ENSG00000102871 ENSG00000138794 ENSG00000172936 ENSG00000168040 ENSG00000127191 ENSG00000164305 PMC3069685__F2 An Activating Transcription Factor 5-Mediated Survival Pathway as a Target for Cancer Therapy ENSG00000182158 ENSG00000149269 ENSG00000169136 PMC8401694__F1 Emerging Role of Nutraceuticals in Cardiovascular Calcification: Evidence from Preclinical and Clinical Studies ENSG00000170365 ENSG00000092439 ENSG00000118503 ENSG00000183840 ENSG00000168036 PMC8401694__F2 Emerging Role of Nutraceuticals in Cardiovascular Calcification: Evidence from Preclinical and Clinical Studies ENSG00000136960 ENSG00000183840 PMC5828413__F2 Coexpression network of CAD genes and metabolic pathway genes ENSG00000228716 ENSG00000130957 ENSG00000102452 ENSG00000125851 ENSG00000203837 ENSG00000156885 ENSG00000137825 ENSG00000137563 ENSG00000185352 ENSG00000116183 ENSG00000143858 ENSG00000185056 ENSG00000128050 ENSG00000100095 ENSG00000164879 ENSG00000131730 ENSG00000077009 ENSG00000165609 ENSG00000068976 ENSG00000136267 ENSG00000168282 ENSG00000092054 ENSG00000170266 ENSG00000164100 ENSG00000203859 ENSG00000157064 ENSG00000026652 ENSG00000197713 ENSG00000108515 ENSG00000074211 ENSG00000112977 ENSG00000164742 ENSG00000138193 ENSG00000122254 ENSG00000100302 ENSG00000244038 ENSG00000167325 ENSG00000019186 ENSG00000171848 ENSG00000100479 ENSG00000164398 ENSG00000164708 ENSG00000047849 PMC6113562__F3 Regulation of inflammatory arachidonic acid (AA) derivatives after Leishmania infantum or Leishmania donovani infections PMC4571721__F5 Chemokine signaling pathway map created based on KEGG pathways ENSG00000169291 ENSG00000113263 ENSG00000105639 ENSG00000026103 PMC2810291__F6 Endonuclein functions ENSG00000168610 ENSG00000138385 PMC8560782__F1 Urinary excretion of epigenetically modified DNA as a marker of pediatric ALL status and chemotherapy response ENSG00000123415 ENSG00000139372 ENSG00000129071 PMC7685174__F1 Balance of angiotensin (Ang) II and Ang-(1–7) in the renin-angiotensin system (RAS) ENSG00000130234 ENSG00000284844 PMC2861953__F2 Altered signaling pathways and mouse models of thyroid cancer ENSG00000165409 PMC4967202__F2 MMP-9 signaling in the left ventricle following myocardial infarction ENSG00000135218 ENSG00000125538 ENSG00000185591 ENSG00000121807 ENSG00000122194 PMC8131382__F7 Hypothetical model for the regulation of cell proliferation and tumorigenesis by the Notch3ICD/PTEN axis ENSG00000074181 ENSG00000198793 PMC6743293__F2 Molecular mechanisms of KLF15 in renal fibrosis and mesangial pathology ENSG00000123374 ENSG00000163884 PMC8569436__F1 STAT3 as a mediator of oncogenic cellular metabolism: Pathogenic and therapeutic implications ENSG00000291507 ENSG00000136997 ENSG00000168610 PMC8214965__F5 姜黄素通过Wnt/Beta-catenin信号通路诱导人晶状体上皮细胞的凋亡和细胞周期阻滞 ENSG00000134057 ENSG00000134982 ENSG00000172005 ENSG00000168036 PMC12043473__F2 Conversion from normal fibroblasts (NFs) to cancer-associated fibroblasts (CAFs) involves multiple molecular mechanisms ENSG00000157933 ENSG00000197081 ENSG00000137033 ENSG00000124882 ENSG00000026508 ENSG00000198670 ENSG00000168610 PMC12043473__F3 Origin of CAFs are complex, diverse, and heterogeneous ENSG00000178860 ENSG00000107562 ENSG00000168610 PMC7176765__F1 Multiple Lysine methylation regulate cellular functions of p53 ENSG00000159224 ENSG00000126457 ENSG00000048028 ENSG00000143499 ENSG00000145391 PMC4540601__F4 Differences in M1- versus M2-macrophage fueling reactions ENSG00000135218 ENSG00000118520 ENSG00000026103 PMC2997522__F2 Novel Therapies Against Aggressive and Recurrent Epithelial Cancers by Molecular Targeting Tumor- and Metastasis-Initiating Cells and Their Progenies ENSG00000128602 ENSG00000121966 PMC5967272__F1 Aberrant signaling in systemic lupus erythematosus (SLE) T cells ENSG00000137265 ENSG00000026508 ENSG00000168610 PMC8566527__F6 The mechanism of CIRT boosts anti-tumour immune responses in melanoma-bearing mice ENSG00000118520 ENSG00000168610 PMC3945331__F4 Modules identified by functional and gene expression enrichment analysis ENSG00000175866 ENSG00000102606 ENSG00000134982 ENSG00000105647 ENSG00000092820 ENSG00000196531 ENSG00000077150 ENSG00000076928 ENSG00000167941 ENSG00000163914 ENSG00000136997 ENSG00000197386 ENSG00000185591 ENSG00000196914 ENSG00000132535 ENSG00000108106 ENSG00000109756 ENSG00000136068 ENSG00000168028 ENSG00000109061 ENSG00000125814 ENSG00000005339 ENSG00000113649 ENSG00000078369 ENSG00000106299 ENSG00000100345 ENSG00000131095 ENSG00000087460 ENSG00000108518 ENSG00000067606 ENSG00000015285 ENSG00000183020 PMC3945331__F5 Additional functional modules identified by ingenuity pathway analysis ENSG00000107404 ENSG00000171105 ENSG00000005339 ENSG00000223367 ENSG00000102606 ENSG00000125755 ENSG00000134982 ENSG00000103035 ENSG00000168724 ENSG00000064393 ENSG00000198793 ENSG00000161203 ENSG00000106299 ENSG00000074319 ENSG00000105647 ENSG00000273686 ENSG00000117020 ENSG00000078053 ENSG00000100387 ENSG00000167941 ENSG00000010810 ENSG00000197386 ENSG00000122705 ENSG00000090520 PMC9102675__F2 Endothelin and RAS/ERK signaling in immunopathogenesis-related fibrosis in patients with systemic sclerosis: an updated review with therapeutic implications ENSG00000198793 PMC5727330__F1 Downstream effectors of Ras pathway including Ral pathway and their biological roles ENSG00000070831 ENSG00000163914 PMC5727330__F2 RalA/B effectors ENSG00000017797 ENSG00000070831 ENSG00000006451 PMC2975924__F3 Eph/ephrin signaling regulates intestinal cell positioning and proliferation ENSG00000004975 ENSG00000124102 ENSG00000100592 ENSG00000090776 PMC5501892__F2 Metabolic profiling of intracellular glycometabolism ENSG00000074800 ENSG00000073578 ENSG00000169047 ENSG00000136997 ENSG00000153574 ENSG00000105953 ENSG00000172340 ENSG00000131828 ENSG00000062485 PMC5501892__F4 mRNA expression of enzymes and factors involved in glycometabolism ENSG00000073578 ENSG00000169047 ENSG00000108443 ENSG00000153574 ENSG00000105953 ENSG00000172340 ENSG00000132356 ENSG00000131828 ENSG00000111725 ENSG00000115592 ENSG00000181929 ENSG00000106617 ENSG00000074800 ENSG00000162409 ENSG00000136997 ENSG00000152556 ENSG00000062485 PMC4489427__F6 Integrated analysis of alterations in key pathways in nccRCC subtypes ENSG00000143252 ENSG00000134086 ENSG00000163114 ENSG00000117118 ENSG00000112561 ENSG00000110435 PMC5661624__F3 Redox regulation of cell–cell junctions ENSG00000173039 PMC6320606__F3 Schematic model depicting the proposed signaling pathway in LH/hCG-induced the resumption of meiosis ENSG00000105664 ENSG00000164404 ENSG00000130385 ENSG00000138798 ENSG00000159899 ENSG00000146648 ENSG00000276876 PMC6941304__F1 Models of Siglec-15–ligand interaction and downstream signaling ENSG00000026508 ENSG00000175104 PMC4366058__F4 Mirin is an antiviral polyamide (AVP) sensitizer ENSG00000149311 PMC7160537__F7 Mechanism of TP-induced lung cancer cell inhibition via ribosomal stress initiation ENSG00000125691 PMC5661624__F4 Redox regulation of cell mobility ENSG00000070831 ENSG00000291971 ENSG00000168036 PMC6190877__F1 General schematic diagram of molecular players involved in sex differentiation of gonochoristic teleost with genetic sex determination ENSG00000104899 ENSG00000186766 ENSG00000125398 ENSG00000137090 PMC6365663__F2 Overview of the heme biosynthetic pathway ENSG00000144659 ENSG00000155287 ENSG00000147454 PMC9693741__F2 Advances in neovascularization after diabetic ischemia ENSG00000134086 ENSG00000145147 ENSG00000168036 PMC7810547__F2 miR-155 modulates TLR4 signaling pathway in sepsis ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC5458543__F3 Fucose metabolism pathways and variation in types of fucosylated glycans ENSG00000196968 ENSG00000138798 ENSG00000196371 ENSG00000172728 ENSG00000101346 ENSG00000180549 ENSG00000130383 ENSG00000186866 PMC2727282__F7 Proposed coloboma mechanism in Lrp6-null eyes and a possible signaling network during early eye development ENSG00000281324 ENSG00000089225 PMC7756118__F6 The signaling pathway involving in megakaryocytic differentiation in normal and leukemic marrow ENSG00000167601 ENSG00000181163 PMC8238072__F1 Experimental Drugs for Chemotherapy- and Cancer-Related Anemia ENSG00000168610 PMC4777597__F1 The 5S RNP complex (RPL5, RPL11 and 5S rRNA) regulates MDM2-p53 in response to cellular stress PMC7674854__F1 Schematic overview of insulin signaling and glucose utilization pathways in the brain ENSG00000169047 ENSG00000198793 PMC7396595__F2 In the absence of co-stimulation, typically in a T lymphocyte that has not been exposed to antigen yet (naive T cell), GSK3B is constitutively active and phosphorylates NFAT2 ENSG00000168036 ENSG00000049768 ENSG00000073861 PMC12025042__F4 Non-genomic actions of Vitamin D ENSG00000115415 ENSG00000291971 ENSG00000105516 ENSG00000019186 ENSG00000107611 ENSG00000127022 ENSG00000168610 ENSG00000137055 ENSG00000186104 PMC6235178__F1 Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor (LATS) Biosensor ENSG00000150457 ENSG00000131023 PMC8012837__F1 Trop2 signaling ENSG00000143799 ENSG00000168036 ENSG00000133961 PMC3633488__F3 Decorin’s effects on Beta-catenin and Myc stabilization by directly down-regulating EGFR and Met ENSG00000281324 ENSG00000162337 ENSG00000138798 ENSG00000136997 ENSG00000168036 ENSG00000163507 PMC3707615__F5 Encoding and Decoding Cellular Information through Signaling Dynamics ENSG00000149311 ENSG00000175054 ENSG00000138798 ENSG00000136869 ENSG00000162772 ENSG00000146648 ENSG00000064300 PMC4322839__F1 Negative feedback loops at the core of transcriptional oscillators ENSG00000114315 PMC8466058__F1 Intracellular Trafficking of Notch Receptors in Ligand-Independent Notch Activation ENSG00000148400 ENSG00000114315 ENSG00000137845 PMC7794676__F5 Pyroptosis on the tumor microenvironment ENSG00000145649 ENSG00000064012 ENSG00000164305 ENSG00000147697 ENSG00000073605 PMC8833582__F5 Inflammation, Fibrosis and Cancer: Mechanisms, Therapeutic Options and Challenges ENSG00000175104 ENSG00000168610 PMC5405080__F11 Reactive oxygen species (ROS) maintenance by redox homeostasis ENSG00000149311 ENSG00000078237 ENSG00000026103 PMC6721595__F1 Human oligodendrocyte precursor cells (hOPCs) incorporate and metabolize nervonic acid ENSG00000112367 ENSG00000197971 ENSG00000237834 PMC3230307__F1 Autophagy regulation ENSG00000198793 ENSG00000167965 PMC5535015__F1 NPD1 inhibits apoptosis during UOS ENSG00000023445 ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC9184412__F2 Dopaminergic control of Cushing’s syndrome ENSG00000069482 ENSG00000198793 PMC3928023__F3 Wiring and firing neuronal networks: Endocannabinoids take center stage ENSG00000275723 ENSG00000164535 ENSG00000070831 ENSG00000134780 PMC5381981__F1 Metabolic scheme of targeted oxylipins ENSG00000226275 PMC10779100__F1 Regulation of osteoclast formation by MERTK and TYRO3 ENSG00000153208 ENSG00000092445 ENSG00000184500 PMC10779100__F2 TAM receptors and their downstream signaling pathways in osteoblasts ENSG00000167601 ENSG00000153208 ENSG00000092445 ENSG00000134982 ENSG00000169047 ENSG00000168036 ENSG00000160293 ENSG00000140443 ENSG00000184500 PMC3720736__F2 Activation of Wnt/Beta-Catenin Pathway in Monocytes Derived from Chronic Kidney Disease Patients ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6736563__F1 DSB repair pathways ENSG00000143799 ENSG00000051180 PMC5535015__F2 Up-regulation of BIRC3 transcription by NPD1-dependent c-REL expression ENSG00000023445 ENSG00000183735 ENSG00000102871 ENSG00000131323 ENSG00000127191 PMC9278165__F6 Comparative Transcriptome and Metabolome Analysis of Resistant and Susceptible Piper Species Upon Infection by the Oomycete Phytophthora Capsici ENSG00000100422 ENSG00000084774 PMC10758851__F1 Development and Clinical Applications of PI3K/AKT/mTOR Pathway Inhibitors as a Therapeutic Option for Leukemias ENSG00000101407 ENSG00000186716 ENSG00000155792 ENSG00000164327 ENSG00000213341 ENSG00000167965 PMC10137778__F8 Whole Transcriptome Analysis of Differentially Expressed Genes in Cultured Nile Tilapia (O. niloticus) Subjected to Chronic Stress Reveals Signaling Pathways Associated with Depressed Growth ENSG00000130528 ENSG00000118729 ENSG00000198626 PMC10137778__F9 Whole Transcriptome Analysis of Differentially Expressed Genes in Cultured Nile Tilapia (O. niloticus) Subjected to Chronic Stress Reveals Signaling Pathways Associated with Depressed Growth ENSG00000166402 PMC6633870__F7 Genes were clustered in the PPI network according to string database (genes from top 10 predicted pathways in BQG-treated group versus BLM group) ENSG00000182511 ENSG00000148400 ENSG00000111344 ENSG00000256762 ENSG00000071051 ENSG00000196498 ENSG00000177519 ENSG00000006062 ENSG00000177283 ENSG00000285069 ENSG00000130669 PMC7543578__F2 Sites of action of novel treatments for Graves hyperthyroidism ENSG00000165409 ENSG00000140443 PMC9406657__F2 PI3K/AKT/mTOR-Targeted Therapy for Breast Cancer ENSG00000150907 PMC3372214__F1 Simplified schematic presentation of HCV genotype 2a-mediated blocking of the insulin signaling pathway ENSG00000169047 PMC4100379__F5 The proposed mechanism underlying the inhibitory effect of MLN4924 in prostate cancer cells ENSG00000167513 PMC3118679__F1 The networks of factors (genes product, hormones, and metabolites) potentially involved in the regulation of milk protein synthesis in lactating bovine mammary tissue ENSG00000163435 ENSG00000171105 ENSG00000173757 ENSG00000198793 ENSG00000169047 ENSG00000284161 ENSG00000167658 ENSG00000171209 ENSG00000011376 PMC3118679__F7 Overall results depicted in the networks of AA and glucose transporters and mTOR, Jak2-Stat5, insulin, and AMPK signaling with log2 fold change at 60 relative to −15 d postpartum ENSG00000171105 ENSG00000284161 ENSG00000167658 ENSG00000105656 ENSG00000171209 ENSG00000011376 ENSG00000106688 ENSG00000116251 ENSG00000174444 ENSG00000125691 ENSG00000163435 ENSG00000102104 ENSG00000105723 PMC3118679__F8 Overall results depicted in the networks of AA and glucose transporters and mTOR, Jak2-Stat5, insulin, and AMPK signaling with log2 fold change at 240 relative to −15 d postpartum ENSG00000284161 ENSG00000167658 ENSG00000171209 ENSG00000011376 ENSG00000116251 ENSG00000102104 ENSG00000174444 PMC5584741__F1 Regulation of autophagy signaling pathway ENSG00000152348 ENSG00000110497 ENSG00000198382 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000215305 ENSG00000057663 PMC3118679__F6 Overall results depicted in the networks of AA and glucose transporters and mTOR, Jak2-Stat5, insulin, and AMPK signaling with log2 fold change at 15 relative to −15 d postpartum ENSG00000125691 ENSG00000163435 ENSG00000171105 ENSG00000198793 ENSG00000284161 ENSG00000167658 ENSG00000011376 ENSG00000116251 ENSG00000102104 ENSG00000174444 PMC3952558__F2 TLR4 Signaling Pathway ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC3337621__F2 Phosphoinositide 3-Kinase Signaling in Intestinal Inflammation ENSG00000124102 ENSG00000172005 ENSG00000172936 ENSG00000049768 PMC9487140__F1 Review of potential medical treatments for middle ear cholesteatoma ENSG00000189403 ENSG00000136869 ENSG00000083799 ENSG00000010671 ENSG00000125968 PMC3633528__F1 Cytokine signaling cascades that influence tropoelastin transcription ENSG00000105329 ENSG00000163235 ENSG00000113070 ENSG00000135446 ENSG00000138798 ENSG00000177606 ENSG00000123374 ENSG00000185591 PMC6700477__F1 SHH pathway activity leading to phenotypical changes in esophageal epithelial cells ENSG00000125398 ENSG00000164690 ENSG00000128602 PMC8844485__F3 Therapeutic Potentials of Poly (ADP‐Ribose) Polymerase 1 (PARP1) Inhibition in Multiple Sclerosis and Animal Models: Concept Revisiting ENSG00000143799 ENSG00000149311 ENSG00000186716 ENSG00000125538 ENSG00000173039 ENSG00000189403 ENSG00000178685 PMC8617206__F4 JAK/STAT signaling pathway: from bench to clinic ENSG00000170365 ENSG00000213928 ENSG00000115415 ENSG00000168610 PMC6083010__F3 Ingenuity Pathway Analysis of Molecular Activation Based on Gene Expression Profiles(A) Gene expression data were analyzed by Ingenuity Pathway Analysis ENSG00000143799 ENSG00000188379 ENSG00000164251 ENSG00000150455 ENSG00000162298 ENSG00000292250 ENSG00000283781 ENSG00000111961 ENSG00000155307 ENSG00000239732 ENSG00000088888 ENSG00000006712 ENSG00000111837 ENSG00000136869 ENSG00000164342 ENSG00000178860 ENSG00000142192 ENSG00000269335 ENSG00000173039 ENSG00000213341 ENSG00000168040 ENSG00000125347 ENSG00000276561 ENSG00000007171 ENSG00000138378 ENSG00000111537 ENSG00000115415 ENSG00000172936 ENSG00000188763 PMC3006290__F1 Proposed signaling scheme for ischemic preconditioning ENSG00000145321 PMC3251883__F4 Proposed mechanism for VEGFA165 induced tumour growth ENSG00000111537 ENSG00000137504 ENSG00000159216 ENSG00000138755 ENSG00000115904 ENSG00000112715 ENSG00000100485 ENSG00000104432 ENSG00000276561 ENSG00000168685 PMC7693908__F1 Oxygen sensing mechanisms ENSG00000134086 ENSG00000073614 ENSG00000117152 PMC4398619__F5 Diagram of EGFR signaling pathway showing impact of gefitinib and erlotinib on EGFR downstream signaling proteins ENSG00000110395 ENSG00000291971 ENSG00000168610 PMC4572003__F2 Network integrating gene–metabolite associations and metabolite–metabolite correlations ENSG00000262635 ENSG00000103222 ENSG00000100033 ENSG00000146733 ENSG00000105607 ENSG00000154122 ENSG00000144644 ENSG00000084734 ENSG00000197977 ENSG00000059573 ENSG00000172482 ENSG00000111181 ENSG00000112394 ENSG00000164344 ENSG00000128928 ENSG00000291479 ENSG00000183747 ENSG00000183549 ENSG00000108523 ENSG00000113889 ENSG00000288445 ENSG00000146281 ENSG00000140386 ENSG00000119943 ENSG00000103064 ENSG00000114757 ENSG00000197587 ENSG00000276709 ENSG00000166183 ENSG00000257335 ENSG00000281879 ENSG00000099194 ENSG00000156150 ENSG00000285281 ENSG00000187105 ENSG00000095906 ENSG00000141485 ENSG00000108839 ENSG00000138115 ENSG00000149485 ENSG00000172296 ENSG00000148832 ENSG00000273592 ENSG00000106546 ENSG00000117054 ENSG00000092621 ENSG00000125166 ENSG00000135423 ENSG00000137198 ENSG00000178814 ENSG00000019549 ENSG00000171759 ENSG00000122971 PMC9093043__F1 Metabolic and epigenetic landscape of HSCs and downstream progenitors ENSG00000003137 ENSG00000173599 ENSG00000101365 PMC7544743__F1 MAL structure, pathway and dependent immune responses during infections ENSG00000120833 ENSG00000226275 ENSG00000239732 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000184216 ENSG00000010671 PMC10374606__F8 Prx II knock-down HaCaT cells are sensitive to H2O2 stimulation ENSG00000120868 ENSG00000105227 PMC6447671__F8 PKZ-mediated signaling pathway ENSG00000213928 ENSG00000159714 PMC551522__F1 The Wnt signal transduction cascade ENSG00000100592 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC3293992__F11 Suppression of the NFKB Pathway by Diesel Exhaust Particles Impairs Human Antimycobacterial Immunity ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000073756 PMC7724953__F1 MTOR pathway ENSG00000138798 ENSG00000169047 ENSG00000146648 PMC4653686__F10 Proposed model of the pro-apoptotic pathway GAPDH/Siah1 in high glucose-induced human retinal pericyte apoptosis ENSG00000196470 PMC2998162__F2 Schematics of the Hippo pathway in flies and mice ENSG00000139330 ENSG00000142192 PMC12155351__F5 Δ-9-THC-dose-dependent pathways and associated genes found in disease-specific pathways ENSG00000148346 ENSG00000125740 ENSG00000081041 ENSG00000105327 ENSG00000067057 ENSG00000100906 ENSG00000163739 ENSG00000072274 ENSG00000023909 ENSG00000132170 ENSG00000113811 ENSG00000115977 ENSG00000198855 ENSG00000265808 ENSG00000179195 ENSG00000013441 ENSG00000177606 ENSG00000205629 ENSG00000284099 ENSG00000159399 PMC5712298__F1 Immunohaemostasis and infection ENSG00000003436 ENSG00000005381 PMC9066210__F4 Biological roles and clinical significance of estrogen and androgen receptors in head and neck cancers ENSG00000129514 PMC3100780__F3 Integration of BMP, FGF and Wnt signalling at the level of Smad1 during neural induction ENSG00000170365 ENSG00000281324 ENSG00000162337 PMC3448443__F2 Defining the Molecular Nexus of Cancer, Type 2 Diabetes and Cardiovascular Disease ENSG00000198793 PMC219066__F1 Tocopherol biosynthesis in plants ENSG00000151657 ENSG00000152904 PMC7603366__F2 Dysregulated DNA damage response genes involved in pro-proliferative and apoptosis resistance characteristics of PAH-PAECs ENSG00000149311 ENSG00000012048 ENSG00000104517 ENSG00000291953 ENSG00000171759 ENSG00000128829 ENSG00000051180 ENSG00000204217 PMC8799118__F5 Discovered differentially expressed lncRNA AC010973.2 can act as a diagnostic and prognostic biomarker for colon adenocarcinoma ENSG00000157554 ENSG00000002330 ENSG00000109321 ENSG00000163235 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000163914 ENSG00000168036 ENSG00000164305 ENSG00000122008 PMC8910341__F1 Transcriptomic and Network Analyses Reveal Immune Modulation by Endocannabinoids in Approach/Avoidance Traits ENSG00000177455 ENSG00000186716 ENSG00000145321 ENSG00000010671 PMC7893122__F1 Hedgehog signaling pathway and representative inhibitors of SMO, GLI and BRD4 ENSG00000141867 ENSG00000106571 ENSG00000128602 PMC3178431__F6 p63 signaling in cancer cells ENSG00000134982 ENSG00000168036 ENSG00000168610 PMC4107983__F1 Transcriptional programs controlling endocytosis ENSG00000112561 ENSG00000146648 PMC3695880__F1 The wiring diagram of the UPR model ENSG00000128272 ENSG00000144895 PMC3166148__F3 The citric acid cycle pathway (reprinted from KEGG ) ENSG00000100412 ENSG00000172340 PMC5923365__F1 Cellular pathways affected by genes significantly mutated in ALL ENSG00000149311 ENSG00000122025 ENSG00000157764 ENSG00000110395 ENSG00000198793 ENSG00000168036 ENSG00000146648 ENSG00000179295 PMC8781990__F4 Amino Acid Sensing and Assimilation by the Fungal Pathogen Candida albicans in the Human Host ENSG00000196839 ENSG00000062485 PMC5362592__F1 Different pathways induced by ALS proteins converge on translational repression ENSG00000144895 PMC8781990__F5 Amino Acid Sensing and Assimilation by the Fungal Pathogen Candida albicans in the Human Host ENSG00000142192 ENSG00000145723 PMC3574819__F10 O6-Methylguanine DNA lesions induce an intra-S-phase arrest from which cells exit into apoptosis governed by early and late multi-pathway signaling network activation ENSG00000188486 ENSG00000149311 ENSG00000175054 PMC12203532__F5 A) GNN explainer outputs node and edge importance for each sample ENSG00000163606 ENSG00000143196 ENSG00000151148 PMC7918973__F1 Nrf2/ARE signaling pathway ENSG00000181019 ENSG00000178573 ENSG00000023909 ENSG00000079999 PMC8526709__F3 KEGG enrichments of DEGs in protein-protein interaction network (PPI) ENSG00000118972 ENSG00000152266 ENSG00000281324 ENSG00000204103 ENSG00000130522 ENSG00000113070 ENSG00000036828 ENSG00000019186 ENSG00000107485 ENSG00000185591 ENSG00000077782 ENSG00000113448 ENSG00000124827 PMC7431487__F1 Antiviral signaling pathways induced during viral infection ENSG00000183735 ENSG00000088888 ENSG00000187608 ENSG00000172936 ENSG00000131323 ENSG00000125347 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC4403607__F12 Schisandrin B inhibits cell growth and induces cellular apoptosis and autophagy in mouse hepatocytes and macrophages: implications for its hepatotoxicity ENSG00000167258 ENSG00000135446 ENSG00000198793 PMC7145358__F3 Intra- and intercellular modulation of melatonin synthesis ENSG00000065833 ENSG00000145321 PMC8417798__F9 Obesity Attenuates Ventilator-Induced Lung Injury by Modulating the STAT3–SOCS3 Pathway ENSG00000126562 ENSG00000168610 PMC6628922__F5 Gestational Binge Alcohol-Induced Alterations in Maternal Uterine Artery Transcriptome ENSG00000180210 ENSG00000051523 ENSG00000115977 ENSG00000196549 ENSG00000168036 ENSG00000089159 ENSG00000154096 PMC5686665__F1 Lipogenesis, sphingolipid, and PA synthesis pathways ENSG00000131473 ENSG00000100422 ENSG00000169710 ENSG00000119537 ENSG00000148154 PMC6497434__F1 New mechanistic insights into modifiable risk factors that promote pancreatic cancer ENSG00000107562 ENSG00000168610 ENSG00000121966 PMC5495030__F1 Canonical TGFB signaling pathway ENSG00000157933 PMC4649510__F7 Model of tissue homeostasis maintenance after an ER stress ENSG00000128272 ENSG00000100219 PMC6405822__F1 BMP signal transduction ENSG00000170365 ENSG00000137834 PMC7279047__F1 Aryl hydrocarbon receptor (AhR) signaling pathway ENSG00000110711 ENSG00000140505 ENSG00000106546 PMC9496836__F1 Sirtuin 1 in Host Defense during Infection ENSG00000105329 ENSG00000198793 ENSG00000096717 ENSG00000057663 PMC8782557__F1 Mammalian AKT, the Emerging Roles on Mitochondrial Function in Diseases ENSG00000143799 ENSG00000149311 ENSG00000169047 ENSG00000167965 ENSG00000096717 PMC6168922__F5 Signaling via the ALX/FPR2 receptor ENSG00000142192 ENSG00000171049 ENSG00000171051 PMC7849055__F5 Diabetic cardiomyopathy and potential therapeutic strategies: preclinical and clinical evidence ENSG00000135218 ENSG00000169047 PMC3934462__F1 Apoptosis signaling and cell death relevant drugs ENSG00000102871 ENSG00000120868 ENSG00000168040 PMC11040941__F6 C6orf15 promotes liver metastasis via WNT/Beta-catenin signalling in colorectal cancer ENSG00000138795 ENSG00000168036 PMC2685877__F1 Combined Yeast-derived Beta-Glucan with Anti-tumor Monoclonal Antibody for Cancer Immunotherapy ENSG00000134982 PMC5492892__F1 Molecular networks between genes involved in NB development by the data mining IPA software ENSG00000012048 ENSG00000083093 ENSG00000137674 ENSG00000164362 ENSG00000171791 ENSG00000183765 PMC3753504__F39 Activation of different death receptor signaling pathways depending on the culture conditions of hepatocytes ENSG00000168040 ENSG00000115317 PMC2906263__F3 Suppression of IFN-induced Jak-STAT signaling in hepatitis C ENSG00000184979 ENSG00000213928 ENSG00000105397 ENSG00000185436 ENSG00000126457 ENSG00000142166 PMC6318427__F2 Current model of iron sensing in the liver to regulate hepcidin production ENSG00000010704 ENSG00000140564 ENSG00000106327 PMC12153880__F1 The cGAS/STING pathway ENSG00000183735 ENSG00000164430 PMC5070595__F2 Relevant aspects of complement activation and inflammasome activation with their possible interconnection ENSG00000162711 ENSG00000125538 PMC7574648__F7 Model summarizing the functional relationship between Rab5-Rab11 GTPases and BDNF/TrkB-mediated CREB transcriptional regulation ENSG00000198793 ENSG00000198576 PMC7377856__F7 Proposed scheme for the possible mechanism of EA pretreatment suppresses CIR-induced autophagy via the SIRT1-FOXO1 signaling pathway ENSG00000150907 ENSG00000096717 PMC6664092__F6 Overview of QTG involved in organoleptic compound production ENSG00000145604 ENSG00000143194 ENSG00000146701 PMC7873566__F3 Formation of the signaling-competent IL-1R complex and downstream IL-1 signaling ENSG00000150991 ENSG00000115590 ENSG00000134070 ENSG00000169429 ENSG00000157625 ENSG00000175104 ENSG00000073756 ENSG00000184216 ENSG00000115594 PMC5876464__F1 Signaling pathway of GRP78 ENSG00000128272 PMC2676892__F3 Chronic Lymphocytic Leukemia and B and T Cells Differ in Their Response to Cyclic Nucleotide Phosphodiesterase Inhibitors ENSG00000065989 ENSG00000059804 ENSG00000119508 ENSG00000109321 ENSG00000113161 ENSG00000095794 PMC9102406__F3 Review of Toxicity Mechanism Studies of Electronic Cigarettes on Respiratory System ENSG00000106100 ENSG00000140465 ENSG00000146648 ENSG00000106546 ENSG00000079999 PMC12094572__F3 Molecular mechanisms of exercise-enhanced brain neuroplasticity by enhancing various peripheral factors ENSG00000162711 ENSG00000157500 ENSG00000105550 ENSG00000159346 PMC9526990__F1 Long non-coding RNAs affecting cell metabolism in cancer ENSG00000159399 PMC12094572__F1 Effects of ADPN on metabolism in peripheral organs and related signaling pathways ENSG00000150907 ENSG00000164136 ENSG00000159346 PMC8264452__F1 Use of Biologic Modifiers as a Bridge to Hematopoietic Cell Transplantation in Primary Immune Regulatory Disorders ENSG00000134982 ENSG00000198589 PMC8215834__F7 Zinc transporter SLC39A13/ZIP13 facilitates the metastasis of human ovarian cancer cells via activating Src/FAK signaling pathway ENSG00000291971 ENSG00000168610 PMC3454471__F5 Redox regulation of the Nrf2–ARE pathway ENSG00000178573 ENSG00000156273 ENSG00000079999 PMC3541279__F5 Pathway Analysis Reveals Common Pro-Survival Mechanisms of Metyrapone and Carbenoxolone after Traumatic Brain Injury ENSG00000110514 ENSG00000105254 ENSG00000169783 ENSG00000164690 ENSG00000168040 ENSG00000128602 ENSG00000127191 PMC6933942__F5 Summary of proposed mechanistic pathway of S1PR1-induced mechano-hypersensitivity ENSG00000162711 ENSG00000125538 ENSG00000170989 PMC3541279__F2 Pathway Analysis Reveals Common Pro-Survival Mechanisms of Metyrapone and Carbenoxolone after Traumatic Brain Injury ENSG00000142192 ENSG00000110330 ENSG00000002330 ENSG00000069482 ENSG00000100906 ENSG00000102871 ENSG00000095321 ENSG00000188992 ENSG00000127191 PMC2775236__F1 The effect of neuronal activity on the function of the miR379-410 cluster member miR-134 ENSG00000106683 PMC5416999__F11 Signaling mechanisms for PGF2A and AL-8810 stimulation of FP receptor ENSG00000291971 ENSG00000113070 ENSG00000138798 ENSG00000146648 PMC3002356__F6 Proposed model of GS-mediated apoptosis in HNSCC cells ENSG00000002330 ENSG00000168040 PMC7461721__F5 Signaling Pathways Converge on Profilin ENSG00000087245 ENSG00000134086 ENSG00000291971 ENSG00000067900 ENSG00000100985 PMC8117212__F3 Proprotein Convertases in the Regulation of the Function of Immune Cells in the Oncoimmune Response ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC6129509__F10 Pi3k-akt signaling pathway interactions ENSG00000012048 ENSG00000135446 ENSG00000123374 PMC5511646__F2 Cardiac hypertrophy (a) and cardiac fibrosis (b) signaling pathways ENSG00000285109 ENSG00000108840 PMC9138861__F7 Targeting TKI-Activated NFKB2-MIF/CXCLs-CXCR2 Signaling Pathways in FLT3 Mutated Acute Myeloid Leukemia Reduced Blast Viability ENSG00000122025 ENSG00000019582 ENSG00000077150 ENSG00000163739 ENSG00000135446 ENSG00000026508 ENSG00000169429 PMC3821580__F2 Schematic representation of the functional/physical relationship between Dystrophin-Syntrophins-nNOS pathway and miRNAs involved in such signaling, both in a WT and a DMD context ENSG00000196591 ENSG00000108821 ENSG00000198947 PMC4642996__F7 A proposed scheme for BRCA1 and Gamma-H2AX-dependent DNA repair in neurons under normal conditions and in HD ENSG00000188486 ENSG00000149311 ENSG00000012048 PMC2840670__F1 K-ras mutation governs the effects of inhibition of epidermal growth factor receptor (EGFR) on the Ras/Raf/Mek signaling pathway ENSG00000163235 ENSG00000138798 ENSG00000146648 PMC6291505__F1 The involvement of several TMEMs in tumor growth through the TGFB signaling pathway ENSG00000109084 ENSG00000167874 ENSG00000249992 ENSG00000168036 ENSG00000096092 PMC9086835__F7 LncRNA-MALAT1 Regulates Cancer Glucose Metabolism in Prostate Cancer via MYBL2/mTOR Axis ENSG00000198793 PMC5501768__F1 Scheme depicting mechanisms of resistance observed to BRAF and MEK1/2 inhibitors in vitro and in vivo ENSG00000167601 ENSG00000157764 ENSG00000146648 PMC8602198__F2 Contribution of miRNAs in the Pathogenesis of Breast Cancer ENSG00000152348 ENSG00000198382 ENSG00000198793 ENSG00000144848 ENSG00000284099 ENSG00000189403 ENSG00000099940 ENSG00000171791 ENSG00000145782 ENSG00000281857 ENSG00000057663 ENSG00000136874 PMC8602198__F1 Contribution of miRNAs in the Pathogenesis of Breast Cancer ENSG00000132906 ENSG00000002330 ENSG00000115415 ENSG00000102871 ENSG00000291971 ENSG00000067900 ENSG00000168040 ENSG00000168610 ENSG00000164305 PMC3952073__F4 TAK1 Regulates Hepatic Cell Survival and Carcinogenesis ENSG00000136535 ENSG00000168036 PMC5796038__F3 Differences in the Plasma Proteome of Patients with Hypothyroidism before and after Thyroid Hormone Replacement: A Proteomic Analysis ENSG00000196136 ENSG00000101882 ENSG00000146070 ENSG00000276798 ENSG00000229314 ENSG00000147262 ENSG00000146374 PMC3753504__F28 Influence of hepatocyte culture conditions on signaling and phenotype ENSG00000291971 PMC8547927__F3 PARP Inhibition in Prostate Cancer With Homologous Recombination Repair Alterations ENSG00000143799 ENSG00000012048 ENSG00000139618 PMC8336336__F6 Diet-derived transmission of MicroRNAs from host plant into honey bee Midgut ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000100592 ENSG00000095739 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000148175 ENSG00000100211 ENSG00000196470 PMC5862799__F3 The metabolic pathways utilized by T cells in nutrient replete versus metabolically challenging environments ENSG00000198793 ENSG00000049768 PMC9427288__F2 Systematic Review of Clinical Validated and Potential miRNA Markers Related to the Efficacy of Fluoropyrimidine Drugs ENSG00000188641 ENSG00000172831 ENSG00000137204 ENSG00000171848 ENSG00000158825 ENSG00000255974 ENSG00000147647 ENSG00000143179 PMC8903693__F4 Resistance mechanisms to inhibitors of p53-MDM2 interactions in cancer therapy: can we overcome them? ENSG00000135446 ENSG00000123374 ENSG00000120868 ENSG00000026103 PMC2787730__F9 TNF- A–inducible genes that were specifically downregulated after DC treatment but not by C95 curcumin: the cytokine and cytokine-receptor interaction pathway ENSG00000134460 ENSG00000183625 ENSG00000164399 ENSG00000274736 ENSG00000121807 ENSG00000100385 ENSG00000150281 ENSG00000131142 ENSG00000122756 ENSG00000292373 ENSG00000277236 ENSG00000108688 ENSG00000181374 ENSG00000113520 ENSG00000164400 ENSG00000128342 ENSG00000292332 ENSG00000104432 ENSG00000112486 ENSG00000275718 ENSG00000099985 ENSG00000242689 ENSG00000119535 ENSG00000147168 ENSG00000137070 ENSG00000108342 ENSG00000277943 ENSG00000145839 ENSG00000137077 ENSG00000164136 ENSG00000126353 ENSG00000275095 ENSG00000115009 ENSG00000168685 PMC4074572__F1 Key roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiology ENSG00000162711 ENSG00000081041 ENSG00000163739 ENSG00000198793 ENSG00000172936 ENSG00000136869 PMC7806239__F7 Positive Feedback Loop Between TGFB and Androgen Receptor Supports Triple-negative Breast Cancer Anoikis Resistance PMC5666340__F4 CyaA toxin of B.pertussis inhibits the TRIF-dependent signaling pathways in human monocyte derived dendritic cells (MDDC) ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC8303609__F4 KIR Receptors as Key Regulators of NK Cells Activity in Health and Disease ENSG00000291603 ENSG00000213658 ENSG00000276051 PMC7013742__F2 Putative SUR1 molecular signaling pathways beyond cerebral edema in brain injury ENSG00000108691 ENSG00000171053 ENSG00000136869 ENSG00000185591 ENSG00000131095 ENSG00000138741 ENSG00000122194 ENSG00000007171 PMC1421301__F1 Interferon Regulatory Factor Expression in Human Breast Cancer ENSG00000115415 ENSG00000168310 PMC3420877__F8 Celecoxib and GABA Cooperatively Prevent the Progression of Pancreatic Cancer In Vitro and in Xenograft Models of Stress-Free and Stress-Exposed Mice ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC10935305__F9 Graphical illustration of the interaction between the gut microbial SCFA-induced Nrf2 redox signaling pathway and LPS/ROS facilitated systemic inflammatory cytokines ENSG00000170899 ENSG00000162711 ENSG00000181019 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC7308735__F3 GPNMB contributes to a vicious circle for chronic obstructive pulmonary disease ENSG00000136997 ENSG00000164400 ENSG00000100985 ENSG00000136235 PMC4526263__F1 Cellular alterations and molecular mechanisms involved in hepatic cystogenesis ENSG00000198793 ENSG00000001626 PMC1877091__F15 PDCD10/MST4 signaling pathway and CCM protein function ENSG00000114209 PMC2856329__F9 Brx-mediated osmotic stress-activated signaling system and its implications for the immune response ENSG00000070831 ENSG00000102908 ENSG00000125538 PMC3735826__F5 miRNA-548c: a specific signature in circulating PBMCs from dilated cardiomyopathy patients ENSG00000134086 ENSG00000089685 ENSG00000196591 ENSG00000112715 ENSG00000102104 PMC7387202__F1 IGF system and its components ENSG00000197081 ENSG00000115457 ENSG00000167779 ENSG00000146678 ENSG00000115461 ENSG00000140443 PMC7937875__F7 Canonical pathway analysis ENSG00000142798 ENSG00000163220 ENSG00000000971 ENSG00000163736 ENSG00000273686 ENSG00000166278 ENSG00000196136 ENSG00000118785 ENSG00000188404 ENSG00000175899 ENSG00000118515 ENSG00000162692 ENSG00000171560 ENSG00000087116 ENSG00000062485 ENSG00000148965 PMC5384577__F2 Possible roles of Mgs1 and WRNIP1 in DNA transaction ENSG00000149311 ENSG00000124535 ENSG00000132646 ENSG00000291953 ENSG00000070950 ENSG00000130997 ENSG00000051180 ENSG00000139618 PMC8209977__F1 Homologous recombination, cancer and the ‘RAD51 paradox’ ENSG00000149311 ENSG00000012048 ENSG00000136492 ENSG00000083093 ENSG00000185379 ENSG00000108384 ENSG00000154059 ENSG00000051180 ENSG00000196712 ENSG00000139618 ENSG00000183765 PMC7028932__F2 Oncogenic pathways activated in T-ALL, the downstream signalling network of interleukin-7 (IL-7), NOTCH1, and polycomb repressor complex 2 (PRC2), and potential therapeutic targets ENSG00000148400 ENSG00000198793 ENSG00000074266 ENSG00000178691 ENSG00000109670 PMC8990307__F2 Microglia and Neuroinflammation: Crucial Pathological Mechanisms in Traumatic Brain Injury-Induced Neurodegeneration ENSG00000278718 ENSG00000162711 ENSG00000136869 PMC4177363__F5 Transcriptional response to dietary restriction in Drosophila melanogaster ENSG00000101751 ENSG00000177971 ENSG00000145912 ENSG00000241945 ENSG00000130826 ENSG00000262788 ENSG00000136718 ENSG00000291996 ENSG00000011260 ENSG00000169251 ENSG00000041802 ENSG00000126749 ENSG00000185721 ENSG00000108651 ENSG00000105664 ENSG00000141101 ENSG00000055044 ENSG00000132341 PMC7653638__F5 FGFR1 and KLB effect on endocrine vs canonical FGF signaling ENSG00000105550 ENSG00000077782 PMC2566006__F2A A Defect in Menadione Biosynthesis Induces Global Changes in Gene Expression in Staphylococcus aureus ENSG00000143252 ENSG00000073578 ENSG00000196839 ENSG00000117118 ENSG00000158825 ENSG00000094975 ENSG00000175857 PMC6698547__F2 LMP-1 rescues Smads from Smurf1-mediated proteosomal degradation ENSG00000170365 ENSG00000198742 PMC5955428__F2 Involvement of SNPs in miR-3117 and miR-3689d2 in childhood acute lymphoblastic leukemia risk ENSG00000172680 ENSG00000138798 PMC3464734__F2 Pre-treatment expression of TLR, RIG-I and IFN-beta pathway genes compared between the two patient groups ENSG00000171855 ENSG00000124256 ENSG00000213928 ENSG00000187608 ENSG00000100906 ENSG00000089127 ENSG00000115267 ENSG00000150455 ENSG00000276561 ENSG00000172183 ENSG00000169245 ENSG00000239732 ENSG00000134321 ENSG00000088888 ENSG00000263528 ENSG00000177606 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC7486775__F1 Candidate pathways supporting phosphoglycolate salvage in C ENSG00000090316 ENSG00000163114 ENSG00000166278 ENSG00000131828 PMC3366012__F2 TNIP1-mediated signaling pathways ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000146648 ENSG00000064012 ENSG00000164305 PMC3217196__F1 MicroRNAs in Mutagenesis, Genomic Instability and DNA Repair ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000113328 ENSG00000070831 PMC6202849__F2 Schema of deriving corneal cell phenotype from iPSCs ENSG00000004846 ENSG00000125398 ENSG00000137203 ENSG00000156574 ENSG00000135903 ENSG00000100146 ENSG00000118777 PMC8508869__F1 Kahweol Induces Apoptosis in Hepatocellular Carcinoma Cells by Inhibiting the Src/mTOR/STAT3 Signaling Pathway ENSG00000291971 ENSG00000198793 ENSG00000168610 PMC5323160__F10 Cell-permeable iron inhibits vascular endothelial growth factor receptor-2 signaling and tumor angiogenesis ENSG00000107338 ENSG00000070831 ENSG00000291971 ENSG00000010810 ENSG00000112715 PMC7697192__F2 Kin regulates macrophage polarization through MAPK, NFKB, and STAT6 signaling pathways ENSG00000151657 ENSG00000125538 ENSG00000118520 PMC4384220__F1 PI3K-Akt-mTOR signaling pathway ENSG00000002330 PMC8645962__F1 Acetylation in Tumor Immune Evasion Regulation ENSG00000094631 ENSG00000187531 ENSG00000196591 ENSG00000077463 ENSG00000100429 ENSG00000049768 ENSG00000142082 ENSG00000283100 ENSG00000108840 ENSG00000111537 ENSG00000171720 ENSG00000147099 ENSG00000061273 ENSG00000124523 ENSG00000096717 ENSG00000089163 ENSG00000163517 PMC3808414__F8 Role of MicroRNA 1207-5P and Its Host Gene, the Long Non-Coding RNA Pvt1, as Mediators of Extracellular Matrix Accumulation in the Kidney: Implications for Diabetic Nephropathy ENSG00000140992 PMC8289466__F10 Prognostic Value and Significant Pathway Exploration Associated with TOP2A Involved in Papillary Thyroid Cancer ENSG00000142192 PMC11019597__F3 Heterologous fibrin biopolymer as an emerging approach to peripheral nerve repair: a scoping review ENSG00000134569 ENSG00000149968 ENSG00000030304 PMC5323150__F12 SIRT1-mediated FoxOs pathways protect against apoptosis by promoting autophagy in osteoblast-like MC3T3-E1 cells exposed to sodium fluoride ENSG00000116717 ENSG00000096717 PMC3745317__F1 Eicosanoid biosynthetic pathway and its activation by RTK/GFR → ERK1/2 signaling ENSG00000166278 ENSG00000146648 PMC7352599__F2 SRC constitutive activation modulates inflammation and metabolism concurring to tumor microenvironment sustainment in GBM ENSG00000291971 ENSG00000168610 PMC7059830__F1 Glycolytic-lipogenic pathway in TH17 cells ENSG00000198793 ENSG00000136997 ENSG00000113161 ENSG00000159399 ENSG00000026103 PMC9241288__F2 Application of stem cells and exosomes in the treatment of intracerebral hemorrhage: an update ENSG00000178860 ENSG00000026508 ENSG00000112715 ENSG00000171885 PMC2991775__F1 Pathways leading to the type I interferon production ENSG00000163568 ENSG00000168040 ENSG00000150455 ENSG00000276561 ENSG00000010671 ENSG00000183735 ENSG00000239732 ENSG00000088888 ENSG00000118785 ENSG00000144895 ENSG00000170458 ENSG00000189403 ENSG00000136869 ENSG00000157625 ENSG00000131323 ENSG00000135828 ENSG00000164342 PMC3186862__F1 BAD pathway in genes associated with induced cisplatin-resistance ENSG00000140992 ENSG00000002330 ENSG00000169047 ENSG00000146648 PMC5116261__F1 PI3K signaling: a molecular pathway associated with acute hypophagic response during inflammatory challenges ENSG00000171105 ENSG00000198793 ENSG00000115138 ENSG00000168610 PMC4091817__F2 The oxidative stress regulatory pathway in erythrocytes PMC5945837__F8 Galactose metabolism pathway in Streptococcus pneumoniae D39 ENSG00000069482 PMC5832136__F6 Anti-liver cancer mechanism of TF ENSG00000002330 PMC7608107__F7 A proposed working model wherein miR-210 positively regulates microglia-mediated neuroinflammation via activating the NFKB signaling pathway by targeting SIRT1 and blocking p65 deacetylation ENSG00000125538 ENSG00000096717 PMC10934612__F3 Gene regulation in fatty acid metabolism pathways by GFIPO compared to WEGG ENSG00000042832 ENSG00000138823 ENSG00000196839 ENSG00000158669 ENSG00000169710 ENSG00000198670 ENSG00000079435 PMC3406244__F3 Thyroid Hormone Receptors and Cancer ENSG00000087245 ENSG00000291971 ENSG00000198793 ENSG00000105656 ENSG00000168036 ENSG00000185591 ENSG00000100985 PMC11010636__F2 Exploring the regulatory mechanism of intestinal flora based on PD-1 receptor/ligand targeted cancer immunotherapy ENSG00000186810 ENSG00000164430 ENSG00000167207 PMC7551725__F2 Tryptophan (Trp) metabolism and AhR pathway in health and disease ENSG00000168610 ENSG00000106546 PMC3441782__F6 Molecular network of downregulated genes in U373MG cells following exposure to ET-770, the compound 1a ENSG00000169291 ENSG00000002330 ENSG00000177606 PMC3441782__F7 Molecular network of upregulated genes in U373MG cells following exposure to ET-770 derivative, the compound 3 ENSG00000145604 ENSG00000197530 ENSG00000132646 ENSG00000172005 ENSG00000123374 ENSG00000164754 ENSG00000205250 ENSG00000117399 PMC3387019__F7 Cardiac Kallikrein-Kinin System Is Upregulated in Chronic Volume Overload and Mediates an Inflammatory Induced Collagen Loss ENSG00000149968 ENSG00000130234 PMC6479968__F1 Protein C activation by the thrombin-thrombomodulin complex and the cytoprotective function of Activated Protein C (APC) in ischemic heart disease and heart failure ENSG00000134982 ENSG00000173599 PMC9244704__F10 Integrated Metabolomics and Transcriptome Analyses Unveil Pathways Involved in Sugar Content and Rind Color of Two Sugarcane Varieties ENSG00000118094 ENSG00000163754 PMC4377327__F5 Regulation of microRNA function in somatic stem cell proliferation and differentiation ENSG00000145604 ENSG00000153944 ENSG00000134215 PMC8301030__F1 Current Perspectives on the Beneficial Effects of Soybean Isoflavones and Their Metabolites for Humans ENSG00000150787 PMC4377327__F6 Regulation of microRNA function in somatic stem cell proliferation and differentiation ENSG00000084093 ENSG00000011304 ENSG00000125398 ENSG00000175215 ENSG00000198815 ENSG00000134853 ENSG00000273529 ENSG00000110693 PMC5082389__F5 IL-17 F signaling pathway is epigenetically altered in malignant COPD and non-malignant COPD lung airway epithelial cells ENSG00000148346 ENSG00000163739 ENSG00000163702 PMC8301030__F9 Current Perspectives on the Beneficial Effects of Soybean Isoflavones and Their Metabolites for Humans ENSG00000154342 ENSG00000002330 ENSG00000138798 ENSG00000168036 PMC8497904__F6 Lgr4 Regulates Oviductal Epithelial Secretion Through the WNT Signaling Pathway ENSG00000168036 ENSG00000203857 PMC3185611__F1 PRRs involved in detecting flaviviruses ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC9338538__F3 Comprehensive overview of COVID-19-related respiratory failure: focus on cellular interactions ENSG00000110799 PMC4648419__F5 Enriched pathway of Integrin (A) and migration (B) ENSG00000143799 ENSG00000178209 ENSG00000100345 ENSG00000127022 ENSG00000092820 ENSG00000213949 ENSG00000155660 ENSG00000130402 ENSG00000072110 ENSG00000171759 ENSG00000092841 ENSG00000137076 ENSG00000135424 ENSG00000138080 ENSG00000136068 PMC9083130__F7 Integrin A4 up-regulation activates the hedgehog pathway to promote arsenic and benzopyrene co-exposure-induced cancer stem cell-like property and tumorigenesis ENSG00000115232 PMC2443667__F1 Connections between the SAM cycle, transsulfuration pathway, and glutathione production ENSG00000023909 ENSG00000116761 ENSG00000116984 PMC5167048__F3 Age‐associated defects interfering with function and survival of activated T cells ENSG00000115415 ENSG00000120875 PMC7017935__F12 Antral follicle steroidogenesis ENSG00000108786 ENSG00000203857 PMC8535158__F4 NUAK Kinases: Brain–Ovary Axis ENSG00000087245 ENSG00000074590 ENSG00000100985 PMC2785127__F5 Putative targets of common changes in gene expression with single and repeated IMO stress ENSG00000227345 PMC4447104__F1 Bacteria, the ER and the Unfolded Protein Response: Friends or Foes? ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC5968105__F1 Senescence-associated secretory phenotype (SASP) is regulated by an interactive network of pathways that dictate its functional outcome ENSG00000149311 ENSG00000081041 ENSG00000148400 ENSG00000163739 ENSG00000198793 PMC5634503__F7 Proposed mechanism ENSG00000197713 PMC11904505__F3 Endometrial carcinoma (EC) cells strategically employ immune checkpoint pathways, with a notable focus on the programmed death-1 (PD-1)/programmed death-ligand 1 (PD-L1) axis PMC4245458__F2 Regulatory cross-talk between the estrogen receptor alpha and MTA family members ENSG00000057935 ENSG00000149480 PMC8773035__F1 Exosomal microRNA Differential Expression in Plasma of Young Adults with Chronic Mild Traumatic Brain Injury and Healthy Control ENSG00000071246 ENSG00000005073 ENSG00000106123 ENSG00000115268 ENSG00000164398 ENSG00000112715 PMC9408827__F3 Cartilage Oligomeric Matrix Protein, Diseases, and Therapeutic Opportunities ENSG00000139219 ENSG00000105664 ENSG00000112280 ENSG00000162551 PMC12174428__F1 IFN signaling in beta-cells and autoreactive T-cells (inset) via JAK/STAT pathway in T1D ENSG00000169245 ENSG00000159128 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000185436 ENSG00000027697 ENSG00000100219 ENSG00000162772 ENSG00000105639 PMC8313993__F1 Metabolic pathway map illustrating high-value bioactive ingredients for food, agricultural feed materials, human health, and well-being products, provided by Corynebacterium glutamicum cell factories ENSG00000197429 ENSG00000115718 PMC3814639__F2 Schematic model of the Nrf2–Keap1 signaling pathway ENSG00000178573 ENSG00000100387 ENSG00000023909 ENSG00000079999 PMC3814639__F3 Cross-talk between Nrf2 and other proteins ENSG00000254986 ENSG00000178573 ENSG00000100387 ENSG00000079999 PMC3262331__F2 Schematic signaling pathway mediated by the L-CBM complex in T and B lymphocytes.Notes: The L-CBM complex acts in the canonical NFKB (p65/p50, cRel/p50) activation pathway mediated by IKKB downstream of TCRs and BCRs ENSG00000104856 ENSG00000186716 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC3262331__F3 Schematic signaling pathway mediated by the L-CBM complex in NK cells.Notes: The L-CBM complex acts in the canonical NFKB activation pathway through activating NK cell receptors (NKR) such as Ly49H, Ly49D, NK1.1, NKG2D, FcGRIII, etc ENSG00000172936 ENSG00000141968 PMC4393718__F2 EphA/ephrinA bidirectional signalling ENSG00000070831 ENSG00000291971 ENSG00000163914 ENSG00000168610 ENSG00000126458 PMC7237878__F1 Possible associations of the renin-angiotensin system with SARS-CoV-2 infection and lung injury caused by SARS-CoV-2 ENSG00000130234 ENSG00000184012 PMC6225117__F1 Molecular mechanisms of (-)-epigallocatechingallate (EGCG) suppressing the proliferation of cervical cancer cells ENSG00000198793 ENSG00000123374 ENSG00000146648 PMC9179436__F1 Indoleamine 2, 3-Dioxygenase 1 in Regulating Tumor Microenvironment ENSG00000105397 PMC9179436__F2 Indoleamine 2, 3-Dioxygenase 1 in Regulating Tumor Microenvironment ENSG00000154342 ENSG00000049768 ENSG00000168610 ENSG00000106546 PMC3536343__F1 MTORC1 signaling to the translational machinery ENSG00000284161 ENSG00000155792 ENSG00000167658 ENSG00000179632 PMC8745410__F1 Development and Use of Akt Inhibitors in Prostate Cancer ENSG00000198793 PMC3536343__F4 MAPK signaling to the translational machinery ENSG00000284161 ENSG00000155792 ENSG00000167658 PMC4429241__F2 Signal transduction pathways activated by DNA to stimulate type I IFN expression ENSG00000159461 ENSG00000127191 ENSG00000276561 ENSG00000159714 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000082512 ENSG00000172936 ENSG00000175104 ENSG00000121060 ENSG00000184216 PMC9028356__F1 Resistance to Photodynamic Therapy (PDT) in Vulvar Cancer ENSG00000144659 ENSG00000135776 ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000256269 ENSG00000188690 ENSG00000115657 ENSG00000118777 PMC11061161__F3 Amino acid metabolism modulates T cell survival and lineage commitment ENSG00000198793 PMC7766764__F4 Regulatory network for fungal dimorphism in U ENSG00000136425 ENSG00000125686 ENSG00000172409 ENSG00000047936 ENSG00000180644 PMC9473615__F7 SAMD9 effect to DNA sensing pathway and proinflammatory responses ENSG00000164430 ENSG00000205413 PMC11061161__F1 T cell activation and subset differentiation and function by lipid metabolism ENSG00000135218 ENSG00000103569 ENSG00000168610 ENSG00000088002 ENSG00000026103 PMC10882095__F5 Immune molecule interaction network in the blood and heart tissues of chronic Chagas disease (CCC) patients ENSG00000169245 ENSG00000108691 ENSG00000111537 ENSG00000138755 PMC2575513__F2 Diversification of the innate immune arsenal in amphioxus ENSG00000167207 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000106100 ENSG00000276068 PMC4106758__F6 Visualized Gene Network Reveals the Novel Target Transcripts Sox2 and Pax6 of Neuronal Development in Trans-Placental Exposure to Bisphenol A ENSG00000106571 ENSG00000148400 ENSG00000117707 ENSG00000164690 ENSG00000112715 ENSG00000137843 PMC4429241__F4 Signal transduction pathways activated by DNA to stimulate activation of inflammasomes and the NFKB pathway ENSG00000150782 ENSG00000187796 ENSG00000163568 ENSG00000125538 PMC7662426__F3 Molecular signaling pathway of PA28G in cancer ENSG00000096717 PMC4429241__F5 Endogenous and microbial mechanisms to downmodulate and evade DNA-driven innate immune responses ENSG00000177169 ENSG00000183735 ENSG00000164430 ENSG00000105612 ENSG00000088888 ENSG00000163568 ENSG00000163565 ENSG00000121060 ENSG00000198925 PMC6608593__F4 PANTHER Pathway: an ontology-based pathway database coupled with data analysis tools PMC5570578__F7 Illustration describing the role of HPV E6/E7 oncogenes and HPV E6/E7 siRNA with cisplatin (CDDP) plus paclitaxel (PTX) therapy on HPV-infected cervical cancer cell fates ENSG00000149311 ENSG00000175054 ENSG00000123374 PMC11063389__F2 Therapeutic targets and inhibitors targeting JAK2/STAT3 signaling pathway for TNBC treatment ENSG00000291507 ENSG00000168610 PMC5369176__F1 Physiological functions of PD-related Rabs ENSG00000118508 ENSG00000084733 ENSG00000111737 PMC5361605__F4 GIST and apoptosis signaling ENSG00000132906 ENSG00000002330 ENSG00000089685 ENSG00000138794 ENSG00000120868 ENSG00000171791 ENSG00000164305 PMC7092730__F1 Three adipogenic transdifferentiation pathways ENSG00000009709 ENSG00000181090 ENSG00000111049 ENSG00000221818 ENSG00000142611 ENSG00000163132 PMC3321615__F1 Canonical and noncanonical pathways of NFKB activation ENSG00000104856 ENSG00000170458 ENSG00000136869 PMC9264937__F3 p53 Isoforms as Cancer Biomarkers and Therapeutic Targets ENSG00000051180 PMC10967338__F2 EGFR wild type and EGFRvIII mutated comparison ENSG00000163235 ENSG00000138798 ENSG00000146648 PMC7936186__F6 Schematic representation summarizing the integrated effects of PFA-enriched diets on intermediary metabolism in the broilers ENSG00000198793 ENSG00000108443 PMC10485805__F1 Intestinal flora regulates tumor microenvironment components ENSG00000136869 ENSG00000168610 ENSG00000143387 PMC10299676__F1 Mechanisms for activation of the JAK-STAT signaling pathway ENSG00000105397 ENSG00000105639 PMC10967338__F7 TGFB canonical intracellular pathways and single-domain vNAR T1 coupled to TGFB1 PMC6114229__F1 Schematic presentation of MAPK/Ras signaling pathway ENSG00000138798 ENSG00000146648 PMC10967338__F3 Therapeutic tyrosine kinase inhibitors and anti-EGFR monoclonal antibodies in glioblastoma anti-EGFR mAbs bind the EGFR extracellular domain, preventing EGFR dimerization and subsequent activation ENSG00000163235 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC10967338__F4 IL13RA1/IL4RA JAK-STAT6 pathway, IL13RA2, and single-domain vNAR coupled to IL13RA2 ENSG00000123496 ENSG00000131724 PMC10967338__F5 Allosteric inhibition of Aurora-A kinase by the vNAR-D01 intrabody ENSG00000012048 ENSG00000121068 ENSG00000138798 ENSG00000168036 ENSG00000087586 ENSG00000051180 ENSG00000168610 ENSG00000146648 ENSG00000139618 PMC7804955__F7 circNDUFB2 inhibits non-small cell lung cancer progression via destabilizing IGF2BPs and activating anti-tumor immunity ENSG00000088888 ENSG00000184995 ENSG00000276561 PMC5677022__F3 10-miRNA-score predicts defects in the HR pathway in ovarian cancer ENSG00000157764 ENSG00000178999 ENSG00000101224 ENSG00000118971 ENSG00000166851 ENSG00000139618 ENSG00000183765 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000144554 ENSG00000158636 ENSG00000134057 ENSG00000089685 ENSG00000051180 ENSG00000139687 ENSG00000196712 PMC8036376__F1 Metabolic pathway of clopidogrel and its target receptors ENSG00000165841 ENSG00000197408 ENSG00000140505 ENSG00000262243 PMC9614394__F11 Schematic mechanisms by which Wnt agonist 1 (Wnta1) regulates atrial atrial natriuretic peptide (ANP) secretion and mechanical dynamics ENSG00000071564 ENSG00000138795 ENSG00000196628 PMC8594875__F8 S-nitrosoglutathione reductase (GSNOR) deficiency accelerates cardiomyocyte differentiation of induced pluripotent stem cells ENSG00000183072 ENSG00000168036 PMC7686704__F2 Wnt–PCP signaling pathway in mammals ENSG00000070831 ENSG00000164066 ENSG00000030304 ENSG00000075275 ENSG00000112655 PMC7686704__F3 Wnt–Ca2+signaling pathway in mammals ENSG00000087095 ENSG00000171105 ENSG00000070831 ENSG00000167323 ENSG00000168036 ENSG00000109689 PMC11141153__F6 AMPK signaling pathway depicted using KEGG in tissue lysate fractionThe levels of upregulation of the proteins observed in AMPK pathway are as follows: CAB39/MO25 log2 0 ENSG00000180210 ENSG00000137713 ENSG00000171105 ENSG00000135218 ENSG00000005882 ENSG00000198793 ENSG00000135932 ENSG00000001626 ENSG00000026103 PMC7686704__F1 Canonical Wnt signaling pathway in mammals ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000141753 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000196470 ENSG00000185269 ENSG00000173273 PMC7686704__F8 Wnt signaling in breast cancer drug resistance ENSG00000165841 ENSG00000197408 ENSG00000140505 ENSG00000168036 ENSG00000118777 PMC8955684__F2 Angiopoietin-Like Protein 4 and Insulin-Like Growth Factor-1 Expression in Invasive Breast Carcinoma in Young Women ENSG00000002330 ENSG00000198793 ENSG00000154059 ENSG00000171791 ENSG00000168610 ENSG00000140443 PMC5925582__F7 Illustration of p204 function in LPS/TLR4 signaling pathway ENSG00000183735 ENSG00000170458 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC5159240__F1 Oncogenic and tumor-suppressive mouse models for breast cancer engaging HER2/neu ENSG00000284774 ENSG00000002330 ENSG00000177606 ENSG00000136997 ENSG00000152592 ENSG00000185591 PMC12026008__F2 Natural Products in the Treatment of Neuroinflammation at Microglia: Recent Trend and Features ENSG00000198793 ENSG00000136869 ENSG00000079999 PMC4208300__F3 Simplified outline of the MyD88-signaling pathway by which TLR agonists induce the production of inflammatory mediators ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000140577 ENSG00000175104 PMC5949249__F1 To Eat or Not to Eat – The Metabolic Flavor of Ferroptosis ENSG00000135423 ENSG00000196839 ENSG00000167468 ENSG00000072274 ENSG00000145321 ENSG00000111371 PMC5809773__F2 Biosynthesis of galactolipids in the chloroplast envelope membranes in Arabidopsis ENSG00000069482 PMC3175721__F6 Models for context-dependent ICL repair during replication ENSG00000276787 ENSG00000100625 PMC3874238__F2 Insulin is the major hormone controlling critical energy functions such as glucose and lipid metabolism ENSG00000002330 ENSG00000010810 ENSG00000101440 ENSG00000106070 ENSG00000169047 PMC4114929__F3 Importance of RhoGTPases in formation, characteristics, and functions of invadosomes ENSG00000070831 PMC11928533__F3 Diverse biological functions of the CRIP family ENSG00000182809 ENSG00000103266 ENSG00000111537 ENSG00000134982 ENSG00000163739 ENSG00000198793 ENSG00000177556 ENSG00000168036 ENSG00000213145 ENSG00000129151 ENSG00000026103 ENSG00000150630 PMC8904073__F7 Dickkopf-3 and Beta-catenin play opposite roles in the Wnt/Beta-catenin pathway during the abnormal subchondral bone formation of human knee osteoarthritis ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000050165 ENSG00000168036 PMC4870363__F1 Schematic overview of TLR signaling pathway in neutrophilic and eosinophilic asthma ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC8227265__F1 Enhancing Sesquiterpenoid Production from Methane via Synergy of the Methylerythritol Phosphate Pathway and a Short-Cut Route to 1-Deoxy-D-xylulose 5-Phosphate in Methanotrophic Bacteria ENSG00000122966 ENSG00000172005 ENSG00000197429 ENSG00000284194 PMC4439431__F1 Metabolism of a resting uninfected cell ENSG00000131473 ENSG00000113161 ENSG00000169710 PMC6763723__F1 VLC-SFA and VLC-PUFA elongation pathways ENSG00000118402 ENSG00000119915 ENSG00000170522 ENSG00000066322 ENSG00000197977 PMC4439431__F2 Metabolism of a cell infected by HCMV ENSG00000131473 ENSG00000113161 ENSG00000169710 PMC4439431__F3 Metabolism of a macrophage activated by immune signals ENSG00000131473 ENSG00000113161 ENSG00000169710 PMC7982634__F3 Natural extracts exert inhibitory effects on PI3 K/Akt signaling pathway ENSG00000132906 ENSG00000002330 ENSG00000285109 PMC7982634__F4 Natural extracts block NF‐KB signaling pathway ENSG00000102871 ENSG00000172936 ENSG00000130159 ENSG00000127191 PMC7982634__F1 Natural extracts can induce apoptosis through ERS pathway and mitochondrial pathway ENSG00000291983 ENSG00000128272 PMC7340679__F1 Anticancer activity of mistletoe ENSG00000135446 ENSG00000123374 ENSG00000171791 PMC11728246__F2 TRAPPC4 and TRAPPC9 in cell signaling ENSG00000104856 ENSG00000167632 ENSG00000280495 PMC11118191__F2 Overview of USP36-mediated signaling pathways ENSG00000143799 ENSG00000114416 ENSG00000055483 ENSG00000182923 ENSG00000150457 ENSG00000131023 ENSG00000159399 PMC7470069__F5 Mercury-sulfhydryl-dependent effects on apoptosis regulation ENSG00000171791 ENSG00000079999 PMC2713245__F1 Signal transduction through activin receptors ENSG00000137834 ENSG00000135414 ENSG00000168036 PMC8393314__F1 Glycosylation in Melanoma Progression ENSG00000167601 ENSG00000042832 ENSG00000285222 ENSG00000076706 ENSG00000070731 ENSG00000115525 ENSG00000126091 ENSG00000073849 ENSG00000122194 ENSG00000140297 ENSG00000180210 ENSG00000069482 ENSG00000196371 ENSG00000146648 PMC7340679__F7 Probable mechanism of antiobesity activity of mistletoe ENSG00000026103 PMC7396059__F3 NKG2D signaling pathways ENSG00000099942 ENSG00000141968 PMC6533528__F7 Schematic model of IL‐1B‐ and Fn‐fs‐mediated ADAMTS‐12 and ‐7 stimulation by Runx2 and Wnt/B‐catenin signalling modulation in OA‐SF ENSG00000105664 ENSG00000134982 ENSG00000188064 ENSG00000125538 ENSG00000168036 ENSG00000151388 PMC7396059__F2 Signaling pathways by NCRs ENSG00000213658 ENSG00000134215 ENSG00000160293 ENSG00000141968 PMC6769516__F5 Pathway of the investigated genes involved in apoptosis ENSG00000132906 ENSG00000120833 ENSG00000002330 ENSG00000115415 ENSG00000168040 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC7940844__F1 Toll-like receptor 9 (TLR9) signaling pathway(s) upon CpG oligodeoxynucleotides (CpG-ODN) stimulation: CpG-ODN is internalized through endosomes where it interacts with the endosomic domain of TLR9 ENSG00000239732 ENSG00000125538 ENSG00000136869 ENSG00000276561 PMC5431817__F4 Summary of the main effects of diabetes and NRG1 treatment in gastrocnemius muscle ENSG00000135218 ENSG00000178568 ENSG00000106459 PMC2172299__F8 A hypothetical model showing the roles of Fak and paxillin in motile HeLa cells ENSG00000170558 PMC8002185__F3 Serine/glycine biosynthesis pathway activation in tumor treatment resistance ENSG00000284320 ENSG00000128272 ENSG00000157764 ENSG00000092621 ENSG00000136997 ENSG00000135069 ENSG00000146733 ENSG00000146648 PMC8664605__F6 Integrative Analysis of DNA Methylation and Gene Expression Profiling Data Reveals Candidate Methylation-Regulated Genes in Hepatoblastoma ENSG00000149311 ENSG00000175054 ENSG00000179091 ENSG00000132646 ENSG00000198793 ENSG00000136997 ENSG00000042286 ENSG00000123374 ENSG00000112378 ENSG00000164305 ENSG00000026103 ENSG00000093009 PMC5704042__F2 Structure of SCF/c-KIT proteins and downstream signalling pathways ENSG00000112576 ENSG00000002330 ENSG00000291971 ENSG00000198793 ENSG00000123374 PMC8002185__F1 Serine/glycine biosynthesis pathway activation in cancer ENSG00000284320 ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC4936987__F4 Pathway diagram of the genes in the tricarboxylic acid cycle ENSG00000100412 ENSG00000105953 ENSG00000091140 PMC9332011__F1 Hsp90 and Associated Co-Chaperones of the Malaria Parasite ENSG00000105401 PMC8002185__F4 Linking radiotherapy resistance and serine/glycine metabolism in the tumor and associated tumor microenvironment ENSG00000092621 ENSG00000125538 ENSG00000135069 ENSG00000146733 PMC4651103__F1 Working figure of the angiogenesis pathway genes ENSG00000125538 ENSG00000169047 ENSG00000128052 ENSG00000122877 ENSG00000146648 PMC4936987__F2 Pathway diagram of the glycolysis pathway ENSG00000262785 ENSG00000143158 ENSG00000074800 ENSG00000173599 ENSG00000146701 ENSG00000136872 ENSG00000091140 ENSG00000159399 ENSG00000152556 PMC8940980__F1 SARS-CoV-2 Infection: Host Response, Immunity, and Therapeutic Targets ENSG00000162711 ENSG00000130234 ENSG00000184012 ENSG00000172936 PMC8818156__F8 CENPF/CDK1 signaling pathway enhances the progression of adrenocortical carcinoma by regulating the G2/M-phase cell cycle ENSG00000117724 ENSG00000134057 PMC12249078__F3 Molecular mechanisms lead to uterine fibrosis ENSG00000198793 ENSG00000168036 PMC7457002__F5 ATF3 plays a vital role in breast cancer ENSG00000113384 ENSG00000162772 PMC3992244__F2 Dietary and Metabolic Control of Stem Cell Function in Physiology and Cancer ENSG00000127837 ENSG00000198793 ENSG00000164327 ENSG00000096717 PMC3992244__F3 Dietary and Metabolic Control of Stem Cell Function in Physiology and Cancer PMC7029724__F4 Patient‐specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies ENSG00000140992 ENSG00000002330 ENSG00000006712 ENSG00000134982 ENSG00000138798 ENSG00000146648 PMC8856111__F1 CounterAKTing HIV: Toward a “Block and Clear” Strategy? ENSG00000198793 ENSG00000074319 ENSG00000049768 ENSG00000121966 PMC6602147__F10 Proposed schematic mechanism of EBV-associated gastric carcinogenesis via the activation of the PI3K/AKT/mTOR pathway, and its blockade by CMG002 ENSG00000198793 ENSG00000105656 PMC6106977__F1 MiR-30a significantly inhibits cell proliferation ENSG00000147649 ENSG00000100934 ENSG00000009335 ENSG00000198176 ENSG00000134057 ENSG00000143476 ENSG00000132383 ENSG00000124766 ENSG00000064655 ENSG00000168036 ENSG00000162772 PMC9703992__F6 Cub pathway ENSG00000104856 ENSG00000140564 ENSG00000173039 ENSG00000146648 ENSG00000126458 PMC6106977__F2 MiR-30a significantly promotes cell apoptosis by regulating several relevant effectors ENSG00000147649 ENSG00000132383 PMC5116300__F2 Eosinophils and Mast Cells in Aspirin-Exacerbated Respiratory Disease ENSG00000226275 ENSG00000113520 PMC8323701__F1 Dehydroepiandrosterone sulfate as a scavenging antioxidant: the evidence from Caenorhabditis elegans’ nervous system under hypoxia PMC8071069__F5 FoxO signaling pathway and Glycolysis/Gluconeogenesis pathway ENSG00000103479 ENSG00000099860 ENSG00000124253 PMC2834467__F2 Map showing relationship between genes positively correlated with plasma estradiol superimposed on Ingenuity map ENSG00000167772 ENSG00000143126 PMC9331192__F2 Chicken Prolactin, Growth Hormone and Their Receptors in the Immune System ENSG00000112964 PMC6080611__F2 Molecular regulation in autophagy ENSG00000198793 PMC8139665__F9 TLR3 Activation by Zika Virus Stimulates Inflammatory Cytokine Production Which Dampens the Antiviral Response Induced by RIG-I-Like Receptors ENSG00000115415 ENSG00000168610 ENSG00000164342 PMC3814227__F2 Autophagy: regulation ENSG00000169047 ENSG00000096717 PMC8799091__F5 Identification of significant genes in non-small cell lung cancer by bioinformatics analyses ENSG00000177455 ENSG00000002330 ENSG00000179091 ENSG00000186716 ENSG00000163914 ENSG00000111816 PMC9033806__F8 Schematic model illustrates the potential mechanisms by which GXYLT1 and GXYLT1S212* promote the metastasis of CRC ENSG00000172986 ENSG00000151233 ENSG00000114315 ENSG00000146648 PMC3425953__F1 Activity of Wnt canonical signaling pathway in the normal and tumor cells ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000132693 PMC3425953__F2 The activity of the EGFR/KRAS signaling pathway in normal and tumor cells ENSG00000157764 ENSG00000146648 PMC3425953__F3 The activity of PI3K signaling pathway in normal and tumor cells ENSG00000198793 ENSG00000146648 PMC12170841__F1 Action of sEVs in promoting SC regeneration after SCI: (1) The sEVs alleviate symptoms by modulating the neuroinflammatory response to SCI ENSG00000242689 ENSG00000074319 ENSG00000110651 ENSG00000113520 ENSG00000010278 ENSG00000135404 PMC11599795__F2 In bladder cancer, YAP1 activity is regulated by YAP1 gene expression, post-transcriptional mRNA modifications, and the activity of the Hippo signaling pathway ENSG00000150457 ENSG00000131023 PMC11599795__F1 Hippo signaling pathway is a key regulator of cellular and systemic metabolism, maintaining organ size and tissue homeostasis by controlling cell proliferation, survival and regeneration ENSG00000150457 ENSG00000131023 PMC8732359__F1 LncRNA Expression Profiles in Systemic Lupus Erythematosus and Rheumatoid Arthritis: Emerging Biomarkers and Therapeutic Targets ENSG00000115884 ENSG00000167207 ENSG00000198793 ENSG00000135114 ENSG00000166793 ENSG00000111331 PMC9695301__F3 Recent Progress in Research on Mechanisms of Action of Natural Products against Alzheimer’s Disease: Dietary Plant Polyphenols ENSG00000125538 ENSG00000136869 ENSG00000121807 PMC3671665__F1 Targeting the Sonic hedgehog signaling pathway by compounds and derivatives from natural products ENSG00000164690 ENSG00000128602 PMC10671441__F8 S-Adenosylhomocysteine Hydrolase Downregulation on Wnt Signaling Pathway in SW480 Cells ENSG00000019991 ENSG00000101751 ENSG00000136997 ENSG00000108342 ENSG00000171791 ENSG00000175336 ENSG00000026103 PMC10671441__F9 Human Embryonic Stem Cell Pluripotency Signaling ENSG00000084093 ENSG00000107404 ENSG00000136997 ENSG00000156574 ENSG00000164362 ENSG00000135111 ENSG00000128342 ENSG00000119715 ENSG00000121570 PMC5100803__F1 Genes associated with the NRF2-mediated oxidative stress response pathway that were differentially regulated in aldosterone-producing adenoma (APA) vs zona glomerulosa (ZG) and ZG vs zona fasciculata (ZF) ENSG00000174156 ENSG00000170899 ENSG00000027075 ENSG00000073060 ENSG00000138356 ENSG00000168765 ENSG00000079999 PMC10671441__F4 IPA Core analysis of the Epithelial Adherens Junctions Signaling in SW480 AHCY deficient cells with increased expression of LEF1 protein ENSG00000110237 ENSG00000019991 ENSG00000006607 ENSG00000177485 ENSG00000175866 ENSG00000114346 ENSG00000130396 ENSG00000188613 ENSG00000140575 ENSG00000138798 ENSG00000170558 ENSG00000138071 ENSG00000160007 ENSG00000112290 ENSG00000186575 ENSG00000124216 ENSG00000156299 ENSG00000010810 ENSG00000019549 ENSG00000015285 ENSG00000077782 ENSG00000146648 ENSG00000140443 PMC10671441__F2 Wnt Signaling pathway ENSG00000087095 ENSG00000166167 ENSG00000156076 ENSG00000135100 ENSG00000134982 ENSG00000168036 ENSG00000104332 ENSG00000135341 ENSG00000196628 ENSG00000104814 ENSG00000177606 ENSG00000136997 ENSG00000115266 ENSG00000026508 ENSG00000168646 PMC6917725__F10 Sexual dimorphism and the role of estrogen in the immune microenvironment of liver metastases ENSG00000102871 ENSG00000168040 PMC8914339__F1 Insights Into Ferroptosis, a Novel Target for the Therapy of Cancer ENSG00000115107 ENSG00000079999 PMC8914339__F2 Insights Into Ferroptosis, a Novel Target for the Therapy of Cancer ENSG00000167468 ENSG00000111684 PMC10341343__F2 Glucose metabolism in cancer cells ENSG00000180210 ENSG00000092621 ENSG00000114268 PMC9101486__F6 High-Fat Diet Induces Low-Grade Cochlear Inflammation in CD-1 Mice ENSG00000172936 ENSG00000157625 ENSG00000162692 ENSG00000175104 ENSG00000127191 PMC6652202__F4 Protein-protein interaction network ENSG00000139546 PMC8628183__F1 ER signaling mechanisms ENSG00000291971 PMC5501721__F1 Extracellular nutrients are required to maintain oncogenic signaling in brain cancer – a critical role for mTORC2 ENSG00000121879 PMC8981655__F3 m6A binding protein YTHDF2 in cancer ENSG00000120833 ENSG00000198492 ENSG00000198793 ENSG00000010818 ENSG00000107902 ENSG00000168036 ENSG00000150687 ENSG00000162191 ENSG00000112715 ENSG00000120162 ENSG00000167034 ENSG00000136826 ENSG00000145391 ENSG00000136997 ENSG00000179094 ENSG00000104081 PMC8981655__F4 m6A binding protein YTHDF2 in cancer ENSG00000176692 ENSG00000198492 ENSG00000100146 ENSG00000146648 ENSG00000121966 ENSG00000123908 PMC9597993__F2 Immune checkpoint of B7-H3 in cancer: from immunology to clinical immunotherapy ENSG00000134982 ENSG00000166278 ENSG00000168610 ENSG00000162892 ENSG00000174564 ENSG00000142224 ENSG00000016402 PMC7722523__F1 Molecular Pathway Activation Downstream of BCR-ABL1 ENSG00000033327 ENSG00000186716 ENSG00000198793 ENSG00000168036 ENSG00000099942 ENSG00000128602 PMC4007780__F1 CADBIOM model for the canonical TGFB pathway ENSG00000042832 PMC6312894__F1 From Bench to Clinic: the Potential of Therapeutic Targeting of the IL-22 Signaling Pathway in Atopic Dermatitis ENSG00000162594 ENSG00000136869 ENSG00000115009 ENSG00000112486 PMC6434849__F7 Interesting putative mechanisms are identified by iPathwayGuide (www.advaitabio.com) on the Glutamatergic synapse and the Chemokine signaling pathways ENSG00000120885 ENSG00000119912 ENSG00000102003 PMC8042267__F3 IL23 in the development and activation of Th17 cells ENSG00000162594 ENSG00000112115 PMC4786287__F1 Altering the Mitochondrial Fatty Acid Synthesis (mtFASII) Pathway Modulates Cellular Metabolic States and Bioactive Lipid Profiles as Revealed by Metabolomic Profiling ENSG00000255154 ENSG00000176715 PMC8042267__F4 Therapeutic approaches targeting IL23 and IL17 signaling ENSG00000162594 ENSG00000096996 ENSG00000112115 PMC12251195__F2 Programmed cell death protein 1/programmed death-ligand 1 (PD-1/PD-L1)-mediated immune evasion in the tumor microenvironment ENSG00000089692 PMC6445045__F1 Schematic representation of the unfolded protein response (UPR) ENSG00000128272 ENSG00000185591 ENSG00000100219 ENSG00000167182 PMC8042267__F1 IL23 signaling in Crohn’s disease ENSG00000162594 ENSG00000096996 ENSG00000138378 ENSG00000112115 ENSG00000168610 PMC8042267__F2 IL23 mediated resistance to apoptosis of mucosal CD4+ T cells in anti-TNF refractory Crohn’s disease patients ENSG00000162594 ENSG00000168610 PMC11551676__F1 Wnt signaling pathway ENSG00000111537 ENSG00000134982 ENSG00000168036 PMC11641910__F1 Network of protein interactions involving p21 in diverse cellular processes ENSG00000132646 ENSG00000074319 ENSG00000168610 PMC11641910__F2 Various metabolic pathways involving p21 ENSG00000138798 ENSG00000078237 ENSG00000146648 ENSG00000166592 PMC4663607__F1 Effects of vitamin K antagonists and direct oral anticoagulants on coagulation ENSG00000180210 PMC9000741__F2 Extracellular HSPs: The Potential Target for Human Disease Therapy ENSG00000170458 ENSG00000164136 ENSG00000136869 PMC3606632__F6 MTOR signaling pathway in KEGG pathway analysis ENSG00000157764 ENSG00000198793 ENSG00000164327 PMC7352604__F4 Wt TP53 LUAD females are enriched in antigen processing and presentation pathways with links to longevity ENSG00000103811 ENSG00000157303 ENSG00000111537 ENSG00000127022 ENSG00000273686 ENSG00000231925 PMC102215__F1 Pathways to Lignin Monomers.The “metabolic grid” shown in this scheme incorporates the results of recent studies suggesting previously unexpected substrate specificities for F5H and COMT (; ; ) ENSG00000100473 ENSG00000084774 PMC5179106__F3 A) Protein-protein interaction analysis of 524 AD-related proteins revealed two large protein clusters: the APP network (14 yellow nodes) and the CAD network (11 red nodes) ENSG00000198380 ENSG00000084774 PMC9550168__F6 SGLT2 inhibitors suppress epithelial–mesenchymal transition in podocytes under diabetic conditions via downregulating the IGF1R/PI3K pathway ENSG00000169554 ENSG00000124216 ENSG00000140443 PMC7868988__F1 The main cellular pathways regulated by NNMT ENSG00000105835 ENSG00000096717 PMC1475580__F1 Sequence of events in ATM→ ATR dependent signaling of DSBs in S/G2 cells ENSG00000149311 ENSG00000175054 ENSG00000164053 PMC5593528__F8 Loss of p16INK4A stimulates aberrant mitochondrial biogenesis through a CDK4/Rb-independent pathway ENSG00000135446 ENSG00000105810 PMC6256083__F5 Proposed anti-inflammatory pathway of beauvericin (BEA) in macrophages (adapted from Yoo et al., ) ENSG00000291971 ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC10495754__F1 RIPK3-CaMKII-mPTP signaling pathway ENSG00000137275 ENSG00000102871 ENSG00000156026 ENSG00000198626 ENSG00000100504 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC7343132__F6 Comprehensive RNA-Seq profiling of the lung transcriptome of Bashbay sheep in response to experimental Mycoplasma ovipneumoniae infection ENSG00000125538 ENSG00000172936 ENSG00000184216 PMC7343132__F3 Comprehensive RNA-Seq profiling of the lung transcriptome of Bashbay sheep in response to experimental Mycoplasma ovipneumoniae infection ENSG00000135218 ENSG00000144410 ENSG00000170458 ENSG00000168040 ENSG00000150455 ENSG00000175104 PMC2375600__F2 From feeding one to feeding many: hormone-induced changes in bodyweight homeostasis during pregnancy ENSG00000150907 ENSG00000168610 PMC10981749__F8 Model for the induction of proinflammatory SASP by typhoid toxin ENSG00000150782 ENSG00000183735 ENSG00000164430 ENSG00000144895 ENSG00000162772 ENSG00000142166 PMC3412720__F3 JAK-STAT signaling pathway ENSG00000112576 ENSG00000213928 ENSG00000005339 ENSG00000164056 ENSG00000119535 ENSG00000114737 ENSG00000136997 ENSG00000137193 ENSG00000187266 ENSG00000118971 PMC8534790__F5 Review of Bioeffects of Static Magnetic Fields on the Oral Tissue-Derived Cells and Its Application in Regenerative Medicine ENSG00000154678 ENSG00000168036 ENSG00000108821 ENSG00000131196 PMC3412720__F4 AKT signaling pathway ENSG00000140992 ENSG00000100906 ENSG00000109320 ENSG00000269335 ENSG00000213341 PMC6046223__F8 Signaling pathway which miR-21 can regulate multiple functions in astrocytes ENSG00000198793 PMC7762545__F4A Genomic Fabric Remodeling in Metastatic Clear Cell Renal Cell Carcinoma (ccRCC): A New Paradigm and Proposal for a Personalized Gene Therapy Approach ENSG00000132906 ENSG00000142192 ENSG00000002330 ENSG00000070831 ENSG00000291971 ENSG00000105647 ENSG00000169032 ENSG00000112715 ENSG00000121879 ENSG00000073756 ENSG00000089159 ENSG00000120910 ENSG00000221823 ENSG00000117020 ENSG00000063176 ENSG00000169750 ENSG00000129946 ENSG00000128052 ENSG00000166501 ENSG00000197943 ENSG00000171608 PMC8658239__F2 Important Role of Endothelium and Extracellular Vesicles in the Cellular Mechanism of Aortic Aneurysm Formation ENSG00000162692 ENSG00000127191 PMC3057454__F2 Autophagy in Immunity and Cell-Autonomous Defense Against Intracellular Microbes ENSG00000177169 ENSG00000198793 ENSG00000070540 ENSG00000157954 PMC2925029__F3 The IFN-λ receptor signaling pathway ENSG00000105397 ENSG00000115415 ENSG00000157601 ENSG00000147896 ENSG00000142166 PMC7506081__F2 Sterol regulatory element-binding protein (SREBPs) mediate the uptake, efflux, and storage of cholesterol ENSG00000130164 ENSG00000160179 ENSG00000026103 PMC2168342__F7 Matrilysin and stromelysin-2 differentially control apoptotic transcriptional response ENSG00000104884 ENSG00000002330 ENSG00000151929 ENSG00000171791 ENSG00000135341 ENSG00000112715 ENSG00000164305 ENSG00000064300 ENSG00000115317 ENSG00000136997 ENSG00000164400 ENSG00000107731 ENSG00000101191 ENSG00000090376 ENSG00000104081 ENSG00000100065 ENSG00000293532 ENSG00000026103 ENSG00000189067 ENSG00000023445 ENSG00000184990 ENSG00000142192 ENSG00000170027 ENSG00000143878 ENSG00000137275 ENSG00000064393 ENSG00000196954 ENSG00000166670 ENSG00000168040 ENSG00000291983 ENSG00000173757 ENSG00000134070 ENSG00000164754 PMC11004224__F7 PM2.5, component cause of severe metabolically abnormal obesity: An in silico, observational and analytical study ENSG00000134086 ENSG00000111537 ENSG00000136869 PMC7506081__F3 Sterol regulatory element-binding protein (SREBPs) is involved in the activation of M1-type macrophages ENSG00000131473 ENSG00000108691 ENSG00000172936 ENSG00000136869 PMC7506081__F4 In tumor cells, the glucose uptake is significantly increased ENSG00000131473 ENSG00000147162 ENSG00000130164 ENSG00000150907 ENSG00000198793 ENSG00000169710 ENSG00000168610 ENSG00000079999 PMC11004224__F5 PM2.5, component cause of severe metabolically abnormal obesity: An in silico, observational and analytical study ENSG00000150991 ENSG00000100979 PMC4697149__F1 Enhanced inflammatory gene expression by IL1B; feedback control by DUSP1 and feed-forward control by ZFP36 ENSG00000128016 ENSG00000125538 PMC11004224__F8 KEGG network diagram of cytokine-cytokine receptor interactionLarge white box: biological pathway map ENSG00000143185 ENSG00000226275 ENSG00000122756 PMC6214980__F7 Sex-associated function of epithelial STAT3 signaling in K-ras mutant lung cancer ENSG00000108702 ENSG00000108691 ENSG00000163739 ENSG00000118520 ENSG00000168610 PMC8507033__F4 Preliminary construction of a regulatory network of miRNAs in the pathogenesis of nucleus pulposus degeneration - a review based on data mining ENSG00000136869 ENSG00000175104 ENSG00000168610 ENSG00000184216 PMC5781259__F2 Construction and analysis of the HEV-host PPI network ENSG00000130741 ENSG00000145191 ENSG00000198692 ENSG00000120705 ENSG00000173674 ENSG00000111361 ENSG00000284161 ENSG00000172239 ENSG00000167658 ENSG00000243056 ENSG00000156976 ENSG00000189369 ENSG00000100664 ENSG00000148730 ENSG00000187840 ENSG00000161960 ENSG00000086232 ENSG00000070756 ENSG00000283391 ENSG00000128829 ENSG00000118898 ENSG00000101210 PMC8507033__F2 Preliminary construction of a regulatory network of miRNAs in the pathogenesis of nucleus pulposus degeneration - a review based on data mining ENSG00000121297 ENSG00000128710 ENSG00000150907 ENSG00000198793 ENSG00000167658 PMC8507033__F3 Preliminary construction of a regulatory network of miRNAs in the pathogenesis of nucleus pulposus degeneration - a review based on data mining ENSG00000150907 ENSG00000198793 ENSG00000175104 ENSG00000168610 ENSG00000184216 PMC8102118__F6 Cell Division Autoantigen 1 (CDA1) in Renal Fibrosis of Diabetic Nephropathy PMC11621219__F4 Immunostimulants regulating adaptive immune responses by activating TLRs ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000276561 ENSG00000164342 PMC12012963__F1 Simplified schematic of de novo nucleotide synthesis ENSG00000102967 ENSG00000084774 PMC5486142__F2 Adiponectin signal transduction implicating a cross talk with the insulin signaling pathway: Insulin and adiponectin interact with their respective receptors, which trigger a cascade of signaling events ENSG00000157500 ENSG00000159346 ENSG00000285070 PMC6360685__F2 The mechanism of miR-34 in EMT ENSG00000138795 ENSG00000168036 ENSG00000168610 ENSG00000198625 PMC6534557__F5 Directed acyclic graph (DAG) of the 10 most enriched Gene Ontology (GO) terms and cytokine–cytokine receptor interaction pathways based on KEGG analysis ENSG00000181026 PMC5039587__F1 Toll-like receptor 4 (TLR4) signaling pathway in porcine intestinal epithelial (PIE) cells ENSG00000170458 ENSG00000177606 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000185187 ENSG00000175104 PMC4255921__F1 Canonical and non-canonical TGFB signaling ENSG00000113360 PMC5039587__F2 Toll-like receptor 4 (TLR4) signaling pathway in porcine intestinal epithelial (PIE) cells by acidic (APS) and neutral (NPS) exopolysaccharides produced by Lactobacillus plantarum N14 and Lactobacillus delbrueckii TUA4408L ENSG00000170458 ENSG00000177606 ENSG00000172005 ENSG00000214285 ENSG00000134070 ENSG00000157625 ENSG00000136869 ENSG00000185187 ENSG00000175104 PMC3134613__F6 Specificity in neuronal activity-regulated gene transcription ENSG00000016490 ENSG00000133216 PMC11186373__F8 Sodium chloride promotes macrophage pyroptosis and aggravates rheumatoid arthritis by activating SGK1 through GABA receptors Slc6a12 ENSG00000278718 ENSG00000118515 ENSG00000111181 PMC3035094__F6 Cic regulatory elements mediate Torso and EGFR responses ENSG00000042832 ENSG00000079432 ENSG00000146648 PMC3285553__F3 Additional mechanisms by which Wnt/Beta-catenin signaling can be modulated in cancer ENSG00000019991 ENSG00000148400 ENSG00000134982 ENSG00000168036 ENSG00000128602 PMC3285553__F4 Schematic illustrating numerous small molecules and biological compounds identified in the literature that inhibit Wnt/Beta-catenin signaling at various points in the pathway ENSG00000134982 ENSG00000050165 ENSG00000168036 ENSG00000106483 ENSG00000177283 ENSG00000155760 PMC4878148__F1 Genomic Landscape of Response to EGFR Blockade in Colorectal Cancer ENSG00000157764 ENSG00000134853 ENSG00000146648 PMC6801973__F3 Entamoeba sulfolipid metabolism ENSG00000168066 PMC9641939__F6 Effects and related mechanism of alpha-adrenergic receptor inhibitor phentolamine in a rabbit model of acute pulmonary embolism combined with shock PMC4231433__F1 Wired on sugar: the role of the CNS in the regulation of glucose homeostasis ENSG00000110711 ENSG00000198793 ENSG00000115138 ENSG00000166603 PMC11141639__F1 Winer et al ENSG00000136997 ENSG00000166851 PMC5526760__F5 Summary of gene function and epistatic interaction of the IL-10/STAT3 signaling pathway in pediatric inflammatory bowel disease ENSG00000105397 ENSG00000243646 ENSG00000110324 ENSG00000168610 PMC2674015__F2A Toll-like Receptors: Novel Pharmacological Targets for the Treatment of Neurological Diseases ENSG00000183735 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC8050341__F3 Lactate and amino acid metabolism in Tregs ENSG00000081181 ENSG00000135218 ENSG00000122966 ENSG00000148942 ENSG00000049768 ENSG00000115419 ENSG00000106546 ENSG00000167701 PMC2657110__F2 HIV-1 modulates the interferon-induced antiviral host mechanisms, protein kinase R and 2',5'-oligoadenylate synthesis ENSG00000135828 PMC8050341__F1 Mitochondria and fatty acid metabolism in Tregs ENSG00000131473 ENSG00000074800 ENSG00000166278 ENSG00000049768 ENSG00000026103 PMC4825590__F1 Crosstalk between cell cycle regulators and cellular metabolism ENSG00000134982 ENSG00000135446 ENSG00000105810 PMC7609160__F1 Hippo Signal Transduction Mechanisms in T Cell Immunity ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000150907 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC6177401__F4 Dengue virus and the host innate immune response ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000113360 ENSG00000164342 PMC6177401__F5 Dengue virus and the host innate immune response ENSG00000105397 ENSG00000115415 ENSG00000127481 ENSG00000182326 ENSG00000236625 PMC6177401__F2 Innate immune response to DENV infection ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000113360 PMC4364715__F4 Novel Genetic Locus Implicated for HIV-1 Acquisition with Putative Regulatory Links to HIV Replication and Infectivity: A Genome-Wide Association Study ENSG00000070601 ENSG00000171791 PMC6177401__F3 Dengue virus and the host innate immune response ENSG00000039537 ENSG00000213928 ENSG00000113600 ENSG00000105397 ENSG00000115415 ENSG00000136869 ENSG00000236625 PMC3597092__F3 Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR ENSG00000276559 ENSG00000167910 ENSG00000156096 ENSG00000026103 PMC3493824__F1 Cellular Targeting in Autoimmunity PMC3493824__F2 Cellular Targeting in Autoimmunity PMC2583357__F1 ALTERATION OF AKT ACTIVITY INCREASES CHEMOTHERAPEUTIC DRUG AND HORMONAL RESISTANCE IN BREAST CANCER YET CONFERS AN ACHILLES HEEL BY SENSITIZATION TO TARGETED THERAPY ENSG00000002330 ENSG00000108557 ENSG00000291971 ENSG00000198793 ENSG00000177606 PMC2583357__F3 ALTERATION OF AKT ACTIVITY INCREASES CHEMOTHERAPEUTIC DRUG AND HORMONAL RESISTANCE IN BREAST CANCER YET CONFERS AN ACHILLES HEEL BY SENSITIZATION TO TARGETED THERAPY ENSG00000062485 PMC5839390__F6 NFAT-mediated defects in erythropoiesis cause anemia in Il2−/− mice ENSG00000105610 ENSG00000187266 ENSG00000131196 PMC11354414__F3 Cell signaling pathway involving TNFA in activating NFKB ENSG00000183735 ENSG00000137275 PMC9685446__F9 Fatty Liver/Adipose Tissue Dual‐Targeting Nanoparticles with Heme Oxygenase‐1 Inducer for Amelioration of Obesity, Obesity‐Induced Type 2 Diabetes, and Steatohepatitis ENSG00000042832 ENSG00000169710 ENSG00000096717 PMC11546156__F1 Brief molecular mechanisms of the autophagy signaling pathway ENSG00000177169 ENSG00000152348 ENSG00000198382 ENSG00000083290 ENSG00000126775 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC11718791__F1 PI3K pathway and FDA-approved, or fast-track designation-granted PI3K inhibitors PMC11718791__F2 PI3K, cell cycle, and ER pathways crosstalk in HR+ HER- BC ENSG00000135446 ENSG00000105810 PMC6785146__F3 Mechanism of alterations in the TSPO-mediated mitophagic signaling pathway and NLRP3 inflammasome activation in bipolar disorder ENSG00000150782 ENSG00000125538 ENSG00000158828 ENSG00000168610 PMC8417405__F2 Interactions Between Genes From Aging Pathways May Influence Human Lifespan and Improve Animal to Human Translation ENSG00000149311 ENSG00000175054 PMC5183627__F1 TGR5 regulates different cell signaling pathways ENSG00000104321 ENSG00000078747 ENSG00000163914 ENSG00000168610 PMC6908786__F4 Different signaling pathways triggered by different iNOS inducers that regulate iNOS expression (left: activation of NFKB pathway; right: activation of JAK/STAT-1A pathway) ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC5334258__F3 Trafficking pathways of E-cadherin ENSG00000069329 ENSG00000028528 ENSG00000163072 PMC3782064__F2 Ingenuity pathway analysis ENSG00000171311 ENSG00000090061 ENSG00000284774 ENSG00000118007 ENSG00000275700 ENSG00000085514 ENSG00000121716 ENSG00000151835 ENSG00000153914 ENSG00000188229 ENSG00000278574 ENSG00000178445 ENSG00000245848 ENSG00000153879 ENSG00000204520 ENSG00000109670 ENSG00000081237 ENSG00000092199 ENSG00000277641 ENSG00000292348 ENSG00000158270 ENSG00000131323 ENSG00000066427 ENSG00000089902 ENSG00000127863 ENSG00000099899 PMC7247259__F1 Biogenesis, structure, release, and uptake of exosomes ENSG00000135404 PMC8933076__F1 Review of Bile Acid Metabolism and Signaling in Cognitive Dysfunction-Related Diseases ENSG00000167910 ENSG00000180432 ENSG00000099377 ENSG00000115271 ENSG00000135929 PMC9068303__F8 N-((1-(4-Fluorophenyl)-1H-1,2,3-triazol-4-yl)methyl)-2-methylene-3-oxo-olean-12-en-28-amide Induces Apoptosis in Human Breast Cancer Cells by Stimulating Oxidative Stress and Inhibiting the Notch-Akt Signaling Pathway ENSG00000134057 ENSG00000198793 ENSG00000168610 PMC8567988__F6 Flavonoid Library Screening Reveals Kaempferol as a Potential Antiviral Agent Against African Swine Fever Virus ENSG00000177169 ENSG00000126775 ENSG00000155792 ENSG00000145782 PMC9597993__F6 Immune checkpoint of B7-H3 in cancer: from immunology to clinical immunotherapy ENSG00000105329 ENSG00000198793 PMC6342515__F1 Therapeutic potential of NAD-boosting molecules: the in vivo evidence ENSG00000105835 ENSG00000180773 ENSG00000086991 ENSG00000278488 ENSG00000172005 ENSG00000157064 ENSG00000262217 ENSG00000103257 ENSG00000173614 ENSG00000008130 ENSG00000172940 PMC8933076__F3 Review of Bile Acid Metabolism and Signaling in Cognitive Dysfunction-Related Diseases ENSG00000108691 ENSG00000036530 PMC5755497__F10A Expression Profiling of Differentiating Emerin-Null Myogenic Progenitor Identifies Molecular Pathways Implicated in Their Impaired Differentiation ENSG00000149311 ENSG00000175054 ENSG00000087586 ENSG00000177519 ENSG00000166851 ENSG00000149554 ENSG00000153827 ENSG00000183765 ENSG00000198625 PMC7725656__F2 Diverse ubiquitin codes in the regulation of inflammatory signaling ENSG00000137275 ENSG00000102871 ENSG00000173039 ENSG00000083799 ENSG00000154124 ENSG00000127191 PMC12128541__F8 Proposed mechanistic pathway for HDAC3 in mediating psoriasis ENSG00000164430 ENSG00000171720 PMC3518543__F4 NFKB activation pathway is regulated by S-nitrosylation ENSG00000291971 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC4789422__F6 Module network of the core network biomarkers in to investigate the bladder carcinogenic mechanisms from stage 1 to stage 4 bladder cancer cells ENSG00000182481 ENSG00000165417 ENSG00000130706 ENSG00000008988 ENSG00000150991 ENSG00000114346 ENSG00000204463 ENSG00000177606 ENSG00000188612 ENSG00000113194 ENSG00000090520 ENSG00000175575 PMC12087080__F2 miR-155 participates in multiple cellular functions ENSG00000134086 ENSG00000168610 PMC4789422__F7 Carcinogenic mechanisms from normal to stage 1 bladder cancer cells (a), and from stage 1 to stage 4 bladder cancer cells (b) ENSG00000135924 ENSG00000008988 ENSG00000150991 ENSG00000114346 ENSG00000175166 ENSG00000188612 ENSG00000113194 PMC12087080__F3 Mechanistic overview of miR-155 in regulating insulin signaling and glucose metabolism ENSG00000136869 PMC5133817__F1 Argon’s molecular mechanism ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC3140053__F1 Genetic Polymorphisms in Inflammation Pathway Genes and Prostate Cancer Risk ENSG00000107562 ENSG00000168610 ENSG00000121966 PMC8033157__F3 Immune evasion by coronaviruses ENSG00000213928 ENSG00000187608 ENSG00000276561 ENSG00000183735 ENSG00000186575 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000130234 ENSG00000136869 ENSG00000131323 ENSG00000135828 ENSG00000175104 PMC9655478__F10 L-Citrulline Supplementation Restrains Ferritinophagy-Mediated Ferroptosis to Alleviate Iron Overload-Induced Thymus Oxidative Damage and Immune Dysfunction ENSG00000167468 ENSG00000125538 PMC8033157__F1 Induction of type I IFNs in response to viral infections ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000203485 ENSG00000164430 ENSG00000088888 ENSG00000134070 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000135828 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC9596766__F1 Two faces of DNA oxidation in genomic and functional mosaicism during aging in human neurons ENSG00000138336 ENSG00000132781 PMC3616892__F6 MTOR in CD4+ T cell differentiation ENSG00000138378 ENSG00000171150 ENSG00000107485 ENSG00000049768 ENSG00000168610 PMC3535427__F1 Targeting 5-lipoxygenase (5-LOX) and cyclooxygenase-2 (COX-2) for colorectal cancer prevention and treatment ENSG00000226275 PMC10873211__F9 Nasal Administration of bFGF-Loaded Nanoliposomes Attenuates Neuronal Injury and Cognitive Deficits in Mice with Vascular Dementia Induced by Repeated Cerebral Ischemia‒Reperfusion ENSG00000181019 ENSG00000079999 PMC7408653__F1 Wnt Signaling Pathway Activation and Inhibition ENSG00000134982 ENSG00000168036 PMC9359433__F1 RET signaling pathway and RET inhibitors in human cancer ENSG00000291971 ENSG00000169047 ENSG00000168610 ENSG00000146094 ENSG00000125170 ENSG00000106070 ENSG00000168546 ENSG00000146013 ENSG00000101134 ENSG00000125861 ENSG00000171119 ENSG00000117407 ENSG00000292254 ENSG00000125650 PMC9359433__F2 RET signaling pathway and RET inhibitors in human cancer ENSG00000168610 PMC9265429__F3 Interaction of mTOR and Nrf2 in Neurogenesis and Its Implication in Neurodegenerative Diseases ENSG00000155792 ENSG00000167965 ENSG00000079999 PMC7532973__F8 Schematic presentation of the mechanisms triggered by HAS3-induced EVs in target cells ENSG00000138798 ENSG00000026508 ENSG00000139549 ENSG00000163501 PMC3191937__F3 Local regulatory proteins that mediate some of the actions of TGFB in human myometrium and leiomyoma ENSG00000159216 PMC3169542__F7 Disruption of TLR3 Signaling Due to Cleavage of TRIF by the Hepatitis A Virus Protease-Polymerase Processing Intermediate, 3CD ENSG00000088888 ENSG00000164342 PMC3466241__F7 Implementation of a High-Throughput Screen for Identifying Small Molecules to Activate the Keap1-Nrf2-ARE Pathway ENSG00000178573 ENSG00000079999 PMC11915071__F3 Biological roles and molecular mechanism of circular RNAs in epithelial-mesenchymal transition of gastrointestinal malignancies ENSG00000134982 ENSG00000105697 ENSG00000168036 ENSG00000083720 ENSG00000137845 ENSG00000168610 ENSG00000147459 PMC4816192__F1 Targeting of BCR and PI3K/AKT signaling as therapeutic strategy in CLL ENSG00000095585 ENSG00000186716 ENSG00000198793 ENSG00000185483 ENSG00000197943 ENSG00000140443 PMC6287618__F1 Role of EGF Receptor Signaling on Morphogenesis of Eyelid and Meibomian Glands ENSG00000070193 ENSG00000163235 ENSG00000113070 ENSG00000095015 ENSG00000146648 ENSG00000065802 PMC8472426__F6 HSPB1 Is Essential for Inducing Resistance to Proteotoxic Stress in Beta-Cells ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC6862663__F1 Gut dysbiosis/permeability increase circulating LPS and exosomal HMGB1, leading to TLR activation in microglia and the induction of iNOS and superoxide ENSG00000189403 ENSG00000106546 PMC8047311__F2 Pathogenesis of AAV and the inhibition of the binding of biological agents ENSG00000005381 ENSG00000101290 PMC9206211__F2 Classic Signaling Pathways in Alveolar Injury and Repair Involved in Sepsis-Induced ALI/ARDS: New Research Progress and Prospect ENSG00000178860 ENSG00000105550 ENSG00000198793 ENSG00000118520 ENSG00000096717 ENSG00000168610 PMC2741134__F2 Inteferons pen the JAK-STAT pathway ENSG00000159128 ENSG00000105397 ENSG00000027697 ENSG00000142166 PMC8593085__F6 An In-Depth Review of Niraparib in Ovarian Cancer: Mechanism of Action, Clinical Efficacy and Future Directions ENSG00000183735 ENSG00000164430 ENSG00000173638 ENSG00000134982 PMC4833639__F1 Many oncogenic mutations drive nutrient transporter gene expression ENSG00000124102 ENSG00000177169 ENSG00000135218 ENSG00000149269 ENSG00000165527 ENSG00000145020 PMC3900493__F1 Lymphotoxin Signaling in Immune Homeostasis and the Control of Microorganisms ENSG00000149564 ENSG00000226275 ENSG00000105656 ENSG00000111321 PMC3900493__F2 Lymphotoxin Signaling in Immune Homeostasis and the Control of Microorganisms ENSG00000226275 ENSG00000111321 PMC3900493__F3 Lymphotoxin Signaling in Immune Homeostasis and the Control of Microorganisms ENSG00000226275 ENSG00000111321 PMC2723867__F1 Dynamics of Membrane Trafficking Downstream of B and T Cell Receptor Engagement: Impact on Immune Synapses ENSG00000177455 ENSG00000095585 ENSG00000291603 ENSG00000070831 ENSG00000134982 ENSG00000010810 ENSG00000186716 ENSG00000173599 ENSG00000197943 PMC11853266__F4 Advanced glycation end products (AGEs) induced inflammatory cell signaling pathways ENSG00000070831 ENSG00000150455 PMC11853266__F5 TLR4 signaling pathway in DPN ENSG00000148400 ENSG00000172936 ENSG00000136869 ENSG00000083799 ENSG00000114315 PMC7072649__F1 Pre-B cell leukemia (PBX3) is a target and a regulator of multiple signaling pathways ENSG00000122025 ENSG00000071575 ENSG00000134982 ENSG00000136997 ENSG00000100985 PMC7867516__F7 Related mechanism responsible for isoflurane-induced proliferation of squamous cervical cancer cells ENSG00000094631 ENSG00000132646 ENSG00000198793 PMC5553593__F7 Interaction network of lysine-succinylated proteins in D ENSG00000166278 PMC6299239__F2 Tankyrase-mediated Wnt/Beta-catenin signalling ENSG00000118518 ENSG00000134982 ENSG00000168036 PMC12122448__F2 Biological processes and genes involved in the Apelin Adipocyte Signaling Pathway, significantly activated by the DOP diet ENSG00000088256 ENSG00000079435 ENSG00000171388 PMC9360879__F5 IL-13 alleviates idiopathic pulmonary hypertension by inhibiting the proliferation of pulmonary artery smooth muscle cells and regulating macrophage infiltration ENSG00000153487 ENSG00000134042 ENSG00000172005 PMC10968029__F1 Illustration of GRB2 in humans and other organisms, highlighting its role in signal transduction and depicting the subcellular localization of GRB2 ENSG00000110395 ENSG00000122257 ENSG00000051180 PMC6348509__F1 Targeting LCSCs by suppression of autophagy and Nanog.Autophagy positively regulated LCSCs by suppressing p53 and favoring the activity of Nanog ENSG00000019991 ENSG00000122691 ENSG00000272398 ENSG00000087586 ENSG00000136869 ENSG00000133961 ENSG00000118777 ENSG00000168610 PMC10610230__F7 Mechanism underlying the therapeutic effect of PT on IDD ENSG00000139219 ENSG00000157766 ENSG00000177606 ENSG00000073756 PMC10968029__F3 Diagrammatic portrayal of GRB2 splicing variants, particularly GRB3-3, in signal transduction ENSG00000196839 ENSG00000092199 PMC10968029__F4 Configuration of GRB2 in Protein Interaction and Signal Transduction ENSG00000033327 ENSG00000110395 ENSG00000156858 ENSG00000291971 ENSG00000169047 ENSG00000198793 ENSG00000146648 PMC8357504__F3 Genome-Wide Expression Difference of MicroRNAs in Basal Cell Carcinoma ENSG00000106571 ENSG00000134574 ENSG00000168036 ENSG00000161202 ENSG00000128602 ENSG00000122008 PMC12003390__F1 Crosstalk between benign non-immune cells and cancer cells ENSG00000107562 ENSG00000291971 ENSG00000173599 ENSG00000169429 ENSG00000128342 ENSG00000168610 ENSG00000121966 PMC5860944__F2 Epidermal growth factor receptor (EGFR) and EGFRvIII in glioblastoma (GBM) ENSG00000132646 ENSG00000128342 ENSG00000146648 ENSG00000196712 PMC2946881__F1 Regulation of adipogenesis by canonical Wnt signaling cascade ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8842579__F3 Battle between host and SARS-CoV-2: Innate immunity and viral evasion strategies ENSG00000213928 ENSG00000187796 ENSG00000185436 ENSG00000169710 ENSG00000142166 ENSG00000183735 ENSG00000088888 ENSG00000136869 ENSG00000164342 ENSG00000124256 ENSG00000120690 ENSG00000196141 ENSG00000278032 ENSG00000116675 ENSG00000185745 ENSG00000185885 ENSG00000138135 ENSG00000105397 ENSG00000115415 ENSG00000142089 ENSG00000243646 ENSG00000131323 ENSG00000158470 ENSG00000135828 ENSG00000175104 PMC8842579__F4 Battle between host and SARS-CoV-2: Innate immunity and viral evasion strategies ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000142166 PMC9346148__F1 腺苷/A2AR信号通路阻断在肿瘤治疗中的应用 ENSG00000156110 ENSG00000196839 PMC6558049__F9 Possible mechanism of CAPE-pNO2 inhibits TNBC growth and metastasis ENSG00000138798 ENSG00000170558 ENSG00000112715 ENSG00000168610 ENSG00000146648 PMC3999750__F4 PAR1 and PAR2 modulate TLR3-dependent expression of IFNB in CFs ENSG00000164342 PMC11754051__F7 Interferon alpha production by the MAGUK-family protein CASK under H5N1 infection ENSG00000115484 ENSG00000283781 ENSG00000147044 ENSG00000276833 ENSG00000276561 PMC8790852__F1 Molecular mechanism(s) of regulation(s) of c-MET/HGF signaling in head and neck cancer ENSG00000019991 ENSG00000291971 ENSG00000198793 ENSG00000026508 ENSG00000168036 ENSG00000124181 ENSG00000168610 ENSG00000146648 PMC7025585__F1 Bat cells mount an antiviral response to RNA viruses, but limit the expression of inflammatory cytokines ENSG00000162711 ENSG00000088888 ENSG00000107201 PMC10564428__F8 Myeloid-specific knockout of SHP2 regulates PI3K/PLCG signaling pathway to protect against early myocardial infarction injury ENSG00000153208 ENSG00000111537 ENSG00000172936 PMC4177028__F2 Intracellular energetic units (ICEUs) ENSG00000135218 ENSG00000004455 ENSG00000172005 PMC11721226__F2 TGFB/SMAD4 signaling pathway in immune cell; A The TGFB/SMAD4 signaling pathway promote the differentiation of naive CD4+ T cells into Th17 cells and regulatory T cells (Tregs) PMC7025585__F2 Exogenous and self-DNA sensing pathways are dampened in bat cells ENSG00000162711 ENSG00000239732 ENSG00000163568 ENSG00000107201 PMC7330108__F2 Cancer cell death induced by Apoptin ENSG00000134982 ENSG00000198793 ENSG00000123374 ENSG00000120868 ENSG00000171791 ENSG00000100985 PMC3134994__F1 Schematic Illustration: TGF-beta signaling pathway PMC4542378__F1 Signaling networks activated during primary KSHV infection as analyzed by Kinex antibody array and IPA ENSG00000171105 ENSG00000172216 ENSG00000102871 ENSG00000291971 ENSG00000169047 ENSG00000127191 ENSG00000146648 PMC3043627__F1 Simplified model for the intersection of signaling pathways regulating protein synthesis and degradation ENSG00000198793 PMC2891946__F7 Crosstalks between EPCR, PAR-1, S1P1, and Tie2 ENSG00000173599 PMC6985208__F2 Signaling pathways associated with highly differentiated proteins in X spermatozoa ENSG00000010256 ENSG00000076555 PMC8091149__F6 Coronavirus Network Explorer: mining a large-scale knowledge graph for effects of SARS-CoV-2 on host cell function ENSG00000100234 ENSG00000115008 ENSG00000137275 ENSG00000139269 ENSG00000173039 ENSG00000065559 ENSG00000130159 ENSG00000177663 ENSG00000168610 ENSG00000124391 ENSG00000104368 ENSG00000288411 ENSG00000112116 ENSG00000073060 ENSG00000177606 ENSG00000006451 ENSG00000135919 PMC6985208__F3 Signaling pathways associated with highly differentiated proteins in Y spermatozoa ENSG00000183785 ENSG00000110435 ENSG00000171595 PMC7279580__F6 Zika virus dysregulates human Sertoli cell proteins involved in spermatogenesis with little effect on tight junctions ENSG00000138798 ENSG00000154059 PMC1234333__F7 Knockdown of Smad4 affects only a subset of TGF-Beta-regulated target genes and functions ENSG00000111145 ENSG00000159216 ENSG00000198742 ENSG00000019549 ENSG00000124766 ENSG00000115221 ENSG00000099860 ENSG00000107485 ENSG00000114315 PMC5322275__F3 Schematic model summarizing the findings of the proteomic and metabonomic profiling analyses ENSG00000100084 ENSG00000184470 ENSG00000148660 ENSG00000164061 ENSG00000150672 ENSG00000125675 ENSG00000198793 ENSG00000163914 ENSG00000220205 ENSG00000120251 ENSG00000132535 ENSG00000128191 PMC10551897__F11 KEGG pathway diagram for PI3K-AKT signalling pathway ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000169047 PMC4727329__F7 MILP model identifies causal relationships from PI3K/AKT and TP53 pathways (KEGG) (a) PI3K/AKT pathway is altered in phase 1 of breast cancer progression; (b) TP53 pathway is altered in phase 2 of breast cancer progression ENSG00000198793 ENSG00000121879 PMC10551897__F12 KEGG pathway diagram for EGFR tyrosine kinase inhibitor resistance pathway ENSG00000169291 ENSG00000157764 ENSG00000146648 PMC10551897__F13 KEGG pathway diagram for MAPK signalling pathway ENSG00000170458 ENSG00000102871 ENSG00000130159 ENSG00000175104 ENSG00000127191 ENSG00000026103 PMC4982440__F6 Proposed Model of PI3KA Resistance in SGK1-Expressing CellsPIK3CA-mutant breast tumors depend on the PI3K pathway, which mainly signals through AKT ENSG00000118515 PMC4108926__F2 Melanoma and integrated Breast cancer pathway landscape ENSG00000149311 ENSG00000065833 ENSG00000026103 PMC2724002__F2 Controlling Hair Follicle Signaling Pathways through Polyubiquitination ENSG00000106571 ENSG00000164690 PMC2766659__F4 Signaling molecules and pathways regulating the fate of spermatogonial stem cells ENSG00000291971 PMC11506536__F2 Illustrates the multifaceted mechanisms of action of niclosamide in cancer treatment ENSG00000134982 ENSG00000198793 ENSG00000164327 ENSG00000171540 ENSG00000168610 PMC9367165__F2 Twinkle twinkle brittle star: the draft genome of Ophioderma brevispinum (Echinodermata: Ophiuroidea) as a resource for regeneration research ENSG00000140564 ENSG00000069869 ENSG00000182827 ENSG00000139517 ENSG00000101346 ENSG00000188095 ENSG00000133961 PMC8086092__F12 Comparative transcriptomic analysis reveals the regulatory mechanism of the gibberellic acid pathway of Tartary buckwheat (Fagopyrum tataricum (L.) Gaertn.) dwarf mutants ENSG00000069482 ENSG00000113558 PMC9212771__F6 In silico drug repurposing against SARS-CoV-2 using an integrative transcriptomic profiling approach: Hydrocortisone and Benzhydrocodone as potential drug candidates against COVID-19 ENSG00000002330 ENSG00000185591 ENSG00000152193 ENSG00000128342 PMC6702832__F5 Modulation of the NFE2L2 pathway in keratinocytes ENSG00000116044 ENSG00000175793 ENSG00000178573 ENSG00000106546 PMC6263799__F1 Summary of the current model of the GET pathway ENSG00000198356 ENSG00000182093 ENSG00000239857 PMC6702832__F6 Modulation of the NFE2L2 pathway in melanocytes ENSG00000116044 ENSG00000178573 ENSG00000079999 PMC6702832__F7 The NFE2L2 pathway in fibroblasts ENSG00000116044 ENSG00000175793 ENSG00000178573 PMC2928959__F6 Hypothetical model for EGFR-dependent loss of cell polarity and activation of Wnt signaling in CS-exposed human airway epithelium ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000146648 PMC5537818__F6 Underlying mechanisms of n-3 PUFAs protecting metabolic syndrome ENSG00000042832 ENSG00000172936 ENSG00000026103 PMC12040899__F10 SUMOylation and SAFB2 in PDAC Progression ENSG00000168036 ENSG00000185567 ENSG00000130254 PMC4871587__F3 Comparison between Timelines of Transcriptional Regulation in Mammals, Birds, and Teleost Fish Somitogenesis ENSG00000163512 ENSG00000170961 ENSG00000167325 ENSG00000136997 ENSG00000197943 ENSG00000106003 ENSG00000183520 PMC7082839__F7 Diverse APJ signaling pathways activated by prolonged mechanical load or apelin ENSG00000198793 ENSG00000198626 PMC3690588__F1 Wnt signaling ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC2790152__F3 A model of the inhibitor of growth (ING) 2 signaling pathway ENSG00000096717 ENSG00000114115 PMC7082839__F4 AT1R signaling pathways activated by prolonged mechanical load or Ang II ENSG00000175054 ENSG00000198793 ENSG00000137672 ENSG00000138741 ENSG00000146648 PMC2671642__F5 Comprehensive genomic characterization defines human glioblastoma genes and core pathways ENSG00000135446 ENSG00000134853 ENSG00000105810 ENSG00000118971 ENSG00000146648 ENSG00000139687 ENSG00000196712 ENSG00000198625 PMC4881178__F7 Proposed pathway of ASPE signaling in MDA-MB-231 cells ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC5855681__F2 MicroRNAs regulate gene transcription ENSG00000100811 ENSG00000092847 ENSG00000178691 ENSG00000128191 ENSG00000113360 PMC3294426__F3A Into the Eye of the Cytokine Storm ENSG00000274211 ENSG00000134339 ENSG00000120833 ENSG00000185634 ENSG00000114113 ENSG00000282905 ENSG00000228278 ENSG00000048462 ENSG00000102871 ENSG00000162267 ENSG00000095015 ENSG00000115904 ENSG00000197442 ENSG00000169032 ENSG00000135341 ENSG00000100485 ENSG00000229314 ENSG00000182326 ENSG00000196628 ENSG00000179295 ENSG00000172216 ENSG00000148082 ENSG00000129946 ENSG00000154310 ENSG00000158874 ENSG00000180008 ENSG00000171560 ENSG00000115008 ENSG00000113600 ENSG00000137275 ENSG00000151655 ENSG00000130159 ENSG00000168610 ENSG00000113905 ENSG00000145192 ENSG00000177606 ENSG00000172936 ENSG00000184216 ENSG00000127863 ENSG00000114115 PMC4081675__F1 Signaling pathways regulating hepatic stellate cell activation in alcoholic liver disease ENSG00000136869 ENSG00000171791 PMC1447421__F10 Hypothetical model describing the roles of Rad18 and PolK in the BPDE-induced S-phase checkpoint ENSG00000149311 ENSG00000175054 ENSG00000132646 ENSG00000070950 ENSG00000122008 PMC7379175__F8 Model depicting the relationship between CIBZ, RB1CC1 and autophagy ENSG00000177169 ENSG00000123395 ENSG00000023287 PMC7477886__F3 Simulated network from genetic variant to disease constructed from the insulin signaling pathway from KEGG ENSG00000171105 ENSG00000002330 ENSG00000005882 ENSG00000150907 ENSG00000198793 ENSG00000026103 PMC7477886__F4 Whole network from APOE genotype to AD constructed from KEGG-based Alzheimer’s disease pathway ENSG00000132906 ENSG00000002330 ENSG00000149782 ENSG00000133318 ENSG00000123104 ENSG00000168040 ENSG00000137845 ENSG00000064012 ENSG00000164305 PMC2904682__F1 Schematic model of regulatory pathways involved in Mycn stabilization ENSG00000127445 ENSG00000005882 ENSG00000198793 ENSG00000164327 ENSG00000105723 ENSG00000140443 PMC7407487__F4 Calcium-Sensing Receptor and Regulation of WNK Kinases in the Kidney ENSG00000126562 ENSG00000080166 ENSG00000036828 PMC11706183__F8 Uncovering iron imbalance and inositol metabolism disruption: insights from the yeast model of N88S seipinopathy ENSG00000127445 ENSG00000173599 PMC2883240__F1 Signaling pathways involving molecular markers for human breast cancer ENSG00000228716 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000121068 ENSG00000135446 ENSG00000132646 ENSG00000177606 ENSG00000152592 ENSG00000135111 ENSG00000139618 PMC2453756__F1 Pathway of murine Th17 differentiation ENSG00000166090 ENSG00000049768 PMC7569249__F5 Overexpression of Rab40b promotes hepatocellular carcinoma cell proliferation and metastasis by upregulating cyclin D1, cyclin E1 and MMP2 via PI3K/AKT signaling pathway ENSG00000087245 ENSG00000141542 PMC2897739__F1 Recent advances in the genetics of systemic lupus erythematosus ENSG00000169896 ENSG00000140968 ENSG00000116701 ENSG00000143226 ENSG00000185651 ENSG00000276561 ENSG00000057663 ENSG00000142166 ENSG00000239732 ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000118503 ENSG00000175104 PMC2752361__F3 MOLECULAR CONSTITUTION OF BREAST BUT NOT OTHER REPRODUCTIVE TISSUES IS RICH IN GROWTH PROMOTING MOLECULES ENSG00000125740 ENSG00000112964 ENSG00000134215 ENSG00000177606 ENSG00000102678 ENSG00000104723 PMC5557856__F6 Proposed mechanism by which CoQ10H2 improves metabolic function and inhibits insulin resistance in KKAy mice ENSG00000096717 ENSG00000026103 PMC7140893__F6 Gene–gene interaction (GGI) and protein–protein interaction (PPI) predicted networks of DEGs enriched in the extracellular exosome post heat stress ENSG00000113889 ENSG00000198053 ENSG00000196154 ENSG00000055955 ENSG00000242616 ENSG00000135905 ENSG00000106927 ENSG00000163631 ENSG00000133313 ENSG00000120063 ENSG00000197956 ENSG00000120742 ENSG00000121410 ENSG00000133110 ENSG00000213658 ENSG00000118785 ENSG00000170458 ENSG00000145192 ENSG00000196352 ENSG00000158874 ENSG00000127824 ENSG00000171560 ENSG00000154096 PMC8939180__F4 Metabolome and transcriptome analyses identify the plant immunity systems that facilitate sesquiterpene and lignan biosynthesis in Syringa pinnatifolia Hemsl. ENSG00000110921 ENSG00000197429 ENSG00000167508 ENSG00000084774 PMC6523117__F7 Suggested mechanism of rFlaA:Betv1-mediated mDC activation ENSG00000187554 ENSG00000198793 ENSG00000172936 ENSG00000175104 ENSG00000168610 ENSG00000184216 PMC9688731__F3 Extracellular Vesicles in Multiple Myeloma—Cracking the Code to a Better Understanding of the Disease ENSG00000178860 ENSG00000109321 ENSG00000100985 ENSG00000146648 ENSG00000121966 PMC6563125__F8 Model of interaction between an oncolytic virus and the host type I IFN response and cyclin expression ENSG00000213928 ENSG00000089127 ENSG00000115415 ENSG00000123374 PMC7825104__F3 Adrenergic signalling pathway and mechanisms ENSG00000002330 ENSG00000157764 ENSG00000198793 ENSG00000019549 ENSG00000168610 ENSG00000131023 PMC2713319__F1 Apoptosis and Epithelial Injury in the Lungs ENSG00000168040 ENSG00000026103 PMC1522081__F7 Involvement of MACF1 in the Wnt/Beta-catenin signaling pathway ENSG00000134982 PMC2713319__F3 Apoptosis and Epithelial Injury in the Lungs ENSG00000170458 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000168040 ENSG00000026103 PMC7217787__F1 Rapamycin use in COVID-19 ENSG00000088888 ENSG00000130234 ENSG00000198793 ENSG00000026508 PMC8053758__F4 Promising targets for therapy of osteoarthritis: a review on the Wnt and TGFB signalling pathways ENSG00000150907 ENSG00000096717 PMC3753498__F9 Schematic representation of methionine metabolism via methionine cycle and transsulfuration pathway showing cysteine as a precursor of GSH and hydrogen sulfide (H2S) PMC5850680__F1 Under the action of BMP2 and inflammatory mediators such as tumor necrosis factor, the expression of transcription factors Runx2 and osterix can be activated via the BMP/Smad pathway ENSG00000281324 ENSG00000130881 ENSG00000120149 ENSG00000132693 PMC5913738__F2 Intermittent metabolic switching, neuroplasticity and brain health ENSG00000177169 ENSG00000198793 ENSG00000142082 ENSG00000106459 PMC5913738__F3 Intermittent metabolic switching, neuroplasticity and brain health ENSG00000198793 ENSG00000096717 ENSG00000142082 PMC11534336__F1 Schematic models of the core of MAPK/ERK pathway and human eIF3 complex ENSG00000163435 ENSG00000149269 ENSG00000284161 PMC2634257__F1 Simplified schemes of the three Wnt signaling cascades ENSG00000138795 ENSG00000100592 ENSG00000163914 ENSG00000168036 PMC3111485__F5 A Large Gene Network in Immature Erythroid Cells Is Controlled by the Myeloid and B Cell Transcriptional Regulator PU.1 ENSG00000033327 PMC5306369__F1 Complement activation and evasion by NS1 protein of flavivirus ENSG00000039537 ENSG00000113600 ENSG00000244731 ENSG00000182326 ENSG00000236625 PMC10198710__F2 m6A methylases that participate in cancer glycolytic metabolic pathways ENSG00000145388 ENSG00000149658 ENSG00000171634 ENSG00000091542 ENSG00000146457 ENSG00000165819 ENSG00000159399 PMC5774705__F3 Hybrid genome assembly and annotation of Paenibacillus pasadenensis strain R16 reveals insights on endophytic life style and antifungal activity ENSG00000142599 PMC9563266__F2 MARCKS in Metastasis and Treatment Resistance of Solid Tumors ENSG00000100985 PMC3315682__F1 Serine biosynthetic pathway ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC4282831__F3 Seeing through VEGF: Innate and adaptive immunity in pathologic angiogenesis in the eye ENSG00000125538 ENSG00000196352 ENSG00000075213 PMC10198710__F3 m6A methylases that participate in ferroptosis ENSG00000145388 ENSG00000151012 ENSG00000198492 ENSG00000072274 ENSG00000091542 ENSG00000168003 ENSG00000156299 ENSG00000149658 ENSG00000167468 ENSG00000047188 ENSG00000073792 ENSG00000111371 ENSG00000165819 PMC4339613__F3 Dual roles of NRF2 in tumor prevention and progression: possible implications in cancer treatment ENSG00000134086 ENSG00000178573 ENSG00000079999 PMC1866211__F1 Hedgehog signalling pathway ENSG00000143839 ENSG00000121067 PMC6092617__F7 Targeting prohibitins at the cell surface prevents Th17‐mediated autoimmunity ENSG00000215021 ENSG00000049768 ENSG00000112115 PMC5727329__F2 DKK1 regulation of signalling pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000136026 PMC5823660__F3 An integrative transcriptomic approach to identify depot differences in genes and microRNAs in adipose tissues from high fat fed mice ENSG00000128272 ENSG00000127022 ENSG00000100219 ENSG00000171791 ENSG00000127191 PMC8838622__F1 An Emerging Role of Defective Copper Metabolism in Heart Disease ENSG00000123191 ENSG00000177556 PMC8472298__F2 Insulin and Insulin Resistance in Alzheimer’s Disease ENSG00000169047 ENSG00000198793 PMC10907440__F2 Positive effects of SGK1 in embryogenesis ENSG00000118515 ENSG00000112715 PMC2865489__F1 The estradiol-synthetic pathway and nuclear receptors PMC2788159__F1 Regulation of mTORC1 mTORC1 is a multiprotein complex composed of Raptor, mLST8, PRAS40, and FKBP38 and regulates protein synthesis and cell growth by phosphorylating S6K1 and 4EBP1 ENSG00000198793 PMC8403639__F1 NRF2 signaling pathway ENSG00000181019 ENSG00000178573 ENSG00000023909 ENSG00000079999 PMC2788159__F2 Current proposed mechanisms of amino acid sensing by mTORC1 Amino acids are imported into the cells via various amino acid transporters and activate mTORC1 either by amino acid metabolites or by undefined membrane/intracellular amino acid sensor(s) PMC4303015__F2 microRNA-21 Mediates Stretch-Induced Osteogenic Differentiation in Human Periodontal Ligament Stem Cells ENSG00000049323 ENSG00000039319 ENSG00000123612 ENSG00000139567 ENSG00000183682 ENSG00000164093 ENSG00000042088 ENSG00000204217 ENSG00000114739 ENSG00000137801 PMC6506819__F3 Disease-Associated Genetic Variation in Human Mitochondrial Protein Import ENSG00000162600 ENSG00000136758 PMC11781172__F1 Novel representative therapeutic targets for SCLC ENSG00000089692 ENSG00000181847 ENSG00000087586 ENSG00000090932 PMC7851145__F1 LPA intra- and extracellular biosynthesis and degradation ENSG00000129219 ENSG00000173599 ENSG00000198670 PMC9578258__F2 Synthetic lethality of targeting cell cycle checkpoints and PARPs in cancer treatment ENSG00000143799 ENSG00000083093 ENSG00000101224 ENSG00000139618 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000134574 ENSG00000167986 ENSG00000123374 ENSG00000051180 ENSG00000138375 ENSG00000143971 ENSG00000136936 ENSG00000138385 PMC5294251__F7 Proposed model for the CD271 regulation and potential downstream effects mediating drug resistance and metastasis ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000117650 ENSG00000131747 ENSG00000253729 ENSG00000111247 PMC8270677__F4 Replication Stress Response on a Narrow Path Between Genomic Instability and Inflammation ENSG00000051180 PMC5381059__F1 Cancer immunotherapies targeting the PD-1 signaling pathway ENSG00000134982 PMC7125293__F4 Transcriptome analysis on fructose as the sole carbon source enhancing perylenequinones production of endophytic fungus Shiraia sp. Slf14 ENSG00000100473 ENSG00000196839 PMC8422427__F6 Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications ENSG00000128272 ENSG00000144895 ENSG00000125538 ENSG00000100219 ENSG00000127191 PMC10902513__F2 TGFB/Smad signaling pathway involved in radiation skin fibrosis PMC8578301__F1 Clinical and biochemical footprints of inherited metabolic diseases. VI. Metabolic dermatoses. ENSG00000179148 ENSG00000179477 ENSG00000170426 ENSG00000118402 ENSG00000171954 ENSG00000119915 ENSG00000167114 ENSG00000135069 ENSG00000146733 ENSG00000154227 ENSG00000100596 ENSG00000092621 ENSG00000066322 ENSG00000119537 ENSG00000148154 ENSG00000172296 PMC8648894__F1 Signaling in the crowded cell ENSG00000101407 ENSG00000164879 ENSG00000177058 ENSG00000108960 ENSG00000198793 ENSG00000155792 ENSG00000146648 PMC5652738__F9 Targeting the HGF/c-MET pathway: stromal remodelling in pancreatic cancer ENSG00000019991 ENSG00000168610 ENSG00000146648 PMC7403652__F4 KEGG pathway with significantly enriched differentially expressed proteins ENSG00000184990 ENSG00000149311 ENSG00000065833 ENSG00000002330 ENSG00000082175 ENSG00000042286 ENSG00000123374 ENSG00000112378 ENSG00000026103 PMC4600925__F4 SGK1-mediated signaling pathway ENSG00000005882 ENSG00000060237 ENSG00000118515 PMC3289952__F1 Selected essential fatty acids molecular mechanisms ENSG00000154258 ENSG00000160179 PMC9387202__F10 The gut microbiota and lipidomic profiles by black chokeberry (Aronia melanocarpa L.) polyphenols via the glycerophospholipid metabolism signaling pathway ENSG00000129219 ENSG00000087253 ENSG00000173599 PMC10561294__F7 Construction of PPI networks ENSG00000081041 ENSG00000140379 ENSG00000149968 ENSG00000163734 ENSG00000108342 ENSG00000115009 PMC3289952__F2 Proposed role of essential fatty acids in “micromanaging” molecular actions ENSG00000172216 ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC6437734__F6 VPA induces apoptosis in neutrophils and diminishes their phagocytic capacity ENSG00000171049 PMC6437734__F8 VPA affects IL-12-, IL-15-, and IL-18-mediated IFNG production in NK cells ENSG00000138378 ENSG00000111537 ENSG00000172936 ENSG00000105639 PMC6008067__F5 Proximity of Bcl-xl to p38, MK2, and RTN4 in platelet function ENSG00000142192 ENSG00000162704 ENSG00000177733 ENSG00000115310 ENSG00000083312 ENSG00000274205 ENSG00000168610 ENSG00000106683 ENSG00000117020 ENSG00000115415 ENSG00000291814 ENSG00000173757 ENSG00000010810 ENSG00000112208 ENSG00000123908 ENSG00000127948 PMC1592643__F3 An altered balance of proapoptotic and antiapoptotic molecules in trauma patients' T cells could indicate specifically increased vulnerability to apoptotic depletion ENSG00000139193 ENSG00000002330 ENSG00000067900 ENSG00000120868 ENSG00000148935 ENSG00000215788 ENSG00000084774 ENSG00000115317 ENSG00000185104 ENSG00000026103 PMC7232489__F2 Bifurcated pathway to synthesize hexanoic acid in M ENSG00000120437 PMC6172370__F8 P38 MAPK signaling pathway in the regulation of the NLRP3 inflammasome and macrophage pyroptosis ENSG00000162711 ENSG00000125538 PMC4908728__F8 Schematic showing the effects of RBE on LPS-activated microglia ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC6862352__F1 Hh in the ischemic skeletal muscle ENSG00000164690 ENSG00000139549 ENSG00000163501 PMC11077380__F2 Mechanism diagram illustrates the crosstalk between Se-AA metabolism and various cell types in the TME ENSG00000211445 ENSG00000026103 PMC10740873__F2 Ihh signaling pathway in regulating osteoblast differentiation (refer to Pan et al ENSG00000106571 ENSG00000125398 ENSG00000128602 ENSG00000163501 PMC11077380__F3 Antitumor application of Se-AAs ENSG00000131015 ENSG00000171791 ENSG00000231179 ENSG00000204520 ENSG00000138385 PMC3733582__F3 Pathway Linker Results for AChE and BChE ENSG00000114200 ENSG00000113196 ENSG00000142192 ENSG00000206561 ENSG00000087085 ENSG00000101680 PMC3830643__F2 Lipid Synthesis in Protozoan Parasites: a Comparison Between Kinetoplastids and Apicomplexans ENSG00000011007 ENSG00000154582 PMC9284119__F5 Overexpression of TwSQS, TwSE, and TwOSC Regulates Celastrol Accumulation in Cambial Meristematic Cells and Dedifferentiated Cells ENSG00000197429 ENSG00000127948 PMC6010849__F10 Schematic overview of Nrf2 signalling crosstalk to both Wnt3a/B‐catenin and AMPK pathway in COPD/emphysema ENSG00000154342 ENSG00000181019 PMC2652645__F1A Detailed qualitative dynamic knowledge representation using a BioNetGen model of TLR-4 signaling and preconditioning ENSG00000104237 ENSG00000170458 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC11048799__F5 Mechanism by which GAA promotes muscle development and growth through mirNA-targeted gene regulatory signaling pathway [27,43,44,47,48,49,50,51] ENSG00000291507 ENSG00000170962 ENSG00000198793 ENSG00000197461 PMC5983927__F7 Antitumor effects of corilagin ENSG00000168040 ENSG00000026103 PMC7817854__F2 miRNAs targeting SMO oncogenic hedgehog pathway to induce apoptosis in CRC ENSG00000173040 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC7261959__F12 Alterations induced on SIRT1/PGC-1A pathway by ABOs ENSG00000096717 ENSG00000171109 ENSG00000106459 PMC6437734__F1 VPA inhibits LPS signaling in macrophages ENSG00000170458 ENSG00000172936 ENSG00000157625 ENSG00000175104 PMC6741997__F8 Model of the neuronal death pathway involving Cdks ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC6437734__F2 VPA induces M1-M2 polarization of macrophages in response to LPS PMC6437734__F4 VPA inhibits monocyte to DC cell differentiation ENSG00000137265 ENSG00000113520 ENSG00000112149 ENSG00000168610 PMC9106028__F1 Front-Line Therapy for Metastatic Renal Cell Carcinoma: A Perspective on the Current Algorithm and Future Directions ENSG00000167601 ENSG00000134982 ENSG00000163599 ENSG00000198793 PMC9343600__F11 Linagliptin in Combination With Metformin Ameliorates Diabetic Osteoporosis Through Modulating BMP-2 and Sclerostin in the High-Fat Diet Fed C57BL/6 Mice ENSG00000159224 ENSG00000197635 ENSG00000168610 PMC7235440__F1 Herpesvirus host shutoff-associated proteins mediate evasion of the type I IFN signaling pathway (refer to ) ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000163565 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC9641750__F6 Mitigation of Multi-Organ Radiation Injury with ACE2 Agonist Diminazene Aceturate ENSG00000130234 PMC8123313__F1 Leptin Receptor Compound Heterozygosity in Humans and Animal Models ENSG00000150907 ENSG00000115138 ENSG00000168610 PMC8196557__F6 miRNAs and Genes Involved in the Interplay between Ocular Hypertension and Primary Open-Angle Glaucoma. Oxidative Stress, Inflammation, and Apoptosis Networks ENSG00000029363 ENSG00000204104 ENSG00000230930 ENSG00000122420 ENSG00000123240 ENSG00000105327 ENSG00000099968 ENSG00000237412 ENSG00000118096 ENSG00000138829 ENSG00000101280 ENSG00000092200 ENSG00000176101 ENSG00000171791 ENSG00000198598 ENSG00000147526 ENSG00000166147 ENSG00000134987 ENSG00000188153 ENSG00000172037 ENSG00000160202 ENSG00000204262 ENSG00000157500 ENSG00000041982 ENSG00000157227 ENSG00000108821 ENSG00000139687 ENSG00000087245 ENSG00000160145 ENSG00000166278 ENSG00000125347 ENSG00000063660 ENSG00000167468 ENSG00000131323 ENSG00000130508 ENSG00000135218 ENSG00000070831 ENSG00000105329 ENSG00000169031 ENSG00000112715 ENSG00000164305 ENSG00000119681 ENSG00000114738 ENSG00000137801 ENSG00000180210 ENSG00000132530 ENSG00000100473 ENSG00000120868 ENSG00000026103 ENSG00000132906 ENSG00000039537 ENSG00000259207 ENSG00000113140 ENSG00000115221 ENSG00000134871 ENSG00000164171 ENSG00000148935 ENSG00000112977 ENSG00000129038 ENSG00000154485 ENSG00000096872 ENSG00000117601 ENSG00000130714 ENSG00000174099 ENSG00000198576 ENSG00000075891 ENSG00000170653 ENSG00000171812 ENSG00000120471 ENSG00000126778 ENSG00000125124 ENSG00000122970 ENSG00000198625 ENSG00000196116 PMC9293517__F5 Explore the Therapeutic Composition and Mechanism of Schisandra chinensis-Acorus tatarinowii Schott on Alzheimer's Disease by Using an Integrated Approach on Chemical Profile, Network Pharmacology, and UPLC-QTOF/MS-Based Metabolomics Analysis ENSG00000171105 ENSG00000140505 ENSG00000087085 ENSG00000007908 ENSG00000196396 ENSG00000180210 ENSG00000151834 ENSG00000133019 ENSG00000274247 ENSG00000082175 ENSG00000177606 ENSG00000095303 ENSG00000123374 ENSG00000149554 ENSG00000156113 PMC3319358__F2 Gut triglyceride production ENSG00000152700 ENSG00000042832 ENSG00000168282 ENSG00000285482 ENSG00000197299 ENSG00000120437 ENSG00000062282 ENSG00000292366 PMC2668982__F2 CCN1 signaling and crosstalk with TNFA ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000064012 PMC6355473__F4 New targeted therapies in advanced primary cutaneous anaplastic large cell lymphoma ENSG00000148400 ENSG00000004455 ENSG00000168610 PMC7563957__F1 Simplified diagram of the 5-fluorouracil (5FU) conversion system ENSG00000167325 ENSG00000171848 ENSG00000167900 PMC3319358__F1 Gut triglyceride production ENSG00000158669 ENSG00000285482 ENSG00000197299 ENSG00000062282 PMC6848764__F2 Working model for CILK1 signalling ENSG00000109083 ENSG00000106571 ENSG00000155792 ENSG00000167965 ENSG00000128602 PMC6348090__F10 Transcriptome profiling reveals the role of ZBTB38 knock-down in human neuroblastoma ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 PMC6607389__F3 Protein-protein interaction network complex and modular analysis ENSG00000129514 ENSG00000088002 ENSG00000134193 ENSG00000052344 ENSG00000075461 ENSG00000157227 ENSG00000240771 ENSG00000282604 ENSG00000139515 ENSG00000166482 ENSG00000112655 ENSG00000277263 ENSG00000163017 ENSG00000022267 ENSG00000285251 ENSG00000117983 ENSG00000254709 ENSG00000285136 ENSG00000162576 ENSG00000277753 ENSG00000132329 ENSG00000282830 ENSG00000117228 ENSG00000170369 ENSG00000144810 ENSG00000146469 ENSG00000163431 ENSG00000101470 ENSG00000179914 ENSG00000170373 ENSG00000173641 ENSG00000170498 ENSG00000276920 ENSG00000167641 ENSG00000170801 ENSG00000162591 ENSG00000166033 ENSG00000140807 ENSG00000172828 ENSG00000138207 ENSG00000103018 ENSG00000084764 ENSG00000117122 ENSG00000102837 ENSG00000164946 ENSG00000063660 ENSG00000102796 ENSG00000134824 ENSG00000101188 ENSG00000070526 ENSG00000143412 ENSG00000106384 ENSG00000184709 ENSG00000115523 ENSG00000110195 ENSG00000292195 ENSG00000011347 ENSG00000188783 ENSG00000182253 ENSG00000166869 ENSG00000092758 ENSG00000174080 ENSG00000196154 ENSG00000124107 ENSG00000129757 ENSG00000111341 ENSG00000152137 ENSG00000118898 ENSG00000172238 ENSG00000026103 ENSG00000164379 ENSG00000070404 ENSG00000106483 ENSG00000102854 ENSG00000277943 ENSG00000019582 ENSG00000113296 ENSG00000198488 ENSG00000141655 ENSG00000134757 ENSG00000143320 ENSG00000138755 ENSG00000163734 ENSG00000135919 ENSG00000162896 ENSG00000104689 ENSG00000162654 ENSG00000007171 ENSG00000067715 ENSG00000169245 ENSG00000102760 ENSG00000049323 ENSG00000169248 ENSG00000133067 ENSG00000163739 ENSG00000105664 ENSG00000009950 ENSG00000131142 ENSG00000125538 ENSG00000163501 ENSG00000157514 ENSG00000101210 ENSG00000081041 ENSG00000164694 ENSG00000184661 ENSG00000145649 ENSG00000138080 ENSG00000262243 PMC3362922__F1 Hexosamine biosynthetic pathway and its dependent processes ENSG00000147162 ENSG00000168066 ENSG00000102172 ENSG00000013375 PMC3281607__F2 Antioxidant roles of Prx I, Prx III, and Srx in ethanol-fed mouse liver ENSG00000130649 ENSG00000105227 ENSG00000079999 PMC6219086__F5 DE genes on “Wnt Signaling Pathway and Pluripotency” pathway upon S ENSG00000073711 ENSG00000177485 ENSG00000001167 ENSG00000221914 ENSG00000134982 ENSG00000168036 ENSG00000135341 ENSG00000163558 ENSG00000136997 ENSG00000166501 ENSG00000165879 ENSG00000184304 ENSG00000027075 ENSG00000107404 ENSG00000137673 ENSG00000005339 ENSG00000198561 ENSG00000276920 ENSG00000132693 ENSG00000140807 ENSG00000071564 ENSG00000007168 ENSG00000067606 ENSG00000177606 ENSG00000168646 PMC12183286__F2 TREM2 signaling pathway (by Figdraw) ENSG00000070831 ENSG00000291971 ENSG00000134215 ENSG00000115904 ENSG00000168036 ENSG00000043462 ENSG00000137845 ENSG00000100485 ENSG00000141968 ENSG00000213658 ENSG00000146094 ENSG00000173599 ENSG00000198087 ENSG00000136869 ENSG00000172936 ENSG00000160293 ENSG00000086730 PMC6219086__F6 Insulin signaling pathway ENSG00000104812 ENSG00000140992 ENSG00000065675 ENSG00000136111 ENSG00000169047 ENSG00000142273 ENSG00000165527 ENSG00000100485 ENSG00000173327 ENSG00000107263 ENSG00000163558 ENSG00000148082 ENSG00000106070 ENSG00000220205 ENSG00000100219 ENSG00000065559 ENSG00000132356 ENSG00000132639 ENSG00000187840 ENSG00000104814 ENSG00000110395 ENSG00000197879 ENSG00000133124 ENSG00000079435 ENSG00000152556 ENSG00000130758 ENSG00000050748 ENSG00000136854 ENSG00000095015 ENSG00000115904 ENSG00000141639 ENSG00000168067 ENSG00000142733 ENSG00000166484 ENSG00000069956 ENSG00000139625 ENSG00000135341 ENSG00000121879 ENSG00000196396 ENSG00000137764 ENSG00000116266 ENSG00000115290 ENSG00000166592 ENSG00000168118 ENSG00000179295 ENSG00000169967 ENSG00000073803 ENSG00000166263 ENSG00000011566 ENSG00000101049 ENSG00000141503 ENSG00000143761 ENSG00000040933 ENSG00000129946 ENSG00000165458 ENSG00000197594 ENSG00000024422 ENSG00000026103 ENSG00000027075 ENSG00000171105 ENSG00000104365 ENSG00000111713 ENSG00000006062 ENSG00000186298 ENSG00000160691 ENSG00000185386 ENSG00000101255 ENSG00000067606 ENSG00000162409 ENSG00000177606 ENSG00000188130 ENSG00000171608 ENSG00000163754 ENSG00000105723 PMC8165772__F7 Whole-genome resequencing provides insights into the population structure and domestication signatures of ducks in eastern China ENSG00000169291 ENSG00000197594 PMC7028855__F2 miR212 and Hedgehog pathway ENSG00000106571 ENSG00000166813 ENSG00000164690 ENSG00000128602 PMC10537781__F9 African swine fever virus I10L protein inhibits the NFKB signaling pathway by targeting IKKB ENSG00000102871 ENSG00000172936 ENSG00000175104 ENSG00000127191 ENSG00000184216 ENSG00000076604 PMC8687399__F8 Petri Net modelling approach for analysing the behaviour of Wnt/ ‐catenin and Wnt/ Ca2+ signalling pathways in arrhythmogenic right ventricular cardiomyopathy ENSG00000087095 ENSG00000162337 ENSG00000134982 ENSG00000171791 PMC4159616__F1 Bile Acids, Obesity, and the Metabolic Syndrome ENSG00000180432 ENSG00000115271 ENSG00000135929 PMC8070467__F2 Metabolic link between diabetes and cancer ENSG00000138798 ENSG00000198793 PMC8687399__F6 Petri Net modelling approach for analysing the behaviour of Wnt/ ‐catenin and Wnt/ Ca2+ signalling pathways in arrhythmogenic right ventricular cardiomyopathy ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8687399__F7 Petri Net modelling approach for analysing the behaviour of Wnt/ ‐catenin and Wnt/ Ca2+ signalling pathways in arrhythmogenic right ventricular cardiomyopathy ENSG00000132906 ENSG00000291983 ENSG00000120868 ENSG00000171791 ENSG00000127191 ENSG00000164305 PMC8038768__F8 Overview of this study ENSG00000019991 ENSG00000213445 PMC7933006__F2 Reduced Tdo2 expression leads to reduced Trp flux through the kynurenine pathway (KP) ENSG00000262635 ENSG00000129167 ENSG00000241644 ENSG00000103257 PMC6908615__F8 Illustration on the possible underlying pharmacological mechanism of neurotrophic activity of SCH in cultured hippocampal neurons ENSG00000284254 ENSG00000083720 PMC3687624__F1 Simplified view of the canonical Wnt signaling pathway (Modified from ref ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 PMC6610485__F2 Mechanisms by which bacteria influence cancer development and progression ENSG00000181847 ENSG00000168036 ENSG00000168610 PMC11937519__F4 Schematic overview of the proposed BDNF-TrkB-FRS3 signaling pathway, its role in energy balance regulation, and its connection to the leptin-melanocortin pathway ENSG00000115138 ENSG00000175426 ENSG00000166603 PMC9653759__F1 Antimicrobial Peptides Mediate Apoptosis by Changing Mitochondrial Membrane Permeability ENSG00000164430 PMC8633656__F1 Interleukin-17 family members in health and disease ENSG00000125810 ENSG00000056736 ENSG00000175104 ENSG00000163702 PMC6212405__F7 Distribution of the targets of Shenzhu Capsule on the compressed TNF signaling pathway ENSG00000112977 ENSG00000078747 ENSG00000167074 ENSG00000128342 ENSG00000168404 ENSG00000119912 ENSG00000127191 ENSG00000164305 PMC12115679__F4 Critical signaling pathways regulating TILs infiltration, proliferation, and anti-tumor response ENSG00000169245 ENSG00000111537 ENSG00000181847 ENSG00000167468 ENSG00000049768 ENSG00000026103 PMC5611503__F9 Signalling pathway of cytokine-cytokine receptor interaction signalling pathway ENSG00000104899 ENSG00000157404 ENSG00000099985 ENSG00000138798 ENSG00000183625 ENSG00000111321 ENSG00000145777 ENSG00000138071 ENSG00000187266 ENSG00000121966 ENSG00000226275 ENSG00000135960 ENSG00000117400 ENSG00000162892 ENSG00000146648 ENSG00000026103 PMC6346075__F1 Transsulfuration pathway PMC8700948__F1 Regulatory Effects and the Signaling Pathways of Natural Bioactive Compounds on Ferroptosis ENSG00000168003 ENSG00000196839 ENSG00000167468 ENSG00000072274 ENSG00000111684 PMC8217106__F4 Direct Targeting of Beta-Catenin in the Wnt Signaling Pathway: Current Progress and Perspectives ENSG00000138795 ENSG00000134982 ENSG00000196628 PMC8217106__F1 Direct Targeting of Beta-Catenin in the Wnt Signaling Pathway: Current Progress and Perspectives ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC3376449__F1 HER2 signaling pathway ENSG00000291971 ENSG00000198793 ENSG00000203710 ENSG00000168610 ENSG00000117322 PMC7450153__F1 CGAS-STING DNA sensing signaling pathway ENSG00000183735 PMC9318283__F9 Protective Effect of Eurotium cristatum Fermented Loose Dark Tea and Eurotium cristatum Particle on MAPK and PXR/AhR Signaling Pathways Induced by Electronic Cigarette Exposure in Mice ENSG00000106546 PMC7450153__F3 Protumor role of the cGAS-STING signaling pathway ENSG00000178860 ENSG00000109320 ENSG00000121807 PMC7205036__F11 Scheme summarizing the mechanism of the protective effect of astragalin and CGA on E ENSG00000170458 ENSG00000125538 ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC3704221__F1 miRNA biogenesis pathway ENSG00000092847 ENSG00000128191 ENSG00000113360 ENSG00000134698 ENSG00000123908 PMC8782480__F4 IPA canonical pathway, “Interferon signalling” ENSG00000159224 ENSG00000213928 ENSG00000111537 ENSG00000033800 ENSG00000125347 ENSG00000230034 PMC12059070__F7 Gemcitabine-induced cellular responses ENSG00000143799 ENSG00000145386 ENSG00000167900 ENSG00000112312 ENSG00000175054 ENSG00000134057 ENSG00000143476 ENSG00000167325 ENSG00000132383 ENSG00000171848 ENSG00000112029 ENSG00000106628 ENSG00000149554 ENSG00000139687 ENSG00000166803 PMC5711269__F1 Reverse cholesterol transport pathway ENSG00000130164 ENSG00000160179 PMC3534848__F8 A proposed mechanism by which hyperaldosteronism decreases pulmonary endothelial eNOS activation and NO• generation in PAH ENSG00000138336 ENSG00000179142 PMC4244643__F1 Biosynthesis of Isoprenoid building blocks ENSG00000067064 ENSG00000110921 ENSG00000148377 PMC4764764__F4 Transcriptome Sequencing (RNAseq) Enables Utilization of Formalin-Fixed, Paraffin-Embedded Biopsies with Clear Cell Renal Cell Carcinoma for Exploration of Disease Biology and Biomarker Development ENSG00000157554 ENSG00000125266 ENSG00000135547 ENSG00000117525 ENSG00000105329 ENSG00000119888 ENSG00000074181 ENSG00000198734 ENSG00000184916 ENSG00000123610 PMC6214770__F7 Proposed signaling model of crosstalk between NIS and PTEN signaling pathway ENSG00000198793 PMC12070570__F8 Schematic overviews of signaling pathways of enriched hypomethylated mRNAs in LMCI/Control ENSG00000130208 ENSG00000142192 ENSG00000189058 ENSG00000135218 ENSG00000002330 ENSG00000042832 ENSG00000196839 ENSG00000156026 ENSG00000183979 ENSG00000168040 ENSG00000281879 ENSG00000105664 ENSG00000119912 PMC7835216__F2 Emerging functions of branched ubiquitin chains ENSG00000078747 ENSG00000134982 ENSG00000104517 ENSG00000265972 PMC3785049__F3 Type I interferon induction is inhibited by paramyxovirus interferon-antagonist proteins at multiple stages ENSG00000183735 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000164342 PMC3737169__F2 MTX cellular pathway ENSG00000228716 ENSG00000116748 ENSG00000156110 ENSG00000136877 ENSG00000137563 ENSG00000116984 PMC9637033__F2 miRNAs: The Key Regulator of COVID-19 Disease ENSG00000130234 ENSG00000184012 ENSG00000113360 PMC11752968__F2 Targeting endoplasmic reticulum stress: an innovative therapeutic strategy for podocyte-related kidney diseases ENSG00000128272 ENSG00000100219 ENSG00000127191 PMC4372648__F1 Three core signaling pathways altered in malignant gliomas ENSG00000135446 ENSG00000134853 ENSG00000105810 ENSG00000118971 ENSG00000146648 ENSG00000196712 ENSG00000198625 PMC7595309__F2 Dual-function quorum-sensing systems in bacterial pathogens and symbionts ENSG00000036828 ENSG00000102003 PMC5754225__F1 PI3K-AKT-mTOR signaling pathways in glioblastoma ENSG00000169047 ENSG00000198793 ENSG00000118515 ENSG00000164327 PMC3776238__F2 Wnt regulation of larval NMJ differentiation PMC6177712__F2 Schematic depiction of cannabinoid and exemplar mono‐, sesqui‐, and diterpenoid biosynthesis ENSG00000197429 ENSG00000166278 PMC7990354__F1 Molecular mechanisms of renal aging ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000125538 ENSG00000047936 PMC2954189__F1 Simplified scheme of the double-edged role of Akt in tumor development ENSG00000132906 ENSG00000002330 ENSG00000198793 ENSG00000123374 PMC11767460__F7 Association Analysis of the Genomic and Functional Characteristics of Halotolerant Glutamicibacter endophyticus J2-5-19 from the Rhizosphere of Suaeda salsa ENSG00000166340 ENSG00000177971 ENSG00000140263 ENSG00000115718 PMC7461309__F1 Pollen-induced activation of the innate immune system and Th2 polarization ENSG00000102962 ENSG00000137033 ENSG00000102970 ENSG00000137265 ENSG00000107485 ENSG00000145777 ENSG00000136869 ENSG00000166090 PMC4841025__F5 Insulin signaling pathway ENSG00000109819 ENSG00000130957 ENSG00000196090 ENSG00000110395 ENSG00000100994 ENSG00000167941 ENSG00000125733 ENSG00000148204 ENSG00000079435 ENSG00000124253 ENSG00000026103 PMC4841025__F6 Chronic subordination stress selectively downregulates the insulin signaling pathway in liver and skeletal muscle but not in adipose tissue of male mice ENSG00000139330 ENSG00000099194 ENSG00000132170 PMC4841025__F7 Chronic subordination stress selectively downregulates the insulin signaling pathway in liver and skeletal muscle but not in adipose tissue of male mice ENSG00000198793 ENSG00000167074 ENSG00000213341 ENSG00000076555 ENSG00000127191 ENSG00000132356 ENSG00000168610 PMC7059166__F2 Canonical Wnt/B‐catenin(WBC) signalling pathway ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000133067 PMC6483058__F4 Visualization of resulting networks from Min-cut on the pathway of AD ENSG00000132906 ENSG00000142192 ENSG00000002330 ENSG00000178741 ENSG00000149782 ENSG00000159593 ENSG00000133318 ENSG00000169885 ENSG00000115310 ENSG00000143933 ENSG00000168040 ENSG00000010256 ENSG00000182621 ENSG00000137841 ENSG00000164305 ENSG00000221823 ENSG00000178607 ENSG00000176884 ENSG00000143801 ENSG00000006712 ENSG00000120868 ENSG00000119912 ENSG00000064012 ENSG00000026103 PMC6483058__F5 Illustration for cut-edges and the CTGs in AD pathway from KEGG ENSG00000132906 ENSG00000142192 ENSG00000178607 ENSG00000143801 ENSG00000120868 ENSG00000168040 ENSG00000026103 PMC7059166__F4 Cross talk dialogue between inflammatory and WBC‐signalling pathways in MPTP‐induced SVZ plasticity is lost with age ENSG00000168036 ENSG00000125084 PMC5309231__F3 Downstream effects analysis enables prediction of the effect of gene expression changes in each treatment ENSG00000132906 ENSG00000163235 ENSG00000166501 ENSG00000120889 ENSG00000277804 ENSG00000095794 PMC7186644__F1 Canonical Wnt/Beta-catenin signaling depends on the control of Beta-catenin degradation and translocation to the nucleus to activate target genes transcription ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC6256358__F1 Tankyrase function in cancer ENSG00000126016 ENSG00000177084 PMC7226605__F3 Anti-cancer effects and cell death pathways regulated by cannabinoids and the classical cannabinoid receptors ENSG00000128272 ENSG00000144895 ENSG00000101255 ENSG00000198793 PMC8055291__F5 Illustration of TNF signaling pathway influenced by major putative targets of GBKC ENSG00000108691 ENSG00000125538 ENSG00000056558 ENSG00000131323 ENSG00000100985 ENSG00000127191 ENSG00000073756 PMC8497507__F7 Schematic showing the roles of mGluR2/3, mGluR1 and DGK in controlling responses evoked by MF activation ENSG00000136267 ENSG00000164082 ENSG00000058866 ENSG00000138741 ENSG00000101333 ENSG00000157542 PMC1479816__F3 Pathways involved in mesenchymal cell proliferation and differentiation induced by G protein coupled receptors (GPCRs) ENSG00000198793 ENSG00000163914 PMC5987716__F2 SOD-dependent ROS signaling in mammalian cells ENSG00000284774 ENSG00000291971 ENSG00000105227 PMC6131212__F7 Activation mechanisms of the Hippo kinase signaling cascade ENSG00000163681 ENSG00000150457 ENSG00000131023 PMC4834478__F8 microRNA let-7c is essential for the anisomycin-elicited apoptosis in Jurkat T cells by linking JNK1/2 to AP-1/STAT1/STAT3 signaling ENSG00000115415 ENSG00000168610 PMC4101832__F2 Processes and outcomes involving leptin, OB-R, Notch1, Notch4, IL-1R tI, JAG1, DLL4, VEGF, VEGFR2 (KDR), EGFR, AR and Ki67 (MKi67 gene) in the development of breast neoplasms ENSG00000148773 ENSG00000128917 ENSG00000112715 ENSG00000150630 PMC4701060__F1 Signal transduction pathway like mitogen-activated protein kinase/extracellular signal-regulated kinases signaling pathway ENSG00000002330 ENSG00000291971 ENSG00000134982 ENSG00000010810 ENSG00000135446 ENSG00000177606 ENSG00000168036 ENSG00000123374 ENSG00000168040 ENSG00000128602 ENSG00000168610 PMC2744676__F2 Diagram depicting proliferative and survival signaling pathways in cells ENSG00000124102 ENSG00000002330 ENSG00000135446 ENSG00000138798 ENSG00000198793 ENSG00000105810 ENSG00000146648 PMC7313395__F3 Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis of the Cell Cycle Pathway in Trypanosoma cruzi-infected myoblasts ENSG00000145604 ENSG00000149311 ENSG00000101972 ENSG00000164754 PMC3241824__F1 Operation of the mammalian Hippo pathway in mouse intestinal epithelium and human colon cancer ENSG00000168036 PMC7313395__F2 Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis of the JAK/STAT Pathway in Trypanosoma cruzi-infected myoblasts ENSG00000119535 ENSG00000198793 ENSG00000033800 ENSG00000137193 ENSG00000108342 ENSG00000131095 ENSG00000105639 ENSG00000175505 ENSG00000168610 ENSG00000105397 ENSG00000115415 ENSG00000087842 ENSG00000022267 PMC8632942__F6 Coordination of retrotransposons and type I interferon with distinct interferon pathways in dermatomyositis, systemic lupus erythematosus and autoimmune blistering disease ENSG00000159128 ENSG00000187608 ENSG00000105397 ENSG00000089127 ENSG00000115415 ENSG00000185436 ENSG00000185745 ENSG00000115267 ENSG00000027697 ENSG00000125347 ENSG00000276561 ENSG00000142166 PMC5362109__F2 Autoimmunity in vitiligo is driven by the IFN-Gamma-CXCL10 cytokine signaling pathway ENSG00000169245 ENSG00000186810 ENSG00000138755 PMC7272051__F3 Unveiling functional motions based on point mutations in biased signaling systems: A normal mode study on nerve growth factor bound to TrkA ENSG00000002330 ENSG00000169047 ENSG00000117322 PMC11788965__F1 Simplified brassinosteroids (BR) biosynthesis and signalling pathways ENSG00000109814 ENSG00000108582 ENSG00000110934 ENSG00000105227 PMC11514642__F9 Abnormal expression of MECOM in uterine corpus endometrial carcinoma and its mechanistic involvement in regulating the Hippo signaling pathway and affecting cell cycle and apoptosis ENSG00000049768 PMC4165418__F3 AKT's role in the NER pathway ENSG00000012061 ENSG00000132646 ENSG00000136936 PMC4165418__F4 AKT suppresses the HR pathway and activates the NHEJ pathway via many mechanisms ENSG00000149311 ENSG00000012048 ENSG00000051180 ENSG00000112130 PMC11276987__F3 Maladaptive UPR and endoplasmic reticulum (ER) stress-mediated inflammation ENSG00000128272 ENSG00000205221 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC3499080__F2 Alterations in the NRF2 canonical pathway in livers of mice treated with TMHF ENSG00000166794 ENSG00000167996 ENSG00000165280 ENSG00000125656 ENSG00000176153 ENSG00000023909 ENSG00000135624 ENSG00000138356 ENSG00000101557 ENSG00000079999 PMC11276987__F4 Unfolded protein response signaling with their regulating microRNAs ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC8021562__F6 TOPORS-AS1 regulated by VDR, interacting with hnRNPA2B1, and inhibiting the Wnt/Beta-catenin signaling ENSG00000122566 ENSG00000134982 ENSG00000168036 PMC3137930__F8 Analysis of p53 target genes in melanocytes treated with Nutlin-3 for 18 h ENSG00000104499 ENSG00000148400 ENSG00000118263 ENSG00000137193 ENSG00000167900 ENSG00000111665 ENSG00000065328 ENSG00000077150 ENSG00000188976 ENSG00000149136 ENSG00000143476 ENSG00000132646 ENSG00000139842 ENSG00000123374 ENSG00000112378 ENSG00000078237 ENSG00000284194 ENSG00000283060 ENSG00000155090 PMC11276987__F2 Schema of pathways producing and utilizing endoplasmic reticulum (ER)-derived H2O2 ENSG00000086991 ENSG00000164294 PMC9163972__F10 Bindarit Reduces Bone Loss in Ovariectomized Mice by Inhibiting CCL2 and CCL7 Expression via the NF‐KB Signaling Pathway ENSG00000108691 ENSG00000108688 ENSG00000121807 PMC9655277__F1 Immune Modulation by Myeloid-Derived Suppressor Cells in Diabetic Kidney Disease ENSG00000152266 ENSG00000198793 ENSG00000047936 PMC11276987__F7 Adiponectin signal transduction [118] ENSG00000157500 ENSG00000159346 ENSG00000285070 PMC5340150__F1 Autophagy in infection, inflammation, and immunity ENSG00000162711 ENSG00000167207 ENSG00000163568 ENSG00000125538 ENSG00000198793 ENSG00000189403 ENSG00000107201 ENSG00000175104 ENSG00000145782 PMC11276987__F5 Cellular Senescence and Extracellular Vesicles in the Pathogenesis and Treatment of Obesity—A Narrative Review ENSG00000162711 ENSG00000284774 ENSG00000198793 ENSG00000096717 PMC7237121__F1 CDK4/6 inhibitors and possible combined therapy with CDK4/6 inhibitors ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC11763662__F1 Various cell signaling cascades involved in breast cancer ENSG00000106571 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000087586 ENSG00000133961 ENSG00000128602 ENSG00000168610 ENSG00000146648 PMC4281841__F2 Involvement of the IRE1Alpha-XBP1 Pathway and XBP1s-Dependent Transcriptional Reprogramming in Metabolic Diseases ENSG00000062282 ENSG00000026103 ENSG00000262243 PMC4281841__F3 Involvement of the IRE1Alpha-XBP1 Pathway and XBP1s-Dependent Transcriptional Reprogramming in Metabolic Diseases ENSG00000169047 PMC3478884__F1 Emerging role of nuclear architecture in DNA repair and genome maintenance ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000112130 PMC3711797__F4 Mathematical model of type I IFN signaling pathway ENSG00000115415 ENSG00000125347 PMC1304358__F3 Examples of extreme signaling pathways of the JAK-STAT signaling network ENSG00000184995 PMC7128030__F1 Bile acid synthesis ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC7867637__F2 High glucose on fibroblast activity and function ENSG00000113140 ENSG00000125538 PMC11763662__F6 Representative molecular targets in breast cancer, along with the corresponding immunotherapeutic and targeted treatment approach ENSG00000291971 ENSG00000134982 ENSG00000135446 ENSG00000138798 ENSG00000105810 ENSG00000146648 PMC7785232__F6 GAS6 signaling tempers Th17 development in patients with multiple sclerosis and helminth infection ENSG00000153208 ENSG00000111537 ENSG00000158481 ENSG00000026508 PMC11763662__F5 Molecular Insights on Signaling Cascades in Breast Cancer: A Comprehensive Review ENSG00000177575 ENSG00000108691 ENSG00000067057 ENSG00000105329 ENSG00000163739 ENSG00000108924 ENSG00000164483 ENSG00000168610 ENSG00000159399 PMC11763662__F3 Culmination of signaling pathways in the tumor stroma microenvironment involving cancer-associated fibroblasts (CAFs), adipocytes, and mast cells ENSG00000108691 ENSG00000135218 ENSG00000161921 ENSG00000163739 ENSG00000138798 ENSG00000108700 ENSG00000163734 ENSG00000134853 ENSG00000078098 PMC9095358__F9 Dietary Fatty Acid Regulation of the NLRP3 Inflammasome via the TLR4/NFKB Signaling Pathway Affects Chondrocyte Pyroptosis ENSG00000278718 ENSG00000162711 ENSG00000172936 PMC8802127__F7 Long non-coding RNA HNF1A-AS1 induces 5-FU resistance of gastric cancer through miR-30b-5p/EIF5A2 pathway ENSG00000145321 ENSG00000163577 PMC9065418__F1 Association of TGFB Canonical Signaling-Related Core Genes With Aortic Aneurysms and Aortic Dissections ENSG00000170365 ENSG00000137834 PMC7061757__F8 Crosstalk between EGRF inhibition and TLR4 pathways in HNSCC ENSG00000291971 ENSG00000172936 ENSG00000136869 PMC7542117__F5 Core HIF-1 signaling pathway in THSWD against DR ENSG00000134086 ENSG00000072274 ENSG00000136869 ENSG00000112715 ENSG00000007171 ENSG00000140443 PMC3287012__F1 Signaling through CD44: hyaluronan binding to a receptor such as CD44 or RHAMM will cause a conformational change in the receptor ENSG00000019991 ENSG00000105401 ENSG00000163914 ENSG00000026508 ENSG00000198670 ENSG00000137845 PMC2838843__F3 PTEN signaling pathway ENSG00000002330 PMC3844070__F1 The IFNG signaling pathway ENSG00000159128 ENSG00000115415 ENSG00000027697 PMC5964095__F10 Salvianolic acid B inhibits glycolysis in oral squamous cell carcinoma via targeting PI3K/AKT/HIF-1A signaling pathway ENSG00000198793 ENSG00000159399 PMC6299648__F5 Oxidative status and leptin signalling pathway in human mammary epithelial cells ENSG00000168610 PMC11015925__F4 Circulating Levels of HOTAIR- lncRNA Are Associated with Disease Progression and Clinical Parameters in Type 2 Diabetes Patients ENSG00000109819 ENSG00000140992 ENSG00000104365 ENSG00000050748 ENSG00000150907 ENSG00000168610 PMC6131212__F1 Activation mechanisms of the Hippo kinase signaling cascade ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC9925018__F8 KDM4D and Hippo signaling pathway in the regulation of cell cycle activities ENSG00000178999 ENSG00000136997 ENSG00000145321 ENSG00000186280 PMC2913455__F7 E-selectin–mediated slow rolling ENSG00000026508 ENSG00000010671 PMC7546902__F4 Engineered biosynthetic pathway for geraniol in S ENSG00000067064 ENSG00000197429 ENSG00000179632 ENSG00000123268 PMC8481335__F2 Mitochondria in ferroptosis ENSG00000135423 ENSG00000156709 ENSG00000102967 ENSG00000136381 ENSG00000182511 ENSG00000164430 ENSG00000155287 ENSG00000147454 ENSG00000116688 ENSG00000167468 ENSG00000122873 ENSG00000196365 ENSG00000136003 ENSG00000145354 ENSG00000171109 ENSG00000060762 PMC6538180__F3 Transcriptional changes after herpes simplex virus type 1 infection in human trabecular meshwork cells ENSG00000105329 ENSG00000138166 ENSG00000143878 ENSG00000116717 ENSG00000162772 ENSG00000163660 PMC8481335__F1 Core mechanisms of ferroptosis ENSG00000148346 ENSG00000151726 ENSG00000135218 ENSG00000151012 ENSG00000116044 ENSG00000102967 ENSG00000184381 ENSG00000168003 ENSG00000167468 ENSG00000111684 ENSG00000042286 ENSG00000122873 ENSG00000005381 ENSG00000127948 ENSG00000123983 PMC5562070__F1 TGFB signaling induced apoptosis is modulated by the UPR cascade ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC3430120__F2 Summary of pathways controlling muscle protein synthesis (MPS) and muscle protein breakdown (MPB) ENSG00000111049 ENSG00000198793 PMC4548225__F2 LGR4-Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000140575 ENSG00000183579 ENSG00000168036 PMC8481335__F4 Endoplasmic reticulum in ferroptosis ENSG00000151012 ENSG00000198793 ENSG00000099194 ENSG00000079999 ENSG00000168003 ENSG00000128272 ENSG00000164430 ENSG00000144895 ENSG00000116688 ENSG00000167468 ENSG00000111684 ENSG00000171109 ENSG00000123983 ENSG00000128965 PMC7647682__F3 Putative molecular mechanisms and signaling pathways that may regulate the endothelial-to-mesenchymal transition (EndoMT) process in systemic sclerosis ENSG00000168036 PMC9583547__F1 Differential distribution of steroid hormone signaling networks in the human choroid-retinal pigment epithelial complex ENSG00000151834 ENSG00000145864 ENSG00000129214 PMC3313080__F2 Endoplasmic Reticulum Stress, the Unfolded Protein Response, Autophagy, and the Integrated Regulation of Breast Cancer Cell Fate ENSG00000128272 ENSG00000144895 ENSG00000145321 ENSG00000132478 ENSG00000145782 PMC12165590__F3 Applications of extracellular vesicles in osteoporosis ENSG00000164932 ENSG00000105472 ENSG00000112715 PMC9583547__F3 Differential distribution of steroid hormone signaling networks in the human choroid-retinal pigment epithelial complex ENSG00000291971 ENSG00000169032 ENSG00000146648 PMC8578048__F2 Long Non-Coding RNAs in Oral Submucous Fibrosis: Their Functional Mechanisms and Recent Research Progress ENSG00000005882 ENSG00000056558 ENSG00000205250 ENSG00000108821 PMC5394545__F5 High-Throughput Sequencing and Co-Expression Network Analysis of lncRNAs and mRNAs in Early Brain Injury Following Experimental Subarachnoid Haemorrhage ENSG00000169291 ENSG00000239732 ENSG00000170965 ENSG00000144410 ENSG00000133454 ENSG00000168040 ENSG00000150455 ENSG00000143387 PMC9547585__F7 The let-7f-5p regulates the PI3K/AKT/COX2 signaling pathway in forest musk deer lung fibroblast cell ENSG00000030304 ENSG00000121879 PMC6597188__F1 TNF-driven cell death in donor organ as a barrier to immunological tolerance ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC5011664__F1 Canonical wingless/int-1signaling pathway ENSG00000166167 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4039567__F8 De novo expression of circulating biglycan evokes an innate inflammatory tissue response via MyD88/TRIF pathways ENSG00000108691 ENSG00000081041 ENSG00000163739 ENSG00000172936 ENSG00000136869 ENSG00000062485 PMC5011664__F2 Non-canonical wingless/int-1 signaling pathway ENSG00000169071 ENSG00000291971 ENSG00000010810 ENSG00000198793 PMC4644789__F1 Interplay of TrkB and GR signaling pathways in the CNS ENSG00000169291 ENSG00000288269 ENSG00000145321 ENSG00000160741 PMC5836295__F1 Regulation of IL-33/ST2 pathway by sST2, IL-33 neutralizing antibodies, and GSK3Beta-regulated ubiquitin-proteasome system ENSG00000137033 ENSG00000099364 PMC7232267__F5 Micro ribonucleic acid (miRNA) cross‐talk between miR 29 and miR let‐7 in the anti‐endothelial mesenchymal transition action of N‐acetyl‐seryl‐aspartyl‐lysyl‐proline (AcSDKP) ENSG00000197635 ENSG00000077782 PMC8047194__F1 Hippo signaling pathways in Drosophila and mammals ENSG00000186575 ENSG00000144560 ENSG00000277273 ENSG00000165323 ENSG00000131023 PMC7232267__F4 Fibroblast growth factor receptor 1 (FGFR1)–B klotho complex plays roles in endothelial homeostasis ENSG00000105550 ENSG00000077782 PMC4975621__F5 CAR targeted miRNA and mRNA in liver cancer ENSG00000147162 ENSG00000107798 ENSG00000103222 ENSG00000186480 ENSG00000169710 ENSG00000140943 ENSG00000255974 ENSG00000285070 ENSG00000168610 ENSG00000023839 PMC8188209__F11 Physiological and Pathological Factors Affecting Drug Delivery to the Brain by Nanoparticles ENSG00000288512 ENSG00000203710 ENSG00000182326 PMC9100923__F1 Prenatal Choline Supplementation Alters One Carbon Metabolites in a Rat Model of Periconceptional Alcohol Exposure ENSG00000124275 ENSG00000116984 ENSG00000133027 PMC3245622__F1 PI3K/Akt signaling pathway is involved in several human cancers ENSG00000002330 ENSG00000198793 PMC9601721__F3 Whole-Exome Sequencing Reveals Pathogenic SIRT1 Variant in Brain Arteriovenous Malformation: A Case Report ENSG00000145604 ENSG00000149311 ENSG00000087095 ENSG00000171105 ENSG00000127528 ENSG00000123374 ENSG00000145782 ENSG00000168610 ENSG00000197601 PMC6902869__F1 Tumor-targeting bacteria engineered to fight cancer ENSG00000111537 ENSG00000170458 ENSG00000187554 ENSG00000125538 ENSG00000136869 PMC9553029__F3 NMDARs mediate peripheral and central sensitization contributing to chronic orofacial pain ENSG00000042832 ENSG00000110218 ENSG00000196689 PMC7461546__F5 NME protein-histidine kinase functions ENSG00000131473 ENSG00000141068 ENSG00000107902 ENSG00000163541 ENSG00000274348 ENSG00000146648 PMC11194209__F1 Major abnormal signaling pathways in TNBC ENSG00000169291 ENSG00000281324 ENSG00000162337 ENSG00000148400 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000146648 ENSG00000155760 PMC4748524__F1 TLR signaling pathway genes ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC7272661__F2 Graphic illustration of molecular autophagic pathway ENSG00000177169 ENSG00000110497 ENSG00000152348 ENSG00000123395 ENSG00000198382 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000163820 ENSG00000057663 PMC3872270__F2 Many ways to inactivate the p53 pathway in cancer ENSG00000149311 PMC9284706__F2 Targeting purinergic pathway to enhance radiotherapy-induced immunogenic cancer cell death ENSG00000163599 ENSG00000110218 ENSG00000026103 PMC7033608__F3 Possible mechanism of Wilms tumor 1 antisense RNA (WT1-AS) functioning ENSG00000170802 PMC7602874__F2 Schematic diagram of the role of the cGAS-STING pathway in cancer immunity ENSG00000173638 PMC7602874__F1 Cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes (cGAS-STING) signalling pathway ENSG00000183735 ENSG00000164430 ENSG00000197594 PMC3998523__F1 Sphingolipid pathway and subcellular localization of sphingolipid enzymes ENSG00000157933 ENSG00000102172 PMC7876374__F2 Effect of EGCG on miRNA and Ca2+signaling in T cells ENSG00000293604 ENSG00000198793 ENSG00000105656 ENSG00000109689 PMC4438218__F1 Proposed model for the regulatory role of methenyl-dH4MPT in methylotrophic metabolism in M ENSG00000261701 PMC9118050__F2 Cancer‐associated fibroblasts in breast cancer: Challenges and opportunities ENSG00000107562 ENSG00000081041 ENSG00000154764 ENSG00000143815 ENSG00000163739 ENSG00000164938 ENSG00000026508 ENSG00000168036 ENSG00000265972 ENSG00000083799 ENSG00000078098 ENSG00000121966 PMC3241001__F1 Pharmacologic Induction of CD8+ T Cell Memory: Better Living Through Chemistry ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC9843445__F3 Major roles of the circadian clock in cancer ENSG00000198793 PMC5213309__F5 Soluble tumor-derived signals change the phenotype of the tumor-associated macrophage, by induction of the mTOR pathway and glycolysis, and epigenetic changes ENSG00000198793 PMC4047762__F6 ALK1 Signaling Inhibits Angiogenesis by Cooperating with the Notch Pathway ENSG00000170365 ENSG00000135547 ENSG00000168214 ENSG00000128917 ENSG00000125968 PMC4248790__F4 Piwi proteins and piRNAs step onto the systems biology stage ENSG00000142182 ENSG00000095627 ENSG00000088305 ENSG00000077800 ENSG00000073146 PMC6726984__F2 SnoRD126 activates the PI3K-AKT signaling pathway through FGFR2 and snoRD50A/B and affects the MAPK signaling cascades ENSG00000066468 ENSG00000005882 ENSG00000136997 PMC6329944__F1 Three phases of tooth eruption, preeruptive, intraosseous, and supraosseous, require signaling in the PTHrP/PTH1R pathway ENSG00000184371 PMC5751231__F7 Regulation of miRNA expression in response to maternal disease and stress ENSG00000092054 ENSG00000185532 ENSG00000118971 ENSG00000282899 PMC7992277__F10 Na+ controls hypoxic signalling by the mitochondrial respiratory chain ENSG00000196531 ENSG00000156026 ENSG00000084774 PMC9580515__F5 Effect of micro/nano-sheet array structures on the osteo-immunomodulation of macrophages ENSG00000198793 ENSG00000168610 PMC7356105__F2 Illustration depicts the localization of the gene products by cellular compartmentalization and indicates the downregulated expression of NF-kappaB signaling pathway as an effect of vitamin E formulation treatment on heat killed C ENSG00000226275 ENSG00000163235 ENSG00000138798 ENSG00000150455 ENSG00000127191 PMC7728999__F4 LncRNA XLOC_221242 regulates the expression of DNER, which is the key factor of Notch signal pathway ENSG00000187957 ENSG00000168214 ENSG00000170558 ENSG00000113558 ENSG00000168036 PMC3604104__F5 Gene Expression Networks Underlying Ovarian Development in Wild Largemouth Bass (Micropterus salmoides) ENSG00000140992 ENSG00000168036 PMC3243113__F10 MULTIPLE WAYS TO DIE: DELINEATION OF THE UNFOLDED PROTEIN RESPONSE AND APOPTOSIS INDUCED BY SURFACTANT PROTEIN C BRICHOS MUTANTS ENSG00000128272 ENSG00000127191 PMC9013399__F1 Significance of NAD + metabolites and nicotinamide N-methyltransferase in chronic kidney disease ENSG00000105835 ENSG00000278488 PMC4935227__F2 WWOX regulates multiple signaling pathways ENSG00000004975 ENSG00000291971 ENSG00000164690 ENSG00000128602 ENSG00000178568 PMC8360401__F2 Ischemic postconditioning for stroke treatment: current experimental advances and future directions ENSG00000002330 ENSG00000125538 ENSG00000198793 ENSG00000168036 ENSG00000136869 ENSG00000171791 PMC4935227__F3 The potential role of WWOX in anticancer drug-induced cancer cell apoptosis ENSG00000198793 ENSG00000057663 PMC8036776__F1 NF-kB pathway targeted by GSH ENSG00000125538 PMC3155407__F1 Murine model of the multiple actions to suppress immune surveillance of exosomes released from neoplastic cells ENSG00000170458 ENSG00000049768 ENSG00000105639 PMC4159787__F3 The relationship between RAGE and neurite outgrowth after spinal cord injury ENSG00000070831 ENSG00000189403 PMC4724957__F3 Metabolic pathway map of Parachlorella kessleri ENSG00000126775 ENSG00000102977 PMC8708558__F2 Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression ENSG00000148400 ENSG00000168487 ENSG00000140545 ENSG00000120913 ENSG00000198113 ENSG00000136378 ENSG00000292234 ENSG00000159674 ENSG00000196923 ENSG00000083444 ENSG00000288512 ENSG00000140511 ENSG00000138080 PMC2533793__F10 Model for negative regulation of Wnt signaling pathway by corepressors SMRT and NCoR ENSG00000171720 ENSG00000168036 ENSG00000196628 PMC5926502__F4 BIOGF1K, a compound K-rich fraction of ginseng, plays an antiinflammatory role by targeting an activator protein-1 signaling pathway in RAW264.7 macrophage-like cells ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000167900 PMC4013446__F2 Functional significance of differentially expressed miRNAs—miRNA-512-5p, 190a and 200b-3p (Ingenuity pathway analysis) ENSG00000121989 ENSG00000107263 ENSG00000157764 ENSG00000130699 ENSG00000156531 ENSG00000076641 ENSG00000166484 ENSG00000174106 ENSG00000109756 PMC7457075__F7 Possible mechanism of anti-inflammatory effect of OEA on colitis ENSG00000125538 ENSG00000127191 PMC4629442__F1 EGFR and its signal pathway ENSG00000002330 ENSG00000163235 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000171791 ENSG00000168610 ENSG00000146648 PMC3548163__F2 Modes of action of environmental risk factors for autism at excitatory synapses in the CNS ENSG00000183840 ENSG00000140443 PMC5964985__F2 Atrial fibrillation genes in calcium signaling and ECM–receptor interaction ENSG00000135218 ENSG00000259207 ENSG00000142798 ENSG00000122420 ENSG00000050628 ENSG00000169439 ENSG00000115221 ENSG00000198626 ENSG00000182621 ENSG00000102468 ENSG00000133019 ENSG00000053747 ENSG00000213949 ENSG00000198838 ENSG00000188157 ENSG00000166501 ENSG00000197943 ENSG00000115232 ENSG00000146648 ENSG00000178568 ENSG00000155657 ENSG00000101333 PMC10933535__F1 Metabolic reprogramming and signalling cross-talks in tumour–immune interaction: a system-level exploration ENSG00000102962 ENSG00000291603 ENSG00000111537 ENSG00000102871 ENSG00000134982 ENSG00000138798 ENSG00000102970 ENSG00000049768 ENSG00000127191 ENSG00000026103 PMC6321258__F1 Interaction between metabolism and histone acetylation and DNA/histone methylation ENSG00000131473 PMC2760069__F1 Brothers and Sisters: Molecular insights into arterial-venous heterogeneity ENSG00000196411 ENSG00000176692 ENSG00000135547 ENSG00000148400 ENSG00000285438 ENSG00000037280 ENSG00000118257 ENSG00000203883 PMC7324687__F2 Dopamine interaction with adenosine and NMDA signaling ENSG00000177606 ENSG00000132326 ENSG00000179094 PMC4650770__F1 Biosynthetic pathways of histo–blood group antigens ENSG00000069482 ENSG00000196371 ENSG00000187837 ENSG00000130383 PMC7322524__F1 Cell death pathways triggered by DNA sensors ENSG00000278718 ENSG00000183735 ENSG00000164430 ENSG00000163568 ENSG00000125538 PMC7322524__F2 Cell death pathways triggered by RNA sensors ENSG00000124256 ENSG00000183735 ENSG00000088888 ENSG00000137275 ENSG00000133116 ENSG00000168040 ENSG00000168404 ENSG00000285379 ENSG00000164342 PMC8972192__F2 Exploration of Novel Pathways Underlying Irreversible Electroporation Induced Anti-Tumor Immunity in Pancreatic Cancer ENSG00000239732 ENSG00000111537 ENSG00000115415 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000076604 PMC5897459__F2 Biosynthetic pathway of thylakoid glycerolipids from phosphatidic acid (PA) in Arabidopsis thaliana ENSG00000163624 ENSG00000184207 ENSG00000101290 PMC8744307__F2 Inflammasomes in vascular cognitive impairment ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000091592 ENSG00000091106 PMC5758348__F2 Illustration of the cellular and molecular targets of total and individual Panax notoginseng saponins (PNS) on neural cells destroyed by Alzheimer's disease ENSG00000162924 ENSG00000139687 PMC6830763__F1 Brief description of the interaction of a CD4+ T cell with B cells ENSG00000111537 PMC8292787__F1 Allergic Aspects of IgG4-Related Disease: Implications for Pathogenesis and Therapy ENSG00000137033 ENSG00000186716 ENSG00000173599 ENSG00000145777 PMC8700074__F1 Aryl Hydrocarbon Receptor Activation in Inflammatory Chronic Skin Diseases ENSG00000162924 ENSG00000140465 ENSG00000106546 PMC3782218__F1 Role of the proteins and mediators involved in iron homeostasis and impact of hereditary hemochromatosis protein mutations in chronic kidney disease ENSG00000010704 ENSG00000106327 ENSG00000105697 ENSG00000168610 PMC7356105__F3 TNF pathway inhibition in HGF in response to C ENSG00000162889 ENSG00000175899 ENSG00000132478 ENSG00000127191 PMC10487821__F9 Activation of the Wnt/Beta-catenin signaling pathway via lithium released from the IPN-Li hydrogel ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6818723__F14 Hypothetical signaling network integrating top genes identified through Rasch analysis ENSG00000171720 ENSG00000242252 ENSG00000010810 ENSG00000198793 ENSG00000198576 ENSG00000150093 ENSG00000141564 ENSG00000036828 ENSG00000136040 ENSG00000181026 ENSG00000182667 PMC2674702__F1 Metabolism of extracellular and intracellular bioactive lipids ENSG00000198670 ENSG00000166278 PMC5364998__F2 Paradoxical Role of High Mobility Group Box 1 in Glioma: A Suppressor or a Promoter? ENSG00000239732 ENSG00000189403 PMC8285047__F2 Nitric oxide in orthodontic tooth movement (Review) ENSG00000291971 ENSG00000168036 PMC7906391__F5 Hippocampal transcriptome-wide association study and neurobiological pathway analysis for Alzheimer’s disease ENSG00000142192 PMC1571327__F6 FGF, Wnt and Tbx3 in epithelial–mesenchymal interactions regulating mammary gland initiation ENSG00000070193 ENSG00000138795 ENSG00000135111 ENSG00000077782 PMC6295738__F4 The enzymes of bile acid synthesis ENSG00000242110 ENSG00000276559 PMC3612991__F2 Harmonies Played by TGFB in Stem Cell Biology ENSG00000183691 ENSG00000156574 ENSG00000168036 ENSG00000128342 PMC2776288__F2 Crosstalk between ionizing radiation-induced apoptosis and NFKB pathway ENSG00000149311 ENSG00000127191 PMC2776288__F3 Crosstalk between apoptosis and NFKB signaling by IAP-antagonist ENSG00000127191 PMC3362995__F5 The WNT10b and galanin-mediated signaling pathways linked to adipogenesis ENSG00000120057 ENSG00000155011 PMC2662368__F2 T cell differentiation proceeds along distinct pathways following antigen presentation by DCs ENSG00000138378 ENSG00000111537 ENSG00000107485 ENSG00000049768 ENSG00000168610 ENSG00000106546 PMC12133554__F2 Molecular mechanisms of LGR4 in tumor bone metastasis ENSG00000162337 ENSG00000168036 ENSG00000219200 PMC2704819__F2 Catabolic pathways encoded by the T ENSG00000127948 PMC12133554__F1 Molecular mechanisms of LGR4 in bone metabolism ENSG00000169218 ENSG00000128272 ENSG00000162337 ENSG00000168036 ENSG00000131196 PMC8755460__F3 K63 ubiquitination in immune signaling ENSG00000162711 ENSG00000137275 ENSG00000049768 ENSG00000127191 ENSG00000276561 ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000186716 ENSG00000160703 ENSG00000142405 ENSG00000131323 ENSG00000175104 PMC9452849__F13 Hope for bone regeneration: The versatility of iron oxide nanoparticles ENSG00000291355 ENSG00000134853 ENSG00000168036 ENSG00000077782 PMC4082789__F1 Exploiting sulphur-carrier proteins from primary metabolism for 2-thiosugar biosynthesis ENSG00000039537 ENSG00000166278 PMC7554980__F2 mRNA in vitro transcription and innate immunity activation ENSG00000088888 ENSG00000144895 ENSG00000172936 ENSG00000107201 ENSG00000135828 ENSG00000276561 ENSG00000164342 PMC3670240__F1 Ubiquitin-mediated regulation of JAK-STAT signaling in embryonic stem cells ENSG00000136997 ENSG00000135111 ENSG00000171206 ENSG00000121236 ENSG00000128342 ENSG00000168610 PMC8927697__F4 Inflammation and Cancer: From the Development of Personalized Indicators to Novel Therapeutic Strategies ENSG00000189403 PMC2993794__F1 Stimuli and factors involved in yeast chronological aging ENSG00000115317 PMC7072724__F8 PP2A regulation by S67/S62-phosphorylated ENSA/ARPP19 in human platelets and the impact of PKA/PKG on it ENSG00000128989 ENSG00000143420 PMC8832032__F4 Mitochondrial Quality Control: A Pathophysiological Mechanism and Therapeutic Target for Stroke ENSG00000152348 ENSG00000183735 ENSG00000158828 ENSG00000145782 ENSG00000247077 ENSG00000057663 PMC3185810__F2 Alteration of the IFN-I signaling pathway by HTLV-1 ENSG00000105397 ENSG00000142166 PMC6330656__F1 Targeting ERBB Activation Mediated by CD74-NRG1 ENSG00000019582 ENSG00000065361 PMC7823493__F2 Synovial membrane and bone interactions in rheumatoid arthritis ENSG00000111537 ENSG00000198670 PMC9158144__F7 Metallothionein 2A (MT2A) controls cell proliferation and liver metastasis by controlling the MST1/LATS2/YAP1 signaling pathway in colorectal cancer ENSG00000125148 ENSG00000150457 PMC3185810__F1 Interplay between HTLV-1 and the type-I interferon (IFN-I) induction pathway ENSG00000239732 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC6361815__F1 Different types of GSLs ENSG00000176597 ENSG00000135454 ENSG00000184389 ENSG00000148154 PMC10216109__F2 Melatonin antioxidant properties and tryptophan metabolic pathway ENSG00000144712 ENSG00000105227 PMC4043215__F1 Hypoxia-Activated Pathways Leading to Cancer Stem Cell Maintenance ENSG00000272398 ENSG00000204531 PMC6181033__F7 Proposed model for the role of ZmbZIP4 in maize root development and stress response ENSG00000134287 ENSG00000099246 PMC2695822__F9 Display of genes with high expression in IVF embryos ENSG00000105656 ENSG00000129460 PMC10243716__F2 Ferroptosis as a vulnerability in cancer ENSG00000186575 ENSG00000134086 ENSG00000167468 ENSG00000072274 ENSG00000086991 ENSG00000146648 ENSG00000102967 ENSG00000135245 PMC4890337__F10 MWCNTg promote the EMT through the TGF-Beta-mediated Akt/GSK-3B/SNAIL-1 pathway ENSG00000163235 ENSG00000168036 PMC8425214__F1 Regulatory networks of the Hippo signaling pathway in cancer development ENSG00000150457 ENSG00000131023 PMC5015648__F2 AB-crystallin negatively regulates multiple steps in the intrinsic (mitochondrial) apoptotic pathway ENSG00000132906 ENSG00000164305 PMC2773630__F6 Molecular interactions during pheromone induced cell polarization ENSG00000070831 ENSG00000197601 PMC8425214__F4 Regulatory networks of the Hippo signaling pathway in cancer development ENSG00000164879 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC6206039__F7 Scheme summarizing the inhibition of cisplatin-induced nephrotoxicity by maltol via the down-regulation of AMPK through PI3K/Akt pathway ENSG00000132906 ENSG00000102871 ENSG00000198793 ENSG00000168040 ENSG00000127191 ENSG00000164305 PMC8425214__F2 Regulatory networks of the Hippo signaling pathway in cancer development ENSG00000126016 ENSG00000128272 ENSG00000181788 ENSG00000163914 ENSG00000196470 ENSG00000131023 PMC5597640__F9 Model for replication stress and its aftermath in the absence of BRCA2 ENSG00000051180 ENSG00000139618 PMC8425214__F3 Regulatory networks of the Hippo signaling pathway in cancer development ENSG00000183735 ENSG00000088888 ENSG00000291971 ENSG00000131023 PMC9393183__F2 Targeting thromboinflammation in COVID-19 – A narrative review of the potential of C1 inhibitor to prevent disease progression ENSG00000291559 ENSG00000166278 ENSG00000182326 PMC9393183__F3 Targeting thromboinflammation in COVID-19 – A narrative review of the potential of C1 inhibitor to prevent disease progression ENSG00000291559 ENSG00000130234 ENSG00000122194 PMC11265800__F6 Signaling pathways in melanoma cells and tissue ENSG00000087245 ENSG00000173546 PMC2887297__F1 Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease ENSG00000128272 ENSG00000144895 PMC8584052__F2 P5C as an Interface of Proline Interconvertible Amino Acids and Its Role in Regulation of Cell Survival and Apoptosis ENSG00000136997 ENSG00000100033 PMC9452720__F1 How zoledronic acid improves osteoporosis by acting on osteoclasts ENSG00000175104 ENSG00000143387 PMC6349126__F1 Schematic outline of PC metabolism in yeast ENSG00000063660 ENSG00000173599 ENSG00000006007 PMC5701083__F2 Signaling pathways involving PFKFB3 ENSG00000180210 ENSG00000134982 ENSG00000138798 PMC4209037__F3 Gene association network (GAN) 3 in lung ENSG00000136603 ENSG00000183283 ENSG00000130159 ENSG00000118898 ENSG00000179163 PMC5701083__F3 Roles of PFKFB3 in different cancer cells ENSG00000185591 PMC2814429__F2 Regulation of autophagy and apoptosis ENSG00000152348 ENSG00000198793 ENSG00000144848 ENSG00000168040 ENSG00000145782 ENSG00000057663 PMC9356572__F2 Unique mutations in SARS-CoV-2 Omicron subvariants' non-spike proteins: Potential impacts on viral pathogenesis and host immune evasion ENSG00000088888 ENSG00000015285 ENSG00000154059 ENSG00000131323 ENSG00000276561 ENSG00000164342 PMC10881233__F2 Action of cryoablation combined with immune checkpoint blockers ENSG00000134982 PMC6706170__F1 AvB5 integrin/FAK-mediated phagocytic pathway in TM-1 cells ENSG00000144366 ENSG00000135218 ENSG00000198053 ENSG00000156299 PMC8514698__F2 Optimization of BCG Therapy Targeting Neutrophil Extracellular Traps, Autophagy, and miRNAs in Bladder Cancer: Implications for Personalized Medicine ENSG00000152348 ENSG00000126775 ENSG00000144848 ENSG00000005893 ENSG00000145782 ENSG00000057663 PMC7641543__F1 EMT transcription factors by Wnt/GSK3B/Beta-catenin/Snail and PI3K/AKT/GSK3B/Snail signaling ENSG00000134982 ENSG00000138798 ENSG00000169047 ENSG00000168036 ENSG00000146648 PMC10743660__F3 Nexus of Inflammation-Induced Epithelial-Mesenchymal Transition and Lung Cancer Progression: A Roadmap to Pentacyclic Triterpenoid-Based Therapies ENSG00000182718 ENSG00000019991 ENSG00000107562 ENSG00000291971 ENSG00000134982 ENSG00000168036 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000121966 ENSG00000140443 PMC11720236__F2 Mechanisms of exercise modulation of pulmonary fibrosis ENSG00000281324 ENSG00000168036 ENSG00000136869 PMC8168423__F9 Oral intake of Lactobacillus plantarum L‐14 extract alleviates TLR2‐ and AMPK‐mediated obesity‐associated disorders in high‐fat‐diet‐induced obese C57BL/6J mice ENSG00000172936 ENSG00000150455 ENSG00000026103 PMC10743660__F4 Immune component of inflammation-induced EMT in lung cancer ENSG00000108691 ENSG00000121807 ENSG00000168610 PMC11720236__F3 Exercise modulation of renal fibrosis ENSG00000086991 ENSG00000096717 PMC10743660__F6 Inhibition of inflammation-induced EMT by PTs ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000170558 ENSG00000168036 ENSG00000168610 ENSG00000145604 ENSG00000171992 ENSG00000100387 ENSG00000198742 ENSG00000163914 ENSG00000113558 ENSG00000189403 ENSG00000136869 ENSG00000172936 ENSG00000175104 ENSG00000146648 PMC11720236__F1 Pathogenesis of fibrosis: After tissue injury, immune cells (mainly macrophages) are activated and release cytokines (e ENSG00000168036 PMC10743660__F1 Key molecular events of EMT ENSG00000170558 ENSG00000168036 PMC11240630__F1 Pathways associated with the signaling of BCSCs ENSG00000134982 ENSG00000198793 ENSG00000128602 PMC11720236__F4 Exercise modulation of myocardial fibrosis ENSG00000118972 ENSG00000133048 ENSG00000163430 ENSG00000134013 ENSG00000105550 ENSG00000096717 ENSG00000142082 ENSG00000168610 PMC11720236__F5 Antifibrotic mechanisms of exercise: Exercise exerts its anti-fibrotic effects by directly or indirectly (secreting exerkines or targeting microRNAs) affecting multiple signaling pathways associated with fibrogenesis ENSG00000281324 ENSG00000133048 ENSG00000163430 ENSG00000105550 ENSG00000168036 ENSG00000096717 PMC9366252__F3 Progress of tumor-associated macrophages in the epithelial-mesenchymal transition of tumor ENSG00000134982 ENSG00000170558 ENSG00000198793 ENSG00000177606 ENSG00000168036 PMC10743660__F7 Inhibition of stemness by PTs ENSG00000145604 ENSG00000100387 ENSG00000134982 ENSG00000138798 ENSG00000113558 ENSG00000168036 ENSG00000168610 ENSG00000146648 PMC3318742__F8 Model of how RACK1 mediates activation of SHH/GLI signaling in NSCLC Cells ENSG00000164690 ENSG00000128602 PMC5605425__F1 Linking long non-coding RNA to control bile acid signaling and cholestatic liver fibrosis ENSG00000119888 ENSG00000167910 ENSG00000171791 ENSG00000267534 PMC6500875__F2 Annexin A1 in inflammation ENSG00000171049 PMC6500875__F3 Mechanisms of Annexin A1 in tumorigenesis PMC5884027__F2 NRF2- and SIRT1-signaling pathways targeted by antioxidant compounds ENSG00000096717 PMC6443714__F1 The cytoplasmic destruction complex constitutively targets Beta-catenin for degradation ENSG00000178860 ENSG00000162337 ENSG00000168036 PMC5872689__F6 Suggested mechanism of pinitol-induced effects on the insulin secretion pathway ENSG00000244731 ENSG00000084774 PMC5884027__F1 Schematics of the metabolic pathways and their cellular localization affected in branched-chain organic acidurias and homocystinuria disorders mentioned in this work ENSG00000119688 ENSG00000142273 ENSG00000110395 ENSG00000175198 ENSG00000137992 ENSG00000173599 ENSG00000114054 ENSG00000167775 ENSG00000124275 ENSG00000168288 ENSG00000103507 ENSG00000185339 ENSG00000091140 PMC1820632__F1 Cytokine-Effects on Glucocorticoid Receptor Function: Relevance to Glucocorticoid Resistance and the Pathophysiology and Treatment of Major Depression ENSG00000105397 ENSG00000115415 ENSG00000168610 PMC5827745__F2 BCR‐ABL pathway ENSG00000186716 ENSG00000198793 ENSG00000168036 ENSG00000128602 ENSG00000163501 PMC8112168__F1 Multiple catalytic functions of IPMK in inositol biosynthesis pathway ENSG00000168781 ENSG00000176095 ENSG00000151151 PMC7565564__F2 Examples of molecular mechanisms underlying the effects of uremic toxins on various cells, with focus on the aryl hydrocarbon receptor signaling (AHR) pathway ENSG00000291971 ENSG00000106546 PMC5187886__F2 Possible mechanisms of estrogen or EED action ENSG00000177606 ENSG00000185591 ENSG00000106459 PMC7773746__F1 Nuclear-Encoded lncRNA MALAT1 Epigenetically Controls Metabolic Reprogramming in HCC Cells through the Mitophagy Pathway ENSG00000171791 PMC6678879__F8 miR526b and miR655 overexpressing cells showing significant down regulation of tumour suppressor gene phosphatase and tensin homolog (PTEN) mRNA expression PMC5312548__F9 The role of NAD+ in the macrophage metabolic switch ENSG00000105835 ENSG00000096717 PMC6619438__F2 Innate immune recognition of Chlamydia ENSG00000174125 ENSG00000142627 ENSG00000164430 ENSG00000167207 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000106100 ENSG00000164342 PMC3127207__F4 GenMAPP Diagram of Cell Cycle Pathway Genes Regulated by Luteolin in E2-Treated MCF-7 Cells ENSG00000112576 ENSG00000101224 ENSG00000145386 ENSG00000118971 ENSG00000166851 ENSG00000134480 ENSG00000145604 ENSG00000094804 ENSG00000198176 ENSG00000134057 ENSG00000135446 ENSG00000132646 ENSG00000123374 ENSG00000105810 ENSG00000147082 ENSG00000139687 ENSG00000080839 ENSG00000175305 PMC7076373__F1 CDC1 DC development ENSG00000123685 ENSG00000140968 ENSG00000197992 ENSG00000173578 ENSG00000198178 PMC3127207__F2 Luteolin Effects on Estrogen Signaling Pathway (ESP) Genes ENSG00000171720 ENSG00000082175 ENSG00000291971 ENSG00000095321 ENSG00000142453 ENSG00000146678 ENSG00000108654 ENSG00000196498 ENSG00000155974 ENSG00000127616 ENSG00000141456 PMC6615902__F4 WNT signaling and regionalization of the GI tract epithelium ENSG00000165556 ENSG00000090402 ENSG00000131668 ENSG00000168036 ENSG00000163501 ENSG00000196628 PMC12043837__F4 Regulatory role of lactylation in glioma pathology ENSG00000184254 ENSG00000163884 PMC8582492__F1 Modes of Dysregulation of the Proto-Oncogene T-Cell Leukemia/Lymphoma 1A ENSG00000149311 ENSG00000138035 ENSG00000151490 ENSG00000291603 ENSG00000186716 ENSG00000177606 ENSG00000100721 PMC6912360__F8 Mechanism capable of expressing or inhibiting an effect of Temozolomide (TMZ) ENSG00000170430 ENSG00000095002 ENSG00000122512 PMC5941588__F9 Comparison of networks affected by FA or O3 exposure in females at different stages of the estrous cycle ENSG00000185215 ENSG00000151657 ENSG00000169857 ENSG00000172765 ENSG00000107443 ENSG00000136997 PMC10388730__F6 Influence of cold-stimulated adipocyte supernatant on the expression of adhesion-related molecules in Schwann cell line ENSG00000087095 ENSG00000170458 ENSG00000130522 ENSG00000138798 ENSG00000111837 ENSG00000121058 ENSG00000130159 ENSG00000099942 ENSG00000175104 ENSG00000127191 ENSG00000026103 PMC4978108__F2 Apoptosis in pancreatic Beta-islet cells in Type 2 diabetes ENSG00000002330 ENSG00000026103 PMC7738964__F3 Peroxisome proliferator-activated receptor (PPAR) signaling pathway in the MetaCore analysis ENSG00000157184 ENSG00000117054 ENSG00000087008 PMC7937674__F8 Schematic overview for the positive feedback loop between OTUD5 and mTOR signaling pathway ENSG00000198793 ENSG00000155792 ENSG00000292211 PMC6605495__F1 Nutrient flux through the HBP modulates protein O-GlcNAcylation ENSG00000147162 ENSG00000198408 PMC8441765__F8 Schematic illustration of the proposed mechanisms for paclitaxel-induced growth inhibition in PC9 cells ENSG00000188486 ENSG00000175054 ENSG00000138798 ENSG00000198793 ENSG00000123374 ENSG00000171791 ENSG00000168040 ENSG00000146648 PMC6605495__F2 Helper T cell differentiation and HBP ENSG00000115415 ENSG00000134982 ENSG00000107485 ENSG00000049768 ENSG00000168610 PMC5984665__F1 MicroRNA Regulation of K-Ras in Pancreatic Cancer and Opportunities for Therapeutic Intervention ENSG00000164056 ENSG00000166068 ENSG00000146648 ENSG00000196712 PMC9136457__F1 When PIP2 Meets p53: Nuclear Phosphoinositide Signaling in the DNA Damage Response ENSG00000148384 ENSG00000182621 ENSG00000151151 PMC7216198__F8 Regulatory role of the IPs in immune surveillance in PB CD34+ Cells of PMF JAK2V617F mutated patients ENSG00000224320 ENSG00000111537 ENSG00000115415 ENSG00000232326 ENSG00000273686 ENSG00000118520 ENSG00000174059 ENSG00000125347 PMC2797409__F3 Reconstructed CCM of S ENSG00000175066 ENSG00000127948 ENSG00000062485 PMC4347221__F1 Shifting ecologies of malignant and nonmalignant cells following BRAF inhibition ENSG00000157764 ENSG00000186716 PMC8036963__F3 DNA damage response (DDR) pathway involves sensor, transducer, mediator/amplifier, and effector proteins, which act following the induction of a DNA lesion or replication stress ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000164053 PMC4867368__F7 The mechanistically diverse PF03099 lipoyl metabolism enzymes ENSG00000107798 ENSG00000188992 ENSG00000198670 ENSG00000173239 PMC2579334__F3 Dysregulation of Mitochondrial Dynamics and the Muscle Transcriptome in ICU Patients Suffering from Sepsis Induced Multiple Organ Failure ENSG00000002330 ENSG00000095321 ENSG00000010810 ENSG00000106070 ENSG00000220205 PMC4637204__F4 Systemic Problems: A perspective on stem cell aging and rejuvenation ENSG00000170365 ENSG00000198793 ENSG00000168610 PMC4855646__F9 Signaling pathways of TRIAD ENSG00000122566 ENSG00000197386 ENSG00000166851 ENSG00000197451 PMC8236053__F2 Comparative Review of the Cell Biology, Biochemistry, and Genetics of Lactose Synthesis ENSG00000112977 ENSG00000069482 PMC6927352__F5 Comparative RNA-sequencing profiled the differential gene expression of liver in response to acetyl-CoA carboxylase inhibitor GS-0976 in a mouse model of NASH ENSG00000136457 ENSG00000135218 ENSG00000169896 ENSG00000110799 ENSG00000026508 ENSG00000010278 ENSG00000135605 ENSG00000154096 PMC8616064__F2 Mesothelioma Malignancy and the Microenvironment: Molecular Mechanisms ENSG00000019991 ENSG00000108691 ENSG00000089692 PMC5131002__F2 YAP mediated gene expression in liver fibrosis ENSG00000126016 ENSG00000163914 ENSG00000131023 ENSG00000291442 PMC8431187__F2 Myeloma–Bone Interaction: A Vicious Cycle via TAK1–PIM2 Signaling ENSG00000162692 ENSG00000168610 ENSG00000292210 PMC4336165__F2 Growing recognition of the role for rare missense substitutions in breast cancer susceptibility ENSG00000149311 ENSG00000012048 ENSG00000136492 ENSG00000083093 ENSG00000051180 ENSG00000139618 ENSG00000183765 PMC7699596__F3 Key autophagy pathway and its regulators (natural compounds) for treating diverse cancers ENSG00000177169 ENSG00000198793 PMC6636509__F8 Proposed model for the impact of targeted therapeutics, vemurafenib (PLX) and trametinib (TRA) on differentiated/pigmented phenotype of melanoma cells ENSG00000080166 PMC5618570__F2 Glycans and insulin/IGF system in cancer: an integrated mechanism ENSG00000147162 ENSG00000146678 ENSG00000128268 ENSG00000140443 PMC6027367__F1 Unfolded protein response and NFKB signaling ENSG00000128272 ENSG00000144895 ENSG00000162772 ENSG00000127191 PMC5618570__F1 Insulin/insulin-like growth factor (IGF) system ENSG00000197081 ENSG00000140443 PMC4412144__F3 IPA Network ENSG00000177971 ENSG00000070495 ENSG00000072274 ENSG00000060237 ENSG00000076706 ENSG00000161955 ENSG00000175895 ENSG00000163141 ENSG00000180957 ENSG00000118515 ENSG00000157514 ENSG00000095794 ENSG00000189067 PMC9388724__F5 Neuronal ferroptosis after intracerebral hemorrhage ENSG00000151012 ENSG00000102226 ENSG00000167468 ENSG00000127528 PMC4245781__F1 Signaling pathways of TRKA activation by NGF ENSG00000169047 PMC10705282__F4 In PTC, glycolysis is crucial for tumor growth ENSG00000168610 PMC6194107__F2 Origins of centromeric breaks ENSG00000175054 ENSG00000080345 ENSG00000198887 ENSG00000113318 ENSG00000088305 ENSG00000057468 ENSG00000131747 ENSG00000197299 ENSG00000051180 ENSG00000095002 PMC11375557__F2 Transcription Factors and Signaling Pathways in the Process of EMT ENSG00000169554 ENSG00000141448 ENSG00000138798 ENSG00000115221 ENSG00000168610 ENSG00000086548 ENSG00000145113 ENSG00000136826 ENSG00000159167 ENSG00000176692 ENSG00000125398 ENSG00000157227 ENSG00000188042 ENSG00000112984 ENSG00000145741 ENSG00000163993 ENSG00000163577 ENSG00000125850 ENSG00000185591 PMC3757712__F3 Crosstalk between the Nrf2 and NFKB pathways ENSG00000171720 ENSG00000178573 ENSG00000079999 PMC10705282__F2 Exogenous pathway is a process for delivering triglycerides to peripheral tissues using chylomicrons and VLDLs ENSG00000130164 PMC2758290__F1 The SIAE (sialic acid acetylesterase)-Siglec pathway for inhibitory signaling ENSG00000186716 ENSG00000110013 PMC3678537__F2 Wound Healing in Development ENSG00000134982 ENSG00000168036 PMC3622313__F1 Regulation of HDL homeostasis by miRNAs ENSG00000130164 ENSG00000042832 ENSG00000073734 ENSG00000160179 ENSG00000081923 PMC4052099__F1 Predicted insulin signaling pathway in schistosomes based on the characterization of schistosome insulin receptors, the published S ENSG00000110395 ENSG00000150907 ENSG00000198793 PMC8602684__F2 Metallothionein 1: A New Spotlight on Inflammatory Diseases ENSG00000115415 ENSG00000100985 ENSG00000168610 PMC11585094__F7 Potential ferroptosis and osteoporosis biomarkers through TMT proteomics and bioinformatics analysis ENSG00000168003 ENSG00000151012 ENSG00000181019 ENSG00000167468 ENSG00000079999 PMC11375557__F1 Mechanisms of Epithelial-Mesenchymal Transition ENSG00000138798 ENSG00000170558 PMC11697870__F5 Multifaceted biological processes and pathways that are identified to be associated with AD progression ENSG00000278316 ENSG00000186716 PMC5375109__F1 miR-33 regulation of adaptive fibrotic response in cardiac remodeling ENSG00000135446 ENSG00000113360 PMC1172066__F8 Model depicting how inner ear polarity is generated in response to extracellular signals ENSG00000075891 ENSG00000164690 ENSG00000168505 PMC4201594__F6A FOXO3-mTOR Metabolic Cooperation in the Regulation of Erythroid Cell Maturation and Homeostasis PMC3746754__F2 Iron metabolism in the eye, a review ENSG00000010704 ENSG00000106327 PMC8640549__F3 GPR56/ADGRG1 in health and disease ENSG00000163914 ENSG00000110651 PMC4613459__F2 Repurposing metformin: an old drug with new tricks in its binding pockets ENSG00000168610 ENSG00000140443 PMC4823983__F5 Interaction between the genes differentially expressed in response to HDM ENSG00000179934 ENSG00000134460 ENSG00000102962 ENSG00000137033 ENSG00000109321 ENSG00000183625 ENSG00000166090 ENSG00000049768 ENSG00000277943 ENSG00000186827 ENSG00000150782 ENSG00000108691 ENSG00000102970 ENSG00000112115 ENSG00000186652 ENSG00000121053 ENSG00000106178 PMC8635240__F8 VDR Signaling via the Enzyme NAT2 Inhibits Colorectal Cancer Progression ENSG00000168610 PMC2859139__F1 Immunoregulatory pathways ENSG00000111537 ENSG00000105329 PMC3017908__F6 Major pathways affected in NMSC ENSG00000164161 ENSG00000141480 ENSG00000164690 PMC136456__F7 The modulation of cellular signaling pathways by NS5A ENSG00000002330 PMC8606660__F6 Intrinsic Mechanical Cues and Their Impact on Stem Cells and Embryogenesis ENSG00000186575 ENSG00000114978 ENSG00000150457 ENSG00000131023 PMC6072898__F3 Mechanistic aspects of the antioxidant and anti-inflammatory action of berberine ENSG00000163914 ENSG00000175567 ENSG00000096717 PMC6537107__F3 Changes in PUFA metabolomes are conserved across pharmacological and physiological models of skeletal muscle injury ENSG00000226275 PMC6008965__F2 5-Fluorouracil drug pathway demonstrating the interaction of multiple gene products ENSG00000128951 ENSG00000136877 ENSG00000171848 ENSG00000143839 ENSG00000147647 ENSG00000137563 PMC8469789__F3 Ubiquitin-Specific Proteases: Players in Cancer Cellular Processes ENSG00000122025 ENSG00000144554 ENSG00000132646 ENSG00000026103 PMC9379326__F2 Fucoxanthin: A Promising Phytochemical on Diverse Pharmacological Targets ENSG00000167910 ENSG00000161533 ENSG00000026103 PMC8568546__F3 RNA Methylation in Regulating Stem Cell Fate and Function-Focus on m6A ENSG00000149658 ENSG00000198492 ENSG00000156574 ENSG00000165819 PMC8568546__F1 RNA Methylation in Regulating Stem Cell Fate and Function-Focus on m6A ENSG00000145388 ENSG00000156574 ENSG00000146457 ENSG00000165819 PMC9600852__F1 Molecular Defense Response of Pine Trees (Pinus spp.) to the Parasitic Nematode Bursaphelenchus xylophilus PMC8877616__F1 Current and Emerging Medical Therapies in Pituitary Tumors ENSG00000198793 ENSG00000146648 ENSG00000149295 PMC9149431__F3 All About (NK Cell-Mediated) Death in Two Acts and an Unexpected Encore: Initiation, Execution and Activation of Adaptive Immunity ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000026103 PMC5649110__F1 Narni-Mancinelli et al ENSG00000291603 ENSG00000111537 ENSG00000122877 ENSG00000103257 ENSG00000143184 PMC9188247__F8 Intramyocardial injected human umbilical cord-derived mesenchymal stem cells (HucMSCs) contribute to the recovery of cardiac function and the migration of CD4+ T cells into the infarcted heart via CCL5/CCR5 signaling ENSG00000108691 ENSG00000121807 PMC4967210__F13 Schematic summary of novel TXNIP-NFYA-SREBP2/miR-33a-AMPKA/CROT/CPT1/HADHB signaling pathway conferring TXNIP regulation of myocardial fatty acid oxidation ENSG00000001167 ENSG00000138029 ENSG00000265972 ENSG00000005469 PMC6579706__F1 Unfolded protein response (UPR) ENSG00000144895 ENSG00000100219 PMC2722767__F3 Application of SysPTM tools ENSG00000087095 ENSG00000134982 ENSG00000147869 ENSG00000168036 ENSG00000115718 PMC11670700__F1 Inhibition of the canonical Wnt/Beta-catenin signaling pathway by BI 905677 ENSG00000281324 ENSG00000162337 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000196628 PMC4022110__F1 Schematic overview of MBL-dependent activation of the lectin pathway of complement ENSG00000039537 ENSG00000244731 ENSG00000166278 ENSG00000236625 PMC9204405__F1 Sonic hedgehog pathway for the treatment of inflammatory diseases: implications and opportunities for future research ENSG00000108691 ENSG00000121807 ENSG00000168610 PMC4441295__F5 Fangchinoline inhibits the growth and invasive potential of gastric cancer cells by inhibiting the PI3K/Akt pathway ENSG00000087245 ENSG00000123374 ENSG00000100985 PMC3672943__F1 Integration of Cell Signalling Pathways into Higher Order Networks Sculpts Transcriptional Landscapes ENSG00000160973 ENSG00000168036 ENSG00000089225 PMC3635745__F1 Autoimmunity risk alleles: hotspots in B cell regulatory signaling pathways ENSG00000177455 ENSG00000007312 ENSG00000010810 ENSG00000153064 ENSG00000110651 ENSG00000010671 PMC10888650__F1 Potassium’s (K+) Role in Various Cellular Processes ENSG00000169047 ENSG00000177606 ENSG00000168040 ENSG00000064012 ENSG00000164305 ENSG00000140443 ENSG00000084774 ENSG00000026103 PMC10888650__F4 ABCC8 Expression in Hypoxic and Inflammatory Conditions ENSG00000006071 ENSG00000172936 ENSG00000185591 ENSG00000127191 PMC6819784__F2 Macrophage infection affects host metabolic state and can induce an M1 profile ENSG00000180210 ENSG00000111537 ENSG00000027697 ENSG00000136869 ENSG00000175567 PMC3427885__F4 Impact of HCV infection on ILK signaling ENSG00000198793 ENSG00000187266 ENSG00000185010 PMC12129893__F2 Sources of the microbiota and mechanisms by which bacteria regulate tumor progression ENSG00000168036 ENSG00000136869 PMC3925803__F5 Model showing elevated calcium and/or phosphate up-regulate HGF secretion and c-Met activation in conjunction with activation of the PI3K/Akt signalling pathway, leading to SMC mineralisation, which can be inhibited by AdNK4 treatment ENSG00000019991 ENSG00000074181 PMC8745708__F4 Neurofibromatosis Type 1 Gene Alterations Define Specific Features of a Subset of Glioblastomas ENSG00000198793 ENSG00000175592 ENSG00000196712 PMC5129910__F8 Environmental tobacco smoke increases autophagic effects but decreases longevity associated with Sirt-1 protein expression in young C57BL mice hearts ENSG00000197081 ENSG00000096717 ENSG00000140443 PMC7945682__F2 Summary of targets to generate Super-Treg ENSG00000094631 ENSG00000228716 ENSG00000134460 ENSG00000124422 ENSG00000198793 ENSG00000198589 ENSG00000273686 ENSG00000049768 ENSG00000106546 ENSG00000100385 ENSG00000111537 ENSG00000159216 ENSG00000048052 ENSG00000163517 ENSG00000026103 PMC4538424__F1 MicroRNAs as major players in immune-mediated beta-cell damage in autoimmune diabetes ENSG00000220205 ENSG00000184216 PMC8660617__F10 Prognostic and immune infiltration signatures of proteasome 26S subunit, non-ATPase (PSMD) family genes in breast cancer patients ENSG00000149311 ENSG00000175054 ENSG00000125817 ENSG00000115163 ENSG00000117697 ENSG00000134982 ENSG00000117399 ENSG00000104368 ENSG00000149503 PMC8660617__F11 Prognostic and immune infiltration signatures of proteasome 26S subunit, non-ATPase (PSMD) family genes in breast cancer patients ENSG00000149311 ENSG00000175054 ENSG00000134982 ENSG00000146648 ENSG00000117399 ENSG00000132341 PMC8660617__F12 Prognostic and immune infiltration signatures of proteasome 26S subunit, non-ATPase (PSMD) family genes in breast cancer patients ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000134982 ENSG00000135446 ENSG00000142453 ENSG00000205250 ENSG00000105810 ENSG00000079999 ENSG00000132341 PMC8660617__F13 Prognostic and immune infiltration signatures of proteasome 26S subunit, non-ATPase (PSMD) family genes in breast cancer patients ENSG00000149311 ENSG00000175054 ENSG00000159224 ENSG00000137033 ENSG00000186716 ENSG00000163914 ENSG00000173599 ENSG00000005893 ENSG00000100219 PMC3539736__F3 PI3K Signaling in B and T Lymphocytes: New Developments and Therapeutic Advances ENSG00000127528 ENSG00000049768 ENSG00000112486 PMC8660617__F14 Prognostic and immune infiltration signatures of proteasome 26S subunit, non-ATPase (PSMD) family genes in breast cancer patients ENSG00000149311 ENSG00000175054 ENSG00000090402 ENSG00000144554 ENSG00000134982 ENSG00000128602 PMC8660617__F15 Prognostic and immune infiltration signatures of proteasome 26S subunit, non-ATPase (PSMD) family genes in breast cancer patients ENSG00000149311 ENSG00000175054 ENSG00000134982 ENSG00000188130 ENSG00000132341 PMC8630697__F3 Function of cGAS-STING Pathway in Treatment of Pancreatic Cancer ENSG00000116688 ENSG00000167468 ENSG00000171109 PMC9536535__F7 Proposed model of S100A8/9 induction ENSG00000170890 ENSG00000143546 ENSG00000160013 ENSG00000197272 ENSG00000136869 ENSG00000105246 ENSG00000168610 PMC6813793__F3 Cross talk of Na+ and Ca2+signalling between the cell membrane and the mitochondria.Influx of Ca2+ into cells is mediated by multiple cell membrane pathways ENSG00000107745 ENSG00000156026 ENSG00000137672 ENSG00000196689 PMC9225892__F8 Vericiguat Modulates Osteoclast Differentiation and Bone Resorption via a Balance between VASP and NFKB Pathways ENSG00000143387 PMC3690520__F3 TCR signaling pathway leading to NFKB and JNK activation ENSG00000134982 PMC1160519__F6 Cardiac glycosides inhibit TNFA/NFKB signaling by blocking recruitment of TRADD to the TNFR ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC6111343__F7 MiR-146a-5p in the Toll-like receptor signaling pathway ENSG00000239732 ENSG00000145839 ENSG00000144410 ENSG00000170458 ENSG00000136869 ENSG00000131323 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000164342 ENSG00000143387 PMC6050918__F8 Proposed model for CaSR activation of NCC through a PKC-WNK4-SPAK pathway ENSG00000105656 ENSG00000080166 ENSG00000146021 PMC8807488__F3 Emerging Landscape of Long Non-Coding RNAs in Wilms Tumor ENSG00000118971 ENSG00000128191 PMC8807488__F4 Emerging Landscape of Long Non-Coding RNAs in Wilms Tumor ENSG00000104856 ENSG00000106571 PMC6468893__F10 Dual prey-inactivation strategy of the venom of C ENSG00000135253 PMC5397035__F12 Lack of BTK does not impair monocytes and polymorphonuclear cells functions in X-linked agammaglobulinemia under treatment with intravenous immunoglobulin replacement ENSG00000149269 ENSG00000010671 PMC7207242__F1 Complement activation pathways and viral evasion of the complement cascade ENSG00000113600 ENSG00000196352 ENSG00000165280 ENSG00000244731 ENSG00000166278 PMC6361575__F3 Smad3 linker phosphorylation negatively regulates transforming growth factor‐B (TGF‐B)/Smad3 signaling ENSG00000019991 ENSG00000176692 ENSG00000138795 ENSG00000138798 ENSG00000168036 ENSG00000185591 PMC4929323__F2 Microenvironmental regulation of oligodendrocyte replacement and remyelination in spinal cord injury ENSG00000065361 ENSG00000198793 ENSG00000163914 ENSG00000128342 ENSG00000168610 ENSG00000178568 PMC12035889__F4 Mechanism of trained immunity and related research ENSG00000167207 ENSG00000198793 ENSG00000136869 ENSG00000140443 PMC7402325__F3 An ambivalence model of PI3K/AKT/SOX2 signaling and DNA damage control in various stem cell conditions ENSG00000002330 ENSG00000123374 PMC2867412__F2 Proposed role for AMPK in the kidney in coupling catabolic pathways requiring ATP hydrolysis (primarily sodium transport) with metabolic pathways leading to ATP synthesis (primarily fatty acid and glucose oxidation) ENSG00000198793 ENSG00000167658 ENSG00000001626 PMC12035889__F2 Signaling pathways inflammation and oxidative stress induced by LPS, HIS, iE-DAP and MDP ENSG00000167207 ENSG00000170458 ENSG00000198793 ENSG00000136869 ENSG00000106100 PMC8326121__F6 Multifaceted Role of Long Non-Coding RNA in Gastric Cancer: Current Status and Future Perspectives ENSG00000134982 ENSG00000146648 PMC7402325__F1 The canonical PI3K/AKT pathway with indication of key stimuli and central output functions ENSG00000002330 ENSG00000163235 ENSG00000123374 ENSG00000159399 PMC7402325__F2 PI3K/AKT pathway is a superordinate module of SOX2 and p53 expression control PMC8326121__F1 Multifaceted Role of Long Non-Coding RNA in Gastric Cancer: Current Status and Future Perspectives ENSG00000051180 PMC7796211__F1 P53 network and metabolism ENSG00000168283 ENSG00000167967 ENSG00000198625 PMC7796211__F2 BMI1, ARF, MDM2, MDM4, E4F1, and p53 proteins shuttle between different subcellular compartments where they control different metabolic functions ENSG00000168283 ENSG00000128272 ENSG00000167967 ENSG00000198625 PMC8156237__F4 Do Autism Spectrum and Autoimmune Disorders Share Predisposition Gene Signature Due to mTOR Signaling Pathway Controlling Expression? ENSG00000051523 ENSG00000033327 ENSG00000140262 ENSG00000100906 ENSG00000109320 ENSG00000198793 ENSG00000169047 ENSG00000095015 ENSG00000232326 ENSG00000126883 ENSG00000112715 ENSG00000132693 ENSG00000161955 ENSG00000159216 ENSG00000213658 ENSG00000170458 ENSG00000145321 ENSG00000119912 PMC7796211__F3 Several metabolic pathways in which the different components of the p53 network are implicated, including glycolysis, Oxphos, amino acid, and fatty acid metabolism ENSG00000168283 ENSG00000167967 ENSG00000198625 PMC9075007__F8 Working model for the effect of SULF2 monoclonal antibody 5D5 on PDGFRBeta-YAP signaling in CCA ENSG00000196562 PMC3916405__F1 Distinct Antiviral Responses in Pluripotent versus Differentiated Cells ENSG00000088888 ENSG00000135828 ENSG00000164342 PMC3950678__F6 Causal gene network inferred from top discriminative modules at a significance level of 0.005 ENSG00000128655 ENSG00000106436 ENSG00000163738 ENSG00000145020 ENSG00000178445 ENSG00000106631 ENSG00000132170 ENSG00000284320 ENSG00000163558 ENSG00000137992 ENSG00000172482 ENSG00000146701 ENSG00000091140 ENSG00000148377 ENSG00000167701 PMC9934381__F11 Model of cGAS-mediated antiviral function in EV-A71, SVV, and FMDV replication ENSG00000183735 ENSG00000164430 PMC3579782__F6 Early Activation of Rat Skeletal Muscle IL-6/STAT1/STAT3 Dependent Gene Expression in Resistance Exercise Linked to Hypertrophy ENSG00000009709 ENSG00000111049 ENSG00000115415 ENSG00000113520 ENSG00000168610 PMC6487091__F3 Mechanisms involved in the prooncogenic activation of the NRF2/KEAP1 pathway ENSG00000157764 ENSG00000177606 ENSG00000136997 ENSG00000079999 PMC4869873__F4 Schematics of the inside-out signaling of integrin activation ENSG00000149782 ENSG00000186111 ENSG00000105639 ENSG00000137841 ENSG00000010671 ENSG00000105723 ENSG00000141968 PMC4436788__F12 Proposed model of arachidonoyl-CoA shunting in LPCAT3-deficient mice ENSG00000042832 ENSG00000173599 ENSG00000111684 ENSG00000198670 PMC7940512__F1 BM-resident CD69+regulatory T cells (CD69+ Treg) decrease expression of CD39 which is required for the canonical CD39/CD73 adenosine pathway ENSG00000089692 ENSG00000181847 ENSG00000173599 PMC6719876__F3 Analysis of potential roles of combinatorial microRNA regulation in occurrence of valvular heart disease with atrial fibrillation based on computational evidences ENSG00000087095 ENSG00000117020 ENSG00000177189 ENSG00000011566 ENSG00000172380 ENSG00000101109 ENSG00000149930 ENSG00000075461 ENSG00000130522 ENSG00000168067 ENSG00000284953 ENSG00000099942 PMC6719876__F4 Analysis of potential roles of combinatorial microRNA regulation in occurrence of valvular heart disease with atrial fibrillation based on computational evidences ENSG00000087095 ENSG00000166167 ENSG00000163251 ENSG00000154001 ENSG00000174804 ENSG00000175592 ENSG00000072803 ENSG00000118971 ENSG00000145349 ENSG00000101333 PMC2729995__F1 Apoptosis and the main anti-apoptotic molecules: Binding of death receptors (Fas, TNF-R, TRAIL-R) to their ligands (Fas-L, TNF, TRAIL) initiates the extrinsic apoptotic pathway ENSG00000102871 ENSG00000171791 ENSG00000168040 PMC7196481__F3 Expression profiling of winged and wingless destined pea aphid embryos implicates insulin/insulin growth factor signaling in morph differences ENSG00000087095 ENSG00000166349 ENSG00000171105 ENSG00000138798 ENSG00000127528 ENSG00000175097 ENSG00000145604 ENSG00000149311 ENSG00000138764 ENSG00000123374 ENSG00000145782 ENSG00000176165 ENSG00000146648 ENSG00000168685 PMC11311808__F2 Genetic and Signalling pathway dysregulation in AC ENSG00000186575 ENSG00000134982 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC9541233__F1 Are UMFA (un‐metabolized folic acid) and endocrine disruptor chemicals (EDCs) co‐responsible for sperm degradation? An epigenetic/methylation perspective ENSG00000228716 ENSG00000173638 ENSG00000076351 PMC3376184__F3 Function network built upon genes selected from the identified genetic component ENSG00000074211 ENSG00000148680 ENSG00000131323 ENSG00000038002 ENSG00000145349 ENSG00000178568 ENSG00000182256 PMC5861586__F2 Biological pathways whereby PM2.5 promotes cardiovascular events ENSG00000163914 ENSG00000198576 ENSG00000136869 PMC3517092__F1 Schematic depiction of the role of the retromer complex in mediating endosomal protein sorting ENSG00000112335 ENSG00000143376 ENSG00000111237 ENSG00000069329 PMC9503294__F2 Roles of Skin Langerhans Cells in Immune Tolerance and Cancer Immunity ENSG00000116031 ENSG00000134757 ENSG00000168610 ENSG00000106546 PMC7219856__F1 Interactions between the renin–angiotensin–aldosterone system and coronavirus Disease-2019 ENSG00000130234 ENSG00000184012 PMC4177847__F4 Comparative Transcriptome Analysis Reveals the Genetic Basis of Skin Color Variation in Common Carp ENSG00000066468 ENSG00000120057 ENSG00000101440 ENSG00000111186 ENSG00000080166 ENSG00000107165 PMC7167370__F8 Possible mechanism of miR-519d overexpression in HCC ENSG00000198793 ENSG00000084733 ENSG00000057663 PMC11724471__F1 KRAS proteins and metabolic pathways affected by oncogenic KRAS mutation ENSG00000125166 ENSG00000131473 ENSG00000135218 ENSG00000134824 ENSG00000149485 ENSG00000198793 ENSG00000169710 ENSG00000159399 PMC7398104__F5 TGFB1 pathway activation is reduced following RYGB ENSG00000150782 ENSG00000105329 ENSG00000164400 ENSG00000180875 ENSG00000106546 ENSG00000172201 PMC5801739__F2 Aberrant mTOR Signaling and Disrupted Autophagy: the Missing Link in Potential Vigabatrin-Associated Ocular Toxicity? ENSG00000113262 ENSG00000291363 ENSG00000102287 ENSG00000166501 ENSG00000168036 ENSG00000167965 ENSG00000112715 ENSG00000168610 ENSG00000230034 PMC8396471__F2 Fibrotic Idiopathic Interstitial Lung Disease: The Molecular and Cellular Key Players ENSG00000177575 ENSG00000110711 ENSG00000137673 ENSG00000168036 ENSG00000164690 PMC6904873__F6 PGP-mediated metabolite repair maintains flux through glycolysis and the pentose phosphate pathway ENSG00000184207 PMC5214458__F1 Schematic demonstrating the signaling networks and their cross talks involved in differentiating the mesenchymal stem cells (MSCs) into osteoblasts ENSG00000178860 ENSG00000281324 ENSG00000162337 ENSG00000163914 ENSG00000168036 PMC9649847__F1 Tight Junctions, the Epithelial Barrier, and Toll-like Receptor-4 During Lung Injury ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC10419152__F1 MAPK signaling pathways in mammalian cells: The MAPK signaling pathways are mediated by highly conserved MAPKs, which are activated sequentially ENSG00000174125 ENSG00000172680 ENSG00000070831 ENSG00000291971 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC10419152__F2 Mammalian MAPK pathways by effector proteins: This figure depicts the various components of MAPK pathways targeted by the bacterial effector proteins ENSG00000070831 ENSG00000163914 ENSG00000175104 PMC8547127__F1 Tipping the balance: intricate roles of the complement system in disease and therapy ENSG00000039537 ENSG00000063015 ENSG00000113600 ENSG00000134830 ENSG00000291559 ENSG00000288512 ENSG00000203710 ENSG00000196352 ENSG00000244731 ENSG00000166278 ENSG00000182326 ENSG00000236625 PMC8534108__F1 Metabolomic Profiling in Renal Cell Carcinoma Patients: News and Views ENSG00000198793 ENSG00000171791 PMC3785124__F7 Simplified network controlling the fate decisions between osteogenic and adipogenic lineages in huAFMSCs ENSG00000134982 PMC8052156__F6 Active ingredient-target-pathway network ENSG00000068976 ENSG00000149968 ENSG00000128052 ENSG00000113161 ENSG00000123374 ENSG00000105810 ENSG00000100504 ENSG00000001626 ENSG00000096717 ENSG00000073756 ENSG00000140443 ENSG00000132170 PMC5292790__F1 Immune response in the polar clinical forms of leprosy ENSG00000177575 ENSG00000130164 ENSG00000239998 ENSG00000090659 PMC3769370__F8 Radioactive 125I Seed Inhibits the Cell Growth, Migration, and Invasion of Nasopharyngeal Carcinoma by Triggering DNA Damage and Inactivating VEGF-A/ERK Signaling ENSG00000149311 ENSG00000175054 ENSG00000134057 ENSG00000112715 PMC7795223__F1 Transcriptional AHR Signaling Pathway ENSG00000110711 ENSG00000291971 ENSG00000106546 PMC7447759__F8 Functional annotation network ENSG00000143549 ENSG00000185022 ENSG00000055163 ENSG00000022267 ENSG00000162772 ENSG00000186469 PMC12028195__F1 DNA damage response (DDR) signaling pathway and DDR inhibitors used in clinical settings ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000083093 ENSG00000051180 ENSG00000140464 ENSG00000139618 PMC7745059__F1 Small molecules targeting the innate immune cGAS‒STING‒TBK1 signaling pathway ENSG00000183735 ENSG00000164430 ENSG00000197594 PMC6280669__F2 Proposed TLR signaling network modified from previous reports (; ; ) ENSG00000174125 ENSG00000170458 ENSG00000125538 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC3223826__F5 JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors ENSG00000187608 ENSG00000160563 ENSG00000148702 ENSG00000026508 ENSG00000124212 PMC12047224__F4 NFKB activation via the IKB degradation route is a common mechanism ENSG00000137275 ENSG00000102871 ENSG00000082512 ENSG00000172936 ENSG00000157625 ENSG00000083799 ENSG00000154124 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC9179338__F3 Small but Powerful: The Human Vault RNAs as Multifaceted Modulators of Pro-Survival Characteristics and Tumorigenesis ENSG00000284099 ENSG00000112561 PMC11988131__F3 Dual function of PHLDA3 as both an apoptosis inducer and inhibitor ENSG00000174307 ENSG00000271303 ENSG00000100219 PMC3221733__F3 Drosophila melanogaster as a model system for human brain cancers ENSG00000135446 ENSG00000136997 ENSG00000164327 ENSG00000123374 ENSG00000146648 PMC7401772__F6 Hypothetical scheme of the regulatory network underlying miR-19b targeted TSLP ENSG00000113520 ENSG00000145777 PMC6397564__F6 Critical roles of B3GalT5 and the globo-series GSLs in regulating the apoptosis and survival of breast carcinoma cells ENSG00000026508 ENSG00000168036 ENSG00000183778 ENSG00000168040 ENSG00000146648 ENSG00000164305 ENSG00000026103 PMC3959190__F3 Metabolome-based genome-wide association study of maize kernel leads to novel biochemical insights ENSG00000047410 ENSG00000172005 PMC9634082__F2 Ubiquitin modification in osteogenic differentiation and bone formation: From mechanisms to clinical significance ENSG00000132109 ENSG00000036672 ENSG00000173039 ENSG00000168036 ENSG00000117399 ENSG00000076604 ENSG00000115464 ENSG00000145604 ENSG00000066468 ENSG00000170365 ENSG00000069869 ENSG00000110395 ENSG00000163251 ENSG00000078747 ENSG00000198742 ENSG00000115266 ENSG00000138942 ENSG00000175104 ENSG00000134588 ENSG00000277276 ENSG00000221926 PMC9592993__F6 Integrating network pharmacology and experimental verification to decipher the immunomodulatory effect of Bu-Zhong-Yi-Qi-Tang against poly (I:C)-induced pulmonary inflammation ENSG00000157404 ENSG00000291971 ENSG00000198793 ENSG00000112715 ENSG00000122194 ENSG00000121966 ENSG00000106546 ENSG00000180210 ENSG00000122025 ENSG00000117525 ENSG00000239732 ENSG00000082175 ENSG00000149968 ENSG00000128052 ENSG00000136997 ENSG00000123374 ENSG00000136869 ENSG00000023445 ENSG00000104365 ENSG00000086991 ENSG00000269335 ENSG00000173039 ENSG00000089041 ENSG00000007908 ENSG00000170425 ENSG00000073756 ENSG00000168610 ENSG00000117322 ENSG00000132170 ENSG00000224320 ENSG00000120899 ENSG00000163131 ENSG00000134853 ENSG00000100985 ENSG00000146648 PMC6413120__F1 The MRN complex and the DNA-damage response ENSG00000143799 ENSG00000149311 ENSG00000012048 PMC4695904__F2 Oncogenic miRNAs involved in the apoptotic pathway ENSG00000122966 ENSG00000104081 PMC10135105__F3 Activation of NRF2 signaling pathway by 4-HNE ENSG00000178573 ENSG00000079999 PMC9145654__F5 TGFBeta-Treated Placenta-Derived Mesenchymal Stem Cells Selectively Promote Anti-Adipogenesis in Thyroid-Associated Ophthalmopathy ENSG00000113161 PMC4773776__F4 PKD2 and PKD3 support EMT and cell migration ENSG00000130669 PMC3166203__F10 Different ways to activate NFKB ENSG00000104856 ENSG00000102871 ENSG00000082512 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC6014919__F1 KRAS Activating Signaling Triggers Arteriovenous Malformations ENSG00000198793 ENSG00000121879 PMC5187938__F1 Proposed model of the role of KDM6A/B in definitive endoderm differentiation ENSG00000168036 ENSG00000132510 ENSG00000277641 PMC3166203__F12 Upstream kinases and redox-sensitive phosphatases in NFKB activation ENSG00000124102 PMC3166203__F13 Redoxosome formation in IL-1 signaling ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC7000593__F6 Role and pathway acquired by keratin, cytokines, and interleukins in horn SCC ENSG00000115415 ENSG00000175104 PMC4628872__F1 The canonical and noncanonical regulatory pathways of Nrf2 signaling ENSG00000178573 ENSG00000023909 ENSG00000057663 ENSG00000079999 PMC6311434__F7 Schematic molecular mechanism of SHH pathway regulation by HER2 in breast cancer cells ENSG00000164690 PMC8630697__F1 Function of cGAS-STING Pathway in Treatment of Pancreatic Cancer ENSG00000183735 ENSG00000213928 ENSG00000164430 ENSG00000115415 ENSG00000142166 PMC4028786__F1 Homocysteine metabolic pathways PMC3356707__F1 Canonical WNT signaling pathway ENSG00000087095 ENSG00000281324 ENSG00000164736 ENSG00000162337 ENSG00000134982 ENSG00000147869 ENSG00000173218 ENSG00000168036 ENSG00000100888 PMC8802512__F2 The S100 protein family in rheumatoid arthritis ENSG00000150455 PMC11935715__F7 Piezo1 promotes atherosclerotic endothelial inflammation in response to OSS ENSG00000291971 ENSG00000162692 ENSG00000103335 PMC12229362__F3 Phosphoinositide compartment ENSG00000143147 ENSG00000148384 PMC4807419__F1 The transcriptional and posttranscriptional regulation of LDLR expression ENSG00000130164 ENSG00000169174 PMC2766052__F8 The E3 Ubiquitin Ligase Triad3A Negatively Regulates the RIG-I/MAVS Signaling Pathway by Targeting TRAF3 for Degradation ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000276561 PMC8358777__F7 Exploring the Pharmacological Mechanism of Radix Salvia Miltiorrhizae in the Treatment of Radiation Pneumonia by Using Network Pharmacology ENSG00000177455 ENSG00000103479 ENSG00000142192 ENSG00000065833 ENSG00000002330 ENSG00000069482 ENSG00000111837 ENSG00000168040 PMC8265131__F8 Metabolomic and transcriptomic profiling of adult mice and larval zebrafish leptin mutants reveal a common pattern of changes in metabolites and signaling pathways ENSG00000182718 ENSG00000197043 ENSG00000283887 ENSG00000151726 ENSG00000196975 ENSG00000138772 ENSG00000124212 ENSG00000073756 ENSG00000127472 ENSG00000079999 ENSG00000184381 ENSG00000243708 ENSG00000095303 ENSG00000275565 ENSG00000123983 PMC6465568__F2 Signal crosstalk in NFKB transcriptional regulation ENSG00000171855 ENSG00000172936 PMC6481333__F10 Microarray and pathway analysis of two COMMA-DB derived clones reveal important differences relevant to their developmental capacity in-vivo ENSG00000145604 ENSG00000094804 ENSG00000118007 ENSG00000101972 ENSG00000108055 ENSG00000132646 ENSG00000123374 ENSG00000205250 ENSG00000277273 ENSG00000117399 ENSG00000276876 PMC3463893__F2 The inductive and effector sites for the mucosal B-cell response in CD ENSG00000186716 ENSG00000173599 ENSG00000145321 PMC6801762__F1 Schematic presentation of the metabolic pathway and transporters that regulate the cellular polyamine levels ENSG00000168003 ENSG00000088826 ENSG00000175003 ENSG00000148832 ENSG00000112499 ENSG00000221955 ENSG00000146477 PMC5585869__F5 BCR–ABL pathway drives signaling in H929 cells and phosphorylation is inhibited by imatinib ENSG00000033327 ENSG00000186716 ENSG00000149308 ENSG00000160691 PMC4822708__F7 CD47 regulation of autophagy ENSG00000057663 PMC2676108__F3 INHIBITOR OF APOPTOSIS (IAP) PROTEINS IN EUKARYOTIC EVOLUTION AND DEVELOPMENT: A MODEL OF THEMATIC CONSERVATION ENSG00000102871 ENSG00000173039 ENSG00000168040 ENSG00000127191 PMC6148320__F2 Helicobacter pylori infection and inflammatory bowel disease ENSG00000165556 ENSG00000177169 ENSG00000162711 ENSG00000167207 ENSG00000125538 ENSG00000172936 ENSG00000175104 ENSG00000293532 PMC5396125__F1 Exome Analysis of Rare and Common Variants within the NOD Signaling Pathway ENSG00000023445 ENSG00000110330 ENSG00000167207 ENSG00000157625 ENSG00000106100 PMC2720375__F7 Genome-Wide Screen of Genes Required for Caffeine Tolerance in Fission Yeast ENSG00000166340 ENSG00000051180 ENSG00000123268 PMC4822708__F4 Functional crosstalk between CD36 and CD47 signaling ENSG00000135218 ENSG00000291971 PMC5813732__F7 Salvianolic Acid B Enhances Hepatic Differentiation of Human Embryonic Stem Cells Through Upregulation of WNT Pathway and Inhibition of Notch Pathway ENSG00000071564 ENSG00000019991 ENSG00000138795 ENSG00000133961 PMC3358449__F1 Key components in the regulation of methionine metabolism ENSG00000285250 PMC4133953__F8 Cell cycle regulation by miRNA and their targets dysregulated in cervical cancer ENSG00000135446 ENSG00000150907 ENSG00000123374 ENSG00000105810 PMC4133953__F9 Network for miRNAs involved in migration and invasion of cervical cancer cells ENSG00000185591 ENSG00000187764 ENSG00000109586 ENSG00000122194 PMC1618798__F2 Intrinsic apoptotic signaling pathway ENSG00000115718 PMC1618798__F3 Extrinsic apoptotic signaling pathway ENSG00000168040 ENSG00000026103 PMC5763483__F3 Potential cascade of molecular events leading to reduced differentiation of regulatory T cells for prevention of autoimmunity ENSG00000125810 ENSG00000049768 PMC7375019__F1 Activation of RAGE axis in Sars-Cov-2 infected cells in DM patients ENSG00000162711 ENSG00000197635 ENSG00000125538 ENSG00000189403 PMC9434547__F1 Lactate metabolism in human health and disease ENSG00000198492 ENSG00000118520 PMC7791181__F8 Working model of the target interaction axis after SCI After SCI, TGF‐B1 expression was increased, leading to phosphorylation of the Smad2/3 protein, thereby promoting miR‐21a‐5p upregulation PMC4631256__F2 Epigenetic Mechanisms in Schizophrenia ENSG00000084093 PMC5462018__F5 Conserved ABA signaling pathway in epidermis of H PMC5247472__F1 Vitamin D metabolism ENSG00000111012 ENSG00000118972 ENSG00000152266 ENSG00000105516 ENSG00000019186 ENSG00000186104 PMC7938641__F1 Hypothetical concept for the dysregulation of lung epithelial ion and fluid transport by SARS-CoV-2 ENSG00000130234 ENSG00000109062 ENSG00000001626 PMC3524194__F1 Upstream regulators of the Hippo pathway ENSG00000163914 ENSG00000198670 ENSG00000131023 PMC8898834__F2 Depletion and Dysfunction of Dendritic Cells: Understanding SARS-CoV-2 Infection ENSG00000088888 ENSG00000198793 PMC4444031__F4 Illustration of the Hedghog (Hh) signalling activation ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000177606 ENSG00000168036 PMC3023296__F3 Cell cycle, cellular growth and proliferation pathways detected by ingenuity pathways analysis ENSG00000242265 ENSG00000140323 ENSG00000120837 ENSG00000151465 ENSG00000006715 ENSG00000088038 ENSG00000148719 ENSG00000183484 PMC8824735__F1 Structure-based discovery of selective CYP17A1 inhibitors for Castration-resistant prostate cancer treatment PMC7655170__F9 Schematic mechanism underlying CUEDC1-suppressed NSCLC progression ENSG00000180891 PMC11983443__F1 Leptin and adiponectin in health and disease ENSG00000198793 ENSG00000168610 PMC9061764__F3 Mechanism identified for ketamine and/or (2 R, 6 R)-hydroxynorketamine (HNK) ENSG00000105835 ENSG00000198793 ENSG00000283060 ENSG00000267534 ENSG00000125968 ENSG00000172201 PMC4619206__F4 MAPK signaling pathway in CNVRs unique to the susceptible line ENSG00000087095 ENSG00000172680 ENSG00000170458 ENSG00000130522 ENSG00000130159 ENSG00000175104 ENSG00000127191 ENSG00000081189 ENSG00000196712 ENSG00000026103 PMC10605254__F5 PDLIMs and TGFB signaling pathway ENSG00000170365 ENSG00000196923 ENSG00000136153 ENSG00000075213 PMC10605254__F6 PDLIMs and MAPK and NFKB signaling pathway ENSG00000154553 ENSG00000196923 ENSG00000136153 ENSG00000120913 ENSG00000168610 ENSG00000182541 PMC10605254__F4 PDLIMs and integrin signaling pathway ENSG00000196923 ENSG00000136153 ENSG00000120913 PMC3539824__F2 Opening Pandora’s jar: a primer on the putative roles of CRMP2 in a panoply of neurodegenerative, sensory and motor neuron, and central disorders ENSG00000010810 PMC8773595__F1 Clinical Significance of the Duality of Wnt/Beta-Catenin Signaling in Human Hepatocellular Carcinoma ENSG00000168036 PMC7370863__F1 VG9/VD2 T‐cell response to microbial antigens and self‐phosphoantigens—the little things that give it away ENSG00000124508 ENSG00000292170 ENSG00000197429 PMC4265312__F2 TLX: A Master Regulator for Neural Stem Cell Maintenance and Neurogenesis ENSG00000154764 ENSG00000204531 ENSG00000075891 ENSG00000139352 PMC8773595__F2 Clinical Significance of the Duality of Wnt/Beta-Catenin Signaling in Human Hepatocellular Carcinoma ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC8734057__SF1 Intricate relationship between SARS-CoV-2–induced shedding and cytokine storm generation: A signaling inflammatory pathway augmenting COVID-19 ENSG00000130234 PMC2089068__F3 Relative transcript levels for genes from carbon central metabolism for PB12 (first value) and PB13 (second value), as compared to JM101 ENSG00000143252 ENSG00000197713 ENSG00000073578 ENSG00000122966 ENSG00000117118 ENSG00000197487 ENSG00000172005 PMC5833436__F8 miR-146a-5p and TLR4 signaling ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC2089068__F4 Relative transcript levels for genes from carbon central metabolism for L-Phe overproducing strains ENSG00000143252 ENSG00000197713 ENSG00000073578 ENSG00000122966 ENSG00000117118 ENSG00000197487 ENSG00000172005 ENSG00000153574 PMC3810677__F1 Regulation of the HIF pathway by oxygen dependant and independent mechanisms (a) Under normoxia, prolyl hydroxylase domain proteins use oxygen and Alpha-ketoglutarate as substrates to hydroxylate conserved proline residues on HIFA subunits ENSG00000167772 ENSG00000134086 ENSG00000198793 PMC7243250__F6 Signaling pathway of Bak’s neuroprotective effect against SAH injury which is suggested in the present study ENSG00000265972 ENSG00000100985 PMC5755503__F2 Genetic alterations that lead to HIF activation in GBM ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC12129981__F1 Research and progress of cGAS/STING/NLRP3 signaling pathway: a mini review ENSG00000183735 ENSG00000164430 PMC12129981__F2 Research and progress of cGAS/STING/NLRP3 signaling pathway: a mini review ENSG00000162711 ENSG00000183735 ENSG00000164430 PMC11617312__F3 Canonical Wnt/Beta-catenin signalling in epithelial homeostasis and HPV-modulated homeostasis ENSG00000134982 ENSG00000168036 ENSG00000109062 ENSG00000196470 PMC10342868__F8 Regulatory mechanism of lncRNA 220 ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000121879 PMC8695500__F2 Immune Modulation as a Key Mechanism for the Protective Effects of Remote Ischemic Conditioning After Stroke ENSG00000177169 ENSG00000107562 ENSG00000002330 ENSG00000170458 ENSG00000121966 PMC11591885__F2 Leu supplementation leads to tumor cell death by inducing apoptosis and oxidative stress PMC8146072__F5 Metabolic Reprogramming in Cancer Cells Supporting Enhanced Growth and Proliferation ENSG00000197713 PMC11591885__F1 Action of Leu and its metabolites ENSG00000145979 ENSG00000108443 ENSG00000103257 ENSG00000105552 ENSG00000285069 ENSG00000187840 PMC4811915__F9 Proposed model for the role of the Wnt/Beta-catenin pathway during odontogenesis ENSG00000168036 PMC9963318__F3 MYC2: A Master Switch for Plant Physiological Processes and Specialized Metabolite Synthesis ENSG00000101751 ENSG00000104973 ENSG00000166169 PMC8329443__F3 Vital Roles of LINC00662 in Human Cancers ENSG00000139926 ENSG00000131023 PMC6628350__F8 Liraglutide attenuates diabetes-associated neointima formation and pathogenic EndMT via the AMPK pathway ENSG00000125538 PMC4561307__F8 The changes in soleus muscle gene expression within the TGFB and BMP pathways, with SCI (a) and acute response to treadmill training (b) ENSG00000170365 ENSG00000137834 ENSG00000134363 PMC8327397__F6 Sphingolipid metabolism and the enzymes directly participating in the ceramide synthesis pathway ENSG00000100422 ENSG00000102172 ENSG00000106546 PMC7458277__F5 Interaction network derived from the pathway analysis according to results of the genome-wide association study [GWAS] meta-analysis ENSG00000136158 ENSG00000004975 ENSG00000288174 ENSG00000132182 ENSG00000038382 ENSG00000105664 ENSG00000116106 ENSG00000153879 ENSG00000185231 ENSG00000113749 ENSG00000197943 ENSG00000113532 ENSG00000154654 ENSG00000006116 ENSG00000184575 PMC8329443__F2 Vital Roles of LINC00662 in Human Cancers ENSG00000070831 ENSG00000163914 PMC8717932__F1 Targeting Programmed Cell Death to Improve Stem Cell Therapy: Implications for Treating Diabetes and Diabetes-Related Diseases ENSG00000278718 ENSG00000144848 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000164305 PMC6499473__F1 A Developing Therapeutic Decision Tree for Ductal Breast Cancer with Emphasis on the TNBC Subtype ENSG00000124102 ENSG00000135446 ENSG00000105810 PMC11873181__F2 Regulation of mitochondrial quality control by PGAM5 ENSG00000281324 ENSG00000162337 ENSG00000175193 ENSG00000134982 ENSG00000168036 ENSG00000247077 PMC7226287__F8 BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma ENSG00000183682 ENSG00000122779 ENSG00000079999 PMC7467727__F5 MTOR regulation of oRG morphology ENSG00000070831 ENSG00000198793 PMC6941425__F6 Targeting citrulline-specific B-cells using a CCP-STAL ENSG00000186716 PMC4949115__F2 M2a polarization ENSG00000105397 ENSG00000137265 ENSG00000105639 PMC9094111__F1 Calcium Mediated Cold Acclimation in Plants: Underlying Signaling and Molecular Mechanisms ENSG00000110395 ENSG00000136997 PMC5795461__F1 Verdinexor Targeting of CRM1 is a Promising Therapeutic Approach against RSV and Influenza Viruses ENSG00000174123 ENSG00000162711 ENSG00000167207 ENSG00000136869 ENSG00000276561 ENSG00000164342 PMC5113305__F1 Molecular mechanisms supporting the proliferation of HCC cells despite serum withdrawal ENSG00000112972 ENSG00000185591 ENSG00000083720 ENSG00000275544 ENSG00000117305 PMC8441304__F6 SUMO‐mediated DNA replication‐independent DPC repair ENSG00000010072 ENSG00000183763 ENSG00000063978 PMC8927970__F1 Toll-Like Receptor Signaling and Its Role in Cell-Mediated Immunity ENSG00000150455 ENSG00000127191 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000134070 ENSG00000157625 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC8185231__F1 Vitamin D: Possible Therapeutic Roles in Hepatocellular Carcinoma ENSG00000147649 ENSG00000196591 ENSG00000265972 ENSG00000081051 ENSG00000168610 PMC9231436__F2 Next-Generation Anti-Angiogenic Therapies as a Future Prospect for Glioma Immunotherapy; From Bench to Bedside ENSG00000132906 ENSG00000019991 ENSG00000281324 ENSG00000002330 ENSG00000162337 ENSG00000134982 ENSG00000138798 ENSG00000137193 ENSG00000168036 ENSG00000180210 ENSG00000122025 ENSG00000127445 ENSG00000049130 ENSG00000069482 ENSG00000163235 ENSG00000135446 ENSG00000163914 ENSG00000146648 PMC8359396__F1 Pharmacological validation of TDO as a target for Parkinson’s disease ENSG00000162882 PMC5654107__F5 Model of metabolic processes upregulated in aerial and in root cells ENSG00000146909 ENSG00000100412 ENSG00000118520 ENSG00000114315 ENSG00000124253 ENSG00000169299 PMC3931120__F7 In Utero Exposure to Second-Hand Smoke Aggravates the Response to Ovalbumin in Adult Mice ENSG00000288411 ENSG00000038427 ENSG00000131747 ENSG00000108688 ENSG00000106178 PMC6139224__F6 Diseases and functions analysis by integrated pathway analysis using 20 MeDEGs ENSG00000027075 ENSG00000101160 ENSG00000100448 ENSG00000181104 ENSG00000020633 ENSG00000111321 ENSG00000180644 ENSG00000277571 ENSG00000011422 ENSG00000066336 ENSG00000010810 ENSG00000076641 ENSG00000263238 PMC6195682__F4 Cytokine/chemokine driven JAK-STAT pathway in transgenic spleen ENSG00000213928 ENSG00000117228 ENSG00000112964 ENSG00000119535 ENSG00000291971 ENSG00000125388 ENSG00000183625 ENSG00000157601 ENSG00000137193 ENSG00000232326 ENSG00000244731 ENSG00000166278 ENSG00000121807 ENSG00000276561 ENSG00000182326 ENSG00000169245 ENSG00000108691 ENSG00000134574 ENSG00000145623 ENSG00000170458 ENSG00000163131 ENSG00000108688 ENSG00000104432 ENSG00000104081 PMC5789890__F3 Representation of the DNA methylation modifications that occurred within the PI3K/AKT KEGG pathway following 7 weeks of reloading in human subjects ENSG00000065833 ENSG00000002330 ENSG00000186716 ENSG00000198793 PMC3615616__F1 Self-renewal and differentiation of gastric stem cells ENSG00000164379 ENSG00000138798 ENSG00000184956 ENSG00000096088 ENSG00000160182 ENSG00000160181 ENSG00000143933 ENSG00000169605 ENSG00000291363 ENSG00000115457 ENSG00000143761 ENSG00000149485 ENSG00000164690 PMC6491463__F3 Schematic depiction of the CD38/CD203a/CD73 adenosinergic pathway as a major mechanism of the acquired resistance to anti-PD-1/PD-L1 blockade within the BM niche PMC6491463__F1 The purinome in the MM environment under bone marrow niche metabolic reprogramming ENSG00000196839 PMC3888787__F1 Bile acid synthesis occurs by two pathways, the classic ‘neutral’ pathway and the alternative ‘acidic’ pathway ENSG00000167910 ENSG00000099377 ENSG00000122787 ENSG00000135929 PMC5691655__F1 DNA damage repair (DDR) factors regulate cccDNA formation, expression, and degradation ENSG00000198887 ENSG00000122008 PMC5691655__F2 HBV components interact with DDR pathways and proteins ENSG00000198887 ENSG00000167986 PMC3383804__F5 HCMV management of the PI3K/AKT/mTOR pathway ENSG00000164327 PMC8540355__F1 Pathogenesis, Molecular Mechanisms, and Therapeutic Potential of the Interferon Pathway in Systemic Lupus Erythematosus and Other Autoimmune Diseases ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC9266881__F2 Ca2+ Signalling and Hypoxia/Acidic Tumour Microenvironment Interplay in Tumour Progression ENSG00000164879 ENSG00000133107 ENSG00000144935 ENSG00000167323 ENSG00000293604 ENSG00000198793 ENSG00000137672 ENSG00000072315 ENSG00000168610 ENSG00000146648 PMC8507780__F10 Alterations in HLA Class I-Presented Immunopeptidome and Class I-Interactome upon Osimertinib Resistance in EGFR Mutant Lung Adenocarcinoma ENSG00000273686 ENSG00000205220 ENSG00000110046 ENSG00000113441 ENSG00000139722 PMC9316990__F3 Potential Roles of Dietary Anthocyanins in Inhibiting Vascular Endothelial Cell Senescence and Preventing Cardiovascular Diseases ENSG00000149311 ENSG00000175054 PMC8065041__F10 This study ENSG00000177575 ENSG00000049768 ENSG00000168610 ENSG00000007171 PMC8144465__F4 Cannabidiol Modulates Mitochondrial Redox and Dynamics in MCF7 Cancer Cells: A Study Using Fluorescence Lifetime Imaging Microscopy of NAD(P)H ENSG00000196689 PMC7672029__F4 Flowering and sex determination metabolic pathways: identification of candidate genes underneath the QTLs ENSG00000088926 PMC5719056__F1 The mevalonate pathway leads to cholesterol synthesis ENSG00000160752 ENSG00000113161 PMC9463773__F1 Diversification of PAR signaling through receptor crosstalk ENSG00000134982 ENSG00000163914 PMC9463773__F2 Diversification of PAR signaling through receptor crosstalk ENSG00000291971 ENSG00000138798 ENSG00000163914 ENSG00000136869 ENSG00000074410 PMC4588110__F1 PI3Ks signaling during G2/M progression and mitosis phase ENSG00000134982 ENSG00000166851 PMC5596340__F5 Metabolic reconstruction of the candidate phylum members PAUC34f, Parcubacteria (OD1), Peregrinibacteria, and ACD39 (Bin 13) ENSG00000169291 PMC7157488__F1 Crosstalk between RNA metabolism and cellular stress responses during Zika virus replication ENSG00000145388 ENSG00000183735 ENSG00000088888 ENSG00000144895 ENSG00000136869 ENSG00000091542 ENSG00000164342 PMC2615542__F2 Luteolin, a flavonoid with potentials for cancer prevention and therapy ENSG00000173039 ENSG00000168040 PMC3880642__F1 Smoking and microRNA dysregulation: a cancerous combination ENSG00000169554 ENSG00000002330 ENSG00000145147 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000189283 ENSG00000145604 ENSG00000163235 ENSG00000136997 ENSG00000171759 ENSG00000136869 ENSG00000105810 ENSG00000146648 PMC8994563__F7 Targets Exploration of Hydroxychloroquine for Pigmentation and Cell Protection Effect in Melanocytes: The Clue for Vitiligo Treatment ENSG00000047579 ENSG00000115648 ENSG00000185664 ENSG00000188428 ENSG00000163945 ENSG00000135903 ENSG00000174099 ENSG00000141744 ENSG00000087085 ENSG00000100146 PMC4111847__F4 Glycolysis and the triacylglycerol biosynthetic pathway in Cp0710 ENSG00000100294 PMC6624447__F5 Canonical pathways generated in Ingenuity Pathway Analysis of interferon signaling pathway of DEGs in (A) T helper cells, (B) T cytotoxic cells, (C) monocytes, and (D) B lymphocytes of infected goats at 9 dpi ENSG00000068079 ENSG00000213928 ENSG00000105397 ENSG00000197296 ENSG00000185201 ENSG00000033800 ENSG00000185745 ENSG00000230034 PMC6624447__F6 Canonical pathways generated in Ingenuity Pathway Analysis of Oncostatin M signaling pathway of DEGs in (A) T helper cells, (B) T cytotoxic cells, (C) monocytes, and (D) B lymphocytes of infected goats at 9 dpi ENSG00000100234 ENSG00000133048 ENSG00000145623 ENSG00000099985 ENSG00000125148 ENSG00000149968 PMC6769697__F1 Schematic depiction of copper and platinum distribution in tumor cell ENSG00000173992 ENSG00000138495 ENSG00000123191 ENSG00000177556 PMC9100382__F3 Reactive and Senescent Astroglial Phenotypes as Hallmarks of Brain Pathologies ENSG00000144366 ENSG00000183098 ENSG00000145794 ENSG00000189403 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000168610 ENSG00000283100 PMC3159179__F4 Methionine-Hcy metabolism PMC6315366__F4 Autophagy, Keap1 and p62 regulate Nrf2 in HCC ENSG00000177169 ENSG00000183735 ENSG00000198793 ENSG00000079999 PMC3699421__F2 Reactivation of HIV-1 transcriptional latency ENSG00000101945 ENSG00000186834 PMC2593508__F8 Fasudil inhibits the myogenic response in the fetal pulmonary circulation ENSG00000163914 ENSG00000145321 PMC5394422__F2 The autophagy pathway and core autophagy proteins ENSG00000177169 ENSG00000110497 ENSG00000152348 ENSG00000198382 ENSG00000083290 ENSG00000126775 ENSG00000157954 ENSG00000136874 ENSG00000057663 ENSG00000005893 ENSG00000144848 ENSG00000070540 ENSG00000145782 PMC9569062__F5 Advances in the modulation of ROS and transdermal administration for anti-psoriatic nanotherapies ENSG00000214285 PMC9374593__F8 Working model that PFKFB3 inhibition plays an important role of deregulating cancer stemness, EMT and chemosensitivity in small cell lung cancer ENSG00000180210 ENSG00000186575 ENSG00000026508 ENSG00000118777 ENSG00000131023 PMC8236950__F5 Expression of ACE2, Soluble ACE2, Angiotensin I, Angiotensin II and Angiotensin-(1-7) Is Modulated in COVID-19 Patients ENSG00000130234 ENSG00000184012 ENSG00000168610 PMC5011664__F3 Regulation of wingless/int-1 signaling by crosstalk in hepatocellular carcinoma ENSG00000019991 ENSG00000168036 ENSG00000168646 PMC5386661__F10 Therapy-induced developmental reprogramming of prostate cancer cells and acquired therapy resistance ENSG00000168283 ENSG00000029559 ENSG00000197971 ENSG00000131095 ENSG00000205927 PMC9058112__F1 Cardiac Remodeling in Heart Failure: Role of Pyroptosis and Its Therapeutic Implications ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000174885 ENSG00000091592 ENSG00000091106 ENSG00000185792 PMC8165101__F5 Small molecules in targeted cancer therapy: advances, challenges, and future perspectives ENSG00000106571 ENSG00000128602 PMC8226042__F1 Immunological response to COVID-19 and its role as a predisposing factor in invasive aspergillosis ENSG00000130234 PMC8165101__F6 Small molecules in targeted cancer therapy: advances, challenges, and future perspectives ENSG00000100290 PMC8165101__F7 Small molecules in targeted cancer therapy: advances, challenges, and future perspectives ENSG00000149311 ENSG00000175054 ENSG00000083093 ENSG00000051180 ENSG00000149554 ENSG00000183765 PMC3224542__F1 Genes related with the tau protein phosphatase-2A (PP2A) pathway ENSG00000127445 ENSG00000221914 ENSG00000205629 PMC3394960__F10 A schematic model for the role of ANXA2 in the pathogenesis of adenomyosis ENSG00000182718 ENSG00000168036 ENSG00000112715 PMC2933174__F6 Model depicting a novel mechanism by which cetuximab induces autophagy ENSG00000138798 ENSG00000198793 ENSG00000171791 PMC3317440__F2 Strain-specific host gene networks activated in Mtb-infected BMM ENSG00000096996 ENSG00000153814 ENSG00000120899 ENSG00000116353 ENSG00000113070 ENSG00000138798 ENSG00000114737 ENSG00000126353 ENSG00000115232 ENSG00000168610 ENSG00000132170 PMC3174390__F1 TGFB/Smads and crosstalk pathways in renal fibrosis and inflammation ENSG00000125538 PMC9503046__F4A Antimicrobial Peptides and Biomarkers Induced by Ultraviolet Irradiation Have the Potential to Reduce Endodontic Inflammation and Facilitate Tissue Healing ENSG00000138798 ENSG00000113070 ENSG00000169032 ENSG00000166670 ENSG00000135341 ENSG00000127191 ENSG00000006062 ENSG00000066468 ENSG00000111537 ENSG00000172216 ENSG00000163235 ENSG00000019549 ENSG00000140285 ENSG00000164400 ENSG00000100985 ENSG00000175104 ENSG00000146648 PMC11607510__F3 Glucose metabolism reprogramming of VECs ENSG00000180210 ENSG00000084734 ENSG00000137193 ENSG00000162692 ENSG00000159399 PMC7267399__F2 Possible life cycle of SARS‐CoV‐2 and potential intervention strategy ENSG00000130234 ENSG00000184012 PMC3174390__F4 Inhibitory role of Smad7 in renal fibrosis and inflammation ENSG00000125538 PMC11607510__F4 Glucose metabolism reprogramming of VECs in atherosclerosis ENSG00000130164 ENSG00000170558 ENSG00000198793 ENSG00000067900 ENSG00000078237 ENSG00000162692 ENSG00000142082 ENSG00000132356 ENSG00000057663 PMC6850169__F1 Simplified lipid metabolic pathway in maize ENSG00000198408 ENSG00000198670 ENSG00000184207 ENSG00000026103 PMC6748048__F1 Kinase Activation Mechanisms in the Hippo Kinase Cascade ENSG00000186575 ENSG00000163681 ENSG00000115808 ENSG00000111790 PMC4463932__F2 Glycosylation pathway defects with known immunologic consequences ENSG00000141349 ENSG00000171135 ENSG00000164414 ENSG00000033011 ENSG00000182858 ENSG00000281500 ENSG00000013375 PMC6748048__F3 Upstream Regulators of the Hippo Pathway in Drosophila and Mammals ENSG00000126016 ENSG00000186575 ENSG00000142192 ENSG00000130545 ENSG00000173404 ENSG00000291971 ENSG00000144560 ENSG00000163914 ENSG00000172936 ENSG00000150457 ENSG00000132849 ENSG00000072415 PMC6748048__F4 Hippo Pathway Mutations in Human Diseases ENSG00000186575 ENSG00000088256 ENSG00000150457 ENSG00000131023 PMC6506890__F4 Mevalonate Pathway ENSG00000160752 ENSG00000067064 ENSG00000110921 ENSG00000112972 ENSG00000152904 ENSG00000113161 ENSG00000120437 ENSG00000075239 ENSG00000148377 PMC11577197__F1 CD8+ T cell differential hierarchy upon antigen exposure ENSG00000139187 ENSG00000181847 ENSG00000126353 ENSG00000198846 PMC7005447__F5 Proteomics-guided metabolite supplementation strategy for arRP ENSG00000074800 ENSG00000073578 ENSG00000100412 ENSG00000169710 ENSG00000166278 ENSG00000105953 ENSG00000131828 ENSG00000159399 ENSG00000062485 PMC11577197__F2 Immunoediting in acute myeloid leukemia: Reappraising T cell exhaustion and the aberrant antigen processing machinery in leukemogenesis ENSG00000181847 ENSG00000156127 ENSG00000104894 ENSG00000137265 ENSG00000198846 PMC9519863__F2 Gut microbiota–bile acid axis: A potential therapeutic target for liver fibrosis ENSG00000162711 ENSG00000150782 ENSG00000063176 ENSG00000081041 ENSG00000180432 ENSG00000172936 ENSG00000136869 PMC8834247__F4 Put in a “Ca2+ll” to Acute Myeloid Leukemia ENSG00000107562 ENSG00000121966 PMC8834247__F5 Put in a “Ca2+ll” to Acute Myeloid Leukemia ENSG00000291603 ENSG00000111537 ENSG00000156127 ENSG00000137265 PMC3721836__F9 Simplified model of Rac1 signaling and function in learning-induced adult neurogenesis ENSG00000177606 ENSG00000077279 ENSG00000099860 PMC8834247__F3 Put in a “Ca2+ll” to Acute Myeloid Leukemia ENSG00000149311 ENSG00000293604 ENSG00000173120 ENSG00000116688 ENSG00000198793 ENSG00000168040 ENSG00000140464 ENSG00000026103 PMC4367602__F2 Ligand stimulation of ERK and PI3K signaling in BRAFV600E melanomas ENSG00000136158 ENSG00000019991 ENSG00000157764 ENSG00000138798 PMC8081956__F3 Autophagy in Hepatic Steatosis: A Structured Review ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000126775 ENSG00000144848 ENSG00000145782 ENSG00000057663 ENSG00000079999 PMC2878851__F3 Protein Interaction Network Underpins Concordant Prognosis Among Heterogeneous Breast Cancer Signatures ENSG00000087245 ENSG00000005339 ENSG00000178999 ENSG00000134982 ENSG00000131153 ENSG00000113140 ENSG00000163064 ENSG00000074319 ENSG00000112118 ENSG00000065328 ENSG00000112242 ENSG00000115415 ENSG00000134057 ENSG00000132646 ENSG00000047849 PMC6023743__F1 A well-studied example of modulation of phospholipid signal transduction cascade in the nucleus is turnover of inositol phospholipids, especially phosphatidylinositol-4,5-bisphosphate (PIP2) ENSG00000129219 ENSG00000173599 ENSG00000198670 ENSG00000182621 ENSG00000124181 PMC5910322__F6 Pro-apoptotic mechanisms of miR-217-5p regulating the ERK-MAPK pathway at different sites ENSG00000002330 ENSG00000157764 ENSG00000163558 ENSG00000151929 ENSG00000171791 PMC1635984__F3 MRNA expression levels in TGFBeta-treated T84 epithelial cells compared to control cell culture ENSG00000004975 ENSG00000162552 ENSG00000087095 ENSG00000138795 ENSG00000005339 ENSG00000134982 ENSG00000138798 ENSG00000115904 ENSG00000174804 ENSG00000168036 ENSG00000100485 ENSG00000100387 ENSG00000113558 ENSG00000106070 ENSG00000146648 ENSG00000126458 PMC9335290__F2 CircRNA ITCH: Insight Into Its Role and Clinical Application Prospect in Tumor and Non-Tumor Diseases ENSG00000078747 ENSG00000170558 ENSG00000198793 ENSG00000173599 ENSG00000168036 ENSG00000141568 PMC2878851__F1 Protein Interaction Network Underpins Concordant Prognosis Among Heterogeneous Breast Cancer Signatures ENSG00000117650 ENSG00000178573 ENSG00000134057 ENSG00000134982 ENSG00000113140 ENSG00000112118 ENSG00000124762 ENSG00000117399 PMC7797150__F4 Prediction of target genes and circRNA-miRNA-mRNA network ENSG00000121989 ENSG00000186480 ENSG00000100485 ENSG00000177426 ENSG00000157625 ENSG00000172201 ENSG00000128989 ENSG00000101109 ENSG00000144560 ENSG00000042429 ENSG00000148572 ENSG00000117152 ENSG00000153561 ENSG00000163235 ENSG00000130508 ENSG00000162692 ENSG00000178951 ENSG00000161405 ENSG00000135966 ENSG00000176679 ENSG00000172315 ENSG00000104332 ENSG00000172159 ENSG00000141298 ENSG00000080298 ENSG00000121406 ENSG00000136052 ENSG00000164411 ENSG00000166317 ENSG00000128283 ENSG00000149658 ENSG00000048707 ENSG00000168461 ENSG00000139579 ENSG00000132388 ENSG00000232119 ENSG00000166847 ENSG00000108256 ENSG00000135503 ENSG00000091640 ENSG00000215301 ENSG00000153779 ENSG00000135447 ENSG00000114520 ENSG00000118058 ENSG00000281178 ENSG00000168876 ENSG00000109133 ENSG00000090863 ENSG00000100321 ENSG00000128699 ENSG00000070404 ENSG00000168758 ENSG00000180787 ENSG00000107863 ENSG00000213551 ENSG00000164284 ENSG00000165219 ENSG00000121350 ENSG00000140090 ENSG00000275066 ENSG00000275023 ENSG00000116106 ENSG00000158270 ENSG00000171848 ENSG00000291555 PMC3874316__F7 Antcin C-induced upregulation of antioxidative gene expression via the Nrf2/ARE signaling pathway and suppression of AAPH-induced apoptosis in human hepatic HepG2 cells ENSG00000181019 ENSG00000178573 ENSG00000120868 ENSG00000171791 ENSG00000079999 PMC6381446__F2 Schematic representation of the role of oxysterols in the Hh signalling pathway ENSG00000164690 ENSG00000128602 PMC2686735__F5 Map of BCR-pathway ENSG00000095585 ENSG00000100290 ENSG00000169291 ENSG00000002330 ENSG00000070831 ENSG00000141968 PMC7308426__F5 Calcium signaling pathway ENSG00000182533 ENSG00000293604 ENSG00000156026 ENSG00000186716 ENSG00000148175 ENSG00000163631 PMC7308426__F6 Pathway in cancer PMC5814934__F6 Working model ENSG00000141867 ENSG00000168214 ENSG00000148400 PMC9146014__F1 Broad Antiviral Strategy: Inhibitors of Human DHODH Pave the Way for Host-Targeting Antivirals against Emerging and Re-Emerging Viruses ENSG00000162368 ENSG00000158825 ENSG00000143179 ENSG00000102967 ENSG00000084774 PMC5977747__F2 Possible scenarios for PanDrugs therapeutic candidates ENSG00000019991 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8980477__F1 Contribution of Interleukin-17A to Retinal Degenerative Diseases ENSG00000082512 ENSG00000056736 ENSG00000175104 ENSG00000127191 ENSG00000163702 ENSG00000076604 PMC5997132__F4 Main pathway targeted using siRNA delivery systems in oral cancer.Notes: Examples of siRNA therapeutics alter multiple hallmarks applied for oral cancer ENSG00000170961 ENSG00000167772 ENSG00000124766 ENSG00000151929 ENSG00000121966 ENSG00000163507 PMC3823960__F6 Summary of retinoid pathway ENSG00000095596 ENSG00000121207 ENSG00000003137 PMC9671909__F6 Norepinephrine transporter defects lead to sympathetic hyperactivity in Familial Dysautonomia models PMC8347567__F10 Fedratinib Attenuates Bleomycin-Induced Pulmonary Fibrosis via the JAK2/STAT3 and TGFB1 Signaling Pathway ENSG00000168610 PMC3607680__F3 The one carbon cycle PMC5080925__F6 Model showing association of PAX5, CD19, CD3, p53, Ras, Raf, MAPK and Zap70 in B-cell and T-cell type non-Hodgkin's lymphoma ENSG00000177455 ENSG00000291603 ENSG00000196092 PMC4292048__F3 TRAF4 function on TJs ENSG00000135655 ENSG00000198742 ENSG00000076604 PMC6078642__F7 Enzymes necessary for local aldosterone synthesis are present in muscle-derived leukocytes ENSG00000179142 PMC6763548__F1 Scheme illustrating the actions of adiponectin/AdipoR agonist, AdipoRon, in the liver and the muscle ENSG00000004660 ENSG00000159346 ENSG00000285070 ENSG00000175567 ENSG00000096717 PMC3439965__F3 Simplified overview of the canonical Wnt signaling pathway ENSG00000134982 PMC4118716__F2 Involvement of the Janus Kinase/Signal Transducer and Activator of Transcription Signaling Pathway in Multiple Sclerosis and the Animal Model of Experimental Autoimmune Encephalomyelitis ENSG00000138378 ENSG00000105397 ENSG00000125538 ENSG00000107485 ENSG00000105639 ENSG00000168610 PMC7879595__F2 Among P2X receptors, the P2X7 is highlighted within the context of BC ENSG00000105656 ENSG00000026508 ENSG00000168036 PMC7879595__F1 The TME of solid tumors has the common characteristic of hypoxia (1% O2), which is due to a low supply of nutrients and oxygen ENSG00000171791 PMC5514966__F4 Role of EZH2 in cancer stem cells: from biological insight to a therapeutic target ENSG00000148400 ENSG00000168036 ENSG00000168610 PMC3390960__F1 Formation of the COPII vesicle on the surface of the endoplasmic reticulum ENSG00000152700 ENSG00000101310 ENSG00000100934 ENSG00000138674 ENSG00000176986 ENSG00000075826 PMC3417062__F7 Molecular mechanisms underlying PA and histologically anaplastic PA ENSG00000157764 ENSG00000146648 ENSG00000196712 PMC7923229__F3 TRIM5Alpha-mediated regulation of innate immune signaling and molecular inflammation ENSG00000177169 ENSG00000157625 ENSG00000136869 ENSG00000175104 PMC9237441__F5 Molecular Pathways and Roles for Vitamin K2-7 as a Health-Beneficial Nutraceutical: Challenges and Opportunities ENSG00000167601 ENSG00000002330 ENSG00000120868 ENSG00000171791 ENSG00000168610 PMC6054220__F2 Autophagy induced by nutrient and nutrition stresses via the mTOR and AMPK signal pathways ENSG00000198793 ENSG00000155792 ENSG00000167965 PMC4218725__F6 Shigella dysenteriae Modulates BMP Pathway to Induce Mucin Gene Expression In Vivo and In Vitro ENSG00000165556 ENSG00000291363 ENSG00000293532 PMC5527897__F2 N‐linked glycosylation ENSG00000101901 ENSG00000168282 ENSG00000139133 ENSG00000033011 ENSG00000159063 ENSG00000088035 ENSG00000214160 ENSG00000117620 ENSG00000128268 PMC4051845__F1 DNA double-strand break repair pathway choice and cancer ENSG00000012048 ENSG00000080345 PMC8268913__F6 Transcriptional Modulation of the Hippo Signaling Pathway by Drugs Used to Treat Bipolar Disorder and Schizophrenia ENSG00000186575 ENSG00000168036 ENSG00000131023 PMC8365911__F4 Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants ENSG00000067141 ENSG00000253293 ENSG00000139514 ENSG00000092445 ENSG00000117868 ENSG00000198755 ENSG00000187720 ENSG00000101782 ENSG00000159461 ENSG00000127528 ENSG00000112118 ENSG00000010278 ENSG00000148344 ENSG00000138356 ENSG00000053747 ENSG00000122756 ENSG00000167779 ENSG00000136997 ENSG00000141753 ENSG00000158825 ENSG00000013016 ENSG00000100906 ENSG00000204103 ENSG00000143878 ENSG00000163453 ENSG00000116717 ENSG00000049860 ENSG00000148848 ENSG00000165795 ENSG00000106617 ENSG00000117020 ENSG00000171914 ENSG00000102760 ENSG00000146122 ENSG00000179941 ENSG00000106624 ENSG00000090530 ENSG00000112306 ENSG00000114166 ENSG00000184205 PMC5527897__F5 Ganglio‐series glycosphingolipid synthesis pathway ENSG00000008513 ENSG00000135454 ENSG00000111728 ENSG00000160408 ENSG00000148154 PMC4118716__F4 M1 and M2 macrophage polarization ENSG00000169245 ENSG00000102962 ENSG00000108691 ENSG00000275385 ENSG00000125538 ENSG00000102970 PMC2712666__F3 TNF superfamily: costimulation and clinical applications ENSG00000139193 ENSG00000124102 ENSG00000127191 PMC7607850__F1 ZA inhibits the RANKL/RANK pathway ENSG00000198793 ENSG00000175104 ENSG00000131196 PMC5509628__F2 Cav1.2 and Cav1.3 signaling mechanisms ENSG00000144895 ENSG00000074410 PMC4811021__F1 Diagrams of the Hippo signaling pathway in (A) Drosophila melanogaster and (B) mammals highlight the core kinase cascade and upstream regulatory signals ENSG00000131023 PMC7855207__F1 Expanding the Clinical and Metabolic Phenotype of DPM2 deficient Congenital Disorders of Glycosylation ENSG00000000419 ENSG00000136908 PMC9639813__F6 Key neuronal signalling pathways are downregulated in fast growing in vivo juvenile liver fluke ENSG00000102003 ENSG00000127948 PMC9602136__F14 Deciphering the Key Regulatory Roles of KLF6 and Bta-miR-148a on Milk Fat Metabolism in Bovine Mammary Epithelial Cells ENSG00000065833 ENSG00000100979 PMC7762867__F1 Inflammatory signaling pathway in macrophages ENSG00000109320 ENSG00000172005 ENSG00000173039 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC2847521__F11 Proposed model for the I3C disruption of a cross-regulatory positive feedback loop involving expression of GATA3 and ERA by stimulating the degradation of ERA protein ENSG00000100387 ENSG00000107485 ENSG00000106546 PMC5777301__F1 Type I Interferon signaling pathway ENSG00000184979 ENSG00000213928 ENSG00000187608 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC6349473__F2 Developmental processes regulate craniofacial variation in disease and evolution ENSG00000137834 ENSG00000140262 ENSG00000122691 ENSG00000164690 ENSG00000128602 PMC11820753__F3 Impact of CR on different nutritional pathways indicating how it promotes anti-cancer activity ENSG00000198793 ENSG00000140443 PMC6874456__F8 Schematic model of how TG NPs ameliorate CKD progression ENSG00000042832 ENSG00000214285 PMC3670604__F4 Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma ENSG00000188486 ENSG00000160789 ENSG00000213614 ENSG00000120885 ENSG00000083312 ENSG00000112715 PMC1415320__F6 The proposed TGFB1 signaling mechanism that promotes EMT ENSG00000168036 PMC3124345__F2 Schematic representation of the possible mechanisms leading to ovarian cysts in female patients with ORD ENSG00000001630 ENSG00000127948 PMC7708424__F5 An example of where Pascal pathway enrichment and HotNet2 home in on the same pathway causal of Hyperlipidaemia ENSG00000007944 ENSG00000130208 ENSG00000073060 ENSG00000130164 ENSG00000135100 ENSG00000110244 ENSG00000138823 ENSG00000160179 ENSG00000134243 ENSG00000158874 ENSG00000169174 PMC9386081__F1 Non-coding RNAs in necroptosis, pyroptosis, and ferroptosis in cardiovascular diseases ENSG00000278718 ENSG00000162711 ENSG00000102871 ENSG00000167468 ENSG00000168404 ENSG00000285379 PMC4778854__F3 Changes in the expression levels of genes associated with cell cycle pathway in PC3 cell line after treatment with G ENSG00000134982 ENSG00000100842 ENSG00000250254 ENSG00000118971 ENSG00000253729 PMC11566483__F4 Caspase-3/8/9- and granzyme-mediated pathways ENSG00000278718 ENSG00000137275 ENSG00000145649 ENSG00000168040 ENSG00000147697 ENSG00000285379 ENSG00000073605 PMC8699546__F6 Post-Translational Modification of HMGB1 Disulfide Bonds in Stimulating and Inhibiting Inflammation ENSG00000272398 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC8699546__F3 Post-Translational Modification of HMGB1 Disulfide Bonds in Stimulating and Inhibiting Inflammation ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC11566483__F2 NLRP3 inflammasome construction and activation ENSG00000278718 ENSG00000162711 ENSG00000159335 PMC11519594__F6 Mechanism diagram of m6A-autophagy-mediated tumor treatment resistance ENSG00000177169 ENSG00000198492 ENSG00000198793 ENSG00000158828 ENSG00000100852 ENSG00000126261 ENSG00000172795 ENSG00000232112 ENSG00000057663 ENSG00000136231 ENSG00000149658 ENSG00000284099 ENSG00000165819 PMC11519594__F7 M6A autophagy axis involved in tumor signaling pathway network ENSG00000122566 ENSG00000145388 ENSG00000188554 ENSG00000149658 ENSG00000078804 ENSG00000136231 PMC6857915__F6 Gene expression microarray public dataset reanalysis in chronic obstructive pulmonary disease ENSG00000087095 ENSG00000095739 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000183579 ENSG00000168036 ENSG00000196470 ENSG00000185269 ENSG00000166526 PMC6857915__F7 Chronic obstructive pulmonary disease ENSG00000123999 ENSG00000104899 ENSG00000042832 ENSG00000117400 ENSG00000156574 ENSG00000113520 ENSG00000104432 PMC8573870__F11 Effect of macrophage polarization on the expression of the oxytocin signalling system in enteric neurons ENSG00000125538 ENSG00000113520 ENSG00000168610 ENSG00000198300 PMC10311769__F2 Revealing of a novel double bond reductase related to perilla ketone biosynthesis in Perilla frutescens ENSG00000110921 ENSG00000197429 ENSG00000167508 ENSG00000116984 PMC7718402__F6 Neutrophil signaling during resolution of inflammation ENSG00000168040 ENSG00000026103 PMC6857915__F8 Gene expression microarray public dataset reanalysis in chronic obstructive pulmonary disease ENSG00000133961 PMC9530352__F1 Glucose metabolism and glycosylation link the gut microbiota to autoimmune diseases ENSG00000172936 ENSG00000276561 PMC11947922__F1 Novel mechanism targeting Beta-arrestin-2 for the management of diabetic nephropathy ENSG00000128272 ENSG00000100219 PMC6775696__F11 Interactions between MKI67 and eight genes related to P53 signaling pathway ENSG00000148773 ENSG00000134057 ENSG00000171848 ENSG00000075218 ENSG00000149554 ENSG00000064012 ENSG00000183765 PMC6357032__F2 Classification of caspases ENSG00000171791 PMC8688805__F2 Long Non-Coding RNAs, Novel Offenders or Guardians in Multiple Sclerosis: A Scoping Review ENSG00000141232 ENSG00000168209 ENSG00000138378 ENSG00000111537 ENSG00000198793 ENSG00000026508 ENSG00000118971 ENSG00000168610 ENSG00000146648 PMC8493876__F1 Targeting the CD27-CD70 Pathway to Improve Outcomes in Both Checkpoint Immunotherapy and Allogeneic Hematopoietic Cell Transplantation ENSG00000139193 ENSG00000089692 ENSG00000197635 PMC9705325__F7 Proposed antitumorigenic mechanism of CPX on GC growth ENSG00000291971 ENSG00000135446 ENSG00000145321 ENSG00000168610 PMC8492608__F12 Pathological Features of Tumors of the Nervous System in Hereditary Cancer Predisposition Syndromes: A Review ENSG00000134086 ENSG00000026508 ENSG00000133961 ENSG00000177084 ENSG00000128602 PMC6829226__F4 LncRNAs regulate EMT signaling pathways ENSG00000169554 ENSG00000124216 ENSG00000134982 ENSG00000019549 ENSG00000168036 PMC6033660__F2 Schematics of classical CSR from IgM to IgA ENSG00000164879 ENSG00000186716 PMC7761714__F2 The NRF2 signaling pathway by microRNAs (miRNAs) in cancers ENSG00000122378 ENSG00000178573 ENSG00000196591 ENSG00000096717 ENSG00000156273 ENSG00000079999 PMC9540245__F6 Identification of functional TF-miRNA-hub gene regulatory network associated with ovarian endometriosis ENSG00000159399 PMC10625490__F2 HIV infection induces intestinal mucosal barrier damage and immune cell dysfunction, which aggravates the inflammatory response ENSG00000111537 ENSG00000136869 PMC6901542__F6 Vitamin D promotes the cisplatin sensitivity of oral squamous cell carcinoma by inhibiting LCN2-modulated NFKB pathway activation through RPS3 ENSG00000148346 ENSG00000205221 ENSG00000149273 PMC4486656__F2 Fueling Immunity: Insights into Metabolism and Lymphocyte Function ENSG00000092621 ENSG00000115419 PMC11820997__F3 Beneficial effects of hydroxytyrosol (HTyr) on insulin signaling through the enhancement of insulin signaling pathways ENSG00000125538 PMC8858030__F3 Mass spectrometry imaging reveals substrate channeling by the purinosome, a liquid-like multi-enzyme assembly ENSG00000128050 PMC5882318__F1 Analysis of the PI3K-AKT-mTOR pathway in penile cancer: evaluation of a therapeutically targetable pathway ENSG00000005882 ENSG00000198793 PMC4276889__F6 Reduced HIF-1A expression in TRPM2-S-expressing cells determined by proteomic analysis ENSG00000181163 ENSG00000072274 ENSG00000170606 PMC6568224__F1 Necroptosis signaling pathwayNecroptosis can be caused by a variety of stimuli, including the ligands of the death receptor, TLRs, IFN receptors, and certain pathogens ENSG00000137275 ENSG00000102871 ENSG00000136869 ENSG00000083799 ENSG00000168404 ENSG00000127191 ENSG00000064012 ENSG00000164305 ENSG00000285379 ENSG00000164342 PMC8761731__F11 Predicting 3D Structure, Cross Talks, and Prognostic Significance of KLF9 in Cervical Cancer ENSG00000119138 ENSG00000082175 ENSG00000076554 ENSG00000163914 ENSG00000168610 PMC3890408__F2 Cooperating mutational events in MYC-driven lymphomagenesis and novel therapeutic opportunities.Notes: Continuous MYC expression is required for BL cell survival, as demonstrated by the apoptotic effect of the MYC inhibitor 10058-F4 on BL cell lines ENSG00000186716 ENSG00000105810 ENSG00000283060 ENSG00000104081 ENSG00000198625 PMC7338604__F1 Wnt/Beta-catenin signaling pathway ENSG00000134982 ENSG00000168036 PMC7338604__F2 Natural products targeting the Beta-catenin signaling pathway for cancer therapy ENSG00000168036 ENSG00000118898 PMC3653932__F7 TLR4 Activates the Beta-catenin Pathway to Cause Intestinal Neoplasia ENSG00000134982 ENSG00000172936 ENSG00000136869 PMC8651556__F1 Endothelial Dysfunction and Hyperhomocysteinemia-Linked Cerebral Small Vessel Disease: Underlying Mechanisms and Treatment Timing PMC2679751__F7 Proposed model for functional interaction between Ncs-1a, Pi4kB, and Arf1 in trafficking and secretion ENSG00000143393 ENSG00000143761 ENSG00000107130 PMC9549509__F6 Therapeutic hypothermia alleviates myocardial ischaemia–reperfusion injury by inhibiting inflammation and fibrosis via the mediation of the SIRT3/NLRP3 signalling pathway ENSG00000162711 ENSG00000125538 ENSG00000142082 PMC10375321__F1 One-carbon metabolism comprising the transmethylation pathway, nucleotide synthesis pathway, transsulfuration pathway and remethylation pathway ENSG00000228716 ENSG00000065911 ENSG00000100714 ENSG00000136371 PMC3810143__F9 Downregulation of Nuclear-Encoded Genes of Oxidative Metabolism in Dialyzed Chronic Kidney Disease Patients ENSG00000100811 ENSG00000106459 PMC11084272__F7 Action of multifunctional FYD in preventing cancer metastasis ENSG00000087245 ENSG00000170558 ENSG00000168036 ENSG00000162692 PMC5120123__F2 Positive regulatory signaling for Tfh differentiation ENSG00000183734 ENSG00000183735 ENSG00000111537 ENSG00000078747 ENSG00000150907 ENSG00000127528 ENSG00000168610 ENSG00000141968 PMC5387898__F2 Simplified schematic of the possible mechanism of lymphangiogenesis in cancer cell metastasis ENSG00000164690 ENSG00000138080 ENSG00000150630 PMC4439078__F5 Longitudinal Transcriptomic Response of the Substantia Nigra to Intrastriatal 6-Hydroxydopamine Reveals Significant Upregulation of Regeneration-Associated Genes ENSG00000065911 ENSG00000105329 ENSG00000140044 ENSG00000162772 ENSG00000049768 ENSG00000112038 ENSG00000245848 ENSG00000213949 ENSG00000172216 ENSG00000148773 ENSG00000196182 ENSG00000123342 ENSG00000092067 ENSG00000006327 ENSG00000135116 ENSG00000144655 ENSG00000095794 ENSG00000114346 ENSG00000176887 ENSG00000184661 ENSG00000221869 ENSG00000116717 ENSG00000172183 ENSG00000101255 ENSG00000112984 ENSG00000163794 ENSG00000174059 PMC7216437__F3 ATM functions in DNA damage repair pathway ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000083093 ENSG00000051180 ENSG00000149554 ENSG00000138385 ENSG00000139618 ENSG00000183765 PMC2643928__F1 Activation of the transcription factors IRF3 and NFKB in response to infection with a single-stranded RNA virus ENSG00000088888 ENSG00000131323 ENSG00000168040 ENSG00000064012 PMC7900405__F6 Schematic illustrating entosis and the actin machinery ENSG00000070831 ENSG00000169851 PMC3418847__F6 Interaction Map for PTMScan Direct: Akt/PI3K pathway reagent ENSG00000106682 ENSG00000142627 ENSG00000002330 ENSG00000109320 ENSG00000198561 ENSG00000198793 ENSG00000169047 ENSG00000164327 ENSG00000105647 ENSG00000121879 ENSG00000175054 ENSG00000117020 ENSG00000107338 ENSG00000141503 ENSG00000143393 ENSG00000010810 ENSG00000150907 ENSG00000088247 ENSG00000105723 ENSG00000164916 PMC3109507__F1 Choosing the right path: does DNA-PK help make the decision? ENSG00000012048 ENSG00000083093 ENSG00000039650 ENSG00000197299 ENSG00000051180 ENSG00000139618 PMC8134690__F1 HIV Nef-mediated Ubiquitination of BCL2: Implications in Autophagy and Apoptosis ENSG00000110497 ENSG00000108395 ENSG00000213186 ENSG00000171791 ENSG00000175104 ENSG00000130726 PMC7525032__F6 Scheme of the proposed lung IIR against S ENSG00000163739 ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC3162038__F2 Biosynthetic pathway to validamycin A and characterization of VldB, VldE, and VldH ENSG00000291814 PMC7940683__F1 Siglec-G in sepsis ENSG00000291971 ENSG00000272398 ENSG00000136869 ENSG00000168610 PMC7940683__F2 Siglec-G in various immune cells ENSG00000105492 ENSG00000088888 ENSG00000110395 ENSG00000186716 ENSG00000272398 ENSG00000189403 ENSG00000136869 ENSG00000107201 ENSG00000168610 ENSG00000131196 PMC6433784__F1 Mechanism of Action of FSH on Adipocytes PMC7387981__F1 Cannabinoids' pharmacology ENSG00000163914 ENSG00000168036 ENSG00000119912 PMC10478283__F8 Mechanism diagram ENSG00000178860 ENSG00000182742 ENSG00000204531 ENSG00000121966 PMC6827009__F6 Activation of CREM signaling pathway in spermatozoa of idiopathic infertile patients post-antioxidant treatment ENSG00000132693 PMC4510718__F2 Survivin (SVN) pathways to apoptosis ENSG00000084774 ENSG00000026103 PMC10530547__F3 Transcription Factor Zbtb20 as a Regulator of Malignancy and Its Practical Applications ENSG00000087245 ENSG00000168036 ENSG00000100985 ENSG00000081051 ENSG00000146648 ENSG00000132170 PMC4361590__F7 Repulsive Axon Guidance by Draxin Is Mediated by Protein Kinase B (Akt), Glycogen Synthase Kinase-3B (GSK-3B) and Microtubule-Associated Protein 1B ENSG00000162490 PMC6396335__F1 Assembly of the interferon (IFN)G receptor (IFNGR) and activation of Janus kinase (JAK)-signal transducers and activators of transcription (STAT) signaling ENSG00000159128 ENSG00000115415 ENSG00000033800 ENSG00000027697 PMC8103423__F4 Cell biology of Parkinson’s disease ENSG00000162711 ENSG00000089692 ENSG00000135218 ENSG00000010810 ENSG00000125538 ENSG00000158828 ENSG00000122194 PMC9572491__F1 Mini Review on Molecules Inducing Caspase-Independent Cell Death: A New Route to Cancer Therapy ENSG00000171791 ENSG00000026103 PMC3491806__F2 Inflammatory Bowel Disease ENSG00000112486 PMC4562633__F3 Discovery of Intermediary Genes between Pathways Using Sparse Regression ENSG00000104856 ENSG00000230034 ENSG00000111737 ENSG00000173578 ENSG00000084733 ENSG00000130513 ENSG00000135604 ENSG00000120705 ENSG00000197774 ENSG00000197632 ENSG00000136379 ENSG00000144228 ENSG00000167447 ENSG00000108465 ENSG00000231925 ENSG00000170425 ENSG00000106100 ENSG00000132842 ENSG00000073756 ENSG00000150712 ENSG00000013583 ENSG00000156675 ENSG00000166128 ENSG00000166801 ENSG00000113384 ENSG00000115956 ENSG00000111331 ENSG00000184216 PMC4562633__F4 Discovery of Intermediary Genes between Pathways Using Sparse Regression ENSG00000158411 ENSG00000169248 ENSG00000097033 ENSG00000138600 ENSG00000167207 ENSG00000030582 ENSG00000187608 ENSG00000101000 ENSG00000232326 ENSG00000069956 ENSG00000008083 ENSG00000111737 ENSG00000135899 ENSG00000118508 ENSG00000134321 ENSG00000108679 ENSG00000066027 ENSG00000119655 ENSG00000196182 ENSG00000084733 ENSG00000064012 ENSG00000148346 ENSG00000078668 ENSG00000196954 ENSG00000273686 ENSG00000231925 ENSG00000106100 ENSG00000132842 ENSG00000177542 ENSG00000111602 ENSG00000173221 ENSG00000206190 ENSG00000131748 ENSG00000008516 ENSG00000001561 ENSG00000125844 ENSG00000080371 ENSG00000123609 ENSG00000059378 ENSG00000274183 ENSG00000164054 ENSG00000169902 ENSG00000164953 ENSG00000213512 ENSG00000116977 ENSG00000101421 ENSG00000155363 ENSG00000111224 PMC11747344__F6 Investigation of Scutellaria Barbata’s immunological mechanism against thyroid cancer using network pharmacology and experimental validation ENSG00000047410 ENSG00000002330 ENSG00000157764 ENSG00000105401 ENSG00000198793 ENSG00000169047 ENSG00000168036 ENSG00000197601 ENSG00000177455 ENSG00000103479 ENSG00000186716 ENSG00000198125 ENSG00000122008 PMC3118418__F1 Which FGF ligands are involved in lens induction? ENSG00000138083 ENSG00000117707 PMC4930925__F4 Gene circuits for biomedical applications ENSG00000105699 ENSG00000113749 ENSG00000168610 PMC4750973__F5 Identification of Targets of CUG-BP, Elav-Like Family Member 1 (CELF1) Regulation in Embryonic Heart Muscle ENSG00000291931 ENSG00000084093 ENSG00000163435 ENSG00000198755 ENSG00000071082 ENSG00000137818 ENSG00000147604 ENSG00000105656 ENSG00000188846 ENSG00000136942 PMC9181451__F3 Molecular Glues: Capable Protein-Binding Small Molecules That Can Change Protein–Protein Interactions and Interactomes for the Potential Treatment of Human Cancer and Neurodegenerative Diseases ENSG00000288453 ENSG00000100461 PMC9181451__F4 Molecular Glues: Capable Protein-Binding Small Molecules That Can Change Protein–Protein Interactions and Interactomes for the Potential Treatment of Human Cancer and Neurodegenerative Diseases ENSG00000167258 ENSG00000100387 ENSG00000167986 PMC5142754__F1 Targeting Inflammation in Cancer Prevention and Therapy ENSG00000108691 ENSG00000168610 PMC5142754__F2 Targeting Inflammation in Cancer Prevention and Therapy ENSG00000136869 PMC9181451__F1 Molecular Glues: Capable Protein-Binding Small Molecules That Can Change Protein–Protein Interactions and Interactomes for the Potential Treatment of Human Cancer and Neurodegenerative Diseases ENSG00000167986 ENSG00000113851 PMC12025505__F2 Signaling Mechanism of Budding, Proliferation, and Tissue Regeneration in Cnidaria ENSG00000134982 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC8579452__F3 IL-1B in atherosclerotic vascular calcification: From bench to bedside ENSG00000162711 ENSG00000281324 ENSG00000130164 ENSG00000162337 ENSG00000125538 PMC8035348__F3 Non-coding RNA biomarkers in pancreatic ductal adenocarcinoma ENSG00000134982 ENSG00000168036 ENSG00000173702 ENSG00000124782 PMC8035348__F4 Non-coding RNA biomarkers in pancreatic ductal adenocarcinoma ENSG00000105894 ENSG00000179241 ENSG00000078399 ENSG00000135506 PMC5799771__F7 CK1Alpha-, 26 S proteasome-dependent turnover of FOXO tumour suppressors in RAS-mutant cancer cells ENSG00000198793 ENSG00000184481 ENSG00000106459 PMC7755484__F7 Proposed mechanism of AS-IV-induced melanogenesis ENSG00000168036 ENSG00000107165 ENSG00000106546 PMC3500781__F1 Two different pathways could bypass DNA damage causing stalled replication forks ENSG00000132646 ENSG00000070950 PMC7288008__F3 Pathophysiology of Ulcerative Colitis ENSG00000169245 ENSG00000163739 ENSG00000137265 ENSG00000163734 ENSG00000107485 ENSG00000169429 ENSG00000049768 PMC9315664__F4 Advances in Crosstalk between Porcine Circoviruses and Host ENSG00000094631 ENSG00000102753 ENSG00000185187 ENSG00000127191 ENSG00000168610 ENSG00000276561 ENSG00000168259 ENSG00000164430 ENSG00000088888 ENSG00000144895 ENSG00000125538 ENSG00000172936 ENSG00000185591 PMC4445694__F1 Marketed nonsteroidal anti-inflammatory agents, antihypertensives, and human immunodeficiency virus protease inhibitors: as-yet-unused weapons of the oncologists’ arsenal ENSG00000185591 ENSG00000168610 PMC7723564__F7 Primary mechanism of PRP improves chronic inflammatory pain ENSG00000189403 ENSG00000131095 ENSG00000168610 PMC6616296__F10 Proposed mechanism of the p75NTR as a mediator of synaptic changes during SD PMC4219936__F2 Bile acid signaling in lipid metabolism: Metabolomic and lipidomic analysis of lipid and bile acid markers linked to anti-obesity and anti-diabetes in mice ENSG00000063176 ENSG00000167910 ENSG00000125538 ENSG00000136869 ENSG00000267534 PMC4537170__F1 Mammalian base excision repair and single-strand break repair pathways ENSG00000105486 ENSG00000132646 ENSG00000039650 ENSG00000140398 ENSG00000177084 PMC4219936__F1 Bile acid signaling in lipid metabolism: Metabolomic and lipidomic analysis of lipid and bile acid markers linked to anti-obesity and anti-diabetes in mice ENSG00000167910 ENSG00000180432 PMC10418722__F12 Study on the Regulation Mechanism of Quality Deterioration Due to Chilling Stress and Dry Exposure during Anhydrous Storage and Transportation of Yesso Scallop Patinopecten yessoensis ENSG00000142192 ENSG00000177606 ENSG00000254550 PMC5780146__F5 Differentially expressed genes (red) in the neonatal respiratory distress syndrome group compared with the control group in the TNF signaling pathway ENSG00000185015 ENSG00000167207 ENSG00000170369 ENSG00000078747 ENSG00000007908 ENSG00000131323 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000164305 PMC5780146__F6 Differentially expressed genes (red) in the neonatal respiratory distress syndrome group compared with the control group in the influenza A pathway ENSG00000132906 ENSG00000213928 ENSG00000111537 ENSG00000226492 ENSG00000160710 ENSG00000140464 PMC8913936__F3 Proteomic Analysis Reveals a Novel Therapeutic Strategy Using Fludarabine for Steroid-Resistant Asthma Exacerbation ENSG00000105397 ENSG00000115415 ENSG00000232326 ENSG00000127022 ENSG00000273686 ENSG00000231925 PMC4461786__F4 Noncanonical Wnt5a signalling: a simplified view ENSG00000169071 PMC3611005__F10 LKB1-SIK2/3-class IIa HDAC pathway as a novel signaling module ENSG00000160584 ENSG00000061273 ENSG00000170145 ENSG00000160741 ENSG00000108840 PMC7864190__F2 Latent TGFB activation and the canonical TGFB signaling pathway PMC8814522__F4 Do Genetic Polymorphisms Affect Fetal Hemoglobin (HbF) Levels in Patients With Sickle Cell Anemia Treated With Hydroxyurea? A Systematic Review and Pathway Analysis ENSG00000081181 ENSG00000105610 ENSG00000118520 PMC8167679__F1 Iron homeostasis and iron-mediated ROS in cancer ENSG00000151012 ENSG00000168610 PMC8097341__F2 Various mechanisms underlying targeting of de novo DNMTs by histone methylation ENSG00000142182 ENSG00000088305 ENSG00000109685 ENSG00000181555 PMC4632302__F9 Diagram of signaling pathway for genistein-induced apoptosis in Bax and p53-independent manner ENSG00000132906 ENSG00000120868 ENSG00000164305 PMC8841732__F10 All-Trans Retinoic Acid Attenuates Transmissible Gastroenteritis Virus-Induced Inflammation in IPEC-J2 Cells via Suppressing the RLRs/NF‐KB Signaling Pathway ENSG00000088888 ENSG00000125538 ENSG00000175104 PMC10980521__F7 Main pathways of reproductive candidate genes for follicular growth and ovulation in Tibetan sheep ENSG00000170365 ENSG00000115457 ENSG00000138039 ENSG00000174136 ENSG00000087460 ENSG00000204217 ENSG00000140443 PMC7993417__F4 Phenotypic diversity and metabolic specialization of renal endothelial cells ENSG00000213658 ENSG00000142082 ENSG00000026103 PMC7993417__F5 Phenotypic diversity and metabolic specialization of renal endothelial cells ENSG00000170961 ENSG00000086991 ENSG00000127528 ENSG00000198670 ENSG00000096717 ENSG00000136826 PMC3769322__F3 Regulation of action cytoskeleton in LTLT-Ca MCF-7 cells ENSG00000120063 ENSG00000170458 ENSG00000010810 ENSG00000163914 PMC12179639__F1 Scientific diagram illustrating the mechanism of FGFR1 signaling, showing key pathways like PI3K-Akt-mTOR and RAS-RAF-MEK-MAPK for cell survival and proliferation ENSG00000198793 ENSG00000177606 ENSG00000077782 PMC1855985__F1 Mutational Analysis of EGFR and Related Signaling Pathway Genes in Lung Adenocarcinomas Identifies a Novel Somatic Kinase Domain Mutation in FGFR4 ENSG00000157764 ENSG00000065361 ENSG00000065559 ENSG00000108443 ENSG00000069956 ENSG00000166484 ENSG00000175634 ENSG00000066468 ENSG00000185386 ENSG00000160867 ENSG00000188130 ENSG00000146648 ENSG00000178568 PMC6362409__F1 Microbiota and the intestinal barrier against infectious threats ENSG00000111537 ENSG00000187554 ENSG00000136869 PMC12179639__F2 Interactions between the PD-1/programmed death-ligand 1 (PD-L1), fibroblast growth factor receptor 1 (FGFR1) pathways, and chemokines ENSG00000169245 ENSG00000111537 ENSG00000069869 ENSG00000077782 PMC9581278__F9 Poria cocos extract on metabolic dysfunction-associated fatty liver disease via the FXR/PPARAlpha-SREBPs pathway ENSG00000042832 ENSG00000160867 ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC8517756__F2 Endothelial dysfunction and COVID-19 (Review) ENSG00000130234 PMC6551999__F5 A Review of Hydrogen Sulfide Synthesis, Metabolism, and Measurement: Is Modulation of Hydrogen Sulfide a Novel Therapeutic for Cancer? ENSG00000179091 ENSG00000168610 PMC7343815__F4 Autophagy as a modulator of cell death machinery ENSG00000057663 PMC6551999__F1 A Review of Hydrogen Sulfide Synthesis, Metabolism, and Measurement: Is Modulation of Hydrogen Sulfide a Novel Therapeutic for Cancer? PMC2821201__F6 A diagrammatic model to summarize the role and subcellular localization of survivin and its splice variants in the regulation of apoptosis and control of mitosis in cancer cells ENSG00000117399 ENSG00000149503 PMC10559578__F2 Production of IL-1B and its transduction signaling pathway ENSG00000278718 ENSG00000162711 ENSG00000172936 ENSG00000265972 ENSG00000175104 ENSG00000184216 PMC3491906__F1 Distinct signaling pathways of synaptic and extrasynaptic NMDAR in neuron fate ENSG00000170145 ENSG00000265972 ENSG00000162772 PMC11846447__F4 Muscle protein regulation through the mTOR pathway ENSG00000169047 ENSG00000198793 PMC12191313__F3 Molecular Mechanisms of Epithelial–Mesenchymal Transition in Retinal Pigment Epithelial Cells: Implications for Age-Related Macular Degeneration (AMD) Progression ENSG00000134982 ENSG00000168036 PMC3528293__F1 Generalized overview of the extrinsic and intrinsic apoptosis pathways ENSG00000102871 ENSG00000168040 PMC11171594__F1 TLR-mediated signaling ENSG00000174123 ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC6705839__F3 System analysis of cross-talk between nuclear receptors reveals an opposite regulation of the cell cycle by LXR and FXR in human HepaRG liver cells ENSG00000108055 ENSG00000205250 ENSG00000277273 ENSG00000166851 ENSG00000117399 ENSG00000276876 ENSG00000093009 ENSG00000145604 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000164754 PMC8671568__F1 Neuroadaptations and TGFB Signaling: Emerging role in models of neuropsychiatric disorders ENSG00000121989 ENSG00000170365 ENSG00000198742 ENSG00000168036 ENSG00000113758 ENSG00000291761 ENSG00000112186 PMC7495088__F9 PIgR regulation in CF lung ENSG00000001626 ENSG00000112115 ENSG00000162896 PMC3865699__F1 Major mechanisms linking obesity with impaired muscle regeneration ENSG00000132646 ENSG00000125538 ENSG00000198793 PMC4841026__F5 Infant birth weight and third trimester maternal plasma markers of vascular integrity: the MIREC study ENSG00000125735 ENSG00000000971 ENSG00000168036 ENSG00000168615 ENSG00000107175 ENSG00000134574 ENSG00000177606 ENSG00000167468 ENSG00000088247 ENSG00000136160 ENSG00000156860 ENSG00000137843 ENSG00000132517 ENSG00000105825 PMC3500394__F1 FoxM1 and WntBeta-catenin Signaling in Glioma Stem Cells ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC5794818__F2 T cell activation induces autocrine and intracellular complement activation that regulates T cell metabolic function and inflammasome formation ENSG00000162711 ENSG00000198793 ENSG00000105656 ENSG00000117335 ENSG00000049768 PMC8075059__F3 Back to the Future: From Appendage Development Toward Future Human Hair Follicle Neogenesis ENSG00000135960 PMC8424978__F7 Bufalin suppresses tumour microenvironment-mediated angiogenesis by inhibiting the STAT3 signalling pathway ENSG00000007908 ENSG00000168610 PMC5856858__F1 KEGG Apoptosis pathway with highlighted dysregulated mRNAs and miRNAs ENSG00000110711 ENSG00000065833 ENSG00000128272 ENSG00000002330 ENSG00000102871 ENSG00000087842 ENSG00000168040 ENSG00000127191 ENSG00000135116 ENSG00000084774 ENSG00000115317 PMC4727405__F8 Alternative NOTCH pathway representations ENSG00000181163 ENSG00000128917 ENSG00000196498 ENSG00000150457 ENSG00000133961 ENSG00000177425 PMC5541362__F2 Serotonin and serotonin transporters in the adrenal medulla: a potential hub for modulation of the sympathetic stress response PMC4727405__F4 Screenshot of CNV and splicing representation ENSG00000002330 ENSG00000198793 PMC5797067__F1 Exon 3 mutations of CTNNB1 drive tumorigenesis: a review ENSG00000134982 ENSG00000167074 ENSG00000168646 PMC6754810__F1 Activators and suppressors of OCT4 in cancer stem cells ENSG00000079387 ENSG00000134982 ENSG00000168036 ENSG00000150630 PMC9310348__F1 Apoptosis regulation through protein–protein interactions ENSG00000100290 ENSG00000002330 ENSG00000120868 ENSG00000168040 ENSG00000135116 ENSG00000104081 ENSG00000026103 PMC6830904__F1 Intracellular NAD metabolism ENSG00000105835 ENSG00000123572 ENSG00000157064 ENSG00000173614 ENSG00000138356 PMC10915323__F1 Leveraging molecular targeted drugs and immune checkpoint inhibitors treat advanced thyroid carcinoma to achieve thyroid carcinoma redifferentiation ENSG00000122025 ENSG00000019991 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC7750537__F6 Crosstalk between the coagulation cascade and autophagy on tumor-associated endothelial cells ENSG00000126775 ENSG00000150907 PMC7750537__F7 Crosstalk between coagulation and autophagy promotes cancer-associated thrombosis and metastasis ENSG00000163235 PMC3688827__F6 Transcriptome Analysis Reveals Novel Entry Mechanisms and a Central Role of SRC in Host Defense during High Multiplicity Mycobacterial Infection ENSG00000105993 ENSG00000162711 ENSG00000102753 ENSG00000105329 ENSG00000109320 ENSG00000291971 ENSG00000103222 ENSG00000168036 ENSG00000162924 ENSG00000124762 ENSG00000106546 ENSG00000137801 ENSG00000135924 ENSG00000011422 ENSG00000136997 ENSG00000125538 ENSG00000026103 PMC7750537__F1 Coagulation and clotting factor signaling ENSG00000003436 ENSG00000134982 ENSG00000122194 PMC8350333__F8 Cross-talk among MEN1, p53 and Notch regulates the proliferation of pancreatic neuroendocrine tumor cells by modulating INSM1 expression and subcellular localization ENSG00000133895 ENSG00000173404 ENSG00000114315 PMC7750537__F2 Autophagic pathway ENSG00000152348 ENSG00000123395 ENSG00000126775 ENSG00000110799 ENSG00000144848 ENSG00000171791 ENSG00000145782 ENSG00000057663 ENSG00000142224 PMC7750537__F5 Crosstalk of the coagulation cascade and autophagy pathway in cancer cells ENSG00000125538 ENSG00000145782 PMC7567008__F3 Crosstalk between Toll-like-receptor (TLR) signaling and the Hippo pathway in Drosophila and mammalian cells ENSG00000183735 ENSG00000172936 ENSG00000131323 ENSG00000130159 ENSG00000175104 PMC4338943__F1 Retinoid signaling (RA) signaling pathway ENSG00000095596 ENSG00000187553 ENSG00000184254 ENSG00000121207 ENSG00000138207 ENSG00000284807 ENSG00000003137 ENSG00000121039 ENSG00000128918 ENSG00000118514 ENSG00000143320 ENSG00000073737 PMC8076900__F1 Control of T Cell Metabolism by Cytokines and Hormones ENSG00000198793 ENSG00000103522 ENSG00000103257 ENSG00000168685 PMC5056151__F2 Transport proteins in Alzheimer’s disease ENSG00000103222 ENSG00000118777 PMC10216079__F3 Main signaling pathway in rheumatoid arthritis ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC5666796__F9 Schematic model of possible signalling events involved in the upregulation of TGFB1 expression by LTBP-2 ENSG00000180210 ENSG00000117525 ENSG00000119681 PMC4253516__F7 Transforming growth factorB (TGFB) and the canonical Smad pathway negatively regulate CD1d-mediated antigen presentation PMC6130320__F4 MIF family cytokines in cardiovascular diseases and prospects for precision-based therapeutics ENSG00000019582 ENSG00000026508 PMC3830618__F2 Homeostatic plasticity at the Drosophila neuromuscular junction ENSG00000070831 ENSG00000132639 PMC12010972__F4 Targeted therapy for osteoporosis ENSG00000156076 ENSG00000281324 ENSG00000162337 ENSG00000167941 ENSG00000168036 PMC12010972__F2 Inhibition of Wnt/Beta-catenin signaling pathway by Wnt signaling pathway inhibitors ENSG00000156076 ENSG00000162337 ENSG00000167941 PMC12010972__F3 Wnt signaling pathway inhibitors ENSG00000156076 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000168036 PMC12010972__F1 Regulatory mechanisms of the Wnt signaling pathway ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000177606 ENSG00000168036 PMC7567008__F1 Tumor-cell-intrinsic roles of Yap/Taz in regulating tumor immunity ENSG00000150457 ENSG00000131023 PMC7471657__F3 Gene ontology terms and KEGG pathways ENSG00000081237 ENSG00000198851 ENSG00000156738 ENSG00000129226 ENSG00000263057 ENSG00000049768 ENSG00000188389 PMC9751411__F2 Interferon and interferon-stimulated genes in HBV treatment ENSG00000213928 ENSG00000115415 ENSG00000142166 PMC5591558__F3 EGFR cell signaling and lncRNAs relationship in lung cancer therapy resistance ENSG00000169047 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC4649479__F1 Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei ENSG00000173599 PMC8835863__F1 Apoptosis during ZIKA Virus Infection: Too Soon or Too Late? ENSG00000128272 ENSG00000100219 ENSG00000168040 PMC5698512__F1 IL-6 signaling pathways ENSG00000198793 PMC9453844__F6 Identification of potential miRNA-mRNA regulatory network and the key miRNAs in intramuscular and subcutaneous adipose ENSG00000175592 ENSG00000169884 ENSG00000002745 ENSG00000134245 ENSG00000012211 ENSG00000146374 PMC11594159__F1 Redrawn from WSP268, the version of the Notch signaling pathway depicted on Wikipedia https://www ENSG00000004975 ENSG00000196591 ENSG00000196782 ENSG00000143801 ENSG00000138613 ENSG00000163840 ENSG00000074181 ENSG00000128917 ENSG00000283780 ENSG00000196498 ENSG00000107404 ENSG00000005339 ENSG00000148400 ENSG00000100060 ENSG00000178498 ENSG00000184916 ENSG00000175029 ENSG00000135144 ENSG00000090932 ENSG00000110042 ENSG00000106003 ENSG00000091073 ENSG00000273529 ENSG00000133961 ENSG00000161202 ENSG00000114315 PMC122866__F4 The pathway of PUFA synthesis in C ENSG00000083857 ENSG00000165323 PMC6770240__F1 Overview of an acute myeloid leukemia cell’s metabolism ENSG00000115419 PMC7552539__F5 Simplified examples of the roles that different classes of ceRNAs play in HCC oncogenesis ENSG00000124422 ENSG00000096717 ENSG00000153317 PMC2905036__F3 Schematic diagram depicting the molecular mechanisms by which inflammation activates hepcidin transcription in the liver ENSG00000170365 ENSG00000168610 PMC2905036__F2 Schematic diagram depicting the proposed role of bone morphogenetic protein (BMP) signaling pathway, HJV, HFE, and TFR2 in iron sensing and hepcidin regulation in the liver ENSG00000170365 ENSG00000010704 ENSG00000106327 ENSG00000187045 PMC8532063__F1 Current Diagnosis and Management of Primary Chylomicronemia ENSG00000103227 ENSG00000277494 PMC11641621__F3 Schematics describing the role of particular small-molecule protein kinases and their inhibitors in PAH microenvironment, including such molecular hallmarks as inflammation, apoptosis, proliferation, or mitochondrial function ENSG00000122025 ENSG00000162733 ENSG00000198793 ENSG00000146648 PMC3334602__F7 Cordycepin analogues and the C ENSG00000156110 ENSG00000196839 ENSG00000291814 PMC5036407__F6 Illustration showing the mechanism by which NDRG1 mediates activation of the Wnt signaling pathway ENSG00000065717 ENSG00000134982 ENSG00000168036 PMC5609400__F3 The Shh, TGFB/BMP, and Wnt morphogenic signaling pathways ENSG00000281324 ENSG00000162337 ENSG00000100592 ENSG00000134982 ENSG00000163914 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC5029616__F1 Altered glucose metabolism in tumor and a tumor acidic microenvironment associated with extracellular matrix metalloproteinase inducer and monocarboxylate transporters ENSG00000087245 ENSG00000100985 PMC5029616__F2 Altered glucose metabolism in tumor and a tumor acidic microenvironment associated with extracellular matrix metalloproteinase inducer and monocarboxylate transporters ENSG00000185591 PMC3168677__F2 MicroRNAs in Rheumatoid Arthritis ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC9393262__F1 Th2A cells: The pathogenic players in allergic diseases ENSG00000291603 ENSG00000137033 ENSG00000134982 ENSG00000172936 ENSG00000175104 PMC9698307__F1 Emerging Direct Targeting Beta-Catenin Agents ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5773404__F2 Synaptically Localized Transcriptional Regulators in Memory Formation ENSG00000174576 ENSG00000198576 ENSG00000105662 PMC6895530__F6 Working model ENSG00000198793 ENSG00000171791 PMC8696218__F8 Emerging agents that target signaling pathways to eradicate colorectal cancer stem cells ENSG00000124216 ENSG00000122691 PMC8696218__F6 Emerging agents that target signaling pathways to eradicate colorectal cancer stem cells ENSG00000157184 PMC8696218__F7 Emerging agents that target signaling pathways to eradicate colorectal cancer stem cells ENSG00000198793 ENSG00000136997 ENSG00000146648 ENSG00000140443 PMC8696218__F4 Emerging agents that target signaling pathways to eradicate colorectal cancer stem cells ENSG00000104856 ENSG00000136997 ENSG00000164362 ENSG00000111321 ENSG00000100985 PMC4617547__F1 Summary of unfolded protein response and endoplasmic reticulum stress signaling pathways ENSG00000128272 ENSG00000158615 ENSG00000144895 ENSG00000177606 ENSG00000087074 ENSG00000100219 ENSG00000127191 ENSG00000168610 ENSG00000086232 PMC8696218__F5 Emerging agents that target signaling pathways to eradicate colorectal cancer stem cells ENSG00000087245 ENSG00000136997 ENSG00000168610 PMC2779759__F7 Schematic model illustrating how Jun proteins regulate the TIMP-3, TACE, and TNFA pathway: Jun proteins transcriptionally activate TIMP-3 expression, which is responsible for TACE inhibition ENSG00000100234 PMC8696218__F2 Emerging agents that target signaling pathways to eradicate colorectal cancer stem cells ENSG00000140564 ENSG00000125398 ENSG00000128917 ENSG00000136997 ENSG00000184916 ENSG00000090932 PMC8696218__F3 Emerging agents that target signaling pathways to eradicate colorectal cancer stem cells ENSG00000124216 ENSG00000134057 ENSG00000136997 ENSG00000128602 PMC2528859__F2 The UPR sensors PERK, IRE1A, and ATF6 control mRNA translation and transcriptional induction of UPR-regulated genes ENSG00000128272 ENSG00000144895 ENSG00000121351 PMC8696218__F1 Emerging agents that target signaling pathways to eradicate colorectal cancer stem cells ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000154310 PMC9495000__F6 Transcriptome Analyses Provide Insights into the Auditory Function in Trachemys scripta elegans ENSG00000183185 ENSG00000113327 ENSG00000111371 ENSG00000157542 PMC9520664__F1 V-Set and immunoglobulin domain containing (VSIG) proteins as emerging immune checkpoint targets for cancer immunotherapy ENSG00000162711 ENSG00000005882 ENSG00000155659 PMC8564058__F9 An ATX-LPA6-GA13-ROCK axis shapes and maintains caudal vein plexus in zebrafish ENSG00000168036 ENSG00000198670 PMC3310050__F12 Folate Decorated Dual Drug Loaded Nanoparticle: Role of Curcumin in Enhancing Therapeutic Potential of Nutlin-3a by Reversing Multidrug Resistance ENSG00000171791 PMC7249327__F6 At the top of the signalling pathway, the critical Arpp19 dephosphorylation at S109 by PP2A-B55D ENSG00000172680 ENSG00000128989 PMC5929433__F1 Ceramide species are elevated in human breast cancer and are associated with less aggressiveness ENSG00000100422 ENSG00000198964 ENSG00000128699 ENSG00000292130 ENSG00000164023 ENSG00000188611 ENSG00000070610 ENSG00000166224 ENSG00000172057 ENSG00000123353 ENSG00000148154 ENSG00000135587 PMC4162460__F8 Schematic for reprogramming of EBV-induced glucose metabolism ENSG00000136997 ENSG00000159399 PMC6441621__F1 miR-223 regulates the canonical NFKB pathway and other pathways related to cancer ENSG00000162711 ENSG00000204103 ENSG00000102908 ENSG00000115415 ENSG00000150907 ENSG00000172936 ENSG00000162924 ENSG00000175104 ENSG00000168610 ENSG00000081189 ENSG00000184216 ENSG00000140443 PMC8760138__F3 Chloroplast ROS and stress signaling ENSG00000066926 PMC2940478__F3 Web-accessible GnRHR pathway navigator ENSG00000084093 ENSG00000158825 PMC8698532__F2 Targeting Inflammasome Activation in COVID-19: Delivery of RNA Interference-Based Therapeutic Molecules ENSG00000162711 ENSG00000164056 ENSG00000136869 PMC11995514__F5 Core mechanism of necroptosis and related kinases affect the signaling pathway ENSG00000124256 ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC9326668__F1 Polyamines and Their Metabolism: From the Maintenance of Physiological Homeostasis to the Mediation of Disease ENSG00000168003 ENSG00000088826 ENSG00000175003 ENSG00000148832 ENSG00000112499 ENSG00000221955 ENSG00000146477 ENSG00000118520 ENSG00000133657 ENSG00000116649 ENSG00000102172 PMC11995514__F6 Core mechanism of ferroptosis and related kinases affect the signaling pathway ENSG00000162733 ENSG00000138449 ENSG00000151012 ENSG00000160867 ENSG00000291971 ENSG00000167468 ENSG00000168036 ENSG00000042286 ENSG00000142082 ENSG00000196628 PMC11995514__F3 Core mechanism of pyrotosis and related kinases affect the signaling pathway ENSG00000278718 ENSG00000162711 ENSG00000102871 ENSG00000091592 ENSG00000145649 ENSG00000168610 ENSG00000146648 ENSG00000147697 ENSG00000073605 PMC11995514__F4 Core mechanism of autophagy and related kinases affect the signaling pathway ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000144848 ENSG00000102010 ENSG00000166851 ENSG00000145782 ENSG00000168610 ENSG00000146648 ENSG00000057663 ENSG00000292210 PMC3519956__F6 Schematic model depicting how HMW isoforms regulate bone formation ENSG00000118972 ENSG00000077782 PMC11995514__F2 Core mechanism of apoptosis and related kinases affect the signaling pathway ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC5313453__F2 Figure illustrating five pathways putatively causing pathological remodelling in ACM: 1) Deficits in EB-1 ID protein trafficking provoke disturbance of the ID morphology ENSG00000168036 PMC3928173__F4 Epigenetic loss of the PIWI/piRNA machinery in human testicular tumorigenesis ENSG00000095627 ENSG00000275051 PMC4889278__F6 Upon tumor progression E-cadherin downregulation leads to an increase of the proportion of CSCs and acquisition of the ability to form secondary foci of tumor growth ENSG00000168036 PMC2729687__F2 Immunological synapse or the interface between an antigen presenting cell and a T-cell ENSG00000134982 ENSG00000163599 ENSG00000049768 PMC9563579__F1 Post-Translational Modifications of cGAS-STING: A Critical Switch for Immune Regulation PMC3185522__F3 HCV induces the over-expression of PP2Ac via an ER stress response pathway ENSG00000105397 ENSG00000115415 ENSG00000126457 PMC3865984__F1 Autophagy Pathway ENSG00000152348 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC3865984__F2 Molecular regulation of autophagy ENSG00000177169 ENSG00000123395 ENSG00000023287 ENSG00000198793 PMC9127500__F9 Antidepressants Fluoxetine Mediates Endoplasmic Reticulum Stress and Autophagy of Non–Small Cell Lung Cancer Cells Through the ATF4-AKT-mTOR Signaling Pathway ENSG00000128272 ENSG00000198793 ENSG00000123374 PMC11789495__F5 MTORC1 signaling pathway extensively controls cellular metabolism ENSG00000177169 ENSG00000065911 ENSG00000112561 ENSG00000135069 ENSG00000146733 ENSG00000120254 ENSG00000074800 ENSG00000128272 ENSG00000092621 ENSG00000159399 ENSG00000169299 ENSG00000164916 ENSG00000135250 ENSG00000084774 PMC5291092__F8 Toxic metabolites, MAPK and Nrf2/Keap1 signaling pathways involved in oxidative toxicity in mice liver after chronic exposure to Mequindox ENSG00000181019 ENSG00000079999 ENSG00000163631 PMC7364497__F2 Crosstalk between key signal pathways during prostatic budding ENSG00000168036 ENSG00000167034 PMC7272660__F5 Genes mapped to KEGG pathways by pathway analysis ENSG00000117400 ENSG00000134531 PMC4284387__F2 MiR-124 and miR-9/9* engage in complex regulatory circuits activating a neuronal gene expression program ENSG00000084093 ENSG00000011304 ENSG00000114315 PMC11617408__F6 Activin and BMP signaling pathway ENSG00000170365 PMC4107712__F1 Illustration of the PI3K/Akt/mTOR pathway ENSG00000155792 ENSG00000146648 PMC11617408__F5 Apoptosis: Tumor Necrosis Factor (TNF)-Related Apoptosis-Inducing Ligand (TRAIL) initiates cell death through two mechanisms: direct caspase activation or indirect activation via the release of apoptogenic factors from mitochondria ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC6073766__F1 Major downstream signaling pathway of mTORC1 and mTORC2 ENSG00000177169 ENSG00000065911 ENSG00000155792 ENSG00000112561 PMC7317437__F5 Proposed schematic diagram of signalling pathways for doxorubicin‐induced muscle atrophy ENSG00000169047 ENSG00000198793 PMC2701885__F2 Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence ENSG00000183735 ENSG00000105397 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC11214400__F6 Inflammatory loop involving Staphylococcus aureus, IL-36G, and cathepsin S drives immunity disorders in familial acne inversa keratinocytes ENSG00000111537 ENSG00000136826 PMC11549404__F9 Molecular mechanisms underlying FNDC4-mediated protection against cardiac I/R injury ENSG00000115226 PMC7393197__F3 Antitumour peptide based on a protein derived from the horseshoe crab: CIGB‐552 a promising candidate for cancer therapy ENSG00000132906 ENSG00000173163 ENSG00000144566 ENSG00000064012 ENSG00000164305 PMC2861543__F6 Differential role for endocytosis in receptor-dependent Nox1 generation of ROS and activation of cellular signalling ENSG00000146648 ENSG00000123268 PMC7649120__F6 Scheme of possible pathways by which liposomes can “hit” PIM cells via C activation; example for the case of PEGylated liposomal doxorubicin (Doxil) and other PEGylated NPs ENSG00000175054 ENSG00000203710 ENSG00000117322 PMC4583851__F5 The differentially expressed profiles ENSG00000095585 ENSG00000087095 ENSG00000226275 ENSG00000213658 ENSG00000102871 ENSG00000186716 ENSG00000131323 ENSG00000130159 ENSG00000175104 ENSG00000127191 ENSG00000026103 PMC8256842__F8 13-Gene Metabolic Prognostic Signature Is Associated With Clinical and Immune Features in Stomach Adenocarcinoma ENSG00000169291 ENSG00000128342 PMC8473087__F5 COVID-19: Mechanistic Model of the African Paradox Supports the Central Role of the NFKB Pathway ENSG00000169245 ENSG00000130234 ENSG00000184012 ENSG00000113520 ENSG00000136869 ENSG00000162692 ENSG00000276561 ENSG00000164342 PMC3588179__F2 T-cell immune regulation by IDO1 ENSG00000177455 PMC6831453__F1 Multiple immunosuppressive mechanisms coexist in tumor microenvironment ENSG00000163464 ENSG00000107562 ENSG00000262635 ENSG00000163739 ENSG00000198793 ENSG00000112715 ENSG00000121807 ENSG00000121966 ENSG00000106546 ENSG00000108691 ENSG00000239732 ENSG00000189403 ENSG00000136869 ENSG00000118520 ENSG00000164342 PMC3588179__F4 The mechanism of IDO1 regulation on viral infectious diseases ENSG00000198793 PMC4673281__F6 Analysis of the transcriptional regulation of cancer-related genes by aberrant DNA methylation of the cis-regulation sites in the promoter region during hepatocyte carcinogenesis caused by arsenic ENSG00000049323 ENSG00000087095 ENSG00000134982 ENSG00000156574 ENSG00000134363 ENSG00000137801 ENSG00000111537 ENSG00000095739 ENSG00000100387 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000164093 PMC11518755__F1 Molecular alterations of RAI-RTCs ENSG00000157764 ENSG00000198793 ENSG00000189079 PMC8070110__F2 Schematic diagram of the interconnection between EMT and TRF1/2 ENSG00000087245 ENSG00000122691 ENSG00000170558 ENSG00000164362 ENSG00000128513 PMC11518755__F2 NIS expression ENSG00000125482 ENSG00000165409 PMC4516463__F1 Signalling pathways involved in skeletal muscle remodelling and atrophy following disuse ENSG00000169047 ENSG00000198793 ENSG00000166278 PMC8848474__F1 Antitumor activity of the dual PI3K/mTOR inhibitor gedatolisib and the involvement of ABCB1 in gedatolisib resistance in canine tumor cells PMC3811055__F2 mTOR pathway ENSG00000134982 ENSG00000198793 PMC3594971__F3 c-jun N-terminal kinase (JNK) pathway in postmitotic migrating neurons ENSG00000077279 PMC11989508__F3 In PD, the molecular mechanism of ERS involves the interaction of multiple factors ENSG00000161682 ENSG00000144895 ENSG00000137801 PMC11989508__F4 In PD, ERS forms a complex vicious cycle with mitochondrial dysfunction, oxidative stress, and neuroinflammation, collectively driving disease progression ENSG00000189403 ENSG00000136869 PMC11989508__F1 ER is a membranous network structure in eukaryotic cells, divided into the RER and the SER ENSG00000128272 ENSG00000144895 PMC4042834__F4 An example of a KEGG pathway containing genes involved in multiple processes ENSG00000166869 ENSG00000087095 ENSG00000172680 ENSG00000157764 ENSG00000070831 ENSG00000138798 ENSG00000095015 ENSG00000173039 ENSG00000130159 ENSG00000155903 ENSG00000127191 ENSG00000081189 ENSG00000164305 ENSG00000128272 ENSG00000011566 ENSG00000170458 ENSG00000177606 ENSG00000136997 ENSG00000138032 ENSG00000175104 ENSG00000146648 ENSG00000196712 ENSG00000026103 PMC3847167__F4 Lines/LINS plays a putative dual role in WNT canonical pathway ENSG00000168036 ENSG00000125084 PMC4648177__F3 IG20pa and MADD as antagonists in the TRAIL-induced apoptotic pathway ENSG00000110514 ENSG00000168040 PMC7020748__F2 Key pathways most frequently mutated in MPM all contribute to global downregulation of microRNA levels ENSG00000163930 ENSG00000186575 ENSG00000136997 ENSG00000171791 ENSG00000150457 ENSG00000113360 PMC5500790__F1 Wnt signaling pathways ENSG00000134982 ENSG00000163914 PMC6069411__F1 Canonical Hh signaling pathway ENSG00000128602 PMC17314__F1 An integrated view of the biology of Halobacterium NRC-1 ENSG00000075142 ENSG00000100883 ENSG00000153037 PMC6069411__F2 Canonical Wnt/Beta-catenin signaling pathway [,,,,,,,] ENSG00000137673 ENSG00000134982 ENSG00000172005 ENSG00000026508 PMC11434717__F3 Terpene trilactone biosynthetic pathway ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC7818012__F2 Mass spectrometry-based protein‒protein interaction techniques and their applications in studies of DNA damage repair ENSG00000143799 ENSG00000104884 ENSG00000159259 ENSG00000039650 ENSG00000087206 ENSG00000163918 ENSG00000115350 ENSG00000077514 ENSG00000146143 ENSG00000163322 ENSG00000035928 ENSG00000198056 ENSG00000067369 ENSG00000064933 ENSG00000168101 ENSG00000012048 ENSG00000101868 ENSG00000134899 ENSG00000105486 ENSG00000292191 ENSG00000079246 ENSG00000101773 ENSG00000148229 ENSG00000076924 ENSG00000104320 ENSG00000204086 ENSG00000167670 ENSG00000014138 ENSG00000183624 ENSG00000284832 ENSG00000138346 ENSG00000131747 ENSG00000285246 ENSG00000139618 ENSG00000134574 ENSG00000100387 ENSG00000163945 ENSG00000132646 ENSG00000167986 ENSG00000100479 ENSG00000122008 ENSG00000012061 ENSG00000083093 ENSG00000277273 ENSG00000134480 ENSG00000113318 ENSG00000132383 ENSG00000051180 ENSG00000048028 ENSG00000177084 ENSG00000106628 ENSG00000188486 ENSG00000136492 ENSG00000185515 ENSG00000149311 ENSG00000165392 ENSG00000057468 ENSG00000197299 ENSG00000133119 ENSG00000095002 ENSG00000122512 PMC8962344__F2 Considerations about Hypoxic Changes in Neuraxis Tissue Injuries and Recovery ENSG00000134086 ENSG00000171791 ENSG00000084774 PMC8221351__F9 Mesenchymal stem cells-derived extracellular vesicles ameliorate Alzheimer’s disease in rat models via the microRNA-29c-3p/BACE1 axis and the Wnt/Beta-catenin pathway ENSG00000154342 ENSG00000168036 PMC7527296__F1 IL-6-STAT3 signaling is a potential therapeutic target for COVID-19 mediated by cytokine storm ENSG00000130234 ENSG00000113070 ENSG00000184012 ENSG00000168610 ENSG00000146648 PMC8134730__F7 Osthole Ameliorates Estrogen Deficiency-Induced Cognitive Impairment in Female Mice ENSG00000106683 ENSG00000198793 PMC6539991__F4 Gene-Pathway network ENSG00000002330 ENSG00000010810 ENSG00000132646 ENSG00000171791 ENSG00000112715 ENSG00000117399 PMC6539991__F5 Sub-molecular network of CC, EC and VC ENSG00000171791 ENSG00000145386 ENSG00000112715 PMC6539991__F3 Pathway networks ENSG00000261857 ENSG00000171759 ENSG00000132341 PMC5952219__F2 TLR4 signaling pathway ENSG00000183735 ENSG00000137275 ENSG00000172005 ENSG00000134070 ENSG00000189403 ENSG00000172936 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC2776748__F1 A, Schematic diagram showing intra-cellular functions of the Bcl family of proteins ENSG00000002330 ENSG00000169429 ENSG00000120868 PMC10138871__F7 NpPP2-B10, an F-Box-Nictaba Gene, Promotes Plant Growth and Resistance to Black Shank Disease Incited by Phytophthora nicotianae in Nicotiana tabacum ENSG00000113558 PMC11203709__F3 VHL-mediated signaling/regulatory pathways in ccRCC with respect to PAX involvement ENSG00000134086 ENSG00000134982 ENSG00000198793 ENSG00000136997 ENSG00000168036 ENSG00000075891 ENSG00000092421 PMC4110518__F1 Cellular origin of thyroid carcinomas is shown ENSG00000157764 PMC8536509__F2 MTORC1 by amino acids in mammalian cells: A general picture of recent advances ENSG00000177169 ENSG00000198793 ENSG00000169047 ENSG00000155792 ENSG00000112561 ENSG00000164327 ENSG00000167965 ENSG00000186654 PMC9495330__F13 Modified Montmorillonite Improved Growth Performance of Broilers by Modulating Intestinal Microbiota and Enhancing Intestinal Barriers, Anti-Inflammatory Response, and Antioxidative Capacity ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC7817106__F7 Linkage-specific deubiquitylation by OTUD5 defines an embryonic pathway intolerant to genomic variation ENSG00000196839 ENSG00000196591 ENSG00000100146 PMC4562270__F4 Proteomic approaches for profiling negative fertility markers in inferior boar spermatozoa ENSG00000142192 ENSG00000123416 ENSG00000105329 ENSG00000073578 ENSG00000173039 ENSG00000171791 ENSG00000010256 ENSG00000073756 ENSG00000168610 ENSG00000164305 ENSG00000245848 ENSG00000111537 ENSG00000136997 ENSG00000167468 ENSG00000125538 ENSG00000072110 ENSG00000126895 ENSG00000185591 ENSG00000104388 ENSG00000162692 ENSG00000170571 ENSG00000136732 ENSG00000291368 PMC11666154__F5 LTBP3 combined with SLC (TGFB and LAP via disulfide bonds) significantly strengthen the bioavailability of TGFB ENSG00000114115 PMC7559172__F7 Wnt signaling pathway enriched in KEGG ENSG00000087095 ENSG00000100592 ENSG00000095739 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000148175 ENSG00000168036 ENSG00000196470 ENSG00000185269 PMC2131730__F4 LPS signals the TLR4 pathway on an APC (i.e., monocyte or dendritic cell) ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC3278537__F2 Signaling Pathways Underlying the Pathophysiology and Treatment of Depression: Novel Mechanisms for Rapid-Acting Agents PMC9678415__F7 Systematic review of the biological mediators of fat taste and smell ENSG00000185933 ENSG00000167323 ENSG00000291971 ENSG00000070985 PMC6598280__F2 Paracrine effects of the ASC secretome and involved pathways ENSG00000170962 ENSG00000132693 PMC9030409__F4 Personalized Diagnosis in Differentiated Thyroid Cancers by Molecular and Functional Imaging Biomarkers: Present and Future ENSG00000105641 ENSG00000141867 ENSG00000157764 ENSG00000198793 ENSG00000086991 ENSG00000134853 PMC3654375__F2A Guidance from above: common cues direct distinct signaling outcomes in vascular and neural patterning ENSG00000010810 PMC12041035__F3 Exosomes mediate crosstalk between kidney cells ENSG00000135605 ENSG00000159399 PMC8798716__F9 Identifying the potential regulators of neutrophils recruitment in hepatocellular carcinoma using bioinformatics method ENSG00000213658 ENSG00000196839 ENSG00000163914 ENSG00000171540 ENSG00000084774 PMC12041035__F5 Exosomes mediate cell regeneration, repair, and fibrosis ENSG00000159399 PMC7196612__F2 Virulence factors of Fusobacterium (F.) nucleatum ENSG00000177169 ENSG00000181847 ENSG00000172936 PMC7196612__F3 Oncogenic properties of Bacteroides (B.) fragilis ENSG00000168036 ENSG00000168610 PMC4269881__F6 EHEC-host interactome reveals novel targets for the translocated intimin receptor ENSG00000116983 ENSG00000125826 ENSG00000175866 ENSG00000144401 ENSG00000070831 ENSG00000102871 ENSG00000269335 ENSG00000127191 ENSG00000091073 ENSG00000150991 ENSG00000170458 ENSG00000291814 ENSG00000082512 ENSG00000136869 ENSG00000172936 ENSG00000127824 ENSG00000175104 ENSG00000184216 PMC7232345__F7 Proposed model for OAS2 regulation of ZIKV replication and IFN pathway ENSG00000213928 ENSG00000115415 ENSG00000276561 PMC12041035__F1 Biogenesis, secretion, and structure of exosomes ENSG00000085117 ENSG00000110651 ENSG00000010278 ENSG00000135404 PMC4123081__F1 Simplified schematic representation of the extrinsic and the intrinsic (mitochondrial) pathways of apoptosis and necroptosis ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC4133905__F2 Normal, physiological insulin signaling transduction (left) and an altered pathway following insulin withdrawal (right) in adult hippocampal neural stem cells ENSG00000198793 PMC4123081__F4 Ingenuity Pathway Analysis of the miRNAs identified as involved in regulation of cardiomyocyte apoptosis (see ) ENSG00000109452 ENSG00000170965 ENSG00000130158 ENSG00000163209 ENSG00000137648 ENSG00000027644 ENSG00000137872 ENSG00000281518 ENSG00000140274 ENSG00000161055 ENSG00000167900 ENSG00000100228 ENSG00000079557 ENSG00000165449 ENSG00000169618 ENSG00000187688 ENSG00000111729 ENSG00000111537 ENSG00000116194 ENSG00000054965 ENSG00000096717 PMC11211753__F6 Possible mechanisms of action of TR for altering ECM turnover ENSG00000122194 PMC8430761__F1 Multiple Leptin Signalling Pathways in the Control of Metabolism and Fertility: A Means to Different Ends? ENSG00000171105 ENSG00000178188 ENSG00000164326 ENSG00000198793 ENSG00000115138 ENSG00000133124 ENSG00000170498 ENSG00000168610 ENSG00000105662 PMC6925433__F4 The insulin signal pathway ENSG00000171105 ENSG00000002330 ENSG00000110395 ENSG00000198793 ENSG00000026103 PMC8062261__F12 TNF receptor-associated factor 6 (TRAF6) plays crucial roles in multiple biological systems through polyubiquitination-mediated NFKB activation ENSG00000121058 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC3271076__F8 Novel YY1-miR-1 Regulatory Circuit in Skeletal Myogenesis Revealed by Genome-Wide Prediction of YY1-miRNA Network ENSG00000100811 ENSG00000101868 ENSG00000009709 ENSG00000070831 ENSG00000164107 ENSG00000118971 PMC3654375__F1A Guidance from above: common cues direct distinct signaling outcomes in vascular and neural patterning ENSG00000172602 ENSG00000187764 ENSG00000126458 PMC7605384__F6 Network of the tRF-mRNA-pathway constructed with 7 selected tRFs (5 were upregulated and, 2 were downregulated) and their target gene ENSG00000163637 ENSG00000102962 ENSG00000168329 ENSG00000178585 ENSG00000160551 ENSG00000134215 ENSG00000173218 ENSG00000115904 ENSG00000149782 ENSG00000089159 ENSG00000149269 ENSG00000006116 ENSG00000077782 ENSG00000136068 ENSG00000158050 ENSG00000142408 ENSG00000005339 ENSG00000101109 ENSG00000108861 ENSG00000078369 ENSG00000173039 ENSG00000165059 ENSG00000182621 ENSG00000284953 ENSG00000168610 ENSG00000081189 ENSG00000186810 ENSG00000164742 ENSG00000148660 ENSG00000100592 ENSG00000067606 ENSG00000112640 ENSG00000115266 ENSG00000109270 ENSG00000104290 ENSG00000102312 ENSG00000146122 ENSG00000067191 ENSG00000076716 ENSG00000161202 ENSG00000127588 ENSG00000285485 ENSG00000105605 ENSG00000069966 ENSG00000143184 ENSG00000164086 PMC4142057__F1 Activation of NFKB signaling through canonical and alternative pathways ENSG00000104856 PMC4142057__F2 NFKB and p53 antagonises each others activity ENSG00000175054 PMC6350063__F1 Understanding the Role of Antiviral Cytokines and Chemokines on Neural Stem/Progenitor Cell Activity and Survival ENSG00000128342 ENSG00000114315 ENSG00000168610 ENSG00000164305 PMC10605306__F1 Interleukin-33 signaling pathway ENSG00000137033 ENSG00000172936 ENSG00000175104 PMC4059820__F2 Signaling through T1R2/T1R3 in type II cells of taste buds, in the gut and in the B cells of the pancreas ENSG00000070985 ENSG00000137841 PMC2632675__F3 Cell cycle pathways in S ENSG00000257949 ENSG00000124610 ENSG00000197971 PMC4517052__F1 Main metabolic pathway in the bioactivation and DNA adduct formation of BaP in lung ENSG00000005381 ENSG00000140465 PMC4074570__F3 Regulation of receptor-mediated endocytosis by CRL pathways ENSG00000184995 ENSG00000100387 ENSG00000113558 ENSG00000142166 PMC3900881__F3 Sugar for the brain: the role of glucose in physiological and pathological brain function ENSG00000078237 PMC5840209__F3 Apoptosis signaling pathways ENSG00000100290 ENSG00000002330 PMC5418249__F1 PD-1:PD-L1 mechanisms between T-cells and tumor cells ENSG00000291603 ENSG00000134982 ENSG00000198793 PMC11904106__F1 Targeting intracellular autophagic process for the treatment of post‐stroke ischemia/reperfusion injury ENSG00000138798 PMC3904431__F3 Targeting MicroRNAs in Cancer: Rationale, Strategies and Challenges ENSG00000087245 ENSG00000157404 ENSG00000128710 ENSG00000070831 ENSG00000172216 ENSG00000105991 ENSG00000124766 ENSG00000185591 ENSG00000105810 ENSG00000171791 PMC6137199__F6 Predicted target genes of miR-125a-5p and let-7e-5p in the Inflammatory response molecular network ENSG00000243414 ENSG00000151490 ENSG00000170909 ENSG00000157404 ENSG00000111981 ENSG00000122420 ENSG00000163599 ENSG00000171049 ENSG00000103222 ENSG00000112715 ENSG00000121807 ENSG00000118777 ENSG00000109787 ENSG00000136826 ENSG00000182511 ENSG00000145623 ENSG00000056558 ENSG00000180008 ENSG00000090376 ENSG00000140678 ENSG00000169896 ENSG00000099985 ENSG00000196562 ENSG00000145777 ENSG00000110324 ENSG00000105639 ENSG00000073756 ENSG00000132693 ENSG00000132170 ENSG00000057593 ENSG00000188130 ENSG00000083799 PMC7377858__F6 circRNA-miRNA-mRNA network ENSG00000197579 ENSG00000134533 ENSG00000134982 ENSG00000144228 ENSG00000182263 PMC3544775__F3 Laminin-211 in skeletal muscle function ENSG00000002330 PMC5543893__F8 Involvement of KRT23 in the cell cycle: G1/S check point pathway ENSG00000172216 ENSG00000276644 ENSG00000124762 PMC7835019__F9 Proposed model depicting the involvement of the eNOS/cGMP/PKG pathway in PF activation ENSG00000157404 ENSG00000198793 ENSG00000109670 PMC9071930__F7 Palovarotene Can Attenuate Heterotopic Ossification Induced by Tendon Stem Cells by Downregulating the Synergistic Effects of Smad and NFKB Signaling Pathway following Stimulation of the Inflammatory Microenvironment ENSG00000125398 ENSG00000100985 ENSG00000125968 PMC3411066__F6 Formation and function of 16:1-PI in the signaling of the lipokine 16:1 in Swiss 3T3 cells ENSG00000173599 ENSG00000158669 ENSG00000198670 ENSG00000186281 ENSG00000026103 PMC5481559__F14 Proposed model for persistent fibrosis in mice after lung injury ENSG00000170961 ENSG00000186792 ENSG00000086991 PMC9004589__F6 Astrocytes: The Housekeepers and Guardians of the CNS ENSG00000133107 ENSG00000104321 ENSG00000144935 ENSG00000072315 PMC8363454__F6 Colonic Epithelial PHLPP2 Deficiency Promotes Colonic Epithelial Pyroptosis by Activating the NFKB Signaling Pathway ENSG00000040199 ENSG00000150455 PMC9095844__F1 Thioredoxin-1: A Promising Target for the Treatment of Allergic Diseases ENSG00000183625 ENSG00000010671 PMC4526652__F7 Functional Local Renin-Angiotensin System in Human and Rat Periodontal Tissue PMC9563430__F9 PRELP Regulates Cell–Cell Adhesion and EMT and Inhibits Retinoblastoma Progression ENSG00000002330 ENSG00000105327 ENSG00000070831 ENSG00000153094 ENSG00000134982 ENSG00000291971 ENSG00000168036 ENSG00000087586 ENSG00000135341 ENSG00000164305 ENSG00000170365 ENSG00000168214 ENSG00000144554 ENSG00000104320 ENSG00000136997 ENSG00000139687 ENSG00000253729 ENSG00000005339 ENSG00000168040 ENSG00000149311 ENSG00000017797 ENSG00000110395 ENSG00000177606 ENSG00000109270 ENSG00000080839 PMC9563430__F5 PRELP Regulates Cell–Cell Adhesion and EMT and Inhibits Retinoblastoma Progression ENSG00000149311 ENSG00000087095 ENSG00000107404 ENSG00000105327 ENSG00000002330 ENSG00000291971 ENSG00000087586 ENSG00000171791 ENSG00000168040 ENSG00000135341 ENSG00000139687 ENSG00000253729 PMC9247880__F2 Molecular Genetics and Targeted Therapies for Paediatric High-grade Glioma ENSG00000157764 ENSG00000135446 ENSG00000198793 ENSG00000136997 ENSG00000134853 ENSG00000123374 ENSG00000105810 ENSG00000146648 ENSG00000196712 ENSG00000198625 PMC3824005__F3 Canonical and noncanonical functions of the apoptotic machinery ENSG00000157064 PMC3314482__F1 Chk’ing p53-deficient breast cancers ENSG00000149311 ENSG00000175054 ENSG00000183691 ENSG00000123374 PMC3824005__F1 Core components of the apoptotic machinery PMC4095906__F3 TLR and BCR signaling and integration in CSR and antibody responses ENSG00000104856 ENSG00000239732 ENSG00000186716 ENSG00000198793 ENSG00000172005 ENSG00000197943 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC3656649__F1 ENDOCRINE RESISTANCE IN BREAST CANCER ENSG00000291971 ENSG00000185591 ENSG00000146648 PMC8493254__F5 Proteome Modulation in Peripheral Blood Mononuclear Cells of Peste des Petits Ruminants Vaccinated Goats and Sheep ENSG00000124256 ENSG00000187608 ENSG00000157601 ENSG00000185745 ENSG00000136869 ENSG00000291555 ENSG00000121060 ENSG00000164342 ENSG00000076604 ENSG00000064195 PMC8493254__F6 Proteome Modulation in Peripheral Blood Mononuclear Cells of Peste des Petits Ruminants Vaccinated Goats and Sheep ENSG00000274211 ENSG00000124256 ENSG00000213928 ENSG00000187608 ENSG00000105939 ENSG00000167604 ENSG00000185745 ENSG00000148935 ENSG00000276561 ENSG00000142166 ENSG00000134321 ENSG00000115415 ENSG00000168310 ENSG00000180008 ENSG00000121060 PMC12192923__F2 The cGAS-STING pathway in health and cancer therapy ENSG00000183735 ENSG00000164430 PMC7998005__F8 miR-135a-5p mediates memory and synaptic impairments via the Rock2/Adducin1 signaling pathway in a mouse model of Alzheimer’s disease ENSG00000187140 ENSG00000087274 PMC7554708__F3 Representative pathways involved in the metabolism of diacylglycerol (DAG) and phosphatidic acid (PA) ENSG00000173599 ENSG00000198670 PMC7282166__F1 Protein-protein network of the 186 exposure genes ENSG00000105835 ENSG00000099985 ENSG00000148926 ENSG00000124107 ENSG00000120885 ENSG00000143858 ENSG00000136732 ENSG00000158050 ENSG00000132341 PMC9304296__F2 DNA damage response proteins in canine cancer as potential research targets in comparative oncology ENSG00000012048 ENSG00000175054 ENSG00000083093 ENSG00000051180 ENSG00000139618 PMC6819196__F8 HIPPO SIGNALING CONTROLS NLRP3 ACTIVATION AND GOVERNS IMMUNOREGULATION OF MESENCHYMAL STEM CELLS IN MOUSE LIVER INJURY ENSG00000178860 ENSG00000162711 ENSG00000168036 ENSG00000100219 ENSG00000150457 ENSG00000131023 PMC9304296__F4 DNA damage response proteins in canine cancer as potential research targets in comparative oncology ENSG00000175054 ENSG00000164053 PMC5460284__F4 Network model describing association of hyperactivated mTOR signaling with developmental and morphological defects in forebrains ENSG00000167508 PMC11663879__F4 Molecular mechanism and RNA modification with their functions in Macrophage ENSG00000115415 ENSG00000198492 ENSG00000146457 PMC6121658__F1 MDSCs expansion is regulated by several factors in vivo microenvironment ENSG00000137033 ENSG00000198793 ENSG00000168610 ENSG00000106546 PMC6997465__F1 Immune system and nociceptor activation ENSG00000104321 ENSG00000198793 ENSG00000134369 ENSG00000196689 PMC3757395__F1 Scheme of miRNA processing pathway ENSG00000113360 PMC8389290__F7 Uncovering Mechanisms of Zanthoxylum piperitum Fruits for the Alleviation of Rheumatoid Arthritis Based on Network Pharmacology ENSG00000150991 ENSG00000138798 ENSG00000183979 ENSG00000111837 ENSG00000100979 ENSG00000165269 PMC9362873__F1 LILRB4, an immune checkpoint on myeloid cells ENSG00000186716 ENSG00000118520 ENSG00000186818 ENSG00000274513 PMC10385954__F13 Putative mechanism of artemisinin neuroprotective action against 6-OHDA and MPP+-induced neuronal injury ENSG00000291971 ENSG00000010810 PMC4835965__F4 ER stress and autophagy in AD ENSG00000162711 ENSG00000178607 ENSG00000125538 ENSG00000120885 ENSG00000258102 PMC5406529__F1 T cell immune checkpoints for anti‐tumor immunity ENSG00000291603 ENSG00000163599 PMC8636279__F2 Helminth extracellular vesicles: Interactions with the host immune system ENSG00000137033 ENSG00000198793 PMC5965688__F8 Nm23-H1 in cell cycle regulation and apoptosis ENSG00000135446 ENSG00000105810 PMC7253339__F1 NPC and associated factors ENSG00000132341 PMC3386226__F8 Rad4TopBP1 ATR-Activation Domain Functions in G1/S Phase in a Chromatin-Dependent Manner ENSG00000175054 ENSG00000164053 ENSG00000148204 PMC4030989__F1 Sphingolipid pathway and basic structural units of sphingolipid biosynthesis ENSG00000139624 ENSG00000100422 ENSG00000063176 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000143753 ENSG00000285281 ENSG00000168350 ENSG00000143418 ENSG00000163082 PMC9315226__F4 ERK5 Signalling and Resistance to ERK1/2 Pathway Therapeutics: The Path Less Travelled? ENSG00000141867 ENSG00000157764 PMC4190013__F1 Signal transduction pathway for type I IFNs and a summary of key ISG effects on the virus and mucosal immune response during influenza ENSG00000169245 ENSG00000213928 ENSG00000105397 ENSG00000135828 ENSG00000276561 PMC5511157__F6 Mediation by Menin of milk protein synthesis through the PI3K/Akt/mTOR signaling pathway in mammary epithelial cells ENSG00000198793 ENSG00000113494 PMC3514012__F5 IPA generates IL-17C interactome ENSG00000110944 ENSG00000148346 ENSG00000081041 ENSG00000100906 ENSG00000109320 ENSG00000056972 ENSG00000125347 ENSG00000124391 ENSG00000136688 ENSG00000108691 ENSG00000111537 ENSG00000077150 ENSG00000134070 ENSG00000164400 PMC3888473__F3 Top genes from SNP comparative analysis ENSG00000019991 ENSG00000167910 ENSG00000197408 ENSG00000130649 ENSG00000103222 ENSG00000255974 ENSG00000171791 ENSG00000112715 ENSG00000118777 ENSG00000158125 ENSG00000275331 ENSG00000114770 ENSG00000187048 ENSG00000136997 ENSG00000150907 ENSG00000125538 ENSG00000160179 ENSG00000116044 ENSG00000140465 ENSG00000073756 ENSG00000134716 ENSG00000007171 ENSG00000132646 ENSG00000100985 ENSG00000162692 ENSG00000023839 PMC3888473__F4 Pathway analysis on SNPs that affect gene expression and drug response ENSG00000122566 ENSG00000185052 ENSG00000134419 ENSG00000122863 ENSG00000173930 ENSG00000087085 ENSG00000185591 ENSG00000092199 ENSG00000186204 PMC8481945__F2 Melanoma Plasticity: Promoter of Metastasis and Resistance to Therapy ENSG00000167601 ENSG00000147862 ENSG00000157764 ENSG00000169071 ENSG00000148400 ENSG00000136997 ENSG00000135903 ENSG00000168036 ENSG00000146648 ENSG00000064300 PMC4574966__F3 Multi-Marker Genetic Association Test Based on the Rasch Model Applied to Alzheimer’s Disease ENSG00000070756 ENSG00000242689 ENSG00000078900 ENSG00000170027 ENSG00000100412 ENSG00000176046 ENSG00000166851 ENSG00000066427 ENSG00000181026 PMC5347792__F9 Galectin-1 induces invasion and the epithelial-mesenchymal transition in human gastric cancer cells via non-canonical activation of the hedgehog signaling pathway ENSG00000164690 ENSG00000128602 PMC4348060__F5 Differential network of breast cancer Cell Cycle pathway between early recurrent and non-recurrent patients ENSG00000149311 ENSG00000005339 ENSG00000156970 ENSG00000175793 ENSG00000081377 ENSG00000130222 ENSG00000101224 ENSG00000076003 ENSG00000139687 PMC3716752__F1 Toward understanding the genetics of regulatory T cells in ovarian cancer ENSG00000090104 ENSG00000134982 ENSG00000163599 ENSG00000049768 PMC9534897__F4 Extracranial arteriovenous malformations demonstrate dysregulated TGFB/BMP signaling and increased circulating TGFB1 ENSG00000170365 ENSG00000137834 ENSG00000135547 ENSG00000114315 PMC6304875__F1 General overview of the autophagic pathway and its regulators ENSG00000177169 ENSG00000083290 ENSG00000198793 PMC7600068__F2 Potential mechanism of radiation-induced abscopal effect ENSG00000149311 ENSG00000146648 PMC4619526__F1 Genetic Polymorphisms in Vitamin D Metabolism and Signaling Genes and Risk of Breast Cancer: A Nested Case-Control Study ENSG00000111012 ENSG00000172893 ENSG00000019186 ENSG00000186104 PMC9315226__F2 ERK5 Signalling and Resistance to ERK1/2 Pathway Therapeutics: The Path Less Travelled? ENSG00000169967 ENSG00000157764 ENSG00000213999 ENSG00000291761 ENSG00000166484 ENSG00000081189 ENSG00000137764 PMC6769649__F3 Ligand-dependent EGFR signaling pathways ENSG00000110395 ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC9315226__F3 ERK5 Signalling and Resistance to ERK1/2 Pathway Therapeutics: The Path Less Travelled? ENSG00000157764 ENSG00000291971 ENSG00000146648 ENSG00000140443 PMC7950238__F5 Signaling pathway diagram ENSG00000278718 ENSG00000162711 ENSG00000285109 ENSG00000265972 PMC9315226__F1 ERK5 Signalling and Resistance to ERK1/2 Pathway Therapeutics: The Path Less Travelled? ENSG00000157764 PMC4309433__F1 Metabolic network of tomato cells ENSG00000122966 ENSG00000172005 ENSG00000133028 ENSG00000167900 ENSG00000062485 ENSG00000026103 PMC7642048__F1 Mechanical stretch-induced signaling pathway in VSMCs ENSG00000291971 ENSG00000163568 ENSG00000061273 ENSG00000096717 ENSG00000140443 PMC8846306__F2 Running ‘LAPS’ Around nLD: Nuclear Lipid Droplet Form and Function ENSG00000158669 ENSG00000198670 ENSG00000062282 PMC7988785__F1 An update on brown adipose tissue biology: a discussion of recent findings ENSG00000145824 ENSG00000105550 ENSG00000102678 ENSG00000163702 PMC10380532__F2 mTOR Signaling Pathway and Gut Microbiota in Various Disorders: Mechanisms and Potential Drugs in Pharmacotherapy ENSG00000101407 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC3912166__F1 Establishment of HeLa Cell Mutants Deficient in Sphingolipid-Related Genes Using TALENs ENSG00000158470 ENSG00000115525 ENSG00000148154 PMC10380532__F3 mTOR Signaling Pathway and Gut Microbiota in Various Disorders: Mechanisms and Potential Drugs in Pharmacotherapy ENSG00000137033 ENSG00000198793 ENSG00000168610 PMC540032__F1 CellDesigner () diagram of the insulin/IGF receptor signaling pathway ENSG00000171105 ENSG00000005882 ENSG00000169047 ENSG00000198793 ENSG00000133124 PMC3868461__F7 Essential regulation of cell bioenergetics in Trypanosoma brucei by the mitochondrial calcium uniporter ENSG00000122966 ENSG00000172005 ENSG00000026103 PMC7191095__F3 Main signal pathways of YTHDF2 in human cancers ENSG00000120833 ENSG00000170558 ENSG00000198492 ENSG00000125538 ENSG00000065559 ENSG00000146648 ENSG00000165819 PMC2045534__F6 Schematic model of the role played by GADD34 and the mTOR pathway in the suppression of viral replication ENSG00000198793 PMC10741975__F5 Compound-pathway network has 41 points and 151 lines ENSG00000186810 ENSG00000050748 ENSG00000135446 ENSG00000183625 ENSG00000198793 ENSG00000197442 ENSG00000006062 ENSG00000121879 ENSG00000171608 ENSG00000121807 ENSG00000105639 ENSG00000143387 PMC7267062__F2 Death receptor apoptotic pathway in cancer induced by plant polysaccharides ENSG00000168040 ENSG00000026103 PMC10741975__F7 Chemokine signaling pathway and PI3K-Akt signaling pathway influenced by esaxerenone ENSG00000291971 ENSG00000138798 ENSG00000183625 ENSG00000123374 ENSG00000171608 ENSG00000121807 ENSG00000105639 ENSG00000146648 ENSG00000124762 PMC7267062__F1 Mitochondrial apoptotic pathway in cancer induced by plant polysaccharides ENSG00000002330 ENSG00000026103 PMC7555774__F3 Inhibitory signaling events against AngII/AT1R-mediated senescence in VSMC ENSG00000096717 ENSG00000142082 ENSG00000057663 PMC8802973__F1 Safety and danger of biologic treatments in psoriasis in context of cutaneous T-cell lymphoma (CTCL) ENSG00000105639 ENSG00000168610 PMC3384423__F1 MTOR signaling pathway ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000196712 ENSG00000132341 PMC8669293__F6 Profound changes in cerebrospinal fluid proteome and metabolic profile are associated with congenital hydrocephalus ENSG00000163848 ENSG00000185591 ENSG00000036473 PMC8669293__F4 Profound changes in cerebrospinal fluid proteome and metabolic profile are associated with congenital hydrocephalus ENSG00000037280 PMC6600524__F1 Schematic representation of androgen deprivation therapy (ADT) or androgen receptor (AR) antagonist in mediating therapeutic resistance and neuroendocrine (NE) differentiation of prostate cancer (PCa) ENSG00000108691 ENSG00000095303 ENSG00000128342 ENSG00000124664 PMC8194090__F7 Molecular Mechanisms of Chondrocyte Proliferation and Differentiation ENSG00000125398 PMC6944213__F6 Genotype, phenotype, and dose effects on Bcl6 inhibition upstream of the secreted factors canonical pathway ENSG00000111537 ENSG00000168811 PMC8194090__F5 Molecular Mechanisms of Chondrocyte Proliferation and Differentiation ENSG00000125398 PMC8194090__F3 Molecular Mechanisms of Chondrocyte Proliferation and Differentiation ENSG00000125398 ENSG00000128602 ENSG00000163501 PMC2949081__F1 Summary of the RAS incorporating the Ang peptide family and physiological effects mediated via ATR subtypes ENSG00000175054 ENSG00000130234 PMC3770247__F1 Hedgehog signaling pathway, a morphogenic signaling pathway important in embryogenesis, tissue differentiation, cell growth and development ENSG00000164690 ENSG00000128602 PMC8194090__F2 Molecular Mechanisms of Chondrocyte Proliferation and Differentiation ENSG00000281324 ENSG00000125398 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC7555140__F1 Small heat shock proteins (sHSPs) regulate apoptosis in the extrinsic and intrinsic apoptotic pathways ENSG00000168040 ENSG00000164305 PMC7249327__F3 From progesterone to Cdk1 activation: the scattered elements of a not fully understood signalling pathway ENSG00000112367 ENSG00000172680 ENSG00000128989 ENSG00000276876 PMC7552005__F1 PKR at the crossroads of virus sensing, innate immune signaling, and stress response pathways ENSG00000183735 ENSG00000088888 ENSG00000128272 ENSG00000144895 ENSG00000082512 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC5467017__F8 Working model portraying the effects of WNT/Beta-catenin signaling in PTENWT melanoma cells under nutrient starvation conditions ENSG00000134982 ENSG00000168036 PMC11851658__F1 Pexophagy-related peroxisomal proteins ENSG00000142655 ENSG00000198793 ENSG00000288217 ENSG00000113790 ENSG00000162928 ENSG00000034693 ENSG00000121680 PMC4017408__F1 Wnt signaling pathway ENSG00000134982 ENSG00000168036 PMC6902583__F6 Target network of bradycardia ENSG00000180720 ENSG00000132109 ENSG00000175206 ENSG00000150594 ENSG00000152661 ENSG00000111262 ENSG00000138622 ENSG00000253506 ENSG00000170214 ENSG00000006283 ENSG00000103569 ENSG00000086991 ENSG00000143839 ENSG00000117152 ENSG00000091879 ENSG00000115718 ENSG00000043591 ENSG00000274286 ENSG00000112038 ENSG00000133019 ENSG00000075213 ENSG00000119125 PMC11851658__F2 ROS function as signaling mediators in pexophagy ENSG00000149311 ENSG00000112561 ENSG00000288217 ENSG00000164751 PMC5541090__F1 NREP, HIPK2, PRDM16, SMAD3 and their roles in the canonical TGFB signalling pathway ENSG00000142611 ENSG00000134986 ENSG00000064393 PMC7462746__F6 cGAS-STING Pathway inhibition by HCQ and CQ: DNA sensor cGAS (cyclic GMP-AMP synthase) can recognize DNA of viral/bacterial origin and synthesize a dinucleotide molecule, cGAMP (2′, 5′-cyclic GMP-AMP dinucleotide) ENSG00000164430 PMC2647628__F1 CATERPILLER (NLR) Family Members as Positive and Negative Regulators of Inflammatory Responses ENSG00000104856 ENSG00000107562 ENSG00000173039 ENSG00000172936 ENSG00000184216 ENSG00000121966 PMC7906184__F10 Graphic depiction of the conclusion from the present study ENSG00000185591 PMC7779278__F3 Pyruvate dehydrogenase kinase (PDK) in immune cell metabolism ENSG00000135218 PMC3348846__F2 Leukocyte recruitment to sites of injury/infection: dominant role of ROS ENSG00000189403 ENSG00000136869 ENSG00000162692 PMC4588544__F3 Current models for mitochondrial longevity ENSG00000144895 ENSG00000198793 ENSG00000130699 PMC3348846__F3 Role of Rac1/RhoA balance in endothelial barrier integrity: impact of ROS and NO ENSG00000070831 ENSG00000163914 PMC8546260__F1 TNFA/TNFR2 Pathway: Targeting a Brake to Release the Anti-tumor Immune Response ENSG00000137275 ENSG00000102871 ENSG00000166278 ENSG00000168040 ENSG00000127191 ENSG00000285379 PMC9294282__F3 Chromatin Ubiquitination Guides DNA Double Strand Break Signaling and Repair ENSG00000083093 ENSG00000063978 ENSG00000134982 ENSG00000080345 ENSG00000168411 ENSG00000139618 ENSG00000112130 ENSG00000276043 ENSG00000079999 ENSG00000012048 ENSG00000163961 ENSG00000102226 ENSG00000051180 ENSG00000109670 PMC3050844__F5 Aberrant Cell Cycle and Apoptotic Changes Characterise Severe Influenza A Infection – A Meta-Analysis of Genomic Signatures in Circulating Leukocytes ENSG00000172005 ENSG00000250506 ENSG00000102974 PMC5337806__F5 TGFB signaling pathway ENSG00000170365 ENSG00000137834 ENSG00000111537 ENSG00000095739 ENSG00000100387 ENSG00000198742 ENSG00000113558 ENSG00000185591 ENSG00000205250 PMC7779278__F1 Pivotal role of pyruvate dehydrogenase kinase 4 (PDK4) in regulating the metabolic switch between glucose and fatty acid oxidation in skeletal muscle in physiological and pathological conditions ENSG00000135218 ENSG00000150907 ENSG00000169047 PMC5337806__F3 MAPK signaling pathway ENSG00000087095 ENSG00000172680 ENSG00000070831 ENSG00000170458 ENSG00000138798 ENSG00000177606 ENSG00000130159 ENSG00000101224 ENSG00000175104 ENSG00000146648 ENSG00000081189 PMC8067602__F4 Necroptopic signaling pathway ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 PMC5629629__F8 Proposed model of the cell autophagy induced by SAHA and TRAIL DR5-CTSB in breast cancer cell lines ENSG00000198793 PMC9684732__F4 Endoplasmic reticulum of trypanosomatids: An unrevealed road for chemotherapy ENSG00000128272 ENSG00000042832 ENSG00000100219 ENSG00000127191 ENSG00000076604 PMC2938097__F6 TNF/Fas/TRAIL signaling pathway ENSG00000161955 ENSG00000061273 ENSG00000158796 ENSG00000127191 ENSG00000113194 ENSG00000185104 ENSG00000026103 PMC9544065__F12 Revisiting the therapeutic potential of tocotrienol ENSG00000144895 ENSG00000131323 ENSG00000171791 PMC4369380__F1 Distinct Integrin-Dependent Signals Define Requirements for Lytic Granule Convergence and Polarization in Natural Killer Cells ENSG00000291971 PMC5406714__F1 Targeted Inhibition of Hepatocyte Growth Factor (HGF)/c-Met Signaling in Head and Neck Squamous Cell Carcinoma (HNSCC) ENSG00000019991 ENSG00000168610 PMC6895828__F4 The cancer signaling pathway and protein network analysis of these up-regulated targets and the prognostic model of the ten-hub gene signature ENSG00000105327 ENSG00000125735 ENSG00000163083 ENSG00000141068 ENSG00000121807 ENSG00000100385 ENSG00000128917 ENSG00000074181 ENSG00000089685 ENSG00000138755 ENSG00000173578 ENSG00000113749 ENSG00000001626 ENSG00000162892 ENSG00000101333 ENSG00000023445 ENSG00000151882 ENSG00000152689 ENSG00000043462 ENSG00000091879 ENSG00000170962 ENSG00000169220 ENSG00000118503 ENSG00000163235 ENSG00000102245 ENSG00000143507 ENSG00000067191 ENSG00000151617 ENSG00000146648 ENSG00000169248 ENSG00000291603 ENSG00000105329 ENSG00000102871 ENSG00000095015 ENSG00000158517 ENSG00000103522 ENSG00000112715 ENSG00000174564 ENSG00000064300 ENSG00000184381 ENSG00000145623 ENSG00000129946 ENSG00000128052 ENSG00000160179 ENSG00000104432 ENSG00000198286 ENSG00000026103 ENSG00000171105 ENSG00000089041 ENSG00000169860 ENSG00000054967 ENSG00000105639 ENSG00000180767 ENSG00000273936 ENSG00000171310 ENSG00000117322 ENSG00000215788 ENSG00000160691 ENSG00000115607 ENSG00000243789 ENSG00000096996 ENSG00000157368 ENSG00000171777 ENSG00000105122 ENSG00000127533 ENSG00000184371 ENSG00000153395 ENSG00000243646 ENSG00000126353 ENSG00000049249 ENSG00000028137 ENSG00000159399 PMC4040907__F6 The impact of 5q deletion upon myeloid cell fate ENSG00000245848 ENSG00000140968 ENSG00000122877 ENSG00000177733 ENSG00000166886 ENSG00000179348 PMC4774567__F1 Target function of MALAT-1 in cancer ENSG00000164736 ENSG00000185591 ENSG00000105810 PMC7569310__SF1 Transient Receptor Potential Ankyrin-1 and Vanilloid-3 Differentially Regulate Endoplasmic Reticulum Stress and Cytotoxicity in Human Lung Epithelial Cells After Pneumotoxic Wood Smoke Particle Exposure ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000162772 PMC7565963__F1 Hedgehog signaling pathway ENSG00000144857 ENSG00000166813 ENSG00000128602 PMC11967251__F7 Mechanism graphic in this study ENSG00000291971 ENSG00000168610 ENSG00000136231 ENSG00000150630 PMC3990910__F3 Mechanisms of Notch signaling silencing in AML ENSG00000283780 ENSG00000196782 ENSG00000273529 ENSG00000106003 PMC3990910__F1 Mammal Notch receptors, ligands, and canonical activation pathway ENSG00000148400 ENSG00000198435 ENSG00000074181 ENSG00000138798 ENSG00000137845 PMC6539122__F7 Interaction network of proteins involved in cancer, immune system, and signal transduction pathways ENSG00000140992 ENSG00000070190 ENSG00000100519 ENSG00000241553 ENSG00000108654 ENSG00000141068 ENSG00000088256 ENSG00000155903 ENSG00000113558 ENSG00000136997 ENSG00000105810 ENSG00000160293 ENSG00000064012 ENSG00000182578 ENSG00000167088 ENSG00000170027 ENSG00000078369 ENSG00000198561 ENSG00000100345 ENSG00000213341 ENSG00000120063 ENSG00000175166 ENSG00000167986 ENSG00000173692 ENSG00000175792 ENSG00000047410 ENSG00000291603 ENSG00000070831 ENSG00000110651 ENSG00000197442 ENSG00000121966 ENSG00000010671 ENSG00000169967 ENSG00000150782 ENSG00000163840 ENSG00000126803 ENSG00000166501 ENSG00000026652 ENSG00000120868 ENSG00000124181 ENSG00000169375 ENSG00000081237 ENSG00000196839 ENSG00000078668 ENSG00000281877 ENSG00000127191 ENSG00000168610 ENSG00000281614 ENSG00000177189 ENSG00000148660 ENSG00000185627 ENSG00000173757 ENSG00000138756 ENSG00000177606 ENSG00000280477 ENSG00000006747 ENSG00000100784 ENSG00000063601 ENSG00000126353 ENSG00000150867 ENSG00000161202 ENSG00000115825 ENSG00000099804 ENSG00000100365 ENSG00000145349 ENSG00000047315 ENSG00000111642 ENSG00000138385 PMC7514027__F6 Vanadium-protein complex inhibits human adipocyte differentiation through the activation of Beta-catenin and LKB1/AMPK signaling pathway ENSG00000168036 ENSG00000026103 PMC3393821__F2 Altered expression of cytokine signaling pathway genes in peripheral blood cells of alcohol dependent subjects: Preliminary findings ENSG00000104856 ENSG00000077150 ENSG00000137275 ENSG00000164136 ENSG00000103522 ENSG00000171791 ENSG00000105639 ENSG00000127191 ENSG00000168610 ENSG00000142166 PMC3384423__F4 CRLs/SCF E3 ubiquitin ligases regulate mTOR pathway ENSG00000134086 ENSG00000044090 ENSG00000081913 ENSG00000100387 ENSG00000198793 ENSG00000139842 PMC4456188__F1 Mechanisms by which Beta-cell failure an apoptosis occur are complex, not completely unraveled and involve the interplay of numerous factors and conditions ENSG00000178573 ENSG00000169047 ENSG00000198793 ENSG00000139515 ENSG00000162772 PMC12004233__F5 Significant differentially expressed unigenes enriched KEGG pathway analysis by the comparative transcriptomic analysis of Mro-IR knockdown ENSG00000109163 ENSG00000171105 ENSG00000130164 ENSG00000110395 ENSG00000104044 ENSG00000138798 ENSG00000198793 ENSG00000146648 ENSG00000024422 PMC4389579__F1 Conceptual model of general lifestyle factors, salient CHD pathogenetic pathways and CHD hallmarks ENSG00000162711 ENSG00000162692 ENSG00000005381 PMC4509079__F1 BMI-1 is important in the regulation of cancer and CSCs, functioning through the activation of multiple signaling pathways ENSG00000168283 ENSG00000101115 ENSG00000136997 PMC8038495__F9 Proposed scenario of the altered mechanisms driven by HFD/IPA treatment ENSG00000147162 ENSG00000198408 ENSG00000169047 PMC5799234__F1 C-type lectin receptor (CLR) signaling in fungal recognition ENSG00000162711 ENSG00000187796 ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC9105460__F1 Immunotherapy for HER2-Positive Breast Cancer: Clinical Evidence and Future Perspectives ENSG00000134982 ENSG00000163599 PMC3448082__F1 A simplified model of the feeding regulation hypothesis involving the hypothalamic neuropeptide signaling pathway ENSG00000115138 ENSG00000131096 PMC5413580__F1 Generalized schematic of checkpoint molecule structure and expression, and the balance between stimulatory and inhibitory signaling ENSG00000089692 ENSG00000198053 ENSG00000091972 ENSG00000134982 ENSG00000189403 ENSG00000163606 PMC4445746__F3 Predicted interactions between miRNA and mRNA targets within addiction relevant signaling pathways PMC8175775__F6 Identification of Tumor Necrosis Factor-Alpha (TNFA) Inhibitor in Rheumatoid Arthritis Using Network Pharmacology and Molecular Docking ENSG00000102871 ENSG00000168040 PMC2705893__F1 Protein kinase Cι: human oncogene, prognostic marker and therapeutic target ENSG00000019991 ENSG00000002330 ENSG00000291971 ENSG00000149269 ENSG00000138798 ENSG00000136997 ENSG00000146648 PMC6030972__F6 Interactive KEGG diagram for Signaling pathways regulating pluripotency of stem cells ENSG00000071564 ENSG00000002330 ENSG00000042832 ENSG00000198517 ENSG00000105656 PMC4558313__F4 Calcium homeostasis and organelle function in the pathogenesis of obesity and diabetes ENSG00000156026 ENSG00000173599 ENSG00000160741 PMC5992426__F2 Venues of prenatal alcohol exposure (PAE) altering neuroinflammation ENSG00000108691 ENSG00000125538 ENSG00000136869 ENSG00000131095 ENSG00000162692 ENSG00000121807 PMC9412785__F1 RAS signalling pathway and therapeutic approaches to target this pathway in cancer ENSG00000135446 ENSG00000115904 ENSG00000087586 ENSG00000100485 PMC5108086__F3 Toll-like receptor signaling pathway color-tagged by co-morbidity findings ENSG00000174125 ENSG00000070831 ENSG00000168040 ENSG00000150455 ENSG00000143387 ENSG00000169291 ENSG00000069482 ENSG00000156299 ENSG00000170458 ENSG00000113520 ENSG00000136869 ENSG00000131323 ENSG00000113263 PMC8864228__F2 Ion Channel Dysfunction in Astrocytes in Neurodegenerative Diseases ENSG00000125538 ENSG00000103569 ENSG00000047936 ENSG00000171885 PMC8003205__F2 CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 screens identified genes involved in Gb3 biosynthesis, with a schematic diagram of the Gb3 biosynthesis pathway and a summary of the top genes identified in CRISPR/Cas9 screens ENSG00000134851 ENSG00000119537 ENSG00000158470 ENSG00000148154 ENSG00000292209 ENSG00000106546 PMC7370165__F7 M2 polarization of tumor‐associated macrophages is dependent on integrin B3 via peroxisome proliferator‐activated receptor‐G up‐regulation in breast cancer ENSG00000135218 ENSG00000169710 PMC6061668__F1 Endothelial injury pathways in thrombotic microangiopathies ENSG00000110799 ENSG00000000971 ENSG00000162692 ENSG00000005381 PMC3322527__F7 TGFB signaling pathway overlaid with differentially expressed genes ENSG00000157933 ENSG00000133937 ENSG00000156574 PMC7479667__F3 Indirect and metabolic effects of stress on T cells ENSG00000198793 PMC5038883__F6 Proposed mechanism by which V8 induces apoptotic cell death in human multiple myeloma RPMI 8226 cells ENSG00000128272 ENSG00000144895 PMC4738049__F2 Primary Immunodeficiencies and Inflammatory Disease: A Growing Genetic Intersection ENSG00000105397 ENSG00000103522 ENSG00000105639 ENSG00000175097 PMC4549294__F14 UVB-Stimulated Expression of Transglutaminase 1 Is Mediated Predominantly via the NFKB Signaling Pathway: New Evidence of Its Significant Attenuation through the Specific Interruption of the p38/MSK1/NFKBp65 Ser276 Axis ENSG00000175104 ENSG00000146648 PMC6335097__F9 Simplified signaling pathway for vasopressin-mediated sodium-chloride cotransporter (NCC) regulation in distal convoluted tubule (DCT) cells ENSG00000143867 ENSG00000118515 PMC6519110__F1 Intracellular NAD+ metabolism in eukaryotic cells ENSG00000105835 ENSG00000172890 ENSG00000291814 ENSG00000152620 ENSG00000278488 ENSG00000157064 ENSG00000173614 PMC3423373__F3 Transcriptional Programs Controlling Perinatal Lung Maturation ENSG00000070193 ENSG00000173482 ENSG00000119969 ENSG00000127528 ENSG00000178104 ENSG00000091651 ENSG00000160783 ENSG00000164104 ENSG00000104177 ENSG00000183765 ENSG00000197273 ENSG00000180353 ENSG00000138778 ENSG00000181090 ENSG00000278494 ENSG00000136842 ENSG00000179348 ENSG00000139687 ENSG00000120837 ENSG00000119535 ENSG00000107175 ENSG00000043591 ENSG00000117399 ENSG00000132170 ENSG00000139618 ENSG00000164736 ENSG00000156127 ENSG00000132646 ENSG00000146648 ENSG00000130726 ENSG00000100234 ENSG00000123416 ENSG00000139567 ENSG00000130522 ENSG00000181104 ENSG00000142733 ENSG00000112715 ENSG00000112312 ENSG00000106546 ENSG00000137801 ENSG00000173894 ENSG00000117525 ENSG00000112242 ENSG00000128052 ENSG00000115942 ENSG00000189403 ENSG00000123374 ENSG00000122565 ENSG00000124795 ENSG00000026103 ENSG00000114346 ENSG00000113070 ENSG00000197905 ENSG00000169242 ENSG00000149311 ENSG00000186716 ENSG00000197299 ENSG00000149554 ENSG00000204217 PMC4657041__F9 The role, mechanism and potentially novel biomarker of microRNA-17-92 cluster in macrosomia ENSG00000139687 ENSG00000113360 PMC7721010__F8 Schematic regulation mechanism of miR-361-3p on lymphoma cell behaviors ENSG00000168036 PMC6029413__F2 Multiple roles of the extracellular matrix (ECM) in modulating the cancer-immunity cycle ENSG00000038427 ENSG00000126353 PMC7738607__F2 Skin immune response in dermatophytosis ENSG00000162594 ENSG00000162711 ENSG00000111537 ENSG00000187796 ENSG00000163739 ENSG00000138798 ENSG00000125538 ENSG00000169429 ENSG00000177663 ENSG00000168610 ENSG00000146648 PMC4075065__F1 Insulin/mTOR signaling pathway and also the extrinsic modifiers that are present in diabetes ENSG00000117020 ENSG00000169047 ENSG00000198793 ENSG00000133124 PMC6027159__F11 cGAS/STING signaling pathway ENSG00000164430 ENSG00000119401 ENSG00000169871 PMC6027159__F12 TCR signaling pathway ENSG00000036672 ENSG00000157625 ENSG00000175104 PMC6027159__F10 RIG-I/MAVS signaling pathway ENSG00000088888 ENSG00000082512 ENSG00000157625 ENSG00000175104 ENSG00000127191 ENSG00000121060 PMC3376961__F1 Annexin A2 pathway in pancreatic cancer invasion and metastasis ENSG00000182718 ENSG00000163914 PMC2908610__F1 Death receptor pathway via Fas ligand and Fas receptor ENSG00000168040 ENSG00000026103 PMC5571522__F7 Diagram of CPT inhibiting IGF‐1/AKT/mTOR pathway via suppressing the ERA in breast cancer ENSG00000169047 ENSG00000140443 PMC6027159__F13 Genotoxic stress signaling pathway ENSG00000149311 ENSG00000137275 ENSG00000157625 ENSG00000175104 PMC9482139__F2 Energy metabolism pathways in breast cancer progression: The reprogramming, crosstalk, and potential therapeutic targets ENSG00000159399 PMC12110588__F3 Structure, conserved motifs, and anti-interferon activities of programmed death-1 ligand 1 ENSG00000168610 PMC6995521__F7 Differentially expressed proteins in the Cyp27a1−/−Cyp46a1−/−Soat1−/− vs ENSG00000291507 ENSG00000137274 ENSG00000109270 PMC2715971__F2 Interaction between insulin and interferon-alfa signaling pathway ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC9482139__F1 Energy metabolism pathways in breast cancer progression: The reprogramming, crosstalk, and potential therapeutic targets ENSG00000092621 ENSG00000169710 ENSG00000146733 ENSG00000115419 PMC6626719__F3 Aberrant activation of the Wnt/Beta-catenin signaling pathway in hepatocellular carcinoma ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000084774 PMC6838672__F3 High-Throughput Assessment of Kinome-wide Activation States ENSG00000136807 ENSG00000087095 ENSG00000110721 ENSG00000157764 ENSG00000070831 ENSG00000178573 PMC7226390__F7 Schematic abstract of the oncogenic and CSCs-promoting role of MALAT1 in HCC ENSG00000122691 ENSG00000168036 ENSG00000168610 PMC6520011__F1 Impaired ribosome biogenesis ENSG00000101751 PMC8022952__F1 Expected flavonoid biosynthesis pathway in maize ENSG00000166278 PMC3757426__F1 Epidermal growth factor receptor (EGFR) crosstalk ENSG00000065361 ENSG00000291971 ENSG00000146648 ENSG00000178568 ENSG00000140443 PMC9506007__F2 Regulation Mechanism of Plant Pigments Biosynthesis: Anthocyanins, Carotenoids, and Betalains ENSG00000173599 PMC4792076__F7 Schematic view of B3 integrin–GSK3B and BMP-2–Smad cooperation ENSG00000170365 ENSG00000291971 PMC10993494__F9 Extracellular vesicles-coupled miRNAs from oviduct and uterus modulate signaling pathways related to lipid metabolism and bovine early embryo development ENSG00000140564 ENSG00000135218 ENSG00000070831 ENSG00000105329 ENSG00000148926 ENSG00000186480 ENSG00000169710 ENSG00000111229 ENSG00000245848 ENSG00000172216 ENSG00000082175 ENSG00000170522 ENSG00000110148 ENSG00000149968 ENSG00000266173 ENSG00000090686 ENSG00000150907 ENSG00000125538 ENSG00000285390 ENSG00000163449 ENSG00000169429 ENSG00000185591 ENSG00000152926 ENSG00000177666 ENSG00000100344 ENSG00000168040 ENSG00000076555 ENSG00000073756 ENSG00000277943 ENSG00000007171 ENSG00000132170 ENSG00000167772 ENSG00000281614 ENSG00000111537 ENSG00000036530 ENSG00000149485 ENSG00000140285 ENSG00000172936 ENSG00000005381 PMC7910618__F4 Cancer-associated fibroblast-derived SDF-1 induces epithelial-mesenchymal transition of lung adenocarcinoma via CXCR4/Beta-catenin/PPARD signalling ENSG00000168036 ENSG00000121966 PMC3368988__F2 Sites of PP2A activity within the network of ERK activation ENSG00000291971 ENSG00000141068 PMC138773__F1 EGFR transactivation by GPCRs and cytokine receptors ENSG00000291971 ENSG00000146648 PMC5439543__F1 CHEK2 pathway ENSG00000149311 ENSG00000012048 ENSG00000119408 ENSG00000101224 ENSG00000139618 PMC5644640__F1 Summary of potential beta adrenergic signaling pathways in canine hemangiosarcoma and human angiosarcoma ENSG00000291971 ENSG00000100985 ENSG00000073756 PMC4407294__F1 PI3K/AKT/mTOR and the RAS/RAF/MEK/MAPK pathways ENSG00000150907 ENSG00000105723 PMC4407294__F2 Molecular pathways regulating breast cancer stem cells (CSCs) ENSG00000163464 ENSG00000291971 ENSG00000173039 ENSG00000168036 ENSG00000128602 ENSG00000168610 ENSG00000146648 PMC4754414__F1 Pathways for molecular targeting in prostate cancer radiotherapy ENSG00000149311 ENSG00000175054 ENSG00000185379 ENSG00000198793 ENSG00000051180 ENSG00000139618 PMC2729812__F1 Proposed pathway from pressure overload to LV hypertrophy and fibrosis ENSG00000163235 ENSG00000113070 ENSG00000148848 PMC10506215__F3 PTM of PGK1, including acetylation, phosphorylation, ubiquitination and O-GlcNAcylation ENSG00000171720 ENSG00000198793 PMC2908510__F3 Normal and Cancer-Related Functions of the p160 Steroid Receptor Coactivator (SRC) Family ENSG00000033327 ENSG00000169047 ENSG00000146648 PMC8010917__F2 NLRP3 activation pathway ENSG00000162711 ENSG00000125538 ENSG00000172936 PMC4029299__F3 Gene- and pathway-based connectivity map of vismodegib and Gorlin syndrome ENSG00000117425 ENSG00000128602 PMC4455035__F2 Pericytes, microvasular dysfunction and chronic rejection ENSG00000167772 PMC8036964__F7 Target-enriched KEGG pathway network for UR alkaloids against AD ENSG00000143799 ENSG00000157404 ENSG00000198793 ENSG00000087085 ENSG00000164305 ENSG00000149295 ENSG00000276825 ENSG00000133019 ENSG00000184845 ENSG00000143801 ENSG00000138613 ENSG00000196549 ENSG00000149968 ENSG00000205155 ENSG00000165646 ENSG00000077782 ENSG00000275565 ENSG00000276996 ENSG00000186297 ENSG00000182578 ENSG00000087245 ENSG00000171105 ENSG00000158748 ENSG00000089041 ENSG00000073756 ENSG00000102468 ENSG00000007171 ENSG00000010810 ENSG00000148680 ENSG00000100985 ENSG00000113448 PMC11848799__F2 Monocyte eukaryotic initiation factor 2 signaling differentiates 17-hydroxy-docosahexaenoic acid levels and pain ENSG00000070756 ENSG00000084093 ENSG00000144895 ENSG00000172005 ENSG00000100842 PMC11933059__F2 PAM pathway mechanism of action ENSG00000135446 ENSG00000105810 PMC8953665__F4 Cholesterol metabolism: from lipidomics to immunology ENSG00000007944 ENSG00000057252 ENSG00000138075 ENSG00000130208 ENSG00000112972 ENSG00000172893 ENSG00000113161 ENSG00000167780 ENSG00000130164 ENSG00000116133 ENSG00000160179 ENSG00000267467 ENSG00000143921 PMC1413813__F8 The signaling pathway regulating the expressions of SMAlpha-actin, SM-MHC, and calponin in SMCs on polymerized collagen in response to PDGF-BB/IL-1B costimulation ENSG00000198793 ENSG00000115594 PMC8953665__F1 Cholesterol metabolism: from lipidomics to immunology ENSG00000057252 ENSG00000138135 ENSG00000115415 ENSG00000107798 ENSG00000125538 ENSG00000136869 ENSG00000164342 ENSG00000135929 PMC6705791__F5 Proteome-transcriptome alignment of molecular portraits achieved by self-contained gene set analysis: Consensus colon cancer subtypes case study ENSG00000148926 ENSG00000099194 ENSG00000113790 ENSG00000123983 PMC6705791__F6 Proteome-transcriptome alignment of molecular portraits achieved by self-contained gene set analysis: Consensus colon cancer subtypes case study ENSG00000019582 ENSG00000231021 ENSG00000276051 ENSG00000232326 ENSG00000175899 ENSG00000277263 ENSG00000273686 ENSG00000231925 PMC4293272__F2 Cell Signaling Pathways Involved in Hematopoietic Stem Cell Specification ENSG00000170365 ENSG00000148400 ENSG00000168036 ENSG00000002745 ENSG00000112715 PMC4729769__F7 Schematic Diagram Depicting the Proposed Role of P-gp in the Formation of Peritoneal Adhesions following an Abdominal Operation ENSG00000105329 PMC5095004__F9 MicroRNA-126 induces autophagy by altering cell metabolism in malignant mesothelioma ENSG00000177169 ENSG00000198793 ENSG00000172005 ENSG00000026103 PMC9354322__F3 Pleiotropic roles of cGAS–STING signaling in the tumor microenvironment ENSG00000101751 ENSG00000184995 PMC8304710__F2 Hypoxia, Metabolic Reprogramming, and Drug Resistance in Liver Cancer ENSG00000185633 ENSG00000065911 ENSG00000074800 ENSG00000092621 ENSG00000158828 ENSG00000146733 ENSG00000159399 ENSG00000120254 PMC4563985__F3 Proposed mechanisms of activation of proinflammatory signaling pathways in IFN-mediated autoinflammatory diseases ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000276561 PMC4177461__F2 Helicobacter pylori mediated downregulation of B7-H2 on gastric epithelial cell inhibits Th17 cell development and facilitates bacterial persistence ENSG00000198793 PMC5983750__F1 Molecular pathways involved in senescence ENSG00000149311 ENSG00000115008 ENSG00000198793 PMC3479314__F1 SHEDDING NEW LIGHT ON NEURODEGENERATIVE DISEASES THROUGH THE MAMMALIAN TARGET OF RAPAMYCIN ENSG00000198793 ENSG00000155792 ENSG00000167965 PMC9530903__F6 Metabolome and transcriptome association analysis revealed key factors involved in melatonin mediated cadmium-stress tolerance in cotton ENSG00000113492 ENSG00000137992 ENSG00000128928 ENSG00000091140 PMC3811932__F1 Growth factors, insulin, nutrients and energy status regulate the activation of the PI3K/Akt/mTOR signaling network ENSG00000011566 ENSG00000002330 ENSG00000169047 ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC9442330__F2 Peroxisomal regulation of energy homeostasis: Effect on obesity and related metabolic disorders ENSG00000176894 ENSG00000018510 ENSG00000173599 ENSG00000198670 ENSG00000116906 ENSG00000109016 PMC6473256__F8 Cilia-dependent and independent activation of Gli proteins ENSG00000205927 ENSG00000164690 ENSG00000128602 PMC12052750__F4 Gut microbiome imbalance disrupts the gut-lung axis ENSG00000162711 ENSG00000111537 ENSG00000125538 PMC8117532__F6 Role of chimeric genes in pathway-related gene co-expression modules ENSG00000134982 PMC3756172__F1 Summary of AERD associated single nucleotide polymorphisms in the genes of immune response and arachidonate pathway ENSG00000149451 ENSG00000162711 ENSG00000283887 ENSG00000050628 ENSG00000160013 ENSG00000130433 ENSG00000112499 ENSG00000125384 ENSG00000112562 ENSG00000132170 ENSG00000170458 ENSG00000113520 ENSG00000136869 ENSG00000291905 ENSG00000111181 ENSG00000185591 ENSG00000102104 ENSG00000113525 ENSG00000164342 PMC3196377__F6 Regulator of G Protein Signaling 6 (RGS6) Mediates Doxorubicin-induced ATM and p53 Activation by a Reactive Oxygen Species (ROS)-dependent Mechanism ENSG00000149311 PMC4032668__F3 Simplified scheme of the DAF-16 signalling pathway in C ENSG00000118515 PMC4846574__F12 P21-activated kinase, PAK2, is important in the activation of numerous pancreatic acinar cell signaling cascades and in the onset of early pancreatitis events ENSG00000070831 ENSG00000291971 PMC8151260__F1 Deregulation of the Interleukin-7 Signaling Pathway in Lymphoid Malignancies ENSG00000099985 ENSG00000114737 ENSG00000136997 ENSG00000137193 ENSG00000171791 ENSG00000105639 PMC4192477__F2 Numerous proteins that interact with core components of the NOD2 and MAPK signaling pathways were identified as regulators of IL-8 secretion ENSG00000137713 ENSG00000109332 ENSG00000167207 ENSG00000140044 ENSG00000158517 ENSG00000185651 ENSG00000012048 ENSG00000129219 ENSG00000088888 ENSG00000078747 ENSG00000124523 ENSG00000140464 ENSG00000169375 ENSG00000166167 ENSG00000173039 ENSG00000132357 ENSG00000285152 ENSG00000146243 ENSG00000108465 ENSG00000105568 ENSG00000169019 ENSG00000103404 ENSG00000149311 ENSG00000127445 ENSG00000163435 ENSG00000124216 ENSG00000102034 ENSG00000143507 ENSG00000164362 ENSG00000126895 ENSG00000105483 ENSG00000084774 PMC3081368__F8 HMGB factors are required for posterior digit development through integrating signaling pathway activities ENSG00000168036 ENSG00000189403 ENSG00000164690 ENSG00000164104 PMC6156463__F2 Metabolism of SAM ENSG00000198793 ENSG00000099810 PMC2731678__F3 PAK Signaling in Oncogenesis ENSG00000002330 PMC6156463__F5 Distinct metabolic pathways in cancer cells and their connection to epigenetic modifications ENSG00000131473 ENSG00000105835 ENSG00000198793 ENSG00000099810 ENSG00000198734 ENSG00000124253 ENSG00000146701 ENSG00000115419 ENSG00000159399 PMC3911500__F7 Schematic model for how S6K1 inhibits TLR2- or TLR4-mediated signaling pathways ENSG00000136869 ENSG00000175104 PMC6999456__F2 Sketches for DCA synthetic pathways ENSG00000039537 ENSG00000113600 ENSG00000026103 PMC1664664__F2 Neurotrophin signalling ENSG00000163914 ENSG00000177606 PMC5010673__F2 Summary of interactions involved in Wnt signaling cascades inferred to regulate NC biological functions ENSG00000004975 ENSG00000112576 ENSG00000166167 ENSG00000107404 ENSG00000156076 ENSG00000178585 ENSG00000134982 ENSG00000095015 ENSG00000168036 ENSG00000175029 ENSG00000118971 ENSG00000140807 ENSG00000284984 ENSG00000171016 ENSG00000065717 ENSG00000163904 ENSG00000100592 ENSG00000177606 ENSG00000136997 ENSG00000047849 ENSG00000150630 PMC4563985__F4 Mechanisms of NFKB-mediated diseases ENSG00000141527 ENSG00000088888 ENSG00000167207 ENSG00000157625 PMC6314674__F1 Metabolic pathways controlling macrophage activation states ENSG00000260314 ENSG00000111537 ENSG00000011028 ENSG00000118520 ENSG00000026103 PMC4644679__F1 Hippo signaling pathway and main regulators ENSG00000186575 ENSG00000109321 ENSG00000089685 ENSG00000144560 ENSG00000163914 ENSG00000136997 ENSG00000168036 ENSG00000168646 PMC4574066__F2 Downstream analysis of Wnt-related gene expression from aged animals predicts a decrease in cell viability and transcription of RNA ENSG00000115008 ENSG00000173039 ENSG00000175592 ENSG00000150782 ENSG00000157557 ENSG00000108691 ENSG00000151778 ENSG00000125398 ENSG00000136997 ENSG00000113520 ENSG00000136869 ENSG00000128342 ENSG00000164690 ENSG00000146648 ENSG00000184216 PMC4911124__F8 Influenza A Virus Challenge Models in Cynomolgus Macaques Using the Authentic Inhaled Aerosol and Intra-Nasal Routes of Infection ENSG00000173372 ENSG00000133110 ENSG00000104969 ENSG00000168878 ENSG00000197451 ENSG00000172183 PMC5745765__F12 Design of disease network based on mRNA expression analysis and effects of cytokines, chemokines and growth factors described in the literature ENSG00000019991 ENSG00000111537 ENSG00000105329 ENSG00000137033 ENSG00000158477 ENSG00000145777 PMC6279911__F1 MiRNA targets in teleost fish immune system ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000276561 PMC5745765__F10 Design of disease network based on mRNA expression analysis and effects of cytokines, chemokines and growth factors described in the literature ENSG00000019991 ENSG00000111537 ENSG00000105329 ENSG00000137033 ENSG00000158477 ENSG00000145777 PMC5745765__F11 Design of disease network based on mRNA expression analysis and effects of cytokines, chemokines and growth factors described in the literature ENSG00000019991 ENSG00000111537 ENSG00000105329 ENSG00000137033 ENSG00000158477 ENSG00000145777 PMC3137710__F2 Chemical ‘Jekyll and Hyde’s: Small-molecule inhibitors of developmental signaling pathways ENSG00000134982 ENSG00000107854 ENSG00000168036 ENSG00000168646 PMC4931673__F3 Circuitry of amino acid signalling to MTORC1 ENSG00000143761 ENSG00000130147 ENSG00000198793 ENSG00000145979 ENSG00000052795 ENSG00000167965 PMC8392360__F1 PI3K/Akt Pathway: The Indestructible Role of a Vintage Target as a Support to the Most Recent Immunotherapeutic Approaches ENSG00000111537 ENSG00000198793 PMC8392360__F2 PI3K/Akt Pathway: The Indestructible Role of a Vintage Target as a Support to the Most Recent Immunotherapeutic Approaches ENSG00000157764 ENSG00000163599 ENSG00000010671 PMC5814187__F8 Dock derived compound against laminin receptor (37 LR) exhibits anti-cancer properties in a prostate cancer cell line model ENSG00000182481 ENSG00000167996 ENSG00000198554 ENSG00000112118 ENSG00000076003 ENSG00000070669 ENSG00000108106 PMC4189494__F6 Schematic representation of the negative regulation of TLR3 and TLR5 signaling by MUC1 ENSG00000187554 ENSG00000172936 ENSG00000164342 PMC6850916__F7 Inhibition of leucocyte migration was included in early moderate exercise‐mediated improvement of inflammation ENSG00000204577 ENSG00000154639 ENSG00000150455 ENSG00000137801 ENSG00000224320 ENSG00000136997 ENSG00000108405 ENSG00000113749 ENSG00000168484 ENSG00000271447 ENSG00000186912 ENSG00000275565 ENSG00000291368 PMC3109866__F1 Converging Pathways in Lifespan Regulation ENSG00000118515 ENSG00000164327 PMC2881822__F8 ERB Impedes Prostate Cancer EMT by Destabilizing HIF-1A and Inhibiting VEGF-Mediated Snail Nuclear Localization: Implications for Gleason Grading ENSG00000112715 PMC6167544__F8 Cellar signal transduction pathway induced by GALT ENSG00000142192 ENSG00000125538 ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC5061784__F3 HER2/PI3K/PTEN/Akt/mTORC pathway and potential sites for intervention with small molecule membrane‐permeable inhibitors and monoclonal antibodies (MoAbs) ENSG00000177169 ENSG00000198793 ENSG00000169047 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC6110865__F6 KLHDC7B and the Interferon signaling pathway ENSG00000068079 ENSG00000213928 ENSG00000111537 ENSG00000115415 ENSG00000033800 ENSG00000185745 ENSG00000125347 ENSG00000276561 PMC5839951__F1 IGF-1 signaling mediated cell-specific skeletal mechano-transduction ENSG00000178860 ENSG00000167941 ENSG00000198793 ENSG00000168646 ENSG00000140443 PMC6943569__F4 Activation of NF-кB by the canonical and/or the noncanonical pathway ENSG00000104856 ENSG00000173039 ENSG00000162924 PMC6567082__F1 Crocus sativus extract affects the cell cycle by blocking the G2 and S phase via p53 and CyclinB-cdk2 proteins ENSG00000171791 ENSG00000101224 PMC5645510__F2 KEGG pathway “FOXO signaling pathway” is regulated by let-7 miRNA ENSG00000145604 ENSG00000149311 ENSG00000087095 ENSG00000171105 ENSG00000138798 ENSG00000127528 ENSG00000123374 PMC12087082__F4 Purine metabolic pathway ENSG00000156110 ENSG00000140505 ENSG00000198931 ENSG00000136448 ENSG00000152465 PMC3235480__F2 RAF/MEK/ERK and the PI3K/AKT/mTOR signaling pathways are shown ENSG00000002330 ENSG00000198793 PMC7564661__F4 Membrane damage signaling ENSG00000162711 ENSG00000125538 ENSG00000265972 ENSG00000221926 PMC5383353__F1 IRS4 signaling in malignant cells and therapy resistance ENSG00000169047 ENSG00000158458 ENSG00000133124 PMC4652402__F2 Linear Motifs in T cell receptor signalling pathway hsa04660 ENSG00000291603 ENSG00000111537 ENSG00000110395 ENSG00000213658 ENSG00000070831 ENSG00000010810 ENSG00000163914 ENSG00000113520 ENSG00000113263 PMC4516574__F11 Hypothetical model illustrating p53 transgene mediated inhibition of Type I IFN signaling during VSV infection ENSG00000105397 ENSG00000115415 PMC9657855__F9 Storax Attenuates Cardiac Fibrosis following Acute Myocardial Infarction in Rats via Suppression of AT1R–Ankrd1–P53 Signaling Pathway PMC6121259__F5 Signaling pathways involved in TNF/Thy-1-induced astrocyte polarization and migration ENSG00000291971 ENSG00000154096 PMC9354322__F1 Pleiotropic roles of cGAS–STING signaling in the tumor microenvironment ENSG00000213928 ENSG00000164430 ENSG00000105397 ENSG00000168610 PMC12216578__F4 Effect of PM2 ENSG00000213658 ENSG00000163914 ENSG00000077782 ENSG00000084774 PMC11796190__F7 Diagram highlights the distinct mechanisms by which EA and MA modulate hypothalamic function in PCOS ENSG00000150093 PMC8431827__F2 Immunomodulatory Properties of Biologically Active Components of Spices Against SARS-CoV-2 and Pan Beta-Coronaviruses ENSG00000108691 ENSG00000116044 ENSG00000169429 PMC4317626__F1 Complement activation pathways ENSG00000117335 ENSG00000166278 PMC10242860__F4 Ferritin in cancer therapy: A pleiotropic tumoraffin nanocage‐based transport ENSG00000183735 ENSG00000239732 PMC7664177__F2 Canonical Pathway of NFKB which represents the pro-inflammatory response, and Keap-Nrf2-ARE Pathway which represents anti-inflammatory response ENSG00000178573 ENSG00000079999 PMC4149376__F8 Wnts Enhance Neurotrophin-Induced Neuronal Differentiation in Adult Bone-Marrow-Derived Mesenchymal Stem Cells via Canonical and Noncanonical Signaling Pathways ENSG00000154764 ENSG00000164061 ENSG00000123454 ENSG00000168036 ENSG00000106483 PMC4892113__F4 Role of Spermidine-TCPTP in the complex dynamics of pro- and anti-autophagic factors ENSG00000149311 ENSG00000177169 ENSG00000146648 PMC9138936__F4 Autophagy Modulation in Aggresome Formation: Emerging Implications and Treatments of Alzheimer’s Disease ENSG00000094631 ENSG00000198382 PMC8276693__F2 Tumor Microenvironment Factors That Promote Resistance to Immune Checkpoint Blockade Therapy ENSG00000111537 ENSG00000115415 ENSG00000134982 ENSG00000125347 PMC4480265__F2 Sensing of cell death by myeloid C-type lectin receptors ENSG00000081041 ENSG00000187796 ENSG00000163739 PMC8253910__F5 Normothermic Ex-vivo Kidney Perfusion in a Porcine Auto-Transplantation Model Preserves the Expression of Key Mitochondrial Proteins: An Unbiased Proteomics Analysis ENSG00000140319 ENSG00000067836 ENSG00000113597 ENSG00000143158 ENSG00000082397 ENSG00000138079 ENSG00000085982 ENSG00000167363 ENSG00000107798 ENSG00000144827 ENSG00000090621 ENSG00000143198 ENSG00000038219 ENSG00000070610 ENSG00000163528 ENSG00000074276 ENSG00000116039 ENSG00000115841 ENSG00000288191 ENSG00000184999 ENSG00000109819 ENSG00000157184 ENSG00000181404 ENSG00000196549 ENSG00000100412 ENSG00000241935 ENSG00000140465 ENSG00000186526 ENSG00000132170 ENSG00000115875 ENSG00000148702 ENSG00000120594 ENSG00000105379 ENSG00000104325 ENSG00000175792 PMC9038420__F2 Effects of Nrf2 in Exercise Intervention of Neurotoxicity Caused by Methamphetamine Oxidative Stress ENSG00000100387 ENSG00000079999 PMC6277552__F1 Iron metabolism in prostate cancer microenvironment ENSG00000188992 PMC2674123__F10 Signaling cascade of PI3K/AKT pathway ENSG00000033327 ENSG00000002330 ENSG00000105401 ENSG00000198793 PMC11023972__F3 DDR components regulate cytosolic RNA sensors-dependent IFNs and NFKB signaling pathways ENSG00000149311 ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000276561 PMC11023972__F4 DDR components regulate NFKB signaling pathways ENSG00000149311 ENSG00000239732 ENSG00000172936 ENSG00000175104 ENSG00000276561 PMC11023972__F1 DNA-damage response pathways ENSG00000188486 ENSG00000164053 ENSG00000149311 ENSG00000175054 ENSG00000004700 ENSG00000276618 ENSG00000134574 ENSG00000165392 ENSG00000170430 ENSG00000167986 ENSG00000197299 ENSG00000051180 ENSG00000177084 ENSG00000136936 PMC11023972__F2 DDR components regulate IFNs signaling pathways ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000141867 ENSG00000183735 ENSG00000164430 ENSG00000144554 ENSG00000163565 ENSG00000197299 ENSG00000051180 ENSG00000139618 PMC4926799__F3 Summary of the mechanisms by which stress-related immune alterations may precipitate depression ENSG00000125538 ENSG00000132478 PMC11023972__F5 DDR components regulate JAK-STAT signaling pathways ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000197299 ENSG00000142166 PMC10500222__F1 CELF2 affects ferroptosis through the MAPK signalling pathway ENSG00000179148 ENSG00000092470 ENSG00000151012 ENSG00000167468 ENSG00000072274 ENSG00000165527 ENSG00000131196 ENSG00000115419 ENSG00000048740 PMC4573837__F1 Phase I study of the mTOR inhibitor ridaforolimus and the HDAC inhibitor vorinostat in advanced renal cell carcinoma and other solid tumors ENSG00000198793 ENSG00000164327 PMC10500222__F2 CELF2 affects ferroptosis through the PI3K/AKT signalling pathway ENSG00000151012 ENSG00000125144 ENSG00000181019 ENSG00000010810 ENSG00000167468 ENSG00000198793 ENSG00000167996 ENSG00000187840 ENSG00000048740 PMC7892952__F1 Adenine-based purines are ubiquitous compounds present at intra- and intracellular levels in normal (i.e., astrocytes) and tumoral (i.e., GSCs) cells PMC4748411__F4 Differential Expression of Genes and DNA Methylation associated with Prenatal Protein Undernutrition by Albumen Removal in an avian model ENSG00000113369 ENSG00000102891 ENSG00000147381 ENSG00000135678 PMC7398916__F5 BCR Signaling Pathway with FCRL genes ENSG00000140992 ENSG00000070190 ENSG00000095585 ENSG00000177455 ENSG00000180353 ENSG00000107263 ENSG00000150907 ENSG00000136997 ENSG00000197943 ENSG00000160293 ENSG00000213341 ENSG00000152689 ENSG00000110395 ENSG00000135605 ENSG00000033327 ENSG00000070831 ENSG00000115904 ENSG00000110651 ENSG00000099942 ENSG00000141968 ENSG00000010671 ENSG00000112242 ENSG00000143398 ENSG00000137265 ENSG00000160856 ENSG00000143297 ENSG00000291761 ENSG00000072135 ENSG00000124181 ENSG00000086730 ENSG00000198286 ENSG00000104365 ENSG00000105369 ENSG00000157764 ENSG00000100906 ENSG00000109320 ENSG00000007312 ENSG00000269335 ENSG00000173039 ENSG00000281877 ENSG00000186111 ENSG00000162924 ENSG00000143933 ENSG00000081189 ENSG00000160691 ENSG00000120910 ENSG00000281614 ENSG00000010810 ENSG00000177606 ENSG00000154059 ENSG00000105723 PMC3968564__F1 1A: Base excision repair (BER) pathway targets DNA damaged during replication or by environmental agents ENSG00000012061 ENSG00000185379 ENSG00000182185 ENSG00000108384 ENSG00000136936 PMC6466823__F4 Main pathways and respective genes found in different treatments of ECs ENSG00000030582 ENSG00000070831 ENSG00000101000 ENSG00000168036 ENSG00000010278 ENSG00000196396 ENSG00000005893 ENSG00000119655 ENSG00000148175 ENSG00000136026 ENSG00000277263 ENSG00000138119 ENSG00000084733 ENSG00000119396 ENSG00000111142 ENSG00000253729 ENSG00000172380 ENSG00000078369 ENSG00000198561 ENSG00000173039 ENSG00000076706 ENSG00000127022 ENSG00000163661 ENSG00000224320 ENSG00000026508 ENSG00000103769 PMC6376179__F4 Mutations in key pathways controlling cell growth ENSG00000104365 ENSG00000157764 ENSG00000065361 ENSG00000095015 ENSG00000135111 ENSG00000105639 ENSG00000118971 ENSG00000168610 ENSG00000149311 ENSG00000117020 ENSG00000159216 ENSG00000107485 ENSG00000077782 ENSG00000139687 ENSG00000146648 ENSG00000196712 ENSG00000140443 PMC4677035__F6 FcGR-mediated phagocytosis pathway in the KEGG database is the putative pathway which is related to TNFA and TGFB1 expression in microglial cells ENSG00000033327 ENSG00000213658 PMC10500222__F5 CELF2 affects ferroptosis via the Wnt/Beta-catenin pathway ENSG00000281324 ENSG00000149269 ENSG00000167468 ENSG00000168036 ENSG00000048740 PMC10420029__F8 Transcription related pathways in the seminal tissues of P ENSG00000111581 ENSG00000124789 ENSG00000086589 ENSG00000277273 ENSG00000134480 ENSG00000166337 ENSG00000130699 ENSG00000171540 ENSG00000213024 ENSG00000164609 ENSG00000178913 ENSG00000021776 ENSG00000120656 ENSG00000138750 ENSG00000120690 ENSG00000102900 ENSG00000095319 ENSG00000276463 ENSG00000160799 ENSG00000172239 ENSG00000153201 ENSG00000169251 ENSG00000126883 ENSG00000179950 ENSG00000197780 ENSG00000276833 ENSG00000155561 ENSG00000124380 ENSG00000196313 ENSG00000064995 ENSG00000131652 ENSG00000162385 ENSG00000085872 ENSG00000165632 ENSG00000102034 ENSG00000164902 ENSG00000163634 ENSG00000125450 ENSG00000132341 PMC10500222__F6 CELF2 is the upstream regulation factor of MAPK signalling pathway, PI3K/AKT signalling pathway, autophagy and ERAD pathway, which can promote cancer cell ferroptosis through these pathways ENSG00000046889 ENSG00000131196 ENSG00000057663 ENSG00000048740 PMC7994620__F4 Activation of cyclic AMP pathway through various genetic defects in adrenocortical tumors and hyperplasias ENSG00000188191 ENSG00000128655 ENSG00000087460 PMC10928970__F1 BRAF gene signaling pathway ENSG00000113905 ENSG00000157764 ENSG00000138798 ENSG00000146648 PMC3494542__F3 TGFB non-canonical signaling pathway ENSG00000070831 ENSG00000168036 PMC5547956__F6 Transcriptome profiling of the subventricular zone and dentate gyrus in an animal model of Parkinson's disease ENSG00000087095 ENSG00000172680 ENSG00000170458 ENSG00000177606 ENSG00000130159 ENSG00000175104 ENSG00000127191 ENSG00000146648 ENSG00000026103 PMC5547956__F7 Synopsis of significant mitogen-activated protein kinase (MAPK) signaling pathway in the dentate gyrus (DG) of mice exposed to MPTP according to the Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis ENSG00000163930 ENSG00000170458 ENSG00000138798 ENSG00000177606 ENSG00000130159 ENSG00000175104 ENSG00000127191 ENSG00000146648 ENSG00000026103 PMC4319670__F1 Insulin signal transduction pathway ENSG00000124102 ENSG00000169047 PMC6029073__F1 Schematic diagram of the Sho1-dependant branch of the yeast high osmolarity glycerol (HOG) pathway as a model system for analysis of short linear motif function in signal transduction ENSG00000070831 ENSG00000069248 PMC5260495__F8 A schematic diagram shows that CD9 binds to gp130 and stabilizes gp130 by blocking its ubiquitin-dependent lysosomal degradation to promote the BMX-mediated STAT3 activation in GSCs ENSG00000133937 ENSG00000010278 ENSG00000102010 ENSG00000168610 PMC6029073__F7 Examples of well-characterized signaling pathways contain numerous predicted short linear motifs ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC10934027__F6 Metabolic pathway of terpene biosynthesis ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC5468443__F1 mTOR Signaling Pathway ENSG00000140992 ENSG00000169047 PMC6747043__F3 Endoplasmic reticulum (ER) stress-mediated inflammation ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC8517779__F1 Biomarkers for gastrointestinal adverse events related to thiopurine therapy ENSG00000137364 ENSG00000136159 PMC7552614__F10 Representation of the TGFB, BMP, and WNT signaling pathways ENSG00000198793 ENSG00000168036 PMC1409799__F4 MAPK signaling pathways ENSG00000124733 ENSG00000188404 PMC3578480__F2 Molecular pathways associated with CPPs ENSG00000122691 ENSG00000074181 PMC10572663__F2 Signaling pathways regulating EMT ENSG00000019991 ENSG00000138795 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000124216 ENSG00000122691 ENSG00000177606 ENSG00000139549 ENSG00000164690 ENSG00000128602 ENSG00000163501 PMC2855202__F3 Cross-talk between the hexosamine biosynthesis pathway, O-GlcNAc modification of proteins, signaling events downstream of insulin action, and glucose-induced adipocytokine secretion ENSG00000147162 ENSG00000198408 ENSG00000220205 ENSG00000185591 PMC10572663__F3 Hypothetical contribution of EMT-like process to the pathophysiology of RA ENSG00000159216 ENSG00000149968 ENSG00000198793 ENSG00000100985 PMC10572663__F4 Hypothetical contribution of EMT to the pathophysiology of pSS ENSG00000169554 ENSG00000105329 ENSG00000291748 ENSG00000100985 PMC3847504__F5 Schematic illustration of the correlation in mechanisms among detected parameters ENSG00000189403 ENSG00000172936 ENSG00000164342 PMC9935518__F7 Decision-making workflow for selecting treatment for newly diagnosed ER+/HER2- metastatic breast cancer patients ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000106624 PMC11858609__F6 Illustrates the MAPK and NFKB signaling pathways activated by pro-inflammatory stimuli such as LPS, IL-1, IL-26, TNFA, and PAMPs ENSG00000136869 PMC11858609__F7 Effects of bioactive compounds on periodontal bone remodeling ENSG00000131196 PMC11858609__F3 Illustrates the NFKB signaling pathway, highlighting the role of pro-inflammatory stimuli such as LPS, IL-1, IL-36, TNFA, and PAMPs, which activate receptors (TLR4, IL-1R, TNFR) to initiate intracellular signaling cascades ENSG00000137275 ENSG00000102871 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC4465296__F1 Clinical implications of miRNAs in the pathogenesis, diagnosis and therapy of pancreatic cancer ENSG00000156299 ENSG00000148798 ENSG00000175832 ENSG00000173599 PMC4465296__F3 Clinical implications of miRNAs in the pathogenesis, diagnosis and therapy of pancreatic cancer ENSG00000164690 PMC7246929__F1 Extrinsic apoptotic signaling pathway ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC7774640__F1 Cartoon proposed model of thyroid-associated ophthalmopathy (TAO) pathogenesis ENSG00000174059 PMC7471609__F3 Metabolic map visualization for (A) redox and hydrogenases pathway, (B) pyruvate node that links glycolysis, incomplete Krebs cycle, anapleurotic pathway, and fermentative pathway, and (C) sulfur metabolism using the Escher tool ENSG00000144063 ENSG00000173599 ENSG00000161513 ENSG00000084072 ENSG00000082212 ENSG00000127948 PMC8143163__F1 Impact of H2S on Obesity-Associated Metabolic Disturbances ENSG00000116761 PMC5493710__F3 Improvement of the reprogramming process and replacement of c-Myc by small molecules and chemical compounds ENSG00000154342 PMC11626610__F4 Genes from the Toll-like receptor signalling pathway remain differentially expressed 8 h post 4th dose in MAD cohorts ENSG00000174125 ENSG00000239732 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000168040 ENSG00000150455 ENSG00000276561 ENSG00000164342 ENSG00000143387 PMC3077244__F5 The proposed signalling pathway ENSG00000168036 PMC4092857__F3 Activation of the DNA damage response upon CDT exposure ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000135446 ENSG00000123374 PMC3876433__F1 Oxidative metabolism in cancer ENSG00000033327 ENSG00000291971 ENSG00000137193 ENSG00000168610 ENSG00000150630 PMC5328987__F1 Type III IFN signaling pathway ENSG00000184979 ENSG00000292250 ENSG00000105397 ENSG00000157601 ENSG00000291876 ENSG00000243646 ENSG00000291875 PMC6704952__F9 Proposed mechanisms involved in the increase of SMN expression induced by ERK inhibition in the spinal cord of severe SMA-like mice ENSG00000273772 PMC12174016__F2 Mechanism of therapeutic strategies targeting pyroptosis for AD ENSG00000278718 ENSG00000162711 ENSG00000178573 ENSG00000136869 ENSG00000265972 PMC12174016__F1 Molecular mechanism of pyroptosis ENSG00000162711 ENSG00000163568 ENSG00000091592 ENSG00000091106 PMC8712646__F1 Vitiligo: An Autoimmune Skin Disease and its Immunomodulatory Therapeutic Intervention ENSG00000169245 ENSG00000186810 ENSG00000148400 ENSG00000138755 PMC9124774__F1 Recent Advances in Dual PI3K/mTOR Inhibitors for Tumour Treatment ENSG00000198793 PMC7518314__F1 Overlap between immune-signaling genes that are associated with pollution and SCZ ENSG00000170458 ENSG00000136869 ENSG00000132693 PMC3828651__F2 Molecular events associated with tumor suppressor gene product-induced senescence or apoptotic cell death of tissue-resident stem/progenitor cells during chronological aging ENSG00000149311 ENSG00000136997 PMC6562892__F2 PPAR (peroxisome proliferator-activated receptor) signaling pathway enriched of differentially expressed genes (DEGs) in the jejunum of broiler chickens ENSG00000130304 ENSG00000157184 ENSG00000135218 ENSG00000150991 ENSG00000167114 ENSG00000100979 ENSG00000115361 ENSG00000124253 ENSG00000113790 PMC7554122__F3 TGFB2-Hepcidin feed-forward loop ENSG00000105697 PMC8124305__F3 S-Nitrosylation in Tumor Microenvironment ENSG00000019991 ENSG00000087245 ENSG00000115008 ENSG00000111537 ENSG00000117091 ENSG00000291971 ENSG00000100985 ENSG00000168610 ENSG00000026103 PMC3193469__F4 Simplified cartoons illustrating the components of the cullin–RING E3 ligases (CRLs) ENSG00000100387 ENSG00000134982 ENSG00000113558 ENSG00000115266 ENSG00000167986 ENSG00000117399 PMC4355029__F4 RNA toxicity leads to activation of NFKB pathway ENSG00000104856 ENSG00000110330 PMC7376907__F1 Macroautophagy and mitophagy ENSG00000123395 ENSG00000198382 ENSG00000123240 ENSG00000198793 ENSG00000057663 PMC5073094__F2 Stimuli for degranulation of mast cells and basophils and interplay/overlap with type II-IV reactions ENSG00000283887 ENSG00000078747 ENSG00000122121 ENSG00000275565 PMC7376907__F2 NLRP3 and AIM2 inflammasome pathways ENSG00000278718 ENSG00000162711 ENSG00000163568 PMC7404091__F1 This figure summarizes the regulatory core of ferroptosis, approximately divided into three axes ENSG00000161905 ENSG00000167468 ENSG00000111684 ENSG00000187855 ENSG00000057663 ENSG00000079999 PMC3193469__F6 Model of GA-induced DELLA protein degradation and the regulation of PIF protein function ENSG00000100387 ENSG00000113558 PMC3237253__F3 Adhesion of sickle red blood cells to the endothelium and cell activation ENSG00000135218 ENSG00000026508 ENSG00000162692 ENSG00000187244 PMC11576158__F2 Is choline kinase alpha a drug target for obesity? ENSG00000142611 ENSG00000096717 ENSG00000132170 PMC6930181__F2 Metabolic features of healthy and dysfunctional endothelial cells ENSG00000081181 ENSG00000169710 ENSG00000146701 ENSG00000082212 ENSG00000115419 PMC9149409__F7 Long Noncoding RNA MEG3-205/Let-7a/MyD88 Axis Promotes Renal Inflammation and Fibrosis in Diabetic Nephropathy ENSG00000172936 ENSG00000123908 PMC6155137__F8 GRP75 modulates oncogenic Dbl-driven endocytosis derailed via the CHIP-mediated ubiquitin degradation pathway ENSG00000070831 ENSG00000163914 PMC1698952__F4 Aspects of PRLR signaling as related to mammary gland function ENSG00000291971 ENSG00000169047 ENSG00000135605 ENSG00000113494 PMC6836431__F1 mTORC1 and its signaling networks ENSG00000101407 ENSG00000177169 ENSG00000128272 ENSG00000148400 ENSG00000074181 ENSG00000106070 ENSG00000198793 ENSG00000155792 ENSG00000167965 PMC10451996__F12 Mechanism by which fibroblast upregulation of VDR suppresses lung fibroblast proliferation and activation during pulmonary fibrosis ENSG00000168610 PMC5655592__F6 Genes affected concordantly within the ileum and meta-analysis data sets formed biofunctional clusters of overlapping pathways ENSG00000163599 PMC5655592__F3 The antigen presentation pathway was downregulated in the GF mice ENSG00000070831 ENSG00000232326 ENSG00000205220 ENSG00000256646 ENSG00000041357 ENSG00000163631 PMC5655592__F4 Intraset concordancy and transcriptome-proteome discordancy of gene products related to protein translation, OxP, and chaperone proteins ENSG00000131469 ENSG00000110700 ENSG00000168028 ENSG00000132109 ENSG00000105428 ENSG00000265681 ENSG00000198918 ENSG00000124614 ENSG00000105193 ENSG00000117118 ENSG00000156482 ENSG00000127022 ENSG00000162924 ENSG00000174444 ENSG00000104368 ENSG00000126803 ENSG00000112306 ENSG00000105821 PMC5715866__F6 Schematic showing the roles of EGFR ligands and NRG1 in the regulation of timing of ovulation and oocyte maturation ENSG00000065361 ENSG00000109321 ENSG00000124882 ENSG00000146648 PMC5779007__F7 HIF‐1A strongly associates with differentially expressed genes in rAAA ENSG00000167772 ENSG00000185215 ENSG00000105697 ENSG00000135245 ENSG00000150630 PMC8616463__F3 Global Reprogramming of Apoptosis-Related Genes during Brain Development ENSG00000149311 ENSG00000102871 ENSG00000162924 ENSG00000168040 ENSG00000127948 ENSG00000084774 PMC8643334__F1 Hepatitis B Virus e Antigen and Viral Persistence ENSG00000125538 PMC9018988__F1 Molecular Network of Colorectal Cancer and Current Therapeutic Options ENSG00000157764 ENSG00000134982 ENSG00000170430 PMC5039366__F5 Potential Function of Exogenous Vimentin on the Activation of Wnt Signaling Pathway in Cancer Cells ENSG00000134982 ENSG00000168036 PMC7106732__F2 Histone chaperone landscape of breast cancer metastasis ENSG00000145604 ENSG00000124102 ENSG00000181163 ENSG00000143401 ENSG00000123485 ENSG00000129514 ENSG00000124795 PMC3172097__F1 Autophagy pathway in plants ENSG00000152348 ENSG00000126775 ENSG00000145782 PMC7318302__F1 Correlation of Notch signaling pathway and ER in breast cancer endocrine resistance ENSG00000076706 ENSG00000146648 PMC8817240__F7 Sam68 contributes to intestinal inflammation in experimental and human colitis ENSG00000169245 ENSG00000173039 ENSG00000164400 ENSG00000121807 PMC7554194__F2 Other signals that regulate Schwann cell development ENSG00000134982 ENSG00000133067 ENSG00000170558 ENSG00000175591 ENSG00000089041 ENSG00000198670 ENSG00000169860 PMC7554194__F3 Schwann cells integrate signals from the extracellular matrix (ECM) including mechanical forces, laminins and collagens ENSG00000122877 ENSG00000091409 ENSG00000173402 ENSG00000087460 PMC3799862__F5 Role of TRAF6 in RANK Signal Transduction Pathway ENSG00000082512 ENSG00000198793 ENSG00000157625 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000131196 PMC6375727__F7 eIF2BE Constitutes a Pivotal Node between the Responses to Canonical Stress and Sema3ASema3A induces an initial (5 min) wave of local translation independent of the eIF2 pathway mediated by ERK-1/2 and mTOR ENSG00000198793 ENSG00000111361 ENSG00000075213 PMC4848607__F1 KEGG pathway analysis for the Toll like receptor (TLR) signaling pathway differentially expressed genes (DEGs) expressed in response to SAV-3 infection in TO-cells ENSG00000239732 ENSG00000144410 ENSG00000170458 ENSG00000117400 ENSG00000131323 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 ENSG00000143387 PMC9040670__F8 Amino Acid and Fatty Acid Metabolism Disorders Trigger Oxidative Stress and Inflammatory Response in Excessive Dietary Valine-Induced NAFLD of Laying Hens ENSG00000128272 ENSG00000144895 ENSG00000070669 ENSG00000026103 PMC3573143__F2 Regulation of autophagy in response to stress ENSG00000128272 ENSG00000144895 ENSG00000198793 ENSG00000145782 PMC4848607__F2 Summary of the Toll like receptors (TLR) and RIG-I like receptor (RLR) pathway genes based on upregulated genes shown in and excluding the downregulated genes shown in and ENSG00000276561 PMC6700252__F3 Intrinsic intracellular signaling cascades of BDNF-TrkB and TrkB-A2a receptors ENSG00000124102 PMC5729535__F1 Extrinsic and intrinsic apoptotic pathways ENSG00000120868 ENSG00000168040 PMC8427766__F3 COVID-19 Immunobiology: Lessons Learned, New Questions Arise ENSG00000213928 ENSG00000150455 ENSG00000108691 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000170458 ENSG00000136869 ENSG00000157625 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC7457511__F9 Network analysis of DCAF subfamily genes ENSG00000174989 ENSG00000130311 ENSG00000263324 ENSG00000176871 ENSG00000103091 ENSG00000164934 ENSG00000115827 ENSG00000145041 ENSG00000065717 ENSG00000126545 ENSG00000163257 ENSG00000122741 ENSG00000073536 ENSG00000162923 ENSG00000196981 ENSG00000203760 ENSG00000198889 ENSG00000101654 ENSG00000140543 ENSG00000198354 ENSG00000105447 ENSG00000121270 ENSG00000177352 ENSG00000197586 ENSG00000167196 ENSG00000166167 ENSG00000136485 ENSG00000198876 ENSG00000136045 ENSG00000116138 ENSG00000134940 ENSG00000165496 ENSG00000179914 ENSG00000139990 ENSG00000187147 ENSG00000140854 ENSG00000161654 ENSG00000183077 ENSG00000134574 ENSG00000143476 ENSG00000167986 ENSG00000139842 ENSG00000146247 ENSG00000185658 ENSG00000288453 ENSG00000113851 ENSG00000108840 ENSG00000092470 ENSG00000169375 ENSG00000110497 ENSG00000163114 ENSG00000074266 PMC8427766__F4 COVID-19 Immunobiology: Lessons Learned, New Questions Arise ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000115415 ENSG00000131323 PMC10453169__F5 Hedgehog Signaling Pathway in Head and Neck Squamous Cell Carcinoma ENSG00000164690 ENSG00000128602 PMC4305100__F3 Interaction of HBV and TLR2/4 ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC6275186__F2 Representative image of the participation of SARA in the TGFB signaling pathway ENSG00000102189 ENSG00000168938 PMC10453169__F2 Schematic model of the canonical HH signaling pathway ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC4645345__F9 Proposed mechanism for SCG2 expression in HSV- and reovirus-infected cells ENSG00000163914 ENSG00000171951 PMC9454399__F5 Qingfei Jiedu decoction inhibits PD-L1 expression in lung adenocarcinoma based on network pharmacology analysis, molecular docking and experimental verification ENSG00000164151 ENSG00000101751 ENSG00000213658 ENSG00000261857 ENSG00000156127 ENSG00000150455 ENSG00000119125 PMC7923165__F2 B-cell receptor signaling pathway is enriched in SYK targets in the DG75 Burkitt lymphoma cell line ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000145321 ENSG00000152689 ENSG00000010671 PMC7264416__F4 Protein–protein interaction (PPI) network and pathway involving the survival-associated features ENSG00000213658 ENSG00000170458 ENSG00000132646 ENSG00000163794 ENSG00000213614 ENSG00000150455 ENSG00000132849 ENSG00000164949 PMC7923165__F3 Actin cytoskeleton regulation pathway is enriched in SYK targets in the MCF7 and MDA231 breast cancer cell lines ENSG00000180210 ENSG00000134982 ENSG00000163914 ENSG00000089159 PMC8979960__F7 Involvement of Huanglian Jiedu Decoction on Microglia with Abnormal Sphingolipid Metabolism in Alzheimer’s Disease ENSG00000063176 ENSG00000198964 ENSG00000100596 ENSG00000143418 PMC2587278__F1 Oxidative and alkylation DNA damage is effectively repaired by the DNA BER pathway ENSG00000042832 ENSG00000108924 ENSG00000140398 PMC5650494__F3 Immune mediators in the brain and peripheral tissues in autism spectrum disorder PMC8418145__F2 Role and Regulatory Mechanism of Transcription Factor EB in Health and Diseases ENSG00000158828 ENSG00000112561 PMC5368188__F5 LIN28A/ZCCHC11 regulation of let-7 microRNA biogenesis, promoting cellular proliferation and modifying bioenergetics ENSG00000228716 ENSG00000112576 ENSG00000171105 ENSG00000164327 ENSG00000145386 ENSG00000118971 ENSG00000187772 ENSG00000167900 ENSG00000123472 ENSG00000100100 ENSG00000128050 ENSG00000131914 ENSG00000004455 ENSG00000134057 ENSG00000136997 ENSG00000073792 ENSG00000105810 ENSG00000159399 ENSG00000062485 PMC5368188__F6 Transcriptional networks that regulate LIN28B expression ENSG00000084093 ENSG00000136997 ENSG00000077463 ENSG00000187772 PMC8408558__AF1 LINC01189-miR-586-ZEB1 feedback loop regulates breast cancer progression through Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000155011 ENSG00000050165 ENSG00000168036 ENSG00000104332 ENSG00000196628 PMC9381797__F1 Insulin signaling pathway was found to be associated with cerebrovascular pathologies in AD including inflammation, BBB disruption, and AB accumulation ENSG00000184207 ENSG00000162692 PMC4830430__F4 Functional interplay between PPM1G and the transcription elongation machinery ENSG00000136807 ENSG00000174720 ENSG00000149311 ENSG00000146834 PMC11688061__F7 Jak-STAT signaling pathway and related target expression, such as STAT ENSG00000134086 ENSG00000213928 ENSG00000105397 ENSG00000100387 ENSG00000198793 ENSG00000072274 ENSG00000136869 ENSG00000131095 PMC7880745__F7 Anti-metastatic Effects of Cationic KT2 Peptide (a Lysine/Tryptophan-rich Peptide) on Human Melanoma A375.S2 Cells ENSG00000177606 PMC4868719__F7 Notch and Wnt/Beta-catenin signaling pathway play important roles in activating liver cancer stem cells ENSG00000154342 ENSG00000134982 ENSG00000114315 PMC7537138__F4 SARS‐CoV‐2 and the possible connection to ERs, ACE2, and RAGE: Focus on susceptibility factors ENSG00000291971 ENSG00000130234 ENSG00000132478 PMC6472151__F1 The effects of thyroid hormones on the activity and expression level of eNOS in vascular endothelial cells ENSG00000124102 PMC3251651__F4 Novel method of transcriptional response analysis to facilitate drug repositioning for cancer therapy ENSG00000228716 ENSG00000101945 ENSG00000132646 ENSG00000169375 PMC5897396__F7 The proposed PTN pro-migratory signaling pathway that leads to CDK5 activation in human endothelial cells ENSG00000105894 PMC7884184__F2 The Keap1-Nrf2 signalling pathway in antioxidative stress-related radio- and chemoresistance ENSG00000112561 ENSG00000079999 PMC7884184__F3 (1) The role of the PI3K-AKT signalling pathway in antioxidative stress related to radio- and chemoresistance PMC9702353__F8 Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NFKB/NLRP3 signaling pathway ENSG00000278718 ENSG00000162711 PMC3249608__F2 RA-dependent non-transcriptional involvement in neurite outgrowth ENSG00000002330 ENSG00000005882 ENSG00000198793 PMC5632457__F1 Predicted target genes of miRNA-34a in renal cell carcinoma pathway [KEGG hsa05211] ENSG00000019991 ENSG00000134086 ENSG00000005339 ENSG00000163235 ENSG00000177606 ENSG00000112715 ENSG00000100485 ENSG00000130669 ENSG00000179295 PMC3753703__F3 Alterations within the TP53 and RB1/E2F3 pathways in high-grade bladder cancer ENSG00000112242 ENSG00000139687 PMC8025646__F1 Signals and molecules of pathological phagocytosis between microglia and target cell ENSG00000153208 ENSG00000198053 PMC8301007__F8 Quercetin Alleviates the Accumulation of Superoxide in Sodium Iodate-Induced Retinal Autophagy by Regulating Mitochondrial Reactive Oxygen Species Homeostasis through Enhanced Deacetyl-SOD2 via the Nrf2-PGC-1Alpha-Sirt1 Pathway ENSG00000096717 PMC6511634__F8 Schematic illustration for the potential mechanisms of PC4 in AIPC progression ENSG00000168036 ENSG00000105810 PMC9280721__F1 MTOR Signaling in Cardiovascular Disease to Target Acute and Chronic Inflammation ENSG00000101407 ENSG00000198793 ENSG00000118515 ENSG00000155792 ENSG00000167965 PMC11529026__F2 Smad-dependent and Smad-independent TGFB signaling in EndoMT ENSG00000170558 PMC4495377__F5 The flow of glucose carbons in the presence of added fructose in adipocytes ENSG00000065911 ENSG00000100714 ENSG00000163738 ENSG00000112992 PMC5578007__F2 Notch signaling modulates endothelial cells’ (EC) fate associated with neointimal hyperplasia ENSG00000148400 PMC4147035__F1 NFKB: A Coordinator for Epigenetic Regulation by MLL ENSG00000078399 ENSG00000104885 ENSG00000173039 ENSG00000143995 PMC6469758__F7 TLR2/4 signaling pathway mediates sperm-induced inflammation in bovine endometrial epithelial cells in vitro ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC7753765__F3 Viruses join the circular RNA world ENSG00000213186 ENSG00000164342 PMC3408195__F9 A novel KRAS-initiated pathway leading to the activation of VMP1 in cancer cells ENSG00000106571 ENSG00000062716 PMC5392402__F1 The workflow of PAIRS ENSG00000148798 PMC3749885__F2 Pim kinase targets and their roles in inflammation and cancer ENSG00000002330 ENSG00000102034 PMC7016599__F2 Some of the signaling pathways regulated by integrin A6B4 in colorectal cancer cells ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC8392871__F5 Novel Polyethylene Glycol-Conjugated Triazole Derivative with High Thyrointegrin AvB3 Affinity in Acute Myeloid Leukemia Management ENSG00000291971 ENSG00000128342 ENSG00000166670 ENSG00000060762 PMC8698607__F6 Comparative Proteomic Analysis of tPVAT during Ang II Infusion ENSG00000198793 ENSG00000168610 PMC6639052__F2 Proposed role of NEDD4 in IGF-1R signaling ENSG00000069869 ENSG00000106070 ENSG00000169047 ENSG00000140443 PMC5558474__F3 Impact of glucocorticoid on neurogenesis ENSG00000118515 ENSG00000168036 ENSG00000128602 PMC8839902__F1 Macronutrients, Micronutrients and Flavonoid Polyphenols in the Prevention and Treatment of Osteoporosis ENSG00000178860 ENSG00000152266 ENSG00000170365 ENSG00000168036 PMC7929780__F7 Canonical Notch signaling with points of intervention of current therapies ENSG00000137845 ENSG00000182667 PMC2474948__F1 Integration of the TGFB1 apoptotic signal by the lipid oxidation end-product 4-hydroxynonenal ENSG00000105329 PMC8703169__F3 Mitophagy in Diabetic Kidney Disease ENSG00000145604 ENSG00000112561 ENSG00000142082 PMC8586418__F1 Recent Progress in Interferon Therapy for Myeloid Malignancies ENSG00000183735 ENSG00000213928 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000127191 ENSG00000276561 ENSG00000026103 PMC8703169__F1 Mitophagy in Diabetic Kidney Disease ENSG00000175193 ENSG00000127481 ENSG00000159459 ENSG00000165280 PMC2916219__F5 A model for regulation pathways responsible for RN and AM symbioses ENSG00000136997 ENSG00000125450 PMC11979243__F3 Exosomes from different mesenchymal stem cells mediate apoptosis in brain cells after cerebral ischemia-reperfusion injury ENSG00000124422 ENSG00000163568 ENSG00000150907 ENSG00000198793 ENSG00000096717 PMC12149175__F0 Dose-dependent immunotoxic mechanisms of celastrol via modulation of the PI3K-Akt signaling pathway ENSG00000198793 ENSG00000146648 PMC11988641__F1 MMP13 orchestrates dynamic remodelling of the extracellular matrix (ECM)’s physical properties ENSG00000100985 ENSG00000146648 PMC11520424__F3 STAT3 in HER2-positive breast cancer ENSG00000291971 ENSG00000138798 ENSG00000168610 PMC2901871__F7 Gemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesis ENSG00000142252 ENSG00000152147 ENSG00000046647 ENSG00000164902 ENSG00000092208 PMC8795506__F9 Mesenchymal Stem Cells Overexpressing ACE2 Favorably Ameliorate LPS-Induced Inflammatory Injury in Mammary Epithelial Cells ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC8988049__F7 Proteome-Level Investigation Into Plasmodiophora brassicae Resistance in Brassica napus Canola ENSG00000105722 ENSG00000136997 PMC11520424__F2 Main STAT3 signal transduction pathways in breast cancer ENSG00000187682 ENSG00000196090 ENSG00000112964 ENSG00000081237 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000137193 ENSG00000103522 ENSG00000168610 ENSG00000145623 ENSG00000122756 ENSG00000146648 ENSG00000158050 ENSG00000168685 ENSG00000130726 PMC10536292__F9 Theabrownin from Dark Tea Ameliorates Insulin Resistance via Attenuating Oxidative Stress and Modulating IRS-1/PI3K/Akt Pathway in HepG2 Cells ENSG00000130164 ENSG00000150907 ENSG00000113161 ENSG00000169710 ENSG00000169174 PMC10759256__F1 DMMIC derivatization-assisted liquid chromatography-mass spectrometry method for metabolite profiling of the glutathione anabolic pathway in esophageal cancer tissues and cells ENSG00000023909 PMC6624737__F1 Simplified demonstration of decarboxylation events with associated position-specific isotopomers used in this study ENSG00000173599 ENSG00000166278 PMC7546399__F9 Network diagram of the metabolic pathways regulated by XFZYD on d 3 and 21 ENSG00000151834 ENSG00000118520 PMC4832872__F3 Inflammation in gastric cancer: Interplay of the COX‐2/prostaglandin E2 and Toll‐like receptor/MyD88 pathways ENSG00000170458 ENSG00000026508 ENSG00000189403 ENSG00000172936 ENSG00000168610 PMC7082326__F1 Mitochondrial PTEN-succinate axis promotes P ENSG00000162711 ENSG00000125538 ENSG00000136869 ENSG00000091106 ENSG00000001626 PMC7333287__F9 PI3K-Akt signaling pathway influenced by XLGB ENSG00000002330 ENSG00000138798 ENSG00000136997 ENSG00000123374 ENSG00000171791 ENSG00000146648 PMC9667311__F2 Ultrahigh resolution MS1/MS2-based reconstruction of metabolic networks in mammalian cells reveals changes for selenite and arsenite action ENSG00000121067 PMC3868569__F10 TATN-1 Mutations Reveal a Novel Role for Tyrosine as a Metabolic Signal That Influences Developmental Decisions and Longevity in Caenorhabditis elegans PMC3804348__F1 Regulation of lipid metabolism in glioblastoma and the therapeutic drug targets ENSG00000130164 ENSG00000198793 ENSG00000026103 PMC6751266__F1 Overview of microRNA-27a biogenesis, highlighting key enzymes in miRNA biogenesis ENSG00000124571 ENSG00000128191 ENSG00000113360 PMC6751266__F2 Brief conclusion of miR-27a in regulating cell signal pathways Panel gray, miR-27a can regulate Ras/MAPK/ERK pathway to active key gene such as c-myc ENSG00000137834 ENSG00000138798 ENSG00000150907 ENSG00000168036 ENSG00000040199 ENSG00000109670 PMC6896744__F1 Schematic overview of the WNT signaling pathway ENSG00000281324 ENSG00000137673 ENSG00000162337 ENSG00000149968 ENSG00000156299 ENSG00000134982 ENSG00000168036 ENSG00000137845 PMC6466116__F5 Transcriptomic analysis of Fgf10+/− versus control P3 lungs in NOX suggests that reduced Fgf10 expression could lead to vascular defects ENSG00000070193 ENSG00000002330 ENSG00000169750 ENSG00000067900 ENSG00000159899 ENSG00000151617 ENSG00000087460 ENSG00000254550 PMC7533107__F1 TRPM2, linking oxidative stress and Ca2+ permeation to NLRP3 inflammasome activation ENSG00000278718 ENSG00000162711 ENSG00000125538 ENSG00000169429 ENSG00000136869 PMC6109817__F2 Cross-talk between oestrogen (ER) and epidermal growth factor receptor (EGFR)/insulin-like growth factor 1 receptor (IGF-1R) signalling pathway and cyclin-dependent kinase (CDK)4/6 function ENSG00000135446 ENSG00000198793 ENSG00000140443 PMC5490640__F4 Ubiquitin enzymes in the regulation of T cell-mediated autoimmunity ENSG00000145604 ENSG00000103266 ENSG00000291603 ENSG00000160224 ENSG00000078747 ENSG00000173039 ENSG00000083799 ENSG00000049768 PMC5490640__F5 Ubiquitination in B cell activation ENSG00000264522 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC6975291__F11 The proposed pathway for suppression of glutamate release by postsynaptic metabotropic NMDAR signaling to Panx1 ENSG00000117480 ENSG00000291971 ENSG00000110218 ENSG00000196689 PMC5490640__F6 Ubiquitin chains and ubiquitin enzymes in the TNF-induced NFKB and apoptosis pathways ENSG00000137275 ENSG00000102871 ENSG00000173039 ENSG00000083799 ENSG00000168040 ENSG00000154124 ENSG00000127191 PMC5490640__F7 TRIMs in the regulation of the immune response ENSG00000121236 ENSG00000169871 ENSG00000121060 ENSG00000141569 PMC5490640__F3 Ubiquitin enzymes in the TCR signaling pathway ENSG00000184979 ENSG00000135655 ENSG00000264522 ENSG00000291603 ENSG00000197530 ENSG00000078747 ENSG00000173599 ENSG00000173039 ENSG00000083799 ENSG00000124181 PMC9581404__F3 Adherens junction proteins on the move—From the membrane to the nucleus in intestinal diseases ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC2895421__F2 Convergent signaling pathways where inflammation and metabolic signaling intersect along the CHIEF pathway ENSG00000120833 ENSG00000104365 ENSG00000198793 ENSG00000113520 ENSG00000121879 PMC9581404__F2 Adherens junction proteins on the move—From the membrane to the nucleus in intestinal diseases ENSG00000134982 ENSG00000168036 PMC5458740__F1 ECM–cell communication is dictated by focal-adhesion players ENSG00000291971 ENSG00000198793 ENSG00000168036 PMC5604037__F6 Schematic overview of MYC-mediated metabolic pathways ENSG00000228716 ENSG00000128050 ENSG00000065911 ENSG00000196549 ENSG00000153574 ENSG00000102967 ENSG00000084774 ENSG00000254550 ENSG00000116984 ENSG00000152556 PMC5016689__F7 Proposed model for the impact of CCL2 on HDL internalization and cholesterol efflux and regulatory mechanisms in HCAECs ENSG00000108691 ENSG00000183625 ENSG00000121807 PMC10376673__F1 Breaking Bad: Inflammasome Activation by Respiratory Viruses ENSG00000278718 ENSG00000162711 ENSG00000164430 PMC2668236__F2 Major pathway and inflammatory mediators of sepsis and its related conditions ENSG00000170458 ENSG00000162692 PMC10489316__F9 Details of KEGG pathways of Ras, PI3K-Akt, and MAPK signaling pathway ENSG00000002330 ENSG00000213658 ENSG00000070831 ENSG00000163914 ENSG00000172005 ENSG00000108061 PMC5009769__F1 Wnt pathway regulation of intestinal stem cells ENSG00000156076 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000026508 ENSG00000168036 PMC7509716__F1 Proposed mechanism for enhancing antigen‐specific immune response by the CS‐IONzyme‐based influenza vaccine ENSG00000177606 PMC5009769__F3 Wnt pathway regulation of intestinal stem cells ENSG00000281324 ENSG00000162337 ENSG00000133067 ENSG00000183579 ENSG00000108375 PMC6232757__F1 Representative scheme of the presence of O-GlcNAcylation on glucose metabolism in skeletal muscle ENSG00000147162 ENSG00000198408 ENSG00000169047 PMC5335506__F2A Interactome Analysis Reveals a Novel Role for RAD6 in the Regulation of Proteasome Activity and Localization in Response to DNA Damage ENSG00000140319 ENSG00000047410 ENSG00000105835 ENSG00000196839 ENSG00000160710 ENSG00000046604 ENSG00000079999 ENSG00000143815 ENSG00000291836 ENSG00000184110 ENSG00000119203 ENSG00000198087 ENSG00000125818 ENSG00000117528 ENSG00000102119 ENSG00000163554 ENSG00000074266 ENSG00000175390 ENSG00000108344 ENSG00000196465 PMC7011400__F5 Proposed model for the effects of BSZYD on HEMEC angiogenesis through the VEGFR-2-mediated regulation of the MAPK signaling pathway ENSG00000132646 ENSG00000100985 PMC10910758__F7 Therapeutics of endochondral ossification and FOP targeting NFKB signalling ENSG00000178860 ENSG00000170365 ENSG00000125398 ENSG00000120693 ENSG00000173039 ENSG00000189403 ENSG00000136869 ENSG00000096717 ENSG00000125968 PMC10878139__F5 TGFB signaling pathway mediates the effect of the GR signaling pathway in the TM PMC10878139__F3 Cross-talk between glucocorticoid receptor and YAP/TAZ signaling pathways ENSG00000150457 ENSG00000131023 PMC10878139__F4 Cross-talk between glucocorticoid receptor and Wnt signaling pathways ENSG00000169071 ENSG00000134982 ENSG00000168036 ENSG00000104332 ENSG00000168646 PMC11201249__F2 Schematic presentation of mTOR modulation pathways ENSG00000100150 ENSG00000114388 ENSG00000198793 PMC3974856__F2 Tolerogenic plasmacytoid DC ENSG00000239732 ENSG00000162692 ENSG00000121966 ENSG00000112486 PMC10910758__F1 Simplified diagram of the canonical pathway and alternative pathway of the NFKB signalling pathway (Created with BioRender ENSG00000104856 ENSG00000136869 PMC2533023__F5 Response of A549 cells exposed to crocidolite ENSG00000087510 ENSG00000120833 ENSG00000153094 ENSG00000148926 ENSG00000120889 ENSG00000099860 ENSG00000162772 ENSG00000136826 ENSG00000106546 ENSG00000011422 ENSG00000136997 ENSG00000163734 ENSG00000006327 ENSG00000135116 ENSG00000050405 ENSG00000251493 ENSG00000130513 ENSG00000023445 ENSG00000081041 ENSG00000087074 ENSG00000134363 ENSG00000116741 ENSG00000116717 ENSG00000150457 ENSG00000073756 ENSG00000153487 ENSG00000118503 ENSG00000134070 ENSG00000128564 ENSG00000198355 ENSG00000143669 ENSG00000127616 ENSG00000164949 ENSG00000173334 ENSG00000150630 PMC10910758__F4 NFKB signalling during chondrogenesis in endochondral ossification ENSG00000178860 ENSG00000125398 PMC10910758__F6 Scheme of FOP pathogenesis and the involvement of NFKB signalling ENSG00000178860 ENSG00000170365 ENSG00000136960 ENSG00000125398 ENSG00000198793 ENSG00000120693 ENSG00000189403 ENSG00000136869 ENSG00000198670 ENSG00000125968 PMC8454549__F3 Regulatory Role of Retinoic Acid in Male Pregnancy of the Seahorse ENSG00000111057 ENSG00000143320 ENSG00000167910 ENSG00000164093 ENSG00000164690 ENSG00000134871 PMC7816290__F7 PPI network and Path-Act-Network analyses ENSG00000151725 ENSG00000138778 ENSG00000090402 ENSG00000108055 ENSG00000109805 ENSG00000143228 ENSG00000138160 ENSG00000112742 PMC6540047__F6 BRO priming of NFkB target gene expression in the absence of virus ENSG00000171855 ENSG00000105967 ENSG00000081041 ENSG00000105835 ENSG00000100906 ENSG00000232326 ENSG00000125347 ENSG00000276561 ENSG00000277943 ENSG00000007171 ENSG00000169245 ENSG00000108691 ENSG00000134321 ENSG00000224320 ENSG00000144802 ENSG00000118503 ENSG00000138755 ENSG00000288512 ENSG00000164136 ENSG00000164400 ENSG00000128342 ENSG00000162692 PMC6540047__F4 BRO modulation of RV-induced NFkB target gene expression ENSG00000105967 ENSG00000144802 ENSG00000105835 ENSG00000100906 PMC6540047__F5 BRO priming of interferon response pathway in the absence of virus ENSG00000127445 ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000250361 ENSG00000187608 ENSG00000184995 ENSG00000137275 ENSG00000131323 ENSG00000168040 PMC7583882__F1 Schematic summary of Sphingosine 1 Phosphate (S1P)/S1PR (G-protein-coupled receptor) agonist and antagonist signalling ENSG00000063176 ENSG00000163914 PMC8615162__F2 Coenzyme Q at the Hinge of Health and Metabolic Diseases ENSG00000130164 ENSG00000157764 ENSG00000171503 ENSG00000175193 ENSG00000165650 ENSG00000160746 ENSG00000116688 ENSG00000113161 ENSG00000102967 ENSG00000171109 PMC5958474__F8 Oxygen sensors, VEGF pathway regulators and stem cell master regulators regulate DNA damage response gene expression in human tissues ENSG00000157404 ENSG00000128052 ENSG00000136997 ENSG00000204531 ENSG00000174059 ENSG00000037280 ENSG00000112715 ENSG00000136826 ENSG00000150630 PMC2810142__F9 Network diagram of Sp1-interacting proteins ENSG00000145604 ENSG00000135446 ENSG00000051180 ENSG00000185591 ENSG00000168610 ENSG00000139687 ENSG00000139618 PMC8850363__F1 Immune and Metabolic Alterations in Liver Fibrosis: A Disruption of Oxygen Homeostasis? ENSG00000107562 ENSG00000172046 PMC7591658__F6 BAG3 and BAG6 differentially affect the dynamics of stress granules by targeting distinct subsets of defective polypeptides released from ribosomes ENSG00000204463 ENSG00000165280 ENSG00000152137 ENSG00000151929 PMC5953448__F2 Breast cancer related pathways ENSG00000125826 ENSG00000285152 PMC4778564__F3 Hepatitis C Virus and Autophagy ENSG00000237693 ENSG00000145782 ENSG00000057663 PMC4778564__F4 Hepatitis C Virus and Autophagy ENSG00000088888 ENSG00000145782 ENSG00000057663 PMC8721920__F1 Interferon Control of Human Coronavirus Infection and Viral Evasion: Mechanistic Insights and Implications for Antiviral Drug and Vaccine Development ENSG00000213928 ENSG00000089127 ENSG00000278032 ENSG00000185745 ENSG00000276561 ENSG00000142166 ENSG00000184979 ENSG00000019582 ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000138135 ENSG00000105397 ENSG00000115415 ENSG00000172936 PMC9485831__F4 Biochemical and physiological insights into TRH receptor-mediated signaling ENSG00000157764 ENSG00000291971 ENSG00000168036 ENSG00000170893 PMC6020372__F2 Molecular mechanism model for lncRNAs involved in the tumorigenesis of human TNBC ENSG00000175793 ENSG00000117139 PMC9576167__F1 Platelets and tyrosine kinase inhibitors: clinical features, mechanisms of action, and effects on physiology ENSG00000213658 ENSG00000010810 ENSG00000197943 ENSG00000135605 ENSG00000010671 PMC5362544__F1 The association between copper transporters and the prognosis of cancer patients undergoing chemotherapy: a meta-analysis of literatures and datasets ENSG00000123191 ENSG00000177556 PMC3552512__F3 Oncogenic signals regulate each stage of translation ENSG00000101751 ENSG00000198793 ENSG00000136997 ENSG00000167658 ENSG00000164327 PMC11077368__F11 Schematic diagram explains the mechanism underlying by which SP protects against colitis ENSG00000169245 ENSG00000164430 ENSG00000151012 ENSG00000167468 PMC6265312__F1 Triggering receptor expressed on myeloid cells-2 (TREM2) in microglial survival and metabolism ENSG00000278718 ENSG00000125538 ENSG00000198793 ENSG00000173599 ENSG00000168036 ENSG00000137845 PMC8775565__F6 Physiological implications and importance of both simple-type and composite-type GSKIP in Wnt signaling ENSG00000168036 ENSG00000100744 PMC3389182__F1 Transcriptome analysis of HeLa cells response to Brucella melitensis infection: A molecular approach to understand the role of the mucosal epithelium in the onset of the Brucella pathogenesis ENSG00000172680 ENSG00000157764 ENSG00000101109 ENSG00000130758 ENSG00000269335 ENSG00000065559 ENSG00000116717 ENSG00000007047 ENSG00000213341 ENSG00000169032 ENSG00000162302 ENSG00000139625 ENSG00000100485 ENSG00000164305 ENSG00000127472 ENSG00000011566 ENSG00000177606 ENSG00000136997 ENSG00000130222 ENSG00000146648 PMC5206486__F1 Domain structure of retinoic acid-inducible gene-I (RIG-I) ENSG00000088888 ENSG00000105397 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000142166 PMC8497755__F1 Metabolic Modifications, Inflammation, and Cancer Immunotherapy ENSG00000138798 ENSG00000168036 ENSG00000163812 ENSG00000146648 ENSG00000179913 PMC8497755__F2 Metabolic Modifications, Inflammation, and Cancer Immunotherapy ENSG00000167207 ENSG00000172936 ENSG00000136869 ENSG00000168610 ENSG00000188818 ENSG00000023041 PMC8557192__F1 New biological triangle in cancer: intestinal microbiota, immune checkpoint inhibitors and antibiotics ENSG00000291603 PMC3856107__F3 Roles and signaling pathways of let-7 in hypoxia- and neural stem/progenitor cells (NSPCs)-induced angiogenesis ENSG00000092847 PMC5883109__F9 EH regulates PGN-induced inflammatory response in DCs ENSG00000134070 ENSG00000172936 ENSG00000150455 ENSG00000175104 PMC7486640__F5 One of the possible mechanisms of MFSD to alleviate the damage of high glucose to podocytes ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000196628 PMC3836362__F6 Interaction between dietary protein and mechanical loading on skeletal muscle cell ENSG00000198793 ENSG00000167658 PMC7912811__F1 Gonadotropin releasing hormone (GnRH) receptor signal transduction in endometrial cancer (EC) ENSG00000291971 ENSG00000130522 ENSG00000138798 ENSG00000146648 PMC11521822__F6 The angiogenic signaling pathway in lean vs ENSG00000122691 ENSG00000159346 ENSG00000285070 PMC5571156__F7 Mechanism of QE action PMC7912811__F2 Signal transduction of the putative truncated GnRH-II receptor in endometrial cancer (EC) ENSG00000130522 ENSG00000138798 ENSG00000146648 PMC7576257__F1 TRAIL signalling pathway ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC7054750__F1 Active integrin internalization and trafficking pathways ENSG00000185236 ENSG00000080371 ENSG00000096088 ENSG00000126458 PMC4383231__F1 Intracellular fatty acid metabolism ENSG00000135218 ENSG00000158669 ENSG00000198670 ENSG00000186281 PMC3097115__F5 PRP-17 and the pre-mRNA splicing pathway are preferentially required for the proliferation versus meiotic development decision and germline sex determination in Caenorhabditis elegans ENSG00000111605 ENSG00000151657 ENSG00000086589 ENSG00000105298 ENSG00000179950 ENSG00000063244 ENSG00000125870 ENSG00000102241 ENSG00000125352 ENSG00000131876 ENSG00000115524 ENSG00000099995 ENSG00000168066 ENSG00000106245 ENSG00000117614 ENSG00000175467 ENSG00000134597 ENSG00000130332 ENSG00000113593 ENSG00000100109 ENSG00000205937 ENSG00000146007 PMC4037811__F1 An Inside View: VEGF Receptor Trafficking and Signaling ENSG00000291971 PMC8220148__F7 Using Network Pharmacology and Molecular Docking to Explore the Mechanism of Shan Ci Gu (Cremastra appendiculata) Against Non-Small Cell Lung Cancer ENSG00000105722 ENSG00000100290 ENSG00000002330 ENSG00000135446 ENSG00000177606 PMC8220148__F5 Using Network Pharmacology and Molecular Docking to Explore the Mechanism of Shan Ci Gu (Cremastra appendiculata) Against Non-Small Cell Lung Cancer ENSG00000163464 ENSG00000114200 ENSG00000157404 ENSG00000105329 ENSG00000291971 ENSG00000198793 ENSG00000087085 ENSG00000113161 ENSG00000087586 ENSG00000148344 ENSG00000169032 ENSG00000121879 ENSG00000196396 ENSG00000010671 ENSG00000069667 ENSG00000122025 ENSG00000169291 ENSG00000082175 ENSG00000128052 ENSG00000077782 ENSG00000101213 ENSG00000105146 ENSG00000167434 ENSG00000168748 ENSG00000087245 ENSG00000125384 ENSG00000086991 ENSG00000105639 ENSG00000138160 ENSG00000007171 ENSG00000107854 ENSG00000100985 ENSG00000074410 ENSG00000146648 ENSG00000198911 ENSG00000173273 PMC3737722__F7 Model of cell-surface regulation of HH signaling ENSG00000064309 ENSG00000180447 ENSG00000117425 ENSG00000144857 ENSG00000128602 PMC3718318__F16 ROS in endoplasmic reticulum (ER) stress-induced cell death ENSG00000135218 ENSG00000198670 ENSG00000026103 PMC4179633__F7 Lcn2 role as a negative regulator in NFKB-STAT3 loop activation in macrophages ENSG00000148346 ENSG00000136869 ENSG00000168610 PMC7210384__F1 MGP Promotes Colon Cancer Proliferation by Activating the NFKB Pathway through Upregulation of the Calcium Signaling Pathway ENSG00000111341 ENSG00000112715 ENSG00000131196 PMC3228218__F1 HCG/MET signaling pathway ENSG00000019991 ENSG00000002330 ENSG00000070831 ENSG00000105810 PMC8297977__F6 Transcription Factors and Methylation Drive Prognostic miRNA Dysregulation in Hepatocellular Carcinoma ENSG00000143390 ENSG00000002330 ENSG00000164128 ENSG00000291971 ENSG00000157227 ENSG00000150907 ENSG00000118515 ENSG00000075239 ENSG00000121966 PMC9686558__F3 Ameliorative Effect of Tocotrienols on Perimenopausal-Associated Osteoporosis—A Review ENSG00000100387 ENSG00000079999 PMC7814560__F6 Possible mechanism of Sfrp1-attenuated AMI injury in aged mice ENSG00000107404 ENSG00000168036 ENSG00000104332 PMC10950953__F4 Immune cells interacted with jaw stem cells by signaling pathways ENSG00000178860 ENSG00000134982 ENSG00000164483 ENSG00000168036 ENSG00000128602 ENSG00000103335 PMC10950953__F5 Cellular interaction of immune cells and stem cells in the jaw ENSG00000178860 ENSG00000108691 PMC6258005__F3 Mitochondrial Fatty Acid Synthesis is the puppet master of mitochondrial biogenesis ENSG00000182511 ENSG00000147684 ENSG00000184983 ENSG00000164898 PMC5844827__F1 Respiratory viral infections and atopic development: From possible mechanisms to advances in treatment ENSG00000151882 ENSG00000107485 ENSG00000291905 PMC9650488__F6 Tripterygium wilfordii Hook.F.- Trichosanthes kirilowii Maxim decoction in treatment of diabetic kidney disease based on network pharmacology and molecular docking ENSG00000186063 ENSG00000177606 ENSG00000173039 ENSG00000127948 PMC3772117__F2 Regulation of proliferation, cell competition, and cellular growth by the Drosophila JAK-STAT pathway ENSG00000198901 PMC5397988__F2 Targeting Mitochondria and Reactive Oxygen Species-Driven Pathogenesis in Diabetic Nephropathy ENSG00000026103 PMC6309266__F3 Long (lncRNA) and short (miRNA) of it: TGFBeta-mediated Control of RNA-binding Proteins and non-coding RNAs ENSG00000105329 ENSG00000095002 PMC10530375__F3 Anti-Inflammatory Effects of Peripheral Dopamine ENSG00000154342 ENSG00000168036 PMC8318647__F1 Therapeutic mechanism of traditional Chinese medicine monomers on neurological recovery after spinal cord injury ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11813745__F1 Figure-Schematic illustration depicting the role of Phosphodiesterases in Endocrine system and associated diseases ENSG00000169245 ENSG00000253506 ENSG00000130234 ENSG00000173786 ENSG00000169429 PMC3020905__F6 Molecular Basis for Vulnerability to Mitochondrial and Oxidative Stress in a Neuroendocrine CRI-G1 Cell Line ENSG00000128272 PMC3149315__F1 Biosynthetic pathway of GSL and the CIRES procedure ENSG00000069482 ENSG00000176597 ENSG00000182272 ENSG00000115525 PMC7523373__F1 Structure of Bruton’s tyrosine kinase (BTK) and associated cross-linking signaling pathways ENSG00000095585 ENSG00000186716 ENSG00000010671 PMC6092430__F1 The mismatch repair pathway ENSG00000113318 ENSG00000132646 ENSG00000095002 ENSG00000122512 PMC9027630__F2 Osteopontin in Microglia Biology: Current Concepts and Future Perspectives ENSG00000070831 ENSG00000026508 PMC7461113__F1 Notch signaling pathway ENSG00000140564 ENSG00000198793 ENSG00000168036 PMC4973429__F2 Involvement of AKR1B1 in pathophysiology ENSG00000085662 PMC10854592__F2 STAT3 signaling pathway: STAT3 activation is initiated by upstream activity including ligand binding by (a) cytokines (IL-6 and non-IL-6 family members), (b) growth factors (EGF, FGF, etc ENSG00000122691 ENSG00000291971 ENSG00000168610 ENSG00000146648 PMC7821787__F1 MTOR signaling pathway and Rapalog therapeutic mechanisms ENSG00000198793 ENSG00000155792 ENSG00000164327 PMC3875765__F7 Chemoresistance to gemcitabine in hepatoma cells induces epithelial-mesenchymal transition and involves activation of PDGF-D pathway ENSG00000170962 PMC5722815__F6 BMP2 or BMP6 signaling enhances adipocyte function ENSG00000170365 ENSG00000137834 ENSG00000169710 ENSG00000283060 ENSG00000125968 ENSG00000132170 ENSG00000172201 PMC9451491__F4 Yuan-Zhi decoction in the treatment of Alzheimer’s disease: An integrated approach based on chemical profiling, network pharmacology, molecular docking and experimental evaluation ENSG00000150782 ENSG00000142192 ENSG00000196549 ENSG00000165280 ENSG00000113520 ENSG00000177301 ENSG00000112715 ENSG00000005381 ENSG00000109738 ENSG00000285456 PMC7425726__F9 Proposed regulatory pathway for FGF2 mediated mesenchymal transition in human corneal endothelial cells ENSG00000185591 PMC3312242__F1 Regulation of cancer stem cells by inflammatory cytokine networks ENSG00000163464 ENSG00000173039 ENSG00000083799 ENSG00000168610 PMC7457372__F6 Signaling pathway by which C2S NPs promote osteogenesis through an autophagy effect ENSG00000177169 ENSG00000198793 ENSG00000144848 ENSG00000284099 ENSG00000168036 PMC10902128__F4 TGFB signaling pathway ENSG00000102871 ENSG00000134982 ENSG00000186716 ENSG00000168040 ENSG00000127191 PMC7583994__F1 Rearranged in transfection (RET) receptor structure and its intracellular signaling pathway ENSG00000124102 ENSG00000187871 ENSG00000291971 ENSG00000106070 ENSG00000169047 ENSG00000168610 ENSG00000130513 PMC4716672__F3 Therapeutic Interventions to Disrupt the Protein Synthetic Machinery in Melanoma ENSG00000101751 ENSG00000198793 PMC4115620__F6 Pathway analysis for H3K9me3 enriched genes in baboon SVZ cells ENSG00000138795 ENSG00000070831 ENSG00000198793 ENSG00000164327 ENSG00000112715 ENSG00000148484 ENSG00000166135 ENSG00000149311 ENSG00000196531 ENSG00000134086 ENSG00000163914 ENSG00000071051 ENSG00000116030 ENSG00000100985 PMC12076972__F5 KEGG enrichment results related to the potential targets of Gyp LI ENSG00000180210 ENSG00000157404 ENSG00000291971 ENSG00000173083 ENSG00000123374 ENSG00000112715 ENSG00000146648 PMC11944911__F6 D-LA biosynthetic pathway in engineered S ENSG00000060762 PMC3547636__F2 G Protein-coupled Receptor FPR1 as a Pharmacologic Target in Inflammation and Human Glioblastoma ENSG00000291971 ENSG00000169429 ENSG00000168610 ENSG00000146648 ENSG00000171051 PMC5067255__F7 Proposed model for the profibrotic regulation of GLUT1 expression by TGFB PMC7564075__F4 Signaling mechanisms of CD271 ENSG00000040608 ENSG00000185652 ENSG00000106683 ENSG00000157764 ENSG00000177606 ENSG00000067900 ENSG00000134243 ENSG00000175104 ENSG00000092820 ENSG00000225950 PMC4147769__F2 Possible mechanisms of autophagy in mammalian cells ENSG00000124102 ENSG00000152348 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC8058227__F2 Ecdysone production and systemic release in response to dietary nutrient availability PMC4263456__F8 Myosin II accumulation and contractility are governed by a mechanosensitive control system ENSG00000140575 PMC8392544__F4 Applying Bioinformatic Platforms, In Vitro, and In Vivo Functional Assays in the Characterization of Genetic Variants in the GH/IGF Pathway Affecting Growth and Development ENSG00000112964 ENSG00000115415 ENSG00000168610 ENSG00000140443 PMC3774790__F8 Lmx1a Encodes a Rostral Set of Mesodiencephalic Dopaminergic Neurons Marked by the Wnt/B-Catenin Signaling Activator R-spondin 2 ENSG00000107859 ENSG00000282830 ENSG00000152192 ENSG00000162761 ENSG00000168036 ENSG00000125084 PMC9276970__F9 Extracellular Nucleosomes Accelerate Microglial Inflammation via C-Type Lectin Receptor 2D and Toll-Like Receptor 9 in mPFC of Mice With Chronic Stress ENSG00000162711 ENSG00000239732 ENSG00000125538 ENSG00000172936 PMC5488012__F1 Role of ROS in VEGF-mediated angiogenesis ENSG00000291971 ENSG00000086991 ENSG00000168610 PMC3298530__F7 Tentative scheme for luteolin regulation of the IGF-IR signaling pathway in HT-29 human colon cancer cells ENSG00000134057 ENSG00000169047 PMC3260001__F1 Abrogation of PIK3CA or PIK3R1 reduces proliferation, migration, and invasion in glioblastoma multiforme cells ENSG00000070831 ENSG00000178772 ENSG00000291971 ENSG00000198793 ENSG00000163914 ENSG00000067900 ENSG00000064012 PMC9681871__F2 SMAD-(in)dependent bone morphogenetic protein (BMP) signalling pathway (oversimplification) ENSG00000198742 PMC4253420__F7 Prolactin induces up-regulation of its cognate receptor in breast cancer cells via transcriptional activation of its generic promoter by cross-talk between ERA and STAT5 ENSG00000185591 ENSG00000113494 PMC4147769__F1 Simplified outline showing key proteins within the extrinsic and intrinsic apoptotic pathways in response to extra- and intracellular stress ENSG00000132906 ENSG00000168040 ENSG00000064012 ENSG00000164305 PMC8302405__F6 Network Pharmacology/Metabolomics-Based Validation of AMPK and PI3K/AKT Signaling Pathway as a Central Role of Shengqi Fuzheng Injection Regulation of Mitochondrial Dysfunction in Cancer-Related Fatigue ENSG00000133116 ENSG00000183691 ENSG00000172005 ENSG00000185591 ENSG00000026103 PMC4223072__F11 Epithelial AvB3-Integrin Boosts the MYD88-Dependent TLR2 Signaling in Response to Viral and Bacterial Components ENSG00000187796 ENSG00000291971 ENSG00000172936 ENSG00000184216 PMC1436036__F12 Core signaling pathway downstream from V2R occupation in IMCD ENSG00000167580 ENSG00000188191 ENSG00000141480 ENSG00000174233 ENSG00000125388 ENSG00000205268 ENSG00000154678 ENSG00000196218 ENSG00000079950 ENSG00000126895 ENSG00000087460 PMC3623872__F5 Nutrigenomics in Arma chinensis: Transcriptome Analysis of Arma chinensis Fed on Artificial Diet and Chinese Oak Silk Moth Antheraea pernyi Pupae ENSG00000157764 ENSG00000198793 ENSG00000198517 ENSG00000105656 ENSG00000164327 ENSG00000026103 PMC8914285__F3 New Insights of CCR7 Signaling in Dendritic Cell Migration and Inflammatory Diseases ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000126353 ENSG00000175104 ENSG00000184216 ENSG00000141968 PMC6694749__F5 PIKKs-related signaling pathway in the aging brain ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000291953 ENSG00000138385 ENSG00000106459 PMC155294__F4 Representation of the cell cycle control pathway within TIGR Orthologous Gene Alignment (TOGA) ENSG00000149311 ENSG00000112242 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000171791 ENSG00000282899 PMC7573473__F4 BCL-2 family members and their role in the apoptotic pathway ENSG00000002330 PMC7767993__F4 Key connectors of (A) T1D-bacterial infection in Wnt signaling pathway and (B) T2D-obesity in appendage morphogenesis ENSG00000100519 ENSG00000197746 ENSG00000196591 ENSG00000137699 ENSG00000165280 ENSG00000168036 ENSG00000196628 ENSG00000130706 ENSG00000150991 ENSG00000113558 ENSG00000136997 ENSG00000189403 ENSG00000215301 ENSG00000138795 ENSG00000142192 ENSG00000170027 ENSG00000103035 ENSG00000112335 ENSG00000109320 ENSG00000143013 ENSG00000161203 ENSG00000060237 ENSG00000173039 ENSG00000143933 ENSG00000108518 ENSG00000175166 ENSG00000177606 ENSG00000159352 ENSG00000129152 ENSG00000127824 ENSG00000137575 ENSG00000108344 ENSG00000108671 ENSG00000146648 ENSG00000173692 ENSG00000163636 ENSG00000041357 ENSG00000141367 ENSG00000155363 PMC11945976__F4 Where Biology Meets Engineering: Scaling Up Microbial Nutraceuticals to Bridge Nutrition, Therapeutics, and Global Impact ENSG00000197713 ENSG00000047597 ENSG00000158125 PMC6321037__F2 S100A10 plays a key role in regulating pro-tumorigenic processes including proliferation, adhesion, motility, invasion, metastasis, and therapy resistance ENSG00000182718 ENSG00000197747 ENSG00000122194 PMC4858120__F5 EGFR, HER‐2 and ER with downstream the RAS/RAF/MAPK and PI3K/AKT pathway ENSG00000157764 ENSG00000198793 ENSG00000146648 PMC9221026__F1 Translational Regulation in mTOR Pathway ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC9654823__F6 Equus Beta-Defensin-1 Regulates Innate IMMUNE Response in S. aureus-Infected Mouse Monocyte Macrophage ENSG00000108691 ENSG00000125538 PMC9221026__F2 Translational Regulation in mTOR Pathway ENSG00000155506 ENSG00000284161 ENSG00000167658 PMC10550586__F4 Representation of the KEGG TNF Signaling Pathway, showing up-regulated (red boxes) and down-regulated (green boxes) genes ENSG00000156735 ENSG00000110330 ENSG00000167207 ENSG00000165197 ENSG00000163739 ENSG00000124875 ENSG00000172216 ENSG00000157227 ENSG00000149968 ENSG00000078747 ENSG00000125538 ENSG00000056558 ENSG00000164400 ENSG00000157625 ENSG00000168404 ENSG00000026103 ENSG00000100906 ENSG00000109320 ENSG00000007908 ENSG00000213341 ENSG00000168040 ENSG00000127191 ENSG00000073756 ENSG00000226275 ENSG00000128272 ENSG00000177606 ENSG00000184371 ENSG00000131323 ENSG00000100985 ENSG00000285379 PMC4835942__F1 Ca2+-mediated regulation of autophagy in the heart ENSG00000177169 ENSG00000198793 ENSG00000112561 ENSG00000036828 ENSG00000057663 PMC9692129__F7 Spatiotemporal characteristics of P-selectin-induced B2 integrin activation of human neutrophils under flow ENSG00000197943 ENSG00000010671 PMC7883293__F8 ESM1 drives PCa metastasis by coordinating with the Wnt/B‐catenin pathway ENSG00000281324 ENSG00000164283 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC9143202__F9 Notch3-Mediated mTOR Signaling Pathway Is Involved in High Glucose-Induced Autophagy in Bovine Kidney Epithelial Cells ENSG00000074181 ENSG00000144848 PMC8647113__F9 Study of Baicalin toward COVID-19 Treatment: In silico Target Analysis and in vitro Inhibitory Effects on SARS-CoV-2 Proteases ENSG00000105664 ENSG00000169291 ENSG00000122218 ENSG00000111837 PMC8987494__F3 PI3K/Akt/mTOR Pathway and Its Role in Cancer Therapeutics: Are We Making Headway? ENSG00000198793 PMC11902984__F1 Pro-apoptotic TRAIL signaling pathway ENSG00000120868 ENSG00000168040 PMC11172074__F1 Effect of miR-21 on the PTEN/AKT Signaling Pathway ENSG00000291971 ENSG00000146648 PMC4377205__F4 Gene interaction pathway ENSG00000108798 ENSG00000196839 ENSG00000081277 ENSG00000057294 ENSG00000062485 PMC3425856__F4 CO prevents inflammatory responses via inhibition of NFKB signaling pathway ENSG00000172936 ENSG00000162692 PMC4788817__F6 Systemic pro-inflammatory response facilitates the development of cerebral edema during short hypoxia ENSG00000120088 ENSG00000136869 ENSG00000171885 PMC3388509__F2 Inflammasomes and Intestinal Tumorigenesis ENSG00000115415 ENSG00000168610 PMC9024123__F4 Network Pharmacology Analysis of Huangqi Jianzhong Tang Targets in Gastric Cancer ENSG00000105329 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000171791 ENSG00000112715 ENSG00000121879 ENSG00000164305 ENSG00000124762 ENSG00000110148 ENSG00000089685 ENSG00000136997 ENSG00000125538 ENSG00000113749 ENSG00000123374 ENSG00000185591 ENSG00000136869 ENSG00000139687 ENSG00000064012 ENSG00000140443 ENSG00000132906 ENSG00000087245 ENSG00000116044 ENSG00000131747 ENSG00000073756 ENSG00000177606 ENSG00000132646 ENSG00000100985 ENSG00000146648 PMC1502529__F6 Network modeling ENSG00000167601 ENSG00000110395 ENSG00000010810 ENSG00000105647 ENSG00000124181 ENSG00000160293 ENSG00000146648 ENSG00000089159 ENSG00000160691 ENSG00000179295 PMC4067728__F3 Molecular actions of 1,25(OH)2D3 in inflammation and energy homeostasis in adipocytes ENSG00000125538 ENSG00000136869 PMC11913854__F7 DHP-mediated apoptosis in HCT116 cells ENSG00000015285 ENSG00000168040 ENSG00000026103 PMC9514424__F7 Multiomic analysis of dark tea extract on glycolipid metabolic disorders in db/db mice ENSG00000226275 ENSG00000173599 ENSG00000198576 ENSG00000164136 ENSG00000038002 ENSG00000184207 ENSG00000186526 PMC11057055__F5 Identification of microRNA (miRNA) target genes ENSG00000154639 ENSG00000158195 ENSG00000180772 ENSG00000136531 ENSG00000133466 ENSG00000103241 ENSG00000134884 ENSG00000124762 ENSG00000166147 ENSG00000204262 ENSG00000170365 ENSG00000053747 ENSG00000038427 ENSG00000137203 ENSG00000169429 ENSG00000108821 ENSG00000087245 ENSG00000169554 ENSG00000148400 ENSG00000114416 ENSG00000100345 ENSG00000132170 ENSG00000143387 ENSG00000076604 ENSG00000120063 ENSG00000106617 ENSG00000117650 ENSG00000140285 ENSG00000146648 ENSG00000019991 ENSG00000152661 ENSG00000107562 ENSG00000065989 ENSG00000157933 ENSG00000197579 ENSG00000198793 ENSG00000020633 ENSG00000178209 ENSG00000150093 ENSG00000112715 ENSG00000137801 ENSG00000185591 ENSG00000087116 ENSG00000154342 ENSG00000134986 ENSG00000069329 ENSG00000073756 ENSG00000168610 ENSG00000140416 ENSG00000063176 ENSG00000182175 ENSG00000050165 ENSG00000019549 ENSG00000291748 ENSG00000040199 PMC4791802__F5 Transcriptome and metabolic flux analyses in the central carbon metabolism in ST687 and ST1 (non-producer) strains ENSG00000110711 ENSG00000100412 ENSG00000172005 ENSG00000084072 ENSG00000118898 ENSG00000060762 PMC3856398__F3 Ras-dependent versus Ras-independent extracellular signal-regulated kinase (ERK) signaling ENSG00000213658 ENSG00000149269 PMC8129499__F4 Coordinated Contribution of NADPH Oxidase- and Mitochondria-Derived Reactive Oxygen Species in Metabolic Syndrome and Its Implication in Renal Dysfunction ENSG00000162711 ENSG00000125538 PMC10821092__F1 Pharmacology of Veratrum californicum Alkaloids as Hedgehog Pathway Antagonists ENSG00000064309 ENSG00000172680 ENSG00000180447 ENSG00000106571 ENSG00000144857 ENSG00000166813 ENSG00000121067 ENSG00000128602 PMC4865099__F6 Cluster analysis indicates a potential pathway for MWCNT-induced fibrosis based on two distinct phases ENSG00000262406 ENSG00000108691 ENSG00000072694 ENSG00000118785 ENSG00000160013 ENSG00000163739 ENSG00000102970 ENSG00000277236 ENSG00000172936 ENSG00000118520 ENSG00000158869 PMC7641541__F2 CR2 site-targeted complement inhibitors ENSG00000203710 ENSG00000117322 PMC7641541__F3 Schematic graph showing that the complement system participates in the development of alcohol-induced liver disease ENSG00000134830 ENSG00000130649 ENSG00000136869 PMC3471675__F6 Structural Insights into the Common Gamma-Chain Family of Cytokines and Receptors from the Interleukin-7 Pathway ENSG00000100385 ENSG00000105639 PMC3985673__F5 Immune activation-related modules differentially correlated in NSCLC ENSG00000005471 ENSG00000095585 ENSG00000158234 ENSG00000152689 ENSG00000113263 ENSG00000151692 ENSG00000117322 ENSG00000035720 ENSG00000069667 PMC9318596__F2 Exploring the Role of Staphylococcus aureus in Inflammatory Diseases ENSG00000278718 ENSG00000162711 ENSG00000226275 ENSG00000137275 ENSG00000136869 ENSG00000168404 ENSG00000285379 ENSG00000164342 PMC6347688__F1 Social rank on blood cell gene expression and regulation vary by species and treatment according to two new studies in PNAS (, ) ENSG00000145321 ENSG00000172936 ENSG00000136869 ENSG00000276561 PMC12153588__F10 FGF downstream multiple signaling pathways ENSG00000106683 ENSG00000047849 ENSG00000182541 PMC7136425__F8 Compound BA-5 inhibits HSCs activation through blocking both TGFB1 and LPS-induced NFKB signaling pathways and further inhibits macrophage recruitment and activation ENSG00000095739 ENSG00000172936 ENSG00000136869 PMC6397540__F1 Proposed model of cell signaling associated with the ALK5-SMAD2/3 tumor-suppressive arm identified by Monsivais et al ENSG00000121989 ENSG00000170365 ENSG00000204217 ENSG00000114739 PMC4663246__F1 Cyclin D1-cyclin-dependent kinase 4/6-retinoblastoma 1 pathway ENSG00000135446 ENSG00000105810 ENSG00000139687 PMC6544049__F1 Circadian rhythms and memory formation ENSG00000137992 ENSG00000132326 PMC10125773__F5 TNFA signalling pathway ENSG00000102871 ENSG00000131323 ENSG00000168040 ENSG00000127191 PMC4762924__F1 Key pathways of glycogen synthesis and metabolism ENSG00000104812 ENSG00000068976 ENSG00000100994 ENSG00000111713 ENSG00000100504 PMC10125773__F3 IL-1A and IL-1B synthesis and signal transduction pathways ENSG00000115590 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC11522688__F9 Schematic illustrations of AMSC-EV and HUMSC-EV repairments on photoaging in vitro and in vivo via regulation of the TIMP1/Notch pathway (Created with BioRender ENSG00000178860 ENSG00000148400 ENSG00000096717 ENSG00000114315 ENSG00000137845 PMC3596529__F1 Intrinsic control of axon regeneration ENSG00000005882 ENSG00000198793 PMC8066579__F4 RLR, TLR and JAK-STAT signalling pathways and interference of signalling pathways by structural and non-structural proteins of coronaviruses ENSG00000135838 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000168610 ENSG00000164342 PMC6323178__F5 Compound K, a ginsenoside metabolite, plays an antiinflammatory role in macrophages by targeting the AKT1-mediated signaling pathway ENSG00000183735 ENSG00000291971 ENSG00000136869 PMC3070659__F1 Representative axon regeneration-regulating pathways discovered in genetic model organisms ENSG00000242689 PMC8577691__F3 STRING analysis of habenular proteins with increased levels after (−)-menthol exposure ENSG00000100519 ENSG00000113597 ENSG00000160551 ENSG00000169710 ENSG00000128050 ENSG00000101152 ENSG00000292191 ENSG00000111652 ENSG00000164978 ENSG00000128159 ENSG00000170043 ENSG00000176248 ENSG00000204843 ENSG00000164068 ENSG00000047230 ENSG00000146731 ENSG00000011485 ENSG00000166228 ENSG00000196712 ENSG00000157764 ENSG00000103035 ENSG00000138674 ENSG00000069869 ENSG00000176986 ENSG00000139287 ENSG00000120438 ENSG00000127824 ENSG00000108344 ENSG00000116096 PMC3889478__F1 Comparison of in vivo (left) and in vitro (right) signaling support to the intestinal stem cell ENSG00000138798 ENSG00000134245 ENSG00000277641 ENSG00000276799 PMC10982685__F1 Integration of Psat1 into glycolysis and the serine biosynthetic pathway and its contribution to additional signaling mechanisms ENSG00000128272 ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC3153486__F5 Impaired Vascular Contractility and Aortic Wall Degeneration in Fibulin-4 Deficient Mice: Effect of Angiotensin II Type 1 (AT1) Receptor Blockade ENSG00000105048 ENSG00000159173 ENSG00000196296 ENSG00000101470 ENSG00000143632 ENSG00000198363 PMC7583347__F1 S-Persulfidation: Chemistry, Chemical Biology, and Significance in Health and Disease ENSG00000181019 ENSG00000145321 ENSG00000023909 ENSG00000079999 PMC9704760__F5 An example paths-between query to find the two distinct directed links between two simple chemicals in the Urea cycle pathway with k = 7 ENSG00000036473 PMC8431939__F3 CD112R/CD112 axis: a breakthrough in cancer immunotherapy ENSG00000153283 ENSG00000181847 ENSG00000150637 PMC4434687__F4 Conversion of tabersonine to 3-hydroxy-2,3-dihydrotabersonine by the combined action of T3O and T3R enzymes ENSG00000154305 ENSG00000261857 PMC4582117__F8 Schematic of the VEGF-A/NRP1 signaling pathway to promote cancer cell proliferation PMC2671717__F7 Schematic Overview of Pyrimidine de Novo Synthesis, Salvage, and Degradation.Nucleotides synthesized de novo enter the nucleotide pool and become further converted to nucleic acids and other metabolic intermediates ENSG00000094841 PMC8130408__F1 Nicotinamide adenine dinucleotide (NAD+) biosynthetic pathway mediated by nicotinamide phosphoribosyltransferase (NAMPT) and circadian NAD+ oscillation ENSG00000105835 ENSG00000077463 ENSG00000096717 PMC11019464__F2 Chemoprophylaxis of precancerous lesions in patients who are at a high risk of developing colorectal cancer (Review) ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000154059 ENSG00000168036 PMC3525723__F4 Insulin signaling transduction ENSG00000138207 ENSG00000002330 ENSG00000198793 PMC7251756__F1 Glucose Metabolism and De Novo Lipogenesis (DNL) in Adipocytes ENSG00000131473 ENSG00000169710 ENSG00000062485 PMC4326637__F1 Biology of Advanced Uveal Melanoma and Next Steps for Clinical Therapeutics ENSG00000038382 ENSG00000198793 ENSG00000163914 PMC3989634__F2 Myeloid differentiation primary-response protein 88 (MyD88)-dependent and MyD88-independent TLR-4 signaling pathway ENSG00000183735 ENSG00000189403 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC11809005__F3 Reconstruction of the ginsenoside biosynthesis pathway in PN flowers, with expression profiles of structural genes across the six developmental stages ENSG00000160752 ENSG00000110921 ENSG00000113161 ENSG00000167508 PMC6723199__F1 The metabolic pathway of caffeine ENSG00000140505 ENSG00000130649 ENSG00000255974 PMC4758349__F2 AIM2 inflammasome in infection, cancer and autoimmunity: role in DNA sensing, inflammation and innate immunity ENSG00000154451 ENSG00000213928 ENSG00000164430 ENSG00000115415 ENSG00000163568 ENSG00000125538 ENSG00000125347 ENSG00000142166 PMC7566803__F7 IPA ATM-signaling pathway in (A) EFV treated MRC-5 and (B) A549 cells ENSG00000188486 ENSG00000149311 ENSG00000177606 ENSG00000197299 ENSG00000042088 PMC3359655__F1 Central IR/IGF-1 signaling ENSG00000124102 ENSG00000142192 ENSG00000005882 ENSG00000169047 ENSG00000133124 ENSG00000140443 PMC4317318__F2 Immunologic synapse ENSG00000134982 ENSG00000049768 PMC8698755__F5 Exploring the Value of BRD9 as a Biomarker, Therapeutic Target and Co-Target in Prostate Cancer ENSG00000274211 ENSG00000120833 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 ENSG00000105647 ENSG00000141564 ENSG00000171791 ENSG00000169032 ENSG00000121879 ENSG00000292210 ENSG00000171150 ENSG00000136997 ENSG00000180008 ENSG00000119487 ENSG00000157764 ENSG00000133056 ENSG00000196455 ENSG00000137193 ENSG00000105639 ENSG00000168610 ENSG00000138378 ENSG00000117020 ENSG00000105397 ENSG00000115415 ENSG00000173757 ENSG00000204673 ENSG00000171608 ENSG00000186654 ENSG00000198355 PMC6040266__F7 Mitochondrial sulfide-oxidizing pathway ENSG00000173156 PMC8422911__F10 cartoon illustrating the mechanisms by which deficiency of Adam15 leads to exaggerated COPD in mice ENSG00000143537 ENSG00000186810 ENSG00000198793 PMC2173906__F7 Hypothetical scheme of the mechanism by which Dkk1 promotes osteolytic lesions in vivo ENSG00000154342 ENSG00000168036 PMC10177541__F9 Effects and mechanisms of SQSTM1/p62 on migration and invasion of HCC ENSG00000087245 ENSG00000100985 ENSG00000079999 PMC4346117__F3 Evolutionary model of non-spatial clustered metastatic ovarian cancer ENSG00000095787 PMC8586976__F4 Green Synthesis of Gold Nanoparticles Using Plant Extracts as Beneficial Prospect for Cancer Theranostics ENSG00000123374 ENSG00000171791 PMC7882715__F3 Possible mechanism of polymorphism influences related with MAPK and PI3K/AKT cell signaling ENSG00000171234 ENSG00000165841 ENSG00000111962 PMC6740038__F3 The Keap1-Nrf2 signaling pathway ENSG00000100387 ENSG00000113558 ENSG00000079999 PMC7677104__F5 New, potential drugs targeting mainly immune cells, adapted and modified from Michalak ENSG00000198793 ENSG00000010671 PMC5818881__F9 SYK and downstream kinases are essential to drive inflammation and blistering in experimental epidermolysis bullosa acquisita (EBA) ENSG00000011422 ENSG00000158517 ENSG00000171051 PMC8584226__F3 Fat of the Gut: Epithelial Phospholipids in Inflammatory Bowel Diseases ENSG00000198793 ENSG00000173599 ENSG00000198670 PMC6740038__F1 The dual roles of Keap1-Nrf2 signaling pathway in pancreatic cancer ENSG00000100387 ENSG00000079999 PMC6425516__F1 Epigenetic regulation of peroxisome proliferator-activated receptorA (PPARA) in fatty acid oxidation (FAO) genes (A–C) and PPARA signaling to the FAO metabolome (D) ENSG00000135218 ENSG00000096717 PMC3103541__F8 Long-Term Continuous Corticosterone Treatment Decreases VEGF Receptor-2 Expression in Frontal Cortex ENSG00000198793 PMC9013863__F2 Micro RNAs in Regulating PI3K/AKT Signaling Pathways in Glioblastoma ENSG00000136997 ENSG00000115904 ENSG00000146648 PMC9013863__F3 Micro RNAs in Regulating PI3K/AKT Signaling Pathways in Glioblastoma ENSG00000164327 PMC2749675__F1 Scheme of the Wnt signaling pathway ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000100592 ENSG00000134982 ENSG00000168036 PMC9013863__F4 Micro RNAs in Regulating PI3K/AKT Signaling Pathways in Glioblastoma ENSG00000135446 ENSG00000105810 ENSG00000171791 ENSG00000168610 PMC6696356__F7 Scheme summarizing the protection of AB25–35-induced SH-SY5Y cell mitochondrial dysfunction by ginsenoside Re via inhibits ROS/ASK-1 dependent mitochondrial apoptosis pathway and activation of Nrf2-antioxidant response pathway ENSG00000178573 PMC7154970__F2 Regulatory roles of microRNAs in Tregs ENSG00000111537 ENSG00000102908 ENSG00000115415 ENSG00000196498 ENSG00000049768 ENSG00000168610 PMC6657153__F7 Schematic representation of Notch1-mediated regulation of Akt signaling disturbed by TDP-∆C protein ENSG00000148400 ENSG00000114315 PMC4332439__F7 Interplay model of Wnt/Beta-catenin, LPS/TLR4, and growth factors in ENS ENSG00000134982 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC4711038__F5 Altered gene expression in the JAK/STAT signaling pathway during diapause ENSG00000101361 PMC4711038__F9 Altered gene expression in the JNK signaling pathway during diapause ENSG00000175104 ENSG00000076604 PMC6740038__F4 Targeting Keap1-Nrf2 signaling pathway for pancreatic cancer prevention and therapy ENSG00000100387 ENSG00000113558 ENSG00000079999 PMC5179564__F7 Acetylation of central metabolic enzymes in desiccated embryos ENSG00000117054 ENSG00000161533 ENSG00000213614 ENSG00000169710 ENSG00000115361 ENSG00000168040 ENSG00000026103 PMC6174285__F1 Cyclic nucleotides signaling pathway in plant cells ENSG00000145321 ENSG00000164985 PMC5551552__F5 Schematic summarizing findings and proposed mechanism of placental lipid metabolism in obese women ENSG00000042832 ENSG00000105516 ENSG00000285482 PMC7825801__F2 Cholesterol synthesis pathway ENSG00000067064 ENSG00000110921 ENSG00000112972 ENSG00000116133 ENSG00000172893 ENSG00000113161 ENSG00000167508 PMC7411426__F2 Targets of hsa-miR-1307 ENSG00000171105 ENSG00000002330 ENSG00000070831 ENSG00000005882 ENSG00000150907 ENSG00000198793 ENSG00000169047 ENSG00000139515 ENSG00000232326 ENSG00000084733 ENSG00000077782 ENSG00000111737 PMC3762275__F2 Recognition of particulate and soluble Beta-glucans by dectin-1 and signal transduction in macrophages and DCs ENSG00000162711 ENSG00000187796 ENSG00000291971 ENSG00000173599 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC7825801__F3 Fatty acid metabolism ENSG00000255154 ENSG00000169710 PMC6323203__F1 Kyoto Encyclopedia of Genes and Genomes pathway analysis of differentially expressed proteins ENSG00000134982 ENSG00000105656 ENSG00000166278 PMC12210502__F7 The molecular interactions and signaling pathways involved in the association between TSC and renal cell carcinoma development (by Figdraw) ENSG00000112561 ENSG00000136235 PMC3590661__F1 Schematic overview of the impact of HDACi on DSB signalling, HR and NHEJ DNA repair pathways ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000051180 ENSG00000139618 PMC12210502__F8 The molecular interactions and signaling pathways involved in the association between TSC and renal angiomyolipomas development (by Figdraw) PMC12210502__F5 The molecular interactions and signaling pathways involved in the association between TSC and diabetic kidney disease development (by Figdraw) ENSG00000198793 ENSG00000155792 ENSG00000167965 PMC12210502__F6 The molecular interactions and signaling pathways involved in the association between TSC and renal cysts and polycystic kidney disease development (by Figdraw) ENSG00000008710 ENSG00000002330 ENSG00000217128 PMC12210502__F3 The molecular interactions and signaling pathways involved in the association between TSC and acute kidney injury development (by Figdraw) ENSG00000198793 ENSG00000155792 PMC12210502__F4 The molecular interactions and signaling pathways involved in the association between TSC and renal fibrosis and CKD development (by Figdraw) ENSG00000178860 ENSG00000198793 ENSG00000155792 ENSG00000167965 ENSG00000121236 PMC4061041__F6 ATM Regulates Insulin-Like Growth Factor 1-Secretory Clusterin (IGF-1-sCLU) Expression that Protects Cells against Senescence ENSG00000149311 ENSG00000140443 PMC12210502__F1 Patterns of TSC1/2 role in kidney disease (by Figdraw) ENSG00000008710 ENSG00000112561 ENSG00000217128 PMC12210502__F2 TSC1/2 signaling pathway (by Figdraw) ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC6437992__F1 ABT cell receptor (TCR) signaling pathway ENSG00000291603 ENSG00000213658 ENSG00000134982 ENSG00000115904 ENSG00000009790 ENSG00000124181 ENSG00000275122 ENSG00000141968 PMC4285849__F1 Impact of IBD genetic polymorphisms on dendritic cell function ENSG00000167207 PMC3078497__F1 Effector signaling pathways activated during ischemia preconditioning ENSG00000002330 ENSG00000168610 PMC3133356__F7 Model showing the role for Bmi1 in the DNA damage response pathway ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000168283 ENSG00000138385 ENSG00000112130 PMC8093290__F6 Ticagrelor inhibits the NLRP3 inflammasome to protect against inflammatory disease independent of the P2Y12 signaling pathway ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC8699297__F2 Impact of a Faulty Germinal Center Reaction on the Pathogenesis of Primary Diffuse Large B Cell Lymphoma of the Central Nervous System ENSG00000095585 ENSG00000105369 ENSG00000110395 ENSG00000186716 ENSG00000136997 ENSG00000196092 ENSG00000172936 ENSG00000010671 ENSG00000177565 ENSG00000198286 PMC7797784__F6 Proposed mechanism of action of JC-5411 via activation of Nrf2 pathway against arteriosclerosis ENSG00000162711 ENSG00000130164 ENSG00000125538 ENSG00000023909 ENSG00000079999 ENSG00000026103 PMC5179308__F7 Pathway to muscle fibrosis depends on myostatin stimulating the differentiation of fibro/adipogenic progenitor cells in chronic kidney disease ENSG00000078098 ENSG00000168610 PMC3612022__F6 Proposed synergistic pathway to mitotic cell death in cells treated with a combination of paclitaxel and gefitinib or the PLK1 inhibitor BI2536 ENSG00000166851 PMC2834195__F1 The circadian clock signaling pathway PMC10311893__F5 MRI-based breast cancer radiogenomics using RNA profiling: association with subtypes in a single-center prospective study ENSG00000120837 ENSG00000112964 ENSG00000196498 ENSG00000124205 ENSG00000127334 PMC4511633__F3 Hypothetical model of insulin resistance development in response to nutrition overload ENSG00000171105 ENSG00000169047 ENSG00000086991 PMC4783088__F2 Regulation of hepcidin antimicrobial peptide (HAMP) expression ENSG00000010704 ENSG00000106327 ENSG00000105697 ENSG00000130513 PMC5794012__F4 An overview of the main metabolic pathways affected by the storage lesion in RBCs during routine storage in the blood bank ENSG00000213658 ENSG00000172005 PMC12205195__F14 Comprehensive Genomic and Immunohistochemical Profiling to Predict Prognosis and Recurrence in Fertility-Sparing Therapy Based on Progesterone for Endometrial Carcinoma ENSG00000102871 ENSG00000198793 ENSG00000115138 ENSG00000127191 ENSG00000168610 PMC4810129__F2 Effects of virus mediated targeting of PDZ proteins often converge on the PI3K/AKT signal transduction pathway ENSG00000109062 ENSG00000198670 ENSG00000120913 PMC12205195__F15 Comprehensive Genomic and Immunohistochemical Profiling to Predict Prognosis and Recurrence in Fertility-Sparing Therapy Based on Progesterone for Endometrial Carcinoma ENSG00000169291 ENSG00000113070 ENSG00000198793 ENSG00000177606 ENSG00000146648 PMC6166676__F1 Study design ENSG00000179295 PMC8677728__F1 Targeting PI3K/Akt signal transduction for cancer therapy ENSG00000149311 ENSG00000175054 ENSG00000183735 ENSG00000186716 ENSG00000175104 ENSG00000146648 ENSG00000140443 PMC11005958__F1 Glucocorticoid signaling and the impact of high-fat diet on adipogenesis in vivo ENSG00000105894 ENSG00000134982 ENSG00000100345 ENSG00000168036 PMC8677728__F2 Targeting PI3K/Akt signal transduction for cancer therapy PMC8674309__F1 Antiviral Responses in Cancer: Boosting Antitumor Immunity Through Activation of Interferon Pathway in the Tumor Microenvironment ENSG00000213928 ENSG00000185436 ENSG00000173039 ENSG00000142166 ENSG00000150782 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000177606 ENSG00000125538 ENSG00000134070 ENSG00000136869 ENSG00000157625 ENSG00000243646 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC8674309__F2 Antiviral Responses in Cancer: Boosting Antitumor Immunity Through Activation of Interferon Pathway in the Tumor Microenvironment ENSG00000108691 ENSG00000111537 ENSG00000164136 PMC8674309__F3 Antiviral Responses in Cancer: Boosting Antitumor Immunity Through Activation of Interferon Pathway in the Tumor Microenvironment ENSG00000164430 ENSG00000115415 ENSG00000164342 PMC8674309__F4 Antiviral Responses in Cancer: Boosting Antitumor Immunity Through Activation of Interferon Pathway in the Tumor Microenvironment ENSG00000213928 ENSG00000111537 ENSG00000115415 ENSG00000276561 PMC5539397__F1 Effect of RBBP5 inhibition on glioblastoma ENSG00000183735 ENSG00000136869 PMC3023527__F7 Schematic summary of the results showing the consequences of mPGES-1 mediated PGE2synthesis for LPS-induced neuroinflammation ENSG00000125538 ENSG00000136869 PMC11673720__F2 A-to-I editing in mRNA coding region resulting in missense mutation ENSG00000122218 ENSG00000198793 ENSG00000160710 ENSG00000136068 PMC11673720__F4 Regulatory mechanisms of A-to-I editing on Alu ENSG00000088888 ENSG00000160710 ENSG00000067900 PMC4396475__F11 Casein kinase 1A–dependent feedback loop controls autophagy in RAS-driven cancers ENSG00000198793 PMC6627192__F4A Molecular Comparison of Imatinib-Naïve and Resistant Gastrointestinal Stromal Tumors: Differentially Expressed microRNAs and mRNAs ENSG00000137804 ENSG00000165891 ENSG00000125148 ENSG00000131153 ENSG00000132478 ENSG00000100526 ENSG00000145386 ENSG00000106546 ENSG00000069667 ENSG00000129173 ENSG00000112312 ENSG00000116641 ENSG00000137807 ENSG00000094804 ENSG00000065328 ENSG00000101003 ENSG00000171241 ENSG00000177606 ENSG00000157514 ENSG00000138180 ENSG00000080839 ENSG00000175305 PMC10178966__F3 Potential biotargets associated with the CI−AKI ENSG00000162711 ENSG00000137033 ENSG00000048052 ENSG00000136869 ENSG00000265972 ENSG00000142082 PMC11430655__F1 Interaction network constructed for genes involved in central carbon metabolism in cancer (hsa05230) limited to Homo sapiens (https://genemania ENSG00000262785 ENSG00000108515 ENSG00000151012 ENSG00000020633 ENSG00000103257 ENSG00000168003 ENSG00000130876 ENSG00000285516 ENSG00000172840 ENSG00000159216 ENSG00000132199 ENSG00000175745 ENSG00000188316 ENSG00000125246 ENSG00000090857 ENSG00000164708 PMC11430655__F2 Graph representing the interaction network of AGER (the gene encoding RAGE) with genes encoding RAGE ligands ENSG00000143546 ENSG00000169896 ENSG00000142973 ENSG00000109320 ENSG00000163221 ENSG00000173039 ENSG00000196154 ENSG00000189403 ENSG00000116489 ENSG00000168878 ENSG00000146648 ENSG00000089022 PMC5126201__F1 Adenosine pathway mediates immune suppression ENSG00000134982 ENSG00000196839 PMC84078__F7 Schematic of the influence of Notch on MEF2C and myogenic bHLH factor interactions ENSG00000291761 ENSG00000081189 PMC5719258__F5 An integrated model for valve development ENSG00000125266 ENSG00000285109 ENSG00000127528 ENSG00000168036 ENSG00000117707 ENSG00000089225 ENSG00000109814 ENSG00000196411 ENSG00000176692 ENSG00000261371 ENSG00000075275 ENSG00000179348 ENSG00000131196 PMC7414235__F1 Gastrointestinal symptoms in patients with coronavirus disease 2019 (COVID-19) ENSG00000131142 ENSG00000130234 ENSG00000198793 PMC10888452__F1 The PI3K/AKT signaling pathway and its activation ENSG00000002330 ENSG00000175104 PMC7933442__F1 Hypothetical model showing how alpha1-antitrypsin (AAT) may affect staurosporine (STS)-induced apoptosis and autophagy in NSCLC cells ENSG00000180210 ENSG00000198793 ENSG00000057663 ENSG00000084774 PMC11430655__F5 Graph representing the interaction networks of selected genes ENSG00000262785 ENSG00000108515 ENSG00000151012 ENSG00000005882 ENSG00000088305 ENSG00000198793 ENSG00000119969 ENSG00000076706 ENSG00000103257 ENSG00000142182 ENSG00000168003 ENSG00000285516 ENSG00000074800 ENSG00000175745 ENSG00000146083 ENSG00000277150 ENSG00000067955 ENSG00000263310 ENSG00000162755 ENSG00000130726 PMC3421232__F5 Network of 25 target genes and their interactive genes involved in regulating apoptosis and autophagy ENSG00000132906 ENSG00000002330 ENSG00000126775 ENSG00000196455 ENSG00000102871 ENSG00000198793 ENSG00000169710 ENSG00000168040 ENSG00000121879 ENSG00000164305 ENSG00000291983 ENSG00000134070 ENSG00000064012 PMC7796313__F1 Therapeutic targeting of TGFB in cancer: hacking a master switch of immune suppression PMC11430655__F4 Graph representing the interaction network of Diaph1 with proteins involved in cytoskeletal dynamics ENSG00000070087 ENSG00000172830 ENSG00000147202 ENSG00000163221 ENSG00000173039 ENSG00000108518 ENSG00000141298 ENSG00000114993 ENSG00000106683 ENSG00000100592 ENSG00000189403 ENSG00000084112 ENSG00000178568 ENSG00000196570 ENSG00000143632 PMC5328816__F6 A schematic representation of carbon metabolism in wine yeast, including glycolysis, pentose phosphate pathway and tricarboxylic acid (TCA) cycle ENSG00000074800 ENSG00000100412 ENSG00000146701 ENSG00000275544 PMC9035535__F1 Gut Microbial Community and Host Thermoregulation in Small Mammals ENSG00000136869 PMC6745797__F1 Major hallmark of immunosuppression in the TME through diverse pathways in EGFR-mutant NSCLC ENSG00000108691 ENSG00000109321 ENSG00000049768 ENSG00000146648 PMC7796135__F1 Inositol and Inositol Phosphates on Chemoprevention of Colitis-Induced Carcinogenesis ENSG00000115415 ENSG00000168610 PMC3508619__F1 MYC proteins and the p53/MDM2/p14ARFpathway PMC6745797__F2 Intrinsic cancer cell pathways mediate the regulation of PD-L1 expression and MHC in EGFR-mutant NSCLC ENSG00000105401 ENSG00000198793 ENSG00000136997 ENSG00000146648 PMC8784548__F1 Emerging Therapeutic Strategies for Attenuating Tubular EMT and Kidney Fibrosis by Targeting Wnt/Beta-Catenin Signaling ENSG00000169218 ENSG00000087245 ENSG00000281324 ENSG00000128512 ENSG00000137673 ENSG00000142178 ENSG00000162337 ENSG00000178573 ENSG00000134982 ENSG00000168036 ENSG00000001626 ENSG00000132693 PMC9064286__F3 Determinants of tumor sensitivity to GLS inhibitors ENSG00000151012 ENSG00000198793 ENSG00000173599 ENSG00000107485 ENSG00000115419 ENSG00000079999 PMC3213765__F12 Schematic of the sonic hedgehog signaling pathway ENSG00000164690 ENSG00000128602 PMC3089575__F8 Proposed interconnection between PE synthesis and conversion (PL interconversion triad) during LD biosynthesis ENSG00000042832 ENSG00000173599 ENSG00000133027 PMC3213765__F13 The sonic hedgehog signaling pathway in the primary cilium ENSG00000164690 ENSG00000128602 ENSG00000118971 PMC7985832__F2 TREX1 dysfunction triggers the cGAS-STING cytosolic DNA sensing pathway ENSG00000183735 ENSG00000164430 PMC3213765__F17 Wnt signaling pathway ENSG00000134982 ENSG00000168036 ENSG00000168646 PMC11003766__F5 The BTN2A1-BTN3A1-BTN3A2 complex regulation ENSG00000033011 ENSG00000128268 ENSG00000159216 ENSG00000292170 ENSG00000163933 ENSG00000214160 ENSG00000136908 ENSG00000166278 ENSG00000125347 ENSG00000244038 ENSG00000182858 ENSG00000000419 ENSG00000164414 ENSG00000214113 ENSG00000131446 ENSG00000134910 ENSG00000172269 ENSG00000171940 ENSG00000284501 ENSG00000117411 ENSG00000120697 ENSG00000167889 ENSG00000129255 ENSG00000167130 ENSG00000128039 ENSG00000141562 ENSG00000169599 ENSG00000095380 ENSG00000198162 ENSG00000103274 ENSG00000170191 ENSG00000182511 ENSG00000173540 ENSG00000111726 ENSG00000071073 ENSG00000086848 ENSG00000196547 ENSG00000168282 ENSG00000152127 ENSG00000100209 ENSG00000205301 ENSG00000144021 ENSG00000111885 ENSG00000137714 ENSG00000177239 ENSG00000112893 ENSG00000182050 ENSG00000089597 ENSG00000144057 ENSG00000101901 ENSG00000163902 ENSG00000073849 ENSG00000291973 ENSG00000104723 ENSG00000159921 ENSG00000139133 ENSG00000161513 ENSG00000159063 ENSG00000163527 ENSG00000088035 ENSG00000136003 PMC6996360__F3 Genes involved in hedgehog, Wnt, TGF‐B, and p53 signaling pathways were differentially expressed during developmental BA ENSG00000134982 ENSG00000164690 ENSG00000128602 PMC4298325__F6 A, Diagram of the prostaglandin synthesis pathway including relative expression values (arbitrary units) for synthetic enzymes and receptors from our previously reported microarray analysis of bovine growth plate chondrocytes () PMC3361623__F3 A New Framework for Understanding IRES-mediated Translation ENSG00000143486 ENSG00000144895 ENSG00000139726 PMC6996360__F2 Genes involved in Wnt, PI3K‐Akt, MAPK, TGF‐B, microsatellite instability, and p53 signaling pathways were differentially expressed during developmental BA ENSG00000132906 ENSG00000002330 ENSG00000134982 ENSG00000163914 ENSG00000168036 ENSG00000171791 ENSG00000095002 ENSG00000164305 PMC3361623__F1 A New Framework for Understanding IRES-mediated Translation ENSG00000106682 ENSG00000163435 ENSG00000100664 PMC8971815__F2 Intestinal Fibrosis in Inflammatory Bowel Disease and the Prospects of Mesenchymal Stem Cell Therapy ENSG00000168036 PMC4536527__F8 Stearic acid induces proinflammatory cytokine production partly through activation of lactate-HIF1A pathway in chondrocytes ENSG00000125538 ENSG00000136869 PMC10526873__F1 G Protein-Coupled Estrogen Receptor (GPER) in Vascular Pathology and Physiology ENSG00000291971 ENSG00000113070 ENSG00000138798 ENSG00000146648 PMC12035766__F1 Brief diagram of the mechanisms of molecular hydrogen ENSG00000128272 ENSG00000136869 ENSG00000100219 ENSG00000049768 ENSG00000175104 PMC10526873__F2 G Protein-Coupled Estrogen Receptor (GPER) in Vascular Pathology and Physiology ENSG00000291971 ENSG00000127528 ENSG00000146648 ENSG00000081189 PMC4569588__F4 Exploring the Altered Dynamics of Mammalian Central Carbon Metabolic Pathway in Cancer Cells: A Classical Control Theoretic Approach ENSG00000175054 ENSG00000292210 PMC4320069__F1 In Silico Functional Pathway Annotation of 86 Established Prostate Cancer Risk Variants ENSG00000136603 ENSG00000123700 ENSG00000066468 ENSG00000115648 ENSG00000170561 ENSG00000125398 ENSG00000206538 ENSG00000169032 ENSG00000167034 ENSG00000136826 ENSG00000089225 PMC8318284__F1 Network analysis of 12 miRNA-mRNA interaction pairs associated with OS in EOC patients ENSG00000105835 ENSG00000133110 ENSG00000138135 ENSG00000101000 ENSG00000113070 ENSG00000162772 ENSG00000134531 PMC3539150__F1 Schematic diagram illustrating the specific cascade and signaling pathway in LPS-primed macrophages stimulated with MSU, silica, or alum salt crystals ENSG00000125538 ENSG00000087842 PMC4320069__F4 In Silico Functional Pathway Annotation of 86 Established Prostate Cancer Risk Variants ENSG00000070193 ENSG00000263639 ENSG00000105176 ENSG00000164362 ENSG00000091409 ENSG00000013297 ENSG00000167034 ENSG00000064300 PMC12035766__F3 Molecular hydrogen alleviating IBD and intestinal injury ENSG00000278718 ENSG00000111537 ENSG00000128272 ENSG00000134982 ENSG00000100219 PMC4320069__F2 In Silico Functional Pathway Annotation of 86 Established Prostate Cancer Risk Variants ENSG00000070193 ENSG00000138795 ENSG00000137673 ENSG00000263639 ENSG00000130700 ENSG00000091409 ENSG00000167034 ENSG00000136826 ENSG00000066468 ENSG00000125398 ENSG00000136997 ENSG00000164362 ENSG00000013297 PMC12035766__F4 Molecular hydrogen reducing intestinal I/R injury ENSG00000278718 ENSG00000184216 PMC4320069__F3 In Silico Functional Pathway Annotation of 86 Established Prostate Cancer Risk Variants ENSG00000136603 ENSG00000070193 ENSG00000100290 ENSG00000115648 ENSG00000263639 ENSG00000137673 ENSG00000164362 ENSG00000013297 ENSG00000167034 ENSG00000198625 PMC12035766__F5 Molecular hydrogen inhibiting CRC growth PMC2798195__F9 Proposed mechanism for pathogenesis due to H ENSG00000174125 ENSG00000170458 ENSG00000136869 PMC6534778__F2 TLR4 signalling in hypertension and potential therapeutic targets ENSG00000183735 ENSG00000125538 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC5469213__F2 Tuberous sclerosis complex and mTOR pathway PMC6406290__F10 Scheme of proposed IS-induced apoptosis via ROS-NRF2 and MAPK signaling pathways in human astrocytes ENSG00000138166 ENSG00000291431 ENSG00000047936 PMC11834690__F1 Production of insulin and the classical insulin signaling pathway PMC7824062__F1 Competition of 2-OBA and Pyr in the l-threonine-overproducing E PMC8766339__F7 Case Report: Differential Genomics and Evolution of a Meningeal Melanoma Treated With Ipilimumab and Nivolumab ENSG00000126016 ENSG00000173674 ENSG00000198793 ENSG00000143751 ENSG00000168036 ENSG00000150457 ENSG00000165527 ENSG00000131023 ENSG00000168610 ENSG00000038382 ENSG00000115524 ENSG00000163914 ENSG00000164362 PMC3213765__F20 Shh and BMP signaling ENSG00000164690 ENSG00000198125 ENSG00000125968 ENSG00000172238 PMC2063755__F1 Signaling events during EMT ENSG00000057935 ENSG00000176692 ENSG00000138795 ENSG00000291971 ENSG00000196591 ENSG00000168036 PMC8781887__F1 Fission Yeast Cell Integrity Pathway: A Functional Hub for Cell Survival upon Stress and Beyond ENSG00000172409 ENSG00000124253 ENSG00000123268 PMC4887211__F9 Proposed working model for Fbxo21-mediated innate antiviral response ENSG00000100387 ENSG00000113558 ENSG00000285246 ENSG00000197442 PMC5234836__F5 Genome-Wide DNA Methylation Analysis of Chinese Patients with Systemic Lupus Erythematosus Identified Hypomethylation in Genes Related to the Type I Interferon Pathway ENSG00000213928 ENSG00000187608 ENSG00000089127 ENSG00000183486 ENSG00000157601 ENSG00000185745 ENSG00000185885 ENSG00000276561 ENSG00000135899 ENSG00000132530 ENSG00000134321 ENSG00000188313 ENSG00000163840 ENSG00000163235 ENSG00000108679 ENSG00000135114 ENSG00000111331 PMC4706383__F8 The proinflammatory role of HECTD2 in innate immunity and experimental lung injury ENSG00000033800 ENSG00000136869 PMC8855927__F1 Itaconate, Arginine, and Gamma-Aminobutyric Acid: A Host Metabolite Triad Protective Against Mycobacterial Infection ENSG00000162711 ENSG00000171444 ENSG00000136869 ENSG00000125347 PMC11017435__F1 NcRNAs: A synergistically antiapoptosis therapeutic tool in Alzheimer's disease ENSG00000102871 ENSG00000168040 ENSG00000026103 PMC9261345__F1 NAD-Linked Metabolism and Intervention in Short Telomere Syndromes and Murine Models of Telomere Dysfunction ENSG00000149311 ENSG00000175054 ENSG00000105835 ENSG00000096717 PMC6771568__F2 IGF signalling pathway alterations occurring in cisplatin‐resistant TGCT ENSG00000121879 ENSG00000140443 PMC10973144__F2 Protein glycosylation is closely interconnected with glycolysis and other metabolic pathways ENSG00000147162 ENSG00000198408 ENSG00000013375 PMC8033311__F1 Classical necroptosis signaling pathway initiated by the combining of TNF ligand and TNF receptor 1 ENSG00000102871 ENSG00000168040 ENSG00000168404 PMC10973144__F3 Pathological macrophages that promote inflammation or fibrosis have altered metabolism as a results of lung injury ENSG00000170458 ENSG00000133063 ENSG00000168610 PMC6755353__F1 The endosomal Toll-like receptor 7 (TLR7) in remodelling of the infarcted heart ENSG00000125538 ENSG00000189403 ENSG00000172936 ENSG00000184216 PMC5321214__F1 Coupling of toxic and pro-inflammatory lipids and innate immune response ENSG00000135218 ENSG00000172936 ENSG00000136869 PMC12230849__F4 MiRNAs regulate the proliferation and migration of VSMCs ENSG00000168036 ENSG00000081189 ENSG00000079999 PMC12230849__F5 Factors influencing VSMC apoptosis and their signal pathways ENSG00000120868 ENSG00000175104 PMC12230849__F6 Autophagy in VSMCs and its influencing factors ENSG00000126775 ENSG00000138166 ENSG00000198793 ENSG00000112561 ENSG00000066739 ENSG00000196689 ENSG00000057663 PMC11701794__F2 CEMIP affects the PI3K/AKT, EGFR, and Wnt/B‐catenin signaling pathways, which contribute to cancer progression by promoting cancer cell growth, angiogenesis, and proliferation, while also inhibiting cell death ENSG00000183734 ENSG00000151012 ENSG00000103888 ENSG00000146648 ENSG00000075213 PMC4891345__F1 Genes and biological processes shared in Parkinson’s disease (PD) and cancer ENSG00000198793 ENSG00000158828 PMC11701794__F3 CEMIP‐related hyaluronan (HA) degradation occurs through rapid vesicle endocytosis ENSG00000170961 ENSG00000026508 ENSG00000068001 ENSG00000103888 ENSG00000146648 PMC3982925__F1 PGD2 pathway in alopecia PMC6397983__F12 The insulin-like growth factor system role in PMSC differentiation into the skeletal muscle ENSG00000009709 ENSG00000122180 ENSG00000167779 ENSG00000169047 ENSG00000198793 ENSG00000135903 PMC4575611__F1 An outline of the inhibition of type I IFN signaling pathways by viral proteins of KSHV ENSG00000239732 ENSG00000164430 ENSG00000163565 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC3683896__F2 Extrinsic and intrinsic pathways of apoptosis ENSG00000120868 ENSG00000168040 PMC7959785__F2 Biosynthetic pathway of selenoprotein translation ENSG00000167468 ENSG00000179918 ENSG00000179988 PMC7924631__F1 Overnutrition leads to increased gluconeogenic gene expression by altering gut microbiota and lipopolysaccharide (LPS) production ENSG00000170458 ENSG00000150907 ENSG00000136869 ENSG00000100219 ENSG00000160741 PMC7722981__F2 Type 1 diabetes mellitus as a disease of the Beta-cell (do not blame the immune system?) ENSG00000169245 ENSG00000239732 ENSG00000115415 ENSG00000125538 ENSG00000139515 ENSG00000172936 ENSG00000136869 ENSG00000125347 ENSG00000164342 PMC7924631__F2 IRS acetylation by abnormal cytoplasm-appearing P300 causes insulin resistance ENSG00000150907 ENSG00000169047 ENSG00000160741 PMC5385611__F1 Cell migration induced by EGF via regulated alternative splicing of the Rho GTPase Rac1 ENSG00000138798 ENSG00000171621 ENSG00000146648 PMC5743619__F1 Schematic presentation of different pathways involved in PCa disparity.1 ENSG00000138798 ENSG00000198793 ENSG00000168610 PMC4527420__F1 A simplified representation of endocannabinoid synthesis and degradation pathway ENSG00000164535 ENSG00000117480 ENSG00000173599 ENSG00000134780 PMC10943956__F2 SASP regulation of aging intervertebral disc cells converges on the p53/p21 and p16/Rb pathways ENSG00000188486 ENSG00000149311 ENSG00000183735 ENSG00000164430 ENSG00000138385 PMC11500330__F3 Radiation-induced skin fibrosis and OS ENSG00000086991 ENSG00000185591 PMC2734563__F2 Possible mechanisms of UbcH7 regulation of Chk1 levels sand S phase ENSG00000012048 ENSG00000166508 PMC7029350__F8 Both extrinsic and intrinsic pathways converge in the same terminal execution pathway, which is initiated by the cleavage of caspase-3 ENSG00000102871 ENSG00000168040 PMC3721230__F1 Mechanisms of action of lipopolysaccharide (LPS) as a sepsis inducer ENSG00000170458 ENSG00000172936 PMC7382779__F4 Functional Relationships by Gene Ontology (GO) Enrichment Analysis of Protein Regulation Networks and Phosphorylation Regulation Networks ENSG00000074800 ENSG00000034533 PMC7029350__F6 Wnt signaling is regulated by the cytoplasmic Beta-catenin destruction complex, which consists of the core proteins AXIN, adenomatous polyposis coli, casein kinase 1, and glycogen synthase kinase 3 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4530250__F2 GDF-15 regulates signaling pathways essential for cardioprotection ENSG00000137834 ENSG00000002330 ENSG00000168036 ENSG00000146648 PMC3729336__F1 Schematic overview of the kynurenine (KYN) pathway ENSG00000188676 PMC7029350__F5 Class I PI3Ks activated by receptor tyrosine kinases, such as epidermal growth factor receptor, can phosphorylate PI 4,5-bisphosphate to yield PI 3,4,5-triphosphate in the cell membrane ENSG00000002330 PMC2733936__F1 Targeting the ASK1/MKK4/JNK pathway upstream of mitochondrial prodeath signaling ENSG00000002330 ENSG00000127191 PMC8634471__F2 Receptor Tyrosine Kinases and Their Signaling Pathways as Therapeutic Targets of Curcumin in Cancer ENSG00000136869 ENSG00000146648 ENSG00000140443 PMC7156217__F9 Possible model for the CD40 signaling mechanisms ENSG00000183735 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC6978796__F3 Roles of defective mitophagy in AD with a vicious cycle between them ENSG00000118369 ENSG00000143799 ENSG00000135655 ENSG00000123240 ENSG00000135093 PMC6755251__F4 T-cell receptor signaling pathway ENSG00000110395 ENSG00000213658 ENSG00000010810 ENSG00000135446 ENSG00000113520 ENSG00000113263 PMC6054540__F9 Regulation of hepcidin in breast cancer spheroids ENSG00000168610 PMC6834141__F2 Simplified overview of the signaling pathways in the target cells presented in this review that are relevant for the development of a pharmacological therapy rationale ENSG00000128342 ENSG00000168040 ENSG00000168610 PMC7343963__F6 Construction of correlation network ENSG00000128016 PMC3645912__F1 Induction and maintenance of IDO in dendritic cells ENSG00000049768 ENSG00000168610 ENSG00000106546 PMC11948861__F3 Autophagy-mediated ferroptosis ENSG00000228716 ENSG00000132471 ENSG00000145495 ENSG00000128272 ENSG00000138449 ENSG00000151012 ENSG00000170558 ENSG00000167468 ENSG00000198793 ENSG00000112561 ENSG00000057663 ENSG00000198925 PMC11948861__F4 Autophagy-mediated other forms of RCD ENSG00000143799 ENSG00000152348 ENSG00000198382 ENSG00000163625 ENSG00000134982 ENSG00000198793 ENSG00000189403 ENSG00000145782 ENSG00000057663 PMC2780394__F7 The signaling network of differentially expressed proteins ENSG00000004660 ENSG00000002330 ENSG00000070831 ENSG00000160180 ENSG00000135446 ENSG00000173039 ENSG00000168036 ENSG00000123374 ENSG00000149554 PMC3206090__F5 Convergent pathogenic pathways in Alzheimer’s and Huntington disease: Shared targets for drug development ENSG00000198793 ENSG00000197386 PMC3206090__F2 Convergent pathogenic pathways in Alzheimer’s and Huntington disease: Shared targets for drug development ENSG00000142192 ENSG00000173805 ENSG00000197386 PMC12223711__F3 Function of NDR1 and other NHLs in PTI and ETI responses ENSG00000291931 PMC5629826__F1 Dopaminergic pathway genes and serotonergic pathway genes ENSG00000276825 ENSG00000184845 ENSG00000169676 ENSG00000102468 ENSG00000149295 PMC3730337__F1 HDACi and DNMTi target the MM cell ENSG00000149311 ENSG00000175054 ENSG00000134982 PMC2974943__F2 Intracellular signaling pathway within cranial neural crest cells mediated by endothelin-1 (Edn1) ENSG00000140564 ENSG00000145194 ENSG00000117298 PMC8204192__F4 Genome Analysis of a Verrucomicrobial Endosymbiont With a Tiny Genome Discovered in an Antarctic Lake ENSG00000039537 ENSG00000182511 ENSG00000167900 PMC8533927__F1 Escaping KRAS: Gaining Autonomy and Resistance to KRAS Inhibition in KRAS Mutant Cancers ENSG00000079999 PMC8533927__F2 Escaping KRAS: Gaining Autonomy and Resistance to KRAS Inhibition in KRAS Mutant Cancers ENSG00000065361 ENSG00000087586 ENSG00000077782 ENSG00000140443 PMC11048239__F1 Flux-independent signaling pathways activated by AMPARs in neurons ENSG00000198576 PMC8210594__F1 Microbial and genetic-based framework identifies drug targets in inflammatory bowel disease ENSG00000157404 ENSG00000164430 ENSG00000159216 ENSG00000163599 ENSG00000049768 PMC6567134__F8 Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation ENSG00000135218 ENSG00000042832 ENSG00000110244 ENSG00000187288 ENSG00000134324 ENSG00000169710 ENSG00000124003 PMC4522390__F1 The Repeat Expansion Diseases: the dark side of DNA repair? ENSG00000105486 ENSG00000140398 ENSG00000177084 ENSG00000136936 PMC8353504__F1 Hypothalamic de novo ceramides synthesis in obesity and associated metabolic disorders PMC5618525__F3 Signaling events downstream of IL7R (depicted in purple) and the pre-BCR (depicted in black and red) involved in the regulation of RAG1/2 expression and Ig light chain recombination ENSG00000166349 ENSG00000112576 ENSG00000150907 ENSG00000171791 ENSG00000105639 ENSG00000168685 PMC6263343__F3 Heme biosynthesis ENSG00000144410 ENSG00000066926 ENSG00000126088 PMC11048239__F4 Flux-independent signaling by NMDARs in neurons ENSG00000291971 ENSG00000198929 ENSG00000110218 ENSG00000196689 PMC3682694__F1 Roles of molecules explained in this review in signal transduction ENSG00000149311 ENSG00000175054 ENSG00000008710 ENSG00000134086 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000138777 ENSG00000196712 PMC6274950__F10 Correlation networks of main potential biomarkers in response to T2DM rats ENSG00000125538 ENSG00000132693 PMC8692454__F4 Reconstruction of the Rhodotorula frigidialcoholis major carbohydrate metabolic pathways mapped with transcriptomic data ENSG00000131473 ENSG00000143252 ENSG00000140263 ENSG00000117118 ENSG00000173599 ENSG00000153574 ENSG00000105953 ENSG00000093217 ENSG00000146701 ENSG00000091140 ENSG00000062485 PMC7794017__F1 Canonical and non-canonical WNT pathways ENSG00000281324 ENSG00000137673 ENSG00000162337 ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC3243790__F1 Regulation of ABCA1 Functions by Signaling Pathways ENSG00000168610 PMC2855687__F1 The kynurenine pathway with relevant regulatory components, summarizing gene expression and metabolite changes previously identified for schizophrenia in the frontal and anterior cingulate cortex ENSG00000262635 ENSG00000162882 ENSG00000176136 ENSG00000128285 PMC4135535__F3 Challenges in Vaccination of Neonates, Infants and Young Children ENSG00000186716 ENSG00000197943 PMC2607114__F1 TFPI anti-coagulant and anti-inflammatory activities ENSG00000003436 ENSG00000291971 PMC8228391__F1 Bilirubin: A Promising Therapy for Parkinson’s Disease ENSG00000158828 ENSG00000138760 PMC5844144__F1 Ferroptosis-associated metabolic networks ENSG00000065833 ENSG00000167468 ENSG00000197429 ENSG00000111684 PMC9657658__F2 Inflammatory Mechanism of Brucella Infection in Placental Trophoblast Cells ENSG00000167207 ENSG00000127191 ENSG00000106100 PMC3048826__F12 Signaling pathway of HMGB1-mediated ischemia reperfusion injury ENSG00000239732 ENSG00000070831 ENSG00000291971 ENSG00000163914 ENSG00000189403 PMC7408018__F1 Autophagy pathway including the convergence of the endocytic pathway ENSG00000177169 ENSG00000123395 ENSG00000126775 ENSG00000196455 ENSG00000023287 ENSG00000198793 ENSG00000005893 ENSG00000145782 PMC7520643__F1 Protein kinase B signaling pathway ENSG00000181019 PMC7300250__F1 Signaling pathways regulated by Shp1 ENSG00000291971 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000171791 ENSG00000168610 PMC2873801__F4 Relationships between differentially expressed miRNAs, putative target genes, and functions ENSG00000145632 ENSG00000291823 ENSG00000128322 ENSG00000198796 ENSG00000171723 ENSG00000164164 ENSG00000122224 ENSG00000148926 ENSG00000178104 ENSG00000162772 ENSG00000171791 ENSG00000112992 ENSG00000111348 ENSG00000101680 ENSG00000178445 ENSG00000103811 ENSG00000070444 ENSG00000124479 ENSG00000130164 ENSG00000166670 ENSG00000163435 ENSG00000164056 ENSG00000156127 ENSG00000123609 ENSG00000133805 PMC7408018__F2 ER stress unfolded protein response (UPR) pathways triggering autophagy ENSG00000128272 ENSG00000198793 ENSG00000100219 ENSG00000171791 PMC6858516__F5 Towards precision oncology in advanced prostate cancer ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000139687 PMC9636677__F6 Irradiation-induced exosomal HMGB1 to confer radioresistance via the PI3K/AKT/FOXO3A signaling pathway in ESCC ENSG00000134057 ENSG00000189403 ENSG00000171791 PMC6858516__F6 Towards precision oncology in advanced prostate cancer ENSG00000087586 ENSG00000139687 PMC6978262__F1 Signaling transduction pathways of regulating autophagy ENSG00000177169 ENSG00000092439 ENSG00000198793 PMC11055934__F1 Depicts the eicosanoid inflammatory pathway ENSG00000138115 ENSG00000187048 ENSG00000120915 ENSG00000145321 ENSG00000124212 PMC6858516__F3 Towards precision oncology in advanced prostate cancer PMC6858516__F4 Towards precision oncology in advanced prostate cancer ENSG00000167258 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000095002 ENSG00000122512 ENSG00000139618 ENSG00000183765 PMC8468925__F3 Targeting the p53 Pathway in CLL: State of the Art and Future Perspectives ENSG00000149311 ENSG00000175054 PMC6858516__F1 Towards precision oncology in advanced prostate cancer ENSG00000167258 ENSG00000149311 ENSG00000135446 ENSG00000105810 ENSG00000139687 ENSG00000139618 ENSG00000183765 PMC4791795__F2 Select Biological Pathways Significantly Associated with Differentially Regulated Genes ENSG00000087095 ENSG00000226275 ENSG00000138798 ENSG00000111837 PMC11055934__F4 illustrates the various components of the p53 regulatory pathway and relevant polymorphisms associated with ISFO ENSG00000087245 ENSG00000141499 ENSG00000100985 ENSG00000253352 PMC2768529__F8 Proposed interplay between IL-15 and TNFA signaling in skeletal muscle ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000084774 PMC4694985__F3 The respective drug targets in the overall architecture of molecular interactions for the top pathways correlating with response to Pazopanib A ENSG00000149311 ENSG00000128272 ENSG00000198793 ENSG00000169047 ENSG00000177606 ENSG00000169710 ENSG00000051180 PMC11210914__F5 Mitophagy in ferroptosis ENSG00000158828 ENSG00000069509 ENSG00000181867 PMC7744479__F2 Lymphoma induced angiogenesis in LNs and participating immune cells ENSG00000186810 ENSG00000226275 ENSG00000137077 ENSG00000138755 ENSG00000105656 ENSG00000026508 ENSG00000126353 ENSG00000100985 ENSG00000112715 ENSG00000150630 PMC11210914__F7 CMA- or TAX1BP1-mediated GPX4 degradation in ferroptosis ENSG00000151012 ENSG00000167468 ENSG00000198793 ENSG00000005893 PMC5217035__F7 Enhanced cytotoxicity of reovirus and radiotherapy in melanoma cells is mediated through increased viral replication and mitochondrial apoptotic signalling ENSG00000127948 PMC3936121__F7 MUC4 mucin mediates gemcitabine resistance of human pancreatic cancer cells via the Concentrative Nucleoside Transporter family ENSG00000167325 ENSG00000145113 PMC3403823__F1 TLR-induced corneal inflammation ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000164342 PMC8591223__F10 Low Expression of SLC7A11 Confers Drug Resistance and Worse Survival in Ovarian Cancer via Inhibition of Cell Autophagy as a Competing Endogenous RNA ENSG00000177169 ENSG00000198382 ENSG00000083290 ENSG00000023287 ENSG00000198793 ENSG00000005893 ENSG00000148572 ENSG00000128829 ENSG00000172007 ENSG00000145782 ENSG00000057663 ENSG00000136874 PMC8231924__F1 MAGI1, a Scaffold Protein with Tumor Suppressive and Vascular Functions ENSG00000151276 ENSG00000149564 ENSG00000107263 ENSG00000130402 ENSG00000087077 ENSG00000114019 PMC2951022__F1 Toll-like receptor (TLR) signaling pathways ENSG00000174125 ENSG00000183735 ENSG00000170458 ENSG00000187554 ENSG00000173039 ENSG00000172936 ENSG00000136869 ENSG00000130159 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC3292584__F4 Differential gene expression in the TLR signalling pathway ENSG00000104365 ENSG00000154589 ENSG00000100906 ENSG00000170458 ENSG00000177606 ENSG00000172936 ENSG00000136869 ENSG00000213341 ENSG00000130159 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC5659172__F3 Trioxacarcin revealing a different starter unit and complex tailoring steps for type II polyketide synthase ENSG00000166278 PMC7968485__F1 Ferroptosis: Regulated Cell Death ENSG00000196839 ENSG00000167468 ENSG00000111684 PMC6978262__F2 Related miRNAs and target genes/pathways that regulate autophagy ENSG00000152348 ENSG00000198793 ENSG00000096717 ENSG00000145782 ENSG00000057663 ENSG00000198925 PMC5630287__F6 Beta-NAD+ salvage pathway and PKC-mediated signaling influence localized PARP-1 activity and CTCF Poly(ADP)ribosylation ENSG00000105835 ENSG00000157064 ENSG00000102974 PMC2683584__F1 Control of Cell Number in the Sexually Dimorphic Brain and Spinal Cord ENSG00000168040 PMC3675828__F3 Abundance distribution of cell cycle proteins ENSG00000276618 ENSG00000260314 ENSG00000113456 ENSG00000100387 ENSG00000134982 ENSG00000113558 ENSG00000115266 ENSG00000115942 ENSG00000135336 ENSG00000164754 ENSG00000138777 PMC5876639__F1 Involvement of nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) in DNA damage response pathway ENSG00000149311 ENSG00000175054 PMC7348182__F7 Results of RT‐qPCR and ELISA validation for cAMP and Rap1 signal pathway ENSG00000164742 ENSG00000197299 PMC7148637__F40 RV regulation of the IFN amplification pathway ENSG00000213928 ENSG00000115415 ENSG00000185436 ENSG00000027697 ENSG00000276561 ENSG00000142166 PMC8750433__F2 Multifactorial Mechanism of Sarcopenia and Sarcopenic Obesity. Role of Physical Exercise, Microbiota and Myokines ENSG00000198793 PMC4472122__F1 Signaling pathways activated by FGF/FGFR ENSG00000115415 ENSG00000291971 PMC8489124__F5 Bai-He-Gu-Jin-Tang formula suppresses lung cancer via AKT/GSK3B/Beta-catenin and induces autophagy via the AMPK/mTORC1/ULK1 signaling pathway ENSG00000142192 ENSG00000179091 PMC11210914__F1 Ferroptosis ENSG00000116044 ENSG00000151012 ENSG00000167468 ENSG00000072274 ENSG00000008394 ENSG00000042286 ENSG00000102967 ENSG00000127948 PMC8798099__F4 Gene network screening of bladder cancer via modular analysis ENSG00000112977 ENSG00000105664 ENSG00000164362 ENSG00000127948 ENSG00000139618 PMC11257964__F4 Targeting PANoptosis for cancer therapy ENSG00000278718 ENSG00000162711 ENSG00000124256 ENSG00000137275 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC11257964__F1 Molecular machinery of apoptosis, pyroptosis, and necroptosis ENSG00000278718 ENSG00000162711 ENSG00000137275 ENSG00000102871 ENSG00000091106 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 ENSG00000026103 PMC3011268__F2 Regulation of Wnt signaling in Xenopus CNC ENSG00000038382 ENSG00000039537 ENSG00000112655 PMC3253010__F3 A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype ENSG00000117020 ENSG00000142798 ENSG00000010810 ENSG00000113140 ENSG00000128052 ENSG00000125810 ENSG00000154721 ENSG00000004399 ENSG00000087303 ENSG00000111348 ENSG00000158445 ENSG00000116962 PMC4830852__F1 Proteins encoded by genes analyzed in this study in the inhibition of the Wnt signaling ENSG00000164736 ENSG00000276644 ENSG00000168036 ENSG00000104332 ENSG00000156475 PMC7139457__F1 Intrinsic apoptotic pathway and interactions between pro- and anti-apoptotic B-cell lymphoma 2 (BCL-2) family members ENSG00000100290 ENSG00000002330 ENSG00000135116 ENSG00000104081 PMC4561407__F4 Translational control by ERK and mTOR ENSG00000198793 ENSG00000167658 PMC3755409__F6 Scheme of the andrographolide regulatory pathway ENSG00000128052 PMC9437628__F4 System level modeling and analysis of TNFA mediated sphingolipid signaling pathway in neurological disorders for the prediction of therapeutic targets ENSG00000102871 ENSG00000168040 ENSG00000112186 ENSG00000127191 ENSG00000164305 PMC11050296__F10 Scheme showing the mechanism of olive-derived secoiridoids that regulate melanogenesis signaling pathway ENSG00000168036 ENSG00000080166 PMC6020395__F1 The vitamin-D metabolic pathway ENSG00000111012 ENSG00000019186 ENSG00000186104 ENSG00000135929 PMC8296701__F1 Genistein as a regulator of signaling pathways and microRNAs in different types of cancers ENSG00000149311 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC9437628__F2 System level modeling and analysis of TNFA mediated sphingolipid signaling pathway in neurological disorders for the prediction of therapeutic targets ENSG00000132906 ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000064012 ENSG00000164305 PMC3536145__F7 GXM-mediated inhibition of LPS-induced signal ENSG00000172936 ENSG00000136869 PMC11241568__F2 The JAK–STAT Pathway in Childhood B-Cell Acute Lymphoblastic Leukemia ENSG00000115415 ENSG00000145777 ENSG00000292363 ENSG00000105639 ENSG00000168610 PMC4761208__F5 Pathway network of the 22 TSGs based on GeneMANIA ENSG00000145632 ENSG00000084093 ENSG00000101109 ENSG00000134982 ENSG00000168040 PMC5915057__F4 2’-Hydroxyflavanone effectively targets RLIP76-mediated drug transport and regulates critical signaling networks in breast cancer ENSG00000087510 ENSG00000070831 ENSG00000138798 ENSG00000120875 ENSG00000169047 ENSG00000150093 ENSG00000105647 ENSG00000010278 ENSG00000168811 ENSG00000145431 ENSG00000184602 ENSG00000175130 ENSG00000196557 ENSG00000140937 ENSG00000254726 ENSG00000156299 ENSG00000188404 ENSG00000100219 ENSG00000120868 ENSG00000170571 ENSG00000162892 ENSG00000126458 ENSG00000182578 ENSG00000074590 ENSG00000133056 ENSG00000134986 ENSG00000124766 ENSG00000116717 ENSG00000163412 ENSG00000261371 ENSG00000120899 ENSG00000170458 ENSG00000213694 ENSG00000134243 PMC5915057__F5 2’-Hydroxyflavanone effectively targets RLIP76-mediated drug transport and regulates critical signaling networks in breast cancer ENSG00000147862 ENSG00000178999 ENSG00000159388 ENSG00000077514 ENSG00000146143 ENSG00000112118 ENSG00000120885 ENSG00000198056 ENSG00000136826 ENSG00000157184 ENSG00000138778 ENSG00000177426 ENSG00000156103 ENSG00000172216 ENSG00000292234 ENSG00000107537 ENSG00000244405 ENSG00000069812 ENSG00000136997 ENSG00000146386 ENSG00000179111 ENSG00000014138 ENSG00000140859 ENSG00000100219 ENSG00000177508 ENSG00000183779 ENSG00000134548 ENSG00000196712 ENSG00000113645 ENSG00000063978 ENSG00000186529 ENSG00000117399 ENSG00000111145 ENSG00000132646 ENSG00000112208 ENSG00000131153 ENSG00000105656 ENSG00000077150 ENSG00000125968 ENSG00000140416 ENSG00000172667 ENSG00000108691 ENSG00000128272 ENSG00000177606 ENSG00000161513 ENSG00000197299 ENSG00000133119 ENSG00000116761 ENSG00000175305 PMC6406640__F3 Schematic representation of gene silencing by siRNAs ENSG00000113360 ENSG00000134698 ENSG00000123908 PMC5690305__F1 Simplified metabolic pathway of thiopurines ENSG00000042832 ENSG00000137364 PMC3478260__F4 signaling pathways triggered by L1CAM ENSG00000291971 ENSG00000198910 PMC5094313__F5 Metabolic pathways that may be affected by lactate flooding of brain after traumatic brain injury ENSG00000122966 ENSG00000173599 PMC8122033__F4 CGAMP transport in the tumor microenvironment ENSG00000164430 ENSG00000173638 PMC8055391__F7 Follistatin-Like 1 Attenuation Suppresses Intervertebral Disc Degeneration in Mice through Interacting with TNFA and Smad Signaling Pathway ENSG00000170365 ENSG00000154736 ENSG00000163430 ENSG00000136869 ENSG00000128928 PMC8616527__F3 Willin/FRMD6: A Multi-Functional Neuronal Protein Associated with Alzheimer’s Disease ENSG00000070831 ENSG00000163914 ENSG00000139926 ENSG00000127948 PMC7478169__F1 Normal downstream pathway of TSC1 and TSC2, and its gene products ENSG00000167965 PMC9388335__F7 Inhibition of Kruppel-like factor 7 attenuates cell proliferation and inflammation of fibroblast-like synoviocytes in rheumatoid arthritis through nuclear factor KB and mitogen-activated protein kinase signaling pathway ENSG00000118263 ENSG00000125538 PMC3899964__F1 Discriminating Gene Expression Signature of Radiation-Induced Thyroid Tumors after Either External Exposure or Internal Contamination ENSG00000166869 ENSG00000107562 ENSG00000169071 ENSG00000070831 ENSG00000181274 ENSG00000175592 ENSG00000120885 ENSG00000157240 ENSG00000164615 ENSG00000163914 ENSG00000125686 ENSG00000165879 ENSG00000154310 ENSG00000072135 ENSG00000185269 ENSG00000155760 ENSG00000155657 ENSG00000101333 ENSG00000165322 ENSG00000164252 ENSG00000087095 ENSG00000087245 ENSG00000291745 ENSG00000064309 ENSG00000163947 ENSG00000123091 ENSG00000154358 ENSG00000109321 ENSG00000213390 ENSG00000196562 ENSG00000106483 ENSG00000124205 ENSG00000119048 ENSG00000180447 ENSG00000117122 ENSG00000168066 ENSG00000163235 ENSG00000124882 ENSG00000015285 ENSG00000171848 ENSG00000026508 ENSG00000164690 ENSG00000128602 ENSG00000146648 PMC6273696__F30 mTOR signaling pathway was regulated by vancomycin in HK-2 cells ENSG00000163435 ENSG00000171105 ENSG00000198793 ENSG00000173599 PMC3407412__F3 Tannerella forsythia infection-induced calvarial bone and soft tissue transcriptional profiles ENSG00000081237 ENSG00000134982 ENSG00000197471 ENSG00000163599 ENSG00000150637 PMC3407412__F5 Tannerella forsythia infection-induced calvarial bone and soft tissue transcriptional profiles ENSG00000169291 ENSG00000002330 PMC2547860__F6 Networks among genes involved in milk fat synthesis ENSG00000151726 ENSG00000110048 ENSG00000151365 ENSG00000186480 ENSG00000169710 ENSG00000099194 ENSG00000118777 ENSG00000158125 ENSG00000109819 ENSG00000063176 ENSG00000134824 ENSG00000149485 ENSG00000134324 ENSG00000285482 ENSG00000198911 PMC8957998__F8 Inspiration for COVID-19 Treatment: Network Analysis and Experimental Validation of Baicalin for Cytokine Storm ENSG00000168530 ENSG00000065833 ENSG00000111837 ENSG00000198517 ENSG00000073910 ENSG00000127191 ENSG00000174611 ENSG00000062485 PMC4174766__F2 Intracellular TLR signaling and trafficking in pDCs ENSG00000239732 ENSG00000172936 ENSG00000131323 ENSG00000110057 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC5549971__F7 Spheroid growth in ovarian cancer alters transcriptome responses for stress pathways and epigenetic responses ENSG00000182481 ENSG00000012048 ENSG00000084676 ENSG00000108773 ENSG00000196591 ENSG00000162521 ENSG00000196498 ENSG00000150459 ENSG00000096717 ENSG00000169375 ENSG00000114166 ENSG00000164105 PMC5686110__F2 Signaling pathway of breast cancer download from KEGG website– with targeted genes and pathways from germacrone, curdione, and furanodiene ENSG00000157404 ENSG00000134982 ENSG00000162924 PMC6365104__F1 Main regulation modes of copper transporters in human cells ENSG00000177556 ENSG00000185591 PMC6273696__F36 ER stress signaling pathway was regulated by vancomycin in HK-2 cells ENSG00000132906 ENSG00000291983 ENSG00000128272 ENSG00000100219 ENSG00000127191 PMC6273696__F37 ERK-MAPK signaling pathway was regulated by vancomycin in HK-2 cells ENSG00000172680 ENSG00000002330 ENSG00000291971 ENSG00000136997 ENSG00000131196 ENSG00000089159 PMC5549971__F4 Spheroid growth in ovarian cancer alters transcriptome responses for stress pathways and epigenetic responses ENSG00000047410 ENSG00000112964 ENSG00000001167 ENSG00000058085 ENSG00000138798 ENSG00000198793 ENSG00000173039 ENSG00000136352 ENSG00000162772 ENSG00000164120 ENSG00000104368 ENSG00000158125 ENSG00000038427 ENSG00000177606 ENSG00000104447 PMC6273696__F34 Remodeling of epithelial adherent junction signaling pathway was regulated by vancomycin in HK-2 cells ENSG00000019991 ENSG00000134982 ENSG00000006451 PMC6273696__F35 UPR signaling pathway was regulated by vancomycin in HK-2 cells ENSG00000128272 ENSG00000159461 ENSG00000165280 ENSG00000127022 ENSG00000100219 ENSG00000171791 ENSG00000127191 ENSG00000135506 PMC6273696__F33 Tight junction signaling pathway was regulated by vancomycin in HK-2 cells ENSG00000147044 ENSG00000148798 ENSG00000143375 PMC10520362__F3 Mammalian Intestinal Development and Differentiation—The State of the Art ENSG00000050165 ENSG00000134245 ENSG00000146374 PMC5541263__F8 Retinoic acid directs breast cancer cell state changes through regulation of TET2-PKCζ pathway ENSG00000133961 PMC6284756__F9 Regulatory effects of miR-1292 on hADSC senescence and osteoblastic differentiation ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000165879 ENSG00000168036 PMC5701012__F7 PD-L1 upregulation in response to DNA double-strand breaks ENSG00000149311 ENSG00000175054 ENSG00000115415 ENSG00000051180 ENSG00000125347 ENSG00000168610 ENSG00000139618 PMC2743272__F1 Mechanisms underlying the pleiotropic effects of statins in stroke ENSG00000070831 PMC6388629__F6 IPA network map depicting the DR signaling changes in HBEpCs after 6 h of infection with IAV H1N1 ENSG00000183735 ENSG00000102871 ENSG00000143839 ENSG00000171791 ENSG00000168040 ENSG00000148935 ENSG00000111348 ENSG00000197694 ENSG00000212916 PMC7006459__F1 Fyn activates divergent signaling cascades in effector lymphocytes ENSG00000213658 ENSG00000010810 PMC6388629__F5 Ingenuity Pathway Analysis (IPA) network map depicting the DR signaling changes in HBEpCs after 2 h of infection with IAV H1N1 ENSG00000106683 ENSG00000183735 ENSG00000102871 ENSG00000171791 ENSG00000111348 ENSG00000197694 ENSG00000028137 ENSG00000212916 PMC6962108__F1 Mechano-sensing by LSECs drives fibrotic processes ENSG00000114315 ENSG00000103335 PMC2588608__F2 Pathway Annotation and Summary Hit Table ENSG00000157766 PMC12229552__F9 Schematic diagram illustrating the mechanism by which DDX1 lysine methylation mediates MATR3 alternative splicing to regulate IVDD ENSG00000065833 ENSG00000214285 PMC4731263__F3 Mapping Proteome-Wide Interactions of Reactive Chemicals Using Chemoproteomic Platforms PMC10486522__F1 Leptin and a schematic representation of leptin-induced signaling pathways ENSG00000169047 ENSG00000198793 ENSG00000110931 ENSG00000168610 PMC10486522__F2 Adiponectin and a schematic representation of adiponectin-induced signaling pathways ENSG00000157500 ENSG00000169047 ENSG00000198793 ENSG00000136044 ENSG00000096717 ENSG00000168610 PMC3327653__F1 Recruiting a New Substrate for Triacylglycerol Synthesis in Plants: The Monoacylglycerol Acyltransferase Pathway ENSG00000173599 ENSG00000158669 ENSG00000198670 PMC6329310__F2 Role Of Atm In Ebv Life Cycle Regulation (A) The central role of ATM in the replication compartment of EBV ENSG00000149311 ENSG00000168283 ENSG00000136997 ENSG00000051180 ENSG00000185591 PMC6273696__F29 PI3K/Akt signaling pathway was regulated by vancomycin in HK-2 cells ENSG00000002330 ENSG00000105401 ENSG00000168036 PMC8198784__F3 Not Only Immune Escape—The Confusing Role of the TRP Metabolic Pathway in Carcinogenesis ENSG00000079432 ENSG00000162692 ENSG00000106546 PMC6273696__F27 G2/M DNA damage check point signaling pathway was regulated by vancomycin in HK-2 cells ENSG00000149311 ENSG00000175054 ENSG00000064393 ENSG00000087586 ENSG00000177519 ENSG00000149554 ENSG00000153827 ENSG00000276876 ENSG00000198625 PMC6273696__F28 Apoptosis signaling pathway was regulated by vancomycin in HK-2 cells ENSG00000067900 ENSG00000120868 ENSG00000148935 ENSG00000115760 ENSG00000084774 ENSG00000115317 ENSG00000026103 PMC8198784__F1 Not Only Immune Escape—The Confusing Role of the TRP Metabolic Pathway in Carcinogenesis ENSG00000262635 ENSG00000188676 PMC6484083__F2 The inferred and enriched PPI network from 43 genes that sensitize yeast to Mn when deleted ENSG00000079435 ENSG00000166169 PMC8198784__F5 Not Only Immune Escape—The Confusing Role of the TRP Metabolic Pathway in Carcinogenesis ENSG00000198793 ENSG00000168610 PMC6580320__F1 unctions and subsequent pathways of eukaryotic initiation factor 5A2 in human digestive system neoplasms ENSG00000163914 ENSG00000169710 ENSG00000163577 PMC3628365__F9 Speculative model of TERRA, hnRNP A1, and hTR/DNA-PKcs interactions at telomeres ENSG00000157106 PMC8939789__F7 Integrated model of potential mechanisms of HIV transcription and latency modulation by Beta-catenin ENSG00000168036 PMC8475157__F1 Abnormalities in the signaling pathway that exacerbate type I IFN responses ENSG00000213928 ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000140968 ENSG00000125347 ENSG00000276561 PMC11204236__F11 Proposed model illustrating the network of molecular mechanisms governed by miR-1 during early differentiation of the cardiac sinoatrial region ENSG00000285109 ENSG00000125686 ENSG00000143933 ENSG00000081189 ENSG00000089225 PMC6525084__F3 RNA-seq identifies synergistic (GxE) genes, which are enriched in NF-kB signaling pathway ENSG00000127191 PMC9662161__F5 Lycorine upregulates the expression of RMB10, promotes apoptosis and inhibits the proliferation and migration of cervical cancer cells ENSG00000170558 PMC10977403__F2 Dependence receptors have two properties: when the ligand is present, binding to the ligand promotes cell survival, migration or differentiation ENSG00000198793 ENSG00000177606 ENSG00000026103 PMC5383785__F5 Depiction of RAS-ERK signaling pathway and primary and secondary connections to substrates identified by time-resolved phosphoproteome profiling ENSG00000105722 ENSG00000047410 ENSG00000111581 ENSG00000284774 ENSG00000002330 ENSG00000124789 ENSG00000138798 ENSG00000130522 ENSG00000136111 ENSG00000169047 ENSG00000115904 ENSG00000141568 ENSG00000141564 ENSG00000067369 ENSG00000089159 ENSG00000038382 ENSG00000149269 ENSG00000163914 ENSG00000106070 ENSG00000136153 ENSG00000196498 ENSG00000136068 ENSG00000140262 ENSG00000095319 ENSG00000153201 ENSG00000126883 ENSG00000007866 ENSG00000168610 ENSG00000111596 ENSG00000080802 ENSG00000117036 ENSG00000143514 ENSG00000137166 ENSG00000100106 ENSG00000204120 ENSG00000146830 ENSG00000146648 ENSG00000100294 PMC4741654__F1 The complex metabolic network gearing the G1/S transition in leukemic stem cells: Hints to a rational use of antineoplastic agents ENSG00000228716 ENSG00000016391 PMC2395337__F1 5-Fuorouracil drug pathway demonstrating the interaction of multiple gene products ENSG00000228716 ENSG00000188641 ENSG00000128951 ENSG00000109320 ENSG00000136877 ENSG00000167325 ENSG00000161513 ENSG00000171848 ENSG00000147647 ENSG00000137563 ENSG00000167900 PMC5039188__F1 TLR signaling overview ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC7039202__F1 Modular composition of the SGOCP ENSG00000284320 ENSG00000228716 ENSG00000065911 ENSG00000100714 ENSG00000092621 ENSG00000164466 ENSG00000135069 ENSG00000146733 ENSG00000120254 ENSG00000116984 PMC7039202__F2 Sources of one-carbon units ENSG00000284320 ENSG00000065911 ENSG00000100714 ENSG00000262635 ENSG00000160282 ENSG00000084110 ENSG00000131480 ENSG00000183077 ENSG00000178445 ENSG00000159650 ENSG00000120254 PMC7039202__F3 Products of the SGOCP ENSG00000284320 ENSG00000228716 ENSG00000151224 ENSG00000065911 ENSG00000118520 ENSG00000123505 ENSG00000116649 ENSG00000102172 ENSG00000120254 ENSG00000133027 PMC8753976__F3 Signal transduction mechanism of exosomes in diabetic complications (Review) ENSG00000157557 PMC7039202__F4 Regulation of the SGOCP ENSG00000128272 ENSG00000144895 ENSG00000107077 PMC8753976__F4 Signal transduction mechanism of exosomes in diabetic complications (Review) ENSG00000136869 ENSG00000133961 PMC9103730__F1 Abiotic Stresses in Plants and Their Markers: A Practice View of Plant Stress Responses and Programmed Cell Death Mechanisms ENSG00000105722 PMC4005613__F1 Molecular Pathways: Co-Expression of Immune Checkpoint Molecules: Signaling Pathways and Implications for Cancer Immunotherapy ENSG00000089692 ENSG00000291603 ENSG00000117091 ENSG00000134982 ENSG00000163599 ENSG00000198793 PMC8200641__F2 Endoplasmic Reticulum Stress, a Target for Drug Design and Drug Resistance in Parasitosis ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC9661468__F4 Stress during mitosis activates apoptosis and inflammation ENSG00000164430 PMC8301761__F1 Molecular Landscape Influencing Prognoses of Epithelial Ovarian Cancer ENSG00000163464 ENSG00000019991 ENSG00000128052 PMC7051019__F2 a) Signaling pathways and transcription regulation of adipogenesis ENSG00000096717 ENSG00000283100 PMC8301761__F2 Molecular Landscape Influencing Prognoses of Epithelial Ovarian Cancer ENSG00000124102 ENSG00000109452 PMC8301761__F4 Molecular Landscape Influencing Prognoses of Epithelial Ovarian Cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000173273 PMC7802449__F4 Targeting TSH and IGF-1 Receptors to Treat Thyroid Eye Disease ENSG00000122882 ENSG00000165409 ENSG00000140443 PMC8249129__F8 Therapeutic Targets and Mechanism of Xingpi Jieyu Decoction in Depression: A Network Pharmacology Study ENSG00000291971 ENSG00000198793 ENSG00000136997 ENSG00000171791 PMC6378304__F5 Strategies to overcome NK resistance in solid tumors ENSG00000169245 ENSG00000186810 ENSG00000181847 ENSG00000163739 ENSG00000169429 ENSG00000231179 ENSG00000204520 ENSG00000146648 PMC5081350__F1 Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000173273 PMC6639976__F5 CXCL13 in prostate cancer PMC11206888__F7 Diagram of PI3K–AKT signaling pathway ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000069482 ENSG00000198793 ENSG00000169047 ENSG00000136997 ENSG00000104894 PMC5081350__F3 Wnt/Beta-catenin signaling therapeutic targets ENSG00000173273 PMC2737270__F1 Autophagy pathway and machinery.A ENSG00000152348 ENSG00000144848 ENSG00000120697 ENSG00000145782 ENSG00000182858 PMC5325695__F1 Emerging roles of p53 and other tumour-suppressor genes in immune regulation ENSG00000183735 ENSG00000213928 ENSG00000239732 ENSG00000187608 ENSG00000184995 ENSG00000115415 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 ENSG00000142166 ENSG00000026103 PMC8200641__F4 Endoplasmic Reticulum Stress, a Target for Drug Design and Drug Resistance in Parasitosis ENSG00000144895 PMC8219969__F1 Promising Future of Ferroptosis in Tumor Therapy ENSG00000168003 ENSG00000128272 ENSG00000151012 ENSG00000167468 ENSG00000072274 PMC1817784__F2 Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders ENSG00000198793 ENSG00000284161 PMC6861747__F17 Antidepressant-like effects and mechanisms of GXDSF via mediation of the CaMKII-CREB-BDNF signalling pathway in chronic unpredictable mild stress (CUMS)-induced depressive rats ENSG00000134363 PMC5462960__F7 Location of BHP biosynthetic genes and gene clusters in the genomes of SD1, SD3, and SD4 Acidobacteria and a number of selected environmental genomes as determined by BLAST protein searches ENSG00000110921 ENSG00000169291 ENSG00000113161 ENSG00000167508 PMC9381850__F7 Comprehensive Analysis of Interferon Regulatory Factor Expression: Correlation with Immune Cell Infiltration and Patient Prognosis in Endometrial Carcinoma ENSG00000112977 ENSG00000135960 ENSG00000168040 ENSG00000135517 PMC9300693__F7 Proposed mechanism by which thiostrepton modulates ferroptosis via the STAT3/GPX4 signalling pathway ENSG00000151012 ENSG00000167468 ENSG00000168610 PMC2935989__F3 GRK2 interactome involved in the modulation of cell cycle progression ENSG00000127445 ENSG00000123374 ENSG00000128602 PMC7588972__F1 Pivotal role of Mediator complex in the ABA signaling pathway ENSG00000104973 ENSG00000132964 ENSG00000284944 PMC2935989__F2 GRK2 interactome involved in cell migration ENSG00000291971 ENSG00000134982 ENSG00000006451 ENSG00000169047 ENSG00000117152 ENSG00000116741 ENSG00000136869 ENSG00000121966 ENSG00000164342 ENSG00000177425 PMC3102695__F5 Ciliary Neurotrophic Factor Induces Genes Associated with Inflammation and Gliosis in the Retina: A Gene Profiling Study of Flow-Sorted, Müller Cells ENSG00000132694 ENSG00000245848 ENSG00000127528 ENSG00000131095 ENSG00000168610 ENSG00000050426 ENSG00000108312 PMC7588972__F2 Simplified network of TFs and Mediator complex in regulating the abiotic stress responses ENSG00000175221 ENSG00000180182 ENSG00000104973 ENSG00000132964 PMC8973533__F5 Carbohydrate regulation response to cold during rhizome bud dormancy release in Polygonatum kingianum ENSG00000069482 ENSG00000082212 PMC11024860__F9 Working Model: HDAC6 maintains primordial follicle dormancy ENSG00000094631 PMC3791614__F1 The interactions between the control of the cell cycle and the expression of specific ligands for activating NK receptors in various pathologies ENSG00000175054 ENSG00000101146 ENSG00000135446 ENSG00000132646 ENSG00000123374 PMC9105874__F1 Fas/CD95 Signaling Pathway in Damage-Associated Molecular Pattern (DAMP)-Sensing Receptors ENSG00000278718 ENSG00000162711 ENSG00000092439 ENSG00000150782 ENSG00000137275 ENSG00000125538 ENSG00000166278 ENSG00000168040 ENSG00000168404 ENSG00000064012 ENSG00000285379 PMC9105874__F2 Fas/CD95 Signaling Pathway in Damage-Associated Molecular Pattern (DAMP)-Sensing Receptors ENSG00000278718 ENSG00000187688 ENSG00000150782 ENSG00000125538 ENSG00000124181 PMC6874533__F9 Silencing of long noncoding RNA HOXA11-AS inhibits the Wnt signaling pathway via the upregulation of HOXA11 and thereby inhibits the proliferation, invasion, and self-renewal of hepatocellular carcinoma stem cells ENSG00000005073 ENSG00000168036 ENSG00000140807 PMC3249073__F1 PtdEtn synthesis pathways in Plasmodium and yeast ENSG00000196549 PMC2666844__F3 In the absence of Wnt stimulation, the APC (adenomatous polyposis coli) forms a trimeric complex, known as the “destruction complex,” with glycogen synthase kinase-3B (GSK) and Axin ENSG00000134982 ENSG00000168036 ENSG00000168646 PMC2666844__F5 Simplified schematic of hepatocyte growth factor (HGF)/MET signaling pathway ENSG00000019991 PMC7693344__F1 Metabolic enzymes associated with glycolysis and the pentose phosphate pathway, depicted here, serve as critical regulators of inflammatory responses in myeloid and lymphoid cells ENSG00000198793 ENSG00000136997 PMC2666844__F6 Simplified schematic diagram of transforming growth factor-alpha/epidermal growth factor receptor signaling pathway (TGFA/EGFR) ENSG00000163235 ENSG00000146648 PMC8323674__F1 Research trends, hot spots and prospects for necroptosis in the field of neuroscience ENSG00000146215 ENSG00000136869 ENSG00000168404 ENSG00000164342 PMC12245917__F1 Molecular signal pathways related to H ENSG00000104856 ENSG00000165556 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000145365 ENSG00000168036 ENSG00000166670 ENSG00000127191 ENSG00000131023 ENSG00000164430 ENSG00000149968 ENSG00000157625 ENSG00000100985 ENSG00000175104 PMC12245917__F2 Crosstalk among H ENSG00000168036 PMC5802806__F5 Proposed mechanism ENSG00000167720 PMC6343143__F2 Proposed model of estrogen-induced ROS generation increase in thyrocyte ENSG00000086991 ENSG00000138385 PMC1782589__F2 Signalling cascades of the LPS pathway and reported sites of IL-10 intervention ENSG00000162889 ENSG00000170458 PMC11635231__F2 Importance of FXR in the enterohepatic circulation of BAs ENSG00000138075 ENSG00000160867 ENSG00000276559 ENSG00000167910 ENSG00000180432 ENSG00000115271 ENSG00000143921 ENSG00000135929 PMC11635231__F3 FXR in four lung diseases ENSG00000150782 ENSG00000124216 ENSG00000181019 ENSG00000138798 ENSG00000152213 ENSG00000019549 ENSG00000168610 ENSG00000146648 PMC7082402__F1 Red blood cell—inflammation vicious circle in sickle cell disease ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC9552847__F7 PTEN loss promotes Warburg effect and prostate cancer cell growth by inducing FBP1 degradation ENSG00000145604 PMC3248767__F2 Bevacizumab Treatment for Advanced Breast Cancer ENSG00000019991 ENSG00000163235 ENSG00000138798 PMC11577950__F7 Metabolic pathway diagram of lysosome and autophagy pathways of DEGs after knockdown of HlDnmt1 and HlDnmt in Haemaphysalis longicornis ENSG00000261832 ENSG00000198951 ENSG00000107798 ENSG00000181523 ENSG00000213614 ENSG00000134575 ENSG00000196743 ENSG00000150967 ENSG00000102575 ENSG00000038002 ENSG00000169919 ENSG00000107331 ENSG00000291507 ENSG00000127415 ENSG00000189067 PMC2888475__F1 Cellular apoptosis pathways and intervention by both cellular anti-apoptotic proteins and viral proteins encoded by oncolytic Ad, HSV and VV ENSG00000132906 ENSG00000171791 ENSG00000168040 PMC9380140__F7 Upregulation of RCAN1.4 by HIF1A alleviates OGD‐induced inflammatory response in astrocytes ENSG00000150782 PMC8213017__F1 Modulation of Ferroptosis and Its Role in Central Nervous System Diseases ENSG00000168003 ENSG00000151012 ENSG00000196839 ENSG00000167468 ENSG00000197429 ENSG00000111684 PMC3401974__F2 Mammalian target of rapamycin (mTOR) pathway regulates T-cell activation, differentiation and migration ENSG00000134982 ENSG00000198793 ENSG00000126353 PMC11726960__F2 Key characteristics of models used to recreate cardiac systems in vitro and relevant signaling pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000138606 PMC3055312__F1 Signaling pathways regulating GSK3 and functions of GSK3 related to mood regulation ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC6713350__F5 Bigenic mouse model of FSGS reveals perturbed pathways in podocytes, mesangial cells and endothelial cells ENSG00000167601 ENSG00000107562 ENSG00000130158 ENSG00000181104 ENSG00000149782 ENSG00000213626 ENSG00000087303 ENSG00000174807 ENSG00000059758 ENSG00000278788 ENSG00000143537 ENSG00000019582 ENSG00000041982 ENSG00000159674 ENSG00000167941 ENSG00000019549 ENSG00000196182 ENSG00000111341 ENSG00000105810 ENSG00000291918 ENSG00000168404 ENSG00000118257 ENSG00000134200 ENSG00000164342 PMC10484938__F7 Metabolic remodeling in the brain and liver following STF ENSG00000086205 ENSG00000166532 ENSG00000177181 ENSG00000122966 ENSG00000166123 ENSG00000116984 PMC6182269__F1 Cell intrinsic dysregulation of innate immune signaling in MDS HSCs ENSG00000162711 ENSG00000150782 ENSG00000255833 ENSG00000170458 ENSG00000125538 ENSG00000173039 ENSG00000134070 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000115594 PMC8074054__F1 Sarcopenia and Vitamin D Deficiency in Patients with Crohn’s Disease: Pathological Conditions That Should Be Linked Together PMC6460856__F3 MyD88 played a critical role in alveolar macrophage-mediated inflammatory response to CNTs ENSG00000125538 ENSG00000172936 ENSG00000175104 PMC4570544__F1 The Clp proteases and chaperones in Plasmodium and the Plasmodium translocon of exported proteins ENSG00000198894 ENSG00000125656 PMC5876639__F2 Cellular senescence pathway activated by NPM-ALK ENSG00000135446 ENSG00000105810 ENSG00000168610 PMC11890630__F8 Progressive accumulation of transcriptional alterations during the progression of T2D reduces adipocyte thermogenic capacity ENSG00000162711 ENSG00000118729 ENSG00000172572 ENSG00000173039 ENSG00000109819 ENSG00000111875 ENSG00000175115 ENSG00000198838 ENSG00000196218 ENSG00000132326 ENSG00000151617 ENSG00000096717 ENSG00000163517 PMC5187684__F1 A schematic of metabolic intermediate labeling from 13C glutamine ENSG00000112992 PMC8240065__F4 Responses of Mast Cells to Pathogens: Beneficial and Detrimental Roles ENSG00000108691 ENSG00000081041 ENSG00000117091 ENSG00000125538 ENSG00000203710 ENSG00000108688 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 ENSG00000117322 PMC6460856__F2 Mechanisms by which carbon-based nanoparticles induce cytotoxicity of macrophages ENSG00000162711 PMC9710325__F2 Perspectives on Challenges in Cannabis Drug Delivery Systems: Where Are We? ENSG00000128272 ENSG00000002330 ENSG00000101255 ENSG00000291971 PMC8340019__F4 Jasmonates, Calcium, and Glutathione in Plants to Combat Abiotic Stresses Through Precise Signaling Cascade ENSG00000105722 ENSG00000136997 ENSG00000141639 PMC10977574__F8 Compound-key target-core pathway ENSG00000087245 ENSG00000140564 ENSG00000157764 ENSG00000197635 ENSG00000123572 ENSG00000143839 ENSG00000087085 ENSG00000112715 ENSG00000105639 ENSG00000064300 ENSG00000010671 ENSG00000121966 ENSG00000103811 ENSG00000149311 ENSG00000117020 ENSG00000109861 ENSG00000082175 ENSG00000163394 ENSG00000134853 ENSG00000037280 ENSG00000151617 ENSG00000196689 PMC2868837__F3 Major gene products affected by virulent infection ENSG00000115602 ENSG00000115008 ENSG00000125538 ENSG00000177606 ENSG00000122877 ENSG00000112715 ENSG00000073756 ENSG00000146648 ENSG00000150630 PMC7281398__F5 Summary of Gene Ontology Analysis and Pathway analysis on genes that are associated with ex vivo VP16 response, ranked according to adjusted p-values ENSG00000072571 ENSG00000115163 ENSG00000122952 ENSG00000132646 ENSG00000112578 ENSG00000175643 ENSG00000146410 ENSG00000177084 ENSG00000136108 ENSG00000112312 PMC7409324__F2 NFkB-induced expression of MHC-I ENSG00000104856 ENSG00000173039 ENSG00000175104 ENSG00000127191 PMC10977574__F9 Core-compound-core key target-core pathway ENSG00000087245 ENSG00000100906 ENSG00000291971 ENSG00000198793 ENSG00000113161 ENSG00000171791 ENSG00000121879 ENSG00000073756 ENSG00000132170 ENSG00000179295 ENSG00000180210 ENSG00000149968 ENSG00000128052 ENSG00000164362 ENSG00000123374 ENSG00000100985 ENSG00000146648 PMC6357155__F2 The life cycle of SARS-CoV and MERS-CoV in host cells ENSG00000197635 ENSG00000130234 PMC7409324__F3 Interferon (IFN)-induced expression of MHC-I ENSG00000159128 ENSG00000111537 ENSG00000105397 ENSG00000027697 ENSG00000125347 ENSG00000168610 ENSG00000142166 PMC7409324__F4 Therapeutic interference to boost MHC-I antigen presentation of tumors ENSG00000213928 ENSG00000173039 ENSG00000125347 ENSG00000196396 ENSG00000168610 ENSG00000179295 ENSG00000127445 ENSG00000111537 ENSG00000115415 ENSG00000078747 ENSG00000198742 ENSG00000121481 ENSG00000102921 ENSG00000083799 ENSG00000146648 PMC8517994__F2 MiRNAs during Endoplasmic Reticulum Stress Induced Apoptosis in Digestive Cancer ENSG00000144895 ENSG00000100219 ENSG00000181652 ENSG00000026103 PMC10938947__F2 Introduction of pathways related to bone regeneration, like WNT signaling pathway ENSG00000178860 ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC7555571__F1 AHR signaling pathway ENSG00000110711 ENSG00000291971 ENSG00000106546 PMC8651533__F2 Proline metabolism and redox; maintaining a balance in health and disease ENSG00000059573 ENSG00000100033 PMC9199231__F1 Interplay between noncoding RNA and YAP/TAZ signaling in cancers: molecular functions and mechanisms ENSG00000129474 ENSG00000087095 ENSG00000144560 ENSG00000163914 ENSG00000136518 PMC10938947__F3 Introduction of pathways related to bone regeneration, like Hedgehog signaling pathway, Notch signaling pathway and FGF signaling pathway ENSG00000178860 ENSG00000128917 ENSG00000184916 ENSG00000128602 ENSG00000163501 ENSG00000090932 PMC10938947__F4 Introduction of pathways related to bone regeneration, like BMP/TGFBsignaling pathway ENSG00000178860 ENSG00000170365 ENSG00000137834 PMC5816931__F2 Recognition of Mycobacterium tuberculosis (Mtb) by Dectin-1 ENSG00000187796 ENSG00000134982 PMC7291661__F2 Proinflammatory cytokines regulating keratinocytes or stem cells ENSG00000168036 ENSG00000168610 ENSG00000076604 PMC10977574__F7 Core pathway of AP intervened by SHG (PI3K-Akt signaling pathway) ENSG00000002330 ENSG00000169047 PMC4377297__F1 The role of trophoblastic microRNAs in placental viral infection ENSG00000113360 ENSG00000123908 PMC7465511__F2 MPN: The Molecular Drivers of Disease Initiation, Progression and Transformation and their Effect on Treatment ENSG00000151376 ENSG00000163930 ENSG00000198793 ENSG00000124766 ENSG00000171791 ENSG00000187266 ENSG00000008083 ENSG00000102145 ENSG00000141867 ENSG00000159216 ENSG00000169249 ENSG00000117400 ENSG00000143995 PMC8277214__F1 Characterizing a Common CERS2 Polymorphism in a Mouse Model of Metabolic Disease and in Subjects from the Utah CAD Study ENSG00000139624 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000119537 ENSG00000143418 PMC6742404__F1 Ontogenetic expression of thyroid hormone signaling genes: An in vitro and in vivo species comparison ENSG00000119138 ENSG00000197971 ENSG00000086730 PMC5696170__F7 Measurements of heterotypic associations between cluster of differentiation CD74 and CD44 in human breast cancer-derived cells ENSG00000019582 ENSG00000173039 ENSG00000026508 PMC7528551__F2 Phosphatidylcholines constitute a major metabolic signature of VAT versus SAT ENSG00000110721 ENSG00000018510 ENSG00000111666 ENSG00000134255 ENSG00000133027 PMC6949682__F5 Canonical pathway; (b) heat map of the genes related to the colitis signaling pathway in colonic epithelial cells obtained from wild-type (WT) and Slc5a8-null (KO) mice fed the fiber-free diet (FF-diet) ENSG00000164220 ENSG00000184194 ENSG00000187569 ENSG00000113600 ENSG00000147437 ENSG00000198851 ENSG00000146469 ENSG00000136854 ENSG00000203857 ENSG00000007171 ENSG00000123999 ENSG00000224320 ENSG00000139372 ENSG00000073861 ENSG00000112299 ENSG00000116014 PMC3636710__F9 LBP/CD14-independent activation of host cells by E·albumin ENSG00000170458 ENSG00000136869 PMC7547598__F6 Transcriptome analysis reveals potential immune function-related regulatory genes/pathways of female Lubo goat submandibular glands at different developmental stages ENSG00000232326 ENSG00000105656 ENSG00000129355 ENSG00000158869 ENSG00000174564 ENSG00000141968 ENSG00000121966 ENSG00000106683 ENSG00000041982 ENSG00000186340 ENSG00000213658 ENSG00000136997 ENSG00000177084 ENSG00000166349 ENSG00000132109 ENSG00000259207 ENSG00000128594 ENSG00000152495 ENSG00000119535 ENSG00000110448 ENSG00000081237 ENSG00000197471 ENSG00000105251 ENSG00000101057 ENSG00000107447 ENSG00000175097 ENSG00000105122 ENSG00000078053 ENSG00000105287 PMC7547598__F8 Transcriptome analysis reveals potential immune function-related regulatory genes/pathways of female Lubo goat submandibular glands at different developmental stages ENSG00000291603 ENSG00000110395 ENSG00000213658 ENSG00000117091 ENSG00000010810 ENSG00000135446 ENSG00000163599 ENSG00000113520 ENSG00000113263 PMC10816220__F1 Transforming growth factor B (TGFB) and bone morphogenetic proteins (BMP) signaling pathway ENSG00000170365 ENSG00000137834 ENSG00000198793 PMC6769118__F9 Anti-autophagic and anti-apoptotic pathway activated in human DCs by P ENSG00000174125 ENSG00000177169 PMC7090203__F3 Physical activity alters circulating monocyte features and obese adipose tissue macrophage distinction ENSG00000108691 ENSG00000111537 ENSG00000170458 ENSG00000115415 ENSG00000137265 ENSG00000136869 ENSG00000121807 ENSG00000136826 PMC7090203__F2 LPS transferring pathway and modulation of TLR4 signaling cascade ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC6704489__F3 Gene category of the NFKB signaling pathway ENSG00000132109 ENSG00000242689 ENSG00000102871 ENSG00000109654 ENSG00000111321 ENSG00000150455 ENSG00000127191 ENSG00000010671 ENSG00000095585 ENSG00000149311 ENSG00000100290 ENSG00000226275 ENSG00000213658 ENSG00000170458 ENSG00000186716 ENSG00000125538 ENSG00000131323 ENSG00000124181 ENSG00000175104 ENSG00000135517 PMC3671299__F2 Schematic diagram of AB accumulation mechanism ENSG00000144895 ENSG00000087085 ENSG00000141052 ENSG00000198911 PMC5424863__F2 Pathway hyperactivation defined by alterations of the PI3K/AKT/mTOR pathway PMC3887202__F1 De novo synthesis of steroids, oxysterols, and bile acids from cholesterol ENSG00000180432 ENSG00000179142 ENSG00000135929 PMC6713396__F4 Transcriptional blood signatures for active and amphotericin B treated visceral leishmaniasis in India ENSG00000147162 ENSG00000175745 ENSG00000140505 ENSG00000285246 ENSG00000131910 ENSG00000196712 ENSG00000106546 ENSG00000026103 PMC9274491__F8 RASAL2 mediated the enhancement of YAP1/TIAM1 signaling promotes malignant phenotypes of pancreatic ductal adenocarcinoma ENSG00000156299 PMC3903278__F8 Cofilin regulating actin dynamics and initiating HSV-1 entry ENSG00000106683 ENSG00000163914 ENSG00000067900 ENSG00000146648 PMC8067275__F1 MicroRNAs that regulate the core components of Hippo signaling pathway ENSG00000186575 ENSG00000109321 ENSG00000144560 ENSG00000150457 ENSG00000131023 PMC5115734__F1 Evolution of the Tetrapyrrole Biosynthetic Pathway in Secondary Algae: Conservation, Redundancy and Replacement ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000188690 PMC3576027__F2 Activity-dependent neuronal signalling and autism spectrum disorder ENSG00000198793 ENSG00000198576 PMC3576027__F3 Activity-dependent neuronal signalling and autism spectrum disorder ENSG00000174576 ENSG00000138380 ENSG00000198576 PMC3561559__F9 Schematic model of autoregulation of BMI1 ENSG00000168283 ENSG00000134982 ENSG00000168036 PMC2684140__F9 Schematic representation of the S ENSG00000130234 ENSG00000291442 PMC8811422__F19 Chinese Herbal Formula Ruyan Neixiao Cream Inhibits Angiogenesis of Precancerous Breast Lesions via Regulation of Ras/Raf/MEK/ERK Signaling Pathway ENSG00000100234 PMC4238427__F4 Ingenuity pathway analysis of top differentially affected pathways from the microarray data ENSG00000127528 ENSG00000109654 ENSG00000197045 ENSG00000165219 PMC5925761__F1 One-carbon metabolism (1-CM) and pentose phosphate pathway (PPP) at the cross-road between anabolism and redox balance ENSG00000065911 ENSG00000128272 ENSG00000092621 ENSG00000136997 ENSG00000078237 ENSG00000146733 PMC6780043__F4 Effects of nanomaterials (NMs) on Ca2+ channels located on the cell membrane and Ca2+ stores and subsequent dysfunction of ion homeostasis ENSG00000167323 ENSG00000198793 PMC6894260__F1 Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC8160634__F4 Potential Role for HUWE1 in Modulating Cisplatin Sensitivity ENSG00000149311 ENSG00000196591 ENSG00000086758 PMC10610204__F4 Activation of DNA damage-induced checkpoint signaling pathway in ATM-deficient cells and mechanism of ATR inhibitor and ATM defect-induced synthesis and lethality (by Figdraw) ENSG00000149311 ENSG00000175054 ENSG00000164053 PMC10610204__F5 WEE1 and TP53 synthetic lethal interaction mechanism (by Figdraw) ENSG00000149311 ENSG00000175054 ENSG00000123374 ENSG00000138385 PMC7148120__F3 Microglial activation on metabolism ENSG00000168329 ENSG00000111537 PMC5735682__F9 Hypothetical illustration for the role of CWP ENSG00000134982 ENSG00000168036 PMC8160634__F2 Potential Role for HUWE1 in Modulating Cisplatin Sensitivity ENSG00000175054 ENSG00000094804 ENSG00000086758 PMC5821468__F5 Severe congenital neutropenias ENSG00000141349 ENSG00000171135 ENSG00000162676 ENSG00000004455 ENSG00000015285 ENSG00000132842 ENSG00000179348 ENSG00000143669 ENSG00000132549 ENSG00000121966 PMC8712645__F1 Function and Molecular Mechanism of the DNA Damage Response in Immunity and Cancer Immunotherapy ENSG00000012048 ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000187796 ENSG00000163565 PMC8712645__F4 Function and Molecular Mechanism of the DNA Damage Response in Immunity and Cancer Immunotherapy ENSG00000164430 ENSG00000163599 PMC5450843__F10 A model for transcriptional regulation of RGC differentiation ENSG00000119614 ENSG00000016082 PMC4097318__F1A Mechanisms of Liver Injury in Non-Alcoholic Steatohepatitis ENSG00000108691 ENSG00000100344 PMC3079800__F1 Parenteral Nutrition Impairs Lymphotoxin B Receptor Signaling via NF- KB ENSG00000104856 ENSG00000099866 ENSG00000131142 ENSG00000111321 ENSG00000115009 PMC9105027__F1 Regulatory Mechanisms of Prg4 and Gdf5 Expression in Articular Cartilage and Functions in Osteoarthritis ENSG00000163235 ENSG00000113070 ENSG00000116690 ENSG00000146648 PMC9105027__F2 Regulatory Mechanisms of Prg4 and Gdf5 Expression in Articular Cartilage and Functions in Osteoarthritis ENSG00000154736 ENSG00000281324 ENSG00000162337 ENSG00000149968 ENSG00000134982 ENSG00000168036 ENSG00000116690 ENSG00000100985 ENSG00000158859 PMC5655361__F2 Signaling networks in aging ENSG00000129347 ENSG00000118515 PMC3072066__F5 Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state ENSG00000125820 ENSG00000205927 ENSG00000164690 PMC3294166__F8 KEGG pathway mapping overlay for acidic pHe upregulated genes pertinent to OXPHOS ENSG00000090402 PMC2254485__F5 Tumour growth and metastasis: Role of NPP2-catalyzed reactions ENSG00000168036 ENSG00000198670 ENSG00000125084 PMC9612825__F1 Metabolic network ENSG00000125166 ENSG00000065833 ENSG00000197713 ENSG00000291507 ENSG00000122966 ENSG00000172005 ENSG00000087842 ENSG00000146701 ENSG00000062485 ENSG00000167701 PMC8308226__F1 MiR-155 in Nutrition: Modulating Cancer-Associated Inflammation ENSG00000134086 ENSG00000168610 PMC5354660__F5 Cycling hypoxia affects cell invasion and proliferation through regulation of claudins ENSG00000228716 ENSG00000101945 ENSG00000135446 ENSG00000105810 PMC7796621__F7 Schematic model of the anti-inflammatory effects of hMuSCs on DSS-induced IBD ENSG00000106546 PMC7555602__F3 Impact of redox imbalance on canonical pathway of miRNAs biogenesis ENSG00000113360 ENSG00000132341 PMC3901115__F2 Autophagy pathway: Molecular features ENSG00000110497 ENSG00000198793 ENSG00000145782 PMC2410042__F2 Diasporin Pathway: a tumor progression-related transcriptional network that predicts breast cancer survival ENSG00000182578 ENSG00000141867 ENSG00000003436 ENSG00000160208 ENSG00000164530 ENSG00000105329 ENSG00000213445 ENSG00000184371 ENSG00000265972 ENSG00000164105 PMC3784161__F1 AKT-mammalian target of rapapmycin (mTOR) signalling pathway ENSG00000291971 ENSG00000150907 ENSG00000169047 PMC3784161__F2 AKT controls T-cell differentiation ENSG00000134982 ENSG00000198793 ENSG00000164327 PMC4735774__F9 Schematic working model for presumed mechanisms underlying the effects of Mus81 knockdown on hepatocellular carcinoma (HCC) cells in response to chemotherapeutic drugs ENSG00000123374 PMC9139752__F1 Can Schlafen 11 Help to Stratify Ovarian Cancer Patients Treated with DNA-Damaging Agents? ENSG00000175054 ENSG00000172716 PMC7584116__F2 T cell metabolism by SOCE and Ca2+ signaling ENSG00000059804 ENSG00000152495 ENSG00000167323 ENSG00000293604 ENSG00000136997 ENSG00000137265 ENSG00000110931 ENSG00000096088 ENSG00000110218 ENSG00000159399 ENSG00000109689 PMC6461560__F4 Phosphosites identified in proteins of the RAS-RAF-MAPK and PI3K-AKT-mTOR signaling pathway in H3255 (left panel) and H1975 (right panel) ENSG00000138798 ENSG00000198793 ENSG00000164327 ENSG00000108443 ENSG00000141564 PMC7584116__F1 Ca2+ regulates metabolic pathways at different stages of the T cell life cycle ENSG00000134982 ENSG00000110931 ENSG00000110218 PMC9206313__F2 RCAN1-mediated calcineurin inhibition as a target for cancer therapy ENSG00000169618 ENSG00000159200 ENSG00000050344 ENSG00000111837 ENSG00000145321 ENSG00000169429 ENSG00000112715 ENSG00000140443 PMC9095921__F1 Targeting C–C Chemokine Receptor 5: Key to Opening the Neurorehabilitation Window After Ischemic Stroke ENSG00000159224 ENSG00000163914 PMC1526532__F1 Genomic Analysis of the Opi− Phenotype ENSG00000196549 ENSG00000146005 ENSG00000173599 PMC8423581__F3 Exosome: Function and Application in Inflammatory Bone Diseases ENSG00000291971 ENSG00000082512 ENSG00000175104 ENSG00000127191 PMC8423581__F4 Exosome: Function and Application in Inflammatory Bone Diseases ENSG00000128272 ENSG00000281324 ENSG00000162337 ENSG00000134569 ENSG00000134982 ENSG00000167941 PMC10750275__F1 YAP Signaling in Regulation of Programmed Cell Death and Drug Resistance in Cancer ENSG00000186575 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC6590390__F1 Wnt, Beta-catenin. and PCP signaling ENSG00000134982 ENSG00000177606 ENSG00000168036 PMC4057899__F8 Schematic diagram ENSG00000138798 ENSG00000125538 ENSG00000146648 PMC5143481__F2 TLR4 signaling mechanisms ENSG00000170458 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC8423581__F2 Exosome: Function and Application in Inflammatory Bone Diseases ENSG00000104856 ENSG00000173039 ENSG00000172936 ENSG00000175104 PMC5903700__F6 Schematic diagram summarising the biological processes underlying the association of the 35‐gene expression signature with PTEN/AKT signalling pathways ENSG00000198793 ENSG00000133112 ENSG00000163017 PMC9039621__F1 Complement-Mediated Neutralisation Identified in Ebola Virus Disease Survivor Plasma: Implications for Protection and Pathogenesis ENSG00000039537 ENSG00000085265 ENSG00000062485 ENSG00000236625 PMC9189314__F2 Inflammasomes and Pyroptosis of Liver Cells in Liver Fibrosis ENSG00000278718 ENSG00000125538 ENSG00000265972 PMC10137108__F1 Contribution of various long non-coding RNAs and microRNAs in osteogenic pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198742 ENSG00000168036 PMC10137108__F2 Bone formation by miRNAs ENSG00000167941 PMC11602477__F1 Wnt/Beta-catenin pathway in CSCs ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC10137108__F3 Long non-coding RNA that regulates osteosarcoma invasion and metastasis PMC11602477__F2 Notch signaling pathway in CSCs (By Figdraw) ENSG00000148400 ENSG00000074181 PMC11602477__F3 Hedgehog signaling pathway in CSCs ENSG00000164690 ENSG00000128602 PMC6345911__F7 Postulated mechanism for ceramide dependent regulation of G-CSF signaling in BMCs ENSG00000081041 ENSG00000168610 ENSG00000143418 PMC10750275__F7 YAP Signaling in Regulation of Programmed Cell Death and Drug Resistance in Cancer ENSG00000136603 ENSG00000189403 ENSG00000057663 PMC10151765__F2 Generation, activation, and polarization of monocyte-derived macrophages in human malignancies ENSG00000143799 ENSG00000010810 ENSG00000168040 ENSG00000026103 PMC6330281__F2 Wnt signaling cascades ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000168036 PMC4248054__F1 Mechanism of oestrogen action ENSG00000291971 ENSG00000113070 ENSG00000146648 PMC7015151__F1 Outline of T-cell development and T-cell gene regulatory network ENSG00000157554 ENSG00000166349 ENSG00000157404 ENSG00000138795 ENSG00000140262 ENSG00000078399 ENSG00000175097 ENSG00000081189 ENSG00000104903 ENSG00000159216 ENSG00000162676 ENSG00000066336 ENSG00000135363 ENSG00000107485 ENSG00000152804 ENSG00000165702 ENSG00000114315 ENSG00000143995 PMC3062054__F4 Roles for Growth Factors in Cancer Progression ENSG00000157404 ENSG00000186716 ENSG00000146648 PMC3062054__F2 Roles for Growth Factors in Cancer Progression ENSG00000105722 ENSG00000137834 ENSG00000002330 ENSG00000136997 PMC8075259__F2 Anaplasmataceae: Dichotomous Autophagic Interplay for Infection ENSG00000126775 ENSG00000120705 ENSG00000284099 ENSG00000112561 ENSG00000057663 PMC8396570__F1 Putative Role of Vitamin D for COVID-19 Vaccination ENSG00000162711 ENSG00000183735 ENSG00000108691 ENSG00000239732 ENSG00000108688 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC8134850__F7 Saponins from Panax japonicus ameliorate age-related renal fibrosis by inhibition of inflammation mediated by NFKB and TGFB1/Smad signaling and suppression of oxidative stress via activation of Nrf2-ARE signaling ENSG00000087245 ENSG00000181019 ENSG00000100985 ENSG00000079999 PMC3556981__F5 Analysis of Central Metabolic Pathway Gene Expression with Compartmentalization Information.Heat maps in boxes indicate the expression of individual genes, and the chart plots indicate the aggregate expression levels of the pathway genes ENSG00000062485 PMC9254496__F1 Crystal structure of mevalonate 3,5-bisphosphate decarboxylase reveals insight into the evolution of decarboxylases in the mevalonate metabolic pathways ENSG00000110921 ENSG00000197429 ENSG00000198947 PMC3767923__F6 Schematic of DNA damage response to double strand breaks ENSG00000149311 ENSG00000079246 ENSG00000039650 ENSG00000187736 ENSG00000253729 PMC8398289__F3 Elucidation of Melanogenesis-Associated Signaling Pathways Regulated by Argan Press Cake in B16 Melanoma Cells ENSG00000070961 ENSG00000168036 ENSG00000080166 ENSG00000139625 PMC3177306__F2 The canonical vertebrate Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000064393 ENSG00000168036 PMC1774601__F2 Death receptor mediated (extrinsic) pathway of apoptosis ENSG00000102871 ENSG00000168040 ENSG00000026103 PMC6036444__F1 Schematic of one-carbon metabolism ENSG00000284320 ENSG00000228716 ENSG00000065911 ENSG00000100714 ENSG00000145020 ENSG00000120254 PMC2970711__F7 Scheme of cross-talk interactions between TIM-3, Gal-9 and TLR4 signaling networks ENSG00000107562 ENSG00000163739 ENSG00000125538 ENSG00000136869 PMC9157498__F2 Noncanonical PD-1/PD-L1 Axis in Relation to the Efficacy of Anti-PD Therapy ENSG00000115415 PMC7419046__F2 TGF‐B signaling regulates lncRNA expression and mechanisms of TGF‐B signaling control by lncRNAs ENSG00000253352 PMC5450629__F8 Tumor microenvironment underlies acquired resistance to CSF1R inhibition in gliomas ENSG00000113520 ENSG00000140443 PMC4063317__F5 Receptors and cellular signaling pathways implicated in the antitumor effect of ANP ENSG00000168036 ENSG00000168610 ENSG00000145244 PMC4227274__F9 Cellular defense mechanisms induced by IPNV infection in CHSE-214 cells ENSG00000002330 ENSG00000115415 ENSG00000164342 PMC6245951__F7 Attenuating Effects of 1,2,3,4,6 Penta-O-Galloyl-Beta-D-Glucose on Pro-Inflammatory Responses of LPS/IFNGamma-activated BV-2 Microglial Cells through NFƙB and MAPK Signaling Pathways ENSG00000169291 ENSG00000070831 ENSG00000170458 ENSG00000156299 ENSG00000172936 ENSG00000136869 ENSG00000113263 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC11545288__F6 PPI network analysis of core targets screened from potential targets (A) and network diagram of the active component–key target pathway (B) of sugarcane vinegar polyphenols to mitigate oxidative stress ENSG00000116044 ENSG00000173039 ENSG00000123374 ENSG00000100985 ENSG00000073756 ENSG00000168610 PMC11545288__F7 Mechanistic Insights into the Antioxidant Potential of Sugarcane Vinegar Polyphenols: A Combined Approach of DPPH-UPLC-MS, Network Pharmacology and Molecular Docking ENSG00000148346 ENSG00000108691 ENSG00000163220 ENSG00000073910 ENSG00000131323 ENSG00000155313 ENSG00000167182 ENSG00000143556 ENSG00000115009 PMC7568159__F2 MyD88 and IRAK-4-mediated signaling pathway ENSG00000174123 ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC3099592__F2 Activation of mast cells initiates a cascade of events resulting in Th2 polarization and both positive and negative feedback regulatory loops ENSG00000105639 PMC5342987__F1 BMP4 cellular signaling pathway including activators and inhibitors ENSG00000095739 ENSG00000198742 PMC3073545__F2 Endocannabinoids in Liver Disease ENSG00000042832 ENSG00000026103 PMC4989048__F3 PhenomeExpress analysis ENSG00000185513 ENSG00000215440 ENSG00000128641 ENSG00000169071 ENSG00000145681 ENSG00000168702 ENSG00000130294 ENSG00000123728 ENSG00000181894 ENSG00000166619 ENSG00000132361 ENSG00000112118 ENSG00000140092 ENSG00000162772 ENSG00000055955 ENSG00000136247 ENSG00000168961 ENSG00000157240 ENSG00000145431 ENSG00000125398 ENSG00000038427 ENSG00000006327 ENSG00000108821 ENSG00000078098 ENSG00000177575 ENSG00000164761 ENSG00000131747 ENSG00000070731 ENSG00000100526 ENSG00000186827 ENSG00000139219 ENSG00000105397 ENSG00000122952 ENSG00000156970 ENSG00000143507 ENSG00000026508 ENSG00000115361 ENSG00000138180 ENSG00000115009 ENSG00000116977 ENSG00000156273 ENSG00000152661 ENSG00000149084 ENSG00000196154 ENSG00000119681 ENSG00000104368 ENSG00000157557 ENSG00000105664 ENSG00000011422 ENSG00000178573 ENSG00000167779 ENSG00000056558 ENSG00000113140 ENSG00000173530 ENSG00000185386 ENSG00000171812 ENSG00000146263 ENSG00000049089 PMC11011352__F1 Regulating Protein–RNA Interactions: Advances in Targeting the LIN28/Let-7 Pathway ENSG00000131914 ENSG00000187772 ENSG00000134744 ENSG00000128191 ENSG00000113360 PMC2912804__F7 Role of PGE2 in bridging TLR4 signaling and intestinal tumorigenesis ENSG00000136869 ENSG00000146648 PMC6189293__F1 Complex interplay between O-GlcNAcylation and PI3K/AKT/mTOR signaling pathway controls numerous biological processes ENSG00000147162 ENSG00000198793 PMC6189293__F2 O-GlcNAcylation and PI3K/AKT/mTOR signaling pathway cross-dysregulation in human chronic diseases ENSG00000087245 ENSG00000002330 ENSG00000150907 ENSG00000169047 ENSG00000198793 ENSG00000100985 PMC3583082__F3 This diagram summarizes the signaling pathway in thyroid carcinomas ENSG00000157764 ENSG00000198793 ENSG00000168036 PMC3632399__F5 RAS oncogene signaling ENSG00000087245 ENSG00000177606 ENSG00000185591 ENSG00000100985 ENSG00000112715 ENSG00000167182 PMC4048454__F5 Metabolic pathway of vancomycin biosynthesis ENSG00000122966 PMC8969440__F7 Cordyceps militaris Modulates Intestinal Barrier Function and Gut Microbiota in a Pig Model ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC9454096__F1 Evasion of interferon-mediated immune response by arteriviruses ENSG00000088888 ENSG00000187608 ENSG00000185591 ENSG00000167182 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC4248746__F10 Model depicting the molecular mechanism involved in counterregulation of TLR-induced inflammatory signature by dectin-1 ENSG00000033800 ENSG00000168036 ENSG00000172936 ENSG00000184216 PMC3457991__F3 Systematic Analysis of microRNA Targeting Impacted by Small Insertions and Deletions in Human Genome ENSG00000132906 ENSG00000002330 ENSG00000138798 ENSG00000115419 ENSG00000139618 PMC7757045__F4 LncRNA Regulates HCC Invasion and Progression by Modulating Tumor Immune Escape ENSG00000099860 ENSG00000146648 PMC8224460__F1 Resistance Responses of Potato Plants to Potato Virus Y Are Associated with an Increased Cellular Methionine Content and an Altered SAM:SAH Methylation Index ENSG00000110395 PMC12107760__F9 Changes in the main metabolic pathways of wheat root system in response to Act12 inoculation under drought stress ENSG00000171759 ENSG00000173868 PMC8933007__F4 Nicotinamide n-methyltransferase (NNMT) links nicotinamide adenine dinucleotide (NAD) and methionine metabolism during replicative senescence ENSG00000105835 ENSG00000173614 ENSG00000116984 PMC10960729__F6 Activation of cGAS–STING signaling pathway in autoimmune diseases, neurological diseases, and visceral inflammations ENSG00000149311 ENSG00000105612 ENSG00000147894 PMC4066639__F5 Stress-signaling pathways in C ENSG00000070831 ENSG00000185591 PMC5445269__F3 Genetic variation in neurodegenerative diseases and its accessibility in the model organism Caenorhabditis elegans ENSG00000118515 ENSG00000158828 PMC8001543__F4 IL-7 effect on restoring 4-1BB signal transducer in HCV-specific CD8 T cells ENSG00000105329 ENSG00000134982 ENSG00000056558 ENSG00000105656 PMC5528541__F9 A working model of Lhx2‐induced tumor progression PMC7118498__F2 TGFB 1 acts as a double-edged sword ENSG00000170365 ENSG00000105329 PMC6994220__F1 cis-carotene biosynthesis and regulation of PLB formation during skotomorphogenesis ENSG00000140543 ENSG00000117322 ENSG00000127948 PMC7289600__F3 ERK and tested pathways ENSG00000076864 ENSG00000146648 PMC7118498__F1 TGFB 1 acts as a double-edged sword ENSG00000177169 ENSG00000019991 ENSG00000170365 ENSG00000169554 ENSG00000137673 ENSG00000134982 ENSG00000138798 ENSG00000125538 ENSG00000198793 ENSG00000136997 ENSG00000145321 PMC7326812__F5 Ingenuity pathway analysis (IPA) ENSG00000157557 ENSG00000119138 ENSG00000204103 ENSG00000135100 ENSG00000167074 PMC10244118__F8 Ly6D facilitates chemoresistance in laryngeal squamous cell carcinoma through miR-509/Beta-catenin signaling pathway ENSG00000167656 ENSG00000103222 ENSG00000168036 ENSG00000168646 PMC9218441__F2 Intestinal strictures in Crohn’s disease: a 2021 update ENSG00000167207 ENSG00000145623 ENSG00000134982 ENSG00000163914 ENSG00000168036 ENSG00000067900 ENSG00000168610 PMC7575565__F6 RNF180 mediates STAT3 activity by regulating the expression of RhoC via the proteasomal pathway in gastric cancer cells ENSG00000019991 ENSG00000164197 ENSG00000168610 PMC7019846__F2 Muscle protein synthesis and degradation signaling by omega 3 fatty acids (FA) ENSG00000042832 ENSG00000169047 ENSG00000198793 PMC7146513__F1 Specialized Pro-resolving Mediator (SPM) synthesis pathway and receptors ENSG00000170775 ENSG00000171049 PMC10538533__F1 Updated roles of cGAS-STING signaling in autoimmune diseases ENSG00000164430 PMC6781272__F1 Generalized Toll-like receptor signaling mechanism, adapted from ENSG00000174123 ENSG00000174125 ENSG00000150455 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172005 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC3303816__F3 Identification of Common Biological Pathways and Drug Targets Across Multiple Respiratory Viruses Based on Human Host Gene Expression Analysis ENSG00000147044 ENSG00000181788 ENSG00000109670 PMC6224709__F4 Central carbon metabolism pathways in daf-2 and eat-2 mutants ENSG00000100412 ENSG00000146701 PMC7393405__F1 Activation of the Main Innate Immune Receptors Involved in CVDs(A) Toll-like receptor (TLR) signaling pathway ENSG00000162711 ENSG00000167207 ENSG00000172936 ENSG00000106100 PMC2799800__F1 Scheme of the model for the mammalian cell cycle ENSG00000145604 ENSG00000117399 PMC6178170__F10 Scheme showing a possible mechanism of the alleviated TLR-mediated inflammatory responses of macrophage U937 cells to the mycobacterial infection by coinfected A549 epithelial cells ENSG00000198793 ENSG00000172936 ENSG00000175104 PMC4392729__F4 Th17 counteracts the effect of IL6 ENSG00000112715 ENSG00000113525 PMC2948187__F1 Altered cellular pathways and processes in tumours ENSG00000110395 ENSG00000198793 ENSG00000163914 ENSG00000146648 ENSG00000140464 ENSG00000132341 PMC8990939__F6 Prolonged exposure to simulated microgravity promotes stemness impairing morphological, metabolic and migratory profile of pancreatic cancer cells: a comprehensive proteomic, lipidomic and transcriptomic analysis ENSG00000070831 ENSG00000169710 ENSG00000115419 PMC5779878__F6 The potential signaling pathways used by bufalin to induce apoptosis in SCC-4 human tongue cancer cells PMC6590709__F5 Glycosylation in health and disease ENSG00000146648 ENSG00000026103 PMC8892604__F3 Deep Insight Into Regulatory T Cell Metabolism in Renal Disease: Facts and Perspectives ENSG00000135218 ENSG00000115419 PMC5765504__F5 PPARG signaling ENSG00000113889 ENSG00000138029 ENSG00000143839 ENSG00000151365 ENSG00000173702 ENSG00000125084 ENSG00000062282 ENSG00000157184 ENSG00000164879 ENSG00000117054 ENSG00000167772 ENSG00000009950 ENSG00000178537 ENSG00000170522 ENSG00000140876 ENSG00000182035 ENSG00000115461 ENSG00000143632 ENSG00000164342 PMC11790812__F3 Apoptosis of tumor cell induced by Dioscin ENSG00000149311 ENSG00000002330 PMC11356641__F4 Signaling pathway involved in probiotics recognition ENSG00000174125 ENSG00000134070 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC11790812__F4 Dioscin regulating autophagy in tumor cells ENSG00000198793 PMC5409000__F6 Epidermal growth factor receptor (EGFR), signal transducer and activator of transcription 3 (STAT3), and Src-YES-associated protein 1 (YAP1) crosstalk ENSG00000291971 ENSG00000173039 ENSG00000127191 ENSG00000168610 ENSG00000146648 ENSG00000089159 PMC7822898__F6 Construction of lncRNA-related PPI networks linked to drug responsiveness in DLBCL ENSG00000100906 ENSG00000143379 ENSG00000198793 ENSG00000099385 ENSG00000171791 ENSG00000168610 PMC6888083__F6 Mutual regulatory mechanisms among lncRNAs and miRNAs ENSG00000063978 ENSG00000115266 ENSG00000183579 ENSG00000133740 PMC7372134__F3 HO-1 dysregulation in cystic fibrosis (CF) ENSG00000178573 PMC7372134__F2 Hmox1 transcriptional regulation ENSG00000178573 ENSG00000156273 ENSG00000079999 PMC5081262__F2 Major metabolic pathways in fatty acid metabolism: A) de novo lipogenesis and B) Polyunsaturated fatty acid metabolism ENSG00000169710 ENSG00000099194 PMC3514907__F3 GeneGo “Cell Adhesion_ECM remodeling” pathway map ENSG00000100234 ENSG00000137673 ENSG00000011422 ENSG00000156103 ENSG00000138798 ENSG00000026508 ENSG00000102996 ENSG00000146648 ENSG00000122194 ENSG00000104368 ENSG00000135919 PMC4639852__F9 Human mesenchymal stem cell-engineered hepatic cell sheets accelerate liver regeneration in mice ENSG00000168610 ENSG00000146648 PMC11125634__F3 Schematic representation for DOCK11 and its partner AGAP2 regulating ARF1 activity to facilitate HBV retrograde trafficking ENSG00000135439 ENSG00000143761 ENSG00000147251 ENSG00000146648 PMC11125634__F4 Proposed hypothesis explains the mechanism for the role of DOCK11 in HBV cccDNA formation and its modulation of histone modifications and RNA Pol II on HBV cccDNA ENSG00000175054 ENSG00000070831 ENSG00000132646 ENSG00000147251 PMC8204904__F5 Proposed signaling pathway that involves slit2/Robo2 and Nox2 activation during retinotectal pathfinding ENSG00000145147 ENSG00000185008 PMC2854285__F1 mTOR and cancer: many loops in one pathway ENSG00000002330 ENSG00000155792 PMC10647618__F1 Canonical Hedgehog Signaling Pathway ENSG00000128602 PMC4199881__F1 Role of GKN1 in gastric cancer ENSG00000168036 ENSG00000169605 ENSG00000064012 ENSG00000164305 PMC6471725__F6 Cinobufagin-induced effects on hepatocellular carcinoma Huh-7 cells with mutant p53 ENSG00000165119 ENSG00000134057 ENSG00000132646 ENSG00000087586 PMC5190133__F1 Cell apoptosis, autophagy and necroptosis in osteosarcoma treatment ENSG00000150907 ENSG00000111653 ENSG00000168036 ENSG00000168040 PMC3061066__F7 Model demonstrating the possible mode of action of hSSB1 ENSG00000149311 PMC5966718__F2 Detoxification of ammonia in the urea cycle and production of ornithine ENSG00000036473 PMC9007670__F2 Pathophysiological Mechanisms Underlying Multiple Organ Dysfunction in Cytokine Release Syndrome ENSG00000278718 ENSG00000162711 ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC4287682__F1 MiR-15 family and its targets in the INSR signalling pathway ENSG00000131473 ENSG00000171105 ENSG00000002330 ENSG00000110395 ENSG00000106070 ENSG00000169047 ENSG00000141564 PMC8110006__F4 Toward Colorectal Cancer Biomarkers: The Role of Genetic Variation, Wnt Pathway, and Long Noncoding RNAs ENSG00000156076 ENSG00000106483 ENSG00000277641 PMC3227936__F1 EGFR signaling pathway ENSG00000163235 ENSG00000113070 ENSG00000138798 PMC8110006__F5 Toward Colorectal Cancer Biomarkers: The Role of Genetic Variation, Wnt Pathway, and Long Noncoding RNAs ENSG00000156076 ENSG00000106483 PMC8110006__F3 Toward Colorectal Cancer Biomarkers: The Role of Genetic Variation, Wnt Pathway, and Long Noncoding RNAs PMC8258236__F2 Possible role of arsenic and gene-arsenic interactions in susceptibility to breast cancer: a systematic review ENSG00000164362 ENSG00000185591 ENSG00000146648 ENSG00000140443 PMC6600422__F2 Leptin receptor signaling is mediated by JAK-STAT, PI3K-Akt, and SHP2-ERK pathway ENSG00000169047 ENSG00000168610 PMC4283135__F1 Canonical Notch signaling with points of intervention of current therapies ENSG00000168214 ENSG00000137845 ENSG00000182667 PMC3392028__F3 Seven important signaling networks of osteoblast differentiation ENSG00000152266 ENSG00000196411 ENSG00000128272 ENSG00000105329 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000198742 PMC3392028__F1 Transcription factors and signaling involved in the osteoblast differentiation pathway ENSG00000178860 ENSG00000253293 ENSG00000137834 ENSG00000138795 ENSG00000134982 ENSG00000120149 ENSG00000168036 ENSG00000081189 ENSG00000170365 ENSG00000128272 ENSG00000115415 ENSG00000198742 ENSG00000114315 ENSG00000163501 ENSG00000105996 PMC9462519__F6 Extracellular Vesicles: The Next Generation Theranostic Nanomedicine for Inflammatory Bowel Disease ENSG00000125538 ENSG00000136869 ENSG00000106100 PMC5364541__F8 Schisandrin A inhibits dengue viral replication via upregulating antiviral interferon responses through STAT signaling pathway ENSG00000213928 ENSG00000089127 ENSG00000115415 ENSG00000111331 PMC4283135__F2 Notch signaling modules relevant for brain tumors ENSG00000041982 ENSG00000078747 ENSG00000133961 ENSG00000146648 PMC4586474__F3 TGF-Beta-IDO-SHP axis ENSG00000104856 ENSG00000105329 ENSG00000136869 ENSG00000184216 ENSG00000106546 PMC7193415__F8 GR Ser134 phosphorylation creates a feedforward signaling loop that potentiates further activation of the p38 MAPK pathway downstream of TGFB1 in TNBC models ENSG00000128272 ENSG00000143768 ENSG00000100100 ENSG00000155090 PMC7764600__F2 Most important signaling molecules characterizing EBV + GC ENSG00000117713 ENSG00000019991 ENSG00000138798 ENSG00000198793 ENSG00000146648 ENSG00000167771 PMC4586474__F1 Pathways of tryptophan metabolism ENSG00000188676 PMC7764600__F3 Cellular degradation pathway of autophagy plays a fundamental role in immunity ENSG00000239732 ENSG00000198793 ENSG00000136869 PMC2636986__F1 Adaptor protein containing pleckstrin homology (PH) domain, phosphotyrosine-binding (PTB) domain, and leucine zipper motif (APPL1)-mediated adiponectin and insulin-signaling pathways ENSG00000157500 ENSG00000143878 ENSG00000198793 ENSG00000159346 PMC5853489__F3 DAL81 regulates expression of arginine metabolism in C. parapsilosis ENSG00000091704 ENSG00000081181 ENSG00000118520 ENSG00000158516 PMC6875424__F8 Possible mechanisms of the effects of methane against APAP-induced hepatic injury ENSG00000142192 ENSG00000181019 ENSG00000079999 PMC8245375__F5 Genetic predisposition in the 2′-5′A pathway in the development of type 1 diabetes: potential contribution to dysregulation of innate antiviral immunity ENSG00000213928 ENSG00000187608 ENSG00000115415 ENSG00000183486 ENSG00000157601 ENSG00000136869 ENSG00000135828 ENSG00000175104 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC3032315__F3 Regulation of peripheral tolerance by the intrinsic and extrinsic apoptosis pathways in T and B cells ENSG00000134982 ENSG00000186716 ENSG00000171791 ENSG00000104081 PMC3198933__F1 Toll-like receptor (TLR) signaling ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000164342 PMC6473131__F1 Possible mechanisms of cancers caused by Porphyromonas gingivalis ENSG00000262406 ENSG00000125538 ENSG00000168610 PMC8687455__F7 Analysis of Wheat Wax Regulation Mechanism by Liposome and Transcriptome ENSG00000065357 ENSG00000042832 PMC8013702__F3 MuV infection of testicular somatic cells and downstream effects ENSG00000169245 ENSG00000187608 ENSG00000157601 PMC12145571__F2 Skeletal muscle atrophy is a multifactorial process that essentially results from a disturbance in the equilibrium between protein anabolism and catabolism ENSG00000177169 ENSG00000170365 ENSG00000198793 PMC4179679__F3 Metabostemness: a metabolo-epitranscriptional switcher ENSG00000147162 ENSG00000077463 ENSG00000096717 PMC12085564__F7 Cardiomyocyte specific CD38 deletion protecting heart from acute myocardial infarction ENSG00000116688 ENSG00000171791 ENSG00000142082 ENSG00000171109 PMC6538211__F2 Illustration of the WNK-SPAK/OSR1-CCCs cascade in nervous and non-nervous system diseases ENSG00000126562 ENSG00000060237 PMC11727142__F9 Osteoblast‐Derived ECM1 Promotes Anti‐Androgen Resistance in Bone Metastatic Prostate Cancer ENSG00000074800 ENSG00000115904 PMC4216607__F1 Management of Pediatric and Adult Patients with Medulloblastoma ENSG00000134982 ENSG00000135446 ENSG00000136997 ENSG00000164690 ENSG00000128602 PMC4706649__F2 Different apoptotic pathways are modulated by PEDF ENSG00000132906 ENSG00000171791 ENSG00000168040 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC5906968__F1 Schematic representation of the regulatory pathways affecting gene expression during mouse spermatogenesis PMC5279772__F6 Inhibition of NFKB Pathway and Modulation of MAPK Signaling Pathways in Glioblastoma and Implications for Lovastatin and Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL) Combination Therapy ENSG00000173039 ENSG00000168040 PMC4681408__F6 Patient-specific Immune States before Surgery are Strong Correlates of Surgical Recovery ENSG00000162889 ENSG00000170458 ENSG00000173039 ENSG00000189403 ENSG00000136869 PMC10605590__F7 The potential non-genomic P4 action in colorectal cancer ENSG00000163464 ENSG00000164040 ENSG00000117691 ENSG00000082175 PMC4693471__F2 Gene‐by‐age interaction miRNA–mRNA network analysis ENSG00000184347 ENSG00000135439 ENSG00000138083 ENSG00000136854 ENSG00000163132 ENSG00000171791 ENSG00000168267 ENSG00000121966 ENSG00000005810 ENSG00000144802 ENSG00000084676 ENSG00000178573 ENSG00000184384 ENSG00000150907 ENSG00000184634 ENSG00000170921 ENSG00000220205 ENSG00000008300 ENSG00000189403 ENSG00000176165 ENSG00000065802 ENSG00000172238 ENSG00000138795 ENSG00000039560 ENSG00000015153 ENSG00000148400 ENSG00000179242 ENSG00000135622 ENSG00000077279 ENSG00000149091 ENSG00000143458 ENSG00000065320 ENSG00000007866 ENSG00000115310 ENSG00000168016 ENSG00000164532 ENSG00000102003 ENSG00000173210 ENSG00000132639 ENSG00000145920 ENSG00000101745 ENSG00000124785 ENSG00000185652 ENSG00000180447 ENSG00000102034 ENSG00000144857 ENSG00000292254 ENSG00000149480 PMC2576563__F7 Tight regulation of MUC5AC mucin induction by pneumolysin via PAK4-JNK and MKP1 signaling pathways ENSG00000291363 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000130669 PMC8510947__F2 STAT3 and its role in cardioprotection by conditioning: focus on non-genomic roles targeting mitochondrial function ENSG00000156026 ENSG00000168610 PMC10960729__F4 Activation and inhibition of the cGAS–STING signaling pathway in viral infection ENSG00000183735 ENSG00000164430 ENSG00000125538 ENSG00000197594 PMC10960729__F5 Tumor suppression and promotion of the cGAS–STING signaling pathway ENSG00000164430 ENSG00000139618 PMC10960729__F2 Triggers of cGAS–STING signaling pathway ENSG00000164430 PMC10960729__F3 Signal transduction mechanism of cGAS–STING ENSG00000183735 ENSG00000164430 PMC5874524__F8 LGM2605 inhibition of asbestos-induced NLRP3 inflammasome activation by blocking asbestos-induced reactive oxygen species (ROS) generation and activating the Nrf2-ARE pathway ENSG00000162711 ENSG00000181019 ENSG00000125538 ENSG00000079999 PMC8649885__F1 Schematic showing the reported genetic determinants of human EEA and EEAF ENSG00000273992 ENSG00000261456 ENSG00000280949 ENSG00000172680 ENSG00000203908 PMC5447385__F7 HMGB1-RAGE pathway drives peroxynitrite signaling-induced IBD-like inflammation in murine nonalcoholic fatty liver disease ENSG00000164902 ENSG00000189403 ENSG00000136869 PMC3521387__F9 ILOCi detected genes from T1D and their maps in 'type I diabetes mellitus' pathway ENSG00000111537 ENSG00000179344 ENSG00000277263 ENSG00000180644 PMC3521387__F7 ILOCi detected genes from BD and their maps in 'neuroactive ligand-receptor interaction' pathway ENSG00000004948 ENSG00000198670 ENSG00000102468 ENSG00000104368 PMC3521387__F8 ILOCi detected genes from CAD and their maps in 'cytokine-cytokine receptor interaction' pathway ENSG00000226275 ENSG00000099985 ENSG00000281857 ENSG00000127948 ENSG00000026103 PMC11964952__F2 Proposed chart of T1D dual vulnerability initiated by Beta-cell metabolic dysfunction and CD4+ T-cell activation ENSG00000103811 ENSG00000278718 ENSG00000159224 ENSG00000105397 ENSG00000144895 ENSG00000134982 ENSG00000107249 ENSG00000265972 ENSG00000100219 ENSG00000162772 PMC11964952__F3 T1D targets for therapeutic interventions in endocrine cells ENSG00000162711 ENSG00000002330 ENSG00000288269 ENSG00000113070 ENSG00000265972 ENSG00000157005 ENSG00000118971 ENSG00000010310 ENSG00000004848 ENSG00000135446 ENSG00000139515 ENSG00000115263 ENSG00000163623 ENSG00000146648 PMC11964952__F4 T1D targets for therapeutic interventions in immune cells ENSG00000177455 ENSG00000138378 ENSG00000111537 ENSG00000197635 ENSG00000134982 ENSG00000137265 ENSG00000103522 ENSG00000265972 ENSG00000182759 ENSG00000095794 PMC10378789__F2 Revisiting the Role of Autophagy in Cardiac Differentiation: A Comprehensive Review of Interplay with Other Signaling Pathways ENSG00000177169 ENSG00000152348 ENSG00000039537 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000171791 ENSG00000145782 ENSG00000057663 PMC8773620__F1 Molecular Targeted Therapies: Time for a Paradigm Shift in Medulloblastoma Treatment? ENSG00000164690 ENSG00000128602 PMC4051158__F1 Role of the CD40–CD40L pathway during the CD8 primary response ENSG00000134982 PMC8840228__F2 Muscle stem cell adaptations to cellular and environmental stress ENSG00000180210 ENSG00000128272 PMC8840228__F3 Muscle stem cell adaptations to cellular and environmental stress PMC9102653__F2 Subversion of the immune response of human pathogenic spirochetes ENSG00000009724 ENSG00000288512 ENSG00000244731 ENSG00000182326 ENSG00000236625 PMC9330218__F3 Targeting SREBP-1-Mediated Lipogenesis as Potential Strategies for Cancer ENSG00000131473 ENSG00000130164 ENSG00000138798 ENSG00000198793 ENSG00000113161 ENSG00000169710 ENSG00000173976 ENSG00000099194 ENSG00000096717 PMC4051158__F5 The CD40-CD40L pathway plays a critical role in CD4 T-cell–mediated IL-21 production during the rescue of exhausted T-cell response ENSG00000103522 PMC7754534__F6 Proposed model of adenine-activated-hepcidin axis Adenine induces activation of cAMP/PKA signaling pathway, which in trun stimulates the activation of both SMAD1/5/8 pathways resulting in transcritional activation of hepcidin gene expression ENSG00000170365 ENSG00000105697 PMC3706439__F2 Fermentation of Xylose Causes Inefficient Metabolic State Due to Carbon/Energy Starvation and Reduced Glycolytic Flux in Recombinant Industrial Saccharomyces cerevisiae ENSG00000122966 ENSG00000172005 ENSG00000102977 PMC9382032__F7 Genetic and transcriptome analyses reveal the candidate genes and pathways involved in the inactive shade-avoidance response enabling high-density planting of soybean ENSG00000169291 ENSG00000172005 PMC4983807__F4 Members of receptor tyrosine signaling pathways that are predicted as indispensable nodes and targeted by cancer mutations, OMIM disease, viruses, or FDA-approved drugs ENSG00000140992 ENSG00000070831 ENSG00000050748 ENSG00000169047 ENSG00000115904 ENSG00000171791 ENSG00000169032 ENSG00000166484 ENSG00000141968 ENSG00000077150 ENSG00000149269 ENSG00000136997 ENSG00000105810 ENSG00000077782 ENSG00000139687 ENSG00000140443 ENSG00000171105 ENSG00000005339 ENSG00000065361 ENSG00000065559 ENSG00000160691 ENSG00000133216 ENSG00000177606 ENSG00000161202 ENSG00000146648 PMC5495464__F3 Interactions of IGF and ERB signaling pathways in malignancy ENSG00000197081 ENSG00000138798 ENSG00000169047 ENSG00000198793 ENSG00000168610 ENSG00000146648 ENSG00000140443 PMC4458429__F2 Preclinical and clinical studies of the NEDD9 scaffold protein in cancer and other diseases ENSG00000111859 ENSG00000291971 ENSG00000198793 ENSG00000099942 ENSG00000089159 PMC9302318__F6 Network pharmacology analysis of molecular targets and related mechanisms of Guizhi decoction in treating of menopausal syndrome ENSG00000087095 ENSG00000170458 ENSG00000102871 ENSG00000130522 ENSG00000138798 ENSG00000130159 ENSG00000127191 ENSG00000132341 ENSG00000026103 PMC9302318__F7 Network pharmacology analysis of molecular targets and related mechanisms of Guizhi decoction in treating of menopausal syndrome ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000002330 ENSG00000069482 ENSG00000179091 ENSG00000186716 ENSG00000198793 ENSG00000136997 ENSG00000104894 PMC8709142__F1 Beneficial Properties of Bromelain ENSG00000002330 PMC6236434__F4 Mechanisms mostly deemed to contribute to the development of APAs ENSG00000138795 ENSG00000281324 ENSG00000253506 ENSG00000162337 ENSG00000134982 ENSG00000179142 ENSG00000168036 PMC6535783__F1 RNF8 involves in DSB signaling pathway ENSG00000188486 ENSG00000149311 ENSG00000083093 ENSG00000163961 ENSG00000051180 ENSG00000127334 ENSG00000112130 ENSG00000111642 PMC11499591__F3 ApoM/S1P, Wnt/beta-catenin, and PI3K/AKT/mTOR signaling pathways involved in intestinal barrier damage ENSG00000198793 ENSG00000168036 ENSG00000142082 PMC4398256__F1 MTOR signaling and metabolic regulation ENSG00000291603 ENSG00000010810 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC8466097__F2 Plant-Based Antioxidant Extracts and Compounds in the Management of Oral Cancer ENSG00000002330 ENSG00000132646 ENSG00000198793 ENSG00000120868 PMC8771504__F6 Chronic stress model simulated by salbutamol promotes tumorigenesis of gastric cancer cells through B2-AR/ERK/EMT pathway ENSG00000170558 PMC5308218__F4 Proximal Signaling Network of the BCR-ABL1 Oncogene Shows a Modular Organization ENSG00000123338 ENSG00000033327 ENSG00000111859 ENSG00000158195 ENSG00000105647 ENSG00000099942 ENSG00000179295 ENSG00000107263 ENSG00000092621 ENSG00000198087 ENSG00000071051 ENSG00000172380 ENSG00000186298 ENSG00000160691 ENSG00000065978 ENSG00000110395 ENSG00000055163 ENSG00000186716 ENSG00000116489 ENSG00000072110 ENSG00000135407 ENSG00000127824 ENSG00000127527 ENSG00000213672 ENSG00000140848 ENSG00000135605 ENSG00000115145 ENSG00000154237 PMC3257580__F1 Kruppel-like factors in lymphocyte biology ENSG00000127528 ENSG00000109787 ENSG00000136826 ENSG00000155090 PMC12081410__F11 Bioactive compound combinations from Rhodiola tangutica alleviate pulmonary vascular remodeling in high-altitude pulmonary hypertension rats through the PI3K–AKT pathway ENSG00000140992 ENSG00000135446 ENSG00000132646 ENSG00000123374 PMC6527596__F1 The regulatory mechanism of miRNAs in TLR signaling ENSG00000174123 ENSG00000174125 ENSG00000109320 ENSG00000170677 ENSG00000239732 ENSG00000125538 ENSG00000134070 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000090376 ENSG00000184216 ENSG00000164342 PMC11653707__F1 MTOR signaling in activating TME cells ENSG00000198793 ENSG00000146648 PMC3518582__F3 Wnt7a signals bidirectionally through divergent pathways to influence both presynaptic and postsynaptic assembly and to promote excitatory synapse formation and function ENSG00000154764 PMC6363035__F3 Schematic Representation of DDR1-collagen signaling pathway in cancer ENSG00000169908 ENSG00000291971 ENSG00000170558 ENSG00000114315 ENSG00000168610 PMC3518582__F1 Wnt Signal Transduction Pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC5357236__F1 microRNAs in lipoprotein metabolism and cardiometabolic disorders ENSG00000167910 ENSG00000073734 ENSG00000160179 PMC3710321__F1 Regulation of STATs by polycystin-1 and their role in polycystic kidney disease ENSG00000019991 ENSG00000115415 ENSG00000291971 ENSG00000138798 ENSG00000113520 ENSG00000168610 PMC3124048__F1 Parallels in haematopoiesis between the Drosophila LG and mammalian bone marrow ENSG00000170558 PMC9366230__F8 Cell membrane coated-nanoparticles for cancer immunotherapy ENSG00000087842 PMC5392015__F4 GHRP mechanism of action ENSG00000135218 ENSG00000105329 ENSG00000130234 ENSG00000198793 PMC10671516__F3 Granulosa cell glucose and lipid metabolism on oocytes ENSG00000173992 PMC11988865__F6 Regulatory mechanisms of Brandt’s vole brain tissue in response to hypoxia ENSG00000002330 ENSG00000136826 PMC7723926__F1 Schematic depiction of unfolded protein response (UPR) signaling cascade, and the interplay between endoplasmic reticulum (ER) stress response and inflammation ENSG00000162711 ENSG00000100220 ENSG00000128272 ENSG00000144895 ENSG00000265972 ENSG00000100219 PMC3759367__F11 Signaling pathway and proposed sites of arsenite perturbation ENSG00000170365 ENSG00000186395 ENSG00000109101 ENSG00000148400 ENSG00000167768 ENSG00000138798 ENSG00000158050 PMC3158097__F1 Association Analysis of Canonical Wnt Signalling Genes in Diabetic Nephropathy ENSG00000134982 ENSG00000168036 PMC10671516__F1 Paracrine-mediated signaling between granulosa cells and oocytes ENSG00000132906 ENSG00000170365 ENSG00000170961 ENSG00000164404 ENSG00000130385 ENSG00000163661 PMC3638465__F1 Metabolic map showing selected pathways of D ENSG00000182511 ENSG00000110395 ENSG00000155926 PMC5983649__F1 Schematic overview of Annexins at the crossroad of late endocytic pathways ENSG00000131748 ENSG00000177058 ENSG00000135823 ENSG00000141458 PMC3737723__F8 Model of the Prdm1a gene regulatory network for NCC specification ENSG00000030582 ENSG00000183979 ENSG00000137203 ENSG00000187140 ENSG00000100146 PMC8508234__F9 Therapeutic and Prognostic Values of LSM Family Genes in Breast Cancer ENSG00000149311 ENSG00000179091 ENSG00000134982 ENSG00000132341 PMC6895975__F2 Extracellular regulation of mesendodermal gene expression ENSG00000124479 ENSG00000156574 ENSG00000179284 PMC3070849__F1 Emergence of the PI3-kinase pathway as a central modulator of normal and aberrant B cell differentiation ENSG00000177455 ENSG00000095585 ENSG00000124102 ENSG00000140968 ENSG00000150907 ENSG00000137265 ENSG00000010671 PMC4020801__F3 Proteomics of Vitreous Humor of Patients with Exudative Age-Related Macular Degeneration ENSG00000211445 ENSG00000113905 ENSG00000117601 ENSG00000181418 ENSG00000171560 ENSG00000163631 PMC4441360__F6 EGFR/ErbB3 Pathway Acts as a Compensatory Survival Mechanism upon c-Met Inhibition in Human c-Met+ Hepatocellular Carcinoma ENSG00000065361 ENSG00000163235 ENSG00000146648 PMC7746484__F1 Toll-like receptor (TLR) signaling pathways ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC9516464__F2 Strategies to improve the effect of mesenchymal stem cell therapy on inflammatory bowel disease ENSG00000178860 ENSG00000138755 ENSG00000118520 ENSG00000166090 ENSG00000164342 PMC4250281__F1 Cellular signaling through pre-organized and inter-connected nanocluster assemblies with gel-like properties ENSG00000070831 ENSG00000134982 ENSG00000140575 ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC9304635__F2 Diosgenin and Its Analogs: Potential Protective Agents Against Atherosclerosis ENSG00000138075 ENSG00000135218 ENSG00000130164 ENSG00000042832 ENSG00000167910 ENSG00000015520 ENSG00000096717 ENSG00000169174 ENSG00000143921 ENSG00000262243 PMC8797823__F5 Frizzled receptor expression on patients’ survival with gastrointestinal cancers: A systematic review with meta-analysis ENSG00000134982 ENSG00000163914 PMC5983650__F9 Bornyl cis-4-hydroxycinnamate-induced apoptotic pathway ENSG00000128272 ENSG00000002330 ENSG00000144895 PMC8799916__F2 Skin cancer biology and barriers to treatment: Recent applications of polymeric micro/nanostructures ENSG00000106571 ENSG00000002330 ENSG00000291971 ENSG00000010810 ENSG00000128602 ENSG00000146648 PMC11568601__F9 Tongguanteng injection exerts anti-osteosarcoma effects through the ER stress-associated IRE1/CHOP pathway ENSG00000143799 ENSG00000100219 PMC4673555__F4 Proposed GC-C signaling in colitis ENSG00000165556 ENSG00000135100 ENSG00000172572 ENSG00000066230 ENSG00000001626 ENSG00000044012 ENSG00000070019 PMC7684869__F2 Schematic figure of NPY and leptin in local homeostasis of bone remodeling PMC5454045__F2 FGF signaling pathway ENSG00000244405 ENSG00000175832 ENSG00000177606 PMC6523677__F2 MicroRNA-mRNA network constructed using CyTargetLinker ENSG00000167325 ENSG00000171848 ENSG00000158825 ENSG00000129187 PMC3342058__F2 Major therapeutic targets for inhibition of donor-reactive memory T cell responses ENSG00000139193 ENSG00000198793 PMC6775293__F8 Pathway of Alzheimer's disease ENSG00000132906 ENSG00000291983 ENSG00000142192 ENSG00000002330 ENSG00000120868 ENSG00000168040 ENSG00000119912 ENSG00000125347 ENSG00000164305 PMC4178318__F10 Schematic of Rab23 functions in chondrogenic cells ENSG00000125398 ENSG00000112210 PMC4837341__F4 Drug target identification using network analysis in Sini decoction ENSG00000100253 ENSG00000134824 ENSG00000276870 ENSG00000100078 ENSG00000291994 ENSG00000172482 ENSG00000070669 ENSG00000178445 ENSG00000241878 ENSG00000084774 ENSG00000133027 PMC9271168__F2 C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways ENSG00000152348 ENSG00000284774 ENSG00000123395 ENSG00000160551 ENSG00000067369 ENSG00000114019 ENSG00000070669 ENSG00000124762 ENSG00000057663 ENSG00000162298 ENSG00000183765 ENSG00000128165 ENSG00000178607 ENSG00000134086 ENSG00000089154 ENSG00000153879 ENSG00000144848 ENSG00000100219 ENSG00000145782 ENSG00000168209 ENSG00000116044 ENSG00000086232 ENSG00000079999 ENSG00000149311 ENSG00000128272 ENSG00000158615 ENSG00000144895 ENSG00000177606 ENSG00000198517 ENSG00000128829 ENSG00000196365 ENSG00000198625 PMC7330693__F8 GINS2 interference induces apoptosis and cell cycle arrest ENSG00000135446 ENSG00000131153 PMC7382369__F4 Ex vivo and in vivo stable isotope labelling of central carbon metabolism and related pathways with analysis by LC–MS/MS ENSG00000102967 ENSG00000084774 PMC3168773__F2 Functional relationship linking Crb proteins to the SWH pathway ENSG00000130545 PMC9655342__F3 Targeted Therapies in Advanced and Metastatic Urothelial Carcinoma ENSG00000066468 ENSG00000065361 ENSG00000160867 ENSG00000149269 ENSG00000077782 ENSG00000178568 PMC8971665__F4 Retinoblastoma Protein Paralogs and Tumor Suppression ENSG00000112576 ENSG00000103479 ENSG00000135446 ENSG00000123374 ENSG00000100526 ENSG00000105810 ENSG00000118971 ENSG00000139687 ENSG00000080839 ENSG00000175305 PMC6232344__F3 Compounds and hitting targets on ICH ENSG00000132906 ENSG00000162711 ENSG00000136869 PMC6039985__F3 In PDA cells, E47 directed an integrated program of gene expression that controlled cell-cycle progression ENSG00000261857 PMC2939298__F1 Schematic diagram of androgen biosynthesis ENSG00000135437 ENSG00000151632 ENSG00000203859 PMC7956267__F2 Transcriptional regulation involved in activating salt stress-responsive genes in rice ENSG00000105722 ENSG00000102974 PMC6557283__F2 YAP/TAZ signaling and resistance to chemotherapy ENSG00000108342 ENSG00000184371 ENSG00000164400 PMC6557283__F1 YAP/TAZ signaling and resistance to targeted therapy ENSG00000167601 ENSG00000141867 ENSG00000183735 ENSG00000186575 ENSG00000065361 ENSG00000197905 ENSG00000007866 ENSG00000150457 ENSG00000120162 ENSG00000146648 ENSG00000131023 ENSG00000074219 PMC7291251__F1 Upstream and downstream mTORC1 signaling ENSG00000177169 ENSG00000198793 ENSG00000145979 ENSG00000155792 ENSG00000167965 PMC5642500__F7 HCaRG/COMMD5 inhibits ErbB receptor-driven renal cell carcinoma ENSG00000134086 ENSG00000065361 ENSG00000198793 ENSG00000146648 PMC5051268__F2 Multiple Faces of FGF-23 ENSG00000111012 ENSG00000118972 ENSG00000152266 ENSG00000288499 ENSG00000130234 ENSG00000197594 ENSG00000152592 ENSG00000077782 PMC4312599__F5 Coordinately up-regulated genes of WNT signaling pathway in HCV versus HIV ENSG00000087095 ENSG00000095739 ENSG00000100387 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000168036 ENSG00000196470 PMC9366716__F2 Cell wall and the response and tolerance to stresses of biotechnological relevance in yeasts ENSG00000101871 ENSG00000149418 PMC7344072__F2 Mechanism by which proinflammatory cytokines in the OA knee joint stimulates MSCs to produce IDO1 ENSG00000115415 PMC2603552__F10 Role of oxysterol sulfation in lipid metabolism ENSG00000088002 ENSG00000026103 PMC4346193__F5 Schematic model illustrating how IGFBP-3 proteins regulate the TNFA and apoptosis pathway in REC: Right ENSG00000100234 PMC11979195__F2 Modulating oxidative stress: a reliable strategy for coping with community-acquired pneumonia in older adults ENSG00000178573 ENSG00000079999 PMC3103151__F1 Intracellular pathway of folate metabolism with highlighted critical pathways of methotrexate (MTX) entry, effect and efflux ENSG00000136877 ENSG00000196839 ENSG00000035928 ENSG00000137563 ENSG00000023839 PMC5992473__F9 Schematic Illustrates a Model of miR372 Promotes Liver Cancer Cell Growth by Upregulating erbB-2 through Enhancing YB-1 via Targeting for PTENmiR372 accelerates malignant progression of liver cancer cells in vitro and in vivo ENSG00000168036 ENSG00000123374 ENSG00000196628 ENSG00000102974 PMC8616315__F2 Multiple Interactions of RUNX with the Hippo–YAP Pathway ENSG00000020633 ENSG00000150457 ENSG00000131023 PMC6528874__F1 Anti‐tumour effect of TNFA and IFNG alone and in combination ENSG00000111537 ENSG00000120438 ENSG00000026103 PMC3382253__F4 Mitochondria biogenesis allows tissue adaption under stress PMC10750205__F2 Endosialin in Cancer: Expression Patterns, Mechanistic Insights, and Therapeutic Approaches ENSG00000173269 ENSG00000176435 PMC3382253__F3 Mitochondria are central organelles in determining cell fate in liver diseases ENSG00000120868 ENSG00000168040 PMC8899336__F1 Wnt signaling in biliary development, proliferation, and fibrosis ENSG00000138795 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC7785817__F2 Structures of Slit/Robo, and the Slit-Robo signaling pathway ENSG00000070831 ENSG00000170558 ENSG00000196935 ENSG00000168036 PMC8899336__F2 Wnt signaling in biliary development, proliferation, and fibrosis ENSG00000019991 PMC2548289__F1 Hereditary Hemochromatosis in the Post HFE Era ENSG00000010704 ENSG00000106327 PMC9562887__F2 “Sweet Spot” of Targeting Tumor Metabolism in Ovarian Cancers ENSG00000198793 ENSG00000168610 PMC5548184__F4 Heterogeneous ribosomes preferentially translate distinct subpools of mRNAs genome-wide ENSG00000280831 ENSG00000152348 ENSG00000081181 ENSG00000002330 ENSG00000134533 ENSG00000171723 ENSG00000278488 ENSG00000166484 ENSG00000182541 ENSG00000105894 ENSG00000103811 ENSG00000189171 ENSG00000266028 ENSG00000139970 ENSG00000160447 ENSG00000122862 ENSG00000140464 ENSG00000026103 ENSG00000135919 ENSG00000142192 ENSG00000285109 ENSG00000122966 ENSG00000198931 ENSG00000127837 ENSG00000160224 ENSG00000138823 ENSG00000134853 ENSG00000107611 ENSG00000185339 PMC3437636__F2 Formation of the NFKB-stimulating TNFR1 signaling complex ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC8516864__F4 Tryptophan/kynurenine pathway PMC8516864__F2 Polyamine pathway and Cadaverine pathway ENSG00000116649 ENSG00000070669 ENSG00000102172 PMC4353374__F2 SIRT1 in synaptic plasticity ENSG00000100811 ENSG00000106683 ENSG00000198793 ENSG00000096717 PMC7484393__F3 Correction: Unpuzzling COVID-19: tissue-related signaling pathways associated with SARS-CoV-2 infection and transmission ENSG00000162711 ENSG00000125538 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC11126064__F8 Hepatoprotective Effects of Allicin on Carbon Tetrachloride-Induced Acute Liver Injury in Mice by Inhibiting Oxidative Stress, Inflammation, and Apoptosis ENSG00000181019 PMC8063048__F1 Roles that dopamine receptors play in regulating inflammasome formation as well as NFKB pathway ENSG00000162711 PMC8063048__F2 Roles that dopamine receptors play in macrophages ENSG00000113520 ENSG00000168610 PMC6666404__F4 Longitudinal multi-omics of host–microbe dynamics in prediabetes ENSG00000142192 ENSG00000042832 ENSG00000015285 ENSG00000115419 PMC5418445__F1 Tumour angiogenesis: molecular pathways and potential interventional strategies ENSG00000019991 ENSG00000163914 PMC10940030__F4 Phospholipase D, a Novel Therapeutic Target Contributes to the Pathogenesis of Neurodegenerative and Neuroimmune Diseases ENSG00000033327 ENSG00000157933 ENSG00000143761 ENSG00000010810 ENSG00000198793 ENSG00000163914 PMC4538325__F3 Signaling pathways modulated by electrophilic lipids ENSG00000284774 ENSG00000178573 ENSG00000079999 PMC6321423__F3 Schematic depiction of the TGFB signaling pathway ENSG00000168610 PMC8618532__F2 Sirtuins as Metabolic Regulators of Immune Cells Phenotype and Function ENSG00000156127 ENSG00000198793 ENSG00000113520 ENSG00000096717 ENSG00000142082 PMC7718329__F7 TET1 and 5hmC in an obesity-linked pathway driving cancer stem cells in triple-negative breast cancer ENSG00000138336 PMC8740020__F3 Unfolded Protein Response in Coronavirus Infection and Its Implications for Drug Design ENSG00000144895 PMC3686733__F2 Proteomic View of Interactions of Shiga Toxin-Producing Escherichia coli with the Intestinal Environment in Gnotobiotic Piglets ENSG00000197487 PMC2575825__F9 Redox-sensitive steps in hypothetical redox signaling pathways ENSG00000163235 ENSG00000291971 ENSG00000136869 ENSG00000146648 PMC7041777__F3 Interactions between AB, WNT pathway and energy metabolism in AD ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000110435 PMC8740020__F2 Unfolded Protein Response in Coronavirus Infection and Its Implications for Drug Design ENSG00000128272 ENSG00000100219 ENSG00000162772 PMC2575825__F4 Glutathionine (GSH) redox network ENSG00000001626 ENSG00000148344 ENSG00000103253 ENSG00000146648 ENSG00000023572 ENSG00000114115 PMC3739939__F4 Pathway analysis showing integration between signaling pathways, transcription factors, and adhesion genes ENSG00000169554 ENSG00000124216 ENSG00000122691 ENSG00000019549 ENSG00000288335 ENSG00000100146 PMC6933333__F7 LncRNA TNRC6C‐AS1 silencing inhibits proliferation and promotes apoptosis and autophagy of TC cells ENSG00000101109 ENSG00000150457 ENSG00000131023 PMC5516868__F1 Snf1 pathway and its components ENSG00000196511 ENSG00000284774 ENSG00000069482 ENSG00000158458 ENSG00000166278 ENSG00000177045 PMC9042615__F7 Maresin 1 Alleviates Diabetic Kidney Disease via LGR6-Mediated cAMP-SOD2-ROS Pathway ENSG00000133067 PMC4564008__F1 Regulation of Hedgehog signaling by ubiquitination PMC8076792__F1 Disrupted Lipid Metabolism in Multiple Sclerosis: A Role for Liver X Receptors? ENSG00000275385 ENSG00000116133 ENSG00000119655 ENSG00000036530 ENSG00000125538 ENSG00000113161 ENSG00000141458 ENSG00000169710 ENSG00000160179 ENSG00000099194 ENSG00000049768 ENSG00000026103 PMC8514848__F1 RASopathies: From germline mutations to somatic and multigenic diseases ENSG00000122882 ENSG00000157764 ENSG00000110395 ENSG00000198793 ENSG00000120868 ENSG00000171791 ENSG00000166068 ENSG00000196712 ENSG00000062485 PMC3798821__F6 The ILK signaling and its putative regulation by the micro-RNA-1 (miR-1) ENSG00000136997 ENSG00000019549 ENSG00000197702 PMC8787047__F3 Accentuating CircRNA-miRNA-Transcription Factors Axis: A Conundrum in Cancer Research ENSG00000100811 ENSG00000135446 ENSG00000170558 ENSG00000198793 ENSG00000105810 PMC3798821__F4 The valine degradation pathway from the differentially regulated genes in response to 3–7 days of mechanical overload ENSG00000138029 ENSG00000137992 ENSG00000113790 ENSG00000105552 ENSG00000091140 ENSG00000163884 PMC6889001__F2 Atherothrombosis and the NLRP3 Inflammasome – Endogenous Mechanisms of Inhibition ENSG00000162711 ENSG00000150782 ENSG00000136869 ENSG00000142082 ENSG00000159335 PMC3872295__F1 Mechanistic model to show how mechanical forces promote differentiation of fetal type II epithelial cells via release of soluble growth factors HB-EGF and TGFA with subsequent binding and activation of the EGFR and ERK signaling pathway ENSG00000163235 ENSG00000113070 ENSG00000146648 PMC9298356__F1 CAM photosynthesis: the acid test ENSG00000062485 PMC6595533__F2 The proposed mechanisms by which norepinephrine (NE) and corticosterone/cortisol (CORT) regulate sterile inflammation ENSG00000162711 ENSG00000168329 ENSG00000115590 ENSG00000203710 ENSG00000189403 ENSG00000173578 ENSG00000115594 PMC8471002__F4 Fibroblast Activation and Myocardial Fibrosis: Lessons Learned from FB-Specific Conditional Mouse Models ENSG00000150457 ENSG00000131023 PMC3334885__F1 T Regulatory Cells Control Susceptibility to Invasive Pneumococcal Pneumonia in Mice ENSG00000137804 ENSG00000115163 ENSG00000105329 ENSG00000143815 ENSG00000105699 ENSG00000112742 ENSG00000184205 PMC5334311__F1 The compensatory B‐cell proliferative signaling network mediated by insulin resistance ENSG00000118971 PMC8471002__F2 Fibroblast Activation and Myocardial Fibrosis: Lessons Learned from FB-Specific Conditional Mouse Models ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC8471002__F1 Fibroblast Activation and Myocardial Fibrosis: Lessons Learned from FB-Specific Conditional Mouse Models ENSG00000137834 ENSG00000134982 ENSG00000168036 PMC8204080__F1 O-GlcNAcylation in Hyperglycemic Pregnancies: Impact on Placental Function ENSG00000147162 ENSG00000198408 ENSG00000169047 PMC10999050__F3 Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analysis ENSG00000132906 ENSG00000150907 ENSG00000125538 ENSG00000136997 ENSG00000173039 ENSG00000143933 ENSG00000073756 ENSG00000168610 ENSG00000064012 ENSG00000164305 ENSG00000124762 PMC7699474__F3 Protein interaction networks (PPIs) for ploidy associated c-MYC -interacting bivalent genes ENSG00000095585 ENSG00000136997 PMC8961648__F4 Multi-Omics Analysis of Multiple Glucose-Sensing Receptor Systems in Yeast ENSG00000118520 ENSG00000124253 PMC8177011__F7 Expression of Nutrient Transporters on NK Cells During Murine Cytomegalovirus Infection Is MyD88-Dependent ENSG00000137033 ENSG00000172936 PMC5955790__F1 Tumor necrosis factor A (TNF) regulation in health and disease and its sleep-linked effectors and actions ENSG00000125571 ENSG00000291972 ENSG00000113520 PMC6610925__F1 Hexosamine biosynthetic pathway ENSG00000147162 ENSG00000198408 ENSG00000013375 PMC4615139__F6 Proposed mechanism of cordycepin-induced apoptosis and cell cycle arrest in NB-4 and U937 cells ENSG00000123374 ENSG00000145386 PMC6610925__F3 Hexosamine extended and salvage pathways ENSG00000159921 ENSG00000147162 ENSG00000198408 ENSG00000124357 PMC6610925__F4 HBP regulates multiple proteins in cancer cells via OGT ENSG00000188486 ENSG00000147162 ENSG00000198793 PMC8457844__F2 Classically known renin angiotensin pathway and the inhibitors identified from our high throughput screen ENSG00000180772 PMC8571027__F4 Arginine methylation negatively regulates the anti-viral response ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000163565 ENSG00000132600 ENSG00000198890 PMC5084027__F4 AMP-activated protein kinase (AMPK) signaling pathway ENSG00000104812 ENSG00000171105 ENSG00000141556 ENSG00000291971 ENSG00000288174 ENSG00000198793 ENSG00000284161 ENSG00000113161 ENSG00000167658 ENSG00000103150 ENSG00000169710 ENSG00000141564 ENSG00000157184 ENSG00000001626 ENSG00000079435 PMC6794370__F7 Mitochondrial dynamics in cancer ENSG00000284495 ENSG00000100335 ENSG00000168958 ENSG00000116688 ENSG00000171109 ENSG00000214253 PMC6794370__F2 Mitochondrial physiology ENSG00000182511 PMC9439649__F4 CAR T-Cell Therapy for Patients with Multiple Myeloma: Current Evidence and Challenges ENSG00000002330 ENSG00000198793 ENSG00000171791 ENSG00000081189 PMC12124620__F4 A) The role of notch signaling pathway in the aging of MSCs ENSG00000114315 PMC9526582__F2 Identification of Novel miRNAs, Targeting Genes, Signaling Pathway, and the Small Molecule for Overcoming Oxaliplatin Resistance of Metastatic Colorectal Cancer ENSG00000163618 ENSG00000187720 ENSG00000163737 ENSG00000115457 ENSG00000147044 ENSG00000196406 ENSG00000186603 ENSG00000091972 ENSG00000162551 ENSG00000075945 ENSG00000197632 ENSG00000123096 ENSG00000129226 ENSG00000058091 ENSG00000021645 ENSG00000103888 ENSG00000281123 ENSG00000164484 ENSG00000160183 ENSG00000120669 ENSG00000292187 ENSG00000188219 ENSG00000160180 ENSG00000010810 ENSG00000023839 PMC4592163__F1 Endoplasmic reticulum stress inducing autophagy ENSG00000128272 ENSG00000144895 PMC6098222__F2 Stimuli-induced TLR2- and NOD2- mediated signaling ENSG00000226275 ENSG00000167207 ENSG00000172005 ENSG00000172936 ENSG00000150455 ENSG00000175104 PMC2715236__F6 Model for the role of FANCM in the DNA damage response ENSG00000131944 ENSG00000144554 ENSG00000187790 PMC5385391__F9 HMGB1 release regulated by the PLCG1–IP3R–SOC signalling pathway during calcium overload in hepatocytes ENSG00000167323 ENSG00000293604 ENSG00000189403 PMC9537025__F1 Mass spectrometry-based approaches to explore metabolism regulating ferroptosis ENSG00000167468 ENSG00000111684 ENSG00000102967 PMC4047366__F11 Metabolic feedback via HBP and N-glycan branching ENSG00000288269 ENSG00000131446 ENSG00000168282 ENSG00000152127 PMC8889000__F3 Autophagy: a multifaceted player in the fate of sperm ENSG00000100151 ENSG00000157404 ENSG00000174903 ENSG00000152661 ENSG00000109083 ENSG00000188425 ENSG00000096717 ENSG00000047932 PMC7500163__F1 Pathways expressed during humoral immune response of SARS-CoV-2 infection ENSG00000128272 ENSG00000049130 ENSG00000100906 ENSG00000100985 ENSG00000112715 ENSG00000121060 ENSG00000150630 PMC7017144__F10 Pathway signaling network generated from the genes located within the top 100 DM tiling regions ENSG00000138639 ENSG00000070831 ENSG00000169862 ENSG00000105550 ENSG00000291971 ENSG00000168036 ENSG00000140044 ENSG00000101266 ENSG00000158445 ENSG00000089159 ENSG00000104368 ENSG00000122691 ENSG00000168310 ENSG00000177084 ENSG00000151914 ENSG00000065361 ENSG00000067900 ENSG00000164120 ENSG00000149311 ENSG00000099889 ENSG00000100749 ENSG00000115415 ENSG00000170604 ENSG00000146592 ENSG00000070770 ENSG00000168264 ENSG00000019549 ENSG00000145743 ENSG00000112851 ENSG00000173846 ENSG00000130669 ENSG00000178568 ENSG00000132341 PMC3715061__F1 Hedgehog signaling, vismodegib action, and acquired resistance ENSG00000106571 ENSG00000117425 ENSG00000128602 PMC8652134__F3 Notch Signaling Pathway in Non-Alcoholic Fatty Liver Disease ENSG00000042832 ENSG00000148400 ENSG00000124253 PMC5568783__F2 PERK arm of the unfolded protein response ENSG00000144895 ENSG00000100219 ENSG00000171791 PMC4051800__F6 Causal BN learned from breast cancer cases for the ErbB pathway ENSG00000002330 ENSG00000291971 ENSG00000138798 ENSG00000050748 ENSG00000115904 ENSG00000105647 ENSG00000142273 ENSG00000099942 ENSG00000100485 ENSG00000121879 ENSG00000148082 ENSG00000129946 ENSG00000149269 ENSG00000136997 ENSG00000071051 ENSG00000197943 ENSG00000124181 ENSG00000157764 ENSG00000065361 ENSG00000109321 ENSG00000113070 ENSG00000158458 ENSG00000169752 ENSG00000187840 ENSG00000117020 ENSG00000110395 ENSG00000148660 ENSG00000163235 ENSG00000124882 ENSG00000177606 ENSG00000143322 ENSG00000146648 ENSG00000145349 ENSG00000178568 PMC2100400__F2 Innate and Adaptive Immune Response to Apoptotic Cells ENSG00000173599 ENSG00000140545 ENSG00000132693 PMC5568783__F1 IRE1A arm of the unfolded protein response ENSG00000162711 ENSG00000132478 ENSG00000265972 ENSG00000100219 PMC3735949__F3 Comparison of gene expression in RAW264.7 (RAW) and TGEM cells treated with KLA for the TLR4 signaling pathway ENSG00000104856 ENSG00000243414 ENSG00000171855 ENSG00000282905 ENSG00000169032 ENSG00000150455 ENSG00000135341 ENSG00000183735 ENSG00000090376 ENSG00000064012 ENSG00000104365 ENSG00000115008 ENSG00000154589 ENSG00000137275 ENSG00000269335 ENSG00000173039 ENSG00000162924 ENSG00000168040 ENSG00000127666 ENSG00000073756 ENSG00000276561 ENSG00000007171 ENSG00000170458 ENSG00000118503 ENSG00000141086 ENSG00000172005 ENSG00000131323 ENSG00000162692 ENSG00000184216 PMC3983408__F7 Mechanism of immune dysfunction in Huntington’s disease ENSG00000184216 PMC3887194__F13 Schematic modeling of the TcpB inhibition of TLR4 signaling ENSG00000172005 ENSG00000172936 ENSG00000136869 PMC5762524__F3 Differences in the expression of long noncoding RNAs at different time points in the PTSD-like syndrome rat hippocampus ENSG00000087095 ENSG00000172680 ENSG00000170458 ENSG00000177606 ENSG00000130159 ENSG00000175104 ENSG00000127191 ENSG00000146648 ENSG00000081189 ENSG00000026103 PMC6378226__F1 Cell death pathways currently implicated in motor neuron cell death in ALS and related miRNAs ENSG00000132906 ENSG00000168040 ENSG00000168404 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC4031100__F3 Nutritional metabolomics: Progress in addressing complexity in diet and health ENSG00000004864 ENSG00000172005 ENSG00000111181 ENSG00000254550 PMC10453317__F2 GAB1 recruitment modes to activated receptors and major GAB1 signaling pathways PMC4292994__F3 Host genes with reproducible microbiome associations across cohorts ENSG00000110944 ENSG00000112977 ENSG00000167207 ENSG00000269335 ENSG00000074966 ENSG00000113302 ENSG00000168811 ENSG00000168610 PMC4630209__F2 KIT-mediated signaling events ENSG00000157404 ENSG00000033327 ENSG00000010810 ENSG00000010671 PMC8166497__F5 N-trans-Feruloyloctopamine Wakes Up BBC3, DDIT3, CDKN1A, and NOXA Signals to Accelerate HCC Cell Apoptosis ENSG00000178573 ENSG00000135116 PMC11077654__S1 Cerebrospinal Fluid Dysregulation via a SPAK and OSR1 Targeted Framework Nucleic Acid in Hydrocephalus ENSG00000143867 ENSG00000184371 PMC4890577__F1 Bile acid signaling in murine hepatocytes ENSG00000267534 PMC8166497__F4 N-trans-Feruloyloctopamine Wakes Up BBC3, DDIT3, CDKN1A, and NOXA Signals to Accelerate HCC Cell Apoptosis ENSG00000142192 ENSG00000010671 ENSG00000291368 PMC312639__F9 Proposed model for RhoA signaling to the c-jun promoter ENSG00000070831 ENSG00000163914 PMC4079737__F1 Molecular Pathways: Niches in Metastatic Dormancy ENSG00000167601 ENSG00000171791 ENSG00000204217 PMC7285711__F3 Interaction network analysis of the (A) visceral obesity pathway and (B) the cell cycle pathway, using the path designer of IPA ENSG00000198176 ENSG00000054118 ENSG00000168779 ENSG00000139687 ENSG00000134480 PMC5452017__F2 Brain metabolism in health, aging, and neurodegeneration ENSG00000180210 ENSG00000134982 PMC5115734__F5 Evolution of the Tetrapyrrole Biosynthetic Pathway in Secondary Algae: Conservation, Redundancy and Replacement ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000188690 PMC5452017__F3 Brain metabolism in health, aging, and neurodegeneration ENSG00000131473 ENSG00000112972 PMC9285394__F6 Vascular smooth muscle cells in the development of aortic aneurysms and dissections ENSG00000185532 ENSG00000166147 PMC5452017__F5 Brain metabolism in health, aging, and neurodegeneration ENSG00000142082 ENSG00000106459 PMC9645596__F1 TGFB: Signaling Blockade for Cancer Immunotherapy ENSG00000135655 ENSG00000102226 ENSG00000198742 ENSG00000163914 ENSG00000175104 ENSG00000076604 PMC3812160__F7 Transcriptome-Wide Mapping of Pea Seed Ageing Reveals a Pivotal Role for Genes Related to Oxidative Stress and Programmed Cell Death ENSG00000150991 ENSG00000148356 ENSG00000105227 PMC3693914__F2 DA biosynthesis and degradation PMC524522__F9 Mapping molecular correlates of aggressive mesothelioma to highly curated molecular pathways can identify the underlying molecular mechanisms of the disease ENSG00000196839 ENSG00000159388 PMC9433080__F1 Treating non-small cell lung cancer by targeting the PI3K signaling pathway ENSG00000132906 ENSG00000002330 ENSG00000150907 ENSG00000163914 ENSG00000051180 ENSG00000149554 PMC3792429__F1 Hierarchy of nucleolar stress-induced neuroprotection ENSG00000198793 PMC4227423__F2 Differentially expressed genes in the proteasome pathway ENSG00000153487 ENSG00000132383 ENSG00000291973 ENSG00000132963 ENSG00000062485 PMC4111284__F1 IGF signaling pathway ENSG00000197081 ENSG00000291972 ENSG00000112964 ENSG00000157005 ENSG00000140443 PMC6700399__F1 Inflammatory pathway centered upon TNF in the process of NASH-HCC development ENSG00000115415 ENSG00000136869 ENSG00000047936 ENSG00000168610 PMC6023281__F3 Neuroprotection and the PI3K/AKT/PTEN/GSK-3B pathway and SODs ENSG00000178573 PMC5801575__F5 Proposed biosynthetic pathways of Cat315+, Cat316+ and WFA+ aggrecan ENSG00000069482 ENSG00000062485 PMC7886076__F4 PTEN signalling in other major oncogenic pathways ENSG00000140564 ENSG00000170965 ENSG00000168036 PMC3735949__F4 Comparison of the gene expression and eicosanoid metabolite changes in RAW264.7 (RAW) and TGEM cells treated with KLA is shown for the arachidonic acid metabolism pathway ENSG00000184381 ENSG00000243708 ENSG00000141086 ENSG00000095303 ENSG00000148344 ENSG00000275565 ENSG00000073756 ENSG00000127472 PMC2768990__F2 BANs of differentially expressed genes in common between cell lines ENSG00000228716 ENSG00000089356 ENSG00000101670 ENSG00000145687 ENSG00000163565 ENSG00000139278 ENSG00000155850 PMC3735949__F5 A comparison of gene expression and lipid metabolite changes in RAW264.7 (RAW) and TGEM cells treated with KLA is shown for the sterol biosynthesis pathway ENSG00000138135 ENSG00000116133 ENSG00000172893 ENSG00000141086 ENSG00000109929 ENSG00000113161 ENSG00000104549 ENSG00000167780 PMC5801404__F2 Mechanistic map of the signaling pathways involved in local translation mediated by class I mGluRs in neurons ENSG00000274588 ENSG00000198793 ENSG00000173599 ENSG00000284161 ENSG00000198576 ENSG00000155974 PMC9152184__F2 Update in TIGIT Immune-Checkpoint Role in Cancer ENSG00000181847 ENSG00000137265 ENSG00000107485 ENSG00000049768 ENSG00000150637 PMC3735949__F6 Changes in the genes and processes related to mitochondrial metabolism in RAW264.7 and TGEM cells treated with KLA ENSG00000157184 ENSG00000125246 ENSG00000026103 PMC198547__F8 Leptin action on the TRH neuron ENSG00000115138 ENSG00000166603 ENSG00000168610 PMC2908768__F4 Cytokine signaling through the Jak/Stat pathway in mammary gland development ENSG00000288411 ENSG00000145623 ENSG00000099985 ENSG00000113520 PMC11655924__F3 High glucose in diabetes enhances Wnt-stimulated nuclear accumulation of Beta-catenin ENSG00000138795 ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3092522__F1 HER2-amplified breast cancer: mechanisms of trastuzumab resistance and novel targeted therapies ENSG00000198793 ENSG00000140443 PMC11655924__F1 Anomaly of the insulin-signaling pathway ENSG00000169291 ENSG00000169047 ENSG00000198793 ENSG00000115904 PMC5663718__F3 Periodontitis caused by defective killing of bacteria ENSG00000108691 ENSG00000122194 PMC11655924__F2 Adrenergic signaling at the crossroads of diabetes, obesity, and cancer ENSG00000169047 ENSG00000173334 PMC6060254__F1 lncRNAs involved in the IFN antiviral response ENSG00000213928 ENSG00000117228 ENSG00000187608 ENSG00000089127 ENSG00000157601 ENSG00000185745 ENSG00000185885 ENSG00000276561 ENSG00000184979 ENSG00000183735 ENSG00000134321 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000134326 ENSG00000135114 ENSG00000172936 ENSG00000142089 ENSG00000164342 PMC8034148__F2 Regulatory mechanism of necroptosis ENSG00000137275 ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC7237193__F7 Regulatory network of let-7 is associated with the metabolism of glucose, fatty acids and amino acids in the silk gland ENSG00000173599 PMC9502527__F2 Molecular Pathways of WRKY Genes in Regulating Plant Salinity Tolerance ENSG00000167941 ENSG00000136997 PMC11703377__F1 Remodeled fatty acid metabolism in tumor cells ENSG00000131473 ENSG00000134086 ENSG00000198793 ENSG00000169710 ENSG00000099194 ENSG00000146648 PMC8222901__F2 Emerging Roles of MHC Class I Region-Encoded E3 Ubiquitin Ligases in Innate Immunity ENSG00000162711 ENSG00000167207 ENSG00000112343 ENSG00000102871 ENSG00000105298 ENSG00000127191 ENSG00000183735 ENSG00000088888 ENSG00000082512 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC3078523__F2 Heme Oxygenase-1, a Critical Arbitrator of Cell Death Pathways in Lung Injury and Disease ENSG00000002330 PMC3953959__F6 Regulation of TFs activity by degradation modulated by H2O2 ENSG00000149311 ENSG00000079999 PMC7248300__F2 HCMV encoded proteins which help to evade CD4+ T cell mediated immune responses ENSG00000164430 PMC9507777__F4 Single-Cell Transcriptome Analysis Reveals Different Immune Signatures in HPV- and HPV + Driven Human Head and Neck Squamous Cell Carcinoma PMC4941299__F8 Involvement of SULF2 in Gamma-irradiation-induced invasion and resistance of cancer cells by inducing IL-6 expression ENSG00000168036 ENSG00000196562 ENSG00000168610 PMC8120474__F8 Accelerated Bone Regeneration by Astragaloside IV through Stimulating the Coupling of Osteogenesis and Angiogenesis ENSG00000168036 ENSG00000131196 PMC5437908__F2 Predicted synthesis pathway for the t6A modification and its derivatives in H ENSG00000275619 ENSG00000136932 ENSG00000196449 ENSG00000145996 PMC5911724__F5 PI3K–AKT signaling pathway ENSG00000104812 ENSG00000140992 ENSG00000002330 ENSG00000105401 ENSG00000169047 ENSG00000134308 ENSG00000214827 ENSG00000167393 ENSG00000171791 ENSG00000169032 ENSG00000012048 ENSG00000177455 ENSG00000103479 ENSG00000136997 ENSG00000132906 ENSG00000119535 ENSG00000109320 ENSG00000108342 ENSG00000213341 ENSG00000107175 ENSG00000160741 ENSG00000117020 ENSG00000040199 ENSG00000124253 ENSG00000155629 ENSG00000069966 PMC6908429__F4 Tetherin blocks virus release, activates an innate immune response and is counteracted by Vpu or Nef ENSG00000169245 ENSG00000175104 ENSG00000127191 PMC7582160__F4 Details of unfolded protein response activation in the venom gland ENSG00000085117 ENSG00000159461 ENSG00000186480 ENSG00000165280 ENSG00000140943 ENSG00000127022 ENSG00000115816 ENSG00000171791 ENSG00000012174 ENSG00000127191 ENSG00000135506 ENSG00000162298 ENSG00000132170 ENSG00000178607 ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000069345 ENSG00000198911 PMC4325158__F3 Transcriptomic changes in central metabolic pathways induced by pho13Δ during growth on different carbon sources ENSG00000074800 PMC6509240__F7 Working model of polyI:C-mediated protection on pancreases from inflammatory injuries ENSG00000081041 ENSG00000163739 ENSG00000125538 PMC11669671__F3 Genome mining and biosynthetic pathways of marine-derived fungal bioactive natural products ENSG00000140263 ENSG00000285200 PMC7465096__F8 “cooperativity model of MIP-1A amplification” in THP-1 monocytic cells ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC10389819__F6 C-Phycocyanin Ameliorates the Senescence of Mesenchymal Stem Cells through ZDHHC5-Mediated Autophagy via PI3K/AKT/mTOR Pathway ENSG00000178860 ENSG00000198793 ENSG00000156599 PMC11669671__F6 BGCs and biosynthetic pathways of (A) amphichopyrone B (39) and (B) penilactone A (41) and B (42) ENSG00000100473 ENSG00000078053 PMC7550695__F1 Molecular players involved in the NRF1 pathway ENSG00000135655 ENSG00000147162 ENSG00000151092 ENSG00000106459 PMC6854591__F8 PH-EPS modulates the activation of RAW264.7 cells through the TLR4(Dectin-1)/NFKB/MAPK pathway ENSG00000172936 ENSG00000150455 PMC10531730__F1 Depiction of Branched-Chain Amino Acids (BCAAs) in Diabetes with a Focus on Diabetic Microvascular Complications ENSG00000169047 PMC5085738__F4 Schematic model of drought responsive proteins involved in photosynthesis, carbon metabolism, fatty acid metabolism, and nitrogen and amino acid metabolism ENSG00000261701 ENSG00000197713 ENSG00000173599 ENSG00000172482 ENSG00000145020 ENSG00000062485 PMC6755737__F1 The central carbon metabolism of C ENSG00000150787 PMC10741690__F2 Mitophagy pathway ENSG00000110497 ENSG00000123240 ENSG00000158828 ENSG00000069509 PMC11844033__F8 Graphical Abstract Under hypoxic conditions, JUN enhances the transcription of EGLN3, which subsequently binds to HUR to positively regulate the stability of EGFR mRNA ENSG00000177606 ENSG00000146648 PMC5930795__F5 Dietary and Endocrine Regulation of Endogenous Hydrogen Sulfide Production: Implications for Longevity ENSG00000128272 ENSG00000291972 ENSG00000105550 ENSG00000169047 ENSG00000170893 ENSG00000282891 PMC6856370__F9 Model of cross-talk between D2R and Wnt/Beta-catenin pathways, and Wnt3a transcriptional regulation ENSG00000154342 ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC8708225__F1 Activation of the Hippo Pathway in Rana sylvatica: Yapping Stops in Response to Anoxia ENSG00000150457 ENSG00000131023 PMC7366106__F8 TNF pathway modified from hsa04668 ENSG00000149968 ENSG00000078747 ENSG00000102871 ENSG00000007908 ENSG00000166278 ENSG00000131323 ENSG00000128342 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000164305 PMC9523645__F7 SARS-CoV-2 Nsp6-mediated disruption of glycolysis ENSG00000156374 ENSG00000198176 ENSG00000136997 ENSG00000213614 ENSG00000174197 PMC5590720__F1 Modes of action of Abatacept/Belatacept and anti-CD28 domain antibodies ENSG00000134982 PMC4950965__F2 Targeting the RB-E2F pathway in breast cancer ENSG00000135446 ENSG00000136997 ENSG00000105810 PMC3887071__F2 Synthesis and Biological Properties of Fungal Glucosylceramide ENSG00000039537 ENSG00000113600 PMC2680291__F1 Illustration of some of the key enzymes involved in the metabolism of methotrexate (MTX) ENSG00000228716 ENSG00000173638 ENSG00000136877 ENSG00000137563 ENSG00000118777 PMC3566151__F1 TGFB and TGFB/Smad Signaling in the Interactions between Echinococcus multilocularis and Its Hosts PMC7116212__F6 Ribosome biogenesis pathway showing genes which are significantly changing upon sodium azide treatment of wild type cells ENSG00000101751 ENSG00000177971 ENSG00000145912 ENSG00000070814 ENSG00000241945 ENSG00000130826 ENSG00000262788 ENSG00000109534 ENSG00000136718 ENSG00000291996 ENSG00000011260 ENSG00000101361 ENSG00000169251 ENSG00000041802 ENSG00000126749 ENSG00000185721 ENSG00000108651 ENSG00000164338 ENSG00000165733 ENSG00000141101 ENSG00000055044 ENSG00000132341 PMC9500434__F8 Fucoxanthin prevents breast cancer metastasis by interrupting circulating tumor cells adhesion and transendothelial migration ENSG00000170558 ENSG00000168036 ENSG00000162692 PMC6844627__F4 Mapping Biological Networks from Quantitative Data-Independent Acquisition Mass Spectrometry Proteomic Data: Data to Knowledge Pipelines ENSG00000122367 ENSG00000150991 ENSG00000108515 ENSG00000108861 PMC8908968__F2 Genetics and Epigenetics of Parathyroid Carcinoma ENSG00000134371 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000155011 ENSG00000168036 ENSG00000168646 PMC4451040__F2 Back from the dead; the curious tale of the predatory cyanobacterium Vampirovibrio chlorellavorus ENSG00000039537 ENSG00000134982 ENSG00000197429 ENSG00000181026 ENSG00000062485 PMC4023818__F10 Working model ENSG00000179094 PMC7357070__F3 Toll-like receptor signaling pathway includes the highest number of the proteins identified, related to immune system pathways and appearing in both SARS-CoV-2 and HIV-1 infections ENSG00000239732 ENSG00000144410 ENSG00000170458 ENSG00000168040 ENSG00000150455 ENSG00000143387 PMC12076214__F3 Multifunctional cytochrome P450 orchestrates radical cleavage and non-radical cyclization in 5-oxaindolizidine biosynthesis† ENSG00000166278 ENSG00000167182 PMC8115730__F2 Mechanisms controlling pancreatic islet cell function in insulin secretion ENSG00000131473 ENSG00000079387 ENSG00000173599 ENSG00000079432 PMC3262193__F3 Signaling pathways and proteins that increase or decrease STAT5 signaling in normal mammary epithelial cells ENSG00000163235 ENSG00000149269 ENSG00000138798 ENSG00000178568 PMC10706414__F1 Interleukin (IL)-37 maintains its anti-inflammatory outcomes by limiting IL-18RA from adhering to IL-18 and by attracting the orphan decoy IL-1R8 to the IL-18R/IL-37/IL-1R8 complex ENSG00000162711 ENSG00000010810 ENSG00000198793 ENSG00000172936 ENSG00000168610 PMC7817290__F1 The effects of hypoxia on BMSC senescence ENSG00000198793 PMC8614808__F4 TRAP1 in Oxidative Stress and Neurodegeneration ENSG00000128272 ENSG00000144895 ENSG00000170558 ENSG00000168610 PMC8505617__F6 The TGFB signaling pathway and the interaction between lncRNAs and the pathway PMC8505617__F5 The Hedgehog signaling pathway and the interactions between lncRNAs and the pathway ENSG00000143147 ENSG00000128602 PMC3995050__F1 The PI3K/Akt/mTOR pathway ENSG00000002330 ENSG00000005882 ENSG00000198793 ENSG00000164327 PMC8326207__SF2 Lipidomic and transcriptional analysis of the linoleoyl-omega-hydroxyceramide biosynthetic pathway in human psoriatic lesions ENSG00000170426 ENSG00000171954 ENSG00000042832 ENSG00000154227 ENSG00000105131 ENSG00000015285 PMC8505641__F4 Mechanisms involved in the modulation of inflammation by miRNA derived EVs ENSG00000162711 ENSG00000291971 ENSG00000172936 ENSG00000168610 ENSG00000184216 PMC4943346__F1 Destruction complex of beta-catenin in colorectal carcinoma and colonic adenoma ENSG00000134982 ENSG00000168036 PMC5655313__F4 Role of growth differentiation factor 11 in development, physiology and disease ENSG00000127578 ENSG00000070404 ENSG00000135414 PMC8218521__F1 Systems glycobiology for discovering drug targets, biomarkers, and rational designs for glyco-immunotherapy ENSG00000177455 ENSG00000069482 PMC8218521__F2 Systems glycobiology for discovering drug targets, biomarkers, and rational designs for glyco-immunotherapy ENSG00000000419 ENSG00000164414 ENSG00000131446 ENSG00000170191 ENSG00000173540 ENSG00000111726 ENSG00000198380 ENSG00000168282 ENSG00000205060 ENSG00000152127 ENSG00000157353 ENSG00000100170 ENSG00000112699 ENSG00000214160 ENSG00000135452 ENSG00000136908 ENSG00000100417 ENSG00000112893 ENSG00000292209 ENSG00000013375 ENSG00000101901 ENSG00000109814 ENSG00000159921 ENSG00000069482 ENSG00000124357 ENSG00000117620 ENSG00000159399 PMC9169372__F7 Targeting type IG phosphatidylinositol phosphate kinase overcomes oxaliplatin resistance in colorectal cancer ENSG00000012048 PMC6397541__F7 AhR−AREG axis defines a signaling pathway between cellular intrinsic redox mechanisms and surrounding TME ENSG00000108691 ENSG00000081041 ENSG00000109321 ENSG00000163739 ENSG00000112715 ENSG00000146648 ENSG00000106546 PMC8699227__F7 Cell Cycle Progression by Growth Factor-Induced Cell Signaling ENSG00000135446 PMC8699227__F8 Cell Cycle Progression by Growth Factor-Induced Cell Signaling ENSG00000002330 PMC11659109__F3 Triggers for postnatal metabolic shift ENSG00000175567 PMC4357026__F8 Diagram depicting the possible activation of TM detoxification of xenobiotics ENSG00000170458 ENSG00000136869 PMC3762301__F3 Molecular inhibitory mechanism of cPAP to block proliferation and survival of prostate cells ENSG00000187837 PMC3739039__F3 Integrated “omic” analysis reveals global metabolic changes PMC12205135__F3 Molecular mechanisms of peripheral sensitization in cancer pain ENSG00000108691 ENSG00000168398 ENSG00000100739 ENSG00000196689 PMC12205135__F5 Glia-neuron interplay drives central sensitization in cancer pain ENSG00000107562 ENSG00000163739 ENSG00000121966 PMC9490723__F1 Proviral role of caspase-6 ENSG00000088888 ENSG00000128272 ENSG00000144895 ENSG00000276561 PMC6335100__F2 Mechanistic target of rapamycin (mTOR) signaling network ENSG00000177169 ENSG00000128272 ENSG00000177058 ENSG00000169047 ENSG00000112561 ENSG00000239282 ENSG00000196712 PMC4636073__F7 T cell receptor signaling pathway showing downstream mediators regulated by DNA methylation, gene/protein expression and/or protein phosphorylation ENSG00000140992 ENSG00000151490 ENSG00000291603 ENSG00000282905 ENSG00000070831 ENSG00000050748 ENSG00000163599 ENSG00000115904 ENSG00000169032 ENSG00000135341 ENSG00000141968 ENSG00000213658 ENSG00000149269 ENSG00000071051 ENSG00000113520 ENSG00000113263 ENSG00000124181 ENSG00000113525 ENSG00000198286 ENSG00000104365 ENSG00000100906 ENSG00000109320 ENSG00000198851 ENSG00000269335 ENSG00000173039 ENSG00000213341 ENSG00000043462 ENSG00000006062 ENSG00000188389 ENSG00000111537 ENSG00000110395 ENSG00000135446 ENSG00000010810 ENSG00000177606 ENSG00000131196 PMC5216784__F10 Methamphetamine-mediated endoplasmic reticulum (ER) stress induces type-1 programmed cell death in astrocytes via ATF6, IRE1A and PERK pathways ENSG00000128272 ENSG00000100219 PMC8262610__F2 Fc Gamma Receptors as Regulators of Bone Destruction in Inflammatory Arthritis ENSG00000170909 ENSG00000175104 ENSG00000131196 ENSG00000135605 ENSG00000010671 PMC5334358__F1 Necrototic pathway ENSG00000102871 ENSG00000163220 ENSG00000082512 ENSG00000189403 ENSG00000083799 ENSG00000168040 ENSG00000127191 PMC9277014__F1 Roles of TNF Signaling Pathways in Metabolism of Bone Tumors ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC5343756__F1 A Critical Evaluation of Neuroprotective and Neurodegenerative MicroRNAs in Alzheimer’s Disease ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC6770144__F1 HER2 signaling pathway ENSG00000135446 ENSG00000198793 ENSG00000177606 ENSG00000136997 ENSG00000123374 ENSG00000105810 PMC6770144__F2 Mechanism of TRA/GO action ENSG00000102871 ENSG00000082512 ENSG00000168040 ENSG00000168404 ENSG00000127191 PMC8002821__F3 Classical NFKB (Right) and STAT3 (left) activation pathways ENSG00000019991 ENSG00000198793 ENSG00000173039 ENSG00000132478 ENSG00000131323 ENSG00000127191 ENSG00000168610 PMC12089637__F7 Proposed mechanism of LRRC56 regulation BC progression via RhoA/ROCKs axis ENSG00000273831 PMC7792434__F1 IL-39 and signaling pathway ENSG00000162594 ENSG00000115415 ENSG00000105246 ENSG00000168610 PMC3579806__F4 Differentially Expressed miRNAs after GnRH Treatment and Their Potential Roles in FSH Regulation in Porcine Anterior Pituitary Cell ENSG00000109163 ENSG00000087245 ENSG00000070831 ENSG00000291971 ENSG00000157227 ENSG00000138798 ENSG00000146648 PMC6125400__F4 Simplified KEGG pathway “Proteoglycans in Cancer” with H3K4me3 and H3K27me3 enriched genes ENSG00000011422 ENSG00000136997 ENSG00000141639 ENSG00000196914 ENSG00000047849 PMC9166240__F6 Targeting protein phosphatases for the treatment of inflammation-related diseases: From signaling to therapy ENSG00000262406 ENSG00000033327 ENSG00000291603 ENSG00000198793 ENSG00000168610 PMC11745089__F2 Relationships between gut microbiota, gut microbiota-associated metabolites, and EGFR/VEGFR/KRAS pathways ENSG00000138798 ENSG00000198793 ENSG00000185591 ENSG00000146648 PMC9166240__F8 Targeting protein phosphatases for the treatment of inflammation-related diseases: From signaling to therapy ENSG00000172936 ENSG00000168610 PMC9011113__F3 Myth of cobra venom cytotoxin: More than just direct cytolytic actions ENSG00000086991 ENSG00000164305 ENSG00000026103 PMC2707240__F2 Proposed model for As2O3-dependent activation of the mTOR pathway in a negative feedback regulatory manner in malignant cells ENSG00000198793 PMC3466441__F1 Peptide neuromodulation in invertebrate model systems ENSG00000163064 ENSG00000258429 ENSG00000164778 PMC6244318__F1 KEGG insulin signaling pathway identified by WebGestalt from the bta-miR-486 target gene list ENSG00000171105 ENSG00000002330 ENSG00000150907 ENSG00000026103 PMC6617290__F1 Model that proposes the form in which physical activity activates the nuclear factor erythroid 2-related factor 2 (Nrf2)–Keap1 pathway ENSG00000178573 ENSG00000079999 PMC7140412__F2 The autophagy molecular pathway and target steps of its modulation ENSG00000110497 ENSG00000198382 ENSG00000083290 ENSG00000126775 ENSG00000150907 ENSG00000198793 ENSG00000144848 ENSG00000145782 PMC6617290__F2 Antioxidant and Adaptative Response Mediated by Nrf2 during Physical Exercise ENSG00000198793 ENSG00000284161 ENSG00000096717 ENSG00000106459 PMC4111995__F2 Molecular insights into NF2/Merlin tumor suppressor function ENSG00000126016 ENSG00000150457 ENSG00000131023 ENSG00000072415 PMC8115215__F8 PSA regulatory mechanism of VRC metabolism ENSG00000165841 ENSG00000125538 ENSG00000172936 ENSG00000175104 PMC4356644__F1 BiP and its Nucleotide Exchange Factors Grp170 and Sil1: Mechanisms of Action and Biological Functions PMC5732750__F6 CXXC4 activates apoptosis through up-regulating GDF15 in gastric cancer ENSG00000185591 ENSG00000168772 ENSG00000130513 PMC2953915__F7 Model of E2F2-mediated regulation of the Ahr pathway ENSG00000110711 ENSG00000276787 ENSG00000282899 ENSG00000106546 PMC8505617__F1 The canonical Wnt/Beta-catenin signaling pathway and the interactions between lncRNAs and the pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC2667932__F1 Model for TGFB1-induced PAI-1 expression ENSG00000163914 ENSG00000146648 PMC9456094__F2 PTPN2 in the Immunity and Tumor Immunotherapy: A Concise Review PMC6313860__F2 CLV-WUS signaling pathways in model and crop plant meristems ENSG00000090402 PMC3794713__F1 Simplified overview of commonly mutated oncogenes, tumor suppressors, and pathways in endocrine cancer ENSG00000135956 ENSG00000134086 ENSG00000157764 ENSG00000136997 ENSG00000196712 PMC5217521__F2 Oncogenic mutations for the upregulation of EREG expression.Notes: Oncogenic mutations in the EGFR, KRAS, or BRAF genes result in activation of the MEK/ERK signaling pathway, which in turn upregulates EREG expression ENSG00000157764 ENSG00000124882 ENSG00000178568 PMC6812587__F2 Macrophage function by polyamine synthesis ENSG00000081181 ENSG00000088826 ENSG00000118520 ENSG00000116649 ENSG00000102172 ENSG00000057663 ENSG00000007171 PMC6755139__F3 STRING connectivity network demonstrating a protein–protein interaction network of predicted functional partners for differentially expressed genes in the brown module ENSG00000123240 ENSG00000070831 ENSG00000066926 ENSG00000156482 ENSG00000101782 ENSG00000118777 ENSG00000135924 ENSG00000111726 ENSG00000106327 ENSG00000178573 ENSG00000073792 ENSG00000136908 ENSG00000146007 ENSG00000134779 ENSG00000152484 ENSG00000198876 ENSG00000138346 ENSG00000115993 ENSG00000140264 ENSG00000063854 ENSG00000103510 ENSG00000173598 ENSG00000156467 ENSG00000154813 ENSG00000161970 ENSG00000153574 ENSG00000166947 ENSG00000274145 ENSG00000184470 ENSG00000102760 ENSG00000028528 ENSG00000088992 PMC4853920__F3 Alternative pathway is constitutively active at low levels through the hydrolysis of the thioester in C3 to C3(H2O) ENSG00000039537 PMC4703717__F1 Synthesis and immunomodulatory effect of gangliosides ENSG00000069482 ENSG00000111728 PMC1237076__F7 Wnt-NLK pathway inhibits the activity of Myb family of proteins by two different mechanisms ENSG00000087095 ENSG00000064393 ENSG00000125084 PMC10946266__F6 MgH2 protects against APAP-AKI by inhibiting TXNIP/NLRP3/NFKB pathway ENSG00000162711 ENSG00000002330 PMC2699768__F3 Aryl hydrocarbon receptor (AhR) pathway as a regulatory pathway for cell adhesion and matrix metabolism ENSG00000049323 ENSG00000185591 ENSG00000122194 ENSG00000106546 PMC5359838__F5 Schematic representation of the opposite p53-TRIM8 and N-MYC-miR17-5p/miR106b-5p networks in cellular response to treatments ENSG00000171206 PMC2699768__F1 Aryl hydrocarbon receptor (AhR) pathway as a regulatory pathway for cell adhesion and matrix metabolism ENSG00000168036 ENSG00000146648 PMC6888570__F2 Canonical KEAP1/NFE2L2 antioxidant signalling pathway, induced by electrophilic ligands ENSG00000116044 ENSG00000100387 ENSG00000079999 PMC4584279__F3 Selected signal networks induced by Dectin-1 and Dectin-2 ENSG00000104856 ENSG00000187796 ENSG00000173599 ENSG00000122877 ENSG00000197943 ENSG00000115009 PMC4317086__F1 Figure can be read from the upper-left corner in an anti-clockwise direction PMC2677203__F7 Signaling via the TgfB type I receptor Alk5 in heart development ENSG00000168036 ENSG00000131196 PMC10970480__F3 Potential mechanisms by which exercise intervenes in insulin resistance through mitochondria-associated membranes ENSG00000042832 ENSG00000116688 ENSG00000156026 ENSG00000069509 ENSG00000214253 PMC7340521__F7 Dual RNA-seq provides novel insight into the roles of dksA from Pseudomonas plecoglossicida in pathogen-host interactions with large yellow croakers (Larimichthys crocea) ENSG00000167207 ENSG00000102871 ENSG00000163739 ENSG00000157227 ENSG00000149968 ENSG00000078747 ENSG00000056558 ENSG00000163734 ENSG00000164400 ENSG00000157625 ENSG00000128342 ENSG00000168404 ENSG00000064012 ENSG00000026103 ENSG00000081041 ENSG00000007908 ENSG00000168040 ENSG00000127191 ENSG00000169245 ENSG00000226275 ENSG00000118503 ENSG00000164136 ENSG00000184371 ENSG00000131323 ENSG00000100985 PMC10970480__F2 Lipid metabolism-related proteins and pathways involving mitochondria-associated membranes ENSG00000042832 ENSG00000099194 ENSG00000100243 ENSG00000062282 PMC3794713__F2 mTOR and MAPK pathways PMC5922385__F8 Model of miR-652-mediated mechanism of EMT in PC3 cells PMC8829035__F9 Trilobatin, a Natural Food Additive, Exerts Anti-Type 2 Diabetes Effect Mediated by Nrf2/ARE and IRS-1/GLUT2 Signaling Pathways ENSG00000181019 ENSG00000087842 ENSG00000079999 PMC5859169__F4 Alzheimer’s disease pathway and enriched gene ontology with Down-regulated genes ENSG00000070831 ENSG00000050748 ENSG00000198793 ENSG00000130477 ENSG00000132388 ENSG00000078668 ENSG00000159593 ENSG00000065559 ENSG00000133318 ENSG00000143933 ENSG00000004779 ENSG00000105402 ENSG00000104888 ENSG00000132639 ENSG00000179520 ENSG00000067715 ENSG00000165264 ENSG00000178127 ENSG00000221823 ENSG00000267855 ENSG00000110975 ENSG00000136521 ENSG00000131174 ENSG00000213619 ENSG00000197959 ENSG00000147669 ENSG00000189043 PMC3871865__F1 Photoreceptor cell death and rescue in retinal detachment and degenerations ENSG00000132906 ENSG00000162711 ENSG00000150782 ENSG00000168040 ENSG00000064012 ENSG00000164305 PMC8274179__F1 Cell death as part of innate immunity: Cause or consequence? ENSG00000150782 ENSG00000005381 ENSG00000285379 PMC3760899__F3 Comparative Transcriptome Profiling of an SV40-Transformed Human Fibroblast (MRC5CVI) and Its Untransformed Counterpart (MRC-5) in Response to UVB Irradiation ENSG00000133895 ENSG00000109321 ENSG00000180543 ENSG00000116717 ENSG00000090971 ENSG00000258643 ENSG00000124762 PMC9615247__F1 STAT3 in the pathogenesis of nasopharyngeal carcinoma and its significance in anticancer therapy ENSG00000108702 ENSG00000162594 ENSG00000169245 ENSG00000019991 ENSG00000087245 ENSG00000145839 ENSG00000163235 ENSG00000138798 ENSG00000137265 ENSG00000168610 ENSG00000106546 PMC5316362__F2 Ingenuity®Pathway Analysis (IPA®) revealed significant overlap between the XDP signature and gene networks related to (A) RNA polymerase II (p = 1.19 × 10−6) and (B) NFKB (p = 1.36 × 10−12) ENSG00000253293 ENSG00000005073 ENSG00000169032 ENSG00000154188 PMC7817929__F3 Molecular Features of the Serrated Pathway to Colorectal Cancer: Current Knowledge and Future Directions ENSG00000157764 ENSG00000171444 ENSG00000170430 ENSG00000183579 ENSG00000108375 ENSG00000168646 PMC4150760__F3 Inferred non-small cell lung cancer pathway using the SpliceNet and RNASeqNet ENSG00000002330 ENSG00000157764 ENSG00000163235 ENSG00000138798 ENSG00000146648 PMC4246201__F10 Relationship between GPxs and the NFKB pathway in the antiproliferation action of butyrate ENSG00000211445 ENSG00000167468 ENSG00000162692 PMC6610297__F7 Metabolic pathway of glycerophospholipid, glycolysis, and TCA cycle under hypoxia stress ENSG00000163624 ENSG00000173599 ENSG00000198670 ENSG00000184207 ENSG00000026103 PMC4824143__F1 Smad and non-Smad transforming growth factorB1 (TGFB1) signaling pathways ENSG00000105329 PMC3464294__F4 Cell Stiffness Is a Biomarker of the Metastatic Potential of Ovarian Cancer Cells ENSG00000087095 ENSG00000156076 ENSG00000137673 ENSG00000162337 ENSG00000198793 ENSG00000112715 ENSG00000122194 ENSG00000141968 ENSG00000104368 ENSG00000182541 ENSG00000106683 ENSG00000169291 ENSG00000011422 ENSG00000149269 ENSG00000165879 PMC6458850__F6 The role of CXXC5 and molecular mechanism of KY19382 in longitudinal bone growth ENSG00000168036 ENSG00000171604 PMC2673912__F6 Activin Modulates the Transcriptional Response of LBT2 Cells to Gonadotropin-Releasing Hormone and Alters Cellular Proliferation ENSG00000149311 ENSG00000012048 ENSG00000134982 ENSG00000173039 ENSG00000123374 ENSG00000116717 ENSG00000075218 ENSG00000120438 ENSG00000112715 ENSG00000166851 ENSG00000140743 ENSG00000117399 PMC2673912__F8 Activin Modulates the Transcriptional Response of LBT2 Cells to Gonadotropin-Releasing Hormone and Alters Cellular Proliferation ENSG00000245848 ENSG00000168036 ENSG00000185591 PMC11396801__F1 Selection of Reference Genes in Siraitia siamensis and Expression Patterns of Genes Involved in Mogrosides Biosynthesis ENSG00000110921 ENSG00000167508 PMC8911477__F3 Dysregulation of mTOR Signaling after Brain Ischemia PMC6255979__F2 Non-canonical mechanisms whereby betaine inhibits IL-1B production ENSG00000162711 ENSG00000187796 ENSG00000125538 ENSG00000168040 PMC4248710__F13 KLF4-dependent miRs cooperatively promote RAS-ERK pathway activity by cotargeting of pathway inhibitors ENSG00000164056 ENSG00000166068 ENSG00000196712 PMC4037835__F1 The MDC–MMSET–UBC9–53BP1–BRCA1 pathway ENSG00000012048 ENSG00000033800 PMC8699127__F4 Tissue-Nonspecific Alkaline Phosphatase, a Possible Mediator of Cell Maturation: Towards a New Paradigm ENSG00000170365 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6615683__F6 Model describing the putative mechanism of synergetic interaction between PFK158 and erlotinib in WT and mutEGFR NSCLC cell lines ENSG00000146648 PMC5900789__F1 IL-10-mediated modulation of myeloid cells ENSG00000105397 ENSG00000170458 ENSG00000165030 ENSG00000115415 ENSG00000276051 ENSG00000172936 ENSG00000136869 ENSG00000110324 ENSG00000136235 ENSG00000168610 PMC6178360__F5 Metastatic adrenocortical carcinoma ENSG00000149311 ENSG00000005339 ENSG00000084676 ENSG00000148175 ENSG00000196498 ENSG00000168610 ENSG00000162104 ENSG00000178568 ENSG00000265203 PMC10930675__F8 RUNX2 and CXCR4 effects on melanoma cells ENSG00000198793 ENSG00000121966 PMC8579759__F4 Oh, the Mutations You’ll Acquire! A Systematic Overview of Cutaneous Squamous Cell Carcinoma PMC11656958__F7 Schematic diagram depicting that STING exerts antiviral innate immune response by activating pentose phosphate pathway ENSG00000183735 ENSG00000164430 PMC6071809__F6 Proposed signaling pathways implicated in the promoter-specific expression of CYP19 in Hs578t cells ENSG00000168610 PMC7779984__F2 Omega 3 Fatty Acids and COVID-19: A Comprehensive Review ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC7033213__F3 Top causal network explaining observed gene expression differences ENSG00000143799 ENSG00000100906 ENSG00000146648 ENSG00000064012 ENSG00000164305 PMC5989395__F2 Working model of the role of lysophosphatidic acid (LPA) at the maternal-conceptus interface in pigs ENSG00000136960 ENSG00000198670 ENSG00000171517 ENSG00000073756 PMC4521627__F3 Integrating physiological regulation with stem cell and tissue homeostasis ENSG00000168283 ENSG00000134086 ENSG00000142611 PMC6003554__F2 Association of genetic variants in ATR-CHEK1 and ATM-CHEK2 pathway genes with risk of colorectal cancer in a Chinese population ENSG00000149311 ENSG00000175054 ENSG00000183765 PMC5630004__F2 Drug targets on the TGFB signaling pathway PMC7750395__F9 Graphic abstract of IAV-induced acute lung injury ENSG00000189403 ENSG00000136869 ENSG00000005381 PMC5630004__F1 Context-dependent transforming growth factor B (TGFB) signaling outputs arise from pathway interactions ENSG00000163235 ENSG00000138798 PMC3114084__F2 Titin domain arrangement in the cardiac sarcomere and connectivity within a mechanical signaling network ENSG00000188554 ENSG00000022267 PMC8447269__F2 Hedgehog Pathway Inhibitors: A New Therapeutic Class for the Treatment of Acute Myeloid Leukemia ENSG00000128602 PMC11984845__F8 Proposed model integrating multi‐omics data of FIIN‐2 highlights the regulatory network of downstream and involved signaling pathways ENSG00000142627 ENSG00000198793 ENSG00000168610 ENSG00000146648 ENSG00000155099 PMC7947698__F1 The Wnt signaling pathway in transgenic mice ENSG00000134982 ENSG00000168036 PMC8447269__F1 Hedgehog Pathway Inhibitors: A New Therapeutic Class for the Treatment of Acute Myeloid Leukemia ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC7178546__F1 Signaling Model from CAR Antigen Binding Through ERK Activation, Incorporating Models from literatureArrows and bars indicate activating and inhibitory interactions, respectively ENSG00000177455 ENSG00000213658 ENSG00000104894 ENSG00000113263 PMC4426444__F2 Reconstructed metabolic pathways in the common ancestor of apicomplexans and dinoflagellates at the time of plastid gain (A) and in Hematodinium sp ENSG00000112977 ENSG00000182511 ENSG00000197429 ENSG00000026103 PMC11629464__F1 MiRNA regulation of apoptosis and autophagy in Mtb-infected macrophage ENSG00000111537 ENSG00000002330 ENSG00000170458 ENSG00000115415 ENSG00000150907 ENSG00000198793 ENSG00000112561 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC6691526__F2 Impact of ovarian cancer-exosomes on target cells during pre-metastatic niche formation ENSG00000026508 ENSG00000168036 ENSG00000100985 ENSG00000168610 PMC10381003__F2 The TLR signalling pathways with highlighted gene polymorphisms involved in OA susceptibility ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC2677410__F2 Novel signaling network as a critical rheostat for the biology and maintenance of the normal stem cell and the cancer-initiating cell ENSG00000198793 ENSG00000140464 PMC7717626__F1 Identity and the heterogeneity of extracellular vesicles and exosomes ENSG00000110651 ENSG00000010278 ENSG00000135404 PMC10533046__F3 Recent Advances in the Biosynthesis of Natural Sugar Substitutes in Yeast ENSG00000197429 PMC11012607__F4 Understanding the Impact of Polyunsaturated Fatty Acids on Age-Related Macular Degeneration: A Review ENSG00000119915 ENSG00000066322 ENSG00000197977 PMC3174190__F2 Autism-Associated Gene Expression in Peripheral Leucocytes Commonly Observed between Subjects with Autism and Healthy Women Having Autistic Children ENSG00000075856 ENSG00000162385 ENSG00000205810 ENSG00000065357 ENSG00000182774 ENSG00000274700 ENSG00000147381 ENSG00000124802 PMC10179295__F2 Paxillin participates in Wnt, integrin-FAK, and TGFB signaling pathways ENSG00000010810 PMC10179295__F3 Paxillin participates in MAPK and PI3K/AKT signaling pathways ENSG00000196090 ENSG00000291971 ENSG00000146648 PMC6513850__F8 Diagrammatic model summarising the proposed bimodal Wnt signalling regulation by DYRK1A, as reported in Figs – ENSG00000157540 ENSG00000134982 PMC8156652__F9 Insulin-Like Peptide Receptor-Mediated Signaling Pathways Orchestrate Regulation of Growth in the Pacific Oyster (Crassostrea gigas), as Revealed by Gene Expression Profiles PMC3430470__F5 The role of Monosaccharide Transport Proteins in carbohydrate assimilation, distribution, metabolism and homeostasis ENSG00000069482 ENSG00000166278 PMC7875919__F2 Lipid metabolism by the unfolded protein response ENSG00000131473 ENSG00000110721 ENSG00000118402 ENSG00000042832 ENSG00000115425 ENSG00000100288 ENSG00000113161 ENSG00000062282 ENSG00000157184 ENSG00000130164 ENSG00000138823 ENSG00000134324 ENSG00000198670 ENSG00000169174 ENSG00000026103 PMC9623391__F1 Temporal Profile of Kynurenine Pathway Metabolites in a Rodent Model of Autosomal Recessive Polycystic Kidney Disease ENSG00000116096 PMC6173648__F6 A hypothetical pathway that may underlie vibration-induced changes in gene transcription in the prostate ENSG00000185664 PMC6885365__F4 Proteomic Analysis of Primary Colon Cancer and Synchronous Solitary Liver Metastasis ENSG00000160789 ENSG00000122971 ENSG00000095380 PMC3396054__F3 TGFB activates Smad 2/3 and Smad1 pathway ENSG00000170365 PMC8710701__F8 Neutrophil Homeostasis and Emergency Granulopoiesis: The Example of Systemic Juvenile Idiopathic Arthritis ENSG00000245848 ENSG00000172216 ENSG00000115415 ENSG00000137193 ENSG00000123374 ENSG00000100985 ENSG00000168610 PMC4722119__F1 Regulation of fatty acid synthase by O-GlcNAcylation, Terra incognita ENSG00000047410 ENSG00000147162 ENSG00000026103 PMC4425321__F1 General scheme, illustrating BDNF-TrkB signaling through three main pathways in the neuronal cell (NC).Notes: PLCG pathway results in activation of neuronal plasticity and long-term memory formation via PKC, TRPC, and transcriptional factor CREB ENSG00000198793 PMC4425321__F2 Targeted delivery of brain-derived neurotrophic factor for the treatment of blindness and deafness ENSG00000070831 ENSG00000175104 PMC9339642__F1 Prognostic Roles of ceRNA Network-Based Signatures in Gastrointestinal Cancers ENSG00000185515 ENSG00000169554 ENSG00000134982 ENSG00000243910 ENSG00000198793 ENSG00000115339 ENSG00000169047 ENSG00000073849 ENSG00000131023 ENSG00000168610 ENSG00000150907 ENSG00000145321 ENSG00000096717 ENSG00000146648 ENSG00000109670 PMC8178780__F1 Mechanism underlying treatment of ischemic stroke using acupuncture: transmission and regulation ENSG00000136869 ENSG00000168610 ENSG00000117322 PMC4269194__F1 Spatiotemporal regulation of feeding response by O-GlcNAcylation ENSG00000147162 ENSG00000169047 PMC11866848__F6 Research progress of disulfidptosis in the TME ENSG00000128272 ENSG00000151012 ENSG00000079999 PMC11866848__F7 Relationship between disulfidptosis-related pathways and ICIs ENSG00000137265 ENSG00000115419 ENSG00000159399 PMC11866848__F4 SLC7A11 inhibiting ferroptosis in cancer cells ENSG00000108839 ENSG00000139514 ENSG00000167468 PMC7937699__F2 From Melanoma Development to RNA-Modified Dendritic Cell Vaccines: Highlighting the Lessons From the Past ENSG00000198793 PMC7010683__F8 Metformin reduces HGF-induced resistance to alectinib via the inhibition of Gab1 ENSG00000019991 ENSG00000198793 PMC6023766__F4 Apoptosis signaling pathway and its control by phosphorylation ENSG00000100290 ENSG00000002330 ENSG00000135116 ENSG00000104081 PMC11672879__F3 Protective mechanisms of phytochemicals in AMD ENSG00000181019 ENSG00000096717 ENSG00000023909 PMC5963348__F7 Schematic model for SIRT3-induced autophagy and its underlying mechanism in SH-SY5Y cells following rotenone treatment ENSG00000198793 ENSG00000047936 ENSG00000142082 PMC9354605__F3 Landscape of chimeric antigen receptor T cell therapy in breast cancer: Perspectives and outlook ENSG00000139193 PMC6023766__F2 Control of the PI3K and RAS signaling pathways by phosphatase signaling ENSG00000005882 PMC8748692__F9 Proposed model for ER-stress-induced AR decrease ENSG00000128272 PMC8291901__F2 Mitochondria in Mood Disorders: From Physiology to Pathophysiology and to Treatment ENSG00000096088 ENSG00000281879 ENSG00000096717 PMC6015598__F2 Dysfunctional cellular mechanisms in PD ENSG00000069329 ENSG00000112561 ENSG00000116675 PMC2922045__F1 TLR AGONISTS: Are They Good Adjuvants? ENSG00000174125 ENSG00000150455 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000134070 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC7320018__F6 Possible roles of TBC1D9 (A) and MFGE8 (B) ENSG00000122691 ENSG00000140545 ENSG00000168610 ENSG00000135506 PMC5461634__F3 Sub-network of cell cycle pathway regulated by C1orf132 and TMPO-AS1 ENSG00000112576 ENSG00000118007 ENSG00000250254 ENSG00000112118 ENSG00000205250 ENSG00000073111 ENSG00000076003 ENSG00000124762 ENSG00000183765 ENSG00000093009 ENSG00000103479 ENSG00000176248 ENSG00000136997 ENSG00000133740 ENSG00000105810 ENSG00000139687 ENSG00000282899 ENSG00000164109 ENSG00000116717 ENSG00000101224 ENSG00000117399 ENSG00000094804 ENSG00000114126 ENSG00000198176 ENSG00000132646 ENSG00000147082 ENSG00000263042 ENSG00000099860 ENSG00000129355 ENSG00000176386 ENSG00000135476 ENSG00000277273 ENSG00000164162 ENSG00000145386 ENSG00000118971 ENSG00000134480 ENSG00000153107 ENSG00000175054 ENSG00000129757 ENSG00000112242 ENSG00000115942 ENSG00000130222 ENSG00000135336 ENSG00000123374 ENSG00000112742 ENSG00000108055 ENSG00000175793 ENSG00000145604 ENSG00000077935 ENSG00000101972 ENSG00000002822 ENSG00000134057 ENSG00000135446 ENSG00000164754 ENSG00000149554 ENSG00000080839 ENSG00000175305 PMC11467144__F2 WNT signalling pathways in the intestinal crypt and potential therapeutic targets ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC2885591__F2 With TOR less is more: a key role for the conserved nutrient sensing TOR pathway in aging ENSG00000078053 ENSG00000198793 PMC10540641__F9 Schematic representing the manufacturing process of a targeted delivery system ENSG00000087245 ENSG00000026508 PMC6385430__F8 Suppression of WNT2 in signaling pathway ENSG00000162337 ENSG00000168036 PMC7341846__F5 Alterations to the kynurenine pathway in RCC ENSG00000105835 ENSG00000262635 ENSG00000162882 ENSG00000171097 ENSG00000183077 ENSG00000137944 ENSG00000188676 PMC7613831__F4 DMT induces a transcriptomic signature promoting FAO and opposing fibrosis in the renal cortex of ZDF and ZDSD rats ENSG00000157766 ENSG00000173599 ENSG00000161533 ENSG00000113790 ENSG00000132170 PMC9339518__F1 NAD+ redox balance, consumption and synthesis ENSG00000105835 ENSG00000162882 ENSG00000278488 ENSG00000183077 PMC5835334__F7 Schematic diagram shows that TM suppressed the secretion of NO, TNFA, and IL-1B by reducing the bioavailability of copper and the activity of its downstream ROS/TRAF6/AKT/NFKB signaling pathway ENSG00000125538 ENSG00000172936 ENSG00000175104 PMC2885591__F1 With TOR less is more: a key role for the conserved nutrient sensing TOR pathway in aging ENSG00000134086 ENSG00000169047 ENSG00000155792 ENSG00000167965 PMC11467144__F7 Summary Chart ENSG00000107779 ENSG00000137033 ENSG00000138798 ENSG00000198598 ENSG00000136859 ENSG00000136826 PMC11467144__F5 EGF signalling pathways in the intestinal crypt and potential therapeutic targets ENSG00000137033 ENSG00000113070 ENSG00000138798 PMC6751629__F8 The role of Asc1 in translation initiation ENSG00000168028 ENSG00000163435 ENSG00000107581 PMC9264948__F10 Prostate Apoptosis Response-4 (Par-4): A Novel Target in Pyronaridine-Induced Apoptosis in Glioblastoma (GBM) Cells ENSG00000168036 ENSG00000137831 ENSG00000171791 ENSG00000168040 ENSG00000026103 ENSG00000166128 PMC3986091__F3 Pathophysiology of Lung Injury Induced by Common Bile Duct Ligation in Mice ENSG00000134339 ENSG00000130208 ENSG00000143546 ENSG00000105697 ENSG00000186818 ENSG00000132965 ENSG00000118508 ENSG00000126218 ENSG00000163162 ENSG00000003137 ENSG00000166527 ENSG00000104140 ENSG00000166523 ENSG00000163734 ENSG00000146070 ENSG00000198125 ENSG00000112115 PMC6102093__F1 Schematic illustration showing mechanisms of smooth muscle cell (SMC) phenotypic switching ENSG00000116688 ENSG00000086991 ENSG00000100243 PMC7845653__F3 Podocyte Notch1 signaling in diabetic nephropathy (DN) ENSG00000148400 ENSG00000163914 ENSG00000077463 PMC7533414__F5 GSDMENT switches apoptosis to secondary necrosis/pyroptosis ENSG00000189403 ENSG00000164305 PMC7533414__F6 Gasdermins augment the mitochondrial apoptotic pathway ENSG00000278718 ENSG00000164305 PMC3115901__F4 The core biochemical network of the ceramide/sphingosine-1-phosphate rheostat ENSG00000139624 ENSG00000126266 ENSG00000172296 ENSG00000262243 PMC9322892__F2 Celiac Disease and Targeting the Molecular Mechanisms of Autoimmunity in COVID Pandemic ENSG00000162711 ENSG00000111537 ENSG00000137033 ENSG00000091592 ENSG00000132326 ENSG00000049768 ENSG00000132693 PMC3724896__F4 Differentiated Neuroprogenitor Cells Incubated with Human or Canine Adenovirus, or Lentiviral Vectors Have Distinct Transcriptome Profiles ENSG00000149311 ENSG00000144554 ENSG00000164109 ENSG00000089685 ENSG00000197299 ENSG00000051180 PMC12106535__F6 The apoptosis-related gene/tumor-associated antigen MUC1 in mesenchymal stem cell-mediated treatment of IBD ENSG00000178860 ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000136869 ENSG00000127948 PMC3951765__F1 NLRP3 inflammasome activation: CD36 serves double duty ENSG00000135218 ENSG00000187554 ENSG00000136869 PMC7506080__F1 Upregulation of AMH production in testicular Sertoli cells ENSG00000104899 ENSG00000125398 ENSG00000168066 ENSG00000285109 PMC9636637__F2 Iron metabolism in chronic diseases related to obesity ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000139515 PMC4069163__F6 Correction: De Novo Characterization of the Spleen Transcriptome of the Large Yellow Croaker (Pseudosciaena crocea) and Analysis of the Immune Relevant Genes and Pathways Involved in the Antiviral Response ENSG00000291603 ENSG00000110395 ENSG00000213658 ENSG00000117091 ENSG00000164066 ENSG00000010810 ENSG00000135446 ENSG00000163599 ENSG00000113263 PMC6950413__F1 Summarized natural and heterologous pathways for beta-carotene production investigated herein ENSG00000197429 PMC7854849__F1 Model indicating roles for MLH proteins in meiotic recombination ENSG00000057468 ENSG00000051180 ENSG00000178966 ENSG00000100206 ENSG00000126778 ENSG00000100625 PMC6287006__F5 KEGG analysis of hsa-miR-210 target genes ENSG00000137834 ENSG00000013016 ENSG00000163083 ENSG00000141068 ENSG00000112242 ENSG00000143761 ENSG00000108669 ENSG00000168461 ENSG00000197283 ENSG00000155980 ENSG00000183020 ENSG00000143590 ENSG00000184371 ENSG00000068383 ENSG00000135503 ENSG00000077782 PMC9250975__F2 Ubiquitin Binding Protein 2-Like (UBAP2L): is it so NICE After All? ENSG00000134057 ENSG00000170558 ENSG00000143569 ENSG00000168036 ENSG00000185591 PMC5457463__F3 Phosphoproteomic analysis of CCL2 treated DCs and confirmation of relevant signaling pathways ENSG00000108691 ENSG00000070831 ENSG00000140575 ENSG00000197943 ENSG00000067900 ENSG00000160360 ENSG00000099942 ENSG00000121807 ENSG00000087274 PMC9453003__F1 P38 MAPK Signalling in Testis Development and Male Fertility ENSG00000162552 ENSG00000169218 ENSG00000003137 ENSG00000125398 ENSG00000188425 ENSG00000102678 PMC7691587__F3 The mechanisms regulated by CMTMs in Hepatocellular Carcinoma ENSG00000140931 ENSG00000019991 ENSG00000087245 ENSG00000091317 ENSG00000002330 ENSG00000138798 ENSG00000170558 ENSG00000171791 ENSG00000168610 ENSG00000135446 ENSG00000136997 ENSG00000100985 ENSG00000153551 ENSG00000170293 ENSG00000146648 ENSG00000166091 ENSG00000140932 PMC6505517__F4 Interaction mapping of overlapping proteome changes in astrocytes treated with GBM a -stem and b -diff EVs ENSG00000280831 ENSG00000182774 ENSG00000186395 ENSG00000105329 ENSG00000167768 ENSG00000134910 ENSG00000241553 ENSG00000197746 ENSG00000165280 ENSG00000164327 ENSG00000168003 ENSG00000113558 ENSG00000136997 ENSG00000073792 ENSG00000105810 ENSG00000168028 ENSG00000023734 ENSG00000142192 ENSG00000143549 ENSG00000166130 ENSG00000116044 ENSG00000106244 ENSG00000132305 ENSG00000138029 ENSG00000198561 ENSG00000074695 ENSG00000133835 ENSG00000198931 ENSG00000126267 ENSG00000122786 ENSG00000140416 ENSG00000142541 ENSG00000135446 ENSG00000171759 ENSG00000072110 ENSG00000120438 ENSG00000047849 ENSG00000146648 ENSG00000176619 PMC7890213__F2 Nrf 2 pathway as a target in different neurodegenerative diseases ENSG00000197386 ENSG00000168685 PMC3233287__F2 Illustration of main mechanisms of trastuzumab resistance (in red) and targeted agents to circumvent resistance (in blue) ENSG00000121879 ENSG00000140443 PMC4936551__F1 Proposed scheme to describe how are interconnected with Ca2+-pH signaling components in polar growing cells ENSG00000018510 PMC5739026__F1 Three main classes of regulatory small RNAs ENSG00000100697 ENSG00000092847 ENSG00000113360 ENSG00000123908 PMC7890213__F1 Physiology of Nrf2 activation in both normal and stress conditions ENSG00000178573 ENSG00000079999 PMC7785591__F1 Cu/Zn Superoxide Dismutase (Sod1) regulates the canonical Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC9588473__F4 High DKK3 expression related to immunosuppression was associated with poor prognosis in glioblastoma: machine learning approach ENSG00000155011 ENSG00000050165 ENSG00000104332 PMC9588473__F5 High DKK3 expression related to immunosuppression was associated with poor prognosis in glioblastoma: machine learning approach ENSG00000107404 ENSG00000156076 ENSG00000155011 ENSG00000050165 ENSG00000168036 ENSG00000104332 ENSG00000154096 PMC9648670__F1 Interaction between gut microbiota and immune checkpoint inhibitor-related colitis ENSG00000205221 ENSG00000125538 ENSG00000132693 PMC3243091__F2 Molecular control of palatal shelf growth and patterning ENSG00000107779 ENSG00000070193 ENSG00000143867 ENSG00000090776 ENSG00000106511 ENSG00000163132 ENSG00000169184 ENSG00000164920 ENSG00000133216 ENSG00000131668 ENSG00000140285 ENSG00000164690 ENSG00000168779 PMC8698632__F3 Association of Circulating Heme Oxygenase-1, Lipid Profile and Coronary Disease Phenotype in Patients with Chronic Coronary Syndrome ENSG00000169174 PMC7589579__F2 Schematic representation of the endogenous and microbiota-associated pathways engaged in tryptophan breakdown in the gut environment ENSG00000106546 PMC7335670__F7 IQGAP1 control of centrosome function defines distinct variants of triple negative breast cancer ENSG00000140575 ENSG00000168036 PMC3442575__F4 Genes Involved in the Calvin Cycle and Photorespiration.(A) Schematic of the Calvin cycle and photorespiration pathway in C ENSG00000284320 ENSG00000291958 ENSG00000186051 ENSG00000062485 PMC11126959__F2 Biosynthesis of O-GlcNAc ENSG00000100522 ENSG00000198380 ENSG00000198408 ENSG00000124357 ENSG00000162066 ENSG00000013375 PMC11126959__F3 Autophagy pathway ENSG00000177169 ENSG00000198793 ENSG00000110931 ENSG00000099940 ENSG00000145782 ENSG00000057663 PMC11126959__F4 Impact of sustained changes in cardiac O-GlcNAcylation ENSG00000084093 ENSG00000147162 ENSG00000128272 ENSG00000198408 ENSG00000198793 ENSG00000185591 ENSG00000198626 ENSG00000100219 PMC12178005__F4 Signaling pathways of diverse types of collagen affecting tumor progression by regulating tumor immunity ENSG00000167613 ENSG00000125398 ENSG00000115415 ENSG00000291748 ENSG00000277335 PMC12178005__F5 Signal ways of diverse types of HA affecting tumor progression by regulating tumor immunity ENSG00000026508 ENSG00000168036 PMC7186400__F5 Paraburkholderia sp ENSG00000039537 PMC12178005__F3 ECM remodeling facilitates the formation of immunosuppressive TME ENSG00000162733 ENSG00000107562 ENSG00000113140 ENSG00000136869 ENSG00000126353 ENSG00000121966 PMC7313051__F2 Graphical summary of biological factors influencing anti-tumor immune response constituting three categories depending on anatomical level: tumor cell, tumor microenvironment, and the whole body ENSG00000111537 ENSG00000168036 ENSG00000273686 PMC9671658__F8 Glis1 and oxaloacetate in nucleus pulposus stromal cell somatic reprogramming and survival ENSG00000173599 ENSG00000171759 PMC6160959__F5 Orlistat from PxEA perspective ENSG00000175535 ENSG00000182333 ENSG00000143801 ENSG00000141480 ENSG00000148400 ENSG00000169710 ENSG00000137845 PMC9559691__F6 Metabolomic Analysis of the Takifugu Obscurus Gill under Acute Hypoxic Stress ENSG00000281324 ENSG00000162337 ENSG00000177058 ENSG00000198793 ENSG00000169047 ENSG00000155792 ENSG00000164327 ENSG00000145604 ENSG00000101407 ENSG00000168003 ENSG00000106070 ENSG00000145979 ENSG00000176641 PMC4398932__F5 Putative KF inhibition pathway in macrophage-mediated inflammatory signaling events ENSG00000291971 ENSG00000172936 ENSG00000136869 ENSG00000184216 PMC6698745__F2 Translesion synthesis ENSG00000010072 ENSG00000101751 ENSG00000132646 ENSG00000162607 ENSG00000070950 ENSG00000177084 ENSG00000122008 PMC5471801__F3 Enzymes involved in the metabolic pathway of PEB regimen PMC9559691__F5 Metabolomic Analysis of the Takifugu Obscurus Gill under Acute Hypoxic Stress ENSG00000145604 ENSG00000087095 ENSG00000171105 ENSG00000005882 ENSG00000123374 ENSG00000168610 PMC7522758__F1 Circadian Dysregulation of the TGFB/SMAD4 Pathway Modulates Metastatic Properties and Cell Fate Decisions in Pancreatic Cancer Cells ENSG00000154059 PMC10610897__F7 Interaction network of genes and co-expressed lncRNAs involved in IAV replication regulation in MDCK cells ENSG00000180353 ENSG00000213928 ENSG00000134321 ENSG00000105397 ENSG00000115415 PMC8026947__F3 Unfolded Protein Response Pathway ENSG00000065485 ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC5363412__F1 Top Network Associated with the DERs Selected by the Criteria of 4-fold Change in Whole BloodThe functions related to this network are defined as cancer, organismal injury and abnormalities, and reproductive system disease ENSG00000008710 ENSG00000112242 ENSG00000158055 ENSG00000152669 ENSG00000136997 ENSG00000171791 ENSG00000282899 PMC6473842__F2 Signaling pathways in mDA neuron development ENSG00000281324 ENSG00000117425 ENSG00000162337 ENSG00000183691 ENSG00000168036 ENSG00000125084 ENSG00000066468 ENSG00000107859 ENSG00000106571 ENSG00000162761 ENSG00000175832 ENSG00000050165 ENSG00000104290 ENSG00000183579 ENSG00000164690 ENSG00000077782 ENSG00000128602 PMC6491942__F10 Schematic depicting the sensitization mechanism of CsA to crizotinib ENSG00000239732 ENSG00000171435 ENSG00000168610 ENSG00000131196 ENSG00000010671 PMC8569340__F3 Chemoresistance in breast cancer: PI3K/Akt pathway inhibitors vs the current chemotherapy ENSG00000141867 ENSG00000111537 ENSG00000157764 ENSG00000138798 ENSG00000198793 ENSG00000125347 ENSG00000146648 PMC2662467__F6 Cell proliferation and apoptosis ENSG00000135446 ENSG00000134853 ENSG00000105810 ENSG00000146648 ENSG00000139687 ENSG00000196712 ENSG00000198625 PMC8569340__F1 Chemoresistance in breast cancer: PI3K/Akt pathway inhibitors vs the current chemotherapy ENSG00000163507 PMC8569340__F2 Chemoresistance in breast cancer: PI3K/Akt pathway inhibitors vs the current chemotherapy ENSG00000140992 ENSG00000168036 PMC9637915__F6 Proteomics unveil a central role for peroxisomes in butyrate assimilation of the heterotrophic Chlorophyte alga Polytomella sp. ENSG00000131473 ENSG00000089159 PMC11234216__F3 Signal mapping of transcription factors regulating the fate of HPCs ENSG00000125398 ENSG00000168036 PMC8532163__F9 Buddleoside-Rich Chrysanthemum indicum L. Extract has a Beneficial Effect on Metabolic Hypertensive Rats by Inhibiting the Enteric-Origin LPS/TLR4 Pathway ENSG00000170458 ENSG00000172936 ENSG00000136869 PMC5705877__F1 Biosynthesis of ceramide, sphingosine-1-phosphate, and ceramide-1-phosphate (a) ENSG00000100422 ENSG00000063176 ENSG00000102172 PMC9295051__F3 High Mobility Group A1 (HMGA1): Structure, Biological Function, and Therapeutic Potential ENSG00000171105 ENSG00000125398 ENSG00000168036 ENSG00000185591 ENSG00000141569 PMC9295051__F4 High Mobility Group A1 (HMGA1): Structure, Biological Function, and Therapeutic Potential ENSG00000148400 ENSG00000168610 PMC11525935__F7 MiR-126 can inhibit the PI3K signaling pathway, promote M1 macrophage polarization, and suppress the activation of FAK and Rac-1, thus accelerating the progression of UUO ENSG00000177575 ENSG00000169047 ENSG00000100985 PMC6446709__F1 Pathways for glycerolipid synthesis ENSG00000173599 ENSG00000198670 PMC5550862__F8 Role of SDC-4 in the regulation of the integrin and FGF signaling pathways ENSG00000123374 ENSG00000166278 PMC12203119__F2 Intestinal immunity and microbiota in gut health ENSG00000239732 ENSG00000136869 ENSG00000164342 PMC3949025__F11 Scheme depicting the inhibition of smooth muscle contraction via CB1 receptors ENSG00000163914 ENSG00000117152 PMC3601265__F2 Hypothetical pathways involved in MHC–self peptide-TCR recognition and PNH clone dominance ENSG00000164136 ENSG00000104432 PMC9654040__F2 Whole New Comprehension about ncRNA-Encoded Peptides/Proteins in Cancers ENSG00000291971 ENSG00000134982 ENSG00000145321 ENSG00000168036 ENSG00000146648 ENSG00000163507 PMC6324070__F3 The MAPK (ERK) signaling pathway in the KEGG pathway map (hsa04010) where the main path from growth factor to ERK kinase is marked in pink ENSG00000157404 ENSG00000049130 ENSG00000138798 ENSG00000146648 ENSG00000196712 ENSG00000185104 PMC10453554__F1 Cyclin K-CDK12/13 complexes affect important biological processes and contribute to cancer development by phosphorylating different targets ENSG00000167258 ENSG00000012048 PMC7425174__F2 PD-1-mediated immune regulation ENSG00000134982 PMC3656449__F6 The pathway triggered by Tat and leading to activation of ISGs by Tat in APCs infected by HIV ENSG00000089127 ENSG00000115415 ENSG00000137965 ENSG00000276561 PMC9424577__F6 An immunogenic cell injury module for the single-cell multiplexed activity metabolomics platform to identify promising anti-cancer natural products ENSG00000149311 ENSG00000144895 ENSG00000137275 ENSG00000134982 ENSG00000189403 ENSG00000136869 ENSG00000120868 ENSG00000168404 ENSG00000285379 PMC5347023__F6 High-Concentrate Diet Induced Milk Fat Decline via Glucagon-Mediated Activation of AMP-Activated Protein Kinase in Dairy Cows ENSG00000042832 ENSG00000026103 PMC5451860__F1 Role of WNT/beta-catenin pathway on aerobic glycolysis in gliomas ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC5451860__F2 Opposing effects of PPAR gamma and canonical WNT/beta-catenin signaling in gliomas ENSG00000136997 ENSG00000168036 PMC9513432__F3 How sphingolipids affect T cells in the resolution of inflammation ENSG00000172292 ENSG00000166278 ENSG00000143418 PMC9513432__F4 How sphingolipids affect T cells in the resolution of inflammation ENSG00000198793 ENSG00000049768 PMC9074815__F4 Neuronal Redevelopment and the Regeneration of Neuromodulatory Axons in the Adult Mammalian Central Nervous System ENSG00000163914 ENSG00000169783 ENSG00000075213 PMC6883319__F3 MetaCore-generated pathway of differentially expressed genes involved in protein kinase A (PKA) signaling ENSG00000140992 ENSG00000023516 ENSG00000282905 ENSG00000002330 ENSG00000100906 ENSG00000134982 ENSG00000172572 ENSG00000102893 ENSG00000105127 ENSG00000113448 PMC6883319__F4 MetaCore-generated pathway showing differentially expressed genes involved in sirtuin 6 regulation and function ENSG00000152266 ENSG00000135218 ENSG00000128272 ENSG00000112972 ENSG00000130164 ENSG00000101773 ENSG00000170522 ENSG00000169710 ENSG00000099194 ENSG00000106459 ENSG00000152556 PMC6070710__F8 Sepantronium Bromide (YM-155) on the Whole Transcriptome of MDA-MB-231 Cells: Highlight on Impaired ATR/ATM Fanconi Anemia DNA Damage Response ENSG00000065328 ENSG00000150991 ENSG00000135336 ENSG00000177084 ENSG00000112312 PMC11495891__F9 Application of EVs in the digestive system ENSG00000198125 ENSG00000026103 PMC9218731__F1 Cardiomyocyte death in sepsis: Mechanisms and regulation ENSG00000278718 ENSG00000162711 ENSG00000137275 ENSG00000167468 ENSG00000156026 ENSG00000136869 ENSG00000168404 ENSG00000110218 ENSG00000096717 ENSG00000285379 PMC11495891__F6 Application of EVs in circulatory system injury ENSG00000178860 ENSG00000198053 ENSG00000084774 PMC7654574__F8 Protein–protein interaction networks of energy metabolism canonical pathways affected by AgNPs/CDDP exposure in HepG2 and THLE2 cells ENSG00000262785 ENSG00000151726 ENSG00000140564 ENSG00000074800 ENSG00000100412 ENSG00000167468 ENSG00000087085 ENSG00000100348 ENSG00000120437 ENSG00000113790 ENSG00000091140 ENSG00000079557 PMC6883319__F6 MetaCore-generated pathway showing differentially expressed genes involved in mammalian target of rapamycin complex 1 (mTORC1) regulation ENSG00000140992 ENSG00000112964 ENSG00000138798 ENSG00000198793 ENSG00000155792 ENSG00000166484 ENSG00000135341 ENSG00000101407 ENSG00000129219 ENSG00000145979 ENSG00000136869 ENSG00000175104 ENSG00000159335 ENSG00000146648 ENSG00000062485 PMC7654574__F9 Protein–protein interaction networks of the sirtuin canonical pathway affected by AgNPs/CDDP exposure in HepG2 and THLE2 cells ENSG00000142192 ENSG00000265354 ENSG00000187531 ENSG00000105835 ENSG00000109320 ENSG00000179091 ENSG00000117118 ENSG00000198793 ENSG00000173039 ENSG00000142082 ENSG00000137845 ENSG00000283100 ENSG00000178127 ENSG00000213619 ENSG00000099800 ENSG00000099795 ENSG00000119013 ENSG00000096717 ENSG00000134809 PMC6883319__F7 MetaCore-generated pathway showing differentially expressed genes involved in ATP metabolism ENSG00000189283 ENSG00000154269 ENSG00000154027 ENSG00000136960 ENSG00000109743 ENSG00000004455 ENSG00000154678 ENSG00000068120 ENSG00000171408 ENSG00000113448 ENSG00000138801 PMC6883319__F8 MetaCore-generated pathway differentially expressed genes involved in antigen presentation by major histocompatibility complex (MHC) class I: cross-presentation ENSG00000172322 ENSG00000134594 ENSG00000152932 ENSG00000109113 ENSG00000197992 ENSG00000165280 ENSG00000173391 ENSG00000165527 ENSG00000118640 ENSG00000111737 ENSG00000168118 ENSG00000118508 ENSG00000019582 ENSG00000239732 ENSG00000265808 ENSG00000123892 ENSG00000103769 ENSG00000136869 ENSG00000172936 ENSG00000084733 ENSG00000038945 ENSG00000164342 ENSG00000090659 PMC6883319__F9 Pathway analysis by Ingenuity Pathway Analysis (IPA) ENSG00000100344 ENSG00000101350 ENSG00000138794 ENSG00000101470 ENSG00000116704 ENSG00000172572 ENSG00000065457 ENSG00000118707 ENSG00000142327 ENSG00000137563 ENSG00000126003 ENSG00000101473 ENSG00000101132 ENSG00000136997 ENSG00000164136 ENSG00000272398 ENSG00000101346 ENSG00000121060 ENSG00000026103 PMC5308639__F7 Interleukin-6 increases matrix metalloproteinase-14 (MMP-14) levels via down-regulation of p53 to drive cancer progression ENSG00000185591 ENSG00000168610 PMC9141422__F1 Ganglioside GM3 Synthase Deficiency in Mouse Models and Human Patients ENSG00000158470 ENSG00000115525 ENSG00000148154 ENSG00000174607 PMC3376735__F2 Regulation of the TGFB–BMP receptor complexes by reversible ubiquitylation ENSG00000135655 ENSG00000198742 ENSG00000123124 PMC4010202__F2 Proposed signaling mechanisms underlying the protective effects of mood stabilizing drugs against experimental stroke ENSG00000178860 ENSG00000185591 ENSG00000121966 PMC7895883__F1 Negative (blue) or positive (pink) regulation of TET2 in the inflammatory immune responses and related diseases ENSG00000101751 ENSG00000118520 ENSG00000049768 ENSG00000166169 ENSG00000171604 ENSG00000276561 PMC4999498__F2 Temporal regulation of Lsp1 O-GlcNAcylation and phosphorylation during apoptosis of activated B cells ENSG00000002330 ENSG00000070831 ENSG00000134982 ENSG00000198793 ENSG00000196591 ENSG00000081189 ENSG00000010671 ENSG00000121966 ENSG00000177455 ENSG00000095585 ENSG00000081026 ENSG00000019582 ENSG00000125249 ENSG00000067066 ENSG00000146094 ENSG00000077420 ENSG00000164362 ENSG00000026508 ENSG00000197943 ENSG00000169375 PMC6070710__F9 Sepantronium Bromide (YM-155) on the Whole Transcriptome of MDA-MB-231 Cells: Highlight on Impaired ATR/ATM Fanconi Anemia DNA Damage Response ENSG00000149311 ENSG00000175054 ENSG00000134057 ENSG00000139687 ENSG00000026103 PMC2737513__F1 IMP Dehydrogenase: Structure, Mechanism and Inhibition ENSG00000137198 PMC3058380__F5 Focal adhesions in osteoneogenesis ENSG00000172680 ENSG00000010810 PMC5354443__F11 Parvovirus B19 NS1 protein induces cell cycle arrest at G2-phase by activating the ATR-CDC25C-CDK1 pathway ENSG00000175054 PMC8377368__F1 Innate Immune System Orchestrates Metabolic Homeostasis and Dysfunction in Visceral Adipose Tissue During Obesity ENSG00000158473 ENSG00000137033 ENSG00000134982 ENSG00000107485 ENSG00000166090 ENSG00000049768 ENSG00000069667 ENSG00000026103 PMC4731262__F1 Wnt/Beta-catenin signaling in kidney injury and repair: a double-edged sword ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000100592 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC7762844__F1 mTOR signalling in the cell at a glance ENSG00000118515 ENSG00000155792 PMC3376735__F1 Logic of TGFB signalling from the membrane to nucleus ENSG00000157933 ENSG00000172216 ENSG00000162772 PMC5859335__F6 Relationship between cell cycle and common up-regulated genes identified between cancers ENSG00000118007 ENSG00000105329 ENSG00000134308 ENSG00000263042 ENSG00000129355 ENSG00000250254 ENSG00000112118 ENSG00000135476 ENSG00000205250 ENSG00000073111 ENSG00000277273 ENSG00000091651 ENSG00000164162 ENSG00000145386 ENSG00000076003 ENSG00000166851 ENSG00000124762 ENSG00000134480 ENSG00000093009 ENSG00000105325 ENSG00000116670 ENSG00000113558 ENSG00000136997 ENSG00000081377 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000112742 ENSG00000139687 ENSG00000253729 ENSG00000005339 ENSG00000108055 ENSG00000175793 ENSG00000101224 ENSG00000149311 ENSG00000145604 ENSG00000198176 ENSG00000156970 ENSG00000135446 ENSG00000132646 ENSG00000164754 ENSG00000149554 ENSG00000080839 PMC6337789__F2 Biological interaction networking of identified HCAECs phosphoproteins in KD ENSG00000047410 ENSG00000284832 ENSG00000104517 ENSG00000122786 ENSG00000073111 ENSG00000146457 ENSG00000124762 ENSG00000134899 ENSG00000105325 ENSG00000261371 ENSG00000112739 ENSG00000066044 ENSG00000132382 ENSG00000090060 ENSG00000204673 ENSG00000197879 ENSG00000116350 ENSG00000102119 ENSG00000188986 ENSG00000110713 ENSG00000140464 ENSG00000215301 PMC9270353__F2 Liquid–liquid phase separation in tumor biology ENSG00000149311 PMC8899988__F12 Novel HDAC11 inhibitor potentiates the tumoricidal effects of cordycepin against malignant peripheral nerve sheath tumor through the Hippo signaling pathway ENSG00000121621 ENSG00000185591 PMC1877048__F1 Nutritional Route Affects ERK Phosphorylation and Cytokine Production in Hepatic Mononuclear Cells ENSG00000170458 ENSG00000136869 PMC9497187__F9 Ceramide Kinase (CERK) Emerges as a Common Therapeutic Target for Triple Positive and Triple Negative Breast Cancer Cells ENSG00000167769 ENSG00000135587 ENSG00000143418 ENSG00000100422 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000170266 ENSG00000143753 ENSG00000292130 ENSG00000188611 ENSG00000078124 ENSG00000168350 PMC5800973__F4 KEY ROLE OF EXTRACELLULAR VESICLES IN THE METASTATIC PROCESS ENSG00000026508 ENSG00000110651 ENSG00000100985 ENSG00000121966 ENSG00000026103 PMC1783068__F1 Proximal B-cell receptor-mediated signalling pathways ENSG00000095585 ENSG00000100290 ENSG00000010810 ENSG00000010671 PMC8895352__F2 Androgen receptor (AR) signalling pathway associated PC IncRNAs (Adapted from Aird et al. ) ENSG00000168610 PMC8234323__F3 Asparagine: A Metabolite to Be Targeted in Cancers ENSG00000128272 ENSG00000143761 ENSG00000136997 ENSG00000103257 ENSG00000070669 PMC9497187__F1 Ceramide Kinase (CERK) Emerges as a Common Therapeutic Target for Triple Positive and Triple Negative Breast Cancer Cells ENSG00000135587 ENSG00000143418 ENSG00000139624 ENSG00000100422 ENSG00000063176 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000170266 ENSG00000143753 ENSG00000292130 ENSG00000119537 ENSG00000148154 ENSG00000168350 PMC6263005__F1 Neuroprotective modulation of the unfolded protein response in Marinesco-Sjögren syndrome: PERK signaling inhibition and beyond ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC10937592__F4 SCFAs bind with FFAR2, FFAR3 and GPR109A to improve hepatic steatosis, respectively ENSG00000026103 PMC10937592__F5 Possible mechanisms of SCFAs-induced epigenetic modifications to improve NAFLD ENSG00000100811 ENSG00000198793 ENSG00000134046 PMC2633716__F1 Genetic Variation in Calcium Sensing Receptor (CASR) and Risk of Colon Cancer ENSG00000019186 ENSG00000036828 PMC8348617__F2 Senescence-Associated Glycine max (Gm)NAC Genes: Integration of Natural and Stress-Induced Leaf Senescence ENSG00000118257 ENSG00000281857 PMC7726811__F1 PIDDosome pathway regulates HCC initiation and expansion ENSG00000177595 PMC10937592__F3 Mechanism of SCFAs madiate a decrease in cholesterol levels ENSG00000138075 ENSG00000167910 ENSG00000015520 PMC11210699__F2 Therapeutic effects of baicalin and baicalein ENSG00000177169 ENSG00000198793 ENSG00000168036 ENSG00000123374 ENSG00000136869 ENSG00000145386 PMC7064791__F1 CXCR3 receptor subtypes and related ligands that eventually result in CXCR3-B anti-tumor mechanisms, and responses in favor of tumor progression in the CXCR3-A signaling pathway following ligation of these ligands ENSG00000169245 ENSG00000291971 ENSG00000138755 PMC4206998__F2 MicroRNA induced by FSH at spermiogenesis ENSG00000112715 ENSG00000118971 ENSG00000140443 PMC11210699__F3 Therapeutic effects of baicalin and baicalein ENSG00000278718 ENSG00000162711 ENSG00000096717 PMC5811474__F6 Pictorial representation of p53 pathway regulated by E3 ligases and DUBs ENSG00000130939 ENSG00000177485 ENSG00000197579 ENSG00000036672 ENSG00000064393 ENSG00000204977 ENSG00000168411 ENSG00000149311 ENSG00000102226 ENSG00000162402 ENSG00000108375 ENSG00000167182 ENSG00000106346 ENSG00000121060 ENSG00000025293 ENSG00000026103 ENSG00000130726 ENSG00000072609 PMC8112354__F1 O-GlcNAcylation in Immune Cell Activation ENSG00000198408 ENSG00000175104 PMC5811474__F4 Illustration of E3 ligases and DUBs that regulate extrinsic pathway of Apoptosis ENSG00000078747 ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000130669 ENSG00000026103 PMC5811474__F5 Illustration of E3 ligases and DUBs that regulate TNF induced NFKB pathway ENSG00000102871 ENSG00000082512 ENSG00000111653 ENSG00000172046 ENSG00000083799 ENSG00000120913 ENSG00000168040 ENSG00000154124 ENSG00000175104 ENSG00000127191 ENSG00000143258 PMC4467418__F7 miR-1236 down-regulates alpha-fetoprotein, thus causing PTEN accumulation, which inhibits the PI3K/Akt pathway and malignant phenotype in hepatoma cells ENSG00000081051 PMC8953107__F5 Fucoidan (Undaria pinnatifida)/Polydopamine Composite-Modified Surface Promotes Osteogenic Potential of Periodontal Ligament Stem Cells ENSG00000002330 ENSG00000213658 ENSG00000171540 ENSG00000084774 PMC7084447__F3 An illustration demonstrating BER ENSG00000143799 ENSG00000292286 ENSG00000105486 ENSG00000132646 ENSG00000039650 ENSG00000140398 ENSG00000177084 ENSG00000042088 ENSG00000138385 PMC8953107__F6 Fucoidan (Undaria pinnatifida)/Polydopamine Composite-Modified Surface Promotes Osteogenic Potential of Periodontal Ligament Stem Cells ENSG00000124102 PMC5811474__F3 Regulation of Intrinsic pathway by E3 ligases and DUBs ENSG00000114125 ENSG00000002330 ENSG00000134982 ENSG00000104517 ENSG00000119401 ENSG00000109654 PMC2928709__F4 Observation of the differentially expressed genes on the human cell cycle (A) and transforming growth factor beta (TGFB) signaling pathways (B) modified from Kyoto Encyclopedia of Genes and Genomes (KEGG) (www.genome.jp/kegg/kegg1.html) ENSG00000121989 ENSG00000139567 ENSG00000156574 ENSG00000105656 ENSG00000277273 ENSG00000134480 ENSG00000137801 ENSG00000169231 ENSG00000183765 ENSG00000186340 ENSG00000113558 ENSG00000136997 ENSG00000123374 ENSG00000185591 ENSG00000139687 ENSG00000253729 ENSG00000104899 ENSG00000183434 ENSG00000170027 ENSG00000183691 ENSG00000134363 ENSG00000145604 ENSG00000100387 ENSG00000198176 ENSG00000113296 ENSG00000132646 ENSG00000164093 ENSG00000149554 ENSG00000080839 ENSG00000114739 PMC2902905__F1 Sub-Cellular and Signaling Mechanisms Underlying Polar PIN Localization.A model of regulators and pathways contributing to polar PIN localization in roots is proposed based on results discussed in this review ENSG00000127445 ENSG00000111237 ENSG00000028528 PMC9497674__F9 Gene Expression Profiles of Human Mesenchymal Stromal Cells Derived from Wharton’s Jelly and Amniotic Membrane before and after Osteo-Induction Using NanoString Platform ENSG00000138433 ENSG00000196591 ENSG00000175592 ENSG00000145386 ENSG00000178498 ENSG00000175029 ENSG00000090932 ENSG00000110042 ENSG00000106003 ENSG00000143801 ENSG00000168214 ENSG00000283780 ENSG00000074181 ENSG00000184384 ENSG00000128917 ENSG00000205155 ENSG00000196498 ENSG00000133961 ENSG00000114315 ENSG00000114166 PMC11545099__F1 B cell receptor signaling pathway ENSG00000177455 ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000198793 ENSG00000197943 ENSG00000010671 PMC5523853__F1 Key components of the stress response signaling network in C ENSG00000140992 ENSG00000157933 ENSG00000230989 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000118515 ENSG00000164327 ENSG00000096717 ENSG00000146648 ENSG00000140443 PMC10590753__F11 Differentially expressed proteins and metabolites KEGG annotation and visual analysis in the purine metabolism pathway ENSG00000142192 ENSG00000196839 ENSG00000254550 PMC8234323__F1 Asparagine: A Metabolite to Be Targeted in Cancers ENSG00000128272 ENSG00000144895 ENSG00000126804 ENSG00000070669 PMC8429149__F1 IL-36 cytokines in inflammatory and malignant diseases: not the new kid on the block anymore ENSG00000136696 ENSG00000136694 ENSG00000172936 ENSG00000175104 PMC8436187__F3 Release and activity of SQSTM1 in mouse sepsis ENSG00000278718 ENSG00000171105 ENSG00000284099 ENSG00000172936 ENSG00000136869 PMC9362849__F5 Genotoxicity-Stimulated and CYLD-Driven Malignant Transformation ENSG00000197530 ENSG00000137275 ENSG00000078747 ENSG00000102871 ENSG00000154059 ENSG00000083799 ENSG00000127191 PMC4100108__F4 The possible regulatory pathway of melanogesis activation ENSG00000101440 ENSG00000168036 PMC3828628__F1 IL-6 Paradox: Context Dependent Interplay of SOCS3 and AMPK ENSG00000169047 ENSG00000168610 PMC6722462__F5 Metabolite pathway analysis with Pearson correlation coefficient only edges corresponding to correlations whose similarity was less than 0.5 are shown ENSG00000102977 PMC4434617__F1 Role of transmethylation reactions in alcoholic liver disease ENSG00000205221 PMC9362849__F1 Genotoxicity-Stimulated and CYLD-Driven Malignant Transformation ENSG00000188486 ENSG00000149311 ENSG00000102871 ENSG00000083799 ENSG00000154124 PMC12185963__F10 TLR3 mediates central sensitization in a chronic migraine model induced by repeated nitroglycerin through the ERK signaling pathway ENSG00000157625 ENSG00000175104 ENSG00000164342 PMC8181875__F4 Novel therapies targeting hypoxia mechanism to treat pancreatic cancer ENSG00000173599 ENSG00000196782 ENSG00000189403 ENSG00000096717 ENSG00000128602 ENSG00000089163 ENSG00000146648 ENSG00000276043 PMC7680400__F4 Synaptic microRNAs in Alzheimer’s disease ENSG00000220205 ENSG00000096717 ENSG00000118257 ENSG00000196396 ENSG00000132639 ENSG00000133216 ENSG00000124785 ENSG00000067715 PMC7997823__F1 Signaling pathways of the main cytokines involved in cardiovascular diseases ENSG00000169291 ENSG00000102871 ENSG00000125538 ENSG00000127191 ENSG00000115594 PMC8181875__F1 Novel therapies targeting hypoxia mechanism to treat pancreatic cancer ENSG00000081041 ENSG00000168610 PMC8181875__F2 Novel therapies targeting hypoxia mechanism to treat pancreatic cancer ENSG00000173599 ENSG00000051180 ENSG00000168610 PMC8181875__F3 Novel therapies targeting hypoxia mechanism to treat pancreatic cancer ENSG00000154764 ENSG00000078399 ENSG00000170558 ENSG00000050165 ENSG00000168036 ENSG00000265972 PMC6748125__F6 Erythropoietin (Epo) binds to the Epo receptor (EpoR) to activate erythroid-specific gene transcription (EpoR, globins, glycophorin A (GPA), and miR-144/451) by GATA-1, resulting in hemoglobin (Hb) production ENSG00000177169 ENSG00000198793 ENSG00000187266 ENSG00000145782 ENSG00000057663 PMC8998143__F2 Melanin and Melanin-Functionalized Nanoparticles as Promising Tools in Cancer Research—A Review ENSG00000101440 PMC4677255__F2 Detected regulatory influences on the canonical Wnt pathway ENSG00000071575 ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134569 ENSG00000134982 ENSG00000292149 ENSG00000137310 ENSG00000168036 ENSG00000164176 ENSG00000141562 ENSG00000076604 ENSG00000140807 ENSG00000198742 ENSG00000155011 ENSG00000146122 ENSG00000154310 ENSG00000185269 ENSG00000168646 PMC5364150__F7 Shigella modulates the innate immune response in epithelial cells ENSG00000175104 ENSG00000127191 PMC3686324__F1 Osteoporosis – a current view of pharmacological prevention and treatment ENSG00000152266 ENSG00000281324 ENSG00000162337 PMC10861537__F7 Summary: impact of chemotherapy on CAF-S1 and CD8 T cell density in HGSOC ENSG00000180644 ENSG00000078098 PMC3686324__F3 Osteoporosis – a current view of pharmacological prevention and treatment ENSG00000281324 ENSG00000162337 PMC7570440__F1 Major longevity pathways and longevity-associated transcription factors in C ENSG00000198793 ENSG00000113558 ENSG00000112561 ENSG00000096717 PMC6905468__F8 Schematic summarizing the effect of ATR kinase inhibition in cisplatin-treated quiescent cells ENSG00000175054 ENSG00000164053 ENSG00000132646 PMC5772637__F6 Pathway studio analysis of genes analyzed in the study by the gene array analysis and qPCR ENSG00000182718 ENSG00000132906 ENSG00000168209 ENSG00000100906 ENSG00000109320 ENSG00000179091 ENSG00000269335 ENSG00000148926 ENSG00000173039 ENSG00000171791 ENSG00000170348 ENSG00000166920 ENSG00000164305 ENSG00000167772 ENSG00000114268 ENSG00000163017 ENSG00000100985 ENSG00000064012 PMC5772637__F7 Pathway studio analysis of proteins whose genes were analysed in the study by the gene array analysis and qPCR ENSG00000143799 ENSG00000132906 ENSG00000168209 ENSG00000100906 ENSG00000269335 ENSG00000148926 ENSG00000173039 ENSG00000171791 ENSG00000170348 ENSG00000166920 ENSG00000099203 ENSG00000164305 ENSG00000114268 ENSG00000163017 ENSG00000100985 ENSG00000064012 PMC5564816__F6 Ring finger protein 125, as a potential highly aggressive and unfavorable prognostic biomarker, promotes the invasion and metastasis of human gallbladder cancers via activating the TGFB1-SMAD3-ID1 signaling pathway ENSG00000170558 ENSG00000168036 ENSG00000125968 ENSG00000101695 PMC6044452__F8 Possible signaling mechanism for cigarette smoke and FGF23-mediated regulation of FGFR4/PLCG/calcineurin/NFAT pathway ENSG00000118972 ENSG00000160867 ENSG00000125538 PMC6877688__F3 KEGG pathway enrichment analysis of photosynthesis related genes in S6, S72, and R (control) groups ENSG00000173599 ENSG00000152430 ENSG00000100029 PMC7913870__F1 Hippo pathway ENSG00000101109 ENSG00000150457 ENSG00000131023 PMC7484659__F3 Schematic model illustrates the neuroprotective effects of THSG on STS-induced toxicity by restoring BNDF-TrkB/Akt signaling axis and inhibiting apoptosis PMC4074185__F3 Hereditary leiomyomatosis and renal cell carcinoma ENSG00000079999 PMC7913870__F3 Therapeutic targets to reactivate the Hippo pathway ENSG00000101109 ENSG00000263528 ENSG00000073910 ENSG00000105656 ENSG00000150457 ENSG00000131023 PMC6877688__F4 The endocytosis pathway ENSG00000131475 ENSG00000176108 ENSG00000130164 ENSG00000078053 ENSG00000165527 PMC7573881__F5 Network of lncRNAs involved in regulating the Th cell activation pathway in tongue squamous cell carcinoma ENSG00000186810 ENSG00000138378 ENSG00000111537 ENSG00000020633 ENSG00000107485 ENSG00000168610 PMC12120866__F6 Critical gene network analysis of the up-regulated DEGs in the M ENSG00000163739 ENSG00000122194 ENSG00000121966 ENSG00000128342 ENSG00000171560 ENSG00000081041 ENSG00000115163 ENSG00000178741 ENSG00000156467 ENSG00000277943 ENSG00000165264 ENSG00000183648 ENSG00000113905 ENSG00000226275 ENSG00000286522 ENSG00000136521 ENSG00000109390 ENSG00000122952 ENSG00000065518 ENSG00000117601 ENSG00000184270 ENSG00000145192 ENSG00000203852 ENSG00000145321 ENSG00000115009 PMC3398046__F5 MicroRNA Profiling in Mucosal Biopsies of Eosinophilic Esophagitis Patients Pre and Post Treatment with Steroids and Relationship with mRNA Targets ENSG00000003436 ENSG00000123091 ENSG00000101782 ENSG00000043462 ENSG00000196586 ENSG00000155307 ENSG00000143514 ENSG00000288512 ENSG00000107372 ENSG00000159346 ENSG00000157625 ENSG00000291555 ENSG00000170477 ENSG00000123610 PMC5290526__F7 A critical role for p38MAPK signalling pathway during reprogramming of human fibroblasts to iPSCs ENSG00000170558 PMC9293663__F7 Targeting macrophagic SHP2 for ameliorating osteoarthritis via TLR signaling ENSG00000169245 ENSG00000149968 ENSG00000125538 PMC3062664__F1 Metabolic insulin signaling pathway genes genotyped in the discovery cohort ENSG00000110395 ENSG00000010810 ENSG00000169047 ENSG00000165879 PMC2790217__F17 Akt regulates growth by phosphorylating and inhibiting the TSC1-TSC2 complex in drosophila ENSG00000198793 PMC5206652__F1 Identification of genetic susceptibility loci for intestinal Behçet’s disease ENSG00000177694 ENSG00000142192 ENSG00000117691 ENSG00000143942 ENSG00000124659 ENSG00000134243 ENSG00000276464 PMC5720977__F1 Wnt and Hippo signaling network that either promotes or inhibits Wnt signaling through cytoplasmic and nuclear interactions of the two pathways ENSG00000166167 ENSG00000134982 ENSG00000144560 ENSG00000168036 ENSG00000150457 ENSG00000131023 ENSG00000089225 PMC2349985__F1 Role of Leukotriene B4 Receptors in Rheumatoid Arthritis ENSG00000226275 ENSG00000125538 PMC3226036__F5 A schematic representation of the two classical apoptotic pathways in mammalian cells ENSG00000168040 ENSG00000026103 PMC8778800__F1 FGFR Pathway Inhibition in Gastric Cancer: The Golden Era of an Old Target? ENSG00000115008 ENSG00000198793 ENSG00000121879 PMC9605952__F1 Regulating pathways of ferroptosis ENSG00000148346 ENSG00000163930 ENSG00000161905 ENSG00000151012 ENSG00000291971 ENSG00000127528 ENSG00000168036 ENSG00000079999 ENSG00000168003 ENSG00000167468 ENSG00000188611 ENSG00000172977 ENSG00000155760 ENSG00000115107 ENSG00000071626 PMC9605952__F2 Ubiquitination on ferroptosis ENSG00000114770 ENSG00000151012 ENSG00000102226 ENSG00000026508 ENSG00000101752 ENSG00000079999 PMC9605952__F3 Autophagy on ferroptosis ENSG00000167468 ENSG00000057663 ENSG00000111481 PMC10254355__F4 CIN and MSI signaling pathways in colorectal epithelial cancer: A modified cartoon from KEGG depicts known activated pathways in colorectal epithelial cells ENSG00000124784 ENSG00000183735 ENSG00000002330 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000213341 ENSG00000146648 ENSG00000122008 PMC6894087__F7 Schematic drawing that illustrates the signaling pathway involving mTORC1/rpS6/Akt1/2 and Cdc42 utilized by NC1 peptide to induce Sertoli cell BTB remodeling in the testis ENSG00000070831 PMC4095764__F1 Physiological anticoagulant characteristics of blood vessels on endothelial cells ENSG00000003436 ENSG00000134982 ENSG00000173599 PMC9402792__F5 MRNA–miRNA–lncRNA Regulatory Network and Factors Associated with Prognosis Prediction of Hepatocellular Carcinoma ENSG00000152409 ENSG00000143878 ENSG00000141101 ENSG00000143507 ENSG00000136003 ENSG00000146648 PMC8431530__F3 Molecular Mechanisms of Alcohol-Induced Colorectal Carcinogenesis ENSG00000228716 ENSG00000116984 PMC2553572__F2 DSB repair pathways ENSG00000012061 ENSG00000149311 ENSG00000039650 ENSG00000051180 ENSG00000042088 ENSG00000139618 PMC6151343__F10 A schematic pathway for rosiglitazone induced HO‐1 expression in HPAEpiCs ENSG00000128050 ENSG00000136869 PMC12245916__F2 Signaling pathways for intestinal microbiota regulating the polarization and activation of intestinal macrophages ENSG00000172936 PMC7403206__F3 Podocyte insulin signaling ENSG00000171105 ENSG00000220205 ENSG00000102104 PMC6381368__F6 Schematic representation of the suggested pathway by which CAFs induce cell proliferation, EMT and metastasis in CRC cell ENSG00000198793 PMC8315016__F8 Cisplatin Induces Pyroptosis via Activation of MEG3/NLRP3/caspase-1/GSDMD Pathway in Triple-Negative Breast Cancer ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC9144739__F2 Vaccination against Bacterial Infections: Challenges, Progress, and New Approaches with a Focus on Intracellular Bacteria ENSG00000111537 ENSG00000186716 ENSG00000214285 PMC6350761__F1 Efforts in redesigning the antileukemic drug 6-thiopurine: decreasing toxic side effects while maintaining efficacy †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8md00463c ENSG00000137364 PMC6738830__F6 Proposed model for impaired apoptotic response to hMPV infection in NECs from asthmatics ENSG00000128272 ENSG00000144895 PMC7445530__F1 Regulatory mechanisms of BLACAT1 on proliferation, invasion, metastasis, tumor cell cycle control, apoptosis, autophagy, and chemoresistance in multiple human cancers ENSG00000087245 ENSG00000281406 ENSG00000170558 ENSG00000168036 ENSG00000100985 ENSG00000121807 ENSG00000178691 ENSG00000168610 PMC7457047__F1 Drugs and antibodies that affect the function of the neuromuscular junction ENSG00000206561 ENSG00000134569 ENSG00000030304 ENSG00000087085 PMC8526348__F2 Toxic effects of cell-free hemoglobin on the microvascular endothelium: implications for pulmonary and nonpulmonary organ dysfunction ENSG00000162711 ENSG00000150782 ENSG00000110799 ENSG00000291971 ENSG00000163914 ENSG00000000971 ENSG00000136869 ENSG00000162692 PMC8155534__F6 Ameliorative Effects of Osthole on Experimental Renal Fibrosis in vivo and in vitro by Inhibiting IL-11/ERK1/2 Signaling ENSG00000137070 PMC5013148__F9 Positive feedback regulation of type I IFN response mediated by IFNd-induced IRF3 and IRF7 activation in large yellow croaker ENSG00000115415 ENSG00000276561 PMC3953130__F2 Ack1 signaling pathway in normal and cancerous cells ENSG00000184012 ENSG00000159399 PMC11896877__F2 Activation process of nuclear factor kappa B (NFKB) and the regulation of the NFKB signaling pathway by the small ubiquitin-like modifier (SUMO) ENSG00000079387 ENSG00000163904 ENSG00000112701 PMC7555335__F3 Constitutive activation of STAT5 ENSG00000122025 ENSG00000163235 ENSG00000138798 ENSG00000198793 ENSG00000137193 ENSG00000187266 ENSG00000146648 PMC8634263__F9 Cyclic Mechanical Strain Regulates Osteoblastic Differentiation of Mesenchymal Stem Cells on TiO2 Nanotubes Through GCN5 and Wnt/Beta-Catenin ENSG00000134982 ENSG00000168036 ENSG00000168646 ENSG00000125084 PMC8164819__F5 Current understanding of epigenetics mechanism as a novel target in reducing cancer stem cells resistance ENSG00000023734 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000114315 ENSG00000178691 PMC8164819__F6 Current understanding of epigenetics mechanism as a novel target in reducing cancer stem cells resistance ENSG00000170365 ENSG00000156574 PMC7059188__F2 Soluble factor-activated signaling pathways in fibroblastic cells in CNT-exposed mouse lungs ENSG00000135404 PMC8202686__F3 A2B Adenosine Receptors and Sphingosine 1-Phosphate Signaling Cross-Talk in Oligodendrogliogenesis ENSG00000163914 PMC4643662__F3 The role of S100 proteins and their receptor RAGE in pancreatic cancer ENSG00000197956 ENSG00000196754 ENSG00000196154 ENSG00000164690 PMC7851123__F1 Genetic aberrations in DNA repair pathways: a cornerstone of precision oncology in prostate cancer ENSG00000012061 ENSG00000149311 ENSG00000175054 ENSG00000083093 ENSG00000144554 ENSG00000197299 ENSG00000051180 ENSG00000122512 PMC5872691__F1 One-carbon metabolism and DNA methylation ENSG00000228716 ENSG00000116984 PMC9332234__F1 Concomitant Nrf2 Targeting and Stem Cell Therapy in Cerebrovascular Disease ENSG00000100387 ENSG00000079999 PMC9634734__F1 BMP4 in adipose-derived stem cell differentiation: A minireview ENSG00000095739 ENSG00000204217 PMC2897904__F1 Proposed mechanisms of HDACi-induced apoptosis in colon cancer cells involving the mitochondrial pathway ENSG00000094631 ENSG00000061273 ENSG00000048052 ENSG00000100429 ENSG00000120868 ENSG00000108840 PMC7968000__F3 Tumor suppressive role of HNF4A ENSG00000171848 ENSG00000168036 ENSG00000124762 ENSG00000196628 PMC4819564__F2 Signaling cascades of Cripto-1, Notch/CSL, and Wnt/Beta-catenin ENSG00000140564 ENSG00000291971 ENSG00000134982 ENSG00000138798 ENSG00000241186 ENSG00000156574 ENSG00000102312 ENSG00000168036 ENSG00000133961 PMC6330122__F3 Neurotoxicity of Anesthetics: Mechanisms and Meaning from Mouse Intervention Studies ENSG00000171105 ENSG00000198793 ENSG00000146648 PMC7073187__F1 Main mechanisms by which the breakdown of tolerance to food antigens can occur ENSG00000137033 ENSG00000204671 ENSG00000113520 ENSG00000145777 ENSG00000166090 ENSG00000113525 PMC1797633__F1 Strategies of the different HCV proteins to antagonize IFN therapy ENSG00000144895 ENSG00000115415 ENSG00000027697 ENSG00000164342 PMC2724396__F1 Modified Lee-Heinrich model of wnt pathway ENSG00000134982 ENSG00000168036 PMC6106831__F5 Granulocyte activation and diapedesis mediators show greater induction during diestrus phase infection than in estrus ENSG00000166086 ENSG00000090863 ENSG00000150093 ENSG00000121966 ENSG00000135517 PMC5637726__F1 The role of the TGF-Beta-Smad and BMP-Smad signaling pathways in myocardial infarction and the mechanisms of some associated potential therapies ENSG00000275331 ENSG00000170365 ENSG00000137834 ENSG00000189403 ENSG00000138071 ENSG00000180875 ENSG00000283060 ENSG00000196689 PMC5729346__F1 The abnormalities in the pathway of tyrosine metabolism in tyrosinemia type I ENSG00000158104 ENSG00000171759 PMC8151573__F1 Oncogenesis, Microenvironment Modulation and Clinical Potentiality of FAP in Glioblastoma: Lessons Learned from Other Solid Tumors ENSG00000108691 ENSG00000105329 ENSG00000164690 ENSG00000078098 ENSG00000168610 PMC6477778__F1 Proposed sources of NOD1 activation and corresponding physiologic, endocrine, and cell tissue communication events leading to insulin resistance in different tissues ENSG00000173599 ENSG00000106100 PMC6168336__F6 In this illustration, potential mechanisms of tumor cell survival via crosstalk between components of the MET pathway, glycolysis, and autophagy are depicted ENSG00000167601 ENSG00000019991 ENSG00000198793 ENSG00000144848 PMC8307280__F2 Harnessing Carcinoma Cell Plasticity Mediated by TGFB Signaling PMC3835370__F1 Genomic Characterization of the Inherited Bone Marrow Failure Syndromes ENSG00000012048 ENSG00000136492 ENSG00000083093 ENSG00000077152 ENSG00000162607 ENSG00000139618 PMC7494613__F8 H3K27M mutations are dependent on a critical metabolic pathway also used by mIDH1 to regulate global H3K27me3 levels ENSG00000132510 ENSG00000159399 PMC9608452__F2 The microbiome and its metabolites in ankylosing spondylitis ENSG00000150782 ENSG00000134982 ENSG00000100219 PMC6971992__F2 ZIKV-induced ER stress initiates host cell unfolded protein response (UPR) ENSG00000134109 ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000162772 ENSG00000128965 PMC8097364__F2 Genome diversity and instability in human germ cells and preimplantation embryos ENSG00000012048 ENSG00000175054 ENSG00000187790 ENSG00000115392 ENSG00000187741 ENSG00000197299 ENSG00000112039 ENSG00000138385 ENSG00000139618 PMC3835370__F5 Genomic Characterization of the Inherited Bone Marrow Failure Syndromes ENSG00000182774 ENSG00000145912 ENSG00000124614 ENSG00000109534 ENSG00000182899 ENSG00000291996 ENSG00000213741 ENSG00000197728 ENSG00000138326 ENSG00000161970 ENSG00000171863 PMC9433691__SF1 Compressive force regulates GSK-3B in osteoclasts contributing to alveolar bone resorption during orthodontic tooth movement in vivo ENSG00000134982 ENSG00000168036 ENSG00000100985 PMC3920945__F3 Oncogenic and tumor suppressive autophagic pathways involved in miRNAs ENSG00000150907 ENSG00000184481 ENSG00000108840 PMC4580556__F5 The debulking signature ENSG00000145824 ENSG00000100234 ENSG00000087245 ENSG00000285109 ENSG00000100485 ENSG00000143387 ENSG00000170365 ENSG00000168283 ENSG00000105664 ENSG00000072694 ENSG00000133110 ENSG00000038427 ENSG00000116132 ENSG00000019549 ENSG00000291748 ENSG00000078098 ENSG00000123610 PMC3825743__F5 Quantitative Phosphoproteomic Profiling of Human Non-Small Cell Lung Cancer Tumors ENSG00000175054 ENSG00000111145 ENSG00000033327 ENSG00000002330 ENSG00000010810 ENSG00000198793 ENSG00000115904 ENSG00000170653 ENSG00000291761 ENSG00000145349 ENSG00000139687 ENSG00000133818 PMC9420296__F2 Connecting telomere maintenance and regulation to the developmental origin and differentiation states of neuroblastoma tumor cells ENSG00000166340 ENSG00000149311 ENSG00000175054 ENSG00000164362 ENSG00000166848 ENSG00000128513 PMC9518657__F1 Control of aging by the renin–angiotensin system: a review of C. elegans, Drosophila, and mammals ENSG00000130234 PMC8554658__F1 Molecular mechanisms of chemo‐ and radiotherapy resistance and the potential implications for cancer treatment ENSG00000168036 ENSG00000118971 ENSG00000168610 ENSG00000146648 PMC11671241__F7 Cortisol synthesis and secretion pathway and network of CRH‐ACTH‐cortisol signaling in Hu sheep ENSG00000130164 ENSG00000185231 ENSG00000170262 PMC11671241__F5 Thyroid hormone synthesis pathway and network of TRH‐TSH‐TH signaling in Hu sheep ENSG00000042832 ENSG00000165409 ENSG00000116830 ENSG00000163631 PMC11745090__F7 IL-6/JAK/STAT3 signaling pathway activation in mouse liver macrophages ENSG00000168610 ENSG00000146648 PMC11671241__F6 Thermogenesis in Hu sheep ENSG00000105664 ENSG00000105550 ENSG00000291720 PMC4270061__F2 Cofilin pathway in breast cancer invasion and metastasis ENSG00000138798 ENSG00000163914 ENSG00000146648 PMC6681775__F8 Regulatory mechanism of AQP1 in endometriosis ENSG00000162552 ENSG00000125084 PMC8797698__F1 Immunotherapy and radiation for high-grade glioma: a narrative review ENSG00000183735 ENSG00000049768 ENSG00000276561 ENSG00000106546 PMC6046295__F1 Mechanosignaling in normal keratinocytes and psoriasis ENSG00000198793 ENSG00000168036 ENSG00000036828 PMC4270061__F1 Cofilin pathway in breast cancer invasion and metastasis ENSG00000070831 ENSG00000291971 ENSG00000163914 ENSG00000146648 PMC7215894__F1 KLF11-mediated modulation of the TGFB signaling pathway in normal cells and tumors ENSG00000169375 PMC10377897__F3 KV Channel-Interacting Proteins in the Neurological and Cardiovascular Systems: An Updated Review ENSG00000148400 ENSG00000136826 PMC2862867__F4 Sites of action of curcumin on cancer cells ENSG00000171791 ENSG00000162692 ENSG00000118777 ENSG00000146648 PMC5452924__F1 Interaction of the E-cadherin-catenin complex ENSG00000291971 ENSG00000134982 PMC5452924__F2 Operating mode of the E-cadherin-catenin complex in tumor metastasis ENSG00000019991 ENSG00000134982 ENSG00000140575 ENSG00000138798 ENSG00000168036 ENSG00000146648 ENSG00000125084 PMC8436916__F9 DNMT3B decreases extracellular matrix degradation and alleviates intervertebral disc degeneration through TRPA1 methylation to inhibit the COX2/YAP axis ENSG00000104321 ENSG00000149968 ENSG00000088305 ENSG00000157766 ENSG00000100985 PMC7846853__F1 PI3K pathway in the context of BCR signaling along with various targets ENSG00000177455 ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000172936 ENSG00000168610 ENSG00000131196 ENSG00000010671 PMC9688888__F9 Guggulsterone Induces Apoptosis in Multiple Myeloma Cells by Targeting High Mobility Group Box 1 via Janus Activated Kinase/Signal Transducer and Activator of Transcription Pathway ENSG00000189403 ENSG00000168040 ENSG00000168610 PMC140098__F7 A novel inducible transactivation domain in the androgen receptor: implications for PRK in prostate cancer ENSG00000163914 PMC2581798__F3 Information flow through the JNK network ENSG00000135446 ENSG00000177606 ENSG00000197429 ENSG00000158828 ENSG00000123374 ENSG00000157106 PMC3035679__F3 Human inherited and mouse experimental defects in the cholesterol biosynthesis pathway that cause myelin disorders ENSG00000172893 ENSG00000135929 PMC3035679__F4 Human inherited and mouse experimental defects in the glycosphingolipids synthesis pathway that cause myelin disorders ENSG00000103089 ENSG00000148154 PMC3378544__F4 Tamarindus indica Extract Alters Release of Alpha Enolase, Apolipoprotein A-I, Transthyretin and Rab GDP Dissociation Inhibitor Beta from HepG2 Cells ENSG00000135218 ENSG00000110244 ENSG00000167910 ENSG00000113161 ENSG00000143921 PMC7827610__F1 Haem biosynthetic pathway and associated porphyria disorders ENSG00000110711 ENSG00000256269 PMC5683102__F3 Loss of NLRX1 exacerbates neural tissue damage and NFKB Signaling following brain injury ENSG00000023445 ENSG00000104856 ENSG00000102871 ENSG00000162924 ENSG00000168040 ENSG00000127191 ENSG00000125347 ENSG00000106100 ENSG00000108691 ENSG00000111537 ENSG00000115415 ENSG00000172936 ENSG00000175104 ENSG00000064012 ENSG00000184216 ENSG00000100065 PMC6947352__F11 Cell cycle pathway ENSG00000145604 ENSG00000108055 ENSG00000132646 ENSG00000135336 ENSG00000123374 ENSG00000277273 PMC8645889__F7 Hif-1A/Hsf1/Hsp70 signaling pathway regulates redox homeostasis and apoptosis in large yellow croaker (Larimichthys crocea) under environmental hypoxia ENSG00000284774 PMC5135597__F1 Intracellular cholesterol landscape: dynamic integrator of the immune response ENSG00000130164 ENSG00000138135 ENSG00000110048 ENSG00000142089 ENSG00000101558 PMC6034647__F1 From mice to men: TRPC3 in cerebellar ataxia ENSG00000101327 ENSG00000138741 PMC6025249__F7 Schematic diagram showing the mechanism of action of TFs against LPS-induced acute liver injury ENSG00000125538 ENSG00000169710 ENSG00000189403 ENSG00000023909 ENSG00000079999 PMC10898204__F5 KLF participates in the pyroptosis process of ulcerative enteritis through positive regulation of TXNIP/NLRP3 pathway ENSG00000278718 ENSG00000162711 ENSG00000265972 ENSG00000136826 PMC5437570__F3 Interaction of antagonists with Wnt5A/Ryk signalling in vascular endothelial cells ENSG00000168036 PMC5373476__F7 Lung Adenocarcinoma Distally Rewires Hepatic Circadian Homeostasis PMC6057448__F7 Death receptor signaling ENSG00000160789 ENSG00000102871 ENSG00000067900 ENSG00000168040 ENSG00000127191 ENSG00000111348 ENSG00000197694 ENSG00000148935 ENSG00000115317 ENSG00000160049 ENSG00000106683 ENSG00000183735 ENSG00000026103 PMC7834962__F1 IFN-related signaling pathways modulated by OncoTherad, zinc, vitamin D and glutamine during viral infections ENSG00000172936 PMC7754001__F7 Schematic diagram for the signalling pathways related to the EMT and airway remodelling in response to TGF‐B1 ENSG00000124795 PMC4527592__F7 Mechanism of Cisplatin-Induced Cytotoxicity Is Correlated to Impaired Metabolism Due to Mitochondrial ROS Generation ENSG00000074800 ENSG00000067057 ENSG00000231179 ENSG00000159399 PMC9166417__F1 PIKfyve as a drug target ENSG00000291802 ENSG00000112367 ENSG00000124102 ENSG00000115020 PMC6274779__F5 DEGs involved in glycerolipid metabolism and fatty acid degradation pathway ENSG00000157184 ENSG00000161533 PMC11788431__F8 C1GALT1-mediated regulation of Hh signaling and EWSR1::FLI1 expression ENSG00000182944 ENSG00000128602 PMC4991353__F2 Canonical and non-canonical Wnt pathways have differing effects in cancer ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000165527 PMC9647469__F3 Didang Tang inhibits intracerebral hemorrhage-induced neuronal injury via ASK1/MKK7/JNK signaling pathway, network pharmacology-based analyses combined with experimental validation ENSG00000132906 ENSG00000104365 ENSG00000291971 ENSG00000288174 ENSG00000168036 ENSG00000073756 ENSG00000164305 ENSG00000007171 ENSG00000132170 ENSG00000082175 ENSG00000134057 ENSG00000128052 ENSG00000177606 ENSG00000136997 ENSG00000125538 ENSG00000164400 ENSG00000100985 ENSG00000064012 ENSG00000167701 PMC3810304__F1 Potential pathways by which CKD modulates the accumulation of arterial macrophages ENSG00000108691 ENSG00000126353 ENSG00000162692 PMC8675148__F2 Exploiting natural antiviral immunity for the control of pandemics: Lessons from Covid-19 ENSG00000183735 ENSG00000108691 ENSG00000088888 ENSG00000105397 ENSG00000125538 ENSG00000108688 ENSG00000172936 ENSG00000121807 ENSG00000142166 PMC2808140__F2 Pathogenic Bacterial Proteins and their Anti-Inflammatory Effects in the Eukaryotic Host ENSG00000166484 ENSG00000175104 PMC6859545__F2 Cysteine residues are critical mediators of the antioxidant and heat shock responses ENSG00000284774 ENSG00000116044 ENSG00000079999 PMC5884251__F1 Oncogene and tumor suppressor gene products regulate glucose and glutamine metabolism in cancer ENSG00000125166 ENSG00000135423 ENSG00000074800 ENSG00000117650 ENSG00000158828 ENSG00000078237 ENSG00000077463 ENSG00000284194 ENSG00000159399 PMC9523668__F2 Targeting non-coding RNA H19: A potential therapeutic approach in pulmonary diseases ENSG00000162711 ENSG00000105329 ENSG00000167996 ENSG00000189403 ENSG00000136869 ENSG00000108821 ENSG00000102678 ENSG00000126778 ENSG00000168610 ENSG00000196712 PMC8945958__F1 Ferroptosis in Cardiovascular Diseases: Current Status, Challenges, and Future Perspectives ENSG00000228716 ENSG00000168003 ENSG00000151012 ENSG00000111684 ENSG00000185591 ENSG00000079999 PMC1410804__F7 Cdc42 regulates HF differentiation and cell–cell contacts in keratinocytes by modulating the turnover of Beta-catenin and plakoglobin ENSG00000070831 ENSG00000134982 ENSG00000168036 PMC3934763__F7 Insulin signaling KEGG pathway in adipose tissue ENSG00000171105 ENSG00000002330 ENSG00000110395 ENSG00000005882 ENSG00000198793 ENSG00000026103 PMC3934763__F8 PI3K-AKT signaling KEGG pathway in adipose tissue ENSG00000177455 ENSG00000124102 ENSG00000149089 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000169047 ENSG00000104894 PMC12206661__F7 PI3K-AKT and Hippo pathways play important roles in the regulation of ovarian tumor cell proliferation and PD-L1 expression ENSG00000213658 ENSG00000150457 ENSG00000131023 ENSG00000086730 PMC4333457__F6 Proposed human innate immune signaling pathways activated during V ENSG00000148346 ENSG00000162711 ENSG00000213928 ENSG00000143546 ENSG00000099985 ENSG00000163220 ENSG00000196954 ENSG00000168610 ENSG00000007171 ENSG00000285176 ENSG00000261150 ENSG00000102837 ENSG00000105397 ENSG00000115415 ENSG00000136869 ENSG00000172936 ENSG00000175104 ENSG00000113302 ENSG00000112115 ENSG00000005381 PMC9062100__F2 Toll-Like Receptors and Th Responses in Viral Myocarditis ENSG00000174123 ENSG00000174125 ENSG00000150782 ENSG00000187554 ENSG00000125538 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000168610 ENSG00000276561 ENSG00000164342 PMC8612763__F6 Metabolic changes associated with replicative lifespan (RLS) ENSG00000074800 PMC9062100__F4 Toll-Like Receptors and Th Responses in Viral Myocarditis ENSG00000136869 ENSG00000175104 ENSG00000164342 PMC3945033__F2 Computational simulation of eicosanoid profile in ATP-stimulated BMDM ENSG00000226275 ENSG00000161905 ENSG00000141086 ENSG00000095303 ENSG00000148344 ENSG00000164120 ENSG00000275565 ENSG00000073756 PMC8016325__F6 Moringa isothiocyanate-1 regulates Nrf2 and NFKB pathway in response to LPS-driven sepsis and inflammation ENSG00000178573 ENSG00000079999 PMC3679475__F1 Inflammatory adipokines suppress insulin signaling resulting in insulin resistance ENSG00000150907 ENSG00000198793 PMC5009362__F9 Keratin 8 limits TLR-triggered inflammatory responses through inhibiting TRAF6 polyubiquitination ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000184216 PMC5592202__F5 Schematic drawing of the efferent signaling pathway of the inflammatory reflex in the context of the cholinergic system in immune cells ENSG00000126233 ENSG00000158825 ENSG00000172936 ENSG00000167434 PMC11482718__F10 Graphic summary of potential signaling pathway involved in MG-induced lipotoxicity in vitro and in vivo ENSG00000042832 ENSG00000113161 ENSG00000169710 PMC10665998__F6 Long non‑coding RNA PEG13 regulates endothelial cell senescence through the microRNA‑195/IRS1 axis ENSG00000169047 ENSG00000162692 PMC8242058__F6 Endoplasmic reticulum stress, chondrocyte apoptosis and oxidative stress in cartilage of broilers affected by spontaneous femoral head necrosis ENSG00000132906 ENSG00000128272 ENSG00000197930 ENSG00000144895 ENSG00000100219 ENSG00000171791 ENSG00000064012 ENSG00000164305 ENSG00000057663 ENSG00000079999 PMC6441080__F7 The regulation of CP biosynthesis and the attachment to PG in S PMC8960436__F3 Celastrol Alleviates Autoimmune Hepatitis Through the PI3K/AKT Signaling Pathway Based on Network Pharmacology and Experiments ENSG00000171105 ENSG00000105329 ENSG00000291971 ENSG00000133063 ENSG00000112715 ENSG00000073756 ENSG00000164305 ENSG00000010671 ENSG00000132170 ENSG00000179295 ENSG00000180210 ENSG00000277571 ENSG00000117054 ENSG00000115415 ENSG00000149968 ENSG00000136997 ENSG00000015285 ENSG00000113263 ENSG00000100985 ENSG00000077782 ENSG00000146648 PMC8835572__F2 Cancer as a Metabolic Disorder ENSG00000136997 ENSG00000159399 PMC8829012__F3 HLA-G: Too Much or Too Little? Role in Cancer and Autoimmune Disease ENSG00000291603 ENSG00000276051 ENSG00000168610 PMC8835572__F4 Cancer as a Metabolic Disorder ENSG00000131473 ENSG00000135218 ENSG00000130164 ENSG00000198793 ENSG00000026103 PMC6261125__F6 Transcriptome-wide identification of genes involved in Ascorbate–Glutathione cycle (Halliwell–Asada pathway) and related pathway for elucidating its role in antioxidative potential in finger millet (Eleusine coracana (L.)) ENSG00000226275 ENSG00000281857 PMC10030587__F2 Key events in cancer: Dysregulation of SREBPs ENSG00000198793 ENSG00000161513 PMC5248531__F2 Mechanisms by which alteration of normal miRNA profiles can occur, leading to aberrant miRNA profiles in childhood solid tumours ENSG00000139546 ENSG00000136997 ENSG00000100697 ENSG00000124571 ENSG00000128191 ENSG00000113360 ENSG00000132341 PMC8003896__F3 Hcy metabolic pathways PMC8456981__F1 ROCK2 controls the balance between pro-inflammatory and Treg cell subsets, regulates cytoskeletal dynamics and profibrotic gene expression and drives both chronic inflammation and fibrosis in cGVHD ENSG00000137265 ENSG00000198670 ENSG00000049768 ENSG00000105639 ENSG00000168610 PMC2790850__F2 Aberrant Myc expression causes mammary cancer ENSG00000012048 ENSG00000136997 ENSG00000048028 PMC9309761__F4 Analysis of Competitive Endogenous RNA Regulatory Network of Exosomal Breast Cancer Based on exoRBase ENSG00000149311 ENSG00000175054 ENSG00000002330 ENSG00000085117 ENSG00000179091 ENSG00000136997 ENSG00000112378 PMC4120759__F1 ER stress and UPR ENSG00000128272 ENSG00000144895 ENSG00000070669 PMC8638098__F5 Gene regulatory networks analysis of muscle-invasive bladder cancer subtypes using differential graphical model ENSG00000108702 ENSG00000179934 ENSG00000090534 ENSG00000139269 ENSG00000274736 ENSG00000100385 ENSG00000123999 ENSG00000123496 ENSG00000127743 ENSG00000173578 ENSG00000292332 ENSG00000112964 ENSG00000119535 ENSG00000136696 ENSG00000184451 ENSG00000108342 ENSG00000163736 ENSG00000145777 ENSG00000166090 ENSG00000124391 ENSG00000169245 ENSG00000186810 ENSG00000226275 ENSG00000164404 ENSG00000115009 ENSG00000168685 ENSG00000110944 ENSG00000171855 ENSG00000102962 ENSG00000105329 ENSG00000156574 ENSG00000144476 ENSG00000174564 ENSG00000163702 ENSG00000161955 ENSG00000131142 ENSG00000177047 ENSG00000175189 ENSG00000292373 ENSG00000152785 ENSG00000173535 ENSG00000108688 ENSG00000116985 ENSG00000183682 ENSG00000292357 ENSG00000006606 ENSG00000143185 ENSG00000275718 ENSG00000099985 ENSG00000242689 ENSG00000054967 ENSG00000175505 ENSG00000277943 ENSG00000115607 ENSG00000096996 ENSG00000137077 ENSG00000184371 ENSG00000204217 PMC6829385__F1 MAPK signaling pathway: ERK1/2, JNK1/2, and p38 ENSG00000138798 PMC8638098__F6 Gene regulatory networks analysis of muscle-invasive bladder cancer subtypes using differential graphical model ENSG00000288269 ENSG00000148926 ENSG00000171049 ENSG00000175591 ENSG00000171388 ENSG00000151834 ENSG00000110148 ENSG00000152208 ENSG00000101958 ENSG00000120251 ENSG00000112964 ENSG00000146469 ENSG00000158748 ENSG00000157017 ENSG00000135577 ENSG00000157005 ENSG00000010310 ENSG00000124205 ENSG00000102468 ENSG00000274473 ENSG00000183395 ENSG00000162009 ENSG00000004948 ENSG00000115263 ENSG00000151617 ENSG00000113494 ENSG00000164251 ENSG00000135914 ENSG00000149295 ENSG00000133019 ENSG00000163394 ENSG00000135124 ENSG00000176358 ENSG00000120903 ENSG00000080644 ENSG00000117971 ENSG00000109991 ENSG00000180720 ENSG00000147432 ENSG00000188822 ENSG00000173080 ENSG00000174417 ENSG00000160013 ENSG00000147434 ENSG00000107014 ENSG00000102195 ENSG00000145040 ENSG00000288474 ENSG00000291946 ENSG00000124493 ENSG00000268089 ENSG00000248099 ENSG00000109738 ENSG00000147145 ENSG00000285456 ENSG00000274286 ENSG00000169836 ENSG00000187848 ENSG00000178473 ENSG00000132671 ENSG00000108556 ENSG00000175697 ENSG00000083454 ENSG00000078589 ENSG00000127533 ENSG00000169676 ENSG00000166863 ENSG00000183185 ENSG00000113327 ENSG00000145649 ENSG00000124089 ENSG00000166603 ENSG00000181195 PMC4595995__F3 HIV–tuberculosis-associated immune reconstitution inflammatory syndrome is characterized by Toll-like receptor and inflammasome signalling ENSG00000167207 ENSG00000056558 ENSG00000172936 ENSG00000185187 ENSG00000130159 PMC5953011__F1 Mechanisms regulating the canonical and non-canonical Wnt pathway ENSG00000157540 ENSG00000101849 ENSG00000134982 ENSG00000100888 ENSG00000292254 PMC6477904__F1 Blnc1 assembles ribonucleoprotein transcriptional complexes with hnRNPU to form a positive regulatory loop with EBF2 and Zbtb7b ENSG00000221818 ENSG00000160685 ENSG00000149187 PMC7465322__F7 Possible functional network of the AR induction pathway in sugarcane ENSG00000136997 PMC11734547__F6 Transcriptomics-based analysis of neurotoxic and reproductive effects in turbot (Scophthalmus maximus) after exposure to tris (2-chloroethyl) phosphate (TCEP) ENSG00000109163 ENSG00000070831 ENSG00000123104 ENSG00000146648 PMC2857169__F5 NFKB in conventional T-cell activation ENSG00000134982 ENSG00000113525 PMC3382229__F4 Peripheral Blood Transcriptome Identifies the Presence and Extent of Disease in Idiopathic Pulmonary Fibrosis ENSG00000275718 ENSG00000285318 ENSG00000102898 ENSG00000124107 ENSG00000133661 ENSG00000162298 PMC6790333__F5 Cell motility in cancer invasion and metastasis: insights from simple model organisms ENSG00000291971 PMC5640840__F8 Schematic diagram showing the observed changes induced by HCV in endoglin-associated cell signaling pathways ENSG00000170365 ENSG00000124766 ENSG00000171791 ENSG00000114315 ENSG00000125968 PMC9031373__F3 Evolving View of Uremic Toxicity ENSG00000146648 ENSG00000106546 PMC2575612__F4 Inter-individual mRNA expression variances in the mitogen-activated protein kinase (MAPK) signaling pathway in rheumatoid arthritis (RA) compared with normal control (NC) ENSG00000080823 ENSG00000127948 PMC3382229__F5 Peripheral Blood Transcriptome Identifies the Presence and Extent of Disease in Idiopathic Pulmonary Fibrosis ENSG00000285176 ENSG00000137673 ENSG00000285318 ENSG00000285251 ENSG00000285136 PMC6111853__F2 Proposed working model for the role of Rho GTPases in S1P‐induced GEnC activation in the presence of MPO‐ANCA‐positive IgG ENSG00000170989 ENSG00000180739 ENSG00000213694 ENSG00000125910 ENSG00000267534 PMC2873439__F7 CXCR5 activate PI3K isoforms through GAlpha-Src-FAK pathway or via GB/G pathway leading to subsequent activation of ERK1/2 ENSG00000124102 ENSG00000291971 PMC4557668__F8 JNK-dependent gene regulatory circuitry governs mesenchymal fate ENSG00000165556 ENSG00000140262 ENSG00000165030 ENSG00000136153 ENSG00000106511 ENSG00000090097 PMC5863732__F3 Mitochondrial Acylome Emerges: Proteomics, Regulation by Sirtuins, Metabolic and Disease Implications ENSG00000118520 ENSG00000036473 ENSG00000142082 PMC10586807__SF3_1. Correlation between CRISPR KO and CRISPRa screen gene hits within certain pathways ENSG00000129474 ENSG00000166167 ENSG00000154342 ENSG00000152348 ENSG00000137275 ENSG00000115415 ENSG00000198793 ENSG00000144848 PMC6161805__F5 Smoke-induced microRNAs and their target genes ENSG00000160789 ENSG00000137834 ENSG00000157764 ENSG00000115268 ENSG00000100697 ENSG00000131910 ENSG00000169032 ENSG00000127743 ENSG00000100219 ENSG00000111371 ENSG00000112115 ENSG00000114383 ENSG00000123908 PMC3665639__F2 Cell cycle regulation of Golgi membrane dynamics PMC5983164__F2 RAS effector pathways ENSG00000002330 ENSG00000169047 PMC4580101__F5 How the embryo makes a limb: determination, polarity and identity ENSG00000128713 ENSG00000253293 ENSG00000005073 ENSG00000128710 ENSG00000106571 ENSG00000164107 ENSG00000164690 ENSG00000128714 ENSG00000170178 PMC3712075__F6 Schematic diagram showing the involvement of CPT1C and ceramides in the hypothalamic ghrelin signaling pathway ENSG00000188909 PMC2254585__F5 In silico knockout of PLCG1 in the HGF stimulated signalling network ENSG00000291971 ENSG00000115904 ENSG00000168610 PMC3490020__F1 The main MicroRNA biosynthetic pathway ENSG00000092847 ENSG00000113360 ENSG00000123908 PMC8995768__F1 Bone Morphogenetic Proteins Shape Treg Cells ENSG00000107779 ENSG00000121989 ENSG00000137834 ENSG00000139567 ENSG00000135503 ENSG00000204217 ENSG00000125968 ENSG00000114739 PMC8422078__F1 Synthesis of GDP‐L‐fucose by the de novo and salvage pathway ENSG00000148803 ENSG00000254685 ENSG00000101346 ENSG00000112699 ENSG00000179163 PMC3857018__F1 Potential mechanism for active DNA methylation involving TET-mediated oxidation of 5mC, followed by TDG initiated BER pathway via recognition of 5hmC and 5fC (AP is an abasic site) (adapted from ()) ENSG00000187605 ENSG00000138336 ENSG00000139372 PMC9246655__F4 Insights from two independent transcriptomic studies of the bovine corpus luteum during pregnancy ENSG00000162496 ENSG00000198610 ENSG00000006757 ENSG00000109906 ENSG00000095015 ENSG00000197442 ENSG00000122779 ENSG00000140464 PMC8624719__F3 Innate Immune Antagonism of Mosquito-Borne Flaviviruses in Humans and Mosquitoes ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC9327212__F1 Small biomarkers with massive impacts: PI3K/AKT/mTOR signalling and microRNA crosstalk regulate nasopharyngeal carcinoma ENSG00000002330 PMC9239783__F6 Exploration of the Molecular Mechanism of Danzhi Xiaoyao Powder in Endometrial Cancer through Network Pharmacology PMC8624719__F1 Innate Immune Antagonism of Mosquito-Borne Flaviviruses in Humans and Mosquitoes ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000116688 ENSG00000172936 ENSG00000276561 ENSG00000171109 ENSG00000164342 PMC8624719__F2 Innate Immune Antagonism of Mosquito-Borne Flaviviruses in Humans and Mosquitoes ENSG00000172936 ENSG00000168040 PMC5487853__F2 Representation of cilia-associated molecules that have been implicated in DNA damage responses (DDR) ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000134057 ENSG00000182923 ENSG00000160602 ENSG00000123374 ENSG00000110274 ENSG00000148384 ENSG00000078674 PMC4747493__F8 Differential Roles for DUSP Family Members in Epithelial-to-Mesenchymal Transition and Cancer Stem Cell Regulation in Breast Cancer ENSG00000120875 ENSG00000138798 ENSG00000146648 PMC4565031__F2 Case study 1 (synthetic signaling pathway): Hypergraph showing every possible logic gate consistent with the prior knowledge network ENSG00000138798 ENSG00000095015 ENSG00000127191 ENSG00000135341 ENSG00000146648 PMC9043318__F2 miRNAs Can Affect Intestinal Epithelial Barrier in Inflammatory Bowel Disease ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC8192809__F2 Dual Role of Low-Density Lipoprotein Receptor-Related Protein 1 in Atherosclerosis PMC4978554__F1 CTLA-4 pathway inhibition ENSG00000134982 PMC3898176__F2 Toll pathway ENSG00000172936 ENSG00000168040 ENSG00000127191 PMC10963904__F4 Metabolic map of the L‐methionine synthesis pathway of E ENSG00000122966 ENSG00000172005 PMC6324668__F1 Novel clinical indenoisoquinoline topoisomerase I inhibitors: a twist around the camptothecins ENSG00000188486 ENSG00000175054 ENSG00000172716 ENSG00000042088 PMC10963904__F2 Metabolic map of the l‐methionine synthesis pathway of E ENSG00000122966 ENSG00000172005 PMC7292789__F1 Vertebrate complement cascades and the particular steps Lyme borreliae anti-complement protein interact ENSG00000113600 ENSG00000288512 ENSG00000244731 ENSG00000166278 ENSG00000182326 PMC8199487__F7 NBM-BMX, an HDAC8 Inhibitor, Overcomes Temozolomide Resistance in Glioblastoma Multiforme by Downregulating the Beta-Catenin/c-Myc/SOX2 Pathway and Upregulating p53-Mediated MGMT Inhibition ENSG00000147099 ENSG00000170430 ENSG00000168036 ENSG00000171791 ENSG00000102010 PMC10963904__F3 Metabolic map of the l‐methionine synthesis pathway of E ENSG00000122966 ENSG00000172005 PMC230332__F7 Extracellular and intracellular antagonism of BMP signaling by myostatin and TGFB ENSG00000170365 PMC3479242__F4 Optimizing the balance between host and environmental survival skills: lessons learned from Listeria monocytogenes ENSG00000117400 ENSG00000150787 PMC7786923__F8 Lnc-GAN1 repressed cell proliferation through cell cycle signaling pathway ENSG00000135446 PMC10742434__F1 Gut microbiota–host interplays in tryptophan and tyrosine metabolism, which affect mood and emotional states ENSG00000123454 PMC5524058__F8 Mechanisms of halofuginone action ENSG00000128272 ENSG00000144895 PMC3929326__F6 Regulation of Hippo-Yap1/Taz signaling by polarity complexes ENSG00000126016 ENSG00000186575 ENSG00000130545 ENSG00000150457 ENSG00000132849 ENSG00000131023 ENSG00000072415 PMC7182966__F3 Cancer hallmarks by the crosstalk between VEGF and Rho GTPase signaling pathways ENSG00000070831 ENSG00000291971 ENSG00000185808 PMC7926238__EV5 Models for disassembly of the metazoan replisome. The figure summarises data from this manuscript together with previous studies with early embryos of Caenorhabditis elegans and extracts of Xenopus laevis eggs ENSG00000183763 ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000093009 PMC5684302__F2 Interrelationships between growth factor, nutrient availability and energy sensing pathways in metabolic regulation in health ENSG00000198793 ENSG00000140443 PMC5056494__F1 Signal transduction pathway mediated through CLEC-2 ENSG00000213658 ENSG00000291971 ENSG00000010671 PMC5695117__F8 Proposed model for the autophagy process during E ENSG00000126775 ENSG00000120705 ENSG00000112561 PMC4864533__F1 Signaling pathways downstream of Group I mGluR stimulation PMC11928765__F2 Epithelial growth factor receptors (TGFBR/EGFR/KGFR) cellular signaling and their regulation by 16E5 ENSG00000019991 ENSG00000070193 ENSG00000163235 ENSG00000138798 ENSG00000104413 ENSG00000168610 ENSG00000146648 PMC5865411__F8 Proposed model for the novel dual functions of toll-like receptor (TLR)-10 in regulating IFN signaling ENSG00000174123 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC3369892__F8 Summary diagram of the proposed adrenomedullin (ADM) signaling pathway in the retina ENSG00000148926 ENSG00000131477 PMC3306173__F6 Synoviocyte innate immune responses: TANK-binding kinase-1 as a potential therapeutic target in rheumatoid arthritis ENSG00000183735 ENSG00000276561 ENSG00000164342 PMC3419830__F1 Mechanisms of action for therapeutic agents in treating or preventing HAE ENSG00000122194 PMC5740757__F4 Interaction pathway of miR-1270 and target genes ENSG00000140992 ENSG00000171105 ENSG00000033327 ENSG00000101109 ENSG00000182158 ENSG00000083290 ENSG00000105401 ENSG00000140968 ENSG00000115904 ENSG00000196782 ENSG00000141068 ENSG00000124126 ENSG00000138964 ENSG00000101849 ENSG00000078747 ENSG00000146592 ENSG00000183943 ENSG00000185591 ENSG00000161202 PMC6781492__F3 PPI networks and GO and KEGG pathway analyses for the top two positively co-expressed hub modules of SNHG7 in thyroid cancer ENSG00000110700 ENSG00000280831 ENSG00000131469 ENSG00000291931 ENSG00000198918 ENSG00000198755 ENSG00000105193 ENSG00000156482 ENSG00000136942 ENSG00000116251 ENSG00000108107 ENSG00000108826 ENSG00000236826 ENSG00000280858 ENSG00000196531 ENSG00000163882 ENSG00000063177 ENSG00000158042 ENSG00000100028 ENSG00000182004 ENSG00000105671 ENSG00000076924 ENSG00000141101 ENSG00000100142 ENSG00000165502 ENSG00000149273 ENSG00000077312 ENSG00000130520 ENSG00000122140 ENSG00000141759 ENSG00000285049 ENSG00000149806 ENSG00000144713 ENSG00000280548 ENSG00000277707 ENSG00000166441 ENSG00000108298 ENSG00000189306 ENSG00000125651 ENSG00000164587 ENSG00000162244 ENSG00000142534 ENSG00000198242 ENSG00000130811 ENSG00000161970 ENSG00000291938 ENSG00000145592 ENSG00000278270 ENSG00000132792 ENSG00000105568 ENSG00000104408 ENSG00000130255 ENSG00000174444 ENSG00000083845 ENSG00000053372 ENSG00000172809 ENSG00000161016 ENSG00000105771 ENSG00000101161 ENSG00000112651 ENSG00000100836 ENSG00000096080 ENSG00000005075 ENSG00000100353 ENSG00000175390 ENSG00000182774 ENSG00000213741 ENSG00000147604 ENSG00000138326 ENSG00000188846 ENSG00000171863 ENSG00000125691 ENSG00000008988 ENSG00000106245 ENSG00000134419 ENSG00000117614 ENSG00000071082 ENSG00000175467 ENSG00000197958 ENSG00000130332 ENSG00000205937 ENSG00000177600 ENSG00000168028 ENSG00000178035 ENSG00000177971 ENSG00000136718 ENSG00000162924 ENSG00000142541 ENSG00000109475 ENSG00000133112 ENSG00000084072 ENSG00000112306 PMC6781492__F4 Bioinformatics analyses for the top two negatively co-expressed hub modules of SNHG7 in thyroid cancer ENSG00000264364 ENSG00000033178 ENSG00000108395 ENSG00000118007 ENSG00000101367 ENSG00000291534 ENSG00000154001 ENSG00000159459 ENSG00000121879 ENSG00000153827 ENSG00000067369 ENSG00000123124 ENSG00000175054 ENSG00000004700 ENSG00000134086 ENSG00000078747 ENSG00000092148 ENSG00000253729 ENSG00000124102 ENSG00000153201 ENSG00000086758 ENSG00000078304 ENSG00000007168 ENSG00000113384 ENSG00000163539 ENSG00000069869 ENSG00000009335 ENSG00000198961 ENSG00000076321 ENSG00000004897 ENSG00000164597 ENSG00000157450 ENSG00000108587 ENSG00000173230 ENSG00000009413 PMC4656203__F1 Folate transport and folate mediated 1-carbon metabolism in eukaryotic cells (for gene abbreviations and enzyme commission numbers, see and , respectively) ENSG00000284320 ENSG00000065911 ENSG00000110203 ENSG00000136877 ENSG00000136371 ENSG00000103222 ENSG00000160282 ENSG00000035928 ENSG00000137563 ENSG00000145020 ENSG00000120254 PMC5548025__F7 A model of mTOR signaling pathways involved in AS ENSG00000198793 ENSG00000126353 ENSG00000096717 PMC5846794__F6 Combined use of protein biomarkers and network analysis unveils deregulated regulatory circuits in Duchenne muscular dystrophy ENSG00000104365 ENSG00000033327 ENSG00000170027 ENSG00000163629 ENSG00000109320 ENSG00000291971 ENSG00000077522 ENSG00000196504 ENSG00000184185 ENSG00000158517 ENSG00000137825 ENSG00000213341 ENSG00000173402 ENSG00000121879 ENSG00000160691 ENSG00000137807 ENSG00000130402 ENSG00000188130 ENSG00000145349 ENSG00000146648 ENSG00000198947 ENSG00000143632 PMC8063416__F2 Still’ disease interactome a considering all disease effectors and their direct interactors and b focusing on disease effectors and their interaction to drug targets, and comparison to c pathway enrichment results of sJIA gene expression data ENSG00000110944 ENSG00000169248 ENSG00000188379 ENSG00000134460 ENSG00000149294 ENSG00000189430 ENSG00000244731 ENSG00000092929 ENSG00000183918 ENSG00000096264 ENSG00000137496 ENSG00000057663 ENSG00000150782 ENSG00000173369 ENSG00000239732 ENSG00000149968 ENSG00000125538 ENSG00000284099 ENSG00000169429 ENSG00000113520 ENSG00000189403 ENSG00000026103 ENSG00000062485 ENSG00000143546 ENSG00000109320 ENSG00000163220 ENSG00000163221 ENSG00000173039 ENSG00000027697 ENSG00000166278 ENSG00000132170 ENSG00000169245 ENSG00000173372 ENSG00000184371 ENSG00000172936 ENSG00000113302 ENSG00000112115 ENSG00000135517 PMC4940627__F6 Schematic diagram of the mechanism of THs regulating gallstone formation in vivoFXR/RXR heterodimers which mediate phosphatidylcholine and bile salt transporters (ABC-B4 and ABC-B11) are down-regulated by THs ENSG00000005471 ENSG00000138075 ENSG00000130164 ENSG00000173599 ENSG00000073734 ENSG00000143921 PMC7288469__F4 CFTR Proteostasis Interactors ENSG00000092871 ENSG00000136986 ENSG00000101152 ENSG00000135823 ENSG00000001626 ENSG00000138942 ENSG00000169375 ENSG00000148719 ENSG00000162298 ENSG00000148396 PMC5192315__F2 Toll-like receptor signaling pathways ENSG00000173039 ENSG00000172936 ENSG00000136869 ENSG00000130159 ENSG00000150455 ENSG00000175104 ENSG00000167900 ENSG00000184216 PMC4183827__F9 Proposed DAT/PAT, sulfolipid, and phthiocerol dimycocerosate biosynthetic pathways ENSG00000166869 ENSG00000187446 ENSG00000117400 ENSG00000198598 PMC4351453__F8 A proposed model of our study is shown ENSG00000159167 ENSG00000198793 ENSG00000175567 PMC5327616__F9 BM-MSC modulates inflammation response through mTORC1-p70S6K/mTORC2-Akt Signal Pathway ENSG00000178860 ENSG00000125538 ENSG00000198793 ENSG00000164327 ENSG00000136869 ENSG00000167965 ENSG00000168610 ENSG00000164305 PMC4008360__F3 Ingenuity pathway network analysis of differentially expressed miRNAs ENSG00000118965 ENSG00000185015 ENSG00000263155 ENSG00000001561 ENSG00000149295 PMC2708980__F8 Proposed signaling pathway ENSG00000152689 ENSG00000171791 PMC12187936__F3 Anti- and pro-tumoral immunity regulated by tumor-resident bacteria ENSG00000111537 ENSG00000133048 ENSG00000118520 ENSG00000005381 PMC6690202__F1 Main pathways of NFKB activation ENSG00000104856 ENSG00000102871 ENSG00000157625 ENSG00000162924 PMC5240041__F3 Intracellular signaling pathways in lymphangiogenesis ENSG00000198793 ENSG00000150630 PMC5589692__F6 P38 pathway, a major pleiotropic cascade that transduces stress and metastatic signals in endothelial cells ENSG00000162889 ENSG00000106683 ENSG00000070831 ENSG00000010810 ENSG00000112715 PMC5589692__F7 P38 pathway, a major pleiotropic cascade that transduces stress and metastatic signals in endothelial cells ENSG00000291971 ENSG00000168036 PMC11878248__F2 Predicted targets of host miRNA responsive to HSV-1 infection PMC3836475__F4 Gene network associated with IFN pathway signaling ENSG00000213928 ENSG00000089127 ENSG00000119508 ENSG00000183486 ENSG00000157601 ENSG00000165280 ENSG00000160710 ENSG00000162772 ENSG00000155313 ENSG00000124762 ENSG00000135899 ENSG00000133106 ENSG00000187037 ENSG00000108679 ENSG00000134326 ENSG00000124226 ENSG00000177294 ENSG00000124201 ENSG00000117228 ENSG00000156738 ENSG00000115267 ENSG00000237693 ENSG00000125347 ENSG00000276561 ENSG00000172183 ENSG00000184979 ENSG00000154451 ENSG00000275214 ENSG00000115415 ENSG00000137965 ENSG00000059378 ENSG00000291555 ENSG00000111331 ENSG00000213512 ENSG00000143184 ENSG00000182179 PMC8073701__F5 Identification of Novel Biomarkers and Candidate Drug in Ovarian Cancer ENSG00000174125 ENSG00000284832 ENSG00000005339 ENSG00000001167 ENSG00000165030 ENSG00000196591 ENSG00000160741 ENSG00000125398 ENSG00000172216 ENSG00000108924 ENSG00000177606 ENSG00000173276 ENSG00000170653 ENSG00000285140 ENSG00000131323 ENSG00000043039 ENSG00000060566 ENSG00000124253 ENSG00000272333 ENSG00000146648 ENSG00000123268 ENSG00000095794 PMC4808796__F1 ATM, ATR and DNA-PK signalling pathways ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000163961 ENSG00000112130 PMC3595301__F1 Canonical or Wnt/Beta-catenin–TCF/LEF signaling ENSG00000138795 ENSG00000169071 ENSG00000070831 ENSG00000134982 ENSG00000168036 PMC3595301__F3 Crosstalk between Wnt and local inflammatory signaling pathways for the control of SVZ niche homeostasis ENSG00000168036 ENSG00000125084 PMC6643140__F7 Proposed mechanisms of TRIP13 functions in BCa ENSG00000146648 ENSG00000071539 ENSG00000125968 PMC7296543__F1 Canonical signaling pathway of TLRs ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC6909891__F1 Mechanistic target of rapamycin complex 1 (mTORC1) and mTORC2 signaling pathway and function ENSG00000177169 PMC102186__F9 Ras-mediated signaling pathways ENSG00000163914 PMC7498644__F2 Activation of the canonical NLRP3 inflammasome ENSG00000162711 ENSG00000150782 ENSG00000125538 ENSG00000172936 PMC3663908__F1 Major signaling pathways leading to cellular apoptosis ENSG00000002330 ENSG00000168040 ENSG00000115317 PMC2952128__F4 Functional gene networks identified using IPA from differentially expressed genes between control and 300 nM reversine-treated annulus fibrosus cells ENSG00000009709 ENSG00000168283 ENSG00000228278 ENSG00000159388 ENSG00000091409 ENSG00000196352 ENSG00000263057 ENSG00000136108 ENSG00000163728 ENSG00000139719 PMC8161229__F3 Chemokines in Prediabetes and Type 2 Diabetes: A Meta-Analysis ENSG00000187741 PMC5837202__F3 Effect of PCB126 exposure on the calcium signaling pathway ENSG00000182533 ENSG00000041982 ENSG00000156026 ENSG00000186716 PMC4458453__F1 Pathway of eukaryotic translation initiation ENSG00000163435 ENSG00000120690 PMC9266809__F6 miR-29c Increases Protein Synthesis in Skeletal Muscle Independently of AKT/mTOR ENSG00000100811 ENSG00000198793 PMC4489351__F1 EDA pathway and its downstream signaling ENSG00000186197 ENSG00000135960 ENSG00000175104 PMC9121316__F1 Forward single‐cell sequencing into clinical application: Understanding of ageing and rejuvenation from clinical observation to single‐cell solution ENSG00000198793 ENSG00000198846 PMC9374747__F4 In vivo transomic analyses of glucose-responsive metabolism in skeletal muscle reveal core differences between the healthy and obese states ENSG00000169047 ENSG00000184207 PMC6755815__F6 The pathway by which LPA increases LPP3 expression ENSG00000104856 ENSG00000173039 ENSG00000198670 PMC6682839__F3 Cell death and survival in the contrast of susceptible vs ENSG00000055211 ENSG00000038382 ENSG00000148411 ENSG00000163625 ENSG00000198176 ENSG00000117707 ENSG00000169902 ENSG00000164120 ENSG00000052802 ENSG00000106459 PMC6462535__F6 Ethanol regulation of stem cell differentiation via activation of RA signaling ENSG00000121207 ENSG00000138207 ENSG00000121039 ENSG00000128918 ENSG00000162496 ENSG00000143320 PMC10418437__F1 Signaling pathways activated by free mtDNA in the pathogenesis of metabolic syndrome ENSG00000162711 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000125538 ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000276561 PMC9374747__F6 In vivo transomic analyses of glucose-responsive metabolism in skeletal muscle reveal core differences between the healthy and obese states ENSG00000067066 ENSG00000290292 ENSG00000122180 ENSG00000288283 ENSG00000197757 ENSG00000175832 ENSG00000109906 ENSG00000173039 ENSG00000136826 ENSG00000124782 PMC3744328__F1 Sumoylation and regulation of cardiac gene expression ENSG00000142230 PMC3408825__F1 Autophagy pathway: signaling systems and three proposed membrane sources in autophagosome formation ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000189403 PMC6715590__F1 NLRP3 inflammasome activation pathway ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC12034127__F3 Iron overload activates the AKT/mTORC1 signalling pathway and inhibits TFEB expression, thereby inhibiting autophagy-mediated degradation of misfolded Alpha-syn and leading to neuronal death ENSG00000112561 PMC9454487__F1 Transforming Growth Factor-Beta Signaling in Cancer-Induced Cachexia: From Molecular Pathways to the Clinics ENSG00000086991 ENSG00000196218 PMC6174659__F1 P53 transcriptional pathway ENSG00000104499 ENSG00000149311 ENSG00000163235 ENSG00000138798 ENSG00000132646 ENSG00000171791 ENSG00000162772 ENSG00000047849 ENSG00000146648 PMC9454487__F2 Transforming Growth Factor-Beta Signaling in Cancer-Induced Cachexia: From Molecular Pathways to the Clinics PMC2724047__F6 Activation of the Akt (insulin signaling pathway) and FXR by bile acids in hepatocytes ENSG00000291971 ENSG00000146648 PMC8080632__F8 Schematic diagram illustrating the theory in the current study ENSG00000171532 PMC7080523__F4 Innate immune regulation of cGAS‐STING‐mediated immune pathways by the host or viral elements ENSG00000164430 ENSG00000105397 ENSG00000130656 ENSG00000163565 ENSG00000172936 ENSG00000276561 PMC2724047__F5 Major cell signaling pathways activated by bile acids in hepatocytes ENSG00000070831 ENSG00000065361 ENSG00000160867 PMC7861567__F5 Mild hyperandrogenemia in presence/absence of a high-fat, Western-style diet alters secretory phase endometrial transcriptome in nonhuman primates ENSG00000177606 ENSG00000136997 ENSG00000159588 ENSG00000205250 ENSG00000184481 ENSG00000196628 ENSG00000080839 PMC4836034__F1 Autophagy pathway and its interaction with HSV-1 ENSG00000177169 ENSG00000183735 ENSG00000198382 ENSG00000083290 ENSG00000144895 ENSG00000284099 PMC8086039__F1 Kill Two Birds with One Stone: Role of the RIPK-3 in Necroptosis and Inflammasome Activation ENSG00000162711 ENSG00000156026 ENSG00000168404 ENSG00000285379 PMC6112260__F9 Protein-protein interaction networks of DEGs involved in the staphylococcus aureus infection signaling pathway ENSG00000177694 ENSG00000115226 ENSG00000280831 ENSG00000105193 ENSG00000101266 ENSG00000136942 ENSG00000274619 ENSG00000280858 ENSG00000163162 ENSG00000071082 ENSG00000197958 ENSG00000104549 ENSG00000115268 ENSG00000164587 ENSG00000176014 ENSG00000205609 ENSG00000157349 ENSG00000127774 ENSG00000154124 ENSG00000278270 ENSG00000130255 ENSG00000161016 ENSG00000261456 ENSG00000224320 ENSG00000185129 PMC9389037__F1 The macrophage-to-myofibroblast transition in renal fibrosis ENSG00000291971 ENSG00000105639 PMC9693478__F3 Transgenic Mouse Models to Study the Development and Maintenance of the Adrenal Cortex ENSG00000162552 ENSG00000185231 ENSG00000183579 ENSG00000168036 ENSG00000134245 ENSG00000164690 ENSG00000170262 ENSG00000128602 ENSG00000168646 ENSG00000146374 PMC6828748__F4 Molecular pathway linked to oxidative stress response in E ENSG00000130706 ENSG00000175166 PMC1794588__F3 Small subnetwork identified for the shift from glucose to ethanol as carbon source ENSG00000186063 ENSG00000172005 ENSG00000171033 PMC3018162__F1 Schematic and mathematical representations of the main model assumptions ENSG00000291507 ENSG00000090402 PMC4026741__F1 Pattern recognition receptors in respiratory anti-viral immunity ENSG00000105397 ENSG00000291971 ENSG00000177606 ENSG00000175104 ENSG00000164342 PMC9585227__F1 Lipids for CD8+ TILs: Beneficial or harmful? ENSG00000089692 ENSG00000135218 ENSG00000111537 ENSG00000130164 ENSG00000168610 ENSG00000132170 PMC4197041__F1 Getting ready for building: signaling and autophagosome biogenesis ENSG00000177169 ENSG00000033327 ENSG00000144895 ENSG00000172936 ENSG00000136869 ENSG00000103257 ENSG00000175104 ENSG00000168610 ENSG00000146648 PMC6939855__F1 Mechanisms of endocrine therapy resistance in ER+ breast cancer and treatment strategy ENSG00000149311 ENSG00000124102 ENSG00000292286 ENSG00000135446 ENSG00000196712 ENSG00000064933 ENSG00000122512 PMC9081983__F3 Non-Coding RNA in Neurological Complications Associated With Enterovirus 71 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000090376 ENSG00000184216 PMC4641492__F1 A lncRNA to repair DNA ENSG00000149311 ENSG00000012048 ENSG00000105323 PMC8889147__F3 Network-based computational and experimental framework for repurposing compounds toward the treatment of non-alcoholic fatty liver disease ENSG00000163464 ENSG00000084093 ENSG00000140505 ENSG00000123454 ENSG00000087085 ENSG00000105953 ENSG00000043591 ENSG00000073756 ENSG00000084453 ENSG00000132170 ENSG00000163631 ENSG00000131238 ENSG00000104549 ENSG00000115419 PMC6728077__F1 DCs modulate Tfh-2 responses through the IL-6/STAT3 signaling pathway ENSG00000107485 ENSG00000168610 PMC3496878__F4 Phosphoinositide 3-kinase/Akt/mammalian target of rapamycin signaling pathway in cell proliferation in solid cancer ENSG00000198793 ENSG00000187840 PMC3496878__F1 Signal transduction in solid cancer cells including hepatocellular carcinoma ENSG00000172680 ENSG00000002330 ENSG00000070831 ENSG00000134982 ENSG00000179091 ENSG00000291971 ENSG00000198793 ENSG00000168610 ENSG00000163914 ENSG00000177606 ENSG00000078098 ENSG00000146648 ENSG00000196712 ENSG00000026103 PMC8115630__F6 Relative abundance of respective enzymes involved in central carbon metabolic pathways in “Ca. B. sinica” based on proteomeic analysis ENSG00000197713 ENSG00000073578 ENSG00000117118 ENSG00000173599 PMC8684084__F4 Profiles of immune cell infiltration and immune-related genes in the tumor microenvironment of osteosarcoma cancer ENSG00000104812 ENSG00000140992 ENSG00000002330 ENSG00000105401 ENSG00000169047 ENSG00000198793 ENSG00000134308 ENSG00000115904 ENSG00000214827 ENSG00000150093 ENSG00000167965 ENSG00000141564 ENSG00000171791 ENSG00000121879 ENSG00000012048 ENSG00000177455 ENSG00000103479 ENSG00000136997 ENSG00000123374 ENSG00000160447 ENSG00000168209 ENSG00000109320 ENSG00000213341 ENSG00000160741 ENSG00000117020 ENSG00000160867 ENSG00000040199 ENSG00000124253 PMC3780793__F1 Genes identified in the phosphatidylinositol and hedgehog signaling pathways ENSG00000162552 ENSG00000124102 ENSG00000161714 ENSG00000043355 ENSG00000133275 ENSG00000112210 ENSG00000136267 ENSG00000115850 ENSG00000143393 ENSG00000143398 ENSG00000150867 ENSG00000128602 ENSG00000101290 PMC6690396__F3 Histone methylation-dependent DDR mechanisms ENSG00000163961 ENSG00000181555 PMC3335850__F1 Gene Expression Analysis Implicates a Death Receptor Pathway in Schizophrenia Pathology ENSG00000161955 ENSG00000171791 ENSG00000168040 PMC10229232__F1 Krüppel-homologue 1 regulates the development of Tuta absoluta and its cascade regulation pattern in the juvenile hormone signalling pathway ENSG00000094804 ENSG00000092847 ENSG00000144713 PMC11856996__F3 Inhibitory Effect and Mechanism of Hexanal on the Maturation of Peach-Shaped Phallus impudicus ENSG00000124102 ENSG00000149489 ENSG00000166278 ENSG00000101752 PMC8495394__F3 P38G in Cancer: From review to outlook ENSG00000117525 ENSG00000168036 ENSG00000107485 ENSG00000178691 ENSG00000178568 PMC8495394__F1 P38G in Cancer: From review to outlook ENSG00000084093 PMC6546959__F4 Proposed ternatin biosynthetic pathway ENSG00000115263 ENSG00000145321 ENSG00000166278 PMC3348384__F1 miRNAs and estrogen action ENSG00000182944 ENSG00000128191 ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC9540541__F2 Metabolic engineering of oleaginous yeast Rhodotorula toruloides for overproduction of triacetic acid lactone ENSG00000065833 ENSG00000116748 ENSG00000157911 PMC8287254__F1 Lactate as Potential Mediators for Exercise-Induced Positive Effects on Neuroplasticity and Cerebrovascular Plasticity ENSG00000160097 ENSG00000112715 PMC11765629__F6 Metabolic pathway genes and metabolites altered in patients with MacTel ENSG00000228716 ENSG00000100596 ENSG00000092621 ENSG00000084734 ENSG00000146733 ENSG00000116984 PMC4727530__F2 BCL-2 family: key mediators of the apoptotic response to targeted anti-cancer therapeutics ENSG00000002330 ENSG00000157764 ENSG00000198793 ENSG00000146648 PMC2673958__F1 Role of Adenomatous Polyposis Coli (APC) and Microtubules in Directional Cell Migration and Neuronal Polarization ENSG00000070831 ENSG00000134982 ENSG00000163914 PMC7539770__F3 Influence of the SRSF1 splicing factor on malignancy through AKT signalling PMC8749970__F2 Tumor-Associated Macrophages in Hepatocellular Carcinoma Pathogenesis, Prognosis and Therapy ENSG00000169245 ENSG00000108691 ENSG00000275385 ENSG00000168036 ENSG00000115009 PMC11121235__F8 N-glycan metabolic pathway ENSG00000101901 ENSG00000253710 ENSG00000086848 ENSG00000136908 ENSG00000089597 PMC8625973__F1 Reciprocal Regulation of Hippo and WBP2 Signalling—Implications in Cancer Therapy ENSG00000126016 ENSG00000186575 ENSG00000078747 ENSG00000020633 ENSG00000150457 ENSG00000131023 PMC8625973__F2 Reciprocal Regulation of Hippo and WBP2 Signalling—Implications in Cancer Therapy ENSG00000186575 ENSG00000171735 ENSG00000150457 ENSG00000131023 PMC8625973__F5 Reciprocal Regulation of Hippo and WBP2 Signalling—Implications in Cancer Therapy ENSG00000132471 ENSG00000047644 ENSG00000150457 ENSG00000131023 PMC8625973__F6 Reciprocal Regulation of Hippo and WBP2 Signalling—Implications in Cancer Therapy ENSG00000132471 ENSG00000047644 ENSG00000150457 ENSG00000131023 PMC8625973__F7 Reciprocal Regulation of Hippo and WBP2 Signalling—Implications in Cancer Therapy ENSG00000132471 ENSG00000078747 ENSG00000108654 ENSG00000128191 ENSG00000113360 PMC11986138__F1 Expression changes of genes associated with protein processing in the endoplasmic reticulum by the correction of LRRK2 by BAC DNA ENSG00000291983 ENSG00000175054 ENSG00000128272 ENSG00000100387 ENSG00000173599 ENSG00000076641 ENSG00000198168 PMC2713831__F5 Local Network Topology in Human Protein Interaction Data Predicts Functional Association ENSG00000121989 ENSG00000023734 ENSG00000157933 ENSG00000064393 ENSG00000163083 ENSG00000136603 ENSG00000123999 ENSG00000164404 ENSG00000147255 ENSG00000175189 ENSG00000198742 ENSG00000177606 ENSG00000157450 ENSG00000140464 ENSG00000204217 ENSG00000114739 PMC10792990__F4 Mechanism of GB on independent risk factors for atherosclerosis ENSG00000042832 ENSG00000136869 ENSG00000168610 PMC5985050__F8 Proposed mechanisms by which PPARB/D regulates VLDLR levels and hepatic steatosis.PparB/D deficiency may result in an increase in VLDLR levels and hepatic steatosis through several mechanisms ENSG00000128272 ENSG00000042832 ENSG00000144895 ENSG00000105550 ENSG00000077782 PMC3560376__F2 The TLR9-Notch ligand (dll4) on Mycobacterium-dependent granuloma formation ENSG00000102962 ENSG00000239732 ENSG00000128917 ENSG00000172936 ENSG00000115009 ENSG00000112486 PMC4727530__F1 BCL-2 family: key mediators of the apoptotic response to targeted anti-cancer therapeutics ENSG00000100290 ENSG00000002330 ENSG00000135116 ENSG00000104081 PMC3060910__F1 Notch-2 Gene Is Regulated by Wnt Signaling in Cultured Colorectal Cancer Cells ENSG00000135547 ENSG00000283780 ENSG00000134982 ENSG00000173673 ENSG00000179111 ENSG00000168036 ENSG00000100060 ENSG00000273529 ENSG00000133961 ENSG00000106003 PMC2612083__F1 Cascading effects of stressors and inflammatory immune system activation: implications for major depressive disorder ENSG00000291631 PMC4042299__F3 The role of epigenetics in the biology of multiple myeloma ENSG00000156076 ENSG00000135446 ENSG00000168036 ENSG00000105810 ENSG00000168610 PMC8974835__F1 Pharmacological Rationale for Targeting IL-17 in Asthma ENSG00000039537 ENSG00000148400 ENSG00000175104 ENSG00000146648 PMC6963149__F2 Aberrant expression of long non-coding RNAs (lncRNAs) is involved in brain glioma development ENSG00000099330 ENSG00000169291 ENSG00000198793 ENSG00000146648 PMC5292133__F3 Network of the genes related with post-translational modification, cancer, and tumor morphology ENSG00000060982 ENSG00000277273 ENSG00000147274 ENSG00000276043 ENSG00000291983 ENSG00000111145 ENSG00000137364 ENSG00000102226 ENSG00000156110 ENSG00000005893 ENSG00000136997 ENSG00000172346 ENSG00000074410 ENSG00000285379 ENSG00000149503 PMC8625973__F8 Reciprocal Regulation of Hippo and WBP2 Signalling—Implications in Cancer Therapy ENSG00000132471 ENSG00000047644 ENSG00000150457 PMC5292133__F4 Network of the genes related with cancer and DNA replication, recombination, and repair ENSG00000291971 ENSG00000072274 ENSG00000125686 ENSG00000139289 ENSG00000142731 ENSG00000168938 ENSG00000165527 ENSG00000177084 ENSG00000080839 PMC9599649__F2 Cyclosporine A Delivery Platform for Veterinary Ophthalmology—A New Concept for Advanced Ophthalmology ENSG00000070831 ENSG00000160293 PMC7614835__S1 Purine Biosynthetic Pathway, the Pathway Transforms PRPP (Phosphoribosyl Pyrophosphate) into IMP (Inosine Monophosphate) in 10 Biosynthetic Stepsa PMC2928685__F1 Schematic diagram of the interaction of HH signalling on p53 and Nanog ENSG00000173599 ENSG00000128602 ENSG00000281857 PMC11854632__F1 Effects of miR-21 on key signaling pathways involved in SCI, with a focus on axonal regeneration, apoptosis, and inflammation ENSG00000002330 ENSG00000169071 ENSG00000242689 ENSG00000122756 ENSG00000198793 ENSG00000168036 ENSG00000131095 ENSG00000168040 ENSG00000168610 ENSG00000064012 ENSG00000164305 PMC3324922__F3 ALDH1A1 pathway ENSG00000004975 ENSG00000137834 ENSG00000107859 ENSG00000138795 ENSG00000165879 ENSG00000168036 ENSG00000188763 ENSG00000064692 ENSG00000165646 ENSG00000276996 ENSG00000158445 ENSG00000149295 PMC3324922__F4 NOS3 pathway ENSG00000149564 ENSG00000104365 ENSG00000120690 ENSG00000292234 ENSG00000077522 ENSG00000130402 ENSG00000127528 ENSG00000174640 ENSG00000079435 ENSG00000179348 ENSG00000137801 PMC6407676__F10 TGFB inducible epithelial-to-mesenchymal transition in renal cell carcinoma ENSG00000087245 PMC4108799__F3 HMGB1 binding to receptors and activating signal transduction pathway ENSG00000107562 ENSG00000226275 ENSG00000239732 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000121966 PMC6895093__F15 Apoptosis adapted from KEGG (ID: hsa04210), the know targets were signed in red; (B,C) the insulin signaling pathway adapted from KEGG (ID: hsa04910) the predicted targets and other human proteins were signed in red ENSG00000149311 ENSG00000002330 ENSG00000115155 ENSG00000026103 PMC4404103__F2 RNA Sequencing Reveals a Slow to Fast Muscle Fiber Type Transition after Olanzapine Infusion in Rats ENSG00000125166 ENSG00000130957 ENSG00000108515 ENSG00000073578 ENSG00000117118 ENSG00000163541 ENSG00000105953 ENSG00000172340 ENSG00000101365 ENSG00000143252 ENSG00000100412 ENSG00000164708 ENSG00000146701 ENSG00000091140 ENSG00000159399 ENSG00000141526 ENSG00000152556 ENSG00000062485 PMC2967585__F9 Mechanisms involved in alcohol-mediated suppression of type I IFN pathway in human hepatocytes ENSG00000120833 ENSG00000105397 ENSG00000115415 PMC8449753__F1 How FGF23 shapes multiple organs in chronic kidney disease ENSG00000118972 ENSG00000152266 ENSG00000293604 ENSG00000115339 PMC4001041__F1 Schematic illustrating NLR attenuation of canonical and non-canonical NFKB signaling ENSG00000104856 ENSG00000160703 ENSG00000142405 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC8027489__F1 PI3K/Akt/mTOR signaling and its main components ENSG00000002330 ENSG00000169047 ENSG00000123374 ENSG00000138092 PMC11942534__F3 5-Methylcytosine Methylation-Linked Hippo Pathway Molecular Interactions Regulate Lipid Metabolism ENSG00000114978 ENSG00000131023 PMC11942534__F4 5-Methylcytosine Methylation-Linked Hippo Pathway Molecular Interactions Regulate Lipid Metabolism ENSG00000114978 ENSG00000131023 ENSG00000026103 PMC8712723__F1 Evasion of I Interferon-Mediated Innate Immunity by Pseudorabies Virus ENSG00000183735 ENSG00000213928 ENSG00000239732 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000276561 ENSG00000140464 ENSG00000172183 ENSG00000142166 PMC4169022__F3 Characteristic DNA methylation profiles in peripheral blood monocytes are associated with inflammatory phenotypes of asthma ENSG00000182901 ENSG00000073584 ENSG00000011600 ENSG00000063322 ENSG00000122420 ENSG00000198053 ENSG00000110799 ENSG00000151835 ENSG00000122877 ENSG00000120885 ENSG00000171791 ENSG00000072571 ENSG00000126266 ENSG00000115138 ENSG00000168310 ENSG00000196498 ENSG00000090376 ENSG00000149564 ENSG00000115163 ENSG00000100448 ENSG00000163736 ENSG00000087460 ENSG00000117399 ENSG00000169836 ENSG00000067066 ENSG00000281614 ENSG00000168229 ENSG00000026508 ENSG00000124253 ENSG00000276838 ENSG00000156273 PMC5457776__F1 Insulin resistance in obesity ENSG00000169047 ENSG00000136869 PMC7216265__F3 lncRNAs affect glutaminolysis pathway in cancer ENSG00000065833 ENSG00000105953 ENSG00000253352 ENSG00000142082 ENSG00000082212 ENSG00000115419 PMC7216265__F4 Cancer glutaminolysis pathways through circRNAs ENSG00000168036 ENSG00000115419 PMC7216265__F1 Canonical glutaminolysis pathway ENSG00000131473 ENSG00000065833 ENSG00000135423 ENSG00000128272 ENSG00000165349 ENSG00000100412 ENSG00000169710 ENSG00000100033 ENSG00000146701 ENSG00000070669 ENSG00000115419 ENSG00000167701 PMC7216265__F2 miRNAs affect glutaminolysis in cancer ENSG00000100412 ENSG00000115419 PMC3474187__F9 Methionine sulfoxide and methionine sulfoxide reductase (MSR) redox cycle ENSG00000285250 ENSG00000116761 PMC9145045__F2 Type I and Type II Interferon Antagonism Strategies Used by Paramyxoviridae: Previous and New Discoveries, in Comparison ENSG00000183735 ENSG00000239732 ENSG00000088888 ENSG00000172936 ENSG00000107201 ENSG00000131323 ENSG00000121060 ENSG00000276561 ENSG00000164342 PMC9145045__F3 Type I and Type II Interferon Antagonism Strategies Used by Paramyxoviridae: Previous and New Discoveries, in Comparison ENSG00000159128 ENSG00000213928 ENSG00000187608 ENSG00000105397 ENSG00000167986 PMC6715589__F2 APP regulation of mitochondrial OXPHOS metabolism ENSG00000142192 ENSG00000171105 ENSG00000002330 PMC7409348__F5 Graphic representation of signaling pathways that promote gastric cancer PMC4949263__F2 Horizontal cell fate and cell type formation ENSG00000168267 ENSG00000016082 PMC6503447__F9 Prospective model for clarifying the role and regulation of ATG5 and ATG7 on autophagy and ER stress ENSG00000128272 ENSG00000144895 ENSG00000057663 PMC6199358__F1 (Left) In the “off” state, Beta-catenin binds with glycogen synthase kinase 3B (GSK3B), axin2, adenomatous colon polyposis protein (APC), and casein kinase-1 (CK- 1) ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000168646 PMC5559174__F14 Effects of graded levels of calorie restriction: XI. Evaluation of the main hypotheses underpinning the life extension effects of CR using the hepatic transcriptome ENSG00000198793 ENSG00000163914 ENSG00000096717 PMC6199358__F2 The Wnt/Beta-catenin and other signaling pathways ENSG00000138795 ENSG00000134982 ENSG00000168036 PMC8498718__F3 RNA-seq profile of African American men with a clinically localized prostate cancer ENSG00000109771 ENSG00000163945 ENSG00000178980 PMC7506056__F9 Aucubin attenuates liver ischemia-reperfusion injury by inhibiting the HMGB1/TLR-4/NFKB signaling pathway, oxidative stress, and apoptosis ENSG00000172936 ENSG00000125347 PMC4288522__F1 Intracellular signaling of mTORC1 and mTORC2 ENSG00000186575 ENSG00000169047 ENSG00000118515 ENSG00000155792 ENSG00000196712 PMC4116802__F2 Inflammation induces B cell activation ENSG00000186716 ENSG00000172936 ENSG00000168610 PMC3293571__F7 EMT downstream of TGFB and HMGA2 ENSG00000169554 PMC6628971__F1 Molecular mechanisms of the cGAS/STING pathway as a senescence-associated DNA damage sensor and inflammation trigger ENSG00000183735 ENSG00000197713 ENSG00000164430 PMC11975009__F2 VPS35 in Neurodegenerative Diseases ENSG00000281324 ENSG00000088836 ENSG00000069329 ENSG00000168036 PMC9019781__F1 WT1: The Hinge Between Anemia Correction and Cancer Development in Chronic Kidney Disease ENSG00000134086 PMC6748047__F2 Protein pathway analysis using serum proteins present in healthy controls and/or AA patients ENSG00000019991 ENSG00000172243 ENSG00000104969 ENSG00000144619 ENSG00000183762 ENSG00000171791 ENSG00000087303 ENSG00000163217 ENSG00000197461 ENSG00000186827 ENSG00000137801 ENSG00000148498 ENSG00000162733 ENSG00000108179 ENSG00000067606 ENSG00000188404 ENSG00000104371 ENSG00000102970 ENSG00000005381 ENSG00000135605 PMC8437933__F7 Ketamine ameliorates depressive-like behaviors in mice through increasing glucose uptake regulated by the ERK/GLUT3 signaling pathway ENSG00000134363 PMC6705454__F8 Modulation of IGF-1R expression levels is sufficient to restore the AKT/CREB and ERK/Elk-1 intracellular signaling pathway activation profile, resulting in SMN expression increase in SMA mice ENSG00000273772 ENSG00000140443 PMC7830527__F2 Proposed IFN-Gamma-dependent mechanisms of hyperprogression ENSG00000162711 ENSG00000136869 ENSG00000026103 PMC7830527__F3 Proposed CD38-dependent mechanisms of hyperprogression ENSG00000132478 ENSG00000091879 ENSG00000140443 PMC3233625__F3 Pleiotropic functions of EAPII/TTRAP/TDP2 PMC5963710__F7 Nonhuman primate kidney transcriptome in fetal development ENSG00000087095 ENSG00000166167 ENSG00000107404 ENSG00000156076 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000196470 ENSG00000132170 ENSG00000100592 ENSG00000100387 ENSG00000147869 ENSG00000113558 ENSG00000136997 PMC4239504__F2 Molecule-mediated signal pathways in the propagation of liver cancer during liver regeneration ENSG00000170365 ENSG00000198793 PMC9559313__F1 Targeting Glucose Metabolism Enzymes in Cancer Treatment: Current and Emerging Strategies ENSG00000110711 ENSG00000136872 ENSG00000159399 ENSG00000026103 PMC4191248__F2 Pancreatic cancer pathway diagram page ENSG00000163235 ENSG00000138798 ENSG00000146205 PMC3698421__F10 Schematic presentation of the Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3976613__F2 Non-selective autophagy regulation during diabetic nephropathy (DN) ENSG00000198382 ENSG00000164327 PMC9164466__F7 FANCC deficiency mediates microglial pyroptosis and secondary neuronal apoptosis in spinal cord contusion ENSG00000278718 ENSG00000125538 ENSG00000158169 PMC3712052__F1 Analysis strategy (–) to identify the putative regulatory effect of GWAS candidate () on FRMD3 regulation (), linking the gene to transcriptional regulation of the BMP pathway (–) and DN and suggesting a hypothetical regulatory model () ENSG00000135341 ENSG00000172159 PMC11392662__F8 Domperidone, a Dopamine Receptor D2 Antagonist, Induces Apoptosis by Inhibiting the ERK/STAT3-Mediated Pathway in Human Colon Cancer HCT116 Cells ENSG00000168610 ENSG00000149295 PMC7528617__F6 Analysis of HIF-1 signaling pathway ENSG00000134086 ENSG00000074800 ENSG00000168610 PMC4191248__F3 Hypoxia-inducible factor pathway ENSG00000134086 ENSG00000145020 ENSG00000166135 ENSG00000135506 PMC4191248__F6 Renal cell cancer pathway ENSG00000102977 PMC7311976__F1 Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000102312 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC7311976__F4 Ubiquitination in the Wnt signaling pathway ENSG00000118518 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000115392 ENSG00000168036 ENSG00000105559 ENSG00000196470 ENSG00000141562 ENSG00000086758 ENSG00000069869 ENSG00000078747 ENSG00000198742 ENSG00000183579 ENSG00000108375 PMC7311976__F5 Deubiquitination in the Wnt signaling pathway ENSG00000115464 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000083799 ENSG00000247746 ENSG00000155313 ENSG00000170242 ENSG00000136014 ENSG00000129204 ENSG00000101557 PMC8821659__F4 Comparative Study of Bacillus amyloliquefaciens X030 on the Intestinal Flora and Antibacterial Activity Against Aeromonas of Grass Carp ENSG00000122966 ENSG00000005882 ENSG00000036473 PMC3198061__F3 In individuals with high macrophage aggregation around dead adipocytes as CLS, activation stimuli such as IL-1, lipopolysaccharide (LPS) and lipopolysaccharide binding protein (LBP), and TNFA bind to their appropriate membrane receptors ENSG00000170458 ENSG00000169047 ENSG00000136869 ENSG00000100985 PMC9314411__F8 Proposed model of the UVB-triggered biochemical pathways in human dermal fibroblasts ENSG00000149311 ENSG00000138798 ENSG00000171791 PMC9031497__F4 Impact of Maternal Feed Restriction at Different Stages of Gestation on the Proteomic Profile of the Newborn Skeletal Muscle ENSG00000105953 ENSG00000131828 ENSG00000091140 ENSG00000152556 ENSG00000127884 PMC449769__F7 A model connecting telomere damage signalling and senescence-associated replicative arrest ENSG00000188486 ENSG00000149311 ENSG00000175054 PMC11832533__F9 Brief Introduction to the Functions of lncRNAs (Wilusz et al ENSG00000084733 ENSG00000253352 ENSG00000166851 PMC5411440__F1 Cellular and molecular pathogenesis of Helicobacter pylori infection in gastric carcinogenesis ENSG00000079112 ENSG00000068028 ENSG00000134982 ENSG00000026508 ENSG00000168036 ENSG00000172936 ENSG00000136869 ENSG00000169605 ENSG00000171791 ENSG00000168610 PMC7649776__F4 Psychiatric and cognitive SNPs mark eQTLs that are associated with gene expression within the neurotrophin signaling pathway ENSG00000142192 ENSG00000169291 ENSG00000002330 ENSG00000070831 ENSG00000169047 ENSG00000175104 PMC3188357__F2 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), is the major genotoxic heterocyclic amine generated from cooking meats at high temperatures ENSG00000140505 ENSG00000146247 ENSG00000140465 PMC8173334__F1 Diabetes and Cardiovascular Complications: The Epidemics Continue ENSG00000213928 ENSG00000137265 ENSG00000159335 ENSG00000276561 PMC9174413__F7 Comparative proteomic analysis on chloroplast proteins provides new insights into the effects of low temperature in sugar beet ENSG00000173599 ENSG00000105227 PMC3875938__F1 The mechanisms of Wnt/Beta-catenin pathway repression by 1,25(OH)2D3 in human colon carcinoma cells ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000196628 PMC8083961__F3 Regulatory Role of Oxygen Metabolism in Exercise-Induced Cardiomyocyte Regeneration ENSG00000198793 ENSG00000096717 ENSG00000178568 ENSG00000140443 PMC8268912__F1 Brain Symptoms of Tuberous Sclerosis Complex: Pathogenesis and Treatment ENSG00000100150 ENSG00000177169 ENSG00000196712 PMC2757648__F3 Interferon response genes are coordinately upregulated relative to the rs17445836 allele of IRF8 ENSG00000182578 ENSG00000188379 ENSG00000143546 ENSG00000163220 ENSG00000183486 ENSG00000115267 ENSG00000185745 ENSG00000116701 ENSG00000213341 ENSG00000276561 ENSG00000142166 ENSG00000077454 ENSG00000127445 ENSG00000136250 ENSG00000239732 ENSG00000066336 ENSG00000239998 ENSG00000163131 ENSG00000136869 ENSG00000140464 PMC10984535__F6 Pathway dynamics of islets during diabetes progression ENSG00000148408 ENSG00000137275 ENSG00000150907 ENSG00000163394 ENSG00000159399 PMC11354572__F1 Serum TLR2 and TLR9 in Prostate Cancer Patients in Relation to EBV Status ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000163568 ENSG00000163565 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC7943466__F4 General mechanism of MP formation, its mode of action, and the proposed possible impacts of diets on MPs that could be linked with CSVD ENSG00000163914 ENSG00000173599 ENSG00000162692 PMC10532491__F5 EGFR signal transduction pathway—an overview (modified after [94]) ENSG00000167601 ENSG00000157764 ENSG00000198793 ENSG00000121879 ENSG00000146648 ENSG00000139687 PMC3096494__F1 Regulation of Interleukin-10 Gene Expression in Macrophages Engulfing Apoptotic Cells ENSG00000170458 ENSG00000136869 ENSG00000185591 ENSG00000143995 PMC4061247__F3 Nuclear Trafficking in Health and Disease ENSG00000099901 PMC8502122__F1 Comprehensive method for determining cellular uptake of purine nucleoside phosphorylase and adenylosuccinate synthetase inhibitors by H. pylori ENSG00000146676 ENSG00000167701 PMC10532491__F2 Targeted EGFR Nanotherapy in Non-Small Cell Lung Cancer ENSG00000019991 ENSG00000163235 ENSG00000138798 ENSG00000146648 PMC10532491__F3 Targeted EGFR Nanotherapy in Non-Small Cell Lung Cancer ENSG00000115415 ENSG00000109321 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC3614848__F2 STRING interaction for proteins studied to find relevant networks in RCC ENSG00000134086 ENSG00000059804 ENSG00000089685 ENSG00000288174 ENSG00000128052 ENSG00000171791 ENSG00000112715 PMC11941256__F1 BMP signaling pathway ENSG00000163914 PMC7957592__F7 Influence of TP53 on FAM72 paralogs directly regulates the cell cycle in cancer ENSG00000132906 ENSG00000138794 ENSG00000101057 ENSG00000171791 ENSG00000164305 ENSG00000183765 ENSG00000149311 ENSG00000175054 ENSG00000103479 ENSG00000215784 ENSG00000198176 ENSG00000196550 ENSG00000188610 ENSG00000266028 ENSG00000123374 ENSG00000149554 ENSG00000139687 ENSG00000080839 ENSG00000282899 PMC9119177__F7 Cingulin b Is Required for Zebrafish Lateral Line Development Through Regulation of Mitogen-Activated Protein Kinase and Cellular Senescence Signaling Pathways ENSG00000149311 ENSG00000170458 ENSG00000102871 ENSG00000157601 ENSG00000105697 PMC5818912__F4 The ADAM17/EGFR axis ENSG00000148400 ENSG00000109321 ENSG00000146648 PMC3674623__F6 Effect of sodium ferulate on caspase cascade apoptosis and IKK/NFKB pathways induced by TNF/TNF receptor ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC5818912__F7 ADAM17/EGFR signaling an important player in CF and COPD lung disease ENSG00000109321 ENSG00000168610 ENSG00000146648 PMC5412308__F4 DEGs protein–protein interaction (PIP) network complex and modular analysis ENSG00000114200 ENSG00000121211 ENSG00000088002 ENSG00000145113 ENSG00000125398 ENSG00000203760 ENSG00000100170 ENSG00000078098 ENSG00000169174 ENSG00000143995 ENSG00000130513 ENSG00000133083 ENSG00000151882 ENSG00000179914 ENSG00000127955 ENSG00000163736 ENSG00000140297 ENSG00000117724 ENSG00000133048 ENSG00000180875 ENSG00000124253 ENSG00000166869 ENSG00000131153 ENSG00000166501 ENSG00000137673 ENSG00000151012 ENSG00000086991 ENSG00000169860 ENSG00000106483 ENSG00000133216 ENSG00000016490 ENSG00000134057 ENSG00000101255 ENSG00000156113 ENSG00000157404 ENSG00000119969 ENSG00000163737 ENSG00000093009 ENSG00000138778 ENSG00000159216 ENSG00000089685 ENSG00000110777 ENSG00000152217 ENSG00000095303 ENSG00000163734 ENSG00000139629 ENSG00000170231 ENSG00000121621 ENSG00000120729 ENSG00000196620 ENSG00000182580 ENSG00000109205 ENSG00000154175 ENSG00000162896 ENSG00000168447 ENSG00000123975 ENSG00000108231 ENSG00000181804 ENSG00000112964 ENSG00000070882 ENSG00000165891 ENSG00000164109 ENSG00000185479 ENSG00000165621 ENSG00000103375 ENSG00000112877 ENSG00000197565 ENSG00000100526 ENSG00000188175 ENSG00000166670 ENSG00000169432 ENSG00000126787 ENSG00000144354 ENSG00000148848 ENSG00000169715 ENSG00000139618 ENSG00000174992 ENSG00000158467 ENSG00000146670 ENSG00000119547 ENSG00000186184 ENSG00000117650 ENSG00000169607 ENSG00000039987 ENSG00000134827 ENSG00000109805 ENSG00000280610 ENSG00000115263 ENSG00000112984 ENSG00000171017 ENSG00000165376 ENSG00000198846 ENSG00000198125 ENSG00000282941 ENSG00000088992 ENSG00000115009 ENSG00000101670 ENSG00000169248 ENSG00000107562 ENSG00000165480 ENSG00000077152 ENSG00000163739 ENSG00000157193 ENSG00000124875 ENSG00000145386 ENSG00000101680 ENSG00000072571 ENSG00000206075 ENSG00000137265 ENSG00000163993 ENSG00000112742 ENSG00000111247 ENSG00000171320 ENSG00000086696 ENSG00000081041 ENSG00000277909 ENSG00000115163 ENSG00000184661 ENSG00000164171 ENSG00000143228 ENSG00000186871 ENSG00000171848 ENSG00000164398 ENSG00000176387 ENSG00000155850 ENSG00000176619 PMC3202828__F5 Cif hijacks several and various signaling pathways by inhibiting the ubiquitin ligase activity of CRL ENSG00000167513 ENSG00000168036 PMC6065367__F8 Proposed mechanism for TSPO ligand-induced ATP release ENSG00000112212 PMC12215448__F4 Interaction of CD8+ NKT-like cells, CD8+ T cells and GDT cells with NK cells ENSG00000117091 ENSG00000122223 ENSG00000028137 PMC5566109__F5 CircRNAs and the related signaling pathways in human cancers ENSG00000078747 ENSG00000168036 ENSG00000123374 ENSG00000105810 ENSG00000171608 ENSG00000146648 PMC9607849__F1 Development of a Chiral Supercritical Fluid Chromatography–Tandem Mass Spectrometry and Reversed-Phase Liquid Chromatography–Tandem Mass Spectrometry Platform for the Quantitative Metabolic Profiling of Octadecanoid Oxylipins ENSG00000179148 PMC11953509__F7 NEK2 promotes cancer cell progression and 5-fluorouracil resistance via the Wnt/Beta-catenin signaling pathway in colorectal cancer ENSG00000117650 ENSG00000134982 ENSG00000168036 PMC8660639__F7 Proposed mechanistic scheme of PCID2 in promoting the canonical Wnt signaling pathway in colorectal cancer ENSG00000168036 ENSG00000126226 ENSG00000140464 PMC3724648__F6 Model showing the effects of PP2A in SLE T-cells ENSG00000120690 ENSG00000185591 PMC5964874__F4 MicroRNA sequence analysis identifies microRNAs associated with peri-implantitis in dogs ENSG00000087095 ENSG00000172680 ENSG00000170458 ENSG00000130522 ENSG00000138798 ENSG00000166278 ENSG00000130159 ENSG00000175104 ENSG00000127191 ENSG00000146648 ENSG00000081189 ENSG00000026103 PMC4571158__F2 A schematic presentation of secreted, endocytic, and signaling pattern-recognition receptors ENSG00000244731 ENSG00000166278 ENSG00000236625 PMC11671673__F8 Schematic diagram about working model of YTHDC1 ENSG00000145592 ENSG00000275272 ENSG00000107581 PMC6345383__F2 PDA cells have a remarkable ability to adapt to nutrient fluctuations and targeted therapies ENSG00000125166 ENSG00000065833 ENSG00000115419 PMC12068294__F2 Bioactivities of stem cells cultured on fish-derived biomaterials ENSG00000136869 ENSG00000125245 PMC5454963__F1 Proposed action mechanisms of glutamine in intestinal cells ENSG00000138378 ENSG00000115415 ENSG00000198793 ENSG00000168610 PMC4148147__F7 Ebolavirus VP35 suppresses IFN production from conventional but not plasmacytoid dendritic cells ENSG00000088888 ENSG00000057593 ENSG00000172936 ENSG00000131323 ENSG00000276561 ENSG00000184216 PMC9406534__F3 TNF Receptor Associated Factor 2 (TRAF2) Signaling in Cancer ENSG00000183735 ENSG00000088888 ENSG00000127191 PMC3617098__F1 Aag DNA Glycosylase Promotes Alkylation-Induced Tissue Damage Mediated by Parp1 ENSG00000143799 ENSG00000138385 PMC3620319__F3 An Integrated Approach to Uncover Driver Genes in Breast Cancer Methylation Genomes ENSG00000127191 ENSG00000282899 PMC10937645__F8 Proposed model of the recognition of bacteriophage DNA by the animal immune system ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000172936 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC6378054__F1 UPR signaling cascade ENSG00000128272 ENSG00000144895 ENSG00000115419 PMC9406534__F2 TNF Receptor Associated Factor 2 (TRAF2) Signaling in Cancer ENSG00000104856 ENSG00000112186 ENSG00000127191 PMC10305623__F1 11-oxygenated androgens in prostate cancer ENSG00000086696 ENSG00000151632 ENSG00000277893 ENSG00000173599 ENSG00000203857 PMC4922205__F2 BCR-ABL1 Signaling Network ENSG00000145604 ENSG00000033327 ENSG00000186716 ENSG00000198793 ENSG00000121058 PMC3076281__F2 Sphingolipid effects on intrinsic and extrinsic apoptotic pathways ENSG00000002330 ENSG00000102871 ENSG00000168040 ENSG00000026103 PMC3076281__F3 Effect of sphingolipids on the PI3K/AKT pathway ENSG00000132906 ENSG00000002330 ENSG00000198793 PMC6274856__F1 Cartoon showing the major signaling pathways targeted by phytochemicals in cancer ENSG00000198793 PMC6862031__F5 Summary of altered metabolic pathways and regulatory mechanism of rFIP-nha against A549 cells ENSG00000135423 ENSG00000198793 ENSG00000078237 ENSG00000284194 PMC7856101__F2 Gut Microbiota in Epigenetic Regulation of Colorectal Cancer ENSG00000168036 ENSG00000136869 ENSG00000168610 PMC7926694__F6 Emerging effect of ferroptosis in malaria immunity ENSG00000135423 ENSG00000151012 ENSG00000167468 ENSG00000115107 PMC9283764__F4 Lung Alveolar Cell (LAC) miRNome and Gene Expression Profile of the SP-A-KO Mice After Infection With and Without Rescue With Human Surfactant Protein-A2 (1A0) ENSG00000138778 ENSG00000099940 ENSG00000119396 ENSG00000126264 ENSG00000138760 ENSG00000106546 ENSG00000132170 PMC8065509__F2 LTBR signaling pathway in lymphatic endothelial cell (LEC) ENSG00000102871 ENSG00000111321 ENSG00000131323 ENSG00000127191 PMC3627549__F6 Decreased Hepatotoxic Bile Acid Composition and Altered Synthesis in Progressive Human Nonalcoholic Fatty Liver Disease ENSG00000276559 ENSG00000180432 ENSG00000099377 ENSG00000115271 ENSG00000122787 ENSG00000135929 PMC6098968__F1 Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums ENSG00000132906 ENSG00000142192 ENSG00000002330 ENSG00000198793 ENSG00000169047 ENSG00000177606 ENSG00000136997 ENSG00000168036 ENSG00000164327 PMC9036297__F4 Uncovering Novel Pre-Treatment Molecular Biomarkers for Anti-TNF Therapeutic Response in Patients with Crohn’s Disease ENSG00000002330 ENSG00000173156 PMC3736540__F1 Computational Model of Lipopolysaccharide-Induced Nuclear Factor Kappa B Activation: A Key Signalling Pathway in Infection-Induced Preterm Labour ENSG00000172936 ENSG00000136869 PMC5580529__F3 Proposed model for the regulation of synaptic restructuring by Wnt during learning (from ) ENSG00000134982 ENSG00000168036 PMC8385607__F5 Pima Indian Contributions to Our Understanding of Diabetic Kidney Disease ENSG00000172216 ENSG00000095321 ENSG00000198793 ENSG00000137193 PMC7532113__F1 ERBB family comprises four receptor tyrosine kinases including the epidermal growth factor receptor (EGFR) ENSG00000198793 ENSG00000140443 PMC8746762__F12 The mechanism behind the inhibition of the TGF-Alpha-induced HCC cell migration by raloxifene and bazedoxifene ENSG00000163235 ENSG00000146648 PMC11901933__F8 Reparative potential of LF in UVB-exposed HaCaT cells ENSG00000170961 PMC3666377__F3 Functional Beta-cells respond to increasing glucose levels by increasing insulin secretion ENSG00000135100 ENSG00000107249 ENSG00000139515 ENSG00000049768 ENSG00000168267 ENSG00000138160 ENSG00000185002 ENSG00000106331 PMC9240200__F2 Vicious Cycle: In Severe and Critically Ill COVID-19 Patients ENSG00000130234 ENSG00000136869 ENSG00000168610 PMC7336871__F2 Physical approximation of APP and BACE-1 - a key event in Alzheimer’s disease pathogenesis ENSG00000143553 ENSG00000142192 ENSG00000175115 ENSG00000143376 ENSG00000198087 ENSG00000133961 ENSG00000110025 ENSG00000114520 PMC8888693__F1 Using a Systems Approach to Explore the Mechanisms of Interaction Between Severe Covid-19 and Its Coronary Heart Disease Complications ENSG00000162692 ENSG00000005469 PMC3319201__F3 Primary therapeutic targets in the Ras downstream signaling pathway ENSG00000186575 ENSG00000198793 ENSG00000163914 ENSG00000196712 PMC12104164__F3 Signaling pathways related to fibrocartilageThe complex network of interrelated signaling pathways is involved in the generation of fibrocartilage, including TGFB/SMAD, WNT/Beta-catenin, Hippo, PI3K/AKT, and NFKB ENSG00000138795 ENSG00000198793 ENSG00000121058 ENSG00000197905 ENSG00000173039 ENSG00000168036 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC3559989__F6 Bayesian regulatory network and optimal regulatory pathway of p42.3 protein ENSG00000134086 ENSG00000163914 ENSG00000196154 ENSG00000185591 ENSG00000067900 PMC7946937__F4 Rewired signal pathways by deregulated Myc in cancer and its related components available for synthetic lethality ENSG00000106245 ENSG00000100219 ENSG00000253729 PMC4837572__F3 Synaptic transmission: lipid-protein interactions ENSG00000070831 ENSG00000291971 ENSG00000107130 PMC8491037__F1 Triacylglycerol remodeling in Physaria fendleri indicates oil accumulation is dynamic and not a metabolic endpoint ENSG00000173599 ENSG00000198670 ENSG00000173402 PMC8495584__F3 Research progress on evodiamine, a bioactive alkaloid of Evodiae fructus: Focus on its anti-cancer activity and bioavailability (Review) ENSG00000198793 ENSG00000168610 PMC4707441__F2 Tetraspanins organize the T-cell immunological synapse ENSG00000085117 ENSG00000134982 ENSG00000163914 ENSG00000110651 ENSG00000010278 ENSG00000104368 PMC5378187__F2 Plant-parasitic nematodes: towards understanding molecular players in stress responses ENSG00000105227 PMC4197207__F3 PRR signaling in testicular cells ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC8491037__F7 Triacylglycerol remodeling in Physaria fendleri indicates oil accumulation is dynamic and not a metabolic endpoint ENSG00000173599 ENSG00000198670 PMC10723546__F3 Biological pathways in ccRCC ENSG00000152266 ENSG00000163939 ENSG00000005339 ENSG00000157764 ENSG00000198793 ENSG00000181555 ENSG00000154582 ENSG00000169032 ENSG00000116251 ENSG00000276043 ENSG00000117713 ENSG00000149311 ENSG00000175054 ENSG00000136878 ENSG00000134086 ENSG00000074266 ENSG00000178691 ENSG00000127616 ENSG00000198625 ENSG00000189079 ENSG00000109670 PMC8024119__F5 Enhanced activity of the RAS-MAPK signaling pathway due to the loss-of-function mutation of the NF1 gene and mode of selumetinib action ENSG00000157764 ENSG00000196712 PMC9185151__F1 InterferonA and its effects on cancer cell apoptosis ENSG00000213928 ENSG00000105397 ENSG00000115415 PMC5590790__F1 Molecular mechanism underlying cardiovascular diseases associated with the changing of intracellular Ca2+ through TRPCs ENSG00000042832 ENSG00000137672 ENSG00000138741 PMC3661940__F1 Intrinsic somatodendritic and presynaptic modulation of action potential (AP) firing and transmitter release in 5-HT neurons ENSG00000128310 ENSG00000168329 ENSG00000182687 PMC8431803__F1 Chlorpyrifos Disrupts Acetylcholine Metabolism Across Model Blood-Brain Barrier ENSG00000144410 ENSG00000197408 ENSG00000087085 PMC5445933__F3 Main pathways altered in GEMMs of cutaneous melanoma ENSG00000019991 ENSG00000198793 ENSG00000123374 PMC6338564__F5 Proline Metabolism in Cell Regulation and Cancer Biology: Recent Advances and Hypotheses ENSG00000105835 ENSG00000136997 ENSG00000100033 ENSG00000096717 ENSG00000115419 PMC6338564__F6 Proline Metabolism in Cell Regulation and Cancer Biology: Recent Advances and Hypotheses ENSG00000149311 ENSG00000136997 PMC4641522__F4 Paradigm for testing the multiple independent mechanisms that reinforce IDO1-mediated immunosuppression in malignant glioma ENSG00000134982 ENSG00000150907 ENSG00000188676 PMC8082504__F10 Xiaoyao Pills Ameliorate Depression-like Behaviors and Oxidative Stress Induced by Olfactory Bulbectomy in Rats via the Activation of the PIK3CA-AKT1-NFE2L2/BDNF Signaling Pathway ENSG00000211445 ENSG00000150782 ENSG00000116044 ENSG00000121879 PMC5154770__F1 Naïve T cells are predominantly oxidative and constantly monitor their environment for immune insult ENSG00000198793 ENSG00000136997 ENSG00000164136 PMC7793984__F1 LMP agents and biological factors that induce lysosomal rupture and cell death ENSG00000173599 ENSG00000005893 ENSG00000141458 PMC3047044__F1 Simplified schematic version of the epidermal growth factor receptor (EGFR) signaling cascade ENSG00000157764 ENSG00000163235 ENSG00000138798 ENSG00000146648 PMC2817383__F4 Putative host signaling pathway induced by Y ENSG00000280962 ENSG00000137033 ENSG00000172936 ENSG00000128342 ENSG00000148344 ENSG00000168610 ENSG00000135517 PMC6423493__F5 GRP78 mediates hypoxia-induced EMT through smad2/3 and SRC/MAPK signaling ENSG00000291971 PMC9085754__F4 MALAT1 as master regulator of biomarkers predictive of pan-cancer multi-drug resistance in the context of recalcitrant NRAS signaling pathway identified using systems-oriented approach ENSG00000087510 ENSG00000245848 ENSG00000159216 ENSG00000109320 ENSG00000130522 ENSG00000113140 ENSG00000173039 ENSG00000026508 ENSG00000107485 ENSG00000185591 ENSG00000251493 ENSG00000162599 PMC6251060__F1 Autophagy: A Lysosome-Dependent Process with Implications in Cellular Redox Homeostasis and Human Disease ENSG00000177169 ENSG00000110497 ENSG00000152348 ENSG00000123395 ENSG00000198382 ENSG00000144848 ENSG00000155792 ENSG00000171791 ENSG00000145782 ENSG00000057663 ENSG00000136874 PMC6715306__F1 Extrinsic and intrinsic cues regulate the oligodendrocyte program ENSG00000100811 ENSG00000184221 ENSG00000197971 ENSG00000010810 ENSG00000198793 ENSG00000163914 ENSG00000134853 ENSG00000164690 ENSG00000273529 ENSG00000100146 ENSG00000196628 ENSG00000172201 PMC6251060__F4 Autophagy: A Lysosome-Dependent Process with Implications in Cellular Redox Homeostasis and Human Disease ENSG00000158828 ENSG00000069509 ENSG00000171109 PMC4947555__F3 Histological chorioamnionitis shapes the neonatal transcriptomic immune response ENSG00000182718 ENSG00000066336 ENSG00000092067 ENSG00000292210 PMC8898355__F1 Ferroptosis by Amino Acid Metabolism in Cancer ENSG00000182511 ENSG00000167468 ENSG00000198793 PMC9370123__F2 Cerebral Folate Deficiency Syndrome: Early Diagnosis, Intervention and Treatment Strategies ENSG00000139287 ENSG00000035928 PMC6042401__F8 Alterations in CREB signaling ENSG00000101751 ENSG00000166169 PMC7391667__F3 Direct pathway of m6A to regulate transcriptome a Two possible mechanisms of eIF3 regulating mRNA translation initiation ENSG00000145388 ENSG00000163435 ENSG00000149658 ENSG00000198492 ENSG00000047188 ENSG00000174197 ENSG00000275272 PMC8638425__F4 Insights into high-risk multiple myeloma from an analysis of the role of PHF19 in cancer ENSG00000129757 ENSG00000163818 ENSG00000119403 ENSG00000108799 ENSG00000136997 ENSG00000143839 ENSG00000107902 ENSG00000074266 ENSG00000171791 ENSG00000178691 ENSG00000124762 PMC7510328__F2 MET and/or RON activation, signaling pathway, and biological consequence ENSG00000019991 ENSG00000134086 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000171791 ENSG00000146648 ENSG00000140443 PMC3744227__F1 Chemopreventive potential of natural compounds in head and neck cancer ENSG00000138798 ENSG00000198793 ENSG00000173039 ENSG00000168036 ENSG00000146648 PMC6409601__F4 Hypermodification of m5C34 in anticodon of cytoplasmic and mitochondrial tRNAs ENSG00000178694 ENSG00000037474 ENSG00000068438 PMC2666381__F1 TLR signaling and the role of epithelium in corneal innate defense ENSG00000226275 ENSG00000239732 ENSG00000187554 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC9622788__F1 Regulatory necrosis in traumatic brain injury ENSG00000065833 ENSG00000102871 ENSG00000198576 ENSG00000083799 ENSG00000168404 ENSG00000127191 ENSG00000101421 PMC9622788__F2 Regulatory necrosis in traumatic brain injury ENSG00000278718 ENSG00000162711 ENSG00000130234 ENSG00000163568 ENSG00000125538 ENSG00000136869 ENSG00000247077 PMC4870750__F8 Seasonal bias in toll-like receptor (TLR) signalling pathway ENSG00000104365 ENSG00000137275 ENSG00000109320 ENSG00000269335 ENSG00000255690 ENSG00000169032 ENSG00000168040 ENSG00000150455 ENSG00000135341 ENSG00000121879 ENSG00000276561 ENSG00000143387 ENSG00000183735 ENSG00000239732 ENSG00000185386 ENSG00000118785 ENSG00000187554 ENSG00000263528 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC4260725__F2 Major signaling pathway regulation and core machinery of autophagy ENSG00000152348 ENSG00000123395 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC9622788__F4 Regulatory necrosis in traumatic brain injury ENSG00000278718 ENSG00000102871 ENSG00000285379 PMC1064894__F3 Toll-like receptor (TLR) signaling pathways ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC10380946__F3 Involvement of Polyunsaturated Fatty Acids in Apoptosis Mechanisms and Their Implications in Cancer ENSG00000002330 ENSG00000102871 ENSG00000198793 ENSG00000120868 ENSG00000281879 ENSG00000168040 ENSG00000127191 ENSG00000146648 ENSG00000026103 PMC12066790__F10 Oncogenic mechanisms of HTLV-1 in adult T-cell leukemia/lymphoma ENSG00000089692 ENSG00000181847 ENSG00000089685 ENSG00000132646 ENSG00000130656 ENSG00000136997 ENSG00000137265 ENSG00000049768 ENSG00000168610 ENSG00000112130 ENSG00000198286 ENSG00000109670 PMC10380946__F4 Illustrates the apoptosis mechanisms triggered by DHA ENSG00000002330 ENSG00000102871 ENSG00000198793 ENSG00000168040 ENSG00000140961 ENSG00000168610 ENSG00000115884 ENSG00000128272 ENSG00000144895 ENSG00000136869 ENSG00000100219 ENSG00000120868 ENSG00000146648 ENSG00000026103 PMC10380946__F1 Involvement of Polyunsaturated Fatty Acids in Apoptosis Mechanisms and Their Implications in Cancer ENSG00000002330 ENSG00000120868 PMC6899527__F3 Single-Cell Sequencing of ChAT/vAChT-Positive Cortical Cells and Analysis of Their Expressed TranscriptsExpression values were normalized (0–1) for each dataset ENSG00000114200 ENSG00000184221 ENSG00000087085 ENSG00000167281 ENSG00000064300 ENSG00000274542 ENSG00000187714 ENSG00000106852 ENSG00000133019 ENSG00000164900 ENSG00000162624 ENSG00000122756 ENSG00000274089 ENSG00000128342 ENSG00000168505 ENSG00000120903 ENSG00000080644 ENSG00000117971 ENSG00000180720 ENSG00000147432 ENSG00000242689 ENSG00000147434 ENSG00000146469 ENSG00000131095 ENSG00000136352 ENSG00000157005 ENSG00000016082 ENSG00000206561 ENSG00000105397 PMC10380946__F2 Involvement of Polyunsaturated Fatty Acids in Apoptosis Mechanisms and Their Implications in Cancer ENSG00000188486 ENSG00000002330 ENSG00000120868 ENSG00000168040 ENSG00000026103 PMC10380946__F7 ARA on apoptotic death pathways ENSG00000144895 ENSG00000120868 ENSG00000168040 ENSG00000026103 PMC8187247__F1 Antiviral strategies targeting herpesviruses ENSG00000130202 ENSG00000197461 PMC10380946__F5 Involvement of Polyunsaturated Fatty Acids in Apoptosis Mechanisms and Their Implications in Cancer ENSG00000002330 ENSG00000120868 ENSG00000168040 ENSG00000026103 PMC10380946__F6 Involvement of Polyunsaturated Fatty Acids in Apoptosis Mechanisms and Their Implications in Cancer ENSG00000002330 ENSG00000120868 PMC6216032__F4 Smad-dependent/independent transforming growth factor-beta signaling pathways ENSG00000162772 PMC10531214__F3 Exploring the JAK/STAT Signaling Pathway in Hepatocellular Carcinoma: Unraveling Signaling Complexity and Therapeutic Implications ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000173757 ENSG00000105639 ENSG00000168610 PMC10531214__F4 Exploring the JAK/STAT Signaling Pathway in Hepatocellular Carcinoma: Unraveling Signaling Complexity and Therapeutic Implications ENSG00000128342 ENSG00000162892 ENSG00000142224 PMC10295928__F6 MiRNA-assisted immunotherapy ENSG00000277943 PMC11625190__F1 Biosynthetic pathway of 1-phenylethylisoquinoline-derived PIAs ENSG00000196344 PMC10295928__F5 MiRNA-assisted targeted therapy ENSG00000167601 ENSG00000019991 ENSG00000118785 ENSG00000198793 ENSG00000169047 ENSG00000196591 ENSG00000026508 ENSG00000164690 ENSG00000146648 ENSG00000140443 PMC6965651__F8 ADT-OH, a hydrogen sulfide-releasing donor, induces apoptosis and inhibits the development of melanoma in vivo by upregulating FADD ENSG00000133606 ENSG00000168040 ENSG00000164305 PMC3601164__F3 Links between Toll-like receptor 4 and breast cancer ENSG00000183735 ENSG00000172936 ENSG00000136869 ENSG00000131323 PMC8488570__F3 The CCL2‐CCR2 signalling axis in cancer: Mechanisms and therapeutic targeting ENSG00000108691 ENSG00000198793 ENSG00000121807 ENSG00000168610 PMC4277955__F1 Interleukin-22 signaling pathway ENSG00000105397 ENSG00000168610 PMC3601164__F2 Links between Toll-like receptor 4 and breast cancer ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC8909150__F1 Genomic and Epigenomic Landscape of Juvenile Myelomonocytic Leukemia ENSG00000033327 ENSG00000110395 ENSG00000196712 PMC11976435__F1 Wnt/Beta-Catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11851563__F2 Beta-Catenin and DNA repair pathways ENSG00000012061 ENSG00000143799 ENSG00000165556 ENSG00000101057 ENSG00000126457 ENSG00000168036 ENSG00000196470 ENSG00000057294 ENSG00000196628 ENSG00000139618 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000163251 ENSG00000113318 ENSG00000132646 ENSG00000170430 ENSG00000139372 ENSG00000189403 ENSG00000051180 ENSG00000095002 ENSG00000136936 ENSG00000175792 ENSG00000122512 PMC8600818__F9 Nickel nanoparticle-induced cell transformation: involvement of DNA damage and DNA repair defect through HIF-1A/miR-210/Rad52 pathway ENSG00000188486 ENSG00000149311 PMC6071762__F1 Biosynthesis of glycerophospholipids and sphingolipids in mammalian cells ENSG00000173599 ENSG00000184207 PMC6658087__F9 Sulforaphane enriched transcriptome of lung mitochondrial energy metabolism and provided pulmonary injury protection via Nrf2 in mice ENSG00000265354 ENSG00000143158 ENSG00000179091 ENSG00000288174 ENSG00000079999 ENSG00000130304 ENSG00000177542 ENSG00000173992 ENSG00000182902 ENSG00000139209 ENSG00000116688 ENSG00000242114 ENSG00000175768 ENSG00000120675 ENSG00000105197 ENSG00000122696 ENSG00000159399 ENSG00000060762 ENSG00000062485 PMC6293111__F6 Model depicting the molecular function of Lsm12 ENSG00000132646 ENSG00000130997 ENSG00000161654 PMC11851563__F1 Canonical Wnt signaling pathway ENSG00000134982 ENSG00000168036 PMC6071762__F5 Apparent unidirectional fluxes of the LTP-mediated inter-organelle transport of lipids are indirectly coupled with metabolic reactions of lipids ENSG00000173599 ENSG00000110048 PMC11976435__F2 Non-canonical Wnt signaling pathway ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000100592 ENSG00000146122 PMC6658087__F5 Sulforaphane enriched transcriptome of lung mitochondrial energy metabolism and provided pulmonary injury protection via Nrf2 in mice ENSG00000152661 ENSG00000138443 ENSG00000175592 ENSG00000012048 ENSG00000144802 ENSG00000136997 ENSG00000185591 ENSG00000125810 ENSG00000128342 ENSG00000132681 ENSG00000179348 ENSG00000090376 ENSG00000100906 ENSG00000269335 ENSG00000162924 ENSG00000177663 ENSG00000168610 ENSG00000007171 ENSG00000065978 ENSG00000124216 ENSG00000111537 ENSG00000072694 ENSG00000143322 ENSG00000154188 ENSG00000112115 ENSG00000150630 PMC3108205__F4 Delay in apoptosis at 9 hr ENSG00000142192 ENSG00000002330 ENSG00000084774 ENSG00000115317 ENSG00000026103 PMC4909382__F7 Schematic depiction of the antiapoptotic conditions including the PRL signaling pathway in young RPE versus the proapoptotic conditions in aging RPE ENSG00000197713 ENSG00000113494 ENSG00000283100 PMC3720859__F4 Capacity of Aptamers to Trigger Immune Activation in Human Blood ENSG00000142192 ENSG00000172936 ENSG00000150455 PMC2920202__F2 Spatial-temporal signals determine the fate of activated CD8+ T cells ENSG00000139193 ENSG00000164136 PMC2785495__F3 Response of heterogeneous ribonuclear proteins (hnRNP) to ionizing radiation and their involvement in DNA damage repair ENSG00000149311 ENSG00000175054 ENSG00000165119 PMC3490606__F1 Reactions involved in the flux of fatty acids into ENSG00000173599 ENSG00000198670 ENSG00000026103 PMC1855986__F9 ATM-Mediated Transcriptional and Developmental Responses to Gamma-rays in Arabidopsis ENSG00000149311 ENSG00000175054 PMC8013731__F8 Toll-like receptor signaling pathway and NF-kappa B signaling pathway regulated by the S100s alteration in HCC ENSG00000144410 ENSG00000170458 ENSG00000105656 ENSG00000168040 ENSG00000164342 ENSG00000143387 PMC2833340__F1 Plane facts of PCP in the CNS ENSG00000175054 ENSG00000164932 ENSG00000169071 ENSG00000070831 ENSG00000112655 PMC6689252__F6 Extinction-dependent network of genes in morphine-treated rats ENSG00000134020 ENSG00000078549 ENSG00000291873 ENSG00000108960 ENSG00000116329 ENSG00000162924 ENSG00000149295 ENSG00000185652 ENSG00000169291 ENSG00000171777 ENSG00000196371 ENSG00000036530 ENSG00000168546 ENSG00000185532 ENSG00000132326 ENSG00000188611 ENSG00000138741 ENSG00000177684 ENSG00000095794 ENSG00000134258 ENSG00000227345 ENSG00000136068 ENSG00000099904 PMC3219092__F3 Nox regulation of the PI3K/AKT pathway ENSG00000002330 ENSG00000291971 ENSG00000150907 PMC6757184__F1 Wnt/Beta-catenin signaling as a useful therapeutic target in hepatoblastoma ENSG00000138798 ENSG00000168036 ENSG00000111371 PMC3825518__F1 From Evolution to Revolution: miRNAs as Pharmacological Targets for Modulating Cholesterol Efflux and Reverse Cholesterol Transport ENSG00000130164 ENSG00000042832 ENSG00000160179 PMC4284388__F3 Platelet signaling induced by GPIb-IX-V and required for AIIbB3 activation ENSG00000124102 ENSG00000110799 ENSG00000291971 ENSG00000197943 PMC4172484__F7 Amygdala-dependent fear memory consolidation via miR-34a and Notch signaling ENSG00000114315 PMC4882019__F3 Temporal Expression of Peripheral Blood Leukocyte Biomarkers in a Macaca fascicularis Infection Model of Tuberculosis; Comparison with Human Datasets and Analysis with Parametric/Non-parametric Tools for Improved Diagnostic Biomarker Identification ENSG00000023445 ENSG00000177575 ENSG00000113889 ENSG00000106066 ENSG00000115415 ENSG00000163736 ENSG00000125810 ENSG00000164305 PMC8901678__F1 Hepatic glucose, lipids, and amino acid metabolism ENSG00000065833 ENSG00000042832 ENSG00000198793 ENSG00000172005 PMC8901678__F2 Systemic iron homeostasis PMC8901678__F3 Iron metabolism in the liver ENSG00000121989 ENSG00000164077 ENSG00000010704 ENSG00000106327 ENSG00000147454 ENSG00000118564 ENSG00000187045 ENSG00000178752 ENSG00000168610 ENSG00000115107 ENSG00000204217 PMC4518307__F5 Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst ENSG00000180210 ENSG00000168003 ENSG00000125166 ENSG00000160883 ENSG00000183048 ENSG00000010379 ENSG00000087299 ENSG00000111181 ENSG00000169299 PMC8037590__F1 PI3K and MAPK signalling pathways ENSG00000002330 ENSG00000198793 ENSG00000155792 ENSG00000164327 PMC8037590__F2 Insulin-mediated feedback loops following PI3K/mTOR inhibition ENSG00000198793 ENSG00000155792 PMC8387356__F1 Influence of diets on metabolites and the epigenetic machinery ENSG00000198901 ENSG00000147162 ENSG00000198408 ENSG00000156531 PMC2804114__F1 IR and IGF family signaling pathway ENSG00000198793 PMC7696079__F2 Underlying mechanisms of LND-mediated antitumor activity ENSG00000143252 ENSG00000073578 PMC6888321__F3 Cell signaling pathways activated in osteogenesis and angiogenesis models: Wingless-related integration site (Wnt) pathway, bone morphogenetic protein (BMP) pathway, and fibroblast growth factor (FGF)/platelet-derived growth factor (PDGF) pathway ENSG00000170365 ENSG00000168036 ENSG00000146197 PMC6748367__F6 KEGG Pathview readouts of DEX vs Control-associated differential gene expression ENSG00000134982 ENSG00000121879 ENSG00000146648 PMC8633576__F13 Costunolide-Induced Apoptosis via Promoting the Reactive Oxygen Species and Inhibiting AKT/GSK3B Pathway and Activating Autophagy in Gastric Cancer ENSG00000143799 PMC6468357__F4 FOXK2 role as an oncogene in cancer ENSG00000125398 ENSG00000168036 ENSG00000141568 ENSG00000038002 PMC8640960__F3 Molecular Characterization of Limited Ulcerative Colitis Reveals Novel Biology and Predictors of Disease Extension ENSG00000128713 ENSG00000154269 ENSG00000121207 ENSG00000142973 ENSG00000138755 ENSG00000006327 ENSG00000135929 ENSG00000154096 ENSG00000119535 ENSG00000137033 ENSG00000108342 ENSG00000166670 ENSG00000169715 ENSG00000179520 ENSG00000169245 ENSG00000197576 ENSG00000134013 ENSG00000185201 ENSG00000164093 ENSG00000110944 ENSG00000125144 ENSG00000125538 ENSG00000087250 ENSG00000123610 ENSG00000115008 ENSG00000099985 ENSG00000197757 ENSG00000106006 ENSG00000275190 ENSG00000197375 ENSG00000180806 ENSG00000091138 ENSG00000197165 ENSG00000197208 ENSG00000168610 ENSG00000165794 ENSG00000203857 ENSG00000076351 ENSG00000162040 ENSG00000166401 ENSG00000172183 ENSG00000203972 ENSG00000124568 ENSG00000128710 ENSG00000108691 ENSG00000174358 ENSG00000125820 ENSG00000111537 ENSG00000174279 ENSG00000196502 ENSG00000175329 ENSG00000148942 ENSG00000104808 ENSG00000139540 ENSG00000165125 ENSG00000164756 ENSG00000187758 ENSG00000144290 ENSG00000128709 ENSG00000170178 ENSG00000150630 PMC10740672__F10 Oncogenic signaling pathway plays a crucial role in tumor suppression in vivo ENSG00000149311 ENSG00000175054 PMC12220104__F2 Activation of the IL-11 autocrine loop: TGFB acts on the TGFB receptor on the cell membrane, phosphorylating Smad2/3 in the cytoplasm ENSG00000163739 ENSG00000137070 ENSG00000198793 ENSG00000168036 ENSG00000124875 ENSG00000168610 ENSG00000115009 PMC3820452__F4 Working model for the proliferative, prosurvival, and migratory roles of TRPM8 in pancreatic adenocarcinoma cells ENSG00000138798 ENSG00000146648 ENSG00000084774 PMC3820452__F2 Working model for the signaling mechanisms that mediate the cellular functions of TRPM7 in pancreatic adenocarcinoma ENSG00000092439 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC2838317__F8 Differences between TRAIL- and AD5-10-induced signaling pathways ENSG00000168040 PMC12003952__F1 PLEVPs hydrogel alleviates psoriasis by modulating the IL-17 signaling pathway ENSG00000049768 PMC4251736__F4 Disorders of the PI3K-AKT-PTEN pathway ENSG00000117020 ENSG00000105647 ENSG00000121879 PMC9320947__F1 Contemporary Concise Review 2021: Interstitial lung disease ENSG00000137673 ENSG00000074181 ENSG00000108821 PMC2832838__F1 CONVERTING HUMAN PLURIPOTENT STEM CELLS INTO BETA CELLS: RECENT ADVANCES AND FUTURE CHALLENGES ENSG00000164736 ENSG00000125398 ENSG00000138798 ENSG00000139515 ENSG00000156574 ENSG00000182759 ENSG00000168267 ENSG00000121966 PMC7716236__F3 Metabolic variations in the course of NB4 differentiation along the myeloid lineage after treatment with ATRA ENSG00000112977 ENSG00000073578 ENSG00000141086 ENSG00000165264 PMC10532319__F7 Isolinderalactone Induces Apoptosis, Autophagy, Cell Cycle Arrest and MAPK Activation through ROS–Mediated Signaling in Colorectal Cancer Cell Lines ENSG00000132906 ENSG00000123374 ENSG00000145386 ENSG00000164305 PMC7166192__F3 Process of ferroptosis ENSG00000138449 ENSG00000167468 ENSG00000072274 ENSG00000111684 ENSG00000042286 ENSG00000110911 PMC11481463__F1 Critical role of IET as a drug precursor and the metabolic pathways relating to IET biosynthesis in S PMC8039950__F3 Function and underlying mechanisms of sialylated IgG (s-IgG) in myeloid and B cells ENSG00000239732 ENSG00000137033 ENSG00000186716 ENSG00000184371 ENSG00000105656 PMC6977602__F5 FSS regulating osteoclasts bone resorption function via ERK5 signaling pathway (green arrows are positively adjusted; red arrows are negatively adjusted; red lines are decreased due to inhibition of upstream proteins) ENSG00000100985 ENSG00000131196 ENSG00000143387 PMC3181038__F1 Signaling the unfolded protein response: Three proximal sensors IRE1, PERK, and ATF6 regulate the UPR through their respective signaling cascades ENSG00000128272 ENSG00000100219 PMC8124588__F1 Anaphylaxis: Focus on Transcription Factor Activity ENSG00000102145 ENSG00000157404 ENSG00000183695 ENSG00000112561 ENSG00000107485 ENSG00000145777 ENSG00000179348 ENSG00000168610 PMC6628023__F5 Schematic illustration of the molecular pathway of AhR and its effects on FSHR and survival ENSG00000106546 PMC2766922__F2 Signaling pathways downstream of HVEM, LIGHT, and their binding partners are shown ENSG00000186716 ENSG00000131323 ENSG00000127191 PMC3185585__F1 Remodeling the cellular secretory pathway to support enterovirus replication ENSG00000107862 ENSG00000143761 ENSG00000129744 PMC3057180__F1 Backup DNA repair pathway ENSG00000012048 ENSG00000138385 ENSG00000122678 PMC2840158__F6 Schematic showing cytoplasmic signaling pathway from ATM to TSC2 via LKB1 and AMPK to repress mTORC1 and induce autophagy ENSG00000149311 ENSG00000198793 PMC3431500__F1 Class I PI3K signal transduction pathway PMC4369255__F1 Synthesis and mechanisms of gaseous neurotransmitters in the relaxation of penile or other vascular tissues ENSG00000163914 PMC3414739__F2 LECA Rabs and their proposed functions ENSG00000169228 ENSG00000118508 ENSG00000157869 ENSG00000112210 ENSG00000080371 ENSG00000099246 ENSG00000119396 PMC7652848__F2 Aryl hydrocarbon receptor (AhR) signaling pathway and tryptophan-indoleamine 2,3-dioxygenase (IDO)-AhR axis ENSG00000110711 ENSG00000106546 PMC4130149__F1 An integrative overview of intracellular signaling pathways by the IL-1R, TLRs, NLRs, and CLRs upon an innate immune response to microbial infection or cell death ENSG00000162711 ENSG00000172936 ENSG00000136869 PMC4130149__F4 Schematic overview of TNF-Alpha-induced signaling pathways to activation of NFKB (a), apoptosis (b), and necroptosis (c) ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC5316486__F3 Transposon mutagenesis identifies candidate genes that cooperate with loss of Transforming Growth Factor-beta signaling in mouse intestinal neoplasms ENSG00000107779 ENSG00000121989 ENSG00000140992 ENSG00000132323 ENSG00000157933 ENSG00000281324 ENSG00000005339 ENSG00000141551 ENSG00000111859 ENSG00000133056 ENSG00000162337 ENSG00000134982 ENSG00000134308 ENSG00000150093 ENSG00000091409 ENSG00000105568 ENSG00000131023 ENSG00000071564 ENSG00000026508 ENSG00000135503 ENSG00000168646 ENSG00000204217 ENSG00000133818 PMC2933269__F1 Activin signaling regulates transcription of the FSHB gene PMC7679954__F1 Signaling pathway of NOD1/2 and most TLRs are interconnected through complex pathways ENSG00000167207 ENSG00000177606 ENSG00000106100 PMC3057180__F2 Exploiting synthetic lethal interactions for the treatment of human cancer ENSG00000149311 ENSG00000175054 ENSG00000159224 PMC2798273__F1 Role of CobT in the late steps of AdoCbl biosynthesis ENSG00000142192 ENSG00000124479 PMC5527962__F4 Cell adhesion pathway and ECM–receptor interaction pathways are affected by RCT ENSG00000149564 ENSG00000292348 ENSG00000136457 ENSG00000135218 ENSG00000168743 ENSG00000026508 ENSG00000154721 PMC4334071__F2 Insulin signaling in ovarian thecal cells and proposed mechanisms for selective insulin resistance ENSG00000169291 ENSG00000198793 PMC5527962__F5 Leukocyte transendothelial migration pathway is affected by RCT ENSG00000292348 ENSG00000169896 ENSG00000166086 ENSG00000154721 ENSG00000162692 ENSG00000115232 ENSG00000135605 ENSG00000121966 ENSG00000154096 PMC1869627__F2 Pathway diagram developed using the Ingenuity Pathways Analysis and Knowledge Base in which all genes changed by more than 1.5 fold were queried ENSG00000197956 ENSG00000143546 ENSG00000041982 ENSG00000131095 ENSG00000155657 PMC3060494__F6 RPA/9-1-1- and hMSH2-mediated ATR activation in DNA damage signaling ENSG00000175054 ENSG00000164053 ENSG00000095002 PMC5880504__F8 Proposed pathway regulating cultured primary mouse hepatocyte levels of ECs: impact of phytocannabinoids (Δ9-THC), 2-AG, and Fabp1 gene ablation ENSG00000117480 ENSG00000163631 PMC4728196__F1 PI3K pathway with respective PI3K inhibitors ENSG00000002330 ENSG00000198793 PMC6831867__F1 Reactive oxygen species (ROS) metabolism ENSG00000137857 ENSG00000140279 ENSG00000086991 ENSG00000074771 PMC6831867__F2 Metabolic interplay between various ROS generators ENSG00000086991 PMC4264123__F1 Hypothetical diagram of LPS-triggered inflammation and apoptosis pathways summarized in A ENSG00000183735 ENSG00000170458 ENSG00000172936 ENSG00000131323 ENSG00000168040 ENSG00000175104 ENSG00000276561 PMC5220130__F7 Schematic representation of the BCR signaling pathway demonstrating the ibrutinib sensitivity of BTK C481 variants and their impact on downstream signaling ENSG00000291971 ENSG00000186716 ENSG00000197943 PMC3714559__F1 Model for resolving transcription-blocking lesions ENSG00000163945 ENSG00000136936 PMC6549003__F6 Proposed model for an auto-regulatory feedback loop between the miR-17-92 cluster and the Wnt/Beta-catenin/LEF1 signaling pathway ENSG00000138795 ENSG00000134982 ENSG00000174804 ENSG00000168036 PMC3310826__F16 Schematic showing alterations to the TAG biosynthesis pathway in AS11 when DGAT1 activity is absent ENSG00000087253 ENSG00000173599 ENSG00000285482 ENSG00000198670 PMC9340544__F5 Heme Biosynthetic Gene Expression Analysis With dPCR in Erythropoietic Protoporphyria Patients ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000158578 ENSG00000256269 ENSG00000188690 PMC8452481__F3 The nervous system in pancreatic cancer ENSG00000143799 ENSG00000137673 ENSG00000100906 ENSG00000291971 ENSG00000198793 ENSG00000170558 ENSG00000047936 ENSG00000153317 ENSG00000168610 ENSG00000087460 ENSG00000136826 ENSG00000064300 ENSG00000061938 ENSG00000136997 ENSG00000167325 ENSG00000171848 ENSG00000026508 ENSG00000100985 ENSG00000139687 ENSG00000146648 PMC3194983__F1 Inhibition of the type I interferon (IFN) induction and signaling pathways by viral proteins of KSHV ENSG00000183735 ENSG00000105397 ENSG00000115415 ENSG00000157601 ENSG00000136869 ENSG00000174611 ENSG00000164342 ENSG00000142166 PMC3712028__F7 Model for the mechanism of regulation of glucose metabolism in muscle and liver by leptin in the VMH ENSG00000198576 ENSG00000115138 ENSG00000168610 PMC11593954__F5 Comparison of neuro-regeneration mechanisms in the peripheral and central nervous systems ENSG00000242689 ENSG00000170558 ENSG00000198793 ENSG00000163914 ENSG00000168036 ENSG00000164690 PMC11661762__F2 Key enzymes of glucose metabolism (gluconeogenesis, green arrows), DNL (blue arrows), and FAO (orange arrows) are activated by TH (in red) ENSG00000169710 ENSG00000175567 PMC4544784__F5 MicroRNA-124 Targets Tip110 Expression and Regulates Hematopoiesis ENSG00000177455 ENSG00000135218 ENSG00000170458 ENSG00000272398 ENSG00000105656 ENSG00000026508 ENSG00000010278 ENSG00000187266 ENSG00000174059 PMC3906548__F1 AT2R-mediated molecular pathways involved in tissue injury ENSG00000026103 PMC3771549__F1 Role of Nox-derived ROS in Ang II-mediated effects in vascular cells PMC10138623__F6 TLR4–RAGE crosstalk participates in the HG-enhanced LPS-induced inflammation in BAMs (created with BioRender ENSG00000143546 ENSG00000189403 ENSG00000172936 ENSG00000136869 PMC6562791__F1 Interconnected pathways of non-essential amino acids (NEAA) metabolism ENSG00000284320 ENSG00000092621 ENSG00000060982 ENSG00000171759 ENSG00000135069 ENSG00000100033 ENSG00000146733 ENSG00000070669 ENSG00000115419 PMC8964769__F6 Publisher Correction: Angiopathic activity of LRG1 is induced by the IL-6/STAT3 pathway ENSG00000170365 ENSG00000091879 ENSG00000168610 PMC9248037__F3 Dependence between estrogen sulfotransferase (SULT1E1) and nuclear transcription factor Nrf-2 regulations via oxidative stress in breast cancer PMC9098828__F1 Updated Understanding of the Crosstalk Between Glucose/Insulin and Cholesterol Metabolism ENSG00000130164 ENSG00000113161 ENSG00000169174 PMC4161047__F1 Pathways implicated in type I IFN production following L ENSG00000164430 ENSG00000088888 ENSG00000167207 ENSG00000106100 PMC2267731__F2 BL module: A network visualization of the top 25 scoring genes in BL PMC4617137__F1 Anabolic pathway of renal sulfatides ENSG00000103089 ENSG00000118402 ENSG00000119915 ENSG00000102172 ENSG00000143418 ENSG00000139624 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000170522 ENSG00000066322 ENSG00000197977 ENSG00000148154 PMC8733402__F1 Longevity Factor FOXO3: A Key Regulator in Aging-Related Vascular Diseases ENSG00000171105 ENSG00000198793 PMC7568723__F6 Histone H2B ubiquitin ligase RNF40 is required for HER2-driven mammary tumorigenesis ENSG00000070087 ENSG00000134215 ENSG00000163914 ENSG00000067900 ENSG00000182541 PMC9167587__F6 Proposed pathway of quercetin in preventing CKD PMC9678516__F9 Exploring the mechanism of Tengli Kangliu Decoction in the prevention and treatment of colorectal cancer precancerous based on network pharmacology ENSG00000171791 ENSG00000145386 ENSG00000196396 ENSG00000104368 ENSG00000183765 ENSG00000180210 ENSG00000117525 ENSG00000082175 ENSG00000163914 ENSG00000136997 ENSG00000166501 ENSG00000123374 ENSG00000282899 ENSG00000263238 ENSG00000104365 ENSG00000173039 ENSG00000173083 ENSG00000007908 ENSG00000213341 ENSG00000125347 ENSG00000132693 ENSG00000007171 ENSG00000132170 ENSG00000108691 ENSG00000177606 ENSG00000151617 ENSG00000005381 ENSG00000146648 ENSG00000159399 PMC8021797__F2 Schematic presentation of the STAT1 signaling pathway ENSG00000159128 ENSG00000105397 ENSG00000115415 ENSG00000027697 ENSG00000168610 ENSG00000142166 PMC6571146__F8 Model depicting the potential involvement of the Mek/ERK1/2-MAPK and the PI3K/Akt/mTOR signaling pathways at different stages of developmental myelination and during adulthood ENSG00000198793 PMC8347825__F2 Targeting DNA Damage Response and Repair to Enhance Therapeutic Index in Cisplatin-Based Cancer Treatment ENSG00000012061 ENSG00000012048 ENSG00000095002 ENSG00000122512 PMC8542838__F3 An Integrated View of Deubiquitinating Enzymes Involved in Type I Interferon Signaling, Host Defense and Antiviral Activities ENSG00000124422 ENSG00000164164 ENSG00000164663 ENSG00000169914 ENSG00000136014 ENSG00000276561 ENSG00000184979 ENSG00000183735 ENSG00000136878 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000083799 ENSG00000277276 PMC6787451__F6 Effects of ASA in SK‐N‐SH (N) cells ENSG00000135446 ENSG00000123374 PMC3392816__F5 Model for inhibitory effect of extracellular nicotinamide phosphoribosyltransferase on insulin-like growth factor-1 function in chondrocytes ENSG00000169047 ENSG00000140443 PMC8380002__F6 Glucose metabolic crosstalk and regulation in brain function and diseases ENSG00000154342 ENSG00000281324 PMC7072213__F2 Biogenesis mechanism of (a) exosomes and (b) MV, and their release processes which are coordinated through two different intracellular pathways, such as exosomes generation pathway and lysosomal degradation pathway ENSG00000041353 ENSG00000137575 ENSG00000111737 PMC8532910__F1 Preclinical Evidence for the Interplay between Oxidative Stress and RIP1-Dependent Cell Death in Neurodegeneration: State of the Art and Possible Therapeutic Implications ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000026103 PMC8558079__F7 Signal Transduction and Molecular Regulation in Fatty Liver Disease ENSG00000126016 ENSG00000186575 ENSG00000144560 ENSG00000114978 ENSG00000131023 PMC9684170__F3 Hypersensitivity reactions to small molecule drugs ENSG00000039537 ENSG00000183695 ENSG00000113600 ENSG00000288512 ENSG00000166278 ENSG00000168610 ENSG00000182326 ENSG00000062485 ENSG00000236625 PMC7352703__F4 Enrichment Kyoto Encyclopaedia of Genes and Genomes (KEGG) analysis of DEGs engaged in the Notch signaling pathway ENSG00000005339 ENSG00000224470 ENSG00000273529 ENSG00000133961 ENSG00000114315 PMC9498168__F6A MiR-942-3p as a Potential Prognostic Marker of Gastric Cancer Associated with AR and MAPK/ERK Signaling Pathway ENSG00000134460 ENSG00000163618 ENSG00000134757 ENSG00000127528 ENSG00000166509 ENSG00000180251 ENSG00000178690 ENSG00000162999 ENSG00000105668 ENSG00000104177 ENSG00000213973 ENSG00000137558 ENSG00000136541 ENSG00000172167 ENSG00000139055 ENSG00000069431 ENSG00000112425 ENSG00000204899 ENSG00000145879 ENSG00000152208 ENSG00000058668 ENSG00000256162 ENSG00000152592 ENSG00000174197 ENSG00000150054 ENSG00000164440 ENSG00000120251 ENSG00000143603 ENSG00000100625 ENSG00000147536 ENSG00000164841 ENSG00000163873 ENSG00000274137 ENSG00000121871 ENSG00000165891 ENSG00000092853 ENSG00000117152 ENSG00000188158 ENSG00000172005 ENSG00000182253 ENSG00000119508 ENSG00000104332 ENSG00000292210 ENSG00000156299 ENSG00000174136 ENSG00000112578 ENSG00000138075 ENSG00000170426 ENSG00000115008 ENSG00000124766 ENSG00000159588 ENSG00000036828 ENSG00000175097 ENSG00000110693 ENSG00000185231 ENSG00000154678 ENSG00000080839 PMC3856587__F2 Genetic pathway predicted to regulate the interaction between 5-HT synthesis, transport and degradation and the stress response mediated by the HPA axis PMC10935043__F7 Diagram picturing two alternative pathways of sorting damaged mitochondrial components into mitochondrial-derived vesicles ENSG00000130340 ENSG00000158828 PMC4474670__F3 Asian Citrus Psyllid Expression Profiles Suggest Candidatus Liberibacter Asiaticus-Mediated Alteration of Adult Nutrition and Metabolism, and of Nymphal Development and Immunity ENSG00000131475 ENSG00000176108 ENSG00000115561 ENSG00000013016 ENSG00000130164 ENSG00000070831 ENSG00000136100 ENSG00000138798 ENSG00000165527 ENSG00000024422 PMC3856587__F3 Simplified model of the regulatory interactions between the serotonin and stress response pathways mediated by the HPA axis ENSG00000165646 PMC3087601__F1 Cellular and bacterial profiles associated with oral epithelium-microbiota interactions ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000094804 ENSG00000132646 ENSG00000123374 ENSG00000277273 ENSG00000276876 ENSG00000093009 PMC8855827__F5 Integrative OMICS Data-Driven Procedure Using a Derivatized Meta-Analysis Approach ENSG00000019991 ENSG00000138378 ENSG00000144802 ENSG00000178078 ENSG00000173757 ENSG00000168610 ENSG00000146648 ENSG00000102468 ENSG00000101213 PMC4474670__F6 Asian Citrus Psyllid Expression Profiles Suggest Candidatus Liberibacter Asiaticus-Mediated Alteration of Adult Nutrition and Metabolism, and of Nymphal Development and Immunity ENSG00000169220 ENSG00000213658 ENSG00000163914 ENSG00000185591 ENSG00000084774 PMC4474670__F7 Asian Citrus Psyllid Expression Profiles Suggest Candidatus Liberibacter Asiaticus-Mediated Alteration of Adult Nutrition and Metabolism, and of Nymphal Development and Immunity ENSG00000170860 ENSG00000135473 ENSG00000152520 ENSG00000083520 ENSG00000179151 ENSG00000114127 ENSG00000088038 ENSG00000111596 ENSG00000236826 ENSG00000080802 ENSG00000130520 ENSG00000087250 ENSG00000166938 PMC5994424__F8 ADM Scaffolds Generate a Pro-regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1 ENSG00000138798 ENSG00000148926 ENSG00000149357 ENSG00000113520 ENSG00000118520 ENSG00000112715 PMC7510352__F1 Families of PDGF/PDGFR and the downstream signalling pathways ENSG00000145431 ENSG00000170365 ENSG00000087245 ENSG00000002330 ENSG00000170962 ENSG00000136997 ENSG00000112715 ENSG00000168610 PMC4488003__F6 The Effects of Methylene Blue on Autophagy and Apoptosis in MRI-Defined Normal Tissue, Ischemic Penumbra and Ischemic Core ENSG00000198793 ENSG00000198125 PMC8651070__F2 Mechanisms Regulating HLA Class-I Antigen Processing Machinery Component Expression in Cancer Cells ENSG00000183735 ENSG00000188554 ENSG00000164430 ENSG00000115415 ENSG00000082512 ENSG00000131323 ENSG00000125347 ENSG00000127191 ENSG00000276561 PMC5983187__F4 Intracellular signaling pathways arising from B common (Bc) receptor activation ENSG00000004455 PMC10796104__F1 Mechanisms of Janus Kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) in chronic pain ENSG00000108691 ENSG00000137033 ENSG00000168610 PMC8684694__F7 Glaucocalyxin A suppresses multiple myeloma progression in vitro and in vivo through inhibiting the activation of STAT3 signaling pathway ENSG00000168610 PMC7649190__F2 Hypothesis that vascular endothelial growth factor (VEGF) may promote T cell exhaustion and therefore Demodex proliferation, by analogy with what happens with tumors ENSG00000089692 ENSG00000145777 PMC7202399__F2 FOXO1 protein activation ENSG00000211445 ENSG00000150907 ENSG00000086991 PMC8122057__F4 Interleukin (IL)-4 signaling sources (A) and targets (B) ENSG00000107485 PMC3797768__F4 An Integrated Approach Based on Multiplexed Protein Array and iTRAQ Labeling for In-Depth Identification of Pathways Associated to IVF Outcome ENSG00000113905 ENSG00000105697 ENSG00000113520 ENSG00000122194 ENSG00000171560 ENSG00000132693 ENSG00000165471 PMC7865468__F1 TGFB in Cancer: Metabolic Driver of the Tolerogenic Crosstalk in the Tumor Microenvironment ENSG00000198793 ENSG00000140284 PMC2880454__F1 Targeting the cancer kinome through polypharmacology ENSG00000171105 ENSG00000146648 PMC6219450__F3 DSB-free recombination-dependent replication.A ENSG00000138346 ENSG00000165392 ENSG00000051180 ENSG00000139618 PMC8979166__F2 Why Does Piscirickettsia salmonis Break the Immunological Paradigm in Farmed Salmon? Biological Context to Understand the Relative Control of Piscirickettsiosis ENSG00000163464 ENSG00000138378 ENSG00000113600 ENSG00000091972 ENSG00000134982 ENSG00000104894 PMC9315303__F7 Genistein promotes M1 macrophage apoptosis and reduces inflammatory response by disrupting miR-21/TIPE2 pathway ENSG00000172936 ENSG00000136869 ENSG00000062716 PMC5408670__F1 Tumor necrosis factorA (TNF)/TNF receptor (TNFR)-mediated cell signaling ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC1502453__F5 Hoxc8-regulated transcriptional network in vivo ENSG00000170365 ENSG00000137834 ENSG00000037965 ENSG00000140937 ENSG00000138798 ENSG00000026508 ENSG00000168036 ENSG00000146648 PMC9031059__F3 Substrates of the MAPK Slt2: Shaping Yeast Cell Integrity ENSG00000260314 ENSG00000100083 ENSG00000117906 ENSG00000108510 ENSG00000166886 PMC11846535__F4 Diagrammatic summary of therapeutic strategies and agents (light purple) targeting the TGFB signaling pathway PMC10443056__F1 Different interventions enhance nerve regeneration for the treatment of AD ENSG00000178860 ENSG00000087085 PMC2649302__F2 Wnt/-catenin signaling pathway ENSG00000281324 ENSG00000134982 ENSG00000168036 PMC2649302__F3 Conversations between Wnt/Beta-catenin and MAPK signaling pathways ENSG00000281324 ENSG00000070831 ENSG00000134982 ENSG00000168036 PMC3586749__F4 Epithelial to Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma ENSG00000138798 ENSG00000100985 ENSG00000146648 ENSG00000046604 PMC2809778__F2 Mitochondrial quality control: insights on how Parkinson’s disease related genes PINK1, Parkin, and Omi/HtrA2 interact to maintain mitochondrial homeostasis ENSG00000158828 ENSG00000115317 PMC9454636__F1 Drosophila as a Model for Human Viral Neuroinfections ENSG00000102871 ENSG00000189056 ENSG00000168040 ENSG00000127191 ENSG00000276561 ENSG00000183735 ENSG00000164430 ENSG00000134070 ENSG00000157625 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC11846535__F1 This figure illustrates Canonical (SMAD dependent) and Non-canonical (SMAD independent) TGFB signaling pathways ENSG00000198793 ENSG00000163914 PMC9454636__F2 Drosophila as a Model for Human Viral Neuroinfections ENSG00000276561 ENSG00000123908 PMC11846535__F2 Exploring TGFB Signaling in Cancer Progression: Prospects and Therapeutic Strategies ENSG00000019991 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000128602 PMC6707713__F4 Interplay between DNA tumor viruses and the host DNA damage response ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000163961 PMC8136133__F11 Prognostic and clinicopathological insights of phosphodiesterase 9A gene as novel biomarker in human colorectal cancer ENSG00000175206 ENSG00000128655 ENSG00000152402 ENSG00000159899 ENSG00000048545 ENSG00000010310 ENSG00000087460 ENSG00000132518 ENSG00000007171 ENSG00000171121 ENSG00000138735 ENSG00000112599 ENSG00000135643 ENSG00000138472 ENSG00000185527 ENSG00000134640 ENSG00000101890 ENSG00000062485 PMC3924201__F4 Two mechanisms for growth-factor-mediated regulation of the Hippo pathway: activation of Ras-MAPK signaling and activation of PI3K-PDK1 signaling ENSG00000129474 ENSG00000138798 ENSG00000198670 PMC3924201__F1 Control of the core Hippo signaling pathway through interacting upstream modules ENSG00000126016 ENSG00000186575 ENSG00000109321 ENSG00000150457 ENSG00000132849 ENSG00000131023 ENSG00000142279 PMC3924201__F2 Hippo pathway-mediated regulation of cell lineage and pluripotency by adhesion and epithelial polarization in the early mouse embryo ENSG00000165556 ENSG00000126016 ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC6481737__F9 Working model of stiffness-dependent calcium response for neutrophils on HUVECs ENSG00000291971 ENSG00000026508 PMC9450835__F10 Summary illustration of the phosphoinositide-initiated membrane tethering and lipid transport (PITT) pathway for rapid lysosomal repair ENSG00000155252 ENSG00000110048 ENSG00000101558 PMC7449905__F4 PAK1 is a key molecular determinant in major cell proliferation pathways ENSG00000138795 ENSG00000149269 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000136997 ENSG00000168036 ENSG00000146648 PMC7449905__F7 PAK1 in autophagy pathways ENSG00000177169 ENSG00000123395 ENSG00000149269 ENSG00000198793 ENSG00000284099 ENSG00000145782 ENSG00000057663 PMC7449905__F9 Crosstalk between PAK1 and other cancer-related pathways ENSG00000149269 ENSG00000198793 ENSG00000197905 ENSG00000007866 ENSG00000074219 PMC6616108__F1 Processing of CD8 ppCT T-cell epitopes ENSG00000232326 ENSG00000273686 PMC8356873__F1 Correlation of alterations in the KEAP1/CUL3/NFE2L2 pathway with radiation failure in larynx squamous cell carcinoma ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC10310781__F1 Amyloid Beta-based therapy for Alzheimer’s disease: challenges, successes and future ENSG00000142192 ENSG00000182240 PMC3858858__F4 Overall PI3K and MAPK-Erk signaling is complex, but can highly influence the balance between cell survival and death ENSG00000002330 ENSG00000198793 PMC3690105__F1 Metabolic pathway of clopidogrel ENSG00000165841 ENSG00000197408 PMC8989865__F7 TGFB activates NLRP3 inflammasome by an autocrine production of TGFB in LX-2 human hepatic stellate cells ENSG00000162711 ENSG00000150782 ENSG00000086991 PMC3837249__F1 Toll-like receptor signaling in liver cells ENSG00000174125 ENSG00000239732 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC11012292__F1 Epigenetics, Nutrition, and the Brain: Improving Mental Health through Diet ENSG00000087085 ENSG00000133027 PMC2678983__F4 IFN-gamma signaling pathway ENSG00000213928 ENSG00000115415 ENSG00000158169 PMC10383978__F3 Differential Inhibition of Anaplerotic Pyruvate Carboxylation and Glutaminolysis-Fueled Anabolism Underlies Distinct Toxicity of Selenium Agents in Human Lung Cancer ENSG00000065833 ENSG00000173599 ENSG00000082212 PMC7168569__F1 Regulatory roles and underlying mechanisms of ELA-APJ axis in heart failure ENSG00000105329 ENSG00000285109 ENSG00000100985 PMC4568774__F1 Anti-tumor mechanism of combi-targeting molecule ENSG00000012061 ENSG00000002330 ENSG00000163235 ENSG00000138798 ENSG00000146648 PMC7990776__F2 BRD4 in innate immunity ENSG00000174125 ENSG00000278718 ENSG00000162711 ENSG00000104365 ENSG00000100906 ENSG00000137757 ENSG00000196954 ENSG00000269335 ENSG00000173039 ENSG00000213341 ENSG00000136807 ENSG00000150782 ENSG00000141867 ENSG00000183735 ENSG00000164430 ENSG00000125538 ENSG00000189403 ENSG00000172936 ENSG00000164342 PMC4875828__F1 Mechanobiology of TGFB Signaling in the Skeleton ENSG00000170365 ENSG00000125398 PMC5260935__F7 Late-phase synthesis of IKBA insulates the TLR4-activated canonical NFKB pathway from noncanonical NFKB signaling in macrophages ENSG00000100906 ENSG00000173039 ENSG00000136869 PMC8584326__F1 Cross-Tolerance and Autoimmunity as Missing Links in Abiotic and Biotic Stress Responses in Plants: A Perspective toward Secondary Metabolic Engineering ENSG00000110934 PMC9370360__F4 Receptor for Advanced Glycation End Products (RAGE): A Pivotal Hub in Immune Diseases ENSG00000142192 ENSG00000144895 PMC6533689__F2 Telomerase regulation and telomere elongation pathway ENSG00000101751 ENSG00000164362 ENSG00000291791 ENSG00000168610 PMC3882437__F4 Perturbed pattern of genes in the peroxisome proliferation activator receptor (PPAR) signaling pathway by DEX administration (ethanol plus DEX vs ENSG00000157184 ENSG00000065833 ENSG00000150991 PMC4055569__F8 Augmenting Microarray Data with Literature-Based Knowledge to Enhance Gene Regulatory Network Inference ENSG00000149311 ENSG00000113328 ENSG00000100290 ENSG00000078900 ENSG00000138798 ENSG00000132646 ENSG00000198793 ENSG00000177606 ENSG00000169710 ENSG00000053254 ENSG00000123374 ENSG00000168610 PMC6906806__F10 The summary of the signaling pathway of TRPC3 upregulation in fibroblasts involved in fibrosis ENSG00000138741 PMC10843903__F6 Increased IGFBP2 in trophoblast cell proliferation and recurrent spontaneous abortion development: A pilot study ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 PMC10525672__F3 Stress Urinary Incontinence: An Unsolved Clinical Challenge PMC8533529__F2 Nicotinamide N-Methyltransferase: An Emerging Protagonist in Cancer Macro(r)evolution ENSG00000105835 PMC7698658__F5 Development of a Peptide Derived from Platelet-Derived Growth Factor (PDGF-BB) into a Potential Drug Candidate for the Treatment of Wounds ENSG00000117724 ENSG00000138778 ENSG00000151657 ENSG00000156970 ENSG00000109321 ENSG00000089685 ENSG00000178999 ENSG00000127191 ENSG00000092820 ENSG00000093009 PMC3942883__F1 Induction and clearance strategies ENSG00000167074 ENSG00000198125 PMC9066095__F3 New insights into checkpoint inhibitor immunotherapy and its combined therapies in hepatocellular carcinoma: from mechanisms to clinical trials ENSG00000154342 ENSG00000168036 PMC4591923__F1 Peptide vaccines and peptidomimetics targeting HER and VEGF proteins may offer a potentially new paradigm in cancer immunotherapy ENSG00000163235 ENSG00000198793 ENSG00000128052 ENSG00000112715 ENSG00000146648 PMC4231819__F1 Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential ENSG00000170458 ENSG00000125538 ENSG00000172936 ENSG00000175104 PMC6928879__F1 AHR-dependent signaling pathways ENSG00000146648 ENSG00000106546 PMC6299603__F2 Adipocytokines mediate pancreatic cancer tumorigenesis by different signaling mechanisms ENSG00000135547 ENSG00000198793 ENSG00000096717 ENSG00000168610 PMC10957538__F1 Impact of particulate air pollution on airway injury and epithelial plasticity; underlying mechanisms ENSG00000162711 ENSG00000125538 ENSG00000117983 PMC6299603__F3 Altered gut microbiota is responsible for pancreatic cancer progression ENSG00000170458 ENSG00000198793 ENSG00000172936 PMC9290708__F1 Review article: therapeutic aspects of bile acid signalling in the gut‐liver axis ENSG00000111012 ENSG00000160867 ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC5359376__F5 Enrichment analysis for pathway map ontologies revealed significant biological processes associated with the most promising targets commonly deregulated in mouse and human ALS ENSG00000138798 ENSG00000105656 PMC6700737__F1 MiR-126-orchestrated regulation of pDC effector functions in lymph nodes undergoing an immune response ENSG00000239732 ENSG00000198793 ENSG00000172936 ENSG00000276561 PMC9290708__F3 Review article: therapeutic aspects of bile acid signalling in the gut‐liver axis ENSG00000160867 ENSG00000167910 PMC7963413__F2 Cascade of events triggered by the overexpression of RB1CC1 in SCZ pathogenesis ENSG00000023287 PMC12086142__F1 Regulatory mechanisms of NLRP3 inflammasome in PF ENSG00000278718 ENSG00000162711 ENSG00000105329 ENSG00000158828 ENSG00000172936 PMC2990064__F4 Modeling Dose-response at Low Dose: A Systems Biology Approach for Ionization Radiation ENSG00000171791 PMC4322985__F1 BRAF vs RAS oncogenes: are mutations of the same pathway equal? differential signalling and therapeutic implications ENSG00000138798 ENSG00000146648 PMC2891968__F5 Cellular pathways leading to upregulation of COX-2 in neutrophils ENSG00000170458 ENSG00000136869 PMC4850258__F5 Regulatory interactions of Usv101 ENSG00000138433 ENSG00000177464 ENSG00000185591 PMC2093951__F9 NOVEL VIP SIGNALING PATHWAY IN T CELLS cAMP→ Protein Tyrosine Phosphatase (SHP-2?)→JAK2/STAT4→Th1 differentiation ENSG00000096996 ENSG00000105397 ENSG00000146469 PMC6297758__F7 Involvement of c-myb and E2F1 in the expression and amplification of MYCN ENSG00000185513 ENSG00000112312 PMC6342007__F2 Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases ENSG00000183735 ENSG00000123240 ENSG00000137275 ENSG00000102871 ENSG00000157625 ENSG00000083799 ENSG00000168040 ENSG00000285379 PMC10957538__F2 Epithelial plasticity and impact of particulate matter (PM): Exposure to PM in short term, leads to inhibition of Notch1 by stimulating STAT3 and aryl hydrocarbon receptor (AhR) activation in basal epithelial cells ENSG00000141867 ENSG00000169554 ENSG00000151835 ENSG00000170558 ENSG00000168610 ENSG00000106546 PMC10957538__F3 Impact of particulate matter (PM) on airway remodelling ENSG00000163739 ENSG00000169429 ENSG00000113525 PMC8386127__F11 TREM2, Driving the Microglial Polarization, Has a TLR4 Sensitivity Profile After Subarachnoid Hemorrhage ENSG00000167601 ENSG00000112977 ENSG00000172936 ENSG00000136869 ENSG00000137845 PMC3728834__F7 Proposed model illustrating the effects of reduced TH in thyroid cancer development in ThrbPV/PV-PTU mice PMC6478618__F2 Nonalcoholic fatty liver disease-Kyoto Encyclopedia of Genes and Genomes pathway and mechanisms of disease pathogenesis ENSG00000171105 ENSG00000128272 ENSG00000078747 ENSG00000169047 ENSG00000100219 ENSG00000059145 ENSG00000127191 PMC5713364__F7 Analysis of the interconnection between AKAP12 and the merged networks of related joint diseases and functions ENSG00000102032 ENSG00000087116 PMC6602343__F1 Developmental signaling pathway architectures sense, process and control ligands in space and time ENSG00000138798 ENSG00000168036 ENSG00000128602 PMC5039030__F8 Model - DPP9 is a negative regulator for Syk signalling, targeting active Syk for degradation by the N-end rule pathway ENSG00000110395 ENSG00000186716 ENSG00000142002 PMC4797178__F5 GeneGO pathway map “Development_TGF-beta-dependent induction of EMT via SMADs” is significantly enriched for genes differentially expressed between MCF-7-Snail and MCF-7-Control cells ENSG00000019991 ENSG00000170558 ENSG00000185591 PMC2978223__F1 Daphnia pulex insulin and TOR signalling pathways, adapted from Drosophila melanogaster PMC4905267__F1 Common vesicular trafficking module in the assembly of the immune synapse and the primary cilium ENSG00000109083 ENSG00000134982 ENSG00000128602 PMC11204038__F1 Schematic diagram showing the NAD+ metabolic pathway ENSG00000077009 ENSG00000105835 ENSG00000130649 ENSG00000096717 ENSG00000106733 PMC4117641__F5 TRiC/CCT Chaperone Is Implicated in Alzheimer's Disease Based on Patient GWAS and an RNAi Screen in ABeta-Expressing Caenorhabditis elegans ENSG00000120438 ENSG00000115540 PMC11850097__F11 Action of ZIP8 in macrophage polarisation and IDD ENSG00000154736 ENSG00000163235 PMC7226805__F1 Molecular mechanisms regulating autophagy ENSG00000177169 ENSG00000123395 ENSG00000126775 ENSG00000104142 ENSG00000145782 PMC4874035__F7 Vascular control of the haematopoietic microenvironment by Slit/Robo signalling ENSG00000070831 PMC11241496__F2 Targeted therapies in RAS-RAF-MAPK pathway ENSG00000198793 ENSG00000146648 PMC11241496__F3 Targeted therapies in the vascular endothelial growth factor (VEGF) pathway ENSG00000167601 ENSG00000198793 ENSG00000112715 ENSG00000150630 PMC5962337__F7 Neurotoxicity Linked to Dysfunctional Metal Ion Homeostasis and Xenobiotic Metal Exposure: Redox Signaling and Oxidative Stress ENSG00000188786 ENSG00000214435 ENSG00000103569 ENSG00000165269 PMC5713364__F6 Network analysis by Ingenuity®Pathway Analysis (IPA) indicated molecules associated with rheumatic disease and inflammation of joint ENSG00000143248 ENSG00000149212 ENSG00000112078 ENSG00000063660 ENSG00000146592 ENSG00000100739 ENSG00000164344 ENSG00000122194 ENSG00000151388 ENSG00000132170 PMC5512440__F7 Hepatocyte ABCA1 deletion impairs liver insulin signaling and lipogenesis ENSG00000135218 ENSG00000130164 PMC3575813__F10 Presence of a diversity of Alu-mediated events in genes involved in apoptosis ENSG00000149311 ENSG00000002330 ENSG00000102871 ENSG00000172936 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC7933466__F1 Metabolites regulating nucleic acid sensing pathways ENSG00000183735 ENSG00000088888 ENSG00000198829 ENSG00000164342 ENSG00000079999 PMC7819868__F1 REG4 signaling pathway ENSG00000165556 ENSG00000134193 ENSG00000170775 ENSG00000163235 ENSG00000135446 ENSG00000168036 ENSG00000185591 ENSG00000105810 ENSG00000146648 PMC8079368__F4 Molecular mechanism of lateral bud differentiation of Pinus massoniana based on high-throughput sequencing ENSG00000110934 PMC4915362__F3 Converging roles of caspases in inflammasome activation, cell death and innate immunity ENSG00000162711 ENSG00000167207 ENSG00000187796 ENSG00000137275 ENSG00000125538 ENSG00000172936 ENSG00000168040 ENSG00000285379 ENSG00000026103 PMC9468863__F2 Impact of local anesthetics on epigenetics in cancer ENSG00000198793 ENSG00000124766 ENSG00000146648 PMC4915362__F4 Converging roles of caspases in inflammasome activation, cell death and innate immunity ENSG00000162711 ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000137275 ENSG00000125538 ENSG00000120868 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC10900617__F8 ZnONPs disrupt lysosome activity and impair autophagic flux to facilitate exosome secretion in keratinocytes and macrophages ENSG00000174125 ENSG00000162711 ENSG00000164342 PMC7468567__F4 Target genes and pathways of COL-3 and CGP-60474 in treating lung injury in COVID-19 ENSG00000073803 ENSG00000108691 ENSG00000224320 ENSG00000147168 ENSG00000070831 ENSG00000205302 ENSG00000177606 ENSG00000015285 ENSG00000175097 ENSG00000108518 ENSG00000089159 ENSG00000026103 PMC8430223__F2 Periostin: An Emerging Molecule With a Potential Role in Spinal Degenerative Diseases ENSG00000196411 ENSG00000281324 ENSG00000133110 ENSG00000163599 PMC8996945__F2 Prognostic Role and Significance of Dll4 and Toll-like Receptors in Cancer Development ENSG00000184916 PMC6509750__F3 Influence of TGFB1 on the balance between the canonical WNT/Beta-catenin signaling and PPARG ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8430223__F3 Periostin: An Emerging Molecule With a Potential Role in Spinal Degenerative Diseases ENSG00000128272 ENSG00000133110 ENSG00000144895 PMC8430223__F4 Periostin: An Emerging Molecule With a Potential Role in Spinal Degenerative Diseases ENSG00000133110 ENSG00000149968 ENSG00000198793 ENSG00000168036 ENSG00000007171 ENSG00000158859 PMC8430223__F5 Periostin: An Emerging Molecule With a Potential Role in Spinal Degenerative Diseases ENSG00000162711 ENSG00000133110 ENSG00000125538 PMC5962337__F1 Neurotoxicity Linked to Dysfunctional Metal Ion Homeostasis and Xenobiotic Metal Exposure: Redox Signaling and Oxidative Stress ENSG00000173992 ENSG00000144410 ENSG00000138495 ENSG00000123191 ENSG00000166260 ENSG00000177556 ENSG00000240230 ENSG00000133028 ENSG00000284194 PMC7587925__F3 Kupffer Cells ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC3606533__F1 Genes in choline/1-carbon metabolism and related pathways influence hepatic lipid balance ENSG00000005471 ENSG00000100344 ENSG00000134982 ENSG00000070214 ENSG00000016391 ENSG00000133027 PMC11011430__F5 Signaling pathways upregulated in higher Gleason grade groups ENSG00000118007 ENSG00000164190 ENSG00000058804 ENSG00000113569 ENSG00000125676 ENSG00000129933 ENSG00000140534 ENSG00000093009 ENSG00000172167 ENSG00000123374 ENSG00000205937 ENSG00000071539 ENSG00000213024 ENSG00000138750 ENSG00000108055 ENSG00000095319 ENSG00000169251 ENSG00000126883 ENSG00000150459 ENSG00000155561 ENSG00000196313 ENSG00000131652 ENSG00000145604 ENSG00000162385 ENSG00000163904 ENSG00000101972 ENSG00000164902 ENSG00000132646 ENSG00000172005 ENSG00000164754 ENSG00000163634 ENSG00000125450 ENSG00000069248 ENSG00000132341 PMC11011430__F6 Analysis of the Gene Networks and Pathways Correlated with Tissue Differentiation in Prostate Cancer ENSG00000124102 ENSG00000182533 ENSG00000130528 ENSG00000156026 ENSG00000186716 ENSG00000183691 PMC3262916__F2 Mechanism of action of vitamin D and the vitamin D receptor in colorectal cancer prevention and treatment ENSG00000134982 ENSG00000168036 PMC11204910__F1 Heme biosynthetic pathway in erythroid cells and the role of ATP-binding cassette transporter B7 (ABCB7 gene): The first enzyme of heme synthesis is 5-aminolevulinate synthase (ALAS2), which is the rate-limiting enzyme ENSG00000182511 ENSG00000147454 ENSG00000100209 ENSG00000158578 ENSG00000147123 PMC7923230__F6 New Gene Markers Expressed in Porcine Oviductal Epithelial Cells Cultured Primary In Vitro Are Involved in Ontological Groups Representing Physiological Processes of Porcine Oocytes ENSG00000127990 ENSG00000101670 ENSG00000141161 ENSG00000139610 ENSG00000259207 ENSG00000143320 ENSG00000197632 ENSG00000086991 ENSG00000100170 ENSG00000134363 ENSG00000265972 ENSG00000154096 PMC7923230__F2 ‘Signaling pathways regulating pluripotency of stem cells’ KEGG pathway ENSG00000084093 ENSG00000134982 ENSG00000183691 ENSG00000177606 ENSG00000156574 ENSG00000128342 ENSG00000114315 ENSG00000168610 ENSG00000016082 PMC3984709__F9 Schematic diagram of the proposed interface between mechanostimulation and biological signaling at acupoint ENSG00000110218 ENSG00000196689 PMC9681895__F3 Effect of maternal body mass index on the steroid profile in women with gestational diabetes mellitus PMC9172006__F3 TMEM16A as a potential treatment target for head and neck cancer ENSG00000291971 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC8590447__F12 SARS-CoV-2 deregulates the vascular and immune functions of brain pericytes via Spike protein ENSG00000074181 ENSG00000130234 PMC4721683__F4 Signaling pathways related to the activity of oxaliplatin and 5-FU for colon cancer cell lines ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000105639 ENSG00000146648 ENSG00000196712 PMC2556095__F6 In the canonical TGFB signalling pathway, ligands signal through type I and II transmembrane protein kinase receptors ENSG00000105329 ENSG00000172818 PMC2556095__F4 TGFBeta-related signalling pathway controlling Myc activity in keratinocytes ENSG00000136997 ENSG00000205250 ENSG00000172818 PMC9661392__F8 Effect of transmembrane protein 100 on prostate cancer progression by regulating SCNN1D through the FAK/PI3K/AKT pathway ENSG00000162572 ENSG00000166292 ENSG00000170558 PMC6700476__F1 Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells ENSG00000185155 ENSG00000164458 ENSG00000198793 PMC11074473__F3 M5C methylation in innate immunity (By figdraw ENSG00000174125 ENSG00000037474 ENSG00000276561 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000130234 ENSG00000187554 ENSG00000130305 ENSG00000167468 ENSG00000136869 ENSG00000172936 ENSG00000164342 PMC10813482__F1 DNA modification of MSCs in SONFH ENSG00000178860 ENSG00000157240 PMC4885164__F1 Role of stromal cell-derived factor 1A pathway in bone metastatic prostate cancer ENSG00000178860 ENSG00000161921 ENSG00000135535 ENSG00000121966 PMC6076887__F3 MRN complex activates possible (alternative) pathways at DSBs ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000276618 ENSG00000138346 ENSG00000051180 ENSG00000139618 PMC4967105__F3 SKN-1 in the development of C ENSG00000125686 ENSG00000168036 PMC4652017__F2 Putative stress signaling pathway in wheat where functional genomics contribute ENSG00000105722 PMC4460069__F1 Comparative Transcriptome Analysis Reveals the Influence of Abscisic Acid on the Metabolism of Pigments, Ascorbic Acid and Folic Acid during Strawberry Fruit Ripening ENSG00000228716 ENSG00000173540 ENSG00000110921 ENSG00000095059 ENSG00000105251 ENSG00000197429 ENSG00000137563 PMC5803081__F1 Beyond Alkylating Agents for Gliomas: Quo Vadimus? ENSG00000136997 ENSG00000159399 PMC9270554__F7 Metabolic plasticity in blast crisis-chronic myeloid leukaemia cells under hypoxia reduces the cytotoxic potency of drugs targeting mitochondria ENSG00000131473 ENSG00000065833 ENSG00000112972 ENSG00000169710 ENSG00000105953 PMC6155262__F7 CCL19 suppresses angiogenesis through promoting miR-206 and inhibiting Met/ERK/Elk-1/HIF-1A/VEGF-A pathway in colorectal cancer ENSG00000126353 ENSG00000112715 PMC4122337__F2 Potential roles of GPR120 and its agonists in the management of diabetes ENSG00000162711 ENSG00000125538 PMC9616595__F1 Intersection of metabolism and inflammation is governed by the intracellular topology of hexokinases and the metabolic fate of glucose ENSG00000143546 ENSG00000163220 ENSG00000159399 ENSG00000283100 PMC8151958__F2 GSK-3B in the Regulation of Protein Turnover, Myosin Phenotype, and Oxidative Capacity in Skeletal Muscle under Disuse Conditions ENSG00000168036 PMC9293977__F5 Bone remodeling: an operational process ensuring survival and bone mechanical competence ENSG00000196411 ENSG00000198793 ENSG00000133216 PMC4589110__F4 TrxR1 as a Potent Regulator of the Nrf2-Keap1 Response System ENSG00000285250 ENSG00000265972 ENSG00000105227 PMC5600869__F3 Passive DNA demethylation pathway ENSG00000088305 PMC5600869__F4 Active DNA demethylation pathway ENSG00000088305 ENSG00000123415 ENSG00000139372 ENSG00000129071 PMC11622572__F7 Signaling pathway analysis of genes in cluster 5 using KEGG database (A) Gene expression profile during functional unloading (B) Heatmap of DEGs with p ENSG00000166819 ENSG00000135218 ENSG00000112972 ENSG00000167114 ENSG00000173391 ENSG00000157184 ENSG00000167772 ENSG00000161533 ENSG00000100979 ENSG00000167676 ENSG00000115361 ENSG00000158874 ENSG00000113790 PMC5955127__F3 Brief report: RRx-001 is a c-Myc inhibitor that targets cancer stem cells ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC5343833__F6 Involvement of TGFB/Smad pathway in AA-induced fibrogenesis PMC4197574__F3 Studying ultradian oscillations using optogenetic tools ENSG00000198793 ENSG00000139352 PMC4861305__F1 Decorin induces autophagy in endothelial cells ENSG00000198793 ENSG00000198300 PMC4066640__F5 MYC autorepression and general cellular gene repression by histone modification ENSG00000136997 PMC5009385__F7 Insulin-like growth factor 1 regulates growth of endometrial carcinoma through PI3k signaling pathway ENSG00000197081 ENSG00000140443 PMC7247696__F1 Toll-like-receptor (TLR)-4, after activation by pathogen-associated molecular patterns (PAMPs) and danger-associated molecular patterns (DAMPs) supported by myeloid differentiation factor-2 (MD-2), initiates downstream signaling in two major ways ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC7247696__F2 TLR-4 Signaling vs. Immune Checkpoints, miRNAs Molecules, Cancer Stem Cells, and Wingless-Signaling Interplay in Glioblastoma Multiforme—Future Perspectives ENSG00000183735 ENSG00000050165 PMC7828596__F1 Canonical aryl-hydrocarbon receptor (AhR) pathway ENSG00000110711 ENSG00000106546 PMC5503214__F7 Dgat1 and Dgat2 regulate enterocyte triacylglycerol distribution and alter proteins associated with cytoplasmic lipid droplets in response to dietary fat ENSG00000285482 ENSG00000285199 ENSG00000062282 PMC11806588__F2 The potential pathways and mechanisms of genes associated with skin colour-related phenotypes ENSG00000101440 ENSG00000137265 ENSG00000178773 ENSG00000140995 ENSG00000197912 PMC11806588__F3 The potential pathways and mechanisms of genes associated with wrinkling and sagging-related phenotypes ENSG00000142611 ENSG00000069667 PMC5600869__F1 Schematic diagram for molecular mechanisms of activation of ER stress ENSG00000124102 ENSG00000128272 ENSG00000144895 PMC11806588__F4 The potential pathways and mechanisms of genes associated with skin cancer-related phenotypes ENSG00000164362 ENSG00000274811 PMC9479192__F1 Wnt signaling cascade in the pathogenesis of osteoarthritis and related promising treatment strategies ENSG00000134982 ENSG00000168036 PMC3374844__F1 Three major UPR pathways in metazoans ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC9414803__F4 Portulaca oleracea L. Extract Regulates Hepatic Cholesterol Metabolism via the AMPK/MicroRNA-33/34a Pathway in Rats Fed a High-Cholesterol Diet ENSG00000042832 ENSG00000005421 ENSG00000167910 ENSG00000143921 PMC5470961__F5 Employing an orthotopic model to study the role of epithelial-mesenchymal transition in bladder cancer metastasis ENSG00000087095 ENSG00000171105 ENSG00000095739 ENSG00000136153 ENSG00000171540 ENSG00000121053 PMC9095829__F10 TRP Channels as Molecular Targets to Relieve Endocrine-Related Diseases ENSG00000148926 ENSG00000072315 ENSG00000138741 PMC3362997__F10 Competitive displacement of DMP1 by ASARM peptide modulates PHEX–DMP1-mediated FGF23 expression (see central osteoblast in green) ENSG00000118972 ENSG00000152592 ENSG00000110719 PMC6292929__F1 CBL0137 exhibits its antitumor activity via multiple pathways ENSG00000284774 ENSG00000110395 ENSG00000148400 PMC9214065__F1 Development and clinical advancement of small molecules for ex vivo expansion of hematopoietic stem cell ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000148798 ENSG00000168036 PMC6440987__F2 Pool sizes of intracellular metabolites in S ENSG00000074800 ENSG00000124253 ENSG00000146701 PMC9268386__F2 Estrogen-Related Receptor A: A Significant Regulator and Promising Target in Bone Homeostasis and Bone Metastasis ENSG00000112701 ENSG00000111537 ENSG00000115415 ENSG00000136997 PMC9268386__F3 Estrogen-Related Receptor A: A Significant Regulator and Promising Target in Bone Homeostasis and Bone Metastasis ENSG00000105329 ENSG00000198793 ENSG00000108688 ENSG00000112715 PMC8787094__F1 Shaping the Innate Immune Response Through Post-Transcriptional Regulation of Gene Expression Mediated by RNA-Binding Proteins ENSG00000026297 ENSG00000278718 ENSG00000162711 ENSG00000124256 ENSG00000089127 ENSG00000164430 ENSG00000088888 ENSG00000124201 ENSG00000172936 ENSG00000168404 ENSG00000135828 ENSG00000285379 ENSG00000116747 ENSG00000164342 PMC3230308__F1 Autophagy pathway and relationship to mTOR signaling ENSG00000110497 ENSG00000198382 ENSG00000198793 ENSG00000140464 PMC3473259__F2 Main pathway disorders leading to muscle proteolysis, atrophy, hypoxia and anti-oxidant response ENSG00000261832 ENSG00000161544 ENSG00000110395 ENSG00000108515 ENSG00000150907 ENSG00000198793 ENSG00000132388 ENSG00000166971 ENSG00000072609 ENSG00000152556 PMC2727910__F1 Map of arachidonic acid (AA) cascade ENSG00000226275 PMC9686921__F6 NADPH Oxidase 5 (NOX5) Overexpression Promotes Endothelial Dysfunction via Cell Apoptosis, Migration, and Metabolic Alterations in Human Brain Microvascular Endothelial Cells (hCMEC/D3) ENSG00000120314 ENSG00000108298 ENSG00000124614 ENSG00000109475 ENSG00000162244 ENSG00000136942 ENSG00000108107 ENSG00000083845 PMC6414445__F9 Rickettsia conorii and R ENSG00000125166 ENSG00000131473 ENSG00000130204 ENSG00000138029 ENSG00000100412 ENSG00000285121 ENSG00000078668 ENSG00000146701 ENSG00000082212 ENSG00000131828 ENSG00000091140 ENSG00000062485 PMC9596445__F5 Phenylpropane Metabolic Pathway Illustrates in flavonoids accumulation and lignin synthesis in Populus wilsonii ENSG00000117525 ENSG00000105227 ENSG00000084774 PMC9450349__F5 ASXL1/2 mutations and myeloid malignancies ENSG00000141867 ENSG00000163930 ENSG00000198793 PMC7324642__F2 Humoral innate immune signaling pathways ENSG00000197471 ENSG00000162924 ENSG00000168040 PMC2330230__F9 Candidate interactors and their putative postion in the Frizzled signaling pathway ENSG00000214513 ENSG00000134982 ENSG00000146648 PMC12235022__F6 Investigating the Therapeutic Mechanisms of Honeysuckle (China) in Sepsis Through Network Pharmacology and Experimental Validation ENSG00000163464 ENSG00000167207 ENSG00000105835 ENSG00000134982 ENSG00000148926 ENSG00000170606 ENSG00000160710 ENSG00000138071 ENSG00000171791 ENSG00000124762 ENSG00000177455 ENSG00000041982 ENSG00000116688 ENSG00000160703 ENSG00000115138 ENSG00000277263 ENSG00000164400 ENSG00000157625 ENSG00000136869 ENSG00000062485 ENSG00000092439 ENSG00000154589 ENSG00000204671 ENSG00000146469 ENSG00000108342 ENSG00000110680 ENSG00000145777 ENSG00000132693 ENSG00000132170 ENSG00000118785 ENSG00000170458 ENSG00000291603 ENSG00000163568 ENSG00000114737 ENSG00000122194 ENSG00000144476 ENSG00000142224 ENSG00000124181 ENSG00000171119 ENSG00000117407 ENSG00000125650 ENSG00000026103 ENSG00000132906 ENSG00000244165 ENSG00000285433 ENSG00000086991 ENSG00000129450 ENSG00000174804 ENSG00000275126 ENSG00000178363 ENSG00000165059 ENSG00000277943 ENSG00000019582 ENSG00000177606 ENSG00000134460 ENSG00000090534 ENSG00000110799 ENSG00000163737 ENSG00000171388 ENSG00000095585 ENSG00000239732 ENSG00000136997 ENSG00000139193 ENSG00000152266 ENSG00000112964 ENSG00000007908 ENSG00000091879 ENSG00000157005 ENSG00000124205 ENSG00000007171 ENSG00000291983 ENSG00000260314 ENSG00000226275 ENSG00000026508 ENSG00000136160 ENSG00000151617 ENSG00000112115 ENSG00000115009 ENSG00000051523 ENSG00000107562 ENSG00000002330 ENSG00000138798 ENSG00000130522 ENSG00000198793 ENSG00000143226 ENSG00000121966 ENSG00000010671 ENSG00000179295 ENSG00000150782 ENSG00000128165 ENSG00000105664 ENSG00000109861 ENSG00000149968 ENSG00000284099 ENSG00000113520 ENSG00000171560 ENSG00000164342 ENSG00000081041 ENSG00000140678 ENSG00000188822 ENSG00000005339 ENSG00000169896 ENSG00000172243 ENSG00000173039 ENSG00000198626 ENSG00000168610 ENSG00000079999 ENSG00000108691 ENSG00000111537 ENSG00000120899 ENSG00000141480 ENSG00000164362 ENSG00000171608 PMC12235022__F7 Investigating the Therapeutic Mechanisms of Honeysuckle (China) in Sepsis Through Network Pharmacology and Experimental Validation ENSG00000105397 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000143387 PMC6741895__F7 The FA pathways involved in ABeta-induced neuronal dystrophy ENSG00000142192 ENSG00000110395 ENSG00000010810 PMC5063343__F5 Heat Stress and Lipopolysaccharide Stimulation of Chicken Macrophage-Like Cell Line Activates Expression of Distinct Sets of Genes ENSG00000105993 ENSG00000132906 ENSG00000023287 ENSG00000187522 ENSG00000140403 ENSG00000164305 ENSG00000277943 ENSG00000150782 ENSG00000111537 ENSG00000126803 ENSG00000177606 ENSG00000136869 ENSG00000175104 ENSG00000113302 ENSG00000189067 PMC3234268__F5 Genome Characterization of the Oleaginous Fungus Mortierella alpina ENSG00000131473 ENSG00000197713 ENSG00000197977 ENSG00000153574 ENSG00000120437 ENSG00000128602 ENSG00000168237 ENSG00000102977 PMC5031209__F2 Apical signals inhibit nuclear YAP localisation ENSG00000291971 ENSG00000163914 ENSG00000146648 PMC9553898__F8 Possible scheme depicting the role of mTORC1 signaling in estrogen-induced epithelial cell proliferation and differentiation in mouse vagina ENSG00000124882 ENSG00000141564 PMC5437397__F7 RNA interference (RNAi) pathway members in malacostracans ENSG00000065833 ENSG00000092847 ENSG00000023697 ENSG00000113360 ENSG00000123908 PMC5010773__F1 Representation of Canonical Wnt/Beta-catenin pathway ENSG00000134982 ENSG00000163914 ENSG00000136997 ENSG00000168036 PMC7599158__F3 Proposed molecular functions for lncRNAs PICSAR and PRECSIT in cSCC ENSG00000166670 ENSG00000146648 PMC11617869__F2 SSA significantly impacts cancer by inhibiting cell proliferation, inducing apoptosis, suppressing invasion, reducing cell growth, and alleviating skin toxicity ENSG00000002330 ENSG00000291971 ENSG00000198793 ENSG00000086991 ENSG00000145321 ENSG00000146648 ENSG00000121966 PMC321741__F1 Signaling pathways for TLR-3 and TLR-4 ENSG00000136869 ENSG00000164342 PMC4267955__F10 Loss of signaling via GA13 in germinal center B cell-derived lymphoma ENSG00000120063 ENSG00000076928 ENSG00000182162 ENSG00000267534 PMC4409298__F7 BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses ENSG00000170365 ENSG00000108691 PMC5732027__F5 Pan-arthropod analysis reveals somatic piRNAs as an ancestral defence against transposable elements ENSG00000101751 ENSG00000123908 PMC3680431__F7 Acute-Phase Serum Amyloid A in Osteoarthritis: Regulatory Mechanism and Proinflammatory Properties ENSG00000135218 ENSG00000125538 ENSG00000145321 ENSG00000136869 PMC8073961__F2 Role of adiponectin in VSMC ENSG00000116688 ENSG00000169047 PMC11654178__F4 Upstream Pathway of Triterpenoid Synthesis in C ENSG00000160752 ENSG00000110921 ENSG00000113161 ENSG00000167508 PMC4424351__F9 The role of UV radiation in the modulation of STING-dependent IRF3 activation ENSG00000177169 ENSG00000110497 ENSG00000183735 ENSG00000164430 PMC9676400__F7 Chicken anemia virus VP1 negatively regulates type I interferon via targeting interferon regulatory factor 7 of the DNA-sensing pathway ENSG00000183735 ENSG00000164430 ENSG00000276561 PMC3318683__F12 A model of MMP-9 sorting and trafficking in activated macrophages ENSG00000135404 PMC5574206__F1 BMP signalling utilises canonical Smad dependant pathways and non-canonical Smad-independent pathways ENSG00000123091 ENSG00000069869 ENSG00000095739 ENSG00000198742 PMC8258627__F1 Advances in the role of autophagy in the development of retinoblastoma ENSG00000177169 ENSG00000198793 ENSG00000112561 ENSG00000145782 ENSG00000057663 PMC3798270__F6 The Bacterial Response Regulator ArcA Uses a Diverse Binding Site Architecture to Regulate Carbon Oxidation Globally ENSG00000073578 ENSG00000186063 ENSG00000087085 PMC7408918__F1 Androgen at supraphysiological level (SAL) induces cellular senescence through the PI3K/Src/Akt/mTOR pathway ENSG00000291971 ENSG00000198793 PMC11594236__F1 Cellular mechanisms involved in OA synovitis in osteoarthritis ENSG00000108691 ENSG00000143546 PMC7408918__F2 AR antagonist induces cellular senescence in PCa through the Src/Akt pathway ENSG00000291971 PMC11594236__F2 Cells of innate immunity and network of mediators in OA synovitis ENSG00000170458 ENSG00000115415 ENSG00000115523 ENSG00000090659 PMC3411967__F1 Cell-proliferative signaling pathways in lung tumors ENSG00000138798 ENSG00000146648 PMC6510479__F4 Epigenetic reprogramming of the innate anti-viral interferon response (IFN) ENSG00000173039 ENSG00000172936 ENSG00000125347 PMC3809064__F1 Targeting Mutant Fibroblast Growth Factor Receptors in Cancer ENSG00000115008 ENSG00000110395 ENSG00000115904 PMC11854957__F1 Transcription Factor CcMYB330 Regulates Capsaicinoid Biosynthesis in Pepper Fruits ENSG00000145020 ENSG00000062485 PMC9168780__F12 Emerging roles of cystathionine Beta-synthase in various forms of cancer ENSG00000131473 ENSG00000122691 ENSG00000168036 PMC9192746__F5 Quercetin against atrial fibrillation explored by network pharmacology combined with molecular docking and experimental validation ENSG00000170458 ENSG00000115718 ENSG00000127311 PMC12069211__F9 Construction of “KEGG pathway-target” network ENSG00000086696 ENSG00000198610 ENSG00000087085 ENSG00000162924 ENSG00000148344 ENSG00000118777 ENSG00000007171 ENSG00000158125 ENSG00000187134 ENSG00000185015 ENSG00000198517 ENSG00000198074 ENSG00000136869 ENSG00000105810 ENSG00000100985 ENSG00000275565 ENSG00000113448 ENSG00000167434 PMC4392267__F8 Proposed model for the involvement of TRIP in the TNF-induced inflammatory response ENSG00000102871 ENSG00000125538 ENSG00000127191 PMC7746852__F2 Alteration of host signaling pathways by HIV-1 ENSG00000162711 ENSG00000102871 ENSG00000168040 ENSG00000121966 ENSG00000026103 PMC7746852__F3 Insights into the counteraction of host defense by viral protease and Vpu ENSG00000131779 ENSG00000183735 ENSG00000088888 ENSG00000168036 ENSG00000164751 ENSG00000162928 PMC9168780__F10 Emerging roles of cystathionine Beta-synthase in various forms of cancer ENSG00000198793 ENSG00000110931 PMC9168780__F11 Emerging roles of cystathionine Beta-synthase in various forms of cancer ENSG00000198793 ENSG00000171791 ENSG00000079999 PMC3071576__F2 Proof of Concept Trials in Bipolar Disorder and Major Depressive Disorder: A Translational Perspective in the Search for Improved Treatments ENSG00000196531 PMC7290051__F5 Interaction between imaging agents and the blood-brain barrier ENSG00000163406 ENSG00000197901 ENSG00000144659 ENSG00000135776 ENSG00000066926 ENSG00000126088 ENSG00000256269 ENSG00000115657 ENSG00000118777 ENSG00000163631 PMC8739471__F10 Integrated Pharmacogenetics Analysis of the Three Fangjis Decoctions for Treating Arrhythmias Based on Molecular Network Patterns ENSG00000124102 ENSG00000182533 ENSG00000130528 ENSG00000156026 ENSG00000186716 PMC11284386__F1 Systemic and renal iron homeostasis ENSG00000178752 ENSG00000168610 PMC9331520__F3 Tumor microenvironment involvement in colorectal cancer progression via Wnt/Beta-catenin pathway: Providing understanding of the complex mechanisms of chemoresistance ENSG00000019991 ENSG00000107562 ENSG00000168036 PMC9331520__F4 Tumor microenvironment involvement in colorectal cancer progression via Wnt/Beta-catenin pathway: Providing understanding of the complex mechanisms of chemoresistance ENSG00000019991 ENSG00000134982 ENSG00000168036 PMC5399110__F9 A schematic representation or summary of the alteration in endothelial cell signaling by aberrant NOSTRIN expression ENSG00000102871 ENSG00000163072 ENSG00000175104 PMC10148646__F1 Molecular and Clinical Features of Hepatocellular Carcinoma in Patients with HBV-HDV Infection ENSG00000088305 ENSG00000086991 ENSG00000168036 PMC3091517__F2 Ras/PI3K/PTEN/Akt/mTOR Pathway and Potential Sites of Therapeutic Intervention ENSG00000169291 ENSG00000198793 ENSG00000155792 PMC3091517__F3 Interactions between the Ras/Raf/MEK/ERK, Ras/PI3K/PTEN/mTOR and Wnt/Beta-Catenin Pathways that Result in the Regulation of Protein Translation and Gene Transcription ENSG00000101115 PMC3091517__F1 Ras/Raf/MEK/ERK Pathway and Potential Sites of Therapeutic Intervention with Small Molecule Membrane-Permeable Inhibitors PMC7149907__F5 Oncogenic seRNA participates in carcinogenic processes through activating various signal-pathway ENSG00000136997 ENSG00000168036 ENSG00000146648 PMC8196994__F1 Altered Signal Transduction in the Immune Response to Influenza Virus and S. pneumoniae or S. aureus Co-Infections ENSG00000039537 ENSG00000288512 ENSG00000244731 ENSG00000166278 PMC9424846__F3 Assessing the suitability of long non-coding RNAs as therapeutic targets and biomarkers in SARS-CoV-2 infection PMC9424846__F4 Assessing the suitability of long non-coding RNAs as therapeutic targets and biomarkers in SARS-CoV-2 infection ENSG00000162594 ENSG00000125538 ENSG00000175104 ENSG00000168610 ENSG00000163702 PMC4102832__F2 Salinomycin: A Novel Anti-Cancer Agent with Known Anti-Coccidial Activities ENSG00000188486 ENSG00000281324 ENSG00000168036 PMC10742113__F1 Comparative signaling pathways mediated by adiponectin, leptin and resistin ENSG00000115138 ENSG00000159346 ENSG00000136869 ENSG00000285070 ENSG00000162692 ENSG00000168610 PMC7526619__F1 Omega-3 and omega-6 long-chain fatty acids synthesis pathways compete for the same enzymatic machinery in the cell ENSG00000118402 ENSG00000119915 ENSG00000066322 ENSG00000197977 ENSG00000166278 PMC10242764__F7 Molecular Mechanisms of Notopterygii rhizoma Et Radix for Treating Arrhythmia Based on Network Pharmacology ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000198793 ENSG00000042286 ENSG00000123374 ENSG00000112378 ENSG00000164305 PMC10742113__F2 Comparative signaling pathways of IL-6, PAI-1 and MCP-1 ENSG00000121807 ENSG00000168610 PMC3419619__F8 Protein kinase CD (PKCD) activation by proteolytic cleavage downstream of tumor necrosis factor (TNF) signaling in dopaminergic neurons ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC10242764__F5 Construction of drug-compound-target-pathway network ENSG00000039537 ENSG00000113600 ENSG00000166278 PMC6959184__F1 The role of MYD88 signaling in normal physiology and lymphomagenesis ENSG00000105369 ENSG00000186716 ENSG00000198793 ENSG00000134070 ENSG00000197943 ENSG00000175104 ENSG00000168610 ENSG00000184216 PMC12190641__F1 Study flowchart ENSG00000143061 ENSG00000100596 ENSG00000123505 PMC8599287__F7 USP25 Regulates the Proliferation and Apoptosis of Ovarian Granulosa Cells in Polycystic Ovary Syndrome by Modulating the PI3K/AKT Pathway via Deubiquitinating PTEN ENSG00000135446 ENSG00000155313 PMC8396448__F4 Pathogenesis and Therapeutic Approaches of Diabetic Neuropathy in the Retina ENSG00000115415 ENSG00000118515 ENSG00000128342 ENSG00000168610 PMC10742113__F5 Bacterial degradation of trimethylamine (TMA) for trimethylamine N-oxide (TMAO) formation ENSG00000162711 ENSG00000154059 PMC4425997__F1 The fundamental aspects of the DNA damage response pathway ENSG00000149311 ENSG00000175054 ENSG00000139618 PMC10742113__F3 Signaling pathway mediated by Escherichia coli lipopolysaccharides (LPSs) ENSG00000169047 ENSG00000172936 ENSG00000136869 ENSG00000162692 ENSG00000175104 ENSG00000026103 PMC8396448__F3 Pathogenesis and Therapeutic Approaches of Diabetic Neuropathy in the Retina ENSG00000278718 ENSG00000132906 ENSG00000128272 ENSG00000002330 ENSG00000102871 ENSG00000185591 ENSG00000168040 ENSG00000167182 ENSG00000127191 ENSG00000164305 ENSG00000084774 PMC7409273__F7 Proposed model of signaling pathways involved in HPV16 E7-mediated Pirin upregulation in oral epithelial cells ENSG00000087842 ENSG00000146648 PMC8904921__F5 Green Tea Polyphenols Upregulate the Nrf2 Signaling Pathway and Suppress Oxidative Stress and Inflammation Markers in D-Galactose-Induced Liver Aging in Mice ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC3670266__F1 Circulating miRNAs as new activators of the JAK-STAT3 pathway ENSG00000171150 ENSG00000168610 PMC8509312__F6 Inhibition of Mitochondrial Metabolism Leads to Selective Eradication of Cells Adapted to Acidic Microenvironment ENSG00000122966 ENSG00000172005 ENSG00000112992 PMC2823977__F1 REACTIVE OXYGEN SPECIES, CELLULAR REDOX SYSTEMS AND APOPTOSIS ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC3613593__F1 Hedgehog pathway ENSG00000180447 ENSG00000106571 ENSG00000112210 ENSG00000144857 ENSG00000128602 PMC6697777__F7 CaSR-mediated signaling and mesenteric artery relaxation ENSG00000214285 ENSG00000036828 ENSG00000134716 PMC8526712__F5 Signaling pathways in the regulation of cytokine release syndrome in human diseases and intervention therapy ENSG00000159128 ENSG00000110514 ENSG00000102871 ENSG00000027697 ENSG00000168040 ENSG00000105639 ENSG00000135341 ENSG00000127191 ENSG00000168610 ENSG00000115415 ENSG00000134070 ENSG00000172936 ENSG00000090376 ENSG00000184216 ENSG00000115594 PMC8430856__F2 Apoptosis Deregulation and the Development of Cancer Multi-Drug Resistance ENSG00000002330 ENSG00000005882 ENSG00000170855 PMC8430856__F1 Apoptosis Deregulation and the Development of Cancer Multi-Drug Resistance ENSG00000102871 PMC2684550__F2 In MSTN-null mice, regulators of the PI3K pathway and cell survival/apoptosis likely contribute to muscle hypertrophy ENSG00000089685 ENSG00000158828 PMC3855388__F4 CyTargetLinker: A Cytoscape App to Integrate Regulatory Interactions in Network Analysis ENSG00000169291 ENSG00000124882 ENSG00000135605 PMC3787240__F2 Selected non-epigenetic effects of sulforaphane and I3C/DIM on prostate cancer cells ENSG00000175793 ENSG00000198793 ENSG00000105810 ENSG00000171791 PMC5397262__F2 Misregulated expression of members of the ubiquitin cascade contributes to the aberrant signaling of various pathways in cancer ENSG00000135655 ENSG00000103266 ENSG00000134086 ENSG00000125826 ENSG00000244687 ENSG00000102871 ENSG00000285152 ENSG00000108106 ENSG00000123124 PMC9562180__F2 Macrophages, Chronic Inflammation, and Insulin Resistance ENSG00000102871 ENSG00000169047 ENSG00000172936 ENSG00000136869 ENSG00000127191 PMC4670915__F5 Scheme of the metabolic effect in control and differentiated SH-SY5Y cells ENSG00000142082 PMC8359344__F2 Multifaceted role of cell cycle regulators in the coordination of growth and metabolism ENSG00000228716 ENSG00000170522 ENSG00000077463 ENSG00000115419 ENSG00000026103 PMC8359344__F3 Multifaceted role of cell cycle regulators in the coordination of growth and metabolism ENSG00000134982 ENSG00000135446 ENSG00000006451 ENSG00000123374 ENSG00000265972 ENSG00000105810 ENSG00000171109 PMC4591129__F3 Microarray Analysis of the Gene Expression Profile and Lipid Metabolism in Fat-1 Transgenic Cattle ENSG00000150991 ENSG00000100979 ENSG00000165269 ENSG00000099194 PMC6791268__F2 Oncogenic activity of Bacteroides fragilis and Salmonella enterica ENSG00000081041 ENSG00000163739 ENSG00000168036 ENSG00000128602 ENSG00000168610 PMC10673274__F1 Sites of cellular PPi formation and details of galactose metabolism ENSG00000138777 PMC7840349__F2 Recent Updates of Lipoprotein(a) and Cardiovascular Disease ENSG00000003436 ENSG00000122194 ENSG00000135605 PMC8960856__F4 MicroRNAs in Serum Exosomes as Circulating Biomarkers for Postmenopausal Osteoporosis ENSG00000087095 ENSG00000095739 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000015285 ENSG00000148175 ENSG00000100211 PMC10914313__F7 The mechanism by which ARM promotes chemoresistance via PPARG/ABCG2 pathway ENSG00000135218 ENSG00000118777 PMC2484121__F2 Small Integrin-Binding LIgand N-linked Glycoproteins (SIBLINGs): Multifunctional proteins in cancer ENSG00000124102 ENSG00000026508 ENSG00000152592 PMC11978139__F2 Molecular processes underlying CXCL2 secretion ENSG00000081041 ENSG00000136869 ENSG00000168610 ENSG00000026103 PMC2725207__F3 Tale of two tails: Activation of DNA damage checkpoint kinase Mec1/ATR by the 9-1-1 clamp and by Dpb11/TopBP1 ENSG00000163918 ENSG00000133119 PMC3197364__F6 Hypothesized mechanisms for sphingolipids in cardioprotective signaling in response to ischemia or hypoxia ENSG00000157933 ENSG00000149269 PMC11953409__F1 Metabolic pathway shifts in T cells ENSG00000134982 PMC6283435__F3 TF cascades under glucagon control ENSG00000100811 ENSG00000112561 ENSG00000163884 PMC8574228__F5 Metabolic flexibility and HFpEF ENSG00000135218 ENSG00000096717 PMC8574228__F2 Fibrotic–inflammatory remodelling in heart failure with preserved ejection fraction ENSG00000087245 ENSG00000144935 ENSG00000149968 ENSG00000113140 ENSG00000291748 ENSG00000137672 ENSG00000100985 ENSG00000162692 ENSG00000108821 ENSG00000138741 ENSG00000168610 PMC8327170__F3 Mcl-1 Inhibition: Managing Malignancy in Multiple Myeloma ENSG00000131323 ENSG00000140443 PMC6146524__F4 Galactose metabolism, glycosylation and inflammatory cascades in galactosaemia ENSG00000109814 ENSG00000086848 ENSG00000128268 PMC8574228__F1 Signalling pathways in cardiac hypertrophy ENSG00000144935 ENSG00000198793 ENSG00000163914 ENSG00000169047 ENSG00000173786 ENSG00000117152 ENSG00000116741 ENSG00000137672 ENSG00000115271 ENSG00000142082 ENSG00000138741 PMC9353479__F6 Recapitulated Crosstalk between Cerebral Metastatic Lung Cancer Cells and Brain Perivascular Tumor Microenvironment in a Microfluidic Co‐Culture Chip ENSG00000198793 ENSG00000136997 ENSG00000146648 PMC8038842__F2 Human mitochondrial fatty acid biosynthesis (mtFAS) pathway ENSG00000121897 ENSG00000144182 ENSG00000175536 ENSG00000116353 ENSG00000137992 ENSG00000255154 ENSG00000176715 ENSG00000110435 ENSG00000100294 PMC4629004__F3 Changes in genes encoding components of the glycolytic, TCA cycle, and mitochondrial NADH shuttle pathways in gastrocnemius muscle in response to BCATm KO ENSG00000125166 ENSG00000130957 ENSG00000108515 ENSG00000073578 ENSG00000117118 ENSG00000288174 ENSG00000163541 ENSG00000105953 ENSG00000172340 ENSG00000143252 ENSG00000074800 ENSG00000100412 ENSG00000292099 ENSG00000164708 ENSG00000146701 ENSG00000091140 ENSG00000159399 ENSG00000141526 ENSG00000152556 ENSG00000062485 PMC4408550__F1 Activation of TGFB requires liberation of the TGFB dimer from an inactive latent complex with the LAP ENSG00000140564 ENSG00000122194 PMC4629004__F2 BCATm KO on protein synthesis pathways ENSG00000280831 ENSG00000131469 ENSG00000291931 ENSG00000124614 ENSG00000105193 ENSG00000169047 ENSG00000116251 ENSG00000063177 ENSG00000066027 ENSG00000149273 ENSG00000149806 ENSG00000166441 ENSG00000108298 ENSG00000164587 ENSG00000130811 ENSG00000278270 ENSG00000105568 ENSG00000104408 ENSG00000083845 ENSG00000172809 ENSG00000161016 ENSG00000100353 ENSG00000175390 ENSG00000182774 ENSG00000073711 ENSG00000182899 ENSG00000213741 ENSG00000197728 ENSG00000138326 ENSG00000171863 ENSG00000125691 ENSG00000008988 ENSG00000134419 ENSG00000184110 ENSG00000168028 ENSG00000168209 ENSG00000223367 ENSG00000115268 ENSG00000100664 ENSG00000086232 ENSG00000163435 ENSG00000142541 ENSG00000174748 ENSG00000144895 ENSG00000241343 ENSG00000106263 ENSG00000129824 ENSG00000149100 ENSG00000163590 ENSG00000112306 PMC8613644__F2 Cell-free network communication in alcohol-associated disorders and liver metastasis ENSG00000041353 ENSG00000128016 ENSG00000163235 ENSG00000178209 ENSG00000204673 ENSG00000173083 ENSG00000197386 ENSG00000197381 ENSG00000137575 ENSG00000123595 PMC4278286__F4 Altered metabolic pathways in clear cell renal cell carcinoma: A meta-analysis and validation study focused on the deregulated genes and their associated networks ENSG00000107798 ENSG00000112715 ENSG00000168610 ENSG00000230034 ENSG00000073060 ENSG00000188313 ENSG00000115415 ENSG00000115457 ENSG00000170458 ENSG00000107485 ENSG00000185591 ENSG00000136872 ENSG00000116218 ENSG00000024422 ENSG00000061656 ENSG00000074803 PMC3895605__F2 Possible signalling pathways involved in enteric neurogenesis by a 5-hydroxytryptamine 4 receptor (5-HT4R) agonist mosapride citrate (MOS) ENSG00000136158 ENSG00000066735 ENSG00000123144 ENSG00000172680 ENSG00000070831 ENSG00000163914 ENSG00000136160 ENSG00000124205 PMC8699756__F3 Transcriptome Analysis in Vulvar Squamous Cell Cancer ENSG00000094880 ENSG00000141552 ENSG00000105401 ENSG00000197471 ENSG00000263042 ENSG00000100842 ENSG00000112118 ENSG00000205250 ENSG00000073111 ENSG00000164162 ENSG00000117399 ENSG00000093009 ENSG00000149311 ENSG00000105325 ENSG00000114126 ENSG00000176248 ENSG00000136997 ENSG00000004897 PMC3703268__F6 Network view of TGF-beta signaling pathway alterations in colorectal and ovarian cancer ENSG00000284774 ENSG00000101367 ENSG00000005339 ENSG00000157077 ENSG00000134982 ENSG00000214078 ENSG00000221914 ENSG00000147789 ENSG00000101057 ENSG00000065559 ENSG00000118707 ENSG00000120885 ENSG00000169032 ENSG00000135341 ENSG00000136603 ENSG00000160973 ENSG00000136997 ENSG00000173334 PMC6685260__F5 Molecular characterization of subpathway signatures ENSG00000065135 ENSG00000082175 ENSG00000078369 ENSG00000034713 ENSG00000167083 ENSG00000213341 PMC10743556__F2 Keap1/Nrf2/ARE signaling pathway ENSG00000181019 ENSG00000079999 PMC3188957__F4 Highest confidence network of genes influenced by CLOCK knockdown ENSG00000135218 ENSG00000275190 ENSG00000197888 ENSG00000163993 ENSG00000196620 ENSG00000128268 PMC3534992__F7 MiR-146b function in IEC-6 cells mediating TGFB signaling ENSG00000181788 PMC8039382__F2 Metabolic and signaling networks involved in anoikis-resistance mechanism ENSG00000198793 ENSG00000136997 ENSG00000169710 ENSG00000168610 ENSG00000146648 PMC8103695__F5 Evaluating a New Class of AKT/mTOR Activators for HIV Latency-Reversing Activity Ex Vivo and In Vivo ENSG00000169047 ENSG00000155792 PMC4170681__F1 The genetic signatures of pediatric high-grade glioma: no longer a one-act play ENSG00000112576 ENSG00000135446 ENSG00000105810 ENSG00000118971 PMC4882600__F8 RhBMP-2 Activates Hippo Signaling through RASSF1 in Esophageal Cancer Cells ENSG00000068028 ENSG00000135446 ENSG00000105810 ENSG00000150457 ENSG00000131023 PMC8088956__F2 Dysregulation of Wnt/B‐catenin signaling by protein kinases in hepatocellular carcinoma and its therapeutic application ENSG00000087095 ENSG00000019991 ENSG00000117650 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000138798 ENSG00000168036 ENSG00000146648 ENSG00000130669 PMC6165531__F1 The sugar metabolism (green) and signaling (blue) pathways ENSG00000147162 ENSG00000090104 ENSG00000214253 PMC3089884__F5 Chemokine Signaling Pathway ENSG00000166349 ENSG00000169291 ENSG00000120885 PMC7603127__F2 NRF2 directs numerous metabolic processes that impact cancer cell survival and proliferation, including NADPH production and the metabolism of lipids, amino acids, nucleotides, and iron/heme (a) ENSG00000284320 ENSG00000065833 ENSG00000065911 ENSG00000066926 ENSG00000092621 ENSG00000167468 ENSG00000135069 ENSG00000023909 ENSG00000070669 ENSG00000115419 ENSG00000026103 PMC9406467__F3 Targeting Histone Epigenetic Modifications and DNA Damage Responses in Synthetic Lethality Strategies in Cancer? ENSG00000149311 ENSG00000100749 ENSG00000183765 PMC4935811__F3 Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards ENSG00000168329 ENSG00000140968 ENSG00000118520 PMC4736825__F4 Model of translational repression of Nodal pathway components ENSG00000163435 ENSG00000065978 ENSG00000156574 ENSG00000173578 PMC6393772__F6 Carcinogenesis and Reactive Oxygen Species Signaling: Interaction of the NADPH Oxidase NOX1–5 and Superoxide Dismutase 1–3 Signal Transduction Pathways ENSG00000169554 ENSG00000157764 ENSG00000291971 ENSG00000170558 PMC6393772__F7 Carcinogenesis and Reactive Oxygen Species Signaling: Interaction of the NADPH Oxidase NOX1–5 and Superoxide Dismutase 1–3 Signal Transduction Pathways ENSG00000157764 ENSG00000291971 ENSG00000168036 PMC7432012__F3 Tumor necrosis factor beta (TNFA), interleukin 1 beta (IL-1B), bone morphogenetic protein (BMP), and transforming growth factor beta (TGFB) are stiffness-dependent signaling pathways ENSG00000170365 ENSG00000162551 ENSG00000125538 PMC3931462__F8 Proteolytic cleavage of CDCP1 contributes to enhanced tumor cell survival and motility through the FAK and Akt signaling pathways downstream of complex formation between cleaved CDCP1 and B1 integrin ENSG00000291971 ENSG00000163814 ENSG00000122194 PMC7432012__F4 Material stiffness-induced Wnt signaling ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9534854__F9 BNC1-Merlin-Hippo-YAP signaling -Ferroptosis axis ENSG00000169594 ENSG00000186575 ENSG00000167468 ENSG00000150457 ENSG00000131023 PMC6393772__F2 Carcinogenesis and Reactive Oxygen Species Signaling: Interaction of the NADPH Oxidase NOX1–5 and Superoxide Dismutase 1–3 Signal Transduction Pathways ENSG00000140992 ENSG00000106683 ENSG00000163914 PMC8750485__F1 Therapeutic Potential of Emerging NAD+-Increasing Strategies for Cardiovascular Diseases ENSG00000105835 PMC11847137__F9 Schemic working model revealing the possible role of ZC3H15 in mediating BCP ENSG00000181019 ENSG00000065548 ENSG00000079999 PMC5604081__F1 Regulation of intrinsic cancer metabolism by obesity-associated growth factors ENSG00000131473 ENSG00000198793 ENSG00000136997 ENSG00000159399 ENSG00000140443 ENSG00000062485 ENSG00000026103 PMC9434279__F1 Research progress on the mechanism of beta-cell apoptosis in type 2 diabetes mellitus ENSG00000121351 ENSG00000125538 PMC3732476__F2 Notch signaling pathway ENSG00000283780 ENSG00000137845 PMC7555059__F1 Hierarchy of repair pathways choice in mammalian cell ENSG00000012048 ENSG00000051180 ENSG00000177084 ENSG00000310560 ENSG00000139618 PMC6240761__F1 Hypothalamic-pituitary-adrenal axis signaling ENSG00000108691 ENSG00000112964 ENSG00000145321 ENSG00000121807 ENSG00000146648 PMC7555059__F4 Proposed antagonistic relationship of 53BP1 and BRCA1 during DSB repair pathway choice based on DNA resection ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000080345 PMC3121899__F3 Cartoons of PAR-1-dependent signaling by APC and thrombin in endothelial cells when EPCR is either free or occupied by protein C ENSG00000173599 PMC2806113__F6 Working model of TGFB actions in renal interstitial fibrogenesis ENSG00000198793 PMC6719047__F2 RTT-related protein known functional interaction networks ENSG00000136531 ENSG00000196498 ENSG00000179456 ENSG00000100346 ENSG00000081189 ENSG00000177842 ENSG00000008853 ENSG00000103942 ENSG00000196367 ENSG00000111642 PMC6518824__F3 Schematic indicating the pathway from Micronucleus formation to activation of the cGAS-STING pathway, and canonical and non-canonical routes to Type I interferon response ENSG00000104856 ENSG00000164430 PMC9629402__F7 In Silico and In Vitro studies of taiwan chingguan yihau (NRICM101) on TNFA/IL-1Beta-induced human lung cells ENSG00000162889 ENSG00000170458 ENSG00000177606 ENSG00000169429 ENSG00000108821 ENSG00000175104 ENSG00000135341 ENSG00000127191 ENSG00000123610 PMC7690798__F2 Functional interaction network and molecular classes of the 20 genes with high RNAi efficacy from ENSG00000144028 ENSG00000155506 ENSG00000167088 ENSG00000147604 ENSG00000167658 ENSG00000168036 ENSG00000188846 ENSG00000145592 ENSG00000104408 ENSG00000274808 ENSG00000177700 ENSG00000031698 ENSG00000134419 ENSG00000100387 ENSG00000106263 ENSG00000087365 ENSG00000164362 ENSG00000196365 ENSG00000146648 ENSG00000132341 PMC6438456__F10 Review: Precision medicine and driver mutations: Computational methods, functional assays and conformational principles for interpreting cancer drivers ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000164327 ENSG00000167965 ENSG00000146648 PMC6535785__F7 Probable molecular mechanistic pathway of ruthenium baicalein complex ENSG00000132646 ENSG00000198793 ENSG00000164305 PMC5312370__F6 RAD51 inhibition in triple negative breast cancer cells is challenged by compensatory survival signaling and requires rational combination therapy ENSG00000143799 ENSG00000198793 ENSG00000051180 ENSG00000168610 PMC8436408__F1 Improving the Adjuvanticity of Small Molecule Immune Potentiators Using Covalently Linked NFKB Modulators PMC4447524__F1 Resistance to BCR-ABL1 tyrosine kinase inhibitors may take the form of (left) point or compound mutation-based, BCR-ABL1-dependent resistance or (middle) recruitment of alternative pathway signaling upon effective inhibition of BCR-ABL1 ENSG00000291971 ENSG00000168610 ENSG00000127948 PMC2956608__F1 Inhibition of the type I interferon (IFN) pathway of Kaposi's sarcoma-associated herpesvirus (KSHV) ENSG00000183735 ENSG00000170458 ENSG00000276561 PMC8453146__F2 Kill and Clearance in HCC: An Approach Based on NK Cells and Macrophages ENSG00000168329 ENSG00000108691 ENSG00000118520 ENSG00000277943 PMC6616015__F2 Gene-gene interaction networks ENSG00000144063 ENSG00000146376 ENSG00000101280 ENSG00000162924 ENSG00000146143 ENSG00000141527 ENSG00000112414 ENSG00000157927 ENSG00000104756 ENSG00000060709 ENSG00000172031 ENSG00000198435 ENSG00000273772 ENSG00000197444 ENSG00000100426 ENSG00000123374 PMC2921274__F2 Eph receptors and ephrins in cancer: bidirectional signaling and beyond ENSG00000142627 ENSG00000291971 ENSG00000133216 PMC7390515__F2 TGFB signaling in health and disease PMC8699427__F2 Recent Advances in Adipose Tissue Dysfunction and Its Role in the Pathogenesis of Non-Alcoholic Fatty Liver Disease ENSG00000150782 ENSG00000132326 ENSG00000179094 PMC2082051__F5 Networks of pathways unique in the HIV-1 regulated mPBMCs ENSG00000011600 ENSG00000291603 ENSG00000157764 ENSG00000122223 ENSG00000163599 ENSG00000205809 ENSG00000277263 ENSG00000281877 PMC4920181__F5 An illustration showing roles or functions of analyzed retinal disease-related genes ENSG00000134376 ENSG00000116745 ENSG00000105392 ENSG00000166402 ENSG00000174804 ENSG00000092200 ENSG00000132518 ENSG00000124479 ENSG00000104237 ENSG00000111837 ENSG00000198570 ENSG00000183638 ENSG00000150275 ENSG00000144061 ENSG00000048342 ENSG00000281857 ENSG00000042781 ENSG00000168263 ENSG00000164342 PMC10859375__F5 Lipid laden macrophage accumulation in the p ENSG00000166819 ENSG00000151726 ENSG00000135218 ENSG00000119655 ENSG00000167676 ENSG00000099194 ENSG00000062282 PMC7542331__F5 Regulatory loops around TGFB1 link important transcription factors and cytokines ENSG00000124216 ENSG00000119138 ENSG00000105329 ENSG00000122691 ENSG00000150907 ENSG00000288335 ENSG00000020633 ENSG00000127528 PMC6465591__F1 Lymphatic vessel functions during tumor progression ENSG00000107562 ENSG00000137077 ENSG00000126353 ENSG00000162692 ENSG00000121966 ENSG00000150630 PMC1087229__F8 Signaling pathway of NGF-induced neurite outgrowth in PC12 cells ENSG00000070831 ENSG00000134215 ENSG00000115904 ENSG00000160293 PMC5293580__F5 Leucine alleviates dexamethasone-induced suppression of muscle protein synthesis via synergy involvement of mTOR and AMPK pathways ENSG00000011566 ENSG00000198793 PMC11622859__F4 Reconstitution of the biosynthetic pathway of CNs in this work and the semi-synthesis of ISIR-050 ENSG00000197429 PMC5386521__F1 Scheme depicting a molecular pathway by which Cdc25A is induced/activated and promotes neuron death in disease and development ENSG00000135446 PMC3606047__F1 Adenosine Signaling During Acute and Chronic Disease States ENSG00000170425 ENSG00000106546 PMC2921274__F4 Eph receptors and ephrins in cancer: bidirectional signaling and beyond ENSG00000010810 PMC7214542__F1 Regulatory and catabolic pathways for glucose and xylose metabolism in E ENSG00000261701 ENSG00000197487 ENSG00000150787 ENSG00000132693 PMC3241422__F10 Control of Rho1 activity through the cell cycle ENSG00000149489 PMC3724215__F1 IGF pathway ENSG00000171105 ENSG00000002330 ENSG00000197081 ENSG00000198793 ENSG00000187840 ENSG00000140443 ENSG00000160691 PMC7972191__F7 Graphic abstract showing how the KPNA2/CBX8/PRDM1/c-FOS pathway works in BCa ENSG00000182481 ENSG00000183337 ENSG00000141570 PMC5870182__F6 Schematic diagram illustrating the mechanism of WYHZTL formula in regulating Wnt/Beta-catenin signaling pathway ENSG00000134982 ENSG00000168036 PMC12163303__F2 Mechanisms of translation regulation ENSG00000284161 ENSG00000167658 PMC3426818__F5 MUC5B gene expression is transcriptionally regulated by various mediators and pathways ENSG00000065361 ENSG00000125538 ENSG00000185591 ENSG00000112115 ENSG00000117983 PMC9623415__F1 PKC-mediated phosphorylation and activation of the MEK/ERK pathway as a mechanism of acquired trastuzumab resistance in HER2-positive breast cancer ENSG00000198793 PMC4240652__F6 Transcriptome Analysis on the Inflammatory Cell Infiltration of Nonalcoholic Steatohepatitis in Bama Minipigs Induced by a Long-Term High-Fat, High-Sucrose Diet ENSG00000186810 ENSG00000169291 ENSG00000156299 ENSG00000105639 PMC4240652__F8 Transcriptome Analysis on the Inflammatory Cell Infiltration of Nonalcoholic Steatohepatitis in Bama Minipigs Induced by a Long-Term High-Fat, High-Sucrose Diet ENSG00000110395 ENSG00000213658 ENSG00000117091 ENSG00000134982 ENSG00000198851 ENSG00000010810 ENSG00000135446 ENSG00000134215 ENSG00000163599 ENSG00000113520 ENSG00000113263 PMC11002873__F3 Working model for the Wnt, TGFB, and Pax6 signalling in the regulation of ciliary body development ENSG00000170365 ENSG00000138795 ENSG00000120149 ENSG00000163132 ENSG00000168646 PMC4163376__F2 Simplified overview of the Rb/E2F pathway ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000166508 PMC3148569__F6 Perturbed TGFB/Smad and mitogen-activated protein kinase signalling pathways in Dupuytren's fibroblasts ENSG00000156574 PMC7520270__F5 Enrichment and functional annotation by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) ENSG00000182718 ENSG00000142627 ENSG00000164904 ENSG00000112972 ENSG00000067057 ENSG00000105438 ENSG00000137501 ENSG00000152527 ENSG00000198648 ENSG00000133195 ENSG00000102931 ENSG00000173402 ENSG00000150991 ENSG00000101003 ENSG00000143320 ENSG00000108384 ENSG00000167996 ENSG00000117620 ENSG00000110911 PMC8458764__F1 Metabolic Contributions of Wnt Signaling: More Than Controlling Flight ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000134982 ENSG00000168036 PMC5858703__F4A Retinoic acid-related Orphan Receptor G (RORG): connecting sterol metabolism to regulation of the immune system and autoimmune disease ENSG00000162594 ENSG00000073754 ENSG00000168610 PMC7764399__F2 Various gut microbial stimuli due to dysbiosis can cause the initiation of inflammation in the intestine ENSG00000162594 ENSG00000162711 ENSG00000187796 ENSG00000237693 PMC8458764__F2 Metabolic Contributions of Wnt Signaling: More Than Controlling Flight ENSG00000134982 ENSG00000168036 PMC7284378__F5 Proposed mechanisms for protective effects of MWF on chronic alcohol-induced liver injury ENSG00000113161 ENSG00000198670 ENSG00000120437 PMC8882905__F4 Antiplatelet Therapy in Patients With MINOCA ENSG00000115008 ENSG00000110799 PMC5963346__F3 DEGs associated with TNF signaling pathway at different time points after cerebral ischemia ENSG00000168404 ENSG00000164305 PMC9623415__F2 PKC-mediated phosphorylation and activation of the MEK/ERK pathway as a mechanism of acquired trastuzumab resistance in HER2-positive breast cancer ENSG00000135446 ENSG00000198793 ENSG00000168036 PMC6462347__F5 Schematic overview of the folate metabolic pathway mediated by FOLR, DHFR, and MTRR ENSG00000228716 ENSG00000124275 ENSG00000116984 PMC4803789__F2 Molecular regulation of autophagy ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000198382 ENSG00000144848 ENSG00000157954 ENSG00000171791 ENSG00000145782 ENSG00000057663 PMC12006828__F15 Biosynthetic gene cluster and (B) proposed biosynthetic pathway of stipitatic acid ENSG00000158526 ENSG00000167721 ENSG00000007520 PMC7002875__F8 KDM5C is a SAHA-sensitive marker of a druggable pathway damaged in NDDs ENSG00000136531 ENSG00000004848 ENSG00000008056 ENSG00000126012 PMC12006828__F11 Biosynthetic gene clusters and (B) the proposed biosynthetic pathways of helvamide B and arizonamides ENSG00000175054 ENSG00000227345 PMC6441734__F6 JNK pathways in mammals and drosophila ENSG00000065833 PMC3575449__F1 From photomorphogenesis to cancer ENSG00000145604 ENSG00000171209 PMC6477797__F6 Biological pathways associated with non-synonymously mutated genes in TCL1 mice ENSG00000124102 ENSG00000104365 ENSG00000117525 ENSG00000291987 ENSG00000181163 ENSG00000102034 ENSG00000186716 ENSG00000198793 ENSG00000184634 ENSG00000131323 ENSG00000135424 ENSG00000146648 PMC6322364__F7 TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress ENSG00000116001 ENSG00000012048 ENSG00000175054 ENSG00000144554 ENSG00000132646 PMC8436938__F13 Siberian fir terpenes extract Abisil on antioxidant activity, autophagy, transcriptome and proteome of human fibroblasts ENSG00000118007 ENSG00000108055 ENSG00000205250 ENSG00000091651 ENSG00000277273 ENSG00000117399 ENSG00000093009 ENSG00000145604 ENSG00000094804 ENSG00000101972 ENSG00000135446 ENSG00000132646 ENSG00000115942 ENSG00000125686 ENSG00000135336 ENSG00000123374 ENSG00000105810 PMC4256277__F4 Epigenome-Guided Analysis of the Transcriptome of Plaque Macrophages during Atherosclerosis Regression Reveals Activation of the Wnt Signaling Pathway ENSG00000125166 ENSG00000138346 ENSG00000281324 ENSG00000175866 ENSG00000162337 ENSG00000131446 ENSG00000291971 ENSG00000109113 ENSG00000055483 ENSG00000099377 ENSG00000109654 ENSG00000167130 ENSG00000168961 ENSG00000160752 ENSG00000113719 ENSG00000174600 ENSG00000130052 ENSG00000058262 ENSG00000272573 ENSG00000169696 ENSG00000184436 PMC4256277__F2 Epigenome-Guided Analysis of the Transcriptome of Plaque Macrophages during Atherosclerosis Regression Reveals Activation of the Wnt Signaling Pathway ENSG00000132423 ENSG00000140157 ENSG00000175866 ENSG00000109113 ENSG00000291971 ENSG00000182899 ENSG00000104142 ENSG00000198793 ENSG00000099377 ENSG00000167130 ENSG00000138964 ENSG00000157184 ENSG00000163914 ENSG00000176894 ENSG00000110108 ENSG00000109654 ENSG00000113719 ENSG00000130052 ENSG00000169696 ENSG00000084090 ENSG00000170791 ENSG00000137460 ENSG00000147576 ENSG00000203705 ENSG00000197562 ENSG00000115165 ENSG00000084774 ENSG00000137474 PMC3596326__F4 Structural Phylogenomics Reveals Gradual Evolutionary Replacement of Abiotic Chemistries by Protein Enzymes in Purine Metabolism PMC3805607__F3 Comparative Transcriptional Profiling of 3 Murine Models of SLE Nephritis Reveals Both Unique and Shared Regulatory Networks ENSG00000126231 ENSG00000148450 ENSG00000164062 ENSG00000242110 ENSG00000085514 ENSG00000089472 ENSG00000164399 ENSG00000112715 ENSG00000105607 ENSG00000048740 ENSG00000166592 ENSG00000184500 ENSG00000111341 ENSG00000100979 ENSG00000177084 ENSG00000087245 ENSG00000010704 ENSG00000178078 ENSG00000169896 ENSG00000063854 ENSG00000162551 ENSG00000113140 ENSG00000173039 ENSG00000110876 ENSG00000067606 PMC4760780__F7 Proposed model for Usp12 function in the pathway of TCR signaling ENSG00000152484 ENSG00000213658 ENSG00000163519 ENSG00000109189 PMC5732848__F1 Environment Matters: Microglia Function and Dysfunction in a Changing World PMC8465283__F1 p53 mRNA Metabolism Links with the DNA Damage Response ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000276618 ENSG00000116717 ENSG00000142731 ENSG00000140464 ENSG00000122008 PMC3805607__F2 Comparative Transcriptional Profiling of 3 Murine Models of SLE Nephritis Reveals Both Unique and Shared Regulatory Networks ENSG00000104856 ENSG00000065911 ENSG00000011600 ENSG00000105329 ENSG00000143878 ENSG00000181104 ENSG00000291803 ENSG00000078070 ENSG00000168610 ENSG00000070669 ENSG00000135905 ENSG00000166428 ENSG00000108691 ENSG00000115956 ENSG00000109861 ENSG00000103490 ENSG00000145623 ENSG00000122971 ENSG00000126458 ENSG00000189067 PMC9709205__F3 Impact of SOX2 function and regulation on therapy resistance in bladder cancer ENSG00000146678 PMC10417115__F2 miRNA binding sites at the rs8720 and rs12587 variants of the KRAS gene and their function in tumor regulation ENSG00000185591 PMC3947785__F1 What’s the Mtrr with your grandparents? ENSG00000180210 ENSG00000117525 ENSG00000124275 ENSG00000116984 PMC9532536__AF1 Cucurbitacin B-induced G2/M cell cycle arrest of conjunctival melanoma cells mediated by GRP78–FOXM1–KIF20A pathway ENSG00000134057 ENSG00000112984 ENSG00000175899 ENSG00000166851 PMC3567816__F1 A summary of the newly proposed inflammasome activation pathway including PKRs' recently found role ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000091592 ENSG00000189403 ENSG00000091106 PMC8003318__F2 miR-29a and HCC carcinogenesis ENSG00000073584 ENSG00000120868 PMC8003318__F3 miR-29a as an epigenetic modifier ENSG00000187605 ENSG00000138336 ENSG00000143379 ENSG00000100985 ENSG00000081051 PMC8003318__F4 Role and mechanism of miR-29a in metabolic adaptation ENSG00000113140 ENSG00000096717 PMC8003318__F5 ceRNA acts as miR-29a sponge to positively promote HCC progression ENSG00000253352 PMC8003318__F6 miR-29a as a regulator of tumor microenvironment ENSG00000134013 ENSG00000142089 ENSG00000112715 ENSG00000168610 ENSG00000140443 PMC8405630__F4 Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy ENSG00000149311 ENSG00000175054 ENSG00000278494 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000101224 PMC5030232__F7 Major metabolic pathways anticipated to participate in spore germination process in N ENSG00000156110 ENSG00000153574 PMC6473282__F6 Proposed regulatory mechanism of estrogen in colitis-associated colorectal cancer at week 2 (A) and at weeks 10 and 16 (B) ENSG00000162711 ENSG00000023909 PMC5435615__F5 Diagram of heme effect ENSG00000162711 ENSG00000065559 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000265972 ENSG00000131323 ENSG00000130159 ENSG00000150455 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC4116803__F1 Improving GD T cell functions by TLRs in combinatorial therapy ENSG00000197429 ENSG00000204520 PMC8301900__F3 Protein Phosphorylation in Cancer: Role of Nitric Oxide Signaling Pathway ENSG00000002330 ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC6834161__F2 Working model of FH physiopathology and the effects of CoQ ENSG00000130164 ENSG00000169174 PMC7882549__F2 Mevalonate pathway and possible mechanism of action of statins ENSG00000163914 ENSG00000171791 ENSG00000146648 PMC6617458__F3 Microbial N-cycle and chitin convergence and degradation pathway mediated through the addition of chitin ENSG00000151657 ENSG00000105402 PMC8944541__F5 Venetoclax-Resistant MV4-11 Leukemic Cells Activate PI3K/AKT Pathway for Metabolic Reprogramming and Redox Adaptation for Survival ENSG00000163064 ENSG00000164778 PMC6607732__F1 STING pathway activation in DNA repair deficient breast cancer ENSG00000169245 ENSG00000183735 ENSG00000089692 ENSG00000164430 ENSG00000163599 ENSG00000049768 PMC5431893__F1 Pathway of “aryl hydrocarbon receptor signaling”-initiated smoking-related cancer ENSG00000137834 ENSG00000120875 ENSG00000171759 ENSG00000127616 ENSG00000106546 PMC7506147__F1 In the cytoplasm, PTEN mediates dephosphorylation of PIP3 to PIP 2 which inhibits the PI3k/Akt/mTOR signaling pathway leading to slower tumor growth ENSG00000168283 ENSG00000198793 PMC4442271__F1 Obesity, immunomodulation and chronic kidney disease ENSG00000226275 ENSG00000166278 PMC7998562__F1 Complement activation pathways ENSG00000039537 ENSG00000113600 ENSG00000196352 ENSG00000117335 ENSG00000244731 ENSG00000166278 ENSG00000074266 ENSG00000236625 PMC10311182__F1 Key piece of the airway remodeling puzzle revealed—LIGHT signaling in the lung ENSG00000104856 ENSG00000111321 ENSG00000131323 ENSG00000127191 PMC8864109__F6 lncRNA Mirt1: A Critical Regulatory Factor in Chronic Intermittent Hypoxia Exaggerated Post-MI Cardiac Remodeling ENSG00000169554 ENSG00000162551 ENSG00000132259 ENSG00000104833 ENSG00000151532 ENSG00000091879 ENSG00000163295 ENSG00000101680 ENSG00000164105 ENSG00000163914 ENSG00000152785 ENSG00000196092 ENSG00000171540 ENSG00000180875 ENSG00000123908 PMC8289790__F1 Metabolic reprogramming of T regulatory cells in the hypoxic tumor microenvironment ENSG00000198793 ENSG00000049768 ENSG00000168610 PMC8289790__F2 Metabolic reprogramming of T regulatory cells in the hypoxic tumor microenvironment ENSG00000198793 ENSG00000049768 PMC6429583__F2 Homology of the GSH synthesis pathways in mammals and Caenorhabditis elegans ENSG00000145321 ENSG00000023909 PMC3670113__F1 Role of SHIP1 in bone biology ENSG00000124102 ENSG00000109452 ENSG00000162607 ENSG00000168036 PMC2842081__F1 Telomeres: protecting chromosomes against genome instability ENSG00000166340 ENSG00000149311 ENSG00000175054 ENSG00000130826 ENSG00000165392 ENSG00000164362 ENSG00000197299 ENSG00000128513 PMC5842023__F8 T cell receptor signaling pathways in eosinophilic asthma ENSG00000291603 ENSG00000110395 ENSG00000213658 ENSG00000117091 ENSG00000010810 ENSG00000135446 ENSG00000113263 PMC6888549__F1 Wnt signaling pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000168036 PMC6547487__F5 Functional significance of several key genes from four KEGG pathways differentially expressed in female and male magpies ENSG00000149311 ENSG00000159216 ENSG00000213658 ENSG00000134982 ENSG00000177606 ENSG00000284161 ENSG00000069667 PMC6189633__F3 Expression of microRNAs and target proteins in skeletal muscle of rats selectively bred for high and low running capacity ENSG00000138613 ENSG00000050748 ENSG00000178741 ENSG00000182606 ENSG00000164305 ENSG00000123472 ENSG00000062485 PMC5522964__F1 Epithelial to mesenchymal transition (EMT)-inducing transcription factors and the reported E3 ubiquitin ligases that govern their stability ENSG00000174989 ENSG00000171823 PMC5832878__F7 DAX1 promotes cervical cancer cell growth and tumorigenicity through activation of Wnt/Beta-catenin pathway via GSK3B ENSG00000134982 ENSG00000168036 PMC6890794__F7 Summary of changes to the Wnt pathway as a result of AD + TS treatment ENSG00000026508 ENSG00000168036 ENSG00000168610 ENSG00000164305 PMC2657106__F1 Activation of the G2/M checkpoint after DNA damage ENSG00000149311 ENSG00000175054 ENSG00000134982 ENSG00000166851 ENSG00000276876 PMC8859819__F4 Epigenetic regulation of inflammation by microRNAs in post‐infectious bronchiolitis obliterans ENSG00000157404 ENSG00000153094 ENSG00000139269 ENSG00000169047 ENSG00000115904 ENSG00000108443 ENSG00000187266 ENSG00000112715 ENSG00000121807 ENSG00000144476 ENSG00000142166 ENSG00000137080 ENSG00000122025 ENSG00000039319 ENSG00000131142 ENSG00000145623 ENSG00000113558 ENSG00000128052 ENSG00000163734 ENSG00000169429 ENSG00000006606 ENSG00000145782 ENSG00000176165 ENSG00000140443 ENSG00000106178 ENSG00000107779 ENSG00000139193 ENSG00000081041 ENSG00000005339 ENSG00000183691 ENSG00000163736 ENSG00000067900 ENSG00000166090 ENSG00000173530 ENSG00000145604 ENSG00000108691 ENSG00000161921 ENSG00000126353 ENSG00000112115 ENSG00000171608 ENSG00000096717 ENSG00000204217 ENSG00000115009 ENSG00000114739 PMC9194136__F5 Exploring the metabolic landscape of pancreatic ductal adenocarcinoma cells using genome-scale metabolic modeling ENSG00000125166 ENSG00000131473 ENSG00000065833 ENSG00000172005 ENSG00000169710 PMC6120815__F1 Innate Immune Signaling and Alcohol Use Disorders ENSG00000111537 ENSG00000189403 ENSG00000136869 ENSG00000121807 ENSG00000175104 ENSG00000276561 PMC7407180__F5 Proposed biosynthetic pathway leading to terpenoids in A ENSG00000110921 ENSG00000197429 PMC4398671__F8 Schema of structure and signaling pathway of G-CSFRI and G-CSFRIV ENSG00000108691 ENSG00000164938 PMC2667983__F4 Winter Temperature and UV Are Tightly Linked to Genetic Changes in the p53 Tumor Suppressor Pathway in Eastern Asia ENSG00000128342 ENSG00000078237 ENSG00000284194 PMC8224255__F2 Efficacy of phytochemicals as immunomodulators in managing COVID-19: a comprehensive view ENSG00000130234 PMC8883632__F10 Abundant expression of ferroptosis-related SAT1 is related to unfavorable outcome and immune cell infiltration in low-grade glioma ENSG00000161905 ENSG00000111537 PMC9382640__F2 Mechanisms and prospects of circular RNAs and their interacting signaling pathways in colorectal cancer ENSG00000198793 PMC7666199__F4 Reconstructed hydrogenotrophic methanogenesis metabolic pathway with associated carbon fixation through the reductive Acetyl-CoA pathway, methane metabolism and coenzyme biosynthesis by Methanobacterium sp ENSG00000127948 ENSG00000116984 PMC5244562__F1 Scheme of PI3K pathway with candidate regulators of mTORC2 colored in green ENSG00000169047 ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC4433776__F1 HHLA2 interaction with two receptors to regulate T cell functions ENSG00000167664 ENSG00000114455 ENSG00000134982 PMC5915062__F4 Proteomic alterations in early stage cervical cancer ENSG00000117228 ENSG00000186395 ENSG00000131747 ENSG00000134757 ENSG00000081277 ENSG00000046604 ENSG00000134755 ENSG00000159720 ENSG00000167880 ENSG00000163207 ENSG00000143320 ENSG00000135446 ENSG00000105810 ENSG00000118898 PMC5915062__F5 Proteomic alterations in early stage cervical cancer ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000166508 ENSG00000100714 ENSG00000102081 ENSG00000171861 ENSG00000132646 ENSG00000153147 ENSG00000171848 ENSG00000138162 ENSG00000133119 ENSG00000253729 ENSG00000137055 PMC5915062__F2 Proteomic alterations in early stage cervical cancer ENSG00000047410 ENSG00000141568 ENSG00000112118 ENSG00000035928 ENSG00000076003 ENSG00000073614 ENSG00000198554 ENSG00000115942 ENSG00000163993 ENSG00000136504 ENSG00000196642 ENSG00000100219 ENSG00000139687 ENSG00000078674 ENSG00000166803 ENSG00000137055 ENSG00000176619 PMC5915062__F3 Proteomic alterations in early stage cervical cancer ENSG00000047410 ENSG00000105835 ENSG00000124789 ENSG00000102900 ENSG00000108055 ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000177963 ENSG00000198554 ENSG00000277263 ENSG00000110713 ENSG00000215301 ENSG00000137055 PMC7891830__F2 Golgi resident proteins and membrane trafficking pathway ENSG00000017260 ENSG00000102302 ENSG00000143375 PMC9279440__F5 Investigation on the cellular mechanism of Prunetin evidenced through next generation sequencing and bioinformatic approaches against gastric cancer ENSG00000188486 ENSG00000083799 ENSG00000168040 ENSG00000164342 PMC5935095__F3 Cooperative Instruction of Signaling and Metabolic Pathways on the Epigenetic Landscape ENSG00000198793 ENSG00000099810 PMC4377623__F2 Identification of proteins responsible for adriamycin resistance in breast cancer cells using proteomics analysis ENSG00000002549 PMC9020266__F1 Recent Advances in the Development of Non-PIKKs Targeting Small Molecule Inhibitors of DNA Double-Strand Break Repair ENSG00000149311 ENSG00000012048 ENSG00000083093 ENSG00000039650 ENSG00000197299 ENSG00000051180 ENSG00000310560 ENSG00000139618 PMC6538740__F1 Gegen Qinlian decoction enhances the effect of PD-1 blockade in colorectal cancer with microsatellite stability by remodelling the gut microbiota and the tumour microenvironment ENSG00000143799 ENSG00000291971 ENSG00000105401 ENSG00000198793 ENSG00000165280 ENSG00000170606 ENSG00000168036 ENSG00000183765 ENSG00000175054 ENSG00000134086 ENSG00000150991 ENSG00000066044 ENSG00000128052 ENSG00000136997 ENSG00000139687 ENSG00000140464 ENSG00000253729 ENSG00000103266 ENSG00000142192 ENSG00000005339 ENSG00000165119 ENSG00000100906 ENSG00000175793 ENSG00000131747 ENSG00000173039 ENSG00000213341 ENSG00000105568 ENSG00000168610 ENSG00000127445 ENSG00000065978 ENSG00000141480 ENSG00000096717 ENSG00000146648 ENSG00000127948 PMC7407977__F9 Molecular signal pathway of the proposed cell death crosstalk in B16 cells exposed to plasma induced-ROS ENSG00000168040 ENSG00000057663 PMC8378592__F2 Prediction and analysis of microRNAs involved in COVID-19 inflammatory processes associated with the NF-kB and JAK/STAT signaling pathways ENSG00000213928 ENSG00000111537 ENSG00000130234 ENSG00000108342 ENSG00000154016 PMC9662279__F5 SIRT6 in Aging, Metabolism, Inflammation and Cardiovascular Diseases ENSG00000145604 ENSG00000188786 ENSG00000105835 ENSG00000173039 ENSG00000077463 PMC8378592__F3 Prediction and analysis of microRNAs involved in COVID-19 inflammatory processes associated with the NF-kB and JAK/STAT signaling pathways ENSG00000150455 ENSG00000127191 ENSG00000010671 ENSG00000095585 ENSG00000149311 ENSG00000226275 ENSG00000213658 ENSG00000135960 ENSG00000170458 ENSG00000186716 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000162692 ENSG00000121060 PMC3145778__F9 Redox-Induced Src Kinase and Caveolin-1 Signaling in TGFB1-Initiated SMAD2/3 Activation and PAI-1 Expression ENSG00000163914 ENSG00000146648 PMC9662279__F7 SIRT6 in Aging, Metabolism, Inflammation and Cardiovascular Diseases ENSG00000285109 ENSG00000198793 ENSG00000185591 ENSG00000162924 ENSG00000077463 ENSG00000145782 ENSG00000251493 PMC7201075__F1 Arachidonate-prostanoids pathway gene expression in colorectal cancer (CRC) tumors ENSG00000122420 ENSG00000050628 ENSG00000160013 ENSG00000125384 ENSG00000168229 ENSG00000095303 ENSG00000148344 ENSG00000164120 ENSG00000124212 ENSG00000073756 ENSG00000160951 PMC4325920__F1 Roles of FMRP in the pathogenesis of AD ENSG00000142192 ENSG00000149269 ENSG00000010810 ENSG00000197283 ENSG00000198793 ENSG00000198576 ENSG00000196712 PMC3536146__F8 Pathway representation of canonical and Pyk2-mediated TLR9 signaling ENSG00000183735 ENSG00000169291 ENSG00000239732 ENSG00000177606 ENSG00000134070 ENSG00000172936 ENSG00000131323 ENSG00000168040 ENSG00000175104 PMC10526250__F1 Changes in the Acetylcholinesterase Enzymatic Activity in Tumor Development and Progression ENSG00000002330 PMC3322338__F1 Hypothetical model for neuroimmune-related actions of miRNAs in brain of human alcoholics (e.g., in microglia) ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 ENSG00000121966 PMC5187688__F5 TCA pathway ENSG00000082212 ENSG00000062485 PMC5379509__F8 Novel one-class SVM based negative data sampling method for reconstructing proteome-wide HTLV-human protein interaction networks ENSG00000105672 ENSG00000173039 ENSG00000092847 ENSG00000285152 ENSG00000043462 ENSG00000275122 ENSG00000091073 ENSG00000065717 ENSG00000101882 ENSG00000150991 ENSG00000213658 ENSG00000065526 ENSG00000101849 ENSG00000100387 ENSG00000078747 ENSG00000205155 ENSG00000015285 ENSG00000188095 ENSG00000105810 ENSG00000102935 ENSG00000101752 ENSG00000100603 PMC5712622__F3 Akt/mTOR pathway represents a major axis of phosphorylation signal transduction in response to phagocytosis ENSG00000002330 ENSG00000198793 ENSG00000169047 ENSG00000136997 ENSG00000204673 ENSG00000168036 ENSG00000164327 ENSG00000141564 ENSG00000171791 ENSG00000124253 ENSG00000069966 PMC3474235__F1 The prostaglandin biosynthetic pathway (adapted from ) 15-deoxyΔ12-14-PGJ2 is a metabolite derived from arachidonic acid PMC4900217__F2 Induction of oxidative stress and defense pathways ENSG00000183463 ENSG00000086991 ENSG00000007171 ENSG00000158125 PMC7782450__F3 Amino acid catabolism caused by ARG1 and IDO triggers a shortage of l-arginine and tryptophan, disturbing the homeostasis of host tissues ENSG00000128272 ENSG00000144895 ENSG00000198793 ENSG00000118520 PMC3474235__F2 Scheme of the various interactions between GSTs and MAPK implicated in stress-signaling pathway (adapted from ) ENSG00000170899 ENSG00000127191 PMC4900217__F6 Metabolic reprogramming for NADPH production ENSG00000180210 ENSG00000171174 ENSG00000197713 ENSG00000158104 ENSG00000153574 ENSG00000146733 PMC5564037__F4 Capturing Human Naïve Pluripotency in the Embryo and in the Dish ENSG00000187569 ENSG00000204335 ENSG00000162337 ENSG00000134982 ENSG00000135111 ENSG00000127528 ENSG00000168036 ENSG00000168610 ENSG00000136826 ENSG00000008083 ENSG00000276043 ENSG00000071564 ENSG00000142182 ENSG00000138336 ENSG00000115112 ENSG00000128342 PMC8914318__F7 New Vistas in microRNA Regulatory Interactome in Neuropathic Pain ENSG00000162711 ENSG00000138166 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000265972 ENSG00000150455 ENSG00000175104 ENSG00000127191 ENSG00000184216 ENSG00000121966 PMC7961479__F1 Predominant signaling pathways contributing to melanomagenesis and progression ENSG00000198793 PMC6801787__F1 Schematic illustration vitamin D synthesis pathway and signalling mechanisms relevant to PAD formation ENSG00000111012 ENSG00000205221 ENSG00000105516 ENSG00000135929 PMC7961479__F2 Activating mutations and activation of alternative upstream receptors confer resistance to inhibitors targeting aberrant MAPK signaling ENSG00000157764 ENSG00000198793 PMC8619854__F3 Promising Role of TGFB Pathway in Response to Regorafenib in Metastatic Colorectal Cancer: A Case Report ENSG00000010810 ENSG00000026103 PMC9397497__F6 Electrical stimulated GLUT4 signalling attenuates critical illness‐associated muscle wasting ENSG00000198793 ENSG00000136111 PMC3370605__F1 Roles of N-acetyl-l-glutamate synthase (NAGS) and of its homologous enzyme N-acetyl-l-glutamate kinase (NAGK) in arginine biosynthesis ENSG00000124357 ENSG00000118520 ENSG00000036473 PMC6691238__F1 Cell apoptosis under ER stress ENSG00000128272 ENSG00000144895 ENSG00000171791 ENSG00000127191 PMC3078503__F4 PIKKs and TCR-associated pathways ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 PMC4662426__F5 Difference in expression of the calcium signaling pathway between rat neurons and OPCs grown in vitro ENSG00000182533 ENSG00000156026 ENSG00000186716 PMC12075545__F6 IFN-Gamma-mediated suppression of ANGPT2-Tie2 in endothelial cells facilitates tumor vascular normalization during immunotherapy ENSG00000115415 ENSG00000150907 ENSG00000091879 PMC4438385__F1 Brown adipose tissue uncoupling and thermogenesis ENSG00000042832 PMC4332855__F3 Mycobiota: interactions between commensal fungi and the host immune system ENSG00000096996 ENSG00000187796 ENSG00000172243 ENSG00000115415 ENSG00000163220 ENSG00000125538 ENSG00000168610 PMC9774157__F6 Maqui Berry and Ginseng Extracts Reduce Cigarette Smoke-Induced Cell Injury in a 3D Bone Co-Culture Model ENSG00000100985 ENSG00000131196 ENSG00000079999 PMC4919473__F7 Inhibition of LINE-1 retrotransposition by the SLX4com prevents pro-inflammatory signaling ENSG00000154920 ENSG00000188827 PMC6204284__F2 An illustration of spontaneous DNA double strand break induction and their roles in maintaining the stemness and tumorigenicity of cancer cells ENSG00000149311 ENSG00000168610 ENSG00000164305 ENSG00000084774 PMC11881714__F2 Normal copper metabolism ENSG00000173992 ENSG00000138495 ENSG00000123191 ENSG00000166260 ENSG00000177556 PMC11881714__F3 Mechanisms of neuronal damage attributable to Cu toxicity ENSG00000142192 PMC12095056__F4 Cilia and ciliary signaling contribute to therapeutic resistance ENSG00000149311 ENSG00000175054 ENSG00000171791 ENSG00000118777 PMC4868425__F8 The GLUD2 genotype effect on mouse metabolome ENSG00000005339 PMC6148547__F6 MiR-106p-5p in cervical cancer: from expression to molecular mechanism ENSG00000105664 ENSG00000198793 ENSG00000150093 ENSG00000112715 PMC7376809__F1 An update on stem cell therapy for Asherman syndrome ENSG00000134982 ENSG00000168036 PMC5104320__F4 MinePath: Mining for Phenotype Differential Sub-paths in Molecular Pathways ENSG00000117020 ENSG00000065361 ENSG00000113070 ENSG00000198793 ENSG00000158458 ENSG00000146648 ENSG00000187840 PMC4579870__F2 Core UPR pathway and its modulation on autophagy ENSG00000177169 ENSG00000128272 ENSG00000083290 ENSG00000144895 ENSG00000150907 ENSG00000127191 ENSG00000057663 PMC4579870__F1 Molecular events in autophagy pathway ENSG00000152348 ENSG00000198382 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC5807095__F9 Signaling events that are induced by the LH surge and regulate the processes of ovulation and luteinization ENSG00000122420 ENSG00000004399 ENSG00000171388 ENSG00000113494 PMC5807095__F3 Hedgehog signaling pathway components in the ovary ENSG00000164404 ENSG00000106571 ENSG00000117425 ENSG00000164161 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC4548949__F3 Transcriptome Profiling and Molecular Pathway Analysis of Genes in Association with Salinity Adaptation in Nile Tilapia Oreochromis niloticus ENSG00000131473 ENSG00000101670 ENSG00000081181 ENSG00000143549 ENSG00000198336 ENSG00000149091 ENSG00000169710 ENSG00000115350 ENSG00000100033 ENSG00000129187 ENSG00000173868 ENSG00000062282 ENSG00000137801 ENSG00000189283 ENSG00000041982 ENSG00000115850 ENSG00000186340 ENSG00000177606 ENSG00000036473 ENSG00000119125 PMC4548949__F4 Transcriptome Profiling and Molecular Pathway Analysis of Genes in Association with Salinity Adaptation in Nile Tilapia Oreochromis niloticus ENSG00000101670 ENSG00000087245 ENSG00000197838 ENSG00000174915 ENSG00000169047 ENSG00000173868 ENSG00000241878 ENSG00000137801 ENSG00000067606 ENSG00000177606 ENSG00000155660 ENSG00000159399 ENSG00000140443 PMC4846903__F5 ErbB4 signal pathway ENSG00000124102 ENSG00000065361 ENSG00000138798 ENSG00000115904 ENSG00000131095 ENSG00000160691 ENSG00000123124 ENSG00000122882 ENSG00000069869 ENSG00000082175 ENSG00000078747 ENSG00000146648 ENSG00000178568 PMC3784453__F10 Leu452His Mutation in Lipoprotein Lipase Gene Transfer Associated with Hypertriglyceridemia in Mice in vivo ENSG00000042832 ENSG00000096088 ENSG00000175567 ENSG00000096717 PMC11068999__F4 Hh signaling pathway ENSG00000134982 ENSG00000168036 ENSG00000139687 PMC9268899__F1 Astrocytes in Neurodegeneration: Inspiration From Genetics ENSG00000198793 ENSG00000100985 PMC11068999__F2 Wnt/Beta-catenin pathway ENSG00000134982 ENSG00000168036 ENSG00000139687 PMC11670693__F1 Inhibition of the canonical Wnt/Beta-catenin signaling pathway by BI 905681 ENSG00000281324 ENSG00000162337 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000196628 PMC7961479__F3 MAPK, PI3K, and angiogenic reactivation confers resistance to c-KIT and VEGFR TKIs ENSG00000198793 PMC9581055__F10 Identification of Biomarkers Controlling Cell Fate In Blood Cell Development ENSG00000151702 ENSG00000157554 ENSG00000137834 ENSG00000152661 ENSG00000129757 ENSG00000125398 ENSG00000177606 ENSG00000168036 ENSG00000107485 ENSG00000185591 ENSG00000131196 PMC7664111__F7 Graphical rendering of GRP78-dependent CRIPTO signaling driving stem-like tumor cell phenotypes ENSG00000291971 ENSG00000241186 ENSG00000156574 PMC12035885__F2 Crucial environmental factors associated with NK cell function in the TME of breast cancer ENSG00000134460 ENSG00000111537 ENSG00000168610 PMC12035885__F3 Main metabolites in the TME of breast cancer that affect NK cell function ENSG00000111537 ENSG00000167996 ENSG00000276051 ENSG00000231179 ENSG00000204520 PMC4557010__F7 Schematic models for JAK/STAT cell signaling pathway and the inhibitory actions for JAK/STAT target anticancer drugs ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000128342 PMC6855049__F6 Antifracture pathways of potential targets for treating fracture from main active ingredients of Drynariae Rhizoma ENSG00000142192 ENSG00000070831 ENSG00000291971 ENSG00000130522 ENSG00000136997 ENSG00000175104 PMC5069086__F6 Schematic model for HCV-induced CD4+ T cell senescence regulated by the ΔNp63–miR-181a–Sirt1 and ΔNp63–miR181a–DUSP6 signaling pathways ENSG00000049768 ENSG00000096717 PMC4939511__F2 Signal pathways of migration inhibitory factor (MIF) ENSG00000019582 ENSG00000177606 ENSG00000026508 PMC10149936__F14 Cofilin activation in pancreatic acinar cells plays a pivotal convergent role for mediating CCK-stimulated enzyme secretion and growth ENSG00000291971 ENSG00000163914 ENSG00000130669 PMC7015662__F1 AIM2 inflammasome activation ENSG00000154451 ENSG00000278718 ENSG00000213928 ENSG00000163568 ENSG00000140451 PMC7120363__F2 Autophagy is involved in the regulation of the normal function of the intestinal mucosa and the pathogenesis of enteritis ENSG00000237693 ENSG00000100219 ENSG00000057663 PMC3192861__F10 A schematic model of GC-mediated acute activation of NHE3 via SGK3 ENSG00000101049 ENSG00000288269 ENSG00000118515 ENSG00000145321 PMC7301251__F3 Study on the Drug Targets and Molecular Mechanisms of Rhizoma Curcumae in the Treatment of Nasopharyngeal Carcinoma Based on Network Pharmacology ENSG00000114200 ENSG00000087245 ENSG00000157764 ENSG00000134982 ENSG00000198793 ENSG00000087085 ENSG00000171791 ENSG00000112715 ENSG00000118777 ENSG00000171345 ENSG00000277571 ENSG00000134086 ENSG00000082175 ENSG00000157227 ENSG00000177606 ENSG00000136997 ENSG00000164362 ENSG00000146648 ENSG00000227345 PMC9528770__F2 Brain–immune interaction mechanisms: Implications for cognitive dysfunction in psychiatric disorders ENSG00000102871 ENSG00000198793 ENSG00000168040 ENSG00000127191 PMC12045570__F2 Ferroptosis related signaling pathway affected by EBV, HTLV-I and KSHV viruses ENSG00000138449 ENSG00000151012 ENSG00000197635 ENSG00000162772 ENSG00000142082 ENSG00000102967 ENSG00000124762 ENSG00000168003 ENSG00000175536 ENSG00000144554 ENSG00000066044 ENSG00000167468 ENSG00000127948 PMC4862632__F1 Head-to-Head Comparison of Anti-Inflammatory Performance of Known Natural Products In Vitro ENSG00000102871 ENSG00000138798 ENSG00000173039 ENSG00000172936 ENSG00000136869 ENSG00000100985 ENSG00000127191 ENSG00000168610 ENSG00000146648 ENSG00000064012 ENSG00000164305 ENSG00000132693 PMC8881509__F7 Extracellular circulating miRNAs as stress-related signature to search and rescue dogs ENSG00000149311 ENSG00000175054 ENSG00000136997 ENSG00000112378 PMC7271281__F4 The ncRNA pivot regulator on the dysfunction module ENSG00000099812 PMC2897923__F1 Striking the Target in Wnt-y Conditions: Intervening in Wnt Signaling During Cancer Progression ENSG00000134982 ENSG00000196628 ENSG00000105723 PMC6721308__F2 Distribution of the genes significantly modulated in the Alzheimer’s disease pathway ENSG00000142192 ENSG00000143801 ENSG00000115310 ENSG00000120868 PMC2897923__F2 Striking the Target in Wnt-y Conditions: Intervening in Wnt Signaling During Cancer Progression ENSG00000164932 PMC9380335__F6 Impact of fetal exposure to mycotoxins on longissimus muscle fiber hypertrophy and miRNA profile ENSG00000177455 ENSG00000103479 ENSG00000065833 ENSG00000002330 ENSG00000186716 ENSG00000104894 PMC2897923__F3 Striking the Target in Wnt-y Conditions: Intervening in Wnt Signaling During Cancer Progression ENSG00000169071 ENSG00000026508 ENSG00000170498 ENSG00000168610 PMC3205325__F2 Canonical TGFB signaling; Smad-dependent pathway downstream of TGFB receptors PMC4047858__F7 Combined metabolomics–transcriptomics identification of pathways affected by MPP+ ENSG00000228716 ENSG00000065911 ENSG00000092621 ENSG00000135069 ENSG00000047936 ENSG00000146733 ENSG00000116761 PMC3477860__F4 Schematic diagrams of the role of STAT1 in antimycobacterial, antiviral and antifungal immunity ENSG00000213928 ENSG00000187796 ENSG00000140968 ENSG00000103522 ENSG00000125347 ENSG00000168610 ENSG00000163702 ENSG00000162594 ENSG00000096996 ENSG00000105397 ENSG00000115415 ENSG00000131323 ENSG00000164342 PMC7252450__F4 Advances in circular RNAs and their role in glioma (Review) ENSG00000124102 ENSG00000104967 ENSG00000124766 ENSG00000000971 ENSG00000168036 ENSG00000168610 ENSG00000136231 ENSG00000260027 ENSG00000135446 ENSG00000123374 ENSG00000100985 ENSG00000155760 ENSG00000146648 PMC6519821__F7 Proposed molecular mechanism of the anti-esophageal cancer activity of Rk3 ENSG00000132906 ENSG00000002330 ENSG00000135446 ENSG00000198793 ENSG00000164305 ENSG00000057663 PMC7461358__F10 MiR-199a-3p and miR-199a-5p might affect MAPK signaling pathway by regulating DUSP5 and MAP3K11 ENSG00000121989 ENSG00000197702 ENSG00000104368 PMC5137819__F1 Phosphatidylinositol‐3 kinase (PI3K)–AKT PI3K‐AKT pathway is activated upstream by ligand binding to a growth factor receptor, in this case a receptor tyrosine kinase (RTK) ENSG00000002330 ENSG00000005882 ENSG00000150907 ENSG00000198793 ENSG00000184481 PMC8250149__F2 NLRC5: A Potential Target for Central Nervous System Disorders ENSG00000226275 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000121060 ENSG00000123268 PMC6820523__F9 Our proposed model of nsDNA-induced APOL1 expression through engagement of the cGAS/IFI16-STING pathway in human immortalized AB8/13 podocytes ENSG00000183735 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000163565 PMC4031758__F2 Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9333241__F8 Mapping of gene expression change on Na/K-ATPase/Src signaling pathway ENSG00000179091 ENSG00000167941 ENSG00000148082 ENSG00000010810 ENSG00000111837 ENSG00000116096 PMC9465375__F4 Roxadustat: Not just for anemia ENSG00000171791 PMC6324838__F1 Overview schematic of the proposed relationship of inhalant organic dust exposures induction of bone loss ENSG00000167207 ENSG00000163739 ENSG00000172936 ENSG00000136869 PMC6770051__F5 miRNA-responsive biological pathways and the presence or absence of interactions between its genes and the transfected miRNA ENSG00000008710 ENSG00000159224 ENSG00000128512 ENSG00000070831 ENSG00000135413 ENSG00000184787 ENSG00000198168 ENSG00000135506 ENSG00000291983 ENSG00000150991 ENSG00000169220 ENSG00000213658 ENSG00000144895 ENSG00000100387 ENSG00000163914 ENSG00000113558 ENSG00000160293 ENSG00000125968 ENSG00000084774 PMC2663984__F5 Expanded canonical Wnt/GSK3 signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5263152__F1 Canonical and non-canonical NLRP3 inflammasome activation ENSG00000162711 ENSG00000189403 ENSG00000136869 PMC12210545__F3 Complement system and the role of HCQ ENSG00000166278 PMC8250149__F3 NLRC5: A Potential Target for Central Nervous System Disorders ENSG00000168036 ENSG00000112715 PMC3031501__F8 Ablation of Akt2 Induces Autophagy through Cell Cycle Arrest, the Downregulation of p70S6K, and the Deregulation of Mitochondria in MDA-MB231 Cells ENSG00000145604 ENSG00000198793 ENSG00000123374 PMC4820338__F1 Schematic model of RIP1-mediated regulation of the PI3K-Akt pathway ENSG00000169047 ENSG00000198793 PMC5034700__F1 Proposed metabolic pathway of lapatinib PMC9169033__F4 Metabolic adaptations in MS ENSG00000115419 ENSG00000026103 PMC7791185__F9 NLRP3 Inflammasome Activation and Pyroptosis in Lactate‐stimulated Human NP Cells ENSG00000278718 ENSG00000162711 PMC8326261__F3 Genetic variant of cyclooxygenase-2 in gastric cancer: More inflammation and susceptibility ENSG00000239732 ENSG00000163739 ENSG00000172936 ENSG00000105698 PMC5520506__F1 PI3K/Akt signalling and its activation in cancer ENSG00000117020 PMC7849620__F4 Mechanisms of abnormal coagulation and hepatic ischemia/hypoxia reperfusion injury in COVID-19-associated liver injury ENSG00000169245 ENSG00000108691 ENSG00000110799 ENSG00000125538 ENSG00000169429 ENSG00000136869 ENSG00000121807 PMC3355838__F3 Wnt signaling pathways ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000132478 PMC3355838__F1 Step model of thyroid carcinogenesis ENSG00000157764 ENSG00000168036 ENSG00000165409 PMC3355838__F2 Genetic events involved in thyroid tumor initiation and progression ENSG00000157764 ENSG00000165409 PMC12154509__F4 SIRS signaling: inflammatory pathways during shock and cytokine storm and the production of soluble cytokine receptor antagonists ENSG00000172936 ENSG00000175104 PMC10969160__F1 Summary of potential therapeutic targets ENSG00000168283 ENSG00000281324 ENSG00000137673 ENSG00000106004 ENSG00000162337 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000026508 ENSG00000168036 ENSG00000128602 PMC11866803__F10 Hsa_circ_0125356 promotes gemcitabine resistance by modulating WNT canonical and non-canonical pathways via miR-582-5p/FGF9 axis in non-small cell lung cancer ENSG00000100592 ENSG00000168036 ENSG00000102678 ENSG00000123908 PMC12192441__F1 Signaling pathways of activins and other TGFB related ligands in adipocytes ENSG00000121989 ENSG00000170365 ENSG00000184344 ENSG00000204217 ENSG00000114739 PMC6580686__F1 miRNAs regulating the conserved pathways of aging in skeletal muscle ENSG00000164362 ENSG00000096717 PMC4454460__F5 A model showing different pathways to repair replication fork damage due to structure-forming sequences ENSG00000051180 PMC4436567__F2 Effectors interfering with SA-dependent signaling and gene regulation ENSG00000156603 PMC7398379__F5 Proposed model of the transgelin mechanisms involved in promoting colon cancer metastasis ENSG00000143799 ENSG00000163914 ENSG00000015285 ENSG00000143933 ENSG00000213672 PMC6321180__F3 Wnt1/Beta-catenin signaling as a key player in glia–neuron cross-talk ENSG00000125084 PMC6321180__F1 Canonical Wingless-type mouse mammary tumor virus (MMTV) integration site (Wnt) pathway and non-canonical Wnt/Ca2+ and Wnt/planar cell polarity (PCP) pathways [,,,,,] ENSG00000169071 ENSG00000162337 ENSG00000070831 ENSG00000134982 PMC6321180__F2 Wnt1/Beta-catenin signaling regulation of midbrain dopaminergic (mDAergic) neuron survival/death according to our published findings [,,,,,,,,] ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC7530130__F28 Enzymatic Noncovalent Synthesis ENSG00000137275 ENSG00000168404 PMC7904711__F1 Shh pathway ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC10150162__F9 Progress in non-viral localized delivery of siRNA therapeutics for pulmonary diseases ENSG00000108691 ENSG00000006451 ENSG00000121807 PMC9121315__F9 Hepatic pannexin‐1 mediates ST2+ regulatory T cells promoting resolution of inflammation in lipopolysaccharide‐induced endotoxemia ENSG00000162711 ENSG00000137033 ENSG00000136869 ENSG00000110218 PMC5732537__F8 Virus-induced endoplasmic reticulum (ER) stress and the consequent downregulation of the stimulator of interferon genes (STING) pathway in acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) ENSG00000183735 ENSG00000164430 PMC9037064__F3 Progress in the Study of Non-Coding RNAs in Multidifferentiation Potential of Dental-Derived Mesenchymal Stem Cells ENSG00000083857 ENSG00000095739 ENSG00000115415 ENSG00000168036 ENSG00000168610 ENSG00000196628 PMC4233036__F2 Pathway analysis highlights opposing regulation of a DNA repair pathway in radioresistant versus radiosensitive cells ENSG00000149311 ENSG00000175054 ENSG00000111537 PMC6610339__F1 Release of mitochondrial proteins and mtDNA initiates an inflammatory response in CICD ENSG00000162711 ENSG00000239732 ENSG00000164430 PMC9039039__F7 Research Progress of Exosomes in Bone Diseases: Mechanism, Diagnosis and Therapy ENSG00000141232 ENSG00000110395 ENSG00000126838 PMC2830572__F1 TNF A inhibits erythropoiesis by direct and indirect effects ENSG00000187266 ENSG00000179348 PMC2811741__F7 Mast Cells Mobilize Myeloid-Derived Suppressor Cells and Treg Cells in Tumor Microenvironment via IL-17 Pathway in Murine Hepatocarcinoma Model ENSG00000102962 ENSG00000108691 ENSG00000100985 PMC7764352__F7 STRING: AML associated enriched pathways among the top 94 identified drug targets ENSG00000168028 ENSG00000167941 ENSG00000072274 ENSG00000177084 PMC7840718__F3 Wnt growth factor triggers macropinocytosis by binding to co-receptors Frizzled (Fz) and LDL receptor-related protein 6 (Lrp6) on the cell surface ENSG00000281324 ENSG00000134982 ENSG00000149269 ENSG00000126457 ENSG00000168036 PMC11118937__F1 Nrf2 signaling in mitigating heat stress and xenobiotic-induced oxidative distress and apoptosis ENSG00000079999 PMC8751739__F8 Suppressive effects of dental pulp stem cells and its conditioned medium on development and migration of colorectal cancer cells through MAPKinase pathways ENSG00000168036 ENSG00000171791 ENSG00000026103 PMC7644630__F2 TBK1 and Innate Immune Signaling ENSG00000183735 ENSG00000164430 ENSG00000123240 ENSG00000088888 ENSG00000137275 ENSG00000173039 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC7840718__F1 Cancer cells ingesting extracellular small particles, such as protein, necrotic debris, and ATP, through macropinocytosis ENSG00000070831 ENSG00000149269 ENSG00000198793 ENSG00000146648 PMC7840718__F2 Growth factors stimulation induces the PI3K/Akt/mTORC1 pathway PMC4400645__F1 PI3K Pathway Balances Self-Renewal and Differentiation of Nephron Progenitor Cells through Beta-Catenin Signaling ENSG00000168036 ENSG00000276799 PMC6008200__F7 Comparative transcriptome profiling of the human and mouse dorsal root ganglia: an RNA-seq-based resource for pain and sensory neuroscience research ENSG00000162889 ENSG00000140992 ENSG00000002330 ENSG00000282905 ENSG00000100906 ENSG00000070831 ENSG00000095015 ENSG00000178363 ENSG00000169885 ENSG00000166484 ENSG00000099942 ENSG00000160999 ENSG00000137764 ENSG00000171606 ENSG00000129007 ENSG00000185652 ENSG00000128272 ENSG00000143801 ENSG00000197943 ENSG00000134243 ENSG00000124181 ENSG00000175104 PMC2858667__F1 Endocannabinoids Differentially Modulate Synaptic Plasticity in Rat Hippocampal CA1 Pyramidal Neurons ENSG00000164879 ENSG00000166278 PMC8192250__F1 Mechanisms linking gut microbial metabolites to insulin resistance ENSG00000142611 ENSG00000169047 ENSG00000124253 ENSG00000196689 PMC9362167__F4 Ursolic acid and SARS-CoV-2 infection: a new horizon and perspective ENSG00000162711 ENSG00000198793 ENSG00000168610 PMC3138544__F1 Targets and therapies for B-cell non-Hodgkin's lymphoma (B-NHL) within the context of the 10 hallmarks of cancer and overlapping oncogenic signaling pathways ENSG00000198793 ENSG00000010671 PMC9248984__F3 Targets for limiting DC maturation / activation ENSG00000118515 ENSG00000126353 PMC4254517__F2 Anti- and pro-apoptotic roles of RIPK1(A) Upon TNFR-1 ligation ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000064012 ENSG00000285379 PMC7069528__F1 Effect of cannabidiol (CBD) in Parkinson's disease and Alzheimer' disease (AD) ENSG00000142192 ENSG00000117480 ENSG00000125538 ENSG00000131095 ENSG00000196689 PMC3295030__F1 Simplified description of the insulin/IGF-1 signal transduction (IIS) pathway in invertebrates and mammals ENSG00000117020 ENSG00000169047 ENSG00000133124 ENSG00000281518 ENSG00000184481 PMC2896944__F3 Hsp90 shelters aberrant neuronal proteins ENSG00000158828 PMC5709276__F1 Pathway alterations in glioblastoma multiforme ENSG00000157764 ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000146648 ENSG00000196712 ENSG00000198625 PMC10860821__F3 OA is a condition that involves the breakdown of cartilage in the joints ENSG00000162711 ENSG00000154736 ENSG00000125538 PMC10860821__F1 Three types of pyroptosis pathway ENSG00000278718 ENSG00000162711 ENSG00000137275 ENSG00000134326 ENSG00000172936 ENSG00000136869 PMC5836578__F5 Bioinformatic analysis of ATP-binding cassette subfamily A member 1 (ABCA1), revealing its preventive role in carotid plaque rupture and atherosclerosis progression during the inflammatory reaction ENSG00000084676 ENSG00000101849 PMC7290603__F3 Impact of tumor-derived EVs in Cancer Therapy Resistance ENSG00000164938 ENSG00000168036 PMC123677__F3 The action of S-phase checkpoints in the suppression of spontaneous genome instability ENSG00000157856 ENSG00000132646 ENSG00000163918 ENSG00000133119 PMC4553792__F3 Inactivation of DPH5 induces NFKB and death receptor pathways ENSG00000104365 ENSG00000005339 ENSG00000100906 ENSG00000109320 ENSG00000138798 ENSG00000173039 ENSG00000125347 ENSG00000168610 ENSG00000111537 ENSG00000115415 ENSG00000177606 ENSG00000125538 ENSG00000185591 PMC6478864__F1 Wee1 inactivates Cdk1 by phosphorylation at tyrosine 15 ENSG00000134057 ENSG00000171848 PMC7064006__F13 Possible metabolic pathway maps associated with the lipid biomarkers in dampness-heat induced diarrhea and dampness-heat induced diarrhea with PD treatment ENSG00000223802 ENSG00000173599 ENSG00000198670 ENSG00000184207 PMC7503462__F1 Schematic description of tryptophan metabolic pathways with assigned physiological roles and regulatory points of select metabolites ENSG00000125538 ENSG00000188676 PMC8924449__F9 Transcriptomic and Metabolomic Analyses Reveal Key Metabolites, Pathways and Candidate Genes in Sophora davidii (Franch.) Skeels Seedlings Under Drought Stress ENSG00000163435 ENSG00000158104 ENSG00000169032 ENSG00000100033 ENSG00000131188 ENSG00000158125 PMC3557440__F4 Schematic overview of the homologous recombination (HR) pathway ENSG00000051180 PMC9169637__F7 Monocyte-derived SDF1 supports optic nerve regeneration and alters retinal ganglion cells’ response to Pten deletion ENSG00000122543 ENSG00000198793 ENSG00000121966 PMC11430608__F1 Mechanism of development of AP ENSG00000168610 PMC7353012__F3 Functions of UCA1, lincRNA-ROR, and lncRNA MIR2052HG in the tamoxifen resistance of breast cancer ENSG00000142235 ENSG00000198793 ENSG00000168036 ENSG00000164086 PMC12000292__F4 ANXA2 inhibits tumour cell apoptosis and its effects on tumour immunity ENSG00000182718 ENSG00000177169 ENSG00000162711 ENSG00000168040 ENSG00000026103 PMC7353012__F4 Functions of GAS5, DSCAM-AS1, and Eleanors in the tamoxifen resistance of breast cancer PMC4069315__F1 Mechanisms of action of lactic acid bacteria via extrinsic and intrinsic pathways of apoptosis ENSG00000026103 PMC3384717__F9 Androgens up-regulating PCa cell proliferation via p66Shc-ROS signal pathway PMC4069315__F2 Immune responses induced by lactic acid bacteria ENSG00000226275 PMC6893972__F7 Neuronal molecular pathways indicate glutamate and dopamine receptor signaling, in a representation of 45-day cerebral organoid proteomes ENSG00000115419 PMC7747855__F7 Astrocytic SHH signaling pathway regulates BBB integrity after ICH ENSG00000164690 ENSG00000128602 PMC7356355__F1 Intoxification Pathway ENSG00000138798 PMC8844822__F1 SARM1 is a multi-functional NAD(P)ase with prominent base exchange activity, all regulated bymultiple physiologically relevant NAD metabolites ENSG00000105835 ENSG00000157064 PMC9446157__F2 Calcium signaling in cancer metastasis to bone ENSG00000187688 ENSG00000092439 ENSG00000144935 ENSG00000167323 ENSG00000291971 ENSG00000165125 ENSG00000146678 ENSG00000140443 PMC8127498__F8 Tissue-specific transcriptome analyses reveal candidate genes for stilbene, flavonoid and anthraquinone biosynthesis in the medicinal plant Polygonum cuspidatum ENSG00000110921 ENSG00000167508 PMC6001756__F1 Estrogen receptor (ER) signalling pathway ENSG00000291971 ENSG00000136997 ENSG00000185591 ENSG00000146648 PMC12000292__F2 ANXA2-induced autophagy inhibits apoptosis in tumour cells ENSG00000182718 ENSG00000197747 ENSG00000177169 ENSG00000112561 ENSG00000168610 PMC3310197__F7 Interactions of signaling by ER stress, oxidative stress, and cytokines with the pathways of autophagy: Induction of autophagy requires the assembly of Beclin-1 with class III PI 3 kinase (Vps34) and UVRAG ENSG00000152348 ENSG00000198382 ENSG00000198793 ENSG00000144848 ENSG00000145782 PMC4826689__F1 Canonical Wnt signaling pathway (Beta-catenin-dependent Wnt signaling pathway) ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4826689__F2 Noncanonical Wnt signaling pathway (Beta-catenin-independent Wnt signaling pathway) ENSG00000087095 ENSG00000134982 ENSG00000168036 PMC4613338__F1 Glutamine metabolism and potent targets for cancer therapy ENSG00000151012 ENSG00000198793 ENSG00000136997 ENSG00000103257 PMC5402045__F2 ST2/IL-33 signaling pathway ENSG00000239732 ENSG00000137033 ENSG00000107485 ENSG00000172936 ENSG00000049768 ENSG00000125347 ENSG00000175104 ENSG00000184216 PMC9107211__F3 Incidence and immunomic features of apyretic COVID-19 in patients affected by solid tumors: a prospective cohort study ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000145321 ENSG00000110651 ENSG00000152689 ENSG00000010671 PMC5927707__F2 Involvement of ZMYND8 and demethylases in the DDR and cancer ENSG00000065833 ENSG00000167491 ENSG00000073614 ENSG00000126012 PMC11813773__F2 Dual roles of SBAs in colon cells: anticancer and cancer-promoting effects ENSG00000146648 ENSG00000198625 PMC11813773__F3 Anticancer effects of SBAs in Hepatocellular Carcinoma (HCC) and Pancreatic Cancer ENSG00000168610 ENSG00000165795 PMC8152700__F5 Cardiac fibrosis ENSG00000281324 ENSG00000133110 ENSG00000162337 ENSG00000134982 ENSG00000291748 ENSG00000108821 PMC7352479__F3 Crosstalk among glycolysis, MAPK, and PI3K pathways ENSG00000002330 PMC7352479__F1 Glucose metabolism ENSG00000159399 PMC7352479__F2 Oxidative stress pathways ENSG00000178573 ENSG00000198793 ENSG00000079999 PMC3017081__F4 Cell cycle G1/S check point subnetwork ENSG00000105329 ENSG00000129355 ENSG00000149308 ENSG00000118707 ENSG00000147854 ENSG00000124762 ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000275214 ENSG00000118495 ENSG00000198176 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000139687 PMC5330121__F6 The interactive pathways of stress-responsive miRNAs and their targets ENSG00000001167 ENSG00000134548 PMC3017081__F3 Crosstalk between interleukin signalling pathways ENSG00000164399 ENSG00000113520 ENSG00000104432 ENSG00000113525 PMC6456508__F8 TLR4/NFKB pathway mediating miR-625-5p and COL1A1 in IDD pathogenesis ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000108821 ENSG00000010671 PMC11430608__F3 Activated intracellular signaling pathways in acute pancreatitis and their inhibition by natural compounds ENSG00000172936 ENSG00000136869 ENSG00000168404 ENSG00000168610 ENSG00000079999 PMC9505822__F1 Combined PARP and Dual Topoisomerase Inhibition Potentiates Genome Instability and Cell Death in Ovarian Cancer ENSG00000154059 ENSG00000042088 ENSG00000138385 PMC9599866__F3 Targeting KRAS in PDAC: A New Way to Cure It? ENSG00000198793 ENSG00000087586 ENSG00000146648 PMC4513356__F1 Wnt Signaling in Dendritic Cells: Its Role in Regulation of Immunity and Tolerance ENSG00000168036 ENSG00000049768 PMC7705326__F1 Mechanism of action of possible anti-SARS-CoV-2 drugs on the interferon signaling pathway ENSG00000213928 ENSG00000198793 ENSG00000125347 ENSG00000168610 ENSG00000276561 ENSG00000183735 ENSG00000138378 ENSG00000239732 ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000164342 PMC4163504__F1 Proposed molecular interaction between two neuropathologies such as major depressive disorder and Alzheimer’s disease ENSG00000164879 ENSG00000142192 PMC3085438__F5 Working model for the role of CCN6 in breast cancer invasion ENSG00000169047 ENSG00000140443 PMC7999260__F3 Combination therapy for miR-21i and TMZ ENSG00000171791 ENSG00000168610 PMC7999260__F4 General principle of the HSV-TK suicide gene system ENSG00000149311 ENSG00000168040 PMC7593559__F2 AAI can activate TGFB/Smad-independent signaling pathways to cause abnormal cell proliferation ENSG00000150782 ENSG00000140505 ENSG00000171791 ENSG00000140465 ENSG00000146648 PMC3757404__F1 Wnt/Beta-catenin Signaling Pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000168036 PMC3390257__F2 mTOR: from growth signal integration to cancer, diabetes and ageing ENSG00000100811 ENSG00000169047 ENSG00000285069 ENSG00000080546 PMC9338659__F4 Frontier progress of the combination of modern medicine and traditional Chinese medicine in the treatment of hepatocellular carcinoma ENSG00000138798 ENSG00000198793 ENSG00000168610 ENSG00000146648 ENSG00000057663 PMC11520425__F1 Classic Wnt/Beta-catenin signaling pathway: mechanisms in closed and open states ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11520425__F2 Wnt signalling regulation of osteoblasts and osteoclasts ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000171444 ENSG00000291971 ENSG00000163914 ENSG00000168036 ENSG00000160447 PMC11575928__F2 Survival mechanisms of ovarian cancer spheroids in ascites ENSG00000019991 ENSG00000122691 ENSG00000074181 ENSG00000134871 ENSG00000155760 PMC11575928__F3 TAMs in spheroid formation, survival and metastasis ENSG00000177575 ENSG00000275385 ENSG00000198053 ENSG00000104517 ENSG00000138798 ENSG00000113070 ENSG00000133110 ENSG00000272398 ENSG00000118520 ENSG00000100985 ENSG00000146648 ENSG00000150630 ENSG00000167701 PMC1600679__F7 Summary of changes in the Wnt/Beta-catenin pathway in pancreatic adenocarcinoma ENSG00000134982 ENSG00000168036 PMC9252752__F7 Inhalation of Salvianolic Acid B Prevents Fine Particulate Matter-Induced Acute Airway Inflammation and Oxidative Stress by Downregulating the LTR4/MyD88/NLRP3 Pathway ENSG00000162711 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC2760938__F13 Regulation of Lysophosphatidic Acid-induced Epidermal Growth Factor Receptor Transactivation and Interleukin-8 Secretion in Human Bronchial Epithelial Cells by Protein Kinase CD, Lyn Kinase, and Matrix Metalloproteinases ENSG00000113070 ENSG00000198670 ENSG00000146648 PMC3395887__F3 Interaction of pathogen recognition and ST2 receptor systems with FcERI leads to substantial enhancement of production of cytokines and chemokines ENSG00000137033 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000164342 PMC3348998__F1 Lipids and Prostate Cancer ENSG00000131473 ENSG00000065833 ENSG00000113161 ENSG00000169710 ENSG00000099194 ENSG00000159399 PMC10473156__F3 DNA Damage Response-Associated Cell Cycle Re-Entry and Neuronal Senescence in Brain Aging and Alzheimer’s Disease ENSG00000175054 ENSG00000138346 ENSG00000197299 ENSG00000051180 PMC5398881__F6 Scheme showing hyperglycemia-induced VEGF expression regulated by PRR, RAC1, and miRNA signaling ENSG00000164056 PMC3035994__F1 Simplified model of nutrient signaling pathways influencing metabolic responses PMC5891886__F3 Epithelial proteomic networks for TRIM28 high (a) and low (b) ratio cases ENSG00000159216 ENSG00000198793 ENSG00000146648 ENSG00000130726 PMC7562735__F10 Distribution of targets of KGEC on the comprehensive signaling pathway ENSG00000148346 ENSG00000002330 ENSG00000102871 ENSG00000198793 ENSG00000171791 ENSG00000168040 ENSG00000127191 ENSG00000100290 ENSG00000101049 ENSG00000213658 ENSG00000149968 ENSG00000135446 ENSG00000186716 ENSG00000118515 ENSG00000136869 ENSG00000100985 ENSG00000162692 PMC4905361__F2 TNFR1 signaling ENSG00000137275 ENSG00000102871 ENSG00000157625 ENSG00000083799 ENSG00000112186 PMC8086570__F5 Identification of potential genes in upper tract urothelial carcinoma using next-generation sequencing with bioinformatics and in vitro analyses ENSG00000169554 ENSG00000133937 ENSG00000160193 ENSG00000100505 ENSG00000288335 PMC7504541__F9 Hypothetical role of IL-6 in oncogenesis and tumor-associated thrombocytosis ENSG00000168610 PMC419721__F7 Schematic model of signaling events to MEKs and Erks induced by threshold concentrations of Epo ENSG00000187266 ENSG00000105723 PMC5746087__F7 miR-564 inhibits hepatocellular carcinoma cell proliferation and invasion by targeting the GRB2-ERK1/2-AKT axis ENSG00000002330 ENSG00000105401 ENSG00000198793 ENSG00000168036 PMC7915065__F1 Signaling pathways and factors involved in programmed cell death ligand-1(PD-L1)-induced resistance ENSG00000168610 ENSG00000146648 PMC7915065__F2 Key mechanisms underlying resistance to PD-L1 (1) ENSG00000100811 ENSG00000162711 ENSG00000114455 ENSG00000089692 PMC4744516__F1 Long noncoding RNAs in viral infections ENSG00000088888 ENSG00000187608 ENSG00000144895 ENSG00000185885 ENSG00000142089 ENSG00000121060 PMC4050248__F7 Protein kinase C epsilon (PKCɛ) is a major regulator of mitochondrial nicotinamide phosphoribosyltransferase (Nampt) and nicotinamide adenine dinucleotide (NAD) ENSG00000105835 PMC6537414__F6 Functional analyses of five core clusters ENSG00000112964 ENSG00000119535 ENSG00000147168 ENSG00000114737 ENSG00000198793 ENSG00000033800 ENSG00000137193 ENSG00000131095 ENSG00000171791 ENSG00000168610 ENSG00000124762 ENSG00000179295 ENSG00000100385 ENSG00000136997 ENSG00000113494 PMC10458946__F6 STING signaling pathway inhibition by STINGB in various ways and at various steps ENSG00000183735 ENSG00000164430 PMC11452178__F9 The regulation of muscle phenotypes by MSTNDel73C mutation with FGF5 knockout ENSG00000262179 ENSG00000187616 ENSG00000175592 ENSG00000129152 PMC3475613__F2 Schematic illustrating metabolic pathways prominent in malignant cells ENSG00000143158 ENSG00000136997 ENSG00000159399 ENSG00000060762 PMC9640569__F6 Genomic control of inflammation in experimental atopic dermatitis ENSG00000137033 ENSG00000145777 ENSG00000112715 PMC9526899__F3 Omega-3 supplementation on components of the endocannabinoid system and metabolic and inflammatory responses in adipose and liver of peripartum dairy cows ENSG00000009950 ENSG00000042832 ENSG00000169710 ENSG00000134780 PMC7673069__F1 Schematic presentation of the life cycle of SARS-CoV-2 in the host cell and proposed sites of famotidine action ENSG00000130234 ENSG00000184012 PMC9376585__F5 Pyroptosis in inflammation and cancer ENSG00000278718 ENSG00000162711 ENSG00000150782 ENSG00000089041 ENSG00000105483 PMC4107230__F6 Different mechanisms of signaling for EMT which might be induced by FGF10 ENSG00000070193 ENSG00000134982 ENSG00000170558 ENSG00000198793 ENSG00000123374 PMC7814631__F6 Cell signaling pathways in the epigenetic regulation of myogenesis ENSG00000100811 ENSG00000009709 ENSG00000111049 ENSG00000122180 ENSG00000142453 ENSG00000168036 ENSG00000072110 PMC7967207__F1 Tannic acid (TA) acts as a repressor for multiple proteins essential in several oncological signaling pathways ENSG00000138798 ENSG00000128342 ENSG00000168610 ENSG00000146648 PMC7945216__F7 Mechanism graph of the regulatory network and function of FoxM1-mediated miR-335-3p in NSC self-renewal ENSG00000102081 ENSG00000135446 ENSG00000123374 PMC2259464__F2 TGFB signaling pathway PMC8750186__F4 mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells ENSG00000112242 ENSG00000114126 ENSG00000198176 ENSG00000185627 ENSG00000205250 ENSG00000139687 PMC5885760__F2 Microbiome series ENSG00000119929 PMC8044581__F10 MicroRNA-1297 suppressed the Akt/GSK3B signaling pathway and stimulated neural apoptosis in an in vivo sevoflurane exposure model PMC5531511__F3 Circulating microRNAs and association with methacholine PC20 in the Childhood Asthma Management Program (CAMP) cohort ENSG00000145604 ENSG00000149311 ENSG00000087095 ENSG00000171105 ENSG00000127528 ENSG00000123374 PMC7878388__F1 HSV manipulations on the cytosolic pattern recognition receptors ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000163568 ENSG00000163565 ENSG00000168036 PMC5531511__F4 Circulating microRNAs and association with methacholine PC20 in the Childhood Asthma Management Program (CAMP) cohort ENSG00000134982 ENSG00000081051 ENSG00000132849 PMC4800863__F5 Schematic illustrations of l- and d-proline metabolism in Sinorhizobium meliloti ENSG00000228672 ENSG00000115718 PMC2704572__F1 Complement effectors generated during activation contribute to various mechanisms that limit tumor growth ENSG00000009724 ENSG00000291559 ENSG00000244731 ENSG00000166278 ENSG00000236625 PMC7884467__F1 NLRP3 inflammasome pathway ENSG00000278718 ENSG00000162711 ENSG00000133116 ENSG00000168040 ENSG00000159335 PMC2704572__F2 Some complement proteins can accelerate tumor growth ENSG00000009724 ENSG00000291559 ENSG00000244731 ENSG00000166278 ENSG00000236625 PMC6434430__F2 ERK signaling pathway was hyperactivated in the patient’s tumor tissue ENSG00000182578 ENSG00000157404 ENSG00000291603 ENSG00000002330 ENSG00000213658 ENSG00000177606 ENSG00000136997 ENSG00000134853 ENSG00000146648 ENSG00000123268 PMC5384838__F1 Vesicular acetylcholine transporter defect underlies devastating congenital myasthenia syndrome ENSG00000206561 ENSG00000198380 ENSG00000134569 ENSG00000119523 ENSG00000030304 ENSG00000172269 ENSG00000087085 ENSG00000172339 ENSG00000007314 PMC4709758__F9 Signaling pathways of IL-17A in synovial fibroblasts ENSG00000102871 ENSG00000082512 ENSG00000173039 ENSG00000172936 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC9483202__F3 Antioxidant and neuroprotective actions of resveratrol in cerebrovascular diseases ENSG00000175567 ENSG00000096717 ENSG00000079999 PMC6295097__F7 Proposed pathway of anti-tumor effects of propofol on lung cancer A549 cells ENSG00000198793 ENSG00000168036 PMC3712618__F4 Putative PGC-1-mediated mechanism of cancer-induced skeletal muscle wasting ENSG00000169047 ENSG00000198793 PMC4735260__F6 Transcriptional regulation of mitophagy ENSG00000128272 ENSG00000069509 ENSG00000185591 PMC6193900__F1 Signaling pathways and regulatory nodes that indicate novel therapeutic approaches for KRAS mutant NSCLC ENSG00000183735 ENSG00000114346 ENSG00000065361 ENSG00000291971 ENSG00000149269 ENSG00000163814 ENSG00000114315 ENSG00000077782 ENSG00000168843 ENSG00000168610 ENSG00000079999 PMC9170780__F4 Bone pain: Progress in research from bench to bedside ENSG00000178860 PMC6508148__F3 Proposed models of CST1 participating in the signaling pathways.Notes: CST1 was involved in GSK3, AKT, and IL-6 pathways ENSG00000170373 PMC8106556__F1 Targeting the alternative bile acid synthetic pathway for metabolic diseases ENSG00000160867 ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC8106556__F2 Targeting the alternative bile acid synthetic pathway for metabolic diseases ENSG00000138075 ENSG00000167910 ENSG00000180432 ENSG00000122787 ENSG00000143921 ENSG00000135929 ENSG00000026103 PMC3978875__F6 Proposed signalling interactions between C-type natriuretic peptide (CNP) and mechanical loading in chondrocytes ENSG00000125538 ENSG00000173786 ENSG00000159899 PMC11781175__F8 AS III induces autophagy and activates the nuclear translocation of Nrf2, resulting in the accumulation of p62 and autophagic flux blockade ENSG00000178573 ENSG00000079999 PMC7453787__F2 BMP-SMAD pathway and hepcidin regulation in different iron states ENSG00000121989 ENSG00000010704 ENSG00000140564 ENSG00000106327 ENSG00000187045 ENSG00000105697 ENSG00000204217 PMC7453787__F4 Crosstalk between inflammation and the BMP-SMAD pathway in hepcidin regulation ENSG00000121989 ENSG00000105697 ENSG00000168610 ENSG00000204217 ENSG00000114739 PMC6354897__F1 Key pathways interacting with theMEP pathway in chloroplast ENSG00000166278 ENSG00000062485 PMC7918730__F3 Clock and mTOR pathway interconnection ENSG00000198793 PMC4750108__F1 Working model of the innate immune sensing of tumors leading to spontaneous T cell responses in vivo ENSG00000183735 ENSG00000164430 PMC11117976__F3 NETosis in neutrophils ENSG00000265972 PMC11117976__F5 M2 macrophage polarization ENSG00000137265 ENSG00000118520 ENSG00000005381 ENSG00000105227 PMC11117976__F1 TLR and NOD receptor-mediated immune response ENSG00000162711 ENSG00000167207 ENSG00000265972 ENSG00000175104 ENSG00000106100 PMC7005297__F1 Wnt/Beta-catenin pathway in cancer stem cells ENSG00000281324 ENSG00000137673 ENSG00000106004 ENSG00000162337 ENSG00000156299 ENSG00000134982 ENSG00000155011 ENSG00000136997 ENSG00000164362 ENSG00000026508 ENSG00000167074 ENSG00000165617 PMC7005297__F2 Hedgehog signaling pathway in cancer stem cells ENSG00000094631 ENSG00000168283 ENSG00000163558 ENSG00000122691 ENSG00000090686 ENSG00000145743 ENSG00000020633 ENSG00000026508 ENSG00000164690 ENSG00000128602 PMC8508937__F3 ERB Regulation of Gonadotropin Responses during Folliculogenesis ENSG00000157500 ENSG00000138039 PMC7005297__F3 Targeting cancer stem cell pathways for cancer therapy ENSG00000168283 ENSG00000026508 ENSG00000126353 ENSG00000049768 ENSG00000127863 PMC3986830__F1 DREAM complex: Master coordinator of cell cycle dependent gene expression ENSG00000157540 ENSG00000135446 ENSG00000123374 ENSG00000150457 ENSG00000131023 ENSG00000109670 PMC11117976__F8 Immune suppression during bacterial infection ENSG00000162711 ENSG00000265972 ENSG00000074410 ENSG00000105227 PMC7177584__F3 PRDM proteins participation in signal transduction pathways, proliferation, and gene expression regulation ENSG00000112238 ENSG00000019485 ENSG00000196388 ENSG00000157933 ENSG00000147596 ENSG00000134982 ENSG00000198793 ENSG00000197632 ENSG00000169047 ENSG00000168036 ENSG00000151388 ENSG00000142611 ENSG00000177606 ENSG00000092067 ENSG00000138738 PMC6095988__F2 Androgen signaling pathway in granulosa cells of the primordial follicle ENSG00000084676 ENSG00000291971 ENSG00000129214 PMC7177584__F1 PRDM proteins contribution in the mechanisms related to invasiveness and metastasis ENSG00000112238 ENSG00000104856 ENSG00000087245 ENSG00000147596 ENSG00000186517 ENSG00000116731 ENSG00000149269 ENSG00000010810 PMC3707302__F3 Immunological synapse: the gateway to the HIV reservoir ENSG00000133961 ENSG00000137845 PMC5427056__F1 Molecular Pathways: Increased Susceptibility to Infection Is a Complication of mTOR Inhibitor Use in Cancer Therapy ENSG00000177169 ENSG00000150907 ENSG00000169047 ENSG00000118515 ENSG00000155792 ENSG00000196712 PMC5464113__F2 Genes found to modulate the accumulation and secretion of different aggregated species of aSyn ENSG00000103769 ENSG00000166128 PMC8725311__F2 Combination therapy with immune checkpoint inhibitors (ICIs); a new frontier ENSG00000002330 ENSG00000177606 ENSG00000136997 PMC5688955__F1 Diagram showing the various effects as well as the different pathways activated by ouabain in ADPKD cells ENSG00000291971 ENSG00000001626 ENSG00000146648 PMC6221947__F1 Polyamine Pathway and Reaction Mechanism of DHS ENSG00000112977 ENSG00000288145 ENSG00000129932 PMC8630681__F8 Proteome Analysis of Camellia nitidissima Chi Revealed Its Role in Colon Cancer Through the Apoptosis and Ferroptosis Pathway ENSG00000168003 ENSG00000167468 PMC4016715__F2 Ciliary-vesicle-dependent steps of ciliogenesis, and modular organization and mechanism of the IFT machinery ENSG00000047410 ENSG00000118096 ENSG00000101052 ENSG00000128581 ENSG00000068885 ENSG00000174483 ENSG00000119650 ENSG00000114446 ENSG00000138686 ENSG00000206418 ENSG00000081870 ENSG00000140463 ENSG00000138002 ENSG00000109083 ENSG00000122507 ENSG00000187535 ENSG00000096872 ENSG00000119396 ENSG00000122970 PMC4016715__F3 Model depicting ciliary cargo trafficking pathways ENSG00000140463 ENSG00000109083 ENSG00000138175 ENSG00000156313 ENSG00000168374 ENSG00000113966 ENSG00000113971 ENSG00000109103 ENSG00000078674 PMC9376585__F1 Pyroptosis in inflammation and cancer ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000091592 ENSG00000091106 PMC9376585__F2 Pyroptosis in inflammation and cancer ENSG00000162711 ENSG00000158828 ENSG00000091592 ENSG00000276561 ENSG00000277571 ENSG00000164430 ENSG00000167468 ENSG00000125538 ENSG00000105483 ENSG00000142731 ENSG00000124181 ENSG00000142002 ENSG00000215301 PMC6696194__F8 Signaling pathway for GSSA via SCARB1 receptor from CD19+ lymphocyte ENSG00000095585 ENSG00000186716 PMC9500586__F3 Personalized nutrition: A review of genotype-based nutritional supplementation ENSG00000184254 ENSG00000128918 ENSG00000162496 PMC11892138__F7 Eugenol accelerates intestinal stem cell regeneration to protect the intestinal barrier integrity through inhibiting JAK2/STAT3 signaling pathway in Salmonella enteritidis-challenged broiler chicks ENSG00000168610 PMC6761967__F5 Whole driver PC3-represented PCa signaling pathway ENSG00000104856 ENSG00000138795 ENSG00000117425 ENSG00000170214 ENSG00000198793 ENSG00000196470 ENSG00000100346 ENSG00000095585 ENSG00000131876 ENSG00000110395 ENSG00000114126 ENSG00000127533 ENSG00000148082 ENSG00000198670 ENSG00000178719 ENSG00000188677 ENSG00000137267 PMC6829248__F2 Summary of natural product regulation in proteostasis machinery ENSG00000198793 ENSG00000139687 PMC3443258__F6A An inventory of peroxisomal proteins and pathways in Drosophila melanogaster ENSG00000018510 ENSG00000116906 PMC8834581__F3 Functional Coordination among the Golgi Complex, the Centrosome and the Microtubule Cytoskeleton during the Cell Cycle ENSG00000291971 ENSG00000145321 PMC6305227__F1 Propionibacterium acnes: loss of diversity, selection of phylotypes, and its different target activities in acne ENSG00000026508 PMC6639256__F7 READ pathways (p53 signaling pathway, intestinal immune network for IgA production, and colorectal cancer pathway) enriched in DEmRNAs during READ ENSG00000149311 ENSG00000002330 ENSG00000134982 PMC3329340__F3 Simplified TOR signaling network with known Arabidopsis homologs in Italic writing ENSG00000164327 ENSG00000167965 PMC5469033__F1 Adipose Tissue NAD+ Biology in Obesity and Insulin Resistance: From Mechanism to Therapy ENSG00000187531 ENSG00000105835 ENSG00000123572 ENSG00000278488 ENSG00000124523 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000089163 ENSG00000283100 PMC9928999__F2 Regulatory effects of oral microbe on intestinal microbiota and the illness ENSG00000163220 ENSG00000136869 ENSG00000277401 ENSG00000115009 PMC8419056__F3 Inflammation-related pyroptosis, a novel programmed cell death pathway, and its crosstalk with immune therapy in cancer treatment ENSG00000162711 ENSG00000189403 ENSG00000136869 ENSG00000146648 ENSG00000073605 PMC8419056__F2 Inflammation-related pyroptosis, a novel programmed cell death pathway, and its crosstalk with immune therapy in cancer treatment ENSG00000162711 ENSG00000189403 ENSG00000168610 ENSG00000147697 PMC5079533__F4 Ingenuity pathway analysis of endocrine networks depicted in through ENSG00000110711 ENSG00000171105 ENSG00000242252 ENSG00000143839 ENSG00000110680 ENSG00000036828 ENSG00000171388 ENSG00000087460 ENSG00000066468 ENSG00000118785 ENSG00000130234 ENSG00000133116 ENSG00000019186 ENSG00000170893 ENSG00000077782 PMC7577320__F1 Malic Enzyme 1 (ME1) in the Biology of Cancer: It’s not Just Intermediary Metabolism ENSG00000131473 ENSG00000151376 ENSG00000169710 ENSG00000082212 PMC3472558__F1 EGFR signaling pathway (reprinted with permission from BioCarta Pathways ENSG00000138798 ENSG00000168610 PMC10644365__F2 Signaling pathways associated with ERA ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC4688235__F2 Recent advances on viral manipulation of NFKB signaling pathway ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000163565 ENSG00000172936 ENSG00000164342 PMC6293255__F5 Top two networks (A and B) identified by Ingenuity Pathway Analysis as overrepresented within the list of 245 genes (P < 0.005) dysregulated in human IAPP transgenic (HIP) vs ENSG00000108691 ENSG00000011422 ENSG00000197632 ENSG00000162772 ENSG00000132170 ENSG00000135919 PMC6277408__F4 Analysis of p53-pathway in relation to miRNA expression and potential targets ENSG00000132906 ENSG00000164305 PMC8631789__F5 Overt Acute Hepatitis B Deteriorates in Females: Destructive Immunity With an Exaggerated Interleukin-17 Pathway ENSG00000111537 ENSG00000113520 PMC2494844__F2 Genomic dissection of the cytokine-controlled STAT5 signaling network in liver ENSG00000120833 ENSG00000112964 PMC3089989__F2 Gene expression pattern of the P38 MAPK signaling pathway ENSG00000162889 ENSG00000145365 ENSG00000127191 ENSG00000114738 PMC4688235__F1 Recent advances on viral manipulation of NFKB signaling pathway ENSG00000174125 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000163565 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC9102649__F4 Silencing oncogene cell division cycle associated 5 induces apoptosis and G1 phase arrest of non‐small cell lung cancer cells via p53‐p21 signaling pathway ENSG00000146670 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC9460126__F7 Vasorin Deletion in C57BL/6J Mice Induces Hepatocyte Autophagy through Glycogen-Mediated mTOR Regulation ENSG00000177169 ENSG00000274334 ENSG00000198793 PMC11795593__F7 Transcriptomic and metabolomic-based revelation of the effect of fresh corn extract on meat quality of Jingyuan chicken ENSG00000172292 ENSG00000164023 PMC7136521__F1 Angiogenic and vasculogenic mimicry promotion by CSCs is mainly triggered by VEGF among several types of cancer ENSG00000183625 ENSG00000174059 ENSG00000168610 PMC11989355__F4 KEGG pathway diagram ENSG00000127948 PMC4088997__F5 Rapamycin and paclitaxel nanoparticles synergistically target the PI3K/Akt/mTOR pathway by suppressing feedback loop Akt phosphorylation ENSG00000002330 ENSG00000169047 PMC5687841__F6 Genetic dissection of the impact of miR-33a and miR-33b during the progression of atherosclerosis ENSG00000104856 ENSG00000291603 ENSG00000138798 ENSG00000197632 ENSG00000173039 ENSG00000165280 ENSG00000162924 ENSG00000111321 ENSG00000150455 ENSG00000226275 ENSG00000163235 ENSG00000157625 ENSG00000172936 PMC5474292__F3 Nodes linking the enriched KEGG pathway by hub genes ENSG00000160789 ENSG00000166167 ENSG00000171105 ENSG00000169047 ENSG00000100345 ENSG00000099860 ENSG00000166851 ENSG00000167900 ENSG00000007171 ENSG00000132170 ENSG00000077150 ENSG00000120899 ENSG00000177606 ENSG00000136997 ENSG00000113520 ENSG00000123374 ENSG00000136160 ENSG00000146648 PMC4614816__F1 Cells express exosomes comprising lipids however lipids impact on cancer cells according to cell phenotype ENSG00000148400 ENSG00000121966 PMC9354757__F1 Profile of Glasdegib for the Treatment of Newly Diagnosed Acute Myeloid Leukemia (AML): Evidence to Date ENSG00000106571 ENSG00000128602 PMC9406051__F9 Genomic Aberrations Generate Fusion Gene FOXK2::TP63 and Activate NFKB1 in Cutaneous T-Cell Lymphoma ENSG00000109332 ENSG00000168214 ENSG00000109320 ENSG00000137265 ENSG00000145349 ENSG00000167861 PMC4107453__F8 Role of the SIK2-p35-PJA2 complex in pancreatic beta cell functional compensation ENSG00000198961 ENSG00000170145 PMC3634440__F1 Gene regulatory networks of plant transcription factors (TFs) in plant abiotic stress responses and abscisic acid-dependent gene expression ENSG00000105722 ENSG00000163788 PMC9352922__F3 PKCA and PKCD: Friends and Rivals ENSG00000291971 ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000101224 PMC6425079__F1 Schematic diagram depicting proposed mechanisms responsible for aniline inducedspleen toxicity ENSG00000109674 ENSG00000292286 ENSG00000115008 ENSG00000140398 PMC10995224__F2 Signaling pathway that was affected by ridaforolimus ENSG00000081913 ENSG00000198793 ENSG00000155792 ENSG00000040199 PMC9304707__F2 What we have learnt from Drosophila model organism: the coordination between insulin signaling pathway and tumor cells ENSG00000171720 ENSG00000146648 PMC12037492__F1 Mechanisms via which TYMP promotes platelet activation and osteoclast differentiation ENSG00000010810 ENSG00000175104 ENSG00000131196 PMC4770095__F2 Regulation of Th2 Cell Immunity by Dendritic Cells ENSG00000140968 ENSG00000137265 ENSG00000126353 ENSG00000136826 PMC2731164__F7 Embryonic Stem Cell Differentiation ENSG00000112576 ENSG00000002330 ENSG00000102871 ENSG00000120889 ENSG00000129355 ENSG00000112118 ENSG00000135476 ENSG00000205250 ENSG00000073111 ENSG00000277273 ENSG00000076003 ENSG00000118971 ENSG00000166851 ENSG00000124762 ENSG00000183765 ENSG00000160049 ENSG00000105325 ENSG00000123374 ENSG00000120868 ENSG00000090376 ENSG00000139687 ENSG00000064012 ENSG00000115594 ENSG00000253729 ENSG00000026103 ENSG00000023445 ENSG00000005339 ENSG00000100906 ENSG00000175793 ENSG00000137275 ENSG00000138794 ENSG00000173039 ENSG00000213341 ENSG00000101224 ENSG00000006062 ENSG00000117399 ENSG00000077935 ENSG00000149311 ENSG00000291983 ENSG00000094804 ENSG00000156970 ENSG00000134070 ENSG00000172936 ENSG00000149554 ENSG00000080839 PMC12037492__F3 Mechanism via which TYMP modifies epigenetic and resists apoptosis TYMP catalyzes the conversion of thymidine to thymine and 2DDR, which binds to integrin AVB3/A5B1 on progenitor cells, thereby activating the PI3K pathway ENSG00000140968 PMC5321802__F2 Regulation of hepcidin expression in hepatocytes in response to iron status and requirements (left) or inflammation (right) ENSG00000168610 PMC9326259__F9 Mechanism and Molecular Targets of Ejiao Siwu Decoction for Treating Primary Immune Thrombocytopenia Based on High-Performance Liquid Chromatograph, Network Pharmacology, Molecular Docking and Cytokines Validation ENSG00000177455 ENSG00000003436 ENSG00000110799 ENSG00000080618 ENSG00000088926 ENSG00000117322 ENSG00000185010 ENSG00000062485 PMC8113755__F1 WNT plasma membrane signaling in PDAC ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000136997 ENSG00000102312 ENSG00000168036 ENSG00000108375 PMC6493202__F6 Neuroprotection by Sildenafil PMC7408575__F2 JAK-STAT canonical signaling pathway ENSG00000162892 ENSG00000142224 PMC5703970__F3 C-T-P network ENSG00000180210 ENSG00000087245 ENSG00000164742 ENSG00000142192 ENSG00000101188 ENSG00000180772 ENSG00000095303 ENSG00000143933 ENSG00000100985 ENSG00000073756 ENSG00000102468 ENSG00000007171 PMC5703970__F4 Neuroinflammation pathway and therapeutic modules ENSG00000109163 ENSG00000087245 ENSG00000164742 ENSG00000142192 ENSG00000002330 ENSG00000070831 ENSG00000291971 ENSG00000095303 ENSG00000073756 ENSG00000164305 ENSG00000102468 ENSG00000007171 PMC7795265__F6A Proteomic Profiling of the First Human Dental Pulp Mesenchymal Stem/Stromal Cells from Carbonic Anhydrase II Deficiency Osteopetrosis Patients ENSG00000065135 ENSG00000110711 ENSG00000115548 ENSG00000065978 ENSG00000106333 ENSG00000170266 ENSG00000196154 ENSG00000073712 ENSG00000198125 ENSG00000152952 PMC9646750__F1 Advances in multi-omics study of biomarkers of glycolipid metabolism disorder ENSG00000006071 ENSG00000197635 ENSG00000100344 ENSG00000168036 PMC3003706__F7 Distinct B1 and B3 integrin pathways converge to regulate cross-linked actin network (CLAN) formation in human trabecular meshwork (HTM) cells ENSG00000038382 ENSG00000291971 PMC478571__F3 Chart of cell cycle genes ENSG00000112118 ENSG00000091651 ENSG00000073111 ENSG00000277273 ENSG00000145386 ENSG00000076003 ENSG00000134480 ENSG00000093009 ENSG00000145604 ENSG00000094804 ENSG00000135446 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000139687 ENSG00000175305 PMC4232069__F2 A FOXO3-driven pathway abrogates inflammatory responses in a transforming growth factor (TGF)B1-dependent manner ENSG00000105329 ENSG00000125538 PMC8082541__F1 Natural Bioactive Compounds as Potential Browning Agents in White Adipose Tissue ENSG00000142611 ENSG00000096717 ENSG00000196689 PMC8616505__F2 Interplay between the Unfolded Protein Response, Inflammation and Infection in Cystic Fibrosis ENSG00000128272 ENSG00000147862 ENSG00000100219 ENSG00000127191 PMC7798015__F4 Direct and indirect intracellular effects of CCN proteins in chronic myeloid leukemia (CML) ENSG00000104415 ENSG00000136999 ENSG00000148400 ENSG00000109320 PMC8299052__F4 MCU-Dependent mROS Generation Regulates Cell Metabolism and Cell Death Modulated by the AMPK/PGC-1A/SIRT3 Signaling Pathway ENSG00000156026 ENSG00000142082 PMC7798015__F2 Complex regulation of CCN2 expression, and the diverse actions of the CCN2 protein, as reported in literature ENSG00000136999 ENSG00000197081 ENSG00000110799 ENSG00000164935 ENSG00000163914 ENSG00000146648 PMC8299052__F1 MCU-Dependent mROS Generation Regulates Cell Metabolism and Cell Death Modulated by the AMPK/PGC-1A/SIRT3 Signaling Pathway ENSG00000005059 ENSG00000107745 ENSG00000156026 PMC9695228__F11 Gotta Go Slow: Two Evolutionarily Distinct Annelids Retain a Common Hedgehog Pathway Composition, Outlining Its Pan-Bilaterian Core ENSG00000064309 ENSG00000180447 ENSG00000165115 ENSG00000144857 ENSG00000128602 PMC11520086__F3 Metabolic pathway and enzyme gene expression difference of C1 compounds in the transcriptome group, Formaldehyde vs ENSG00000122966 ENSG00000109534 ENSG00000178922 PMC7010578__F4 Major pathways and genes related to major depressive disorder (MDD) ENSG00000144063 ENSG00000184845 ENSG00000163235 ENSG00000164305 ENSG00000149295 PMC6186337__F1 In this figure, we consider potential mechanisms regulated by physical activity and caloric restriction in inhibiting the mTOR pathway ENSG00000198793 ENSG00000140443 PMC3657575__F10 The signaling pathways involved in calpain-mediated regulation of dendritic protein synthesis induced by BDNF ENSG00000198793 PMC5635727__F2 Lut alleviates I/R injury by inhibiting apoptosis by up-regulating AKT, increasing BCL-2 protein and decreasing BAX protein ENSG00000079999 PMC6323179__F6 Proteome changes in (A) G-protein signaling pathway, (B) calcium signaling pathway and (C) ginsenoside synthesis pathway and (D) ribosomes biogenesis, ubiquitin-mediated proteolysis and RNA transport pathway ENSG00000163435 ENSG00000173599 ENSG00000197429 ENSG00000113569 ENSG00000291973 ENSG00000132341 PMC8953452__F1 HOG pathway and the regulation of osmoadaptive responses in yeast ENSG00000039537 ENSG00000260314 ENSG00000136425 ENSG00000141977 ENSG00000157884 ENSG00000166278 PMC5390025__F2 Host-Helminth interaction: There are two sides of immune response against a parasite invasion, one leads to worm survival in host and the other to worm killing ENSG00000137033 ENSG00000118520 ENSG00000166090 PMC7830946__F7 Nuclear factor erythroid 2 (NEF2)-related factor 2 (Nrf2) signaling pathway of oxidative stress ENSG00000079999 PMC3110895__F4 Modeled miRNA mediated pathways in the pathogenesis of lung fibrosis ENSG00000134982 ENSG00000026103 PMC2634254__F2 Embryonic liver development ENSG00000019991 ENSG00000117707 ENSG00000081051 ENSG00000163631 PMC4013402__F1 Glucose and glutamine metabolism in cancer cells ENSG00000139514 ENSG00000100170 ENSG00000115419 PMC2634254__F4 Upstream regulators and downstream targets of Beta-catenin during embryonic liver development ENSG00000070193 ENSG00000120057 ENSG00000168036 PMC4889573__F2 cAMP intracellular signaling pathways in target cells of Treg suppression ENSG00000112149 ENSG00000131196 PMC4138319__F3 miRNA- and TF-mediated sub-network specific to the TGFB signaling pathway ENSG00000198648 ENSG00000107742 ENSG00000174804 ENSG00000139926 ENSG00000172403 ENSG00000133401 ENSG00000125347 ENSG00000081026 ENSG00000157227 ENSG00000135446 ENSG00000105810 ENSG00000111371 ENSG00000136205 PMC7915382__F1 Aldosterone signaling pathway most significantly affected by oregano with 19 genes ENSG00000069869 ENSG00000095321 ENSG00000116237 PMC7188969__F2 CD36 in Type 2 Diabetes Mellitus: Beta-Cell Dysfunction and Beyond ENSG00000162711 ENSG00000135218 ENSG00000291971 ENSG00000265972 PMC8042171__F2 Genetic glycoengineering in mammalian cells ENSG00000033011 ENSG00000111728 ENSG00000160408 ENSG00000109586 ENSG00000128268 ENSG00000174607 ENSG00000109956 ENSG00000285395 ENSG00000119523 ENSG00000198108 ENSG00000139629 ENSG00000214160 ENSG00000113532 ENSG00000187210 ENSG00000147162 ENSG00000176597 ENSG00000008513 ENSG00000135454 ENSG00000285222 ENSG00000070731 ENSG00000166278 ENSG00000281879 ENSG00000115525 ENSG00000179104 ENSG00000126091 ENSG00000181027 ENSG00000140297 ENSG00000282880 ENSG00000158008 ENSG00000136731 ENSG00000167080 ENSG00000130035 ENSG00000033100 ENSG00000069482 ENSG00000143315 ENSG00000164574 ENSG00000123989 ENSG00000060642 ENSG00000101638 ENSG00000148488 ENSG00000070526 ENSG00000172986 ENSG00000125247 ENSG00000151233 ENSG00000130309 ENSG00000257594 ENSG00000148154 ENSG00000165905 ENSG00000170340 ENSG00000173852 ENSG00000136542 ENSG00000069943 ENSG00000178904 ENSG00000118600 ENSG00000121578 ENSG00000172318 ENSG00000131446 ENSG00000182197 ENSG00000134910 ENSG00000106397 ENSG00000115339 ENSG00000156966 ENSG00000133687 ENSG00000176928 ENSG00000167889 ENSG00000237172 ENSG00000156162 ENSG00000187676 ENSG00000179913 ENSG00000131873 ENSG00000178202 ENSG00000134901 ENSG00000176383 ENSG00000177990 ENSG00000147408 ENSG00000173950 ENSG00000119514 ENSG00000288490 ENSG00000168282 ENSG00000177191 ENSG00000205301 ENSG00000101901 ENSG00000064225 ENSG00000100060 ENSG00000106003 ENSG00000139133 ENSG00000196371 ENSG00000159063 ENSG00000163527 ENSG00000101346 ENSG00000180549 ENSG00000158470 ENSG00000130383 ENSG00000198488 ENSG00000186866 PMC7142254__F3 Targeting USP7-MDM2/MDMX-p53 network for cancer therapy ENSG00000159921 PMC4259860__F7 Differential proteomic profiling unveils new molecular mechanisms associated with mitochondrial complex III deficiency ENSG00000074800 ENSG00000100714 ENSG00000129515 ENSG00000198931 ENSG00000091140 PMC2888385__F6 Nodal-Smad2 signaling regulation of the BMP pluripotency pathway in mouse ES cells ENSG00000183734 ENSG00000156574 ENSG00000179348 PMC3479343__F7 Placental PPARG Regulates Spatiotemporally Diverse Genes And A Unique Metabolic Network ENSG00000042832 ENSG00000172992 ENSG00000285482 PMC5831804__F1 Major players implicated in the phenotypes associated with the deletion of GUP1 in S ENSG00000070831 ENSG00000228278 ENSG00000159263 ENSG00000149489 ENSG00000229314 ENSG00000197601 PMC8891816__F2 miR-221/222 as biomarkers and targets for therapeutic intervention on cancer and other diseases: A systematic review ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 ENSG00000168610 PMC2538516__F1 Biosynthetic relationships between amino acids, as defined by their biosyntheses and their relationships with the glycolytic pathway and the citric acid cycle ENSG00000112977 ENSG00000163794 ENSG00000179168 ENSG00000143375 PMC9485267__F1 Targeting p85B nuclear translocation for the tumors with PIK3CA helical domain mutations ENSG00000150672 ENSG00000108799 ENSG00000169047 PMC8153134__F2 Molecular Basis of Calcium and Phosphorus Inherited Metabolic Disorders ENSG00000111012 ENSG00000118972 ENSG00000152266 ENSG00000019186 ENSG00000186104 ENSG00000135929 PMC5827181__F2 Toward novel ways of MALT1 activation? ENSG00000186716 ENSG00000082512 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000076604 PMC5827181__F1 The waves of MALT1 activation ENSG00000175104 ENSG00000198286 PMC9001993__F5 2-Methoxy-1,4-naphthoquinone (MNQ) regulates cancer key genes of MAPK, PI3K, and NFKB pathways in Raji cells ENSG00000077150 ENSG00000002330 ENSG00000157764 ENSG00000109320 ENSG00000102871 ENSG00000150907 ENSG00000109270 ENSG00000150093 ENSG00000139687 PMC6311529__F7 Proposed model of LUBAC-mediated ubiquitination on cFLIP in the TNFA receptor signaling pathway ENSG00000137275 ENSG00000102871 ENSG00000082512 ENSG00000285152 ENSG00000168040 ENSG00000127191 PMC4027966__F3 Thiopurine pharmacogenomics: association of SNPs with clinical response and functional validation of candidate genes ENSG00000137364 ENSG00000011260 ENSG00000182220 ENSG00000156113 ENSG00000186469 PMC5960485__F8 Network showing the most important gene interactions for the “regulation of canonical WNT signaling” (GO term GO:0060828) pathway ENSG00000107404 ENSG00000138795 ENSG00000162337 ENSG00000168646 ENSG00000125084 ENSG00000123908 PMC7731198__F4 Novel mechanism of lysostaphin resistance in ST72 isolate and its associated metabolic pathway ENSG00000228716 ENSG00000095059 PMC6198057__F1 Scheme depicting the main upstream and downstream regulators of mTORC1 signaling pathway ENSG00000159224 ENSG00000171791 ENSG00000096717 PMC7991912__F2 Pathway overrepresentation and gene ontology analysis of cisplatin-induced significantly deregulated proteins ENSG00000168028 ENSG00000265681 ENSG00000164587 ENSG00000162244 ENSG00000198242 ENSG00000147604 ENSG00000169710 ENSG00000136942 ENSG00000130255 ENSG00000008988 ENSG00000102034 ENSG00000092621 ENSG00000090861 ENSG00000142669 PMC7491384__F3 Dietary Regulation of Immunity ENSG00000162711 ENSG00000144895 PMC10141597__F1 Profiling Germinal Center-like B Cell Responses to Conjugate Vaccines Using Synthetic Immune Organoids ENSG00000197971 ENSG00000186716 PMC7965690__F4 How MARylation is predicted to be involved in the regulation of colorectal cancer ENSG00000134982 ENSG00000168036 ENSG00000172264 ENSG00000106546 PMC2874225__F1 The DSBR and SDSA meiotic recombination models ENSG00000051180 ENSG00000100206 ENSG00000054796 PMC5715672__F3 Pathway of catecholamine biosynthesis ENSG00000123454 ENSG00000141744 PMC7436979__F6 Components-Targets-pathway network ENSG00000138798 ENSG00000173039 ENSG00000171791 ENSG00000112715 ENSG00000073756 ENSG00000164305 ENSG00000007171 ENSG00000111537 ENSG00000177606 ENSG00000125538 ENSG00000136869 ENSG00000100985 ENSG00000146648 PMC5500762__F3 Lysine acetylation events involved in carbon fixation (A), tricarboxylic acid cycle (B), and photosynthetic pathway (C) ENSG00000070444 ENSG00000182511 ENSG00000073578 ENSG00000117118 ENSG00000153574 ENSG00000062485 PMC3465263__F10 Wortmannin Reduces Insulin Signaling and Death in Seizure-Prone Pcmt1−/− Mice ENSG00000120265 PMC3479191__F5 Multilevel factors cooperatively perturb pathways ENSG00000107779 ENSG00000139269 ENSG00000163083 ENSG00000124762 ENSG00000068028 ENSG00000074211 ENSG00000170365 ENSG00000105664 ENSG00000198742 ENSG00000136997 ENSG00000133740 ENSG00000139687 ENSG00000282899 ENSG00000172201 PMC11281550__F6 Changes in metabolites in PI3K/AKT/FOXO signaling pathway after TeA, PAT alone, and combined exposure ENSG00000145604 ENSG00000149311 ENSG00000087095 ENSG00000171105 ENSG00000127528 ENSG00000123374 ENSG00000096717 ENSG00000145782 ENSG00000168610 ENSG00000146648 PMC5996928__F5 Molecular signaling pathways involved in astrocyte reaction in AD ENSG00000150782 ENSG00000168610 PMC3466807__F1 BOLERO-2 trial: the addition of everolimus to exemestane in the treatment of postmenopausal hormone receptor-positive advanced breast cancer ENSG00000198793 PMC3604893__F1 A) Model of multi-agent vs ENSG00000186716 ENSG00000275565 PMC4713514__F5 Focal adhesion pathway analysis based on the KEGG database ENSG00000169291 ENSG00000002330 ENSG00000010810 PMC9630602__F2 Negative regulator NLRC3: Its potential role and regulatory mechanism in immune response and immune-related diseases ENSG00000278718 ENSG00000162711 ENSG00000150907 ENSG00000172936 ENSG00000175104 PMC9630602__F4 Negative regulator NLRC3: Its potential role and regulatory mechanism in immune response and immune-related diseases ENSG00000183735 ENSG00000175104 PMC12185430__F2 Gut microbiota-derived metabolites in MASLD pathogenesis under dysbiosis ENSG00000170458 ENSG00000198793 ENSG00000130649 ENSG00000136869 ENSG00000106546 PMC12185430__F3 Botanical drugs-mediated immunomodulation through LPS/TLR4 signaling ENSG00000172936 ENSG00000136869 PMC5635727__F3 In HF, SERCA2a is a vital target regulated by Lut for effective cardiomyocyte contraction and relaxation ENSG00000116030 PMC12185430__F1 Mechanistic framework of the “multiple-hit” hypothesis in MASLD progression The pathogenesis of MASLD involves sequential pathological hits driving progression from hepatic steatosis to end-stage liver injury ENSG00000042832 ENSG00000136869 PMC12205216__F2 Natural products downregulating TGF‐B pathway in treatment of leukemia ENSG00000136807 ENSG00000135446 PMC7397827__F1 Killer Pseudokinase Mixed Lineage Kinase Domain-Like Protein (MLKL) ENSG00000137275 ENSG00000168404 ENSG00000164342 PMC6945981__F5 Effects of perlecan deficiency on transcriptome changes in (A) the 1-day study groups and (B) the 7-day study groups ENSG00000136457 ENSG00000110799 ENSG00000111837 PMC6030166__F6 Combined network analysis of metabolites and lipids ENSG00000172831 ENSG00000073578 ENSG00000153094 ENSG00000079432 ENSG00000121879 ENSG00000070669 ENSG00000128050 ENSG00000086205 ENSG00000198380 ENSG00000150991 ENSG00000136997 ENSG00000106305 ENSG00000116120 ENSG00000114999 ENSG00000125166 ENSG00000180185 ENSG00000131473 ENSG00000124608 ENSG00000141401 ENSG00000167900 ENSG00000073756 ENSG00000023909 ENSG00000102977 ENSG00000151224 ENSG00000156802 ENSG00000292099 ENSG00000164023 ENSG00000041357 PMC4770165__F1 Aryl hydrocarbon receptor signaling pathway is depicted with 3,3′-diindolylmethane as a model agonist ENSG00000140505 ENSG00000140465 ENSG00000106546 PMC6030166__F8 Central carbon metabolism in cancer ENSG00000131473 ENSG00000136997 ENSG00000105656 ENSG00000105953 ENSG00000078237 ENSG00000077463 ENSG00000119912 ENSG00000142082 ENSG00000115419 ENSG00000141526 PMC7397827__F5 Killer Pseudokinase Mixed Lineage Kinase Domain-Like Protein (MLKL) ENSG00000124256 ENSG00000168404 ENSG00000164342 PMC12205216__F3 Natural products upregulating TGF‐B pathway in treatment of leukemia PMC12205216__F4 Natural products targeting TGF‐B pathway in treatment of colorectal cancer PMC8269285__F10 Monosomy 3 Is Linked to Resistance to MEK Inhibitors in Uveal Melanoma ENSG00000180210 ENSG00000084093 ENSG00000172005 ENSG00000162772 ENSG00000112715 PMC5384023__F7 tmTNF-Alpha-induced STAT1-dependent apoptotic signaling via TNFR1 ENSG00000115415 ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC11662063__F6 Proposed model suggests that SS18-SSX drives the acitivation ofTYK2/STAT3/Bcl2 axisthereby mediating apoptosis evasion in SS cells ENSG00000105397 ENSG00000171791 ENSG00000168610 PMC5414786__F7 Components of insulin signaling pathway and the up-regulated genes with H3K27ac- or H3K4me3-increased regions by decidualization ENSG00000169291 ENSG00000171105 ENSG00000110395 ENSG00000150907 ENSG00000198793 ENSG00000026103 PMC3261278__F1 Synaptic translation and signaling pathways modulated by FMRP (a) and dysregulation of these pathways in the absence or significant reduction of FMRP (b) ENSG00000142192 ENSG00000150672 ENSG00000198576 ENSG00000100985 PMC3261278__F2 Targeted treatments for fragile X syndrome ENSG00000198793 ENSG00000198576 ENSG00000288461 PMC7034838__F3 Iron metabolic pathways in the processes of sponge plasticity ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000188690 PMC11728517__F4 Extrinsic and intrinsic apoptosis pathway ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC8229991__F2 Activin-A Induces Early Differential Gene Expression Exclusively in Periodontal Ligament Fibroblasts from Fibrodysplasia Ossificans Progressiva Patients ENSG00000121989 ENSG00000170365 ENSG00000123612 ENSG00000120693 ENSG00000070404 ENSG00000163083 ENSG00000134363 ENSG00000204217 ENSG00000114739 PMC11954783__F2 Review of recent molecular pathology of bladder urothelial carcinoma ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000133067 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC7509150__F5 KEGG analysis for signaling pathways ENSG00000090402 ENSG00000167207 ENSG00000102871 ENSG00000163739 ENSG00000183979 ENSG00000007908 ENSG00000168040 ENSG00000150455 ENSG00000127191 ENSG00000095585 ENSG00000149311 ENSG00000226275 ENSG00000213658 ENSG00000170458 ENSG00000149968 ENSG00000186716 ENSG00000177606 ENSG00000198670 ENSG00000131323 ENSG00000128342 ENSG00000175104 PMC6414514__F4 Dynamic mechanism of ADP-ribosylation reversal ENSG00000133315 ENSG00000165609 ENSG00000198585 ENSG00000198793 ENSG00000227345 PMC7556678__F1 Thromboinflammatory pathways in sickle cell disease ENSG00000110799 ENSG00000136869 PMC9559307__F1 Biomarkers in the Management of Colorectal Liver Metastases ENSG00000002330 ENSG00000134982 ENSG00000138798 ENSG00000168036 ENSG00000140443 PMC3156642__F1 Crosstalk between the canonical and non-canonical transforming growth factor-beta1 (TGFB1) and myostatin pathways PMC12139502__F2 Proteome features of the four major heart cell-types ENSG00000157554 ENSG00000109061 ENSG00000152661 ENSG00000142798 ENSG00000006788 ENSG00000198561 ENSG00000118680 ENSG00000184113 ENSG00000168036 ENSG00000076706 ENSG00000198626 ENSG00000197616 ENSG00000173402 ENSG00000007171 ENSG00000261371 ENSG00000092054 ENSG00000118520 ENSG00000154721 ENSG00000036473 ENSG00000179348 PMC6102278__F8 Fas-mediated EGF-induced EGFR signaling A proposed model of the robust EGF-induced EGFR signaling pathway mediated by the pro-survival, phosphorylated Fas that can lead to aggressive behavior of cancer cells is presented here ENSG00000291971 ENSG00000138798 ENSG00000176105 ENSG00000168610 ENSG00000146648 ENSG00000026103 PMC1876696__F1 Pathways for the synthesis of the major phospholipids in S ENSG00000042832 ENSG00000173599 ENSG00000197429 ENSG00000133027 PMC10928192__F1 TNF/TNFR1 signalling through complex I ENSG00000137275 ENSG00000102871 ENSG00000127191 PMC10928192__F2 TNF/TNFR1 signalling through complex II ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC10928192__F3 Interplay between TNF/TNFR1 complex I and complex II signalling pathways ENSG00000137275 ENSG00000102871 ENSG00000157625 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC5058780__F2 FAK and paxillin, two potential targets in pancreatic cancer ENSG00000291971 ENSG00000163914 PMC6902872__F1 Pathway to chronic rapamycin therapy in prostate cancerModel: Chronic mTORC1 inhibition delays of PCa progression from active surveillance ENSG00000198793 ENSG00000167658 PMC11744640__F6 Molecular mechanisms of SARS‐CoV‐2‐induced pulmonary fibrosis ENSG00000111537 ENSG00000130234 ENSG00000184012 PMC11744640__F8 Canonical and noncanonical TGF‐B signaling pathways ENSG00000198793 ENSG00000076604 PMC11744640__F9 Important signaling pathways involved in fibrosis ENSG00000164430 ENSG00000128272 ENSG00000137070 ENSG00000168036 ENSG00000100219 ENSG00000128602 PMC308804__F4 Visualizing protein interaction networks in HPRD ENSG00000172216 ENSG00000291971 ENSG00000128052 ENSG00000115904 ENSG00000082556 ENSG00000099942 PMC5173100__F8 Novel arylbenzofuran induces cervical cancer cell apoptosis and G1/S arrest through ERK-mediated Cdk2/cyclin-A signaling pathway ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000145386 PMC7828713__F2 Microglial regulation of neuronal networks and CNS homeostasis ENSG00000168329 PMC3896667__F5 Significantly altered pathway in primary tumor ENSG00000175054 ENSG00000137673 ENSG00000110395 ENSG00000136997 ENSG00000134853 ENSG00000139687 ENSG00000253729 ENSG00000172037 PMC4013180__F3 Multiple pathways can stimulate Beta-cell replication in obesity, and there is overlap of many of the downstream activators ENSG00000019991 ENSG00000152495 ENSG00000139515 ENSG00000146648 PMC4444223__F1 Model diagram of tumor necrosis factor-alpha (TNFA) signaling ENSG00000168040 PMC9097379__F7 ROCK-ezrin signaling pathway mediates LPS-induced cytokine production in pulmonary alveolar epithelial cells ENSG00000125538 ENSG00000189403 ENSG00000172936 ENSG00000184216 PMC8362831__F1 Tumor Growth in the High Frequency Medulloblastoma Mouse Model Ptch1+/−/Tis21KO Has a Specific Activation Signature of the PI3K/AKT/mTOR Pathway and Is Counteracted by the PI3K Inhibitor MEN1611 ENSG00000170962 ENSG00000291971 ENSG00000198793 ENSG00000155792 ENSG00000170145 ENSG00000155876 ENSG00000157106 ENSG00000121966 ENSG00000107581 PMC7828713__F1 Effectors of microglia function associated with neurodegeneration and how microglia damage or kills neurons ENSG00000197386 ENSG00000147894 PMC6315857__F1 Transforming growth factorB 1 (TGFB1) mediates a signaling pathway in tissue fibrosis ENSG00000149311 ENSG00000175054 ENSG00000198793 ENSG00000175104 PMC5696728__F2 Oncolytic virus mediated enhanced anti-tumoral immunity, including enhanced CAR T-cell recruitment and effector function ENSG00000123685 ENSG00000169245 ENSG00000164430 ENSG00000111537 ENSG00000138755 ENSG00000277943 ENSG00000026103 PMC5662566__F3 Integrin-linked kinase (ILK) signaling pathway is altered following RVFV infection ENSG00000196531 ENSG00000111057 ENSG00000138795 ENSG00000071051 ENSG00000148484 ENSG00000089159 PMC9483736__F8 Metabolomic and transcriptomic study to understand changes in metabolic and immune responses in steers under heat stress ENSG00000023445 ENSG00000163464 ENSG00000138193 ENSG00000041982 ENSG00000139567 ENSG00000198793 ENSG00000169429 ENSG00000124181 ENSG00000168610 PMC5765116__F9 DENV2-induced autophagy is ER stress-UPR dependent, involving PERK-eIF2Alpha-ATF4 and IRE1Alpha-JNK-BECN1 pathways ENSG00000128272 ENSG00000144895 ENSG00000145782 PMC3774329__F6 The interactions between Rho/Rho-kinase signaling and bone morphogenetic protein (BMP)/transforming growth factor (TGF)B signaling ENSG00000159224 ENSG00000163914 ENSG00000168938 PMC5025790__F9 Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency ENSG00000170365 ENSG00000261371 ENSG00000241186 ENSG00000156574 ENSG00000168036 PMC7890422__F1 Caveolin-1, a master regulator of cellular senescence ENSG00000163914 ENSG00000189403 ENSG00000185591 ENSG00000096717 ENSG00000146648 PMC9270398__F9 Working model of TRIM24 in regulation of P-bodies in response to insulin ENSG00000169047 ENSG00000122779 ENSG00000123908 PMC4297187__F2 Schematic summary of the results obtained from the microarray analysis ENSG00000004975 ENSG00000163637 ENSG00000156076 ENSG00000281324 ENSG00000162337 ENSG00000173218 ENSG00000175592 ENSG00000150764 ENSG00000213977 ENSG00000106483 ENSG00000104332 ENSG00000175029 ENSG00000106829 ENSG00000157240 ENSG00000164736 ENSG00000050165 ENSG00000146122 ENSG00000168646 ENSG00000155760 PMC9174896__F2 Bone Morphogenetic Protein Signaling in Cancer; Some Topics in the Recent 10 Years ENSG00000138166 ENSG00000134982 ENSG00000138071 PMC2757940__F2 Major components of FGF and HH signaling pathways ENSG00000128602 PMC5797063__F1 MicroRNA expression and activity in T-cell acute lymphoblastic leukemia ENSG00000148400 ENSG00000198435 ENSG00000109670 PMC7448411__F1 Wnt/Beta-catenin signaling by miRNAs ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000170558 ENSG00000165879 ENSG00000104332 ENSG00000168610 PMC7448411__F2 Use of miRNAs to combat EMT ENSG00000183734 PMC3541304__F1 Protective autophagy induced by RBX1/ROC1 knockdown or CRL inactivation via modulating the DEPTOR-MTOR axis ENSG00000168209 ENSG00000198793 ENSG00000155792 ENSG00000124762 PMC3106338__F10 INTERFERON-ALPHA MEDIATES THE DEVELOPMENT OF AUTOIMMUNITY BOTH BY DIRECT TISSUE TOXICITY AND THROUGH IMMUNE-CELL RECRUITMENT MECHANISMS ENSG00000132109 ENSG00000169245 ENSG00000042832 ENSG00000089127 ENSG00000134982 ENSG00000165409 PMC6851267__F8 Ghrelin attenuates neuroinflammation and demyelination in EAE involving the NLRP3 inflammasome signaling pathway and pyroptosis ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC10952045__F4 Various molecular mechanism of the osteogenic and osteoclastogenic function through cellular uptake of GNPs and functionalized GNPs ENSG00000170909 ENSG00000099985 ENSG00000214285 ENSG00000131196 PMC9636824__F9 Loss of Brca1 and Trp53 in adult mouse mammary ductal epithelium results in development of hormone receptor-positive or hormone receptor-negative tumors, depending on inactivation of Rb family proteins ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 ENSG00000139687 PMC7484401__F4 ANM analysis on long-term PIMi treated cells finds changes in protein complex enriched for signaling and growth pathways ENSG00000104856 ENSG00000153094 ENSG00000181104 ENSG00000198793 ENSG00000134308 ENSG00000099860 ENSG00000118971 ENSG00000100485 ENSG00000112715 ENSG00000164305 ENSG00000124762 ENSG00000137801 ENSG00000142166 ENSG00000103811 ENSG00000100385 ENSG00000122025 ENSG00000213949 ENSG00000177595 ENSG00000136997 ENSG00000166501 ENSG00000056558 ENSG00000105810 ENSG00000140443 ENSG00000023445 ENSG00000104689 ENSG00000168209 ENSG00000109320 ENSG00000027697 ENSG00000025039 ENSG00000234829 ENSG00000291420 ENSG00000187840 ENSG00000149311 ENSG00000138378 ENSG00000118503 ENSG00000177606 ENSG00000140285 ENSG00000162692 ENSG00000171608 PMC2572865__F1 Hematopoietic niche and bone meet ENSG00000107779 ENSG00000152266 ENSG00000162337 ENSG00000168036 PMC5726441__F4 PI3K pathway in human disease PMC5726441__F1 PI3K pathway in human disease ENSG00000124102 ENSG00000109452 ENSG00000163914 ENSG00000166278 ENSG00000113263 ENSG00000135605 ENSG00000010671 PMC5726441__F6 PI3K pathway in human disease ENSG00000002330 ENSG00000291971 ENSG00000169047 ENSG00000136997 ENSG00000137193 ENSG00000118515 PMC3164321__F1 KEAP1 Cullin-3 E3-ubiquitin ligase complex and its roles in maintaining cellular levels of NRF2 and IKBKB ENSG00000104365 ENSG00000100387 ENSG00000079999 PMC8235118__F8 Mitochondrial Function Are Disturbed in the Presence of the Anticancer Drug, 3-Bromopyruvate PMC6622839__F9 Model of VAMP3- and VAMP7-dependent surface transport ENSG00000292366 PMC9255244__F3 Fusobacterium nucleatum: a new player in regulation of cancer development and therapeutic response ENSG00000023445 ENSG00000274619 ENSG00000172936 ENSG00000136869 PMC7816800__F4 Functional interactions between genes under positive selection in the insulin signaling pathway (ingenuity pathway analysis, IPA) ENSG00000131473 ENSG00000002330 ENSG00000110395 ENSG00000106070 ENSG00000220205 ENSG00000079435 PMC7816800__F5 Functional interactions between genes under positive selection in the SIRT signaling pathway (ingenuity pathway analysis, IPA) ENSG00000165392 ENSG00000173039 PMC7816800__F6 Functional interactions between genes under positive selection in the NF-ĸB signaling pathway (ingenuity pathway analysis, IPA) ENSG00000104856 ENSG00000226275 ENSG00000102871 ENSG00000138798 ENSG00000196591 ENSG00000150455 PMC7816800__F7 Functional interactions between genes under positive selection in the mTOR signaling pathway (ingenuity pathway analysis, IPA) ENSG00000163435 ENSG00000171105 ENSG00000169047 ENSG00000198793 ENSG00000163914 ENSG00000173599 PMC7369834__F1 Genomic and non-genomic effects of glucocorticoid receptor (GR) binding to the different players of the inflammatory and metabolic pathways involved in the Duchenne muscular dystrophy (DMD) myocyte ENSG00000169047 ENSG00000198793 ENSG00000198947 PMC8020906__F2 mTOR is activated by growth factors via PI3K-Akt and RAS/MAPK pathways PMC11853774__F1 Crosstalk between the Hedgehog (Hh) and PI3K pathways in hematological malignancies ENSG00000122025 ENSG00000198793 ENSG00000128602 PMC5290741__F5 Immune Signature of Enhanced Functional Avidity CD8+ T Cells in vivo Induced by Vaccinia Vectored Vaccine ENSG00000174125 ENSG00000117020 ENSG00000198793 ENSG00000172936 PMC8827382__F2 p53 Modulation of Autophagy Signaling in Cancer Therapies: Perspectives Mechanism and Therapeutic Targets ENSG00000177169 ENSG00000152348 ENSG00000110497 ENSG00000198382 ENSG00000083290 ENSG00000126775 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC8827382__F1 p53 Modulation of Autophagy Signaling in Cancer Therapies: Perspectives Mechanism and Therapeutic Targets ENSG00000198793 ENSG00000171791 ENSG00000168040 PMC4472234__F4 Elementary Flux Mode Analysis Revealed Cyclization Pathway as a Powerful Way for NADPH Regeneration of Central Carbon Metabolism ENSG00000157404 ENSG00000197713 ENSG00000096088 ENSG00000150787 ENSG00000062485 PMC7335672__F9 miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells ENSG00000283887 ENSG00000226275 ENSG00000160013 ENSG00000168229 ENSG00000124212 PMC8020906__F5 Interplay between HBP, mTOR, and AMPK signaling pathways ENSG00000104812 ENSG00000177169 ENSG00000147162 ENSG00000111713 PMC8020906__F3 mTOR in cancer stem cells (CSCs) ENSG00000168036 PMC8020906__F4 AMPK pathway activation and energy homeostasis ENSG00000104812 ENSG00000177169 ENSG00000113161 ENSG00000110931 ENSG00000265972 PMC8469128__F1 MicroRNAs—The Heart of Post-Myocardial Infarction Remodeling ENSG00000140564 ENSG00000185591 PMC7929927__F8 BPIFB3 interacts with ARFGAP1 and TMED9 to regulate non-canonical autophagy and RNA virus infection ENSG00000184840 PMC8469128__F2 MicroRNAs—The Heart of Post-Myocardial Infarction Remodeling ENSG00000164056 ENSG00000198793 ENSG00000122877 ENSG00000108821 ENSG00000175104 PMC5404743__F1 New Milestones Ahead in Complement-Targeted Therapy ENSG00000105664 ENSG00000117322 ENSG00000062485 PMC7401802__F1 Biosynthesis of CL and PE ENSG00000169230 ENSG00000284009 ENSG00000087157 ENSG00000173599 ENSG00000198670 ENSG00000026652 ENSG00000184207 ENSG00000241878 ENSG00000237834 ENSG00000110536 PMC4933442__F8 TNF-Alpha-induced expression of the inflammation-associated genes mediated by PLCE ENSG00000108691 ENSG00000163739 ENSG00000169429 ENSG00000198670 PMC1905845__F1 Schematic representation showing the plausible signaling events from uPAR integrin complex ENSG00000002330 ENSG00000198793 ENSG00000168040 ENSG00000122194 ENSG00000026103 PMC2662295__F5 TRAF6- and MEKK1-mediated signal for IFNB production in the RLH/IPS-1 signaling pathway ENSG00000131323 ENSG00000168040 ENSG00000175104 PMC8160027__F2 Vital role for nitric oxide in intraocular pressure homeostasis ENSG00000163072 ENSG00000124181 ENSG00000142546 PMC8160027__F3 Vital role for nitric oxide in intraocular pressure homeostasis ENSG00000261371 ENSG00000291971 ENSG00000168036 ENSG00000103335 PMC2905744__F3 Novel targets for the treatment and palliation of gastrointestinal neuroendocrine tumors ENSG00000002330 ENSG00000198793 PMC3826168__F2 Molecular mechanism and function of CD40/CD40L engagement in the immune system ENSG00000131323 ENSG00000127191 PMC3013016__F8 The molecular mechanisms employed by the Ras/MAPK pathway to regulate mTORC1 signaling PMC8534692__F7 Hormonally Induced Hepatocellular Carcinoma in Diabetic Wild Type and Carbohydrate Responsive Element Binding Protein Knockout Mice ENSG00000057252 ENSG00000111058 ENSG00000160883 ENSG00000166391 ENSG00000172497 ENSG00000109929 ENSG00000141458 ENSG00000052802 PMC6411465__F9 A schematic diagram illustrating the proposed mechanism of AR‐CD44‐SOX2 signaling ENSG00000026508 PMC7759768__F3 Major sources of oxidative stress in Parkinson’s disease and the corresponding antioxidant defense mechanism in dopaminergic neurons ENSG00000132906 ENSG00000002330 ENSG00000131095 ENSG00000164305 PMC9139943__F3 Clinical Landscape of PARP Inhibitors in Ovarian Cancer: Molecular Mechanisms and Clues to Overcome Resistance ENSG00000175054 ENSG00000138385 PMC8842882__F1 Signaling networks orchestrate metabolism for coordination of T cell fate ENSG00000156127 ENSG00000136997 ENSG00000137265 PMC11049012__F1 BCG-driven activation of the bladder cancer TME involves the NFKB/TNFA signaling pathway and IRFs/IFN pathway ENSG00000169248 ENSG00000169245 ENSG00000102962 ENSG00000107562 ENSG00000138755 ENSG00000169429 PMC9139943__F4 Clinical Landscape of PARP Inhibitors in Ovarian Cancer: Molecular Mechanisms and Clues to Overcome Resistance ENSG00000012048 ENSG00000051180 ENSG00000205250 PMC9139943__F6 Clinical Landscape of PARP Inhibitors in Ovarian Cancer: Molecular Mechanisms and Clues to Overcome Resistance ENSG00000083093 ENSG00000172716 ENSG00000227345 ENSG00000138385 PMC7956519__F2 Main non-canonical signaling pathways activated by JAK2V617F in Ph-negative MPNs ENSG00000172936 ENSG00000187266 ENSG00000150455 ENSG00000187244 ENSG00000175104 PMC7956519__F3 Major non-canonical mechanisms derived from CALRMut ENSG00000151702 ENSG00000153944 ENSG00000134982 ENSG00000232326 ENSG00000231925 ENSG00000164830 PMC4178743__F7 Interference in type I IFN production by HEV proteins ENSG00000088888 ENSG00000121060 PMC11737358__F2 Metabolic pathway of homoarginine (hArg) synthesis and associated substrates ENSG00000173930 ENSG00000118520 ENSG00000036473 PMC99537__F5 Basic metabolic pathways in C ENSG00000182511 ENSG00000112964 ENSG00000150787 PMC3244200__F4 Epithelial–mesenchymal transition (EMT)-related pathways ENSG00000138798 ENSG00000177606 ENSG00000164690 ENSG00000146648 PMC6099423__F1 Model about the effect of indoleamine 2,3-dioxygenase 1 (IDO1) on the utilization of the main energy sources by activated CD4+ T-cells ENSG00000134982 ENSG00000106546 PMC6028720__F3 Compound–target–pathway subnetwork of 12 compounds relating to AD ENSG00000143799 ENSG00000114200 ENSG00000110921 ENSG00000178999 ENSG00000103222 ENSG00000255974 ENSG00000148344 ENSG00000171791 ENSG00000142082 ENSG00000118777 ENSG00000196396 ENSG00000274542 ENSG00000149295 ENSG00000112312 ENSG00000277571 ENSG00000184845 ENSG00000117525 ENSG00000239732 ENSG00000095303 ENSG00000123374 ENSG00000165646 ENSG00000104321 ENSG00000108786 ENSG00000161905 ENSG00000116044 ENSG00000086991 ENSG00000164985 ENSG00000170425 ENSG00000164120 ENSG00000073756 ENSG00000102967 ENSG00000138160 ENSG00000283100 ENSG00000061938 ENSG00000274247 ENSG00000176208 ENSG00000152904 ENSG00000103546 ENSG00000107854 ENSG00000255398 ENSG00000148680 ENSG00000149554 ENSG00000074410 ENSG00000146648 ENSG00000173273 ENSG00000262243 ENSG00000122008 PMC7118423__F2 The angiotensin-converting enzyme 2 (ACE2) signalling pathway involved in SARS-CoV-induced CCL2 expression ENSG00000108691 ENSG00000130234 PMC7864727__F1 Epigenetic Regulation and Nonepigenetic Mechanisms of Ferroptosis Drive Emerging Nanotherapeutics in Tumor ENSG00000182511 ENSG00000197635 ENSG00000115107 PMC3666381__F1 Metabolism in totipotent stem cells ENSG00000173599 ENSG00000084774 PMC3666381__F2 Metabolism in pluripotent stem cells ENSG00000178445 PMC5852605__F1 Canonical and non-canonical Wnt pathways and their effects in pluripotent stem cells (PSCs) ENSG00000134982 ENSG00000163914 PMC11889860__F5 Apium graveolens-associated Aspergillus sp.: metabolomic profiling and anti-MRSA potential supported by in silico studies ENSG00000213928 ENSG00000239732 ENSG00000105397 ENSG00000170458 ENSG00000172936 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000143387 PMC11889860__F6 Apium graveolens-associated Aspergillus sp.: metabolomic profiling and anti-MRSA potential supported by in silico studies ENSG00000167207 ENSG00000110448 ENSG00000102871 ENSG00000007908 ENSG00000168040 ENSG00000166278 ENSG00000164305 ENSG00000169245 ENSG00000149968 ENSG00000177606 ENSG00000164136 ENSG00000128342 ENSG00000083799 ENSG00000168404 PMC3965173__F1 Signaling pathways that can be inhibited to increase the radiation response of tumors ENSG00000002330 ENSG00000198793 ENSG00000146648 PMC8941656__F1 Evaluation of Iron Deficiency and Iron Overload ENSG00000010704 ENSG00000106327 PMC5287922__F2 Lessons Learned From Trials Targeting Cytokine Pathways in Patients With Inflammatory Bowel Diseases ENSG00000162594 ENSG00000096996 PMC1237009__F1 Will the Real Cholesterol Transporter Please Stand Up ENSG00000138075 ENSG00000042832 ENSG00000143761 ENSG00000015520 ENSG00000120437 ENSG00000143921 PMC11049059__F8 CCN1-mediated signaling pathway in pregnant women with SARS-CoV-2-infection PMC7483921__F7 Inhibition of Wnt/Beta-catenin signaling by TcdA ENSG00000154342 ENSG00000108582 ENSG00000134982 ENSG00000168036 PMC8145791__F14 TRPC channel-derived calcium fluxes differentially regulate ATP and flow–induced activation of eNOS ENSG00000133107 ENSG00000293604 ENSG00000138741 PMC5086093__F7 Models depicting consequences of PNH-related mutations on NEDD4L stability and PI3K/Akt/mTOR and TGFB/Smad pathways ENSG00000166278 ENSG00000173406 PMC2829061__F7 Cdk1 Targets Srs2 to Complete Synthesis-Dependent Strand Annealing and to Promote Recombinational Repair ENSG00000051180 ENSG00000177045 PMC7452853__F11 Proposed mechanisms associated with 10% XCDM-induced hTM cell stiffening and Wnt pathway activation-mediated rescue of cells from stiffening ENSG00000281324 ENSG00000162337 ENSG00000177469 ENSG00000026508 ENSG00000168036 ENSG00000168646 PMC8504146__F5 Non‐coding RNAs in drug resistance of oral squamous cell carcinoma and therapeutic potential PMC12254798__F1 Obese adipose tissue (AT) microenvironment interacts with tumor cells during cancer progression ENSG00000162711 ENSG00000168610 PMC8504146__F2 Non‐coding RNAs in drug resistance of oral squamous cell carcinoma and therapeutic potential ENSG00000167601 ENSG00000170558 ENSG00000146648 PMC11356869__F1 Signaling pathways in osteogenesis and osteoclastogenesis ENSG00000170365 ENSG00000168036 ENSG00000175104 ENSG00000131196 ENSG00000143387 PMC11356869__F2 East Asian Herbal Medicine (EAHM) effect on bone to prevent osteoporosis ENSG00000149968 ENSG00000168036 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC8536789__AF1 Fatty Acids Inhibit LAMP2-Mediated Autophagy Flux via Activating ER Stress Pathway in Alcohol-Related Liver Disease ENSG00000128272 ENSG00000005893 ENSG00000285482 PMC7886759__F3 Lipotoxic UPR induces hepatic cell death ENSG00000144895 ENSG00000171791 ENSG00000162772 ENSG00000127191 PMC10141502__F1 Nutrigenomic profiling of reduced specification diets and phytogenic inclusion effects on critical toll-like receptor signaling, mitogen-activated protein kinase-apoptosis, and PI3K-Akt-mTOR gene components along the broiler gut ENSG00000226275 ENSG00000172936 ENSG00000136869 ENSG00000213341 ENSG00000175104 ENSG00000189067 ENSG00000164342 ENSG00000026103 PMC7886759__F4 Modes of cell death in NASH ENSG00000278718 ENSG00000162711 ENSG00000168404 ENSG00000026103 PMC6102695__F7 Kyoto Encyclopedia of Genes and Genomes pathway map illustrating ‘hsa05200: Pathways in cancer’, as identified by pathway enrichment analysis using the Database for Annotation, Visualization and Integrated Discovery ENSG00000002330 ENSG00000084110 PMC6500972__F8 Poly(ADP‐ribosyl)ation of BRD7 by PARP1 confers resistance to DNA‐damaging chemotherapeutic agents ENSG00000143799 ENSG00000118518 ENSG00000166164 PMC3210466__F1 MTOR signaling pathways ENSG00000198793 ENSG00000164327 PMC4991447__F9 Bufalin suppresses hepatocellular carcinoma invasion and metastasis by targeting HIF-1A via the PI3K/AKT/mTOR pathway ENSG00000170558 ENSG00000198793 PMC7986493__F10 Glycine, serine, and threonine metabolism pathways of L ENSG00000092621 ENSG00000172482 ENSG00000135069 ENSG00000146733 PMC3370224__F9 The ARF6 signaling pathway involved in HLHCGR internalization as deduced from the present study ENSG00000138039 ENSG00000165527 PMC5357501__F4 The significance of SIRT1 in Alzheimer’s disease ENSG00000142192 ENSG00000096717 ENSG00000137845 PMC5038066__F7 Proposed model for Leishmania donovani-mediated host TLR2 downstream signaling ENSG00000174125 PMC4484471__F8 Metastasis-associated in colon cancer-1 promotes vasculogenic mimicry in gastric cancer by upregulating TWIST1/2 ENSG00000019991 ENSG00000122691 ENSG00000145321 ENSG00000183742 PMC7809420__F5 Differentially expressed lncRNAs in liver tissues of TX mice with hepatolenticular degeneration ENSG00000186212 ENSG00000051523 ENSG00000121207 ENSG00000136141 ENSG00000153815 ENSG00000186532 ENSG00000134533 ENSG00000101000 ENSG00000137845 ENSG00000157227 ENSG00000158825 ENSG00000113790 ENSG00000125266 ENSG00000143878 ENSG00000105697 ENSG00000173083 ENSG00000116741 ENSG00000166183 ENSG00000257335 ENSG00000066468 ENSG00000100422 ENSG00000063660 ENSG00000177606 ENSG00000172005 ENSG00000139517 ENSG00000164107 ENSG00000088298 ENSG00000105426 ENSG00000228594 ENSG00000138080 ENSG00000137675 ENSG00000136940 ENSG00000164949 ENSG00000101608 PMC6305110__F1 Promising immune checkpoint LAG-3: from tumor microenvironment to cancer immunotherapy ENSG00000114455 ENSG00000089692 PMC8169545__F2 Novel ligands and modulators of triggering receptor expressed on myeloid cells receptor family: 2015–2020 updates ENSG00000137845 PMC5489658__F8 Schematic summary of the mechanisms by which tick-borne Phlebovirus NSs proteins inhibit the canonical IFN induction and signaling pathways ENSG00000183735 ENSG00000159128 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000185436 ENSG00000027697 ENSG00000142166 PMC4399027__F2 Activation of the MAPK pathway in thyroid cancer ENSG00000047410 ENSG00000157764 PMC6302542__F3 Leptin regulates fatty acid oxidation in muscle by activating AMPK ENSG00000115138 ENSG00000166603 PMC3068086__F5 Coordinately up-regulated cell cycle genes in CD8+ T cells from the VIR group (VIR versus BDL) illustrated in cell cycle pathway from Kyoto Encyclopedia of Genes and Genomes (KEGG; http://www.genome.jp/kegg/) ENSG00000132646 ENSG00000123374 ENSG00000277273 PMC3068086__F6 Branches of MAPK pathway significantly enriched in CD4+ T cells from the LTNP group (BDL versus LTNP) ENSG00000005339 ENSG00000070831 ENSG00000100906 ENSG00000050748 ENSG00000177606 PMC4012993__F6 Epithelial SCAP/INSIG/SREBP Signaling Regulates Multiple Biological Processes during Perinatal Lung Maturation ENSG00000162552 ENSG00000154764 ENSG00000156076 ENSG00000134982 ENSG00000291971 ENSG00000181104 ENSG00000168036 ENSG00000196628 ENSG00000157240 ENSG00000157500 ENSG00000117020 ENSG00000177606 ENSG00000050165 ENSG00000165879 ENSG00000076641 ENSG00000168646 PMC7037284__F1 Guanylyl cyclase-cGMP signaling pathway ENSG00000173786 ENSG00000096088 ENSG00000214285 PMC6028303__F2 Revisiting antipsychotic drug actions through gene networks associated with schizophrenia ENSG00000105894 ENSG00000117020 ENSG00000140564 ENSG00000110492 ENSG00000130287 ENSG00000156603 ENSG00000081189 ENSG00000126458 ENSG00000196628 ENSG00000198911 ENSG00000149295 PMC9130392__F1 mTOR pathway gene expression in association with race and clinicopathological characteristics in Black and White breast cancer patients PMC9406168__F6 Integrative, In Silico and Comparative Analysis of Breast Cancer Secretome Highlights Invasive-Ductal-Carcinoma-Grade Progression Biomarkers ENSG00000049323 ENSG00000142798 ENSG00000058085 ENSG00000130702 ENSG00000198793 ENSG00000168036 ENSG00000150093 ENSG00000112715 ENSG00000166147 ENSG00000172037 ENSG00000137801 ENSG00000170365 ENSG00000130164 ENSG00000108679 ENSG00000188157 ENSG00000136997 ENSG00000185591 ENSG00000155760 ENSG00000169174 ENSG00000173402 ENSG00000168610 ENSG00000291420 ENSG00000183734 ENSG00000134013 ENSG00000063660 ENSG00000146648 ENSG00000082212 PMC3068086__F7 Schematic overview of the network of enriched pathways related to HIV disease progression ENSG00000002330 ENSG00000164305 PMC5315647__F7 Hormonal Regulation of the Repair of UV Photoproducts in Melanocytes by the Melanocortin Signaling Axis ENSG00000175054 ENSG00000115138 ENSG00000136936 PMC3068086__F4 Coordinately up-regulated TCA cycle genes in CD8+ T cells from the VIR group (VIR versus LTNP) illustrated in TCA cycle pathway from Kyoto Encyclopedia of Genes and Genomes (KEGG; http://www.genome.jp/kegg/) ENSG00000131473 ENSG00000143252 ENSG00000168803 ENSG00000105953 ENSG00000172340 ENSG00000146701 PMC8251939__SF4 Design and Synthesis of New Withaferin A Inspired Hedgehog Pathway Inhibitors ENSG00000144857 PMC5315647__F9 Hormonal Regulation of the Repair of UV Photoproducts in Melanocytes by the Melanocortin Signaling Axis ENSG00000175054 ENSG00000101440 ENSG00000136936 PMC5587765__F3 IPA canonical pathway analysis and molecular activity of genes regulated by p53 in response to OT in differentiated SH-SY5Y cells ENSG00000132906 ENSG00000110330 ENSG00000002330 ENSG00000116717 ENSG00000197442 ENSG00000067900 ENSG00000100033 ENSG00000164305 ENSG00000115317 ENSG00000160049 ENSG00000180447 ENSG00000120868 ENSG00000064012 ENSG00000125968 ENSG00000026103 PMC7720404__F1 TF-miRNA-gene network ENSG00000177300 ENSG00000115904 ENSG00000134873 ENSG00000088256 ENSG00000113946 ENSG00000187764 ENSG00000174021 ENSG00000123552 ENSG00000242616 ENSG00000103479 ENSG00000159216 ENSG00000166501 ENSG00000101333 ENSG00000282899 ENSG00000158050 ENSG00000149564 ENSG00000259207 ENSG00000183072 ENSG00000114030 ENSG00000106299 ENSG00000178363 ENSG00000143933 ENSG00000137841 ENSG00000168610 ENSG00000132170 ENSG00000221823 ENSG00000125820 ENSG00000117020 ENSG00000173757 ENSG00000130669 ENSG00000175305 PMC1781924__F1 Thy-1-associated signaling pathways ENSG00000124102 ENSG00000170365 ENSG00000213658 ENSG00000010810 ENSG00000168610 ENSG00000154096 PMC8505958__F2 Abnormal Airway Mucus Secretion Induced by Virus Infection ENSG00000163235 ENSG00000125538 ENSG00000185591 ENSG00000168610 ENSG00000146648 ENSG00000196689 ENSG00000106546 PMC10606123__F1 Underlying mechanism of histone deacetylases in regulating ovarian cancer metastasis ENSG00000094631 ENSG00000171720 ENSG00000168036 ENSG00000048052 ENSG00000189403 ENSG00000129514 ENSG00000096717 ENSG00000142082 ENSG00000136826 ENSG00000108840 PMC4693276__F4 The synthetic lethality pathway model based on a deficiency in Alt-NHEJ and the double-strand break repair pathway ENSG00000012048 ENSG00000177084 ENSG00000139618 PMC3943304__F5 Activation of growth factor receptor protein tyrosine kinases results in autophosphorylation on tyrosine residues ENSG00000002330 PMC7288517__F6 Mechanisms of accelerated aging triggering PD ENSG00000049768 ENSG00000170340 PMC3943304__F6 Canonical and non-canonical JAK-STAT pathway and its subversion by BCR-ABL or mutant KIT ENSG00000157404 ENSG00000033327 ENSG00000291971 ENSG00000198793 PMC7288517__F5 Shortest paths for enrichment analysis of KEGG and BP ENSG00000096996 ENSG00000164398 ENSG00000049768 ENSG00000170340 PMC9659971__F2 Immunometabolism in the tumor microenvironment and its related research progress ENSG00000136997 ENSG00000141526 ENSG00000183484 PMC9659971__F3 Immunometabolism in the tumor microenvironment and its related research progress ENSG00000135218 ENSG00000169710 ENSG00000124253 ENSG00000089163 ENSG00000285379 PMC4630370__F8 Proposed mechanism for NFKB signaling inhibition mediated by the antitumor peptide CIGB-552 ENSG00000166167 ENSG00000173163 ENSG00000078747 ENSG00000113558 ENSG00000175104 ENSG00000135341 ENSG00000145391 PMC4931624__F1 The Wnt signaling pathway and possible points for therapeutic interventions to restrict S100A4-mediated tumor progression and metastasis ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000196154 ENSG00000168036 PMC9708673__F1 Pathway-level mutation analysis in primary high-grade serous ovarian cancer and matched brain metastases ENSG00000110799 ENSG00000134982 ENSG00000169884 ENSG00000164327 ENSG00000141564 ENSG00000134760 ENSG00000177201 ENSG00000128394 ENSG00000109111 ENSG00000102001 ENSG00000101868 ENSG00000181074 ENSG00000141867 ENSG00000169436 ENSG00000196862 ENSG00000010322 ENSG00000177182 ENSG00000292140 ENSG00000090615 ENSG00000197943 ENSG00000136869 ENSG00000138768 ENSG00000100219 ENSG00000277401 ENSG00000140443 ENSG00000142192 ENSG00000160145 ENSG00000133056 ENSG00000100345 ENSG00000116675 ENSG00000197694 ENSG00000139618 ENSG00000138735 ENSG00000145794 ENSG00000135605 ENSG00000065989 ENSG00000145147 ENSG00000198793 ENSG00000172572 ENSG00000149782 ENSG00000122194 ENSG00000038382 ENSG00000125810 ENSG00000108055 ENSG00000088305 ENSG00000089041 ENSG00000105639 ENSG00000168610 ENSG00000115896 ENSG00000149311 ENSG00000120899 ENSG00000292130 ENSG00000122705 ENSG00000164690 ENSG00000115232 ENSG00000141367 ENSG00000198625 PMC5356908__F2 Immune cells in liver regeneration ENSG00000172936 ENSG00000168610 PMC4969639__F7 Proposed model for IFNGamma-induced apoptosis of HNSCC cells ENSG00000132906 ENSG00000111537 ENSG00000196954 ENSG00000164305 PMC7139641__F3 Network of the most strongly dysregulated proteins of the glomerular ECM in FSGS PMC8833116__F10 Overexpression of chaperonin containing TCP1 subunit 7 has diagnostic and prognostic value for hepatocellular carcinoma ENSG00000081051 ENSG00000135624 PMC5160413__F1 RA pathway is differentially regulated in stem cells from VS and SC fat depots ENSG00000184254 ENSG00000121039 ENSG00000128918 ENSG00000162496 ENSG00000104368 ENSG00000143387 ENSG00000117525 ENSG00000136960 ENSG00000041982 ENSG00000197576 ENSG00000175745 ENSG00000196549 ENSG00000095303 ENSG00000111341 ENSG00000113361 ENSG00000118849 ENSG00000164093 ENSG00000143995 PMC6022997__F3 Illustration showing presumed mechanisms mediating suberoylanilide hydroxamic acid (SAHA)-induced autophagy ENSG00000177169 ENSG00000002330 ENSG00000198793 ENSG00000171791 ENSG00000078237 PMC6954088__F8 The proposed mechanism for AAV9-shMyh9 against I/R-induced neuronal injury ENSG00000067900 PMC3786590__F1 Simple molecular pathway for sex determination in the mammalian gonads ENSG00000169218 ENSG00000104899 ENSG00000125398 ENSG00000168066 ENSG00000134363 ENSG00000139549 ENSG00000102678 PMC6172149__F1 Pathogen interactions with endothelial cells and the induction of innate and adaptive immunity ENSG00000169248 ENSG00000169245 ENSG00000003436 ENSG00000088888 ENSG00000138755 PMC3684179__F1 Cyclin D1 stability is regulated by ubiquitination-dependent proteasomal degradation ENSG00000174989 ENSG00000036672 PMC6022997__F1 Autophagy, apoptosis, and cell cycle arrest mediated by the activity of nuclear p53 protein (p53) in its function as a transcription factor in stress conditions ENSG00000177169 ENSG00000002330 ENSG00000198793 ENSG00000171791 ENSG00000057663 PMC6022997__F2 Autophagy and apoptosis mediated by the cytoplasmic activity of p53 protein under basal conditions ENSG00000177169 ENSG00000002330 ENSG00000198793 ENSG00000171791 ENSG00000078237 PMC3247643__F6 Overlay of significant canonical pathway and the connectivity in the molecular mechanism of cancer, with the eight genes in IPA canonical pathway and with the genes in Network (I) that differentially altered in PCB exposure ENSG00000110944 ENSG00000135218 ENSG00000105329 ENSG00000058085 ENSG00000153094 ENSG00000150093 ENSG00000132478 ENSG00000049860 ENSG00000171791 ENSG00000118971 ENSG00000128268 ENSG00000288411 ENSG00000130164 ENSG00000005421 ENSG00000117335 ENSG00000133740 ENSG00000006327 ENSG00000256646 ENSG00000115461 PMC3618688__F4 Resection of Non-Small Cell Lung Cancers Reverses Tumor-Induced Gene Expression Changes in the Peripheral Immune System ENSG00000174123 ENSG00000104856 ENSG00000174125 ENSG00000239732 ENSG00000170458 ENSG00000109320 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000162924 ENSG00000150455 ENSG00000175104 PMC6794464__F2 Scheme of differentiation of M cells in PP ENSG00000104856 ENSG00000175130 ENSG00000185215 ENSG00000005513 ENSG00000173039 ENSG00000269404 ENSG00000175104 ENSG00000115009 PMC3786590__F3 Neuroendocrine control of pituitary and gonadal function ENSG00000109163 ENSG00000198576 ENSG00000170498 ENSG00000116014 PMC8117355__F1 Apoptosis-Related Long Non-coding RNAs in Ovarian Cancer ENSG00000143799 ENSG00000168283 ENSG00000198901 ENSG00000134086 ENSG00000110395 ENSG00000115415 ENSG00000159388 ENSG00000205250 ENSG00000124762 ENSG00000165795 ENSG00000026103 PMC9055624__F2 Twenty years of progress in angiotensin converting enzyme 2 and its link to SARS-CoV-2 disease ENSG00000291971 ENSG00000130234 ENSG00000138798 ENSG00000137841 PMC3745819__F1 A CENTRAL ROLE FOR INDUCIBLE HEAT SHOCK PROTEIN 70 IN AUTOIMMUNE VITILIGO ENSG00000112149 PMC5059430__F9 EtOH-induced BK channel internalization via Wnt/Beta-catenin signaling ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC7863132__F2 Endoplasmic Reticulum Calcium Homeostasis in Kidney Disease ENSG00000156026 PMC4631624__F1 Homologous recombination deficiency: Exploiting the fundamental vulnerability of ovarian cancer ENSG00000149311 ENSG00000012048 ENSG00000083093 ENSG00000138346 ENSG00000144554 ENSG00000188827 ENSG00000187790 ENSG00000197299 ENSG00000051180 ENSG00000276787 ENSG00000139618 PMC7863132__F1 Endoplasmic Reticulum Calcium Homeostasis in Kidney Disease ENSG00000156026 PMC7570055__F2 Cigarette smoke-related vascular irritation and activation in patients with COPD ENSG00000169245 ENSG00000186810 ENSG00000081041 ENSG00000163235 ENSG00000125538 ENSG00000138755 ENSG00000196591 ENSG00000121807 PMC8537160__F1 Wnt and Beta-Catenin Signaling in the Bone Metastasis of Prostate Cancer ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000070831 ENSG00000134982 ENSG00000168036 PMC5385559__F5 Genetic dissection of seed oil and protein content and identification of networks associated with oil content in Brassica napus ENSG00000148798 PMC12034266__F1 Sphingolipid biosynthesis and metabolic pathways ENSG00000100422 ENSG00000143753 ENSG00000166224 ENSG00000119537 ENSG00000148154 PMC8630440__F4 Proteomic analysis of human umbilical cord serum exosomes using mass spectrometry and preliminary study of their biological activities in liver cancer cell lines ENSG00000136457 ENSG00000110799 ENSG00000026508 PMC4120074__F7 Function-blocking ERBB3 antibody inhibits the adaptive response to RAF inhibitor ENSG00000157764 ENSG00000065361 PMC8650380__F2 Gram-negative bacteria and their lipopolysaccharides in Alzheimer’s disease: pathologic roles and therapeutic implications ENSG00000091592 ENSG00000172936 ENSG00000136869 PMC8650380__F4 Gram-negative bacteria and their lipopolysaccharides in Alzheimer’s disease: pathologic roles and therapeutic implications ENSG00000197971 ENSG00000172936 ENSG00000136869 ENSG00000162692 PMC4120074__F2 Function-blocking ERBB3 antibody inhibits the adaptive response to RAF inhibitor ENSG00000157404 ENSG00000198793 ENSG00000164327 ENSG00000146648 ENSG00000105723 PMC6932173__F6 Proposed inositol-requiring protein 1 alpha (IRE1A)-dependent mechanism of type I interferon induction upon proteasome impairment ENSG00000144895 ENSG00000131323 ENSG00000276561 PMC11893557__F2 Impact of autogenous and post-intervention gut microbiota on immune cells in HCC ENSG00000169245 ENSG00000161921 ENSG00000198793 ENSG00000166090 PMC12196557__F5 Interactive effects of prenatal Poly I:C exposure and antipsychotics on various signaling pathways and receptors in the dorsal raphe nuclei ENSG00000117020 ENSG00000168036 ENSG00000164342 PMC12092528__F4 RhoA/ROCK signaling pathway and Tau ENSG00000163914 PMC8760698__F2 Bioactivities and mechanisms of natural medicines in the management of pulmonary arterial hypertension ENSG00000148400 ENSG00000136997 ENSG00000171759 ENSG00000171388 ENSG00000204217 PMC3038181__F1 Activation of the PI3K/Akt pathway in cancer ENSG00000155792 ENSG00000175104 ENSG00000146648 PMC3839612__F5 A detailed model of the Rad5-mediate template switch pathway, assuming gap filling dependent on a subset of HR functions after the replication fork has passed ENSG00000132646 ENSG00000070950 ENSG00000051180 ENSG00000178966 PMC8979958__F3 Mammalian sirtuins and metabolic reprogramming ENSG00000187531 ENSG00000124523 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000089163 ENSG00000115419 ENSG00000283100 PMC8760698__F5 Bioactivities and mechanisms of natural medicines in the management of pulmonary arterial hypertension ENSG00000162711 ENSG00000144895 ENSG00000198793 ENSG00000171759 ENSG00000189403 ENSG00000171791 PMC7779353__F10 Diagram of a signaling regulatory network that determines the AEC II differentiation phenotype ENSG00000130234 ENSG00000168036 PMC3657316__F3 Ciliary signaling pathways implicated in control of cell proliferation ENSG00000134853 ENSG00000123374 PMC3160786__F1 mTOR signaling pathway The scheme depicts mTOR signaling cascade in the regulation of energy and growth factor-dependent translation and autophagy ENSG00000177169 ENSG00000163435 ENSG00000155792 PMC3160786__F2 Amino acids sensing of mTORC1 Rag-Ragulator-dependent mTORC1 activation in response to amino acid PMC6641558__F3 The proposed pathway for constitutive AhR signaling and crosstalk with Src ENSG00000291971 ENSG00000106546 PMC7038996__F7 Two-step mechanism for SSB end resection in SSB repair and signaling.Step 1: An SSB is recognized by APE1, which then initiates SSB end resection in the 3′–5′ direction to generate a small gap (this work) ENSG00000175054 ENSG00000132646 ENSG00000138385 PMC4051134__F5 Targeting JAK2 in the therapy of myeloproliferative neoplasms ENSG00000137193 ENSG00000187266 ENSG00000292210 PMC6120446__F7 Comparison of gene expression profiles between human erythroid cells derived from fetal liver and adult peripheral blood ENSG00000177455 ENSG00000065833 ENSG00000002330 ENSG00000186716 ENSG00000198517 ENSG00000120885 ENSG00000116990 PMC3334621__F7 IsomiRs and miRNAs target similar biological pathways ENSG00000138795 ENSG00000002330 ENSG00000064393 ENSG00000168040 ENSG00000016082 ENSG00000099330 ENSG00000149311 ENSG00000175054 ENSG00000177606 ENSG00000102104 ENSG00000196712 ENSG00000132341 ENSG00000026103 PMC4051134__F3 Targeting JAK2 in the therapy of myeloproliferative neoplasms ENSG00000187266 PMC7721612__F9 RNA sequencing analyses reveal differentially expressed genes and pathways as Notch2 targets in B-cell lymphoma ENSG00000087095 ENSG00000284774 ENSG00000100906 ENSG00000291971 ENSG00000198793 ENSG00000116701 ENSG00000141564 ENSG00000127191 ENSG00000121879 ENSG00000120910 ENSG00000226275 ENSG00000010810 ENSG00000186716 ENSG00000177606 ENSG00000071051 ENSG00000131196 PMC6120446__F6 Comparison of gene expression profiles between human erythroid cells derived from fetal liver and adult peripheral blood ENSG00000087095 ENSG00000170458 ENSG00000117400 ENSG00000081189 ENSG00000132693 ENSG00000026103 PMC7086007__F1 Pathogenic mechanisms of CRP causing inflammation and renal fibrosis in diabetic nephropathyCRP binds to FcGRII and activates the NFKB signal pathway to induce inflammation ENSG00000198793 ENSG00000132693 PMC9321586__F3 Mechanistic Interrogation of Cell Transformation In Vitro: The Transformics Assay as an Exemplar of Oncotransformation ENSG00000162889 ENSG00000213928 ENSG00000141503 ENSG00000198793 ENSG00000169047 ENSG00000134070 ENSG00000157625 ENSG00000175104 PMC5668671__F2 Toll-like receptor signaling ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000164342 PMC7086007__F3 NLR signaling pathways in diabetic nephropathyThe NLRP3 inflammasome can be activated by the ROS/TXNIP/NADPH oxidase signaling pathway and extracellular ATP, and inhibited by IL-22 ENSG00000162711 ENSG00000167207 ENSG00000187796 ENSG00000125538 ENSG00000091106 ENSG00000265972 ENSG00000106100 PMC5668671__F5 HPVs infect host epithelial cells through TLRs ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC2639789__F9 Summary diagram of E2 regulation of Wnt/Beta-catenin signaling pathway after cerebral ischemia and proposed role in E2 ischemic neuroprotection ENSG00000177606 ENSG00000277641 PMC12134342__F3 Tumor-associated neutrophil oncogenic mechanisms ENSG00000143546 ENSG00000118785 ENSG00000169047 ENSG00000005381 ENSG00000196937 ENSG00000168610 PMC12134342__F4 Tumor-associated neutrophil tumoricidal mechanisms ENSG00000019991 ENSG00000081041 ENSG00000198053 ENSG00000005381 ENSG00000011478 ENSG00000026103 PMC3902172__F7 In vivo Mapping of Notch Pathway Activity in Normal and Stress Hematopoiesis ENSG00000178860 ENSG00000128917 ENSG00000148400 ENSG00000114315 PMC12134342__F5 Interactions of tumor-associated neutrophils with other cells in the tumor immune microenvironment ENSG00000081181 ENSG00000081041 ENSG00000110218 ENSG00000115594 ENSG00000277943 PMC6797988__F6 Inhibitory effect of glycyrrhizin on ferroptosis during acute liver failure functions by promoting the Nrf2/HO-1/HMGB1 signaling pathway ENSG00000167468 ENSG00000189403 PMC9445553__F6 Immune responses to different Uropathogens call individual interventions for bladder infection ENSG00000108691 ENSG00000081041 ENSG00000146648 ENSG00000115009 ENSG00000165799 PMC3225017__F2 c-MET signaling adaptors and mediators ENSG00000019991 ENSG00000110395 ENSG00000291971 ENSG00000168610 PMC3225017__F3 c-MET transactivation ENSG00000124102 ENSG00000019991 ENSG00000291971 ENSG00000026508 PMC8146627__F1 Interrelationship between pregnancy, venous thromboembolism, and thyroid disease: a hypothesis-generating review ENSG00000003436 ENSG00000122194 PMC10474868__F1 Polyhydroxylated Fullerene C60(OH)40 Nanofilms Promote the Mesenchymal–Epithelial Transition of Human Liver Cancer Cells via the TGFB1/Smad Pathway ENSG00000170558 PMC12098228__F2 Baicalein and baicalin significantly influences apoptosis in colorectal cancer cells ENSG00000087245 ENSG00000134057 ENSG00000132646 ENSG00000116717 ENSG00000100985 PMC11201817__F2 The influence of curcumin on mammalian DHA synthesis pathway and its neuroprotective effect [61] ENSG00000134824 PMC12098228__F3 Baicalin inhibits colorectal cancer metastasis by targeting key migration and invasion pathways ENSG00000134057 ENSG00000170558 ENSG00000026508 PMC5343289__F2 Crosstalk between autophagy and inflammatory signaling pathways: balancing host defence and homeostasis ENSG00000177169 ENSG00000162711 ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000111537 ENSG00000144895 ENSG00000125538 ENSG00000160703 ENSG00000172936 ENSG00000168610 PMC12098228__F1 Baicalein and baicalin suppressing proliferation in colorectal cancer ENSG00000135446 ENSG00000132646 ENSG00000198793 ENSG00000168036 PMC6577427__F1 NAD+ salvage pathway in mammals ENSG00000105835 ENSG00000123572 PMC9408924__F5 Differentially CTCF-Binding Sites in Cattle Rumen Tissue during Weaning ENSG00000095739 ENSG00000187720 ENSG00000113558 ENSG00000156574 ENSG00000205250 PMC10740672__F8 Growth suppression mediated by p53 PMC10973673__F1 Crosstalk between non-coding RNAs and cell-cycle events: A new frontier in cancer therapy ENSG00000149311 ENSG00000175054 ENSG00000134982 ENSG00000135446 ENSG00000123374 ENSG00000133740 ENSG00000205250 ENSG00000105810 ENSG00000096717 ENSG00000105723 PMC7878365__F3 Sestrin modulates cell signaling networks in physiological responses to environmental stresses ENSG00000177169 ENSG00000128272 ENSG00000149212 ENSG00000144895 ENSG00000100219 ENSG00000285069 ENSG00000080546 ENSG00000079999 PMC3205232__F1 A brief survey of mRNA surveillance ENSG00000108557 ENSG00000198585 ENSG00000172795 PMC5782799__F5 Gene interaction network ENSG00000036549 ENSG00000150991 ENSG00000109906 ENSG00000113520 ENSG00000145386 ENSG00000159335 ENSG00000177054 PMC9157790__F2 Wnt Signaling in the Breast: From Development to Disease ENSG00000156076 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC3321453__F6 Vitamin D pathway and sites of interaction with dietary factors ENSG00000152266 ENSG00000019186 PMC6081565__F1 Two classic pathways of necroptosis ENSG00000102871 ENSG00000168404 PMC9157790__F4 Wnt Signaling in the Breast: From Development to Disease ENSG00000101282 ENSG00000156076 ENSG00000281324 ENSG00000162337 ENSG00000133067 ENSG00000120057 ENSG00000050165 ENSG00000104371 ENSG00000168036 ENSG00000104332 ENSG00000155760 PMC9445553__F4 Immune responses to different Uropathogens call individual interventions for bladder infection ENSG00000198830 ENSG00000167207 ENSG00000136869 ENSG00000165799 PMC9405604__F4 Depletion of Mdig Changes Proteomic Profiling in Triple Negative Breast Cancer Cells ENSG00000163435 ENSG00000102034 ENSG00000127191 ENSG00000135506 PMC5800786__F4 Metabolic Regulation of Immune Responses ENSG00000198793 ENSG00000175104 ENSG00000168685 PMC4428658__F3 Eculizumab and Recurrent C3 Glomerulonephritis ENSG00000039537 ENSG00000113600 PMC4731654__F3 Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC8450343__F6 Differential Expression of Immune Response Genes in Asymptomatic Chronic Chagas Disease Patients Versus Healthy Subjects ENSG00000139193 ENSG00000159128 ENSG00000197272 ENSG00000027697 ENSG00000171791 ENSG00000168811 ENSG00000135077 ENSG00000150782 ENSG00000111537 ENSG00000115415 ENSG00000184371 ENSG00000164400 ENSG00000113302 ENSG00000104432 ENSG00000113525 ENSG00000073861 ENSG00000026103 PMC4624297__F4 Comparison of typical innate immune signaling cascades (top panel) with those activated by CJD infection (bottom panel) ENSG00000169245 ENSG00000213928 ENSG00000187608 ENSG00000115415 ENSG00000157601 ENSG00000142166 PMC4650800__F5 Larynx carcinoma regulates tumor-associated macrophages through PLGF signaling ENSG00000105329 ENSG00000149968 ENSG00000100985 PMC7999177__F2 Transcriptomic alteration-based identification of potential diseases and functions modulated upon leptin upregulation ENSG00000262406 ENSG00000148346 ENSG00000288411 ENSG00000115008 ENSG00000149968 ENSG00000140285 ENSG00000100985 ENSG00000073756 ENSG00000143387 PMC3349255__F7 Schematic diagram of a cross-regulation network between FOXA1 and the ErbB2 signaling pathway in ER-negative breast cancer ENSG00000104856 ENSG00000149269 ENSG00000129514 PMC2712597__F6 Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways ENSG00000124217 ENSG00000167118 PMC4498776__F6 Global Transcriptomic Profiling of Cardiac Hypertrophy and Fatty Heart Induced by Long-Term High-Energy Diet in Bama Miniature Pigs ENSG00000172680 ENSG00000147862 ENSG00000197721 ENSG00000138798 ENSG00000130159 ENSG00000127191 ENSG00000128272 ENSG00000170458 ENSG00000125538 ENSG00000175104 ENSG00000146648 ENSG00000100625 ENSG00000026103 PMC2712597__F1 Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways ENSG00000033178 ENSG00000187608 ENSG00000120686 ENSG00000034713 ENSG00000144848 ENSG00000285246 ENSG00000116030 ENSG00000145782 ENSG00000184900 PMC7354691__F4 Interaction network downstream of Atoh7 ENSG00000125755 ENSG00000122218 ENSG00000138495 ENSG00000261236 ENSG00000171940 ENSG00000197429 ENSG00000158195 ENSG00000134748 ENSG00000172113 ENSG00000119969 ENSG00000111011 ENSG00000115421 ENSG00000055950 ENSG00000166166 ENSG00000185049 ENSG00000122873 ENSG00000108821 PMC7503925__F6 Pigment-type switching controlled by dual signaling from MC1R ENSG00000102858 ENSG00000101440 ENSG00000198125 PMC3124513__F6 Integrated Bio-Entity Network: A System for Biological Knowledge Discovery ENSG00000245848 ENSG00000143549 ENSG00000120899 ENSG00000171051 ENSG00000171303 PMC3960869__F2 Interaction of Neisserial surface molecules with the complement system ENSG00000039537 ENSG00000113600 ENSG00000166278 PMC4073605__F7 Proposed model for the formation of reactive oxygen species at mitochondria, activation of Nrf2, and regulation of phase 2 gene expression in the nucleus ENSG00000124102 ENSG00000178573 ENSG00000079999 PMC2768581__F2 Role of Cross Talk between PI3-Kinase and ERK/MAP Kinase Pathways in Artery-Vein Specification ENSG00000196411 ENSG00000164690 PMC2858157__F6 Reconstruction of Gene Regulatory Modules in Cancer Cell Cycle by Multi-Source Data Integration ENSG00000113649 ENSG00000163568 ENSG00000143458 ENSG00000066230 ENSG00000168040 ENSG00000076003 ENSG00000171606 ENSG00000183765 ENSG00000197372 ENSG00000012048 ENSG00000152669 ENSG00000100106 ENSG00000177606 ENSG00000070950 ENSG00000131323 ENSG00000099326 PMC5980236__F1 Compartmentalized Metabolic Engineering for Artemisinin Biosynthesis and Effective Malaria Treatment by Oral Delivery of Plant Cells ENSG00000110921 ENSG00000197429 PMC3747497__F1 FGF signalling: diverse roles during early vertebrate embryogenesis ENSG00000033327 ENSG00000291971 PMC2858157__F7 Reconstruction of Gene Regulatory Modules in Cancer Cell Cycle by Multi-Source Data Integration ENSG00000280831 ENSG00000163564 ENSG00000136492 ENSG00000157764 ENSG00000118526 ENSG00000105656 ENSG00000149308 ENSG00000131023 ENSG00000012048 ENSG00000152684 ENSG00000175376 ENSG00000107949 ENSG00000058600 ENSG00000168806 ENSG00000143476 ENSG00000112984 ENSG00000112378 PMC2858157__F8 Reconstruction of Gene Regulatory Modules in Cancer Cell Cycle by Multi-Source Data Integration ENSG00000094804 ENSG00000171720 ENSG00000092853 ENSG00000087586 ENSG00000146143 ENSG00000145386 ENSG00000164305 ENSG00000282899 ENSG00000134531 PMC2858157__F9 Reconstruction of Gene Regulatory Modules in Cancer Cell Cycle by Multi-Source Data Integration ENSG00000105993 ENSG00000094804 ENSG00000105325 ENSG00000171720 ENSG00000092853 ENSG00000143476 ENSG00000132646 ENSG00000146143 ENSG00000145386 ENSG00000282899 ENSG00000134531 PMC6930397__F5 Functional protein interaction network of PLOD family genes ENSG00000166794 ENSG00000087245 ENSG00000092758 ENSG00000112280 ENSG00000106333 ENSG00000106397 ENSG00000113140 ENSG00000168487 ENSG00000166147 ENSG00000125398 ENSG00000111799 ENSG00000170275 ENSG00000083444 ENSG00000291748 ENSG00000084636 ENSG00000163710 ENSG00000152952 ENSG00000087116 ENSG00000187955 ENSG00000049089 PMC2592809__F9 Scheme summarises different intracellular pathways during osteoblast differentiation which include promoting (blue) and inhibiting (red) factors and are mainly mediated by Smad proteins ENSG00000154342 ENSG00000137834 ENSG00000157933 ENSG00000120149 ENSG00000168036 ENSG00000138071 ENSG00000064195 PMC4654378__F2 NOX system is central to host defense ENSG00000162711 ENSG00000124479 ENSG00000167207 ENSG00000140279 ENSG00000125538 ENSG00000086991 ENSG00000162692 PMC9231311__F4 Indigenous Uses, Phytochemical Analysis, and Anti-Inflammatory Properties of Australian Tropical Medicinal Plants ENSG00000278718 ENSG00000111537 PMC6363620__F3 Complex interplay between CCT and actin and tubulin ENSG00000178690 PMC12243265__F9 RGCs damage in glaucoma were ameliorated via Gut microbiota-IAA-eye signaling pathway ENSG00000125538 ENSG00000198125 ENSG00000106546 PMC5323256__F8 Glycogen Synthase Kinase-3B Induces Neuronal Cell Death via Direct Phosphorylation of Mixed Lineage Kinase 3 PMC4820873__F6 Schematic model of IGF1R-evoked and p110Beta-evoked resistance to p110A inhibition in PIK3CA mutant breast cancer cells ENSG00000169047 ENSG00000198793 ENSG00000121879 ENSG00000140443 PMC3562627__F2 EGFR monoclonal antibodies (MoABs) cetuximab/panitumab, and BRAF inhibitors in BRAF mutated colorectal cancer ENSG00000157764 ENSG00000146648 PMC4381257__F1 Important ECM molecules and ECM receptors involved in cancer cell invasion ENSG00000087245 ENSG00000163914 ENSG00000026508 ENSG00000100985 PMC6724557__F1 TNFR2 can modulate TNFR1 signaling ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC6724557__F3 Model of TNFR2-mediated regulation of NFKB transcriptions factors in Tregs ENSG00000104856 ENSG00000173039 ENSG00000127191 PMC6768886__F7 MiR-532-3p suppresses colorectal cancer progression by disrupting the ETS1/TGM2 axis-mediated Wnt/Beta-catenin signaling ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000155760 PMC2374711__F5 Proposed model of APL pathogenesis induced by PML-RARA ENSG00000138795 ENSG00000113649 ENSG00000001167 ENSG00000101057 ENSG00000122877 ENSG00000069667 ENSG00000138378 ENSG00000159216 ENSG00000183337 ENSG00000173757 ENSG00000175832 ENSG00000150907 ENSG00000177200 ENSG00000066136 ENSG00000269404 ENSG00000150347 ENSG00000136518 ENSG00000123268 ENSG00000140464 ENSG00000108312 PMC9250635__F1 CGAS activation and cGAS-STING signaling ENSG00000183735 ENSG00000164430 PMC9250635__F2 CGAS activity in cells ENSG00000164430 ENSG00000137757 ENSG00000196954 ENSG00000247315 ENSG00000164305 PMC3649977__F2 STL-based Analysis of TRAIL-induced Apoptosis Challenges the Notion of Type I/Type II Cell Line Classification ENSG00000039537 ENSG00000171791 PMC6542701__F2 ER’s coregulatory proteins and genomic binding sites differ between endometrial cancer and breast cancer cells ENSG00000175832 ENSG00000129514 ENSG00000107485 ENSG00000196208 PMC5549027__F15 Anacardic acid induces cell apoptosis of prostatic cancer through autophagy by ER stress/DAPK3/Akt signaling pathway ENSG00000198793 PMC11502381__F2 Bidirectional regulation of the cGAS-STING pathway and immune cells in the tumor immunosuppression microenvironment (A) The cGAS-STING pathway inhibits M2 macrophage polarization and promotes anti-tumor immunity ENSG00000108691 ENSG00000164430 ENSG00000108688 ENSG00000112561 ENSG00000049768 ENSG00000121807 ENSG00000168610 ENSG00000007171 PMC8657039__F2 Early TP53 Alterations Shape Gastric and Esophageal Cancer Development ENSG00000149311 ENSG00000175054 PMC5442340__F4 KEGG pathway for Hippo signaling pathway ENSG00000126016 ENSG00000109321 ENSG00000136997 ENSG00000168036 ENSG00000150457 ENSG00000081051 ENSG00000100485 ENSG00000131023 ENSG00000169435 PMC7263595__F1 Intragenic suppressor mutations of the COQ8 protein kinase homolog restore coenzyme Q biosynthesis and function in Saccharomyces cerevisiae ENSG00000132423 ENSG00000167113 ENSG00000119723 ENSG00000110871 ENSG00000088682 ENSG00000173085 ENSG00000167186 PMC5442340__F5 KEGG pathway for PI3K-Akt signaling pathway ENSG00000124102 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000136997 ENSG00000104894 PMC5082287__F3 Pathway depicting Beta-hydroxy-Beta-methylbutyrate (HMB)-modulated genes identified in the present analysis, which could directly or indirectly affect skeletal muscle cell functions ENSG00000144834 ENSG00000186660 ENSG00000288411 ENSG00000111049 ENSG00000147166 ENSG00000165996 ENSG00000130702 ENSG00000181104 ENSG00000149485 ENSG00000081189 ENSG00000198947 PMC6981772__F2 Plant sterol and cholesterol metabolism ENSG00000005471 ENSG00000184831 ENSG00000120437 PMC4631354__F3 Characterization of SCDs as Membrane Maintenance Regulators ENSG00000083857 ENSG00000165323 PMC5082287__F5 Relevance network over-viewing discussed relationships between Beta-hydroxy-Beta-methylbutyrate (HMB)-modulated genes and cell processes (Pathway Studio Web Mammalian) ENSG00000011198 ENSG00000007171 ENSG00000198947 PMC9369281__F2 MicroRNAs in Inflammatory Bowel Disease and Its Complications ENSG00000120913 ENSG00000168610 PMC5539204__F6 Complexity of the miRNA-mRNA interactome network in rat soleus muscles with cardiac cachexia ENSG00000169436 ENSG00000156103 ENSG00000171914 ENSG00000112562 ENSG00000150093 PMC4107940__F1 General interplay between the canonical TLR signaling pathway, the cytokine-mediated DNA repair feedback loop, and the growth factors-mediated signaling pathway ENSG00000012061 ENSG00000012048 ENSG00000138378 ENSG00000079246 ENSG00000115415 ENSG00000172005 ENSG00000189403 ENSG00000051180 ENSG00000172936 ENSG00000150455 ENSG00000168610 ENSG00000136936 PMC7470101__F1 Role of cytokines in mediating communication between immune cells ENSG00000171855 ENSG00000150782 ENSG00000111537 ENSG00000197272 ENSG00000164136 ENSG00000164399 ENSG00000113520 ENSG00000166090 ENSG00000104432 ENSG00000162892 ENSG00000113525 PMC8247566__F2 MiR-126 pro- and anti-angiogenic function in different cell-types ENSG00000197713 ENSG00000105647 ENSG00000162692 ENSG00000267534 PMC3448682__F7 Genome-Wide Expression Profiling Identifies Type 1 Interferon Response Pathways in Active Tuberculosis ENSG00000171855 ENSG00000185215 ENSG00000089127 ENSG00000135148 ENSG00000156587 ENSG00000137193 ENSG00000162654 PMC10985261__F12 The VDR-mTOR Signaling Pathway in DKD Development ENSG00000168209 ENSG00000198793 PMC4676991__F2 Autophagic signaling pathways associated with oxidative stress ENSG00000149311 ENSG00000177169 ENSG00000198382 PMC7098960__F2 The immune response induced by polygenic diseases related to the composition of the intestinal microbiota in patients with IBS and healthy subjects ENSG00000162594 ENSG00000096996 ENSG00000167207 ENSG00000105397 ENSG00000152127 ENSG00000110324 ENSG00000150455 ENSG00000175104 ENSG00000168610 PMC8058464__F1 Transcriptional signature of Leishmania infected macrophage ENSG00000198793 ENSG00000113520 ENSG00000096717 ENSG00000026103 PMC6057036__F7 RASAL2-mediated hippo signaling pathway ENSG00000150457 ENSG00000131023 PMC6836336__F3 GREM1 expression is associated with genes involved in collagen formation and extracellular matrix (ECM) organization ENSG00000164932 ENSG00000162493 ENSG00000120820 ENSG00000102359 ENSG00000166147 ENSG00000136859 ENSG00000186340 ENSG00000157227 ENSG00000038427 ENSG00000078098 ENSG00000087116 ENSG00000123610 ENSG00000087245 ENSG00000137273 ENSG00000149380 ENSG00000086991 ENSG00000113140 ENSG00000168487 ENSG00000148848 ENSG00000151388 ENSG00000143387 ENSG00000133110 ENSG00000134013 ENSG00000107249 ENSG00000116132 ENSG00000174099 ENSG00000106624 PMC9598787__F7 Prevention of Testicular Damage by Indole Derivative MMINA via Upregulated StAR and CatSper Channels with Coincident Suppression of Oxidative Stress and Inflammation: In Silico and In Vivo Validation ENSG00000102871 PMC4254277__F2 Protein and Amino Acid Restriction, Aging and Disease: from yeast to humans ENSG00000128272 ENSG00000198793 PMC11011407__F2 Clinical Relevance of the EPH/Ephrin Signaling Pathway in Pediatric Solid and Hematologic Malignancies ENSG00000142627 ENSG00000070831 ENSG00000116106 ENSG00000198793 ENSG00000077782 ENSG00000126458 ENSG00000133216 PMC11011407__F3 Clinical Relevance of the EPH/Ephrin Signaling Pathway in Pediatric Solid and Hematologic Malignancies ENSG00000196411 ENSG00000135446 ENSG00000154928 ENSG00000133216 PMC11011407__F4 Clinical Relevance of the EPH/Ephrin Signaling Pathway in Pediatric Solid and Hematologic Malignancies ENSG00000142627 ENSG00000135333 PMC6403468__F13 Model of ApoER2 and VLDLR mediated signaling during cortical development ENSG00000173406 PMC3897553__F8 Neural Epidermal Growth Factor-Like Like Protein 2 (NELL2) Promotes Aggregation of Embryonic Carcinoma P19 Cells by Inducing N-Cadherin Expression ENSG00000170558 ENSG00000185591 PMC10526485__F2 Mitochondrial Calcium Uniporter (MCU): Molecular Identity and Role in Human Diseases ENSG00000005059 ENSG00000107745 ENSG00000156026 ENSG00000155970 PMC7294139__F3 Gene ontology and pathway enrichment and network analysis of blue module genes ENSG00000100234 ENSG00000169436 ENSG00000107562 ENSG00000106333 ENSG00000186340 ENSG00000133110 ENSG00000038427 ENSG00000157227 ENSG00000291748 PMC11016919__F1 Trimetazidine May Potentially Confer Neuroprotective Effects against COVID-19-Induced Neurological Sequelae via Inhibition of Death-Associated Protein Kinase 1 (DAPK1) Signaling Pathways: An Evidenced-Based Hypothesis PMC6694821__F6 Protein interactome of genes downregulated upon productive HPV16 infection of epithelial tissue types ENSG00000143799 ENSG00000213928 ENSG00000105835 ENSG00000187608 ENSG00000058085 ENSG00000089127 ENSG00000183486 ENSG00000134215 ENSG00000159388 ENSG00000157601 ENSG00000070669 ENSG00000069667 ENSG00000288411 ENSG00000134321 ENSG00000292234 ENSG00000197943 ENSG00000182667 ENSG00000135919 ENSG00000282830 ENSG00000138449 ENSG00000185022 ENSG00000008513 ENSG00000185745 ENSG00000163736 ENSG00000116741 ENSG00000166670 ENSG00000276561 ENSG00000143375 ENSG00000109814 ENSG00000273992 ENSG00000108839 ENSG00000224320 ENSG00000069482 ENSG00000134827 ENSG00000163235 ENSG00000185201 ENSG00000146070 ENSG00000111331 ENSG00000115009 ENSG00000073737 ENSG00000152409 ENSG00000125740 ENSG00000033327 ENSG00000242110 ENSG00000088826 ENSG00000007237 ENSG00000163739 ENSG00000159461 ENSG00000196154 ENSG00000124107 ENSG00000198265 ENSG00000172155 ENSG00000137393 ENSG00000148344 ENSG00000136695 ENSG00000183018 ENSG00000111907 ENSG00000196586 ENSG00000136688 ENSG00000137959 ENSG00000135899 ENSG00000150556 ENSG00000132530 ENSG00000186226 ENSG00000180667 ENSG00000178607 ENSG00000077150 ENSG00000150991 ENSG00000105289 ENSG00000215853 ENSG00000146072 ENSG00000148798 ENSG00000153802 ENSG00000125538 ENSG00000276051 ENSG00000143622 ENSG00000136235 ENSG00000101213 ENSG00000027075 ENSG00000148346 ENSG00000010704 ENSG00000065361 ENSG00000113070 ENSG00000115267 ENSG00000273686 ENSG00000176153 ENSG00000143631 ENSG00000165795 ENSG00000284816 ENSG00000067066 ENSG00000149809 ENSG00000010810 ENSG00000135114 ENSG00000116761 PMC7423683__F4 Notch and the Regulation of Osteoclast Differentiation and Function ENSG00000148400 ENSG00000074181 ENSG00000125538 ENSG00000114315 PMC12045470__F5 Sepsis-induced liver injury ENSG00000167468 ENSG00000136869 PMC12045470__F6 Sepsis-induced myocardial injury ENSG00000162711 ENSG00000167468 ENSG00000086991 ENSG00000189403 ENSG00000136869 PMC12045470__F3 Sepsis-induced lung injury ENSG00000162711 ENSG00000176256 ENSG00000167996 ENSG00000136869 PMC12045470__F4 Sepsis-induced kidney injury ENSG00000162711 ENSG00000151012 ENSG00000167468 ENSG00000086991 ENSG00000136869 PMC9324529__F1 Immunosuppressive Mechanisms in Brucellosis in Light of Chronic Bacterial Diseases ENSG00000136869 ENSG00000146648 PMC8899123__F3 Molecular Docking as a Therapeutic Approach for Targeting Cancer Stem Cell Metabolic Processes ENSG00000145604 ENSG00000198793 ENSG00000113558 ENSG00000164690 ENSG00000083720 ENSG00000128602 PMC4099420__F6 Gene Expression Profiling of the Response to Interferon Beta in Epstein-Barr-Transformed and Primary B Cells of Patients with Multiple Sclerosis ENSG00000132109 ENSG00000089127 ENSG00000140968 ENSG00000163568 ENSG00000157601 ENSG00000115267 ENSG00000185745 ENSG00000027697 ENSG00000160710 ENSG00000276561 ENSG00000128394 ENSG00000172183 ENSG00000239732 ENSG00000135114 ENSG00000239713 ENSG00000132256 ENSG00000172936 ENSG00000288185 ENSG00000111331 PMC8017232__F7 Proposed model depicting the involvement of TIPE2 in the RIG-I signaling pathway ENSG00000183735 ENSG00000088888 PMC12045470__F2 Protective mechanism of dexmedetomidine against multiorgan dysfunction ENSG00000278718 ENSG00000162711 ENSG00000198793 ENSG00000086991 ENSG00000189403 ENSG00000136869 PMC10374575__F6 GHS-R1a/D2R heterodimers activation in dopaminergic neurons ENSG00000069482 PMC4179756__F13 Ferulago angulata activates intrinsic pathway of apoptosis in MCF-7 cells associated with G1 cell cycle arrest via involvement of p21/p27 ENSG00000115317 PMC4071201__F1 Depiction of the systematic procedure to study drug resistance in MM ENSG00000163235 ENSG00000198793 ENSG00000169047 ENSG00000095015 ENSG00000136869 ENSG00000175104 ENSG00000135341 ENSG00000127191 ENSG00000146648 PMC4071201__F2 p38 MAPK isoforms for drug resistance ENSG00000169291 ENSG00000108557 ENSG00000169047 ENSG00000198793 ENSG00000173599 PMC8498061__F2 Myricetin: A comprehensive review on its biological potentials ENSG00000100084 ENSG00000138798 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC9201453__F2 Targeting Thyroid Hormone/Thyroid Hormone Receptor Axis: An Attractive Therapy Strategy in Liver Diseases ENSG00000149968 ENSG00000137193 ENSG00000123374 ENSG00000185591 PMC9201453__F3 Targeting Thyroid Hormone/Thyroid Hormone Receptor Axis: An Attractive Therapy Strategy in Liver Diseases ENSG00000151365 ENSG00000071539 ENSG00000165795 ENSG00000197461 PMC7056742__F2 Activation of NLRP3 inflammasome has involved in the pathogenesis of several renal diseases including acute kidney injury (AKI), chronic kidney disease (CKD), diabetic nephropathy (DN), IgA nephropathy (IgAN), etc ENSG00000162711 ENSG00000125538 ENSG00000168040 PMC4620942__F5 Modeling the calcium-mediated pro-apoptotic action of less toxic natural products ENSG00000171105 ENSG00000128272 ENSG00000144895 PMC10520667__F7 LncRNA DLX6-AS1/miR-16-5p axis regulates autophagy and apoptosis in non-small cell lung cancer: A Boolean model of cell death ENSG00000177169 ENSG00000168283 ENSG00000198793 PMC4184083__F1 Addition of RASAL1 to the canonical scheme of the RAS-coupled MAPK and PI3K pathways ENSG00000157764 ENSG00000198793 ENSG00000111344 PMC4601496__F1 Manipulation of neutrophil function by P ENSG00000172005 ENSG00000172936 PMC3627065__F8 Factors situated at the interface between the ubiquitin-proteasome and the autophagy-lysosome degradative systems ENSG00000198793 ENSG00000151929 PMC3627065__F6 Integrated view of mammalian autophagy ENSG00000152348 ENSG00000110497 ENSG00000198382 ENSG00000126775 ENSG00000144848 ENSG00000171791 ENSG00000145782 ENSG00000057663 PMC3829803__F7 Retinoid action during paramyxovirus infection ENSG00000213928 ENSG00000088888 ENSG00000125347 ENSG00000276561 ENSG00000142166 PMC3954580__F5 MEK5/ERK5 Pathway: The first fifteen years ENSG00000002330 ENSG00000291971 ENSG00000138798 ENSG00000170558 ENSG00000019549 ENSG00000168036 ENSG00000128342 ENSG00000168610 ENSG00000081189 PMC9266688__F8 Tumor-Suppressor Role of the A1-Na/K-ATPase Signalosome in NASH Related Hepatocellular Carcinoma ENSG00000291971 ENSG00000150907 ENSG00000198793 ENSG00000146648 PMC6377309__F1 SAMHD1 down-regulates the IFN-I pathway ENSG00000183735 ENSG00000164430 ENSG00000107201 PMC6377309__F2 SAMHD1 prevents the activation of NFKB signaling ENSG00000104856 ENSG00000125347 PMC1764624__F1 Synthesis and breakdown of proteins by amino acids ENSG00000169047 ENSG00000198793 PMC6377309__F5 Role of SAMHD1 in the crosstalk between innate and adaptive immune responses ENSG00000134982 PMC10222038__F1 Vitamin D metabolic pathway ENSG00000111012 ENSG00000080823 ENSG00000186104 PMC4543607__F1 Major EDCF-mediated signalling pathways in hypertension and diabetes ENSG00000163914 PMC8479196__F3 Intra- and Extracellular Lipid Signals in Cancer Stemness and Potential Therapeutic Strategy ENSG00000135218 ENSG00000169710 ENSG00000167419 PMC8479196__F1 Intra- and Extracellular Lipid Signals in Cancer Stemness and Potential Therapeutic Strategy ENSG00000178860 ENSG00000135218 ENSG00000169710 PMC3091682__F2 Correlation of Predicted miRNA Targets with Hosts ENSG00000132906 ENSG00000002330 ENSG00000277893 ENSG00000150907 ENSG00000198793 ENSG00000123374 ENSG00000169032 ENSG00000139687 ENSG00000197461 PMC9513149__F1 DNA damage response and GATA4 signaling in cellular senescence and aging-related pathology ENSG00000149311 ENSG00000175054 ENSG00000285109 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC9201453__F4 Targeting Thyroid Hormone/Thyroid Hormone Receptor Axis: An Attractive Therapy Strategy in Liver Diseases ENSG00000184979 ENSG00000153827 PMC4177605__F3 PPAR signaling pathway from KEGG ENSG00000150991 ENSG00000100979 PMC3954580__F2 MEK5 regulation and downstream targets ENSG00000169554 ENSG00000002330 ENSG00000291971 ENSG00000138798 ENSG00000019549 ENSG00000128342 PMC5352205__F8 Epigenetically upregulated WIPF1 plays a major role in BRAF V600E-promoted papillary thyroid cancer aggressiveness ENSG00000157764 ENSG00000100985 PMC5863775__F1 MST2-RASSF protein–protein interactions through SARAH domains ENSG00000150457 ENSG00000131023 ENSG00000026103 PMC8694249__F1 Phosphatases of regenerating liver are key regulators of metabolism in cancer cells – role of Serine/Glycine metabolism ENSG00000092621 ENSG00000135069 ENSG00000146733 ENSG00000178445 PMC4162761__F1 Biosynthesis and Roles of Phospholipids in Mitochondrial Fusion, Division and Mitophagy ENSG00000163624 ENSG00000173599 ENSG00000184207 ENSG00000186281 ENSG00000166123 PMC5325784__F2 HPV E6 and E7 interacts with core components of the interferon pathway ENSG00000213928 ENSG00000164430 ENSG00000115415 ENSG00000131323 ENSG00000125347 ENSG00000276561 ENSG00000142166 PMC6423448__F1 Key components of the Hippo pathway in Drosophila and mammals ENSG00000186575 ENSG00000150457 PMC6006200__F2 Fe/S cluster biogenesis ENSG00000274619 PMC2886068__F2 Bile salt synthetic pathways ENSG00000167910 ENSG00000099377 ENSG00000135929 PMC7568356__F3 CircRNA-miRNA-mRNA networks in hematological malignancies ENSG00000104290 ENSG00000168036 PMC3387579__F1 De novo DAG/TAG synthesis (Kennedy pathway) ENSG00000198670 ENSG00000173402 ENSG00000026103 PMC6691039__F1 Platelet Theory ENSG00000213658 PMC4018451__F1 The IRS-1→PI3K→Akt insulin signaling pathway ENSG00000002330 ENSG00000005882 ENSG00000169047 PMC4018451__F2 Schematic summary of hippocampal formation alterations in the IR→IRS-1→PI3K→Akt→mTOR signaling pathway of AD dementia cases versus age- and gender-matched controls ENSG00000005882 ENSG00000169047 ENSG00000198793 ENSG00000105723 PMC6691039__F2 Endothelial theory ENSG00000110799 PMC8460702__F5 Growth hormone promotes hepatic gluconeogenesis by enhancing BTG2–YY1 signaling pathway ENSG00000100811 ENSG00000159388 ENSG00000124253 PMC5346332__F3 Role of Aim2 protein in non lupus-prone and lupus-prone strains of mice in the regulation of type I IFNs production ENSG00000183735 ENSG00000213928 ENSG00000163568 ENSG00000276561 ENSG00000142166 PMC8034456__F8 The beneficial effects of FGF19 on muscle atrophy, metabolic homeostasis and irisin secretion in skeletal muscle ENSG00000122180 ENSG00000169047 ENSG00000106459 PMC8155122__F3 Biased signaling of oxycodone and morphine ENSG00000146648 ENSG00000196689 PMC7198830__F1 Direct cardiotoxic effects of anti-cancer therapies in cardiomyocytes ENSG00000002330 ENSG00000291971 ENSG00000198793 ENSG00000178568 PMC9060002__F7 Data suggest multiple potentially active epithelial–mesenchymal transition-associated pathways in CF, with YAP1 mediating their crosstalk ENSG00000138795 ENSG00000143546 ENSG00000136997 ENSG00000001626 PMC9706580__F8 Mutant Kras and mTOR crosstalk drives hepatocellular carcinoma development via PEG3/STAT3/BEX2 signaling ENSG00000198793 ENSG00000133134 ENSG00000168610 ENSG00000198300 PMC5346332__F1 Constitutive low levels of IFNB that are produced by most cell types “prime” type I IFNs producing cells for a robust type I IFNs production upon sensing “danger” signals such as cytosolic DNA and TLR ligands ENSG00000183735 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000276561 ENSG00000142166 PMC10594068__F3 Bone is a tissue that consists of diverse cell types (osteoblasts, osteoclasts) that interact in a complex manner ENSG00000178860 ENSG00000152266 PMC6094638__F3 Anti-inflammatory function of tumor necrosis factor receptor-associated factor (TRAF)2 and TRAF3 in toll-like receptor (TLR) signaling pathway ENSG00000173039 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC4148386__F3 MAPK signaling pathway ENSG00000087095 ENSG00000105329 ENSG00000170458 ENSG00000152689 ENSG00000026103 PMC8327900__F1A What Are the Clinical and Systemic Results of Periodontitis Treatment in Obese Individuals? ENSG00000157500 ENSG00000171105 ENSG00000159346 ENSG00000285070 PMC6407861__F1 Assembling a protective shield ENSG00000012048 ENSG00000080345 ENSG00000253251 ENSG00000171984 ENSG00000122376 ENSG00000082212 PMC8928443__F4 Association of the Microbiota and Pancreatic Cancer: Opportunities and Limitations ENSG00000173599 ENSG00000065559 ENSG00000172936 ENSG00000168610 PMC6094638__F1 Function and regulation of tumor necrosis factor receptor-associated factor (TRAF)6 in MyD88 signaling pathway ENSG00000264522 ENSG00000136878 ENSG00000172936 ENSG00000157625 ENSG00000083799 ENSG00000162601 ENSG00000175104 PMC7125957__F1 B9 metabolism comprising the thymidylate cycle (red diagram), the methionine cycle (green diagram) and the purine biosynthesis pathway (blue diagram) ENSG00000228716 ENSG00000205221 PMC7125957__F2 Vitamin B6 metabolism in humans ENSG00000291814 PMC10966134__F8 Schematic illustrating the proposed mechanism by which the PERK pathway modulates autophagy during RACK1‐mediated neuroprotection after TBI ENSG00000128272 ENSG00000144895 ENSG00000057663 PMC6657611__F2 Notch-targeting therapeutic approaches in TNBCs ENSG00000148400 ENSG00000074181 ENSG00000182667 PMC5138043__F2 FAT4 participates in tumor transformation through the Hippo–Wnt signaling pathway by inducing YAP–TAZ activation.Notes: Src-mediated tumorigenesis also results from Src activation to repress FAT4 gene expression via MEK/ERK or cofilin1 ENSG00000291971 ENSG00000134982 ENSG00000168036 ENSG00000164916 PMC8216017__F1 CXCL12 in Kidney Diseases: A Friend or Foe? ENSG00000107562 ENSG00000164690 ENSG00000121966 PMC8216017__F2 CXCL12 in Kidney Diseases: A Friend or Foe? ENSG00000107562 ENSG00000002330 ENSG00000197635 ENSG00000135605 ENSG00000121966 PMC9004567__F5 Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine ENSG00000019991 ENSG00000107562 ENSG00000136457 ENSG00000118785 ENSG00000198793 ENSG00000136997 ENSG00000213341 ENSG00000113263 ENSG00000006459 PMC7201649__F10 Copper Induces Oxidative Stress and Apoptosis in the Mouse Liver ENSG00000102871 ENSG00000168040 ENSG00000106546 ENSG00000026103 PMC9001970__F1 Evolving Roles of Notch Signaling in Cortical Development ENSG00000148400 ENSG00000074181 ENSG00000184916 PMC3544113__F1 Main deregulated signaling pathways in PMBCL ENSG00000006062 PMC6584414__F1 Schematic illustration of albumin nanoparticles preparation and their targeted delivery to breast cancer cells and metastatic lymph node ENSG00000113140 ENSG00000214285 ENSG00000128602 PMC6367250__F1 The roles of circRNAs in cancer phenotypes and biological characteristics ENSG00000100234 ENSG00000168036 PMC4894443__F4 Flatworms have lost the right open reading frame kinase 3 gene during evolution ENSG00000141101 ENSG00000101782 ENSG00000058729 ENSG00000135521 PMC5240838__F8 Proteostasis network via the HSF1-SQSTM1 axis ENSG00000183735 ENSG00000284774 ENSG00000284099 PMC6944215__F5 Representation of the adverse outcome pathway (AOP) network involving BPF ENSG00000135446 ENSG00000105810 PMC10384765__F6 Exploring the Molecular Basis of Vesicular Stomatitis Virus Pathogenesis in Swine: Insights from Expression Profiling of Primary Macrophages Infected with M51R Mutant Virus ENSG00000236637 ENSG00000132109 ENSG00000188379 ENSG00000213928 ENSG00000111537 ENSG00000112343 ENSG00000147896 ENSG00000168310 ENSG00000234829 ENSG00000121060 ENSG00000106546 PMC10474147__F2 Necrosis and apoptosis: morphological features and signaling pathways ENSG00000132906 ENSG00000102871 ENSG00000168040 ENSG00000064012 ENSG00000164305 PMC3941921__F3 Highest-scoring downregulated network: Energy Production, Metabolism and Cell Structure ENSG00000163399 ENSG00000145349 ENSG00000108518 PMC3941921__F5 Downregulated network of CANB1 in traumatic brain injury (TBI) ENSG00000188386 PMC6678366__F4 Molecular mechanism of soft-jet plasma-induced cancer cell apoptosis via the mitochondrial intrinsic pathway and extracellular signal-regulated kinase/mitogen-activated protein kinase (ERK/MAPK) activation ENSG00000188486 PMC7667085__F1 Pseudomonas aeruginosa injection (PAI) make the naïve T cell mature through both CD80/86 and MHC-II signal pathway in dendritic cells (DC) PMC2788936__F3 Signaling and regulation of PRR-induced autophagy ENSG00000150782 ENSG00000172936 ENSG00000136869 PMC3941921__F2 Highest scoring upregulated network: Cellular Assembly ENSG00000160789 ENSG00000136541 ENSG00000277586 ENSG00000100285 ENSG00000148798 ENSG00000178209 ENSG00000100345 ENSG00000008056 PMC11484394__F2 Diagram illustrating the regulation of the p53 pathway by miRNAs in prostate cancer (WP3982) ENSG00000132906 ENSG00000105327 ENSG00000149212 ENSG00000205795 ENSG00000198793 ENSG00000196470 ENSG00000164305 ENSG00000183765 ENSG00000149311 ENSG00000172667 ENSG00000112378 ENSG00000120868 ENSG00000120471 ENSG00000064012 PMC3784162__F2 Toll-like receptor 3 (TLR3) participates in both defence and offence in host immunity to viruses ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000164342 PMC4891224__F1 Is There a Future for AKT Inhibitors in the Treatment of Cancer? ENSG00000169047 PMC2784308__F1 An illustration of the MC1R pigmentation pathway and the loci implicated in melanoma risk ENSG00000101440 ENSG00000107165 PMC5399014__F6 Metabolic pathway of lipid accumulation in oleaginous microorganisms and related key enzymes ENSG00000062485 ENSG00000026103 PMC4915479__F4 Major TGFB signaling pathways in vascular cells ENSG00000138795 ENSG00000136535 ENSG00000163914 ENSG00000123374 ENSG00000175104 PMC7277712__F6 Bisphenol A-induced synthesis of steroids: The bisphenol A (BPA) spreads out through the membrane and binds the cytosolic multi-protein aryl hydrocarbon receptor (AhR), allowing its release in the cytoplasm by the heat shock protein (hsp)-90 ENSG00000106546 PMC3304564__F1 PI3K/AKT signaling module and cross-talk with other pathway PMC5846438__F2 Signaling pathways of different amino acids in intestinal inflammation ENSG00000130234 ENSG00000198793 ENSG00000036828 PMC2905406__F10 Illustration of GDNF signaling disruption by coated silver nanoparticles ENSG00000124102 ENSG00000010810 PMC5846438__F1 Possible signaling mechanisms of amino acids in intestinal inflammation in the ECs are illustrated ENSG00000130234 ENSG00000198793 ENSG00000036828 PMC3658307__F2 Liver Ischemia and Reperfusion Injury: New Insights Into Mechanisms of Innate – Adaptive Immune-Mediated Tissue Inflammation ENSG00000169245 ENSG00000186810 ENSG00000158473 ENSG00000108691 ENSG00000138378 ENSG00000239732 ENSG00000125538 ENSG00000189403 ENSG00000169429 ENSG00000136869 PMC7396796__F1 Model representing the molecular signaling pathway of WAVE3 contributing to cancer progression and metastasis ENSG00000138798 PMC10886137__F4 JNK and p38 MAPK signaling pathway of filefish upon Cd exposure ENSG00000102871 ENSG00000130522 ENSG00000172936 ENSG00000127191 PMC8953253__F4 Stimulation of Osteoclast Formation by Oncostatin M and the Role of WNT16 as a Negative Feedback Regulator ENSG00000145623 ENSG00000099985 ENSG00000167941 ENSG00000002745 ENSG00000168610 PMC10886137__F5 Glycolysis pathway of filefish upon Cd exposure ENSG00000074800 ENSG00000159399 PMC10886137__F6 Fatty acid degradation-related pathways of filefish upon Cd exposure ENSG00000157184 ENSG00000102977 PMC10886137__F7 Citrate cycle (TCA cycle) pathway of filefish upon Cd exposure ENSG00000073578 ENSG00000117118 ENSG00000146701 PMC8914342__F3 Emerging Roles and Mechanisms of lncRNA FOXD3-AS1 in Human Diseases ENSG00000143799 ENSG00000066044 ENSG00000160182 ENSG00000154059 ENSG00000102974 PMC1386115__F3 Integration of lipid metabolic and inflammatory signaling in macrophages by LXRs ENSG00000167207 ENSG00000125538 ENSG00000136869 ENSG00000160179 ENSG00000100985 ENSG00000164342 PMC9103147__F3 Proteostasis Perturbations and Their Roles in Causing Sterile Inflammation and Autoinflammatory Diseases ENSG00000164430 PMC6024333__F2 Mechanisms of innate and acquired resistance to immune-checkpoint inhibitors (ICPIs) ENSG00000168036 PMC7528619__F2 Race between Host Antiviral Innate Immunity and the Immune Evasion Strategies of Herpes Simplex Virus 1 ENSG00000164430 ENSG00000163565 ENSG00000168036 PMC7528619__F3 Race between Host Antiviral Innate Immunity and the Immune Evasion Strategies of Herpes Simplex Virus 1 ENSG00000213928 ENSG00000213658 ENSG00000138135 ENSG00000105397 ENSG00000142166 PMC6627600__F1 Interactions between RHOB and EGFR, Ras, PI3K/Akt/mTOR, MYC, and HDAC ENSG00000094631 ENSG00000143878 ENSG00000163235 ENSG00000138798 ENSG00000198793 ENSG00000136997 ENSG00000146648 PMC7249724__F3 Micro-environment favorable for re-pigmentation ENSG00000173599 ENSG00000135903 PMC10743093__F3 Schematic illustration highlighting targets of senotherapeutics including senolytics and senomorphics ENSG00000198793 ENSG00000136235 ENSG00000184481 PMC5749411__F4 Regulation of Granulosa and Theca Cell Transcriptomes During Ovarian Antral Follicle Development ENSG00000149311 ENSG00000110711 ENSG00000002330 ENSG00000102871 ENSG00000172936 ENSG00000166278 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC7531836__F1 Modeling the activation of the alternative complement pathway and its effects on hemolysis in health and disease ENSG00000039537 ENSG00000113600 ENSG00000203710 PMC5749411__F5 Regulation of Granulosa and Theca Cell Transcriptomes During Ovarian Antral Follicle Development ENSG00000137834 ENSG00000111537 ENSG00000090402 ENSG00000100387 ENSG00000198742 ENSG00000156574 ENSG00000134363 ENSG00000164093 PMC2396493__F1 P53 on the IGF-1 signaling pathway ENSG00000198793 ENSG00000164327 PMC8348034__F6 Cigarette Smoke Condensate Exposure Induces Receptor for Advanced Glycation End-Products (RAGE)-Dependent Sterile Inflammation in Amniotic Epithelial Cells ENSG00000125538 ENSG00000189403 PMC8450413__F5 Epigenetic Regulation of the Wnt/Beta-Catenin Signaling Pathway in Cancer ENSG00000134982 ENSG00000102312 ENSG00000168036 PMC2821977__F1 All steroids derive from cholesterol, which can be synthesized within the brain for de novo neurosteroidogenesis () PMC9685566__F9 Transcription level differences in Taxus wallichiana var. mairei elicited by Ce3+, Ce4+ and methyl jasmonate ENSG00000172680 ENSG00000070831 PMC5442293__F1 Role of WIP1 phosphatase in termination of DNA damage response ENSG00000149311 ENSG00000175054 ENSG00000101224 ENSG00000124762 PMC7007436__F7 Pten-mediated Gsk3B modulates the naïve pluripotency maintenance in embryonic stem cells ENSG00000198793 PMC6698381__F3 Pathways involved in sphingolipid metabolism ENSG00000167769 ENSG00000063176 ENSG00000198964 ENSG00000143753 ENSG00000164023 ENSG00000188611 ENSG00000070610 ENSG00000078124 ENSG00000148154 ENSG00000285281 ENSG00000135587 PMC6471604__F1 Mucins: the Old, the New and the Promising Factors in Hepatobiliary Carcinogenesis ENSG00000019991 ENSG00000169550 ENSG00000168036 ENSG00000198125 ENSG00000168646 ENSG00000168610 ENSG00000146648 ENSG00000173702 PMC8686517__F1 TNFA in MS and Its Animal Models: Implications for Chronic Pain in the Disease ENSG00000137275 ENSG00000102871 ENSG00000056558 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC6425566__F3 Mitonuclear communication ENSG00000143799 ENSG00000132463 ENSG00000096717 PMC8450413__F1 Epigenetic Regulation of the Wnt/Beta-Catenin Signaling Pathway in Cancer ENSG00000281324 ENSG00000134982 ENSG00000058091 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC8450413__F2 Epigenetic Regulation of the Wnt/Beta-Catenin Signaling Pathway in Cancer ENSG00000070831 ENSG00000100592 ENSG00000177606 PMC6441546__F4 One-carbon metabolism ENSG00000214435 ENSG00000291507 ENSG00000173638 ENSG00000116984 PMC8450413__F3 Epigenetic Regulation of the Wnt/Beta-Catenin Signaling Pathway in Cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000155011 ENSG00000104332 ENSG00000128602 PMC11042222__F4 Loss of Ffar4 is associated with decreased AMPK signaling and increased cellular senescence in the infarcted myocardium ENSG00000149311 ENSG00000175054 ENSG00000085117 ENSG00000285109 ENSG00000135446 ENSG00000156026 ENSG00000276051 ENSG00000123374 ENSG00000164087 ENSG00000026103 PMC8450413__F4 Epigenetic Regulation of the Wnt/Beta-Catenin Signaling Pathway in Cancer ENSG00000136997 ENSG00000137845 PMC9637639__F6 Identification of the effect and mechanism of Yiyi Fuzi Baijiang powder against colorectal cancer using network pharmacology and experimental validation ENSG00000132906 ENSG00000002330 ENSG00000134982 ENSG00000136997 ENSG00000122008 PMC3734838__F6 Schematic illustration delineating the role of the AKT/Foxo3a/Bim pathway in selenite-induced apoptosis of CRC cells ENSG00000291971 PMC7792222__F2 miRNA-mediated regulation of BCSCs via targeting the Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC10878789__F10 Schematic diagram illustrating the occurrence of asthma ENSG00000177169 ENSG00000162711 ENSG00000198925 PMC7453253__F1 Imbalance of T cells in asthma pathogenesis ENSG00000138378 ENSG00000137033 ENSG00000107485 ENSG00000145777 ENSG00000166090 ENSG00000049768 ENSG00000026103 PMC7528619__F1 Race between Host Antiviral Innate Immunity and the Immune Evasion Strategies of Herpes Simplex Virus 1 ENSG00000183735 ENSG00000239732 ENSG00000088888 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000137563 ENSG00000175104 ENSG00000164342 PMC5176079__F1 Stress kinases in the modulation of metabolism and energy balance ENSG00000130522 ENSG00000169047 ENSG00000284161 PMC10669090__F2 The influence of risk factors on the formation of peak bone mass ENSG00000167941 PMC7247003__F2 Schematic presentation of key pathways activated in a colorectal cancer cell by three groups of cell membrane receptors ENSG00000182687 ENSG00000069482 ENSG00000138798 ENSG00000166573 ENSG00000168040 ENSG00000146648 PMC7499294__F1 ER stress-induced apoptosis in lesional macrophages and ECs ENSG00000128272 ENSG00000144895 ENSG00000127191 ENSG00000026103 PMC7499294__F2 ER stress-induced inflammation in macrophages and ECs ENSG00000162711 ENSG00000128272 ENSG00000144895 ENSG00000265972 ENSG00000127191 PMC7793297__F13 Runx proteins mediate protective immunity against Leishmania donovani infection by promoting CD40 expression on dendritic cells ENSG00000159216 ENSG00000020633 ENSG00000105656 ENSG00000136869 ENSG00000281857 PMC7209958__F1 Is there a role for tau glutathione transferases in tetrapyrrole metabolism and retrograde signalling in plants? ENSG00000080819 ENSG00000126088 ENSG00000256269 ENSG00000188690 ENSG00000127948 PMC3413046__F2 Integrated functional association analysis of protein and genetic interactions on alanine and aspartate ENSG00000125166 ENSG00000113492 ENSG00000088682 ENSG00000158578 ENSG00000075643 ENSG00000276709 ENSG00000278574 ENSG00000140287 ENSG00000135069 ENSG00000178445 ENSG00000284320 ENSG00000100596 ENSG00000173599 ENSG00000172482 ENSG00000166224 ENSG00000172296 ENSG00000166123 ENSG00000167701 PMC7792222__F5 miRNA-mediated regulation of the BCSCs via targeting the BMI-1 signaling pathway ENSG00000168283 ENSG00000135446 PMC7792222__F4 miRNA-mediated regulation of BCSCs via targeting the PI3K/AKT/mTOR signaling pathway ENSG00000198793 PMC5001910__F3 A guide to immunometabolism for immunologists ENSG00000162711 ENSG00000111537 ENSG00000125538 PMC7263313__F4 Targeting senescent cells to attenuate cardiovascular disease progression ENSG00000164430 ENSG00000105612 PMC6727512__F3 Biosynthesis of AhR ligands from tryptophan metabolism ENSG00000130649 ENSG00000166278 PMC6727512__F1 AhR transcription in mammalian cells and the putative mechanism of AhR activation ENSG00000158290 ENSG00000101751 ENSG00000140505 ENSG00000166169 ENSG00000106546 PMC3660516__F4 Statins Are Associated with Reduced Risk of Esophageal Cancer, Particularly in Patients with Barrett’s Esophagus: A Systematic Review and Meta-Analysis ENSG00000124102 ENSG00000163914 PMC4475795__F1 UPR signaling schematic ENSG00000128272 ENSG00000144895 ENSG00000185591 ENSG00000167182 PMC9032796__F3 Epitranscriptomics of SARS-CoV-2 Infection ENSG00000177606 ENSG00000174197 ENSG00000165819 PMC8231835__F1 MicroRNAs: The Link between the Metabolic Syndrome and Oncogenesis ENSG00000100234 ENSG00000137166 ENSG00000291971 ENSG00000168036 ENSG00000168610 PMC9551057__F8 Excretory/secretory proteins inhibit host immune responses by downregulating the TLR4/NFKB/MAPKs signaling pathway: A possible mechanism of immune evasion in parasitic nematode Haemonchus contortus ENSG00000134982 ENSG00000172936 ENSG00000168610 PMC3043796__F3 Proteins of signaling pathways activated by ET-1 are targets for O-GlcNAc ENSG00000291971 ENSG00000163914 PMC3043796__F1 Signaling pathways activated by endothelin-1 (ET-1) in vascular smooth muscle cells (VSMC) ENSG00000291971 ENSG00000163914 PMC11653592__F1 Main metabolic processes of estrogen ENSG00000086696 ENSG00000108786 ENSG00000140465 PMC3072047__F1 Carbon flux rerouting during Mycobacterium tuberculosis growth arrest ENSG00000137574 ENSG00000026103 PMC11653592__F2 Mechanism of 16Alpha-OHE promoting pulmonary hypertension ENSG00000170365 ENSG00000135218 ENSG00000164736 ENSG00000067057 ENSG00000086991 ENSG00000121058 ENSG00000118971 ENSG00000204217 ENSG00000125968 PMC4854877__F2 Dynamic angiogenic signaling balance and angiogenic switch ENSG00000008710 ENSG00000135218 ENSG00000010810 ENSG00000198670 ENSG00000124181 PMC11653592__F4 4-OHE in pulmonary hypertension; 4-OHEs competitively decrease the activity of 2-OHE2, inhibiting the formation of 2-ME2 ENSG00000198793 ENSG00000079999 PMC9078765__F5 Utilizing Network Pharmacology and Molecular Docking Integrated Surface Plasmon Resonance Technology to Investigate the Potential Targets and Mechanisms of Tripterygium wilfordii against Pulmonary Artery Hypertension ENSG00000112977 ENSG00000142192 ENSG00000111837 PMC11653592__F5 Influence factors of CYPs and HSD17B in PH ENSG00000086696 ENSG00000108786 ENSG00000106546 PMC3875720__F4 Upregulated Genes Encode Key Enzymes in Central Carbon Metabolism.Steps in the glyoxylate cycle (A), gluconeogenesis (B), and oxidative pentose phosphate pathway (C) are shown ENSG00000124253 PMC3295664__F1 Methanol utilization (MUT) pathway in P ENSG00000138356 PMC4112277__F1 The PPP and glycolysis is shown PMC9610969__F2 Molecular Pathways Related to Sulforaphane as Adjuvant Treatment: A Nanomedicine Perspective in Breast Cancer ENSG00000168036 PMC3824052__F2 Smoking-Induced CXCL14 Expression in the Human Airway Epithelium Links Chronic Obstructive Pulmonary Disease to Lung Cancer ENSG00000145824 ENSG00000173702 ENSG00000149418 PMC8779729__F1 Abnormal Iron and Lipid Metabolism Mediated Ferroptosis in Kidney Diseases and Its Therapeutic Potential ENSG00000161905 ENSG00000167468 ENSG00000111684 ENSG00000057663 ENSG00000136381 ENSG00000079999 PMC7813639__F2 Prospects for pharmacological targeting of pseudokinases ENSG00000124102 ENSG00000071575 ENSG00000288499 ENSG00000157764 ENSG00000112964 ENSG00000187266 ENSG00000111816 ENSG00000173334 PMC7140895__F5 Expression of genes in biosynthesis pathway of catechins, theanine, and caffeine under N, P, and K starvation ENSG00000117525 ENSG00000186063 PMC9482317__F2 TGFB signaling in the tumor metabolic microenvironment and targeted therapies ENSG00000145604 ENSG00000198793 PMC12236007__F7 Hypothesis schematic models illustrates that Myh3 regulates the development of porcine intramuscular preadipocytes through the p38 MAPK signaling pathway to affect IMF content ENSG00000245848 ENSG00000084110 ENSG00000123374 ENSG00000026103 PMC9482317__F3 TGFB signaling in the tumor metabolic microenvironment and targeted therapies ENSG00000135218 ENSG00000105329 ENSG00000169710 ENSG00000103257 ENSG00000198911 PMC3275361__F3 Signaling and cross talk of the PTH and Wnt signaling pathways in osteocytes ENSG00000152266 ENSG00000154342 ENSG00000281324 ENSG00000162337 ENSG00000168646 PMC8977630__F3 Novel Synthetic and Natural Therapies for Traumatic Brain Injury ENSG00000134982 ENSG00000189403 ENSG00000172936 ENSG00000171885 PMC6241212__F2 Innate antiviral immune responses during viral infection ENSG00000184979 ENSG00000213928 ENSG00000239732 ENSG00000088888 ENSG00000111537 ENSG00000187608 ENSG00000105397 ENSG00000115415 ENSG00000157601 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC2646278__F5 Pathways of global genome nuclear excision repair (GG-NER) and transcription-coupled nuclear excision repair (TC-NER) ENSG00000292191 ENSG00000100387 ENSG00000277273 ENSG00000134480 ENSG00000136936 PMC4482723__F1 Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease ENSG00000262635 ENSG00000188676 ENSG00000125968 PMC9699386__F5 High Glucose-Induced Cardiomyocyte Damage Involves Interplay between Endothelin ET-1/ETA/ETB Receptor and mTOR Pathway ENSG00000198793 ENSG00000166278 PMC8131923__F3 Adipose tissue plasticity and the pleiotropic roles of BMP signaling PMC8131923__F4 Adipose tissue plasticity and the pleiotropic roles of BMP signaling ENSG00000170365 ENSG00000204217 PMC3163143__F2 Schematic presentation of molecular changes associated with N-Myc amplification in neuroblastoma ENSG00000116990 PMC8710790__F2 Cholesterol‐Associated Steatohepatitis in the Development of NASH ENSG00000138075 ENSG00000015520 ENSG00000141458 ENSG00000120437 ENSG00000143921 PMC3163143__F3 Genomic and non-genomic actions of all-trans retinoic acid (ATRA) ENSG00000145604 ENSG00000142192 ENSG00000101146 ENSG00000137845 PMC8131923__F5 Adipose tissue plasticity and the pleiotropic roles of BMP signaling PMC7365923__F1 Artemisinin-family drugs for cytokine storm in COVID-19 ENSG00000138378 ENSG00000111537 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000106178 PMC3271661__F3 Summary of Kit/Kitl signaling during spermatogenesis ENSG00000157404 ENSG00000134595 ENSG00000256453 PMC9270134__F6 Investigation of Molecular Mechanism of Banxia Xiexin Decoction in Colon Cancer via Network Pharmacology and In Vivo Studies ENSG00000105329 ENSG00000291971 ENSG00000183625 ENSG00000130649 ENSG00000198793 ENSG00000171791 ENSG00000112715 ENSG00000121879 ENSG00000164305 ENSG00000121966 ENSG00000125538 ENSG00000276051 ENSG00000169429 ENSG00000136869 ENSG00000108821 ENSG00000102104 ENSG00000064012 ENSG00000132906 ENSG00000087245 ENSG00000116044 ENSG00000100906 ENSG00000173039 ENSG00000273686 ENSG00000073756 ENSG00000007171 ENSG00000108691 ENSG00000177606 ENSG00000136160 ENSG00000100985 ENSG00000146648 PMC3492913__F1 Diagrammatic representation of BMP signaling pathway ENSG00000107779 ENSG00000170365 ENSG00000204217 PMC6270990__F2 PD-1 action on T-cells ENSG00000134982 PMC338271__F1 HDL enhances NO production by eNOS in vascular endothelium ENSG00000291971 PMC8484365__F2 Endocrine Disruption and Reproductive Disorders: Impacts on Sexually Dimorphic Neuroendocrine Pathways ENSG00000157554 ENSG00000138798 ENSG00000146648 PMC3562404__F2 Biochemical relationships between the CDP-choline pathway of PtdCho synthesis, the degradation of PtdCho, and general phospholipid metabolism in mammals ENSG00000102172 ENSG00000016391 PMC5964648__F3 UPRmt and stem cell regulation ENSG00000215021 ENSG00000128272 ENSG00000096717 PMC7387468__F3 piRNAs related to the epigenetic control of pathways involved in vesicles transport, phagocytosis, demyelination, apoptosis, inflammation, loss of sensation, and pain are differentially expressed in leprosy patient (LP) ENSG00000092445 ENSG00000291431 ENSG00000088256 ENSG00000103522 ENSG00000103550 ENSG00000164305 ENSG00000116209 ENSG00000115616 ENSG00000065135 ENSG00000152315 ENSG00000162594 ENSG00000115486 ENSG00000187097 ENSG00000122012 ENSG00000146352 ENSG00000143473 ENSG00000138380 ENSG00000250571 ENSG00000188803 ENSG00000064012 ENSG00000196689 PMC3319314__F3 APE1 role in DNA base excision repair (BER) ENSG00000132646 PMC6213852__F1 Host metabolism and cytokine induction ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000116688 ENSG00000198793 ENSG00000172936 PMC8126031__F3 Lessons to Learn for Adequate Targeted Therapy Development in Metastatic Colorectal Cancer Patients ENSG00000169554 ENSG00000169047 ENSG00000198793 ENSG00000168610 ENSG00000140443 PMC11956735__F2 Platelet factor 4 (PF4) regulates several immune cells ENSG00000186810 ENSG00000239732 ENSG00000134982 ENSG00000163737 PMC7265888__F2 Annotated KEGG pathway of Endocytosis (A), Peroxisome (B) and MAPK signaling pathways (C) about differentially expressed genes ENSG00000110921 ENSG00000159224 ENSG00000115425 ENSG00000242110 ENSG00000136100 ENSG00000276559 ENSG00000148832 ENSG00000138798 ENSG00000158125 ENSG00000100290 ENSG00000130164 ENSG00000107537 ENSG00000140876 ENSG00000024422 ENSG00000034693 ENSG00000005469 ENSG00000026103 ENSG00000121680 ENSG00000117305 ENSG00000087095 ENSG00000284807 ENSG00000176894 ENSG00000120915 ENSG00000018510 ENSG00000105516 ENSG00000124587 ENSG00000103150 ENSG00000157911 ENSG00000150787 ENSG00000108733 ENSG00000164751 ENSG00000127191 ENSG00000078053 ENSG00000170458 ENSG00000177606 ENSG00000213965 ENSG00000179761 ENSG00000101417 ENSG00000134121 ENSG00000146648 PMC5986633__F7 Selinexor synergizes with dexamethasone to repress mTORC1 signaling and induce multiple myeloma cell death ENSG00000198793 ENSG00000105552 ENSG00000163884 PMC6406952__F2 LncRNAs are mediators of angiogenesis and inflammation in EC ENSG00000253352 ENSG00000112715 ENSG00000168610 PMC7753952__F1 LKB1 in glucose metabolic reprogramming ENSG00000180210 ENSG00000074800 ENSG00000198793 ENSG00000170145 ENSG00000140577 ENSG00000100429 PMC9008213__F2 Two-Faced Role of Autophagy in Endometrial Cancer ENSG00000198793 ENSG00000168038 PMC6389615__F1 Schematic representation of genes involved in osteoclast-poor and osteoclast-rich osteopetrosis ENSG00000173039 PMC5597599__F13 Computational modeling framework ENSG00000138798 PMC11638062__F2 Examples of protein ubiquitination and their roles in ovarian cancer ENSG00000026297 ENSG00000092439 ENSG00000116663 ENSG00000116661 ENSG00000145819 ENSG00000214050 ENSG00000110693 PMC11638062__F3 Examples of protein phosphorylation and their roles in ovarian cancer ENSG00000108395 ENSG00000005882 ENSG00000198793 ENSG00000170145 ENSG00000133124 ENSG00000141568 ENSG00000123374 ENSG00000105647 ENSG00000146648 PMC8495205__F1 Molecular Basis of Prostate Cancer and Natural Products as Potential Chemotherapeutic and Chemopreventive Agents ENSG00000129514 ENSG00000196498 PMC3690158__F1 Wnt signaling pathways ENSG00000291971 ENSG00000168036 PMC6316648__F3 Major mechanisms for hepcidin regulation ENSG00000170365 ENSG00000010704 ENSG00000106327 ENSG00000187045 ENSG00000178752 ENSG00000105697 ENSG00000168610 PMC11823593__F2 Canonical and non‐canonical Wnt signaling pathway ENSG00000169218 ENSG00000281324 ENSG00000162337 ENSG00000100592 ENSG00000134982 ENSG00000133067 ENSG00000163914 ENSG00000177606 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC12086632__F2 The H2S–NO–HNO–TRPA1–CGRP pathway as a crucial element in migraine pathogenesis ENSG00000104321 PMC11357267__F3 Pathways altered in chickens vaccinated with GII ENSG00000128272 ENSG00000144895 ENSG00000159461 ENSG00000165280 ENSG00000127022 ENSG00000100219 ENSG00000171791 ENSG00000127191 ENSG00000135506 PMC7687681__F7 Indirect regulatory functions of miR-128-3p on FOXO4 ENSG00000171246 ENSG00000096717 ENSG00000184481 PMC5983678__F1 GPCRs signaling pathway in HCC ENSG00000163914 ENSG00000198670 PMC10889780__F9 Putative roles of glutathione and AP-1 in the cooperation between VDDs and Nrf2 activators in inducing differentiation of AML cells ENSG00000178573 ENSG00000079999 PMC6036887__F2 Butyrate suppresses colorectal cancer development ENSG00000185591 PMC3763548__F8 Role of the eIF2A/ATF4 signaling pathway in the transcriptional activation of autophagy genes ENSG00000152348 ENSG00000188554 ENSG00000128272 ENSG00000144895 ENSG00000034713 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC9606825__F2 NOTCH1 Signalling: A key pathway for the development of high-risk chronic lymphocytic leukaemia ENSG00000148400 ENSG00000186716 PMC4055861__F2 Base excision repair (BER) pathway ENSG00000109674 ENSG00000292286 ENSG00000105486 ENSG00000139372 ENSG00000129071 ENSG00000140398 PMC11931723__F7 Genomic potential for tryptophan and indole-3-acetic acid (IAA) synthesis in Anza-Borrego isolates of Bradyrhizobium and Methylocaldum ENSG00000158796 PMC8530968__F2 Axon growth and innervation of peripheral targets ENSG00000019991 ENSG00000169071 ENSG00000185483 ENSG00000078804 PMC8261594__F5 Study on the mechanism of the Modified Ginseng-Schisandra Decoction (MGSD) in the treatment of recurrent respiratory tract infection (RRTI) based on network pharmacology ENSG00000133116 ENSG00000162924 PMC12022909__F1 AhR-based drug discovery ENSG00000117525 ENSG00000106546 PMC8261594__F6 Study on the mechanism of the Modified Ginseng-Schisandra Decoction (MGSD) in the treatment of recurrent respiratory tract infection (RRTI) based on network pharmacology ENSG00000111837 ENSG00000164305 PMC12022909__F2 Rewired Yonemitsu MCR: scope and mechanistic insights ENSG00000149311 PMC5338934__F1 Transport pathway of irinotecan.Notes: A prodrug, irinotecan, is moved into hepatic cells by passive effusion ENSG00000172831 ENSG00000134982 ENSG00000023839 ENSG00000262243 PMC7886690__F1 Signaling pathways activated in the unfolded protein response (UPR) ENSG00000128272 ENSG00000127191 PMC7430846__F6 Signaling pathways associated with cold acclimation of two carp species activated in the FoxO signaling pathway ENSG00000171105 ENSG00000135218 ENSG00000138764 ENSG00000005882 ENSG00000113161 ENSG00000096717 ENSG00000146648 ENSG00000140443 PMC7353687__F4 Signal pathways and metabolic pathways involved in abnormal RBP ENSG00000128710 ENSG00000136997 ENSG00000026508 ENSG00000133121 ENSG00000168610 PMC9515729__F2 Beneficial Role of Vitamin D on Endothelial Progenitor Cells (EPCs) in Cardiovascular Diseases ENSG00000162692 PMC4038461__F6 Finding Novel Molecular Connections between Developmental Processes and Disease ENSG00000291971 ENSG00000198793 PMC3340185__F5 A model for the XIAP-regulated RhoGDI SUMOylation signaling pathway in modulation of cell motility ENSG00000150991 ENSG00000171540 PMC8272721__F6 Proposed model of selective anticancer activity of NSLC01 in cancer cells with high NRF2 activation ENSG00000092621 ENSG00000284161 ENSG00000167658 ENSG00000135069 ENSG00000146733 ENSG00000070669 PMC7472841__F3 RIG-I-like receptors (RLRs) antiviral signaling pathway ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000276561 PMC8955204__F1 MicroRNAs in Proteostasis Decline and Protein Aggregation during Brain and Skeletal Muscle Aging ENSG00000158022 ENSG00000116688 ENSG00000198793 ENSG00000141564 ENSG00000108344 PMC3203691__F3 CXCL10/IP-10 in Infectious Diseases Pathogenesis and Potential Therapeutic Implications ENSG00000111537 ENSG00000138755 PMC138693__F2 Phosphoinositide 3-kinase (PI3K) signalling and cancer ENSG00000149311 ENSG00000012048 PMC4502956__F1 TRAIL signaling pathway ENSG00000132906 ENSG00000138794 ENSG00000120868 ENSG00000171791 ENSG00000168040 ENSG00000064012 ENSG00000164305 PMC3095770__F2 Hypothalamic proopiomelanocortin processing and the regulation of energy balance ENSG00000125851 ENSG00000115138 ENSG00000177551 ENSG00000168610 ENSG00000137509 PMC4502956__F2 TRAIL signaling pathway and some points of therapeutic intervention ENSG00000171791 PMC11918095__F7 SiO influences fibrosis in HTMCs via ferroptosis induction ENSG00000151012 ENSG00000167468 ENSG00000086991 PMC9283766__F2 Insights Into the Role of Platelet-Derived Growth Factors: Implications for Parkinson’s Disease Pathogenesis and Treatment ENSG00000177606 ENSG00000168036 PMC11907553__F1 The KRAS signaling pathway ENSG00000183735 ENSG00000002330 ENSG00000070831 ENSG00000198793 PMC10418793__F6 Major pathways involved in retinal inflammation ENSG00000104856 ENSG00000198793 ENSG00000177606 ENSG00000168610 PMC3270265__F5 Regulation of cell death by glucose metabolism ENSG00000002330 ENSG00000198793 ENSG00000168040 PMC11212664__F8 Suppression of MyD88 disturbs gut microbiota and activates the NLR pathway and hence fails to ameliorate DSS-induced colitis ENSG00000167207 ENSG00000172936 ENSG00000106100 PMC3270265__F3 Glucose metabolism in cancer cells ENSG00000180210 ENSG00000074800 ENSG00000078237 PMC9102069__F2 Immunogenic Cell Death, DAMPs and Prothymosin A as a Putative Anticancer Immune Response Biomarker ENSG00000168404 PMC8402745__F4 Risk Factors Associated with the Clinical Outcomes of COVID-19 and Its Variants in the Context of Cytokine Storm and Therapeutics/Vaccine Development Challenges ENSG00000196843 ENSG00000115415 ENSG00000168610 PMC6400555__F3 Models for the roles of Scribble in organizing molecular interactomes involved in synaptogenesis, epithelial polarity, and adhesion, and growth regulation ENSG00000083857 ENSG00000274429 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC11974557__F1 Adipose Tissue Inflammation and Insulin Resistance Mediated by TLR4 Activation and Adipokines ENSG00000169047 ENSG00000132693 PMC8402745__F2 Risk Factors Associated with the Clinical Outcomes of COVID-19 and Its Variants in the Context of Cytokine Storm and Therapeutics/Vaccine Development Challenges ENSG00000197635 ENSG00000130234 ENSG00000184012 PMC8402745__F3 Risk Factors Associated with the Clinical Outcomes of COVID-19 and Its Variants in the Context of Cytokine Storm and Therapeutics/Vaccine Development Challenges ENSG00000162711 ENSG00000009724 ENSG00000189403 ENSG00000172936 ENSG00000136869 PMC10216084__F8 TRPV4 and TRPM8 signalling pathways relevant to the present study ENSG00000039537 ENSG00000137672 ENSG00000138741 PMC2391280__F1 A signaling pathway AKTing up in schizophrenia ENSG00000184845 ENSG00000149295 PMC3216694__F1 Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors ENSG00000163914 ENSG00000173599 ENSG00000198670 PMC7212589__F8 Mechanistic working model of EVI5 in controlling Emi1 accumulation or TGF- B/Smad signaling pathway: MiR-486-5p regulates EVI5 expression via Emi1 or TGFB/Smad signaling in NSCLC ENSG00000087245 ENSG00000134982 ENSG00000170558 ENSG00000145386 PMC7997242__F4 CD226 downregulation ENSG00000291971 ENSG00000150637 PMC4923112__F3 Classification pathway for primary lymphedema ENSG00000176692 ENSG00000183287 ENSG00000198793 ENSG00000037280 ENSG00000179348 ENSG00000138160 ENSG00000150630 PMC1952166__F1 Signaling cascades required for TCR-mediated integrin activation ENSG00000213658 ENSG00000070831 ENSG00000113263 ENSG00000124181 PMC6059364__F2 Crosstalk of Notch with p53 and p63 in cancer growth control ENSG00000002330 ENSG00000099860 ENSG00000284194 ENSG00000136826 PMC4856261__F6 NUDT2 Disruption Elevates Diadenosine Tetraphosphate (Ap4A) and Down-Regulates Immune Response and Cancer Promotion Genes ENSG00000291603 ENSG00000244687 ENSG00000118503 ENSG00000102871 ENSG00000138798 ENSG00000196591 ENSG00000197943 ENSG00000172936 ENSG00000157625 ENSG00000168040 ENSG00000150455 ENSG00000198286 PMC4856261__F4 NUDT2 Disruption Elevates Diadenosine Tetraphosphate (Ap4A) and Down-Regulates Immune Response and Cancer Promotion Genes ENSG00000111537 ENSG00000105397 ENSG00000089127 ENSG00000115415 ENSG00000185201 ENSG00000185885 ENSG00000142089 ENSG00000171791 ENSG00000125347 ENSG00000230034 PMC3084988__F2 TLR structure and signaling ENSG00000150455 ENSG00000164342 PMC4856261__F5 NUDT2 Disruption Elevates Diadenosine Tetraphosphate (Ap4A) and Down-Regulates Immune Response and Cancer Promotion Genes ENSG00000137275 ENSG00000131323 ENSG00000168040 ENSG00000175104 ENSG00000127191 ENSG00000121060 PMC9619213__F2 Follistatin-like protein 3 in human non-tumor pathophysiologies and cancers ENSG00000087245 ENSG00000135218 ENSG00000125538 ENSG00000070404 ENSG00000168036 ENSG00000100985 ENSG00000096717 ENSG00000148848 PMC7955704__F2 EGFRex20ins TKI resistance ENSG00000105810 ENSG00000146648 ENSG00000178568 PMC7608616__F3 Targeting BCL-2 in B-cell malignancies and overcoming therapeutic resistance PMC11203611__F4 Diagram of endocannabinoid biosynthesis and mode of action of the endocannabinoid system within a neuron ENSG00000275723 ENSG00000117480 ENSG00000196689 PMC5599995__F6 Proposed model by which mesenchymal stromal cell (MSC) derived soluble PD‐1 ligands modulate the activation status and effector function of CD4+ T cells PMC5027689__F1 Fanconi anemia (FA) DNA damage repair pathway ENSG00000164053 ENSG00000101751 ENSG00000154920 ENSG00000077152 ENSG00000188827 ENSG00000181544 ENSG00000197774 ENSG00000187790 ENSG00000115392 ENSG00000130997 ENSG00000187741 ENSG00000112039 ENSG00000158169 ENSG00000139618 ENSG00000131944 ENSG00000175054 ENSG00000144554 ENSG00000197299 ENSG00000122008 ENSG00000122512 PMC6747410__F1 Signaling pathway of DNAM-1 receptor ENSG00000010810 ENSG00000197943 ENSG00000141968 PMC3023986__F2 Wnt Signaling as a Therapeutic Target for Bone Diseases ENSG00000138795 ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000291971 ENSG00000134982 ENSG00000168036 ENSG00000167074 ENSG00000104332 PMC9377071__F7 Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer’s disease ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC3422444__F1 AIDing antibody diversity by error-prone mismatch repair ENSG00000132646 ENSG00000095002 PMC3422444__F2 AIDing antibody diversity by error-prone mismatch repair ENSG00000188486 ENSG00000095002 ENSG00000112130 ENSG00000122512 PMC3923659__F3 Structural Pathway of Interleukin 1 (IL-1) Initiated Signaling Reveals Mechanisms of Oncogenic Mutations and SNPs in Inflammation and Cancer ENSG00000162889 ENSG00000197971 ENSG00000125538 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000115594 PMC5076853__F1 More to life than NFKB in TNFR1 signaling ENSG00000137275 ENSG00000102871 ENSG00000157625 ENSG00000127191 PMC5749242__F5 The two fates of C3b generated in the retina ENSG00000274619 ENSG00000000971 PMC11056704__F8 Graphic illustration for role of oestrogen‐induced exosomal SNHG17‐CCL13‐CCR2‐M2 macrophage axis in ovarian cancer ENSG00000181374 ENSG00000121807 PMC3923659__F2 Structural Pathway of Interleukin 1 (IL-1) Initiated Signaling Reveals Mechanisms of Oncogenic Mutations and SNPs in Inflammation and Cancer ENSG00000162889 ENSG00000115008 ENSG00000111537 ENSG00000197971 ENSG00000125538 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000115594 PMC6617682__F1 The mechanism of exosomal miRNAs loading ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC4937511__F9 Candidate SCI biomarker input for Systems Biology and pathway network analysis ENSG00000182718 ENSG00000125166 ENSG00000167658 ENSG00000169710 PMC3405917__F4 EMT in fibrosis ENSG00000169554 ENSG00000170558 PMC9412305__F4 The Innate Immune Response during the Human Papillomavirus Life Cycle ENSG00000026103 PMC9412305__F5 The Innate Immune Response during the Human Papillomavirus Life Cycle ENSG00000183735 ENSG00000164430 ENSG00000088888 PMC7085234__F1 RREB1-involved in MAPK signaling pathway ENSG00000146648 ENSG00000124782 PMC7085234__F2 RREB1 regulates different target genes in different cancers ENSG00000167772 ENSG00000116584 ENSG00000124782 PMC3722486__F9 Proposed role of Foxg1 in CM development ENSG00000138795 ENSG00000115507 ENSG00000163132 ENSG00000134245 ENSG00000176165 ENSG00000251493 PMC4524513__F1 Tendon Mechanobiology: Current Knowledge and Future Research Opportunities ENSG00000110711 ENSG00000105664 ENSG00000171540 PMC3405917__F1 Wound repair and fibrosis ENSG00000105329 ENSG00000137033 ENSG00000145777 ENSG00000166090 PMC6841741__F3 Ingenuity pathway analysis of the significantly altered miRNA found in the follicular fluid showing that 12 of these miRNA were related to the genes involved in the Inflammatory disease pathway ENSG00000160789 ENSG00000152749 ENSG00000119737 ENSG00000178573 ENSG00000181619 ENSG00000177606 ENSG00000164400 ENSG00000065559 ENSG00000125650 PMC5725281__F9 Cardioprotective effect of CAPE-oNO2 ENSG00000096717 ENSG00000106459 PMC7052362__F2 Tumor-associated macrophages (TAMs) in promoting tumor progression and related mechanisms ENSG00000198053 ENSG00000104972 ENSG00000142512 ENSG00000272398 ENSG00000168610 PMC6384614__F5 Biosynthetic pathway for the capuramycin-type nucleoside antibiotics ENSG00000142192 ENSG00000204021 PMC6841741__F2 Ingenuity pathway analysis of the significantly altered miRNA found in the follicular fluid showing that 12 of these miRNA were related to the genes involved in the Organismal Injury and Abnormalities, Reproductive System Disease pathway ENSG00000169291 ENSG00000204335 ENSG00000119737 ENSG00000096088 ENSG00000178980 ENSG00000177685 ENSG00000118997 ENSG00000186994 ENSG00000205362 ENSG00000184999 PMC9553103__F2 ATP and Adenosine Metabolism in Cancer: Exploitation for Therapeutic Gain ENSG00000196839 ENSG00000291814 ENSG00000197594 PMC9055718__F6 Anti-inflammatory effects of lavender and eucalyptus essential oils on the in vitro cell culture model of bladder pain syndrome using T24 cells ENSG00000226275 ENSG00000125538 PMC5931372__F1 Clonal evolution mechanisms in NT5C2 mutant relapsed acute lymphoblastic leukemia ENSG00000137364 PMC8632384__F11 Network Pharmacology-Based Study on Irritable Bowel Syndrome Prevention and Treatment Utilizing Shenling Baizhu Powder ENSG00000177606 ENSG00000007908 PMC7576987__F5 Working model of 2,3-DCPE in colon cancer cells ENSG00000149311 ENSG00000175054 PMC6006682__F4 Representative coverage of Calvin-Benson cycle enzyme PMC8324677__F1 Stress kinases in the development of liver steatosis and hepatocellular carcinoma ENSG00000105550 ENSG00000169047 ENSG00000161533 ENSG00000113790 PMC4237616__F2 Survival tree analysis of significant SNPs associated with NSCLC survival identified from the single SNP analysis (q<0.10) in our initial cohort ENSG00000156076 ENSG00000111186 ENSG00000168646 ENSG00000168772 PMC8949960__F1 Cancer-Related Cachexia: The Vicious Circle between Inflammatory Cytokines, Skeletal Muscle, Lipid Metabolism and the Possible Role of Physical Training ENSG00000198793 ENSG00000164327 ENSG00000140443 PMC8949960__F2 Cancer-Related Cachexia: The Vicious Circle between Inflammatory Cytokines, Skeletal Muscle, Lipid Metabolism and the Possible Role of Physical Training ENSG00000198793 ENSG00000140443 PMC4965740__F9 Computational discovery of Epstein-Barr virus targeted human genes and signalling pathways ENSG00000157933 ENSG00000117425 ENSG00000168036 ENSG00000133997 ENSG00000170365 ENSG00000106571 ENSG00000166813 ENSG00000184634 ENSG00000125686 ENSG00000139549 ENSG00000163501 ENSG00000169375 ENSG00000064309 ENSG00000157540 ENSG00000005339 ENSG00000165115 ENSG00000169439 ENSG00000150459 ENSG00000180447 ENSG00000164161 ENSG00000141480 ENSG00000144857 ENSG00000164690 ENSG00000132964 ENSG00000128602 PMC3080795__F2 Scheme for CCM including main pathways - glycolysis/gluconeogenesis, penthaphosphate pathway, citrate cycle, overflow pathway ENSG00000122966 ENSG00000172005 ENSG00000153574 ENSG00000094975 PMC7460634__F2 Semaphorins in adipogenesis ENSG00000075213 ENSG00000010319 PMC4965740__F8 Computational discovery of Epstein-Barr virus targeted human genes and signalling pathways ENSG00000135547 ENSG00000196591 ENSG00000196782 ENSG00000105647 ENSG00000198681 ENSG00000135441 ENSG00000170365 ENSG00000144485 ENSG00000143801 ENSG00000018236 ENSG00000168214 ENSG00000074181 ENSG00000184384 ENSG00000128917 ENSG00000078747 ENSG00000022267 ENSG00000169375 ENSG00000100603 ENSG00000109670 ENSG00000100811 ENSG00000138795 ENSG00000142192 ENSG00000148400 ENSG00000109320 ENSG00000184916 ENSG00000135144 ENSG00000168610 ENSG00000090932 ENSG00000139352 ENSG00000164105 ENSG00000071564 ENSG00000145604 ENSG00000065526 ENSG00000273529 ENSG00000133961 ENSG00000114315 PMC8380049__F2 Novel Experimental Therapies for Treatment of Pulmonary Arterial Hypertension ENSG00000170365 ENSG00000204217 ENSG00000163217 PMC6637138__F7 Innate immune response activation in BRCA2-deficient cells ENSG00000164430 ENSG00000115415 ENSG00000142166 ENSG00000139618 PMC4264220__F1 Schematic representation of homocysteine metabolism and intersection with glutathione (GSH) production and folate cycle PMC3309495__F2 Pathway analysis of altered metabolites upon paroxetine treatment ENSG00000197635 ENSG00000111713 PMC4155643__F1 Pathways of sphingolipid degradation and synthesis ENSG00000167769 ENSG00000118402 ENSG00000151726 ENSG00000119915 ENSG00000165996 ENSG00000143418 ENSG00000139624 ENSG00000063176 ENSG00000223802 ENSG00000172292 ENSG00000072210 ENSG00000154227 ENSG00000170522 ENSG00000074696 ENSG00000206527 ENSG00000188921 ENSG00000066322 ENSG00000197977 ENSG00000197142 ENSG00000188611 ENSG00000078124 ENSG00000164398 ENSG00000123983 PMC7348939__F1 Fundamental aging mechanisms that contribute to sarcopenia ENSG00000116688 ENSG00000171109 PMC7348939__F2 Possible molecular mechanisms of cellular senescence in skeletal muscle cells ENSG00000154342 ENSG00000135446 ENSG00000123374 PMC6028526__F2 Insulin biosynthesis and secretion ENSG00000139515 ENSG00000182759 ENSG00000157005 PMC3943598__F1 Molecular mechanisms in Carney complex (CNC) and McCune-Albright syndrome (MAS): Receptor activation (ligand binding) makes GsA to exchange GDP to GTP, GsA is then freed from the BetaG dimer and activates adenyl cyclase (AC) ENSG00000168036 ENSG00000087460 PMC3056800__F7 Deep sequencing of the Camellia sinensis transcriptome revealed candidate genes for major metabolic pathways of tea-specific compounds ENSG00000186063 ENSG00000145321 ENSG00000119125 PMC3639322__F3A Time-dependent network analysis reveals molecular targets underlying the development of diet-induced obesity and non-alcoholic steatohepatitis ENSG00000078747 ENSG00000095321 ENSG00000187288 ENSG00000076555 ENSG00000132170 PMC3681733__F2 Reprogramming Neutral Lipid Metabolism in Mouse Dendritic Leucocytes Hosting Live Leishmania amazonensis Amastigotes ENSG00000011198 ENSG00000131446 ENSG00000168282 ENSG00000107798 ENSG00000173599 ENSG00000285482 ENSG00000198670 ENSG00000079435 ENSG00000105223 PMC3257556__F2 Known components of the PCP signalling pathway and related cellular functions ENSG00000163637 ENSG00000004975 ENSG00000107404 ENSG00000070831 ENSG00000143878 ENSG00000164066 ENSG00000173218 ENSG00000075275 ENSG00000010361 ENSG00000104290 ENSG00000112655 ENSG00000067900 PMC5813884__F5 Nitrogen regulation of the GAAC pathway ENSG00000144895 ENSG00000099804 PMC5813884__F6 Influence of the RTG pathway on nitrogen metabolism ENSG00000011143 PMC2813229__F4 Pathway analysis result showing 18 differentially expressed proteins following 50% PH can be sorted into the c-myc pathway ENSG00000117054 ENSG00000213619 ENSG00000117707 ENSG00000140464 PMC6151665__F8 Mechanism of emodin to inhibit IAV replication and IAV viral pneumonia ENSG00000181019 ENSG00000136869 ENSG00000175104 PMC5088520__F1 Path2enet: generation of human pathway-derived networks in an expression specific context ENSG00000004975 ENSG00000196782 ENSG00000143801 ENSG00000163840 ENSG00000184384 ENSG00000128917 ENSG00000283780 ENSG00000205155 ENSG00000124232 ENSG00000196498 ENSG00000100603 ENSG00000107404 ENSG00000005339 ENSG00000178498 ENSG00000184916 ENSG00000175029 ENSG00000135144 ENSG00000090932 ENSG00000110042 ENSG00000106003 ENSG00000091073 ENSG00000273529 ENSG00000133961 ENSG00000161202 ENSG00000114315 ENSG00000114166 PMC5088520__F2 Pathway-expression-networks produced for B cell CD19+ (top), T cell CD8+ (bottom left) and T cell CD4+ (bottom right) based on the transformation of the NOTCH Signaling Pathway done with Path2enet ENSG00000177455 ENSG00000107404 ENSG00000163840 ENSG00000100060 ENSG00000161202 ENSG00000133961 ENSG00000175029 ENSG00000106003 PMC8835043__F1 Decoding the Phosphatase Code: Regulation of Cell Proliferation by Calcineurin ENSG00000135446 ENSG00000123374 PMC1371031__F4 Model on Bcr effects on Beta-catenin ENSG00000186716 ENSG00000136997 ENSG00000168036 PMC6509867__F8 Annotated functions of the extracted pathway network ENSG00000069482 ENSG00000213658 ENSG00000250366 ENSG00000146648 PMC6948307__F5 Schematic diagram of IL-1B signaling pathway in MSC adhesion to HUVECs ENSG00000178860 PMC3210925__F5A Mapping photoautotrophic metabolism with isotopically nonstationary 13C flux analysis ENSG00000261701 ENSG00000184207 PMC6635885__F2 Activation modes of the NLRP3 inflammasome and the regulatory mechanism of CVDs ENSG00000162711 ENSG00000150782 ENSG00000125538 ENSG00000136869 ENSG00000198626 ENSG00000265972 ENSG00000036828 PMC2683106__F5 Promoting cell proliferation and repressing differentiation ENSG00000138764 ENSG00000221818 ENSG00000185155 ENSG00000198793 ENSG00000164093 PMC6368065__F7 Hematopoietic deletion of COX-2 increases adiposity and AT inflammation in obesity ENSG00000262406 ENSG00000174804 ENSG00000161202 PMC6220476__F1 Circular RNA ITCH and 0043256 act as miRNA sponges to regulate the expression of ITCH ENSG00000078747 ENSG00000168036 PMC8269088__F1 Challenges with Approved Targeted Therapies against Recurrent Mutations in CLL: A Place for New Actionable Targets ENSG00000174125 ENSG00000198793 ENSG00000168610 ENSG00000010671 ENSG00000095585 ENSG00000187554 ENSG00000010810 ENSG00000186716 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC8269088__F2 Challenges with Approved Targeted Therapies against Recurrent Mutations in CLL: A Place for New Actionable Targets ENSG00000128917 ENSG00000090932 ENSG00000109670 PMC7555769__F2 Noncanonical HH signaling pathway ENSG00000198793 ENSG00000163914 ENSG00000128602 PMC6117282__F2 Gene networks involved in a) 'developmental disorder, ophthalmic disease, organismal injury and abnormalities' (score = 41) and b) 'cell-to-cell signaling and interaction, nervous system development and function, inflammatory disease' (score = 21) ENSG00000168807 ENSG00000221944 ENSG00000142192 ENSG00000147535 ENSG00000078668 ENSG00000197429 ENSG00000069329 ENSG00000132478 ENSG00000164305 ENSG00000147262 ENSG00000111537 ENSG00000138613 ENSG00000198838 ENSG00000177606 ENSG00000150907 ENSG00000059145 ENSG00000100580 ENSG00000124098 ENSG00000089737 ENSG00000292003 ENSG00000271425 ENSG00000140932 PMC7555769__F3 SMO in cancer ENSG00000087245 ENSG00000163914 ENSG00000118816 ENSG00000171791 ENSG00000100985 ENSG00000128602 PMC4496218__F9 Pentacyclic triterpene natural product, ursolic acid and its prodrug US597 inhibit targets within cell adhesion pathway and prevent cancer metastasis ENSG00000162692 PMC11731776__F2 Figure compares normal and G3BP1-depleted or inhibited senescent cells ENSG00000168610 PMC7555769__F1 Canonical Hedgehog (HH) signaling pathway ENSG00000103241 ENSG00000171791 ENSG00000128602 PMC3535180__F1 Elevated immune-inflammatory signaling in mood disorders: a new therapeutic target? ENSG00000125538 ENSG00000132693 PMC11731776__F3 Figure illustrates the DNA damage response pathway leading to cellular senescence ENSG00000149311 ENSG00000175054 ENSG00000285109 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC6058063__F1 Immunoglobulin G4-related disease (IgG4-RD) and immune pathways to therapy. Naïve B cells are activated by exposure to antigens ENSG00000177455 ENSG00000139193 ENSG00000186716 ENSG00000103522 PMC8882273__F7 Selective inhibitor of the NLRP3 inflammasome as a potential therapeutic approach for neuroprotection in a transgenic mouse model of Huntington’s disease ENSG00000162711 ENSG00000125538 ENSG00000197386 PMC5542228__F5 Quantitative proteomics profiling reveals activation of mTOR pathway in trastuzumab resistance ENSG00000140992 ENSG00000198793 ENSG00000164327 ENSG00000108443 ENSG00000281877 ENSG00000141564 ENSG00000167965 ENSG00000162302 ENSG00000121879 ENSG00000187840 ENSG00000175634 ENSG00000177189 ENSG00000162409 ENSG00000135932 PMC9324353__F2 Chaperone System in Breast Cancer: Roles and Therapeutic Prospects of the Molecular Chaperones Hsp27, Hsp60, Hsp70, and Hsp90 ENSG00000135446 ENSG00000198793 ENSG00000171791 ENSG00000168040 ENSG00000146648 ENSG00000026103 PMC12146343__F2 Signals from the gut microbiota lead to the differentiation of T cells into various subtypes ENSG00000163235 ENSG00000198793 ENSG00000107485 ENSG00000172936 ENSG00000136869 ENSG00000049768 PMC12146343__F1 Gut microbiota involved in the development of AIH ENSG00000198793 ENSG00000136869 ENSG00000106546 PMC6605322__F7 Scheme summarizing the protective effects of sevoflurane on lipopolysaccharide-induced inflammation and apoptosis by suppressing the activation of the miR-27a/TLR4/MyD88/NFKB signaling pathway ENSG00000172936 ENSG00000136869 PMC8579454__F3 Lipid-induced S-palmitoylation as a Vital Regulator of Cell Signaling and Disease Development ENSG00000135218 ENSG00000010810 ENSG00000169710 ENSG00000172936 ENSG00000136869 ENSG00000023041 PMC4127586__F2 A model of Src homology 2B1 regulation of leptin signaling ENSG00000178188 ENSG00000169047 ENSG00000168610 PMC6692341__F5 Control of fruit biochemical composition ENSG00000173992 ENSG00000147869 ENSG00000078124 PMC4699913__F4 Phosphoproteomic Profiling Reveals Epstein-Barr Virus Protein Kinase Integration of DNA Damage Response and Mitotic Signaling ENSG00000124535 ENSG00000134438 ENSG00000155827 ENSG00000262826 ENSG00000198793 ENSG00000033800 ENSG00000183765 ENSG00000149311 ENSG00000175054 ENSG00000137807 ENSG00000111602 ENSG00000084676 ENSG00000144554 ENSG00000132646 ENSG00000116096 ENSG00000140464 ENSG00000111642 PMC6192992__F6 Scheme depicting role of HORMAD1 in DSB signaling and repair ENSG00000149311 ENSG00000012048 ENSG00000112130 PMC9711961__F8 Paeoniflorin Inhibits LPS-Induced Activation of Splenic CD4+ T Lymphocytes and Relieves Pathological Symptoms in MRL/lpr Mice by Suppressing IRAK1 Signaling ENSG00000136869 ENSG00000184216 PMC6764628__F5 Relationships of the top differentially expressed genes within the top GSEA gene sets ENSG00000169908 ENSG00000159388 ENSG00000148926 ENSG00000122877 ENSG00000099860 ENSG00000162772 ENSG00000073756 ENSG00000166592 ENSG00000164949 PMC9693644__F1 Epha2 Receptor Blockers Involved in Cerebral Malaria from Taraxacum officinale, Tinospora cordifolia, Rosmarinus officinalis and Ocimum basilicum: A Computational Approach ENSG00000142627 ENSG00000108691 ENSG00000226275 ENSG00000132478 PMC5426657__F7 Protective effects and functional mechanisms of Lactobacillus gasseri SBT2055 against oxidative stress ENSG00000181019 PMC11392660__F3 Immunologic mechanisms following decellularized matrix transplantation involve several crucial steps ENSG00000239732 ENSG00000198793 ENSG00000172936 PMC2989646__F4 The involvement of zinc metalloproteinases in AB metabolism ENSG00000143537 ENSG00000149451 ENSG00000142192 ENSG00000117298 ENSG00000168615 ENSG00000119912 ENSG00000137845 PMC8367322__F1 LncRNA BANCR in Human Cancers: An Updated Review ENSG00000134982 ENSG00000168036 PMC6186432__F2 Apoptotic membrane blebbing through DR5/Casp-3/ROCK1 signaling pathway ENSG00000168040 ENSG00000182541 PMC7642512__F2 CD40 induces activation of autophagy signaling pathway ENSG00000177169 ENSG00000198793 ENSG00000144848 ENSG00000132478 ENSG00000145782 ENSG00000057663 PMC8367322__F4 LncRNA BANCR in Human Cancers: An Updated Review ENSG00000170558 ENSG00000115904 PMC8349595__F4 Nutrition, One-Carbon Metabolism and Arsenic Methylation ENSG00000214435 ENSG00000291507 ENSG00000173638 ENSG00000173599 ENSG00000116984 ENSG00000133027 PMC11817496__F9 The apoptosis signaling pathway triggered by PM2 ENSG00000132906 ENSG00000110711 ENSG00000102871 ENSG00000171759 ENSG00000168040 ENSG00000127191 ENSG00000064012 ENSG00000164305 PMC3096731__F1 Eph receptor and mTOR pathway crosstalk: implications for cancer ENSG00000198793 PMC4240271__F1 Post-translational regulation of TGFB receptor and Smad signaling ENSG00000135655 ENSG00000023734 ENSG00000157933 ENSG00000095739 ENSG00000078747 ENSG00000198742 ENSG00000084072 ENSG00000026508 ENSG00000175104 ENSG00000123124 PMC6075432__F14 Sodium fluoride induces autophagy in mammalian mice spleen ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC9404585__F1 Microglial TYROBP/DAP12 in Alzheimer’s disease: Transduction of physiological and pathological signals across TREM2 ENSG00000011600 ENSG00000291971 ENSG00000198793 PMC6803322__F8 Diagram illustrating the IL-6 signaling pathway triggered by the binding of IL-6 and its receptor complex resulting in JAK2/STAT3 activation ENSG00000168610 PMC7010923__F2 Proposed model for signaling pathway of fibrosis in MDC1A ENSG00000130234 ENSG00000198793 PMC9469193__F8 Antigastric Cancer Effect of Triptolide is Associated With H19/NFKB/FLIP Axis ENSG00000102871 PMC7822116__F3 Can Metformin Exert as an Active Drug on Endothelial Dysfunction in Diabetic Subjects? ENSG00000005421 ENSG00000142082 PMC5945496__F6 Mutant p53 tunes the NRF2-dependent antioxidant response to support survival of cancer cells ENSG00000157764 ENSG00000151012 ENSG00000175793 ENSG00000023909 ENSG00000079999 PMC12136072__F2 Signaling pathway of BMP4 as well as activators and inhibitors of BMP4 cellular signaling ENSG00000137834 ENSG00000095739 ENSG00000198742 ENSG00000168487 PMC12136072__F3 Recent Advances in the Delivery of Bone Morphogenetic Proteins for Targeting Glioma: An Updated Review ENSG00000170365 ENSG00000168283 ENSG00000106571 ENSG00000118503 ENSG00000148400 ENSG00000074181 ENSG00000164690 ENSG00000128602 ENSG00000168610 PMC8536203__F9 Proteomic Landscape of Extracellular Vesicles for Diffuse Large B-Cell Lymphoma Subtyping ENSG00000070190 ENSG00000104365 ENSG00000105369 ENSG00000282905 ENSG00000007312 ENSG00000269335 ENSG00000115904 ENSG00000110651 ENSG00000185885 ENSG00000152689 ENSG00000213341 ENSG00000169032 ENSG00000274513 ENSG00000141968 ENSG00000010671 ENSG00000177455 ENSG00000095585 ENSG00000072694 ENSG00000166501 ENSG00000145321 ENSG00000197943 ENSG00000155629 ENSG00000198286 PMC5468628__F1 GRN and SBN circuits ENSG00000138083 ENSG00000143013 ENSG00000146469 ENSG00000163666 ENSG00000149557 ENSG00000163064 ENSG00000117707 ENSG00000164690 ENSG00000134595 ENSG00000168505 ENSG00000176165 ENSG00000125084 PMC3649098__F3 Signaling pathway for zinc prevention of atherosclerosis in monocytes/macrophages and vascular endothelial cells: a proposed hypothesis ENSG00000162692 ENSG00000132693 PMC8520942__F1 Recent Advances of WEE1 Inhibitors and Statins in Cancers With p53 Mutations ENSG00000167468 ENSG00000123374 PMC5710670__F1 Clinically relevant inhibitors of the isoprenoid biosynthetic pathway (IBP) (a) Statins inhibit HMG CoA reductase, consequently reducing the entire IBP ENSG00000160752 ENSG00000070831 ENSG00000197429 PMC5987911__F1 Logical regulatory network graphs for a mammalian cell cycle network (PN1) and a melanoma-related pathway network (PN2), modified from and 1 in Qian and Dougherty, respectively ENSG00000138029 ENSG00000163993 ENSG00000117399 PMC9319949__F11 Repositioning Linagliptin for the Mitigation of Cadmium-Induced Testicular Dysfunction in Rats: Targeting HMGB1/TLR4/NLRP3 Axis and Autophagy ENSG00000162711 ENSG00000197635 ENSG00000198793 ENSG00000284099 ENSG00000189403 ENSG00000136869 ENSG00000171791 PMC5854428__F1 Viral manipulation of STAT3: Evade, exploit, and injure ENSG00000196090 ENSG00000112964 ENSG00000081237 ENSG00000291971 ENSG00000198793 ENSG00000103522 ENSG00000105639 ENSG00000168610 ENSG00000145623 ENSG00000105397 ENSG00000122756 ENSG00000146648 ENSG00000158050 ENSG00000168685 ENSG00000130726 PMC5854428__F2 Viral manipulation of STAT3: Evade, exploit, and injure ENSG00000173599 ENSG00000168610 ENSG00000130726 PMC2957472__F3 Helicobacter pylori: gastric cancer and beyond ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC12110123__F9 Ginsenoside CK can enhance the expression of CD69, CD80, and CD86, stimulate the NFKB and AP-1 inflammatory signaling pathway, and induce macrophages to secrete iNOS and TNFA to enhance inflammatory response ENSG00000085117 PMC4715579__F6 Top biological network generated by Ingenuity Pathway Analysis for differentially expressed proteins of (A) ALDH+/CD44+CD24−, (B) ALDH+/CD49f-EpCAM+ and (C) CD44+CD24−/CD49f-EpCAM+ ENSG00000115484 ENSG00000105835 ENSG00000060138 ENSG00000130638 ENSG00000089157 ENSG00000148843 ENSG00000117707 ENSG00000146457 ENSG00000186575 ENSG00000115524 ENSG00000126247 ENSG00000196365 ENSG00000137055 PMC6042724__F3 Whole exome sequencing identifies MRVI1 as a susceptibility gene for moyamoya syndrome in neurofibromatosis type 1 ENSG00000147649 ENSG00000133107 ENSG00000175793 ENSG00000116741 ENSG00000196712 PMC12110123__F5 Anticancer Mechanisms of Ginsenoside Compound K: A Review ENSG00000087245 ENSG00000100985 ENSG00000121966 PMC4397421__F1 Translocations affecting the NFKB activation pathway ENSG00000110330 ENSG00000172936 ENSG00000150787 ENSG00000175104 ENSG00000198286 PMC12110123__F4 Ginsenoside CK inhibits the expression of AKT/mTOR/p70S6K1 proteins and blocks the PI3K/AKT/mTOR signaling pathway in cancer cells, reducing the expression of MMP2 and MMP9 proteases ENSG00000087245 ENSG00000198793 ENSG00000100985 PMC6476865__F2 The PI3K-Akt-mTOR signaling by bioactive sphingolipids ENSG00000100422 ENSG00000170989 ENSG00000213694 ENSG00000267534 PMC3011892__F4 Cell cycle pathway containing Treponema denticola differentially regulated genes in calvarial bone compared with sham-infected controls at P ≤ 0.05, adapted from Pathway Express and using the Kyoto Encyclopedia of Genes and Genomes nomenclature ENSG00000132646 ENSG00000123374 ENSG00000277273 ENSG00000276876 PMC5182153__F1 Insulin Receptor Signaling Pathway Targeted by Surgery-Responsive microRNAs ENSG00000131473 ENSG00000171105 ENSG00000002330 ENSG00000110395 ENSG00000010810 ENSG00000106070 ENSG00000198793 ENSG00000105656 ENSG00000220205 ENSG00000079435 PMC3011892__F5 Molecular characterization of Treponema denticola infection-induced bone and soft tissue transcriptional profiles ENSG00000144063 ENSG00000132646 ENSG00000115942 ENSG00000123374 ENSG00000277273 PMC9692683__F2 SARS-CoV-2-Induced Amyloidgenesis: Not One, but Three Hypotheses for Cerebral COVID-19 Outcomes ENSG00000162711 ENSG00000131095 ENSG00000132693 PMC3011892__F1 Molecular characterization of Treponema denticola infection-induced bone and soft tissue transcriptional profiles ENSG00000081237 ENSG00000134982 ENSG00000197471 ENSG00000163599 ENSG00000150637 PMC5567867__F1 Major steps in the HR pathway in budding yeast ENSG00000175054 ENSG00000051180 PMC3163259__F1 Wnt/Beta-catenin signalling in the absence and presence of Wnt stimulus ENSG00000087095 ENSG00000155011 ENSG00000050165 ENSG00000104371 ENSG00000168036 PMC7705761__F4 Identification of key gene networks controlling organic acid and sugar metabolism during watermelon fruit development by integrating metabolic phenotypes and gene expression profiles ENSG00000112977 ENSG00000062485 PMC5910271__F2 Redox Regulation of Circadian Molecular Clock in Chronic Airway Diseases ENSG00000096717 ENSG00000142082 PMC8657568__F1 Plant Dehydrins: Expression, Regulatory Networks, and Protective Roles in Plants Challenged by Abiotic Stress ENSG00000164151 ENSG00000069956 PMC8043250__F1 Top left, in red: NK cells recognize tumor targets that lack MHC, as this prevents the inhibitory response mediated by KIR ENSG00000153283 ENSG00000181847 ENSG00000197943 ENSG00000109943 ENSG00000231179 ENSG00000204520 ENSG00000146648 ENSG00000150637 ENSG00000141968 ENSG00000101290 PMC3747619__F2 Key reactions involved in the sphingolipid metabolic pathway ENSG00000100422 ENSG00000119537 ENSG00000148154 PMC9655901__F3 Interplay between Autophagy and Herpes Simplex Virus Type 1: ICP34.5, One of the Main Actors ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000132646 ENSG00000108561 ENSG00000079999 PMC6321280__F3 Many molecules regulate apoptosis and Hippo-YAP signaling pathway ENSG00000129474 ENSG00000087510 ENSG00000130545 ENSG00000078747 ENSG00000263528 ENSG00000140464 ENSG00000169435 ENSG00000109670 PMC5080657__F2 Genetics of immune-mediated disorders ENSG00000197747 ENSG00000117228 ENSG00000100450 ENSG00000087074 ENSG00000179820 ENSG00000235162 ENSG00000162654 ENSG00000137441 ENSG00000164691 ENSG00000115415 ENSG00000156587 ENSG00000142405 ENSG00000213145 PMC2763943__F2 Nox proteins in signal transduction ENSG00000162889 ENSG00000102871 ENSG00000149269 PMC4694912__F3 MicroRNA biomarker identification for pediatric acute myeloid leukemia based on a novel bioinformatics model ENSG00000149311 ENSG00000127586 ENSG00000108055 ENSG00000132646 ENSG00000132383 ENSG00000286140 ENSG00000062485 ENSG00000141446 PMC7082279__F1 Resistant mechanisms of TKIs in target therapies of NSCLC ENSG00000019582 ENSG00000141753 ENSG00000146678 ENSG00000146648 ENSG00000086730 ENSG00000143924 ENSG00000140443 PMC6321280__F1 Components of the Hippo-YAP signaling pathway ENSG00000150457 ENSG00000131023 PMC9158463__F1 Understanding How Physical Exercise Improves Alzheimer’s Disease: Cholinergic and Monoaminergic Systems ENSG00000142192 ENSG00000096717 PMC7029504__F7 FOXO signaling pathway enriched in KEGG ENSG00000145604 ENSG00000149311 ENSG00000087095 ENSG00000171105 ENSG00000127528 ENSG00000123374 ENSG00000145782 ENSG00000168610 PMC7484684__F5 DE miRNA/mRNA interaction network constructed and visualized using Cytoscape software ENSG00000281324 ENSG00000160408 ENSG00000146477 ENSG00000104332 ENSG00000166501 ENSG00000170921 ENSG00000102921 ENSG00000001626 ENSG00000171174 ENSG00000162512 ENSG00000064393 ENSG00000156564 ENSG00000157837 ENSG00000133048 ENSG00000106780 ENSG00000084070 ENSG00000167702 ENSG00000285383 ENSG00000103061 ENSG00000196792 ENSG00000274749 ENSG00000026751 ENSG00000139154 ENSG00000198948 ENSG00000140848 ENSG00000124209 ENSG00000173085 ENSG00000087274 PMC4050496__F2 Notch: Architect, Landscaper, and Guardian of the Intestine ENSG00000140564 ENSG00000138798 PMC3835661__F1 Cell Death in Heart Disease ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC8263688__F8 IL-17 signaling pathway plays a key role in laryngeal squamous cell carcinoma with ethnic specificity ENSG00000102871 ENSG00000130522 ENSG00000166484 ENSG00000135341 ENSG00000163702 ENSG00000150782 ENSG00000172216 ENSG00000066044 ENSG00000149968 ENSG00000108688 ENSG00000163734 ENSG00000169429 ENSG00000164400 ENSG00000157625 ENSG00000064012 ENSG00000100906 ENSG00000109320 ENSG00000213341 ENSG00000112116 ENSG00000111537 ENSG00000118503 ENSG00000131323 ENSG00000100985 ENSG00000175104 ENSG00000089053 PMC7458396__F2 Cellular signalling pathways mediated by the constitutive activation of US28 ENSG00000163914 ENSG00000168036 ENSG00000168610 PMC4100111__F3 Bioinformatics analysis by String ENSG00000291835 ENSG00000167671 ENSG00000111057 ENSG00000168925 ENSG00000182446 ENSG00000123992 ENSG00000165280 ENSG00000153002 ENSG00000158516 PMC3546894__F1 Cytokine regulation of immune response cell phases through gender specific pathways ENSG00000111537 PMC5152733__F1 Lymph node fibroblastic reticular cells in health and disease ENSG00000099866 ENSG00000077150 ENSG00000165682 ENSG00000162493 ENSG00000137077 ENSG00000111321 ENSG00000140545 ENSG00000162692 ENSG00000121966 PMC5963715__F3 PI3K/AKT/mTOR signaling pathway ENSG00000198793 PMC5352059__F4 Differentiated regulation of immune-response related genes between LUAD and LUSC subtypes of lung cancers ENSG00000154589 ENSG00000137275 ENSG00000109320 ENSG00000198851 ENSG00000163599 ENSG00000043462 ENSG00000150455 ENSG00000121879 ENSG00000143387 ENSG00000150782 ENSG00000111537 ENSG00000213658 ENSG00000170458 ENSG00000135446 ENSG00000167941 ENSG00000149269 ENSG00000010810 ENSG00000172005 ENSG00000158825 ENSG00000113520 ENSG00000164400 ENSG00000172936 ENSG00000160293 ENSG00000198286 PMC9099959__F4 Identifying Protein Features and Pathways Responsible for Toxicity Using Machine Learning and Tox21: Implications for Predictive Toxicology ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000106546 PMC9099959__F5 Identifying Protein Features and Pathways Responsible for Toxicity Using Machine Learning and Tox21: Implications for Predictive Toxicology ENSG00000102871 ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000127191 ENSG00000276561 ENSG00000184216 ENSG00000106546 PMC9099959__F3 Identifying Protein Features and Pathways Responsible for Toxicity Using Machine Learning and Tox21: Implications for Predictive Toxicology ENSG00000012048 ENSG00000140505 ENSG00000171759 ENSG00000175104 ENSG00000140465 ENSG00000106546 PMC11732762__F2 CD28 signaling in FOXP3 expression and the effects of belatacept ENSG00000134982 ENSG00000198793 ENSG00000173039 ENSG00000049768 PMC8839664__F6 Metabolism and Health Effects of Rare Sugars in a CACO-2/HepG2 Coculture Model ENSG00000138030 ENSG00000113161 ENSG00000169710 ENSG00000265972 ENSG00000096717 ENSG00000158125 PMC7056524__F1 In normal B cells, Mir-15/16 target Bcl2 ENSG00000002330 ENSG00000171791 PMC5174080__F1 Innate and adaptive immune responses induced by Avian leukosis virus (ALV) PMC4905167__F1 Novel targets for ATM-deficient malignancies ENSG00000143799 ENSG00000149311 ENSG00000144554 ENSG00000138385 ENSG00000139618 PMC10417163__F2 Signaling pathways play an essential role in organizing the Golgi apparatus and maintaining neuronal polarity during neurogenesis ENSG00000113384 ENSG00000180957 ENSG00000143761 ENSG00000173406 PMC2597811__F1 Molecular Genetics of Colorectal Cancer: An Overview ENSG00000134982 ENSG00000168036 ENSG00000095002 ENSG00000122512 PMC6376477__F11 Molecular mechanism of circHMGCS1: regulating miR-503-5p to control IGF signaling by functioning as a ceRNA ENSG00000115419 ENSG00000140443 PMC3010690__F2 Zinc metalloprotease activity in APP processing ENSG00000142192 ENSG00000119912 PMC8987592__F2 TGFB/Smad Signaling Pathway in Tubulointerstitial Fibrosis PMC8987592__F1 TGFB/Smad Signaling Pathway in Tubulointerstitial Fibrosis PMC7544055__F5 Toll like Receptor signalling by Prevotella histicola activates alternative NFKB signalling in Cystic Fibrosis bronchial epithelial cells compared to P. aeruginosa ENSG00000104856 ENSG00000187554 ENSG00000136869 PMC2855642__F2 Glycosylation of Alpha-dystroglycan ENSG00000009830 ENSG00000130714 ENSG00000181027 PMC5116673__F3 Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with Idiopathic Pulmonary Fibrosis ENSG00000107779 ENSG00000070193 ENSG00000105329 ENSG00000138772 ENSG00000129422 ENSG00000135903 ENSG00000005102 ENSG00000091409 ENSG00000106511 ENSG00000089225 ENSG00000072571 ENSG00000066468 ENSG00000159200 ENSG00000170365 ENSG00000292234 ENSG00000115457 ENSG00000148082 ENSG00000112378 ENSG00000180875 ENSG00000164690 ENSG00000179348 ENSG00000143995 PMC2612755__F5 A theoretical pancreatic endocrine tumor cell, smooth muscle cell (pericyte) or endothelial cell demonstrating the sites and mechanism of action of novel agents for the management of metastatic PETs ENSG00000122025 ENSG00000198793 ENSG00000146648 PMC8518663__F1 Manipulation of auxin signalling by plant viruses ENSG00000047410 ENSG00000113558 PMC8518663__F2 Manipulation of auxin signalling by plant viruses ENSG00000047410 ENSG00000113558 PMC3904723__F7 Putative functions of the differentially expressed proteins in metabolic processes of rice grain development at high temperatures ENSG00000159224 PMC7448212__F6 Mechanism by which MCL attenuates the inflammatory response of NRK-52E cells ENSG00000162711 ENSG00000125538 PMC10177107__F1 Different signaling pathways and epigenetic mechanisms that have been deregulated during TNBC progression and growth, contributing to stemness ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000198793 ENSG00000139618 PMC9108976__F2 Cellular and Developmental Roles of Cullins, Neddylation, and the COP9 Signalosome in Dictyostelium discoideum ENSG00000039537 ENSG00000044090 ENSG00000111530 ENSG00000159593 ENSG00000285246 ENSG00000184182 ENSG00000171209 ENSG00000112659 ENSG00000166266 ENSG00000043093 ENSG00000158290 ENSG00000100387 ENSG00000139842 PMC3958149__F2 Example of Janus kinase (JAK) inhibitors blocking cytokine signalling ENSG00000115415 ENSG00000105639 PMC7905801__F1 IDO- and cell-mediated immunosuppression ENSG00000134982 PMC6501234__F9 Proposed molecular mechanism for LPS-induced downregulation of StAR expression and progesterone production in pGL ENSG00000141448 ENSG00000285109 PMC6071399__F3 Analyzing Toll-like receptor signaling pathway by QIAGEN, KEGG and wikipathway websites and drawing pathway by Pathvisio software ENSG00000074266 PMC7890234__F1 Activation of unfolded protein response ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC6387699__F1 Effect of Oxidative Stress on the Estrogen-NOS-NO-KCa Channel Pathway in Uteroplacental Dysfunction: Its Implication in Pregnancy Complications ENSG00000138336 ENSG00000145321 PMC10217562__F5 KEGG diagram of plant hormone signal transduction pathway under salt stress ENSG00000110934 ENSG00000221818 PMC5371797__F2A Non-Canonical Roles of Dengue Virus Non-Structural Proteins ENSG00000183735 ENSG00000088888 ENSG00000062485 PMC3617338__F1 Multivalency and conditional regulation at the cell surface ENSG00000131446 ENSG00000168282 ENSG00000152127 PMC2584013__F25 ER stress and ROS in NAFLD/NASH ENSG00000128272 ENSG00000127191 PMC3438932__F7 The role of dimeric TIR platform for the inhibition and activation of MyD88 signaling pathway ENSG00000134070 ENSG00000172936 ENSG00000184216 PMC10891858__F1 Investigating the Role of Non-Coding RNA in Non-Alcoholic Fatty Liver Disease ENSG00000042832 ENSG00000198793 ENSG00000026103 PMC7054754__F2 Core signalling pathways maintaining human pluripotent stem cells (hPSCs) ENSG00000281324 ENSG00000162337 ENSG00000136997 ENSG00000156574 ENSG00000168036 ENSG00000140443 PMC10891858__F4 Major signaling pathways by ncRNA in NAFLD/NASH as discussed in the text (Created with BioRender ENSG00000198793 PMC7054754__F1 An overview of class IA PI3K signalling ENSG00000131473 ENSG00000124102 ENSG00000177169 ENSG00000065911 ENSG00000101751 ENSG00000198382 ENSG00000284161 ENSG00000112561 ENSG00000167658 ENSG00000265972 ENSG00000171791 ENSG00000101557 ENSG00000128272 ENSG00000136997 ENSG00000179632 ENSG00000159399 ENSG00000084774 PMC2584013__F23 TNF-induced and ROS-dependent events in target cells: the role of JNK activation in mediating cell death ENSG00000102871 ENSG00000120868 ENSG00000168040 ENSG00000127191 PMC4918704__F1 TLR4 (toll-like receptor 4) signaling: MyD88 (myeloid differentiation primary response 88)-dependent and MyD88-independent pathways mediate TLR4 signaling ENSG00000243414 ENSG00000108691 ENSG00000081041 ENSG00000170458 ENSG00000169429 ENSG00000172936 ENSG00000136869 ENSG00000124875 ENSG00000150455 ENSG00000127666 ENSG00000115009 PMC4546439__F1 Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened ENSG00000106571 ENSG00000128602 PMC4546439__F2 Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened ENSG00000149311 ENSG00000087245 ENSG00000171791 ENSG00000100985 ENSG00000026103 PMC10478475__F8 Hypothesized mechanism by which Ex-4 reduces tau hyperphosphorylation via Wnt/Beta-catenin/NeuroD1 signalling in T2D models ENSG00000134982 ENSG00000168036 PMC12215756__F10 NCC cellular metabolism is coupled to a developmental program ENSG00000124216 ENSG00000019549 ENSG00000187140 ENSG00000115419 ENSG00000125084 PMC9433570__F9 Macrophage polarization regulates intervertebral disc degeneration by modulating cell proliferation, inflammation mediator secretion, and extracellular matrix metabolism ENSG00000133048 ENSG00000134057 ENSG00000123728 ENSG00000125538 ENSG00000112984 ENSG00000171848 ENSG00000163734 ENSG00000124875 ENSG00000135373 ENSG00000117399 ENSG00000163815 ENSG00000105825 PMC5428311__F3 Summary of the major global regulatory responses of S ENSG00000066336 ENSG00000150787 PMC4438467__F1 Mitochondrial cholesterol trafficking in regulation of macrophage sterol metabolism ENSG00000130164 ENSG00000135929 PMC8187249__F2 Protected complex of biofactors and antioxidants improved growth performance and modulated the immunometabolic phenotype of broiler chickens undergoing early life stress ENSG00000162594 ENSG00000150455 ENSG00000096717 ENSG00000127191 ENSG00000168610 PMC6491684__F8 Schematic representation that hypothesizes the effects of ethanol (A), THC and/or OEA (B) on neurotrophic signaling pathway via AKT and ERK1/2, and its neurogenic response in the hippocampus ENSG00000185652 ENSG00000148773 ENSG00000077279 ENSG00000164305 PMC3030733__F1 Interventions in nuclear factor erythroid 2-related factor 2-Kelch-like ECH-associated protein 1 signaling pathway ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC3308892__F4 ER stress-associated miR-346 induction ENSG00000100219 PMC7530341__F6 Proposed gestational age-dependent changes in placental TRP metabolic pathways ENSG00000168003 ENSG00000146477 ENSG00000150787 ENSG00000103257 ENSG00000171097 ENSG00000116096 PMC5460696__F1 Schematic of androgen synthesis illustrating the classic androgen pathway (gray boxes) and the steroids of the 11-oxygenated androgen pathway (black boxes) ENSG00000176387 PMC5491785__F7 Schema of the putative mechanisms by which myostatin may influence the function of bone cells ENSG00000131196 PMC8278082__F7 Naa10p and IKKA interaction regulates EMT in oral squamous cell carcinoma via TGF‐B1/Smad pathway ENSG00000105329 PMC10039534__F2 Unleashing the potential of combining FGFR inhibitor and immune checkpoint blockade for FGF/FGFR signaling in tumor microenvironment ENSG00000169245 ENSG00000111537 ENSG00000069869 ENSG00000273686 ENSG00000049768 PMC4520755__F1 Canonical Notch signalling pathway and relevant pharmacological inhibitors under development in cancer ENSG00000112576 ENSG00000283780 ENSG00000128917 ENSG00000198435 ENSG00000136997 ENSG00000184916 ENSG00000090932 ENSG00000124762 PMC4520755__F2 Canonical HH-signalling pathway and pharmacological inhibitors targeting this pathway that are under ongoing development as anticancer therapies ENSG00000168283 ENSG00000106571 ENSG00000136997 ENSG00000139549 ENSG00000128602 PMC4520755__F3 Canonical Wnt signalling pathway and pharmacological inhibitors under investigation in cancer ENSG00000281324 ENSG00000137673 ENSG00000162337 ENSG00000135100 ENSG00000134982 ENSG00000026508 ENSG00000168036 ENSG00000132170 PMC3531707__F3 PERK signaling under virus attack ENSG00000128272 ENSG00000100219 PMC7456554__F3 Toll-like receptor (TLR) pathways deregulated in systemic sclerosis (SSc) ENSG00000183735 ENSG00000170458 ENSG00000172005 ENSG00000172936 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC9095362__F2 Cancer Stem Cell-Derived Exosomes in Cancer Progression ENSG00000186340 ENSG00000292234 ENSG00000065361 ENSG00000168610 ENSG00000132693 PMC7996755__F2 Targeting Nrf2 signaling pathway in chemoprotection ENSG00000229314 ENSG00000079999 PMC9095362__F3 Cancer Stem Cell-Derived Exosomes in Cancer Progression ENSG00000170558 PMC7996755__F3 Nrf2 signaling in mediating DOX resistance of cancer cells ENSG00000026508 ENSG00000198670 PMC9095362__F1 Cancer Stem Cell-Derived Exosomes in Cancer Progression ENSG00000065357 ENSG00000130402 PMC7996755__F1 Schematic presentation of Nrf2 signaling pathway ENSG00000100387 ENSG00000023909 ENSG00000079999 PMC9656931__F10 Protective Effect of the Polysaccharides from Taraxacum mongolicum Leaf by Modulating the p53 Signaling Pathway in H22 Tumor-Bearing Mice ENSG00000177455 PMC10510267__F8 MCL’s protection against PD-related peritoneal fibrosis ENSG00000105329 PMC7876405__F1 p38MAPK-MK2 axis is activated in response to diverse inflammatory stimuli ENSG00000137033 ENSG00000102871 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000175104 ENSG00000127191 ENSG00000164342 PMC5058662__F3 RNA-Seq analysis reveals new evidence for inflammation-related changes in aged kidney ENSG00000117020 ENSG00000125538 ENSG00000177606 ENSG00000136869 ENSG00000277943 PMC5923345__F1 NF2/merlin-Hippo signaling cascade dysregulation ENSG00000129474 ENSG00000126016 ENSG00000186575 ENSG00000144560 ENSG00000136997 ENSG00000026508 ENSG00000150457 ENSG00000187772 ENSG00000131023 ENSG00000101333 PMC5923345__F2 Signaling cascades and molecules that affect Hippo pathway signaling and YAP1/TAZ activation in MM cells ENSG00000198793 ENSG00000163914 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC6016729__F6 Where Hematopoietic Stem Cells Live: The Bone Marrow Niche ENSG00000100697 ENSG00000168036 PMC4613848__F1 RASSF1A/LATS1/CDK2 pathway upon fork stalling ENSG00000175054 ENSG00000164053 ENSG00000165392 ENSG00000197299 ENSG00000123374 ENSG00000051180 ENSG00000131023 ENSG00000139618 PMC6604204__F11 Schematic model of how minocycline may inhibit TNF-Alpha-induced cell fusion ENSG00000149968 ENSG00000291971 ENSG00000100985 PMC8607372__F3 Cytosolic and nuclear recognition of virus and viral evasion ENSG00000183735 ENSG00000088888 ENSG00000121060 ENSG00000141569 PMC4613848__F2 RASSF1A regulation of the Hippo pathway in response to DNA damage ENSG00000149311 ENSG00000175054 ENSG00000123374 ENSG00000131023 PMC3087924__F1 Autophagy in macrophages ENSG00000198793 ENSG00000168610 PMC8607372__F4 Cytosolic and nuclear recognition of virus and viral evasion ENSG00000183735 ENSG00000164430 ENSG00000163565 PMC10951359__F6 CGRP-induced anxiety-like behavior through epigenetic regulation of the p-HP1G–KLF11–MAOB–dopamine pathway PMC2464594__F4 Oct-4 Targets in the Wnt Signalling Pathway ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000100387 ENSG00000134982 ENSG00000147869 ENSG00000113558 ENSG00000196470 ENSG00000115718 ENSG00000132170 PMC5270432__F4 rno-miRNA-mRNA network affecting VEGF signaling pathway based on the first global prediction.VEGF: Vascular endothelial growth factor ENSG00000166869 ENSG00000132906 ENSG00000162889 ENSG00000117215 ENSG00000102908 ENSG00000105647 ENSG00000127472 ENSG00000089159 ENSG00000114738 ENSG00000187980 ENSG00000221823 ENSG00000063176 ENSG00000185386 ENSG00000188257 ENSG00000243708 ENSG00000129946 ENSG00000276870 ENSG00000166501 ENSG00000285485 PMC5791370__F4 Proteomic analysis of the genes in Xllp08 and wild-type E ENSG00000108849 ENSG00000073578 ENSG00000122966 ENSG00000117118 ENSG00000172005 PMC9572368__F2 Ubiquitin–Proteasome System (UPS) and Viral Infection in Plants ENSG00000188554 ENSG00000100387 ENSG00000113558 ENSG00000166278 PMC8607372__F1 Cytosolic and nuclear recognition of virus and viral evasion ENSG00000168872 ENSG00000162711 ENSG00000183735 ENSG00000152778 ENSG00000088888 ENSG00000185745 ENSG00000121060 ENSG00000141569 PMC8607372__F2 Cytosolic and nuclear recognition of virus and viral evasion ENSG00000183735 ENSG00000164430 ENSG00000163565 ENSG00000174953 ENSG00000172936 PMC5238783__F2 miR-22 services as onco-miRNA to promote tumor malignant transformation ENSG00000118971 PMC7343820__F8 AChR antibody-induced effects on myotubes expressing AChR clusters ENSG00000134569 ENSG00000030304 PMC6945172__F5 Schematic of fatty acid Beta-oxidation, oxidative stress response and cholesterol absorption processes in the enterocytes of mouse ENSG00000138075 ENSG00000135218 ENSG00000138823 ENSG00000015520 ENSG00000120437 ENSG00000143921 PMC2698322__F4 Key proteins regulated by PKB that are involved in metabolism (yellow); cell cycle progression (green); cellular growth (red); cell survival and apoptosis (blue); angiogenesis (orange) and neurological processes (purple) ENSG00000002330 PMC4589385__F1 Bioinformatics Analyses of the Role of Vascular Endothelial Growth Factor in Patients with Non-Small Cell Lung Cancer ENSG00000132906 ENSG00000162889 ENSG00000002330 ENSG00000070831 ENSG00000291971 ENSG00000169032 ENSG00000112715 ENSG00000073756 ENSG00000089159 ENSG00000117020 ENSG00000063176 ENSG00000129946 ENSG00000128052 ENSG00000166501 ENSG00000124181 PMC2698322__F3 Complex relationship between PI3-K, mTOR and PKB signalling ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC4632950__F3 Molecular complexes involved in the calcium signaling pathways responded to BPS and WEX treatments ENSG00000198363 PMC8032655__F6 Cell cycle at high altitudes (The purple boxes represent enzymes or genes, green box represent down-regulated) ENSG00000171105 ENSG00000138798 PMC9260044__F2 Novel Insight of CircRNAs in Cervical Cancer: Potential Biomarkers and Therapeutic Target ENSG00000125398 ENSG00000135457 PMC4632950__F2 Molecular complexes involved in the integrin-linked kinase signaling pathway responded to BPS and WEX treatments ENSG00000198793 ENSG00000071051 PMC8874522__F2 Cerebellar and Striatal Implications in Autism Spectrum Disorders: From Clinical Observations to Animal Models ENSG00000184845 ENSG00000149295 PMC7671463__F3 Cell signalling influences immune response and resistance to immunotherapy ENSG00000111537 ENSG00000198793 ENSG00000168036 PMC7359798__F2 Immune Sensing Mechanisms that Discriminate Self from Altered Self and Foreign Nucleic Acids ENSG00000162711 ENSG00000109606 ENSG00000174885 ENSG00000174953 ENSG00000172795 ENSG00000183735 ENSG00000152778 ENSG00000088888 ENSG00000204010 ENSG00000120280 ENSG00000067248 ENSG00000168404 ENSG00000164342 ENSG00000026297 ENSG00000124256 ENSG00000185745 ENSG00000114127 ENSG00000168040 ENSG00000127191 ENSG00000276561 ENSG00000172936 ENSG00000185792 ENSG00000135828 ENSG00000175104 ENSG00000285379 PMC9331395__F6 Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD+ Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase ENSG00000143799 ENSG00000291803 ENSG00000170430 ENSG00000095002 ENSG00000227345 ENSG00000122512 PMC7359798__F3 Immune Sensing Mechanisms that Discriminate Self from Altered Self and Foreign Nucleic Acids ENSG00000162711 ENSG00000164062 ENSG00000187796 ENSG00000163568 ENSG00000163565 ENSG00000276561 ENSG00000128394 ENSG00000105223 ENSG00000166428 ENSG00000183735 ENSG00000239732 ENSG00000105612 ENSG00000164430 ENSG00000088888 ENSG00000120280 ENSG00000189403 ENSG00000172936 ENSG00000175104 ENSG00000247315 PMC6953032__F3 JNK pathways controlling contradictory responses in neurons ENSG00000169474 ENSG00000164627 ENSG00000162772 PMC11626976__F6 Interaction role between TRIM family and p53 signaling pathway in GI cancer ENSG00000213186 ENSG00000113595 ENSG00000119401 ENSG00000119283 ENSG00000122779 ENSG00000121060 ENSG00000130726 PMC11626976__F4 Interaction role between TRIM family and STAT3 signaling pathway in GI cancer ENSG00000087245 ENSG00000106785 ENSG00000137699 ENSG00000183718 ENSG00000100985 ENSG00000166436 ENSG00000168610 PMC11626976__F5 The TRIM family in the TGFB signaling pathway in GI cancer ENSG00000275718 ENSG00000132481 ENSG00000121060 PMC11626976__F2 Interaction role between TRIM family and Akt signaling pathway in GI cancer ENSG00000213186 ENSG00000166326 ENSG00000106785 ENSG00000119401 ENSG00000122779 PMC11626976__F3 Interaction role between TRIM family and Wnt/Beta-catenin signaling pathway in GI cancer ENSG00000154370 ENSG00000137673 ENSG00000134982 ENSG00000119401 ENSG00000142453 ENSG00000137699 ENSG00000168036 ENSG00000122779 ENSG00000162722 ENSG00000130726 PMC3670242__F1 JAK-STAT pathway and hematopoietic stem cells from the JAK2 V617F perspective ENSG00000004455 ENSG00000168610 PMC8310348__F1 Immunity and Viral Infections: Modulating Antiviral Response via CRISPR–Cas Systems ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000163568 ENSG00000125538 ENSG00000163565 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC6543669__F2 LncRNA/pseudogene–miRNA–mRNA ceRNA network in CRC ENSG00000153823 ENSG00000134982 ENSG00000119969 ENSG00000166025 ENSG00000171791 ENSG00000120256 ENSG00000137558 ENSG00000140511 ENSG00000220205 ENSG00000077782 ENSG00000198910 ENSG00000169851 ENSG00000143995 ENSG00000164176 ENSG00000101695 ENSG00000111962 ENSG00000123989 ENSG00000140285 ENSG00000164093 ENSG00000149294 ENSG00000175592 ENSG00000115657 ENSG00000159167 ENSG00000003137 ENSG00000111913 ENSG00000137941 ENSG00000117016 ENSG00000143515 ENSG00000101955 ENSG00000149577 ENSG00000105784 ENSG00000177732 ENSG00000059588 ENSG00000101265 ENSG00000162407 ENSG00000137449 ENSG00000134363 ENSG00000138411 ENSG00000139343 ENSG00000065320 ENSG00000018408 ENSG00000168077 ENSG00000160183 ENSG00000157570 ENSG00000182983 ENSG00000134504 ENSG00000047634 ENSG00000197343 ENSG00000066468 ENSG00000291606 ENSG00000196411 ENSG00000117020 ENSG00000104154 ENSG00000115956 ENSG00000160445 ENSG00000117091 ENSG00000187288 ENSG00000184371 PMC7445374__F2 Contact system in disease states ENSG00000288512 ENSG00000175899 ENSG00000244731 ENSG00000166278 ENSG00000122194 ENSG00000182326 PMC3245550__F2 Arf Family G Proteins and their regulators: roles in membrane transport, development and disease ENSG00000107862 ENSG00000120805 ENSG00000143761 ENSG00000168374 ENSG00000134287 ENSG00000153317 PMC7998362__F7 Four identified pathways responsible for P ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000171759 ENSG00000188690 ENSG00000150787 ENSG00000107165 ENSG00000116096 ENSG00000158125 PMC3527886__F2 Network of biglycan signaling in osteoblast differentiation and stabilizing role of biglycan in skeletal muscle ENSG00000154342 ENSG00000170365 ENSG00000168036 PMC7818013__F1 DNA double-strand break repair pathway choice: a new focus on 53BP1 ENSG00000149311 ENSG00000163961 ENSG00000080345 ENSG00000082212 ENSG00000112130 PMC8783345__F4 Extracellular vesicles produced by the human commensal gut bacterium Bacteroides thetaiotaomicron affect host immune pathways in a cell‐type specific manner that are altered in inflammatory bowel disease ENSG00000173039 PMC8783345__F5 Extracellular vesicles produced by the human commensal gut bacterium Bacteroides thetaiotaomicron affect host immune pathways in a cell‐type specific manner that are altered in inflammatory bowel disease ENSG00000172005 ENSG00000115718 PMC6769485__F2 Anti-apoptotic and cell survival activities of some HSPs in cancer ENSG00000006712 ENSG00000026103 PMC6769485__F3 HSP90 functions as a mediator of many oncogenic and signaling pathways ENSG00000070831 ENSG00000291971 ENSG00000134982 ENSG00000168036 ENSG00000171791 ENSG00000168040 ENSG00000168610 ENSG00000146648 ENSG00000026103 PMC6580974__F9 Network diagram displaying the IAV-dependent phosphorylation changes in the actin cytoskeleton and focal adhesion KEGG pathways ENSG00000180210 ENSG00000002330 ENSG00000134982 ENSG00000173599 ENSG00000177606 ENSG00000203710 ENSG00000089159 PMC12055712__F8 Model illustrating the regulatory role of Roraa in circadian rhythms and metabolism ENSG00000029153 ENSG00000165030 ENSG00000132326 ENSG00000167074 PMC8783345__F6 Extracellular vesicles produced by the human commensal gut bacterium Bacteroides thetaiotaomicron affect host immune pathways in a cell‐type specific manner that are altered in inflammatory bowel disease ENSG00000172005 ENSG00000127948 PMC8783345__F7 Extracellular vesicles produced by the human commensal gut bacterium Bacteroides thetaiotaomicron affect host immune pathways in a cell‐type specific manner that are altered in inflammatory bowel disease ENSG00000172005 ENSG00000080823 PMC10530670__F5 Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Modulate Apoptosis, TNF Alpha and Interferon Gamma Response Gene mRNA Expression in T Lymphocytes ENSG00000149311 ENSG00000100290 ENSG00000142192 ENSG00000168040 ENSG00000084774 PMC6354076__F1 Sirtuins and metabolism ENSG00000187531 ENSG00000124523 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000089163 ENSG00000283100 PMC6354076__F2 Sirtuins and B lymphocytes ENSG00000110448 ENSG00000186716 ENSG00000145321 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000089163 ENSG00000283100 PMC6329746__F6 Molecular signaling pathways relevant to the resistance to MAPK pathway inhibitors ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC7920740__F3 Description of antioxidant enzyme system regulation via the Keap1-Nrf2-ARE pathway ENSG00000178573 ENSG00000079999 PMC3294214__F2 Signaling pathways regulating epithelial immune response in nematode epidermal (a) and intestinal (b) cells, adapted from Tan and Shapira ENSG00000118515 PMC7818013__F3 DNA double-strand break repair pathway choice: a new focus on 53BP1 ENSG00000012048 ENSG00000163961 ENSG00000080345 ENSG00000051180 ENSG00000112130 PMC6471594__F2 Cilia-dependent regulation of the Hedgehog signaling pathway ENSG00000128602 PMC6471594__F3 Cilia-dependent regulation of PDGFRA signaling pathway ENSG00000124102 ENSG00000109083 ENSG00000134853 PMC7906909__F8 Inhibition of PFKFB3 induces cell death and synergistically enhances chemosensitivity in endometrial cancer ENSG00000180210 ENSG00000198793 ENSG00000051180 PMC7762141__F2 Host immune response against P ENSG00000239732 ENSG00000125538 ENSG00000172936 ENSG00000150455 ENSG00000106100 ENSG00000112486 ENSG00000062485 PMC7045519__F3 Epigenetic regulators in ferroptosis ENSG00000163930 ENSG00000092470 ENSG00000066044 ENSG00000134824 PMC3136937__F4 Identification and Analysis of Signaling Networks Potentially Involved in Breast Carcinoma Metastasis to the Brain ENSG00000122566 ENSG00000008438 ENSG00000172667 ENSG00000134086 ENSG00000124614 ENSG00000230989 ENSG00000106993 ENSG00000170855 ENSG00000149273 ENSG00000198125 PMC3847901__F2 Rat sarcoma viral oncogene homolog (RAS) activation converts normal keratinocytes to an initiated phenotype through a series of potentially reversible autocrine signals ENSG00000081041 ENSG00000291971 ENSG00000163739 ENSG00000010810 ENSG00000138798 ENSG00000172936 ENSG00000124875 ENSG00000100985 ENSG00000146648 PMC6621562__F1 Ubiquitin regulations on mTOR signaling components ENSG00000100150 ENSG00000177169 ENSG00000114388 ENSG00000198793 ENSG00000169047 ENSG00000155792 ENSG00000112561 ENSG00000164327 ENSG00000081913 ENSG00000130147 ENSG00000198198 ENSG00000145979 ENSG00000118515 ENSG00000239282 PMC3847901__F3 Divergent roles of myeloid differentiation factor 88 (MyD88) in colon carcinogenesis ENSG00000162711 ENSG00000174885 ENSG00000172936 PMC7045519__F1 Known function of organelles in ferroptosis ENSG00000128272 ENSG00000151012 ENSG00000137275 ENSG00000143761 ENSG00000167468 ENSG00000115271 ENSG00000168610 ENSG00000128965 PMC4180336__F2 Bile acid biosynthetic pathways ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC5111231__F2 Hypothetical pathway regulating the response of skeletal slow twitch muscle to endurance training: myogenesis, fuel usage, and myosin fiber type change ENSG00000172005 ENSG00000140943 ENSG00000129152 ENSG00000081189 PMC4132015__F5 Notch, TGF-Beta, Wnt, Hedgehog, JAK-STAT and MAPK pathways ENSG00000049323 ENSG00000087095 ENSG00000134982 ENSG00000156574 ENSG00000134363 ENSG00000137193 ENSG00000164399 ENSG00000137801 ENSG00000043355 ENSG00000180447 ENSG00000111537 ENSG00000112210 ENSG00000113558 ENSG00000164093 ENSG00000185591 ENSG00000273529 ENSG00000133961 ENSG00000114315 ENSG00000128602 ENSG00000146648 PMC9136572__F3 Bile acid coordinates microbiota homeostasis and systemic immunometabolism in cardiometabolic diseases ENSG00000162711 ENSG00000135218 ENSG00000136869 ENSG00000267534 ENSG00000254550 PMC8137523__F1 Inhibition of the mevalonate pathway by statins affects several outputs and lipid-regulating transcription factors ENSG00000131473 ENSG00000110921 ENSG00000112972 ENSG00000153989 ENSG00000197429 ENSG00000113161 ENSG00000186480 ENSG00000167508 ENSG00000160752 ENSG00000067064 ENSG00000130164 ENSG00000152904 ENSG00000163914 ENSG00000120942 ENSG00000148459 PMC8137523__F2 Oncogenic signaling pathways play a dual role in generating tumor hallmarks that increase demand for mevalonate pathway intermediates while concurrently upregulating mevalonate pathway meet the demand ENSG00000131473 ENSG00000163914 ENSG00000168036 PMC7550403__F1 Pathways of complement activation with complement regulators and inhibitors highlighted ENSG00000196352 ENSG00000117335 ENSG00000244731 ENSG00000236625 PMC4831273__F9 How the source and context of activated GAs and cAMP may determine whether they enhance or inhibit TCR-stimulated IL-2 transcription ENSG00000213658 ENSG00000124181 PMC4180336__F5 Bile acid feedback inhibition of bile acid synthesis ENSG00000160867 ENSG00000180432 PMC9136572__F2 Bile acid coordinates microbiota homeostasis and systemic immunometabolism in cardiometabolic diseases ENSG00000171105 ENSG00000130164 ENSG00000042832 ENSG00000167910 ENSG00000015520 ENSG00000180432 ENSG00000100979 ENSG00000132855 ENSG00000115271 ENSG00000135929 ENSG00000026103 PMC9277228__F2 Necroptosis and Neuroinflammation in Retinal Degeneration ENSG00000183735 ENSG00000137275 ENSG00000102871 ENSG00000172936 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC1855990__F2 Identification of Key Processes Underlying Cancer Phenotypes Using Biologic Pathway Analysis ENSG00000157404 ENSG00000005339 PMC8137523__F5 Prenyltransferase biology is key to identifying targets of statin anti-cancer effects ENSG00000163914 ENSG00000113558 ENSG00000285193 ENSG00000188647 ENSG00000168522 PMC8137523__F6 Rational combinations enhancing the effects of statins at the mitochondria ENSG00000167468 ENSG00000171791 ENSG00000102967 PMC8137523__F4 Tumor suppressors act as a checkpoint for mevalonate pathway flux by suppressing SREBP activity ENSG00000134086 ENSG00000186480 ENSG00000140464 PMC5343835__F3 Proposed interaction of AQP1 with Wnt/ Beta-catenin signalling and cadherin-catenin complex ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC2817557__F2 Molecular Modulation of Intestinal Epithelial Barrier: Contribution of Microbiota ENSG00000167207 ENSG00000136869 ENSG00000150455 PMC5872357__F1 Epac signalosome in cardiac hypertrophy and ischemia ENSG00000291972 ENSG00000198626 PMC5584153__F4 Inhibition of PI3K/Akt/mTOR signaling in PI3KR2-overexpressing colon cancer stem cells reduces tumor growth due to apoptosis ENSG00000002330 ENSG00000138798 ENSG00000169429 PMC4171211__F11 Proposed model of tetrandrine-induced apoptosis in prostate cancer ENSG00000168040 ENSG00000026103 PMC9166517__F8 Network Pharmacology-Based Strategy Combined with Molecular Docking and in vitro Validation Study to Explore the Underlying Mechanism of Huo Luo Xiao Ling Dan in Treating Atherosclerosis ENSG00000087095 ENSG00000170458 ENSG00000102871 ENSG00000130522 ENSG00000138798 ENSG00000130159 ENSG00000127191 ENSG00000026103 PMC8103031__F2 CBP-JMF: An Improved Joint Matrix Tri-Factorization Method for Characterizing Complex Biological Processes of Diseases ENSG00000115163 ENSG00000065361 ENSG00000173156 ENSG00000134215 ENSG00000160182 ENSG00000129226 ENSG00000129514 ENSG00000103024 ENSG00000073111 ENSG00000163882 ENSG00000150991 ENSG00000169750 ENSG00000132646 ENSG00000177606 ENSG00000074410 ENSG00000160293 ENSG00000175792 PMC8103031__F3 CBP-JMF: An Improved Joint Matrix Tri-Factorization Method for Characterizing Complex Biological Processes of Diseases ENSG00000162889 ENSG00000065361 ENSG00000169750 ENSG00000101224 ENSG00000160293 PMC10860311__F1 Ovarian clear cell cancer carcinogenesis ENSG00000117713 ENSG00000121879 PMC7693401__F2 Toll-like 4 receptor signaling in MCs ENSG00000170458 ENSG00000010810 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC7693401__F3 Control of TLR4-mediated signaling in MCs ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC5094751__F12 Comparative Gene Expression Profiling of Primary and Metastatic Renal Cell Carcinoma Stem Cell-Like Cancer Cells ENSG00000173821 ENSG00000100234 ENSG00000165188 ENSG00000081181 ENSG00000122694 ENSG00000277399 ENSG00000183878 ENSG00000169862 ENSG00000121904 ENSG00000163739 ENSG00000135451 ENSG00000123179 ENSG00000113161 ENSG00000054654 ENSG00000249992 ENSG00000254999 ENSG00000120885 ENSG00000171791 ENSG00000104332 ENSG00000105894 ENSG00000076864 ENSG00000288411 ENSG00000196923 ENSG00000170430 ENSG00000140543 ENSG00000001626 ENSG00000123983 ENSG00000164220 ENSG00000100285 ENSG00000137673 ENSG00000137501 ENSG00000113070 ENSG00000086991 ENSG00000090776 ENSG00000164120 ENSG00000140416 ENSG00000185652 ENSG00000122254 ENSG00000133110 ENSG00000124882 ENSG00000100985 ENSG00000151617 ENSG00000140839 ENSG00000163638 ENSG00000204175 ENSG00000006016 ENSG00000150630 PMC9372913__F8 WNT4 overexpression and secretion in thymic epithelial tumors drive an autocrine loop in tumor cells in vitro ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000196628 ENSG00000106829 ENSG00000071564 ENSG00000065717 ENSG00000163914 ENSG00000177606 ENSG00000075275 ENSG00000026508 PMC7693401__F4 Molecular events involved in the response of MCs to mediators produced by cell damage and stress ENSG00000137033 ENSG00000010810 ENSG00000189403 ENSG00000172936 ENSG00000136869 PMC3864445__F2 Fermentative hydrogen production from glucose by E PMC6771012__F3 Molecules and cellular pathways that contribute to thyroid cancer development ENSG00000157764 ENSG00000134982 ENSG00000198793 ENSG00000164362 ENSG00000168036 PMC2658537__F1 Sample signalling scheme showing pathways known to be active in melanoma ENSG00000002330 ENSG00000157764 ENSG00000198793 PMC3233530__F2 Insertional mutagenesis identifies multiple networks of co-operating genes driving intestinal tumorigenesis ENSG00000107779 ENSG00000121989 ENSG00000170365 ENSG00000005339 ENSG00000157764 ENSG00000221914 ENSG00000156574 ENSG00000135503 ENSG00000139687 ENSG00000127616 PMC4531430__F6 miRNA–gene–pathway regulatory networks ENSG00000107562 ENSG00000112964 ENSG00000058085 ENSG00000134215 ENSG00000113161 ENSG00000164171 ENSG00000114279 PMC4909106__F4 Innate sensing of Toxoplasma gondii and Plasmodium sp ENSG00000239732 ENSG00000088888 ENSG00000140968 ENSG00000172936 ENSG00000276561 PMC10572711__F2 Major and other possible molecular pathways associated with NLRs in IBD ENSG00000278718 ENSG00000162711 ENSG00000167207 ENSG00000187796 ENSG00000174885 ENSG00000091592 ENSG00000274571 ENSG00000091106 ENSG00000088888 ENSG00000160703 ENSG00000142405 ENSG00000136869 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC6326574__F1 Immunological mechanisms responsible for radiation-induced abscopal effect ENSG00000164430 ENSG00000134982 ENSG00000157601 PMC8517268__F7 Dynamic m6A mRNA Methylation Reveals the Role of METTL3/14-m6A-MNK2-ERK Signaling Axis in Skeletal Muscle Differentiation and Regeneration ENSG00000145388 ENSG00000149658 ENSG00000165819 PMC6914705__F10 Schematic representation of how SteA suppresses the nuclear factor kappa B (NFKB) pathway ENSG00000113558 ENSG00000111530 ENSG00000285246 PMC3478886__F1 Prognostic Value of Cell-Cycle Regulation Biomarkers in Bladder Cancer ENSG00000135446 ENSG00000123374 ENSG00000146648 PMC3109595__F5 Gene regulatory network model for specification of the skeletogenic mesoderm lineage ENSG00000157554 ENSG00000053254 ENSG00000285493 ENSG00000170802 PMC8250126__F1 Janus kinase signaling as risk factor and therapeutic target for severe SARS‐CoV‐2 infection ENSG00000130234 PMC6152668__F3 DET- and IDET-induced apoptosis in different cancer cell lines ENSG00000198793 ENSG00000168040 ENSG00000026103 PMC8861201__F1 Metabolic Engineering for Valorization of Agri- and Aqua-Culture Sidestreams for Production of Nitrogenous Compounds by Corynebacterium glutamicum ENSG00000122966 ENSG00000183691 ENSG00000172005 PMC7947867__F4 Model showing plasma membrane NKCC1 and mitochondrial respiration: a link through leucine? Aerobic respiration utilizes the KREBS cycle and the electron transport chain ENSG00000169047 ENSG00000100219 PMC8761794__F2 CGAS/STING Pathway: A Novel Target for Cancer Therapy ENSG00000169248 ENSG00000169245 ENSG00000164430 ENSG00000173638 ENSG00000007171 PMC8761794__F3 CGAS/STING Pathway: A Novel Target for Cancer Therapy ENSG00000183735 ENSG00000164430 PMC8761794__F1 CGAS/STING Pathway: A Novel Target for Cancer Therapy ENSG00000169245 ENSG00000183735 ENSG00000089127 ENSG00000115415 ENSG00000142166 PMC10526343__F1 Comprehensive Review on Neuroimmunology: Insights from Multiple Sclerosis to Future Therapeutic Developments ENSG00000134982 ENSG00000162692 PMC4748726__F4 Network of osteogenic specific proteins regulated by BMP2 signaling ENSG00000029559 ENSG00000242252 ENSG00000118785 ENSG00000162551 ENSG00000113140 ENSG00000108821 PMC9563116__F2 Biochemical Pathways of Cellular Mechanosensing/Mechanotransduction and Their Role in Neurodegenerative Diseases Pathogenesis ENSG00000144857 ENSG00000163914 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC9628242__F6 Tetrahedral framework nucleic acids promote diabetic wound healing via the Wnt signalling pathway ENSG00000138795 ENSG00000168036 ENSG00000112715 PMC8835964__F8 Mitochondrial PHB2/OMA1/DELE1 Pathway Cooperates with Endoplasmic Reticulum Stress to Facilitate the Response to Chemotherapeutics in Ovarian Cancer ENSG00000215021 ENSG00000105327 ENSG00000128272 ENSG00000162600 ENSG00000153094 ENSG00000169136 ENSG00000081791 ENSG00000165283 ENSG00000086232 PMC8424636__F7 Nicorandil inhibits TLR4/MyD88/NFKB/NLRP3 signaling pathway to reduce pyroptosis in rats with myocardial infarction ENSG00000278718 ENSG00000162711 ENSG00000172936 ENSG00000136869 PMC10565453__F2 Organelle-level mechanisms of mitochondrial quality control ENSG00000168958 ENSG00000096717 ENSG00000164087 ENSG00000106459 ENSG00000214253 PMC7827341__F2 IL-1A signaling pathway ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC8143883__F6 MicroRNA-342 Promotes the Malignant-Like Phenotype of Endometrial Stromal Cells via Regulation of Annexin A2 ENSG00000182718 ENSG00000198793 PMC10565453__F3 Altered mitochondrial quality control in renal tubule cells under high glucose conditions ENSG00000198793 ENSG00000158828 ENSG00000265972 ENSG00000179364 ENSG00000142082 ENSG00000168610 ENSG00000121966 ENSG00000106459 ENSG00000100253 ENSG00000215021 ENSG00000247077 ENSG00000171109 ENSG00000214253 PMC7713123__F1 Pathway engineering in yeast for synthesizing the complex polyketide bikaverin ENSG00000291931 ENSG00000105205 PMC12134904__F5 IL-2 Action ENSG00000198793 ENSG00000049768 ENSG00000105639 PMC10298860__F11 Albino phenotype of ‘HJY’ might be modulated by a plastid retrograde signaling pathway ENSG00000127948 ENSG00000127125 PMC8471942__F1 Genetic Aberrations of DNA Repair Pathways in Prostate Cancer: Translation to the Clinic ENSG00000012061 ENSG00000149311 ENSG00000175054 ENSG00000079246 ENSG00000051180 ENSG00000253729 PMC4127075__F1 Regulation of EMT by KLF4 in Gastrointestinal Cancer ENSG00000165556 ENSG00000168283 ENSG00000134057 ENSG00000142089 ENSG00000136826 ENSG00000170477 ENSG00000241794 PMC4127075__F2 Regulation of EMT by KLF4 in Gastrointestinal Cancer ENSG00000148400 ENSG00000138798 ENSG00000170558 ENSG00000198793 ENSG00000168036 ENSG00000168610 ENSG00000146648 ENSG00000136826 PMC9273993__F3 Multifaceted Roles of Chemokine C-X-C Motif Ligand 7 in Inflammatory Diseases and Cancer ENSG00000163464 ENSG00000198793 PMC9877271__F1 Unfolded protein response and ER-associated degradation under freezing, anoxia, and dehydration stresses in the freeze-tolerant wood frogs ENSG00000128272 ENSG00000162772 PMC8515174__F2 Complement inhibition for the treatment of COVID-19 triggered thrombotic microangiopathy with cardiac failure: a case report ENSG00000281244 ENSG00000261857 PMC6310057__F1 Potential targets of glucose metabolism for anticancer therapy PMC6769561__F2 Schematic summarizing the molecular mechanisms contributing to cancer progression ENSG00000168610 ENSG00000146648 PMC5751948__F1 Activation of NFKB (nuclear factorKB) by canonical and atypical pathways ENSG00000104856 ENSG00000226275 ENSG00000173599 ENSG00000173039 PMC2395050__F1 PG-recycling pathway of the wild type (A) and trapping of anhMurNAc-tripeptide in an ampD mutant (B) ENSG00000112977 ENSG00000117400 PMC10935119__F9 Enzastaurin, midostaurin, and lestaurtinib ENSG00000122025 ENSG00000198793 PMC5447271__F1 Illustration of Wnt signaling cascades ENSG00000087095 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9380940__F3 Causal network predicted for STAT3 regulator showing its relationship with obesity and inflammatory response, obtained using Ingenuity Pathway Analysis (IPA) ENSG00000115138 ENSG00000168610 PMC7821690__F1 Crosstalk Signaling and miRNA Deregulation in Obesity Related Breast Cancer ENSG00000002330 ENSG00000291971 ENSG00000150907 ENSG00000168610 PMC4329227__F2 Pentose phosphate pathway and cancer ENSG00000149311 ENSG00000197713 ENSG00000291971 ENSG00000198793 ENSG00000136997 ENSG00000078237 PMC12076877__F3 Aryl hydrocarbon receptor: a new frontier in male reproductive system ENSG00000106546 PMC4884395__F1 Kynurenine pathway of tryptophan metabolism ENSG00000125538 ENSG00000131095 ENSG00000188676 PMC4344557__F2 Proposed mechanism of action of yerba maté on the modulation of the PI3K-AKT signaling pathway ENSG00000169047 ENSG00000168036 PMC4773443__F5 Metabolic intermediates regulate Yersinia virulence ENSG00000261701 ENSG00000173039 ENSG00000132693 PMC9268458__F1 Gene-Environment Interactions in Vitamin D Status and Sun Exposure: A Systematic Review with Recommendations for Future Research ENSG00000172893 ENSG00000145321 ENSG00000186104 PMC3629228__F2 De-Regulated MicroRNAs in Pediatric Cancer Stem Cells Target Pathways Involved in Cell Proliferation, Cell Cycle and Development ENSG00000149311 ENSG00000175054 ENSG00000262634 ENSG00000111537 ENSG00000136997 ENSG00000156574 ENSG00000134363 ENSG00000123374 ENSG00000112378 ENSG00000164305 ENSG00000137801 PMC11201201__F2 VEGFR activation by the VEGF family of growth factors and resulting downstream signaling pathways to angiogenesis and lymphangiogenesis ENSG00000198793 ENSG00000112715 ENSG00000150630 PMC4149734__F5 Turnover of proteins in metabolic pathways in barley leaves ENSG00000261701 ENSG00000184207 ENSG00000127948 PMC8001935__F3 PPI-specific gene-regulatory networks of top 5 KDs in IGF-I and IR (eQTL mapping) ENSG00000196296 ENSG00000171105 ENSG00000170027 ENSG00000170558 ENSG00000169047 ENSG00000169032 ENSG00000182621 ENSG00000143375 ENSG00000174996 ENSG00000182511 ENSG00000078747 ENSG00000067606 ENSG00000186716 ENSG00000149273 ENSG00000103769 ENSG00000178568 PMC7961896__F2 Unfolded protein response (UPR) pathways in skeletal muscle ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC3024731__F2 Examples of the signaling role of Cdc42 in selective tissue cell types ENSG00000070831 ENSG00000105656 PMC7961896__F1 Molecular mechanisms regulating skeletal muscle mass ENSG00000137834 ENSG00000178573 ENSG00000198793 ENSG00000135414 ENSG00000164327 ENSG00000127191 ENSG00000140443 PMC9474891__F2 Role and regulatory mechanism of m6A methylation in the nervous system ENSG00000115875 ENSG00000122566 ENSG00000145388 ENSG00000115457 ENSG00000198793 ENSG00000170430 ENSG00000146457 ENSG00000092199 ENSG00000165819 ENSG00000159399 PMC9335447__F6A MicroRNA global profiling in cystic fibrosis cell lines reveals dysregulated pathways related with inflammation, cancer, growth, glucose and lipid metabolism, and fertility: an exploratory study ENSG00000262634 ENSG00000157404 ENSG00000100473 ENSG00000111537 ENSG00000095739 ENSG00000111837 ENSG00000128052 ENSG00000108443 ENSG00000162924 ENSG00000112715 ENSG00000160691 PMC7372882__F7 PI3K-AKT signaling pathway plays a central role in anti-TAO system of SP ENSG00000081041 ENSG00000171105 ENSG00000002330 ENSG00000138798 ENSG00000111837 ENSG00000169047 ENSG00000171791 ENSG00000112715 ENSG00000073756 ENSG00000026103 PMC5264313__F4 Microarray analysis reveals alterations in the expression of major pathways of cellular metabolism in response to changes in collagen extracellular matrix density.A ENSG00000284320 ENSG00000092621 ENSG00000146733 PMC8189684__F3 MEScan: a powerful statistical framework for genome-scale mutual exclusivity analysis of cancer mutations ENSG00000167258 ENSG00000012048 ENSG00000116044 ENSG00000181163 ENSG00000198793 ENSG00000121879 ENSG00000146648 ENSG00000196712 ENSG00000079999 PMC7257216__F8 Schematic diagram illustrating the mechanism by which asiaticoside inhibited MMT and ROS generation ENSG00000105329 PMC4786634__F1 Both signal 1 and signal 2 are required for NLRP3 inflammasome activation ENSG00000162711 ENSG00000088888 ENSG00000116688 ENSG00000125538 ENSG00000172936 ENSG00000265972 PMC5706502__F5 NcRNAs involved in mTOR signalling pathway ENSG00000169047 ENSG00000155792 ENSG00000109270 ENSG00000140443 PMC4352384__F5 Polymicrobial synergy and dysbiosis in inflammatory disease ENSG00000174125 ENSG00000198742 ENSG00000172005 ENSG00000172936 PMC4352384__F6 Polymicrobial synergy and dysbiosis in inflammatory disease ENSG00000174125 ENSG00000162711 ENSG00000125538 ENSG00000136869 ENSG00000121966 PMC8444018__F4 Temporary Regulatory Deviations and the Coronavirus Disease 2019 (COVID-19) PCR Labeling Update Study Indicate What Laboratory-Developed Test Regulation by the US Food and Drug Administration (FDA) Could Look Like ENSG00000134982 ENSG00000128928 PMC10840489__F3 Endosomal and cytoplasmic viral RNA sensing by RLRs and TLRs ENSG00000088888 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC11758981__F1 Gut microbial regulation of lipids reflects the influence of gut microbiota on hyperlipidemia in various treatment methods ENSG00000130173 ENSG00000132855 PMC4367433__F2 Pathway for protein modification by UFM1 ENSG00000014123 ENSG00000143222 ENSG00000120686 ENSG00000081307 PMC10604364__F3 Illustration depicting the formation and fate of hybrid cells ENSG00000178860 ENSG00000168036 ENSG00000136869 PMC4367433__F4 Pathway for estrogen-induced ASC1 ufmylation for ERA transactivation ENSG00000120686 ENSG00000167182 PMC6027295__F1 Main signaling pathways of adiponectin in healthy liver ENSG00000159346 ENSG00000285070 PMC4440546__F5 Context-dependent control of alternative splicing by RNA-binding proteins ENSG00000146648 PMC1895802__F1 TGFB signaling pathway and mechanisms of inhibition during leukemogenesis ENSG00000137834 PMC7273480__F9 Metabolic pathway analysis ENSG00000169291 ENSG00000090402 ENSG00000080823 PMC7457738__F8 Proposed schematic representation for GAST in GC development and progression ENSG00000291971 ENSG00000168610 PMC3924831__F2 Apoptosis signaling under ER stress conditions ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC6133308__F1 KEAP1-NRF2 pathway is altered in human lung cancers.Schematic of KEAP1-NRF2 pathway under homeostatic conditions (left), oxidative conditions (center) or synergistic conditions, for example in a cancer cell (right) ENSG00000178573 ENSG00000079999 PMC4252505__F3 Hras-Braf MAP-Kinase pathway visualized using GenMAPP software ENSG00000157764 ENSG00000095015 ENSG00000149782 ENSG00000065559 ENSG00000169032 ENSG00000139625 ENSG00000076864 ENSG00000169967 ENSG00000197971 ENSG00000213445 ENSG00000177606 ENSG00000280477 ENSG00000126458 PMC5719347__F7 Signalling pathways associated with PRDXs and hypothetical illustration of PRDXs in mouse spermatozoa ENSG00000173221 ENSG00000271303 ENSG00000146648 ENSG00000026103 PMC8851036__F2 Advances of Adjunctive Hyperbaric Oxygen Therapy in Infective Endocarditis ENSG00000105664 ENSG00000136869 ENSG00000162692 ENSG00000005381 PMC10384495__F2 Molecular and Genetic Interactions between Obesity and Breast Cancer Risk ENSG00000198793 ENSG00000159346 ENSG00000285070 ENSG00000168610 PMC6667461__F1 Overview of direct and indirect pro-allergenic immune responses to anti-ulcer drugs (AUD) ENSG00000111816 ENSG00000106546 PMC5613156__F3 NOD-like receptors control various forms of PCD in mammals and filamentous fungi ENSG00000047410 ENSG00000162711 ENSG00000174145 ENSG00000120868 PMC2803786__F2 Network analysis of the top 250 predictor genes ENSG00000213928 ENSG00000117228 ENSG00000143878 ENSG00000185479 ENSG00000120875 ENSG00000159461 ENSG00000106299 ENSG00000170606 ENSG00000215305 ENSG00000121966 ENSG00000106546 ENSG00000102241 ENSG00000214114 ENSG00000288411 ENSG00000149136 ENSG00000153879 ENSG00000007402 ENSG00000184900 PMC2198843__F1 Adhesion regulation of nucleocytoplasmic trafficking of signaling molecules ENSG00000147044 ENSG00000138795 ENSG00000134982 PMC8575484__F3 Identification of Candidate Genes Related to Synovial Macrophages in Rheumatoid Arthritis by Bioinformatics Analysis ENSG00000002330 ENSG00000172005 PMC9467755__F2 Natural Compounds for SIRT1-Mediated Oxidative Stress and Neuroinflammation in Stroke: A Potential Therapeutic Target in the Future ENSG00000162711 ENSG00000189403 PMC10313304__F9 Exploring the active ingredients and mechanism of Shenzhi Tongxin capsule against microvascular angina based on network pharmacology and molecular docking ENSG00000087095 ENSG00000170458 ENSG00000102871 ENSG00000117400 ENSG00000130522 ENSG00000127191 ENSG00000111816 ENSG00000081189 ENSG00000026103 PMC3784473__F9 The Suf Iron-Sulfur Cluster Synthesis Pathway Is Required for Apicoplast Maintenance in Malaria Parasites ENSG00000107798 ENSG00000197429 PMC7122562__F2 Viral infection suppresses autophagy ENSG00000177169 ENSG00000169047 ENSG00000144848 PMC7122562__F3 Viruses manipulate autophagy to promote their replication ENSG00000198382 ENSG00000134109 ENSG00000088888 ENSG00000107862 ENSG00000143761 ENSG00000144848 ENSG00000237693 ENSG00000099940 ENSG00000145782 ENSG00000057663 ENSG00000136874 PMC4562884__F1 Spatial and temporal aspects of Wnt signaling and planar cell polarity during vertebrate embryonic development ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000163914 PMC8185109__F3 Mitochondrial ER contact sites in neurodegeneration ENSG00000142192 ENSG00000116688 ENSG00000156026 ENSG00000173599 ENSG00000158828 ENSG00000057663 PMC10530616__F15 Schematic illustration for the effects of Actinidia deliciosa (kiwi) extract on pathways related to T2DM ENSG00000002330 ENSG00000096717 ENSG00000168610 ENSG00000079999 PMC7891678__F1 TGFB as a gatekeeper of BMP action in the developing growth plate ENSG00000170365 ENSG00000137834 ENSG00000139567 PMC8727908__F2 Hexosamine Biosynthetic Pathway Links Innate Inflammation With Epithelial-Mesenchymal Plasticity in Airway Remodeling ENSG00000141867 ENSG00000124216 ENSG00000173039 ENSG00000100985 PMC8692109__F8 Human Alpha-defensin 6 (HD6) suppresses CRC proliferation and metastasis through abolished EGF/EGFR signaling pathway ENSG00000138798 ENSG00000023892 ENSG00000145386 ENSG00000146648 PMC8727908__F5 Hexosamine Biosynthetic Pathway Links Innate Inflammation With Epithelial-Mesenchymal Plasticity in Airway Remodeling ENSG00000136807 ENSG00000141867 ENSG00000101751 ENSG00000173039 ENSG00000100985 ENSG00000166169 ENSG00000127616 PMC8727908__F6 Hexosamine Biosynthetic Pathway Links Innate Inflammation With Epithelial-Mesenchymal Plasticity in Airway Remodeling ENSG00000117713 ENSG00000141867 ENSG00000173039 ENSG00000136146 ENSG00000100985 PMC3812255__F2 Serotonin Gene Variants are Unlikely to Play a Significant Role in the Pathogenesis of the Sudden Infant Death Syndrome ENSG00000139287 ENSG00000197386 ENSG00000163497 PMC11748645__F8 PD-L1 monoclonal antibody improves left ventricular function by modulating the CD47/SHP2/SIRPA/SYK/FcGR signaling pathway in tumor-associated macrophages, thereby inhibiting cGAMP expression ENSG00000162711 ENSG00000164430 PMC8727908__F8 Hexosamine Biosynthetic Pathway Links Innate Inflammation With Epithelial-Mesenchymal Plasticity in Airway Remodeling ENSG00000086991 ENSG00000100985 PMC5529431__F5 Representation of the putative signaling pathways involved in B-cell clonogenicity induced by interaction of S75X/p17R76G with p17R(s) ENSG00000132906 ENSG00000149269 ENSG00000075891 ENSG00000123374 ENSG00000183765 PMC11748645__F5 PD-L1 monoclonal antibody alleviated MI injury of left ventricular function via modulating CD47/SHP2/SIRPA/SYK/FcGR signalings in tumor associated macrophages ENSG00000198053 ENSG00000136997 ENSG00000168610 PMC1483167__F1 Liver X receptor opens a new gateway to StAR and to steroid hormones ENSG00000130164 ENSG00000026103 PMC3815023__F2 Functional Networking of Human Divergently Paired Genes (DPGs) ENSG00000021776 ENSG00000178078 ENSG00000086589 ENSG00000160799 ENSG00000179950 ENSG00000117399 ENSG00000035720 ENSG00000276876 ENSG00000145604 ENSG00000162385 ENSG00000085872 ENSG00000094804 ENSG00000132646 ENSG00000123374 ENSG00000240682 PMC12250376__F9 Overexpression of (P)RR in SHR and Renin-Induced HepG2 Cells Leads to Spontaneous Hypertension Combined with Metabolic Dysfunction-Associated Fatty Liver Disease ENSG00000135218 ENSG00000042832 ENSG00000169710 PMC11955602__F0 Diagram illustrates how herbal formulations and extracts derived from TCM exert potential effects on AD through modulation of the PI3K/AKT signaling pathway ENSG00000002330 PMC9600997__F8 TRAF3/p38-JNK Signalling Crosstalk with Intracellular-TRAIL/Caspase-10-Induced Apoptosis Accelerates ROS-Driven Cancer Cell-Specific Death by CD40 ENSG00000056558 ENSG00000131323 ENSG00000175104 PMC6826992__F9 Models of EGFR-ligand dependent pathway and EGFR-ligand independent pathway in EIS cells ENSG00000065361 ENSG00000291971 ENSG00000146648 PMC2891338__F1 Endotoxin binding: Schematic overview of the LPS, LBP, CD14 and TLR-4 signal transduction pathway ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC7042390__F9 Wnt signaling pathway ENSG00000162552 ENSG00000087095 ENSG00000154764 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000188064 ENSG00000168036 ENSG00000125084 PMC6617733__F1 Distinct molecular and morphologic features of apoptotic, necroptotic, and necrotic cell death ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000112186 ENSG00000168404 ENSG00000127191 PMC3410255__F1 Regulation of PTEN/PI3K/AKT pathway by microRNAs PMC4879160__F4 Sclerostin actions ENSG00000152266 ENSG00000281324 ENSG00000162337 ENSG00000134569 PMC12000830__F2 Regulatory role of MEG3 in cancer progression and suppression ENSG00000150782 ENSG00000128045 ENSG00000179295 PMC9004513__F1 MTORC1 Activity by Amino Acids and Growth Factors ENSG00000177058 ENSG00000198793 ENSG00000145979 ENSG00000141458 ENSG00000167965 ENSG00000239282 ENSG00000187778 PMC12000830__F3 MEG3 lncRNA: a key regulator of tumor suppression across multiple cancer pathways ENSG00000087245 ENSG00000198793 ENSG00000100985 ENSG00000168610 PMC10151763__F2 Klotho’s impact on diabetic nephropathy and its emerging connection to diabetic retinopathy ENSG00000188064 ENSG00000133116 ENSG00000168036 PMC6458732__F6 A leucine-rich diet modulates the mTOR cell signalling pathway in the gastrocnemius muscle under different Walker-256 tumour growth conditions ENSG00000169047 ENSG00000198793 ENSG00000168610 PMC10151763__F1 Klotho’s impact on diabetic nephropathy and its emerging connection to diabetic retinopathy ENSG00000118972 ENSG00000168036 ENSG00000136869 ENSG00000140443 PMC5543436__F1 a The subcellular localization of the three isocitrate dehydrogenase isoforms and their roles in normal cellular metabolism ENSG00000026103 PMC5418193__F1 Insulin/insulin growth factor signaling pathway and its activation by reactive oxygen species (ROS) PMC8595768__F3 Oxidative stress-induced damage of IDE and BVR-A is associated with development of brain insulin resistance ENSG00000198793 ENSG00000119912 PMC7407108__F1 Hippo pathway ENSG00000186575 ENSG00000144560 ENSG00000163914 ENSG00000166025 ENSG00000139926 ENSG00000131023 PMC8264455__F1 Antioxidant Therapy and Antioxidant-Related Bionanomaterials in Diabetic Wound Healing ENSG00000178573 ENSG00000079999 PMC8595768__F1 Insulin signaling ENSG00000169047 ENSG00000198793 PMC5382875__F1 Cytosolic co-delivery of miRNA-34a and docetaxel with core-shell nanocarriers via caveolae-mediated pathway for the treatment of metastatic breast cancer ENSG00000148400 ENSG00000026508 ENSG00000105810 ENSG00000096717 PMC11668677__F6 Summarizing figure for NA protective effect on lung tissues against the toxic effects of radiation ENSG00000105329 ENSG00000118520 ENSG00000007171 PMC8197487__F7 Developments for Collagen Hydrolysate in Biological, Biochemical, and Biomedical Domains: A Comprehensive Review ENSG00000169291 ENSG00000002330 ENSG00000167207 ENSG00000187796 ENSG00000150907 ENSG00000177606 ENSG00000175104 ENSG00000106100 ENSG00000111816 PMC8449777__F7 Schematic showing the mechanisms underlying miR-2337 induction of TGFB1 production in GCs ENSG00000123908 PMC8198882__F1 Inflammasome NLRP3 Potentially Links Obesity-Associated Low-Grade Systemic Inflammation and Insulin Resistance with Alzheimer’s Disease ENSG00000150907 ENSG00000198793 ENSG00000164327 PMC4054275__F11 Proposed regulatory mechanism of protein tyrosine phosphatases in C ENSG00000157554 ENSG00000123268 PMC6930621__F10 Hepatic metabolic pathways of Met ENSG00000205221 PMC8132252__F2 Biological and Clinical Factors contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19 ENSG00000110799 ENSG00000173599 ENSG00000151388 PMC9513044__F2 Antitumor effects of fecal microbiota transplantation: Implications for microbiome modulation in cancer treatment ENSG00000134982 ENSG00000168036 ENSG00000168610 PMC7249743__F8 Potentially HCC-related KEGG pathways ENSG00000184990 ENSG00000108055 ENSG00000198793 ENSG00000205250 ENSG00000277273 ENSG00000023697 ENSG00000164305 ENSG00000093009 ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000132646 ENSG00000136997 ENSG00000115942 ENSG00000042286 ENSG00000135336 ENSG00000123374 ENSG00000112378 ENSG00000026103 PMC9513044__F1 Antitumor effects of fecal microbiota transplantation: Implications for microbiome modulation in cancer treatment ENSG00000118520 ENSG00000168610 ENSG00000007171 PMC9697637__F2 Marine Natural Products from the Russian Pacific as Sources of Drugs for Neurodegenerative Diseases ENSG00000142192 PMC6349152__F1 The role of SUMO in kidney fibrosis ENSG00000134086 PMC7378533__F2 Type I IFN due to the activation of IFN receptors ENSG00000105397 ENSG00000115415 ENSG00000168610 PMC3773303__F3 Clathrin-dependent and -independent endocytosis of STx ENSG00000070831 ENSG00000163914 PMC5845882__F8 gga-miR-155 and the suppression of IBDV replication ENSG00000183735 ENSG00000276561 ENSG00000164342 PMC7759095__F4 SARS-CoV-2 infection and signaling pathways as potential targets for treatment ENSG00000130234 ENSG00000184012 PMC9057928__F3 Emerging roles of retromer and sorting nexins in the life cycle of viruses ENSG00000205302 ENSG00000143376 ENSG00000069329 PMC1904449__F3 In silico modeling derived from Pathway Assist software analysis of differential gene expression in JRA neutrophils compared with healthy control subjects ENSG00000125740 ENSG00000182511 ENSG00000006451 ENSG00000148926 ENSG00000158825 ENSG00000277263 ENSG00000112149 ENSG00000115523 PMC7896749__F3 LncRNA‐mediated posttranslational modification of other proteins involved in metabolic pathways ENSG00000096717 PMC9576507__F3 Pyroptotic cell death in SARS-CoV-2 infection: revealing its roles during the immunopathogenesis of COVID-19 ENSG00000278718 ENSG00000162711 ENSG00000130234 ENSG00000163568 ENSG00000091592 ENSG00000091106 ENSG00000127948 PMC8893235__F2 Promising Therapeutic Candidate for Myocardial Ischemia/Reperfusion Injury: What Are the Possible Mechanisms and Roles of Phytochemicals? ENSG00000012048 ENSG00000177169 ENSG00000083290 PMC5751344__F3 Involvement of galectins during carcinogenesis ENSG00000134982 ENSG00000168036 PMC9437339__F9 Apolipoprotein A-I mimetic peptides (ApoAI MP) improve oxidative stress and inflammatory responses in Parkinson’s disease mice ENSG00000100591 ENSG00000103266 ENSG00000115008 ENSG00000105401 ENSG00000113070 ENSG00000243509 ENSG00000168610 ENSG00000004478 ENSG00000173992 ENSG00000102245 ENSG00000125538 ENSG00000198670 ENSG00000158874 ENSG00000124181 ENSG00000096717 ENSG00000146648 ENSG00000023572 ENSG00000115594 PMC2684021__F1 The fungal cell wall and downstream cellular responses following engagement of Dectin-1 and TLRs on antigen presenting cells (APC) ENSG00000187796 ENSG00000134982 ENSG00000172936 PMC7038193__F3 Sp1 mediated tumorigenesis in ovarian cancer (OC) ENSG00000291971 ENSG00000185591 PMC8526690__F3 Mechanosensitive channel Piezo1/2 proteins in skeleton and other tissues ENSG00000178860 ENSG00000110711 ENSG00000128272 ENSG00000164761 ENSG00000167941 ENSG00000168036 ENSG00000073756 ENSG00000103335 PMC4383556__F9 Transcriptome Analysis and Its Application in Identifying Genes Associated with Fruiting Body Development in Basidiomycete Hypsizygus marmoreus ENSG00000105664 ENSG00000198793 ENSG00000168036 ENSG00000164327 ENSG00000080166 ENSG00000107165 ENSG00000122971 PMC9460496__F9 Transcriptional Memory in Taraxacum mongolicum in Response to Long-Term Different Grazing Intensities ENSG00000039537 ENSG00000182511 ENSG00000173599 PMC3703549__F8 Ang II activates the Notch1/Snail signaling, which is responsible for the pathogenesis of proteinuria in diabetic nephropathy ENSG00000148400 ENSG00000114315 PMC8911352__F2 Paediatric Behçet’s Disease: A Comprehensive Review with an Emphasis on Monogenic Mimics ENSG00000137275 ENSG00000102871 ENSG00000186716 ENSG00000173039 ENSG00000154124 PMC3697124__F3 Antibiotics doxycycline and minocycline inhibit inflammatory responses to the Lyme disease spirochete Borrelia burgdorferi ENSG00000104856 ENSG00000226275 ENSG00000138798 ENSG00000150455 PMC5809464__F9 Lipid metabolic pathway analysis of identified differential lipid species ENSG00000173599 ENSG00000154059 ENSG00000198874 PMC11410975__F0 ALKBH5 activated JAK2/STAT3 signaling pathway and mediated m6A demethylation on Stat3 mRNA, but not Jak2 mRNA, resulting in the phosphorylation and nuclear translocation of STAT3, which enhances the transcription of hypertrophic genes (e ENSG00000175206 ENSG00000091542 ENSG00000168610 ENSG00000120937 PMC2821954__F2 Portrayed here is a molecular pathway analysis of genes regulated in the mouse nucleus accumbens by a direct infusion of the HDAC inhibitor MS-275 after chronic social defeat stress ENSG00000084093 ENSG00000163235 ENSG00000163914 ENSG00000146648 PMC6826893__F5 Crosstalk between RAS-ERK pathway and FOXM1 ENSG00000145604 ENSG00000143507 PMC4713713__F3 Activation of autophagy and caspase-independent apoptosis pathway and proposed mechanism of action of magnetic nanoparticles functionalized with LL-37 on colon cancer cells ENSG00000057663 PMC3019079__F1 The homocysteine and folate metabolic pathway ENSG00000124275 ENSG00000035928 ENSG00000116984 PMC7494756__F1 Output and input pathways of the central circadian timing system in the mammalian brain that may be involved sundowning–related behavioral aggression and circadian dysfunction in Alzheimer’s disease and related dementias ENSG00000146469 PMC9499548__F4 Two Short Repeats in the 5′ Untranslated Region of Insulin-like Androgenic Gland Factor in Procambarus clarkii (PcIAG) That Regulate PcIAG Expression ENSG00000087095 ENSG00000107404 ENSG00000172680 ENSG00000130522 ENSG00000177606 PMC8967653__F1 Emerging Mechanisms of Growth and Patterning Regulation by Dachsous and Fat Protocadherins ENSG00000166341 ENSG00000142192 ENSG00000197905 ENSG00000007866 ENSG00000150457 ENSG00000074219 ENSG00000183580 PMC7683721__F7 Signaling cascade for the aberrant TRPV4 and calcium activation in endometrial cancer ENSG00000067900 ENSG00000089159 PMC11972515__F2 LncRNAs in acute myeloid leukemia ENSG00000253352 ENSG00000140443 PMC4595210__F4 Lactobacillus rhamnosus CNCMI-4317 Modulates Fiaf/Angptl4 in Intestinal Epithelial Cells and Circulating Level in Mice ENSG00000113369 ENSG00000122877 ENSG00000170425 ENSG00000114315 ENSG00000166123 PMC9319091__F11 VMP1 Regulated by chi-miR-124a Effects Goat Myoblast Proliferation, Autophagy, and Apoptosis through the PI3K/ULK1/mTOR Signaling Pathway ENSG00000198793 ENSG00000062716 PMC6721648__F2 Pathways of androgen action in the Sertoli cell ENSG00000291971 ENSG00000146648 PMC5105060__F9 Analysis of Zinc-Exporters Expression in Prostate Cancer ENSG00000152683 ENSG00000170385 ENSG00000171105 ENSG00000158014 ENSG00000204140 ENSG00000162595 ENSG00000119707 ENSG00000143376 ENSG00000162695 ENSG00000145740 ENSG00000105402 ENSG00000179913 ENSG00000277943 ENSG00000104154 ENSG00000066044 ENSG00000282604 ENSG00000164756 ENSG00000164400 PMC5094499__F1 Pleiotropic effects of hyperglycaemia‐induced miR‐126 underexpression and insulin resistance ENSG00000169047 ENSG00000166068 PMC6685059__F2 Translational challenges with systemic and local cell delivery ENSG00000178860 ENSG00000003436 ENSG00000118242 ENSG00000117335 ENSG00000010278 ENSG00000062485 PMC5418463__F1 Regulatory T (Treg) cells modulate CD8 T‐cell exhaustion, but the programmed cell death protein 1 (PD‐1) pathway determines viral control PMC6778255__F8 Schematic view of the role of AvB3-int in PD-L1 expression and antitumor immunity ENSG00000115415 PMC6266222__F3 Regulatory effects on immune-related pathways induced by a group of compounds from health-strengthening herbs ENSG00000159128 ENSG00000111537 ENSG00000010810 ENSG00000232326 ENSG00000143839 ENSG00000027697 ENSG00000127022 ENSG00000066136 ENSG00000273686 PMC6938582__F2 Action of metformin in endocrine tumors: metformin is a negatively charged molecule that enters the cell through organic cation transporters (OCTs) ENSG00000169047 ENSG00000198793 ENSG00000162772 ENSG00000168610 ENSG00000146648 PMC9596769__F3 Immunomodulatory potential of secretome from cartilage cells and mesenchymal stromal cells in an arthritic context: From predictive fiction toward reality ENSG00000145839 ENSG00000113520 ENSG00000164690 PMC6744391__F9 TAAR1 signaling pathway/apoptotic pathway components ENSG00000146399 PMC4084927__F10 Acetaminophen and NAPQI are Toxic to Auditory Cells via Oxidative and Endoplasmic Reticulum Stress-dependent Pathways ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC12060066__F4 Systematic Ocular Phenotyping of Knockout Mouse Lines Identifies Genes Associated With Age-Related Corneal Dystrophies ENSG00000002330 ENSG00000173786 ENSG00000145321 ENSG00000137672 PMC7198484__F4 Intracellular Staphylococcus aureus persisters upon antibiotic exposure ENSG00000117118 ENSG00000166816 ENSG00000115718 ENSG00000062485 PMC3280691__F1 Beta-catenin signaling: a novel mediator of fibrosis and potential therapeutic target ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000168646 PMC7723172__F3 Effects and mechanisms of corosolic acid-induced anti-inflammatory and anti-MS activities ENSG00000162711 ENSG00000169047 PMC8625880__F2 Genomic Instability and Cancer Risk Associated with Erroneous DNA Repair ENSG00000143799 ENSG00000012048 ENSG00000083093 ENSG00000105486 ENSG00000051180 ENSG00000177084 ENSG00000310560 ENSG00000139618 PMC8625880__F3 Genomic Instability and Cancer Risk Associated with Erroneous DNA Repair ENSG00000012061 ENSG00000292191 ENSG00000134574 ENSG00000132646 ENSG00000163945 ENSG00000167986 ENSG00000136936 PMC4700926__F1 The core autophagy pathway and its regulation by miRNAs ENSG00000152348 ENSG00000198382 ENSG00000144848 ENSG00000005893 ENSG00000171791 ENSG00000145782 ENSG00000095383 ENSG00000057663 PMC2758293__F2 An intracellular trafficking pathway in the seminiferous epithelium regulating spermatogenesis: A biochemical and molecular perspective ENSG00000130545 ENSG00000291971 ENSG00000170558 ENSG00000168036 ENSG00000132849 ENSG00000072415 PMC8615762__F1 Chemokine Pathways in Cutaneous Melanoma: Their Modulation by Cancer and Exploitation by the Clinician ENSG00000108702 ENSG00000163464 ENSG00000019991 ENSG00000102962 ENSG00000179934 ENSG00000107562 ENSG00000163739 ENSG00000138798 ENSG00000124875 ENSG00000121807 ENSG00000121966 ENSG00000131142 ENSG00000138755 ENSG00000163734 ENSG00000169429 ENSG00000112486 ENSG00000081041 ENSG00000184451 ENSG00000277943 ENSG00000169245 ENSG00000186810 ENSG00000108691 ENSG00000137077 ENSG00000102970 ENSG00000126353 ENSG00000115009 PMC5574038__F6 The role of the Dishevelled DEP domain in Wnt/Beta-catenin signal transduction ENSG00000154342 ENSG00000281324 ENSG00000168036 PMC7721491__F4 Association of PPARs with neuroinflammation ENSG00000111537 PMC6976994__F3 Mechanistic aspects of DME regulation in mouse liver tumors with mutations in either the Ctnnb1, Hras, or Braf oncogene ENSG00000130649 ENSG00000168036 ENSG00000140465 ENSG00000106546 PMC9228804__F3 Tumor Suppressive Effects of GAS5 in Cancer Cells ENSG00000198793 ENSG00000123374 PMC3882755__F8 A Receptor-Specific Function for Notch2 in Mediating Vascular Smooth Muscle Cell Growth Arrest Through p27kip1 ENSG00000145604 ENSG00000123374 PMC5466396__F9 Crosstalk of hypoxia-induced endothelial-mesenchymal transition (EndMT) signaling pathways ENSG00000148400 ENSG00000020633 PMC9228804__F6 Tumor Suppressive Effects of GAS5 in Cancer Cells ENSG00000198793 PMC4682189__F2 Comparative transcriptome analysis of grapevine in response to copper stress ENSG00000080819 ENSG00000126088 ENSG00000188690 ENSG00000127948 PMC8755416__F2 Renal consequences of the novel coronavirus disease 2019 (COVID-19) and hydrogen sulfide as a potential therapy ENSG00000130234 ENSG00000125538 PMC3184987__F5 Activation-Induced Cytidine Deaminase (AID)-Associated Multigene Signature to Assess Impact of AID in Etiology of Diseases with Inflammatory Component ENSG00000177455 ENSG00000170458 ENSG00000198851 ENSG00000140968 ENSG00000122877 ENSG00000196092 ENSG00000291905 ENSG00000283060 ENSG00000158869 PMC9181689__F2 Enhancing the Therapeutic Potential of Mesenchymal Stromal Cell-Based Therapies with an Anti-Fibrotic Agent for the Treatment of Chronic Kidney Disease ENSG00000125538 PMC5465356__F8 ATP-binding cassette transporter A1 regulates phosphoantigen release and VG9VD2 T cell activation by dendritic cells ENSG00000198793 ENSG00000197429 PMC4991739__F5 Dynamically alternative pathway network ENSG00000164879 ENSG00000041982 ENSG00000186716 ENSG00000087842 PMC7161696__F9 Pathway of hyphal formation ENSG00000196511 ENSG00000070831 ENSG00000166407 PMC3091753__F3 Representative genes that responded to [BF/S+L/Ep] treatment ENSG00000162889 ENSG00000126016 ENSG00000170909 ENSG00000081041 ENSG00000134982 ENSG00000109320 ENSG00000155926 ENSG00000197632 ENSG00000269335 ENSG00000163736 ENSG00000100206 ENSG00000179915 ENSG00000110693 ENSG00000164163 ENSG00000128791 ENSG00000132326 ENSG00000197386 ENSG00000185591 ENSG00000154654 ENSG00000114115 ENSG00000278693 PMC5345753__F1 Different molecular mechanisms that can induce time-delay necessary for the generation of oscillations in transcription factor activity ENSG00000168036 ENSG00000114315 ENSG00000168646 PMC6668488__F7 A proposed schematic representation of Mn-dependent adaptive and toxic response pathways ENSG00000101247 ENSG00000242247 ENSG00000137845 PMC8325099__F7 Identification of novel biomarkers for arthrofibrosis after total knee arthroplasty in animal models and clinical patients ENSG00000163914 PMC3709248__F4 Nitr9L–Dap12 activation of cytotoxic cells ENSG00000291603 ENSG00000291971 ENSG00000010810 PMC1933158__F6 A hypothetical model for the dual roles of insulin signaling in human brain ENSG00000178403 ENSG00000136997 ENSG00000119912 PMC8306439__F3 Combining Oncolytic Viruses and Small Molecule Therapeutics: Mutual Benefits ENSG00000169047 ENSG00000198793 PMC3145614__F1 Genetic Loci Associated with Plasma Phospholipid n-3 Fatty Acids: A Meta-Analysis of Genome-Wide Association Studies from the CHARGE Consortium ENSG00000134824 ENSG00000149485 ENSG00000197977 PMC5601173__F3 SOCS molecules: the growing players in macrophage polarization and function ENSG00000138378 ENSG00000105397 ENSG00000110324 ENSG00000105639 ENSG00000168610 PMC4222248__F7 EGF signaling pathway to stimulate proliferation of conjunctival goblet cells ENSG00000291971 ENSG00000138798 PMC9496100__F3 Ginsenoside and Its Therapeutic Potential for Cognitive Impairment ENSG00000002330 ENSG00000198793 ENSG00000139687 ENSG00000140443 PMC7325921__F2 Quantification of intracellular carbon energy metabolism ENSG00000262785 ENSG00000159224 ENSG00000173599 ENSG00000124253 PMC11617210__F10 ADRB2 serves as a novel biomarker and attenuates alcoholic hepatitis via the SIRT1/PGC-1A/PPARA pathway: integration of WGCNA, machine learning and experimental validation ENSG00000169245 ENSG00000108691 ENSG00000169429 ENSG00000096717 PMC3764486__F2 Expanding roles for CD4+ T cells in immunity to viruses ENSG00000139193 PMC4785262__F3 Neutrophil Functions in Periodontal Homeostasis ENSG00000198742 ENSG00000172005 ENSG00000172936 PMC7542236__F1 PI3K/Akt/mTORC1 pathway, Ras/Raf/MEK/ERK pathway, mTORC2 signaling, and the EMT process ENSG00000291971 ENSG00000169047 PMC4380230__F2 Endothelial cell metabolism in normal and diseased vasculature ENSG00000143799 ENSG00000228716 ENSG00000113492 ENSG00000113161 PMC9181642__F8 Angiotensin II Inhibits Insulin Receptor Signaling in Adipose Cells ENSG00000005882 PMC3916982__F2 Crosstalk of signaling pathways in breast cancer and the potential clinical therapeutic targets ENSG00000002330 ENSG00000166278 ENSG00000171791 ENSG00000146648 ENSG00000196712 PMC8517487__F10 Expression of Microtubule-Associated Proteins in Relation to Prognosis and Efficacy of Immunotherapy in Non-Small Cell Lung Cancer ENSG00000149311 ENSG00000175054 ENSG00000002330 ENSG00000179091 ENSG00000134982 ENSG00000135114 ENSG00000132326 ENSG00000123374 ENSG00000117335 PMC8526928__F2 Rhinovirus Immunity and Asthma ENSG00000213928 ENSG00000105397 ENSG00000115415 PMC2677387__F1 mTORC1 activation by nutrients and growth factors ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC4324736__F3 Individual involvement of the products of the eight studied genes (shown in red colour) in the (a) RAS/RAF/MEK/MAPK, (b) PI3K/AKT, and (c) GNAQ/11 signalling transduction pathways ENSG00000157764 ENSG00000198793 ENSG00000088256 PMC7247819__F2 Activation and inhibition of the AIM2 and NLRP3 inflammasome in SLE, Ps, AD, and vitiligo ENSG00000162711 ENSG00000196576 ENSG00000163568 ENSG00000113525 PMC5669850__F1 Role of the inflammasome in chronic obstructive pulmonary disease (COPD) ENSG00000239732 ENSG00000167207 ENSG00000080345 ENSG00000187554 ENSG00000150455 ENSG00000175104 ENSG00000106100 ENSG00000164342 PMC10530962__F2 Progress in Regenerative Medicine: Exploring Autologous Platelet Concentrates and Their Clinical Applications PMC6000455__F1 mTOR信号通路mTOR signaling pathway ENSG00000138798 ENSG00000169047 PMC8484528__F5 Integrated Analysis and Finding Reveal Anti–Liver Cancer Targets and Mechanisms of Pachyman (Poria cocos Polysaccharides) ENSG00000081237 ENSG00000291971 ENSG00000138798 ENSG00000100985 ENSG00000112715 ENSG00000168610 ENSG00000164305 ENSG00000121966 ENSG00000163631 PMC6701435__F5 KEGG pathway analysis for HepG2 cells depicting the upregulated genes in the TNF signaling pathway after the treatment with TIT3; the altered genes are marked ENSG00000149968 ENSG00000078747 ENSG00000102871 ENSG00000157227 ENSG00000188404 ENSG00000007908 ENSG00000128342 ENSG00000168040 ENSG00000168404 ENSG00000163295 ENSG00000026103 PMC6337474__F1 Top left: Wnt binds to the Frizzled receptor (Fz) and the LRP5/6 co-receptor ENSG00000178860 ENSG00000152266 ENSG00000168036 PMC9181207__F1 Molecular Basis of Bile Acid-FXR-FGF15/19 Signaling Axis ENSG00000138135 ENSG00000276559 ENSG00000167910 ENSG00000036530 ENSG00000180432 ENSG00000115271 ENSG00000135929 PMC2782725__F2 Cell cycle and acute kidney injury PMC8607431__F7 Integrin-Src-YAP1 signaling mediates the melanoma acquired resistance to MAPK and PI3K/mTOR dual targeted therapy ENSG00000157764 ENSG00000291971 ENSG00000198793 PMC8237188__F1 JAK selectivity and the implications for clinical inhibition of pharmacodynamic cytokine signalling by filgotinib, upadacitinib, tofacitinib and baricitinib ENSG00000111537 ENSG00000105397 ENSG00000105639 PMC11941543__F2 Influenza virus interaction with autophagy ENSG00000198793 PMC7493230__F4 Proposed mechanism for the EGFR/c-Met-mTOR/S6K signaling axis in NSCLC ENSG00000019991 ENSG00000162337 ENSG00000138798 ENSG00000175592 ENSG00000168036 ENSG00000146648 PMC6937862__F2 The graphical user interface and output of ZDOG ENSG00000104812 ENSG00000140992 ENSG00000002330 ENSG00000153094 ENSG00000169047 ENSG00000198793 ENSG00000134308 ENSG00000115904 ENSG00000214827 ENSG00000108443 ENSG00000150093 ENSG00000167965 ENSG00000141564 ENSG00000171791 ENSG00000121879 ENSG00000012048 ENSG00000177455 ENSG00000103479 ENSG00000136997 ENSG00000123374 ENSG00000160447 ENSG00000132906 ENSG00000119535 ENSG00000109320 ENSG00000108342 ENSG00000213341 ENSG00000107175 ENSG00000160741 ENSG00000187840 ENSG00000151276 ENSG00000117020 ENSG00000040199 ENSG00000184371 ENSG00000124253 PMC5427079__F6 Reactome pathways displayed in Figure were converted into a functional interaction network using FI network view ENSG00000213420 ENSG00000168928 ENSG00000134827 ENSG00000100258 ENSG00000138823 ENSG00000162438 ENSG00000169439 ENSG00000175899 ENSG00000076716 ENSG00000158874 ENSG00000175336 PMC5427079__F5 Enriched pathway analysis: The entities in the diagram colored purple are hits within positive gene list ENSG00000116266 PMC10739988__F2 Advance of the third‑generation EGFR‑TKI in the treatment of non‑small cell lung cancer (Review) ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC7709261__F1 Outline of TGFB signaling pathway regulating HCC initiation and progression ENSG00000167601 ENSG00000153283 ENSG00000170558 ENSG00000132646 ENSG00000136997 ENSG00000026508 ENSG00000168036 ENSG00000100985 ENSG00000168610 ENSG00000146648 ENSG00000137801 PMC1767116__F3 Mitochondrial death signalling pathways ENSG00000002330 PMC7709261__F2 Function of lncRNAs in regulating TGFB signaling pathway to affect HCC tumorigenesis ENSG00000171345 PMC10657592__F1 Connective tissue growth factor: Role in trabecular meshwork remodeling and intraocular pressure lowering ENSG00000138798 ENSG00000198670 ENSG00000175104 PMC8567041__F4 Integrative multi‐omics approach for mechanism of humidifier disinfectant‐associated lung injury ENSG00000087245 PMC8522789__F1 Clinical and Mechanistic Characteristics of Current JAK Inhibitors in IBD ENSG00000105397 ENSG00000154059 ENSG00000113525 PMC8674945__F1 Soluble Urokinase Plasminogen Activator Receptor (suPAR) as a Biomarker of Systemic Chronic Inflammation ENSG00000291971 ENSG00000092199 ENSG00000122194 ENSG00000132693 PMC4607752__F5 BaP effects on the expression of BaP marker genes and genes involved in the AHR signaling pathway ENSG00000142192 ENSG00000116044 ENSG00000163064 ENSG00000168610 ENSG00000048740 ENSG00000106546 ENSG00000137801 ENSG00000066468 ENSG00000137204 ENSG00000092054 ENSG00000132205 ENSG00000019549 ENSG00000198728 ENSG00000100439 ENSG00000172915 ENSG00000142149 ENSG00000005381 PMC10725447__F0 Upregulation of FAM83F by c-Myc promotes cervical cancer growth and aerobic glycolysis via Wnt/Beta-catenin signaling activation ENSG00000134982 ENSG00000168036 ENSG00000133477 PMC5434467__F1 The structure of IL-35 and the activation of the JAK-STAT signaling pathway ENSG00000138378 ENSG00000115415 ENSG00000105246 PMC5814839__F8 P53 signaling pathway targeted by hsa-mir-34a in liver cancer ENSG00000112576 ENSG00000105327 ENSG00000149212 ENSG00000085117 ENSG00000196470 ENSG00000164305 ENSG00000149311 ENSG00000175054 ENSG00000172667 ENSG00000177595 ENSG00000134574 ENSG00000078900 ENSG00000135446 ENSG00000171848 ENSG00000112378 ENSG00000177519 ENSG00000105810 ENSG00000120868 ENSG00000149547 ENSG00000026103 ENSG00000198625 PMC8568984__F4 Cross-platform transcriptomic profiling of the response to recombinant human erythropoietin ENSG00000074410 ENSG00000004939 PMC6714137__F11 Schematic representation of inhibitory effect of miR‐539 on EMT and metastasis of PCa PMC10173380__F7 Schematic diagram illustrating the mechanisms through which VNN1 in PC cells induces Beta-cell dedifferentiation by inhibiting the AMPK/GAPDH/Sirt1/FoxO1 signaling pathway ENSG00000150907 ENSG00000096717 ENSG00000112299 PMC6966464__F2 Four ErbB receptors ENSG00000002330 ENSG00000065361 ENSG00000163235 ENSG00000291971 ENSG00000113070 ENSG00000129946 ENSG00000138798 ENSG00000198793 ENSG00000158458 ENSG00000178568 PMC2195865__F1 Extrinsic and intrinsic cell death signaling pathways ENSG00000168040 PMC5759086__F3 Metabologenomics of Phaeochromocytoma and Paraganglioma: An Integrated Approach for Personalised Biochemical and Genetic Testing ENSG00000123454 ENSG00000141744 PMC6379280__F2 Rationale for choosing Arl13b, SMO, and melanin-concentrating hormone receptor 1 (MCHR1) as cilia-targeting moieties ENSG00000169379 ENSG00000164690 ENSG00000128602 ENSG00000128285 PMC4082763__F1 Protein Prenylation and Synaptic Plasticity: Implications for Alzheimer’s Disease ENSG00000163914 ENSG00000197429 PMC8883943__F1 D-Amino Acids as a Biomarker in Schizophrenia ENSG00000182346 PMC9693569__F1 Polyphenols for Livestock Feed: Sustainable Perspectives for Animal Husbandry? ENSG00000180245 ENSG00000197429 ENSG00000291720 PMC11891048__F2 S-palmitoylation is involved in immune response types ENSG00000175893 ENSG00000163958 ENSG00000135218 ENSG00000153786 ENSG00000160446 ENSG00000134982 ENSG00000099864 ENSG00000168040 ENSG00000136247 ENSG00000163812 ENSG00000156599 ENSG00000168610 ENSG00000188818 ENSG00000213658 ENSG00000284099 ENSG00000124181 ENSG00000099904 PMC7600636__F2 Canonical pathway of STAT3 signaling ENSG00000291971 ENSG00000168610 PMC2820477__F2 Scheme of known Wnt pathways ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000070831 ENSG00000143878 ENSG00000134982 PMC3675900__F2 Eicosanoids in Metabolic Syndrome ENSG00000135218 ENSG00000134824 ENSG00000149485 PMC2996902__F1 CoQ10 biosynthesis pathway ENSG00000132423 ENSG00000119723 ENSG00000110871 ENSG00000148459 ENSG00000173085 ENSG00000167186 PMC12075257__F7 Schematic model showing the role of WED in regulating megakaryocyte differentiation and platelet generation ENSG00000102145 PMC2820477__F1 Schematic junctional organization and Beta-catenin signaling in CNS ECs: comparison of brain and retina ENSG00000149564 ENSG00000106025 ENSG00000173599 ENSG00000168036 PMC3962112__F1 Biosensor-derived promoters upstream of modules B and C to control the expression of fadD and atfA, and the ethanol biosynthetic pathway (adhB and pdc), respectively ENSG00000168040 ENSG00000026103 PMC10620831__F8 PRMTs regulate antiviral innate immunity ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000164169 ENSG00000163565 ENSG00000126457 ENSG00000132600 ENSG00000136869 ENSG00000198890 ENSG00000175104 PMC5488238__F6 BMP–Notch interaction in intestinal homeostasis and CRC disease subtypes ENSG00000283780 ENSG00000283060 ENSG00000204217 ENSG00000125968 PMC7075948__F1 Interferon (IFN) signaling enhancement by the inhibition of the Wnt pathway through miR-34 ENSG00000183735 PMC7492298__F6 Granulosa cells undergoing apoptosis ENSG00000132906 ENSG00000153094 ENSG00000168040 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC7836322__F2 Replication cycle of HCoV ENSG00000197635 ENSG00000130234 PMC9574713__F7 Temporal Alterations of Sphingolipids in Optic Nerves After Indirect Traumatic Optic Neuropathy ENSG00000070610 ENSG00000148154 ENSG00000174607 PMC6757160__F2 General mechanism of SYK activation and SYK-mediated signaling: a pathway demonstrating the involving of downsignaling associated with SYK activation ENSG00000162711 ENSG00000001626 PMC6705574__F8 The mechanisms underlying contributions of YAP/TAZ/Beta-catenin to the spinal central sensitization after nerve injury and regulation of dCTB on YAP/TAZ/Beta-catenin and Hippo signaling pathways ENSG00000134982 ENSG00000168036 ENSG00000198670 ENSG00000150457 ENSG00000131023 PMC7018500__F1 Signaling pathways involved in the recognition of HSV ENSG00000213928 ENSG00000239732 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000276561 ENSG00000164342 PMC11016017__F3 Cell plasticity modulation by flavonoids in resistant breast carcinoma targeting the nuclear factor kappa B signaling ENSG00000149311 ENSG00000175054 ENSG00000198793 ENSG00000272398 ENSG00000026508 ENSG00000077463 ENSG00000146648 PMC7607115__F2 Model for TERT promoter mutations, TERT expression and telomerase activation during the pathogenesis of TC ENSG00000157764 ENSG00000164362 ENSG00000165409 PMC5720788__F1 Systematic integrative analysis of gene expression identifies HNF4A as the central gene in pathogenesis of non-alcoholic steatohepatitis ENSG00000148798 ENSG00000026103 PMC4545213__F4 Mammalian molecular clock and oscillation of mRNA and protein in peripheral tissues ENSG00000005812 ENSG00000132326 PMC8235534__F1 Understanding the Central Role of Citrate in the Metabolism of Cancer Cells and Tumors: An Update ENSG00000180210 ENSG00000131473 ENSG00000173599 ENSG00000124253 ENSG00000026103 PMC11968292__F3 Keap1-dependent and Keap1-independent regulatory pathways of Nrf2 ENSG00000106546 ENSG00000079999 PMC8035078__F1 LTA synthesis, models for the cross-membrane d-alanine modification process and examples of WTA and complex SCWP synthesis pathways ENSG00000226275 ENSG00000069482 PMC6207586__F6 Mechanism of action of microtitre plate based complement activation assays ENSG00000039537 ENSG00000113600 PMC8397452__F6 Multifaceted Roles of Proline in Cell Behavior ENSG00000128272 ENSG00000143768 ENSG00000243709 ENSG00000162878 ENSG00000100033 PMC3039745__F1 TRAF6 and A20 control K63-linked ubiquitination of Beclin 1 to trigger autophagy ENSG00000136869 ENSG00000171791 ENSG00000175104 PMC9569951__F1A Roles of Androgens in Humans: Biology, Metabolic Regulation and Health ENSG00000157005 PMC4292866__F11 Naproxen Induces Type X Collagen Expression in Human Bone-Marrow-Derived Mesenchymal Stem Cells Through the Upregulation of 5-Lipoxygenase PMC2941735__F2 Targeting Non-Homologous End-Joining Through Epidermal Growth Factor Receptor Inhibition: Rationale and Strategies for Radiosensitization ENSG00000163235 ENSG00000138798 ENSG00000146648 PMC2938833__F2 Actin-cytoskeleton signaling pathway and the candidate genes involved in colorectal cancer progression in patients with ulcerative colitis ENSG00000180210 ENSG00000076928 ENSG00000175866 ENSG00000170458 ENSG00000138443 ENSG00000138798 ENSG00000196914 PMC2938833__F3 Pfn gene neighborhood and its interacting pathway ENSG00000112290 ENSG00000176732 ENSG00000196570 PMC6127659__F1 Long non-coding RNAs affect epithelial-mesenchymal transition in gastric cancer cells ENSG00000019991 ENSG00000168036 ENSG00000074266 ENSG00000100985 ENSG00000178691 ENSG00000196363 PMC4190549__F1 The PI3K/Akt/mTOR pathway ENSG00000002330 ENSG00000198793 ENSG00000026103 PMC4467582__F7 Proposed schema of the pathways underlying renal protection conferred by xenon (Xe) preconditioning PMC5362547__F1 Hippo signaling pathway provides novel anti-cancer drug targets ENSG00000167601 ENSG00000114978 ENSG00000150457 ENSG00000131023 PMC8277576__F5 Steroids on T lymphocytes ENSG00000160224 ENSG00000049768 PMC9237470__F1 Basal Cell Carcinoma and Hedgehog Pathway Inhibitors: Focus on Immune Response ENSG00000164690 ENSG00000128602 PMC11800603__F2 Innervation in gliomas promotes tumor growth ENSG00000291971 ENSG00000198793 PMC9237470__F2 Basal Cell Carcinoma and Hedgehog Pathway Inhibitors: Focus on Immune Response ENSG00000128602 PMC10967436__F7 ROS modulation of the Keap1-Nrf2-ARE signaling pathway ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC11800603__F3 Several example mechanisms of therapeutic avenues of cancer neuroscience: A Inhibit of ADAM10/NLGN3 can suppress glioma growth by targeting its downstream PI3K-mTOR signaling pathway ENSG00000137845 PMC8481821__F2 Neu Perspectives, Therapies, and Challenges for Metastatic HER2-Positive Breast Cancer ENSG00000002330 ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000198793 PMC4613661__F1 Model for KSHV v-cyclin-induced dysregulation of Notch signaling during lymphomagenesis ENSG00000112576 ENSG00000074181 ENSG00000105810 ENSG00000114315 PMC3653035__F1 Beta-Catenin plays two main functions in the cell ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3653035__F2 Wnt ligands induce diverse Wnt pathways ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000163914 ENSG00000168036 PMC3516764__F9 Model for the involvement of the RA in neuronal differentiation ENSG00000129474 ENSG00000096717 PMC2726781__F1 Retromer sorting pathway is made up of a coat complex that binds and transports transmembrane receptors between the endosome and the trans-Golgi network (TGN) ENSG00000003056 ENSG00000142192 ENSG00000111237 ENSG00000069329 ENSG00000162896 PMC3314478__F1 Parkinson’s disease: don’t mess with calcium ENSG00000128272 ENSG00000144935 ENSG00000167323 ENSG00000198793 PMC10759737__F6 RPTOR blockade suppresses brain metastases of NSCLC by interfering the ceramide metabolism via hijacking YY1 binding ENSG00000100811 ENSG00000063176 ENSG00000198793 ENSG00000141564 ENSG00000168610 PMC4721539__F1 Dissecting Germ Cell Metabolism through Network Modeling ENSG00000172828 ENSG00000121207 ENSG00000175535 ENSG00000003137 ENSG00000130164 ENSG00000153823 ENSG00000140505 ENSG00000198691 ENSG00000292155 ENSG00000079435 ENSG00000262243 PMC7319280__F7 Systematic approach to decipher crosstalk in the p53 signaling pathway using single cell dynamics ENSG00000149311 ENSG00000099985 PMC7369811__F7 Scheme of the potential IR-induced EGFR/NFKB–RIP1–Src–STAT3–EMT pathway ENSG00000291971 ENSG00000168610 ENSG00000146648 PMC7232439__F1 Schematic diagram for activation of innate immune responses and interferon (IFN) signaling pathway after influenza A virus (IAV) infection ENSG00000162711 ENSG00000213928 ENSG00000088888 ENSG00000138135 ENSG00000105397 ENSG00000276561 ENSG00000164342 PMC5075576__F2 Complement-dependent cytotoxicity and inflammation ENSG00000236625 PMC6449645__F1 (A1) GPCRs induce GAq dependent c-Src activation at the plasma membrane and tyrosine phosphorylation of NEDD4-2, releasing NEDD4-2 auto-inhibition ENSG00000069869 ENSG00000291971 ENSG00000166278 PMC4851164__F3 Network modeling of TGFB signaling in hepatocellular carcinoma epithelial-to-mesenchymal transition reveals joint Sonic hedgehog and Wnt pathway activation ENSG00000019991 ENSG00000169554 ENSG00000070831 ENSG00000291971 ENSG00000138798 ENSG00000131778 ENSG00000176692 ENSG00000124216 ENSG00000122691 ENSG00000149269 ENSG00000019549 ENSG00000026508 ENSG00000164690 ENSG00000128602 ENSG00000168646 ENSG00000146648 ENSG00000140443 PMC4743039__F8 Bidirectional synaptic structural plasticity after chronic cocaine administration occurs through Rap1 small GTPase signaling ENSG00000198793 ENSG00000172005 PMC4491987__F6 Effect of the combination of rapamycin and resveratrol on the PI3K/Akt/mTORC1 signaling pathway ENSG00000169047 PMC4851164__F7 Network modeling of TGFB signaling in hepatocellular carcinoma epithelial-to-mesenchymal transition reveals joint Sonic hedgehog and Wnt pathway activation ENSG00000124216 ENSG00000164690 ENSG00000128602 PMC4398700__F3 Ingenuity® Pathways Analysis reveals a possible network of genes activated in IEC-6 cells upon induction of the ephrin-B pathway ENSG00000117525 ENSG00000137193 ENSG00000185591 ENSG00000162772 ENSG00000114315 ENSG00000073756 ENSG00000166147 ENSG00000106546 PMC3156249__F1 B-Myb, Cancer, Senescence, and MicroRNAs ENSG00000145604 ENSG00000123374 ENSG00000205250 PMC4731824__F8 Novel NFKB/YY1/microRNA-10a regulatory circuit in fibroblast-like synoviocytes regulates inflammation in rheumatoid arthritis ENSG00000100811 ENSG00000166167 ENSG00000102871 ENSG00000173039 ENSG00000172936 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC3039968__F2 Regulatory Processes Linked to PL Metabolism ENSG00000166278 PMC11794924__F3 Molecular mechanisms of granulomatous inflammation for sarcoidosis; Antigen-presenting cells, like macrophages and dendritic cells, initiate phagocytosis of antigens ENSG00000186810 ENSG00000105397 ENSG00000137033 ENSG00000115415 ENSG00000198793 ENSG00000049768 ENSG00000168610 ENSG00000073861 ENSG00000115009 ENSG00000112486 PMC8210588__F5 Triptolide: pharmacological spectrum, biosynthesis, chemical synthesis and derivatives ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC9661764__F5 ERAlpha-NRF2 signalling axis promotes bicalutamide resistance in prostate cancer ENSG00000157554 ENSG00000026508 ENSG00000118777 ENSG00000023839 PMC9197233__F5 Mechanical Strain Induces Transcriptomic Reprogramming of Saphenous Vein Progenitors ENSG00000104899 ENSG00000133937 ENSG00000070831 ENSG00000115297 ENSG00000156574 ENSG00000065559 ENSG00000180806 ENSG00000171791 ENSG00000169032 ENSG00000276561 ENSG00000170365 ENSG00000164093 ENSG00000157450 ENSG00000102935 PMC2854141__F9 Uncovering Molecular Biomarkers That Correlate Cognitive Decline with the Changes of Hippocampus' Gene Expression Profiles in Alzheimer's Disease ENSG00000105329 ENSG00000291971 ENSG00000138798 ENSG00000171791 ENSG00000157557 ENSG00000245848 ENSG00000136997 ENSG00000150907 ENSG00000113520 ENSG00000185591 ENSG00000155657 ENSG00000196712 ENSG00000026103 ENSG00000100285 ENSG00000108342 ENSG00000182621 ENSG00000168610 ENSG00000178127 ENSG00000277586 ENSG00000185946 ENSG00000186716 ENSG00000177606 ENSG00000184371 ENSG00000129152 ENSG00000146648 PMC7892446__F2 Mechanisms by which SARS-CoV-2 promotes muscle wasting and sarcopenia ENSG00000130234 ENSG00000198793 ENSG00000140443 PMC6966687__F3 Networks presenting the functional protein-protein interactions of the (A) 97 down- and (C) 67 upregulated proteins related to the GO term “protein phosphorylation” (GO:0006468) ENSG00000030304 ENSG00000198793 ENSG00000164327 ENSG00000087586 ENSG00000143322 ENSG00000150457 ENSG00000079435 ENSG00000128602 ENSG00000062524 ENSG00000135605 ENSG00000120539 ENSG00000163788 PMC7352245__F3 Canonical and alternative NFKB signaling pathways ENSG00000023445 ENSG00000104856 ENSG00000105369 ENSG00000110330 ENSG00000109320 ENSG00000007312 ENSG00000173039 ENSG00000111321 ENSG00000127191 ENSG00000010671 ENSG00000186716 ENSG00000131323 ENSG00000198286 PMC7759744__F1 Mitochondrial dynamics and bioenergetics in inflammatory astrocytes and neurological disorders ENSG00000116688 ENSG00000005882 PMC9495339__F3 Nrf2 in Pulmonary Fibrosis: Molecular Mechanisms and Treatment Approaches ENSG00000185022 ENSG00000181019 ENSG00000100387 ENSG00000198517 ENSG00000197063 ENSG00000105227 ENSG00000079999 PMC7017485__F4 Ingenuity Pathway Analysis showing the plasma membrane and extracellular proteins directly related to YAP1 ENSG00000175206 ENSG00000135218 ENSG00000281324 ENSG00000087077 ENSG00000132849 ENSG00000137801 ENSG00000154864 ENSG00000185518 ENSG00000148498 ENSG00000172260 ENSG00000186575 ENSG00000162572 ENSG00000205476 ENSG00000107186 ENSG00000188157 ENSG00000150054 ENSG00000285136 ENSG00000140443 ENSG00000198947 ENSG00000126016 ENSG00000142192 ENSG00000109321 ENSG00000163453 ENSG00000173402 ENSG00000102854 ENSG00000162692 ENSG00000146648 ENSG00000178568 ENSG00000103335 PMC7698885__F6 PNPLA3 I148M promotes activation of HH signaling and its downstream target Yap ENSG00000109321 ENSG00000100344 ENSG00000103241 PMC8750789__F2 AUTS2 Gene: Keys to Understanding the Pathogenesis of Neurodevelopmental Disorders ENSG00000070831 ENSG00000062598 ENSG00000112139 ENSG00000158321 ENSG00000180628 ENSG00000115525 PMC10887023__F2 Gene interaction network of dyslexia and stress-associated genes ENSG00000166448 ENSG00000153815 ENSG00000082397 ENSG00000160299 ENSG00000085662 ENSG00000169860 ENSG00000205693 ENSG00000183638 ENSG00000115364 ENSG00000100109 ENSG00000136235 ENSG00000281818 ENSG00000137261 ENSG00000157514 ENSG00000146038 ENSG00000101752 ENSG00000101189 ENSG00000142687 PMC3696556__F4 CD4+ follicular helper T cell infiltration predicts breast cancer survival ENSG00000139193 ENSG00000137078 ENSG00000203896 ENSG00000280962 ENSG00000088179 ENSG00000163599 ENSG00000162924 ENSG00000117020 ENSG00000110395 ENSG00000213658 ENSG00000156127 ENSG00000010810 ENSG00000177606 ENSG00000076641 ENSG00000124181 PMC4529918__F1 An illustration representing microRNAs (miRNAs) and their targets involved in EGFR signaling pathway in lung cancer and anti-EGFR therapy ENSG00000105722 ENSG00000157764 ENSG00000198793 ENSG00000136997 ENSG00000146648 PMC3696556__F5 CD4+ follicular helper T cell infiltration predicts breast cancer survival ENSG00000139193 ENSG00000137078 ENSG00000134460 ENSG00000291603 ENSG00000088179 ENSG00000152495 ENSG00000091972 ENSG00000163519 ENSG00000167323 ENSG00000163599 ENSG00000109943 ENSG00000162924 ENSG00000154016 ENSG00000188389 ENSG00000117020 ENSG00000213658 ENSG00000138166 ENSG00000156127 ENSG00000010810 ENSG00000177606 ENSG00000076641 ENSG00000049249 ENSG00000113263 ENSG00000198286 PMC7290974__F4 Altering host gene expression by disrupting transcriptional regulators ENSG00000172936 ENSG00000175104 ENSG00000140464 PMC5179328__F3 TLR signaling pathway and ENU-induced mutations that impair TLR-dependent TNF or type I IFN secretion ENSG00000213928 ENSG00000135218 ENSG00000150455 ENSG00000110057 ENSG00000183735 ENSG00000239732 ENSG00000136869 ENSG00000168404 ENSG00000164342 ENSG00000174125 ENSG00000288445 ENSG00000129667 ENSG00000111727 ENSG00000139370 ENSG00000125347 ENSG00000276561 ENSG00000047579 ENSG00000226275 ENSG00000170458 ENSG00000187554 ENSG00000128829 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC11758815__F8 Iron signaling ENSG00000170365 ENSG00000182511 ENSG00000090674 ENSG00000105697 ENSG00000026508 PMC7290974__F1 Toll-like receptors (TLR) and nucleotide-binding domain and leucine-rich repeat (NLR) receptor signaling in response to L ENSG00000167207 ENSG00000172936 ENSG00000175104 ENSG00000106100 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC11758815__F9 Copper signaling ENSG00000173992 ENSG00000198793 ENSG00000123191 ENSG00000139508 ENSG00000177556 ENSG00000026508 ENSG00000120509 ENSG00000087250 ENSG00000146648 PMC3406594__F8 Schematic model showing role of AMPKA1 as an upstream kinase of TAK1 in TLR4-mediated signaling pathway ENSG00000172005 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC7900430__F2 Mechanism of the inhibitory role of Wnt/Beta-catenin pathway in preadipocytes during adipogenesis ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8307089__F1 Intersection of Two Checkpoints: Could Inhibiting the DNA Damage Response Checkpoint Rescue Immune Checkpoint-Refractory Cancer? ENSG00000175054 ENSG00000183735 ENSG00000111537 ENSG00000189403 PMC7829553__F1 Currently known CoA-dependent enzymatic reactions and transporters in human peroxisomes ENSG00000176894 ENSG00000276559 ENSG00000140876 ENSG00000095321 ENSG00000105516 ENSG00000161533 ENSG00000213965 ENSG00000117528 ENSG00000173208 ENSG00000116906 ENSG00000005469 PMC7829553__F2 Currently known NAD+/NADH- and NADP+/NADPH-dependent peroxisomal enzymatic reactions, transport of NAD+/NADH, NADP+/NADPH, NMNH+, AMP, and 2′,5′-ADP, and role of shuttle systems ENSG00000274296 ENSG00000142655 ENSG00000176894 ENSG00000105516 ENSG00000288217 ENSG00000112874 ENSG00000162928 PMC7829553__F3 Currently known FAD, PLP, ThPP, FMN, and heme-dependent enzymatic reactions in the peroxisomes and transport of FAD, PLP, ThPP, heme, FMN and AMP ENSG00000142655 ENSG00000288217 ENSG00000112874 ENSG00000162928 PMC8312441__F7 Methylation silencing CDH23 is a poor prognostic marker in diffuse large B-cell lymphoma ENSG00000166341 ENSG00000123975 ENSG00000205250 ENSG00000074276 ENSG00000107736 ENSG00000139880 ENSG00000124762 ENSG00000253159 ENSG00000291681 ENSG00000079112 ENSG00000124215 ENSG00000103479 ENSG00000291676 ENSG00000186575 ENSG00000166589 ENSG00000114126 ENSG00000198176 ENSG00000134057 ENSG00000123374 ENSG00000150275 ENSG00000080839 ENSG00000282899 ENSG00000175305 PMC2744356__F1 Toll-like receptors in skin infectious and inflammatory diseases ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC5992788__F1 CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer’s Disease ENSG00000142192 ENSG00000257218 PMC5178148__F2 Hypothetical model depicting a potential role of SMAD3 activation in GCT development ENSG00000117525 ENSG00000285109 ENSG00000101255 ENSG00000150907 PMC7869020__F1 Purine salvage and de novo purine biosynthesis (DNPB) ENSG00000128050 ENSG00000198931 PMC4310752__F1 Therapeutic targeting of cancers with loss of PTEN function ENSG00000051180 PMC2519122__F1 Role of mTOR in anticancer drug resistance ENSG00000169047 ENSG00000196712 PMC4037353__F1 MicroRNA regulation of the germinal center response ENSG00000145321 ENSG00000040199 ENSG00000126353 ENSG00000196498 ENSG00000069667 PMC9104602__F5 ZIKV infection downregulates host mRNA expression in the placenta, including genes associated with cellular function and development ENSG00000161647 ENSG00000112494 ENSG00000121753 ENSG00000089116 ENSG00000169856 ENSG00000262635 ENSG00000053702 ENSG00000169047 ENSG00000179603 ENSG00000145431 ENSG00000188257 ENSG00000110777 ENSG00000276996 ENSG00000171885 ENSG00000136535 ENSG00000153064 ENSG00000204531 ENSG00000010310 ENSG00000067715 ENSG00000106410 ENSG00000159263 ENSG00000143126 ENSG00000205927 ENSG00000163739 ENSG00000137801 ENSG00000161955 ENSG00000149968 ENSG00000148798 ENSG00000111341 ENSG00000118520 ENSG00000123610 ENSG00000182968 ENSG00000007312 ENSG00000104044 ENSG00000275126 ENSG00000111058 ENSG00000122012 ENSG00000186687 ENSG00000181790 ENSG00000170743 ENSG00000123892 ENSG00000103528 ENSG00000167131 ENSG00000102239 ENSG00000188779 ENSG00000080709 ENSG00000214338 ENSG00000189299 ENSG00000111052 ENSG00000165120 PMC3864542__F1A What a Tangled Web We Weave: Emerging Resistance Mechanisms to Inhibition of the Phosphoinositide 3-kinase Pathway ENSG00000169047 PMC8557339__F4 Distinctive clinical presentation and pathogenic specificities of anti-AK5 encephalitis ENSG00000030582 ENSG00000187608 ENSG00000170027 ENSG00000175793 ENSG00000291920 ENSG00000134308 ENSG00000183844 ENSG00000108342 ENSG00000196154 ENSG00000131095 ENSG00000244731 ENSG00000236625 ENSG00000135077 ENSG00000164879 ENSG00000260314 ENSG00000143222 ENSG00000288512 ENSG00000026751 ENSG00000198125 ENSG00000090659 PMC8971730__AF1 CCL18 promotes breast cancer progression by exosomal miR-760 activation of ARF6/Src/PI3K/Akt pathway ENSG00000275385 ENSG00000291971 ENSG00000165527 PMC3281634__F1 Simplified diagram of the unfolded protein response ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC5288713__F6 Epigenetic regulation of nitric oxide synthase 2, inducible (Nos2) by NLRC4 inflammasomes involves PARP1 cleavage ENSG00000091106 ENSG00000007171 PMC7869020__F5 Regulation of de novo Purine Biosynthesis and Purinosome Formation ENSG00000128050 ENSG00000149311 ENSG00000175054 ENSG00000178999 ENSG00000087586 PMC9479340__F1 Tumor accomplice: T cell exhaustion induced by chronic inflammation ENSG00000019991 ENSG00000138798 PMC4497368__F1 The signaling pathway involved in EPO-induced neuroprotection ENSG00000163914 ENSG00000100985 ENSG00000187266 ENSG00000168610 PMC4524753__F2 Diagrammatic sketch shows the hypothetical mechanism of HOTAIR in digestive tract cancers ENSG00000151376 ENSG00000168036 PMC11821962__F4 WWP1-involved signaling pathways and regulatory mechanisms ENSG00000163930 ENSG00000123091 ENSG00000131507 ENSG00000136997 ENSG00000266265 ENSG00000178568 ENSG00000123124 PMC11821962__F5 WWP1 in different types of human cancers ENSG00000087245 ENSG00000163930 ENSG00000198793 ENSG00000131507 ENSG00000266265 ENSG00000197415 ENSG00000168036 ENSG00000150457 ENSG00000131023 ENSG00000168610 ENSG00000196628 ENSG00000123124 ENSG00000154485 ENSG00000136997 ENSG00000105810 ENSG00000100985 PMC9630603__F4 Intersection of stem cell biology and engineering towards next generation in vitro models of human fibrosis ENSG00000178860 PMC9486394__F1 Regulation and coordination of the different DNA damage responses in Drosophila ENSG00000149311 ENSG00000175054 PMC9486394__F2 Regulation and coordination of the different DNA damage responses in Drosophila ENSG00000149311 ENSG00000175054 ENSG00000198408 PMC2901146__F2 Taxol biosynthetic pathway ENSG00000113600 ENSG00000197429 PMC9329401__F7 High protein diet in the induction of sIgA response ENSG00000151882 ENSG00000136869 ENSG00000162896 PMC8031259__F2 Insulin signalling pathway and Insulin resistance in COVID-19 and Diabetes infection.Adapted from Jung & Choi (2014), Finucane and Davenport (2020), Rajpal et al ENSG00000169047 PMC5130286__F3 Working model ENSG00000197713 ENSG00000112715 ENSG00000175104 ENSG00000184216 PMC5923440__F1 MAMP/PAMP sensing pathways in the intestine ENSG00000167207 ENSG00000185187 ENSG00000106100 ENSG00000276561 ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000160703 ENSG00000172936 ENSG00000105483 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC7583738__F1 PTEN in the PI3K/Akt signaling pathway PMC9386306__F10 Oncogenic circular RNA circ_0007534 contributes to paclitaxel resistance in endometrial cancer by sponging miR-625 and promoting ZEB2 expression ENSG00000169554 ENSG00000122691 PMC5384626__F1 Metabolic pathway of retinoic acid ENSG00000095596 ENSG00000187553 ENSG00000184254 ENSG00000003137 ENSG00000121039 ENSG00000128918 ENSG00000162496 PMC3303474__F3 Bibliosphere network of ubiquinol-sensitive genes regulated in liver tissues of C57BL6J mice ENSG00000185591 PMC7145850__F3 Quantitative results of sphingolipids and enzymes by LC-MRM-MS ENSG00000167769 ENSG00000100422 ENSG00000063176 ENSG00000198964 ENSG00000223802 ENSG00000154227 ENSG00000143753 ENSG00000188611 ENSG00000148154 ENSG00000143418 ENSG00000163082 PMC7572682__F2 Lysosome and nucleus interaction in signaling and transcription ENSG00000112561 ENSG00000189298 ENSG00000160741 PMC4903173__F1 Foiling IDOL to help control cholesterol ENSG00000130164 ENSG00000036672 ENSG00000113161 ENSG00000169174 PMC6798117__F9 Model depicting the effects of ZIKV infection on cell cycle progression in hNPCs ENSG00000149311 ENSG00000175054 PMC8112476__F1 Targeting inflammation in atherosclerosis — from experimental insights to the clinic ENSG00000162711 ENSG00000003436 ENSG00000125538 ENSG00000108688 PMC6729001__F7 Schematic model of METTL3 in regulating CRC ENSG00000165819 PMC2783472__F1 Impaired DNA Damage Response – an Achilles’ Heel Sensitizing Cancer to Chemotherapy and Radiotherapy ENSG00000188486 ENSG00000149311 ENSG00000012048 PMC2783472__F2 Impaired DNA Damage Response – an Achilles’ Heel Sensitizing Cancer to Chemotherapy and Radiotherapy ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000123374 ENSG00000140464 PMC6895606__F1 CoA‐dependent activation of mitochondrial acyl carrier protein links four neurodegenerative diseases ENSG00000121897 ENSG00000116353 ENSG00000138621 ENSG00000068120 ENSG00000127125 PMC6714168__F2 The role and proposed mechanism of Wnt5a in psoriatic arthritis ENSG00000169071 ENSG00000163914 PMC10851565__F3 Autophagy’s dual-edge effect on NF-KB and PI resistance ENSG00000104856 ENSG00000149311 ENSG00000177169 ENSG00000102871 ENSG00000172936 ENSG00000157625 ENSG00000162924 ENSG00000083799 ENSG00000154124 ENSG00000162692 ENSG00000145782 ENSG00000184216 PMC12023901__F8 ERS-mediated suppression of ERA expression ENSG00000128272 ENSG00000100219 PMC8268178__F1 Connecting Cholesterol Efflux Factors to Lung Cancer Biology and Therapeutics ENSG00000131748 ENSG00000141458 PMC5110879__F1 MicroRNAs biogenesis and function ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC9329261__F2 Elevated CD4+ T Cell Glucose Metabolism in HIV+ Women with Diabetes Mellitus ENSG00000160883 ENSG00000005882 ENSG00000131828 ENSG00000138400 PMC6418414__F1 The wild-type CARD9 protein consists of an N-terminal caspase activation and recruitment domain (CARD) followed by a coiled-coil domain and a C-terminal tail ENSG00000104856 ENSG00000187796 ENSG00000121058 ENSG00000116525 PMC7015808__F1 Steroidogenic pathway with oxysterols followed in this study.Abbreviations: CHEH – cholesterol epoxide hydrolase, CH25H – cholesterol 25-hydroxylase, CYP – cytochrome P450, DHCR7 – dehydrocholesterol reductase, ROS – reactive oxygen species ENSG00000138135 ENSG00000172893 ENSG00000167910 ENSG00000135929 PMC3147800__F9 Model showing the cooperative function of LMO7 and Rho in the activation of MRTFs ENSG00000163914 ENSG00000136153 ENSG00000198670 PMC8797967__F8 Knockdown of ferritin heavy chain (FTH) inhibits the migration of prostate cancer through reducing S100A4, S100A2, and S100P expression ENSG00000196754 ENSG00000163993 ENSG00000105656 ENSG00000196154 PMC4589691__F6 Regulatory relationships of a KEGG gene set for the human T cell receptor signaling pathway in RegNetwork ENSG00000111537 ENSG00000100906 ENSG00000149269 ENSG00000010810 ENSG00000135446 ENSG00000177606 ENSG00000173039 ENSG00000164400 ENSG00000113520 ENSG00000213341 PMC11853510__F2 Mechanisms of bioactive materials and cytokines in regulating inflammation and maintaining pulp equilibrium through various signaling pathways involving the nucleus [70,71,72,73,74,75,76,77,78] ENSG00000102871 ENSG00000134982 ENSG00000113520 PMC9221615__F9 Endothelial Dysfunction in Acute Hepatic Porphyrias ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000256269 ENSG00000188690 PMC3262938__F2 N-glycan biosynthetic pathways in eukaryotes and glycoengineering ENSG00000214160 PMC10970066__F1 Major components and auxiliary factors of the Notch signaling pathway (modified from ) ENSG00000112576 ENSG00000073614 ENSG00000138798 ENSG00000136997 ENSG00000109670 PMC7927147__F1 Development of opto-BMP system ENSG00000170365 ENSG00000204217 PMC9172199__F3 Comprehensive insight into endothelial progenitor cell-derived extracellular vesicles as a promising candidate for disease treatment ENSG00000074319 ENSG00000110651 ENSG00000010278 ENSG00000135404 ENSG00000165527 PMC3501016__F1 Finding a New Regulator of the Blood Coagulation Cascade♦ ENSG00000003436 ENSG00000149269 PMC10647767__F1 Developments in Genetics: Better Management of Ovarian Cancer Patients ENSG00000149311 ENSG00000012048 ENSG00000144554 ENSG00000051180 ENSG00000139618 ENSG00000183765 PMC9324059__F5 Network Pharmacology and Molecular Docking Elucidate the Underlying Pharmacological Mechanisms of the Herb Houttuynia cordata in Treating Pneumonia Caused by SARS-CoV-2 ENSG00000169047 ENSG00000198793 ENSG00000143839 ENSG00000112715 ENSG00000146648 PMC7875638__F4 Network with 11 herbs, 165 active ingredients, 110 intersection targets, and 8 signaling pathways ENSG00000087245 ENSG00000100084 ENSG00000172680 PMC4496101__F1 The extrinsic and intrinsic apoptotic pathway ENSG00000168040 ENSG00000115317 PMC4148637__F1 Relationship between PI3-K–Akt–mTOR signaling and autophagy in muscular dystrophy ENSG00000145782 PMC4697333__F5 Reconstruction of TNFAsignaling pathway (target instance) ENSG00000110700 ENSG00000105401 ENSG00000169047 ENSG00000170606 ENSG00000171791 ENSG00000100485 ENSG00000168256 ENSG00000035681 ENSG00000163481 ENSG00000160202 ENSG00000197885 ENSG00000133884 ENSG00000177426 ENSG00000185290 ENSG00000183735 ENSG00000138663 ENSG00000144802 ENSG00000105808 ENSG00000105640 ENSG00000138757 ENSG00000113558 ENSG00000084652 ENSG00000138032 ENSG00000117408 ENSG00000139613 ENSG00000157625 ENSG00000198933 ENSG00000110925 ENSG00000184432 ENSG00000140464 ENSG00000064012 ENSG00000280548 ENSG00000162889 ENSG00000183763 ENSG00000166167 ENSG00000170027 ENSG00000142534 ENSG00000065559 ENSG00000127666 ENSG00000163904 ENSG00000147669 ENSG00000133124 ENSG00000131323 ENSG00000175104 ENSG00000285379 ENSG00000127616 ENSG00000130726 ENSG00000168884 ENSG00000079387 ENSG00000243414 ENSG00000119401 ENSG00000050748 ENSG00000095015 ENSG00000158517 ENSG00000169032 ENSG00000137764 ENSG00000077150 ENSG00000126803 ENSG00000170266 ENSG00000166501 ENSG00000106305 ENSG00000215301 ENSG00000189067 ENSG00000168028 ENSG00000065361 ENSG00000103035 ENSG00000269335 ENSG00000023697 ENSG00000125995 ENSG00000105669 ENSG00000198901 ENSG00000185627 ENSG00000177606 ENSG00000280477 ENSG00000074266 ENSG00000028137 ENSG00000163636 ENSG00000137713 ENSG00000073584 ENSG00000110330 ENSG00000171444 ENSG00000122218 ENSG00000108443 ENSG00000112118 ENSG00000265972 ENSG00000073111 ENSG00000198300 ENSG00000166508 ENSG00000177700 ENSG00000076928 ENSG00000132382 ENSG00000167941 ENSG00000090060 ENSG00000139687 ENSG00000136108 ENSG00000113600 ENSG00000162551 ENSG00000285152 ENSG00000116717 ENSG00000134287 ENSG00000125347 ENSG00000106100 ENSG00000174444 ENSG00000068028 ENSG00000117650 ENSG00000175166 ENSG00000111653 ENSG00000198612 ENSG00000146648 ENSG00000051523 ENSG00000182481 ENSG00000104856 ENSG00000110514 ENSG00000102871 ENSG00000036672 ENSG00000198793 ENSG00000092820 ENSG00000179295 ENSG00000066117 ENSG00000102226 ENSG00000078747 ENSG00000263528 ENSG00000100504 ENSG00000104365 ENSG00000005339 ENSG00000033800 ENSG00000173039 ENSG00000162924 ENSG00000168040 ENSG00000072803 ENSG00000185104 ENSG00000278268 ENSG00000067606 ENSG00000256646 PMC10647767__F4 Developments in Genetics: Better Management of Ovarian Cancer Patients ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC4697333__F6 Cross-talks between TGFBsignaling pathway and TNFAsignaling pathway (target instance) ENSG00000029363 ENSG00000005073 ENSG00000254986 ENSG00000171791 ENSG00000162772 ENSG00000100485 ENSG00000088038 ENSG00000035681 ENSG00000136826 ENSG00000163481 ENSG00000154917 ENSG00000197885 ENSG00000175634 ENSG00000103479 ENSG00000163882 ENSG00000138663 ENSG00000144802 ENSG00000166337 ENSG00000082175 ENSG00000100142 ENSG00000117408 ENSG00000142405 ENSG00000110925 ENSG00000184432 ENSG00000176396 ENSG00000168495 ENSG00000282899 ENSG00000054523 ENSG00000145362 ENSG00000183763 ENSG00000125931 ENSG00000138795 ENSG00000104131 ENSG00000264522 ENSG00000120699 ENSG00000123091 ENSG00000125107 ENSG00000150656 ENSG00000135473 ENSG00000108590 ENSG00000152520 ENSG00000083520 ENSG00000142534 ENSG00000143164 ENSG00000179151 ENSG00000070366 ENSG00000126777 ENSG00000125351 ENSG00000168589 ENSG00000005243 ENSG00000157106 ENSG00000100442 ENSG00000205220 ENSG00000130227 ENSG00000104408 ENSG00000143125 ENSG00000107223 ENSG00000080802 ENSG00000163904 ENSG00000108179 ENSG00000164093 ENSG00000175390 ENSG00000175104 ENSG00000122779 ENSG00000108344 ENSG00000157450 ENSG00000127616 ENSG00000079387 ENSG00000243414 ENSG00000108395 ENSG00000128016 ENSG00000157933 ENSG00000291971 ENSG00000205302 ENSG00000182944 ENSG00000020633 ENSG00000124571 ENSG00000164162 ENSG00000164305 ENSG00000178573 ENSG00000126803 ENSG00000129515 ENSG00000088247 ENSG00000285199 ENSG00000203883 ENSG00000189067 ENSG00000114520 ENSG00000139719 ENSG00000168028 ENSG00000023734 ENSG00000259207 ENSG00000090863 ENSG00000065361 ENSG00000111361 ENSG00000113140 ENSG00000138411 ENSG00000197905 ENSG00000105669 ENSG00000149311 ENSG00000198901 ENSG00000185627 ENSG00000164483 ENSG00000028528 ENSG00000152804 ENSG00000127863 ENSG00000143799 ENSG00000073584 ENSG00000090061 ENSG00000094880 ENSG00000156735 ENSG00000141552 ENSG00000142178 ENSG00000122218 ENSG00000136100 ENSG00000104142 ENSG00000118707 ENSG00000112118 ENSG00000205250 ENSG00000160783 ENSG00000076003 ENSG00000172795 ENSG00000215305 ENSG00000198300 ENSG00000196628 ENSG00000168522 ENSG00000166508 ENSG00000012048 ENSG00000177700 ENSG00000134086 ENSG00000005810 ENSG00000076928 ENSG00000159216 ENSG00000144554 ENSG00000084676 ENSG00000078900 ENSG00000198742 ENSG00000136997 ENSG00000176248 ENSG00000090060 ENSG00000136108 ENSG00000109670 ENSG00000197713 ENSG00000169554 ENSG00000078399 ENSG00000134287 ENSG00000106100 ENSG00000276561 ENSG00000127334 ENSG00000139618 ENSG00000076604 ENSG00000143537 ENSG00000114126 ENSG00000118503 ENSG00000175166 ENSG00000111653 ENSG00000198612 ENSG00000051523 ENSG00000104856 ENSG00000112701 ENSG00000184221 ENSG00000105329 ENSG00000110514 ENSG00000139567 ENSG00000036672 ENSG00000130522 ENSG00000023287 ENSG00000198793 ENSG00000112242 ENSG00000103657 ENSG00000155090 ENSG00000137834 ENSG00000005339 ENSG00000183072 ENSG00000126883 ENSG00000162924 ENSG00000067900 ENSG00000083312 ENSG00000081189 ENSG00000184481 ENSG00000160691 ENSG00000162385 ENSG00000160973 ENSG00000170604 ENSG00000141480 ENSG00000057468 ENSG00000102974 ENSG00000175305 PMC10647767__F5 Developments in Genetics: Better Management of Ovarian Cancer Patients ENSG00000087245 ENSG00000170558 ENSG00000168036 ENSG00000100985 ENSG00000168610 PMC4697333__F3 Reconstruction of Notch signaling pathway (target instance) ENSG00000135547 ENSG00000065675 ENSG00000137845 ENSG00000123124 ENSG00000198681 ENSG00000135441 ENSG00000170365 ENSG00000144485 ENSG00000018236 ENSG00000143801 ENSG00000168214 ENSG00000128917 ENSG00000123933 ENSG00000196498 ENSG00000022267 ENSG00000138795 ENSG00000142192 ENSG00000148400 ENSG00000213341 ENSG00000213463 ENSG00000281766 ENSG00000063245 ENSG00000197070 ENSG00000117122 ENSG00000065526 ENSG00000121481 ENSG00000133961 ENSG00000101752 ENSG00000140564 ENSG00000291971 ENSG00000196591 ENSG00000020633 ENSG00000168036 ENSG00000105647 ENSG00000070444 ENSG00000184384 ENSG00000283780 ENSG00000078747 ENSG00000169375 ENSG00000100603 ENSG00000278693 ENSG00000100811 ENSG00000152495 ENSG00000173039 ENSG00000184916 ENSG00000168610 ENSG00000135144 ENSG00000090932 ENSG00000106003 ENSG00000139352 ENSG00000164105 ENSG00000091073 ENSG00000145604 ENSG00000071564 ENSG00000183337 ENSG00000067606 ENSG00000177606 ENSG00000048052 ENSG00000114315 ENSG00000128965 PMC5250669__F7 UPR activation in the spinal cord from an X-ALD mouse model ENSG00000128272 ENSG00000144895 ENSG00000088298 ENSG00000100219 PMC10647767__F6 Developments in Genetics: Better Management of Ovarian Cancer Patients ENSG00000019991 ENSG00000198793 ENSG00000168610 PMC4123468__F7 Reactive Oxygen and Nitrogen Species in Steatotic Hepatocytes: A Molecular Perspective on the Pathophysiology of Ischemia-Reperfusion Injury in the Fatty Liver ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC4697333__F4 Reconstruction of TGFBsignaling pathway (target instance) ENSG00000124789 ENSG00000169856 ENSG00000178999 ENSG00000122877 ENSG00000162772 ENSG00000124762 ENSG00000088038 ENSG00000177426 ENSG00000103479 ENSG00000113558 ENSG00000116030 ENSG00000176396 ENSG00000176165 ENSG00000140464 ENSG00000125931 ENSG00000138134 ENSG00000166167 ENSG00000138795 ENSG00000125107 ENSG00000135473 ENSG00000152520 ENSG00000115392 ENSG00000179151 ENSG00000168589 ENSG00000157106 ENSG00000080802 ENSG00000181191 ENSG00000166887 ENSG00000144589 ENSG00000102981 ENSG00000004897 ENSG00000175104 ENSG00000157933 ENSG00000291971 ENSG00000182944 ENSG00000020633 ENSG00000115904 ENSG00000150093 ENSG00000105647 ENSG00000169032 ENSG00000164162 ENSG00000089159 ENSG00000039319 ENSG00000178573 ENSG00000088247 ENSG00000185591 ENSG00000114520 ENSG00000023734 ENSG00000259207 ENSG00000113140 ENSG00000177606 ENSG00000028528 ENSG00000137713 ENSG00000142178 ENSG00000196628 ENSG00000168522 ENSG00000123124 ENSG00000012048 ENSG00000105325 ENSG00000159216 ENSG00000084676 ENSG00000078900 ENSG00000198742 ENSG00000136997 ENSG00000176248 ENSG00000139687 ENSG00000107404 ENSG00000136603 ENSG00000184221 ENSG00000139567 ENSG00000130522 ENSG00000198793 ENSG00000168036 ENSG00000129355 ENSG00000117707 ENSG00000153107 ENSG00000103657 ENSG00000078747 ENSG00000155090 ENSG00000100603 ENSG00000178913 ENSG00000133895 ENSG00000104365 ENSG00000005339 ENSG00000109320 ENSG00000033800 ENSG00000153201 ENSG00000126883 ENSG00000067900 ENSG00000081189 ENSG00000184481 ENSG00000160691 ENSG00000162385 ENSG00000160973 ENSG00000188191 ENSG00000170604 ENSG00000141480 ENSG00000168646 ENSG00000080839 ENSG00000102974 PMC7458397__F6 p85 roles (p110 dependent and independent) in the insulin response ENSG00000070831 ENSG00000169047 PMC10647767__F8 Developments in Genetics: Better Management of Ovarian Cancer Patients ENSG00000138798 ENSG00000198793 ENSG00000168610 PMC1774279__F1 Two major intracellular pathways cause apoptosis ENSG00000120868 ENSG00000171791 PMC9203687__F1 ILC2s in Solid Tumors: Facilitate or Inhibit? ENSG00000081041 PMC8495393__F8 FGF7-induced E11 facilitates cell-cell communication through connexin43 ENSG00000152661 ENSG00000070831 ENSG00000162493 ENSG00000140285 PMC6350546__F2 Targets and the simplified downstream effects of their autoantibodies encountered during dermatomyositis ENSG00000088888 PMC6902895__F2 The biosynthetic pathway for argyrin production in Cystobacter sp ENSG00000081181 ENSG00000118520 PMC5913620__F2 Regulation of Beta-cell autophagy ENSG00000166349 ENSG00000177169 ENSG00000111537 ENSG00000128272 ENSG00000083290 ENSG00000144895 ENSG00000125538 ENSG00000096717 ENSG00000175097 ENSG00000057663 PMC9570087__F1 Protein Acetylation Going Viral: Implications in Antiviral Immunity and Viral Infection ENSG00000094631 ENSG00000213928 ENSG00000187608 ENSG00000163565 ENSG00000169914 ENSG00000276561 ENSG00000142166 ENSG00000171720 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000048052 ENSG00000036473 ENSG00000172977 ENSG00000096717 PMC4608686__F6 Equivalent Gene Expression Profiles between Glatopa™ and Copaxone® ENSG00000197747 ENSG00000134460 ENSG00000147168 ENSG00000134982 ENSG00000183625 ENSG00000197272 ENSG00000117322 ENSG00000115607 ENSG00000150782 ENSG00000169245 ENSG00000186810 ENSG00000138378 ENSG00000111537 ENSG00000160223 ENSG00000107485 ENSG00000172936 ENSG00000113302 PMC5868363__F11 Possible cellular mechanisms involved in calycopterin-induced apoptosis in HepG2 cells ENSG00000120868 ENSG00000171791 PMC7396666__F2 Mammalian UPR ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC3742180__F8 Comparison of Cellular Uptake and Inflammatory Response via Toll-Like Receptor 4 to Lipopolysaccharide and Titanium Dioxide Nanoparticles ENSG00000170458 ENSG00000136869 PMC5843858__F4 Diagram showing the possible mechanism involved in the difference between the angiotensin-converting enzyme (ACE) I/D polymorphisms affecting the generation of kinin peptide agonists for B2R and B1R in the downstream variation signaling effects ENSG00000169047 ENSG00000198793 ENSG00000135678 PMC4446516__F1 Complement activation pathways and their regulators ENSG00000039537 ENSG00000009724 ENSG00000113600 ENSG00000291559 ENSG00000203710 ENSG00000244731 ENSG00000166278 ENSG00000117322 PMC4442886__F1 MTOR pathway and its interactions with other important pathways and cellular process relevant to cancer ENSG00000134086 ENSG00000198793 ENSG00000123374 ENSG00000146648 ENSG00000121966 PMC4714670__F4 Cooperation between RasV12 and oncogenic niche cells (ONCs) PMC3342401__F7 Summary diagram of the proposed ADM signaling pathway in retina ENSG00000148926 ENSG00000131477 PMC5563468__F5 Regulation of the ROCK/MRTF/SRF pathway in fibroblasts ENSG00000198670 PMC6941795__F2 Metabolic adaptation and maladaptation in adipose tissue ENSG00000135218 ENSG00000142611 ENSG00000156026 ENSG00000198626 PMC11048169__F1 Main signaling pathways within cancer cells ENSG00000109452 ENSG00000065361 ENSG00000095015 ENSG00000065559 ENSG00000171791 ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000177606 ENSG00000136997 ENSG00000150907 ENSG00000105810 ENSG00000146648 ENSG00000178568 PMC11048169__F3 Information exchange and signal transmission between cells within the tumor microenvironment ENSG00000081181 ENSG00000291603 ENSG00000148400 ENSG00000121807 ENSG00000127191 ENSG00000108691 ENSG00000111537 ENSG00000128272 ENSG00000213658 ENSG00000144895 ENSG00000074181 ENSG00000113520 ENSG00000100219 PMC3113807__F5 The Interplay between Protein L-Isoaspartyl Methyltransferase Activity and Insulin-Like Signaling to Extend Lifespan in Caenorhabditis elegans ENSG00000118515 ENSG00000078674 PMC3613937__F1 Desmoglein-1, differentiation, and disease ENSG00000138798 ENSG00000203782 ENSG00000112851 ENSG00000134760 ENSG00000108061 PMC8353812__F10 Characterization and comparative analysis of transcriptional profiles of porcine colostrum and mature milk at different parities ENSG00000112280 ENSG00000259207 ENSG00000005961 ENSG00000153094 ENSG00000108342 ENSG00000105647 ENSG00000105639 ENSG00000102678 ENSG00000101680 ENSG00000064300 ENSG00000188153 ENSG00000169231 ENSG00000066468 ENSG00000041982 ENSG00000049130 ENSG00000186340 ENSG00000146592 PMC10301361__F4 Involvement of the cytoskeleton in the immune response to viral infections ENSG00000183735 ENSG00000088888 PMC9666114__F1 MP0274, a Novel DARPin Therapeutic Targeting Human EGFR2 Signaling in Breast Cancer After Prior Trastuzumab and Pertuzumab ENSG00000002330 ENSG00000198793 PMC2268956__F3 The major pathways leading to apoptosis ENSG00000120868 ENSG00000115317 PMC4340657__F1 Modes of cell death ENSG00000162711 ENSG00000168040 ENSG00000168404 PMC9166799__F5 Secreted ARSs function in cancer ENSG00000163464 ENSG00000113361 ENSG00000106105 ENSG00000113407 ENSG00000065427 ENSG00000026103 PMC3977891__F2 Interplay between Wnt signaling and other anti-ageing pathways ENSG00000134982 ENSG00000198793 ENSG00000110931 ENSG00000096717 PMC7649144__F1 DHEA is synthesized from pregnenolone through the Δ5pathway (red arrows) thanks the activity of the enzyme CYP17A1 ENSG00000203859 PMC5141431__F4 Replicatively senescent human fibroblasts reveal a distinct intracellular metabolic profile with alterations in NAD+ and nicotinamide metabolism ENSG00000105835 ENSG00000123572 PMC9208818__F3 Current Status, Opportunities, and Challenges of Exosomes in Oral Cancer Diagnosis and Treatment ENSG00000091317 ENSG00000137033 ENSG00000138798 ENSG00000146648 ENSG00000137801 PMC3189824__F2 Schematic model for the activation of NFKB signaling pathways ENSG00000104856 ENSG00000162924 ENSG00000111321 ENSG00000150787 PMC7877337__F3 Virulence factors and related effects in P ENSG00000125538 PMC7471374__F2 Upstream and downstream pathways of CARD9 ENSG00000187796 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC4549066__F1 Activation signals for effector and regulatory T-cell division and proliferation ENSG00000198793 ENSG00000049768 ENSG00000105639 ENSG00000292210 PMC8146599__F3 Centrosome Dynamics and Its Role in Inflammatory Response and Metastatic Process ENSG00000167772 ENSG00000130513 PMC7973041__F6 m6A methylation plays a critical role in adaptive immunity ENSG00000134086 ENSG00000149658 ENSG00000198492 ENSG00000165819 PMC7399146__F3 Autophageal mechanism and stages ENSG00000177169 ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC7399146__F4 Physical exercise actions against aging brain and the apoptotic process ENSG00000120868 ENSG00000168040 ENSG00000026103 PMC9604507__F1 Reversible Platelet Integrin AIIbB3 Activation and Thrombus Instability ENSG00000110799 ENSG00000145321 ENSG00000010671 PMC7565641__F5 Innate immune signaling pathways modulating BV transgene expression ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000276561 PMC6896028__F1 Nrf2, through its targeted genes, has an anti-carcinogenic role in the case of normal cells and a pro-carcinogenic effect in the case of transformed malignant cells ENSG00000128272 ENSG00000117118 ENSG00000169429 ENSG00000135069 ENSG00000100985 ENSG00000112715 ENSG00000106853 ENSG00000118777 ENSG00000023909 ENSG00000170779 ENSG00000186832 ENSG00000079999 PMC5515859__F8 Proposed metabolic pathway of F18 in vitro ENSG00000131781 PMC5651170__F2 Adaptive Immunity Dysregulation in Acute Coronary Syndromes: From Cellular and Molecular Basis to Clinical Implications ENSG00000291603 ENSG00000134982 PMC6896028__F2 The Nrf2 pathway is regulated at multiple levels by different microRNAs ENSG00000100387 ENSG00000079999 PMC7973041__F3 m6A modification participates in innate immunity via regulating the recognitions of unmodified transcribed RNA (tRNA), invading pathogens, exogenous RNAs, and aberrant endogenous double-stranded RNA (dsRNA) ENSG00000088888 ENSG00000144895 ENSG00000135828 ENSG00000164342 PMC7129915__F1 Summary of antiviral signaling pathways in chickens ENSG00000213928 ENSG00000088888 ENSG00000136869 ENSG00000150455 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC9478308__F6 Research into the mechanism of intervention of SanQi in endometriosis based on network pharmacology and molecular docking technology ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000002330 ENSG00000069482 ENSG00000186716 ENSG00000136997 ENSG00000104894 PMC9627214__F2 Necroptosis: A new target for prevention of osteoporosis ENSG00000137275 ENSG00000102871 ENSG00000125538 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC8263639__F6 Tipping-point for apoptosis following dual inhibition of HER2 signaling network by T-DM1 plus GDC-0980 maximizes anti-tumor efficacy ENSG00000002330 ENSG00000164327 ENSG00000171791 PMC7471374__F3 Maturation of DCs and IL-1A/B mediated by CARD9 ENSG00000162711 ENSG00000115594 PMC5962685__F8 ALA metabolic pathway of cucumber under NaCl stress ENSG00000015285 ENSG00000127948 PMC5002062__F1 ClC-Kb/2 expression and function in the distal nephron ENSG00000126562 ENSG00000088836 ENSG00000060237 PMC4580658__F1 Schematic diagram showing select signaling pathways in melanoma ENSG00000135446 ENSG00000136997 PMC7237829__F1 Endoplasmic Reticulum Stress Signaling in Cancer Cells ENSG00000100220 ENSG00000128272 ENSG00000144895 PMC8258675__F1 Mechanisms associated with the depigmentation of brown eggshells: a review ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000188690 ENSG00000115657 ENSG00000118777 PMC7576986__F2 Type I IFN signaling and viral countermeasures ENSG00000213928 ENSG00000105397 ENSG00000115415 PMC6008657__F3 Insulin signaling also controls mTOR pathway that inhibits autophagy ENSG00000177169 ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC26952__F7 Activation of specific target genes by TGFB and Wnt pathways ENSG00000138795 PMC6387036__F2 HBV- and HCC-related genes in L1 biology ENSG00000164362 ENSG00000168036 ENSG00000164754 PMC9425222__F3 DNA Repair Pathway Genes Associated With Ataxia ENSG00000143799 ENSG00000039650 ENSG00000291803 ENSG00000163918 ENSG00000035928 ENSG00000139618 ENSG00000149311 ENSG00000012048 ENSG00000105486 ENSG00000132646 ENSG00000137074 ENSG00000051180 ENSG00000133119 ENSG00000042088 PMC2504760__F1 Mechanisms by which diabetes increases cardiovascular disease ENSG00000135218 ENSG00000162692 PMC2831538__F3 Autophagy regulation in response to stress ENSG00000144895 ENSG00000198793 ENSG00000145782 PMC10137494__F2 Steroid synthesis pathway ENSG00000179142 PMC338270__F1 Modification pathway of proteins for isoprenylation/methylation and effects of inhibitors of each enzymatic step ENSG00000116237 PMC7472700__F3 T-MPs function ENSG00000164430 PMC11882765__F1 Ferroptosis Signalling Pathway ENSG00000228716 ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000115107 PMC7563796__F1 Multiple functions of microglia and macrophages in brain injury ENSG00000108691 ENSG00000091972 ENSG00000140545 PMC7472700__F1 CGAS–STING pathway ENSG00000104856 ENSG00000213928 ENSG00000164430 ENSG00000175104 PMC7299722__F1 Effects of doxorubicin on cardiac mitochondrial dynamics and mitochondrial function ENSG00000116688 ENSG00000214253 PMC2816010__F6 Effect of dasatinib on the BCR-ABL signaling pathway ENSG00000029363 ENSG00000033327 ENSG00000110395 ENSG00000291971 ENSG00000186716 ENSG00000136997 ENSG00000171791 ENSG00000150787 ENSG00000081189 PMC10671302__F4 Roles and Future Perspectives of Chitinase 3-like 1 in Macrophage Polarization and the Development of Diseases ENSG00000133048 ENSG00000026508 ENSG00000112715 PMC9357805__F2 Microenvironment That Regulates Vascular Wall Stem/Progenitor Cells in Vascular Injury and Repair ENSG00000070831 ENSG00000160293 ENSG00000121807 ENSG00000168610 PMC3500853__F3 EphrinB reverse signaling ENSG00000070831 ENSG00000149269 ENSG00000163914 PMC6177397__F2 RDGN regulates TGFB signaling transduction in tumor cells.Notes: TGFB binds to TBR and activates SARA, which then recruits and activates intracellular SMAD2/3 protein ENSG00000276644 ENSG00000126778 PMC5810846__F4 Small-molecule inhibitors of Wnt signaling pathway: towards novel anticancer therapeutics ENSG00000061938 PMC7260844__F1 Schematic representation the regulatory networks of lncRNAs in major biology activities during brain developmental process ENSG00000169554 ENSG00000147862 ENSG00000168036 ENSG00000205927 ENSG00000114315 ENSG00000178691 PMC8505078__F6 Exploring the Mechanism of Resveratrol in Reducing the Soft Tissue Damage of Osteoarthritis Based on Network Pharmacology and Experimental Pharmacology ENSG00000142192 ENSG00000226275 ENSG00000170458 ENSG00000111837 ENSG00000184500 PMC2634670__F1 Strategies to inhibit the VEGF signalling pathway ENSG00000128917 PMC2577427__F9 Model depicting signaling pathways for TPR-mediated modulation of OLG development and function ENSG00000047410 ENSG00000163914 PMC5809441__F1 Pleiotropic effects of statins ENSG00000132693 PMC11274344__F6 The cancer antioxidant regulation system in therapeutic resistance and scientific questions to be solved ENSG00000151376 ENSG00000065911 ENSG00000284774 ENSG00000151012 ENSG00000152620 ENSG00000112992 ENSG00000023909 ENSG00000079999 ENSG00000065833 ENSG00000100714 ENSG00000082212 ENSG00000115419 ENSG00000196517 PMC7167007__F1 Interferon signaling pathway ENSG00000183735 ENSG00000213928 ENSG00000105397 ENSG00000136869 ENSG00000142166 PMC5385290__F2 Folate Nutrition and Blood-Brain Barrier Dysfunction ENSG00000228716 ENSG00000116984 PMC10937114__F3 Hypoxia affects adenosine signaling pathways in erythrocytes(A) AMPK-BPGM signaling pathway ENSG00000170425 ENSG00000133805 PMC8307963__F2 Syndromes of Thrombotic Microangiopathy: A Critical Appraisal on Complement Dysregulation ENSG00000113600 ENSG00000117335 ENSG00000236625 PMC8005659__F1 Protective effects of sirtuin 3 on titanium particle-induced osteogenic inhibition by regulating the NLRP3 inflammasome via the GSK-3B/Beta-catenin signalling pathway ENSG00000278718 ENSG00000162711 ENSG00000281324 ENSG00000162337 ENSG00000125538 ENSG00000168036 ENSG00000142082 ENSG00000168646 PMC8139204__F2 CD36 Signaling in Diabetic Cardiomyopathy ENSG00000135218 ENSG00000169047 ENSG00000220205 PMC4205853__F2 Schematic comparing signaling cascades activated by EPO in microglia and macrophages ENSG00000198793 ENSG00000168036 PMC8120550__F8 Overexpression of ING3 is associated with attenuation of migration and invasion in breast cancer ENSG00000173039 ENSG00000162924 ENSG00000128602 PMC6412134__F1 Targeting GBM CSC-mediated chemo/radio resistance by small molecule inhibitors ENSG00000149311 ENSG00000276618 ENSG00000168036 ENSG00000164690 ENSG00000128602 ENSG00000137845 ENSG00000118777 ENSG00000146648 ENSG00000198910 PMC5842951__F1 Rho kinase signaling and cardiac physiology ENSG00000134775 ENSG00000067900 PMC5810846__F1 Small-molecule inhibitors of Wnt signaling pathway: towards novel anticancer therapeutics ENSG00000138795 ENSG00000281324 ENSG00000134982 ENSG00000168036 PMC5694448__F6 A model of leptospire-induced apoptosis in macrophages through bid-induced release of AIF/ Endog signaling pathway ENSG00000064012 PMC6048953__F2 Insulin action and resistance in obesity and type 2 diabetes ENSG00000150907 PMC5810846__F3 Small-molecule inhibitors of Wnt signaling pathway: towards novel anticancer therapeutics ENSG00000180245 PMC9685520__F1 Phase separation drives the formation of biomolecular condensates in the immune system ENSG00000183735 ENSG00000164430 PMC2100342__F3 Activation of NFKB via the classical and the alternative pathway ENSG00000104856 ENSG00000173039 ENSG00000162924 ENSG00000111321 ENSG00000162692 PMC4813427__F6 Summary of NOP receptor signaling ENSG00000120500 PMC3437536__F1 Class I phosphoinositide-3-kinase (PI3K) signaling pathway ENSG00000002330 ENSG00000150907 PMC5578103__F3 Schematic diagram illustrating the mechanisms of how the estrogen receptor (ER) coordinates with the epidermal growth factor receptor (EGFR) to affect the cell growth in the lung adenocarcinoma ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8544609__F2 Hormetic ER stress signaling elucidated in HSCs ENSG00000175938 ENSG00000128272 ENSG00000159216 ENSG00000198171 ENSG00000167323 ENSG00000293604 ENSG00000166278 ENSG00000100219 ENSG00000109689 PMC2266095__F2 Schematic presentation of the NFKB signaling network in radiation-induced adaptive radioresistance ENSG00000149311 ENSG00000099860 ENSG00000138385 PMC11941885__F3 Mechanical stress-related podocyte injury ENSG00000115109 ENSG00000070831 ENSG00000137672 ENSG00000072315 ENSG00000175505 PMC2872497__F4 Epigenetically reprogramming metastatic tumor cells with an embryonic microenvironment ENSG00000156574 PMC11941885__F2 Immune-mediated podocyte injury ENSG00000196352 ENSG00000172936 ENSG00000150455 ENSG00000276561 PMC8664902__F5 Epigenome association study for DNA methylation biomarkers in buccal and monocyte cells for female rheumatoid arthritis ENSG00000261832 ENSG00000184347 ENSG00000180257 ENSG00000110799 ENSG00000243156 ENSG00000144619 ENSG00000079482 ENSG00000104381 ENSG00000174885 ENSG00000020633 ENSG00000160710 ENSG00000197563 ENSG00000049618 ENSG00000047936 ENSG00000145526 ENSG00000166164 ENSG00000285176 ENSG00000041982 ENSG00000171735 ENSG00000108557 ENSG00000226492 ENSG00000152208 ENSG00000105246 ENSG00000276996 ENSG00000253729 ENSG00000282899 ENSG00000101901 ENSG00000087245 ENSG00000005339 ENSG00000152495 ENSG00000109321 ENSG00000173039 ENSG00000285250 ENSG00000127191 ENSG00000138160 ENSG00000007171 ENSG00000104723 ENSG00000189283 ENSG00000159921 ENSG00000138378 ENSG00000150672 ENSG00000067606 ENSG00000103769 ENSG00000185339 ENSG00000083799 ENSG00000119715 ENSG00000113448 ENSG00000127616 PMC8664902__F6 Epigenome association study for DNA methylation biomarkers in buccal and monocyte cells for female rheumatoid arthritis ENSG00000049323 ENSG00000140564 ENSG00000184156 ENSG00000142798 ENSG00000184347 ENSG00000147789 ENSG00000109906 ENSG00000170558 ENSG00000174885 ENSG00000171791 ENSG00000150455 ENSG00000158747 ENSG00000099822 ENSG00000213853 ENSG00000099991 ENSG00000165457 ENSG00000143740 ENSG00000119655 ENSG00000150907 ENSG00000088247 ENSG00000291918 ENSG00000188612 ENSG00000131473 ENSG00000148400 ENSG00000081913 ENSG00000167468 ENSG00000163131 ENSG00000163794 ENSG00000171848 ENSG00000112149 ENSG00000105426 ENSG00000096717 ENSG00000038945 ENSG00000131196 ENSG00000156113 ENSG00000124783 PMC6263010__F1 Sonic hedgehog signaling controls dentate gyrus patterning and adult neurogenesis in the hippocampus ENSG00000077279 ENSG00000131095 PMC10778012__F5 tRF-mediated translational regulation ENSG00000065978 ENSG00000184916 PMC6263010__F2 Sonic hedgehog signaling controls dentate gyrus patterning and adult neurogenesis in the hippocampus ENSG00000077279 ENSG00000131095 ENSG00000164690 PMC10778012__F1 Oncogenic signaling can drive changes in the transcription of tRNA genes ENSG00000198793 ENSG00000136997 PMC3058926__F5A Proof of Concept: A review on how network and systems biology approaches aid in the discovery of potent anticancer drug combinations ENSG00000108861 ENSG00000163220 ENSG00000158828 ENSG00000027697 ENSG00000168036 ENSG00000265972 ENSG00000099194 ENSG00000176153 ENSG00000186529 ENSG00000076864 ENSG00000196136 ENSG00000153140 ENSG00000288411 ENSG00000145623 ENSG00000134324 ENSG00000172915 PMC7260686__F5 Herb-target-signaling pathway interaction network ENSG00000117020 ENSG00000110395 ENSG00000186716 ENSG00000136997 ENSG00000164362 ENSG00000112715 ENSG00000277641 ENSG00000146648 ENSG00000155760 ENSG00000139687 ENSG00000150630 PMC2628394__F15 Biological network representing the schizophrenia p-value ranking ENSG00000170370 ENSG00000125398 ENSG00000119508 ENSG00000118777 PMC3931732__F9 CHC-1 and EPN-1 promote actin polymerization in response to CED-1 signaling ENSG00000063245 ENSG00000157890 ENSG00000145794 PMC2628394__F16 Biological network representing the bipolar disorder p-value ranking ENSG00000019582 ENSG00000128272 ENSG00000112964 ENSG00000130522 ENSG00000139515 ENSG00000146457 ENSG00000123268 ENSG00000095794 PMC9232097__F7 Integrating Network Pharmacology and Experimental Verification to Explore the Pharmacological Mechanisms of Aloin Against Gastric Cancer ENSG00000140992 ENSG00000157404 ENSG00000142627 ENSG00000291971 ENSG00000101266 ENSG00000145386 ENSG00000105639 ENSG00000166851 ENSG00000073756 ENSG00000196396 ENSG00000164305 ENSG00000007171 ENSG00000132170 ENSG00000143387 ENSG00000082175 ENSG00000128052 ENSG00000123374 ENSG00000077782 ENSG00000146648 ENSG00000140443 PMC5912970__F2 Genes affecting progression of bacteriophage P22 infection in Salmonella identified by transposon and single gene deletion screens ENSG00000069482 PMC6492940__F4 Essential metabolites ENSG00000105227 PMC6492940__F5 Inflammation, apoptosis and cell survival ENSG00000168036 ENSG00000120868 PMC3325001__F2 Modes of Hh pathway signaling ENSG00000128602 PMC9314556__F1 Mitochondrial Epigenetics Regulating Inflammation in Cancer and Aging ENSG00000183735 ENSG00000164430 PMC3325001__F1 Hh signaling pathway ENSG00000128602 PMC7755476__F11 Cell cycle and (b) TGF-beta-signaling pathway regulated by the E2F alteration in brain and CNS cancer ENSG00000108055 ENSG00000134982 ENSG00000156574 ENSG00000134363 ENSG00000091651 ENSG00000277273 ENSG00000145604 ENSG00000182175 ENSG00000111537 ENSG00000131043 ENSG00000095739 ENSG00000135446 ENSG00000132646 ENSG00000115942 ENSG00000123374 ENSG00000164754 ENSG00000164093 PMC7576986__F1 IFN-I induction and viral counteracting actions ENSG00000183735 ENSG00000239732 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC4380423__F5 Specific Medicinal Plant Polysaccharides Effectively Enhance the Potency of a DC-Based Vaccine against Mouse Mammary Tumor Metastasis ENSG00000108702 ENSG00000125538 ENSG00000108342 ENSG00000184371 ENSG00000164400 ENSG00000104432 ENSG00000113525 PMC11092636__F3 Exercise activates the EGFR/insulin signaling ENSG00000104812 ENSG00000142192 ENSG00000171105 ENSG00000198793 ENSG00000136111 ENSG00000136854 ENSG00000065559 ENSG00000169032 ENSG00000139625 ENSG00000006062 ENSG00000132639 ENSG00000137764 ENSG00000179295 ENSG00000164879 ENSG00000107263 ENSG00000148082 ENSG00000067606 PMC4437334__F1 Active killing of motoneurons through death receptors under pathological context ENSG00000159128 ENSG00000111537 ENSG00000027697 ENSG00000111321 ENSG00000168040 ENSG00000026103 PMC5663622__F3 Moving forward with actionable therapeutic targets and opportunities in endometrial cancer: NCI clinical trials planning meeting report on identifying key genes and molecular pathways for targeted endometrial cancer trials ENSG00000180210 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC5038604__F4 Protein-protein interaction network of the overlapped DEGs ENSG00000170266 ENSG00000072110 ENSG00000001626 ENSG00000173702 PMC5595906__F4 Results of PPI network analyis ENSG00000100519 ENSG00000160075 ENSG00000001167 ENSG00000050748 ENSG00000172046 ENSG00000276644 ENSG00000095015 ENSG00000113161 ENSG00000119969 ENSG00000151929 ENSG00000162772 ENSG00000166851 ENSG00000159788 ENSG00000135457 ENSG00000106571 ENSG00000109911 ENSG00000180992 ENSG00000008196 ENSG00000125445 ENSG00000028839 ENSG00000116750 ENSG00000164167 ENSG00000084463 ENSG00000100811 ENSG00000277707 ENSG00000023516 ENSG00000167118 ENSG00000103035 ENSG00000173933 ENSG00000162551 ENSG00000276463 ENSG00000198242 ENSG00000077279 ENSG00000117360 ENSG00000092199 ENSG00000147274 ENSG00000183337 ENSG00000198176 ENSG00000135446 ENSG00000132646 ENSG00000133112 ENSG00000187244 ENSG00000127616 ENSG00000184205 ENSG00000087274 PMC4486731__F3A BRAF gene: From human cancers to developmental syndromes ENSG00000135446 PMC2781329__F4 Schematic diagram for HO-1 modulation of signaling pathway and adiponectin, EET levels, and vascular function ENSG00000159346 ENSG00000285070 PMC3218540__F2 Folate metabolic pathway ENSG00000228716 PMC4421076__F6 Sustained Interleukin-1B Exposure Modulates Multiple Steps in Glucocorticoid Receptor Signaling, Promoting Split-Resistance to the Transactivation of Prominent Anti-Inflammatory Genes by Glucocorticoids ENSG00000008710 ENSG00000140968 ENSG00000125538 ENSG00000146678 ENSG00000115594 PMC5004238__F4 Schematic illustration of axon-microglia interactions and the CASP6/p38/TNFA signaling pathway in the spinal cord dorsal horn of male rodents ENSG00000138794 ENSG00000196689 PMC6640082__F1 Mammalian Heme Synthesis Pathway ENSG00000066926 ENSG00000126088 ENSG00000158578 ENSG00000256269 ENSG00000188690 PMC6640082__F2 Heme Synthesis Metabolon ENSG00000066926 ENSG00000126088 ENSG00000158578 ENSG00000256269 ENSG00000188690 ENSG00000284936 PMC7464452__F2 Possible endothelial–mesenchymal and epithelial–mesenchymal interactions in BPD-PH ENSG00000066468 ENSG00000070193 ENSG00000164690 ENSG00000077782 PMC4029965__F7 Predicting Response to Preoperative Chemotherapy Agents by Identifying Drug Action on Modeled MicroRNA Regulation Networks ENSG00000101109 ENSG00000082175 ENSG00000156970 ENSG00000178999 ENSG00000148154 ENSG00000102543 ENSG00000112742 PMC8539587__F1 Undercover Agents of Infection: The Stealth Strategies of T4SS-Equipped Bacterial Pathogens ENSG00000162711 ENSG00000187554 ENSG00000163568 ENSG00000125538 ENSG00000172936 ENSG00000175104 PMC7305518__F5 Graphene induced activation of macrophage signaling pathway (Zhou et al ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC4316204__F2 Remodelling the extracellular matrix in development and disease ENSG00000087245 ENSG00000157227 ENSG00000100985 PMC4316204__F3 Remodelling the extracellular matrix in development and disease ENSG00000066468 ENSG00000070193 ENSG00000087245 ENSG00000162337 ENSG00000149968 ENSG00000157227 ENSG00000277222 PMC3375273__F6 TRAF-6 Dependent Signaling Pathway Is Essential for TNF-Related Apoptosis-Inducing Ligand (TRAIL) Induces Osteoclast Differentiation ENSG00000168040 ENSG00000175104 ENSG00000131196 PMC9219669__F2 Apoptosis and (in) Pain—Potential Clinical Implications ENSG00000132906 ENSG00000171791 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC11012756__F5 Therapeutic Advances and Challenges for the Management of HPV-Associated Oropharyngeal Cancer ENSG00000083857 ENSG00000127445 ENSG00000157764 ENSG00000135446 ENSG00000198793 ENSG00000168036 ENSG00000087586 ENSG00000166851 ENSG00000109670 PMC9454904__F2 Current Understanding of Asthma Pathogenesis and Biomarkers ENSG00000163739 ENSG00000169429 PMC8371935__F1 Phylogenetic Analysis of Core Melanin Synthesis Genes Provides Novel Insights Into the Molecular Basis of Albinism in Fish ENSG00000185664 ENSG00000107165 PMC8549349__F7 ZIP10 drives osteosarcoma proliferation and chemoresistance through ITGA10-mediated activation of the PI3K/AKT pathway ENSG00000150093 ENSG00000137076 PMC6322652__F1 mTORC1 and mTORC2 as regulators of cell metabolism in immunity ENSG00000140992 ENSG00000118515 PMC2755611__F1 Regulation of aging: does autophagy underlie longevity? ENSG00000096717 ENSG00000283100 ENSG00000106459 PMC5686720__F11 Work model for NLRX1-mediated MAVS degradation during viral infection ENSG00000183735 ENSG00000088888 ENSG00000160703 PMC22672__F8 Orb6 kinase is proposed to be part of a regulatory cascade contributing to the mitotic control and responding to the Ras1 and Cdc42-dependent morphological control pathway via the Pak1/Shk1 kinase ENSG00000070831 ENSG00000149269 PMC4646251__F12 The signaling pathways involved in GnRH-induced ERK activation (red arrows) and ErbB4 cleavage (blue arrows) ENSG00000008710 ENSG00000291971 ENSG00000113070 ENSG00000010810 ENSG00000146648 ENSG00000178568 PMC5555103__F1 Fatty liver diseases are initiated by aberrant hepatic lipid metabolism, and sirtuin 1 (SIRT1) activation plays beneficial effect against the process through inhibiting de novo lipogenesis and increasing fatty acid Beta-oxidation ENSG00000042832 ENSG00000170522 ENSG00000096717 ENSG00000026103 PMC8639500__F4 SSTP1, a Host Defense Peptide, Exploits the Immunomodulatory IL6 Pathway to Induce Apoptosis in Cancer Cells ENSG00000110944 ENSG00000125740 ENSG00000125398 ENSG00000138166 ENSG00000115415 ENSG00000291431 ENSG00000177606 ENSG00000171791 ENSG00000168610 ENSG00000162892 ENSG00000136688 ENSG00000162413 PMC12041846__F6B DEGs from GSE49028 dataset of binge ethanol-treated mice on signaling pathways related to anxiety and locomotor activity ENSG00000231247 ENSG00000105664 ENSG00000005339 ENSG00000152495 ENSG00000130643 ENSG00000123268 ENSG00000087460 ENSG00000095794 ENSG00000177425 PMC12041846__F6C DEGs from GSE49028 dataset of binge ethanol-treated mice on signaling pathways related to anxiety and locomotor activity ENSG00000133019 ENSG00000180720 ENSG00000123700 ENSG00000116044 ENSG00000010810 ENSG00000087085 ENSG00000171791 ENSG00000274542 ENSG00000064300 ENSG00000007171 ENSG00000079999 ENSG00000187714 PMC12041846__F6A DEGs from GSE49028 dataset of binge ethanol-treated mice on signaling pathways related to anxiety and locomotor activity ENSG00000160145 ENSG00000291971 ENSG00000197442 ENSG00000198626 ENSG00000088256 ENSG00000135914 ENSG00000164305 ENSG00000120063 ENSG00000149968 ENSG00000173599 ENSG00000177606 ENSG00000150907 ENSG00000026508 PMC11594113__F1 Insulin-like growth factor 1 signaling pathway ENSG00000002330 ENSG00000198793 PMC3076503__F4 Bioenergenesis neurotransmitter pathways with differentially expressed genes between frontal cortex and hippocampus ENSG00000137806 ENSG00000169021 ENSG00000112695 ENSG00000171953 ENSG00000130414 ENSG00000172955 ENSG00000117118 ENSG00000027001 ENSG00000100577 ENSG00000105953 ENSG00000143252 ENSG00000182902 ENSG00000189043 ENSG00000172482 ENSG00000138777 ENSG00000164398 ENSG00000159399 ENSG00000123983 ENSG00000062485 PMC5764254__F7 Trans10,cis12 conjugated linoleic acid inhibits proliferation and migration of ovarian cancer cells by inducing ER stress, autophagy, and modulation of Src ENSG00000128272 ENSG00000291971 ENSG00000168036 PMC5413074__F6 Canonical (NFKB1) pathway requires the NEMO (NFKB essential modulator) complex (IKB kinase A, IKB kinase B, IKB kinase G) to phosphorylate IKB, leading to its degradation ENSG00000137077 PMC3076503__F5 Bioenergenesis neurotransmitter pathways with differentially expressed genes between frontal cortex and hypothalamus ENSG00000169021 ENSG00000135423 ENSG00000171953 ENSG00000130414 ENSG00000172955 ENSG00000138495 ENSG00000100577 ENSG00000127884 ENSG00000182902 ENSG00000172482 ENSG00000138777 ENSG00000113790 ENSG00000159399 ENSG00000062485 ENSG00000167701 PMC7495669__F5 Gene-vocalization links ENSG00000139287 ENSG00000112246 ENSG00000173376 ENSG00000108961 ENSG00000084463 ENSG00000111196 ENSG00000075213 PMC6003316__F5 Genes of gossypol pathway enzymes and their expressions ENSG00000110921 ENSG00000197429 PMC6355689__F3 Pathway representation for dopamine metabolism ENSG00000184845 ENSG00000169676 ENSG00000165646 ENSG00000276996 ENSG00000149295 PMC5409508__F2 Material Cues as Potent Regulators of Epigenetics and Stem Cell Function ENSG00000198793 ENSG00000163914 PMC4440595__F2 The BMP/SMAD signaling pathway ENSG00000170365 ENSG00000125968 PMC10987721__F2 Akkermansia muciniphila: a potential candidate for ameliorating metabolic diseases ENSG00000042832 ENSG00000136869 PMC3754249__F2 HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations ENSG00000131473 ENSG00000100412 ENSG00000172005 PMC3754249__F3 HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations PMC6685213__F4 Kaposi Sarcoma ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC7716495__F1 Activated and inhibited Wnt/Beta-catenin pathway ENSG00000134982 ENSG00000168036 PMC8200981__F1 Neutrophil Extracellular Traps in Tumor Metastasis: Pathological Functions and Clinical Applications ENSG00000239732 ENSG00000109861 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000100985 ENSG00000005381 PMC7716495__F2 Hallmarks of diverse categories of Wnt/Beta-catenin targeted agents in cancer ENSG00000162337 ENSG00000102312 PMC7716495__F3 Graphic overview of Wnt/Beta-catenin signaling pathway targeted interventions in cancer studies ENSG00000102312 ENSG00000168036 ENSG00000166278 PMC8061201__F2 Function of LncRNAs in diabetes-related renal inflammation and fibrosis ENSG00000162711 ENSG00000168036 PMC8848980__F6 Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus ENSG00000138795 ENSG00000117425 ENSG00000109101 ENSG00000138759 ENSG00000139648 ENSG00000141968 ENSG00000150893 ENSG00000010671 ENSG00000169231 ENSG00000178919 ENSG00000123364 ENSG00000164946 ENSG00000102245 ENSG00000185269 ENSG00000108821 ENSG00000064195 PMC8848980__F3 Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus ENSG00000019991 ENSG00000168329 ENSG00000189056 ENSG00000007908 ENSG00000158517 ENSG00000154016 ENSG00000196739 ENSG00000064300 ENSG00000010671 ENSG00000276068 ENSG00000095585 ENSG00000136457 ENSG00000169220 ENSG00000213658 ENSG00000095739 ENSG00000166501 ENSG00000015285 ENSG00000292357 ENSG00000001626 ENSG00000037280 ENSG00000171608 ENSG00000155629 PMC6679375__F3 Wnt-EarlyEx tumors show expression of Wnt-associated pathway signatures ENSG00000112576 ENSG00000178585 ENSG00000281324 ENSG00000181274 ENSG00000162337 ENSG00000134982 ENSG00000157240 ENSG00000143801 ENSG00000163251 ENSG00000147869 ENSG00000167941 ENSG00000183943 ENSG00000155011 ENSG00000136997 ENSG00000177283 ENSG00000155760 ENSG00000168772 ENSG00000087095 ENSG00000138795 ENSG00000107404 ENSG00000156076 ENSG00000292149 ENSG00000276920 ENSG00000100888 ENSG00000140807 ENSG00000163904 ENSG00000164736 ENSG00000102312 ENSG00000175792 ENSG00000004975 ENSG00000291971 ENSG00000175592 ENSG00000168036 ENSG00000104332 ENSG00000118971 ENSG00000095739 ENSG00000120057 ENSG00000104371 ENSG00000137673 ENSG00000005339 ENSG00000174804 ENSG00000165059 ENSG00000106483 ENSG00000175029 ENSG00000180138 ENSG00000070770 ENSG00000115266 ENSG00000104290 ENSG00000161202 ENSG00000168646 PMC6913804__F1 Schematic overview of cell death pathways affected by Coxiella burnetii effector proteins ENSG00000002330 PMC10741569__F1 Viruses modulate the EGFR signaling network ENSG00000132541 ENSG00000128564 ENSG00000146648 PMC3323522__F7 A Novel 3-Hydroxysteroid Dehydrogenase That Regulates Reproductive Development and Longevity ENSG00000167910 ENSG00000099377 ENSG00000135929 PMC11544528__F5 Mechanisms by which NR4A1 regulates osteoporosis and adipogenesis via the Notch signaling pathway ENSG00000114315 PMC3877685__F2 Automatic Context-Specific Subnetwork Discovery from Large Interaction Networks ENSG00000157764 ENSG00000168036 ENSG00000166278 PMC4123127__F1 Hippo in the Path to Heart Repair ENSG00000150457 ENSG00000131023 PMC8618018__F2 Morphophysiological and Proteomic Responses on Plants of Irradiation with Electromagnetic Waves ENSG00000173599 ENSG00000161513 ENSG00000167986 PMC3529568__F1 TGFB latency, activation and signal transduction ENSG00000140564 PMC8275829__F2 ADAMTS Proteases ENSG00000154736 ENSG00000140564 ENSG00000138316 ENSG00000151388 ENSG00000281244 ENSG00000145808 ENSG00000136378 ENSG00000173157 ENSG00000145536 ENSG00000140470 ENSG00000166106 ENSG00000163638 ENSG00000087116 PMC2758485__F1 Wnt/PCP signaling and its effects on organogenesis ENSG00000140463 ENSG00000168036 PMC2834542__F5 Actin cytoskeleton signaling pathway as represented by Ingenuity Pathway Analysis ENSG00000175054 PMC3901886__F1 Schematic representation of ligand-activated AHR signaling ENSG00000106546 PMC7053300__F5 MiR-17 family miRNAs are predicted to target the p21/CDK/E2F1 pathway to modulate the G1/S transition of the cell cycle under oxidative stress ENSG00000103479 ENSG00000135446 ENSG00000105810 ENSG00000118971 ENSG00000139687 ENSG00000080839 PMC9647060__F4 Transcriptome and metabolome analyses provide insights into the relevance of pericarp thickness variations in Camellia drupifera and Camellia oleifera ENSG00000084774 ENSG00000116747 PMC2864141__F1 Models of checkpoint control in (a) S ENSG00000276618 ENSG00000163624 ENSG00000113456 ENSG00000148204 ENSG00000177084 PMC7040013__F4 Pathway analysis reveals predicted gene targets enriched in predominately nervous system signaling pathways for focal (A) or diffuse (B) injury cohorts ENSG00000005339 ENSG00000144118 ENSG00000115904 ENSG00000100485 ENSG00000126458 PMC4075091__F5 Domain structure of p62 and its interacting partners ENSG00000188554 ENSG00000175104 ENSG00000079999 PMC8185227__F3 LncRNAs in the Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma ENSG00000281324 ENSG00000132382 ENSG00000198793 ENSG00000168487 ENSG00000168036 ENSG00000132964 ENSG00000168610 ENSG00000164916 PMC12221920__F3 Hippo/YAP signaling pathway in colorectal cancer: regulatory mechanisms and potential drug exploration ENSG00000129474 ENSG00000129038 ENSG00000107186 ENSG00000150457 ENSG00000131023 PMC12221920__F4 Hippo/YAP signaling pathway in colorectal cancer: regulatory mechanisms and potential drug exploration ENSG00000077454 ENSG00000284774 ENSG00000156299 ENSG00000291971 ENSG00000198793 ENSG00000050165 ENSG00000131023 ENSG00000291442 PMC12221920__F1 Two states of the Hippo pathway in the mammalian tumor microenvironment ENSG00000131023 ENSG00000291442 PMC5036969__F3 Mitochondria and Cancer ENSG00000100811 ENSG00000198793 PMC10374481__F7 HAMLET effect on cell death and mitochondrial respiration in colorectal cancer cell lines with KRAS/BRAF mutations ENSG00000023445 ENSG00000120868 ENSG00000146648 PMC2834616__F4 EGR3 and miRNAs involving in signaling pathways and regulatory networks in schizophrenia and nervous system ENSG00000198576 ENSG00000171791 ENSG00000064300 ENSG00000149295 PMC5008272__F7 Monoclonal antibody against the Wnt signaling inhibitor dickkopf-1 inhibits osteosarcoma metastasis in a preclinical model ENSG00000162337 ENSG00000134982 PMC6612409__F2 Intestinal disease-related pathway including MAPK signaling pathway, NF-kappa B signaling pathway, calcium signaling pathway, and chemokine signaling pathway ENSG00000163464 ENSG00000102871 ENSG00000291971 ENSG00000181104 ENSG00000173039 ENSG00000127191 ENSG00000073756 ENSG00000102468 ENSG00000007171 ENSG00000150782 ENSG00000170458 ENSG00000082512 ENSG00000125538 ENSG00000101188 ENSG00000166501 ENSG00000136869 ENSG00000172936 ENSG00000151617 ENSG00000175104 ENSG00000100739 ENSG00000184216 ENSG00000160951 ENSG00000062485 PMC9585326__F1 Mitochondria-associated endoplasmic reticulum membranes in insulin sensitivity, energy metabolism, and contraction of skeletal muscle ENSG00000171105 ENSG00000169047 ENSG00000136869 ENSG00000138777 PMC6878846__F1 Hereditary systemic autoinflammatory diseases and Schnitzler’s syndrome ENSG00000137275 ENSG00000102871 ENSG00000172936 ENSG00000154124 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC9024452__F6 Restricted Activation of the NFKB Pathway in Individuals with Latent Tuberculosis Infection after HIF-1A Blockade ENSG00000111012 ENSG00000150782 ENSG00000205221 PMC6977016__F3 Role and mechanisms of frequently-studied traditional herbs in treating NAFLD ENSG00000162711 ENSG00000114416 ENSG00000172936 ENSG00000096717 PMC3266662__F3 Correlations of genes in central carbon metabolism with SPPR ENSG00000159224 ENSG00000197713 ENSG00000074800 ENSG00000213658 ENSG00000122966 ENSG00000172005 ENSG00000163064 ENSG00000164778 PMC7966921__F3 Myristoylation in regulating TRIF-related adaptor molecule (TRAM) during LPS-induced TLR4 inflammatory responses ENSG00000172005 ENSG00000172936 ENSG00000136869 PMC8490662__F8 Macrophage-Mediated Bone Formation in Scaffolds Modified With MSC-Derived Extracellular Matrix Is Dependent on the Migration Inhibitory Factor Signaling Pathway ENSG00000178860 ENSG00000019582 ENSG00000099985 ENSG00000026508 PMC8968907__F4 Mitochondrial anti-apoptotic dependencies of hematologic malignancies: from disease biology to advances in precision medicine ENSG00000107562 ENSG00000026508 ENSG00000171791 ENSG00000121966 ENSG00000179295 PMC3984536__F3 HCV life cycle and points of intervention ENSG00000142627 ENSG00000130164 ENSG00000042832 ENSG00000138798 ENSG00000015520 ENSG00000285482 ENSG00000110651 ENSG00000146648 PMC6096387__F8 Proposed mechanism of JuA-mediated AB clearance ENSG00000135218 ENSG00000160179 PMC8778593__F2 Therapeutic implications of exosomes in the treatment of radiation injury ENSG00000148400 ENSG00000150457 ENSG00000175104 PMC5770815__F1 Kynurenic acid (KYNA) synthesis along the kynurenine pathway and its mode of action ENSG00000188676 ENSG00000106546 PMC5770815__F2 Kynurenic acid (KYNA)-mediated pathways of inflammatory signaling ENSG00000141480 ENSG00000291971 ENSG00000168036 ENSG00000113520 ENSG00000125347 ENSG00000106546 PMC6316386__F1 Transient receptor potential (TRP) channels and itch signaling ENSG00000133107 ENSG00000104321 ENSG00000148680 ENSG00000145777 ENSG00000198670 ENSG00000213694 ENSG00000135914 ENSG00000196689 PMC8954173__F1 Genetic Landscape of Peripheral T-Cell Lymphoma ENSG00000291603 ENSG00000213658 ENSG00000105397 ENSG00000163914 ENSG00000168036 ENSG00000113263 ENSG00000105639 ENSG00000168610 ENSG00000141968 PMC6774191__F6 ERKI/II (MAPK) can serve as a convergence site for multiple extracellular signals known to induce plasticity in mature neurons ENSG00000291971 ENSG00000115904 PMC4881570__F2 MiRNAs in cardiac fibrosis pathway ENSG00000164056 ENSG00000163914 ENSG00000291748 ENSG00000168610 PMC6920353__F4 Blood transcriptome profile induced by an efficacious vaccine formulated with salivary antigens from cattle ticks ENSG00000159128 ENSG00000213928 ENSG00000108515 ENSG00000171940 ENSG00000180772 ENSG00000079432 ENSG00000166278 ENSG00000121807 ENSG00000186810 ENSG00000239732 ENSG00000115415 ENSG00000100302 ENSG00000132692 ENSG00000180616 ENSG00000185591 ENSG00000168398 ENSG00000146648 ENSG00000169375 PMC9185618__F2 Targeting the methionine addiction of cancer ENSG00000099810 PMC4498940__F3 Changes in the pRb and p53 pathway promoting cell cycle passage in high-grade central chondrosarcoma, as found in the present and previous studies ENSG00000135446 PMC5390360__F4 Interaction between AMPK and AKT on the phosphorylation: Growth factor activates TKR and promotes the activation of AKT via IRS1/PI3K/PDK1 signaling ENSG00000169047 PMC4881570__F3 MiRNAs in cardiomyocyte apoptosis pathway ENSG00000132906 ENSG00000156026 ENSG00000198793 ENSG00000136997 ENSG00000132478 ENSG00000067900 ENSG00000120868 ENSG00000171791 ENSG00000168610 ENSG00000164305 PMC5758710__F1 G10’s modified pathway diagram for the alfalfa lignin system ENSG00000121807 ENSG00000084774 PMC5390360__F2 ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway ENSG00000002330 ENSG00000042832 ENSG00000083290 ENSG00000198793 ENSG00000171791 ENSG00000159399 PMC5390360__F3 ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway ENSG00000177169 PMC5805998__F3 Functional enrichment of combined differentially expressed gene list in severe asthma across all tissues ENSG00000108691 ENSG00000140678 ENSG00000066336 ENSG00000170458 ENSG00000006451 ENSG00000177606 ENSG00000173039 ENSG00000069956 ENSG00000073756 ENSG00000277943 ENSG00000136826 ENSG00000062485 PMC8211286__F1 Schematic presentation of IL-6/JAK/STAT3 pathway in pancreatic cancer cells and tumor microenvironment ENSG00000168610 PMC8523922__F2 IL-36 in the Pathophysiological Processes of Autoimmune Diseases ENSG00000113520 ENSG00000172936 PMC7049637__F2 Proposed mechanisms involved in the anti-fibrotic activity of curcumin by inhibiting the activation of PSCs to acquire myofibroblast-like phenotypes PMC7049637__F3 Proposed mechanisms involved in the anti-fibrotic activity of rhein ENSG00000170558 ENSG00000164690 ENSG00000168610 ENSG00000146648 PMC3348440__F1 Target-derived NGF mediates axon growth and synapse assembly in sympathetic neurons via endocytic signaling mechanisms PMC4105941__F1 The Self-Limiting Dynamics of TGFB Signaling In Silico and In Vitro, with Negative Feedback through PPM1A Upregulation PMC2134838__F2 ALTERNATE ROUTES FOR DRUG DELIVERY TO THE CELL INTERIOR ENSG00000151532 PMC8812242__F6 Angiogenic content of microparticles in patients with diabetes and coronary artery disease predicts networks of endothelial dysfunction ENSG00000172005 ENSG00000183864 ENSG00000038002 PMC8612001__F3 Epigenetic modifications in thymic epithelial cells: an evolutionary perspective for thymus atrophy ENSG00000162552 ENSG00000170558 ENSG00000111186 PMC8898354__F1 Crosstalk between adipose tissue and the microbiota-gut-brain axis in metabolic diseases ENSG00000198576 ENSG00000131096 PMC8507396__F2 PLCG1 in regulation of VEGFR2 and FGFR1 signaling ENSG00000124181 ENSG00000077782 PMC8898354__F3 Crosstalk between adipose tissue and the microbiota-gut-brain axis in metabolic diseases ENSG00000198576 PMC9496810__F7 White Paper: Mimetics of Class 2 Tumor Suppressor Proteins as Novel Drug Candidates for Personalized Cancer Therapy ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5770468__F8 Model depicting the suggested signaling pathway modulated by CSs to inhibit HIV-1 gene expression ENSG00000162889 ENSG00000291971 ENSG00000146648 ENSG00000062485 PMC4132214__F1 Transcriptomic differences between OVCAR3 and SKOV3 and PCA after interaction with the mesenchymal cells ENSG00000065361 ENSG00000122691 ENSG00000173599 ENSG00000019549 ENSG00000221869 ENSG00000168779 ENSG00000157514 PMC2774854__F1 Schematic overview about TCR-dependent signalling pathways ENSG00000175938 ENSG00000213658 ENSG00000070831 ENSG00000167323 ENSG00000293604 ENSG00000010810 PMC4132214__F2 Pathways modified in OCC upon MSC contact related to adherence, migration, and invasion ENSG00000147162 ENSG00000140937 ENSG00000133110 ENSG00000149968 ENSG00000134215 ENSG00000050165 ENSG00000265972 ENSG00000137573 ENSG00000162772 ENSG00000112715 ENSG00000116962 PMC8140999__F5 Translational control by eIF2A phosphorylation ENSG00000144895 PMC8523993__F8 Performance Assessment of the Network Reconstruction Approaches on Various Interactomes ENSG00000140992 ENSG00000065675 ENSG00000291971 ENSG00000105647 ENSG00000140092 ENSG00000169032 ENSG00000121879 ENSG00000137764 ENSG00000012048 ENSG00000163558 ENSG00000150907 ENSG00000166501 ENSG00000123374 ENSG00000198670 ENSG00000105810 ENSG00000139687 ENSG00000140443 ENSG00000196712 ENSG00000136158 ENSG00000027075 ENSG00000262406 ENSG00000142192 ENSG00000133056 ENSG00000065361 ENSG00000065559 ENSG00000184481 ENSG00000139618 ENSG00000149311 ENSG00000066468 ENSG00000110395 ENSG00000135446 ENSG00000067606 ENSG00000171608 ENSG00000146648 PMC4586477__F2 TAA-specific CD8+ T cells often lack co-stimulation for an immune response against tumors ENSG00000291603 ENSG00000213658 ENSG00000070831 ENSG00000149269 ENSG00000010810 ENSG00000113263 ENSG00000141968 PMC11087724__F1 AMPK/mTOR signaling pathway involved in regulation of feed intake in chickens (created with BioRender ENSG00000198793 PMC11087724__F2 Leptin and insulin signaling pathways in the hypothalamus of chickens regulating neuropeptide genes (created with BioRender ENSG00000150907 ENSG00000169047 ENSG00000115138 ENSG00000168610 PMC11087724__F3 Detailed leptin signaling pathway in the hypothalamus of chickens (adapted from “Cytokine Signaling through the JAK-STAT Pathway”, by BioRender ENSG00000168610 PMC4586477__F5 Many signals overlap with PI3K/AKT/mTOR pathways in tumor-specific CD8+ T cells ENSG00000002330 ENSG00000105401 PMC7905169__F3 Regulation of NF-kB activation by ubiquitin ligases and DUBs ENSG00000157625 ENSG00000083799 ENSG00000175104 PMC6097464__F11 TGF-beta signaling highlighted in KEGG pathway analysis in parallel with SPIA pathway analysis by using microarray result of SNU-2414 set ENSG00000111537 ENSG00000186340 ENSG00000100387 ENSG00000113558 ENSG00000136997 ENSG00000163083 ENSG00000134363 ENSG00000185591 ENSG00000169231 ENSG00000137801 PMC7905169__F4 The regulation of TGFB pathway by ubiquitin ligases and DUBs ENSG00000135655 ENSG00000102226 ENSG00000198742 ENSG00000123124 PMC7230639__F1 Mechanisms of lactate-BDNF interaction following physical exercise ENSG00000160097 ENSG00000096717 PMC6097464__F10 MAPK signaling highlighted in KEGG pathway analysis in parallel with SPIA pathway analysis by using microarray result of SNU-2414 set ENSG00000185634 ENSG00000169291 ENSG00000002330 ENSG00000006712 ENSG00000112715 ENSG00000099942 ENSG00000185129 PMC6303891__F7 Putative mechanism is demonstrating how the loss of SEMA5A can trigger EMT ENSG00000168036 PMC3896784__F8 Model of FTO regulation of leptin action and glucose homeostasis through the LepRb-STAT3 signaling pathway ENSG00000168610 PMC5603666__F10 Graphic representation of pathways for furanodiene-induced cell apoptosis and for doxorubicin-resistant MCF-7 cells outcomes ENSG00000002330 PMC7807149__F6 Lycopene Production Pathway in Triple KOE ENSG00000197713 ENSG00000173599 ENSG00000047932 PMC10999658__F7 Molecular mechanism underlying CE accumulation in ccRCC and suppression of cancer progression upon CE depletion ENSG00000057252 ENSG00000134086 ENSG00000198793 PMC6778377__F6 Schematic illustrating how Nrf-2 activation regulates phenotypic modulation ENSG00000079999 PMC4388604__F1 WDFY1, a new player in the TLR-TRIF pathwayTLR3-stimulated signaling is fully dependent on TRIF, and TLR4 stimulates two signaling pathways, one of which is dependent on TRIF ENSG00000136869 ENSG00000164342 PMC3695741__F2 Nicotine and Pathological Angiogenesis ENSG00000133107 ENSG00000002330 ENSG00000144935 ENSG00000072315 PMC3764071__F1 One-carbon metabolism and glutathione (GSH) synthesis and metabolism ENSG00000148798 ENSG00000116984 PMC8482636__F7 Targeting INMT and interrupting its methylation pathway for the treatment of castration resistant prostate cancer ENSG00000178860 ENSG00000241644 PMC4313732__F2 Cytosolic nucleic acid pattern recognition and activation of ISGs ENSG00000184979 ENSG00000164430 ENSG00000088888 ENSG00000138135 ENSG00000115415 ENSG00000163568 ENSG00000163565 ENSG00000135828 ENSG00000125347 ENSG00000276561 PMC8434532__F4 Bypassing the Resistance Mechanisms of the Tumor Ecosystem by Targeting the Endoplasmic Reticulum Stress Pathway Using Ruthenium- and Osmium-Based Organometallic Compounds: An Exciting Long-Term Collaboration with Dr. Michel Pfeffer ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC6695817__F1 Mitochondrial antiviral signaling protein (MAVS)-dependent antiviral signaling pathway ENSG00000088888 ENSG00000185436 ENSG00000125347 PMC5380511__F7 A genome-wide loss-of-function screen identifies SLC26A2 as a novel mediator of TRAIL resistance ENSG00000172680 ENSG00000070831 ENSG00000050748 ENSG00000115904 ENSG00000169032 ENSG00000100485 ENSG00000121879 ENSG00000112242 ENSG00000071051 ENSG00000051180 ENSG00000105810 ENSG00000139687 ENSG00000132906 ENSG00000109320 ENSG00000065559 ENSG00000213341 ENSG00000168610 ENSG00000139618 ENSG00000017797 ENSG00000110395 ENSG00000115415 ENSG00000163235 ENSG00000135446 ENSG00000006451 ENSG00000144118 ENSG00000145349 PMC6115922__F1 Honey Bee Immune Pathways—Highlighting Genes Implicated in Antiviral Immune Responses ENSG00000168040 ENSG00000144406 ENSG00000123908 PMC4746893__F1 Cyclin D/cyclin-dependent kinase (CDK)4/6/retinoblastoma (Rb) Pathway and the cell cycle ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC6972667__F4 Linking the protein C pathway with EPCR‐ and ICAM‐1‐binding IEs in cerebral malaria ENSG00000110799 ENSG00000134982 ENSG00000100985 PMC8140811__F7 Protein Signature Predicts Response to Neoadjuvant Treatment With Chemotherapy and Bevacizumab in HER2-Negative Breast Cancers ENSG00000107562 ENSG00000148400 ENSG00000128052 ENSG00000100345 ENSG00000171791 ENSG00000091879 ENSG00000112715 ENSG00000154188 ENSG00000149554 ENSG00000146648 ENSG00000067369 ENSG00000121966 PMC6294046__F4 Druggable proteome across five classic cancer pathways ENSG00000157404 ENSG00000157764 ENSG00000138798 ENSG00000198793 ENSG00000121879 ENSG00000146648 PMC5337876__F10 Schematic diagram depicting proposed mechanism for the Wnt signaling pathway activation during differentiation of ADSCs into insulin-producing cells ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC8913504__F3 Metabolism Characteristics of Th17 and Regulatory T Cells in Autoimmune Diseases ENSG00000100385 ENSG00000134460 ENSG00000198793 ENSG00000049768 PMC6404501__F2 Autophagy: novel insights into therapeutic target of electroacupuncture against cerebral ischemia/ reperfusion injury ENSG00000198793 PMC2831127__F7 Proteins Secreted By Embryonic Stem Cells Activate Cardiomyocytes Through Ligand Binding Pathways ENSG00000019991 ENSG00000115457 ENSG00000146678 ENSG00000291761 ENSG00000168610 PMC7760417__F1 Virus entry initiates the interferon (IFN) response ENSG00000105397 ENSG00000185436 ENSG00000172005 ENSG00000172936 ENSG00000142166 PMC3678388__F1 Canonical ATR signaling pathway and functions of newly identified regulators.(A) ATR signaling is activated in response to single-stranded DNA gaps in the genome ENSG00000131944 ENSG00000175054 ENSG00000164053 ENSG00000094804 ENSG00000187790 ENSG00000110274 ENSG00000073111 ENSG00000076003 ENSG00000096401 ENSG00000100865 ENSG00000156273 PMC8324723__F1 Forecasting early onset diminished ovarian reserve for young reproductive age women ENSG00000177575 ENSG00000082175 ENSG00000242252 ENSG00000115138 ENSG00000173039 ENSG00000074319 ENSG00000124107 ENSG00000116030 ENSG00000168610 ENSG00000213523 PMC3678388__F3 ATR recruitment to some DNA base lesions proceeds through a mismatch repair-dependent mechanism.Mismatch repair proteins may contribute directly and indirectly to ATR recognition of some times of DNA damage ENSG00000175054 ENSG00000164053 PMC8156839__F1 Survey of Bacterial Microcompartment Distribution in the Human Microbiome ENSG00000113262 ENSG00000124493 ENSG00000164082 PMC6002666__F4 Predicted models for central metabolisms of A ENSG00000145020 ENSG00000254550 PMC9021375__F8 Lysophosphatidic Acid Receptor 3 Suppress Neutrophil Extracellular Traps Production and Thrombosis During Sepsis ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000198670 PMC9475012__F1 Neuroprotective effects of glucagon-like peptide 1 in Alzheimer’s and Parkinson’s disease: An in-depth review ENSG00000144895 ENSG00000169047 ENSG00000144848 ENSG00000168036 PMC7780227__F1 MAPK pathway: activators and inhibitors ENSG00000070831 ENSG00000163914 PMC2975271__F9 Schematic model for regulation of mTOR pathway signaling through interaction of the p53 target Plk2 with TSC proteins ENSG00000145632 ENSG00000198793 PMC8705144__F3 Hippo Pathway in Regulating Drug Resistance of Glioblastoma ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC5120213__F1 Schematic model of the three apoptosis signaling pathways ENSG00000178860 ENSG00000132906 ENSG00000175054 ENSG00000064012 ENSG00000164305 PMC8705144__F1 Hippo Pathway in Regulating Drug Resistance of Glioblastoma ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC9630567__F1 Involvement of endoplasmic reticulum stress in rifampicin-induced liver injury ENSG00000128272 ENSG00000100219 ENSG00000079999 PMC9613996__F5 Hypothesis of how loss of Gamma-secretase function causes ferroptotic stress ENSG00000283780 ENSG00000148400 ENSG00000167468 ENSG00000157193 ENSG00000250722 ENSG00000179918 PMC8236109__F1 Simulating ATO Mechanism and EGFR Signaling with Fuzzy Logic and Petri Net ENSG00000012048 ENSG00000094804 ENSG00000185591 ENSG00000146648 ENSG00000139618 PMC3425078__F5 Effects of NO and nitrosative stress on apoptosis ENSG00000120868 ENSG00000026103 PMC8236109__F2 Simulating ATO Mechanism and EGFR Signaling with Fuzzy Logic and Petri Net ENSG00000012048 ENSG00000094804 ENSG00000146648 ENSG00000139618 PMC2596245__F3 EET- or sEHI-mediated antihyperalgesia occurs through 2 distinct mechanisms PMC2882520__F3 Disease associations in the hypothalamus (genes regulated at p<0.001; fold change > ±1.5) ENSG00000118579 ENSG00000070915 ENSG00000110330 ENSG00000141744 ENSG00000073111 ENSG00000182326 ENSG00000291944 ENSG00000108561 ENSG00000198901 ENSG00000182511 ENSG00000134057 ENSG00000173599 ENSG00000004939 ENSG00000141456 PMC83988__F10 Signaling pathways for NFKB activation by IL-1B ENSG00000070831 ENSG00000172936 ENSG00000175104 PMC2570606__F6 Proposed model for the effects of hypoxia-induced energy stress on them TOR pathway in HNSCC cells ENSG00000198793 PMC5904076__F2 HSPs and the DNA damage response (DDR) ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000284774 PMC7930050__F7 GLI1 reduces drug sensitivity by regulating cell cycle through PI3K/AKT/GSK3/CDK pathway in acute myeloid leukemia ENSG00000135446 ENSG00000105810 PMC7563617__F5 Metformin-induced CSC suppression through AMPK activation and inhibition of protein prenylation by suppression of the mevalonate pathway ENSG00000160752 ENSG00000152904 ENSG00000198793 ENSG00000163914 ENSG00000197429 ENSG00000113161 ENSG00000104549 PMC10857240__F1 Proteins and genes involved in chlorophyll synthesis pathway ENSG00000080819 ENSG00000126088 ENSG00000256269 ENSG00000111341 ENSG00000188690 ENSG00000127948 PMC4200333__F9 Signaling pathways involved in TC adhesion-induced ICAM-1 expression on ECs under flow chamber conditions ENSG00000026508 ENSG00000185591 PMC6047913__F6 Enriched target genes of the TFs TCF7, RUNX1, STAT3, and SOX4 in the MAPK signaling pathway ENSG00000172680 ENSG00000170458 ENSG00000117400 ENSG00000177606 ENSG00000130159 ENSG00000196712 ENSG00000026103 PMC11940265__F6 Arachidonic acid metabolism pathway, with genes detected in ovary and testis transcriptomes ENSG00000108839 ENSG00000226275 ENSG00000096088 PMC4183126__F2 PALB2 links BRCA1 and BRCA2 into a pathway of products of breast cancer susceptibility genes ENSG00000012048 ENSG00000083093 ENSG00000051180 ENSG00000139618 PMC5904076__F6 HSPs and double strand break repair ENSG00000012048 ENSG00000105486 ENSG00000101751 ENSG00000284774 ENSG00000132646 ENSG00000051180 ENSG00000166169 ENSG00000139618 PMC2765790__F7 Nicotinamide phosphoribosyltransferase regulates cell survival through NAD+ synthesis in cardiac myocytes ENSG00000105835 ENSG00000096717 PMC11940265__F5 Oocyte meiosis signaling pathway, with genes detected in ovary and testis transcriptomes ENSG00000172680 ENSG00000066923 ENSG00000108055 ENSG00000285007 ENSG00000123374 ENSG00000166278 ENSG00000166851 ENSG00000127948 ENSG00000276876 PMC11958968__F3 Network representation of DSF, its modulated targets, and pathways involved in RF ENSG00000103811 ENSG00000162711 ENSG00000090534 ENSG00000137275 ENSG00000188257 ENSG00000198793 ENSG00000130649 ENSG00000100985 ENSG00000275565 ENSG00000073756 ENSG00000102468 ENSG00000124762 PMC12003521__F2 Mouse LrNK cells in other liver diseases (except for liver viral infection and liver cancer) ENSG00000169245 ENSG00000186810 ENSG00000164430 ENSG00000137033 PMC11958968__F5 Cluster analysis for DSF-modulated targets ENSG00000087245 ENSG00000181019 ENSG00000130649 ENSG00000008394 ENSG00000095303 ENSG00000126353 ENSG00000100985 ENSG00000162692 ENSG00000169919 ENSG00000275565 ENSG00000117322 ENSG00000121966 PMC3400941__F1 Model depicting PI3K signaling ENSG00000002330 ENSG00000169047 ENSG00000198793 PMC9654827__F8 Dynamin-like Protein 1 (DNML1) as a Molecular Target for Antibody-Based Immunotherapy to Treat Glaucoma ENSG00000074317 PMC5051518__F1 Simplified diagram of the adaptive and apoptotic pathways of ERS ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC11628441__F1 MTOR signaling pathway in astrocytes (simplified scheme) ENSG00000171105 ENSG00000148702 PMC5540209__F1 PSMA redirects MAPK to PI3K-AKT signaling to promote prostate cancer progression ENSG00000169047 ENSG00000140443 PMC4698658__F1 Genetic alterations in fatty acid transport and metabolism genes are associated with metastatic progression and poor prognosis of human cancers ENSG00000135218 ENSG00000198793 ENSG00000136997 ENSG00000154059 ENSG00000169710 ENSG00000078237 ENSG00000284194 ENSG00000079435 PMC6594283__F7 Possible signaling transduction pathways induced by SIRT7 in LPS-treated DCMECs ENSG00000187531 ENSG00000136869 PMC3667869__F1 Resistance to EGFR targeted therapies ENSG00000167601 ENSG00000146648 PMC5054714__F2 DEGs in cell cycle pathway Up-regulated and down-regulated DEGs are highlighted in red and green, respectively ENSG00000112576 ENSG00000105329 ENSG00000170027 ENSG00000164109 ENSG00000184182 ENSG00000250254 ENSG00000145386 ENSG00000134480 ENSG00000183765 ENSG00000175054 ENSG00000198176 ENSG00000132646 ENSG00000123374 ENSG00000147082 ENSG00000139687 ENSG00000080839 ENSG00000253729 ENSG00000175305 PMC7463613__F2 Notch signaling pathway in cancerogenic events ENSG00000148400 ENSG00000074181 PMC11202427__F1 BMP pathway in cardiomyocyte differentiation ENSG00000170365 ENSG00000016082 PMC3035565__F11 WNKs: atypical protein kinases with pleiotropic actions ENSG00000126562 ENSG00000149269 ENSG00000060237 ENSG00000165238 PMC11202427__F2 WNT signaling pathway ENSG00000134982 ENSG00000168036 PMC5054714__F1 DEGs in p53 signaling pathway Up-regulated and down-regulated genes are color-coded in red and green, respectively ENSG00000175054 ENSG00000002330 ENSG00000123374 ENSG00000111962 PMC8418611__F4 Several signaling pathways regulated by circRNAs in osteoporosis ENSG00000170365 ENSG00000137834 ENSG00000281324 ENSG00000162337 ENSG00000102871 ENSG00000134982 ENSG00000198742 ENSG00000168036 ENSG00000127191 PMC6781400__F7 Schematic illustration of the role of CyclinD1 to regulate Dicer promoter in ICC ENSG00000135446 ENSG00000105810 PMC4641790__F8 Mammalian target of rapamycin complex 1 (mTORC1) is required for mouse spermatogonial differentiation in vivo ENSG00000140992 ENSG00000157404 ENSG00000165643 ENSG00000108443 ENSG00000120669 ENSG00000187840 PMC7541099__F3 Putative mechanisms of SARS-CoV-2 infection ENSG00000140564 ENSG00000130234 ENSG00000184012 ENSG00000172936 ENSG00000100985 PMC8999129__F3 Novel Insights into Autophagy and Prostate Cancer: A Comprehensive Review ENSG00000198793 ENSG00000168036 ENSG00000168610 ENSG00000146648 PMC317204__F8 Schematic diagram illustrating a model for the antagonistic roles of Dp110 and DPTEN in Drosophila growth control ENSG00000169047 ENSG00000133124 PMC7541099__F2 Therapeutics under clinical trials targeting the cytokine storm in SARS-CoV-2 infection ENSG00000178860 ENSG00000130234 ENSG00000111837 ENSG00000172936 ENSG00000100985 ENSG00000168610 ENSG00000132693 PMC9141180__F2 Soyasapogenol C from Fermented Soybean (Glycine Max) Acting as a Novel AMPK/PPARA Dual Activator Ameliorates Hepatic Steatosis: A Novel SANDA Methodology ENSG00000144063 ENSG00000114200 ENSG00000178999 ENSG00000181104 ENSG00000120088 ENSG00000087085 ENSG00000113161 ENSG00000087586 ENSG00000196396 ENSG00000168522 ENSG00000149295 ENSG00000126218 ENSG00000143801 ENSG00000082175 ENSG00000129214 ENSG00000205155 ENSG00000123374 ENSG00000082556 ENSG00000100504 ENSG00000113263 ENSG00000177084 ENSG00000112742 ENSG00000184304 ENSG00000167434 ENSG00000027075 ENSG00000104365 ENSG00000142192 ENSG00000188822 ENSG00000157764 ENSG00000120915 ENSG00000213341 ENSG00000164082 ENSG00000099194 ENSG00000140465 ENSG00000063176 ENSG00000117020 ENSG00000117480 ENSG00000015520 ENSG00000164362 ENSG00000145321 ENSG00000170989 ENSG00000146648 ENSG00000198355 ENSG00000149503 PMC11668946__F1 Ferroptosis in ischemic stroke: Animal models and mechanisms ENSG00000168003 ENSG00000142192 ENSG00000161905 ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000137055 PMC11668946__F3 AA participates in the deacylation/reacylation cycle of membrane phospholipidscPLA2A cleaves glycerophospholipid molecules at the sn-2 position to produce AA ENSG00000111684 PMC7680860__F2 Synthetic CO2 fixation pathways for acetyl-CoA synthesis ENSG00000197713 PMC3085878__F3 TLR-induced microbial resistance ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000134070 ENSG00000136869 ENSG00000131323 ENSG00000125347 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC7599540__F4 Src Homology Region 2 Domain-Containing Phosphatase-2 (SHP-2) targeting on melanoma cells ENSG00000019991 ENSG00000138798 PMC5297719__F1 Molecular Biomarkers for Prediction of Targeted Therapy Response in Metastatic Breast Cancer: Trick or Treat? ENSG00000291971 ENSG00000105723 ENSG00000140443 PMC3356073__F1 Phosphatidylinositol 3-kinase (PI3K) signaling cascade ENSG00000002330 ENSG00000198793 ENSG00000164327 PMC6723883__F4 model of CFHR1-3 participation in Andes orthohantavirus (ANDV) infection response ENSG00000116785 ENSG00000101307 ENSG00000244414 PMC4050365__F5 Single-stranded RNA loading to AGO-clade Argonaute proteins ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC4325211__F3 Placental oxidative stress triggers the expression of transcription factors to regulate angiogenesis and trophoblast invasion ENSG00000102349 ENSG00000185591 ENSG00000168610 PMC8154696__F10 An overview of ODE exposure induced mitochondrial dysfunction in microglia and BSCs ENSG00000239732 ENSG00000164430 ENSG00000116688 ENSG00000158828 ENSG00000171109 PMC6136429__F3 CIN activates cGAS-STING signaling ENSG00000104856 ENSG00000182578 ENSG00000183735 ENSG00000164430 ENSG00000173039 ENSG00000131323 ENSG00000127191 PMC8564337__F6 Reduced MAGI3 level by HPV18E6 contributes to Wnt/B‐catenin signaling activation and cervical cancer progression ENSG00000081026 ENSG00000168036 PMC7224363__F1 Chemical reactions triggered by Δ9-fatty acyl-CoA desaturase, EC:1.14.19.1, also known as Stearoyl-CoA-desaturases (SCD), introducing a double bond and thus affecting lipid metabolism ENSG00000163930 ENSG00000281324 ENSG00000134982 ENSG00000167468 ENSG00000113161 ENSG00000174804 ENSG00000168036 ENSG00000026103 PMC9927011__F1 Gut microbiota: A novel and potential target for radioimmunotherapy in colorectal cancer ENSG00000081041 ENSG00000163739 ENSG00000168610 PMC3581799__F5 Cell-to-cell signaling network generated by ingenuity pathway analysis of differentially expressed genes: Molecules are represented as nodes, and the biological relationship between two nodes is represented as an edge (line) ENSG00000277336 ENSG00000140678 ENSG00000135218 ENSG00000100906 ENSG00000119535 ENSG00000081237 ENSG00000163220 ENSG00000124491 ENSG00000150337 ENSG00000258227 ENSG00000143226 ENSG00000158869 ENSG00000007171 ENSG00000115884 ENSG00000069482 ENSG00000140379 ENSG00000166523 ENSG00000125538 ENSG00000188404 ENSG00000108688 ENSG00000163734 ENSG00000028137 PMC9927011__F2 Gut microbiota: A novel and potential target for radioimmunotherapy in colorectal cancer ENSG00000164430 ENSG00000163599 PMC5465238__F1 Schematic outline of intracellular Ras signaling pathways in the suprachiasmatic nucleus (SCN) regulating circadian clockwork ENSG00000132326 ENSG00000179094 PMC8998406__F1 Notch Signaling Pathway by Bioactive Dietary Agents ENSG00000125398 ENSG00000148400 ENSG00000137845 PMC2376243__F8 Schematic mechanism of AB oligomer-mediated aberrant PAK activation and translocation in Alzheimer disease pathogenesis ENSG00000156299 ENSG00000010810 PMC7281445__F1 Tumor Necrosis Factor (TNF)/TNF-Receptor 1 (TNFR1)-mediated signalling and cell death checkpoints ENSG00000137275 ENSG00000102871 ENSG00000168404 ENSG00000285379 PMC5002480__F1 Cross talk between multiple signaling pathways involved in tumor progression and resistance ENSG00000149311 ENSG00000175054 ENSG00000163914 ENSG00000139618 PMC6966522__F2 The IL7R structure and signaling mechanism ENSG00000105639 PMC2949446__F1 Luteolin and gefitinib regulation of EGF Signaling Pathway and Cell Cycle Pathway genes in PC-3 human prostate cancer cells ENSG00000138798 PMC8610132__F7 miR-6745-TIMP1 axis inhibits cell growth and metastasis in gastric cancer ENSG00000168036 PMC6491685__F1 Complement system ENSG00000203710 ENSG00000166278 PMC3561537__F6 Scheme of EGFR signaling pathway activated by NEU3-induced GM3 reduction ENSG00000162139 ENSG00000138798 ENSG00000146648 PMC7717145__F1 Disease-based pathway analysis of genes involved in the pathogenesis of lung diseases and respiratory failure ENSG00000023734 ENSG00000130234 ENSG00000164400 ENSG00000136869 ENSG00000168484 ENSG00000103241 ENSG00000136352 ENSG00000001626 ENSG00000113525 ENSG00000165471 PMC3580961__F2 Transcription at damaged DNA ENSG00000132646 ENSG00000163945 ENSG00000136936 PMC8472588__F9 ALK-Negative Anaplastic Large Cell Lymphoma: Current Concepts and Molecular Pathogenesis of a Heterogeneous Group of Large T-Cell Lymphomas ENSG00000178860 ENSG00000134460 ENSG00000116815 ENSG00000105397 ENSG00000136997 ENSG00000137265 ENSG00000047936 ENSG00000168610 PMC4598026__F5 Tumor Necrosis Factor Alpha and Insulin-Like Growth Factor 1 Induced Modifications of the Gene Expression Kinetics of Differentiating Skeletal Muscle Cells ENSG00000091704 ENSG00000138449 ENSG00000123572 ENSG00000197632 ENSG00000137872 ENSG00000176971 ENSG00000137766 ENSG00000077274 ENSG00000169116 ENSG00000162641 ENSG00000145721 ENSG00000164237 ENSG00000075223 ENSG00000172346 ENSG00000092421 PMC9900921__F7 Simplified de novo sphingolipid biosynthesis pathway ENSG00000103089 ENSG00000090402 ENSG00000119537 ENSG00000148154 PMC3906547__F1 Reverse cholesterol transport pathway delivers free cholesterol from macrophages or other cells to the liver or intestine for excretion ENSG00000130164 ENSG00000100979 PMC9635594__F3 Schematic diagram showing the role of mucins in cancer metabolism ENSG00000012048 ENSG00000074800 ENSG00000078237 ENSG00000173702 ENSG00000169299 ENSG00000159399 PMC11083431__F6 Possible gene expression changes from enhanced NRF2 signaling and depleted NOTCH signaling in the bile acid synthetic pathway from cholesterol in Keap1F/F::RbpjF/F::AlbCre liver at 3 W of age ENSG00000167910 ENSG00000180432 ENSG00000073734 ENSG00000197063 ENSG00000106459 ENSG00000135929 PMC7545792__F8 Map of Th17 cell signature cytokines and the IL-17 signaling transduction pathway ENSG00000148346 ENSG00000081041 ENSG00000102871 ENSG00000163739 ENSG00000285433 ENSG00000163220 ENSG00000168040 ENSG00000155313 ENSG00000127191 ENSG00000163702 ENSG00000169245 ENSG00000183735 ENSG00000108691 ENSG00000111537 ENSG00000102970 ENSG00000108688 ENSG00000163734 ENSG00000131323 ENSG00000056736 ENSG00000115009 PMC6071257__F1 Epstein–Barr virus (EBV) oncoproteins affecting p53 signaling pathways ENSG00000111653 PMC8065646__F3 Examples of redox regulation of specific transcription factors ENSG00000139515 ENSG00000106331 ENSG00000079999 PMC8065646__F4 Redox targets within insulin secretory pathway and proteins involved in extracellular redox signaling ENSG00000079387 ENSG00000144935 ENSG00000130234 ENSG00000086991 ENSG00000072315 ENSG00000174611 ENSG00000105227 PMC9687473__F1 Targeting Adiponectin in Breast Cancer ENSG00000026103 PMC12011584__F1 VEGF signaling pathway in stimulating sngiogenesis (By Figdraw2 ENSG00000118257 ENSG00000150630 PMC9635594__F1 Schematic diagram showing the mucins role in cancer stemness and chemoresistance ENSG00000291363 ENSG00000281324 ENSG00000180543 ENSG00000026508 ENSG00000168036 ENSG00000135363 ENSG00000171791 ENSG00000168610 ENSG00000146648 ENSG00000145113 ENSG00000173702 ENSG00000121966 PMC9635594__F2 Mucin’s role in epithelial to mesenchymal transition (EMT) ENSG00000291363 ENSG00000170558 ENSG00000168610 ENSG00000145113 PMC7597043__F1 Mechanisms of venetoclax resistance ENSG00000186716 ENSG00000171791 ENSG00000010671 PMC5425748__F2 Illustration of the multiple signalling pathways for TGFB in the VSMC In the normal state, TGFB is sequestered by microfibrils, bound to fibrillin-1 through LTBP-1 and fibulin-4 interactions, until its required release ENSG00000049323 PMC7599957__F1 Network diagram of the model ENSG00000160752 ENSG00000110921 ENSG00000130164 ENSG00000197429 ENSG00000120437 ENSG00000167508 PMC4894418__F5 Profiling status epilepticus-induced changes in hippocampal RNA expression using high-throughput RNA sequencing ENSG00000087095 ENSG00000170458 ENSG00000127191 ENSG00000026103 PMC7716161__F3 Role of IL-17 in the pathogenesis of acinar duct metaplasia, pancreatic intraepithelial neoplasia, and pancreatic cancer ENSG00000133083 ENSG00000148926 PMC6497964__F8 The signaling pathway from EPHB6 to catecholamine biosynthesis in AGCCs ENSG00000106123 ENSG00000090776 PMC10820593__F5 Common adjuvants and proposed mechanisms ENSG00000142192 ENSG00000164430 ENSG00000276561 PMC5391303__F1 Pharmacokinetic and pharmacodynamic evaluation of ibrutinib for the treatment of chronic lymphocytic leukemia: rationale for lower doses ENSG00000186716 ENSG00000197943 ENSG00000010671 ENSG00000121966 PMC8513284__F10 FAM49B promotes breast cancer proliferation, metastasis, and chemoresistance by stabilizing ELAVL1 protein and regulating downstream Rab10/TLR4 pathway ENSG00000066044 ENSG00000168036 ENSG00000136869 ENSG00000084733 PMC4491123__F1 The miRNA biogenesis and function ENSG00000139546 ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC8946846__F9 Failure Analysis of TEVG’s II: Late Failure and Entering the Regeneration Pathway ENSG00000110799 ENSG00000184216 PMC11172514__F1 The mechanism regulating NLRP3 inflammasome activation in canonical, non-canonical, and alternate pathway ENSG00000278718 ENSG00000162711 ENSG00000172936 ENSG00000168040 ENSG00000175104 ENSG00000064012 ENSG00000184216 PMC10513492__F7 Lipid and atherosclerosis and (B) AGE-RAGE signaling pathway in diabetic complications map of Chaihu Anxin Capsule for their potential treatment of depression ENSG00000162711 ENSG00000188404 ENSG00000150455 PMC4062707__F2 Signalling pathways activated by chemokine receptors ENSG00000070831 ENSG00000291971 ENSG00000149269 ENSG00000198793 ENSG00000177606 ENSG00000067900 PMC1480427__F1 ω3 LC-PUFA and ω6 LC-PUFA biosynthetic pathways ENSG00000026103 PMC7812220__F8 Protein-protein interaction network of hsa-miR-126-5p-related differentially expressed genes ENSG00000128016 ENSG00000145147 ENSG00000127528 ENSG00000103241 ENSG00000072571 ENSG00000164879 ENSG00000150681 ENSG00000188817 ENSG00000263155 ENSG00000183607 ENSG00000196549 ENSG00000064989 ENSG00000176435 ENSG00000163421 ENSG00000181631 ENSG00000166482 ENSG00000091844 ENSG00000136869 ENSG00000136155 ENSG00000078098 ENSG00000171885 ENSG00000135604 ENSG00000137648 ENSG00000096088 ENSG00000163736 ENSG00000007908 ENSG00000257335 ENSG00000166670 ENSG00000073756 ENSG00000144354 ENSG00000164736 ENSG00000109805 ENSG00000136160 ENSG00000134531 PMC7812220__F9 Protein-protein interaction network ENSG00000118526 ENSG00000127528 ENSG00000163736 ENSG00000007908 ENSG00000143228 ENSG00000166670 ENSG00000162772 ENSG00000144354 ENSG00000072571 ENSG00000213949 ENSG00000156970 ENSG00000134057 ENSG00000109805 ENSG00000280610 ENSG00000137573 ENSG00000152952 ENSG00000078098 PMC5610833__F1 Catecholamine synthesis pathway ENSG00000123454 ENSG00000141744 PMC4344511__F4 Estimation of multi-factor mediated dysregulations affected by the module ENSG00000182718 ENSG00000157404 ENSG00000129515 ENSG00000148798 ENSG00000138798 ENSG00000105656 ENSG00000135407 ENSG00000166278 ENSG00000146648 ENSG00000148848 ENSG00000102974 ENSG00000106546 PMC8449320__F7 FGF-2–dependent signaling activated in aged human skeletal muscle promotes intramuscular adipogenesis ENSG00000113140 ENSG00000177606 ENSG00000078098 PMC4417485__F1 Fission Yeast-based Platform for Phosphodiesterase Inhibitor HTSs and Analyses of Phosphodiesterase Activity PMC9600294__F5 Adipokines as Regulators of Autophagy in Obesity-Linked Cancer ENSG00000177169 ENSG00000130164 ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC8350063__F7 LGI1 governs neuritin-mediated resilience to chronic stress ENSG00000108231 ENSG00000169047 ENSG00000291761 ENSG00000108840 PMC8640120__F1 Pro- and Anti- Effects of Immunoglobulin A- Producing B Cell in Tumors and Its Triggers ENSG00000145321 PMC11800652__F5 Metabolic maps of Sulfurovum species from Kebrit Deep BSI ENSG00000137996 ENSG00000127948 PMC5471512__F8 Insulin resistance in LMC metabolism, inflammation, and contractility ENSG00000169047 ENSG00000132478 PMC6701246__F1 Mechanisms promoting macrophage phagocytosis of AC by lipid mediators ENSG00000125538 ENSG00000163914 ENSG00000171049 ENSG00000125245 ENSG00000168610 PMC5439269__F3 Eukaryotic DNA mismatch repair (MMR) ENSG00000132646 ENSG00000177084 ENSG00000095002 ENSG00000122512 PMC5413367__F1 Targeting molecular pathway ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC6908425__F2 Deletion of fumarases leads to changes in carbon fluxes and amounts of metabolic enzymes ENSG00000143252 ENSG00000197713 ENSG00000122966 ENSG00000172005 ENSG00000153574 PMC8072122__F1 Curcumin Regulates Cancer Progression: Focus on ncRNAs and Molecular Signaling Pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC6908425__F4 Deletion of glycogen synthase in a ΔfumABC strain restores carbon fluxes without changes in amounts of metabolic enzymes ENSG00000143252 ENSG00000197713 ENSG00000122966 ENSG00000172005 ENSG00000153574 ENSG00000162924 PMC9315443__F5 Revolution of CAR Engineering For Next-Generation Immunotherapy In Solid Tumors ENSG00000139193 ENSG00000172936 ENSG00000276561 PMC4668848__F2 Influence of MAP on TLR9 signaling ENSG00000239732 ENSG00000291971 ENSG00000149269 ENSG00000134070 ENSG00000172936 ENSG00000131323 ENSG00000168040 ENSG00000175104 ENSG00000184216 PMC4234068__F1 COMPLEMENT REGULATION IN RENAL DISEASE MODELS ENSG00000039537 ENSG00000113600 ENSG00000203710 ENSG00000166278 PMC7444072__F5 Interaction networks of DMCs according to severe features of PE ENSG00000169302 ENSG00000243414 ENSG00000165626 ENSG00000265681 ENSG00000108001 ENSG00000196090 ENSG00000129965 ENSG00000171345 ENSG00000038427 ENSG00000171435 ENSG00000163710 ENSG00000198010 ENSG00000155530 ENSG00000133961 ENSG00000147647 ENSG00000168404 ENSG00000174963 ENSG00000185008 ENSG00000135298 ENSG00000172530 ENSG00000113360 ENSG00000072080 PMC4904104__F5 Disturbed metabolic pathway related to NAFLD and HD-TE treatment ENSG00000042832 ENSG00000173599 ENSG00000198670 ENSG00000156471 ENSG00000133027 PMC6261473__F1 Nrf2–Keap1 signaling pathway ENSG00000178573 ENSG00000079999 PMC12073235__F1 Primary to specialized metabolic flow in Cannabis ENSG00000148832 PMC3568263__F2 Defective counterregulation and hypoglycemia unawareness in diabetes: Mechanisms and emerging treatments ENSG00000198576 PMC4905266__F1 Intersection between the Ras and the SUMO pathway in cancer ENSG00000142230 PMC8577254__F2 Retinoic acid in the commitment to meiosis ENSG00000095596 ENSG00000187553 ENSG00000184254 ENSG00000003137 ENSG00000121039 ENSG00000128918 PMC3218933__F3 Embryonic pathway signaling leads to induction of epithelial-to-mesenchymal transition ENSG00000167601 ENSG00000128917 ENSG00000122691 ENSG00000138798 ENSG00000185669 ENSG00000102349 ENSG00000019549 ENSG00000288335 ENSG00000168036 ENSG00000184916 ENSG00000128602 ENSG00000090932 PMC3218933__F2 Cross-talk among embryonic signaling pathways and experimental inhibitors ENSG00000050165 ENSG00000168036 ENSG00000104332 ENSG00000184916 ENSG00000114315 ENSG00000128602 ENSG00000163501 PMC5390606__F2 A simplified network identified by IPA pathway ENSG00000134057 PMC9013942__F2 Celastrol: An Update on Its Hepatoprotective Properties and the Linked Molecular Mechanisms ENSG00000284774 ENSG00000096717 ENSG00000127191 PMC9013942__F3 Celastrol: An Update on Its Hepatoprotective Properties and the Linked Molecular Mechanisms ENSG00000291971 ENSG00000168610 ENSG00000121966 PMC4339951__F1 TGFB pathway in muscular dystrophy ENSG00000118785 PMC3475374__F1 Conceptual schematic of M ENSG00000127948 ENSG00000116984 PMC7610648__F3 Replication-coupled ICL repair ENSG00000131944 ENSG00000109674 ENSG00000188827 PMC7196371__F12 Functions of exercise in AD ENSG00000171720 ENSG00000125538 ENSG00000196591 PMC8485521__F3 MicroRNAs as the critical regulators of Cisplatin resistance in ovarian cancer cells PMC8883456__F6 Main repair pathways for trapped topoisomerases in humans ENSG00000143799 ENSG00000010072 ENSG00000166801 ENSG00000063978 ENSG00000146063 ENSG00000147174 ENSG00000042088 PMC8485521__F2 MicroRNAs as the critical regulators of Cisplatin resistance in ovarian cancer cells ENSG00000198793 PMC9569450__F1 Dual Effect of Tryptamine on Prostate Cancer Cell Growth Regulation: A Pilot Study ENSG00000162882 ENSG00000183077 PMC8385797__F5 Smoking induces sex-specific changes in the small airway proteome ENSG00000070404 ENSG00000107742 ENSG00000196352 PMC7281786__F5 Mitochondrial mediated immune functions and cell signaling ENSG00000162711 ENSG00000239732 ENSG00000088888 ENSG00000111537 ENSG00000125538 ENSG00000171051 PMC9280276__F2 Targeting Ferroptosis Pathway to Combat Therapy Resistance and Metastasis of Cancer ENSG00000168003 ENSG00000151012 ENSG00000125144 ENSG00000167468 ENSG00000198793 ENSG00000146648 PMC9280276__F3 Targeting Ferroptosis Pathway to Combat Therapy Resistance and Metastasis of Cancer ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000187855 PMC9280276__F1 Targeting Ferroptosis Pathway to Combat Therapy Resistance and Metastasis of Cancer ENSG00000168003 ENSG00000151012 ENSG00000143761 ENSG00000167468 ENSG00000072274 ENSG00000115271 ENSG00000168610 ENSG00000123983 PMC5364922__F7 Serum microRNA profiling and bioinformatics analysis of patients with type 2 diabetes mellitus in a Chinese population ENSG00000109819 ENSG00000171105 ENSG00000162409 ENSG00000150907 ENSG00000169047 ENSG00000108443 ENSG00000169032 ENSG00000132356 ENSG00000160691 PMC9280276__F4 Targeting Ferroptosis Pathway to Combat Therapy Resistance and Metastasis of Cancer ENSG00000168003 ENSG00000092445 ENSG00000115415 ENSG00000167468 ENSG00000110651 ENSG00000125347 ENSG00000184500 PMC11231459__F2 Tumor progression targeting PDGFR-B signaling pathway, contributed to the pathogenesis of DFSP (created with Biorender.com) ENSG00000115415 ENSG00000198793 ENSG00000108821 PMC9280276__F5 Targeting Ferroptosis Pathway to Combat Therapy Resistance and Metastasis of Cancer ENSG00000168003 ENSG00000147649 ENSG00000186575 ENSG00000124216 ENSG00000151012 ENSG00000122691 ENSG00000167468 ENSG00000072274 PMC11231459__F5 Understanding of FGFs/FGFR signaling pathway in pathogenesis of DFSP (created with Biorender.com) ENSG00000066468 ENSG00000077782 PMC9519154__F1 Exploring autophagy-related prognostic genes of Alzheimer’s disease based on pathway crosstalk analysis ENSG00000172680 ENSG00000142192 ENSG00000002330 ENSG00000166402 ENSG00000173611 ENSG00000156026 ENSG00000007908 ENSG00000087842 ENSG00000166278 ENSG00000168040 ENSG00000164305 PMC10375783__F2 Ferroptosis: a novel regulated cell death participating in cellular stress response, radiotherapy, and immunotherapy ENSG00000149311 ENSG00000164430 ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000127948 PMC10375783__F3 Ferroptosis: a novel regulated cell death participating in cellular stress response, radiotherapy, and immunotherapy ENSG00000168003 ENSG00000149311 ENSG00000111537 ENSG00000151012 ENSG00000105329 ENSG00000115415 ENSG00000111684 ENSG00000189403 PMC11985419__F9 ICAM-1-Mac-1 mediated NET formation mechanism in response to LPS or LTA ENSG00000226275 ENSG00000122966 ENSG00000136869 PMC9535304__F4 Molecular activity of cannabidiol in the regulation of Nrf2 system interacting with NFKB pathway under oxidative stress ENSG00000171720 ENSG00000198517 ENSG00000175104 ENSG00000079999 PMC2685460__F7 Induction of Distinct TLR2-Mediated Proinflammatory and Proadhesive Signaling Pathways in Response to Porphyromonas gingivalis Fimbriae ENSG00000170458 ENSG00000172936 ENSG00000150455 PMC4491123__F2 Targets of miRNAs in different cell types of developing mouse lungs ENSG00000103479 ENSG00000156299 ENSG00000148400 ENSG00000074181 ENSG00000134982 ENSG00000196935 ENSG00000164690 ENSG00000128602 ENSG00000124762 ENSG00000141298 PMC3440872__F4 Model showing a role for Yap in governing cardiac growth and survival by interlinking the Hippo, IGF, and Wnt pathways ENSG00000134982 ENSG00000168036 ENSG00000150457 ENSG00000131023 ENSG00000140443 PMC10373097__S1 Rationally designed cancer vaccine based on NIR-II fluorescence image-guided light-triggered remote control of antigen cross-presentation and autophagy ENSG00000198793 PMC6797510__F10 HOTAIR competitively binds to miR‐206, thereby promoting STC2 expression, activating PI3K/AKT signalling pathway ENSG00000123908 PMC5964020__F2 Cortisol and catecholamine metabolism ENSG00000123454 ENSG00000141744 PMC7936909__F7 Most correlated MAPK signaling pathway enriched in KEGG mapper PMC2756058__F1 Pathway of cellular processing of cobalamin (OH-cbl) and location of main enzyme defects in the pathway leading to methylmalonic acidemias and cobalamin metabolic disorders ENSG00000110395 ENSG00000124370 ENSG00000151611 ENSG00000168288 ENSG00000132763 PMC6274736__F1 Schematic diagram of c-mesenchymal–epithelial transition (c-MET) activation signaling pathways ENSG00000019991 ENSG00000168610 ENSG00000146648 PMC6274736__F2 Targeting HGF/c-MET pathway in digestive system cancers by microRNAs ENSG00000019991 ENSG00000087245 ENSG00000198793 ENSG00000112715 ENSG00000168610 PMC3435197__F2 Spectrum of somatic mitochondrial mutations in five cancers PMC8584253__F7 PDK1 Inhibitor BX795 Improves Cisplatin and Radio-Efficacy in Oral Squamous Cell Carcinoma by Downregulating the PDK1/CD47/Akt-Mediated Glycolysis Signaling Pathway ENSG00000198793 ENSG00000136997 PMC3549672__F2 Ubiquitination in Signaling to and Activation of IKK ENSG00000197530 ENSG00000121060 ENSG00000101752 PMC8519338__F1 Macrophage Activation Syndrome and COVID 19: Impact of MAPK Driven Immune-Epigenetic Programming by SARS-Cov-2 ENSG00000170458 ENSG00000130234 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC4104414__F1 Figure shows the endothelial response to a high salt diet ENSG00000105329 PMC3549672__F3 Ubiquitination in Signaling to and Activation of IKK ENSG00000175104 PMC4453619__F7 Molecular genetic model (adapted from ; ; ; ) ENSG00000281324 ENSG00000163251 ENSG00000162337 ENSG00000168036 PMC7738893__F1 Action of monoclonal antibodies (mAb) in cancer therapy ENSG00000291603 ENSG00000070831 ENSG00000291971 ENSG00000134982 ENSG00000163599 ENSG00000198793 ENSG00000168040 ENSG00000112715 ENSG00000168610 PMC7738893__F3 Molecular mechanisms for impaired antibody therapeutic activity in cancer ENSG00000039537 PMC6302140__F11 Schematic depicting the proposed molecular mechanism by which citrate regulates cellular redox signaling pathways in BMSCs ENSG00000131174 ENSG00000118680 ENSG00000181523 ENSG00000111711 ENSG00000100554 ENSG00000107223 PMC9634730__F1 Targeting the regulation of aberrant protein production pathway in gastrointestinal cancer treatment ENSG00000136997 ENSG00000049768 PMC9535304__F2 Molecular activity of cannabidiol in the regulation of Nrf2 system interacting with NFKB pathway under oxidative stress ENSG00000178573 ENSG00000100387 ENSG00000156273 ENSG00000079999 PMC8605525__F8 Overexpression of E3 ubiquitin ligase Cbl attenuates endothelial dysfunction in diabetes mellitus by inhibiting the JAK2/STAT4 signaling and Runx3-mediated H3K4me3 ENSG00000138378 ENSG00000020633 PMC4012776__F1 Trim21 negatively regulates the DDX41-mediated signaling pathway ENSG00000132109 ENSG00000183735 ENSG00000276561 PMC9099524__F5 Hypoxia as a Modulator of Inflammation and Immune Response in Cancer ENSG00000134086 ENSG00000291971 ENSG00000138798 ENSG00000125538 ENSG00000175104 ENSG00000168610 PMC3591623__F7 Model for the putative mechanism by which Fsk-cAMPi negatively regulates IL-2R signaling in human T-cells ENSG00000105639 PMC7189297__F1 Relationship between EPO and FGF23 metabolism ENSG00000118972 ENSG00000099194 PMC6984609__F1 Role of autophagy in the maintenance of intestinal homeostasis and potential mechanisms by which defective autophagy may contribute to CD development ENSG00000171855 ENSG00000162711 ENSG00000123240 ENSG00000167207 ENSG00000198793 ENSG00000237693 ENSG00000213341 ENSG00000171791 ENSG00000150455 ENSG00000049768 ENSG00000164305 ENSG00000150782 ENSG00000178607 ENSG00000130881 ENSG00000125538 ENSG00000165376 ENSG00000128829 ENSG00000136869 ENSG00000104388 PMC9099524__F1 Hypoxia as a Modulator of Inflammation and Immune Response in Cancer ENSG00000087245 ENSG00000134086 PMC9099524__F2 Hypoxia as a Modulator of Inflammation and Immune Response in Cancer ENSG00000125538 ENSG00000168610 PMC6109480__F1 PD-1/PD-L1 signaling and reprograming in T cells ENSG00000159224 ENSG00000213658 ENSG00000134982 ENSG00000198793 PMC6689979__F2 Subcellular compartmentalization of sphingolipid metabolism ENSG00000157933 ENSG00000118785 ENSG00000119537 PMC8641543__F5 Inhibitors of nucleotide synthesis ENSG00000284320 ENSG00000065911 ENSG00000144659 ENSG00000100714 ENSG00000092621 ENSG00000164466 ENSG00000102967 ENSG00000120254 ENSG00000196517 PMC3307959__F5 Unconventional roles of kinesins in cell signaling ENSG00000066735 ENSG00000142192 ENSG00000122966 ENSG00000128602 PMC6383653__F6 Signaling pathway activated by OxPAPC ENSG00000291971 ENSG00000149269 ENSG00000010810 ENSG00000136936 PMC4604749__F4 Life cycle and pathogenesis of human cytomegalovirus infection: lessons from proteomics ENSG00000165119 ENSG00000130311 PMC6383653__F4 Proposed model for the cross-talk between HGF/c-Met and SphK1/S1P/Spns2/S1P1 signaling axis in HGF-mediated lamellipodia formation ENSG00000019991 ENSG00000183018 PMC3128772__F6 Cell signaling between rNSCs and hMSCs in coculture ENSG00000105329 ENSG00000074181 ENSG00000131095 PMC4633353__F7 Constitutive control of AKT-1 gene expression by JUNB / CJUN in ALK+ anaplastic large cell lymphoma: a novel crosstalk mechanism ENSG00000291971 ENSG00000198793 ENSG00000177606 ENSG00000105639 ENSG00000168610 PMC7726326__F7 Gene interaction network of upregulated and downregulated DEGs in TP-treated PC1 (A,B, respectively) and PC2 cells (C,D, respectively) identified by STRING software using a high confidence interaction score (0.700) ENSG00000131473 ENSG00000125740 ENSG00000092853 ENSG00000119969 ENSG00000073111 ENSG00000291348 ENSG00000111641 ENSG00000123219 ENSG00000104368 ENSG00000160752 ENSG00000116133 ENSG00000149968 ENSG00000143476 ENSG00000104549 ENSG00000122862 PMC3599046__F2 Toll-like receptor signaling pathway in response to MDV infection ENSG00000065717 ENSG00000170458 ENSG00000105656 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000143387 PMC7761032__F2 Potentials and Pitfalls of a Human Cervical Organoid Model Including Langerhans Cells ENSG00000138378 ENSG00000105397 ENSG00000105639 ENSG00000127191 ENSG00000168610 PMC3599046__F1 JAK/STAT signaling pathway in response to MDV infection ENSG00000127445 PMC9030480__F2 Translational Strategies to Target Metastatic Bone Disease ENSG00000152266 ENSG00000108691 PMC3917750__F1 Dual regulatory effect of proprotein convertase subtilisin/kexin type 9 (PCSK9) on neuronal apoptosis ENSG00000169174 PMC5256122__F1 Representation showing the mutations associated with the RAS/RAF/MEK/ERK pathway observed in melanoma ENSG00000157764 ENSG00000135446 ENSG00000198793 ENSG00000088256 ENSG00000105810 PMC6400990__F2 Schematic overview of glycine metabolism and six genetic loci for glycine in/near genes encoding enzymes related to glycine metabolism ENSG00000291958 ENSG00000092621 ENSG00000146733 ENSG00000178445 PMC8745614__F5 Reduced RBPMS Levels Promote Cell Proliferation and Decrease Cisplatin Sensitivity in Ovarian Cancer Cells ENSG00000127483 ENSG00000143537 ENSG00000157110 ENSG00000163399 ENSG00000048392 ENSG00000291748 ENSG00000087460 ENSG00000168765 ENSG00000058673 PMC8601173__F1 Metabolic engineering of microorganisms for the production of multifunctional non‐protein amino acids: G‐aminobutyric acid and D‐aminolevulinic acid ENSG00000144410 ENSG00000122966 ENSG00000172005 ENSG00000150787 PMC9204890__F5 Genome-wide alternative splicing profile in the posterior kidney of brown trout (Salmo trutta) during proliferative kidney disease ENSG00000092871 ENSG00000080031 ENSG00000157741 ENSG00000116786 ENSG00000105251 ENSG00000162882 ENSG00000102893 ENSG00000072110 ENSG00000172936 ENSG00000198125 ENSG00000140416 PMC9643771__F1 Updates in combined approaches of radiotherapy and immune checkpoint inhibitors for the treatment of breast cancer ENSG00000183735 ENSG00000164430 PMC2930805__F1 Metabolic signaling pathway of candidate pathway ENSG00000169047 ENSG00000198793 PMC11519876__F1 Reelin signaling pathway in Alzheimer’s disease (AD) ENSG00000291971 ENSG00000173406 PMC7986695__F2 Crucial cells and molecules involved in postsynaptic responses in the regenerative niche at the vertebrate neuromuscular junction (NMJ) ENSG00000134569 ENSG00000149968 ENSG00000030304 PMC6447849__F1 Biogenesis of miRNA ENSG00000101751 ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC5468653__F3 Prolific nicotine production in the genus Nicotiana evolved from stepwise duplications of two primary metabolic pathways ENSG00000005381 PMC3729926__F6 Aldose Reductase Inhibition Enhances TRAIL-Induced Human Colon Cancer Cell Apoptosis through AKT/FOXO3a-dependent upregulation of Death Receptors ENSG00000171791 ENSG00000168040 PMC7280878__F4 Target genes and pathways of COL-3 and CGP-60474 in treating lung injury in COVID-19 ENSG00000102606 ENSG00000070831 ENSG00000205302 ENSG00000108518 ENSG00000089159 ENSG00000108691 ENSG00000224320 ENSG00000157227 ENSG00000149968 ENSG00000135446 ENSG00000177606 ENSG00000015285 ENSG00000105723 ENSG00000111642 ENSG00000026103 PMC9400233__F5 Two-stage genome-wide association study to identify novel genetic loci associated with acute radiotherapy toxicity in nasopharyngeal carcinoma ENSG00000088179 ENSG00000139725 ENSG00000115112 ENSG00000163083 ENSG00000096717 ENSG00000168610 ENSG00000136826 PMC5241319__F2 Autocrine and intracellular complement activation ENSG00000162711 ENSG00000125538 ENSG00000198793 ENSG00000117335 PMC4896923__F1 Involvement of Notch in the regulation of myelination and axonal growth ENSG00000117525 ENSG00000168214 ENSG00000148400 ENSG00000138798 ENSG00000198517 ENSG00000133961 ENSG00000137845 PMC4896923__F2 NRG/Erb signaling in the control of peripheral myelination and axonal growth ENSG00000198793 ENSG00000169783 ENSG00000112851 ENSG00000178568 ENSG00000109756 PMC5241319__F3 Systemic complement in metabolism ENSG00000042832 ENSG00000134830 ENSG00000182326 ENSG00000236625 PMC7917964__F10 Ingenuity Pathway Analysis ENSG00000245848 ENSG00000116044 ENSG00000172216 ENSG00000137033 ENSG00000177606 ENSG00000145777 ENSG00000136869 ENSG00000168610 ENSG00000106546 ENSG00000132170 PMC7606547__F4 Construction of a complete set of Neisseria meningitidis mutants and its use for the phenotypic profiling of this human pathogen ENSG00000122882 ENSG00000182511 ENSG00000196839 ENSG00000148798 ENSG00000087842 PMC2366099__F1 Folate and one-carbon metabolic pathway ENSG00000005421 ENSG00000124275 ENSG00000185339 ENSG00000116984 PMC4664912__F6 Transcriptomes reveal the genetic mechanisms underlying ionic regulatory adaptations to salt in the crab-eating frog ENSG00000064601 ENSG00000263014 ENSG00000126895 ENSG00000113790 ENSG00000163631 PMC4876452__F5 Identification of host genes leading to West Nile virus encephalitis in mice brain using RNA-seq analysis ENSG00000174125 ENSG00000167207 ENSG00000089127 ENSG00000172936 ENSG00000136869 ENSG00000135828 ENSG00000175104 ENSG00000106100 PMC4876452__F6 Identification of host genes leading to West Nile virus encephalitis in mice brain using RNA-seq analysis ENSG00000174123 ENSG00000162711 ENSG00000167207 ENSG00000174885 ENSG00000091106 ENSG00000106100 ENSG00000273992 ENSG00000226275 ENSG00000125538 ENSG00000281166 ENSG00000158077 ENSG00000142405 ENSG00000136869 ENSG00000185792 ENSG00000005381 ENSG00000184216 PMC4876452__F7 Identification of host genes leading to West Nile virus encephalitis in mice brain using RNA-seq analysis ENSG00000160789 ENSG00000102871 ENSG00000105939 ENSG00000138794 ENSG00000067900 ENSG00000168040 ENSG00000127191 ENSG00000111348 ENSG00000197694 ENSG00000148935 ENSG00000164305 ENSG00000178685 ENSG00000115317 ENSG00000160049 ENSG00000106683 ENSG00000100813 ENSG00000120868 ENSG00000064012 ENSG00000026103 PMC12058784__F3 Related biological functions in bone tissue ENSG00000189403 PMC9251379__F4 Molecular Mechanism of Yellow Mushroom (Floccularia luteovirens) Response to Strong Ultraviolet Radiation on the Qinghai-Tibet Plateau ENSG00000066926 ENSG00000172005 PMC10453365__F1 Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling ENSG00000177606 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC7662962__F2 Platelet activation by CXCR chemokine receptors ENSG00000169248 ENSG00000161921 ENSG00000121966 PMC1867370__F9 Root Phenotypes of Wild-Type, noxy2, and coi1-1 Plants Responding to Oxylipins.Ten-day-old seedlings grown on MS medium and in the presence of 9-HOT (25 μM), 9-oxo-C9 (15 μM), or JA (10 μM) PMC3531730__F6 Proposed model for the signaling pathway mediating NFKB activation induced by C-type lectin receptors ENSG00000187796 ENSG00000197943 ENSG00000175104 PMC3183592__F1 Normal hepatic methionine metabolism ENSG00000173599 ENSG00000133027 PMC5347794__F9 Bisdemethoxycurcumin exerts pro-apoptotic effects in human pancreatic adenocarcinoma cells through mitochondrial dysfunction and a GRP78-dependent pathway ENSG00000144895 ENSG00000164949 PMC9355550__F2 Combinatorial Strategies With PD-1/PD-L1 Immune Checkpoint Blockade for Breast Cancer Therapy: Mechanisms and Clinical Outcomes ENSG00000134982 PMC5272919__F2 Opportunistic intruders: how viruses orchestrate ER functions to infect cells ENSG00000104969 ENSG00000164031 ENSG00000170464 ENSG00000148719 PMC10384840__F9 Natural Flavonoids Quercetin and Kaempferol Targeting G2/M Cell Cycle-Related Genes and Synergize with Smac Mimetic LCL-161 to Induce Necroptosis in Cholangiocarcinoma Cells ENSG00000137275 ENSG00000102871 ENSG00000166278 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC4112617__F1 Insulin-like growth factor pathway ENSG00000197081 ENSG00000140443 PMC9266441__F2 Pharmacological Effects of Polyphenol Phytochemicals on the Intestinal Inflammation via Targeting TLR4/NFKB Signaling Pathway ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC6399612__F9 Myogenin promoter‐associated lncRNA Myoparr is essential for myogenic differentiation ENSG00000101751 PMC9657829__F6 DNA Methylation in Neurological Diseases ENSG00000156110 ENSG00000189056 ENSG00000204406 PMC6164146__F2 Activation and Attenuation of IL-33/ST2 Signaling ENSG00000137033 ENSG00000172936 ENSG00000185187 ENSG00000175104 ENSG00000184216 PMC9657829__F4 DNA Methylation in Neurological Diseases ENSG00000012048 ENSG00000142192 PMC7778457__F2 FA signaling in the DNA ICL repair pathway ENSG00000136492 ENSG00000083093 ENSG00000077152 ENSG00000188827 ENSG00000187790 ENSG00000168411 ENSG00000139618 ENSG00000276043 ENSG00000131944 ENSG00000012048 ENSG00000175054 ENSG00000127445 ENSG00000144554 ENSG00000108384 ENSG00000051180 PMC6100577__F3 Double strand break chromatin stability mechanisms ENSG00000143799 ENSG00000149311 ENSG00000105486 ENSG00000163961 ENSG00000291803 ENSG00000197299 ENSG00000112130 PMC8528729__AF1 MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer ENSG00000139352 ENSG00000137709 PMC10960969__F8 Metabolic pathway of methanotrophs ENSG00000179091 ENSG00000105953 ENSG00000119912 ENSG00000062485 ENSG00000134531 PMC3037747__F4 BCR, NFKB, and PI3K/AKT/mTOR deregulation in MCL ENSG00000095585 ENSG00000104856 ENSG00000186716 ENSG00000173039 ENSG00000185104 PMC12052849__F5 Proposed working model of apoptosis regulated by USP18 through the PERK-eIF2Alpha-ATF4 signaling pathway ENSG00000184979 ENSG00000128272 PMC7804490__F2 T cell signaling by E3 ligases and DUBs ENSG00000135655 ENSG00000291603 ENSG00000213658 ENSG00000070831 ENSG00000150907 ENSG00000083799 PMC10545718__F1 Bioactive lipid-mediated regulation of insulin downstream signaling and lipid metabolism in adipocytes: mechanistic overview ENSG00000135218 ENSG00000042832 ENSG00000095321 ENSG00000169047 PMC4607871__F2 Spindle assembly checkpoint and error correction ENSG00000171444 ENSG00000134982 ENSG00000117399 PMC10545718__F2 Genetic deletion of lipid biosynthetic and metabolic enzymes on adipocyte metabolism ENSG00000135218 ENSG00000042832 ENSG00000172057 ENSG00000151117 PMC9396482__F1 Wnt/Beta-catenin signaling: a multifunctional target for neuroprotective and regenerative strategies in Parkinson’s disease ENSG00000134982 ENSG00000173786 ENSG00000125084 PMC5765398__F2 Mucosal tolerance in the gut and its breakdown in food allergy ENSG00000168329 ENSG00000140968 ENSG00000203710 ENSG00000137265 ENSG00000107485 ENSG00000291905 PMC5969551__F2 Role of Cic in Ras-MAPK signaling and growth control ENSG00000197905 ENSG00000079432 ENSG00000007866 ENSG00000150457 ENSG00000074219 PMC5902686__F7 Putative metabolic pathway of drought stress responses in flag leaves and developing grains of Zhongmai 175 ENSG00000159224 ENSG00000197429 PMC3037747__F2 Cyclin D1, at the center of MCL pathogenesis ENSG00000149311 ENSG00000135446 ENSG00000167513 ENSG00000198793 ENSG00000123374 ENSG00000105810 PMC7290580__F3 Signaling pathways by cIAP-mediated degradation of TRAF2 and/or TRAF3 ENSG00000056558 ENSG00000172936 ENSG00000162924 ENSG00000131323 ENSG00000127191 PMC6424867__F6 Arenaviral proteins (NP and Z) inhibit the RIG-I/MDA5 and NFKB pathways ENSG00000088888 ENSG00000172005 ENSG00000172936 ENSG00000276561 ENSG00000184216 PMC6392423__F8 Protein kinase C pathway for prolactin regulation of metabolic gene expression in prostate epithelial cells as represented by mitochondrial aspartate aminotransferase ENSG00000177606 PMC6287621__F1 Specific targets and potential therapeutic strategies to inhibit or slow the progression of CKD ENSG00000019991 ENSG00000086991 PMC12041846__F6D DEGs from GSE49028 dataset of binge ethanol-treated mice on signaling pathways related to anxiety and locomotor activity ENSG00000144596 ENSG00000100151 ENSG00000155974 ENSG00000196586 PMC8257731__F1 Detailed drawing of the fine molecular mechanisms of lithium on specific cell targets ENSG00000111537 ENSG00000198793 ENSG00000100219 ENSG00000168610 PMC11076692__F2 46,XX Testicular and ovotesticular DSD ENSG00000162552 ENSG00000169218 ENSG00000066468 ENSG00000125398 ENSG00000137090 ENSG00000005513 ENSG00000168036 ENSG00000134595 ENSG00000102678 ENSG00000100146 PMC11076692__F1 Genes and mechanisms of sex determination ENSG00000066468 ENSG00000143355 ENSG00000173894 ENSG00000170370 ENSG00000125398 ENSG00000137090 ENSG00000285109 ENSG00000168036 ENSG00000102678 ENSG00000100146 PMC2417187__F7 Activation of the UPR in the absence of H6PD ENSG00000128272 ENSG00000100219 PMC7695361__F7 Mechanism diagram of the KEGG pathway ENSG00000281324 ENSG00000162337 ENSG00000173039 ENSG00000099860 ENSG00000205250 ENSG00000118971 ENSG00000095739 ENSG00000135446 ENSG00000125538 ENSG00000164483 ENSG00000056558 ENSG00000105810 ENSG00000162692 ENSG00000080839 PMC6539093__F2 Schematic view of the ERK pathway in response to growth factors, hormones, and mechanical stress ENSG00000112851 ENSG00000022267 ENSG00000108061 PMC7460641__F3A Oxidant-Induced Alterations in the Adipocyte Transcriptome: Role of the Na,K-ATPase Oxidant Amplification Loop ENSG00000090402 ENSG00000002330 ENSG00000069482 ENSG00000256762 ENSG00000038002 PMC4272446__F2 NOD1 and NOD2: Signaling, Host Defense, and Inflammatory Disease ENSG00000023445 ENSG00000284881 ENSG00000110330 ENSG00000167207 ENSG00000100906 ENSG00000269335 ENSG00000173039 ENSG00000154124 ENSG00000118503 ENSG00000078747 ENSG00000177606 ENSG00000169429 ENSG00000157625 PMC4005353__F1 AGS genes cooperate to metabolize reverse transcription products of endogenous retroelements ENSG00000183735 PMC3426484__F1 Asparagine N-Glycosylation pathway ENSG00000116406 ENSG00000172469 ENSG00000131446 ENSG00000172269 ENSG00000033011 ENSG00000284501 ENSG00000167130 ENSG00000128268 ENSG00000135506 ENSG00000198162 ENSG00000173540 ENSG00000086848 ENSG00000196547 ENSG00000168282 ENSG00000119523 ENSG00000163933 ENSG00000214160 ENSG00000111885 ENSG00000136908 ENSG00000100417 ENSG00000112893 ENSG00000089597 ENSG00000013375 ENSG00000101901 ENSG00000253710 ENSG00000139133 ENSG00000148488 ENSG00000088035 ENSG00000182858 PMC8687818__F5 Anticancer Action of Xiaoxianxiong Tang in Non-Small Cell Lung Cancer by Pharmacological Analysis and Experimental Validation ENSG00000108691 ENSG00000171105 ENSG00000138798 ENSG00000177606 ENSG00000136997 ENSG00000173039 ENSG00000123374 ENSG00000007908 ENSG00000171791 ENSG00000146648 ENSG00000164305 ENSG00000007171 PMC8973075__F3 Mesenchymal Stromal Cells for Enhancing Hematopoietic Engraftment and Treatment of Graft-Versus-Host Disease, Hemorrhages and Acute Respiratory Distress Syndrome ENSG00000178860 ENSG00000003436 ENSG00000196352 ENSG00000117335 PMC12128733__F8 Hypothetic molecular mechanisms and modes of the pharmacological action of adaptogen are updated from the authors’ free access publication [66] and authors’ drawings PMC8687818__F8 Anticancer Action of Xiaoxianxiong Tang in Non-Small Cell Lung Cancer by Pharmacological Analysis and Experimental Validation ENSG00000132906 ENSG00000138798 ENSG00000177606 ENSG00000136997 ENSG00000173039 ENSG00000123374 ENSG00000145386 ENSG00000164305 PMC7383626__F1 Non–small cell lung cancer tumorigenesis pathways and mutation frequencies are illustrated ENSG00000157764 ENSG00000047936 ENSG00000121879 ENSG00000146648 ENSG00000196712 PMC12128733__F9 Effect of Rhodiola extracts on the eicosanoid signaling pathway ENSG00000108839 ENSG00000161905 ENSG00000160013 ENSG00000111321 PMC5320608__F10 Schematic model of TREM2 in the regulation of Beta-catenin signaling and microglial survival ENSG00000154342 ENSG00000168036 PMC8268497__F6 Small Molecules and Their Effect on the Molecular Mechanisms of Early Retinal Organoid Development ENSG00000168214 ENSG00000137845 ENSG00000101752 PMC11502356__F6 Insulin signaling pathway and the shortlisted key mRNA markers ENSG00000149311 ENSG00000291971 ENSG00000150907 ENSG00000198793 ENSG00000136997 ENSG00000137265 ENSG00000136869 ENSG00000171791 ENSG00000168610 PMC4599573__F13 Schematic diagram shows that PLB regulates the Nrf2-mediated oxidative signaling pathway and its downstream proteins NQO1, GST, and HSP90 in SCC25 cells.Abbreviations: ROS, reactive oxygen species; GST, glutathione S-transferase ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC3989738__F6 Direct target genes of hypoxia-mediated hypoxia-inducible factor-1A (HIF-1A) signaling ENSG00000059804 ENSG00000112715 PMC7936035__F7 Not Frozen in the Ice: Large and Dynamic Rearrangements in the Mitochondrial Genomes of the Antarctic Fish PMC4636767__F5 Schematic presentation of a model highlighting the probable mode of action of AMA on placental development ENSG00000169245 ENSG00000134460 ENSG00000108691 PMC9540681__F2 Human–rat integrated microRNAs profiling identified a new neonatal cerebral hypoxic–ischemic pathway melatonin‐sensitive ENSG00000169291 ENSG00000135446 ENSG00000138798 ENSG00000198793 ENSG00000105810 PMC3156782__F2 Wnt/Beta-catenin signaling pathway generated by Ingenuity Pathway Analysis (IPA) ENSG00000087095 ENSG00000156076 ENSG00000136997 ENSG00000026508 ENSG00000168646 ENSG00000196628 PMC8243607__F6 Transcriptomics identifies key defense mechanisms in rice resistant to both leaf-feeding and phloem feeding herbivores ENSG00000105722 PMC6043822__F6 The main modulated genes and their reciprocal interactions in the cell ENSG00000162552 ENSG00000111057 ENSG00000106333 ENSG00000105329 ENSG00000117519 ENSG00000162551 ENSG00000125384 ENSG00000145386 ENSG00000137801 ENSG00000072571 ENSG00000159200 ENSG00000139289 ENSG00000163710 ENSG00000162692 ENSG00000123689 ENSG00000136068 PMC6559886__F5 Fistein Suppresses Human Osteosarcoma U-2 OS Cell Migration and Invasion via Affecting FAK, uPA and NF-ĸB Signaling Pathway In Vitro ENSG00000168036 ENSG00000146648 PMC8139523__F2 Take a Walk to the Wild Side of Caenorhabditis elegans-Pathogen Interactions ENSG00000118515 PMC7268632__F2 Endoplasmic Reticulum (ER) Proteostasis Network ENSG00000100220 ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC12004596__F1 Inhibition of T‐cell activation ENSG00000291603 ENSG00000134982 ENSG00000104760 ENSG00000189403 PMC7268632__F3 Novel Outputs of the Unfolded Protein Response (UPR) Related to Learning and Memory Processes ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8509383__F2 Melatonin as a Therapeutic Agent for the Inhibition of Hypoxia-Induced Tumor Progression: A Description of Possible Mechanisms Involved ENSG00000109861 ENSG00000187764 ENSG00000171791 ENSG00000154188 PMC8901478__F2 Talimogene Laherparepvec: Moving From First-In-Class to Best-In-Class ENSG00000164430 ENSG00000105397 ENSG00000127948 PMC5455318__F2 Hyperinsulinemia on the tumor cell microenvironment and intracellular signaling that contribute to tumor growth and progression ENSG00000169047 ENSG00000140443 PMC6122270__F4 Multiple pathways of CD44/CD44v6-promoted CIC motility: CD44/CD44v6 drive CIC motility by activation of signaling cascades as well as protease activation ENSG00000281324 ENSG00000168036 ENSG00000137845 ENSG00000168610 ENSG00000146648 ENSG00000121966 ENSG00000164949 PMC4633447__F4 Schematic diagram showing the possible consequences of SLC7A3 dysfunction on the mTOR and NO pathways ENSG00000177169 ENSG00000198793 ENSG00000155792 ENSG00000167965 PMC5110160__F10 Acute Simian Varicella Virus Infection Causes Robust and Sustained Changes in Gene Expression in the Sensory Ganglia ENSG00000140992 ENSG00000067836 ENSG00000284774 ENSG00000131165 ENSG00000105290 ENSG00000108819 ENSG00000181409 ENSG00000100146 ENSG00000197063 ENSG00000130706 ENSG00000169291 ENSG00000121068 ENSG00000169750 ENSG00000197971 ENSG00000291387 ENSG00000077782 ENSG00000101265 ENSG00000284161 ENSG00000131095 ENSG00000105698 ENSG00000063245 ENSG00000136960 ENSG00000165478 ENSG00000198728 ENSG00000130175 ENSG00000163517 ENSG00000198911 PMC8506063__F7 Bioinformatics analysis reveals the roles of cytoskeleton protein transgelin in occurrence and development of proteinuria ENSG00000002330 ENSG00000105401 ENSG00000169047 ENSG00000165269 ENSG00000173391 ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000065833 ENSG00000150991 ENSG00000186716 ENSG00000136997 ENSG00000100979 PMC6122270__F3 CD44/CD44v6 and CIC apoptosis resistance ENSG00000019991 ENSG00000137673 ENSG00000213658 ENSG00000105401 ENSG00000113070 ENSG00000173599 ENSG00000100985 ENSG00000164305 ENSG00000178568 ENSG00000026103 PMC6085123__F5 NOD-like receptor signaling pathway ENSG00000150782 ENSG00000187796 ENSG00000105397 ENSG00000115415 ENSG00000163568 ENSG00000136869 ENSG00000265972 ENSG00000064012 PMC2818233__F2 Nuclear phosphoinositide-mediated stress response pathway ENSG00000100387 ENSG00000139515 ENSG00000121067 PMC7494507__F2 Regulatory mechanisms of CD47 expression.Regulators of CD47 expression in cancer cells includes cytokines, oncogenes, microRNAs as well as enzymes ENSG00000198053 ENSG00000136997 ENSG00000011478 ENSG00000168610 PMC7283076__F1 Cytokine storm induced by SARS-CoV-2 ENSG00000163464 ENSG00000150782 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000168610 PMC2323406__F4 Stimulus Design for Model Selection and Validation in Cell Signaling ENSG00000138798 ENSG00000146648 PMC7283076__F2 TLR recognizes extracellular PAMPs and initiates the transcription of NLRP3, proIL-1B, and proIL-18 through the NFKB signaling pathway, and oligomerized NLRP3, ASC and pro-caspase-1 form a multiprotein complex that activates caspase-1 ENSG00000162711 ENSG00000125538 ENSG00000189403 PMC4155598__F8 CDK 4/6 inhibitors sensitize PIK3CA Mutant Breast Cancer to PI3K inhibitors ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC8113420__F1 Possible mechanistic links between the activation of the PKR-eIF2A branch of the ISR and hippocampal/cortical plasticity under physiological and age-related neurodegenerative conditions ENSG00000134438 ENSG00000128272 ENSG00000144895 PMC5485424__F9 Schematic model of BRAFV600E signaling-induced epigenetic silencing by H3K27me3 in tumorigenesis ENSG00000108799 ENSG00000145321 ENSG00000139154 ENSG00000074266 ENSG00000178691 ENSG00000113360 ENSG00000008083 PMC8459449__F1 Pancreatic ß-cell Response to Secretory Demands and Adaption to Stress ENSG00000079387 ENSG00000084093 ENSG00000126266 PMC8634673__F1 Epstein-Barr Virus and the Origin of Myalgic Encephalomyelitis or Chronic Fatigue Syndrome ENSG00000111537 ENSG00000179344 ENSG00000049768 ENSG00000115009 PMC8429127__F1 Sulforaphane-Nrf2-GSTM1 pathway in the prevention of kidney disease progression: Gene - diet interaction ENSG00000181019 ENSG00000187134 ENSG00000079999 PMC6717205__F1 Schematic overview of glycolysis and mitochondrial respiration ENSG00000180210 PMC3748992__F5 Quantitative Proteomics Identifies Activation of Hallmark Pathways of Cancer in Patient Melanoma ENSG00000172380 ENSG00000169750 ENSG00000178363 ENSG00000080166 ENSG00000107165 PMC9131252__F1 Electrical charge on ferroelectric nanocomposite membranes enhances SHED neural differentiation ENSG00000198793 ENSG00000178568 PMC3835203__F1 New mechanisms of NOD-like receptor-associated inflammasome activation ENSG00000154451 ENSG00000162711 ENSG00000185515 ENSG00000088888 ENSG00000136869 PMC5732032__F1 Targeting EGFR Co-dependent Signaling Pathways in Glioblastoma ENSG00000291971 ENSG00000198793 ENSG00000146648 PMC5286880__F5 Interferon signaling pathway as differentially regulated by ZIKV and HCMV in maternal-decidual and fetus-derived chorionic villus tissues ENSG00000068079 ENSG00000111537 ENSG00000105397 ENSG00000185201 ENSG00000185885 PMC2981097__F2 Double strand DNA repair: Homologous recombination and Non-homologous end joining ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000136492 ENSG00000083093 ENSG00000164754 ENSG00000051180 ENSG00000256683 ENSG00000139618 PMC5732032__F4 Targeting EGFR Co-dependent Signaling Pathways in Glioblastoma ENSG00000141867 ENSG00000125398 ENSG00000130164 ENSG00000176165 PMC8088128__F3 Leucine-Rich Repeat Protein Provides a SHOC2 the RAS Circuit: a Structure-Function Perspective ENSG00000112851 ENSG00000165280 ENSG00000141564 ENSG00000121879 ENSG00000086758 ENSG00000108061 ENSG00000109670 PMC8980014__F1 CSNK2 phosphotargets, associated pathways, and CSNK2-regulated phenotypes identified in this review ENSG00000104365 ENSG00000100906 ENSG00000198793 ENSG00000269335 ENSG00000173039 ENSG00000213341 ENSG00000168610 ENSG00000146648 PMC9457836__F5 Betuletol, a Propolis Component, Suppresses IL-33 Gene Expression and Effective against Eosinophilia ENSG00000137033 ENSG00000172936 ENSG00000113525 ENSG00000184216 PMC8424196__F4 Functions and Molecular Mechanisms of Deltex Family Ubiquitin E3 Ligases in Development and Disease ENSG00000143799 ENSG00000169245 ENSG00000163840 ENSG00000178498 ENSG00000125347 ENSG00000137845 ENSG00000135144 ENSG00000165819 ENSG00000110042 ENSG00000168118 PMC10417792__F1 The MET signaling pathway and the sites of action for MET targeted therapies ENSG00000019991 ENSG00000291971 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC2749725__F1 Coverage of the insulin receptor signaling pathway ENSG00000099330 ENSG00000002330 ENSG00000095321 ENSG00000106070 ENSG00000198793 ENSG00000102104 PMC3253327__F1 Acute and Chronic Regulation of Aldosterone Production ENSG00000203859 ENSG00000179142 PMC3253327__F2 Acute and Chronic Regulation of Aldosterone Production ENSG00000185231 ENSG00000173599 PMC8424196__F3 Functions and Molecular Mechanisms of Deltex Family Ubiquitin E3 Ligases in Development and Disease ENSG00000143799 ENSG00000183735 ENSG00000163840 ENSG00000049768 ENSG00000135144 ENSG00000110042 ENSG00000091073 PMC8088128__F5 Leucine-Rich Repeat Protein Provides a SHOC2 the RAS Circuit: a Structure-Function Perspective ENSG00000157764 ENSG00000108061 PMC7361619__F1 COVID‐19—Associated dyslipidemia: Implications for mechanism of impaired resolution and novel therapeutic approaches ENSG00000130164 ENSG00000005421 ENSG00000130234 ENSG00000160179 ENSG00000135517 PMC8124226__F7 Microencapsulated Bifidobacterium bifidum and Lactobacillus gasseri in Combination with Quercetin Inhibit Colorectal Cancer Development in ApcMin/+ Mice ENSG00000138795 ENSG00000134982 ENSG00000165879 ENSG00000168036 ENSG00000107829 PMC8948217__F3 Notch signaling pathway: architecture, disease, and therapeutics ENSG00000125398 ENSG00000135100 PMC8948217__F5 Notch signaling pathway: architecture, disease, and therapeutics ENSG00000108691 ENSG00000107485 ENSG00000049768 PMC4988489__F2 The piRNA Pathway: Guardian of the Genome –A Fly’s Perspective ENSG00000065833 ENSG00000038002 PMC8802807__F12 Disruption of Epidermal Growth Factor Receptor but Not EGF Blocks Follicle Activation in Zebrafish Ovary ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000146648 PMC7350315__F3 Schematic overview of the classical ATM and ATR DDR ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000276618 ENSG00000144554 PMC7350315__F4 ATR signaling pathway is involved in the HPV life cycle ENSG00000175054 ENSG00000144554 ENSG00000285109 ENSG00000171848 PMC3696796__F5 Schematic depiction of LB-205 effects on NGF stimulated pathways ENSG00000120868 PMC7822850__F8 LINC01152 upregulates MAML2 expression to modulate the progression of glioblastoma multiforme via Notch signaling pathway ENSG00000168214 ENSG00000184384 PMC9358040__F4 Dysregulation of Subcutaneous White Adipose Tissue Inflammatory Environment Modelling in Non-Insulin Resistant Obesity and Responses to Omega-3 Fatty Acids – A Double Blind, Randomised Clinical Trial ENSG00000281324 ENSG00000137673 ENSG00000140262 ENSG00000105329 ENSG00000134982 ENSG00000291971 ENSG00000168036 ENSG00000106483 ENSG00000277641 ENSG00000163792 ENSG00000164488 ENSG00000157240 ENSG00000071564 ENSG00000163251 ENSG00000115266 ENSG00000026508 PMC6275040__F1 Schematic representation summarizing the transforming growth factors-beta (TGFB) receptor complexes and signaling pathway in endothelial cells ENSG00000170365 ENSG00000198732 PMC5299619__F1 The canonical T2R signaling pathway ENSG00000185933 ENSG00000070985 ENSG00000137841 PMC8969576__F3 Targeting Chitinase 1 and Chitinase 3-Like 1 as Novel Therapeutic Strategy of Pulmonary Fibrosis ENSG00000108691 ENSG00000133048 ENSG00000133063 ENSG00000026508 PMC7352656__F1 Molecular mechanisms for acquired resistance ENSG00000167601 ENSG00000019991 ENSG00000138798 ENSG00000198793 ENSG00000168610 ENSG00000146648 ENSG00000140443 PMC6148305__F12 Hypothetical pathway of MIF-2/D-DT-dependent mechanisms in proximal tubule cell regeneration ENSG00000019582 ENSG00000128272 ENSG00000144895 ENSG00000026508 ENSG00000124107 PMC7880315__F8 Working model of Beta-elemene and RT on tumor growth in NSCLC cells ENSG00000170558 ENSG00000026508 PMC3468386__F1 The canonical Wnt signaling pathway ENSG00000134982 PMC2675709__F5 Comparison of metabolites and transcripts in glycolysis, tricarboxylic acid (TCA) cycle, and pH-regulating pathways between the wild type (WT) and the stop1 mutant ENSG00000065833 ENSG00000082212 PMC7071121__F6 Proposed mechanism for RPG in regulating the uterine involution in post-natal dairy cows ENSG00000197081 ENSG00000198793 ENSG00000140443 PMC7261103__F2 Role of renin/angiotensin system (RAS) and kallikrein/kinin system (KKS) in pathogenesis of COVID-19 ENSG00000130234 ENSG00000184012 ENSG00000122194 PMC8277969__F3 Metabolic reprogramming in cancer: mechanistic insights from Drosophila ENSG00000147162 ENSG00000136997 ENSG00000146648 PMC4369962__F4 Calcium signaling pathway in old nitrate treated aorta ENSG00000182533 ENSG00000041982 ENSG00000156026 ENSG00000186716 PMC7412701__F6 Schematic diagram and potential mechanisms of sotrastaurin inhibition effect on osteoclast resorption ENSG00000164935 ENSG00000102575 ENSG00000143387 PMC11262449__F1 Genes involved in glucose sensing, the reward system, sweet taste receptors, the endocannabinoid system, and insulin mediated glucose uptake found to have SNP associations with dietary sugar intake and/or cardiometabolic risk factors in children ENSG00000171105 ENSG00000169047 PMC8229527__F1 NKG2D Natural Killer Cell Receptor—A Short Description and Potential Clinical Applications ENSG00000112977 ENSG00000197943 ENSG00000141968 PMC9352970__F2 Cardiovascular protection by SGLT2 inhibitors – Do anti-inflammatory mechanisms play a role? ENSG00000162711 ENSG00000198793 ENSG00000162692 PMC7141637__F1 Proposed model for SARS-CoV-2-associated diarrhea ENSG00000130234 ENSG00000198793 ENSG00000184012 PMC7767049__F2 Administration of Beta-AR blockade can enhance the efficacy of RT by modulation of tumor microenvironment in irradiated and non-irradiated tumors ENSG00000169245 ENSG00000186810 ENSG00000111537 ENSG00000138755 ENSG00000159399 PMC4865030__F1 Interplay between Fanconi anemia and homologous recombination pathways in genome integrity ENSG00000136492 ENSG00000083093 ENSG00000138346 ENSG00000178295 ENSG00000077152 ENSG00000188827 ENSG00000139618 ENSG00000131944 ENSG00000012048 ENSG00000175054 ENSG00000165392 ENSG00000108384 ENSG00000197299 ENSG00000051180 ENSG00000276787 PMC6478283__F13 Identification of key regulatory genes connected to NFKB family of proteins in visceral adipose tissues using gene expression and weighted protein interaction network ENSG00000104856 ENSG00000002330 ENSG00000109320 ENSG00000130522 ENSG00000138798 ENSG00000162924 ENSG00000171791 ENSG00000187266 ENSG00000125879 ENSG00000149311 ENSG00000066468 ENSG00000138378 ENSG00000077150 ENSG00000115415 ENSG00000177606 ENSG00000136869 ENSG00000198670 ENSG00000175104 ENSG00000162692 ENSG00000146648 ENSG00000132341 PMC4683444__F5 Using activation status of signaling pathways as mechanism-based biomarkers to predict drug sensitivity ENSG00000157404 ENSG00000049130 ENSG00000109320 ENSG00000102871 ENSG00000169047 ENSG00000115138 ENSG00000080166 ENSG00000213341 ENSG00000169032 ENSG00000127191 ENSG00000168610 PMC12193766__F3 Marine-Derived Astaxanthin: Molecular Mechanisms, Biomedical Applications, and Roles in Stem Cell Biology ENSG00000178573 ENSG00000079999 PMC5622249__F6 Schematic diagram of hypothetical mechanisms underlying chloroquine enhances sensitivity to cisplatin in ovarian cancer cells ENSG00000198793 ENSG00000057663 PMC5857537__F2 Molecular alterations in aldosterone-producing benign adrenal cortical neoplasms ENSG00000067842 ENSG00000179142 PMC5386520__F2 Gas6 and TAM receptor signalling ENSG00000167601 ENSG00000092445 ENSG00000002330 ENSG00000071051 ENSG00000168610 PMC11700734__F11 Metabolomic and metagenomic analyses elucidate the role of intercropping in mitigating continuous cropping challenges in tobacco ENSG00000107331 ENSG00000197872 ENSG00000205221 ENSG00000166402 ENSG00000173599 ENSG00000198576 ENSG00000138119 ENSG00000118777 ENSG00000170571 PMC8399382__F1 Metabolic Host–Microbiota Interactions in Autophagy and the Pathogenesis of Inflammatory Bowel Disease (IBD) ENSG00000167207 ENSG00000237693 ENSG00000145782 ENSG00000057663 PMC4729697__F7 Ingenuity Pathway Analysis (IPA) illustration showing upstream regulation of the pathway for NFKB ENSG00000150782 ENSG00000171720 PMC5857537__F7 Molecular alterations in cortisol-producing benign adrenal cortical neoplasms ENSG00000185231 PMC4743890__F1 Neural circuitry and immunity ENSG00000087085 ENSG00000136869 PMC8945726__F2 Mitochondrial Oxidative Stress and Cell Death in Podocytopathies ENSG00000132906 ENSG00000171791 ENSG00000064012 PMC3461213__F1 Regulatory mechanisms of phosphate homeostasis ENSG00000118972 ENSG00000152266 ENSG00000152592 PMC3156300__F9 Prolactin-Stimulated Activation of ERK1/2 Mitogen-Activated Protein Kinases is Controlled by PI3-Kinase/Rac/PAK Signaling Pathway in Breast Cancer Cells ENSG00000113494 PMC8600311__F2 Host Sex Steroids Interact With Virus Infection: New Insights Into Sex Disparity in Infectious Diseases ENSG00000142627 ENSG00000163914 ENSG00000196154 PMC4865030__F2 Interplay between Fanconi anemia and homologous recombination pathways in genome integrity ENSG00000131944 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000077152 ENSG00000051180 ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000166508 ENSG00000139618 PMC8470500__F1 Gold Nanoparticles: Multifaceted Roles in the Management of Autoimmune Disorders ENSG00000125538 PMC8470500__F2 Gold Nanoparticles: Multifaceted Roles in the Management of Autoimmune Disorders ENSG00000162711 ENSG00000136869 ENSG00000132693 ENSG00000135517 PMC7283441__F1 Signaling cascade of apoptosis in traumatic brain injury (TBI) ENSG00000002330 ENSG00000026103 PMC7762483__F5 Oxidative stress-induced activation of AP-1 in an ASK1-dependent manner induces TGFB and galectin-9 expression ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000010671 PMC6873206__F1 YAP regulation by mechanical stimuli ENSG00000150457 ENSG00000131023 PMC9558365__F1 Wnt/Beta-catenin signalling pathway in Haematological Neoplasms ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9577372__F2 Transforming growth factorB in tumour development ENSG00000176692 ENSG00000169554 ENSG00000070831 ENSG00000122691 ENSG00000129514 ENSG00000175104 PMC8473795__F3 Glycocalyx Impairment in Vascular Disease: Focus on Inflammation ENSG00000162711 ENSG00000125538 ENSG00000172936 ENSG00000162692 PMC3595616__F1 The branched isoprenoid pathway ENSG00000172893 ENSG00000197429 ENSG00000174197 PMC3461213__F4 Overall picture of the physiology of FGF-23 and its role in phosphate homeostasis ENSG00000118972 ENSG00000152266 ENSG00000152592 PMC7826455__F6 Role of miR‐362 in cervical cancer PMC2892459__F5 Overlay of IfnB timecourse analysis onto the macrophage pathway using BioLayout Express3D ENSG00000117228 ENSG00000145365 ENSG00000027697 ENSG00000171791 ENSG00000125347 ENSG00000276561 ENSG00000169245 ENSG00000115415 ENSG00000138755 ENSG00000164136 ENSG00000172936 ENSG00000168310 ENSG00000026103 ENSG00000164342 PMC2518081__F3 The pathways involved in polycystic kidney disease ENSG00000173599 ENSG00000001626 PMC9577372__F7 Transforming growth factorB in tumour development ENSG00000087245 ENSG00000100985 PMC2892459__F4 Snapshots from the integrated macrophage pathway diagram ENSG00000171855 ENSG00000181788 ENSG00000103035 ENSG00000153827 ENSG00000142166 ENSG00000187566 ENSG00000180228 ENSG00000105397 ENSG00000185627 ENSG00000175166 ENSG00000159352 ENSG00000277263 ENSG00000108671 ENSG00000173692 ENSG00000159399 ENSG00000026103 PMC9201061__F2 Clinical Manifestations and Molecular Backgrounds of Parkinson's Disease Regarding Genes Identified From Familial and Population Studies ENSG00000129003 PMC5228322__F1 Illustration of the Wnt signaling pathways ENSG00000087095 ENSG00000163914 ENSG00000168036 PMC7408457__F2 Change in the profile of proteins and mRNAs of molecular factors in the primary tumor of the kidney and its metastatic sites ENSG00000198793 PMC5996030__F2 Possible autophagy signaling pathways in traumatic brain injury (TBI) ENSG00000181019 ENSG00000198793 ENSG00000136869 PMC5858516__F9 HyFS and the Hsp90/Akt/mTOR axis in lung cancer cells ENSG00000177169 ENSG00000123395 ENSG00000198793 PMC7819896__F1 Cartoon representing the overview of the pathogenesis of COVID-19 and the potential activity of ruxolitinib ENSG00000105639 PMC9931120__F11 The working model of how FMDV infection regulates host amino acid metabolism ENSG00000166558 ENSG00000198793 PMC2813054__F1 Changes in Akt signaling with differentiation of CD8+ T cells and co-inhibitory receptor killer-cell lectin like receptor G1 (KLRG1)-blocked highly differentiated CD8+ T cells ENSG00000139187 PMC8094964__F10 DDIT3 Targets Innate Immunity via the DDIT3-OTUD1-MAVS Pathway To Promote Bovine Viral Diarrhea Virus Replication ENSG00000088888 ENSG00000165312 ENSG00000198742 ENSG00000157601 PMC3760546__F4 Atherosclerosis, platelets and thrombosis in acute ischaemic heart disease ENSG00000003436 ENSG00000122194 PMC7921671__F3 Cysteine metabolic circuitries: druggable targets in cancer ENSG00000173156 ENSG00000062485 PMC3760546__F6 Natural inhibitors of coagulation and anticoagulant drugs.TF, tissue factor; VKA, vitamin K antagonists; AT, antithrombin; APC, activated protein C; TFPI, tissue factor pathway inhibitor type-1 ENSG00000180210 ENSG00000134982 PMC5346233__F2 Targeting Notch signalling pathway regulates angiogenesis in the pathological ovary ENSG00000148400 ENSG00000074181 PMC3533361__F1 GSK3 signaling in neural development ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000134982 PMC7921671__F5 Cysteine metabolic circuitries: druggable targets in cancer ENSG00000079432 ENSG00000116761 PMC7572318__F3 RIPLET is an essential E3 ligase for RIG-I signaling pathway ENSG00000183735 ENSG00000088888 PMC9144507__F2 Metformin and Cancer, an Ambiguanidous Relationship ENSG00000198793 ENSG00000140443 PMC7402324__F2 WNT Signaling in Melanoma ENSG00000169071 ENSG00000070831 ENSG00000163914 PMC11379076__F2 MTORC1/2 signaling pathways ENSG00000177169 ENSG00000083290 ENSG00000155792 ENSG00000167965 PMC7402324__F3 Proposed model of the crosstalk between canonical and non-canonical WNT-signaling in melanoma ENSG00000281324 ENSG00000169071 ENSG00000181788 ENSG00000162337 ENSG00000170558 ENSG00000026508 ENSG00000168036 ENSG00000165527 PMC11379076__F3 Interaction between mTOR pathway and HCC ENSG00000100811 ENSG00000131473 ENSG00000177169 ENSG00000136997 ENSG00000081051 ENSG00000121966 PMC7590211__F3 Opposing modulatory effects of TRIM25 and TRIM47 on TGFBeta-Smad signaling in the GI tract ENSG00000166326 ENSG00000106785 ENSG00000198793 ENSG00000132481 ENSG00000121060 PMC3942026__F2 Evolution of a Cellular Immune Response in Drosophila: A Phenotypic and Genomic Comparative Analysis ENSG00000197471 ENSG00000166402 ENSG00000291837 ENSG00000291791 ENSG00000172936 ENSG00000146648 ENSG00000124827 PMC7590211__F4 TRIMs on proinflammatory STAT3 (A) and NFKB (B) signaling cascades in CRC ENSG00000104856 ENSG00000106785 ENSG00000137077 ENSG00000137699 ENSG00000069329 ENSG00000162924 ENSG00000168610 ENSG00000101557 PMC7590211__F2 Role of TRIMs in the control of p53 tumor-suppressor protein ENSG00000281324 ENSG00000134982 ENSG00000113595 ENSG00000170558 ENSG00000137699 ENSG00000026508 ENSG00000168036 ENSG00000119283 ENSG00000122779 ENSG00000121060 ENSG00000130726 PMC7402324__F1 Simplified scheme of canonical WNT -signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000111837 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC4485451__F1 BCR Signaling Pathway and Small Molecule Inhibitors of BCR Signaling ENSG00000177455 ENSG00000095585 ENSG00000198793 ENSG00000197943 ENSG00000010671 PMC6873206__F4 YAP regulation by focal adhesion signaling ENSG00000186575 ENSG00000291971 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC8641543__F1 Oncogenic factors regulate cancer cell metabolism ENSG00000198793 ENSG00000136997 PMC9570183__F1 Polyphenols as Potent Epigenetics Agents for Cancer ENSG00000134982 ENSG00000088305 ENSG00000164488 PMC8641543__F2 Inhibitors of glucose metabolism ENSG00000092621 ENSG00000159399 ENSG00000167701 PMC3185539__F1 Summary of NSP1 inhibition of the innate immune response pathway ENSG00000183735 ENSG00000115415 ENSG00000164342 PMC7492639__F1 Ozone-mediated effects on intracellular pathways involved in cell injury and inflammation ENSG00000162711 ENSG00000108691 ENSG00000107562 ENSG00000164430 ENSG00000137033 ENSG00000166090 ENSG00000079999 PMC7402324__F6 Compounds and antibodies affecting WNT/Beta-catenin-signaling pathway that were investigated in melanoma (preclinical studies, except for LGK974, which is tested in the clinical trial NCT01351103) ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000148798 ENSG00000168036 ENSG00000173273 PMC8831284__F3 Transcriptome-wide association study identifies novel blood-based gene biomarker candidates for Alzheimer’s disease risk ENSG00000284816 ENSG00000196388 ENSG00000130202 ENSG00000285395 ENSG00000172803 ENSG00000167840 ENSG00000164938 ENSG00000090238 ENSG00000106459 PMC5427281__F8 Model depicting the mechanism of phagocyte priming by apoptotic cells PMC5059336__F3 miRNAs modulation in direct cardiac reprogramming ENSG00000285109 ENSG00000164107 ENSG00000089225 PMC2965861__F1 The AMPK pathway in relation to various molecules ENSG00000198793 ENSG00000169710 PMC3129516__F2 SIRT3 and Cancer: Tumor Promoter or Suppressor? ENSG00000105835 ENSG00000142082 PMC7576205__F6 Inhibiting insulin and mTOR signaling by afatinib and crizotinib combination fosters broad cytotoxic effects in cutaneous malignant melanoma ENSG00000167601 ENSG00000033327 ENSG00000169047 ENSG00000198793 ENSG00000108443 ENSG00000141564 ENSG00000140443 PMC8268497__F2 Small Molecules and Their Effect on the Molecular Mechanisms of Early Retinal Organoid Development ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC8268497__F3 Small Molecules and Their Effect on the Molecular Mechanisms of Early Retinal Organoid Development ENSG00000198793 PMC2703803__F1 The Heme Biosynthetic Pathway of the Obligate Wolbachia Endosymbiont of Brugia malayi as a Potential Anti-filarial Drug Target ENSG00000144410 ENSG00000126088 ENSG00000188690 PMC4435535__F1 Notch signaling as a novel regulator of metabolism ENSG00000169710 ENSG00000124253 ENSG00000168610 PMC4435535__F2 Notch signaling as a novel regulator of metabolism ENSG00000109819 ENSG00000042832 ENSG00000142611 ENSG00000125538 PMC10474053__F3 PI3K-AKT pathway and major upstream effectors in the signaling network ENSG00000109452 ENSG00000002330 ENSG00000164327 PMC9556862__F1 Using Clustered Regularly Interspaced Short Palindromic Repeats gene editing to induce permanent expression of fetal hemoglobin in Beta-thalassemia and sickle cell disease: A comparative meta-analysis ENSG00000105610 ENSG00000111642 PMC4905314__F1 ER stress induced by oncogenic BRAF and modulation of basal autophagy in melanoma ENSG00000128272 ENSG00000144895 ENSG00000198793 ENSG00000127191 PMC6396338__F6 Contrasting strategies for disrupting interferon (IFN)-mediated responses in hepatitis A virus (HAV) versus hepatitis E virus (HEV) infections ENSG00000088888 ENSG00000105397 ENSG00000164342 PMC8891817__F18 Mulberrin confers protection against hepatic fibrosis by Trim31/Nrf2 signaling ENSG00000169245 ENSG00000162711 ENSG00000181019 ENSG00000125538 ENSG00000108821 ENSG00000023909 PMC10474053__F6 Ca2+-mediated inhibition of membrane localization of PIP-binding proteins ENSG00000156026 PMC10474053__F5 Dysregulation of Ca2+ channels and pumps in metabolic diseases ENSG00000167323 ENSG00000156026 ENSG00000112561 ENSG00000160741 PMC5834520__F1 Osteopontin in the progression of solid organ tumour ENSG00000152592 ENSG00000152591 PMC7699570__F2 Signaling targets of CO ENSG00000162711 ENSG00000189403 PMC5834520__F2 Osteopontin in the progression of solid organ tumour ENSG00000138798 ENSG00000026508 ENSG00000146648 PMC11660139__F8 Inhibition of miR-675 on TGFB signaling and OC progression PMC9355713__F3 Therapeutic application of quercetin in aging-related diseases: SIRT1 as a potential mechanism ENSG00000162711 ENSG00000128272 ENSG00000079999 PMC3100753__F4 Regulation of the estrogen signaling pathway inside the nucleus ENSG00000175029 ENSG00000141456 PMC5441870__F3 Central metabolism of T ENSG00000124479 ENSG00000137996 ENSG00000105402 PMC4904747__F16 JAK STAT pathway ENSG00000115415 PMC3272176__F1 Signal Transduction pathways downstream of activated HER family of receptors ENSG00000198793 PMC5805715__F4 The gene targets of miRNA identified by NGS in the AIS patients and their role in osteoblast and osteoclast differentiation depicted from KEGG and DIANA miRPath v3 ENSG00000170365 ENSG00000134982 ENSG00000291837 ENSG00000168036 ENSG00000162599 ENSG00000143387 PMC11018134__F7 FBL Promotes LPS-Induced Neuroinflammation by Activating the NFKB Signaling Pathway ENSG00000170458 ENSG00000172936 ENSG00000280548 PMC9311231__F3 Metabolic assessment of tumors reveals alternative pathways for Trp catabolism ENSG00000197444 PMC5984668__F1 STATus of STAT3 in Psoriatic Arthritis ENSG00000184451 ENSG00000168610 ENSG00000112486 ENSG00000106546 PMC6429030__F2 TLR2/IFN-λ3 protein-protein interaction was performed by using String software ENSG00000291876 ENSG00000113520 ENSG00000168610 PMC8472352__F2 New Functions of Vav Family Proteins in Cardiovascular Biology, Skeletal Muscle, and the Nervous System ENSG00000291971 ENSG00000149269 ENSG00000160293 PMC5756134__F2 An Unexpected Friend – ROS in Apoptosis-induced Compensatory Proliferation: implications for regeneration and cancer ENSG00000110711 PMC7962738__F2 Glutamine synthesis, nucleotide biosynthesis, and the pentose-phosphate pathway ENSG00000197713 ENSG00000167900 ENSG00000254550 ENSG00000128050 ENSG00000162368 ENSG00000004455 ENSG00000291814 ENSG00000167325 ENSG00000171848 ENSG00000171793 ENSG00000047230 ENSG00000143179 ENSG00000084774 PMC8811913__F6 Transition Toward Nitrogen Deprivation in Diatoms Requires Chloroplast Stand-By and Deep Metabolic Reshuffling ENSG00000134986 PMC7962738__F1 Glycolysis, gluconeogenesis, glycogen metabolism, the hexosamine pathway, oxidative phosphorylation, and the TCA cycle ENSG00000143158 ENSG00000147162 ENSG00000173599 ENSG00000105953 ENSG00000124253 ENSG00000060762 ENSG00000062485 PMC7544648__F1 Mechanisms of alcohol-induced microglial eCIRP in promoting AD pathology ENSG00000162711 ENSG00000189403 ENSG00000136869 ENSG00000168610 PMC5403593__F3 Cartoon illustrating two independent parallel pathways in the post-mitosis G1 phase (G1-pm) in cell proliferation: MAPK and the Hippo pathways ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC3422784__F5 Sensing the environment: Regulation of local and global homeostasis by the skin neuroendocrine system ENSG00000065833 ENSG00000165841 ENSG00000139287 ENSG00000129167 PMC3541667__F5 Hypothetic model explaining how KDM6 may contribute to definitive endoderm differentiation ENSG00000168036 ENSG00000132510 ENSG00000277641 PMC6958404__F1 Major Signalling Pathways Involved in Hepcidin Regulation ENSG00000170365 ENSG00000137834 ENSG00000010704 ENSG00000095739 ENSG00000106327 ENSG00000187045 ENSG00000178752 ENSG00000128791 ENSG00000168610 ENSG00000127948 ENSG00000130513 PMC5403593__F2 Cell cycle phases and two examples of independent core pathways in the G1 stage ENSG00000159224 ENSG00000168036 PMC4846832__F6 Discovery of new MD2 inhibitor from chalcone derivatives with anti-inflammatory effects in LPS-induced acute lung injury ENSG00000172936 ENSG00000136869 ENSG00000184216 PMC7543703__F2 NSAIDs inhibit the synthesis of prostaglandins that protect against COVID-19 PMC8602059__F1 Crosstalk Between Regulatory Non-Coding RNAs and Nuclear Factor Kappa B in Hepatocellular Carcinoma ENSG00000104856 ENSG00000168884 ENSG00000264522 ENSG00000102871 ENSG00000165280 ENSG00000111321 ENSG00000127191 ENSG00000082512 ENSG00000157625 ENSG00000172936 ENSG00000131323 ENSG00000083799 ENSG00000175104 PMC6850914__F1 Signal transduction pathways initiated by IL‐29 ENSG00000213928 ENSG00000105397 ENSG00000131196 PMC6525179__F5 Gene expression and 14C fatty acids production in LC-PUFA synthesis pathway of liver between knockout (KO) and wildtype (WT) salmon ENSG00000118402 ENSG00000197977 ENSG00000135678 PMC6854382__F10 Study on the mechanism of the MPAPO promoting of corneal wound repair and axonal regeneration (A) MPAPO activates the classic Wnt/Beta-catenin signaling pathway through the PAC1 receptor ENSG00000135446 ENSG00000168036 ENSG00000105810 ENSG00000171791 PMC8113731__F1 Mitotic kinases as drivers of the epithelial-to-mesenchymal transition and as therapeutic targets against breast cancers ENSG00000117650 PMC4508581__F4 Model illustrating the relationship between hypoxia, ER stress, and activation of the unfolded protein response ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC2788213__F4 Systems-Level Comparison of Host-Responses Elicited by Avian H5N1 and Seasonal H1N1 Influenza Viruses in Primary Human Macrophages ENSG00000088888 ENSG00000197471 ENSG00000164342 PMC3536147__F3 Identification of Burkholderia cenocepacia Strain H111 Virulence Factors Using Nonmammalian Infection Hosts ENSG00000185129 ENSG00000146676 PMC9638168__F2 MicroRNAs in Kawasaki disease: An update on diagnosis, therapy and monitoring ENSG00000100234 ENSG00000137834 ENSG00000111837 ENSG00000100985 ENSG00000281879 ENSG00000168610 ENSG00000136826 PMC6185734__F9 Magnetic fields affects microtubules via EGFR and calcium pathways ENSG00000138798 ENSG00000146648 PMC7849182__F8 Schematic showing multiple signaling pathways of HSYA ENSG00000180210 ENSG00000198793 ENSG00000172936 ENSG00000136869 PMC8447736__F4 Bioinformatics analysis of SARS-CoV-2 infection-associated immune injury and therapeutic prediction for COVID-19 ENSG00000149968 ENSG00000196549 ENSG00000111837 ENSG00000105656 ENSG00000007908 ENSG00000168040 ENSG00000164305 PMC12151402__F1 Proposed effect of CHEK2 loss of function on cytotoxic T-cell recruitment at different organizational levels ENSG00000149311 ENSG00000175054 ENSG00000164430 ENSG00000183765 PMC8147131__F7 Metformin Dysregulates the Unfolded Protein Response and the WNT/Beta-Catenin Pathway in Endometrial Cancer Cells through an AMPK-Independent Mechanism ENSG00000128272 ENSG00000168036 PMC11502721__F2 Intestinal homeostasis by microenvironment ENSG00000169218 ENSG00000105329 ENSG00000138798 ENSG00000168036 ENSG00000198598 ENSG00000168610 ENSG00000062282 ENSG00000106546 ENSG00000146374 PMC8447736__F5 Bioinformatics analysis of SARS-CoV-2 infection-associated immune injury and therapeutic prediction for COVID-19 ENSG00000090402 ENSG00000146469 ENSG00000108788 ENSG00000127948 ENSG00000183395 PMC11502721__F3 Intestinal stem cells (ISCs) by glucose, fatty acid, and ketone body metabolism ENSG00000169710 ENSG00000159399 ENSG00000060762 PMC5627579__F3 Proximal tubule (PT) phosphate reabsorption ENSG00000118972 ENSG00000152266 ENSG00000143324 PMC4683444__F4 Using activation status of signaling pathways as mechanism-based biomarkers to predict drug sensitivity ENSG00000149311 ENSG00000117020 ENSG00000110330 ENSG00000002330 ENSG00000164399 ENSG00000164400 ENSG00000171791 ENSG00000160049 PMC9562620__F9 Xuanfei Baidu Formula attenuates LPS-induced acute lung injury by inhibiting the NFKB signaling pathway ENSG00000125538 PMC5448108__F7 A proposed model for the regulation and function of two Grp78 genes in JH-stimulated locust vitellogenesis ENSG00000144895 ENSG00000291971 ENSG00000166508 PMC3837055__F1 Schematic view of kallistatin action in the canonical Wnt pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5239457__F7 EIF2A serine 51 phosphorylation-ATF4 arm promotes HIPPO signaling and cell death under oxidative stress ENSG00000128272 ENSG00000144895 ENSG00000150907 ENSG00000150457 ENSG00000131023 ENSG00000123124 PMC10215824__F3 Obesity-altered adiponiche and tumour development: some novel proposed mechanisms in mature adipocytes and precursor cells ENSG00000198793 ENSG00000174059 ENSG00000150630 PMC9647059__F1 Neuroinflammation in retinitis pigmentosa: Therapies targeting the innate immune system ENSG00000162711 ENSG00000108691 ENSG00000136160 ENSG00000172936 ENSG00000128342 ENSG00000168610 ENSG00000115594 ENSG00000127129 PMC3192015__F1 Mammalian target of rapamycin, Akt, and phosphatidylinositol 3-kinase signaling ENSG00000164327 ENSG00000167965 PMC2684375__F1 Factors involved in the regulation of corporal smooth muscle tone ENSG00000163914 ENSG00000173786 ENSG00000145321 PMC4980583__F5 Thumbnail image of MAPK signalling pathway ENSG00000087095 ENSG00000175104 PMC5100880__F6 Sarcosine Up-Regulates Expression of Genes Involved in Cell Cycle Progression of Metastatic Models of Prostate Cancer ENSG00000002330 ENSG00000123374 ENSG00000171791 PMC5345976__F10 Scheme summarizing the protective effects of Xn on LPS-induced acute lung injury via activation of the AMPK/GSK3Beta-Nrf2 axis ENSG00000162711 ENSG00000125538 ENSG00000265972 PMC5100880__F7 Sarcosine Up-Regulates Expression of Genes Involved in Cell Cycle Progression of Metastatic Models of Prostate Cancer ENSG00000002330 ENSG00000123374 ENSG00000171791 PMC9301183__F1 NLRP3 inflammasome activation and SARS-CoV-2-mediated hyperinflammation, cytokine storm and neurological syndromes ENSG00000278718 ENSG00000162711 ENSG00000130234 ENSG00000125538 PMC6030217__F1 Role of NUAK1 in anti-oxidant signalling ENSG00000074590 ENSG00000136997 ENSG00000079999 PMC8018950__F3 Top regulatory effect predicted by Ingenuity Pathway Analysis within Fayoumis at 6 dpi comparison ENSG00000137033 ENSG00000165030 ENSG00000050748 ENSG00000140968 ENSG00000160179 ENSG00000049768 PMC5095680__F4 Impact of miR-140 overexpression on proteins involved in the NFKB signaling pathway ENSG00000186660 ENSG00000154736 ENSG00000125538 ENSG00000158859 PMC5382464__F1 Significantly up-regulated genes during analysed training periods in Arabian horse blood that belong to the FoxO signalling pathway (KEGG ecb04068) ENSG00000145604 ENSG00000149311 ENSG00000087095 ENSG00000171105 ENSG00000138798 ENSG00000213445 ENSG00000123374 ENSG00000145782 ENSG00000168610 ENSG00000146648 ENSG00000168685 PMC5784915__F6 Inferring hidden causal relations between cancer and normal networks ENSG00000166167 ENSG00000280962 ENSG00000002330 ENSG00000170027 ENSG00000198793 ENSG00000110931 ENSG00000164327 ENSG00000281877 ENSG00000141564 ENSG00000171791 ENSG00000069956 ENSG00000135341 ENSG00000132356 ENSG00000072803 ENSG00000164305 ENSG00000111725 ENSG00000115317 ENSG00000181929 ENSG00000175634 ENSG00000177189 ENSG00000100387 ENSG00000162409 ENSG00000162607 ENSG00000253729 PMC9617413__F4 Transcriptomic and metabolomic analyses for providing insights into the influence of polylysine synthetase on the metabolism of Streptomyces albulus ENSG00000112977 ENSG00000117118 PMC9233553__F2 Coronaviral PLpro proteases and the immunomodulatory roles of conjugated versus free Interferon Stimulated Gene product-15 (ISG15) ENSG00000184979 ENSG00000111537 ENSG00000187608 ENSG00000105397 PMC5784915__F7 Inferring hidden causal relations between pathway members using reduced Google matrix of directed biological networks ENSG00000114346 ENSG00000178999 ENSG00000087586 ENSG00000135476 ENSG00000073111 ENSG00000101224 ENSG00000145386 ENSG00000144354 ENSG00000111665 ENSG00000100749 ENSG00000134057 ENSG00000143476 ENSG00000132646 ENSG00000171848 ENSG00000197299 ENSG00000076382 ENSG00000138180 ENSG00000136108 ENSG00000134690 PMC10845297__F3 Fibroblasts of metastatic organ in PMN formation ENSG00000108702 ENSG00000179934 ENSG00000118503 ENSG00000078098 PMC4745841__F7 Functional interpretation of the IL-6 gene signature and its relationship to the three main downstream pathways of IL-6.Notes: The 17 genes are part of the Jak-STAT IL-6 downstream pathway ENSG00000148346 ENSG00000143546 ENSG00000151632 ENSG00000163220 ENSG00000185885 ENSG00000221869 ENSG00000143556 ENSG00000168610 ENSG00000187134 ENSG00000196136 ENSG00000185201 ENSG00000142089 ENSG00000103534 PMC6099083__F5 Tumor Epigenetically Upregulated Genes (EUG) in Epstein-Barr Virus Infection pathway ENSG00000111537 ENSG00000069869 ENSG00000026508 ENSG00000105639 ENSG00000175104 ENSG00000168610 PMC10085880__F7 In silico identification of potential miRNAs -mRNA inflammatory networks implicated in the pathogenesis of COVID-19 ENSG00000162711 ENSG00000213928 ENSG00000160710 ENSG00000131323 ENSG00000164342 PMC9265283__F5A Tissue-Based Proteomic Profiling in Patients with Hyperplasia and Endometrial Cancer ENSG00000115484 ENSG00000186395 ENSG00000291420 PMC3826456__F2 Diagram of PI3K/Akt and Ras/Raf pathway (see text for details) ENSG00000169047 ENSG00000146648 PMC2670830__F4 Signaling in pterygium ENSG00000121552 ENSG00000159388 ENSG00000113140 ENSG00000177606 PMC2932530__F9 Redox regulation of the PI3K/Akt signaling pathway ENSG00000124102 ENSG00000002330 PMC2733082__F2 InterferonG signaling pathway and mutations in its components found in human uterine leiomyosarcoma ENSG00000115415 ENSG00000125347 PMC8739172__F4 Exploring the Mechanism of Panax notoginseng Saponins against Alzheimer's Disease by Network Pharmacology and Experimental Validation ENSG00000168003 ENSG00000198793 ENSG00000163914 ENSG00000164327 PMC6836530__F8 Schematic diagram of the molecular mechanisms underlying NOTCH2-regulated EMT ENSG00000175104 PMC8465509__F2 Emergence of Cardiac Glycosides as Potential Drugs: Current and Future Scope for Cancer Therapeutics ENSG00000291971 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC9399684__F2 Modulation of ion channels in cancer chemo-resistance ENSG00000187688 ENSG00000002330 ENSG00000133937 ENSG00000026508 ENSG00000168036 ENSG00000136826 PMC2525561__F4 Schematic diagram of in vivo n3 VLC-PUFA biosynthetic pathway mediated by ELOVL4 and other ELO families [modified after Suh and Clandinin ()] ENSG00000118402 ENSG00000119915 ENSG00000066322 ENSG00000197977 PMC5485329__F3 AMPK and mTOR pathway by Sestrins ENSG00000177169 ENSG00000198793 ENSG00000086991 PMC5382464__F2 Significantly up-regulated genes during analysed training periods in Arabian horse blood that belong to the PI3K-Akt signalling pathway (KEGG ecb04151) ENSG00000177455 ENSG00000124102 ENSG00000103479 ENSG00000002330 ENSG00000105401 ENSG00000186716 ENSG00000198793 PMC6593125__F1 T-cell receptor (TCR) signaling ENSG00000213658 PMC4741479__F4 Radiosensitivity MiRNA signature validated by the TCGA database for head and neck squamous cell carcinomas ENSG00000149311 ENSG00000088305 ENSG00000102245 ENSG00000135446 ENSG00000128052 ENSG00000185591 ENSG00000105810 ENSG00000171791 ENSG00000112715 ENSG00000124762 PMC7310461__F4 Alterations in TCR signaling pathway ENSG00000140992 ENSG00000065675 ENSG00000291603 ENSG00000282905 ENSG00000070831 ENSG00000134215 ENSG00000163599 ENSG00000105647 ENSG00000135341 ENSG00000100485 ENSG00000121879 ENSG00000141968 ENSG00000213658 ENSG00000149269 ENSG00000113520 ENSG00000164400 ENSG00000160293 ENSG00000124181 ENSG00000113525 ENSG00000198286 ENSG00000104365 ENSG00000188386 ENSG00000100906 ENSG00000081237 ENSG00000109320 ENSG00000269335 ENSG00000173039 ENSG00000213341 ENSG00000043462 ENSG00000188389 ENSG00000120910 ENSG00000221823 ENSG00000111537 ENSG00000135446 ENSG00000102245 ENSG00000010810 ENSG00000177606 ENSG00000171608 ENSG00000131196 ENSG00000135605 ENSG00000130669 PMC7310461__F5 Alterations in the BCR signaling pathway ENSG00000070190 ENSG00000282905 ENSG00000134215 ENSG00000104972 ENSG00000115904 ENSG00000110651 ENSG00000149308 ENSG00000105647 ENSG00000186818 ENSG00000100485 ENSG00000276798 ENSG00000121879 ENSG00000274513 ENSG00000010671 ENSG00000095585 ENSG00000177455 ENSG00000169750 ENSG00000165458 ENSG00000166501 ENSG00000197943 ENSG00000160293 ENSG00000198286 ENSG00000274935 ENSG00000104365 ENSG00000188386 ENSG00000105369 ENSG00000276175 ENSG00000275584 ENSG00000100906 ENSG00000109320 ENSG00000007312 ENSG00000269335 ENSG00000173039 ENSG00000185885 ENSG00000152689 ENSG00000213341 ENSG00000273991 ENSG00000117322 ENSG00000120910 ENSG00000221823 ENSG00000072694 ENSG00000239998 ENSG00000177606 ENSG00000171608 ENSG00000131196 PMC11958781__F9 Mechanistic diagram illustrates that KLF6 cooperates with FOSL2 to promote H3K23su levels and enhance 5-FU resistance in HCT15-FR cells ENSG00000075223 ENSG00000168036 PMC4077717__F1 Overview of the general innate immune response to viral infection ENSG00000213928 ENSG00000187608 ENSG00000089127 ENSG00000157601 ENSG00000163565 ENSG00000185745 ENSG00000185885 ENSG00000276561 ENSG00000142166 ENSG00000183735 ENSG00000134321 ENSG00000164430 ENSG00000088888 ENSG00000138135 ENSG00000105397 ENSG00000115415 ENSG00000243646 ENSG00000172936 ENSG00000140464 ENSG00000164342 PMC8555304__F3 Chemoprotective and chemosensitizing effects of apigenin on cancer therapy ENSG00000002330 ENSG00000079999 PMC1885990__F1 Scheme depicting a molecular pathway by which cell-cycle-related molecules promote cell death in neurons in development and disease ENSG00000101945 ENSG00000135446 ENSG00000205250 PMC3096978__F4 Functional network connections between HRneg/Tneg signature genes ENSG00000111537 ENSG00000185386 ENSG00000145681 ENSG00000182473 ENSG00000117152 ENSG00000126353 ENSG00000185591 ENSG00000168610 ENSG00000143632 PMC7310461__F3 Alterations in SLE signaling pathway based on calculated final parameters ENSG00000150337 ENSG00000244731 ENSG00000143226 ENSG00000182326 ENSG00000236625 ENSG00000277571 ENSG00000277263 ENSG00000167088 ENSG00000231021 ENSG00000039537 ENSG00000113600 ENSG00000246705 ENSG00000099284 ENSG00000100448 ENSG00000197903 ENSG00000275713 ENSG00000124635 ENSG00000123569 ENSG00000275126 ENSG00000164032 ENSG00000276368 ENSG00000274290 ENSG00000176919 ENSG00000188375 ENSG00000233822 ENSG00000157131 ENSG00000273703 ENSG00000203747 ENSG00000276410 ENSG00000275663 ENSG00000111537 ENSG00000286522 ENSG00000179344 ENSG00000102245 ENSG00000184270 ENSG00000203852 ENSG00000288512 PMC6687721__F7 The synergistic effects of oxaliplatin and piperlongumine on colorectal cancer are mediated by oxidative stress ENSG00000132906 ENSG00000128272 ENSG00000144895 ENSG00000164305 PMC2151384__F2 CON and NR samples; black/white boxes denote genes not detected on the human genechip with baboon RNA generated probe ENSG00000198793 ENSG00000164327 ENSG00000168610 PMC9090500__F7 Rapid Inflammasome Activation Is Attenuated in Post-Myocardial Infarction Monocytes ENSG00000162711 ENSG00000150782 ENSG00000118503 PMC9362342__F1 Cellular senescence and the SASP ENSG00000149311 ENSG00000175054 ENSG00000168283 ENSG00000157557 ENSG00000285109 ENSG00000163739 ENSG00000135446 ENSG00000198793 PMC3326643__F2 Targeting Mnks for Cancer Therapy ENSG00000163435 ENSG00000169047 ENSG00000196712 PMC8932957__F2 Conserved nutrient-sensing response pathways in worms, flies and mammals ENSG00000136997 ENSG00000112561 PMC8052137__F6 Underlying Molecular Mechanisms Involved in Traditional Chinese Medicine Smilax china L. for the Treatment of Pelvic Inflammatory Disease ENSG00000148346 ENSG00000087245 ENSG00000197901 ENSG00000011422 ENSG00000082175 ENSG00000100985 ENSG00000005381 ENSG00000073756 ENSG00000168610 ENSG00000023839 ENSG00000163631 PMC12029909__F5 Screening for maps of metabolic pathways involved in key differentially expressed metabolites ENSG00000142192 ENSG00000122966 ENSG00000172005 PMC6718556__F5 Several metabolic mechanisms may provide an advantage to Tregs in the tumor microenvironment ENSG00000135218 ENSG00000026103 PMC6533481__F7 The molecular mechanism involved lncRNA MEG3 affecting the fraction healing of mice after tibia fracture ENSG00000169884 ENSG00000168036 PMC8554124__F9 Systematic Review of Transcriptional Dysregulation in Huntington’s Disease Studied by RNA Sequencing PMC9656133__F6A Integrated Multi-Omic Characterization of the Detachment Process of Adherent Vero Cells with Animal-Based and Animal-Origin-Free Enzymes ENSG00000002549 PMC2743781__F3 NAD biosynthetic pathways from nicotinamde and nicotinic acid in yeast, invertebrates, and mammals ENSG00000105835 ENSG00000157064 ENSG00000173614 PMC6549095__F7 Qigesan reduces the motility of esophageal cancer cells via inhibiting Gas6/Axl and NFKB expression ENSG00000167601 ENSG00000087245 ENSG00000100985 PMC8451004__F4 Integrated analyses of long noncoding RNAs and mRNAs in the progression of breast cancer ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 PMC10741662__F1 WNT/Beta-catenin signaling pathway ENSG00000154856 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3546740__F2 Simplified schematic overview of the biosynthesis of the main secondary metabolites stored and/or secreted by tomato glandular trichome cells ENSG00000197429 ENSG00000026103 PMC2889494__F3 Protein components of the pheromone response network constructed by the PCST approach ENSG00000175854 ENSG00000186635 ENSG00000130234 ENSG00000091651 PMC8894239__F3 mTOR-Mediated Regulation of Immune Responses in Cancer and Tumor Microenvironment ENSG00000174125 ENSG00000101751 ENSG00000105329 ENSG00000049768 PMC9311918__F1 mTOR Signalling Pathway: A Potential Therapeutic Target for Ocular Neurodegenerative Diseases ENSG00000128272 ENSG00000126775 ENSG00000158828 ENSG00000112561 PMC8894239__F1 mTOR-Mediated Regulation of Immune Responses in Cancer and Tumor Microenvironment ENSG00000155792 PMC9311918__F3 mTOR Signalling Pathway: A Potential Therapeutic Target for Ocular Neurodegenerative Diseases ENSG00000169047 ENSG00000198793 ENSG00000155792 ENSG00000167965 PMC11668900__F1 Mechanisms affecting gastric epithelial cell plasticity ENSG00000281324 ENSG00000117425 ENSG00000162337 ENSG00000070831 ENSG00000134982 ENSG00000170558 ENSG00000168036 ENSG00000090932 ENSG00000121966 ENSG00000106571 ENSG00000128917 ENSG00000166813 ENSG00000136997 ENSG00000019549 ENSG00000272398 ENSG00000128602 PMC6829565__F6 Schematic diagram depicting the MAPK/ELK1 signaling pathway linking Ang II-RBM20-titin splicing ENSG00000203867 ENSG00000155657 PMC8583510__F5 Mitochondria as a Cellular Hub in Infection and Inflammation ENSG00000174125 ENSG00000278718 ENSG00000162711 ENSG00000130159 ENSG00000276561 ENSG00000150782 ENSG00000239732 ENSG00000088888 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC3127159__F2 TPO signaling pathway ENSG00000171791 PMC12050339__F7 Molecular pathways involved in the mechanism of mLV injury ENSG00000168329 ENSG00000176692 ENSG00000117707 ENSG00000146648 ENSG00000103335 ENSG00000150630 PMC6298397__F3 Central metabolic pathway of representative carbon sources in model iZBM1060 (detailed information on enzyme information and reactions are presented in Supplementary Table ) ENSG00000159224 ENSG00000122966 ENSG00000128052 ENSG00000172005 ENSG00000082212 PMC5932555__F2 Design and application of scaffold RNAs controlling both genomic target sequence and regulatory function PMC9687450__F5 UPLC-QTOF/MS Metabolomics and Biochemical Assays Reveal Changes in Hepatic Nutrition and Energy Metabolism during Sexual Maturation in Female Rainbow Trout (Oncorhynchus mykiss) ENSG00000100290 ENSG00000042832 ENSG00000173599 PMC8582418__F3 Neglected Liaison: Targeting Cancer Cell Metabolic Reprogramming Modifies the Composition of Non-Malignant Populations of the Tumor Microenvironment ENSG00000169710 ENSG00000115419 PMC4110160__F1 Differential LSEC Signalling in Models of Acute or Chronic Injury ENSG00000019991 ENSG00000077782 ENSG00000121966 PMC3880197__F2 Reactive oxygen species in cancer ENSG00000291971 PMC11056316__F9 Schematic illustration outlining the mechanism by which PIN operates during osteoclastogenesis ENSG00000147614 ENSG00000102575 ENSG00000100985 ENSG00000175104 ENSG00000131196 PMC8623999__F7 Exercise Training Alleviates Cardiac Fibrosis through Increasing Fibroblast Growth Factor 21 and Regulating TGFB1-Smad2/3-MMP2/9 Signaling in Mice with Myocardial Infarction ENSG00000087245 ENSG00000105550 ENSG00000100985 PMC7843416__F1 Type I interferonopathy-associated genes are involved in the sensing and metabolism of viral RNA ENSG00000026297 PMC2810486__F1 The Potential of p38 MAPK Inhibitors to Modulate Periodontal Infections ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 PMC8395241__F7 Analysis of PPARG Signaling Activity in Psoriasis ENSG00000140992 ENSG00000243414 ENSG00000291971 ENSG00000095015 ENSG00000169032 ENSG00000135341 ENSG00000127666 ENSG00000168610 ENSG00000132170 ENSG00000112116 ENSG00000177606 ENSG00000172936 ENSG00000175104 ENSG00000112115 ENSG00000146648 PMC5497685__F1 Ca2+ regulates different steps of autophagy ENSG00000124102 ENSG00000177169 ENSG00000198793 ENSG00000112561 PMC4096794__F8 Sumoylation Pathway Is Required to Maintain the Basal Breast Cancer Subtype ENSG00000087510 ENSG00000137203 ENSG00000129514 PMC7689098__F1 KLF9 regulates cAMP signaling pathway genes in HT22 cells ENSG00000104899 ENSG00000156299 ENSG00000163914 ENSG00000177606 ENSG00000160293 PMC7689098__F2 KLF13 regulates cAMP signaling pathway genes in HT22 cells ENSG00000104899 ENSG00000156299 ENSG00000149269 ENSG00000163914 ENSG00000177606 ENSG00000160293 PMC3720582__F1 Comprehensive Hedgehog Signaling Pathway ENSG00000157933 ENSG00000117425 ENSG00000148400 ENSG00000020633 ENSG00000118971 ENSG00000196628 ENSG00000106571 ENSG00000164161 ENSG00000078747 ENSG00000144857 ENSG00000139549 ENSG00000133961 ENSG00000164690 ENSG00000128602 ENSG00000163501 ENSG00000026103 PMC3720582__F2 Structural and Logical Analysis of a Comprehensive Hedgehog Signaling Pathway to Identify Alternative Drug Targets for Glioma, Colon and Pancreatic Cancer ENSG00000157933 ENSG00000117425 ENSG00000020633 ENSG00000171791 ENSG00000196628 ENSG00000124216 ENSG00000180447 ENSG00000164161 ENSG00000078747 ENSG00000144857 ENSG00000139549 ENSG00000133961 ENSG00000164690 ENSG00000128602 ENSG00000163501 PMC6038002__F10 Tim‐3 exacerbates kidney ischaemia/reperfusion injury through the TLR‐4/NF‐KB signalling pathway and an NLR‐C4 inflammasome activation ENSG00000136869 ENSG00000091106 PMC7689098__F9 Proposed model for the repressive actions of KLF9 and KLF13 on cAMP-dependent neurite-outgrowth ENSG00000119138 PMC4121837__F6 Proposed model for 18-5p–mediated inhibition of viral reactivation through the MAPK signal transduction pathway ENSG00000169967 ENSG00000186716 PMC8123704__F5 Dipterocarpus tuberculatus Roxb. Ethanol Extract Has Anti-Inflammatory and Hepatoprotective Effects In Vitro and In Vivo by Targeting the IRAK1/AP-1 Pathway ENSG00000125538 ENSG00000172936 ENSG00000184216 PMC3032466__F11 Expression of cell cycle genes in wild-type (WT) and CKX-4 tubers after GA3-mediated tuber sprouting ENSG00000134982 ENSG00000117399 PMC8305988__F4 Personalized Genomics Approach of the Prostate Cancer ENSG00000132906 ENSG00000117020 ENSG00000002330 ENSG00000005339 ENSG00000100906 ENSG00000198793 ENSG00000168036 ENSG00000213341 ENSG00000100985 ENSG00000146648 ENSG00000124762 PMC3679038__F7 Involvement of ERK-Nrf-2 Signaling in Ionizing Radiation Induced Cell Death in Normal and Tumor Cells ENSG00000198517 ENSG00000079999 PMC9133881__F5 miR-29a-5p Inhibits Prenatal Hair Placode Formation Through Targeting EDAR by ceRNA Regulatory Network ENSG00000186197 ENSG00000122966 ENSG00000135960 ENSG00000078579 ENSG00000173599 ENSG00000104371 ENSG00000168036 PMC6566851__F5 Effect of butyrate on the Wnt signaling pathway Butyrate can increase Wnt1/2/3 expression, which bind to their receptor Fzd to activate Wnt signaling pathway ENSG00000168036 ENSG00000277641 ENSG00000125084 PMC9005359__F5 Risk-Related Genes and Associated Signaling Pathways of Gastrointestinal Stromal Tumors ENSG00000149311 ENSG00000175054 ENSG00000285109 ENSG00000011028 ENSG00000064393 ENSG00000276051 PMC12090635__F2 EMT and Notch signaling pathway ENSG00000148400 ENSG00000168785 ENSG00000285426 ENSG00000136518 ENSG00000137845 ENSG00000168610 PMC6566851__F8 Crosstalk of signaling pathways under butyrate influence ENSG00000168610 ENSG00000026103 PMC12090635__F1 Composition and activation of Notch signaling pathway ENSG00000128917 ENSG00000184916 ENSG00000090932 PMC4850467__F1 Different compounds in cigarette smoke regulate EMT ENSG00000291971 ENSG00000171759 ENSG00000106546 PMC8399643__F3 Regulatory roles of aminoacyl-tRNA synthetase in cardiovascular disease ENSG00000128272 ENSG00000185591 ENSG00000100219 ENSG00000167182 PMC2914561__F1 Translation control of gene expression ENSG00000144895 ENSG00000198793 ENSG00000092847 PMC6474359__F2 IL-17 family of cytokines in health and disease ENSG00000196843 ENSG00000002330 ENSG00000082512 ENSG00000175104 ENSG00000127191 ENSG00000163702 ENSG00000084774 PMC9658645__F3 Monocyte, a Maestro in the Tumor Microenvironment (TME) of Breast Cancer ENSG00000189377 ENSG00000275385 ENSG00000138798 ENSG00000113140 ENSG00000184371 ENSG00000112715 PMC6679138__F3 Proposed model for the cellular response to complex DNA damage (CDD) induced by proton beam therapy (PBT) in chromatin ENSG00000155827 ENSG00000174579 PMC9062296__F8 Endolymphatic Hydrop Phenotype in Familial Norrie Disease Caused by Large Fragment Deletion of NDP ENSG00000162337 ENSG00000106025 ENSG00000174804 PMC8569703__F1 Contextual Essentiality of Mitochondrial Genes in Cancer ENSG00000169021 ENSG00000130204 ENSG00000128951 ENSG00000131495 ENSG00000163528 ENSG00000100033 ENSG00000102967 ENSG00000291944 ENSG00000110536 ENSG00000143252 ENSG00000182511 ENSG00000173599 ENSG00000170855 ENSG00000138777 ENSG00000168924 ENSG00000243927 ENSG00000136003 ENSG00000162851 ENSG00000173085 ENSG00000062485 PMC8299562__F2 Neuropeptide Y and Metabolism Syndrome: An Update on Perspectives of Clinical Therapeutic Intervention Strategies ENSG00000198793 ENSG00000110931 ENSG00000168610 PMC6108178__F3 Primary myelofibrosis based on results obtained in animal models ENSG00000117400 PMC5476263__F2 Small molecule inhibitors uncover synthetic genetic interactions of human flap endonuclease 1 (FEN1) with DNA damage response genes ENSG00000149311 ENSG00000175054 ENSG00000144554 ENSG00000197299 ENSG00000276787 PMC4890621__F2 BIOPROSTHETIC HEART VALVES OF THE FUTURE ENSG00000026508 ENSG00000174059 ENSG00000132693 PMC11952772__F2 Lactobacillus regulate skeletal muscle pathways through short-chain fatty acids ENSG00000198793 PMC11952772__F1 Possible mechanism of Lactobacillus alleviating sarcopenia ENSG00000154059 ENSG00000136869 PMC4861839__F1 Inositide signaling pathway and target agents used to treat gastric cancer and colorectal cancer ENSG00000198793 ENSG00000164327 PMC6463672__F8 LINC01354 and Wnt/beta-catenin signaling pathway ENSG00000137673 ENSG00000168036 ENSG00000138668 ENSG00000196628 PMC7903614__F6 Primary paracrine and autocrine signalling contributes to cholesteatoma pathogenesis upon activation of the TLR4 pathway ENSG00000019991 ENSG00000124882 ENSG00000138798 ENSG00000125538 ENSG00000136869 PMC8353874__F2 Triple-negative breast cancer: understanding Wnt signaling in drug resistance ENSG00000141448 ENSG00000122691 ENSG00000138798 ENSG00000198793 ENSG00000288335 ENSG00000168036 ENSG00000168610 ENSG00000146648 PMC8353874__F1 Triple-negative breast cancer: understanding Wnt signaling in drug resistance ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000100592 ENSG00000134982 ENSG00000026508 ENSG00000168036 ENSG00000146648 PMC10037512__F6 Mechanism of STX5 involvement in HCC metastasis ENSG00000198793 ENSG00000084774 PMC6027047__F1 Metabolic activation of aristolochic acid I (AA-I), 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), 5-methylchrysene, and tamoxifen are shown as prototypes of procarcinogens ENSG00000181019 ENSG00000146247 ENSG00000119912 ENSG00000127948 PMC5562846__F1 Simplified scheme of chromatin changes in response to double-strand break (DSB) occurrence highlighting a central role of the ATM kinase ENSG00000149311 ENSG00000163961 ENSG00000112130 PMC8862475__F7 Combined inhibition of HMGCoA reductase and mitochondrial complex I induces tumor regression of BRAF inhibitor-resistant melanomas ENSG00000122966 ENSG00000198793 PMC7803748__F4 Muscle atrophy and hypertrophy: implications in health and disease ENSG00000102871 ENSG00000169047 ENSG00000175104 ENSG00000127191 PMC7803748__F1 Muscle atrophy and hypertrophy: implications in health and disease ENSG00000130939 ENSG00000177169 ENSG00000198793 ENSG00000169047 ENSG00000164327 ENSG00000108671 ENSG00000103264 ENSG00000139112 ENSG00000101557 ENSG00000068878 PMC7803748__F2 Muscle atrophy and hypertrophy: implications in health and disease ENSG00000170365 ENSG00000137834 ENSG00000198793 ENSG00000135414 PMC8024302__F4 Effect of extracellular vesicles on the regulation of mitochondria under hypoxia ENSG00000162711 ENSG00000239732 ENSG00000125538 ENSG00000172936 PMC8024302__F5 Effect of extracellular vesicles on the regulation of mitochondria under hypoxia ENSG00000177169 ENSG00000168958 ENSG00000116688 PMC2952980__F1 Multifactorial pathway leading to gastric carcinoma ENSG00000125538 ENSG00000112246 ENSG00000136869 PMC3548018__F2 Integrated scheme for MIF expression, signal transduction and regulation of glucocorticoid immunosuppression and cell survival ENSG00000162889 ENSG00000019582 ENSG00000291971 ENSG00000026508 ENSG00000121966 PMC8533092__F1 Non-Alcoholic Fatty Liver Disease in Lean and Non-Obese Individuals: Current and Future Challenges ENSG00000213996 ENSG00000137033 ENSG00000100344 ENSG00000125538 ENSG00000198911 PMC8851862__F3 Gene losses may contribute to subterranean adaptations in naked mole-rat and blind mole-rat ENSG00000114670 ENSG00000149311 ENSG00000175054 ENSG00000138346 ENSG00000135446 ENSG00000123374 ENSG00000051180 ENSG00000105810 ENSG00000138385 ENSG00000168101 PMC5643752__F1 Schematic representation of Nrf2 and Keap1 protein domains ENSG00000178573 ENSG00000079999 PMC9634729__F1 Targeting DNA damage response as a potential therapeutic strategy for head and neck squamous cell carcinoma ENSG00000012048 ENSG00000113318 ENSG00000095002 ENSG00000138385 PMC5643752__F2 Hinge-latch model of Nrf2 ENSG00000181019 ENSG00000178573 ENSG00000177606 ENSG00000079999 PMC4905289__F2 TGFB signaling ENSG00000153944 ENSG00000241186 PMC5629438__F3 Intracellular and Extracellular mode of Toll‐like receptor (TLR) signalling pathways: signalling heterogeneity in TLR pathways arises from the differential recognition of pathogen‐associated molecular patterns (PAMPs) by different TLRs ENSG00000150455 ENSG00000183735 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000172005 ENSG00000134070 ENSG00000157625 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC4086146__F1 Schematic model of mammalian heme homeostasis ENSG00000066926 ENSG00000156273 PMC11755879__F1 Molecular mechanisms of NLRC5 regulation of NFKB and type I IFN pathways and MHC I gene expression ENSG00000064490 ENSG00000183735 ENSG00000088888 ENSG00000115415 ENSG00000125347 PMC11755879__F2 Functions of NLRC5-dependent domains ENSG00000197471 ENSG00000168610 ENSG00000169375 PMC2900209__F6 Inflammation Stages in the Acute Lung Injury in Mice ENSG00000100591 ENSG00000109320 ENSG00000065559 ENSG00000155903 ENSG00000169032 ENSG00000127191 ENSG00000169967 ENSG00000104814 ENSG00000149269 ENSG00000170275 ENSG00000177606 ENSG00000175104 ENSG00000077782 PMC11755879__F3 NLRC5 in cancer ENSG00000162761 ENSG00000168036 ENSG00000112715 PMC3944192__F1 Kidney Regeneration: Common Themes From the Embryo to the Adult ENSG00000162552 ENSG00000103449 ENSG00000188064 ENSG00000075891 ENSG00000276799 PMC9614744__F7 Shared mechanisms and crosstalk of COVID-19 and osteoporosis via vitamin D ENSG00000169291 ENSG00000002330 ENSG00000110395 ENSG00000138798 ENSG00000177606 ENSG00000136997 PMC9614744__F8 Shared mechanisms and crosstalk of COVID-19 and osteoporosis via vitamin D ENSG00000087095 ENSG00000101474 ENSG00000069482 ENSG00000108684 ENSG00000170458 ENSG00000130159 ENSG00000175104 ENSG00000127191 ENSG00000026103 PMC6314413__F3 Representative Wzx/Wzy-dependent capsular polysaccharide (CPS) biosynthesis pathway in the group B streptococcal serotype III ENSG00000069482 ENSG00000153130 PMC6916502__F7 Proposed mechanisms for panx1 regulating ferroptosis in renal IR injury ENSG00000167996 ENSG00000110218 PMC9136161__F2 Degradative and Non-Degradative Roles of Autophagy Proteins in Metabolism and Metabolic Diseases ENSG00000265808 ENSG00000099940 PMC11625861__F1 The HS biosynthetic pathway ENSG00000138604 ENSG00000153936 ENSG00000182197 ENSG00000176022 ENSG00000285395 ENSG00000151348 PMC11765393__F1 Insulin signaling pathway in a healthy human brain ENSG00000169291 ENSG00000169047 ENSG00000198793 ENSG00000106459 PMC9084498__F1 Caffeoylquinic acids: chemistry, biosynthesis, occurrence, analytical challenges, and bioactivity ENSG00000062485 PMC4807882__F3 A Review of Systemic Treatment in Metastatic Triple-Negative Breast Cancer ENSG00000163464 ENSG00000291971 ENSG00000163599 ENSG00000138798 ENSG00000198793 PMC9181737__F2 Molecular Insight into the Therapeutic Effects of Stem Cell-Derived Exosomes in Respiratory Diseases and the Potential for Pulmonary Delivery ENSG00000104365 ENSG00000136869 PMC9019758__F9 Bushen Culuan Decoction Ameliorates Premature Ovarian Insufficiency by Acting on the Nrf2/ARE Signaling Pathway to Alleviate Oxidative Stress ENSG00000178573 ENSG00000172005 ENSG00000120885 ENSG00000156273 PMC7969947__F3 Non-secretory multiple myeloma with unusual TFG-ALK fusion showed dramatic response to ALK inhibition ENSG00000198793 PMC8864737__F3 WormPaths: Caenorhabditis elegans metabolic pathway annotation and visualization PMC4280296__F1 Alternative functions of the brain transsulfuration pathway represent an underappreciated aspect of brain redox biochemistry with significant potential for therapeutic engagement ENSG00000116984 PMC6014344__F4 Cross-link between TGFB pathway, Wnt pathway, and ILK pathway ENSG00000105329 ENSG00000134982 PMC7976506__AF1 Targeting the AnxA1/Fpr2/ALX pathway regulates neutrophil function, promoting thromboinflammation resolution in sickle cell disease ENSG00000122966 PMC6014344__F2 Molecular mechanisms involved in induction and progression of podocyte EMT caused by hyperglycemia ENSG00000168036 ENSG00000084774 PMC6014344__F3 TGFB/Smad classic pathway ENSG00000157933 PMC8864737__F2 WormPaths: Caenorhabditis elegans metabolic pathway annotation and visualization ENSG00000083857 ENSG00000104899 ENSG00000110711 ENSG00000165323 ENSG00000124253 ENSG00000131828 ENSG00000129744 PMC8107416__F1 DHODH and cancer: promising prospects to be explored ENSG00000102967 ENSG00000084774 ENSG00000254550 PMC7969441__F3 Telomere signaling pathway linking DNA damage response (DDR) and activation of ATM/ATR kinase, cycle arrest, and initiation of DNA damage ENSG00000149311 ENSG00000175054 ENSG00000128513 PMC4705829__F1 Signaling crosstalk between the mTOR complexes ENSG00000101407 ENSG00000163435 ENSG00000101751 ENSG00000198793 ENSG00000169047 ENSG00000145979 ENSG00000284161 ENSG00000155792 ENSG00000164327 ENSG00000179632 ENSG00000167965 PMC3827841__F6 TGFB and NOTCH activation in AoSMCs stimulated with P ENSG00000114315 PMC9569545__F1 Mitochondrial DNA Repair in Neurodegenerative Diseases and Ageing ENSG00000116688 ENSG00000171109 ENSG00000138385 PMC3827841__F3 Protein-protein interaction network and SPIA analysis of the 28 up-regulated genes related to positive regulation of cell proliferation and 21 down- regulated genes related to negative control of cell proliferation ENSG00000135547 ENSG00000105329 ENSG00000196839 ENSG00000113070 ENSG00000148926 ENSG00000124766 ENSG00000090776 ENSG00000162772 ENSG00000136826 ENSG00000064300 ENSG00000197461 ENSG00000157368 ENSG00000121068 ENSG00000292234 ENSG00000168398 ENSG00000171951 ENSG00000140464 PMC8365418__F10 Study of the pathology and the underlying molecular mechanism of tissue injury around hematoma following intracerebral hemorrhage ENSG00000139352 ENSG00000064300 PMC7298859__F7 TNFA/TNFR2 immune checkpoint signaling pathway could be used to target different aspects of tumor cells micro environment PMC1235815__F7 Possible ATM pathways contributing to polyomavirus replication (see Discussion) ENSG00000149311 ENSG00000012048 ENSG00000123374 ENSG00000166278 PMC3796519__F6 IL-27 Enhances the Expression of TRAIL and TLR3 in Human Melanomas and Inhibits Their Tumor Growth in Cooperation with a TLR3 Agonist Poly(I:C) Partly in a TRAIL-Dependent Manner ENSG00000115415 ENSG00000168610 ENSG00000164342 PMC3879613__F7 Biological functions regulated by miR-378 and miR-378* PMC9292677__F1 Uncovering the ‘sphinx’ of sphingosine 1‐phosphate signalling: from cellular events to organ morphogenesis ENSG00000063176 PMC9292677__F2 Uncovering the ‘sphinx’ of sphingosine 1‐phosphate signalling: from cellular events to organ morphogenesis ENSG00000038382 ENSG00000215021 ENSG00000019991 ENSG00000135363 ENSG00000127191 PMC9292677__F4 Uncovering the ‘sphinx’ of sphingosine 1‐phosphate signalling: from cellular events to organ morphogenesis ENSG00000162337 ENSG00000168036 ENSG00000170989 ENSG00000213694 ENSG00000131196 ENSG00000267534 ENSG00000183018 PMC5167996__F7 A model on how BLM complex promotes FANCM recruitment to stalled forks and replication traverse of ICLs ENSG00000175054 ENSG00000187790 ENSG00000197299 PMC8201988__F5 Integrative Ranking of Enhancer Networks Facilitates the Discovery of Epigenetic Markers in Cancer ENSG00000135446 ENSG00000138798 ENSG00000115718 ENSG00000146648 ENSG00000122008 PMC3077922__F3 Gene expression changes in response to zebularine therapy in vivo ENSG00000196975 ENSG00000170860 ENSG00000044115 ENSG00000136937 ENSG00000162244 ENSG00000171202 ENSG00000126756 ENSG00000143198 ENSG00000127511 ENSG00000153827 ENSG00000291973 ENSG00000215021 ENSG00000136997 ENSG00000284254 ENSG00000154059 ENSG00000139289 ENSG00000277258 ENSG00000134255 ENSG00000135250 PMC5226641__F1 Dysregulation of MicroRNA Biogenesis Machinery in Cancer ENSG00000124571 ENSG00000128191 ENSG00000113360 ENSG00000132341 PMC6606799__F2 Temporal changes in the transcriptome related to the central metabolic pathway in a synchronized C ENSG00000172005 PMC7461813__F2 TM4SF1 promotes the development and migration of cancer cells ENSG00000004975 ENSG00000169908 ENSG00000170558 ENSG00000132646 ENSG00000198793 ENSG00000168036 ENSG00000114948 ENSG00000112715 ENSG00000168610 PMC7409344__F3 eIF4B can stimulate eIF4A ENSG00000168036 PMC7312067__F1 MITOL regulates both RIG-I-like receptor (RLR) pathway and Toll-like receptor (TLR) pathway; (B) Relativity between MITOL and cell death signaling in cancer cells ENSG00000088888 ENSG00000172936 ENSG00000184216 PMC7409344__F2 eIF3 consists of the conserved eIF3a, eIF3b, eiF3c and the less conserved eIF3e, eIF3f, eIF3h subunits ENSG00000184110 ENSG00000198793 ENSG00000106263 ENSG00000175390 ENSG00000104408 ENSG00000107581 PMC4320988__F1 Molecular Pathways: Linking Tumor Microenvironment to Epithelial–Mesenchymal Transition in Metastasis ENSG00000169554 ENSG00000162733 ENSG00000122691 ENSG00000026508 ENSG00000168610 PMC6062828__F2 Presynaptic homeostatic functions of calcineurin (CaN) PMC9356669__F6 Targeting autophagy regulation in NLRP3 inflammasome-mediated lung inflammation in COVID-19 ENSG00000162711 ENSG00000213928 ENSG00000088888 ENSG00000130234 ENSG00000184012 ENSG00000136869 ENSG00000175104 ENSG00000276561 PMC8555221__F2 Systematic review of proteomic biomarkers in oral squamous cell cancer ENSG00000135446 ENSG00000105810 PMC8903576__F11 Peptidylarginine deiminase 2 promotes T helper 17-like T cell activation and activated T cell-autonomous death (ACAD) through an endoplasmic reticulum stress and autophagy coupling mechanism ENSG00000128272 ENSG00000144895 ENSG00000198793 ENSG00000168610 PMC6260243__F4 JAK1 may be the target molecule of (+)-terrein in the IL-6 signaling pathway in HGFs ENSG00000184371 ENSG00000112715 ENSG00000168610 PMC3681875__F7 Novel Chk1 inhibitor MK-8776 sensitizes human leukemia cells to HDAC inhibitors by targeting the intra-S checkpoint and DNA replication and repair ENSG00000012048 ENSG00000167513 ENSG00000123374 PMC8487948__F1 WNT signaling pathway ENSG00000281324 ENSG00000116729 ENSG00000162337 ENSG00000134982 ENSG00000133067 ENSG00000102312 ENSG00000183579 ENSG00000108375 PMC6056413__F7 Schematic diagram showing proposed pathway through which cyclic mechanical loading regulates primary cilia expression to control tendon matrix turnover ENSG00000094631 PMC5290160__F7 MYC-mediated mRNA cap methylation of Wnt/Beta-catenin signaling pathway transcripts ENSG00000101751 ENSG00000136997 ENSG00000101654 ENSG00000277273 ENSG00000196367 PMC10850749__S1 Garcinone C attenuates RANKL-induced osteoclast differentiation and oxidative stress by activating Nrf2/HO-1 and inhibiting the NF-kB signaling pathway ENSG00000100985 ENSG00000131196 ENSG00000143387 PMC8487948__F4 Targeting the WNT pathway- inhibitors in clinical trial ENSG00000281324 ENSG00000116729 ENSG00000162337 ENSG00000134982 ENSG00000133067 ENSG00000102312 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000173273 PMC8870278__F3 Mitophagy in Viral Infection ENSG00000162711 ENSG00000088888 ENSG00000057663 PMC5343325__F5 Jak-STAT signaling pathway ENSG00000110395 ENSG00000137193 PMC5343325__F3 P53 signaling pathway ENSG00000149311 ENSG00000175054 ENSG00000197872 ENSG00000002330 ENSG00000136997 ENSG00000123374 ENSG00000164305 PMC5343325__F4 TGFB signaling pathway ENSG00000049323 ENSG00000170365 ENSG00000111537 ENSG00000095739 ENSG00000100387 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000137801 PMC3362516__F1 Mitochondrial Ca2+ influx and efflux mechanisms ENSG00000107745 ENSG00000116688 ENSG00000156026 ENSG00000168924 PMC5343325__F2 MAPK signaling pathway ENSG00000087095 ENSG00000172680 ENSG00000170458 ENSG00000130159 ENSG00000127191 ENSG00000196712 ENSG00000026103 PMC4590606__F13 Model of T3-induced hepatic mitophagy ENSG00000177169 ENSG00000150907 ENSG00000198793 ENSG00000284099 ENSG00000110931 ENSG00000141564 ENSG00000132356 PMC7462335__F5 Exploring New Therapeutic Pathways in Pulmonary Hypertension. Metabolism, Proliferation, and Personalized Medicine ENSG00000142192 ENSG00000105329 ENSG00000138798 ENSG00000198793 ENSG00000198576 ENSG00000164362 ENSG00000168610 ENSG00000146648 PMC6620530__F2 Highlights of tumor metabolism ENSG00000228716 ENSG00000130164 ENSG00000136997 ENSG00000113161 ENSG00000169710 ENSG00000115419 ENSG00000159399 PMC7576358__F9 Mechanism of forsythin protecting RPE cells from apoptosis induced by hydrogen peroxide through the Nrf2 signaling pathway ENSG00000181019 ENSG00000079999 PMC6279568__F5 Resistance to MET and MET/MAPK/ERK inhibition in DFCI358 ENSG00000169291 ENSG00000169047 ENSG00000168610 ENSG00000146648 ENSG00000140443 PMC7501145__F1 Nutrient Transporters by Metabolic and Environmental Stresses ENSG00000134982 ENSG00000159263 ENSG00000112246 PMC7097199__F2 Signal transduction by SUMO ENSG00000177606 ENSG00000128602 PMC4756895__F1 Metabolic pathways – (a) Metabolic pathway of phenylalanine; (b) Pathway of urea cycle ENSG00000036473 PMC4078227__F2 Hedgehog signal pathway ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC1948012__F10 Action for AICAR in human leukemia ALL cells ENSG00000198793 PMC9382309__F3 DDX5 and DDX17—multifaceted proteins in the regulation of tumorigenesis and tumor progression ENSG00000108654 PMC4370503__F1 Vitamin D Receptor Cdx-2 Polymorphism and Premenopausal Breast Cancer Risk in Southern Pakistani Patients ENSG00000165556 ENSG00000205221 PMC9489161__F2 Immunological and toxicological risk assessment of e-cigarettes ENSG00000125538 PMC7645269__F8 Fibrogenesis during skeletal muscle atrophy ENSG00000086991 ENSG00000076604 PMC3323758__F4 DNA base excision repair: A mechanism of trinucleotide repeat expansion PMC8534645__F2 Sirtuins as Interesting Players in the Course of HIV Infection and Comorbidities ENSG00000150907 ENSG00000169710 ENSG00000077463 ENSG00000096717 ENSG00000142082 PMC9101148__F2 Bioactive Compounds in Obesity: Metabolic Mechanism Focused on Inflammation ENSG00000115138 ENSG00000168610 ENSG00000196396 PMC4353731__F1 Treatment of heterotopic ossification through remote ATP hydrolysis ENSG00000262406 ENSG00000170365 ENSG00000005339 ENSG00000105329 ENSG00000139567 ENSG00000291748 ENSG00000163132 ENSG00000204217 ENSG00000121966 ENSG00000172201 PMC4065826__F2 MAP kinase signaling in SC plasticity ENSG00000108691 ENSG00000177606 ENSG00000132478 ENSG00000128342 PMC6146372__F3 Autophagic control of Toxoplasma gondii ENSG00000177169 ENSG00000111537 ENSG00000175104 ENSG00000146648 PMC4858865__F1 Overexpressed metabolic pathways in the infection ENSG00000186063 ENSG00000118520 PMC9069556__F2 Coronavirus Infection and Cholesterol Metabolism ENSG00000042832 ENSG00000138135 ENSG00000116133 ENSG00000172893 ENSG00000130234 PMC8305159__F5 Antimelanogenesis Effects of Theasinensin A ENSG00000107165 PMC11117611__F5 NEDD4 and NEDD4L: Ubiquitin Ligases Closely Related to Digestive Diseases ENSG00000136158 ENSG00000069869 ENSG00000198793 ENSG00000168610 ENSG00000131023 PMC11117611__F6 NEDD4 and NEDD4L: Ubiquitin Ligases Closely Related to Digestive Diseases ENSG00000182718 ENSG00000069869 ENSG00000265972 ENSG00000140443 PMC9382309__F4 DDX5 and DDX17—multifaceted proteins in the regulation of tumorigenesis and tumor progression ENSG00000134982 ENSG00000173039 ENSG00000168036 ENSG00000108654 ENSG00000196628 PMC3372922__F2 Action of TIEG in the TGFBeta-Smad signaling pathway PMC11117611__F3 NEDD4 and NEDD4L: Ubiquitin Ligases Closely Related to Digestive Diseases ENSG00000069869 ENSG00000140443 PMC11117611__F4 NEDD4 and NEDD4L: Ubiquitin Ligases Closely Related to Digestive Diseases ENSG00000100811 ENSG00000069869 ENSG00000136997 PMC9382309__F6 DDX5 and DDX17—multifaceted proteins in the regulation of tumorigenesis and tumor progression ENSG00000128191 ENSG00000113360 PMC7952134__F4 Bioinformatic pathway analysis of proteins with altered phosphorylation site occupancy in PPP2R5D E420K-variant cells.A, proteins associated with enriched KEGG pathways identified in F ENSG00000047410 ENSG00000198382 ENSG00000090402 ENSG00000134982 ENSG00000086589 ENSG00000205302 ENSG00000138443 ENSG00000198793 ENSG00000158195 ENSG00000155792 ENSG00000151693 ENSG00000073111 ENSG00000277273 ENSG00000231377 ENSG00000175054 ENSG00000107186 ENSG00000071051 ENSG00000114503 ENSG00000084112 ENSG00000205937 ENSG00000126458 ENSG00000140464 ENSG00000253729 ENSG00000126016 ENSG00000109061 ENSG00000169554 ENSG00000102900 ENSG00000213341 ENSG00000147274 ENSG00000160691 ENSG00000145604 ENSG00000186635 ENSG00000177606 ENSG00000115266 PMC7952134__F7 PPP2R5D E420K-variant signaling ENSG00000112640 ENSG00000168036 ENSG00000105723 ENSG00000140443 PMC7227035__F6 EGFR (a) and NFKB (b) pathway-focused RT-PCR gene expression analysis of representative TNBC PDX RNA samples collected before and after Pan-HER treatment ENSG00000104856 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000168610 PMC12081406__F1 Biosynthetic pathway of sphingosine 1-phosphate and related molecules ENSG00000100422 ENSG00000063176 ENSG00000102172 PMC11211685__F5 Fusarium mycotoxins: The major food contaminants PMC11211685__F4 Fusarium mycotoxins: The major food contaminants ENSG00000169554 PMC5961061__F1 Structures, enzymes, and reaction mechanisms of lipoic acid metabolism ENSG00000121897 ENSG00000090402 ENSG00000175536 ENSG00000107798 PMC4816652__F8 Long-term ERK Inhibition in KRAS-mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression ENSG00000121989 ENSG00000027075 ENSG00000100422 ENSG00000170365 ENSG00000141503 ENSG00000186716 ENSG00000137802 PMC8884272__F1 Intriguing Role of TLR Accessory Molecules in Cardiovascular Health and Disease ENSG00000174125 ENSG00000183735 ENSG00000135218 ENSG00000197386 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000255690 ENSG00000175104 ENSG00000184216 PMC8356007__F10 Exploring the Pharmacological Mechanism of Liuwei Dihuang Decoction for Diabetic Retinopathy: A Systematic Biological Strategy-Based Research ENSG00000150782 ENSG00000171105 ENSG00000111537 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000169710 ENSG00000171791 ENSG00000073756 ENSG00000146648 PMC3575666__F4 VPS4B downregulation increases the expression of mitochondrial fatty acid Beta-oxidation related proteins and down regulates the expression of glycolysis related proteins in SKBR3 cells ENSG00000131473 ENSG00000117054 ENSG00000074800 ENSG00000138029 ENSG00000169710 ENSG00000110435 ENSG00000146701 ENSG00000159399 ENSG00000101365 ENSG00000062485 PMC8356007__F11 Exploring the Pharmacological Mechanism of Liuwei Dihuang Decoction for Diabetic Retinopathy: A Systematic Biological Strategy-Based Research ENSG00000134086 ENSG00000069482 ENSG00000198793 ENSG00000072274 ENSG00000168610 PMC6113216__F7 RGMa regulation of TGFB1/Smad2/3 signaling in astrocytes ENSG00000182175 ENSG00000105329 ENSG00000131095 PMC8694403__F3 iTRAQ and PRM-Based Proteomic Analysis Provides New Insights into Mechanisms of Response to Triple Therapy in Patients with Rheumatoid Arthritis ENSG00000168003 ENSG00000134086 ENSG00000179091 ENSG00000196839 ENSG00000167468 ENSG00000072274 ENSG00000111684 ENSG00000145321 ENSG00000136869 ENSG00000168610 ENSG00000115107 ENSG00000057663 PMC9246651__F1 Cellular communication network factor 1 by Ras homolog family member A in bovine steroidogenic luteal cells ENSG00000138039 ENSG00000150457 ENSG00000131023 PMC10040775__F5 Low-protein maternal diet during gestation affects the expression of key pancreatic Beta-cell genes and the methylation status of the regulatory region of the MafA gene in the offspring of Wistar rats ENSG00000177606 ENSG00000162772 ENSG00000132170 PMC3708799__F2 PTEN in Beta-Cell Growth ENSG00000002330 ENSG00000198793 ENSG00000026103 PMC8349889__F7 Gene regulation by EGR1 in ABC DLBCL ENSG00000141867 ENSG00000105397 ENSG00000115415 ENSG00000186716 ENSG00000136997 ENSG00000166886 ENSG00000276561 ENSG00000010671 PMC7110906__F1 PI3K/AKT/mTOR signalling pathway ENSG00000163435 ENSG00000002330 ENSG00000198793 ENSG00000155792 PMC8577020__F1 P53 family member p73 in the regulation of cell stress response ENSG00000149311 ENSG00000175054 ENSG00000134057 ENSG00000051180 ENSG00000116717 ENSG00000131143 ENSG00000139618 PMC8326120__F1 Non-shivering Thermogenesis Signalling Regulation and Potential Therapeutic Applications of Brown Adipose Tissue ENSG00000157500 ENSG00000164430 ENSG00000171720 ENSG00000042832 ENSG00000100219 ENSG00000096717 PMC9428205__F7 Potential regulatory mechanism of inhibiting autophagy to enhance the cytotoxicity of FIIN-2 on A549 and A549/DDP cells ENSG00000198793 PMC8326120__F2 Non-shivering Thermogenesis Signalling Regulation and Potential Therapeutic Applications of Brown Adipose Tissue ENSG00000042832 ENSG00000145321 PMC8326120__F3 Non-shivering Thermogenesis Signalling Regulation and Potential Therapeutic Applications of Brown Adipose Tissue ENSG00000042832 ENSG00000142611 ENSG00000116985 PMC8756491__F1 Biallelic variants in MESD, which encodes a WNT-signaling-related protein, in four new families with recessively inherited osteogenesis imperfecta ENSG00000281324 ENSG00000130164 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000117899 ENSG00000277641 ENSG00000125084 PMC8326120__F4 Non-shivering Thermogenesis Signalling Regulation and Potential Therapeutic Applications of Brown Adipose Tissue ENSG00000042832 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC8326120__F5 Non-shivering Thermogenesis Signalling Regulation and Potential Therapeutic Applications of Brown Adipose Tissue ENSG00000187688 ENSG00000042832 ENSG00000142611 ENSG00000145321 ENSG00000196689 PMC5241026__F8 RhoA inhibits neural differentiation in murine stem cells through multiple mechanisms ENSG00000131941 ENSG00000096717 PMC8577020__F5 P53 family member p73 in the regulation of cell stress response ENSG00000135423 ENSG00000092621 ENSG00000135069 PMC8714953__F1 Porcine Reproductive and Respiratory Syndrome Virus Evades Antiviral Innate Immunity via MicroRNAs Regulation ENSG00000213928 ENSG00000088888 ENSG00000115993 ENSG00000105397 ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC5597737__F1 Activation of NFKB and IL6/STAT3 signalling pathways in NPC cells by multiple EBV-encoded latent gene products ENSG00000104856 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000127191 ENSG00000168610 ENSG00000164342 PMC5149556__F1 Molecular events that connect inflammation to insulin resistance in obesity ENSG00000183735 ENSG00000102871 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000127191 PMC6366304__F2 Common nodes of resistance to targeted therapies within the PI3K pathway ENSG00000109452 ENSG00000157764 ENSG00000105647 ENSG00000121879 ENSG00000146648 PMC6638189__F1 Overview of RNAi pathways in aedine mosquitoes ENSG00000092847 ENSG00000113360 ENSG00000123908 PMC6366304__F3 Targeting the PI3K pathway in cancer with small-molecule inhibitors ENSG00000171105 ENSG00000169047 PMC5453110__F1 IL-8/IL-8R axis ENSG00000163464 ENSG00000291971 ENSG00000168036 PMC4951400__F4 Classification of Colon Cancer Patients Based on the Methylation Patterns of Promoters ENSG00000276825 ENSG00000164742 ENSG00000162337 ENSG00000169676 ENSG00000291971 ENSG00000198793 ENSG00000152785 ENSG00000128602 ENSG00000277641 ENSG00000149295 PMC6906312__F6 Ingenuity Pathway Analysis (IPA) of differential metabolites in POD 7 between GIK and TPN ENSG00000101280 PMC3213398__F7 Working Model for the Late-Acting Function of NFU1 in Mitochondrial Fe-S Protein BiogenesisThe findings of this work suggest a late-acting function of NFU1 in the pathway of Fe-S (red and yellow circles) protein maturation ENSG00000136003 ENSG00000169599 ENSG00000135070 PMC6993496__F6 Positional relationships of CDKN3-associated genes in the cell cycle ENSG00000145604 ENSG00000094804 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000205250 ENSG00000277273 ENSG00000276876 PMC8810313__F1 Viral deubiquitinases and innate antiviral immune response in livestock and poultry ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000187608 ENSG00000102007 ENSG00000131323 ENSG00000175104 ENSG00000276561 PMC6675602__F7 Pterostilbene (PTS) prevented ROS formation and reversed palmitic acid (PA) mediated increase in hepatic glucose production by reducing expression of genes coding for gluconeogenic enzymes and their transcription factors ENSG00000173599 PMC6604150__F3 Differentially expressed genes were labeled in the proteoglycans in cancer pathway in the placenta after IVF-ET during the first trimester by KEGG ENSG00000100234 ENSG00000175193 ENSG00000163914 ENSG00000198517 ENSG00000128602 ENSG00000146648 PMC3315368__F4 Gene Array Data from CWR22RV1 xenografts treated with PD325901 for three weeks ENSG00000172680 ENSG00000138798 ENSG00000144118 ENSG00000146648 ENSG00000196712 PMC9497767__F4 Epithelial–Mesenchymal Transition by Synergy between Transforming Growth FactorB and Growth Factors in Cancer Progression ENSG00000169554 ENSG00000026508 ENSG00000104413 PMC8904967__F2 Cystine/Glutamate Antiporter SLC7A11/xCT in the Pathophysiology of Cancer ENSG00000151012 ENSG00000167468 PMC3835685__F1 Human epidermal growth fa ctor receptor 2 (HER2) signal transduction pathways ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000198793 ENSG00000158458 ENSG00000132478 ENSG00000169752 PMC11542427__F3 Shows that, owing to aging, there is an increased release of proinflammatory adipokines that stimulate the activation of TNF, TGFBR, and insulin receptors ENSG00000177169 ENSG00000134982 ENSG00000150907 ENSG00000168036 PMC4657121__F1 Amino acid metabolic pathways targeted in cancer therapy ENSG00000284320 ENSG00000135423 ENSG00000092621 ENSG00000060982 ENSG00000129167 PMC6812767__F8 Assessing the role of toll-like receptor in isolated, standard and enriched housing conditions ENSG00000174123 ENSG00000243414 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000127666 ENSG00000164342 PMC6397079__F7 The effect of miR-15a-5p on MK GPVI signaling ENSG00000010810 ENSG00000197943 ENSG00000132693 PMC8542908__F3 Telomere Signaling and Maintenance Pathways in Spermatozoa of Infertile Men Treated With Antioxidants: An in silico Approach Using Bioinformatic Analysis ENSG00000136997 ENSG00000146648 ENSG00000139687 ENSG00000140416 PMC7646179__F1 FGF/FGFR signaling pathway ENSG00000142192 ENSG00000198793 PMC11275499__F1 Antidepressant potential of ghrelin, which exerts neuroprotective effects by promoting neuronal proliferation and neurotrophic factor production in the brain ENSG00000198793 ENSG00000168036 ENSG00000168610 PMC5852553__F10 Actin cytoskeleton signaling pathway in Cobb chickens ENSG00000038382 ENSG00000172380 ENSG00000175866 ENSG00000198408 ENSG00000134982 ENSG00000138443 ENSG00000138798 ENSG00000089159 PMC4599016__F5 Two separate GA13 Switch Region signaling pathways ENSG00000047410 ENSG00000075142 PMC4442437__F10 Schematic of proposed mechanism for CpG-induced enhancement of the transepithelial transport of H9N2 WIV in nasal mucosa ENSG00000239732 ENSG00000115009 PMC2912657__F1 NFKB activation pathways ENSG00000162924 PMC8593035__F7 Mechanism of NUSAP1 promoting DNA repair process by binding with RAD51 ENSG00000149311 ENSG00000137804 ENSG00000051180 ENSG00000139618 PMC11917137__F7 Schematic model for the mechanism and role of HOGA1 in ccRCC ENSG00000241935 ENSG00000168036 PMC3670289__F3 Differential STAT3 signaling in the heart ENSG00000140992 ENSG00000168610 PMC8582810__F7 Bcl-2 Modulation in p53 Signaling Pathway by Flavonoids: A Potential Strategy towards the Treatment of Cancer PMC6456510__F5 Possible regulatory association of miRNA let-7-related gene networks ENSG00000166135 PMC4605443__F2 The TREM2-DAP12 signaling pathway in Nasu–Hakola disease: a molecular genetics perspective ENSG00000146094 ENSG00000172936 ENSG00000135605 PMC4520659__F4 Cellular and molecular determinants of all-trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARA expression ENSG00000143320 PMC7545926__F8 Schematical representation of the protective mechanism of H2O2 preconditioning for improving the therapeutic potential of BMSCs ENSG00000198793 ENSG00000121966 PMC4605443__F1 The TREM2-DAP12 signaling pathway in Nasu–Hakola disease: a molecular genetics perspective ENSG00000187796 ENSG00000291971 ENSG00000115904 ENSG00000168036 ENSG00000135605 PMC5036923__F1 The IMD pathway and its regulation by Die and WntD ENSG00000174804 ENSG00000168040 PMC6366304__F1 Common PI3K pathway aberrations found in a variety of solid tumor types ENSG00000066468 ENSG00000109452 ENSG00000121879 PMC8995746__F1 Targeting NLRP3 Inflammasome With Nrf2 Inducers in Central Nervous System Disorders ENSG00000162711 ENSG00000178573 ENSG00000265972 ENSG00000079999 PMC8323235__F9 ESCRT-0 subcomplex component Hrs/Hgs is a master regulator of myogenesis via modulation of signaling and degradation pathways ENSG00000150907 ENSG00000169047 ENSG00000146648 PMC6001480__F3 Functional networks in mucinous type epithelial ovarian cancer ENSG00000005175 ENSG00000116161 ENSG00000189337 ENSG00000066044 ENSG00000118898 ENSG00000205220 ENSG00000230034 ENSG00000100603 PMC9476644__F3 Curcumin's prevention of inflammation-driven early gastric cancer and its molecular mechanism ENSG00000154342 ENSG00000281324 ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC5115347__F1 The degranulatory signaling cascade of RBL‐2H3 (adapted from refs ENSG00000213658 PMC7539839__F1 Mitochondrial roles in health and disease ENSG00000182511 ENSG00000116688 ENSG00000158828 ENSG00000171109 PMC8324678__F3 Hepatic lipid droplets: A balancing act between energy storage and metabolic dysfunction in NAFLD ENSG00000213996 ENSG00000100344 ENSG00000273592 PMC5294487__F1 Steroid hormone synthesis and endogenous oestrogen metabolism in humans ENSG00000140465 PMC3350790__F1 Dmrt genes integrate sex-specific, spatial, and temporal cues to induce sexually dimorphic differentiation in restricted groups of cells ENSG00000163914 ENSG00000141968 PMC4589549__F4 Canonical Wnt pathway illustrating the roles of PITX2 dependant genes ENSG00000281324 ENSG00000134982 ENSG00000104371 ENSG00000136997 ENSG00000026508 ENSG00000168036 ENSG00000164093 ENSG00000140807 PMC2633299__F11 UVB light upregulates prostaglandin synthases and prostaglandin receptors in mouse keratinocytes ENSG00000291791 ENSG00000182621 PMC3081620__F1 Representative cascade of the TGFB pathway PMC5645534__F2 Overall survival mechanism used by the Apicomplexan parasites in different host cells ENSG00000019991 ENSG00000002330 ENSG00000042832 ENSG00000291971 ENSG00000198793 ENSG00000171791 ENSG00000100985 ENSG00000127191 ENSG00000168610 ENSG00000146648 PMC2394768__F4 Network diagram comprising genes and functional processes associated with regulated AS events in the CNS ENSG00000163914 ENSG00000131018 ENSG00000196586 ENSG00000114738 PMC6269430__F5 General mechanism of Wnt induction ENSG00000168283 ENSG00000198901 ENSG00000291527 PMC2757291__F6 The SLAM-Associated Protein (SAP)/Fyn/PKCθ Pathway is Required for Thymocyte-mediated CD4 T Cell Development ENSG00000134982 ENSG00000010810 ENSG00000135605 PMC8290884__F2 Selective Neuron Vulnerability in Common and Rare Diseases—Mitochondria in the Focus ENSG00000172680 ENSG00000123240 ENSG00000116688 ENSG00000158828 ENSG00000069329 ENSG00000104381 PMC8910853__F3 Aldehyde Dehydrogenase 2 as a Therapeutic Target in Oxidative Stress-Related Diseases: Post-Translational Modifications Deserve More Attention ENSG00000105329 ENSG00000096717 PMC11765076__F1 Aerobic glycolysis in cancer PMC8618899__SF1 Time-Dependent Changes in Hepatic Sphingolipid Accumulation and PI3K/Akt/mTOR Signaling Pathway in a Rat Model of NAFLD ENSG00000063176 ENSG00000002330 ENSG00000100596 ENSG00000198793 ENSG00000188611 ENSG00000102172 ENSG00000105723 PMC3416606__F1 Central carbon metabolism in S ENSG00000074800 ENSG00000100412 ENSG00000146701 ENSG00000275544 PMC11765076__F2 Pentose phosphate pathway and its connections with our metabolic pathways ENSG00000197713 ENSG00000153574 PMC7491459__F3 Schematic diagram sketching three well-characterized pathways (3 vertical lanes) in which TGFB plays a role via signaling and/or transactivation/crosstalk and which may act to promote or prevent hypertension ENSG00000105329 ENSG00000113070 ENSG00000135966 ENSG00000138080 ENSG00000146648 PMC4130844__F1 Signal transduction and immune response in Helicobacter pylori infected gastric epithelial cells ENSG00000291971 ENSG00000149269 ENSG00000177606 ENSG00000136869 ENSG00000106100 ENSG00000167701 PMC11765076__F4 Serine metabolism pathway ENSG00000284320 ENSG00000228716 ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC6695959__F1 DNAM-1 signaling pathway leading to natural killer (NK) cell activation ENSG00000130202 ENSG00000153283 ENSG00000181847 ENSG00000010810 ENSG00000141968 PMC11765076__F5 Proline metabolism pathway ENSG00000100033 PMC11765076__F6 Tricarboxylic acid (TCA) cycle or Krebs cycle ENSG00000143252 ENSG00000073578 ENSG00000100412 ENSG00000117118 ENSG00000163541 ENSG00000105953 ENSG00000172340 ENSG00000146701 ENSG00000091140 ENSG00000101365 ENSG00000062485 PMC5398979__F2 Pathway alterations in glioblastoma ENSG00000157764 ENSG00000135446 ENSG00000134853 ENSG00000105810 ENSG00000146648 ENSG00000139687 ENSG00000196712 ENSG00000198625 PMC10344634__F10 Graphical abstract ENSG00000168090 ENSG00000170558 PMC8324678__F1 Hepatic lipid droplets: A balancing act between energy storage and metabolic dysfunction in NAFLD ENSG00000173599 ENSG00000198670 PMC7283464__F2 Enteroviruses regulate apoptosis through the PI3K/AKT pathway ENSG00000002330 PMC9107190__F9 Label-free LC–MS/MS proteomics analyses reveal proteomic changes in oxidative stress and the SOD antioxidant strategy in TM cells ENSG00000087245 ENSG00000127445 ENSG00000007908 PMC9219453__F5 Relationship between Plasma Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Level and Proteome Profile of Cows ENSG00000078549 ENSG00000172831 ENSG00000274619 ENSG00000138207 ENSG00000114113 ENSG00000288369 ENSG00000072274 ENSG00000000971 ENSG00000087460 ENSG00000114115 ENSG00000186469 PMC8037268__F17 Signaling pathways affected by hSDC1 overexpression in DEN-induced hepatocarcinogenesis ENSG00000167601 ENSG00000115884 ENSG00000171105 ENSG00000134982 ENSG00000113070 ENSG00000155792 ENSG00000168036 ENSG00000162924 ENSG00000146648 PMC7174595__F1 Lysophosphatidic acid (LPA) as a promoter in Alzheimer’s disease (AD) related neurodegeneration ENSG00000132906 ENSG00000002330 ENSG00000163914 ENSG00000198670 ENSG00000164305 PMC9650365__F1 Crosstalk among autophagy, apoptosis, and pyroptosis in cardiovascular disease ENSG00000177169 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC7466743__F5 Targeting the CLL/MSC crosstalk using CXCR4/CXCL12 and BCR signaling inhibitors ENSG00000178860 ENSG00000107562 ENSG00000186716 ENSG00000171791 ENSG00000121966 PMC3946676__F1 Changing appetites: The adaptive advantages of fuel choice ENSG00000175054 ENSG00000092621 ENSG00000115419 ENSG00000026103 PMC3946676__F2 Changing appetites: The adaptive advantages of fuel choice ENSG00000284320 ENSG00000065911 ENSG00000100714 ENSG00000092621 ENSG00000120254 PMC5354934__F3 Anti-tumor activity of metformin: from metabolic and epigenetic perspectives ENSG00000198793 PMC8169546__F1 The Protective Mechanisms of Paeoniflorin in Neurological, Cardiovascular, and Renal Diseases ENSG00000168610 ENSG00000146648 ENSG00000079999 PMC6471792__F3 Hypothetical G protein-coupled receptor (GPCR) heterodimeric T1R2/T1R3 taste receptors exist in a multimeric receptor complex with NMBR, IRB, and Neu-1 in naïve IR expressing cells ENSG00000169047 ENSG00000100985 ENSG00000135577 PMC9392712__F4 Targeting autophagy as a therapeutic strategy against pancreatic cancer ENSG00000125166 ENSG00000065833 ENSG00000197713 ENSG00000122966 ENSG00000172005 ENSG00000153574 ENSG00000166123 ENSG00000115419 ENSG00000159399 PMC7504001__F10 Schematic picture proposing that OXY modulates the IL-1Beta-stimulated inflammatory response ENSG00000175104 ENSG00000184216 PMC3442893__F1 Proline dehydrogenase (oxidase), a mitochondrial tumor suppressor, and autophagy under the hypoxia microenvironment ENSG00000126775 ENSG00000196455 ENSG00000198793 ENSG00000100033 PMC9392712__F2 Targeting autophagy as a therapeutic strategy against pancreatic cancer ENSG00000177169 ENSG00000123395 ENSG00000126775 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC3680918__F6 Schematic diagram of the PIP signaling pathway in ER-negative breast cancer ENSG00000150093 PMC8308509__F3 Hypomethylating Chemotherapeutic Agents as Therapy for Myelodysplastic Syndromes and Prevention of Acute Myeloid Leukemia ENSG00000019991 ENSG00000185591 ENSG00000253729 PMC5076460__F6 Global gene profiling of aging lungs in Atp8b1 mutant mice ENSG00000005339 ENSG00000160808 ENSG00000198125 PMC5076460__F4 Global gene profiling of aging lungs in Atp8b1 mutant mice ENSG00000117525 ENSG00000005339 ENSG00000198125 ENSG00000171608 ENSG00000139687 PMC5076460__F5 Global gene profiling of aging lungs in Atp8b1 mutant mice ENSG00000157087 ENSG00000070961 ENSG00000198125 PMC6823401__F10 Figure shows an MPR route that gets activated by the stimulation of progesterone receptor and has a role in cell proliferation by upregulation of PKA/cAMP by the activation of CREB/CREM/ATF-1 ENSG00000291971 ENSG00000168036 ENSG00000185591 ENSG00000168610 ENSG00000146648 PMC8657738__F4 Skin Aging, Cellular Senescence and Natural Polyphenols ENSG00000131473 ENSG00000065833 ENSG00000198670 ENSG00000115419 ENSG00000062485 PMC4826959__F1 Schematic representation of polycomb-repressive complex 2 inhibition mechanisms ENSG00000151376 PMC7765584__F4 Gene network interaction of cancer stem cell signaling pathway in (A) LNCaP cells and (B) C4-2B cells with and without enzalutamide treatment ENSG00000185386 ENSG00000136997 ENSG00000139269 ENSG00000174804 ENSG00000188130 ENSG00000283060 ENSG00000157240 PMC5920436__F1 BCR pathway activation ENSG00000105369 ENSG00000186716 ENSG00000198793 ENSG00000010671 PMC9557748__F5 Terpenoids and their gene regulatory networks in Opisthopappus taihangensis ‘Taihang Mingzhu’ as detected by transcriptome and metabolome analyses ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC7957739__F1 Dysregulation of signaling pathways by chronic viral hepatitis and epigenetic imprinting impact the secretion of circulating candidate biomarkers to the blood ENSG00000198793 ENSG00000081051 ENSG00000168610 ENSG00000146648 PMC6701341__F5 Circadian clock pathway mapped with relative expression levels (T1 vs ENSG00000148798 PMC4696776__F2A Insights into acute myeloid leukemia via single cell network profiling ENSG00000124102 ENSG00000197943 ENSG00000118777 ENSG00000121966 PMC8234087__F2 ChoK-Full of Potential: Choline Kinase in B Cell and T Cell Malignancies ENSG00000110721 ENSG00000117480 ENSG00000186716 ENSG00000179630 ENSG00000173599 ENSG00000136997 ENSG00000136869 ENSG00000153395 ENSG00000131323 ENSG00000161714 ENSG00000133027 PMC6950657__F1 Mechanisms underlying the life-extending and tumor-inhibiting effects of calorie restriction in mammals ENSG00000198793 ENSG00000140443 PMC9650365__F2 Crosstalk among autophagy, apoptosis, and pyroptosis in cardiovascular disease ENSG00000278718 ENSG00000162711 ENSG00000198793 ENSG00000005893 ENSG00000265972 ENSG00000096717 ENSG00000142082 PMC8190181__F1 Signaling pathways in cancer-associated fibroblasts and targeted therapy for cancer ENSG00000157933 ENSG00000140262 ENSG00000197081 ENSG00000137033 ENSG00000291971 ENSG00000124882 ENSG00000026508 ENSG00000198670 ENSG00000078098 ENSG00000168610 PMC5899973__F3 Bile acid–microbiota cross-talk in gastrointestinal inflammation and carcinogenesis ENSG00000196549 PMC5899973__F4 Bile acid–microbiota cross-talk in gastrointestinal inflammation and carcinogenesis ENSG00000111537 ENSG00000291971 ENSG00000125538 ENSG00000136997 PMC3653888__F3 Yin Yang 1 and Adipogenic Gene Network Expression in Longissimus Muscle of Beef Cattle in Response to Nutritional Management ENSG00000100811 ENSG00000137947 ENSG00000111537 ENSG00000173757 ENSG00000115461 ENSG00000114166 ENSG00000132170 PMC3252343__F4 Expression Signature of IFN/STAT1 Signaling Genes Predicts Poor Survival Outcome in Glioblastoma Multiforme in a Subtype-Specific Manner ENSG00000184979 ENSG00000275214 ENSG00000175376 ENSG00000187608 ENSG00000089127 ENSG00000115415 ENSG00000157601 ENSG00000185745 PMC3653888__F4 Summary of YY1 gene network expression in steers comparing early weaning (EWS) against normal weaning without creep feeding (NWN) at 240 days on treatment.Notes: Cellular locations depicted are from the Ingenuity Pathway Analysis® knowledge base ENSG00000100811 ENSG00000101751 ENSG00000173757 ENSG00000115461 ENSG00000114166 ENSG00000132170 PMC11601888__F4 Function analysis of the high-confidence functional lncRNAs ENSG00000156574 ENSG00000015285 ENSG00000168036 ENSG00000132341 PMC9069003__F3 Action of Ozone Therapy in Emerging Viral Diseases: Immunomodulatory Effects and Therapeutic Advantages With Reference to SARS-CoV-2 ENSG00000162711 ENSG00000178573 ENSG00000130234 ENSG00000125538 ENSG00000079999 PMC9069003__F4 Action of Ozone Therapy in Emerging Viral Diseases: Immunomodulatory Effects and Therapeutic Advantages With Reference to SARS-CoV-2 ENSG00000162711 ENSG00000130234 ENSG00000125538 ENSG00000079999 PMC7450930__F7 Distribution of the target proteins of Xiaochaihu decoction on the predicted pathways (The red nodes are potential target proteins of Xiaochaihu decoction, while the orange nodes are relevant targets in the pathway) ENSG00000087245 ENSG00000108691 ENSG00000171105 ENSG00000168036 ENSG00000132478 ENSG00000168610 PMC8835790__F1 Epigenetics in the Diagnosis and Therapy of Malignant Melanoma ENSG00000088826 ENSG00000170430 ENSG00000124275 ENSG00000118520 ENSG00000123505 ENSG00000116649 ENSG00000102172 ENSG00000276043 ENSG00000116984 PMC9213320__F1 Scaffold-dependent function of RIPK1 in experimental non-alcoholic steatohepatitis ENSG00000137275 ENSG00000102871 ENSG00000157625 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000164305 ENSG00000285379 PMC5397865__F8 Salt suppresses IFNG inducible chemokines through the IFNGamma-JAK1-STAT1 signaling pathway in proximal tubular cells ENSG00000169245 ENSG00000186810 ENSG00000159128 ENSG00000111537 ENSG00000115415 ENSG00000163739 ENSG00000138755 ENSG00000027697 PMC11753526__F6 Type I interferons attach to their receptors, causing tyrosine kinase 2 to phosphorylate tyrosine and activate STAT1 and STAT2 ENSG00000105397 PMC12241195__F5 Tackling Wnt signaling by the Wnt inhibitor SM04690 ENSG00000157540 ENSG00000134982 ENSG00000150907 ENSG00000116690 ENSG00000096717 PMC4511561__F5 Integrative Analysis of the Developing Postnatal Mouse Heart Transcriptome ENSG00000108055 ENSG00000135446 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000205250 ENSG00000105810 ENSG00000277273 ENSG00000276876 PMC8238877__F1 SARS-CoV-2 signals through TLR2 to activate proinflammatory cytokine expression ENSG00000169245 ENSG00000172936 PMC7539765__F5 Probable interactions among TRIP13 and other molecules within clear cell Renal Cell Carcinoma ENSG00000198793 ENSG00000114315 ENSG00000071539 PMC8586510__F2 Intertwined Signaling Pathways Governing Tooth Development: A Give-and-Take Between Canonical Wnt and Shh ENSG00000162552 ENSG00000157404 ENSG00000188064 ENSG00000169884 ENSG00000164093 ENSG00000164690 ENSG00000277641 PMC11753526__F2 Comprehensive examination of the Toll-like receptor 9 (TLR9)-mediated signaling pathway ENSG00000108691 ENSG00000172936 ENSG00000157625 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000115009 PMC6351931__F10 Schematic diagram of the signaling pathway relevant to HKMT-induced pleural fibrosis in pleural mesothelial cells (PMCs) ENSG00000086991 ENSG00000136869 PMC8534156__F3 Progress on Ras/MAPK Signaling Research and Targeting in Blood and Solid Cancers ENSG00000291971 PMC8534156__F5 Progress on Ras/MAPK Signaling Research and Targeting in Blood and Solid Cancers ENSG00000110395 ENSG00000291971 ENSG00000095321 PMC4367644__F1 IGF-1R Signaling Pathway ENSG00000002330 ENSG00000198793 ENSG00000140443 PMC4494900__F3 Emerging role of CaMKII in cancer ENSG00000156299 ENSG00000135446 PMC6833135__F3 Gene expression levels of central carbon metabolic pathways ENSG00000122966 ENSG00000100412 ENSG00000172005 ENSG00000146701 ENSG00000169299 PMC4541321__F2 Topologically inferring pathway activity toward precise cancer classification via integrating genomic and metabolomic data: prostate cancer as a case ENSG00000100033 PMC2448841__F5 Proposed model of arrest of maturation/activation of DCs via ILT4 receptor and HLA-G ligand ENSG00000276051 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000168610 PMC8672651__F1 Complement as driver of and therapeutic target in COVID-19 ENSG00000009724 ENSG00000291559 ENSG00000130234 ENSG00000288512 ENSG00000173039 ENSG00000117335 ENSG00000182326 PMC8570289__F1 Key Activating and Inhibitory Ligands Involved in the Mobilization of Natural Killer Cells for Cancer Immunotherapies ENSG00000291603 ENSG00000224320 ENSG00000117091 ENSG00000181847 ENSG00000010810 ENSG00000198793 ENSG00000141968 PMC11854242__F5 YAP-mediated gene expression in liver fibrosis ENSG00000291971 ENSG00000198670 ENSG00000150457 ENSG00000108821 ENSG00000131023 PMC11854242__F6 Mechanosignaling via Integrins: Pivotal Players in Liver Fibrosis Progression and Therapy ENSG00000291748 PMC11854242__F4 Rho/ROCK/MRTF/SRF transcription pathway and its upstream regulation by the actin cytoskeleton in liver fibrosis ENSG00000291971 ENSG00000198670 ENSG00000067900 ENSG00000108821 PMC9037381__F2 Pathogenic Mechanisms of Fusobacterium nucleatum on Oral Epithelial Cells ENSG00000124216 PMC5625807__F2 Genes identified from the enrichment analysis were significantly associated with OSA comorbidities ENSG00000186090 ENSG00000151617 ENSG00000102468 PMC8102094__F3 Positive and Negative Regulation of Ferroptosis and Its Role in Maintaining Metabolic and Redox Homeostasis ENSG00000149311 ENSG00000135423 ENSG00000151012 PMC2661962__F1 Where Do MAIT Cells Fit in the Family of Unconventional T Cells? ENSG00000139193 ENSG00000158473 ENSG00000109906 ENSG00000153029 PMC6003288__F2 Luteolin inhibition of receptor-mediated tumor progression.Notes: Involvement of luteolin (green) in modifying processes necessary for metastasis ENSG00000198793 ENSG00000168036 PMC6003288__F3 Luteolin-mediated extrinsic and intrinsic apoptosis in breast cancer.Notes: Illustration abridging the involvement of luteolin (green) in purposed apoptotic pathways ENSG00000168040 ENSG00000026103 PMC9037381__F3 Pathogenic Mechanisms of Fusobacterium nucleatum on Oral Epithelial Cells ENSG00000162711 ENSG00000115008 ENSG00000160703 ENSG00000281166 ENSG00000168036 ENSG00000189403 ENSG00000117335 ENSG00000100985 PMC8203678__F5 Genome-wide portrait of pervasive drug contaminants ENSG00000091704 ENSG00000081181 ENSG00000118520 ENSG00000158516 PMC7841880__F1 Canonical PTEN pathway depicting PI3K/AKT/mTOR and MAPK/ERK signaling ENSG00000124102 ENSG00000144895 ENSG00000198793 ENSG00000164327 PMC7333890__F2 Stress responses to aneuploidy and radiation ENSG00000149311 ENSG00000175054 PMC3359076__F5 Regulation of thrombin-induced RelA/p65 nuclear translocation by the Rho-actin pathway ENSG00000173039 PMC4077945__F1 Lipid metabolites as metabolic messengers in inter-organ communication ENSG00000170522 ENSG00000026103 PMC4979518__F6A mTORC2 controls cancer cell survival by modulating gluconeogenesis ENSG00000130957 ENSG00000108515 ENSG00000198793 ENSG00000126457 ENSG00000164327 ENSG00000213341 ENSG00000168610 ENSG00000074800 ENSG00000204673 ENSG00000118515 ENSG00000123374 ENSG00000164708 ENSG00000124253 ENSG00000136872 PMC3134408__F1 Proposed molecular pathways in arterial, venous and lymphatic specification in a developing embryo ENSG00000196411 ENSG00000176692 ENSG00000135547 ENSG00000117707 ENSG00000285438 ENSG00000118257 ENSG00000203883 PMC11053014__F1 Model of Hippo sinaling pathway in mammalian cells and the activity of Hippo sinaling pathway controls the dynamic localization of YAP/TAZ between nucleus and cytoplasm ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC11053014__F2 Molecular mechanism by which mechanical cues regulate YAP/TAZ ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC6352980__F2 Paths to stemness: building the ultimate antitumour T cell ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000127528 ENSG00000168036 ENSG00000150457 ENSG00000131023 ENSG00000168610 ENSG00000136826 ENSG00000071564 ENSG00000170365 ENSG00000128342 ENSG00000283060 ENSG00000162892 ENSG00000125968 PMC6988818__F2 The Renin-Angiotensin System and Vitamin D in Keloid Disorder—A Review ENSG00000188404 PMC4580089__F1 Intracellular trypanosomatid parasites evade the protective role of IFNG signaling by targeting essential components of the JAK-STAT pathway ENSG00000111537 ENSG00000115415 ENSG00000125347 PMC5362524__F8 Liver X receptors agonist GW3965 re-sensitizes gefitinib-resistant human non-small cell lung cancer cell to gefitinib treatment by inhibiting NFKB in vitro ENSG00000138798 ENSG00000146648 PMC8324391__F1 Reactive Oxygen Species as a Link between Antioxidant Pathways and Autophagy ENSG00000083290 ENSG00000126775 ENSG00000150907 ENSG00000112561 ENSG00000096717 ENSG00000079999 PMC4951124__F6 CXCL12/CXCR4 Axis Activation Mediates Prostate Myofibroblast Phenoconversion through Non-Canonical EGFR/MEK/ERK Signaling ENSG00000107562 ENSG00000291971 ENSG00000146648 ENSG00000121966 PMC8396202__F2 Cell-Free DNA in Rheumatoid Arthritis ENSG00000150782 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000163568 ENSG00000172936 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC2723817__F1 Targeting lung inflammation: novel therapies for the treatment of COPD ENSG00000108691 ENSG00000163739 ENSG00000196591 ENSG00000124107 ENSG00000121807 PMC11913674__F1 mRNA vaccines immunogenicity ENSG00000183735 ENSG00000088888 ENSG00000134982 ENSG00000186716 ENSG00000172936 ENSG00000107201 ENSG00000135828 ENSG00000276561 ENSG00000164342 PMC5671742__F2 Anticancer drugs that induce oxidative stress on endothelial cells ENSG00000178568 PMC8190181__F2 Signaling pathways in cancer-associated fibroblasts and targeted therapy for cancer ENSG00000137834 ENSG00000087245 ENSG00000107562 ENSG00000088305 ENSG00000120693 ENSG00000156574 ENSG00000129514 ENSG00000168610 ENSG00000121966 ENSG00000170365 ENSG00000163914 ENSG00000180875 ENSG00000100985 ENSG00000078098 PMC8190181__F3 Signaling pathways in cancer-associated fibroblasts and targeted therapy for cancer ENSG00000019991 ENSG00000107562 ENSG00000113140 ENSG00000198793 ENSG00000156574 ENSG00000026508 ENSG00000162692 ENSG00000146648 ENSG00000121966 PMC8190181__F4 Signaling pathways in cancer-associated fibroblasts and targeted therapy for cancer ENSG00000133110 ENSG00000122691 ENSG00000170558 ENSG00000169710 ENSG00000162692 ENSG00000146648 ENSG00000121966 ENSG00000291944 PMC5723914__F1 FGFR signaling pathway PMC12026832__F3 Signaling pathways in cardiac fibroblast ENSG00000125398 ENSG00000118526 ENSG00000134982 ENSG00000132646 ENSG00000198793 ENSG00000197905 ENSG00000168036 ENSG00000150457 ENSG00000164532 ENSG00000131023 PMC8221395__F4 Use of Iron Oxide Nanoparticles to Reprogram Macrophage Responses and the Immunological Tumor Microenvironment ENSG00000178573 ENSG00000087842 PMC4983539__F1 Innate Immune Evasion Strategies of DNA and RNA viruses ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000121060 ENSG00000276561 PMC4986693__F6 Gastrin inhibits a novel, pathological colon cancer signaling pathway involving EGR1, AE2 and P-ERK ENSG00000110148 PMC4261029__F1 Schematic illustration of the mTOR signaling pathway, including major upstream regulators and downstream substrates for both the mTORC2 and mTORC1 kinase complexes ENSG00000169047 ENSG00000198793 ENSG00000145979 ENSG00000164327 ENSG00000167965 PMC11618000__F8 MST2-mediated Hippo signaling pathway involved in T ENSG00000197905 ENSG00000007866 ENSG00000131023 ENSG00000074219 PMC8605871__F7 Whole Exome Sequencing Study in a Family with Type 2 Diabetes Mellitus ENSG00000180210 ENSG00000177169 ENSG00000171105 ENSG00000135218 ENSG00000198793 ENSG00000001626 ENSG00000026103 PMC5957449__F3 Sustained activation of detoxification pathways promotes liver carcinogenesis in response to chronic bile acid-mediated damage ENSG00000185022 ENSG00000116044 ENSG00000140505 ENSG00000103222 ENSG00000127948 ENSG00000168765 ENSG00000106546 PMC4459531__F1 Serrated Pathway to Colorectal Cancer ENSG00000157764 ENSG00000134982 PMC3206070__F2 Temporal Order of Genetic and Pathway Alterations in Tumorigenesis ENSG00000173040 ENSG00000134982 ENSG00000121879 ENSG00000130508 ENSG00000146648 ENSG00000139687 PMC6590809__F1 Apical sodium-dependent bile acid transporter inhibition with volixibat improves metabolic aspects and components of non-alcoholic steatohepatitis in Ldlr-/-.Leiden mice ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC4115279__F1 Death-Defining Immune Responses After Apoptosis ENSG00000120868 ENSG00000168040 ENSG00000084774 PMC2690992__F2 Signaling control of mesenchymal and amoeboid cell phenotypes ENSG00000111859 ENSG00000163914 ENSG00000088538 PMC4013251__F1 Canonical microRNA (miRNA) biogenesis pathway: miRNAs are initially transcribed as long, variable-length hairpin RNA substrates called primary miRNAs (pri-miRNAs) directly off the DNA template in the nucleus by RNA polymerase II (A) ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC7982415__F4 NLR-mediated signaling pathway in mammals ENSG00000278718 ENSG00000162711 ENSG00000150782 ENSG00000163568 ENSG00000137757 ENSG00000196954 ENSG00000163565 ENSG00000106100 PMC4781997__F3 Apoptosis through death receptors: a signaling pathway in TLE(HS) ENSG00000104689 ENSG00000100906 ENSG00000173039 ENSG00000243509 ENSG00000064012 ENSG00000139687 PMC7982415__F2 TLR-mediated signaling pathway ENSG00000162711 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000168040 ENSG00000168404 ENSG00000175104 ENSG00000164305 ENSG00000184216 PMC7499322__F2 Promotional roles of MSC-derived exosomes in tumors ENSG00000178860 PMC7499322__F3 Inhibitory roles of MSC-derived exosomes in tumors ENSG00000178860 ENSG00000166851 PMC4892133__F1 Rapid degradation of HIF-1A by the ubiquitin-proteasome pathway, during normoxia ENSG00000163739 PMC4189449__F1 Pathway where human papillomavirus (HPV)16 E5, E6 and E7 oncoproteins regulate cyclooxygenase-2 (COX-2) expression associated with the cervical carcinogenesis ENSG00000171720 ENSG00000177606 ENSG00000146648 PMC3678733__F3 Visualization of curated components of pathways and inferred interacting proteins and small molecules ENSG00000250506 ENSG00000150457 PMC3678733__F1 Human Hippo signaling pathway ENSG00000004975 ENSG00000126016 PMC7143141__F1 Long-term recreational football training in successful aging ENSG00000105835 ENSG00000198793 ENSG00000145782 PMC8226666__F2 Hippo Pathway: A Master Regulatory Network Important in Cancer ENSG00000198793 ENSG00000165757 PMC11641450__F2 Modulation of WNT/Beta-catenin signaling pathway by natural compounds in cancers ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4741750__F3 Down-regulation of IKKB expression in glioma-infiltrating microglia/macrophages is associated with defective inflammatory/immune gene responses in glioblastoma ENSG00000081041 ENSG00000100906 ENSG00000109320 ENSG00000050748 ENSG00000065559 ENSG00000135341 ENSG00000121879 ENSG00000277943 ENSG00000169245 ENSG00000187554 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000171608 PMC8226666__F1 Hippo Pathway: A Master Regulatory Network Important in Cancer ENSG00000291971 ENSG00000163914 PMC8533696__F3 Targeting Notch to Maximize Chemotherapeutic Benefits: Rationale, Advanced Strategies, and Future Perspectives ENSG00000128917 ENSG00000171791 ENSG00000133961 ENSG00000114315 ENSG00000168610 PMC6046102__F1 TNBC: The current and upcoming therapeutic strategies targeting the mutant proteins or pathways to enable tailored-therapeutics ENSG00000149311 ENSG00000012048 ENSG00000124102 ENSG00000175054 ENSG00000109452 ENSG00000120875 ENSG00000198793 ENSG00000101224 ENSG00000146648 ENSG00000196712 ENSG00000139618 PMC10540835__F1 Dopaminergic regulation of inflammation and immunity in Parkinson's disease: friend or foe? ENSG00000162711 ENSG00000125538 PMC4661875__F2 Intrinsic and extrinsic apoptotic pathways: The intrinsic, or mitochondrial, pathway is initiated from within the cell in response to DNA damage, loss of cell-survival factors and severe cell stress ENSG00000102871 ENSG00000168040 ENSG00000026103 PMC2887084__F1 New Strategies in Head and Neck Cancer: epidermal growth factor receptor inhibition in head and neck cancer ENSG00000163235 ENSG00000291971 ENSG00000113070 ENSG00000138798 ENSG00000198793 PMC3837032__F7 Impaired Nrf2 activation and antioxidant gene expression in fetal endothelial cells in GDM ENSG00000178573 ENSG00000079999 PMC3203325__F2 XPC: Implications in cancer and oxidative DNA damage ENSG00000012061 ENSG00000134574 ENSG00000132646 ENSG00000177084 ENSG00000122008 PMC3552145__F10 PGN-induced miR-132 and miR-212 in TLR signaling ENSG00000174125 ENSG00000170458 ENSG00000187554 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC4896389__F4 Tumour Microenvironment after Radiotherapy: Mechanisms of Resistance and Recurrence ENSG00000169248 ENSG00000169245 ENSG00000019991 ENSG00000107562 ENSG00000161921 ENSG00000138755 ENSG00000112715 ENSG00000121966 ENSG00000065802 PMC3121188__F7 ERK-dependent signalling during conditioning and extinction of fear ENSG00000130522 ENSG00000140044 ENSG00000078098 PMC4351152__F1 MTOR pathway is regulated by numerous upstream pathways, typically in response to growth factors (anabolic) or energy/nutrient deficiency (cell static or catabolic) ENSG00000198793 ENSG00000164327 PMC7003380__F1 Biology of ICOS in the tumour microenvironment ENSG00000134982 ENSG00000163599 ENSG00000049768 PMC7003380__F2 Targeting regulatory and/or effector T cells with ICOS agonistic or antagonistic antibodies ENSG00000134982 PMC2430694__F2 Inflammatory Pain: The Cellular Basis of Heat Hyperalgesia ENSG00000196689 PMC4251421__F2 Simplified diagram of the mammalian target of rapamycin (mTOR) signaling pathway and its relationship with autophagy and apoptosis ENSG00000163914 PMC5727303__F2 Inhibitors of Wnt signalling ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000173273 PMC8134874__F9 Regulation and mechanism of YAP/TAZ in the mechanical microenvironment of stem cells ENSG00000149930 ENSG00000160551 ENSG00000135090 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC6149873__F1 Inverse relationship between canonical and non-canonical Hedgehog signaling in colon cancer stem cell (CSC) differentiation ENSG00000128602 PMC10706788__F13 Pathway of glutathione metabolism by EHP in the late stages of infection ENSG00000002549 PMC10706788__F10 Pathway of purine metabolism by EHP in the early stages of infection ENSG00000142192 ENSG00000148926 ENSG00000105697 ENSG00000171540 PMC10706788__F11 Pathway of glutathione metabolism by EHP in the early stages of infection ENSG00000002549 PMC6776186__F6 Graphical abstract of the model of the activation of IL2RG/JAK/STAT following the overexpression of the ITK-SYK fusion gene ENSG00000147168 ENSG00000113263 PMC8134874__F3 Regulation and mechanism of YAP/TAZ in the mechanical microenvironment of stem cells ENSG00000129219 ENSG00000150457 ENSG00000124181 ENSG00000131023 PMC8155538__F2 Renal Ciliopathies: Sorting Out Therapeutic Approaches for Nephronophthisis ENSG00000143147 ENSG00000167580 ENSG00000106571 ENSG00000160602 ENSG00000164690 ENSG00000001626 ENSG00000128602 PMC5712254__F1 Metabolic Advantages and Vulnerabilities in Brain Metastases ENSG00000067057 ENSG00000153574 ENSG00000115419 ENSG00000159399 PMC6764236__F2 Regulation of neutrophil metabolism ENSG00000198793 ENSG00000026103 PMC6540463__F3 PI3K-AKT signaling pathway which was achieved by DAVID pathway analysis ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 PMC6540463__F4 Hippo signaling pathway which was achieved by DAVID pathway analysis ENSG00000126016 ENSG00000109321 ENSG00000134982 ENSG00000136997 ENSG00000081051 ENSG00000132849 ENSG00000072415 PMC8924093__F3 Anti-HER2 therapy in metastatic breast cancer: many choices and future directions ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000146648 PMC6011341__F3 The Base Excision Repair Pathway ENSG00000105486 ENSG00000132646 ENSG00000177084 PMC4012266__F2 The autophagy process and signaling pathway ENSG00000152348 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC3432194__F2 Epistasis network for WTCCC GWAS of bipolar disorder ENSG00000101782 ENSG00000170775 ENSG00000187535 ENSG00000134326 ENSG00000152977 ENSG00000188404 ENSG00000181610 ENSG00000113749 ENSG00000184465 ENSG00000165323 ENSG00000184985 ENSG00000111707 ENSG00000104497 ENSG00000109674 ENSG00000204020 ENSG00000136011 ENSG00000112276 ENSG00000155886 ENSG00000156049 ENSG00000074621 ENSG00000119900 ENSG00000164796 ENSG00000182768 ENSG00000130226 ENSG00000097096 ENSG00000164176 ENSG00000145348 ENSG00000170959 ENSG00000179104 ENSG00000102934 ENSG00000172296 ENSG00000122965 ENSG00000082397 ENSG00000185305 ENSG00000048740 ENSG00000124782 ENSG00000185052 ENSG00000139372 ENSG00000125255 ENSG00000058729 ENSG00000144057 ENSG00000143013 ENSG00000164484 ENSG00000072803 ENSG00000182533 ENSG00000137055 ENSG00000087274 ENSG00000151151 ENSG00000068878 PMC7875896__F8 Protective mechanism of levo‐tetrahydropalmatine against liver fibrosis ENSG00000087245 PMC6588884__F2 MET protein structure (a) and HGF/MET signaling pathway (b) ENSG00000019991 PMC8209516__F3 Markers and Reporters to Reveal the Hierarchy in Heterogeneous Cancer Stem Cells ENSG00000094631 ENSG00000148400 ENSG00000168036 PMC9526459__F2 Revisiting potential value of antitumor drugs in the treatment of COVID-19 ENSG00000010671 ENSG00000164342 PMC9496095__F2 Post-Translational Modification Networking in WNK-Centric Hypertension Regulation and Electrolyte Homeostasis ENSG00000126562 ENSG00000060237 ENSG00000146021 PMC8745273__F6 Brachygnathia Inferior in Cloned Dogs Is Possibly Correlated with Variants of Wnt Signaling Pathway Initiators ENSG00000027075 ENSG00000072803 ENSG00000101333 PMC4252624__F5 Glutathione peroxidase activity pathway which was significantly altered in the liver of female LMB, obtained from GSEA, featuring GO terms ENSG00000211445 ENSG00000167468 ENSG00000143198 ENSG00000116157 ENSG00000275565 ENSG00000176153 ENSG00000164305 PMC8662121__F1 Type I interferon in the treatment of COVID‐19 ENSG00000183735 ENSG00000088888 ENSG00000130234 ENSG00000172936 ENSG00000136869 ENSG00000276561 ENSG00000164342 PMC4252624__F6 Classical Complement Pathway affected in the ovary of female LMB (by gene set enrichment analysis (GSEA)) ENSG00000039537 ENSG00000113600 ENSG00000288512 ENSG00000166278 ENSG00000182326 ENSG00000157131 ENSG00000236625 PMC8662121__F2 Type I interferon in the treatment of COVID‐19 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC7261019__F1 Rerouting of glucose utilization in RA and SLE T cells ENSG00000172840 PMC7814730__F4 DILI-related processes inferred from predicted targets and pathway annotations ENSG00000170890 ENSG00000151632 ENSG00000140505 ENSG00000070770 ENSG00000085662 ENSG00000148344 ENSG00000147082 ENSG00000124588 ENSG00000111725 ENSG00000127334 PMC6156325__F4 BH4 modulates the nitrosation of key proteins in the Ubiquitin-Proteasome system ENSG00000175166 ENSG00000108671 ENSG00000163636 PMC5524794__F1 Protoporphyrin IX biosynthetic pathway in the shell gland of brown egg laying hens ENSG00000144659 ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000188690 ENSG00000115657 ENSG00000118777 PMC2692422__F7 IL-1Beta-induced upregulation of RGS4 expression in colonic SMCs via canonical IKK2/IKBA/NFKB signaling is differentially modulated by the MAPK and PI3K/Akt/GSK3B pathways ENSG00000125538 ENSG00000117152 PMC5901847__F1 Diagram of signal pathways and molecules participating in the preservation of the pluripotency state and reprogramming ENSG00000132906 ENSG00000002330 ENSG00000134982 ENSG00000138798 ENSG00000168036 ENSG00000128342 ENSG00000128602 ENSG00000281857 PMC3446495__F1 Impaired immune system in patients with systemic lupus erythematosus (SLE) ENSG00000138378 ENSG00000169896 ENSG00000118503 ENSG00000134982 ENSG00000140968 ENSG00000115267 ENSG00000152689 ENSG00000116701 ENSG00000185651 ENSG00000276561 PMC7230071__F1 Key regulators of ferroptosis ENSG00000168003 ENSG00000163930 ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000184207 ENSG00000079999 PMC9573482__F7 Quercetin and Resveratrol Differentially Decrease Expression of the High-Affinity IgE Receptor (FcERI) by Human and Mouse Mast Cells ENSG00000213658 ENSG00000144895 PMC4015830__F2 Intersection of BC modules 143, 79 and 82 ENSG00000065361 ENSG00000027644 ENSG00000250506 ENSG00000142273 ENSG00000145386 ENSG00000124762 ENSG00000171446 ENSG00000145604 ENSG00000100385 ENSG00000103479 ENSG00000102189 ENSG00000178568 ENSG00000108312 ENSG00000016402 PMC7140647__F5 Different potential contributing players and their pathways activated in proposed antibody-dependent NK cell-mediated cytotoxicity in the thyroid gland of AITD patients ENSG00000149269 ENSG00000231179 ENSG00000204520 PMC5657500__F1 Death receptor signaling in the heart: cell survival, apoptosis, and necroptosis ENSG00000132906 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000164305 PMC8998918__F4 Environmental Phenol and Paraben Exposure Risks and Their Potential Influence on the Gene Expression Involved in the Prognosis of Prostate Cancer ENSG00000157554 ENSG00000002330 ENSG00000104368 PMC6707065__F1 Normal Adrenal Steroidogenesis Pathway ENSG00000203859 ENSG00000179142 ENSG00000176387 PMC5878942__F3 Physiology and role of irisin in glucose homeostasis ENSG00000150907 ENSG00000124253 ENSG00000026103 PMC4467417__F5 Circular RNA ITCH has inhibitory effect on ESCC by suppressing the Wnt/Beta-catenin pathway ENSG00000004975 ENSG00000154342 ENSG00000078747 PMC5878942__F2 Physiology and role of irisin in glucose homeostasis ENSG00000068976 ENSG00000124253 ENSG00000159399 PMC2474812__F1 Classical and back-door pathways of androgen biosynthesis ENSG00000086696 ENSG00000151632 ENSG00000197888 ENSG00000196620 ENSG00000187134 PMC3923149__F2 Co-regulation of hepatic wound healing and regenerative responses via TWEAK- and LTBeta-mediated cellular cross-talk ENSG00000108691 ENSG00000111321 PMC8301972__F2 Functional Implications of the Dynamic Regulation of EpCAM during Epithelial-to-Mesenchymal Transition ENSG00000124216 ENSG00000119888 ENSG00000122691 ENSG00000019549 PMC6800286__F7 The pathway leading to IL-1B release from NK92 and its inhibition by DMF or MMF ENSG00000278718 ENSG00000088305 ENSG00000125538 PMC2615236__F1 Regulation of IGF-I Function by Proinflammatory Cytokines: At the Interface of Immunology and Endocrinology ENSG00000124102 ENSG00000117020 ENSG00000002330 ENSG00000198793 ENSG00000168036 ENSG00000140443 PMC6915875__F6 The mechanism of AML cell-secreted exosomal miR-4532 in hematopoiesis of HSCs ENSG00000168610 ENSG00000182195 PMC5803787__F7 Model for the fate decision of XY PGCs regulated by stage-specific FGF9 levels ENSG00000146857 ENSG00000188425 ENSG00000102678 PMC5413166__F5 An example of innate immune response induced by E2 in ML-1 cells ENSG00000185022 ENSG00000161921 ENSG00000179091 ENSG00000151835 ENSG00000102312 ENSG00000138760 PMC4383884__F5 Cisplatin response pathway ENSG00000142494 ENSG00000112499 ENSG00000197208 PMC5250589__F1 Impact of ELS on the normal development of tissues and organs ENSG00000145321 ENSG00000132693 PMC6262822__F1 Parts of the signaling pathways of the five mutated proteins in the 5 syndromes of this review ENSG00000165409 ENSG00000036828 PMC3197531__F12 Beta-Adrenergic Receptor-PI3K Signaling Crosstalk in Mouse Heart: Elucidation of Immediate Downstream Signaling Cascades ENSG00000198793 ENSG00000105723 PMC3641604__F9 The innate immune antiviral response triggered by IFNB and TNFA in AECs ENSG00000183735 ENSG00000088888 ENSG00000140279 ENSG00000185745 ENSG00000107201 ENSG00000131323 ENSG00000140274 ENSG00000175104 PMC4940190__F1 Adipose tissue dysfunction and its effects on tumor metabolism ENSG00000198793 ENSG00000100219 ENSG00000159399 PMC3732559__F5 HMGB1 in Cancer: Good, Bad, or Both? ENSG00000177169 ENSG00000189403 PMC12167820__F2 Transcriptome analysis of S ENSG00000112977 ENSG00000114054 ENSG00000062485 PMC2984446__F10 PI 3 Kinase Related Kinases-Independent Proteolysis of BRCA1 Regulates Rad51 Recruitment during Genotoxic Stress in Human Cells ENSG00000012048 ENSG00000051180 PMC4673337__F1 Innate receptor signaling and stefin B influence NFKB activation and caspase-11 expression in macrophages ENSG00000162711 ENSG00000150782 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC6116003__F2 Pathway for Type I tumor formation ENSG00000117713 ENSG00000157764 PMC2843693__F2 Molecular Origins of Cancer ENSG00000157764 ENSG00000134982 ENSG00000168036 ENSG00000121879 ENSG00000146648 PMC4850162__F2 Riboclustering-mediated signaling pathways that regulate innate inflammatory modulators, including cytokines/chemokines ENSG00000187554 ENSG00000136869 ENSG00000164342 PMC6116003__F6 Wnt Signaling Cascade ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC2811231__F7 Gene program of neutrophil recruitment and tissue injury based on gene expression and in vitro data ENSG00000050628 ENSG00000160013 ENSG00000148344 ENSG00000073756 ENSG00000285456 ENSG00000171051 ENSG00000011422 ENSG00000125538 ENSG00000026508 ENSG00000164400 ENSG00000172936 ENSG00000180549 ENSG00000275565 ENSG00000184216 ENSG00000115594 ENSG00000123610 PMC3819010__F2 EBPR metabolic map inferred from the Accumulibacter clade IIA genome, adapted from ) ENSG00000175054 ENSG00000156110 ENSG00000108960 PMC4472235__F2 Evidence for Immune Response, Axonal Dysfunction and Reduced Endocytosis in the Substantia Nigra in Early Stage Parkinson’s Disease ENSG00000163435 ENSG00000171105 ENSG00000198793 ENSG00000163914 ENSG00000173599 PMC5136518__F1 Alterations in DLPFC layer 3 pyramidal cells in schizophrenia ENSG00000106683 ENSG00000070831 ENSG00000149269 ENSG00000182541 PMC6078908__F6 Conceptual Circuit Model for How External Warming Induces and Links Sleep and Body CoolingSkin warming activates a pathway that runs through the spinal cord and is relayed by glutamatergic neurons in the lateral parabrachial nucleus [, , ] ENSG00000005381 ENSG00000167419 PMC3624298__F1 Downregulation of human NK cell-mediated cytotoxicity pathway genes in response to Gal-9 ENSG00000131015 ENSG00000131019 ENSG00000284213 ENSG00000111981 ENSG00000117091 ENSG00000231179 ENSG00000204520 PMC6822471__F4 Docosahexaenoic acid (DHA) signaling pathway detected by GSEA ENSG00000100290 ENSG00000002330 ENSG00000133056 ENSG00000171791 ENSG00000105723 PMC4393792__F2 T Cell Metabolic Fitness in Anti-Tumor Immunity ENSG00000111537 ENSG00000096717 ENSG00000106546 PMC7311998__F5 Molecular mechanisms of ID1-mediated BMP signaling pathway to control GLP-1 secretion in GLUTag cells ENSG00000170365 ENSG00000120693 ENSG00000204217 ENSG00000125968 PMC5134126__F1 Osteoclasts arise from hematopoietic monocyte/macrophage precursors upon interaction of RANKL with its receptor RANK ENSG00000175104 ENSG00000131196 PMC4177360__F5 TLR signaling and CXCR4/7 in human liver MDB formation ENSG00000172936 ENSG00000136869 ENSG00000121966 ENSG00000164342 PMC8909056__F1 Polyamine Immunometabolism: Central Regulators of Inflammation, Cancer and Autoimmunity ENSG00000129932 PMC7531038__F6 Possible intracellular signaling pathways activated in chondrocytes upon treatment with pararama hair extract ENSG00000108691 ENSG00000161921 ENSG00000100906 ENSG00000026508 ENSG00000065559 ENSG00000136869 ENSG00000185591 ENSG00000112715 PMC7230488__F2 MAPK signaling pathway with nodes color-coded based on the z-value obtained from the meta-analysis of the GSE53987, GSE12649 and GSE21138 datasets ENSG00000105329 ENSG00000135090 ENSG00000102871 ENSG00000130522 ENSG00000115904 ENSG00000169032 ENSG00000149269 ENSG00000136997 ENSG00000006116 ENSG00000196712 ENSG00000109756 ENSG00000026103 ENSG00000087095 ENSG00000157764 ENSG00000108861 ENSG00000109320 ENSG00000065559 ENSG00000213341 ENSG00000130159 ENSG00000127191 ENSG00000006062 ENSG00000081189 ENSG00000117020 ENSG00000128272 ENSG00000170458 ENSG00000143507 ENSG00000184371 ENSG00000175104 PMC5520917__F8 OA-induced growth inhibition of colon cancer via reprogramming fatty acid metabolism under hypoxia ENSG00000134982 ENSG00000169710 ENSG00000168036 PMC2634968__F6 Identification of Potential Pathway Mediation Targets in Toll-like Receptor Signaling ENSG00000129474 ENSG00000145365 ENSG00000184216 PMC3724356__F2 Molecular events in cholangiocarcinogenesis ENSG00000138798 ENSG00000171791 ENSG00000146648 PMC2634968__F7 Identification of Potential Pathway Mediation Targets in Toll-like Receptor Signaling ENSG00000174123 ENSG00000174125 ENSG00000239732 ENSG00000145365 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC8504951__F7 Genetic deletion of endothelial microRNA-15a/16-1 promotes cerebral angiogenesis and neurological recovery in ischemic stroke through Src signaling pathway ENSG00000291971 ENSG00000112715 ENSG00000077782 ENSG00000168610 PMC8062762__F4 Summary diagram showing potential points in endometrial cell signaling pathways which may be influenced by BVDV infection ENSG00000111537 ENSG00000134321 ENSG00000105397 ENSG00000115415 ENSG00000115267 ENSG00000131323 ENSG00000169871 ENSG00000175104 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC3042723__F2 Signaling pathways regulating dendritic spine actin remodeling with the induction of LTP by theta burst stimulation (TBS).Schematic of signaling pathways linking three classes of synaptic to regulation of the actin cytoskeleton ENSG00000070831 ENSG00000291971 PMC3672788__F6 Summary for the effect of calcineurin inhibitor, tacrolimus, on the regulation of RANKL expression through IL-6/sIL-6R/JAK2/STAT3/SOCS3 pathway ENSG00000168610 PMC7976506__F5 Targeting the AnxA1/Fpr2/ALX pathway regulates neutrophil function, promoting thromboinflammation resolution in sickle cell disease ENSG00000122966 ENSG00000171049 PMC3734934__F6 Disruption of mindin exacerbates cardiac hypertrophy and fibrosis PMC6627624__F5 Scheme to summarize the current understanding of triterpenoid biosynthesis in metazoans ENSG00000067064 ENSG00000110921 PMC3263561__F2 Interaction between glia and neurons may lead to neuron damage and death ENSG00000170458 ENSG00000136869 PMC6627624__F7 Scheme of the post squalene pathway for cholesterol biosynthesis ENSG00000090402 ENSG00000144857 ENSG00000128602 PMC6635068__F1 Rb pathway loss and assays for their detection ENSG00000135446 ENSG00000105810 ENSG00000139687 PMC2634968__F2 Identification of Potential Pathway Mediation Targets in Toll-like Receptor Signaling ENSG00000276561 PMC9295467__F2 Generation of Leydig-like cells: approaches, characterization, and challenges ENSG00000073060 ENSG00000138039 PMC8868544__F1 AHR and NRF2 in Skin Homeostasis and Atopic Dermatitis ENSG00000171759 ENSG00000106546 ENSG00000079999 PMC3788325__F2 Signaling pathways in RILF ENSG00000168036 PMC2634968__F5 Identification of Potential Pathway Mediation Targets in Toll-like Receptor Signaling ENSG00000141968 ENSG00000164342 PMC6446225__F1 Proposed overview of the vascular immunopathology of sickle cell disease (SCD) ENSG00000003436 ENSG00000135218 ENSG00000171049 ENSG00000136869 ENSG00000171051 PMC7678118__F5 PDGFRA/EGFR signaling activation and effects on RAS/MAPK pathway ENSG00000163235 ENSG00000291971 ENSG00000138798 ENSG00000115904 PMC11213636__F7 Combination of Pirfenidone and Andrographolide Ameliorates Hepatic Stellate Cell Activation and Liver Fibrosis by Mediating TGFB/Smad Signaling Pathway PMC7772566__F6 Mapping germ-layer specification preventing genes in hPSCs via genome-scale CRISPR screening ENSG00000081181 ENSG00000110921 ENSG00000105835 ENSG00000112972 ENSG00000130414 ENSG00000172893 ENSG00000213741 ENSG00000087008 ENSG00000141744 ENSG00000135069 ENSG00000120437 ENSG00000167508 ENSG00000171720 ENSG00000104549 ENSG00000185591 ENSG00000131473 ENSG00000169021 ENSG00000109743 ENSG00000099194 ENSG00000052802 ENSG00000132170 ENSG00000172809 ENSG00000160752 ENSG00000067064 ENSG00000198189 ENSG00000127184 ENSG00000112303 ENSG00000143450 ENSG00000092020 ENSG00000184076 ENSG00000197142 ENSG00000262814 ENSG00000162365 ENSG00000108344 ENSG00000068878 PMC10565042__F1 Diverse types and molecular mechanisms of the Wnt signaling pathway ENSG00000070831 ENSG00000100592 ENSG00000134982 ENSG00000168036 PMC5538118__F2 Molecular map of pathways that lead ROS to cause OPC dysfunctioning in SZ ENSG00000010810 ENSG00000198793 ENSG00000134853 ENSG00000197461 PMC10565042__F2 Involvement of ncRNAs in modulating the Wnt signaling pathway in prostate cancer ENSG00000134982 ENSG00000168036 PMC10502727__F1 Basic research on chordoma ENSG00000198793 ENSG00000146648 PMC9126727__F4 Investigating the Molecular Mechanism of Quercetin Protecting against Podocyte Injury to Attenuate Diabetic Nephropathy through Network Pharmacology, MicroarrayData Analysis, and Molecular Docking ENSG00000108821 ENSG00000073756 PMC10565042__F3 Wnt signaling pathway-related ncRNAs in the regulation of invasion and migration in prostate cancer ENSG00000163251 ENSG00000134982 ENSG00000026508 ENSG00000168036 ENSG00000150764 ENSG00000029993 ENSG00000253352 ENSG00000104332 ENSG00000165795 ENSG00000140807 ENSG00000039600 PMC10565042__F4 Wnt signaling pathway-related ncRNAs in the regulation of EMT, apoptosis, stemness, and CRPC formation in prostate cancer ENSG00000138795 ENSG00000134982 ENSG00000026508 ENSG00000168036 ENSG00000103769 ENSG00000104332 PMC7789127__F1 Dual-specificity tyrosine-regulated kinase 1B expression and activity ENSG00000117000 ENSG00000198793 ENSG00000163914 ENSG00000105204 PMC7655968__F2 Simplified representation of the structured reaction pathway of glycolysis (Maria, ), and of the TRP synthesis (in the yellow area) (Maria et al., ) in E ENSG00000122966 ENSG00000172005 ENSG00000150787 PMC4428446__F2 Scheme of the signal transduction pathways that control C ENSG00000196511 ENSG00000070831 ENSG00000170367 PMC9274486__F8 miR-199a-3p/5p regulate tumorgenesis via targeting Rheb in non-small cell lung cancer ENSG00000185386 ENSG00000198793 ENSG00000146648 PMC8091816__F4 Sulforaphane suppresses lipopolysaccharide‐ and Pam3CysSerLys4‐mediated inflammation in chronic obstructive pulmonary disease via toll‐like receptors ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC8174708__F1 Targeting Amino Acid Metabolic Vulnerabilities in Myeloid Malignancies ENSG00000124275 ENSG00000146733 ENSG00000116761 PMC5596436__F7 Selected microRNA-target (cell cycle pathways) interaction data ENSG00000145604 ENSG00000094804 ENSG00000108055 ENSG00000142230 ENSG00000132646 ENSG00000123374 ENSG00000277273 ENSG00000276876 PMC7519685__F4 Understanding lipotoxicity in NAFLD pathogenesis: is CD36 a key driver? ENSG00000171791 ENSG00000026103 PMC1933372__F3 RAN regulation pathway constituents exhibiting abundance changes, with a figure adapted from the GeneGo MetaCore database ENSG00000099901 ENSG00000153201 ENSG00000171540 ENSG00000116030 ENSG00000132341 PMC8789115__F5 Graphlet adjacency captures centrality of cancer driver genes in the FSAHF pathway ENSG00000100084 ENSG00000189060 ENSG00000118900 ENSG00000139687 ENSG00000183495 ENSG00000099991 PMC7795059__F1 Scheme illustrating the diverse autophagic pathways in cancer cells ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000083290 ENSG00000144848 ENSG00000145782 PMC9578877__F12 Ageing-Associated Transcriptomic Alterations in Peri-Implantitis Pathology: A Bioinformatic Study ENSG00000019991 ENSG00000105550 ENSG00000102871 ENSG00000138798 ENSG00000198793 ENSG00000049768 ENSG00000135341 ENSG00000112715 ENSG00000132965 ENSG00000077150 ENSG00000179348 ENSG00000026103 ENSG00000118972 ENSG00000104365 ENSG00000171105 ENSG00000142192 ENSG00000109321 ENSG00000078399 ENSG00000173039 ENSG00000113088 ENSG00000143252 ENSG00000177606 ENSG00000134853 ENSG00000067955 ENSG00000127948 ENSG00000150630 PMC11762533__F4 Effect of aberrant activation of the HGF/c-MET signaling pathway on PD-L1 expression in various tumors: increased PD-L1 expression in NSCLC by activating the downstream pathway PI3K-AKT-mTOR ENSG00000019991 ENSG00000091317 ENSG00000138378 ENSG00000115415 ENSG00000198793 ENSG00000183742 PMC7970325__F8 Reconstructed differential DNA repair molecular network for the comparison of Papillary cancer (PC) vs Follicular cancer (FC) ENSG00000213928 ENSG00000142453 ENSG00000108654 ENSG00000124762 ENSG00000183765 ENSG00000080546 ENSG00000105486 ENSG00000177595 ENSG00000132781 ENSG00000144554 ENSG00000104320 ENSG00000162607 ENSG00000105810 ENSG00000276787 ENSG00000166169 ENSG00000109674 ENSG00000292286 ENSG00000085117 ENSG00000109321 ENSG00000181544 ENSG00000187790 ENSG00000115392 ENSG00000187741 ENSG00000112039 ENSG00000107175 ENSG00000127334 ENSG00000139618 ENSG00000132646 ENSG00000112378 ENSG00000075218 ENSG00000172977 ENSG00000096717 ENSG00000146648 ENSG00000198586 ENSG00000204397 ENSG00000275679 ENSG00000083093 ENSG00000284238 ENSG00000172613 ENSG00000070831 ENSG00000077152 ENSG00000129355 ENSG00000196470 ENSG00000206075 ENSG00000175054 ENSG00000123415 ENSG00000139372 ENSG00000129071 ENSG00000189403 ENSG00000123374 ENSG00000185591 ENSG00000051180 ENSG00000177519 ENSG00000177084 ENSG00000115107 ENSG00000188486 ENSG00000136492 ENSG00000005339 ENSG00000175793 ENSG00000064393 ENSG00000132478 ENSG00000127191 ENSG00000149311 ENSG00000172667 ENSG00000128272 ENSG00000135446 ENSG00000161513 ENSG00000175643 ENSG00000197299 ENSG00000140398 ENSG00000178966 ENSG00000114315 ENSG00000288325 ENSG00000113360 ENSG00000122512 PMC11762533__F2 Impact of HGF/c-MET Signaling Pathway on Immune-Suppressive Cells and Their Interactions: Immune-suppressive cells primarily include CAFs, TAMs, MDSCs, and Tregs ENSG00000178860 ENSG00000105672 ENSG00000019991 ENSG00000133048 ENSG00000160867 ENSG00000175832 ENSG00000118520 ENSG00000168610 PMC7185194__F6 Novel universal mechanism of immunosuppressive A151 ODN ENSG00000140992 ENSG00000136997 ENSG00000164327 ENSG00000168610 PMC11762533__F3 Targeting HGF/c-MET signaling to regulate the tumor microenvironment: Implications for counteracting tumor immune evasion ENSG00000019991 ENSG00000118520 ENSG00000168610 PMC6943888__F1 Regulation of D-secretase in neurodegenerative diseases ENSG00000142192 ENSG00000115415 ENSG00000135250 PMC11762533__F1 Targeting HGF/c-MET signaling to regulate the tumor microenvironment: Implications for counteracting tumor immune evasion ENSG00000019991 ENSG00000168036 ENSG00000168610 PMC7185194__F2 GGIN identified by IPA software ENSG00000005339 ENSG00000177606 ENSG00000168610 PMC11274073__F11 Therapeutic Potential of Dalbergia pinnata (Lour.) Prain Essential Oil in Alzheimer’s Disease: EEG Signal Analysis In Vivo, SH-SY5Y Cell Model In Vitro, and Network Pharmacology ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000168610 PMC9646457__F7 Myeloid checkpoints for cancer immunotherapy ENSG00000291971 ENSG00000104972 ENSG00000273686 ENSG00000118520 ENSG00000186818 ENSG00000274513 PMC2801257__F1 Signaling through the Lymphocyte receptor induces a novel regulatory motif for MAP kinase activation ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000010671 PMC9110840__F1 Advances in the Study of the Ubiquitin-Editing Enzyme A20 ENSG00000102871 ENSG00000147789 ENSG00000125538 ENSG00000082512 ENSG00000172936 ENSG00000175104 ENSG00000127191 PMC5421515__F1 Shear Stress in Autophagy and Its Possible Mechanisms in the Process of Atherosclerosis ENSG00000162711 ENSG00000105329 ENSG00000125538 ENSG00000198793 ENSG00000127528 ENSG00000162692 PMC6279936__F1 Processes of liver fibrosis progression and regression during human hepatosplenic schistosomiasis ENSG00000138798 ENSG00000189403 ENSG00000113520 PMC5421515__F2 Shear Stress in Autophagy and Its Possible Mechanisms in the Process of Atherosclerosis ENSG00000177169 ENSG00000123395 ENSG00000198793 ENSG00000284099 ENSG00000196689 PMC5421515__F3 Shear Stress in Autophagy and Its Possible Mechanisms in the Process of Atherosclerosis ENSG00000177169 ENSG00000170365 ENSG00000198793 ENSG00000078237 PMC6626370__F2 Convergent inflammatory signaling through NFKB potentiates BRD4-dependent transcription of VI mediators, a result suppressed by apabetalone ENSG00000141867 ENSG00000102871 ENSG00000189403 ENSG00000121807 PMC6651063__F6 DE mRNA corresponding genes in the cultivar “Huoche” under heat stress ENSG00000163435 ENSG00000203783 ENSG00000131188 PMC4429650__F3 Signaling pathway for zinc prevention of atherosclerosis in monocytes/macrophages and vascular endothelial cells: a proposed hypothesis ENSG00000162692 ENSG00000132693 PMC7185565__F2A Emerging Themes in PDZ Domain Signaling ENSG00000100151 ENSG00000147044 ENSG00000169071 ENSG00000162337 ENSG00000100592 ENSG00000156299 ENSG00000163914 ENSG00000168036 ENSG00000132849 ENSG00000292254 PMC5739098__F8 Proposed model of changes in epigenetic status before and after establishing hiONs from hiPSCs and epigenetic silencing by hyperglycemia in orexin neurons ENSG00000159921 ENSG00000147162 ENSG00000198408 ENSG00000145321 ENSG00000096717 PMC5145083__F9 Neuropathy optic glaucomatosa induced by systemic hypertension through activation endothelin-1 signaling pathway in central retinal artery in rats ENSG00000130234 PMC7807718__F6 Scheme summarizing the inhibition of H2O2-induced oxidant injury by FPNP via the up-regulation of antioxidant enzymes and TGFB/Smad pathway PMC9481960__F1 Knowledge-guided deep learning models of drug toxicity improve interpretation ENSG00000291971 ENSG00000198846 ENSG00000146648 PMC6635557__F3 Schematic model of AngII-induced and mechanical stress-induced signaling pathway in vascular smooth muscle caveolae ENSG00000182533 ENSG00000146648 PMC12182306__F12 Scheme highlighting the main findings of the study ENSG00000105550 ENSG00000106546 PMC2574839__F2 Androgen synthesis pathway and therapeutic targets ENSG00000277893 ENSG00000203859 ENSG00000203857 PMC3726398__F2 Reconstructing the interactions among different modules of the MAPK pathway ENSG00000169291 ENSG00000138798 PMC4104784__F5 RNA-seq upregulation of energy metabolism gene expression ENSG00000178127 ENSG00000143252 ENSG00000074800 ENSG00000140740 ENSG00000100412 ENSG00000196839 ENSG00000010256 ENSG00000131828 ENSG00000062485 PMC5144662__F6 T-cell receptor (TCR) signaling pathway ENSG00000104365 ENSG00000291603 ENSG00000198851 ENSG00000163599 ENSG00000006062 ENSG00000110395 ENSG00000077150 ENSG00000213658 ENSG00000135446 ENSG00000010810 ENSG00000177606 ENSG00000113520 ENSG00000164400 ENSG00000113525 ENSG00000131196 ENSG00000130669 ENSG00000086730 PMC3492937__F5 Stem cell pathways analysis for label-retaining cancer cell (LRCC) ENSG00000107404 ENSG00000138795 ENSG00000107562 ENSG00000109101 ENSG00000171794 ENSG00000168487 ENSG00000168036 ENSG00000101266 ENSG00000118971 ENSG00000135144 ENSG00000136826 ENSG00000125084 ENSG00000091073 ENSG00000170365 ENSG00000178403 ENSG00000138115 ENSG00000164736 ENSG00000196549 ENSG00000077782 ENSG00000139687 PMC8392691__F2 Renin–Angiotensin System in the Tumor Microenvironment of Glioblastoma ENSG00000175054 ENSG00000130234 ENSG00000198793 ENSG00000168036 ENSG00000168646 PMC8657427__F2 Tumor Microenvironment Features and Chemoresistance in Pancreatic Ductal Adenocarcinoma: Insights into Targeting Physicochemical Barriers and Metabolism as Therapeutic Approaches ENSG00000002330 ENSG00000026508 ENSG00000168610 PMC7338450__F2 GA12/13 signaling in metabolic diseases ENSG00000124422 ENSG00000096717 PMC12093937__F4 Drug targeting on skin cancer stem cell niche ENSG00000291971 ENSG00000134982 ENSG00000198793 ENSG00000135903 ENSG00000168036 ENSG00000164690 ENSG00000128602 ENSG00000168610 PMC4385444__F1 Disease implications of the Hippo/YAP pathway ENSG00000126016 ENSG00000186575 ENSG00000144560 ENSG00000163914 ENSG00000197905 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC7338450__F4 GA12/13 signaling in metabolic diseases ENSG00000170961 ENSG00000205221 ENSG00000126775 ENSG00000148400 ENSG00000145782 PMC8580835__F2 Host cell-intrinsic innate immune recognition of SARS-CoV-2 ENSG00000183735 ENSG00000088888 ENSG00000101146 ENSG00000187608 ENSG00000115415 ENSG00000114030 ENSG00000110713 PMC8560708__F3 Targeting DNA Damage Response Pathway in Ovarian Clear Cell Carcinoma ENSG00000117713 ENSG00000149311 ENSG00000175054 ENSG00000131747 ENSG00000087586 ENSG00000051180 ENSG00000166851 PMC8560708__F1 Targeting DNA Damage Response Pathway in Ovarian Clear Cell Carcinoma ENSG00000149311 ENSG00000175054 ENSG00000132646 ENSG00000051180 PMC10669528__F4 Process of GSDMD in the pathogenesis of systemic onfection ENSG00000278718 ENSG00000170458 ENSG00000130234 ENSG00000163568 PMC4826038__F3 Serpinin/pGlu-serpinin formation, its signaling pathway and PN-1-dependent biogenesis of secretory granules in (neuro)endocrine cells ENSG00000185591 PMC11956425__F5 CXCR3/PLC/IP3/IP3R signaling pathway stimulated by PT ENSG00000186810 ENSG00000111537 ENSG00000001626 PMC4243952__F2 Impact of cellobiose on central carbon metabolism, amino acid biosynthesis and thiamine biosynthesis of Saccharomyces cerevisiae ENSG00000081181 ENSG00000074800 ENSG00000090863 ENSG00000100412 ENSG00000179091 ENSG00000167513 ENSG00000139515 ENSG00000118520 ENSG00000124253 ENSG00000146701 PMC8392407__F1 Unraveling the IGF System Interactome in Sarcomas Exploits Novel Therapeutic Options ENSG00000196411 ENSG00000142627 ENSG00000140443 PMC8392407__F2 Unraveling the IGF System Interactome in Sarcomas Exploits Novel Therapeutic Options ENSG00000150457 ENSG00000131023 ENSG00000140443 PMC12093937__F1 Niche for normal and cancer skin stem cells ENSG00000071564 ENSG00000026103 PMC12093937__F2 Core signaling pathways in skin stem cell niche ENSG00000291971 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000164690 ENSG00000150457 ENSG00000168610 ENSG00000131023 PMC7236211__F1 Pathway engineering strategy for succinate production in S ENSG00000122966 ENSG00000117118 ENSG00000172005 PMC7443482__F3 Biosynthesis, transport, and roles of the coenzyme thiamine diphosphate in the model plant Arabidopsis ENSG00000107130 PMC12093937__F3 Signaling network in skin cancer stem cell niche ENSG00000071564 ENSG00000122691 ENSG00000291971 ENSG00000134982 ENSG00000198793 ENSG00000135903 ENSG00000168036 ENSG00000164690 ENSG00000150457 ENSG00000128602 ENSG00000168610 ENSG00000131023 PMC6586801__F2 Hypoxia signaling in human diseases and therapeutic targets ENSG00000196839 ENSG00000170425 PMC3193400__F2 Activation of NFKB and regulation of downstream transcriptional antioxidant and pro-oxidant targets ENSG00000104856 ENSG00000130649 ENSG00000173039 ENSG00000087250 PMC9240796__AF1 Pharmacological inhibition of sphingolipid synthesis reduces ferroptosis by stimulating the HIF-1 pathway PMC4742390__F2 BMI1 regulates BCSC ENSG00000168283 ENSG00000125084 PMC4350683__F6 Regulation of sonic hedgehog expression by integrin B1 and epidermal growth factor receptor in intestinal epithelium ENSG00000128602 ENSG00000146648 PMC3668831__F1 Iron regulation by hepcidin ENSG00000170365 ENSG00000010704 ENSG00000168610 PMC8657427__F7 Tumor Microenvironment Features and Chemoresistance in Pancreatic Ductal Adenocarcinoma: Insights into Targeting Physicochemical Barriers and Metabolism as Therapeutic Approaches ENSG00000135218 ENSG00000169710 ENSG00000115419 ENSG00000062485 PMC6410669__F2 Scorpion and spider venoms in cancer treatment: state of the art, challenges, and perspectives ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 ENSG00000026103 PMC9437626__F2 Therapeutic targets by traditional Chinese medicine for ischemia-reperfusion injury induced apoptosis on cardiovascular and cerebrovascular diseases ENSG00000102871 ENSG00000166278 PMC7463953__F2 Putative target gene interaction network graph generated using Ingenuity Pathway Analysis of miR-34 and miR-181 family miRNAs nodes within a simulated cell ENSG00000196839 ENSG00000168081 PMC7565866__F3 Micronutrients in one-carbon (1C) metabolism and DNA methylation PMC7275785__F1 Hyperprogression to a dual immune blockade followed by subsequent response with cabozantinib in metastatic poor-risk clear cell renal cell carcinoma with NOTCH mutation ENSG00000198793 ENSG00000114315 PMC5746039__F6 Glycolysis and its branching pathways ENSG00000159399 ENSG00000026103 PMC3831618__F2 Fe(II)-dependent, uridine-5′-monophosphate Alpha-ketoglutarate dioxygenases in the synthesis of 5′-modified nucleosides ENSG00000204020 ENSG00000204021 PMC11144369__F1 Outlines of the AhR signaling pathway ENSG00000110711 ENSG00000181019 ENSG00000291971 ENSG00000140505 ENSG00000106546 PMC8006404__F7 Proposed mechanism about excessive caffeine intake-disturbed differentiation of myogenic progenitors through retinoic acid (RA) signaling pathway ENSG00000009709 ENSG00000111049 ENSG00000078814 PMC11144369__F2 FICZ-induced, AhR-mediated skin carcinogenesis from UV radiation ENSG00000110711 ENSG00000140465 ENSG00000146648 ENSG00000106546 PMC8790316__F3 Central Role of Extracellular Vesicles in the Mechanisms of Thrombosis in COVID-19 Patients With Cancer and Therapeutic Strategies ENSG00000115008 ENSG00000110799 ENSG00000134982 ENSG00000173599 PMC3751776__F2 BTK signaling pathway ENSG00000095585 ENSG00000168610 PMC3745216__F3 TGFB signalling pathway ENSG00000166167 ENSG00000100387 ENSG00000113558 ENSG00000079999 PMC10740823__F9 Graphical abstract of the mechanism PMC6233116__F7 Tbx5 is required for a mesoderm–endoderm bidirectional signaling loop for cardiopulmonary development ENSG00000134245 ENSG00000164690 ENSG00000089225 PMC6897284__F3 Epigenetic regulation of miR-126 by metabolic changes in malignant mesothelioma ENSG00000143799 ENSG00000131473 ENSG00000169047 ENSG00000096717 PMC9407090__F1 Prefrontal Cortex Response to Prenatal Insult and Postnatal Opioid Exposure ENSG00000099866 ENSG00000188404 ENSG00000007908 ENSG00000115232 ENSG00000110876 PMC9407090__F2 Prefrontal Cortex Response to Prenatal Insult and Postnatal Opioid Exposure ENSG00000047410 ENSG00000123104 ENSG00000088256 ENSG00000169032 ENSG00000182621 ENSG00000120251 ENSG00000137841 PMC5949883__F2 Network of metabolic pathways that regulate leukemia ENSG00000136997 PMC2758708__F2 Diagrammatic representation of non-canonical Wnt signalling in a mammalian cell ENSG00000004975 ENSG00000164932 ENSG00000107404 ENSG00000198742 ENSG00000120057 ENSG00000173218 ENSG00000075275 ENSG00000112655 ENSG00000161202 ENSG00000104332 PMC7564482__F1 Folate-homocysteine metabolism pathway and possible causes of folate deficiency ENSG00000228716 ENSG00000124275 ENSG00000116984 PMC7862610__F6 Association of dementia with immunoglobulin G N-glycans in a Chinese Han Population ENSG00000132693 ENSG00000062485 PMC7589139__F5 The proposed molecular mechanism of glucose-6-phosphate dehydrogenase (G6PD) deficiency in human aortic endothelium and monocytes ENSG00000162692 PMC3179812__F6 Stem Cell Marker (Nanog) and Stat-3 Signaling Promote MicroRNA-21 Expression and Chemoresistance in Hyaluronan/CD44-activated Head and Neck Squamous Cell Carcinoma Cells ENSG00000026508 ENSG00000168610 PMC11964643__F2 Effector-mediated inflammation ENSG00000070831 ENSG00000149269 ENSG00000091106 ENSG00000169871 ENSG00000175104 ENSG00000168610 ENSG00000141569 PMC6386537__F3 Immunologic Pathways in Protective versus Maladaptive Host Responses ENSG00000172680 ENSG00000138798 ENSG00000139269 ENSG00000163083 ENSG00000111321 ENSG00000121807 ENSG00000142224 ENSG00000150782 ENSG00000131142 ENSG00000135960 ENSG00000122756 ENSG00000117400 ENSG00000128052 ENSG00000136997 ENSG00000163734 ENSG00000147896 ENSG00000157625 ENSG00000128342 ENSG00000162892 ENSG00000292332 ENSG00000026103 ENSG00000087095 ENSG00000104899 ENSG00000143185 ENSG00000081041 ENSG00000112964 ENSG00000099985 ENSG00000242689 ENSG00000179091 ENSG00000145777 ENSG00000130159 ENSG00000127191 ENSG00000162594 ENSG00000186810 ENSG00000226275 ENSG00000108691 ENSG00000168066 ENSG00000170458 ENSG00000137077 ENSG00000177606 ENSG00000126353 ENSG00000175104 ENSG00000127948 PMC8306345__F6 Anti-Inflammatory Influences of Cystic Fibrosis Transmembrane Conductance Regulator Drugs on Lung Inflammation in Cystic Fibrosis ENSG00000278718 ENSG00000162711 ENSG00000108691 ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC3815439__F13 MicroRNAs: molecular features and role in cancer ENSG00000168040 ENSG00000096717 PMC2679989__F1 Function of Nod-like Receptors in Microbial Recognition and Host Defense ENSG00000167207 ENSG00000187796 ENSG00000177606 ENSG00000157625 ENSG00000166278 PMC8758217__F1 Mini review ATF4 and GRP78 as novel molecular targets in ER-Stress modulation for critical COVID-19 patients ENSG00000128272 ENSG00000144895 ENSG00000100387 ENSG00000162772 ENSG00000079999 PMC2408406__F1 Microvasculature in the pathogenesis of inflammatory bowel disease ENSG00000187554 ENSG00000173599 ENSG00000136869 PMC8671602__F4 DExD/H-box helicases: multifunctional regulators in antiviral innate immunity ENSG00000168872 ENSG00000162711 ENSG00000088888 ENSG00000125538 ENSG00000109606 ENSG00000174885 ENSG00000215301 PMC7790571__F3 KEGG pathway: map04064 ENSG00000095585 ENSG00000104856 ENSG00000149311 ENSG00000226275 ENSG00000213658 ENSG00000135960 ENSG00000102871 ENSG00000186716 ENSG00000083799 ENSG00000150455 ENSG00000121060 ENSG00000135517 PMC8671602__F2 DExD/H-box helicases: multifunctional regulators in antiviral innate immunity ENSG00000144028 ENSG00000088888 ENSG00000067248 ENSG00000136271 ENSG00000109606 ENSG00000145833 ENSG00000181381 ENSG00000108654 ENSG00000131323 ENSG00000175104 ENSG00000089737 PMC11782130__F7 Location and role of Gtl2-Dio3 target genes in the Wnt and PI3K-Akt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000130702 ENSG00000169047 ENSG00000168036 ENSG00000184349 ENSG00000198892 ENSG00000104332 ENSG00000064300 ENSG00000145623 ENSG00000155011 ENSG00000166501 ENSG00000142627 ENSG00000112964 ENSG00000189056 ENSG00000197565 ENSG00000106483 ENSG00000169242 ENSG00000091879 ENSG00000106829 ENSG00000066468 ENSG00000118785 ENSG00000186716 ENSG00000188803 ENSG00000134853 ENSG00000140285 ENSG00000154188 ENSG00000168646 ENSG00000146648 PMC8671602__F3 DExD/H-box helicases: multifunctional regulators in antiviral innate immunity ENSG00000213928 ENSG00000164430 ENSG00000105397 ENSG00000163565 ENSG00000181381 ENSG00000174953 ENSG00000132153 ENSG00000142166 PMC5997150__F2 Requirement of the Arf6-based mesenchymal pathway in both mesenchymal-type and amoeboid-type cancer invasion ENSG00000019991 ENSG00000115109 ENSG00000138798 ENSG00000198670 ENSG00000165527 PMC8671602__F1 DExD/H-box helicases: multifunctional regulators in antiviral innate immunity ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000174953 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000089737 ENSG00000276561 ENSG00000164342 PMC8546001__F4 BMP signaling requirements in mucociliary cell types ENSG00000170365 PMC8978634__F6 Herpes Simplex Virus 1 Induces Microglia Gasdermin D-Dependent Pyroptosis Through Activating the NLR Family Pyrin Domain Containing 3 Inflammasome ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC3013041__F5 Relationship between transcription factors and their regulatory factors ENSG00000102034 ENSG00000130522 PMC9130463__F3 Transient Receptor Potential Vanilloid1 (TRPV1) Channel Opens Sesame of T Cell Responses and T Cell-Mediated Inflammatory Diseases ENSG00000107485 ENSG00000196689 PMC5860983__F11 Human binge alcohol intake inhibits TLR4-MyD88 and TLR4-TRIF responses but not TLR3-TRIF pathway: HspA1A and PP1 play selective regulatory roles ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC11808218__F11 Asiaticoside Attenuates Chronic Restraint Stress-Induced Hippocampal CA1 Neuronal Ferroptosis via Activating BDNF/Nrf2/GPX4 Signaling Pathway ENSG00000151012 ENSG00000167468 ENSG00000072274 PMC12229020__F1 ECM deposition-induced inflammation and fibrosis ENSG00000162711 ENSG00000177606 ENSG00000096717 PMC6010831__F9 Proposed model of the mechanism that links mitochondrial dysfunction and insulin resistance in non‐alcoholic steatohepatitis ENSG00000171105 ENSG00000042832 ENSG00000116688 ENSG00000106459 PMC7347220__F5 Lyme disease bacterium, Borrelia burgdorferi, stimulates an inflammatory response in human choroid plexus epithelial cells ENSG00000173821 ENSG00000187608 ENSG00000089127 ENSG00000187634 ENSG00000157601 ENSG00000265972 ENSG00000241644 ENSG00000168961 ENSG00000178685 ENSG00000065717 ENSG00000134321 ENSG00000134326 ENSG00000163734 ENSG00000132109 ENSG00000185633 ENSG00000185745 ENSG00000107742 ENSG00000221869 ENSG00000162654 ENSG00000276561 ENSG00000147119 ENSG00000136960 ENSG00000158887 ENSG00000111331 ENSG00000121060 ENSG00000115461 ENSG00000124875 ENSG00000110057 ENSG00000109272 ENSG00000104213 ENSG00000163815 ENSG00000064300 ENSG00000164488 ENSG00000178342 ENSG00000198732 ENSG00000241878 ENSG00000135899 ENSG00000188290 ENSG00000068079 ENSG00000277571 ENSG00000168062 ENSG00000118004 ENSG00000003137 ENSG00000174348 ENSG00000163840 ENSG00000188176 ENSG00000103723 ENSG00000130775 ENSG00000166106 ENSG00000110446 ENSG00000141753 ENSG00000175287 ENSG00000181374 ENSG00000152049 ENSG00000270885 ENSG00000063180 ENSG00000139832 ENSG00000186377 ENSG00000105088 ENSG00000130208 ENSG00000168209 ENSG00000081041 ENSG00000130589 ENSG00000107736 ENSG00000131652 ENSG00000172183 ENSG00000184979 ENSG00000108691 ENSG00000182175 ENSG00000078053 ENSG00000160867 ENSG00000137965 ENSG00000135114 ENSG00000291555 ENSG00000126353 ENSG00000028137 ENSG00000123689 ENSG00000006016 PMC8436873__F1 Impaired macrophages and failure of steroidogenesis and spermatogenesis in rat testes with cytokines deficiency induced by diacerein ENSG00000177575 ENSG00000162711 PMC8382889__F1 Stem Cell-Derived Exosomes Potential Therapeutic Roles in Cardiovascular Diseases ENSG00000272398 ENSG00000110651 ENSG00000010278 ENSG00000164176 ENSG00000135404 ENSG00000146648 PMC7408589__F12 Influence of X-rays (7 Gy) on regulation of the p53 pathway (according to the Mus musculus p53 signaling pathway available at https://www.genome.jp/kegg/) in mESCs in presence of LIF (+LIF) and absence of LIF (-LIF) ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000198793 ENSG00000112378 ENSG00000196470 ENSG00000128342 ENSG00000164305 PMC11037034__F3 Novel milestones for early esophageal carcinoma: From bench to bed ENSG00000172936 ENSG00000136869 PMC12229020__F2 Impaired ECM degradation in PCOS ENSG00000128272 ENSG00000145321 ENSG00000171791 ENSG00000106546 PMC12229020__F3 Altered mechanical forces in ECM remodeling ENSG00000145321 PMC5791855__F1 Tuning the depth of quiescence for cancer therapy ENSG00000135446 ENSG00000136997 ENSG00000123374 ENSG00000105810 ENSG00000139687 PMC7322352__F4 MAPK Signaling PathwayGenes in the pathway are colored based on their expression in TN tumors ENSG00000087095 ENSG00000170458 ENSG00000102871 ENSG00000130159 ENSG00000127191 ENSG00000196712 ENSG00000026103 PMC2214701__F3 Building bone to reverse osteoporosis and repair fractures ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000104332 PMC7322352__F5 MAPK Endogenous RNA NetworkThis figure shows the network of interacting protein-coding mRNAs and non-coding microRNAs in the MAPK singling pathway ENSG00000019991 ENSG00000172680 ENSG00000280962 ENSG00000002330 ENSG00000157764 ENSG00000105329 ENSG00000291971 ENSG00000168610 ENSG00000089159 ENSG00000115415 ENSG00000136997 ENSG00000134853 ENSG00000154188 ENSG00000131196 ENSG00000123268 ENSG00000184216 ENSG00000196712 PMC4596691__F4 Transcriptome Analysis of CD4+ T Cells in Coeliac Disease Reveals Imprint of BACH2 and IFNG Regulation ENSG00000121989 ENSG00000157404 ENSG00000090534 ENSG00000163083 ENSG00000111321 ENSG00000187266 ENSG00000100385 ENSG00000122025 ENSG00000117400 ENSG00000163734 ENSG00000173578 ENSG00000162892 ENSG00000107779 ENSG00000139193 ENSG00000182578 ENSG00000112964 ENSG00000119535 ENSG00000147168 ENSG00000184451 ENSG00000163736 ENSG00000145777 ENSG00000166090 ENSG00000186810 ENSG00000084092 ENSG00000146648 ENSG00000115009 ENSG00000113494 ENSG00000110944 ENSG00000019991 ENSG00000171855 ENSG00000102962 ENSG00000105329 ENSG00000138798 ENSG00000163739 ENSG00000183625 ENSG00000112715 ENSG00000121966 ENSG00000064300 ENSG00000150281 ENSG00000049130 ENSG00000135960 ENSG00000122756 ENSG00000175189 ENSG00000128052 ENSG00000292357 ENSG00000037280 ENSG00000026103 ENSG00000081041 ENSG00000242689 ENSG00000054967 ENSG00000175505 ENSG00000126353 ENSG00000204217 PMC9515549__F1 Enabling factor for cancer hallmark acquisition: Small nucleolar RNA host gene 17 ENSG00000168036 ENSG00000105810 ENSG00000168610 PMC9553755__F6 Exploring Potential Biomarkers, Ferroptosis Mechanisms, and Therapeutic Targets Associated with Cutaneous Squamous Cell Carcinoma via Integrated Transcriptomic Analysis ENSG00000087586 PMC9700862__F8 Overall mechanisms involved in CNNM4 overexpression caused by APAP overdose ENSG00000128272 ENSG00000100219 ENSG00000158158 PMC5355168__F1 Warburg effect, hexokinase-II, and radioresistance of laryngeal carcinoma ENSG00000109452 ENSG00000168610 PMC5467070__F1 Lipopolysaccharide induces apoptosis of hepatocytes via the TLR4/PI3K/Akt/GSK-3B pathway ENSG00000170458 ENSG00000136869 PMC7410168__F5 Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control ENSG00000236637 ENSG00000213928 ENSG00000101160 ENSG00000187608 ENSG00000089127 ENSG00000157601 ENSG00000163565 ENSG00000020633 ENSG00000185745 ENSG00000185885 ENSG00000103522 ENSG00000168610 ENSG00000137959 ENSG00000184979 ENSG00000183735 ENSG00000138378 ENSG00000111537 ENSG00000164430 ENSG00000088888 ENSG00000188313 ENSG00000163840 ENSG00000105397 PMC2721285__F1 RAS/MAP kinase signaling pathway ENSG00000157404 ENSG00000157764 PMC8894702__F2 miR-1269a and miR-1269b: Emerging Carcinogenic Genes of the miR-1269 Family ENSG00000198774 ENSG00000132906 ENSG00000168438 ENSG00000128710 ENSG00000124766 ENSG00000197386 ENSG00000164305 PMC8618211__F2 Clinical Manifestations, Pathogenesis, Diagnosis and Treatment of Peripheral Neuropathies in Connective Tissue Diseases: More Diverse and Frequent in Different Subtypes than Expected ENSG00000079432 ENSG00000166278 ENSG00000105205 ENSG00000236625 PMC6964037__F4 Functional network analysis of I-MDSCs in CRC microenvironment ENSG00000087095 ENSG00000156076 ENSG00000134982 ENSG00000167941 ENSG00000113558 ENSG00000148175 ENSG00000185269 ENSG00000168610 PMC9308790__F8 Molecular mechanisms underlying TRIM25-regulated DOX-induced cardiotoxicity ENSG00000100219 ENSG00000121060 PMC6290882__F1 Hedgehog signaling pathway ENSG00000128602 PMC5865869__F3 Differentially-expressed gene pathway network generated using CluePedia ENSG00000163914 ENSG00000172936 ENSG00000164342 PMC6162445__F3 Mechanism of GPCR bias agonism involves insulin receptor activation ENSG00000175054 ENSG00000169047 ENSG00000100985 ENSG00000135577 PMC2435603__F8 Potentiation of Nerve Growth Factor-Induced Neurite Outgrowth by Fluvoxamine: Role of Sigma-1 Receptors, IP3 Receptors and Cellular Signaling Pathways ENSG00000070831 PMC3265821__F1 Change in RAF isoform usage in response to a RAS mutation ENSG00000157764 PMC6121429__F3 Insulin signaling ENSG00000169047 PMC2441985__F3 The regulation of the insulin signaling pathway by miRNA cluster mmu–mir-183–96–182 ENSG00000169047 ENSG00000160691 PMC9686289__F8 Exploring the pathogenesis linking traumatic brain injury and epilepsy via bioinformatic analyses ENSG00000071655 ENSG00000281614 ENSG00000283934 ENSG00000160058 ENSG00000115415 ENSG00000119471 ENSG00000077585 ENSG00000135414 ENSG00000163754 ENSG00000136040 ENSG00000134698 PMC12176804__F5 IL-17 signaling pathway was enriched in the BD vs ENSG00000197747 ENSG00000108691 ENSG00000143546 ENSG00000149968 ENSG00000163220 ENSG00000108688 ENSG00000100985 ENSG00000143556 ENSG00000115009 PMC7758031__F1 Regulatory mechanisms of DELLA stability by PTMs ENSG00000100387 ENSG00000113558 ENSG00000167986 PMC5876660__F3 KSHV regulation of the TLR signaling pathway ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC9449932__F2 Multiomics approach reveals the ubiquitination-specific processes hijacked by SARS-CoV-2 ENSG00000213928 ENSG00000187608 ENSG00000169562 ENSG00000183486 ENSG00000157601 ENSG00000276561 ENSG00000105289 ENSG00000088888 ENSG00000105397 ENSG00000121481 ENSG00000177606 ENSG00000172936 ENSG00000168310 ENSG00000175104 ENSG00000277401 PMC7790228__F11 TRK-Fused Gene (TFG), a protein involved in protein secretion pathways, is an essential component of the antiviral innate immune response ENSG00000183735 ENSG00000136457 ENSG00000088888 ENSG00000198793 ENSG00000131323 PMC11984404__F9 Schematic diagram regarding key parts of this study ENSG00000148346 ENSG00000168329 ENSG00000105639 ENSG00000168610 PMC7843579__F8 Schematic diagram illustrating the global view of transcriptional changes in MPTP/p-induced progressive PD mice model ENSG00000148926 ENSG00000198793 ENSG00000163064 ENSG00000166278 ENSG00000149295 PMC5474932__F1 Integrated Transcriptomic and Metabolomic Analysis of Five Panax ginseng Cultivars Reveals the Dynamics of Ginsenoside Biosynthesis ENSG00000110921 ENSG00000197429 ENSG00000151151 PMC9267017__F1 Novel Drugs with High Efficacy against Tumor Angiogenesis ENSG00000070831 ENSG00000010810 ENSG00000163914 ENSG00000168036 PMC11016256__F1 Advances in the Study of Non-Coding RNA in the Signaling Pathway of Pulmonary Fibrosis ENSG00000126778 PMC5440471__F3 Manipulation strategies of neutrophils and the immune system by P ENSG00000125538 PMC5808955__F1 Schematic overview of the effects of Saccharomyces boulardii CNCM I-745 on enzymes within the small intestine ENSG00000090402 ENSG00000174197 ENSG00000150787 PMC9403334__F3 Obstacles for T-lymphocytes in the tumour microenvironment: Therapeutic challenges, advances and opportunities beyond immune checkpoint ENSG00000156026 ENSG00000138741 PMC3618249__F2 Single drug simulation result on T2D model ENSG00000171105 ENSG00000110395 ENSG00000169047 ENSG00000115904 ENSG00000115290 ENSG00000132170 ENSG00000160691 ENSG00000179295 PMC5270220__F1 APP cleavage pathways ENSG00000142192 ENSG00000182240 ENSG00000168615 ENSG00000137845 PMC11016256__F2 Advances in the Study of Non-Coding RNA in the Signaling Pathway of Pulmonary Fibrosis ENSG00000005882 ENSG00000091409 PMC11016256__F3 Advances in the Study of Non-Coding RNA in the Signaling Pathway of Pulmonary Fibrosis ENSG00000104856 ENSG00000173039 ENSG00000189403 PMC3618249__F3 combination drug simulation result on T2D model ENSG00000171105 ENSG00000167941 ENSG00000115290 ENSG00000132170 ENSG00000179295 PMC11016256__F4 Advances in the Study of Non-Coding RNA in the Signaling Pathway of Pulmonary Fibrosis ENSG00000091409 ENSG00000189403 ENSG00000128602 PMC5116470__F1 Some of the known pathways linking DDR to autophagy ENSG00000149311 ENSG00000177169 ENSG00000198793 ENSG00000155792 PMC3058407__F1 Antiviral apoptotic pathway is mediated by IRF-3 and Bax ENSG00000183735 ENSG00000167207 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000164342 PMC3612776__F1 Pathways affected in monogenic hypertensive disease ENSG00000060237 ENSG00000080166 ENSG00000146021 ENSG00000165238 PMC8136436__F1 Biogenesis and clearance of H2S and reactive sulfur species ENSG00000137767 PMC4832112__F1 Necroptotic pathway ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000164342 PMC8745152__F9 Fibroblast Growth Factor 23 Stimulates Cardiac Fibroblast Activity through Phospholipase C-Mediated Calcium Signaling ENSG00000118972 ENSG00000293604 ENSG00000077782 PMC9563553__F1 Impact of the Hippo Pathway and Cell Metabolism on Pathological Complete Response in Locally Advanced Her2+ Breast Cancer: The TRISKELE Multicenter Prospective Study ENSG00000113161 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC5903986__F1 Astrocyte glycogen and lactate: new insights into learning and memory mechanisms ENSG00000291971 ENSG00000198793 PMC6003946__F12 SLIT2-ROBO1/ROBO2 and the CDC42-RAFs-ERK1/2 MAPK cascade ENSG00000164404 ENSG00000145147 ENSG00000149269 ENSG00000196935 ENSG00000185008 PMC8914507__F2 Contributions of glycolytic intermediates and glutamine to collagen protein synthesis ENSG00000092621 ENSG00000135069 ENSG00000146733 ENSG00000115419 PMC6769855__F1 Simple depiction of signaling pathways for the activation of classical NLRP3 inflammasome (canonical and non-canonical) and alternative inflammasome ENSG00000162711 ENSG00000137275 ENSG00000125538 ENSG00000136869 ENSG00000168040 ENSG00000064012 PMC3417373__F4 Signaling cascades that regulate the intrinsic and extrinsic pathways of apoptosis ENSG00000066468 ENSG00000002330 ENSG00000122877 ENSG00000168040 PMC3058986__F8 Possible role of RACK1 in VEGF/Flt1-induced cell migration ENSG00000112715 PMC8638980__F5 Association of air pollution and homocysteine with global DNA methylation: A population-based study from North India ENSG00000125538 PMC9084887__F2 Advances in the Structural and Physiological Functions of SHARPIN ENSG00000172936 ENSG00000127191 PMC6461947__F6 Current understanding of SHON and ERA signalling ENSG00000185591 PMC5555159__F24 Structure, Chemical Synthesis, and Biosynthesis of Prodiginine Natural Products ENSG00000143315 ENSG00000108474 ENSG00000135845 ENSG00000100564 ENSG00000197563 PMC3734592__F5 Ingenuity analysis of representative accumulated proteins in response to inactivation of CRL/SCF system ENSG00000112576 ENSG00000185022 ENSG00000116044 ENSG00000151365 ENSG00000169710 ENSG00000168610 ENSG00000124762 ENSG00000197063 ENSG00000101945 ENSG00000135446 ENSG00000271303 ENSG00000139687 ENSG00000169375 PMC9162151__F3 Pathogenesis and treatment of multiple myeloma ENSG00000002330 ENSG00000198793 PMC10041518__F1 Biosynthetic pathways for pyrimidine and purine nucleotides, relevant inhibitors and oncogenic regulators ENSG00000228716 ENSG00000149311 ENSG00000175054 ENSG00000106348 ENSG00000178035 ENSG00000196839 ENSG00000291814 ENSG00000158825 ENSG00000143179 ENSG00000102967 ENSG00000129187 ENSG00000084774 PMC7915224__F6A Ins and Outs of RAS Effector Complexes ENSG00000165891 ENSG00000198793 ENSG00000132478 ENSG00000205250 ENSG00000168040 ENSG00000149311 ENSG00000175054 ENSG00000112242 ENSG00000135446 ENSG00000163914 ENSG00000136997 ENSG00000082805 ENSG00000133740 ENSG00000123374 ENSG00000105810 ENSG00000282899 ENSG00000026103 PMC10041518__F4 Supraphysiological GTP abundance promotes metastasis through the activation of RHO-family GTPases ENSG00000106348 ENSG00000178035 ENSG00000070831 ENSG00000137198 ENSG00000163914 PMC10041518__F5 Hyperactive nucleotide synthesis confers resistance to a range of therapeutic interventions ENSG00000167468 ENSG00000102967 ENSG00000084774 PMC10041518__F2 Nucleotides fuel cancer cell growth and proliferation ENSG00000228716 ENSG00000065833 ENSG00000147162 ENSG00000136997 ENSG00000158825 ENSG00000102967 PMC10041518__F3 Altered nucleoside handling facilitates cancer cell immune evasion ENSG00000106348 ENSG00000178035 ENSG00000291814 ENSG00000137198 PMC4818674__F1 Calpain-1 and calpain-2: the yin and yang of synaptic plasticity and neurodegeneration ENSG00000198793 PMC7223478__F4 Several major mechanisms that have been implicated in vascular aging ENSG00000163914 ENSG00000145321 ENSG00000010319 PMC6195654__F11 BMP signaling pathway overlapped with the results of the comparison BAVc vs ENSG00000170365 ENSG00000137834 ENSG00000152495 ENSG00000115297 ENSG00000183072 ENSG00000183691 ENSG00000177606 ENSG00000152785 ENSG00000134363 ENSG00000183682 ENSG00000164093 PMC2754156__F3 LPS signal transduction via the MyD88-dependent pathway ENSG00000170458 ENSG00000172936 ENSG00000150455 ENSG00000175104 PMC2754156__F4 LPS signal transduction via the MyD88-independent pathway ENSG00000170458 ENSG00000175104 PMC6195654__F10 Hepatic fibrosis/hepatic stellate cell activation canonical pathway ENSG00000019991 ENSG00000087245 ENSG00000111537 ENSG00000137077 ENSG00000138798 ENSG00000138755 ENSG00000184371 ENSG00000113520 ENSG00000110324 ENSG00000108821 ENSG00000146648 PMC7563523__F1 Proteins, non-coding RNAs, and signaling pathway regulators involved in the lack of response of colorectal adenocarcinoma to pharmacological treatment ENSG00000012061 ENSG00000172831 ENSG00000169554 ENSG00000002330 ENSG00000134982 ENSG00000173638 ENSG00000140505 ENSG00000123191 ENSG00000168036 ENSG00000168040 ENSG00000112715 ENSG00000124216 ENSG00000122691 ENSG00000026508 ENSG00000146648 PMC4762141__F5 Different gene expressions in regulation of actin cytoskeleton pathway in AuNR-treated MDA-MB-231 cells ENSG00000147202 ENSG00000172380 ENSG00000157764 ENSG00000175866 ENSG00000134982 ENSG00000138443 ENSG00000158195 ENSG00000089159 ENSG00000182541 ENSG00000180210 ENSG00000120063 ENSG00000015285 ENSG00000130669 ENSG00000133818 PMC7797663__F1 Central pathway of cancer cachexia involving GDF15 and GFRAL with RET proto-oncogene as a coreceptor ENSG00000187871 ENSG00000130513 PMC6089887__F3 Metabolic pathway map in the plasma comparing common bottlenose dolphins (n = 3, blue columns) and beagle dogs (n = 3, red columns) ENSG00000112977 ENSG00000261857 ENSG00000171540 ENSG00000102977 PMC6136406__F8 Nucleosides isolated from Ophiocordyceps sinensis inhibit cigarette smoke extract-induced inflammation via the SIRT1–nuclear factorKB/p65 pathway in RAW264.7 macrophages and in COPD mice ENSG00000125538 ENSG00000096717 PMC4762141__F4 Differential gene expression in glycolysis/gluconeogenesis pathway in AuNR-treated MDA-MB-231 cells PMC7839966__F5 Comprehensive analysis of the lncRNA-associated competing triplets PMC4779258__F6 Ozone-induced lung inflammation and role of IL-6 signaling pathway: ozone-associated lung inflammation is primarily driven by lipid ozonation products (LOP) and generation of free radicals primarily in lung epithelial cells ENSG00000168610 PMC12207060__F3 Schematic representation illustrates the molecular mechanism regulating MTNR1A, NEAT1 and AANAT gene expression in renal TECs ENSG00000168412 ENSG00000132326 ENSG00000171824 PMC6832198__F4 Intracellular molecular alterations and their effects on tumour microenvironment immune activity ENSG00000157404 ENSG00000198793 PMC8396295__F7 Gene-Metabolite Network Analysis Revealed Tissue-Specific Accumulation of Therapeutic Metabolites in Mallotus japonicus ENSG00000084774 PMC12207060__F1 Diagrammatic representation of the melatonin synthesis pathway and melatonin receptor-mediated cell signaling ENSG00000134640 ENSG00000168412 PMC8361364__F1 Interconnections Between Somatic and Ovarian Aging in Murine Models ENSG00000157404 ENSG00000198793 PMC8550885__F2 Therapeutic mTOR blockade in systemic autoimmunity: Implications for antiviral immunity and extension of lifespan ENSG00000164327 PMC5716761__F7 DEK promoted EMT and angiogenesis through regulating PI3K/AKT/mTOR pathway in triple-negative breast cancer ENSG00000198793 ENSG00000124795 PMC8123408__F2 Cytoguardin: A Tryptophan Metabolite against Cancer Growth and Metastasis ENSG00000129167 ENSG00000170558 PMC8550885__F3 Therapeutic mTOR blockade in systemic autoimmunity: Implications for antiviral immunity and extension of lifespan ENSG00000239732 ENSG00000134982 ENSG00000198793 ENSG00000136869 PMC7442594__F7 Schematic proposed model of HDAC10 in KRAS-driven lung cancer development ENSG00000125398 ENSG00000026508 ENSG00000100429 PMC5415769__F3 RICTOR is upstream of multiple canonical pathways ENSG00000267855 ENSG00000039537 ENSG00000159720 ENSG00000112695 ENSG00000140740 ENSG00000073578 ENSG00000126267 ENSG00000164327 ENSG00000010256 ENSG00000119013 ENSG00000114573 ENSG00000110719 PMC5415769__F2 Canonical pathways form groups for each individual protein ENSG00000112561 ENSG00000164327 ENSG00000138071 ENSG00000158869 ENSG00000127884 ENSG00000111229 ENSG00000143815 ENSG00000291814 ENSG00000163914 ENSG00000005893 ENSG00000136997 ENSG00000197943 ENSG00000083720 ENSG00000128928 ENSG00000117305 ENSG00000142192 ENSG00000197102 ENSG00000100345 ENSG00000117360 ENSG00000010256 ENSG00000023909 ENSG00000132170 ENSG00000267855 ENSG00000224320 ENSG00000137992 ENSG00000166794 ENSG00000144028 ENSG00000097033 ENSG00000070831 ENSG00000140740 ENSG00000105329 ENSG00000073578 ENSG00000196504 ENSG00000198793 ENSG00000159720 ENSG00000171105 ENSG00000112695 ENSG00000081237 ENSG00000138029 ENSG00000126267 ENSG00000162704 ENSG00000273686 ENSG00000105953 ENSG00000114573 ENSG00000092199 ENSG00000274442 ENSG00000168610 ENSG00000135624 ENSG00000110719 ENSG00000166428 ENSG00000281614 ENSG00000111537 ENSG00000167996 ENSG00000137076 ENSG00000092841 ENSG00000119013 PMC2650010__F1 Akt-dependent and independent mechanisms of mTOR regulation in cancer ENSG00000124102 ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC2650010__F2 Akt-dependent and independent mechanisms of mTOR regulation in cancer ENSG00000011566 ENSG00000198793 ENSG00000167965 PMC2650010__F3 Akt-dependent and independent mechanisms of mTOR regulation in cancer ENSG00000198793 ENSG00000167965 PMC4680051__F2 Metabolic networks placing mitochondria at the center of anabolic and bioenergetics pathways in cancer cells ENSG00000092621 PMC5629070__F6 Schematic representation of the proposed IR signal diversification by ligand-induced crosstalk with molecular partners ENSG00000115457 ENSG00000167779 ENSG00000198793 PMC6115946__F8 miRNA regulatory pathway in the control of the protein synthesis through SIRT1—TSC:mTOR ENSG00000198793 ENSG00000096717 ENSG00000140443 PMC4503878__F6 Schematic representation of the dual role of 25-HC in the sterol biosynthesis pathway and the IFN--regulated innate immune response using SBGN system (inset shows key) ENSG00000138135 ENSG00000113161 ENSG00000162772 PMC9266903__F1 Ferroptosis Modulation: Potential Therapeutic Target for Glioblastoma Treatment ENSG00000167468 PMC3738954__F4 Key signaling pathways modulated by WNV infection ENSG00000213928 ENSG00000167207 ENSG00000187608 ENSG00000089127 ENSG00000102871 ENSG00000291971 ENSG00000157601 ENSG00000091592 ENSG00000069956 ENSG00000087077 ENSG00000164305 ENSG00000183735 ENSG00000088888 ENSG00000125538 ENSG00000064012 ENSG00000132906 ENSG00000168040 ENSG00000125347 ENSG00000127191 ENSG00000276561 ENSG00000115415 ENSG00000108700 ENSG00000172936 ENSG00000131323 ENSG00000175104 PMC8740226__F15 Effect of Chinese Herbal Medicine Mixture 919 Syrup on Regulation of the Ghrelin Pathway and Intestinal Microbiota in Rats With Non-alcoholic Fatty Liver Disease ENSG00000115138 ENSG00000121853 PMC3932252__F2 Autophagy is negatively regulated by the phosphatidylinositol 3-kinase (PI3 K)/Akt signaling pathway, which activates mammalian target of rapamycin (mTOR) in response to growth factors and also phosphorylates Beclin 1 ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000198382 ENSG00000023287 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC2822937__F7 Downstream effectors of the ErbB receptor signalling pathway ENSG00000065361 ENSG00000146648 ENSG00000178568 PMC4306938__F9 Schematic presentation for araguspongine C-induced autophagic death in breast cancer cells ENSG00000019991 ENSG00000138798 ENSG00000198793 PMC8896306__F4 Circadian rhythms and cancers: the intrinsic links and therapeutic potentials ENSG00000150457 ENSG00000131023 PMC2754915__F1 Schematic illustration of different pathways of glucose metabolism in cancer cells ENSG00000169710 PMC12103767__F6 Proposed hippocampal signaling pathway altered by early amyloidosis ENSG00000221823 ENSG00000159200 ENSG00000005339 ENSG00000105699 ENSG00000171532 ENSG00000010818 ENSG00000110931 ENSG00000139200 ENSG00000173406 ENSG00000137142 PMC9130080__F45 Triclosan-induced neuroinflammation develops caspase-independent and TNFA signaling pathway associated necroptosis in Neuro-2a cells ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000064012 ENSG00000285379 PMC3829196__F2 The p53-mediated apoptotic signaling pathways ENSG00000149311 ENSG00000175054 ENSG00000112378 ENSG00000120868 ENSG00000026103 PMC3565214__F1 Major oncogenic signaling pathway alterations in urothelial carcinoma ENSG00000198793 PMC6031328__F2 Regulatory mechanisms for alternative splicing impact numerous components of the CME ENSG00000065609 ENSG00000063245 ENSG00000072134 ENSG00000130340 ENSG00000175416 ENSG00000130475 ENSG00000116675 ENSG00000122705 ENSG00000133961 ENSG00000141367 ENSG00000157107 PMC6086351__F1 Small Cell Neuroendocrine Tumors: Cell State Trumps the Oncogenic Driver ENSG00000146648 ENSG00000139687 PMC4593342__F1 Stem cell-derived exosomes: roles in stromal remodeling, tumor progression, and cancer immunotherapy ENSG00000178860 ENSG00000182742 ENSG00000168036 PMC9001149__F10 Signaling pathway and molecular mechanisms underlying TLR/zVAD-induced autophagic cell necroptosis ENSG00000183735 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC2754915__F3 Signalling events which determine glucose utilization within the cell ENSG00000169047 ENSG00000078237 ENSG00000284194 PMC3532876__F2 Vicious spirals of repeating self-accelerating oxidative stress and dysregulated redox and information signaling as possible causes of type 2 diabetes ENSG00000139515 ENSG00000086991 ENSG00000265972 ENSG00000182759 ENSG00000105227 PMC6800950__F4 SREBP pathway mediated NLRP3 inflammasome activation ENSG00000162711 PMC3618452__F3 Metabolomic Analysis Reveals Metabolic Disturbance in the Cortex and Hippocampus of Subchronic MK-801 Treated Rats ENSG00000110721 ENSG00000111837 ENSG00000101958 ENSG00000197386 ENSG00000000971 PMC4160369__F2 Molecular Approaches to Thyroid Cancer Diagnosis ENSG00000157764 ENSG00000198793 ENSG00000165409 PMC6943935__F3 Noncanonical IL-17 signaling ENSG00000141527 ENSG00000144749 ENSG00000115904 ENSG00000175104 ENSG00000146648 ENSG00000115009 ENSG00000076604 PMC3583298__F7 Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation ENSG00000149311 PMC5663620__F1 Novel strategies to prevent the development of multidrug resistance (MDR) in cancer ENSG00000026103 PMC10244677__F1 Integrated high-throughput analysis identifies super enhancers in metastatic castration-resistant prostate cancer ENSG00000141867 ENSG00000013810 ENSG00000186716 ENSG00000134369 PMC9158441__F7 Aconiti Lateralis Radix Praeparata as Potential Anticancer Herb: Bioactive Compounds and Molecular Mechanisms ENSG00000198793 ENSG00000159399 PMC4658032__F8 MFHAS1 Is Associated with Sepsis and Stimulates TLR2/NFKB Signaling Pathway Following Negative Regulation ENSG00000170458 ENSG00000147324 ENSG00000172936 PMC5786286__F5 5-HT2Asignaling pathways ENSG00000291971 ENSG00000171791 PMC6530392__F1 Sublytic C5b-9 promotes tumor growth and survival by activating several signaling pathways ENSG00000002330 ENSG00000069482 ENSG00000150907 ENSG00000168610 PMC11804041__F11 SNHG involved in a serious of cellular biological role in EC ENSG00000148400 ENSG00000198793 ENSG00000124766 PMC6533455__F1 Bone development and skeletal homeostasis ENSG00000281324 ENSG00000162337 ENSG00000134569 ENSG00000167941 ENSG00000106483 PMC3910515__F7 TGFB signaling at the BBB during acute peripheral inflammatory pain ENSG00000170365 ENSG00000105329 PMC8215365__F12 Ligilactobacillus salivarius Strains Isolated From the Porcine Gut Modulate Innate Immune Responses in Epithelial Cells and Improve Protection Against Intestinal Viral-Bacterial Superinfection ENSG00000170458 ENSG00000123572 ENSG00000111837 ENSG00000177606 ENSG00000172005 ENSG00000136869 ENSG00000164342 PMC6697957__F5 Wnt signaling: a promising target for osteoarthritis therapy ENSG00000170365 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000155011 ENSG00000168036 PMC9322890__F5 Recent Advances Regarding the Molecular Mechanisms of Triterpenic Acids: A Review (Part I) ENSG00000132906 ENSG00000291971 ENSG00000198793 ENSG00000120868 ENSG00000164305 PMC7786386__F4 p38-signaling in white adipose tissue browning ENSG00000109819 ENSG00000145321 PMC9322890__F6 Recent Advances Regarding the Molecular Mechanisms of Triterpenic Acids: A Review (Part I) ENSG00000132906 ENSG00000137275 ENSG00000102871 ENSG00000198793 ENSG00000172936 ENSG00000096717 ENSG00000175104 ENSG00000127191 ENSG00000168610 ENSG00000164305 ENSG00000184216 ENSG00000079999 PMC6697957__F3 Wnt signaling: a promising target for osteoarthritis therapy ENSG00000197043 ENSG00000170365 ENSG00000281324 ENSG00000125398 ENSG00000162337 ENSG00000168036 ENSG00000114315 ENSG00000128602 PMC6697957__F1 Wnt signaling: a promising target for osteoarthritis therapy ENSG00000139219 ENSG00000125398 ENSG00000162337 ENSG00000149968 ENSG00000134982 ENSG00000167941 ENSG00000157766 ENSG00000168036 ENSG00000110693 PMC8161352__F5 Endophytes: the novel sources for plant terpenoid biosynthesis ENSG00000180210 ENSG00000197429 ENSG00000139687 PMC7600458__F8 Signaling pathways underlying the cooperative relationship between stearic acid and TNFA for MIP-1A/CCL3 production ENSG00000102871 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 ENSG00000136936 PMC3598692__F8 Toll-like receptor signaling pathway figure supplied by KEGG ] ENSG00000170458 ENSG00000164066 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000143387 PMC3787652__F2 Differentiation and commitment of IL-17-producing T helper (TH)17 cells in the midpoint of other coacting cells in favor of and against the harboring individual ENSG00000162594 ENSG00000138378 ENSG00000115415 ENSG00000137265 ENSG00000107485 ENSG00000049768 ENSG00000177663 ENSG00000168610 ENSG00000112486 ENSG00000106546 ENSG00000069667 PMC11022604__F1 Wnt/Beta-Catenin signaling pathway in hepatocellular carcinoma: pathogenic role and therapeutic target ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9232692__F2 Emerging roles of spliceosome in cancer and immunity ENSG00000168066 ENSG00000063244 PMC5569703__F1 Rapid Evolution of Primate Type 2 Immune Response Factors Linked to Asthma Susceptibility ENSG00000134982 ENSG00000197971 ENSG00000102245 ENSG00000158869 ENSG00000121053 PMC9322890__F7 Recent Advances Regarding the Molecular Mechanisms of Triterpenic Acids: A Review (Part I) ENSG00000132906 ENSG00000164305 ENSG00000079999 PMC3243812__F8 Beta2-adrenergic receptor engagement on a B cell that will make IgE uses a unique signaling pathway to increase the level of IgE produced ENSG00000137845 PMC6253933__F5 Roles of SIRT7 in cancer ENSG00000187531 ENSG00000160445 PMC7501977__F1 Underlying mechanism of mitophagy in influencing COPD with different phenotypes ENSG00000162711 ENSG00000123240 ENSG00000088888 ENSG00000163827 ENSG00000158828 ENSG00000168404 PMC10879685__F2 NSCLC: from tumorigenesis, immune checkpoint misuse to current and future targeted therapy ENSG00000070831 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000125347 ENSG00000168610 ENSG00000141968 ENSG00000115415 ENSG00000136997 ENSG00000107485 ENSG00000124181 ENSG00000077782 ENSG00000146648 PMC9331826__F1 Epithelial–Mesenchymal Transition-Mediated Tumor Therapeutic Resistance ENSG00000120875 ENSG00000168036 PMC9331826__F3 Epithelial–Mesenchymal Transition-Mediated Tumor Therapeutic Resistance ENSG00000133083 ENSG00000167601 ENSG00000168036 ENSG00000146648 PMC11125956__F7 T helper 1 Activation Pathway ENSG00000065675 ENSG00000165030 ENSG00000197272 ENSG00000168961 ENSG00000168610 ENSG00000141968 ENSG00000142166 ENSG00000135077 ENSG00000150782 ENSG00000186810 ENSG00000138378 ENSG00000111537 ENSG00000115415 ENSG00000160223 ENSG00000134545 ENSG00000107485 ENSG00000288185 ENSG00000073861 PMC11125956__F8 T helper 2 Activation Pathway ENSG00000179934 ENSG00000065675 ENSG00000105329 ENSG00000137033 ENSG00000204671 ENSG00000183625 ENSG00000020633 ENSG00000145777 ENSG00000166278 ENSG00000141968 ENSG00000121966 ENSG00000186827 ENSG00000138378 ENSG00000183134 ENSG00000178573 ENSG00000177606 ENSG00000113520 ENSG00000170989 ENSG00000073861 ENSG00000162892 ENSG00000111642 PMC7764163__F2 Simplified canonical NFKB signaling pathway with its many deubiquitinating regulators and the molecular targets of those enzymes ENSG00000104856 ENSG00000137275 ENSG00000102871 ENSG00000157625 ENSG00000083799 ENSG00000127191 PMC5601171__F1 Hedgehog-GLI pathway in embryonic development and cancer: implications for pulmonary oncology therapy ENSG00000106571 ENSG00000134982 ENSG00000164690 ENSG00000128602 ENSG00000118777 ENSG00000111962 PMC3239343__F2 Intracellular signalling during inflammation-induced osteoclastogenesis ENSG00000170909 ENSG00000102871 ENSG00000082512 ENSG00000172936 ENSG00000175104 ENSG00000127191 ENSG00000131196 ENSG00000115594 ENSG00000135605 ENSG00000010671 PMC5696218__F10 Verrucarin J inhibits ovarian cancer and targets cancer stem cells ENSG00000148400 ENSG00000125084 PMC4921457__F1 Mechanisms responsible for aldosterone synthesis in zona glomerulosa cells under normal physiological conditions and excess production in primary aldosteronism ENSG00000196531 ENSG00000067842 ENSG00000140691 ENSG00000185231 ENSG00000179142 ENSG00000168036 PMC4446054__F3 Top enriched network associated with BCa progression ENSG00000142192 ENSG00000110330 ENSG00000109332 ENSG00000110492 ENSG00000164171 ENSG00000112715 ENSG00000108840 ENSG00000159200 ENSG00000117525 ENSG00000121351 ENSG00000162545 ENSG00000083799 ENSG00000139687 ENSG00000115461 PMC5601171__F5 Hedgehog-GLI pathway in embryonic development and cancer: implications for pulmonary oncology therapy ENSG00000138798 ENSG00000198793 ENSG00000136997 ENSG00000128602 ENSG00000146648 PMC5601171__F3 Hedgehog-GLI pathway in embryonic development and cancer: implications for pulmonary oncology therapy ENSG00000106571 ENSG00000198793 ENSG00000164690 ENSG00000128602 ENSG00000118777 PMC2952492__F1 Regulation of neo-vascularization by SDF-1 ENSG00000112715 ENSG00000121966 PMC2774072__F7 Proposed consequences of impaired insulin signaling in AD brain and in the STZ-injected rat brain ENSG00000147162 ENSG00000198408 ENSG00000198793 PMC8774031__F7 Ribosome Biogenesis Serves as a Therapeutic Target for Treating Endometriosis and the Associated Complications ENSG00000172809 ENSG00000101751 ENSG00000198793 ENSG00000166169 ENSG00000177600 PMC8526300__F2 New Horizons for the Roles and Association of APE1/Ref-1 and ABCA1 in Atherosclerosis ENSG00000144366 ENSG00000145794 PMC86511__F9 Common and distinct activities of TGFB and BMP in C2C12 cells ENSG00000170365 PMC9479087__F2 Polyamine metabolism in remodeling immune responses and blocking therapy within the tumor immune microenvironment ENSG00000168003 ENSG00000088826 ENSG00000148832 ENSG00000116649 ENSG00000102172 PMC6067831__F1 The HPA axis ENSG00000120088 PMC7990797__F6 KEGG enrichment pathways of DEGs related to IL-17 signal pathway and cytokine–cytokine receptor interaction ENSG00000110944 ENSG00000150782 ENSG00000115008 ENSG00000108342 ENSG00000126353 ENSG00000177663 ENSG00000115009 ENSG00000076604 PMC7859776__F7 An illustrative model to show the proposed mechanism of miR-126-3p promoting sorafenib resistance in HCC ENSG00000166068 PMC11839412__F1 The relationship between CD133, AKT, and MAPK signaling in cell cycle regulation (By Figdraw ENSG00000198793 ENSG00000163734 ENSG00000146648 PMC11839412__F2 Roles of WNT and Notch in CD133+cell cycle regulation (By Figdraw ENSG00000092439 ENSG00000134982 ENSG00000136997 ENSG00000114315 PMC12021630__F2 Molecular mechanism of PGRN in osteoarthritis ENSG00000105664 ENSG00000125398 ENSG00000100219 ENSG00000162692 ENSG00000096717 ENSG00000145782 ENSG00000163501 ENSG00000057663 PMC11839412__F3 Crucial miRNAs impacting CD133 and cell cycle regulation (By Figdraw ENSG00000138166 ENSG00000135446 PMC11839412__F4 Other pathways involved in the regulation of CD133 and the cell cycle (By Figdraw ENSG00000168283 ENSG00000140254 ENSG00000168610 PMC1808970__F3 AIRE expression is controlled by the lymphotoxin pathway ENSG00000104856 ENSG00000160224 ENSG00000173039 PMC12021630__F6 Molecular mechanism of PGRN in osteoporosis ENSG00000182578 ENSG00000170909 ENSG00000128272 ENSG00000099985 ENSG00000102575 ENSG00000131196 ENSG00000143387 PMC6482288__F3 Schematics presenting mechanisms of actions of approved and selected experimental cytokine and cytokine receptor agonists and antagonists ENSG00000115590 ENSG00000115594 PMC12021630__F4 Molecular mechanism of PGRN in intervertebral disc degeneration ENSG00000125538 ENSG00000168036 ENSG00000168646 PMC12021630__F8 Molecular mechanism of PGRN in DOP ENSG00000139219 ENSG00000157766 ENSG00000125538 ENSG00000198793 ENSG00000007171 PMC4613246__F2 AKT-independent PI3K signaling in cancer ENSG00000010671 PMC4613246__F1 PI3K/AKT signaling pathway ENSG00000002330 PMC2883337__F1 Chromaffin cell genes involved in catecholamine biosynthesis, storage, secretion and degradation ENSG00000141744 ENSG00000139190 ENSG00000150787 ENSG00000171951 ENSG00000116096 ENSG00000089199 PMC6139289__F3 A transcriptomics model of estrogen action in the ovine fetal hypothalamus: evidence for estrogenic effects of ICI 182,780 ENSG00000128272 ENSG00000115904 ENSG00000146648 PMC8700603__F3 Association between Altered Oncogenic Signaling Pathways and Overall Survival of Patients with Metastatic Colorectal Cancer ENSG00000157404 ENSG00000134982 ENSG00000115904 ENSG00000168036 ENSG00000164327 ENSG00000169032 ENSG00000047936 ENSG00000104332 ENSG00000179295 ENSG00000065717 ENSG00000122025 ENSG00000070444 ENSG00000120057 ENSG00000155011 ENSG00000136997 ENSG00000123933 ENSG00000104371 ENSG00000143622 ENSG00000108375 ENSG00000174197 ENSG00000108788 ENSG00000116990 ENSG00000077782 ENSG00000140443 ENSG00000196712 ENSG00000281178 ENSG00000157764 ENSG00000065361 ENSG00000292149 ENSG00000106483 ENSG00000106829 ENSG00000066468 ENSG00000110395 ENSG00000160867 ENSG00000050165 ENSG00000134853 ENSG00000213347 ENSG00000168646 ENSG00000146648 ENSG00000178568 ENSG00000114739 PMC3070484__F1 iNKT cell autoreactivity: what is “self” and how is it recognized? ENSG00000158473 ENSG00000134982 PMC8713748__F2 Systems biology analysis of human genomes points to key pathways conferring spina bifida risk ENSG00000213928 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000163914 ENSG00000067900 ENSG00000140464 PMC4613246__F4 PI3K-independent AKT activation in cancer ENSG00000183735 ENSG00000291971 ENSG00000101213 PMC6517498__F2 Model of canonical inflammasome activation involving regulation of autophagy induced by Ehrlichia ENSG00000239732 ENSG00000125538 ENSG00000172936 PMC6517498__F3 Model of regulation of inflammasome activation by type I IFNs in Ehrlichia infection ENSG00000239732 ENSG00000125538 ENSG00000172936 ENSG00000142166 PMC8931468__F6 Vanillin Derivatives Reverse Fusobacterium nucleatum-Induced Proliferation and Migration of Colorectal Cancer Through E-Cadherin/Beta-Catenin Pathway ENSG00000134982 ENSG00000168036 PMC6104135__F3 Schematic summary of HIF-1 signaling in hypoxia and diabetes PMC2684527__F2 Stochasticity in Protein Levels Drives Colinearity of Gene Order in Metabolic Operons of Escherichia coli ENSG00000102891 ENSG00000087250 ENSG00000198125 ENSG00000205364 PMC8419281__F2 An Update on Targeted Treatment of IgA Nephropathy: An Autoimmune Perspective ENSG00000039537 ENSG00000009724 ENSG00000166278 ENSG00000182326 PMC8319688__F4 Combining Genome-Wide Gene Expression Analysis (RNA-seq) and a Gene Editing Platform (CRISPR-Cas9) to Uncover the Selectively Pro-oxidant Activity of Aurone Compounds Against Candida albicans ENSG00000196511 ENSG00000090863 ENSG00000205795 ENSG00000124253 ENSG00000169299 PMC4960866__F1 Overview on the role of apolipoprotein E (APOE) in the three main pathways of plasma lipoprotein metabolism ENSG00000130164 ENSG00000162551 PMC9520939__F4 Meta-transcriptomic comparison of two sponge holobionts feeding on coral- and macroalgal-dissolved organic matter ENSG00000087095 ENSG00000057935 ENSG00000119471 ENSG00000109113 ENSG00000158195 ENSG00000164305 ENSG00000162923 ENSG00000155660 ENSG00000131323 ENSG00000078237 ENSG00000175104 ENSG00000105373 ENSG00000164675 PMC3931971__F1 Simplified schematic of common mutations in the Hedgehog signaling pathway leading to basal cell carcinoma from pathway activation (a), and therapeutic targets of this pathway (b) ENSG00000164690 ENSG00000128602 PMC6664527__F2 The canonical Wnt signaling pathway ENSG00000134982 ENSG00000168036 PMC6021456__F7 Interaction of LBR, Rab5, Nup205, and NXF1 in the PI3K/mTOR/AKT signaling pathway ENSG00000143815 ENSG00000169047 ENSG00000284161 ENSG00000140443 PMC5429720__F6 DEGs related to fatty acid degradation and PPARA signaling pathway between APFL and AP ENSG00000132170 PMC9017276__F8 mtDNA-STING Axis Mediates Microglial Polarization via IRF3/NFKB Signaling After Ischemic Stroke ENSG00000164430 ENSG00000118520 PMC6286780__F1 Zinc and zinc transporters are involved in FcERΙ-mediated mast cell activation ENSG00000033327 ENSG00000010810 PMC6092260__F2 MAPK and PI3K Signaling: at the Crossroads of Neural Crest Development ENSG00000033327 ENSG00000107338 ENSG00000070831 ENSG00000106070 ENSG00000163914 ENSG00000169047 ENSG00000136997 ENSG00000171791 ENSG00000099942 ENSG00000115290 PMC12221917__F2 Signaling pathway induced by TNFR2 ENSG00000104856 ENSG00000226275 ENSG00000131323 ENSG00000127191 PMC12007507__F2 Factors affecting DC maturation and function in NSCLC ENSG00000167207 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC1502396__F1 The interaction between the AR and the ErbB/MAPK pathway ENSG00000169291 ENSG00000002330 ENSG00000065361 ENSG00000177606 ENSG00000168036 PMC6583763__F1 N-linked glycosylation in the ER ENSG00000116406 ENSG00000134910 ENSG00000163902 ENSG00000163527 ENSG00000088298 PMC2517702__F3 Signal transduction in the CD95 pathway ENSG00000168040 ENSG00000164305 PMC11584862__F6 Two-step model describes the transition from naïve to primed epiblast and subsequent differentiation ENSG00000160973 ENSG00000088305 ENSG00000277641 PMC7565380__F3 Most important ncRNAs that regulate ER and HER2 receptors, drug efflux, apoptosis, DDR, cell cycle arrest, EMT, and CSCs features in BC drug resistance ENSG00000167258 ENSG00000223573 ENSG00000186272 ENSG00000169554 ENSG00000002330 ENSG00000198793 ENSG00000250506 ENSG00000168036 ENSG00000012048 ENSG00000132383 ENSG00000026508 ENSG00000146648 ENSG00000140443 PMC6568242__F2 Transcriptional Regulation of Proteasome Subunit Genes ENSG00000170967 ENSG00000197312 ENSG00000106459 PMC9699340__F3 Constitutively Active Androgen Receptor in Hepatocellular Carcinoma ENSG00000081913 ENSG00000168036 PMC6410766__F8 Signal transduction pathways that mediate migration induced by OA in breast cancer cells ENSG00000291971 ENSG00000113070 ENSG00000138798 ENSG00000146648 PMC9279298__F1 Plasmacytoid dendritic cells during COVID-19: Ally or adversary? ENSG00000088888 ENSG00000130234 ENSG00000184012 ENSG00000172936 ENSG00000276561 PMC3631463__F8 Combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation ENSG00000174125 ENSG00000110429 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000127191 PMC4834358__F1 Molecular pathways and targets of the epithelial–mesenchymal transition ENSG00000169554 ENSG00000122691 ENSG00000170558 ENSG00000288335 ENSG00000168036 ENSG00000175104 ENSG00000128602 PMC4834358__F2 Hexosamine biosynthetic pathway (HBP) and glycosylated EMT targets ENSG00000124216 ENSG00000170558 ENSG00000168036 ENSG00000128602 PMC5604128__F3 Extracellular matrix-receptor interaction signaling pathway ENSG00000136457 ENSG00000110799 ENSG00000026508 PMC7343448__F10 Mechanism of Sirt1 associated Adriamycin-resistance in DLBCL cells ENSG00000096717 PMC3895947__F4 Wide variety of glycoconjugates such as heparin sulfate proteoglycan (HSPG), chondrotin sulfate proteoglycan (CSPG), N-glycosylated cystatin C, and galectins-1 are involved in signaling pathways inducing proliferation and self-renewal of NSCs ENSG00000128342 ENSG00000168610 PMC12130087__F1 Canonical Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6167374__F4 Prominent changes upon ageing in the central carbon metabolism ENSG00000073578 ENSG00000095321 ENSG00000117118 ENSG00000163541 ENSG00000127884 ENSG00000074800 ENSG00000178537 ENSG00000092621 ENSG00000100412 ENSG00000163914 ENSG00000173599 ENSG00000100504 ENSG00000146701 ENSG00000091140 ENSG00000164778 ENSG00000062485 ENSG00000125166 ENSG00000178860 ENSG00000131473 ENSG00000067057 ENSG00000138029 ENSG00000100994 ENSG00000018510 ENSG00000105953 ENSG00000172340 ENSG00000131828 ENSG00000101365 ENSG00000110435 ENSG00000152556 PMC11876573__F6 Association network of differentially expressed genes (DEGs) in the MAPK pathway in the organ of Corti in Fkbp5−/− mice following acoustic overexposure (AO) ENSG00000011566 ENSG00000243364 ENSG00000143507 ENSG00000125538 ENSG00000152689 ENSG00000091879 PMC5900450__F2 Arachidonic acid (AA) pathway of inflammation mediators ENSG00000226275 ENSG00000158825 PMC11876573__F3 Association network of differentially expressed genes (DEGs) in the tumor necrosis factor signaling pathway in the organ of Corti in wild-type mice following acoustic overexposure (AO) ENSG00000081041 ENSG00000163739 ENSG00000173039 ENSG00000007908 ENSG00000073756 ENSG00000169245 ENSG00000128272 ENSG00000185386 ENSG00000172216 ENSG00000157227 ENSG00000177606 ENSG00000125538 ENSG00000184371 ENSG00000128342 ENSG00000285379 PMC11876573__F5 Association network of differentially expressed genes (DEGs) in the MAPK pathway in the organ of Corti in Fkbp5−/− mice before acoustic overexposure (AO) ENSG00000177606 ENSG00000163064 PMC3707916__F5 Altered Protein Networks and Cellular Pathways in Severe West Nile Disease in Mice ENSG00000142192 ENSG00000152495 ENSG00000055163 ENSG00000149294 ENSG00000189403 ENSG00000171791 ENSG00000164305 PMC11671260__F2 Multiple drug treatments that interfere with the gut microbiota ENSG00000172936 ENSG00000131096 PMC7004849__F2 Cells within the skeletal niche utilize long chain free fatty acids (LCFA) for energy generation via two complimentary cellular catabolic processes of the carnitine shuttle and Beta-oxidation ENSG00000157184 ENSG00000130164 ENSG00000113161 ENSG00000169174 PMC7723893__F1 TNFR1 activation pathway ENSG00000137275 ENSG00000102871 ENSG00000083799 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC5700458__F1 The UPR mediators have versatile roles in different cell types either in the presence of balanced or unresolved ER stress ENSG00000100219 ENSG00000168610 PMC5707529__F2 Schematic representation of the HIV-1 life cycle ENSG00000172716 ENSG00000132824 ENSG00000188816 PMC7723893__F2 TNFR2 activation pathway ENSG00000056558 ENSG00000173039 ENSG00000157625 ENSG00000131323 PMC9926998__F8 Ozonated Water Inhibits Hepatocellular Carcinoma Invasion and Metastasis by Regulating the HMGB1/NFKB/STAT3 Signaling Pathway ENSG00000087245 ENSG00000189403 ENSG00000100985 PMC9669482__F4 Ferroptosis and its role in skeletal muscle diseases ENSG00000168003 ENSG00000151012 ENSG00000167468 PMC8039952__F4 Approaches to turn a “cold tumor” into a “hot tumor” ENSG00000080166 ENSG00000121966 PMC8570409__F5 Immunopathology and Immunopathogenesis of COVID-19, what we know and what we should learn ENSG00000162711 ENSG00000164430 ENSG00000130234 PMC9603380__F12 Binding of Gamma-Glutamyl Transferase to TLR4 Signalling Allows Tissue Factor Activation in Monocytes ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC8138266__F5 Inhibition of the Wnt/Beta-catenin signaling pathway reduces autophagy levels in complement treated podocytes ENSG00000281324 ENSG00000162337 PMC5810418__F7 Small Wnt Pathway Solutions to nuclear Beta-catenin, denoted by a compartment marked ‘n’ for nucleus ENSG00000154342 ENSG00000281324 ENSG00000163251 ENSG00000134982 ENSG00000168036 PMC8419495__F4 Gene Expression Analysis Reveals Key Genes and Signalings Associated with the Prognosis of Prostate Cancer ENSG00000156049 ENSG00000050628 ENSG00000087586 ENSG00000088256 ENSG00000145386 ENSG00000182621 ENSG00000075073 ENSG00000187848 ENSG00000149295 ENSG00000093009 ENSG00000134057 ENSG00000171848 ENSG00000180616 ENSG00000136160 ENSG00000151617 ENSG00000112742 PMC5810418__F8 Large Wnt Pathway solutions ENSG00000065717 ENSG00000281324 ENSG00000134982 ENSG00000168036 ENSG00000196628 ENSG00000106829 PMC8570409__F3 Immunopathology and Immunopathogenesis of COVID-19, what we know and what we should learn ENSG00000150782 ENSG00000213928 ENSG00000134982 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000107201 ENSG00000276561 ENSG00000164342 PMC5810418__F6 Small Wnt Pathway Solutions to ubiquitinated Beta-catenin, denoted by a post-translational modification with a ‘U’ ENSG00000134982 ENSG00000113558 ENSG00000168036 ENSG00000168646 PMC6321468__F2 The non-polyphenolic compounds’ major mechanisms of action on CRC cells PMC11841418__F1 3D printed magnesium silicate/Beta-tricalcium phosphate scaffolds promote coupled osteogenesis and angiogenesis ENSG00000168036 PMC10377024__F2 Landscape of Genetic Mutations in Appendiceal Cancers ENSG00000019991 ENSG00000281324 ENSG00000157764 ENSG00000162337 ENSG00000134982 ENSG00000148400 ENSG00000138798 ENSG00000168036 ENSG00000088256 ENSG00000087460 ENSG00000124762 ENSG00000149311 ENSG00000122025 ENSG00000175054 ENSG00000074181 ENSG00000163235 ENSG00000163914 ENSG00000136997 ENSG00000197943 ENSG00000146648 PMC10377024__F3 Landscape of Genetic Mutations in Appendiceal Cancers ENSG00000122025 ENSG00000019991 ENSG00000157404 ENSG00000157764 ENSG00000163235 ENSG00000138798 ENSG00000163914 ENSG00000136997 ENSG00000197943 ENSG00000088256 ENSG00000146648 PMC10377024__F4 Landscape of Genetic Mutations in Appendiceal Cancers ENSG00000122025 ENSG00000019991 ENSG00000163235 ENSG00000138798 ENSG00000146648 PMC10377024__F5 Landscape of Genetic Mutations in Appendiceal Cancers ENSG00000149311 ENSG00000175054 ENSG00000124762 PMC10377024__F6 Landscape of Genetic Mutations in Appendiceal Cancers ENSG00000122025 ENSG00000019991 ENSG00000138798 ENSG00000121879 ENSG00000146648 PMC10377024__F7 Landscape of Genetic Mutations in Appendiceal Cancers ENSG00000281324 ENSG00000162337 ENSG00000148400 ENSG00000074181 ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000088256 ENSG00000087460 PMC10377024__F8 Landscape of Genetic Mutations in Appendiceal Cancers PMC4232733__F1 The IGF1R/mTOR signaling pathway resulting in growth and survival of the cell ENSG00000198793 ENSG00000140443 PMC6321468__F1 The polyphenols’ major mechanisms of action on colorectal cancer (CRC) cells ENSG00000168036 ENSG00000123374 PMC10957658__F3 COX-2-PGE2 signalling pathway in RCC ENSG00000076864 ENSG00000291971 ENSG00000168610 PMC11531455__F7 A5-nAChR and SOX2 signaling cascade is involved in lung cancer progression and immune escape ENSG00000168610 PMC10957658__F4 Membrane receptor mechanism of EET in RCC ENSG00000138115 ENSG00000113070 ENSG00000150907 ENSG00000171791 ENSG00000146648 ENSG00000134716 PMC4505437__F8 CFZ inhibition of PTH-induced osteoclastogenesis ENSG00000152266 ENSG00000175104 PMC4396380__F1 Reduced Tyk2 gene expression in Beta-cells due to natural mutation determines susceptibility to virus-induced diabetes ENSG00000105397 ENSG00000115415 ENSG00000157601 ENSG00000168310 ENSG00000125347 ENSG00000164342 ENSG00000142166 PMC8590789__F6 Cellular retinol binding protein-1 inhibits cancer stemness via upregulating WIF1 to suppress Wnt/Beta-catenin pathway in hepatocellular carcinoma ENSG00000156076 ENSG00000119888 ENSG00000168036 PMC10957658__F1 AA metabolism ENSG00000100473 ENSG00000226275 PMC8765545__F7 Exploring Long Non-Coding RNAs Associated with IP3/DAG Signaling Pathway as Potential Biomarkers Involved in Mast Cell Degranulation in Chronic Spontaneous Urticaria with 2-Year Follow-Up ENSG00000132906 ENSG00000002330 ENSG00000070831 PMC8193087__F1 Selenium Transport Mechanism via Selenoprotein P—Its Physiological Role and Related Diseases ENSG00000120500 ENSG00000250722 ENSG00000179988 PMC4924662__F6 FGF19 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells by modulating the GSK3B/Beta- catenin signaling cascade via FGFR4 activation ENSG00000160867 ENSG00000168036 PMC7847648__F4 PPI network construction revealed the most significant modules, and signaling pathway enrichment analyses were conducted for the module genes ENSG00000138778 ENSG00000134057 ENSG00000089685 ENSG00000123485 ENSG00000291964 ENSG00000100526 ENSG00000071539 ENSG00000093009 PMC9676466__F6 Whole genome analysis for plant growth promotion profiling of Pantoea agglomerans CPHN2, a non-rhizobial nodule endophyte ENSG00000196839 ENSG00000111837 ENSG00000198125 ENSG00000170571 PMC6538920__F1 Wnt signaling pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000177606 ENSG00000168036 PMC6538920__F2 Wnt signaling deregulation in the aging brain and in AD ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC7713372__F4 Functional profile of main vitamin D target genes ENSG00000099985 ENSG00000010327 ENSG00000163220 ENSG00000113070 ENSG00000111344 ENSG00000103569 ENSG00000167680 ENSG00000197629 ENSG00000178726 ENSG00000137801 ENSG00000019186 ENSG00000277263 ENSG00000123689 ENSG00000106178 ENSG00000135929 PMC166813__F1 The GA biosynthetic pathway in pea PMC7276919__F1 DNA Sensing in the Innate Immune Response ENSG00000239732 ENSG00000172936 ENSG00000131323 ENSG00000125347 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000057663 PMC7276919__F2 cGAS/STING pathway, a major cytosolic dsDNA sensing pathway mediating type I IFN signalingcGAS is localized close to the plasma membrane ENSG00000183735 ENSG00000164430 ENSG00000057663 PMC7276919__F4 RNA helicases, the proteins sensing dsDNA and the cross talk between dsDNA and dsRNA sensingDHX9 binds to CpG-B DNA through its DUF1605 domain and leads to NFKB pathway activation and proinflammatory cytokine release ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000174953 ENSG00000175104 ENSG00000276561 PMC4269174__F4 Complementary metabolic pathways between the brown planthopper and its yeast-like symbiont ENSG00000291791 ENSG00000188158 ENSG00000115718 PMC8538427__F11 Polar Oxy-metabolome Reveals the 4-Hydroxymandelate CoQ10 Synthesis Pathway ENSG00000132423 ENSG00000119723 ENSG00000110871 ENSG00000186603 ENSG00000158104 ENSG00000180902 ENSG00000166816 ENSG00000173085 ENSG00000167186 PMC5142153__F1 Summary of extrinsic, intrinsic and membrane stress apoptotic pathways ENSG00000149311 ENSG00000168040 PMC7605660__F7 The underlying mechanisms of zeaxanthin’s effects on signaling pathways and the induction of apoptosis in human gastric cancer cells ENSG00000143799 ENSG00000002330 ENSG00000134057 ENSG00000123374 ENSG00000047936 ENSG00000168610 PMC3984876__F1 Cilia in the nervous system: linking cilia function and neurodevelopmental disorders ENSG00000281324 ENSG00000162337 ENSG00000164690 ENSG00000128602 PMC6462325__F4 The effects of Cordyceps militaris on the levels of the main molecules in the TLR4/NFKB pathway in CKD patients ENSG00000125538 ENSG00000136869 PMC9139434__F1 Leveraging STING, Batf3 Dendritic Cells, CXCR3 Ligands, and Other Components Related to Innate Immunity to Induce A “Hot” Tumor Microenvironment That Is Responsive to Immunotherapy ENSG00000183735 ENSG00000164430 PMC6704133__F6 Resveratrol Targets Urokinase-Type Plasminogen Activator Receptor Expression to Overcome Cetuximab-Resistance in Oral Squamous Cell Carcinoma ENSG00000291971 ENSG00000163914 ENSG00000150093 ENSG00000146648 PMC8197226__F1 Emerging Roles of JNK Signaling in Drosophila Stem Cell Homeostasis ENSG00000143507 ENSG00000177606 PMC8197226__F3 Emerging Roles of JNK Signaling in Drosophila Stem Cell Homeostasis ENSG00000130294 ENSG00000138798 ENSG00000075702 PMC5459509__F12 Age-dependent electrical and morphological remodeling of the Drosophila heart caused by hERG/seizure mutations ENSG00000134982 ENSG00000163914 ENSG00000076716 PMC8369417__F6 Potential Role of RP105 in Regulation of Inflammation and Osteoclastogenesis During Inflammatory Diseases ENSG00000177455 ENSG00000095585 ENSG00000172936 ENSG00000131196 ENSG00000135605 ENSG00000010671 PMC4474402__F5 Dysregulation of astrocyte extracellular signaling in Costello syndrome ENSG00000111145 ENSG00000019549 ENSG00000100941 ENSG00000114315 ENSG00000162599 PMC8369417__F5 Potential Role of RP105 in Regulation of Inflammation and Osteoclastogenesis During Inflammatory Diseases ENSG00000239732 ENSG00000131196 ENSG00000010671 PMC7912299__F4 Pathways to the generation of cytosolic and mitochondrial citrate and its utilization ENSG00000131473 ENSG00000100412 ENSG00000113161 ENSG00000079432 ENSG00000115419 ENSG00000141485 PMC8369417__F3 Potential Role of RP105 in Regulation of Inflammation and Osteoclastogenesis During Inflammatory Diseases ENSG00000174125 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000131196 PMC8369417__F1 Potential Role of RP105 in Regulation of Inflammation and Osteoclastogenesis During Inflammatory Diseases ENSG00000095585 ENSG00000170909 ENSG00000070831 ENSG00000164935 ENSG00000134215 ENSG00000197943 ENSG00000175104 ENSG00000131196 ENSG00000167106 ENSG00000010671 ENSG00000143387 PMC7912299__F8 Mitochondrial and cytosolic pathways leading to D2-L2 hydroxyglutaric acid (D-L-2HG) accumulation (see text for explanation) ENSG00000092621 ENSG00000087299 ENSG00000079432 ENSG00000180902 ENSG00000146701 PMC6405411__F6 Signaling pathways activated by the LH surge in ovulatory follicles ENSG00000065361 ENSG00000109321 ENSG00000124882 ENSG00000138039 PMC7846784__F1 Perspectives on skeletal muscle stem cells ENSG00000019991 ENSG00000107562 ENSG00000118263 ENSG00000198793 ENSG00000189403 ENSG00000121966 ENSG00000106546 ENSG00000179295 PMC4474305__F9 The differential subversion of type I IFN and mitochondrial apoptotic pathway by LCMV ENSG00000183735 ENSG00000088888 ENSG00000131323 PMC8627558__F2 Dynamic and cell-specific transport networks for intracellular copper ions ENSG00000123191 ENSG00000177556 PMC4992261__F4 5 nM PhIP activates STAT3-mediated transcriptional regulation ENSG00000288411 ENSG00000133110 ENSG00000162551 ENSG00000118515 ENSG00000265972 ENSG00000168610 ENSG00000136859 PMC6405411__F8 PGE2 synthesis, receptors, transport, and metabolism in granulosa cells ENSG00000050628 ENSG00000138039 ENSG00000125384 ENSG00000148344 ENSG00000164120 ENSG00000073756 ENSG00000160951 PMC12153588__F5 Microtubule dynamics regulated by interconnected pathways coordinating polymerization and depolymerization ENSG00000134057 ENSG00000166851 PMC12153588__F6 PI3K-Akt pathway’s role in coordinating cytoskeletal dynamics during axon guidance by regulating microtubules, intermediate filaments, and actin networks ENSG00000106683 ENSG00000099942 ENSG00000047849 ENSG00000182541 PMC4847623__F1 Sphingolipid biosynthetic pathway ENSG00000228278 ENSG00000229314 ENSG00000135517 PMC12153588__F4 Microfilament signaling pathway ENSG00000106683 ENSG00000070831 ENSG00000182541 PMC4058013__F3 KLK5 protease suppresses breast cancer by repressing the mevalonate pathway ENSG00000130164 ENSG00000172893 ENSG00000163914 ENSG00000113161 ENSG00000099377 ENSG00000169174 PMC8423867__F3 N-terminal acetylation and lysine acetylation ENSG00000094631 ENSG00000171320 ENSG00000187531 ENSG00000196591 ENSG00000147133 ENSG00000077463 ENSG00000100429 ENSG00000142082 ENSG00000172352 ENSG00000283100 ENSG00000160294 ENSG00000141446 ENSG00000108840 ENSG00000292096 ENSG00000171720 ENSG00000147099 ENSG00000061273 ENSG00000124523 ENSG00000096717 ENSG00000089163 PMC8423867__F4 The protein acetylation in regulation of cancer-associated events ENSG00000145604 ENSG00000149311 ENSG00000213928 ENSG00000150907 ENSG00000124253 PMC9157426__F3 Therapeutic Effect of SCFA-Mediated Regulation of the Intestinal Environment on Obesity ENSG00000167772 ENSG00000131096 PMC8900014__F1 Viral infections in humans and mice with genetic deficiencies of the type I IFN response pathway ENSG00000159128 ENSG00000213928 ENSG00000105397 ENSG00000185436 ENSG00000027697 ENSG00000142166 PMC9420268__F1 Osteosarcoma with cell-cycle and fibroblast growth factor genomic alterations: case report of Molecular Tumor Board combination strategy resulting in long-term exceptional response ENSG00000118972 ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000118971 PMC4773096__F1 Dynamic Modeling and Analysis of the Cross-Talk between Insulin/AKT and MAPK/ERK Signaling Pathways ENSG00000198793 PMC2926987__F3 Reconstructed antioxidant regulation pathway of detoxifying proteins ENSG00000185022 ENSG00000128272 ENSG00000116044 ENSG00000177606 ENSG00000198517 ENSG00000116791 ENSG00000127948 ENSG00000197063 ENSG00000079999 PMC5866353__F1 Compiled summary of signaling pathways activated by prostanoid receptor PGE2 receptor 2 (EP2) in osteocytes, neurodegenerative diseases, and colon cancer (see text for details) ENSG00000019991 ENSG00000291971 ENSG00000168036 ENSG00000146648 PMC12067647__F5 The cytokine-cytokine receptor interaction pathway in IIM patients with/without anti-MDA5+ autoantibodies ENSG00000123999 ENSG00000104899 ENSG00000107562 ENSG00000117400 ENSG00000163734 ENSG00000113520 ENSG00000145777 ENSG00000128342 ENSG00000026103 PMC3628025__F7 Proposed model suggesting that TGFB increases COX-2 levels and PGE2 secretion in prostate cancer cells and both TGFB and PGE2 activate PI3K/AKT/mTOR signaling pathway ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC6447799__F3 Leptin signaling pathways ENSG00000198793 ENSG00000168610 PMC4870076__F6 Potential mechanism underlying Qinggan Huoxue Recipe-mediated inhibition of epithelial-to-mesenchymal transition in alcoholic liver fibrosis rats PMC3636761__F1 PI3K signaling pathway and the downstream targets of Akt ENSG00000002330 PMC6270750__F1 Astragaloside biosynthetic pathway ENSG00000197429 ENSG00000167508 PMC6175639__F8 Schematic Illustrating Potential Pathways for Glucose Utilization and Energy Production by Tendon Cells ENSG00000138798 PMC5831777__F3 Hh signaling within the developing TMJ ENSG00000139219 ENSG00000106571 ENSG00000125398 ENSG00000117425 ENSG00000128602 ENSG00000163501 PMC10152377__F1 Somatic Variants Activating Ras/Raf/Mitogen-Activated Protein Kinase (MAPK) Pathway Genes in Mesial Temporal Lobe Epilepsy ENSG00000196712 PMC10346897__F4 Mechanism by which PUFAs suppress cholesterol synthesis via inhibition of the signaling pathway of sterol regulatory element-binding protein-1 (SREBP-1) [74] ENSG00000138075 ENSG00000186480 ENSG00000160179 ENSG00000143921 ENSG00000026103 PMC5958547__F1 New Opportunities and Challenges to Defeat Cancer Stem Cells ENSG00000163464 ENSG00000128602 ENSG00000168610 PMC10845654__F8 Working model ENSG00000182749 PMC4407014__F4 An incomplete engagement of the TCR pathway differentiates BT-061 from other anti-CD4 mAbs ENSG00000132478 PMC2710138__F8 Feedback inhibition of the phosphatidylinositol 3—kinase (PI3K) pathway ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC9929207__F4 MAPKAPK2-centric transcriptome profiling reveals its major role in governing molecular crosstalk of IGFBP2, MUC4, and PRKAR2B during HNSCC pathogenesis ENSG00000162889 ENSG00000128016 ENSG00000066044 ENSG00000111837 PMC2710138__F2 Phosphatidylinositol 3—kinase (PI3K) signaling pathway ENSG00000002330 ENSG00000070831 PMC4900191__F2 Regenerative Medicine: Charting a New Course in Wound Healing ENSG00000274382 ENSG00000136997 ENSG00000083799 PMC6347283__F1 Representation of signaling pathways upstream of MTORC1 ENSG00000168209 ENSG00000169047 ENSG00000145979 ENSG00000155876 PMC6347283__F2 Effectors downstream of MTORC1 ENSG00000100811 ENSG00000065911 ENSG00000284161 ENSG00000167658 ENSG00000171791 ENSG00000168610 ENSG00000070669 ENSG00000132170 ENSG00000109819 ENSG00000128272 ENSG00000092621 ENSG00000173599 ENSG00000136997 ENSG00000089163 ENSG00000115419 ENSG00000084774 PMC8894463__F8 Schematic illustrating the mechanism by which TRIM45 regulates cerebral I/R injury by activating NFKB signaling in microglia ENSG00000134253 PMC7509400__F2 Immune functions of GD T cells in cancers ENSG00000125538 ENSG00000231179 ENSG00000204520 ENSG00000026103 PMC6068089__F9 Schematic depicting neuroprotective roles of BRCA1 towards I/R injury ENSG00000012048 ENSG00000167468 PMC3222593__F2 Pathway Studio® (Ariadne Genomics) was used to identify known relationships among human homologues of the genes identified as differentially regulated by ANOVA ENSG00000136997 ENSG00000167701 PMC8072347__F1 OSCAR Signaling in Osteoclastogenesis and Bone Disease ENSG00000095585 ENSG00000291971 ENSG00000175104 ENSG00000131196 ENSG00000135605 ENSG00000010671 PMC4594952__F3 Concise review on the current understanding of pancreatic cancer stem cells ENSG00000106571 ENSG00000119888 ENSG00000134982 ENSG00000026508 ENSG00000168036 ENSG00000164690 ENSG00000114315 PMC6788756__F2 Functions of the calcineurin signaling pathway in S ENSG00000101871 ENSG00000136100 ENSG00000159263 ENSG00000112246 ENSG00000117906 ENSG00000114315 ENSG00000176153 PMC11523277__F1 Effect of ubiquitination imbalance on osteosarcoma cells and its clinical application ENSG00000132109 ENSG00000183763 ENSG00000166233 ENSG00000164197 ENSG00000163462 ENSG00000162607 PMC11523277__F2 Ubiquitin-mediated regulation of key signaling pathways in tumor cells ENSG00000132109 ENSG00000108395 ENSG00000114125 ENSG00000077152 ENSG00000036672 ENSG00000172046 ENSG00000121067 ENSG00000158290 ENSG00000291527 ENSG00000133606 ENSG00000077254 ENSG00000140455 ENSG00000078747 ENSG00000183579 ENSG00000108375 ENSG00000125850 ENSG00000166436 ENSG00000109670 PMC8471964__F6 Idebenone Decreases AB Pathology by Modulating RAGE/Caspase-3 Signaling and the AB Degradation Enzyme NEP in a Mouse Model of AD ENSG00000142192 PMC11523277__F3 Dysregulated ubiquitination pathway drives osteosarcoma malignancy ENSG00000132109 ENSG00000124422 ENSG00000162711 ENSG00000183763 ENSG00000198793 ENSG00000168036 ENSG00000091542 ENSG00000277273 ENSG00000079999 ENSG00000145604 ENSG00000214114 ENSG00000166233 ENSG00000164197 ENSG00000163462 ENSG00000121410 ENSG00000123989 ENSG00000132646 ENSG00000162607 ENSG00000026508 ENSG00000100479 ENSG00000291761 ENSG00000096717 PMC3621012__F2 Regulation of miRNA biogenesis and turnover in the immune system ENSG00000136997 ENSG00000175104 ENSG00000184216 PMC5072418__F1 Proposed Pd0/PdII catalytic cycle for aryl fluorination ENSG00000258429 ENSG00000004848 PMC5918594__F4 Proinflammatory challenge and anti‐inflammatory drugs on expression of genes related to tryptophan and kynurenine metabolism ENSG00000168003 ENSG00000125166 ENSG00000129167 ENSG00000162882 ENSG00000112394 ENSG00000103257 ENSG00000183077 PMC5371895__F1 Schematic metabolic model showing important pathways after proliferation of Streptococcus suis serotype 2 in porcine blood (A) and cerebrospinal fluid (CSF) (B) ENSG00000069482 ENSG00000122966 ENSG00000150787 PMC2796203__F1 Targeting the Transforming Growth FactorB Signaling Pathway in Human Cancer ENSG00000023734 ENSG00000070831 ENSG00000138798 ENSG00000163914 PMC2796203__F2 Targeting the Transforming Growth FactorB Signaling Pathway in Human Cancer PMC11523277__F4 Potential of ubiquitination modulation in osteosarcoma treatment ENSG00000063978 ENSG00000163462 ENSG00000198171 ENSG00000162607 ENSG00000183579 ENSG00000070950 ENSG00000124209 ENSG00000130726 ENSG00000109670 PMC3287202__F6 Overview of pre-miRNA processing ENSG00000131914 ENSG00000100697 ENSG00000113360 ENSG00000123908 PMC11833784__F5 Schematic representations of energy metabolites and enzymes involved in glycolysis, TCA cycle, ETC and AMPK pathway in ileum of layer pullets ENSG00000106459 ENSG00000062485 PMC6916690__F2 Signaling pathways and cross talk, regulated by E-cadherin ENSG00000198793 ENSG00000146648 PMC12035655__F10 Novel Wnt/Beta-catenin signaling gene signature for progression and metastasis of gastric cancer ENSG00000071564 ENSG00000168036 ENSG00000106624 PMC6505469__F10 Resveratrol reduces liver endoplasmic reticulum stress and improves insulin sensitivity in vivo and in vitro ENSG00000128272 ENSG00000101255 PMC2671916__F6 Novel functional modules with dynamic gene expression changes potentially linked to prion pathophysiology: (A) androgen metabolism, (B) iron metabolism, (C) arachidonate/phospholipid metabolism ENSG00000010704 ENSG00000226275 ENSG00000099377 ENSG00000133805 PMC3618522__F1 Molecular Pathways: Current Role and Future Directions of the Retinoic Acid Pathway In Cancer Prevention and Treatment PMC3913495__F1 IL-6 exerts its pleiotropic activity by activation of gp130 through its binding to transmembrane or soluble IL-6 receptor ENSG00000168610 ENSG00000132693 PMC3618522__F2 Molecular Pathways: Current Role and Future Directions of the Retinoic Acid Pathway In Cancer Prevention and Treatment ENSG00000143799 PMC6963578__F2 Schematic diagram of interactions between arenavirus proteins and host innate immune machinery ENSG00000183735 ENSG00000144895 PMC5742799__F2 Hypothetical model for the proposed anti-inflammatory role of MUC1 in response to P ENSG00000163235 ENSG00000187554 ENSG00000172936 ENSG00000185591 ENSG00000175104 ENSG00000146648 ENSG00000184216 PMC5759160__F3 Schematics of the Wnt/Beta-catenin signalling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8134663__F2 Unraveling the Role of the Apical Papilla During Dental Root Maturation ENSG00000162552 ENSG00000154342 ENSG00000066468 ENSG00000281324 ENSG00000162337 ENSG00000164161 ENSG00000134982 ENSG00000168036 ENSG00000152591 ENSG00000164690 ENSG00000185269 ENSG00000077782 PMC7697917__F8 BDNF pathway ENSG00000196591 ENSG00000173039 ENSG00000168610 ENSG00000106546 PMC5849167__F5 Ang-2 up-regulating EMT and facilitating lung cancer metastasis ENSG00000134086 ENSG00000074800 ENSG00000163235 ENSG00000148926 ENSG00000198793 ENSG00000007171 PMC8132202__F4 Risk prediction model of gene signatures in ovarian cancer through bagging of GA-XGBoost models ENSG00000109452 ENSG00000263639 ENSG00000112964 ENSG00000137501 ENSG00000153823 ENSG00000134215 ENSG00000164694 ENSG00000123572 ENSG00000173376 ENSG00000182263 ENSG00000170962 ENSG00000038427 ENSG00000099139 ENSG00000147041 ENSG00000141753 ENSG00000166482 ENSG00000124440 ENSG00000115461 PMC5504240__F1 Circadian metabolites have pleiotropic mechanisms by which to maintain cellular rhythmicity ENSG00000198793 ENSG00000166073 ENSG00000132326 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000082212 PMC3133259__F1 The CoA biosynthetic pathway ENSG00000138621 ENSG00000127125 PMC3248184__F1 YB-1 drives preneoplastic progression: Insight into opportunities for cancer prevention ENSG00000291971 PMC5352107__F4 Triple-negative breast cancer: is there a treatment on the horizon? ENSG00000198793 ENSG00000146648 PMC8479803__F1 Vascular smooth muscle cells in atherosclerosis: time for a re-assessment ENSG00000135218 ENSG00000125398 ENSG00000118526 ENSG00000173611 ENSG00000129226 ENSG00000141052 ENSG00000136826 PMC7486896__F8 Exosomal lncRNA DOCK9-AS2 derived from cancer stem cell-like cells activated Wnt/Beta-catenin pathway to aggravate stemness, proliferation, migration, and invasion in papillary thyroid carcinoma ENSG00000087245 ENSG00000137673 ENSG00000168036 ENSG00000185591 PMC8357478__F9 Tianma Formula Alleviates Dementia via ACER2-Mediated Sphingolipid Signaling Pathway Involving AB PMC5466513__F1 Autophagy in UV damage response ENSG00000177169 ENSG00000152348 ENSG00000198382 ENSG00000144848 ENSG00000145782 ENSG00000285069 ENSG00000057663 PMC8307504__F6 Nuclear Envelope Integrity in Health and Disease: Consequences on Genome Instability and Inflammation ENSG00000183735 ENSG00000164430 PMC5571543__F8 Proposed mechanism of ESA‐mediated downregulation of Foxp3 in regulatory T cells ENSG00000049768 PMC4263025__F1 RAF fusion genes in prostate and gastric cancer and melanoma ENSG00000157764 ENSG00000177674 ENSG00000104413 PMC8430084__F2 Neutrophil extracellular traps (NETs): the role of inflammation and coagulation in COVID-19 ENSG00000281244 ENSG00000160752 ENSG00000003436 ENSG00000110799 ENSG00000122194 PMC6592994__GA Biological role of MALAT1 in cyclin D1, miR-363-3p and Mcl1 gene regulations ENSG00000134982 ENSG00000168036 PMC3313594__F3 Targeting blood–brain barrier changes during inflammatory pain: an opportunity for optimizing CNS drug delivery ENSG00000170365 PMC9138253__F3 Cross-Talk between Wnt Signaling and Src Tyrosine Kinase ENSG00000038382 ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000070831 ENSG00000291971 ENSG00000134982 ENSG00000185483 ENSG00000168036 PMC3313594__F5 Targeting blood–brain barrier changes during inflammatory pain: an opportunity for optimizing CNS drug delivery ENSG00000170365 PMC1817809__F1 AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues ENSG00000198793 PMC4609654__F1 The Wnt signaling pathway with selected inhibitors ENSG00000134982 ENSG00000169884 ENSG00000168036 ENSG00000108375 ENSG00000125084 PMC9138253__F6 Cross-Talk between Wnt Signaling and Src Tyrosine Kinase ENSG00000281324 ENSG00000162337 ENSG00000291971 ENSG00000168036 ENSG00000067900 PMC1817809__F2 AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance ENSG00000242689 ENSG00000198793 PMC3322992__F8 Pathways required for the role of CDCP1 in EGF/EGFR-induced cell morphological changes and increased cell migration ENSG00000138798 ENSG00000163814 ENSG00000146648 PMC8926078__F1 Non-Coding RNAs in Autophagy During Carcinogenesis ENSG00000177169 ENSG00000110497 ENSG00000152348 ENSG00000123395 ENSG00000198382 ENSG00000083290 ENSG00000126775 ENSG00000136874 ENSG00000057663 ENSG00000144848 ENSG00000189403 ENSG00000145782 ENSG00000146648 PMC6828502__F1 Dual pathway for metabolic engineering of Escherichia coli to produce the highly valuable hydroxytyrosol PMC2735908__F8 Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway ENSG00000126562 ENSG00000143867 ENSG00000005882 ENSG00000060237 ENSG00000118515 ENSG00000080166 PMC12230486__F4 Metabolic Adaptations and Therapies in Cardiac Hypoxia ENSG00000180210 ENSG00000105251 ENSG00000136997 ENSG00000196092 ENSG00000078237 ENSG00000089163 ENSG00000115419 ENSG00000159399 PMC6499784__F4 Schematic representation of a proposed model of the TBS pathway interaction with PET ENSG00000066926 ENSG00000173599 PMC8249349__F1 Metabolic alterations in pancreatic cancers ENSG00000125166 ENSG00000065833 ENSG00000197713 ENSG00000122966 ENSG00000172005 ENSG00000153574 ENSG00000115419 ENSG00000159399 PMC8249349__F2 Pancreatic cancers rely on autophagy and lysosomal scavenging ENSG00000177169 ENSG00000123395 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 ENSG00000136874 PMC9068506__F3 Association of Gut Microbiota with Inflammatory Bowel Disease and COVID-19 Severity: A Possible Outcome of the Altered Immune Response ENSG00000213928 ENSG00000088888 ENSG00000130234 ENSG00000172936 PMC6854743__F8 Signaling pathway of the Akt + diuron-induced glioma ENSG00000132646 ENSG00000276043 PMC7266824__F2 Ibrutinib in Chronic Lymphocytic Leukemia: Clinical Applications, Drug Resistance, and Prospects ENSG00000104365 ENSG00000100906 ENSG00000186716 ENSG00000198793 ENSG00000269335 ENSG00000173039 ENSG00000197943 ENSG00000168610 ENSG00000010671 PMC12230486__F1 Under Hypoxic Conditions, The Energy Metabolism of Cardiomyocytes ChangesMany of the discussed pathways show protection against ischemia-reperfusion injury (IRI) (green arrows) or are protective if blocked (red arrows) ENSG00000180210 ENSG00000105251 ENSG00000136997 ENSG00000196092 ENSG00000078237 ENSG00000089163 ENSG00000115419 PMC11352684__F4 TRIM proteins in the cellular signaling pathway of MAFLD ENSG00000132109 ENSG00000050730 ENSG00000213186 ENSG00000112343 ENSG00000169710 ENSG00000221869 ENSG00000171206 ENSG00000141569 ENSG00000167468 ENSG00000119283 ENSG00000157625 ENSG00000007384 ENSG00000106266 ENSG00000122779 ENSG00000096717 ENSG00000221926 PMC12230486__F2 Metabolic Adaptations and Therapies in Cardiac Hypoxia ENSG00000135218 PMC5722516__F7 Inhibitors of the PI3K/mTOR pathway prevent STAT5 phosphorylation in JAK2V617F mutated cells through PP2A/CIP2A axis ENSG00000198793 ENSG00000163507 PMC12230486__F3 Metabolic Adaptations and Therapies in Cardiac Hypoxia ENSG00000153208 ENSG00000135218 ENSG00000112715 ENSG00000145850 ENSG00000150630 PMC9654020__F1 Looking into Endoplasmic Reticulum Stress: The Key to Drug-Resistance of Multiple Myeloma? ENSG00000128272 ENSG00000156026 ENSG00000198793 ENSG00000110931 ENSG00000100219 ENSG00000127191 PMC10572085__F2 Signaling pathways of the CD44 intracellular domain (CD44-ICD) under hypoxia ENSG00000122882 ENSG00000114268 ENSG00000026508 PMC10572085__F3 Signaling pathway activated by HA-CD44 interaction ENSG00000070831 ENSG00000163914 ENSG00000026508 ENSG00000146648 PMC6130388__F6 Schematic of proposed model ENSG00000125538 PMC4850468__F1 Molecular Mechanisms of EndoMT ENSG00000105664 ENSG00000148400 ENSG00000086991 ENSG00000164690 ENSG00000128602 PMC10572085__F5 HA-CD44 binding-activated signaling pathways ENSG00000026508 ENSG00000171791 PMC8485759__F4 Purine synthesis and its dependency on mitochondrial metabolism ENSG00000128050 ENSG00000100714 PMC12211383__F1 Sources and metabolic functions of serine ENSG00000284320 ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC11815735__F9 Proposed mechanism elucidating the involvement of EBV in oral cancers encompasses the regulation of host cellular lncRNA LINC00944 ENSG00000169245 ENSG00000115415 ENSG00000138755 ENSG00000125347 PMC5630322__F7 Serine 207 phosphorylated lysyl-tRNA synthetase predicts disease-free survival of non-small-cell lung carcinoma ENSG00000178860 ENSG00000138798 ENSG00000146648 PMC7641864__F7 Metabolomics analysis of the mechanisms of hUCMSC treatment for POI ENSG00000160224 ENSG00000158874 ENSG00000254550 PMC10388466__F7 Peptidase inhibitor (PI16) impairs bladder cancer metastasis by inhibiting NFKB activation via disrupting multiple-site ubiquitination of NEMO ENSG00000164530 PMC7026421__F1 Rho-ROCK signaling mediates entotic cell death in tumor ENSG00000112977 ENSG00000163914 PMC7586277__F7 Pathway leading to phagocytosis of senescent AD-MSCs ENSG00000162711 ENSG00000150782 ENSG00000170458 ENSG00000136869 ENSG00000265972 PMC6721448__F3 BRAF-mediated signaling in normal and cancer cells ENSG00000019991 ENSG00000157764 ENSG00000135446 ENSG00000198793 ENSG00000146648 ENSG00000196712 PMC3196116__F10 Proposed model shows the requirement of the IL-4RAlpha-Jak2-mediated signaling pathway for IL-13-induced M2 gene expression in human monocytes/macrophages ENSG00000135218 ENSG00000115415 ENSG00000168610 PMC9381384__F1 Clinical, phenotypic and genetic landscape of case reports with genetically proven inherited disorders of vitamin B12 metabolism: A meta-analysis ENSG00000119688 ENSG00000151611 ENSG00000168288 ENSG00000132763 ENSG00000168216 ENSG00000116984 PMC7779201__F3 Hypothesis of Apatinib acquired drug‐ resistance mechanism caused by WRN point mutation ENSG00000165392 ENSG00000047936 PMC8763889__F2 Carcinogenic mechanism of TFF3 ENSG00000002330 ENSG00000082175 ENSG00000160180 ENSG00000170558 ENSG00000198793 ENSG00000163914 ENSG00000164362 ENSG00000171791 ENSG00000168610 ENSG00000146648 ENSG00000174482 ENSG00000121966 PMC5773092__F7 Histological subtypes of mouse mammary tumors reveal conserved relationships to human cancers ENSG00000157764 ENSG00000164690 PMC9114637__F1 Mechanically-Activated Ion Channels Piezo1, Piezo2, and TRPV4 in Chondrocyte Mechanotransduction and Mechano-Therapeutics for Osteoarthritis ENSG00000157766 ENSG00000115594 ENSG00000103335 PMC3099033__F9 Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling PMC8956597__F3 Temporal dynamics from phosphoproteomics using endoscopic biopsy specimens provides new therapeutic targets in stage IV gastric cancer ENSG00000002330 ENSG00000157764 ENSG00000291971 ENSG00000198793 ENSG00000108443 ENSG00000099942 ENSG00000124762 ENSG00000160691 ENSG00000175634 ENSG00000117020 ENSG00000148660 ENSG00000149269 ENSG00000177606 ENSG00000136997 ENSG00000071051 ENSG00000143322 ENSG00000137843 ENSG00000145349 ENSG00000146648 ENSG00000130669 PMC5499671__F3 TGFB regulation of T cells in multiple sclerosis ENSG00000049768 PMC8956597__F4 Temporal dynamics from phosphoproteomics using endoscopic biopsy specimens provides new therapeutic targets in stage IV gastric cancer ENSG00000002330 ENSG00000157764 ENSG00000291971 ENSG00000198793 ENSG00000115904 ENSG00000108443 ENSG00000099942 ENSG00000124762 ENSG00000160691 ENSG00000175634 ENSG00000117020 ENSG00000148660 ENSG00000173757 ENSG00000149269 ENSG00000177606 ENSG00000136997 ENSG00000071051 ENSG00000143322 ENSG00000137843 ENSG00000145349 ENSG00000146648 ENSG00000130669 PMC8956597__F5 Temporal dynamics from phosphoproteomics using endoscopic biopsy specimens provides new therapeutic targets in stage IV gastric cancer ENSG00000002330 ENSG00000157764 ENSG00000291971 ENSG00000198793 ENSG00000115904 ENSG00000108443 ENSG00000099942 ENSG00000124762 ENSG00000160691 ENSG00000175634 ENSG00000117020 ENSG00000148660 ENSG00000149269 ENSG00000177606 ENSG00000136997 ENSG00000071051 ENSG00000143322 ENSG00000137843 ENSG00000145349 ENSG00000146648 ENSG00000130669 PMC6281578__F8 LncRNA DANCR upregulates PI3K/AKT signaling through activating serine phosphorylation of RXRA ENSG00000121879 PMC2774878__F2 The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of pulmonary fibrosis ENSG00000134086 ENSG00000107562 ENSG00000138798 ENSG00000121966 PMC3195753__F3 Comparative analysis of plastid transcriptomes in cucumber ENSG00000223367 ENSG00000115268 ENSG00000173599 ENSG00000142534 ENSG00000188846 ENSG00000171863 ENSG00000125656 ENSG00000116251 ENSG00000130255 PMC5988607__F3 Regulators of MST1 and MST2 ENSG00000198670 ENSG00000166278 ENSG00000150457 ENSG00000131023 PMC7047199__F1 Radiation-induced effects on pathways related to mitochondria in cardiac cells ENSG00000170899 ENSG00000247077 ENSG00000079999 PMC8921539__F4 Hypoxia and chronic kidney disease ENSG00000134086 ENSG00000187266 ENSG00000146648 ENSG00000079999 PMC10867724__F4 Demonstration of the TNF signaling pathway and the target to be tested ENSG00000167207 ENSG00000078747 ENSG00000102871 ENSG00000177606 ENSG00000007908 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000164305 PMC4349561__F2 Pathway analyses of direct interactions among transcripts mediated by P4 in the ovary ENSG00000130340 ENSG00000082175 ENSG00000065526 ENSG00000149269 ENSG00000100345 ENSG00000076604 PMC4349561__F3 Pathway analyses of A) tumor protein p53 (TP53) B) E2F transcription factor 1 (E2F1), and C) miRNA 124-1 ENSG00000008710 ENSG00000101751 ENSG00000131747 ENSG00000101057 ENSG00000076604 PMC6198132__F3 Hypothetical scheme for the unfolded protein response-induced signaling cascade in MANF-deficient beta cells ENSG00000128272 ENSG00000144895 ENSG00000101255 ENSG00000100219 ENSG00000127191 PMC3444501__F4 Therapeutic Effects of Astragaloside IV on Myocardial Injuries: Multi-Target Identification and Network Analysis ENSG00000157404 ENSG00000109743 ENSG00000138798 ENSG00000173083 ENSG00000158517 ENSG00000132693 ENSG00000168610 ENSG00000163631 ENSG00000180210 ENSG00000224320 ENSG00000196549 ENSG00000169750 ENSG00000163235 ENSG00000130234 ENSG00000102245 ENSG00000188130 ENSG00000146648 ENSG00000196712 PMC9104445__F8 Piperine Provides Neuroprotection against Kainic Acid-Induced Neurotoxicity via Maintaining NGF Signalling Pathway ENSG00000137673 ENSG00000100985 PMC4947819__F2 SOX2-mediated sensing of cytoplasmic DNA and the associated signaling pathway in neutrophils ENSG00000125538 PMC8959092__F3 Repurposed drugs targets in ovarian cancer ENSG00000198793 PMC7894323__F6 Infigratinib and ribociclib in inducing differentiation and preventing dedifferentiation ENSG00000125398 ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 PMC11629812__F6 S‐Nitrosylation of NOTCH1 Regulates Mesenchymal Stem Cells Differentiation Into Hepatocyte‐Like Cells by Inhibiting Notch Signalling Pathway ENSG00000148400 ENSG00000114315 PMC8523946__F3 MiR-873-5p: A Potential Molecular Marker for Cancer Diagnosis and Prognosis ENSG00000100558 ENSG00000161921 ENSG00000134982 ENSG00000078399 ENSG00000082512 ENSG00000198793 ENSG00000131507 ENSG00000168036 ENSG00000100985 ENSG00000127191 ENSG00000161999 ENSG00000104723 PMC12112582__F4 Illustration shows the GPCR signaling pathway exploited by neuropeptides in insects to transmit signals regulating various physiological processes, including the mating behaviors ENSG00000214285 ENSG00000115718 ENSG00000258429 PMC8521155__F1 The Complement System by Neoplastic Disease of the Central Nervous System ENSG00000196352 ENSG00000117335 ENSG00000166278 PMC4224453__F10 miR-18a Inhibits CDC42 and Plays a Tumour Suppressor Role in Colorectal Cancer Cells ENSG00000070831 ENSG00000040199 PMC7877185__F3 Competing endogenous RNAs (ceRNAs) and the signaling pathways involved in lung cancer cell invasion and migration ENSG00000124140 ENSG00000087245 ENSG00000169554 ENSG00000172927 ENSG00000137673 ENSG00000091656 ENSG00000110514 ENSG00000138798 ENSG00000198793 ENSG00000170558 ENSG00000168036 ENSG00000100744 ENSG00000112715 ENSG00000102172 ENSG00000143537 ENSG00000141867 ENSG00000150907 ENSG00000100985 ENSG00000146648 PMC7877185__F1 Competing endogenous RNAs (CeRNAs) and the signaling pathways involved in lung cancer cell proliferation ENSG00000145604 ENSG00000112242 ENSG00000138798 ENSG00000132646 ENSG00000169047 ENSG00000136997 ENSG00000171848 ENSG00000123374 ENSG00000083799 ENSG00000105810 ENSG00000145386 ENSG00000282899 PMC7404143__F5 Roles of NRP2 in SMC phenotypic switching ENSG00000118257 PMC3084021__F1 Conservation of the RB and Hippo signaling pathways in humans and fruit flies ENSG00000135446 ENSG00000123374 ENSG00000112118 ENSG00000150457 PMC6441712__F7 Effects of SIRT2/cMYC pathway in CCA cells.SIRT2 and cMYC reprogrammed the metabolism of CCA cells by up-regulating downstream p-PHDA1 and PHGDH/PSAT1/PSPH ENSG00000092621 ENSG00000146733 ENSG00000131828 ENSG00000283100 PMC7404143__F3 Endothelial cell NRP2-mediated signalling pathways ENSG00000167772 ENSG00000112715 ENSG00000118257 ENSG00000126458 PMC523224__F6 Metabolic pathway leading to generation and detoxification of MG ENSG00000197713 PMC8293794__F1 New developments implicating IL-21 in autoimmune disease ENSG00000111537 ENSG00000115415 ENSG00000103522 ENSG00000168610 PMC8738868__F4 Emerging commonalities of circRNA-mediated signaling pathways ENSG00000134982 ENSG00000168036 PMC8293794__F2 New developments implicating IL-21 in autoimmune disease ENSG00000115415 ENSG00000105639 PMC6052012__F4 Metabolic construction of the putative pathway for AOM coupled to Fe(III) reduction in “M ENSG00000166278 ENSG00000116984 PMC4835044__F8 Schematic depicting the Arg-auxotrophic response ENSG00000167601 ENSG00000157764 PMC9413556__F1 Targeting IRE1Alpha-JNK-c-Jun/AP-1-sEH Signaling Pathway Improves Myocardial and Coronary Endothelial Function Following Global Myocardial Ischemia/Reperfusion ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC3591455__F5 Essential Role of the Zinc Transporter ZIP9/SLC39A9 in Regulating the Activations of Akt and Erk in B-Cell Receptor Signaling Pathway in DT40 Cells ENSG00000177455 ENSG00000095585 ENSG00000010671 PMC6865334__F8 Potential pathway for enhanced invasion upon mechanical stimulation ENSG00000106683 ENSG00000149269 PMC10991915__F4 Physiological and transcriptome analysis elucidates the metabolic mechanism of versatile Porphyridium purpureum under nitrogen deprivation for exopolysaccharides accumulation ENSG00000197713 ENSG00000122966 ENSG00000172005 PMC5385655__F6 Schematic representation of the effect of S3I-201 in obesity-induced extensive mammary hyperplasia ENSG00000087245 ENSG00000168610 PMC8489683__F1 Relieving Cellular Energy Stress in Aging, Neurodegenerative, and Metabolic Diseases, SIRT1 as a Therapeutic and Promising Node ENSG00000134086 ENSG00000105835 ENSG00000150907 ENSG00000106459 PMC4673623__F1 Simplified diagram of one-carbon metabolism (1-CM) including the methionine cycle, the roles of one-carbon nutrients, and links to lipid metabolism ENSG00000173599 ENSG00000133027 PMC7140716__F1 Role of ARTS and Smac in induction of apoptosis ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC7140716__F2 Models for Smac-mimetic (SM) and ARTS-mimetic (AM) mode of action ENSG00000104856 ENSG00000137275 ENSG00000102871 ENSG00000131323 ENSG00000168040 ENSG00000127191 ENSG00000285379 PMC4922058__F4 Illustration of metabolic pathways reported to have altered gene and metabolite expression by integrated pathway analysis (MetaboAnalyst) ENSG00000087253 ENSG00000110721 ENSG00000065833 ENSG00000026652 PMC4354890__F1 Causes and Consequences of Replication Stress ENSG00000175054 ENSG00000164053 ENSG00000132646 ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000166508 PMC2854673__F1 Minimally oxidized LDL induces TLR4-dependent lipoprotein uptake by macrophages ENSG00000070831 ENSG00000170458 ENSG00000163914 ENSG00000136869 ENSG00000141968 PMC8348875__F8 Hinokitiol Exhibits Antitumor Properties through Induction of ROS-Mediated Apoptosis and p53-Driven Cell-Cycle Arrest in Endometrial Cancer Cell Lines (Ishikawa, HEC-1A, KLE) ENSG00000135446 PMC9675355__F5 Regulators of nucleotide excision repair (NER) in melanocytes ENSG00000175054 ENSG00000136160 ENSG00000136936 PMC4676710__F1 A and B, top two networks of proteins eliciting a significantly elevated (P < 0.01; mean ratio > 2) autoimmune response in WHI human prediagnostic TNBC samples, based on Ingenuity Pathway Analysis ENSG00000168036 ENSG00000127948 PMC4676710__F3 And B, top two networks of proteins eliciting a significantly elevated (P < 0.01; mean ratio > 2) response in C3(1)-T TNBC mouse model samples collected before palpable tumor compared with baseline, based on Ingenuity Pathway Analysis ENSG00000001167 ENSG00000109654 ENSG00000116266 PMC4694982__F9 By inhibiting Ras/Raf/ERK and MMP-9, knockdown of EpCAM inhibits breast cancer cell growth and metastasis ENSG00000119888 ENSG00000177606 PMC2670521__F9 New Microbicidal Functions of Tracheal Glands: Defective Anti-Infectious Response to Pseudomonas aeruginosa in Cystic Fibrosis ENSG00000112619 ENSG00000197893 ENSG00000291971 ENSG00000198561 ENSG00000136643 ENSG00000168878 ENSG00000127191 ENSG00000261371 ENSG00000063176 ENSG00000015520 ENSG00000188611 ENSG00000185591 ENSG00000022267 ENSG00000100603 PMC4698256__F1 Proposed cytotoxic mechanisms of NEDDylaton inhibition in human malignancies ENSG00000167513 ENSG00000198793 ENSG00000155792 PMC4896925__F2 Localization of AKAPs in T cells PMC6875203__F3 Cross talk between induction of mitochondrial oxidative/nitrosative stress and autophagy ENSG00000149311 ENSG00000169291 ENSG00000101871 ENSG00000131943 ENSG00000112561 ENSG00000189403 PMC9148418__F6 Pharmacological modulation of healthy aging with urolithin A, NAD+, resveratrol and spermidine ENSG00000096717 ENSG00000142082 ENSG00000106459 PMC7966414__F1 Simplified metabolism of Lupinus albus nodules and cluster roots under P and N deficiencies ENSG00000062485 PMC3730487__F2 Two mechanisms of phase II xenobiotic-metabolizing enzyme induction by phase II inducers ENSG00000178573 ENSG00000106546 ENSG00000106459 PMC8989838__F6 Metabolic Reprogramming of Alloreactive T Cells Through TCR/MYC/mTORC1/E2F6 Signaling in aGvHD Patients ENSG00000136997 ENSG00000152556 PMC3347034__F3 Inhibition of type I IFN signaling by DENV: IFNA/B binds the type I IFN receptor (IFNAR), which is composed of IFNAR1 and IFNAR2 and is found on the surface of nucleated cells ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC3998185__F7 Metastatic Stem Cells: Sources, Niches, and Vital Pathways ENSG00000182578 ENSG00000135547 ENSG00000107562 ENSG00000143546 ENSG00000291971 ENSG00000163739 ENSG00000138798 ENSG00000168610 ENSG00000121966 ENSG00000170365 ENSG00000041982 ENSG00000138755 ENSG00000184371 ENSG00000152952 ENSG00000162692 ENSG00000146648 PMC5436704__F3 Cell–cell communication and cyclic AMP coordinates oocyte meiotic maturation in worms and mammals ENSG00000172572 ENSG00000173406 ENSG00000141968 PMC7993611__F1 Hypopigmented burn hypertrophic scar contains melanocytes that can be signaled to re-pigment by synthetic alpha-melanocyte stimulating hormone in vitro ENSG00000173599 ENSG00000080166 ENSG00000107165 PMC7912475__F2 Impact of Maternal Food Restriction on Heart Proteome in Appropriately Grown and Growth-Restricted Wistar—Rat Offspring ENSG00000105664 ENSG00000130234 ENSG00000115020 ENSG00000138071 ENSG00000171388 ENSG00000133818 ENSG00000155657 PMC7088938__F4 Fusion hallmarks: trends in cellular pathways fusions by fusion event cluster ENSG00000163914 ENSG00000178568 ENSG00000140443 PMC7464402__F8 Apoptosis signalling pathway and cell cycle arrest in response to Moringa extract and 3-HBI ENSG00000002330 ENSG00000006712 PMC12061513__F4 Protein palmitoylation modifications are involved in regulating osteogenic matrix mineralization and differentiation signals ENSG00000107779 ENSG00000170365 ENSG00000206013 ENSG00000134285 ENSG00000204217 PMC4951290__F1 Nuclear-directed human pancreatic ribonuclease (PE5) targets the metabolic phenotype of cancer cells ENSG00000151376 ENSG00000113161 ENSG00000169710 ENSG00000052802 ENSG00000065833 ENSG00000074800 ENSG00000092621 ENSG00000116133 ENSG00000149809 ENSG00000114054 ENSG00000172296 ENSG00000146701 ENSG00000167701 PMC11548906__F2 Regulation of adipogenesis in lipedema ENSG00000182578 ENSG00000129226 ENSG00000137872 ENSG00000102802 ENSG00000122870 ENSG00000102575 ENSG00000143353 ENSG00000104332 ENSG00000166147 ENSG00000283100 ENSG00000132170 ENSG00000245848 ENSG00000170365 ENSG00000172260 ENSG00000260314 ENSG00000172216 ENSG00000132205 ENSG00000184371 ENSG00000107485 ENSG00000128342 ENSG00000096717 ENSG00000179348 ENSG00000178568 ENSG00000087274 PMC10383192__F1 Peptide Vaccine Design Targeting KIT Mutations in Acute Myeloid Leukemia ENSG00000157404 ENSG00000002330 ENSG00000291971 ENSG00000198793 PMC9127082__F1 Ferroptosis: A Critical Moderator in the Life Cycle of Immune Cells ENSG00000161905 ENSG00000151012 ENSG00000167468 ENSG00000102967 PMC7281113__F1 HOTAIR role in breast cancer (BC) drug resistance mechanisms with details of the main molecular pathways involved ENSG00000128710 ENSG00000002330 ENSG00000160182 ENSG00000168036 PMC7281113__F2 Main cellular processes inhibited or activated by the silencing of HOTAIR in BC cells ENSG00000128710 ENSG00000002330 ENSG00000038427 ENSG00000198793 ENSG00000107485 ENSG00000171791 PMC11632373__F1 Biosynthetic pathway of GPI-APs ENSG00000069943 ENSG00000135845 ENSG00000100564 ENSG00000197563 ENSG00000185808 ENSG00000255072 ENSG00000197121 ENSG00000165282 ENSG00000112293 ENSG00000173409 ENSG00000275600 ENSG00000142892 ENSG00000165152 ENSG00000143315 ENSG00000161395 ENSG00000163964 ENSG00000108474 ENSG00000060642 ENSG00000129925 ENSG00000101464 ENSG00000124155 ENSG00000148985 ENSG00000136908 ENSG00000274811 PMC5572180__F3 Alterations to the phosphatidylinositol-3-kinase (PI3K)/Akt signalling pathway and outcome prediction in ovarian clear cell carcinoma (OCCC) ENSG00000105647 ENSG00000121879 PMC7852150__F1 Metabolic features of hPSCs ENSG00000100412 ENSG00000169710 ENSG00000135069 PMC5228426__F2 Most highly-rated network of microRNA-1297 target genes in Ingenuity Pathway Analysis ENSG00000120690 ENSG00000140937 ENSG00000165156 ENSG00000083799 ENSG00000064692 ENSG00000120616 ENSG00000134253 ENSG00000081189 ENSG00000139687 ENSG00000143995 ENSG00000276068 PMC3642326__F7 CQ excites TRPA1 and TRPC3, sensitizes TRPV1, and inhibits TRPM8 through different signaling mechanisms ENSG00000104321 ENSG00000138741 ENSG00000196689 PMC7015249__F9 Serum amyloid A 1 (SAA1) induced muscle atrophy ENSG00000174125 ENSG00000288411 ENSG00000173039 ENSG00000136869 PMC9532536__F8 Cucurbitacin B-induced G2/M cell cycle arrest of conjunctival melanoma cells mediated by GRP78–FOXM1–KIF20A pathway ENSG00000134057 ENSG00000112984 ENSG00000175899 ENSG00000166851 PMC6013765__F3 “threshold model”, as exemplified by the FGF8-FGFR system, can explain disparities in transcriptional activity ENSG00000070610 ENSG00000164778 PMC8558176__F1 WNT3 hypomethylation counteracts low activity of the Wnt signaling pathway in the placenta of preeclampsia ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9534556__F2 Potential of Valeriana as a traditional Chinese medicine: traditional clinical applications, bioactivities, and phytochemistry ENSG00000087085 PMC6602412__F2 M6A on the AKT signaling pathway ENSG00000198793 ENSG00000040199 ENSG00000186654 PMC6602412__F3 M6A on the JAK/STAT signaling pathway ENSG00000115415 ENSG00000105639 ENSG00000168610 PMC8458633__F8 Network Pharmacology and Experimental Validation Reveal the Effects of Chidamide Combined With Aspirin on Acute Myeloid Leukemia-Myelodysplastic Syndrome Cells Through PI3K/AKT Pathway ENSG00000291971 ENSG00000135446 ENSG00000123374 ENSG00000100985 ENSG00000145386 ENSG00000164305 PMC7229175__F7 BIG1 controls macrophage pro-inflammatory responses through ARF3-mediated PI(4,5)P2 synthesis ENSG00000172936 ENSG00000136869 ENSG00000134287 ENSG00000150455 PMC7312764__F6 Analysis of the major constituents in SHED-CM and the plausible mechanisms of SHED-CM-mediated neuroprotective effects ENSG00000112038 ENSG00000174996 ENSG00000185386 ENSG00000105329 ENSG00000115457 ENSG00000167779 ENSG00000143933 ENSG00000154134 PMC7485335__F2 ICOS signaling pathway in Tregs ENSG00000186810 ENSG00000134982 ENSG00000049768 PMC9184479__F6 Central metabolism of C. albicans is altered by L. rhamnosus colonization ENSG00000122966 ENSG00000162551 ENSG00000172005 ENSG00000062485 PMC7827874__F2 Transforming growth factorB (TGFB) superfamily signaling in PAH ENSG00000170365 ENSG00000070831 ENSG00000156574 ENSG00000125968 PMC8093614__F1 PD-1 Immune Checkpoint Inhibitor Therapy Malignant Tumor Based on Monotherapy and Combined Treatment Research ENSG00000134982 PMC7827874__F4 Endothelial to mesenchymal transition (EndoMT) in PAH ENSG00000087245 ENSG00000110799 ENSG00000170558 ENSG00000100985 PMC12245985__F7 Late‐stage DMD skeletal muscle transcriptomic changes in TGFB signalling pathway ENSG00000170365 ENSG00000105329 ENSG00000106483 ENSG00000137766 ENSG00000148848 ENSG00000198947 PMC9052997__F1 An adult case of NOTCH3 mutation in pulmonary artery hypertension ENSG00000168214 ENSG00000074181 PMC10911275__F4 FlyBase Pathway Report pages ENSG00000110395 ENSG00000163914 ENSG00000146648 PMC11667160__F6 The common upstream signaling pathways of autophagy and apoptosis under ERS ENSG00000128272 ENSG00000197930 ENSG00000198793 ENSG00000100219 ENSG00000127191 PMC11667160__F4 Schematic diagram illustrating the macroautophagy process ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC11667160__F5 Schematic diagram of ERS regulating autophagy through four pathways ENSG00000128272 ENSG00000198793 ENSG00000100219 ENSG00000127191 ENSG00000285069 PMC3356354__F10 High-Throughput Sequence Analysis of Turbot (Scophthalmus maximus) Transcriptome Using 454-Pyrosequencing for the Discovery of Antiviral Immune Genes ENSG00000110395 ENSG00000213658 ENSG00000010810 ENSG00000163599 ENSG00000113263 PMC11667160__F3 ERS-induced apoptosis ENSG00000128272 ENSG00000197930 ENSG00000127191 PMC6604479__F2 Improving Outcome in Infantile Autism with Folate Receptor Autoimmunity and Nutritional Derangements: A Self-Controlled Trial ENSG00000139287 ENSG00000035928 PMC1913583__F1 The methionine and folic acid cycles and the metabolic pathway of arsenic ENSG00000214435 PMC3963078__F7 HIV-1 Nef Induces CCL5 production in astrocytes through p38-MAPK and PI3K/Akt pathway and utilizes NF-kB, CEBP and AP-1 transcription factors ENSG00000117020 PMC9356043__F9 Virus-host interaction analysis in colorectal cancer identifies core virus network signature and small molecules ENSG00000123374 ENSG00000124795 ENSG00000067048 ENSG00000215301 PMC8006014__F1 Insulin signaling pathways ENSG00000159224 ENSG00000110395 PMC8006014__F2 Pathological effect and consequence of insulin resistance ENSG00000171105 ENSG00000002330 ENSG00000150907 PMC9259869__F1 Gestational Diabetes Mellitus and Energy-Dense Diet: What Is the Role of the Insulin/IGF Axis? ENSG00000115457 ENSG00000169047 ENSG00000146678 ENSG00000140443 PMC2798710__F1 New roles for Notch in tuberous sclerosis ENSG00000148400 ENSG00000198793 ENSG00000168610 PMC7755949__F3 Ubiquitin System and A20: Implications in Health and Disease ENSG00000102871 ENSG00000157625 ENSG00000083799 ENSG00000175104 ENSG00000127191 PMC7715027__F2 Transcription regulation and consequent tissue functions in hypercapnia ENSG00000145824 ENSG00000107562 ENSG00000162924 ENSG00000171791 ENSG00000143196 PMC11784343__F6 The figure shows the PI-PLC protein, which participates in the IP3 and IP4 synthesis pathways and mobilizes calcium to regulate cell reactions and proliferation requiring free calcium ENSG00000122691 ENSG00000168036 PMC5772763__F1 Aneuploid cell survival relies upon sphingolipid homeostasis ENSG00000198964 ENSG00000164023 ENSG00000148154 PMC8814915__F1 A9-Containing Nicotinic Receptors in Cancer ENSG00000122691 ENSG00000168610 ENSG00000174343 ENSG00000100034 PMC7287924__F1 Model Schematic ENSG00000122966 ENSG00000291971 PMC5125867__F2 T cells in Systemic Lupus Erythematosus ENSG00000198793 ENSG00000137265 ENSG00000026508 ENSG00000168610 PMC6170398__F2 Central role of hepcidin in regulation of iron metabolism ENSG00000178752 ENSG00000168610 PMC7824065__F6 Metabolic reprogramming to form metastatic tumors ENSG00000092621 ENSG00000100033 ENSG00000070669 PMC2922222__F1 Conserved ATR→CHK1 checkpoint signaling pathway in eukaryotes (, ) ENSG00000175054 ENSG00000164053 PMC2517145__F1 PI-3kinase pathway in hematopoietic stem cells and leukemia-initiating cells: a mechanistic difference between normal and cancer stem cells ENSG00000169047 ENSG00000163914 PMC5464836__F9 Combinatorial treatment with polyI:C and anti-IL6 enhances apoptosis and suppresses metastasis of lung cancer cells ENSG00000168610 ENSG00000164342 PMC5684649__F1 Proposed salinity tolerance mechanism in Cicer arietinum L ENSG00000138380 ENSG00000115904 ENSG00000112186 ENSG00000100485 PMC8317254__F1 Mitochondrial and Organellar Crosstalk in Parkinson’s Disease ENSG00000116688 ENSG00000171791 ENSG00000171109 PMC9600485__F1 TRAIL in the Treatment of Cancer: From Soluble Cytokine to Nanosystems ENSG00000120868 ENSG00000168040 PMC5955615__F1 Inhibition of the dysregulated NF-kB/YY1/Snail loop ENSG00000100811 ENSG00000170558 PMC5904225__F10 Schematic summary of the findings ENSG00000108691 ENSG00000125538 ENSG00000169429 PMC7933493__F1 Retinoid cycle of retina ENSG00000121207 ENSG00000116745 ENSG00000197713 PMC8961787__F1 Mitochondrial Metabolism, Redox, and Calcium Homeostasis in Pulmonary Arterial Hypertension ENSG00000151726 ENSG00000135218 ENSG00000120437 ENSG00000103257 ENSG00000075239 PMC9185072__F3 Increased serum concentrations of estrogen-induced growth factors Midkine and FGF2 in NF1 patients with plexiform neurofibroma ENSG00000157554 ENSG00000196712 PMC6454881__F6 NAD+ regulates T-cell differentiation through a novel MC-dependent signaling pathway ENSG00000042832 ENSG00000107485 ENSG00000049768 PMC5368067__F1 Wnt signaling pathway and targets of small‐molecule inhibitors ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167874 ENSG00000168036 PMC10318600__F1 Signaling pathway of ferroptosis ENSG00000167468 PMC9044760__F2 RIPK3-mediated necroptotic pathway ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000026103 PMC7261776__F8 Abnormal expression of bHLH3 disrupts a flavonoid homeostasis network, causing differences in pigment composition among mulberry fruits ENSG00000115419 ENSG00000062485 PMC5004891__F4 STING: infection, inflammation and cancer ENSG00000164430 ENSG00000125538 ENSG00000172936 PMC7071808__F2 Oxidative stress in TGFB1-mediated fibrosis ENSG00000175104 PMC9638655__F1 Blood-based biomarkers for diagnosis, prognosis, and severity prediction of COVID-19: Opportunities and challenges ENSG00000099866 ENSG00000130234 ENSG00000162692 ENSG00000164342 PMC11277296__F2 Mechanisms of mitochondrial dysfunction ENSG00000162711 ENSG00000183735 ENSG00000164430 ENSG00000168958 ENSG00000102871 ENSG00000116688 ENSG00000168040 ENSG00000171109 ENSG00000115317 ENSG00000214253 PMC8468289__F1 Influencing Factors and Molecular Pathogenesis of Sarcopenia and Osteosarcopenia in Chronic Liver Disease ENSG00000177169 ENSG00000122180 ENSG00000118515 ENSG00000155792 ENSG00000129152 PMC3857553__F2 Summary of Tim-3 expression on different innate immune cell populations and its functions ENSG00000239732 ENSG00000166278 ENSG00000164342 PMC3947657__F4 H460 non-small cell lung cancer stem-like holoclones yield tumors with increased vascularity ENSG00000135549 ENSG00000145908 ENSG00000135218 ENSG00000130234 ENSG00000086991 ENSG00000197381 PMC8959827__F8 PDK4 Inhibition Ameliorates Melatonin Therapy by Modulating Cerebral Metabolism and Remyelination in an EAE Demyelinating Mouse Model of Multiple Sclerosis ENSG00000141086 ENSG00000113161 PMC3794709__F1 Steps in the reverse cholesterol transport pathway ENSG00000130164 ENSG00000100979 ENSG00000160179 PMC8949885__F2 Marginal Zone B-Cell Populations and Their Regulatory Potential in the Context of HIV and Other Chronic Inflammatory Conditions ENSG00000174123 ENSG00000119508 ENSG00000186716 ENSG00000198793 ENSG00000112149 PMC3439334__F5 WNT signalling pathway map enriched with genes up-regulated in tumorgraft-forming tumors ENSG00000087095 ENSG00000169291 ENSG00000137673 ENSG00000070831 ENSG00000291971 ENSG00000149269 ENSG00000198793 ENSG00000168036 ENSG00000122194 ENSG00000141968 ENSG00000182541 PMC4338284__F4 Molecular Characterization of the Peripheral Airway Field of Cancerization in Lung Adenocarcinoma ENSG00000110711 ENSG00000147202 ENSG00000120875 ENSG00000066322 ENSG00000073712 ENSG00000169032 ENSG00000173402 ENSG00000114383 ENSG00000101557 PMC3439334__F6 Immune response pathway map enriched with genes down-regulated in the tumorgraft forming patient tumors ENSG00000169291 ENSG00000111537 ENSG00000095015 ENSG00000141968 PMC8580479__F1 Hallmark features of cellular senescence ENSG00000108691 ENSG00000198793 ENSG00000115009 PMC4838829__F4 Genome-wide association studies for fatty acid metabolic traits in five divergent pig populations ENSG00000170522 ENSG00000134824 ENSG00000169710 ENSG00000099194 PMC3337162__F2 Polarization of migrating cortical neurons by Rap1 and N-cadherin ENSG00000017797 ENSG00000070831 ENSG00000140575 ENSG00000006451 ENSG00000144118 ENSG00000160293 PMC11206589__F1 Synergic Role of Dietary Bioactive Compounds in Breast Cancer Chemoprevention and Combination Therapies ENSG00000169710 ENSG00000146648 ENSG00000140443 PMC5649128__F1 Role of Platelet-Derived Transforming Growth FactorB1 and Reactive Oxygen Species in Radiation-Induced Organ Fibrosis ENSG00000175104 PMC5295401__F5 Anti-cancer effects of nitrogen-containing bisphosphonates on human cancer cells ENSG00000285193 ENSG00000168522 PMC7015854__F2 Isolation of an archaeon at the prokaryote–eukaryote interface ENSG00000122966 ENSG00000104808 ENSG00000172005 PMC9956228__F2 New Insights into the Genetics and Epigenetics of Aging Plasticity ENSG00000151376 ENSG00000116539 ENSG00000083168 ENSG00000108799 ENSG00000196591 ENSG00000117139 ENSG00000077463 ENSG00000283100 ENSG00000065833 ENSG00000073614 ENSG00000142611 ENSG00000109685 ENSG00000096717 ENSG00000082212 PMC9417543__F1 Microbiota and COVID-19: Long-term and complex influencing factors ENSG00000130234 ENSG00000198793 ENSG00000184012 ENSG00000118520 ENSG00000049768 PMC4650145__F7 NeurimmiRs were found targeting multiple molecules of the integrin and NFKB pathway ENSG00000005339 ENSG00000197530 ENSG00000070831 ENSG00000080371 ENSG00000131323 ENSG00000127191 ENSG00000106100 ENSG00000108774 ENSG00000010671 PMC5821033__F2 TGFB/SMAD4 signaling in cancer ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC11603854__F1 Current concept of the signaling pathway underlying the Beta-adrenergic regulation of CaV1 ENSG00000080166 ENSG00000062485 PMC4696840__F3 miRNAs regulate cell metabolism by targeting key metabolic enzymes and multiple oncogenic signaling pathways ENSG00000019991 ENSG00000198793 ENSG00000078237 ENSG00000146648 ENSG00000115419 ENSG00000159399 PMC4148364__F5 Pathway analysis using the Kyoto Encyclopedia of Genes and Genomes (KEGG) Pathway database ENSG00000138778 ENSG00000065833 PMC11083429__F1 When a DNA single-strand break (SSB) happens, poly (ADP-ribose) polymerase (PARP) guides SSB repair through NAD+poly(ADP-ribosyl)ation (PARylation) of histones and chromatin remodeling enzymes ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000141867 ENSG00000083093 ENSG00000144554 ENSG00000162607 ENSG00000149554 ENSG00000138385 PMC8061829__F1 Fungal cell wall: An underexploited target for antifungal therapies PMC11206589__F2 Suggested anticancer molecular mechanisms of bromelain ENSG00000135446 ENSG00000026508 ENSG00000123374 PMC11206589__F3 Suggested anticancer molecular mechanisms of sulforaphane ENSG00000135446 ENSG00000125538 ENSG00000026508 ENSG00000123374 ENSG00000105810 PMC3866192__F1 Polymorphisms of CYP51A1 from Cholesterol Synthesis: Associations with Birth Weight and Maternal Lipid Levels and Impact on CYP51 Protein Structure ENSG00000132196 ENSG00000112972 ENSG00000001630 ENSG00000116133 ENSG00000143815 ENSG00000172893 ENSG00000109929 ENSG00000113161 ENSG00000120437 PMC4066667__F3 Current understanding of molecular mechanisms regulating spermatogonial stem cell (SSC) self-renewal in mice ENSG00000141384 ENSG00000244405 ENSG00000010810 ENSG00000138798 PMC9242006__F1 Unconventional Protein Secretion in Brain Tumors Biology: Enlightening the Mechanisms for Tumor Survival and Progression ENSG00000125538 ENSG00000174804 ENSG00000001626 ENSG00000119912 ENSG00000067715 PMC8216287__F4 Multi-functionality of UHRF1: epigenome maintenance and preservation of genome integrity ENSG00000149311 ENSG00000012048 ENSG00000276043 PMC5093979__F3 Genes and interaction relationship in the module 31 (a) and 35 (b) ENSG00000117228 ENSG00000151657 ENSG00000163568 ENSG00000132646 ENSG00000050165 ENSG00000077514 ENSG00000168310 ENSG00000125347 ENSG00000106628 PMC5979412__F3 NFKB-Mediated Inflammation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage. Does Autophagy Play a Role? ENSG00000104856 ENSG00000198793 ENSG00000173039 PMC3852044__F3 MAPK signalling pathway ENSG00000087095 ENSG00000163930 ENSG00000172680 ENSG00000170458 ENSG00000175104 ENSG00000127191 ENSG00000081189 ENSG00000132341 ENSG00000026103 PMC3852044__F4 Wnt signalling pathway ENSG00000087095 ENSG00000134982 ENSG00000113558 ENSG00000196470 PMC12183292__F3 Molecular activity of platelet-regulated T cell immune response in acquired aplastic anemia (AA) ENSG00000186810 ENSG00000111537 PMC11979264__F7 Mechanisms by which Met inhibits HGHF-induced ferroptosis and DOP ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000167996 PMC12136294__F4 Profiles of DEGs and DAMs in TCA cycle, insulin signaling pathway and Glycerophospholipid metabolism in response to diapause ENSG00000173599 ENSG00000105953 ENSG00000062485 PMC2896553__F6 DISTINCT SPECTRUM OF COPY NUMBER ABERRATIONS IN PAEDIATRIC HIGH GRADE GLIOMAS ENSG00000149311 ENSG00000065526 ENSG00000167653 PMC8959898__F1 Non-Alcoholic Fatty Liver Disease in HIV/HBV Patients – a Metabolic Imbalance Aggravated by Antiretroviral Therapy and Perpetuated by the Hepatokine/Adipokine Axis Breakdown ENSG00000136457 ENSG00000170458 ENSG00000105550 ENSG00000198793 ENSG00000136869 PMC4365363__F3 The major TNFR1-mediated signaling pathways ENSG00000102871 ENSG00000157625 ENSG00000168040 ENSG00000168404 ENSG00000127191 PMC7556656__F1 NOTCH1 signaling pathway and effects of NOTCH1 mutations on CLL susceptibility to anti-CD20 mAb ENSG00000065526 ENSG00000148400 ENSG00000134982 ENSG00000137845 PMC6255977__F1 Transcriptome response of Salvia miltiorrhiza to overexpression of AtPAP1 ENSG00000121807 ENSG00000062485 ENSG00000084774 PMC6885903__F3 The constructed network included a main connected component and 9 isolated nodes (DEGs) ENSG00000155307 ENSG00000134321 ENSG00000187608 ENSG00000089127 ENSG00000115415 ENSG00000081237 ENSG00000140968 ENSG00000157601 ENSG00000135114 ENSG00000185745 PMC10124776__F1 Pig heart and lung xenotransplantation: Present status ENSG00000069482 ENSG00000198053 ENSG00000134982 PMC6797571__F2 Platelet‐derived growth factors from breast cancer or neuroblastoma stimulate the platelet‐derived growth factor (PDGF) receptors and initiate immune and tumorigenesis response ENSG00000100290 ENSG00000239732 ENSG00000002330 ENSG00000081154 ENSG00000136869 ENSG00000164342 PMC4287412__F9 Regulation of Wnt canonical and calcium-dependent pathway molecules in microstructured Ti surfaces ENSG00000154342 ENSG00000169071 ENSG00000134982 ENSG00000167941 ENSG00000155011 ENSG00000104332 PMC7356262__F11 Schematic figure of the NFKB signaling pathway and inhibition of IKK complex after treatment with VA ENSG00000102871 ENSG00000125538 ENSG00000172936 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC4957332__F4 Changes in transcript abundance of genes involved in central metabolic pathways and bioprocesses in response to elevated CO2 in C-169 ENSG00000036473 ENSG00000062485 PMC6851586__F1 Pathways in the pathogenesis of PSO ENSG00000169248 ENSG00000284881 ENSG00000081041 ENSG00000163739 ENSG00000285433 ENSG00000143556 ENSG00000168610 ENSG00000169245 ENSG00000285176 ENSG00000138755 ENSG00000125538 ENSG00000163734 ENSG00000169429 ENSG00000115009 ENSG00000186832 PMC11873641__F1 Metabolic adaptations in cancer cells ENSG00000131473 ENSG00000135218 ENSG00000130164 ENSG00000134824 ENSG00000099194 ENSG00000026103 PMC7600801__F1 MAPK signaling pathway (A) in a BRAF inhibitor-sensitive cell showing sites of action of BRAF inhibitors and MEK inhibitors, and (B) after BRAF inhibitor resistance development ENSG00000157764 ENSG00000198793 ENSG00000196712 PMC11873641__F4 Intricate signaling pathways linking obesity to cancer progression ENSG00000198793 ENSG00000136997 ENSG00000140443 PMC5627415__F2 Epigenetic mechanisms currently associated with aortic VICs ENSG00000170365 ENSG00000087245 ENSG00000156103 ENSG00000105329 ENSG00000242252 ENSG00000118785 ENSG00000157227 ENSG00000162551 ENSG00000168036 ENSG00000100985 ENSG00000077463 PMC9444135__F1 Purinergic receptors are a key bottleneck in tumor metabolic reprogramming: The prime suspect in cancer therapeutic resistance ENSG00000198793 ENSG00000162692 PMC8399842__F1 Nanoparticulate Drug Delivery Strategies to Address Intestinal Cytochrome P450 CYP3A4 Metabolism towards Personalized Medicine ENSG00000168610 ENSG00000007171 PMC2975200__F9 MyD88-induced protein accumulation pathways through SQSTM1 and HDAC6 ENSG00000094631 ENSG00000284099 ENSG00000172936 ENSG00000083799 ENSG00000175104 PMC3193496__F1 Two conserved branches of the canonical Wnt pathway ENSG00000071564 ENSG00000204070 ENSG00000064393 PMC3229036__F2 Subversion of the actin cytoskeleton during viral infection ENSG00000106683 ENSG00000070831 ENSG00000291971 ENSG00000067900 ENSG00000088926 ENSG00000182541 PMC3193496__F2 HIPK2 and NLK/LIT-1 in Wnt signaling ENSG00000071564 ENSG00000087095 ENSG00000064393 ENSG00000277641 ENSG00000196628 ENSG00000125084 PMC4610178__F4A Invasive Bladder Cancer: Genomic Insights and Therapeutic Promise ENSG00000112242 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000139687 ENSG00000124762 PMC9321669__F5 Dissimilative Pathway of Komagataella phaffii (Pichia pastoris): Formaldehyde Toxicity and Energy Metabolism ENSG00000142192 ENSG00000141086 ENSG00000172005 PMC7885873__F1 Cytokine regulated alterations to the splenic microenvironment during experimental visceral leishmaniasis ENSG00000107562 ENSG00000089692 ENSG00000137077 ENSG00000126353 PMC7675396__F4 Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation ENSG00000003436 ENSG00000130234 ENSG00000125538 PMC5325762__F4 The DNA Damage Response During the Life Cycle of Human Papillomaviruses ENSG00000175054 ENSG00000164053 ENSG00000276618 PMC6391454__F4 Graphic image representation of the possible mechanisms of lung inflammation in COPD involving purinergic signaling pathway ENSG00000196839 ENSG00000197594 ENSG00000054179 ENSG00000138185 ENSG00000168032 PMC8508793__F2 RNA Deregulation in Amyotrophic Lateral Sclerosis: The Noncoding Perspective ENSG00000204842 ENSG00000148798 ENSG00000123609 ENSG00000284770 PMC5325762__F3 The DNA Damage Response During the Life Cycle of Human Papillomaviruses ENSG00000149311 ENSG00000012048 ENSG00000163961 PMC4304915__F6 HIV-1 Tat activates a RhoA signaling pathway to reduce NMDA-evoked calcium responses in hippocampal neurons via an actin-dependent mechanism ENSG00000291971 ENSG00000180104 PMC4706528__F1 PI3K/Akt/mTOR (PAM) pathway and inhibitors of the pathway tested in phase I-III clinical trials on solid tumors and/or breast cancer ENSG00000109452 ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC4491894__F3 Differential expression of a core set of genes whose products comprise a functional interactome is an underlying feature of chronically wounded RPE cells ENSG00000145681 ENSG00000076003 ENSG00000166147 ENSG00000178445 ENSG00000162607 ENSG00000022267 ENSG00000118257 ENSG00000155760 ENSG00000101333 ENSG00000135919 ENSG00000138346 ENSG00000117228 ENSG00000092853 ENSG00000163453 ENSG00000187741 ENSG00000148848 ENSG00000183395 ENSG00000274247 ENSG00000069482 ENSG00000118785 ENSG00000197959 ENSG00000109805 ENSG00000111684 ENSG00000111331 ENSG00000151617 ENSG00000049323 ENSG00000165480 ENSG00000105329 ENSG00000124107 ENSG00000104332 ENSG00000112715 ENSG00000160613 ENSG00000118971 ENSG00000137801 ENSG00000072571 ENSG00000119514 ENSG00000049130 ENSG00000186340 ENSG00000178573 ENSG00000274334 ENSG00000129946 ENSG00000166501 ENSG00000136153 ENSG00000122862 ENSG00000115163 ENSG00000113140 ENSG00000134363 ENSG00000153208 ENSG00000185386 ENSG00000197299 PMC9612213__F3 Molecular Mechanisms of Inflammasome in Ischemic Stroke Pathogenesis ENSG00000162711 ENSG00000137275 ENSG00000172936 ENSG00000136869 ENSG00000168040 PMC6300500__F1 Models for antigen cross-presentation mechanisms induced by adjuvants in DCs ENSG00000109113 ENSG00000172936 ENSG00000136869 PMC33333__F2 Role of the antioxidant response element and the transcription factor Nrf2 in chemoprevention ENSG00000178573 ENSG00000106459 ENSG00000079999 PMC7332907__F2 Roles of FFA2 in immune cell populations ENSG00000162711 ENSG00000128918 ENSG00000137265 ENSG00000105656 ENSG00000100219 ENSG00000168610 PMC3221684__F8 Insulin Receptor-Mediated Signaling via Phospholipase CG Regulates Growth and Differentiation in Drosophila ENSG00000169291 ENSG00000163914 ENSG00000146648 PMC4009148__F2 Signaling pathways induced by IL-17F ENSG00000175104 ENSG00000163702 PMC9532630__F1 Cellular loci involved in the development of brain arteriovenous malformations ENSG00000157764 ENSG00000163217 PMC3783562__F3 Metabolic actions of Rho-kinase in periphery and brain ENSG00000150907 ENSG00000198793 ENSG00000115138 ENSG00000067900 ENSG00000168610 PMC6812177__F1 Proposed mechanisms of inflammasome involvement in RTT OxInflammation.The scheme summarizes the basal and LPS + ATP-stimulated status of the inflammasome pathway by comparing the responses of CTR and RTT fibroblasts ENSG00000162711 ENSG00000125538 PMC7738752__F1 Omega 3 and Omega 6 metabolic pathway (from ) ENSG00000134824 ENSG00000196839 ENSG00000149485 PMC5397677__F1 Signaling pathways relevant to glial neoplasms in adults and children ENSG00000157764 ENSG00000164362 ENSG00000170430 ENSG00000134853 ENSG00000121879 ENSG00000077782 ENSG00000146648 ENSG00000196712 PMC10038327__F3 Mitochondria as disease-relevant organelles in rheumatoid arthritis ENSG00000150782 ENSG00000148942 ENSG00000125538 PMC140665__F8 Interaction between the Wnt/Beta-catenin and Wnt/Ca2+ pathways ENSG00000087095 ENSG00000168036 ENSG00000125084 PMC10038327__F4 Mitochondria as disease-relevant organelles in rheumatoid arthritis ENSG00000143390 ENSG00000275385 ENSG00000168610 ENSG00000141526 PMC7591300__F1 Phytopharmaceuticals mediated Furin and TMPRSS2 receptor blocking: can it be a potential therapeutic option for Covid-19? ENSG00000140564 ENSG00000130234 ENSG00000184012 PMC11745087__F3 Newly elucidated regulatory mechanisms relevant to RNA m6A modification (created in Figdraw) ENSG00000143799 ENSG00000198793 ENSG00000088247 ENSG00000073792 ENSG00000103257 ENSG00000110801 ENSG00000099381 ENSG00000165819 ENSG00000102974 ENSG00000136231 PMC3193496__F4 Context-dependent function of HIPK2 in Wnt signaling ENSG00000071564 ENSG00000138795 ENSG00000064393 PMC11745087__F2 Outline of the interplay between m6A modification and radiation-induced injury effects on distinct normal organ tissues (created in Figdraw) ENSG00000145388 ENSG00000198492 ENSG00000150907 ENSG00000073792 ENSG00000189403 ENSG00000091542 ENSG00000150455 ENSG00000165819 PMC7488244__F1 Melatonin and urological cancers: a new therapeutic approach ENSG00000168040 ENSG00000096717 PMC3458271__F2 Two proposed models of ephrin-B reverse signaling in palatal EMT based on current evidence ENSG00000198793 ENSG00000168610 PMC11881903__F7 Proposed model depicting the process underlying TOD-dependent muscle regeneration ENSG00000143799 ENSG00000108691 PMC11931045__F2 Red rectangles for upregulation, the blue rectangle for downregulation ENSG00000198793 PMC12024679__F2 Notch1 pathway ENSG00000188290 ENSG00000148400 ENSG00000136997 ENSG00000135144 ENSG00000109670 PMC3712714__F1 Interaction between the vitamin D endocrine system and the inflammatory signaling pathway in control of cancer cell growth (for details, see ) ENSG00000111012 ENSG00000019186 PMC5504949__F2 IL-6/soluble IL-6 receptor signaling at the nexus of endocrine function: illustrative examples ENSG00000159167 ENSG00000115415 ENSG00000168610 ENSG00000277401 PMC5665664__F6 Regulatory model of ATX expression in adipose tissue and the biological functions of adipocyte-derived ATX in diet-induced obesity ENSG00000198670 ENSG00000128342 ENSG00000168610 PMC9415106__F4 Application of Mesoporous Silica Nanoparticles in Cancer Therapy and Delivery of Repurposed Anthelmintics for Cancer Therapy ENSG00000135446 ENSG00000198793 ENSG00000168036 ENSG00000168610 ENSG00000146648 PMC5350572__F8 Illustration shows the proposed overall mechanism by which butyrate inhibited proliferation and induced apoptosis in hepatic cells ENSG00000168036 ENSG00000096717 PMC9452304__F1 Complete biosynthetic pathway for the production of vinblastine in yeast ENSG00000067064 ENSG00000172955 ENSG00000197429 PMC9495847__F10 Paeonol Attenuates Hepatic Ischemia/Reperfusion Injury by Modulating the Nrf2/HO-1 and TLR4/MYD88/NFKB Signaling Pathways ENSG00000172936 ENSG00000136869 ENSG00000079999 PMC6391560__F6 Model for light input to the circadian clock network of Drosophila ENSG00000258429 PMC8458276__F6 Different MMR excision-resynthesis pathways ENSG00000132646 ENSG00000177084 PMC6532024__F6 Regulatory mechanisms of the IL-17–TRAF6 pathway ENSG00000141527 ENSG00000183735 ENSG00000082512 ENSG00000157625 ENSG00000131323 ENSG00000083799 ENSG00000155313 ENSG00000175104 ENSG00000127191 ENSG00000076604 PMC11943269__F4 Schematic model represents the possible RT role in adjuvant therapy for TNBC ENSG00000198793 ENSG00000106853 ENSG00000168610 ENSG00000146648 ENSG00000102967 ENSG00000112742 PMC8017943__F4 GA biosynthesis and isoprenoid pathway mRNAs in SRB suspensor and embryo proper regions PMC3285038__F1 Schematic of Smads mediated TGFB signaling pathway PMC6532024__F2 Receptor signaling pathways upstream of TRAF6 ENSG00000141527 ENSG00000088888 ENSG00000167207 ENSG00000107201 ENSG00000130159 ENSG00000175104 ENSG00000184216 ENSG00000154114 ENSG00000198286 PMC3285038__F2 Schematic summarizing the role of signaling Smads in epithelial carcinogenesis ENSG00000019991 PMC6532024__F3 Inflammatory loops in the EIME of psoriasis ENSG00000141527 ENSG00000288411 ENSG00000081041 ENSG00000163739 ENSG00000175104 ENSG00000162892 ENSG00000115009 PMC6886017__F6 Diagrammatic representations of putative mechanisms of microRNA 375 in regulating metadherin-induced cell proliferation, cell migration, and angiogenesis in human colorectal cancer ENSG00000124102 ENSG00000147649 ENSG00000157764 ENSG00000100906 ENSG00000109320 ENSG00000173039 ENSG00000168036 ENSG00000112715 PMC9532630__F4 Cellular loci involved in the development of brain arteriovenous malformations ENSG00000172936 ENSG00000136869 ENSG00000184216 PMC9294167__F1 Multifaceted Role of STAT3 in NK-Cell Tumor Surveillance ENSG00000105397 ENSG00000168610 PMC6136085__F2 Persistent infections through defective viral genome immunostimulation ENSG00000088888 ENSG00000056558 PMC4294505__F9 CCR7-stimulated phosphorylation-inhibition of AMPK ENSG00000137077 ENSG00000126353 PMC5825917__F3 Means to enhance the immune response in the tumor microenvironment (TME) ENSG00000019991 ENSG00000111537 ENSG00000078098 PMC12127168__F4 Research progress on the therapeutic effects of effective components of traditional Chinese medicine in the treatment of gastric cancer precursors through modulation of multiple signaling pathways ENSG00000033327 ENSG00000002330 PMC12127168__F5 Research progress on the therapeutic effects of effective components of traditional Chinese medicine in the treatment of gastric cancer precursors through modulation of multiple signaling pathways ENSG00000164161 ENSG00000164690 ENSG00000128602 PMC8049868__F1 Recognized pathways of androgen biosynthesis in prostate cancer ENSG00000151632 PMC12127168__F2 Research progress on the therapeutic effects of effective components of traditional Chinese medicine in the treatment of gastric cancer precursors through modulation of multiple signaling pathways ENSG00000172936 ENSG00000175104 ENSG00000127191 PMC4023177__F3 Key signaling pathways involved in the early recurrence/metastasis (R/M≤6months) and late recurrence/metastasis (R/M6-12months) of H-HCC ENSG00000284774 ENSG00000169710 ENSG00000120885 ENSG00000092067 ENSG00000139687 ENSG00000057252 ENSG00000113889 ENSG00000142192 ENSG00000197635 ENSG00000114416 ENSG00000196954 ENSG00000221869 ENSG00000157017 ENSG00000288461 ENSG00000132693 ENSG00000112293 ENSG00000133110 ENSG00000154188 ENSG00000170909 ENSG00000291971 ENSG00000164251 ENSG00000205302 ENSG00000087085 ENSG00000197451 ENSG00000197256 ENSG00000204152 ENSG00000102879 ENSG00000130164 ENSG00000109861 ENSG00000173548 ENSG00000170266 ENSG00000176046 ENSG00000158874 ENSG00000118898 ENSG00000124664 ENSG00000171560 ENSG00000165471 ENSG00000130204 ENSG00000169896 ENSG00000135100 ENSG00000173039 ENSG00000277804 ENSG00000168610 ENSG00000135587 ENSG00000111537 ENSG00000134853 ENSG00000005381 ENSG00000198911 ENSG00000137055 ENSG00000138385 ENSG00000090659 PMC12127168__F3 Research progress on the therapeutic effects of effective components of traditional Chinese medicine in the treatment of gastric cancer precursors through modulation of multiple signaling pathways ENSG00000134982 ENSG00000183579 ENSG00000168036 PMC12127168__F8 Research progress on the therapeutic effects of effective components of traditional Chinese medicine in the treatment of gastric cancer precursors through modulation of multiple signaling pathways ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC4327859__F1 TLR4/NFKB signalling pathway and TLR4/ MAPK signalling pathway in gastrointestinal epithelium ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC9469633__F8 Exosomal Wnt7a from a low metastatic subclone promotes lung metastasis of a highly metastatic subclone in the murine 4t1 breast cancer ENSG00000154764 ENSG00000198793 ENSG00000168036 PMC12127168__F6 Research progress on the therapeutic effects of effective components of traditional Chinese medicine in the treatment of gastric cancer precursors through modulation of multiple signaling pathways ENSG00000105397 PMC4968087__F7 ACTIVATION OF p53 IN DOWN SYNDROME AND IN THE Ts65Dn MOUSE BRAIN IS ASSOCIATED WITH A PRO-APOPTOTIC PHENOTYPE ENSG00000143799 ENSG00000096717 ENSG00000283100 PMC3902845__F2 Multiple changes in gene expression influence KRAS activity, the KRAS downstream pathway and cell growth occur during development of a “mature” PDAC cell ENSG00000163235 ENSG00000138798 ENSG00000146648 PMC3969038__F1 NFKB signaling pathway and cancer related mutations ENSG00000173039 ENSG00000172936 ENSG00000198286 PMC2064840__F9 Divergent TGFB signaling pathways induce transcriptional regulation through Smads and translational regulation through the mTORC1 pathway PMC12019327__F7 Mechanism of anticancer action of salinomycin and oxaliplatin cotreatment against CRC cells ENSG00000132906 ENSG00000164305 PMC5462861__F1 Nrf2 activation by misfolded proteins ENSG00000079999 PMC12021879__F1 Mechanistic map of metabolic bone disease: The pathogenesis of MBD primarily involves four key pathological dimensions: abnormal bone resorption, abnormal bone formation, abnormal mineral deposition, and metabolic factors ENSG00000118972 ENSG00000152266 ENSG00000170365 ENSG00000281324 ENSG00000162337 ENSG00000131196 PMC10451275__F3 Changes in subcellular localization of Ras upon S-nitrosylation ENSG00000291971 PMC5400663__F1 Metabotropic glutamate receptors as a new therapeutic target for malignant gliomas ENSG00000170365 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC7699726__F2 KEAP1-NRF2 modulation in cancers such as RCCs ENSG00000134086 ENSG00000157764 ENSG00000010810 ENSG00000198793 ENSG00000136997 ENSG00000096717 ENSG00000079999 PMC2902148__F2 Inhibition of VEGF signaling pathways ENSG00000112715 ENSG00000150630 PMC2902148__F1 VEGF signaling interactions ENSG00000112715 ENSG00000118257 ENSG00000150630 PMC4255606__F4 Proposed role of stem-progenitor cells in leiomyoma pathogenesis ENSG00000184634 ENSG00000168036 PMC8463536__F3 P53 family members, such as p53, p63, and p73, some transcription factors, such as SP1 and CREB, and noncoding miRNAs, such as miR-144, miR-885-5p, and miR-101 regulate the transcription of TIGAR ENSG00000109685 ENSG00000136997 ENSG00000185591 ENSG00000078237 PMC3422654__F1 Genes Associated with Outcomes in the Context of Two Fatty Acid Metabolism Pathways ENSG00000151726 ENSG00000103150 ENSG00000160216 ENSG00000123983 PMC8463536__F4 Enzymatic activity of TIGAR ENSG00000078237 PMC9220138__F4 Nrf2 Activation in Chronic Kidney Disease: Promises and Pitfalls ENSG00000157184 ENSG00000131473 ENSG00000186575 ENSG00000135218 ENSG00000169710 PMC5984538__F4 NFKB and Wnt signaling pathways ENSG00000023445 ENSG00000087095 ENSG00000105327 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000102871 ENSG00000168036 ENSG00000127191 ENSG00000149311 ENSG00000226275 ENSG00000082512 ENSG00000125538 ENSG00000157625 ENSG00000131323 ENSG00000168646 PMC5864212__F6 Deciphering the nature of the coral–Chromera association ENSG00000102189 ENSG00000135404 PMC10453069__F4 DNA repair pathways of DNA double-strand breaks ENSG00000143799 ENSG00000083093 ENSG00000187741 ENSG00000158169 ENSG00000139618 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000101773 ENSG00000144554 ENSG00000104320 ENSG00000165392 ENSG00000197299 ENSG00000051180 PMC6925091__F5 Necroptosis is an example of antagonistic pleiotropy ENSG00000124256 ENSG00000137275 ENSG00000198793 ENSG00000168404 ENSG00000285379 PMC6558469__F1 Mechanisms of tumor progression and tumor microenvironment‐mediated immune evasion in classic Hodgkin lymphoma (cHL) ENSG00000177575 PMC10453069__F2 ATM- and ATR-mediated pathways in the presence of damaged DNA ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000078900 PMC10453069__F3 Excision repair pathways of DNA single-strand breaks ENSG00000012061 ENSG00000105486 ENSG00000113318 ENSG00000132646 ENSG00000038002 ENSG00000095002 ENSG00000122512 PMC8122702__F2 NRF2/KEAP1 Signaling Pathway in Cancer Metabolism ENSG00000100387 ENSG00000079999 PMC10453069__F1 Clonal evolution of plasma cell dyscrasias ENSG00000149311 ENSG00000157764 ENSG00000136997 PMC9189267__F3 Cell deaths: Involvement in the pathogenesis and intervention therapy of COVID-19 ENSG00000278718 ENSG00000162711 ENSG00000088888 ENSG00000163568 ENSG00000189403 ENSG00000115594 PMC4763179__F1 Living biointerfaces based on non-pathogenic bacteria support stem cell differentiation ENSG00000170365 ENSG00000123552 ENSG00000204217 PMC3379801__F8 p16-Cdk4-Rb signaling pathway diagram ENSG00000135446 ENSG00000105810 PMC6220384__F1 HMBG1 and inflammatory and immune processes ENSG00000107562 ENSG00000189403 ENSG00000136869 ENSG00000168610 ENSG00000121966 PMC4012967__F1 IL-6/JAK/STAT pathway ENSG00000291971 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC4294374__F1 Wnt signaling, de novo lipogenesis, adipogenesis and ectopic fat ENSG00000281324 ENSG00000130164 ENSG00000042832 ENSG00000198793 ENSG00000169174 PMC6220384__F2 HMGB1 and Fas/FasL signal pathway in uveitis ENSG00000189403 ENSG00000162692 ENSG00000026103 PMC2731131__F10 Schematic summary of LPS-triggered programmed cell death in human endothelial cells ENSG00000172936 ENSG00000136869 ENSG00000168040 PMC4285107__F1 New chemical probes targeting cholesterylation of Sonic Hedgehog in human cells and zebrafish ENSG00000164690 PMC4107064__F1 Progress in Central Nervous System Lymphomas ENSG00000107562 ENSG00000186716 ENSG00000136997 ENSG00000137193 ENSG00000113520 ENSG00000172936 ENSG00000136869 ENSG00000171791 ENSG00000168610 ENSG00000184216 ENSG00000010671 PMC8518013__F7 Hedgehog/GLI1 signaling pathway regulates the resistance to cisplatin in human osteosarcoma ENSG00000128602 PMC6530347__F2 Overview of thyroid hormone (TH) production, transport, activity and regulation PMC11380518__F3 Biosynthesis of the IPP and DMAPP via the MVA pathway (purple) and MEP pathway (green) ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC8642962__F6 Novel mutation of SATB2 inhibits odontogenesis of human dental pulp stem cells through Wnt/Beta-catenin signaling pathway ENSG00000168036 PMC3959773__F1 Mitochondrial respiratory chain ENSG00000132423 ENSG00000157184 ENSG00000119723 ENSG00000171503 ENSG00000088682 ENSG00000148459 ENSG00000173085 PMC12193433__F4 IL-6/JAK/STAT3 signaling pathway and oleocanthal-mediated inhibition ENSG00000087245 ENSG00000168610 PMC2624576__F1 Alternative splicing in the NFKB signaling pathway ENSG00000102871 ENSG00000134070 ENSG00000172936 ENSG00000083799 ENSG00000150455 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC12193433__F3 Schematic on HGF/C-Met signaling in mesenchymal cells, activating RAS-ERK, RAC1-JNK, PI3K-AKT, and STAT3 pathways to regulate cellular processes ENSG00000019991 ENSG00000169291 ENSG00000198793 ENSG00000168610 PMC5946030__F2 Mitochondrial DNA mediates pro-inflammatory response ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000105612 ENSG00000172936 PMC2999098__F3 CKI members in canonical Wnt signaling ENSG00000071564 ENSG00000134982 ENSG00000177606 PMC2765788__F6 STRIATAL NEUROPROTECTION WITH METHYLENE BLUE ENSG00000256762 ENSG00000198125 PMC4327859__F4 Post-transcriptional gene suppression mediated by miRNAs is involved in the fine-tuning of epithelial anti-Cryptosporidium defence ENSG00000136869 PMC4041145__F1 Akt and NFKB signaling in drug resistance mechanism of tumor cells ENSG00000002330 PMC7105577__F2 Crosstalk between major signaling pathways during nephron progenitor cell (NPC) differentiation ENSG00000134982 ENSG00000168036 ENSG00000150457 ENSG00000104332 ENSG00000168646 ENSG00000131023 PMC6854009__F4 Highlighted NF-Kappa B Signaling KEGG Pathway (hsa04040) with Enriched Genes from the LRT Analysis (Bonferroni-adjusted p < 0.05) for Influenza Infected Subjects (–) ENSG00000242689 ENSG00000135960 ENSG00000138798 ENSG00000186716 ENSG00000105656 ENSG00000083799 PMC8466445__F1 Anti-Viral Pattern Recognition Receptors as Therapeutic Targets ENSG00000276561 ENSG00000010671 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000133116 ENSG00000134070 ENSG00000131323 ENSG00000198125 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC3413411__F1 PI3K-AKT-mTOR signaling pathway ENSG00000124102 ENSG00000169047 ENSG00000198793 ENSG00000118515 ENSG00000155792 ENSG00000167965 PMC6854009__F5 Highlighted NF-Kappa B Signaling KEGG Pathway (hsa04040) with Enriched Genes from the LRT Analysis (Bonferroni-adjusted p < 0.05) for Influenza Vaccinated Subjects (–) ENSG00000242689 ENSG00000135960 ENSG00000138798 ENSG00000186716 ENSG00000173599 ENSG00000105656 ENSG00000083799 PMC7642822__F8 Regulator effect networks generated by Ingenuity Pathway Analysis (IPA) in MCF7 over-expressed mitochondrial fission factor (MFF) ENSG00000100906 ENSG00000150093 ENSG00000169710 ENSG00000120885 ENSG00000169032 ENSG00000145386 ENSG00000171345 ENSG00000197702 ENSG00000089159 ENSG00000170458 ENSG00000132383 ENSG00000139687 ENSG00000087274 PMC3652384__F2 The mechanism of late PC ENSG00000115415 ENSG00000291971 ENSG00000168610 PMC11852910__F4 Targeting the PARylation-Dependent Ubiquitination Signaling Pathway for Cancer Therapies ENSG00000143799 ENSG00000126016 ENSG00000088888 ENSG00000125398 ENSG00000166164 PMC7160658__F1 Checkpoint inhibition‐induced adverse events ENSG00000134982 PMC11852910__F5 Targeting the PARylation-Dependent Ubiquitination Signaling Pathway for Cancer Therapies ENSG00000143799 ENSG00000118518 ENSG00000107854 PMC5657403__F1 Regulation of the intrinsic pathway to apoptosis by B‐cell‐lymphoma‐2 (BCL2) family members ENSG00000100290 ENSG00000002330 ENSG00000171791 ENSG00000135116 ENSG00000104081 PMC5344425__F1 Nonalcoholic steatohepatitis-related hepatocellular carcinoma: is there a role for the androgen receptor pathway? ENSG00000180210 ENSG00000168036 PMC4075482__F5 Pathway Analysis ENSG00000128609 ENSG00000105953 ENSG00000112992 PMC2655983__F3 Simplified version of colorectal-cancer biological pathway in KEGG database for genes with mutation data in COSMIC ENSG00000124102 ENSG00000157764 ENSG00000134982 ENSG00000168036 PMC7726150__F6 How Lrp6-APEX2 may interact with the ESCRT machinery and TFG in multivesicular body formation during Wnt-induced endocytosis ENSG00000281324 ENSG00000164751 PMC4563120__F5 The acute phase response is not generally up regulated in patients with < 14 mo survival ENSG00000102871 ENSG00000198793 ENSG00000177606 ENSG00000105697 ENSG00000130159 ENSG00000127191 ENSG00000135116 ENSG00000168610 ENSG00000171560 PMC7400809__F4 Action of TET inhibitors ENSG00000138336 ENSG00000185591 ENSG00000168610 ENSG00000143995 PMC10741130__F6 Oleocanthal, an Antioxidant Phenolic Compound in Extra Virgin Olive Oil (EVOO): A Comprehensive Systematic Review of Its Potential in Inflammation and Cancer ENSG00000132906 ENSG00000019991 ENSG00000002330 PMC7866084__F1 NLRP3 inflammasome activation in AD and PD with potential intervention of natural extractions ENSG00000162711 ENSG00000135218 ENSG00000010810 ENSG00000172936 ENSG00000136869 PMC8456397__F2 Molecular Insights into the Crosstalk Between Immune Inflammation Nexus and SARS-CoV-2 Virus ENSG00000213928 ENSG00000105397 ENSG00000164342 PMC8891531__F1 Trained Immunity: An Overview and the Impact on COVID-19 ENSG00000167207 ENSG00000125538 ENSG00000198793 ENSG00000170653 ENSG00000136869 PMC3705551__F2 Major catabolic and anabolic pathways in mammalian cells ENSG00000122966 ENSG00000172005 ENSG00000100170 ENSG00000062485 PMC11242417__F3 Signaling pathways of macrophage polarization ENSG00000138378 ENSG00000105397 ENSG00000148400 ENSG00000115415 ENSG00000136869 ENSG00000118520 ENSG00000105639 ENSG00000175104 ENSG00000168610 PMC9553197__F2 Pharmacological effects and mechanisms of bee venom and its main components: Recent progress and perspective ENSG00000132906 ENSG00000087245 ENSG00000198793 ENSG00000100985 ENSG00000146648 ENSG00000164305 ENSG00000026103 PMC11242417__F1 Macrophage origins and biological functions ENSG00000186716 ENSG00000118520 PMC8222483__F2 Linkage between inflammation and fibrosis in muscular dystrophies: The axis autotaxin–lysophosphatidic acid as a new therapeutic target? ENSG00000291971 ENSG00000163914 ENSG00000198670 PMC5700507__F2 Immediate immune responses of pulmonary resident cells to RSV infection in neonates ENSG00000137033 ENSG00000163739 ENSG00000145777 PMC7785737__F3 Wnt signaling pathways ENSG00000281324 ENSG00000134982 ENSG00000168036 PMC3193874__F2 Caloric Restriction and Chronic Inflammatory Diseases ENSG00000169047 ENSG00000140443 PMC6916499__F1 Retinoid transport and transformations in vision ENSG00000135437 ENSG00000121207 ENSG00000116745 PMC7856191__F8 Galectin-9 bridges human B cells to vascular endothelium while programming regulatory pathways. ENSG00000169291 ENSG00000186716 ENSG00000026751 ENSG00000166278 PMC6434111__F1 l-Arginine de novo synthesis pathways ENSG00000122966 ENSG00000036473 PMC3103318__F7 Model pathway for genistein-induced ASAH1 transcription in MCF-7 cells ENSG00000103222 ENSG00000185591 ENSG00000118777 PMC3693188__F1 TP53-centered network in CLL: A novel pathogenetic model for chronic lymphocytic leukemia (CLL) showing a pathway of microRNAs and cytogenics that are involved in the development of CLL ENSG00000149311 ENSG00000291603 ENSG00000171791 PMC3484676__F3 Rbf1 occupies multiple nodes in conserved signaling pathways ENSG00000132471 ENSG00000142192 ENSG00000140564 ENSG00000069869 ENSG00000175193 ENSG00000065526 ENSG00000170145 ENSG00000101752 PMC2253531__F5 Induction of immune response to Wolbachia infection in S2 cells ENSG00000166402 ENSG00000172936 ENSG00000162924 ENSG00000168040 PMC4751644__F1 PI3K signaling and common mutations related with ASD and schizophrenia ENSG00000102081 ENSG00000155792 ENSG00000178568 ENSG00000196712 PMC1622889__F1 Anti-apoptosis of families of HSPs ENSG00000171791 PMC8799861__F6 CGAS–STING signaling in cardiovascular and metabolic diseases: Future novel target option for pharmacotherapy ENSG00000164430 ENSG00000136869 ENSG00000164342 PMC5983771__F1 Intracellular immune ecosystem in a virus infected cell ENSG00000213928 ENSG00000239732 ENSG00000088888 ENSG00000115415 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC8799861__F5 CGAS–STING signaling in cardiovascular and metabolic diseases: Future novel target option for pharmacotherapy ENSG00000278718 ENSG00000164430 ENSG00000150457 ENSG00000131023 PMC11655944__F2 Antitumor effects mechanism of EH ENSG00000087245 ENSG00000128272 ENSG00000125538 ENSG00000136997 ENSG00000136869 ENSG00000100219 ENSG00000100985 ENSG00000168610 PMC11655944__F3 Main components of EH Antitumor’s effects mechanism ENSG00000198793 ENSG00000123374 ENSG00000105810 ENSG00000166851 ENSG00000168610 ENSG00000146648 PMC4771656__F7 Signaling pathway of SFN in U251MG cells ENSG00000002330 ENSG00000175793 ENSG00000171791 PMC9563115__F1 Tumor-Associated Neutrophils in Colorectal Cancer Development, Progression and Immunotherapy ENSG00000178860 ENSG00000019991 ENSG00000169047 ENSG00000136869 ENSG00000168610 PMC3139800__F1 Regulation of endonuclease activity in human nucleotide excision repair ENSG00000132646 ENSG00000136936 ENSG00000122008 PMC10954797__F2 Graphical representation of stress signal-mediated dysregulation of p53 expression during progression from colitis to cancer ENSG00000149311 ENSG00000175054 PMC7873640__F1 Detail description of both canonical and noncanonical TGFB signaling and interaction of natural compounds in the regulation of this signaling cascade at various levels ENSG00000198793 PMC3918130__F5 Adenovirus elicits IFNAB production by a novel viral induction pathway ENSG00000239732 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC11966486__F1 CD28 signaling motifs mediate co-stimulatory signaling to regulate T cell function ENSG00000134982 ENSG00000113263 ENSG00000141968 PMC5836070__F2 Ethanol indirectly interferes with DNA integrity by affecting key points (labeled in red) or enzymes in folate metabolism ENSG00000228716 ENSG00000116984 PMC6867841__F7 Schematic picture depicting the effect of the immune factors on cysticercal brain infection ENSG00000150782 ENSG00000056558 ENSG00000131323 ENSG00000127191 PMC10954797__F4 ERCC4 may serve as an important regulatory factor for the upregulation of PD-L1 expression induced by DNA damage signals and DDR defects ENSG00000149311 ENSG00000175054 PMC7457324__F3 Metacore analysis reveals the top scored network of IL-6 pathway ENSG00000134339 ENSG00000175899 ENSG00000168610 PMC6606335__F5 Phase I/II Trial of Carfilzomib, Pegylated Liposomal Doxorubicin, and Dexamethasone for the Treatment of Relapsed/Refractory Multiple Myeloma ENSG00000002330 ENSG00000135116 ENSG00000254550 PMC7027163__F1 MAPK cascades ENSG00000142192 ENSG00000185591 PMC4599573__F8 PLB regulates remodeling of epithelial adherens junctions pathway in SCC25 cells.Notes: SCC25 cells were treated with 5 μM PLB for 24 hours and the protein samples were subject to quantitative proteomic analysis ENSG00000019991 ENSG00000134982 ENSG00000132341 PMC9158441__F5 Aconiti Lateralis Radix Praeparata as Potential Anticancer Herb: Bioactive Compounds and Molecular Mechanisms ENSG00000128272 ENSG00000144848 ENSG00000123374 ENSG00000100219 ENSG00000120868 ENSG00000168040 PMC4580090__F1 Role of STAT3 in lung cancer ENSG00000291971 ENSG00000168610 ENSG00000146648 PMC2953497__F9 Tumor Necrosis FactorA Regulates Distinct Molecular Pathways and Gene Networks in Cultured Skeletal Muscle Cells ENSG00000172831 ENSG00000074317 ENSG00000142178 ENSG00000163599 ENSG00000102575 ENSG00000118777 ENSG00000164105 ENSG00000211445 ENSG00000152056 ENSG00000154065 ENSG00000104804 ENSG00000133112 ENSG00000142089 ENSG00000122121 PMC6110912__F2 Summary of roles of different DUBs on the development of cardiac hypertrophy ENSG00000184979 ENSG00000083799 ENSG00000101557 PMC3547902__F2 Autocrine functions of VEGF in breast tumor cells ENSG00000118257 ENSG00000075213 ENSG00000065802 PMC4599573__F5 PLB regulates death receptor signaling in SCC25 cells.Notes: SCC25 cells were treated with 5 μM PLB for 24 hours and the protein samples were subject to quantitative proteomic analysis ENSG00000160789 ENSG00000106683 ENSG00000102871 ENSG00000138794 ENSG00000067900 ENSG00000120868 ENSG00000168040 ENSG00000127191 ENSG00000148935 ENSG00000111348 ENSG00000026103 ENSG00000160049 PMC6110912__F1 Summary of roles of different E3 ligases on the development of cardiac hypertrophy ENSG00000119401 ENSG00000150907 ENSG00000198793 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC4899619__F1 TGFB/Smad canonical signaling pathway ENSG00000134940 ENSG00000204217 PMC4599573__F2 PLB regulates cell cycle at G2/M checkpoint in SCC25 cells.Notes: SCC25 cells were treated with 5 μM PLB for 24 hours and the protein samples were subject to quantitative proteomic analysis ENSG00000149311 ENSG00000012048 ENSG00000123975 ENSG00000176386 ENSG00000087586 ENSG00000177519 ENSG00000277273 ENSG00000198625 PMC10704547__F2 AhR ligand-activated pathways mediate pro-cancer activities in breast cancer cells ENSG00000094631 ENSG00000104856 ENSG00000087245 ENSG00000262635 ENSG00000173757 ENSG00000164483 ENSG00000171759 ENSG00000168036 ENSG00000100985 ENSG00000140465 ENSG00000106546 PMC7912808__F6 Ingenuity pathway analysis of processes related to Barrett’s transcriptome ENSG00000245848 ENSG00000100290 ENSG00000135100 ENSG00000163914 ENSG00000164266 ENSG00000136869 ENSG00000127616 ENSG00000163507 PMC4599573__F1 Plumbagin suppresses epithelial to mesenchymal transition and stemness via inhibiting Nrf2-mediated signaling pathway in human tongue squamous cell carcinoma cells ENSG00000102034 ENSG00000198793 ENSG00000163914 PMC1978064__F4 MiR-103/107 and PANKs may constitute coordinated transcription units with synergistic cellular effects concerning cellular acetyl-CoA levels and other metabolic pathway elements ENSG00000131473 ENSG00000151726 ENSG00000135423 ENSG00000281324 ENSG00000161533 ENSG00000090857 ENSG00000169710 ENSG00000120137 ENSG00000120256 ENSG00000241878 PMC10704547__F1 AhR ligand-activated pathways mediate anticancer activities in breast cancer cells ENSG00000148400 ENSG00000135446 ENSG00000140505 ENSG00000124766 ENSG00000140465 ENSG00000106546 PMC7998316__F3 Simplified scheme highlighting processes in which PD-related proteins function in the endo-lysosomal pathway ENSG00000184381 ENSG00000111237 ENSG00000069329 PMC5605239__F6 Model for avoidance of APOBEC-induced lesions ahead of lagging strand DNA synthesis ENSG00000145321 PMC2834757__F9 Upregulation of SOCS-3 and PIAS-3 Impairs IL-12-Mediated Interferon-Gamma Response in CD56+ T Cells in HCV-Infected Heroin Users ENSG00000096996 ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000168610 ENSG00000139687 PMC2653380__F3 Schematic representation of bile acid synthesis by the classical neutral pathway ENSG00000242110 ENSG00000276559 ENSG00000198610 ENSG00000099377 ENSG00000135929 PMC10704547__F4 AhR ligand-activated pathways/genes exhibit anticancer or pro-cancer activity in breast cancer cells ENSG00000110711 ENSG00000087245 ENSG00000124766 ENSG00000100985 ENSG00000136826 ENSG00000121966 ENSG00000106546 PMC7004529__F1 Characteristics of cellular senescence ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC4302918__F3 Metabolic crosstalk between key signaling pathways in stem cells via ROS and other metabolic co-factors ENSG00000175567 ENSG00000096717 PMC7004529__F2 Biological function of senescence‐associated secretory phenotype (SASP) factors in physiological and pathological conditions ENSG00000108691 ENSG00000163739 PMC7004529__F3 CGAS‐STING pathway in senescence‐associated secretory phenotype (SASP) regulation ENSG00000183735 ENSG00000164430 PMC7214151__F3 Interaction between Rap2‐Hippo‐Yap1 pathway and TGF‐B signaling ENSG00000162733 ENSG00000168036 ENSG00000150457 ENSG00000131023 ENSG00000166033 PMC7460797__F2 1,25(OH)2D3 exerts neuroprotective effects via GDNF ENSG00000187871 PMC8566155__F1 Clinical Features and Pathophysiological Mechanisms of COVID-19-associated Gastrointestinal Manifestations ENSG00000131142 ENSG00000198793 ENSG00000184012 ENSG00000112115 PMC7243420__F2 From Beyond the Pale to the Pale Riders: The Emerging Association of Bacteria with Oral Cancer ENSG00000087095 ENSG00000169554 ENSG00000150907 PMC6217750__F4 Redox Regulation of Heme Oxygenase-2 and the Transcription Factor, Rev-Erb, Through Heme Regulatory Motifs ENSG00000171720 ENSG00000106400 ENSG00000069667 PMC8220152__F3 Deubiquitinating Enzymes Orchestrate the Cancer Stem Cell-Immunosuppressive Niche Dialogue: New Perspectives and Therapeutic Potential ENSG00000135655 ENSG00000124422 ENSG00000168283 ENSG00000168036 ENSG00000049768 ENSG00000168610 ENSG00000101557 PMC3651593__F1 Pathway of Fbw7-mediated degradation ENSG00000150991 ENSG00000100387 ENSG00000113558 PMC9342591__F1 Cast of characters ENSG00000150782 ENSG00000105329 ENSG00000188064 ENSG00000168036 PMC3392150__F1 Unfolded protein response and its role in intestinal homeostasis and inflammation ENSG00000128272 ENSG00000144895 ENSG00000169136 ENSG00000132478 ENSG00000127191 PMC12131435__F8 Intricate signaling interactions between cancer-associated fibroblasts (CAFs) and cancer cells, highlighting key pathways involved in tumor progression, proliferation, migration, and metastasis ENSG00000019991 ENSG00000107562 ENSG00000133110 ENSG00000124882 ENSG00000198793 ENSG00000156574 ENSG00000026508 ENSG00000162692 ENSG00000146648 ENSG00000291944 ENSG00000026103 PMC6340935__F1 The hexosamine biosynthetic pathway (HBP) leads to UDP-GlcNAc formation and regulates O-GlcNAcylation ENSG00000147162 ENSG00000198408 PMC10253447__F1 Notch signaling pathway inhibition leads to intestinal differentiation ENSG00000168214 ENSG00000114315 ENSG00000293532 ENSG00000172238 PMC5289527__F6 Whole genome sequencing of an African American family highlights toll like receptor 6 variants in Kawasaki disease susceptibility PMC2756960__F8 Effect of DLK1 and RTL1 but Not MEG3 or MEG8 on Muscle Gene Expression in Callipyge Lambs ENSG00000169047 ENSG00000198793 ENSG00000265972 ENSG00000140443 PMC4303637__F1 Metabolic reconstruction for Candidatus Iainarchaeum andersonii genome ENSG00000178860 ENSG00000104899 ENSG00000182511 ENSG00000079432 PMC4899619__F2 Multiple TGFB signaling pathways ENSG00000169291 ENSG00000135446 ENSG00000198793 PMC4899619__F3 TGFB and tumor suppression ENSG00000135446 ENSG00000205250 ENSG00000120868 ENSG00000105810 ENSG00000104081 PMC4438421__F3 TLR-ligand-mediated NFKB activation ENSG00000183735 ENSG00000172936 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC6814613__F8 Proposed signaling pathway of the study ENSG00000134853 ENSG00000171840 ENSG00000146648 PMC8777033__F3 Computational Framework to Identify Metabolic Engineering Strategies for the Co-Production of Metabolites ENSG00000144063 ENSG00000197713 ENSG00000122966 ENSG00000172005 PMC10253447__F2 Hedgehog signaling pathway in the development of intestinal metaplasia in the distal esophagus ENSG00000165556 ENSG00000170365 ENSG00000125398 ENSG00000117425 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 ENSG00000293532 PMC11767263__F1 Exercise alleviates sarcopenia by regulating multiple signaling pathways ENSG00000160097 ENSG00000134982 ENSG00000116688 ENSG00000168036 PMC5253284__F2 The unique biochemical aspects of MET-mediated bypass signaling driven by cell surface RTK aggregates leading to de-coupling of EGFR oncogenic function from its tyrosine kinase activity (alternate signaling) ENSG00000019991 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC4778288__F5 CRHR1 alterations in CRPS patients and schematic representation of miR-34a mediated repression of CRHR1 regulating POMC expression and BMI a CRHR1 was significantly higher in poor responders than in responders ENSG00000120088 ENSG00000115138 PMC6220113__F4 Illustration of lipoprotein alterations in chemotherapy recipients after 6 months ENSG00000042832 PMC6321489__F3 Scheme of the main steps for autophagy and their regulation by AMPK ENSG00000152348 ENSG00000123395 ENSG00000144848 ENSG00000155792 ENSG00000145782 PMC3166463__F1 RIGI-like receptor pathway ENSG00000088888 ENSG00000107201 ENSG00000131323 ENSG00000175104 ENSG00000276561 PMC12131435__F2 Process of normal fibroblasts transforming into CAFs can be described as follows: a Growth Factor and cytokine stimulation ENSG00000157933 ENSG00000197081 ENSG00000137033 ENSG00000291971 ENSG00000124882 ENSG00000078098 ENSG00000168610 PMC7109323__F6 Inhibition of PRRSV by LPS ENSG00000177575 ENSG00000136869 PMC3166463__F3 Innate immune signalling at the mitochondria ENSG00000174125 ENSG00000162711 ENSG00000088888 ENSG00000160703 ENSG00000136869 ENSG00000237693 ENSG00000130159 ENSG00000175104 PMC4534527__F1 Illustration of sonic hedgehog (SHH) signaling pathway ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC7765927__F2 Suggested interaction model between EBV and P ENSG00000087245 ENSG00000163739 ENSG00000198793 ENSG00000100985 PMC12131435__F1 Various regulated cell death mechanisms—ferroptosis (1), cuproptosis (2), and necroptosis (3)—influence the tumor microenvironment (TME) by shaping immune cell populations and modulating tumor progression ENSG00000134982 ENSG00000167468 ENSG00000188611 PMC3913057__F3 ErbBs/EGFR(s) signaling pathways ENSG00000177606 ENSG00000136997 ENSG00000185591 PMC8620049__F1 Influences of Omega-3 Polyunsaturated Fatty Acids on the Development of Skin Cancers ENSG00000157404 PMC8620049__F2 Influences of Omega-3 Polyunsaturated Fatty Acids on the Development of Skin Cancers ENSG00000128602 PMC3936782__F2 Neuroprotective/apoptotic intracellular cascades at baseline and as mitigated by mood stabilizers in BD ENSG00000002330 ENSG00000120868 ENSG00000084774 PMC3820259__F2 Roles of lipids in the tumour microenvironment ENSG00000169710 ENSG00000198670 ENSG00000026103 PMC8870715__F1 Recent Advances in Ovarian Cancer: Therapeutic Strategies, Potential Biomarkers, and Technological Improvements ENSG00000198793 ENSG00000146648 PMC8869227__F4 Cytoplasmic and Nuclear Functions of cIAP1 ENSG00000070831 ENSG00000102871 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000127191 PMC11724356__F2 NSCLC immunotherapy resistance ENSG00000089692 ENSG00000157764 ENSG00000198793 ENSG00000099810 ENSG00000273686 ENSG00000168610 ENSG00000146648 PMC8276205__F3 PD-L1 in the immune dysfunction that mediates hypoxia-induced multiple organ injury ENSG00000291603 ENSG00000198793 ENSG00000049768 ENSG00000124181 ENSG00000168610 PMC7662834__F7 Insulin signaling pathway ENSG00000171105 ENSG00000002330 PMC7576823__F3 Talin1 plays significant roles in cancer related pathway ENSG00000291971 ENSG00000198793 ENSG00000163914 ENSG00000177606 ENSG00000168036 PMC11666973__F6 Pattern diagram of H9N2 PB1 regulation of the RIG-I signaling pathway ENSG00000183735 ENSG00000088888 ENSG00000121060 PMC8870715__F2 Recent Advances in Ovarian Cancer: Therapeutic Strategies, Potential Biomarkers, and Technological Improvements ENSG00000168040 PMC8870715__F3 Recent Advances in Ovarian Cancer: Therapeutic Strategies, Potential Biomarkers, and Technological Improvements ENSG00000198382 ENSG00000126775 ENSG00000198793 ENSG00000005893 ENSG00000142082 PMC8573224__F5 In silico gene knockout prediction using a hybrid of Bat algorithm and minimization of metabolic adjustment ENSG00000261701 ENSG00000197713 ENSG00000122966 ENSG00000196839 ENSG00000172005 ENSG00000150787 ENSG00000062485 PMC7364809__F2 Signaling pathway of SGK1 in oncology ENSG00000162594 ENSG00000099901 ENSG00000150907 ENSG00000118515 ENSG00000170430 ENSG00000168036 ENSG00000107485 ENSG00000185591 ENSG00000049768 PMC6600269__F1 Survival signaling pathways related to the PI3K/Akt pathway in mouse macrophages ENSG00000002330 ENSG00000171791 PMC8573224__F4 In silico gene knockout prediction using a hybrid of Bat algorithm and minimization of metabolic adjustment ENSG00000261701 ENSG00000197713 ENSG00000122966 ENSG00000172005 ENSG00000150787 ENSG00000062485 PMC5056247__F1 Mitogen-activated protein kinase (MAPK) pathway and phosphoinositide 3 kinase (PI3K) pathway with downstream effectors ENSG00000002330 PMC4199593__F5 De Novo Transcriptome Sequencing of the Octopus vulgaris Hemocytes Using Illumina RNA-Seq Technology: Response to the Infection by the Gastrointestinal Parasite Aggregata octopiana ENSG00000110799 ENSG00000088926 ENSG00000166278 ENSG00000115718 ENSG00000178726 ENSG00000185010 ENSG00000182326 ENSG00000184500 ENSG00000180210 ENSG00000126218 ENSG00000101981 ENSG00000117525 ENSG00000057593 ENSG00000198734 PMC4767459__F2 Acyl-CoA synthetase-4, a new regulator of mTOR and a potential therapeutic target for enhanced estrogen receptor function in receptor-positive and -negative breast cancer ENSG00000157764 ENSG00000169047 ENSG00000198793 PMC4199593__F6 De Novo Transcriptome Sequencing of the Octopus vulgaris Hemocytes Using Illumina RNA-Seq Technology: Response to the Infection by the Gastrointestinal Parasite Aggregata octopiana ENSG00000198793 ENSG00000137193 ENSG00000130159 ENSG00000168040 ENSG00000150455 ENSG00000276561 ENSG00000183735 ENSG00000088888 ENSG00000115415 ENSG00000134070 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC4905168__F1 Noxa and cancer therapy ENSG00000128272 PMC7210406__F7 Proposed pathway of kynurenine effects on BMSCs ENSG00000107562 ENSG00000171720 ENSG00000121966 ENSG00000106546 PMC4199593__F7 De Novo Transcriptome Sequencing of the Octopus vulgaris Hemocytes Using Illumina RNA-Seq Technology: Response to the Infection by the Gastrointestinal Parasite Aggregata octopiana ENSG00000149311 ENSG00000138794 ENSG00000164399 ENSG00000120868 ENSG00000171791 ENSG00000064012 ENSG00000164305 PMC9476726__F9 Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer ENSG00000198793 PMC7827270__F2 Action of Oxaliplatin: L-OHP is transported into the cell by solute carrier family 31 (copper transporter), member 1 (SLC31A1) ENSG00000012061 ENSG00000104884 ENSG00000136868 PMC9476726__F7 Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer ENSG00000163914 ENSG00000198670 ENSG00000131023 PMC3894232__F3 JAK2-STAT5B pathway and osteoblast differentiation ENSG00000112964 PMC4776098__F1 Predicted molecular signaling guiding photoreceptor cell migration following transplantation into damaged retina ENSG00000094631 ENSG00000092445 ENSG00000134215 ENSG00000169710 ENSG00000112118 ENSG00000073111 ENSG00000134086 ENSG00000150907 ENSG00000136997 ENSG00000115507 ENSG00000184304 ENSG00000173406 ENSG00000100345 ENSG00000213341 ENSG00000168938 ENSG00000121774 ENSG00000166224 ENSG00000146648 ENSG00000107562 ENSG00000181163 ENSG00000291971 ENSG00000183625 ENSG00000198793 ENSG00000170558 ENSG00000168036 ENSG00000169032 ENSG00000112715 ENSG00000121879 ENSG00000121966 ENSG00000038382 ENSG00000105894 ENSG00000078747 ENSG00000149269 ENSG00000128052 ENSG00000037280 ENSG00000283060 ENSG00000143333 ENSG00000124181 ENSG00000125968 ENSG00000215301 ENSG00000168028 ENSG00000157764 ENSG00000168610 ENSG00000137841 ENSG00000122566 ENSG00000176884 ENSG00000177189 ENSG00000115415 ENSG00000067606 ENSG00000134853 ENSG00000165409 PMC9476726__F5 Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer ENSG00000105397 ENSG00000198793 ENSG00000187266 PMC4776098__F2 Predicted molecular signaling guiding photoreceptor cell migration following transplantation into damaged retina ENSG00000094631 ENSG00000167601 ENSG00000107562 ENSG00000181163 ENSG00000183625 ENSG00000169047 ENSG00000198793 ENSG00000170558 ENSG00000163064 ENSG00000168036 ENSG00000169710 ENSG00000171791 ENSG00000121966 ENSG00000134086 ENSG00000157227 ENSG00000163558 ENSG00000149269 ENSG00000136997 ENSG00000197386 ENSG00000143333 ENSG00000215301 ENSG00000168028 ENSG00000104365 ENSG00000213341 ENSG00000067900 ENSG00000168610 ENSG00000160691 ENSG00000122566 ENSG00000173757 ENSG00000010810 ENSG00000167996 ENSG00000146648 PMC9476726__F6 Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer ENSG00000164161 ENSG00000164690 ENSG00000128602 PMC9476726__F3 Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer ENSG00000002330 ENSG00000005882 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC9476726__F4 Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer ENSG00000134982 ENSG00000183579 ENSG00000168036 PMC3587995__F2 p53/p21/pRb/E2F and p16/pRb/E2F signaling pathway ENSG00000168283 ENSG00000135446 PMC9476726__F2 Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer ENSG00000102871 ENSG00000172936 ENSG00000130159 ENSG00000168040 ENSG00000127191 PMC3894232__F2 JAK2-STAT5B pathway and osteoblast differentiation ENSG00000112964 ENSG00000173757 PMC4824608__F1 Various possible mechanisms of Ca2+-ITPR-mediated control of autophagy ENSG00000177169 ENSG00000083290 ENSG00000198793 ENSG00000090674 ENSG00000112561 ENSG00000171791 PMC9008778__F4 Thrombosis and Inflammation—A Dynamic Interplay and the Role of Glycosaminoglycans and Activated Protein C ENSG00000162711 ENSG00000150782 ENSG00000110799 ENSG00000173599 ENSG00000163737 PMC9008778__F5 Thrombosis and Inflammation—A Dynamic Interplay and the Role of Glycosaminoglycans and Activated Protein C ENSG00000143799 ENSG00000162711 ENSG00000134982 ENSG00000125538 ENSG00000173599 PMC4377021__F10 Relevant crosstalk of altered signaling pathways involved in cell death for PTC and ATC ENSG00000182718 ENSG00000197747 ENSG00000141448 ENSG00000033800 ENSG00000196154 ENSG00000118257 PMC8934861__F5 Analysis of Gene Expression Profiles in the Liver of Rats With Intrauterine Growth Retardation ENSG00000150991 ENSG00000145384 ENSG00000100979 ENSG00000165269 PMC4606863__F1 Eicosanoid Storm in Infection and Inflammation ENSG00000283887 ENSG00000104321 ENSG00000196689 PMC9124149__F1 Mitochondrial Malfunction in Alzheimer's Disease: New Therapeutic Hope ENSG00000116688 ENSG00000171109 ENSG00000214253 PMC4459756__F3 Risk loci of human autoimmune diseases associated with the TFH developmental pathway ENSG00000162594 ENSG00000138378 ENSG00000156127 ENSG00000140968 ENSG00000113302 ENSG00000168811 ENSG00000168610 PMC4606863__F3 Eicosanoid Storm in Infection and Inflammation ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC3420349__F1 P53 signaling pathway: In normal conditions (black arrows), p53 is maintained at very low levels ENSG00000149311 ENSG00000175054 ENSG00000132646 PMC8117096__F3 CGAS-STING Pathway: Novel Perspectives in Liver Diseases ENSG00000183735 ENSG00000164430 PMC5412459__F1 Isotopomer formation through carbon distribution of [1,2-13C2]-glucose ENSG00000122966 ENSG00000173599 ENSG00000172005 PMC5296735__F5 Integrated Analysis of LncRNA-mRNA Co-Expression Profiles in Patients with Moyamoya Disease ENSG00000163464 ENSG00000119535 ENSG00000161921 ENSG00000292357 PMC7661711__F2 PTRH2: an adhesion regulated molecular switch at the nexus of life, death, and differentiation ENSG00000008710 ENSG00000198793 ENSG00000171791 ENSG00000141378 PMC6584781__F1 Signaling pathways that converge on p38 mitogen-activated protein kinase (MAPK) activation and formation of plexiform-like lesions in pulmonary arterial hypertension (PAH) ENSG00000042832 ENSG00000100985 ENSG00000168610 ENSG00000150630 PMC7816286__F6 Potential signaling pathway by which CD90 regulates biological behavior and energy metabolism in gastric cancer cells ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000283100 PMC7186402__F1 Classic control network of ferroptosis ENSG00000168003 ENSG00000151012 ENSG00000133937 ENSG00000205221 ENSG00000113161 ENSG00000111684 ENSG00000122873 ENSG00000074771 ENSG00000023909 ENSG00000115107 PMC8382288__SF1 Dual regulation of osteoclastogenesis and osteogenesis for osteoporosis therapy by iron oxide hydroxyapatite core/shell nanocomposites ENSG00000178860 ENSG00000137834 ENSG00000175104 ENSG00000131196 PMC8992566__F1 Resistance to second generation antiandrogens in prostate cancer: pathways and mechanisms PMC8992566__F4 Resistance to second generation antiandrogens in prostate cancer: pathways and mechanisms ENSG00000119547 ENSG00000291971 ENSG00000141639 ENSG00000168036 ENSG00000087586 ENSG00000168610 ENSG00000139687 PMC3549674__F1 New and emerging treatments for estrogen receptor-positive breast cancer: focus on everolimus ENSG00000291971 ENSG00000155792 ENSG00000146648 ENSG00000140443 PMC8879274__F1 Potential to Fight Obesity with Adipogenesis Modulating Compounds ENSG00000109819 ENSG00000245848 ENSG00000162337 ENSG00000134853 ENSG00000168036 ENSG00000128602 ENSG00000281857 ENSG00000132170 PMC7354287__F7 Androgen-binding AR inhibits TGF-Beta-related Pathway ENSG00000168036 PMC11572637__F1 Elafibranor on alcohol-associated liver disease in mice ENSG00000136869 PMC7565591__F3 Coupling of signal transduction and (default) pathways affecting mRNP formation and mRNA fate ENSG00000114127 ENSG00000172795 ENSG00000175104 ENSG00000272886 PMC2999229__F1 Hypothetical model for the molecular signaling pathways of vasculogenic mimicry in tumors and anti-vasculogenic mimicry (VM) therapy strategies ENSG00000087245 ENSG00000142627 ENSG00000069482 ENSG00000156574 ENSG00000133134 PMC10379376__F2 Pluripotency-Associated microRNAs in Early Vertebrate Embryos and Stem Cells ENSG00000071564 ENSG00000183283 ENSG00000143768 ENSG00000243709 ENSG00000135446 ENSG00000156574 ENSG00000183864 ENSG00000105810 ENSG00000134046 ENSG00000118971 PMC5399913__F3 Anti-recombination and anti-crossover activities of Srs2 during replication and HR mediated DSB repair ENSG00000132646 ENSG00000051180 PMC7191165__F2 Classic UPR signaling pathways ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC7604572__F1 ATP drives ATPase pump, membrane potential and Hh patterning ENSG00000122882 ENSG00000128602 PMC11927159__F3 SLC7A11 Inhibitors Represent a Promising Therapeutic Target by Facilitating the Induction of Ferroptosis in Breast Cancer ENSG00000167468 ENSG00000115107 ENSG00000115419 PMC3307887__F1 Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells ENSG00000026508 ENSG00000168610 PMC3668058__F6 Schematic representation of interacting fatty acid metabolic pathways in wild-type, D1, and D1o3-3 leaves ENSG00000173599 ENSG00000285482 ENSG00000198670 PMC11927159__F1 SLC7A11 Inhibitors Represent a Promising Therapeutic Target by Facilitating the Induction of Ferroptosis in Breast Cancer ENSG00000115884 ENSG00000167468 ENSG00000120868 PMC5495058__F2 Signaling pathway in sea urchin sperm ENSG00000145321 PMC4469332__F3 The production of BH4 within the DRG plays a critical role in pain signaling ENSG00000116096 PMC6785123__F5 Illuminating biological pathways for drug targeting in head and neck squamous cell carcinoma ENSG00000147044 ENSG00000077522 ENSG00000010810 ENSG00000172005 ENSG00000106299 ENSG00000198087 ENSG00000130402 ENSG00000072110 ENSG00000071051 ENSG00000105647 ENSG00000121879 ENSG00000161270 PMC5399913__F1 Role of Srs2 in the promotion of PRR ENSG00000132646 ENSG00000070950 ENSG00000051180 PMC4469332__F2 Intracellular levels of BH4 depend on three production conduits the de novo synthesis pathway, the recycling pathway and the salvage pathway ENSG00000228716 ENSG00000111537 ENSG00000242689 ENSG00000128342 ENSG00000150787 ENSG00000116096 PMC8043057__F1 Interactions of proteins encoded by studied genes in COVID-19 ENSG00000281244 ENSG00000178726 ENSG00000062485 PMC3493385__F2 RNAseq Analysis of the Parasitic Nematode Strongyloides stercoralis Reveals Divergent Regulation of Canonical Dauer Pathways ENSG00000157933 ENSG00000196839 ENSG00000118515 ENSG00000189430 ENSG00000096264 PMC4553214__F2 IPA analysis based hnRNPD networks in oral cancer ENSG00000291931 ENSG00000073584 ENSG00000204842 ENSG00000100220 ENSG00000105193 ENSG00000198793 ENSG00000089157 ENSG00000197451 ENSG00000129351 ENSG00000117713 ENSG00000100028 ENSG00000066044 ENSG00000149273 ENSG00000284254 ENSG00000088247 ENSG00000139613 ENSG00000169813 ENSG00000215301 ENSG00000165119 ENSG00000164587 ENSG00000092847 ENSG00000109654 ENSG00000177733 ENSG00000276833 ENSG00000092199 ENSG00000121774 ENSG00000147274 ENSG00000070756 ENSG00000065978 ENSG00000168066 ENSG00000102034 ENSG00000092841 ENSG00000138668 ENSG00000123908 PMC10379376__F5 Pluripotency-Associated microRNAs in Early Vertebrate Embryos and Stem Cells ENSG00000071564 ENSG00000116539 ENSG00000088305 ENSG00000150457 ENSG00000178691 PMC11608829__F6 miRNAs and circRNAs role in pathogenesis ENSG00000245848 PMC5611871__F1 AMPK-activating drugs that reduce cellular ATP levels, such as the antidiabetic metformin, promote tumor suppressive actions in a LKB1-dependent manner ENSG00000198793 ENSG00000155792 ENSG00000167965 PMC4946926__F10 The proposed model for production of IFNB in response to extracellular dsRNA ENSG00000183735 ENSG00000291971 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC5436728__F1 Deconstructing the Complexity of TGFB Signaling in Hematopoietic Stem Cells: Quiescence and Beyond ENSG00000163914 PMC7303082__F6 Adenosine affects the B cell receptor pathway ENSG00000197943 ENSG00000010671 PMC4284624__F1 ITCH E3 ligase in ATM network ENSG00000149311 ENSG00000078747 ENSG00000177606 ENSG00000131023 PMC8206147__F8 Schematic diagram of METTL14-mediated lncRNA OIP5-AS1 implicated in the Progression of PTC ENSG00000145388 ENSG00000146648 PMC7084349__F1 Cellular mechanisms mediating activity-dependent translational control ENSG00000198793 ENSG00000284161 ENSG00000167658 PMC7084349__F2 Translational control in antidepressant action ENSG00000198793 ENSG00000284161 ENSG00000167658 PMC3828572__F8 mTOR plays critical roles in pancreatic cancer stem cells through specific and stemness-related functions ENSG00000198793 PMC5610547__F5 Metabolic pathways ENSG00000002330 ENSG00000099810 ENSG00000102172 ENSG00000062485 PMC8106838__F4 Therapeutic toolkit to modulate Notch signalling ENSG00000168214 PMC8106838__F2 Skin architecture and Notch pathway member distribution ENSG00000148400 ENSG00000074181 PMC8106838__F1 An overview of Notch maturation, activation and processing ENSG00000090402 ENSG00000168214 PMC6541695__F2 IGF-2 bioactivity at the surface of an ovarian granulosa cell ENSG00000159167 ENSG00000171105 ENSG00000197081 ENSG00000115457 ENSG00000169047 PMC7545699__F7 Schematic diagram illustrating the role of repression of FGF signaling in inducing Dnmt3b inhibition during early development of IVF embryos ENSG00000088305 ENSG00000185591 PMC9388540__F6 Molecular model of FMRP-mediated regulation in GSCs ENSG00000168036 ENSG00000111186 PMC2647163__F3 Advances on the Understanding of the Origins of Synaptic Pathology in AD ENSG00000171105 ENSG00000010810 ENSG00000198576 PMC5376330__F9 Aspirin-triggered resolvin D1 attenuates PDGF-induced vascular smooth muscle cell migration via the cyclic adenosine monophosphate/protein kinase A (cAMP/PKA) pathway ENSG00000171049 PMC8582326__F2 Microtubules as Major Regulators of Endothelial Function: Implication for Lung Injury ENSG00000094631 ENSG00000163539 ENSG00000163914 PMC10476430__F2 Underlying upstream and downstream mechanisms of cardiokines that mediate the heart-to-adipose tissue communication ENSG00000130164 ENSG00000163430 ENSG00000105550 ENSG00000198793 ENSG00000077782 ENSG00000108510 ENSG00000169174 PMC5577134__F3 Biosynthetic gene cluster and proposed biosynthetic pathway of ilamycins ENSG00000121897 ENSG00000039537 ENSG00000166278 PMC5244394__F9 Acetylcholine acts through M3 muscarinic receptor to activate the EGFR signaling and promotes gastric cancer cell proliferation ENSG00000138798 ENSG00000146648 PMC7022878__F10 Summary suggesting the mechanisms of LUT attenuated hepatotoxicity induced by PbAc ENSG00000007171 ENSG00000079999 PMC8457865__F8 WNT16 is Robustly Increased by Oncostatin M in Mouse Calvarial Osteoblasts and Acts as a Negative Feedback Regulator of Osteoclast Formation Induced by Oncostatin M ENSG00000145623 ENSG00000099985 ENSG00000002745 ENSG00000168610 ENSG00000160691 PMC2909029__F2 A possible mechanism for the inhibitory effect of p66Shc on mitogenic signaling ENSG00000138798 ENSG00000146648 PMC6135780__F1 Extracellular signalling roles of S1P ENSG00000205639 ENSG00000105656 ENSG00000183018 PMC7730311__F1 Immune interaction and metabolic character of tumor cells and the mechanism of immune checkpoint inhibitor and metabolic intervention ENSG00000118596 ENSG00000134982 ENSG00000077463 PMC4681601__F1 Molecular Pathways: Targeting IDO1 and Other Tryptophan Dioxygenases for Cancer Immunotherapy ENSG00000157404 ENSG00000239732 ENSG00000134982 ENSG00000198793 ENSG00000136869 ENSG00000049768 ENSG00000125347 ENSG00000106546 PMC3131061__F1 TIR and NFKB signaling pathways ENSG00000135960 ENSG00000186716 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC5663846__F1 Kynurenine pathway ENSG00000162882 ENSG00000106546 PMC3638621__F11 The pathway map of urea cycle ENSG00000081181 ENSG00000036473 PMC11552425__F2 Whole-exome sequencing in cerebrovascular diseases ENSG00000177465 ENSG00000139364 ENSG00000169105 ENSG00000086102 ENSG00000074181 ENSG00000139567 ENSG00000106397 ENSG00000164176 ENSG00000178104 ENSG00000137845 ENSG00000117983 ENSG00000182667 PMC9284488__F3 LPS-mediated atherosclerosis ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC11039815__F1 Harnessing the cGAS-STING pathway to potentiate radiation therapy: current approaches and future directions ENSG00000183735 ENSG00000164430 ENSG00000173638 ENSG00000103222 PMC6660578__F4 Genetic risk factors and synapse dysfunction in AD pathogenesis ENSG00000143801 ENSG00000120899 ENSG00000198087 ENSG00000197943 ENSG00000120885 ENSG00000073712 ENSG00000281879 ENSG00000073921 ENSG00000137845 ENSG00000158859 ENSG00000137642 PMC6125308__F2 c-Met/INSR crosstalk in hepatocytes ENSG00000019991 ENSG00000171105 ENSG00000169047 PMC2930673__F2 Transport of heme synthesis intermediates and heme in metazoans ENSG00000144659 ENSG00000066926 ENSG00000080819 ENSG00000115657 ENSG00000118777 ENSG00000156273 PMC5257030__F8 Scheme of the interaction between the intrinsic apoptosis, autophagy and stress response pathways governing the HepG2 response to CdS QDs ENSG00000126775 ENSG00000144848 ENSG00000120868 ENSG00000171791 PMC4817777__F5 Regulatory pathway leading to colon cancer–promoting splicing aberrations ENSG00000011304 ENSG00000136997 PMC8254267__F2 Gut microbiota-mediated immunomodulation in tumor ENSG00000226275 ENSG00000161921 ENSG00000172936 ENSG00000136869 ENSG00000049768 PMC2930673__F1 Cellular iron processing ENSG00000182511 ENSG00000135776 PMC7201932__F7 Graphical summaries ENSG00000105329 PMC8183409__F2 Mutations in PTEN and TSC1/2 are associated with dysregulation of translation and transcription PMC4019504__F5 Integrated Analysis of Genome-wide Copy Number Alterations and Gene Expression in MSS, CIMP-negative Colon Cancer ENSG00000087095 ENSG00000142192 ENSG00000156076 ENSG00000291971 ENSG00000026508 ENSG00000168036 ENSG00000104332 ENSG00000196628 PMC8997154__F2 Impact of Cannabinoid Compounds on Skin Cancer ENSG00000101255 ENSG00000171791 PMC5131753__F2 Possible mechanisms of ribosomal proteins L5 and L11 signaling to MDM2 PMC7477357__F1 Coagulation cascade and the fibrinolytic system ENSG00000180210 ENSG00000003436 ENSG00000134982 ENSG00000122194 PMC8152462__F4 Research Progress on Oxidative Stress and Its Nutritional Regulation Strategies in Pigs ENSG00000115415 ENSG00000136997 ENSG00000123268 PMC2920636__F5 Molecular networks over-represented by E ENSG00000214114 ENSG00000112651 ENSG00000011422 ENSG00000186340 ENSG00000109519 ENSG00000197958 ENSG00000136997 ENSG00000122194 ENSG00000104368 ENSG00000150630 PMC10297006__F2 Ezrin controls several major cellular functions through the regulation of downstream signaling transduction pathways ENSG00000163914 ENSG00000185591 ENSG00000126778 PMC2266794__F4 Integrative Genome-Wide Expression Analysis Bears Evidence of Estrogen Receptor-Independent Transcription in Heregulin-Stimulated MCF-7 Cells ENSG00000087095 ENSG00000172680 ENSG00000117650 ENSG00000149308 ENSG00000146648 PMC4617749__F4 Kyoto Encyclopaedia of Genes and Genomes (KEGG) annotated the Toll-Like Receptor Signalling Pathway as significantly enriched in the RNA-seq dataset for HC ENSG00000168040 ENSG00000150455 ENSG00000276561 ENSG00000143387 ENSG00000239732 ENSG00000115415 ENSG00000170458 ENSG00000187554 ENSG00000125538 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC4221383__F3 Developmental Pathways Activated in Melanocytes and Melanoma ENSG00000111837 ENSG00000136160 PMC5583221__F1 Mechanism of axon degeneration and sites of action of chemotherapeutic drugs ENSG00000157064 ENSG00000173614 PMC9395689__F7 RAGE pathway activation and function in chronic kidney disease and COVID-19 ENSG00000142192 ENSG00000143546 ENSG00000189403 ENSG00000198670 ENSG00000122194 PMC9395689__F5 RAGE pathway activation and function in chronic kidney disease and COVID-19 ENSG00000189403 ENSG00000096717 PMC9395689__F6 RAGE pathway activation and function in chronic kidney disease and COVID-19 ENSG00000108691 ENSG00000189403 PMC8430758__F4 Usage of Natural Volatile Organic Compounds as Biological Modulators of Disease ENSG00000170458 ENSG00000172936 ENSG00000136869 PMC9395689__F3 RAGE pathway activation and function in chronic kidney disease and COVID-19 ENSG00000148400 ENSG00000137672 PMC9395689__F4 RAGE pathway activation and function in chronic kidney disease and COVID-19 PMC4767650__F2 INHIBITOR OF APOPTOSIS PROTEINS AS INTRACELLULAR SIGNALING INTERMEDIATES PMC8430758__F6 Usage of Natural Volatile Organic Compounds as Biological Modulators of Disease ENSG00000002330 ENSG00000198793 ENSG00000136997 ENSG00000171791 ENSG00000168040 ENSG00000026103 PMC3983720__F8 Diagram of putative mDA differentiation pathway based on this and other studies ENSG00000170365 ENSG00000107859 ENSG00000162761 ENSG00000164690 PMC12140325__F8 KLF1 Promotes Cardiomyocyte Proliferation and Heart Regeneration through Regulation of Wnt/B‐catenin signaling Pathway ENSG00000281324 ENSG00000148773 ENSG00000105610 ENSG00000168036 ENSG00000087586 PMC8552907__F4 Enrichment analysis for specific cellular pathways ENSG00000072274 ENSG00000151092 ENSG00000111737 ENSG00000111229 ENSG00000084733 ENSG00000103266 ENSG00000130811 ENSG00000156675 ENSG00000224320 ENSG00000100934 ENSG00000242247 ENSG00000058262 ENSG00000084070 ENSG00000291836 ENSG00000244038 ENSG00000112208 ENSG00000100813 ENSG00000163634 ENSG00000115145 ENSG00000124783 ENSG00000116406 ENSG00000070831 ENSG00000205302 ENSG00000132182 ENSG00000113569 ENSG00000125676 ENSG00000168118 ENSG00000039319 ENSG00000102081 ENSG00000129515 ENSG00000205937 ENSG00000089597 ENSG00000130741 ENSG00000138750 ENSG00000197081 ENSG00000102900 ENSG00000074695 ENSG00000174740 ENSG00000139496 ENSG00000161203 ENSG00000163902 ENSG00000079134 ENSG00000183684 ENSG00000127022 ENSG00000184787 ENSG00000042753 ENSG00000155561 ENSG00000051596 ENSG00000149182 ENSG00000136243 ENSG00000291973 ENSG00000161960 ENSG00000170248 ENSG00000131652 ENSG00000164961 ENSG00000162385 ENSG00000196961 ENSG00000101310 ENSG00000138674 ENSG00000125844 ENSG00000055163 ENSG00000163527 ENSG00000183020 ENSG00000122705 ENSG00000130175 ENSG00000069345 ENSG00000108774 ENSG00000090520 ENSG00000141367 PMC5520455__F2 Schematic depiction of reported effects of mammalian caspases in autophagy-related effectors ENSG00000029363 ENSG00000144848 ENSG00000057663 PMC9656741__F3 PSEN2 Thr421Met Mutation in a Patient with Early Onset Alzheimer’s Disease ENSG00000112367 ENSG00000204842 ENSG00000151835 ENSG00000140090 ENSG00000137642 ENSG00000280616 ENSG00000284816 ENSG00000107290 ENSG00000132718 ENSG00000143801 ENSG00000106460 ENSG00000104133 ENSG00000074181 ENSG00000087589 PMC8170084__F1 Regulatory Mechanisms of the RNA Modification m6A and Significance in Brain Function in Health and Disease ENSG00000122566 ENSG00000145388 ENSG00000163435 ENSG00000164944 ENSG00000149658 ENSG00000162775 ENSG00000198492 ENSG00000275272 ENSG00000146457 ENSG00000092199 PMC4641911__F3 Schematic representation of a hypothetical pathway in neurodegeneration involving stress signaling to and from the Golgi ENSG00000164715 PMC4585638__F3 ‘Obesity’ is healthy for cetaceans? Evidence from pervasive positive selection in genes related to triacylglycerol metabolism ENSG00000125166 ENSG00000135218 ENSG00000145384 ENSG00000116906 ENSG00000137841 ENSG00000062282 ENSG00000166391 ENSG00000009950 ENSG00000138193 ENSG00000173599 ENSG00000114805 ENSG00000197142 ENSG00000115556 ENSG00000197943 ENSG00000198670 ENSG00000170231 ENSG00000179833 ENSG00000164398 ENSG00000276429 ENSG00000186281 ENSG00000198911 ENSG00000101333 PMC4711159__F2 Mechanisms regulating CD4+ and CD4+CD25+forkhead box protein 3 (FoxP3) balance ENSG00000134982 ENSG00000163599 ENSG00000049768 PMC11899884__F4 PI3K/AKT/mTOR-mediated autophagy by NPs in cancer therapy PMC5500564__F3 Differential gene expression in the tamoxifen metabolism pathway PMC5500564__F4 Differential gene expression in xenobiotics metabolism pathway between Asian American and Caucasian American ENSG00000159921 ENSG00000128951 ENSG00000124357 PMC9027240__F2 Target Therapy for Hepatocellular Carcinoma: Beyond Receptor Tyrosine Kinase Inhibitors and Immune Checkpoint Inhibitors ENSG00000166813 ENSG00000128602 PMC9027240__F3 Target Therapy for Hepatocellular Carcinoma: Beyond Receptor Tyrosine Kinase Inhibitors and Immune Checkpoint Inhibitors ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11899884__F1 PI3K/AKT/mTOR pathway in Cancer ENSG00000155792 PMC5811448__F9 Model linking the adaptive and innate immune responses during tumour development via IL-33-ILC2 axis ENSG00000169245 ENSG00000137033 ENSG00000115415 ENSG00000138755 PMC6278270__F1 The main molecular pathways linked to inflammatory and immunomodulatory activities modulated by Curcumin and Echinacea ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC3003336__F4 FLCN pathway ENSG00000002330 ENSG00000052795 ENSG00000217128 PMC6016849__F1 O-Linked Beta-N-acetylglucosamine (O-GlcNAc) Modification: A New Pathway to Decode Pathogenesis of Diabetic Retinopathy ENSG00000147162 ENSG00000198408 ENSG00000159399 ENSG00000013375 PMC9317121__F9 BMP Signaling Pathway in Dentin Development and Diseases ENSG00000170365 ENSG00000137834 PMC8631517__F9 EMS1/DLL4-Notch Signaling Axis Augments Cell Cycle-Mediated Tumorigenesis and Progress in Human Adrenocortical Carcinoma ENSG00000164283 ENSG00000128917 PMC5949932__F2 Regulating network of exosomal proteins and ncRNAs in tumors ENSG00000143546 ENSG00000058085 ENSG00000163220 ENSG00000143322 ENSG00000154721 ENSG00000100985 PMC4570614__F7 Dynamic differentially expressed (DE) genes were involved in T and B cell development as well as innate and adaptive immune response ENSG00000095585 ENSG00000096996 ENSG00000111537 ENSG00000134982 ENSG00000158825 ENSG00000172936 ENSG00000168040 PMC8781713__F6 LRG1: an emerging player in disease pathogenesis ENSG00000170365 ENSG00000159216 ENSG00000138798 ENSG00000168036 ENSG00000067900 ENSG00000168610 ENSG00000146648 PMC5876636__F2 TGFB1 signaling via SMAD-dependent/independent pathways ENSG00000105329 ENSG00000038427 ENSG00000152952 ENSG00000154096 PMC7797639__F7 [missing figure legend] ENSG00000138798 ENSG00000146648 ENSG00000161999 PMC1193608__F8 Model of HAV interaction with the dsRNA-induced IRF-3 activation pathway ENSG00000183735 ENSG00000164342 PMC6375072__F1 Molecular signaling mechanisms of nicotine mediated anti-inflammatory effects ENSG00000189403 ENSG00000168610 PMC4811984__F6 Reduced dopaminergic transmission in the mesolimbic pathway may overrule orexigenic signals from the arcuate nucleus ENSG00000198576 ENSG00000115138 PMC8346982__F2 Inflammation, Extracellular Matrix Remodeling, and Proteostasis in Tumor Microenvironment ENSG00000170961 ENSG00000026508 ENSG00000168036 ENSG00000068001 PMC8346982__F3 Inflammation, Extracellular Matrix Remodeling, and Proteostasis in Tumor Microenvironment ENSG00000120885 PMC5067692__F1 Newly synthesized FGFR1 can enter either the constitutive membrane pathway or regulated nuclear pathway in membrane pathway the receptor is processed and glycosylated in Golgi and accumulates in plasma membrane ENSG00000205221 PMC6689231__F2 Insulin signaling pathway ENSG00000140992 ENSG00000171105 ENSG00000169047 PMC6158369__F1 Primary and acquired resistance to CD38 antibodies ENSG00000196352 PMC8081604__F9 Polydatin Attenuates OGD/R-Induced Neuronal Injury and Spinal Cord Ischemia/Reperfusion Injury by Protecting Mitochondrial Function via Nrf2/ARE Signaling Pathway ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC10341681__F6 Signaling pathways and targets of saponins against apoptosis in AD ENSG00000005513 ENSG00000168036 ENSG00000127191 PMC7229901__F1 Treg-mediated suppression ENSG00000109321 ENSG00000181847 PMC9249680__F2 Engineering Yarrowia lipolytica to produce nutritional fatty acids: Current status and future perspectives ENSG00000173599 ENSG00000198670 ENSG00000128513 ENSG00000026103 PMC4265676__F7 Schematic model of WRAP53B function in the DDR pathway ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000163961 ENSG00000166402 ENSG00000051180 ENSG00000112130 PMC8133800__F1 Decorin as a possible strategy for the amelioration of COVID-19 PMC10341681__F2 Signaling pathways and targets of AB metabolism regulation by saponins ENSG00000167601 ENSG00000142192 ENSG00000112561 ENSG00000119912 ENSG00000137845 PMC10341681__F3 Signaling pathways and targets of saponin-regulated tau protein phosphorylation ENSG00000169047 ENSG00000205629 PMC8774728__F1 New Strategies and Combinations to Improve Outcomes in Immunotherapy in Metastatic Non-Small-Cell Lung Cancer ENSG00000164430 ENSG00000111537 ENSG00000181847 PMC10514522__F2 Microglial metabolism shifts from OXPHOX to glycolysis in the inflammatory state ENSG00000198793 ENSG00000172936 ENSG00000084774 PMC10341681__F4 Signaling pathways and targets of saponins against neuroinflammation in AD ENSG00000005513 ENSG00000086991 ENSG00000168036 ENSG00000123374 PMC10514522__F3 Lipid metabolism in microglia in the inflammatory state ENSG00000135218 ENSG00000130164 ENSG00000204498 ENSG00000026103 PMC10341681__F5 Signaling pathways and targets of saponins against oxidative stress in AD ENSG00000086991 ENSG00000168036 PMC10254162__F11 FAK/Src signaling pathway ENSG00000070831 ENSG00000291971 PMC8497485__F3 Myeloid-derived suppressor cells as immunosuppressive regulators and therapeutic targets in cancer ENSG00000115415 ENSG00000140968 ENSG00000125538 ENSG00000198793 ENSG00000172936 ENSG00000118520 ENSG00000168610 PMC3582104__F1 The intracellular signaling pathways modulated by somatostatin receptors ENSG00000291971 ENSG00000157005 PMC4593735__F1 Innate immune interactions within the central nervous system modulate pathogenesis of viral infections ENSG00000162711 ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000144895 ENSG00000172936 ENSG00000135828 PMC7484982__F3 Reign in the membrane: How common lipids govern mitochondrial function ENSG00000163624 ENSG00000184207 ENSG00000169230 ENSG00000087157 ENSG00000173599 ENSG00000084090 ENSG00000198670 ENSG00000111666 ENSG00000134255 ENSG00000144559 ENSG00000101166 ENSG00000101290 ENSG00000133027 PMC4996658__F2 Co-ordinating Notch, BMP, and TGFB Signalling During Heart Valve Development ENSG00000168214 PMC7484982__F4 Reign in the membrane: How common lipids govern mitochondrial function ENSG00000168958 ENSG00000113163 PMC5414836__F3 Cytokine Decoy and Scavenger Receptors as Key Regulators of Immunity and Inflammation ENSG00000137033 ENSG00000125538 ENSG00000198793 ENSG00000172936 ENSG00000168610 ENSG00000115594 PMC4996658__F3 Co-ordinating Notch, BMP, and TGFB Signalling During Heart Valve Development ENSG00000170365 PMC9230742__F6 Combined Transcriptomic and Proteomic Profiling to Unravel Osimertinib, CARP-1 Functional Mimetic (CFM 4.17) Formulation and Telmisartan Combo Treatment in NSCLC Tumor Xenografts ENSG00000099985 ENSG00000038002 ENSG00000168610 ENSG00000146648 PMC4975441__F4 Identification of Cell Type-Specific Differences in Erythropoietin Receptor Signaling in Primary Erythroid and Lung Cancer Cells ENSG00000187266 PMC8555376__F1 Race to stymie BTK: zanu zings ENSG00000107562 ENSG00000186716 ENSG00000198793 ENSG00000172936 ENSG00000168610 ENSG00000184216 ENSG00000010671 ENSG00000121966 ENSG00000198286 PMC11670978__F9 Pathway of action of HnAg in treating UC mice ENSG00000293532 ENSG00000106546 PMC11048596__F4 Significant Genes Associated with Mortality and Disease Progression in Grade II and III Glioma ENSG00000168028 ENSG00000163430 ENSG00000081237 ENSG00000147869 ENSG00000197471 ENSG00000112306 PMC11048596__F5 Significant Genes Associated with Mortality and Disease Progression in Grade II and III Glioma ENSG00000168028 ENSG00000039537 ENSG00000108298 ENSG00000185022 ENSG00000059804 ENSG00000175029 ENSG00000134574 ENSG00000163430 ENSG00000105640 ENSG00000050165 ENSG00000165879 ENSG00000112306 ENSG00000282899 ENSG00000172201 PMC4975441__F8 Identification of Cell Type-Specific Differences in Erythropoietin Receptor Signaling in Primary Erythroid and Lung Cancer Cells ENSG00000187266 PMC11711721__F7 Metabolomic and transcriptomic analyses revealed potential mechanisms of Anchusa italica Retz. in alleviating cerebral ischemia–reperfusion injury via Wnt/Beta-catenin pathway modulation ENSG00000134982 ENSG00000168036 PMC11048596__F6 Significant Genes Associated with Mortality and Disease Progression in Grade II and III Glioma ENSG00000170365 ENSG00000163430 ENSG00000134982 ENSG00000147869 ENSG00000165879 ENSG00000168036 PMC7031145__F7 Phosphoinositide-3-kinase, phosphatase and tensin homolog, p38 mitogen-activated protein kinase and RAS pathways modulated by caffeine ENSG00000198793 ENSG00000146648 PMC2834246__F2 Regulation of chromatin structure by drugs of abuse ENSG00000125740 ENSG00000108840 PMC3391582__F2 Signaling Circuitries Controlling Stem Cell Fate: To Be or Not To Be ENSG00000281324 ENSG00000162337 ENSG00000133067 ENSG00000198793 PMC2790539__F1 Apoptosis in cerebral ischemia and reperfusion ENSG00000002330 ENSG00000084774 ENSG00000026103 PMC3280275__F6 Kinome-Wide Functional Genomics Screen Reveals a Novel Mechanism of TNFAlpha-Induced Nuclear Accumulation of the HIF-1A Transcription Factor in Cancer Cells ENSG00000071575 ENSG00000092439 PMC7031145__F6 Inhibition of transforming growth factor B pathways caused by caffeine PMC5808116__F8 H. pylori T4SS induces potent IL-8 induction ENSG00000146648 PMC5029667__F7 PIM1 destabilization activates a p53-dependent response to ribosomal stress in cancer cells ENSG00000137193 ENSG00000198625 PMC11036351__F1 Hyper-Responsive Chemiluminescent Probe Reveals Distinct PYRase Activity in Pseudomonas aeruginosa ENSG00000069482 ENSG00000198125 PMC3794591__F5 Pathway map of fatty acid metabolism ENSG00000128513 PMC8165240__F1 Cannabinoid Signaling in Auditory Function and Development ENSG00000180210 ENSG00000100997 ENSG00000163686 ENSG00000164535 ENSG00000117480 ENSG00000100439 ENSG00000134780 ENSG00000006007 PMC5867015__F2 Signalling pathway of Pak1 in the heart ENSG00000070831 ENSG00000149269 PMC4405647__F13 Schematic presentation of molecular mechanisms by which acidosis controls the mTORC1 and eEF2K pathway to shut down protein synthesis and aid cancer cell survival ENSG00000284161 PMC9454586__F2 Oncostatin M: From Intracellular Signaling to Therapeutic Targets in Liver Cancer ENSG00000115415 ENSG00000168610 PMC8349405__F3 Antiviral strategies targeting host factors and mechanisms obliging +ssRNA viral pathogens ENSG00000088826 ENSG00000095059 ENSG00000148832 ENSG00000288145 ENSG00000129932 ENSG00000116649 ENSG00000102172 PMC3904630__F9 OTX2 loss causes rod differentiation defect in CRX-associated congenital blindness ENSG00000105392 ENSG00000285493 PMC8349405__F5 Antiviral strategies targeting host factors and mechanisms obliging +ssRNA viral pathogens ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172936 PMC9475269__F2 Amino acid metabolism in skeletal cells ENSG00000152266 ENSG00000128272 ENSG00000111371 ENSG00000115419 PMC9475269__F3 Amino acid metabolism in skeletal cells ENSG00000125398 ENSG00000157766 ENSG00000115419 PMC10961392__F2 Recent advances of myotubularin-related (MTMR) protein family in cardiovascular diseases ENSG00000102043 ENSG00000164430 ENSG00000285032 ENSG00000171100 ENSG00000139505 ENSG00000100330 ENSG00000108389 ENSG00000087053 ENSG00000063601 ENSG00000198626 PMC4645172__F5 Glatiramer acetate treatment negatively regulates type I interferon signaling ENSG00000226275 ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC6123652__F3 Mechanisms for stalled replication fork stabilization: new targets for synthetic lethality strategies in cancer treatments ENSG00000143799 ENSG00000138346 ENSG00000181544 ENSG00000147231 ENSG00000121988 ENSG00000077514 ENSG00000139618 ENSG00000012048 ENSG00000144554 ENSG00000165392 ENSG00000108384 ENSG00000051180 ENSG00000138375 ENSG00000111642 PMC3110186__F5 Unraveling Molecular Signatures of Immunostimulatory Adjuvants in the Female Genital Tract through Systems Biology ENSG00000111537 ENSG00000125538 ENSG00000172936 ENSG00000162924 ENSG00000135828 PMC2746238__F2 Induction of autoimmunity by pristane and other naturally-occurring hydrocarbons ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000121807 ENSG00000164342 PMC5987909__F4 Stiffness-induced acute lung injury and pulmonary hypertension ENSG00000163914 ENSG00000171759 ENSG00000143387 PMC3544185__F6 Complex Patterns of Altered MicroRNA Expression during the Adenoma-Adenocarcinoma Sequence for Microsatellite-Stable Colorectal Cancer ENSG00000288411 ENSG00000134982 ENSG00000113558 ENSG00000115718 PMC6541445__F3 Cellular mechanisms and signals that coordinate plasma membrane repair ENSG00000070831 ENSG00000163914 PMC10819745__F3 Pattern diagram of immune cell response process triggered by PRR signal triggered by HSV-1 infection ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000203485 ENSG00000163565 ENSG00000172005 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC7539815__F4 Proposed GnRH-analog effect on NAV3 and resultant effect on leiomyoma development ENSG00000109163 ENSG00000168036 ENSG00000067798 PMC6585524__F1 Photic signaling pathways involving main kinases activities in the circadian clock ENSG00000146469 ENSG00000145321 ENSG00000132326 ENSG00000179094 PMC6610579__F3 Schematic summary of molecular pathways induced by HBx-B genes ENSG00000108839 ENSG00000058085 ENSG00000118785 ENSG00000291971 ENSG00000149269 ENSG00000150907 ENSG00000137843 PMC5873314__F1 Theoretical model of how genetic polymorphisms influence symptom burden during breast cancer treatment PMC7724080__F2 Resistance to poly (ADP-ribose) polymerase inhibitors (PARPi) ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000083093 ENSG00000172716 ENSG00000080345 ENSG00000253251 ENSG00000171984 ENSG00000122376 ENSG00000227345 ENSG00000139618 PMC4335352__F5 Example of non-mitotic functions of Plk1: effects on the mTOR pathway ENSG00000177169 ENSG00000157764 PMC5535966__F8 G-protein signaling of LW pigs ENSG00000173599 ENSG00000010671 PMC8941195__F2 RAS/MAPK pathway PMC8941195__F3 a. PLCG signaling pathway and b. PI3K pathway ENSG00000140992 PMC7956994__F1 Complement system with focus on most relevant targets for therapeutic inhibition ENSG00000039537 ENSG00000113600 ENSG00000134830 ENSG00000203710 ENSG00000244731 ENSG00000166278 ENSG00000163661 ENSG00000132693 ENSG00000236625 PMC8027469__F2 Investigating the Underlying Mechanisms of Circular RNAs and Their Application in Clinical Research of Cervical Cancer ENSG00000184110 ENSG00000132646 ENSG00000150093 ENSG00000146648 ENSG00000198625 PMC4258146__F2 Canonical Wnt/Beta-catenin signaling ENSG00000281324 ENSG00000162337 PMC12238443__F2 Current model of the BR signaling pathway in Arabidopsis thaliana ENSG00000110934 PMC8431670__F3 UBL5/Hub1: An Atypical Ubiquitin-Like Protein with a Typical Role as a Stress-Responsive Regulator ENSG00000144554 PMC8036867__F2 Peroxisome proliferator-activated receptor gamma coactivator 1 (PGC-1A) in the onset of Parkinson’s disease ENSG00000158828 PMC7005498__F1 Cartoon Illustrating the UPR Pathway Involving Multiple Organelles and Three Branches, Several TFs, and Downstream Molecules Involved in Feedback Loops ENSG00000128272 ENSG00000144895 PMC11351691__F4 Hub proteins were obtained and verified by molecular docking ENSG00000105835 ENSG00000005339 ENSG00000157764 ENSG00000089041 ENSG00000121879 ENSG00000118777 ENSG00000106546 ENSG00000126218 ENSG00000141867 ENSG00000128052 ENSG00000095303 ENSG00000136869 ENSG00000146648 PMC8139654__F11 Microfilaments and Microtubules Alternately Coordinate the Multistep Endosomal Trafficking of Classical Swine Fever Virus ENSG00000106683 ENSG00000070831 ENSG00000149269 ENSG00000067900 ENSG00000146648 PMC7725584__F2 Active compound-potential target network ENSG00000114737 ENSG00000198793 ENSG00000087085 ENSG00000169710 ENSG00000171791 ENSG00000145386 ENSG00000112715 ENSG00000180210 ENSG00000126218 ENSG00000112038 ENSG00000100290 ENSG00000084676 ENSG00000082175 ENSG00000105810 ENSG00000087245 ENSG00000180720 ENSG00000086991 ENSG00000173039 ENSG00000007908 ENSG00000131095 ENSG00000073756 ENSG00000007171 ENSG00000132170 ENSG00000115850 ENSG00000177606 PMC11049935__F5 Plant hormone signaling pathways and related DEGs ENSG00000110934 ENSG00000221818 PMC2993603__F1 A tincture of hepcidin cures all: the potential for hepcidin therapeutics ENSG00000187045 ENSG00000128791 ENSG00000128342 ENSG00000168610 ENSG00000130513 PMC5076770__F2 The biological complexity of colorectal cancer: insights into biomarkers for early detection and personalized care ENSG00000019991 ENSG00000291971 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000100744 ENSG00000168610 PMC8683220__F2 Revisiting liquorice (Glycyrrhiza glabra L.) as anti-inflammatory, antivirals and immunomodulators: Potential pharmacological applications with mechanistic insight. ENSG00000162692 PMC5471631__F8 RIPK1 and RIPK3 kinases engage the IFN-I pathway downstream of the adapter protein TRIF ENSG00000183735 ENSG00000137275 ENSG00000136869 ENSG00000168404 ENSG00000285379 PMC6610579__F5 The schematic image of HBx/AKT/FOXO1 signaling pathway and AA metabolism induced inflammation ENSG00000108839 ENSG00000168036 PMC5683904__F7 Schematic to illustrate model of Wnt pathway ENSG00000281324 ENSG00000162337 ENSG00000129654 ENSG00000168036 PMC6851170__F9 The anti-TGEV effect of Lp-1s ENSG00000187608 ENSG00000115415 ENSG00000183486 ENSG00000135114 ENSG00000142166 PMC3073855__F1 Childhood Obesity – 2010: Progress and Challenges ENSG00000115138 ENSG00000170893 ENSG00000131096 PMC2837985__F9 Proposed model for the regulatory mechanisms of the Ras and cAMP signaling pathways in stress response and antifungal drug susceptibility in C ENSG00000070831 ENSG00000081277 ENSG00000063515 ENSG00000121211 PMC7432085__F5 Pathway studio network analysis of PLA2R1 and PLA2R1 promoter methylation in breast cancer ENSG00000136997 PMC9139316__F1 Detecting DNA: An Overview of DNA Recognition by Inflammasomes and Protection against Bacterial Respiratory Infections ENSG00000278718 ENSG00000162711 ENSG00000124256 ENSG00000183735 ENSG00000164430 ENSG00000163568 ENSG00000137757 ENSG00000125538 ENSG00000196954 ENSG00000163565 ENSG00000285379 PMC8113812__F3 Role of exosomes derived from serum in sepsis ENSG00000002330 ENSG00000125538 ENSG00000198793 ENSG00000189403 ENSG00000113520 ENSG00000172936 ENSG00000005381 ENSG00000026103 PMC8878749__SF2 Nanosized Codelivery System Based on Intracellular Stimuli-Triggered Dual-Drug Release for Multilevel Chemotherapy Amplification in Drug-Resistant Breast Cancer ENSG00000291814 ENSG00000026508 ENSG00000150787 PMC8113812__F5 Role of exosomes derived from epithelial and endothelial cells in sepsis ENSG00000125538 ENSG00000067900 ENSG00000175104 ENSG00000184216 PMC7560934__F1 Diagrammatic representation of Beta-cell function PMC8660205__F6 Network Pharmacology and Molecular Docking Study of Zhishi-Baizhu Herb Pair in the Treatment of Gastric Cancer ENSG00000177455 ENSG00000103479 ENSG00000142192 ENSG00000002330 ENSG00000069482 ENSG00000179091 ENSG00000104894 PMC5504167__F2 Corticotropin-releasing hormone (CRH) controls the placental “surveillance and response” system so that the fetus can detect threats to survival and adjust its developmental trajectory PMC6456712__F1 MHtt aggregation, generation of ER stress and the consequent UPR protective and later pro-apoptotic responses ENSG00000128272 ENSG00000144895 ENSG00000079999 PMC9700492__F5 Transcriptomic and metabolomic insights into the role of the flgK gene in the pathogenicity of Pseudomonas plecoglossicida to orange-spotted grouper (Epinephelus coioides) ENSG00000104856 ENSG00000125538 ENSG00000122877 ENSG00000197943 ENSG00000143933 ENSG00000131196 PMC4738349__F10 Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC4065342__F2 The biosynthesis pathway of the major terpenoids in plants ENSG00000197971 ENSG00000197429 ENSG00000082212 PMC2291295__F1 Keratinocyte Apoptosis in Epidermal Development and Disease ENSG00000026103 PMC4001725__F2 Estrogenic Steroid Hormones in Lung Cancer ENSG00000113905 ENSG00000291971 ENSG00000138798 ENSG00000198793 PMC3299342__F3 Signaling by PERK, IRE1, and ATF6 ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC9663996__F5 ROS-triggered endothelial cell death mechanisms: Focus on pyroptosis, parthanatos, and ferroptosis ENSG00000278718 ENSG00000162711 ENSG00000125538 ENSG00000189403 ENSG00000172936 PMC2291295__F2 Keratinocyte Apoptosis in Epidermal Development and Disease ENSG00000019991 ENSG00000002330 ENSG00000138798 ENSG00000146648 PMC12108044__F5 KEGG pathway enrichment analysis PMC9528626__F2 OxMIF: a druggable isoform of macrophage migration inhibitory factor in cancer and inflammatory diseases ENSG00000019582 ENSG00000291971 ENSG00000026508 ENSG00000121966 PMC7241622__F1 Intracellular signaling pathways examined (A) and the experimental protocol used (B) ENSG00000084093 ENSG00000042832 PMC12096500__F8 Proposed mechanism of PSVII treatment in psoriasis involves the modulation of the STAT3/NFKB signaling pathway and the regulation of pyroptosis ENSG00000278718 ENSG00000162711 ENSG00000150782 ENSG00000168610 PMC5322464__F3 MapMan overview of significant (FDR adjusted p ≤ 0.05 & log2 fold change ≥2) differentially expressed loci (SDEL) involved in biotic stress pathway, unique to PB1+Pi9, upon M ENSG00000105722 ENSG00000178860 PMC4556464__F2 Hedgehog signalling pathway showing development of TNBC ENSG00000128602 ENSG00000026103 PMC6279938__F1 Impact of i-proteasome subunits on innate immune signaling in myeloid cells ENSG00000239732 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000126353 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC6398499__F4 Crosstalk between Wnt, RA and related signaling pathways in orofacial clefts ENSG00000184254 ENSG00000070193 ENSG00000003137 ENSG00000281324 PMC4584337__F2 Comparison between the biosynthesis of isoprenoids in photosynthetic organisms (A) and the biosynthesis pathway proposed in haloarchaea (B) ENSG00000197429 ENSG00000166278 ENSG00000062485 PMC10375653__F2 Involvement of the SIRT1-NLRP3 pathway in the inflammatory response ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC2637651__F3 Transcriptomes in Healthy and Diseased Gingival Tissues ENSG00000087095 ENSG00000172680 ENSG00000170458 ENSG00000138798 ENSG00000099942 ENSG00000026103 PMC6400530__F2 Pathogen antioxidant networks: The examples of Mtb and T ENSG00000134982 ENSG00000100348 ENSG00000285250 PMC8899168__F7 4‐octyl Itaconate inhibits lipopolysaccharide (LPS)‐induced osteoarthritis via activating Nrf2 signalling pathway ENSG00000181019 ENSG00000079999 PMC9072026__F1 Intertwined Relation between the Endoplasmic Reticulum and Mitochondria in Ischemic Stroke ENSG00000132906 ENSG00000291983 ENSG00000128272 PMC10411465__F4 Alterations of polyunsaturated fatty acids metabolic pathways in AAD ENSG00000087245 ENSG00000100985 ENSG00000162692 PMC3161734__F3 Predicting the Physiological Role of Circadian Metabolic Regulation in the Green Alga Chlamydomonas reinhardtii ENSG00000197713 ENSG00000156110 ENSG00000196549 ENSG00000118520 ENSG00000036473 ENSG00000102977 PMC10411465__F2 Gut microbiota-derived metabolites in AAD ENSG00000226492 ENSG00000119929 PMC12035886__F1 Mechanism of histone modifications in regulating enzalutamide sensitivity in advanced prostate cancer ENSG00000104885 ENSG00000006459 PMC10411465__F3 Major amino acid metabolic pathway involves AAD ENSG00000087245 ENSG00000151376 ENSG00000081181 ENSG00000126457 ENSG00000100985 ENSG00000096717 PMC12035886__F2 Histone modifications drive neuroendocrine differentiation in prostate cancer ENSG00000168610 PMC8170620__F2 Roles of Host Noncoding RNAs in Mycobacterium tuberculosis Infection ENSG00000119408 ENSG00000156171 ENSG00000168610 ENSG00000072201 PMC9191761__F1 Non-canonical WNT signalling pathways ENSG00000169071 ENSG00000185483 PMC8170620__F4 Roles of Host Noncoding RNAs in Mycobacterium tuberculosis Infection PMC11700300__F2 Pathogenetic mechanisms of WT1 in AML ENSG00000136997 ENSG00000171791 PMC8170620__F1 Roles of Host Noncoding RNAs in Mycobacterium tuberculosis Infection ENSG00000112208 ENSG00000172936 ENSG00000175104 ENSG00000168610 PMC8385445__F1 Leigh Syndrome: A Tale of Two Genomes ENSG00000073578 ENSG00000130414 ENSG00000131495 ENSG00000136463 ENSG00000229833 ENSG00000166136 ENSG00000178127 ENSG00000006695 ENSG00000101247 ENSG00000205138 ENSG00000139180 ENSG00000164405 ENSG00000011295 ENSG00000213619 ENSG00000123545 ENSG00000184752 ENSG00000156170 ENSG00000189043 ENSG00000110717 ENSG00000284194 PMC5021578__F2 Genetic Alterations of D-Catenin/NPRAP/Neurojungin (CTNND2): Functional Implications in Complex Human Diseases ENSG00000070831 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC6398499__F1 Key components and potential pharmacological targets of Wnt signaling implicated in orofacial clefts ENSG00000138795 ENSG00000281324 ENSG00000169071 ENSG00000116729 ENSG00000102312 ENSG00000168036 ENSG00000167074 ENSG00000163132 ENSG00000276799 ENSG00000157240 PMC6398499__F2 Crosstalk between Wnt, Cdh1, Bmp, TgfB and Fgf signaling pathways in orofacial clefts ENSG00000136158 ENSG00000066468 ENSG00000105329 ENSG00000158055 ENSG00000163132 ENSG00000164690 ENSG00000077782 PMC2966547__F1 Homocysteine metabolic pathways PMC9394413__F3 Normal and Pathological NRF2 Signalling in the Central Nervous System ENSG00000012048 ENSG00000083093 ENSG00000254986 ENSG00000181019 ENSG00000167996 ENSG00000112182 ENSG00000171791 ENSG00000176153 ENSG00000023909 ENSG00000164294 ENSG00000156273 ENSG00000079999 PMC6398499__F3 Crosstalk between Wnt, Shh, primary cilia and other related signaling components in orofacial clefts ENSG00000137273 ENSG00000106571 ENSG00000156427 ENSG00000168036 ENSG00000164690 PMC7408991__F4 Redox homeostasis and metabolic shift through activation of the Nrf2-Keap1 pathway and regulation of the NAD+/NADH ratio by PM redox enzymes ENSG00000096717 ENSG00000079999 PMC6901795__F7 A schematic model of zbTRIM25-mediated RLR signaling pathway during RGNNV infection ENSG00000183735 ENSG00000088888 ENSG00000107201 ENSG00000131323 ENSG00000175104 ENSG00000121060 PMC3201744__F1 MiR-21, miR-126, and miR-148a directly or indirectly regulate DNMT1 in SLE CD4+ T cells.A ENSG00000172889 PMC6770264__F1 Bone metastasis physiopathology: implication of cancer cell-microenvironment interactions and therapeutic targets ENSG00000107562 ENSG00000121966 PMC6330604__F1 DSBR pathways and the effect of RAD51 paralog loss on pathway choice ENSG00000149311 ENSG00000051180 ENSG00000139618 PMC8405392__F4 Exploring targets and signaling pathways of paeonol involved in relieving inflammation based on modern technology ENSG00000277571 ENSG00000100906 ENSG00000149968 ENSG00000081237 ENSG00000173039 ENSG00000100985 ENSG00000275565 ENSG00000073756 ENSG00000163631 PMC2975945__F4 Characterization of the Human Pancreatic Islet Proteome by Two-Dimensional LC/MS/MS ENSG00000104856 ENSG00000226275 ENSG00000147862 ENSG00000162924 ENSG00000111321 ENSG00000150455 PMC6710350__F4 Microglial inflammatory responses by IFNB signaling ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000198793 ENSG00000168610 ENSG00000142166 PMC9394413__F2 Normal and Pathological NRF2 Signalling in the Central Nervous System ENSG00000100387 ENSG00000079999 PMC3763042__F1 Working model of renoprotective pathways activated by relaxin ENSG00000007171 PMC2975945__F2 Characterization of the Human Pancreatic Islet Proteome by Two-Dimensional LC/MS/MS ENSG00000137193 PMC5330146__F2 The SOLLI model predicts targets of therapy ENSG00000099194 ENSG00000121807 PMC8232256__F4 Advances in Chemokine Signaling Pathways as Therapeutic Targets in Glioblastoma ENSG00000108691 ENSG00000081041 ENSG00000121807 PMC4402485__F1 Interplay of the Gastric Pathogen Helicobacter pylori with Toll-Like Receptors ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC5283711__F1 Redifferentiating Thyroid Cancer: Selumetinib-enhanced Radioiodine Uptake in Thyroid Cancer ENSG00000198793 PMC3491909__F1 Critical Kinase Cascade in Neurological Disorders: PI 3-K, Akt, and mTOR ENSG00000124102 ENSG00000005882 ENSG00000198793 ENSG00000118515 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC5036404__F2 Schematic overview of the molecular pathways involved in necroptosis ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000164342 PMC9082937__F7 Bilirubin Improves Gap Junction to Alleviate Doxorubicin-Induced Cardiotoxicity by Regulating AMPK-Axl-SOCS3-Cx43 Axis ENSG00000167601 ENSG00000136869 PMC11232677__F7 KEGG pathway analysis of differentially expressed genes on cell cycle pathway in AML patient group with high beta-catenin levels vs controls ENSG00000085117 ENSG00000261857 ENSG00000164190 ENSG00000277273 ENSG00000101224 ENSG00000166851 ENSG00000129933 ENSG00000117399 ENSG00000140534 ENSG00000093009 ENSG00000145604 ENSG00000094804 ENSG00000172167 ENSG00000002822 ENSG00000134057 ENSG00000132646 ENSG00000081377 ENSG00000123374 ENSG00000164754 ENSG00000004897 ENSG00000112742 ENSG00000071539 PMC11232677__F8 KEGG pathway analysis of differentially expressed genes on signaling pathways regulating pluripotency of stem cells in AML patient group with low beta-catenin levels vs controls ENSG00000071564 ENSG00000136603 ENSG00000084093 ENSG00000080345 ENSG00000134982 ENSG00000156574 ENSG00000104290 ENSG00000168036 ENSG00000135111 ENSG00000128342 ENSG00000168610 ENSG00000204217 PMC3847898__F1 Wnt signaling pathways and the effects in mature synapses ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC2627520__F2 Biosynthesis of Natural and Hyperelongated Chondroitin Sulfate Glycosaminoglycans: New Insights into an Elusive Process ENSG00000123989 ENSG00000198108 ENSG00000131873 ENSG00000062485 PMC187486__F8 Effects of Cdk4 disruption on the pathways controlling senescence and transformation ENSG00000135446 ENSG00000123374 PMC5731654__F2 Impact of BRAFi on T cell response to melanomas ENSG00000157764 ENSG00000107165 PMC3742913__F5 Gene pathways revealed by comprehensive genomic profiling ENSG00000143799 ENSG00000124126 ENSG00000121807 ENSG00000170365 ENSG00000159216 ENSG00000156103 ENSG00000184995 ENSG00000157227 ENSG00000136869 ENSG00000064012 ENSG00000162892 ENSG00000189377 ENSG00000087245 ENSG00000262406 ENSG00000196954 ENSG00000125347 ENSG00000169245 ENSG00000186810 ENSG00000161921 ENSG00000134070 ENSG00000026508 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000107562 ENSG00000102871 ENSG00000291971 ENSG00000163739 ENSG00000183625 ENSG00000020633 ENSG00000150093 ENSG00000124875 ENSG00000166851 ENSG00000164305 ENSG00000141968 ENSG00000121966 ENSG00000137265 ENSG00000113520 ENSG00000185591 ENSG00000128342 ENSG00000120868 ENSG00000132906 ENSG00000099985 ENSG00000168487 ENSG00000116701 ENSG00000168040 ENSG00000105639 ENSG00000127191 ENSG00000168610 ENSG00000145839 ENSG00000135446 ENSG00000126353 PMC3319919__F2 Components of the TLR pathway and genes commonly induced during the innate immune response of zebrafish to bacterial infection ENSG00000132906 ENSG00000039537 ENSG00000170385 ENSG00000110330 ENSG00000158517 ENSG00000183735 ENSG00000136997 ENSG00000172005 ENSG00000125538 ENSG00000157625 ENSG00000172936 ENSG00000198734 ENSG00000100985 ENSG00000175104 ENSG00000090376 ENSG00000171560 ENSG00000184216 PMC3824029__F1 Peripheral Blood Mononuclear Cell Gene Expression in Chronic Obstructive Pulmonary Disease ENSG00000213658 ENSG00000285109 ENSG00000186716 ENSG00000113263 ENSG00000010671 PMC5528934__F2 Genes associated with paclitaxel (A) and gemcitabine (B) mechanism of action (direct targets, metabolizing enzymes), genes previously associated with resistance, and stable genes in the biological pathways targets ENSG00000002330 ENSG00000103222 ENSG00000188229 ENSG00000104833 ENSG00000171791 ENSG00000129187 ENSG00000077150 ENSG00000089685 ENSG00000122691 ENSG00000158825 ENSG00000135185 ENSG00000124574 ENSG00000171793 ENSG00000082556 ENSG00000101162 ENSG00000112759 ENSG00000268902 ENSG00000104081 ENSG00000144191 ENSG00000197506 ENSG00000117228 ENSG00000162368 ENSG00000138115 ENSG00000048392 ENSG00000167325 ENSG00000171848 ENSG00000073734 ENSG00000047849 PMC4342515__F1 ncRNAs affect Akt pathway in cell cycle ENSG00000149311 ENSG00000114113 ENSG00000135446 ENSG00000111653 ENSG00000123374 ENSG00000185591 ENSG00000105810 ENSG00000167182 ENSG00000118971 ENSG00000197562 PMC3137149__F1 Simplified model of the tuberous sclerosis complex signaling pathway ENSG00000198793 ENSG00000155792 PMC4435677__F2 Pathogenesis and prevention of hepatitis C virus-induced hepatocellular carcinoma ENSG00000133083 ENSG00000019991 ENSG00000088888 ENSG00000078900 ENSG00000138823 ENSG00000136869 ENSG00000112715 ENSG00000139687 ENSG00000124762 ENSG00000136231 PMC4342515__F2 ncRNAs affect CDKIs and Myc pathway in cell cycle ENSG00000088305 ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 ENSG00000118971 PMC9225019__F1 Review of Multiple Myeloma Genetics including Effects on Prognosis, Response to Treatment, and Diagnostic Workup ENSG00000112576 ENSG00000178573 ENSG00000118971 PMC5872179__F2 Proximal T-cell signaling cascade ENSG00000291603 ENSG00000177606 ENSG00000136997 ENSG00000162924 ENSG00000131096 ENSG00000141968 PMC5036404__F1 Schematic overview of the intrinsic and extrinsic arms of apoptotic signaling ENSG00000002330 ENSG00000102871 ENSG00000083799 ENSG00000171791 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC12060353__F8 Aseptic inflammation caused by acinar cell injury leads to local tissue hypoxia ENSG00000163739 ENSG00000108821 PMC8489222__F2 Targeting smooth muscle cell phenotypic switching in vascular disease ENSG00000141448 ENSG00000169047 ENSG00000141052 PMC8885929__F4 GAIT-GM integrative cross-omics analyses reveal cholinergic defects in a C. elegans model of Parkinson’s disease ENSG00000087085 PMC137498__F6 Regulation of Cdc25A by Chk1 ENSG00000123374 PMC3042531__F3 Regulation of Innate Immunity by signaling pathways emerging from the endoplasmic reticulum ENSG00000128272 ENSG00000172936 ENSG00000136869 ENSG00000100219 ENSG00000150455 PMC8489222__F4 Targeting smooth muscle cell phenotypic switching in vascular disease ENSG00000163914 ENSG00000150457 ENSG00000118971 ENSG00000131023 PMC3855094__F7 Systematically Studying Kinase Inhibitor Induced Signaling Network Signatures by Integrating Both Therapeutic and Side Effects ENSG00000157764 ENSG00000291971 ENSG00000135446 ENSG00000123374 ENSG00000113263 ENSG00000077782 ENSG00000168610 ENSG00000146648 PMC12176010__F1 Research progress on the regulation of autophagy in cardiovascular diseases by chemokines ENSG00000177169 ENSG00000083290 ENSG00000155792 ENSG00000167965 PMC3938021__F3 Dissecting the Molecular Basis of the Role of the O-Mannosylation Pathway in Disease: Alpha-Dystroglycan and Forms of Muscular Dystrophy ENSG00000117411 ENSG00000282880 PMC3524152__F2 Bacterial effector targets the TRAF6-NFKB pathway to modulate the acute inflammatory response to bacterial invasion of epithelial cells ENSG00000175104 PMC2757135__F1 Cholesterol transport in steroid biosynthesis: Role of protein-protein interactions and implications in disease states ENSG00000119655 ENSG00000141458 PMC3855094__F5 Systematically Studying Kinase Inhibitor Induced Signaling Network Signatures by Integrating Both Therapeutic and Side Effects ENSG00000157764 ENSG00000291971 ENSG00000135446 ENSG00000123374 ENSG00000113263 ENSG00000077782 ENSG00000168610 ENSG00000146648 PMC8194945__F1 Nephroprotective activity of natural products against chemical toxicants: The role of Nrf2/ARE signaling pathway ENSG00000178573 ENSG00000100387 ENSG00000125538 ENSG00000079999 PMC9146859__F2 Antiretroviral Therapy-Induced Dysregulation of Gene Expression and Lipid Metabolism in HIV+ Patients: Beneficial Role of Antioxidant Phytochemicals ENSG00000130164 ENSG00000073060 ENSG00000138135 ENSG00000113161 ENSG00000125686 ENSG00000084073 PMC4395516__F7 Reported interactions between factors associated with Peters anomaly ENSG00000107859 ENSG00000124479 ENSG00000088836 ENSG00000137203 ENSG00000004961 ENSG00000164093 ENSG00000187676 PMC7177266__F4 Speculated view of the melanin synthesis pathway ENSG00000101440 ENSG00000171791 ENSG00000100146 ENSG00000140090 PMC5772929__F1 Mechanism through which metformin exerts its antitumor effects (A) by reducing the level of insulin in serum to inhibit the PI3K/Akt/mTOR signaling pathway and (B) by activating AMPK to inhibit the mTOR pathway ENSG00000002330 ENSG00000198793 PMC6753625__F1 Common signaling pathway for IL-1 family cytokines ENSG00000137033 ENSG00000136694 ENSG00000175104 ENSG00000115594 PMC8250151__F1 Myeloid-Derived Suppressor Cells as a Potential Biomarker and Therapeutic Target in COVID-19 ENSG00000108691 ENSG00000198793 ENSG00000108688 ENSG00000118520 ENSG00000121807 PMC3250228__F3 FOLATE-ALCOHOL AND CANCER PATHWAY HYPOTHESES ENSG00000228716 ENSG00000130649 PMC8584156__F3 Drosophila melanogaster as a Model Organism to Study Lithium and Boron Bioactivity ENSG00000197429 ENSG00000168036 PMC3613936__F2 Striking the target in iron overload disorders ENSG00000187045 PMC3196888__F8 A model showing the overlapping functions of MMR and FA proteins in ICL and MMR ENSG00000175054 ENSG00000113318 ENSG00000095002 ENSG00000122512 PMC7967251__F4 Potential signaling interactions between LPA and p53 in transformed cells ENSG00000162836 ENSG00000198670 PMC7967251__F2 Crosstalk between the p53 and sphingolipid pathways.The complex interplay of p53 with key enzymes of the sphingolipid metabolic pathway in modulating DDR is shown above ENSG00000139624 ENSG00000149311 ENSG00000175054 ENSG00000172292 PMC4055201__F8 Schematic diagram illustrating the possible mechanisms responsible for CORM-2 effects on LPS-induced VCAM-1 expression in RASFs ENSG00000177606 ENSG00000172936 ENSG00000162692 ENSG00000175104 PMC7013392__F4 Representation of the targets of stemazole (ST) involved in the MAPK signaling pathway ENSG00000087095 ENSG00000170458 ENSG00000102871 ENSG00000130522 ENSG00000130159 ENSG00000127191 ENSG00000196712 ENSG00000026103 PMC10413047__F2 LncRNAs regulating the proliferation and apoptosis of NSCLC ENSG00000065978 ENSG00000198625 PMC10413047__F3 CASC9 and lncRNA UCA1 in drug resistance in NSCLC PMC4138268__F8 Schematic representation of smoke-provoked MUC1 glycosylation in regulation of MUC1-C/p120ctn interaction and adherens junction (AJ) disruption ENSG00000291971 ENSG00000139629 ENSG00000146648 PMC5323396__F1 TLR molecular cascade ENSG00000087095 ENSG00000172936 PMC5323396__F2 General overview of the Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5323396__F3 Proposed molecular talking points between TLRs, Wnt, and nuclear factorKB (NFKB) ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000033800 ENSG00000173039 ENSG00000168036 ENSG00000172936 ENSG00000162924 PMC3166557__F2 Planar Cell Polarity Pathway – Coordinating morphogenetic cell behaviors with embryonic polarity ENSG00000169071 ENSG00000100592 ENSG00000134982 ENSG00000163914 ENSG00000112655 ENSG00000168036 ENSG00000125084 PMC2998095__F7 ID2 in clock resetting PMC2877959__F3 Uric acid transport and disease ENSG00000047849 ENSG00000118777 PMC4590647__F7 rLGALS9 internalization and signaling in CRC ENSG00000169032 ENSG00000057663 PMC8172013__F1 Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000185269 ENSG00000104332 PMC7987655__F1 Tourette Syndrome Risk Genes Regulate Mitochondrial Dynamics, Structure, and Function ENSG00000141668 ENSG00000292254 PMC9496903__F7 ABA-LANCL1/2 Hormone-Receptors System Protects H9c2 Cardiomyocytes from Hypoxia-Induced Mitochondrial Injury via an AMPK- and NO-Mediated Mechanism ENSG00000096717 PMC5731985__F2 Mesenchymal stem cells in idiopathic pulmonary fibrosis ENSG00000178860 ENSG00000168036 ENSG00000169429 ENSG00000121966 PMC8059835__F8 Hippo signaling pathway in podocytes after GSK3B knockdown ENSG00000129474 ENSG00000186575 ENSG00000131023 ENSG00000169435 PMC7462725__F2 Pathophysiological processes that drive cyst formation and growth in renal tubular epithelial cells of the collecting duct in ADPKD and the mechanism of action of vasopressin V2 receptor antagonists and SST analogues ENSG00000198793 ENSG00000001626 PMC3047474__F1 Architecture of intestinal TD and TI IgA responses ENSG00000145777 ENSG00000162896 PMC3047474__F2 Innate IgA-inducing signaling pathways ENSG00000020633 ENSG00000172936 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC11931165__F8 Osteogenic differentiation of GLP-1RA on BMSCs ENSG00000162337 ENSG00000134982 ENSG00000291837 ENSG00000168036 PMC11036006__F4 Diagram of “component-target-pathway” ENSG00000087085 ENSG00000112715 ENSG00000135914 ENSG00000149295 ENSG00000158125 ENSG00000277571 ENSG00000184845 ENSG00000128052 ENSG00000064012 ENSG00000087245 ENSG00000262406 ENSG00000142192 ENSG00000138794 ENSG00000158748 ENSG00000086991 ENSG00000173083 ENSG00000085662 ENSG00000067900 ENSG00000073756 ENSG00000168610 ENSG00000274286 ENSG00000102468 ENSG00000138735 ENSG00000151617 ENSG00000196689 ENSG00000146648 ENSG00000113448 PMC6177612__F3 Metabolic pathways of arachidonic acid PMC9290242__F3 Mitochondrial adaptation in cancer drug resistance: prevalence, mechanisms, and management ENSG00000065911 ENSG00000100714 ENSG00000102967 ENSG00000115419 PMC8515898__F1 Comprehensive Analysis of Pyroptosis-Related Genes and Tumor Microenvironment Infiltration Characterization in Breast Cancer ENSG00000278718 ENSG00000162711 PMC3118759__F5 Alteration to activity of the Akt/GSK3B signalling pathway can explain a number of the changes observed in microarray analysis of flies expressing rCAG, rCUG and rAUUCU repeats in the nervous system ENSG00000197386 ENSG00000066427 PMC4615895__F6 The model for effect of miR-214 on osteoclastogenesis ENSG00000005882 PMC3353888__F1 Adrenergic Alpha-1 Pathway Is Associated with Hypertension among Nigerians in a Pathway-focused Analysis ENSG00000170214 ENSG00000123454 ENSG00000115138 ENSG00000141744 ENSG00000088256 PMC4139891__F1 In renal cancer cells, stem cell factor (SCF) binding to the c-Kit receptor (c-KitR) induces several signal transduction pathways that lead to its proliferation, invasion, survival, and angiogenesis ENSG00000169291 ENSG00000010810 ENSG00000198793 ENSG00000285246 ENSG00000171540 ENSG00000168610 PMC4214862__F1 PI3K/AKT/mT0R signaling pathway ENSG00000163435 ENSG00000002330 ENSG00000198793 ENSG00000164327 PMC5436942__F4 A) IPA analysis suggests the involvement of signaling by ITAMs (immunoreceptor tyrosine-based activation motifs) in the FcGR pathway at 24h ENSG00000105647 ENSG00000138071 ENSG00000089159 PMC6283278__F1 Mitochondrial quality control mechanisms as molecular targets in cardiac ageing ENSG00000116044 ENSG00000116688 ENSG00000158828 ENSG00000171109 ENSG00000106459 ENSG00000214253 PMC3397862__F7 Schematic representation for the up-regulating mechanism of NSC proliferation by modulating Notch signaling with Lewis X-containing glycans in NSCs ENSG00000148400 ENSG00000273529 ENSG00000133961 PMC6283278__F2 Mitochondrial quality control mechanisms as molecular targets in cardiac ageing ENSG00000133895 ENSG00000116044 ENSG00000158828 ENSG00000106459 ENSG00000183735 ENSG00000117525 ENSG00000239732 ENSG00000164430 ENSG00000116688 ENSG00000150907 ENSG00000096717 ENSG00000171109 ENSG00000214253 PMC5489563__F1 Action of thioester-containing proteins (TEPs) in mammals and mosquitoes ENSG00000291791 ENSG00000182326 PMC6283278__F3 Mitochondrial quality control mechanisms as molecular targets in cardiac ageing ENSG00000177169 ENSG00000112561 PMC9032523__F1 COVID-19: Are We Facing Secondary Pellagra Which Cannot Simply Be Cured by Vitamin B3? ENSG00000105835 ENSG00000123572 ENSG00000278488 ENSG00000138356 PMC6545170__F2 Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9032523__F3 COVID-19: Are We Facing Secondary Pellagra Which Cannot Simply Be Cured by Vitamin B3? ENSG00000105835 ENSG00000157064 ENSG00000173614 ENSG00000138356 PMC2999349__F3 Location of 2,4DNT impacted genes in the pathway association network ENSG00000182621 ENSG00000156475 PMC6695471__F1 Transcriptional regulation of carotenoid biosynthesis pathway (CBP) genes in photosynthetic tissues ENSG00000140451 ENSG00000167986 ENSG00000140543 PMC2790753__F1 Microarray data for the genes in the pathway coined from the central genes in the KEGG pathways ‘insulin signaling pathway’ and ‘adipocytokine signaling pathway’ ENSG00000151726 ENSG00000135218 ENSG00000282905 ENSG00000102871 ENSG00000288174 ENSG00000169710 ENSG00000157184 ENSG00000182473 ENSG00000150907 ENSG00000104365 ENSG00000067057 ENSG00000100906 ENSG00000269335 ENSG00000096088 ENSG00000173039 ENSG00000127191 ENSG00000168610 ENSG00000132170 ENSG00000181929 ENSG00000106617 ENSG00000110395 ENSG00000197142 ENSG00000159346 ENSG00000285070 ENSG00000124253 ENSG00000028137 PMC2724975__F6 Illustrating expansion results with ambiguity networks ENSG00000262634 ENSG00000065833 ENSG00000188404 PMC3759924__F2 Lin28/let-7 regulatory axis ENSG00000112576 ENSG00000083223 ENSG00000171105 ENSG00000135446 ENSG00000164327 ENSG00000134744 ENSG00000128191 ENSG00000113360 ENSG00000135097 PMC9031400__F3 Tumor Microenvironment in Glioma Invasion ENSG00000168610 PMC11085166__F2 Keap1-Nrf2 signalling pathway for gene expression control ENSG00000181019 ENSG00000005421 ENSG00000005381 ENSG00000079999 PMC5061804__F1 Cellular signalling upstream and downstream of mammalian target of rapamycin (mTOR) complexes ENSG00000177169 ENSG00000117525 ENSG00000123395 ENSG00000150907 ENSG00000198793 ENSG00000155792 ENSG00000140443 PMC8526643__F2 What signals the glyoxalase pathway in plants? ENSG00000065833 ENSG00000099246 PMC4143103__F2 Canonical and noncanonical TGFB signaling ENSG00000157933 PMC3372091__F3 Mechanisms underlying the biological effects of polyphenols ENSG00000079999 PMC7365993__F2 RAS-RAF pathway in relation to miR-31 and RASA1 ENSG00000146648 PMC6493850__F2 Putative mechanisms underlying the neuroprotective effects of TGF‐B1 against AB‐induced neurodegeneration ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC2679364__F6 OVARIAN CANCER ENSG00000157764 PMC12249743__F5 Representation of epidermal human cell infection by SARS-CoV-2 and antiviral mechanisms ENSG00000183735 ENSG00000164430 PMC6262606__F1 Nuclear factor-kappa B signaling pathway ENSG00000104856 ENSG00000186716 ENSG00000173039 ENSG00000111321 PMC3474261__F1 MTORC1 signaling and genetic mutations at specific sites in the pathway ENSG00000198793 PMC4890987__F14 Investigating the specific core genetic-and-epigenetic networks of cellular mechanisms involved in human aging in peripheral blood mononuclear cells ENSG00000162889 ENSG00000239732 ENSG00000135090 ENSG00000172936 ENSG00000100784 ENSG00000175104 PMC3403683__F1 T cell receptor (TCR)-mediated signalling pathway ENSG00000291603 ENSG00000213658 ENSG00000134982 ENSG00000010810 ENSG00000099864 PMC5905132__F2 Adversarial functional module (AFM) pairs ENSG00000114993 ENSG00000196961 ENSG00000175416 ENSG00000110395 ENSG00000163914 ENSG00000161203 ENSG00000042753 ENSG00000213977 ENSG00000131941 PMC4890987__F13 Investigating the specific core genetic-and-epigenetic networks of cellular mechanisms involved in human aging in peripheral blood mononuclear cells ENSG00000138795 ENSG00000099204 ENSG00000128272 ENSG00000126353 ENSG00000171033 ENSG00000102974 PMC6352437__F8 Schematic diagram on the molecular mechanism of the anti-adipogenic effect of 10-HDA in 3 T3-L1 preadipocytes ENSG00000042832 PMC4890987__F10 Investigating the specific core genetic-and-epigenetic networks of cellular mechanisms involved in human aging in peripheral blood mononuclear cells ENSG00000135446 ENSG00000177606 ENSG00000099942 ENSG00000123689 ENSG00000171606 ENSG00000136068 PMC11790572__F1 Shared immunopathologic mechanisms of the atopic march ENSG00000105329 ENSG00000137033 ENSG00000145777 ENSG00000166090 PMC3218055__F3 Proteomic Signatures of Human Oral Epithelial Cells in HIV-Infected Subjects ENSG00000168259 ENSG00000143320 ENSG00000145192 ENSG00000050405 ENSG00000092820 PMC7921839__F2 Diagram depicting the main proposed events in the autophagy pathway ENSG00000175054 ENSG00000152348 ENSG00000126775 ENSG00000057663 PMC11740111__F5 Analysis of the effects of TPBG-KD on signaling pathways using KEGG ENSG00000087095 ENSG00000169291 ENSG00000095739 ENSG00000100387 ENSG00000171444 ENSG00000134982 ENSG00000167941 ENSG00000108375 ENSG00000100211 ENSG00000196470 ENSG00000185269 ENSG00000163631 PMC11383167__F1 Biomarker validation in AGS ENSG00000275214 ENSG00000213928 ENSG00000134321 ENSG00000187608 ENSG00000088827 ENSG00000115415 PMC9688631__F3 Molecular Biomarkers of Malignant Transformation in Head and Neck Dysplasia ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC5341791__F3 Signaling pathways triggered by GDNF activation of the RET transmembrane receptor ENSG00000291971 ENSG00000244405 PMC3380091__F3 Endometrial androgen target gene set ENSG00000002330 ENSG00000110148 ENSG00000171241 ENSG00000170893 PMC7322088__F7 Enhancing tumor growth due to the Hippo pathway being interrupted by LATS2 O-GlcNAcylation ENSG00000186575 ENSG00000147162 ENSG00000150457 PMC6242950__F3 Caspase-dependent apoptosis pathways in myofibroblasts ENSG00000002330 ENSG00000163914 ENSG00000171791 ENSG00000168040 ENSG00000026103 PMC3654583__F1 The RIG-I/MAVS signaling pathway in cancer cell-selective apoptosis ENSG00000169245 ENSG00000088888 ENSG00000125347 PMC3113675__F7 Arginine methylation of G3BP1 regulates both Ctnnb1 mRNA and canonical Wnt/Beta-catenin signaling ENSG00000154342 ENSG00000126457 ENSG00000168036 ENSG00000161202 PMC4214635__F2 De Novo Mutations in Moderate or Severe Intellectual Disability ENSG00000116539 ENSG00000118007 ENSG00000184156 ENSG00000130294 ENSG00000136531 ENSG00000168036 ENSG00000136709 ENSG00000196628 ENSG00000156475 ENSG00000038382 ENSG00000197283 ENSG00000152217 ENSG00000215301 ENSG00000100811 ENSG00000101901 ENSG00000132612 ENSG00000085185 ENSG00000160877 ENSG00000197102 ENSG00000166862 ENSG00000008086 ENSG00000167552 ENSG00000198626 ENSG00000197694 ENSG00000131828 ENSG00000176884 ENSG00000148660 ENSG00000112640 ENSG00000292254 PMC9133251__F6 Modified natriuretic peptides and their potential roles in cancer treatment ENSG00000090402 ENSG00000173786 ENSG00000145321 PMC7755097__F3 Retinoic acid signaling pathway is identified by topographic transcriptomic analysis of NAcSh ENSG00000283887 ENSG00000187608 ENSG00000188064 ENSG00000159388 ENSG00000070669 ENSG00000121068 ENSG00000143320 ENSG00000092067 ENSG00000100219 ENSG00000179348 ENSG00000054523 ENSG00000154175 ENSG00000099204 ENSG00000114982 ENSG00000168137 ENSG00000160410 ENSG00000178105 ENSG00000008056 ENSG00000068971 ENSG00000108219 ENSG00000139219 ENSG00000150551 ENSG00000132465 ENSG00000291470 ENSG00000102878 ENSG00000107164 ENSG00000060656 ENSG00000102743 ENSG00000127124 ENSG00000143162 ENSG00000147601 ENSG00000108511 ENSG00000174059 ENSG00000109332 ENSG00000143198 ENSG00000168036 ENSG00000003137 ENSG00000027075 ENSG00000187569 ENSG00000137673 ENSG00000089041 ENSG00000091138 ENSG00000164082 ENSG00000134871 ENSG00000081189 ENSG00000065978 ENSG00000285007 ENSG00000139289 ENSG00000134121 ENSG00000101327 ENSG00000114315 PMC6947386__F2 Cellular calcium [Ca2+] homeostasis and signaling: Organelles and molecules that are involved in Ca2+ pathways ENSG00000167323 ENSG00000293604 ENSG00000156026 ENSG00000072315 ENSG00000138741 PMC4997072__F2 TLR signal transduction pathways ENSG00000183735 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC4406223__F4 Interaction of mTOR and Erk1/2 signaling to regulate oligodendrocyte differentiation ENSG00000141086 ENSG00000169047 ENSG00000102104 PMC8800007__F3 Targeted Cancer Therapy Based on Acetylation and Deacetylation of Key Proteins Involved in Double-Strand Break Repair ENSG00000143799 ENSG00000135372 ENSG00000096717 ENSG00000133422 PMC8421919__F2 Bioinformatical identification of key genes regulated by IGF2BP2-mediated RNA N6-methyladenosine and prediction of prognosis in hepatocellular carcinoma ENSG00000145912 ENSG00000142798 ENSG00000131153 ENSG00000123485 ENSG00000112118 ENSG00000257335 ENSG00000137563 ENSG00000145386 ENSG00000161888 ENSG00000164104 ENSG00000166508 ENSG00000146670 ENSG00000111665 ENSG00000159674 ENSG00000013810 ENSG00000167670 ENSG00000125037 PMC6876670__F2 Canonical WNT/Beta-catenin pathway: “on” and “off” states ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6876670__F3 WNT/Beta-catenin, TGFB1, PI3K-AKT, SMAD, and PPARG pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC7878545__F6 Summary of Treg-of-B (P) cell generation and their molecular mechanisms in alleviation of asthmatic inflammation ENSG00000089692 ENSG00000106546 PMC7476662__F4 Predicted genes in the MAPK signaling pathway targeted by downregulated serum miRNAs (miRNAs) in BD, sarcoidosis, and VKH ENSG00000157764 ENSG00000160551 ENSG00000102466 ENSG00000011485 ENSG00000081189 ENSG00000126458 ENSG00000182389 ENSG00000026103 PMC2953449__F3 Different effects of gut- and brain-derived serotonin on the osteoblast ENSG00000128272 PMC6876670__F6 Canonical WNT/Beta-catenin pathway, Warburg glycolysis, and cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3061549__F1 The classical and alternative selection pathways in the thymus ENSG00000049768 PMC3175541__F7 NK2 homeobox 1 (NKX2-1)–Sam Pointed Domain Ets-like Factor (SPDEF)–associated gene network analyzed using Ingenuity Pathway Analysis ENSG00000262406 ENSG00000005339 ENSG00000228278 ENSG00000109321 ENSG00000136352 ENSG00000229314 ENSG00000016490 ENSG00000111537 ENSG00000163394 ENSG00000006747 ENSG00000137076 ENSG00000135424 ENSG00000124664 PMC8950345__F1 Fanconi Anemia Pathway in Colorectal Cancer: A Novel Opportunity for Diagnosis, Prognosis and Therapy ENSG00000143799 ENSG00000131944 ENSG00000083093 ENSG00000144554 ENSG00000187790 ENSG00000112039 ENSG00000139618 PMC8950345__F2 Fanconi Anemia Pathway in Colorectal Cancer: A Novel Opportunity for Diagnosis, Prognosis and Therapy ENSG00000144554 ENSG00000187790 ENSG00000108384 ENSG00000051180 ENSG00000095002 ENSG00000122512 PMC5851908__F1 Regulatory network for p42.3 involvement in tumor cell apoptosis (red pathway indicates the maximally possible acting pathway) ENSG00000196754 ENSG00000002330 ENSG00000149269 ENSG00000196154 ENSG00000067900 ENSG00000127191 PMC4196247__F6 Role of long-chain and very-long-chain polyunsaturated fatty acids in macular degenerations and dystrophies ENSG00000118402 ENSG00000119915 ENSG00000066322 ENSG00000197977 PMC3832246__F1 TNFR1 signaling of cell survival/proinflammatory and apoptosis pathways. Upon TNF receptor activation, complexes I (survival pathway) and II (apoptosis) are formed ENSG00000169245 ENSG00000149968 ENSG00000118503 ENSG00000102871 ENSG00000082512 ENSG00000168040 ENSG00000162692 ENSG00000175104 ENSG00000127191 PMC5851908__F3 Regulatory network for p42.3 involvement in colorectal cancer cell apoptosis (the red pathway indicates the possible acting pathway for p42.3 involvement in cell apoptosis) ENSG00000132906 ENSG00000002330 ENSG00000134982 ENSG00000168036 ENSG00000164305 PMC3073571__F8 Cone-specific Visual Cycle ENSG00000121207 ENSG00000116745 ENSG00000197713 PMC6950849__F1 Central role of TORC1 signalling pathway and importance of wild alleles for yeast nitrogen consumption ENSG00000178295 ENSG00000144895 ENSG00000145723 PMC2916406__F7 New model for a novel role of p38 MAPK in the DNA damage response in cancer cells ENSG00000149311 ENSG00000175054 PMC6053314__F5 NFKB Activation in primary CNS lymphoma ENSG00000105369 ENSG00000007312 ENSG00000198793 ENSG00000137193 ENSG00000171791 ENSG00000168610 ENSG00000010671 ENSG00000292210 ENSG00000140379 ENSG00000186716 ENSG00000137265 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000198286 ENSG00000127074 PMC6943912__F1 Immunogenetic effects of low dose (CEM43 30) magnetic nanoparticle hyperthermia and radiation in melanoma cells ENSG00000189377 ENSG00000143185 ENSG00000102962 ENSG00000183625 ENSG00000274736 ENSG00000121807 ENSG00000277943 ENSG00000121966 ENSG00000186810 ENSG00000108691 ENSG00000131142 ENSG00000161921 ENSG00000137077 ENSG00000277236 ENSG00000108688 ENSG00000181374 ENSG00000126353 ENSG00000275095 ENSG00000112486 ENSG00000106178 PMC12132251__F4 Functional integrative gene-based enrichment for genes annotated to the meta-analyzed hypo- and hyper-methylated CpGs consistent across all three studies and across all LF phenotypes: GACRS, CAMP and VDAART ENSG00000168026 ENSG00000198939 ENSG00000182472 ENSG00000186847 ENSG00000173599 ENSG00000179820 ENSG00000005381 PMC6024579__F2 Hepatic cell death pathway and liver injury in response to high fat diet exposure ENSG00000125538 ENSG00000168040 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC5930509__F9 Proposed hypothetical model depicting the involvement of miR-424/503 cluster in the Activin signalling pathway by targeting SMAD7 PMC9701047__F6 Comparative transcriptomic analysis provides insights into the molecular basis underlying pre-harvest sprouting in rice ENSG00000062485 PMC2655379__F8 Potential role for Akt/FOXO signalling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle ENSG00000169047 PMC10221877__F8 Response of DA metabolic pathway to Cd stress in duckweed ENSG00000123454 ENSG00000141744 PMC6745137__F6 Mechanisms of Yi Guan Jian Decoction in Chronic Hepatitis B Patients with Liver Fibrosis ENSG00000004975 ENSG00000284774 ENSG00000090534 ENSG00000100410 ENSG00000157933 ENSG00000156983 ENSG00000141551 ENSG00000197892 ENSG00000175220 ENSG00000099364 ENSG00000120875 ENSG00000105443 ENSG00000160339 ENSG00000169710 ENSG00000118640 ENSG00000133884 ENSG00000130164 ENSG00000125538 ENSG00000072201 ENSG00000198952 ENSG00000071655 ENSG00000063978 ENSG00000125817 ENSG00000275385 ENSG00000197081 ENSG00000116329 ENSG00000173039 ENSG00000135093 ENSG00000188191 ENSG00000114126 ENSG00000176986 ENSG00000273772 ENSG00000124733 ENSG00000177606 ENSG00000271303 ENSG00000173846 ENSG00000186866 ENSG00000142002 PMC7078051__F4 Iron homeostasis disruption in HLRCC ENSG00000134086 ENSG00000100387 ENSG00000167996 ENSG00000079999 PMC4049860__F3 CCM1 and the second life of proteins in adhesion complexes ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3973244__F7 Role of RNase L and TLR3 activation during inflammation in insulin response of obese people's myotubes ENSG00000169047 ENSG00000172936 ENSG00000136869 ENSG00000135828 ENSG00000164342 PMC7815887__F2 T2 inflammatory pathway (eosinophilic COPD and asthma) and the target sites for anti-IL-5 agents ENSG00000137033 ENSG00000107485 ENSG00000145777 ENSG00000166090 PMC6210917__F7 Tsc3 regulates the balance between canonical and noncanonical SPLs by promoting l-alanine incorporation into the SPL de novo synthesis pathway ENSG00000228278 ENSG00000229314 PMC8011202__F1 Insulin and pharmacological agents on endothelial insulin signaling ENSG00000159224 ENSG00000197635 PMC5568011__F7 MicroRNA-206 prevents hepatosteatosis and hyperglycemia by facilitating insulin signaling and impairing lipogenesis ENSG00000171105 ENSG00000169047 ENSG00000185591 ENSG00000196396 PMC2725943__F7 A model of mammalian Hh signaling ENSG00000106571 ENSG00000121067 ENSG00000128602 PMC9547905__F4 Hybrid network of genetic associations revealed by gene-based association studies and significant partial correlations of detected sphingomyelins, ENSG00000063176 ENSG00000166224 ENSG00000285281 ENSG00000172296 ENSG00000143418 PMC4009339__F3 Gene network of T-ALL (early response) derived from GeneMANIA (a) and STRING (b) (NR3C1 interaction is highlighted) ENSG00000004478 ENSG00000073614 ENSG00000113595 ENSG00000177606 ENSG00000145743 ENSG00000127948 PMC3678415__F2 HDL biogenesis ENSG00000160179 PMC3374768__F11 Activation of EGFR/ERBB2 via Pathways Involving ERK1/2, P38 MAPK, AKT and FOXO Enhances Recovery of Diabetic Hearts from Ischemia-Reperfusion Injury ENSG00000138798 ENSG00000146648 PMC6822566__F1 Complement cascade and its diverse effects of on alloimmunity and inflammation ENSG00000117335 ENSG00000166278 ENSG00000182326 PMC3678415__F1 HDL metabolic pathways and current drugs under development ENSG00000138075 ENSG00000130164 ENSG00000042832 ENSG00000100979 ENSG00000143921 PMC11820857__F10 In darkness (A), CRY1 remains in its inactive form and is unable to suppress BR signaling because it does not interact with dephosphorylated BES1 PMC9589344__F1 Targeting aldehyde dehydrogenase for prostate cancer therapies ENSG00000128917 ENSG00000168036 ENSG00000283100 PMC3221387__F1 Impact of miR-215 on cell proliferation, cell cycle, chemoresistance, and EMT ENSG00000228716 ENSG00000169554 ENSG00000143476 ENSG00000112118 PMC4061808__F4 Exercise activates a wide variety of intracellular signal transduction pathways to promote neurogenesis of granule cells from neuroprogenitors in the dentate gyrus ENSG00000134982 ENSG00000117707 PMC8405297__F6 Biological Activity, Hepatotoxicity, and Structure-Activity Relationship of Kavalactones and Flavokavins, the Two Main Bioactive Components in Kava (Piper methysticum) ENSG00000087245 ENSG00000135446 ENSG00000198793 ENSG00000100985 PMC10931536__F4 Selected epigenetic changes and host-virus interactions perpetrated by EBV nuclear antigens and latent membrane proteins ENSG00000095585 ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000173039 ENSG00000197943 ENSG00000162772 ENSG00000175104 ENSG00000168610 ENSG00000010671 PMC10525526__F1 Phenotype Alterations in the Cecal Ecosystem Involved in the Asymptomatic Intestinal Persistence of Paratyphoid Salmonella in Chickens ENSG00000169291 ENSG00000002330 ENSG00000175104 PMC7842006__F3 Ingenuity Pathway Analysis (IPA)-identified immune related gene networks with score > 20 ENSG00000136011 ENSG00000111537 ENSG00000105835 ENSG00000186716 ENSG00000169744 ENSG00000276798 ENSG00000170293 ENSG00000165238 PMC12145526__F2 The BMP pathway in the musculoskeletal system ENSG00000135655 ENSG00000170365 ENSG00000137834 ENSG00000103266 ENSG00000069869 ENSG00000198742 ENSG00000198793 ENSG00000120693 ENSG00000157450 PMC7783313__F5 Macrophage and bone remodeling related diseases ENSG00000275385 ENSG00000285379 PMC7490109__F1 Possible mechanism of SARS-CoV-2 mediated innate immune response at the lung alveolar cell ENSG00000108691 ENSG00000130234 ENSG00000125538 ENSG00000108700 ENSG00000175104 PMC12145526__F3 BMP signaling in OP ENSG00000178860 ENSG00000167772 ENSG00000108691 ENSG00000128272 ENSG00000159216 ENSG00000288335 ENSG00000108821 ENSG00000168646 PMC3338606__F6 Lipopolysaccharides Impair Insulin Gene Expression in Isolated Islets of Langerhans via Toll-Like Receptor-4 and NFKB Signalling ENSG00000172936 ENSG00000136869 ENSG00000182759 PMC12154924__F2 Recent Advances in Molecular Research and Treatment for Melanoma in Asian Populations ENSG00000157404 ENSG00000157764 ENSG00000198793 ENSG00000047936 PMC9167935__F9 MSC-ACE2 Ameliorates Streptococcus uberis-Induced Inflammatory Injury in Mammary Epithelial Cells by Upregulating the IL-10/STAT3/SOCS3 Pathway ENSG00000278718 ENSG00000162711 ENSG00000168610 PMC12145526__F7 Crosstalk of the BMP with other signaling pathways in musculoskeletal disorders (Created with BioRender ENSG00000162889 ENSG00000170365 ENSG00000137834 ENSG00000125398 ENSG00000159216 ENSG00000134982 ENSG00000168036 PMC9372960__F1 Deucravacitinib for the Treatment of Psoriatic Disease ENSG00000105397 ENSG00000105639 ENSG00000142224 PMC3171509__F1 This figure illustrates the core TSC-mTor pathway, as discussed in the text ENSG00000198793 PMC11006730__F4 Acid-sensing ion channels and downstream signalling in cancer cells: is there a mechanistic link? ENSG00000137275 ENSG00000285379 PMC2742584__F7 Interaction networks of As sensitivity in yeast ENSG00000204086 ENSG00000198554 ENSG00000163918 ENSG00000133119 PMC9381515__F3 Mechanism of necroptosis leads to airflow limitation in COPD ENSG00000189403 ENSG00000168404 ENSG00000285379 PMC8189177__F1 FGF10 and Lipofibroblasts in Lung Homeostasis and Disease: Insights Gained From the Adipocytes ENSG00000178860 ENSG00000066468 ENSG00000070193 ENSG00000111049 ENSG00000042832 ENSG00000134853 PMC4130217__F4 Protomural role of tumor-associated macrophages (TAM) ENSG00000275385 ENSG00000138798 ENSG00000168036 PMC8189177__F2 FGF10 and Lipofibroblasts in Lung Homeostasis and Disease: Insights Gained From the Adipocytes ENSG00000070193 ENSG00000168484 ENSG00000128342 PMC9381515__F1 Main detection methods of necroptosis ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC11544529__F2 DUBs in the PI3K/AKT, NFKB and MYC pathways in urologic cancers ENSG00000124422 ENSG00000291527 ENSG00000198793 ENSG00000116750 ENSG00000154914 ENSG00000083799 ENSG00000146648 ENSG00000140443 PMC11544529__F3 DUBs in the RAS/RAF/MEK/ERK, p53 and TGFB pathways in urologic cancers ENSG00000172046 ENSG00000048028 ENSG00000134588 PMC11544529__F4 DUBs in the Wnt/Beta-catenin and Hippo pathways in urologic cancers ENSG00000115464 ENSG00000134982 ENSG00000168036 ENSG00000143409 ENSG00000083799 ENSG00000150457 ENSG00000155313 ENSG00000131023 PMC7415419__F5 Models for mammalian target of rapamycin (mTOR) behaviors on autophagic signaling pathway activation during osteoclast differentiation and formation ENSG00000177169 ENSG00000198793 PMC4807884__F1 Regulation of SMN2 gene expression in SMA ENSG00000273772 ENSG00000113494 PMC7415419__F6 Autophagy regulatory signaling pathways are involved in the pathological process of osteoarthritis/rheumatoid arthritis (OA/RA) ENSG00000177169 ENSG00000198793 ENSG00000096717 ENSG00000142082 PMC5401738__F1 IL-12 activation of JAK-STAT pathway ENSG00000138378 ENSG00000105397 PMC10296674__F3 Canonical pathways derived using the IPA tool ENSG00000002330 ENSG00000046889 ENSG00000171791 ENSG00000160691 PMC3976829__F4 Schematic illustrations for potential signaling pathway of IMF deposition in skeletal muscles regulated by GHR and SOCS3 ENSG00000112964 ENSG00000136231 PMC11612504__F2 Role and mechanism of the EGFR/MET-mediated signaling pathway in cancer cells ENSG00000019991 ENSG00000002330 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC6664158__F1 Proposed molecular mechanisms of PAX3 in glioma pathogenesis and progression ENSG00000137673 ENSG00000135903 ENSG00000168036 ENSG00000131095 PMC4339542__F4A Interleukin 6 Alters Localization of hMSH3, Leading to DNA Mismatch Repair Defects in Colorectal Cancer Cells ENSG00000168610 PMC3677161__F5 Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease ENSG00000011600 ENSG00000030582 ENSG00000186517 ENSG00000216490 ENSG00000142347 ENSG00000158869 ENSG00000138964 ENSG00000163694 ENSG00000136286 ENSG00000171051 ENSG00000095585 ENSG00000150782 ENSG00000159216 ENSG00000103490 ENSG00000110446 ENSG00000095303 ENSG00000277263 ENSG00000131724 ENSG00000153551 ENSG00000086730 ENSG00000121552 ENSG00000091317 ENSG00000130208 ENSG00000119535 ENSG00000081237 ENSG00000162924 ENSG00000100060 ENSG00000110324 ENSG00000110719 ENSG00000019582 ENSG00000239998 ENSG00000163131 ENSG00000243646 ENSG00000028137 PMC10374212__F3 NLRP3: a new therapeutic target in alcoholic liver disease ENSG00000278718 ENSG00000125538 ENSG00000130649 ENSG00000172936 PMC3133616__F4 Functional network of ion channels in T lymphocytes ENSG00000092439 ENSG00000042832 ENSG00000167323 ENSG00000134982 ENSG00000293604 PMC8397987__F3 Fructose and Mannose in Inborn Errors of Metabolism and Cancer ENSG00000138030 ENSG00000136872 PMC7140408__F6 Reductive schematic of the proposed VPA induction pathway in the treatment of ADSCs toward neural differentiation ENSG00000171150 ENSG00000110244 ENSG00000105550 ENSG00000131095 ENSG00000146648 ENSG00000284468 PMC3169181__F2 Crosstalk between host autophagy and viruses ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC8298499__F6 Untargeted Metabolomic Profiling of Liver in a Chronic Intermittent Hypoxia Mouse Model ENSG00000168003 ENSG00000196839 ENSG00000167468 ENSG00000115107 PMC7826840__F4A Analysis of the Immune Responses in the Ileum of Gnotobiotic Pigs Infected with the Recombinant GII.p12_GII.3 Human Norovirus by mRNA Sequencing ENSG00000107485 ENSG00000162892 ENSG00000141968 PMC3921899__F1 Lipid signals and insulin resistance ENSG00000151726 ENSG00000198793 ENSG00000164327 ENSG00000062282 ENSG00000173599 ENSG00000150907 ENSG00000158669 ENSG00000285482 ENSG00000198670 ENSG00000026652 ENSG00000160216 ENSG00000186281 ENSG00000105723 PMC7897836__F2 Developmental Regulation of GFAP Expression ENSG00000099985 ENSG00000242689 ENSG00000126457 ENSG00000131095 ENSG00000128342 ENSG00000169375 ENSG00000162599 ENSG00000178568 PMC8929449__F5 Smoking-induced changes in buccal mucosal gene expression ENSG00000108443 ENSG00000118971 PMC8929449__F9 Smoking-induced changes in buccal mucosal gene expression ENSG00000100234 ENSG00000171105 ENSG00000101109 ENSG00000125651 ENSG00000269335 ENSG00000100227 ENSG00000000971 ENSG00000108443 ENSG00000006062 ENSG00000132693 ENSG00000144677 ENSG00000161681 ENSG00000177272 ENSG00000143801 ENSG00000040199 ENSG00000100784 ENSG00000128602 ENSG00000105204 PMC10036590__F4 Targeting CLDN18.2 in cancers of the gastrointestinal tract: New drugs and new indications ENSG00000066405 ENSG00000198793 PMC4942188__F1 Targeting lipid metabolism for the treatment of Anaplastic Thyroid Carcinoma ENSG00000135218 ENSG00000130164 ENSG00000138798 ENSG00000198793 ENSG00000113161 ENSG00000169710 ENSG00000099194 PMC8834417__F1 Influence of the Metabolism on Myeloid Cell Functions in Cancers: Clinical Perspectives ENSG00000198793 ENSG00000159399 PMC3470584__F2 Suppressed RNA-Polymerase 1 Pathway Is Associated with Benign Multiple Sclerosis ENSG00000180182 ENSG00000182899 ENSG00000056972 ENSG00000232326 ENSG00000087085 ENSG00000091409 ENSG00000087303 ENSG00000072364 ENSG00000278494 ENSG00000276618 ENSG00000159216 ENSG00000121068 ENSG00000171456 ENSG00000133878 ENSG00000263528 ENSG00000136997 ENSG00000105825 ENSG00000139193 ENSG00000065357 ENSG00000142627 ENSG00000152495 ENSG00000138495 ENSG00000167658 ENSG00000164120 ENSG00000136213 ENSG00000149311 ENSG00000186184 ENSG00000111537 ENSG00000163430 ENSG00000143507 ENSG00000026508 ENSG00000054118 ENSG00000175104 ENSG00000131196 ENSG00000127616 PMC9461676__F3 Tumor Microenvironment and its Implications for Antitumor Immunity in Cholangiocarcinoma: Future Perspectives for Novel Therapies ENSG00000170962 ENSG00000137033 ENSG00000112715 ENSG00000078098 ENSG00000150630 PMC9461676__F4 Tumor Microenvironment and its Implications for Antitumor Immunity in Cholangiocarcinoma: Future Perspectives for Novel Therapies ENSG00000115271 ENSG00000049768 ENSG00000026103 ENSG00000277335 PMC5714444__F1 Intracellular sugar-responsive gene regulatory network ENSG00000160584 ENSG00000096717 PMC5714444__F2 The role of the HBP and protein O-linked GlcNAc conjugation in the regulation of Drosophila physiology ENSG00000147162 ENSG00000198408 ENSG00000013375 PMC7826431__F3 Open questions regarding NB–MSC interactions ENSG00000168610 ENSG00000140443 PMC3932028__F5 Rapgef2 Connects GPCR-Mediated cAMP Signals to ERK Activation in Neuronal and Endocrine Cells ENSG00000109756 PMC8582349__F3 MicroRNAs: Important Players in Breast Cancer Angiogenesis and Therapeutic Targets ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC6985587__F2 Predicted interactions among apoplastic proteins and signaling molecules in resurrection plants during dehydration PMC4222910__F6 In Vitro, In Silico and In Vivo Studies of Ursolic Acid as an Anti-Filarial Agent ENSG00000135218 ENSG00000170458 ENSG00000172005 ENSG00000150455 ENSG00000184216 PMC9461676__F5 Tumor Microenvironment and its Implications for Antitumor Immunity in Cholangiocarcinoma: Future Perspectives for Novel Therapies ENSG00000099985 ENSG00000163739 ENSG00000168610 PMC8107678__F1 Toll-Like Receptors Gene Polymorphisms in Autoimmune Disease ENSG00000172936 ENSG00000150455 ENSG00000175104 PMC8431455__F5 Hexokinase and Hexose Transporters in Preferential Use of Glucose over Fructose and Downstream Metabolic Pathways in the Yeast Yarrowia lipolytica ENSG00000146701 PMC7955431__F1 Coronavirus Disease 2019–Associated Thrombosis and Coagulopathy: Review of the Pathophysiological Characteristics and Implications for Antithrombotic Management ENSG00000150782 ENSG00000130234 ENSG00000184012 ENSG00000148175 ENSG00000122194 PMC9147390__F9 Evaluation of TILI-2 as an Anti-Tyrosinase, Anti-Oxidative Agent and Its Role in Preventing Melanogenesis Using a Proteomics Approach ENSG00000121989 ENSG00000132906 ENSG00000135776 ENSG00000006712 ENSG00000198742 ENSG00000135903 ENSG00000188130 ENSG00000107165 ENSG00000121879 ENSG00000171608 ENSG00000135341 PMC4794363__F6 SGEF is Regulated via TWEAK/Fn14/NFKB Signaling and Promotes Survival by Modulation of the DNA Repair Response to Temozolomide ENSG00000012048 ENSG00000127191 PMC2921475__F1 Cord Blood Genomic Analysis Highlights the Role of Redox Balance ENSG00000175567 PMC12092457__F1 SPC25 is an important part of the NDC80 centromere complex ENSG00000277909 ENSG00000143228 PMC23119__F3 Roles of INH-induced genes in the context of a proposed pathway for mycolic acid biosynthesis ENSG00000123999 ENSG00000062485 PMC6794807__F5 Protein-Protein interaction network and 5 identified sub-networks of TTR-mRNAs ENSG00000110514 ENSG00000135473 ENSG00000148926 ENSG00000173039 ENSG00000084110 ENSG00000160710 ENSG00000120885 ENSG00000070669 ENSG00000115317 ENSG00000100473 ENSG00000119397 ENSG00000058453 ENSG00000100294 ENSG00000127948 ENSG00000164949 PMC8775450__F2 Sirtuins Modulation: A Promising Strategy for HIV-Associated Neurocognitive Impairments ENSG00000128272 ENSG00000196839 ENSG00000158828 ENSG00000096717 ENSG00000142082 ENSG00000283100 ENSG00000106459 PMC8359037__F2 Systematic summary of survival and death signalling during the life of hair follicle stem cells ENSG00000134982 ENSG00000168036 PMC7590459__F1 Simplified diagram of the KP PMC6539070__F2 Molecular mechanisms of adipogenesis ENSG00000168036 ENSG00000102935 PMC8359037__F3 Systematic summary of survival and death signalling during the life of hair follicle stem cells ENSG00000164690 ENSG00000128602 PMC4064254__F2 An atlas of genetic influences on human blood metabolites ENSG00000146281 ENSG00000135423 ENSG00000140386 ENSG00000148832 ENSG00000095321 ENSG00000137198 ENSG00000103222 ENSG00000257335 ENSG00000099194 ENSG00000156150 ENSG00000100033 ENSG00000197208 ENSG00000146733 ENSG00000095906 ENSG00000108839 ENSG00000178814 ENSG00000154122 ENSG00000092621 ENSG00000149485 ENSG00000084734 ENSG00000172482 ENSG00000171759 ENSG00000147576 PMC3001953__F2 EGFR-mutated lung cancer: a paradigm of molecular oncology ENSG00000120875 ENSG00000291431 ENSG00000198793 PMC4937026__F4 Activation of STAT3 in KSHV-infected endothelial cells ENSG00000185437 ENSG00000196352 ENSG00000168610 PMC8724243__F1 Progress on the Function and Application of Thymosin B4 ENSG00000138795 ENSG00000168036 PMC6794807__F9 Five functional lncRNA-mRNA trans regulatory network ENSG00000111596 ENSG00000131778 ENSG00000070669 ENSG00000102977 PMC8044749__F1 Proposed immunopathological roles of circulating histones in sepsis PMC9010858__F2 Treatment of Retinoblastoma: What Is the Latest and What Is the Future PMC11024162__F9 TGFB signaling pathway PMC3460040__F8 Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with Sorafenib ENSG00000157764 ENSG00000167323 ENSG00000293604 PMC3773516__F6 MEF2C Haploinsufficiency features consistent hyperkinesis, variable epilepsy, and has a role in dorsal and ventral neuronal developmental pathways ENSG00000169554 ENSG00000136535 ENSG00000102081 ENSG00000081189 ENSG00000004848 PMC3601842__F1 mTOR: a link from the extracellular milieu to transcriptional regulation of oligodendrocyte development ENSG00000198793 ENSG00000155792 ENSG00000164327 PMC12018393__F4 Tamoxifen metabolic pathway PMC8359037__F7 Systematic summary of survival and death signalling during the life of hair follicle stem cells ENSG00000132906 ENSG00000168040 ENSG00000164305 PMC12018393__F8 Fulvestrant predominant metabolic pathway ENSG00000196502 ENSG00000244474 PMC9448512__F1 Canonical and non-canonical AhR signaling pathways ENSG00000103257 ENSG00000140465 ENSG00000106546 PMC3670316__F7 Dynamic CREB family activity drives segmentation and posterior polarity specification in mammalian somitogenesis ENSG00000154342 ENSG00000203877 ENSG00000188095 ENSG00000149922 PMC12018393__F6 Toremifene metabolic pathway PMC4260983__F1 Sex hormone biosynthesis and degradation pathway ENSG00000277893 ENSG00000140465 ENSG00000203857 PMC12092457__F2 SPC25 can be used as a scaffolding platform to coordinate the assembly of the SPC25/RIOK1/MYH9 trimer complex, triggering RIOK1-mediated phosphorylation of MYH9 Ser1943 ENSG00000124784 ENSG00000277909 ENSG00000100345 PMC5228523__F4 MicroRNA-gene interaction networks of the MAPK signaling pathway ENSG00000117525 ENSG00000011566 ENSG00000119487 ENSG00000186716 ENSG00000205089 ENSG00000213341 ENSG00000069956 ENSG00000169032 ENSG00000099942 ENSG00000282899 ENSG00000158050 ENSG00000026103 PMC7772402__F1 Schematic presentation of early steps of SARS-CoV-2 life cycle ENSG00000090402 ENSG00000130234 ENSG00000184012 PMC4728678__F2 Lipid rafts as platforms for cell signaling ENSG00000291971 ENSG00000168040 ENSG00000121966 PMC125938__F8 An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype ENSG00000117707 ENSG00000174059 PMC5138100__F6 New Insights into Protein Hydroxylation and Its Important Role in Human Diseases ENSG00000187266 ENSG00000069956 ENSG00000086758 PMC4075164__F2 Multiple intracellular signal transduction pathways are activated by GH ENSG00000112964 ENSG00000291971 PMC4194224__F7 Expression of Suppressor of Cytokine Signaling-3 (SOCS3) and its role in neuronal death after complete spinal cord injury ENSG00000168610 PMC7198187__F1 Immunomodulation in COVID-19 ENSG00000108691 ENSG00000213928 ENSG00000115415 ENSG00000181847 ENSG00000130234 ENSG00000137265 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC4235760__F1 MICRORNAs IN ER STRESS: DIVERGENT ROLES IN CELL FATE DECISIONS ENSG00000128272 ENSG00000144895 ENSG00000265972 PMC5968394__F2 PI3K/Akt signaling facilitates ROS detoxification and redox homeostasis ENSG00000118515 ENSG00000079999 PMC2785932__F3 Four pathways by which the EBV latent membrane protein 1 (LMP1) is thought to signal inside cells ENSG00000102871 ENSG00000084734 ENSG00000056558 ENSG00000131323 ENSG00000105639 ENSG00000127191 PMC2383880__F7 A logic-based diagram of signalling pathways central to macrophage activation ENSG00000160789 ENSG00000077150 ENSG00000196954 ENSG00000173039 ENSG00000026103 PMC2383880__F1 Manual layout of Type II interferon signalling (IFNG) taken from the integrated pathway diagram (Figure 2) ENSG00000150782 ENSG00000180447 ENSG00000111537 PMC4914733__F7 Proposed signaling mechanisms mediated by Lipoxin A4 in preventing intestinal epithelium cells from intestine ischemia reperfusion (IIR) injury ENSG00000145384 ENSG00000079999 PMC6546329__F3 Intestinal luminal putrescine is produced by collective biosynthetic pathways of the commensal microbiome ENSG00000036473 PMC3711139__F4 Preparation of Dihydrothieno- and Dihydrofuranopyrimidines ENSG00000144857 PMC10815168__F1 Schematic diagram depicting the miRNA signaling pathways activated by aldosterone through the MR ENSG00000100234 ENSG00000066044 ENSG00000060237 ENSG00000118515 ENSG00000253352 ENSG00000176387 PMC6370674__F2 Pathway map of Notch signaling (A) and Th1 differentiation (B) in KEGG ENSG00000138378 ENSG00000087085 ENSG00000120885 PMC6598836__F4 Essential metabolism and mitochondrial regulation on B cells (A) and Antibody-Secreting Cells (B) ENSG00000186716 ENSG00000010278 ENSG00000026103 PMC7699985__F1 VEGFR-2 signaling and 4 types of anti-angiogenic agents ENSG00000291971 ENSG00000112715 PMC8779539__F1 Impaired Folate-Mediated One-Carbon Metabolism in Type 2 Diabetes, Late-Onset Alzheimer’s Disease and Long COVID PMC5568615__F2 COX-2/PGE2pathway in colitis-associated CRC ENSG00000163739 PMC7335982__F6 Signaling pathways and deregulation of its modalities such as Stat3/mTor, Hedgehog, Notch and Wnt/-catenin cascade defined as a new therapeutic strategy in the prevention of cancer extension, especially CSCs growth behaviors modification () ENSG00000134982 ENSG00000168036 ENSG00000128602 PMC9366743__F6 Beta-Carboline Alkaloids From the Deep-Sea Fungus Trichoderma sp. MCCC 3A01244 as a New Type of Anti-pulmonary Fibrosis Agent That Inhibits TGFB/Smad Signaling Pathway PMC12039932__F5 Nanomaterial-based DDSs treat OA by targeting chondrocytes ENSG00000154342 ENSG00000171791 PMC9288068__F4 Exploring immunotherapy in colorectal cancer ENSG00000169248 ENSG00000169245 ENSG00000101751 ENSG00000115415 ENSG00000138755 PMC12039932__F3 Nanomaterial-based DDSs treat OA by targeting synoviocytes ENSG00000104321 ENSG00000149968 ENSG00000198793 PMC3215775__F1 Molecular mechanisms through the Epidermal Growth Factor Receptor pathway ENSG00000138798 ENSG00000146648 PMC6487669__F16 De Novo Pyrimidine Biosynthetic Pathway Diagram ENSG00000134326 ENSG00000047230 ENSG00000102967 ENSG00000084774 PMC12039932__F2 Nanomaterial-based DDSs treat OA by targeting macrophages ENSG00000164430 ENSG00000198793 ENSG00000196689 ENSG00000164342 PMC8085542__F1 Nuclear hormone and peptide hormone therapeutics for NAFLD and NASH ENSG00000159224 ENSG00000130164 ENSG00000291972 ENSG00000112964 ENSG00000288269 ENSG00000160867 ENSG00000105550 ENSG00000167910 ENSG00000010310 PMC7105304__F10 Leptin-mediated MTP regulation through long- (ObRb) and short- (ObRa) forms of leptin receptors ENSG00000168610 PMC10749620__F2 NRF2 peptide with its seven Neh domains and their roles ENSG00000178573 ENSG00000100387 ENSG00000079999 PMC10749620__F3 KEAP1-NRF2-ARE pathway ENSG00000178573 ENSG00000100387 ENSG00000079999 PMC10749620__F4 KEAP1-NRF2 by P62 non-canonical pathway ENSG00000100387 ENSG00000079999 PMC7823450__F1 Metabolic pathway of oxysterol sulfates ENSG00000138135 ENSG00000036530 ENSG00000135929 PMC7823450__F2 Novel regulatory pathway of oxysterol sulfation ENSG00000002330 ENSG00000135929 PMC6341466__F1 Expanding the Clinical and Molecular Characteristics of PIGT-CDG, a Disorder of Glycosylphosphatidylinositol Anchors ENSG00000069943 ENSG00000135845 ENSG00000100564 ENSG00000197563 ENSG00000185808 ENSG00000255072 ENSG00000197121 ENSG00000165282 ENSG00000275600 ENSG00000142892 ENSG00000143315 ENSG00000161395 ENSG00000163964 ENSG00000108474 ENSG00000060642 ENSG00000101464 ENSG00000124155 ENSG00000148985 ENSG00000197858 ENSG00000136908 PMC10948547__F1 Molecular mechanisms of TLR4 in osteoporosis development ENSG00000066135 ENSG00000189403 ENSG00000139842 ENSG00000172936 ENSG00000136869 PMC3273847__F1 Innate Immunity in the Host Defense Against intestinal Bacterial Pathogens ENSG00000167207 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000106100 ENSG00000276561 ENSG00000164342 PMC8391638__F2 Rho-Proteins and Downstream Pathways as Potential Targets in Sepsis and Septic Shock: What Have We Learned from Basic Research ENSG00000163914 PMC6398501__F8 An integrated model for ROS mediated clearance of VAP(P58S) aggregates via UPS ENSG00000198793 ENSG00000165280 PMC4905335__F1 Mechanism of retention of BRCA1/BARD1 complexes at DNA double-strand break sites ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000163961 ENSG00000080345 ENSG00000116731 ENSG00000113648 ENSG00000112130 PMC6329923__F8 Proposed model of the mechanism of GALNT6-mediated regulation of proliferation and metastasis thought Beta-catenin /MUC1-C signaling in breast cancer ENSG00000134982 ENSG00000139629 ENSG00000168036 PMC5104508__F1 Classical view of progressive linear cascades in the asymmetry-determining pathway ENSG00000170365 ENSG00000156574 ENSG00000164093 ENSG00000164690 PMC7915278__F5 Selected network of 138 proteins that were found in a functional screen for proteins involved in the pathway in cancer (KEGG: hsa05200) ENSG00000004975 ENSG00000047410 ENSG00000157404 ENSG00000070831 ENSG00000105329 ENSG00000044115 ENSG00000198793 ENSG00000196591 ENSG00000168036 ENSG00000150093 ENSG00000091409 ENSG00000105647 ENSG00000171791 ENSG00000169032 ENSG00000099942 ENSG00000100485 ENSG00000121879 ENSG00000164305 ENSG00000053747 ENSG00000077150 ENSG00000066336 ENSG00000113318 ENSG00000056558 ENSG00000197943 ENSG00000124181 ENSG00000140464 ENSG00000140443 ENSG00000132906 ENSG00000162552 ENSG00000023445 ENSG00000104365 ENSG00000005339 ENSG00000101109 ENSG00000033800 ENSG00000269335 ENSG00000213341 ENSG00000127191 ENSG00000017797 ENSG00000110395 ENSG00000100387 ENSG00000186716 ENSG00000006451 ENSG00000144118 ENSG00000100985 ENSG00000161202 ENSG00000095002 PMC4979485__F1 LINP1 regulation and role in the NHEJ DNA-repair pathway ENSG00000188486 ENSG00000149311 ENSG00000146648 PMC7915278__F4 Functional networks of proteins involved in the following pathways: (A) B-cell receptor (BCR) signaling pathway (hsa04662), (B) cellular adhesion molecules (CAMs) pathway (hsa04514), (C) PPAR signaling pathway (hsa03320) ENSG00000070190 ENSG00000151726 ENSG00000282905 ENSG00000134215 ENSG00000091409 ENSG00000100485 ENSG00000095585 ENSG00000177455 ENSG00000157184 ENSG00000018236 ENSG00000188404 ENSG00000100979 ENSG00000277263 ENSG00000140284 ENSG00000160293 ENSG00000123983 ENSG00000198910 ENSG00000135929 ENSG00000088827 ENSG00000197471 ENSG00000213341 ENSG00000152689 ENSG00000292348 ENSG00000261371 ENSG00000224320 ENSG00000179344 ENSG00000162692 ENSG00000187446 ENSG00000087008 ENSG00000115904 ENSG00000149294 ENSG00000110651 ENSG00000150093 ENSG00000105647 ENSG00000169032 ENSG00000121879 ENSG00000141968 ENSG00000010671 ENSG00000117054 ENSG00000116815 ENSG00000076662 ENSG00000113790 ENSG00000139626 ENSG00000104365 ENSG00000105369 ENSG00000169896 ENSG00000090863 ENSG00000100906 ENSG00000167114 ENSG00000081237 ENSG00000109320 ENSG00000007312 ENSG00000269335 ENSG00000173039 ENSG00000117322 ENSG00000099866 ENSG00000120910 ENSG00000130304 ENSG00000281614 ENSG00000161533 ENSG00000197142 ENSG00000164398 ENSG00000171608 ENSG00000115232 ENSG00000131196 PMC4841712__F1 Regain control of p53: targeting leukemia stem cells by isoform-specific HDAC inhibition ENSG00000149311 ENSG00000124422 ENSG00000147099 ENSG00000137193 ENSG00000096717 PMC5435887__F1 Main genetic and signaling pathway alterations in UMs and CMs ENSG00000038382 ENSG00000163930 ENSG00000157404 ENSG00000157764 ENSG00000046889 ENSG00000198793 ENSG00000163914 ENSG00000165527 ENSG00000155903 ENSG00000101333 ENSG00000196712 PMC11155398__F4 Biological functions of SUMOylation cascade in tumors ENSG00000145388 ENSG00000132109 ENSG00000118518 ENSG00000142230 ENSG00000198492 ENSG00000116030 ENSG00000146457 ENSG00000125347 ENSG00000184900 ENSG00000165819 ENSG00000130726 PMC2670969__F4 PBT-1 induced genes in different pathways according to the KEGG and BIOCARTA pathway databases ENSG00000002330 ENSG00000112964 ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 ENSG00000277273 ENSG00000134480 PMC7166496__F5 Regional signaling pathway analysis of the genes associated with heart diseases ENSG00000143149 ENSG00000073578 ENSG00000138029 ENSG00000091140 ENSG00000062485 PMC6559935__F1 Leptin and leptin receptor activation pathway ENSG00000168610 PMC11155398__F2 Biological significance manipulated by SUMOylation in tumors ENSG00000079387 ENSG00000118518 ENSG00000163961 ENSG00000033800 ENSG00000073792 ENSG00000141568 ENSG00000101266 ENSG00000116030 ENSG00000133422 ENSG00000184900 ENSG00000130726 PMC5866057__F1 MTOR signaling pathway with potential contributions from GABA and Glu receptors ENSG00000159224 ENSG00000135932 ENSG00000171791 ENSG00000100033 ENSG00000112715 ENSG00000062485 PMC3967868__F1 Drug resistance mediated by AEG-1/MTDH/LYRIC ENSG00000188641 ENSG00000147649 ENSG00000150907 ENSG00000136997 ENSG00000100985 ENSG00000057663 ENSG00000123908 PMC5983605__F2 Diagram of WNT (Wingless-type) signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC2811646__F4 Molecular targets in NFKB pathway modulated by PEITC and SFN ENSG00000175793 PMC2811646__F3 Molecular targets in Nrf2/phase II enzymes pathway modulated by PEITC and SFN ENSG00000175793 ENSG00000178573 ENSG00000079999 PMC8068835__F11 Summarized interconnection between PC synthesis, trans-sulfuration pathway, folate cycle, methionine cycle, polyamine pathway, and trypanothion synthesis ENSG00000173599 ENSG00000133027 PMC9251307__F1 Molecular Mechanism of Caffeine in Preventing Bronchopulmonary Dysplasia in Premature Infants ENSG00000128272 ENSG00000079999 PMC4817351__F8 Molecular pathways of proliferation, survival and senescence ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 ENSG00000047936 PMC8788178__F2 Multiple roles of mothers against decapentaplegic homolog 4 in tumorigenesis, stem cells, drug resistance, and cancer therapy ENSG00000170365 ENSG00000137834 PMC11835119__F4 Phyllanthus emblica–active components–target–pathway network ENSG00000145864 ENSG00000103222 ENSG00000106688 ENSG00000069667 ENSG00000112038 ENSG00000151834 ENSG00000077782 ENSG00000276996 ENSG00000157542 ENSG00000142192 ENSG00000162551 ENSG00000116329 ENSG00000101180 ENSG00000169432 ENSG00000126012 ENSG00000061938 ENSG00000117480 ENSG00000074410 ENSG00000140505 ENSG00000198793 ENSG00000087085 ENSG00000070610 ENSG00000101266 ENSG00000169032 ENSG00000112715 ENSG00000121879 ENSG00000164305 ENSG00000118777 ENSG00000274542 ENSG00000164879 ENSG00000133019 ENSG00000178607 ENSG00000165841 ENSG00000129214 ENSG00000215301 ENSG00000179546 ENSG00000080644 ENSG00000171189 ENSG00000168748 ENSG00000011677 ENSG00000147432 ENSG00000144285 ENSG00000150594 ENSG00000169427 ENSG00000157540 ENSG00000171234 ENSG00000157764 ENSG00000108861 ENSG00000169239 ENSG00000147434 ENSG00000174990 ENSG00000145863 ENSG00000124493 ENSG00000164082 ENSG00000036828 ENSG00000073756 ENSG00000168610 ENSG00000274286 ENSG00000176884 ENSG00000156110 ENSG00000113327 ENSG00000100985 ENSG00000196689 PMC3443126__F7 H2O2-modulated permeability increase and cytoskeleton reorganization via MARCKS phosphorylation in endothelial cells ENSG00000124181 PMC6540205__F3 Activation of the prolactin signalling pathway in the mink uterus in activated versus diapause states PMC8126061__SF1 Iridin Induces G2/M Phase Cell Cycle Arrest and Extrinsic Apoptotic Cell Death through PI3K/AKT Signaling Pathway in AGS Gastric Cancer Cells ENSG00000134057 ENSG00000026103 PMC11835119__F7 Exploring the mechanism of action of Phyllanthus emblica in the treatment of epilepsy based on network pharmacology and molecular docking ENSG00000152266 ENSG00000159224 ENSG00000112964 ENSG00000174417 ENSG00000160013 ENSG00000248329 ENSG00000102539 ENSG00000181408 ENSG00000170498 ENSG00000157017 ENSG00000188710 ENSG00000075073 ENSG00000285456 ENSG00000010310 ENSG00000169836 ENSG00000183395 ENSG00000096395 ENSG00000004948 ENSG00000165409 ENSG00000170893 ENSG00000198670 ENSG00000121853 ENSG00000134548 ENSG00000128564 PMC6540205__F1 Activation of the PI3K/AKT signalling pathway in mink uteri in activated versus diapause states ENSG00000177455 ENSG00000012048 ENSG00000065833 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000136997 ENSG00000152430 PMC8600110__F1 Receptor-Mediated NETosis on Neutrophils ENSG00000163464 ENSG00000162711 ENSG00000239732 ENSG00000167207 ENSG00000130234 ENSG00000184012 ENSG00000189403 ENSG00000136869 ENSG00000005381 PMC5445935__F2 Correlates of metastatic melanoma response to checkpoint inhibition ENSG00000163599 ENSG00000273686 PMC8711145__F6 Spotlight on NLRP3 Inflammasome: Role in Pathogenesis and Therapies of Atherosclerosis ENSG00000162711 ENSG00000137275 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000168040 PMC3372530__F2 Diagram of genes that have been implicated in susceptibility to CL and ML disease caused by L ENSG00000151702 ENSG00000185591 ENSG00000168610 PMC8711145__F2 Spotlight on NLRP3 Inflammasome: Role in Pathogenesis and Therapies of Atherosclerosis ENSG00000278718 ENSG00000162711 ENSG00000088888 ENSG00000167207 ENSG00000134326 ENSG00000265972 ENSG00000036828 ENSG00000173612 PMC6574129__F5 Aurora kinase plus BTK blockade inhibits the chronic active BCR pathway and induces apoptosis in DH/DE-DLBCL ENSG00000197943 PMC3291789__F1 Targeting the p53 signaling pathway in cancer therapy - The promises, challenges, and perils ENSG00000116717 ENSG00000158169 ENSG00000285069 ENSG00000080546 ENSG00000134574 ENSG00000164938 ENSG00000112378 ENSG00000128342 ENSG00000078237 ENSG00000284194 ENSG00000095002 ENSG00000026103 ENSG00000198625 PMC9409103__F3 Recent Developments in the Understanding of Immunity, Pathogenesis and Management of COVID-19 ENSG00000183735 ENSG00000164430 PMC5140782__F1 Metabolic rewiring in melanoma ENSG00000284320 ENSG00000228716 ENSG00000125166 ENSG00000143158 ENSG00000172840 ENSG00000092621 ENSG00000136997 ENSG00000124253 ENSG00000166123 ENSG00000070669 ENSG00000115419 ENSG00000060762 PMC11948033__F3 Modulation effect of TEVs on CD8+ T cell ENSG00000168283 ENSG00000147162 ENSG00000276051 ENSG00000026103 PMC5140782__F2 Metabolic rewiring in melanoma ENSG00000157764 ENSG00000196712 ENSG00000117305 PMC11948033__F4 Treatment strategies to reversing immune escape ENSG00000119888 PMC7013084__F1 CSCs alter the composition and functional properties of immune cell subsets, which results in an impaired CSC recognition and elimination by the immune system ENSG00000108691 ENSG00000198053 ENSG00000049768 PMC9686704__F1 Research Progress on Mitochondrial Dysfunction in Diabetic Retinopathy PMC3501207__F1 Cholesterol Accumulation Regulates the Expression of Macrophage Proteins Implicated In Proteolysis and Complement Activation ENSG00000180210 ENSG00000173369 ENSG00000169896 ENSG00000173372 ENSG00000118785 ENSG00000170458 ENSG00000000971 ENSG00000136689 PMC9258520__F1 Cancer treatment-induced NAD+ depletion in premature senescence and late cardiovascular complications ENSG00000187531 ENSG00000105835 ENSG00000180773 ENSG00000123572 ENSG00000221955 ENSG00000278488 ENSG00000146477 ENSG00000262217 ENSG00000077463 ENSG00000103257 ENSG00000142082 ENSG00000283100 ENSG00000157064 ENSG00000124523 ENSG00000173614 ENSG00000122696 ENSG00000008130 ENSG00000096717 ENSG00000089163 PMC4964437__F2 Lipid mediators and HIF1A signaling in hypoxic prostate cancer (PCa) cells ENSG00000291971 PMC4494663__F14 New Biology of Estrogen-induced Apoptosis Applied to Treat and Prevent Breast Cancer ENSG00000171791 ENSG00000168040 PMC4604214__F3 Key Figure: Developmental and Disease-associated Pathways Regulated by Chromodomain Helicase DNA Binding Protein 7 (CHD7).CHD7 can affect the activity of several signalling pathways that control development ENSG00000070193 ENSG00000170365 ENSG00000106571 ENSG00000168505 ENSG00000075213 PMC11742855__F4 Сomplex interplay between cell cycle-related genes and their influence on various signaling pathways in NETs ENSG00000119888 ENSG00000135446 ENSG00000198793 ENSG00000164327 ENSG00000171791 ENSG00000146648 PMC11280205__F5 Mechanism in the development of a higher 2D:4D ratio ENSG00000074181 PMC5855762__F1 The molecular signaling pathways underlying the effects of CC2238/AANP in endothelial cells, smooth muscle cells, and platelets ENSG00000159224 ENSG00000069482 PMC7693470__F1 Schematic simplified representation of thyroid hormone synthesis ENSG00000042832 ENSG00000176153 PMC8564336__F1 Biological and clinical implications of metastasis‐associated circular RNAs in oesophageal squamous cell carcinoma ENSG00000170558 ENSG00000168036 ENSG00000277641 PMC11506032__F5 Pathophysiology, Treatment, and Prognosis of Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis/Renal Failure, and Organomegaly (TAFRO) Syndrome: A Review ENSG00000115415 ENSG00000198793 ENSG00000112715 ENSG00000168610 PMC8016949__F1 Assessing fatty acid-induced lipotoxicity and its therapeutic potential in glioblastoma using stimulated Raman microscopy ENSG00000285482 ENSG00000062282 ENSG00000026103 PMC5214845__F3 Role of microglia in ischemic focal stroke and recovery: focus on Toll-like receptors ENSG00000172005 ENSG00000172936 ENSG00000175104 PMC3428377__F3 Signaling pathways for estrogen production and action ENSG00000124102 ENSG00000130522 ENSG00000177606 PMC4522054__F1 Conceptual model of general health factors, salient CHD pathogenetic pathways and CHD hallmarks ENSG00000162692 ENSG00000005381 ENSG00000132693 PMC8015649__F3 Mitochondrial Pyruvate Carriers are Required for Myocardial Stress Adaptation ENSG00000147162 ENSG00000198408 ENSG00000092621 ENSG00000173599 PMC3706484__F5 Xenogeneic-Free Protocol for Isolation and Expansion of Human Adipose Stem Cells for Clinical Uses ENSG00000113070 ENSG00000115590 ENSG00000124491 ENSG00000273686 ENSG00000110324 ENSG00000187266 ENSG00000132185 ENSG00000092820 PMC11980100__F9 Histone acetyltransferase CBP participates in regulating the DNA damage response through ATM after double-strand breaks ENSG00000188486 ENSG00000149311 PMC2913378__F3 Signaling pathways that mediate actomyosin-dependent disruption of the epithelial barrier in inflammation ENSG00000111537 ENSG00000125538 ENSG00000163914 PMC8038106__F1 Molecular pathophysiology of hereditary hemorrhagic telangiectasia (HHT) ENSG00000171759 ENSG00000204217 PMC8469305__F5 Methyl Brevifolincarboxylate Attenuates Free Fatty Acid-Induced Lipid Metabolism and Inflammation in Hepatocytes through AMPK/NFKB Signaling Pathway ENSG00000042832 ENSG00000125538 ENSG00000169710 PMC8375232__F4 Functional roles, cross-talk and clinical implications of m6A modification and circRNA in hepatocellular carcinoma ENSG00000198492 ENSG00000107581 PMC12084965__F7 Green tea epigallocatechin gallate attenuate metabolic dysfunction-associated steatotic liver disease by regulation of pyroptosis ENSG00000278718 ENSG00000162711 ENSG00000069482 PMC8375232__F5 Functional roles, cross-talk and clinical implications of m6A modification and circRNA in hepatocellular carcinoma ENSG00000168036 ENSG00000134245 PMC8004548__F1 Interleukin-6 classical and trans-signaling ENSG00000120833 ENSG00000137845 PMC6220136__F1 EGFR signaling and generation of Treg and tol-DC ENSG00000109321 ENSG00000138798 ENSG00000049768 ENSG00000168610 ENSG00000146648 PMC7230049__F1 Rationale for homocysteine removal by the administration of a full array of activated micronutrients ENSG00000228716 ENSG00000205221 ENSG00000124275 ENSG00000016391 ENSG00000116984 PMC3816537__F3 Pathway based analysis of high ranking composite score genes reveals key signaling pathways associated with PDAC clinical progression ENSG00000110395 ENSG00000291971 ENSG00000198793 ENSG00000168040 ENSG00000146648 ENSG00000164305 ENSG00000026103 ENSG00000160049 PMC4080280__F4 Stage-specific expression of individual genes in Ras and Wnt pathway orchestrate cardiogenesis ENSG00000107779 ENSG00000124102 ENSG00000281324 ENSG00000187682 ENSG00000134982 ENSG00000138798 ENSG00000269335 ENSG00000141639 ENSG00000167074 ENSG00000168036 ENSG00000138071 ENSG00000069956 ENSG00000166484 ENSG00000137764 ENSG00000168610 ENSG00000179295 ENSG00000170365 ENSG00000167941 ENSG00000177606 ENSG00000188130 ENSG00000128342 ENSG00000171608 ENSG00000204217 PMC8038106__F2 Targets of bevacizumab and tacrolimus ENSG00000170365 ENSG00000204217 PMC8456159__F7 Altered regulation of DPF3, a member of the SWI/SNF complexes, underlies the 14q24 renal cancer susceptibility locus ENSG00000162594 ENSG00000103888 ENSG00000168610 ENSG00000205683 PMC3225503__F6 Pathway model based on vision related TMT-associated gene expression changes indicating a possible mechanism for TMT elicited neurobehavioral changes ENSG00000120500 ENSG00000105392 ENSG00000163914 PMC6451295__F3 Different sources of EVs in the cancer-to-stroma communication network ENSG00000198053 ENSG00000135404 ENSG00000146648 PMC5140782__F3 Metabolic rewiring in melanoma ENSG00000167468 PMC8529160__F4 Neuroinflammatory Triangle Presenting Novel Pharmacological Targets for Ischemic Brain Injury ENSG00000111837 ENSG00000137845 PMC4973254__F5 Predictive Immunohistochemical Markers Related to Drug Selection for Patients Treated with Sunitinib or Sorafenib for Metastatic Renal Cell Cancer ENSG00000134086 PMC4882277__F7 Proposed mechanism by which miR-21 links hepatic lipid accumulation and the development of cancer ENSG00000134057 PMC3410018__F5 Immune cell types implied to be involved in celiac disease by pathway analyses ENSG00000111537 ENSG00000134982 ENSG00000163599 ENSG00000183625 ENSG00000125538 ENSG00000160223 ENSG00000168610 ENSG00000115607 ENSG00000026103 PMC7339077__F2 Biomarkers of primary and acquired resistance occurring in the (A) tumor microenvironment (TME), (B) in the tumor, and (C) host factors ENSG00000089692 ENSG00000181847 ENSG00000168036 ENSG00000273686 PMC4899229__F1 Type III IFN signaling pathway ENSG00000239732 ENSG00000115415 ENSG00000168610 PMC8117215__F2 Early Emergence of Adaptive Mechanisms Sustaining Ig Production: Application to Antibody Therapy ENSG00000128272 ENSG00000100219 ENSG00000012174 PMC5935119__F2 Genetics of coronary artery disease: discovery, biology and clinical translation ENSG00000167772 ENSG00000132855 PMC5334259__F2 Cellular unfolded protein response mechanisms ENSG00000100219 PMC7149109__F1 Antiviral innate immune response ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000243646 ENSG00000131323 ENSG00000175104 ENSG00000249624 PMC7736127__F1 Neuronal insulin signaling and brain structure in non-demented older adults: The ARIC Study ENSG00000169047 PMC5074855__F7 Lactic acid bacteria differentially regulate filamentation in two heritable cell types of the human fungal pathogen Candida albicans ENSG00000196511 PMC7682536__F1 Spectrum of RAS-MAPK pathway disease genes and associated RASopathies ENSG00000157764 ENSG00000110395 ENSG00000143622 ENSG00000166068 ENSG00000126458 ENSG00000108061 ENSG00000062485 PMC3492703__F1 Biosynthesis and posttranscriptional processing of miRNA ENSG00000100697 ENSG00000128191 ENSG00000113360 PMC3943767__F3 Proteolytic pathway that controls glucose uptake in fat and muscle ENSG00000169047 ENSG00000136111 ENSG00000122042 PMC3775123__F2 Signaling modules that are important therapeutic targets to counteract muscle wasting ENSG00000198793 ENSG00000118515 ENSG00000140443 PMC3632064__F3 Motor axons release Agrin and ACh ENSG00000134569 ENSG00000030304 ENSG00000099942 PMC3775123__F1 Signaling modules responsible for autophagy-lysosome pathway in the adult ENSG00000090432 ENSG00000152348 ENSG00000144848 ENSG00000158828 ENSG00000112561 ENSG00000145782 ENSG00000057663 PMC7232389__F6 Eukaryotic initiation factor 2 (EIF2) signaling pathway ENSG00000131469 ENSG00000110700 ENSG00000291931 ENSG00000198918 ENSG00000274700 ENSG00000197728 ENSG00000147604 ENSG00000188846 ENSG00000138326 ENSG00000171863 ENSG00000105647 ENSG00000108107 ENSG00000280858 ENSG00000066336 ENSG00000197958 ENSG00000184110 ENSG00000149273 ENSG00000149806 ENSG00000133056 ENSG00000086991 ENSG00000092847 ENSG00000156976 ENSG00000278270 ENSG00000174444 ENSG00000083845 ENSG00000172809 ENSG00000149311 ENSG00000161016 ENSG00000117020 ENSG00000104237 ENSG00000011304 ENSG00000100302 ENSG00000006451 ENSG00000144118 ENSG00000100353 ENSG00000149100 ENSG00000112306 ENSG00000123908 PMC7232389__F7 Sirtuin signaling pathway ENSG00000131473 ENSG00000142192 ENSG00000284774 ENSG00000126775 ENSG00000073578 ENSG00000117118 ENSG00000198793 ENSG00000283100 ENSG00000132170 ENSG00000114767 ENSG00000143252 ENSG00000282228 ENSG00000108179 ENSG00000152556 PMC8259493__F2 Insights into Autosomal Dominant Polycystic Kidney Disease from Genetic Studies ENSG00000008710 ENSG00000198793 PMC6627458__F8 Mechanisms underlying the anti-inflammatory effects of oxytocin (OT) on lipopolysaccharide (LPS)-stimulated microglia ENSG00000128272 ENSG00000125538 ENSG00000136869 PMC5687887__F1 Summary of pathways and signals discussed in this review that induce NK cell activation and/or NKG2D ligand expression in tumor cells and in virus-infected cells ENSG00000149311 ENSG00000175054 ENSG00000164430 ENSG00000128272 ENSG00000171720 PMC8005482__F1 Inactivation of tumor suppressors in GBM cells that affect GAM biology ENSG00000168329 ENSG00000108691 ENSG00000291971 ENSG00000198793 ENSG00000168036 ENSG00000121807 ENSG00000168610 ENSG00000196712 PMC9678997__S1 Tyrosine hydroxylase–dopamine pathway in Parkinson’s disease pathogenesis ENSG00000158828 PMC4747365__F7 Molecular mechanisms of cisplatin cytotoxicity in acute promyelocytic leukemia cells ENSG00000132906 ENSG00000164305 PMC3743775__F6 Cis Association of Galectin-9 with Tim-3 Differentially Regulates IL-12/IL-23 Expressions in Monocytes via TLR Signaling ENSG00000115415 ENSG00000168610 PMC9237930__F1 New dawn for cancer cell death: Emerging role of lipid metabolism ENSG00000108839 ENSG00000087253 ENSG00000135218 ENSG00000130164 ENSG00000284099 ENSG00000113161 ENSG00000169710 ENSG00000067900 ENSG00000075239 ENSG00000146648 PMC9237930__F2 New dawn for cancer cell death: Emerging role of lipid metabolism ENSG00000065833 ENSG00000135218 ENSG00000092470 ENSG00000134824 ENSG00000186480 ENSG00000169710 ENSG00000077463 ENSG00000096717 ENSG00000198911 PMC7335402__F3 Relevant biological network containing the DPTs and their associated genes () was constructed using Cytoscape version 3.8.0 ENSG00000152348 ENSG00000123395 ENSG00000145782 ENSG00000057663 PMC5516940__F3A Proteomics analyses of prostate cancer cells reveals cellular pathways associated with androgen resistance ENSG00000177455 ENSG00000124102 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000136997 PMC5043055__F5 Pathways leading to lignin and heteroxylan in maize pericarp at stage R3 ENSG00000165757 ENSG00000084774 PMC9170863__F4 TEMTing target? Clinical and experimental evidence for epithelial-mesenchymal transition in the progression of cutaneous squamous cell carcinoma (a scoping systematic review) ENSG00000167601 ENSG00000292222 ENSG00000069482 ENSG00000198793 ENSG00000168036 ENSG00000168610 ENSG00000146648 ENSG00000136826 PMC6881378__F11 Proposed mechanisms for the role of MC mediators in response to tumor cells ENSG00000069482 ENSG00000132646 PMC6368395__F3 Immunosuppressive agent-induced cell-intrinsic tumorigenic pathways ENSG00000019991 ENSG00000186810 ENSG00000162772 ENSG00000168610 PMC6858953__F1 Claudins inhibit multiple oncogenic pathways ENSG00000005882 ENSG00000131023 ENSG00000140443 PMC6368395__F4 Oncogenic viral infections in post-transplantation malignancies ENSG00000168040 ENSG00000146648 ENSG00000026103 PMC8413833__F8 Exosome-mediated transfer of MIF confers temozolomide resistance by regulating TIMP3/PI3K/AKT axis in gliomas ENSG00000100234 ENSG00000123374 PMC3887921__F2 Regulation of autophagy by nutrient signals ENSG00000177169 ENSG00000110497 ENSG00000123395 ENSG00000198382 ENSG00000198793 PMC4905265__F1 Schematic description of multiciliogenesis ENSG00000171444 PMC9364625__F5 Metabolic profiles of regulatory T cells and their adaptations to the tumor microenvironment: implications for antitumor immunity ENSG00000135218 ENSG00000198793 ENSG00000169710 ENSG00000049768 ENSG00000106546 PMC9364625__F3 Metabolic profiles of regulatory T cells and their adaptations to the tumor microenvironment: implications for antitumor immunity ENSG00000179934 ENSG00000126353 PMC9364625__F4 Metabolic profiles of regulatory T cells and their adaptations to the tumor microenvironment: implications for antitumor immunity ENSG00000049768 PMC4314111__F2 Rise of regulatory RNA ENSG00000092847 ENSG00000113360 ENSG00000102974 PMC7143458__F3 Location of differentially expressed genes (indicated by red boxes) in the purine metabolic pathway ENSG00000254550 PMC6889944__F7 Proposed antifibrotic mechanism of G PMC10530916__F8 Endoplasmic Reticulum Stress-Related Ten-Biomarker Risk Classifier for Survival Evaluation in Epithelial Ovarian Cancer and TRPM2: A Potential Therapeutic Target of Ovarian Cancer ENSG00000115415 ENSG00000109320 ENSG00000173039 ENSG00000185591 ENSG00000168610 ENSG00000132170 PMC8687677__F1 The Role of Gut Microbiota in Diabetic Retinopathy ENSG00000162711 ENSG00000172936 ENSG00000136869 PMC9364625__F2 Metabolic profiles of regulatory T cells and their adaptations to the tumor microenvironment: implications for antitumor immunity ENSG00000135218 ENSG00000198793 PMC6341905__F1 TGF and RBM5 signaling cascade ENSG00000002330 ENSG00000003756 ENSG00000163235 ENSG00000138798 PMC8199164__F4 Current Implications of microRNAs in Genome Stability and Stress Responses of Ovarian Cancer ENSG00000188486 ENSG00000012048 ENSG00000175054 ENSG00000111602 ENSG00000163961 ENSG00000051180 ENSG00000142731 ENSG00000112130 PMC4449425__F2 Activation of canonical (Wnt–Beta-catenin) pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6934488__F6 Metabolic network diagram between phenylpropanoid biosynthesis pathway, pentose phosphate pathway and proline metabolic pathway ENSG00000100033 ENSG00000084774 PMC9043410__F4 Structure-based identification and pathway elucidation of flavonoids in Camptotheca acuminate PMC7567033__F1 Scheme of the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway in the regulation of autophagy process ENSG00000177169 ENSG00000110497 ENSG00000123395 ENSG00000198382 ENSG00000126775 ENSG00000155792 ENSG00000146648 ENSG00000187840 ENSG00000196712 PMC11414392__F11 RUNX1-MUC13 regulatory mechanisms in CRC metastasis ENSG00000159216 ENSG00000168646 ENSG00000173702 PMC9226665__F6 Endotoxins Induced ECM-Receptor Interaction Pathway Signal Effect on the Function of MUC2 in Caco2/HT29 Co-Culture Cells ENSG00000041982 ENSG00000142798 ENSG00000029559 ENSG00000291971 ENSG00000188157 ENSG00000026508 ENSG00000172037 PMC8615041__F1 IL-36A and Lipopolysaccharide Cooperatively Induce Autophagy by Triggering Pro-Autophagic Biased Signaling ENSG00000198793 ENSG00000136694 ENSG00000150455 ENSG00000168610 ENSG00000057663 ENSG00000170458 ENSG00000177606 ENSG00000144848 ENSG00000134070 ENSG00000136869 ENSG00000172936 ENSG00000145782 ENSG00000184216 PMC7272533__F1 IL-18 signaling pathway ENSG00000002330 ENSG00000173039 ENSG00000162924 ENSG00000213341 ENSG00000255690 ENSG00000168040 ENSG00000162772 ENSG00000175054 ENSG00000196531 ENSG00000150782 ENSG00000177606 ENSG00000124795 ENSG00000159335 ENSG00000122971 ENSG00000127948 ENSG00000026103 ENSG00000291368 PMC8070103__F1 RAF-MEK-ERK pathway is activated by H/K and NRAS upon extracellular stimuli ENSG00000157764 PMC2711664__F1 Signal transduction mechanisms implicated in leptin action ENSG00000198793 ENSG00000168610 PMC8070103__F4 RAF1 negatively regulates the proapoptotic Hippo pathway by binding to MST2 upon growth factor stimulation ENSG00000131023 ENSG00000026103 PMC10982327__F2 Molecular pathways involved in animal glaucoma models at the level of retinal ganglion cell ENSG00000291971 ENSG00000026103 PMC8163539__F4 Systematic Pharmacology Reveals the Antioxidative Stress and Anti-Inflammatory Mechanisms of Resveratrol Intervention in Myocardial Ischemia-Reperfusion Injury ENSG00000172936 ENSG00000150455 ENSG00000135517 PMC2869556__F1 Metabolic folate pathway ENSG00000228716 ENSG00000124275 ENSG00000116984 PMC2898136__F6 Eicosanoids and cancer ENSG00000108691 ENSG00000070831 ENSG00000146648 ENSG00000121966 PMC2898136__F3 Eicosanoids and cancer ENSG00000087245 ENSG00000291971 ENSG00000126353 ENSG00000146648 PMC2898136__F1 Eicosanoids and cancer ENSG00000226275 PMC5940378__F7 Proposed aPPD anti-prostate cancer mechanism PMC4649380__F5 CTGF Signaling Network ModelWe compiled a list of molecules known to be associated with hematopoiesis () and reported to interact directly or indirectly with CTGF and each other using EXERBT text mining and Pathway Commons, respectively ( and ) ENSG00000259207 ENSG00000197081 ENSG00000105329 ENSG00000162337 ENSG00000174804 ENSG00000168036 ENSG00000124762 ENSG00000157240 ENSG00000145604 ENSG00000163251 ENSG00000135446 ENSG00000136997 ENSG00000150907 ENSG00000104290 ENSG00000123374 ENSG00000105810 ENSG00000177283 ENSG00000155760 ENSG00000146648 ENSG00000175305 PMC7962393__F7 Functional Prediction of the Key Genes Involved in HBV Associated HCC ENSG00000137804 ENSG00000118007 ENSG00000105329 ENSG00000102871 ENSG00000087586 ENSG00000112118 ENSG00000073111 ENSG00000145386 ENSG00000134480 ENSG00000072571 ENSG00000137807 ENSG00000138778 ENSG00000148773 ENSG00000113558 ENSG00000136997 ENSG00000115942 ENSG00000123374 ENSG00000105810 ENSG00000139687 ENSG00000253729 ENSG00000108055 ENSG00000175793 ENSG00000131747 ENSG00000138160 ENSG00000149311 ENSG00000117724 ENSG00000145604 ENSG00000198901 ENSG00000111665 ENSG00000117650 ENSG00000122952 ENSG00000134057 ENSG00000024526 ENSG00000101003 ENSG00000112984 ENSG00000132646 ENSG00000164754 PMC4928090__F4 Transcriptome comparison reveals a genetic network regulating the lower temperature limit in fish ENSG00000109819 ENSG00000110395 ENSG00000138764 ENSG00000100994 ENSG00000240445 ENSG00000111713 ENSG00000154415 ENSG00000118515 ENSG00000132356 ENSG00000168610 ENSG00000124762 ENSG00000168685 PMC2518078__F1 Cotargeting survival signaling pathways in cancer ENSG00000002330 PMC7439842__F1 Known and speculated roles of NADPH oxidase (Nox) and ROS in G-protein-coupled receptor (GPCR) transactivation of epidermal growth factor receptor (EGFR) ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC7312018__F4 Tamoxifen modulation of membrane and nuclear estrogen receptor (ER) signaling ENSG00000105329 ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC6319021__F5 Proposed mechanism for kCer acting as a Sema3A-like ligand ENSG00000106683 ENSG00000010810 ENSG00000075213 PMC20092__F5 A model for the v-Crk-mediated signaling pathway ENSG00000177606 PMC5852877__F1 TLR4 intracellular signaling pathways ENSG00000183735 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC12023698__F7 Working model of AMPK-ULK1 activating autophagy in nZnO induced bone regeneration ENSG00000178860 ENSG00000177169 ENSG00000291837 PMC9520460__F10 Complement C1q/C3-CR3 signaling in brain injury after experimental intracerebral hemorrhage and the effect of minocycline treatment ENSG00000177575 PMC10891054__F9 PART1/AC007728 ENSG00000281123 PMC7757025__F3 Signal transduction of BII spectrin in tumor ENSG00000281324 ENSG00000162337 ENSG00000144554 ENSG00000119888 ENSG00000134982 ENSG00000135446 ENSG00000168036 ENSG00000136869 ENSG00000114315 ENSG00000168610 ENSG00000136231 PMC9224204__F4 Chronic LY341495 on Hippocampal mTORC1 Signaling in Mice with Chronic Unpredictable Stress-Induced Depression PMC8598308__F5 Genome-Wide Correlation of DNA Methylation and Gene Expression in Postmortem Brain Tissues of Opioid Use Disorder Patients ENSG00000275723 ENSG00000163686 ENSG00000117480 ENSG00000134780 PMC5116860__F3 Mechanism of action of metformin ENSG00000008710 ENSG00000198793 PMC6513775__F4 Possible site of action of beta (B) asarone in apoptosis, cell proliferation and growth ENSG00000123374 PMC8450533__F4 RhoA/ROCK-YAP/TAZ Axis Regulates the Fibrotic Activity in Dexamethasone-Treated Human Trabecular Meshwork Cells ENSG00000100290 ENSG00000113456 ENSG00000002330 ENSG00000213658 ENSG00000070831 ENSG00000163914 ENSG00000198125 ENSG00000119912 ENSG00000160293 ENSG00000196712 ENSG00000084774 PMC8450533__F5 RhoA/ROCK-YAP/TAZ Axis Regulates the Fibrotic Activity in Dexamethasone-Treated Human Trabecular Meshwork Cells ENSG00000137834 ENSG00000169291 ENSG00000111537 ENSG00000002330 ENSG00000095739 ENSG00000187720 ENSG00000198742 ENSG00000113558 ENSG00000174136 ENSG00000156574 ENSG00000205250 PMC4889429__F2 MiR-155 on virulent (green) and avirulent (yellow) Mycobacterium species infection in macrophage ENSG00000171033 PMC8326283__F8 Liquid–liquid phase separation in human health and diseases ENSG00000121067 PMC12230579__F7 Network of compound-reaction-enzyme-gene ENSG00000101670 ENSG00000184254 ENSG00000110721 ENSG00000073578 ENSG00000100288 ENSG00000095321 ENSG00000107798 ENSG00000105953 ENSG00000023909 ENSG00000129219 ENSG00000178814 ENSG00000072210 ENSG00000161618 ENSG00000291895 ENSG00000196620 ENSG00000079435 ENSG00000166123 ENSG00000091140 ENSG00000115419 ENSG00000133027 ENSG00000062485 ENSG00000167701 PMC8326283__F6 Liquid–liquid phase separation in human health and diseases ENSG00000291603 ENSG00000164430 ENSG00000213658 ENSG00000115904 PMC7696687__F3 Various physiological roles of intracellular visfatin (iNAMPT) ENSG00000187531 ENSG00000123572 ENSG00000157064 ENSG00000077463 ENSG00000173614 ENSG00000008130 ENSG00000096717 ENSG00000142082 ENSG00000283100 PMC5518130__F4 Differently expressed protein-coding genes and lncRNAs participating in the AMPK signaling pathway via DAVID KEGG analysis ENSG00000180210 ENSG00000171105 ENSG00000135218 ENSG00000198793 ENSG00000284161 ENSG00000001626 ENSG00000164087 ENSG00000026103 PMC3875959__F3 Proposed model for the role of lncRNAs in RB pathway ENSG00000105810 PMC4470747__F1 Innate Immune Evasion In Re-Emerging RNA Viruses ENSG00000183735 ENSG00000088888 ENSG00000175104 ENSG00000121060 ENSG00000276561 ENSG00000123908 ENSG00000164342 PMC7269781__F3 BRCA pathway ENSG00000149311 ENSG00000175054 ENSG00000123268 ENSG00000156273 PMC10384352__F2 Review: Understanding Molecular Mechanisms of Antibody-Dependent Enhancement in Viral Infections ENSG00000288512 ENSG00000182326 ENSG00000236625 PMC10384352__F3 Review: Understanding Molecular Mechanisms of Antibody-Dependent Enhancement in Viral Infections ENSG00000104972 ENSG00000057663 PMC5989766__F8 Impaired Akt signalling leads to iron accumulation ENSG00000142192 PMC4191269__F1 Controller composed of the KDEL receptor (KDELR) and the Gq and Gs signaling pathways maintains the homeostasis of membrane transport at the Golgi complex ENSG00000291971 ENSG00000185591 ENSG00000162772 ENSG00000123268 PMC7052944__F5 Regulatory effect of GPC3 on the WNT signaling pathway ENSG00000168036 PMC5021733__F1 Negative regulators of Toll-like receptor signaling ENSG00000174125 ENSG00000226275 ENSG00000239732 ENSG00000187554 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC5823541__F1 MTOR signaling pathway and the cell cycle pathway associated with lung adenocarcinoma as reported in ENSG00000149311 ENSG00000198793 ENSG00000196712 PMC9218900__F3 Intersection of Acute Kidney Injury and Non-Coding RNAs: Inflammation ENSG00000278718 ENSG00000162711 ENSG00000144802 ENSG00000189403 ENSG00000162924 ENSG00000175104 ENSG00000168610 ENSG00000184216 PMC4370254__F1 Schematic depiction of sonic hedgehog (SHH) synthesis, secretion, and signaling ENSG00000180447 ENSG00000106571 ENSG00000164161 ENSG00000144857 ENSG00000154309 ENSG00000164690 ENSG00000128602 PMC7696687__F1 Three-mammalian nicotinamide adenine dinucleotide (NAD+) biosynthesis pathways ENSG00000157064 ENSG00000173614 PMC5354895__F14 Cancer upregulated gene 2 induces epithelial-mesenchymal transition of human lung cancer cells via TGFB signaling ENSG00000170558 ENSG00000185591 PMC8399569__F5 Plant Salicylic Acid Signalling Pathway Regulates the Infection of a Biotrophic Pathogen in Grasses Associated with an Epichloë Endophyte ENSG00000121058 ENSG00000136997 PMC11192764__F1 TGFB complex and TGFBR signaling pathways PMC7696687__F2 Salvage (rescue) pathway remains a predominant pathway to meet NAD+ cellular requirements ENSG00000105835 PMC7727191__F3 Signaling pathways which CD44 regulates ENSG00000087245 ENSG00000291971 ENSG00000026508 ENSG00000168036 ENSG00000100985 PMC5844972__F2 Three pathways of the unfolded protein response (UPR) ENSG00000128272 ENSG00000100219 ENSG00000115419 PMC6148250__F8 S100A10 and PAI-1 are regulated by Smad4-dependent TGFB1-mediated signaling and FOXC2-mediated PI3K signaling ENSG00000197747 ENSG00000176692 ENSG00000105329 ENSG00000198793 PMC3723114__F1 Canonical and noncanonical TGFB signaling systems activated during mammary tumorigenesis PMC7349823__F7 Distinct mechanism of miR-210 in the regulation of mouse and cattle adipogenesis ENSG00000168036 ENSG00000196628 ENSG00000102935 PMC6558396__F1 Drosophila Hippo pathway Network ENSG00000132471 ENSG00000132849 ENSG00000072415 PMC8590693__F7 Hypothetical model illustrating multiple actions of NCT-58 on cancer stem-like properties, HER2 signaling, and trastuzumab resistance in HER2-positive breast cancer ENSG00000284774 ENSG00000026508 PMC8431385__F2 Investigating the Molecular Processes behind the Cell-Specific Toxicity Response to Titanium Dioxide Nanobelts ENSG00000002330 ENSG00000105327 ENSG00000282905 ENSG00000153094 ENSG00000120889 ENSG00000180644 ENSG00000171791 ENSG00000089685 ENSG00000136997 ENSG00000137265 ENSG00000168310 ENSG00000120868 ENSG00000135116 ENSG00000140443 ENSG00000026103 ENSG00000132906 ENSG00000104365 ENSG00000196954 ENSG00000269335 ENSG00000065559 ENSG00000162924 ENSG00000213341 ENSG00000215788 ENSG00000226275 ENSG00000258643 PMC8431385__F3 Investigating the Molecular Processes behind the Cell-Specific Toxicity Response to Titanium Dioxide Nanobelts ENSG00000116044 ENSG00000109320 ENSG00000086991 ENSG00000008394 ENSG00000163918 ENSG00000115350 ENSG00000077514 ENSG00000035928 ENSG00000140465 ENSG00000158125 ENSG00000211445 ENSG00000148229 ENSG00000113318 ENSG00000132646 ENSG00000132383 ENSG00000100479 ENSG00000100348 ENSG00000277897 ENSG00000074771 ENSG00000106628 ENSG00000177084 ENSG00000133119 ENSG00000095002 ENSG00000122512 PMC4542789__F3 Sub-network of genes regulated by E2F3, E2F4, and the E2F functional group ENSG00000033327 ENSG00000117298 ENSG00000112118 ENSG00000145386 ENSG00000076003 ENSG00000118971 ENSG00000166508 ENSG00000242265 ENSG00000078900 ENSG00000115942 ENSG00000051180 ENSG00000112029 ENSG00000183779 ENSG00000112742 ENSG00000114346 ENSG00000164109 ENSG00000179091 ENSG00000138794 ENSG00000086991 ENSG00000167900 ENSG00000145604 ENSG00000065328 ENSG00000156802 ENSG00000134057 ENSG00000132646 ENSG00000095002 ENSG00000080839 ENSG00000175305 PMC3429121__F2 Metabolic flux through the purine salvage pathway in L ENSG00000137198 ENSG00000198931 ENSG00000119125 PMC6592070__F1 CAMP/PKA pathway in S ENSG00000069482 ENSG00000116741 ENSG00000169299 PMC6592070__F2 CAMP/PKA pathway in C ENSG00000159224 ENSG00000069482 ENSG00000169299 PMC10572524__F7 DEGs in NOD/Toll-like receptor signaling pathway ENSG00000213928 ENSG00000081041 ENSG00000187796 ENSG00000187554 ENSG00000136869 ENSG00000276068 PMC11820663__F4 Macrophage polarization-related signaling pathway (by Figdraw) ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC11592674__F6 Simulated microgravity effects on transcriptomic profile of bone marrow cell culture ENSG00000129474 ENSG00000166341 ENSG00000126016 ENSG00000291971 ENSG00000162551 ENSG00000134308 ENSG00000139926 ENSG00000150457 ENSG00000132849 ENSG00000144791 ENSG00000131023 ENSG00000164305 ENSG00000072415 ENSG00000074219 ENSG00000186575 ENSG00000142279 ENSG00000143995 PMC7709628__F1 Interplay between nutrient-sensing pathways potentially affecting health span ENSG00000105550 ENSG00000198793 PMC7709628__F2 Specific nutrients and dietary manipulations affecting insulin/insulin-like growth factor signaling (IIS) pathway ENSG00000171105 ENSG00000105550 ENSG00000198793 PMC11770381__F5 Neutrophils in CAC ENSG00000163739 ENSG00000167468 ENSG00000100985 ENSG00000047936 ENSG00000204936 ENSG00000168610 PMC6173473__F3 Crosstalk of bone cells within bone marrow regulates bone remodeling, adipogenesis, hematopoiesis, and angiogenesis ENSG00000178860 ENSG00000081041 ENSG00000132170 PMC6592070__F3 Connections between the cAMP/PKA pathway and virulence-related functions in C ENSG00000138433 ENSG00000047936 PMC5250648__F2 Ca2+ induces autophagy ENSG00000198793 ENSG00000112561 ENSG00000055732 PMC2861491__F1 Destruction of the Beta-catenin (Beta-Cat) destructor Axin ENSG00000134982 ENSG00000107854 ENSG00000168036 PMC5357773__F5 FcGRIIIb initiates signaling pathways to the nucleus ENSG00000291971 PMC8805398__F1 Rapamycin, Acarbose and 17Alpha-estradiol share common mechanisms regulating the MAPK pathways involved in intracellular signaling and inflammation PMC6813288__F3 Mechanism of NFKB activation by PA ENSG00000144895 ENSG00000136869 ENSG00000175104 PMC6548160__F3 CSC signaling pathways which are regulated by BRCA proteins ENSG00000012048 ENSG00000148400 ENSG00000164690 ENSG00000139549 ENSG00000163501 PMC2575845__F1 RLR signaling pathway and its negative regulatory molecules ENSG00000183735 ENSG00000187608 ENSG00000160703 ENSG00000131323 ENSG00000083799 ENSG00000168040 ENSG00000175104 ENSG00000121060 ENSG00000101695 PMC2782488__F1 Cytokine signaling modules in inflammatory responses ENSG00000162594 ENSG00000103522 ENSG00000049768 ENSG00000168610 ENSG00000168685 ENSG00000069667 PMC2782488__F3 Cytokine signaling modules in inflammatory responses ENSG00000108691 ENSG00000163739 ENSG00000168610 PMC6122031__F9 Putative regulatory mechanisms of the FNM process ENSG00000134982 PMC2864712__F10 PAK4 regulates adhesion and migration via multiple signalling pathways ENSG00000019991 ENSG00000130669 PMC8931538__F9 JAM-A–tetraspanin–AvB5 integrin complex regulates contact inhibition of locomotion ENSG00000291971 ENSG00000110651 ENSG00000010278 ENSG00000213523 PMC8429033__F7 Blocking the Hepatic Branch of the Vagus Aggravates Hepatic Ischemia-Reperfusion Injury via Inhibiting the Expression of IL-22 in the Liver ENSG00000105397 ENSG00000168610 PMC3868890__F2 Main synaptic signaling mechanisms of endocannabinoid and hypocretinergic systems ENSG00000148798 ENSG00000121764 PMC1322299__F1 Tweaking Microtubules to Treat Scleroderma PMC5492089__F7 Schematic of canonical Hh pathway ENSG00000106571 ENSG00000128602 PMC4110715__F5 GeneGo graphic representation illustrates Transcription Androgen Receptor (AR) nuclear signaling ENSG00000087245 ENSG00000084676 ENSG00000138798 ENSG00000155974 ENSG00000168610 ENSG00000146648 PMC3872778__F2 Similarities between NAA synthesis and citrate synthesis ENSG00000172005 ENSG00000062485 PMC3590129__F7 Differential Expression of miR-145 in Children with Kawasaki Disease PMC5975367__F3 Targeting Autophagy in Cancer ENSG00000149311 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000168610 ENSG00000146648 PMC4222471__F2 RAS signaling pathway and genes mutated in juvenile myelomonocytic leukemia (in black) ENSG00000110395 ENSG00000198793 ENSG00000115904 ENSG00000196712 PMC4197205__F1 An IL-1-induced signaling pathway is mediated by K63-linked polyubiquitination of IRF1 ENSG00000175104 PMC7349538__F9 Biological model proposed for the yeast response to stress caused by inorganic acids ENSG00000180447 ENSG00000101871 PMC2213034__F8 Our model for the mechanism of anti-CD63 inhibition ENSG00000033327 ENSG00000010810 ENSG00000135404 PMC9331907__F3 Metabolism on Macrophage Polarization Under Different Disease Backgrounds ENSG00000125538 ENSG00000026103 PMC7488362__F2 Diagram depicting the mechanism of CR involving multiple signaling pathways ENSG00000033327 ENSG00000148400 ENSG00000291971 ENSG00000134982 ENSG00000113070 ENSG00000198793 ENSG00000163914 ENSG00000026508 ENSG00000168036 ENSG00000067900 ENSG00000146648 PMC5105878__F1 Schematic overview of the stepwise mechanisms involved in the development of immunoglobulin E (IgE)-mediated food allergy ENSG00000137033 ENSG00000145777 ENSG00000166090 PMC8501036__F7 Proposed mechanistic pathway for the Fe2O3@KO2/zeolite catalyzed hydrogenation of CO2, highlighting the efficacy of our multifunctional system ENSG00000100473 ENSG00000154059 PMC10648679__F1 PSCs have emerged as a promising candidate for stem cells in PDAC ENSG00000168036 PMC7760557__F9 Melatonin in mitochondria of WT mice during cardiac aging ENSG00000162711 ENSG00000116688 ENSG00000148798 ENSG00000168040 ENSG00000145020 ENSG00000079999 PMC6570498__F1 Endogenous H2S production, metabolism during methionine cycle PMC5946314__F1 Manipulating the PD-1 pathway to improve immunity ENSG00000291603 ENSG00000134982 PMC8752351__F3 CD36 in cardiovascular disease ENSG00000171105 ENSG00000135218 ENSG00000150907 PMC2853371__F9 CD28 costimulation, IL-2 signaling, and mTOR pathway regulate Otub1 and GRAIL expression, controlling proliferation in primary naive CD4 T cells ENSG00000134982 ENSG00000198793 ENSG00000173599 PMC9616467__F8 Embryonic transcriptome unravels mechanisms and pathways underlying embryonic development with respect to muscle growth, egg production, and plumage formation in native and broiler chickens ENSG00000112576 ENSG00000169071 ENSG00000143878 ENSG00000030304 ENSG00000198793 ENSG00000172572 ENSG00000169710 ENSG00000076555 ENSG00000135341 ENSG00000100485 ENSG00000187840 ENSG00000115290 ENSG00000182533 ENSG00000106617 ENSG00000074800 ENSG00000115457 ENSG00000139725 ENSG00000150907 ENSG00000146678 ENSG00000147082 ENSG00000136872 ENSG00000146648 ENSG00000113448 ENSG00000172399 PMC6668486__F2 NK cell transduction pathways involved in primary immunodeficiencies ENSG00000104856 ENSG00000111537 ENSG00000115415 ENSG00000164136 ENSG00000185745 ENSG00000173039 PMC3248020__F9 Schematic representation of S100A7-mediated signaling that inhibits proliferation and motility in ERA+ breast cancer ENSG00000168036 ENSG00000143556 PMC7073073__F8 Representation of ATF6 acting on the TGFB–Smad pathway for induction of fibrosis genes ENSG00000198742 ENSG00000108821 PMC8100607__F3 Reporters of Cancer Stem Cells as a Tool for Drug Discovery ENSG00000129654 ENSG00000168036 PMC8100607__F1 Reporters of Cancer Stem Cells as a Tool for Drug Discovery ENSG00000118777 PMC9378776__F2 Tryptophan in Chlamydia trachomatis persistence ENSG00000140505 ENSG00000118520 ENSG00000140465 ENSG00000106546 PMC9414242__F1 Recent Advances in Nanoparticles-Based Platforms Targeting the PD-1/PD-L1 Pathway for Cancer Treatment ENSG00000134982 ENSG00000214285 PMC5015042__F1 The mTORC1 amino acid–sensing pathway ENSG00000177058 ENSG00000143761 ENSG00000239282 PMC7019991__F2 Representative image describing the role of the NOTCH/JAG1 pathway in AML-MSCs of a model describing MSCs in human BM niche ENSG00000049130 ENSG00000174059 ENSG00000114315 PMC11874752__F8 Schematic diagram displays the function of FLJ in CRPC ENSG00000177169 ENSG00000083290 PMC11635105__F4 STRING protein-protein interaction networks for the differentially methylated circadian pathways-related genes in HS ENSG00000152684 ENSG00000038002 ENSG00000176102 PMC6563219__F3 Pathway visualization using downregulated differentially-expressed unigenes in Axon guidance, Regulation of actin cytoskeleton and Adherens junction ENSG00000070831 ENSG00000291971 ENSG00000134982 ENSG00000010810 ENSG00000168036 ENSG00000185008 PMC6563219__F4 Pathway visualization using downregulated differentially-expressed unigenes in cAMP signaling, Focal adhesion, Calcium signaling, Hippo signaling in fly and Notch signaling ENSG00000106571 ENSG00000163914 ENSG00000168036 PMC4111923__F2 An example of a CN: the EGF signaling pathway includes > 60 proteins and has several alternative pathways (from http://www.sabiosciences.com/pathwaycentral.php, where many other networks are also shown) ENSG00000115415 ENSG00000149269 ENSG00000138798 ENSG00000163914 ENSG00000144566 ENSG00000168610 ENSG00000146648 PMC7723514__F6 Pimozide in prolactinoma bromocriptine resistance ENSG00000113494 PMC4060531__F3 Genetic Basis of Diffuse Large B Cell Lymphoma ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000137265 ENSG00000172936 ENSG00000198286 PMC7311368__F1 Obesity and Breast Cancer: The Role of Crown-Like Structures in Breast Adipose Tissue in Tumor Progression, Prognosis, and Therapy ENSG00000108691 ENSG00000137033 ENSG00000125538 PMC6815593__F9 Schematic mechanism of matrine signaling pathway that inhibits cell growth and leads to cell death in HL-7702 cells ENSG00000132906 ENSG00000123374 ENSG00000064012 ENSG00000164305 ENSG00000079999 ENSG00000026103 PMC5336494__F2 Diagram of signaling pathways that control Notch expression in PC ENSG00000008710 ENSG00000146648 ENSG00000198363 PMC8076903__F1 TRP Channels in Brain Tumors ENSG00000019991 ENSG00000092439 ENSG00000104321 ENSG00000133937 ENSG00000138798 ENSG00000156026 ENSG00000131095 ENSG00000162772 ENSG00000168610 ENSG00000100422 ENSG00000187688 ENSG00000144935 ENSG00000163914 ENSG00000137672 ENSG00000196689 ENSG00000026103 PMC4086465__F1 NKT-cell subsets: Promoters and protectors in inflammatory liver disease ENSG00000134982 ENSG00000026103 PMC5336494__F1 Diagram of Notch signaling ENSG00000100985 PMC6142530__F1 Novel agents and pathways under investigation in MDS ENSG00000198793 PMC2856528__F1 The three complement activation pathways, converging to cleave C3 ENSG00000288512 ENSG00000166278 ENSG00000182326 ENSG00000236625 PMC2963059__F2 Non-canonical Wnt pathways ENSG00000087095 ENSG00000070831 ENSG00000100592 ENSG00000168036 PMC1998879__F2 Molecular pathway associated with neuronal migration ENSG00000166579 ENSG00000077279 ENSG00000173406 PMC2963059__F1 Canonical Wnt/Beta-catenin pathway ENSG00000134982 ENSG00000168036 PMC7601404__F1 Arginine biosynthesis ENSG00000124357 PMC9433876__F1 Hippo-YAP pathway in various cardiovascular diseases: Focusing on the inflammatory response ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC9433876__F2 Hippo-YAP pathway in various cardiovascular diseases: Focusing on the inflammatory response ENSG00000177575 ENSG00000107562 ENSG00000111537 ENSG00000118785 ENSG00000163739 ENSG00000184371 ENSG00000136869 ENSG00000118520 PMC9433876__F3 Hippo-YAP pathway in various cardiovascular diseases: Focusing on the inflammatory response ENSG00000150457 ENSG00000131023 PMC9433876__F4 Hippo-YAP pathway in various cardiovascular diseases: Focusing on the inflammatory response ENSG00000100106 ENSG00000175104 ENSG00000131023 ENSG00000156273 PMC2704571__F2 Diagrammatic representation of hormone therapy-induced changes in gene expression in the dorsal raphe block ENSG00000275618 ENSG00000102871 ENSG00000138798 ENSG00000065559 ENSG00000168040 ENSG00000137764 ENSG00000185104 ENSG00000066468 ENSG00000150991 ENSG00000146072 ENSG00000120868 ENSG00000026103 ENSG00000123610 PMC9116906__F2 Neuroprotective Effects of Celastrol in Neurodegenerative Diseases-Unscramble Its Major Mechanisms of Action and Targets ENSG00000105401 ENSG00000127191 ENSG00000168610 PMC9423640__F2 Key genes pathway identification and potential drug design ENSG00000125820 ENSG00000106331 PMC8818874__F5 Confirmation of inhibitingTLR4/MyD88/NFKB Signalling Pathway by Duhuo Jisheng Decoction on Osteoarthritis: A Network Pharmacology Approach-Integrated Experimental Study ENSG00000002330 ENSG00000288174 ENSG00000148344 ENSG00000145386 ENSG00000178726 ENSG00000124762 ENSG00000104368 ENSG00000183765 ENSG00000117525 ENSG00000130164 ENSG00000089685 ENSG00000128052 ENSG00000136997 ENSG00000166501 ENSG00000123374 ENSG00000108821 ENSG00000275565 ENSG00000064012 ENSG00000087245 ENSG00000081041 ENSG00000007908 ENSG00000213341 ENSG00000257335 ENSG00000140465 ENSG00000168610 ENSG00000132170 ENSG00000108839 ENSG00000169245 ENSG00000108691 ENSG00000134057 ENSG00000135446 ENSG00000132646 ENSG00000291748 ENSG00000005381 ENSG00000159399 PMC6107850__F1 Overview of RNA-sensing pathway ENSG00000162711 ENSG00000183735 ENSG00000088888 ENSG00000109606 ENSG00000174953 ENSG00000276561 ENSG00000164342 PMC8314463__F1 Protein farnesylation is upregulated in Alzheimer’s human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer’s model mice ENSG00000163914 ENSG00000197429 ENSG00000113161 PMC8901705__F1 Key therapeutic targets in the pathogenesis of autoimmune diseases ENSG00000162594 ENSG00000177455 ENSG00000105397 ENSG00000134982 ENSG00000163599 ENSG00000125538 ENSG00000145321 ENSG00000103522 ENSG00000105639 PMC8884367__F3 Inhibitory Immune Checkpoint Molecules and Exhaustion of T cells in COVID-19 ENSG00000089692 ENSG00000010810 PMC8409023__F1 Targeting the tumor microenvironment in chronic lymphocytic leukemia ENSG00000177455 ENSG00000186716 ENSG00000113263 ENSG00000010671 PMC2929918__F1 Homocysteine metabolism in the liver PMC6021530__F1 Regulatory functions of oncogenic and tumor suppressor miRNAs on canonical Wnt signaling pathways in HCC ENSG00000087095 ENSG00000168283 ENSG00000134982 ENSG00000020633 ENSG00000026508 ENSG00000168036 PMC6996500__F7 Protein expression profile changes of lung tissue in patients with pulmonary hypertension ENSG00000134755 ENSG00000198626 ENSG00000198947 PMC12189131__F2 Metabolic effects of hydroxybenzoic acid derivatives on the coenzyme Q biosynthesis pathway ENSG00000132423 ENSG00000123815 ENSG00000119723 ENSG00000163050 ENSG00000110871 ENSG00000088682 ENSG00000148459 ENSG00000173085 ENSG00000167186 PMC6996500__F8 Protein expression profile changes of lung tissue in patients with pulmonary hypertension ENSG00000160808 ENSG00000197616 ENSG00000198947 PMC9044593__F8 An EHMT2/NFYA-ALDH2 signaling axis modulates the RAF pathway to regulate paclitaxel resistance in lung cancer ENSG00000001167 PMC3759013__F1 Melanoma: New Insights and New Therapies ENSG00000157404 ENSG00000117020 ENSG00000065833 ENSG00000157764 ENSG00000198793 ENSG00000171791 PMC3556327__F4 Cholesterol biosynthesis theme analysis PMC7026586__F7 TP53BP1 and associated genes are downregulated in prostate cancer ENSG00000012048 ENSG00000163961 ENSG00000080345 ENSG00000067369 ENSG00000112130 PMC2920482__F1 Detection of WNV and activation of IFNA/B genes and ISG according to the 2-step model ENSG00000105397 ENSG00000131323 ENSG00000142166 PMC6209820__F5 Major pathways of cancer immunotherapy of Ganoderma in immune cells ENSG00000117525 ENSG00000170458 ENSG00000120158 PMC9548376__F6 Autism-associated CHD8 keeps proliferation of human neural progenitors in check by lengthening the G1 phase of the cell cycle ENSG00000110395 ENSG00000123374 ENSG00000100888 ENSG00000146648 PMC6920895__F5 The metabolic network and key enzymes in Aurantiochytrium sp ENSG00000102977 ENSG00000026103 PMC3877660__F1 An overview of EGFR and Wnt/Beta-catenin signaling ENSG00000110395 ENSG00000162337 ENSG00000115488 ENSG00000163235 ENSG00000124882 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000137193 ENSG00000168036 ENSG00000146648 ENSG00000165617 PMC5589252__F6 Mapping the STK4/Hippo signaling network in prostate cancer cell ENSG00000110330 ENSG00000105327 ENSG00000105329 ENSG00000073350 ENSG00000044115 ENSG00000134308 ENSG00000168036 ENSG00000132849 ENSG00000170365 ENSG00000186575 ENSG00000078900 ENSG00000163558 ENSG00000136997 ENSG00000134376 ENSG00000113645 ENSG00000126016 ENSG00000138795 ENSG00000107404 ENSG00000109321 ENSG00000150457 ENSG00000081051 ENSG00000072803 ENSG00000140807 ENSG00000068028 ENSG00000115266 ENSG00000019549 ENSG00000142279 PMC8745615__F2 Acute Myeloid Leukemia-Related Proteins Modified by Ubiquitin and Ubiquitin-like Proteins ENSG00000122025 ENSG00000198793 PMC8745615__F3 Acute Myeloid Leukemia-Related Proteins Modified by Ubiquitin and Ubiquitin-like Proteins ENSG00000071575 ENSG00000173334 PMC9687758__F10 Genome-Wide RNA Sequencing of Human Trabecular Meshwork Cells Treated with TGFB1: Relevance to Pseudoexfoliation Glaucoma ENSG00000170365 ENSG00000126016 ENSG00000109321 ENSG00000134982 ENSG00000081051 ENSG00000131023 ENSG00000072415 PMC8156814__F5 Antitumor Activity of Nitazoxanide against Colon Cancers: Molecular Docking and Experimental Studies Based on Wnt/Beta-Catenin Signaling Inhibition ENSG00000132906 ENSG00000002330 ENSG00000134982 ENSG00000163914 ENSG00000164305 PMC6996500__F6 Protein expression profile changes of lung tissue in patients with pulmonary hypertension ENSG00000160808 ENSG00000198947 PMC5346542__F1 Metabolic reprogramming drives: (A) T-cell fate and function and (B) antitumor-immune response ENSG00000163599 ENSG00000198793 ENSG00000136997 PMC11593441__F4 Signaling pathways regulating macrophage (Mφ) polarization ENSG00000148400 ENSG00000115415 ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000118520 ENSG00000131323 ENSG00000150455 ENSG00000121807 ENSG00000175104 ENSG00000168610 PMC10944288__F1 chemokine signaling pathway (hsa04062) as outlined in the KEGG database ENSG00000002330 ENSG00000115718 PMC10778864__F2 VEGF-VEGFR signaling pathway ENSG00000165197 ENSG00000112715 ENSG00000150630 PMC8514798__F2 Germline STAT3 gain-of-function mutations in primary immunodeficiency: Impact on the cellular and clinical phenotype ENSG00000128951 ENSG00000168610 PMC5309818__F3 Reconciled rat and human metabolic networks for comparative toxicogenomics and biomarker predictions ENSG00000183463 PMC11355545__F8 Schematic depicting the signaling pathway ROS/PARP/TRPM2 that causes SiNPs-induced lung inflammation in mice ENSG00000284099 ENSG00000227345 PMC10996061__F2 Impact of amotosalen/UVA treatment on phosphoproteome signaling and platelet pathways ENSG00000162889 ENSG00000291971 ENSG00000197442 PMC11919857__F5 LncRNA-NEAT1 in cancer ENSG00000125398 ENSG00000111837 ENSG00000137573 PMC6966712__F8 Hypothesis of XIST/TSIX/PD-L1 regulation ENSG00000198793 PMC4420606__F8 TLR3/TRIF mainly regulates IL-32-mediated pro-inflammatory cytokine and IFNB secretion through activation of RIP-1 and TRAF family proteins ENSG00000183735 ENSG00000056558 ENSG00000131323 ENSG00000127191 ENSG00000276561 ENSG00000164342 PMC4792590__F4 Radiation and SN38 treatments modulate the expression of microRNAs, cytokines and chemokines in colon cancer cells in a p53-directed manner ENSG00000132906 ENSG00000002330 ENSG00000134982 ENSG00000095002 ENSG00000164305 PMC8003462__F1 Physiological functions of the various kinases included in the PKR/p38/RIPK1 pathway ENSG00000144895 ENSG00000137275 PMC2929244__F6 Defects in physiologically driven actin signaling at hippocampal synapses in Fmr1-KO mice ENSG00000291971 PMC4956564__F2 NFKB-mediated regulation of inflammatory and immunosuppressive CD4+ T-cell lineages ENSG00000104856 ENSG00000187796 ENSG00000102871 ENSG00000049768 ENSG00000127191 ENSG00000168610 ENSG00000138378 ENSG00000111537 ENSG00000077150 ENSG00000162676 ENSG00000156127 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000104432 ENSG00000073861 ENSG00000198286 PMC4696186__F2 Molecular mechanisms linking ciliogenesis and cell cycle regulation ENSG00000094631 ENSG00000112977 ENSG00000117650 ENSG00000137601 ENSG00000186638 ENSG00000007047 ENSG00000148384 ENSG00000166851 PMC7397409__F1 ERS and unfolded protein response (UPR) ENSG00000128272 PMC3340722__F2 TNF related apoptosis-inducing ligand and its receptors in ocular tumors ENSG00000168040 PMC6203150__F1 Regulation and downstream effects of the Akt signaling pathway ENSG00000002330 ENSG00000198793 PMC9392983__F7 miR-212-3p attenuates neuroinflammation of rats with Alzheimer’s disease via regulating the SP1/BACE1/NLRP3/Caspase-1 signaling pathway ENSG00000162711 ENSG00000185591 PMC3313452__F4 The noncanonical NFKB pathway ENSG00000104856 ENSG00000131323 ENSG00000127191 PMC8007363__F7 Smad3-NOX4-derived ROS-mediated p38MAPK/Akt signaling in TGFB1-induced ECM production of HBSMCs ENSG00000086991 ENSG00000062485 PMC2789488__F3 Schema of major signaling pathways involved in renal development (for space and clarity, not all factors in each pathway shown) ENSG00000106571 ENSG00000135253 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC10305525__F2 Three major H2S synthesis pathways are of enzymatic, non-enzymatic, and gut microbial origin PMC2880522__F1 Results of a Pathway Studio® analysis of direct relationships between the components of the protein-bound fraction of renal cyst fluid ENSG00000186395 ENSG00000167768 ENSG00000117601 ENSG00000145192 ENSG00000122194 ENSG00000171560 ENSG00000163631 PMC5730494__F6 Integration of signaling changes after the induction of BP1 ENSG00000122966 ENSG00000137440 PMC11621238__F4 Mitochondrial dynamics and mitophagy in GBM cells ENSG00000118508 ENSG00000099968 ENSG00000196550 ENSG00000116688 ENSG00000158828 ENSG00000136826 ENSG00000171109 PMC5388765__F1 An integrated network for phenylpropanoid regulation in the grape berry ENSG00000105722 ENSG00000205221 PMC3194179__F4 Ingenuity Pathway Analysis identified NFKB as the Top Network signaling Hub where the shaded shapes indicate the candidate genes from the present study ENSG00000123240 ENSG00000169862 ENSG00000113140 ENSG00000185760 ENSG00000112530 ENSG00000080709 ENSG00000106100 ENSG00000126458 ENSG00000137764 PMC3133912__F8 Bhlhb5 and the Notch signaling pathway ENSG00000109851 ENSG00000205927 ENSG00000164690 ENSG00000106003 PMC3194179__F2 Ingenuity Pathway Analysis identified ERK as the Top network signaling Hub where the shaded shapes indicate the candidate genes from the present study ENSG00000198561 ENSG00000128268 ENSG00000178473 PMC11825806__F7 Schematic diagram illustrating the effects of targeted activation of ErbB4 receptor on neuronal aging via ferroptosis inhibition ENSG00000151012 ENSG00000167468 ENSG00000178568 PMC3194179__F3 Ingenuity Pathway Analysis identified MapK as second Top network signaling Hub where the shaded shapes indicate the candidate genes from current study ENSG00000071564 ENSG00000140262 ENSG00000197746 ENSG00000053254 ENSG00000196092 ENSG00000154310 ENSG00000196220 ENSG00000185477 ENSG00000070019 PMC8529041__F7 Cancer Cell-Derived Exosomes Promote HCC Tumorigenesis Through Hedgehog Pathway ENSG00000164690 PMC9492373__F9 Atractylenolide III Attenuates Apoptosis in H9c2 Cells by Inhibiting Endoplasmic Reticulum Stress through the GRP78/PERK/CHOP Signaling Pathway ENSG00000128272 ENSG00000184743 PMC9201060__F7 Anti-Müllerian Hormone Signal Transduction involved in Müllerian Duct Regression ENSG00000180210 ENSG00000104899 ENSG00000170365 ENSG00000087245 ENSG00000154764 ENSG00000156076 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000135409 ENSG00000120057 ENSG00000168036 PMC4773560__F1 Mathematical model of adrenal steroidogenesis in NCI-H295R cells ENSG00000203859 PMC5412458__F2 Ubiquitylating enzymes and deubiquitylating enzymes (DUBs) govern the outcome of TGFB signaling ENSG00000135655 ENSG00000137834 ENSG00000175104 ENSG00000076604 PMC3417348__F8 Proposed role of ER calcium underlying early disruptions in synaptic homeostasis at the CA3–CA1 synapse in AD ENSG00000164879 ENSG00000198626 PMC4090103__F2 Virulence Strategies of the Dominant USA300 Lineage of Community Associated Methicillin Resistant Staphylococcus aureus (CA-MRSA) ENSG00000198576 ENSG00000118520 ENSG00000072195 PMC4272565__F6 Breast cancer pathway ENSG00000077935 ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000178999 ENSG00000197299 ENSG00000250506 PMC9201060__F1 Anti-Müllerian Hormone Signal Transduction involved in Müllerian Duct Regression ENSG00000104899 ENSG00000170365 ENSG00000135409 PMC8461076__F7 Effect of MAP3K8 on Prognosis and Tumor-Related Inflammation in Renal Clear Cell Carcinoma ENSG00000157404 ENSG00000186575 ENSG00000151657 ENSG00000111837 ENSG00000148175 PMC5826318__F1 Host-secreated miRNAs regulate the gut microbiota that in turn affects the host via induction of specific miRNAs ENSG00000160179 ENSG00000171791 ENSG00000168610 PMC4063414__F3 Phosphoglycerate mutase 1 (PGAM1) controls the levels of allosteric regulators 3-phosphoglycerate and 2-phosphoglycerate ENSG00000153574 ENSG00000135069 ENSG00000146733 PMC10943178__F10 The effects of EC‐EVs in sepsis‐related ALI/ARDS ENSG00000162692 ENSG00000115232 PMC9635865__F1 Recent advances in postoperative pulmonary rehabilitation of patients with non-small cell lung cancer (Review) ENSG00000164362 ENSG00000168036 ENSG00000100985 ENSG00000121879 ENSG00000277641 PMC2433332__F3 T-cell polarizing factors ENSG00000213658 ENSG00000105397 ENSG00000105639 ENSG00000168610 PMC5828008__F6 Oligodendrocyte Nf1 Controls Aberrant Notch Activation and Regulates Myelin Structure and Behavior ENSG00000013297 ENSG00000196712 PMC11172800__F3 Significantly, DE genes (identified by KEGG) were involved in the bacterial invasion of epithelial cells signaling pathway during 8-week S ENSG00000169291 ENSG00000070831 ENSG00000197959 ENSG00000163914 ENSG00000198087 ENSG00000015285 ENSG00000162704 ENSG00000150093 ENSG00000171608 PMC7933196__F1 Berberine on diseases by regulating intestinal flora ENSG00000135218 ENSG00000170458 ENSG00000172936 ENSG00000136869 PMC5685854__F7 Pathway of VEGFR-2 (produced using the Pathway Builder Tool) ENSG00000291971 ENSG00000112715 ENSG00000089159 ENSG00000150630 PMC9139317__F5 Mutational Activation of the NRF2 Pathway Upregulates Kynureninase Resulting in Tumor Immunosuppression and Poor Outcome in Lung Adenocarcinoma ENSG00000183077 ENSG00000188676 PMC8138777__F1 Breaking androgen receptor addiction of prostate cancer by targeting different functional domains in the treatment of advanced disease ENSG00000110721 ENSG00000184012 PMC3908331__F9 KEGG mapping for cell cycle pathway ENSG00000117400 ENSG00000132646 ENSG00000172005 ENSG00000123374 ENSG00000166278 PMC3868844__F6 Proposed signaling network involving mTORC2 and the p38 pathway ENSG00000115415 ENSG00000170214 ENSG00000198793 ENSG00000111713 ENSG00000284161 ENSG00000155792 ENSG00000100219 ENSG00000123268 ENSG00000266964 ENSG00000101974 PMC2988877__F2 DNA Damage Response: Making it safe to play with knives ENSG00000149311 ENSG00000175054 ENSG00000197299 PMC6460326__F1 HPV16 endocytosis and trafficking to multivesicular bodies ENSG00000135404 PMC9167958__F7 Temperature and Growth Selection Effects on Proliferation, Differentiation, and Adipogenic Potential of Turkey Myogenic Satellite Cells Through Frizzled-7-Mediated Wnt Planar Cell Polarity Pathway ENSG00000155760 PMC2988877__F3 The DNA Damage Response: Making it safe to play with knives ENSG00000175054 ENSG00000132646 ENSG00000197299 PMC8534027__F2 Roles of Diacylglycerol Kinase A in Cancer Cell Proliferation and Apoptosis ENSG00000065357 ENSG00000198793 PMC5397843__F1 Novel interactions of the von Hippel-Lindau (pVHL) tumor suppressor with the CDKN1 family of cell cycle inhibitors ENSG00000112576 ENSG00000005339 ENSG00000124762 ENSG00000145604 ENSG00000134086 ENSG00000129757 ENSG00000150991 ENSG00000135446 ENSG00000132646 ENSG00000123374 ENSG00000105810 ENSG00000116030 ENSG00000198625 PMC3683050__F11 Distinctive Profile of IsomiR Expression and Novel MicroRNAs in Rat Heart Left Ventricle ENSG00000104626 ENSG00000087095 ENSG00000166349 ENSG00000177606 ENSG00000130159 ENSG00000127191 ENSG00000026103 PMC6921025__F1 Overview of PI3K-AKT signaling pathway ENSG00000198793 ENSG00000184661 ENSG00000164327 ENSG00000099942 PMC4568771__F1 The Wnt/Beta-catenin signaling pathway and the oncology-indication drug candidates discussed in the paper ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC2215765__F1 Schematic overview of the LPS TLR4 signaling pathway ENSG00000170458 ENSG00000125538 ENSG00000172936 PMC7227439__F1 Role of metformin in VSMCs dysfunction ENSG00000145604 ENSG00000198793 ENSG00000163565 PMC4653031__F7 Insulin-like growth factor binding protein 5 (IGFBP5) functions as a tumor suppressor in human melanoma cells ENSG00000115461 ENSG00000140443 PMC8933845__F1 Immune Underpinnings of Barrett’s-Associated Adenocarcinogenesis: a Retrial of Nefarious Immunologic Co-Conspirators ENSG00000115008 ENSG00000101255 ENSG00000125538 ENSG00000128342 PMC10866932__F7 SALL4 promotes cancer stem-like cell phenotype and radioresistance in oral squamous cell carcinomas via methyltransferase-like 3-mediated m6A modification ENSG00000101115 ENSG00000026508 ENSG00000168036 ENSG00000165819 PMC7563239__F1 Possible mode of action of matrikines on pulmonary arterial endothelial cells ENSG00000198793 ENSG00000168040 ENSG00000026103 PMC2258259__F1 Metabolic pathways involved in pyrimidine metabolism ENSG00000228716 ENSG00000143179 ENSG00000102967 PMC11817128__F6 Target protein involved in NGF-NTRK1 signal transduction controls key protein targets PMC7376370__F8 Proposed mechanism and pathway of RUT in suppressing DSS-induced IBD in mice ENSG00000178573 PMC10487967__F2 CGAS–STING pathway in cell death, autophagy, and senescence ENSG00000183735 ENSG00000164430 ENSG00000168404 PMC3688698__F3 The mTOR Pathway in Hepatic Malignancies ENSG00000198793 PMC10487967__F3 Different roles of the cGAS–STING pathway in host defense and various diseases ENSG00000164430 ENSG00000122218 ENSG00000177606 PMC7545119__F1 Diagram of substrate utilization and suspected pathways in BAT ENSG00000143158 ENSG00000135218 ENSG00000169710 ENSG00000160785 ENSG00000062282 ENSG00000060762 PMC3764828__F5 Model depicting mitochondrial generation of H2O2 as a key modulator of TCR-mediated signal transduction ENSG00000291603 ENSG00000213658 ENSG00000134982 ENSG00000124181 PMC6724002__F6 Schematic representation a proposed pathway for hispidin-induced Nrf2/ARE-mediated cytoprotective proteins ENSG00000181019 ENSG00000023909 PMC7216777__F1 Metabolic processing of bioactive lipids and their role in host immune response to infection PMC6591114__F1 Ze brafish as a model system to delineate the role of heme and iron metabolism during erythropoiesis ENSG00000182511 ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000158578 ENSG00000188690 ENSG00000115107 PMC3026990__F5 Signaling networks associated with PPARD and inflammatory and invasive gene expression ENSG00000132906 ENSG00000262406 ENSG00000087245 ENSG00000104365 ENSG00000081041 ENSG00000070831 ENSG00000188404 ENSG00000124875 ENSG00000100985 ENSG00000005381 ENSG00000146648 ENSG00000164305 PMC5696077__F3 Biosynthesis and Structure-Activity Relationships of the Lipid A Family of Glycolipids ENSG00000162711 ENSG00000115415 ENSG00000172936 ENSG00000150455 ENSG00000142166 PMC9598565__F3 Postnatal Conditional Deletion of Bcl11b in Striatal Projection Neurons Mimics the Transcriptional Signature of Huntington’s Disease ENSG00000231247 ENSG00000005339 ENSG00000152495 ENSG00000130643 ENSG00000177425 PMC4970297__F6 Model summarizing the role of the HH signalling pathway and its primary transducer, GLI2, during mES cell cardiomyogenesis ENSG00000166823 ENSG00000106571 ENSG00000285109 ENSG00000183072 ENSG00000138606 ENSG00000128602 ENSG00000081189 ENSG00000089225 PMC5552241__F6 Proposed model of the Src/IGF-IR signaling axis present in both prostate cancer Exo and cells ENSG00000291971 PMC8245769__F1 Nature's marvels endowed in gaseous molecules I: Carbon monoxide and its physiological and therapeutic roles ENSG00000132326 PMC3713161__F7 Summary of the effects of increased dietary fat plus ethanol on the AMPK pathway and expression of enzymes involved in fatty acid synthesis ENSG00000131473 ENSG00000010704 PMC4514171__F1 TLR diversity, ligands, and signaling ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC9630107__F3 Glucose metabolism proteins regulated by Src ENSG00000180210 ENSG00000291971 ENSG00000010810 ENSG00000159399 PMC3737583__F8 Working model for how ERA may modulate signaling by TLR-activated DCs ENSG00000162594 ENSG00000125538 ENSG00000154059 PMC12114427__F2 Inducible expression pathway of Viperin ENSG00000088888 ENSG00000125347 ENSG00000276561 ENSG00000142166 PMC9419932__F4 Estrogen Signaling Dictates Musculoskeletal Stem Cell Behavior: Sex Differences in Tissue Repair ENSG00000157554 ENSG00000146648 PMC9472457__F2 Genetic and immunologic evaluation of children with inborn errors of immunity and severe or critical COVID-19 ENSG00000162711 ENSG00000213928 ENSG00000167207 ENSG00000119669 ENSG00000274571 ENSG00000276561 ENSG00000137080 ENSG00000183735 ENSG00000105612 ENSG00000111537 ENSG00000164430 ENSG00000088888 ENSG00000184012 ENSG00000136869 ENSG00000172936 ENSG00000164342 PMC5706812__F10 Dysregulated lncRNA-UCA1 contributes to the progression of gastric cancer through regulation of the PI3K-Akt-mTOR signaling pathway ENSG00000117020 ENSG00000198793 PMC7686960__F6 Proposed model showing the suppressive mechanisms of Maackiain in RANKL‐activated NF‐KB and NFATc1 signalling pathways ENSG00000102575 ENSG00000100985 ENSG00000131196 ENSG00000143387 PMC9168169__F2 Advances in the study of RNA-binding proteins in diabetic complications ENSG00000162711 ENSG00000165119 ENSG00000130522 ENSG00000116688 ENSG00000125538 ENSG00000198793 ENSG00000139515 ENSG00000186480 ENSG00000215301 ENSG00000057663 PMC3436188__F8 Interaction between Ryk and Wnt signaling pathways ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC3875403__F6 MDA-7 interferes with tumor promoting pathways ENSG00000105723 PMC4230782__F9 The role of Pkp3 in cell–cell junction formation ENSG00000184363 ENSG00000057294 PMC8766833__F9 Quercetin Attenuates Podocyte Apoptosis of Diabetic Nephropathy Through Targeting EGFR Signaling ENSG00000146648 PMC8412840__F2 TGFB2 in cartilage development and diseases ENSG00000139219 ENSG00000100234 ENSG00000170365 PMC9027975__F2 Interplay between Viruses and Host DNA Sensors ENSG00000134070 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC11920683__F10 Schematic showing genes upregulated by ibudilast treatment during NMDA retinal damage on scRNA‐seq analysis ENSG00000101407 ENSG00000177169 ENSG00000106070 ENSG00000198793 ENSG00000163914 ENSG00000169047 ENSG00000145979 ENSG00000118515 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC9027975__F5 Interplay between Viruses and Host DNA Sensors ENSG00000183735 ENSG00000163565 PMC5345336__F4 Notch signaling pathway ENSG00000128917 ENSG00000184916 ENSG00000090932 PMC8125679__F2 More Than Meets the Eye: Scientific Rationale behind Molecular Imaging and Therapeutic Targeting of Prostate-Specific Membrane Antigen (PSMA) in Metastatic Prostate Cancer and Beyond ENSG00000285438 ENSG00000140443 PMC3398238__F7 A ubiquitin-binding protein FAAP20 links RNF8-mediated ubiquitination to the Fanconi anemia DNA Repair network ENSG00000131944 ENSG00000175054 ENSG00000144554 ENSG00000187790 ENSG00000112130 PMC5769420__F4 Aurora kinase A and aurora kinase B interact with oncogenes to initiate tumorigenesis ENSG00000012048 ENSG00000006451 ENSG00000087586 PMC8820871__F4 Mechanistic Insights of Qingre Jiedu Recipe Based on Network Pharmacology Approach against Heart Failure ENSG00000101751 ENSG00000002330 ENSG00000179091 ENSG00000172005 ENSG00000111816 PMC4258904__F2 Plasmacytoid dendritic cell as the Swiss army knife of the immune system: Molecular regulation of their multifaceted functions ENSG00000089692 ENSG00000239732 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000166886 ENSG00000276561 ENSG00000184216 ENSG00000010671 PMC4841296__F1 Main molecular mechanisms affected in malignant megakaryopoiesis and platelet function defects ENSG00000151702 ENSG00000102145 ENSG00000169704 ENSG00000159216 ENSG00000117400 ENSG00000100345 ENSG00000101162 PMC2610259__F1 Chronic colon colitis model ENSG00000181019 ENSG00000175793 ENSG00000178573 ENSG00000079999 PMC7014825__F6 JNK1-dependent IL-17 and TGFB signaling ENSG00000163739 ENSG00000163702 PMC6466002__F2 Duck RIG-I-like receptor (RLR) family signaling pathway ENSG00000088888 ENSG00000135114 ENSG00000121060 ENSG00000276561 PMC4629002__F4 Networks predicted by Ingenuity Pathway Analysis in Cmah-null mice ENSG00000036672 ENSG00000159388 ENSG00000291803 ENSG00000072274 ENSG00000158578 ENSG00000099377 ENSG00000131781 ENSG00000070669 ENSG00000106546 ENSG00000292366 ENSG00000114349 ENSG00000184164 ENSG00000170522 ENSG00000159674 ENSG00000115457 ENSG00000184524 ENSG00000078747 ENSG00000049239 ENSG00000165458 ENSG00000163914 ENSG00000116679 ENSG00000118515 ENSG00000165953 ENSG00000132326 ENSG00000143333 ENSG00000113790 ENSG00000140443 ENSG00000291479 ENSG00000111249 ENSG00000110711 ENSG00000104365 ENSG00000167323 ENSG00000103375 ENSG00000105697 ENSG00000151365 ENSG00000102802 ENSG00000108510 ENSG00000132170 ENSG00000167772 ENSG00000173757 ENSG00000161533 ENSG00000079435 ENSG00000116661 ENSG00000067048 ENSG00000123689 ENSG00000114115 PMC9292703__F1 Tryptophan‐derived serotonin‐kynurenine balance in immune activation and intestinal inflammation PMC10931026__F1 The polyamine synthesis pathway ENSG00000088826 ENSG00000148832 ENSG00000123505 ENSG00000116649 ENSG00000102172 PMC8866876__F4 Nrf2 Pathway in Liver Diseases ENSG00000181019 ENSG00000175793 ENSG00000130649 ENSG00000284099 ENSG00000079999 PMC8866876__F1 Nrf2 Pathway in Liver Diseases ENSG00000100387 ENSG00000079999 PMC6116371__F3 CircRNA and cancer-associated signaling pathways ENSG00000143379 ENSG00000168610 ENSG00000146648 PMC4620040__F1 Inflammatory bowel disease (IBD) as a multifactorial disorder ENSG00000162711 ENSG00000274429 ENSG00000167207 ENSG00000187796 ENSG00000179914 ENSG00000197375 ENSG00000145777 ENSG00000237693 ENSG00000243509 ENSG00000168610 ENSG00000115607 ENSG00000162594 ENSG00000158473 ENSG00000118503 ENSG00000187908 ENSG00000136869 ENSG00000100219 ENSG00000113302 ENSG00000112486 PMC8674839__F2 Calcium Ions Aggravate Alzheimer’s Disease Through the Aberrant Activation of Neuronal Networks, Leading to Synaptic and Cognitive Deficits ENSG00000144935 ENSG00000167323 ENSG00000198838 ENSG00000293604 ENSG00000198626 PMC4191659__F2 Receptor “hijacking” by malignant glioma cells: a tactic for tumor progression ENSG00000291971 ENSG00000138798 ENSG00000169429 ENSG00000171791 ENSG00000168610 ENSG00000146648 PMC4470795__F1 Grade-dependent metabolic reprogramming in kidney cancer revealed by combined proteomics and metabolomics analysis ENSG00000074800 ENSG00000173599 ENSG00000136872 PMC9272348__F3 Molecular signaling pathway targeted therapeutic potential of thymoquinone in Alzheimer’s disease ENSG00000087085 PMC3640280__F5 A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance ENSG00000198793 PMC7380956__F1 Accessory pathways of glucose metabolism: ENSG00000092621 ENSG00000173402 ENSG00000181027 PMC3429879__F1 Therapeutic Mechanisms of Treatment in Cervical and Vaginal Cancer ENSG00000291814 ENSG00000167900 PMC3641842__F1 The complement system ENSG00000039537 ENSG00000113600 ENSG00000291559 ENSG00000197971 ENSG00000203710 ENSG00000196352 ENSG00000117335 ENSG00000244731 ENSG00000166278 ENSG00000236625 PMC5887227__F9 ScRNA-seq profiling on progenitor cells and hPSCs ENSG00000087510 ENSG00000113196 ENSG00000162493 ENSG00000156574 ENSG00000135903 ENSG00000135111 ENSG00000081051 ENSG00000081189 ENSG00000105894 ENSG00000043355 ENSG00000103449 ENSG00000116132 ENSG00000105991 ENSG00000128052 ENSG00000137203 ENSG00000019549 ENSG00000272398 ENSG00000288297 ENSG00000150347 ENSG00000113722 ENSG00000174059 ENSG00000184344 ENSG00000125968 PMC6345546__F1 Mechanisms of translation initiation currently known ENSG00000163435 ENSG00000100353 PMC8268428__F2 Janus Face of IL-33 Signaling in Tumor Development and Immune Escape ENSG00000137033 ENSG00000109321 ENSG00000123374 ENSG00000172936 ENSG00000185187 ENSG00000175104 ENSG00000184216 PMC8650690__F6 Aronia Upregulates Myogenic Differentiation and Augments Muscle Mass and Function Through Muscle Metabolism ENSG00000198793 PMC4011666__F7 Calcineurin Signaling Regulates Neural Induction Through Antagonizing the BMP Pathway ENSG00000170365 PMC9570443__F1 Pyroptosis and Insulin Resistance in Metabolic Organs ENSG00000278718 ENSG00000162711 PMC3502876__F1 Reactive oxygen species-mediated autophagy regulation ENSG00000149311 ENSG00000177169 ENSG00000198382 ENSG00000083290 ENSG00000198793 ENSG00000155792 ENSG00000189403 ENSG00000167965 ENSG00000145782 ENSG00000057663 PMC7875152__F2 Genetic causes of PH ENSG00000006071 ENSG00000164736 ENSG00000139567 ENSG00000133657 ENSG00000121075 ENSG00000204217 ENSG00000163217 ENSG00000171303 PMC8833412__F1 New Insights on the Genetics of Pheochromocytoma and Paraganglioma and Its Clinical Implications ENSG00000135956 ENSG00000073578 ENSG00000117118 ENSG00000196782 ENSG00000143252 ENSG00000153208 ENSG00000134086 ENSG00000120868 ENSG00000077782 ENSG00000269858 ENSG00000146701 ENSG00000009307 ENSG00000196712 ENSG00000167985 ENSG00000062485 PMC3518467__F1 Fast, Potent Pharmacological Expansion of Endogenous Hes3+/Sox2+ Cells in the Adult Mouse and Rat Hippocampus ENSG00000173673 ENSG00000198793 ENSG00000131095 ENSG00000168610 PMC3731517__F6 Hepatic cholesterol synthesis and catabolism enzymes, uptake receptors, BA transport systems, phase II detoxification enzymes, and nuclear receptors investigated in this study ENSG00000130164 ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC6038278__F1 Dysregulated genes and associated miRNAs in the KEGG TGFBeta-signaling pathway ENSG00000111537 ENSG00000095739 ENSG00000100387 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000185591 PMC4264883__F4 Downstream Targets of Lmo4 Are Modulated by Cisplatin in the Inner Ear of Wistar Rats ENSG00000012048 ENSG00000105397 ENSG00000115415 ENSG00000143013 ENSG00000171791 ENSG00000074771 ENSG00000168610 PMC6038278__F2 MiRNA-mRNA associations involving genes in the KEGG TGFBeta-Signaling Pathway by location of action: extracellular factors (a), membrane receptors (b), and nuclear factors (c) ENSG00000198176 ENSG00000136997 ENSG00000118707 ENSG00000133740 ENSG00000080839 ENSG00000137801 PMC2733081__F4 MAPK Signaling Cascade is a Central Hub in the Regulation of Cell Cycle, Apoptosis and Cytoskeleton Remodeling by Tripeptidyl-Peptidase II ENSG00000177189 ENSG00000139269 ENSG00000136997 ENSG00000091409 ENSG00000205250 PMC5137308__F7 Molecular mechanism for neurogenesis activated by 5-HT4 receptors by MOS ENSG00000136158 ENSG00000066735 ENSG00000172680 ENSG00000070831 ENSG00000163914 PMC9305276__F4 Signaling mechanisms of SARS-CoV-2 Nucleocapsid protein in viral infection, cell death and inflammation ENSG00000162711 ENSG00000088888 ENSG00000125538 PMC3531289__F1 Chapter 3: Small Molecules and Disease ENSG00000165983 ENSG00000181026 PMC8866876__F5 Nrf2 Pathway in Liver Diseases ENSG00000175793 ENSG00000130649 ENSG00000277943 ENSG00000079999 PMC6321527__F5 Hypothesized mechanism of S5-induced death of human melanoma A375 cells ENSG00000134057 ENSG00000146648 PMC5141361__F3 Details of the PMF network model showing deregulated miRNAs and genes that participates to specific connected pathways, linked in turn to biological processes and functions germane to the disease ENSG00000005339 ENSG00000099812 ENSG00000198793 ENSG00000101280 ENSG00000196914 PMC3159301__F1 Pathways involved in platelet hyperreactivity in DM patients and therapeutic targets ENSG00000169047 ENSG00000145321 PMC8009526__F1 Signaling networks in inflammatory pathways and risk for suicidal behavior ENSG00000077150 ENSG00000090402 ENSG00000172216 ENSG00000109320 ENSG00000125538 ENSG00000177606 ENSG00000168610 PMC7487062__F4 MDA-9/Syntenin/SDCBP: New insights into a unique multifunctional scaffold protein ENSG00000087245 ENSG00000070831 ENSG00000115457 ENSG00000291971 ENSG00000168036 ENSG00000100985 ENSG00000112715 ENSG00000168610 ENSG00000146648 PMC4607655__F3 Metaproteomics Reveals Functional Shifts in Microbial and Human Proteins During a Preterm Infant Gut Colonization Case ENSG00000147044 ENSG00000130545 ENSG00000156299 ENSG00000168036 ENSG00000143375 PMC5283709__F3 A Concise Atlas of Thyroid Cancer Next-Generation Sequencing Panel ThyroSeq v.2 ENSG00000164362 ENSG00000166278 ENSG00000111816 PMC3789261__F3 Pathways impinging specifically on glucose-mediated F-actin remodeling in the B cell ENSG00000070831 ENSG00000149269 ENSG00000220205 PMC2858906__F1 Main steps and key regulators in blood and lymphatic vasculature development ENSG00000105672 ENSG00000117707 ENSG00000203883 PMC7920857__F8 Mechanism graph of the regulatory network and function of SIRT1 in aging of HEMECsSIRT1 restrains cell aging through GIRDIN phosphorylation via Akt signaling pathway ENSG00000096717 PMC11629350__F6 Neural graph network displaying the six signaling pathways that were detected as significantly regulated, along with the genes within these pathways that were significantly affected by mechanical loading (0 ENSG00000156232 ENSG00000104880 ENSG00000288174 ENSG00000067191 ENSG00000196498 ENSG00000165269 PMC8650620__F2 In Sickness and in Health: The Oxygen Reactive Species and the Bone ENSG00000152266 ENSG00000086991 ENSG00000168036 PMC8426635__F7 Tricin Biosynthesis and Bioengineering ENSG00000105227 ENSG00000084774 PMC5480057__F4 Extended regulatory network to describe Nanog multistable dynamics in serum/LIF ENSG00000119715 ENSG00000136826 PMC6539579__F5 Roles of c-Myc in colorectal cancer (CRC) organoids ENSG00000103888 PMC6539579__F3 Regulation of Wnt/Beta-catenin/c-Myc signaling pathway ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC5354887__F7 Concomitant inhibition of receptor tyrosine kinases and downstream AKT synergistically inhibited growth of KRAS/BRAF mutant colorectal cancer cells ENSG00000157764 ENSG00000169047 PMC11783064__F3 Molecular-signalling pathways activated by methamphetamine contribute to cardiotoxicity ENSG00000146399 ENSG00000171791 ENSG00000079999 ENSG00000214253 PMC12065022__F7 Working model for the mechanism of quercetin on HCC ENSG00000198793 PMC9672399__F5 Tridimensional cell culture of dermal fibroblasts promotes exosome-mediated secretion of extracellular matrix proteins ENSG00000049323 ENSG00000171246 ENSG00000145681 ENSG00000181163 ENSG00000102359 ENSG00000169710 ENSG00000244731 ENSG00000120885 ENSG00000087303 ENSG00000104332 ENSG00000236625 ENSG00000126218 ENSG00000274619 ENSG00000130164 ENSG00000074181 ENSG00000157227 ENSG00000038427 ENSG00000141753 ENSG00000263238 ENSG00000123610 ENSG00000131473 ENSG00000189058 ENSG00000142192 ENSG00000143549 ENSG00000115318 ENSG00000165119 ENSG00000138131 ENSG00000162745 ENSG00000164694 ENSG00000189056 ENSG00000113140 ENSG00000151655 ENSG00000273686 ENSG00000163661 ENSG00000173546 ENSG00000117122 ENSG00000129038 ENSG00000148702 ENSG00000184371 ENSG00000188783 PMC6371621__F1 The mechanisms of microRNA biogenesis and its regulation of gene expression ENSG00000092847 ENSG00000128191 ENSG00000113360 ENSG00000134698 ENSG00000123908 ENSG00000132341 PMC7554303__F2 Various cell fates upon Mycobacterium tuberculosis infection ENSG00000135218 ENSG00000102871 ENSG00000125538 ENSG00000168040 PMC8106603__F2 Crosstalk between endoplasmic reticulum stress and oxidative stress: a dynamic duo in multiple myeloma ENSG00000144895 ENSG00000116688 ENSG00000100219 ENSG00000171109 PMC10539095__F2 Molecular Basis of Wnt/Beta-Catenin Signaling Pathways in Neurodegenerative Diseases ENSG00000180210 ENSG00000100592 ENSG00000163914 PMC8955937__F9 WWOX/HIF1A Axis Downregulation Alters Glucose Metabolism and Predispose to Metabolic Disorders ENSG00000159399 ENSG00000062485 PMC8700745__F3 Alterations in SLC4A2, SLC26A7 and SLC26A9 Drive Acid–Base Imbalance in Gastric Neuroendocrine Tumors and Uncover a Novel Mechanism for a Co-Occurring Polyautoimmune Scenario ENSG00000152266 ENSG00000205221 ENSG00000147606 ENSG00000144407 ENSG00000173599 ENSG00000157005 PMC3607103__F3 Recognition of nucleic acids by innate immune cells triggers cytokine production ENSG00000239732 ENSG00000088888 ENSG00000163568 ENSG00000186716 ENSG00000172936 ENSG00000276561 PMC3284544__F4 Global Gene Expression and Systems Biology Analysis of Bovine Monocyte-Derived Macrophages in Response to In Vitro Challenge with Mycobacterium bovis ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC3284544__F5 Global Gene Expression and Systems Biology Analysis of Bovine Monocyte-Derived Macrophages in Response to In Vitro Challenge with Mycobacterium bovis ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000115317 PMC8941124__F7 Dynamical modeling of miR-34a, miR-449a, and miR-16 reveals numerous DDR signaling pathways regulating senescence, autophagy, and apoptosis in HeLa cells ENSG00000149311 ENSG00000177169 ENSG00000168283 ENSG00000175115 ENSG00000136997 ENSG00000171791 ENSG00000136048 PMC8572597__F7 Exploring the Effect of Jiawei Buguzhi Pills on TGF-Beta-Smad Pathway in Postmenopausal Osteoporosis Based on Integrated Pharmacological Strategy ENSG00000095739 ENSG00000187720 ENSG00000198742 ENSG00000163914 ENSG00000156574 ENSG00000134363 PMC9189138__F2 Biophysics Role and Biomimetic Culture Systems of ECM Stiffness in Cancer EMT ENSG00000142627 ENSG00000162733 ENSG00000105329 ENSG00000170558 ENSG00000163914 ENSG00000124766 ENSG00000146648 ENSG00000121966 PMC3284544__F6 Global Gene Expression and Systems Biology Analysis of Bovine Monocyte-Derived Macrophages in Response to In Vitro Challenge with Mycobacterium bovis ENSG00000088888 ENSG00000187608 ENSG00000184995 ENSG00000132478 ENSG00000276561 PMC6167446__F1 Pathogenic roles of NLRP3 inflammasome in liver diseases ENSG00000162711 ENSG00000125538 ENSG00000136869 ENSG00000265972 PMC10926276__F5 Quantitative proteomics reveals the protective effects of Yinchenzhufu decoction against cholestatic liver fibrosis in mice by inhibiting the PDGFRB/PI3K/AKT pathway ENSG00000124256 ENSG00000169896 ENSG00000173611 ENSG00000139496 ENSG00000213782 ENSG00000111450 ENSG00000084110 ENSG00000265972 ENSG00000099194 ENSG00000197045 ENSG00000070669 ENSG00000119048 ENSG00000137947 ENSG00000130202 ENSG00000166391 ENSG00000203859 ENSG00000137996 ENSG00000198125 ENSG00000136235 ENSG00000188612 ENSG00000084774 ENSG00000148965 PMC3849943__F2 Network of the interactions of the miRNAs and their target genes (experimental observed or highly predicted) ENSG00000134460 ENSG00000151490 ENSG00000111728 ENSG00000170558 ENSG00000120889 ENSG00000161955 ENSG00000150782 ENSG00000073060 ENSG00000157227 ENSG00000181847 ENSG00000291814 ENSG00000136997 ENSG00000136869 ENSG00000213809 ENSG00000171951 ENSG00000197635 ENSG00000137193 ENSG00000064547 ENSG00000004399 ENSG00000073756 ENSG00000131015 ENSG00000108691 ENSG00000118503 ENSG00000184371 ENSG00000049249 ENSG00000173334 PMC3513881__F3 Proposed three pathways for the mechanism of nicotinic acetylcholine receptor (nAChR)-mediated survival signal transduction ENSG00000010810 ENSG00000168610 PMC4545436__F1 Signaling pathways involved in CSCs ENSG00000134982 ENSG00000168036 ENSG00000164690 ENSG00000128602 ENSG00000281857 PMC4423147__F8 The Nodal signaling pathway during establishment of the LR asymmetry in amphioxus ENSG00000164379 ENSG00000155011 ENSG00000104371 ENSG00000156574 ENSG00000130283 ENSG00000184344 PMC3297581__F6 Tcf7 Is an Important Regulator of the Switch of Self-Renewal and Differentiation in a Multipotential Hematopoietic Cell Line ENSG00000151702 ENSG00000157554 ENSG00000245848 ENSG00000111145 ENSG00000159216 ENSG00000108924 ENSG00000177606 ENSG00000092067 ENSG00000162924 ENSG00000125347 ENSG00000168610 ENSG00000069667 PMC10540075__F8 Premature senescence and cardiovascular disease following cancer treatments: mechanistic insights ENSG00000105835 ENSG00000180773 ENSG00000123572 ENSG00000221955 ENSG00000278488 ENSG00000146477 ENSG00000157064 ENSG00000262217 ENSG00000103257 ENSG00000173614 ENSG00000008130 PMC7595283__F1 Some like it hot: Candida activation of inflammasomes ENSG00000162711 ENSG00000187796 ENSG00000125538 ENSG00000091106 ENSG00000146648 PMC6795182__F1 Cluster-1, cluster-2, and cluster-3, with molecular-targeted therapeutic options ENSG00000135956 ENSG00000134086 ENSG00000138798 ENSG00000169047 ENSG00000168036 ENSG00000196782 ENSG00000146701 ENSG00000146648 ENSG00000269858 ENSG00000009307 ENSG00000196712 PMC4599277__F7 Honokiol abrogates leptin-induced tumor progression by inhibiting Wnt1-MTA1-Beta-catenin signaling axis in a microRNA-34a dependent manner ENSG00000134982 ENSG00000168036 ENSG00000168610 ENSG00000125084 PMC6059011__F1 EV Biogenesis and Interaction With Recipient CellsExosome formation starts with endocytosis, a process in which the cell membrane is pinched inward and captures bioactive molecules, resulting in the formation of the endosome ENSG00000041353 ENSG00000168461 ENSG00000074319 ENSG00000165527 PMC8027612__F8 Protective effect of SAA on vascular permeability via inhibition of VEGFA-Src-MMP signaling pathway activation during acute ischemic stroke ENSG00000168036 ENSG00000112715 PMC4417677__F1 Cartoon illustration of the physiological roles and therapeutic implications of OCT1, SLC13A5 and ZnT8 in glucose metabolism, lipogenesis and insulin pathway ENSG00000042832 ENSG00000105953 ENSG00000141485 PMC8306901__F5 Molecular Pathology and Targeted Therapies for Personalized Management of Central Nervous System Germinoma ENSG00000157404 ENSG00000110395 ENSG00000005882 ENSG00000163599 ENSG00000198793 ENSG00000196712 PMC5416953__F5 Working model of the role of LXR in Fgf21 gene regulation in mouse liver during fasting ENSG00000101751 ENSG00000171720 ENSG00000166169 ENSG00000069667 PMC8215544__F4 Neddylation Regulates Macrophages and Implications for Cancer Therapy ENSG00000167513 PMC4658613__F6 Insulin-like growth factor-1 signaling with regard to Helicobacter pylori associated glucose dysregulation ENSG00000169047 ENSG00000140443 PMC11979393__F1 The apoptosis signaling pathway ENSG00000102871 ENSG00000171791 ENSG00000168040 ENSG00000127191 PMC10181312__F2 Circadian clock system involved in regulating photoperiodic flowering in Arabidopsis, soybean, and rice ENSG00000163435 ENSG00000163933 ENSG00000203783 ENSG00000186654 ENSG00000131188 PMC11853215__F7 Proposed simplified signaling pathway elucidating the mechanism underlying the amelioration of steatosis induced by Exendin-4 ENSG00000138823 ENSG00000115361 ENSG00000121966 ENSG00000026103 PMC4609261__F1A Mapping the pathways of resistance to targeted therapies ENSG00000198793 PMC5448109__F6 Simplified models of ribonucleotide excision repair in Eukarya (A), Archaea (B), and Bacteria (C) ENSG00000101751 ENSG00000132646 ENSG00000166169 PMC8106186__F1 Signalling pathways involved in CM, UM and MM oncogenesis, and regulation of HIF under hypoxia ENSG00000157404 ENSG00000157764 ENSG00000198793 ENSG00000121966 ENSG00000196712 PMC1913098__F1 Sensitivity Analysis of Intracellular Signaling Pathway Kinetics Predicts Targets for Stem Cell Fate Control ENSG00000128342 ENSG00000168610 PMC4470795__F4 Grade-dependent metabolic reprogramming in kidney cancer revealed by combined proteomics and metabolomics analysis ENSG00000135423 PMC3812980__F6 Proposed schema of how the BMP signaling axis limits neurogenic muscle wasting ENSG00000170365 PMC8293747__F1 Role and Mechanism of Pyroptosis and Potential Therapeutic Targets in Sepsis: A Review ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC8858079__F1 IGF cascade ENSG00000197081 ENSG00000169047 ENSG00000198793 ENSG00000171791 ENSG00000140443 PMC10964526__F8 Potential pathways of exercise training to improve pulmonary function ENSG00000198793 ENSG00000049768 ENSG00000136014 PMC4506786__F4 Linear ubiquitination signals in adaptive immune responses ENSG00000137275 ENSG00000102871 ENSG00000082512 ENSG00000083799 ENSG00000168040 ENSG00000154124 ENSG00000127191 PMC11849352__F1 TLR3 signaling pathway ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC11103046__F1 Cardioprotective Mechanisms of SGLT2 Inhibitors Against Cancer Treatment–Induced CardiotoxicitySodium-glucose cotransporter-2 (SGLT2) inhibitors protect against cardiovascular toxicity induced by anticancer drugs via multiple mechanisms ENSG00000162711 ENSG00000128272 ENSG00000181019 ENSG00000198793 PMC4506786__F1 Linear ubiquitination signals in adaptive immune responses ENSG00000102871 ENSG00000082512 ENSG00000083799 ENSG00000154124 ENSG00000127191 PMC9708627__F2 Interferon in systemic lupus erythematosus—A halfway between monogenic autoinflammatory and autoimmune disease PMC5563293__F2 Schematic presentation of the fusion-activated Ca2+ entry (FACE) ENSG00000293604 ENSG00000196839 ENSG00000010278 ENSG00000084774 PMC11103046__F2 The Anticancer Effects of SGLT2iSGLT2 inhibitors (SGLT2i) inhibit glucose uptake by inhibiting SGLTs (SGLT-1 and SGLT-2) and glucose transporters (GLUTs) ENSG00000165119 ENSG00000198793 ENSG00000129514 ENSG00000164690 ENSG00000146648 PMC3378547__F5 Molecular Effects of Doxycycline Treatment on Pterygium as Revealed by Massive Transcriptome Sequencing ENSG00000166794 ENSG00000134109 ENSG00000134910 ENSG00000120820 ENSG00000163902 ENSG00000165280 ENSG00000163479 ENSG00000173540 ENSG00000065485 ENSG00000128272 ENSG00000058262 ENSG00000119523 ENSG00000155660 ENSG00000100219 ENSG00000090520 PMC7554303__F3 Immunometabolic and bioenergetic changes in a macrophage infected with Mycobacterium tuberculosis ENSG00000169245 ENSG00000135218 ENSG00000168958 ENSG00000138755 ENSG00000113520 ENSG00000107485 ENSG00000172936 ENSG00000166278 ENSG00000105639 ENSG00000084774 PMC7226825__F2 Anti-inflammatory roles of GFLs and their receptors following air pollution, allergy, bacteria or virus infections ENSG00000105329 ENSG00000168546 ENSG00000158825 ENSG00000113520 ENSG00000005381 ENSG00000171119 ENSG00000117407 PMC3683875__F1 Nucleotide excision repair (NER) pathway ENSG00000012061 ENSG00000108582 ENSG00000132646 ENSG00000136936 PMC3670291__F2 Roles of STATs signaling in cardiovascular diseases ENSG00000291971 ENSG00000168610 PMC8145016__F2 Vitamin D Effects on Bone Homeostasis and Cardiovascular System in Patients with Chronic Kidney Disease and Renal Transplant Recipients ENSG00000118972 ENSG00000160867 PMC3008633__F1 Examples of reaction–diffusion processes in muscle ENSG00000041982 ENSG00000173599 ENSG00000198125 ENSG00000062485 PMC7555983__F6 MiRNAs, their related gene targets and cellular pathways likely involved in MFS aortopathy ENSG00000134982 ENSG00000145386 PMC7290605__F4 Schematic diagram represent the Putative mechanism of HPV in breast carcinogenesis ENSG00000012048 ENSG00000086102 ENSG00000291971 PMC7659352__F13 Co-treatment with coffee decoction and tamoxifen markedly induces apoptosis by activating p53 in MCF-7 cells ENSG00000082175 ENSG00000160182 ENSG00000196208 PMC6387651__F6 Proposed signaling pathways that regulate LSEC phenotype and crosstalk between LSECs and HSCs in normal and fibrotic liver ENSG00000281244 ENSG00000135218 ENSG00000113070 ENSG00000138798 ENSG00000146648 PMC4082184__F2 Turning Off AKT: PHLPP as a Drug Target ENSG00000169047 PMC3911663__F5 Summary model for rAdV DNA sensing ENSG00000239732 ENSG00000164430 ENSG00000163568 ENSG00000172936 ENSG00000276561 PMC9612852__F2 Intracellular checkpoint of IL-15 signaling in human or murine NK cells ENSG00000033327 ENSG00000150907 ENSG00000198793 ENSG00000100219 ENSG00000105639 ENSG00000168610 PMC8704600__F1 Crosstalk between Statins and Cancer Prevention and Therapy: An Update ENSG00000163914 ENSG00000171791 ENSG00000146648 PMC3727904__F2 PATHWAYS IN MICROBE-INDUCED OBESITY ENSG00000239732 ENSG00000111537 ENSG00000170458 ENSG00000187554 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000111321 ENSG00000131096 PMC4777532__F3 Network Analysis of Metabolite GWAS Hits: Implication of CPS1 and the Urea Cycle in Weight Maintenance ENSG00000228716 ENSG00000081181 ENSG00000065911 ENSG00000077522 ENSG00000145020 ENSG00000070669 ENSG00000120254 ENSG00000178445 ENSG00000108849 ENSG00000166337 ENSG00000072210 ENSG00000075461 ENSG00000197444 ENSG00000125686 ENSG00000220205 ENSG00000172482 ENSG00000118520 ENSG00000178922 ENSG00000091140 ENSG00000115419 ENSG00000196712 ENSG00000189056 ENSG00000132639 ENSG00000248487 ENSG00000156689 ENSG00000007171 ENSG00000116984 ENSG00000145414 ENSG00000172508 ENSG00000133433 ENSG00000066813 ENSG00000117862 ENSG00000069482 ENSG00000100596 ENSG00000101849 ENSG00000010810 ENSG00000179761 ENSG00000084774 PMC9314626__F2 Metabolic dynamics instruct CD8+ T‐cell differentiation and functions ENSG00000139514 ENSG00000134982 ENSG00000198793 ENSG00000136997 PMC7865543__F3 Signaling pathways involved in regulation of and therapeutic avenues for targeting the LOX family ENSG00000129038 ENSG00000134013 ENSG00000291971 ENSG00000168487 PMC10473154__F1 Understanding the Involvement of microRNAs in Mitochondrial Dysfunction and Their Role as Potential Biomarkers and Therapeutic Targets in Parkinson’s Disease ENSG00000116688 ENSG00000158828 ENSG00000171109 ENSG00000106459 PMC7263916__F4 Avian leukosis virus subgroup J and reticuloendotheliosis virus coinfection induced TRIM62 regulation of the actin cytoskeleton ENSG00000180210 ENSG00000042832 ENSG00000134982 ENSG00000138443 ENSG00000163914 ENSG00000089159 PMC8949402__F2 Immune Escape Mechanism and Vaccine Research Progress of African Swine Fever Virus ENSG00000164430 ENSG00000164342 PMC7187988__F2 Hormonal control of adipocyte lipolysis ENSG00000166819 ENSG00000168792 ENSG00000011198 ENSG00000169047 ENSG00000145321 ENSG00000177666 ENSG00000078098 PMC6780086__F6 Transcriptional profiling of enzymes involved in type II fatty acid synthesis (FASII), glycerolipid synthesis in plastid (GLSp) and cytosol glycolysis (GLSc), and beta-oxidation ENSG00000069482 ENSG00000042832 ENSG00000173599 ENSG00000026103 PMC5777172__F2 Regulation of hepatic glucose metabolism in health and disease ENSG00000171105 ENSG00000288269 PMC5729931__F5 Enhanced AMPA receptor trafficking mediates the anorexigenic effect of endogenous glucagon like peptide-1 in the paraventricular hypothalamus PMC5431987__F5 Ingenuity Pathway Analysis cancer network from RNA-Seq breast cancer samples ENSG00000169554 ENSG00000111859 ENSG00000146648 ENSG00000164305 PMC8369345__F1 Role for Frizzled and Their Post-Translational Modifications in the Mammalian Central Nervous System ENSG00000281324 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC12106438__F2 Molecular mechanisms of intracellular lactate production and export ENSG00000115419 PMC12106438__F3 Effects and mechanisms of lactate on macrophage polarization ENSG00000189403 ENSG00000118520 ENSG00000159399 ENSG00000060762 PMC3379693__F1 Role of innate immunity and the microbiota in liver fibrosis: crosstalk between the liver and gut ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC7187988__F5 Adipocyte lipolysis is implicated in disease such as diabetes, fatty liver disease and cancer ENSG00000166819 ENSG00000125538 ENSG00000173599 ENSG00000123689 ENSG00000026103 PMC8012622__F5 Formation pathway of cytoskeleton structure by F-actin ENSG00000070831 ENSG00000163914 PMC5356911__F1 Extracellular vesicles in mediating progression, metastasis and potential treatment of hepatocellular carcinoma ENSG00000132478 ENSG00000157625 ENSG00000175104 PMC5226619__F3 Inflammasome: an emerging therapeutic oncotarget for cancer prevention ENSG00000115415 ENSG00000168610 PMC8093981__F1 14‐3‐3 proteins in cell signalling pathways and virus infection ENSG00000002330 PMC8093981__F2 14‐3‐3 proteins in cell signalling pathways and virus infection ENSG00000174125 ENSG00000136869 ENSG00000150455 ENSG00000121060 ENSG00000276561 PMC7163447__F9 Proposed model for the role of mitochondrial biogenesis process in developmental fluoride neurotoxicity and protective action of RSV ENSG00000096717 ENSG00000106459 PMC2784025__F8 Proposed model of the underlying mechanism by which NeuroD6 may bridge neuronal differentiation to survival ENSG00000132906 ENSG00000120868 ENSG00000164305 PMC5479446__F1 Schematic view of UPR response in mammals ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC10534925__F3 Epidermal Growth Factor Receptor-Targeted Neoantigen Peptide Vaccination for the Treatment of Non-Small Cell Lung Cancer and Glioblastoma ENSG00000026103 PMC7736222__F2 PGC-to-ProSG-to-SG transition ENSG00000142182 ENSG00000157404 ENSG00000085117 ENSG00000148773 ENSG00000171794 ENSG00000288505 ENSG00000244405 ENSG00000146857 ENSG00000175832 ENSG00000096088 ENSG00000204531 ENSG00000172201 PMC11522757__F1 Regulated cell death (RCD) pathways implicated in pathological cardiac hypertrophy ENSG00000278718 ENSG00000162711 ENSG00000083290 ENSG00000167468 ENSG00000198793 ENSG00000168404 ENSG00000285379 ENSG00000167419 PMC10571577__F3 Acquired mechanisms of resistance to MET-Is ENSG00000157764 ENSG00000138798 ENSG00000146648 PMC10571577__F1 HGF/c-MET signaling pathway ENSG00000019991 ENSG00000164078 ENSG00000198793 ENSG00000026508 ENSG00000185483 ENSG00000168036 ENSG00000168610 ENSG00000146648 PMC9228484__F1 Virus–Host Interplay in Junín Mammarenavirus Infection ENSG00000140287 PMC3857020__F10 Proposed functions of Spry1 and Spry2 in regulation of eyelid closure ENSG00000136158 ENSG00000066468 ENSG00000070193 ENSG00000164056 ENSG00000164690 ENSG00000118971 PMC9228484__F2 Virus–Host Interplay in Junín Mammarenavirus Infection ENSG00000132612 ENSG00000178035 ENSG00000119541 ENSG00000143761 ENSG00000074319 PMC7910064__F5 Schematic figures of metabolic alterations in HCC ENSG00000135218 ENSG00000042832 ENSG00000026103 PMC6498733__F1 Beta-adrenergic signaling pathway in prostatic cancer ENSG00000002330 ENSG00000196591 ENSG00000171791 ENSG00000130669 PMC8190251__F3 Longevity pathways in stress resistance: targeting NAD and sirtuins to treat the pathophysiology of hemorrhagic shock ENSG00000105835 ENSG00000157064 ENSG00000173614 ENSG00000096717 PMC8105194__F1 Endocannabinoid and dopaminergic system: the pas de deux underlying human motivation and behaviors ENSG00000117480 ENSG00000134780 ENSG00000281857 PMC12167312__F1 Developmental neurotoxicity induced by anesthetics targeting GABAARs ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000156273 PMC6997384__F1 Erythropoietin and its derivatives: from tissue protection to immune regulation ENSG00000047410 ENSG00000153208 ENSG00000108691 ENSG00000135218 ENSG00000172216 ENSG00000163739 ENSG00000140545 ENSG00000118520 ENSG00000105639 ENSG00000168610 PMC12167312__F2 Effects of anesthetics targeting GABAARs on different neuronal populations PMC12167312__F3 Neuroprotective mechanisms of NAS ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC5618308__F1A Unlocking the NFKB Conundrum: Embracing Complexity to Achieve Specificity ENSG00000102871 ENSG00000082512 ENSG00000173039 ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000127191 PMC6997384__F2 Erythropoietin and its derivatives: from tissue protection to immune regulation ENSG00000047410 ENSG00000239732 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000168610 ENSG00000184216 PMC6997384__F3 Erythropoietin and its derivatives: from tissue protection to immune regulation ENSG00000100385 ENSG00000134460 ENSG00000047410 ENSG00000134982 ENSG00000127948 PMC2997007__F5 Candidate master switch molecules and signaling pathways involved in LPS-induced inflammatory response of monocyte THP-1 cells ENSG00000259207 ENSG00000099985 ENSG00000164761 ENSG00000173039 ENSG00000120889 ENSG00000168036 ENSG00000007908 ENSG00000171791 ENSG00000164171 ENSG00000049130 ENSG00000115415 ENSG00000170458 ENSG00000125538 ENSG00000173535 ENSG00000185591 ENSG00000162692 ENSG00000115232 PMC2997007__F6 Identification of putative signaling regulators for immune-modification ENSG00000100811 ENSG00000049130 ENSG00000164761 ENSG00000115415 ENSG00000173039 ENSG00000173535 ENSG00000185591 ENSG00000171791 ENSG00000164171 ENSG00000005381 ENSG00000121966 ENSG00000064300 PMC9485555__F8 Exercise inhibits JNK pathway activation and lipotoxicity via macrophage migration inhibitory factor in nonalcoholic fatty liver disease ENSG00000019582 ENSG00000135218 ENSG00000002330 ENSG00000161533 ENSG00000171791 ENSG00000026103 PMC7365992__F3 Extrinsic pathway involves transmembrane receptor mediated interactions ENSG00000168040 ENSG00000026103 PMC7365992__F4 Apoptosis and genes involved in oral cancer - a comprehensive review ENSG00000002330 ENSG00000169857 ENSG00000084774 PMC8493690__F5 Spontaneous recovery from sunitinib-induced disruption of sarcomere in human iPSC-cardiomyocytes and possible involvement of the Hippo pathway ENSG00000150457 ENSG00000131023 PMC11591633__F5 Pharmacological modulation of NCC function in the DCT ENSG00000126562 ENSG00000143867 ENSG00000060237 ENSG00000118515 ENSG00000036828 ENSG00000146021 PMC11591633__F3 Post-translational modifications regulating NCC activity in the DCT ENSG00000126562 ENSG00000143867 ENSG00000060237 ENSG00000135932 ENSG00000146021 PMC11591633__F4 Physiological stimuli that modulate NCC activity ENSG00000126562 ENSG00000143867 ENSG00000060237 ENSG00000118515 ENSG00000146021 PMC11598704__F3 Role of deubiquitinating enzymes on the cell cycle in GC ENSG00000118369 ENSG00000152484 ENSG00000264522 ENSG00000136878 ENSG00000140455 ENSG00000135913 ENSG00000164663 ENSG00000292211 ENSG00000150457 ENSG00000131023 PMC4628672__F3 Pathways analysis of the proteins listed in by means of the Ingenuity software ENSG00000132906 ENSG00000120868 ENSG00000171791 PMC2954727__F1 Working model of the effects of E2 on cell migration ENSG00000291971 ENSG00000156574 ENSG00000160293 ENSG00000146648 PMC6942871__F6 The main targets of miR-221/222 involved in ovarian cancer ENSG00000168374 ENSG00000168610 ENSG00000104081 PMC4454164__F7 Proposed mechanism for RSV in the regulation of mtROS homeostasis through Sirt3 signaling pathway in HUVECs ENSG00000047936 ENSG00000142082 PMC3405730__F2 IL-2 signals by activating three principal signaling pathways, the SHC/RAS/MAP kinase pathway, JAK1/JAK3/STAT5 pathway, and PI 3-K/AKT/p70 S6 kinase pathway ENSG00000100385 ENSG00000134460 ENSG00000105639 PMC4765995__F1 Polyp to colorectal cancer sequences ENSG00000128602 ENSG00000254550 PMC7427429__F3 Pathogen-derived molecules enabling VP22 to evade the DNA-sensing pathway in cells ENSG00000183735 ENSG00000164430 ENSG00000163568 ENSG00000125538 PMC7663815__F11 Crosstalk between androgen and Notch signaling pathways in rodent Sertoli cells ENSG00000148400 ENSG00000145321 ENSG00000114315 PMC8303459__F1 MEK5/ERK5 Pathway in Health and Disease ENSG00000149269 ENSG00000127528 ENSG00000136826 PMC9256747__F2 Molecular mechanisms underlying suicidal NETosis and vital NETosis ENSG00000136869 ENSG00000005381 PMC6520938__F1 Canonical Wnt signaling pathway ENSG00000134982 PMC8116282__F3 Challenges in Paragangliomas and Pheochromocytomas: from Histology to Molecular Immunohistochemistry ENSG00000125166 ENSG00000143252 ENSG00000134086 ENSG00000073578 ENSG00000117118 ENSG00000146701 ENSG00000269858 ENSG00000101365 ENSG00000167985 PMC6520938__F2 Canonical Notch signaling pathway ENSG00000140564 ENSG00000124762 PMC12131388__F6 Drug-pathway-target-disease network of ATBC in ovarian damage (A) and infertility (B) ENSG00000149311 ENSG00000087245 ENSG00000116044 ENSG00000109320 ENSG00000115415 ENSG00000291971 ENSG00000136869 ENSG00000171791 ENSG00000073756 ENSG00000164305 ENSG00000140443 ENSG00000132170 PMC8265496__F4 Necrotizing lymphadenitis may be induced by overexpression of Toll-like receptor7 (TLR7) caused by reduced TLR9 transport in plasmacytoid dendritic cells (PDCs) ENSG00000239732 ENSG00000172936 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC7532258__F8 HLY78 Attenuates Neuronal Apoptosis via the LRP6/GSK3B/Beta-Catenin Signaling Pathway After Subarachnoid Hemorrhage in Rats ENSG00000281324 ENSG00000168036 PMC9216203__F1 Secreted proteins positively related to bone homeostasis and baseline Vo2max ENSG00000105664 ENSG00000112280 ENSG00000183691 ENSG00000083782 ENSG00000095713 ENSG00000198732 PMC7067140__F1 DYSREGULATION OF METABOLIC ENZYMES IN TUMOR AND STROMAL CELLS: ROLE IN ONCOGENESIS AND THERAPEUTIC OPPORTUNITIES ENSG00000131473 ENSG00000136997 ENSG00000169710 ENSG00000115419 ENSG00000062485 ENSG00000119125 PMC11682976__F1 Angiogenesis and EMT regulators in the tumor microenvironment in lung cancer and immunotherapy ENSG00000134086 ENSG00000134853 ENSG00000150630 PMC6169812__F1 New interactors of endothelial adherens junctions (AJs) ENSG00000038382 ENSG00000291971 ENSG00000163914 ENSG00000168036 ENSG00000103769 ENSG00000173706 PMC3938851__F1 Insulin/IGF-1 signaling and regulation ENSG00000177169 ENSG00000106070 ENSG00000169047 PMC4426861__F1 Pathogenesis of Aortopathy in Marfan Syndrome and Related Diseases ENSG00000175104 ENSG00000104368 PMC6338075__F5 Rhythms of life: circadian disruption and brain disorders across the lifespan ENSG00000096717 PMC4739352__F9 Repurposing L-Menthol for Systems Medicine and Cancer Therapeutics? L-Menthol Induces Apoptosis through Caspase 10 and by Suppressing HSP90 ENSG00000002330 ENSG00000110514 ENSG00000137275 ENSG00000102871 ENSG00000120868 PMC2673547__F8 Oncogenic Function of ATDC in Pancreatic Cancer Through Wnt Pathway Activation and Beta-catenin Stabilization ENSG00000134982 ENSG00000168036 PMC12155930__F6 Anti-Inflammatory Activity of Thymol and Thymol-Rich Essential Oils: Mechanisms, Applications, and Recent Findings ENSG00000067900 PMC4850137__F1 Reactions induced by IL-10 ENSG00000100906 ENSG00000198793 ENSG00000173039 ENSG00000213341 ENSG00000182759 PMC8303459__F3 MEK5/ERK5 Pathway in Health and Disease ENSG00000178860 ENSG00000070831 ENSG00000149269 ENSG00000127528 ENSG00000136826 PMC7816678__F3 Diversity in stimulus sensing, fuel sources, and thermogenic mechanisms of brown and beige adipocytes ENSG00000135218 ENSG00000042832 ENSG00000103257 ENSG00000160785 PMC7432891__F1 Schema of the Raf/MEK/extracellular signal-regulated kinase (ERK) pathway and its regulators and effectors ENSG00000142192 ENSG00000177606 ENSG00000185591 ENSG00000171791 PMC5743035__F8 Oxidative Stress in HIV Infection and Alcohol Use: Role of Redox Signals in Modulation of Lipid Rafts and ATP-Binding Cassette Transporters ENSG00000172893 ENSG00000113161 PMC9510596__F1 Tryptophan metabolites in depression: Modulation by gut microbiota PMC5468003__F5 Network analysis obtained from IPA of differentially regulated proteins (p ≤ 0.05) between recurrence (R) and recurrence-free (RF) patients ENSG00000173821 ENSG00000115415 ENSG00000160710 ENSG00000138768 ENSG00000231925 ENSG00000140464 PMC3845579__F1 Regulation of mammalian target of rapamycin (mTOR) by the LKB1/AMPK signaling pathway ENSG00000198793 PMC7833367__F2 Biphasic role of wnt/Beta-catenin pathway in heart muscle development ENSG00000166823 ENSG00000168036 PMC4171766__F2 Top networks observed in Ingenuity Pathway Analysis (IPA) ENSG00000149218 ENSG00000169291 ENSG00000171456 ENSG00000142534 ENSG00000092148 ENSG00000138386 ENSG00000158825 ENSG00000080603 ENSG00000147526 ENSG00000157514 ENSG00000102974 PMC8478550__F3 Gasotransmitters: Potential Therapeutic Molecules of Fibrotic Diseases ENSG00000162711 ENSG00000086991 PMC8478550__F1 Gasotransmitters: Potential Therapeutic Molecules of Fibrotic Diseases ENSG00000162711 ENSG00000105397 ENSG00000131724 ENSG00000105639 PMC8182936__GA Melatonin alleviates titanium nanoparticles induced osteolysis via activation of butyrate/GPR109A signaling pathway ENSG00000162711 ENSG00000125538 PMC8478550__F2 Gasotransmitters: Potential Therapeutic Molecules of Fibrotic Diseases ENSG00000162711 PMC4159950__F2 MicroRNAs As Biomarkers For Clinical Features Of Lung Cancer ENSG00000136997 PMC5833693__F6 Glucocorticoid-induced apoptotic signaling pathway ENSG00000002330 ENSG00000145321 ENSG00000171791 PMC5351412__F1 Differentiation potential of mesenchymal stem cells ENSG00000178860 ENSG00000198793 PMC11225869__F1 In alveolar general capillary endothelial (gCap) cells, IGFBP7 prevents FBXW2-dependent ubiquitination and degradation of NFKB1/2 ENSG00000109320 ENSG00000163453 ENSG00000119402 PMC8583721__F2 Cytoskeleton Reorganization in EndMT—The Role in Cancer and Fibrotic Diseases PMC5702042__F8 Suggested model of activation of the NLRP3 inflammasome by Fonsecaea pedrosoi hyphae in macrophages ENSG00000162711 ENSG00000150782 ENSG00000125538 PMC3867791__F6 Regulated in DNA Damage and Development 1 (REDD1) promotes cell survival during serum deprivation by sustaining repression of signaling through the mechanistic target of rapamycin in complex 1 (mTORC1) ENSG00000177169 ENSG00000128272 ENSG00000144895 PMC3823475__F2 Membrane VEGF receptors expressed by astroglial tumour cells ENSG00000128052 ENSG00000145321 PMC3828821__F1 How does the metabolism of tumour cells differ from that of normal cells ENSG00000135423 ENSG00000172005 ENSG00000169710 ENSG00000074410 ENSG00000159399 PMC9367238__F2 Mechanistic and functional extrapolation of SET and MYND domain-containing protein 2 to pancreatic cancer ENSG00000143499 ENSG00000139687 ENSG00000114738 ENSG00000198625 PMC4294653__F12 mTOR signaling pathway regulated by PLB in PC-3 cells.Notes: PC-3 cells were treated with 5 μM PLB for 24 hours and the protein samples were subject to quantitative proteomic analysis ENSG00000177169 ENSG00000163435 ENSG00000171105 ENSG00000163914 ENSG00000169047 ENSG00000173599 ENSG00000164327 ENSG00000132341 PMC6289345__F5 The proposed metabolic pathway of cryptotanshinone in HLMs ENSG00000171234 ENSG00000165841 ENSG00000140505 ENSG00000156096 ENSG00000255974 PMC5058685__F7 Hypermethylated in cancer 1(HIC1) suppresses non-small cell lung cancer progression by targeting interleukin-6/Stat3 pathway ENSG00000087245 ENSG00000168610 PMC4294653__F13 mTOR signaling pathway regulated by PLB in DU145 cells.Notes: DU145 cells were treated with 5 μM PLB for 24 hours and the protein samples were subject to quantitative proteomic analysis ENSG00000177169 ENSG00000163435 ENSG00000171105 ENSG00000169047 ENSG00000164327 PMC4036317__F11 How PLCG1 regulates USP1 phosphorylation to mediate 20E-induced gene expression for metamorphosis ENSG00000162607 ENSG00000124181 PMC9600272__F2 Emerging Role of ERBB2 in Targeted Therapy for Metastatic Colorectal Cancer: Signaling Pathways to Therapeutic Strategies ENSG00000183735 ENSG00000138798 ENSG00000198793 ENSG00000136997 ENSG00000112715 ENSG00000100485 PMC4294653__F11 PLB regulates apoptosis signaling pathway in PC-3 cells.Notes: PC-3 cells were treated with 5 μM PLB for 24 hours and the protein samples were subject to quantitative proteomic analysis ENSG00000002330 ENSG00000120868 ENSG00000171791 ENSG00000115760 ENSG00000084774 ENSG00000115317 ENSG00000026103 PMC3392173__F1 Wnt signaling pathways ENSG00000138795 ENSG00000156076 ENSG00000291971 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC4337883__F2 Choline metabolism in malignant transformation ENSG00000185591 ENSG00000111666 PMC4394890__F2 MiRNA and TF co-regulatory network analysis for the pathology and recurrence of myocardial infarction ENSG00000100811 ENSG00000175206 ENSG00000143390 ENSG00000178951 ENSG00000173039 ENSG00000171791 ENSG00000112715 ENSG00000168610 ENSG00000196628 ENSG00000245848 ENSG00000172216 ENSG00000100387 ENSG00000177606 ENSG00000136997 ENSG00000185591 ENSG00000128342 ENSG00000167637 ENSG00000102974 PMC4394890__F5 MiRNA and TF co-regulatory network analysis for the pathology and recurrence of myocardial infarction ENSG00000100811 ENSG00000177606 ENSG00000136997 ENSG00000185591 ENSG00000166278 ENSG00000171791 ENSG00000112715 ENSG00000108821 ENSG00000179348 PMC11098157__F1 Metabolic pathway for S‐warfarin PMC10568316__F2 Mφ-related inflammatory signaling pathways in NEC ENSG00000278718 ENSG00000162711 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC8568295__F9 Hub gene multi-factor regulatory network ENSG00000169896 ENSG00000159216 ENSG00000066336 ENSG00000185591 ENSG00000167182 ENSG00000136826 PMC7242393__F10 Mitochondrial phosphatase PGAM5 modulates cellular senescence by regulating mitochondrial dynamics ENSG00000198793 ENSG00000247077 PMC10568316__F1 Multifunctional role and mechanism of IMφs in NEC pathogenesis ENSG00000118520 PMC3651771__F1 Synstatin: a selective inhibitor of the syndecan-1-coupled IGF1RAvB3 integrin complex in tumorigenesis and angiogenesis ENSG00000115884 ENSG00000140443 PMC4326712__F2 Simplified synopsis on the PI3K-AKT and RAS-MAPK signaling pathways and their interactions ENSG00000033327 ENSG00000198793 PMC7010853__F8 Speculatively schematic diagram of this scientific hypothesis including the most significant SF (CLEF5), OS-SEs (GSG1L|35698|AP, GSG1L|35696|AP) and downstream pathway (Primary bile acid synthesis) ENSG00000161082 PMC8766727__F6 USP14: Structure, Function, and Target Inhibition ENSG00000148400 ENSG00000168036 ENSG00000101557 PMC7685564__F1 Cross-Kingdom Activation of Vibrio Toxins by ADP-Ribosylation Factor Family GTPases ENSG00000108582 ENSG00000143761 ENSG00000001626 ENSG00000165527 PMC8185986__F2 F ig . 2.Mϕ regulation of PMN chemotaxis ENSG00000136869 PMC3904428__F1 Ral GTPase pathway in metastatic bladder cancer: key mediator and therapeutic target ENSG00000017797 ENSG00000006451 PMC7967180__F1 The leukotriene signaling pathway ENSG00000226275 PMC8349014__F1 Flavonoids on diabetic nephropathy: advances and therapeutic opportunities ENSG00000198793 PMC10968226__F2 TRPV4 channels in osteoarthritis ENSG00000125398 ENSG00000157766 PMC7582185__F4 Transcription factor CREB1 exhibits an opposite regulation in the downstream genes between WT and VCP TG mice in response to 2W TAC ENSG00000160888 ENSG00000091664 ENSG00000145687 ENSG00000175868 ENSG00000042832 ENSG00000206579 ENSG00000053438 ENSG00000167470 ENSG00000112379 ENSG00000240891 ENSG00000122877 ENSG00000143839 ENSG00000050030 ENSG00000141744 ENSG00000165280 ENSG00000187123 ENSG00000183662 ENSG00000049768 ENSG00000136826 ENSG00000123999 ENSG00000171502 ENSG00000148773 ENSG00000136997 ENSG00000125538 ENSG00000277263 ENSG00000293532 ENSG00000180787 ENSG00000221869 ENSG00000164120 ENSG00000102172 ENSG00000169836 ENSG00000224320 ENSG00000069482 ENSG00000177606 ENSG00000198576 ENSG00000115155 ENSG00000180332 ENSG00000164949 PMC6529853__F5 Dysfunctional subpathway (path:04020_1) of calcium signaling pathway in CESC ENSG00000156049 ENSG00000122420 ENSG00000136160 ENSG00000151617 ENSG00000075073 PMC9368906__F4 LncRNA H19 Impairs Chemo and Radiotherapy in Tumorigenesis ENSG00000026508 ENSG00000168036 PMC7711540__F5 Validation and pathway analysis of elevated S100A8 protein in FSHD ENSG00000182628 ENSG00000143546 ENSG00000163220 ENSG00000106771 ENSG00000115718 ENSG00000108518 ENSG00000086758 ENSG00000101974 ENSG00000177606 ENSG00000120137 ENSG00000034510 ENSG00000136869 ENSG00000186832 PMC7830067__F1 Metformin enhances CD8+/CD4+ ratio to favor an immunoreactive microenvironment ENSG00000111537 ENSG00000198793 ENSG00000049768 PMC11831438__F10 Scheme depicting the proposed mechanisms for the neuroprotective effects of Tat‐Nrf2 peptide treatment in ischemic stroke ENSG00000112701 PMC7416697__F7 ABCC4 function in SHH signaling ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC3571350__F10 Schematic model of IFN-induced apoptosis in WISH cells ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000168040 ENSG00000064012 ENSG00000164305 PMC11014460__F1 Responses of HIFs to hypoxia or hyperoxia ENSG00000134086 PMC5081117__F6 Targeted transcriptomic analysis ENSG00000125166 ENSG00000262635 ENSG00000162882 ENSG00000145293 ENSG00000116984 ENSG00000149089 ENSG00000137992 ENSG00000059573 ENSG00000099810 ENSG00000123505 ENSG00000002549 ENSG00000116771 ENSG00000113790 ENSG00000105552 ENSG00000117305 ENSG00000084774 PMC9247101__F5 Targeting fibrosis: mechanisms and clinical trials ENSG00000138798 PMC7202451__F5 Gene expression in the actin cytoskeleton signaling pathway for the hepatic transcriptome of S ENSG00000172380 ENSG00000291971 ENSG00000134982 ENSG00000102302 ENSG00000089159 PMC4462367__F2 Schematic diagram of the signaling of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway involved in human cancers ENSG00000109452 ENSG00000002330 ENSG00000164327 ENSG00000146648 PMC7202451__F6 Gene expression of the ILK Signaling pathway in the hepatic transcriptome of S ENSG00000196531 ENSG00000111057 ENSG00000198793 ENSG00000163914 ENSG00000136997 ENSG00000164327 ENSG00000071051 ENSG00000100985 ENSG00000148484 ENSG00000164305 ENSG00000089159 PMC10419859__F2 ATX/LPA signaling pathway in different inflammatory diseases ENSG00000163914 ENSG00000198670 PMC7202451__F7 Gene expression of the signaling by rho family GTPases pathway in the hepatic transcriptome of S ENSG00000095321 ENSG00000131095 ENSG00000123143 ENSG00000288461 ENSG00000227345 PMC4462367__F1 Schematic diagram of estrogen receptor (ER) signaling ENSG00000198793 ENSG00000185591 PMC3097472__F1 Methionine, an essential amino acid required for protein synthesis, is the source of methyl groups for a number of methylation reactions such as methylation of nucleic acids, proteins, biogenic amines, phospholipids, and for creatine synthesis etc PMC7549162__F6 Comprehensive network construction of crucial signaling pathways and DEGs associated with HBV-ALF ENSG00000011600 ENSG00000224320 ENSG00000122223 ENSG00000163131 ENSG00000115904 ENSG00000277263 ENSG00000180644 ENSG00000158869 ENSG00000126264 PMC2882734__F6 Pathways of VLC-PUFA biosynthesis ENSG00000118402 ENSG00000119915 ENSG00000066322 ENSG00000197977 PMC9054177__F1 Molecular Basis of the Effect of Atorvastatin Pre-treatment on Stem Cell Therapy in Chronic Ischemic Diseases – Critical Limb Ischemia ENSG00000134086 ENSG00000002330 ENSG00000198793 ENSG00000163914 PMC11969464__F2 Ingenuity pathway analysis of differentially enriched proteins ENSG00000002330 ENSG00000157764 ENSG00000130396 ENSG00000198561 ENSG00000198793 ENSG00000189056 ENSG00000122194 ENSG00000132639 ENSG00000187672 ENSG00000163539 ENSG00000107263 ENSG00000197283 ENSG00000220205 ENSG00000137076 ENSG00000152767 ENSG00000132535 PMC10144233__F1 Heme b biosynthesis pathway ENSG00000122966 ENSG00000126088 ENSG00000172005 ENSG00000256269 ENSG00000188690 PMC11969464__F3 Visualization analysis of pathways identified from normalized, significantly differentially-SUMO-enriched proteins ENSG00000152932 ENSG00000077522 ENSG00000115310 ENSG00000187672 ENSG00000132676 ENSG00000107581 ENSG00000179295 ENSG00000160469 ENSG00000171992 ENSG00000164061 ENSG00000116106 ENSG00000078053 ENSG00000143761 ENSG00000168924 ENSG00000047849 ENSG00000105723 ENSG00000011347 PMC4890990__F1 Molecular mechanisms of long noncoding RNAs on gastric cancer ENSG00000223573 ENSG00000159216 ENSG00000112242 ENSG00000198793 ENSG00000127528 ENSG00000185591 ENSG00000105810 ENSG00000171791 PMC10144233__F2 Formation of uroporphyrinogen III (UPG III) and the branching of the heme b biosynthesis ENSG00000108582 ENSG00000105251 ENSG00000126088 ENSG00000256269 ENSG00000188690 PMC11514755__F8 NF-kappaB signalling pathway ENSG00000170458 ENSG00000056558 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000162692 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC7016717__F3 Oncogenic activation of the STAT3 pathway in T-cell lymphoma ENSG00000105639 ENSG00000168610 PMC7016717__F2 Janus kinase 1 (JAK1)/STAT3 signaling in DLBCL ENSG00000100906 ENSG00000171791 ENSG00000168610 ENSG00000077150 ENSG00000144802 ENSG00000140379 ENSG00000156127 ENSG00000177606 ENSG00000136997 ENSG00000137265 ENSG00000118515 ENSG00000213999 ENSG00000172936 PMC9240244__F7 Working model of the protective effects of Rb1 against D-GalN/LPS induced ALI: Rb1 inhibition of the TLR4/MyD88/NFKB signaling pathway and NLRP3 inflammasome activation ENSG00000162711 ENSG00000172936 ENSG00000139687 PMC9570477__F7 An Integrative Transcriptional Network Revealed Spatial Molecular Interplay Underlying Alantolactone and Inulin Biosynthesis in Inula racemosa Hook f. ENSG00000157005 PMC2908475__F2 The intracellular signaling network regulating T-cell trafficking and differentiation ENSG00000188404 ENSG00000164136 ENSG00000126353 ENSG00000103522 PMC6719725__F6 Assessment of network module identification across complex diseases ENSG00000178078 ENSG00000155926 ENSG00000163599 ENSG00000173039 ENSG00000160181 ENSG00000164327 ENSG00000162924 ENSG00000154016 ENSG00000115317 ENSG00000169495 ENSG00000112116 ENSG00000138378 ENSG00000213658 ENSG00000160180 ENSG00000005381 ENSG00000127948 ENSG00000163515 PMC5824497__F2 NAD+-Dependent Family of Sirtuins in Cerebral Ischemia and Preconditioning ENSG00000187531 ENSG00000105835 ENSG00000123572 ENSG00000278488 ENSG00000157064 ENSG00000124523 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000089163 ENSG00000283100 PMC6003041__F3 Regulation of SREBP1 and lipid metabolism by oncogenic signaling in CSCs ENSG00000156885 ENSG00000122971 ENSG00000127884 PMC6003041__F4 Interaction between oncogenic signaling and lipid desaturation in CSCs ENSG00000131473 ENSG00000138798 ENSG00000169710 ENSG00000146648 PMC6838739__F1 Signaling pathways in osteoclast (OC) differentiation, survival and death ENSG00000152266 ENSG00000102871 ENSG00000198793 ENSG00000177606 ENSG00000168040 ENSG00000175104 PMC8151162__F4 Transcriptome Analysis of the Japanese Pine Sawyer Beetle, Monochamus alternatus, Infected with the Entomopathogenic Fungus Metarhizium anisopliae JEF-197 ENSG00000183735 ENSG00000172936 ENSG00000189430 ENSG00000064012 ENSG00000096264 PMC10933439__F1 Canonical Activin-, BMP-, and IFN-mediated signaling pathways ENSG00000184979 ENSG00000121989 ENSG00000170365 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000198742 ENSG00000120693 ENSG00000204217 ENSG00000114739 PMC5705900__F8 Possible mechanisms through which crocetin and AS101 reverse the early adaptive response of the ovary to CPM ENSG00000135678 ENSG00000142082 PMC8674449__F2 Ecogenomics Reveals Microbial Metabolic Networks in a Psychrophilic Methanogenic Bioreactor Treating Soy Sauce Production Wastewater ENSG00000172005 ENSG00000188158 PMC5455971__F2 Targeting iron metabolism in drug discovery and delivery ENSG00000170365 ENSG00000010704 ENSG00000106327 ENSG00000178752 ENSG00000105697 ENSG00000168610 PMC3706566__F6 Hibernating squirrel muscle activates the endurance exercise pathway despite prolonged immobilization ENSG00000116688 ENSG00000175567 ENSG00000096717 ENSG00000142082 ENSG00000171109 ENSG00000106459 ENSG00000214253 PMC2851161__F1 The Notch signaling pathway ENSG00000148400 ENSG00000074181 PMC7926651__F4 Main mechanisms of Kupffer cell activation during chronic ethanol exposure ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC8593816__F5 Clinical Significance of Screening Differential Metabolites in Ovarian Cancer Tissue and Ascites by LC/MS ENSG00000188641 ENSG00000133313 ENSG00000111012 ENSG00000151726 ENSG00000117054 ENSG00000150656 ENSG00000134824 ENSG00000167910 ENSG00000169710 ENSG00000147647 ENSG00000275565 ENSG00000186104 PMC2492871__F4 Networks top-ranked by Ingenuity Pathway analysis after knockdown of TP53 (A) and LSR1+TP53 (B) ENSG00000048392 ENSG00000185215 ENSG00000164266 ENSG00000196154 PMC5833825__F6 Photosensitization of A2E triggers telomere dysfunction and accelerates retinal pigment epithelium senescence ENSG00000197713 ENSG00000125538 ENSG00000121966 PMC11931864__F6 Molecular mechanisms through which hUC-MSC-sec improves aged oocyte quality ENSG00000178860 ENSG00000137707 PMC7096478__F7 The possible mechanisms used by M ENSG00000148400 ENSG00000134982 ENSG00000114315 PMC5292006__F4 Ingenuity pathway analysis of uniquely hypomethylated promoters ENSG00000120833 ENSG00000213658 ENSG00000292373 ENSG00000010810 ENSG00000163599 ENSG00000105639 PMC7096478__F8 The possible mechanisms used by M ENSG00000159216 ENSG00000039987 PMC2586079__F1 COMPLEMENT ACTIVATION FRAGMENT Bb IN EARLY PREGNANCY AND SPONTANEOUS PRETERM BIRTH ENSG00000288512 ENSG00000166278 ENSG00000182326 PMC7096478__F9 The possible mechanisms used by M ENSG00000159216 ENSG00000148400 PMC7214175__F7 Proposed model of metformin‐induced activation of the Hippo pathway in drug‐sensitive and drug‐resistant breast cancer cells ENSG00000186575 ENSG00000139926 PMC7303083__F7 LPS-TLR4 MAPK pathway stimulated by 1% ECVE treatment of LPS-matured MoDCs ENSG00000134070 ENSG00000189403 ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000184216 PMC4836665__F3 Differences in Whole Blood Gene Expression Associated with Infection Time-Course and Extent of Fetal Mortality in a Reproductive Model of Type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Infection ENSG00000105325 ENSG00000065613 ENSG00000107338 ENSG00000108055 ENSG00000134982 ENSG00000010810 ENSG00000164754 ENSG00000113263 ENSG00000117399 PMC4123209__F2 Tale of two cytokines: IL-17 and IL-22 in asthma and infection ENSG00000105397 ENSG00000082512 ENSG00000175104 ENSG00000127191 ENSG00000168610 ENSG00000163702 PMC6720052__F7 Schematic of the signalling pathways involved in AVE 0991-attenuated pyroptosis and hepatocyte damage induced by heat stress by inhibiting the ROS-NLRP3 inflammatory signalling pathway ENSG00000162711 ENSG00000086991 PMC8634426__F1 From DNA Damage to Cancer Progression: Potential Effects of Cytolethal Distending Toxin ENSG00000188486 ENSG00000149311 PMC11907527__F6 Subgroup-specific heterogeneity in common pathways ENSG00000019991 ENSG00000291603 ENSG00000048462 ENSG00000138798 ENSG00000095015 ENSG00000196591 ENSG00000203710 ENSG00000111321 ENSG00000150455 ENSG00000135341 ENSG00000150782 ENSG00000277571 ENSG00000077150 ENSG00000130164 ENSG00000244405 ENSG00000082512 ENSG00000196352 ENSG00000197943 ENSG00000157625 ENSG00000275565 ENSG00000064012 ENSG00000115594 ENSG00000100065 ENSG00000198286 ENSG00000148346 ENSG00000166167 ENSG00000104365 ENSG00000099985 ENSG00000109321 ENSG00000173039 ENSG00000027697 ENSG00000277804 ENSG00000157017 ENSG00000213341 ENSG00000127191 ENSG00000285281 ENSG00000285456 ENSG00000226275 ENSG00000244687 ENSG00000118503 ENSG00000163235 ENSG00000102245 ENSG00000172936 ENSG00000131323 ENSG00000100985 ENSG00000175104 ENSG00000184216 ENSG00000136689 PMC8256170__F2 OX40/OX40L Axis Regulates T Follicular Helper Cell Differentiation: Implications for Autoimmune Diseases ENSG00000134982 ENSG00000127191 PMC4266467__F1 iNOS: A Potential Therapeutic Target for Malignant Glioma ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC8637192__F6 Copper Tolerance Mechanism of the Novel Marine Multi-Stress Tolerant Yeast Meyerozyma guilliermondii GXDK6 as Revealed by Integrated Omics Analysis ENSG00000122966 PMC4532730__F1 Intercellular apoptosis-inducing ROS signaling ENSG00000167419 PMC11907527__F3 Additional analysis on Amini et al, J Neuroinflammation, 2023 (PMID: 36691064) ENSG00000110944 ENSG00000019991 ENSG00000136141 ENSG00000065675 ENSG00000101000 ENSG00000108389 ENSG00000163599 ENSG00000198793 ENSG00000172572 ENSG00000108654 ENSG00000114948 ENSG00000116251 ENSG00000129351 ENSG00000151692 ENSG00000179295 ENSG00000144161 ENSG00000112685 ENSG00000153283 ENSG00000100714 ENSG00000144426 ENSG00000168234 ENSG00000082512 ENSG00000144840 ENSG00000134245 ENSG00000105810 ENSG00000133134 ENSG00000115419 ENSG00000163644 ENSG00000027075 ENSG00000147044 ENSG00000151882 ENSG00000088179 ENSG00000197635 ENSG00000120915 ENSG00000018510 ENSG00000137070 ENSG00000133789 ENSG00000155561 ENSG00000120910 ENSG00000117020 ENSG00000172840 ENSG00000078589 ENSG00000131018 ENSG00000107485 ENSG00000170989 ENSG00000125245 ENSG00000152465 ENSG00000183495 PMC8689983__F3 Reactome pathway knowledgebase 2022 ENSG00000066044 ENSG00000034713 ENSG00000064393 PMC2492871__F5 Networks top-ranked by Ingenuity Pathway analysis after knockdown of LSR1 (A-B) ENSG00000163435 ENSG00000011422 ENSG00000141052 ENSG00000135919 PMC2492871__F6 Networks top-ranked by Ingenuity Pathway analysis after knockdown of LSR2 (A-B) ENSG00000164266 ENSG00000135919 PMC6545975__F1 Receptor signaling pathway and recruitment of IL-1RAcP ENSG00000136696 ENSG00000136694 ENSG00000172936 PMC8300159__F1 Crossroads between Zinc and Steroidal Implant-Induced Growth of Beef Cattle ENSG00000087245 ENSG00000113070 ENSG00000100985 ENSG00000146648 ENSG00000140443 PMC6506518__F8 Proposed multi-target and multi-component action modes of hawk tea as a previously unrecognized cholesterol-lowering agent ENSG00000130164 ENSG00000015520 PMC11929655__F3 Protein–Protein Interaction (PPI) Network and Enrichment Analysis ENSG00000170027 ENSG00000175793 ENSG00000265972 PMC4761371__F2 RhoGTPase switch at the cell–cell contact ENSG00000038382 ENSG00000156299 ENSG00000170558 ENSG00000160293 PMC4532730__F8 High concentrations of photofrin-derived singlet oxygen triggers the generation of cell-derived singlet oxygen, catalase inactivation and intercellular ROS-dependent apoptosis signaling through the NO/peroxynitrite and HOCl signaling pathway ENSG00000167419 PMC4532730__F9 Catalase inactivation by low concentrations of photofrin-derived singlet oxygen requires an additional amplification step that is mediated by the FAS receptor and caspase-8A ENSG00000167419 PMC9008482__F2 mRNA Translation Is Dynamically Regulated to Instruct Stem Cell Fate ENSG00000155506 ENSG00000163435 ENSG00000144895 ENSG00000198793 PMC11929655__F1 MTOR signaling pathway ENSG00000168209 ENSG00000198793 PMC6895189__F4 Adaptive divergence of Notch signalling pathway in tiger ENSG00000004975 ENSG00000005339 ENSG00000196782 ENSG00000100060 ENSG00000184916 ENSG00000175029 ENSG00000090932 ENSG00000110042 ENSG00000106003 ENSG00000091073 ENSG00000143801 ENSG00000205155 ENSG00000196498 ENSG00000133961 ENSG00000161202 ENSG00000114315 ENSG00000100603 PMC7102443__F8 Pleiotropic functions of Htt in the TLR-4 signal transduction system in BMMCs ENSG00000010810 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC7048264__F7 HIF-2A regulation via DDX28 ENSG00000173933 ENSG00000182810 PMC11842281__F4 PI3K‐AKT signaling pathway by nSolver Software (PathView) ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000169047 PMC8722197__F6 Endophytic fungus Pseudodidymocyrtis lobariellae KL27 promotes taxol biosynthesis and accumulation in Taxus chinensis ENSG00000105722 PMC5923370__F3 Summary of discussed cancer-relevant pathways that activate YAP and TAZ ENSG00000167601 ENSG00000163235 ENSG00000291971 ENSG00000138798 ENSG00000163914 ENSG00000168036 ENSG00000146648 PMC4926186__F2 Alphavirus Infection: Host Cell Shut-Off and Inhibition of Antiviral Responses ENSG00000163435 ENSG00000105397 ENSG00000144895 ENSG00000115415 ENSG00000142166 PMC6860913__F3 TLR9 has been proposed to signal through two independent cascades, (A) the canonical inflammatory pathway and (B) the non-canonical stress tolerance pathway ENSG00000239732 ENSG00000172936 ENSG00000175104 ENSG00000276561 PMC12170596__F3 Microbiota dysbiosis alters gastric epithelial cell signaling pathways ENSG00000165556 ENSG00000164430 ENSG00000102837 ENSG00000168036 ENSG00000185591 ENSG00000175792 PMC12170596__F4 Microbiota shapes the suppressive immune microenvironment ENSG00000162711 ENSG00000239732 ENSG00000145321 ENSG00000136869 ENSG00000168610 PMC5147901__F3 Modeling the Role of Lanthionine Synthetase C-Like 2 (LANCL2) in the Modulation of Immune Responses to Helicobacter pylori Infection ENSG00000182578 ENSG00000100225 ENSG00000168329 ENSG00000111537 ENSG00000118242 ENSG00000196498 ENSG00000127191 ENSG00000136826 PMC7586489__F1 Locations of DNA base lesions govern TNR instability through BER PMC7586489__F2 TNR expansions and deletions through BER ENSG00000132646 PMC12170596__F2 Microbiota increases host cell genomic damage and suppresses genome repair ENSG00000113318 ENSG00000172936 ENSG00000136869 ENSG00000095002 PMC3552307__F1 Double-stranded and single-stranded RNA signaling pathway ENSG00000239732 ENSG00000172936 ENSG00000131323 ENSG00000168040 ENSG00000175104 ENSG00000127191 ENSG00000276561 ENSG00000164342 PMC3349304__F6 Identification of transcripts and proteins associated with hemocytes ENSG00000172936 ENSG00000135404 ENSG00000162924 ENSG00000175104 ENSG00000076604 PMC6600448__F2 Molecular mechanisms of alcohol-induced apoptosis and autophagy in hepatocytes ENSG00000130649 ENSG00000168036 ENSG00000168040 ENSG00000168610 ENSG00000010671 ENSG00000026103 PMC11674514__F3 Various IL6 pathway inhibitions PMC8033034__F1 Unfolded protein response (UPR) signaling pathway ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8033034__F2 Relevant events involving IRE1A and PERK proteins at mitochondria–ER contacts (MERCs) ENSG00000128272 ENSG00000116688 ENSG00000198793 PMC11839352__F4 枸杞多糖改善高原低氧环境雌性大鼠生殖损伤的机制研究 ENSG00000117298 ENSG00000113161 ENSG00000106688 ENSG00000112715 ENSG00000196396 ENSG00000164305 ENSG00000274542 ENSG00000149295 ENSG00000112038 ENSG00000086205 ENSG00000162139 ENSG00000239732 ENSG00000171720 ENSG00000128052 ENSG00000136869 ENSG00000082556 ENSG00000027075 ENSG00000087245 ENSG00000163399 ENSG00000150594 ENSG00000197081 ENSG00000196839 ENSG00000173083 ENSG00000085662 ENSG00000168610 ENSG00000126012 ENSG00000127445 ENSG00000197901 ENSG00000073734 ENSG00000196689 ENSG00000146648 ENSG00000159399 ENSG00000176387 ENSG00000262243 PMC5562963__F1 Early and lethal neurodegeneration with myasthenic and myopathic features ENSG00000101901 ENSG00000000419 ENSG00000173540 ENSG00000139133 ENSG00000033011 ENSG00000172269 ENSG00000163933 ENSG00000088035 ENSG00000120697 ENSG00000129255 ENSG00000136908 ENSG00000167130 PMC11674514__F1 IL6 classical and trans-signaling activation pathways ENSG00000137845 PMC5779028__F8 Local TRPV4 channel‐dependent Ca2+signaling regulates endothelium‐dependent vasodilation in resistance‐sized PAs ENSG00000144063 ENSG00000145321 PMC8946148__F2 Emerging Roles for Mammalian Target of Rapamycin (mTOR) Complexes in Bladder Cancer Progression and Therapy ENSG00000155792 ENSG00000164327 ENSG00000167965 ENSG00000146648 PMC7794044__F4 Signalling pathways activated by peptidoglycan upon stimulation of NOD-like receptors ENSG00000162711 ENSG00000167207 ENSG00000187796 ENSG00000125538 ENSG00000091592 ENSG00000142405 ENSG00000175104 ENSG00000276561 PMC8206194__F2 Osteoporosis: Current and Emerging Therapies Targeted to Immunological Checkpoints ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC5993794__F3 Ingenuity Pathway Analysis of SNX8, PCP2, KNG1, and RORA ENSG00000130340 ENSG00000173548 ENSG00000106266 ENSG00000069667 PMC4383744__F1 Complement in paroxysmal nocturnal hemoglobinuria: exploiting our current knowledge to improve the treatment landscape ENSG00000196352 PMC4383744__F2 Complement in paroxysmal nocturnal hemoglobinuria: exploiting our current knowledge to improve the treatment landscape ENSG00000113600 ENSG00000203710 ENSG00000166278 ENSG00000117322 ENSG00000182326 PMC8704836__F6 Lowering pO2 Interacts with Photoperiod to Alter Physiological Performance of the Coastal Diatom Thalassiosira pseudonana ENSG00000006695 ENSG00000117118 PMC11667232__F6 Big data analytics for aortic aneurysm ENSG00000100234 ENSG00000262406 ENSG00000157933 ENSG00000197471 ENSG00000106603 ENSG00000127948 PMC9348623__F6 Molecular Mechanisms of the Convergent Adaptation of Bathypelagic and Abyssopelagic Fishes ENSG00000291971 ENSG00000163914 ENSG00000288263 PMC8623813__F1 Clinical Translation of Combined MAPK and Autophagy Inhibition in RAS Mutant Cancer ENSG00000177606 ENSG00000136997 PMC7855863__F3 Key Metabolic Functions of Beta-Arrestins: Studies with Novel Mouse Models ENSG00000169047 PMC3782237__F4 Mammalian target of rapamycin pathway is deregulated by mutations in cancer ENSG00000138798 ENSG00000198793 PMC3204462__F1 TRAIL signaling pathway and regulatory proteins ENSG00000132906 ENSG00000002330 ENSG00000186635 ENSG00000278268 ENSG00000198576 ENSG00000168040 ENSG00000127191 ENSG00000132676 PMC7149927__F9 Schematic diagram showing the effect of MG-infection on chicken thymus tissues ENSG00000162711 ENSG00000125538 ENSG00000198793 ENSG00000172936 ENSG00000175104 PMC6736567__F1 Canonical Hh signaling ENSG00000078747 ENSG00000173599 ENSG00000128602 ENSG00000118971 PMC12057268__F1 Interactions between chronic inflammatory pathways, MetS, and various skin diseases ENSG00000134460 ENSG00000138798 ENSG00000164399 ENSG00000113520 ENSG00000136869 ENSG00000112182 ENSG00000162692 ENSG00000146648 PMC11624276__F8 Schematic diagram displaying the role and mechanism of GPR160 in bone cancer pain ENSG00000196549 ENSG00000185591 ENSG00000173890 PMC5141645__F1 Schematic diagram of HGF/c-MET signal transduction pathway ENSG00000019991 ENSG00000198793 ENSG00000168610 PMC5125891__F3 Sphingolipids in Mitochondria ENSG00000102871 ENSG00000168040 ENSG00000026103 PMC7012211__F6 Schematic diagram displaying the impact of AREG on intrinsic apoptosis signaling ENSG00000002330 ENSG00000109321 ENSG00000146648 PMC5584463__F1 Mechanistic target of rapamycin (mTOR): A mediator of social development ENSG00000198793 PMC7586489__F4 Crosstalk between BER and MMR promotes TNR expansions and suppresses TNR deletions PMC2721971__F3 EGFR-GEP100-Arf6-AMAP1 Signaling Pathway Specific to Breast Cancer Invasion and Metastasis† ENSG00000110395 ENSG00000138798 ENSG00000165527 ENSG00000146648 PMC8348732__F4 Post-Translational Acetylation and Deacetylation of Signaling Proteins and Transcription Factors after Cerebral Ischemia: Facts and Hypotheses ENSG00000094631 ENSG00000171720 ENSG00000096717 ENSG00000283100 PMC9386470__F1 BTK, the new kid on the (oncology) block? ENSG00000177455 ENSG00000186716 ENSG00000136997 ENSG00000172936 ENSG00000010671 PMC9061815__F5 scATAC-seq analysis and heterogeneity of regulation between MGE and LGE ENSG00000147862 ENSG00000165804 ENSG00000130522 ENSG00000196628 ENSG00000136231 ENSG00000106852 ENSG00000162624 ENSG00000178573 ENSG00000113532 ENSG00000291761 ENSG00000132677 ENSG00000174963 ENSG00000184486 ENSG00000182463 ENSG00000172201 ENSG00000152558 ENSG00000198914 ENSG00000164684 ENSG00000165655 ENSG00000091656 ENSG00000108055 ENSG00000143878 ENSG00000176887 ENSG00000124766 ENSG00000021645 ENSG00000136352 ENSG00000157005 ENSG00000081189 ENSG00000291420 ENSG00000004848 ENSG00000139352 ENSG00000016082 ENSG00000106459 ENSG00000175745 ENSG00000146592 ENSG00000177606 ENSG00000034510 ENSG00000205927 ENSG00000273529 PMC11939868__F2 Long non-coding RNAs (lncRNAs) regulate immune escape in the tumor immune microenvironment (TME) ENSG00000168610 PMC11939868__F3 LncRNA and Tils in TNBC ENSG00000231179 ENSG00000204520 PMC7898723__F3 Whole‐exome sequencing of non‐BRCA1/BRCA2 mutation carrier cases at high‐risk for hereditary breast/ovarian cancer ENSG00000149311 ENSG00000171320 ENSG00000132781 ENSG00000187741 ENSG00000139372 ENSG00000112039 ENSG00000140398 ENSG00000035928 ENSG00000276787 ENSG00000095002 ENSG00000183765 PMC2826517__F1 The current understanding of PELP1 signaling pathway ENSG00000291971 ENSG00000138798 ENSG00000168610 ENSG00000146648 ENSG00000141456 PMC6387057__F1 Schematic depiction of the mTOR signaling network ENSG00000157933 ENSG00000198793 ENSG00000155792 ENSG00000112561 ENSG00000084774 PMC5860940__F2 Simplified overview of the intracellular signaling mechanisms governing CCA cell motility and invasiveness ENSG00000168283 ENSG00000125398 ENSG00000198793 ENSG00000101115 ENSG00000196154 ENSG00000109670 PMC8615881__F1 Matrix Metalloproteinases in Endometriosis: A Potential Target ENSG00000125571 ENSG00000087245 ENSG00000157368 ENSG00000137673 ENSG00000149968 ENSG00000166670 ENSG00000100985 ENSG00000105639 ENSG00000168610 ENSG00000146648 ENSG00000171560 PMC8279385__F2 Specialized pro-resolving lipid mediators in pulmonary inflammation diseases: mechanisms and development ENSG00000137033 ENSG00000166090 PMC7202522__F5 USP22-pivot gene-module-pathway network suggesting USP22 could affect multiple pathways by up-regulating UBC ENSG00000124422 ENSG00000104343 ENSG00000106367 ENSG00000198833 ENSG00000134982 ENSG00000160087 ENSG00000090674 ENSG00000221838 ENSG00000077721 ENSG00000126261 ENSG00000101224 ENSG00000117399 ENSG00000094804 ENSG00000150991 ENSG00000156587 ENSG00000136997 ENSG00000125686 ENSG00000123374 ENSG00000134243 ENSG00000135828 ENSG00000116661 ENSG00000095794 ENSG00000138760 PMC6458165__F1 Networks related to immune modulation and inflammatory response ENSG00000099985 ENSG00000167604 ENSG00000120889 ENSG00000116337 ENSG00000158050 ENSG00000291368 PMC6458165__F2 Ingenuity pathway analysis networks related to neurological disease are presented in this figure (A,B) ENSG00000110711 ENSG00000127948 PMC2587085__F1 Targeting EGFR and Src Pathways in Head and Neck Cancer ENSG00000065361 ENSG00000291971 ENSG00000146648 ENSG00000178568 PMC5941822__F1 Insulin signaling pathway ENSG00000136997 PMC3152870__F4 Signalling pathway of type III interferons (IFNs) compared with type II and type I IFNs ENSG00000159128 ENSG00000213928 ENSG00000111537 ENSG00000115415 ENSG00000027697 PMC5154826__F2 Hedgehog Signaling in the Stomach ENSG00000178860 ENSG00000111537 ENSG00000125538 ENSG00000164690 PMC2905627__F7 Schematic diagram demonstrates intracellular signaling events in the Ras/ERK1/2 pathway as well as the upstream and downstream cascades activated by GDNF in the C18-4 cells ENSG00000123374 ENSG00000123268 PMC7341381__F1 Structure of the Slit/Robo protein ENSG00000168036 ENSG00000154134 ENSG00000185008 PMC4475536__F3 Mechanism of action of paclitaxel ENSG00000002330 ENSG00000172936 ENSG00000136869 PMC3172101__F1 New additions to the Hippo pathway in flies (a) and man (b) ENSG00000132471 ENSG00000126016 ENSG00000026508 PMC5447946__F5 ENOs and 14-3-3 in neurodegeneration ENSG00000162711 ENSG00000002330 ENSG00000122194 PMC3845023__F1 Sulfate assimilation pathway ENSG00000121073 ENSG00000157593 ENSG00000138801 PMC6425613__F6 Functional enrichment and gene network analysis ENSG00000120833 ENSG00000070193 ENSG00000134460 ENSG00000203710 ENSG00000160710 ENSG00000216490 ENSG00000182326 ENSG00000274619 ENSG00000173369 ENSG00000123496 ENSG00000181374 ENSG00000277263 ENSG00000115594 ENSG00000099985 ENSG00000242689 ENSG00000164761 ENSG00000137033 ENSG00000140968 ENSG00000000971 ENSG00000277804 ENSG00000185885 ENSG00000174516 ENSG00000167333 ENSG00000179344 ENSG00000173372 ENSG00000197296 ENSG00000288512 ENSG00000142089 ENSG00000168685 PMC12179084__F2 Key signalling pathways implicated in macrocephalic ASD ENSG00000198793 ENSG00000168036 ENSG00000100888 ENSG00000196712 PMC3497822__F7 The signaling pathway by which FSH promotes AKT activation in GCs ENSG00000033327 ENSG00000169047 ENSG00000145321 PMC11662456__F1 Figure demonstrates PPARG and its relation to signaling pathways ENSG00000124610 ENSG00000187837 PMC5187887__F1 Schematic diagram representing chromosomal DNA and the major components of the DDR signaling pathway (top) ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000123374 ENSG00000171791 ENSG00000139618 PMC5117143__F7 ATR is required to maintain G2/M checkpoint integrity and prevent apoptosis induced by proliferation-associated DNA damage ENSG00000149311 ENSG00000175054 PMC7181472__F5 Kunxian capsule in treating RA ENSG00000198793 ENSG00000175104 ENSG00000168610 ENSG00000069667 PMC7181472__F6 Mechanism of side effect caused by Tripterygium hypoglaucum hutch and the mechanism of alleviation compensated by the rest of herbs ENSG00000084093 ENSG00000178035 ENSG00000070669 ENSG00000007171 PMC10253306__F2 Interactions found in polyQ-containing ID hub proteins located in both cytoplasm and nucleus using protein interaction annotation of HPRD ENSG00000171720 PMC10253306__F3 Splicing Modulators Are Involved in Human Polyglutamine Diversification via Protein Complexes Shuttling between Nucleus and Cytoplasm ENSG00000094631 ENSG00000173805 ENSG00000070831 ENSG00000163914 ENSG00000165280 PMC8316605__F1 Cryo-EM: A new dawn in thyroid biology ENSG00000042832 ENSG00000165409 PMC8316605__F2 Cryo-EM: A new dawn in thyroid biology ENSG00000042832 ENSG00000165409 PMC8105667__F5 Transcriptome analysis identifies signaling pathways related to meat quality in broiler chickens – the extracellular matrix (ECM) receptor interaction signaling pathway ENSG00000136457 ENSG00000135218 ENSG00000110799 ENSG00000026508 PMC8599584__F6 KIF15 Promotes Progression of Castration Resistant Prostate Cancer by Activating EGFR Signaling Pathway ENSG00000070831 ENSG00000280610 ENSG00000138798 ENSG00000146648 PMC9179967__F4 Hedgehog Signaling: Linking Embryonic Lung Development and Asthmatic Airway Remodeling ENSG00000106571 ENSG00000134057 ENSG00000164690 ENSG00000128602 PMC8054134__F2 Sources of proline in RPE PMC2891965__F8 Updates in the characterization of the COX-2 pathways in human neutrophils ENSG00000226275 PMC8054134__F4 Proline generates GSH and NADPH to counter oxidative stress ENSG00000151376 ENSG00000065833 ENSG00000100033 PMC7113187__F8 Proposed mechanism of BMP6 signaling pathway regulated by PSMD14-ALK2 axis in colorectal cancers ENSG00000170365 ENSG00000198742 PMC10861954__F4 Apoptosis and Inflammatory Signal Pathways Associated with Unremitted ER Stress and UPR ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC5072394__F1 Viral evasion of intracellular DNA and RNA sensing ENSG00000088888 ENSG00000121060 ENSG00000276561 PMC3026989__F1 The innate immune induction pathway through RLR activation ENSG00000171855 ENSG00000276561 PMC8082775__F3 Nonsense-mediated RNA decay and its bipolar function in cancer ENSG00000128272 ENSG00000151012 ENSG00000144895 ENSG00000006062 PMC3497822__F1 The signaling pathway by which FSH promotes AKT activation in GCs ENSG00000033327 ENSG00000169047 ENSG00000145321 PMC4008642__F1 Molecular Pathways: BRAF Induces Bioenergetic Adaptation by Attenuating Oxidative Phosphorylation ENSG00000110711 ENSG00000157764 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC4021393__F2 Activation of the "Role of BRCA1 in DNA Damage Response’ pathways in NCR versus CR samples ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000111537 ENSG00000095002 ENSG00000123268 ENSG00000156273 PMC10861954__F3 Unfolded Protein Response ENSG00000128272 ENSG00000144895 PMC7944059__F7 Kyoto Encyclopedia of Genes and Genomes pathway map illustrating differentially expressed genes (DEGs), as identified by protein-protein interaction network analysis using STRING ENSG00000157404 ENSG00000112964 ENSG00000088992 ENSG00000182667 PMC3109408__F2 Simplified diagram of Kynurenine pathway: during neuroinflammation, 95% of the dietary tryptophan is metabolized along the KP within the brain PMC12094478__F3 Mechanism of EVs in AKI ENSG00000073754 ENSG00000142082 ENSG00000079999 PMC8358851__F1 Drivers of phenotypic variation in cartilage: Circadian clock genes ENSG00000112977 ENSG00000105516 PMC3411757__F1 Modular Nature of Dendritic Cell Responses to Commensal and Pathogenic Fungi ENSG00000104856 ENSG00000187608 ENSG00000187796 ENSG00000089127 ENSG00000291971 ENSG00000115415 ENSG00000163914 ENSG00000102970 ENSG00000197943 ENSG00000112149 ENSG00000135828 ENSG00000115009 ENSG00000164342 PMC6747549__F1 Schematic summary of the molecular pathways of F ENSG00000181847 ENSG00000125538 ENSG00000168036 ENSG00000172936 PMC9520027__F11 Identification of lysophosphatidic acid in serum as a factor that promotes epithelial apical junctional complex organization ENSG00000130202 ENSG00000163914 ENSG00000168036 ENSG00000198670 PMC6487480__F1 Polyamine metabolism and cancer: treatments, challenges and opportunities ENSG00000088826 ENSG00000148832 ENSG00000198931 ENSG00000099810 ENSG00000118520 PMC4326377__F10 Activation of BV2 microglia could trigger a strong inflammatory reaction in PC12 cell apoptosis by toll-like receptor signaling pathway ENSG00000172936 ENSG00000136869 PMC395917__F5 BMP4 and LIF signaling in pluripotency ENSG00000170365 ENSG00000128342 ENSG00000168610 PMC9549772__F2 Chinese Herbal Medicines for Diabetic Nephropathy Fibrosis Treatment ENSG00000168036 PMC7348083__F2 Heat shock protein 90 inhibition and multi‐target approach to maximize cardioprotection in ischaemic injury ENSG00000284774 ENSG00000105401 ENSG00000079999 PMC11884866__F10 Diagram illustrates the role of PCBP2 in immune evasion in prostate cancer ENSG00000183735 PMC3770300__F1 Computational framework of 3D vascularized bone regeneration within a porous biodegradable CaP scaffold ENSG00000178860 PMC1895551__F1 Prosurvival signaling pathways and their downstream targets ENSG00000002330 ENSG00000164305 PMC8674840__F5 ICP22/IE63 Mediated Transcriptional Regulation and Immune Evasion: Two Important Survival Strategies for Alphaherpesviruses ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC5607427__F6 Model of Syk and SFK signaling in B ENSG00000070831 PMC3338536__F4 TDP-43 Identified from a Genome Wide RNAi Screen for SOD1 Regulators ENSG00000150991 ENSG00000139187 ENSG00000104969 ENSG00000087365 ENSG00000198056 ENSG00000108671 ENSG00000106628 PMC3291304__F1 Protein quality control systems are potential targets for mechanism-based treatments of demyelinating Charcot-Marie-Tooth disease (CMT) ENSG00000158887 ENSG00000101557 PMC4714209__F1 Biosynthesis of Sec on its tRNA ENSG00000179988 PMC8822596__F2 Ferroptosis in cancer and cancer immunotherapy ENSG00000076554 ENSG00000167468 ENSG00000102967 ENSG00000115107 ENSG00000057663 PMC8822596__F3 Ferroptosis in cancer and cancer immunotherapy ENSG00000186575 ENSG00000151012 ENSG00000167468 ENSG00000072274 ENSG00000086991 ENSG00000111684 ENSG00000079999 PMC8803838__F2 Neutrophils in chronic inflammatory diseases ENSG00000162711 ENSG00000150782 ENSG00000081041 ENSG00000100448 ENSG00000163739 ENSG00000125538 ENSG00000204936 ENSG00000005381 PMC8113860__F3 Crosstalk and regulation of innate immune cells in the esophageal cancer tumor microenvironment ENSG00000169245 ENSG00000108691 ENSG00000081041 ENSG00000198053 ENSG00000161921 ENSG00000138755 ENSG00000163734 ENSG00000189403 ENSG00000168610 ENSG00000115009 PMC5385394__F1 Major pathways associated with pancreatic ductal adenocarcinoma and site of action of current treatments ENSG00000198793 ENSG00000146648 PMC4123742__F3 Current model for replication-independent ICL repair ENSG00000012061 ENSG00000130997 ENSG00000136936 ENSG00000122008 PMC6749452__F8 The metabolic pathway networks of particularly significant potential biomarkers for the therapeutic effect of p-b4 on MSU crystal-induced GA rats ENSG00000283887 ENSG00000119537 ENSG00000275565 PMC8333862__F1 NAD+ Homeostasis in Diabetic Kidney Disease ENSG00000105835 ENSG00000278488 PMC8500707__F1 Genomic Landscape of HIV-Associated Plasmablastic Lymphoma ENSG00000148400 ENSG00000136997 ENSG00000026508 PMC9697247__F1 Selective Activation of the Wnt-Signaling Pathway as a Novel Therapy for the Treatment of Diabetic Retinopathy and Other Retinal Vascular Diseases ENSG00000162337 ENSG00000134982 ENSG00000106025 ENSG00000168036 PMC2720065__F8 Proposed signaling pathway of mmLDL-induced, TLR4/Syk-dependent ROS generation and proinflammatory cytokine expression ENSG00000170458 ENSG00000172936 ENSG00000136869 PMC7974260__F2 Representative diagram of circRNAs that interact with the circRNA-miRNA-mRNA regulatory network/RBPs and regulate oncogene or tumor suppressor signaling pathways ENSG00000112715 ENSG00000180357 ENSG00000168522 ENSG00000150630 PMC3161675__F3 Signal Transduction Involving the Dmp1 Transcription Factor and its Alteration in Human Cancer ENSG00000168283 ENSG00000121068 ENSG00000135446 ENSG00000136997 ENSG00000152592 ENSG00000135111 PMC10511911__F5 Regulation of insecticide resistance mechanisms involves epi-transcriptome signals, detoxification signaling pathways, and long non-coding RNAs (lncRNAs) ENSG00000106546 ENSG00000079999 PMC8295591__F2 HIV-1 Hijacking of Host ATPases and GTPases That Control Protein Trafficking ENSG00000099901 ENSG00000103769 ENSG00000164163 PMC6976902__F1 miR-135a Inhibits the Invasion and Migration of Esophageal Cancer Stem Cells through the Hedgehog Signaling Pathway by Targeting Smo ENSG00000128602 PMC5274667__F6 Cross talk between lipid/glucidic metabolism and cancer ENSG00000167772 ENSG00000132855 PMC5274667__F3 Molecular mechanism governing ANGPTL4-mediated TG hydrolysis ENSG00000277494 ENSG00000167772 ENSG00000042832 PMC8850798__F8 Selenium binding protein 1 inhibits tumor angiogenesis in colorectal cancers by blocking the Delta-like ligand 4/Notch1 signaling pathway ENSG00000128917 ENSG00000148400 ENSG00000114315 PMC2959101__F4 Schematic diagram of NELL-1 signaling pathways in osteoblast cells ENSG00000170365 ENSG00000137834 PMC4123742__F7 Advances in Understanding the Complex Mechanisms of DNA Interstrand Cross-Link Repair ENSG00000012061 ENSG00000115008 ENSG00000154920 ENSG00000188827 ENSG00000181544 ENSG00000187790 ENSG00000115392 ENSG00000112130 ENSG00000131944 ENSG00000012048 ENSG00000175054 ENSG00000144554 ENSG00000197299 ENSG00000051180 ENSG00000276787 PMC6555892__F1 MINA Workflow ENSG00000134460 ENSG00000065357 ENSG00000138378 ENSG00000138755 ENSG00000115267 ENSG00000110324 ENSG00000145782 ENSG00000168811 ENSG00000146648 PMC6200076__F1 Mechanisms of resistance to BRAF and MEK inhibitors and clinical update of US Food and Drug Administration-approved targeted therapy in advanced melanoma ENSG00000157764 ENSG00000198793 ENSG00000118515 PMC8263687__F8 Novel mechanism driving poor-prognostic gastric cancer: overexpression of the transcription factor Krüppel-like factor 16 promotes growth and metastasis of gastric cancer through regulating the Notch pathway ENSG00000170558 ENSG00000168036 ENSG00000123374 ENSG00000129911 ENSG00000197614 PMC5795269__F1 Nicotinamide adenine dinucleotide biosynthetic pathway ENSG00000105835 PMC6896717__F8 The schematic model of the process of regulating Akt/mTOR signaling by NL3 PMC7555474__F5 Rap1 promotes tumor progression via disruption of E-cadherin-mediated cell adhesion ENSG00000076864 ENSG00000170558 PMC9687982__F1 Pyroptosis: A Newly Discovered Therapeutic Target for Ischemia-Reperfusion Injury ENSG00000163568 ENSG00000091592 ENSG00000091106 PMC8514845__F2 Scaling the tips of the ALPS ENSG00000168610 PMC10525645__F1 Abnormalities in Copper Status Associated with an Elevated Risk of Parkinson’s Phenotype Development ENSG00000173163 ENSG00000173992 ENSG00000138495 ENSG00000123191 ENSG00000177556 PMC5747363__F2 Molecular targets of and mechanisms of resistance to major antimalarial drugs ENSG00000228716 ENSG00000095059 ENSG00000102967 PMC4506514__F1 Integrated genetic and epigenetic analysis defines novel molecular subgroups in rhabdomyosarcoma ENSG00000149311 ENSG00000160867 ENSG00000135446 ENSG00000115904 ENSG00000121879 ENSG00000139687 ENSG00000196712 PMC7339444__F8 Pcdh8 in Wnt/PCP signaling in Xenopus ENSG00000136099 ENSG00000100592 PMC10525645__F2 Simplified scheme for the conversion of food-derived copper into biovaluable copper ENSG00000138495 ENSG00000123191 ENSG00000177556 ENSG00000163631 PMC6539971__F1 Microtubule-associated protein 1 light chain 3 (LC3)-P62 autophagy signaling pathway ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC11395544__F9 Oral Administration of Probiotic Bifidobacterium breve Ameliorates Tonic–Clonic Seizure in a Pentylenetetrazole-Induced Kindling Mouse Model via Integrin-Linked Kinase Signaling ENSG00000168036 ENSG00000164305 PMC12146023__F2 Casein kinase 1 epsilon (CK1E) as a potential therapeutic target in chronic liver disease ENSG00000183735 ENSG00000281324 ENSG00000106571 ENSG00000162337 ENSG00000134982 ENSG00000169710 ENSG00000168036 ENSG00000131323 ENSG00000146648 PMC8443620__F2 Metabolic capabilities in three new actinobacterial classes ENSG00000172005 PMC3721281__F2 Asparagine-linked glycosylation pathway ENSG00000101901 ENSG00000000419 ENSG00000139133 ENSG00000033011 ENSG00000163933 ENSG00000088035 ENSG00000120697 ENSG00000214160 PMC3219404__F1 Putative involvement of the receptor for advanced glycation endproducts (RAGE) during infection ENSG00000163221 ENSG00000189403 ENSG00000162692 PMC4087161__F2 Phosphorylation of Foxo1 at S253 by Akt promotes Foxo1 cytoplasmic retention and ubiquitination, which serves as a central mechanism controlling Foxo1 stability and activity () ENSG00000157540 ENSG00000126457 ENSG00000283100 PMC12057185__F2 Processes of the three major classes for protein lipidation ENSG00000163914 ENSG00000116237 PMC9503909__F8 Fractionated Proton Irradiation Does Not Impair Hippocampal-Dependent Short-Term or Spatial Memory in Female Mice ENSG00000188486 ENSG00000185883 ENSG00000128654 ENSG00000159720 ENSG00000246705 ENSG00000126267 ENSG00000179820 ENSG00000113648 PMC9629566__F3 Niloticin binds to MD-2 to promote anti-inflammatory pathway activation in macrophage cells ENSG00000172936 ENSG00000136869 ENSG00000142224 PMC12057185__F7 Cohesive model of lipidation in the TME ENSG00000019991 ENSG00000186716 ENSG00000136869 ENSG00000231179 ENSG00000204520 PMC12057185__F5 S-palmitoylation within the TME ENSG00000278718 ENSG00000163958 ENSG00000188706 ENSG00000153786 ENSG00000204160 ENSG00000198793 ENSG00000163812 ENSG00000156599 ENSG00000177054 PMC12057185__F6 S-prenylation within the TME ENSG00000126016 ENSG00000130038 ENSG00000163914 ENSG00000155792 ENSG00000197992 ENSG00000067900 ENSG00000146648 PMC12057185__F3 Comprehensive kinetic model illustrates dual lipidation interplay within the TME signaling pathways ENSG00000088888 ENSG00000213658 ENSG00000134982 ENSG00000010810 PMC12057185__F4 N-myristoylation in the TME ENSG00000070193 ENSG00000151726 ENSG00000164430 ENSG00000002330 ENSG00000143761 ENSG00000291971 ENSG00000186716 ENSG00000198793 ENSG00000149357 ENSG00000168610 ENSG00000010671 ENSG00000026103 PMC6429383__F7 Compound-target network of 3DC2ME ENSG00000228716 ENSG00000157404 ENSG00000066926 ENSG00000143839 ENSG00000171791 ENSG00000069667 ENSG00000126218 ENSG00000122025 ENSG00000151834 ENSG00000183134 ENSG00000095303 ENSG00000115138 ENSG00000196639 ENSG00000170231 ENSG00000001626 ENSG00000101162 ENSG00000142192 ENSG00000076555 ENSG00000007171 ENSG00000132170 ENSG00000143387 ENSG00000274247 ENSG00000067191 ENSG00000136160 ENSG00000127948 ENSG00000182389 ENSG00000291971 ENSG00000138798 ENSG00000112715 ENSG00000166851 ENSG00000163631 ENSG00000276825 ENSG00000077150 ENSG00000129214 ENSG00000196549 ENSG00000128052 ENSG00000166501 ENSG00000111142 ENSG00000120903 ENSG00000180720 ENSG00000259207 ENSG00000100906 ENSG00000081248 ENSG00000006283 ENSG00000073756 ENSG00000087460 ENSG00000169836 ENSG00000066468 ENSG00000109163 ENSG00000167535 ENSG00000163131 ENSG00000094755 ENSG00000111452 ENSG00000108878 ENSG00000157445 ENSG00000128602 ENSG00000196689 ENSG00000074803 ENSG00000262243 PMC4672393__F1 Complement System and Antibody Mediated Transplant Rejection ENSG00000203710 ENSG00000244731 ENSG00000236625 PMC4109688__F2 Toward T Cell Protein–Protein Interaction Activity Relevant to Alopecia Areata ENSG00000291603 ENSG00000213658 PMC8113373__F4 CircRNAs: role in human diseases and potential use as biomarkers ENSG00000148773 ENSG00000087586 ENSG00000150457 ENSG00000131023 PMC5496785__F1 Restore the brake on tumor progression ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC4985808__F7 Transcriptomic analysis of heteromorphic stamens in Cassia biscapsularis L ENSG00000110395 PMC7546716__F1 T-cell polarisation in COVID-19IL-33 released from virus-damaged cells might induce dysregulated GATA3+Foxp3+ Tregs and promote IL-2 production by dendritic cells, resulting in further expansion of Tregs ENSG00000162711 ENSG00000137033 ENSG00000049768 ENSG00000121807 ENSG00000168610 ENSG00000169245 ENSG00000186810 ENSG00000108691 ENSG00000111537 ENSG00000138755 ENSG00000108700 ENSG00000107485 ENSG00000172936 PMC8113373__F2 CircRNAs: role in human diseases and potential use as biomarkers ENSG00000004975 ENSG00000078747 ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC9709075__F6 Transcriptomic comparison of primary human lung cells with lung tissue samples and the human A549 lung cell line highlights cell type specific responses during infections with influenza A virus ENSG00000171855 ENSG00000188379 ENSG00000138035 ENSG00000185201 ENSG00000185885 ENSG00000111331 PMC7893118__F1 TGFB signaling ENSG00000137834 PMC7602704__F1 Involvement of TPMT on the thiopurine metabolic pathway ENSG00000106348 ENSG00000137364 ENSG00000138356 ENSG00000158125 PMC6170637__F4 Animal and plant cells ENSG00000291931 ENSG00000162711 ENSG00000167207 ENSG00000091106 ENSG00000106100 PMC8640216__F1 Interplay of the Unfolded Protein Response in Neurodegenerative Diseases: A Therapeutic Role of Curcumin ENSG00000128272 ENSG00000144895 PMC6170637__F3 Animal and plant cells ENSG00000172005 ENSG00000136869 ENSG00000132341 PMC9343597__F1 Present and Future: Crosstalks Between Polycystic Ovary Syndrome and Gut Metabolites Relating to Gut Microbiota ENSG00000129214 ENSG00000131096 PMC7002574__F4A Pathway and network analysis of more than 2500 whole cancer genomes ENSG00000167258 ENSG00000121989 ENSG00000253293 ENSG00000134982 ENSG00000159388 ENSG00000121067 ENSG00000129514 ENSG00000061676 ENSG00000116251 ENSG00000124762 ENSG00000136826 ENSG00000166164 ENSG00000134086 ENSG00000125398 ENSG00000136997 ENSG00000116350 ENSG00000108375 ENSG00000220205 ENSG00000139687 ENSG00000064012 ENSG00000196712 ENSG00000109670 ENSG00000129474 ENSG00000148400 ENSG00000164761 ENSG00000189056 ENSG00000126012 ENSG00000139618 ENSG00000106829 ENSG00000111596 ENSG00000224320 ENSG00000175745 ENSG00000143476 ENSG00000107485 ENSG00000067955 ENSG00000146648 ENSG00000101752 ENSG00000127616 ENSG00000189079 ENSG00000163939 ENSG00000168036 ENSG00000160007 ENSG00000163631 ENSG00000011422 ENSG00000122565 ENSG00000100504 ENSG00000124181 ENSG00000133818 ENSG00000215301 ENSG00000133895 ENSG00000142627 ENSG00000005339 ENSG00000157764 ENSG00000116044 ENSG00000135100 ENSG00000081237 ENSG00000134363 ENSG00000124766 ENSG00000156976 ENSG00000143933 ENSG00000273686 ENSG00000147274 ENSG00000177565 ENSG00000079999 ENSG00000149311 ENSG00000101972 ENSG00000115524 ENSG00000291748 ENSG00000164362 ENSG00000055609 ENSG00000120075 ENSG00000111786 ENSG00000152518 ENSG00000150630 ENSG00000165494 PMC8996410__F3 Proteolysis-targeting chimeras (PROTACs) in cancer therapy ENSG00000169925 ENSG00000141867 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000146648 ENSG00000166164 PMC12146603__F3 Neurotransmitter pathway affected by genetic 5‐HTT inactivation at PND8 ENSG00000124493 ENSG00000115419 PMC6606846__F2 Regulation of (p)ppGpp metabolism in Gamma-proteobacteria ENSG00000261701 ENSG00000173039 PMC11313179__F7 Illustration of the most significant regulated target genes related to PPAR signaling pathway ENSG00000214456 PMC9168430__F3 Gut Microbial Dysbiosis and Cognitive Impairment in Bipolar Disorder: Current Evidence ENSG00000129167 ENSG00000106546 PMC4568143__F1 From bench to bedside: what do we know about Hormone Receptor-positive and Human Epidermal Growth Factor Receptor 2-positive breast cancer? ENSG00000113905 ENSG00000163235 ENSG00000146648 PMC4150834__F2 MC1R, the cAMP pathway and the response to solar UV: Extending the horizon beyond pigmentation ENSG00000141480 PMC5809511__F4 Non-canonical Wnt signaling at the primary cilium ENSG00000104290 ENSG00000011143 PMC8238251__F1 Endogenous AGE formation and pathobiological actions of RAGE receptor ligands ENSG00000173599 ENSG00000189403 PMC8111493__F1 Regulatory T cells in ischemic stroke ENSG00000108702 ENSG00000179934 ENSG00000109321 ENSG00000100985 ENSG00000168610 ENSG00000146648 ENSG00000115009 ENSG00000112486 PMC6398892__F2 Regulation mechanism of ECM/integrin/EphA1‐mediated cell adhesion ENSG00000284816 PMC5714692__F2 Nutrient regulation of pancreatic Beta-cell proliferation ENSG00000135218 ENSG00000042832 PMC5845716__F1 TANK-binding kinase 1 (TBK1) in humoral responses ENSG00000183735 ENSG00000164430 ENSG00000123240 ENSG00000088888 ENSG00000145321 ENSG00000136869 ENSG00000164342 PMC11809008__F9 HSPA1A inhibits pyroptosis and neuroinflammation after spinal cord injury via DUSP1 inhibition of the MAPK signaling pathway ENSG00000278718 ENSG00000162711 PMC6064949__F10 A model depicting the mode that hypoxia exacerbats acute lung injury (ALI) via the toll-like receptor 4 (TLR4) signaling pathway and the protective effect of hypoxia-inducible factor 1 alpha (HIF-1A) ENSG00000150782 ENSG00000170458 ENSG00000125538 ENSG00000136869 PMC1216340__F10 Schematic model depicting potential mechanism that might contribute to epithelial-specific regulation of the CFTR gene ENSG00000100811 ENSG00000001626 PMC5435082__F1 Selection in Europeans on Fatty Acid Desaturases Associated with Dietary Changes ENSG00000134824 ENSG00000149485 PMC64811__F2 Failure of endogenous regulation of wound-healing in idiopathic pulmonary fibrosis (IPF) PMC5903677__F3 Therapeutic targets for brain injury for nanoparticle mediated drug delivery ENSG00000214285 PMC3267701__F1 Amyloid precursor protein (APP) processing pathway ENSG00000146648 PMC8802892__F5 Transcriptomic and Metabolomic Analyses Reveal Inhibition of Hepatic Adipogenesis and Fat Catabolism in Yak for Adaptation to Forage Shortage During Cold Season ENSG00000130164 ENSG00000042832 ENSG00000099194 PMC12090542__F1 Five signalling pathways in regulating the immune microenvironment of DW ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000291971 ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC2963177__F2 Integration of non-SMAD and SMAD signaling in TGFB1-induced plasminogen activator inhibitor type-1 gene expression in vascular smooth muscle cells ENSG00000146648 PMC8949198__F1 Oxidative Stress in Arterial Hypertension (HTN): The Nuclear Factor Erythroid Factor 2-Related Factor 2 (Nrf2) Pathway, Implications and Future Perspectives ENSG00000178573 ENSG00000167363 ENSG00000079999 PMC7021762__F7 Components of GFI on KEGG gene networks ENSG00000077150 ENSG00000157764 ENSG00000198793 ENSG00000140285 ENSG00000173535 ENSG00000099860 ENSG00000169242 ENSG00000121879 ENSG00000146648 PMC5122403__F8 Increased translocation of antigens to endosomes and TLR4 mediated endosomal recruitment of TAP contribute to nicotine augmented cross-presentation ENSG00000198793 ENSG00000172936 ENSG00000136869 PMC9166893__F8 Essential role of CK2A for the interaction and stability of replication fork factors during DNA synthesis and activation of the S-phase checkpoint ENSG00000188486 ENSG00000175054 ENSG00000164053 ENSG00000092853 ENSG00000123374 ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000166508 ENSG00000093009 PMC5777733__F12 Targeting the SUMO pathway as a novel treatment for anaplastic thyroid cancer ENSG00000142230 ENSG00000033800 PMC9445673__F8 Gene network downstream plant stress response modulated by peroxisomal H2O2 ENSG00000133265 ENSG00000102878 ENSG00000178363 ENSG00000090376 ENSG00000160202 PMC5204325__F1 Cross talk between the transforming growth factor B (TGFB) family and Wnt signaling at multiple points ENSG00000134982 ENSG00000198742 ENSG00000168036 PMC8108031__F1 Repurposing metformin for the treatment of gastrointestinal cancer ENSG00000198793 ENSG00000140443 PMC6430635__F4 Different subcellular sources of MHC-I molecules for cross-presentation ENSG00000019582 ENSG00000116521 ENSG00000103769 PMC6430635__F5 Convergence of three vesicular pathways of endocytic traffic on the cross-presentation compartment in dendritic cells ENSG00000265808 ENSG00000103769 ENSG00000172936 PMC3757665__F2 Nrf2-Keap1 signaling pathway PMC5509726__F3 Protein-protein interaction networks of metabolism related pathway enriched genes ENSG00000130957 ENSG00000262785 ENSG00000121578 ENSG00000064225 ENSG00000162630 ENSG00000134982 ENSG00000008513 ENSG00000172955 ENSG00000145384 ENSG00000156966 ENSG00000117411 ENSG00000179913 ENSG00000132170 ENSG00000134824 ENSG00000112378 ENSG00000183778 ENSG00000130383 ENSG00000159399 ENSG00000169299 PMC6910162__F1 Overview of metabolic pathways in atherosclerosis and trained immunity ENSG00000135218 ENSG00000160179 ENSG00000159399 ENSG00000026103 PMC8830041__F7 Interleukin-17A pretreatment attenuates the anti-hepatitis B virus efficacy of interferon-alpha by reducing activation of the interferon-stimulated gene factor 3 transcriptional complex in hepatitis B virus-expressing HepG2 cells ENSG00000184979 ENSG00000187608 ENSG00000105397 ENSG00000175104 ENSG00000177663 ENSG00000163702 ENSG00000172183 PMC5509726__F6 Protein-protein interaction networks of lipid metabolism related pathway enriched genes ENSG00000138308 ENSG00000065357 ENSG00000117215 ENSG00000135218 ENSG00000161905 ENSG00000188257 ENSG00000138823 ENSG00000152642 ENSG00000276870 ENSG00000105223 PMC2801624__F1 A home away from home: challenges and opportunities in engineering in vitro muscle satellite cell niches ENSG00000009709 ENSG00000111049 ENSG00000074181 PMC8790554__F2 Celiac disease: From genetics to epigenetics ENSG00000253352 PMC9113239__F6 Fabrication and evaluation of a BMP-2/dexamethasone co-loaded gelatin sponge scaffold for rapid bone regeneration ENSG00000170365 ENSG00000125968 PMC8117216__F1 Repositioning of Antiparasitic Drugs for Tumor Treatment ENSG00000105613 ENSG00000149269 ENSG00000198793 ENSG00000272398 ENSG00000026508 PMC8113030__F3 Redox regulation of the insulin signalling pathway PMC3646677__F1 B-Raf protein and signaling pathways ENSG00000122025 ENSG00000157764 ENSG00000198793 ENSG00000203710 ENSG00000047849 ENSG00000146648 ENSG00000117322 PMC8113030__F4 Redox regulation of the insulin signalling pathway PMC5958133__F6 Gene transcription in key nutrient metabolic pathways involved in lipid synthesis between L ENSG00000099194 ENSG00000026103 PMC8113030__F5 Redox regulation of the insulin signalling pathway ENSG00000117020 ENSG00000115457 ENSG00000167779 ENSG00000169047 ENSG00000141753 ENSG00000118515 ENSG00000146678 ENSG00000115461 ENSG00000140443 PMC9389448__F2 Modes of action and diagnostic value of miRNAs in sepsis ENSG00000128191 ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC9167543__F2 MicroRNAs as the critical regulators of cell migration and invasion in thyroid cancer ENSG00000134982 ENSG00000177606 ENSG00000168036 ENSG00000125084 PMC9389448__F3 Modes of action and diagnostic value of miRNAs in sepsis ENSG00000170458 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC3852967__F3 Interaction network of genes differentially expressed in response to glatiramer acetate (GA) ENSG00000105641 ENSG00000125735 ENSG00000147168 ENSG00000081237 ENSG00000213402 ENSG00000197272 ENSG00000163736 ENSG00000127191 ENSG00000150782 ENSG00000169245 ENSG00000291972 ENSG00000165841 ENSG00000174233 ENSG00000138755 ENSG00000285318 ENSG00000115138 ENSG00000146678 ENSG00000174059 ENSG00000162692 ENSG00000126264 ENSG00000143184 PMC6886858__F6 A Bayesian gene network reveals insight into the JAK-STAT pathway in systemic lupus erythematosus ENSG00000115415 ENSG00000263513 ENSG00000155660 ENSG00000172123 ENSG00000184898 ENSG00000125347 ENSG00000276561 ENSG00000073737 PMC6441925__F1 DNA repair pathways with mutated genes highlighted ENSG00000149311 ENSG00000012048 ENSG00000136492 ENSG00000083093 ENSG00000132646 ENSG00000035928 ENSG00000095002 ENSG00000064933 ENSG00000139618 PMC7418032__F6 Autophagic Clearance of Active and Damaged Mitochondria in HSCs ENSG00000152348 ENSG00000198793 ENSG00000158828 ENSG00000112561 ENSG00000197785 ENSG00000145782 ENSG00000057663 PMC8203498__F1 Representation of the signaling pathways involved in B-cell clonogenicity induced by clonogenic vp17s ENSG00000123374 ENSG00000095002 ENSG00000146648 PMC7921306__F1 Genomic and non-genomic mechanisms of glucocorticoids PMC3475172__F1 Model of canonical eukaryotic translation initiation pathway ENSG00000144895 PMC6886858__F4 A Bayesian gene network reveals insight into the JAK-STAT pathway in systemic lupus erythematosus ENSG00000169245 ENSG00000108691 ENSG00000115415 ENSG00000115267 ENSG00000166851 ENSG00000125347 ENSG00000276561 ENSG00000140464 ENSG00000026103 PMC3243350__F1 Biosynthetic pathway of oxylipins in Arabidopsis ENSG00000122882 ENSG00000100473 PMC6942823__F6 Inhibitory effect of Tt-ME in RAW264.7 macrophages ENSG00000291971 ENSG00000172936 ENSG00000136869 ENSG00000168610 ENSG00000184216 PMC3929501__F1 a) Digrammatic representation of follicle growth from the non-proliferating pool of primordial follicles PMC2712786__F1 Pathways of extrinsic and intrinsic apoptosis, highlighting roles of Bcl-2 family members ENSG00000100290 ENSG00000002330 ENSG00000135116 ENSG00000104081 PMC10138595__F3 PGE2 Promotes Immunoregulation through Cross-Regulation between Beta-catenin and NFKB by Activating the Wnt-Beta-catenin Signaling Pathways ENSG00000134982 ENSG00000168036 PMC3064126__F6 PHEX, DMP1, matrix extracellular phosphoglycoprotein (MEPE), and ASARM peptides are proposed to dynamically regulate FGF23 expression in bone ENSG00000118972 ENSG00000205221 ENSG00000152592 PMC10138595__F1 Cytokine Storm and ALI/ARDS Induced by Influenza Virus Infection ENSG00000189403 ENSG00000172936 ENSG00000276561 PMC12016489__F8 Two major complexes of the mTOR signaling pathway and their pathways ENSG00000155792 ENSG00000167965 PMC6030168__F7 Hypothetical model showing that imbalanced LIMK1 and LIMK2 expression activates the WNT/Beta-catenin pathway and leads to CRC progression and EMT-induced metastasis ENSG00000106683 ENSG00000168036 ENSG00000182541 PMC1964754__F6 Furin in development, homeostasis and disease ENSG00000087245 ENSG00000140564 ENSG00000135960 PMC4440819__F7 DA-Raf-Mediated Suppression of the Ras—ERK Pathway Is Essential for TGFB1-Induced Epithelial—Mesenchymal Transition in Alveolar Epithelial Type 2 Cells PMC7072529__F1 Hypothesised regulation of extracellular matrix composition by the cilium and ciliary proteins ENSG00000100234 ENSG00000109083 ENSG00000164066 ENSG00000157766 ENSG00000168374 ENSG00000128602 PMC5346543__F9 Diagrammatic presentation of the mechanism of EMAP-II in combination with TMZ suppressed malignant biological behaviors of GSCs via miR-590-3p/MACC1 inhibiting PI3K/AKT/mTOR signaling pathway ENSG00000198793 ENSG00000183742 PMC7696686__F6 The current working hypothesis ENSG00000087245 ENSG00000163914 ENSG00000158828 PMC6333051__F2 IL-6 signaling in the tumor cell of the bone marrow niche ENSG00000198793 ENSG00000168610 PMC5553399__F8 Proposed mechanism for G2 phase-specific nuclear export of CENP-F ENSG00000117724 ENSG00000069248 PMC3851442__F2 Transposable elements and their potential role in complex lung disorder ENSG00000134982 PMC9420447__F7 Alpha-Momorcharin Inhibits Proinflammatory Cytokine Expression by M1 Macrophages but Not Anti-Inflammatory Cytokine Expression by M2 Macrophages ENSG00000183735 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC8801426__F2 G Protein-Coupled Receptor Kinase 2 as Novel Therapeutic Target in Fibrotic Diseases ENSG00000115415 ENSG00000125347 PMC10031257__F3 Focal adhesion proteins in skeleton and diseases ENSG00000154736 ENSG00000125398 ENSG00000291971 ENSG00000166670 ENSG00000168610 PMC7760926__F1 Role of oxidative stress in muscle wasting during cancer cachexia ENSG00000128272 ENSG00000198793 PMC6492276__F2 Biosynthesis of O-GlcNAc and UDP-GlcNAc ENSG00000100522 ENSG00000147162 ENSG00000198380 ENSG00000198408 PMC9408832__F3 Targeting the Sphingolipid Rheostat in Gliomas ENSG00000167769 ENSG00000070610 ENSG00000285281 ENSG00000135587 ENSG00000143418 ENSG00000139624 ENSG00000100422 ENSG00000198964 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000143753 ENSG00000292130 ENSG00000164023 ENSG00000188611 ENSG00000166224 ENSG00000078124 ENSG00000119537 ENSG00000148154 ENSG00000168350 ENSG00000163082 PMC11896785__F2 Mass Spectrometry as a First-Line Diagnostic Aid for Congenital Disorders of Glycosylation ENSG00000000419 ENSG00000136152 ENSG00000164414 ENSG00000134851 ENSG00000153989 ENSG00000134910 ENSG00000120697 ENSG00000117682 ENSG00000136710 ENSG00000244045 ENSG00000160131 ENSG00000213380 ENSG00000168538 ENSG00000138821 ENSG00000173540 ENSG00000114850 ENSG00000198856 ENSG00000166685 ENSG00000168282 ENSG00000185344 ENSG00000102158 ENSG00000157353 ENSG00000180879 ENSG00000163933 ENSG00000182220 ENSG00000214160 ENSG00000136908 ENSG00000177239 ENSG00000089597 ENSG00000101901 ENSG00000126091 ENSG00000104723 ENSG00000244038 ENSG00000139133 ENSG00000163527 ENSG00000088035 ENSG00000117620 ENSG00000164597 ENSG00000172339 ENSG00000130175 PMC3060320__F2 Schematic illustration of signalling within the type I interferon (IFN) system ENSG00000163512 ENSG00000188379 ENSG00000213928 ENSG00000048462 ENSG00000102871 ENSG00000150455 ENSG00000135341 ENSG00000121966 ENSG00000137080 ENSG00000161955 ENSG00000239732 ENSG00000177047 ENSG00000263528 ENSG00000228083 ENSG00000137265 ENSG00000233816 ENSG00000147896 ENSG00000120235 ENSG00000168310 ENSG00000136869 ENSG00000198933 ENSG00000186803 ENSG00000147885 ENSG00000120242 ENSG00000214042 ENSG00000164342 ENSG00000236637 ENSG00000124256 ENSG00000104365 ENSG00000140968 ENSG00000033800 ENSG00000115267 ENSG00000168040 ENSG00000234829 ENSG00000125347 ENSG00000168610 ENSG00000276561 ENSG00000186810 ENSG00000105397 ENSG00000118785 ENSG00000118503 ENSG00000172936 ENSG00000131323 PMC9399520__F7 Celastrol ameliorates osteoarthritis via regulating TLR2/NFKB signaling pathway ENSG00000172936 ENSG00000150455 PMC8721241__F3 Updated role of ABA in seed maturation, dormancy, and germination ENSG00000185386 ENSG00000108798 ENSG00000163788 PMC5157899__F4 PEP-mediated metabolism in thermogenic cells of S ENSG00000172005 PMC2731675__F3 FOLLICULAR HELPER T CELLS: LINEAGE AND LOCATION ENSG00000115008 ENSG00000186716 ENSG00000173599 ENSG00000145321 PMC4705593__F1 Cholesterol biosynthesis pathway ENSG00000160752 ENSG00000130164 ENSG00000113161 PMC7333652__F8 Microenvironment-related gene TNFSF13B predicts poor prognosis in kidney renal clear cell carcinoma ENSG00000063245 ENSG00000291971 ENSG00000198931 ENSG00000164167 ENSG00000143179 PMC8580647__F4 Spatial-Temporal Patterns and Inflammatory Factors of Bone Matrix Remodeling ENSG00000170365 ENSG00000163235 PMC7226777__F1 Principal functions of the 18-kDa translocator protein (TSPO): initiation of programmed cell death, including apoptosis, as well as regulation of the cell’s nuclear gene expression ENSG00000013441 ENSG00000136997 ENSG00000283060 PMC2812698__F1 Signalling pathways that regulate cell wall remodelling of Candida albicans ENSG00000070831 ENSG00000101871 PMC4572872__F2 Many anticancer agents mediate tumour cell killing though activation of the BCL-2-regulated apoptotic pathway ENSG00000002330 ENSG00000104081 PMC9650829__F2 Understanding the versatile roles and applications of EpCAM in cancers: from bench to bedside ENSG00000138795 ENSG00000119888 ENSG00000138798 ENSG00000170558 ENSG00000168036 ENSG00000146648 PMC9192945__F1 Myeloid Cells in GBM Immunosuppression ENSG00000168062 ENSG00000108691 ENSG00000170458 ENSG00000163739 ENSG00000169429 ENSG00000135404 ENSG00000100985 ENSG00000168610 PMC5639307__F7 Summary of the study results with pathway ENSG00000164690 ENSG00000128602 PMC8708027__F6 Signaling Pathway Inhibitors, miRNA, and Nanocarrier-Based Pharmacotherapeutics for the Treatment of Lung Cancer: A Review ENSG00000259207 ENSG00000135446 ENSG00000124766 ENSG00000105810 ENSG00000096717 ENSG00000146648 ENSG00000282899 PMC5012964__F3 Steroidogenic pathway ENSG00000086696 ENSG00000203859 ENSG00000203857 PMC8708027__F3 Signaling Pathway Inhibitors, miRNA, and Nanocarrier-Based Pharmacotherapeutics for the Treatment of Lung Cancer: A Review ENSG00000002330 ENSG00000198793 PMC6323488__F3 Different signaling pathways related to EGFR activation induced by CTGF/EGFR interaction ENSG00000134057 ENSG00000132646 ENSG00000123374 ENSG00000146648 PMC5012964__F2 Molecular pathways underlying the development of the male external genitalia ENSG00000070193 ENSG00000168036 ENSG00000164690 ENSG00000128714 PMC4352987__F3 Multiple signaling pathways regulate the expression and activity of Sox9 during chondrogenesis ENSG00000139219 ENSG00000125398 ENSG00000141448 ENSG00000130700 ENSG00000285109 ENSG00000164690 ENSG00000109705 ENSG00000110693 PMC4352987__F4 Different combinations of transcription factors drive tissue-specific gene expression in immature versus hypertrophic chondrocytes ENSG00000170608 ENSG00000141448 ENSG00000130700 ENSG00000285109 ENSG00000020633 ENSG00000168036 ENSG00000112715 ENSG00000081189 ENSG00000110693 ENSG00000139219 ENSG00000170365 ENSG00000125398 ENSG00000118785 ENSG00000157766 ENSG00000291761 ENSG00000109705 PMC4352987__F5 Regulatory pathways downstream of BMP, Fgf18, CNP, Ihh or PTHrP signaling control chondrocyte proliferation and hypertrophy ENSG00000115415 ENSG00000160584 ENSG00000156427 ENSG00000173786 ENSG00000291761 ENSG00000159899 ENSG00000163501 ENSG00000081189 PMC9695474__F3 Porcine Epidemic Diarrhea Virus: An Updated Overview of Virus Epidemiology, Virulence Variation Patterns and Virus–Host Interactions ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000172936 ENSG00000131323 ENSG00000125347 ENSG00000175104 ENSG00000146648 ENSG00000276561 ENSG00000164342 PMC8389606__F2 NFKB and Human Cancer: What Have We Learned over the Past 35 Years? ENSG00000104856 ENSG00000186716 ENSG00000172936 ENSG00000111321 ENSG00000083799 PMC8708027__F1 Signaling Pathway Inhibitors, miRNA, and Nanocarrier-Based Pharmacotherapeutics for the Treatment of Lung Cancer: A Review ENSG00000163235 ENSG00000146648 PMC7783549__F7 Comprehensive analysis of transcriptomics and metabolomics to understand triptolide-induced liver injury in mice ENSG00000291983 ENSG00000110711 ENSG00000117525 ENSG00000128272 ENSG00000002330 ENSG00000168040 ENSG00000127191 ENSG00000164305 ENSG00000084774 ENSG00000115317 ENSG00000026103 PMC7196462__F2 Roles of SMAD3 in the TGF‐B and the BMP pathway ENSG00000113360 PMC3632646__F2 Regulation of GLI1 the isoforms by the canonical and noncanonical pathways ENSG00000134853 ENSG00000150459 ENSG00000164690 ENSG00000128602 PMC5546320__F5 Oxygen Availability and Metabolic Adaptations ENSG00000177169 ENSG00000163141 ENSG00000128272 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC12154332__F1 Barrel-like structure of ABO forms ion channels in the cell membrane, allowing Ca2+ to enter the cell ENSG00000291971 ENSG00000096717 ENSG00000106459 PMC11605246__F8 Schematic explanation of the mechanism of action: the transformation into M2-like of spleen macrophages in patients with PH is activated, which in turn activates the Ras-Raf-MEK-ERK-c-Myc signaling pathway axis ENSG00000177575 ENSG00000135218 ENSG00000113520 PMC12086986__F7 Magnolin mitigates CXCL10‐induced skin ageing ENSG00000169245 ENSG00000186810 ENSG00000069482 PMC12154332__F2 Serotonin and BDNF initiate neurogenesis ENSG00000005882 PMC7843995__F5 CFMSN and associated drugs ENSG00000136997 ENSG00000171791 ENSG00000112715 PMC6825310__F4 Executable network model as seen in the BMA tool ENSG00000157557 ENSG00000134086 ENSG00000002330 ENSG00000135446 ENSG00000138798 ENSG00000136997 ENSG00000168036 ENSG00000123374 ENSG00000125084 PMC8750045__F1 Tight Control of Non-Canonical TGFB Pathways and MicroRNAs Downregulates Nephronectin in Podocytes ENSG00000198793 ENSG00000175104 ENSG00000135341 ENSG00000076604 PMC6912965__F1 Underlying mechanisms of Tregs in PAH ENSG00000204217 PMC6966641__F1 Major pathways involved in muscle loss in cancer cachexia ENSG00000198793 ENSG00000172936 PMC10853679__F7 Graphical abstract to present metabolic heterogeneity in central and peripheral tumour areas of LumA and LumB ENSG00000188257 ENSG00000121879 ENSG00000146648 PMC7106581__F2 Graphic summary of physiological activities of Fndc5/Irisin that are elicited through pathways other than MAP-kinase signaling ENSG00000177169 ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000168610 PMC7017070__F1 MiRNA processing pathway ENSG00000124571 ENSG00000128191 ENSG00000113360 PMC5855561__F9 Working Model for regulation of prostate cancer ENSG00000066294 ENSG00000125538 ENSG00000106546 PMC7757024__F2 SIRT1 regulates neuroendocrine secretion ENSG00000165409 ENSG00000096717 PMC7757024__F1 SIRT1 modulates glucose metabolism through regulating cell secretion ENSG00000175567 ENSG00000096717 PMC4090493__F6 Proposed mechanism by which -shogaol inhibits melanin biosynthesis PMC5716074__F7 “Prokaryotic Pathway” Is Not Prokaryotic: Noncyanobacterial Origin of the Chloroplast Lipid Biosynthetic Pathway Revealed by Comprehensive Phylogenomic Analysis ENSG00000173599 ENSG00000198670 ENSG00000026103 PMC6539782__F1 Carbohydrate and protein metabolisms ENSG00000151012 ENSG00000096717 PMC8897051__F2 Repurposing non-oncology small-molecule drugs to improve cancer therapy: Current situation and future directions ENSG00000198793 ENSG00000168036 ENSG00000168610 PMC5716074__F1 “Prokaryotic Pathway” Is Not Prokaryotic: Noncyanobacterial Origin of the Chloroplast Lipid Biosynthetic Pathway Revealed by Comprehensive Phylogenomic Analysis ENSG00000198670 ENSG00000167701 PMC2911501__F2 gp130-dependent cytokines promote axon regeneration and SOCS3 act as a critical negative regulator of the signaling pathway ENSG00000242689 ENSG00000169047 ENSG00000128342 ENSG00000168610 PMC2911501__F3 PTEN-regulated signaling pathway ENSG00000002330 ENSG00000198793 PMC7017070__F7 OncomiRs miR-221 and miR-210 and their impact on cancer cells ENSG00000105991 ENSG00000100985 ENSG00000196396 ENSG00000124762 ENSG00000062716 PMC7017070__F3 Important tumor suppressive miRNAs and their impact on cancer cells ENSG00000121966 PMC12007672__F8 Mechanistic illustration of KGF-2’s role in inhibiting inflammation and alleviating DED by regulating the HMGB1/TLR4 pathway ENSG00000162711 ENSG00000189403 ENSG00000136869 PMC3709783__F6 UV-induced cyclobutane dimers- structure (A) and repair by the Nucleotide Excision DNA Repair (NER) pathway (B) ENSG00000012061 ENSG00000134899 ENSG00000134574 ENSG00000136936 PMC4955940__F1 T-cell activation is regulated by antigen presentation, as well as stimulatory and inhibitory co-receptors ENSG00000291603 ENSG00000177606 PMC6960141__F10 Proposed mechanistic model of FA-97 ameliorates DSS-induced colitis against oxidative stress by activating Nrf2/HO-1 pathway ENSG00000181019 ENSG00000125538 ENSG00000136869 ENSG00000079999 PMC8733961__F4 5q35 duplication presents with psychiatric and undergrowth phenotypes mediated by NSD1 overexpression and mTOR signaling downregulation ENSG00000198793 PMC2895369__F1 High-flux and low-flux systems of electron transfer pathways ENSG00000182511 ENSG00000167468 PMC8879487__F1 Utility of Genomic Testing for Hyperphenylalaninemia ENSG00000139287 ENSG00000171759 ENSG00000116096 ENSG00000166228 PMC5788639__F6 Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement ENSG00000157764 PMC3061041__F1 Negative regulation of the IMD pathway ENSG00000083799 ENSG00000168040 ENSG00000177084 ENSG00000146648 PMC7611899__F1 Fibrosis development and signaling pathways ENSG00000198793 ENSG00000168036 ENSG00000136869 ENSG00000162924 ENSG00000137845 PMC5250671__F1 Oncogenic pathways in glioma and possibilities for pharmacological interventions, relevant for the models described in this article ENSG00000135446 ENSG00000198793 ENSG00000139687 PMC3757428__F2 Growth factors mediated mTORC1 and mTORC2 activation PMC3374088__F1 Caspase-8 has a crucial role in the regulation of DRs ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000285379 PMC8913526__F1 Helminth and Host Crosstalk: New Insight Into Treatment of Obesity and Its Associated Metabolic Syndromes ENSG00000125538 PMC11651451__F2 Oxidative stress and inflammatory response leading to CHD associated with SLE ENSG00000162692 ENSG00000163661 PMC11651451__F3 Initiation and activation of inflammasome of NLRP3, and the production process of IFN-I ENSG00000162711 ENSG00000276561 PMC6170174__F8 The role of Piezo1 and Gq/G11 proteins in endothelial response to different flow patterns ENSG00000291971 ENSG00000113448 ENSG00000103335 PMC2042025__F3 Notch pathway is a frequent target of insertion ENSG00000133961 PMC9146692__F3 Henipavirus Immune Evasion and Pathogenesis Mechanisms: Lessons Learnt from Natural Infection and Animal Models ENSG00000115415 ENSG00000164342 PMC8160512__F8 Enhanced Expression of Human Epididymis Protein 4 (HE4) Reflecting Pro-Inflammatory Status Is Regulated by CFTR in Cystic Fibrosis Bronchial Epithelial Cells ENSG00000001626 PMC4444590__F1 Mitochondrial complex I dysfunction in patients with BD could lead to increased release of superoxide anions, resulting in greater reactive oxygen species (ROS) production ENSG00000162711 ENSG00000125538 PMC4613458__F2 Signalling to eIF4E in cancer ENSG00000198793 ENSG00000164327 PMC10095454__F6 The mechanism by which SDC3 cooperates with the regulation of milk fat synthesis and inflammatory response ENSG00000162512 ENSG00000096717 ENSG00000132170 PMC11484321__F7 Distinct methylome profile of cfDNA in AMI patients reveals significant alteration in cAMP signaling pathway genes regulating cardiac muscle contraction ENSG00000041982 ENSG00000130528 ENSG00000156299 ENSG00000118729 ENSG00000149269 ENSG00000166862 ENSG00000198626 ENSG00000157445 ENSG00000121853 ENSG00000162104 PMC7796410__F2 Peptide-Based Nanomaterials for Tumor Immunotherapy ENSG00000026508 ENSG00000164949 PMC4192274__F2 Genes from the PPAR signaling pathway that were in regions surrounding QTL associated with at least one trait using the Bayesian approach ENSG00000187048 ENSG00000134824 ENSG00000162365 PMC5869700__F6 Toll-like receptor signaling pathway ENSG00000174125 ENSG00000100906 ENSG00000115415 ENSG00000187554 ENSG00000136997 ENSG00000172936 ENSG00000132478 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000143387 PMC4789659__F4 Potent and Selective CK2 Kinase Inhibitors with Effects on Wnt Pathway Signaling in Vivo ENSG00000064393 ENSG00000163349 ENSG00000127334 PMC9294428__F4 Discovering gene regulatory networks of multiple phenotypic groups using dynamic Bayesian networks ENSG00000170365 ENSG00000125740 ENSG00000100906 ENSG00000177606 ENSG00000137203 ENSG00000105810 ENSG00000132170 PMC9536840__F7 Pathway impact and pathology of example disease genome-wide association studies (GWAS) hit ENSG00000114054 ENSG00000154059 ENSG00000084774 PMC7020378__F9 Spatiotemporal metabolism in the apple fruit ENSG00000159224 PMC2743399__F3 Improved readability and performance with multi-scale information integrated in pathway visualization using metagraph ENSG00000107404 ENSG00000156076 ENSG00000005339 ENSG00000130522 ENSG00000134363 ENSG00000196782 ENSG00000155903 ENSG00000090932 ENSG00000106003 ENSG00000091073 ENSG00000100387 ENSG00000205155 ENSG00000196498 ENSG00000133961 ENSG00000114315 ENSG00000089022 ENSG00000026103 PMC2662565__F3 Bipolar disorder: from genes to behavior pathways ENSG00000168036 PMC4135953__F9 Network of genes in mice immunized with UV-V after SARS-CoV challenge ENSG00000101670 ENSG00000134339 ENSG00000185215 ENSG00000148926 ENSG00000124107 ENSG00000163661 ENSG00000276561 ENSG00000104368 ENSG00000239732 ENSG00000157227 ENSG00000263528 ENSG00000172936 ENSG00000164342 PMC9425297__F10 The role of FAM72A in SHM and CSR ENSG00000196550 ENSG00000095002 PMC11920859__F1 Gli pathway-targeted Co(iii) Schiff base complexes inhibit migration of basal cell carcinoma cells† ENSG00000128602 PMC8753429__AF1 Ginsenoside Rh2 reduces depression in offspring of mice with maternal toxoplasma infection during pregnancy by inhibiting microglial activation via the HMGB1/TLR4/NFKB signaling pathway ENSG00000189403 ENSG00000136869 PMC6955127__F6 Effects of AMI (92 mg/ml) on the mechanism of Raw264.7 cells infected with influenza virus ENSG00000183735 ENSG00000164342 PMC7934404__F2 GBPs regulate host antiviral innate immune signaling pathways ENSG00000154451 ENSG00000088888 ENSG00000162654 ENSG00000213512 ENSG00000276561 PMC9456027__F2 Factors and Pathways Modulating Endothelial Cell Senescence in Vascular Aging ENSG00000105550 ENSG00000146678 ENSG00000077463 ENSG00000096717 ENSG00000115461 PMC5041887__F6 Cell polarity signaling in the plasticity of cancer cell invasiveness ENSG00000070831 ENSG00000100592 ENSG00000134982 ENSG00000198742 ENSG00000173218 PMC5041887__F7 Cell polarity signaling in the plasticity of cancer cell invasiveness ENSG00000157827 ENSG00000070831 ENSG00000198742 PMC6372626__F6 Frequent genetic alterations in genes from angiogenesis pathway in UBC ENSG00000112414 ENSG00000142192 ENSG00000291971 ENSG00000198793 ENSG00000115904 ENSG00000197943 ENSG00000124181 ENSG00000077782 ENSG00000100485 ENSG00000168610 ENSG00000089159 PMC6856883__F3 The regulatory roles of lncRNAs in TAM by regulating classic signaling pathway ENSG00000087245 ENSG00000175104 PMC6856883__F1 Regulatory roles of lncRNAs in TAM polarization ENSG00000168610 PMC1183194__F5 Pathway-analyses based on decreased (green) and increased (red) genes detected in fibrosarcoma cells after 24 h treatment with doxorubicin ENSG00000132906 ENSG00000160789 ENSG00000142192 ENSG00000110330 ENSG00000179091 ENSG00000138794 ENSG00000196954 ENSG00000120868 ENSG00000164305 ENSG00000160049 PMC1183194__F6 Pathway-analyses based on decreased (green) and increased (red) genes detected in fibrosarcoma cells after 24 h treatment with doxorubicin ENSG00000138794 ENSG00000177606 ENSG00000065559 ENSG00000168040 ENSG00000135341 ENSG00000111348 ENSG00000139687 ENSG00000185104 ENSG00000160049 PMC1183194__F4 Pathway-analyses based on decreased (green) and increased (red) genes detected in fibrosarcoma cells after 24 h treatment with doxorubicin ENSG00000002330 ENSG00000115415 ENSG00000179091 ENSG00000120868 ENSG00000171791 ENSG00000168610 ENSG00000064012 ENSG00000164305 PMC2358953__F2 Network diagram showing the checkpoint response to uncapped telomeres ENSG00000276618 ENSG00000113456 ENSG00000172613 PMC4666900__F1 Simplified pathway diagram showing the Leishmania-APC and T cell interaction ENSG00000138378 ENSG00000291603 ENSG00000111537 ENSG00000115415 ENSG00000134982 ENSG00000198793 ENSG00000164399 ENSG00000113520 ENSG00000168610 ENSG00000113525 ENSG00000142166 PMC3064222__F9 Proposed signal transduction pathways in NG following receptor activation with leptin and CCK-8 ENSG00000163394 ENSG00000168610 ENSG00000123268 PMC7606273__F1 Autophagy and UPR pathways as well as their interconnection in SARC-CoV-2 pathogenesis ENSG00000128272 ENSG00000198793 PMC6202145__F1 Structure of hRLX2, hypothetical pathway intermediates of RXFP1/2 and the benefits of hRLX2 therapy in radiation cystitis ENSG00000133105 ENSG00000157150 ENSG00000105329 PMC521130__F2 Parallel inactivation of multiple GAL pathway genes and ecological diversification in yeasts ENSG00000063177 ENSG00000069482 PMC8941799__F1 Myocardial bioenergetics in the healthy and in the diabetic heart ENSG00000157184 ENSG00000147162 ENSG00000159399 PMC3517581__F7 Identification of Novel microRNAs in Post-Transcriptional Control of Nrf2 Expression and Redox Homeostasis in Neuronal SH-SY5Y Cells ENSG00000107105 ENSG00000116044 ENSG00000116667 ENSG00000187325 ENSG00000108960 ENSG00000105290 ENSG00000131095 ENSG00000171791 ENSG00000198300 ENSG00000204217 ENSG00000101680 ENSG00000171408 PMC9247467__F3 CD44 In Sarcomas: A Comprehensive Review and Future Perspectives ENSG00000122691 ENSG00000157227 ENSG00000026508 ENSG00000100985 ENSG00000137845 PMC9220066__F3 Therapeutic Aspects and Molecular Targets of Autophagy to Control Pancreatic Cancer Management ENSG00000177169 ENSG00000198793 ENSG00000155792 PMC6292558__F2 Bioinformatic analysis of differentially expressed proteins (DEPs) identified in this study ENSG00000172680 ENSG00000230930 ENSG00000105835 ENSG00000042832 ENSG00000058085 ENSG00000110799 ENSG00000198598 ENSG00000172037 ENSG00000053747 ENSG00000041982 ENSG00000156103 ENSG00000157150 ENSG00000130477 ENSG00000157227 ENSG00000038427 ENSG00000137674 ENSG00000220205 ENSG00000102996 ENSG00000078098 ENSG00000154096 ENSG00000133083 ENSG00000087245 ENSG00000262406 ENSG00000168818 ENSG00000189056 ENSG00000254445 ENSG00000163453 ENSG00000081052 ENSG00000110680 ENSG00000281931 ENSG00000166670 ENSG00000167346 ENSG00000164120 ENSG00000145920 ENSG00000008056 ENSG00000139219 ENSG00000133110 ENSG00000118785 ENSG00000134013 ENSG00000174059 ENSG00000128564 ENSG00000146648 ENSG00000182253 ENSG00000100234 ENSG00000135218 ENSG00000125851 ENSG00000104381 ENSG00000092820 ENSG00000171345 ENSG00000101680 ENSG00000169231 ENSG00000137801 ENSG00000136457 ENSG00000105664 ENSG00000198380 ENSG00000186340 ENSG00000149968 ENSG00000118898 ENSG00000171951 ENSG00000196604 ENSG00000089199 ENSG00000101210 ENSG00000166819 ENSG00000137673 ENSG00000157764 ENSG00000113140 ENSG00000134871 ENSG00000113296 ENSG00000291748 ENSG00000198074 ENSG00000165409 ENSG00000100985 ENSG00000181195 ENSG00000145354 PMC6151487__F5 Representative modules of ESCC-related metabolic network ENSG00000131473 ENSG00000113492 ENSG00000138029 ENSG00000120437 ENSG00000116882 ENSG00000168522 ENSG00000067064 ENSG00000100596 ENSG00000137992 ENSG00000173599 ENSG00000171759 ENSG00000105552 ENSG00000148377 ENSG00000167701 PMC8298003__F22 Skin as a critical window in unveiling the pathophysiologic principles of COVID-19 ENSG00000110799 ENSG00000130234 PMC7939748__F2 Molecular mechanisms of plant-based foods in the alleviation of NAFLD ENSG00000198793 ENSG00000142082 ENSG00000079999 ENSG00000026103 PMC11892979__F1 Clinico-genetic Analysis of Adenosine Signaling Pathway in Drug-Resistant Epilepsy ENSG00000156110 ENSG00000197381 PMC7939748__F3 Molecular mechanisms of plant-based foods in the alleviation of AFLD ENSG00000150907 ENSG00000130649 ENSG00000172936 ENSG00000136869 ENSG00000164305 ENSG00000079999 ENSG00000026103 PMC7245796__F4 Metabolites on post-translational modification of EZH2 protein ENSG00000131473 ENSG00000147162 ENSG00000013375 PMC5206726__F1 Relaxation oscillations and hierarchy of feedbacks in MAPK signaling ENSG00000186575 ENSG00000146648 ENSG00000196712 PMC4023047__F3 Role of POR in biosynthesis of androgens in classic and alternate pathways ENSG00000151632 ENSG00000277893 ENSG00000161513 ENSG00000203859 ENSG00000137714 ENSG00000127948 PMC5431431__F2 DNA methylation and Transcriptome Changes Associated with Cisplatin Resistance in Ovarian Cancer ENSG00000175206 ENSG00000105329 ENSG00000138798 ENSG00000120149 ENSG00000168036 ENSG00000135111 ENSG00000118971 ENSG00000171345 ENSG00000136826 ENSG00000101680 ENSG00000104368 ENSG00000109819 ENSG00000041982 ENSG00000143320 ENSG00000113558 ENSG00000128052 ENSG00000136997 ENSG00000169429 ENSG00000177508 ENSG00000118898 ENSG00000164619 ENSG00000033867 ENSG00000064195 ENSG00000113196 ENSG00000142627 ENSG00000285109 ENSG00000197616 ENSG00000135480 ENSG00000132170 ENSG00000164736 ENSG00000177606 ENSG00000075891 ENSG00000196208 PMC5336163__F8 PAF-mediated endotoxin tolerance ENSG00000136011 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC7985098__F4 Effects of statin on NLRP3 inflammasome and TLRs pathways ENSG00000162711 ENSG00000173992 ENSG00000172936 PMC3159112__F5 Ad signaling in endothelial cells ENSG00000159346 ENSG00000285070 PMC6863963__F1 Conflicting roles of RASAL2 in different cancers ENSG00000198793 ENSG00000026508 ENSG00000168036 ENSG00000112715 PMC5743757__F1 Oxidative stress and cellular pathways of asthma and inflammation: Therapeutic strategies and pharmacological targets ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000136869 ENSG00000150455 ENSG00000164342 PMC5743757__F2 Oxidative stress and cellular pathways of asthma and inflammation: Therapeutic strategies and pharmacological targets ENSG00000150455 ENSG00000168610 ENSG00000132341 PMC7985098__F1 Roles of NLRPs and TLRs pathways in atherosclerosis pathophysiology ENSG00000162711 ENSG00000173992 ENSG00000172936 PMC6997467__F1 Signaling pathway of ncRNAs in RA ENSG00000174125 ENSG00000168036 ENSG00000172936 ENSG00000130159 ENSG00000175104 PMC8225153__F4 Black Cumin (Nigella sativa L.): A Comprehensive Review on Phytochemistry, Health Benefits, Molecular Pharmacology, and Safety ENSG00000134057 ENSG00000198793 ENSG00000168036 ENSG00000123374 ENSG00000168610 PMC8225153__F3 Black Cumin (Nigella sativa L.): A Comprehensive Review on Phytochemistry, Health Benefits, Molecular Pharmacology, and Safety ENSG00000142192 ENSG00000087085 ENSG00000119912 PMC5679744__F7 Fgf10-Hippo epithelial mesenchymal crosstalk maintains and recruits lung basal stem cells ENSG00000070193 ENSG00000188064 PMC8446765__F1 Dysregulated androgen synthesis and anti-androgen resistance in advanced prostate cancer PMC5447318__F2 Infection of virus can stimulate airway epithelium and produce antimicrobiota defense through IL-22/IL-22R signaling pathway ENSG00000239732 ENSG00000163220 ENSG00000136869 ENSG00000164342 PMC4155893__F3 Positive feedback loop between EGFR and ERA36.Notes: A positive feedback loop has been confirmed that EGFR signaling activates transcription of ERA36 through an AP-1-binding site in the promoter region of ERA36 ENSG00000291971 ENSG00000146648 PMC7907040__F2 Major signaling pathways of GPCR subfamilies ENSG00000096088 ENSG00000168036 PMC4562327__F1 Transition of primordial to primary follicles ENSG00000162552 ENSG00000104899 ENSG00000186766 ENSG00000164404 ENSG00000130385 ENSG00000133116 PMC4064064__F3 MicroRNAs and Toll-like receptor signaling pathway in hepatitis B virus infection ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC8395432__F2 SARS-CoV-2: Understanding the Transcriptional Regulation of ACE2 and TMPRSS2 and the Role of Single Nucleotide Polymorphism (SNP) at Codon 72 of p53 in the Innate Immune Response against Virus Infection ENSG00000143799 ENSG00000104237 ENSG00000184012 PMC6528338__F5 An integrated gene interaction network built for genes related to wing dimorphism ENSG00000131469 ENSG00000156482 ENSG00000136942 ENSG00000111641 ENSG00000108107 ENSG00000130810 ENSG00000174444 ENSG00000137877 ENSG00000146066 ENSG00000161016 ENSG00000108592 ENSG00000063177 ENSG00000140455 ENSG00000149100 ENSG00000105447 ENSG00000122965 ENSG00000189067 ENSG00000280548 PMC8395432__F6 SARS-CoV-2: Understanding the Transcriptional Regulation of ACE2 and TMPRSS2 and the Role of Single Nucleotide Polymorphism (SNP) at Codon 72 of p53 in the Innate Immune Response against Virus Infection ENSG00000143799 ENSG00000239732 ENSG00000130234 ENSG00000184012 ENSG00000136869 ENSG00000164342 PMC6442574__F1 Focal forebrain IR/IGF1R DKO eliminates signaling by receptor homodimers and hybrids in hippocampus or central amygdala ENSG00000169047 ENSG00000198793 ENSG00000140443 PMC8205700__F4 Mesenchymal stem cell-derived exosomes: a promising vector in treatment for diabetes and its microvascular complications ENSG00000169554 ENSG00000198793 ENSG00000136869 ENSG00000112715 PMC8035080__F4 Mycolic acid biosynthesis and recycling ENSG00000123999 ENSG00000100473 PMC9330582__F1 Effect of the Gut Microbiota on Systemic and Anti-Tumor Immunity and Response to Systemic Therapy against Cancer ENSG00000181847 ENSG00000198793 ENSG00000154059 ENSG00000049768 ENSG00000168610 PMC9659945__F1 Progress of protein synthesis factors eIFs, eEFs and eRFs in inflammatory bowel disease and colorectal cancer pathogenesis ENSG00000128272 ENSG00000172201 PMC9659945__F2 Progress of protein synthesis factors eIFs, eEFs and eRFs in inflammatory bowel disease and colorectal cancer pathogenesis ENSG00000198793 ENSG00000136997 ENSG00000167658 PMC5976976__F4 Hypothetical diagram showing target sites for the action of curcumin (diferuloylmethane) in signal transduction pathway ENSG00000142192 ENSG00000181019 ENSG00000178573 ENSG00000171791 ENSG00000079999 PMC7594717__F8 Metabolic flux map for C ENSG00000122966 ENSG00000172005 PMC10450211__F2 Circular RNAs: novel actors of Wnt signaling pathway in lung cancer progression ENSG00000078747 ENSG00000168036 PMC10509026__F1 Schematic view of vitamin D (VD) signaling pathway mediated VD receptor (VDR) ENSG00000111012 ENSG00000118972 ENSG00000152266 ENSG00000019186 ENSG00000186104 PMC9996228__F2 Genetic control of meiosis surveillance mechanisms in mammals ENSG00000149311 ENSG00000175054 ENSG00000178222 ENSG00000054796 PMC10450211__F1 An Illustration of the circRNAs that directly or through specific miRNA sponges activate the Wnt signaling pathway and play a role in the progression of lung cancer ENSG00000196418 ENSG00000102349 ENSG00000174804 ENSG00000140285 ENSG00000104967 ENSG00000124766 ENSG00000126003 ENSG00000115760 PMC6854078__F8 Proposed schematic representation of the signaling pathways involved in the redox regulation of inflammasome activation in G6PD-deficient cells ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC9581482__F8 Proposed model of LXR inhibition by oxysterol misbalance contributes to inflammation and fibrosis in murine WD ENSG00000042832 ENSG00000123191 ENSG00000169710 PMC9252087__F2 PCycDB: a comprehensive and accurate database for fast analysis of phosphorus cycling genes ENSG00000161634 ENSG00000128951 ENSG00000156110 ENSG00000153574 ENSG00000150787 ENSG00000185129 ENSG00000146676 PMC4974116__F3 HCV dynamics and cellular gene expression in uPA-SCID chimeric mice with humanized livers during intravenous silibinin monotherapy ENSG00000169908 ENSG00000148346 ENSG00000105327 ENSG00000117228 ENSG00000169242 ENSG00000166401 ENSG00000169245 ENSG00000125398 ENSG00000092621 ENSG00000188021 ENSG00000138755 ENSG00000163131 ENSG00000171848 ENSG00000169429 ENSG00000115009 PMC11652361__F1 Siglec-15 affects four key areas: bone metabolism, modulates infections caused by pathogenic microorganisms, immune regulation, and the pathogenesis of hematologic diseases ENSG00000125538 ENSG00000121058 ENSG00000026508 ENSG00000175104 PMC9273851__F2 Ferroptosis and Emerging Links to the Pathology of Neurodegenerative Diseases ENSG00000228716 ENSG00000151012 ENSG00000167468 ENSG00000072274 ENSG00000197429 ENSG00000102967 ENSG00000079999 PMC11652361__F2 Illustration of osteoclasts differentiation ENSG00000026508 ENSG00000175104 PMC9626029__F4 Bleeding Propensity in Waldenström Macroglobulinemia: Potential Causes and Evaluation ENSG00000226275 ENSG00000110799 ENSG00000137845 PMC7653364__F4 Dysregulation of A-to-I RNA editing promotes cancer progression ENSG00000228716 ENSG00000011677 ENSG00000163453 PMC6994382__F2 Gene-network for genes mapped to 16 variants which replicated in both Hispanics and African Americans ENSG00000134460 ENSG00000140968 ENSG00000163599 ENSG00000203710 ENSG00000000971 ENSG00000170348 ENSG00000168811 ENSG00000184840 ENSG00000116815 ENSG00000175416 ENSG00000182108 ENSG00000070371 ENSG00000038532 ENSG00000164136 ENSG00000117335 PMC9626029__F3 Bleeding Propensity in Waldenström Macroglobulinemia: Potential Causes and Evaluation ENSG00000197943 ENSG00000010671 PMC4976849__F1 Folate metabolic pathway single nucleotide polymorphisms: a predictive pharmacogenetic marker of methotrexate response in Indian (Asian) patients with rheumatoid arthritis ENSG00000228716 ENSG00000100714 ENSG00000136877 ENSG00000196839 ENSG00000103222 ENSG00000124275 ENSG00000035928 ENSG00000137563 ENSG00000023839 PMC7160326__F1 Different WNT signaling pathways ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000100592 ENSG00000134982 ENSG00000168036 ENSG00000146122 PMC7160326__F2 The proteins that underlie Robinow syndrome or omodysplasia (indicated in red) in the WNT/planar cell polarity (PCP) pathway ENSG00000107404 ENSG00000167693 ENSG00000169071 ENSG00000100592 ENSG00000169750 ENSG00000183098 ENSG00000146122 ENSG00000076716 ENSG00000161202 PMC7160326__F3 Modulators of the canonical WNT signaling pathway that are involved in the regulation of bone mass in human disease ENSG00000107404 ENSG00000281324 ENSG00000162337 ENSG00000134569 ENSG00000134982 ENSG00000168036 ENSG00000125084 PMC1899878__F1 Regulation of dimorphism in C ENSG00000196511 ENSG00000117298 PMC7269828__F1 Predictive biomarkers for PARPi efficacy ENSG00000167258 ENSG00000149311 ENSG00000083093 ENSG00000182185 ENSG00000187741 ENSG00000139618 ENSG00000183765 PMC5328506__F2 Programmed cell death as a defence against infection ENSG00000124256 ENSG00000137275 ENSG00000172936 ENSG00000136869 ENSG00000168040 ENSG00000168404 ENSG00000285379 ENSG00000164342 PMC5328506__F4 Programmed cell death as a defence against infection ENSG00000162711 ENSG00000111537 ENSG00000137275 ENSG00000125538 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC4114189__F1 Molecular pathway of the mechano-induction of tenascin-C ENSG00000163914 ENSG00000172005 PMC4981669__F5 Possible mechanism for the antagonistic effect of Lpp and RNA in innate immune stimulation in monocytes and macrophages ENSG00000174125 ENSG00000150782 ENSG00000172936 PMC7110195__F1 Nucleic acid sensors inducing type I and type III interferons ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000167207 ENSG00000174953 ENSG00000172936 PMC4981669__F4 Possible mechanisms for the synergistic immune stimulation of TLR2 and NOD2 ligands ENSG00000174125 ENSG00000172936 PMC9261320__F1 Endoplasmic Reticulum Stress and miRNA Impairment in Aging and Age-Related Diseases ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC2783518__F1 Wnt signaling and senescence: a tug of war in early neoplasia? ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC9261320__F2 Endoplasmic Reticulum Stress and miRNA Impairment in Aging and Age-Related Diseases ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC2692400__F1 Hormone and nutrient signaling pathways modulating leptin translation ENSG00000163435 ENSG00000042832 ENSG00000169047 PMC5614756__F1 DJ-1 activates ERK1/2 signaling pathway PMC6154041__F3 The role of Wnt5a-Ror2 signaling in osteoclast differentiation ENSG00000169071 ENSG00000163914 ENSG00000177606 ENSG00000185591 ENSG00000160447 PMC9207338__F1 Pathophysiological Role of Nucleic Acid-Sensing Pattern Recognition Receptors in Inflammatory Diseases ENSG00000162711 ENSG00000163568 ENSG00000163565 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000125538 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC5533708__F6 TANC protein interaction network ENSG00000170921 ENSG00000154310 ENSG00000150457 PMC7348178__F6 VEGI‐251‐induced TAM apoptosis ENSG00000102871 ENSG00000127191 PMC6397982__F8 HMG-CoA Reductase Inhibitors Attenuate Neuronal Damage by Suppressing Oxygen Glucose Deprivation-Induced Activated Microglial Cells ENSG00000130164 PMC10977553__F6 Mechanism through which agarwood against RAS ENSG00000171855 ENSG00000156735 ENSG00000110330 ENSG00000167207 ENSG00000165197 ENSG00000102871 ENSG00000163739 ENSG00000124875 ENSG00000121879 ENSG00000164305 ENSG00000172216 ENSG00000157227 ENSG00000149968 ENSG00000078747 ENSG00000125538 ENSG00000056558 ENSG00000164400 ENSG00000128342 ENSG00000168404 ENSG00000064012 ENSG00000026103 ENSG00000104365 ENSG00000100906 ENSG00000137275 ENSG00000173039 ENSG00000007908 ENSG00000213341 ENSG00000168040 ENSG00000125347 ENSG00000127191 ENSG00000073756 ENSG00000108691 ENSG00000128272 ENSG00000118503 ENSG00000177606 ENSG00000136848 ENSG00000184371 ENSG00000131323 ENSG00000100985 ENSG00000083799 ENSG00000162692 ENSG00000285379 ENSG00000115009 PMC6834162__F2 Methotrexate (MTX) transporters, metabolic pathways and intracellular enzyme targets ENSG00000228716 ENSG00000136877 ENSG00000035928 ENSG00000137563 PMC3857329__F3 As discussed in the preceding sections, the catalytic activation method using HNTf2 allows efficient borylation with optimal substrates such as 22 PMC6834162__F4 MTX affects several signal transduction pathways implicated in the pathogenesis of rheumatoid arthritis (RA) ENSG00000111537 ENSG00000125538 ENSG00000164136 PMC10560454__F1 tFNAs improve hUMSC chondrogenic potential through the regulation of the PI3K/AKT pathway ENSG00000139219 ENSG00000125398 ENSG00000157766 ENSG00000198793 PMC8586713__F1 PTSD as an Endothelial Disease: Insights From COVID-19 ENSG00000141867 ENSG00000140564 ENSG00000130234 ENSG00000122194 PMC10508518__F5 KEGG simulated signaling pathway analysis ENSG00000132906 ENSG00000291355 ENSG00000110395 ENSG00000213658 ENSG00000134982 ENSG00000111837 ENSG00000172005 ENSG00000122008 ENSG00000047597 PMC3545297__F1 Energy metabolism in a typical mammalian cell ENSG00000069482 ENSG00000026103 PMC6784888__F4 Leveraging single-cell genomics to expand the fungal tree of life ENSG00000173599 PMC8880811__F3 The Metabolome and Non-Coding RNA on Pheochromocytomas and Paragangliomas: An Update ENSG00000198793 ENSG00000196712 PMC3890531__F4 IGF signaling pathway ENSG00000030582 ENSG00000002330 ENSG00000168610 ENSG00000140443 PMC6826966__F2 Mechanism of resistance to arsenic trioxide- all-trans retinoic acid (ATO-ATRA) therapy in APL ENSG00000180210 ENSG00000122025 ENSG00000183337 ENSG00000198793 ENSG00000109906 ENSG00000140464 PMC9097844__F8 ASIC1a stimulates the resistance of human hepatocellular carcinoma by promoting EMT via the AKT/GSK3B/Snail pathway driven by TGFB/Smad signals ENSG00000087245 ENSG00000100985 PMC5110973__F4 Nitrogen-induced metabolic changes and molecular determinants of carbon allocation in Dunaliella tertiolecta ENSG00000159224 ENSG00000196549 ENSG00000172005 ENSG00000198670 ENSG00000102977 PMC9593054__F2 NLRP3-mediated pyroptosis in diabetic nephropathy ENSG00000278718 ENSG00000162711 ENSG00000198793 ENSG00000136869 ENSG00000096717 ENSG00000089163 PMC8774030__F1 Therapeutic Potential of Naturally Occurring Small Molecules to Target the Wnt/Beta-Catenin Signaling Pathway in Colorectal Cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000133067 ENSG00000183691 ENSG00000185269 ENSG00000173273 PMC6423768__F7 A schematic diagram of exosomal miR-128-3p based signaling pathway in CRC treatment ENSG00000168283 ENSG00000122691 PMC3931461__F1 Progress in molecular-based management of differentiated thyroid cancer ENSG00000157764 ENSG00000198793 PMC3506908__F4 Pathway analysis derived by comparison of the relative abundance of metabolites from sera derived from patients with locoregional CRC and liver-only metastases, as determined by GC-MS ENSG00000179914 ENSG00000141639 ENSG00000160181 ENSG00000274205 ENSG00000197372 ENSG00000118508 ENSG00000161921 ENSG00000127743 ENSG00000135960 ENSG00000171435 ENSG00000162545 ENSG00000132514 ENSG00000106624 ENSG00000118094 ENSG00000152377 ENSG00000147588 ENSG00000171119 ENSG00000123689 ENSG00000101425 PMC3943494__F3 Ceramide Metabolic Pathway in Epidermis ENSG00000100422 ENSG00000102172 ENSG00000143418 PMC7503488__F1 Actions of metformin on immune cells, blood platelets and endothelium during the development of neurodegeneration disease: Metformin has multiple properties such as anti-inflammatory, antioxidant and antithrombotic properties ENSG00000110799 ENSG00000163737 PMC9252100__F6 Curcumenol Mitigates the Inflammation and Ameliorates the Catabolism Status of the Intervertebral Discs In Vivo and In Vitro via Inhibiting the TNFA/NFKB Pathway ENSG00000115602 ENSG00000131323 PMC3848109__F3 TGF-ß fibrotic pathway ENSG00000122194 PMC9593054__F3 NLRP3-mediated pyroptosis in diabetic nephropathy ENSG00000278718 ENSG00000162711 ENSG00000150907 ENSG00000198793 ENSG00000265972 PMC3011942__F1 Phosphatidylinositol 3-kinase-Akt (PI3K-Akt) pathway becomes activated via stimulation of receptor tyrosine kinases (RTKs) and the assembly of receptor–PI3K complexes ENSG00000002330 ENSG00000070831 ENSG00000005882 ENSG00000198793 PMC9593054__F4 NLRP3-mediated pyroptosis in diabetic nephropathy ENSG00000278718 ENSG00000162711 ENSG00000066044 ENSG00000079999 PMC5592666__F2 CoQ6biosynthetic pathway in S ENSG00000132423 ENSG00000119723 ENSG00000173085 ENSG00000167186 PMC9593054__F5 NLRP3-mediated pyroptosis in diabetic nephropathy ENSG00000162711 ENSG00000198793 PMC9593054__F6 NLRP3-mediated pyroptosis in diabetic nephropathy ENSG00000278718 ENSG00000162711 ENSG00000198793 ENSG00000096717 ENSG00000215301 ENSG00000165819 PMC3112527__F3 Summary of the signaling pathway mediated by RET ENSG00000291971 ENSG00000106070 ENSG00000125170 ENSG00000101134 ENSG00000292254 PMC9550454__F6 Protective Mechanisms of Nootropic Herb Shankhpushpi (Convolvulus pluricaulis) against Dementia: Network Pharmacology and Computational Approach ENSG00000177455 ENSG00000186716 ENSG00000136997 PMC9550454__F7 Protective Mechanisms of Nootropic Herb Shankhpushpi (Convolvulus pluricaulis) against Dementia: Network Pharmacology and Computational Approach ENSG00000142192 ENSG00000002330 ENSG00000148572 ENSG00000166278 ENSG00000168040 ENSG00000181195 PMC10622993__F2 Common signaling pathways and ALDH1 expression in CCA ENSG00000162337 ENSG00000134982 ENSG00000170558 ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC3279640__F1 Bi-potential gonad development to either testis or ovary ENSG00000162552 ENSG00000169218 ENSG00000104899 ENSG00000143355 ENSG00000285109 ENSG00000134363 ENSG00000168036 ENSG00000102678 ENSG00000173894 ENSG00000170370 ENSG00000125398 ENSG00000137090 ENSG00000005513 ENSG00000139549 ENSG00000077782 PMC2586270__F6 Furin action in pituitary gonadotrope cells ENSG00000140564 PMC3279640__F2 Known genes and pathways of the different cell types of the developing testis in mouse (modified from Wainwright and Wilhelm ) ENSG00000162552 ENSG00000104899 ENSG00000285109 ENSG00000248099 ENSG00000102678 ENSG00000100146 ENSG00000066468 ENSG00000125398 ENSG00000168066 ENSG00000005513 ENSG00000074181 ENSG00000203859 ENSG00000139549 ENSG00000114315 ENSG00000054803 ENSG00000112299 PMC4772163__F5 Gene dysregulation is restored in the Parkinson’s disease MPTP neurotoxic mice model upon treatment of the therapeutic drug CuII(atsm) ENSG00000081189 ENSG00000292254 PMC3170587__F2 Microenvironmental genomic alterations reveal signaling networks for head and neck squamous cell carcinoma ENSG00000291971 ENSG00000142273 ENSG00000095794 PMC4330468__F1 Molecular targets and associated therapies to block three immunosuppressive checkpoints in a malignant brain tumor (glioma) model ENSG00000134982 ENSG00000163599 PMC11740643__F5 Treatment of gouty lumbar spinal stenosis: a case report and bioinformatics analysis ENSG00000142192 ENSG00000111537 ENSG00000179091 ENSG00000123374 ENSG00000146648 ENSG00000109787 ENSG00000143387 PMC8187562__F13 Pre-clinical Evidence: Berberine as a Promising Cardioprotective Candidate for Myocardial Ischemia/Reperfusion Injury, a Systematic Review, and Meta-Analysis ENSG00000148400 ENSG00000150907 ENSG00000198793 ENSG00000171791 ENSG00000096717 ENSG00000114315 ENSG00000168610 PMC6822710__F1 Mck1 kinase is a new player in the DNA damage checkpoint pathway ENSG00000094804 PMC8512456__F2 Tumor immune microenvironment in epidermal growth factor receptor-mutated non-small cell lung cancer before and after epidermal growth factor receptor tyrosine kinase inhibitor treatment: a narrative review ENSG00000167601 ENSG00000081041 ENSG00000118785 ENSG00000163739 ENSG00000163599 ENSG00000124875 ENSG00000049768 ENSG00000168610 ENSG00000146648 ENSG00000121966 ENSG00000140443 ENSG00000163481 PMC6255705__F9 Schematic representation of metabolic reprogramming caused by the DAPAT mutation during diurnal cycle ENSG00000180902 ENSG00000062485 PMC10551637__F1 Targets and applications of nanodrug targeting myeloid cells in osteosarcoma for the enhancement of immunotherapy ENSG00000198053 ENSG00000214285 PMC7301642__F5 ATG8-mediated selective autophagy pathways in plants ENSG00000188554 ENSG00000229314 PMC8024584__F8 MAPK-signaling pathway with 5 selected genes (Ssk1, Pbs2, Ste11, Hog1, and Ssk2), known to be associated with response to osmotic stress ENSG00000110395 ENSG00000188404 PMC4709637__F1 Exogenous avian leukosis virus-induced activation of the ERK/AP1 pathway is required for virus replication and correlates with virus-induced tumorigenesis ENSG00000104626 ENSG00000087095 ENSG00000170458 ENSG00000177606 ENSG00000130159 ENSG00000175104 ENSG00000127191 ENSG00000026103 PMC3227962__F5 Targets for intervention in the TGFB1 pathway (partial list) [, , ] ENSG00000198793 ENSG00000163914 ENSG00000067900 PMC7559222__F7 SNORA71A/mRNA/pathway interaction network constructed and visualized by Cytoscape software ENSG00000164587 ENSG00000158578 ENSG00000077312 ENSG00000166947 ENSG00000170262 ENSG00000137563 ENSG00000000005 PMC10607711__F2 Propagation of pressure in the epidermis and certain mechanotransducers involving the modulation of mechanical stimuli in keratinocytes ENSG00000036828 ENSG00000103335 PMC2875073__F5 Albumin alters TGFB pathway gene expression ENSG00000049323 ENSG00000137834 ENSG00000138795 ENSG00000157933 ENSG00000005339 ENSG00000109320 ENSG00000050748 ENSG00000138798 ENSG00000183691 ENSG00000134363 ENSG00000020633 ENSG00000168610 ENSG00000125084 ENSG00000137801 ENSG00000170365 ENSG00000111537 ENSG00000118785 ENSG00000095739 ENSG00000115415 ENSG00000177606 ENSG00000128342 PMC3741150__F8 Mitochondrial Transcription Factor A, an Endogenous Danger Signal, Promotes TNFA Release via RAGE- and TLR9-Responsive Plasmacytoid Dendritic Cells ENSG00000239732 ENSG00000117298 PMC7762580__F1 Fructose and glucose degradation pathways ENSG00000140263 ENSG00000085662 ENSG00000136872 PMC2386920__F7 IRF-5 in the innate antiviral response ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000107201 ENSG00000175104 ENSG00000184216 PMC7762580__F2 Fructose contribution to the pentose phosphate pathway ENSG00000197713 ENSG00000140263 ENSG00000138030 ENSG00000085662 ENSG00000136872 PMC7708042__F4 DNA breakage formation induced by G4 stabilization ENSG00000138346 ENSG00000138385 PMC4390799__F1 For therapeutic modulation of the UPR ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8904388__F1 Multifaceted Roles of cAMP Signaling in the Repair Process of Spinal Cord Injury and Related Combination Treatments ENSG00000163914 ENSG00000124107 ENSG00000118520 PMC7699867__F2 Regulation between actin cytoskeleton and Yap/Yorkie at the apical cell cortex in Drosophila and in mammalian cells ENSG00000038382 PMC11575037__F3 Figure shows selected subnetworks of the differential network for Liver tissue in Diabetes ENSG00000223573 ENSG00000168329 ENSG00000162772 ENSG00000121807 ENSG00000069667 ENSG00000115138 ENSG00000169174 ENSG00000104899 ENSG00000197635 ENSG00000103569 ENSG00000281879 ENSG00000169752 ENSG00000132170 ENSG00000111012 ENSG00000138378 ENSG00000285379 ENSG00000115009 ENSG00000131400 ENSG00000112799 ENSG00000019991 ENSG00000162711 ENSG00000139572 ENSG00000115137 ENSG00000196932 ENSG00000135439 ENSG00000164251 ENSG00000163568 ENSG00000130649 ENSG00000189430 ENSG00000142082 ENSG00000174807 ENSG00000128165 ENSG00000127954 ENSG00000129214 ENSG00000196549 ENSG00000130234 ENSG00000118520 ENSG00000112486 ENSG00000148346 ENSG00000099985 ENSG00000196839 ENSG00000198851 ENSG00000135253 ENSG00000277943 ENSG00000184979 ENSG00000153208 ENSG00000111537 ENSG00000101255 ENSG00000067606 ENSG00000126353 ENSG00000005381 ENSG00000073861 PMC5215839__F2 Posttranscriptional mechanisms of regulation of the miRNA biogenesis pathway ENSG00000134744 ENSG00000128191 ENSG00000113360 PMC11575037__F5 Figure shows Selected subnetwork of the differential network for Aorta tissue in Diabetes ENSG00000115226 ENSG00000223573 ENSG00000274211 ENSG00000081181 ENSG00000168329 ENSG00000169047 ENSG00000150455 ENSG00000121807 ENSG00000069667 ENSG00000239732 ENSG00000106070 ENSG00000160703 ENSG00000115138 ENSG00000177674 ENSG00000168404 ENSG00000104899 ENSG00000204103 ENSG00000197635 ENSG00000281879 ENSG00000091879 ENSG00000125347 ENSG00000169752 ENSG00000138378 ENSG00000161634 ENSG00000197296 ENSG00000079435 ENSG00000096717 ENSG00000285379 ENSG00000146648 ENSG00000131400 ENSG00000073737 ENSG00000112799 ENSG00000019991 ENSG00000162711 ENSG00000196932 ENSG00000081721 ENSG00000163291 ENSG00000135439 ENSG00000138798 ENSG00000130649 ENSG00000128165 ENSG00000130164 ENSG00000196549 ENSG00000130234 ENSG00000197594 ENSG00000137265 ENSG00000056558 ENSG00000118520 ENSG00000090376 ENSG00000164342 ENSG00000026103 ENSG00000148346 ENSG00000099985 ENSG00000196839 ENSG00000198851 ENSG00000086991 ENSG00000135253 ENSG00000277943 ENSG00000184979 ENSG00000149311 ENSG00000157368 ENSG00000153208 ENSG00000101255 ENSG00000067606 ENSG00000126353 ENSG00000005381 ENSG00000073861 PMC7803379__F1 Non-redox cycling mechanisms of oxidative stress induced by PM metals ENSG00000146648 ENSG00000105227 ENSG00000079999 PMC8558403__F2 Gut Microbiota for Esophageal Cancer: Role in Carcinogenesis and Clinical Implications ENSG00000108691 ENSG00000136869 ENSG00000277943 PMC3433910__F1 Putative scheme of the cellular metabolism in the hydrogen producing arachaeon T ENSG00000110711 ENSG00000173599 ENSG00000198931 ENSG00000184207 PMC11575037__F7 Figure shows selected subnetwork of the differential network for Heart tissue in Diabetes ENSG00000149311 ENSG00000108691 ENSG00000196839 ENSG00000148926 ENSG00000079435 ENSG00000131400 ENSG00000122678 ENSG00000163631 PMC9564177__F1 KEAP1-NRF2 System and Esophageal Cancer ENSG00000181019 ENSG00000079999 PMC1288546__F1 Human SHH-PTCH-GLI pathway (left) and its links to human diseases (right) ENSG00000106571 PMC4156318__F2 ATM-NFKB-regulated signaling network causing the adaptive resistance to IR in normal human skin epithelial HK18 cells ENSG00000149311 ENSG00000134057 PMC7387173__F3 Segregation of acute activity and cell transcriptional gene expression in POMC and NPY/AgRP cells ENSG00000171105 ENSG00000173599 ENSG00000115138 ENSG00000121853 ENSG00000072315 PMC4837871__F2 Sex-determining Region of Y Chromosome-related High-mobility-group Box 2 in Malignant Tumors: Current Opinions and Anticancer Therapy ENSG00000138798 ENSG00000168036 ENSG00000128602 ENSG00000118777 ENSG00000168610 ENSG00000146648 PMC12155444__F6 Composite Enzyme-Gene Network of Key Metabolites and Targets ENSG00000109814 ENSG00000129219 ENSG00000283887 ENSG00000136267 ENSG00000276559 ENSG00000196839 ENSG00000077044 ENSG00000173039 ENSG00000149091 ENSG00000058866 ENSG00000002549 PMC9043895__F3 Corrigendum: The Role of Histone Lysine Methylation in the Response of Mammalian Cells to Ionizing Radiation ENSG00000185513 ENSG00000151376 ENSG00000083093 ENSG00000173120 ENSG00000011258 ENSG00000196591 ENSG00000066135 ENSG00000165280 ENSG00000112130 ENSG00000012048 ENSG00000198901 ENSG00000065833 ENSG00000163961 ENSG00000051180 ENSG00000082212 PMC9569498__F1 O-GlcNAcylation in Renal (Patho)Physiology ENSG00000147162 ENSG00000198408 ENSG00000013375 PMC3607541__F6 Interleukin-1 alpha modulates neutrophil recruitment in chronic inflammation induced by hydrocarbon oil ENSG00000108691 ENSG00000108688 ENSG00000172936 ENSG00000121807 ENSG00000276561 PMC9310808__F1 Chemical Synthesis of the Fluorescent, Cyclic Dinucleotides cthGAMP ENSG00000183735 ENSG00000164430 ENSG00000148798 PMC5609887__F5 Integrated analysis profiles of long non-coding RNAs reveal potential biomarkers of drug resistance in lung cancer ENSG00000164932 ENSG00000132031 ENSG00000113070 ENSG00000139269 ENSG00000175352 ENSG00000139926 ENSG00000196739 ENSG00000008083 ENSG00000114738 ENSG00000136603 ENSG00000011422 ENSG00000019549 ENSG00000108821 ENSG00000139278 ENSG00000204217 PMC6072829__F7 Zyflamend and NFKB pathway ENSG00000087245 ENSG00000150991 ENSG00000100985 PMC4263263__F2 Metacore analysis of leading edge genes ENSG00000145604 ENSG00000134982 ENSG00000166851 ENSG00000117399 PMC4586784__F2 Modes of signaling in Hh pathway-dependent cancer ENSG00000164161 ENSG00000128602 PMC4263263__F3 Metacore analysis of leading edge genes ENSG00000187682 ENSG00000128272 ENSG00000177606 ENSG00000100219 ENSG00000127191 PMC9603940__F6 Microbe-Derived Antioxidants Reduce Lipopolysaccharide-Induced Inflammatory Responses by Activating the Nrf2 Pathway to Inhibit the ROS/NLRP3/IL-1B Signaling Pathway ENSG00000162711 ENSG00000175793 ENSG00000125538 PMC7662987__F5 Schematic display of antitumor activity of CUDC-907 hybrid drug against prostate cancer cells ENSG00000167325 ENSG00000136997 ENSG00000171848 PMC11602063__F15 ROS promote ginsenoside biosynthesis under water stress ENSG00000197429 ENSG00000113161 PMC5466420__F10 Illustration depicting the roles of Yap in submandibular gland epithelial development ENSG00000186847 ENSG00000124882 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC8875669__F2 Biosynthesis and the Roles of Plant Sterols in Development and Stress Responses ENSG00000090402 ENSG00000116133 ENSG00000197429 ENSG00000128602 ENSG00000163479 PMC9028838__F1 MicroRNAs: Novel Targets in Hepatic Ischemia–Reperfusion Injury ENSG00000125686 ENSG00000096717 ENSG00000142082 ENSG00000175104 ENSG00000121966 PMC8238121__F1 PARP Inhibitors in the Ovarian Cancer Microenvironment: Moving Forward From Synthetic Lethality ENSG00000169245 ENSG00000183735 ENSG00000164430 ENSG00000051180 PMC8050411__F5 Enriched canonical pathways of the DEGs associated with the p53 signalling pathway identified by IPA, showing gene expression and predicted relationships between top regulated 311 nm UVB DEGs at 6 h and 18 h post-irradiation ENSG00000149311 ENSG00000175054 ENSG00000135473 ENSG00000132646 ENSG00000177606 ENSG00000078237 ENSG00000140464 PMC11938626__F6 Oncogenic mechanisms of HBsAg mutants in hepatocarcinogenesis ENSG00000107338 ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000112715 PMC8050411__F6 Enriched canonical pathway of IFN transcriptomic pathway identified by IPA, showing gene expression and predicted relationships between molecules differentially regulated by 311 nm UVB 18 h after irradiation ENSG00000213928 ENSG00000111537 ENSG00000089127 ENSG00000185201 ENSG00000157601 ENSG00000125347 ENSG00000230034 PMC11938626__F2 HBsAg induces the HCC tumorigenesis by promoting proliferation ENSG00000291971 ENSG00000134982 ENSG00000168036 PMC11938626__F3 Various oncogenic effects induced by the ER stress in the development and progression of HBV-related HCC ENSG00000131473 ENSG00000107338 ENSG00000128272 ENSG00000134824 ENSG00000198793 ENSG00000100219 ENSG00000112715 ENSG00000127191 ENSG00000168610 ENSG00000123983 PMC4392845__F1 13C Isotope-Assisted Methods for Quantifying Glutamine Metabolism in Cancer Cells ENSG00000105953 ENSG00000115419 ENSG00000062485 PMC4904011__F1 Protein pathway driving the migraine process at the tripartite synapse ENSG00000148219 ENSG00000167371 ENSG00000291761 ENSG00000112214 ENSG00000132639 PMC3553975__F8 Subnetworks identified from (a) Loi et al ENSG00000159216 ENSG00000173757 ENSG00000106070 ENSG00000177606 ENSG00000139372 ENSG00000196498 ENSG00000067334 ENSG00000124356 ENSG00000008735 ENSG00000132170 PMC3553975__F6 Subnetworks identified from (a) Wang et al ENSG00000184787 ENSG00000171791 ENSG00000145386 ENSG00000124762 ENSG00000117399 ENSG00000166508 ENSG00000112312 ENSG00000198901 ENSG00000171720 ENSG00000082175 ENSG00000078900 ENSG00000132646 ENSG00000026508 ENSG00000123374 ENSG00000106628 ENSG00000140464 ENSG00000080839 PMC8704137__F4 Ferroptosis in Non-Small Cell Lung Cancer: Progression and Therapeutic Potential on It ENSG00000168003 ENSG00000151012 PMC9715766__F2 Gut microbiota, pathogenic proteins and neurodegenerative diseases ENSG00000162711 ENSG00000164430 ENSG00000172936 ENSG00000136869 PMC9245541__F2 How Do Pollen Allergens Sensitize? ENSG00000158473 ENSG00000137033 ENSG00000145777 ENSG00000166090 PMC1525234__F6 Working model of regulatory mechanisms controlling cell death in response to mating pheromones ENSG00000101871 ENSG00000115419 PMC5257007__F3 Genomes of Fasciola hepatica from the Americas Reveal Colonization with Neorickettsia Endobacteria Related to the Agents of Potomac Horse and Human Sennetsu Fevers ENSG00000175198 ENSG00000114054 ENSG00000172005 PMC3523822__F1 Biosynthetic pathway of diphthamide in eukaryotes ENSG00000148399 ENSG00000134146 ENSG00000154813 ENSG00000108963 PMC5040452__F13 Impact of Heat Stress on Cellular and Transcriptional Adaptation of Mammary Epithelial Cells in Riverine Buffalo (Bubalus Bubalis) ENSG00000081041 ENSG00000111537 ENSG00000105329 ENSG00000108342 ENSG00000164400 PMC3929252__F1 Estrogen, HER2 signalling, and the PI3K/Akt pathway in drug-resistant breast cancer.Notes: ER can activate gene transcription by nuclear translocatin following ligand binding (1) or as a result of receptor phosphorylation in the absence of ligand (2) ENSG00000002330 ENSG00000291971 ENSG00000140443 PMC10296711__F12 Schematic illustration of the IL1-R/TLR/NFKB pathway with emphasis on activation of different NFKB subunits via the IRAK1/TRAF6-mediated pathway ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000090376 ENSG00000184216 PMC10296711__F10 Molecular Basis and Clinical Consequences of Chronic Inflammation in Prostatic Diseases: Prostatitis, Benign Prostatic Hyperplasia, and Prostate Cancer ENSG00000174123 ENSG00000174125 ENSG00000087586 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000136997 ENSG00000134070 ENSG00000136869 ENSG00000172936 ENSG00000175104 ENSG00000090376 ENSG00000184216 ENSG00000164342 PMC7174405__F1 Key proteins and important processes in vertebrate HH signaling pathway ENSG00000154309 ENSG00000128602 PMC2820748__F6 Sites within the early steps of the insulin signaling pathway affected by OGT and O-GlcNAcylation ENSG00000147162 ENSG00000185591 ENSG00000168610 PMC7827067__F2 Pathway map of PIK3CA/AKT ENSG00000140992 ENSG00000002330 ENSG00000100906 ENSG00000058091 ENSG00000173039 ENSG00000203710 ENSG00000250506 ENSG00000166484 ENSG00000095777 ENSG00000169291 ENSG00000141503 ENSG00000123374 ENSG00000001626 PMC5379071__F4 Proteogenomic integration reveals therapeutic targets in breast cancer xenografts ENSG00000171759 PMC7417632__F7 Hypothetical molecular mechanism of the H19/miR-29a/Wnt signaling pathway in HF inducibility of DP cells ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC2867902__F6 A feed forward loop for nutritional regulation of PNPLA3 ENSG00000170522 ENSG00000100344 ENSG00000099194 ENSG00000026103 PMC4303448__F1 The IKB kinase complex in NFKB regulation and beyond PMC8353268__F4 Quantitative developmental biology in vitro using micropatterning ENSG00000183979 ENSG00000183691 ENSG00000156574 PMC8826716__F10 Transmembrane p24 trafficking protein 2 regulates inflammation through the TLR4/NFKB signaling pathway in lung adenocarcinoma ENSG00000136869 ENSG00000146648 PMC9310369__F1 Main mechanisms of mitochondrial DAMP signalling ENSG00000104856 ENSG00000171855 ENSG00000134982 ENSG00000173039 ENSG00000089041 ENSG00000276561 ENSG00000183735 ENSG00000158473 ENSG00000239732 ENSG00000132591 ENSG00000164430 ENSG00000088888 ENSG00000125538 ENSG00000110218 PMC4598605__F5 Diagrammatic representation of mammalian target of rapamycin pathway: A crucial intersection of type 2 diabetes and Alzheimer’s disease ENSG00000198793 PMC4852538__F2 Pathway association between TH and metabolic process via ABCC8 (Kir6.2) (A) ENSG00000162889 ENSG00000006071 ENSG00000125740 ENSG00000185386 ENSG00000177606 ENSG00000165059 ENSG00000164690 ENSG00000162772 ENSG00000123268 PMC10311505__F3 YAP at the progression of inflammation ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000107201 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC4970609__F10 Roles of hBVR in activating IRK/PI3K/Akt pathway ENSG00000105723 ENSG00000156273 PMC6468556__F4 Model for HCV assembly and release ENSG00000011198 ENSG00000285482 ENSG00000062282 PMC3854349__F1 Biochemical adaptations of mammalian hibernation and naturally induced reversible insulin resistance ENSG00000169047 PMC10033682__F3 Ethyl acetate extract of Wenxia Changfu Formula inhibits the carcinogenesis of lung adenocarcinoma by regulating PI3K-AKT signaling pathway ENSG00000087245 ENSG00000140564 ENSG00000188822 ENSG00000010322 ENSG00000130234 ENSG00000015285 ENSG00000115661 ENSG00000127948 PMC12180163__F13 Pathways of action of ESPs intervention to alleviate UC in mice ENSG00000137033 ENSG00000138798 ENSG00000166090 ENSG00000277641 ENSG00000293532 PMC10033682__F4 Ethyl acetate extract of Wenxia Changfu Formula inhibits the carcinogenesis of lung adenocarcinoma by regulating PI3K-AKT signaling pathway ENSG00000163464 ENSG00000087245 ENSG00000142230 ENSG00000086991 ENSG00000137193 ENSG00000171791 ENSG00000118777 ENSG00000149295 ENSG00000106546 ENSG00000158125 ENSG00000276825 ENSG00000122025 ENSG00000156110 ENSG00000157227 ENSG00000129214 ENSG00000174197 ENSG00000100985 ENSG00000146648 ENSG00000105723 PMC3216306__F1 Downregulation of macrophages signalling by Leishmania infection ENSG00000183735 ENSG00000170458 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC6338098__F2 TGF-beta signalling in bovine mammary gland involution and a comparative assessment of MAC-T and BME-UV1 cells as in vitro models for its study ENSG00000002330 ENSG00000105329 PMC4801794__F2 PI3K/AKT/mTOR signaling pathways ENSG00000169047 ENSG00000198793 ENSG00000164327 PMC11435552__F1 Suppression of Interferon Response and Antiviral Strategies of Bunyaviruses ENSG00000183735 ENSG00000088888 ENSG00000187608 ENSG00000101782 ENSG00000145321 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 ENSG00000172183 PMC4158873__F2 O-GlcNAc and cancer metabolism ENSG00000074800 ENSG00000147162 ENSG00000198793 ENSG00000284194 ENSG00000115419 ENSG00000026103 PMC5082879__F3 Systems Biology Comparison of Ovarian Cancers Implicates Putative Somatic Driver Mutations through Protein-Protein Interaction Models ENSG00000115484 ENSG00000166167 ENSG00000259207 ENSG00000181163 ENSG00000169439 ENSG00000101057 ENSG00000107447 ENSG00000163918 ENSG00000138759 ENSG00000127191 ENSG00000168610 ENSG00000064933 ENSG00000012048 ENSG00000113328 ENSG00000115884 ENSG00000173372 ENSG00000083635 ENSG00000132646 ENSG00000136997 ENSG00000004897 ENSG00000149554 ENSG00000158859 PMC11435552__F2 DBV and GTV suppressing the IFN antiviral system by NS sequestration of key signaling molecules into IBs or FSs ENSG00000183735 ENSG00000088888 ENSG00000115415 ENSG00000121060 ENSG00000276561 PMC4158873__F3 PI3K/Akt/mTOR signaling pathway ENSG00000147162 ENSG00000198793 ENSG00000164327 PMC5082879__F2 Systems Biology Comparison of Ovarian Cancers Implicates Putative Somatic Driver Mutations through Protein-Protein Interaction Models ENSG00000136158 ENSG00000163939 ENSG00000042832 ENSG00000111859 ENSG00000120875 ENSG00000101057 ENSG00000137642 ENSG00000117724 ENSG00000138778 ENSG00000117122 ENSG00000125398 ENSG00000164056 ENSG00000104783 ENSG00000003989 ENSG00000115415 ENSG00000175745 ENSG00000143320 ENSG00000109805 ENSG00000165023 ENSG00000163879 ENSG00000022267 ENSG00000112759 ENSG00000006016 ENSG00000187678 PMC10216404__F2 Effects of RSV on activation of SIRT1 signalling pathway ENSG00000178860 ENSG00000125398 ENSG00000096717 ENSG00000131196 PMC9007691__F6 Epithelial Membrane Protein 1 Promotes Sensitivity to RSL3-Induced Ferroptosis and Intensifies Gefitinib Resistance in Head and Neck Cancer ENSG00000134531 PMC12246835__F3 Underlying renoprotective mechanisms of anthraquinones by regulating IƙB/NF-ƙB, Keap1/Nrf2 and PI3K/Akt/mTOR signaling pathways ENSG00000147162 ENSG00000181019 ENSG00000100387 ENSG00000198793 ENSG00000023909 ENSG00000079999 PMC4471883__F7 TLR4 signalling pathway to alleviate microglial activation ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000171791 PMC10216404__F4 Effects of RSV on the regulation of microRNAs and BMP2 signalling in protecting bone ENSG00000178860 ENSG00000086991 PMC12246835__F2 Underlying renoprotective mechanisms of anthraquinones by inhibiting TGFB1/Smad and Wnt1/Beta-catenin signaling pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11172918__F4 Ouabain–NKA-induced changes in epithelial cultured cells MDCK ENSG00000291971 ENSG00000198793 PMC8219020__F1 Live-attenuated oral polio vaccine as a potential source of protection against COVID-19 – Review of literature ENSG00000181847 ENSG00000134982 ENSG00000150637 PMC5625110__F1 Src family kinase signaling in renal fibrosis ENSG00000291971 ENSG00000010810 ENSG00000168610 ENSG00000146648 PMC7583949__F2 Macrophages in cardiac fibrosis ENSG00000170458 ENSG00000277943 PMC4564869__F3 Quantitative Phosphoproteomics Reveals Crosstalk Between Phosphorylation and O-GlcNAc in the DNA Damage Response Pathway ENSG00000147162 ENSG00000260428 PMC11172918__F3 Different signaling pathways activated by the binding of CGs and ROS to NKS ENSG00000167323 ENSG00000291971 ENSG00000293604 ENSG00000198793 ENSG00000146648 PMC7549352__F1 miRNA biogenesis: the canonical pathway begins with the transcription of miRNA genes to form the pri-miRNA ENSG00000102034 ENSG00000135473 ENSG00000152520 ENSG00000128191 ENSG00000113360 PMC6870983__F2 Schematic model of the mechanism of HuR-regulated tumor cell migration ENSG00000109814 ENSG00000124216 ENSG00000105329 ENSG00000168461 ENSG00000100985 ENSG00000096717 ENSG00000146648 PMC6079259__F2 Mechanism of Homologous Recombination (HR) ENSG00000149311 ENSG00000051180 PMC4578617__F1 miRNAs that control signaling governing osteogenesis and adipogenesis ENSG00000178860 ENSG00000170365 ENSG00000168036 PMC7864218__F3 Intersection of Mechanotransduction and Regenerative Osteogenic Materials ENSG00000087095 ENSG00000070831 ENSG00000134982 ENSG00000168036 PMC8532088__F2 Influenza virus RNA polymerase as an innate immune agonist and antagonist ENSG00000183735 ENSG00000188554 ENSG00000088888 ENSG00000104228 ENSG00000131323 ENSG00000121060 ENSG00000276561 PMC10755185__F6 Transcriptome Changes and Metabolic Outcomes After Bariatric Surgery in Adults With Obesity and Type 2 Diabetes ENSG00000142192 ENSG00000105835 ENSG00000177674 ENSG00000137845 PMC2824768__F4 Entry into an ICL repair pathway depends on the mode of recognition ENSG00000162733 PMC8000576__F2 Mechanisms by which MYC induces apoptosis ENSG00000141867 ENSG00000136997 ENSG00000120868 PMC8000576__F1 BCL-2-regulated apoptotic pathway ENSG00000100290 ENSG00000002330 ENSG00000135116 ENSG00000104081 PMC8430060__F5 Gene expression patterns of neuronal cells reveal the pathogenesis of autism ENSG00000196549 ENSG00000276051 ENSG00000112715 ENSG00000146648 PMC3513217__F2 Schematic illustration of irinotecan disposition pathway ENSG00000134982 ENSG00000103222 ENSG00000118777 ENSG00000023839 PMC3513217__F3 Metabolism pathway of tamoxifen and its interaction with estrogen receptors.Copyright © 2009 ENSG00000196502 ENSG00000165841 ENSG00000197408 ENSG00000140505 PMC9243258__F4 R-loop Mediated DNA Damage and Impaired DNA Repair in Spinal Muscular Atrophy ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000107290 ENSG00000138385 PMC11556706__F1 Phase regulation of Ca2+-cAMP oscillation and corresponding mathematical modeling ENSG00000108599 PMC2666503__F1 F igure 1.— PMC9260753__F6 Network Pharmacology Experiments Show That Emodin Can Exert a Protective Effect on MCAO Rats by Regulating Hif-1A/VEGF-A Signaling ENSG00000172831 ENSG00000167601 ENSG00000114200 ENSG00000169239 ENSG00000178999 ENSG00000140505 ENSG00000130649 ENSG00000173039 ENSG00000169710 ENSG00000171791 ENSG00000118777 ENSG00000106546 ENSG00000158125 ENSG00000291470 ENSG00000239732 ENSG00000185015 ENSG00000107854 ENSG00000128052 ENSG00000021461 ENSG00000105810 ENSG00000160870 ENSG00000275565 ENSG00000146648 PMC4087671__F1 Control of the TRAF6 signalosome by miR-146a ENSG00000115415 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000121966 PMC7791871__F7 YAP manipulates proliferation via PTEN/AKT/mTOR-mediated autophagy in lung adenocarcinomas ENSG00000198793 ENSG00000150457 ENSG00000131023 PMC5548460__F1 Beyond transcription factors: how oncogenic signaling reshapes the epigenetic landscape ENSG00000135363 PMC3423122__F10 Transcriptome of genes encoding enzymes and proteins on the lactose synthesis pathway, including GLUT1, HK1, PGM1, UGP2, GALE, GALT, SLC35A2, LALBA, and B4-GALT1, -3, and -5 ENSG00000292209 PMC3423122__F11 Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans ENSG00000172216 ENSG00000115415 ENSG00000185591 ENSG00000125347 ENSG00000292209 ENSG00000168610 ENSG00000113494 PMC8217661__F2 Wiskott-Aldrich Syndrome Protein: Roles in Signal Transduction in T Cells ENSG00000134982 ENSG00000113263 ENSG00000099942 PMC2483283__F2 Coexpression of genes within three core metabolic pathways ENSG00000060982 ENSG00000102575 ENSG00000142513 ENSG00000128928 PMC8267412__F2 Expression and Role of Heparan Sulfated Proteoglycans in Pancreatic Cancer ENSG00000154342 ENSG00000168036 ENSG00000179399 PMC8267412__F3 Expression and Role of Heparan Sulfated Proteoglycans in Pancreatic Cancer ENSG00000115884 ENSG00000165527 ENSG00000125637 PMC6912266__F1 Potential intracellular target points for (i) acute alcohol and (ii) chronic alcohol in a stylized cell ENSG00000104856 ENSG00000162711 ENSG00000172936 ENSG00000162924 ENSG00000005381 ENSG00000175104 ENSG00000184216 PMC3860520__F3 Toll-like receptor (TLR)-4 signaling pathway in alcoholic liver disease ENSG00000183735 ENSG00000172936 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC7687005__F8 Mechanistic diagrams indicate that in osteoporosis, miR‐497 could promote osteoblast proliferation and collagen synthesis, and inhibit osteoblast apoptosis through inhibiting LRG1 and activating TGF‐B1/Smads signalling pathway PMC2483283__F4 Coexpression of the genes for fatty acid biosynthesis ENSG00000102575 ENSG00000142513 PMC6009972__F11 ML141-induced hepatocyte differentiation ENSG00000154342 ENSG00000070831 ENSG00000168036 ENSG00000163631 PMC2483283__F5 Leucine degradation pathway in mitochondria ENSG00000171444 ENSG00000060982 ENSG00000128928 ENSG00000105552 PMC9607901__F3 Recent advances in the diagnostic and therapeutic roles of microRNAs in colorectal cancer progression and metastasis ENSG00000102871 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000127191 ENSG00000118971 ENSG00000168610 ENSG00000146648 PMC8908266__F1 Deubiquitinases in Virus Replication and Host Innate Immune Response ENSG00000135655 ENSG00000213928 ENSG00000164164 ENSG00000036672 ENSG00000172046 ENSG00000164663 ENSG00000169914 ENSG00000155313 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000165312 ENSG00000162607 ENSG00000273820 ENSG00000174125 ENSG00000154124 ENSG00000276561 ENSG00000184979 ENSG00000136878 ENSG00000187554 ENSG00000172936 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000277276 PMC7891831__F1 Enzymatic cascade of the renin-angiotensin system (RAS) and the key receptor systems ENSG00000130234 PMC5050041__F1 Neuregulin 1 - erbB4 pathway in schizophrenia: From genes to an interactome ENSG00000047579 ENSG00000291971 ENSG00000010810 ENSG00000117152 PMC10548138__F2 PI3K /Akt in COPD regulation PMC4114321__F3 Regulation of homologous recombination in eukaryotes ENSG00000149311 ENSG00000175054 ENSG00000261832 ENSG00000164053 ENSG00000136425 ENSG00000141977 ENSG00000132646 ENSG00000157884 ENSG00000051180 ENSG00000139618 PMC10548138__F1 Transduction and regulatory pathways of PI3K/Akt pathway ENSG00000109452 ENSG00000005882 PMC6325760__F1 Schematic diagram showing PR/RANKL pathway and downstream RANK-mediated signaling in mammary epithelial cells ENSG00000138798 ENSG00000127191 ENSG00000146648 PMC6995173__F7 NAMPT’s role in the proliferation of human CRC cells through the regulation of Wnt/Beta-catenin signaling ENSG00000105835 ENSG00000134982 ENSG00000168036 PMC3189169__F1 Toll-like receptor (TLR) and type I interferon (IFN) signaling pathways ENSG00000183735 ENSG00000213928 ENSG00000239732 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000120242 ENSG00000164342 PMC11786412__F7 Reconstruction the sex determination regulatory pathway involving amhr2 ENSG00000162552 ENSG00000104899 ENSG00000137090 ENSG00000135409 ENSG00000176387 PMC8195904__F2 Adamantinomatous craniopharyngioma as a model to understand paracrine and senescence-induced tumourigenesis ENSG00000134982 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC8458763__F5 Mechanobiology of Endothelial-to-Mesenchymal Transition in Cardiovascular Disease ENSG00000182718 ENSG00000103335 PMC6450552__F2 Systematic illustration of PGRN-mediated signaling pathways ENSG00000142627 ENSG00000184481 ENSG00000168610 PMC8392110__F1 Targeting STAT3 Signaling Pathway in Colorectal Cancer ENSG00000291971 ENSG00000138798 ENSG00000168610 PMC9496369__F1 Oxidative Stress and NRF2/KEAP1/ARE Pathway in Diabetic Kidney Disease (DKD): New Perspectives ENSG00000162692 ENSG00000146648 PMC9522619__F7 Properties of flavonoids in the treatment of bladder cancer (Review) ENSG00000115216 ENSG00000198793 ENSG00000026508 ENSG00000100985 ENSG00000096717 PMC6041267__F8 A schematic model of mitochondrial distribution regulated by the Arf6–AMAP1–ILK pathway ENSG00000126858 ENSG00000115993 ENSG00000165527 ENSG00000182606 ENSG00000105287 PMC9522619__F2 Properties of flavonoids in the treatment of bladder cancer (Review) ENSG00000123395 ENSG00000126775 ENSG00000102871 ENSG00000167468 ENSG00000198793 ENSG00000168040 ENSG00000115107 ENSG00000026103 PMC9522619__F3 Properties of flavonoids in the treatment of bladder cancer (Review) ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000164690 ENSG00000128602 ENSG00000168610 PMC9522619__F5 Properties of flavonoids in the treatment of bladder cancer (Review) ENSG00000087245 ENSG00000128272 ENSG00000291971 ENSG00000198793 ENSG00000167996 ENSG00000166851 ENSG00000168610 PMC3412276__F1 Mannose metabolism in Trypanosoma brucei PMC9522619__F1 Properties of flavonoids in the treatment of bladder cancer (Review) ENSG00000149311 ENSG00000175054 ENSG00000123374 ENSG00000166851 PMC3962548__F4 Controlling clot formation ENSG00000003436 ENSG00000134982 ENSG00000173599 PMC3798018__F1 PLD and phosphatidic acid in the cell ENSG00000129219 ENSG00000291971 ENSG00000198793 ENSG00000163914 ENSG00000173599 PMC8329951__F6 Identification of differentially expressed genes in diabetic kidney disease by RNA‐Seq analysis of venous blood platelets ENSG00000134460 ENSG00000140287 ENSG00000147647 ENSG00000128342 ENSG00000084774 ENSG00000016402 PMC3354586__F3 Ingenuity pathway analysis (IPA) identified critical expression networks containing genes that are significantly correlated with the extent of necrosis in The Cancer Genome Atlas (TCGA) glioblastoma (GBM) samples from all subclasses (A and B) ENSG00000104856 ENSG00000177575 ENSG00000128016 ENSG00000143546 ENSG00000169896 ENSG00000059804 ENSG00000070495 ENSG00000141458 ENSG00000168610 ENSG00000011422 ENSG00000172216 ENSG00000118503 ENSG00000171435 PMC5027135__F4 A new model of MC4R microcircuitry ENSG00000115138 ENSG00000166603 PMC5432127__F1A Maternal obesity on placental function and fetal development ENSG00000169047 ENSG00000198793 ENSG00000159346 ENSG00000285070 PMC3275548__F3 Liver from Campari tomato treatment ENSG00000134982 ENSG00000168036 ENSG00000123104 ENSG00000176105 ENSG00000106688 ENSG00000138686 ENSG00000180210 ENSG00000123496 ENSG00000130164 ENSG00000154122 ENSG00000150907 ENSG00000167967 ENSG00000118520 ENSG00000139687 ENSG00000166974 ENSG00000173171 ENSG00000132305 ENSG00000102967 ENSG00000132170 ENSG00000128654 ENSG00000084764 ENSG00000185946 ENSG00000013810 ENSG00000075891 ENSG00000135363 ENSG00000067191 ENSG00000136872 ENSG00000198911 PMC3890531__F5 VEGF and NOTCH signaling pathways ENSG00000148400 ENSG00000074181 ENSG00000145321 ENSG00000112715 PMC8448420__F2 Autophagy and Mitochondrial Homeostasis During Infection: A Double-Edged Sword ENSG00000198793 ENSG00000131323 ENSG00000130159 ENSG00000150455 ENSG00000175104 PMC5362546__F2 Long non-coding RNAs in nasopharyngeal carcinoma: As systemic review ENSG00000185236 ENSG00000112242 ENSG00000103769 ENSG00000084733 ENSG00000108518 PMC9496180__F8 Fibrotic Response of Human Trabecular Meshwork Cells to Transforming Growth Factor-Beta 3 and Autotaxin in Aqueous Humor ENSG00000163914 ENSG00000198670 ENSG00000108821 ENSG00000168610 PMC8259730__F1 Precision Medicine for Paediatric Severe Asthma: Current Status and Future Direction [Corrigendum] ENSG00000137033 ENSG00000145777 ENSG00000166090 PMC2761106__F8 BMP7 signaling in the NZ ENSG00000170365 ENSG00000125968 PMC2743934__F8 Elongation Factor 2 and Fragile X Mental Retardation Protein Control the Dynamic Translation of Arc/Arg3.1 Essential for mGluR-LTD ENSG00000284161 ENSG00000198576 ENSG00000167658 PMC2990979__F1 Portions of the pathway utilized in Beta-branching are highlighted with color in this depiction of the bryostatin biosynthetic pathway ENSG00000132478 PMC8346058__F2 Targeting Inflammation after Myocardial Infarction: A Therapeutic Opportunity for Extracellular Vesicles? ENSG00000162711 ENSG00000153208 ENSG00000173372 ENSG00000172936 ENSG00000170989 ENSG00000121807 ENSG00000175104 ENSG00000184216 PMC7255381__F4 Signaling of the VEGF Ligands, Receptors, and the Inhibitors of the VEGFA Pathway ENSG00000112715 ENSG00000118257 PMC3427656__F1 GH-STAT5 signaling pathway ENSG00000112964 ENSG00000124762 PMC7016858__F1 Biogenesis and heterogeneity of tumor-derived extracellular vesicles ENSG00000085117 ENSG00000110651 ENSG00000010278 ENSG00000135404 ENSG00000123908 PMC7924189__F6 Mechanism of rice blast resistance in Tetep at cellular level ENSG00000105722 ENSG00000167419 PMC3910266__F2 NOD1 signaling and interactions with Rho GTPases and NFATc ENSG00000070831 ENSG00000106100 PMC7854028__F1 miRNAs participate in the regulation of key genes related to cellular response to IR ENSG00000149311 ENSG00000175054 ENSG00000198793 ENSG00000146648 ENSG00000253729 PMC8931289__F9 Tear miRNAs Identified in a Murine Model of Sjögren’s Syndrome as Potential Diagnostic Biomarkers and Indicators of Disease Mechanism ENSG00000162433 ENSG00000072274 ENSG00000171791 ENSG00000165527 ENSG00000171388 ENSG00000177182 ENSG00000115112 ENSG00000291814 ENSG00000077782 ENSG00000162889 ENSG00000143420 ENSG00000137757 ENSG00000097096 ENSG00000100526 ENSG00000132693 ENSG00000170458 ENSG00000175899 ENSG00000189043 ENSG00000119537 ENSG00000175104 ENSG00000170779 ENSG00000101115 ENSG00000100744 ENSG00000188846 ENSG00000198265 ENSG00000137393 ENSG00000118971 ENSG00000166068 ENSG00000291802 ENSG00000171735 ENSG00000166292 ENSG00000130222 ENSG00000171105 ENSG00000182712 ENSG00000213465 ENSG00000103035 ENSG00000152382 ENSG00000155858 ENSG00000151893 ENSG00000004534 ENSG00000232629 ENSG00000132478 ENSG00000114698 ENSG00000127191 ENSG00000132664 ENSG00000168610 ENSG00000132300 ENSG00000100418 ENSG00000014914 ENSG00000254550 ENSG00000008283 ENSG00000125775 ENSG00000105058 ENSG00000117020 ENSG00000168564 ENSG00000147099 ENSG00000102893 ENSG00000149554 PMC12058831__F5 Investigation of the mechanism of Buyang Huanwu decoction in improving learning and memory impairment in Alzheimer's disease mice based on lipidomics ENSG00000018510 ENSG00000111666 ENSG00000116906 PMC2746747__F1 Molecular ablation of TGFB signaling pathways by tyrosine kinase inhibition: The coming of a promising new era in the treatment of tissue fibrosis ENSG00000170365 PMC5709847__F2 Regulatory mechanism of expression of DNA damage response genes by the checkpoint pathway PMC7854028__F3 IR-induced modulation of miRNAs initials carcinogenesis ENSG00000186716 PMC5709847__F1 Checkpoint cascade in S PMC9393691__F4 Metabolic rewiring directs melanoma immunology ENSG00000089692 ENSG00000049768 ENSG00000106546 PMC6113440__F3 Modified chlorambucil (Chb‐M') as a safe lead compound of novel anticancer drug therapy ENSG00000159216 ENSG00000020633 ENSG00000067955 PMC9157603__F6 Soluble factors secreted by human Wharton’s jelly mesenchymal stromal/stem cells exhibit therapeutic radioprotection: A mechanistic study with integrating network biology ENSG00000143839 ENSG00000228672 PMC6528848__F1 Different regulatory mechanisms of BANCR in different human malignancy ENSG00000087245 ENSG00000171720 ENSG00000170558 ENSG00000165409 PMC6639196__F4 Conceivable migration pathway related to PNETs based on literatures ENSG00000148346 ENSG00000137673 ENSG00000198793 ENSG00000166509 ENSG00000184363 PMC5532371__F8 A possible pathway for pre-miR-199a-mediated regulation of HSV-1 secondary envelopment ENSG00000070831 ENSG00000143761 ENSG00000107863 PMC7730500__F1 Schematic diagram illustrating the steps and enzymes involved in the base excision repair (BER) pathway ENSG00000143799 ENSG00000109674 ENSG00000292286 ENSG00000039650 ENSG00000291803 ENSG00000105486 ENSG00000132781 ENSG00000168066 ENSG00000132646 ENSG00000165392 ENSG00000123415 ENSG00000197299 ENSG00000129071 ENSG00000139372 ENSG00000140398 ENSG00000042088 ENSG00000227345 PMC5922992__F1 Nucleotide-binding oligomerization domain 1-mediated mucosal host defense against Helicobacter pylori infection ENSG00000169248 ENSG00000169245 ENSG00000138755 ENSG00000169429 ENSG00000131323 ENSG00000106100 ENSG00000276561 PMC7317091__F1 Summary of osteoclast differentiation induced by integration of CSF-1R, RANK, immunoreceptor-like and integrin receptor signaling ENSG00000182578 ENSG00000170909 ENSG00000134215 ENSG00000184371 ENSG00000197943 ENSG00000175104 ENSG00000131196 PMC11492689__F1 Roles of non-coding RNAs (ncRNAs) in host response to PRRSV infection ENSG00000140319 ENSG00000177575 ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000168610 ENSG00000276561 ENSG00000164342 PMC8501630__F5 Whole genome copy number analyses reveal a highly aberrant genome in TP53 mutant lung adenocarcinoma tumors ENSG00000163435 ENSG00000171105 ENSG00000198793 ENSG00000163914 ENSG00000173599 PMC11492689__F2 Roles of ncRNAs in host response to PRRSV infection ENSG00000117020 ENSG00000125347 ENSG00000276561 PMC9613904__F8 Proteostatic consequences of PKB/Akt-mTORC1 pathway manipulation in muscle ENSG00000177169 ENSG00000169047 PMC11837477__F10 EGFR roles in fetal and postnatal pancreas development ENSG00000291971 ENSG00000113070 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC11010095__F8 The pivotal role of CTRP9 in reendothelialization of EPCs and the protective mechanisms of AMPK‐mediated Akt/eNOS signaling involved in adipoR1 and N‐cadherin receptor ENSG00000170558 ENSG00000159346 ENSG00000285070 PMC9355085__F3 Epigenetic regulation and T-cell responses in endometriosis – something other than autoimmunity ENSG00000104856 ENSG00000100290 ENSG00000205221 ENSG00000182568 ENSG00000134982 ENSG00000088305 ENSG00000198793 ENSG00000137265 ENSG00000164327 ENSG00000049768 PMC11834966__F3 Action of PRMT3 and CARM1 in different cancer ENSG00000100811 ENSG00000145388 ENSG00000147862 ENSG00000198793 ENSG00000112561 ENSG00000142453 ENSG00000168036 ENSG00000112715 ENSG00000136997 ENSG00000167468 ENSG00000114268 ENSG00000145321 ENSG00000139842 ENSG00000170779 PMC6337236__F2 Iron handling in the tumor microenvironment ENSG00000177575 ENSG00000148346 ENSG00000170365 ENSG00000111537 ENSG00000089472 ENSG00000138798 ENSG00000125538 ENSG00000105697 ENSG00000168610 PMC9198488__F2 Key Role of RNA Modification in Breast Cancer ENSG00000145388 ENSG00000152661 ENSG00000198492 ENSG00000170558 ENSG00000197405 ENSG00000168036 ENSG00000087586 ENSG00000091542 ENSG00000146457 ENSG00000135480 ENSG00000136231 ENSG00000159167 ENSG00000074800 ENSG00000149658 ENSG00000073792 ENSG00000165819 ENSG00000113360 PMC5727541__F4 2-hydroxyisobutyrylated enzymes involved in TCA cycle, pentose phosphate pathway, pyruvate metabolism, glycolysis/gluconeogenesis and starch biosynthesis pathways ENSG00000197713 ENSG00000073578 ENSG00000153574 ENSG00000105953 ENSG00000091140 PMC11837477__F13 EGFR roles in lung fibrosis ENSG00000109321 ENSG00000138798 ENSG00000146648 PMC4713620__F2 Model of RNF43-regulated p53 cell cycling pathway ENSG00000108375 PMC2955448__F1 Pathogenesis of prostate cancer: from molecular to metabolic alterations ENSG00000131473 ENSG00000113161 ENSG00000026103 PMC10539878__F3 Sterile inflammation and the NLRP3 inflammasome in cardiometabolic disease ENSG00000278718 ENSG00000162711 ENSG00000185515 ENSG00000088888 ENSG00000103490 ENSG00000116688 ENSG00000036828 ENSG00000168040 ENSG00000159335 ENSG00000115594 PMC2896848__F2 Alternate and peripheral androgen synthesis pathways PMC8465606__F7 Ascorbic Acid Regulates the Immunity, Anti-Oxidation and Apoptosis in Abalone Haliotis discus hannai Ino ENSG00000125538 ENSG00000132478 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000076604 PMC2784121__F6 NPM-ALK oncogenic tyrosine kinase controls T cell identity by transcriptional regulation and epigenetic silencing in lymphoma cells ENSG00000291603 ENSG00000213658 ENSG00000070831 ENSG00000134215 ENSG00000168610 ENSG00000141968 PMC12217521__F6 The paracrine effects of Mac-ADSCs ENSG00000019991 ENSG00000112715 ENSG00000121879 PMC3131451__F1 The PI3K/mTOR signaling pathway highlighting the phosphorylation sites tested in our cellular and biochemical assays ENSG00000198793 PMC10040407__F8 Exosomes secreted from cardiomyocytes suppress the sensitivity of tumor ferroptosis in ischemic heart failure ENSG00000167468 PMC8792742__F2 Inflammasome Activation in Pulmonary Arterial Hypertension ENSG00000278718 ENSG00000125538 ENSG00000189403 ENSG00000136869 PMC9372260__F4 Integrated analysis of multiple bioinformatics studies to identify microRNA-target gene-transcription factor regulatory networks in retinoblastoma ENSG00000136492 ENSG00000094804 ENSG00000171848 ENSG00000112118 ENSG00000171793 ENSG00000075218 ENSG00000073111 ENSG00000076003 ENSG00000117399 ENSG00000166508 ENSG00000093009 PMC6522569__F2 Beyond PD-1 Immunotherapy in Malignant Melanoma ENSG00000089692 PMC4413906__F2 Progesterone receptor signaling in the initiation of pregnancy and preservation of a healthy uterus ENSG00000082175 ENSG00000291971 PMC6568338__F8 Adhesion-dependent and -independent pathways leading to DNA synthesis in ET-1-treated astrocytes ENSG00000291971 ENSG00000163914 PMC9688773__F8 Lipid Dys-Homeostasis Contributes to APOE4-Associated AD Pathology ENSG00000185813 ENSG00000116133 ENSG00000172893 ENSG00000173599 ENSG00000113161 ENSG00000133027 PMC10535041__F5 Antagonistic Activity of Oroxylin A against Fusarium graminearum and Its Inhibitory Effect on Zearalenone Production ENSG00000100412 ENSG00000153574 PMC3621013__F5 Control of Alternative Splicing in Immune Responses: Many Regulators, Many Predictions, Much Still to Learn ENSG00000138795 ENSG00000026508 ENSG00000048740 PMC2770326__F6 Selective pathway utilization of analogs is ensured by the nonpermissivity of enzymes at critical junctures ENSG00000159921 ENSG00000156958 ENSG00000254685 ENSG00000172269 ENSG00000102032 PMC12034657__F4 PI3K/AKT/mTOR signaling pathway activated by Sr ENSG00000198793 ENSG00000036828 ENSG00000167182 PMC2770326__F4 Pathway options for sialic acid glycoengineering ENSG00000159921 ENSG00000100473 ENSG00000095380 PMC7952251__F2 Regulatory mechanism of aromatase and '2-cell, 2-gonadotropin hypothesis' ENSG00000172216 ENSG00000140443 PMC5864864__F7 Proposed model of the temporal contributions of Wnt ligands and Beta-catenin to Alpha-galactosylceramide (Alpha-GalCer)-induced interferon gamma (IFNG) and IL-4 responses by liver natural killer T (NKT) cells ENSG00000134982 ENSG00000168036 ENSG00000104332 PMC9539487__F4 Partners in crime: Proteins implicated in RNA repeat expansion diseases ENSG00000143486 ENSG00000144895 ENSG00000066044 ENSG00000135387 ENSG00000106263 ENSG00000174953 ENSG00000132341 PMC4443896__F1A Activation of the JAK/STAT pathway in Behcet’s Disease ENSG00000172216 ENSG00000198793 PMC11595439__F3 The CWI signaling cascade ENSG00000126858 ENSG00000121058 ENSG00000185591 ENSG00000123268 PMC3500439__F1 Molecular Pathways: The Metabolic Regulator Estrogen-Related Receptor Alpha as a Therapeutic Target in Cancer ENSG00000100811 ENSG00000198793 ENSG00000113520 PMC7911116__F2 Lithium interactions with oxidative stress, inflammation and glutamatergic pathways ENSG00000171791 PMC2871634__F5 Regulation of apoptosis ENSG00000102871 ENSG00000149269 ENSG00000168040 ENSG00000127191 ENSG00000084774 ENSG00000026103 PMC8157630__F6 Identification of significant genes as prognostic markers and potential tumor suppressors in lung adenocarcinoma via bioinformatical analysis ENSG00000213658 ENSG00000070831 ENSG00000163914 ENSG00000171540 ENSG00000084774 PMC4319431__F1 Targeting the extrinsic apoptotic pathway in cancer: lessons learned and future directions ENSG00000115339 ENSG00000168040 ENSG00000127191 PMC7911116__F1 Activated and deactivated WNT pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4085981__F1 Positive feedback in cardioprotection: Can more mechanism lead to translation? ENSG00000198793 ENSG00000173599 ENSG00000164327 PMC2620272__F4 Bimodal genes that were switched "on" as a result of HIV infection in KEGG T-cell receptor signalling pathways ENSG00000135218 ENSG00000213658 ENSG00000010810 ENSG00000148204 ENSG00000163599 ENSG00000158825 ENSG00000113263 PMC3071786__F6 Changes in mRNA levels among various signalling pathway members following inhibition of FGFR activity ENSG00000134982 ENSG00000168036 ENSG00000162772 ENSG00000100219 ENSG00000185269 ENSG00000177283 ENSG00000121075 ENSG00000155760 ENSG00000100603 ENSG00000136158 ENSG00000005339 ENSG00000174804 ENSG00000277641 ENSG00000111145 ENSG00000117020 ENSG00000128272 ENSG00000164056 ENSG00000147099 ENSG00000156925 ENSG00000156427 ENSG00000019549 ENSG00000131264 ENSG00000134853 ENSG00000185668 ENSG00000076716 ENSG00000136160 ENSG00000149922 PMC9251686__F7 Receptor interacting protein 1 knockdown induces cell death in liver cancer by suppressing STAT3/ATR activation in a p53-dependent manner ENSG00000175054 ENSG00000137275 ENSG00000168610 PMC6527808__F1 Molecular pathogenesis of Epstein-Barr virus-positive NK/T-cell lymphoma ENSG00000136997 ENSG00000085382 ENSG00000130159 ENSG00000215301 PMC8416054__F2 Alternative Splicing: A New Cause and Potential Therapeutic Target in Autoimmune Disease ENSG00000138378 ENSG00000239732 ENSG00000169896 ENSG00000239998 ENSG00000118503 ENSG00000163599 ENSG00000172936 ENSG00000152689 ENSG00000143226 ENSG00000276561 ENSG00000184216 PMC8416054__F3 Alternative Splicing: A New Cause and Potential Therapeutic Target in Autoimmune Disease ENSG00000056558 ENSG00000026508 ENSG00000049768 ENSG00000175104 ENSG00000026103 PMC2819165__F2 Genetic Susceptibility to Lymphoma ENSG00000100906 ENSG00000136869 ENSG00000110324 ENSG00000118971 PMC2770326__F2 Mammalian sialic acid metabolism ENSG00000100522 ENSG00000064225 ENSG00000115488 ENSG00000008513 ENSG00000111728 ENSG00000070731 ENSG00000126091 ENSG00000073849 ENSG00000095380 ENSG00000159921 ENSG00000170191 ENSG00000162139 ENSG00000111726 ENSG00000133116 ENSG00000101638 ENSG00000148488 ENSG00000113532 ENSG00000013375 ENSG00000144057 PMC11058230__F7 A hypothetic model for signaling pathway alterations and cellular phenotypes in MPS II neurons ENSG00000109991 ENSG00000277586 ENSG00000137673 ENSG00000175592 ENSG00000168036 ENSG00000169432 ENSG00000168646 PMC5861197__F3 Paradigm of host inflammation responses to Salmonella and its interaction with autophagy as well as ubiquitination ENSG00000125538 ENSG00000142405 ENSG00000172936 ENSG00000131323 ENSG00000175104 PMC8168445__F1 Reactive astrocytes are a key component to neuroinflammation in AD ENSG00000168610 PMC5861197__F4 The similar activation process of autophagy and NFKB pathway in response to Salmonella ENSG00000123240 ENSG00000154124 PMC5343350__F7 Potential mechanisms involved in T helper type 17 (Th17) differentiation under T‐bet over‐expression conditions ENSG00000111537 ENSG00000159216 ENSG00000137265 ENSG00000106546 PMC6873406__F9 Non small cell lung cancer KEGG pathway ENSG00000068028 ENSG00000132906 ENSG00000189283 ENSG00000002330 ENSG00000105639 ENSG00000146648 ENSG00000122008 PMC3366822__F7 Schematic diagram showing the role of NDRG1 in inhibiting the EMT via regulation of the TGFB/SMAD and Wnt pathways ENSG00000168036 PMC3851951__F4 Microbiota impact on the epigenetic regulation of colorectal cancer ENSG00000100234 ENSG00000226275 ENSG00000020633 PMC6767051__F2 Cell cycle‐non specific mechanisms for the resistance to CDK4/6 inhibitors ENSG00000169554 ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 PMC7408838__F2 SRC-mediated molecular pathways formally assessed in malignant mesothelioma (MM) ENSG00000133110 ENSG00000291971 ENSG00000135446 ENSG00000105810 ENSG00000168610 PMC2871634__F4 WNT/Beta-catenin signaling pathway ENSG00000134982 ENSG00000165879 ENSG00000168036 PMC7819563__F3 Correlation between glucose metabolism and amino acid metabolism in tumor cells ENSG00000092621 ENSG00000166123 PMC6333678__F2 Signaling pathways activated after binding of E2 and G1 to GPER ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC5809440__F2 Assessment of liver microenvironment through whole-genome RNA Seq ENSG00000183735 ENSG00000138378 ENSG00000187608 ENSG00000137965 ENSG00000185745 ENSG00000115267 ENSG00000172936 ENSG00000142089 ENSG00000131323 ENSG00000111331 ENSG00000276561 PMC11294417__F10 Schematic diagram for NEK2 functions during porcine embryonic development ENSG00000012048 ENSG00000117650 ENSG00000281324 ENSG00000162337 ENSG00000134057 ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000123374 ENSG00000149554 ENSG00000253729 ENSG00000183765 PMC6245977__F1 RAS signaling pathway with proteins mutated in JMML in red ENSG00000033327 ENSG00000110395 ENSG00000198793 PMC7281231__F7 Schematic representation summarizing the impacts of PEDV ORF3 on NFKB and IFNB signaling cascades ENSG00000183735 ENSG00000088888 ENSG00000173039 ENSG00000276561 PMC6632210__F7 LPS-mediated platelet activation and TLR4 expression in canine platelets ENSG00000170458 ENSG00000136869 ENSG00000062485 PMC7343769__F1 Molecular mechanisms of chloroquine/hydroxychloroquine in pDCs ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000172936 PMC9320269__F4A Analyzing the Systems Biology Effects of COVID-19 mRNA Vaccines to Assess Their Safety and Putative Side Effects ENSG00000224320 PMC7488754__F1 Scheme of processes that maintain a certain receptor density on the postsynaptic membrane at the activated synapse ENSG00000292254 PMC8347170__F2 Autoimmune Responses in Oncology: Causes and Significance PMC3992631__F3 Comparison of gene expression in immobilized relative to planktonic yeast: (A) intermediary metabolism and (B) cell cycle ENSG00000074800 ENSG00000100412 ENSG00000099804 ENSG00000146701 PMC10526805__F3 Phosphoinositide Signaling by Scaffolds at Cytoplasmic Membranes ENSG00000140575 PMC10526805__F2 Phosphoinositide Signaling by Scaffolds at Cytoplasmic Membranes ENSG00000069869 ENSG00000143761 ENSG00000140575 ENSG00000136848 ENSG00000165527 ENSG00000104341 ENSG00000047849 ENSG00000146648 PMC8470522__F3 Actions and Roles of FSH in Germinative Cells ENSG00000171791 ENSG00000187772 ENSG00000172201 PMC4685420__F1 Schematic summarizing some of the genes and pathways known to influence c-Myc cap-independent translation in multiple myeloma (MM) ENSG00000280831 ENSG00000198793 PMC7819563__F2 Metabolic alterations in hepatocarcinoma ENSG00000107874 ENSG00000083720 PMC9424728__F9 Integrating physiology, genetics, and transcriptome to decipher a new thermo-sensitive and light-sensitive virescent leaf gene mutant in cucumber ENSG00000080819 ENSG00000126088 ENSG00000188690 ENSG00000127948 PMC4694793__F3 Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy ENSG00000019991 ENSG00000198793 ENSG00000171791 ENSG00000128602 ENSG00000146648 PMC7841926__F4 Illustration of the calcium signaling pathway induced by major putative targets of SMT ENSG00000182533 PMC12203940__F1 Wnt signaling pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC4964175__F1 Pharmacological targets of ibuprofen ENSG00000182175 PMC5890536__F9 RFc constructs on human complement ENSG00000244731 ENSG00000166278 PMC8106045__F1 Physiology and pathophysiology of copper transport and metabolism ENSG00000123191 ENSG00000177556 PMC4227521__F1 Erythropoietin receptor and signaling pathways ENSG00000169291 ENSG00000115415 ENSG00000187266 ENSG00000168610 PMC3980740__F5 Signaling circuit driving transformation and tumorigenesis ENSG00000291971 ENSG00000074181 ENSG00000168610 PMC1782564__F6 Hypothesized asthma cascade in hapten immune contact sensitized mice, consist of B-1 cell- to immunoglobulin M- (IgM) to complement-driven airway responses ENSG00000106546 ENSG00000062485 PMC4553261__F1 Data slicing and pathway enrichment analysis ENSG00000142192 PMC9654339__F3 In Vivo Models for Prostate Cancer Research ENSG00000157554 ENSG00000109685 ENSG00000121067 PMC9654339__F4 In Vivo Models for Prostate Cancer Research ENSG00000012048 ENSG00000111058 ENSG00000136997 ENSG00000170430 PMC9654339__F5 In Vivo Models for Prostate Cancer Research ENSG00000137673 ENSG00000157764 ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000168610 PMC4653709__F12 Proposed schematic representation showing the mechanism of ETH and its effect on neurogenesis ENSG00000134982 ENSG00000168036 ENSG00000105723 PMC11950527__F3 Annotated map of EM on PCa-related signaling pathways ENSG00000122025 ENSG00000148346 ENSG00000108691 ENSG00000149968 ENSG00000108688 ENSG00000131323 ENSG00000168040 ENSG00000155313 ENSG00000127191 ENSG00000143556 ENSG00000115009 ENSG00000122008 PMC7603200__F4 Connection between the PI3K/AKT/mTOR pathway and GLI activity ENSG00000106571 ENSG00000155792 PMC8281607__F2 Shark liver oil supplementation enriches endogenous plasmalogens and reduces markers of dyslipidemia and inflammation ENSG00000116906 ENSG00000180089 ENSG00000197601 ENSG00000133027 PMC11854706__F6 Signaling pathways induced and inhibited by ACE ENSG00000132906 ENSG00000112576 ENSG00000002330 ENSG00000134982 ENSG00000102871 ENSG00000168036 ENSG00000171791 ENSG00000168040 ENSG00000118971 ENSG00000121879 ENSG00000164305 ENSG00000148498 ENSG00000102981 ENSG00000120868 ENSG00000168646 ENSG00000064012 ENSG00000146648 ENSG00000124171 ENSG00000178184 PMC8467449__F3 Inhibition of Scavenger Receptor Class B Type 1 (SR-B1) Expression and Activity as a Potential Novel Target to Disrupt Cholesterol Availability in Castration-Resistant Prostate Cancer ENSG00000057252 ENSG00000130164 ENSG00000113161 ENSG00000169174 ENSG00000198911 PMC4198363__F5 A role of autophagy in PTP4A3-driven cancer progression ENSG00000291470 ENSG00000198793 ENSG00000284099 ENSG00000057663 PMC7603200__F2 MTOR pathway ENSG00000065911 ENSG00000145979 ENSG00000155792 ENSG00000084774 PMC7286374__F3 Primary pathway of steroidogenesis and enzyme inhibition by posaconazole (P) ENSG00000179142 PMC8505360__AF1 Oleanolic acid blocks the purine salvage pathway for cancer therapy by inactivating SOD1 and stimulating lysosomal proteolysis ENSG00000177169 ENSG00000126775 ENSG00000198793 PMC12211798__F7 Proposed model of IGF2BP3 joined in autophagy mediated TNBC metastasis with m6A-dependent molecular mechanisms ENSG00000198793 PMC7275878__F1 Genetic basis of pneumococcal and staphylococcal infections: inborn errors of human TLR and IL-1R immunity ENSG00000174123 ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000125538 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000090376 ENSG00000184216 PMC3508562__F1 Diagram representing the possible endogenous and exogenous TLR activation pathways and the accompanying response.Abbreviation: TLR, toll-like receptor ENSG00000136869 PMC3508562__F2 Genomics in cardiovascular diseases: analysis of the importance of the toll-like receptor signaling pathway ENSG00000183735 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC11206721__F1 Nutrition-related signaling pathway leading to diabetic nephropathy ENSG00000198793 ENSG00000096717 ENSG00000142082 ENSG00000026103 PMC6241696__F4 Regulatory network of FSH to cervical cancer ENSG00000164305 PMC9576970__F2 Probing predilection to Crohn's disease and Crohn's disease flares: A crowd-sourced bioinformatics approach ENSG00000130300 ENSG00000100033 PMC4127169__F2 Wnts organize presynaptic (CNS and NMJ) and postsynaptic (NMJ) specializations through multiple signaling pathways ENSG00000030304 ENSG00000168036 PMC9576970__F3 Probing predilection to Crohn's disease and Crohn's disease flares: A crowd-sourced bioinformatics approach ENSG00000138075 ENSG00000169248 ENSG00000163739 ENSG00000015520 ENSG00000169429 ENSG00000185591 ENSG00000198911 PMC9404373__F1 Metabolomics in rheumatoid arthritis: Advances and review ENSG00000066468 ENSG00000125538 ENSG00000173599 ENSG00000100985 ENSG00000168610 ENSG00000159399 PMC9576970__F4 Probing predilection to Crohn's disease and Crohn's disease flares: A crowd-sourced bioinformatics approach ENSG00000262406 ENSG00000111537 ENSG00000137673 ENSG00000138079 ENSG00000100906 ENSG00000115415 ENSG00000163739 ENSG00000125538 ENSG00000177606 ENSG00000073756 ENSG00000168610 PMC8119379__F2 De-coding genetic risk variants in type 1 diabetes ENSG00000160185 ENSG00000291603 ENSG00000167207 ENSG00000198053 ENSG00000134982 ENSG00000281879 ENSG00000150637 ENSG00000142166 ENSG00000103811 ENSG00000150782 ENSG00000169245 ENSG00000111537 ENSG00000110395 ENSG00000105397 ENSG00000115415 ENSG00000164342 PMC5226501__F1 Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease ENSG00000150457 ENSG00000131023 PMC6967385__F2 Mouse gene expression affected by biofilm status ENSG00000157184 ENSG00000150991 ENSG00000100979 ENSG00000165269 PMC261890__F8 T Cell Receptor-Independent Basal Signaling via Erk and Abl Kinases Suppresses RAG Gene Expression ENSG00000213658 ENSG00000291971 ENSG00000198793 ENSG00000113263 PMC3583110__F2 Intrinsic and extrinsic apoptotic pathways ENSG00000102871 ENSG00000168040 PMC7086359__F6 Concerted effects of iAs-induced Nrf2 and HIF1A on glycolytic metabolism ENSG00000074800 ENSG00000108515 ENSG00000067057 ENSG00000141086 ENSG00000159399 PMC9144327__F3 Diffuse Intrinsic Pontine Glioma: Molecular Landscape, Evolving Treatment Strategies and Emerging Clinical Trials PMC6862519__F3 Schematic model ENSG00000167580 ENSG00000036828 ENSG00000171885 PMC8080978__F5 Pathways enrichment of Walktrap modules ENSG00000023445 ENSG00000122025 ENSG00000110330 ENSG00000198793 ENSG00000163914 ENSG00000131323 ENSG00000006062 ENSG00000127191 ENSG00000179295 PMC8080978__F3 GO and Pathway enrichments of the PPI network ENSG00000104324 ENSG00000185070 ENSG00000077044 ENSG00000099942 ENSG00000135341 ENSG00000112715 ENSG00000119681 ENSG00000197063 ENSG00000172216 ENSG00000174136 ENSG00000136997 ENSG00000198947 ENSG00000187678 ENSG00000023445 ENSG00000115008 ENSG00000142192 ENSG00000156049 ENSG00000110680 ENSG00000073756 ENSG00000120063 ENSG00000286522 ENSG00000110395 ENSG00000118503 ENSG00000164161 ENSG00000146592 ENSG00000089902 ENSG00000178568 PMC10379484__F2 Endothelin-1 in Health and Disease ENSG00000110799 ENSG00000005893 ENSG00000110651 PMC8080978__F9 Hypothesized mechanism of action of downregulated ERBB4 in SARS-CoV-2 infected cells ENSG00000134982 ENSG00000184012 ENSG00000146648 ENSG00000178568 PMC5880643__F1 Peripheral complement interactions with amyloid B peptide (AB) in Alzheimer’s disease: 1. Erythrocyte clearance of AB ENSG00000244731 ENSG00000182326 ENSG00000236625 PMC8034193__F4 Calcium (or Ca2+) signaling pathway in T ENSG00000124102 ENSG00000130528 ENSG00000110148 ENSG00000156026 ENSG00000186716 ENSG00000143933 PMC9674149__F7 Kyoto encyclopedia of genes and genomes (KEGG) signaling pathway map PMC8081888__F4 Metabolic Landscape for Maintaining Retina Integrity and Function ENSG00000197713 ENSG00000172005 PMC4061475__F1 Dopamine biosynthetic pathway ENSG00000171759 PMC3770583__F7 Rac1/Cdc42 GTPase-Specific Small Molecule Inhibitor Suppresses Growth of Primary Human Prostate Cancer Xenografts and Prolongs Survival in Mice ENSG00000002330 ENSG00000070831 ENSG00000149269 PMC5416929__F8 Working model of TGFB and NFKB pathway interactions that regulate GCT viability PMC4132962__F1 Protective mucosal immunity mediated by epithelial CD1d and IL-10 ENSG00000134982 ENSG00000168610 PMC4001311__F6 Schematics of the regulation of the HMOX1 expression under normal (a and b) and stress conditions (c and d) and without (a and c) or with (b and d) BRD4 knockdown ENSG00000141867 ENSG00000157601 ENSG00000185591 ENSG00000079999 PMC10539950__F2 Innate immune signalling in response to cytosolic DNA and DNA damage ENSG00000104856 ENSG00000149311 ENSG00000169245 ENSG00000183735 ENSG00000164430 ENSG00000163565 ENSG00000175104 ENSG00000115009 PMC3621569__F6 Planar cell polarity pathway (PCP pathway, non-canonical pathway) cascade ENSG00000100592 ENSG00000075275 PMC9254110__F7 FOXF2 oppositely regulates stemness in luminal and basal-like breast cancer cells through the Wnt/beta-catenin pathway ENSG00000137273 ENSG00000171720 ENSG00000186716 ENSG00000157240 PMC3010226__F2 Cellular and molecular scheme for an adaptive immune axis leading to acute lung disease after viral infection ENSG00000184451 ENSG00000126353 ENSG00000291905 ENSG00000106546 PMC5507681__F8 Signaling pathways involved in keratinocyte growth and differentiation that are perturbed by SbIII and AsIII ENSG00000144749 ENSG00000109101 ENSG00000148400 ENSG00000167768 ENSG00000138798 ENSG00000146648 PMC9664671__F1 HOXA9 in solid tumors: mechanistic insights and therapeutic potential ENSG00000177169 ENSG00000078399 ENSG00000198793 ENSG00000169047 ENSG00000177606 ENSG00000168036 ENSG00000171791 ENSG00000145782 ENSG00000159399 PMC7960940__F7 IPA network analysis of differentially expressed proteins in G6PC3 deficiencyIngenuity Pathway Analysis (IPA)-based network 1 of the 148 differentially expressed protein panel ENSG00000211445 ENSG00000065357 ENSG00000173369 ENSG00000285109 ENSG00000198851 ENSG00000107485 ENSG00000166278 ENSG00000182621 ENSG00000073756 ENSG00000254709 ENSG00000105825 PMC7960940__F8 IPA networks analysis of differentially expressed proteins in G6PC3 deficiencyIngenuity Pathway Analysis (IPA)-based network 2 of the 148 differentially expressed protein panel ENSG00000180210 ENSG00000101981 ENSG00000288411 ENSG00000182568 ENSG00000110799 ENSG00000130522 ENSG00000198734 ENSG00000276561 ENSG00000185010 ENSG00000137413 PMC6482478__F1 Basic mechanisms of lithium function ENSG00000128656 ENSG00000197429 PMC7171331__F7 LGR6 KEGG pathway ENSG00000087095 ENSG00000100592 ENSG00000134982 ENSG00000167941 ENSG00000113558 ENSG00000148175 ENSG00000196470 ENSG00000185269 PMC5008685__F2 Mechanisms of initiation of translation ENSG00000163435 ENSG00000128272 ENSG00000120690 ENSG00000144895 ENSG00000100664 PMC5008685__F1 PERK-dependent Unfolded Protein Response ENSG00000128272 ENSG00000144895 PMC12081606__F7 Working model ENSG00000069509 ENSG00000106459 PMC5008685__F4 CHOP-induced apoptosis under prolonged ER stress ENSG00000128272 ENSG00000197930 ENSG00000144895 PMC6008457__F1 Reaction scheme of the metabolic sub-model ENSG00000159224 ENSG00000069482 ENSG00000172005 ENSG00000198670 ENSG00000154016 PMC5866223__F3 Regulation of vascular tone homeostasis by NO and H2S: Implications in hypertension ENSG00000163914 ENSG00000174611 PMC6406535__F1 Contrasting Patterns of Rapid Molecular Evolution within the p53 Network across Mammal and Sauropsid Lineages ENSG00000132906 ENSG00000149212 ENSG00000175793 ENSG00000163743 ENSG00000196470 ENSG00000077463 ENSG00000118971 ENSG00000164305 ENSG00000124762 ENSG00000183765 ENSG00000149311 ENSG00000175054 ENSG00000113328 ENSG00000172667 ENSG00000112378 ENSG00000075218 ENSG00000149554 ENSG00000064012 ENSG00000115107 ENSG00000026103 ENSG00000198625 PMC6083633__F2 Molecular mechanism model for lncRNAs involved in the tumorigenesis of human TNBC ENSG00000113070 ENSG00000138798 ENSG00000165527 ENSG00000136235 ENSG00000146648 PMC6261981__F2 Potential mechanisms involved in propagation of Alpha-syn ENSG00000162711 ENSG00000123091 ENSG00000111537 ENSG00000198793 ENSG00000005381 PMC9633631__F3 Lung fibrosis: Post-COVID-19 complications and evidences ENSG00000137673 ENSG00000134982 ENSG00000157227 ENSG00000168036 PMC6103439__F5 Homeostasis, regeneration and tumour formation in the mammalian epidermis ENSG00000087245 ENSG00000168036 PMC9633631__F4 Lung fibrosis: Post-COVID-19 complications and evidences ENSG00000167601 ENSG00000109321 ENSG00000089685 ENSG00000150457 ENSG00000131023 PMC5069085__F1 Integration of lipid homeostasis into the macrophage host defense response ENSG00000125538 ENSG00000136869 PMC11502746__F6 Selected impacts of MGO exposure in SH-SY5Y cells ENSG00000267855 ENSG00000119723 ENSG00000065518 ENSG00000099624 ENSG00000156467 ENSG00000023909 ENSG00000101365 ENSG00000079999 PMC3416758__F7 TAp73-Mediated the Activation of C-Jun N-Terminal Kinase Enhances Cellular Chemosensitivity to Cisplatin in Ovarian Cancer Cells PMC3148248__F5 TIRAP, an Adaptor Protein for TLR2/4, Transduces a Signal from RAGE Phosphorylated upon Ligand Binding ENSG00000170458 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC8495178__F8 N6-methyladenosine modification regulates ferroptosis through autophagy signaling pathway in hepatic stellate cells ENSG00000101574 PMC6489264__F1 Dauer signalling pathway model proposed for Haemonchus contortus ENSG00000118515 ENSG00000189430 ENSG00000096264 PMC1839891__F1 Systems biology by the rules: hybrid intelligent systems for pathway modeling and discovery ENSG00000128602 PMC2776723__F6 Integration of activated transcription factors with the upstream signaling network during CB1R-induced neurite outgrowth ENSG00000245848 ENSG00000138378 ENSG00000001167 ENSG00000115415 ENSG00000291971 ENSG00000095951 ENSG00000168610 ENSG00000127948 PMC7588666__F1 Base excision repair and its implications to cancer therapy ENSG00000105486 ENSG00000132646 ENSG00000039650 ENSG00000140398 ENSG00000227345 PMC3769628__F2 Four current models of PARP inhibitor-induced cancer cell killing ENSG00000149311 ENSG00000012048 ENSG00000051180 ENSG00000139618 PMC9569475__F5 Hsp90 as a Myokine: Its Association with Systemic Inflammation after Exercise Interventions in Patients with Myositis and Healthy Subjects ENSG00000115415 ENSG00000168610 PMC3621569__F3 Inversin functions as a switch between the canonical Wnt and non-canonical Wnt/PCP pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC7795665__F3 PPARG involved in trophoblast differentiation ENSG00000168036 ENSG00000137270 PMC5086000__F1 Inflammasome Activation Mechanisms during Bacterial Sexually Transmitted Infections (STIs) ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000172936 ENSG00000106100 PMC9261390__F1 Implications of Sphingolipids on Aging and Age-Related Diseases ENSG00000139624 ENSG00000063176 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000143418 PMC8080836__F3 GD T cells ENSG00000139193 ENSG00000150782 ENSG00000291603 ENSG00000111537 ENSG00000163599 ENSG00000143842 ENSG00000125538 ENSG00000168610 PMC12154794__F3 Retinoids and fibrosis ENSG00000142627 ENSG00000105329 PMC9253924__F45 Inhibition of anti-inflammatory pathway through suppressors of cytokine signalling (Socs2/Socs3) in the initiation of hepatocellular carcinoma ENSG00000120833 ENSG00000111057 ENSG00000140505 ENSG00000130649 ENSG00000172936 ENSG00000140465 PMC7521313__F7 Mechanism of danshen on heart failure is mediated by MyD88‐dependent TLR4‐TRAF6‐NF‐KB inflammation pathway’ ENSG00000173039 ENSG00000136869 ENSG00000175104 PMC10242999__F2 Tissue factor (coagulation factor III): a potential double-edge molecule to be targeted and re-targeted toward cancer ENSG00000070831 ENSG00000291971 PMC3849481__F6 Schematic diagram showing CSFV triggers RIG-I and MDA5 dependent signaling pathway to IRF-3 and NFKB activation to promote the production of antiviral and inflammatory cytokines in porcine alveolar macrophages ENSG00000183735 ENSG00000125538 PMC4278548__F1 Central metabolic routes and the aromatic compounds biosynthesis showing key metabolites and the genes involved in their transformation ENSG00000108849 ENSG00000127837 ENSG00000122966 ENSG00000172005 PMC10242999__F3 Tissue factor (coagulation factor III): a potential double-edge molecule to be targeted and re-targeted toward cancer ENSG00000117525 ENSG00000138798 ENSG00000198793 ENSG00000168036 PMC5466514__F1 Cancer cells take advantage and manipulate the ROS-Ca2+ interplay in two ways: 1) by inhibiting large ROS-Ca2+ surges that mediate apoptosis (red pathway) ENSG00000175938 ENSG00000144935 ENSG00000167323 ENSG00000293604 ENSG00000156026 ENSG00000137672 ENSG00000196689 PMC5510801__F1 Extracellular inhibitors can attenuate tumorigenic Wnt pathway activity in adenomatous polyposis coli mutants: Predictions of a validated mathematical model ENSG00000134982 ENSG00000168036 ENSG00000104332 PMC7521313__F3 Danshen is shown to regulate the TLR signalling pathway ENSG00000169245 ENSG00000239732 ENSG00000118785 ENSG00000170458 ENSG00000113520 ENSG00000136869 ENSG00000168040 ENSG00000150455 ENSG00000171608 ENSG00000111816 ENSG00000143387 PMC4085163__F6 Schematic models of signalling pathways used by SDF-1/CXCR4 and GLP-1/GLP-1R in the activation of beta catenin/TCF7L2-mediated transcriptional expression of genes involved in beta cell survival and proliferation a SDF-1 activation of WNT signalling ENSG00000134982 ENSG00000121966 PMC7467536__F2 PRC2-mediated feed-forward control of transcription factors and signaling pathway components can serve as a “dimmer switch” of gene expression changes ENSG00000126231 ENSG00000105664 PMC9600545__F4 Exosomal Plasma Gelsolin Is an Immunosuppressive Mediator in the Ovarian Tumor Microenvironment and a Determinant of Chemoresistance ENSG00000111537 ENSG00000115415 ENSG00000027697 ENSG00000113520 PMC12235416__F1 (Figure created using BioRender ENSG00000283780 ENSG00000137845 PMC5352108__F1 Long non-coding RNAs in anti-cancer drug resistance ENSG00000168036 PMC7000272__F1 RELA interactome ENSG00000104856 ENSG00000167207 ENSG00000109320 ENSG00000173039 ENSG00000168036 ENSG00000171791 ENSG00000112715 ENSG00000166851 ENSG00000163435 ENSG00000077150 ENSG00000125398 ENSG00000074181 ENSG00000122691 ENSG00000284099 ENSG00000169429 ENSG00000083799 ENSG00000064012 PMC8834144__F8 Comparative Transcriptomic Profiles of Differentiated Adipocytes Provide Insights into Adipogenesis Mechanisms of Subcutaneous and Intramuscular Fat Tissues in Pigs ENSG00000145632 ENSG00000065911 ENSG00000185015 ENSG00000077044 ENSG00000139629 ENSG00000169231 ENSG00000026103 PMC7072933__F1 Activation of mTOR Signaling Pathway in Hepatocellular Carcinoma ENSG00000198793 PMC9485270__F5 Melanoma: Molecular genetics, metastasis, targeted therapies, immunotherapies, and therapeutic resistance ENSG00000157764 ENSG00000111859 ENSG00000136997 ENSG00000164362 ENSG00000168036 PMC11084446__F8 Brief diagram of the proposed therapeutic effect of the LiESWT in improving detrusor hyperactivity via TRPV channels and the cellular signaling pathway involved in regulating intracellular Ca2+ oscillation in a rat model of OHD-induced DHIC ENSG00000196689 PMC5055575__F9 The signalling pathways mediating PTH and BMP-2 induced regulation of Phospho1, Smpd3 and Alpl in osteoblast cells ENSG00000107779 ENSG00000152266 ENSG00000162551 ENSG00000163295 ENSG00000173868 PMC8631470__F1 Cross-Talk Between Tumor Cells Undergoing Epithelial to Mesenchymal Transition and Natural Killer Cells in Tumor Microenvironment in Colorectal Cancer ENSG00000181847 ENSG00000132646 ENSG00000189403 ENSG00000109943 ENSG00000182985 ENSG00000231179 ENSG00000204520 PMC5833552__F1 Regulatory B cells: the cutting edge of immune tolerance in kidney transplantation ENSG00000239732 ENSG00000186716 ENSG00000125538 ENSG00000136869 PMC7467536__F1 PRC2 core and accessory proteins and downstream effects ENSG00000151376 ENSG00000065833 ENSG00000139154 ENSG00000273604 ENSG00000082212 PMC3218884__F4 Signalling network of proteins identified as major targets of autoantibodies in patients with unidentified ANA ENSG00000160789 ENSG00000119608 ENSG00000196591 ENSG00000088247 ENSG00000162521 ENSG00000124795 ENSG00000139687 PMC11772333__F5 Biosynthetic pathway of three representative pyrroles ENSG00000144410 ENSG00000135845 ENSG00000126088 ENSG00000170430 ENSG00000188690 ENSG00000127948 PMC4512304__F2 Ramification of IFN signaling pathways leading to immunostimulatory and immunosuppressive regulation of macrophage polarization ENSG00000213928 ENSG00000105397 ENSG00000138755 ENSG00000157601 ENSG00000125347 ENSG00000142166 PMC7374916__F10 Schematic illustration of the proposed mechanism for H2R/H3R to alleviate microglia-induced neuroinflammation ENSG00000150907 ENSG00000125538 ENSG00000136869 PMC5527800__F3 Ingenuity pathway analysis ENSG00000019991 ENSG00000042832 ENSG00000105329 ENSG00000130522 ENSG00000169047 ENSG00000168036 ENSG00000127528 ENSG00000104921 ENSG00000104368 ENSG00000011422 ENSG00000196549 ENSG00000157227 ENSG00000149968 ENSG00000136997 ENSG00000188404 ENSG00000149418 ENSG00000154096 ENSG00000148346 ENSG00000087245 ENSG00000099985 ENSG00000100448 ENSG00000131910 ENSG00000173402 ENSG00000069482 ENSG00000134013 ENSG00000157766 ENSG00000026508 ENSG00000151617 PMC6534900__F3 Summary of the regulation network of Ids in heart development is shown ENSG00000107779 ENSG00000154342 ENSG00000170365 ENSG00000166823 ENSG00000285109 ENSG00000128052 ENSG00000135503 ENSG00000089225 ENSG00000016082 PMC11647257__SF2 Various signaling molecules, such as glucocorticoids, androgens, progesterone, BMP4 (which activates SMAD), and IL-6 (which activates the downstream signaling molecule STAT3), regulate the transcriptional activity of S100P in cancer cells ENSG00000116161 ENSG00000163993 ENSG00000168610 PMC5062963__F7 Comparative model of transcriptional activation of ERA by cognate ligand versus cAMP signaling in the absence of estrogen ENSG00000094631 ENSG00000084093 ENSG00000142453 ENSG00000155974 PMC4254647__F3 FA/BRCA DNA damage response pathway ENSG00000136492 ENSG00000083093 ENSG00000077152 ENSG00000108384 ENSG00000162607 ENSG00000139618 PMC6994583__F1 Pathways of H2S production ENSG00000205221 PMC8065809__F10 Postulated model for the mechanism underlying IGF-Trap resistance in MDA-MB-231 ENSG00000077782 PMC9458025__F3 Functional Annotation of Lactiplantibacillus plantarum 13-3 as a Potential Starter Probiotic Involved in the Food Safety of Fermented Products ENSG00000169291 ENSG00000015285 ENSG00000047597 ENSG00000163631 PMC2872188__F2 Generalized depiction of the energy cost of neurovascular coupling and its impact on astrocytic glucose utilization (CMRglc) ENSG00000166278 ENSG00000137055 PMC3305403__F4 The Nucleoside Diphosphate Kinase Gene Nme3 Acts as Quantitative Trait Locus Promoting Non-Mendelian Inheritance ENSG00000163914 ENSG00000103024 ENSG00000146192 PMC6631168__F1 The Role of Wnt and R-spondin in the Stomach During Health and Disease ENSG00000281324 ENSG00000125398 ENSG00000162337 ENSG00000134982 ENSG00000133067 ENSG00000183579 ENSG00000108375 PMC9205222__F2 Molecular Approaches Reduce Saturates and Eliminate trans Fats in Food Oils ENSG00000198670 ENSG00000026103 PMC8529064__F5 Microbiota in Infant Health: From Early Life to Adulthood ENSG00000145365 ENSG00000175104 PMC2750148__F2 NFKB signal transduction ENSG00000150991 ENSG00000172936 ENSG00000175104 PMC4959106__F1 De novo SL biosynthesis and S1P metabolism ENSG00000063176 ENSG00000170989 ENSG00000183018 PMC5466881__F1 Strategies for Increasing Pancreatic Tumor Immunogenicity ENSG00000108691 ENSG00000164949 PMC11177172__F5 Regulatory associations between protein-protein networks, based on the IPA Knowledge Base ENSG00000124614 ENSG00000134419 ENSG00000115268 ENSG00000173674 ENSG00000189403 ENSG00000278270 ENSG00000121060 ENSG00000112306 ENSG00000166228 ENSG00000143742 PMC4959106__F3 Nogo-B regulates de novo SL biosynthesis through the inhibition of SPT activity to control vascular tone and BP ENSG00000170989 ENSG00000267534 ENSG00000183018 PMC8533259__F3 Coordination of RNA Processing Regulation by Signal Transduction Pathways ENSG00000175054 PMC7346062__F5 KEGG pathways related to resveratrol-targeted genes ENSG00000117020 PMC4401777__F7 Loregic: A Method to Characterize the Cooperative Logic of Regulatory Factors ENSG00000030582 ENSG00000001167 ENSG00000196591 ENSG00000185591 ENSG00000179348 PMC8154354__F2 Insights into Ammonia Adaptation and Methanogenic Precursor Oxidation by Genome-Centric Analysis ENSG00000145020 ENSG00000127948 ENSG00000116984 PMC2246131__F7 Schematic diagram showing the possible effects of the reelin pathway in protection from CM ENSG00000291971 ENSG00000189056 ENSG00000173406 PMC5988607__F1 Signaling network of MST1 and MST2 kinase ENSG00000114978 ENSG00000150457 ENSG00000131023 PMC5727869__F10 The function mechanism of HER2-HER3 co-expression ENSG00000198793 ENSG00000168610 PMC9033932__F3 Targeting TGFB signal transduction for fibrosis and cancer therapy ENSG00000171621 PMC4214731__F8 Network-Based Classification Model for Deriving Novel Drug-Disease Associations and Assessing Their Molecular Actions ENSG00000150907 ENSG00000115904 ENSG00000175899 ENSG00000124181 ENSG00000168610 ENSG00000148824 ENSG00000132170 ENSG00000179295 PMC4909545__F1 Nutrient-sensing mTORC1: integration of metabolic and autophagic signals ENSG00000101407 ENSG00000110497 ENSG00000123395 ENSG00000155792 ENSG00000112561 PMC11803499__F2 B cell signaling is integrated downstream of activating receptors to regulated B cell‐specific cellular functions and B cell fate decisions ENSG00000104856 ENSG00000105369 ENSG00000007312 ENSG00000198793 ENSG00000155792 ENSG00000173039 ENSG00000164327 ENSG00000127191 ENSG00000010671 ENSG00000177455 ENSG00000239732 ENSG00000186716 ENSG00000172936 ENSG00000131323 ENSG00000175104 PMC5024535__F6 Hypermutation of DPYD Deregulates Pyrimidine Metabolism and Promotes Malignant Progression ENSG00000188641 ENSG00000179958 ENSG00000158825 ENSG00000147647 PMC10707303__F5 Fibrotic factors in the development of DKD ENSG00000087245 ENSG00000115415 PMC11803499__F4 Inhibitory receptors modulate the PI3K/AKT/mTOR pathway to influence B cell fate decisions ENSG00000186716 ENSG00000155792 ENSG00000164327 ENSG00000026103 PMC4640679__F5 Non-biased molecular screening identifies novel molecular regulators of fibrogenic and proliferative signaling in myxomatous mitral valve disease ENSG00000019991 ENSG00000087245 ENSG00000168329 ENSG00000142178 ENSG00000150337 ENSG00000102678 ENSG00000196628 ENSG00000156103 ENSG00000170458 ENSG00000177606 ENSG00000136997 ENSG00000125810 ENSG00000183864 ENSG00000112149 ENSG00000177283 ENSG00000104432 ENSG00000164342 PMC4633932__F2 Nutrient, growth factor, and energy sensing impinge on the mTOR pathway ENSG00000198793 ENSG00000164327 PMC5512170__F3 Barcoding of GPCR Trafficking and Signaling Through the Various Trafficking Roadmaps by Compartmentalized Signaling Networks ENSG00000119321 ENSG00000143376 ENSG00000111237 ENSG00000069329 PMC2975092__F6 Biological interaction between glucose and genes up- (light grey) or down-regulated (white) in primary hepatic stellate cells after overexpression of Smad7 ENSG00000019991 ENSG00000067057 ENSG00000175745 ENSG00000130649 ENSG00000112715 ENSG00000187840 ENSG00000159399 PMC6441107__F7 Proposed diagram for miRs-449 regulation in doxorubicin sensitivity and resistance cells ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000139687 ENSG00000175305 PMC7334005__F6 Transcriptional Control of Circadian Rhythms and Metabolism: A Matter of Time and Space ENSG00000147162 ENSG00000105835 ENSG00000171720 ENSG00000196591 ENSG00000132326 ENSG00000096717 PMC11663674__F1 Isolation, bioactivity, and synthesis of natural products from Litsea verticillate with anti-HIV activities ENSG00000108849 ENSG00000065833 ENSG00000119929 ENSG00000198125 PMC6796923__F4 LSECtin-BTN3A3 axis promotes breast cancer stemness in vitro ENSG00000111801 PMC4809656__F8 Molecular mechanisms by corilagin suppresses cholangiocarcinoma progression through Notch signaling pathway ENSG00000283780 ENSG00000148400 ENSG00000198793 ENSG00000114315 PMC8901598__F2 Metabolic and Epigenetic Regulation by Estrogen in Adipocytes ENSG00000157554 ENSG00000127663 ENSG00000139372 ENSG00000132170 PMC2637898__F2 EGFR signaling pathways ENSG00000198793 PMC2637898__F3 EGFR signal transduction pathways ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000146648 PMC2637898__F4 VEGF signaling pathways ENSG00000118257 ENSG00000150630 PMC6829200__F1 Components and regulatory factors in the complement alternative pathway (CAP) ENSG00000000971 ENSG00000062485 PMC4663505__F7 Drug target prioritization by perturbed gene expression and network information ENSG00000162552 ENSG00000143878 ENSG00000109320 ENSG00000148926 ENSG00000160181 ENSG00000148344 ENSG00000184916 ENSG00000073756 ENSG00000136826 ENSG00000132170 ENSG00000164056 ENSG00000139725 ENSG00000177606 ENSG00000136997 ENSG00000146648 PMC5298971__F1 Vitamin D synthesis pathway ENSG00000111012 ENSG00000205221 ENSG00000019186 ENSG00000186104 ENSG00000135929 PMC3772119__F1 Drosophila JAK-STAT pathway in blood cell formation and immunity ENSG00000291507 ENSG00000213658 PMC2763507__F1 Bipolar disorder: involvement of signaling cascades and AMPA receptor trafficking at synapses ENSG00000002330 ENSG00000130522 ENSG00000168036 PMC4344844__F2 Wnt and FGF mediated epithelial mesenchymal crosstalk during lung development ENSG00000198793 ENSG00000168036 PMC6759464__F1 Abbreviated summary of monocyte activation pathways ENSG00000275385 ENSG00000136869 ENSG00000132693 PMC8996539__F4 Neutrophil degranulation and myocardial infarction ENSG00000087245 ENSG00000135218 ENSG00000137673 ENSG00000149968 ENSG00000100985 ENSG00000122194 PMC7564943__F6 AhR-induced cyclooxygenase (COX) 2/PGE2/EP4 has differential effects in anti-viral cells vs ENSG00000106546 PMC11079401__F2 MiRNAs in EMT regulation via TGFB signaling pathway in pancreatic tumor cells ENSG00000158050 PMC11079401__F3 MiRNAs in EMT regulation via PI3K/AKT signaling pathway in pancreatic tumor cells ENSG00000138772 ENSG00000198793 ENSG00000117139 ENSG00000163993 PMC7564943__F3 AhR activation contributes to alterations in mitochondrial metabolism as does suppressed pineal melatonin ENSG00000106546 PMC10670414__F8 Anticancer Effects of 6-Gingerol through Downregulating Iron Transport and PD-L1 Expression in Non-Small Cell Lung Cancer Cells ENSG00000173757 ENSG00000146648 ENSG00000115107 PMC11079401__F4 MiRNAs in EMT regulation via WNT and JAK/STAT signaling pathways in pancreatic tumor cells ENSG00000007341 ENSG00000281324 ENSG00000162337 ENSG00000171150 ENSG00000134982 ENSG00000168036 PMC8841354__F5 Interleukins and Ischemic Stroke ENSG00000150782 ENSG00000137033 ENSG00000125538 ENSG00000142224 PMC6066316__F8 Differentiation of monocytes promotes resistance to ripoptosome signaling ENSG00000137275 ENSG00000136869 ENSG00000168404 ENSG00000285379 ENSG00000142166 PMC8001593__F3 Host-catalyzed HIV-1 assembly pathway was developed into a screen for small molecule inhibitors ENSG00000114127 PMC5683051__F1 Interconnection between endoplasmic reticulum (ER) stress/unfolded protein response (UPR) pathways and mitochondria-NLRP3 inflammasome in allergic diseases ENSG00000162711 ENSG00000128272 ENSG00000144895 ENSG00000125538 PMC8431527__F1 Hypoxia Pathway Proteins and Their Impact on the Blood Vasculature ENSG00000134086 ENSG00000111653 ENSG00000020633 ENSG00000118520 ENSG00000144791 ENSG00000168610 PMC4344844__F3 Wnt and FGF mediated epithelial mesenchymal crosstalk during lung development ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11900433__F9 Phosphoinositide 3-kinase (PI3K)/Akt pathway ENSG00000198793 PMC11904867__F2 Nur77 in glucose metabolism ENSG00000074800 ENSG00000108515 ENSG00000198793 ENSG00000087842 ENSG00000164708 PMC9515456__F4 Sneaking into the viral safe-houses: Implications of host components in regulating integrity and dynamics of rotaviral replication factories ENSG00000144895 ENSG00000284850 ENSG00000100219 ENSG00000272886 ENSG00000123908 PMC11900433__F8 MAPK/AP-1 signaling pathway ENSG00000162889 ENSG00000089022 ENSG00000114738 PMC7940537__F1 MTORC1 signaling and glycolysis pathways ENSG00000198793 ENSG00000155792 PMC11900433__F5 NRF2–ARE pathway ENSG00000100387 ENSG00000079999 PMC5009750__F1 NFKB pathway genes with correlation to HOXA1 expression in breast cancer ENSG00000107562 ENSG00000291603 ENSG00000125735 ENSG00000102871 ENSG00000111321 ENSG00000171791 ENSG00000150455 ENSG00000095585 ENSG00000077150 ENSG00000213658 ENSG00000166501 ENSG00000124181 ENSG00000081041 ENSG00000154589 ENSG00000242689 ENSG00000109320 ENSG00000127191 ENSG00000073756 ENSG00000149311 ENSG00000226275 ENSG00000170458 ENSG00000102245 ENSG00000186716 ENSG00000131323 ENSG00000175104 ENSG00000121060 PMC6531411__F1 Diversity of the effects of DJ-1 in cell ENSG00000197579 ENSG00000079999 PMC5384354__F9 Proliferation by crosstalk of miR-204 and miR-17/92 in smooth muscle cells ENSG00000291971 ENSG00000171759 ENSG00000168610 PMC7481292__F5 Summary of effects of TCDD on OCM gene expression and metabolites PMC8430083__F5 Comprehensive network analysis of different subtypes of molecular disorders in lung cancer ENSG00000145604 ENSG00000105664 ENSG00000108691 ENSG00000041982 ENSG00000005381 ENSG00000108821 ENSG00000010671 PMC4593320__F2 Role of Bmi-1 in Ink4a/Arf Pathway ENSG00000198901 ENSG00000135446 PMC8066025__F2 Indirect antiviral activities of PARPs through immunomodulation ENSG00000111537 ENSG00000163840 ENSG00000059378 ENSG00000178685 ENSG00000111224 PMC10310985__F4 DEAD-box RNA helicases with special reference to p68: Unwinding their biology, versatility, and therapeutic opportunity in cancer ENSG00000134982 ENSG00000198793 ENSG00000127191 ENSG00000168610 ENSG00000146648 PMC6503977__F7 Proposed Shh-Foxd1-Cdkn1c signaling model ENSG00000129757 ENSG00000135446 ENSG00000164690 ENSG00000128602 ENSG00000251493 PMC6892507__F5 Gene expression is associated with virulence in murine macrophages infected with Leptospira spp ENSG00000149311 PMC2871799__F6 Human endometrial receptivity ENSG00000180210 ENSG00000166086 ENSG00000291559 ENSG00000134363 ENSG00000166278 ENSG00000168398 ENSG00000198125 ENSG00000115718 ENSG00000122194 ENSG00000276838 ENSG00000184500 PMC11937194__F5 Related mechanisms of TRPC1, TRPM7, CLCA2, CLCA4, and TTYH3 in the process of EMT ENSG00000092439 ENSG00000144935 ENSG00000136295 ENSG00000016602 ENSG00000170558 PMC11937194__F6 Related mechanisms of TRPV1, TRPM8, Orai1and KCa3 ENSG00000293604 ENSG00000196689 PMC11937194__F7 Related mechanisms of TRPC3, TRPV1, L-VGCC, A2D1 and TTYH3 in regulating tumor stemness ENSG00000087245 ENSG00000136295 ENSG00000138741 ENSG00000196689 PMC8170311__F1 Metabolism in the Development of Personalized Therapies in Acute Myeloid Leukemia ENSG00000122025 ENSG00000135218 ENSG00000181163 ENSG00000103257 PMC11937194__F4 Related mechanisms of TRPV3, TRPV4, and Orai1 in tumor angiogenesis ENSG00000293604 PMC9457814__F2 Prostate Cancer Review: Genetics, Diagnosis, Treatment Options, and Alternative Approaches ENSG00000198793 PMC8172474__F1 Therapeutic Escape in GAq-Mutant Uveal Melanoma: It’s a FAK ENSG00000038382 ENSG00000163930 ENSG00000089692 ENSG00000163914 PMC7585948__F10 Targeting feed-forward signaling of TGFB/NOX4/DHFR/eNOS uncoupling/TGFB axis with anti-TGFB and folic acid attenuates formation of aortic aneurysms ENSG00000228716 ENSG00000086991 PMC3882126__F1 Autism genes keep turning up chromatin ENSG00000198793 ENSG00000139613 ENSG00000049618 ENSG00000100888 ENSG00000179915 ENSG00000292254 PMC5359687__F1 Heterogeneity in Cancer Metabolism: New Concepts in an Old Field ENSG00000065833 ENSG00000169710 ENSG00000135069 ENSG00000115419 PMC8524664__F10 Protective effects of safranal on hypoxia/reoxygenation-induced injury in H9c2 cardiac myoblasts via the PI3K/AKT/GSK3B signaling pathway PMC5359687__F6 Heterogeneity in Cancer Metabolism: New Concepts in an Old Field ENSG00000107562 ENSG00000198793 ENSG00000049768 PMC10380285__F1 Influence of Single Nucleotide Polymorphisms on Vitamin D Receptor Protein Levels and Function in Chronic Liver Disease ENSG00000291971 ENSG00000185591 PMC8727779__F3 Strategies to overcome drug resistance using SHP2 inhibitors ENSG00000291971 ENSG00000138798 PMC3939323__F3 A, JAK-STAT signaling pathway in interaction network ENSG00000110395 ENSG00000137193 PMC9377404__F8 Vitamin B6 Metabolic Pathway is Involved in the Pathogenesis of Liver Diseases via Multi-Omics Analysis ENSG00000109814 ENSG00000150782 ENSG00000140263 ENSG00000198074 ENSG00000135069 ENSG00000166278 ENSG00000093217 ENSG00000169919 ENSG00000127948 ENSG00000138356 PMC8196896__F3 Transmembrane TNF and Its Receptors TNFR1 and TNFR2 in Mycobacterial Infections ENSG00000056558 ENSG00000127191 PMC8196896__F2 Transmembrane TNF and Its Receptors TNFR1 and TNFR2 in Mycobacterial Infections ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000285379 PMC8923098__F1 Reversing epigenetic repression of transposable elements for improving tumor immunogenicity ENSG00000164430 ENSG00000088888 ENSG00000143379 PMC5189614__F1 Cellular control of hyperglycemia ENSG00000138798 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC4701041__F7 Proposed model for a critical role of ERA in E2-induced cholesterol gallstones ENSG00000005471 ENSG00000138075 ENSG00000130164 ENSG00000073734 PMC3434475__F1 The canonical translation pathway in eukaryotes with the ribosomal recycling and initiation phases shown in detail ENSG00000163435 ENSG00000120690 ENSG00000100664 ENSG00000164163 PMC10993426__F2 Metabolites, metabolic pathways and related metabolic genes that take part in necrosis and necroptosis ENSG00000124256 ENSG00000023734 ENSG00000128272 ENSG00000168404 PMC2930269__F2 CSCs drug resistance methodology ENSG00000170430 ENSG00000118777 PMC10993426__F3 Metabolites, metabolic pathways and related metabolic genes that play the roles in ferroptosis ENSG00000163930 ENSG00000151012 ENSG00000167468 PMC7520711__F1 Major regulators and effectors of the phosphatidylinositol 3-kinase (PI3K) pathway in lymphocytes ENSG00000177455 ENSG00000124102 ENSG00000109452 ENSG00000186716 ENSG00000198793 ENSG00000100100 PMC10993426__F1 Metabolites, metabolic pathways and related metabolic genes that play the roles in apoptosis ENSG00000131473 ENSG00000105835 ENSG00000102871 ENSG00000198793 ENSG00000175832 ENSG00000099194 ENSG00000120868 ENSG00000078237 ENSG00000168040 PMC10993426__F7 Metabolites, metabolic pathways and related metabolic genes that work in autophagy ENSG00000096717 PMC10993426__F4 Metabolites, metabolic pathways and related metabolic genes that play the roles in pyroptosis ENSG00000278718 ENSG00000162711 ENSG00000150782 ENSG00000130164 ENSG00000167468 PMC11647257__SF6 CNN1 signaling pathway involved in cancer ENSG00000087245 ENSG00000198793 ENSG00000168036 ENSG00000100985 PMC8236857__F2 Biological Role of MYCN in Medulloblastoma: Novel Therapeutic Opportunities and Challenges Ahead ENSG00000261857 ENSG00000136997 PMC8236857__F3 Biological Role of MYCN in Medulloblastoma: Novel Therapeutic Opportunities and Challenges Ahead ENSG00000142627 ENSG00000123496 ENSG00000113161 ENSG00000169710 PMC4509978__F2 CMV-induced embryonic mouse organ of Corti dysplasia: network architecture of dysfunctional lateral inhibition ENSG00000135547 ENSG00000148400 ENSG00000132646 ENSG00000117707 ENSG00000273529 ENSG00000184916 ENSG00000172238 PMC10875085__F2 Mechanisms for E protein-induced lung injury ENSG00000162711 ENSG00000172936 ENSG00000072415 PMC11725633__F2 Immunoregulation of CD4+ and CD8+ T cells by fatty acids ENSG00000131473 ENSG00000185813 ENSG00000169710 ENSG00000107485 ENSG00000073754 ENSG00000049768 PMC5898978__F1 Prostaglandin E2 as a Regulator of Immunity to Pathogens ENSG00000226275 PMC11725633__F1 Fatty acid metabolism in T cells ENSG00000135218 ENSG00000126266 ENSG00000169710 ENSG00000198670 PMC7775286__F1 Diagram of NK cell receptor signaling: ENSG00000291603 ENSG00000213658 ENSG00000010810 ENSG00000141968 PMC7157668__F1 Mycobacterium evades macrophage apoptosis by induction of anti-apoptotic cytokines and miRNAs expression ENSG00000002330 ENSG00000105397 ENSG00000105246 ENSG00000171791 ENSG00000168040 ENSG00000168610 ENSG00000105373 ENSG00000076604 ENSG00000026103 PMC7734804__F1 Initial establishment of anti-viral state via innate immune responses to DENV infection ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 PMC10452836__F7 Reconstructed network using StringDB of the dynamic interactome of KRASG12C (grey halo) in HEK293 cells identified in the AP-MS screen ENSG00000157927 ENSG00000142279 PMC10875085__F1 Mechanisms for S protein-induced lung injury ENSG00000162711 ENSG00000130234 ENSG00000136869 ENSG00000168610 PMC3703753__F2 Impact of Subarachnoid Hemorrhage on Parenchymal Arteriolar Function ENSG00000113070 ENSG00000146648 ENSG00000174611 PMC10879484__F7 Predicted activation of macrophage classical activation signaling pathway in parenteral nutrition piglets ENSG00000153208 ENSG00000111537 ENSG00000170458 ENSG00000173039 ENSG00000136869 ENSG00000125347 ENSG00000115009 PMC10879484__F8 Therapeutics identified as strongly inhibited upstream regulators in Ingenuity Pathway Analysis ENSG00000213928 ENSG00000005339 ENSG00000177606 ENSG00000125686 PMC3083951__F3 A model (steps 1-4) for copper homeostasis in Schizosaccharomyces pombe (Schiz ENSG00000138495 ENSG00000166260 ENSG00000133028 PMC4550399__F8 Temporal Gene Expression of the Cyanobacterium Arthrospira in Response to Gamma Rays ENSG00000039537 ENSG00000226492 PMC5045492__F2 Depiction of the organization of the major steroid biosynthetic pathways in the adrenal cortex ENSG00000108582 ENSG00000127948 PMC5012644__F2 Hypoxia-inducible transcription factor (HIF) pathway in clear cell renal cancer ENSG00000163930 ENSG00000163939 ENSG00000134086 ENSG00000181555 ENSG00000154582 PMC2646147__F6 A model for three pathways of TLS in mammalian cells ENSG00000108582 ENSG00000130997 ENSG00000122008 PMC7103649__F9 Significant correlations between HSD17B4, ACAA1, and PXMP4 expressions and immunomodulator gene expressions ENSG00000134460 ENSG00000107562 ENSG00000111981 ENSG00000105329 ENSG00000125735 ENSG00000048462 ENSG00000163599 ENSG00000232326 ENSG00000134061 ENSG00000168961 ENSG00000121966 ENSG00000161955 ENSG00000167664 ENSG00000114455 ENSG00000181847 ENSG00000128052 ENSG00000158825 ENSG00000213809 ENSG00000139193 ENSG00000133835 ENSG00000284100 ENSG00000273686 ENSG00000231179 ENSG00000231925 ENSG00000273936 ENSG00000215788 ENSG00000188389 ENSG00000186827 ENSG00000135077 ENSG00000226275 ENSG00000224320 ENSG00000134545 ENSG00000101417 ENSG00000049249 PMC4718075__F2 Adipocytokines and Hepatic Fibrosis ENSG00000157500 ENSG00000168610 PMC6104113__F7 Simplified schematic showing the potential strategy for muscle‐derived miR‐23a/27a to attenuate muscle atrophy and renal fibrosis PMC9588789__F7 Schema depicting the BET inhibitor resistance in PCa cells due to RB loss and hyperphosphorylation ENSG00000141867 ENSG00000135446 ENSG00000185838 ENSG00000105810 PMC9576946__F1 Neglected, yet significant role of FOXP1 in T-cell quiescence, differentiation and exhaustion ENSG00000132646 ENSG00000198793 ENSG00000100100 PMC3297025__F1 IL-1 signaling leads to actin stress fiber formation ENSG00000163914 ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC3297025__F2 BTB restructuring and spermiation are coordinated by IL-1A during spermatogenesis ENSG00000172936 ENSG00000184216 PMC9140926__F10 Prunetinoside Inhibits Lipopolysaccharide-Provoked Inflammatory Response via Suppressing NFKB and Activating the JNK-Mediated Signaling Pathway in RAW264.7 Macrophage Cells ENSG00000125538 PMC9240468__F5 MIR4435-2HG Is a Potential Pan-Cancer Biomarker for Diagnosis and Prognosis ENSG00000065978 ENSG00000134982 ENSG00000111728 ENSG00000168036 ENSG00000205250 ENSG00000150457 ENSG00000155760 ENSG00000131023 PMC4012311__F11 Regulation of TRN mechanosensation ENSG00000124102 PMC5429979__F2 Glutamine/glutamate utilization in proliferating cells ENSG00000168003 ENSG00000125166 ENSG00000065833 ENSG00000143158 ENSG00000004864 ENSG00000135069 ENSG00000103257 ENSG00000166123 ENSG00000105552 ENSG00000115419 ENSG00000060762 ENSG00000167701 PMC5429979__F3 Serine/glycine metabolism in proliferating cells ENSG00000284320 ENSG00000228716 ENSG00000065911 ENSG00000100714 ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC8264290__F1 Computational Approach Identified Andrographolide as a Potential Drug for Suppressing COVID-19-Induced Cytokine Storm ENSG00000167207 ENSG00000078747 ENSG00000177606 ENSG00000007908 ENSG00000166278 ENSG00000131323 ENSG00000168040 ENSG00000168404 ENSG00000127191 PMC4633493__F1 Mechanisms through which microRNAs (miRNAs) implicated in the TGFB signaling pathway in the lung epithelial cells and fibroblasts ENSG00000168610 PMC6581552__F2 Understanding Bile Acid Signaling in Diabetes: From Pathophysiology to Therapeutic Targets ENSG00000160867 ENSG00000105550 ENSG00000180432 ENSG00000135929 PMC3578987__F2 MITOCHONDRIAL GLUTATHIONE: FEATURES, REGULATION AND ROLE IN DISEASE ENSG00000188690 ENSG00000026103 PMC6886551__F4 Protein–protein interaction network of the differentially expressed proteins between IH-exposed HUVECs treated with or without estradiol (E2) ENSG00000169925 ENSG00000088682 ENSG00000198793 ENSG00000196591 ENSG00000070669 ENSG00000179295 ENSG00000115464 ENSG00000181090 ENSG00000162923 ENSG00000123545 ENSG00000288146 ENSG00000106009 ENSG00000100347 ENSG00000101413 ENSG00000141759 ENSG00000101138 ENSG00000161542 ENSG00000163125 ENSG00000136522 ENSG00000103642 ENSG00000163875 ENSG00000281877 ENSG00000173402 ENSG00000149311 ENSG00000120805 ENSG00000213965 ENSG00000170855 ENSG00000162851 ENSG00000166123 PMC6002380__F4 NOD-like receptor signaling pathway ENSG00000108691 ENSG00000167207 ENSG00000187796 ENSG00000157625 ENSG00000087077 PMC7582305__F6 Downstream signaling cascade activated by ATR and ATM via CHK1/2 dependent phosphorylation events PMC10686798__F1 Wnt/Bcatenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC10995981__F2 CircRNAs play a pivotal role in the advancement of esophageal cancer by modulating the Wnt pathway through diverse mechanisms ENSG00000078747 ENSG00000104290 ENSG00000124766 ENSG00000168036 ENSG00000271303 PMC10995981__F3 circRNAs play a pivotal role in the initiation and progression of liver cancer by regulating the Wnt pathway through diverse mechanisms ENSG00000182010 ENSG00000112242 ENSG00000134982 ENSG00000152977 ENSG00000050165 ENSG00000168036 PMC6481643__F10 Novel IL-1Beta-ILC3-IL-2 circuit is essential for the maintenance of Tregs and immunologic homeostasis uniquely within the small intestine ENSG00000167207 ENSG00000125538 ENSG00000172936 ENSG00000049768 PMC3493339__F4 STRING Network ENSG00000150991 ENSG00000110395 ENSG00000115415 ENSG00000163235 ENSG00000291971 ENSG00000124882 ENSG00000124181 ENSG00000168610 ENSG00000146648 ENSG00000196396 ENSG00000160691 ENSG00000179295 PMC11798966__F1 Proposed mechanisms of NLRP3 inflammasome activation and regulation in HBV infection ENSG00000278718 ENSG00000162711 ENSG00000136869 PMC3493339__F1 ERBB Pathway ENSG00000169291 ENSG00000002330 ENSG00000110395 ENSG00000138798 ENSG00000198793 ENSG00000177606 PMC7349634__F1 Pathways of synthesis of oxylipins from Eicosapentaenoic acid (EPA) and ARA PUFAs PMC6168629__F3 Regulatory mechanisms that control the switch from PKM1 to PKM2 ENSG00000117650 ENSG00000173933 ENSG00000198793 ENSG00000136997 PMC7593653__F5 Diabetes-induced cardiac UPS dysfunction ENSG00000178573 ENSG00000285109 ENSG00000150907 ENSG00000169047 ENSG00000079999 PMC7293394__F1 Antibody-mediated complement activation in pathology and protection ENSG00000186716 ENSG00000203710 ENSG00000117335 ENSG00000166278 ENSG00000117322 ENSG00000062485 PMC4016892__F6 Schematic model illustrating the signaling pathway by which ANG suppresses the inflammatory response involving TBK1-mediated NFKB nuclear translocation in HCFs inflamed by TNFA ENSG00000150782 ENSG00000113520 PMC3246422__F10 PP-associated modulation of inflammatory chemokine production and repair-related processes in keratinocytes through EGFR system ENSG00000111537 ENSG00000163235 ENSG00000163914 ENSG00000168610 ENSG00000146648 PMC4088925__F3 Summary of expression patterns of complement components in the placenta ENSG00000113600 ENSG00000203710 ENSG00000132693 PMC7601592__F1 Most important approaches to melanoma treatment ENSG00000157404 ENSG00000157764 PMC8298002__F5 Physiological, Genomic and Transcriptomic Analyses Reveal the Adaptation Mechanisms of Acidiella bohemica to Extreme Acid Mine Drainage Environments ENSG00000167996 PMC10375050__F3 Know your neighbors: microbial recognition at the intestinal barrier and its implications for gut homeostasis and inflammatory bowel disease ENSG00000073331 ENSG00000145365 ENSG00000175104 PMC6941427__F4 Differentially expressed genes (DEGs) involved in flavonoid metabolic pathway and lignin metabolic pathway ENSG00000115263 ENSG00000145321 ENSG00000084774 PMC8400831__F4 CIDO ontology updates and secondary analysis of host responses to COVID-19 infection based on ImmPort reports and literature ENSG00000130234 ENSG00000184012 PMC6941427__F6 Differentially expressed genes (DEGs) involved in terpenoid metabolic pathway ENSG00000110921 ENSG00000197429 PMC3444914__F1 The DNA base excision repair (BER) pathway ENSG00000132646 ENSG00000177084 PMC6941427__F9 The regulatory network of key long non-coding RNAs (lncRNAs), genes, and metabolites involved in flavonoid metabolic pathway, terpenoid metabolic pathway, and jasmonic acid/methyl jasmonate (JA/MeJA) biosynthesis and signal transduction pathway ENSG00000110921 ENSG00000115263 ENSG00000084774 PMC10375050__F2 Know your neighbors: microbial recognition at the intestinal barrier and its implications for gut homeostasis and inflammatory bowel disease ENSG00000167207 ENSG00000175104 ENSG00000106100 PMC6953035__F10 Proposed model depicting the impact of PC1/3 knockdown on the activation of TLR4 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC8883233__F2 MCL1-mediated regulation of apoptosis ENSG00000171791 PMC5071578__F5 Role of TSN in carcinogenesis ENSG00000105329 ENSG00000161921 PMC5038578__F1 Molecular pathways associated with inflammatory bowel disease ENSG00000162711 ENSG00000274429 ENSG00000167207 ENSG00000187796 ENSG00000179914 ENSG00000197375 ENSG00000145777 ENSG00000237693 ENSG00000168610 ENSG00000115607 ENSG00000162594 ENSG00000118503 ENSG00000187908 ENSG00000136869 ENSG00000100219 ENSG00000113302 ENSG00000112486 PMC4278335__F4 In silico functional analyses and discovery of survival-associated microRNA signatures in pediatric osteosarcoma ENSG00000013016 ENSG00000181852 ENSG00000070831 ENSG00000136100 ENSG00000138798 ENSG00000198793 ENSG00000165527 ENSG00000131475 ENSG00000069869 ENSG00000130164 ENSG00000110395 ENSG00000078747 ENSG00000198742 ENSG00000146648 ENSG00000024422 ENSG00000178568 ENSG00000141367 PMC9494158__F4 Traditional Chinese medicine prescription Shenling BaiZhu powder to treat ulcerative colitis: Clinical evidence and potential mechanisms ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC9164031__F6 Inhibition of eNOS Partially Blunts the Beneficial Effects of Nebivolol on Angiotensin II-Induced Signaling in H9c2 Cardiomyoblasts ENSG00000198793 PMC6699409__F2 MTORC1 and MEK-ERK signaling pathways regulate eIF4F activity and assembly ENSG00000288461 PMC5513767__F1 Complementopathies ENSG00000166278 ENSG00000182326 ENSG00000236625 PMC4614807__F2 Gene Expression Profiling Identifies Interferon Signalling Molecules and IGFBP3 in Human Degenerative Annulus Fibrosus ENSG00000137273 ENSG00000185022 ENSG00000110107 ENSG00000169756 ENSG00000124766 ENSG00000125347 ENSG00000106546 ENSG00000068028 ENSG00000156802 ENSG00000125398 ENSG00000177508 ENSG00000116030 ENSG00000062485 PMC5123561__F3 Heterotrimeric G Proteins: Breaking the rules of engagement, space and time ENSG00000087245 ENSG00000171105 ENSG00000291971 ENSG00000150907 ENSG00000198793 ENSG00000136869 ENSG00000171791 ENSG00000100985 ENSG00000124181 ENSG00000168610 ENSG00000146648 PMC4614807__F8 Gene Expression Profiling Identifies Interferon Signalling Molecules and IGFBP3 in Human Degenerative Annulus Fibrosus ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000185745 ENSG00000142166 PMC6953081__F2 Regulation of eIF4F complex formation by PI3K/Akt/mTOR, MAPK/MNK, and AMPK pathways and drugs targeting these pathways PMC8014301__F1 The SphK‐S1P‐S1PRs pathway in invasion of the nervous system by SARS‐CoV‐2 infection ENSG00000148798 ENSG00000163914 ENSG00000170989 ENSG00000180739 ENSG00000213694 ENSG00000125910 ENSG00000267534 PMC8829062__F1 Deciphering the Roles of Metformin in Alzheimer’s Disease: A Snapshot ENSG00000142192 ENSG00000198793 PMC12063284__F3 SMKIs-induced cardiotoxicity ENSG00000151012 ENSG00000291971 ENSG00000162772 ENSG00000168610 ENSG00000146648 PMC8640358__F5 Network Pharmacology and Molecular Docking–Based Investigation: Prunus mume Against Colorectal Cancer via Silencing RelA Expression ENSG00000138798 ENSG00000140505 ENSG00000158517 ENSG00000171791 ENSG00000112715 ENSG00000164305 ENSG00000124762 ENSG00000183765 ENSG00000089685 ENSG00000149968 ENSG00000136997 ENSG00000166501 ENSG00000064012 ENSG00000132906 ENSG00000087245 ENSG00000104365 ENSG00000081041 ENSG00000115008 ENSG00000100906 ENSG00000065361 ENSG00000050628 ENSG00000131747 ENSG00000173039 ENSG00000140465 ENSG00000073756 ENSG00000043591 ENSG00000169245 ENSG00000134057 ENSG00000291748 ENSG00000100985 ENSG00000146648 PMC11867957__F1 Classic Wnt/Beta-catenin pathway cascade diagram ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8504100__F2 Crosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives ENSG00000178860 ENSG00000102962 ENSG00000081041 ENSG00000197635 ENSG00000163739 ENSG00000129226 ENSG00000145777 ENSG00000124875 ENSG00000049768 ENSG00000121807 ENSG00000175505 ENSG00000168610 ENSG00000121966 ENSG00000133048 ENSG00000102970 ENSG00000078098 ENSG00000204520 PMC8504100__F3 Crosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives ENSG00000108691 ENSG00000163599 ENSG00000121807 ENSG00000078098 ENSG00000168610 ENSG00000121966 PMC6497965__F6 Proposed signaling cascade for phosphorylated PCNA-promoted EMT ENSG00000149311 ENSG00000132646 PMC7749093__F1 Cardiovascular molecular imaging ENSG00000180616 ENSG00000121807 ENSG00000078098 ENSG00000121966 PMC6843074__F4 IL-22 signaling pathway for expression of acute phase response proteins ENSG00000108691 ENSG00000143546 ENSG00000149968 ENSG00000163220 ENSG00000135446 ENSG00000143556 PMC9307950__F4 Sex-biased adaptive immune regulation in cancer development and therapy ENSG00000239732 ENSG00000108786 ENSG00000129214 ENSG00000136869 PMC11866596__F1 TREM1 signaling pathway ENSG00000291603 ENSG00000187796 ENSG00000172936 ENSG00000175104 ENSG00000168610 PMC2106361__F1 Current model of the Fanconi anemia pathway ENSG00000181544 ENSG00000187790 ENSG00000115392 ENSG00000187741 ENSG00000112039 ENSG00000158169 ENSG00000131944 ENSG00000012048 ENSG00000175054 ENSG00000144554 ENSG00000132646 ENSG00000070950 ENSG00000197299 PMC6590191__F3 Interaction network formed by the encoded proteins of genes showing P values of potential relevance in our study (P < 1 × 10−4), according to the presence/absence of carotid plaques ENSG00000163637 ENSG00000073350 ENSG00000117298 ENSG00000183484 ENSG00000184381 ENSG00000111837 ENSG00000125850 ENSG00000140859 ENSG00000154928 ENSG00000128298 ENSG00000151952 ENSG00000241058 ENSG00000007866 ENSG00000153237 ENSG00000174898 ENSG00000007080 ENSG00000106100 ENSG00000291561 ENSG00000109927 ENSG00000151025 ENSG00000117245 ENSG00000035115 ENSG00000146416 ENSG00000273540 ENSG00000147724 ENSG00000276286 ENSG00000137210 ENSG00000163630 ENSG00000188517 ENSG00000152377 PMC8260388__F3 Cellular signaling cross-talk between different cardiac cell populations: an insight into the role of exosomes in the heart diseases and therapy ENSG00000130234 ENSG00000198793 PMC5339794__F3 Polymorphisms and Pharmacogenomics for the Clinical Efficacy of Methotrexate in Patients with Rheumatoid Arthritis: A Systematic Review and Meta-analysis ENSG00000228716 ENSG00000118596 ENSG00000116748 ENSG00000105329 ENSG00000136877 ENSG00000196839 ENSG00000103222 ENSG00000035928 ENSG00000137563 ENSG00000118777 ENSG00000076351 ENSG00000169245 ENSG00000179344 ENSG00000138755 ENSG00000168065 ENSG00000124275 ENSG00000136869 ENSG00000023839 PMC3837590__F3 Macrophage infiltration in adipose tissues, oxidative stress and IR ENSG00000125538 ENSG00000121807 PMC3337163__F1 Breaking up is hard to do ENSG00000017797 ENSG00000006451 ENSG00000087586 PMC2774487__F2 Pathway showing genes involved in Parkinson's disease (Courtesy: KEGG pathway) ENSG00000132906 ENSG00000115317 PMC6745219__F2 Tumor Necrosis Factor Receptor 1 (TNFR-1) Signalling Pathway ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC8003366__F1 View at a glance of the landscape of the metabolic interactions between genes and pathways discussed in the manuscript PMC7117101__F2 Mechanisms by which SND1 promotes oncogenesis ENSG00000136158 ENSG00000105656 ENSG00000123374 ENSG00000282899 PMC4096962__F6 Combinatorial cytokine regulation of iNOS expression in IMF ENSG00000111537 ENSG00000115415 ENSG00000125538 PMC3515677__F1 Summary of the mechanisms of DC-mediated HIV-1 transmission to CD4+ T cells ENSG00000121966 PMC2874080__F2 Pathway of de novo synthesis of saturated and monounsaturated fatty acids and regulation of lipogenic genes by transcription factors (LXR, SREBP-1c and ChREBP) ENSG00000170522 ENSG00000099194 ENSG00000026103 PMC9054782__F6 Hibiscus sabdariffa extract improves hepatic steatosis, partially through IRS-1/Akt and Nrf2 signaling pathways in rats fed a high fat diet ENSG00000169047 ENSG00000026103 PMC3138675__F2 Molecular mechanisms in hereditary cancer ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC5682923__F1 Complex Roles of mTOR in Adipocytes and Beyond ENSG00000177058 ENSG00000106070 ENSG00000112561 PMC5772977__F1 The transforming growth factorB1/Smad signaling pathway ENSG00000170365 ENSG00000137834 PMC9137176__F7 Granulosa cell response to luteinizing hormone is partly mediated by YAP1-dependent induction of amphiregulin ENSG00000109321 ENSG00000138039 ENSG00000145321 ENSG00000146648 PMC12072397__F3 The osteoblastogenesis signaling pathway and its lncRNA-induced regulation ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000169862 ENSG00000134982 ENSG00000168036 ENSG00000175592 ENSG00000185483 ENSG00000196470 ENSG00000253352 ENSG00000158747 ENSG00000104332 ENSG00000116161 ENSG00000095739 ENSG00000167941 ENSG00000147869 ENSG00000155011 ENSG00000113558 ENSG00000136997 ENSG00000183579 ENSG00000165879 ENSG00000108375 ENSG00000100211 ENSG00000185269 ENSG00000125968 ENSG00000087095 ENSG00000169218 ENSG00000137673 ENSG00000183691 ENSG00000067900 ENSG00000277641 ENSG00000164736 ENSG00000177606 ENSG00000076716 ENSG00000133961 ENSG00000096717 PMC4359241__F2 Androgen receptors beyond prostate cancer: an old marker as a new target ENSG00000140505 ENSG00000168610 PMC4359241__F3 Androgen receptors beyond prostate cancer: an old marker as a new target ENSG00000198793 ENSG00000164327 PMC12072397__F2 The osteoclastogenesis signaling pathway and its lncRNA-induced regulation ENSG00000170909 ENSG00000033327 ENSG00000204103 ENSG00000140968 ENSG00000007866 ENSG00000253352 ENSG00000143387 ENSG00000095585 ENSG00000110395 ENSG00000115415 ENSG00000175104 ENSG00000096717 ENSG00000131196 PMC4258442__F3 Nitrosothiol signaling and protein nitrosation in cell death ENSG00000132478 ENSG00000168040 ENSG00000026103 PMC6521150__F2 Proposed model for actinomycin D assembly (A) and 4-MHA precursor production (B) in S ENSG00000142192 ENSG00000166278 PMC8395918__F7 Physalin A, 13,14-Seco-16, 24-Cyclo-Steroid, Inhibits Stemness of Breast Cancer Cells by Regulation of Hedgehog Signaling Pathway and Yes-Associated Protein 1 (YAP1) ENSG00000128602 PMC9551033__F4 AMBRA1 and its role as a target for anticancer therapy ENSG00000110497 ENSG00000168036 ENSG00000168610 PMC7468493__F1 The signal transduction pathways associated with epithelial–mesenchymal transition (EMT) ENSG00000019991 ENSG00000168283 ENSG00000138798 ENSG00000170558 ENSG00000137449 ENSG00000153012 ENSG00000168036 ENSG00000127616 ENSG00000164916 PMC8706716__F1 Targeting AKT in ER-Positive HER2-Negative Metastatic Breast Cancer: From Molecular Promises to Real Life Pitfalls? ENSG00000002330 ENSG00000198793 PMC6387402__F1 Activation of signaling pathways in respiratory epithelial cells upon viral infection ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000164342 ENSG00000142166 PMC7217380__F2 PPI network and module analysis of HCC ENSG00000125144 ENSG00000165841 ENSG00000169715 PMC6602956__F6 Schematic diagram of NPY(1–36) expression and secretion in activated LX-2 cells and the signalling pathway involved ENSG00000163435 ENSG00000164128 ENSG00000198793 PMC1183420__F1 Simplified 13-hydroxylation pathway of GA biosynthesis in vegetative tissue of pea PMC11959038__F7 Association of LRP1B with the Hedgehog signaling pathway in CRC ENSG00000106571 ENSG00000117425 ENSG00000168702 ENSG00000134057 ENSG00000123374 ENSG00000164690 ENSG00000128602 ENSG00000183765 PMC4615219__F1 Aberrant activation of alveolar epithelial cells (AECs) in lung fibrosis ENSG00000197429 ENSG00000168036 ENSG00000164690 PMC9709420__F6 Deciphering the impact and mechanism of Trikatu, a spices-based formulation on alcoholic liver disease employing network pharmacology analysis and in vivo validation ENSG00000142192 ENSG00000111837 ENSG00000084110 ENSG00000168040 PMC4796823__F1 Identification of Potential Drug Targets in Cancer Signaling Pathways using Stochastic Logical Models ENSG00000002330 ENSG00000291971 ENSG00000198793 ENSG00000177606 ENSG00000136997 ENSG00000168610 PMC5451598__F12 Schematic pathway illustrating the inhibitory effects of BMP4 on PDGF-induced calpain-2 activation, cell proliferation, and collagen synthesis in normal and PAH PASMCs ENSG00000105329 ENSG00000171759 PMC1440308__F6 Alternative Th network ENSG00000138378 ENSG00000115415 ENSG00000107485 PMC1440308__F7 Alternative Th network ENSG00000138378 ENSG00000107485 ENSG00000113263 ENSG00000175104 PMC2965566__F2 Transcriptional control of invariant NKT cell development ENSG00000291603 ENSG00000010810 PMC8430321__F5 Network Pharmacology-Based Analysis on the Potential Biological Mechanisms of Sinisan Against Non-Alcoholic Fatty Liver Disease ENSG00000106333 PMC7460810__F1 Biogenesis pathway of YRNAs and YsRNAs ENSG00000135828 ENSG00000116747 ENSG00000132341 PMC5446478__F3 Biochemical and metabolic changes within the tumor ENSG00000131473 ENSG00000198793 ENSG00000115419 PMC7422677__F8 Index and biological spectrum of human DNase I hypersensitive sites ENSG00000138378 ENSG00000010810 ENSG00000026103 PMC5472375__F4 Based on GeneCodis3 analysis of Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, 23 significantly enriched pathways were revealed ENSG00000007908 ENSG00000091138 ENSG00000136155 ENSG00000175104 ENSG00000127191 ENSG00000146648 PMC3965409__F6 Positive Feedback Regulation of Proliferation in Vascular Smooth Muscle Cells Stimulated by Lipopolysaccharide Is Mediated through the TLR 4/Rac1/Akt Pathway ENSG00000038382 ENSG00000170458 ENSG00000172936 ENSG00000136869 PMC11638059__F3 Few molecular mechanisms by which TAM affects EC ENSG00000102962 ENSG00000143546 ENSG00000163220 ENSG00000100985 ENSG00000112715 PMC8198065__F2 PLysRS-Ap4A Pathway in Mast Cells Regulates the Switch from Host Defense to a Pathological State ENSG00000178860 ENSG00000198793 PMC4948278__F2 Cancer stem cells supporting activities of CD44v6 ENSG00000019991 ENSG00000087245 ENSG00000157227 ENSG00000026508 ENSG00000117335 ENSG00000100985 ENSG00000112186 PMC4948278__F4 CXCR4, a marker of migrating cancer stem cells ENSG00000002330 ENSG00000291971 ENSG00000026508 ENSG00000127324 ENSG00000121966 PMC7811571__F1 Graphical abstract ENSG00000162711 ENSG00000130234 ENSG00000125538 ENSG00000136869 PMC4948278__F5 EpCAM-palmitoylated claudin7 complex in pancreatic cancer stem cells ENSG00000119888 ENSG00000291971 ENSG00000026508 ENSG00000164949 PMC7811571__F2 Main TLR4 signalling pathways ENSG00000183735 ENSG00000125538 ENSG00000172005 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000175104 PMC9013884__F7 Biological Functions and Regulatory Mechanisms of Fatty Acid Binding Protein 5 in Various Diseases ENSG00000087245 ENSG00000159224 ENSG00000159128 ENSG00000117480 ENSG00000027697 ENSG00000100985 ENSG00000168610 ENSG00000146648 ENSG00000026103 PMC11596539__F3 UV damage and EGCG repair of collagen network layers in photoaged skin ENSG00000146648 PMC7538181__F1 Transcriptional regulation of memory B cell differentiation ENSG00000112576 ENSG00000140968 ENSG00000103522 ENSG00000118971 ENSG00000168610 ENSG00000081189 ENSG00000124762 ENSG00000196628 ENSG00000071564 ENSG00000186716 ENSG00000136997 ENSG00000137265 ENSG00000213999 ENSG00000283060 PMC7926484__F3 Dysregulated pathways governing liver hepcidin expression in PAH ENSG00000170365 ENSG00000010704 ENSG00000106327 ENSG00000105697 ENSG00000168610 PMC7538181__F3 Transcriptional regulation of memory B cell differentiation ENSG00000157933 ENSG00000110395 ENSG00000150907 ENSG00000186716 ENSG00000136997 ENSG00000137265 ENSG00000112182 ENSG00000124762 PMC8204445__F1 Tryptophan-kynurenine metabolism: a link between the gut and brain for depression in inflammatory bowel disease ENSG00000162882 PMC6802331__F1 Schematic diagram of the JNK signaling pathway promoting cell death in ovarian cancer ENSG00000132906 ENSG00000171791 PMC6862839__F4 Toll-like receptors (TLRs) in Lamellibrachia luymesi ENSG00000172936 ENSG00000184216 PMC4414745__F4 Regulation of rice Hd3a and RFT1 expression by photoperiod ENSG00000013016 ENSG00000163933 PMC6930256__F6 The networks of the PI3K-AKT signaling pathway related genes, representing the level of regulation of PI3K-AKT signaling pathway related genes compared with the blank control group in haemocytes, at various times when the HdAKT was inhibited by dsRNA ENSG00000104365 ENSG00000198793 ENSG00000204673 ENSG00000164327 ENSG00000108443 ENSG00000213977 ENSG00000167965 ENSG00000166971 ENSG00000188677 ENSG00000148730 ENSG00000187840 ENSG00000197702 PMC6802331__F3 JNK signaling pathway mediated drug resistance ENSG00000143799 ENSG00000077463 PMC5371185__F1 Schematic representation of the DNA damage response (DDR) pathway ENSG00000149311 ENSG00000175054 PMC7908992__F3 Main molecular mechanisms involved in the antioxidant activity and the beneficial effects of dietary polyphenols in metabolic, cardiovascular, and neurodegenerative diseases ENSG00000177169 ENSG00000112561 PMC6704558__F2 Signaling pathways for CSF-1 and FAK ENSG00000070831 ENSG00000291971 PMC8282090__F8 KEGG pathways regulated by GPA2 or ASC1 as determined by sensitivity analysis ENSG00000164338 ENSG00000177971 ENSG00000241945 ENSG00000136718 ENSG00000011260 PMC2966110__F8 Stbd1 participation in glycogen metabolism and Stbd1 structure ENSG00000291507 ENSG00000118804 ENSG00000139112 PMC7108389__F4 TNFR and TLRs induced TNF signaling pathway ENSG00000137275 ENSG00000102871 ENSG00000090686 ENSG00000172936 ENSG00000157625 ENSG00000168040 ENSG00000154124 ENSG00000175104 ENSG00000127191 PMC7108389__F2 Viral genome induced IFN production pathway via RIG-I and interacting DUBs ENSG00000135655 ENSG00000155313 ENSG00000276561 ENSG00000184979 ENSG00000183735 ENSG00000136878 ENSG00000164430 ENSG00000088888 ENSG00000140455 ENSG00000102007 ENSG00000131323 ENSG00000083799 ENSG00000143258 PMC8910759__F3 Damage-Associated Molecular Patterns (DAMPs) in Retinal Disorders ENSG00000162711 ENSG00000026508 ENSG00000175104 PMC7108389__F3 TLRs, IFNARI and IFNARII induced IFN production pathway ENSG00000184979 ENSG00000213928 ENSG00000105397 ENSG00000137275 ENSG00000115415 ENSG00000102871 ENSG00000157625 ENSG00000083799 ENSG00000168040 ENSG00000155313 ENSG00000175104 ENSG00000127191 PMC8910759__F4 Damage-Associated Molecular Patterns (DAMPs) in Retinal Disorders ENSG00000170458 ENSG00000137033 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 ENSG00000115594 PMC9301043__F1 Pathogenesis of HCC Driven by NASH and the Preventive and Therapeutic Effects of Natural Products ENSG00000042832 ENSG00000198793 PMC7382586__F1 Regulatory mechanisms of linc-ROR in breast cancer ENSG00000169554 ENSG00000165527 ENSG00000164086 PMC9187756__F1 Four ferroptosis defense pathways ENSG00000228716 ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000102967 ENSG00000254550 PMC4838319__F2 De novo synthesis of CoA is a highly conserved pathway that consists of 5 enzymatic steps: pathothenic acid phosphorylation, cysteine conjugation, decarboxylation, conjugation to an adenosyl group and phosphorylation ENSG00000138621 ENSG00000127125 PMC2790076__F5 Comparative Analysis of Gene Expression Patterns and Cell Phenotypes between Cervical and Peripheral Blood Mononuclear Cells ENSG00000174125 ENSG00000100906 ENSG00000269335 ENSG00000213341 ENSG00000150455 ENSG00000121879 ENSG00000142166 ENSG00000150782 ENSG00000169245 ENSG00000239732 ENSG00000077150 ENSG00000118785 ENSG00000170458 ENSG00000187554 ENSG00000138755 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC11593403__F10 Characterization of phenotypes in melanoma cell populations resistant to dabrafenib or AZ628 ENSG00000167601 ENSG00000157764 ENSG00000151012 ENSG00000285121 ENSG00000167468 ENSG00000167996 ENSG00000145386 PMC6365902__F1 B-cell receptor pathway, which may be dysregulated in TNBC ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000010671 PMC8029610__F1 CGAS–STING pathway as a therapeutic target in inflammatory diseases ENSG00000171855 ENSG00000183735 ENSG00000164430 PMC6365902__F2 MAPK signaling pathway, which may be dysregulated in TNBC ENSG00000104626 ENSG00000087095 ENSG00000142192 ENSG00000101474 ENSG00000170458 ENSG00000197721 ENSG00000188404 ENSG00000177606 ENSG00000130159 ENSG00000026103 PMC6105390__F4 Dietary fat and fiber interact to uniquely modify global histone post-translational epigenetic programming in a rat colon cancer progression model ENSG00000145632 ENSG00000108242 ENSG00000081181 ENSG00000103089 ENSG00000142973 ENSG00000077522 ENSG00000146477 ENSG00000182985 ENSG00000106688 ENSG00000066230 ENSG00000169032 ENSG00000118777 ENSG00000109819 ENSG00000157184 ENSG00000117054 ENSG00000144802 ENSG00000178537 ENSG00000072210 ENSG00000111863 ENSG00000117528 ENSG00000140284 ENSG00000100504 ENSG00000115594 ENSG00000103375 ENSG00000127955 ENSG00000027697 ENSG00000091138 ENSG00000099194 ENSG00000062282 ENSG00000132170 ENSG00000186204 ENSG00000169245 ENSG00000187097 ENSG00000138823 ENSG00000111684 ENSG00000115361 ENSG00000145649 ENSG00000180616 ENSG00000163959 ENSG00000168646 ENSG00000144837 ENSG00000116761 ENSG00000144959 ENSG00000134531 ENSG00000162444 PMC2898064__F3 Overlay of predicted functional interactions onto a human curated GBM pathway from the TCGA data set ENSG00000149311 ENSG00000167182 PMC6365902__F3 mTOR signaling pathway, which may be dysregulated in TNBC ENSG00000198793 ENSG00000163914 ENSG00000155792 ENSG00000176641 ENSG00000285069 PMC6956866__F3 Pue for different pathways ENSG00000177575 ENSG00000111537 ENSG00000118520 ENSG00000057663 ENSG00000121966 PMC9322024__F2 Antiaging Mechanism of Natural Compounds: Effects on Autophagy and Oxidative Stress ENSG00000175793 ENSG00000198793 ENSG00000112561 ENSG00000165280 ENSG00000096717 ENSG00000079999 PMC8029610__F2 CGAS–STING pathway as a therapeutic target in inflammatory diseases ENSG00000183735 ENSG00000164430 ENSG00000173638 ENSG00000134982 ENSG00000197594 ENSG00000154059 PMC9187756__F4 Various roles of p53 in ferroptosis ENSG00000108839 ENSG00000139514 ENSG00000161905 ENSG00000151012 ENSG00000197635 ENSG00000073756 ENSG00000124762 PMC8354203__F3 Downregulation of miR-142a Contributes to the Enhanced Anti-Apoptotic Ability of Murine Chronic Myelogenous Leukemia Cells ENSG00000005194 ENSG00000245848 ENSG00000276618 ENSG00000110330 ENSG00000147869 ENSG00000140968 ENSG00000087842 ENSG00000105810 ENSG00000078237 ENSG00000150455 ENSG00000282899 PMC7718954__F4 cGAS‐STING signaling pathway ENSG00000183735 ENSG00000164430 ENSG00000254550 PMC8441965__F7 Inhibin BA is an independent prognostic factor that promotes invasion via Hippo signaling in non-small cell lung cancer ENSG00000113645 ENSG00000139926 PMC7604619__F3 Kinase pathways deregulated in Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL) ENSG00000100385 ENSG00000122025 ENSG00000198793 ENSG00000134853 ENSG00000143322 ENSG00000171791 ENSG00000099942 ENSG00000077782 ENSG00000127948 PMC3310875__F6 Progesterone Receptor Activates Msx2 Expression by Downregulating TNAP/Akp2 and Activating the Bmp Pathway in EpH4 Mouse Mammary Epithelial Cells ENSG00000170365 ENSG00000120149 PMC8930095__F2 Talin-1 interaction network in cellular mechanotransduction (Review) ENSG00000180210 ENSG00000117525 PMC7718954__F1 Necroptosis, apoptosis, and pyroptosis signaling pathways ENSG00000278718 ENSG00000137275 ENSG00000125538 ENSG00000168404 ENSG00000285379 PMC5139081__F8 CF airway epithelium and pathogen adaptation ENSG00000172936 ENSG00000001626 PMC3499061__F2 Schematic illustrations of the two significant pathways in the genome-wide gene self-reported asbestos exposure interaction analysis ENSG00000083857 ENSG00000163131 ENSG00000127022 ENSG00000231925 ENSG00000168040 ENSG00000146648 ENSG00000084774 ENSG00000026103 PMC8184946__F8 Graph indicates the mechanisms of how TRPM2 promote pancreatic cancer proliferation and tumorigenesis ENSG00000081189 PMC8634864__F2 Evolution of memory system‐related genes ENSG00000291971 ENSG00000172005 ENSG00000074410 PMC4147963__F1 Natural killer cell cytotoxicity (NKCC) ENSG00000168040 ENSG00000084774 ENSG00000026103 PMC6530346__F5 Effect of chronic treatment with PDF and addition of AlaGln on individual pathways ENSG00000105697 ENSG00000122194 ENSG00000132693 ENSG00000106927 ENSG00000180210 ENSG00000196531 ENSG00000113905 ENSG00000186575 ENSG00000291507 ENSG00000143815 ENSG00000145192 ENSG00000163914 ENSG00000171560 ENSG00000062485 PMC6391774__F4 Levels of regulation of NKG2DL expression ENSG00000284774 ENSG00000138798 ENSG00000198793 ENSG00000185591 PMC4640466__F2 Noncanonical Wnt/calcium pathway ENSG00000087095 ENSG00000169071 ENSG00000070831 ENSG00000100592 PMC4640466__F3 Wnt inhibitors currently in clinical trials ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4640466__F1 Canonical Wnt signaling.Notes: (A) Wnt off ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC2744654__F5 ProMeTra visualization of relative metabolite pools and transcript abundances during fermentation of the l-lysine producer C ENSG00000091140 ENSG00000291368 PMC3243479__F3 Fatty acid Beta-oxidation, TG synthesis, and phospholipid biosynthesis pathways ENSG00000110514 ENSG00000133027 ENSG00000198947 PMC6029485__F1 IGF signaling pathway ENSG00000002330 ENSG00000198793 ENSG00000169047 ENSG00000140443 PMC5741523__F1 Hepatitis B Virus Persistence ENSG00000183735 ENSG00000088888 ENSG00000136869 PMC6029485__F2 IGF signaling pathway in pulmonary fibrosis ENSG00000122877 PMC6823181__F1 GPER signaling pathways in cancer cells ENSG00000163914 ENSG00000146648 PMC4857136__F1 Signaling pathways frequently deregulated in MDS ENSG00000115415 ENSG00000102871 ENSG00000056558 ENSG00000168040 ENSG00000127191 PMC2910246__F8 Induction of indoleamine 2,3-dioxygenase by interferon-gamma in human lens epithelial cells: Apoptosis through the formation of 3-hydroxykynurenine ENSG00000115415 PMC4408919__F3 Opposing effects of target overexpression reveal drug mechanisms ENSG00000228716 ENSG00000095059 ENSG00000136877 PMC7011253__F1 Schematic diagram of Chinese medicines direct and indirect regulating NFKB pathway in UC treatment ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC3818951__F1 Osteoclastogenesis ENSG00000175104 ENSG00000139687 ENSG00000143387 PMC8138161__F4 Phytochemicals as a Complement to Cancer Chemotherapy: Pharmacological Modulation of the Autophagy-Apoptosis Pathway ENSG00000118971 ENSG00000057663 PMC8872619__F3 miRNA and lncRNA Expression Networks Modulate Cell Cycle and DNA Repair Inhibition in Senescent Prostate Cells ENSG00000146648 PMC12024444__F3 The Hippo signaling pathway in osteoclasts ENSG00000129474 ENSG00000101265 ENSG00000150457 ENSG00000175104 ENSG00000131196 ENSG00000131023 PMC8138161__F5 Phytochemicals as a Complement to Cancer Chemotherapy: Pharmacological Modulation of the Autophagy-Apoptosis Pathway ENSG00000198793 ENSG00000171791 ENSG00000057663 PMC8872619__F4 miRNA and lncRNA Expression Networks Modulate Cell Cycle and DNA Repair Inhibition in Senescent Prostate Cells ENSG00000149311 ENSG00000175054 ENSG00000064393 PMC8138161__F2 Phytochemicals as a Complement to Cancer Chemotherapy: Pharmacological Modulation of the Autophagy-Apoptosis Pathway ENSG00000168040 ENSG00000084774 ENSG00000026103 PMC10311114__F2 Adiponectin and metabolic cardiovascular diseases: Therapeutic opportunities and challenges ENSG00000159346 ENSG00000285070 PMC12024444__F1 Hippo signaling pathway regulates cell homeostasis under many factors ENSG00000149269 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC8872619__F2 miRNA and lncRNA Expression Networks Modulate Cell Cycle and DNA Repair Inhibition in Senescent Prostate Cells ENSG00000134057 ENSG00000145386 ENSG00000146648 ENSG00000080839 ENSG00000282899 PMC8138161__F3 Phytochemicals as a Complement to Cancer Chemotherapy: Pharmacological Modulation of the Autophagy-Apoptosis Pathway ENSG00000180210 ENSG00000177169 ENSG00000083290 ENSG00000198793 ENSG00000168040 ENSG00000026103 PMC12024444__F2 YAP/TAZ have different regulatory effects on different stages of osteogenic and chondrogenic differentiation ENSG00000178860 ENSG00000000419 ENSG00000125398 ENSG00000157601 ENSG00000206538 ENSG00000168036 ENSG00000108821 ENSG00000131196 PMC7366109__F5 KEGG signaling pathway enrichment network of Pre-No ENSG00000171105 ENSG00000081041 ENSG00000002330 ENSG00000138798 ENSG00000198793 ENSG00000141639 ENSG00000173039 ENSG00000137193 ENSG00000112715 ENSG00000132170 ENSG00000108691 ENSG00000102245 ENSG00000128052 ENSG00000177606 ENSG00000136997 ENSG00000113520 ENSG00000139687 PMC8138161__F1 Phytochemicals as a Complement to Cancer Chemotherapy: Pharmacological Modulation of the Autophagy-Apoptosis Pathway ENSG00000177169 ENSG00000110497 ENSG00000198382 ENSG00000083290 ENSG00000198793 ENSG00000144848 ENSG00000005893 ENSG00000145782 ENSG00000057663 PMC3445776__F1 The Hedgehog signaling pathway ENSG00000128602 PMC8872619__F5 miRNA and lncRNA Expression Networks Modulate Cell Cycle and DNA Repair Inhibition in Senescent Prostate Cells ENSG00000157554 ENSG00000002330 ENSG00000123374 ENSG00000171791 ENSG00000167034 ENSG00000104368 PMC8535862__F2 Phosphatidylinositol 3-Kinase Catalytic Subunit Type 3 in the Pathogenesis of Human Cancer ENSG00000177169 ENSG00000110497 ENSG00000198382 ENSG00000126775 ENSG00000162595 ENSG00000291971 ENSG00000148572 ENSG00000116030 ENSG00000171791 ENSG00000168610 ENSG00000155090 PMC11036658__F9 Targeted inhibition of the PI3K/AKT/mTOR pathway by (+)-anthrabenzoxocinone induces cell cycle arrest, apoptosis, and autophagy in non-small cell lung cancer ENSG00000198793 PMC4335789__F1 Mechanisms that promote resistance to PI3K pathway inhibition ENSG00000198793 PMC8138161__F6 Phytochemicals as a Complement to Cancer Chemotherapy: Pharmacological Modulation of the Autophagy-Apoptosis Pathway ENSG00000198793 ENSG00000136869 ENSG00000074410 PMC4905241__F1 Cell cycle-dependent regulation of E2F1 ENSG00000145604 ENSG00000149311 ENSG00000039537 ENSG00000136997 ENSG00000126457 PMC4905241__F2 DNA damage-dependent regulation of E2F1 ENSG00000149311 ENSG00000175054 ENSG00000126457 ENSG00000285246 ENSG00000120868 ENSG00000171791 ENSG00000145391 PMC11395567__F2 Simplified illustration of the signalling pathway depicting priming and activation of the NLRP3 inflammasome ENSG00000278718 ENSG00000162711 ENSG00000185515 ENSG00000102871 ENSG00000172936 ENSG00000168040 ENSG00000184216 PMC11279438__F1 Vitamin D’s role in skeletal muscle ENSG00000105516 ENSG00000107611 PMC11279438__F2 Relationship between oxidative stress and weakness of muscle ENSG00000096717 PMC8328045__F5 Non-Transferrin-Bound Iron in the Spotlight: Novel Mechanistic Insights into the Vasculotoxic and Atherosclerotic Effect of Iron ENSG00000125538 ENSG00000136869 ENSG00000160179 ENSG00000174059 ENSG00000123268 PMC4905454__F3 Cancer stem cells and signaling pathways in radioresistance ENSG00000148400 ENSG00000163235 ENSG00000198793 ENSG00000026508 ENSG00000168036 PMC7721054__F2 Anatomy of an mRNA ENSG00000163435 PMC8328045__F3 Non-Transferrin-Bound Iron in the Spotlight: Novel Mechanistic Insights into the Vasculotoxic and Atherosclerotic Effect of Iron ENSG00000162711 ENSG00000172936 ENSG00000136869 ENSG00000162692 PMC11279438__F3 Antioxidative role of vitamin D in muscle dysfunction ENSG00000116688 ENSG00000096717 ENSG00000171109 ENSG00000079999 PMC7985100__F3 Signaling pathways and gene regulation on NLRP3 inflammasome ENSG00000162711 ENSG00000137275 ENSG00000100697 ENSG00000168036 ENSG00000265972 ENSG00000168404 ENSG00000285379 PMC8440972__F3 Houttuynia cordata Thunb: An Ethnopharmacological Review ENSG00000079999 PMC4584313__F2 Hedgehog Signaling in Malignant Pleural Mesothelioma ENSG00000106571 ENSG00000128602 PMC11566155__F10 Novel function for Alpha-synuclein as a regulator of NCK2 in olfactory bulb: implications for its role in olfaction ENSG00000116106 ENSG00000163914 ENSG00000071051 PMC4905454__F1 Cancer stem cells and signaling pathways in radioresistance ENSG00000002330 ENSG00000163235 ENSG00000198793 ENSG00000123374 ENSG00000087842 ENSG00000139618 PMC4849016__F2 Regulation of RNase 7 induction ENSG00000168610 ENSG00000146648 PMC10394732__F2 Mechanisms involved in mutant p53 exerting GOF effects ENSG00000066117 ENSG00000136997 ENSG00000104432 PMC3245324__F2 Ischemic preconditioning (IPC): signaling pathways and targets ENSG00000291971 ENSG00000198793 PMC5541046__F7 Working model of the EphA4–ephexin1 signaling pathway and BDNF-TrkB signaling pathway in the model of depression ENSG00000116106 ENSG00000010810 PMC8699295__F3 TRPM7 Ion Channel: Oncogenic Roles and Therapeutic Potential in Breast Cancer ENSG00000092439 ENSG00000176692 ENSG00000138798 ENSG00000124766 ENSG00000146648 PMC11720051__F2 Diagram of Hippo Signaling Pathway “on” & “off” states ENSG00000188786 ENSG00000186575 ENSG00000150457 ENSG00000131023 ENSG00000291442 PMC7579731__F1 Contemporary treatment approaches for metastatic colorectal cancer driven by BRAF V600 mutations ENSG00000157764 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC3602516__F1 Identification of Small Molecule Activators of BMP Signaling ENSG00000170365 ENSG00000137834 ENSG00000125968 PMC11173247__F8 Wound-induced genes involved in plant–insect interactions in arabidopsis WT and lox2 mutants ENSG00000205517 ENSG00000136997 ENSG00000105227 PMC5214941__F2 Proinflammatory role of extracellular interleukin (IL)-1A ENSG00000115590 ENSG00000115594 PMC4050127__F1 Targeting LIM kinase in cancer and neurofibromatosis ENSG00000196712 ENSG00000182541 PMC7655196__F1 Summary scheme of MerTK-mediated macrophage HSC crosstalk pathway in fibrotic NASH ENSG00000153208 ENSG00000105329 PMC7326904__F1 Evaluation of Silencing Effect of miR-133a-5p Mimic on TIM-3 Expression in AML (HL-60) Cell Line ENSG00000087095 ENSG00000102871 ENSG00000177606 ENSG00000130159 ENSG00000127191 ENSG00000026103 PMC4045235__F3 CUL7-OBSL1-CCDC8 pathway and its predicted role in cell growth ENSG00000044090 ENSG00000171105 ENSG00000169047 PMC10925900__F7 Amyloid-Beta-Induced Dendritic Spine Elimination Requires Ca2+-Permeable AMPA Receptors, AKAP-Calcineurin-NFAT Signaling, and the NFAT Target Gene Mdm2 ENSG00000285485 PMC8526962__F4 Everything Old Is New Again: Drug Repurposing Approach for Non-Small Cell Lung Cancer Targeting MAPK Signaling Pathway ENSG00000132906 ENSG00000002330 ENSG00000146648 ENSG00000122008 PMC8526962__F5 Everything Old Is New Again: Drug Repurposing Approach for Non-Small Cell Lung Cancer Targeting MAPK Signaling Pathway ENSG00000163235 ENSG00000138798 PMC6540369__F1 a Biosynthetic pathway of glycyrrhetinic acid constructed in S ENSG00000197429 PMC6703648__F7 Proposed model for the role of the Rb/E2F pathway in the coordination of proliferation and differentiation during neurogenesis ENSG00000165891 PMC4917665__F2 Metabolic pathway of aerobic glycolysis, FAS and FAO ENSG00000157184 ENSG00000131473 ENSG00000065833 ENSG00000169710 ENSG00000159399 PMC9290266__F8 RA signaling pathway combined with Wnt signaling pathway regulates human-induced pluripotent stem cells (hiPSCs) differentiation to sinus node-like cells ENSG00000112837 ENSG00000138622 ENSG00000006283 ENSG00000135111 ENSG00000164093 ENSG00000168779 ENSG00000089225 PMC8670263__F1 CGAS–STING pathway: more than fighting against viruses and cancer ENSG00000183735 ENSG00000164430 PMC8253380__F1 Mechanistic Overview of Taste Bud Maintenance and Impairment in Cancer Therapies ENSG00000164690 ENSG00000114315 ENSG00000139352 PMC8253380__F2 Mechanistic Overview of Taste Bud Maintenance and Impairment in Cancer Therapies ENSG00000281324 ENSG00000162337 ENSG00000102312 ENSG00000168036 ENSG00000128602 PMC5144577__F1 Canonical Notch signaling and Notch conservation between human and Monosiga brevicollis ENSG00000138798 ENSG00000133961 ENSG00000184916 PMC5874734__F1 Induction of necrosis by L ENSG00000154059 ENSG00000168404 ENSG00000285379 PMC6678606__F1 Stearoyl-CoA desaturase 1 (SCD1) as a molecular target for anticancer therapy ENSG00000138798 ENSG00000168036 ENSG00000146648 PMC6514153__F3 Reelin signaling pathway in Golgi Dynamics and morphology ENSG00000106683 ENSG00000163539 ENSG00000070831 ENSG00000291971 ENSG00000173406 PMC11087106__F7 High-dose Vitamin C injection ameliorates against sepsis-induced myocardial injury by anti-apoptosis, anti-inflammatory and pro-autophagy through regulating MAPK, NFKB and PI3K/AKT/mTOR signaling pathways in rats ENSG00000198793 PMC5474195__F2 Novel therapeutic approaches for disease-modification of epileptogenesis for curing epilepsy ENSG00000168036 PMC5797575__F8 Proposed scheme of the possible mechanisms associated with the effects of asiaticoside (AS) on attenuation of cell growth inhibition and apoptosis induced by AB1-42 in human brain microvascular endothelial cells (hBMECs) ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC4490961__F2 Interaction of the TFF2-CXCR4 axis with the active RAS-RAF-MEK-ERK pathway in the serrated pathway of colorectal cancer ENSG00000138798 ENSG00000160181 ENSG00000146648 ENSG00000121966 PMC7281527__F1 Canonical microRNA (miRNA) biogenesis pathway ENSG00000128191 ENSG00000113360 PMC4308035__F1 Proposed pathways by which prostate cancer cells activate AR signaling, including variants (AR-Vs), and thus acquire resistance to AR-directed therapy PMC4199664__F1 Cell cycle regulatory pathways ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000078237 ENSG00000284194 ENSG00000146648 ENSG00000196712 PMC7565308__F5 Systems biology analysis ENSG00000160789 ENSG00000119888 ENSG00000134308 ENSG00000072274 ENSG00000100345 ENSG00000169710 ENSG00000164305 ENSG00000007171 ENSG00000160752 ENSG00000125691 ENSG00000076554 ENSG00000080371 ENSG00000106070 ENSG00000138119 ENSG00000132341 ENSG00000122678 PMC8406742__F2 Neutrophil Extracellular Traps in Cancer ENSG00000125538 ENSG00000189403 ENSG00000005381 ENSG00000146648 PMC7411791__F1 Toll-like receptor (TLR) signaling in response to viral infection ENSG00000183735 ENSG00000137275 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC8748997__F8 The proposed model ENSG00000105397 ENSG00000198793 ENSG00000118520 ENSG00000142166 PMC3845556__F1 Targeting the PI3K-AKT-mTOR signaling network in cancer ENSG00000198793 PMC7565308__F6 Global subnetwork analyses ENSG00000105369 ENSG00000100906 ENSG00000198793 ENSG00000171791 ENSG00000168040 ENSG00000010671 ENSG00000185104 ENSG00000118503 ENSG00000089685 ENSG00000136997 ENSG00000166501 ENSG00000197943 ENSG00000131323 ENSG00000175104 ENSG00000064012 ENSG00000198286 PMC7859290__F1 Biosynthesis of the molybdenum cofactor (Moco) and metabolic pathway of sulfur amino acids and purine degradation ENSG00000124217 ENSG00000164172 ENSG00000171723 PMC4033628__F2 Synthesis of representative structures along the Golgi-centric core M1 and M2 glycan synthesis pathways ENSG00000144647 ENSG00000009830 ENSG00000130714 ENSG00000109956 PMC7897327__F2 m6A RNA modification regulates hematopoietic system development ENSG00000088888 ENSG00000144895 ENSG00000198492 ENSG00000171791 ENSG00000168646 ENSG00000165819 PMC4033628__F3 Representative core M3 structures that are dependent on multiple initial activities based in the ER ENSG00000144647 ENSG00000185900 ENSG00000009830 ENSG00000130714 ENSG00000165905 ENSG00000282880 PMC7349681__F2 Types of extrusion ENSG00000163914 ENSG00000267534 PMC12254754__F2 Schematic illustrates that inhibition of GLUT1 results in an increase in the tumor OXPHOS pathway, leading to excessive production of ROS, which subsequently promotes TNFAlpha-mediated cell death ENSG00000169245 ENSG00000186810 ENSG00000138755 PMC6933354__F6 Schematic model indicating that SPRY4‐IT1 competitively binds to miR‐217 and TCF7L2, consequently regulating the Wnt/B‐catenin signalling pathway to promote stemness of breast cancer cells ENSG00000134982 ENSG00000168036 PMC9542654__F4 Exploration of hub genes involved in PCOS using biological informatics methods ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000169047 ENSG00000136997 ENSG00000104894 PMC8383754__F3 Identification of HIF-1A/VEGFA signaling pathway and transcription factors in Kashin-Beck disease by integrated bioinformatics analysis ENSG00000132906 ENSG00000087245 ENSG00000142192 ENSG00000111537 ENSG00000118785 ENSG00000125538 ENSG00000198793 ENSG00000177606 ENSG00000026508 ENSG00000100985 ENSG00000164305 ENSG00000007171 PMC9608206__F2 Clinical implications of the interaction between PD-1/PD-L1 and PI3K/AKT/mTOR pathway in progression and treatment of non-small cell lung cancer ENSG00000136997 ENSG00000168036 ENSG00000168610 PMC11002130__F4 tsRNAs as inhibitors of MAPK pathway activation via targeting MAPK-related proteins ENSG00000070831 ENSG00000163914 PMC8383754__F5 Identification of HIF-1A/VEGFA signaling pathway and transcription factors in Kashin-Beck disease by integrated bioinformatics analysis ENSG00000116044 ENSG00000130522 ENSG00000105516 ENSG00000198793 ENSG00000173039 ENSG00000182759 ENSG00000171791 ENSG00000112715 ENSG00000007171 ENSG00000197063 ENSG00000111537 ENSG00000177606 ENSG00000198517 ENSG00000166501 PMC2659375__F2 MET as a target for treatment of chest tumours ENSG00000070831 ENSG00000291971 ENSG00000163914 ENSG00000089159 PMC8317503__F1 Knockout Gene-Based Evidence for PIWI-Interacting RNA Pathway in Mammals ENSG00000142182 ENSG00000095627 ENSG00000152670 ENSG00000180113 ENSG00000134668 ENSG00000173809 ENSG00000133863 PMC7393201__F7 Astaxanthin attenuates hepatic damage and mitochondrial dysfunction in non‐alcoholic fatty liver disease by up‐regulating the FGF21/PGC‐1A pathway ENSG00000105550 ENSG00000125538 ENSG00000077782 PMC4307801__F1 HER2-Positive Breast Cancer: Current Management of Early, Advanced, and Recurrent Disease ENSG00000002330 ENSG00000291971 ENSG00000198793 PMC5486146__F1 Thyroid cancer hystotypes and their causative genetic events ENSG00000157764 ENSG00000168036 PMC4270129__F1 This figure shows the VEGF pathway for angiogenesis ENSG00000163739 ENSG00000169429 ENSG00000120868 PMC4829549__F2 MET signaling pathway ENSG00000019991 ENSG00000002330 ENSG00000291971 ENSG00000198793 ENSG00000168610 PMC8728240__F2 Priority index: database of genetic targets in immune-mediated disease ENSG00000136997 ENSG00000127191 ENSG00000140464 PMC3526895__F9 Schematic model of the signaling pathway activated by redox/metabolic imbalance and its possible positive impact on human lifespan ENSG00000109819 ENSG00000116044 PMC9312948__F2 Mitochondrial HSP90 Paralog TRAP1: Structural Dynamics, Interactome, Role in Metabolic Regulation, and Inhibitors ENSG00000291971 ENSG00000136997 ENSG00000142082 PMC9228579__F3 Immunobiology of Nipah Virus ENSG00000213928 ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000168610 PMC8074097__F6 Adenosine A1 Receptor Agonist (R-PIA) before Pilocarpine Modulates Pro- and Anti-Apoptotic Factors in an Animal Model of Epilepsy ENSG00000002330 ENSG00000153574 PMC4690264__F1 Type I IFN signaling pathway and transcriptional changes of selected ISGs in the spinal cord of TMEV- compared to mock-infected SJL/J mice ENSG00000187608 ENSG00000183486 ENSG00000157601 PMC6747431__F5 The different expression of HH (hedgehog) signaling ENSG00000107338 ENSG00000128602 ENSG00000139832 ENSG00000122194 PMC3464048__F1 Large granular lymphocyte leukemia: from dysregulated pathways to therapeutic targets ENSG00000198793 ENSG00000168040 ENSG00000168610 ENSG00000026103 PMC3464048__F2 Large granular lymphocyte leukemia: from dysregulated pathways to therapeutic targets ENSG00000291971 ENSG00000136997 ENSG00000168610 PMC1849962__F5 Regulatory networks model of GSL biosynthetic pathway in Arabidopsis accession Columbia ENSG00000180210 ENSG00000110395 ENSG00000088926 PMC12242330__F1 Phenylpropanoids metabolism: recent insight into stress tolerance and plant development cues ENSG00000105227 ENSG00000084774 PMC12093320__F1 Genes encoding downstream NFLs evolve at a slower and more consistent rate comopared to genes encoding upstream NFLs ENSG00000112343 ENSG00000164161 ENSG00000050165 ENSG00000168036 ENSG00000185187 ENSG00000150457 ENSG00000114315 ENSG00000168646 ENSG00000131023 PMC6044425__F2 The N-linked protein glycosylation pathway ENSG00000101901 ENSG00000000419 ENSG00000198380 ENSG00000139133 ENSG00000033011 ENSG00000172269 ENSG00000088035 ENSG00000120697 ENSG00000214160 ENSG00000136908 PMC8470960__F2 Effects of Intermittent Fasting on Brain and Cognitive Function ENSG00000198793 PMC2756474__F7 CREB Mediates Prostaglandin F2Alpha-Induced MUC5AC Overexpression ENSG00000291363 ENSG00000125538 ENSG00000115594 PMC4110182__F1 SMN control of RNP assembly: from post-transcriptional gene regulation to motor neuron disease ENSG00000236826 ENSG00000142252 ENSG00000152147 ENSG00000046647 ENSG00000170860 ENSG00000092208 ENSG00000130332 ENSG00000130520 ENSG00000164167 PMC6469489__F1 Multiple pathway stimulation of ADAM activity, leading to sAPPA proliferation and notch stimulation ENSG00000142192 ENSG00000138798 ENSG00000146648 PMC11604893__F1 Tumor energy metabolism: implications for therapeutic targets ENSG00000198793 PMC9072795__F1 Molecular signaling in temporomandibular joint osteoarthritis ENSG00000154736 ENSG00000106571 ENSG00000069482 ENSG00000184634 ENSG00000168036 ENSG00000128602 ENSG00000077782 ENSG00000137845 ENSG00000163501 ENSG00000158859 PMC4440618__F5 Chlamydia pneumoniae Inclusion Membrane Protein Cpn1027 Interacts with Host Cell Wnt Signaling Pathway Regulator Cytoplasmic Activation/Proliferation-Associated Protein 2 (Caprin2) ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000110888 PMC11604893__F3 SWI/SNF complex regulating tumor metabolismThe purple gene and arrow represent glucose metabolism ENSG00000131473 ENSG00000067057 ENSG00000161533 ENSG00000169710 ENSG00000099194 ENSG00000127616 ENSG00000132170 PMC6225799__F6 Activation of the interferon-ɣ/STAT1 pathway ENSG00000004455 PMC5817726__F2 Role of Bruton’s tyrosine kinase downstream of the B cell receptor ENSG00000177455 ENSG00000124102 ENSG00000186716 ENSG00000136997 ENSG00000197943 ENSG00000010671 ENSG00000198286 PMC10855951__F5 Transcriptomic Analysis Provides Insights into Candidate Genes and Molecular Pathways Involved in Growth of Mytilus coruscus Larvae ENSG00000106571 ENSG00000166813 ENSG00000205250 ENSG00000128602 PMC6224961__F2 Regulation of priming and fusion of insulin granules by glucose and the incretin GLP-1 ENSG00000001626 ENSG00000132639 PMC7259377__F6 GLS1-mediated reduction of oxidative stress is associated with increased phospholipid synthesis and the activation of folate and methionine cycles ENSG00000151224 ENSG00000042832 ENSG00000185813 ENSG00000174915 ENSG00000136371 ENSG00000116761 ENSG00000156471 ENSG00000241878 ENSG00000133027 PMC7246647__F2 Oncogenic FGFR signaling in gastrointestinal stromal tumors (GISTs) ENSG00000102974 PMC6206165__F9 Model showing possible mechanism for regulation of ovarian development by four key miRNA/gene pairs ENSG00000134982 ENSG00000198742 ENSG00000174804 ENSG00000168036 ENSG00000106483 PMC7246647__F1 Fibroblast Growth Factor Receptor (FGFR) structure, ligand binding and signaling ENSG00000167900 PMC4221550__F3 smicroRNA-340 as a modulator of RAS-RAF-MAPK signaling in melanoma ENSG00000172680 ENSG00000157764 ENSG00000138798 ENSG00000136997 ENSG00000146648 PMC8131586__F6 Illustration of the positive feedback loop between tamoxifen-resistant ER-positive breast cancer cells and M2-like TAMs ENSG00000138798 ENSG00000118520 ENSG00000168610 ENSG00000146648 PMC10244098__F2 N7-methylguanosine modification: from regulatory roles to therapeutic implications in cancer ENSG00000160193 ENSG00000101654 ENSG00000137574 PMC7072743__F2 Activation of the mechanistic target of rapamycin (mTOR) ENSG00000169047 ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC2857869__F4A Metabolic Engineering for Production of Biorenewable Fuels and Chemicals: Contributions of Synthetic Biology ENSG00000261701 ENSG00000008130 PMC3049838__F3 Wnt signaling pathway activation in R1A deficient tumor cells ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3800433__F1 The central role of group 2 innate lymphoid cells (ILC2s) in type 2 immunity ENSG00000137033 ENSG00000145777 ENSG00000166090 ENSG00000146648 ENSG00000106546 PMC2742089__F3 A biochemical pathway of secreted proteins that regulate D-V patterning in Xenopus ENSG00000168487 PMC5607250__F9 Predicted regulation relationships between differentially expressed miRNAs and target genes based on KEGG pathway ENSG00000113494 ENSG00000158125 PMC8127529__F2 Azithromycin: Immunomodulatory and antiviral properties for SARS-CoV-2 infection ENSG00000130234 ENSG00000184012 PMC4632976__F1 The intracellular parasite Toxoplasma gondii depends on the synthesis of long chain and very long-chain unsaturated fatty acids not supplied by the host cell ENSG00000011007 ENSG00000154582 PMC6690620__F1 Biochemical pathway of the creation of homocysteine and specific enzymes/vitamins necessary for conversion to methionine vs PMC8642426__F2 Pharmacological insights into autophagy modulation in autoimmune diseases ENSG00000177169 ENSG00000164430 ENSG00000167207 ENSG00000144848 ENSG00000237693 ENSG00000145782 ENSG00000057663 ENSG00000164342 PMC2785619__F2 Up-regulation of TGFB signaling in Timp3−/−-AB hearts ENSG00000136603 ENSG00000170365 ENSG00000157933 ENSG00000111537 ENSG00000005339 ENSG00000095739 ENSG00000118785 ENSG00000183691 ENSG00000177606 ENSG00000134363 ENSG00000020633 ENSG00000128342 PMC4249087__F8 The UPR-induced HAdV infection boost by GCA ENSG00000115271 ENSG00000166278 PMC3520888__F1 Escorting Ras ENSG00000176108 ENSG00000132612 ENSG00000146648 PMC3192435__F2 Targeting the PI3K/Akt/mTOR pathway to treat lymphoma PMC6788945__F3 Sex-differential regulatory network ENSG00000163131 ENSG00000136155 ENSG00000100445 ENSG00000184481 ENSG00000139899 ENSG00000088970 PMC3535856__F6 Proposed mechanism for MCME-mediated inhibition against migration of CL1 cells ENSG00000291971 ENSG00000168036 PMC6962451__F5 The proteome landscape generated by the direct comparison between cells differentiating in alginate capsules and Matrigel differentiated-cells ENSG00000149311 ENSG00000012048 ENSG00000198793 ENSG00000163914 PMC5682960__F7 Working model of the action of PEDF + DHA in enhancing corneal nerve regeneration ENSG00000146469 ENSG00000169474 ENSG00000122194 ENSG00000288455 PMC2575530__F2 Insulin-like growth factor-I signaling pathway involved in breast cancer ENSG00000002330 ENSG00000169047 ENSG00000198793 ENSG00000115904 PMC9113874__F7 Transactivation at C-TAD Domain of HIF-1A by Factor-Inhibiting HIF-1A (FIH-1): A Potential Target for Therapeutic Intervention in Cancer ENSG00000132478 PMC7037626__F1 Protein interaction network of MMPs, collagen II and aggrecan ENSG00000087245 ENSG00000107562 ENSG00000106333 ENSG00000169344 ENSG00000145681 ENSG00000005961 ENSG00000113070 ENSG00000113140 ENSG00000198598 ENSG00000167346 ENSG00000132693 ENSG00000136457 ENSG00000011422 ENSG00000149968 ENSG00000197971 ENSG00000137674 ENSG00000157766 ENSG00000132692 ENSG00000123342 ENSG00000198670 ENSG00000126838 ENSG00000158859 ENSG00000188783 PMC3055988__F2 Further implications of G-/GM-CSF-induced JAK-STAT signaling in peripheral sensory neurons ENSG00000168610 ENSG00000196689 ENSG00000185313 PMC10304636__F4 Schematic diagram representing cardioprotective molecular mechanisms of GLP-1 analogs in cardiomyocytes ENSG00000102385 ENSG00000002330 ENSG00000116688 ENSG00000198793 ENSG00000171109 PMC9258689__F5 Interaction mechanism of nickel ions with L929 cells based on integrative analysis of proteomics and metabolomics data ENSG00000059573 ENSG00000116649 PMC8330049__F1 Molecules linked to Ras signaling as therapeutic targets in cardiac pathologies ENSG00000291971 ENSG00000196712 PMC9258689__F4 Interaction mechanism of nickel ions with L929 cells based on integrative analysis of proteomics and metabolomics data ENSG00000102145 ENSG00000167468 ENSG00000002549 ENSG00000116649 PMC8180257__F7 MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus ENSG00000169071 ENSG00000129654 ENSG00000185483 ENSG00000143995 PMC4949768__F1 Central carbon metabolism model for M ENSG00000261701 ENSG00000122966 ENSG00000172005 PMC5849286__F1 Sphingolipids and Redox Signaling in Renal Regulation and Chronic Kidney Diseases ENSG00000173599 ENSG00000102172 PMC4947675__F1 Non-canonical autophagy in the clearance of dead cells ENSG00000177169 ENSG00000198382 ENSG00000057663 PMC5899024__F6 For Therapeutic Targeting of AKAP Signaling Complexes in Nervous System Disorders ENSG00000242689 PMC8412110__F5 Cdc42 signalling in cell migration ENSG00000070831 ENSG00000168610 ENSG00000135905 PMC3690396__F7 Regulation of the Hippo pathway by cAMP-PKA signaling ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC8038986__F1 Contribution of cell death signaling to blood vessel formation ENSG00000171791 ENSG00000168404 ENSG00000285379 PMC8990811__F1 Impacts of the STING‐IFNAR1‐STAT1‐IRF1 pathway on the cellular immune reaction induced by fractionated irradiation ENSG00000116815 ENSG00000081237 ENSG00000181847 ENSG00000134982 ENSG00000197471 ENSG00000163599 ENSG00000160223 ENSG00000150637 ENSG00000188389 PMC6917045__F2 Interplay between the UFM1 pathway, ER stress and cell fate ENSG00000128272 ENSG00000143222 ENSG00000291971 ENSG00000120686 ENSG00000081307 PMC6917045__F3 Control of proteostasis by the ufmylation pathway ENSG00000014123 ENSG00000143222 ENSG00000120686 ENSG00000161970 PMC12185702__F6 MAPK/OIS/SASP axis in pLGG cells ENSG00000149311 ENSG00000175054 ENSG00000198380 ENSG00000178999 ENSG00000135446 ENSG00000125538 ENSG00000169047 ENSG00000204531 ENSG00000123374 ENSG00000105810 ENSG00000166851 PMC3335094__F3 Mechanical Strain Regulates Osteoblast Proliferation through Integrin-Mediated ERK Activation ENSG00000087095 ENSG00000172680 ENSG00000170458 ENSG00000130159 ENSG00000081189 ENSG00000196712 ENSG00000026103 PMC11648424__F2 Compound target–protein–protein interaction functional enrichment network of A ENSG00000143799 ENSG00000167601 ENSG00000094631 ENSG00000163464 ENSG00000169925 ENSG00000228716 ENSG00000157404 ENSG00000137601 ENSG00000178999 ENSG00000143839 ENSG00000108443 ENSG00000157184 ENSG00000141867 ENSG00000183735 ENSG00000171720 ENSG00000213658 ENSG00000064989 ENSG00000095303 ENSG00000077782 ENSG00000276996 ENSG00000120915 ENSG00000101224 ENSG00000099194 ENSG00000164120 ENSG00000127334 ENSG00000132170 ENSG00000148680 ENSG00000067955 ENSG00000096717 ENSG00000002330 ENSG00000070831 ENSG00000291971 ENSG00000050748 ENSG00000198793 ENSG00000291803 ENSG00000087085 ENSG00000196591 ENSG00000113161 ENSG00000169032 ENSG00000196396 ENSG00000144476 ENSG00000010671 ENSG00000180210 ENSG00000115828 ENSG00000184845 ENSG00000138744 ENSG00000196549 ENSG00000113263 ENSG00000125255 ENSG00000112742 ENSG00000114999 ENSG00000168748 ENSG00000109991 ENSG00000005339 ENSG00000157764 ENSG00000108861 ENSG00000174417 ENSG00000145391 ENSG00000117020 ENSG00000185386 ENSG00000135446 ENSG00000164362 ENSG00000171608 ENSG00000196689 ENSG00000163517 ENSG00000105723 ENSG00000137055 PMC5688007__F2 Mitochondrion: a central architect of copper homeostasis ENSG00000240230 ENSG00000133028 ENSG00000142082 PMC4603304__F5 Signaling pathway analysis of the potential mature EBOV miRNA target genes ENSG00000137275 ENSG00000110876 ENSG00000160202 PMC6349928__F1 Non-coding RNAs as integrators of the effects of age, genes, and environment on ovarian aging ENSG00000104899 PMC2899674__F1 Molecular pathway for arterial, venous and lymphatic cell fate determination in vertebrate embryo ENSG00000196411 ENSG00000117707 ENSG00000285438 ENSG00000203883 PMC4367606__F2 Tumor cell ligands recognized by human GD T cells ENSG00000131019 ENSG00000130202 ENSG00000111981 ENSG00000134982 ENSG00000197971 ENSG00000197429 ENSG00000198125 ENSG00000231179 ENSG00000204520 PMC9170129__F10 Evidence for Neuropeptide W Acting as a Physiological Corticotropin-releasing Inhibitory Factor in Male Chickens ENSG00000277339 ENSG00000185231 ENSG00000177606 ENSG00000115138 ENSG00000291946 PMC6487485__F1 Altered Bile Acid Profile Associates with Cognitive Impairment in Alzheimer’s Disease – An Emerging Role for Gut Microbiome ENSG00000180432 ENSG00000099377 ENSG00000115271 ENSG00000135929 PMC11849638__F9 Schematic depiction of the PKA/SHP2/STAT1 pathway ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000113448 ENSG00000142166 PMC5055439__F1 Stem cell metabolism ENSG00000198793 ENSG00000140464 PMC4404318__F1 Toll-Like Receptor Signaling in Vertebrates: Testing the Integration of Protein, Complex, and Pathway Data in the Protein Ontology Framework ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000010671 ENSG00000164342 PMC8183764__F1 Fructose and metabolic diseases: too much to be good ENSG00000262785 ENSG00000138030 ENSG00000169710 ENSG00000136872 PMC6388657__F6 IPA to identify the signaling pathway associated with the differentially expressed proteins across all the conditions studied ENSG00000145192 ENSG00000167074 ENSG00000000971 ENSG00000276838 PMC3877388__F6 Syndecan-1 (CD138) Modulates Triple-Negative Breast Cancer Stem Cell Properties via Regulation of LRP-6 and IL-6-Mediated STAT3 Signaling ENSG00000281324 ENSG00000272398 ENSG00000168610 ENSG00000115009 PMC6288499__F1 Epidermal growth factor receptor pathway in patients with wild-type and mutant BRAF and KRAS ENSG00000157764 ENSG00000146648 PMC8809363__F1 Recent Advances in the Role of Arid5a in Immune Diseases and Cancer ENSG00000196843 ENSG00000115415 ENSG00000136869 PMC6910185__F4 A diagram of mechanistic insight of genistein (Gen) to induce apoptosis in cancer cells ENSG00000149311 ENSG00000175054 ENSG00000213918 ENSG00000064393 ENSG00000125538 ENSG00000198793 ENSG00000159399 ENSG00000026103 PMC6910185__F5 Molecular targets of genistein (Gen) in cancer cell cycle ENSG00000149311 ENSG00000175054 ENSG00000148400 ENSG00000138798 ENSG00000123374 ENSG00000146648 PMC6910185__F6 Schematic representation of antiangiogenic activity of genistein (Gen) in cancer ENSG00000291971 ENSG00000198793 ENSG00000163914 ENSG00000168610 PMC6910185__F7 Illustration of antimetastatic potential of genistein (Gen) in cancer ENSG00000181019 ENSG00000178573 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000100985 ENSG00000150455 ENSG00000146648 PMC12185702__F2 Mapping of the multi-omics MAPK/OIS/SASP axis in pLGG cells ENSG00000182481 ENSG00000123240 ENSG00000002330 ENSG00000178999 ENSG00000165030 ENSG00000163739 ENSG00000169047 ENSG00000087586 ENSG00000205250 ENSG00000073111 ENSG00000162772 ENSG00000166851 ENSG00000128050 ENSG00000117713 ENSG00000103479 ENSG00000175054 ENSG00000175130 ENSG00000159216 ENSG00000198380 ENSG00000172216 ENSG00000172534 ENSG00000140379 ENSG00000149968 ENSG00000136997 ENSG00000004487 ENSG00000197386 ENSG00000185591 ENSG00000179348 ENSG00000140464 ENSG00000162889 ENSG00000122180 ENSG00000157764 ENSG00000148400 ENSG00000109320 ENSG00000173039 ENSG00000184481 ENSG00000149311 ENSG00000135446 ENSG00000177606 ENSG00000198517 ENSG00000135250 PMC5388758__F5 Gene networks associated with intestinal processes and diseases ENSG00000039537 ENSG00000113600 ENSG00000166278 ENSG00000127948 ENSG00000182326 ENSG00000069667 ENSG00000236625 PMC11765784__F2 Mechanism of amino acid signal sensing in PCa ENSG00000089154 ENSG00000128272 ENSG00000167992 PMC7035310__F3 Main anatomical connections—outputs and input pathways (shown as arrows) of the zona incerta ENSG00000090402 PMC4716033__F2 p21-activated kinase 4 signaling pathways in gastric cancer ENSG00000019991 ENSG00000087245 ENSG00000105329 ENSG00000138798 ENSG00000168036 ENSG00000146648 ENSG00000130669 PMC7946393__F1 Membrane trafficking regulation of primary cilium assembly in intracellular pathway ENSG00000013016 ENSG00000109113 ENSG00000169379 ENSG00000110274 ENSG00000099940 ENSG00000111737 ENSG00000138002 ENSG00000109083 ENSG00000112210 ENSG00000182504 ENSG00000164066 ENSG00000100629 ENSG00000198670 ENSG00000164953 PMC2901320__F5 CXCR4 pathway is affected in CD34+ cells from CAD patients ENSG00000010810 ENSG00000163914 ENSG00000168610 ENSG00000141968 ENSG00000121966 PMC7969034__F8 Working model of IFI16/p204 recognizing dsDNA to active downstream signaling pathway ENSG00000183735 ENSG00000163565 PMC6928971__F2 Overview of hedgehog signaling pathway ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC7564905__F1 Signaling mechanisms mediating the actions of neurotrophins ENSG00000002330 ENSG00000115415 ENSG00000150907 ENSG00000198793 ENSG00000136997 ENSG00000168610 PMC8397941__F3 Mechanistic Insight into the Effects of Curcumin on Neuroinflammation-Driven Chronic Pain ENSG00000168329 ENSG00000136869 PMC4689171__F2 IRAK4 inhibition to shut down TLR signaling in autoimmunity and MyD88-dependent lymphomas ENSG00000172936 ENSG00000184216 ENSG00000010671 ENSG00000198286 PMC11280978__F1 Mechanism of action by which MNPs cause neurotoxicity PMC3157841__F1 Expression Level Drives the Pattern of Selective Constraints along the Insulin/Tor Signal Transduction Pathway in Caenorhabditis ENSG00000118515 PMC8692646__F1 mTOR Signaling: The Interface Linking Cellular Metabolism and Hepatitis B Virus Replication ENSG00000177169 ENSG00000112561 PMC10862883__F5 Acceleration within PREs widely affects the Notch signaling pathway ENSG00000004975 ENSG00000135547 ENSG00000196591 ENSG00000196782 ENSG00000065717 ENSG00000138613 ENSG00000168214 ENSG00000074181 ENSG00000184384 ENSG00000283780 ENSG00000124232 ENSG00000196498 ENSG00000100603 ENSG00000107404 ENSG00000005339 ENSG00000138433 ENSG00000148400 ENSG00000100060 ENSG00000178498 ENSG00000184916 ENSG00000175029 ENSG00000135144 ENSG00000106003 ENSG00000091073 ENSG00000273529 ENSG00000133961 ENSG00000161202 ENSG00000114315 ENSG00000114166 PMC6328495__F1 The regulation of the mevalonate pathway and the role of mevalonate-derived metabolites in cell proliferation ENSG00000120942 ENSG00000113161 PMC6435658__F7 Illustration summarizes the molecular mechanism and signaling pathways underlying the effect of Dis on HCT-116 cells ENSG00000196591 ENSG00000181555 ENSG00000168040 ENSG00000125968 ENSG00000026103 ENSG00000108840 PMC4819171__F2 Transcriptome sequencing reveals e-cigarette vapor and mainstream-smoke from tobacco cigarettes activate different gene expression profiles in human bronchial epithelial cells ENSG00000087842 ENSG00000130159 ENSG00000127191 ENSG00000062485 PMC7912927__F1 PI3-K/Akt/mTOR signaling cascade ENSG00000198793 ENSG00000164327 PMC2866836__F1 Mitochondrial Ca2+ channels/transporters and role in mitochondrial function ENSG00000156026 PMC8212145__F4 Causal interactions from proteomic profiles: Molecular data meet pathway knowledge ENSG00000291971 ENSG00000163739 ENSG00000154639 ENSG00000198793 ENSG00000129514 ENSG00000180644 ENSG00000162302 ENSG00000135341 ENSG00000124762 ENSG00000171345 ENSG00000101680 ENSG00000241878 ENSG00000291944 ENSG00000012048 ENSG00000277571 ENSG00000175054 ENSG00000082175 ENSG00000157227 ENSG00000104320 ENSG00000263528 ENSG00000166501 ENSG00000168301 ENSG00000272398 ENSG00000167972 ENSG00000100219 ENSG00000139687 ENSG00000140464 ENSG00000253729 ENSG00000152495 ENSG00000160182 ENSG00000277804 ENSG00000073756 ENSG00000276561 ENSG00000160691 ENSG00000149311 ENSG00000177189 ENSG00000111537 ENSG00000102245 ENSG00000084090 ENSG00000100985 ENSG00000196208 ENSG00000073861 ENSG00000149503 PMC5796233__F1 Tumor progression toward cancer metastasis ENSG00000168036 ENSG00000162692 ENSG00000026103 PMC5796233__F2 Overview of anticancer properties of pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene; PS) ENSG00000168036 ENSG00000100985 ENSG00000146648 ENSG00000026103 PMC6821383__F1 Complement system and therapeutic targets in bacterial meningitis ENSG00000039537 ENSG00000113600 ENSG00000244731 ENSG00000166278 ENSG00000236625 PMC3259218__F1 Gemcitabine metabolic pathway genetic polymorphisms and response in non-small cell lung cancer patients ENSG00000048392 ENSG00000167325 ENSG00000171848 ENSG00000158825 ENSG00000112759 ENSG00000129187 PMC3147552__F8 Schematic overview of IDO induction by H ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000136869 PMC3833059__F7 Scheme of the proposed LIF signaling pathway in trophoblasts ENSG00000198793 ENSG00000128342 ENSG00000168610 PMC7793792__F1 Regulatory mechanisms of ferroptosis ENSG00000151012 ENSG00000167468 ENSG00000120733 ENSG00000142082 ENSG00000115107 ENSG00000057663 ENSG00000136381 PMC6543449__F2 IRFs in the TLR and IFN pathways ENSG00000159128 ENSG00000213928 ENSG00000239732 ENSG00000136869 ENSG00000168310 ENSG00000150455 ENSG00000125347 ENSG00000276561 ENSG00000164342 PMC9685675__F6 Roux-en-Y gastric bypass-induced perturbative changes in microbial communities and metabolic pathways in rats ENSG00000223802 ENSG00000188611 ENSG00000119537 ENSG00000168350 PMC8226792__F4 Comparison of Transcriptomic Profiles of MiaPaCa-2 Pancreatic Cancer Cells Treated with Different Statins ENSG00000002330 ENSG00000130396 ENSG00000070831 ENSG00000173039 ENSG00000141068 ENSG00000162924 ENSG00000213341 ENSG00000121879 ENSG00000100485 ENSG00000184481 ENSG00000108061 ENSG00000129219 ENSG00000157557 ENSG00000183735 ENSG00000017797 ENSG00000138193 ENSG00000112685 ENSG00000156299 ENSG00000276870 ENSG00000006451 ENSG00000126458 PMC3355325__F2 Two distinct DC semi-maturation pathways induce different types of regulatory T cells ENSG00000104856 ENSG00000168036 ENSG00000126353 PMC6819419__F1 Necroptosis molecular pathway ENSG00000137033 ENSG00000102871 ENSG00000189403 ENSG00000136869 ENSG00000168040 ENSG00000168404 ENSG00000285379 ENSG00000164342 PMC5295594__F2 Regulation of ecdysteroidogenesis PMC9289614__F1 Editorial: Autophagy-Mediated Cell Survival and Death in Disease Progression and Treatment ENSG00000177169 ENSG00000123395 ENSG00000126775 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC11016524__F2 Understanding PI3K/Akt/mTOR signaling in squamous cell carcinoma: mutated PIK3CA as an example ENSG00000166278 PMC2430503__F1 Resistance to ErbB-targeted cancer therapeutics ENSG00000169047 ENSG00000198793 PMC8212145__F5 Causal interactions from proteomic profiles: Molecular data meet pathway knowledge ENSG00000140992 ENSG00000002330 ENSG00000291971 ENSG00000050748 ENSG00000198793 ENSG00000168036 ENSG00000108443 ENSG00000164327 ENSG00000171791 ENSG00000179295 ENSG00000082175 ENSG00000166501 ENSG00000157764 ENSG00000065361 ENSG00000173039 ENSG00000018408 ENSG00000281877 ENSG00000132356 ENSG00000076555 ENSG00000168610 ENSG00000160691 ENSG00000065978 ENSG00000117020 ENSG00000134057 ENSG00000177606 ENSG00000105723 PMC9113527__F1 Enhancing HR Frequency for Precise Genome Editing in Plants ENSG00000051180 PMC3163779__F1 Thyroid hormone action is modulated by the deiodinases ENSG00000170893 PMC6567815__F2 Synthesis and function of NAD+ in the cytoplasm and nucleus ENSG00000105835 ENSG00000172890 PMC6567815__F3 Synthesis, metabolic pathways and function of acetyl-CoA ENSG00000131473 ENSG00000173599 ENSG00000096717 ENSG00000142082 ENSG00000026103 PMC11394240__F1 YAP/TAZ mechanisms in solid tumors, particularly HCCs, in hypoxic environments ENSG00000163914 ENSG00000198670 ENSG00000150457 ENSG00000131023 PMC11394240__F3 Phosphorylation of YAP/TAZ under hypoxic conditions ENSG00000089685 ENSG00000163914 ENSG00000113161 ENSG00000198670 ENSG00000196470 ENSG00000150457 ENSG00000131023 ENSG00000140443 PMC5711827__F1 Innate immune signaling pathways that drive type I IFN responses in mycobacteria-infected host cells ENSG00000183735 ENSG00000123576 ENSG00000164430 ENSG00000167207 ENSG00000136869 PMC5949009__F6 Schematic of accelerated tissue regeneration pathway via the dynamic and adaptive HMGB1–CXCL12–CXCR4–GAlert axis ENSG00000107562 ENSG00000189403 ENSG00000121966 PMC5628280__F1 Signal transduction by flagellin in mammalian cells ENSG00000187554 ENSG00000125538 ENSG00000136869 ENSG00000091106 ENSG00000175104 ENSG00000115009 PMC3130491__F4 Schematic of leptin intracellular signaling through the STAT3 and PI3K-PDE3B-cAMP pathways in the hypothalamus ENSG00000169047 ENSG00000115138 ENSG00000168610 PMC5933896__F3 Signaling and regulatory network of gp120 at apoptosis pathway ENSG00000158473 ENSG00000169896 ENSG00000088888 ENSG00000147168 ENSG00000086991 ENSG00000171049 ENSG00000164362 ENSG00000171791 ENSG00000171051 PMC7837452__F7 Iron-Sulfur Cluster Biogenesis, Trafficking, and Signaling: Roles for CGFS Glutaredoxins and BolA Proteins ENSG00000005194 ENSG00000103274 ENSG00000182511 ENSG00000188566 ENSG00000169627 PMC7837452__F5 Iron-Sulfur Cluster Biogenesis, Trafficking, and Signaling: Roles for CGFS Glutaredoxins and BolA Proteins ENSG00000169599 PMC5381815__F2 TAM Receptor Tyrosine Kinases as Emerging Targets of Innate Immune Checkpoint Blockade for Cancer Therapy ENSG00000115415 PMC8207720__F3 Functional interplay between long non-coding RNAs and the Wnt signaling cascade in osteosarcoma ENSG00000087245 ENSG00000134982 ENSG00000168036 ENSG00000253352 ENSG00000170242 ENSG00000096717 ENSG00000121966 PMC2864432__F3 Insulin/IGF1 signalling pathways and AD ENSG00000169291 ENSG00000002330 ENSG00000140443 PMC9156618__F2 Bioinformatics approach reveals the critical role of the NOD-like receptor signaling pathway in COVID-19-associated multiple sclerosis syndrome ENSG00000134460 ENSG00000187608 ENSG00000110799 ENSG00000180772 ENSG00000143839 ENSG00000126218 ENSG00000177455 ENSG00000281244 ENSG00000168214 ENSG00000169429 ENSG00000164400 ENSG00000136869 ENSG00000062485 ENSG00000108342 ENSG00000132356 ENSG00000188389 ENSG00000203747 ENSG00000169245 ENSG00000224320 ENSG00000179344 ENSG00000170458 ENSG00000118503 ENSG00000141086 ENSG00000213672 ENSG00000173692 ENSG00000168685 ENSG00000171855 ENSG00000162711 ENSG00000140564 ENSG00000198793 ENSG00000112715 ENSG00000164305 ENSG00000122194 ENSG00000010671 ENSG00000104368 ENSG00000180210 ENSG00000117525 ENSG00000103490 ENSG00000196549 ENSG00000130234 ENSG00000189403 ENSG00000037280 ENSG00000162747 ENSG00000104432 ENSG00000087116 ENSG00000116044 ENSG00000174358 ENSG00000111537 ENSG00000162409 ENSG00000005381 PMC8209414__F2 Molecular and Metabolic Reprogramming: Pulling the Strings Toward Tumor Metastasis ENSG00000180210 ENSG00000125166 ENSG00000135218 ENSG00000100033 ENSG00000070669 ENSG00000159399 PMC4178909__F1 The role of the VHL elongin BC complex in the HIF1 pathway in normoxic, hypoxic, and pseudohypoxic conditions ENSG00000134086 ENSG00000100387 ENSG00000154582 ENSG00000166266 PMC5180601__F6 Condition-specific dependency network (CDN) for indisulam for drug-sensitive cell lines ENSG00000134086 ENSG00000177606 ENSG00000112715 ENSG00000198363 PMC4545821__F5 2A-DNT on transcript expression, protein expression and nuclear signaling mapped onto the Kyoto Encyclopedia of Genes and Genomes (KEGG) peroxisome proliferator-activated receptor (PPAR) pathway ENSG00000150991 ENSG00000196839 ENSG00000100979 PMC4869267__F1 Scheme of glucose metabolism and the respiratory chain in Gluconobacter oxydans DSM2343 ENSG00000101751 ENSG00000166169 PMC9157768__F7 Extracellular Vesicles From Stored Red Blood Cells Convey Heme and Induce Spic Expression on Human Monocytes ENSG00000168329 ENSG00000136869 ENSG00000166211 ENSG00000156273 PMC8645845__F2 Novel Implications of MicroRNAs, Long Non-coding RNAs and Circular RNAs in Drug Resistance of Esophageal Cancer ENSG00000198914 ENSG00000148926 ENSG00000253352 PMC11673387__F6 LTA causes mammary gland injury in dairy cows ENSG00000226275 ENSG00000169710 ENSG00000073756 ENSG00000198911 PMC8233004__F5 Chemistry, Pharmacology and Therapeutic Potential of Swertiamarin – A Promising Natural Lead for New Drug Discovery and Development ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC9658666__F2 Pathways of Angiogenic and Inflammatory Cytokines in Multiple Myeloma: Role in Plasma Cell Clonal Expansion and Drug Resistance ENSG00000019991 ENSG00000125538 PMC3924254__F7 A6 integrin is the upstream regulator of the IGF-1R signaling pathway that enables low levels of caspase-3 activation to signal lens epithelial cell differentiation initiation ENSG00000291971 ENSG00000140443 PMC8350499__F1 Acetylation in doxorubicin-induced cardiotoxicity ENSG00000223573 ENSG00000094631 ENSG00000162711 ENSG00000115415 ENSG00000198793 ENSG00000096717 ENSG00000142082 ENSG00000168610 ENSG00000140443 PMC6085989__F1 Proposed model of host signaling cascade in response to microbial signals to promote hematopoiesis ENSG00000112977 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000106100 PMC4767455__F1 Role and mechanism of CRL4 E3 ubiquitin ligase in cancer and its potential therapy implications ENSG00000158290 ENSG00000134574 ENSG00000167986 ENSG00000139842 PMC3678929__F2 Insulin-like growth factor 1 receptor (IGF-1R) signaling pathway ENSG00000002330 ENSG00000169047 ENSG00000198793 ENSG00000105656 PMC10512581__F1 Hippo signaling pathway and therapeutic targets ENSG00000138071 ENSG00000105810 ENSG00000150457 ENSG00000131023 PMC8660125__F1 Regulation and Function of Interferon-Lambda (IFNλ) and Its Receptor in Asthma ENSG00000125347 ENSG00000175104 ENSG00000276561 ENSG00000164342 ENSG00000128536 PMC9613570__F2 Non-pharmacological interventions for vascular health and the role of the endothelium ENSG00000291971 ENSG00000127528 ENSG00000136826 ENSG00000103335 PMC3678929__F1 The insulin receptor (IR) with its two subtypes IR-A and IR-B, the insulin growth factor 1 receptor (IGF-1R) and the hybrid receptors (IGF-1R/IR-A and IGF-1R/IR-B) ENSG00000140443 PMC5423118__F8 Graphic summary ENSG00000167900 ENSG00000129187 PMC3092277__F1 Hippo signaling network in mammals ENSG00000126016 ENSG00000186575 ENSG00000150457 ENSG00000131023 ENSG00000169435 PMC6901313__F11 Conceptual framework of BCL-xL expression during persistent LPS senescence induction PMC7153214__F6 The mechanism ENSG00000168610 PMC10307880__F2 Viral-mimicry response induced by DNMTis ENSG00000183735 ENSG00000088888 ENSG00000276561 ENSG00000164342 PMC5414155__F7 Overall impact of ethanol stress on C ENSG00000144063 ENSG00000159224 PMC11642419__F2 PRV evades the TLR and RLR signaling pathways ENSG00000183735 ENSG00000239732 ENSG00000088888 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC7838829__F2 Going, Toll-like receptors in skin inflammation and inflammatory diseases ENSG00000170458 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC11642419__F3 PRV evades the DNA-sensing signaling pathway ENSG00000183735 ENSG00000164430 ENSG00000009335 ENSG00000163565 PMC5597247__F1 Transcriptional regulation of glycolytic and mitochondrial metabolism ENSG00000074800 ENSG00000136997 ENSG00000175567 ENSG00000168610 ENSG00000143995 PMC6470739__F2 Antioxidant signaling pathway regulated by quercetin ENSG00000178573 ENSG00000079999 PMC11642419__F4 PRV evades the IFNAR–JAK–STAT signaling pathway ENSG00000213928 ENSG00000187608 ENSG00000105397 ENSG00000157601 ENSG00000172183 PMC12213685__F12 HDH-SBH drug pair act on potential targets and mechanisms of action of PI3K/AKT signaling pathway ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000105401 ENSG00000186716 ENSG00000198793 ENSG00000169047 PMC8966870__F2 ILC2s can contribute to tumour rejection or tumour growth ENSG00000081041 ENSG00000139187 ENSG00000137033 ENSG00000169429 ENSG00000118520 PMC4325629__F1 Hedgehog signaling in cancer stem cells: a focus on hematological cancers ENSG00000106571 ENSG00000117425 ENSG00000164161 ENSG00000166813 ENSG00000128602 PMC4325629__F2 Hedgehog signaling in cancer stem cells: a focus on hematological cancers ENSG00000128602 PMC7838032__F3 The cyclin D–CDK4/6 complex ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC2818223__F2 GSK3 regulation of STATs, Smads, Beta-catenin, and NFAT ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000168610 PMC8185945__F9A In Parkinson's patient-derived dopamine neurons, the triplication of Alpha-synuclein locus induces distinctive firing pattern by impeding D2 receptor autoinhibition ENSG00000162889 ENSG00000140992 ENSG00000070831 ENSG00000291971 ENSG00000050748 ENSG00000130758 ENSG00000115904 ENSG00000127955 ENSG00000169032 ENSG00000149295 ENSG00000114738 ENSG00000160691 ENSG00000177606 ENSG00000124181 ENSG00000160293 ENSG00000165646 PMC9668345__F3 Alterations in the Salivary Proteome and N-Glycome of Sjögren’s Syndrome Patients ENSG00000172867 ENSG00000019991 ENSG00000186395 ENSG00000099985 ENSG00000100906 ENSG00000115415 ENSG00000108679 ENSG00000112715 ENSG00000140464 PMC3393825__F1 Signaling the Mitochondrial Unfolded Protein Response ENSG00000125656 ENSG00000106459 ENSG00000115317 PMC6646234__F10 MicroRNA-140-5p inhibits cell proliferation, migration and promotes cell apoptosis in gastric cancer through the negative regulation of THY1-mediated Notch signaling ENSG00000273529 ENSG00000114315 ENSG00000154096 PMC2516358__F7 Time ordered sequential events control cellular decision of migration ENSG00000019991 ENSG00000073756 ENSG00000073737 PMC3925720__F1 miR-22 in tumorigenesis ENSG00000136997 PMC7381748__F2 TPL2 signaling ENSG00000087245 ENSG00000163739 ENSG00000125538 ENSG00000177606 ENSG00000100985 ENSG00000168610 ENSG00000146648 ENSG00000131196 ENSG00000121966 ENSG00000101425 PMC7779757__F1 WNT pathaway signaling ENSG00000138795 ENSG00000100592 ENSG00000134982 ENSG00000102312 ENSG00000183579 ENSG00000168036 PMC3851544__F6 MT1G as a tumor suppressor in thyroid cancer cells through regulating the PI3K/Akt and Rb/E2F pathways.MT1G restoration inhibited phosphorylation of Akt, leading to inhibition of cell growth ENSG00000125144 PMC7751468__F6 Differentially expressed genes between normal mammary tissues and triple negative breast cancer tissues involved in PI3K/Akt signaling pathway based on the Kyoto Encyclopedia of Genes and Genomes analysis ENSG00000124102 ENSG00000065833 ENSG00000002330 ENSG00000186716 PMC9664868__F1 Dephospho-Coenzyme A Kinase Is an Exploitable Drug Target against Plasmodium falciparum: Identification of Selective Inhibitors by High-Throughput Screening of a Large Chemical Compound Library ENSG00000138621 ENSG00000127125 PMC1082717__F1 The mTOR pathway and the potential intersection with LMP2A-activated PI3-kinase/Akt signaling ENSG00000198793 ENSG00000136997 PMC5896702__F2 Biomarkers of resistance to immunotherapy ENSG00000089692 ENSG00000134982 PMC11929342__F5 Nrf2 as a target in ovary and ovarian dysfunctions focusing on its antioxidant properties ENSG00000079999 PMC12176563__F3 Multimodal regulation of cardiac metabolic flux and enzymatic hierarchy ENSG00000135218 ENSG00000147162 ENSG00000275544 PMC12176563__F4 Metabolic-targeted therapeutic interventions for cardiac functional recovery ENSG00000159224 ENSG00000197635 ENSG00000154059 ENSG00000096717 PMC8120183__F7 Cardamonin inhibits the progression of oesophageal cancer by inhibiting the PI3K/AKT signalling pathway ENSG00000002330 ENSG00000005882 ENSG00000170558 ENSG00000120868 PMC7103699__F1 Schematic representation to highlight the possible mechanism of action by which adjuvants exert their adjuvanticity ENSG00000164430 ENSG00000163568 ENSG00000150455 PMC4333386__F8 The functional interaction between RecQ helicases and the FA pathway ENSG00000197299 ENSG00000051180 PMC11398426__F7 Regulation of STING expression by CBFB/RUNXIn basal conditions, CBFB acts as a rheostat to fine-tune cGAS-STING pathway activity ENSG00000183735 ENSG00000134086 ENSG00000164430 PMC7901659__F1 Prostaglandin-Endoperoxide Synthase 2 (PTGS2) in the Oviduct: Roles in Fertilization and Early Embryo Development PMC3144045__F1 Signal pathway activation by different surface PRRs ENSG00000010704 ENSG00000187796 ENSG00000291971 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC3508273__F4 The role of tumor-associated macrophages (TAMs) during tumor angiogenesis PMC5385204__F6 Genomic alterations in malignant melanoma ENSG00000117020 ENSG00000128272 ENSG00000049130 ENSG00000182158 ENSG00000157764 ENSG00000101440 ENSG00000198793 ENSG00000136997 ENSG00000137203 ENSG00000087460 ENSG00000064300 PMC2783837__F2 TRAIL-R1/-R2 apoptotic signaling pathway ENSG00000168040 PMC6061042__F3 Tri-m-cresyl phosphate and PPAR/LXR interactions in seabream hepatocytes ENSG00000065833 ENSG00000134824 PMC4482087__F7 Rewired upstream transcription subnetwork in regulating the downstream pentose phosphate pathway in biomass conversion in Y-50049 yeast strain versus the wild-type ENSG00000288283 ENSG00000146909 ENSG00000158458 PMC7693814__F5 Illustration describing inflammation and apoptosis mechanisms in SARS-CoV-2 infection, suggesting similarity with those in Parkinson’s disease under oxidative stress ENSG00000105397 ENSG00000115415 ENSG00000130234 ENSG00000184012 ENSG00000168040 ENSG00000168610 PMC5167405__F8 Non-Canonical Role of IKKA in the Regulation of STAT1 Phosphorylation in Antiviral Signaling ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000115415 PMC7554875__F1 NFKB and MAPK pathways ENSG00000172936 ENSG00000167182 ENSG00000184216 PMC4066980__F4 Model for Id1 regulation of melanocyte growth and melanoma development ENSG00000048162 ENSG00000157764 ENSG00000125968 PMC5791865__F1 Impact of MK2- and IKK-dependent phosphorylation on RIPK1 function ENSG00000137275 ENSG00000168040 ENSG00000064012 PMC7241659__F1 Cellular metabolism during T cells activation ENSG00000135218 ENSG00000198793 ENSG00000136997 PMC8363725__F6 The biosynthesis of the nemamides ENSG00000291560 ENSG00000174788 ENSG00000166278 PMC12150591__F2 Oxidative stress plays a dual role in CRC development ENSG00000134982 ENSG00000168036 PMC6469615__F2 Proposed metabolic pathway for shea butter biosynthesis adapted from Argout et al ENSG00000173599 ENSG00000158669 ENSG00000198670 PMC4482087__F6 Rewired transcription network regulating metabolic pathways for tolerant industrial yeast Saccharomyces cerevisiae NRRL Y-50049 ENSG00000069482 ENSG00000184232 ENSG00000158458 PMC12150591__F3 Differential regulation of oxidative stress and cell death by wild-type and mutant p53 ENSG00000198793 ENSG00000086991 ENSG00000175567 PMC12150591__F4 Oncogenic roles of KRAS and BRAF mutations in CRC development, malignant transformation, and metastasis ENSG00000140992 ENSG00000157764 PMC4610744__F1 Genes and pathways identified from GWAS and/or studies of monogenic allergy-related diseases ENSG00000174123 ENSG00000174125 ENSG00000133710 ENSG00000137033 ENSG00000123411 ENSG00000237165 ENSG00000129514 ENSG00000145777 ENSG00000134760 ENSG00000172818 ENSG00000049768 ENSG00000168610 ENSG00000143631 ENSG00000069667 ENSG00000115602 ENSG00000100385 ENSG00000136997 ENSG00000015285 ENSG00000137507 ENSG00000197943 ENSG00000107485 ENSG00000128536 ENSG00000013375 PMC7958998__F2 From genetics to pharmacological treatment.Notes: Bone morphogenetic protein receptor II, BMPR-II; BMP-responsive element, BRE; Caveolin-1, CAV1; 12-kDa FK506-binding protein, FKBP12 ENSG00000170365 ENSG00000204217 ENSG00000171303 PMC6201690__F1 Overview scheme of the PD risk factor genes and the molecular pathway where they are involved ENSG00000100225 ENSG00000109743 ENSG00000103510 ENSG00000119899 ENSG00000078070 ENSG00000158828 ENSG00000069329 ENSG00000127419 ENSG00000138760 ENSG00000167186 PMC10152798__F5 HDAC inhibitors on neuroblastoma SH-SY5Y cell differentiation into mature neurons via the Wnt signaling pathway ENSG00000162552 PMC3464266__F3 Insights into Pancreatic Cancer Etiology from Pathway Analysis of Genome-Wide Association Study Data ENSG00000147432 ENSG00000140795 ENSG00000175398 ENSG00000136839 ENSG00000196772 ENSG00000171596 ENSG00000122859 ENSG00000163285 ENSG00000204246 ENSG00000186881 ENSG00000117020 ENSG00000127533 ENSG00000110148 ENSG00000145649 ENSG00000082556 ENSG00000151617 PMC4390253__F1 Construction of the Golgi/endosome network (GEN) and of the IR subnetwork (IRGEN) ENSG00000130300 ENSG00000182718 ENSG00000111057 ENSG00000171105 ENSG00000110244 ENSG00000168036 ENSG00000120885 ENSG00000079432 ENSG00000076555 ENSG00000132356 ENSG00000132693 ENSG00000113441 ENSG00000115290 ENSG00000215021 ENSG00000114349 ENSG00000150991 ENSG00000137364 ENSG00000004455 ENSG00000005893 ENSG00000155980 ENSG00000130175 ENSG00000116761 ENSG00000084774 ENSG00000162896 PMC8698340__F2 Peripheral Cytokine Levels as a Prognostic Indicator in Gastric Cancer: A Review of Existing Literature ENSG00000149269 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC7940388__F6 Signaling pathway mediated by CBD in SH-SY5Y cells ENSG00000177169 ENSG00000083290 ENSG00000198793 ENSG00000196689 PMC3817717__F2 Ingenuity Pathway Analysis (Ingenuity Systems, Inc., Redwood City, CA) of endothelial gene expression ENSG00000049323 ENSG00000110330 ENSG00000198053 ENSG00000175220 ENSG00000148926 ENSG00000112530 ENSG00000166886 ENSG00000122194 ENSG00000104368 ENSG00000136807 ENSG00000245848 ENSG00000170365 ENSG00000178607 ENSG00000263528 ENSG00000136997 ENSG00000185591 ENSG00000100219 ENSG00000142627 ENSG00000143549 ENSG00000165119 ENSG00000095059 ENSG00000140416 ENSG00000149311 ENSG00000128872 ENSG00000185883 ENSG00000124570 ENSG00000100280 ENSG00000143514 ENSG00000077232 ENSG00000058262 ENSG00000116106 ENSG00000198176 ENSG00000177606 ENSG00000184436 ENSG00000015285 ENSG00000113758 ENSG00000175104 PMC8855225__F1 Gli Phosphorylation Code in Hedgehog Signal Transduction ENSG00000143147 ENSG00000166813 ENSG00000128602 ENSG00000124253 PMC6660363__F2 Serum Proteomics Based Discovery Of Predictive Biomarkers Of Response To Androgen Deprivation Therapy In Advanced Prostate Cancer ENSG00000105329 ENSG00000110244 ENSG00000167768 ENSG00000162267 ENSG00000081051 ENSG00000168610 ENSG00000291973 ENSG00000105664 ENSG00000132196 ENSG00000145192 ENSG00000123933 ENSG00000198670 ENSG00000174106 ENSG00000117983 ENSG00000162896 PMC5660951__F7 Suggested mechanism of EtSCT action in CCl4-induced hepatic injury ENSG00000087245 ENSG00000100985 PMC9127077__F1 C-Type Lectin Receptor Signaling in the Intestinal Microbiota-Inflammation-Cancer Axis ENSG00000081041 ENSG00000187796 ENSG00000168036 ENSG00000168610 ENSG00000106546 PMC8585084__F3 Autophagy Regulation by Crosstalk between miRNAs and Ubiquitination System ENSG00000135655 ENSG00000177169 ENSG00000152348 ENSG00000108395 ENSG00000126775 ENSG00000148400 ENSG00000141569 ENSG00000057663 ENSG00000162298 ENSG00000069869 ENSG00000144848 ENSG00000175104 ENSG00000096717 ENSG00000145782 PMC4115639__F4 Cartoon depicts IL-15 mediated activation of the PI3K/ERK1/2 and JAK1/STAT3 pathways ENSG00000100385 ENSG00000168610 PMC3681701__F9 Sources of sphingolipids for the parasite ENSG00000172780 ENSG00000119396 ENSG00000102172 PMC4226052__F6 Up-regulation of the type I IFN canonical pathway by IFNB treatment ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000185745 ENSG00000230034 PMC8463267__F10 Combination therapy with miR34a and doxorubicin synergistically inhibits Dox-resistant breast cancer progression via down-regulation of Snail through suppressing Notch/NFKB and RAS/RAF/MEK/ERK signaling pathway ENSG00000170558 ENSG00000026508 PMC3822007__F1 New developments in the Induction and Antiviral Effectors of Type I Interferon ENSG00000183735 ENSG00000168036 ENSG00000131323 PMC6801420__F5 Pathway signaling network generated from the genes located within the top 100 most differentially methylated CpG islands ENSG00000033327 ENSG00000157933 ENSG00000134982 ENSG00000291971 ENSG00000169047 ENSG00000141968 ENSG00000122025 ENSG00000148082 ENSG00000147869 ENSG00000170430 ENSG00000078674 ENSG00000120656 ENSG00000157540 ENSG00000149091 ENSG00000087460 ENSG00000074219 ENSG00000129911 ENSG00000225950 ENSG00000160691 ENSG00000110395 ENSG00000178188 ENSG00000130382 ENSG00000107854 ENSG00000177606 ENSG00000146216 ENSG00000198576 ENSG00000157450 ENSG00000128602 ENSG00000134909 ENSG00000130669 ENSG00000173273 PMC3925679__F2 Bile Acid Receptors in Non-alcoholic Fatty Liver Disease ENSG00000130164 ENSG00000042832 ENSG00000105550 ENSG00000132855 ENSG00000169174 PMC7670427__F3 EIF2 pathway overlay with the experimental data, AD detection and molecules activation prediction (MAP) ENSG00000144895 ENSG00000086991 ENSG00000162772 PMC8015775__F11 Proposed model for a role of BANK1 in tolerant patients ENSG00000186716 ENSG00000153064 ENSG00000168040 ENSG00000175104 ENSG00000026103 PMC7946832__F1 Complement cascade and key canonical and non-canonical activities ENSG00000198793 ENSG00000117335 ENSG00000166278 PMC6517507__F1 Model suggesting the relationships between Th17, Th1* and cTh1 populations and their potential roles in post-vaccination immunity, LTBI and active TB ENSG00000186810 ENSG00000125538 ENSG00000112486 PMC6008051__F5 Network interactions of transcription factors predicted to be upstream of differentially expressed skeletal muscle genes ENSG00000101470 ENSG00000168036 ENSG00000101306 ENSG00000129152 ENSG00000112715 ENSG00000139687 ENSG00000127616 PMC4966488__F1 Viral oncolysis dependent on RNA-activated protein kinase (PKR) inactivation ENSG00000144895 ENSG00000168040 ENSG00000168610 PMC6356359__F6 Proposed epigenetic model of colonic inflammation and carcinogenesis associated with long-term exposure to a diet high in n-6 fatty acids (n-6HFD) ENSG00000134982 ENSG00000168036 PMC9629042__F2 Ultrasensitive chemiluminescent neuraminidase probe for rapid screening and identification of small-molecules with antiviral activity against influenza A virus in mammalian cells ENSG00000127948 PMC3631177__F2 Expression of Glyceraldehyde-3-Phosphate Dehydrogenase Associated Cell Cycle (GACC) Genes Correlates with Cancer Stage and Poor Survival in Patients with Solid Tumors PMC8960167__F1 Application of Regulatory Cell Death in Cancer: Based on Targeted Therapy and Immunotherapy ENSG00000278718 ENSG00000120868 ENSG00000083799 ENSG00000168404 ENSG00000026103 PMC8960167__F2 Application of Regulatory Cell Death in Cancer: Based on Targeted Therapy and Immunotherapy ENSG00000143799 ENSG00000161905 ENSG00000116044 ENSG00000151012 ENSG00000156709 ENSG00000167468 ENSG00000111684 PMC5964334__F6 Proposed model of an energy balance-responsive network associated with DNMT1 regulation, DNA methylation and transcriptional regulation of ERA and ERB ENSG00000239732 ENSG00000138798 ENSG00000125538 ENSG00000169047 ENSG00000168610 ENSG00000146648 ENSG00000140443 PMC4002811__F2 Peli1 mediates IKK activation by the TRIF-dependent TLR pathway ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000174516 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC3268129__F1 Amidoligases with ATP-grasp, glutamine synthetase-like and acetyltransferase-like domains: synthesis of novel metabolites and peptide modifications of proteins ENSG00000154016 ENSG00000114999 PMC7869004__F6 Drug target prediction and repurposing“Waterdrop” diagrams showing drug-target ENSG00000198793 ENSG00000132639 ENSG00000115419 PMC8664259__F7 Role of TAF7 in linking transcription and translation ENSG00000178913 ENSG00000141867 ENSG00000147133 ENSG00000167074 PMC5474130__F2 Oxysterols in human cancer ENSG00000110048 PMC6645245__F11 Schematic diagram representing possible antifungal mechanism (a–e) of CIN and EUG in C ENSG00000157554 ENSG00000067064 PMC9329358__F1 Molecular mechanism of pyroptosis ENSG00000278718 ENSG00000145649 ENSG00000189403 ENSG00000147697 ENSG00000073605 PMC4689482__F2 ARID1A mutation and anticancer agents on the PI3K/AKT pathway ENSG00000117713 ENSG00000157764 ENSG00000198793 PMC3494084__F4 Baculovirus infection impact on host cell metabolism ENSG00000122966 ENSG00000172005 ENSG00000062485 PMC5902007__F1 The gut microbiota in health and MS ENSG00000049768 PMC11638311__F4 Metabolic pathway of sphingolipids ENSG00000139624 ENSG00000100422 ENSG00000063176 ENSG00000223802 ENSG00000100596 ENSG00000154227 ENSG00000143753 ENSG00000165389 ENSG00000285281 ENSG00000168350 ENSG00000143418 ENSG00000163082 PMC11531110__F8 Metabolic pathway analysis and metabolite-protein interaction networks in broiler chickens challenged with CP and its different toxin combinations ENSG00000154059 PMC11531110__F9 Integrated metabolic pathway network analysis in NE-affected jejunal tissues ENSG00000081181 ENSG00000173599 ENSG00000059573 ENSG00000007171 ENSG00000062485 PMC10136970__F3 Pan-pathway inhibition ENSG00000135446 ENSG00000138798 ENSG00000105810 ENSG00000146648 PMC6678315__F2 Activation of c-Rel signaling by the canonical NFKB pathway in B cells ENSG00000186716 ENSG00000197943 ENSG00000010671 PMC8257365__F1 Dietary Antioxidants in p53-Mediated Cancer Chemoprevention and Tumor Suppression ENSG00000112378 PMC5838194__F3 Gene ontology enrichment of relate 16 key genes to the PPI network of NAFLD rat after fat diet feeding is presented ENSG00000131473 ENSG00000291971 ENSG00000076555 ENSG00000104325 ENSG00000163631 PMC10419059__F3 Wnt/Beta-catenin signalling pathway ENSG00000281324 ENSG00000162337 ENSG00000134569 ENSG00000134982 ENSG00000155011 ENSG00000168036 ENSG00000104332 PMC10419059__F2 Insulin and IGF-1 signalling pathway ENSG00000140443 PMC7711884__F1 Graphic scheme of the genes involved in the adsorption, distribution, metabolism and excretion (ADME) of fluoropyrimidines ENSG00000172831 ENSG00000188641 ENSG00000255974 ENSG00000167900 ENSG00000118777 ENSG00000114770 ENSG00000137204 ENSG00000167325 ENSG00000171848 ENSG00000158825 ENSG00000147647 ENSG00000112759 ENSG00000143179 ENSG00000262243 PMC3179949__F6 A schematic representation showing 17Beta-estradiol inhibition of uPA and MMP-9 expression, and cell motility via suppression of JNK1/2 pathway in human LoVo colon cancer cells ENSG00000100234 ENSG00000291631 PMC6266080__F4 LPL pathway and associated proteins ENSG00000103227 ENSG00000277494 ENSG00000167772 ENSG00000132855 PMC9511810__F2 Base excision repair accessory factors in senescence avoidance and resistance to treatments ENSG00000111249 ENSG00000182568 ENSG00000086991 ENSG00000196712 ENSG00000079999 PMC4370285__F8 Schematic model of EGFR stabilization by cigarette smoke ENSG00000138798 ENSG00000146648 PMC8174805__F1 Disparate roles of retinoid acid signaling molecules in kidney disease ENSG00000121207 PMC4381776__F1 One-carbon metabolism in the cytoplasm and nucleus ENSG00000228716 ENSG00000167900 ENSG00000116984 PMC4889059__F2 Association of Metabolites with Obesity and Type 2 Diabetes Based on FTO Genotype ENSG00000198793 ENSG00000173599 PMC8961234__F4 Unraveling the regulation of sugar beet pulp utilization in the industrially relevant fungus Aspergillus niger ENSG00000174429 PMC10523725__F7 Gut metabolite 3-hydroxyphenylacetic acid rejuvenates spermatogenic dysfunction in aged mice through GPX4-mediated ferroptosis ENSG00000168003 ENSG00000151012 ENSG00000167468 PMC2577794__F1 Uncovering cryptic genetic variation in C ENSG00000138798 ENSG00000137845 ENSG00000146648 PMC6098952__F1 Schematic representation for the possible interaction of viral oncogene proteins with various levels of Wnt/Beta-catenin cell signaling cascade ENSG00000281324 ENSG00000162337 ENSG00000291971 ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000196470 PMC5901897__F2 MEK5-ERK5 Signaling in Cancer: Implications for Targeted Therapy ENSG00000168610 ENSG00000140464 PMC5541270__F8 Proposed mechanistic scheme of MUC13 regulating NFKB activation, related to , , and ENSG00000143799 ENSG00000149311 ENSG00000102871 ENSG00000175104 ENSG00000173702 PMC12119701__F8 Possible mechanism underlying KCTD1-enhanced HCC progression ENSG00000198793 ENSG00000134504 PMC6082822__F1 Autoimmune Responses in Severe Asthma ENSG00000134982 ENSG00000137077 ENSG00000102970 ENSG00000105656 ENSG00000005381 ENSG00000121053 PMC8375270__F1 When Viruses Cross Developmental Pathways ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC4946912__F7 Network of transcriptional regulation and ligand receptor signaling ENSG00000010803 ENSG00000128016 ENSG00000163739 ENSG00000159259 ENSG00000122877 ENSG00000095585 ENSG00000066044 ENSG00000111341 ENSG00000143333 ENSG00000025293 ENSG00000135097 ENSG00000109133 ENSG00000119669 ENSG00000173156 ENSG00000180787 ENSG00000116717 ENSG00000125347 ENSG00000168610 ENSG00000006007 ENSG00000170458 ENSG00000131668 ENSG00000105982 ENSG00000186834 ENSG00000196372 ENSG00000144339 ENSG00000152291 ENSG00000128714 ENSG00000128965 PMC5226473__F1 CDK4/6 inhibition: the late harvest cycle begins ENSG00000135446 ENSG00000198793 ENSG00000146648 PMC8375270__F2 When Viruses Cross Developmental Pathways ENSG00000148400 ENSG00000074181 PMC10237620__F1 MTOR signaling pathway in cardiac aging ENSG00000177169 ENSG00000198793 ENSG00000163914 ENSG00000118515 ENSG00000155792 ENSG00000158828 ENSG00000167965 PMC4007103__F2 Biogenesis of Drosophila small regulatory RNAs ENSG00000092847 ENSG00000113360 ENSG00000123908 PMC128142__F1 Proposed biosynthetic pathway of GPI in the ER of P ENSG00000069943 ENSG00000159224 ENSG00000143315 PMC7713543__F2 SARS-CoV-2 Replication and Interaction with Host Cells(A) Simplified schematic of the viral replication cycle ENSG00000088888 ENSG00000130234 ENSG00000184012 ENSG00000164342 PMC8375270__F5 When Viruses Cross Developmental Pathways ENSG00000188290 ENSG00000128917 ENSG00000173673 ENSG00000069812 ENSG00000168036 ENSG00000164690 ENSG00000273529 ENSG00000114315 ENSG00000128602 ENSG00000163501 ENSG00000155760 ENSG00000109670 PMC4147239__F1 MTOR signaling pathway ENSG00000169047 PMC9436908__F2 Modulatory effect of high salt on immune cells and related diseases ENSG00000162711 ENSG00000102908 ENSG00000198793 ENSG00000137265 ENSG00000091106 ENSG00000118520 PMC11979251__F2 Immunogenic cell death (ICD) induced by epigenetic modifiers of DNA methyltransferase, histone deacetylase and proteasome inhibitors ENSG00000169245 ENSG00000171720 ENSG00000189403 ENSG00000100219 ENSG00000114383 PMC5061805__F1 Fast action antidepressants activate mTOR ENSG00000198793 ENSG00000284161 PMC11979251__F3 Molecular mechanisms of immunogenic cell death (ICD) related to reactive oxygen species (ROS) production and endoplasmic reticulum (ER) stress ENSG00000128272 ENSG00000185591 PMC5061805__F2 Mechanisms involved in the delay of therapeutic response to classic antidepressants in MDD patients ENSG00000198793 ENSG00000284161 PMC11979251__F6 Crosstalk between immunogenic cell death (ICD) and different intracellular signaling pathways of nuclear factor kappa-B (NFKB), stimulator of interferon genes (STING), and mitogen-activated protein kinase (MAPK) ENSG00000183735 ENSG00000189403 PMC4856820__F3 Schematic picture demonstrating the myogenesis pathway and the myogenic regulatory genes (highlight in red color) identified in beltfish muscle transcriptome ENSG00000009709 ENSG00000111049 ENSG00000135903 PMC3755473__F1 Plasma Cells For Hire: Prior Experience Required ENSG00000198793 ENSG00000112182 PMC9363660__F1 Onco-immunomodulatory properties of pharmacological interference with RAS-RAF-MEK-ERK pathway hyperactivation ENSG00000111537 ENSG00000186716 PMC1316260__F6 Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway ENSG00000169291 ENSG00000138798 ENSG00000124181 PMC7803547__F2 CD8+ T-cell metabolism in COVID-19 ENSG00000134982 ENSG00000125538 ENSG00000198793 ENSG00000079999 PMC4696838__F2 MSCs reduce a central profibrotic factor, TGFB1, using STC1 in bleomycin-induced pulmonary fibrosis ENSG00000124102 ENSG00000198793 ENSG00000197299 ENSG00000175567 PMC7666630__F4 Constructed ceRNA networks based on the selected vital genes related to the MAPK signaling pathway: (a) the circRNA-miRNA-mRNA network and (b) lncRNA-miRNA-mRNA network ENSG00000138166 ENSG00000143507 ENSG00000291431 ENSG00000177606 ENSG00000130222 ENSG00000099860 ENSG00000158050 PMC3658475__F2 P53/MDM2 regulation ENSG00000149311 ENSG00000175054 ENSG00000026103 PMC7784881__F1 CD5 and B lymphocyte responses: multifaceted effects through multitudes of pathways and channels ENSG00000110448 ENSG00000186716 ENSG00000198793 ENSG00000197943 PMC2846071__F1 Prevention trumps treatment of antibody-mediated transplant rejection ENSG00000186716 PMC5642988__F1 Hippo pathway in intestinal regeneration and disease ENSG00000126016 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC4174460__F1 Seven FDA-approved agents for the treatment of kidney cancer targeting the von Hippel–Lindau (VHL) tumour suppressor pathway ENSG00000134086 ENSG00000163235 ENSG00000198793 ENSG00000146648 PMC5642988__F4 Hippo pathway in intestinal regeneration and disease ENSG00000146648 PMC2276649__F8 GSK-3B Targets Cdc25A for Ubiquitin-Mediated Proteolysis and GSK-3B Inactivation Correlates with Cdc25A Overproduction in Human Cancers ENSG00000149311 ENSG00000175054 PMC11975862__F7 Active ingredient–shared target–pathway network analysis ENSG00000129214 ENSG00000143839 PMC5642988__F5 Hippo pathway in intestinal regeneration and disease ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC3565315__F1 Overview of the Hedgehog signaling pathway: a simplified model for Hh signaling in mammalian cells ENSG00000166813 ENSG00000128602 PMC5642988__F2 The Hippo pathway in intestinal regeneration and disease ENSG00000146648 PMC5638134__F6 Chloroformate Derivatization for Tracing the Fate of Amino Acids in Cells and Tissues by Multiple Stable Isotope Resolved Metabolomics (mSIRM) ENSG00000284320 ENSG00000065911 ENSG00000092621 ENSG00000135069 ENSG00000178445 PMC5642988__F6 Hippo pathway in intestinal regeneration and disease ENSG00000114978 ENSG00000150457 ENSG00000131023 PMC3565315__F2 Overview about currently tested Hedgehog pathway inhibitors and their mode of action ENSG00000166813 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC8961445__F2 Molecular Mechanisms Driving IL-10- Producing B Cells Functions: STAT3 and c-MAF as Underestimated Central Key Regulators? ENSG00000239732 ENSG00000186716 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC8433626__F5 Protein C-Mannosylation and C-Mannosyl Tryptophan in Chemical Biology and Medicine ENSG00000000419 ENSG00000136908 PMC8611677__F5 Cortical Transcriptomic Alterations in Association With Appetitive Neuropeptides and Body Mass Index in Posttraumatic Stress Disorder ENSG00000157554 ENSG00000123146 ENSG00000164129 ENSG00000182687 ENSG00000183853 ENSG00000146425 ENSG00000244165 ENSG00000291971 ENSG00000169860 ENSG00000135245 ENSG00000171596 ENSG00000134245 ENSG00000213694 ENSG00000204174 ENSG00000263310 ENSG00000100625 ENSG00000134686 ENSG00000127507 PMC10466072__F9 Schematic diagram ENSG00000068028 ENSG00000135446 ENSG00000105810 ENSG00000150457 ENSG00000131023 PMC6826584__F5 Notch signaling pathway by ubiqutination upon binding of Jagged/Delta (JAG/DLL) ligands to the Notch receptor (N1); the endocytic system is activated in the ligand-bearing cell ENSG00000148400 ENSG00000138798 ENSG00000137845 ENSG00000090932 ENSG00000112130 ENSG00000069869 ENSG00000197530 ENSG00000283780 ENSG00000078747 ENSG00000139517 ENSG00000133961 ENSG00000114315 ENSG00000101752 ENSG00000109670 PMC7150840__F1 Simplified scheme of the Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000168036 PMC5552414__F7 Abl Kinase Regulation by BRAF/ERK and Cooperation with Akt in Melanoma ENSG00000122691 ENSG00000168610 PMC7150840__F2 FGF23/Klotho interactions with the Wnt/Beta-catenin pathway in the bone, kidney, and heart ENSG00000118972 ENSG00000168036 ENSG00000077782 PMC2843459__F11 Schematic diagram illustrating the proposed signaling pathway involved in LTA-induced cPLA2/COX-2–dependent airway inflammation ENSG00000226275 ENSG00000172936 PMC9363660__F3 Onco-immunomodulatory properties of pharmacological interference with RAS-RAF-MEK-ERK pathway hyperactivation ENSG00000111537 PMC6826584__F3 Wnt signaling pathway and its regulation by ubiquitination The canonical Wnt signaling pathway is triggered by Wnt ligand binding to the complex of its receptor, Frizzled, and co-receptors LRP5/6 ENSG00000118518 ENSG00000181788 ENSG00000117153 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000196470 ENSG00000078747 ENSG00000198742 ENSG00000113558 ENSG00000156427 ENSG00000136997 ENSG00000183579 ENSG00000108375 PMC6826584__F4 TGFB signaling pathway and its regulation by ubiqutination TGFB released from the LTBP1 complex binds to TGFB receptor II (TGFBRII) and initiates transphosphorylation and activation of the associated TGFB receptor I (TGFBRI) ENSG00000145604 ENSG00000049323 ENSG00000005810 ENSG00000133937 ENSG00000185155 ENSG00000078747 ENSG00000198742 ENSG00000123124 ENSG00000185104 PMC4145234__F1 Regulatory networks of miRNAs and PI3K/AKT pathway in controlling EMT and cancer stemness in human tumors including endometrial cancer ENSG00000122691 ENSG00000198793 PMC8863680__F2 Detailed Overview of Immune Escape, Antibody Escape, Partial Vaccine Escape of SARS-CoV-2 and Their Emerging Variants With Escape Mutations ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 PMC7272579__F5 KEGG database pathway hsa05200: pathways in cancer ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000122008 PMC9022632__F2 Biology and Clinical Relevance of HCMV-Associated Adaptive NK Cells PMC6298254__F3 Protein-protein interaction map of the TNF-induced NFKB signal transduction pathway ENSG00000228716 ENSG00000123240 ENSG00000148481 ENSG00000102871 ENSG00000075975 ENSG00000135451 ENSG00000174799 ENSG00000219545 ENSG00000175455 ENSG00000166025 ENSG00000164221 ENSG00000265491 ENSG00000198056 ENSG00000079931 ENSG00000185236 ENSG00000153140 ENSG00000180667 ENSG00000088888 ENSG00000107130 ENSG00000082512 ENSG00000084652 ENSG00000090615 ENSG00000056558 ENSG00000155760 ENSG00000064012 ENSG00000126016 ENSG00000173376 ENSG00000168040 ENSG00000127191 ENSG00000291420 ENSG00000267534 ENSG00000076604 ENSG00000131019 ENSG00000115415 ENSG00000139517 ENSG00000131323 ENSG00000083799 ENSG00000123595 ENSG00000121060 PMC3865046__F1 Proteasome-dependent degradation of replisome components regulates faithful DNA replication ENSG00000175054 ENSG00000164053 ENSG00000111602 ENSG00000163624 ENSG00000260314 ENSG00000100387 ENSG00000132646 ENSG00000113558 PMC12066772__F16 The mechanism by which Iso inhibits RANKL-induced osteoclastogenesis ENSG00000100985 ENSG00000175104 ENSG00000131196 ENSG00000143387 PMC8775422__F4 Pathophysiology of Mild Hypercortisolism: From the Bench to the Bedside ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4766428__F2 Bacterial cellulose synthesis mechanism of facultative anaerobe Enterobacter sp. FY-07 ENSG00000171540 ENSG00000026103 PMC6298254__F1 Protein-protein interaction map of the TNF-induced NFKB signal transduction pathway ENSG00000123091 ENSG00000078747 ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000154124 ENSG00000127191 ENSG00000064012 PMC10518103__F9 DSCC1 interacts with HSP90AB1 and promotes the progression of lung adenocarcinoma via regulating ER stress ENSG00000136982 ENSG00000168610 PMC4979363__F6 Proposed mechanism of Hb (and its oxidized species)-induced toxicity: Hb undergoes oxidation to higher oxidation states, such as HbFe3+ and HbFe4+ ENSG00000180210 ENSG00000136869 PMC2762009__F1 The Tripartite Glutamatergic Synapse in the Pathophysiology and Therapeutics of Mood Disorders ENSG00000196531 PMC8468657__F3 Iterative Upgrading of Small Molecular Tyrosine Kinase Inhibitors for EGFR Mutation in NSCLC: Necessity and Perspective ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC2849853__F5 Regulation of the Hypothalamic Thyrotropin Releasing Hormone (TRH) Neuron by Neuronal and Peripheral Inputs ENSG00000198576 ENSG00000166603 PMC3788099__F7 Association between Inflammatory Infiltrates and Isolated Monosomy 22/del(22q) in Meningiomas ENSG00000033327 ENSG00000011600 ENSG00000134982 ENSG00000150337 ENSG00000187764 ENSG00000171791 ENSG00000143226 ENSG00000116815 ENSG00000125538 ENSG00000277263 ENSG00000125810 ENSG00000197081 ENSG00000081237 ENSG00000140968 ENSG00000137070 ENSG00000110324 ENSG00000177663 ENSG00000203747 ENSG00000019582 ENSG00000170458 ENSG00000187554 ENSG00000015285 ENSG00000026508 ENSG00000172936 ENSG00000162692 ENSG00000038945 PMC4747886__F4 Molecular mechanisms of survivin in tumorigenesis ENSG00000135446 ENSG00000168036 ENSG00000168610 PMC7522266__F2 Bifidobacterium longum subsp PMC9524955__F7 Study on the mechanism of warming yang and reducing turbidity decoction in the treatment of diabetic kidney disease based on network pharmacology ENSG00000127445 ENSG00000150907 ENSG00000007908 PMC7843730__F2 Mechanistic dissection of diabetic retinopathy using the protein-metabolite interactome ENSG00000070831 ENSG00000044115 ENSG00000163629 ENSG00000134982 ENSG00000168036 ENSG00000010278 ENSG00000167653 ENSG00000121879 ENSG00000131126 ENSG00000196586 ENSG00000173621 ENSG00000205442 ENSG00000099840 ENSG00000150556 ENSG00000118434 ENSG00000184986 ENSG00000274488 ENSG00000075884 ENSG00000215915 ENSG00000169499 ENSG00000161652 ENSG00000291874 ENSG00000160886 ENSG00000162836 ENSG00000065361 ENSG00000109321 ENSG00000166862 ENSG00000156564 ENSG00000148660 ENSG00000163235 ENSG00000125675 ENSG00000188130 ENSG00000146648 ENSG00000145349 PMC7843730__F5 Mechanistic dissection of diabetic retinopathy using the protein-metabolite interactome ENSG00000121552 ENSG00000196839 ENSG00000015285 ENSG00000154016 ENSG00000127948 ENSG00000143669 PMC8258133__F2 Emerging Potential of Exosomes on Adipogenic Differentiation of Mesenchymal Stem Cells ENSG00000178860 ENSG00000142611 PMC3664143__F1 A Novel High-Throughput 1536-well Notch1 Gamma-Secretase AlphaLISA Assay ENSG00000197971 ENSG00000137845 PMC8279913__F2 Current therapeutics against HCV ENSG00000088888 ENSG00000175104 ENSG00000164342 PMC9019414__F4 Network Pharmacology Approach for Uncovering the Antitumor Effects and Potential Mechanisms of the Sijunzi Decoction for the Treatment of Gastric Cancer ENSG00000002330 ENSG00000138798 ENSG00000108960 ENSG00000113161 ENSG00000087085 ENSG00000007908 ENSG00000112715 ENSG00000073756 ENSG00000106546 ENSG00000104368 ENSG00000132170 ENSG00000177606 ENSG00000125538 ENSG00000146648 ENSG00000127948 PMC8396838__F5 Comparative Transcriptome Analysis Reveals bmo-miR-6497-3p Regulate Circadian Clock Genes during the Embryonic Diapause Induction Process in Bivoltine Silkworm ENSG00000137992 PMC6590462__F6 Japanese encephalitis virus (JEV) intracellular effect mechanism ENSG00000100219 ENSG00000130669 PMC7880553__F2 Figure 2.Metabolites in early adulthood are associated with the cardiovascular phenome and identify pathways central to CVD development ENSG00000173599 ENSG00000062485 PMC4373423__F10 Suggested model for RF effects and interactions in various mouse tissues ENSG00000096717 PMC1195968__F1 RSV binding and triggering of cellular responses ENSG00000172936 ENSG00000136869 PMC6874141__F1 Ras signaling pathways ENSG00000146648 PMC9112062__F7 Endothelial AMPKA1/PRKAA1 exacerbates inflammation in HFD‐fed mice ENSG00000131473 ENSG00000132356 PMC11825097__F8 LIPG regulates goat intramuscular preadipocyte lipid deposition through the PPARA signaling pathway ENSG00000101670 ENSG00000042832 ENSG00000169710 PMC7094317__F2 Cell polarity pathways are targeted by diverse human viruses.Interplay between the Scribble (SCRIB), PAR, and Crumbs (CRB) complexes is central to the control of cell polarity ENSG00000070831 ENSG00000134982 ENSG00000130656 ENSG00000132849 PMC7763974__F4 Apoptosis induced by high levels of NO is mediated via activation of the extrinsic apoptosis pathway which involves the TNFR and Fas/Death Receptors ENSG00000102871 ENSG00000168040 ENSG00000175104 ENSG00000127191 ENSG00000026103 PMC2774076__F7 Current working model of the signaling pathway components (shaded areas) that are differentially regulated in C57 and CD-1 pup brain tissues and cultured NSCs under normoxic and hypoxic (Hx) conditions ENSG00000198793 ENSG00000168610 ENSG00000121966 PMC9230939__F2 Dual Roles of Protein-Bound Solutes as Toxins and Signaling Molecules in Uremia ENSG00000146648 ENSG00000106546 PMC6485344__F1 The Krebs cycle ENSG00000100412 ENSG00000105953 ENSG00000062485 PMC5066299__F35 S-propargyl-cysteine attenuates inflammatory response in rheumatoid arthritis by modulating the Nrf2-ARE signaling pathway ENSG00000125538 ENSG00000100985 ENSG00000079999 PMC6020056__F1 Complement cascades ENSG00000166278 PMC3269021__F8 Interaction of TOR pathway members for the regulation of phagocytosis ENSG00000005882 PMC4362528__F8 Human splicing code reveals new insights into the genetic determinants of disease ENSG00000100519 ENSG00000108298 ENSG00000160299 ENSG00000110107 ENSG00000092847 ENSG00000011376 ENSG00000074276 ENSG00000173546 ENSG00000165795 ENSG00000093009 ENSG00000010322 ENSG00000103723 ENSG00000187908 ENSG00000126001 ENSG00000135519 ENSG00000175390 ENSG00000197467 ENSG00000011485 ENSG00000165695 ENSG00000134909 PMC3143377__F2 Molecular Targeted Approaches in Mantle Cell lymphoma ENSG00000002330 PMC6042708__F14 Radio-sensitizing effects of VE-821 and beyond: Distinct phosphoproteomic and metabolomic changes after ATR inhibition in irradiated MOLT-4 cells ENSG00000131828 PMC9488512__F3 Chaotic activation of developmental signalling pathways drives idiopathic pulmonary fibrosis ENSG00000070193 ENSG00000164690 ENSG00000102678 PMC3143377__F3 Molecular Targeted Approaches in Mantle Cell lymphoma ENSG00000095585 ENSG00000198793 ENSG00000010671 PMC3195192__F2 VEGF-VEGFR signaling in lymphangiogenesis ENSG00000165197 ENSG00000112715 ENSG00000150630 PMC4151823__F9 WWOX At The Crossroads Of Cancer, Metabolic Syndrome Related Traits And CNS Pathologies ENSG00000198742 PMC8249521__F3 Introducing the novel Cytoscape app TimeNexus to analyze time-series data using temporal MultiLayer Networks (tMLNs) ENSG00000276618 ENSG00000100473 ENSG00000014138 ENSG00000177084 ENSG00000117399 ENSG00000274473 PMC5352450__F2 Next generation sequencing and its applications in HPVassociated cancers ENSG00000110330 ENSG00000116044 ENSG00000168036 ENSG00000111321 ENSG00000273686 ENSG00000168040 ENSG00000079999 ENSG00000224320 ENSG00000136997 ENSG00000131323 ENSG00000105810 ENSG00000077782 ENSG00000064012 ENSG00000139687 ENSG00000146648 PMC7063521__F1 Positive and negative regulators of hepcidin synthesis ENSG00000010704 ENSG00000106327 ENSG00000187045 ENSG00000178752 ENSG00000168610 PMC4811695__F1 Recent Advances in Adipose mTOR Signaling and Function: Therapeutic Prospects ENSG00000101407 ENSG00000148400 ENSG00000074181 ENSG00000106070 ENSG00000198793 ENSG00000155792 ENSG00000167965 PMC6927459__F12 The impact of PSC and tumor cells on immune cells in the pancreatic cancer stroma ENSG00000102962 ENSG00000107562 ENSG00000275385 ENSG00000163599 ENSG00000198793 ENSG00000113140 ENSG00000171791 ENSG00000231179 ENSG00000137845 ENSG00000168610 ENSG00000239732 ENSG00000111537 ENSG00000133110 ENSG00000181847 ENSG00000163235 ENSG00000132646 ENSG00000113520 ENSG00000204520 ENSG00000135919 PMC8648391__F1 Potential synthetic lethal strategy with PARP inhibitors: perspective on ‘Inactivation of the tumor suppressor p53 by long noncoding RNA RMRP’ ENSG00000131876 PMC2757632__F1 O-GlcNAc cycling: Implications for Neurodegenerative disorders ENSG00000147162 ENSG00000198408 ENSG00000182606 ENSG00000213024 PMC533963__F11 Model illustrating the signaling pathway through which Brk participates in EGF-induced cell migration and invasion ENSG00000138798 ENSG00000099942 ENSG00000146648 PMC6591840__F5 Potential mechanisms underlying EOC chemoresistance and the sensitizing effect of PI3K inhibition ENSG00000170558 ENSG00000198793 ENSG00000062485 PMC4811695__F3 Recent Advances in Adipose mTOR Signaling and Function: Therapeutic Prospects ENSG00000101407 ENSG00000039537 ENSG00000176692 ENSG00000105550 ENSG00000198793 ENSG00000155792 ENSG00000164327 PMC6927459__F10 The crosstalk between PSC and pancreatic cancer cells ENSG00000197043 ENSG00000135218 ENSG00000105329 ENSG00000138798 ENSG00000026508 ENSG00000115419 ENSG00000140443 ENSG00000135919 ENSG00000137801 PMC9466598__F1 The hedgehog signaling pathway in rheumatic diseases: An overview ENSG00000092439 ENSG00000197594 ENSG00000128602 PMC7232513__F2 Interplay between virus-induced cellular aggregates and inclusions ENSG00000128272 ENSG00000144895 ENSG00000102034 ENSG00000123908 PMC9634253__F2 Hypoxia-inducible factor 1-alpha is a driving mechanism linking chronic obstructive pulmonary disease to lung cancer ENSG00000149311 ENSG00000198793 ENSG00000173846 ENSG00000168610 PMC6223216__F1 Wnt signalling pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000163914 PMC7383044__F1 Activated c-Mpl dimer leads to activation of multiple signaling pathways which promote proliferation and platelet production ENSG00000117400 PMC6234444__F1 Induction of oxidative stress by a virus infection and genome replication ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC2784899__F7 Model to account for responsiveness to cAMP level in activation but not inactivation of eumelanin synthesis ENSG00000102858 ENSG00000101440 ENSG00000198125 PMC11669278__F7 Interaction network among the key genes, enzymes, pathways, and metabolites ENSG00000125166 ENSG00000114200 ENSG00000124608 ENSG00000110721 ENSG00000113492 ENSG00000100288 ENSG00000172890 ENSG00000070669 ENSG00000173868 ENSG00000129219 ENSG00000198380 ENSG00000129167 ENSG00000172482 ENSG00000131480 ENSG00000166123 ENSG00000149313 ENSG00000084774 ENSG00000167701 PMC9259182__F6 Identification of molecular mechanisms underlying the therapeutic effects of Xintong granule in coronary artery disease by a network pharmacology and molecular docking approach ENSG00000007908 ENSG00000162692 ENSG00000164305 PMC5746547__F1 PFKFB3-driven glycolysis and the central role of FAO via CPT1a function in ECs (a) Schematic of PFKFB3 as a key regulator of the glycolytic activity in ECs and the angiogenic switch ENSG00000180210 ENSG00000117707 PMC8588021__F3 Neuroprotective Potential of Chrysin: Mechanistic Insights and Therapeutic Potential for Neurological Disorders ENSG00000181019 ENSG00000125538 ENSG00000079999 PMC5833380__F3 ROS-independent ER stress-mediated NRF2 activation promotes warburg effect to maintain stemness-associated properties of cancer-initiating cells ENSG00000180210 ENSG00000074800 ENSG00000023909 ENSG00000115419 ENSG00000159399 PMC4917857__F3 Cytochrome P450 metabolism of the post-lanosterol intermediates explains enigmas of cholesterol synthesis ENSG00000132196 ENSG00000116133 ENSG00000172893 ENSG00000149809 ENSG00000109929 ENSG00000113161 ENSG00000104549 PMC2820725__F4 Redox signaling responses in DCs and T cells during T cell activation ENSG00000213658 PMC4917857__F7 Cytochrome P450 metabolism of the post-lanosterol intermediates explains enigmas of cholesterol synthesis ENSG00000132196 ENSG00000167910 ENSG00000036530 ENSG00000135929 PMC4336945__F3 Roles of Microphthalmia Transcription Factor and pigmentation in melanoma ENSG00000115138 ENSG00000080166 ENSG00000107165 PMC3558493__F8 ErbB2-Dependent Chemotaxis Requires Microtubule Capture and Stabilization Coordinated by Distinct Signaling Pathways ENSG00000070831 ENSG00000134982 ENSG00000149269 PMC2888582__F6 Proteomics-Based Systems Biology Modeling of Bovine Germinal Vesicle Stage Oocyte and Cumulus Cell Interaction ENSG00000100522 ENSG00000142798 ENSG00000173218 ENSG00000072274 ENSG00000168036 ENSG00000010278 ENSG00000174021 ENSG00000119608 ENSG00000130402 ENSG00000185825 ENSG00000291368 ENSG00000115091 ENSG00000163956 ENSG00000142627 ENSG00000143549 ENSG00000197081 ENSG00000078369 ENSG00000078668 ENSG00000164171 ENSG00000108839 ENSG00000164404 ENSG00000133110 ENSG00000080371 ENSG00000100941 ENSG00000162692 ENSG00000146648 ENSG00000101608 PMC9257096__F15 KIFC3 Promotes Proliferation, Migration, and Invasion in Colorectal Cancer via PI3K/AKT/mTOR Signaling Pathway ENSG00000170558 ENSG00000198793 ENSG00000123374 ENSG00000140859 PMC5520463__F1 The serine synthesis pathway (SSP) diverges from glycolysis utilising the intermediate 3P-glycerate, which is converted by PHGDH, PSAT-1, and PSPH into serine and then glycine ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC6168630__F1 PI3KD activation in B- and T-cells during class-switch recombination ENSG00000095585 ENSG00000291603 ENSG00000213658 ENSG00000186716 ENSG00000175097 PMC9562258__F1 BRAF Inhibitors in Non-Small Cell Lung Cancer ENSG00000157764 PMC8139249__F1 Bone Cells Differentiation: How CFTR Mutations May Rule the Game of Stem Cells Commitment? ENSG00000170365 ENSG00000120149 ENSG00000105996 PMC2875624__F1 Alterations in transforming growth factor beta signaling cause changes in chondrocyte differentiation and osteoarthritis development ENSG00000170365 ENSG00000137834 ENSG00000198742 PMC4552299__F2 Transcriptomic Analysis and Meta-Analysis of Human Granulosa and Cumulus Cells ENSG00000172794 ENSG00000122122 ENSG00000278550 ENSG00000235568 ENSG00000162745 ENSG00000077984 ENSG00000103569 ENSG00000091592 ENSG00000091106 ENSG00000117091 ENSG00000127954 ENSG00000163421 ENSG00000115523 PMC4479532__F3 Activation of a B-cell and its regulation by miR-155 ENSG00000186716 PMC4190552__F1 Roles of leukotrienes and acetylation in the expression of pro-inflammatory mediators through the NFKB pathway ENSG00000104856 ENSG00000226275 PMC2891887__F2 Lymphangiogenesis and Lymphatic Metastasis in Breast Cancer ENSG00000137077 ENSG00000126353 ENSG00000112715 ENSG00000121966 ENSG00000150630 PMC4702319__F1 CagA mediates dysregulation of the Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000134982 ENSG00000168036 ENSG00000167074 PMC3526371__F1 NFKB activation in pathogenesis and therapy of cancer ENSG00000173039 ENSG00000172936 ENSG00000175104 ENSG00000127191 ENSG00000146648 PMC3674567__F4 Postulated model for regulation of large luteal cells of ruminants (left) and primates (right) ENSG00000073756 PMC9398379__F2 Whiff of the future: functions of phenylalanine‐derived aroma compounds and advances in their industrial production ENSG00000084774 PMC7950231__F5 Induction of type I interferons and signalling leading to the innate immune response during SARS-CoV-2 infection and drug pair action site ENSG00000104365 ENSG00000213928 ENSG00000100906 ENSG00000089127 ENSG00000109320 ENSG00000188056 ENSG00000269335 ENSG00000213341 ENSG00000135341 ENSG00000142166 ENSG00000183735 ENSG00000105397 ENSG00000115415 ENSG00000263528 ENSG00000172936 ENSG00000131323 ENSG00000111331 ENSG00000175104 PMC3720155__F2 Sketch of the relationship between IGF signalling, the PI3K pathway and androgen responses in the prostate ENSG00000109452 PMC8282456__F3 Recent Advances in Heterologous Synthesis Paving Way for Future Green-Modular Bioindustries: A Review With Special Reference to Isoflavonoids ENSG00000087245 ENSG00000138823 ENSG00000171791 ENSG00000100985 PMC7563527__F1 Versatile cross-talks of CAF with activated progenitor cells and HCC ENSG00000019991 ENSG00000108691 ENSG00000105329 ENSG00000164690 PMC4522610__F1 Main extracellular stimuli and intracellular signaling pathways leading to astrocyte reactivity in ND ENSG00000242689 ENSG00000125538 ENSG00000131095 ENSG00000168610 PMC10266770__F1 STAT2 deficiency and other inborn and acquired defects of type I IFN signaling result in susceptibility to viral infections ENSG00000105397 ENSG00000115415 PMC2944809__F5 Inhibition of TIR Domain Signaling by TcpC: MyD88-Dependent and Independent Effects on Escherichia coli Virulence ENSG00000183735 ENSG00000175899 ENSG00000136869 ENSG00000127191 ENSG00000168610 PMC4310697__F4 Toll-like receptor (TLR), nucleotide-binding oligomerization domain (NOD)-like receptor (NLR), and retinoic acid-inducible gene (RIG-I)-like receptor (RLR) signaling ENSG00000187796 ENSG00000172936 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC4173780__F1 Strategies for the production of linear, primary alcohols ENSG00000168040 ENSG00000132693 ENSG00000106546 PMC8490190__F2 Emerging Nondopaminergic Medications for Parkinson’s Disease: Focusing on A2A Receptor Antagonists and GLP1 Receptor Agonists ENSG00000150907 ENSG00000198793 PMC5497827__F1 Summary of the canonical Th2 pathway and “new spins” on the pathways that lead to allergic inflammation ENSG00000103266 ENSG00000137033 ENSG00000213047 ENSG00000113520 ENSG00000145777 ENSG00000131724 ENSG00000166090 ENSG00000106546 PMC4057583__F10 Link between NFKBIA and EGFR pathway in Glioblastoma ENSG00000100906 ENSG00000138798 ENSG00000146648 PMC7992789__F3 Roles of miRNAs in modulating the autophagy process in human breast cancer ENSG00000152348 ENSG00000188554 ENSG00000144848 ENSG00000005893 ENSG00000284099 ENSG00000145782 ENSG00000140464 ENSG00000057663 PMC8267830__F1 Feedback, Crosstalk and Competition: Ingredients for Emergent Non-Linear Behaviour in the PI3K/mTOR Signalling Network ENSG00000106070 ENSG00000155792 PMC6367540__F4 Figure illustrates the signal transduction cascades of TGF/BMP, Wnt, Hedgehog signaling pathway in the development of cranial sutures ENSG00000170365 ENSG00000106571 ENSG00000166813 ENSG00000168036 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC5869864__F3 mTORC1 as the main gateway to autophagy ENSG00000177169 ENSG00000110497 ENSG00000123395 ENSG00000112561 PMC4643669__F1 Novel role of miR-33 in regulating of mitochondrial function ENSG00000138029 ENSG00000160179 ENSG00000148339 ENSG00000106459 ENSG00000005469 PMC5739091__F1 Rag GTPase-dependent amino acid signaling pathway upstream of mTORC1 ENSG00000177058 ENSG00000274070 ENSG00000239282 PMC3392447__F2 Routes of AMPAR trafficking ENSG00000100151 ENSG00000130294 ENSG00000155974 PMC3081173__F4 Cell adhesion molecules nectins and associating proteins: Implications for physiology and pathology ENSG00000136158 ENSG00000070831 PMC8467578__F1 Looking at Alzheimer’s Disease Pathogenesis from the Nuclear Side ENSG00000142192 ENSG00000096717 ENSG00000137845 PMC5223230__F1 A central role of Batf3 DCs and the STING pathway in orchestrating anti-tumor T cell responses ENSG00000123685 ENSG00000169245 ENSG00000138755 ENSG00000277943 PMC4074565__F1 Regulation of mTORC1 by amino acids ENSG00000159224 ENSG00000114388 ENSG00000085415 ENSG00000149357 ENSG00000217128 ENSG00000127580 ENSG00000164654 PMC9340325__F2 Cell secretomes for wound healing and tissue regeneration: Next generation acellular based tissue engineered products ENSG00000162711 ENSG00000125538 PMC7767850__F4 Immune escape through PD-1/PD-L1 pathway in B-cell malignancies ENSG00000111537 ENSG00000134982 ENSG00000273686 PMC6114981__F7 FABP5-mediated transcriptional controlling network of mitochondrial functions in PCa cells ENSG00000100412 ENSG00000116688 PMC7767850__F3 PD-1/PD-L1/PD-L2 pathway hijacking in oncology ENSG00000111537 PMC4364059__F2 TLR and NLR pathways ENSG00000167207 ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000106100 ENSG00000184216 PMC7053056__F1 Kynurenine pathway represents one of three routes for NAD+ production or recycling ENSG00000105835 ENSG00000172890 ENSG00000152620 ENSG00000278488 ENSG00000077463 ENSG00000142082 ENSG00000178685 ENSG00000077009 ENSG00000157064 ENSG00000124523 ENSG00000173614 ENSG00000089163 ENSG00000125166 ENSG00000187531 ENSG00000162882 ENSG00000138617 ENSG00000183077 ENSG00000111339 ENSG00000173200 ENSG00000188676 ENSG00000137817 ENSG00000283100 ENSG00000151883 ENSG00000156219 ENSG00000167311 ENSG00000102699 ENSG00000059378 ENSG00000041880 ENSG00000008130 ENSG00000096717 ENSG00000106733 ENSG00000227345 ENSG00000111224 PMC8267830__F2 Feedback, Crosstalk and Competition: Ingredients for Emergent Non-Linear Behaviour in the PI3K/mTOR Signalling Network ENSG00000106070 ENSG00000155792 ENSG00000164327 PMC4364059__F3 The inflammasome pathway ENSG00000162711 ENSG00000091106 ENSG00000105483 PMC3817019__F1 How the VEGF-A signaling pathway is linked to its main biological functions.Notes: VEGF-A can bind VEGFR-2 dimer ENSG00000112715 ENSG00000124181 ENSG00000118257 PMC3817019__F2 EGFR pathway and its main downstream effectors, PI3K/AKT and KRAS/BRAF/MEK/MERK.Notes: Activated AKT and MEK/MERK can induce cancer cell proliferation and invasion ENSG00000157764 ENSG00000146648 PMC4831838__F4 Proteomic Characterization of Middle Ear Fluid Confirms Neutrophil Extracellular Traps as a Predominant Innate Immune Response in Chronic Otitis Media ENSG00000277571 ENSG00000169896 ENSG00000278624 ENSG00000100448 ENSG00000198183 ENSG00000163220 ENSG00000277804 ENSG00000187908 ENSG00000005381 ENSG00000293532 ENSG00000101425 ENSG00000162896 PMC7962349__F6 Intervention of natural products from traditional Chinese medicine on the TME ENSG00000136869 ENSG00000168610 PMC4380398__F7 Pik3ip1 Modulates Cardiac Hypertrophy by Inhibiting PI3K Pathway ENSG00000198793 ENSG00000284161 ENSG00000167658 ENSG00000100100 PMC5955471__F9 Lucidone suppresses dengue viral replication through the induction of heme oxygenase-1 ENSG00000156273 ENSG00000079999 PMC4926194__F2 Known host targets of phleboviral NSs proteins in retinoic acid-inducible gene 1 (RIG-I) signaling and type I IFN induction ENSG00000183735 ENSG00000088888 ENSG00000121060 PMC6844227__F14 KEGG pathway annotations of the PI3K-Akt pathway in non-small cell lung cancer ENSG00000177455 ENSG00000103479 ENSG00000033327 ENSG00000002330 ENSG00000105401 ENSG00000186716 ENSG00000198793 ENSG00000169047 ENSG00000167182 PMC9301867__F5 Whole-exome sequencing identified mutational profiles of urothelial carcinoma post kidney transplantation ENSG00000087245 ENSG00000150907 ENSG00000198793 ENSG00000169429 ENSG00000169032 ENSG00000112715 ENSG00000121879 ENSG00000146648 ENSG00000169375 ENSG00000139687 ENSG00000124762 ENSG00000108840 PMC4695847__F1 Functions of mono-ADP-ribosylating ARTD (ADP-ribosyltransferase diphtheria toxin-like) enzymes and of mono-ADP-ribosylating Sirtuins in signaling ENSG00000113520 ENSG00000198846 ENSG00000077463 ENSG00000089163 ENSG00000106546 PMC5593680__F1A Targeting metabolism and AMP-activated kinase with metformin to sensitize non-small cell lung cancer (NSCLC) to cytotoxic therapy: translational biology and rationale for current clinical trials ENSG00000131473 ENSG00000198793 ENSG00000146648 ENSG00000026103 PMC7039855__F1 Wnt signaling pathways ENSG00000169071 ENSG00000134982 ENSG00000177606 ENSG00000185483 ENSG00000173273 PMC7039855__F2 Wnt/Beta-catenin signaling in DCs and tumors in driving immune suppression and immune evasion ENSG00000281324 ENSG00000162337 ENSG00000125538 ENSG00000198793 ENSG00000168036 ENSG00000173578 ENSG00000126353 ENSG00000049768 ENSG00000277943 ENSG00000196628 ENSG00000143184 PMC3835153__F2 Cisplatin resistance.Notes: Cisplatin creates DNA adducts and activates the apoptotic pathway, thus killing rapidly dividing cells ENSG00000123191 ENSG00000164305 PMC6386927__F6 THD on a crosstalk in Fzd/GSK3B/Beta-catenin/P62 axis ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC11747375__F3 GA inhibited the proliferation and migration of VSMCs ENSG00000070831 ENSG00000171435 ENSG00000026103 PMC11747375__F1 Molecular targets and mechanism of action of GA in hyperlipidemia ENSG00000135218 ENSG00000002330 ENSG00000096088 ENSG00000007171 ENSG00000026103 PMC11747375__F2 Inhibition of atherosclerotic lesions by GA ENSG00000070831 ENSG00000004142 ENSG00000171435 ENSG00000086991 PMC3327724__F1 Heroin metabolic pathway in humans ENSG00000171234 ENSG00000087085 PMC8822594__F3 New insights into the interplay between long non‐coding RNAs and RNA‐binding proteins in cancer ENSG00000058085 ENSG00000127528 ENSG00000139842 ENSG00000172936 ENSG00000168610 PMC6244246__F5 Integrated transcriptomics and metabolomics pathway diagrams ENSG00000087253 ENSG00000065357 ENSG00000100288 ENSG00000137392 ENSG00000198670 ENSG00000116906 PMC5555522__F3 Molecular Pathway in Thyroid Cancer ENSG00000157764 ENSG00000198793 ENSG00000165409 PMC7571161__F4 IFN signaling and synthesis pathway ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000130234 ENSG00000107201 ENSG00000164342 PMC3822617__F3 Multifunctionality of ARC in regulating apoptosis signalling ENSG00000002330 ENSG00000198576 ENSG00000168040 ENSG00000026103 PMC7140698__F9 Effects of Dot1L inhibition in influenza virus infected cells ENSG00000183735 ENSG00000088888 ENSG00000104885 ENSG00000121060 PMC8125073__F5 Oral Epithelial Cells Distinguish between Candida Species with High or Low Pathogenic Potential through MicroRNA Regulation ENSG00000145362 ENSG00000084676 ENSG00000100387 ENSG00000163235 ENSG00000170214 ENSG00000148926 ENSG00000198793 ENSG00000004487 ENSG00000154582 ENSG00000049768 ENSG00000187840 ENSG00000007171 PMC4327623__F2 The main signaling pathways involved in the neuroprotective action of GDNF on dopaminergic neurons ENSG00000171791 ENSG00000164305 PMC8125073__F7 Oral Epithelial Cells Distinguish between Candida Species with High or Low Pathogenic Potential through MicroRNA Regulation ENSG00000172005 ENSG00000117298 ENSG00000143839 ENSG00000142224 ENSG00000135517 PMC4926123__F7 Anti-tumor effect of Beta-glucan from Lentinus edodes and the underlying mechanism ENSG00000143799 ENSG00000132906 ENSG00000168610 PMC4988449__F1 Schematic model depicting how ERK1/2 activity is transduced through the Shoc2 scaffold ENSG00000112851 ENSG00000168938 ENSG00000108061 PMC8306148__F1 Identification and Characterization of Multiple Myeloma Stem Cell-Like Cells ENSG00000171016 ENSG00000106571 ENSG00000134982 ENSG00000166813 ENSG00000198793 ENSG00000154309 ENSG00000164690 ENSG00000128602 PMC8917804__F3 Cellular and humoral host immune responses to SARS-CoV-2 viral infection ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000130234 ENSG00000172936 ENSG00000276561 ENSG00000164342 ENSG00000062485 PMC4613517__F1 Value of monitoring Nrf2 activity for the detection of chemical and oxidative stress ENSG00000178573 ENSG00000100387 ENSG00000079999 PMC11195429__F2 CGAS-STING signaling pathway ENSG00000143799 ENSG00000112343 ENSG00000169914 ENSG00000118369 ENSG00000163904 ENSG00000164430 ENSG00000204160 ENSG00000197594 ENSG00000135912 ENSG00000138468 ENSG00000170703 ENSG00000163687 ENSG00000172977 PMC11195429__F3 Antitumor therapies awake the cGAS-STING signaling to accelerate the antitumor immunity ENSG00000132906 ENSG00000169245 ENSG00000164430 ENSG00000173638 ENSG00000138755 PMC10308384__F5 Therapeutic strategies to recover ependymal barrier after inflammatory damage: relevance for recovering neurogenesis during development ENSG00000214285 ENSG00000196352 ENSG00000136869 ENSG00000171885 PMC5929409__F4A In vitro study on role of σB protein in avian reovirus pathogenesis ENSG00000182718 ENSG00000154342 ENSG00000137834 ENSG00000143546 ENSG00000163220 ENSG00000089041 ENSG00000168040 ENSG00000007171 ENSG00000163435 ENSG00000162733 ENSG00000171720 ENSG00000125398 ENSG00000156427 ENSG00000291837 ENSG00000136869 ENSG00000100985 ENSG00000204217 PMC9578963__F1 Orchestrated signaling by PI3KA and PTEN at the membrane interface ENSG00000124102 ENSG00000002330 ENSG00000143376 ENSG00000047849 PMC10308384__F9 Therapeutic strategies to recover ependymal barrier after inflammatory damage: relevance for recovering neurogenesis during development ENSG00000129654 ENSG00000136869 PMC5666046__F3 Prolonged mechanical loading beyond physiological levels on tenocytes, increases the expression of IL-1B and CCL2 ENSG00000108691 ENSG00000125538 ENSG00000026103 PMC9396386__F6 Time-course transcriptome analyses of spleen in rainbow trout (Oncorhynchus mykiss) post-Flavobacterium psychrophilum infection ENSG00000169248 ENSG00000169245 ENSG00000154589 ENSG00000100906 ENSG00000170458 ENSG00000109320 ENSG00000136997 ENSG00000172936 ENSG00000213341 ENSG00000154016 ENSG00000113302 PMC7610305__F1 Upregulated AspH activates the Notch signaling pathway ENSG00000112576 ENSG00000168214 ENSG00000119888 ENSG00000132646 ENSG00000026508 ENSG00000198363 PMC406426__F1 What is the role of mTLR7 in the antiviral response? Many ssRNA viruses (including VSV and influenza viruses) engage host cell receptors that trigger endocytosis ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000175104 ENSG00000164342 PMC5677537__F1 Ethanol upregulates TNFA in Kupffle cells via the activation of multiple pathways Ethanol administration activates the TLR4 pathway, ROS production and complement activation to increase the expression of TNFA ENSG00000183735 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC4983472__F5 Intracellular and intercellular signaling and cellular dynamics in bone healing and bone remodeling ENSG00000178860 ENSG00000152266 ENSG00000170365 ENSG00000168036 PMC8446672__F1 Targeting the Interleukin-23/Interleukin-17 Inflammatory Pathway: Successes and Failures in the Treatment of Axial Spondyloarthritis ENSG00000162594 ENSG00000105397 ENSG00000137265 ENSG00000168610 PMC5666046__F2 Effect of mechanical strain on tenocyte ENSG00000108691 ENSG00000125538 ENSG00000173599 ENSG00000121807 PMC3205681__F2 Post-translational modifications (PTMs) of transcription factors ENSG00000147162 ENSG00000075142 ENSG00000198408 ENSG00000182759 PMC3993104__F2 Interplay between host and bacterial factors leads to tissue destruction, vascular leakage, and hyperinflammation in invasive GAS disease ENSG00000134982 ENSG00000122194 ENSG00000281857 PMC1327675__F3 Interactive map (pathway) of 46 genes/proteins created in PathwayAssist® from the list of transcripts up-regulated in the testes of ABP-transgenic mice ENSG00000051523 ENSG00000261832 ENSG00000111049 ENSG00000124107 ENSG00000197616 ENSG00000162772 ENSG00000010671 ENSG00000157557 ENSG00000185652 ENSG00000082175 ENSG00000196549 ENSG00000129214 ENSG00000136997 ENSG00000175899 ENSG00000026508 ENSG00000066136 ENSG00000001626 ENSG00000167755 ENSG00000084774 PMC6034133__F8 Inflammation leads through PGE/EP 3 signaling to HDAC5/MEF2‐dependent transcription in cardiac myocytes ENSG00000156299 ENSG00000108840 PMC5017163__F1 Different strategies of metabolic regulation in cyanobacteria: from transcriptional to biochemical control ENSG00000261701 ENSG00000115271 PMC6406345__F3 Protein–protein interaction network of associated genes in the etiopathogenesis of ANCA-associated vasculitis ENSG00000230930 ENSG00000239732 ENSG00000179344 ENSG00000277804 ENSG00000277263 ENSG00000204520 ENSG00000150637 PMC6739476__F7 Pathway map assigned for MAPKs signalling ENSG00000144063 ENSG00000180667 ENSG00000149489 ENSG00000172005 ENSG00000272398 ENSG00000135517 ENSG00000149418 PMC11195429__F1 cGAS-STING and cell death pathways ENSG00000278718 ENSG00000132906 ENSG00000162711 ENSG00000124256 ENSG00000183735 ENSG00000164430 ENSG00000168404 ENSG00000164305 ENSG00000285379 PMC11682996__F1 Mechanisms of IFI44L in human diseases ENSG00000183735 ENSG00000285379 ENSG00000142166 PMC5381938__F1 Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy ENSG00000111537 ENSG00000134982 ENSG00000163599 PMC9314331__F5 S6K functions in feedback regulation ENSG00000169047 PMC6755182__F8 Ginsenoside Rb1 prevent the steroid-induced avascular necrosis of the femoral head through BMP-2 and VEGF signaling pathway ENSG00000139687 PMC9522762__F2 Liver kinase B1 in tumor progression through regulation of lipid metabolism ENSG00000131473 ENSG00000135218 ENSG00000160584 ENSG00000198793 ENSG00000170145 ENSG00000169710 ENSG00000160741 ENSG00000135250 PMC3708584__F3 ‘ErbB signalling' and ‘TGFB pathway' in the canonical pathway ENSG00000133937 ENSG00000113070 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000156574 ENSG00000164093 ENSG00000169752 ENSG00000178568 PMC4351296__F6 Mechanism of dynamics of the EGFR-NHERF1-NHE1 signaling axis and its role in PDAC growth and invasion.In control cells EGFR, NHERF1, and NHE1 are separate ENSG00000138798 ENSG00000109062 ENSG00000146648 PMC3212439__F5 Immunoproteasomes Regulate Lps-Induced Trif/Tram Signaling Pathway in Murine Macrophages ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 PMC4624194__F1 STAT3 Signaling in Polycystic Kidney Disease ENSG00000019991 ENSG00000291971 ENSG00000138798 ENSG00000168610 PMC8418613__F4 STRING pathway analysis of LM and LuM CD11b+ druggable proteomic targets ENSG00000008438 ENSG00000123416 ENSG00000142798 ENSG00000198053 ENSG00000130702 ENSG00000188229 ENSG00000150093 ENSG00000137845 ENSG00000168961 ENSG00000196396 ENSG00000116962 ENSG00000172037 ENSG00000277571 ENSG00000068976 ENSG00000108679 ENSG00000005893 ENSG00000189403 ENSG00000100504 ENSG00000275565 ENSG00000155657 ENSG00000161905 ENSG00000103035 ENSG00000070961 ENSG00000163902 ENSG00000008394 ENSG00000197616 ENSG00000168610 ENSG00000164163 ENSG00000155660 ENSG00000143162 ENSG00000072110 ENSG00000100985 ENSG00000005381 ENSG00000184897 ENSG00000104325 PMC6269503__F1 Role of Hippo signaling in regulating immunity ENSG00000164430 ENSG00000163739 ENSG00000172936 ENSG00000131023 PMC3946526__F6 The Expression and Prognostic Significance of Retinoic Acid Metabolising Enzymes in Colorectal Cancer ENSG00000095596 ENSG00000121207 ENSG00000003137 PMC8026967__F3 Beyond DNA repair and chromosome instability—Fanconi anaemia as a cellular senescence-associated syndrome ENSG00000083093 ENSG00000188827 ENSG00000181544 ENSG00000187790 ENSG00000168411 ENSG00000115392 ENSG00000187741 ENSG00000112039 ENSG00000158169 ENSG00000131944 ENSG00000144554 ENSG00000108384 ENSG00000051180 PMC5911217__F7 BRD7 regulates the insulin signaling pathway by increasing phosphorylation of GSK3B ENSG00000124733 ENSG00000198793 ENSG00000166164 PMC6600376__F2 Mitogen-activated protein kinase (MAPK) cascades in activated, myofibroblast-like hepatic stellate cells (HSC/MFs) ENSG00000070831 ENSG00000138798 ENSG00000163914 ENSG00000177606 ENSG00000075891 ENSG00000084774 PMC6600376__F3 Major phenotypic responses in activated, myofibroblast-like cells (HSC/MFs) as well as, more generally, in hepatic MFs ENSG00000105329 PMC11076734__F4 PINs-mediated auxin transport regulation during salt stress ENSG00000127445 ENSG00000100485 ENSG00000102309 PMC6600376__F1 ERK Pathway in Activated, Myofibroblast-Like, Hepatic Stellate Cells: A Critical Signaling Crossroad Sustaining Liver Fibrosis ENSG00000019991 ENSG00000262406 ENSG00000111537 ENSG00000105329 ENSG00000163235 ENSG00000100985 ENSG00000121966 PMC3638125__F2 Intracellular signaling pathways of GLP-1R in the pancreatic Beta-cell ENSG00000128272 ENSG00000150907 ENSG00000146648 PMC3172156__F2 RLR signaling pathway showing RIG-I bound to ligand RNA and signaling downstream to IRF-3 and NF-kB to induce IFNA/B production from a virus-infected cell ENSG00000131323 PMC8908406__F1 Dawn of precision medicine in diffuse-type gastric cancer ENSG00000019991 ENSG00000066468 ENSG00000144410 ENSG00000198793 PMC6121065__F1 mBDNF/TrkB and proBDNF/p75NTRsignaling pathways regulate gamma-aminobutyric acid neurotransmission ENSG00000169291 PMC11089157__F4 Post-translational regulation of FOXK2 ENSG00000149311 ENSG00000198793 ENSG00000141568 ENSG00000096717 ENSG00000084774 PMC11089157__F5 Emerging roles of FOXK2 in cancers and metabolic disorders ENSG00000084093 ENSG00000163930 ENSG00000134086 ENSG00000141568 ENSG00000265972 ENSG00000169375 PMC4335356__F4 Spatio-temporal 16p11.2 protein network implicates cortical late mid-fetal brain development and KCTD13-Cul3-RhoA pathway in psychiatric diseases ENSG00000280789 ENSG00000142192 ENSG00000149930 ENSG00000167371 ENSG00000101266 ENSG00000149929 ENSG00000102879 ENSG00000150991 ENSG00000132646 ENSG00000177606 ENSG00000090238 ENSG00000169592 ENSG00000149927 PMC11089157__F3 Transcriptional regulation of FOXK2 ENSG00000125398 ENSG00000138798 ENSG00000141568 ENSG00000146648 PMC9513364__F3 Advances in surface modification of tantalum and porous tantalum for rapid osseointegration: A thematic review ENSG00000170365 ENSG00000291837 ENSG00000168036 ENSG00000204217 PMC2747343__F1 Ingenuity pathway analysis shows 17 genes from the 180 genes associated with the NF-E2-related factor-2 (NRF-2)-mediated oxidative stress response pathway ENSG00000128272 ENSG00000177606 ENSG00000152137 ENSG00000117707 ENSG00000135624 ENSG00000089159 ENSG00000138356 PMC11082402__F5 Riboflavin metabolic pathway ENSG00000160688 PMC9357610__F5 Pirfenidone alleviates cardiac fibrosis induced by pressure overload via inhibiting TGF‐B1/Smad3 signalling pathway PMC5291771__F1 The signaling pathway of DDX41 in innate immunity ENSG00000132109 ENSG00000183735 ENSG00000010671 PMC5528350__F1 miRNA deregulation in cancer ENSG00000136997 ENSG00000124571 ENSG00000128191 ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC7191850__F7 Graphical summary of MITF action as a potent antioxidant in RPE cells through regulating NRF2-dependant antioxidant signaling to protect the neural retina against oxidative stress-induced degeneration ENSG00000197713 ENSG00000178573 ENSG00000023909 PMC10148080__F4 NAT10 as ac4C writer in diseases ENSG00000276725 ENSG00000135446 ENSG00000123374 ENSG00000135372 PMC4131779__F2 Host genetic factors in American cutaneous leishmaniasis: a critical appraisal of studies conducted in an endemic area of Brazil ENSG00000151702 ENSG00000185591 ENSG00000168610 PMC6144938__F3 Important steps in cholesterol synthesis and homeostasis ENSG00000130164 ENSG00000116133 ENSG00000172893 ENSG00000160179 PMC3358533__F5 PPARA signaling canonical pathway in chronic arsenic-exposed lung epithelial cells ENSG00000105993 ENSG00000197386 ENSG00000131910 ENSG00000175104 ENSG00000127191 ENSG00000148719 PMC9284900__F8 METTL3 mediates Ang-II-induced cardiac hypertrophy through accelerating pri-miR-221/222 maturation in an m6A-dependent manner ENSG00000155011 ENSG00000168036 ENSG00000113360 ENSG00000165819 PMC4267524__F8 Endogenous Voltage Potentials and the Microenvironment: Bioelectric Signals that Reveal, Induce and Normalize Cancer ENSG00000148798 PMC7694477__F1 Hereditary hemorrhagic telangiectasia (HHT) and the transforming growth factor beta (TGFB) signaling pathway in endothelial cells ENSG00000170365 ENSG00000204217 ENSG00000125968 ENSG00000163217 PMC4197858__F2 Principles of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in disease ENSG00000197713 ENSG00000153574 ENSG00000116649 ENSG00000102172 PMC4197858__F3 Principles of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in disease ENSG00000228716 ENSG00000113161 ENSG00000120942 PMC7286357__F8 Proposed mechanism by which Xbp1s promotes inflammation and injury in renal tubular cells during AKI in sepsis ENSG00000170458 ENSG00000136869 ENSG00000100219 PMC3836044__F1 Canonical (Wnt/Beta-catenin) pathway ENSG00000134982 ENSG00000168036 ENSG00000165282 PMC4504424__F2 Cytokines determined to be up-regulated in plasma collected from pancreatic adenocarcinoma patients ENSG00000163220 ENSG00000113520 ENSG00000112715 ENSG00000112115 PMC12106287__F1 Membrane receptor tyrosine kinases-linked anti-BC effects of flavonoids as modulators of the MAPK signaling pathway, highlighting their capacity to function as sensitizers in chemoresistant BC and/or as chemopreventive agents ENSG00000070831 ENSG00000163914 PMC9476305__F5 Recent advances and limitations of mTOR inhibitors in the treatment of cancer ENSG00000169047 ENSG00000198793 ENSG00000140443 PMC6627216__F1 Synthetic lethality of PARP-inhibitors in HR-deficient tumors ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000183765 PMC9307349__F2 Active Compounds and Targets of Yuanzhi Powder in Treating Alzheimer's Disease and Its Relationship with Immune Infiltration Based on HPLC Fingerprint and Network Pharmacology ENSG00000145632 ENSG00000152661 ENSG00000108691 ENSG00000117525 ENSG00000100906 ENSG00000118785 ENSG00000113327 ENSG00000065559 ENSG00000171791 ENSG00000169032 ENSG00000139687 ENSG00000186297 PMC4555184__F3 Stem cell mechanobiology: diverse lessons from bone marrow ENSG00000160789 ENSG00000163914 PMC6359168__F3 Apoptosis induced by Endoplasmic Reticulum (ER) stress ENSG00000128272 ENSG00000171791 ENSG00000127191 PMC3906332__F4 Reprogramming of non-genomic estrogen signaling by the stemness factor SOX2 enhances the tumor-initiating capacity of breast cancer cells ENSG00000171105 ENSG00000198793 PMC7255038__F3 Schematic diagram representing interplay between metabolism and epigenetics ENSG00000151376 ENSG00000065833 ENSG00000147162 ENSG00000077463 ENSG00000096717 ENSG00000082212 PMC3575604__F1 Evolution and impact of subclonal mutations in chronic lymphocytic leukemia ENSG00000149311 ENSG00000127948 PMC9405286__F1 Effects and Mechanisms of Curcumin for the Prevention and Management of Cancers: An Updated Review ENSG00000149311 ENSG00000135446 ENSG00000170558 ENSG00000198793 ENSG00000144848 ENSG00000072274 ENSG00000168036 ENSG00000172936 ENSG00000136869 ENSG00000168610 ENSG00000146648 PMC9503837__F2 Histone acetylation dynamics in repair of DNA double-strand breaks ENSG00000149311 PMC5037390__F6 Hypothetical mechanistic network derived from predicted upstream regulators for genes found to be differentially expression in chondrocytes in transition from monolayer to alginate bead cultures (redifferentiation) ENSG00000139219 ENSG00000081041 ENSG00000128272 ENSG00000125398 ENSG00000116044 ENSG00000100906 ENSG00000177606 ENSG00000136235 ENSG00000162772 PMC6710759__F1 Schematic KEGG map representations of signaling pathways involved in Alzheimer's disease (a), Parkinson's disease (b), and amyotrophic lateral sclerosis (c) ENSG00000132906 ENSG00000142192 ENSG00000277586 ENSG00000141401 ENSG00000002330 ENSG00000100285 ENSG00000173992 ENSG00000120868 ENSG00000119912 ENSG00000164305 PMC9398942__F5 Utility of NO and H2S donating platforms in managing COVID-19: Rationale and promise ENSG00000138735 PMC7593920__F3 The HMGB1 signaling pathway ENSG00000189403 ENSG00000007908 ENSG00000185591 PMC8165220__F3 Rac1, A Potential Target for Tumor Therapy ENSG00000087245 ENSG00000138639 ENSG00000104147 ENSG00000120756 ENSG00000070831 ENSG00000140575 ENSG00000168036 ENSG00000111737 ENSG00000075223 ENSG00000149269 ENSG00000177606 ENSG00000118257 ENSG00000160293 ENSG00000204217 PMC3312932__F2 Regulation of the human catalytic subunit of telomerase (hTERT) ENSG00000070444 ENSG00000175189 ENSG00000198793 ENSG00000164362 ENSG00000185591 ENSG00000205250 ENSG00000102974 PMC6662580__F1 Hippo pathway ENSG00000129474 ENSG00000113645 ENSG00000166167 ENSG00000126016 ENSG00000130545 ENSG00000101109 ENSG00000160551 ENSG00000131503 ENSG00000044115 ENSG00000132466 ENSG00000064393 ENSG00000139926 ENSG00000114978 ENSG00000150457 ENSG00000119383 ENSG00000132849 ENSG00000131023 ENSG00000068028 ENSG00000132471 ENSG00000186575 ENSG00000143514 ENSG00000169435 PMC8978518__F9 Therapeutic potential of the human endogenous retroviral envelope protein HEMO: a pan‐cancer analysis ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000198125 ENSG00000168646 PMC2442833__F1 Metabolic network of oryza sativa L ENSG00000159224 ENSG00000122966 ENSG00000172005 PMC6585737__F1 Receptors and signaling pathways mainly contributing to anti‐inflammatory polarization of microglia ENSG00000167601 ENSG00000086991 ENSG00000168610 PMC3996671__F1 Ras and autophagy in cancer development and therapy ENSG00000177169 ENSG00000198793 ENSG00000057663 PMC9471064__F4 Naturally derived indole alkaloids targeting regulated cell death (RCD) for cancer therapy: from molecular mechanisms to potential therapeutic targets ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC6585737__F3 Metabolic drugs and molecular pathways exploitable to drive microglia into a pro‐regenerative phenotype ENSG00000172680 ENSG00000118520 ENSG00000096717 PMC9471064__F5 Naturally derived indole alkaloids targeting regulated cell death (RCD) for cancer therapy: from molecular mechanisms to potential therapeutic targets ENSG00000177169 ENSG00000110497 ENSG00000123395 ENSG00000126775 ENSG00000198793 ENSG00000144848 PMC2758611__F6 Schematic presentation of the proposed TGFB signaling alteration that promotes HNSCC in mice PMC4724815__F6 Long non‐coding RNA urothelial cancer‐associated 1 promotes bladder cancer cell migration and invasion by way of the hsa‐miR‐145–ZEB1/2–FSCN1 pathway ENSG00000169554 ENSG00000170558 PMC3444139__F3 NFKB signaling pathway in ATL ENSG00000104856 ENSG00000173039 ENSG00000111321 PMC8740004__F6 FOXA1 can be modulated by HDAC3 in the progression of epithelial ovarian carcinoma ENSG00000171720 ENSG00000168036 ENSG00000129514 PMC4689294__F1 Wnt canonical and non-canonical pathways ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000100592 ENSG00000134982 PMC4049685__F2 Colorectal cancer metastasis signaling pattern ENSG00000107404 ENSG00000002330 ENSG00000138798 ENSG00000163914 ENSG00000177606 ENSG00000136997 ENSG00000158825 ENSG00000132478 ENSG00000205250 ENSG00000146648 PMC6947613__F1 Molecules and pathways involved in the effect of statins on NO production by endothelial cells ENSG00000163914 ENSG00000132693 PMC2834303__F9 PI3K-Akt pathway negatively regulates LPS signaling and gene expression in mouse macrophages by inhibiting the activation of MAPKs PMC4568768__F1 FSH signaling PMC4022041__F3 Genes involved in the TGF beta signaling pathway after 5 days ENSG00000100387 ENSG00000156574 ENSG00000137801 PMC4279731__F7 RBP-J acts as a master regulator that maintains the identity of the JG cell ENSG00000141448 ENSG00000075142 ENSG00000162897 ENSG00000141052 ENSG00000285485 ENSG00000136826 ENSG00000213145 PMC5992182__F6 RIP1 protects melanoma cells from apoptosis induced by BRAF/MEK inhibitors ENSG00000157764 ENSG00000083799 PMC8812234__F6 IRF-2 inhibits cancer proliferation by promoting AMER-1 transcription in human gastric cancer ENSG00000184675 ENSG00000026508 ENSG00000168036 PMC8082456__F1 Key Role of NAD+ in Anti-Tumor Immune Response: An Update ENSG00000164430 PMC8481577__F6 TNF-Alpha Pathway Alternation Predicts Survival of Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer ENSG00000169245 ENSG00000138755 PMC3824101__F1 Mechanisms involved in type I IFN production and its receptor signaling ENSG00000213928 ENSG00000167207 ENSG00000106100 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000136869 ENSG00000172936 ENSG00000026103 ENSG00000164342 PMC8070209__F10 Pathway involved in the synthetic lethality of PARPi with combination of cisplatin on Twist knockdown CisR OC cells ENSG00000132906 ENSG00000164305 PMC5058735__F9 Growth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation ENSG00000078900 ENSG00000136997 ENSG00000116990 PMC3754247__F2 Oncometabolites: linking altered metabolism with cancer ENSG00000100412 ENSG00000172005 ENSG00000079999 PMC4939268__F1 Metabolites involved in Glycolysis and Amino Acid Metabolism are Altered in Short Children Born Small for Gestational Age ENSG00000281877 ENSG00000100033 PMC7471342__F1 Top 25 mRNA-hub genes in baseline analysis ENSG00000143799 ENSG00000291931 ENSG00000142192 ENSG00000165119 ENSG00000105193 ENSG00000164587 ENSG00000089157 ENSG00000074319 ENSG00000168036 ENSG00000278270 ENSG00000174444 ENSG00000132170 ENSG00000160691 ENSG00000123124 ENSG00000008988 ENSG00000078747 ENSG00000010810 ENSG00000113558 ENSG00000177606 ENSG00000149273 ENSG00000159352 ENSG00000099804 ENSG00000146648 PMC8810966__F12 Sex- and estrous-cycle dependent dorsal hippocampal phosphoproteomic changes induced by low-dose ketamine ENSG00000157764 ENSG00000166278 ENSG00000128602 ENSG00000095794 PMC9170928__F8 Chicken telomerase reverse transcriptase mediates LMH cell pyroptosis by regulating the nuclear factor-kappa B signaling pathway ENSG00000162711 ENSG00000111537 ENSG00000125538 ENSG00000167914 PMC11994599__F9 Salvia miltiorrhiza Bunge root in the treatment of myocardial fibrosis: research progress and challenges ENSG00000086991 ENSG00000172936 ENSG00000136869 PMC11687105__F1 M(6)A biological functions ENSG00000120833 ENSG00000157404 ENSG00000168743 ENSG00000165643 ENSG00000163739 ENSG00000198492 ENSG00000114737 ENSG00000198793 ENSG00000196468 ENSG00000169710 ENSG00000057663 ENSG00000070756 ENSG00000164944 ENSG00000149658 ENSG00000124574 ENSG00000122008 PMC11994599__F7 Salvia miltiorrhiza Bunge root in the treatment of myocardial fibrosis: research progress and challenges ENSG00000170365 ENSG00000087245 ENSG00000120693 ENSG00000100985 PMC11687105__F2 Therapeutic potential of RNA m(6)A in lung cancer ENSG00000100234 ENSG00000120833 ENSG00000198492 ENSG00000198793 ENSG00000091542 ENSG00000101447 ENSG00000146457 ENSG00000172795 ENSG00000136231 ENSG00000141867 ENSG00000122691 ENSG00000149658 ENSG00000169750 ENSG00000105991 ENSG00000047188 ENSG00000073792 ENSG00000037280 ENSG00000283060 ENSG00000145782 ENSG00000165819 ENSG00000188486 ENSG00000145388 ENSG00000092439 ENSG00000151012 ENSG00000158828 ENSG00000092199 ENSG00000138759 ENSG00000167900 ENSG00000126787 ENSG00000187134 ENSG00000079999 ENSG00000122566 ENSG00000094804 ENSG00000164944 ENSG00000099326 ENSG00000083799 ENSG00000152952 PMC3760860__F6 Organized Emergence of Multiple-Generations of Teeth in Snakes Is Dysregulated by Activation of Wnt/Beta-Catenin Signalling ENSG00000138795 PMC8173116__F2 Monochromatic Lighting During Incubation and Vaccination on the Splenic Transcriptome Profiles of Chicken ENSG00000141086 ENSG00000133466 ENSG00000185615 PMC7922079__F4 Targeting EPC expansion as a novel therapeutic strategy ENSG00000102145 ENSG00000129167 ENSG00000198793 PMC8801576__F8 Agrin Promotes Non-Small Cell Lung Cancer Progression and Stimulates Regulatory T Cells via Increasing IL-6 Secretion Through PI3K/AKT Pathway ENSG00000111537 ENSG00000105329 PMC12055897__F2 LncRNAs and IgA nephropathy: underlying molecular pathways and clinical applications ENSG00000177606 PMC12055897__F5 LncRNAs and IgA nephropathy: underlying molecular pathways and clinical applications ENSG00000138798 ENSG00000146648 PMC4668540__F1 Sonic Hedgehog Pathway ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC7075017__F1 Fanconi anemia pathway of DNA repair ENSG00000143799 ENSG00000183763 ENSG00000138346 ENSG00000144554 ENSG00000187741 ENSG00000197299 ENSG00000051180 ENSG00000276787 ENSG00000177084 PMC3998839__F1 mTORC1 is a component of mTOR that is directly inhibited by rapamycin and rapamycin derivatives like everolimus ENSG00000002330 ENSG00000138798 ENSG00000284161 ENSG00000171791 PMC7862491__F2 Expanding the role of proteasome homeostasis in Parkinson’s disease: beyond protein breakdown ENSG00000197312 ENSG00000115415 ENSG00000125347 ENSG00000106459 ENSG00000079999 PMC6382377__F1 Lymphopenia and DMTs for relapsing forms of MS ENSG00000105656 ENSG00000102967 PMC7999163__F2 Possible mechanisms through which the gut microbiota could affect the homeostatic and hedonic pathways ENSG00000173599 ENSG00000198576 ENSG00000131096 PMC8169406__F5 Strategies to restore NO bioactivity ENSG00000130234 ENSG00000145321 PMC6352225__F6 Schematic illustration of the role of human papilloma virus (HPV) oncoproteins in the production of macrophage migration inhibitory factor (MIF) ENSG00000198793 PMC7354740__F1 Leptin action in granulosa cells ENSG00000169047 PMC7261627__F2 New insights into progesterone receptor signaling in the endometrium required for embryo implantation ENSG00000162552 ENSG00000164736 ENSG00000082175 ENSG00000060237 ENSG00000150907 ENSG00000164107 ENSG00000128602 ENSG00000179348 ENSG00000146648 PMC8724833__F7 Schematic figure of the action of OASL in pulmonary viral infection ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000135114 ENSG00000107485 ENSG00000172936 ENSG00000175104 ENSG00000276561 ENSG00000164342 ENSG00000106546 PMC12158553__F1 Cellular heterogeneity between OA patients and non-OA controls ENSG00000177575 ENSG00000019582 ENSG00000107562 ENSG00000026508 ENSG00000115718 ENSG00000266524 ENSG00000170891 PMC6718311__F1 Pro-apoptotic JNK pathway is strictly restricted in neurons ENSG00000280962 ENSG00000002330 ENSG00000135116 ENSG00000104081 PMC4685734__F5 Apoptotic cell recognition receptors and scavenger receptors ENSG00000145794 ENSG00000141968 PMC8935239__F9 Icariside II enhances cisplatin-induced apoptosis by promoting endoplasmic reticulum stress signalling in non-small cell lung cancer cells ENSG00000128272 ENSG00000144895 PMC4685734__F6 Apoptotic cell recognition receptors and scavenger receptors ENSG00000145794 PMC5335589__F5 The extrinsic pathway of the coagulation cascade was investigated in our study ENSG00000115008 ENSG00000003436 ENSG00000110799 PMC7010798__F7 Immunological history governs human stem cell memory CD4 heterogeneity via the Wnt signaling pathway ENSG00000087095 ENSG00000162337 ENSG00000070831 ENSG00000020633 ENSG00000174804 ENSG00000168036 ENSG00000104332 ENSG00000132170 ENSG00000159216 ENSG00000120057 ENSG00000177606 ENSG00000112655 ENSG00000276799 PMC11487499__F2 SPOCK1 promotes cancer occurrence by inducing the PI3K/Akt signaling pathway (by Figdraw) ENSG00000128272 ENSG00000092621 ENSG00000135069 PMC9548471__F1 Genetic backbone of ankylosing spondylitis: how knowledge of genetic susceptibility informs our understanding and management of disease ENSG00000105397 ENSG00000168610 PMC3572392__F4 Almost all Theileria annulata proteins involved in glycolysis and citric acid cycle were identified in the study ENSG00000173599 ENSG00000105953 ENSG00000062485 PMC5124549__F1 Redox Biology and the Interface Between Bioenergetics, Autophagy and Circadian Control of Metabolism ENSG00000115548 ENSG00000147162 PMC3984540__F6 S1P induced changes in epithelial ovarian cancer proteolysis, invasion, and attachment care mediated by Gi and Rac ENSG00000087245 ENSG00000170558 ENSG00000163914 PMC11988162__F1 Illustration of the MAPK (left) and JAK/STAT (right) signaling pathways ENSG00000070831 ENSG00000081237 ENSG00000163914 ENSG00000177606 ENSG00000136997 PMC11274390__F1 Zn and Cu in the synapse under physiological and pathophysiological conditions: (A) Roles of Zn and Cu under normal physiological conditions ENSG00000142192 ENSG00000087250 PMC6358740__F6 Facets of Theiler’s Murine Encephalomyelitis Virus-Induced Diseases: An Update ENSG00000144895 ENSG00000102871 ENSG00000172936 ENSG00000131323 ENSG00000168040 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC3478307__F2 Toll-like receptors, signaling adapters and regulation of the pro-inflammatory response by PI3K ENSG00000140992 ENSG00000172936 ENSG00000175104 PMC9094075__F1 Drug resistance in targeted cancer therapies with RAF inhibitors ENSG00000157764 ENSG00000138798 ENSG00000146648 PMC7282681__F2 Schisandra chinensis on Alzheimer's disease signaling pathway ENSG00000132906 ENSG00000142192 ENSG00000002330 ENSG00000120868 ENSG00000168040 ENSG00000119912 ENSG00000164305 PMC3805993__F2 Novel KP/KISS1R signaling pathways in breast cancer cells lacking the estrogen receptor, ERA ENSG00000140575 ENSG00000170558 ENSG00000100985 ENSG00000146648 PMC3104724__F2 This figure outlines the role of KLF10 protein as a target and as a regulator of the TGFBeta-Smad 2,3 signaling pathway ENSG00000155090 PMC8869601__F6 Potential Citrate Shunt in Erythrocytes of PKAN Patients Caused by Mutations in Pantothenate Kinase 2 ENSG00000131473 ENSG00000087299 PMC7268922__F3 Function pathway analysis between COPD and the two genes: CD38 and TNFRSF12A ENSG00000111537 ENSG00000105329 ENSG00000133116 ENSG00000138798 ENSG00000125538 ENSG00000189403 ENSG00000006327 ENSG00000096717 ENSG00000164305 PMC3175639__F2 Clock-cancer connection in Non-Hodgkin’s Lymphoma: a genetic association study and pathway analysis of the circadian gene Cryptochrome 2 ENSG00000111537 ENSG00000117228 ENSG00000265972 ENSG00000205413 ENSG00000086548 ENSG00000011590 ENSG00000150630 PMC5559046__F3 Cooperation of 20HE, IS, and TOR signaling pathways in the regulation of fly larva growth and development ENSG00000105251 ENSG00000125968 PMC6601021__F1 Activation of the UPR pathway in tumor cells ENSG00000100220 ENSG00000128272 ENSG00000144895 PMC3657461__F3 PI3K/AKT signaling in prostate cancer ENSG00000108691 ENSG00000170558 PMC3657461__F4 The JAK/STAT signaling in prostate cancer ENSG00000012048 ENSG00000162772 ENSG00000168610 PMC5767254__F1 myomiRs and muscle mass wasting and atrophy pathways ENSG00000100811 ENSG00000122691 ENSG00000198793 ENSG00000072274 ENSG00000168036 ENSG00000102468 ENSG00000187840 ENSG00000163412 PMC3657461__F5 ERK and PI3K activation and their crosstalk ENSG00000002330 ENSG00000177606 PMC5767254__F2 Exosomal microRNAs (miRNAs), proteins, and muscle mass wasting ENSG00000172936 ENSG00000175104 ENSG00000145782 ENSG00000184216 PMC3657461__F6 TGFB/SMAD signaling pathway and its implication in prostate cancer ENSG00000163217 PMC3657461__F7 Wnt signaling and its implications in the development of prostate cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC8104964__F1 TLR4 signaling pathways ENSG00000171855 ENSG00000243414 ENSG00000169245 ENSG00000183735 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000127666 ENSG00000276561 PMC2729321__F3 Is NFKB a good target for cancer therapy? Hopes and pitfalls ENSG00000104856 ENSG00000096395 ENSG00000082512 ENSG00000173039 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000127191 PMC3264131__F1 Metabolic pathway of C ENSG00000173599 PMC4591954__F1 Therapeutic targeting of the canonical WNT pathway ENSG00000134982 ENSG00000026508 ENSG00000168036 ENSG00000173273 PMC3657461__F1 Androgen receptor (AR) signaling in prostate cancer ENSG00000138798 ENSG00000168610 PMC5854649__F1 TLR4 signaling pathway ENSG00000170458 ENSG00000125538 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000130159 ENSG00000175104 ENSG00000010671 PMC7765557__F2 Leptin-induced signaling pathways ENSG00000291971 ENSG00000150907 ENSG00000198793 ENSG00000115138 ENSG00000168036 ENSG00000067900 ENSG00000102104 ENSG00000168610 ENSG00000146648 PMC9530148__F3 Astrocytes in neuropathic pain ENSG00000087245 ENSG00000182175 ENSG00000108691 ENSG00000242689 ENSG00000163739 ENSG00000170989 ENSG00000205927 ENSG00000128342 ENSG00000100985 ENSG00000168610 PMC8351219__F4 Molecular mechanisms of action of Nutlins in neuroblastoma cells ENSG00000064393 PMC2597498__F2 TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K–Akt–mTOR signalling pathway ENSG00000198793 ENSG00000164327 PMC2597498__F4 TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K–Akt–mTOR signalling pathway PMC12104071__F2 Research on the role and mechanism of the PI3K/Akt/mTOR signalling pathway in osteoporosis PMC3810594__F1 Renin-angiotensin-aldosterone system and regulation of insulin signaling phosphorylation of docking protein insulin receptor substrate -1 (IRS-1) is the major converging point in insulin signaling ENSG00000169047 ENSG00000198793 PMC6966713__F5 Linear ubiquitination and NFKB activation ENSG00000167207 ENSG00000137275 ENSG00000102871 ENSG00000082512 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC6800142__F7 TGFB receptors activate Smad signaling and non-Smad signal transduction pathways ENSG00000175104 PMC5672637__F10 Schematic diagram for the functional mechanism of Aster glehni extract ENSG00000131473 ENSG00000042832 ENSG00000113161 ENSG00000026103 PMC5668426__F7 AGEs-Cyr61-VEGF pathway observed in this study ENSG00000087245 ENSG00000197713 ENSG00000168610 PMC8817869__F7 Sirt1 Mediates Vitamin D Deficiency-Driven Gluconeogenesis in the Liver via mTorc2/Akt Signaling ENSG00000150907 ENSG00000096717 ENSG00000124253 PMC11547603__F1 Activation of the components of the TGFB/Smad canonical signaling pathway initiates the fibrosis process by inducing transcription of the downstream fibrotic genes PMC11547603__F2 Activation of TGFB stimulates NFKB and MAPK signaling pathways with the subsequent activation of the Wnt/Beta-catenin pathway ENSG00000175104 ENSG00000076604 PMC6368618__F8 Decidual RANKL/RANK interaction promotes the residence and polarization of TGFB1-producing regulatory GD T cells ENSG00000049768 PMC11547603__F3 Activation and interaction of both canonical Wnt signaling and non-canonical Wnt/TGFB ENSG00000134982 PMC4879891__F1 Canonical Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000167074 PMC9141076__F3 An Overlooked Bone Metabolic Disorder: Cigarette Smoking-Induced Osteoporosis ENSG00000140465 ENSG00000131196 ENSG00000106546 PMC11547603__F4 Interaction between non-canonical Wnt/Beta-catenin and TGFB/Smad signaling pathways to stimulate the fibrogenesis process and transcription of the downstream fibrotic genes ENSG00000168036 ENSG00000111186 ENSG00000177283 PMC11547603__F5 An overview of role of TGFB in the pathogenesis of intestinal fibrosis ENSG00000198793 ENSG00000100985 ENSG00000108821 PMC11555136__F5 Signaling pathway involved in the development of persistent bladder hyperalgesia ENSG00000189403 ENSG00000172936 ENSG00000136869 PMC2949659__F1 Tamoxifen metabolic pathway ENSG00000165841 ENSG00000197408 PMC11175075__F1 Jasmonic Acid on Stress Response and Quality Formation in Vegetable Crops and Their Underlying Molecular Mechanisms ENSG00000136997 PMC5897904__F2 Genes mapped to the IL-6 pathway by IPA Software ENSG00000162889 ENSG00000127191 ENSG00000132693 PMC12066244__F7 Action of Osteo‐F in osteoarthritis ENSG00000139219 ENSG00000261857 ENSG00000113520 PMC3462935__F5 Schematic diagram depicting the potential interactions between EGF, S100A11, and Ca2+signaling pathway in human endometrial cell ENSG00000164136 ENSG00000128342 ENSG00000146648 PMC9658491__F4 Molecular and Genetic Mechanisms of Spinal Stenosis Formation: Systematic Review ENSG00000170365 ENSG00000137834 PMC9658491__F5 Molecular and Genetic Mechanisms of Spinal Stenosis Formation: Systematic Review ENSG00000134982 ENSG00000168036 PMC5359577__F10 Signalling mechanisms mediating Zn2+-induced TRPM2 channel activation and cell death in microglial cells ENSG00000227345 PMC8618701__F5 Proteomic Characterization of Plasma Rich in Growth Factors and Undiluted Autologous Serum ENSG00000070831 ENSG00000163914 ENSG00000131095 ENSG00000123143 ENSG00000288461 ENSG00000227345 PMC2043401__F1 Schematic outline of fatty acid synthesis in apicomplexans ENSG00000107798 ENSG00000172005 ENSG00000026103 PMC8627049__F7 Integrated DIA proteomics and lipidomics analysis on non-small cell lung cancer patients with TCM syndromes ENSG00000130164 ENSG00000042832 ENSG00000173599 ENSG00000132855 ENSG00000169174 PMC6237564__F7 Stimulation of autophagy by MAC in lung cancer cells ENSG00000198793 PMC5543726__F2 REV1 and DNA polymerase zeta in DNA interstrand crosslink repair ENSG00000154920 ENSG00000144554 ENSG00000188827 ENSG00000132646 ENSG00000070950 ENSG00000276787 ENSG00000095002 ENSG00000122008 PMC5542201__F3 Effect of rapamycin, NVP-BEZ235, aspirin, and metformin on PI3K/AKT/mTOR signaling pathway of PIK3CA-related overgrowth spectrum (PROS) ENSG00000002330 PMC9549801__F1 Relationship Between Ferroptosis and Diseases ENSG00000168003 ENSG00000151012 ENSG00000196839 ENSG00000167468 ENSG00000111684 ENSG00000115107 PMC12105125__S1 Schematic diagram of this study ENSG00000169245 ENSG00000173599 PMC4779714__F4 Identification of compounds that modulate retinol signaling using a cell-based qHTS assay ENSG00000291971 ENSG00000168610 PMC8418074__F4 Current Insights and Advancements in Head and Neck Cancer: Emerging Biomarkers and Therapeutics with Cues from Single Cell and 3D Model Omics Profiling ENSG00000005339 ENSG00000134982 ENSG00000148400 ENSG00000185479 ENSG00000198793 ENSG00000168610 ENSG00000170465 ENSG00000079999 ENSG00000149311 ENSG00000135446 ENSG00000177606 ENSG00000136997 ENSG00000139687 ENSG00000146648 ENSG00000109670 PMC9134657__F2 New therapeutic targets in ovarian cancer through identifying significantly non-mutated genes ENSG00000136535 ENSG00000167632 ENSG00000165125 ENSG00000185658 ENSG00000127616 PMC7555718__F4 Osteoclasts and Microgravity ENSG00000170909 ENSG00000131196 ENSG00000135605 ENSG00000010671 PMC8946555__F1 Adenosine-Metabolizing Enzymes, Adenosine Kinase and Adenosine Deaminase, in Cancer ENSG00000156110 ENSG00000196839 PMC8914608__F2 Emerging Biomarkers Beyond Leukotrienes for the Management of Nonsteroidal Anti-inflammatory Drug (NSAID)-Exacerbated Respiratory Disease ENSG00000137033 ENSG00000113520 ENSG00000145777 ENSG00000166090 PMC6827304__F5 DAMGO and morphine differentially assemble protein-interaction networks to control MOR spatiotemporal signaling ENSG00000140575 ENSG00000134760 ENSG00000099942 PMC2749695__F4 Guanylyl cyclase C in colorectal cancer: susceptibility gene and potential therapeutic target ENSG00000107779 ENSG00000134982 ENSG00000198793 ENSG00000136997 ENSG00000168036 PMC2749695__F5 Guanylyl cyclase C in colorectal cancer: susceptibility gene and potential therapeutic target ENSG00000103479 ENSG00000002330 ENSG00000198793 ENSG00000136997 ENSG00000096088 ENSG00000168036 ENSG00000001626 PMC2575629__F3 Alternative pathway of NFKB activation ENSG00000162924 ENSG00000111321 ENSG00000131323 PMC7750705__F1 Roles of MGO in modulating cell signaling pathways, host immunity, and antiviral activity ENSG00000105656 ENSG00000159399 PMC4784386__F4 Functional interaction network of the final set of 50 genes prioritized with the consensus strategy and 100 additional interacting genes ENSG00000104884 ENSG00000100883 ENSG00000136937 ENSG00000153037 ENSG00000112118 ENSG00000166508 ENSG00000178537 ENSG00000184752 ENSG00000077312 ENSG00000114503 ENSG00000062485 ENSG00000143977 ENSG00000197713 ENSG00000142192 ENSG00000115561 ENSG00000117152 ENSG00000117906 ENSG00000132170 ENSG00000106459 ENSG00000094804 ENSG00000144935 ENSG00000121481 ENSG00000137992 ENSG00000110435 ENSG00000164695 ENSG00000101421 ENSG00000140319 ENSG00000144028 ENSG00000131495 ENSG00000131165 ENSG00000101266 ENSG00000108061 ENSG00000149295 ENSG00000167881 ENSG00000130724 ENSG00000197265 ENSG00000131876 ENSG00000153767 ENSG00000115942 ENSG00000135336 ENSG00000100504 ENSG00000091140 ENSG00000125166 ENSG00000100994 ENSG00000139343 ENSG00000105953 ENSG00000274442 ENSG00000162385 ENSG00000010810 ENSG00000134686 PMC4784386__F5 Functional interaction network comprising gene sets prioritized by Limma and ML ENSG00000143147 ENSG00000169071 ENSG00000102317 ENSG00000134982 ENSG00000164933 ENSG00000185010 ENSG00000080546 ENSG00000168283 ENSG00000138663 ENSG00000138032 ENSG00000184900 ENSG00000157542 ENSG00000116667 ENSG00000173933 ENSG00000073910 ENSG00000117906 ENSG00000197694 ENSG00000151276 ENSG00000127616 ENSG00000198586 ENSG00000188783 ENSG00000173404 ENSG00000020633 ENSG00000134575 ENSG00000163064 ENSG00000150967 ENSG00000112992 ENSG00000109272 ENSG00000108061 ENSG00000149295 ENSG00000128050 ENSG00000136935 ENSG00000183527 ENSG00000122863 ENSG00000095464 ENSG00000291682 ENSG00000140522 ENSG00000131097 ENSG00000008324 ENSG00000205758 ENSG00000171951 ENSG00000120008 ENSG00000091482 ENSG00000089199 ENSG00000071994 ENSG00000034693 ENSG00000071991 ENSG00000114520 ENSG00000150938 ENSG00000127928 ENSG00000023734 ENSG00000166257 ENSG00000291941 ENSG00000119541 ENSG00000283085 ENSG00000105711 ENSG00000132305 ENSG00000112406 ENSG00000179222 ENSG00000108828 ENSG00000138594 ENSG00000136866 ENSG00000154832 ENSG00000105053 ENSG00000291420 ENSG00000100320 ENSG00000121350 ENSG00000175334 ENSG00000078304 ENSG00000104915 ENSG00000111319 ENSG00000120805 ENSG00000147255 ENSG00000164136 ENSG00000149554 ENSG00000008710 ENSG00000141744 ENSG00000140092 ENSG00000083444 ENSG00000133740 ENSG00000089163 ENSG00000083720 ENSG00000165646 ENSG00000135298 ENSG00000146701 ENSG00000120837 ENSG00000009724 ENSG00000189056 ENSG00000117152 ENSG00000110876 ENSG00000067715 ENSG00000139330 ENSG00000013441 ENSG00000100591 ENSG00000213741 ENSG00000147604 ENSG00000134480 ENSG00000115828 ENSG00000175054 ENSG00000125144 ENSG00000145782 ENSG00000091140 ENSG00000274935 ENSG00000123700 ENSG00000171105 ENSG00000108960 ENSG00000058091 ENSG00000089041 ENSG00000021645 ENSG00000184481 ENSG00000136099 ENSG00000100596 ENSG00000110696 ENSG00000115415 ENSG00000167535 ENSG00000175215 ENSG00000103528 ENSG00000164754 ENSG00000135424 ENSG00000080839 ENSG00000204217 PMC3728089__F5 Cholinergic anti-inflammatory pathway ENSG00000136869 ENSG00000168610 ENSG00000178568 PMC12229708__F7 Uterine stromal MEN1 regulates stromal decidualization and epithelial differentiation ENSG00000151376 ENSG00000164107 ENSG00000146678 PMC5963742__F5 BPA increases downstream survival proteins and GPER while attenuating the growth inhibitory effects of EGFR inhibition ENSG00000146648 PMC5486049__F5 Scheme representing major factors of CWIP and the calcineurin signaling pathway ENSG00000070831 ENSG00000149489 PMC11618518__F4 Macrophages in organ fibrosis ENSG00000108691 ENSG00000125538 ENSG00000131724 ENSG00000121807 PMC11618518__F1 Molecular mechanisms of tissue fibrosis ENSG00000137033 ENSG00000198793 ENSG00000163914 ENSG00000173039 ENSG00000168036 ENSG00000166278 PMC7461575__F4 Integrates stress response (ISR) in the context of muscular disorders ENSG00000116001 ENSG00000128272 PMC8632384__F9 Network Pharmacology-Based Study on Irritable Bowel Syndrome Prevention and Treatment Utilizing Shenling Baizhu Powder ENSG00000168040 PMC8708342__F2 Species-Specific Differences in Aryl Hydrocarbon Receptor Responses: How and Why? ENSG00000106546 PMC5931110__F1 Immune activating and suppressive effects of DNA double-strand break (DSB) signalling ENSG00000149311 ENSG00000175054 ENSG00000125347 PMC9320222__F9 Ferrocene-containing nucleoside analogue targets DNA replication in pancreatic cancer cells ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000276618 ENSG00000113456 ENSG00000104320 ENSG00000132383 ENSG00000051180 ENSG00000139618 PMC3632591__F7 RNA-Seq Profiling Reveals Novel Hepatic Gene Expression Pattern in Aflatoxin B1 Treated Rats ENSG00000262406 ENSG00000107105 ENSG00000117697 ENSG00000178999 ENSG00000164109 ENSG00000101057 ENSG00000112118 ENSG00000135069 ENSG00000143228 ENSG00000145386 ENSG00000076003 ENSG00000166851 ENSG00000135373 ENSG00000124762 ENSG00000139618 ENSG00000198901 ENSG00000129757 ENSG00000277586 ENSG00000144366 ENSG00000118785 ENSG00000026103 ENSG00000143632 PMC7471342__F2 Top 25 mRNA-hub genes in delta analysis ENSG00000115484 ENSG00000142192 ENSG00000135439 ENSG00000167658 ENSG00000074319 ENSG00000121807 ENSG00000171560 PMC3632591__F8 RNA-Seq Profiling Reveals Novel Hepatic Gene Expression Pattern in Aflatoxin B1 Treated Rats ENSG00000087245 ENSG00000142192 ENSG00000114346 ENSG00000138798 ENSG00000127955 ENSG00000196562 ENSG00000143228 ENSG00000112715 ENSG00000092820 ENSG00000183395 ENSG00000109814 ENSG00000138778 ENSG00000198901 ENSG00000196549 ENSG00000148798 ENSG00000149485 ENSG00000001626 PMC8229605__F1 Molecular Perspective of Nanoparticle Mediated Therapeutic Targeting in Breast Cancer: An Odyssey of Endoplasmic Reticulum Unfolded Protein Response (UPRER) and Beyond ENSG00000128272 PMC8623349__F7 Nutrigenomic Effect of Hydroxytyrosol in Vascular Endothelial Cells: A Transcriptomic Profile Analysis ENSG00000162889 ENSG00000175206 ENSG00000104365 ENSG00000196591 ENSG00000065559 ENSG00000168036 ENSG00000132478 ENSG00000141052 ENSG00000166484 ENSG00000135341 ENSG00000137764 ENSG00000120937 ENSG00000187840 ENSG00000159200 ENSG00000150281 ENSG00000092054 ENSG00000177606 ENSG00000136997 ENSG00000128342 ENSG00000184304 PMC8623349__F6 Nutrigenomic Effect of Hydroxytyrosol in Vascular Endothelial Cells: A Transcriptomic Profile Analysis ENSG00000159461 ENSG00000165280 ENSG00000127022 ENSG00000100219 ENSG00000171791 ENSG00000127191 PMC4777991__F1 Regulation of insulin-like growth factor signaling pathway by microRNAs in hepatocellular carcinoma ENSG00000197081 ENSG00000073792 ENSG00000140443 ENSG00000136231 PMC5818278__F2 Synthetic scheme of CS oligosaccharides using enzymes ENSG00000105664 ENSG00000291814 PMC5509150__F4 Genetic variation in the eicosanoid pathway is associated with non-small-cell lung cancer (NSCLC) survival ENSG00000186115 ENSG00000138115 ENSG00000186526 PMC7026059__F5 Dl-3-n-butylphthalide attenuates mouse behavioral deficits to chronic social defeat stress by regulating energy metabolism via AKT/CREB signaling pathway ENSG00000062485 PMC3310225__F10 Protein Kinase A and Wnt-dependent network regulating an intermediate stage in epithelial tubulogenesis during kidney development ENSG00000162552 ENSG00000095794 PMC6600639__F1 Upon T-cell receptor (TCR) signaling, the protein arginine methyltransferase PRMT5 interacts with DUSP14 and induces its methylation on Arg17, Arg38, and Arg45 residues ENSG00000127191 PMC8186314__F1 GLI1: A Therapeutic Target for Cancer ENSG00000157764 ENSG00000164690 ENSG00000128602 PMC6903391__F3 Epigenetic changes induced by iAs ENSG00000214435 ENSG00000116761 PMC5812824__F2 Gonadotropin regulation by pulsatile GnRH: signaling and gene expression ENSG00000136603 ENSG00000109163 PMC11559183__F1 Regular neuregulin 4 (Nrg4)-erb-b2 receptor tyrosine kinase 4 (ErbB4) signaling pathway ENSG00000138798 ENSG00000169752 ENSG00000178568 PMC7916440__F2 Simplified overview of major protective signaling pathways involved in RIPC, the reperfusion injury salvage (RISK) pathway, and the survivor activating factor enhancement (SAFE) pathway ENSG00000002330 ENSG00000168610 PMC9219813__F2 Sphingosine 1-Phosphate Signaling at the Skin Barrier Interface ENSG00000163914 ENSG00000170989 ENSG00000180739 ENSG00000213694 ENSG00000125910 ENSG00000267534 PMC5812824__F1 Gonadotropin regulation by pulsatile GnRH: signaling and gene expression ENSG00000273173 ENSG00000109163 PMC5063512__F6 Schematic showing the mechanism of IGFBP-2-mediated regulation of Beta-catenin pathway in glioma cells involving A5B1 integrin, FAK and GSK3B ENSG00000087245 ENSG00000115457 ENSG00000168036 PMC10514503__F2 S1P maintains the intestinal intraepithelial EC barrier ENSG00000163914 ENSG00000180739 ENSG00000125910 ENSG00000267534 ENSG00000183018 PMC10514503__F3 S1P protects the intestinal barrier through multiple means ENSG00000150782 ENSG00000170989 ENSG00000180739 ENSG00000213694 ENSG00000125910 ENSG00000168610 ENSG00000267534 PMC7102936__F3 mTOR at the nexus of nutrition, growth, ageing and disease ENSG00000177058 ENSG00000052795 ENSG00000239282 ENSG00000146648 ENSG00000285069 PMC9221318__F4 Hedgehog Morphogens Act as Growth Factors Critical to Pre- and Postnatal Cardiac Development and Maturation: How Primary Cilia Mediate Their Signal Transduction ENSG00000106571 ENSG00000291971 ENSG00000198793 ENSG00000128602 PMC9221318__F3 Hedgehog Morphogens Act as Growth Factors Critical to Pre- and Postnatal Cardiac Development and Maturation: How Primary Cilia Mediate Their Signal Transduction ENSG00000106571 ENSG00000128602 PMC9471064__F1 Naturally derived indole alkaloids targeting regulated cell death (RCD) for cancer therapy: from molecular mechanisms to potential therapeutic targets ENSG00000175054 ENSG00000137275 ENSG00000102871 ENSG00000167468 ENSG00000198793 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC9219426__F1 Mitochondrial DNA in dynamics of the immune response to COVID-19 ENSG00000239732 ENSG00000130234 ENSG00000184012 ENSG00000172936 PMC7102936__F5 mTOR at the nexus of nutrition, growth, ageing and disease ENSG00000173599 ENSG00000196712 PMC6831883__F3 Timing Analysis and Its Results for the Citric Acid Cycle(A) Timing analysis ENSG00000122966 ENSG00000141086 ENSG00000183691 ENSG00000172005 PMC6433665__F3 Common alterations in fluorosis‐proliferation and differentiation ENSG00000170365 ENSG00000120693 ENSG00000168036 PMC5166550__F9 Signal pathway of IGF-1 by exercise ENSG00000198793 PMC6315103__F1 ProQ-dependent changes in Salmonella-infected HeLa cells ENSG00000175054 ENSG00000167552 ENSG00000126458 PMC3623009__F1 Simplified scheme of the complement activation network ENSG00000196352 ENSG00000117335 ENSG00000120885 ENSG00000166278 ENSG00000117322 ENSG00000236625 PMC7466665__F3 Role of LPA on Hippo-YAP mediated osteogenesis, angiogenesis and osteoimmunology ENSG00000138755 ENSG00000198670 ENSG00000118520 ENSG00000154188 ENSG00000131023 PMC9456385__F1 Reactive Oxygen Species and Long Non-Coding RNAs, an Unexpected Crossroad in Cancer Cells ENSG00000149311 ENSG00000198793 ENSG00000079999 PMC9221389__F8 Integrated Analysis Reveals S100a8/a9 Regulates Autophagy and Apoptosis through the MAPK and PI3K-AKT Signaling Pathway in the Early Stage of Myocardial Infarction ENSG00000162889 ENSG00000117020 ENSG00000170458 ENSG00000177606 ENSG00000136997 ENSG00000166484 ENSG00000006062 ENSG00000146648 ENSG00000133818 PMC8770807__F1 Hypomethylating Agent-Based Combination Therapies to Treat Post-Hematopoietic Stem Cell Transplant Relapse of Acute Myeloid Leukemia ENSG00000122025 ENSG00000111537 ENSG00000049768 PMC9221389__F9 Integrated Analysis Reveals S100a8/a9 Regulates Autophagy and Apoptosis through the MAPK and PI3K-AKT Signaling Pathway in the Early Stage of Myocardial Infarction ENSG00000132906 ENSG00000159224 ENSG00000163914 ENSG00000095015 ENSG00000172936 ENSG00000150455 PMC4456045__F3 Negative feedback cross talk between PI3KA/Akt and NFKB signaling pathway by a local brief stimulation of TLR9, a potent preconditioning tool for programming the subsequent responses to I/R injuries and stimulation by TLR2, TLR4, or TLR5 ligands ENSG00000183735 ENSG00000239732 ENSG00000100906 ENSG00000170458 ENSG00000131323 ENSG00000175104 PMC4456045__F1 All TLRs signal through the common MyD88-dependent pathway ENSG00000198793 ENSG00000172005 ENSG00000172936 PMC7736343__F7 An autoregulatory feedback loop of miR-21/VMP1 is responsible for the abnormal expression of miR-21 in colorectal cancer cells ENSG00000112561 ENSG00000168610 ENSG00000062716 PMC3036178__F1 Lymphotoxin and the immediate tumor necrosis factor (TNF) family ENSG00000104856 ENSG00000111321 ENSG00000131323 ENSG00000127191 PMC8883113__F6 Prognostic Value of the Developmental Gene FZD6 in Young Saudi Breast Cancer Patients: A Biomarkers Discovery and Cancer Inducers OncoScreen Approach ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC2882741__F1 Schematic view of the GSL metabolism pathways ENSG00000257218 ENSG00000102172 PMC4045475__F1 MUC1: A Novel Metabolic Master Regulator ENSG00000083857 ENSG00000135423 ENSG00000135218 ENSG00000078237 PMC9409325__F8 Tumor Necrosis Factor-Alpha-Induced C-C Motif Chemokine Ligand 20 Expression through TNF Receptor 1-Dependent Activation of EGFR/p38 MAPK and JNK1/2/FoxO1 or the NFKB Pathway in Human Cardiac Fibroblasts ENSG00000146648 ENSG00000115009 PMC4045475__F3 MUC1: A Novel Metabolic Master Regulator ENSG00000083857 ENSG00000135423 ENSG00000135218 PMC11931058__F8 Distribution of key targets in the most relevant pathways ENSG00000087095 ENSG00000087245 ENSG00000127445 ENSG00000170458 ENSG00000102871 ENSG00000135446 ENSG00000138798 ENSG00000007908 ENSG00000127191 ENSG00000168610 ENSG00000081189 ENSG00000026103 PMC3724940__F5 Transcriptomic Analysis of Insulin-Sensitive Tissues from Anti-Diabetic Drug Treated ZDF Rats, a T2DM Animal Model ENSG00000107562 ENSG00000171503 ENSG00000163159 ENSG00000156885 ENSG00000163528 ENSG00000166136 ENSG00000164405 ENSG00000110717 ENSG00000112695 ENSG00000138029 ENSG00000179091 ENSG00000178741 ENSG00000004779 ENSG00000101365 ENSG00000165264 ENSG00000110693 ENSG00000130312 ENSG00000273607 ENSG00000113812 ENSG00000283018 ENSG00000120533 ENSG00000213619 ENSG00000159685 ENSG00000186010 ENSG00000106153 ENSG00000165775 ENSG00000099795 PMC4602285__F7 The role of miR-19b in the inhibition of endothelial cell apoptosis and its relationship with coronary artery disease ENSG00000120868 ENSG00000164305 PMC6278438__F4 pathway of miRNA processing to regulate mRNA decay ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC8156356__F2 Sweet Cherries as Anti-Cancer Agents: From Bioactive Compounds to Function ENSG00000198793 ENSG00000173039 ENSG00000168040 ENSG00000168610 PMC3135880__F5 Survival and proliferative effects of Dilong extract on RSC96 Schwann cell ENSG00000132646 ENSG00000122194 ENSG00000140443 PMC8046396__F2 PPI network of HT consists of 43 nodes, 234 edges, an average node degree of 17, and a high-confidence interaction (0.7; ) ENSG00000168036 ENSG00000205250 ENSG00000118971 ENSG00000124762 ENSG00000132170 ENSG00000103479 ENSG00000167772 ENSG00000129757 ENSG00000132646 ENSG00000136997 ENSG00000159346 ENSG00000285070 ENSG00000133961 ENSG00000114315 ENSG00000139687 ENSG00000080839 PMC4417587__F1 Metabolic pathways associated with 5-HT ENSG00000072210 ENSG00000262635 ENSG00000139287 ENSG00000129167 ENSG00000162882 ENSG00000241644 ENSG00000183077 ENSG00000188676 PMC7359717__F1 Synthesis and release of ACh by tuft cells ENSG00000114200 ENSG00000214415 ENSG00000087085 ENSG00000070985 ENSG00000137841 PMC4123572__F6 Putative inhibitory pathway of the Cp-BF-mediated anti-inflammatory response ENSG00000291971 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000164342 PMC11009220__F2 Interplay of aging, adipose tissue, and COVID-19: a potent alliance with implications for health ENSG00000183735 ENSG00000088888 ENSG00000130234 ENSG00000172936 ENSG00000175104 ENSG00000276561 PMC2828612__F1 Putative mechanism by which the UPS acts downstream of BDNF/TrkB signaling to ultimately regulate Alpha-synuclein aggregation ENSG00000168040 ENSG00000026103 PMC8834953__F3 Renoprotective Effects of Mangiferin: Pharmacological Advances and Future Perspectives ENSG00000162711 ENSG00000125538 ENSG00000189403 PMC8566112__F4 Peroxisomal biogenesis pathway ENSG00000142655 ENSG00000124587 ENSG00000288217 ENSG00000157911 ENSG00000108733 ENSG00000162928 ENSG00000034693 ENSG00000121680 PMC8566112__F5 Peroxisomal Beta-oxidation pathway ENSG00000161533 ENSG00000117528 ENSG00000173208 PMC8566112__F6 Ether lipid synthetic pathway ENSG00000018510 ENSG00000198670 ENSG00000116906 ENSG00000109016 ENSG00000197601 PMC8080614__F1 Glutamine metabolic pathways ENSG00000125166 ENSG00000135423 ENSG00000166123 ENSG00000070669 PMC12102898__F5 Diverse E3 ligases participate in the modulation of multiple signaling pathways via the ubiquitination process, playing crucial roles in either immunological activation or immune evasion through specific mechanisms ENSG00000143799 ENSG00000029363 ENSG00000132109 ENSG00000080802 ENSG00000183735 ENSG00000188554 ENSG00000135446 ENSG00000119401 ENSG00000121067 ENSG00000173926 ENSG00000105810 ENSG00000168610 PMC12102898__F3 NFKB signaling pathway processes and associated ubiquitination ENSG00000104856 ENSG00000102871 ENSG00000111321 ENSG00000127191 ENSG00000078747 ENSG00000186716 ENSG00000082512 ENSG00000197943 ENSG00000172936 ENSG00000131323 ENSG00000075240 ENSG00000124181 ENSG00000175104 ENSG00000184216 PMC5923348__F3 Intricate relationship between CD30 and AP-1 in Classical Hodgkin Lymphoma (CHL) and Anaplastic Large Cell Lymphoma (ALCL) ENSG00000156127 ENSG00000131323 ENSG00000127191 PMC5877576__F11 EGFR multimerization and signaling, illustrating how carbohydrate-binding proteins or carbohydrate-transferases can directly affect transmembrane receptor signal transduction ENSG00000138798 ENSG00000146648 PMC12102898__F4 HBV virus structure and related immune ubiquitination process involving HBx protein ENSG00000072571 ENSG00000069869 ENSG00000134982 ENSG00000137699 ENSG00000168036 ENSG00000175104 ENSG00000147854 PMC12102898__F1 PI3K/Akt and Ras/MAPK signaling pathway processes and associated ubiquitination ENSG00000012048 ENSG00000069869 ENSG00000121067 ENSG00000175104 ENSG00000291501 ENSG00000109670 PMC12102898__F2 Wnt/Beta-catenin signaling pathway processes and associated ubiquitination ENSG00000118518 ENSG00000134982 ENSG00000168036 ENSG00000108375 ENSG00000141569 PMC6566956__F2A Unfolded Protein Response (UPR) in Survival, Dormancy, Immunosuppression, Metastasis, and Treatments of Cancer Cells ENSG00000128272 ENSG00000144895 PMC8978805__F2 Impact of anti-inflammatory agents on oncogenic pathways ENSG00000096996 ENSG00000107562 ENSG00000138336 ENSG00000088305 ENSG00000198793 ENSG00000136997 ENSG00000181555 ENSG00000145777 ENSG00000292363 ENSG00000168610 ENSG00000121966 ENSG00000163507 PMC7904157__F5 SlKLUH expression is associated with genes involved in ‘Cutin synthesis and transport’ pathway PMC10458925__F1 EGFR/PI3K/AKT/mTOR signaling pathway ENSG00000155792 ENSG00000146648 PMC5551366__F12 Mitogen-activated protein kinase signaling pathway ENSG00000087095 ENSG00000172680 ENSG00000170458 ENSG00000130159 ENSG00000196712 PMC3534167__F2 Hodgkin lymphoma ENSG00000104856 ENSG00000100906 ENSG00000118503 ENSG00000162924 ENSG00000083799 PMC8509779__F1 Coagulopathies after Vaccination against SARS-CoV-2 May Be Derived from a Combined Effect of SARS-CoV-2 Spike Protein and Adenovirus Vector-Triggered Signaling Pathways ENSG00000134982 ENSG00000130234 ENSG00000162692 ENSG00000168610 PMC8080614__F5 Glutamine oncometabolites and energy production from glutamine ENSG00000125166 ENSG00000042832 ENSG00000146701 ENSG00000079999 PMC10367567__F1 CXCL12-CXCR4/CXCR7 signaling pathway ENSG00000107562 ENSG00000002330 ENSG00000134982 ENSG00000168036 ENSG00000121966 PMC7792119__F9 Schematic diagram for the functions and mechanism of linc00887 in regulation of cervical cancer ENSG00000139926 ENSG00000150457 ENSG00000131023 PMC3995293__F5 Oxidative Stress-Associated Protein Tyrosine Kinases and Phosphatases in Fanconi Anemia ENSG00000149311 ENSG00000175054 ENSG00000111537 ENSG00000115415 PMC3209293__F6 IA30-infected pigs fail to induce immune response genes associated with pattern recognition of viruses and cytokine and immune cell responses in the lung ENSG00000171855 ENSG00000011600 ENSG00000115267 ENSG00000043462 ENSG00000105639 ENSG00000158869 ENSG00000276561 ENSG00000010671 ENSG00000095585 ENSG00000169245 ENSG00000172936 ENSG00000213809 ENSG00000155629 ENSG00000140443 PMC4620423__F1 Core signaling pathways in embryonic stem cells and cancer stem cells ENSG00000170365 ENSG00000168283 ENSG00000134982 ENSG00000156574 ENSG00000168036 ENSG00000128342 ENSG00000128602 ENSG00000168610 PMC8481630__F7 BRCC3 Promotes Tumorigenesis of Bladder Cancer by Activating the NFKB Signaling Pathway Through Targeting TRAF2 ENSG00000185515 ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC12108521__F1 Molecular mechanisms of ferroptosis and key regulatory pathways ENSG00000167468 ENSG00000111684 ENSG00000115107 PMC3180440__F2 Regulation of the early myogenic transcriptional program by the kinome ENSG00000159224 ENSG00000135446 ENSG00000150907 ENSG00000123374 ENSG00000105810 PMC3180440__F3 Regulation of the late myogenic transcriptional program by the kinome ENSG00000136807 ENSG00000005882 ENSG00000170558 ENSG00000198793 ENSG00000168036 PMC5620322__F1 PRAS40 signaling in tumor ENSG00000169047 ENSG00000137193 PMC6018527__F1 Sema4D/Plexin-B1 signaling ENSG00000106683 ENSG00000172602 ENSG00000067900 ENSG00000187764 ENSG00000124181 ENSG00000126458 PMC4871423__F6 Integrated and Functional Genomics Analysis Validates the Relevance of the Nuclear Variant ErbB380kDa in Prostate Cancer Progression ENSG00000186810 ENSG00000006062 ENSG00000179348 ENSG00000138398 ENSG00000169375 PMC6636438__F2 Schematic model of ROS-activated signaling involved in the rapid modulation of NGB levels, its localization, and function on the redox balance outside mitochondria ENSG00000181019 ENSG00000023909 PMC5582379__F3 Five enriched pathways and their contributing DEGs are shown ENSG00000228716 ENSG00000131153 ENSG00000291964 ENSG00000163918 ENSG00000166508 ENSG00000138778 ENSG00000103479 ENSG00000112242 ENSG00000150991 ENSG00000136997 ENSG00000123374 ENSG00000014138 ENSG00000177084 ENSG00000147536 ENSG00000182628 ENSG00000277909 ENSG00000115163 ENSG00000143228 ENSG00000117399 ENSG00000123219 ENSG00000117724 ENSG00000145604 ENSG00000135446 ENSG00000132646 ENSG00000133119 ENSG00000120334 ENSG00000138092 ENSG00000115307 PMC6032286__F1 Neuromuscular junction and congenital myasthenic syndromes ENSG00000138078 ENSG00000206561 ENSG00000198380 ENSG00000134569 ENSG00000119523 ENSG00000030304 ENSG00000172269 ENSG00000087085 ENSG00000172339 ENSG00000139190 ENSG00000197467 ENSG00000143858 PMC7038066__F2 Proposed model of NO-dependent protein–protein interactions underlying GluA1 and GluA2 subunits’ trafficking ENSG00000198576 PMC12245701__F2 TGFB inhibitors: the future for prevention and treatment of liver fibrosis? ENSG00000198793 ENSG00000163914 PMC5084677__F8 Proposed model for the accumulation of BRCA1 complexes at DSB sites ENSG00000012048 ENSG00000163961 ENSG00000080345 ENSG00000112130 PMC4137413__F2 Genetics of Pulmonary Arterial Hypertension ENSG00000128829 ENSG00000204217 ENSG00000171303 PMC9294386__F2 HIF-1A in Osteoarthritis: From Pathogenesis to Therapeutic Implications ENSG00000125398 PMC11103679__F1 Direct and indirect mechanisms of androgen signalling ENSG00000291971 PMC5486002__F1 The human 42 Kb INK4-ARF (CDKN2A/B) locus (not to scale) and its participation in two pathways controlling cell-cycling and differentiation ENSG00000135446 ENSG00000105810 PMC4620694__F1 Graphical summary: DNA repair proteins such as DNA-PKcs can be targeted to improve outcomes for patients with ovarian cancer ENSG00000143799 ENSG00000012048 ENSG00000002330 ENSG00000158636 ENSG00000291803 ENSG00000051180 PMC5486002__F5 Examples of two pathways of histone modification by polycomb complexes leading to suppression of selected TSG ENSG00000149311 ENSG00000175054 ENSG00000168283 ENSG00000198901 ENSG00000088305 ENSG00000120057 ENSG00000135446 ENSG00000155011 ENSG00000050165 ENSG00000168036 ENSG00000162521 PMC5564844__F1 Epidermal growth factor receptor (EGFR): A rising star in the era of precision medicine of lung cancer ENSG00000146648 PMC9662188__F2 Caspase-2–dependent activation of de novo lipogenesis ENSG00000130164 ENSG00000116133 ENSG00000172893 ENSG00000167910 ENSG00000169710 ENSG00000163702 PMC3460930__F1 Lovastatin Induces Multiple Stress Pathways ENSG00000128272 ENSG00000144895 ENSG00000198793 ENSG00000162772 ENSG00000146648 PMC9502459__F1 Do or Die: HPV E5, E6 and E7 in Cell Death Evasion ENSG00000002330 ENSG00000102871 ENSG00000127191 ENSG00000026103 PMC4344846__F2A IQGAPs choreograph cellular signaling from the membrane to the nucleus ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000140575 ENSG00000183579 ENSG00000132341 PMC5000066__F9 Proposed model illustrating how KLHL21 modulates the NFKB signaling pathway via targeting IKKB ENSG00000144802 ENSG00000118503 ENSG00000163739 ENSG00000125538 ENSG00000162413 PMC5747948__F9 Comprehensive molecular biomarker identification in breast cancer brain metastases ENSG00000185608 ENSG00000090061 ENSG00000152240 ENSG00000131462 ENSG00000166012 ENSG00000062582 ENSG00000102401 ENSG00000137814 ENSG00000105290 ENSG00000150316 ENSG00000291693 ENSG00000150687 ENSG00000163751 ENSG00000168569 ENSG00000116251 ENSG00000274675 ENSG00000009950 ENSG00000071082 ENSG00000143222 ENSG00000140577 ENSG00000166441 ENSG00000170860 ENSG00000118680 ENSG00000198242 ENSG00000100442 ENSG00000166920 ENSG00000130255 ENSG00000175334 ENSG00000171566 ENSG00000142541 ENSG00000070770 ENSG00000189043 ENSG00000040199 ENSG00000100941 ENSG00000165775 ENSG00000148154 PMC5747948__F6 Comprehensive molecular biomarker identification in breast cancer brain metastases ENSG00000145632 ENSG00000291931 ENSG00000137804 ENSG00000151725 ENSG00000162496 ENSG00000073350 ENSG00000291971 ENSG00000155970 ENSG00000178896 ENSG00000255302 ENSG00000130224 ENSG00000076864 ENSG00000137812 ENSG00000154478 ENSG00000184330 ENSG00000102038 ENSG00000187908 ENSG00000112742 ENSG00000177600 ENSG00000108106 ENSG00000187678 ENSG00000064309 ENSG00000067057 ENSG00000112877 ENSG00000025039 ENSG00000103550 ENSG00000073605 ENSG00000113328 ENSG00000197299 PMC6650613__F1 Schematic representation of the steroidogenesis pathway ENSG00000182585 PMC5747948__F7 Merged network based on eight upstream regulators, of which E2f, ERBB2, IL6, HGF, and RABL6 were in a predicted activation state (z-score > 2) and let-7, TP53, and CDKN2A were in a predicted inhibition state (z-score < - 2) ENSG00000145632 ENSG00000112799 ENSG00000137804 ENSG00000152661 ENSG00000186638 ENSG00000157193 ENSG00000163918 ENSG00000163814 ENSG00000143556 ENSG00000092470 ENSG00000049130 ENSG00000172216 ENSG00000082213 ENSG00000121851 ENSG00000196642 ENSG00000051180 ENSG00000112742 ENSG00000166803 ENSG00000136492 ENSG00000123975 ENSG00000189060 ENSG00000123096 ENSG00000136048 ENSG00000197343 ENSG00000113328 ENSG00000167772 ENSG00000110841 ENSG00000280610 ENSG00000197299 ENSG00000175305 PMC5097364__F4 T3-actions from genomic and non-genomic effects on cell adhesion and differentiation during vertebrate development ENSG00000115415 ENSG00000134982 ENSG00000168036 PMC5747948__F5 Top canonical pathway is entitled, role of BRCA1 in DNA damage response ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000095002 PMC11976366__F6 Quercetin inhibits gefitinib-activated cell death in NSCLC via regulating SHP2/ROS/AMPK/XBP-1/DJ-1 signaling pathway-mediated mitochondrial autophagy ENSG00000162711 ENSG00000164430 PMC5097364__F2 Signaling pathways involved in cell-cell adhesion mediated by E-cadherin in physiological and pathological conditions ENSG00000134982 ENSG00000163914 ENSG00000168036 ENSG00000140859 ENSG00000171540 PMC7246474__F2 Summary of proposed pathogenic mechanisms in TRAPS ENSG00000137275 ENSG00000102871 ENSG00000082512 ENSG00000127191 PMC8899988__F8 Novel HDAC11 inhibitor potentiates the tumoricidal effects of cordycepin against malignant peripheral nerve sheath tumor through the Hippo signaling pathway ENSG00000123416 ENSG00000121621 ENSG00000185591 PMC3747576__F6 Urokinase pathway model ENSG00000122194 ENSG00000104368 PMC3825115__F1 Notch pathway effects on cytoskeletal plasticity ENSG00000166402 ENSG00000133961 PMC11881735__F7 Epigenetic regulation of NFKB and JAK/STAT signaling pathway in SAH ENSG00000171720 ENSG00000172936 ENSG00000162692 ENSG00000175104 ENSG00000168610 ENSG00000136826 PMC5564844__F4 Epidermal growth factor receptor (EGFR): A rising star in the era of precision medicine of lung cancer ENSG00000168610 ENSG00000146648 PMC8919722__F8 PRR-Mediated Immune Response and Intestinal Flora Profile in Soybean Meal-Induced Enteritis of Pearl Gentian Groupers, Epinephelus fuscoguttatus♀ × Epinephelus lanceolatus♂ ENSG00000112977 ENSG00000108691 ENSG00000163739 ENSG00000132478 PMC12139130__F2 An overview of mechanisms of how gut microbiota increases the efficiency of immunotherapies ENSG00000239732 ENSG00000164430 ENSG00000111537 ENSG00000198793 ENSG00000174136 ENSG00000136869 ENSG00000276561 PMC11837068__F7 Schematic diagram illustrating that lncRNA H19 positively regulates S1PR3 expression by disrupting HDAC2/H3K27ac binding in EPCs ENSG00000196591 ENSG00000213694 PMC12139130__F1 Gut microbiota modulation in cancer metabolic reprogramming ENSG00000002330 ENSG00000173039 ENSG00000078237 PMC7432326__F1 Mode of 70-kDa heat shock protein (Hsp70) action inside and outside the cell ENSG00000134982 ENSG00000186716 ENSG00000136869 ENSG00000049768 PMC2174913__F2 Checkpoints activated upon rereplication ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000276618 ENSG00000144554 ENSG00000123374 PMC3308137__F2 miRNAs that promote or inhibit tumorigenesis provide diverse functions within oncogenic and tumor suppressor signaling pathways ENSG00000136158 ENSG00000164056 ENSG00000136997 ENSG00000004897 ENSG00000187772 ENSG00000118971 ENSG00000100065 ENSG00000175305 PMC9354928__F11 Research Progress on the Regulation Mechanism of Key Signal Pathways Affecting the Prognosis of Glioma ENSG00000157764 ENSG00000115415 ENSG00000196712 PMC7998272__F3 Alternate splicing of the LOXL2 mRNA ENSG00000134013 ENSG00000291971 PMC4098619__F1 Schematic diagram representation of some of the pathways regulated by HNF1a ENSG00000005339 ENSG00000132570 ENSG00000139515 ENSG00000168036 ENSG00000166228 PMC5653694__F1 Circadian rhythms are driven by a vast network of oscillators regulated by multiple interconnected feedback loops that, in turn, synchronize the entire organism ENSG00000084093 ENSG00000198576 ENSG00000005381 PMC2989866__F2 The Regulation of the CNS Innate Immune Response Is Vital for the Restoration of Tissue Homeostasis (Repair) after Acute Brain Injury: A Brief Review ENSG00000203710 PMC8051073__F4 Ingenuity Pathway Analysis (IPA), prediction network of the T1DM conditions presented in this study with the upregulation (red) of miR-126-5p, IL-7, TNFA, VEGF-C, CXCR1, CXCR2 and glucose ENSG00000163464 ENSG00000142615 ENSG00000150630 PMC4165197__F4 Action of recombinant bovine somatotropin (rBST) ENSG00000169291 PMC6966813__F3 Ubiquitination on mTOR signal affects the cross-talk between RAS-RAF-MEK and PI3K-AKT-mTOR pathways ENSG00000005882 ENSG00000198793 ENSG00000164327 ENSG00000175104 ENSG00000109670 PMC2728430__F1 How ERK1/2 Activation Controls Cell Proliferation and Cell Death Is Subcellular Localization the Answer? PMC7596389__F10 Probable protective mechanism of UDCA against As(III)-mediated cytotoxicity in vivo and vitro ENSG00000181019 PMC3782845__F4 Possible origin of WM precursors from IgM+ memory cells ENSG00000177455 ENSG00000139193 ENSG00000145321 PMC3782845__F5 MYD88—an intriguing link between WM and natural effector IgM+ memory cells ENSG00000139193 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC1899305__F7 GM-CSF Regulates a PU.1-Dependent Transcriptional Program Determining the Pulmonary Response to LPS ENSG00000170458 ENSG00000172005 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC3110886__F4 Functional analyses of differentially expressed predicted targets of significantly altered microRNAs ENSG00000110514 ENSG00000138326 PMC4316180__F3 Tumor necrosis factor (TNF) induced apoptosis pathway and the Fas-Fas ligand-mediated apoptosis pathway ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC3090136__F1 Prostanoid biosynthesis and response pathway PMC4425560__F7 Berberine Inhibits Invasion and Metastasis of Colorectal Cancer Cells via COX-2/PGE2 Mediated JAK2/STAT3 Signaling Pathway ENSG00000087245 ENSG00000100985 ENSG00000168610 PMC8351877__F4 Treatment With Suboptimal Dose of Benznidazole Mitigates Immune Response Molecular Pathways in Mice With Chronic Chagas Cardiomyopathy ENSG00000186810 ENSG00000138378 ENSG00000111537 ENSG00000165030 ENSG00000144857 ENSG00000197272 ENSG00000020633 ENSG00000107485 ENSG00000168610 PMC3146625__F1 Schematic overview of the steroidogenic pathway ENSG00000086696 ENSG00000151632 ENSG00000242110 ENSG00000133835 ENSG00000203859 ENSG00000197888 ENSG00000169710 ENSG00000196620 ENSG00000187134 PMC4962007__F3 Willin, merlin and ezrin are all FERM containing proteins that can influence proper functioning of the cytoskeleton, cell to cell junction complexes (TJ: tight junctions, AJ: adherens junctions) and the hippo signalling pathway ENSG00000150457 ENSG00000131023 PMC5222873__F4 Nuclear factor Y controls flowering time ENSG00000113600 ENSG00000038002 PMC7389684__F10 Schematic illustration depicting a proposed model of the molecular mechanism of PVT1 in gemcitabine resistance in human pancreatic cancer ENSG00000126775 ENSG00000168036 ENSG00000123908 PMC3682205__F3 Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair ENSG00000069869 ENSG00000198793 PMC6612148__F3 CK2 actions on chaperone machinery (a), NFKB signaling (b), and PI3K/AKT/PTEN pathway (c) ENSG00000148400 ENSG00000105401 PMC9014248__F3 USP13: Multiple Functions and Target Inhibition ENSG00000149311 ENSG00000131473 ENSG00000012048 ENSG00000175054 ENSG00000126775 ENSG00000104969 ENSG00000204463 ENSG00000165280 ENSG00000123374 ENSG00000105953 ENSG00000102178 PMC6445872__F2 In monocytes/macrophages and adipocytes, SIRT1 deacetylates NFKB(p65), resulting in reduced expression of inflammatory mediators such as TNFA and MCP-1 ENSG00000169047 ENSG00000198793 ENSG00000096717 PMC6445872__F5 SIRT6 also attenuates NFKB signaling via histone H3K9 deacetylation at the chromatin level ENSG00000077463 ENSG00000168610 PMC10539544__F1 GLUL gene knockdown and restricted glucose level show synergistic inhibitory effect on the luminal subtype breast cancer MCF7 cells’ proliferation and metastasis ENSG00000111371 ENSG00000115419 PMC4019409__F2 Protein Kinase Signaling at the Crossroads of Myocyte Life and Death in Ischemic Heart Disease ENSG00000102871 ENSG00000047936 ENSG00000168040 ENSG00000283100 PMC2696318__F3 ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE ENSG00000002330 ENSG00000157764 ENSG00000198793 PMC7685642__F2 miRNAsis involved in up-regulation of the bladder cancer ENSG00000155792 PMC2696318__F4 ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE ENSG00000149311 ENSG00000175054 ENSG00000002330 ENSG00000291971 ENSG00000113070 PMC7685642__F3 Resveratrol, curcumin and paclitaxol affects the mTOR pathway at several stages from inhibition to PI3K to suppression of Akt signaling to prevent the mTORC1 and mTORC2 complexes ENSG00000198793 ENSG00000155792 PMC7355854__F1 Simplified scheme of the L-arginine/nitric oxide (NO) pathway ENSG00000081181 ENSG00000118520 ENSG00000007171 PMC7056575__F1 Signaling via the PI3K pathway and inhibition of PGE2 production by NSAIDs ENSG00000002330 PMC2696318__F5 ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE ENSG00000175054 ENSG00000138166 ENSG00000113070 PMC7685642__F1 MTOR signaling cascade ENSG00000143878 ENSG00000198793 ENSG00000163914 ENSG00000164327 PMC2696318__F6 ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE ENSG00000135446 ENSG00000105810 PMC2696318__F7 ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE ENSG00000002330 ENSG00000291971 ENSG00000198793 PMC6360145__F3 Her2 signaling pathway in breast cancers ENSG00000140992 ENSG00000158458 PMC5725018__F6 Gsdma3 regulates hair follicle differentiation via Wnt5a-mediated non-canonical Wnt signaling pathway ENSG00000138795 ENSG00000168036 PMC6568219__F1 Novel insights into cell cycle regulation of cell fate determination ENSG00000149311 ENSG00000135446 ENSG00000105810 PMC5693256__F2A DNA repair after oxidative stress: current challenges ENSG00000143799 PMC11794540__F8 The mechanism by which endothelium-derived AGGF1 attenuates ischaemic retinopathy ENSG00000164252 ENSG00000145386 PMC1895816__F2 Identification of a Bcr-Abl kinase signature ENSG00000157540 ENSG00000186716 ENSG00000198087 ENSG00000250506 ENSG00000163349 PMC6346557__F7 1A,25(OH)2D3 attenuates Il-6 and IL-1Beta-mediated inflammatory responses in MacCM-stimulated human white preadipocytes ENSG00000173039 PMC99889__F13 Erk activation following TCR stimulation ENSG00000291603 ENSG00000213658 PMC8114918__F6 Schematic figure showing the possible contribution of miR-506 to phenotypic presentation of colitis in patients with PSC + UC compared to those with UC alone PMC4767244__F2 NFKB activation pathways ENSG00000104856 ENSG00000149311 ENSG00000175054 ENSG00000111321 PMC4767244__F3 NFKB signaling by oncogenic pathways in GBM ENSG00000149311 ENSG00000111653 ENSG00000083799 ENSG00000146648 ENSG00000196712 PMC6889380__F2 Haem synthesis pathway ENSG00000066926 ENSG00000126088 ENSG00000188690 ENSG00000118777 PMC5214729__F4 Proposed renoprotective mechanisms in diabetic nephropathy (DN) through adenosine monophosphate-activated protein kinase (AMPK) activation ENSG00000266173 ENSG00000198793 ENSG00000113161 ENSG00000106459 PMC8431402__F10 Comparison of the Effects of Resveratrol and Its Derivatives on the Radiation Response of MCF-7 Breast Cancer Cells ENSG00000168040 PMC10685161__F2 Role of AGR2 as a critical regulator of maintaining intestinal barrier function by affecting the intestinal goblet cell differentiation, maturation, and secretion of MUC2 ENSG00000162676 ENSG00000138798 ENSG00000124664 ENSG00000146648 ENSG00000293532 ENSG00000172238 PMC10685161__F3 Effect of UPR-AGR2 signaling pathways on goblet cells during ETEC infection ENSG00000146648 ENSG00000293532 PMC7648344__F1 Activation of MET pathway: pleiotropic effects on cancers through activation of a number of signaling pathways ENSG00000019991 ENSG00000002330 ENSG00000291971 ENSG00000198793 ENSG00000168610 PMC10685161__F1 Major UPR pathways initiated from the ER and the potential role of AGR2 in interacting with EGFR and MUC2 ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 ENSG00000146648 ENSG00000293532 PMC5412772__F1 TRAIL‐ and TNF‐induced signaling complexes—so similar yet so different ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000115718 ENSG00000064012 PMC9478857__F2 Bronchial smooth muscle cell in asthma: where does it fit? PMC7379270__F3 The mTORC1 pathway ENSG00000177169 ENSG00000128272 ENSG00000155792 ENSG00000167965 ENSG00000175104 PMC7379270__F4 The NF‐KB pathway ENSG00000102871 ENSG00000082512 ENSG00000173039 ENSG00000127191 PMC8619803__F1 Alternative Lengthening of Telomeres: Lessons to Be Learned from Telomeric DNA Double-Strand Break Repair ENSG00000143799 ENSG00000284238 ENSG00000138346 ENSG00000188827 ENSG00000187790 ENSG00000121988 ENSG00000035928 ENSG00000127663 ENSG00000144554 ENSG00000132646 ENSG00000197299 ENSG00000138375 ENSG00000140464 PMC11829435__F7 Proposed model showing the mechanism of combined HDAC and FLT3 inhibition ENSG00000149311 ENSG00000122025 ENSG00000183691 ENSG00000051180 ENSG00000174059 PMC4303322__F4 The mammalian DNA damage checkpoint pathways and/or systems ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000276618 PMC7703541__F2 Targeting the renin−angiotensin signaling pathway in COVID-19: Unanswered questions, opportunities, and challenges ENSG00000130234 ENSG00000180772 ENSG00000172938 PMC8072221__F12 Expressional and Prognostic Value of S100A16 in Pancreatic Cancer Via Integrated Bioinformatics Analyses ENSG00000117054 ENSG00000073578 ENSG00000126883 ENSG00000132698 ENSG00000061337 ENSG00000126254 ENSG00000120437 ENSG00000160131 ENSG00000062485 PMC3114474__F1 Mechanisms of Resistance to EGFR TKIs and Development of a New Generation of Drugs in Non-Small-Cell Lung Cancer ENSG00000019991 ENSG00000065361 ENSG00000146648 PMC7094289__F1 TLR signalling - TLR1, TLR2, TLR4, TLR5, TLR6 and TLR10 are expressed on the surface of the cell whereas TLR3, TLR7, TLR8 and TLR9 in intracellular vesicles like endosome and lysosomes ENSG00000172936 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 PMC11012314__F7 Boosting Clear Cell Renal Carcinoma-Specific Drug Discovery Using a Deep Learning Algorithm and Single-Cell Analysis ENSG00000004975 ENSG00000005339 ENSG00000105329 ENSG00000138798 ENSG00000112561 ENSG00000154582 ENSG00000112715 ENSG00000124762 ENSG00000143387 ENSG00000134086 ENSG00000100387 ENSG00000163235 ENSG00000101197 ENSG00000269858 PMC9031790__F3 Regulation of Endoplasmic Reticulum Stress in Cancer: Special Focuses on Luteolin Patents ENSG00000002330 ENSG00000144895 PMC6849114__F6 De Novo Mutations in FOXJ1 Result in a Motile Ciliopathy with Hydrocephalus and Randomization of Left/Right Body Asymmetry ENSG00000214513 ENSG00000148400 ENSG00000152669 ENSG00000129654 ENSG00000234602 PMC9316401__F1 Association between Leptin (G2548A) and Leptin Receptor (Q223R) Polymorphisms with Plasma Leptin, BMI, Stress, Sleep and Eating Patterns among the Multiethnic Young Malaysian Adult Population from a Healthcare University ENSG00000168610 PMC9499815__F8 Trophoblast Exosomal UCA1 Induces Endothelial Injury through the PFN1-RhoA/ROCK Pathway in Preeclampsia: A Human-Specific Adaptive Pathogenic Mechanism ENSG00000074319 ENSG00000159399 ENSG00000101557 PMC11843251__F11 Metrnl/C‐KIT Axis Attenuates Early Brain Injury Following Subarachnoid Hemorrhage by Inhibiting Neuronal Ferroptosis ENSG00000167468 ENSG00000275031 PMC8304079__F1 CAMP in Beta Cell Stimulus–Secretion and Intercellular Coupling ENSG00000196531 ENSG00000159224 ENSG00000102452 ENSG00000146469 ENSG00000180616 ENSG00000070985 ENSG00000121853 ENSG00000010310 ENSG00000164830 PMC3970352__F2 Metabolic pathway of Inflammatory Response in humans ENSG00000134982 PMC8572812__F3 Insulin/IGF-1 signaling promotes immunosuppression via the STAT3 pathway: impact on the aging process and age-related diseases ENSG00000198793 ENSG00000168610 PMC9086828__F3 Microglia in the Neuroinflammatory Pathogenesis of Alzheimer’s Disease and Related Therapeutic Targets ENSG00000135218 ENSG00000159346 PMC9549314__F7 We are all aging, and here's why ENSG00000138777 PMC4917523__F4 Schematic representation of the interplay between the IGF1 signaling axis and p53 genome protection pathway ENSG00000140443 PMC8917441__F7 Prediction of the Active Components and Possible Targets of Xanthii Fructus Based on Network Pharmacology for Use in Chronic Rhinosinusitis ENSG00000142192 ENSG00000080823 PMC2696318__F1 ROLES OF THE RAF/MEK/ERK PATHWAY IN CELL GROWTH, MALIGNANT TRANSFORMATION AND DRUG RESISTANCE ENSG00000169291 PMC8917441__F8 Prediction of the Active Components and Possible Targets of Xanthii Fructus Based on Network Pharmacology for Use in Chronic Rhinosinusitis ENSG00000142192 ENSG00000168040 ENSG00000084774 PMC8811717__F4 Integrated Stress Response, Drug Targets, and Drugs ENSG00000128272 ENSG00000101255 ENSG00000176046 ENSG00000100219 ENSG00000162772 PMC8572812__F1 Insulin/IGF-1 signaling promotes immunosuppression via the STAT3 pathway: impact on the aging process and age-related diseases ENSG00000171105 ENSG00000198793 ENSG00000168610 PMC8572812__F2 Insulin/IGF-1 signaling promotes immunosuppression via the STAT3 pathway: impact on the aging process and age-related diseases ENSG00000198793 ENSG00000118520 ENSG00000168610 PMC9124632__F1 Type-I interferons in the immunopathogenesis and treatment of Coronavirus disease 2019 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000167207 ENSG00000105397 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC9031790__F2 Regulation of Endoplasmic Reticulum Stress in Cancer: Special Focuses on Luteolin Patents ENSG00000128272 ENSG00000100219 PMC9110208__F9 Orcinol Glucoside Improves Senile Osteoporosis through Attenuating Oxidative Stress and Autophagy of Osteoclast via Activating Nrf2/Keap1 and mTOR Signaling Pathway ENSG00000198793 ENSG00000100985 ENSG00000175104 ENSG00000131196 ENSG00000079999 ENSG00000143387 PMC7460314__F2 Key pathway of adipose metabolism ENSG00000042832 ENSG00000026103 PMC6555193__F4 Cancer pathway gene set targeted only by natural products for a cancer driver target ENSG00000116017 ENSG00000165891 ENSG00000123374 ENSG00000145386 ENSG00000124762 ENSG00000129173 ENSG00000175305 PMC1564204__F6 Schematic pathway of lipid turnover induced by Pi stress ENSG00000173599 PMC3226388__F3 Mammalian target of rapamycin complex 1 (mTORC1) signaling pathway ENSG00000198793 ENSG00000284161 PMC2844927__F3 Routes of interaction between epoxyeicosanoid and endocannabinoid signaling pathways ENSG00000117480 ENSG00000196689 PMC10536747__F2 Liver and Muscle Transcriptomes Differ in Mid-Lactation Cows Divergent in Feed Efficiency in the Presence or Absence of Supplemental Rumen-Protected Choline ENSG00000106617 ENSG00000134324 ENSG00000099194 ENSG00000159399 PMC8866688__F1 Hypoglycemia Impairs the Heat Shock Protein Response: A Risk for Heat Shock in Cattle? ENSG00000103266 ENSG00000184787 ENSG00000089022 PMC10525531__F7 High Hepcidin Levels Promote Abnormal Iron Metabolism and Ferroptosis in Chronic Atrophic Gastritis ENSG00000167468 ENSG00000168610 PMC10745682__F2 Potential association between the ER stress signaling pathway and obesity ENSG00000128272 ENSG00000144895 ENSG00000169047 ENSG00000100219 PMC2801237__F5 Proposed revised model of mammalian DNA damage response ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000112130 PMC3170087__F2 dsRNA sensors and plasmacytoid dendritic cells in host defense and autoimmunity ENSG00000111537 ENSG00000164342 PMC3381108__F2 Unfolded protein response (UPR) ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 ENSG00000164305 PMC84049__F9 Control of LHB gene expression by Egr-1, Ptx1, and SF-1 ENSG00000109163 PMC6423962__F1 Expanded cholesterol synthesis pathway diagram ENSG00000132196 ENSG00000116133 ENSG00000143815 ENSG00000172893 ENSG00000149809 ENSG00000109929 ENSG00000113161 ENSG00000104549 PMC6923311__F4 Homology-directed repair pathway determination and its favorable cell contexts PMC6923311__F1 DSB repair pathways.1017In the C-NHEJ pathway, DSB formation induces binding to broken ends by KU70/80 heterodimers that subsequently recruit the DNA damage response kinase (DDK) complex such as DNA-PKcs in mammals ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000138346 ENSG00000080345 ENSG00000145321 PMC6079365__F2 Cellular Stresses and Stress Responses in the Pathogenesis of Insulin Resistance ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000026103 PMC3353643__F6 Proposed model of WNK4 signaling pathway mediating NCC regulation in DCT ENSG00000126562 ENSG00000143867 ENSG00000060237 ENSG00000118515 ENSG00000080166 PMC8125460__F2 From Channels to Canonical Wnt Signaling: A Pathological Perspective ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC9232569__F7 Targeting signaling pathways in prostate cancer: mechanisms and clinical trials ENSG00000134982 ENSG00000185483 ENSG00000168036 ENSG00000108375 PMC5310573__F5 Estrogen metabolism pathway including enzymes (blue field) and chemical compounds ENSG00000086696 ENSG00000132196 ENSG00000108786 ENSG00000133835 ENSG00000203857 PMC4867368__F12 Comparison of the lipoate assembly pathways of E ENSG00000107798 ENSG00000173239 PMC8647428__F1 Osteochondroma Pathogenesis ENSG00000162552 ENSG00000170365 ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000134245 ENSG00000164690 ENSG00000177283 ENSG00000163501 PMC3412587__F1 Ras signaling pathway which is disrupted in juvenile myelomonocytic leukemia (JMML) ENSG00000171456 ENSG00000110395 ENSG00000115904 ENSG00000196712 PMC8047216__F1 Stem cell migration ENSG00000169248 ENSG00000186810 ENSG00000183625 ENSG00000121966 PMC6072433__F6 Acetaminophen-induced S-nitrosylation and S-sulfenylation signalling in 3D cultured hepatocarcinoma cell spheroids ENSG00000130649 ENSG00000168036 ENSG00000136770 PMC6072433__F4 APAP-sensitive proteins related to protein synthesis ENSG00000134970 ENSG00000116161 ENSG00000197958 ENSG00000113558 ENSG00000106263 ENSG00000142534 ENSG00000149273 ENSG00000111530 ENSG00000167658 ENSG00000168036 ENSG00000174444 PMC4981742__F1 Mitochondrial dysfunction in gliomas- Evasion of Apoptosis: Impaired mitochondrial function due to the genomic mutations in mtDNA leads to impaired function of electron transport chain thus enhancing generation of ROS ENSG00000138798 ENSG00000198793 ENSG00000120868 PMC11076710__F9 Nrf2/ARE signaling pathway, mitochondrial ROS, and NLRP3 inflammasome in renal tubular epithelial cells under high lipid conditions ENSG00000162711 ENSG00000181019 ENSG00000079999 PMC8272378__F2 Altered skeletal muscle metabolic pathways, age, systemic inflammation, and low cardiorespiratory fitness associate with improvements in disease activity following high-intensity interval training in persons with rheumatoid arthritis ENSG00000121897 ENSG00000160194 ENSG00000291958 ENSG00000176894 ENSG00000174748 ENSG00000005882 ENSG00000137992 ENSG00000105953 ENSG00000145020 ENSG00000091140 ENSG00000178445 ENSG00000101365 PMC7466429__F2 Signaling pathways activated by catecholamines ENSG00000136997 ENSG00000048028 ENSG00000168610 PMC7466429__F3 Stress hormones on the immune system ENSG00000134982 PMC7596389__F9 Schematic presentation probable protective mechanism of Ursodeoxycholic acid (UDCA) against As(III)-mediated hepatic injury by activating the Nrf2 pathway ENSG00000132906 ENSG00000116044 ENSG00000181019 ENSG00000171791 ENSG00000164294 ENSG00000164305 ENSG00000079999 PMC6116077__F3 Interferon pathway ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000115415 PMC2696566__F1 Synergistic combinations of signaling pathway inhibitors: Mechanisms for improved cancer therapy ENSG00000070831 ENSG00000291971 ENSG00000169047 ENSG00000198793 ENSG00000163914 ENSG00000081189 ENSG00000140443 PMC2696566__F2 Synergistic combinations of signaling pathway inhibitors: Mechanisms for improved cancer therapy ENSG00000143799 ENSG00000149311 ENSG00000175054 PMC10968558__F6 Oxidative Stress in Spinocerebellar Ataxia Type 3 and Its Attenuation by Herbal Remedies in Traditional Chinese Medicine: A Systematic Review ENSG00000109819 ENSG00000170899 ENSG00000284774 ENSG00000116044 ENSG00000181019 ENSG00000066427 ENSG00000101333 ENSG00000067715 PMC8389183__F5 Recent ecophysiological, biochemical and evolutional insights into plant carnivory ENSG00000151657 PMC5297839__F1 Phosphatidylinositol-3-kinase/mammalian target of rapamycin (PI3K/mTOR), retrovirus-associated DNA sequences/mitogen activated protein kinase (RAS/MAPK) pathways and c-MYC are master regulators of cell growth and proliferation ENSG00000101751 PMC10968558__F2 Mitochondrial dysfunction in the pathogenesis of SCA3 ENSG00000171791 ENSG00000066427 PMC8552808__F3 Treatment of COVID-19 with Traditional Chinese Medicine: What Herbs Can Help Win the Battle with SARS-CoV-2? ENSG00000134982 PMC10968558__F3 Alteration of DNA damage response in the pathogenesis of SCA3 ENSG00000149311 ENSG00000175054 ENSG00000039650 ENSG00000149554 PMC9288037__F1 Biomarker discovery for practice of precision medicine in hypopharyngeal cancer: a theranostic study on response prediction of the key therapeutic agents ENSG00000143799 ENSG00000160789 ENSG00000087245 ENSG00000152661 ENSG00000167757 ENSG00000101057 ENSG00000173039 ENSG00000188229 ENSG00000176014 ENSG00000178980 ENSG00000104833 ENSG00000171791 ENSG00000166263 ENSG00000132646 ENSG00000173599 ENSG00000136997 ENSG00000164362 ENSG00000123374 ENSG00000171840 ENSG00000146648 ENSG00000113448 PMC6854373__F8 Graphical abstract of how EGFR signaling pathway and downstream effector inhibit the miR-124a expression and the role of ETS2 in insulin production in pancreatic beta cells ENSG00000157557 ENSG00000139515 PMC2923715__F5 Wnt signaling pathways ENSG00000168036 ENSG00000113971 PMC8027424__F1 Autotrophic and mixotrophic metabolism of an anammox bacterium revealed by in vivo 13C and 2H metabolic network mapping ENSG00000197713 ENSG00000127948 ENSG00000062485 PMC7923692__F1 RPTOR BioID2 reveals spatial association between mTORC1 and FAs ENSG00000197043 ENSG00000044090 ENSG00000102606 ENSG00000169047 ENSG00000155792 ENSG00000108443 ENSG00000164327 ENSG00000167965 ENSG00000141564 ENSG00000101407 ENSG00000239732 ENSG00000106070 ENSG00000136997 ENSG00000135932 ENSG00000198933 ENSG00000119487 ENSG00000101639 ENSG00000143862 ENSG00000116586 ENSG00000196455 ENSG00000169756 ENSG00000204138 ENSG00000085415 ENSG00000149357 ENSG00000132356 ENSG00000143375 ENSG00000187840 ENSG00000204673 ENSG00000109270 ENSG00000175390 ENSG00000136205 ENSG00000291971 ENSG00000198793 ENSG00000121879 ENSG00000148484 ENSG00000118640 ENSG00000197702 ENSG00000089159 ENSG00000197256 ENSG00000168003 ENSG00000048707 ENSG00000165458 ENSG00000284099 ENSG00000198286 ENSG00000104365 ENSG00000197081 ENSG00000155876 ENSG00000069329 ENSG00000122786 ENSG00000085662 ENSG00000042753 ENSG00000025039 ENSG00000153317 ENSG00000173517 ENSG00000144791 ENSG00000148730 ENSG00000110719 ENSG00000065135 ENSG00000183020 ENSG00000137076 ENSG00000171608 ENSG00000143924 PMC3012004__F2 Sites of action for inhibitors and shRNAs in the EGFR-PI3K-Akt-mTOR pathway ENSG00000169047 ENSG00000198793 ENSG00000164327 ENSG00000146648 PMC8005514__F3 PI3K/AKT pathway and HER2-targeted therapy resistance ENSG00000198793 ENSG00000145113 ENSG00000140443 PMC8005514__F4 PI3K/AKT pathway is related to chemotherapy, CDK4/6 and PARP inhibitor resistance ENSG00000291971 ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000138385 ENSG00000079999 PMC8005514__F1 PI3K/AKT signaling pathway in breast cancer ENSG00000002330 PMC3012004__F1 PI3 kinase signaling pathway in glioma ENSG00000002330 ENSG00000198793 ENSG00000164327 ENSG00000146648 ENSG00000140443 PMC2928642__F8 The PA-mediated activation of mTORC1 signaling ENSG00000173599 ENSG00000198670 PMC10239497__F10 Dissecting specific Wnt components governing osteogenic differentiation potential by human periodontal ligament stem cells through interleukin-6 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000165879 ENSG00000168036 PMC6643108__F5 Relation graph of KEGG pathways in which differentially expressed genes were significantly enriched ENSG00000058085 ENSG00000050748 ENSG00000132646 ENSG00000026103 ENSG00000175305 PMC4241130__F2 Energy Metabolic Re-Programming in the Hypertrophied and Early Stage Failing Heart: A Multi-systems Approach ENSG00000117054 ENSG00000157766 PMC8503815__F2 Emerging role of BAD and DAD1 as potential targets and biomarkers in cancer ENSG00000132906 ENSG00000128272 ENSG00000002330 ENSG00000164305 PMC3877975__F5 Coordinately up-regulated genes of chemokine signaling pathway in monocytes from the VIR group (VIR versus BDL) ENSG00000169291 PMC5342747__F5 Polarization of macrophages in the tumor microenvironment is influenced by EGFR signaling within colon cancer cells ENSG00000138798 ENSG00000146648 ENSG00000140443 PMC8136775__F1 Untangling the crosstalk between BRCA1 and R-loops during DNA repair ENSG00000143799 ENSG00000083093 ENSG00000138346 ENSG00000197299 ENSG00000051180 ENSG00000139618 PMC3976145__F1 Genes involved in the WNT signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167074 PMC8156432__F8 Orai1 Channel Regulates Human-Activated Pancreatic Stellate Cell Proliferation and TGFB1 Secretion through the AKT Signaling Pathway ENSG00000105329 ENSG00000167323 ENSG00000293604 PMC3826118__F1 Role of Calcium, Vitamin D, and the Extrarenal Vitamin D Hydroxylases in carinogenesis ENSG00000019186 ENSG00000168036 ENSG00000036828 ENSG00000196628 PMC7916216__F2 Direct and indirect effects of radiotherapy, chemotherapy, and protein kinase inhibitors on NK cell activity ENSG00000131015 ENSG00000157764 ENSG00000161921 ENSG00000276051 ENSG00000204520 PMC7882494__F7 Pathway analysis ENSG00000121989 ENSG00000157764 ENSG00000065361 ENSG00000134982 ENSG00000168036 ENSG00000183765 ENSG00000149311 ENSG00000177189 ENSG00000136997 ENSG00000050165 ENSG00000104371 ENSG00000168646 ENSG00000140443 PMC8282181__F3 Protein Kinases: Potential Drug Targets Against Schistosoma japonicum ENSG00000110395 ENSG00000150907 ENSG00000198793 PMC8282181__F4 Protein Kinases: Potential Drug Targets Against Schistosoma japonicum ENSG00000070831 ENSG00000127191 PMC7669714__F3 DNA replication restart pathway choice ENSG00000004142 ENSG00000164306 ENSG00000130997 ENSG00000198056 ENSG00000122008 PMC10503159__F9 Proposed model depicting the possible mechanism of bta-miR-223 on mediating inflammatory injuries and oxidative stress via regulation of NLRP3 inflammasome and Keap1/Nrf2 pathway ENSG00000162711 ENSG00000136869 ENSG00000079999 PMC8122117__F4 Genetic predisposition similarities between NASH and ASH: Identification of new therapeutic targets ENSG00000198793 ENSG00000273592 PMC4272512__F2 Immune, antioxidant and inflammatory targets that L-glutamine, L-arginine and BCAA are involved ENSG00000284774 ENSG00000198793 ENSG00000096717 ENSG00000115419 ENSG00000007171 PMC3705552__F2 TIR8/SIGIRR, a negative regulatory receptor of ILR and TLR signaling ENSG00000198793 ENSG00000172936 ENSG00000185187 PMC6441003__F7 Proposed model for the impact of Metformin on FOXO3a and gene transcription in primary human fibroblasts ENSG00000115008 PMC12081257__F1 Protective factors against oxidative stress in COPD: focus on Nrf2-dependent antioxidant gene expression ENSG00000181019 ENSG00000023909 ENSG00000079999 PMC1186734__F6 Glucocorticoid Receptor-Dependent Gene Regulatory Networks ENSG00000282905 ENSG00000106004 ENSG00000169856 ENSG00000148926 ENSG00000170606 ENSG00000205250 ENSG00000164305 ENSG00000230034 ENSG00000168522 ENSG00000109819 ENSG00000157557 ENSG00000084676 ENSG00000136997 ENSG00000276051 ENSG00000146678 ENSG00000158874 ENSG00000100811 ENSG00000103266 ENSG00000137673 ENSG00000173039 ENSG00000273686 ENSG00000132170 ENSG00000180447 ENSG00000115415 ENSG00000177606 ENSG00000124253 ENSG00000127616 PMC8383365__F1 Pyroptosis at the forefront of anticancer immunity ENSG00000278718 ENSG00000162711 ENSG00000137275 ENSG00000163568 ENSG00000125538 ENSG00000163914 ENSG00000167914 ENSG00000091592 ENSG00000168040 ENSG00000147697 ENSG00000073605 PMC6833007__F1 Mechanisms involved in activation and regulation of NLRP3 canonical pathway ENSG00000172936 ENSG00000283100 PMC7166547__F2 Innate immune response and adaptive immune responses of Coronaviruses (CoV) infection during an infection ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000276561 ENSG00000164342 PMC7180609__F7 Glutamine-dependent metabolic pathways in T ENSG00000084110 ENSG00000100033 PMC6383680__F6 Nucleotide-binding oligomerization domain-containing protein (NOD)1 and NOD2 signaling cascades ENSG00000167207 ENSG00000082512 ENSG00000157625 ENSG00000132478 ENSG00000175104 ENSG00000145782 ENSG00000127191 ENSG00000106100 ENSG00000057663 PMC6734087__F2 Canonical transforming growth factor (TGF)B and noncanonical pathways in endothelial to mesenchymal transition (EndMT) ENSG00000137834 ENSG00000124216 ENSG00000122691 ENSG00000198793 ENSG00000019549 PMC6734087__F3 Diagrammatic representation of other pathways involved in endothelial to mesenchymal transition (EndMT) regulation ENSG00000124216 ENSG00000086991 PMC11520539__F3 Diagram illustrates the immune exchange pathway mediated by ADAR1, a dsRNA A-to-I editing transformation modulating enzyme ENSG00000160710 ENSG00000187772 ENSG00000292332 PMC5968182__F1 Hypothetical roles of linear and circular ANRIL lncRNA in regulating inflammation and cell survival in human vascular endothelial cells and potential drug targets ENSG00000100811 ENSG00000100029 PMC6023503__F2 IPA pathway analysis, in which specific genes emerged throughout our review, are shown in purple ENSG00000120963 ENSG00000197386 ENSG00000183718 PMC7268359__F6 Schematic diagram of the mechanism of soyasaponins’ regulation on TLR4 signaling pathway ENSG00000170458 ENSG00000125538 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC6005741__F1 The force is strong with this one: Metabolism (over)powers stem cell fate ENSG00000131473 ENSG00000205221 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC5834423__F1 MicroRNAs (miRNAs) targeting insulin signaling mediators ENSG00000150907 ENSG00000169047 PMC5019081__F3 Wnt signaling pathways regulate gene expression and cell movements ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000070831 ENSG00000134982 PMC3717758__F3 Structure–activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease ENSG00000142192 ENSG00000100083 PMC7880430__F2 Finding branched pathways in metabolic network via atom group tracking ENSG00000203710 ENSG00000117322 ENSG00000102977 PMC5344939__F1 Molecular mechanisms of PI3K-AKT-mTOR signaling cascade related neurodevelopmental diseases ENSG00000176165 PMC2679770__F3 Proposed saxitoxin biosynthetic pathway ENSG00000166278 PMC9466315__F4 Immune responses to Lassa virus ENSG00000174125 ENSG00000183735 ENSG00000088888 ENSG00000134982 ENSG00000172936 ENSG00000131323 ENSG00000150455 PMC3390254__F1 An emerging role of mTOR in lipid biosynthesis ENSG00000198793 ENSG00000118515 ENSG00000155792 ENSG00000167965 PMC4151049__F2 Biochemical Signaling of PD-1 on T Cells and Its Functional Implications ENSG00000213658 ENSG00000010810 PMC4859290__F7 Analysis of signaling pathways specific to base:apex comparison ENSG00000280831 ENSG00000182774 ENSG00000105193 ENSG00000117118 ENSG00000198793 ENSG00000197728 ENSG00000177954 ENSG00000292058 ENSG00000070756 ENSG00000163435 ENSG00000164405 ENSG00000131174 ENSG00000102034 ENSG00000149273 PMC8278124__F8 Astragalus polysaccharide attenuates LPS‐related inflammatory osteolysis by suppressing osteoclastogenesis by reducing the MAPK signalling pathway ENSG00000136869 ENSG00000175104 ENSG00000127191 ENSG00000131196 ENSG00000143387 PMC9155915__F7 Pharmacological Mechanism of Shen Huang Chong Ji for Treating Alzheimer's Disease Based on Network Pharmacology and Experimental Validation ENSG00000177455 ENSG00000002330 ENSG00000069482 ENSG00000179091 ENSG00000186716 ENSG00000198793 PMC6822174__F1 Cell metabolism ENSG00000131473 ENSG00000169710 ENSG00000115419 PMC5343902__F2 Mammalian target of rapamycin (mTOR) pathway ENSG00000177169 ENSG00000138798 ENSG00000146648 PMC5451429__F8 Proposed model for the effects of GSK3B inhibitors on HCV virion particles’ assembly/release PMC8914022__F1 Weighing in on Adipogenesis ENSG00000078070 ENSG00000089163 ENSG00000128928 ENSG00000115419 PMC3823580__F8 Synergistic Effect of Everolimus and Chloroquine on Endothelial Cell Number Reduction Is Paralleled by Increased Apoptosis and Reduced Autophagy Occurrence ENSG00000198793 ENSG00000171791 ENSG00000105205 PMC3992201__F2 Genes identified in GWAS of Phase 1+2 AA subjects using a case-control model in the canonical pathway “calcium signaling.” The gene or gene families with a significant association result are shown in orange ENSG00000084774 PMC2702844__F2 Cell biology of autophagy in metazoans: a developing story ENSG00000171791 PMC8656925__F1 Targeted Therapy in HR+ HER2− Metastatic Breast Cancer: Current Clinical Trials and Their Implications for CDK4/6 Inhibitor Therapy and beyond Treatment Options ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC9688771__F2 Sweet Warning: Mucin-Type O-Glycans in Cancer ENSG00000069482 ENSG00000107862 ENSG00000291971 PMC9192598__F2 Integrative analysis to explore the biological association between environmental skin diseases and ambient particulate matter ENSG00000023445 ENSG00000003436 ENSG00000117228 ENSG00000101109 ENSG00000163739 ENSG00000163220 ENSG00000163565 ENSG00000164171 ENSG00000167772 ENSG00000100473 ENSG00000125398 ENSG00000186340 ENSG00000177606 ENSG00000100985 PMC9192598__F3 Integrative analysis to explore the biological association between environmental skin diseases and ambient particulate matter ENSG00000148346 ENSG00000186395 ENSG00000197632 ENSG00000140465 ENSG00000150782 ENSG00000041982 ENSG00000011422 ENSG00000163235 ENSG00000124882 ENSG00000177606 ENSG00000164400 ENSG00000128342 ENSG00000100985 ENSG00000162892 ENSG00000136689 PMC7052851__F1 Cholesterol biosynthesis pathway in cancer cells ENSG00000113161 ENSG00000104549 ENSG00000120437 ENSG00000075239 PMC3278830__F3 Functions related to hepatic cultures.Subgraphs of a hepatocyte response network induced by genes annotated with MSigDB gene sets ENSG00000070087 ENSG00000130649 ENSG00000008394 ENSG00000091409 ENSG00000173610 ENSG00000076003 ENSG00000230034 ENSG00000213949 ENSG00000196344 ENSG00000176248 ENSG00000130402 ENSG00000149554 ENSG00000133818 PMC7235470__F1 Cytokine storm and stress can increase gut dysbiosis/permeability, further contributing to cytokine induced IDO and TDO, leading to kynurenine and kynurenic acid, which activate the AhR to increase CYP1B1 and regulate the NAS/Melatonin ratio ENSG00000165841 ENSG00000106546 PMC9181382__F4 Rethinking Sesquiterpenoids: A Widespread Hormone in Animals ENSG00000110921 ENSG00000113161 PMC9373414__F1 CHAMP-study: the CHemopreventive effect of lithium in familial AdenoMatous Polyposis; study protocol of a phase II trial ENSG00000156076 ENSG00000134982 ENSG00000155011 ENSG00000185269 PMC1088000__F4 In Silico Analysis of the L ENSG00000198734 PMC3131135__F1 Viral myocarditis: potential defense mechanisms within the cardiomyocyte against virus infection ENSG00000239732 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC3131135__F2 Viral myocarditis: potential defense mechanisms within the cardiomyocyte against virus infection ENSG00000088888 PMC7919196__F2 Pathogenesis of COVID-19, showing the involvement of components of the fibrinolytic system in various steps ENSG00000130234 ENSG00000184012 ENSG00000122194 PMC3540170__F4 Immunoregulatory role of anchored cAMP signaling in T cells ENSG00000170458 ENSG00000136869 ENSG00000049768 PMC3975429__F1 MAPK signalling cascades leading to MK5 activation ENSG00000149269 PMC5224989__F3 Dietary Chromium Restriction of Pregnant Mice Changes the Methylation Status of Hepatic Genes Involved with Insulin Signaling in Adult Male Offspring ENSG00000171105 ENSG00000002330 ENSG00000198793 ENSG00000026103 PMC5655190__F14 Sodium fluoride induces renal inflammatory responses by activating NFKB signaling pathway and reducing anti-inflammatory cytokine expression in mice ENSG00000125538 ENSG00000113520 PMC9635866__F6 Realgar-induced KRAS mutation lung cancer cell death via KRAS/Raf/MAPK mediates ferroptosis ENSG00000167468 PMC7862443__F2 Met1-Ub Machinery ENSG00000083799 ENSG00000154124 PMC7724447__F1 Role of statins and PCSK9 inhibitors in COVID-19 pathophysiology and complications ENSG00000130164 ENSG00000130234 ENSG00000172936 ENSG00000169174 PMC5562164__F3 Innate Immunity to Intracellular pathogens: balancing microbial elimination and inflammation ENSG00000177169 ENSG00000069482 ENSG00000187608 PMC3877903__F9 Fumigaclavine C-induced apoptosis in MCF-7 breast cancer cells through the mitochondrial pathway ENSG00000002330 ENSG00000134057 ENSG00000123374 ENSG00000171791 PMC3996160__F6 A hypothetical model depicting the mechanisms used by SARS-CoV PLpro-TM to disrupt the STING-TRAF3-TBK1 complex required for activation of the IFNB production pathway ENSG00000183735 ENSG00000088888 ENSG00000131323 PMC5841288__F9 Model of the Itch/Beta-arrestin2-dependent regulation of the SuFu/Gli3 complex function ENSG00000106571 ENSG00000078747 ENSG00000164690 ENSG00000198125 ENSG00000128602 PMC6217971__F3 Co-occurrence networks of diagnostic KOs involved in major energy and carbon fixation metabolic pathways in Llamara microbial mats from pond LLA9 ENSG00000143252 ENSG00000073578 ENSG00000117118 ENSG00000166260 ENSG00000023697 ENSG00000155438 ENSG00000091140 PMC5853495__F7 Model for biosynthesis of sterols and other isoprenoids in rice roots ENSG00000112977 ENSG00000197429 ENSG00000198670 PMC6104109__F2 Canonical pathways of oxidative phosphorylation and mitochondrial dysfunction ENSG00000112695 ENSG00000110717 PMC1798432__F8 Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages ENSG00000111537 ENSG00000136869 PMC11006482__F9 Antagomir of miR-31-5p modulates macrophage polarization via the AMPK/SIRT1/NLRP3 signaling pathway to protect against DSS-induced colitis in mice ENSG00000162711 ENSG00000138029 ENSG00000096717 PMC5311241__F9 A positive feedback loop from Snail to Cat L to CUX1 and back to Snail drives EMT and can be inhibited by Cat L inhibitor PMC4484807__F6 Immunological Response to Single Pathogen Challenge with Agents of the Bovine Respiratory Disease Complex: An RNA-Sequence Analysis of the Bronchial Lymph Node Transcriptome ENSG00000239732 ENSG00000144410 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000143387 PMC4654299__F2 Regulation of endosomal trafficking ENSG00000041353 ENSG00000143761 ENSG00000165527 ENSG00000276600 ENSG00000124209 PMC7911386__F2 Signaling pathways of obese/T2D cell, of critical COVID-19 cases ENSG00000162711 ENSG00000108691 ENSG00000130234 ENSG00000125538 ENSG00000134070 ENSG00000172936 ENSG00000132693 ENSG00000276561 PMC4055129__F1 Inhibition mechanism of MTX in DNA synthesis pathway ENSG00000228716 ENSG00000136877 ENSG00000124275 PMC8584169__F2 Glutamate and GABA in Microglia-Neuron Cross-Talk in Alzheimer’s Disease ENSG00000168329 PMC6967775__F1 Synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC7843454__F3 Peroxisomal and mitochondrial fatty acid oxidation are dysregulated in both early and late CKD ENSG00000291507 ENSG00000122971 ENSG00000105379 PMC6682659__F3 Molecular consequences of the PrPC/AB interaction in AD ENSG00000010810 ENSG00000281879 PMC7599912__F3 Metabolic Pi sensing in mammals (modified from ) ENSG00000036828 ENSG00000176095 ENSG00000134548 PMC12116377__F2 Summary diagram illustrating PD-L1-related immune sensitivity and resistance mechanisms in GC ENSG00000145321 ENSG00000158104 ENSG00000026508 ENSG00000049768 PMC7028128__F8 Proposed model linking the miR‐574‐5p locus to the biology of goat mammary epithelial cells (GMECs) ENSG00000117020 ENSG00000002330 ENSG00000070831 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000065559 ENSG00000169032 ENSG00000146648 PMC8718268__F4 Dynamics of Wnt signalling ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000133067 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC8453690__F2 Electromagnetic Field as a Treatment for Cerebral Ischemic Stroke ENSG00000002330 ENSG00000100985 PMC6713433__F6 mRNA-miRNA-pathway regulatory network ENSG00000288263 ENSG00000113302 PMC8835409__F5 Estrogen Receptors-Mediated Apoptosis in Hormone-Dependent Cancers ENSG00000187325 PMC2964873__F1 The Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities ENSG00000144485 ENSG00000125398 ENSG00000181788 ENSG00000152952 PMC3848785__F3 Schematic diagram of the known PtdEtn biosynthetic pathways ENSG00000146005 PMC6769509__F3 Flavonoids as anti-diabetic agents: Modes of Action ENSG00000112715 PMC8388033__F4 Multi-layered network-based pathway activity inference using directed random walks: application to predicting clinical outcomes in urologic cancer ENSG00000094880 ENSG00000105329 ENSG00000087008 ENSG00000198691 ENSG00000069431 ENSG00000068976 ENSG00000117528 ENSG00000100504 ENSG00000139626 ENSG00000026103 ENSG00000143921 ENSG00000172380 ENSG00000161905 ENSG00000110107 ENSG00000100994 ENSG00000084110 ENSG00000143933 ENSG00000143578 ENSG00000179344 ENSG00000160224 ENSG00000127415 ENSG00000149485 ENSG00000127588 ENSG00000099804 ENSG00000164695 ENSG00000122971 ENSG00000186469 PMC8874859__F4 How RSV Proteins Join Forces to Overcome the Host Innate Immune Response ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000135114 ENSG00000185745 ENSG00000142089 ENSG00000131323 ENSG00000121060 ENSG00000276561 PMC6479799__F2 Mechanism of CB-R-mediated antitumor activity in breast cancer cells ENSG00000291971 ENSG00000130522 ENSG00000198793 ENSG00000168036 PMC7294576__F9 Beta-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NFKB Signaling Pathways ENSG00000170558 ENSG00000026508 PMC2966480__F4 E3 ubiquitin ligase activities of KEAP1 and AHR ENSG00000100387 ENSG00000106546 ENSG00000079999 PMC5504455__F10 Diagrammatic summary of the principal ways by which the Unfolded Protein Response pathway may interact with the mTOR/AKT pathway to modulate protein synthesis within the placenta ENSG00000144895 ENSG00000198793 ENSG00000167658 PMC3488210__F3 Sub-network found among the genes in a differential expression experiment that compares FA patients to controls ENSG00000157554 ENSG00000002330 ENSG00000134982 ENSG00000141279 ENSG00000198793 PMC3488210__F5 Significant sub-networks (see also ) found among the lists of most essential genes, ranked by the RIGER parameter, obtained for both cell lines: (A) Jurkat and (B) K562 ENSG00000104856 ENSG00000149311 ENSG00000076924 ENSG00000136997 ENSG00000163159 ENSG00000147604 ENSG00000173039 ENSG00000171863 ENSG00000131844 ENSG00000127337 ENSG00000145220 PMC5776165__F1 MAPK signaling pathway, where each MAPK phosphorylates several transcriptional factors, regulating protein expression ENSG00000136997 ENSG00000291761 ENSG00000081189 PMC3170087__F4 dsRNA sensors and plasmacytoid dendritic cells in host defense and autoimmunity ENSG00000131323 ENSG00000168040 PMC4060077__F1 Molecular switching from apoptosis to necroptosis ENSG00000168040 ENSG00000168404 ENSG00000247077 PMC5937214__F7 Signaling pathways between palmitate and TNFA for CCL2 production ENSG00000108691 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC5393155__F10 Insulin receptor signaling pathways ENSG00000102034 ENSG00000169047 ENSG00000198793 PMC8577797__F6 Shikonin suppresses colon cancer cell growth and exerts synergistic effects by regulating ADAM17 and the IL-6/STAT3 signaling pathway ENSG00000129667 ENSG00000144895 ENSG00000138798 ENSG00000179364 ENSG00000168610 ENSG00000146648 PMC3769702__F5 Pathway diagram of the CTLA4 signaling in cytotoxic T lymphocytes from the IPA ENSG00000213658 ENSG00000010810 ENSG00000163599 ENSG00000124181 PMC3172806__F7 A model of pericyte-induced EC survival signaling ENSG00000112715 PMC6121264__F6 Putative targets of down-regulated miRNAs in SHH MB CSC enriched pathways, include (A) pathways in cancer and (B) PI3K-Akt pathway ENSG00000044115 ENSG00000136997 ENSG00000168036 ENSG00000146648 PMC9502483__F2 Glial Cell-Mediated Neuroinflammation in Alzheimer’s Disease ENSG00000162711 ENSG00000135218 ENSG00000073060 ENSG00000136869 ENSG00000100985 PMC4687464__F2 Wilms' tumor 1 (WT1) contributes to metanephric mesenchyme self-renewal and its differentiation ENSG00000128713 ENSG00000162552 ENSG00000103449 ENSG00000180447 ENSG00000075891 ENSG00000276799 ENSG00000164619 PMC7465315__F1 Keratinization at a glance ENSG00000125780 ENSG00000285348 PMC5354742__F3 Gene expression profiling of tumor-initiating stem cells from mouse Krebs-2 carcinoma using a novel marker of poorly differentiated cells ENSG00000175206 ENSG00000087245 ENSG00000161905 ENSG00000141448 ENSG00000262635 ENSG00000091972 ENSG00000288174 ENSG00000163737 ENSG00000178796 ENSG00000078596 ENSG00000005421 ENSG00000163421 ENSG00000132326 ENSG00000077782 ENSG00000113448 ENSG00000171408 PMC6815045__F3 PI3K-Akt signaling pathway ENSG00000177455 ENSG00000132906 ENSG00000103479 ENSG00000164879 ENSG00000065833 ENSG00000033327 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000213445 ENSG00000136997 PMC7700122__F2 Under normal homeostatic conditions, Keap1 homodimerizes through the N-terminal BTB domain and binds to the cullin-based (Cul3) E3 ligase, forming Keap1-Cul3-RBX1 (Ring box protein-1) E3 ligase complex, leading to Nrf2 ubiquitination and degradation ENSG00000181019 ENSG00000100387 ENSG00000023909 ENSG00000079999 PMC9672378__F1 Myeloid and lymphoid cell development by O-glycans on Notch ENSG00000283780 ENSG00000128917 ENSG00000148400 ENSG00000138798 ENSG00000137845 PMC10035973__F6 RNA-seq and microRNA association analysis to explore the pathogenic mechanism of DHAV-1 infection with DEHs ENSG00000099968 ENSG00000116688 ENSG00000131323 PMC8624316__F1 Aberrant DNA Methylation Mediates the Transgenerational Risk of Metabolic and Chronic Disease Due to Maternal Obesity and Overnutrition ENSG00000088305 ENSG00000139372 PMC7423897__F3 Overlap of identified miRNA targets with pathways related to the pathogenesis of atherosclerosis ENSG00000183625 ENSG00000006327 ENSG00000121807 ENSG00000273936 ENSG00000121966 PMC9679015__F2 Polymerase D-interacting protein family and their emerging roles in diseases ENSG00000144182 ENSG00000166855 ENSG00000114346 ENSG00000004142 ENSG00000170558 ENSG00000086991 ENSG00000196689 PMC5090832__F1 JAK/STAT, Raf/MEK/ERK, and PI3K/PTEN/Akt/mTOR pathway cascades.In the JAK/STAT pathway, JAK2, which can be inhibited by AG490 and/or SOCS3, can phosphorylate STAT3 through downstream signalling ENSG00000198793 ENSG00000168610 PMC5090832__F2 Proposed signaling mechanism underlying the neuroprotective role of tPA.tPA enters the cell where it indirectly activates cellular signaling mechanisms, including Janus kinase 2 (JAK2) and/or mammalian target of rapamycin (mTOR) ENSG00000198793 ENSG00000168610 PMC7922220__F2 GnRH-II signaling in ovarian cancer cells assuming that a truncated GnRH-II receptor (A) or no GnRH-II receptor (B) exists ENSG00000130522 ENSG00000138798 ENSG00000146648 PMC7599984__F1 Wnt signaling pathway ENSG00000281324 ENSG00000162337 PMC11206395__F3 Therapeutic mechanism of polyphenols for anxiety disorder PMC7922220__F1 GnRH-I receptor signaling in ovarian cancer cells ENSG00000291971 ENSG00000130522 ENSG00000138798 ENSG00000146648 PMC7599984__F3 TGFB family signaling pathway ENSG00000170365 PMC7599984__F4 Hedgehog signaling pathway ENSG00000144857 ENSG00000128602 PMC6503366__F5 “Cytokine–cytokine receptor interaction”, “steroid biosynthesis” and “cell cycle” pathway and the identified regulator ENSG00000104899 ENSG00000138798 ENSG00000187266 ENSG00000145386 ENSG00000112715 ENSG00000170365 ENSG00000115415 ENSG00000134057 ENSG00000116133 ENSG00000132646 ENSG00000123374 ENSG00000146648 ENSG00000113494 PMC3362297__F11 Proposed roles of the calcineurin signaling cascade in stress responses, drug tolerance, and virulence in C ENSG00000101871 ENSG00000117906 PMC10242157__F7 Versatile role of Serpina3c in physiological and pathological processes: a review of recent studies ENSG00000074800 ENSG00000150907 ENSG00000168036 ENSG00000136869 PMC7823885__F3 Pathways of lipid metabolism modulation in hepatic tissue by the Gl-2 extract of a Mexican strain of Ganoderma lucidum, under a high-cholesterol diet (HCD) given to C57BL/6 mice ENSG00000170608 ENSG00000131473 ENSG00000160752 ENSG00000065833 ENSG00000142178 ENSG00000159388 ENSG00000177606 ENSG00000122877 ENSG00000169710 ENSG00000162772 ENSG00000079931 PMC6147049__F3 ER signaling pathway PMC6147049__F4 HER2 signaling pathway ENSG00000198793 PMC6147049__F5 Canonical Wnt/Beta-catenin signaling pathway ENSG00000137673 ENSG00000134982 ENSG00000026508 PMC2933905__F2 Distinct functions for TPPII in the nucleus and cytosol ENSG00000149311 ENSG00000138385 PMC11978336__F5 Interaction between lipid metabolism and macrophage polarization in atherosclerosis ENSG00000162711 ENSG00000136869 ENSG00000160179 PMC12170582__F5 This figure illustrates the diverse neuroprotective effects of Rut and its underlying molecular mechanisms ENSG00000164879 ENSG00000142192 ENSG00000136869 PMC9349561__F5 Exploration of molecular targets and mechanisms of Chinese medicinal formula Acacia Catechu ‐Scutellariae Radix in the treatment of COVID‐19 by a systems pharmacology strategy ENSG00000110711 ENSG00000002330 ENSG00000167207 ENSG00000140263 ENSG00000105656 ENSG00000007908 ENSG00000166278 ENSG00000127191 ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000006712 ENSG00000157227 ENSG00000078747 ENSG00000170571 PMC12170582__F3 This figure reveals important factors in anti-inflammatory signaling pathway of Rut in the CNS microenvironment ENSG00000162711 ENSG00000136869 ENSG00000118520 PMC1201250__F7 Mechanism of TgHSP70 tolerance in PMs from WT mice ENSG00000042832 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC7847688__F3 Roles of Pin1 in virus infection ENSG00000127445 ENSG00000168036 ENSG00000168610 PMC6781638__F4 Pathway analysis shows the identified proteins and their respective interactions ENSG00000134982 ENSG00000166136 ENSG00000139180 ENSG00000164405 ENSG00000184752 ENSG00000110717 ENSG00000142192 ENSG00000264522 ENSG00000127955 ENSG00000070366 ENSG00000004779 ENSG00000102468 ENSG00000165264 ENSG00000178127 ENSG00000267855 ENSG00000047579 ENSG00000108179 ENSG00000127184 ENSG00000131174 ENSG00000213619 ENSG00000204120 ENSG00000184076 ENSG00000189043 ENSG00000292254 ENSG00000140740 ENSG00000073578 ENSG00000133687 ENSG00000164305 ENSG00000149295 ENSG00000115317 ENSG00000147123 ENSG00000276825 ENSG00000184845 ENSG00000132388 ENSG00000120868 ENSG00000132906 ENSG00000169021 ENSG00000147684 ENSG00000184983 ENSG00000120705 ENSG00000078668 ENSG00000126267 ENSG00000076706 ENSG00000165059 ENSG00000065135 ENSG00000065609 ENSG00000040608 ENSG00000143252 ENSG00000291606 ENSG00000186010 ENSG00000099795 ENSG00000064692 ENSG00000119013 ENSG00000182179 ENSG00000188641 ENSG00000118007 ENSG00000130414 ENSG00000144619 ENSG00000106688 ENSG00000100346 ENSG00000196628 ENSG00000170775 ENSG00000156587 ENSG00000165646 ENSG00000184304 ENSG00000160194 ENSG00000185633 ENSG00000158828 ENSG00000117152 ENSG00000292058 ENSG00000010256 ENSG00000183648 ENSG00000127540 ENSG00000109390 ENSG00000277018 ENSG00000065518 ENSG00000151366 ENSG00000100336 ENSG00000109572 ENSG00000175899 ENSG00000128335 ENSG00000198597 ENSG00000135018 ENSG00000036565 ENSG00000154146 ENSG00000170396 ENSG00000160471 ENSG00000135999 ENSG00000116176 ENSG00000131495 ENSG00000166886 ENSG00000185651 ENSG00000124212 ENSG00000182511 ENSG00000142599 ENSG00000137843 ENSG00000099904 ENSG00000110497 ENSG00000198833 ENSG00000179091 ENSG00000160087 ENSG00000156467 ENSG00000281123 ENSG00000184787 ENSG00000120910 ENSG00000002822 ENSG00000135250 PMC5974360__F10 Wnt/Beta-catenin and hedgehog signaling in myofibroblast differentiation ENSG00000188064 ENSG00000168036 PMC2885761__F2 Schematical overview of the signaling pathway mediated by MC1R PMC6678287__F6 Simplified pathways showing the effect of F-6 cell proliferation and death ENSG00000132906 ENSG00000198793 ENSG00000164305 PMC4699037__F1 Signaling affecting stem cells identity and their interplay with chromatin ENSG00000156574 ENSG00000128342 ENSG00000168610 ENSG00000136826 PMC11978336__F2 Interaction between lipid metabolism and macrophage polarization in atherosclerosis ENSG00000138075 ENSG00000167910 ENSG00000132693 ENSG00000143921 PMC11978336__F3 Interaction between lipid metabolism and macrophage polarization in atherosclerosis ENSG00000162692 ENSG00000213523 PMC6121264__F5 Putative targets of up-regulated miRNAs in SHH MB CSC enriched pathways, include (A) pathways in cancer, (B) PI3K-Akt pathway, and (C) protein processing in endoplasmic reticulum ENSG00000130939 ENSG00000168209 ENSG00000172380 ENSG00000182446 ENSG00000159461 ENSG00000150093 ENSG00000165280 ENSG00000140943 ENSG00000127022 ENSG00000105647 ENSG00000213341 ENSG00000105568 ENSG00000163479 ENSG00000076604 ENSG00000152700 ENSG00000114850 ENSG00000058262 ENSG00000113558 ENSG00000135018 ENSG00000077782 ENSG00000090520 ENSG00000089597 PMC11978336__F1 Interaction between lipid metabolism and macrophage polarization in atherosclerosis ENSG00000173599 ENSG00000198670 PMC3575576__F6 Proposed signaling pathway ENSG00000122691 PMC4377308__F3 Genetic alterations of protein tyrosine phosphatases in human cancers ENSG00000196090 ENSG00000291971 ENSG00000168610 ENSG00000084774 ENSG00000179295 PMC2908016__F2 Therapeutic HPV vaccines PMC6627937__F7 Graphical illustration of the proposed mode of FBXW5-induced regulation of intracellular signaling in gastric cancer ENSG00000159069 ENSG00000070831 ENSG00000291971 ENSG00000067900 PMC2708714__F2 Direct targets of WT1 identified in the Wnt signaling pathway ENSG00000087095 ENSG00000101849 ENSG00000134982 ENSG00000168036 ENSG00000165617 PMC6347501__F3 ‘Stemness’ maintenance pathways in CSCs ENSG00000067992 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000005882 ENSG00000168036 ENSG00000167074 ENSG00000128602 ENSG00000118777 PMC8394908__F3 Splicing factor mutations in hematologic malignancies ENSG00000162385 ENSG00000105722 ENSG00000136807 ENSG00000151461 ENSG00000125351 ENSG00000146834 PMC8949786__F5 Characterization of Accessible Chromatin Regions in Cattle Rumen Epithelial Tissue during Weaning ENSG00000123999 ENSG00000170365 ENSG00000137834 ENSG00000006451 ENSG00000163083 ENSG00000188130 ENSG00000171791 ENSG00000135341 ENSG00000102935 ENSG00000133818 PMC8949786__F6 Characterization of Accessible Chromatin Regions in Cattle Rumen Epithelial Tissue during Weaning ENSG00000111057 ENSG00000162458 ENSG00000140983 ENSG00000221914 ENSG00000168036 ENSG00000150093 ENSG00000164327 ENSG00000105647 ENSG00000197702 ENSG00000077150 ENSG00000169750 ENSG00000136997 ENSG00000071051 ENSG00000130402 ENSG00000136068 ENSG00000138795 ENSG00000196455 ENSG00000100345 ENSG00000115221 ENSG00000284984 ENSG00000128272 ENSG00000146592 ENSG00000072110 ENSG00000092841 ENSG00000188130 ENSG00000150630 PMC3148591__F2 Major signaling pathways of IPC- and Ipost-mediated protection against cardiac cell death ENSG00000168610 PMC8204759__F1 Golgi-localised components that mediate mechanistic (or mammalian) target of rapamycin complex 1 (mTORC1) signalling ENSG00000113384 ENSG00000143761 PMC3204848__F13 Glucose and collagen regulate human platelet activity through aldose reductase induction of thromboxane ENSG00000197943 PMC6470053__F8 Nature and nurture: Confluence of pathway determinism with metabolic and chemical serendipity diversifies Monascus azaphilone pigments ENSG00000124575 ENSG00000124610 ENSG00000184357 PMC3341711__F1 TGFB/Smad canonical signaling pathway PMC6470053__F9 Nature and nurture: Confluence of pathway determinism with metabolic and chemical serendipity diversifies Monascus azaphilone pigments ENSG00000124610 ENSG00000184357 PMC9485288__F8 G3BP2 regulates oscillatory shear stress-induced endothelial dysfunction ENSG00000138757 ENSG00000162692 PMC8832959__F1 Cancer metabolism and dietary interventions ENSG00000125166 ENSG00000131473 ENSG00000065833 ENSG00000122966 ENSG00000060982 ENSG00000138030 ENSG00000172005 ENSG00000075239 ENSG00000105552 ENSG00000159399 PMC6001654__F1 Role of DKK4 in different signal pathway ENSG00000104371 ENSG00000026508 ENSG00000168036 PMC8096907__F2 miRNAs Alter T Helper 17 Cell Fate in the Pathogenesis of Autoimmune Diseases ENSG00000162594 ENSG00000137265 ENSG00000103522 ENSG00000168610 PMC7845572__F2 An overview of cellular metabolic pathways in MM cells ENSG00000159399 PMC7879452__F6 In nucleus, Lnc-BTG3-7:1 co-regulates the transcription of C21ORF91 gene with nuclear synergistic transcription factor JUND ENSG00000154642 ENSG00000130522 ENSG00000168036 PMC8002431__F4 Gene networks regulating flowering time showing differentially expressed genes in cid3cid4 ENSG00000163435 ENSG00000102034 ENSG00000140598 ENSG00000203783 ENSG00000186654 ENSG00000131188 PMC8311559__F1 Alterations in and the Role of the Th17/Treg Balance in Metabolic Diseases ENSG00000134982 ENSG00000125538 ENSG00000198793 ENSG00000049768 ENSG00000168610 PMC6944118__F8 Working model of the role of HERC2 in p53‐MDM2 loop regulation ENSG00000149311 ENSG00000175054 ENSG00000288301 PMC3742228__F2 Schematic overview of Hedgehog signaling and rationale for combination therapy with (chemo)radiotherapy ENSG00000149311 ENSG00000106571 ENSG00000173599 ENSG00000168036 ENSG00000164690 ENSG00000100985 ENSG00000128602 ENSG00000118777 PMC7226770__F3 Blood–brain barrier, theoretically a motorway for a melting-pot of EXOs ENSG00000041353 ENSG00000117335 PMC2770887__F1 ER stress-induced signaling pathways that mediate autophagy ENSG00000143486 ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC4110175__F5 LDN Inhibition in TGFB Signaling Pathway adapted from KEGG 04350 ENSG00000170365 ENSG00000111537 ENSG00000095739 ENSG00000100387 ENSG00000113558 PMC5047918__F2 Simplified view of B ENSG00000150787 PMC4110175__F2 SP600125 and BCI Inhibition in MAPK Signaling Pathway adapted from KEGG 04010 ENSG00000146648 PMC8604912__F7 Molecular mechanism by which Lactobacillus spp. regulate the core fucosylation of epithelial cellsthrough the Wnt pathway ENSG00000168036 ENSG00000277641 PMC8353313__F6 Coeloglossum viride var. bracteatum extract attenuates staurosporine induced neurotoxicity by restoring the FGF2-PI3K/Akt signaling axis and Dnmt3 ENSG00000088305 ENSG00000164305 PMC4444401__F6 Function of the Chondrocyte PI-3 Kinase-Akt Signaling Pathway is Stimulus Dependent ENSG00000145623 ENSG00000099985 ENSG00000125538 ENSG00000169047 ENSG00000168610 ENSG00000115594 PMC9117016__F9 Wheel-Running Exercise Protects Ovariectomized Mice from Bone Loss via IFN-Gamma-Mediated Suppression of the NFKB and MAPK Pathways ENSG00000175104 ENSG00000131196 ENSG00000143387 PMC9185832__F1 Cancer pharmacomicrobiomics: targeting microbiota to optimise cancer therapy outcomes ENSG00000150782 ENSG00000111537 ENSG00000172936 PMC7947359__F2 BPs in the macrophage polarization ENSG00000162711 ENSG00000115415 PMC7195796__F6 Effect of P17 reovirus on cancerous signaling pathway ENSG00000047410 ENSG00000123374 ENSG00000105810 PMC4100983__F4 Vemurafenib and panitumumab combination tailored therapy in BRAF-mutated metastatic colorectal cancer ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC4859317__F1 Current concepts regarding developmental mechanisms in diabetic retinopathy in Taiwan ENSG00000198793 PMC4440397__F1 Calcium channels in T cells ENSG00000167323 ENSG00000134982 ENSG00000124181 PMC4678629__F2 Classical pathways of type I IFN induction and HCV mediating IFN resistance ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000164342 PMC9496732__F3 Regulating the Expression of HIF-1A or lncRNA: Potential Directions for Cancer Therapy ENSG00000170558 PMC10990278__F1 The Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000102312 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC8438241__F7 Sec62 Regulates Endoplasmic Reticulum Stress and Autophagy Balance to Affect Foot-and-Mouth Disease Virus Replication ENSG00000198382 ENSG00000008952 ENSG00000100219 PMC6708269__F1 Metabolism and Redox in Pulmonary Vascular Physiology and Pathophysiology ENSG00000105227 PMC5745708__F9 PMSC differentiation into skeletal muscle using the insulin-like growth factor system ENSG00000122180 ENSG00000167779 ENSG00000169047 ENSG00000198793 PMC7408912__F4 Scheme presenting the major proteins of the DNA damage response (DDR) signaling pathway and the miRNAs that interact with them ENSG00000188486 ENSG00000149311 PMC7408912__F5 MiRNA regulation of homologous recombination (HR) repair factors after IR ENSG00000188486 ENSG00000149311 ENSG00000083093 ENSG00000051180 ENSG00000139618 PMC3904625__F8 Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation ENSG00000151702 ENSG00000159216 ENSG00000107890 PMC8232085__F4 Polyphenol Supplementation Reverses Age-Related Changes in Microglial Signaling Cascades ENSG00000143799 ENSG00000147649 ENSG00000213614 ENSG00000172009 ENSG00000170606 ENSG00000168036 ENSG00000169710 ENSG00000244731 ENSG00000126261 ENSG00000236625 ENSG00000163631 ENSG00000173369 ENSG00000125538 ENSG00000108821 ENSG00000275565 ENSG00000143546 ENSG00000169896 ENSG00000101160 ENSG00000133835 ENSG00000119596 ENSG00000085662 ENSG00000274442 ENSG00000110719 ENSG00000281614 ENSG00000111537 ENSG00000115415 ENSG00000184270 ENSG00000163131 ENSG00000167986 ENSG00000155660 ENSG00000167996 ENSG00000132341 PMC5823630__F6 Anti-estrogens mitigate mTORC1 inhibitor-induced activation of PI3K/AKT ENSG00000171105 ENSG00000169047 ENSG00000140443 PMC4390903__F2 DNA damage pathways and how CHK1-, WEE1-, or CDK1 inhibitors can synergize with cytarabine to increase its DNA damaging efficacy in AML ENSG00000149311 ENSG00000175054 ENSG00000276618 ENSG00000113456 ENSG00000123374 ENSG00000276876 ENSG00000138385 PMC6245348__F6 Molecular network and proposed mechanism of activity.Notes: (A) The predicted mechanism for the reversal of cell survival, angiogenesis, and inhibition of apoptosis ENSG00000002330 ENSG00000198793 ENSG00000112715 ENSG00000146648 ENSG00000064012 PMC4622404__F2 N-Glycan biosynthetic pathways in induced pluripotent stem cells (iPSCs), iPSC-derived cardiomyocytes, and human cardiomyocytes ENSG00000073849 ENSG00000126091 ENSG00000128268 PMC10935410__F4 Protein-to-protein subnetworks involved in prolactin, leptin, BDNF, and neurotrophin signaling pathways in CD4+ lymphocytes ENSG00000002330 ENSG00000170027 ENSG00000109320 ENSG00000291971 ENSG00000198793 ENSG00000169047 ENSG00000173039 ENSG00000213341 ENSG00000171791 ENSG00000196396 ENSG00000168610 ENSG00000141968 ENSG00000008056 ENSG00000160691 ENSG00000179295 ENSG00000084676 ENSG00000173757 ENSG00000010810 PMC8599049__F8 Interleukin 6 trans-signaling increases prostaglandin E2 production in human granulosa cells ENSG00000073756 PMC312710__F8 RegA regulation by differential degradation ENSG00000150991 ENSG00000113558 PMC5961063__F1 Summary of ROS modulation during ECM detachment ENSG00000026508 ENSG00000100033 ENSG00000023909 ENSG00000026103 PMC8639021__F3 Neurobiology of COVID-19: how can the virus affect the brain? ENSG00000213928 ENSG00000130234 ENSG00000184012 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC9323154__F1 Natural Products of Marine Origin for the Treatment of Colorectal and Pancreatic Cancers: Mechanisms and Potential ENSG00000002330 ENSG00000168040 ENSG00000026103 PMC5584049__F6 AC6 and AC6-ΔN signaling ENSG00000182533 ENSG00000291971 ENSG00000168610 PMC5821947__F1 Regulation of expression and functional role of CD38 PMC4643957__F9 Variations in Glycogen Synthesis in Human Pluripotent Stem Cells with Altered Pluripotent States ENSG00000281324 ENSG00000162337 PMC11914587__F10 TGFB signaling PMC8763503__F8 STAT6/VDR Axis Mitigates Lung Inflammatory Injury by Promoting Nrf2 Signaling Pathway PMC5359955__F2 Title: In PI3K-Akt-mTOR signaling pathway, PI3K inhibits autophagy via activation of Akt ENSG00000198793 PMC6094490__F1 Toll-like receptor (TLR) signaling pathways ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000276561 ENSG00000164342 PMC11914587__F14 Mitophagy in neurons ENSG00000142082 ENSG00000145782 ENSG00000168610 PMC4127946__F9 Proposed model for the role of CD28, CTLA-4, CD80, and the PD-1/PD-L pathway in mice after ischemic stroke ENSG00000134982 PMC7047153__F1 Innate immunity and antiretroviral activities ENSG00000172936 ENSG00000276561 PMC11914587__F11 Interactions between astrocytes, microglia and neurons leading to neuroinflammation ENSG00000162711 ENSG00000170458 ENSG00000125538 PMC3785965__F4 p120catenin regulation of Rho-GTPase signalling ENSG00000070831 ENSG00000160293 PMC8970045__F3 Full Functional Sex Reversal Achieved Through Silencing of MroDmrt11E Gene in Macrobrachium rosenbergii: Production of All-Male Monosex Freshwater Prawn ENSG00000100387 ENSG00000198793 ENSG00000113558 ENSG00000198168 ENSG00000117399 ENSG00000135506 PMC8970045__F4 Full Functional Sex Reversal Achieved Through Silencing of MroDmrt11E Gene in Macrobrachium rosenbergii: Production of All-Male Monosex Freshwater Prawn ENSG00000162552 ENSG00000132646 ENSG00000123374 PMC7287096__F5 Schematics of trafficking deficits mediated by pathogenic LRRK2 or knockdown of Rab8a ENSG00000167461 ENSG00000146648 PMC9070300__F2 Microglia-Mediated Inflammation and Neural Stem Cell Differentiation in Alzheimer’s Disease: Possible Therapeutic Role of KV1.3 Channel Blockade ENSG00000162711 ENSG00000010810 ENSG00000125538 ENSG00000136869 PMC7287096__F4 Schematics of EGFR degradation and recycling assays ENSG00000167461 ENSG00000138798 ENSG00000146648 PMC7924360__F1 Modification of PtdIns Mediated by PI3K, PTEN, SHIP, INPP4 and the PI3K signaling pathway in cancer: The phosphorylated state of inositol lipids inserted in the cell membrane is controlled by inositol kinase and phosphatase enzymes ENSG00000124102 PMC2975490__F1 Wnt-Related Molecules and Signaling Pathway Equilibrium in Hematopoiesis ENSG00000087095 ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC9284871__F7 Mesenchymal stem cells-derived small extracellular vesicles alleviate diabetic retinopathy by delivering NEDD4 ENSG00000178860 ENSG00000197713 ENSG00000069869 PMC4349708__F3 Mining Host-Pathogen Protein Interactions to Characterize Burkholderia mallei Infectivity Mechanisms ENSG00000053747 ENSG00000110330 ENSG00000002330 ENSG00000070831 ENSG00000010810 ENSG00000197702 ENSG00000136068 PMC8039192__F2 Molecular mechanism of the Hippo signaling cascade ENSG00000150457 ENSG00000131023 PMC8039192__F3 Mechanism of the lncRNA-mediated regulation of Hippo pathway in cancer ENSG00000126016 ENSG00000139926 ENSG00000150457 ENSG00000131023 PMC4083090__F7 A model of the role for ATRIP SUMOylation in the ATR pathway ENSG00000175054 ENSG00000164053 PMC8912926__F7 Potential regulatory network of androgens and progestins regulating testis organization and spermatogenesis via Insl3 ENSG00000248099 PMC7564391__F5 Major lncRNAs involved in taxane resistance ENSG00000135446 ENSG00000170145 ENSG00000171791 PMC2929310__F3 Transcript abundance patterns in Kawasaki disease patients with IVIG resistance ENSG00000051523 ENSG00000104899 ENSG00000073060 ENSG00000092067 ENSG00000115239 ENSG00000049249 PMC8310668__F9 Proposed schema of AZ, SFN, and AZ+SFN targeting the pro-survival pathways in BC ENSG00000175793 ENSG00000173599 ENSG00000079999 PMC8501670__F3 Caenorhabditis elegans as a model for obesity research ENSG00000083857 ENSG00000165323 ENSG00000026103 PMC4792095__F1 Inhibition of guanylate biosynthesis enzymes limits tumor invasion and growth ENSG00000106348 ENSG00000178035 ENSG00000137198 PMC2929310__F6 Transcript abundance patterns in Kawasaki disease patients with IVIG resistance PMC11462682__F2 Hexosamine biosynthesis pathway and cardiac function ENSG00000147162 ENSG00000198408 PMC8591138__F6 Identification of Cross-Pathway Connections via Protein-Protein Interactions Linked to Altered States of Metabolic Enzymes in Cervical Cancer ENSG00000198793 ENSG00000163918 ENSG00000170606 ENSG00000087586 ENSG00000164327 ENSG00000112118 ENSG00000132485 ENSG00000145386 ENSG00000183735 ENSG00000105325 ENSG00000011422 ENSG00000106245 ENSG00000119608 ENSG00000162521 ENSG00000179094 ENSG00000164342 ENSG00000005339 ENSG00000127191 ENSG00000117399 ENSG00000094804 ENSG00000135446 ENSG00000197959 ENSG00000005381 ENSG00000133119 ENSG00000198625 PMC6770969__F6 KEGG AMPK signaling ENSG00000180210 ENSG00000171105 ENSG00000198793 ENSG00000001626 ENSG00000164087 ENSG00000102977 ENSG00000026103 PMC2994033__F1 Signaling complexes are induced by TNFA to mediate NFKB activation, apoptosis, and necroptosis ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000127191 PMC9187215__F1 Dysregulation of Type 1 Interferon Signaling in Systemic Sclerosis: a Promising Therapeutic Target? ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000140968 ENSG00000276561 PMC2775888__F2 Cellular mechanisms by which flavonoids and their metabolites protect against neuroinflammation and neuronal injury induced by 5-S-Cys-DA, DHBT-1 and related ROS ENSG00000111537 ENSG00000002330 ENSG00000115415 PMC9187215__F2 Dysregulation of Type 1 Interferon Signaling in Systemic Sclerosis: a Promising Therapeutic Target? ENSG00000105397 ENSG00000115415 PMC9099786__F2 Dissecting the Functional Role of the TRIM8 Protein on Cancer Pathogenesis ENSG00000111537 ENSG00000171206 ENSG00000168610 PMC6889432__F5 Notch, PI3K, TGFB, Wnt/B-catenin, and EGFR/Ras signaling pathways are interacting with each other ENSG00000134982 ENSG00000198793 ENSG00000146648 PMC7147523__F4 CD11c+ microglia as a subset of microglia present through life and across conditions ENSG00000149311 ENSG00000198053 ENSG00000184371 PMC4592238__F10 Small Molecule DAM Inhibitor, Pyrimidinedione, Disrupts Streptococcus pneumoniae Biofilm Growth In Vitro ENSG00000159224 ENSG00000150787 PMC5980750__F1 Hippo-Yap signaling in ocular development and disease ENSG00000126016 ENSG00000159216 ENSG00000132849 ENSG00000131023 PMC8386298__F2 Moving Towards Targeted Therapies for Triple-Negative Breast Cancer ENSG00000198793 PMC6889432__F1 EGFR and PI3K signaling pathways in CRC ENSG00000102034 ENSG00000138798 ENSG00000198793 ENSG00000136997 ENSG00000146648 PMC6889432__F2 Notch signaling pathways in CRC ENSG00000110799 ENSG00000137845 ENSG00000101752 PMC10040549__F1 Ferroptosis in non-alcoholic liver disease: Molecular mechanisms and therapeutic implications ENSG00000111684 ENSG00000115107 PMC5241340__F8 Hypothesis of miR-567 modulation in healthy and BC cells PMC9576411__F2 Oxidative Stress and Intervertebral Disc Degeneration: Pathophysiology, Signaling Pathway, and Therapy ENSG00000162711 ENSG00000079999 PMC7226482__F2 Caspase-dependent and -independent apoptosis pathways utilized by cytotoxic T-cells (CTLs) and NK-cells and mechanisms of bone marrow microenvironment-mediated immune resistance ENSG00000178860 ENSG00000019991 ENSG00000213619 ENSG00000168040 ENSG00000168610 PMC8007632__F7 Cancer-associated fibroblasts-mediated ATF4 expression promotes malignancy and gemcitabine resistance in pancreatic cancer via the TGFB1/SMAD2/3 pathway and ABCC1 transactivation ENSG00000128272 ENSG00000105329 PMC3823134__F2 Schematic pathway of different steps of autophagy ENSG00000177169 ENSG00000198793 ENSG00000171791 ENSG00000145782 PMC1410736__F1 Disposition of 17Beta-estradiol (E2) and metabolites ENSG00000196502 PMC8641993__F1 Signaling Pathway of PGE2 and Its Regulatory Role in T Cell Differentiation PMC8988245__F2 Endoplasmic Reticulum Stress of Gut Enterocyte and Intestinal Diseases ENSG00000128272 ENSG00000116688 ENSG00000100219 PMC3756827__F1 Sirt3 deacetylation targets, and regulation of Sirt3 expression and activity ENSG00000142082 PMC9006951__F2 Alzheimer’s Disease: An Update and Insights Into Pathophysiology ENSG00000149968 ENSG00000138495 ENSG00000131095 ENSG00000100985 ENSG00000215045 ENSG00000122194 PMC5509684__F7 Statistically differentially expressed genes ENSG00000111537 ENSG00000147162 ENSG00000071073 ENSG00000115339 ENSG00000173039 ENSG00000162924 ENSG00000187210 ENSG00000128268 ENSG00000140297 ENSG00000179163 PMC9006951__F1 Alzheimer’s Disease: An Update and Insights Into Pathophysiology ENSG00000066468 ENSG00000140285 PMC419935__F8 A working model for the CblSTR signal transduction pathway ENSG00000142273 PMC9589357__F4 Transcriptome analysis of malate-induced Schizochytrium sp. FJU-512 reveals a novel pathway for biosynthesis of docosahexaenoic acid with enhanced expression of genes responsible for acetyl-CoA and NADPH accumulation ENSG00000065833 ENSG00000073578 ENSG00000173599 ENSG00000062485 ENSG00000026103 PMC11668798__F2 Sphingolipid rheostat targeting in adult-type diffuse gliomas ENSG00000162407 ENSG00000285281 ENSG00000067113 ENSG00000141934 ENSG00000143418 ENSG00000139624 ENSG00000198964 ENSG00000223802 ENSG00000154227 ENSG00000164023 ENSG00000166224 ENSG00000119537 ENSG00000163082 PMC12027064__F2 The microbiota-induced expression of MMPs during OSCC ENSG00000081041 ENSG00000187800 PMC12027064__F3 Microbiota-induced expression of MMPs in ECM remodeling during IBD and CRC ENSG00000136869 PMC11720488__F1 Dysregulated Signaling Pathways in Canine Mammary Tumor and Human Triple Negative Breast Cancer: Advances and Potential Therapeutic Targets ENSG00000142910 ENSG00000112655 ENSG00000120075 ENSG00000146648 PMC11720488__F2 Dysregulated Signaling Pathways in Canine Mammary Tumor and Human Triple Negative Breast Cancer: Advances and Potential Therapeutic Targets ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000186654 PMC4428393__F2 Cytoplasmic folate-mediated one-carbon metabolism is required for de novo purine, thymidylate, and methionine synthesis ENSG00000100714 PMC1481516__F2 Metabolic pathway and bioenergetics of net citrate production in prostate cells ENSG00000122966 ENSG00000172005 ENSG00000062485 PMC9278000__F2 Recent clinical findings on the role of kinase inhibitors in COVID-19 management ENSG00000162711 ENSG00000130234 ENSG00000125538 ENSG00000010671 PMC8946707__F1 Understanding the Notch Signaling Pathway in Acute Myeloid Leukemia Stem Cells: From Hematopoiesis to Neoplasia ENSG00000148400 ENSG00000074181 PMC6067656__F1 Schematic representation of human adrenal steroidogenesis ENSG00000277893 ENSG00000203859 ENSG00000127948 PMC11790428__F1 Signaling pathway of NOD1 ENSG00000125538 ENSG00000163914 ENSG00000131323 ENSG00000106100 ENSG00000276561 PMC7439808__F6 Reductive Glutamine Metabolism and Serine-Driven Folate Metabolism Suppresses Mitochondrial ROS Accumulation to Support Anchorage-Independent Growth and/or Metastatic Disease ENSG00000065911 ENSG00000100714 ENSG00000120254 PMC8440421__F5 Chitosan-mediated cGAS-STING and inflammasome activation, and the promotion of Th1 responses ENSG00000162711 ENSG00000183735 ENSG00000164430 ENSG00000111537 ENSG00000125538 PMC4891098__F6 WISP-1 promotes VEGF-C-dependent lymphangiogenesis by inhibiting miR-300 in human oral squamous cell carcinoma cells ENSG00000150630 PMC8909980__F6 Inflammatory Cytokine Production in Human Monocytes by cGMP and IRAK3 ENSG00000173039 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000090376 ENSG00000184216 PMC8992488__F2 Glioblastoma chemoresistance: roles of the mitochondrial melatonergic pathway ENSG00000133937 ENSG00000106546 PMC6512043__F8 T10 inhibited NFKB activity via miR155-5p/SHIP1 axis ENSG00000174125 ENSG00000136869 ENSG00000175104 PMC10572156__F7 Beta-Sitosterol Suppresses Lipopolysaccharide-Induced Inflammation and Lipogenesis Disorder in Bovine Mammary Epithelial Cells ENSG00000198793 ENSG00000169710 ENSG00000099194 PMC11015656__F1 Mechanistic insights and the clinical prospects of targeted therapies for glioblastoma: a comprehensive review ENSG00000019991 ENSG00000291971 ENSG00000138798 ENSG00000163914 ENSG00000155792 ENSG00000170430 ENSG00000146648 PMC175791__F10 Differential regulation of NFAT and SRF by the B cell receptor via a PLCG–Ca2+-dependent pathway ENSG00000070831 ENSG00000186716 ENSG00000010671 PMC3979452__F4 MiRNA regulation of skin fibrosis in epithelial and fibroblast cells ENSG00000169554 PMC11015656__F2 20S proteasome inhibitors and their targets ENSG00000134057 ENSG00000135446 ENSG00000123374 ENSG00000205250 PMC8834318__F4 Cisplatin Resistance in HPV Negative Head and Neck Squamous Cell Carcinomas ENSG00000150093 PMC3298845__F1 Wnt/Beta-catenin signaling pathway in liver biology and disease ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6599650__F1 Schematic illustration of the formation of pH- and redox-responsive, methotrexate-loaded, APP-derived micelles via self-assembly in aqueous solution ENSG00000087245 ENSG00000142192 ENSG00000100985 PMC9626535__F10 MiR-93-5p promotes granulosa cell apoptosis and ferroptosis by the NF-kB signaling pathway in polycystic ovary syndrome ENSG00000167468 ENSG00000171791 PMC400410__F5 Functional associations of genes identified by discriminant function analysis (DFA) in patients with juvenile rheumatoid arthritis (JRA) who were undergoing treatment ENSG00000059804 ENSG00000105329 ENSG00000165030 ENSG00000120885 ENSG00000135404 ENSG00000136689 PMC400410__F3 Functional associations of genes selected as differentially expressed in patients with juvenile rheumatoid arthritis (JRA) and normal controls ENSG00000142192 ENSG00000111537 ENSG00000110395 ENSG00000291971 ENSG00000157601 ENSG00000149308 ENSG00000273686 ENSG00000164305 ENSG00000171051 PMC400410__F4 Functional associations of hypervariable (HV) genes in patients with juvenile rheumatoid arthritis (JRA) ENSG00000006194 ENSG00000112977 ENSG00000224320 ENSG00000111537 ENSG00000105329 ENSG00000153201 ENSG00000129152 PMC5932495__F2 The role of inflammasomes in Parkinson's disease and Alzheimer's disease ENSG00000162711 ENSG00000281166 ENSG00000172936 PMC5463201__F2 Endogenous sources and consequences of ROS overproduction ENSG00000137857 ENSG00000140279 ENSG00000086991 ENSG00000074771 PMC5463201__F3 Examples of NOX signal transduction ENSG00000087245 ENSG00000086991 ENSG00000168610 PMC1804347__F4 Systemic sclerosis: a prototypic multisystem fibrotic disorder ENSG00000070831 ENSG00000163914 ENSG00000185591 PMC10987301__F3 visually outlines the RAS/microRNAs (miRNAs) pathway in cancer metastasis, emphasizing the pivotal role of the Ras signaling pathway, particularly in tumor initiation and metastasis ENSG00000068028 PMC8166856__F7 STAT3 in gefitinib resistance ENSG00000291971 ENSG00000168610 ENSG00000146648 PMC7490765__F5 Molecular basis of drug resistance in cancer ENSG00000149311 ENSG00000175054 ENSG00000291971 ENSG00000198793 ENSG00000146648 PMC3438084__F6 A subset of the up-regulated genes with known function in response to maize root exudates ENSG00000150787 PMC4193161__F8 A simple model was constructed on the basis of transcriptome data ENSG00000105722 ENSG00000173599 PMC6695670__F2 Toll-like receptor (TLR) signaling ENSG00000174123 ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC5983921__F3 Wnt/Beta-catenin signaling pathway ENSG00000162337 ENSG00000134982 ENSG00000183579 ENSG00000168036 ENSG00000167074 PMC8585982__F1 CAR-T: a potential gene carrier targeting solid tumor immune microenvironment PMC5412337__F1 Current strategies for targeting the epidermal growth factor receptor (EGFR) pathway ENSG00000019991 ENSG00000138798 ENSG00000198793 ENSG00000168610 PMC8748960__F4 Training associated alterations in equine respiratory immunity using a multiomics comparative approach ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000111837 ENSG00000033800 ENSG00000125347 PMC8497895__F2 Harnessing DNA Repair Defects to Augment Immune-Based Therapies in Triple-Negative Breast Cancer ENSG00000149311 ENSG00000175054 ENSG00000164430 ENSG00000134982 ENSG00000163599 PMC11794105__F1 Signaling pathway regulating EMT in epithelial cells ENSG00000134982 ENSG00000177606 ENSG00000168036 PMC8497895__F1 Harnessing DNA Repair Defects to Augment Immune-Based Therapies in Triple-Negative Breast Cancer ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000051180 ENSG00000138385 PMC4158168__F6 Signaling pathway that metformin uses to regulate T cell and osteoclasts in autoimmune arthritis ENSG00000198793 ENSG00000175104 ENSG00000168610 PMC7483800__F3 SARM1 Axon Degeneration Pathway: Control of the NAD+ Metabolome Regulates Axon Survival in Health and Disease ENSG00000105835 ENSG00000123572 ENSG00000278488 PMC7831909__F2 Sulforaphane targets Nrf2 pathway to prevent kidney disease progression ENSG00000181019 ENSG00000162692 ENSG00000187134 ENSG00000079999 PMC7483800__F1 SARM1 Axon Degeneration Pathway: Control of the NAD+ Metabolome Regulates Axon Survival in Health and Disease ENSG00000104435 ENSG00000113558 ENSG00000157064 PMC6492912__F1 The nicotinamide adenine dinucleotide (NAD) biosynthetic pathways in mammals ENSG00000105835 ENSG00000123572 ENSG00000278488 PMC3721034__F2 MDM2-p53 pathway revisited ENSG00000149311 ENSG00000064393 ENSG00000167967 ENSG00000078237 ENSG00000284194 PMC10991944__F1 Metabolic engineering of methylotrophic Pichia pastoris for the production of Beta-alanine ENSG00000204653 ENSG00000122966 ENSG00000172005 PMC11670207__F6 Identification of key genes related to growth of largemouth bass (Micropterus salmoides) based on comprehensive transcriptome analysis ENSG00000150907 ENSG00000177606 ENSG00000173039 ENSG00000132326 ENSG00000096717 ENSG00000168610 ENSG00000124762 ENSG00000132170 PMC3721034__F5 MDM2-p53 pathway revisited ENSG00000281766 ENSG00000152409 ENSG00000121481 ENSG00000064393 ENSG00000161970 ENSG00000140464 PMC11670207__F7 DEGs in growth-related pathways ENSG00000104365 ENSG00000240445 ENSG00000198793 ENSG00000171608 ENSG00000124253 ENSG00000100485 ENSG00000168610 ENSG00000133818 PMC11659141__F4 Complement and coagulation genes are differentially expressed in head kidney samples between A ENSG00000062485 PMC3066048__F1 Complementation of Saccharomyces cerevisiae coq7 Mutants by Mitochondrial Targeting of the Escherichia coli UbiF Polypeptide ENSG00000132423 ENSG00000119723 ENSG00000110871 ENSG00000173085 PMC5165248__F1 Simplified schematic depiction of a hypothetic PrPc-induced signaling cross-talk between PI3K/Akt and Wnt/Beta-catenin pathway under hypoxic conditions ENSG00000168036 PMC7603558__F6 Signaling pathways involved in the actions of the 12 herbs against OvCa ENSG00000136869 ENSG00000026103 PMC2687355__F7 The signaling pathway MyD88 ⇒ p38 ⇒ EGR-1/AP-1 is essential for GBS-induced transcriptional activation of TNF ENSG00000172005 PMC8110832__F3 Interplay Between Glucose Metabolism and Chromatin Modifications in Cancer ENSG00000105835 ENSG00000262217 ENSG00000096717 ENSG00000081189 PMC8110832__F1 Interplay Between Glucose Metabolism and Chromatin Modifications in Cancer ENSG00000168036 ENSG00000124253 ENSG00000146648 ENSG00000159399 PMC2637482__F2 Crosstalk between Robo4/Slit2 and VEGF signaling pathways ENSG00000145147 ENSG00000154133 PMC6485244__F2 NFKB-BRD4 signaling in innate inflammation and remodeling ENSG00000141867 ENSG00000124216 ENSG00000173039 ENSG00000276561 PMC7503576__F1 Bile acid synthesis pathways ENSG00000167910 ENSG00000180432 ENSG00000115271 ENSG00000135929 PMC8045781__F2 Oncogenic RAS-dependent control of cellular metabolism ENSG00000125166 ENSG00000065833 ENSG00000197713 ENSG00000074800 ENSG00000198380 ENSG00000167468 ENSG00000169710 ENSG00000153574 ENSG00000115419 ENSG00000159399 PMC5406893__F7 Summary of the survival and growth phenotypes in breast cancer ENSG00000002330 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC5790481__F13 Melatonin attenuated brain death tissue extract-induced cardiac damage by suppressing DAMP signaling ENSG00000150782 ENSG00000065833 ENSG00000170458 ENSG00000125538 ENSG00000172005 ENSG00000189403 ENSG00000172936 ENSG00000136869 PMC11682973__F1 The PI3K/AKT/mTOR signaling pathway ENSG00000177169 ENSG00000163435 ENSG00000117525 ENSG00000123395 ENSG00000150907 ENSG00000169047 PMC7692672__F1 Synthesis and metabolism of sphingolipids (SLs) ENSG00000173599 ENSG00000115419 PMC9465647__F1 Resveratrol on rheumatoid arthritis: From bench to bedside ENSG00000173039 ENSG00000096717 ENSG00000079999 PMC7736467__F6 Cannabinoid signaling pathways affecting neuronal extension length ENSG00000012048 ENSG00000291971 ENSG00000168610 PMC9125579__F10 Contribution of Mitochondria to Insulin Secretion by Various Secretagogues ENSG00000135218 ENSG00000042832 ENSG00000144935 ENSG00000167323 ENSG00000293604 ENSG00000158669 ENSG00000070985 ENSG00000138741 ENSG00000186281 ENSG00000132639 ENSG00000147262 PMC5078498__F1 Dopaminergic miRNA nodes in a rich network of connections in synaptic plasticity pathways ENSG00000106617 ENSG00000187446 PMC7082880__F5 Drugs targeting Wnt pathways in cancer treatments ENSG00000281324 ENSG00000162337 ENSG00000112655 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC11576406__F4 Pathways significantly affected by shear stress in HBMECs(A) Effects of physiological shear stress (1 ENSG00000163464 ENSG00000169248 ENSG00000107562 ENSG00000130528 ENSG00000163739 ENSG00000112561 ENSG00000150093 ENSG00000124875 ENSG00000121966 ENSG00000116815 ENSG00000041982 ENSG00000138755 ENSG00000188404 ENSG00000163734 ENSG00000169429 ENSG00000154721 ENSG00000076662 ENSG00000139626 ENSG00000149564 ENSG00000124102 ENSG00000081041 ENSG00000169896 ENSG00000090863 ENSG00000156026 ENSG00000007908 ENSG00000150637 ENSG00000292348 ENSG00000169245 ENSG00000186810 ENSG00000182533 ENSG00000261371 ENSG00000161921 ENSG00000186716 ENSG00000174059 ENSG00000115232 PMC7082880__F2 Wnt signaling pathways ENSG00000070831 ENSG00000134982 ENSG00000030304 ENSG00000167074 ENSG00000168036 ENSG00000150457 ENSG00000131023 ENSG00000168610 ENSG00000010810 ENSG00000163914 ENSG00000177606 ENSG00000112655 ENSG00000108375 PMC11576406__F6 Pathways significantly affected by iRBC exposure in HMBECs(A) The endosomal signaling pathway was affected by co-incubation with ring stage iRBCs and shear stress (1 ENSG00000163464 ENSG00000169248 ENSG00000107562 ENSG00000070831 ENSG00000291971 ENSG00000163739 ENSG00000124875 ENSG00000165527 ENSG00000121966 ENSG00000111737 ENSG00000102189 ENSG00000130164 ENSG00000009844 ENSG00000138755 ENSG00000163734 ENSG00000169429 ENSG00000154721 ENSG00000084733 ENSG00000024422 ENSG00000114520 ENSG00000149564 ENSG00000081041 ENSG00000013016 ENSG00000115561 ENSG00000112335 ENSG00000074319 ENSG00000069329 ENSG00000131475 ENSG00000292348 ENSG00000169245 ENSG00000176108 ENSG00000186810 ENSG00000261371 ENSG00000161921 ENSG00000078053 ENSG00000028528 PMC6305747__F2 Pentraxins-expanded network of complement activation and regulation ENSG00000163661 ENSG00000132693 PMC7078296__F7 Helicobacter pylori-induced adrenomedullin modulates IFN-Gamma-producing T-cell responses and contributes to gastritis ENSG00000148926 ENSG00000038002 ENSG00000131477 ENSG00000168610 PMC4369672__F1 Intracellular signaling proposed to be involved in the inflammatory response during immune-mediated joint diseases such as aseptic loosening ENSG00000174125 ENSG00000171855 ENSG00000143546 ENSG00000167207 ENSG00000137033 ENSG00000163220 ENSG00000163565 ENSG00000150455 ENSG00000106100 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000125538 ENSG00000189403 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC4369672__F2 Simplified overview of the RA-associated inflammation-promoting factors ENSG00000154342 ENSG00000169071 ENSG00000125538 ENSG00000050165 ENSG00000106483 PMC7163451__F8 Schematic diagram about the central role of co-treatment with Beta-elemene and cetuximab in ferroptosis induction and migration inhibition ENSG00000168003 ENSG00000138449 ENSG00000151012 ENSG00000167468 ENSG00000115107 PMC8706759__F1 Targeting DNA repair pathway in cancer: Mechanisms and clinical application ENSG00000149311 ENSG00000175054 ENSG00000132646 ENSG00000039650 ENSG00000227345 ENSG00000138385 ENSG00000139618 PMC8706759__F3 Targeting DNA repair pathway in cancer: Mechanisms and clinical application ENSG00000149311 ENSG00000175054 ENSG00000164430 PMC11455816__F8 Schematic of MAGL blockade-mediated protection from GC-induced bone homeostasis imbalance ENSG00000168036 PMC8618597__F5 Leucosceptoside A from Devil’s Claw Modulates Psoriasis-like Inflammation via Suppression of the PI3K/AKT Signaling Pathway in Keratinocytes ENSG00000284881 ENSG00000108691 ENSG00000148773 ENSG00000115415 ENSG00000285433 ENSG00000112115 ENSG00000143556 ENSG00000073756 ENSG00000115009 PMC8485741__F1 Induction and Evasion of Type-I Interferon Responses during Influenza A Virus Infection ENSG00000213928 ENSG00000088888 ENSG00000187608 ENSG00000105397 ENSG00000115415 ENSG00000157601 ENSG00000172936 ENSG00000121060 ENSG00000276561 ENSG00000164342 PMC4172968__F11 Schematic representation of the signaling pathway proposed for the AhR-dependent control of cell migration ENSG00000291971 ENSG00000106546 PMC10459054__F1 Typical pathway of miRNA formation ENSG00000128191 ENSG00000113360 ENSG00000132341 PMC10459054__F4 Natural Products Treat Colorectal Cancer by Regulating miRNA ENSG00000011304 ENSG00000149968 PMC10459054__F2 Anti-cancer mechanisms of five agents (1) resveratrol induces growth inhibition and apoptosis in colon cancer DLD-1 cells by reducing miRNA-96 expression through MAPK/ERK1/2 signaling pathway activation ENSG00000065361 ENSG00000198793 ENSG00000140297 ENSG00000168610 ENSG00000146648 PMC9254480__F1 VEGF/VEGFR-Targeted Therapy and Immunotherapy in Non-small Cell Lung Cancer: Targeting the Tumor Microenvironment ENSG00000162889 ENSG00000165197 ENSG00000002330 ENSG00000070831 ENSG00000010810 ENSG00000198793 ENSG00000112715 ENSG00000118257 ENSG00000150630 PMC9546106__F2 Neutrophil granule proteins in orchestrating inflammation and immunity ENSG00000239732 PMC4378458__F4 NAD+biosynthetic pathways ENSG00000105835 ENSG00000278488 PMC9666786__F1 Crosstalk between enteric serotonergic neurons and colorectal cancer stem cells to initiate colorectal tumorigenesis ENSG00000139287 ENSG00000179097 ENSG00000168036 ENSG00000179546 PMC11287639__F1 SMAD4 in the transforming growth factor-beta (TGFB) signalling pathway ENSG00000107779 ENSG00000121989 ENSG00000170365 ENSG00000120693 ENSG00000204217 ENSG00000163217 ENSG00000114739 PMC2778287__F6 Schematic representation of a dualistic model depicting the development of ovarian cancer ENSG00000012048 ENSG00000157764 ENSG00000146648 ENSG00000139618 PMC2678157__F9 The steroid synthesis pathway showing genes regulated in this study ENSG00000099377 ENSG00000176387 PMC6317954__F4 Metformin combined with Abs or small molecular inhibitors in cancer treatment ENSG00000198793 ENSG00000146648 PMC3146784__F2 TLR ligands and signalling ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000276561 ENSG00000164342 PMC9437261__F7 Dapagliflozin protects against nonalcoholic steatohepatitis in db/db mice ENSG00000114416 ENSG00000100985 ENSG00000168610 ENSG00000026103 PMC6317954__F1 General molecular mechanisms of metformin on inhibiting cancer cell growth ENSG00000198793 ENSG00000140443 PMC4691138__F1 Schematic presentation of proposed molecular epigenetic mechanism of sulforaphane’s action including interdependence between histone modification and DNA methylation ENSG00000175793 ENSG00000132646 ENSG00000118971 PMC9299441__F8 Neutrophil Survival Signaling During Francisella tularensis Infection ENSG00000002330 PMC5382021__F6 Group B Streptococcus degrades cyclic-di-AMP to modulate STING-dependent type I interferon production ENSG00000183735 ENSG00000164430 PMC7565808__F1 Micropeptides encoded by lncRNAs regulate tumor malignant behaviorsa Linc00998 encodes micropeptide SMIM30 promotes HCC development by inducing SRC/YES1 membrane anchoring and MAPK pathway activation ENSG00000267795 ENSG00000104549 ENSG00000168610 ENSG00000101425 PMC8041881__F4 IL-17 signaling pathway ENSG00000148346 ENSG00000102871 ENSG00000105656 ENSG00000113520 ENSG00000162924 ENSG00000131323 ENSG00000168040 ENSG00000155313 PMC11978694__F5 MiRNA in treatment of gout arthritis ENSG00000162711 ENSG00000169554 ENSG00000102908 ENSG00000124882 ENSG00000127528 ENSG00000172936 ENSG00000136869 ENSG00000112715 PMC4306190__F4 Diabetes Mellitus and Blood-Brain Barrier Dysfunction: An Overview ENSG00000189403 ENSG00000162692 PMC7139574__F1 Biological pathways involved in chronic lymphocytic leukemia (CLL) pathogenesis and harboring therapeutic implications ENSG00000023445 ENSG00000104856 ENSG00000149311 ENSG00000186716 ENSG00000197943 ENSG00000111321 ENSG00000131323 ENSG00000127191 ENSG00000010671 ENSG00000109670 PMC6549020__F1 cTAZ: a safeguard factor of antiviral response ENSG00000183735 ENSG00000213928 ENSG00000123612 ENSG00000115415 ENSG00000049768 PMC11978694__F2 Molecular pathways involved in gouty arthritis and potential miRNA regulators ENSG00000278718 ENSG00000162711 ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000096717 PMC9663420__F6 P2RX receptors and inflammatory markers in SCZ ENSG00000196136 ENSG00000162711 ENSG00000089041 ENSG00000135124 PMC3185489__F1 Diagram connecting the insulin pathway and fatty acid (FA) biosynthesis ENSG00000169047 ENSG00000198793 ENSG00000198670 ENSG00000099194 ENSG00000026103 PMC7240781__F8 Crosstalk between the adrenal steroidogenic regulatory network and the immune pathway ENSG00000030582 ENSG00000082175 ENSG00000125538 PMC5483452__F8 Schematic illustrating the role of Nupr1 in METH-induced apoptosis and autophagy in neuronal cells ENSG00000101255 ENSG00000198793 ENSG00000176046 PMC8320172__F3 Is RAS the Link Between COVID-19 and Increased Stress in Head and Neck Cancer Patients? ENSG00000130234 ENSG00000198793 ENSG00000146648 PMC7730574__F5 Anti-inflammatory activity of Ep-ME when targeting TAK1 in the AP-1 signaling pathway ENSG00000177606 ENSG00000172936 ENSG00000136869 ENSG00000184216 ENSG00000164342 PMC6497798__F3 Targeting of host gene expression by Toxoplasma gondii ENSG00000120833 ENSG00000115415 ENSG00000137265 ENSG00000168610 PMC9589293__F2 Temporal proteomic analyses of human lung cells distinguish high pathogenicity influenza viruses and coronaviruses from low pathogenicity viruses ENSG00000113161 ENSG00000091592 ENSG00000091542 ENSG00000126261 ENSG00000169032 ENSG00000163631 ENSG00000102241 ENSG00000150991 ENSG00000178573 ENSG00000135049 ENSG00000204634 ENSG00000288475 ENSG00000176293 ENSG00000164631 ENSG00000136444 ENSG00000102313 ENSG00000086200 ENSG00000166349 ENSG00000109743 ENSG00000099194 ENSG00000175535 ENSG00000197530 ENSG00000127184 ENSG00000050165 ENSG00000291895 ENSG00000047849 ENSG00000146648 PMC9589293__F3 Temporal proteomic analyses of human lung cells distinguish high pathogenicity influenza viruses and coronaviruses from low pathogenicity viruses ENSG00000179934 ENSG00000112972 ENSG00000168036 ENSG00000128581 ENSG00000072195 ENSG00000008083 ENSG00000137807 ENSG00000136997 ENSG00000023892 ENSG00000090861 ENSG00000182916 ENSG00000243811 ENSG00000134376 ENSG00000263465 ENSG00000119688 ENSG00000164199 ENSG00000291662 ENSG00000005339 ENSG00000101236 ENSG00000163900 ENSG00000169989 ENSG00000142621 ENSG00000138709 ENSG00000213516 ENSG00000018408 ENSG00000013503 ENSG00000058866 ENSG00000258289 ENSG00000205683 ENSG00000071564 ENSG00000103018 ENSG00000243646 ENSG00000102974 PMC9589293__F4 Temporal proteomic analyses of human lung cells distinguish high pathogenicity influenza viruses and coronaviruses from low pathogenicity viruses ENSG00000131473 ENSG00000161544 ENSG00000134824 ENSG00000175592 ENSG00000080823 ENSG00000143479 ENSG00000183160 ENSG00000052802 ENSG00000104368 PMC5040224__F2 Major regulatory pathways involved in the regulation of Runx2, a chief transcriptional regulator of osteogenesis ENSG00000170365 ENSG00000138795 ENSG00000155011 ENSG00000168036 PMC6497798__F1 Autophagy initiates host immunity and Toxoplasma immune evasion ENSG00000144895 ENSG00000291971 ENSG00000168610 PMC7504854__F3 Mechanism by which A20 regulates arthritis ENSG00000278718 ENSG00000162711 ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000082512 ENSG00000125538 ENSG00000157625 ENSG00000172936 ENSG00000168404 ENSG00000175104 ENSG00000285379 PMC3185489__F4 The effects of HCV on steatosis development ENSG00000099194 ENSG00000026103 PMC11755957__F8 Cellular response in bovine sperm after frozen-thawed ENSG00000120885 PMC7640369__F6 Pathways in which radiosensitizing effects of c-myc gene knockdown induced G2/M phase arrest by intrinsic stimuli through the mitochondrial signaling pathway ENSG00000134057 PMC3185489__F2 Some of the effects brought about by HCV on insulin signaling in hepatocytes ENSG00000008710 ENSG00000169047 ENSG00000198793 PMC8436723__F4 Screening a Prognosis-Related Target Gene in Patients with HER-2-Positive Breast Cancer by Bioinformatics Analysis ENSG00000145604 ENSG00000094804 ENSG00000108055 ENSG00000179091 ENSG00000132646 ENSG00000115942 ENSG00000123374 ENSG00000073111 PMC3605881__F6 Scheme of mechanisms underlying attenuation of cardiac dysfunction induced by endotoxin, after NG-R1 treatment ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC8012432__F1 Novel Method to Differentiate Tonsil-Derived Mesenchymal Stem Cells In Vitro into Estrogen-Secreting Cells PMC10487928__F4 Gamma interactome of the top 20 most connected differentially expressed genes (DEGs), defense response to virus genes, angiogenesis genes, adaptive and innate immune genes, and SARS-CoV-2 proteins ENSG00000142627 ENSG00000187608 ENSG00000124610 ENSG00000275713 ENSG00000157601 ENSG00000275126 ENSG00000142512 ENSG00000122786 ENSG00000073111 ENSG00000145386 ENSG00000278545 ENSG00000133216 ENSG00000276410 ENSG00000108691 ENSG00000163235 ENSG00000108679 ENSG00000125170 ENSG00000111331 ENSG00000101213 ENSG00000125968 PMC6640647__F2 Simplified TGFB signaling pathways ENSG00000198793 ENSG00000136997 ENSG00000156574 ENSG00000123374 PMC8819604__F3 Pathophysiological Pathway Leading to the Development of Valve Calcification in Chronic Kidney Disease ENSG00000118972 ENSG00000152266 ENSG00000198670 ENSG00000169174 PMC3830198__F4 Model showing the proposed mechanisms of lncRNA-mediated regulation of the RB pathway ENSG00000135446 ENSG00000105810 PMC3830198__F5 Model showing the proposed mechanisms of lncRNA-mediated regulation of the p53 pathway ENSG00000149311 ENSG00000175054 PMC8132131__F4 Interplay between hydrogen sulfide and other signaling molecules in the regulation of guard cell signaling and abiotic/biotic stress response ENSG00000151657 PMC4369647__F2 Signaling pathway associated with CD37 ligation by SMIP-016 ENSG00000104894 ENSG00000168036 PMC11754069__F1 Intrahepatic network and metabolic signaling in NAFLD ENSG00000131473 ENSG00000178607 ENSG00000138823 ENSG00000138030 ENSG00000100219 PMC11754069__F2 Extrahepatic organ-specific networks associated with NAFLD ENSG00000159224 ENSG00000105550 ENSG00000113140 ENSG00000115138 PMC6460526__F2 CYLD-associated signaling pathways ENSG00000104856 ENSG00000102871 ENSG00000170558 ENSG00000177606 ENSG00000173039 ENSG00000168036 ENSG00000111321 ENSG00000083799 ENSG00000128602 ENSG00000127191 PMC10003241__F3 Metabolic Features of Osteoblasts: Implications for Multiple Myeloma (MM) Bone Disease ENSG00000281324 ENSG00000162337 ENSG00000108821 ENSG00000070669 ENSG00000115419 PMC4906788__F2 TGFB signaling pathway ENSG00000049323 ENSG00000111537 ENSG00000095739 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000205250 ENSG00000137801 PMC4755536__F7 De Novo Transcriptome Assembly and Characterization for the Widespread and Stress-Tolerant Conifer Platycladus orientalis ENSG00000163435 ENSG00000203783 PMC7400738__F2 Biogenesis, secretion, composition, and application of exosomes as liquid biopsy ENSG00000074319 ENSG00000110651 ENSG00000010278 ENSG00000135404 PMC7001864__F1 Molecular Control of Canonical WNT Signaling ENSG00000107404 ENSG00000162337 ENSG00000134982 ENSG00000183762 ENSG00000102312 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000185269 PMC7001864__F3 Impact of WNT Signaling on Cancer Immunosurveillance ENSG00000123685 ENSG00000169245 ENSG00000049768 PMC10041388__F1 Metabolic reprogramming in cancer: Mechanisms and therapeutics ENSG00000074800 ENSG00000147162 ENSG00000159399 PMC6928102__F8 Proposed model of the EPHB2 signaling cascade that regulates the synaptic plasticity through the phosphorylation of AKT under neuroinflammation-associated perturbation of glutamatergic transmission ENSG00000090776 ENSG00000115419 PMC6905197__F1 Hippo signaling pathway ENSG00000114978 ENSG00000131023 PMC6928102__F5 Correlation network between the significantly changed metabolites and proteins of the hypothalamus in the LPS group compared with that in the CON group ENSG00000110237 ENSG00000151490 ENSG00000088179 ENSG00000116586 ENSG00000230989 ENSG00000179151 ENSG00000090776 ENSG00000196544 ENSG00000189159 ENSG00000130202 ENSG00000178188 ENSG00000183943 ENSG00000106070 ENSG00000168781 ENSG00000247077 PMC9653955__F13 Phytocannabinoid Compositions from Cannabis Act Synergistically with PARP1 Inhibitor against Ovarian Cancer Cells In Vitro and Affect the Wnt Signaling Pathway ENSG00000004975 ENSG00000187688 ENSG00000057593 ENSG00000168036 ENSG00000051180 PMC3820524__F1 Overview of hemostasis ENSG00000003436 ENSG00000134982 PMC7072767__F4 PINK1-Parkin pathway regulates IPAS expression and inhibits neuronal death ENSG00000158828 PMC7356809__F3 FAT10 is expressed in response to RNA virus infection and acts as a negative feedback regulator of RIG-I activation ENSG00000088888 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000276561 PMC6237963__F6 Cell cycle regulation pathway and the genes whose expressions were altered by 11-KT ENSG00000118007 ENSG00000108055 ENSG00000134982 ENSG00000205250 ENSG00000277273 ENSG00000101224 ENSG00000118971 ENSG00000166851 ENSG00000117399 ENSG00000276876 ENSG00000093009 ENSG00000145604 ENSG00000103479 ENSG00000094804 ENSG00000101972 ENSG00000150991 ENSG00000134057 ENSG00000135446 ENSG00000132646 ENSG00000135336 ENSG00000164754 ENSG00000105810 ENSG00000147082 ENSG00000175305 PMC6022559__F6 Subnetworks of breast cancer subtypes ENSG00000029559 ENSG00000165458 ENSG00000136997 ENSG00000173482 ENSG00000121067 ENSG00000137076 ENSG00000179094 ENSG00000182621 ENSG00000135503 ENSG00000121879 ENSG00000146648 ENSG00000198286 PMC5061729__F1 EGFR signaling pathway modified from MetaCore® ENSG00000110395 ENSG00000291971 ENSG00000124181 ENSG00000146648 ENSG00000140443 ENSG00000160691 PMC9009225__F5 Qinggan Huoxue Recipe Alleviates Alcoholic Liver Injury by Suppressing Endoplasmic Reticulum Stress Through LXR-LPCAT3 ENSG00000144895 ENSG00000111684 ENSG00000100219 ENSG00000123268 PMC8847441__F5 Oscillatory Behaviors of microRNA Networks: Emerging Roles in Retinal Development ENSG00000168214 ENSG00000148400 ENSG00000273529 ENSG00000114315 PMC11050203__F1 Activated signaling pathways: (a) the Wnt signaling pathway is activated in the presence of Wnt ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC8365519__F5 Low-Dose Radiation Can Cause Epigenetic Alterations Associated With Impairments in Both Male and Female Reproductive Cells ENSG00000144028 ENSG00000196531 ENSG00000143878 ENSG00000136997 ENSG00000177084 PMC10974426__F1 Virus-activated intracellular signaling pathways ENSG00000213928 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000125347 ENSG00000142166 PMC3962044__F1 NFKB signaling pathways in osteoclast lineage cells ENSG00000104856 ENSG00000157625 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC3962044__F3 IAP antagonists and NFKB signaling in osteoclast lineage cells ENSG00000104856 ENSG00000137275 ENSG00000102871 ENSG00000131323 ENSG00000127191 PMC6260925__F6 Senescence prevention by HO‐1 activation ENSG00000158828 PMC7120155__F11 Antifibrosis therapy ENSG00000198793 ENSG00000198670 ENSG00000111816 PMC5904200__F2 Simplified scheme of established complement activation pathways ENSG00000134830 ENSG00000203710 ENSG00000197405 ENSG00000196352 ENSG00000166278 ENSG00000132693 PMC7762936__F2 Post-translational regulation of the long and winding cholesterol synthesis pathway ENSG00000110921 ENSG00000172893 ENSG00000113161 ENSG00000120437 ENSG00000167508 ENSG00000160752 ENSG00000067064 ENSG00000145495 ENSG00000132196 ENSG00000116133 ENSG00000143815 ENSG00000109929 ENSG00000148377 PMC3171365__F2 Bayesian network fits for mutation data for cycle checkpoint II pathway using (a) Minimum Spanning Tree algorithm (maximum indegree of 1); (b) Bayesian Information Criterion (maximum indegree of 2) ENSG00000175054 ENSG00000138764 ENSG00000101773 ENSG00000099804 ENSG00000139687 ENSG00000175305 PMC3171365__F3 Bayesian network fits for wildtype data for cycle checkpoint II pathway using (a) Minimum Spanning Tree algorithm (maximum indegree of 1) ENSG00000175054 ENSG00000138764 ENSG00000101773 ENSG00000099804 ENSG00000139687 ENSG00000175305 PMC5807685__F1 Canonical hippo signaling pathway ENSG00000126016 ENSG00000114978 ENSG00000150457 ENSG00000132849 ENSG00000131023 PMC9099564__F2 Glioma Stem Cells in Pediatric High-Grade Gliomas: From Current Knowledge to Future Perspectives ENSG00000105894 ENSG00000168283 ENSG00000113140 ENSG00000198793 ENSG00000163914 ENSG00000026508 ENSG00000205927 PMC6802183__F7 Model structure consists of HIF-1A signaling, tumor signaling, and ATP depletion modules ENSG00000138798 ENSG00000146648 ENSG00000196712 PMC8352569__F3 DNA Methylation of PGC-1A Is Associated With Elevated mtDNA Copy Number and Altered Urinary Metabolites in Autism Spectrum Disorder ENSG00000116688 ENSG00000165283 ENSG00000106459 ENSG00000214253 PMC8010885__F6 Cholesterol associated changes in cancer cells and available therapeutic targets ENSG00000130164 ENSG00000015520 ENSG00000160179 PMC10758146__F1 Lithium exerts neuroprotective effects in ischemic stroke through multiple mechanisms ENSG00000162711 ENSG00000198793 ENSG00000168036 PMC7597592__F9 Proposed model of how TNFA and RIPK3 induce KC death following PH ENSG00000108691 ENSG00000137275 ENSG00000168040 ENSG00000285379 PMC2918404__F8 Osteogenic Transcription Factor Runx2 Regulates Components of the Fibroblast Growth Factor/Proteoglycan Signaling Axis in Osteoblasts ENSG00000077782 PMC3555197__F1 LXRs and prostate physiology: potential beneficial actions of LXRs over prostate cancer ENSG00000138075 ENSG00000002330 ENSG00000130164 ENSG00000160179 ENSG00000143921 PMC11899595__F1 Key molecular mechanisms/rationales for targeted agents in mantle cell lymphoma (MCL) ENSG00000105369 ENSG00000107562 ENSG00000161405 ENSG00000198793 ENSG00000171791 ENSG00000113851 ENSG00000010671 ENSG00000121966 PMC3567093__F6 Somatostatin Derivative (smsDX) Targets Cellular Metabolism in Prostate Cancer Cells after Androgen Deprivation Therapy ENSG00000074800 ENSG00000120437 PMC6695833__F1 YAP1/Hippo and wild-type p53 pathways coordinately maintain genomic stability in response to stress ENSG00000150457 ENSG00000131023 PMC6695833__F2 Transcriptional co-ordination between YAP1/Hippo and p53 family proteins in tumorigenesis or apoptosis ENSG00000113645 ENSG00000134057 ENSG00000120471 ENSG00000136518 ENSG00000140464 PMC7582405__F5 Most significant IPA networks involving the proteins that were differentially regulated between the CF and control states ENSG00000110244 ENSG00000117601 PMC5486846__F1 The extrinsic and intrinsic apoptotic pathways, as well as the inhibitory effect of various IAPs on pro-apoptotic molecules ENSG00000102871 ENSG00000168040 ENSG00000276068 PMC8318865__F7 Expression characteristics of interferon-stimulated genes and possible regulatory mechanisms in lupus patients using transcriptomics analyses ENSG00000174125 ENSG00000213928 ENSG00000188313 ENSG00000115415 ENSG00000115267 ENSG00000185885 ENSG00000172936 ENSG00000136869 ENSG00000276561 ENSG00000142166 PMC8576660__F2 Narrative review of emerging roles for AKT-mTOR signaling in cancer radioimmunotherapy ENSG00000291971 ENSG00000106070 ENSG00000136997 ENSG00000168610 PMC12197781__F6 Effect of Ad14 miRNAs on the NFKB signaling pathway ENSG00000166167 ENSG00000291603 ENSG00000048462 ENSG00000138798 ENSG00000196591 ENSG00000173039 ENSG00000213341 ENSG00000168040 ENSG00000150455 ENSG00000127191 ENSG00000183735 ENSG00000226275 ENSG00000244687 ENSG00000118503 ENSG00000082512 ENSG00000197943 ENSG00000157625 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000064012 ENSG00000198286 PMC9180607__F5 Molecular and Genetic Interactions between CCN2 and CCN3 behind Their Yin–Yang Collaboration ENSG00000136999 ENSG00000288283 ENSG00000185591 ENSG00000159399 PMC8624704__F5 Long-Term Effects of Ionizing Radiation on the Hippocampus: Linking Effects of the Sonic Hedgehog Pathway Activation with Radiation Response ENSG00000105894 ENSG00000007168 ENSG00000163739 ENSG00000164690 PMC4412127__F1 Signaling pathway regulation of ΔNp63 ENSG00000066468 ENSG00000106571 ENSG00000168036 ENSG00000168610 ENSG00000146648 ENSG00000276561 PMC4551923__F8 Rad4–Rad23 and GG-NER E3 ligase function in DDR signalling and dNTP synthesis PMC7291293__F3 Summary of caveolae/CAV-1 in signal transduction during virus infection ENSG00000291971 PMC8507004__F7 Promotion of chemerin in rat diabetic kidney disease through enhancement of TGFB1/Smads/CTGF pathway PMC4112878__F1 Endoplasmatic reticulum stress caused by saturated free fatty acids ENSG00000100290 ENSG00000002330 PMC4506078__F4 Adaptation of a Bioinformatics Microarray Analysis Workflow for a Toxicogenomic Study in Rainbow Trout ENSG00000066923 ENSG00000002330 ENSG00000082175 ENSG00000213658 ENSG00000135446 ENSG00000132646 ENSG00000285007 ENSG00000135336 ENSG00000105810 ENSG00000277273 ENSG00000117399 ENSG00000276876 PMC5077201__F6 Possible model of TIPE2 inhibition of activation of TAK1 signaling ENSG00000175104 ENSG00000127191 PMC7650600__F8 KIR2DL2/L3/S2+ CD8+ T cell cluster analysis of the protein-protein interaction (PPI) network with STRING database ENSG00000265681 ENSG00000116663 ENSG00000109332 ENSG00000183625 ENSG00000109906 ENSG00000020633 ENSG00000147604 ENSG00000138326 ENSG00000180644 ENSG00000169032 ENSG00000107829 ENSG00000136942 ENSG00000124762 ENSG00000116815 ENSG00000104131 ENSG00000088305 ENSG00000162244 ENSG00000126883 ENSG00000177954 ENSG00000276833 ENSG00000145592 ENSG00000276561 ENSG00000130255 ENSG00000203747 ENSG00000143156 ENSG00000272047 ENSG00000111537 ENSG00000224320 ENSG00000131398 ENSG00000274412 ENSG00000122223 ENSG00000174233 ENSG00000241343 ENSG00000015285 ENSG00000026508 ENSG00000146648 ENSG00000028137 PMC9271773__F2 Targeting Adenylate Cyclase Family: New Concept of Targeted Cancer Therapy ENSG00000149311 ENSG00000168036 ENSG00000160293 PMC9002106__F3 Pulmonary Inflammatory Response in Lethal COVID-19 Reveals Potential Therapeutic Targets and Drugs in Phases III/IV Clinical Trials ENSG00000162711 ENSG00000121058 PMC5154531__F6 Mice with an N-Ethyl-N-Nitrosourea (ENU) Induced Tyr209Asn Mutation in Natriuretic Peptide Receptor 3 (NPR3) Provide a Model for Kyphosis Associated with Activation of the MAPK Signaling Pathway ENSG00000173786 ENSG00000159899 PMC7697003__F4 FAK involvement in rhabdomyosarcoma ENSG00000019991 ENSG00000291971 ENSG00000198793 PMC9271773__F5 Targeting Adenylate Cyclase Family: New Concept of Targeted Cancer Therapy ENSG00000136997 ENSG00000077463 ENSG00000146648 PMC4943290__F1 Agents acting on the renin–angiotensin system pathway ©PharmGKB ENSG00000105329 ENSG00000100448 ENSG00000196549 ENSG00000130234 ENSG00000180772 ENSG00000143839 ENSG00000182220 ENSG00000168398 ENSG00000100739 PMC4877005__F3 Changes in the Adult GluN2B Associated Proteome following Adolescent Intermittent Ethanol Exposure ENSG00000145362 ENSG00000067842 ENSG00000176884 ENSG00000164061 ENSG00000186472 ENSG00000070961 ENSG00000058668 ENSG00000102003 ENSG00000197694 PMC9096244__F2 Review: PI3K/AKT/mTOR Signaling Pathway and Its Regulated Eukaryotic Translation Initiation Factors May Be a Potential Therapeutic Target in Esophageal Squamous Cell Carcinoma ENSG00000129474 ENSG00000198793 ENSG00000146648 ENSG00000109670 PMC9096244__F3 Review: PI3K/AKT/mTOR Signaling Pathway and Its Regulated Eukaryotic Translation Initiation Factors May Be a Potential Therapeutic Target in Esophageal Squamous Cell Carcinoma ENSG00000002330 ENSG00000169047 ENSG00000198793 ENSG00000164327 PMC4951461__F2 Metabolic Pathway Signatures Associated with Urinary Metabolite Biomarkers Differentiate Bladder Cancer Patients from Healthy Controls ENSG00000129167 ENSG00000095321 PMC2668232__F5 Principles in TLR signaling ENSG00000183735 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC1963413__F1 Oval of iNOS-inducing signaling pathways ENSG00000105402 ENSG00000142224 ENSG00000164342 PMC3572009__F5 Dysfunctional Activation of Neurotensin/IL-8 Pathway in Hepatocellular Carcinoma Is Associated with Increased Inflammatory Response in Microenvironment, More Epithelial Mesenchymal Transition in Cancer and Worse Prognosis in Patients ENSG00000113889 ENSG00000009724 ENSG00000275718 ENSG00000041982 ENSG00000164761 ENSG00000291998 ENSG00000163739 ENSG00000116741 ENSG00000164171 ENSG00000115009 ENSG00000137801 PMC9263829__F1 Can the cGAS-STING Pathway Play a Role in the Dry Eye? ENSG00000125538 ENSG00000162692 PMC3694976__F10 Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia ENSG00000110395 ENSG00000137193 PMC4877005__F2 Changes in the Adult GluN2B Associated Proteome following Adolescent Intermittent Ethanol Exposure ENSG00000145362 ENSG00000082397 ENSG00000100285 ENSG00000077522 ENSG00000178209 ENSG00000173786 ENSG00000149294 ENSG00000165280 ENSG00000197694 ENSG00000173898 ENSG00000183020 ENSG00000130402 ENSG00000072110 PMC4593313__F1 Cellular interactions in normal and diseased vasculature ENSG00000118972 ENSG00000066468 ENSG00000162692 ENSG00000077782 PMC204456__F5 Activated EGL-15 FGF receptor promotes protein degradation in muscles of Caenorhabditis elegans ENSG00000138433 ENSG00000173706 ENSG00000146648 PMC6887797__F1 TSC2 mediated crosstalk between the Akt/mTOR pathway and the cyclin D1-CDK4/6 axis.The cyclinD1/CDK4/6 axis is responsible for increased phosphorylation TSC2 and TSC1, and promotes the phosphorylation of the mTOR substrates, 4E-BP1 and S6K1 ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000146648 PMC10845928__F1 Immunologic properties of cancer stem cells (CSCs) ENSG00000130724 ENSG00000108691 ENSG00000125398 ENSG00000198053 ENSG00000101255 ENSG00000198793 ENSG00000232326 ENSG00000184371 ENSG00000168036 ENSG00000168610 ENSG00000196628 ENSG00000159399 PMC10845928__F2 Ferroptosis in CSCs ENSG00000168003 ENSG00000081041 ENSG00000151012 ENSG00000167468 ENSG00000164647 ENSG00000121966 PMC10845928__F3 Mechanisms underlying radio-resistance in CSCs ENSG00000149311 ENSG00000175054 ENSG00000126775 ENSG00000123374 ENSG00000051180 ENSG00000118971 ENSG00000168610 PMC10845928__F4 Mechanisms underlying chemoresistance in lung CSCs ENSG00000168283 ENSG00000001167 ENSG00000148400 ENSG00000149269 ENSG00000113356 ENSG00000114315 ENSG00000118777 PMC7352359__F3 Current model of regulating the BRI1 abundance on the plasma membrane (PM) ENSG00000028528 PMC3474103__F22 Diagram demonstrating the sites and mechanism of action of novel agents for the management of pancreatic endocrine neoplasm ENSG00000198793 ENSG00000146648 PMC7232103__F1 Proposed mechanism for the synthesis of dihydroindoles from triazole 1a and rationalization of dihydroindole regioselectivity from sigmatropic rearrangements PMC4043921__F4 Cytoskeletal proteins in cerebral cavernous malformation signaling pathways ENSG00000099985 ENSG00000198742 ENSG00000198793 ENSG00000100345 ENSG00000114209 PMC8560953__F7 Genetic and physical interactions between Polη and Rev1 in response to UV-induced DNA damage in mammalian cells ENSG00000132646 ENSG00000070950 ENSG00000130997 PMC4784227__F4 Heme biosynthesis pathway ENSG00000144410 ENSG00000126088 ENSG00000188690 PMC7072620__F1 HMGB1/RAGE and HMGB1/TLR4 signaling pathways in AD: HMGB1 can interact with extracellular AB peptides and decrease AB deposition by inhibiting AB clearance by microglia, as well as increasing Beta- and Gamma-secretase activity ENSG00000125538 ENSG00000087085 ENSG00000189403 PMC10838448__F2 RANKL/RANK signaling pathway activates NFATc1 ENSG00000231247 ENSG00000138772 ENSG00000235568 ENSG00000175104 ENSG00000131196 PMC368161__F7 Interaction Networks in Yeast Define and Enumerate the Signaling Steps of the Vertebrate Aryl Hydrocarbon Receptor ENSG00000006712 ENSG00000151239 ENSG00000284194 ENSG00000106546 PMC5354690__F1 FoxO1: a novel insight into its molecular mechanisms in the regulation of skeletal muscle differentiation and fiber type specification ENSG00000148400 ENSG00000198793 ENSG00000163914 ENSG00000081189 PMC9710321__F1 Cannabis sativa and Cannabidiol: A Therapeutic Strategy for the Treatment of Neurodegenerative Diseases? ENSG00000134982 ENSG00000168610 ENSG00000196689 PMC9710321__F2 Cannabis sativa and Cannabidiol: A Therapeutic Strategy for the Treatment of Neurodegenerative Diseases? ENSG00000134982 ENSG00000196689 PMC6398583__F3 Control of aerobic glycolysis by ERK and JNK signaling pathways in proliferating cells ENSG00000157764 ENSG00000136997 PMC6398583__F4 ERK- and JNK-mediated phosphorylation of PKM2 is at the crossroad between proliferation and apoptosis ENSG00000127445 ENSG00000138798 PMC4985055__F2 BMP signaling in bone ENSG00000170365 ENSG00000137834 ENSG00000198742 PMC4985055__F1 TGFB signaling in bone PMC7061838__F5 Relationships between GRHL2 and TGFB/MAPK signal pathways PMC6618030__F5 A suggested relationship between the defatting cocktail and intracellular lipolytic metabolic pathways ENSG00000161533 ENSG00000026103 PMC8591115__F7 KRAS mutation: from undruggable to druggable in cancer ENSG00000169047 ENSG00000198793 PMC8861005__F7 Antidiabetic activity of avocado seeds (Persea americana Mill.) in diabetic rats via activation of PI3K/AKT signaling pathway ENSG00000042832 ENSG00000132646 ENSG00000169047 ENSG00000171791 PMC8591115__F2 KRAS mutation: from undruggable to druggable in cancer ENSG00000183735 ENSG00000002330 ENSG00000070831 ENSG00000156299 ENSG00000138798 ENSG00000198793 PMC7664983__F1 Action of Statins and Potential Interactions with Estrogen PMC11211395__F3 Dual role of sirtuins in cancer: biological functions and implications ENSG00000143799 ENSG00000175054 ENSG00000165392 ENSG00000139372 ENSG00000077463 ENSG00000096717 ENSG00000136936 PMC6874216__F1 The biosynthetic pathway of ubiquinone (Q) in E ENSG00000132423 ENSG00000119723 ENSG00000110871 ENSG00000197429 ENSG00000173085 ENSG00000167186 PMC4899530__F14 Mechanism of Nrf2 activation by DMF and MMF and its role in neuroprotection ENSG00000178573 ENSG00000156273 ENSG00000079999 PMC11211395__F2 Dual role of sirtuins in cancer: biological functions and implications ENSG00000134419 ENSG00000072274 ENSG00000136997 ENSG00000077463 ENSG00000142082 ENSG00000089163 PMC3481038__F2 Scheme demonstrating mechanisms used by natural compounds to drive changes in the epigenome ENSG00000132646 PMC7224341__F1 Compartmentalization of adenosine biochemistry ENSG00000196839 ENSG00000291814 PMC3225948__F7 Three arms of the unfolded protein response stress-responsive signaling pathway ENSG00000128272 ENSG00000100219 PMC2797439__F1 Class IA PI3K signalling pathway ENSG00000124102 ENSG00000198793 ENSG00000217128 PMC4964535__F1 Mechanism and pathway map of the prostate cancer (modified based on KEGG database) ENSG00000019991 ENSG00000002330 ENSG00000026508 ENSG00000123374 ENSG00000171791 ENSG00000111816 PMC6138501__F1 Inflammasome activation and purinergic signaling in Chlamydia-infected cells ENSG00000125538 ENSG00000136869 PMC9144571__F2 Whole Aspect of Runx2 Functions in Skeletal Development ENSG00000029559 ENSG00000242252 ENSG00000118785 ENSG00000291837 ENSG00000108821 PMC9406852__F1 Transcriptome Profiling Reveals Differential Expression of Circadian Behavior Genes in Peripheral Blood of Monozygotic Twins Discordant for Parkinson’s Disease ENSG00000180758 PMC11598538__F3 Metabolites and DEGs in the biosynthesis pathways of fatty acid derivative and terpenoid in Oncidium Twinkle ‘Red Fantasy’ ENSG00000110921 ENSG00000197429 PMC2826542__F1 An Overview of IL-7 Biology and Its Use in Immunotherapy PMC2738133__F3 Molecular Aspects of Moraxella catarrhalis Pathogenesis ENSG00000236625 PMC5932236__F4 Pan-cancer molecular classes transcending tumor lineage across 32 cancer types, multiple data platforms, and over 10,000 cases ENSG00000151726 ENSG00000135547 ENSG00000125735 ENSG00000134982 ENSG00000163599 ENSG00000169710 ENSG00000163541 ENSG00000157184 ENSG00000089692 ENSG00000065833 ENSG00000128917 ENSG00000074181 ENSG00000069812 ENSG00000173599 ENSG00000146701 ENSG00000062485 ENSG00000148400 ENSG00000188389 ENSG00000101365 ENSG00000186827 ENSG00000197461 ENSG00000124216 ENSG00000172840 ENSG00000090857 ENSG00000115361 ENSG00000067992 ENSG00000117118 ENSG00000168036 ENSG00000112992 ENSG00000112715 ENSG00000100412 ENSG00000091140 ENSG00000131473 ENSG00000039537 ENSG00000275385 ENSG00000116044 ENSG00000005882 ENSG00000147381 ENSG00000129226 ENSG00000105953 ENSG00000184916 ENSG00000172340 ENSG00000135144 ENSG00000131828 ENSG00000090932 ENSG00000079999 ENSG00000143252 ENSG00000108691 ENSG00000163114 ENSG00000117091 ENSG00000122223 ENSG00000156427 ENSG00000184371 ENSG00000197142 ENSG00000049249 ENSG00000100985 ENSG00000164398 ENSG00000268651 ENSG00000114315 ENSG00000181433 PMC6367587__F9 Schematic map describing apoptosis induction of the TRAIL and Andro combination therapy ENSG00000168040 PMC3693544__F1 Transcriptional feedback in the insulin signalling pathway modulates ageing ENSG00000118515 ENSG00000125686 ENSG00000160691 PMC3693544__F2 Transcriptional feedback in the insulin signalling pathway modulates ageing ENSG00000284161 ENSG00000170145 ENSG00000096088 ENSG00000168036 ENSG00000164327 ENSG00000198670 ENSG00000166278 PMC8645722__F8 G protein pathway suppressor 2 suppresses gastric cancer by destabilizing epidermal growth factor receptor ENSG00000110395 ENSG00000138798 ENSG00000198793 ENSG00000288325 ENSG00000146648 PMC5390339__F1 Canonical Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4850838__F2 Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease ENSG00000167772 PMC9697024__F8 Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway ENSG00000168610 PMC7440669__F2 In silico co-factor balance estimation using constraint-based modelling informs metabolic engineering in Escherichia coli ENSG00000065833 ENSG00000166816 ENSG00000082212 PMC3102743__F7 Nodal-Dependent Mesendoderm Specification Requires the Combinatorial Activities of FoxH1 and Eomesodermin ENSG00000160973 ENSG00000164736 ENSG00000156574 PMC3674720__F1 The insulin-signaling pathway ENSG00000002330 ENSG00000101255 ENSG00000010810 ENSG00000169047 ENSG00000198793 PMC8085803__F2 Immunoceptive inference: why are psychiatric disorders and immune responses intertwined? ENSG00000111537 PMC4931134__F1 Disruption of miRNA biogenesis by estrogens and cigarette smoke can lead to oncogenesis ENSG00000136997 ENSG00000146648 ENSG00000113360 PMC11012149__F2 Necrosis Links Neurodegeneration and Neuroinflammation in Neurodegenerative Disease ENSG00000110711 ENSG00000162711 ENSG00000102871 ENSG00000163568 ENSG00000091592 ENSG00000091106 ENSG00000168040 ENSG00000197451 ENSG00000197386 ENSG00000189403 ENSG00000136869 ENSG00000168404 ENSG00000140443 ENSG00000026103 ENSG00000084774 PMC3891052__F3 Cumulative Haploinsufficiency and Triplosensitivity Drive Aneuploidy Patterns to Shape the Cancer Genome ENSG00000142178 ENSG00000134982 ENSG00000291971 ENSG00000198793 ENSG00000121067 ENSG00000116251 ENSG00000146733 ENSG00000196396 ENSG00000175054 ENSG00000134086 ENSG00000186575 ENSG00000159216 ENSG00000163558 ENSG00000136997 ENSG00000150907 ENSG00000277263 ENSG00000196712 ENSG00000196367 ENSG00000026103 ENSG00000063978 ENSG00000157764 ENSG00000168040 ENSG00000127191 ENSG00000087460 ENSG00000183337 ENSG00000107485 ENSG00000164690 ENSG00000128602 ENSG00000146648 ENSG00000137948 ENSG00000111642 PMC6929403__F2 The ceRNA networks involved in the chemokine signaling pathway ENSG00000169245 ENSG00000081041 ENSG00000138755 ENSG00000163734 ENSG00000163736 ENSG00000127588 ENSG00000163737 PMC4969098__F3 Actions of IL-21 on T cells are context-dependent and shaped by cellular and environmental parameters ENSG00000138378 ENSG00000115415 ENSG00000198793 ENSG00000137265 ENSG00000168610 PMC9021453__F6 Regularity of Toll-Like Receptors in Bovine Mammary Epithelial Cells Induced by Mycoplasma bovis ENSG00000172936 ENSG00000276561 PMC5019180__F2 Complement-mediated regulation of metabolism and basic cellular processes ENSG00000009724 ENSG00000198793 ENSG00000117335 ENSG00000171791 ENSG00000182326 ENSG00000236625 PMC2651433__F2 A nuclear SIRT1 mechanism for delaying NAD-ATP depletion through inhibition of PARP-1 is presented ENSG00000105835 ENSG00000173614 ENSG00000096717 PMC7600363__F2 Biosynthesis and major signalling pathways activated by FLT3 wildtype (WT) (a) and FLT3 with internal tandem duplication (ITD) mutation (b) ENSG00000122025 ENSG00000086991 PMC6357151__F5 Differential Transcriptome Responses to Aflatoxin B1 in the Cecal Tonsil of Susceptible and Resistant Turkeys ENSG00000162009 ENSG00000159224 ENSG00000069482 ENSG00000146469 ENSG00000163394 ENSG00000291631 ENSG00000131096 ENSG00000157005 ENSG00000010310 ENSG00000185149 PMC2651433__F4 The Importance of NAD in Multiple Sclerosis ENSG00000143799 ENSG00000187531 ENSG00000291803 ENSG00000077463 ENSG00000138617 ENSG00000142082 ENSG00000178685 ENSG00000173200 ENSG00000137817 ENSG00000283100 ENSG00000151883 ENSG00000111537 ENSG00000102699 ENSG00000059378 ENSG00000041880 ENSG00000124523 ENSG00000096717 ENSG00000089163 ENSG00000227345 ENSG00000111224 PMC6518944__F3 Metabolic dysregulation in GC‐derived B‐cell lymphoma ENSG00000198793 ENSG00000136997 ENSG00000196092 ENSG00000142082 PMC6518944__F4 Aberrant BCR signaling in GC‐derived B‐cell lymphomas ENSG00000122986 ENSG00000104365 ENSG00000105369 ENSG00000100906 ENSG00000007312 ENSG00000198793 ENSG00000269335 ENSG00000010671 ENSG00000071564 ENSG00000177455 ENSG00000095585 ENSG00000239732 ENSG00000118503 ENSG00000186716 ENSG00000172936 ENSG00000283060 ENSG00000175104 ENSG00000184216 ENSG00000198286 PMC6797793__F1 A schematic of the tanshinone biosynthetic pathway ENSG00000197429 PMC8556920__F1 Insulin-like growth factor-1 in articular cartilage repair for osteoarthritis treatment ENSG00000198793 ENSG00000140443 PMC5945668__F3 Contraction of smooth muscle cell: cellular pathway and the role of MYL9 and of other genes related to MMIHS ENSG00000163914 PMC7831272__F7 Proposed model on the epigenetic regulation mechanisms of histone H3K27 acetylation causing the FLHS in laying hens ENSG00000157404 ENSG00000167772 ENSG00000140285 PMC3328452__F8 Identification of Protein Networks Involved in the Disease Course of Experimental Autoimmune Encephalomyelitis, an Animal Model of Multiple Sclerosis ENSG00000115091 ENSG00000125814 ENSG00000142192 ENSG00000074800 ENSG00000100285 ENSG00000167552 ENSG00000105402 ENSG00000156113 PMC3671248__F7 Model for 20E regulation of IMD innate immune signalling ENSG00000168040 ENSG00000143196 PMC9002353__F7 mTOR Signaling Pathway Regulates the Release of Proinflammatory Molecule CCL5 Implicated in the Pathogenesis of Autism Spectrum Disorder ENSG00000005339 ENSG00000198793 PMC4529006__F1 Genes within the BDNF signaling pathway [adapted with permission from Macmillan Publishers Ltd ENSG00000140992 ENSG00000152495 ENSG00000008056 PMC10875059__F1 Metabolic pathway of risperidone PMC5653411__F1 Apoptosis and necroptosis as host defense strategies to prevent viral infection ENSG00000164430 ENSG00000088888 ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000285379 ENSG00000164342 PMC8927965__F2 Dysregulation of Survivin-Targeting microRNAs in Autoimmune Diseases: New Perspectives for Novel Therapies ENSG00000124102 ENSG00000163935 ENSG00000112242 ENSG00000105329 ENSG00000168610 PMC10875059__F3 Pharmacogenomics and non-genetic factors affecting drug response in autism spectrum disorder in Thai and other populations: current evidence and future implications PMC6696086__F5 Signaling pathway regulating pluripotency of stem cells is modified during neural differentiation ENSG00000162552 ENSG00000115266 ENSG00000188763 ENSG00000136826 PMC6363687__F4 FGFR1 pathway promotes NFKB signaling ENSG00000102871 ENSG00000157625 ENSG00000077782 PMC2395193__F3 Gene networks identified in both recEbo-VP35/WT- and recEbo-VP35/R312A-infected cells compared to mock-infected and irradiated controls ENSG00000068028 ENSG00000169908 ENSG00000092201 ENSG00000074800 ENSG00000049130 ENSG00000044115 ENSG00000141562 ENSG00000170571 PMC6412296__F1 Intrinsic and extrinsic apoptotic signalling pathways and points of therapeutic intervention ENSG00000168040 PMC11476647__F1 Nrf2/Keap1/ARE signaling pathway ENSG00000084093 ENSG00000104221 ENSG00000079999 PMC3775564__F5 Molecular network analysis of the miR-200 family and potential molecular targets with Ingenuity pathway analysis (IPA) ENSG00000168283 ENSG00000169554 ENSG00000010704 ENSG00000106327 ENSG00000072274 ENSG00000205250 ENSG00000273686 PMC3089921__F1 mTOR activation supports cancer cell survival ENSG00000213658 ENSG00000198793 PMC6993271__F1 Actions of metformin in eukaryotic cells ENSG00000198793 ENSG00000162772 ENSG00000168610 PMC11476647__F2 Pathways influencing Nrf2 build-up and its downstream pathways ENSG00000145321 ENSG00000247077 ENSG00000079999 PMC7026856__F1 [U-13C6]-glucose metabolism in the brain ENSG00000159224 ENSG00000122966 ENSG00000172005 PMC7581685__F2 Part of the innate immune signaling pathways triggered after the viral RNA is recognized by TLRs and RLRs ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC9684661__F2 Immunometabolism in the pathogenesis of vitiligo ENSG00000169245 ENSG00000186810 ENSG00000115415 ENSG00000138755 PMC5137695__F5 Summary model of Tri-DAP activity and pathway utilization in HCMV-infected cells ENSG00000183735 ENSG00000106100 PMC9684661__F1 Immunometabolism in the pathogenesis of vitiligo ENSG00000169245 ENSG00000161921 ENSG00000138755 PMC4013640__F2 Pericyte physical and biochemical interactions at the NVU ENSG00000170558 PMC7279287__F1 Synthesis of butyrate in E ENSG00000026103 PMC2845642__F2 Molecular Mechanisms of T cell Receptor and Costimulatory Molecule Ligation/Blockade in Autoimmune Disease Therapy ENSG00000213658 PMC3672773__F1 Schematic presentation of select miRNAs that regulate toll-like receptor signaling pathways ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC1698636__F6 F igure 6.— ENSG00000099804 PMC151039__F1 The classical pathway for bile acid synthesis begins with CYP7A1, which converts cholesterol into 7Alpha-hydroxycholesterol ENSG00000167910 PMC3863339__F1 RACK1 signaling complexes ENSG00000291971 PMC3286973__F2 Cell-line subtypes have unique SuperPathway network features ENSG00000128016 ENSG00000152495 ENSG00000050748 ENSG00000060982 ENSG00000160182 ENSG00000168036 ENSG00000169032 ENSG00000118971 ENSG00000161960 ENSG00000241878 ENSG00000145604 ENSG00000112242 ENSG00000038427 ENSG00000135446 ENSG00000136997 ENSG00000115263 ENSG00000100219 ENSG00000164690 ENSG00000095002 ENSG00000168495 PMC3286973__F3 Pathway diagrams can be used to predict response to therapies ENSG00000149311 ENSG00000065361 ENSG00000124882 ENSG00000138794 ENSG00000116717 ENSG00000173846 ENSG00000149554 ENSG00000178568 ENSG00000026103 ENSG00000183765 PMC11064802__F7 Action of carbohydrates in atherosclerosis therapy ENSG00000138075 ENSG00000198793 ENSG00000015520 ENSG00000172936 ENSG00000143921 PMC11064802__F1 Action of TCM prescriptions and natural bioactive molecules in atherosclerosis therapy by targeting peroxisome proliferator-activated receptors (PPARs) ENSG00000135218 ENSG00000161533 ENSG00000172936 ENSG00000136869 ENSG00000160179 PMC4831128__F6 Ingenuity Pathway Analysis (IPA) of cholesterol and bile acid metabolism genes ENSG00000141458 ENSG00000160179 ENSG00000132170 PMC3186046__F1 S1P receptor subtype-specific heterotrimeric G protein coupling and intracellular signaling mechanisms ENSG00000163914 ENSG00000170989 ENSG00000213694 ENSG00000267534 PMC9519310__F7 Interaction of the IFNG/JAK/STAT1 and JAK/STAT3 Signalling Pathways in EGFR-Mutated Lung Adenocarcinoma Cells ENSG00000115415 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC2654418__F6 Crosstalk between the Androgen Receptor and Beta-Catenin in Castrate Resistant Prostate Cancer ENSG00000071564 ENSG00000138795 ENSG00000178585 ENSG00000136997 ENSG00000168036 ENSG00000176105 ENSG00000196628 PMC8520212__F5 The tumor microbe microenvironment in the tumor immune microenvironment: bystander, activator, or inhibitor? ENSG00000198053 ENSG00000181847 PMC2663816__F1 Single-Cell Profiling Reveals the Origin of Phenotypic Variability in Adipogenesis ENSG00000102104 PMC12150179__F2 Influence of ROS induced by microplastics on macrophage metabolism, function, and polarization ENSG00000278718 ENSG00000149311 ENSG00000177575 ENSG00000162711 ENSG00000108691 ENSG00000164430 ENSG00000135218 ENSG00000167468 ENSG00000198793 ENSG00000072274 ENSG00000285379 ENSG00000007171 PMC12150179__F3 Microplastics indirectly affect macrophages by disrupting gut microbiota ENSG00000108691 ENSG00000136869 PMC8470673__F1 High-Fat Diets Modify the Proteolytic Activities of Dipeptidyl-Peptidase IV and the Regulatory Enzymes of the Renin–Angiotensin System in Cardiovascular Tissues of Adult Wistar Rats ENSG00000130234 ENSG00000196839 ENSG00000178922 PMC5104457__F1 ATP-Competitive MLKL Binders Have No Functional Impact on Necroptosis ENSG00000108582 ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC5354977__F1 Interplay between immune checkpoint proteins and cellular metabolism ENSG00000163599 ENSG00000198793 PMC5292326__F1 Functions of natural IgM in homeostasis maintenance and autoimmune diseases prevention; (A) sIgM enhances apoptotic cell clearance ENSG00000110448 ENSG00000186716 PMC8615588__F1 Expanding the Disorder-Function Paradigm in the C-Terminal Tails of Erbbs ENSG00000122882 ENSG00000065361 ENSG00000163235 ENSG00000138798 ENSG00000158458 ENSG00000146648 ENSG00000169752 ENSG00000178568 PMC6753603__F2 Schematic overview of the two most common pathways with genetic alterations in thyroid cancer—mitogen-activated protein kinase (MAPK) and phosphatidylinositide 3-kinase (PI3K) pathways ENSG00000066468 ENSG00000198793 ENSG00000077782 ENSG00000196712 PMC8256363__F9 Novel lncRNA promotes myogenesis of bovine skeletal muscle satellite cells via PFN1‐RhoA/Rac1 ENSG00000168036 ENSG00000108518 PMC5293166__F4 Targeting PI3K in cancer: impact on tumor cells, their protective stroma, angiogenesis and immunotherapy ENSG00000111537 ENSG00000150907 ENSG00000188404 ENSG00000126353 ENSG00000166278 ENSG00000112182 ENSG00000049768 PMC9465037__F2 Bacterial cyclic di-adenosine monophosphate in the host immune response ENSG00000162711 PMC10706706__F6 DEGs expression pattern diagram of JA biosynthetic pathway in mustard leaves after beet armyworm larvae chewing ENSG00000131480 PMC6450927__F10 Nrf2 signaling and autophagy are complementary in protecting lipopolysaccharide/d-galactosamine-induced acute liver injury by licochalcone A ENSG00000162711 ENSG00000172936 ENSG00000136869 ENSG00000265972 PMC6407289__F11 Model for Pyk2 action in AD risk ENSG00000010810 ENSG00000281879 PMC9520111__F2 TNFIFN-induced necroptosis ENSG00000124256 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000164305 ENSG00000285379 ENSG00000142166 PMC7555743__F7 Schematic diagram showing the signaling pathways involved in anti-inflammatory effects of the combination of ginsenosides Rg2 and Rh1 in macrophages ENSG00000115415 ENSG00000125538 ENSG00000136869 PMC8882979__F1 Noncanonical Wnt5a Signaling Suppresses Hippo/TAZ-Mediated Osteogenesis Partly Through the Canonical Wnt Pathway in SCAPs ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000185483 PMC5470107__F2 Interconnected processes of (i) S1P synthesis and degradation within the sphingomyelin/salvage pathway, (ii) S1P export and (iii) signaling through binding to five specific G-protein-coupled receptors, S1PR1-5 ENSG00000063176 ENSG00000118785 ENSG00000163914 ENSG00000170989 ENSG00000180739 ENSG00000213694 ENSG00000125910 ENSG00000267534 ENSG00000183018 ENSG00000072080 PMC5638182__F2 Mongersen, tofacitinib, filgotinib: mechanisms of action ENSG00000105639 PMC6265005__F1 Tumor necrosis factorA pathway for necroptosis ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC8127406__F7 Multi-OMICS study of a CHCHD10 variant causing ALS demonstrates metabolic rewiring and activation of endoplasmic reticulum and mitochondrial unfolded protein responses ENSG00000273607 ENSG00000105550 ENSG00000198793 ENSG00000106153 ENSG00000100219 ENSG00000125656 ENSG00000130513 ENSG00000115317 PMC8296533__F1 Antiangiogenic therapy reverses the immunosuppressive breast cancer microenvironment ENSG00000145431 ENSG00000151882 ENSG00000107562 ENSG00000162493 ENSG00000184371 PMC4677515__F1 Survey of the Impact of Deyolking on Biological Processes Covered by Shotgun Proteomic Analyses of Zebrafish Embryos ENSG00000108702 ENSG00000184060 ENSG00000143318 ENSG00000183576 ENSG00000148842 ENSG00000134308 ENSG00000163499 ENSG00000104450 ENSG00000175455 ENSG00000081277 ENSG00000176533 ENSG00000100122 ENSG00000096006 ENSG00000130935 ENSG00000171051 ENSG00000068976 ENSG00000162607 ENSG00000011143 ENSG00000116030 ENSG00000144061 ENSG00000146701 ENSG00000166341 ENSG00000151376 ENSG00000196296 ENSG00000078369 ENSG00000149357 ENSG00000010256 ENSG00000135480 ENSG00000083845 ENSG00000127483 ENSG00000133110 ENSG00000100302 ENSG00000102970 ENSG00000170477 ENSG00000115165 ENSG00000143553 ENSG00000102962 ENSG00000124875 ENSG00000150991 ENSG00000100412 ENSG00000126803 ENSG00000165458 ENSG00000170893 ENSG00000213999 ENSG00000189403 ENSG00000155657 ENSG00000106178 ENSG00000127928 ENSG00000116748 ENSG00000172243 ENSG00000177058 ENSG00000155876 ENSG00000114573 ENSG00000065609 ENSG00000174233 ENSG00000141367 PMC2629585__F7 Local Inflammation Induces Complement Crosstalk Which Amplifies the Antimicrobial Response ENSG00000288512 ENSG00000166278 ENSG00000132693 ENSG00000182326 PMC6355880__F8 Model describing the distinct fates of NK cells during NK cell education ENSG00000124102 ENSG00000115020 PMC7564754__F4 How selected polyphenols can interact with p57 expression and activity (see and text for details) ENSG00000129757 ENSG00000132646 PMC7278812__F3 Selenium-dependent antioxidant system of glutathione peroxidases (GPx) and thioredoxin reductases (TrxR) ENSG00000167468 PMC8101358__F1 Heritability and family-based GWAS analyses of the N-acyl ethanolamine and ceramide plasma lipidome ENSG00000100596 ENSG00000117480 ENSG00000143753 ENSG00000100439 ENSG00000285281 ENSG00000172296 ENSG00000006007 ENSG00000163082 PMC7564754__F3 Selected polyphenols that interfere with p27 expression and activity (see and text for details) ENSG00000291971 ENSG00000123374 PMC4940708__F8 Mechanism of the disease-modifying effect of P021 in AD ENSG00000142192 PMC6010716__F3 Genes predicted to increase cardiovascular angiogenesis are strongly up‐regulated by CpG pre‐conditioning 24 h post‐I/R ENSG00000169896 ENSG00000078747 PMC8204760__F3 Non-G-protein signaling at 5-HT receptors ENSG00000142192 ENSG00000070831 ENSG00000291971 PMC8204760__F4 Constitutive activation of 5-HT6 receptors by different GPCR-interacting proteins (GIPs) ENSG00000159224 ENSG00000070831 ENSG00000198793 ENSG00000196712 PMC9425441__F7 Vascular Endothelium and Coagulation: Homeostasis, Disease, and Treatment, with a Focus on the Von Willebrand Factor and Factors VIII and V ENSG00000281244 ENSG00000110799 ENSG00000173599 PMC4085546__F2 KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma ENSG00000100985 ENSG00000112715 ENSG00000128602 PMC8473645__F8 Glutathione peroxidase 4‐dependent glutathione high‐consumption drives acquired platinum chemoresistance in lung cancer‐derived brain metastasis ENSG00000167468 PMC6747935__F2 How insulin-stimulated cleavage of TUG and subsequent trafficking of GSVs coordinately regulates multiple physiologic effects ENSG00000169047 ENSG00000155313 PMC6370335__F2 Intercellular and intracellular signals that initiate liver regeneration ENSG00000019991 ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000125538 ENSG00000168610 PMC12026336__F1 RSV infection induces TLR signaling ENSG00000170458 ENSG00000136869 ENSG00000175104 PMC4256331__F11 The signaling pathways affected by Syk that drive AB production, neuroinflammation, and Tau hyperphosphorylation PMC7988780__F3 Is nuclear sirtuin SIRT6 a master regulator of immune function? ENSG00000136997 ENSG00000077463 ENSG00000115419 PMC3876437__F1 A non-canonical JAK-STAT pathway in IFN therapy of poxvirus infection and multiple sclerosis ENSG00000159128 ENSG00000027697 PMC5000752__F7 Simplified representation of canonical and non-canonical Hedgehog(HH) signaling ENSG00000106571 ENSG00000164161 ENSG00000198793 ENSG00000128602 PMC3000843__F1 Schematic representation of chiral 3HV production via the threonine biosynthesis pathway in metabolically engineered E PMC10520719__F11 ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer ENSG00000170365 ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000134595 ENSG00000155760 ENSG00000073670 PMC5000752__F6 Androgen receptor (AR) signaling pathway ENSG00000291971 PMC9682156__F1 Autophagy and the primary cilium in cell metabolism: What’s upstream? ENSG00000198793 ENSG00000166603 PMC2491599__F2 Wnt canonical signaling pathway ENSG00000156076 ENSG00000137673 ENSG00000134982 ENSG00000147869 ENSG00000177606 ENSG00000136997 PMC3415084__F2 Impact of placental insufficiency on endocrine responsiveness in fetal myoblasts and myofibers ENSG00000169047 PMC8307885__F2 Nano-Strategies Targeting the Integrin AvB3 Network for Cancer Therapy ENSG00000291971 ENSG00000168036 ENSG00000100211 ENSG00000086548 PMC2491599__F3 Wnt signaling pathwhay in cervical cancer ENSG00000087095 ENSG00000134982 ENSG00000104290 PMC5546324__F5A AKT/PKB Signaling: Navigating the Network ENSG00000145979 ENSG00000121058 PMC8995861__F3 Oxidative RNA Damage in the Pathogenesis and Treatment of Type 2 Diabetes ENSG00000165609 ENSG00000136159 ENSG00000275074 PMC9307784__F4 Orbital fibroblasts (OFs) in acute and chronic TED ENSG00000165409 ENSG00000140443 PMC8970309__F2 Overcome Drug Resistance in Cholangiocarcinoma: New Insight Into Mechanisms and Refining the Preclinical Experiment Models ENSG00000134982 ENSG00000118777 PMC3133937__F1 Concerted regulation of the WNT-DVL-GSK3B signaling pathway in NAc by chronic social defeat stress ENSG00000162552 ENSG00000274382 ENSG00000168036 ENSG00000168646 PMC8850271__F1 Emerging Role of Bile Acids in the Pathogenesis of Inflammatory Bowel Disease ENSG00000167910 ENSG00000115271 ENSG00000135929 PMC8850271__F2 Emerging Role of Bile Acids in the Pathogenesis of Inflammatory Bowel Disease ENSG00000160867 ENSG00000167910 PMC4493455__F2 Schematic overview of ligand-stimulated SR signal transduction ENSG00000135218 ENSG00000010810 ENSG00000213523 PMC8861487__F2 Innate Immunity in Natural Elite Controllers of HIV-1 Infection ENSG00000239732 ENSG00000164430 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC11915864__F9 RNF20 demonstrates dual regulation of the chicken MDA5-IFNB signaling pathway by targeting chMDA5 (created using Figdraw) ENSG00000183735 ENSG00000088888 ENSG00000155827 ENSG00000276561 PMC3986510__F1 Ceramide de novo synthesis pathway ENSG00000139624 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000143418 PMC3986510__F4 Diagram demonstrating sites of interference by various small molecule agents or genetic ablation of enzymes engaged in ceramide and sphingolipid synthesis pathway ENSG00000139624 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000143418 PMC6194161__F1 TLR and CLR interactions with helminth-derived products ENSG00000162711 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC8508851__F13 Mathematical Modelling of p53 Signalling during DNA Damage Response: A Survey ENSG00000149311 PMC3613056__F7 Pathway scheme of baicalein on the cell proliferation inhibition and cell metastasis inhibition in human bladder cancer cell 5637 ENSG00000087245 ENSG00000134057 ENSG00000100985 PMC3688269__F2 Dysfunctional telomeres activate upstream checkpoint PI3 kinases, such as ATM (ataxia-telangiectasia mutated) or ATR (ataxia-telangiectasia and Rad3 related), - () ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000105810 PMC3513735__F3 Most enriched molecular networks showing interactions between the significant genes (according to SAM)—(a) FOSB, ERK, MAPK3, CYR61, and the RAS-genes; (b) DUSP1, ERK1/2, P38MAPK, DUSP9, and RASD1; (c) CYR61 and NFRKB ENSG00000125740 ENSG00000145687 ENSG00000128016 ENSG00000143878 ENSG00000284984 ENSG00000050327 ENSG00000170322 ENSG00000067066 ENSG00000169291 ENSG00000160298 ENSG00000104140 ENSG00000145623 ENSG00000186716 ENSG00000071051 ENSG00000157514 ENSG00000150630 PMC5421758__F2 Identification of potential new treatment response markers and therapeutic targets using a Gaussian process-based method in lapatinib insensitive breast cancer models ENSG00000175206 ENSG00000124789 ENSG00000100842 ENSG00000129514 ENSG00000165516 ENSG00000130055 ENSG00000157227 ENSG00000117400 ENSG00000066044 ENSG00000140548 ENSG00000100241 ENSG00000163914 ENSG00000153046 ENSG00000090060 ENSG00000137776 ENSG00000117335 ENSG00000220205 ENSG00000168488 ENSG00000184575 ENSG00000143977 ENSG00000166167 ENSG00000103266 ENSG00000147162 ENSG00000198408 ENSG00000148400 ENSG00000005243 ENSG00000063244 ENSG00000130227 ENSG00000165282 ENSG00000115648 ENSG00000065518 ENSG00000130726 ENSG00000175221 ENSG00000115425 ENSG00000105254 ENSG00000138798 ENSG00000169032 ENSG00000105894 ENSG00000180957 ENSG00000197386 ENSG00000151914 ENSG00000106305 ENSG00000124422 ENSG00000060237 ENSG00000092199 ENSG00000087460 ENSG00000047056 ENSG00000090316 ENSG00000115415 ENSG00000122705 ENSG00000151239 ENSG00000130175 ENSG00000122678 PMC2711321__F2 Wiring diagrams for a three-module decomposition of the intrinsic apoptotic pathway ENSG00000113600 ENSG00000171791 PMC11240800__F2 Abnormal signaling pathways contribute to the pathogenesis of uLMS ENSG00000291971 ENSG00000128602 PMC7564554__F7 lncRNA–mRNA co–expression network ENSG00000259330 PMC6430781__F5 Sub-network of the innate signaling pathway obtained after IPA analysis of the differentially expressed genes in A549 lung epithelial cells infected with WM 06.482 conidia ENSG00000104856 ENSG00000128016 ENSG00000185022 ENSG00000186716 ENSG00000198517 ENSG00000062485 PMC4433221__F5 Variation in the Ovine Abomasal Lymph Node Transcriptome between Breeds Known to Differ in Resistance to the Gastrointestinal Nematode ENSG00000068079 ENSG00000213928 ENSG00000033800 ENSG00000125347 ENSG00000230034 PMC2267714__F3 Gene expression changes detected in selected pathways in M group ENSG00000175054 ENSG00000132646 ENSG00000140743 PMC4433221__F6 Variation in the Ovine Abomasal Lymph Node Transcriptome between Breeds Known to Differ in Resistance to the Gastrointestinal Nematode ENSG00000213928 ENSG00000134321 ENSG00000119888 ENSG00000197594 ENSG00000157601 ENSG00000160710 ENSG00000101425 ENSG00000182179 PMC9298548__F3 Comparative Transcriptome Analysis Reveals the Mechanism Associated With Dynamic Changes in Meat Quality of the Longissimus Thoracis Muscle in Tibetan Sheep at Different Growth Stages ENSG00000180210 ENSG00000171105 ENSG00000135218 ENSG00000005882 ENSG00000198793 ENSG00000001626 ENSG00000096717 ENSG00000026103 PMC6612360__F1 Endothelial dysfunction and angiogenesis impairment in the ageing vasculature ENSG00000198793 ENSG00000096717 ENSG00000111224 PMC7651862__F8 Our working model in this study ENSG00000108395 ENSG00000138795 ENSG00000137673 ENSG00000122691 ENSG00000026508 ENSG00000168036 ENSG00000196628 PMC5819357__F1 Combinatorial CRISPR-Cas9 metabolic screens reveal critical redox control points dependent on the KEAP1-NRF2 regulatory axis ENSG00000125166 ENSG00000130957 ENSG00000262785 ENSG00000197713 ENSG00000160883 ENSG00000108515 ENSG00000067057 ENSG00000153574 ENSG00000131828 ENSG00000065833 ENSG00000163114 ENSG00000074800 ENSG00000049239 ENSG00000173599 ENSG00000172005 ENSG00000110435 ENSG00000164708 ENSG00000136872 ENSG00000146701 ENSG00000082212 ENSG00000091140 ENSG00000159399 ENSG00000152556 PMC8804062__F1 Neurobiological Opportunities in Diabetic Polyneuropathy ENSG00000002330 ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000139687 ENSG00000075213 PMC5852779__F2 TLR2, TLR4, and TLR5 signaling pathways ENSG00000183735 ENSG00000187554 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC6326689__F3 Molecular pathways modulating lifespan via control of the translation machinery ENSG00000155506 ENSG00000128272 ENSG00000284161 ENSG00000167658 PMC8874935__F3 Vav Proteins in Development of the Brain: A Potential Relationship to the Pathogenesis of Congenital Zika Syndrome? ENSG00000291603 ENSG00000070831 ENSG00000163914 PMC3334407__F5 Schematic model for inhibition of cell proliferation by EGCG analogs ENSG00000198793 PMC6594015__F6 Schematic depiction ENSG00000005882 ENSG00000198793 PMC4915230__F1 Cell signaling pathway through which DD complex elicits a balance between survival and programmed cell death ENSG00000137275 ENSG00000102871 ENSG00000157625 ENSG00000083799 ENSG00000168040 ENSG00000127191 ENSG00000285379 PMC12223915__F6 Serum Pharmacology Combined with Network Pharmacology Reveals the Effects and Mechanisms of Ganmai Dazao Decoction in the Treatment of Depression ENSG00000169291 ENSG00000108557 ENSG00000146469 PMC4051765__F1 Responses of the Insulin Signaling Pathways in the Brown Adipose Tissue of Rats following Cold Exposure ENSG00000002330 ENSG00000110395 ENSG00000106070 ENSG00000198793 ENSG00000220205 PMC9559204__F8 Mycobacterial acyl carrier protein suppresses TFEB activation and upregulates miR-155 to inhibit host defense ENSG00000198793 ENSG00000112561 PMC7700034__F7 Schematic outline representing the acute effect of AB (1-42) on cholesterol dyshomeostasis-induced neurotoxicity and its possible protection through quinovic acid ENSG00000125538 ENSG00000113161 ENSG00000131095 ENSG00000102003 ENSG00000164305 ENSG00000079999 PMC7830632__F1 Apoptosis, inflammation and endoplasmic reticulum (ER) stress regulated by the caspase family ENSG00000163568 ENSG00000119777 ENSG00000026103 PMC3658451__F2 Caspase recruitment domain-containing sensors and adaptors in intestinal innate immunity ENSG00000174125 ENSG00000239732 ENSG00000167207 ENSG00000187796 ENSG00000187554 ENSG00000136869 ENSG00000164342 PMC7830632__F2 Response model of Ras/phosphatidylinositol 3-kinase (PI3K)/Akt/mTOR pathway to the growth factors, amino acids and glucose levels ENSG00000130147 ENSG00000169047 ENSG00000198793 ENSG00000164327 ENSG00000127884 PMC7723170__F1 Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5021946__F4 Subpathway-CorSP: Identification of metabolic subpathways via integrating expression correlations and topological features between metabolites and genes of interest within pathways ENSG00000065357 ENSG00000113492 ENSG00000167720 ENSG00000172482 ENSG00000116761 ENSG00000178445 PMC6429193__F1 JAK2-STAT5-SOCS pathway and domain structure of STAT5 ENSG00000147162 ENSG00000198408 ENSG00000291971 ENSG00000149269 ENSG00000198793 ENSG00000163914 ENSG00000121058 ENSG00000132964 PMC4808242__F1 Obesity-linked metabolic pathways susceptible to diet induced epigenetic perturbation ENSG00000245848 ENSG00000129757 ENSG00000143379 ENSG00000115138 ENSG00000169710 ENSG00000113532 ENSG00000134046 ENSG00000276996 ENSG00000132170 PMC7764689__F3 Ingenuity pathway analysis (IPA) network analysis of the modified proteins in response to BK 48 h stimulation relative to control in RASMC ENSG00000041982 ENSG00000089159 PMC3745259__F1 The hexosamine biosynthetic pathway provides the donor substrate for O-GlcNAcylation and other types of protein glycosylation ENSG00000147162 ENSG00000013375 PMC316921__F6 Wnt signaling in the early C. elegans embryo ENSG00000134982 PMC3745259__F2 O-GlcNAc is involved in the cellular stress response ENSG00000284774 ENSG00000147162 ENSG00000185591 PMC4369723__F5 Integrating Clinical Indexes into Four-Diagnostic Information Contributes to the Traditional Chinese Medicine (TCM) Syndrome Diagnosis of Chronic Hepatitis B ENSG00000115415 ENSG00000163235 ENSG00000138798 ENSG00000185591 ENSG00000168610 ENSG00000146648 PMC8304542__F2 Anti-VEGF(R) Drug Discovery Legacy: Improving Attrition Rates by Breaking the Vicious Cycle of Angiogenesis in Cancer ENSG00000165197 ENSG00000112715 ENSG00000150630 PMC11394487__F5 AMPK signaling pathway ENSG00000177169 ENSG00000167323 ENSG00000198793 ENSG00000284161 ENSG00000113161 ENSG00000167658 ENSG00000169710 ENSG00000141564 ENSG00000167965 ENSG00000187840 ENSG00000157184 ENSG00000266173 ENSG00000001626 PMC8873123__F3 Autophagy plays a double-edged sword role in liver diseases ENSG00000198793 ENSG00000189403 ENSG00000145782 ENSG00000057663 ENSG00000198925 PMC8288800__F5 Long noncoding RNAs in metastasis site-specific tropism ENSG00000108691 ENSG00000241058 ENSG00000168610 PMC11394487__F6 ERK/MAPK signaling pathway ENSG00000172680 ENSG00000002330 ENSG00000157764 ENSG00000291971 ENSG00000141068 ENSG00000281877 ENSG00000099942 ENSG00000187840 ENSG00000089159 ENSG00000132170 ENSG00000160691 ENSG00000107263 ENSG00000120899 ENSG00000115415 ENSG00000109270 ENSG00000131196 ENSG00000158050 PMC6070639__F2 PA induces the upregulation of PGC-1A expression via multiple signaling pathways ENSG00000198793 ENSG00000096088 ENSG00000106459 PMC8288800__F3 Long noncoding RNAs regulate metastasis via various pathways using diverse mechanisms ENSG00000169554 ENSG00000198793 ENSG00000136997 ENSG00000168036 ENSG00000008083 PMC4149521__F4 Gene Expression Profiling Reveals Epithelial Mesenchymal Transition (EMT) Genes Can Selectively Differentiate Eribulin Sensitive Breast Cancer Cells ENSG00000019991 ENSG00000148400 ENSG00000138798 ENSG00000185591 ENSG00000151617 ENSG00000146648 PMC7578566__F3 Cellular senescence by extracellular matrix during chronic fibrotic diseases ENSG00000134982 ENSG00000168036 PMC11394487__F7 PI3K/AKT signaling pathway ENSG00000140992 ENSG00000033327 ENSG00000002330 ENSG00000175793 ENSG00000105401 ENSG00000169756 ENSG00000198793 ENSG00000168036 ENSG00000197442 ENSG00000171791 ENSG00000124762 ENSG00000187840 ENSG00000160691 PMC4763954__F1 Fas:FasL interactions ENSG00000056558 ENSG00000168040 ENSG00000026103 PMC7432812__F2 Schema for the mechanisms for different types of cell deaths ENSG00000278718 ENSG00000002330 ENSG00000102871 ENSG00000167468 ENSG00000111684 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000135116 ENSG00000285379 ENSG00000104081 ENSG00000026103 PMC11394487__F2 Mitochondrial biogenesis pathways ENSG00000111837 ENSG00000148840 PMC5295669__F2 Modes of DNA synthesis ENSG00000140451 ENSG00000132646 ENSG00000051180 ENSG00000177084 ENSG00000122008 PMC8288800__F6 Long noncoding RNAs and tumour microenvironment ENSG00000108691 PMC8490516__F8 Kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis ENSG00000072274 ENSG00000049768 PMC11953055__F8 Schematic illustration summarizing the mechanism by which NSUN2 promotes colorectal cancer (CRC) ENSG00000158290 ENSG00000037474 ENSG00000168610 ENSG00000146648 PMC4452855__F2 Types I and III IFNs canonical signaling pathways ENSG00000184979 ENSG00000236637 ENSG00000188379 ENSG00000187608 ENSG00000105397 ENSG00000185436 ENSG00000276561 ENSG00000142166 PMC9305279__F1 Friend or Foe? Implication of the autophagy-lysosome pathway in SARS-CoV-2 infection and COVID-19 ENSG00000177169 ENSG00000130234 ENSG00000112561 ENSG00000145782 PMC9305279__F2 Friend or Foe? Implication of the autophagy-lysosome pathway in SARS-CoV-2 infection and COVID-19 ENSG00000280616 ENSG00000177169 ENSG00000166887 ENSG00000130234 ENSG00000099940 ENSG00000145782 ENSG00000166471 ENSG00000118640 ENSG00000136874 ENSG00000062716 PMC6895510__F1 Regenerative abilities contribute to the application of BM-MSC in psychocardiological disease ENSG00000180210 ENSG00000176692 ENSG00000110799 ENSG00000148400 ENSG00000131095 PMC9015857__F10 Recent Progress in Traditional Chinese Medicines and Their Mechanism in the Treatment of Allergic Rhinitis ENSG00000213658 ENSG00000124181 PMC6996643__F2 Meta‐analysis and field synopsis of genetic variants associated with the risk and severity of acute pancreatitis ENSG00000284881 ENSG00000100906 ENSG00000170458 ENSG00000118503 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC8534037__F2 Microenvironmental Reactive Oxygen Species in Colorectal Cancer: Involved Processes and Therapeutic Opportunities ENSG00000019991 ENSG00000168036 PMC5752239__F9 The putative mechanism involved in the transdifferentiation from SESCs to CECs ENSG00000168036 ENSG00000088387 PMC11475022__F6 GSEA of 18 patients with CTEPH from the GEO database ENSG00000116898 ENSG00000051523 ENSG00000112972 ENSG00000108055 ENSG00000073578 ENSG00000134982 ENSG00000095321 ENSG00000103222 ENSG00000164190 ENSG00000150787 ENSG00000169919 ENSG00000102172 ENSG00000141298 ENSG00000117724 ENSG00000038382 ENSG00000157184 ENSG00000117054 ENSG00000119397 ENSG00000134824 ENSG00000172005 ENSG00000126001 ENSG00000006327 ENSG00000196914 ENSG00000112996 PMC7736044__F1 Interplay between cysteine protease activation and mitochondrial deteriorating processes in MS myelin degeneration ENSG00000005893 PMC3887753__F1 Sequential pathway leading to renal ischemia-reperfusion injury PMC2695499__F10 Changes in OSM signaling ENSG00000145623 ENSG00000099985 ENSG00000105397 ENSG00000168610 PMC12199726__F1 Molecular and cellular signaling of intestinal tuft cells in response to infections ENSG00000197943 ENSG00000269404 ENSG00000070985 ENSG00000166090 PMC3532050__F1 NFKB inhibition by A20 in the TNFR1 signaling pathway ENSG00000123091 ENSG00000078747 ENSG00000102871 ENSG00000082512 ENSG00000173039 ENSG00000127191 PMC3376977__F2 NK cells sense tumors, course of disease and treatments ENSG00000134086 ENSG00000111537 ENSG00000115415 ENSG00000186716 ENSG00000276051 PMC8309156__F1 Behind the Adaptive and Resistance Mechanisms of Cancer Stem Cells to TRAIL ENSG00000138075 ENSG00000168040 PMC8419687__F2 IL‐4‐induced changes in metabolism and their effects on gene expression ENSG00000135218 ENSG00000288145 ENSG00000137265 ENSG00000118520 PMC9082817__F7 Transcriptomic Profiles of Splenic CD19+ B Cells in Mice Chronically Infected With the Larval Echinococcus granulosus ENSG00000165030 ENSG00000170558 ENSG00000175352 ENSG00000196743 ENSG00000010278 ENSG00000163737 ENSG00000145623 ENSG00000117400 ENSG00000157227 ENSG00000127954 ENSG00000117335 ENSG00000196352 ENSG00000026652 ENSG00000108821 ENSG00000115594 ENSG00000275584 ENSG00000005961 ENSG00000000971 ENSG00000185885 ENSG00000140545 ENSG00000211445 ENSG00000108839 ENSG00000136960 ENSG00000196502 ENSG00000133110 ENSG00000115415 ENSG00000170458 ENSG00000185201 ENSG00000134853 ENSG00000135404 ENSG00000174059 ENSG00000198734 PMC514582__F10 Schematic of Nef signaling pathways and their relationship with Nef’s biologic effects in podocytes ENSG00000291971 ENSG00000168610 PMC11484033__F6 Lats-IN-1 protects cardiac function and promotes regeneration after myocardial infarction by targeting the hippo pathway ENSG00000150457 ENSG00000131023 PMC12153738__F4 PGRN’s multifaceted roles in lysosomal function, autophagy, and metabolism impacting cardiovascular health ENSG00000135218 ENSG00000112561 PMC3847559__F5 Combining DC vaccination with immune checkpoint blockade PMC12153738__F3 Progranulin (PGRN) in vascular pathophysiology ENSG00000170365 ENSG00000142627 ENSG00000136869 ENSG00000134243 ENSG00000162692 PMC5784573__F2 Radiation effects on antitumor immune responses: current perspectives and challenges ENSG00000149311 ENSG00000108691 ENSG00000164430 ENSG00000161921 ENSG00000197405 ENSG00000189403 ENSG00000136869 ENSG00000162692 ENSG00000026103 PMC5968744__F1 Schematic representation of the signal transduction pathway of ATF3 protecting against I/R-induced inflammation, apoptosis, or myocardial injury in various organs ENSG00000162772 PMC4982433__F3 Signalling pathway and targeted therapy in gastric cancer ENSG00000118058 ENSG00000019991 ENSG00000066468 ENSG00000198793 ENSG00000055609 ENSG00000128602 PMC7485092__F2 Innate and adaptive immune responses in SARS-CoV-2 Infection ENSG00000108691 ENSG00000111537 ENSG00000163734 ENSG00000113520 PMC8670437__F7 In situ Metabolomics of Metabolic Reprogramming Involved in a Mouse Model of Type 2 Diabetic Kidney Disease ENSG00000140287 ENSG00000026103 PMC2874622__F2 The Role Of Mitochondria In The Mammalian Antiviral Defense System ENSG00000088888 ENSG00000140740 ENSG00000116688 ENSG00000160703 PMC9140097__F1 Chromosomal Instability in Chronic Myeloid Leukemia: Mechanistic Insights and Effects ENSG00000186716 ENSG00000145321 ENSG00000138385 PMC8002454__F1 Rheb-mTORC1 signaling pathway in neurodegeneration ENSG00000177169 ENSG00000198793 ENSG00000145979 ENSG00000167965 PMC2722250__F2 Silent chromatin assembly in budding and fission yeast ENSG00000166869 ENSG00000187446 ENSG00000198576 PMC8637215__F7 Cytokine and Complement Response in the Glaucomatous BB1-CTGF Mouse Model ENSG00000169245 ENSG00000274619 ENSG00000081041 ENSG00000163739 PMC12024285__F12 1-DNJ alleviating OS in porcine GCs ENSG00000128272 ENSG00000116688 ENSG00000156026 ENSG00000096088 PMC2707511__F6 DNA Topoisomerase I Inhibitors: Chemistry, Biology and Interfacial Inhibition ENSG00000012061 ENSG00000012048 ENSG00000154920 ENSG00000042088 PMC9524011__F2 Dysfunction and ceRNA network of the tumor suppressor miR-637 in cancer development and prognosis ENSG00000136929 ENSG00000138798 ENSG00000168036 ENSG00000176046 ENSG00000128342 ENSG00000168610 ENSG00000146648 ENSG00000125084 PMC3183400__F4 New Insights into insulin resistance in the diabetic heart ENSG00000169047 ENSG00000168610 PMC8231807__F1 FGFR Inhibitors in Oncology: Insight on the Management of Toxicities in Clinical Practice ENSG00000157764 ENSG00000019186 ENSG00000198793 PMC5226550__F7 Connexin43 recruits PTEN and Csk to inhibit c-Src activity in glioma cells and astrocytes ENSG00000291971 PMC4779427__F6 DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States ENSG00000107779 ENSG00000138347 ENSG00000189058 ENSG00000065559 ENSG00000168036 ENSG00000158517 ENSG00000116701 ENSG00000173391 ENSG00000124762 ENSG00000016082 ENSG00000069431 ENSG00000152137 ENSG00000204217 ENSG00000115461 PMC7310212__F1 Modeling the Tumor Microenvironment and Pathogenic Signaling in Bone Sarcoma ENSG00000198793 ENSG00000163914 ENSG00000131023 ENSG00000140443 PMC4955846__F1 Toll-like Receptors, Triggering Receptor Expressed on Myeloid Cells Family Members and Receptor for Advanced Glycation End-products in Allergic Airway Inflammation ENSG00000175104 ENSG00000168610 ENSG00000184216 PMC6944218__F5 PCB153 exposure altered forkhead box O (FOXO) signaling pathway ENSG00000087095 ENSG00000166349 ENSG00000171105 ENSG00000005882 ENSG00000138798 ENSG00000126457 ENSG00000127528 ENSG00000175097 ENSG00000168610 ENSG00000149311 ENSG00000123374 ENSG00000145782 ENSG00000146648 ENSG00000140443 ENSG00000168685 PMC9086899__F4 BMPs in the Regulation of Osteoclasts Resorption and Bone Remodeling: From Experimental Models to Clinical Applications ENSG00000170365 ENSG00000204217 PMC6479341__F1 The role of unfolded protein response (UPR) in cell survival upon induction of ER stress ENSG00000128272 ENSG00000144895 PMC2677752__F1 Brain arteriovenous malformation biology relevant to hemorrhage and implication for therapeutic development ENSG00000106004 PMC6050934__F7 NOX4/TRPC6 pathway is important in podocyte calcium regulation and renal damage progression in diabetic kidney disease ENSG00000086991 ENSG00000137672 ENSG00000047936 PMC11015223__F9 OMA1 competitively binds to HSPA9 to promote mitophagy and activate the cGAS–STING pathway to mediate GBM immune escape ENSG00000162600 PMC4223653__F2 Neurology of mTOR ENSG00000177169 ENSG00000138798 ENSG00000145979 ENSG00000196712 PMC4223653__F3 Neurology of mTOR ENSG00000177169 ENSG00000083290 ENSG00000198793 ENSG00000196712 PMC8137566__F7 Activation of Wnt/Beta-catenin signaling pathway induced by cooperative activity of ALK and N-Myc ENSG00000105894 ENSG00000138795 ENSG00000168036 ENSG00000215301 PMC11489333__F8 Positive feedback for self-driving of NK-92AFR-CAR-CXCR3A cells based on IFNG and TNFA synergistically induced high CXCL10 expression ENSG00000169245 ENSG00000115415 ENSG00000027697 PMC6787556__F4 NAD+ Depletion and Impaired Mitophagy Are Pivotal Events in Common Neurodegenerative Diseases ENSG00000143799 ENSG00000105835 ENSG00000157064 PMC8282409__F2 New Insights on the Early Interaction Between Typhoid and Non-typhoid Salmonella Serovars and the Host Cells ENSG00000174123 ENSG00000162711 ENSG00000117228 ENSG00000136869 ENSG00000091106 ENSG00000276068 PMC5372489__F2A Systematic Study of Dysregulated MicroRNA in Type 2 Diabetes Mellitus ENSG00000120833 ENSG00000171105 ENSG00000169047 ENSG00000180008 PMC6787556__F1 Nicotinamide Adenine Dinucleotide (NAD+) Production and Catabolism in Mammalian Cells ENSG00000105835 ENSG00000180773 ENSG00000221955 ENSG00000278488 ENSG00000146477 ENSG00000157064 ENSG00000173614 ENSG00000008130 PMC9284792__F11 Circular RNA circPOLR2A promotes clear cell renal cell carcinoma progression by facilitating the UBE3C-induced ubiquitination of PEBP1 and, thereby, activating the ERK signaling pathway ENSG00000284832 ENSG00000009335 ENSG00000198492 ENSG00000102977 PMC8160143__F8 Bacterial and viral induced expression of IL22 ENSG00000171855 ENSG00000288411 ENSG00000115008 ENSG00000104432 PMC9164251__F1 Exploiting Extracellular Vesicles Strategies to Modulate Cell Death and Inflammation in COVID-19 ENSG00000213928 ENSG00000130234 ENSG00000276561 ENSG00000142166 PMC536026__F1 Schematic of the Gp1 mGluR/FMRP pathway PMC4671457__F5 A, B) Functional analyses of target genes of the differentially expressed miRNAs in MAPK signal pathway ENSG00000087095 ENSG00000172680 ENSG00000170458 ENSG00000197471 ENSG00000148798 ENSG00000138798 ENSG00000177606 ENSG00000130159 ENSG00000175104 ENSG00000127191 ENSG00000062524 ENSG00000026103 PMC6441662__F5 Fibroblast growth factor receptor 4 signalling pathway in cancer ENSG00000160867 PMC7141219__F3 Upstream network analysis of the proteins from endothelial cells exposed to ponatinib and Notch-1 signaling inhibition ENSG00000100906 ENSG00000177606 ENSG00000173039 PMC3663815__F7 Pathway summary of peptide array and antibody array results ENSG00000002330 ENSG00000157764 ENSG00000150907 ENSG00000169047 ENSG00000198793 PMC7641573__F5 Inhibition of PI3K/Akt signaling suppresses epithelial-to-mesenchymal transition in hepatocellular carcinoma through the Snail/GSK-3/beta-catenin pathway ENSG00000170558 ENSG00000168036 PMC9321501__F3 Investigating the molecular mechanisms of Tamoxifen on the EMT pathway among patients with breast cancer ENSG00000100519 ENSG00000065328 ENSG00000117650 ENSG00000166851 ENSG00000138160 ENSG00000140464 ENSG00000117399 ENSG00000089159 ENSG00000183765 PMC6600399__F2 Regulation and role of the PI3K-AKT-mTORC1 pathway in ribosome biogenesis and translation initiation ENSG00000155506 ENSG00000163435 ENSG00000166173 ENSG00000100227 ENSG00000136997 ENSG00000284161 ENSG00000155792 ENSG00000179632 PMC8667978__F1 Managing Antiphospholipid Syndrome in Children and Adolescents: Current and Future Prospects ENSG00000239732 ENSG00000136869 ENSG00000062485 PMC9321501__F5 Investigating the molecular mechanisms of Tamoxifen on the EMT pathway among patients with breast cancer ENSG00000145632 ENSG00000151725 ENSG00000120833 ENSG00000114346 ENSG00000178999 ENSG00000131153 ENSG00000087586 ENSG00000166851 ENSG00000088970 ENSG00000137807 ENSG00000198901 ENSG00000094804 ENSG00000120899 ENSG00000089685 ENSG00000173757 ENSG00000112984 ENSG00000136504 ENSG00000134690 ENSG00000149503 PMC5577045__F8 Signaling pathways altered by XWL-1-48 ENSG00000188486 ENSG00000149311 ENSG00000026103 PMC8722763__F6 Ailanthone suppresses the activity of human colorectal cancer cells through the STAT3 signaling pathway ENSG00000170558 ENSG00000168610 PMC3937030__F1 MTOR pathway signaling pathway ENSG00000102034 ENSG00000198793 ENSG00000173599 ENSG00000167658 PMC2728865__F2 Transcriptional Regulation of Metabolism Associated With the Increased Desiccation Resistance of the Cactophilic Drosophila mojavensis PMC6045671__F1 Hippo pathway ENSG00000186575 ENSG00000101109 ENSG00000144560 ENSG00000139926 ENSG00000018408 ENSG00000150457 ENSG00000131023 PMC10670380__F3 Multi-level functional integration of extended regions of the human genome, above and beyond individual noncoding RNAs PMC5441763__F5 CD19 is the linchpin between CXCR4, the BCR, and the actin cytoskeleton ENSG00000177455 ENSG00000107562 ENSG00000150907 ENSG00000121966 PMC12110894__F7 Expression changes of key enzyme genes for flavonoid synthesis pathway in different light treatments ENSG00000160752 ENSG00000110934 ENSG00000167508 PMC3988961__F3 Pathway analysis ENSG00000117228 ENSG00000073060 ENSG00000178573 ENSG00000153823 ENSG00000130522 ENSG00000177606 ENSG00000138311 ENSG00000198670 ENSG00000162772 PMC4732882__F1 Metabolism and the circadian clock converge ENSG00000105835 ENSG00000096717 PMC8997905__F2 Specific NLRP3 Inflammasome Assembling and Regulation in Neutrophils: Relevance in Inflammatory and Infectious Diseases ENSG00000162711 ENSG00000167207 ENSG00000125538 ENSG00000136869 ENSG00000171051 PMC11498046__F4 Preparation of PGRsEV-siYTHDF1 ENSG00000111537 ENSG00000198053 ENSG00000149658 ENSG00000168036 ENSG00000155760 PMC10564423__F8 Schematic diagram illustrated how core fucosylation regulated alveolar epithelial cells senescence in pulmonary fibrosis through TGFB/Smad2/3 pathway in vivo and in vitro ENSG00000197299 PMC5360546__F4 Hippo pathway ENSG00000131023 PMC9480797__F3 Molecular pathways in glioblastoma-derived stem cells to identify effective drug agents: A bioinformatics study ENSG00000115163 ENSG00000114346 ENSG00000130826 ENSG00000131747 ENSG00000101057 ENSG00000291964 ENSG00000087586 ENSG00000145386 ENSG00000137807 ENSG00000138778 ENSG00000117650 ENSG00000134057 ENSG00000280610 ENSG00000112984 ENSG00000164362 ENSG00000121621 PMC7409586__F1 Human Disorders Affecting the Selenocysteine Incorporation Pathway Cause Systemic Selenoprotein Deficiency ENSG00000180098 ENSG00000284869 ENSG00000156482 ENSG00000179918 ENSG00000179988 PMC4547750__F4 Phosphotyrosine Substrate Sequence Motifs for Dual Specificity Phosphatases ENSG00000108861 ENSG00000198793 ENSG00000101224 ENSG00000164086 PMC2735600__F7 Contribution of Rho to canonical Wnt3A signaling ENSG00000154342 ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC10996135__F6 Distribution of common targets in the two most associated pathways ENSG00000177455 ENSG00000087095 ENSG00000103479 ENSG00000002330 ENSG00000170458 ENSG00000102871 ENSG00000186716 ENSG00000104894 ENSG00000130159 ENSG00000026103 PMC6356823__F2 Predictive pathway for polyamine synthesis in microalgal cells ENSG00000112977 ENSG00000102172 PMC7409586__F3 Human Disorders Affecting the Selenocysteine Incorporation Pathway Cause Systemic Selenoprotein Deficiency ENSG00000145321 ENSG00000007908 PMC11868327__F3 Molecular cascade of the involvement of GluD2 or GluRD2 in cerebellar cell death ENSG00000173599 ENSG00000057663 PMC6828590__F13 Regulatory mechanism of the VEGF signal pathway in different groups ENSG00000132906 ENSG00000002330 ENSG00000070831 ENSG00000291971 ENSG00000087842 PMC4420611__F5 Lysosome pathway ENSG00000107331 ENSG00000183878 ENSG00000018510 ENSG00000002549 PMC6828590__F11 Regulatory mechanism of the PI3K-AKT signal pathway in different groups ENSG00000132906 ENSG00000159224 ENSG00000002330 ENSG00000105401 ENSG00000198793 ENSG00000169047 ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000069482 ENSG00000186716 ENSG00000136997 ENSG00000136869 PMC6828590__F12 Regulatory mechanism of the MAPK signal pathway in different groups ENSG00000087095 ENSG00000172680 ENSG00000075142 ENSG00000130522 ENSG00000138798 ENSG00000130159 ENSG00000127191 ENSG00000081189 ENSG00000170458 ENSG00000149269 ENSG00000173599 ENSG00000175104 ENSG00000146648 ENSG00000196712 ENSG00000026103 PMC7952883__F3 General mechanisms of sildenafil in different types of cancer ENSG00000198793 ENSG00000103222 ENSG00000168036 ENSG00000118520 ENSG00000118777 PMC4336821__F7 Bile Acids Regulate Nuclear Receptor (Nur77) Expression and Intracellular Location to Control Proliferation and Apoptosis ENSG00000101773 ENSG00000135446 ENSG00000118971 PMC6745167__F2 Results of network analysis: differentially regulated proteins from the SILAC approach are indicated in green (TCam-2) or in red (NTERA-2) ENSG00000169291 ENSG00000065361 ENSG00000100994 ENSG00000243709 ENSG00000162551 ENSG00000138798 ENSG00000137563 ENSG00000187244 ENSG00000146648 PMC5354081__F1 Examples of Metabolic Pathway Linking Gut Microbiota to Cardiovascular Diseases ENSG00000162711 ENSG00000135218 ENSG00000167910 ENSG00000135929 PMC11727624__F1 Biological processes of the canonical Hedgehog (Hh) signaling pathway ENSG00000151657 ENSG00000164161 ENSG00000128602 PMC4854486__F1 Pancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational Analysis ENSG00000159224 ENSG00000102452 ENSG00000010310 PMC5460031__F10 IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression ENSG00000283780 ENSG00000148400 ENSG00000127954 ENSG00000163220 ENSG00000163739 ENSG00000082512 ENSG00000108688 ENSG00000163661 ENSG00000175104 ENSG00000127191 ENSG00000163702 PMC3155635__F3 Functional pathway analysis of the 12-gene genomic instability signature using Ingenuity Pathway Analysis ENSG00000132906 ENSG00000112576 ENSG00000275385 ENSG00000108349 ENSG00000087586 ENSG00000129514 ENSG00000171791 ENSG00000145113 ENSG00000134057 ENSG00000135446 ENSG00000102245 ENSG00000136997 ENSG00000164362 PMC7754529__F3 Co-expression pattern of the most significantly enriched pathways of differentially expressed genes involved in post-traumatic stress disorder ENSG00000171105 ENSG00000280962 ENSG00000160551 ENSG00000109320 ENSG00000138798 ENSG00000291431 ENSG00000269335 ENSG00000115904 ENSG00000213341 ENSG00000099942 ENSG00000121879 ENSG00000008735 ENSG00000179295 ENSG00000183735 ENSG00000163235 ENSG00000144566 ENSG00000127588 ENSG00000146648 ENSG00000114279 ENSG00000164086 PMC8160963__F1 Identifying Novel Actionable Targets in Colon Cancer ENSG00000197081 ENSG00000157764 ENSG00000134982 PMC3082499__F5 Anti-apoptotic mechanisms of Akt ENSG00000002330 ENSG00000198793 PMC8160963__F2 Identifying Novel Actionable Targets in Colon Cancer ENSG00000166167 ENSG00000006712 ENSG00000134982 ENSG00000168036 ENSG00000173273 ENSG00000196367 PMC8160963__F3 Identifying Novel Actionable Targets in Colon Cancer PMC4126409__F1 Pathways for HJ Resolution(A) Resolvases RuvC and GEN1 digest HJs to generate linear products with single nicks (carets) ENSG00000178295 ENSG00000154920 ENSG00000188827 PMC3082499__F2 Mediators of the extrinsic pathway of PCD by Fas and TNFR-1 signaling ENSG00000102871 ENSG00000168040 ENSG00000026103 PMC321458__F8 Model of the role of RNase MRP in cell cycle control ENSG00000136425 ENSG00000134982 ENSG00000114127 PMC8301371__F8 TLR7 Activation of Macrophages by Imiquimod Inhibits HIV Infection through Modulation of Viral Entry Cellular Factors ENSG00000105397 ENSG00000172936 ENSG00000127191 ENSG00000168610 PMC7461042__F2 HIF1 signalling pathway ENSG00000134086 ENSG00000138798 ENSG00000072274 PMC6454084__F1 Putative palmitoylated proteins of the mechanistic target of rapamycin (mTOR) signaling pathway ENSG00000100150 ENSG00000114388 ENSG00000198793 ENSG00000145979 ENSG00000085415 ENSG00000127580 ENSG00000141564 ENSG00000167965 ENSG00000164654 ENSG00000103091 PMC3116244__F1 Signaling Pathways Altered in Hepatic Cancer Stem Cells ENSG00000165556 ENSG00000138795 ENSG00000002330 ENSG00000197081 ENSG00000119888 ENSG00000134982 ENSG00000198793 ENSG00000164362 ENSG00000168036 ENSG00000168610 PMC6535055__F9 The mechanism graph of the regulatory network of PIEZO2 under different circumstance including normal (A) and cancer (B) ENSG00000154864 ENSG00000064309 PMC6839745__F1 Structure and treatment strategy of TAT-CLs-DHA/siRNA ENSG00000125538 ENSG00000189403 ENSG00000172936 ENSG00000136869 PMC7835870__F1 Metabolic conversion pathway from the essential omega-3 PUFA, ALA, to longer-chain omega-3 PUFAs, EPA, DPA and DHA ENSG00000134824 ENSG00000149485 ENSG00000197977 PMC8280825__F1 Mitochondrial apoptosis pathway and opportunities for pharmacological inhibition ENSG00000162711 ENSG00000138035 ENSG00000164430 PMC8137978__F1 Ferroptosis in Acute Respiratory Distress Syndrome ENSG00000168003 ENSG00000135423 ENSG00000151012 ENSG00000167468 PMC8553038__F2 Exosomes: Emerging Cell-Free Based Therapeutics in Dermatologic Diseases ENSG00000162552 ENSG00000087245 ENSG00000000003 ENSG00000074319 ENSG00000110651 ENSG00000168036 ENSG00000010278 ENSG00000168610 ENSG00000121966 ENSG00000135404 ENSG00000127324 ENSG00000100985 ENSG00000096717 PMC6177564__F2 Schematic illustrations of identified pathways in hepatitis C virus-induced liver carcinogenesis ENSG00000168036 PMC3093193__F2 Update on the regulation of mammalian melanocyte function and skin pigmentation ENSG00000019991 ENSG00000157404 ENSG00000125398 ENSG00000115138 ENSG00000136160 ENSG00000080166 ENSG00000107165 ENSG00000124205 ENSG00000064300 PMC8315846__F6 MAPK and Notch-Mediated Effects of Meso-Xanthin F199 Compounds on Proliferative Activity and Apoptosis of Human Melanocytes in Three-Dimensional Culture ENSG00000172936 ENSG00000175104 ENSG00000124212 ENSG00000184216 PMC5561186__F8 Schematic overview of effects of metformin on gene expression and metabolism in human adrenal H295R cells, focused on mitochondria and steroidogenesis ENSG00000108515 ENSG00000104381 ENSG00000175567 ENSG00000160471 PMC5576886__F1 Impact of Base Excision DNA Repair in Age-Related Neurodegenerative Diseases ENSG00000109674 ENSG00000292286 ENSG00000105486 ENSG00000132781 ENSG00000132646 ENSG00000139372 ENSG00000129071 ENSG00000140398 ENSG00000177084 PMC3025761__F1 Schematic illustration of the various steps involved in the ubiquitin proteasome pathway and general architecture of the cullin 1 (CRL1) and cullin 4 (CRL4)-based E3 ubiquitin ligases ENSG00000100387 ENSG00000132646 ENSG00000113558 ENSG00000167986 PMC2769052__F9 Schematic representation of a potential mechanism of IFN-Gamma- and STAT3-dependent cell growth modulated by TSC2/mTOR signaling pathway ENSG00000111537 ENSG00000198793 ENSG00000168610 PMC7352671__F2 Sorafenib resistance ENSG00000146648 PMC7123108__F2 Cordyceps militaris adenine metabolic pathway ENSG00000156110 ENSG00000196839 ENSG00000291814 PMC6785598__F4 Epigenetic regulation of stem cells ENSG00000198901 ENSG00000101751 ENSG00000139372 ENSG00000082212 ENSG00000136826 PMC8184806__F6 SARS-CoV-2 mutations in Brazil: from genomics to putative clinical conditions ENSG00000123268 PMC4880867__F1 Fzd7 receptor complexes and signalling output ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000277641 PMC11360101__F7 Cytoscape shows the interactions between 9 major components of CSAEs and 4 known kidney injury pathways ENSG00000291355 ENSG00000070831 ENSG00000137275 ENSG00000167323 ENSG00000102871 ENSG00000198793 ENSG00000067900 ENSG00000198626 ENSG00000168040 ENSG00000127191 ENSG00000109689 ENSG00000293604 ENSG00000136869 ENSG00000138741 ENSG00000285379 ENSG00000164342 PMC5549368__F1 Checkpoint inhibitors in melanoma and early phase development in solid tumors ENSG00000157764 ENSG00000163599 PMC3227454__F2 Epidermal growth factor and aging: A signaling molecule reveals a new eye opening function ENSG00000129347 ENSG00000171105 ENSG00000138798 ENSG00000146648 PMC6485421__F1 NFKB and tumor-associated macrophages ENSG00000169245 ENSG00000172936 ENSG00000118520 ENSG00000276561 ENSG00000007171 PMC4328972__F1 Metabolic disturbance in the diabetic heart and prospective therapeutic targets ENSG00000162711 ENSG00000136869 ENSG00000026103 PMC3391966__F1 Model of hedgehog action in the fetal male reproductive system ENSG00000168066 ENSG00000164690 ENSG00000139549 PMC2778015__F3 Master regulator miRNA of oncogenic and tumor suppressor ENSG00000149311 ENSG00000275700 ENSG00000164938 ENSG00000171791 PMC6065152__F2 Pancreatic cancer microenvironment participates in metastasis ENSG00000168329 ENSG00000163739 ENSG00000169429 ENSG00000136869 ENSG00000164690 ENSG00000168610 PMC5677514__F1 Oxidative cyclization of prodigiosin by an alkylglycerol monooxygenase-like enzyme ENSG00000135845 ENSG00000197563 PMC3592971__F3 Four simplified signaling pathways ENSG00000004975 ENSG00000137834 ENSG00000104365 ENSG00000196296 ENSG00000281324 ENSG00000105329 ENSG00000134982 ENSG00000050748 ENSG00000198793 ENSG00000169047 ENSG00000168036 ENSG00000127191 ENSG00000168610 ENSG00000087460 ENSG00000157240 ENSG00000170365 ENSG00000148660 ENSG00000135409 ENSG00000136997 ENSG00000185591 ENSG00000183682 ENSG00000028137 PMC5085707__F1 Stages of cancer cell colonisation of the bone ENSG00000107562 ENSG00000170558 ENSG00000036828 ENSG00000162692 ENSG00000121966 PMC11836306__F1 TORC1 pathway in humans and yeast, derived from Refs3,19 ENSG00000100150 ENSG00000198198 ENSG00000155792 ENSG00000274070 ENSG00000174206 ENSG00000217128 ENSG00000127580 ENSG00000159899 ENSG00000167965 ENSG00000239282 ENSG00000164654 ENSG00000103091 PMC3328638__F1 Glucose, fatty acid (FA) and glutamine metabolic pathways ENSG00000078237 ENSG00000159399 PMC6335266__F1 Simplified representation of the complement system, divided into pattern recognition molecules (PRMs), pathway specific and common components as well as inhibitors ENSG00000039537 ENSG00000113600 ENSG00000196352 ENSG00000117335 ENSG00000244731 ENSG00000166278 ENSG00000236625 PMC7443478__F9 Sensitization of glutamate receptor‐mediated pain behaviour via nerve growth factor‐dependent phosphorylation of transient receptor potential V1 under inflammatory conditions ENSG00000196689 PMC7593681__F9 Potential mechanism of HBO treatment on intestinal barrier after SCI ENSG00000163914 ENSG00000067900 PMC10796096__F1 cGAS-STING signaling pathway in amyotrophic lateral sclerosis (ALS) ENSG00000122566 ENSG00000183735 ENSG00000164430 ENSG00000123240 ENSG00000284099 ENSG00000165280 ENSG00000147894 PMC7664196__F3 Autophagy, Ca2+ and cancer ENSG00000126775 ENSG00000167323 ENSG00000293604 ENSG00000198793 PMC7664196__F2 Apoptosis and Calcium (Ca2+) dynamics in cancer ENSG00000163930 ENSG00000156026 ENSG00000120868 ENSG00000168040 ENSG00000140464 ENSG00000026103 PMC4136471__F2 Cellular and molecular interactions between HCL cells and their microenvironment ENSG00000178860 ENSG00000107562 ENSG00000186716 ENSG00000026508 ENSG00000010671 ENSG00000121966 PMC8632547__F3 Hippo Signaling Pathway: The Trader of Tumor Microenvironment ENSG00000108691 ENSG00000163739 ENSG00000197905 ENSG00000007866 ENSG00000074219 PMC8632547__F4 Hippo Signaling Pathway: The Trader of Tumor Microenvironment ENSG00000291971 ENSG00000163914 ENSG00000197905 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC8632547__F1 Hippo Signaling Pathway: The Trader of Tumor Microenvironment ENSG00000186575 ENSG00000149930 ENSG00000160551 ENSG00000135090 ENSG00000144560 ENSG00000114978 ENSG00000131023 PMC8632547__F2 Hippo Signaling Pathway: The Trader of Tumor Microenvironment ENSG00000291971 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC6304368__F7 Anti-HBV mechanism of TLR3 signaling of HSCs ENSG00000213928 ENSG00000105397 ENSG00000168610 ENSG00000276561 ENSG00000164342 PMC6034666__F2 Engagement between the gut immune system and a probiotic (exemplified by Bifidobacterium longum subsp ENSG00000239732 ENSG00000115009 PMC8632547__F5 Hippo Signaling Pathway: The Trader of Tumor Microenvironment ENSG00000169071 ENSG00000134982 ENSG00000163914 ENSG00000185483 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC3481450__F6 Overlapping network between MCF-7 and ZR-75.1 cells ENSG00000120533 ENSG00000168806 ENSG00000176428 ENSG00000160783 PMC4429670__F1 Vicious cycles in bone metastasis ENSG00000167941 ENSG00000198793 PMC8095092__F2 Cardiotoxicity of the BCR-ABL1 tyrosine kinase inhibitors: emphasis on ponatinib ENSG00000033327 ENSG00000002330 ENSG00000186716 ENSG00000171791 PMC6123311__F3 Hypothalamic redox balance and leptin signaling - Emerging role of selenoproteins ENSG00000178188 ENSG00000115138 PMC7519200__F3 Innate immune system is the first line of defense against infection and injury and plays critical roles in the maintenance of brain homeostasis ENSG00000162711 ENSG00000096717 PMC5679168__F1 Contribution of BBB breakdown and dysregulated BBB transport to AD pathophysiology based on findings in animal models, as shown in and ENSG00000073921 PMC11046441__F3 Diversity of metabolic arrangements for Alpha-glucan and disaccharide pathways in the context of prokaryotes ENSG00000151657 ENSG00000111837 ENSG00000172005 ENSG00000145321 PMC3514351__F1 Ingenuity pathways analysis summary ENSG00000089692 ENSG00000125851 ENSG00000180644 ENSG00000079435 ENSG00000181195 PMC6497837__F1 Schematic showing mechanisms underlying morphine tolerance ENSG00000162711 ENSG00000177606 ENSG00000175104 ENSG00000196689 PMC4094071__F8 AEG-1 regulation of HIV-1 neuropathogenesis ENSG00000100811 ENSG00000150782 PMC7526653__F1 2HG metabolic pathway PMC6686482__F7 Schema presented the mechanism through which NOTCH1 aerobic glycolysis and signaling in PC cells were modulated by MACC1-AS1 ENSG00000148400 ENSG00000100985 PMC11576191__F1 CaMKK2 signaling pathway ENSG00000152495 ENSG00000110931 ENSG00000121853 PMC8826371__F7 Graphical representation of the possible mechanism by which the stat4 genetic polymorphism affects HCC ENSG00000138378 ENSG00000042832 ENSG00000130649 PMC9194156__F2 Neurodevelopmental disorders, immunity, and cancer are connected ENSG00000134070 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000168610 ENSG00000184216 PMC9194156__F5 Neurodevelopmental disorders, immunity, and cancer are connected ENSG00000198793 ENSG00000155792 PMC5794698__F1 Major communication pathways of the microbiota–gut–brain axis ENSG00000131096 PMC7526653__F3 Cystathionine metabolic pathway ENSG00000284320 ENSG00000092621 ENSG00000135069 ENSG00000146733 ENSG00000116761 PMC3525110__F3 Proposed model for EA signaling ENSG00000110921 PMC5778870__F1 Interaction of miRNAs as oncogenic and tumor suppressor PMC2935335__F1 The highly simplified PI3K/Akt and MAP kinase pathways in thyroid cancer ENSG00000157764 ENSG00000198793 PMC4183711__F8 Diagram depicts a model in which Eya2 and Ebf3 are positioned in the gene regulatory pathway for the development of RGCs ENSG00000108001 ENSG00000169856 ENSG00000176887 ENSG00000124766 ENSG00000064655 ENSG00000151615 ENSG00000273529 ENSG00000114315 ENSG00000016082 PMC6646339__F7 Homocysteine enhances neural stem cell autophagy in in vivo and in vitro model of ischemic stroke ENSG00000198793 PMC4755325__F1 CGAS-STING Defense Pathway and Its Counteraction by Viruses ENSG00000164430 ENSG00000088888 ENSG00000163568 ENSG00000172936 PMC4755325__F2 The cGAS-STING Defense Pathway and Its Counteraction by Viruses ENSG00000177169 ENSG00000183735 ENSG00000164430 ENSG00000119401 ENSG00000169871 ENSG00000173456 PMC9296991__F1 Galectin-3 Involvement in Cognitive Processes for New Therapeutic Considerations ENSG00000136869 ENSG00000007171 PMC4769158__F11 Proposed mechanisms by which loss of TRAF2 in keratinocytes causes a psoriasis-like skin inflammation ENSG00000162924 ENSG00000127191 PMC8431333__F5 Skin Cancers and the Contribution of Rho GTPase Signaling Networks to Their Progression ENSG00000110237 PMC9404709__F2 Understanding the Mechanism of Action of Melatonin, Which Induces ROS Production in Cancer Cells ENSG00000145020 ENSG00000096717 ENSG00000142082 PMC3903161__F1 Steps of autophagy pathway activation ENSG00000177169 ENSG00000123395 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC4325706__F3 Pathway Express analysis of the host response to IBDV infection in the spleen ENSG00000149311 ENSG00000132906 ENSG00000002330 ENSG00000102871 ENSG00000168040 ENSG00000164305 PMC4325706__F4 Pathway Express analysis of the host response to IBDV infection in the bursa ENSG00000177455 ENSG00000186716 ENSG00000152430 PMC6939687__F2 Interplay between HIF-1A and Notch during hypoxia ENSG00000105835 ENSG00000198435 PMC4327822__F5 mGluR1/5 signaling pathways relevant to protein synthesis ENSG00000005882 ENSG00000198793 ENSG00000284161 ENSG00000167658 PMC6781639__F2 VEGFR structures and their specific ligands ENSG00000112715 ENSG00000118257 ENSG00000150630 PMC8771846__F7 RhoJ facilitates angiogenesis in glioblastoma via JNK/VEGFR2 mediated activation of PAK and ERK signaling pathways ENSG00000130669 PMC6989995__F1 Toll-like receptor 4 (TLR4)-KO aggravates dextran sulfate sodium (DSS)-induced intestinal damage by attenuating cell cycle and cytokine-cytokine receptor interaction ENSG00000145604 ENSG00000132646 ENSG00000135336 ENSG00000123374 PMC6989995__F2 Toll-like receptor 4 (TLR4)-KO aggravates dextran sulfate sodium (DSS)-induced intestinal damage by attenuating TLR signaling pathways and enhancing the apoptosis pathway ENSG00000149311 ENSG00000065833 ENSG00000198517 ENSG00000291791 ENSG00000168040 ENSG00000127191 ENSG00000084774 ENSG00000115317 PMC8129546__F2 Gegen Qinlian Decoction Ameliorates Hyperuricemia-Induced Renal Tubular Injury via Blocking the Inflammatory Signaling Pathway ENSG00000145384 ENSG00000198793 ENSG00000173039 ENSG00000178726 ENSG00000118777 ENSG00000164305 ENSG00000102468 ENSG00000158125 ENSG00000132170 ENSG00000170961 ENSG00000150782 ENSG00000108691 ENSG00000005421 ENSG00000149968 ENSG00000136997 ENSG00000159346 ENSG00000096717 ENSG00000064012 ENSG00000140443 PMC10474119__F9 Mechanistic diagram summarizing the regulatory effect of TGR5 in mitochondrial dysfunction and neuroinflammation in Müller cells ENSG00000183735 ENSG00000164430 ENSG00000173599 PMC8910147__F1 CXC Chemokine Signaling in Progression of Epithelial Ovarian Cancer: Theranostic Perspectives ENSG00000163464 ENSG00000169248 ENSG00000169245 ENSG00000186810 ENSG00000107562 ENSG00000161921 ENSG00000163739 ENSG00000138755 ENSG00000168036 ENSG00000169429 ENSG00000118520 ENSG00000121966 PMC5727324__F6 DKK1–CKAP4 axis as a novel molecular target for cancer therapy and future perspectives ENSG00000155011 ENSG00000050165 ENSG00000104371 ENSG00000136026 PMC5727324__F4 DKK1 and CKAP4 signalling axis ENSG00000136026 PMC6295421__F5 Proposed mechanisms of nitrergic neurotransmission in the SIP syncytium ENSG00000146469 ENSG00000134853 PMC5727324__F2 Polarized trafficking of Wnt proteins and receptors ENSG00000154342 ENSG00000281324 ENSG00000169071 ENSG00000125084 PMC5727324__F1 ‘Two endocytic routes and two outputs model’ in the Wnt signalling pathways ENSG00000154342 ENSG00000281324 ENSG00000169071 ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC10505339__F2 NFKB signalling pathway ENSG00000104856 PMC10706418__F5 Analysis of hormone signaling transduction in response to CGMMV infection ENSG00000110934 ENSG00000221818 PMC3091762__F9 IPA representation of the complement system pathway enriched in cluster 6, 3 hours post-infestation with P ENSG00000039537 ENSG00000203710 ENSG00000244731 ENSG00000166278 ENSG00000117322 ENSG00000236625 PMC10505339__F4 BMP signalling pathway ENSG00000170365 ENSG00000137834 PMC3091762__F7 IPA representation of the canonical pathway for leukocyte extravasation signalling in cluster 4, 24 hours post-infestation with P ENSG00000163914 ENSG00000135605 PMC1570177__F1 Mathematical Modeling Identifies Inhibitors of Apoptosis as Mediators of Positive Feedback and Bistability ENSG00000132906 ENSG00000113600 ENSG00000120868 ENSG00000064012 ENSG00000164305 PMC5659885__F2 Stretch-induced actomyosin contraction in epithelial tubes: mechanotransduction pathways for tubular homeostasis ENSG00000291971 PMC8416109__F5 Advanced Computational Methodologies Used in the Discovery of New Natural Anticancer Compounds ENSG00000146648 PMC9213757__F1 Chromatin Landscape Channels DNA Double-Strand Breaks to Distinct Repair Pathways ENSG00000185513 ENSG00000012048 ENSG00000163961 ENSG00000080345 ENSG00000163104 PMC7832239__F1 Crosstalk between complement and coagulation cascade in COVID-19: There are 3 major self-regulating and overlapping pathways of complement activation system ENSG00000113600 ENSG00000182326 PMC2956119__F1 This figure shows the two distinct but ultimately converging apoptosis signaling pathways in mammals ENSG00000132906 ENSG00000120868 ENSG00000168040 ENSG00000164305 ENSG00000026103 PMC5595129__F1 An overview of roles of miRNAs as a regulator of DDR in response to radiation in cancers ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000051180 ENSG00000138385 ENSG00000139618 PMC2956119__F2 The many roles of FAS receptor signaling in the immune system ENSG00000186716 ENSG00000026103 PMC9503463__F2 NOD1, NOD2, and NLRC5 Receptors in Antiviral and Antimycobacterial Immunity ENSG00000088888 PMC6553925__F6 Summary of all identified phosphosites in LPS signaling pathway ENSG00000168884 ENSG00000183735 ENSG00000170458 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000127191 ENSG00000090376 ENSG00000184216 PMC11395329__F6 MiR-27a-5p functions in hDPCs ENSG00000163430 ENSG00000173039 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC9503463__F1 NOD1, NOD2, and NLRC5 Receptors in Antiviral and Antimycobacterial Immunity ENSG00000162711 ENSG00000167207 ENSG00000131323 PMC8129546__F8 Gegen Qinlian Decoction Ameliorates Hyperuricemia-Induced Renal Tubular Injury via Blocking the Inflammatory Signaling Pathway ENSG00000278718 ENSG00000162711 PMC2373983__F1 Human T-Cell Leukemia Virus Type 1 Blunts Signaling by Interferon Alpha ENSG00000213928 ENSG00000117228 ENSG00000187608 ENSG00000125347 ENSG00000142166 PMC2956119__F3 The many roles of FAS receptor signaling in the immune system ENSG00000132906 ENSG00000120868 ENSG00000168040 ENSG00000164305 ENSG00000026103 PMC4149467__F6 GATA regulation of Notch signaling in the intestine ENSG00000115850 ENSG00000293532 ENSG00000172238 PMC8080387__F5 Uncarboxylated osteocalcin alleviates the inhibitory effect of high glucose on osteogenic differentiation of mouse bone marrow–derived mesenchymal stem cells by regulating TP63 ENSG00000168036 PMC10505339__F1 Interaction of Wnt/Beta-catenin and Wnt/Ca2+ signalling pathways in an inflammatory environment ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC8173139__F1 Radiotherapy and Cytokine Storm: Risk and Mechanism ENSG00000162711 ENSG00000239732 ENSG00000111537 ENSG00000161921 ENSG00000121966 ENSG00000171051 PMC3064629__F6 miR-34a, MAGE-A genes, and p53 form a positive feedback loop modulating chemosensitivity in cancer cells ENSG00000292189 ENSG00000292186 ENSG00000292195 ENSG00000292187 PMC5733474__F2 Enriched PI3K/AKT signaling pathway, identified by Ingenuity Pathway Analysis based on 300 differentially expressed genes (nominal P values < 0.05) detected exclusively in both week 8 and week 12 topiramate (TPM) groups ENSG00000002330 ENSG00000198793 ENSG00000112640 ENSG00000168036 ENSG00000126458 PMC6727394__F1 Altered metabolic pathways and associated circRNAs in cancer ENSG00000169710 ENSG00000115419 PMC6727394__F2 circRNAs and the Warburg effect associated signaling pathways ENSG00000134982 ENSG00000198793 ENSG00000145321 ENSG00000168036 ENSG00000171791 ENSG00000112715 ENSG00000168610 ENSG00000140443 PMC7140961__F3 Metabolic pathway based on phenolic profiling ENSG00000102977 ENSG00000084774 PMC2575728__F2 Following the cytokine signaling pathway to leukemogenesis: a chronology ENSG00000134460 ENSG00000162924 ENSG00000187266 ENSG00000105639 PMC4066644__F2 Model of tumor heterogeneity ENSG00000164690 ENSG00000128602 PMC2583327__F10 Transcriptional and Translational Regulation of Transforming Growth FactorB Production in Response to Apoptotic Cells ENSG00000198793 PMC6199573__F1 Whole-transcriptomic Profile of SK-MEL-3 Melanoma Cells Treated with the Histone Deacetylase Inhibitor: Trichostatin A ENSG00000105329 ENSG00000134982 ENSG00000196591 ENSG00000250254 ENSG00000112118 ENSG00000205250 ENSG00000073111 ENSG00000118971 ENSG00000093009 ENSG00000175054 ENSG00000112242 ENSG00000133740 ENSG00000282899 ENSG00000027075 ENSG00000157764 ENSG00000170027 ENSG00000149311 ENSG00000145604 ENSG00000065328 ENSG00000134057 ENSG00000156970 ENSG00000135446 ENSG00000132646 ENSG00000047849 ENSG00000146648 ENSG00000147082 ENSG00000175305 PMC6721639__F1 After interacting with CD154, CD40 recruits and interacts with several adapter proteins, including TRAF1, 2, 3, 5 and 6 ENSG00000104856 ENSG00000119487 ENSG00000082512 ENSG00000173039 PMC7334537__F1 Steroidogenesis including the classic androgen pathway (dark blue) and the alternative androgen biosynthesis pathway (light blue), both resulting in the synthesis of potent 5Alpha-dihydrotestosterone (DHT) ENSG00000277893 ENSG00000127948 PMC8423434__AF1 Principles of signaling pathway modulation for enhancing human naive pluripotency induction ENSG00000168214 ENSG00000291971 ENSG00000128342 PMC5646231__F1 Regulation of Exercise-Induced Autophagy in Skeletal Muscle ENSG00000177169 ENSG00000083290 ENSG00000198793 ENSG00000158828 ENSG00000069509 PMC151063__F9 p53 induction and activation of DDR1 kinase counteract p53-mediated apoptosis and influence p53 regulation through a positive feedback loop PMC6332791__F9 A proposed model underlying the OTUB2/U2AF2 axis as an activator of the Warburg effect and tumorigenesis in NSCLC cells ENSG00000198793 ENSG00000063244 ENSG00000277276 PMC6060714__F6 Valproic acid causes radiosensitivity of breast cancer cells via disrupting the DNA repair pathway ENSG00000012048 ENSG00000051180 ENSG00000139618 PMC3529366__F6 BMP2-WNT4-FOXO1 pathway in HESC differentiation ENSG00000162552 ENSG00000170365 ENSG00000143768 ENSG00000153094 ENSG00000150907 ENSG00000168036 ENSG00000157005 PMC4999430__F1 Interplay between EPEC/EHEC and inflammasome ENSG00000162711 ENSG00000091106 ENSG00000168040 PMC8437142__F10 Morphine-induced inhibition of moderate acute intermittent hypoxia-induced phrenic long-term facilitation (pLTF) ENSG00000196531 ENSG00000136869 PMC9622720__F4 Network exploration of gene signatures underlying low birth weight induced metabolic alterations ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000002330 ENSG00000069482 ENSG00000186716 ENSG00000169047 ENSG00000136997 ENSG00000104894 PMC8585600__F1 Interleukin-6 in SARS-CoV-2 induced disease: Interactions and therapeutic applications ENSG00000239732 ENSG00000130234 ENSG00000168610 ENSG00000127948 PMC5485083__F2 Top Left: Gene expression networks activated whilst differentiating cells are treated with varying doses of escitalopram ENSG00000145362 ENSG00000165733 ENSG00000241945 ENSG00000146072 ENSG00000107447 ENSG00000151914 ENSG00000132535 ENSG00000205683 ENSG00000144713 ENSG00000136108 ENSG00000164934 PMC9308265__F8 Chronic heat stress promotes liver inflammation in broilers via enhancing NFKB and NLRP3 signaling pathway ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC8524770__F3 Sex hormones in lung cancer ENSG00000107562 ENSG00000121966 PMC8524770__F4 Sex hormones in lung cancer ENSG00000113905 ENSG00000138798 ENSG00000198793 PMC4279092__F2 Biology of IL-27 and its Role in the Host Immunity against Mycobacterium Tuberculosis ENSG00000198793 ENSG00000135404 ENSG00000105246 ENSG00000168610 PMC3874419__F4 Cross-talk of EGFR/HER2 signaling with other pathways ENSG00000168036 ENSG00000114315 ENSG00000146648 PMC10705939__F2 Schematic diagram of the regulatory pathways of K+ channels or transporters in Arabidopsis and rice ENSG00000156735 ENSG00000100429 PMC5890100__F2 Whenever there is any inflammatory stimulus to the cell, there is activation of several molecular cascades such as NFKB, Nrf2, MAPKinase, JAK/STAT, p53, PI3K/mTOR, CREB, and Wnt/Beta catenin ENSG00000104856 ENSG00000002330 ENSG00000198793 ENSG00000168036 ENSG00000172936 ENSG00000079999 PMC5601168__F1 Wnt/Beta-catenin pathway in arrhythmogenic cardiomyopathy ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5601168__F2 Wnt/Beta-catenin pathway in arrhythmogenic cardiomyopathy ENSG00000186575 ENSG00000168036 ENSG00000057294 PMC3759561__F1 Regulation of Muscle Protein Synthesis and the Effects of Catabolic States PMC6265603__F3 Altered PI3K/Akt pathway during normal and insulin resistance ENSG00000147162 ENSG00000198408 PMC8688947__F1 High-Fat Diet-Induced Renal Proximal Tubular Inflammatory Injury: Emerging Risk Factor of Chronic Kidney Disease ENSG00000162711 ENSG00000135218 ENSG00000171720 ENSG00000105329 ENSG00000137033 ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000121807 ENSG00000128965 PMC6265603__F1 Model-based in silico analysis of the PI3K/Akt pathway: the elucidation of cross-talk between diabetes and breast cancer ENSG00000147162 ENSG00000141564 PMC6769682__F5 Receptors used by chemerin, visfatin, resistin and apelin for their signaling pathways ENSG00000174600 ENSG00000185483 PMC9001126__F7 Mesenchymal Stem Cells and their Derived Exosomes Promote Malignant Phenotype of Polyploid Non-Small-Cell Lung Cancer Cells through AMPK Signaling Pathway ENSG00000178860 ENSG00000100985 PMC8963304__F8 Profiling Secreted miRNA Biomarkers of Chemical-Induced Neurodegeneration in Human iPSC-Derived Neurons ENSG00000152266 ENSG00000019991 ENSG00000259207 ENSG00000100906 ENSG00000148400 ENSG00000086991 ENSG00000150093 ENSG00000168036 ENSG00000108654 ENSG00000112715 ENSG00000135446 ENSG00000123374 ENSG00000136160 ENSG00000185591 ENSG00000174059 ENSG00000151617 PMC3569837__F2 Understanding metabolic regulation and its influence on cell physiology ENSG00000180210 ENSG00000114268 ENSG00000078237 ENSG00000079999 PMC5930454__F8 miR-135b upregulated in BLBC represses multiple genes ENSG00000049323 ENSG00000087095 ENSG00000137834 ENSG00000101146 ENSG00000134982 ENSG00000156574 ENSG00000134363 ENSG00000205250 ENSG00000111537 ENSG00000100592 ENSG00000095739 ENSG00000100387 ENSG00000167941 ENSG00000113558 ENSG00000185269 PMC8232957__F1 Cholesterol Metabolism as a Potential Therapeutic Target and a Prognostic Biomarker for Cancer Immunotherapy ENSG00000089692 ENSG00000135218 ENSG00000126353 ENSG00000100219 ENSG00000100985 PMC5735743__F3 MTG16, and other MTG family members, may play a role in the constitutive repression of both Wnt and Notch signaling pathways ENSG00000198435 ENSG00000136997 ENSG00000168036 ENSG00000196628 PMC4816337__F1 Quantitative Modeling of the Alternative Pathway of the Complement System ENSG00000039537 ENSG00000203710 PMC5661630__F3 ZIP-mediated signaling pathways promote cell proliferation and metastasis in luminal and tamoxifen-resistant breast cancer cells ENSG00000291971 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC6151767__F27 Asymmetric aldol/lactonization sequence for the synthesis of spirooxindole dihydropyranones 93 ENSG00000090402 ENSG00000144857 ENSG00000104320 PMC2217489__F4 F igure 4 ENSG00000198793 PMC5661630__F2 Zinc deficiency in prostate cancer cells promotes cell survival via a phosphoinositide 3-kinase (PI3K) signaling pathway ENSG00000135446 ENSG00000132646 PMC3864108__F1 Schematic diagram showing the interaction between NW arenaviruses and host innate immune response ENSG00000174125 ENSG00000183735 ENSG00000172005 ENSG00000172936 ENSG00000131323 PMC6626595__F2 Biosynthesis pathway of sialylation ENSG00000064225 ENSG00000008513 ENSG00000111728 ENSG00000160408 ENSG00000070731 ENSG00000115525 ENSG00000126091 ENSG00000073849 ENSG00000095380 ENSG00000159921 ENSG00000170191 ENSG00000111726 ENSG00000101638 ENSG00000148488 ENSG00000070526 ENSG00000113532 ENSG00000144057 PMC8770421__F2 Versatility and paradox of BMP signaling in endothelial cell behaviors and blood vessel function ENSG00000121989 ENSG00000170365 ENSG00000137834 ENSG00000120693 ENSG00000204217 ENSG00000163217 ENSG00000114739 PMC6147150__F2 Pathway and network analyses showing major cellular processes associated with persistence of BD ENSG00000167553 ENSG00000186395 ENSG00000070831 ENSG00000134757 ENSG00000087586 ENSG00000081277 ENSG00000184363 ENSG00000166851 ENSG00000162999 ENSG00000140534 ENSG00000008083 ENSG00000291875 ENSG00000186081 ENSG00000135838 ENSG00000166263 ENSG00000186847 ENSG00000107186 ENSG00000137831 ENSG00000101213 ENSG00000104432 ENSG00000065357 ENSG00000178078 ENSG00000134762 ENSG00000163209 ENSG00000125384 ENSG00000137648 ENSG00000150764 ENSG00000167074 ENSG00000143228 ENSG00000186442 ENSG00000242372 ENSG00000128872 ENSG00000198901 ENSG00000169607 ENSG00000291754 ENSG00000122952 ENSG00000024526 ENSG00000168924 ENSG00000075218 ENSG00000112115 ENSG00000170477 ENSG00000127863 PMC3607076__F3 ATM controls cellular survival in response to DNA damage through multiple pathways ENSG00000149311 PMC12215033__F7 Schematic pathway illustrating the potential effect of curcumenol on Fc epsilon receptor I signaling ENSG00000033327 ENSG00000010810 ENSG00000010671 PMC3607076__F4 Selected summary of the ATM signaling network ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000163961 ENSG00000155827 ENSG00000080345 ENSG00000182923 ENSG00000291953 ENSG00000112130 PMC3983448__F4 Human epidermal growth receptor family members, the PI3K/Akt pathway, and targeted drugs ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC3042643__F1 EGFR signaling pathway ENSG00000146648 PMC3983448__F2 Molecular pathway for microsatellite instability+ gastric cancer ENSG00000117713 ENSG00000139546 ENSG00000196591 ENSG00000124571 ENSG00000121879 PMC2739295__F6 Gene Expression Profiling in Cells with Enhanced Gamma-Secretase Activity ENSG00000281324 ENSG00000162337 ENSG00000118785 ENSG00000026508 ENSG00000168036 ENSG00000196470 ENSG00000115718 PMC7774932__F7 Network pharmacology of bioactives from Sorghum bicolor with targets related to diabetes mellitus ENSG00000132170 PMC8282058__F6 Synaptic Vesicle Protein 2A Interacts With Key Pathogenic Factors in Alzheimer’s Disease: Implications for Treatment ENSG00000142192 ENSG00000197081 PMC7774932__F8 Network pharmacology of bioactives from Sorghum bicolor with targets related to diabetes mellitus ENSG00000132170 PMC3580541__F5 TRAF6 and TRAF2/5 signaling pathways ENSG00000082512 ENSG00000175104 ENSG00000127191 PMC7318778__F2 Dendritic cell metabolic reprogramming in tumor immune evasion ENSG00000168036 ENSG00000100219 ENSG00000038945 PMC3898101__F8 Separate PI3K and Wnt signaling pathways ENSG00000134982 ENSG00000168036 PMC8387852__F5 Gold nanoparticles enhance microRNA 31 detection in colon cancer cells after inhibition with chlorogenic acid PMC3697618__F7 Diagram illustrating the phagocytic signaling pathway initiated by TLR4-linked JAK2 activation during the internalization of B ENSG00000070831 ENSG00000170458 ENSG00000136869 PMC5282884__F7 Illustration of interaction between NRIP2, RORB, and HBP1 ENSG00000053702 ENSG00000168646 ENSG00000196628 ENSG00000069667 PMC7358640__F1 Main calcium signaling pathways through Ca2+ channels and transporters involved in the regulation of calcium homeostasis in mammalian cells ENSG00000092439 ENSG00000175938 ENSG00000167323 ENSG00000156026 ENSG00000109689 ENSG00000119121 ENSG00000133107 ENSG00000144935 ENSG00000293604 ENSG00000165125 ENSG00000137672 ENSG00000063180 ENSG00000138741 PMC10831399__F3 NRP-1 gene expression generating axis of stem-cell properties ENSG00000187772 PMC6099543__F7 Proposed biosynthetic pathway for nine ginsenosides ENSG00000180210 ENSG00000139687 PMC4237243__F4 PI3K/Akt/mTOR pathway inhibitors enhance radiosensitivity in radioresistant prostate cancer cells through inducing apoptosis, reducing autophagy, suppressing NHEJ and HR repair pathways ENSG00000188486 ENSG00000012048 ENSG00000051180 ENSG00000139618 PMC12020991__F9 Schematic diagram of the molecular mechanism of PEDV hijacking CD4+ T cells for migration to the intestinal mucosa ENSG00000099866 ENSG00000070831 PMC4888492__F1 Insulin signalling and glucose transport in the ovary and ovarian function during the ovarian cycle ENSG00000117020 ENSG00000002330 ENSG00000110395 ENSG00000005882 ENSG00000010810 ENSG00000150907 ENSG00000169047 ENSG00000146678 ENSG00000133124 PMC4888492__F2 Insulin signalling and glucose transport in the ovary and ovarian function during the ovarian cycle ENSG00000117020 ENSG00000163235 ENSG00000169047 ENSG00000198793 ENSG00000146678 PMC5665080__F2 Metabolic reprogramming associated with immune cell activation engages the mevalonate pathway ENSG00000131473 ENSG00000198793 ENSG00000026103 PMC5665080__F3 Inflammatory and immune responses to mevalonate pathway dysregulation ENSG00000110921 ENSG00000197429 PMC5665080__F1 SREBP-driven mevalonate pathway ENSG00000131473 ENSG00000160752 ENSG00000110921 ENSG00000112972 ENSG00000197429 ENSG00000113161 ENSG00000148459 ENSG00000167508 ENSG00000075239 PMC4237243__F5 PI3K/Akt/mTOR pathway inhibitors enhance radiosensitivity in radioresistant prostate cancer cells through inducing apoptosis, reducing autophagy, suppressing NHEJ and HR repair pathways ENSG00000188486 ENSG00000012048 ENSG00000198793 ENSG00000051180 ENSG00000139618 PMC4053348__F1 Role of MALT1 in signaling to NFKB in ABC DLBCL ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000172936 ENSG00000083799 ENSG00000131096 ENSG00000184216 ENSG00000010671 ENSG00000198286 PMC6595388__F7 Signaling pathway ENSG00000137275 ENSG00000102871 ENSG00000130159 ENSG00000168040 ENSG00000127191 PMC3992846__F2 Production of biosynthetic precursors during glycolytic metabolism and their putative regulation during Xenopus tail appendage regeneration ENSG00000059804 PMC4298731__F6 Cancer systems biology of TCGA SKCM: Efficient detection of genomic drivers in melanoma ENSG00000157404 ENSG00000107404 ENSG00000157764 ENSG00000182158 ENSG00000149782 ENSG00000169885 ENSG00000168036 ENSG00000169032 ENSG00000137841 ENSG00000087460 ENSG00000133216 ENSG00000049130 ENSG00000101440 ENSG00000104290 ENSG00000136160 ENSG00000080166 ENSG00000107165 PMC6028640__F1 Schematic overview of the pathway linking IMMP2L to senescence PMC7292335__F1 Cbl-B in T-cell activation ENSG00000163599 PMC4411085__F7 Converging mechanisms in ALS and FTD: Disrupted RNA and protein homeostasis ENSG00000165280 PMC7937869__F7 Coronavirus N protein inhibiting IFNB production ENSG00000183735 ENSG00000131323 ENSG00000121060 PMC2292467__F6 DNA replication and damage checkpoint regulation ENSG00000260314 ENSG00000132646 ENSG00000093009 PMC4411085__F5 Converging mechanisms in ALS and FTD: Disrupted RNA and protein homeostasis ENSG00000112367 ENSG00000188021 ENSG00000165280 PMC11053446__F6 KEGG pathway analysis for DE mRNAs from cTECs infected with IBV DMV/1639 or IBV Mass41 ENSG00000168040 ENSG00000150455 ENSG00000276561 ENSG00000143387 ENSG00000239732 ENSG00000105397 ENSG00000170458 ENSG00000141086 ENSG00000187554 ENSG00000136869 ENSG00000172936 ENSG00000175104 ENSG00000164342 PMC9120667__F1 Metabolism and Endocrine Disorders: What Wnt Wrong? ENSG00000281324 ENSG00000116729 ENSG00000162337 ENSG00000134982 ENSG00000126457 ENSG00000102312 ENSG00000168036 PMC8224327__F2 Anti-Angiogenic Property of Free Human Oligosaccharides ENSG00000128917 ENSG00000148400 ENSG00000138798 ENSG00000112715 ENSG00000146648 ENSG00000150630 PMC4258562__F1 Schematic presentation of the pathways involved in the inflammatory response during acute pancreatitis ENSG00000172936 ENSG00000136869 PMC1287678__F9 Putative signaling pathway of the evolutionarily conserved Toll/NFKB pathway utilizing the E ENSG00000130159 ENSG00000175104 PMC5429546__F4 KEGG analysis of upregulated and downregulated promoter DMGs showing involvement in a metabolic pathway ENSG00000152463 ENSG00000139133 ENSG00000123454 ENSG00000137825 ENSG00000099810 ENSG00000100033 ENSG00000131873 PMC7004536__F3 Alterations in the oncogenic pathways in 88 NSCLC cell lines other than the CUL3‐KEAP1‐NRF2 system ENSG00000124102 ENSG00000157764 ENSG00000198793 ENSG00000181555 ENSG00000049618 ENSG00000047936 ENSG00000117713 ENSG00000149311 ENSG00000135446 ENSG00000143622 ENSG00000139687 ENSG00000146648 ENSG00000196712 ENSG00000127616 ENSG00000189079 PMC7403894__F3 Suppressed anti-inflammatory heat shock response in high-risk COVID-19 patients: lessons from basic research (inclusive bats), light on conceivable therapies ENSG00000174125 ENSG00000162711 ENSG00000284774 ENSG00000130234 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000184216 PMC3547105__F1 The autotaxin-LPA-LPA1pathway ENSG00000173599 ENSG00000198670 PMC3782523__F1 Blocking the B7-H4 pathway with novel recombinant antibodies enhances T cell-mediated antitumor responses PMC9260869__F6 Downregulation of TNFR2 decreases survival gene expression, promotes apoptosis and affects the cell cycle of gastric cancer cells ENSG00000104237 ENSG00000102871 ENSG00000127191 PMC7403894__F1 Suppressed anti-inflammatory heat shock response in high-risk COVID-19 patients: lessons from basic research (inclusive bats), light on conceivable therapies ENSG00000174125 ENSG00000162711 ENSG00000284774 ENSG00000136869 ENSG00000096717 PMC3102606__F4 Pathway context for RME modules found in glioblastoma ENSG00000196136 ENSG00000148773 ENSG00000146648 ENSG00000196712 PMC2991311__F4 Systems Biology Approach Uncovers Cellular Strategies Used by Methylobacterium extorquens AM1 During the Switch from Multi- to Single-Carbon Growth ENSG00000261701 ENSG00000197713 ENSG00000122966 ENSG00000196839 ENSG00000172005 ENSG00000015285 ENSG00000231179 ENSG00000062485 ENSG00000084774 PMC7014913__F2 Pathogenic alpha-synuclein transmission ENSG00000069329 PMC6113245__F1 Biosynthesis pathway of HBGAs PMC2800957__F1 Targets for lithium’s neuroprotective effects ENSG00000002330 ENSG00000168036 PMC3492042__F8 MicroRNA targetome suggests aberrant upregulation of cell cycle regulators in AD brains ENSG00000145604 ENSG00000132646 ENSG00000115942 ENSG00000123374 ENSG00000164754 ENSG00000277273 ENSG00000276876 PMC11599740__F2 Activating insulin growth factors and energy deprivation triggers the HIF signaling pathway ENSG00000134086 ENSG00000147162 ENSG00000266173 ENSG00000169047 ENSG00000163914 ENSG00000196712 PMC3492042__F5 MicroRNA targetome suggests aberrant upregulation of T cell receptor signaling pathway molecules in ATL cells ENSG00000110395 ENSG00000213658 ENSG00000010810 ENSG00000113263 PMC8932107__F4 BDNF and TrKB expression levels in patients with endometriosis and their associations with dysmenorrhoea ENSG00000169291 PMC6862444__F2 GBM induction of PD-L1 secretion ENSG00000159128 ENSG00000115415 ENSG00000198793 ENSG00000027697 ENSG00000172936 ENSG00000175104 ENSG00000128564 ENSG00000146648 PMC4419223__F3 Green tea modulates the various cell signalling pathways in cancer PMC6880928__F1 Splicing the innate immune signalling in leukaemia ENSG00000172936 PMC4419223__F2 Role of green tea in cancer prevention through the modulation of genes involved in initiations, promotion, and progression of cancer ENSG00000171791 PMC3492042__F3 MicroRNA targetome suggests aberrant upregulation of cell cycle regulators in AD brains ENSG00000175054 ENSG00000276876 PMC10573510__F6 Asthma pathway ENSG00000134982 ENSG00000197971 PMC5964147__F7 HMGA1 exacerbates tumor growth through regulating the cell cycle and accelerates migration/invasion via targeting miR-221/222 in cervical cancer ENSG00000100234 ENSG00000087245 ENSG00000100985 PMC3196058__F2 Dynamic Role of Beta-Catenin in Synaptic Plasticity ENSG00000134982 ENSG00000084774 PMC6938674__F8 Targeting CDK7 for treating Yap/Taz-driven cancer ENSG00000101751 ENSG00000277273 ENSG00000166169 PMC3317271__F1 Simplified scheme of cell death and survival pathways involved in ALF ENSG00000047936 ENSG00000168040 ENSG00000127191 PMC8444356__F2 Fibrinogen-like protein 1 (FGL1): the next immune checkpoint target ENSG00000143799 ENSG00000262406 ENSG00000104760 ENSG00000138798 ENSG00000170558 ENSG00000198793 ENSG00000146648 PMC4864964__F1 Processes involved in generation of the T cell-inflamed tumor microenvironment phenotype ENSG00000169245 ENSG00000138755 PMC11918971__F7 Aerobic exercise (AE) stimulates the synthesis of anti-inflammatory “muscle factors” such as IL-6, IL-10, and IL-1ra through skeletal muscle contraction while reducing the activity of proinflammatory factors such as TNFA PMC4864964__F2 How tumor-intrinsic Beta-catenin signaling mediates exclusion of T cells from the tumor microenvironment ENSG00000168036 ENSG00000162772 ENSG00000277943 PMC8112849__F3 Melanogenesis signalling pathways ENSG00000168036 PMC3991209__F1 Diagram showing activation of Notch signalling ENSG00000135547 ENSG00000140564 ENSG00000148400 ENSG00000074181 ENSG00000114315 PMC8081528__F9 The mechanism of Txnip-mediated cone rescue ENSG00000143799 ENSG00000265972 PMC8163614__F1 B2-Adrenergic receptor agonism as a therapeutic strategy for kidney disease ENSG00000116688 ENSG00000171109 PMC8082854__F2 Metabolic adaptation mechanism of metastatic organotropism ENSG00000141448 ENSG00000115415 ENSG00000117118 ENSG00000198793 ENSG00000173599 ENSG00000198074 ENSG00000100033 ENSG00000070669 PMC8163614__F2 B2-Adrenergic receptor agonism as a therapeutic strategy for kidney disease ENSG00000126562 ENSG00000147099 PMC5752449__F6 Proteasome and ErbB signaling pathway ENSG00000111537 ENSG00000002330 ENSG00000110395 ENSG00000198793 ENSG00000177606 ENSG00000136997 ENSG00000198576 ENSG00000291973 ENSG00000132963 PMC7005787__F6 UPR activation and patient outcome in cancer ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC6275018__F3 Representative model of leptin-induced EMT signaling ENSG00000168610 PMC8836072__F3 Proliferation and Apoptosis Pathways and Factors in Oral Squamous Cell Carcinoma ENSG00000100290 ENSG00000002330 ENSG00000140379 ENSG00000120868 ENSG00000168040 ENSG00000135116 ENSG00000104081 PMC5752449__F4 Shared and specific mechanism of four autoimmune diseases ENSG00000144410 ENSG00000172936 ENSG00000131323 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000164342 ENSG00000143387 PMC5752449__F5 The shared and specific mechanism of four autoimmune diseases ENSG00000087245 ENSG00000033327 ENSG00000171105 ENSG00000002330 ENSG00000070831 ENSG00000113070 ENSG00000146648 ENSG00000084774 ENSG00000026103 PMC7215987__F1 Phosphoinositide 3-kinase-Akt-mammalian target of rapamycin (PI3K-Akt-mTOR) signaling pathway ENSG00000169047 ENSG00000198793 ENSG00000155792 ENSG00000164327 PMC7215987__F2 Main components and crosstalk between the Ras-Raf-mitogen-activated protein kinase-Ras- extracellular signal-regulated kinase (Ras-Raf-MEK-ERK) pathway, the spleen tyrosine kinase (SYK) pathway and the PI3K-Akt-mTOR pathway ENSG00000002330 ENSG00000291971 ENSG00000169047 ENSG00000155792 PMC7449758__F7 Proposed action model for the PI3K/AKT/FoxO3a pathway via ROS regulating DNA damage in the lung, liver, and kidney induced by Nano-TiO2 intratracheal administration ENSG00000116717 ENSG00000047936 PMC3674381__F7 Model of XIAP as a switch between type I and type II signaling PMC7468012__F1 Embryonic MTHFR contributes to blastocyst development ENSG00000284320 ENSG00000116984 PMC8077906__F1 Small molecule inhibitors against PD-1/PD-L1 immune checkpoints and current methodologies for their development: a review ENSG00000291603 ENSG00000198793 PMC3531868__F1 Receptors for IL4 and IL13 are comprised of four different subunits, IL4RA (green), gamma chain (Gc; purple), IL13RA1 (red), and IL13RA2 (yellow) ENSG00000113520 ENSG00000131724 PMC3512134__F6 Overall organization of mitotic exit control ENSG00000134982 ENSG00000117399 PMC7855837__F1 Elesclomol: a bis(thiohydrazide) amide compound that binds copper in a 1:1 ratio ENSG00000123454 ENSG00000137714 PMC4316689__F2 Activation of RAS–MAPK pathway induces expression of numerous genes, some of which can be targeted ENSG00000174567 ENSG00000115163 ENSG00000178999 ENSG00000087586 ENSG00000138160 ENSG00000196363 PMC2838081__F10 Molecular pathways regulated by C/EBPB during E-induced proliferation of uterine epithelial cells ENSG00000149311 ENSG00000175054 ENSG00000112242 ENSG00000070950 ENSG00000123374 PMC8229353__F1 Opposed Interplay between IDH1 Mutations and the WNT/Beta-Catenin Pathway: Added Information for Glioma Classification ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000168610 PMC8229353__F2 Opposed Interplay between IDH1 Mutations and the WNT/Beta-Catenin Pathway: Added Information for Glioma Classification ENSG00000127445 ENSG00000134982 ENSG00000168036 PMC4838196__F3 Phosphoproteome analysis links protein phosphorylation to cellular remodeling and metabolic adaptation during Magnaporthe oryzae appressorium development ENSG00000101082 ENSG00000152348 ENSG00000111305 ENSG00000146005 ENSG00000144848 ENSG00000145782 ENSG00000169299 ENSG00000057663 ENSG00000006007 ENSG00000114520 PMC7273358__F6 Metabolic rewiring of the hypertensive kidney ENSG00000176715 ENSG00000169710 ENSG00000141564 ENSG00000171791 ENSG00000124762 ENSG00000127884 ENSG00000163914 ENSG00000136997 ENSG00000136869 ENSG00000105552 ENSG00000128928 ENSG00000075239 ENSG00000105662 ENSG00000152266 ENSG00000113889 ENSG00000143549 ENSG00000142192 ENSG00000120699 ENSG00000099194 ENSG00000132693 ENSG00000132170 ENSG00000263243 ENSG00000137992 ENSG00000115263 ENSG00000112115 ENSG00000162692 ENSG00000146648 ENSG00000019991 ENSG00000162711 ENSG00000135218 ENSG00000105329 ENSG00000105550 ENSG00000198793 ENSG00000113161 ENSG00000120437 ENSG00000049768 ENSG00000112715 ENSG00000164305 ENSG00000163631 ENSG00000117054 ENSG00000130164 ENSG00000170266 ENSG00000113520 ENSG00000113790 ENSG00000091140 ENSG00000116044 ENSG00000073756 ENSG00000187134 ENSG00000102977 ENSG00000111537 ENSG00000120899 ENSG00000177606 ENSG00000161533 ENSG00000100985 ENSG00000122971 ENSG00000196689 PMC4167267__F7 Observed tumor patterns ENSG00000157554 ENSG00000157764 ENSG00000134982 ENSG00000138829 ENSG00000198793 ENSG00000153201 ENSG00000168036 ENSG00000181555 ENSG00000169032 ENSG00000167034 ENSG00000139618 ENSG00000079999 ENSG00000115524 ENSG00000150907 ENSG00000164362 ENSG00000131018 ENSG00000139687 ENSG00000196604 ENSG00000134909 ENSG00000196712 ENSG00000127616 ENSG00000271425 PMC8756109__F7 Vps34 Inhibits Hepatocellular Carcinoma Invasion by Regulating Endosome-Lysosome Trafficking via Rab7-RILP and Rab11 ENSG00000274145 ENSG00000146648 PMC2195768__F6 Proposed signaling pathway of the purinergic receptor: regulation of cardiac autonomic activity ENSG00000010810 ENSG00000135605 PMC6419954__F6 G-protein mediated effects on smooth muscle tone regulation ENSG00000095321 ENSG00000163914 ENSG00000132478 ENSG00000131095 ENSG00000123143 ENSG00000288461 PMC3953345__F2 Schematic presentation of the molecular mechanisms of myogenic differentiation ENSG00000111049 ENSG00000122180 ENSG00000135903 ENSG00000168036 ENSG00000005102 PMC5649202__F2 Gene regulatory network (GRN) inferred for members from the NFKB pathway ENSG00000095585 ENSG00000149311 ENSG00000163558 ENSG00000213341 ENSG00000100065 PMC9678096__F7 Capsaicin suppresses hepatocarcinogenesis by inhibiting the stemness of hepatic progenitor cells via SIRT1/SOX2 signaling pathway ENSG00000096717 PMC5649202__F4 Gene regulatory network (GRN) inferred for members from the TP53 pathway ENSG00000085117 ENSG00000175793 ENSG00000099860 ENSG00000118971 ENSG00000080546 ENSG00000149311 ENSG00000175054 ENSG00000048392 ENSG00000134574 ENSG00000078900 ENSG00000134057 ENSG00000130222 ENSG00000112378 ENSG00000120868 ENSG00000149547 ENSG00000026103 PMC4633791__F1 Activation of effector and regulatory T cells by antigen presenting cells ENSG00000134982 ENSG00000049768 PMC4633791__F3 Induction of cell lines of spy cells into functionally distinct Treg lines ENSG00000134982 ENSG00000137265 ENSG00000049768 PMC4633791__F4 Newly recruited CD4+ T-cell soldiers induced to be spies ENSG00000134982 ENSG00000049768 PMC4633791__F5 Activated and aggressive CD4+T cell soldiers convert to spies ENSG00000049768 ENSG00000026103 PMC3974997__F2 Interference with the host NFKB signaling pathways by STPKs of pathogenic bacteria: LegK1, OspG, and NleH1 ENSG00000104856 ENSG00000149273 ENSG00000099942 PMC4489880__F5 When pathways collide: collaboration and connivance among signaling proteins in development ENSG00000186575 ENSG00000139926 ENSG00000164690 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC5723694__F7 TNFAlpha-senescence initiates a STAT-dependent positive feedback loop, leading to a sustained interferon signature, DNA damage, and cytokine secretion ENSG00000111537 ENSG00000115415 ENSG00000168610 PMC4489880__F4 When pathways collide: collaboration and connivance among signaling proteins in development ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC4252843__F5 PROTEASE MEDIATED HUMAN SMOOTH MUSCLE CELL PROLIFERATION BY UROKINASE REQUIRES EPIDERMAL GROWTH FACTOR RECEPTOR TRANSACTIVATION BY TRIPLE MEMBRANE SIGNALING ENSG00000113070 ENSG00000137845 ENSG00000146648 ENSG00000148848 PMC2202913__F1 Control of Food Intake by the Hypothalamic Leptin-Melanocortin PathwayThe hypothalamus receives and integrates neural, metabolic, and hormonal signals to regulate energy homeostasis ENSG00000198576 ENSG00000115138 PMC4489880__F1 When pathways collide: collaboration and connivance among signaling proteins in development ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5723694__F3 TNFAlpha-senescence initiates a STAT-dependent positive feedback loop, leading to a sustained interferon signature, DNA damage, and cytokine secretion ENSG00000068079 ENSG00000213928 ENSG00000111537 ENSG00000033800 ENSG00000185745 ENSG00000125347 PMC4489880__F2 When pathways collide: collaboration and connivance among signaling proteins in development ENSG00000291971 PMC6302376__F5 Regulatory relationships between genes in a signal pathway regulating the TP53 gene ENSG00000149311 PMC5667558__F1 microRNAs and lipid metabolism ENSG00000128918 ENSG00000107798 ENSG00000160179 ENSG00000145782 ENSG00000132356 ENSG00000057663 ENSG00000081923 PMC7069501__F3 Therapeutic targeting of trained immunity ENSG00000162711 ENSG00000135218 ENSG00000167207 ENSG00000125538 ENSG00000198793 PMC8138124__F1 New Faces of old Friends: Emerging new Roles of RNA-Binding Proteins in the DNA Double-Strand Break Response ENSG00000143799 ENSG00000083093 ENSG00000138346 ENSG00000110107 ENSG00000141499 ENSG00000147274 ENSG00000139618 ENSG00000112130 ENSG00000149311 ENSG00000012048 ENSG00000163961 ENSG00000092208 ENSG00000197299 ENSG00000051180 PMC9694773__F1 The Pathogenesis of Acute Porphyria Attacks and Increasing Hepatic PBGD as an Etiological Treatment ENSG00000144410 ENSG00000126088 ENSG00000188690 PMC8123490__F4 Metabolic Spectrum of Liver Failure in Type 2 Diabetes and Obesity: From NAFLD to NASH to HCC ENSG00000042832 ENSG00000134013 ENSG00000121807 PMC7415776__F1 Metabolic rewiring of cyanobacterial central metabolism with a synthetic acetate‐acetyl‐CoA/malonyl‐CoA (AAM) bypass for improved photosynthetic production of acetone from CO2 ENSG00000159224 ENSG00000186063 ENSG00000172005 PMC2836122__F2 Cytokine signaling through the JAK/STAT pathway ENSG00000159128 ENSG00000115415 ENSG00000027697 ENSG00000128342 ENSG00000168610 ENSG00000142166 PMC9227908__F4 Metabolic Reprogramming in Cancer Cells: Emerging Molecular Mechanisms and Novel Therapeutic Approaches ENSG00000198793 ENSG00000169710 ENSG00000136003 ENSG00000159399 PMC9227908__F1 Metabolic Reprogramming in Cancer Cells: Emerging Molecular Mechanisms and Novel Therapeutic Approaches ENSG00000136997 ENSG00000153574 ENSG00000078237 PMC6485631__F1 CD69: from activation marker to metabolic gatekeeper ENSG00000105639 PMC9099129__F3 Natural killer cells in liver transplantation: Can we harness the power of the immune checkpoint to promote tolerance? ENSG00000291603 PMC6643109__F3 In T2 DM rats, where the Hepatic Glucokinase (HGK) is lower, the level of lncRNA NONRATT021972 is increased PMC3254042__F7 Signaling pathways involved in synaptic plasticity and neuroglia functions with associated molecules and cellular tasks (analysis based on Ingenuity IPA software) ENSG00000157764 ENSG00000138798 ENSG00000198793 PMC5070717__F1 GSK3B in TLR4 responses ENSG00000183735 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC5022960__F4 Regulating signal pathway related to gastric lipase (LIPF) and diacylglycerol kinase A (DGKA) in gastric cancer (GC) ENSG00000065357 ENSG00000182333 ENSG00000172216 ENSG00000129152 PMC5070717__F2 GSK3B in TLR3 signaling ENSG00000183735 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC4575837__F2 Dietary restriction, mitochondrial function and aging: from yeast to humans ENSG00000142082 PMC7877093__F11 Five genes are indicated in red on the AGE–RAGE signaling pathway map after PGQYD treatment (red) ENSG00000087245 ENSG00000042832 ENSG00000135446 ENSG00000007908 PMC9097084__F9 Transcriptional Profiling of Resistant and Susceptible Cultivars of Grapevine (Vitis L.) Reveals Hypersensitive Responses to Plasmopara viticola ENSG00000105722 PMC3531794__F1 Impact of IL-27 on lymphocyte signaling pathways ENSG00000186810 ENSG00000105397 ENSG00000115415 ENSG00000107485 ENSG00000105246 ENSG00000168610 ENSG00000106546 PMC6835611__F7 Inflammatory signaling pathway and the resulting downstream responses ENSG00000100985 ENSG00000162692 PMC7418786__F3 Growth Factor Receptor Signaling Inhibition Prevents SARS-CoV-2 Replication ENSG00000102606 ENSG00000120915 ENSG00000291971 ENSG00000198561 ENSG00000106299 ENSG00000115904 ENSG00000162302 ENSG00000196396 ENSG00000168610 ENSG00000124356 ENSG00000089159 ENSG00000063245 ENSG00000115977 ENSG00000110395 ENSG00000172939 ENSG00000165912 ENSG00000160584 ENSG00000141086 ENSG00000122705 ENSG00000076641 ENSG00000127527 ENSG00000146648 ENSG00000105287 PMC4314215__F4 MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy ENSG00000169554 ENSG00000041982 ENSG00000136997 ENSG00000124766 PMC5233753__F1 Schematized general estrogen signaling pathway ENSG00000198793 ENSG00000168036 PMC4646278__F8 Overview of the role of pioglitazone activated PPARG and ROCK inhibition on survival of dissociated single hPSCs ENSG00000168036 PMC6766413__F4 μOR regulation of CXCR4 working modelMorphine or other μ-opioids binding to μORs on cortical neurons activates a GAi-protein pathway that leads to de-acidification of endolysosomes, and efflux of endolysosomal iron to the cytoplasm ENSG00000106683 ENSG00000107562 ENSG00000149269 ENSG00000121966 PMC9613808__F2 Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics ENSG00000162711 ENSG00000276561 ENSG00000010671 ENSG00000142166 ENSG00000239732 ENSG00000088888 ENSG00000130234 ENSG00000263528 ENSG00000184012 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC6562674__F1 Hedgehog signaling pathway ENSG00000106571 ENSG00000128602 PMC7057977__F5 COAD “cyan” module APOL6 subnetwork ENSG00000173821 ENSG00000169248 ENSG00000187608 ENSG00000183486 ENSG00000157601 ENSG00000232326 ENSG00000230034 ENSG00000137959 ENSG00000068079 ENSG00000135899 ENSG00000132530 ENSG00000168062 ENSG00000133106 ENSG00000163840 ENSG00000156587 ENSG00000078081 ENSG00000134326 ENSG00000002549 ENSG00000140464 ENSG00000132109 ENSG00000117228 ENSG00000115267 ENSG00000185745 ENSG00000205220 ENSG00000125347 ENSG00000162654 ENSG00000276561 ENSG00000184979 ENSG00000169245 ENSG00000067066 ENSG00000224320 ENSG00000115415 ENSG00000156127 ENSG00000013374 ENSG00000138642 ENSG00000010030 ENSG00000128335 ENSG00000111331 PMC7540116__F1 Metformin inhibits cancer invasion and migration via AMPK signaling pathway ENSG00000155792 ENSG00000140443 PMC7540116__F2 Metformin inhibits cancer invasion and migration by blocking EMT signaling pathway ENSG00000169554 ENSG00000198793 ENSG00000168610 PMC7540116__F3 Metformin inhibiting cancer invasion and migration ENSG00000198793 ENSG00000136997 ENSG00000168610 PMC4659166__F7 Network of interactions between GWAS candidate genes using ingenuity pathway analysis (IPA) ENSG00000116641 ENSG00000143156 ENSG00000101639 ENSG00000122778 ENSG00000116991 ENSG00000150457 ENSG00000125676 ENSG00000148484 ENSG00000131023 ENSG00000143375 ENSG00000130224 ENSG00000148396 PMC5757216__F1 Circadian clocks: from stem cells to tissue homeostasis and regeneration ENSG00000108924 ENSG00000105516 ENSG00000005812 ENSG00000132326 ENSG00000167074 ENSG00000112378 PMC3110863__F4 Regulation of MeCP2 expression by Bdnf PMC3927937__F2 Mixed-lineage leukemia ENSG00000122025 ENSG00000141867 ENSG00000134982 ENSG00000168036 PMC9178375__F2 Gut microbes and muscle function: can probiotics make our muscles stronger? ENSG00000177169 ENSG00000169047 ENSG00000131096 ENSG00000140443 PMC9477829__F1 Exosome biosynthesis and uptake pathways ENSG00000168461 ENSG00000135404 PMC8889587__F6 Aberrant protein S-nitrosylation in ER stress-mediated insulin resistance ENSG00000128272 ENSG00000144895 ENSG00000196839 PMC3744831__F2 DDR-adapted model in meiotic silencing ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000054796 PMC5188458__F1 Potential Links between Impaired One-Carbon Metabolism Due to Polymorphisms, Inadequate B-Vitamin Status, and the Development of Alzheimer’s Disease PMC7569438__F10 Molecular mechanism by which Guttiferone K exerts anti-inflammatory effects in Mtb-infected macrophages ENSG00000162711 ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC1874671__F2 Genomic organization of the CDKN2A locus and description of involvement of its transcripts (p16INK4a and p14ARF) in the Rb and p53 pathways ENSG00000135446 ENSG00000105810 PMC2754694__F1 Transcriptional regulation of human CYP17 ENSG00000291971 ENSG00000169375 PMC6125039__F1 Human and yeast peroxisomal Beta-oxidation pathways ENSG00000242110 ENSG00000276559 ENSG00000107537 ENSG00000018510 ENSG00000161533 ENSG00000173208 ENSG00000116906 ENSG00000197601 ENSG00000128513 PMC4584349__F1 Metabolites of the folate cycle, transsulfuration pathway, and methionine (Met)-homocysteine (Hcy) cycle ENSG00000173599 ENSG00000116761 PMC11084589__F2 Inhibition of pathway activity induces microglial cell state transition ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC11084589__F3 Increased pathway activity induces a shift from a neurotoxic to a neuroprotective state in microglia ENSG00000164879 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC11084589__F4 Possible targeting pathway of ABA in PD ENSG00000110931 ENSG00000172936 ENSG00000136869 PMC11611323__F2 Metabolism of AdA ENSG00000196839 ENSG00000105516 PMC8084697__F1 Type I and III Interferons in COVID-19 ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000134321 ENSG00000187608 ENSG00000105397 ENSG00000115415 ENSG00000130234 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000164342 PMC11611323__F3 Action of AdA in NAFLD ENSG00000135218 ENSG00000196839 PMC6857111__F5 Coexpression network was constructed by WGCNA ENSG00000029363 ENSG00000152409 ENSG00000164904 ENSG00000138433 ENSG00000153201 ENSG00000164190 ENSG00000163736 ENSG00000043093 ENSG00000115464 ENSG00000145604 ENSG00000112977 ENSG00000039319 ENSG00000171848 ENSG00000113263 ENSG00000183054 ENSG00000257315 ENSG00000116649 ENSG00000169629 ENSG00000164619 ENSG00000187627 ENSG00000132341 PMC11913683__F4 CAT has anti-osteoporotic effects through other pathways ENSG00000008710 ENSG00000111537 ENSG00000167468 ENSG00000171791 ENSG00000096717 ENSG00000140465 ENSG00000168610 PMC7359092__F1 Recent discoveries on the protective role of IL-22 against tissue injury ENSG00000105550 ENSG00000198793 ENSG00000171791 ENSG00000168610 ENSG00000143954 PMC9325512__F1 CMTM6 and CMTM7: New leads for PD‐L1 regulation in breast cancer cells undergoing EMT ENSG00000124216 ENSG00000115009 PMC3612515__F3 Graphical representation of Ingenuity Pathway Analysis results showing considerable overlap of the significantpredictor genes in the significant biologic pathways ENSG00000152782 ENSG00000162627 ENSG00000154764 ENSG00000132938 ENSG00000105835 ENSG00000157764 ENSG00000142798 ENSG00000170027 ENSG00000197905 ENSG00000107863 ENSG00000205250 ENSG00000158169 ENSG00000172216 ENSG00000077420 ENSG00000150907 ENSG00000139842 ENSG00000105204 PMC4263413__F1 Transcriptome Profiles of the Protoscoleces of Echinococcus granulosus Reveal that Excretory-Secretory Products Are Essential to Metabolic Adaptation PMC11913683__F2 Mechanisms by which CAT promotes osteoblast differentiation ENSG00000170365 ENSG00000008710 ENSG00000163221 ENSG00000198793 ENSG00000120693 ENSG00000164690 ENSG00000096717 ENSG00000128602 PMC11913683__F3 CAT inhibition of osteoclast differentiation ENSG00000170909 ENSG00000077463 ENSG00000131196 ENSG00000143387 PMC3612515__F1 Graphical representation of Ingenuity Pathway Analysis results showing significant predictors genes in ‘Gene Expression, Cell Cycle, Cancer’ pathway ENSG00000152782 ENSG00000163564 ENSG00000168395 ENSG00000170540 ENSG00000080819 ENSG00000291803 ENSG00000141639 ENSG00000126457 ENSG00000100442 ENSG00000075223 ENSG00000164615 ENSG00000051180 ENSG00000107731 ENSG00000120471 ENSG00000122779 ENSG00000136108 PMC8495591__F4 Blood glucose control contributes to protein stability of Ski-related novel protein N in a rat model of diabetes PMC3612515__F2 Graphical representation of Ingenuity Pathway Analysis results showing significant predictor genes in ‘InflammatoryResponse, Cell Death, Infection Mechanism’ pathway ENSG00000163564 ENSG00000168395 ENSG00000170540 ENSG00000123066 ENSG00000204463 ENSG00000112659 ENSG00000100442 ENSG00000177426 ENSG00000075223 ENSG00000131238 ENSG00000198924 ENSG00000100387 ENSG00000107731 ENSG00000120471 ENSG00000112893 ENSG00000122779 ENSG00000109670 PMC4754720__F4 Metabolic regulation of mitochondrial transport and mitophagy ENSG00000177169 ENSG00000147162 ENSG00000069509 ENSG00000247077 PMC4441389__F5 Fractionated Ionizing Radiation Promotes Epithelial-Mesenchymal Transition in Human Esophageal Cancer Cells through PTEN Deficiency-Mediated Akt Activation PMC7199713__F1 Herbal medicine on the intrinsic pathway of apoptosis ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC7199713__F2 Herbal medicine on the extrinsic pathway of apoptosis ENSG00000102871 ENSG00000123374 ENSG00000172936 ENSG00000168040 ENSG00000026103 PMC4597337__F5 Molecular Mechanisms for High Hydrostatic Pressure-Induced Wing Mutagenesis in Drosophila melanogaster ENSG00000069869 ENSG00000133961 PMC6450213__F5 Gene network on chemokine signaling pathway by KEGG analysis of module-related DEGs ENSG00000156299 ENSG00000291971 ENSG00000149269 ENSG00000113263 PMC2740411__F8 Transcriptional regulation of cell cycle arrest gene p21 by ZBTB5 ENSG00000183337 ENSG00000185591 PMC3977821__F6 Robustness and Plasticity of Metabolic Pathway Flux among Uropathogenic Isolates of Pseudomonas aeruginosa ENSG00000143252 ENSG00000073578 ENSG00000117118 PMC6425710__F1 Pericytes contribute in homeostasis of the BBB through different mechanisms ENSG00000128917 ENSG00000291971 ENSG00000074181 ENSG00000170558 ENSG00000086991 ENSG00000077782 PMC6425710__F2 Under pathologic circumstances, pericytes present stemness or trans-differentiation potential ENSG00000026508 ENSG00000131095 ENSG00000205927 ENSG00000174059 ENSG00000162692 PMC3418731__F3 Signaling within the JAK-STAT pathway in bovine monocytes and M ENSG00000100385 ENSG00000115008 ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000168610 ENSG00000142166 ENSG00000168685 PMC8297548__F2 TIRAP in the Mechanism of Inflammation ENSG00000174125 ENSG00000134070 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000010671 PMC5820622__F2 Depiction of classical and nonclassical pathway to NF-kB (p65-p50 or RelBp52) translocation activation ENSG00000104856 ENSG00000102871 ENSG00000172936 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000127191 ENSG00000106829 PMC5472670__F1 The UPR signaling pathways ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC5512418__F7 The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity ENSG00000172936 ENSG00000150457 ENSG00000131023 PMC1326326__F3 Proposed regulation of Cdc25A at the G1 and intra-S-phase checkpoints ENSG00000149311 ENSG00000175054 ENSG00000123374 PMC12105201__F8 SLC3A2 and SLC7A5 in the pathogenesis of OA ENSG00000168003 ENSG00000198793 ENSG00000103257 PMC4259987__F2 Pathway analysis (STRING v9.05) of 39 proteins significantly dysregulated in the CSF of subjects with mild or moderate delirium relative to the mild AD control with no delirium ENSG00000121552 ENSG00000142192 ENSG00000189058 ENSG00000104112 ENSG00000149294 ENSG00000163453 ENSG00000120885 ENSG00000163815 ENSG00000113905 ENSG00000132692 ENSG00000158874 ENSG00000167755 ENSG00000171560 ENSG00000089199 PMC3835199__F4 = Transporter, ◊ = Enzyme, ∇ = Kinase, ∆ = Phosphatase, = Transcription regulator, 〇 = Other, = Complex/group, = Peptidase ENSG00000166579 ENSG00000171100 ENSG00000078369 ENSG00000197102 ENSG00000178531 ENSG00000151849 ENSG00000143458 ENSG00000197386 ENSG00000143493 ENSG00000054118 ENSG00000106459 PMC7078196__F6 Lipoic acid decreases breast cancer cell proliferation by inhibiting IGF-1R via furin downregulation ENSG00000140564 ENSG00000140443 PMC8773838__F2 Janus Kinase Signaling Pathway and Its Role in COVID-19 Inflammatory, Vascular, and Thrombotic Manifestations ENSG00000105639 PMC3674867__F1 Plasminogen Activator Inhibitor-1: The Double Edged Sword in Apoptosis PMC8469138__F6 Molecular Biology Networks and Key Gene Regulators for Inflammatory Biomarkers Shared by Breast Cancer Development: Multi-Omics Systems Analysis ENSG00000138378 ENSG00000069482 ENSG00000105397 ENSG00000148400 ENSG00000100979 ENSG00000127955 ENSG00000168610 PMC5467823__F6 Brain-derived neurotrophic factor (BDNF) -TrKB signaling modulates cancer-endothelial cells interaction and affects the outcomes of triple negative breast cancer ENSG00000169071 ENSG00000136378 ENSG00000140379 ENSG00000154485 ENSG00000145194 ENSG00000134007 ENSG00000139985 ENSG00000163638 ENSG00000087116 ENSG00000073670 ENSG00000136688 PMC6952436__F1 Exhaustion and senescence: two crucial dysfunctional states of T cells in the tumor microenvironment ENSG00000291603 ENSG00000156127 ENSG00000198793 ENSG00000123374 PMC4594353__F1 Characteristics, regulators and effects of the epithelial-mesenchymal transition (EMT) ENSG00000170558 ENSG00000168036 PMC3565216__F1 Phosphatidic Acid Plays a Central Role in the Transcriptional Regulation of Glycerophospholipid Synthesis in Saccharomyces cerevisiae ENSG00000163624 ENSG00000146005 ENSG00000173599 ENSG00000166123 PMC7859098__F4 m6A modification in immune-related bone homeostasis ENSG00000152266 ENSG00000112715 ENSG00000175104 ENSG00000165819 PMC9021207__F2 Associated immune metabolism in the tumor microenvironment ENSG00000118520 PMC9563138__F2 Metabolic Pathways in Breast Cancer Reprograming: An Insight to Non-Coding RNAs ENSG00000131473 ENSG00000113161 ENSG00000104549 ENSG00000169710 PMC4354380__F1 Polycomb and trithorax proteins regulate chromatin structure and gene expression ENSG00000198901 ENSG00000230797 ENSG00000096717 PMC5104533__F2 An Immunological Perspective on Neonatal Sepsis ENSG00000084093 ENSG00000125538 PMC8458393__F8 Wuzi-Yanzong prescription alleviates spermatogenesis disorder induced by heat stress dependent on Akt, NFKB signaling pathway ENSG00000167601 ENSG00000092445 ENSG00000172936 ENSG00000187266 PMC7426447__F2 Signal transduction of ginseng gintonin on the mammalian cell plasma membrane via LPA receptors, GPR40, and GPR55 ENSG00000198670 PMC8486193__F4 Reactive oxygen species in cancer: Current findings and future directions ENSG00000198793 ENSG00000120868 ENSG00000168040 ENSG00000026103 PMC7426447__F4 Signaling pathway for gintonin-mediated autophagic influx via LPA1 receptor ENSG00000198793 ENSG00000197386 ENSG00000057663 PMC5372489__F3A Systematic Study of Dysregulated MicroRNA in Type 2 Diabetes Mellitus ENSG00000171105 ENSG00000288174 ENSG00000169047 ENSG00000105647 PMC8922318__F5 Identification of the Potential Key Genes and Pathways Involved in Lens Changes of High Myopia ENSG00000087095 ENSG00000170458 ENSG00000149269 ENSG00000130159 ENSG00000101224 ENSG00000115718 ENSG00000175104 ENSG00000127191 ENSG00000081189 ENSG00000026103 PMC8922318__F6 Identification of the Potential Key Genes and Pathways Involved in Lens Changes of High Myopia ENSG00000124102 ENSG00000182533 ENSG00000041982 ENSG00000130528 ENSG00000156026 ENSG00000186716 PMC7991738__F1 Apoptosis regulation via Cl− channels in ESCC cell ENSG00000119397 ENSG00000001626 ENSG00000114859 ENSG00000185101 PMC9371493__F8 Active compounds and molecular mechanism of Xuefu Zhuyu decoction for atherosclerosis, based on network pharmacology and molecular docking ENSG00000087245 ENSG00000127445 ENSG00000007908 ENSG00000168610 PMC11729014__F13 Mechanism of action of NCOA4-mediated ferritinophagy-induced ferroptosis promoting endothelial injure ENSG00000164430 ENSG00000162692 PMC3438185__F9 Novel Levamisole Derivative Induces Extrinsic Pathway of Apoptosis in Cancer Cells and Inhibits Tumor Progression in Mice ENSG00000168040 ENSG00000026103 PMC10377123__F3 Pharmacological Potential of Betulin as a Multitarget Compound ENSG00000178573 ENSG00000023909 ENSG00000106546 ENSG00000079999 PMC11279831__F1 IL-36 signaling pathway ENSG00000196136 ENSG00000141527 ENSG00000152056 ENSG00000136694 PMC8665538__F5 Comparative analysis of aneurysm subtypes associated genes based on protein–protein interaction network ENSG00000162711 ENSG00000150782 ENSG00000137757 ENSG00000125538 ENSG00000196954 ENSG00000142405 PMC4211323__F1 Possible roles of Hsp90 in AD ENSG00000136869 PMC9530810__F5 Comprehensive analysis of m6A-modified circRNAs in peritoneal metastasis of high grade serious carcinoma of ovary ENSG00000172680 ENSG00000169291 ENSG00000170458 ENSG00000198517 ENSG00000158104 ENSG00000088926 ENSG00000134548 ENSG00000026103 PMC6306698__F6 Pharmacological regulation of pluripotency circuitry establishment during cellular reprogramming via the FEN-stimulated PPARA regulatory pathway PMC4549768__F1 DNA damage tolerance mechanisms ENSG00000130997 ENSG00000051180 ENSG00000178966 PMC4549768__F2 Regulation of DNA damage tolerance by proliferating cell nuclear antigen modification ENSG00000132646 ENSG00000070950 ENSG00000130997 PMC3843373__F4 The PI3K pathway is the evolutionary conserved signalling pathway to ensure that growth and development is synchronised to the appropriate metabolic conditions: energy and substrate requiring processes only proceed when a ‘fed state’ is indicated ENSG00000002330 ENSG00000198793 PMC7682023__F5 Schematic depicting genes in the PLC signalling pathway ENSG00000197943 ENSG00000137841 ENSG00000284017 PMC9026965__F1 Vitamin D Impacts on Skeletal Muscle Dysfunction in Patients with COPD Promoting Mitochondrial Health ENSG00000126858 ENSG00000198793 ENSG00000158828 ENSG00000096717 ENSG00000171109 ENSG00000062485 ENSG00000214253 PMC9026965__F2 Vitamin D Impacts on Skeletal Muscle Dysfunction in Patients with COPD Promoting Mitochondrial Health ENSG00000171109 PMC10385528__F3 Anticancer mode of action of melittin on the essential molecular targets in different carcinomas ENSG00000087245 ENSG00000168610 PMC3700115__F7 Known and novel roles of the p38-MK2/3 signaling pathway in cross-striated muscles ENSG00000185591 ENSG00000106459 PMC5026795__F1 Recognition of C. albicans by pattern recognition receptors ENSG00000125538 ENSG00000172005 ENSG00000113520 ENSG00000136869 PMC9421066__F2 Crosstalk between sonodynamic therapy and autophagy in cancer ENSG00000177169 ENSG00000123395 ENSG00000198793 ENSG00000144848 ENSG00000148572 ENSG00000145782 ENSG00000057663 PMC2519092__F2 Cellular responses after six hours exposure to L ENSG00000163624 ENSG00000224320 ENSG00000170893 ENSG00000102977 PMC9409683__F1 Regulatory Roles of Estrogens in Psoriasis ENSG00000157554 PMC7035921__F3 miRNA regulation of miR-155 upon mycobacterial infection and dual role of miR-155 in the survival of mycobacteria ENSG00000144848 ENSG00000172936 ENSG00000136869 ENSG00000156273 PMC8611092__F3 Crosstalk between circRNAs and the PI3K/AKT signaling pathway in cancer progression ENSG00000140262 ENSG00000174963 ENSG00000155363 PMC8611092__F4 Crosstalk between circRNAs and the PI3K/AKT signaling pathway in cancer progression ENSG00000198793 ENSG00000150093 ENSG00000140443 PMC8611092__F2 Crosstalk between circRNAs and the PI3K/AKT signaling pathway in cancer progression ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000102104 PMC8611092__F5 Crosstalk between circRNAs and the PI3K/AKT signaling pathway in cancer progression ENSG00000116962 PMC9672132__F1 Investigation of the physiological response of radiation-induced cystitis patients using hyperbaric oxygen ENSG00000143799 ENSG00000115008 ENSG00000107562 ENSG00000242689 ENSG00000160181 ENSG00000112715 ENSG00000073756 ENSG00000007171 ENSG00000180210 ENSG00000185652 ENSG00000177606 ENSG00000125538 ENSG00000113520 PMC3380339__F1 Cross-regulation between the IL-1B/IL-18 processing inflammasome and other inflammatory cytokines ENSG00000179331 ENSG00000088888 ENSG00000187796 ENSG00000163568 ENSG00000125538 ENSG00000189403 ENSG00000115009 PMC4395390__F3 Exploring Triacylglycerol Biosynthetic Pathway in Developing Seeds of Chia (Salvia hispanica L.): A Transcriptomic Approach ENSG00000182511 ENSG00000169710 ENSG00000152767 ENSG00000280548 ENSG00000026103 PMC10304248__F2 Mycobacterium tuberculosis and apoptosis modulation ENSG00000102871 ENSG00000168040 PMC10304248__F3 Mycobacterium tuberculosis and the necrotic-like cell death modulation ENSG00000278718 ENSG00000162711 ENSG00000167207 ENSG00000137275 ENSG00000102871 ENSG00000119383 ENSG00000127191 ENSG00000123576 ENSG00000167468 ENSG00000157625 ENSG00000172936 ENSG00000168404 ENSG00000175104 ENSG00000285379 ENSG00000184216 PMC3313983__F5 Associations between HIV and Human Pathways Revealed by Protein-Protein Interactions and Correlated Gene Expression Profiles ENSG00000115415 ENSG00000163235 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC7379134__F8 Schematic diagram showing the crosstalk of the ASK1-JNK1/2 pathway and ER stress during DICD ENSG00000002330 ENSG00000144895 ENSG00000100219 ENSG00000171791 ENSG00000127191 PMC9554302__F2 Advances in RIPK1 kinase inhibitors ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 PMC7158602__F7 The functions of OMT on inhibiting NP cells inflammation ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC7641301__F7 Over-regulated pathway after 48 h Forskolin stimulation ENSG00000160789 ENSG00000177606 ENSG00000178209 ENSG00000167658 PMC8874497__F2 Lipid Metabolism and Epigenetics Crosstalk in Prostate Cancer ENSG00000131473 ENSG00000135218 ENSG00000130164 ENSG00000100412 ENSG00000113161 ENSG00000026103 ENSG00000133027 PMC2998553__F3 Screen shot of the user interfaceofSimmune2.0 ENSG00000291603 ENSG00000213658 PMC4133513__F1 Toll-like receptor signalling ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC2912611__F8 From HLA-B27 to spondyloarthritis: a journey through the ER ENSG00000162594 PMC8262388__F6 Interplay Between Mitochondrial Reactive Oxygen Species, Endoplasmic Reticulum Stress, and Nrf2 Signaling in Cardiometabolic Health ENSG00000128272 ENSG00000105550 ENSG00000130513 PMC2808058__F3 The effects of SOX4 and HOXC6 on Notch pathway activation and metastasis ENSG00000156076 ENSG00000041982 ENSG00000148400 ENSG00000050165 ENSG00000124766 ENSG00000104332 ENSG00000137845 PMC2808058__F1 Schematic of the Notch pathway ENSG00000148400 ENSG00000069812 ENSG00000137845 PMC2808058__F2 The effects of the SOX4 and HOXC6 transcriptional networks on PI3K-AKT pathway activation in prostate cancer ENSG00000066468 ENSG00000197081 ENSG00000148400 ENSG00000124766 ENSG00000168036 ENSG00000146648 PMC7916951__F1 Multiple intracellular pathways triggered by Cytomegalovirus (CMV) and Epstein–Barr virus (EBV) infection converge on expression of proinflammatory cytokines and type I Interferon (IFN) response genes ENSG00000164430 ENSG00000172936 ENSG00000168310 ENSG00000131323 ENSG00000175104 ENSG00000276561 PMC1201514__F1 Regulation of the PIS1-encoded Phosphatidylinositol Synthase in Saccharomyces cerevisiae by Zinc ENSG00000163624 ENSG00000146005 PMC7858668__F2 Complement cascade and complement targeting therapies ENSG00000039537 ENSG00000197635 ENSG00000291559 ENSG00000117335 ENSG00000244731 ENSG00000166278 ENSG00000236625 PMC3268389__F1 Pathways and compartmentation of FA supply for TAG synthesis in plants ENSG00000173599 ENSG00000026103 PMC3096054__F1 miRNA biogenesis pathways and regulatory networks ENSG00000092847 ENSG00000134698 ENSG00000123908 PMC7858668__F1 Complement in diabetic kidney disease ENSG00000062485 PMC6856008__F6 MicroRNA Regulatory network with miRs from the anti-survival/EMT group ENSG00000172380 ENSG00000134982 ENSG00000188064 ENSG00000181104 ENSG00000269335 ENSG00000115904 ENSG00000173039 ENSG00000174804 ENSG00000150455 ENSG00000112715 ENSG00000095739 ENSG00000166501 ENSG00000056558 ENSG00000183579 ENSG00000197943 ENSG00000136869 ENSG00000285485 ENSG00000077782 ENSG00000140443 ENSG00000168772 ENSG00000168685 PMC5089367__F5 Targeted interactome of microRNAs (miRs) (miR-30c and miR-331-3p) PMC7020042__F6 Schematic diagram showing D and DA on adipocyte differentiation through GSK-3B/Beta-catenin signaling in ASCs ENSG00000245848 ENSG00000134982 ENSG00000168036 ENSG00000105723 ENSG00000026103 PMC5128196__F1 Huntington's disease pathway from KEGG database ENSG00000084093 ENSG00000188992 ENSG00000130699 ENSG00000185591 ENSG00000169375 ENSG00000164305 PMC6341806__F2 Summarized molecular pathway of BDNF/TrkB's oncogenic role ENSG00000168610 ENSG00000146648 PMC3443857__F1 Progesterone regulated paracrine signaling model depicted within the uterine compartments at the time of embryo implantation ENSG00000162552 ENSG00000164107 ENSG00000163501 PMC8469858__F1 Therapeutic Targeting of the Gas6/Axl Signaling Pathway in Cancer ENSG00000167601 PMC7015852__F6 Water lily genome and the early evolution of flowering plants ENSG00000214513 ENSG00000205221 ENSG00000128513 PMC4076981__F8 Schematic drawing of the current model for the interrelationship between nutrient and light signaling in T ENSG00000078369 ENSG00000146247 PMC7675406__F3 Leukocyte trafficking to the lungs and beyond: lessons from influenza for COVID-19 ENSG00000108691 ENSG00000110799 ENSG00000121807 PMC8814673__F2 Advances in research on the effects of platelet activation in acute lung injury (Review) ENSG00000291971 PMC5173167__F1 Signal transducer and activator of transcription 3 in myeloid-derived suppressor cells: an opportunity for cancer therapy ENSG00000108691 ENSG00000107562 ENSG00000125538 ENSG00000173599 ENSG00000136997 ENSG00000118520 ENSG00000100985 PMC4479818__F1 Folate metabolic pathway ENSG00000228716 ENSG00000100714 ENSG00000124275 ENSG00000116984 PMC5584302__F2 PD1 signal transduction pathways in T cells ENSG00000291603 ENSG00000078747 ENSG00000123374 ENSG00000163631 PMC8710012__F1 Hippo signaling pathway in leukemia: function, interaction, and carcinogenesis ENSG00000109321 ENSG00000136997 ENSG00000107485 ENSG00000150457 ENSG00000131023 PMC4939890__F2 Pathophysiological mechanisms involved in bicuspid aortic valve (BAV) ENSG00000154342 ENSG00000125398 ENSG00000162337 ENSG00000148400 PMC3705329__F1 SMAD/BMP pathway in hepatocytes ENSG00000010704 ENSG00000106327 PMC8710012__F4 Hippo signaling pathway in leukemia: function, interaction, and carcinogenesis ENSG00000136807 ENSG00000150457 ENSG00000131023 PMC5378358__F6 Transcriptome analysis of Corynebacterium glutamicum in the process of recombinant protein expression in bioreactors ENSG00000122966 ENSG00000173599 ENSG00000172005 PMC7300268__F1 Regulation of YAP/TAZ ENSG00000087095 ENSG00000167601 ENSG00000126016 ENSG00000186575 ENSG00000156299 ENSG00000089685 ENSG00000144560 ENSG00000136997 ENSG00000168036 ENSG00000007047 ENSG00000131023 PMC8161467__F7 Enhanced G1 arrest and apoptosis via MDM4/MDM2 double knockdown and MEK inhibition in wild-type TP53 colon and gastric cancer cells with aberrant KRAS signaling ENSG00000026103 ENSG00000198625 PMC7606690__F4 Nef-mediated activation of Itk requires Nef homodimers ENSG00000113263 PMC8720622__F7 LncRNA LINC00460: Function and mechanism in human cancer ENSG00000138764 ENSG00000173120 ENSG00000168036 PMC7352793__F6 ncRNAs involved in the IR-induced Wnt/Beta-catenin pathway ENSG00000168036 ENSG00000182916 PMC2254178__F1 Vital Elements of the Wnt-Frizzled Signaling Pathway in the Nervous System ENSG00000134982 ENSG00000168036 PMC8863344__F2 Reciprocal regulation of cellular mechanics and metabolism ENSG00000132109 ENSG00000291971 ENSG00000163914 PMC3570203__F2 Genes highly expressed in TNBC compared to HR-positive, HER2-negative breast cancer ENSG00000262406 ENSG00000115163 ENSG00000178999 ENSG00000131747 ENSG00000101057 ENSG00000166851 ENSG00000117399 ENSG00000117724 ENSG00000206075 ENSG00000138778 ENSG00000148773 ENSG00000024526 ENSG00000013810 ENSG00000127824 ENSG00000149554 ENSG00000112742 PMC3129465__F2 Genetic dissection of eosinophilic esophagitis provides insight into disease pathogenesis and treatment strategies ENSG00000105329 ENSG00000145777 ENSG00000006606 ENSG00000143631 ENSG00000134987 PMC3636031__F9 Early Apoptosis of Macrophages Modulated by Injection of Yersinia pestis YopK Promotes Progression of Primary Pneumonic Plague ENSG00000168040 ENSG00000175104 PMC9204334__F1 Molecular Role of IL-35 in Non-Small Cell Lung Cancer ENSG00000115415 ENSG00000168036 ENSG00000105246 ENSG00000049768 ENSG00000168610 PMC6468848__F2 The Notch signaling pathway ENSG00000132964 PMC6417835__F3 Architecture of the Fanconi anemia (FA) core complex, with FAAPs (Fanconi anemia–associated proteins) indicated by numbers ENSG00000077152 ENSG00000181544 ENSG00000187790 ENSG00000115392 ENSG00000187741 ENSG00000112039 ENSG00000158169 PMC6468848__F3 Functional effects of Notch-regulated miRNAs in glioblastoma ENSG00000198382 ENSG00000148400 ENSG00000090932 PMC6417835__F4 Roles of FA proteins in replication stress ENSG00000138346 ENSG00000077152 ENSG00000187790 ENSG00000115392 ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000166508 ENSG00000139618 ENSG00000012048 ENSG00000175054 ENSG00000175643 ENSG00000197299 ENSG00000051180 PMC10840486__F9 Schematic illustration showing synergistic calcium supplementation and SIM delivery strategy for osteoporosis ENSG00000117525 PMC6468848__F4 Other Notch-related tumorigenic aspects in the pathogenesis of Glioblastoma ENSG00000159167 ENSG00000092439 ENSG00000168036 ENSG00000176165 ENSG00000172201 ENSG00000128965 PMC8002742__F3 The NLRP3 inflammasome pathway ENSG00000162711 ENSG00000150782 ENSG00000125538 PMC8185253__F11 Assessment of Significant Pathway Signaling and Prognostic Value of GNG11 in Ovarian Serous Cystadenocarcinoma ENSG00000136457 ENSG00000135218 ENSG00000110799 ENSG00000149308 ENSG00000026508 ENSG00000152592 PMC3624769__F1 Interferon (IFN)-Gamma-activated pronecrotic and prosurvival signaling pathways ENSG00000115415 ENSG00000168040 ENSG00000168404 PMC8536488__F1 Cancer and Covid-19: Collectively catastrophic ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000168610 PMC6471380__F1 Molecular mechanisms of insulin functions and associated modifications in the hypothalamus ENSG00000128272 ENSG00000115138 ENSG00000164327 ENSG00000136869 ENSG00000168610 PMC6858945__F1 Outline of the molecular pharmacology and response determinants of clinical TOP1 inhibitors ENSG00000175054 ENSG00000172716 ENSG00000149554 ENSG00000042088 PMC8002742__F1 The activation of the Toll-like receptor signaling pathway ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000276561 ENSG00000164342 PMC3309175__F7 Mammalian target of rapamycin (mTOR) signaling pathway for the regulation of skeletal muscle protein synthesis in response to growth factors, nutrition, and mechanical stimuli ENSG00000198793 ENSG00000167658 PMC8002742__F2 Activation of type I interferon production via endosomal Toll-like receptors and RNA sensor signaling pathway in Sjögren’s syndrome ENSG00000183735 ENSG00000239732 ENSG00000088888 ENSG00000172936 ENSG00000131323 ENSG00000110057 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC4970451__F1 Migration of opioid-containing immune cells and opioid release within inflamed tissue ENSG00000125538 ENSG00000169429 PMC6237962__F3 Results of significant canonical pathways associated with ion-transport and the molecules involved ENSG00000175054 ENSG00000198626 PMC6237962__F4 RNA sequencing-based analysis of the laying hen uterus revealed the novel genes and biological pathways involved in the eggshell biomineralization ENSG00000291971 ENSG00000001626 ENSG00000095794 PMC8704918__F2 CWI Pathway: A Versatile Toolbox to Arrest Cell-Cycle Progression ENSG00000260314 PMC8503187__F1 Biased Ghrelin Receptor Signaling and the Dopaminergic System as Potential Targets for Metabolic and Psychological Symptoms of Anorexia Nervosa ENSG00000198576 ENSG00000115138 ENSG00000166603 PMC2769253__F3 MicroRNAs in cancer ENSG00000112242 ENSG00000136997 ENSG00000282899 PMC3137003__F2 The insulin and leptin-melanocortin signaling pathway is responsible for maintaining energy and metabolic balance by controlling appetite ENSG00000115138 ENSG00000166603 PMC2769253__F1 MicroRNAs in cancer ENSG00000113360 PMC8163825__F2 Key metabolic pathways in Hermodarchaeota genomes ENSG00000172005 ENSG00000038002 PMC8997791__F2 Interplay between Autophagy and Redox Signaling in Cardiovascular Diseases ENSG00000198793 ENSG00000057663 ENSG00000079999 PMC3433932__F3 The scheme summarizes the stretch-induced pathway that allows ROS scavenging in response to mechanical stimuli ENSG00000096717 PMC6639758__F3 An example of autocrine and paracrine interactions between NPY neuron (blue) and POMC neuron (green) in the ARC and their downstream effector neuron (i.e., neuron in PVN; beige) ENSG00000115138 ENSG00000124089 PMC2818158__F1 Inflammation at a molecular level: a simplified scheme ENSG00000172005 ENSG00000136869 ENSG00000164342 PMC5314324__F5 Activating Akt1 mutations alter DNA double strand break repair and radiosensitivity ENSG00000108106 ENSG00000062485 PMC2315691__F1 Complement system and complement regulatory proteins (CRegs) ENSG00000291559 ENSG00000203710 ENSG00000166278 PMC12217925__F8 CDH17-mediated regulation of LGR5 expression, Wnt signaling and drug resistance ENSG00000079112 ENSG00000165556 ENSG00000136997 ENSG00000017483 ENSG00000118777 ENSG00000133216 PMC4253612__F3 Genes in cancer-related pathways ENSG00000077150 ENSG00000291971 ENSG00000134982 ENSG00000169136 ENSG00000136997 ENSG00000168036 ENSG00000100985 ENSG00000146648 PMC4881561__F4 Notch signaling pathway and the localization of NSD1, BAP1, PDE4DIP and ATP10B in mesothelial cells ENSG00000118322 ENSG00000178104 PMC6142509__F1 Activation and regulation of the alternative complement pathway ENSG00000274619 ENSG00000000971 PMC5258846__F1 Microtubule motors drive Hedgehog signaling in primary cilia ENSG00000106571 ENSG00000166813 ENSG00000128602 PMC5155223__F6 Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma ENSG00000171943 ENSG00000266028 PMC1939900__F6 Different signaling pathway mediated by A3(IV)NC1 ENSG00000198793 ENSG00000173039 PMC4965087__F2 Pathways Underlying Distinct Cell Death Mechanisms in Two Human Lung Cancer Cell Lines in Response to SN1 Methylating Agents Treatment ENSG00000132906 ENSG00000002330 ENSG00000116717 ENSG00000196470 ENSG00000164305 ENSG00000175054 ENSG00000113328 ENSG00000048392 ENSG00000138764 ENSG00000136997 ENSG00000123374 ENSG00000112378 ENSG00000140743 ENSG00000026103 PMC2582809__F1 Role of cytokines in DC and T-cell interactions ENSG00000162594 ENSG00000134982 ENSG00000049768 PMC9709755__F3 Transcriptome profiling of colorectal tumors from patients with sepsis reveals an ethnic basis for viral infection risk and sepsis progression ENSG00000105193 ENSG00000198793 ENSG00000197728 ENSG00000138326 ENSG00000141564 ENSG00000164305 ENSG00000264424 ENSG00000197702 ENSG00000156475 ENSG00000280858 ENSG00000125691 ENSG00000077150 ENSG00000104140 ENSG00000108830 ENSG00000092054 ENSG00000197958 ENSG00000163017 ENSG00000177600 ENSG00000259207 ENSG00000005339 ENSG00000115221 ENSG00000161970 ENSG00000197616 ENSG00000104408 ENSG00000160691 ENSG00000078304 ENSG00000172809 ENSG00000106617 ENSG00000128272 ENSG00000142541 ENSG00000112640 PMC3109603__F7 Comparative pathway networks of cyclic genes in mouse, chicken and zebrafish ENSG00000204335 ENSG00000198435 ENSG00000120875 ENSG00000273529 ENSG00000114315 ENSG00000168646 ENSG00000125968 ENSG00000165617 ENSG00000127863 ENSG00000140807 ENSG00000158050 PMC12027552__F7 Correlation network diagram of differentially expressed genes (DEGs) and differentially accumulated metabolites (DAMs) in the plant hormone signal transduction pathway under the FR treatment ENSG00000110934 ENSG00000221818 PMC6540516__F8 Evolution of erlotinib resistance in CD166+ OSCs ENSG00000122691 ENSG00000146648 PMC3997714__F1 Autophagy is involved in the initiation of hepatocarcinoma (HCC) ENSG00000144895 ENSG00000198793 PMC9019486__F3 miR-874: An Important Regulator in Human Diseases ENSG00000107562 ENSG00000134982 ENSG00000008196 ENSG00000168036 ENSG00000150457 ENSG00000132964 ENSG00000128602 ENSG00000168610 ENSG00000131023 ENSG00000164104 PMC4279367__F1 Under physiological conditions, ERK signaling is regulated by extracellular signals binding to receptor tyrosine kinases (RTKs) ENSG00000135446 ENSG00000198793 ENSG00000139687 ENSG00000196712 PMC9692680__F5 Network Pharmacology- and Molecular Dynamics Simulation-Based Bioprospection of Aspalathus linearis for Type-2 Diabetes Care ENSG00000171105 ENSG00000166501 ENSG00000173039 ENSG00000146648 ENSG00000159399 PMC9644706__F3 FADD as a key molecular player in cancer progression ENSG00000171791 ENSG00000168040 PMC6281268__F9 Gene expression profiling of spontaneously occurring canine mammary tumours: Insight into gene networks and pathways linked to cancer pathogenesis ENSG00000173599 PMC6300493__F2 WW domain protein roles in genomic stability ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000155827 ENSG00000078747 PMC6281268__F6 Gene expression profiling of spontaneously occurring canine mammary tumours: Insight into gene networks and pathways linked to cancer pathogenesis ENSG00000149311 ENSG00000175054 ENSG00000276876 PMC6281268__F7 Gene expression profiling of spontaneously occurring canine mammary tumours: Insight into gene networks and pathways linked to cancer pathogenesis ENSG00000115760 ENSG00000084774 ENSG00000115317 ENSG00000026103 PMC6281268__F8 Gene expression profiling of spontaneously occurring canine mammary tumours: Insight into gene networks and pathways linked to cancer pathogenesis ENSG00000226275 ENSG00000111962 PMC6300493__F7 E3 modulate breast cancer cell invasion and metastasis ENSG00000078747 ENSG00000198742 ENSG00000138798 ENSG00000146648 ENSG00000121966 ENSG00000123124 PMC6431671__F7 Integrative pathway enrichment analysis showing the interaction between predicted and experimental targets ENSG00000164742 ENSG00000113905 ENSG00000117601 ENSG00000151655 ENSG00000167658 ENSG00000175899 ENSG00000168036 ENSG00000164167 ENSG00000055955 ENSG00000112715 ENSG00000229314 PMC6300493__F6 E3 ligases regulate breast cancer cell proliferation ENSG00000132471 ENSG00000126016 ENSG00000281324 ENSG00000162337 ENSG00000078747 ENSG00000198742 ENSG00000123124 PMC6300493__F4 Inactivation of the Hippo pathway induces breast cancer metastasis ENSG00000157933 ENSG00000073350 ENSG00000138443 ENSG00000114978 ENSG00000241058 ENSG00000143322 ENSG00000007047 ENSG00000131023 PMC5519339__F2 CREB-induced IL-10 production is regulated by IFNG ENSG00000185591 PMC3365841__F16 GPCR-modulated channel activity in pituitary cells ENSG00000157554 ENSG00000291972 ENSG00000253506 ENSG00000146469 ENSG00000170893 PMC7399097__F3 Interleukin-17A signaling transduction pathway ENSG00000196843 ENSG00000002330 ENSG00000157625 ENSG00000175104 ENSG00000127191 ENSG00000215301 ENSG00000163702 ENSG00000076604 ENSG00000084774 PMC4309263__F6 Schematic representation of the reciprocal auto-sustaining loop between Jagged1 ligand and Notch3 receptor in T-ALL ENSG00000148400 ENSG00000074181 ENSG00000137845 PMC3365841__F11 Pituitary cells express GPCRs that engage the cAMP signaling pathway ENSG00000291972 ENSG00000146469 ENSG00000166278 ENSG00000157005 PMC2872116__F1 Analysis of a protein interaction network in the context of the T-cell pathway ENSG00000177606 ENSG00000188130 ENSG00000162924 PMC2872116__F2 Structuring protein interactions around familiar canonical pathways provides intuitive visualizations ENSG00000149308 ENSG00000162924 ENSG00000132341 PMC11577955__F8 Mechanisms underlying the tryptophan metabolic pathway ENSG00000262635 ENSG00000183077 ENSG00000091140 PMC5841164__F1 PTEN signaling in Treg cells ENSG00000134982 ENSG00000150907 ENSG00000049768 PMC11411235__F4 Functions of tetraspanins in PC ENSG00000117472 ENSG00000156298 ENSG00000291971 ENSG00000071889 ENSG00000127324 ENSG00000100985 ENSG00000168610 ENSG00000150630 PMC11411235__F5 Functions of tetraspanins in CRC ENSG00000117472 ENSG00000106025 ENSG00000011105 ENSG00000168785 ENSG00000000003 ENSG00000127324 PMC11411235__F2 Functions of tetraspanins in GC ENSG00000137673 ENSG00000117472 ENSG00000011105 ENSG00000168785 ENSG00000135452 ENSG00000127324 ENSG00000146648 PMC11411235__F3 Functions of tetraspanins in liver cancer ENSG00000117472 ENSG00000156298 ENSG00000135446 ENSG00000168785 ENSG00000099282 ENSG00000135452 ENSG00000127324 ENSG00000100985 ENSG00000148848 PMC4667402__F2 Comprehensive illustration of transcription changes in skeletal muscle of red cusk-eel under handling stress using modified KEGG pathway maps using Pathvisio v3 ENSG00000105048 ENSG00000130939 ENSG00000275679 ENSG00000143549 ENSG00000198382 ENSG00000083290 ENSG00000163902 ENSG00000291973 ENSG00000140416 ENSG00000150991 ENSG00000136842 ENSG00000129152 ENSG00000145782 ENSG00000198947 PMC3110626__F1 Frequent genetic abnormalities of the PI3K/AKT pathway in primary ovarian cancer predict patient outcome ENSG00000103479 ENSG00000117020 ENSG00000002330 ENSG00000196455 ENSG00000198793 ENSG00000164362 ENSG00000105647 ENSG00000121879 ENSG00000171608 PMC9136039__F6 Pan-Cancer Single-Cell Analysis Reveals the Core Factors and Pathway in Specific Cancer Stem Cells of Upper Gastrointestinal Cancer ENSG00000163464 ENSG00000160180 ENSG00000134982 ENSG00000163734 ENSG00000169429 ENSG00000162896 PMC10135467__F2 Illustration of the regulatory network of METTL3 in the nervous system ENSG00000174576 ENSG00000198576 ENSG00000129245 ENSG00000268041 ENSG00000175104 ENSG00000090932 PMC8750188__F3 Identification of Let-7 miRNA Activity as a Prognostic Biomarker of SHH Medulloblastoma ENSG00000131914 ENSG00000187772 PMC8566343__F10 Comprehensive Proteome and Acetyl-Proteome Atlas Reveals Molecular Mechanisms Adapting to the Physiological Changes From Pre-laying to Peak-Laying Stage in Liver of Hens (Gallus gallus) ENSG00000180210 ENSG00000196839 ENSG00000138777 ENSG00000113790 ENSG00000174611 ENSG00000084774 ENSG00000005469 PMC9582773__F2 Glutathione deficiency in the pathogenesis of SARS-CoV-2 infection and its effects upon the host immune response in severe COVID-19 disease ENSG00000239732 ENSG00000184012 ENSG00000005381 ENSG00000132693 ENSG00000079999 PMC2933676__F3 The canonical Wnt signaling pathway ENSG00000124479 ENSG00000162337 ENSG00000168036 ENSG00000167074 PMC6369205__F11 Regulatory role of GRK2 in TLRs-mediated signaling pathways for iNOS expression in microglial cells ENSG00000239732 ENSG00000115415 ENSG00000136869 ENSG00000125347 ENSG00000168610 ENSG00000164342 PMC9355054__F1 Systematic review: Molecular docking simulation of small molecules as anticancer non-small cell lung carcinoma drug candidates ENSG00000138798 ENSG00000146648 PMC3364993__F5 Transactivation of EGFR by LPS Induces COX-2 Expression in Enterocytes ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC9323107__F2 Need for Individualized Risk Assessment in Cardiovascular Disease ENSG00000003436 ENSG00000122194 PMC8469784__F8 Melatonin and Phytomelatonin: Chemistry, Biosynthesis, Metabolism, Distribution and Bioactivity in Plants and Animals—An Overview PMC5372366__F4 Molecular Therapy for Degenerative Disc Disease: Clues from Secretome Analysis of the Notochordal Cell-Rich Nucleus Pulposus ENSG00000113140 ENSG00000197746 PMC9664769__F5 Disinfectant dodecyl dimethyl benzyl ammonium chloride (DDBAC) disrupts gut microbiota, phospholipids, and calcium signaling in honeybees (Apis mellifera) at an environmentally relevant level ENSG00000182533 ENSG00000198947 PMC9575643__F2 Cellular, molecular, metabolic and epigenetic approaches to studying trained immunity ENSG00000125538 ENSG00000136869 PMC6791490__F3 Evaluating Chemicals for Thyroid Disruption: Opportunities and Challenges with in Vitro Testing and Adverse Outcome Pathway Approaches ENSG00000174417 ENSG00000165409 ENSG00000170893 ENSG00000106546 PMC4543340__F1 HGF/MET signaling pathway ENSG00000019991 ENSG00000033327 PMC8790411__F1 Biomarkers for response to immune checkpoint inhibitors in gastrointestinal cancers ENSG00000138336 ENSG00000138755 ENSG00000177084 PMC3791171__F4 Molecular pathogenesis and mechanisms of thyroid cancer ENSG00000157764 ENSG00000042832 ENSG00000165409 PMC3791171__F1 Molecular pathogenesis and mechanisms of thyroid cancer ENSG00000100234 ENSG00000105329 ENSG00000165409 ENSG00000262217 ENSG00000112715 PMC3791171__F2 Molecular pathogenesis and mechanisms of thyroid cancer ENSG00000198793 ENSG00000168036 PMC4658327__F1 Nutrient-deprived cancer cells preferentially use sialic acid to maintain cell surface glycosylation ENSG00000159921 ENSG00000135838 ENSG00000100473 ENSG00000147162 ENSG00000145321 ENSG00000102032 ENSG00000146648 PMC4252768__F2 Wnt5a: A Player in the Pathogenesis of Atherosclerosis and other Inflammatory Disorders ENSG00000169071 ENSG00000168610 PMC9706101__F2 Serum and glucocorticoid-regulated kinase 1: Structure, biological functions, and its inhibitors ENSG00000162594 ENSG00000126562 ENSG00000102908 ENSG00000150907 ENSG00000118515 PMC4252768__F1 Wnt5a: A Player in the Pathogenesis of Atherosclerosis and other Inflammatory Disorders ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC3593299__F1 Ghrelin neuroprotective pathways in Parkinson’s disease ENSG00000177169 ENSG00000198793 ENSG00000158828 ENSG00000121853 ENSG00000175567 PMC3816228__F2 Receptors involved in allergen recognition and uptake by AECs ENSG00000145777 ENSG00000136869 ENSG00000146648 ENSG00000115009 PMC5831949__F3 Key biological pathways with DNB genes in cytokine-cytokine receptor interaction and PPAR signaling pathway ENSG00000090402 ENSG00000138798 ENSG00000274736 ENSG00000121807 ENSG00000142224 ENSG00000123999 ENSG00000150991 ENSG00000131142 ENSG00000145623 ENSG00000135960 ENSG00000122756 ENSG00000117400 ENSG00000175189 ENSG00000128052 ENSG00000291837 ENSG00000128342 ENSG00000056736 ENSG00000104432 ENSG00000026103 ENSG00000104899 ENSG00000112964 ENSG00000099985 ENSG00000145777 ENSG00000226275 ENSG00000108691 ENSG00000113494 PMC9126461__F1 Comparative BRAF V600E immunohistochemical expression in differentiated thyroid tumors with papillary features ENSG00000068028 ENSG00000157764 PMC5796257__F1 Deregulated frizzled (FZD) in Wnt/Beta-catenin signaling ENSG00000125398 ENSG00000105656 ENSG00000168036 PMC7981598__F5 Description of 3 overlapping-pathways for complement activation: The complement: opsonin C3b, anaphylatoxins C3a and C5a (complement peptides), and membrane-attack complex (MAC, C5b-9), produced by all three pathways ENSG00000166278 PMC8543968__F6 Activation of the EGFR-PI3K-CaM pathway by PRL-1-overexpressing placenta-derived mesenchymal stem cells ameliorates liver cirrhosis via ER stress-dependent calcium ENSG00000167323 ENSG00000135446 ENSG00000156026 ENSG00000146648 PMC6188668__F7 Arid5a in the IL-17R signaling pathway ENSG00000196843 ENSG00000144802 ENSG00000172216 ENSG00000127191 ENSG00000163702 PMC9470149__F2 The CCL2-CCR2 axis in cardiovascular disease: Pathogenesis and clinical implications ENSG00000108691 ENSG00000198793 ENSG00000121807 ENSG00000105639 PMC9010225__F2 Emerging role of PARP-1 and PARthanatos in ischemic stroke ENSG00000227345 PMC2947178__F8 Model for the Coordinated Action of the Mating Types to Regulate Different Stages of Pathogenic Development of U ENSG00000172409 ENSG00000180644 PMC10989365__F6 CALD1 facilitates epithelial-mesenchymal transition progression in gastric cancer cells by modulating the PI3K-Akt pathway ENSG00000122786 PMC8789681__F1 Resistance to Dopamine Agonists in Pituitary Tumors: Molecular Mechanisms ENSG00000163914 ENSG00000133112 PMC5927358__F1 Canonical Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000183579 ENSG00000108375 PMC7981598__F2 Status of mannose-binding lectin (MBL) and complement system in COVID-19 patients and therapeutic applications of antiviral plant MBLs ENSG00000175054 ENSG00000130234 PMC5927358__F3 Wnt/TOR and Wnt/STOP signaling pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC5671492__F7 Biphasic concentration-dependent regulation of Cav-1 gene expression and GSK-3B activity by fluoxetine in astrocytes ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC5831797__F2 Schematic depiction of the cross-talk between Hh signaling and DYRK kinases ENSG00000157540 ENSG00000106571 ENSG00000172005 ENSG00000128602 ENSG00000127334 ENSG00000105204 PMC6771624__F5 KEGG pathways for TCA cycle and retinol metabolism in the T 6 vs ENSG00000121207 ENSG00000284807 ENSG00000100412 ENSG00000140505 ENSG00000292155 ENSG00000101365 PMC7397755__F1 Lineage plasticity in cancer: a shared pathway of therapeutic resistance ENSG00000136997 ENSG00000136352 ENSG00000146648 ENSG00000139687 PMC8979719__F7 Comparison of Three Species of Rhubarb in Inhibiting Vascular Endothelial Injury via Regulation of PI3K/AKT/NFKB Signaling Pathway ENSG00000087245 ENSG00000157404 ENSG00000291971 ENSG00000198793 ENSG00000087586 ENSG00000171791 ENSG00000112715 ENSG00000121879 ENSG00000073756 ENSG00000168610 ENSG00000007171 ENSG00000132170 ENSG00000163631 ENSG00000108839 ENSG00000164362 ENSG00000102996 ENSG00000100985 ENSG00000005381 ENSG00000146648 ENSG00000127948 PMC7476343__F1 Representation of the reciprocal links between cancer and thrombosis ENSG00000110799 ENSG00000134982 ENSG00000173599 PMC6144451__F7 The effects of CLN3, flupirtine, retigabine, and benzyl (compound 5) or allyl (compound 6) carbamate derivatives on ceramide synthesis and intrinsic/extrinsic apoptotic pathways ENSG00000261832 ENSG00000172292 ENSG00000168040 ENSG00000168350 ENSG00000143418 ENSG00000026103 PMC4744706__F2 Key players of the mTOR complex1 cascade in LR asymmetry Cartoon depicting a simplified model of the TORC1‐dependent signalling pathway and its physiological outcome ENSG00000177169 ENSG00000126775 PMC9317563__F1 Plasmacytoid Dendritic Cells, a Novel Target in Myeloid Neoplasms ENSG00000167601 ENSG00000162711 ENSG00000198053 ENSG00000291971 ENSG00000163568 ENSG00000163599 ENSG00000198793 ENSG00000171791 ENSG00000196628 ENSG00000010671 ENSG00000095585 ENSG00000144485 ENSG00000239732 ENSG00000181847 ENSG00000136997 ENSG00000269404 ENSG00000136869 ENSG00000139687 ENSG00000164342 ENSG00000139193 ENSG00000101751 ENSG00000169554 ENSG00000140968 ENSG00000276561 ENSG00000149311 ENSG00000169249 ENSG00000115524 ENSG00000172936 ENSG00000131323 ENSG00000175104 PMC5795054__F1 Scheme of the biosynthetic pathway downstream to phenylalanine ENSG00000171759 PMC5336482__F2 Involvement of GSK3 in TLR4 signaling pathways.Activation of TLR4 by LPS or alarmins (called ligand in the figure) involves dimers of TLR4 binding to CD14 and MD-2 ENSG00000183735 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 PMC3407815__F1 The interleukin (IL)-12/IL-23/interferon (IFN)G pathway and its role in mycobacterial disease control ENSG00000115415 ENSG00000140968 PMC9179367__F1 Supplemental Nicotinic Acid Elevates NAD+ Precursors in the Follicular Fluid of Mares ENSG00000105835 ENSG00000278488 ENSG00000262217 PMC8067156__F2 Pathophysiology of Ulcerative Colitis ENSG00000169245 ENSG00000163739 ENSG00000137265 ENSG00000163734 ENSG00000107485 ENSG00000169429 ENSG00000049768 PMC8502484__F1 Parallels Between the Antiviral State and the Irradiated State ENSG00000213928 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000115415 ENSG00000163568 ENSG00000172936 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC9467317__F4 TI2-induced subnetwork ENSG00000132906 ENSG00000142192 ENSG00000173894 ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000115718 ENSG00000164305 PMC9065611__F5 Data of RNA-seq transcriptomes of liver, bone, heart, kidney and blood in klotho mice at a pre-symptomatic state and the effect of a traditional Japanese multi-herbal medicine, juzentaihoto ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000158578 ENSG00000256269 ENSG00000188690 PMC8434535__F11 Protective Effects of Sal B on Oxidative Stress-Induced Aging by Regulating the Keap1/Nrf2 Signaling Pathway in Zebrafish ENSG00000173992 ENSG00000181019 ENSG00000198517 ENSG00000116791 ENSG00000128829 ENSG00000142082 ENSG00000106459 ENSG00000156273 PMC11705637__F4 Main pathways involved in INPP5E activation ENSG00000087586 ENSG00000148384 PMC8160090__F1 JAK-STAT in Early Hematopoiesis and Leukemia ENSG00000107562 ENSG00000105397 ENSG00000115415 ENSG00000137392 ENSG00000105639 ENSG00000168610 PMC9467317__F1 TNFR1 signal transduction pathway ENSG00000102871 ENSG00000166278 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 PMC8979819__F8 Schematic summarizing the effects of Gab2 on RTK expression and signaling in Flt3-ITD positive AML ENSG00000167601 ENSG00000033327 ENSG00000168546 PMC1361319__F1 Scheme of branch pathways of phenylpropanoid metabolism in plants leading to the synthesis of anthocyanins, flavonols, PAs, and lignin ENSG00000084774 PMC4618268__F1 Everolimus Combined With Gefitinib in Patients with Metastatic Castration-Resistant Prostate Cancer: Phase I/II Results and Signaling Pathway Implications ENSG00000146648 ENSG00000140443 PMC11653102__F8 AD-like neuropsychiatric dysfunction in a mice model induced by the combination of high-fat diet and intraperitoneal injection of streptozotocin ENSG00000169047 PMC8226009__F4 N6-Methyladenosine RNA Methylation Regulator-Related Alternative Splicing (AS) Gene Signature Predicts Non–Small Cell Lung Cancer Prognosis ENSG00000114670 ENSG00000105722 ENSG00000087095 ENSG00000142192 ENSG00000095321 ENSG00000010810 ENSG00000000971 ENSG00000150787 ENSG00000123562 ENSG00000166169 ENSG00000140464 ENSG00000117305 PMC2215060__F1A WE GATHER TOGETHER: INSULATORS AND GENOME ORGANIZATION ENSG00000102974 PMC8084285__F2 Promising role of defensins peptides as therapeutics to combat against viral infection ENSG00000169291 ENSG00000130234 ENSG00000148798 PMC5278199__F1 Human EGF signaling pathway (reprinted from Biocarta ) ENSG00000169291 ENSG00000167941 ENSG00000138798 ENSG00000168610 PMC5993136__F1 Regulation of lipid metabolism in cancer cells ENSG00000131473 ENSG00000135218 ENSG00000130164 ENSG00000042832 ENSG00000198793 ENSG00000113161 ENSG00000169710 ENSG00000285482 ENSG00000075239 ENSG00000062282 PMC3786223__F2 The potential role of miRNAs in the attenuated myogenic process in the elderly ENSG00000099804 PMC11885449__F10 Mito-nuclear carbon metabolism in Toxoplasma ENSG00000122966 ENSG00000134982 ENSG00000172005 PMC4177046__F1 Aberrant Regulation and Function of MicroRNAs in Cancer ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC4631599__F9 Intracellular Networks of the PI3K/AKT and MAPK Pathways for Regulating Toxoplasma gondii-Induced IL-23 and IL-12 Production in Human THP-1 Cells ENSG00000124102 ENSG00000136869 PMC4057758__F6 Graphical representation of two of the top score networks identified by Ingenuity Pathway Analysis (IPA) ENSG00000228716 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000101945 ENSG00000132646 ENSG00000169375 PMC3696504__F1 Relationship between metabolism and the autophagy machinery during the innate immune response ENSG00000152348 ENSG00000150782 ENSG00000198382 ENSG00000111537 ENSG00000144848 ENSG00000113520 ENSG00000145782 ENSG00000057663 PMC2196458__F7 Fas-signaling pathways in relation to the cytoskeletal networks, the Golgi-sorting compartment, and the surface membrane ENSG00000138798 ENSG00000145321 ENSG00000168040 ENSG00000146648 ENSG00000026103 PMC4262781__F1 Aberrant miRNA expression in liver cancer promotes cell-cycle progression ENSG00000135446 ENSG00000132646 ENSG00000136997 ENSG00000123374 ENSG00000105810 ENSG00000101224 ENSG00000139687 PMC12072370__F4 Knockout of StNADC has devastating effects on NAD synthesis and activates plant senescence and tuberization pathways ENSG00000154269 ENSG00000105835 ENSG00000073578 ENSG00000136159 ENSG00000117118 ENSG00000008130 ENSG00000163382 ENSG00000283100 PMC116060__F6 Proposed signal transduction pathways involved in PKC-mediated SRE activation PMC4262781__F2 Aberrant miRNA expression in liver cancer affects the functionality of apoptosis pathways ENSG00000132906 ENSG00000171791 ENSG00000164305 ENSG00000149311 ENSG00000175054 ENSG00000113328 ENSG00000135446 ENSG00000132646 ENSG00000136997 ENSG00000123374 ENSG00000105810 ENSG00000120868 ENSG00000064012 ENSG00000026103 PMC8222170__F7 KEGG pathology and disease analysis ENSG00000105664 ENSG00000142192 ENSG00000002330 PMC3178285__F5 Proposed signaling of TNFA− and leptin-induced EL upregulation in primary placental ECs ENSG00000101670 ENSG00000110514 ENSG00000102871 ENSG00000127191 PMC11848126__F2 MTOR signalling pathway, highlighting mTORC1 and interactions that regulate canonical initiation ENSG00000140992 ENSG00000177169 ENSG00000155506 ENSG00000128272 ENSG00000136937 ENSG00000198793 ENSG00000284161 ENSG00000167658 ENSG00000179632 ENSG00000089289 PMC6938856__F10 Silencing of Long Non-coding RNA RP1-93H18.6 Acts as a Tumor Suppressor in Cervical Cancer through the Blockade of the PI3K/Akt Axis ENSG00000198793 ENSG00000168036 PMC11848126__F4 CK2 signalling pathway, highlighting interactions that regulate canonical initiation ENSG00000140992 ENSG00000155506 ENSG00000104131 ENSG00000128272 ENSG00000105329 ENSG00000132326 ENSG00000130811 ENSG00000175390 ENSG00000161960 PMC3030971__F1 Key proteins and pathways in the replication stress response network ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000276618 ENSG00000197299 ENSG00000051180 ENSG00000128908 PMC10728939__F3 Signaling pathways regulated by BAMBI ENSG00000281324 ENSG00000162337 ENSG00000095739 ENSG00000170458 ENSG00000134982 ENSG00000172936 ENSG00000136869 ENSG00000162692 ENSG00000175104 ENSG00000196628 PMC6523967__F1 Cyclin D1–CDK4/6–Rb pathway in breast cancer ENSG00000135446 ENSG00000198793 ENSG00000168036 ENSG00000123374 ENSG00000105810 PMC6598324__F7 The potential mechanism of FOXP3-mediated regulation of cancer cell stemness ENSG00000148400 ENSG00000049768 ENSG00000114315 PMC10886574__F3 Sirtuins Affect Cancer Stem Cells via Epigenetic Regulation of Autophagy ENSG00000178860 ENSG00000162711 ENSG00000187531 ENSG00000138336 ENSG00000168036 ENSG00000077463 ENSG00000142082 ENSG00000089163 ENSG00000121966 ENSG00000283100 PMC5851329__F4 Summary of Potential Eph/Ephrin Tumor Promoting Pathways ENSG00000010810 ENSG00000163914 ENSG00000168036 ENSG00000168610 PMC10886574__F2 The SIRT1–c-Myc axis in the control of stem cells ENSG00000124422 ENSG00000164362 ENSG00000096717 PMC2682019__F9 A link between glucose and insulin signaling in Beta-cells ENSG00000150907 ENSG00000198793 PMC8267928__F5 Immunity Depletion, Telomere Imbalance, and Cancer-Associated Metabolism Pathway Aberrations in Intestinal Mucosa upon Short-Term Caloric Restriction ENSG00000051523 ENSG00000159224 ENSG00000135218 ENSG00000058085 ENSG00000183486 ENSG00000145113 ENSG00000197273 ENSG00000109854 ENSG00000145431 ENSG00000132530 ENSG00000065833 ENSG00000107263 ENSG00000079246 ENSG00000011422 ENSG00000104894 ENSG00000152217 ENSG00000269404 ENSG00000157111 ENSG00000169903 ENSG00000100558 ENSG00000175155 ENSG00000114771 ENSG00000085552 ENSG00000140263 ENSG00000124701 ENSG00000182156 ENSG00000008394 ENSG00000160182 ENSG00000103888 ENSG00000179820 ENSG00000124205 ENSG00000169752 ENSG00000007171 ENSG00000135587 ENSG00000063176 ENSG00000115415 ENSG00000196371 ENSG00000171848 ENSG00000085871 ENSG00000285379 ENSG00000143954 PMC8267928__F6 Immunity Depletion, Telomere Imbalance, and Cancer-Associated Metabolism Pathway Aberrations in Intestinal Mucosa upon Short-Term Caloric Restriction ENSG00000112799 ENSG00000183486 ENSG00000142082 ENSG00000161955 ENSG00000135899 ENSG00000168062 ENSG00000065833 ENSG00000131238 ENSG00000088888 ENSG00000011422 ENSG00000269404 ENSG00000083720 ENSG00000178828 ENSG00000165471 ENSG00000124256 ENSG00000140263 ENSG00000163874 ENSG00000196954 ENSG00000169752 ENSG00000007171 ENSG00000184979 ENSG00000136603 ENSG00000169245 ENSG00000172497 ENSG00000106853 ENSG00000116761 ENSG00000090659 PMC8267928__F7 Immunity Depletion, Telomere Imbalance, and Cancer-Associated Metabolism Pathway Aberrations in Intestinal Mucosa upon Short-Term Caloric Restriction ENSG00000174156 ENSG00000170899 ENSG00000008394 ENSG00000069956 ENSG00000142082 ENSG00000176153 ENSG00000007171 ENSG00000109819 ENSG00000101945 ENSG00000079246 ENSG00000101773 ENSG00000181019 ENSG00000165392 ENSG00000171848 ENSG00000085871 ENSG00000124253 ENSG00000168765 PMC7538784__F1 Current mechanisms proposed for metformin in pathological pain ENSG00000111537 ENSG00000110931 ENSG00000151151 PMC4854363__F3 Negative regulatory NLR functions during viral infection ENSG00000183735 ENSG00000088888 ENSG00000160703 ENSG00000142405 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC8267928__F3 Immunity Depletion, Telomere Imbalance, and Cancer-Associated Metabolism Pathway Aberrations in Intestinal Mucosa upon Short-Term Caloric Restriction ENSG00000114771 ENSG00000157933 ENSG00000135218 ENSG00000140263 ENSG00000183486 ENSG00000166278 ENSG00000184979 ENSG00000135899 ENSG00000182511 ENSG00000131238 ENSG00000088888 ENSG00000011422 ENSG00000159263 ENSG00000285379 ENSG00000116761 PMC7016866__F8 Model for the activation of Notch2 signaling in renal tubular epithelial cells under high glucose conditions and the possible actions of LE or LE/GC-KO in suppressing the Notch2 signaling cascade ENSG00000283780 PMC8267878__F5 Current Understanding of IL-37 in Human Health and Disease ENSG00000115009 PMC12078438__F5 NI-ADSCs activating the Notch pathway to promote nerve regeneration by inducing and maintaining the reparative phenotype of Schwann cells ENSG00000148400 ENSG00000131095 ENSG00000114315 PMC6638267__F8 Working model for the role of peroxisomes in fungal infection ENSG00000124587 ENSG00000288217 ENSG00000162928 PMC10875036__F5 IAV NS1 and SARS-CoV-2 Nsp1 antagonism of innate immune responses ENSG00000213928 ENSG00000088888 ENSG00000187608 ENSG00000105397 ENSG00000144895 ENSG00000115415 ENSG00000172936 ENSG00000121060 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC3751673__F3 Ingenuity pathway analysis of the top-ranked network ENSG00000102962 ENSG00000123496 ENSG00000165030 ENSG00000158477 ENSG00000158485 ENSG00000274736 ENSG00000292363 ENSG00000163606 ENSG00000056736 PMC3508196__F1 TARGETING ONCOGENIC BRAF IN HUMAN CANCER ENSG00000157404 ENSG00000198793 ENSG00000136997 ENSG00000146648 ENSG00000196712 PMC6721815__F2 MAPK signalling in the context of wild type BRAF and mutant BRAFV600E ENSG00000157764 ENSG00000048028 ENSG00000196712 PMC6721815__F3 Adaptive response-mediated resistance to BRAF inhibitors in melanoma ENSG00000157764 ENSG00000065361 ENSG00000112561 ENSG00000048028 ENSG00000100146 ENSG00000146648 PMC4931622__F1 The Wnt/Beta-catenin signaling pathway in renal cell carcinoma (RCC) ENSG00000134086 ENSG00000156076 ENSG00000134982 ENSG00000141753 ENSG00000168036 PMC7730698__F2 Role of CK1D/E in the Wnt signaling pathways ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000136997 ENSG00000185483 ENSG00000168036 ENSG00000049768 PMC10527795__F1 Wnt signaling pathway ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000070831 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC6160310__F1 Hepatitis E Virus life cycle ENSG00000213928 ENSG00000111537 ENSG00000187608 ENSG00000115415 ENSG00000074319 ENSG00000027697 ENSG00000156976 ENSG00000291420 ENSG00000276561 ENSG00000107581 PMC7892472__F1 Key aspects of BAFF-R, TACI, and BCMA signaling within the context of CVID ENSG00000104856 ENSG00000173039 ENSG00000131323 ENSG00000171791 ENSG00000127191 PMC3873642__F1 A proposed model of the DNA-damage response pathway ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000112130 PMC11204528__F8 Dicerandrol C Suppresses Proliferation and Induces Apoptosis of HepG2 and Hela Cancer Cells by Inhibiting Wnt/Beta-Catenin Signaling Pathway ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC7462918__F3 Membrane trafficking of SGLT1/Sglt1 ENSG00000105329 ENSG00000118515 ENSG00000102104 PMC4384750__F9 Model of SOX2 feedback signaling pathway ENSG00000281518 ENSG00000146648 ENSG00000104081 PMC9374328__F1 c-Met: A Promising Therapeutic Target in Bladder Cancer ENSG00000019991 ENSG00000291971 ENSG00000166278 PMC12206656__F4 Copper is closely associated with various forms of PCD ENSG00000278718 ENSG00000162711 ENSG00000124256 ENSG00000182511 ENSG00000167468 ENSG00000198793 ENSG00000158828 ENSG00000285379 PMC8072220__F8 Complex of distal appendage–associated kinases linked to human disease regulates ciliary trafficking and stability ENSG00000023902 ENSG00000110274 ENSG00000101266 ENSG00000128602 PMC3713213__F7 Signaling pathways showing mechanisms involved in the protective effects of cardiac-specific CYP2J2 transgenic mice subjected to diabetic stress ENSG00000175054 ENSG00000169047 ENSG00000134716 PMC8066826__F2 Adiponectin and its receptors and schematic representation of adiponectin-induced signaling pathway ENSG00000157500 ENSG00000198793 ENSG00000159346 ENSG00000285070 PMC9104939__F6 Recent Advancements in Antifibrotic Therapies for Regression of Liver Fibrosis ENSG00000117020 ENSG00000239732 ENSG00000136869 ENSG00000171791 ENSG00000140443 PMC6952948__F5 The role of mTOR in glutamine metabolism and hexosamine biosynthesis ENSG00000136997 ENSG00000115419 PMC6952948__F6 The role of mTOR in the pentose phosphate pathway and nucleotide synthesis ENSG00000178035 ENSG00000065911 ENSG00000136997 ENSG00000153574 ENSG00000084774 ENSG00000254550 PMC7961658__F7 Possible mechanism of action of glycyrrhizin (GL) in colon cancer ENSG00000125398 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC9343382__F1 Reduced nicotinamide adenine dinucleotide phosphate in redox balance and diseases: a friend or foe? ENSG00000105835 ENSG00000123572 ENSG00000278488 PMC4386408__F5 The mechanism of the switch off in Shh canonical signaling during spinal cord development ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC4994041__F7 The Hippo-Salvador signaling pathway regulates renal tubulointerstitial fibrosis ENSG00000168036 PMC4130654__F1 PI3K-PTEN-mTOR pathway ENSG00000005882 ENSG00000163914 ENSG00000118515 ENSG00000155792 PMC7566413__F2 Regulatory Function of CCR9+ Dendritic Cells in Inflammation and Autoimmunity ENSG00000131142 ENSG00000049768 PMC10874556__F1 Mechanical cue-dependent scarring ENSG00000169554 ENSG00000137033 ENSG00000168610 ENSG00000124782 PMC3095361__F9 ROS, elicitor and hormone regulation of O3-induced CRKs ENSG00000256453 PMC5581728__F2 Molecular actions of HDIs in sarcoma ENSG00000168040 PMC3116122__F1 PI3K pathway activates different processes that regulate proliferation, apoptosis and migration ENSG00000002330 ENSG00000198793 ENSG00000163914 ENSG00000146648 PMC3372068__F1 Coagulation and complement cascades ENSG00000166278 ENSG00000062485 PMC7013859__F2 LPS recognition by toll-like receptor 4 (TLR4) ENSG00000170458 ENSG00000172936 ENSG00000136869 PMC7216071__F8 Activation mechanism of miR-223 negative regulation of the TLR4/MyD88-NFKB signaling pathway ENSG00000162711 ENSG00000125538 ENSG00000172936 PMC517537__F7 Signaling kinases involved in regulation of TNFA, IL-10, and IL-6 in Kupffer cells ENSG00000226275 ENSG00000291971 PMC3428770__F2 Signalling events activating PKB/Akt and cellular functions regulated by PKB/Akt ENSG00000183735 ENSG00000033327 ENSG00000002330 ENSG00000105401 ENSG00000060237 ENSG00000136111 ENSG00000197386 PMC6423427__F1 Overview of UPR signaling pathway ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8036623__F2 Proteolysis on the VEGF pathway ENSG00000087245 ENSG00000115415 ENSG00000100985 ENSG00000122194 PMC3587611__F8 Dullard/Ctdnep1 Modulates WNT Signalling Activity for the Formation of Primordial Germ Cells in the Mouse Embryo ENSG00000162337 ENSG00000096088 ENSG00000175826 ENSG00000168036 ENSG00000277641 PMC9557158__F9 MiR-21 and let-7 cooperation in the regulation of lung cancer ENSG00000131914 ENSG00000181690 ENSG00000187772 PMC3759196__F9 Aberrant Signaling Pathways in Glioma ENSG00000170365 ENSG00000168283 ENSG00000106571 ENSG00000118503 ENSG00000148400 ENSG00000074181 ENSG00000205927 ENSG00000164690 ENSG00000128602 ENSG00000168610 ENSG00000196367 PMC4177022__F6 Proposed mechanism of testicular apoptotic response to x-ray exposure ENSG00000023445 ENSG00000132906 ENSG00000169857 ENSG00000120868 ENSG00000064012 ENSG00000026103 PMC3196283__F1 BER pathways BER is initiated by a damage specific DNA glycosylase and APE1 that excise the damaged base and incise the arising abasic site, respectively generating a DNA single strand break with a 5'-sugar phosphate ENSG00000132646 PMC3759196__F6 RTK/PI3K/Akt signaling PMC3759196__F7 P53 pathway and retinoblastoma (RB) tumor suppressor protein signaling are shown ENSG00000149311 ENSG00000135446 ENSG00000139687 ENSG00000198625 PMC3650616__F9 MEK inhibition increases lapatinib sensitivity via modulation of FOXM1 ENSG00000198793 ENSG00000146648 PMC12072112__F5 Insulin resistance, neuroinflammation, and tau pathology in Alzheimer’s disease ENSG00000198793 ENSG00000136869 ENSG00000119912 PMC12072112__F1 Insulin signaling pathway regulating glucose uptake and storage ENSG00000169047 ENSG00000198793 PMC12072112__F2 Interaction between insulin signaling, inflammation, and oxidative stress in cellular metabolism ENSG00000042832 ENSG00000169047 ENSG00000198793 PMC10757641__F1 G protein-coupled receptors and obesity ENSG00000159224 ENSG00000288269 ENSG00000198576 ENSG00000115138 ENSG00000166603 ENSG00000121853 ENSG00000131096 ENSG00000010310 PMC11983301__F2 Podocytes, renal tubular epithelial cells, and glomerular mesangial cells in DKD ENSG00000124422 ENSG00000285109 ENSG00000134982 ENSG00000204977 ENSG00000158828 ENSG00000137699 ENSG00000169710 ENSG00000155313 ENSG00000092871 ENSG00000134086 ENSG00000158022 ENSG00000198742 ENSG00000083799 ENSG00000175104 ENSG00000096717 ENSG00000109670 PMC12228841__F5 TLR2 and TLR4 signaling pathways and their interplay ENSG00000174125 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC4779598__F5 A proposed model illustrating how SOX4 interacts with PI3K-AKT, Wnt-Beta-catenin, and AR signaling pathways, and how the PI3K-AKT-mTOR pathway regulates the expression of SOX4 in prostate cancer progression ENSG00000138798 ENSG00000124766 ENSG00000168036 ENSG00000146648 PMC4264417__F2 Notch receptor and pathway ENSG00000283780 ENSG00000148400 ENSG00000074181 ENSG00000138798 PMC4264417__F3 Notch–EGFR crosstalk in TNBC ENSG00000148400 ENSG00000138798 ENSG00000146648 PMC4264417__F4 Notch–HER2 crosstalk in HER2+ BC (A) ENSG00000113905 ENSG00000138798 PMC8077955__F2 Galectin-3: a key player in microglia-mediated neuroinflammation and Alzheimer's disease ENSG00000153208 ENSG00000136869 PMC4264417__F1 HER receptor and pathway: (A) there are four members of the HER family of RTKs: EGFR/HER1, HER2, 3, and 4 ENSG00000005882 ENSG00000138798 ENSG00000155792 ENSG00000074266 ENSG00000146648 PMC5930388__F5 PI3K/AKT/mTOR pathway PMC2330246__F1 Overview of NAD biosynthesis and salvage pathways and a link with other metabolic pathways via ADP-ribose ENSG00000197713 PMC4856023__F3 The blockade of immune checkpoints in cancer immunotherapy ENSG00000163599 PMC4183535__F4 Maternal Obesity and Tobacco Use Modify the Impact of Genetic Variants on the Occurrence of Conotruncal Heart Defects ENSG00000174156 ENSG00000142182 ENSG00000158467 ENSG00000170899 ENSG00000136371 ENSG00000170430 ENSG00000185339 ENSG00000035928 ENSG00000132840 PMC11049885__F2 Network comprised of the IRs affecting ecdysone synthesis ENSG00000137713 ENSG00000152240 ENSG00000141551 ENSG00000169856 ENSG00000172269 ENSG00000197563 ENSG00000176101 ENSG00000166484 ENSG00000166886 ENSG00000072210 ENSG00000116133 ENSG00000109929 ENSG00000168546 ENSG00000197386 ENSG00000057252 ENSG00000108515 ENSG00000144744 ENSG00000151461 ENSG00000163902 ENSG00000085662 ENSG00000135900 ENSG00000197712 ENSG00000186298 ENSG00000006534 ENSG00000135916 ENSG00000133858 ENSG00000267673 ENSG00000142892 ENSG00000101004 ENSG00000148019 ENSG00000001630 ENSG00000135446 ENSG00000172339 ENSG00000284944 ENSG00000292254 ENSG00000198911 PMC11049885__F3 Network comprised of the IRs that compete with ecdysone synthesis ENSG00000137713 ENSG00000152240 ENSG00000141551 ENSG00000169856 ENSG00000172269 ENSG00000197563 ENSG00000176101 ENSG00000166484 ENSG00000166886 ENSG00000181019 ENSG00000072210 ENSG00000116133 ENSG00000057252 ENSG00000108515 ENSG00000100344 ENSG00000144744 ENSG00000151461 ENSG00000163902 ENSG00000085662 ENSG00000135900 ENSG00000197712 ENSG00000186298 ENSG00000006534 ENSG00000135916 ENSG00000133858 ENSG00000267673 ENSG00000101004 ENSG00000148019 ENSG00000001630 ENSG00000135446 ENSG00000204673 ENSG00000120942 ENSG00000172339 ENSG00000147874 ENSG00000284944 ENSG00000198911 PMC9446423__F2 Endocrine therapy resistance: what we know and future directions ENSG00000185591 PMC5222515__F5 Methodology for Cancer Therapeutics by Systems Pharmacology-Based Analysis: A Case Study on Breast Cancer-Related Traditional Chinese Medicines ENSG00000133019 ENSG00000180720 ENSG00000082175 ENSG00000128052 ENSG00000137193 ENSG00000146648 ENSG00000007171 PMC2796982__F3 Regulation of convergence and extension movements during vertebrate gastrulation by the Wnt/PCP pathway ENSG00000070831 ENSG00000100592 ENSG00000134982 ENSG00000163914 ENSG00000104290 ENSG00000168036 ENSG00000125084 PMC11049885__F6 Key IRs significantly affecting ecdysone synthesis ENSG00000267673 ENSG00000109929 ENSG00000198911 PMC7404026__F1 Canonical and non-canonical Nuclear factor kappa B (NFKB) signaling pathways ENSG00000104856 ENSG00000226275 ENSG00000291603 ENSG00000102871 ENSG00000186716 ENSG00000173039 ENSG00000172936 ENSG00000162924 ENSG00000175104 ENSG00000127191 ENSG00000010671 PMC6005692__F11 HIV-1 gp120 up-regulates BDNF expression in BV2 cells via Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167074 PMC8338882__F2 HPV immune modulation of the tumor microenvironment ENSG00000049768 PMC7290828__F1 Mitochondrial Protein Quality Control System (MPQC) ENSG00000166855 ENSG00000162600 ENSG00000158828 ENSG00000125656 ENSG00000135517 ENSG00000115317 PMC3732602__F1 TGFB signaling ENSG00000163914 PMC8621451__F5A Positive Salt Tolerance Modulation via Vermicompost Regulation of SOS1 Gene Expression and Antioxidant Homeostasis in Vicia faba Plant ENSG00000115904 ENSG00000100485 PMC3732602__F5 TGFB processing and uPA-uPAR-dependent activation ENSG00000140564 ENSG00000122194 PMC10140933__F12 Pathways of protein synthesis and transport activated by CsRALF34 overexpression (based on the KEGG signal pathway database) ENSG00000089154 ENSG00000292366 PMC3240715__F3 Molecular mechanisms of FGFR3 signaling in cartilage ENSG00000115415 ENSG00000115904 ENSG00000173786 ENSG00000128342 ENSG00000163501 ENSG00000168610 PMC8100490__F7 Zearalenone exposure affects the Wnt/Beta-catenin signaling pathway and related genes of porcine endometrial epithelial cells in vitro ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000162607 ENSG00000168036 PMC4409267__F1 Characterization of Phospholipids in Insulin Secretory Granules and Mitochondria in Pancreatic Beta Cells and Their Changes with Glucose Stimulation ENSG00000173599 ENSG00000120437 ENSG00000075239 ENSG00000026103 PMC2999931__F2 Postsqualene cholesterol synthetic pathway ENSG00000132196 ENSG00000116133 ENSG00000143815 ENSG00000172893 ENSG00000109929 PMC7248321__F5 Multiple signaling networks are regulated by hsa-miR-205-5p based on ingenuity pathway analysis (IPA) ENSG00000197892 ENSG00000139567 ENSG00000132824 ENSG00000138443 ENSG00000100227 ENSG00000007047 ENSG00000057663 ENSG00000163171 ENSG00000049130 ENSG00000101871 ENSG00000148773 ENSG00000165458 ENSG00000136997 ENSG00000119408 ENSG00000025293 ENSG00000104081 ENSG00000214253 ENSG00000136068 ENSG00000109321 ENSG00000173039 ENSG00000073712 ENSG00000163435 ENSG00000154305 ENSG00000164050 ENSG00000134278 ENSG00000143776 ENSG00000109805 ENSG00000131351 ENSG00000177096 ENSG00000184371 ENSG00000106554 ENSG00000132341 PMC7149230__F5 Synchronization of central carbon enzyme and metabolite abundance with cell cycle phases ENSG00000122966 ENSG00000100412 ENSG00000172005 PMC6760157__F6 Cystathionine Beta-synthase (CBS) deficiency suppresses erythropoiesis by disrupting expression of heme biosynthetic enzymes and transporter ENSG00000066926 ENSG00000158578 ENSG00000187266 PMC3784205__F6 Skeletal muscle carnitine loading increases energy expenditure, modulates fuel metabolism gene networks and prevents body fat accumulation in humans ENSG00000157184 ENSG00000005882 ENSG00000177666 PMC2729268__F2 Map of protein interactivity (binding, regulation, modification) between genes revealed to be significantly associated with bladder cancer in urothelial cell samples ENSG00000164161 ENSG00000078369 ENSG00000157193 ENSG00000159461 ENSG00000072274 ENSG00000162772 PMC5661256__F7 Schematic diagram of a signalling pathway related to anti‐apoptotic or anti‐inflammatory effects of polydatin on LTA‐induced injury ENSG00000132906 ENSG00000226275 ENSG00000164305 PMC4625495__F1 Epigallocatechin-3-gallate treatment to promote neuroprotection and functional recovery after nervous system injury PMC4389564__F1 CD44 acts as a co-receptor for several cell surface receptors including RTKs, G-protein coupled receptors, and LRP6 ENSG00000281324 ENSG00000163739 ENSG00000026508 ENSG00000168036 ENSG00000121966 PMC8942208__F3 Differentially expressed components of four of interesting pathways involved in immune response and drug metabolism in F. gigantica-infected hLNs and pBLs ENSG00000110944 ENSG00000174156 ENSG00000183625 ENSG00000163083 ENSG00000175592 ENSG00000189430 ENSG00000124875 ENSG00000150782 ENSG00000163734 ENSG00000113520 ENSG00000128342 ENSG00000171560 ENSG00000170899 ENSG00000115008 ENSG00000172955 ENSG00000073756 ENSG00000006534 ENSG00000169245 ENSG00000112116 ENSG00000278624 ENSG00000102970 ENSG00000178732 ENSG00000188130 ENSG00000100985 ENSG00000005381 ENSG00000113302 PMC4255043__F1 Induction of nuclear factor-activated T cells c1 (NFATc1) in osteoclasts ENSG00000170909 ENSG00000204103 ENSG00000101307 ENSG00000140968 ENSG00000175104 ENSG00000131196 PMC10931359__F3 S1PR signaling pathways in liver regeneration and HCC progression ENSG00000163914 ENSG00000170989 ENSG00000213694 ENSG00000267534 PMC7486245__F1 Components of the TgfB signaling pathway that have been implicated in cardiomyocyte proliferation ENSG00000170365 ENSG00000137834 PMC7669638__F2 Molecular Regulation of Cdk5 activity ENSG00000010810 PMC4104512__F4 Functional zonation of the rat adrenal cortex: the development and maintenance ENSG00000179142 PMC6902440__F4 Interactions of TGFB pathways, WNT, Smad and the Hippo pathway in fibrosis ENSG00000150457 ENSG00000131023 PMC6902440__F2 TGFB1 effects on the balance between the canonical WNT/Beta-catenin pathway and PPARG ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6910186__F8 Roles of miR-21 and the PDCD4/c-Jun signalling pathway in renal cell carcinoma ENSG00000087245 ENSG00000100985 ENSG00000112715 PMC3303581__F1 Myostatin signals through the ActRIIB-ALK4/5 heterodimer activate Smad2/3 with blocking of MyoD transactivation in an autoregulatory feedback loop ENSG00000198793 PMC5363987__F8 CUZD1 is a critical mediator of the JAK/STAT5 signaling pathway that controls mammary gland development during pregnancy ENSG00000124882 ENSG00000138161 ENSG00000178568 ENSG00000113494 PMC6487484__F1 Mechanisms Linking Mechanotransduction and Cell Metabolism ENSG00000168036 PMC10686715__F2 Exosomes from different MSCs mediate PCD in myocardial cells after myocardial infarction ENSG00000178860 ENSG00000162711 ENSG00000198793 ENSG00000131323 ENSG00000115107 ENSG00000057663 PMC6487484__F2 Mechanisms Linking Mechanotransduction and Cell Metabolism ENSG00000168036 PMC4367964__F5 Natural Selection in a Bangladeshi Population from the Cholera-Endemic Ganges River Delta ENSG00000144028 ENSG00000162711 ENSG00000169896 ENSG00000196954 ENSG00000127666 ENSG00000175634 ENSG00000150782 ENSG00000124216 ENSG00000103490 ENSG00000149968 ENSG00000125538 ENSG00000167986 ENSG00000144021 ENSG00000189403 ENSG00000136869 PMC10686715__F4 Angiogenic effect of exosomes released by different MSCs after MI ENSG00000178860 ENSG00000019991 ENSG00000143590 ENSG00000150687 PMC4229635__F6 Shed Sdc-1 induces the activation of EGFR and downstream signalling pathways via sHB-EGF ENSG00000137673 ENSG00000113070 ENSG00000100985 ENSG00000146648 PMC10686715__F5 Exosomes secreted by different sources of MSCs regulate the inflammatory microenvironment after myocardial infarction ENSG00000178860 ENSG00000182511 ENSG00000153094 PMC8599300__F4 Mechanistic Target of Rapamycin Complex 2 Regulation of the Primary Human Trophoblast Cell Transcriptome ENSG00000162889 ENSG00000170458 ENSG00000175899 ENSG00000127191 ENSG00000168610 ENSG00000132693 PMC5786332__F6 HIV replication in monocyte derived macrophages (MDM) by steroid hormones ENSG00000171855 ENSG00000169248 ENSG00000188379 ENSG00000169245 ENSG00000104365 ENSG00000125538 ENSG00000138755 ENSG00000164136 ENSG00000233816 ENSG00000113302 ENSG00000142166 PMC4196580__F6 Toll-like receptor signaling pathway showing the annotated and non-annotated proteins ENSG00000239732 ENSG00000144410 ENSG00000170458 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000164342 ENSG00000143387 PMC4196580__F7 B cell receptor signaling pathway showing the annotated and non-annotated proteins ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000145321 PMC4196580__F8 T cell receptor signaling pathway showing the annotated and non-annotated proteins ENSG00000110395 ENSG00000213658 ENSG00000117091 ENSG00000010810 ENSG00000135446 ENSG00000113263 PMC4196580__F9 Chemokine signaling pathway showing the annotated and non-annotated proteins ENSG00000169291 ENSG00000173156 ENSG00000162924 ENSG00000113263 PMC8755678__F3 Endothelium function by fatty acids ENSG00000128917 ENSG00000148400 ENSG00000150907 ENSG00000136997 ENSG00000127528 ENSG00000112715 PMC3489747__F2 TLR3/TICAM-1 signaling in tumor cell RIP3-dependent necroptosis ENSG00000183735 ENSG00000105664 ENSG00000168040 PMC7473858__F8 Pathway modeling for genome signaling and metabolic reconstruction revealed the pathological mechanism of oral cancer using KEGG and Wiki pathway databases PMC7028849__F8 Schematic illustration on possible roles of aminooxyacetic acid (AOAA) on macrophage metabolism and polarization ENSG00000135218 PMC7281956__F10 The ROS/PARP/TRPM2 signaling pathway that mediates SiNPs-induced pulmonary inflammation in mice ENSG00000163739 ENSG00000284099 ENSG00000169429 ENSG00000227345 PMC9621617__F4 Alterations in bone fracture healing associated with TNFRSF signaling pathways ENSG00000178860 ENSG00000168040 ENSG00000131196 PMC2799380__F6 Connective tissue associated signalling network common to various cardiac hypertrophy animal models and human cardiac disease ENSG00000163399 ENSG00000139514 ENSG00000142192 ENSG00000119138 ENSG00000145623 ENSG00000291748 ENSG00000137573 ENSG00000108821 ENSG00000146648 ENSG00000115461 ENSG00000187955 ENSG00000062485 ENSG00000135919 PMC11053956__F6 JAK/STAT signaling pathway mapper ENSG00000188486 ENSG00000162711 ENSG00000124256 ENSG00000099985 ENSG00000137033 ENSG00000102871 ENSG00000168040 ENSG00000182511 ENSG00000136869 ENSG00000083799 ENSG00000168404 ENSG00000143258 ENSG00000164342 PMC7428229__F7 DEGs mapped to the cysteine and methionine metabolism pathway in shoots ENSG00000149089 ENSG00000182551 ENSG00000037757 ENSG00000102172 PMC8176883__F3 Proteomics-Based Insights Into the SARS-CoV-2–Mediated COVID-19 Pandemic: A Review of the First Year of Research ENSG00000204120 ENSG00000100345 ENSG00000137996 PMC7300268__F4 YAP/TAZ regulation by lipid metabolism and YAP/TAZ-targets for Lipid metabolism ENSG00000113161 ENSG00000168036 ENSG00000198670 ENSG00000026103 PMC6161735__F1 Nrf2/Keap1 signaling pathway in homeostatisis and stress ENSG00000178573 ENSG00000079999 PMC3251842__F2 TGFB response pathway PMC5817727__F4 Regulation of PTEN, a major regulator of the PI3K/AKT signalling pathway PMC9412181__F1 Overexpression of enzymes in glycolysis and energy metabolic pathways to enhance coenzyme Q10 production in Rhodobacter sphaeroides VK-2-3 ENSG00000131473 ENSG00000110921 ENSG00000073578 ENSG00000159322 ENSG00000105953 PMC5831902__F3 The calcineurin/NFAT signaling pathway and the miRNAs involved in feedback loops to modulate the pathway activities ENSG00000157540 ENSG00000167323 ENSG00000293604 ENSG00000103942 PMC6862668__F1 Signaling pathways and therapeutic targets ENSG00000112715 ENSG00000163217 PMC5348387__F6 Oncolytic vaccinia virus combined with radiotherapy induces apoptotic cell death in sarcoma cells by down-regulating the inhibitors of apoptosis ENSG00000002330 PMC5734142__F1 Reduced Retinoblastoma Protein Expression Is Associated with Decreased Patient Survival in Medullary Thyroid Cancer ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC4009444__F2 Intracellular signaling pathways for hepcidin expression ENSG00000170365 ENSG00000010704 PMC4397969__F1 (De-) Oiling Inflammasomes ENSG00000162711 ENSG00000141480 ENSG00000125538 ENSG00000172936 PMC8226720__F1 An Overview on Diffuse Large B-Cell Lymphoma Models: Towards a Functional Genomics Approach ENSG00000139193 ENSG00000118503 ENSG00000140968 ENSG00000186716 ENSG00000118515 ENSG00000273936 ENSG00000135144 PMC8848207__F1 Role and mechanism of action of LAPTM4B in EGFR-mediated autophagy ENSG00000198382 ENSG00000144895 ENSG00000168610 ENSG00000146648 ENSG00000057663 PMC8848207__F2 Role and mechanism of action of LAPTM4B in EGFR-mediated autophagy ENSG00000198793 ENSG00000144848 ENSG00000104341 ENSG00000168610 ENSG00000146648 PMC9177660__F2 NcRNAs implicated in regulation of ferroptosis ENSG00000151012 ENSG00000167468 ENSG00000187855 PMC8879474__F5 Tissue Transglutaminase but Not Microbial Transglutaminase Is Inhibited by Exogenous Oxidative Substances in Celiac Disease ENSG00000111537 ENSG00000134982 PMC9685814__F2 From kitchen to clinic: Pharmacotherapeutic potential of common spices in Indian cooking in age-related neurological disorders ENSG00000114200 ENSG00000087085 PMC6597757__F2 Illustration depicting primary signalling mechanisms of different neuronal and astrocytic proteins encoded by genes implicated in ID/ASDs ENSG00000198793 ENSG00000292254 PMC8558397__F1 Gut Microbiota-Derived Metabolites in Colorectal Cancer: The Bad and the Challenges ENSG00000134982 ENSG00000168036 ENSG00000146648 PMC4329815__F3 Signaling pathways implicated in hyperstimulation of macropinocytosis and vacuolization of macropinosome-derived compartments ENSG00000149269 ENSG00000165527 PMC8467255__F4 Biological Significance of the Protein Changes Occurring in the Cerebrospinal Fluid of Alzheimer’s Disease Patients: Getting Clues from Proteomic Studies ENSG00000138075 ENSG00000135218 ENSG00000130164 ENSG00000110244 ENSG00000172350 ENSG00000160179 PMC7760556__F1 Possible pathways for immunogenic activation in response to autologous iPSCs-whole cell vaccines PMC4065631__F2 Ligand bias prevents class equality among beta-blockers ENSG00000081181 ENSG00000118520 PMC8432812__F5 Proteogenomic analysis of pancreatic cancer subtypes ENSG00000117020 ENSG00000065526 ENSG00000198435 ENSG00000134982 ENSG00000198793 ENSG00000050165 ENSG00000104371 ENSG00000164327 ENSG00000108375 ENSG00000141564 ENSG00000105669 ENSG00000135605 PMC5825871__F9 Role of Gpr161 in forelimb initiation, limb patterning and skeletal morphogenesis ENSG00000143147 ENSG00000070193 ENSG00000106571 ENSG00000164690 ENSG00000163501 ENSG00000089225 PMC10525532__F4 Thioredoxin/Glutaredoxin Systems and Gut Microbiota in NAFLD: Interplay, Mechanism, and Therapeutical Potential ENSG00000162711 ENSG00000125538 ENSG00000265972 PMC3879708__F2 Upstream nutrient signaling to mTORC1 and AMPK PMC8507803__F2 Good Cholesterol Gone Bad? HDL and COVID-19 ENSG00000042832 ENSG00000005421 ENSG00000160179 PMC3966329__F1 Regulation of autophagy by ARV ENSG00000144895 ENSG00000112561 PMC8009859__F1 Illustration of proposed MB related proteins/pathways described in this review. (i) Conventional MB-related signaling pathways ENSG00000291971 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000185591 ENSG00000128602 ENSG00000113448 PMC8474995__F1 Is there a place for cellular therapy in depression? ENSG00000162711 ENSG00000145321 ENSG00000132693 PMC5657612__F10 The neurovascular unit coming of age: a journey through neurovascular coupling in health and disease ENSG00000135218 ENSG00000073921 ENSG00000171885 PMC8172449__F1 NAD metabolome and metabolic pathways ENSG00000105835 ENSG00000162882 ENSG00000123572 ENSG00000130649 ENSG00000173614 ENSG00000163382 ENSG00000183077 ENSG00000213995 PMC5851940__F5 Highlighted genes to represent a single pathway ENSG00000169896 ENSG00000070831 ENSG00000150093 ENSG00000115232 ENSG00000135605 ENSG00000121966 PMC5851940__F1 Biological pathway of Leukocyte Transendothelial Migration () ENSG00000292348 ENSG00000101146 ENSG00000166086 ENSG00000183864 ENSG00000154721 ENSG00000135605 ENSG00000154096 PMC7949067__F3 Relevant pathways of the unfolded protein response (UPR) ENSG00000002330 ENSG00000144895 ENSG00000100219 PMC7369379__F7 C-P-T network of top 20 pathway ENSG00000108691 ENSG00000177606 ENSG00000173039 ENSG00000213341 ENSG00000104368 PMC5432641__F2 Nucleotide excision repair and the ATR-CHK1-mediated DNA damage checkpoint ENSG00000175054 ENSG00000164053 ENSG00000111602 ENSG00000136936 PMC10965438__F1 Nanomaterials modulating TAMs for the treatment of GC ENSG00000177575 ENSG00000214285 ENSG00000168610 ENSG00000158050 PMC5980186__F5 Proposed model describing the regulatory pathway between Smad7 and hepcidin expression in hepatocytes ENSG00000170365 ENSG00000137834 ENSG00000010704 ENSG00000095739 PMC10965438__F6 Nanomaterials modulating TAM polarization for the treatment of HCC via the STAT signaling pathway ENSG00000177575 ENSG00000115415 ENSG00000168610 PMC6097550__F1 NRAS mutant melanoma: an overview for the clinician for melanoma management ENSG00000135446 ENSG00000105810 PMC10965438__F7 Nanomaterials modulating TAMs polarization for the treatment of HCC via the NFKB signaling pathway ENSG00000164430 ENSG00000115415 ENSG00000187554 ENSG00000214285 PMC5429649__F11 The mechanism of Salvia fruticosa-induced relaxation of rat isolated aorta ENSG00000166278 PMC6154840__F1 PKCι drives both common and lineage-specific oncogenic pathways in lung cancer ENSG00000163435 ENSG00000114346 ENSG00000149269 ENSG00000166670 ENSG00000164690 ENSG00000128602 PMC5976231__F5 Vascular wall resident Sca-1+ progenitor cell migration in response to chemokines and lipoproteins ENSG00000108691 ENSG00000070831 ENSG00000163739 ENSG00000100985 ENSG00000121807 ENSG00000168610 PMC10846380__F6 CK1A degradation by FPFT-2216 and subsequent p53 pathway activation and CBM complex/NFKB pathway inhibition ENSG00000167986 ENSG00000139842 ENSG00000113851 ENSG00000198286 PMC11786022__F7 Mechanism of TGFB activates cancer metastasis potential by inducing metabolic reprogramming and bioenergetic adaptation ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC3572906__F3 Microbial Cell Components Induced Tolerance to Flagellin-Stimulated Inflammation through Toll-Like Receptor Pathways in Intestinal Epithelial Cells ENSG00000169245 ENSG00000170458 ENSG00000177606 ENSG00000095015 ENSG00000134070 ENSG00000172936 ENSG00000130159 ENSG00000168040 ENSG00000150455 ENSG00000127191 ENSG00000010671 PMC12135143__S1 Biosynthetic pathway of IMP (Adapted with permission ENSG00000146676 PMC8192774__F3 Differential methylation of G-protein coupled receptor signaling genes in gastrointestinal neuroendocrine tumors ENSG00000186049 ENSG00000237110 ENSG00000285087 ENSG00000284754 ENSG00000198053 ENSG00000115425 ENSG00000133574 ENSG00000170956 ENSG00000173627 ENSG00000185982 ENSG00000146378 ENSG00000180210 ENSG00000100142 ENSG00000007402 ENSG00000112299 ENSG00000143632 ENSG00000167701 ENSG00000168263 ENSG00000173080 ENSG00000105176 ENSG00000174417 ENSG00000185479 ENSG00000285109 ENSG00000127955 ENSG00000163736 ENSG00000157005 ENSG00000139648 ENSG00000274665 ENSG00000112303 ENSG00000291748 ENSG00000113356 ENSG00000168081 ENSG00000276838 ENSG00000135569 ENSG00000146383 PMC12016470__F8 Sildenafil promotes osteogenic differentiation of hMSCs and suppresses bone loss by affecting TGFB signaling PMC5322168__F5 Induction of IL-21 in Peripheral T Follicular Helper cells is Indicator of Influenza Vaccine Response in Previously Vaccinated HIV-Infected Pediatric Cohort ENSG00000291603 ENSG00000152495 ENSG00000120875 ENSG00000170558 ENSG00000020633 ENSG00000103522 ENSG00000049768 ENSG00000168610 ENSG00000121966 ENSG00000069667 ENSG00000169245 ENSG00000138378 ENSG00000111537 ENSG00000188404 ENSG00000126353 ENSG00000283060 ENSG00000131196 PMC9264955__F6 Prognostic and Predictive Role of Body Composition in Metastatic Neuroendocrine Tumor Patients Treated with Everolimus: A Real-World Data Analysis ENSG00000106070 ENSG00000155792 ENSG00000167965 PMC4740345__F3 Sirolimus and CNI impact on insulin signaling pathway ENSG00000100811 ENSG00000169047 PMC5322168__F4 Induction of IL-21 in Peripheral T Follicular Helper cells is Indicator of Influenza Vaccine Response in Previously Vaccinated HIV-Infected Pediatric Cohort ENSG00000134460 ENSG00000133056 ENSG00000020633 ENSG00000103522 ENSG00000019582 ENSG00000138378 ENSG00000111537 ENSG00000115415 ENSG00000186716 ENSG00000188404 ENSG00000164136 ENSG00000113520 ENSG00000132256 ENSG00000126353 ENSG00000168685 PMC3648498__F3 Alzheimer’s disease pathway from the KEGG database ENSG00000132906 ENSG00000291983 ENSG00000142192 ENSG00000002330 ENSG00000168040 ENSG00000119912 ENSG00000164305 PMC7305909__F1 Virus-based and host-based targets against the coronavirus replication cycle ENSG00000140564 ENSG00000197635 ENSG00000130234 ENSG00000184012 PMC12102949__F2 Illustrates Various Molecular Mechanisms Facilitating the Formation and Survival of DTPs under Targeted Therapy and Immunotherapy ENSG00000147162 ENSG00000198793 ENSG00000179750 ENSG00000168036 ENSG00000139352 ENSG00000117713 ENSG00000141867 ENSG00000143379 ENSG00000167468 ENSG00000015520 ENSG00000125686 ENSG00000177084 ENSG00000127616 PMC12102949__F3 Multiple Cross-linking Mechanisms among Tumor Cells or/and the Surrounding Environment Sustain the Formation and Persistence of DTPs under Targeted Therapy and Immunotherapy ENSG00000139193 ENSG00000019991 ENSG00000107562 ENSG00000111537 ENSG00000160867 ENSG00000163739 ENSG00000198793 ENSG00000140285 ENSG00000168036 ENSG00000138315 PMC10932085__F1 TRPs modulate inflammation in immune cells ENSG00000162711 ENSG00000092439 ENSG00000144935 ENSG00000115415 ENSG00000198793 ENSG00000137672 ENSG00000070985 ENSG00000049768 ENSG00000175104 ENSG00000138741 ENSG00000168610 ENSG00000196689 PMC10932085__F2 TRPs modulate anti-inflammation in immune cells ENSG00000072315 ENSG00000196689 PMC6824679__F2 Synthesis of phosphatidylinositol and acyl chain remodelling ENSG00000042832 ENSG00000173599 ENSG00000198670 ENSG00000184207 ENSG00000144559 ENSG00000273592 PMC5103281__F2 Mechanistic cycle for silyl-mediated cross-coupling PMC4295872__F8 Breast Cancer Genes PSMC3IP and EPSTI1 Play a Role in Apoptosis Regulation ENSG00000132906 ENSG00000002330 ENSG00000133106 ENSG00000131470 ENSG00000168040 ENSG00000146648 ENSG00000064012 ENSG00000164305 PMC4999690__F1 GM-CSF and IL-6 signaling ENSG00000136807 ENSG00000100985 ENSG00000168610 PMC6356072__F4 Protein-protein interaction networks among differentially expressed proteins ENSG00000265681 ENSG00000162433 ENSG00000112499 ENSG00000160710 ENSG00000138071 ENSG00000116962 ENSG00000116688 ENSG00000112699 ENSG00000104131 ENSG00000197635 ENSG00000143878 ENSG00000280495 ENSG00000197102 ENSG00000143569 ENSG00000161970 ENSG00000104408 ENSG00000165264 ENSG00000178127 ENSG00000186834 ENSG00000175390 ENSG00000136448 ENSG00000047410 ENSG00000167671 ENSG00000173638 ENSG00000110931 ENSG00000117054 ENSG00000173950 ENSG00000131876 ENSG00000126803 ENSG00000168461 ENSG00000136153 ENSG00000050405 ENSG00000116120 ENSG00000034693 ENSG00000231247 ENSG00000182712 ENSG00000078668 ENSG00000119596 ENSG00000172340 ENSG00000175334 ENSG00000159685 ENSG00000088035 ENSG00000122873 ENSG00000105426 ENSG00000173166 ENSG00000163820 ENSG00000171262 ENSG00000069275 ENSG00000107959 ENSG00000164070 ENSG00000103356 ENSG00000101152 ENSG00000157500 ENSG00000067704 ENSG00000187902 ENSG00000292234 ENSG00000164764 ENSG00000134717 ENSG00000223953 ENSG00000176087 ENSG00000167378 ENSG00000106077 ENSG00000035141 ENSG00000085719 ENSG00000122033 ENSG00000126878 ENSG00000196712 ENSG00000141741 ENSG00000136522 ENSG00000185633 ENSG00000173546 ENSG00000164163 ENSG00000117226 ENSG00000171992 ENSG00000125246 ENSG00000154146 ENSG00000152556 ENSG00000143553 ENSG00000059804 ENSG00000162493 ENSG00000169599 ENSG00000163631 ENSG00000105894 ENSG00000138744 ENSG00000121410 ENSG00000172534 ENSG00000100412 ENSG00000004487 ENSG00000130402 ENSG00000171560 ENSG00000021776 ENSG00000010379 ENSG00000162704 ENSG00000115486 ENSG00000096872 ENSG00000157766 ENSG00000170855 ENSG00000155660 ENSG00000168924 ENSG00000122971 PMC5288241__F2 Prostate cancer and the unfolded protein response ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC12200665__F9 TPA-induced activation of a PKCD/RIPK4/IRF6 signaling pathway inducing lytic EBV reactivation and epithelial cell differentiation in EBV-infected NOKs ENSG00000136826 PMC4066235__F4 microRNAs in Cancer Cell Response to Ionizing Radiation ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000123374 PMC4066235__F5 microRNAs in Cancer Cell Response to Ionizing Radiation ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000134057 PMC4066235__F7 microRNAs in Cancer Cell Response to Ionizing Radiation ENSG00000132906 ENSG00000168040 ENSG00000064012 PMC2721360__F2 Colorectal cancer cells share the WNT pathway in response to growth suppression by APHS-mediated COX-2 inhibition ENSG00000156076 ENSG00000116044 ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000263238 PMC3488108__F1 Immune-Neuroendocrine Integration at the Adrenal Gland: Cytokine Control of the Adrenomedullary Transcriptome ENSG00000111537 ENSG00000168610 PMC3014093__F3 Upper panel ENSG00000105486 ENSG00000165392 PMC6991964__F8 EphA2 contributes to disruption of the blood-brain barrier in cerebral malaria ENSG00000142627 ENSG00000108691 ENSG00000226275 PMC12049823__F1 Genetic regulation of SPP1 regulated by TFs and the signaling pathway in disease ENSG00000026508 ENSG00000168036 ENSG00000168610 PMC6288187__F1 Vasorin 3D structure: Cartoon representation of the structure model of Vasn predicted by RaptorX (http://raptorx.uchicago.edu/) ENSG00000274334 ENSG00000133961 ENSG00000137845 PMC5951947__F4 An illustration of the PI3K mutant, ER+ breast cancer network ENSG00000002330 ENSG00000135446 ENSG00000136997 ENSG00000123374 ENSG00000105810 ENSG00000171791 ENSG00000140443 PMC7187888__F6 Danqi Pill (DQP) targeted on HIF-1A/PGC-1A signaling pathway and finally elevated cardiac energy metabolism in the failing heart ENSG00000134086 ENSG00000175567 ENSG00000106459 PMC7189569__F4 TNF signalling pathway ENSG00000110514 ENSG00000102871 ENSG00000131323 ENSG00000120868 ENSG00000168040 ENSG00000127191 ENSG00000073756 PMC10418884__F10 Regulatory pathway of GR ENSG00000291971 ENSG00000145321 PMC7390836__F4 DSGs That Are Driver Genes of the CRC Pathway(A) Mapping of DSGs in the CRC pathway from KEGG ENSG00000157554 ENSG00000132906 ENSG00000002330 ENSG00000134982 ENSG00000109321 ENSG00000138798 ENSG00000198793 ENSG00000115904 ENSG00000108443 ENSG00000169032 ENSG00000164305 ENSG00000113318 ENSG00000136997 ENSG00000095002 ENSG00000146648 ENSG00000122008 PMC8976061__F4 Biosynthesis of the phosphonate antibiotic argolaphos A (3) ENSG00000162551 ENSG00000163295 ENSG00000163286 PMC4066235__F3 microRNAs in Cancer Cell Response to Ionizing Radiation ENSG00000146648 PMC5585627__F3 Sphingosine-1-phosphate (S1P) in estrogen receptor- (ER-) positive breast cancer ENSG00000138798 ENSG00000198793 ENSG00000103222 ENSG00000118777 ENSG00000146648 PMC10522371__F7 KIF18A improves migration and invasion of colorectal cancer (CRC) cells through inhibiting PTEN signaling ENSG00000087245 ENSG00000121621 ENSG00000100985 PMC5442653__F3 Potential usage of nanoparticles for splenic targeting ENSG00000117020 ENSG00000167461 ENSG00000198793 PMC8234716__F3 Withaferin A and Its Derivatives in the Management of Alzheimer’s Disease: Recent Trends and Future Perspectives ENSG00000162711 ENSG00000162692 PMC8234716__F2 Withaferin A and Its Derivatives in the Management of Alzheimer’s Disease: Recent Trends and Future Perspectives ENSG00000150782 ENSG00000115415 ENSG00000168610 PMC7840310__F6 Cell cycle program in cell death and metamorphosis ENSG00000087245 ENSG00000136457 ENSG00000135218 ENSG00000110799 ENSG00000157227 ENSG00000026508 ENSG00000100985 PMC4818578__F1 NADPH oxidases: key modulators in aging and age-related cardiovascular diseases? ENSG00000127445 ENSG00000140443 PMC8104092__F6 G-Protein-Coupled Receptor and Ion Channel Genes Used by Influenza Virus for Replication ENSG00000291971 ENSG00000116741 PMC8455272__F8 TWEAK Signaling Pathway Blockade Slows Cyst Growth and Disease Progression in Autosomal Dominant Polycystic Kidney Disease ENSG00000260314 ENSG00000161921 ENSG00000137077 ENSG00000164400 ENSG00000118520 ENSG00000007171 PMC8104092__F7 G-Protein-Coupled Receptor and Ion Channel Genes Used by Influenza Virus for Replication ENSG00000173599 ENSG00000010671 PMC7198260__F2 Ectopic lipids in insulin resistance ENSG00000171105 ENSG00000169047 ENSG00000173599 PMC4818578__F2 NADPH oxidases: key modulators in aging and age-related cardiovascular diseases? ENSG00000198793 ENSG00000086991 ENSG00000171759 ENSG00000162692 PMC6974395__F3 Fumarate hydratase in cancer: a multifaceted tumour suppressor ENSG00000178096 ENSG00000182511 ENSG00000100412 ENSG00000136003 ENSG00000169599 ENSG00000079999 PMC6825568__F7 Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to Chemotherapy by Abrogating the TopBP1/ATR-Mediated DNA Damage Response ENSG00000175054 PMC8104092__F5 G-Protein-Coupled Receptor and Ion Channel Genes Used by Influenza Virus for Replication ENSG00000076864 ENSG00000291971 ENSG00000168610 PMC9410784__F2 Correlation of PM2.5 Exposure with Acute Attack and Steroid Sensitivity in Asthma PMC9221191__F2 Lethal and Non-Lethal Functions of Caspases in the DNA Damage Response ENSG00000168040 ENSG00000026103 PMC8004373__F7 Interaction network of CXCR family proteins (cBioPortal) ENSG00000163464 ENSG00000159921 ENSG00000114450 ENSG00000159899 ENSG00000121879 ENSG00000116096 ENSG00000144476 PMC8932232__F1 Store-operated Ca2+ entry in cardiovascular disease ENSG00000167323 ENSG00000293604 PMC7538683__F5 Bioinformatics analysis and experimental validation of TTK as a biomarker for prognosis in non-small cell lung cancer ENSG00000145604 ENSG00000184990 ENSG00000149311 ENSG00000175054 ENSG00000275679 ENSG00000065833 ENSG00000132646 ENSG00000123374 ENSG00000277273 ENSG00000276876 ENSG00000119125 PMC4494932__F6 Hepatitis B virus X protein induces expression of alpha-fetoprotein and activates PI3K/mTOR signaling pathway in liver cells ENSG00000291971 ENSG00000198793 ENSG00000081051 ENSG00000121966 PMC9623297__F2 Regulatory roles of circular RNAs via autophagy in ischemic stroke PMC5056854__F5 PPAR signaling pathway upregulated in LCMUFA group compared to control (FDR < 0.01) and olive oil group (FDR < 0.01) ENSG00000150991 ENSG00000100979 PMC11020458__F4 Direct osteogenic effects and mechanisms of RE NMs ENSG00000170365 ENSG00000189319 ENSG00000134982 ENSG00000168036 ENSG00000167074 ENSG00000284770 PMC7379200__F3 MicroRNA (miRNA) regulation in the maintenance of male hormonal balance ENSG00000063978 ENSG00000106571 ENSG00000090863 ENSG00000143995 PMC4365602__F7 This schematic shows the numerous pro-inflammatory mediators produced by peri-implant tissue and immune cells reacting to implant debris, which can negatively affect bone turnover ENSG00000150782 ENSG00000125538 PMC3171751__F3 Altered gene expression during pressure overload hypertrophy ENSG00000110721 ENSG00000141384 ENSG00000181690 ENSG00000168610 ENSG00000100749 ENSG00000156127 ENSG00000177606 ENSG00000158796 ENSG00000073734 ENSG00000080618 ENSG00000004897 ENSG00000188130 ENSG00000105246 ENSG00000108821 ENSG00000130513 ENSG00000026103 PMC11950169__F6 Key mechanisms involved in TTFields-induced activation of AKT ENSG00000002330 ENSG00000170558 PMC5107467__F7 Amide-linked local anesthetics induce apoptosis through apoptotic pathways (the extrinsic death receptor pathway and the intrinsic mitochondrial pathway) and MAPK pathways in human non-small-cell lung cancer cells ENSG00000168040 PMC11815446__F1 Metabolic pathway of Clopidogrel ENSG00000165841 ENSG00000197408 ENSG00000140505 PMC7038167__F5 Graph of genes and processes involved in the pathway 04110: Cell cycle ENSG00000145604 ENSG00000094804 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000205250 ENSG00000277273 ENSG00000117399 ENSG00000276876 PMC3107509__F1 Wnt signaling pathways ENSG00000168036 ENSG00000125084 PMC8197977__F3 Nicotinamide N-Methyltransferase in Acquisition of Stem Cell Properties and Therapy Resistance in Cancer ENSG00000105835 ENSG00000138356 PMC3989729__F7 A schematic diagram illustrating the interplay between TLX and the BMP-SMAD signaling pathway in the regulation of neurogenesis and astrogenesis ENSG00000131095 PMC8438703__F1 Understanding microglial diversity and implications for neuronal function in health and disease ENSG00000167601 ENSG00000168329 ENSG00000137845 PMC2567511__F1 The tetrapyrrole pathway in plants showing intermediates and genes analyzed in this study ENSG00000144410 ENSG00000126088 ENSG00000188690 ENSG00000127948 PMC9159374__F3 Amelioratory Effect of Resistant Starch on Non-alcoholic Fatty Liver Disease via the Gut-Liver Axis ENSG00000042832 ENSG00000136869 ENSG00000131096 PMC8197977__F1 Nicotinamide N-Methyltransferase in Acquisition of Stem Cell Properties and Therapy Resistance in Cancer ENSG00000105835 ENSG00000123572 ENSG00000278488 PMC6542994__F1 Genetic Predisposition for Immune System, Hormone, and Metabolic Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome ENSG00000158825 PMC5624455__F4 Leukocyte extravasation signaling pathway altered by a high-fat-diet, Taeumjowitang, and green tea in the epididymal white adipose tissue ENSG00000026508 ENSG00000150093 ENSG00000154721 ENSG00000115232 ENSG00000089159 PMC9229764__F2 Variation in the Humoral Immune Response Induced by the Administration of the BNT162b2 Pfizer/BioNTech Vaccine: A Systematic Review ENSG00000134982 ENSG00000130234 ENSG00000026103 PMC9471015__F1 Applications and prospects of genome editing in plant fatty acid and triacylglycerol biosynthesis ENSG00000173599 ENSG00000198670 PMC5881172__F1 Unfolded protein response ENSG00000128272 ENSG00000185591 ENSG00000100219 ENSG00000167182 PMC7830093__F1 Comparative view of wild-type p53 function in ESC maintenance, differentiation, and somatic-cell reprogramming of human and mouse: ESC maintenance: p53 is maintained in an inactive state in both human and mouse ESCs ENSG00000131914 ENSG00000087586 ENSG00000122779 ENSG00000096717 ENSG00000136826 ENSG00000198625 PMC7184931__F1 This schematic diagram shows the metabolic pathways controlling activation and lineage specification in the immune system ENSG00000124479 ENSG00000135218 ENSG00000115902 ENSG00000130164 ENSG00000026508 ENSG00000049768 ENSG00000168610 ENSG00000106546 ENSG00000168118 PMC9328443__F7 SNPeffect: identifying functional roles of SNPs using metabolic networks ENSG00000197429 ENSG00000082212 PMC7184931__F2 Metabolic control of T-cell related to tryptophan metabolism ENSG00000134982 ENSG00000198793 ENSG00000106546 PMC9328443__F6 SNPeffect: identifying functional roles of SNPs using metabolic networks ENSG00000112977 PMC9410115__F1 Pathophysiology of Coagulation and Emerging Roles for Extracellular Vesicles in Coagulation Cascades and Disorders ENSG00000110799 ENSG00000134982 ENSG00000122194 PMC9328443__F3 SNPeffect: identifying functional roles of SNPs using metabolic networks PMC6278486__F3 High-energy donor UDP-GlcNAc is provided by the hexosamine biosynthetic pathway (HBP) and is connected to UDP-GalNAc and CMP-NeuAc ENSG00000159921 ENSG00000170191 ENSG00000147162 ENSG00000198408 ENSG00000095380 PMC4516432__F5 Models for pre-miRNA uridylation by TUT7 Pre-miRNA uridylation by TUT7/4/2 in microRNA biogenesis pathway ENSG00000083223 ENSG00000134744 ENSG00000123908 PMC6345743__F5 Comparing ECM-receptor interaction pathway for (a) DA and (b) non-DA neurons based on DEGs and DEmiR ENSG00000168748 ENSG00000112280 ENSG00000090402 ENSG00000058085 ENSG00000173039 ENSG00000150093 ENSG00000169231 ENSG00000137801 ENSG00000185518 ENSG00000053747 ENSG00000105664 ENSG00000136457 ENSG00000069482 ENSG00000118785 ENSG00000188157 ENSG00000108821 ENSG00000026103 PMC6311498__F1 Cartoon illustrating the intracellular distribution of ATP7A, ATP7B, and DBH ENSG00000123191 ENSG00000123454 PMC3132612__F2 The major signal transduction pathway in the ER stress response ENSG00000128272 ENSG00000100219 ENSG00000127191 PMC7184931__F3 cGAS-STING-IFN pathway activation in SLE ENSG00000164430 ENSG00000173638 PMC2797892__F10 Pathway induction after pathophysiologic stimulation of BSMC by three coordinate stimuli: strain, hypoxia, and damaged matrix ENSG00000198793 ENSG00000168610 PMC3677627__F5 Molecular network based on some key metabolites reversed by resina draconis or isosorbide dinitrate treatment ENSG00000170962 ENSG00000125388 ENSG00000183840 ENSG00000128655 ENSG00000288474 ENSG00000178473 PMC5742900__F3 Gene Expression, Oxidative Stress, and Senescence of Primary Coronary Endothelial Cells Exposed to Postprandial Serum of Healthy Adult and Elderly Volunteers after Oven-Cooked Meat Meals ENSG00000119912 ENSG00000106546 PMC5742900__F4 p53 signaling pathway and related significant changes observed in response to postprandial serum (orange: upregulated compared to fasting serum; green: downregulated compared to fasting serum) ENSG00000149311 ENSG00000175054 ENSG00000108557 ENSG00000198793 ENSG00000136997 ENSG00000123374 ENSG00000112378 ENSG00000196470 ENSG00000026103 PMC5887474__F3 Canonical p53 DNA damage response pathway ENSG00000134057 ENSG00000132646 ENSG00000087586 ENSG00000116717 ENSG00000166851 ENSG00000124762 PMC3067813__F7 Model of proposed HEB, GATA3, and Notch1 interactions ENSG00000148400 ENSG00000107485 ENSG00000165702 PMC5426948__F2 Proposed signalling pathway showing that genetic loci deregulated through altered methylation in Beckwith-Wiedeman syndrome are upstream of pheochromocytoma-paraganglioma susceptibility genes ENSG00000133895 ENSG00000134086 ENSG00000169291 ENSG00000111837 ENSG00000198793 ENSG00000136997 ENSG00000196712 PMC9425815__F1 Involvement of host microRNAs in flavivirus-induced neuropathology: An update ENSG00000137834 ENSG00000183735 ENSG00000100906 ENSG00000157625 ENSG00000121807 PMC9425815__F4 Involvement of host microRNAs in flavivirus-induced neuropathology: An update ENSG00000171150 ENSG00000175104 ENSG00000156273 PMC3675946__F6 Cell wall integrity (CWI) signaling pathway with transcriptomic expression changes during limonene stress ENSG00000149489 ENSG00000063515 PMC9425815__F3 Involvement of host microRNAs in flavivirus-induced neuropathology: An update ENSG00000123091 ENSG00000088888 ENSG00000118503 ENSG00000171150 ENSG00000148400 ENSG00000115415 ENSG00000170855 ENSG00000131323 ENSG00000125347 ENSG00000168610 ENSG00000101695 PMC7904692__F1 Antiviral pathways in silkworm ENSG00000146648 ENSG00000123908 PMC6713920__F3 The schematic flow of biosynthetic pathway of DNJ in S ENSG00000039537 ENSG00000148926 ENSG00000166278 PMC8108589__F3 LRP-1 modulates neurodegeneration and neuroregeneration ENSG00000102871 ENSG00000056558 ENSG00000168040 ENSG00000127191 PMC7534062__F8 Schematic diagram depicting the effects and mechanisms of TPH-1 against renal fibrosis and the regulation of PAA on TPH-1 expression ENSG00000134982 ENSG00000129167 ENSG00000168036 PMC8108589__F1 Proinflammatory pathways regulated by LRP-1: The interaction between LRP-1 and ApoE represses the formation of IRAK1–TRAF6 complex and therefore the NFKB-mediated pathway ENSG00000108691 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC8667344__F1 Interleukin-5 (IL-5) Therapy Prevents Allograft Rejection by Promoting CD4+CD25+ Ts2 Regulatory Cells That Are Antigen-Specific and Express IL-5 Receptor ENSG00000134982 ENSG00000137265 ENSG00000107485 ENSG00000049768 PMC7074087__F7 PC inhibitor attenuated glycolytic shift and metabolic reprogramming in pulmonary hypertension ENSG00000173599 ENSG00000171759 PMC5710802__F3 RLR-mediated RNA sensing pathways ENSG00000088888 ENSG00000102871 ENSG00000107201 ENSG00000168040 ENSG00000276561 PMC8774167__F1 Autophagy Regulation on Cancer Stem Cell Maintenance, Metastasis, and Therapy Resistance ENSG00000198793 ENSG00000144848 PMC11660554__F5 Alterations in the HSV-1-associated host antiviral signaling pathway in HGFs ENSG00000088888 ENSG00000276561 PMC6410042__F6 Pathway analysis for PRR and IFN signaling ENSG00000213928 ENSG00000285321 ENSG00000089127 ENSG00000157601 ENSG00000185745 ENSG00000125347 ENSG00000106100 ENSG00000111816 ENSG00000230034 ENSG00000068079 ENSG00000111537 ENSG00000115415 ENSG00000185201 ENSG00000148798 ENSG00000136869 ENSG00000172936 ENSG00000142089 ENSG00000135828 ENSG00000164342 PMC12241104__F1 Biosynthesis of shikimate ENSG00000150787 PMC8651602__F2 Perspectives, past, present and future: the proline cycle/proline-collagen regulatory axis ENSG00000122966 ENSG00000100033 PMC3316122__F2 Schematic model depicting activation of the AIM2 inflammasome by F ENSG00000163568 ENSG00000125538 ENSG00000142166 PMC8954241__F4 Toxic Mechanism and Biological Detoxification of Fumonisins ENSG00000102871 ENSG00000198793 ENSG00000168040 ENSG00000057663 ENSG00000026103 PMC7885408__F9 Role of SIK1 in the transition of acute kidney injury into chronic kidney disease ENSG00000281324 ENSG00000142178 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC10296498__F1 IL-33/ST2 signaling pathway activation ENSG00000137033 ENSG00000172936 ENSG00000175104 PMC2262896__F6 Interferon signaling ENSG00000213928 ENSG00000115415 ENSG00000185745 ENSG00000185885 ENSG00000125347 ENSG00000230034 PMC2262896__F4 TCR signaling pathway ENSG00000117650 ENSG00000107338 ENSG00000110395 ENSG00000137601 ENSG00000213658 ENSG00000010810 ENSG00000148204 ENSG00000113263 ENSG00000132693 ENSG00000135605 PMC8225190__F6 Involvement of mTOR Pathways in Recovery from Spinal Cord Injury by Modulation of Autophagy and Immune Response ENSG00000112561 PMC9113089__F2 Glioma and the gut–brain axis: opportunities and future perspectives ENSG00000125538 ENSG00000131096 PMC2311292__F2 Pathway representation of all the tryptophan related genes analyzed ENSG00000143149 ENSG00000072210 ENSG00000168806 ENSG00000206562 ENSG00000205629 ENSG00000142453 ENSG00000105953 ENSG00000105607 ENSG00000164305 ENSG00000291944 PMC7746821__F1 Summary of drug resistance in tumor immunotherapy ENSG00000149311 ENSG00000163939 ENSG00000089692 ENSG00000181847 ENSG00000272398 PMC8110656__F8 I2 imidazoline receptor modulation protects aged SAMP8 mice against cognitive decline by suppressing the calcineurin pathway ENSG00000002330 ENSG00000131095 PMC7460823__F1 Representation of the metabolites and related pathways involved in the Epithelial-Mesenchymal transition (EMT) process in cancer ENSG00000237110 ENSG00000124216 ENSG00000146385 ENSG00000136869 ENSG00000100985 ENSG00000131023 ENSG00000084774 PMC9396337__F9 Electroacupuncture improves TBI dysfunction by targeting HDAC overexpression and BDNF-associated Akt/GSK-3B signaling ENSG00000171720 ENSG00000131095 PMC3523725__F7 PPARG COUNTERACTS LRP1-INDUCED VASCULAR CALCIFICATION BY INHIBITING A WNT5A SIGNALING PATHWAY ENSG00000125398 PMC10779188__F1 BRAF signaling pathway and targeted therapies in the BRAF pathway ENSG00000157764 ENSG00000198793 PMC12130703__F0 TRIM21 promotes type I interferon by inhibiting the autophagic degradation of STING via p62/SQSTM1 ubiquitination in systemic lupus erythematosus ENSG00000132109 ENSG00000164430 PMC9707496__F2 Dysregulation of FBW7 in malignant lymphoproliferative disorders ENSG00000005339 ENSG00000168610 PMC8959654__F1 LncRNAs Mediating Wnt/Beta-Catenin Signaling in HCC ENSG00000168036 PMC8959654__F2 LncRNAs Mediating Wnt/Beta-Catenin Signaling in HCC ENSG00000168036 PMC8959654__F3 LncRNAs Mediating Wnt/Beta-Catenin Signaling in HCC PMC10341994__F8 Mechanism of AM polarization toward M1 phenotype and early apoptosis induced by rLLB exposure ENSG00000171791 PMC12232702__F5 AKT phosphorylates USP4 ENSG00000136535 ENSG00000175104 ENSG00000127191 PMC5710802__F1 cGAS-STING pathway senses cytosolic dsDNA ENSG00000164430 PMC6562601__F1 De novo pyrimidine and purine synthesis pathways ENSG00000128050 ENSG00000102967 ENSG00000084774 PMC9569764__F8 Developmental Transcriptome Analysis of Red-Spotted Apollo Butterfly, Parnassius bremeri ENSG00000144063 ENSG00000026103 PMC2783859__F3A Identification of Actively Translated mRNA Transcripts in a Rat Model of Early Stage Colon Carcinogenesis ENSG00000112576 ENSG00000027075 ENSG00000107404 ENSG00000134982 ENSG00000050748 ENSG00000175592 ENSG00000157240 ENSG00000078304 ENSG00000130164 ENSG00000184524 ENSG00000067606 ENSG00000177606 ENSG00000136997 PMC4667861__F1 Signalling pathways and mechanisms regulated by vagal activation ENSG00000168610 PMC6524401__F1 Overexpression of IL-6 and its potential negative consequences on the viral immune response ENSG00000134982 ENSG00000113520 PMC6522855__F2 Complement pathway ENSG00000196352 ENSG00000117335 ENSG00000244731 ENSG00000166278 ENSG00000117322 ENSG00000182326 ENSG00000236625 PMC5132394__F8 iTRAQ-Based Quantitative Proteomic Comparison of Early- and Late-Passage Human Dermal Papilla Cell Secretome in Relation to Inducing Hair Follicle Regeneration ENSG00000154342 ENSG00000149968 ENSG00000134982 ENSG00000168036 ENSG00000111186 PMC9076740__F2 Maturation of beta cells: lessons from in vivo and in vitro models ENSG00000125166 ENSG00000131473 ENSG00000065833 ENSG00000292099 ENSG00000198793 ENSG00000173599 ENSG00000146701 PMC8576424__F2 GIP Receptor in the CNS for the Pathogenesis of Obesity ENSG00000159224 ENSG00000010310 PMC1779567__F6 Functional dissection of signaling modules in human TReg cells ENSG00000182568 ENSG00000134982 ENSG00000137193 ENSG00000120889 ENSG00000196154 ENSG00000168040 ENSG00000049768 ENSG00000189283 ENSG00000138378 ENSG00000136997 ENSG00000164938 ENSG00000056558 ENSG00000107485 ENSG00000168685 PMC9311382__F1 Gut microbiota in sarcopenia and heart failure ENSG00000158022 ENSG00000198793 ENSG00000115594 ENSG00000140443 PMC6385748__F7 Graphical representation demonstrating the role of PDK4 in obesity-induced MAM formation and skeletal muscle IR ENSG00000150907 ENSG00000169047 PMC2871659__F1 Overall scheme of key genetic and epigenetic events in colorectal tumorigenesis ENSG00000157764 ENSG00000134982 ENSG00000168036 PMC4917669__F2 The MyD88-independent pathway ENSG00000183735 ENSG00000170458 ENSG00000172005 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC4917669__F4 Graphical abstract ENSG00000172936 ENSG00000136869 ENSG00000276561 PMC12146001__F2 Introduction and optimization of lanosterol biosynthesis pathway in E ENSG00000230791 ENSG00000197429 ENSG00000128602 PMC4917669__F1 MyD88-dependent pathway ENSG00000170458 ENSG00000134070 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC9569207__F8 Therapeutic Roles of Cinnamaldehyde against Cardiovascular Diseases ENSG00000136869 PMC4320499__F6 MM patient 3 profile schematic ENSG00000110711 ENSG00000148400 ENSG00000095015 ENSG00000168036 ENSG00000168067 ENSG00000151929 ENSG00000171791 ENSG00000139625 ENSG00000173327 ENSG00000164305 ENSG00000124762 ENSG00000168214 ENSG00000135446 ENSG00000123374 ENSG00000185591 PMC5278463__F7 Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism ENSG00000112561 PMC11247557__F9 Pyroptotic macrophages promote proliferation and chemotherapy resistance of peripheral T‐cell lymphoma via TLR4 signaling pathway ENSG00000023445 ENSG00000278718 ENSG00000162711 ENSG00000056558 ENSG00000136869 ENSG00000171791 PMC8921549__F7 Inhibition of Myocardial Cell Apoptosis Is Important Mechanism for Ginsenoside in the Limitation of Myocardial Ischemia/Reperfusion Injury ENSG00000168040 ENSG00000139687 ENSG00000079999 ENSG00000026103 PMC8921549__F3 Inhibition of Myocardial Cell Apoptosis Is Important Mechanism for Ginsenoside in the Limitation of Myocardial Ischemia/Reperfusion Injury ENSG00000168040 ENSG00000139687 ENSG00000026103 PMC8921549__F4 Inhibition of Myocardial Cell Apoptosis Is Important Mechanism for Ginsenoside in the Limitation of Myocardial Ischemia/Reperfusion Injury ENSG00000096717 ENSG00000139687 PMC8921549__F5 Inhibition of Myocardial Cell Apoptosis Is Important Mechanism for Ginsenoside in the Limitation of Myocardial Ischemia/Reperfusion Injury ENSG00000139687 ENSG00000079999 PMC4276460__F7 HSP90 inhibitor NVP-AUY922 enhances TRAIL-induced apoptosis by suppressing the JAK2-STAT3-Mcl-1 signal transduction pathway in colorectal cancer cells ENSG00000168040 ENSG00000168610 PMC7322915__F1 Effect of caffeine on Cdc25 regulation in S ENSG00000163624 ENSG00000113456 ENSG00000134982 PMC6370048__F2 Downstream effectors and upstream regulatory pathways of RKIP ENSG00000100811 ENSG00000157764 ENSG00000148400 ENSG00000170558 ENSG00000168036 ENSG00000162692 ENSG00000168610 ENSG00000121966 ENSG00000156273 PMC5961473__F7 miRNA–gene interaction network.Notes: miRNAs are shown in pink, genes from Gmagenta are shown in magenta and genes from Ggreen are shown in green ENSG00000259207 ENSG00000186340 ENSG00000077157 ENSG00000058668 ENSG00000080573 ENSG00000156475 ENSG00000140416 ENSG00000198947 PMC2048738__F1 Reactions of the Calvin cycle, starch synthesis, photosynthetic carbon oxygenation pathway, triose-P export, and Suc synthesis represented in the model (Supplemental Appendix S1, A and B) ENSG00000261701 ENSG00000159224 ENSG00000115271 PMC11882405__F10 Reversal of chemotherapy resistance in gastric cancer with traditional Chinese medicine as sensitizer: potential mechanism of action ENSG00000168610 PMC2099624__F9 Schematic model of Nrf2 regulation by Keap1 ENSG00000178573 ENSG00000100387 ENSG00000079999 PMC9703913__F2 Cofilin Acts as a Booster for Progression of Malignant Tumors Represented by Glioma ENSG00000070831 ENSG00000122691 ENSG00000149269 ENSG00000163914 ENSG00000067900 ENSG00000155659 PMC3784815__F3 Kidney immune activation against ischemia-reperfusion and transplant injury ENSG00000134982 ENSG00000062485 PMC9371855__F6 Rosin Derivative IDOAMP Inhibits Prostate Cancer Growth via Activating RIPK1/RIPK3/MLKL Signaling Pathway ENSG00000137275 ENSG00000167468 ENSG00000189403 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC4676894__F9 Mechanism-based combinatorial experimental regimens aimed at disrupting known oncogenic cooperation pathways in ABC-DLBCLs ENSG00000104856 ENSG00000170365 ENSG00000186716 ENSG00000136997 ENSG00000137265 ENSG00000172936 ENSG00000171791 ENSG00000168610 ENSG00000198286 PMC7601443__F3 Crosstalk between adipose tissue clock and important signaling targets ENSG00000105835 ENSG00000198793 ENSG00000096717 ENSG00000163884 PMC6314025__F3 Model unifying proteostasis in ER and cytoplasm of Plasmodium falciparum in mechanisms of artemisinin resistance ENSG00000124102 ENSG00000144895 PMC4676894__F5 Proposed model for the postulated functions of STAT1 in HR-DLBCL-NOS ENSG00000111537 ENSG00000115415 PMC4676894__F2 Oncogenic (deregulated) intracellular signaling pathways in germinal center B cell-like (GCB) diffuse large B-cell lymphoma (DLBCL) ENSG00000116815 ENSG00000163914 ENSG00000171791 ENSG00000182162 ENSG00000267534 PMC7905558__F7 Experimental framework ENSG00000087245 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC4676894__F3 Oncogenic (deregulated) intracellular signaling pathways in activated B cell-like (ABC) diffuse large B-cell lymphoma (DLBCL) ENSG00000105369 ENSG00000116815 ENSG00000007312 ENSG00000186716 ENSG00000137265 ENSG00000172936 ENSG00000171791 ENSG00000168610 ENSG00000198286 PMC9644577__F2 Fat storage-inducing transmembrane proteins: beyond mediating lipid droplet formation ENSG00000197296 ENSG00000134982 ENSG00000168036 PMC2663399__F2 DNA Damage Tolerance: When It’s OK to Make Mistakes ENSG00000132646 ENSG00000070950 ENSG00000099864 PMC5549707__F8 4'-Hydroxywogonin suppresses lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages and acute lung injury mice ENSG00000172936 ENSG00000150455 ENSG00000175104 PMC8068170__F1 WNT signaling pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000177606 ENSG00000168036 PMC8534197__F8 Molecular Signature Expands the Landscape of Driver Negative Thyroid Cancers ENSG00000110330 ENSG00000281324 ENSG00000134982 ENSG00000169047 ENSG00000155792 ENSG00000168036 ENSG00000167965 ENSG00000285069 ENSG00000142166 ENSG00000292210 ENSG00000101407 ENSG00000168003 ENSG00000122025 ENSG00000145623 ENSG00000136997 ENSG00000100211 ENSG00000155760 ENSG00000132906 ENSG00000112964 ENSG00000189056 ENSG00000274070 ENSG00000137193 ENSG00000168610 ENSG00000068028 ENSG00000138378 ENSG00000111537 ENSG00000145979 ENSG00000146648 PMC2663399__F5 DNA Damage Tolerance: When It’s OK to Make Mistakes ENSG00000175054 ENSG00000164053 ENSG00000132646 ENSG00000070950 PMC6623974__F2 Functional interaction network analysis ENSG00000108691 ENSG00000011422 ENSG00000164690 ENSG00000162692 ENSG00000127191 PMC1360652__F6 Working model for the effects of 15d-PGJ2 and thiazolidinediones on TNF-stimulated NFKB activation and COX2 expression ENSG00000132170 PMC4615939__F11 Proposed scheme for mechanical stretch-induced VSMC hypertrophy through leptin synthesis, RhoA/ROCK pathway, ROS formation, and GATA-4 nuclear translocation ENSG00000285109 ENSG00000163914 PMC12205666__F8 SiNPs inducing pulmonary genotoxicity and malignant transformation via autophagy dysfunction ENSG00000163961 ENSG00000284099 ENSG00000079999 PMC5378159__F1 Synthesis and metabolism of repressors of SREBP processing and LXR ligands, 24S,25-EC, 25-HC, of the EBI2 ligand 7A,25-diHC and of the RORGt ligand 7B,26-diHC ENSG00000138135 ENSG00000167910 ENSG00000036530 ENSG00000135929 PMC5378159__F3 Synthesis and metabolism of oxysterol modulators of Hh signalling ENSG00000172893 ENSG00000167910 ENSG00000135929 PMC5286373__F2 Hypoxia‐inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype ENSG00000092621 PMC3771080__F1 Pathway analysis depicting cytokine and cytokine receptor interactions relative to position in the cellular environment ENSG00000104689 ENSG00000115008 ENSG00000159128 ENSG00000111537 ENSG00000105329 ENSG00000164136 ENSG00000113520 ENSG00000136689 ENSG00000168685 PMC5286373__F3 Hypoxia‐inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype ENSG00000065911 ENSG00000092621 ENSG00000135069 ENSG00000146733 ENSG00000120254 PMC6009840__F1 Metabolic Reprogramming in Kidney Cancer ENSG00000169710 ENSG00000115419 PMC2933389__F9 Persistent hyperinsulinemic hypoglycemia of infancy: constitutive activation of the mTOR pathway with associated exocrine-islet transdifferentiation and therapeutic implications ENSG00000198793 PMC6009840__F2 Metabolic Reprogramming in Kidney Cancer PMC7760867__F1 Relapse-associated genes and pathways interacting with R-CHOP immunochemotherapy ENSG00000177455 ENSG00000149311 ENSG00000175054 ENSG00000186716 ENSG00000136997 ENSG00000171791 PMC6476918__F1 Canonical and alternative Wnt signaling pathways ENSG00000138795 ENSG00000134982 ENSG00000177606 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC11701040__F2 Mechanisms by which mitochondrial dysfunction drives the development of chemotolerance in colorectal cancer (CRC): mitochondrial dysfunction drives CRC cell proliferation and chemotolerance ENSG00000157764 ENSG00000143761 ENSG00000189401 ENSG00000168036 ENSG00000146410 PMC8264993__F8 AXL kinase-mediated astrocytic phagocytosis modulates outcomes of traumatic brain injury ENSG00000167601 PMC10301029__F1 Tyrosine kinase (EGF pathway) and Wnt/Beta-catenin pathways ENSG00000281324 ENSG00000162337 ENSG00000115415 ENSG00000134982 ENSG00000172602 ENSG00000138798 ENSG00000168036 ENSG00000100985 ENSG00000168610 ENSG00000146648 PMC3640986__F2 Steroid Receptor Coactivator-3 as a Potential Molecular Target for Cancer Therapy ENSG00000125538 ENSG00000169047 ENSG00000140443 PMC10301029__F2 Overlap between the tyrosine kinase pathway, Wnt/Beta-catenin, and prostaglandin inflammation pathways ENSG00000168036 PMC10301029__F3 EMT transition pathway ENSG00000169554 ENSG00000138795 ENSG00000169291 ENSG00000171720 ENSG00000291971 ENSG00000196591 ENSG00000168036 ENSG00000168610 PMC6627503__F2 Mitochondrial antiviral response ENSG00000088888 ENSG00000276561 PMC11965601__F1 LBP in inhibiting retinal cell apoptosis ENSG00000125538 ENSG00000198793 PMC4339376__F10 Effects of Magnolol and Honokiol on Adhesion, Yeast-Hyphal Transition, and Formation of Biofilm by Candida albicans ENSG00000196511 ENSG00000117298 PMC11965601__F3 Flavonoids in inhibiting retinal cell apoptosis PMC7433927__F1 Interrelationships among components of the 1-carbon metabolism pathway (Methionine cycle, Folate cycle, and Transsulfuration pathway) ENSG00000228716 ENSG00000198793 ENSG00000124275 ENSG00000160282 ENSG00000116649 ENSG00000116761 ENSG00000102172 ENSG00000116984 PMC8654269__F1 IRAK1 and IRAK4 as emerging therapeutic targets in hematologic malignancies ENSG00000255833 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC11965601__F6 Autophagy regulation in Lycium barbarum L ENSG00000177169 ENSG00000083290 PMC2678718__F1 Conversion of subendothelial macrophages into cholesterol-laden foam cells is believed to constitute the foundation of the atherosclerotic lesion ENSG00000010810 ENSG00000129226 PMC5032153__F1 Notch signalling pathway ENSG00000122882 ENSG00000128917 PMC8369418__F1 NAD+ in Alzheimer’s Disease: Molecular Mechanisms and Systematic Therapeutic Evidence Obtained in vivo ENSG00000180773 ENSG00000162882 ENSG00000123572 ENSG00000221955 ENSG00000278488 ENSG00000146477 ENSG00000157064 ENSG00000173614 ENSG00000122696 ENSG00000112992 ENSG00000183077 PMC5079664__F1 CDK4-CDK6 protect DNMT1 from autophagy ENSG00000135446 ENSG00000140464 PMC4799531__F1 The central metabolic pathways leading to n-butanol in E PMC5368219__F1 Alterations in histone methylation in pediatric and adult high-grade glioma ENSG00000157764 ENSG00000160679 ENSG00000146648 PMC9382911__F1 Pyruvate as a Potential Beneficial Anion in Resuscitation Fluids ENSG00000173599 PMC11900823__F7 Mechanism of BRD7 inhibiting immune escape of NPC ENSG00000198793 ENSG00000168610 ENSG00000166164 PMC9304652__F2 Research Progress on Structure and Anti-Gynecological Malignant Tumor of Shikonin ENSG00000198793 ENSG00000168610 PMC3191034__F7 Postulated model for GRTH negative autocrine molecular mechanism of regulation of androgen synthesis in Leydig cells ENSG00000113161 PMC8441359__F2 Chronic low‐grade inflammation in heart failure with preserved ejection fraction ENSG00000278718 ENSG00000162711 ENSG00000125538 ENSG00000115594 PMC8478560__F2 Long Noncoding RNAs Regulate the Radioresistance of Breast Cancer ENSG00000166263 ENSG00000128710 ENSG00000002330 ENSG00000076554 ENSG00000168036 PMC4822552__F4 Serum transferrin carrying the xeno-tetrasaccharide NeuAc-Gal-GlcNAc2 is a biomarker of ALG1-CDG ENSG00000069482 ENSG00000033011 ENSG00000163933 PMC3243745__F6 Metabolic pathways illustrating TCDD-elicited changes in the mouse (A) and rat (B) ENSG00000110721 ENSG00000149269 ENSG00000186063 ENSG00000101577 ENSG00000184207 ENSG00000186281 ENSG00000136872 ENSG00000062282 ENSG00000016391 PMC6193072__F1 Canonical NFKB pathway ENSG00000104856 ENSG00000083799 ENSG00000049768 ENSG00000121966 PMC4622839__F1 PIK3/AKT/mTOR signaling pathway in acute myeloid leukemia ENSG00000002330 ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC6348597__F1 The signaling pathway implicated in VIDD development ENSG00000291971 ENSG00000198793 ENSG00000136869 PMC6275407__F2 T helper cell differentiation signaling pathway ENSG00000162594 ENSG00000138378 ENSG00000163235 ENSG00000103522 ENSG00000049768 ENSG00000168610 PMC7667157__F7 ZEB1-activated LINC01123 accelerates the malignancy in lung adenocarcinoma through NOTCH signaling pathway ENSG00000148400 PMC4234172__F2 Signaling pathways employed by CSCs: Distinct combinations of paracrine and juxtracrine signals induce the EMT in different contexts ENSG00000163251 ENSG00000162337 ENSG00000185483 ENSG00000168036 ENSG00000128602 ENSG00000168610 PMC3892554__F2 TRB3 at the crossroads of ER stress and mTORC function ENSG00000128272 ENSG00000144895 ENSG00000198793 PMC9568463__F8 HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress PMC5761485__F1 Biosynthetic pathway of steroid sulfates ENSG00000203859 PMC5445662__F1 Intracellular signaling pathways associated with IR-induced cell death modalities ENSG00000149311 ENSG00000132906 ENSG00000083290 ENSG00000198793 ENSG00000164305 ENSG00000285379 ENSG00000026103 PMC2769199__F8 Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC6027703__F5 Relationship between Beta-catenin, MEN1, and NCOR1 mutations and the Wnt signaling pathway summarized ENSG00000133895 ENSG00000168036 PMC7642974__F9 The autophagy pathway by E3 ubiquitin ligases ENSG00000177169 ENSG00000110497 ENSG00000123395 ENSG00000123240 ENSG00000119401 ENSG00000155792 ENSG00000158828 ENSG00000112561 ENSG00000157954 ENSG00000113851 ENSG00000072803 ENSG00000086758 ENSG00000057663 ENSG00000280616 ENSG00000175104 ENSG00000145782 ENSG00000148356 PMC6120695__F2 Secreted immunomodulatory factors transcriptionally induced by oncogenic Kras signaling ENSG00000081041 ENSG00000163739 ENSG00000169429 PMC5394116__F1 Although a myriad of intracellular signaling is involved in passive therapies, their pathways show some overlap ENSG00000163599 ENSG00000198793 ENSG00000121966 PMC5761026__F1 Simplified scheme for one-carbon metabolism ENSG00000228716 ENSG00000124275 PMC2593475__F1 PI3K/PTEN/Akt/mTOR Pathway ENSG00000002330 ENSG00000198793 PMC2674579__F1 GST-MDA-7 causes PERK-dependent vacuolization and JNK pathway activation in transformed cells that leads to cell death ENSG00000002330 PMC4203662__F1 Targeting the PI3K/AKT/mTOR pathway: potential for lung cancer treatment ENSG00000118515 PMC7192953__F6 Interregulation of the PIKK family members DNA-PKcs and ATM and their downstream substrates in the DDR pathway activated following DSB induction by IR ENSG00000188486 ENSG00000149311 ENSG00000100387 ENSG00000166851 PMC4019000__F1 Dietary Fatty Acids and the Aging Brain ENSG00000171105 ENSG00000005882 ENSG00000281879 ENSG00000119912 ENSG00000105723 PMC7192953__F4 Pathways of DNA double-strand break repair ENSG00000143799 ENSG00000012048 ENSG00000051180 ENSG00000177084 ENSG00000139618 PMC8396177__F1 Neutrophil Extracellular Traps (NETs) in Severe SARS-CoV-2 Lung Disease ENSG00000291971 ENSG00000136869 ENSG00000005381 PMC6120695__F3 Cooperation of Kras-mutant tumor cells with pancreatic stellate cells in tumor microenvironment (TME) immunomodulation ENSG00000169245 ENSG00000107562 ENSG00000168610 PMC3765962__F2 Important molecular pathways and drug targets in RCC ENSG00000134086 ENSG00000198793 ENSG00000128052 ENSG00000037280 PMC9434839__F3 Oxidative stress in ovarian aging: a review ENSG00000002330 ENSG00000181019 ENSG00000198793 ENSG00000079999 PMC5381329__F1 Homocysteine metabolic pathway ENSG00000116761 ENSG00000116984 PMC3548977__F1 Itraconazole and arsenic trioxide inhibit hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists ENSG00000164161 ENSG00000136997 ENSG00000171791 ENSG00000128602 PMC8204050__F7 Key Macrophage Responses to Infection With Mycobacterium tuberculosis Are Co-Regulated by microRNAs and DNA Methylation ENSG00000180210 ENSG00000135218 ENSG00000179091 ENSG00000001626 ENSG00000096717 ENSG00000164087 ENSG00000026103 PMC9457687__F5 Single cell states of the NFKB signaling pathway ENSG00000125538 ENSG00000169429 ENSG00000166278 PMC2235216__F1 Arsenic-induced acquired androgen independence ENSG00000177606 PMC8074247__F6 Analysis of LAGEs Family Gene Signature and Prognostic Relevance in Breast Cancer ENSG00000149311 ENSG00000175054 ENSG00000134982 ENSG00000163914 ENSG00000173599 ENSG00000136826 PMC8074247__F4 Analysis of LAGEs Family Gene Signature and Prognostic Relevance in Breast Cancer ENSG00000142192 ENSG00000183625 ENSG00000111837 ENSG00000168803 PMC10135714__F10 Schematic illustration shows the protective effect of extract of Lonicera japonica in particulate-matter (PM)2 ENSG00000172936 PMC8074247__F8 Analysis of LAGEs Family Gene Signature and Prognostic Relevance in Breast Cancer ENSG00000149311 ENSG00000140992 ENSG00000175054 ENSG00000158636 ENSG00000123374 ENSG00000127948 ENSG00000062485 PMC8783446__F10 Novel Gamma-sarcoglycan interactors in murine muscle membranes ENSG00000157764 ENSG00000197471 ENSG00000176393 ENSG00000173402 ENSG00000111678 ENSG00000170624 ENSG00000111077 ENSG00000185053 ENSG00000127990 ENSG00000128050 ENSG00000102683 ENSG00000196531 ENSG00000138162 ENSG00000100439 ENSG00000185129 ENSG00000121060 ENSG00000198947 PMC6274615__F1 KEGG-defined p53 signaling pathway with dysregulated mRNA and miRNA highlighted ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000002330 ENSG00000136997 ENSG00000123374 ENSG00000112378 PMC8465847__F1 Potential of Tissue-Resident Memory T Cells for Adoptive Immunotherapy against Cancer ENSG00000168329 ENSG00000089692 ENSG00000020633 ENSG00000198846 ENSG00000180644 PMC6408950__F1 RBP-J functions as a key negative regulator of osteoclastogenesis and inflammatory bone resorption ENSG00000197943 ENSG00000131196 PMC2924379__F2 Examination of Apoptosis Signaling in Pancreatic Cancer by Computational Signal Transduction Analysis ENSG00000100290 ENSG00000002330 ENSG00000102871 ENSG00000168040 ENSG00000175104 ENSG00000135116 ENSG00000064012 ENSG00000164305 ENSG00000115317 ENSG00000276068 PMC11842356__F2 Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics ENSG00000169245 ENSG00000183735 ENSG00000164430 PMC8481092__F1 MiR-2392 in driving SARS-CoV-2 infection ENSG00000142192 ENSG00000163914 ENSG00000114268 PMC2920679__F1 Regulation of mammalian target of rapamycin (mTOR) signaling functions ENSG00000109670 PMC5035594__F1 Anticipatory UPR Activation: A Protective Pathway and Target in Cancer ENSG00000144895 ENSG00000284161 ENSG00000167658 PMC5035594__F2 Anticipatory UPR Activation: A Protective Pathway and Target in Cancer ENSG00000019991 ENSG00000291971 ENSG00000138798 ENSG00000186716 PMC2709429__F11 Production of Superoxide Anions by Keratinocytes Initiates P. acnes-Induced Inflammation of the Skin ENSG00000135218 PMC11880921__F1 Biosynthesis pathway of GD2 (5) ENSG00000069482 ENSG00000135454 ENSG00000111728 ENSG00000158470 ENSG00000148154 PMC3272624__F1 Schematic depicting mTORC1 signaling in a NAC a medium spiny neuron with anterogradely transported BDNF being released from a VTA dopamine neuron terminal and glutamate released from a prefrontal cortex projection neuron ENSG00000198793 PMC6352924__F2 Tumour necrosis factor receptor 1 (TNFR1) signalling pathway ENSG00000137275 ENSG00000102871 ENSG00000082512 ENSG00000157625 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC7642974__F1 Action and classification of E3 ubiquitin ligases causing neurological diseases in human ENSG00000197579 ENSG00000119401 ENSG00000154582 ENSG00000113851 ENSG00000153827 ENSG00000008853 ENSG00000100225 ENSG00000103657 ENSG00000101871 ENSG00000078747 ENSG00000113558 ENSG00000183580 ENSG00000138411 ENSG00000153201 ENSG00000109654 ENSG00000157911 ENSG00000072803 ENSG00000086758 ENSG00000101695 ENSG00000280616 ENSG00000120925 ENSG00000163961 ENSG00000158290 ENSG00000100387 ENSG00000167986 ENSG00000085382 ENSG00000131323 ENSG00000103264 ENSG00000151148 ENSG00000148356 PMC5830185__F2 Current evidence on statin use and prostate cancer prevention: are we there yet? ENSG00000138798 ENSG00000198793 ENSG00000163914 ENSG00000123374 PMC5840201__F1 Neurosteroid synthesis in the retina ENSG00000036530 ENSG00000135929 PMC5543040__F1 Gonadotropin-releasing hormone (GnRH) receptor signal transduction in human cancers ENSG00000012048 ENSG00000109163 ENSG00000291971 ENSG00000130522 ENSG00000138798 ENSG00000146648 PMC2865534__F1 Heterologous Expression and Maturation of an NADP-Dependent [NiFe]-Hydrogenase: A Key Enzyme in Biofuel Production ENSG00000158104 PMC2814769__F5 Primary Cilium as a Complex Signaling Center ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4148120__F7 MAPK pathway as an apoptosis enhancer in melanoma ENSG00000157764 ENSG00000166068 PMC5006112__F1 MTOR pathway ENSG00000198793 ENSG00000164327 ENSG00000146648 PMC5817802__F3 Model for TMPRSS2-ERG regulation of the IGF1R gene ENSG00000157554 PMC7525950__F2 PI3K-mTOR autophagy pathway utilizes PIP3 lipid signaling ENSG00000177169 PMC7007879__F7 Potential differences between Socs3 and Cish gene expression ENSG00000114737 PMC2861325__F9 An Ingenuity pathway analysis containing about half of the genes in subfactor 8 of Myc factor 6 ENSG00000167553 ENSG00000131462 ENSG00000178999 ENSG00000147604 ENSG00000087586 ENSG00000117707 ENSG00000108829 ENSG00000117650 ENSG00000156970 ENSG00000141480 ENSG00000143761 ENSG00000175166 ENSG00000136997 ENSG00000112182 ENSG00000108671 ENSG00000149554 ENSG00000112742 ENSG00000108106 ENSG00000108433 PMC6387281__F1 Schematic overview of the autophagy process and genetic and drug targets to inhibit specific aspects of autophagy ENSG00000152348 ENSG00000083290 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC8557683__F6 Circular RNA expression profiles in human bronchial epithelial cells treated with beryllium sulfate ENSG00000213928 ENSG00000002330 ENSG00000154016 PMC1890551__F1 Eumelanin synthesis pathway and gene duplications in vertebrates ENSG00000104044 ENSG00000080166 ENSG00000107165 PMC1550314__F1 Ras activation in response to phorbol ester proceeds independently of the EGFR via an unconventional nucleotide-exchange factor system in COS-7 cells ENSG00000113070 ENSG00000146648 PMC7261339__F1 RhoA/ROCK signalling pathway in PH pathogenesis ENSG00000170365 ENSG00000135446 ENSG00000123374 PMC1890551__F4 Pteridine synthesis pathway and gene duplications in vertebrates ENSG00000150787 ENSG00000137880 ENSG00000116096 ENSG00000158125 PMC7935738__F1 Hepatic bile acid metabolism ENSG00000160867 ENSG00000167910 ENSG00000135929 PMC5969560__F1 Mitochondrial complex III Rieske Fe-S protein processing and assembly ENSG00000169021 ENSG00000182511 ENSG00000011295 ENSG00000140740 ENSG00000179091 ENSG00000156467 ENSG00000010256 PMC3586680__F1 Schematic diagrams of WWOX structure and its role in signaling ENSG00000291971 ENSG00000134982 ENSG00000178568 PMC7325873__F2 Graphical representation of DENV life cycle and subversion of the innate immune response: The virus enters the host cell through receptor mediated endocytosis or antibody dependent enhancement ENSG00000140564 ENSG00000088888 ENSG00000115415 ENSG00000136869 ENSG00000164342 PMC3235041__F1 SULT1A1, CYP2C19 and disease-free survival in early breast cancer patients receiving tamoxifen ENSG00000196502 ENSG00000165841 ENSG00000197408 ENSG00000140505 PMC5653458__F1 Emerging roles for the lysosome in lipid metabolism ENSG00000130164 ENSG00000107798 ENSG00000119655 ENSG00000141458 ENSG00000075239 PMC4403552__F1 Fabric of signaling cascades can be activated by astrocyte Gq-GPCRs ENSG00000065357 ENSG00000070831 PMC4658486__F4 Pathophysiology and management of CVD ENSG00000039537 ENSG00000166278 ENSG00000162692 PMC4104073__F2 Splicing regulation of the androgen receptor (AR) and phosphoinositide 3-kinase (PI3K) signaling pathways ENSG00000066468 ENSG00000136997 PMC8448888__F5 Suggested scheme of the SNO-dependent mTOR activation in the ASD and AD mouse models ENSG00000162889 ENSG00000145979 ENSG00000155792 ENSG00000167965 ENSG00000175104 PMC8231932__F4 Functions of Coronavirus Accessory Proteins: Overview of the State of the Art ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000171791 ENSG00000168040 ENSG00000026103 PMC2268988__F3 Life and death decisions by the E2F transcription factors ENSG00000002330 ENSG00000120868 ENSG00000096717 PMC8448888__F3 Clustering analysis of the SNOed proteins in ASD and AD mouse models ENSG00000142192 ENSG00000107282 ENSG00000105171 ENSG00000145920 ENSG00000087460 PMC10379139__F2 Genetic Risk Factors Related to Coronary Artery Disease and Role of Transforming Growth Factor Beta 1 Polymorphisms ENSG00000105329 PMC8815029__F1 Mechanical Stimulation on Mesenchymal Stem Cells and Surrounding Microenvironments in Bone Regeneration: Regulations and Applications ENSG00000103335 PMC9456274__F1 Ceramide Acyl Chain Length and Its Relevance to Intracellular Lipid Regulation ENSG00000139624 ENSG00000154227 ENSG00000147869 PMC8231932__F2 Functions of Coronavirus Accessory Proteins: Overview of the State of the Art ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000131323 PMC8231932__F3 Functions of Coronavirus Accessory Proteins: Overview of the State of the Art ENSG00000162711 ENSG00000131323 PMC3600733__F2 The quantitative system pharmacology approach for a schizophrenia model is based on actual preclinical neurophysiology and human neuroanatomy ENSG00000128052 PMC8191213__F3 Overexpression of DDIT4 and TPTEP1 are associated with metastasis and advanced stages in colorectal cancer patients: a study utilizing bioinformatics prediction and experimental validation ENSG00000058085 ENSG00000163032 ENSG00000119953 ENSG00000137573 PMC6572052__F3 Transforming growth factorB (TGFB) signaling pathway with marked expression levels of deregulated genes ENSG00000067141 ENSG00000049323 ENSG00000111537 ENSG00000095739 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000185591 ENSG00000164093 PMC6572052__F4 Hippo Signaling pathway with marked expression levels of deregulated genes ENSG00000139330 ENSG00000159921 ENSG00000126016 ENSG00000109321 ENSG00000134982 ENSG00000081051 ENSG00000132849 ENSG00000169435 ENSG00000116962 PMC6281221__F5 Analysis of the transcriptome data in Litopenaeus vannamei reveals the immune basis and predicts the hub regulation-genes in response to high-pH stress ENSG00000104899 ENSG00000159224 ENSG00000002330 ENSG00000138622 ENSG00000146469 ENSG00000198626 ENSG00000157017 ENSG00000099822 ENSG00000106571 ENSG00000125398 ENSG00000156299 ENSG00000149269 ENSG00000163914 ENSG00000177606 ENSG00000001626 ENSG00000160293 PMC9081902__F2 Processing of dietary lipids for chylomicrons synthesis ENSG00000135218 ENSG00000042832 ENSG00000110244 ENSG00000138823 ENSG00000186063 ENSG00000170456 ENSG00000198670 PMC6539587__F1 Sequence information of the overexpression vector HIF-1Alpha-pcDNA3.0 PMC9006750__F1 Pathway choice in replication-coupled ICL repair ENSG00000109674 ENSG00000183763 ENSG00000187790 ENSG00000165280 PMC6816781__F6 Signaling pathway regarding the cell cycle regulation in human bladder transitional carcinoma/BFTC-905 cells after stimulated by LSS ENSG00000170365 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000145386 PMC11822028__F3 Transcriptomic and proteomic profiles of G. subvermispora and T. versicolor of 4-HBA catabolic pathways, TCA cycle, and glyoxylate shunt under different cultivation conditions ENSG00000062485 PMC7910522__F3 Retinoids in the visual cycle: role of the retinal G protein-coupled receptor ENSG00000135437 ENSG00000121207 ENSG00000116745 ENSG00000197713 ENSG00000080511 PMC9163413__F8 Anti-Influenza Effect and Mechanisms of Lentinan in an ICR Mouse Model ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC3266783__F2 Basal cell carcinoma — molecular biology and potential new therapies ENSG00000180447 ENSG00000164161 ENSG00000144857 ENSG00000166813 ENSG00000121067 ENSG00000128602 PMC2749259__F2 Hypothetical diagram of possible sites of action of non-opioids in the regulatory pathway of IL-6 ENSG00000115415 ENSG00000168610 PMC5500325__F7 Nutritional and reproductive signaling revealed by comparative gene expression analysis in Chrysopa pallens (Rambur) at different nutritional statuses ENSG00000002330 ENSG00000198793 ENSG00000026103 PMC9047912__F1 Genetic Polymorphisms in microRNA Genes Targeting PI3K/Akt Signal Pathway Modulate Cervical Cancer Susceptibility in a Chinese Population ENSG00000110395 ENSG00000269335 ENSG00000171791 ENSG00000099942 ENSG00000175104 PMC3693156__F1 Cholesterol synthesis pathway ENSG00000070831 PMC3705986__F7 Schematic diagram that describes neuroprotective effects of SUL against ABeta-induced oxidative cell death in AD ENSG00000181019 ENSG00000062485 ENSG00000079999 PMC11760869__F1 Role of the IHH/PTHrP signaling pathway in regulating chondrocyte hypertrophy ENSG00000128602 ENSG00000163501 PMC6260216__F8 Scheme summarizing the protective effects of miR-27a on LPS-induced acute lung injury via the inhibiting TLR4/MyD88/NFKB activation ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC9582513__F3 DNA damage checkpoint execution and the rules of its disengagement ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000138346 ENSG00000197299 ENSG00000139618 PMC8774043__F7 Extracellular HSP90A Induces MyD88-IRAK Complex-Associated IKKA/B−NFKB/IRF3 and JAK2/TYK2−STAT-3 Signaling in Macrophages for Tumor-Promoting M2-Polarization ENSG00000177575 ENSG00000265808 ENSG00000105397 ENSG00000172936 ENSG00000136869 ENSG00000168610 ENSG00000184216 PMC10891274__F2 YAP/TAZ in fibroblast-like synovial cells (FLS) and its related signaling pathway involved in RA ENSG00000197905 ENSG00000007866 ENSG00000074219 PMC11760869__F2 Roles of the WNT, BMP, and TGFB signaling pathways in regulating chondrocyte hypertrophy ENSG00000170365 ENSG00000281324 ENSG00000125398 ENSG00000162337 ENSG00000134982 ENSG00000157766 ENSG00000168036 PMC11760869__F3 Roles of the hypoxia, inflammatory (NFKB and VEGF), FGF, YAP, and mTOR signaling pathways in regulating chondrocyte hypertrophy ENSG00000198793 PMC3360882__F8 Tetraspanin CD37 Directly Mediates Transduction of Survival and Apoptotic Signals ENSG00000104894 ENSG00000168036 PMC5216724__F6 EGR1 mediates miR-203a suppress the hepatocellular carcinoma cells progression by targeting HOXD3 through EGFR signaling pathway ENSG00000128652 ENSG00000146648 PMC6149728__F1 Schematic model for IL-1 mediated induction of IL-22 in cancer ENSG00000162711 ENSG00000125538 ENSG00000106546 PMC6944604__F5 The roles of ADAR2-mediated RNA editing in cancer development ENSG00000146477 ENSG00000163453 PMC4085722__F2 Regulation of protein trafficking, receptor signaling, and protein clearance by ubiquitination in Alzheimer's disease ENSG00000142192 ENSG00000134057 ENSG00000134982 ENSG00000116661 ENSG00000109670 PMC6048292__F1 Ferroptosis and its molecular regulation by Nrf2 ENSG00000167468 PMC10933339__F9 Schematic model of the contributor and potential mechanism of KAL in the occurrence and development of NAFLD ENSG00000281324 ENSG00000011198 ENSG00000177666 ENSG00000136826 PMC10891274__F1 YAP/TAZ activity is tightly regulated via Hippo signaling ENSG00000197905 ENSG00000114978 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 ENSG00000101425 PMC5142168__F11 Inhibition of HCO3− absorption by HMGB1 in the MTAL ENSG00000163914 ENSG00000189403 ENSG00000067900 PMC6944604__F2 The roles of ADAR1-mediated RNA editing in Multiple myeloma (MM), basal cell carcinoma (BCC) and medulloblastoma (MB) ENSG00000157540 ENSG00000140398 PMC2171390__F7 Calcium-independent microtubule-dependent pathway is required for FcɛRI-mediated degranulation in mast cells ENSG00000033327 ENSG00000010810 PMC10383295__F2 High levels of ROS promote cancer cell growth, proliferation, invasion, and metastasis ENSG00000138385 PMC10383295__F3 Cancer Metabolism: The Role of ROS in DNA Damage and Induction of Apoptosis in Cancer Cells ENSG00000012048 ENSG00000002330 ENSG00000102871 ENSG00000198793 ENSG00000168040 PMC8000459__F3 GP6 Signaling Pathway in HS line of Japanese quail ENSG00000213658 ENSG00000278316 ENSG00000151967 ENSG00000010671 PMC7047328__F2 Tryptophan breakdown via the kynurenine pathway and its interactions with the immune system: This figure illustrates tryptophan breakdown via the kynurenine pathway ENSG00000015285 ENSG00000188676 ENSG00000106546 PMC5322732__F6 Summary and pathway schematic ENSG00000121989 ENSG00000163939 ENSG00000198793 ENSG00000095015 ENSG00000099860 ENSG00000129514 ENSG00000049618 ENSG00000079432 ENSG00000169032 ENSG00000121879 ENSG00000166068 ENSG00000124762 ENSG00000117713 ENSG00000186575 ENSG00000136997 ENSG00000156531 ENSG00000105810 ENSG00000048028 ENSG00000139687 ENSG00000215301 ENSG00000196712 ENSG00000177425 ENSG00000157764 ENSG00000078369 ENSG00000065559 ENSG00000126012 ENSG00000079999 ENSG00000149311 ENSG00000135446 ENSG00000177606 ENSG00000060339 ENSG00000158545 ENSG00000146648 ENSG00000171533 ENSG00000189079 PMC7539315__F5 Transcriptome Changes in Colorectal Cancer Cells upon Treatment with Avicequinone B ENSG00000111684 ENSG00000131095 ENSG00000115107 PMC7796775__F1 Steroidogenesis pathway in 21-hydroxylase deficiency ENSG00000203859 ENSG00000179142 ENSG00000176387 PMC6700212__F1 Dual sequential cell death checkpoints in the TNFR1 signaling pathway ENSG00000137275 ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC8350018__F3 Bisphenol A-induced DNA damages promote to lymphoma progression in human lymphoblastoid cells through aberrant CTNNB1 signaling pathway ENSG00000109320 ENSG00000168036 PMC9561420__F2 Microbial dysbiosis and childhood asthma development: Integrated role of the airway and gut microbiome, environmental exposures, and host metabolic and immune response ENSG00000183735 ENSG00000136869 ENSG00000175104 PMC321431__F10 Cascade of transcription factors that induce stress gene expression in response to eIF2A phosphorylation ENSG00000128272 ENSG00000162772 PMC6507454__F5 Transcriptome analysis results of nuclear factor erythroid-2 related factor 2 knockdown ENSG00000181472 ENSG00000125740 ENSG00000130522 ENSG00000099860 ENSG00000168036 ENSG00000175592 ENSG00000088038 ENSG00000089159 ENSG00000150782 ENSG00000125538 ENSG00000090615 ENSG00000092067 ENSG00000196498 ENSG00000101197 ENSG00000188612 ENSG00000183479 ENSG00000142655 ENSG00000125826 ENSG00000185022 ENSG00000116329 ENSG00000173786 ENSG00000107447 ENSG00000164985 ENSG00000073921 ENSG00000198517 ENSG00000152465 ENSG00000121864 ENSG00000165462 ENSG00000087274 PMC7761500__F2 Various tumor-promoting mechanisms that can be exploited in combination with immune checkpoint inhibition ENSG00000163464 ENSG00000111537 ENSG00000122691 ENSG00000105656 ENSG00000168610 PMC7609165__F1 Host-Pathogen Dialogues in Autophagy, Apoptosis, and Necrosis during Mycobacterial Infection ENSG00000123576 ENSG00000164430 ENSG00000166523 ENSG00000198793 ENSG00000112561 ENSG00000172936 ENSG00000136869 ENSG00000237693 ENSG00000221926 PMC6402819__F5 R-loops drive DNA damage responses ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000138385 PMC9511979__F1 Relationships among microbiota, gastric cancer, and immunotherapy ENSG00000168036 ENSG00000164690 PMC9511979__F2 Relationships among microbiota, gastric cancer, and immunotherapy ENSG00000033178 ENSG00000111537 ENSG00000134982 ENSG00000163599 ENSG00000145321 PMC7037737__F5 Interactions between the WNT pathway and aerobic glycolysis in exudative AMD ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11216096__F2 Wnt signaling in gastric cancer: current progress and future prospects ENSG00000162552 ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000169884 ENSG00000185483 ENSG00000168036 ENSG00000277641 ENSG00000125084 ENSG00000196628 ENSG00000108375 ENSG00000134245 PMC11216096__F1 Wnt signaling in gastric cancer: current progress and future prospects ENSG00000134982 ENSG00000168036 ENSG00000132478 PMC9408922__F1 Biochemical Hazards during Three Phases of Assisted Reproductive Technology: Repercussions Associated with Epigenesis and Imprinting ENSG00000228716 ENSG00000173638 PMC9696608__F1 Immunotherapeutic Implications of Toll-like Receptors Activation in Tumor Microenvironment ENSG00000172936 ENSG00000131323 ENSG00000164342 PMC2804071__F4 Joubert syndrome: insights into brain development, cilium biology and complex disease ENSG00000103494 ENSG00000140463 ENSG00000138795 ENSG00000156313 ENSG00000169379 ENSG00000134853 ENSG00000168036 ENSG00000164690 ENSG00000174483 ENSG00000144061 ENSG00000048342 PMC8602690__F2 Mechanism Actions of Astragaloside IV Prevents the Progression of Hypertensive Heart Disease Based on Network Pharmacology and Experimental Pharmacology ENSG00000173039 ENSG00000213341 ENSG00000112715 ENSG00000005381 PMC3585156__F5 Net Expression Inhibits the Growth of Pancreatic Ductal Adenocarcinoma Cell PL45 In Vitro and In Vivo ENSG00000135446 ENSG00000123374 PMC11119514__F1 RDNVs reverse osteoporosis by potentiating osteogenic differentiation of hBMSCs via targeting estrogen receptor A (ERA) signaling ENSG00000170365 PMC5061806__F2 Targeting mTOR for neurodegenerative disorders ENSG00000138798 ENSG00000198793 ENSG00000096717 PMC8780245__F7 Dendritic cell-mediated chronic low-grade inflammation is regulated by the RAGE-TLR4-PKCB1 signaling pathway in diabetic atherosclerosis ENSG00000173039 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC8496745__F1 How Oncogenic Viruses Exploit p62-Mediated Selective Autophagy for Cancer Development ENSG00000012048 ENSG00000177169 ENSG00000183735 ENSG00000163961 ENSG00000164430 ENSG00000113595 ENSG00000051180 ENSG00000079999 PMC1681476__F1 An SBGN process diagram (A) and a molecular interaction map (B) of a signaling pathway triggered by ligand binding to EGFR molecules ENSG00000169291 ENSG00000138798 ENSG00000146648 PMC4139479__F6 A Novel Mechanism of Skin Tumor Promotion Involving Interferon-gamma (IFNG)/Signal Transducer and Activator of Transcription-1 (Stat1) Signaling ENSG00000111537 ENSG00000027697 PMC5819891__F4 Homeostatic Systems, Biocybernetics, and Autonomic Neuroscience ENSG00000084093 ENSG00000197471 PMC8151764__F1 Recent Research Progress in Taxol Biosynthetic Pathway and Acylation Reactions Mediated by Taxus Acyltransferases ENSG00000197429 PMC8591697__F2 Targeting regulatory T cells for immunotherapy in melanoma ENSG00000177575 ENSG00000089692 PMC2417166__F8 Wnt signaling pathways in INS-1 cells ENSG00000138798 ENSG00000168036 PMC6114982__F8 Palbociclib resistance and MAP kinase pathway inhibition ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 ENSG00000277273 PMC11687129__F8 Mechanism of TAL in PD models ENSG00000174417 ENSG00000170893 ENSG00000149295 PMC7606110__F1 Current regulatory model of Wnt/Beta-catenin signaling, and the Wnt-targeting natural compounds which are currently under investigation ENSG00000134982 ENSG00000026508 ENSG00000168036 PMC2423294__F8 The PKD1/class II HDAC/MEF2 signaling pathway in skeletal muscle ENSG00000008710 PMC8786725__F1 Distribution and Effects of Estrogen Receptors in Prostate Cancer: Associated Molecular Mechanisms ENSG00000074410 PMC8326751__F4 Combination of a Novel Genetic Variant in CFB Gene and a Pathogenic Variant in COL4A5 Gene in a Sibling Renal Disease: A Case Report ENSG00000288512 ENSG00000182326 PMC5068240__F10 Model illustrating the mode of action of RLTPR in T cells PMC9035706__F1 Multienzyme interactions of the de novo purine biosynthetic protein PAICS facilitate purinosome formation and metabolic channeling ENSG00000284320 ENSG00000128050 ENSG00000065911 ENSG00000100714 ENSG00000120254 PMC11040302__F1 Application of artificial hibernation technology in acute brain injury ENSG00000177575 ENSG00000102317 ENSG00000172936 ENSG00000136869 PMC8437760__F2 Induced pluripotent stem cell-based disease modeling and prospective immune therapy for coronavirus disease 2019 ENSG00000291363 ENSG00000171476 ENSG00000164736 ENSG00000125398 ENSG00000161798 ENSG00000138798 ENSG00000174059 ENSG00000281857 PMC5338303__F2 Schemes of kinetic model used as a base for simulation of isotopologue distribution ENSG00000122966 ENSG00000173599 ENSG00000172005 PMC9521683__F2 The POMC System on Glucose Homeostasis and Potential Therapeutic Targets for Obesity and Diabetes ENSG00000171105 ENSG00000150907 ENSG00000198576 ENSG00000072315 ENSG00000124181 ENSG00000168610 PMC6462321__F7 General summary of the NBP-involved cellular signal pathway in (a) cancer cell proliferation, migration, and apoptosis and in (b) stem cell differentiation ENSG00000171791 ENSG00000100985 PMC3227667__F3 Genetic Signature of Spina Bifida Risk from Pathway-Informed Comprehensive Gene-Variant Analysis ENSG00000284320 ENSG00000228716 ENSG00000065911 ENSG00000100714 ENSG00000103707 ENSG00000145020 ENSG00000120254 PMC4700477__F10 Selected potential Rho GTPase functional networks identified in the RNAi screen ENSG00000038382 ENSG00000116641 ENSG00000102606 ENSG00000114346 ENSG00000070831 ENSG00000055163 ENSG00000163914 ENSG00000100852 ENSG00000288461 ENSG00000088387 PMC6121505__F2 Inhibition of apoptosis mediated by mFas and TRAIL ENSG00000124102 ENSG00000138798 ENSG00000168040 PMC6121505__F3 Role of TLR3, 7 and 9 in SS ENSG00000183735 ENSG00000239732 ENSG00000138798 ENSG00000172936 ENSG00000168040 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC10610100__F2 Protein–protein interaction (PPI) network map of the KEGG enriched signal pathway of differential genes ENSG00000211445 ENSG00000169220 ENSG00000164161 ENSG00000146469 ENSG00000116741 ENSG00000152402 ENSG00000043462 PMC6691693__F2 Differentially expressed genes involved in cell cycle pathway ENSG00000108055 ENSG00000205250 ENSG00000091651 ENSG00000277273 ENSG00000117399 ENSG00000276876 ENSG00000093009 ENSG00000145604 ENSG00000135446 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000105810 PMC5351557__F2 Yeast mitogen-activated protein kinase signaling pathway, illustrating the signaling paths in responses to different signals ENSG00000111837 ENSG00000197601 PMC6859786__F1 NLR-dependent regulation of MHC class I antigen presentation ENSG00000162711 ENSG00000167207 ENSG00000125538 ENSG00000273686 ENSG00000106100 PMC11877141__F0 Battling pain from osteoarthritis: causing novel cell death ENSG00000278718 ENSG00000162711 ENSG00000102871 ENSG00000198793 ENSG00000168036 ENSG00000265972 ENSG00000137845 ENSG00000104332 ENSG00000164430 ENSG00000181019 ENSG00000136997 ENSG00000168404 ENSG00000115107 ENSG00000104321 ENSG00000253506 ENSG00000137275 ENSG00000086991 ENSG00000168040 ENSG00000170425 ENSG00000127191 ENSG00000079999 ENSG00000167468 ENSG00000172936 ENSG00000096717 ENSG00000285379 ENSG00000103335 PMC9705310__F8 Schematic diagram of the proposed divergent effects of astrocyte-specific Cp knockout on learning and memory function PMC11956203__F4 Key mechanisms of neuro-cancer crosstalk in HNC ENSG00000087245 ENSG00000182687 ENSG00000137673 ENSG00000196154 ENSG00000100985 ENSG00000118777 ENSG00000121966 PMC7085407__F3 PGC-1A signaling pathway in response to ROS/RNS ENSG00000284194 ENSG00000142082 PMC6682711__F2 Autophagy signaling in HCC ENSG00000177169 ENSG00000168036 PMC8711784__F2 Regulatory Network of Cyclic GMP-AMP Synthase-Stimulator of Interferon Genes Pathway in Viral Evasion ENSG00000183735 ENSG00000164430 PMC2887331__F2 Serine/threonine kinase Akt, also known as protein kinase B (PKB), has become a major focus of attention because of its critical regulatory role in diverse cellular processes, including cancer progression ENSG00000002330 ENSG00000198793 PMC7155254__F4 ERS and oxidative stress in patients with NAFLD and the generation and crosstalk of ROS signalling connecting these pathways ENSG00000128272 ENSG00000169047 ENSG00000130649 ENSG00000100219 ENSG00000120868 ENSG00000171791 ENSG00000127191 PMC8711784__F1 Regulatory Network of Cyclic GMP-AMP Synthase-Stimulator of Interferon Genes Pathway in Viral Evasion ENSG00000183735 ENSG00000213928 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC6929077__F1 Nicotinamide (NAM) and Nicotinamide Adenine Dinucleotide (NAD+) metabolism ENSG00000105835 ENSG00000123572 ENSG00000278488 ENSG00000008130 PMC2921957__F4 Summary of factor H recognition functions and interactions ENSG00000132693 PMC11854763__F2 Signaling pathways directly and indirectly linked to RhoA/ROCK-mediated activation of GSK3B and the positive feedback loop between AB deposition and GSK3B activation ENSG00000142192 ENSG00000281324 ENSG00000291971 ENSG00000067900 PMC8666288__F2 Cellular stress response to extremely low‐frequency electromagnetic fields (ELF‐EMF): An explanation for controversial effects of ELF‐EMF on apoptosis ENSG00000128272 ENSG00000198793 ENSG00000132478 PMC7906326__F3 Current understanding of the interplays between host hormones and plant viral infections ENSG00000092847 PMC9200435__F3 Metabolic reprogramming in pancreatic adenocarcinoma (PDAC) ENSG00000057252 ENSG00000131473 ENSG00000065833 ENSG00000130164 ENSG00000113161 ENSG00000103257 PMC2857099__F6 Proposed model for NFKB repression by TRAF3 in LTBR activation ENSG00000111321 ENSG00000131323 ENSG00000127191 PMC6002979__F1 B cell receptor signaling pathway ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000198793 ENSG00000175104 ENSG00000010671 ENSG00000198286 PMC3281723__F2 Role of PHLPP in terminating oncogenic signaling pathways ENSG00000198793 PMC6002979__F2 Canonical and non-canonical NFKB signaling pathways ENSG00000104856 ENSG00000226275 ENSG00000198793 ENSG00000136869 ENSG00000175104 PMC8971810__F4 C1q/Tumor Necrosis Factor-Related Protein 9: Basics and Therapeutic Potentials ENSG00000111537 ENSG00000170458 ENSG00000285109 ENSG00000170558 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000168610 PMC3807240__F1 The NLRP3 inflammasome regulates the DNA damage response pathway ENSG00000023445 PMC3161973__F1 Putative mogrosides biosynthesis pathway in Siraitia grosvenorii ENSG00000167508 ENSG00000062485 PMC7712090__F2 Analysis of miRNA Expression in Patients with Rheumatoid Arthritis during Olokizumab Treatment ENSG00000177606 ENSG00000115904 ENSG00000101266 ENSG00000169032 ENSG00000168610 ENSG00000179295 PMC7500866__F1 Somatic Liver Knockout (SLiK): A quick and efficient way of generating liver-specific knockout mice using multiplex CRISPR/Cas9 gene editing ENSG00000065613 ENSG00000186603 ENSG00000158104 PMC3003974__F3 Protein interaction network of highly connected proteins associated with the cardiorenal syndrome ENSG00000051523 ENSG00000291971 ENSG00000138798 ENSG00000173039 ENSG00000116701 ENSG00000133216 ENSG00000132170 ENSG00000175054 ENSG00000172216 ENSG00000130234 ENSG00000136160 ENSG00000151617 ENSG00000171608 ENSG00000146648 ENSG00000100365 PMC4695871__F2 Binding of the Hedgehog ligand (SHH) to Patched (PTCH1) removes the inhibitory signal for the G-protein-coupled receptor, Smoothened (SMO), causing translocation of the GLI1 and GLI2 transcription factors into the nucleus ENSG00000164690 ENSG00000128602 PMC8016706__F2 Growth and stress signalling pathways dictate responsiveness to stimuli and are hijacked in skin malignancy ENSG00000104856 ENSG00000100234 ENSG00000162552 ENSG00000135960 ENSG00000138798 ENSG00000136997 ENSG00000173039 ENSG00000171791 ENSG00000114315 ENSG00000146648 PMC7415804__F1 Canonical Type I IFN signaling activated by DNA virus and RNA virus ENSG00000150455 ENSG00000127191 ENSG00000142166 ENSG00000183735 ENSG00000239732 ENSG00000111537 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000082512 ENSG00000172936 ENSG00000175104 ENSG00000121060 ENSG00000184216 ENSG00000164342 PMC9108753__F10 scEFSC: Accurate single-cell RNA-seq data analysis via ensemble consensus clustering based on multiple feature selections ENSG00000087095 ENSG00000134982 ENSG00000166090 ENSG00000122882 ENSG00000213658 ENSG00000095739 ENSG00000167941 ENSG00000111837 ENSG00000113558 ENSG00000198846 ENSG00000100211 ENSG00000127948 ENSG00000119125 PMC7415804__F2 Mechanisms of actions of lncRNAs in regulating innate antiviral response ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000121060 ENSG00000164342 ENSG00000142166 PMC5725130__F3 Identification of hub genes related to silicone-induced immune response in rats ENSG00000239732 ENSG00000170458 ENSG00000134982 ENSG00000186716 ENSG00000168040 ENSG00000150455 ENSG00000142224 ENSG00000062485 ENSG00000143387 PMC10232107__F2 Compound-gene targets-signaling pathway network of the eight phytochemicals related to neuroinflammation ENSG00000291971 ENSG00000164305 ENSG00000132170 PMC5768609__F1 Schematic diagram depicting the role of miR-27a in Mycobacterium avium subspecies paratuberculosis (MAP)-mediated signaling pathways in macrophage ENSG00000174125 ENSG00000125538 ENSG00000136869 PMC2910789__F1 Selected IGF-axis genes that encode core components of IGF-axis upstream the PI3K/AKT/mTOR and RAS/MAPK/ERK pathway ENSG00000169047 ENSG00000198793 ENSG00000146678 ENSG00000133124 ENSG00000115461 ENSG00000140443 PMC8050094__F6 Intracellular Ca2+ cycling ENSG00000198670 PMC6940904__F1 Overview of the complement cascade and principal complement targeting molecules ENSG00000039537 ENSG00000113600 ENSG00000197971 ENSG00000203710 ENSG00000236625 PMC8868096__F2 Role for Plant-Derived Antioxidants in Attenuating Cancer Cachexia ENSG00000181019 ENSG00000175793 ENSG00000079999 PMC3347452__F7 Proposed model of SubAB-induced PERK-mediated apoptosis signaling pathway in HeLa cells ENSG00000128272 ENSG00000144895 PMC3380363__F1 Oncogenic signaling pathways regulated by NO and PP2A ENSG00000291971 ENSG00000168036 ENSG00000146648 PMC3703147__F1 Ubiquitination-mediated regulation of interferon responses ENSG00000115415 PMC7752511__F1 Oxidative Stress, Nutrition and Cancer: Friends or Foes? ENSG00000178860 ENSG00000070193 ENSG00000105550 ENSG00000272398 ENSG00000174059 PMC8846937__F1 Pathophysiology of stress granules: An emerging link to diseases (Review) ENSG00000116001 PMC7549330__F7 Diagram illustrating the molecular mechanism of LINC01315 in proliferation, invasion, and migration of OSCC cells PMC6588869__F1 Monolignol and ethylene biosynthesis pathways ENSG00000165757 ENSG00000084774 PMC7560080__F3 ROS and low-molecular-weight hyaluronic acid (LMWHA) involvement in both priming and activation of the NLRP3 inflammasome ENSG00000162711 ENSG00000026508 ENSG00000172936 PMC8621356__F3 Targeting PI3K/Akt/mTOR Pathway by Different Flavonoids: A Cancer Chemopreventive Approach ENSG00000005882 ENSG00000169047 ENSG00000198793 PMC8621356__F2 Targeting PI3K/Akt/mTOR Pathway by Different Flavonoids: A Cancer Chemopreventive Approach ENSG00000002330 ENSG00000150907 ENSG00000198793 PMC10815772__F1 FGF/FGFR and downstream signaling pathway ENSG00000198793 PMC10815772__F2 Molecular Targeting of the Fibroblast Growth Factor Receptor Pathway across Various Cancers ENSG00000157404 ENSG00000198793 PMC5990418__F3A Getting the “kill” into “shock and kill”: strategies to eliminate latent HIV ENSG00000002330 ENSG00000150907 PMC4347898__F5 Phosphortlated Smad3 is stabilized by ERG in prostate cells ENSG00000157554 PMC7581496__F8 FGF18–FGFR2 signaling triggers the activation of c-Jun–YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential ENSG00000066468 ENSG00000070831 ENSG00000163914 ENSG00000156427 ENSG00000136997 ENSG00000150457 ENSG00000131023 PMC1236692__F3 Caspase signaling and its modulation ENSG00000148935 PMC12116916__F8 TLR4 signaling modes and outcomes ENSG00000183735 ENSG00000137275 ENSG00000172005 ENSG00000197943 ENSG00000172936 ENSG00000136869 PMC8044766__F1 Thrombotic and thrombolytic cascades and primordial immune response ENSG00000120742 ENSG00000110799 ENSG00000175899 ENSG00000122194 PMC7260648__F1 Mechanisms underlying cytoplasmic organellar dysfunction after chemotherapy and melatonin's protective effects under these conditions ENSG00000125538 ENSG00000142082 PMC6319725__F9 Transcriptomic characterization of signaling pathways associated with osteoblastic differentiation of MC-3T3E1 cells ENSG00000170365 ENSG00000105835 ENSG00000168040 PMC6319725__F8 Transcriptomic characterization of signaling pathways associated with osteoblastic differentiation of MC-3T3E1 cells ENSG00000100084 ENSG00000105835 ENSG00000160584 ENSG00000196839 ENSG00000132382 ENSG00000156427 ENSG00000185591 ENSG00000168040 PMC7539774__F6 Schematic diagram of HP-based regulation in breast cancer glycolytic signaling pathway ENSG00000067057 PMC10751872__F3 Advances in Regulating Cellular Behavior Using Micropatterns ENSG00000150457 ENSG00000131023 PMC3824073__F2 Outline of the Crosstalk between p53 Family Members and the mTORC1 Pathwayp53 and p63 act upstream of mTORC1 and inhibit mTORC1 activity via multiple transcriptional targets ENSG00000145632 PMC9266763__F2 Revisiting Regulated Cell Death Responses in Viral Infections ENSG00000278718 ENSG00000162711 ENSG00000150782 ENSG00000137275 ENSG00000189403 ENSG00000131323 ENSG00000083799 ENSG00000127191 ENSG00000285379 PMC9266763__F4 Revisiting Regulated Cell Death Responses in Viral Infections ENSG00000278718 ENSG00000105397 ENSG00000156575 ENSG00000008516 ENSG00000102871 ENSG00000130234 ENSG00000184012 ENSG00000091592 ENSG00000168040 ENSG00000168404 ENSG00000132693 ENSG00000285379 PMC4991322__F1 The conserved pathway of sterol synthesis, storage and transformation in C ENSG00000067064 ENSG00000074800 PMC9289199__F2 Hepatoprotective and Hepatotoxic Roles of Sex and Sex-Related Hormones ENSG00000130164 ENSG00000113161 ENSG00000160741 ENSG00000113494 PMC3891587__F2 GENETIC CONTROL OF CANDIDA ALBICANS BIOFILM DEVELOPMENT ENSG00000130234 ENSG00000117298 ENSG00000125450 ENSG00000100029 PMC2999593__F1 Heme Biosynthetic Pathway ENSG00000144410 ENSG00000126088 ENSG00000188690 PMC6192719__F5 Deduction of novel genes potentially involved in hypoxic AC16 human cardiomyocytes using next-generation sequencing and bioinformatics approaches ENSG00000158856 ENSG00000107745 ENSG00000011260 ENSG00000168036 ENSG00000196562 ENSG00000171791 ENSG00000171388 ENSG00000166401 ENSG00000159167 ENSG00000265808 ENSG00000196549 ENSG00000002549 ENSG00000118257 ENSG00000103264 ENSG00000163517 ENSG00000123689 ENSG00000141526 PMC8004672__F7 Correlation between growth factor signaling, the actin cytoskeleton, and CCN2 expression in CHs ENSG00000163235 PMC3766629__F6 Immunohistochemical Staining, Laser Capture Microdissection and FASP Assisted Proteomic Analysis of Target Cell Populations within Tissue Samples ENSG00000142798 ENSG00000070831 ENSG00000126247 ENSG00000178209 ENSG00000122786 ENSG00000120885 ENSG00000108821 ENSG00000117983 ENSG00000213024 ENSG00000236625 ENSG00000162896 PMC3823507__F1 Post-translational regulation of iron homeostasis ENSG00000010704 ENSG00000105697 ENSG00000115107 PMC5527460__F1 KRAS‐dependent genetic network analysis ENSG00000169594 ENSG00000143549 ENSG00000095059 ENSG00000105193 ENSG00000108960 ENSG00000124383 ENSG00000134759 ENSG00000176788 ENSG00000138386 ENSG00000163960 ENSG00000140807 ENSG00000062716 ENSG00000149311 ENSG00000012048 ENSG00000215021 ENSG00000150991 ENSG00000102034 ENSG00000115942 ENSG00000070950 ENSG00000051180 ENSG00000139726 PMC4075245__F1 Simplified schema showing how genes might affect clinical responses to targeted therapies ENSG00000138378 ENSG00000122223 ENSG00000163599 ENSG00000056558 ENSG00000280908 ENSG00000112486 PMC4657846__F6 Sites of complement pathway dysregulation ENSG00000000971 PMC3899800__F2 BRCA1 and its toolbox for the maintenance of genome integrity ENSG00000188486 ENSG00000163961 ENSG00000112130 PMC3899800__F3 BRCA1 and its toolbox for the maintenance of genome integrity ENSG00000144554 ENSG00000051180 PMC10531820__F6 Regulatory T Cells in Cancer Treatment Resistance ENSG00000198793 PMC6901085__F1 Representation of AKT pathway and downstream effectors ENSG00000033327 ENSG00000002330 ENSG00000198793 ENSG00000169047 ENSG00000164327 ENSG00000167965 ENSG00000186654 PMC8833603__F4 Protein Disulfide Isomerase in Breast Cancer ENSG00000128272 ENSG00000144895 PMC2577137__F1 Cross talk between PKA, PI3K/AKT and WNT/CTNNB1 intracellular signaling pathways ENSG00000150907 ENSG00000198793 ENSG00000168036 ENSG00000140443 PMC7843555__F1 Five domains of T-cell dysfunction ENSG00000100811 ENSG00000089692 ENSG00000181847 ENSG00000163599 ENSG00000026103 PMC2776679__F7 Egr-1 and Hipk2 are required for the TrkA to p75NTR switch that occurs downstream of IGF1-R ENSG00000064393 ENSG00000140443 PMC4657846__F1 Normal complement cascade ENSG00000039537 ENSG00000113600 ENSG00000288512 ENSG00000166278 ENSG00000182326 PMC4816186__F6 Notch 1 signaling pathway and proposed mechanism of action of CJ ENSG00000077150 ENSG00000197930 ENSG00000136997 ENSG00000137845 PMC9267699__F2 New Avenues of Heme Synthesis Regulation ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000256269 ENSG00000188690 PMC4657846__F2 Normal regulation of the complement AP ENSG00000000971 PMC4463661__F1 Biochemistry of hydrogen production in Synechocystis PCC 6803 by direct biophotolysis ENSG00000090402 ENSG00000173599 PMC5392381__F2 Central BCR signaling network constructed from literature ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000197943 ENSG00000010671 ENSG00000198286 PMC6473547__F5 Vitamins on Alzheimer’s disease ENSG00000137845 PMC6989314__F4 Pathway mechanism of the cell cycle ENSG00000145604 ENSG00000108055 ENSG00000132646 ENSG00000123374 ENSG00000277273 ENSG00000276876 PMC7057654__F2 Vaccinations can inhibit the release of various pro-tumor cytokines ENSG00000165527 PMC2600644__F4 Pathway schematic of significantly regulated genes in (A) NFKB signalling and (B) MAP kinase signalling ENSG00000070831 ENSG00000102871 ENSG00000056972 ENSG00000120889 ENSG00000168067 ENSG00000069956 ENSG00000139625 ENSG00000169967 ENSG00000186197 ENSG00000082512 ENSG00000056558 ENSG00000174125 ENSG00000104689 ENSG00000183763 ENSG00000100906 ENSG00000109320 ENSG00000291431 ENSG00000170425 ENSG00000127666 ENSG00000006062 ENSG00000076604 ENSG00000104814 ENSG00000138166 ENSG00000118503 ENSG00000177606 ENSG00000131323 ENSG00000049249 ENSG00000175104 ENSG00000204498 PMC3328839__F6 Proposed pathway ENSG00000167323 ENSG00000293604 ENSG00000198793 PMC7827439__F3 Cytokine-mediated immune–epithelial crosstalk in inflammatory bowel diseases ENSG00000099985 ENSG00000137033 ENSG00000134982 PMC5737637__F6 NAD(H) and NADP(H) Redox Couples and Cellular Energy Metabolism ENSG00000151376 ENSG00000065833 ENSG00000112992 PMC7327232__F4 Membrane receptors on parietal and enterochromaffin-like (ECL) cells and intracellular signaling pathways that regulate gastric acid secretion ENSG00000163235 ENSG00000138798 ENSG00000036828 ENSG00000146648 PMC5357762__F1 Canonical and non-canonical Wnt signaling ENSG00000063978 ENSG00000100592 ENSG00000134982 ENSG00000177606 ENSG00000058091 ENSG00000183579 ENSG00000168036 ENSG00000109670 PMC5737637__F2 NAD(H) and NADP(H) Redox Couples and Cellular Energy Metabolism ENSG00000105835 ENSG00000123572 ENSG00000278488 ENSG00000008130 PMC5357762__F2 Mutation rates of Wnt pathway components in selected cancer entities ENSG00000281324 ENSG00000134982 ENSG00000168036 ENSG00000108375 ENSG00000109670 PMC4910040__F1 mTOR signaling pathway ENSG00000163914 ENSG00000284161 ENSG00000167658 PMC6251962__F1 Innate immunity and adaptive immunity ENSG00000239732 ENSG00000137033 ENSG00000169429 ENSG00000145777 ENSG00000166090 PMC3943178__F3 Coordination of macrophage-mediated signaling and muscle regeneration ENSG00000111537 ENSG00000136826 PMC11016796__F2 Proteomic analyses on chicken breast meat with white striping myopathy ENSG00000158828 ENSG00000112208 ENSG00000124762 PMC5868586__F7 Schematic illustration of the underlying mechanism of L61H46’s anticancer activity.Abbreviations: IFN, interferon; IL, interleukin ENSG00000115415 ENSG00000168610 PMC3188673__F5 Vitamin D Metabolism and Function in the Skin ENSG00000134982 PMC8761221__F1 Autophagy regulatory pathways ENSG00000177169 ENSG00000083290 ENSG00000198793 ENSG00000164399 PMC2919366__F4 STAT3 signaling pathway ENSG00000111537 ENSG00000168610 PMC4224557__F8 Postulated molecular regulation of eukaryotic elongation factor-2 kinase (eEF-2K)/TG2 pathway to the invasion-promoting signalling in pancreatic cancer (PaCa) cells ENSG00000291971 PMC4600531__F1 Wnt Signaling in Bone and Muscle ENSG00000134982 PMC8422159__F12 Enhanced Expression of miR-34a Enhances Escherichia coli Lipopolysaccharide-Mediated Endometritis by Targeting LGR4 to Activate the NFKB Pathway ENSG00000172936 ENSG00000136869 PMC5234110__F7 Schematic representation of the suggested dynamic effects of PGE2 on naïve and primed microglia ENSG00000136869 PMC8141399__F1 Banxia Xiexin Decoction Inhibits the Expression of PD-L1 Through Multi-Target and Multi-Pathway Regulation of Major Oncogenes in Gastric Cancer ENSG00000111537 ENSG00000138798 ENSG00000198793 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000146648 PMC11616203__F3 Effect of TRPM channels on signal pathways related to tumor progression ENSG00000092439 ENSG00000132646 ENSG00000198793 ENSG00000168036 ENSG00000123374 ENSG00000134160 ENSG00000146648 PMC2171731__F9 Invadopodium formation ENSG00000070831 ENSG00000138798 PMC8242249__F6 Comparative Analysis of Coronavirus Nucleocapsid (N) Proteins Reveals the SADS-CoV N Protein Antagonizes IFNB Production by Inducing Ubiquitination of RIG-I ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000121060 ENSG00000101695 PMC7696523__F1 Canonical Hedgehog signaling in Basal Cell Carcinoma ENSG00000117425 ENSG00000128602 PMC12206634__F10 The diverse intestinal innate immune pathway responses induced by non-S INDEL and S INDEL PEDV strain in weaned (A) and suckling (B) piglets ENSG00000162711 ENSG00000088888 ENSG00000187608 ENSG00000183486 ENSG00000157601 ENSG00000160710 ENSG00000131323 ENSG00000127191 ENSG00000121060 ENSG00000276561 PMC7963165__F1 Upstream mediators of TXNIP signaling ENSG00000278718 ENSG00000162711 ENSG00000169136 ENSG00000172936 ENSG00000136869 ENSG00000265972 PMC5522257__F3 Distinct functions of dynamin isoforms in tumorigenesis and their potential as therapeutic targets in cancer ENSG00000197959 ENSG00000141968 PMC7757414__F1 Targeted therapies available and in development in Acute Myeloid Leukemia (AML) ENSG00000136807 ENSG00000122025 ENSG00000157404 ENSG00000183337 ENSG00000198793 ENSG00000171791 ENSG00000128602 ENSG00000184216 ENSG00000135605 ENSG00000121966 PMC8224798__F2 Harnessing the Physiological Functions of Cellular Prion Protein in the Kidneys: Applications for Treating Renal Diseases ENSG00000198793 PMC5355992__F9 Astragalus polysaccharides exerts immunomodulatory effects via TLR4-mediated MyD88-dependent signaling pathway in vitro and in vivo ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC8472231__F7 Expression Profile of New Gene Markers and Signaling Pathways Involved in Immunological Processes in Human Cumulus-Oophorus Cells ENSG00000051523 ENSG00000187608 ENSG00000089127 ENSG00000181104 ENSG00000157601 ENSG00000149294 ENSG00000168811 ENSG00000132530 ENSG00000103490 ENSG00000145623 ENSG00000122691 ENSG00000136869 ENSG00000140464 ENSG00000142627 ENSG00000117228 ENSG00000112964 ENSG00000125347 ENSG00000276561 ENSG00000067066 ENSG00000115884 ENSG00000108691 ENSG00000179344 ENSG00000118785 ENSG00000170458 ENSG00000026508 PMC8472231__F8 Expression Profile of New Gene Markers and Signaling Pathways Involved in Immunological Processes in Human Cumulus-Oophorus Cells ENSG00000169291 ENSG00000002330 ENSG00000070831 ENSG00000163914 PMC8472231__F9 Expression Profile of New Gene Markers and Signaling Pathways Involved in Immunological Processes in Human Cumulus-Oophorus Cells ENSG00000167207 ENSG00000149968 ENSG00000078747 ENSG00000102871 ENSG00000196549 ENSG00000166278 ENSG00000131323 ENSG00000168040 ENSG00000127191 ENSG00000164305 PMC2920345__F3 Viral tricks to grid-lock the type I interferon system ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000163497 PMC1312313__F8 NO• regulation of the cell cycle ENSG00000094804 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000101224 ENSG00000117399 PMC8472231__F6 Expression Profile of New Gene Markers and Signaling Pathways Involved in Immunological Processes in Human Cumulus-Oophorus Cells ENSG00000023445 ENSG00000019582 ENSG00000142627 ENSG00000111057 ENSG00000112964 ENSG00000179344 ENSG00000170458 ENSG00000026508 ENSG00000277263 ENSG00000125347 ENSG00000077782 ENSG00000276561 PMC12049846__F7 Mechanisms ENSG00000151276 ENSG00000164935 ENSG00000067900 ENSG00000102575 ENSG00000131196 ENSG00000143387 PMC5446554__F1 Highly simplified overview of various functions of the mitochondrion, adjusted to highlight the steps catalyzed by enzymes for which the respective encoding genes were studied in this work ENSG00000291958 ENSG00000105953 PMC5384497__F1 Schematic view of the anti-inflammatory roles of SLPI in obesity-related atherosclerosis pathway ENSG00000124107 ENSG00000136869 PMC6661007__F2 Pathobiology of inherited biliary diseases: a roadmap to understand acquired liver diseases ENSG00000157764 ENSG00000167323 ENSG00000293604 ENSG00000112715 PMC6661007__F3 Pathobiology of inherited biliary diseases: a roadmap to understand acquired liver diseases ENSG00000169245 ENSG00000162711 ENSG00000107562 ENSG00000163739 ENSG00000168610 PMC8617635__F9 Riboflavin as a Mucosal Adjuvant for Nasal Influenza Vaccine ENSG00000132478 ENSG00000126353 PMC9170998__F3 Traditional Uses, Phytochemistry and Biological Activities of Alocasia Species: A Systematic Review ENSG00000135446 ENSG00000120868 PMC4496240__F7 Inactivation of bone morphogenetic protein 2 may predict clinical outcome and poor overall survival for renal cell carcinoma through epigenetic pathways ENSG00000170365 ENSG00000123374 ENSG00000116717 PMC11969448__F1 miRNA-dependent resistance mechanisms to anti-hormonal therapies in estrogen receptor-positive breast cancer patients ENSG00000134982 ENSG00000135446 ENSG00000198793 ENSG00000168036 ENSG00000123374 ENSG00000105810 ENSG00000171791 ENSG00000146648 PMC12027374__F2 LH on spermatogenesis, LCs, and sperm cells ENSG00000146648 PMC12027374__F3 LH regulates testosterone synthesis in LCs through multiple pathways ENSG00000146648 PMC2291030__F3 EGF signaling pathway generated by the Ingenuity Pathway Analysis (IPA) software ENSG00000138798 ENSG00000124181 ENSG00000168610 PMC4919564__F1 Regulation of AMPK by metabolic stress, LKB1, and intracellular Ca++ ENSG00000198793 ENSG00000113161 ENSG00000106459 PMC6850886__F12 How PPM1H counteracts LRRK2 signaling pathway by dephosphorylating Rab proteins ENSG00000172780 ENSG00000111237 ENSG00000069329 ENSG00000084733 ENSG00000111110 ENSG00000111737 PMC7407194__F1 Autophagic Machinery ENSG00000177169 ENSG00000110497 ENSG00000123395 ENSG00000198382 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC7407194__F2 DSB repair ENSG00000188486 ENSG00000149311 ENSG00000101773 ENSG00000080345 ENSG00000197299 ENSG00000051180 ENSG00000187736 ENSG00000139618 PMC4919564__F2 Representative signaling in the AMPK pathway by various AMPK activators ENSG00000198793 ENSG00000159346 ENSG00000285070 ENSG00000096717 PMC7407194__F3 Main pathways regulating the DDR-mediated autophagic response ENSG00000143799 ENSG00000149311 ENSG00000177169 ENSG00000110497 ENSG00000168209 ENSG00000123395 ENSG00000198382 ENSG00000275700 ENSG00000023287 ENSG00000155792 PMC9116923__F3 Autophagy and Renal Fibrosis ENSG00000177169 ENSG00000069482 ENSG00000083290 ENSG00000198793 ENSG00000171791 ENSG00000145782 ENSG00000139112 PMC3276397__F1 Effects of VitA in gut-associated lymphoid tissue ENSG00000049768 PMC10887144__F1 In vitro liver organoid model creation ENSG00000019991 ENSG00000099985 ENSG00000138798 ENSG00000256762 PMC10648512__F3 Effect of exosomes derived from glioma stem cells and containing miR-26a on the BBB ENSG00000133937 ENSG00000198793 PMC4410569__F7 HJV and HFE Play Distinct Roles in Regulating Hepcidin ENSG00000010704 ENSG00000106327 PMC9662265__F1 Exosomes as a Cell-free Therapy for Myocardial Injury Following Acute Myocardial Infarction or Ischemic Reperfusion ENSG00000178860 ENSG00000170989 ENSG00000265972 ENSG00000110693 PMC3688919__F8 microRNAs Involved in Regulating Spontaneous Recovery in Embolic Stroke Model ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000173673 ENSG00000198793 ENSG00000164690 ENSG00000108821 ENSG00000128602 ENSG00000277641 ENSG00000168610 ENSG00000124762 PMC7555132__F3 Cdc48-dependent MAD and mitochondrial quality control mechanisms ENSG00000116688 ENSG00000158828 ENSG00000159459 ENSG00000086758 PMC12162925__F7 Integrating transcriptomics and metabolomics data ENSG00000130208 ENSG00000042832 ENSG00000113161 ENSG00000154059 PMC9675748__F6 Consequences of HDAC6 activity inhibition regulation through TubA treatment in DMD mice model ENSG00000094631 ENSG00000198793 PMC8383741__F7 IP-10 Promotes Latent HIV Infection in Resting Memory CD4+ T Cells via LIMK-Cofilin Pathway ENSG00000186810 ENSG00000106683 ENSG00000070831 ENSG00000121966 PMC6881211__F9 Emerging roles of the long non-coding RNA 01296/microRNA-143-3p/MSI2 axis in development of thyroid cancer ENSG00000153944 ENSG00000168610 PMC6514059__F2 Expression of the NCRs and their Ligands ENSG00000132646 ENSG00000164136 ENSG00000116962 PMC7467481__F1 Balance between thrombosis and bleeding in liver disease ENSG00000281244 ENSG00000003436 ENSG00000122194 PMC7175458__F4 Classic AHR signaling pathway ENSG00000171759 ENSG00000106546 PMC3356574__F3 The signaling pathways regulating radiation-induced bystander effects through expression and secretion of soluble biologically active factors ENSG00000149311 ENSG00000138795 ENSG00000137033 ENSG00000168610 ENSG00000140443 PMC9333350__SF1 TLR9 signaling pathways ENSG00000239732 ENSG00000172936 ENSG00000110057 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC8065911__F7 Schematic diagram showing the effects of ABZ on STAT3/5 signaling pathway via modulating SHP-1 expression ENSG00000291971 ENSG00000168610 PMC5217513__F1 AXL structure and effector pathways.Notes: Shown are the primary structural determinants impacting AXL activation and signaling ENSG00000167601 ENSG00000291971 PMC8276817__F2 Molecular targets for FAK inhibitor combination therapy ENSG00000168036 ENSG00000131023 PMC3539509__F2 TLR4 signaling pathway: TLR4 is localized on cell surface for ligand recognition and activates both MyD88-dependent pathway and TRIF-dependent pathway ENSG00000183735 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC2423434__F5 Dynamically asserted instances of interactions ENSG00000170967 ENSG00000197312 ENSG00000134982 PMC7309610__F2 Innate immune pattern recognition of bacterial lipids on OMVs leads to inflammation and death ENSG00000162711 ENSG00000170458 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC7296058__F4 G6PD in cancers ENSG00000165119 ENSG00000168036 ENSG00000151929 ENSG00000130669 ENSG00000125968 ENSG00000079999 PMC10975841__F4 Dietary Factors on DNA Methylation Levels of TNF-Alpha Gene and Proteome Profiles in Obese Men ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000104894 PMC7296058__F1 Pentose phosphate pathway (PPP) ENSG00000197713 PMC3436816__F2 EnrichNet: network-based gene set enrichment analysis ENSG00000047410 ENSG00000186575 ENSG00000099985 ENSG00000134982 ENSG00000186716 ENSG00000164485 ENSG00000146648 ENSG00000139687 ENSG00000117322 ENSG00000107789 ENSG00000106546 PMC7532093__F8 Protein-protein interaction network of hsa-miR-30a-5p-related DEGs ENSG00000110721 ENSG00000158014 ENSG00000165891 ENSG00000149294 ENSG00000171791 ENSG00000172795 ENSG00000112419 ENSG00000178445 ENSG00000048740 ENSG00000069667 ENSG00000113742 ENSG00000154359 ENSG00000007038 ENSG00000178573 ENSG00000108924 ENSG00000010810 ENSG00000064655 ENSG00000125850 ENSG00000151617 ENSG00000100625 ENSG00000173456 ENSG00000198947 ENSG00000175305 PMC11855089__F8 Comprehensive analysis of metabolomics and network pharmacology ENSG00000187475 ENSG00000124575 ENSG00000184357 ENSG00000187837 ENSG00000154059 PMC7532093__F9 Protein-protein interaction network ENSG00000118058 ENSG00000123975 ENSG00000101751 ENSG00000107562 ENSG00000063322 ENSG00000135823 ENSG00000069329 ENSG00000181690 ENSG00000035928 ENSG00000164305 ENSG00000141298 ENSG00000004478 ENSG00000248905 ENSG00000121542 ENSG00000138613 ENSG00000124882 ENSG00000174579 ENSG00000157064 ENSG00000149480 PMC156764__F1 NEW EMBO MEMBER’S REVIEW ENSG00000102871 ENSG00000173039 ENSG00000172936 ENSG00000168040 ENSG00000175104 PMC7367602__F1 Microarray-based Analysis of Genes, Transcription Factors, and Epigenetic Modifications in Lung Cancer Exposed to Nitric Oxide ENSG00000284774 ENSG00000072657 ENSG00000133116 ENSG00000102007 ENSG00000181409 ENSG00000154016 PMC7464161__F8 Possible mechanism of action of metformin and everolimus in QGP-1 and H727 cells ENSG00000110711 ENSG00000169047 ENSG00000198793 PMC7869416__F6 Schematic diagram illustrating Eif2s3y functions in goat SSCs PMC6358305__F1 Schematic biochemical pathway for the production of bioactive chemical mediators leukotriene C4 (LTC4) and leukotriene B4 (LTB4) ENSG00000226275 PMC6358305__F2 Incorporation of arachidonic acid into membrane-bound phospholipids by the Lands pathway () ENSG00000285482 ENSG00000166278 ENSG00000120437 ENSG00000075239 ENSG00000062282 PMC6837928__F1 Folate metabolism and interaction with other nutrients such as vitamin B12 and choline ENSG00000228716 PMC4506441__F5 Distribution of target proteins on the compressed ‘influenza-related pathway’ ENSG00000064601 ENSG00000143839 ENSG00000137193 ENSG00000105656 ENSG00000163751 ENSG00000122194 ENSG00000168610 ENSG00000113441 ENSG00000007171 ENSG00000133019 ENSG00000196549 ENSG00000123213 ENSG00000197943 ENSG00000123374 ENSG00000121060 ENSG00000146648 ENSG00000135517 ENSG00000164342 PMC7788045__F6 Schematic illustrating the Sirt1–FGF21 axis and vilda-mediated cardiac protection ENSG00000197635 ENSG00000105550 ENSG00000096717 PMC314316__F1 Schematic model indicating the presence of two potential insulin receptor–dependent signal transduction pathways ENSG00000134982 ENSG00000220205 PMC7316884__F1 De novo ceramide synthesis pathway and its hormonal regulators in adipose tissue ENSG00000139624 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000136869 ENSG00000119537 ENSG00000143418 PMC4860032__F1 The metabolism, analysis, and targeting of steroid hormones in breast and prostate cancer ENSG00000277893 PMC3824660__F2 Interrelations between autophagy-related signaling and cell growth control in response to stress ENSG00000128272 ENSG00000144895 ENSG00000169047 ENSG00000198793 PMC7796305__F3 Role of the Renin–Angiotensin–Aldosterone System in Dystrophin-Deficient Cardiomyopathy ENSG00000130234 PMC7796305__F2 Complex network of interplayed cellular and molecular mechanisms that participle in the development of myocardial fibrosis leading to the occurrence of dystrophin-deficient cardiomyopathy ENSG00000124102 PMC6274739__F2 Basic TGFB signaling diagram along with a program of TGFBeta-regulated genes that contribute to the EMT ENSG00000170961 ENSG00000169554 ENSG00000122691 ENSG00000198742 ENSG00000170558 ENSG00000163914 ENSG00000104413 ENSG00000175104 ENSG00000076604 PMC5917448__F12 1-Deoxynojirimycin on gastric ulcer by affecting NFKB pathway PMC3608642__F4 Multiple Single-Cell Genomes Provide Insight into Functions of Uncultured Deltaproteobacteria in the Human Oral Cavity ENSG00000198846 ENSG00000127948 PMC8622657__F3 Fibroblast Growth Factor (FGF) Signaling in Tissue Repair and Regeneration ENSG00000110395 PMC6023839__F5 Regulatory Network and Crosstalk Analysis for Gene Set(A) KEGG pathway network formed by relapse gene sets ENSG00000160789 ENSG00000167207 ENSG00000134982 ENSG00000154639 ENSG00000080819 ENSG00000060138 ENSG00000155792 ENSG00000162772 ENSG00000038002 ENSG00000116161 ENSG00000177426 ENSG00000198742 ENSG00000106070 ENSG00000136997 ENSG00000092067 ENSG00000101333 ENSG00000143995 ENSG00000169554 ENSG00000108510 ENSG00000143507 ENSG00000185129 ENSG00000162104 ENSG00000123066 ENSG00000163629 ENSG00000175352 ENSG00000087586 ENSG00000092820 ENSG00000106546 ENSG00000284017 ENSG00000196549 ENSG00000175189 ENSG00000120458 ENSG00000102098 ENSG00000115942 ENSG00000034693 ENSG00000081041 ENSG00000169896 ENSG00000108055 ENSG00000119471 ENSG00000169439 ENSG00000107447 ENSG00000124766 ENSG00000087460 ENSG00000277943 ENSG00000111725 ENSG00000276068 ENSG00000024526 ENSG00000101849 ENSG00000177606 ENSG00000255398 ENSG00000072110 ENSG00000005381 ENSG00000138760 ENSG00000114166 PMC3549334__F7 Ras activation by •NO-mediated processes in pancreatic cancer ENSG00000006451 ENSG00000144118 PMC5559481__F1 LncRNAs serve as p53 regulators and effectors, participating in the p53 regulatory pathway PMC4855107__F1 Arachidonic acid (AA) metabolism involved in the pathogenic mechanisms of nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity ENSG00000226275 PMC6581604__F7 LMNA mechanosensing based on a ‘lose it or use it’ mechanism for tension-inhibited turnover that also applies to collagen-I ENSG00000160789 ENSG00000087245 PMC9030951__F1 The Homeostatic Unfolded Protein Response in Diabetic Nephropathy ENSG00000128272 ENSG00000144895 ENSG00000134982 ENSG00000265972 ENSG00000100219 PMC4629125__F1 Intrahepatic interplays among hepatocytes, non-parenchymal cells (NPC) and lymphocytes and illustration of antiviral and immunotherapeutic strategies ENSG00000183735 ENSG00000159128 ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000027697 ENSG00000172936 ENSG00000150455 ENSG00000164342 ENSG00000142166 PMC5659737__F1 Review of Markers of Zona Glomerulosa and Aldosterone-Producing Adenoma Cells ENSG00000138795 ENSG00000105329 ENSG00000134982 ENSG00000179142 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC4833509__F7 Two-Step Reactivation of Dormant Cones in Retinitis Pigmentosa ENSG00000197713 ENSG00000265972 ENSG00000026103 PMC5828779__F5 Toll-like receptor signaling pathways in the prefrontal cortex ENSG00000169245 ENSG00000183735 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC6581604__F1 Contractility or collagen perturbations result in rapid ~1h changes in LMNA, DNA damage, and cell cycle ENSG00000188486 ENSG00000160789 ENSG00000141086 PMC7769821__F4 KEGG pathway schematic diagram of inflammatory bowel disease (IBD) ENSG00000134982 ENSG00000164399 ENSG00000113520 ENSG00000128342 PMC9030951__F3 The Homeostatic Unfolded Protein Response in Diabetic Nephropathy ENSG00000134982 ENSG00000100219 ENSG00000096717 PMC7769821__F5 KEGG pathway schematic diagram of cytokine-cytokine receptor interaction ENSG00000155926 ENSG00000128342 PMC3031466__F10 A PtdIns(3)P-mediated signaling pathway that drives the degradation of apoptotic cells ENSG00000129515 ENSG00000111237 ENSG00000028528 PMC3383846__F2 Signaling pathways that regulate cytokine AREs post-transcriptionally ENSG00000136869 PMC5629024__F3 Gene networks with the genes in core from GSEA analysis ENSG00000111057 ENSG00000142192 ENSG00000131747 ENSG00000184451 ENSG00000276644 ENSG00000168036 ENSG00000181690 ENSG00000121807 ENSG00000136014 ENSG00000132846 ENSG00000165409 ENSG00000133816 ENSG00000139289 ENSG00000197763 ENSG00000112182 ENSG00000214063 ENSG00000171819 PMC4003375__F1 Nck proteins as the newly identified adaptors between the BCR complex and BCAP/PI3K/Akt pathway ENSG00000177455 ENSG00000002330 ENSG00000150907 ENSG00000010671 PMC8278735__F6 Ferulic acid inhibits LPS-induced apoptosis in bovine mammary epithelial cells by regulating the NFKB and Nrf2 signalling pathways to restore mitochondrial dynamics and ROS generation ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000079999 PMC3648215__F1 Androgen regulation of epithelial–mesenchymal transition in prostate tumorigenesis ENSG00000138795 ENSG00000168036 PMC8395114__F6 Clavibacter michiganensis Downregulates Photosynthesis and Modifies Monolignols Metabolism Revealing a Crosstalk with Tomato Immune Responses ENSG00000291931 ENSG00000166484 PMC3641677__F4 Mechanisms that Regulate Stem Cell Aging and Life Span ENSG00000140443 PMC8787342__F1 Activated Macrophage – A Tough Fortress for Virus Invasion: How Viruses Strike Back ENSG00000108691 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000137699 ENSG00000169429 ENSG00000172936 ENSG00000136869 ENSG00000276561 ENSG00000164342 PMC3500850__F4 Temporal molecular and biological assessment of an erlotinib-resistant lung adenocarcinoma model reveals markers of tumor progression and treatment response ENSG00000173221 ENSG00000159399 PMC9306048__F7 Forkhead Box S1 mediates epithelial-mesenchymal transition through the Wnt/Beta-catenin signaling pathway to regulate colorectal cancer progression ENSG00000137673 ENSG00000134982 ENSG00000170558 ENSG00000168036 PMC3679382__F8 Working model of the FGF21 regulatory pathway under leucine deprivation ENSG00000128272 ENSG00000144895 ENSG00000105550 ENSG00000026103 PMC4040351__F2 From Fly Wings to Targeted Cancer Therapies: A Centennial for Notch Signaling ENSG00000128917 ENSG00000148400 ENSG00000074181 ENSG00000136997 ENSG00000126353 ENSG00000171791 ENSG00000184916 ENSG00000114315 ENSG00000090932 ENSG00000109670 PMC4040351__F4 From Fly Wings to Targeted Cancer Therapies: A Centennial for Notch Signaling ENSG00000198793 ENSG00000168036 ENSG00000114315 PMC7143722__F3 De-novo fatty acid synthesis in oleaginous microorganisms (adapted from [,,,,,]), and enzymes involved in lipid accumulation ENSG00000152266 ENSG00000134824 ENSG00000198670 ENSG00000026103 PMC5133788__F10 11-epi-SA-induced apoptotic pathway in HA22T cancer cells ENSG00000128272 ENSG00000002330 ENSG00000144895 ENSG00000177606 ENSG00000127191 PMC10037167__F1 Myostatin silencing inhibits podocyte apoptosis in membranous nephropathy through Smad3/PKA/NOX4 signaling pathway ENSG00000086991 PMC8088836__F4 PH Regulation in the Tumor Microenvironment (TME) ENSG00000134086 ENSG00000198793 ENSG00000166816 PMC3139433__F4 Identification of predictive markers of cytarabine response in AML by integrative analysis of gene-expression profiles with multiple phenotypes ENSG00000128656 ENSG00000291971 ENSG00000132824 ENSG00000169047 ENSG00000175591 ENSG00000168036 ENSG00000135341 ENSG00000112715 ENSG00000230797 ENSG00000124762 ENSG00000038382 ENSG00000171720 ENSG00000128052 ENSG00000136997 ENSG00000115138 ENSG00000116030 ENSG00000118257 ENSG00000139687 ENSG00000105404 ENSG00000168495 ENSG00000253729 ENSG00000158691 ENSG00000127337 ENSG00000026103 ENSG00000157764 ENSG00000008086 ENSG00000167074 ENSG00000013503 ENSG00000066468 ENSG00000180447 ENSG00000260027 ENSG00000176884 ENSG00000185386 ENSG00000244687 ENSG00000164061 ENSG00000010810 ENSG00000177606 ENSG00000100813 ENSG00000149554 ENSG00000100034 PMC5647233__F4 Hypothetical roles of ANTXR1 as a modulator of HbF expression PMC8636224__F1 Formation, contents, functions of exosomes and their potential in lung cancer diagnostics and therapeutics ENSG00000074319 ENSG00000110651 ENSG00000010278 ENSG00000135404 ENSG00000165527 ENSG00000146648 PMC3206202__F10 Expression Profiling Reveals Differential Gene Induction Underlying Specific and Non-Specific Memory for Pheromones in Mice ENSG00000291507 ENSG00000069482 ENSG00000105656 PMC8870287__F2 Research Progress on Neuroprotection of Insulin-like Growth Factor-1 towards Glutamate-Induced Neurotoxicity ENSG00000002330 ENSG00000198793 ENSG00000140443 PMC8036595__F7 Mg2+ and Gd3+ interfere with phosphate-induced SOCE upregulation by the activation of CaSR in megakaryocytes—a schematic representation ENSG00000102908 ENSG00000167323 ENSG00000293604 ENSG00000118515 ENSG00000036828 PMC11640972__F2 Tryptophan metabolic pathways PMC4361250__F4 Hedgehog signaling in prostate epithelial-mesenchymal growth regulation ENSG00000106571 ENSG00000128602 PMC10451954__F1 Primary Coenzyme Q10 Deficiency: An Update ENSG00000132423 ENSG00000115520 ENSG00000167113 ENSG00000123815 ENSG00000119723 ENSG00000163050 ENSG00000110871 ENSG00000088682 ENSG00000148459 ENSG00000173085 ENSG00000167186 ENSG00000135469 PMC8220142__F4 Dual Characters of GH-IGF1 Signaling Pathways in Radiotherapy and Post-radiotherapy Repair of Cancers ENSG00000149311 ENSG00000112964 ENSG00000137699 ENSG00000140443 PMC2951628__F1 Inflammation Joins the “Niche” ENSG00000143546 ENSG00000163220 ENSG00000136869 PMC7101072__F1 Research Priorities for Heart Failure with Preserved Ejection Fraction: National Heart, Lung, and Blood Institute Working Group Summary ENSG00000175206 ENSG00000120937 PMC8895466__F1 Cell-based immunotherapy of glioblastoma multiforme ENSG00000182578 ENSG00000184371 ENSG00000121966 PMC3874419__F1 Signaling cross-talk at the various levels of EGFR/HER2 signaling pathways ENSG00000198793 ENSG00000146648 PMC8082181__F10 Trilobatin, a Component from Lithocarpus polystachyrus Rehd., Increases Longevity in C. elegans Through Activating SKN1/SIRT3/DAF16 Signaling Pathway ENSG00000142082 PMC10722483__F6 Acupoint catgut embedding attenuates fibromyalgia pain through attenuation of TRPV1 signaling pathway in mouse ENSG00000198793 ENSG00000196689 PMC4443744__F5 Crosstalk between complement and TLR pathways ENSG00000172936 ENSG00000136869 PMC3512410__F2 Scheme depicting the different outcomes caused by the presence of progerin and prelamin in cells ENSG00000149311 ENSG00000175054 ENSG00000168036 ENSG00000162521 PMC9509045__F5 Bioinformatic identification of differentially expressed genes associated with hepatocellular carcinoma prognosis ENSG00000145604 ENSG00000094804 ENSG00000108055 ENSG00000170458 ENSG00000132646 ENSG00000115942 ENSG00000123374 ENSG00000135336 ENSG00000205250 ENSG00000166851 ENSG00000276876 ENSG00000093009 PMC10534805__F9 Lonicera Caerulea Juice Alleviates Alcoholic Liver Disease by Regulating Intestinal Flora and the FXR-FGF15 Signaling Pathway ENSG00000042832 ENSG00000167910 ENSG00000145113 ENSG00000293532 PMC9262551__F3 Relevance of NLRP3 Inflammasome-Related Pathways in the Pathology of Diabetic Wound Healing and Possible Therapeutic Targets ENSG00000162711 ENSG00000198793 ENSG00000265972 PMC8268744__F1 Structural and Drug Targeting Insights on Mutant p53 ENSG00000135423 ENSG00000175793 ENSG00000156709 ENSG00000288174 ENSG00000116717 ENSG00000171791 ENSG00000158169 ENSG00000112715 ENSG00000124762 ENSG00000136048 ENSG00000121966 ENSG00000149311 ENSG00000175054 ENSG00000134574 ENSG00000134057 ENSG00000089685 ENSG00000078237 ENSG00000120868 ENSG00000284194 ENSG00000095002 ENSG00000140464 ENSG00000026103 PMC4533861__F7 CX3CL1-induced breast carcinogenesis in ErbB2 transgenic mice ENSG00000168329 ENSG00000113070 ENSG00000166278 PMC11019510__F5 Role and mechanism of TXNDC5 in disease progression PMC4325379__F1 An overview of melanocyte development ENSG00000157404 ENSG00000080166 ENSG00000107165 ENSG00000100146 PMC9131939__F14 Deciphering miR-520c-3p as a probable target for immunometabolism in non-small cell lung cancer using systems biology approach ENSG00000149311 ENSG00000175054 ENSG00000168610 PMC6030854__F1 The effects of the Insulin-like Growth Factor 1 (IGF-1) on muscle growth and homeostasis ENSG00000155792 ENSG00000140443 PMC7991804__F2 An overview of mechanisms of GC resistance in ALL and pharmacological strategies to overcome it ENSG00000122025 ENSG00000198793 ENSG00000118515 ENSG00000145321 ENSG00000292363 ENSG00000171791 ENSG00000114315 PMC8115323__F1 WNK-SPAK-NCC pathway and WNK ubiquitination by the CUL3-KLHL3 E3 ubiquitin ligase complex ENSG00000126562 ENSG00000143867 ENSG00000060237 ENSG00000146021 PMC3881016__F5 Pathway analysis of iron deficiency associated chlorosis ENSG00000105664 ENSG00000148377 PMC8032689__F10 The MAF-TGFB1-crystallin axis that underlies the pathological growth of lens in high myopia ENSG00000178573 PMC6472122__F5 Transfer RNA-derived fragment target genes in the Kyoto Encyclopedia of Genes and Genomes AMPK pathway map generated using DAVID software ENSG00000180210 ENSG00000171105 ENSG00000135218 ENSG00000005882 ENSG00000198793 ENSG00000001626 ENSG00000026103 PMC8825743__F3 Notch signaling in the pathogenesis, progression and identification of potential targets for cholangiocarcinoma (Review) ENSG00000142627 ENSG00000198793 ENSG00000111321 PMC3208056__F4 Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/Beta-catenin/cyclin D1 signaling pathway in rats ENSG00000134982 ENSG00000168036 ENSG00000171791 PMC8351444__F7 MYC: a multipurpose oncogene with prognostic and therapeutic implications in blood malignancies ENSG00000102034 ENSG00000291971 ENSG00000186716 ENSG00000136997 PMC3959161__F2 Deconstructing the roles of glucocorticoids in adipose tissue biology and the development of central obesity ENSG00000042832 ENSG00000145321 ENSG00000285482 ENSG00000124253 ENSG00000026103 PMC3255319__F1 Oncogenic and tumor suppressor control of metabolism ENSG00000131473 ENSG00000134086 ENSG00000092621 ENSG00000198793 ENSG00000169710 ENSG00000159399 ENSG00000196712 PMC3260854__F6 FosB-mediated regulation of ECM genes by mechanical signaling in bladder smooth muscle ENSG00000125740 ENSG00000041982 ENSG00000177606 PMC5870354__F2 SignalingEpithelial growth factor receptor signal transduction ENSG00000115415 ENSG00000138798 ENSG00000198793 ENSG00000124181 ENSG00000168610 ENSG00000146648 PMC6213175__F3 Select HCMV gene products that target apoptotic pathways during HCMV infection ENSG00000198793 ENSG00000168040 PMC4028977__F1 Targeting inflammation: multiple innovative ways to reduce prostaglandin E2 PMC2674743__F2 Altered insulin signaling by lipid intermediates ENSG00000198793 ENSG00000026103 PMC9100777__F1 Bilayer Forming Phospholipids as Targets for Cancer Therapy ENSG00000138018 ENSG00000185813 ENSG00000174915 ENSG00000173599 ENSG00000156471 ENSG00000241878 ENSG00000133027 PMC4340906__F5 Induction of Indoleamine 2, 3-Dioxygenase in Human Dendritic Cells by a Cholera Toxin B Subunit—Proinsulin Vaccine ENSG00000173163 ENSG00000011600 ENSG00000077150 ENSG00000150991 ENSG00000151012 ENSG00000115415 ENSG00000109320 ENSG00000177606 ENSG00000106546 PMC8204302__F7 Host determinants of disease severity in acute cystitis; mechanism of IL-1B and SP hyperactivation ENSG00000162711 ENSG00000039537 ENSG00000137673 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC4622840__F1 c-Met-mediated oncogenic signaling (from Peruzzi et al) ENSG00000019991 ENSG00000154059 PMC6093675__F6 Striatal transcriptome of a mouse model of ADHD reveals a pattern of synaptic remodeling ENSG00000157851 ENSG00000178585 ENSG00000168036 ENSG00000114019 PMC8508740__F1 New Fast Acting Glucagon for Recovery from Hypoglycemia, a Life-Threatening Situation: Nasal Powder and Injected Stable Solutions ENSG00000100994 PMC6236198__F6 Cell cycle pathway (the chart is from the KEGG database, gene symbolized by ★ and correlation P values can be found in ) ENSG00000145604 ENSG00000108055 ENSG00000132646 ENSG00000115942 ENSG00000123374 ENSG00000277273 ENSG00000117399 ENSG00000276876 ENSG00000093009 PMC3412962__F4 A, Differential expression of proteins involved in glycolysis and TCA cycle ENSG00000166816 ENSG00000137055 PMC9282876__F7 Sanguinarine Regulates Tumor-Associated Macrophages to Prevent Lung Cancer Angiogenesis Through the WNT/Beta-Catenin Pathway ENSG00000154764 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000188064 ENSG00000169884 ENSG00000168036 ENSG00000125084 PMC8622894__F2 Plasma Ceramides Pathophysiology, Measurements, Challenges, and Opportunities ENSG00000100422 ENSG00000102172 ENSG00000113163 ENSG00000135587 PMC1069556__F6 Effect of NS5A on the Beta-catenin signaling pathway ENSG00000002330 ENSG00000168036 ENSG00000167074 PMC8081964__F3 MicroRNA Expression Changes and Integrated Pathways Associated With Poor Outcome in Canine Osteosarcoma ENSG00000143799 ENSG00000148400 ENSG00000109320 ENSG00000026508 ENSG00000168036 ENSG00000133961 ENSG00000114315 ENSG00000128602 ENSG00000139687 ENSG00000124762 ENSG00000106003 ENSG00000140443 PMC4097927__F4 Polyamidoamine dendrimer-based gene delivery vectors ENSG00000188158 ENSG00000166278 ENSG00000182326 ENSG00000062485 PMC7689704__F8 Pipoxolan suppresses the inflammatory factors of NF‐KB, AP‐1, and STATs, but activates the antioxidative factor Nrf2 in LPS‐stimulated RAW 264.7 murine macrophage cells ENSG00000170458 ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000168610 PMC4019579__F8 NAMPT-Mediated Salvage Synthesis of NAD+ Controls Morphofunctional Changes of Macrophages ENSG00000105835 ENSG00000070831 ENSG00000163914 ENSG00000136869 ENSG00000182541 PMC3667651__F3 Mechanisms underlying molecularly targeted therapeutics-induced cardiac toxicity ENSG00000291971 PMC7407594__F2 RNA sensing mechanisms ENSG00000026297 ENSG00000089127 ENSG00000185745 ENSG00000172936 ENSG00000135828 ENSG00000164342 PMC7407594__F4 Posttranscriptional mechanisms by RNA-binding proteins (RBPs) regulating mRNA stability ENSG00000196843 ENSG00000136869 ENSG00000102921 ENSG00000172795 ENSG00000198286 PMC6108877__F7 Schematic representation of the anti-invasive effects of wogonin in LPS-stimulated MDA-MB-231 cells, via the 5-LO/BLT2 pathway ENSG00000172936 ENSG00000136869 PMC6329798__F1 ABPs used for caspase analysis ENSG00000132906 ENSG00000171791 ENSG00000064012 PMC7142844__F8 Molecular mechanisms of SNRPG-mediated p53 targeting of TMZ-induced glioblastoma multiforme (GBM) growth inhibition ENSG00000143977 ENSG00000134057 ENSG00000170430 ENSG00000123374 PMC2881215__F1 Signaling in podocyte apoptosis ENSG00000148400 ENSG00000198087 PMC7920062__F1 Bile acid metabolism ENSG00000167910 ENSG00000036530 ENSG00000135929 PMC7757049__F3 miR-340 is associated with various genes modulating cancer cell proliferation ENSG00000145604 ENSG00000138764 ENSG00000135446 ENSG00000168036 PMC6030169__F1 Intracellular exposure to intermediate ROS levels triggers conformational changes in KEAP1 via oxidation of its C-terminal cysteines, resulting in dissociation of the KEAP1-NRF2 complex and subsequent nuclear translocation of NRF2 ENSG00000156709 ENSG00000247077 ENSG00000079999 PMC7757049__F4 miR-340 is involved in the regulation of cancer cell apoptosis ENSG00000168036 ENSG00000151929 ENSG00000168610 PMC5788694__F4 Role of ginsenosides in reactive oxygen species-mediated anticancer therapy ENSG00000198793 ENSG00000144848 ENSG00000158517 ENSG00000057663 PMC7139912__F2 Symplified representation of pro-inflammatory mediators in Wobbler (Wr) mouse spinal cord ENSG00000162711 ENSG00000150782 ENSG00000189403 ENSG00000172936 ENSG00000136869 PMC5010532__F1 Adaptive UPR in Parkinson׳s disease ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC10622988__F4 Tumor-associated signaling pathways influenced by lncRNA SOX21-AS1 in breast cancer, lung adenocarcinoma, and glioma ENSG00000113645 ENSG00000186575 ENSG00000168036 ENSG00000127324 ENSG00000150457 PMC8996999__F1 Posttranslational Modifications in Thyroid Cancer: Implications for Pathogenesis, Diagnosis, Classification, and Treatment ENSG00000100234 ENSG00000105329 ENSG00000165409 ENSG00000262217 ENSG00000112715 PMC8996999__F2 Posttranslational Modifications in Thyroid Cancer: Implications for Pathogenesis, Diagnosis, Classification, and Treatment ENSG00000198793 ENSG00000168036 PMC6715251__F9 Adenovirus early region 3 RIDA protein limits NFKB signaling through stress-activated EGF receptors ENSG00000127445 ENSG00000274145 ENSG00000146648 PMC7432451__F1 ITAM- and ITIM-signaling receptors sense the microenvironment and determine the response of microglia ENSG00000162711 ENSG00000011600 ENSG00000198053 ENSG00000101307 ENSG00000291971 ENSG00000125538 PMC7818015__F4 DNA alkylation lesion repair: outcomes and implications in cancer chemotherapy ENSG00000125352 ENSG00000166199 ENSG00000108384 PMC4427577__F1 Signaling by TGFB family members through the Smad-dependent and Smad-independent pathways: TGFB induces its response by multimerization of TGFB receptor II (TBRII) and TGFB receptor I (TBRI) PMC6821048__F7 Inhibitory effects of butein on cell proliferation and TNF-Alpha-induced CCL2 release in racially different triple negative breast cancer cells ENSG00000102871 ENSG00000263528 ENSG00000168040 ENSG00000127191 ENSG00000064012 ENSG00000164305 PMC5473901__F8 Summary Effect of miR34a ENSG00000171791 PMC4803799__F3 mTOR in sensing autophagy signals : mTOR inhibition integrates amino acid starvation, growth factor deprivation, decreased ATP or oxygen levels, enhanced reactive oxygen species (ROS) to activate autophagy ENSG00000177169 ENSG00000112561 PMC4443744__F2 Role of complement in physiology ENSG00000137033 ENSG00000198793 ENSG00000203710 PMC4803799__F7 Teaching the basics of autophagy and mitophagy to redox biologists—Mechanisms and experimental approaches ENSG00000135655 ENSG00000110497 ENSG00000156735 ENSG00000158828 ENSG00000069509 ENSG00000135093 ENSG00000100225 ENSG00000175193 ENSG00000198742 ENSG00000175104 ENSG00000171109 ENSG00000016391 ENSG00000214253 PMC8464934__F2 Glutathione Metabolism in Plants under Stress: Beyond Reactive Oxygen Species Detoxification PMC3776718__F3 Overlay of the insulin-like growth factor-1 (IGF-1) signaling pathway with microarray data for comparison of very small embryonic-like stem cells (VSELs) with hematopoietic stem cells (HSCs) ENSG00000069869 ENSG00000002330 ENSG00000168610 ENSG00000140443 PMC7545020__F2 An aberrant STAT pathway is central to COVID-19 ENSG00000213928 ENSG00000105397 ENSG00000115415 PMC7545020__F3 An aberrant STAT pathway is central to COVID-19 ENSG00000105397 ENSG00000291971 ENSG00000138798 ENSG00000033800 ENSG00000168610 ENSG00000146648 PMC7545020__F4 An aberrant STAT pathway is central to COVID-19 ENSG00000170961 ENSG00000115415 ENSG00000136869 ENSG00000168610 ENSG00000132693 PMC5300050__F3 Macrophage Functions in Tissue Patterning and Disease: New Insights from the Fly ENSG00000135218 PMC7770133__F2 Summary of reverse MHC-I signaling pathways in various cell types ENSG00000087245 ENSG00000291603 ENSG00000157933 ENSG00000002330 ENSG00000291971 ENSG00000198793 ENSG00000162924 ENSG00000273686 ENSG00000168610 ENSG00000105397 ENSG00000125538 ENSG00000172936 ENSG00000175104 PMC8869911__F4 Dissecting Tumor Growth: The Role of Cancer Stem Cells in Drug Resistance and Recurrence ENSG00000168036 ENSG00000128602 PMC9454566__F9 Anti-Tumoral Effect of Chemerin on Ovarian Cancer Cell Lines Mediated by Activation of Interferon Alpha Response ENSG00000174600 ENSG00000213928 ENSG00000187608 ENSG00000143442 ENSG00000089127 ENSG00000155926 ENSG00000157601 ENSG00000185885 ENSG00000111331 ENSG00000205413 ENSG00000276561 PMC8968815__F1 Wnt/Beta-catenin signaling pathway related microRNAs in esophageal cancer ENSG00000197380 ENSG00000155011 ENSG00000050165 ENSG00000183579 ENSG00000168036 ENSG00000123374 ENSG00000106483 ENSG00000168610 PMC7765095__F2 KEGG GO pathways of selected apple Full-length cDNA OvereXpressing (FOX) Arabidopsis mutant lines ENSG00000163435 ENSG00000111837 ENSG00000116791 PMC3829661__F2 Schematic overview ofP ENSG00000173599 PMC9454566__F7 Anti-Tumoral Effect of Chemerin on Ovarian Cancer Cell Lines Mediated by Activation of Interferon Alpha Response ENSG00000096996 ENSG00000133106 ENSG00000089127 ENSG00000153094 ENSG00000137203 ENSG00000185745 ENSG00000111331 ENSG00000205413 ENSG00000175029 PMC9454566__F8 Anti-Tumoral Effect of Chemerin on Ovarian Cancer Cell Lines Mediated by Activation of Interferon Alpha Response ENSG00000152484 ENSG00000163539 ENSG00000213928 ENSG00000164430 ENSG00000133106 ENSG00000089127 ENSG00000185745 ENSG00000111331 ENSG00000205413 PMC4528065__F7 Model of CC-122 costimulation of T cells and tumoricidal activity through degradation of Aiolos and Ikaros ENSG00000167986 ENSG00000113851 ENSG00000276561 PMC4672198__F2 MITF function in the nucleus of a melanosome to activate melanin synthesis and secretion and melanocyte growth and survival ENSG00000157404 ENSG00000049130 ENSG00000135903 ENSG00000168036 ENSG00000136160 ENSG00000100146 ENSG00000124205 PMC6162501__F2 P53-ARF-MDM2/4 pathway (adapted from the p53 website) ENSG00000134899 ENSG00000159388 ENSG00000116717 ENSG00000140464 ENSG00000124762 ENSG00000026103 ENSG00000198625 PMC11881760__F3 Updating on the Dual Role of Salivary Gland Epithelial Cell (SGEC) in Sjögren’s Disease ENSG00000162711 ENSG00000164430 ENSG00000163568 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC6790574__F5 Inflammasome ENSG00000278718 ENSG00000162711 ENSG00000226275 ENSG00000163568 ENSG00000174885 ENSG00000091592 ENSG00000091106 ENSG00000168040 ENSG00000276068 PMC6790574__F3 Nucleic acid sensors ENSG00000183735 ENSG00000164430 PMC6790574__F1 TLR‐mediated signaling pathway ENSG00000183735 ENSG00000239732 ENSG00000111537 ENSG00000134070 ENSG00000113520 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000164342 PMC4985489__F2 Recommendations for Development of Botanical Polyphenols as “Natural Drugs” for Promotion of Resilience Against Stress-Induced Depression and Cognitive Impairment ENSG00000198793 ENSG00000103942 PMC3151103__F9 Schematic summary of a signaling pathway underlying IL-1Beta-induced dedifferentiation of primary cultured articular chondrocytes ENSG00000105835 ENSG00000125398 ENSG00000096717 PMC6234654__F9 Diagrammatic representation of occurrence of colorectal cancer (a) and various modulatory mechanisms of combinatorial administration of probiotics and celecoxib (b) in CRC with respect to different biomarkers ENSG00000134982 ENSG00000125538 PMC1905729__F1 Binding of IL-12 to the IL-12RB1 and B2 chains induces phosphorylation of the kinases Tyk2 and Jak2, which associate with the cytoplasmic tails of the B1 and B2 chains, respectively ENSG00000096996 ENSG00000105397 PMC2876151__F7 Cdk1 modulates the activity of several DNA damage checkpoint proteins ENSG00000260314 ENSG00000138346 ENSG00000163918 ENSG00000133119 ENSG00000117399 PMC8725472__F8 SCUBE3 downregulation modulates hepatocellular carcinoma by inhibiting CCNE1 via TGFB/PI3K/AKT/GSK3B pathway ENSG00000123374 ENSG00000146197 PMC4431663__F1 Physiological regulation and pharmacological inhibition of the STAT3 signalling pathway ENSG00000168610 PMC8201651__F1 Wnt/Beta-Catenin Signaling and Liver Regeneration: Circuit, Biology, and Opportunities ENSG00000281324 ENSG00000162337 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC6321330__F1 Simplified representation showing the interplay between the major signaling cascades activated by tyrosine kinase receptors (RTKs) and TSH-Receptor (TSH-R) ENSG00000198793 ENSG00000165409 PMC11474142__F3 Major signaling pathways associated with ENPP1 ENSG00000164430 ENSG00000171791 PMC8207832__F2 Ubiquitin-dependent protein assembly at DSBs and their roles in DSB repair pathway choice ENSG00000149311 ENSG00000012048 ENSG00000083093 ENSG00000138346 ENSG00000102226 ENSG00000080345 ENSG00000168411 ENSG00000051180 ENSG00000112130 ENSG00000139618 ENSG00000276043 ENSG00000079999 PMC9336077__F2 Molecular biology and therapeutic potential of Nrf2 in leukemia ENSG00000100387 ENSG00000113558 ENSG00000185483 ENSG00000156273 ENSG00000079999 PMC8511501__F1 Polydatin Ameliorates Osteoporosis via Suppression of the Mitogen-Activated Protein Kinase Signaling Pathway ENSG00000163464 ENSG00000110711 ENSG00000173039 ENSG00000169032 ENSG00000121807 ENSG00000196396 ENSG00000106546 ENSG00000179295 ENSG00000138735 ENSG00000169245 ENSG00000186810 ENSG00000108691 ENSG00000177189 ENSG00000197971 PMC6770560__F9 Coelonin inhibiting LPS-stimulated activation of NFKB and inducing G1 phase cell-cycle arrest in RAW264.7 cells ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC3679471__F6 MSP-RON signaling pathway ENSG00000108691 ENSG00000111537 ENSG00000136869 ENSG00000121807 PMC12103590__F8 Proposed model of hnRNPL phase separation promoting glycolysis in ovarian cancer PMC3309874__F1 Insulin/insulin-like growth factor-1 (IGF-1) signaling (IIS) is a major candidate pathway in human longevity ENSG00000171105 ENSG00000169047 ENSG00000140443 PMC8106283__F1 Preventive Role of Cannabinoids Derivate against Methylphenidate-Induced Oxidative Stress and Inflammation: The Hypothetical Function of Keap1/Nrf2/ARE Signaling and Proposal of a Treatment Strategy for Neurodegeneration ENSG00000002330 ENSG00000125538 ENSG00000079999 PMC6215878__F6 Diminished inhibin B (INHBB) expression activates the transforming growth factor‐B (TGF‐B) pathway to promote anoikis resistance and migration ENSG00000163083 PMC4923650__F1 Integration of RDGN with TGFB to regulate EMT ENSG00000170365 ENSG00000169554 ENSG00000276644 ENSG00000064655 ENSG00000126778 PMC3915289__F1 The kynurenine metabolic pathway ENSG00000162882 ENSG00000125538 PMC7391499__F5 Lignin biosynthesis pathway and monolignol biosynthesis related gene expression in P ENSG00000112977 ENSG00000084774 PMC9684248__F7 Pyroptosis in inflammation-related respiratory disease ENSG00000278718 ENSG00000168610 ENSG00000147697 PMC9684248__F8 Pyroptosis in inflammation-related respiratory disease ENSG00000162711 ENSG00000163568 ENSG00000265972 PMC3510826__F8 Important roles of SFKs in G protein-coupled receptor-induced platelet activation ENSG00000166278 PMC5337359__F1 Interactions between the canonical Wnt/beta-catenin pathway and PPAR gamma under aerobic glycolysis conditions in colon cancer ENSG00000108582 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9684248__F1 Pyroptosis in inflammation-related respiratory disease ENSG00000278718 ENSG00000162711 ENSG00000150782 ENSG00000170458 ENSG00000189403 ENSG00000172936 ENSG00000265972 PMC9684248__F2 Pyroptosis in inflammation-related respiratory disease ENSG00000278718 ENSG00000167914 ENSG00000147697 ENSG00000073605 PMC3202104__F2 EBV infection impacts on cell death and survival pathways in GC B cells ENSG00000100290 ENSG00000186716 ENSG00000168040 ENSG00000026103 PMC9684248__F5 Pyroptosis in inflammation-related respiratory disease ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000136869 PMC9684248__F6 Pyroptosis in inflammation-related respiratory disease ENSG00000278718 ENSG00000162711 ENSG00000091592 ENSG00000136869 PMC9684248__F3 Pyroptosis in inflammation-related respiratory disease ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000136869 ENSG00000073605 PMC9684248__F4 Pyroptosis in inflammation-related respiratory disease ENSG00000278718 ENSG00000162711 ENSG00000265972 ENSG00000062485 PMC7921316__F3 Molecular mechanisms of natural polyphenols in colon cancer ENSG00000125538 ENSG00000168036 ENSG00000168040 PMC10534731__F2 Possible Mechanisms of Dark Tea in Cancer Prevention and Management: A Comprehensive Review ENSG00000086991 ENSG00000172936 PMC8511501__F6 Polydatin Ameliorates Osteoporosis via Suppression of the Mitogen-Activated Protein Kinase Signaling Pathway ENSG00000077150 ENSG00000169032 ENSG00000196396 ENSG00000179295 PMC12110172__F1 Hippo-YAP pathway ENSG00000150457 ENSG00000131023 PMC12157585__F1 C. elegans fatty acid synthesis pathway and FAT-2 desaturase ENSG00000083857 ENSG00000165323 PMC8570281__F1 Genetic Polymorphisms in High-Dose Methotrexate Toxicity and Response in Hematological Malignancies: A Systematic Review and Meta-Analysis ENSG00000228716 ENSG00000173638 ENSG00000136877 ENSG00000137563 PMC8343371__F1 Coronavirus disease-2019: A review on the disease exacerbation via cytokine storm and concurrent management ENSG00000130234 ENSG00000184012 PMC8318774__F12 Huotan Jiedu Tongluo Decoction Inhibits Balloon-Injury-Induced Carotid Artery Intimal Hyperplasia in the Rat through the PERK-eIF2Alpha-ATF4 Pathway and Autophagy Mediation ENSG00000128272 ENSG00000145782 PMC3969039__F2 Putative model of the mechanism of vascular homeostasis mediated by apelin-APJ signaling ENSG00000171759 ENSG00000127528 ENSG00000077782 PMC8732267__F1 Signaling pathways regulated by GA12/13 in solid tumors ENSG00000070831 ENSG00000163914 ENSG00000198670 ENSG00000150457 ENSG00000168610 ENSG00000131023 PMC4180627__F1 The endocrinology of vitamin D ENSG00000118972 ENSG00000152266 ENSG00000105516 ENSG00000019186 ENSG00000036828 PMC3103347__F5 Effect of SCGB3A2 on TGFB signaling pathway ENSG00000157933 ENSG00000005339 ENSG00000138798 ENSG00000183691 ENSG00000134363 ENSG00000020633 ENSG00000168610 ENSG00000136603 ENSG00000170365 ENSG00000160973 ENSG00000111537 ENSG00000069482 ENSG00000118785 ENSG00000095739 ENSG00000177606 ENSG00000128342 PMC10750283__F4 Nuclear Receptors in the Pathogenesis and Treatment of Non-alcoholic Fatty Liver Disease ENSG00000160867 ENSG00000167910 ENSG00000134324 ENSG00000062282 PMC2623309__F1 Multiple feedback loops of p53 pathway ENSG00000113328 ENSG00000168036 ENSG00000123374 ENSG00000196470 PMC7422534__F4 MicroRNA-target interaction networks ENSG00000118972 ENSG00000172380 ENSG00000149930 ENSG00000135090 ENSG00000120875 ENSG00000181104 ENSG00000166862 ENSG00000150093 ENSG00000164399 ENSG00000099942 ENSG00000102678 ENSG00000100346 ENSG00000164305 ENSG00000068971 ENSG00000160691 ENSG00000068028 ENSG00000185652 ENSG00000150630 PMC2874322__F4 An Update on the Genetics of Atopic Dermatitis: Scratching the Surface in 2009 ENSG00000178096 ENSG00000162711 ENSG00000142192 ENSG00000167207 ENSG00000232326 ENSG00000091106 ENSG00000239732 ENSG00000102970 ENSG00000142405 ENSG00000131724 ENSG00000168310 ENSG00000198125 ENSG00000139687 ENSG00000104081 PMC2874322__F5 An Update on the Genetics of Atopic Dermatitis: Scratching the Surface in 2009 ENSG00000284881 ENSG00000167207 ENSG00000159516 ENSG00000163209 ENSG00000244094 ENSG00000196805 ENSG00000203785 ENSG00000145777 ENSG00000106100 ENSG00000143631 ENSG00000241794 ENSG00000169469 ENSG00000170458 ENSG00000163207 ENSG00000169474 ENSG00000168310 PMC8615888__F1 STING Signaling and Skin Cancers ENSG00000164430 ENSG00000160703 PMC8341640__F2 Critical Role of PARPs in Regulating Innate Immune Responses ENSG00000183735 ENSG00000117020 ENSG00000276561 ENSG00000106546 PMC4433321__F8 Hypothetical involvement of glucokinase (GK) and therefore glucokinase activators (GKAs) in the preservation and growth promotion of pancreatic Beta-cells ENSG00000002330 ENSG00000139515 PMC8341640__F3 Critical Role of PARPs in Regulating Innate Immune Responses ENSG00000143799 ENSG00000059378 ENSG00000189403 ENSG00000172936 ENSG00000178685 PMC10999489__F2 Personalized treatment concepts in extraocular cancer ENSG00000128602 PMC3725690__F6 Working model for the NOX dependence of TNFA production by the liver following I/R injury PMC11212700__F1 From macroautophagy to mitophagy: Unveiling the hidden role of mitophagy in gastrointestinal disorders ENSG00000090432 ENSG00000215021 ENSG00000183735 ENSG00000166233 ENSG00000123240 ENSG00000291971 ENSG00000158828 ENSG00000069509 ENSG00000247077 PMC11212700__F2 From macroautophagy to mitophagy: Unveiling the hidden role of mitophagy in gastrointestinal disorders ENSG00000177169 ENSG00000162711 ENSG00000239732 ENSG00000116688 ENSG00000158828 ENSG00000166073 ENSG00000096717 ENSG00000087460 PMC8341640__F1 Critical Role of PARPs in Regulating Innate Immune Responses ENSG00000143799 ENSG00000183735 ENSG00000164430 ENSG00000291803 ENSG00000041880 ENSG00000138385 PMC4174596__F1 Hh pathway response in vertebrates ENSG00000102312 ENSG00000128602 PMC4918286__F1 Hippo pathway signaling in Drosophila and mammals.Note: (A) Signaling diagram ENSG00000129474 ENSG00000186575 ENSG00000142192 ENSG00000109321 ENSG00000089685 ENSG00000135903 ENSG00000153303 ENSG00000150457 ENSG00000169435 ENSG00000089225 PMC6110482__F6 Exposure to nicotine-derived nitrosamine ketone and arecoline synergistically facilitates tumor aggressiveness via overexpression of epidermal growth factor receptor and its downstream signaling in head and neck squamous cell carcinoma ENSG00000146648 PMC7756113__F3 Mechanism of autophagy ENSG00000198793 ENSG00000284099 ENSG00000057663 PMC6637043__F9 Schematic diagram showing the proposed signalling pathways for inflammatory and autoimmunity‐associated gene expression via Ca2+ and Ca2+‐dependent/‐binding proteins ENSG00000070193 ENSG00000172936 ENSG00000168610 PMC9599458__F3 Calcium-Permeable Channels Cooperation for Rheumatoid Arthritis: Therapeutic Opportunities ENSG00000198793 ENSG00000086991 PMC6563119__F1 Canonical and alternative Hippo pathways ENSG00000123728 ENSG00000197905 ENSG00000114978 ENSG00000168067 ENSG00000181467 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 ENSG00000125249 ENSG00000104814 ENSG00000117525 ENSG00000011566 ENSG00000150907 PMC4226164__F1 Damage-associated molecular pattern signaling mechanisms ENSG00000162711 ENSG00000070831 ENSG00000125538 ENSG00000172936 ENSG00000166278 PMC3103347__F7 Schematic diagram for the SCGB3A2-induced inhibition of the TGFB signaling pathway ENSG00000111537 ENSG00000115415 PMC5836099__F5 Mitotic arrest and slippage in inflammation and immunity ENSG00000164430 ENSG00000177595 ENSG00000117399 ENSG00000254550 PMC6563119__F5 Dual functions of the cancer cell-intrinsic Hippo pathway in immune modulation ENSG00000108691 ENSG00000081041 ENSG00000163739 ENSG00000197905 ENSG00000184371 ENSG00000007866 ENSG00000150457 ENSG00000125347 ENSG00000131023 ENSG00000074219 PMC3670510__F1 Targetable metabolic actors by natural compounds ENSG00000115263 ENSG00000159399 ENSG00000026103 PMC5357299__F8 Schematic overview of the proposed iOGN:TLR4 signaling pathway ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC6563119__F4 Roles of the Hippo pathway in effector T cell differentiation ENSG00000111537 ENSG00000134982 ENSG00000049768 PMC10243112__F7 Machine Learning Reveals Lipidome Remodeling Dynamics in a Mouse Model of Ovarian Cancer ENSG00000039537 ENSG00000042832 ENSG00000173599 ENSG00000166278 PMC2679172__F1 Crosstalk at the initial encounter: Interplay between host defense and ameba survival strategies ENSG00000069482 ENSG00000166278 PMC2756331__F1 Trk receptor tyrosine kinases and major signal transduction pathways ENSG00000002330 ENSG00000070831 ENSG00000163914 ENSG00000105723 PMC4123471__F6 Extracellular Matrix and Liver Disease ENSG00000101146 ENSG00000171791 PMC4229247__F4 Pathways for initiation and maintenance of psoriasis ENSG00000239732 PMC4760771__F7 HIV-Tat Induces the Nrf2/ARE Pathway through NMDA Receptor-Elicited Spermine Oxidase Activation in Human Neuroblastoma Cells ENSG00000128602 PMC8268646__F1 From Messengers to Receptors in Psoriasis: The Role of IL-17RA in Disease and Treatment ENSG00000166090 ENSG00000056736 ENSG00000175104 ENSG00000127191 ENSG00000177663 ENSG00000163702 PMC9280173__F9 Antiproliferative and apoptotic potential of Glycyrrhizin against HPV16+ Caski cervical cancer cells: A plausible association with downreguation of HPV E6 and E7 oncogenes and Notch signaling pathway ENSG00000002330 ENSG00000135446 PMC2783351__F2 “Toll” of Opioid-Induced Glial Activation: Improving the Clinical Efficacy of Opioids by Targeting Glia ENSG00000170458 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC5372728__F2 Effect of chronic alcohol intake on mammalian/mechanistic target of rapamycin complex 1 (mTORC1) signaling in white adipose tissue from mice ENSG00000284161 PMC5372728__F1 Lipolytic and lipogenic pathways in white adipose tissue ENSG00000135218 ENSG00000169710 PMC8999811__F1 Jasmonate Signaling Pathway Modulates Plant Defense, Growth, and Their Trade-Offs ENSG00000136997 ENSG00000104973 PMC8999811__F2 Jasmonate Signaling Pathway Modulates Plant Defense, Growth, and Their Trade-Offs ENSG00000136997 ENSG00000104973 PMC6750278__F1 Diagram illustrating damage processes and pathways thought to contribute to HC loss due to acoustic overexposure ENSG00000070831 ENSG00000291971 ENSG00000177606 PMC4566117__F4 Surfactant metabolism ENSG00000245848 ENSG00000173599 ENSG00000167972 ENSG00000168878 ENSG00000168484 ENSG00000136352 ENSG00000157765 PMC8999811__F4 Jasmonate Signaling Pathway Modulates Plant Defense, Growth, and Their Trade-Offs ENSG00000108582 ENSG00000110934 ENSG00000042088 PMC5987207__F1A Systems and synthetic biology approaches in understanding biological oscillators ENSG00000144063 ENSG00000134982 ENSG00000172005 PMC8025964__F6 Summary of SEPT6-regulated Hippo/YAP signaling pathway in HCC ENSG00000087245 ENSG00000131023 PMC6750865__F1 Possible integrated mechanism of cell injury and its relationship with microcephaly ZIKV-induced and cell death ENSG00000162711 ENSG00000124256 ENSG00000137275 ENSG00000137033 ENSG00000163568 ENSG00000198793 ENSG00000125347 ENSG00000285379 PMC6077295__F2 Serrated neoplasia pathway as an alternative route of colorectal cancer carcinogenesis ENSG00000157764 ENSG00000170430 ENSG00000163453 PMC3954160__F1 Insulin signaling pathway ENSG00000104812 ENSG00000262785 ENSG00000171105 ENSG00000002330 ENSG00000100994 ENSG00000288174 ENSG00000198793 ENSG00000169710 ENSG00000169885 ENSG00000142273 ENSG00000163558 ENSG00000079435 ENSG00000180008 PMC6581573__F2 Stylized diagram showing the synthesis, degradation, release and uptake of monoamines, synaptic effectors and targets of methylphenidate ENSG00000276825 ENSG00000150594 ENSG00000184845 ENSG00000169676 ENSG00000139287 ENSG00000103546 ENSG00000123454 ENSG00000165646 ENSG00000276996 ENSG00000149295 PMC7008497__F3 Signals 1 and 2 for nod‐like receptor protein 3 (NLRP3) activation may be delivered by cGAS or TLR9 ENSG00000239732 ENSG00000164430 ENSG00000125538 PMC3047110__F6 Proposed model for ERG functions in prostaglandin signaling pathway ENSG00000157554 ENSG00000166278 ENSG00000164120 PMC316535__F6 Genetic models for ptp-2 signaling during (A) oogenesis and (B) vulval development ENSG00000138798 ENSG00000146648 PMC4638384__F2 Regulation of the Hippo pathway in Drosophila ENSG00000132471 PMC4638384__F3 Regulation of the Hippo pathway in mammals ENSG00000132471 ENSG00000126016 ENSG00000186575 ENSG00000181788 ENSG00000163914 ENSG00000196470 ENSG00000150457 ENSG00000131023 PMC8576247__F4 Clinical values and potential pathways of miR-183-5p in gastric cancer: a study based on integrational bioinformatics analysis ENSG00000163637 ENSG00000105664 ENSG00000112964 ENSG00000169862 ENSG00000189056 ENSG00000198793 ENSG00000157445 ENSG00000134245 ENSG00000188153 ENSG00000064300 PMC8247090__F4 Exposure to ethanol leads to midfacial hypoplasia in a zebrafish model of FASD via indirect interactions with the Shh pathway ENSG00000151657 ENSG00000117425 ENSG00000171791 PMC6639958__F8 Proposed model of MEK as a key regulatory pathway of the IFN response against RV and RSV in airway epithelial cells ENSG00000168610 ENSG00000146648 ENSG00000164342 ENSG00000142166 PMC4638384__F1 Inhibition of YAP/TAZ transcriptional coactivators by LATS1/2 ENSG00000144560 ENSG00000197905 ENSG00000007866 ENSG00000131023 ENSG00000074219 PMC4638384__F4 Therapeutic targeting of the Hippo pathway ENSG00000163914 ENSG00000197905 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC10418941__F2 Molecular crosslinks produced by the interaction of the HSCs and LSCs ENSG00000170558 ENSG00000136826 PMC3773501__F1 NOD2, an Intracellular Innate Immune Sensor Involved in Host Defense and Crohn's Disease ENSG00000088888 ENSG00000167207 ENSG00000137265 PMC5495050__F3 BRD4 pathway in acute myeloid leukemia (AML) cells ENSG00000151702 ENSG00000157554 ENSG00000141867 ENSG00000136997 ENSG00000167074 ENSG00000147548 ENSG00000105810 ENSG00000100888 PMC10418941__F3 LSCs’ microenvironment in relation to epigenetic modification ENSG00000081237 ENSG00000136997 ENSG00000129226 ENSG00000026508 ENSG00000136869 ENSG00000112715 ENSG00000102974 PMC10418941__F4 LSCs mechanism that employs fat as fuel ENSG00000275565 PMC7933526__F10 Mechanism underlying renal-protective effect of QYDP ENSG00000168036 PMC8504268__F1 Lys694Arg polymorphism leads to blunted responses to LPS by interfering TLR4 with recruitment of MyD88 ENSG00000170458 ENSG00000125538 ENSG00000172936 ENSG00000150455 PMC8475840__F1 Metabolic reprogramming and metabolic sensors in KSHV-induced cancers and KSHV infection ENSG00000269858 ENSG00000159399 PMC5442467__F8 Summary of the impact of keratins on the Notch1 signalling pathway ENSG00000135547 ENSG00000148400 PMC3855091__F6 Foxa2 deletion leading to premature aging and age-onset obesity ENSG00000168209 ENSG00000149212 ENSG00000101255 ENSG00000173757 ENSG00000198793 PMC8834130__F1 Oral Immune-Related Adverse Events Caused by Immune Checkpoint Inhibitors: Salivary Gland Dysfunction and Mucosal Diseases ENSG00000186716 ENSG00000173599 ENSG00000145321 PMC4464753__F7 Long-Term Mild, rather than Intense, Exercise Enhances Adult Hippocampal Neurogenesis and Greatly Changes the Transcriptomic Profile of the Hippocampus ENSG00000125538 ENSG00000169047 ENSG00000140443 PMC2837572__F2 An overview of the signalling pathways mediated by TNFA in metastasis ENSG00000168036 PMC9562907__F1 Complement in nonalcoholic fatty liver disease ENSG00000288512 ENSG00000166278 ENSG00000182326 PMC2837572__F1 Downstream signalling pathways of TNFA ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC6601209__F1 Graphic depiction of the gene engineering strategy and glycoproteomics workflow ENSG00000130035 ENSG00000119514 ENSG00000288490 ENSG00000164574 ENSG00000115339 ENSG00000257594 ENSG00000109586 ENSG00000136542 PMC4601184__F1 IGFR1, a possible target in tumor progression and metastasis ENSG00000087245 ENSG00000138798 ENSG00000100985 ENSG00000146648 PMC6073226__F4 Mechanism of modulation on sphingolipids by chrysin (A), curcumin (B) and genistein (C) ENSG00000063176 ENSG00000102172 PMC7469703__F5 CSHMM predicts the precise timing of Wnt modulation as a determinant of cell fate ENSG00000156076 ENSG00000168646 ENSG00000140807 PMC3749695__F8 Cumulative scheme adapted from the data published in (, –, , , , , ) showing components of pathways implicated in regulating the life span in Drosophila and their interactions ENSG00000105227 ENSG00000079999 PMC10750282__F2 CGAS-STING Signalling in Metabolic Diseases: from Signalling Networks to Targeted Intervention ENSG00000278718 ENSG00000006071 ENSG00000183735 ENSG00000108691 ENSG00000164430 ENSG00000136869 ENSG00000155659 ENSG00000100985 ENSG00000162692 ENSG00000127191 ENSG00000131023 ENSG00000164342 PMC8802753__F3 Polyphenols and omega-3 PUFAs: Beneficial Outcomes to Obesity and Its Related Metabolic Diseases PMC6852943__F2 Inhibitory effect of miRNAs on their target molecules in the UPS pathway ENSG00000036672 ENSG00000077721 ENSG00000119048 PMC7786163__F2 Links among COVID-19, cytokine storms, and HF ENSG00000108691 ENSG00000115415 ENSG00000125538 PMC10750282__F3 CGAS-STING Signalling in Metabolic Diseases: from Signalling Networks to Targeted Intervention ENSG00000177169 ENSG00000162711 ENSG00000163568 ENSG00000198793 ENSG00000169047 ENSG00000142166 ENSG00000183735 ENSG00000164430 ENSG00000284099 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 PMC6505634__F3 MEF-2 isoforms' (A-D) roles in development and tumorigenesis ENSG00000198793 ENSG00000120729 PMC7796017__F2 PI3K/AKT/mTOR signaling pathway and breast cancer ENSG00000077782 ENSG00000146648 ENSG00000140443 PMC4593004__F2 Genetic variants in PLCB4/PLCB1 as susceptibility loci for coronary artery aneurysm formation in Kawasaki disease in Han Chinese in Taiwan ENSG00000164736 ENSG00000112685 ENSG00000184347 ENSG00000185760 ENSG00000127124 ENSG00000086015 ENSG00000170293 ENSG00000156011 ENSG00000101333 ENSG00000168118 PMC10882078__F7 TNF signaling pathway in atherosclerosis-related and non-related to CKD ENSG00000078747 ENSG00000102871 ENSG00000131323 ENSG00000168040 ENSG00000127191 PMC7564975__F2 Different ratios of STAT3A/STAT3B and their functions in therapy sensitivity ENSG00000291971 ENSG00000168610 ENSG00000146648 PMC4618389__F1 Vulture-specific genetic change in immune system ENSG00000167207 ENSG00000170458 ENSG00000106100 ENSG00000276561 PMC5088527__F7 Linking the circadian clock with the NAD+ salvage pathway ENSG00000105835 ENSG00000096717 PMC9005797__F1 Holistic Approach to Immune Checkpoint Inhibitor-Related Adverse Events ENSG00000134982 PMC3594751__F7 Schematic view of the roles of S-PCNA and Srs2 in the rescue of stalled replication forks ENSG00000132646 ENSG00000070950 ENSG00000130997 ENSG00000051180 ENSG00000122678 PMC7544739__F2 Interactive roles of SOCS1 and SOCS3 in TLR signaling ENSG00000183735 ENSG00000157933 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC5088527__F2 Biosynthesis pathways of acetyl-CoA and NAD cofactors, and their involvement in chromatin-related processes ENSG00000105835 ENSG00000205221 ENSG00000096717 PMC4511319__F4 Signaling network of endothelin axis (ET) and micro ribonucleic acid (miRNA)-200, the ET axis can be influenced by miRNA-200c on different pathways (red arrows: induction of pathway; black arrows: blockade of pathway) ENSG00000169554 PMC6731444__F8 A scheme for DMF induced SOCS3/JAK1/STAT3 signaling pathway in HCC cells ENSG00000112715 ENSG00000168610 ENSG00000057663 PMC7145703__F4 Evolutionary Basis of High-Frequency Hearing in the Cochleae of Echolocators Revealed by Comparative Genomics ENSG00000095585 ENSG00000213928 ENSG00000033327 ENSG00000184995 ENSG00000115415 ENSG00000083799 ENSG00000131196 ENSG00000143387 PMC3721332__F2 Interactions between nTreg (A) or IL-2 activated inducible Treg (Tr1) with effector T cells (Teff) mediated by the adenosine and PGE2 pathways ENSG00000049768 PMC4516433__F5 Cerebral nitric oxide represses choroid plexus NFKB-dependent gateway activity for leukocyte trafficking ENSG00000169245 ENSG00000108691 ENSG00000111537 ENSG00000127191 PMC10215584__F5 PPI network analysis according to STRING database and KEGG pathway enriched in DEPs in the groups of (A) MRC vs ENSG00000134042 ENSG00000166501 ENSG00000291748 ENSG00000167676 ENSG00000091138 ENSG00000109323 ENSG00000117305 PMC7145703__F5 Evolutionary Basis of High-Frequency Hearing in the Cochleae of Echolocators Revealed by Comparative Genomics ENSG00000143799 ENSG00000242689 ENSG00000102871 ENSG00000138798 ENSG00000163064 ENSG00000111321 ENSG00000150455 ENSG00000095585 ENSG00000149311 ENSG00000226275 ENSG00000213658 ENSG00000170458 ENSG00000186716 ENSG00000125538 ENSG00000197943 ENSG00000136869 ENSG00000124181 ENSG00000162692 PMC5938338__F7 Schematic of Ca2+signaling pathway activated by alkaline stimuli to dentin surface and PLC-coupled receptor activation in odontoblasts ENSG00000104321 PMC7915495__F3 Protective effects of small-molecule natural products on OS in CKD ENSG00000157554 ENSG00000175793 ENSG00000096717 ENSG00000142082 PMC4911704__F1 MTOR in maintenance of glomerular epithelial cells ENSG00000177169 ENSG00000145979 ENSG00000118515 PMC9504399__F3 Feedback Regulation of Signaling Pathways for Precise Pre-Placodal Ectoderm Formation in Vertebrate Embryos ENSG00000170365 ENSG00000137834 ENSG00000095739 ENSG00000198742 PMC9504399__F4 Feedback Regulation of Signaling Pathways for Precise Pre-Placodal Ectoderm Formation in Vertebrate Embryos ENSG00000011201 ENSG00000125848 ENSG00000170549 ENSG00000183145 PMC5949255__F3 Deciphering p53 Signaling in Tumor Suppression ENSG00000177169 ENSG00000152348 ENSG00000198382 ENSG00000151012 ENSG00000083290 ENSG00000088305 ENSG00000066739 ENSG00000122786 ENSG00000137801 ENSG00000138336 ENSG00000134574 ENSG00000163914 ENSG00000284194 ENSG00000095002 PMC7391449__F1 Cellular Oxygen Sensors ENSG00000072274 ENSG00000159399 PMC5797050__F3 Identifying characteristic miRNAs-genes and risk pathways of multiple sclerosis based on bioinformatics analysis ENSG00000112977 ENSG00000162600 PMC5797050__F4 Identifying characteristic miRNAs-genes and risk pathways of multiple sclerosis based on bioinformatics analysis ENSG00000170458 ENSG00000117400 ENSG00000177606 ENSG00000149308 ENSG00000130159 ENSG00000026103 PMC10866657__F2 BMP9-10/ENG/ALK1/SMAD4 signaling pathway maintains vascular quiescence by repressing angiogenic pathways ENSG00000170365 ENSG00000135446 ENSG00000118515 ENSG00000105810 ENSG00000112715 ENSG00000163217 PMC5858934__F4 Model for RHO/ROCK-dependent regulation of trophectoderm-lineage specification ENSG00000126016 ENSG00000186575 ENSG00000163914 PMC4303468__F18 Generation and metabolism of H2S PMC4060729__F2 Flowchart showing the induction of ER stress and its physiological outcomes during coronavirus infection ENSG00000144895 ENSG00000100219 PMC6667284__F1 Intracellular interactions and fates of microbes opsonized with C3 in the extracellular milieu ENSG00000088888 PMC8711024__F7 Zoledronic acid inhibits osteoclastogenesis and bone resorptive function by suppressing RANKL-mediated NFKB and JNK and their downstream signalling pathways ENSG00000164935 ENSG00000175104 ENSG00000131196 PMC9247874__F3 Long Non-coding RNAs With In Vitro and In Vivo Efficacy in Preclinical Models of Esophageal Squamous Cell Carcinoma Which Act by a Non-microRNA Sponging Mechanism ENSG00000149311 ENSG00000101945 ENSG00000042832 ENSG00000116717 ENSG00000205250 ENSG00000187678 PMC3352318__F7 Association of mitochondrial peptidyl Cys with functional networks according to reduction and oxidation of Cys residues ENSG00000050730 ENSG00000283887 ENSG00000140740 ENSG00000105329 ENSG00000073578 ENSG00000117118 ENSG00000138798 ENSG00000112715 ENSG00000127884 ENSG00000117054 ENSG00000164405 ENSG00000263528 ENSG00000173599 ENSG00000146701 ENSG00000125166 ENSG00000169021 ENSG00000100906 ENSG00000179091 ENSG00000156467 ENSG00000008394 ENSG00000010256 ENSG00000004779 ENSG00000138160 ENSG00000130304 ENSG00000233954 ENSG00000143252 ENSG00000115946 ENSG00000285121 ENSG00000184076 ENSG00000119013 ENSG00000105379 PMC7827005__F1 Activation of signaling pathways (selected) in MM cells in the BM microenvironment ENSG00000104856 ENSG00000154342 ENSG00000002330 ENSG00000198793 ENSG00000136997 ENSG00000168610 PMC7827005__F2 Cell adhesion-induced activation of signaling pathways ENSG00000171791 ENSG00000162692 PMC6134795__F1 Composite pathway using the KEGG pathway analysis, a composite pathway was generated based on the canonical mapping of the phosphorylated proteins independently associated with increased % collagen (red) in the liver ENSG00000106683 ENSG00000127191 ENSG00000182541 ENSG00000026103 PMC5636987__F6 Proposed working model: POPX2 regulates the TAK1-IKK-NFKB pathway during DNA-damage-induced apoptosis ENSG00000149311 ENSG00000157625 ENSG00000175104 PMC6544937__F5 miR-15/107 family targeted genes in cell cycle KEGG pathway calculated by miRPath v3.0 web-server ENSG00000005339 ENSG00000132646 ENSG00000123374 ENSG00000164754 ENSG00000162924 ENSG00000277273 ENSG00000253729 PMC3352318__F6 Association of nuclear peptidyl Cys with functional networks according to reduction and oxidation of Cys residues ENSG00000169371 ENSG00000291971 ENSG00000153037 ENSG00000125676 ENSG00000197451 ENSG00000101654 ENSG00000126254 ENSG00000124795 ENSG00000084463 ENSG00000184575 ENSG00000253729 ENSG00000165119 ENSG00000108349 ENSG00000136938 ENSG00000063244 ENSG00000162385 ENSG00000122566 ENSG00000288485 ENSG00000132661 ENSG00000168066 ENSG00000112232 ENSG00000141480 ENSG00000132646 ENSG00000054118 ENSG00000132341 PMC12102218__F8 Diagram illustrating the mechanism through which ISM5939 potentiates antitumor immune responses ENSG00000164430 ENSG00000197594 PMC3352318__F4 Association of cytoplasmic peptidyl Cys with functional networks according to reduction and oxidation of Cys residues ENSG00000115484 ENSG00000163399 ENSG00000130741 ENSG00000196975 ENSG00000198755 ENSG00000119888 ENSG00000134308 ENSG00000198648 ENSG00000178209 ENSG00000111530 ENSG00000090621 ENSG00000169710 ENSG00000167552 ENSG00000105568 ENSG00000135624 ENSG00000149273 ENSG00000283391 ENSG00000197879 ENSG00000130402 ENSG00000106305 ENSG00000141367 ENSG00000136068 PMC7736605__F1 Autophagy influence on tumor-associated antigen presentation 1 PMC6329627__F1 PG biosynthesis, receptors and signalling pathways ENSG00000163914 PMC2567408__F8 NCAM upregulation leads to a functional switch ENSG00000169291 ENSG00000010810 PMC3302445__F7 How BRG1 and CHD4 antagonistically influence Wnt signaling during yolk sac vascular development ENSG00000168036 ENSG00000111642 PMC6329627__F2 Lymphocyte‐mediated chronic inflammatory responses ENSG00000137033 ENSG00000145777 ENSG00000166090 PMC5850516__F1 Transforming growth factor B activated kinase 1: a potential therapeutic target for rheumatic diseases ENSG00000187554 ENSG00000082512 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC6329627__F3 Molecular mechanisms for PGE2‐cytokine crosstalk in facilitation of adaptive Th1 and Th17 cell responses ENSG00000162594 ENSG00000168610 ENSG00000160741 PMC4926172__F1 Schematic overview of viruses that subvert the PI3K/Akt/mTOR signaling pathway ENSG00000198793 ENSG00000150093 PMC4926172__F2 Downstream targets of mTORC1 ENSG00000163435 ENSG00000198793 PMC8328766__F3 Astrocytes: a double-edged sword in neurodegenerative diseases ENSG00000198793 ENSG00000163914 ENSG00000168610 PMC8910224__F4 Micro-Current Stimulation Suppresses Inflammatory Responses in Peptidoglycan-Treated Raw 264.7 Macrophages and Propionibacterium acnes-Induced Skin Inflammation via TLR2/NFKB Signaling Pathway ENSG00000172936 ENSG00000175104 PMC8278373__F2 Therapeutic approaches targeting the GFB in clinical or late preclinical development ENSG00000070831 ENSG00000137672 ENSG00000072315 PMC11757730__F7 Anti-inflammatory effects of chamuangone in lipopolysaccharide-induced murine (Mus musculus) RAW264 ENSG00000172936 ENSG00000136869 PMC3855406__F2 Signaling pathways of NFKB activation ENSG00000102871 ENSG00000111321 ENSG00000168040 ENSG00000175104 PMC8678573__F3 Lipid Droplets, the Central Hub Integrating Cell Metabolism and the Immune System ENSG00000010810 ENSG00000173599 PMC7658535__F7 Signaling pathways induced by prolonged exposure to H ENSG00000104365 ENSG00000110330 ENSG00000099860 ENSG00000145782 ENSG00000106100 ENSG00000184481 PMC8306561__F3 Autophagy Inhibition in BRAF-Driven Cancers ENSG00000177169 ENSG00000128272 ENSG00000157764 ENSG00000144895 ENSG00000112561 PMC5003635__F3 Oridonin regulates multi-signaling pathways to display corresponding multifunctional effects ENSG00000120868 ENSG00000079999 PMC8306561__F2 Autophagy Inhibition in BRAF-Driven Cancers ENSG00000152348 ENSG00000123395 ENSG00000126775 ENSG00000144848 ENSG00000057663 PMC7710892__F3 The CoQ10 biosynthesis pathway ENSG00000132423 ENSG00000123815 ENSG00000119723 ENSG00000163050 ENSG00000110871 ENSG00000088682 ENSG00000148459 ENSG00000173085 ENSG00000167186 PMC3980962__F1 Origins and implications of pluripotent stem cell variability and heterogeneity ENSG00000043355 ENSG00000170365 ENSG00000103479 ENSG00000115507 ENSG00000135111 ENSG00000205927 ENSG00000128342 ENSG00000168610 ENSG00000110693 PMC11064142__F8 A) Interaction of mir15a/16-5p cluster and mir-7641 with targeted genes involved in intrinsic and extrinsic signalling pathways of apoptosis ENSG00000165891 ENSG00000153094 ENSG00000132646 ENSG00000177606 ENSG00000136997 ENSG00000137076 ENSG00000171791 ENSG00000112715 PMC3744446__F1 Past Visits Present: TCF/LEFs Partner with ATFs for Beta-Catenin–Independent Activity ENSG00000138795 ENSG00000168036 ENSG00000196628 PMC7275976__F1 SARS-CoV2 replication cycle and potential targets of CQ/HCQ ENSG00000130234 PMC7838196__F10 AGE-RAGE signaling pathway in diabetic complications ENSG00000007908 PMC8475840__F4 Metabolic reprogramming and metabolic sensors in KSHV-induced cancers and KSHV infection ENSG00000239282 ENSG00000096717 PMC2858431__F1 Developing Antiepileptogenic Drugs for Acquired Epilepsy: Targeting the Mammalian Target of Rapamycin (mTOR) Pathway ENSG00000198793 PMC9022965__F2 Four enzymatic pathways that drive PL remodelling ENSG00000174348 ENSG00000173599 PMC5896114__F4 Location of si:ch211-167b20.8, socs9, eif4e1c and CALML6 in the insulin signaling pathway ENSG00000171105 ENSG00000002330 ENSG00000110395 ENSG00000102034 ENSG00000150907 ENSG00000198793 ENSG00000026103 PMC3755284__F1 Ligand modified nanoparticles increases cell uptake, alters endocytosis and elevates glioma distribution and internalization ENSG00000039537 ENSG00000123496 ENSG00000214285 ENSG00000188158 PMC3159114__F1 Modulation of cellular reactive oxygen species (ROS) ENSG00000086991 ENSG00000105227 PMC8573605__F1 Defining the structure of the NF-ĸB pathway in human immune cells using quantitative proteomic data ENSG00000104856 ENSG00000173039 PMC4762627__F4 NFE2L2-Regulated Antioxidant Response in Activated Microglia ENSG00000166794 ENSG00000065833 ENSG00000284099 ENSG00000167996 ENSG00000165280 ENSG00000125656 ENSG00000023909 ENSG00000082212 ENSG00000135624 ENSG00000101557 PMC12203236__F2 Targeting Molecular Pathways in Breast Cancer Using Plant-Derived Bioactive Compounds: A Comprehensive Review ENSG00000145604 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC9506445__F1 Association of Homologous Recombination–DNA Damage Response Gene Mutations with Immune Biomarkers in Gastroesophageal Cancers ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000083093 ENSG00000144554 ENSG00000051180 ENSG00000139618 ENSG00000183765 PMC7802183__F7 As a biomarker for gastric cancer, circPTPN22 regulates the progression of gastric cancer through the EMT pathway ENSG00000162630 ENSG00000162433 ENSG00000185305 ENSG00000183918 ENSG00000149929 ENSG00000114859 ENSG00000143858 ENSG00000166136 ENSG00000121406 ENSG00000157927 ENSG00000157500 ENSG00000139515 ENSG00000157064 ENSG00000145850 ENSG00000214042 ENSG00000280548 ENSG00000172380 ENSG00000117152 ENSG00000234829 ENSG00000139574 ENSG00000137100 ENSG00000285318 ENSG00000187510 ENSG00000149635 ENSG00000214300 ENSG00000196092 ENSG00000274391 ENSG00000204363 ENSG00000197106 ENSG00000133477 ENSG00000253537 ENSG00000141642 ENSG00000111224 PMC3164150__F1 The insulin receptor (IR) with its two subtypes IR-A and IR-B, the insulin growth factor 1 receptor (IGF-IR) and the hybrid receptors (IGF-1R/IR-A and IGF-1R/IR-B) ENSG00000140443 PMC7603197__F1 Aberrant FGF/FGFR signaling in breast cancer ENSG00000142192 ENSG00000110395 PMC3164150__F2 Insulin-like growth factor 1 receptor (IGF-1R) signaling pathway ENSG00000002330 ENSG00000169047 ENSG00000198793 PMC4940047__F2 Regulation of hepcidin production ENSG00000010704 ENSG00000106327 ENSG00000128791 ENSG00000105697 ENSG00000168610 ENSG00000130513 PMC3585130__F1 The Amidation Step of Diphthamide Biosynthesis in Yeast Requires DPH6, a Gene Identified through Mining the DPH1-DPH5 Interaction Network ENSG00000154813 ENSG00000167658 ENSG00000108963 PMC3585130__F2 Amidation Step of Diphthamide Biosynthesis in Yeast Requires DPH6, a Gene Identified through Mining the DPH1-DPH5 Interaction Network ENSG00000148399 ENSG00000134146 ENSG00000002549 ENSG00000108963 PMC4860420__F2 Reelin signaling mechanisms in brain development and function ENSG00000291971 ENSG00000010810 ENSG00000198793 ENSG00000173406 PMC4330253__F3 Illustration of molecular pathway for significantly associated single nucleotide polymorphism (SNP) loci in the metabolic syndrome genome-wide association study (GWAS) ENSG00000138778 ENSG00000122952 ENSG00000178999 ENSG00000170430 ENSG00000115009 ENSG00000086827 ENSG00000100065 ENSG00000149503 PMC9923939__F1 Traditional Chinese medicine for colorectal cancer treatment: potential targets and mechanisms of action ENSG00000177455 ENSG00000146648 PMC2277216__F1 Plasmacytoid dendritic cells and type I IFN: 50 years of convergent history ENSG00000239732 ENSG00000140968 ENSG00000172936 ENSG00000276561 PMC9923939__F2 Traditional Chinese medicine for colorectal cancer treatment: potential targets and mechanisms of action ENSG00000170458 ENSG00000102871 ENSG00000172936 ENSG00000175104 ENSG00000127191 PMC6929103__F3 KEGG based pathway analysis of 86 genes reveals their significant role in different pathways, as shown in the figure, such as immune response pathways ENSG00000135218 ENSG00000081237 ENSG00000081189 ENSG00000261371 ENSG00000108179 ENSG00000118785 ENSG00000128052 ENSG00000058668 ENSG00000277263 ENSG00000136160 ENSG00000174059 ENSG00000151617 ENSG00000026103 PMC9923939__F3 Traditional Chinese medicine for colorectal cancer treatment: potential targets and mechanisms of action ENSG00000102871 ENSG00000127191 ENSG00000026103 PMC9923939__F4 Traditional Chinese medicine for colorectal cancer treatment: potential targets and mechanisms of action ENSG00000137673 ENSG00000095739 ENSG00000134982 ENSG00000168036 PMC9923939__F5 Traditional Chinese medicine for colorectal cancer treatment: potential targets and mechanisms of action ENSG00000002330 ENSG00000163235 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC9923939__F6 Traditional Chinese medicine for colorectal cancer treatment: potential targets and mechanisms of action ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000026103 PMC4878077__F4 Shows the schematic presentation of the IFNA/B and IFNG receptors linked to the Jaks for the TO-VS-IFN/SAV3 and TO-VS-SAV3 ENSG00000159128 ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000027697 ENSG00000142166 PMC8377872__F5 Extracellular vesicle-associated miRNAs are an adaptive response to gestational diabetes mellitus ENSG00000147162 ENSG00000116266 ENSG00000107560 PMC9923939__F7 Traditional Chinese medicine for colorectal cancer treatment: potential targets and mechanisms of action ENSG00000170365 ENSG00000137834 ENSG00000156574 PMC9923939__F8 Traditional Chinese medicine for colorectal cancer treatment: potential targets and mechanisms of action ENSG00000145979 ENSG00000155792 PMC9923939__F9 Traditional Chinese medicine for colorectal cancer treatment: potential targets and mechanisms of action ENSG00000106571 ENSG00000136997 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC4878077__F5 Shows Jak/stat pathway analysis for the TO-VS-IFN/SAV3 and TO-VS-SAV3 using the KEGG pathway software analysis ENSG00000110395 ENSG00000137193 ENSG00000164399 PMC7386875__F1 Proposed mechanisms of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission, and coronavirus disease 2019 (COVID-19)-associated thrombosis ENSG00000140564 ENSG00000130234 ENSG00000184012 PMC4528959__F6 Quantitative phosphoproteomic analysis of IL-33 mediated signaling ENSG00000180210 ENSG00000070831 ENSG00000134982 ENSG00000138443 ENSG00000163914 ENSG00000102302 ENSG00000089159 PMC7386875__F4 Treatments for targeting coronavirus disease 2019 (COVID-19)-associated thrombosis ENSG00000130234 ENSG00000184012 ENSG00000189403 PMC3161051__F7 Rad6B/Beta-catenin regulation in breast cancer cells with autocrine Wnt activity ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4578258__F1 The schematic model for the regulation of the transcription of the srf operon network involved in two extracellular signaling peptide-mediated quorum sensing in B ENSG00000105664 PMC6424728__F1 Promoting immune evasion by Hippo pathway ENSG00000138798 ENSG00000146648 PMC3934928__F2 Cell biological view of Toll-like receptor function: regulation through compartmentalization ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 PMC3617288__F8 Model for the new PLD2-Fes-Jak3 pathway ENSG00000129219 ENSG00000182511 ENSG00000173599 ENSG00000105639 PMC8628936__F2 Organizer and Its Signaling in Embryonic Development ENSG00000162337 ENSG00000291971 ENSG00000134982 ENSG00000156574 ENSG00000168036 PMC3119055__F4 Gene Expression Profiling of Preovulatory Follicle in the Buffalo Cow: Effects of Increased IGF-I Concentration on Periovulatory Events ENSG00000197081 ENSG00000150907 ENSG00000143333 ENSG00000146648 ENSG00000104368 PMC6953127__F1 The Upstream Pathway of mTOR-Mediated Autophagy in Liver Diseases ENSG00000083290 ENSG00000144848 ENSG00000157954 ENSG00000145782 PMC3119055__F5 Gene Expression Profiling of Preovulatory Follicle in the Buffalo Cow: Effects of Increased IGF-I Concentration on Periovulatory Events ENSG00000197081 ENSG00000197635 ENSG00000150907 ENSG00000198793 ENSG00000122194 ENSG00000104368 PMC3296187__F1 Schematic representation of the RKIP signaling pathway and its effects on metastatic progression to the bone ENSG00000121966 ENSG00000156273 PMC9705593__F1 Crucial role of T cells in NAFLD-related disease: A review and prospect ENSG00000169245 ENSG00000186810 ENSG00000168610 ENSG00000115009 PMC6885781__F4 Toxic function evaluation in cancer EVs ENSG00000197915 ENSG00000182718 ENSG00000203786 ENSG00000143341 ENSG00000151655 ENSG00000171560 PMC3678031__F2 The amygdala and medial prefrontal cortex: partners in the fear circuit ENSG00000173599 ENSG00000105205 ENSG00000062485 PMC6287101__F7 Overview of complement cascade activation and targets of inhibitors ENSG00000009724 ENSG00000291559 ENSG00000125538 ENSG00000196352 ENSG00000117335 ENSG00000244731 ENSG00000166278 PMC2924916__F3 P-values for testing association of the genes within the MAPK signaling pathway with RA in NARAC studies ENSG00000087095 ENSG00000172680 ENSG00000157764 ENSG00000138798 ENSG00000177606 ENSG00000136997 ENSG00000130159 ENSG00000175104 ENSG00000127191 ENSG00000126458 ENSG00000136068 ENSG00000026103 PMC4377868__F1 Biological roles of sulphate and pathways of sulphate homeostasis ENSG00000129596 ENSG00000167941 ENSG00000139531 ENSG00000116761 PMC7328459__F1 Dysregulation of Cell Death in Human Chronic Inflammation ENSG00000137275 ENSG00000102871 ENSG00000082512 ENSG00000173039 ENSG00000166278 ENSG00000083799 ENSG00000168040 ENSG00000154124 ENSG00000127191 ENSG00000285379 PMC3398916__F7 The Rac activator Tiam1 is required for polarized protrusional outgrowth of primary astrocytes by affecting the organization of the microtubule network ENSG00000070831 ENSG00000156299 ENSG00000134982 PMC2924916__F2 P-values for testing association of the genes within the MAPK signaling pathway with RA in WTCCC studies ENSG00000087095 ENSG00000185652 ENSG00000172680 ENSG00000149930 ENSG00000170458 ENSG00000130522 ENSG00000138798 ENSG00000130159 ENSG00000101224 ENSG00000127191 PMC3008507__F5 A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets ENSG00000154027 ENSG00000283887 ENSG00000149573 ENSG00000281324 ENSG00000077235 ENSG00000169856 ENSG00000112559 ENSG00000165113 ENSG00000169562 ENSG00000177807 ENSG00000171202 ENSG00000039650 ENSG00000175591 ENSG00000124491 ENSG00000186141 ENSG00000148308 ENSG00000183196 ENSG00000143850 ENSG00000115207 ENSG00000205413 ENSG00000128268 ENSG00000124702 ENSG00000183765 ENSG00000126218 ENSG00000103479 ENSG00000005810 ENSG00000163171 ENSG00000175130 ENSG00000288411 ENSG00000213658 ENSG00000105808 ENSG00000292170 ENSG00000061337 ENSG00000291918 ENSG00000113722 ENSG00000147251 ENSG00000139687 ENSG00000251493 ENSG00000115091 ENSG00000108231 ENSG00000182742 ENSG00000095059 ENSG00000170027 ENSG00000187840 ENSG00000109814 ENSG00000157110 ENSG00000124216 ENSG00000206190 ENSG00000156127 ENSG00000112984 ENSG00000175104 ENSG00000075856 ENSG00000152661 ENSG00000181163 ENSG00000101000 ENSG00000182944 ENSG00000168036 ENSG00000166851 ENSG00000179295 ENSG00000049130 ENSG00000288185 ENSG00000128342 ENSG00000086730 ENSG00000100603 ENSG00000143515 ENSG00000110108 ENSG00000158458 ENSG00000100664 ENSG00000132664 ENSG00000139880 ENSG00000166401 ENSG00000135916 ENSG00000215021 ENSG00000162733 ENSG00000138674 ENSG00000106263 ENSG00000171848 ENSG00000277897 ENSG00000188763 ENSG00000155850 ENSG00000138385 PMC4695001__F7 Galeterone and VNPT55 induce proteasomal degradation of AR/AR-V7, induce significant apoptosis via cytochrome c release and suppress growth of castration resistant prostate cancer xenografts in vivo ENSG00000173409 ENSG00000069482 PMC8703004__F2 Alterations in Lysosome Homeostasis in Lipid-Related Disorders: Impact on Metabolic Tissues and Immune Cells ENSG00000135218 ENSG00000134982 ENSG00000186716 ENSG00000154059 PMC5076483__F4 Disturbed Flow-Induced Endothelial Proatherogenic Signaling Via Regulating Post-Translational Modifications and Epigenetic Events ENSG00000088305 ENSG00000139372 PMC11889934__F3 Molecular modifications of lactylation in cancer ENSG00000177169 ENSG00000170775 ENSG00000110514 ENSG00000198492 ENSG00000179094 ENSG00000112715 ENSG00000162692 ENSG00000172977 ENSG00000168610 ENSG00000075213 PMC11889934__F4 Anticancer strategies targeting lactylation ENSG00000121067 ENSG00000142082 ENSG00000131023 ENSG00000159399 PMC4805479__F2 Involvement of dWAT in Hair Follicle (HF) Synchronization.Synchronous cycling of HFs is connected with long-range paracrine signaling ENSG00000205221 ENSG00000164690 PMC11192909__F0 Mechanism of NGR1 in alleviating colitis ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8096981__F2 Inflammation-Mediated Angiogenesis in Ischemic Stroke ENSG00000002330 ENSG00000146648 PMC8741355__F4 Study of Yin-Chen-Hao-Tang Preventing and Treating Alcoholic Fatty Liver Disease through PPAR Signaling Pathway Based on Network Pharmacology and RNA-Seq Transcriptomics ENSG00000150991 ENSG00000167910 ENSG00000100979 ENSG00000113790 ENSG00000102977 PMC2756763__F1 Aromatase: synthesis of estrogen in postmenopausal women and its inhibition by aromatase inhibitors ENSG00000108786 PMC7378193__F7 Regulatory network of MYO18B mRNA that reflect the survival outcome in hepatocellular carcinoma ENSG00000275214 ENSG00000128641 ENSG00000111537 ENSG00000172216 ENSG00000133454 ENSG00000215375 PMC7183444__F3 Hypoxia/re-oxygenation-related KEGG pathway and differentially expressed genes(a) von Willebrand factor (VWF), complement component 1, q subcomponent, A chain (C1QA), and complement and coagulation cascades pathway ENSG00000277336 ENSG00000003436 ENSG00000113600 ENSG00000002330 ENSG00000110799 ENSG00000010278 ENSG00000117322 ENSG00000121966 ENSG00000180210 ENSG00000126218 ENSG00000117525 ENSG00000173372 ENSG00000163914 ENSG00000173599 ENSG00000198517 ENSG00000057593 ENSG00000282604 ENSG00000015285 ENSG00000080618 ENSG00000062485 PMC4512830__F6 Examples of IPA software outcome: hsa-let-7 and their target genes in Human Embryonic Stem Cell Pluripotency Pathway ENSG00000177606 ENSG00000185591 PMC2074956__F3 Schematic representation of the carbon catabolic pathway, the bifid shunt, and oxalic acid degradation ENSG00000038002 PMC3118436__F2 Metabolic remodeling in cancer cells and regulation by signaling pathways involving oncogenes and tumor suppressor genes ENSG00000136997 ENSG00000078237 ENSG00000115419 ENSG00000159399 ENSG00000026103 PMC3644824__F2 A schematic diagram of Mycobacterium tuberculosis (Mtb) infection and clearance via the autophagic pathway ENSG00000123576 ENSG00000111537 ENSG00000237693 ENSG00000166128 PMC6477881__F2 The mTOR-signaling pathway in ASD ENSG00000198793 ENSG00000196712 PMC6207557__F1 Mechanisms by which rLrp inhibits the production of LPS-induced cytokines ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC7306500__F2 Protein-protein interaction network (STRING database) generated by combining all biomarkers of different omic types, reviewed earlier in the report ENSG00000100234 ENSG00000170965 ENSG00000072274 ENSG00000162772 ENSG00000116183 ENSG00000105954 ENSG00000176978 ENSG00000106927 ENSG00000071282 ENSG00000123999 ENSG00000281165 ENSG00000005810 ENSG00000077150 ENSG00000119608 ENSG00000110013 ENSG00000113722 ENSG00000120915 ENSG00000105516 ENSG00000138495 ENSG00000070961 ENSG00000070404 ENSG00000023909 ENSG00000273936 ENSG00000148848 ENSG00000102172 ENSG00000161714 ENSG00000122254 ENSG00000102466 ENSG00000173692 PMC7322056__F6 Role of HX109 in prostate epithelial-macrophage crosstalk and inflammatory response of macrophages ENSG00000136869 ENSG00000168610 ENSG00000277943 PMC7749079__F1 Hippo signaling in embryogenesis and development ENSG00000126016 ENSG00000291971 ENSG00000144560 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC12238593__F5 Deregulated molecular signaling pathways and crosstalk in glioblastoma ENSG00000019991 ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000148400 ENSG00000138798 ENSG00000198793 ENSG00000155792 ENSG00000168036 ENSG00000125538 ENSG00000146648 ENSG00000196712 PMC12238593__F6 Key immune signaling pathways regulating tumor-associated immunosuppression ENSG00000291603 ENSG00000291971 ENSG00000198793 PMC12238593__F4 Genetic alterations driving glioblastoma pathogenesis ENSG00000149311 ENSG00000175054 ENSG00000157764 ENSG00000109321 ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000169184 ENSG00000146648 ENSG00000139687 ENSG00000117399 PMC12238593__F9 Transcriptional and epigenetic regulation and functional dynamics in CD8+ T cell exhaustion ENSG00000186810 ENSG00000117525 ENSG00000150907 ENSG00000020633 ENSG00000198846 ENSG00000283060 PMC4014333__F1 Biosynthetic pathway of prodigiosin ENSG00000069943 ENSG00000143315 ENSG00000108474 ENSG00000135845 ENSG00000100564 ENSG00000197563 ENSG00000206177 PMC4765774__F4 N-Terminal-Based Targeted, Inducible Protein Degradation in Escherichia coli ENSG00000166855 ENSG00000137392 ENSG00000125656 PMC5323377__F10 Schematic representation of the difference between Ctenopharyngodon idella melanoma differentiation-associated gene 5 (CiMDA5) and C ENSG00000276561 PMC3975838__F1 Janus kinase 2 (JAK2)/signal transducer and activation of transcription (STAT) and hedgehog (Hh) signaling pathways in normal development (A) and mechanisms of Hh signaling in cancer (B) ENSG00000106571 ENSG00000137193 ENSG00000171791 ENSG00000128602 PMC7724349__F8 Selaginellin B induces autophagy and apoptosis in ASPC-1 and PANC-1 cells through activating the JAK2/STAT3 signal pathway ENSG00000171791 ENSG00000168610 PMC3224393__F1 Reaction scheme for EGFR signal transduction pathway in H1299 cells ENSG00000110395 ENSG00000138798 ENSG00000146648 PMC9635867__F1 RNA m6A methylation regulators in endometrial cancer (Review) ENSG00000145388 ENSG00000198492 ENSG00000198793 ENSG00000169047 ENSG00000124766 ENSG00000146457 ENSG00000242265 ENSG00000126218 ENSG00000149658 ENSG00000040199 ENSG00000108821 ENSG00000165819 ENSG00000140443 PMC6291723__F4 Main lipid-lowering effects of berberine through the APMK pathway ENSG00000130164 ENSG00000042832 ENSG00000138668 PMC3385990__F3 Gp130 mediated IL-6 family of cytokines signaling pathway ENSG00000168610 PMC7418153__F1 An overview of Wnt signaling pathway ENSG00000281324 ENSG00000117153 ENSG00000162337 ENSG00000134982 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC7013402__F2 Greatwall- Endosulphin Alpha (ENSA) pathway in the control of G1 and G0 ENSG00000196511 ENSG00000176386 ENSG00000164327 ENSG00000138777 PMC7418153__F2 An overview of non-canonical Wnt signaling pathway ENSG00000070831 ENSG00000100592 ENSG00000112655 PMC2913986__F6 Gene Chip analysis reveal SOX11-induced regulation of Rb-E2F and TGFB signaling pathways PMC9604510__F2 Cell Component and Function of Tumor Microenvironment in Thyroid Cancer ENSG00000291971 PMC8835893__F5 Hedgehog Pathway Inhibitors as Targeted Cancer Therapy and Strategies to Overcome Drug Resistance ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 ENSG00000105204 PMC7758837__F1 Emerging therapies in Parkinson disease — repurposed drugs and new approaches ENSG00000089692 ENSG00000158828 PMC8835893__F2 Hedgehog Pathway Inhibitors as Targeted Cancer Therapy and Strategies to Overcome Drug Resistance ENSG00000291971 ENSG00000198793 ENSG00000133961 ENSG00000128602 PMC9246413__F2 Temozolomide – Just a Radiosensitizer? ENSG00000149311 ENSG00000175054 ENSG00000170430 PMC5911630__F7 The role of ACSS3 as a prognosis biosignature of GCa ENSG00000110921 ENSG00000111058 ENSG00000130164 ENSG00000109929 ENSG00000115271 ENSG00000062485 PMC8835893__F1 Hedgehog Pathway Inhibitors as Targeted Cancer Therapy and Strategies to Overcome Drug Resistance ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC5366285__F9 Cartoon illustrating a novel signaling pathway for the coordinated regulation of Rho and Rac signaling in epithelial invasion ENSG00000163914 ENSG00000147459 PMC8352204__F3A Machine Learning Identifies Clinical and Genetic Factors Associated With Anthracycline Cardiotoxicity in Pediatric Cancer Survivors ENSG00000051523 ENSG00000291745 ENSG00000008952 ENSG00000156026 ENSG00000178690 ENSG00000285348 ENSG00000064933 ENSG00000125780 ENSG00000151612 ENSG00000164411 ENSG00000197951 ENSG00000101489 ENSG00000137831 ENSG00000189067 PMC4027041__F1 Hepatic S-adenosylmethionine (SAMe) metabolism PMC4546523__F2 Biosynthesis of heparin/heparan sulfate and chondroitin sulfates ENSG00000069482 ENSG00000062485 ENSG00000111962 PMC5228377__F6 The signaling pathways involved in wogonin-induced autophagy ENSG00000177169 ENSG00000198793 ENSG00000083799 PMC9477170__F3 Inflammation resolution concept ENSG00000162711 PMC11419411__F2 Molecular mechanisms and pathways associated with PCa bone metastasis cells (By Figdraw) ENSG00000121068 ENSG00000168036 ENSG00000142089 ENSG00000177283 ENSG00000168610 PMC2727884__F2 Mechanism of action of sorafenib ENSG00000134086 ENSG00000163235 ENSG00000146648 PMC11787113__F2 Phenotypic and functional characteristics of tumor-infiltrating B cells determine their overall impact on tumor progression or suppression ENSG00000049768 PMC9635867__F2 RNA m6A methylation regulators in endometrial cancer (Review) ENSG00000145388 ENSG00000198492 ENSG00000040199 ENSG00000165819 PMC3864081__F1 DAMP signaling through different PRRs ENSG00000167207 ENSG00000172936 ENSG00000150455 ENSG00000106100 ENSG00000276561 PMC11640923__F4 Iron handling in the brain ENSG00000089472 ENSG00000105697 PMC8388390__F4 Effect of GP19 Peptide Hyperimmune Antiserum on Activated Macrophage during Ehrlichia canis Infection in Canine Macrophage-like Cells ENSG00000110944 ENSG00000159128 ENSG00000110324 ENSG00000154124 ENSG00000205220 ENSG00000168811 ENSG00000142224 ENSG00000111537 ENSG00000175899 ENSG00000113520 ENSG00000233816 ENSG00000184371 ENSG00000113302 ENSG00000162892 PMC11640923__F5 Pathomechanisms of FTD that might involve iron imbalance ENSG00000188021 ENSG00000182944 ENSG00000181867 ENSG00000276833 PMC3281649__F9 Proposed model for the inhibition of Notch1 signaling pathway by Fe65 ENSG00000148400 ENSG00000078747 ENSG00000273529 ENSG00000114315 PMC11640923__F2 Intestinal iron absorption (left) and iron handling in a generic cell (right) ENSG00000089472 ENSG00000116688 ENSG00000072274 ENSG00000105697 ENSG00000181867 PMC7789003__F1 Synthetic view of key functional losses (−) and gains (+) during the evolution of Myzozoa ENSG00000182511 PMC9648404__F8 Sexual dimorphism of early transcriptional reprogramming in degenerating peripheral nerves ENSG00000152266 ENSG00000019991 ENSG00000147162 ENSG00000105329 ENSG00000100906 ENSG00000138798 ENSG00000140505 ENSG00000108342 ENSG00000164399 ENSG00000140465 ENSG00000180210 ENSG00000111537 ENSG00000138166 ENSG00000124882 ENSG00000057593 ENSG00000125538 ENSG00000128342 ENSG00000146648 ENSG00000127948 PMC11640923__F3 Iron homeostasis by cellular iron levels (left) and oxidative stress (right) ENSG00000142192 ENSG00000072274 ENSG00000284099 ENSG00000167996 ENSG00000079999 PMC8582450__F10 Analysis of NIS Plasma Membrane Interactors Discloses Key Regulation by a SRC/RAC1/PAK1/PIP5K/EZRIN Pathway with Potential Implications for Radioiodine Re-Sensitization Therapy in Thyroid Cancer ENSG00000122218 ENSG00000291971 ENSG00000149269 PMC7828590__F1 ERA activity through genomic and nongenomic actions ENSG00000291971 ENSG00000185591 PMC4021685__F1 Schematic simplified demonstration of the main mechanisms supposed to be involved in fatty acid and TNF family interaction at different levels of colon epithelial cell organisation ENSG00000111537 ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC6132443__F2 Role of NaPiII family of sodium–phosphate cotransporters in the intestines and in the kidney ENSG00000118972 ENSG00000152266 ENSG00000077782 PMC9260022__F4 ILP-2: A New Bane and Therapeutic Target for Human Cancers ENSG00000198793 PMC6126464__F2 The IL-6 receptor signaling pathway that is regulated by TRAF2 and TRAF5 ENSG00000082512 ENSG00000127191 ENSG00000168610 PMC7919195__F6 Signaling pathway network of potential AA targets ENSG00000168748 ENSG00000157404 ENSG00000150594 ENSG00000158748 ENSG00000112715 ENSG00000135914 ENSG00000274286 ENSG00000102468 ENSG00000149295 ENSG00000143801 ENSG00000185015 ENSG00000205155 ENSG00000167434 PMC8172602__F9 Prolyl Endopeptidase Gene Disruption Improves Gut Dysbiosis and Non-alcoholic Fatty Liver Disease in Mice Induced by a High-Fat Diet ENSG00000169710 ENSG00000184207 ENSG00000096717 PMC11033433__F2 Research progress on radiation resistance of cervical cancer ENSG00000147649 ENSG00000185379 ENSG00000117650 ENSG00000135100 ENSG00000029993 ENSG00000171791 ENSG00000089163 ENSG00000125084 PMC3444627__F1 Cytokine Combination Therapy Prediction for Bone Remodeling in Tissue Engineering Based on the Intracellular Signaling Pathway ENSG00000178860 ENSG00000152266 ENSG00000170365 ENSG00000168036 PMC4413642__F6 Slit2/Robo1 signaling promotes intestinal tumorigenesis through Src-mediated activation of the Wnt/Beta-catenin pathway ENSG00000145147 ENSG00000291971 ENSG00000168036 PMC6286919__F1 Schematic representation illustrating the signaling molecules that regulate the PD-1/PD-L1 transcription ENSG00000134982 ENSG00000168610 PMC3886813__F1 NFKB and STAT3 signaling in glioma: targets for future therapies ENSG00000104856 PMC11033433__F6 Research progress on radiation resistance of cervical cancer ENSG00000087245 ENSG00000137673 PMC3886813__F2 NFKB and STAT3 signaling in glioma: targets for future therapies ENSG00000099985 ENSG00000168610 PMC11033433__F7 Non-coding RNAs involved in the regulation of radiation tolerance in cervical cancer (A) the relationship between lncRNAs and radiotherapy resistance in cervical cancer ENSG00000100811 ENSG00000163739 ENSG00000198492 ENSG00000198793 ENSG00000099942 ENSG00000124762 ENSG00000260027 ENSG00000198252 ENSG00000066044 ENSG00000171848 ENSG00000051180 ENSG00000105810 ENSG00000165819 PMC11033433__F4 Research progress on radiation resistance of cervical cancer ENSG00000149311 ENSG00000134057 ENSG00000167754 ENSG00000018869 PMC516236__F1 Simplified representation of molecular mechanism involved in insulin signaling pathway that regulates glucose transporter (GLUT4) translocation to cell membrane ENSG00000124102 ENSG00000169047 PMC7563597__F2 Molecular mechanism of extrinsic and intrinsic pathway involved in apoptosis ENSG00000002330 ENSG00000102871 ENSG00000168040 ENSG00000104081 PMC4938032__F3 Signals shared after brain injury and in the NSC niche ENSG00000163235 ENSG00000138798 ENSG00000198793 ENSG00000131095 ENSG00000205927 ENSG00000164690 ENSG00000146648 PMC10153444__F2 Contribution of the dihydropyrimidinase-like proteins family in synaptic physiology and in neurodevelopmental disorders ENSG00000010810 ENSG00000075213 PMC3210456__F7 Cyclin D1 action and degradation ENSG00000036672 PMC8232086__F1 Emerging Role and Clinicopathological Significance of AEG-1 in Different Cancer Types: A Concise Review ENSG00000147649 ENSG00000136997 ENSG00000168036 PMC8232086__F2 Emerging Role and Clinicopathological Significance of AEG-1 in Different Cancer Types: A Concise Review ENSG00000102034 ENSG00000182197 ENSG00000198793 ENSG00000128602 PMC11930081__F8 Proposed signaling pathway activated by oxidative stress in NHEKs ENSG00000136026 ENSG00000265972 ENSG00000146648 PMC7788945__F1 IL-22R downstream signal transduction pathways ENSG00000105397 ENSG00000115415 ENSG00000168610 PMC7200337__F6 Immunology of COVID-19: Current State of the Science ENSG00000108691 ENSG00000239732 ENSG00000130234 PMC10538627__F2 Research progress on the role of the Wnt signaling pathway in pituitary adenoma ENSG00000162552 ENSG00000156076 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000168646 PMC8723792__F3 Translational science of cancers with SWI/SNF complex aberrations ENSG00000175054 ENSG00000135446 ENSG00000049618 ENSG00000105810 ENSG00000077782 ENSG00000127616 PMC3856862__F10 Therapeutic Strategies to Increase Human Beta-Cell Growth and Proliferation by Regulating mTOR and GSK-3/Beta-Catenin Pathways ENSG00000169047 ENSG00000198793 ENSG00000168036 PMC8584977__F5 Wnt Signaling in Inner Blood–Retinal Barrier Maintenance ENSG00000281324 ENSG00000162337 ENSG00000174804 ENSG00000168036 PMC4473799__F3 Targeting signaling factors for degradation, an emerging mechanism for TRAF functions ENSG00000104856 ENSG00000183735 ENSG00000088888 ENSG00000172005 ENSG00000173039 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC8932066__F4 Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments ENSG00000085117 ENSG00000110651 ENSG00000010278 ENSG00000135404 PMC10538627__F1 Research progress on the role of the Wnt signaling pathway in pituitary adenoma ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000179091 ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000168646 PMC9331252__F6 Mulberry Leaf and Neochlorogenic Acid Alleviates Glucolipotoxicity-Induced Oxidative Stress and Inhibits Proliferation/Migration via Downregulating Ras and FAK Signaling Pathway in Vascular Smooth Muscle Cell ENSG00000132646 PMC8299464__F2 Stress Hormones: Emerging Targets in Gynecological Cancers PMC4320218__F1 PI3K/Akt/mTOR signaling pathway ENSG00000177169 PMC7576747__F3 Intervention to reduce ROS for the prevention of CIN: evidence from in vitro, in vivo and clinical studies ENSG00000181019 ENSG00000198793 ENSG00000163914 ENSG00000096717 PMC7576747__F2 CIN via complex pathways of ROS from in vitro and in vivo studies ENSG00000115415 ENSG00000163914 ENSG00000185591 ENSG00000096717 PMC10571651__F1 Normal physiologic MET receptors form dimers upon HGF signaling, and Cbl binding leads to ubiquitination ENSG00000019991 ENSG00000110395 ENSG00000291971 PMC8310235__F3 Human Papillomaviruses Target the DNA Damage Repair and Innate Immune Response Pathways to Allow for Persistent Infection ENSG00000183735 ENSG00000213928 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000144895 ENSG00000115415 ENSG00000163565 PMC2992472__F4 The regulatory network of apoptosis in BCL11B and its related genes ENSG00000005339 ENSG00000118785 ENSG00000168040 PMC8344275__F1 Deregulation of HLA-I in cancer and its central importance for immunotherapy ENSG00000159128 ENSG00000027697 ENSG00000273686 ENSG00000125347 ENSG00000146648 ENSG00000142166 PMC8071039__F2 Signaling pathway and cell survival ENSG00000002330 ENSG00000154059 ENSG00000171791 ENSG00000184916 PMC10309513__F2 Triggering receptor expressed on myeloid cells 2–apolipoprotein E signaling pathway in diseases ENSG00000167601 ENSG00000103449 ENSG00000140678 ENSG00000204103 ENSG00000172243 ENSG00000118785 ENSG00000077984 ENSG00000129226 ENSG00000184371 ENSG00000010278 ENSG00000136235 PMC8071039__F4 Signaling pathway and cell migration ENSG00000163914 ENSG00000154059 ENSG00000168036 PMC4647707__F3 Differentially expressed genes in the toll-like receptor signalling pathway (ko04620) ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000142224 ENSG00000164342 ENSG00000143387 PMC6912555__F1 Canonical and noncanonical Wnt signaling pathways ENSG00000138795 ENSG00000134982 ENSG00000163914 ENSG00000102312 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000173273 PMC2734294__F3 Several molecular features in the cell body of an oxidatively stressed neuron ENSG00000181019 ENSG00000079999 PMC4647707__F4 Differentially expressed genes in the cytokine-cytokine receptor interaction pathway (ko04060) ENSG00000134460 ENSG00000157404 ENSG00000183625 ENSG00000139269 ENSG00000163083 ENSG00000164399 ENSG00000274736 ENSG00000111321 ENSG00000187266 ENSG00000122025 ENSG00000131142 ENSG00000135960 ENSG00000122756 ENSG00000117400 ENSG00000292373 ENSG00000128052 ENSG00000147896 ENSG00000113520 ENSG00000037280 ENSG00000162892 ENSG00000112486 ENSG00000026103 ENSG00000112964 ENSG00000099985 ENSG00000145777 ENSG00000277943 ENSG00000162594 ENSG00000226275 ENSG00000108691 ENSG00000145839 ENSG00000168066 ENSG00000137077 ENSG00000126353 ENSG00000204217 ENSG00000113494 ENSG00000016402 PMC3340256__F1 tBID structure and mechanism of action ENSG00000285121 PMC5707070__F8 Alpha-Tocopherol prevents esophageal squamous cell carcinoma by modulating PPARGamma-Akt signaling pathway at the early stage of carcinogenesis ENSG00000002330 PMC5381403__F1 Exome sequencing identifies frequent mutation of MLL2 in non–small cell lung carcinoma from Chinese patients ENSG00000125482 ENSG00000171105 ENSG00000007237 ENSG00000108799 ENSG00000117139 ENSG00000108819 ENSG00000149311 ENSG00000175054 ENSG00000120533 ENSG00000198730 ENSG00000041515 ENSG00000115593 ENSG00000115825 ENSG00000176165 ENSG00000133119 ENSG00000146648 ENSG00000127616 PMC6901958__F1 HSV-1 mediated evasion of the DNA-sensing pathway in innate immunity ENSG00000122566 ENSG00000183735 ENSG00000213928 ENSG00000164430 ENSG00000213658 ENSG00000138135 ENSG00000105397 ENSG00000163565 PMC9405826__F7 ALCAM: A Novel Surface Marker on EpCAMlow Circulating Tumor Cells ENSG00000087245 ENSG00000109320 ENSG00000138798 ENSG00000168036 ENSG00000171791 PMC7472745__F5 G2/M cell cycle arrest and mechanisms by which it is affected by Vpr ENSG00000145041 ENSG00000149311 ENSG00000175054 ENSG00000154920 ENSG00000166851 PMC4171549__F2 Computational gene interaction predictions: network of E12 telencephalon-specific miRNA involved in the Neurotransmitters and other nervous system signalling pathways ENSG00000111229 ENSG00000123700 ENSG00000104365 ENSG00000165119 ENSG00000170775 ENSG00000070831 ENSG00000185591 ENSG00000143933 ENSG00000146648 ENSG00000162104 ENSG00000137267 PMC11670864__F1 Generation of B10 cells via in vitro stimulation of TLR pathways ENSG00000095585 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000131323 PMC8503602__F3 Mitophagy in Diabetic Cardiomyopathy: Roles and Mechanisms ENSG00000281324 ENSG00000162337 ENSG00000112561 ENSG00000168036 PMC11670864__F2 BCR and CD19 signaling pathways work together to promote production of IL-10 ENSG00000177455 ENSG00000291971 ENSG00000198793 PMC7472745__F1 Replication cycle of HIV: graphical depiction of the major events of the HIV replication cycle ENSG00000121966 PMC10778571__F3 Pathways regulated by DKK-3: insights into DKK-3 functions ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000050165 ENSG00000136026 PMC3843585__F2 The PI3K signaling pathway ENSG00000002330 ENSG00000291971 PMC2757120__F1 Canonical PI3K signaling pathway ENSG00000169047 ENSG00000177606 ENSG00000136997 PMC3189826__F1 p130Cas and p140Cap signalling involved in migration and invasion ENSG00000291971 PMC2882232__F2 Simplified representation of oncogenic signaling cascades in pancreatic cancer ENSG00000019991 ENSG00000281324 ENSG00000291971 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000100744 ENSG00000146648 ENSG00000140443 PMC9454979__F6 Novel Insights into miR-944 in Cancer ENSG00000141448 ENSG00000115415 ENSG00000291971 ENSG00000138798 ENSG00000114737 ENSG00000145321 ENSG00000168036 ENSG00000183742 ENSG00000180008 ENSG00000168610 ENSG00000146648 PMC6036858__F1 Yeast cell cycle pathway from the KEGG database ENSG00000261832 ENSG00000142178 ENSG00000171444 ENSG00000134982 ENSG00000157884 ENSG00000172005 ENSG00000115942 ENSG00000135336 ENSG00000166278 ENSG00000140743 ENSG00000117399 PMC6657977__F7 Circular RNA profile in liver tissue of EpCAM knockout mice ENSG00000159128 ENSG00000135100 ENSG00000185745 ENSG00000164327 ENSG00000276068 ENSG00000118503 ENSG00000177606 ENSG00000292130 ENSG00000051825 ENSG00000165323 ENSG00000168763 ENSG00000050130 ENSG00000183475 ENSG00000163082 PMC3189826__F7 Signaling pathways leading to 3D invasion of ErbB2 transformed MCF10 cells over-expressing p130Cas ENSG00000198793 PMC11719987__F6 Role of Notch signaling in modulating ferroptosis and its contribution to cataract formation ENSG00000151012 ENSG00000167468 ENSG00000167996 PMC7066404__F9 Potential mechanisms of hKLK1's protective effects on DMED ENSG00000105329 PMC6036858__F2 Gene network of the yeast data related to the cell cycle pathway via the JMCCM ENSG00000261832 ENSG00000115266 ENSG00000135336 ENSG00000112118 ENSG00000076003 ENSG00000117399 ENSG00000166508 PMC3823407__F8 Proposed model of the effect of crocetin on cardiac hypertrophy, inflammation and fibrosis ENSG00000285109 PMC8566568__F5 RNASeq analysis of drought-stressed guayule reveals the role of gene transcription for modulating rubber, resin, and carbohydrate synthesis ENSG00000197429 ENSG00000120437 ENSG00000075239 PMC8826583__F2 Long Noncoding RNA GAS5: A New Factor Involved in Bone Diseases ENSG00000176692 ENSG00000168036 ENSG00000108840 PMC5502539__F4 Complement factors are targets for pharmacologic inhibition in retinal disease ENSG00000274619 PMC5705340__F2 KEGG Ras signaling pathway with targetable nodes highlighted in red ENSG00000146909 ENSG00000002330 ENSG00000213658 PMC4203564__F1 KIAA1524/CIP2A promotes cancer growth by coordinating the activities of MTORC1 and MYC ENSG00000136997 ENSG00000108443 ENSG00000187840 ENSG00000163507 PMC9315392__F3 B-Cell in the Pathogenesis of Systemic Sclerosis ENSG00000177455 ENSG00000186716 ENSG00000125538 PMC6063820__F2 Maintenance of a quiescent primordial follicle is regulated by Hippo and Akt signaling ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC7807182__F6 LPS affecting glucose metabolism in cervical cancer cells through FRA1: LPS inhibits p53 by inhibiting the expression of FRA1, which regulates the levels of glycolysis and aerobic oxidation by affecting downstream GLUT1, G6PD and SCO2 ENSG00000284194 PMC6063820__F3 Activation of a primordial follicle is regulated by Hippo and Akt signaling ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC10136584__F1 WNT signaling pathways ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000100592 ENSG00000134982 PMC1190355__F8 A model of IRAK1c regulation of inflammation ENSG00000172936 ENSG00000175104 PMC6591252__F8 The proposed model for the scaffolding role of the IQ3 motif in IQGAP1 towards the PI3K-Akt pathway ENSG00000140575 ENSG00000138798 ENSG00000146648 PMC3174148__F4 Predictive Power Estimation Algorithm (PPEA) - A New Algorithm to Reduce Overfitting for Genomic Biomarker Discovery ENSG00000103811 ENSG00000187688 ENSG00000173786 ENSG00000277263 ENSG00000133111 PMC3972890__F6 CXCR4 negatively regulates keratinocyte proliferation in IL-23-mediated psoriasiform dermatitis ENSG00000107562 ENSG00000168610 ENSG00000121966 PMC10411462__F8 Function and mechanism of PARP inhibitor in thyroid cancers ENSG00000143799 ENSG00000118518 PMC8700581__F3 Senescence Alterations in Pulmonary Hypertension ENSG00000086991 ENSG00000204217 PMC8194268__F1 Mesenchymal Stem Cell Protects Injured Renal Tubular Epithelial Cells by Regulating mTOR-Mediated Th17/Treg Axis ENSG00000178860 ENSG00000198793 ENSG00000168610 PMC9194868__F2 Fueling genome maintenance: On the versatile roles of NAD+ in preserving DNA integrity ENSG00000291814 ENSG00000123572 ENSG00000278488 ENSG00000157064 ENSG00000173614 PMC8700067__F4 Autophagy-Lysosomal Pathway as Potential Therapeutic Target in Parkinson’s Disease ENSG00000177169 ENSG00000198793 ENSG00000112561 ENSG00000145782 PMC8700067__F2 Autophagy-Lysosomal Pathway as Potential Therapeutic Target in Parkinson’s Disease ENSG00000177169 ENSG00000198793 ENSG00000145782 PMC8700067__F3 Autophagy-Lysosomal Pathway as Potential Therapeutic Target in Parkinson’s Disease ENSG00000123240 ENSG00000284099 ENSG00000158828 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC9170180__F1 Three Proliferation Pathways (Wnt, Notch, and Hippo) in Intestine and Immune System and Their Role in Inflammatory Bowel Diseases (IBDs) ENSG00000134982 ENSG00000137845 ENSG00000131023 PMC8922216__F2 Metabolic and Signaling Roles of Ketone Bodies in Health and Disease ENSG00000131473 ENSG00000079432 PMC6129971__F1 Pathways of one-carbon metabolism ENSG00000205221 PMC7920303__F3 Metabolism of small, neutral amino acids including serine (Ser), glycine (Gly), and alanine (Ala) ENSG00000143158 ENSG00000144659 ENSG00000115902 ENSG00000205221 ENSG00000092621 ENSG00000164466 ENSG00000135069 ENSG00000111371 ENSG00000146733 ENSG00000166123 ENSG00000060762 PMC11993586__F1 Lipid synthesis pathways and associated proteins in this review ENSG00000067064 ENSG00000163624 ENSG00000228278 ENSG00000146005 ENSG00000173599 ENSG00000166123 ENSG00000229314 PMC5131952__F7 Silver Nanoparticle-Directed Mast Cell Degranulation Is Mediated through Calcium and PI3K Signaling Independent of the High Affinity IgE Receptor ENSG00000167323 ENSG00000293604 PMC8836921__F1 IL-6 Cytokine Family: A Putative Target for Breast Cancer Prevention and Treatment ENSG00000145623 ENSG00000099985 ENSG00000128342 PMC7478175__F7 The complosome in T cell homeostasis ENSG00000148400 ENSG00000117335 ENSG00000168685 PMC4767381__F2 The canonical pathway of miRNA biogenesis and the mechanisms of miRNA controlled posttranscriptional gene regulation ENSG00000113360 ENSG00000123908 PMC7422669__F3 Engulfment of apoptotic tumor cells induces LAP to inhibit type I IFN response and polarize tumor associated macrophages toward the immunosuppressive M2 phenotype ENSG00000111537 ENSG00000125538 PMC7422669__F1 Clearance processes for apoptotic cell by phagocytes rely on “find me” and “eat me” signals that signal their internalization (A) “Find me” signal: apoptotic cells release signals that attract phagocytes to the site of programmed cell death ENSG00000186810 ENSG00000153208 ENSG00000105329 PMC6563926__F1 Physiological pathways of LRRK2 activity ENSG00000136869 ENSG00000084733 PMC6033032__F2 Schematic/pathway representation of the FOXO‐p53 interplay in cellular senescence ENSG00000149311 ENSG00000117525 ENSG00000150907 ENSG00000184481 PMC6838865__F1 Canonical and non-canonical mammalian autophagy processes ENSG00000123395 ENSG00000198382 ENSG00000126775 ENSG00000198793 ENSG00000145782 PMC5026797__F1 mTORC1 re-wires GI cell metabolism upon glycolysis inhibition to promote growth and proliferation ENSG00000084774 PMC8483912__F3 Stingless Bee Propolis: New Insights for Anticancer Drugs ENSG00000019991 ENSG00000002330 ENSG00000138798 ENSG00000198793 ENSG00000123374 ENSG00000124762 PMC11701242__F6 Molecular mechanisms of phase separation in TGFB, NFKB, and JAK-STAT pathway ENSG00000168036 ENSG00000168610 PMC11701242__F7 Phase separation-mediated MAPK/ERK activation of T cell signaling pathways ENSG00000291603 ENSG00000213658 ENSG00000134982 ENSG00000124181 PMC9710158__F1 Cancer ego-system in glioma: an iron-replenishing niche network systemically self-organized by cancer stem cells ENSG00000177575 ENSG00000108691 ENSG00000049130 ENSG00000198053 ENSG00000129226 ENSG00000184371 ENSG00000164400 ENSG00000121807 PMC11701242__F4 Pathogenesis and therapeutic resistance mediated by the phase separation of the Hippo pathway ENSG00000013619 ENSG00000141867 ENSG00000183735 ENSG00000186575 ENSG00000088888 ENSG00000125686 ENSG00000150457 ENSG00000131023 PMC11701242__F5 Molecular mechanisms of phase separation in cGAS-STING-mediated innate immune responses ENSG00000183735 ENSG00000164430 ENSG00000096717 ENSG00000276561 PMC11701242__F3 Mechanism and activation of the Hippo pathway through phase separation ENSG00000126016 ENSG00000163681 ENSG00000150457 ENSG00000131023 PMC3073741__F1 Complement and Viral Pathogenesis ENSG00000039537 ENSG00000113600 ENSG00000203710 ENSG00000244731 ENSG00000117322 PMC5356782__F2 Therapeutic potential of targeting the PI3K pathway in pediatric brain tumors ENSG00000002330 ENSG00000198793 PMC6632497__F5 Modulating PI3K-Akt signaling pathway of SCD ENSG00000103479 ENSG00000101146 ENSG00000002330 ENSG00000186716 ENSG00000198793 PMC11012486__F1 Identification of PTPN12 Phosphatase as a Novel Negative Regulator of Hippo Pathway Effectors YAP/TAZ in Breast Cancer ENSG00000167601 ENSG00000070778 ENSG00000126016 ENSG00000078747 ENSG00000163914 ENSG00000198670 ENSG00000150457 ENSG00000131023 ENSG00000123124 PMC5356782__F1 Therapeutic potential of targeting the PI3K pathway in pediatric brain tumors ENSG00000002330 ENSG00000198793 PMC4449903__F1 Visualized thrombosis network ENSG00000112977 ENSG00000113905 ENSG00000134215 ENSG00000141639 ENSG00000160293 ENSG00000141968 PMC9380231__F6 Effect of Rhizoma Drynariae on differential gene expression in ovariectomized rats with osteoporosis based on transcriptome sequencing ENSG00000149968 PMC8766410__F3 Adenosinergic Signaling as a Key Modulator of the Glioma Microenvironment and Reactive Astrocytes ENSG00000196839 ENSG00000170425 PMC3980079__F1 Heart Failure and Loss of Metabolic Control ENSG00000157184 ENSG00000135218 ENSG00000042832 ENSG00000173599 PMC11701242__F9 Phase separation in Notch signaling for oncogenic Myc activation and developmental fate control ENSG00000141867 ENSG00000205476 ENSG00000168214 ENSG00000125686 ENSG00000133961 PMC6278416__F11 ERK/MAPK signaling pathway in liver metastasis of colorectal cancer ENSG00000183943 ENSG00000136068 PMC6283264__F7 The TLR pathway and let-7e target mRNAs ENSG00000174125 ENSG00000168040 ENSG00000150455 ENSG00000276561 ENSG00000007171 ENSG00000183735 ENSG00000239732 ENSG00000170458 ENSG00000125538 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000064012 ENSG00000184216 PMC8947257__F8 Proposed model of RTK bypass pathway activation in Tpl2 -/- keratinocytes ENSG00000171105 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC8533192__F7 Irradiation Mediates IFNA and CXCL9 Expression in Non-Small Cell Lung Cancer to Stimulate CD8+ T Cells Activity and Migration toward Tumors ENSG00000169245 ENSG00000186810 ENSG00000164430 ENSG00000111537 ENSG00000138755 ENSG00000180644 PMC4449815__F8 Inactivation of a GAs-PKA tumor suppressor pathway in skin stem cells initiates basal-cell carcinogenesis ENSG00000186575 ENSG00000164690 ENSG00000128602 PMC6520835__F1 Canonical SMO-dependent HH/GLI signaling ENSG00000143147 ENSG00000106571 ENSG00000144857 ENSG00000128602 PMC6520835__F2 Genetic and molecular mechanisms conferring resistance to SMO inhibitors ENSG00000143147 ENSG00000144857 ENSG00000198793 ENSG00000128602 PMC5218554__F9 Wnt Signaling Prevents the AB Oligomer-Induced Mitochondrial Permeability Transition Pore Opening Preserving Mitochondrial Structure in Hippocampal Neurons ENSG00000154342 ENSG00000281324 ENSG00000134982 PMC7244035__F7 Schematic figure represented the functions of KIF23 in the Wnt/Beta-catenin signaling pathway in GC ENSG00000137807 ENSG00000198901 ENSG00000184675 ENSG00000134982 ENSG00000168036 PMC9355403__F8 Of ATP5MG to Treat Metabolic Syndrome-Associated Cardiovascular Diseases ENSG00000167283 ENSG00000178741 ENSG00000146701 ENSG00000166136 PMC6520835__F3 Therapeutic targeting of oncogenic HH/GLI signaling in cancer cells resistant to SMOi ENSG00000143147 ENSG00000141867 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000114315 ENSG00000128602 ENSG00000168610 ENSG00000105204 PMC6245347__F4 The miRNA-target genes involved in cancer signaling pathways ENSG00000142538 ENSG00000136997 ENSG00000026103 PMC6697716__F6 Putative signalling pathway of Ctyl1 ENSG00000125398 ENSG00000121807 ENSG00000170891 PMC5228544__F1 Roles of TBX2 and TBX3 in tumorigenesis and tumor progression ENSG00000117020 ENSG00000121068 ENSG00000170558 ENSG00000168036 ENSG00000135111 ENSG00000167653 ENSG00000140464 ENSG00000275051 PMC3505266__F3 Heterogeneity in the differentiation and function of memory B cells ENSG00000186716 PMC3959597__F7 Cross talk between metformin, androgens, and IGF system and molecular mechanisms of metformin inhibitory effects ENSG00000291971 ENSG00000198793 PMC9632889__F10 Potential mechanism of the effects of leonurine attenuating cardiac fibrosis in heart failure ENSG00000278718 ENSG00000291748 PMC7350219__F1 Cytosolic DNA sensing and pathway activation ENSG00000183735 ENSG00000164430 ENSG00000175104 PMC4080180__F12 Current understanding of LPA/LPA5R stimulation of NHE3 activity and mobility based on current studies and the previous reports from the laboratory of Yun and colleagues (, ) ENSG00000065054 ENSG00000163914 ENSG00000198670 ENSG00000146648 PMC4636730__F2 Proposed schematic of intracellular immune response to murine norovirus (MNV) infection ENSG00000187608 ENSG00000115415 ENSG00000276561 PMC3359223__F1 Glycolysis metabolic pathway ENSG00000091140 PMC2136409__F8A Genetic and epigenetic mechanisms of gene regulation during lens development ENSG00000138083 ENSG00000170558 ENSG00000123374 ENSG00000114315 PMC7282943__F1 Transforming growth factor-beta in immune suppression and chronic inflammation of squamous cell carcinomas ENSG00000163914 ENSG00000175104 ENSG00000076604 PMC7161743__F2 Leishmania heme auxotrophy ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000188690 PMC9120235__F4 OncoboxPD: human 51 672 molecular pathways database with tools for activity calculating and visualization ENSG00000110514 ENSG00000102871 ENSG00000291971 ENSG00000102245 ENSG00000065559 ENSG00000172936 ENSG00000168040 ENSG00000150455 PMC9120235__F5 OncoboxPD: human 51 672 molecular pathways database with tools for activity calculating and visualization ENSG00000173540 ENSG00000100417 PMC11343602__F8 Schematic diagram illustrating the mechanism and intervention strategies of the IL-27/Blimp-1 axis in regulating Tim-3 expression on Tregs ENSG00000115415 ENSG00000181847 ENSG00000168610 PMC6469996__F6 Pathways regulated by NNMT and proposed working model of mechanisms of action of NNMT inhibition as it relates to muSC activation and metabolic state in aged muscle tissue ENSG00000105835 ENSG00000123572 ENSG00000096717 ENSG00000138356 PMC3996895__F1 Biogenesis of canonical and mirtron miRNAs in animal cells ENSG00000128191 ENSG00000113360 ENSG00000132341 PMC6669816__F8 Mechanism by which eucalyptol protects APAP induced liver injury ENSG00000142192 ENSG00000130649 ENSG00000079999 PMC3996895__F2 Canonical NFKB signaling network regulated by miRNAs ENSG00000172936 ENSG00000083799 PMC5504484__F4 Signaling pathways assigned to the Ingenuity Pathway Analysis (IPA) category “molecular mechanisms of cancer” that have been linked to ovarian cancer and targeted by epigallocatechin‐3‐gallate (EGCG) ENSG00000138795 ENSG00000002330 ENSG00000157764 ENSG00000134982 ENSG00000169047 ENSG00000177606 ENSG00000136997 ENSG00000128602 ENSG00000080839 PMC3383335__F1 SnoN Signaling in Proliferating Cells and Postmitotic Neurons ENSG00000033800 PMC7600388__F1 Summary of hepatic lipid metabolism pathways altered in NAFLD and driving dyslipidemia ENSG00000130173 ENSG00000130164 ENSG00000042832 ENSG00000100344 ENSG00000105550 ENSG00000169710 ENSG00000132855 ENSG00000169174 PMC4400057__F3 NEMix: Single-cell Nested Effects Models for Probabilistic Pathway Stimulation ENSG00000157445 ENSG00000146648 PMC3797786__F3 Identification of Cisplatin-Regulated Metabolic Pathways in Pluripotent Stem Cells ENSG00000228716 ENSG00000088826 ENSG00000066926 ENSG00000103024 ENSG00000100033 ENSG00000070669 ENSG00000291507 ENSG00000166501 ENSG00000143179 ENSG00000120265 ENSG00000116120 ENSG00000197586 ENSG00000135929 ENSG00000067057 ENSG00000171302 ENSG00000162396 ENSG00000196839 ENSG00000111701 ENSG00000124370 ENSG00000103202 ENSG00000198931 ENSG00000145982 ENSG00000167900 ENSG00000102172 ENSG00000159921 ENSG00000187097 ENSG00000137364 ENSG00000156110 ENSG00000175198 ENSG00000171848 ENSG00000115361 PMC9465159__F1 Enhancing anti-tumour innate immunity by targeting the DNA damage response and pattern recognition receptors in combination with radiotherapy ENSG00000143799 ENSG00000276561 ENSG00000149311 ENSG00000175054 ENSG00000164430 ENSG00000088888 ENSG00000125538 ENSG00000113520 ENSG00000134070 ENSG00000172936 ENSG00000131323 ENSG00000184216 ENSG00000138385 PMC5955808__F1 Colorectal cancer prevention: immune modulation taking the stage ENSG00000157764 ENSG00000134982 ENSG00000163599 ENSG00000168036 PMC2924553__F1 BMP signal transduction ENSG00000087095 ENSG00000170365 ENSG00000157933 ENSG00000168036 PMC5674651__F2 Homocysteine metabolic pathway ENSG00000116984 PMC8129370__F3 Value of miRNAs in the prognosis of obese patients receiving bariatric surgery PMC7760708__F6 Top two signaling pathways regulated by miR-215-5p in CRC ENSG00000136457 ENSG00000135218 ENSG00000110799 ENSG00000010810 ENSG00000177606 ENSG00000026508 ENSG00000152592 PMC8951629__F2 Escape and Over-Activation of Innate Immune Responses by SARS-CoV-2: Two Faces of a Coin ENSG00000183735 ENSG00000088888 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000121060 ENSG00000276561 PMC4361049__F1 A stepwise demonstration of the hepatitis C virus internal ribosome entry site (HCV IRES) translation initiation pathway ENSG00000143486 ENSG00000163435 ENSG00000115008 ENSG00000144895 PMC8085490__F5 Genetic Manipulation of Sirtuin 3 Causes Alterations of Key Metabolic Regulators in Melanoma ENSG00000131473 ENSG00000223573 ENSG00000125166 ENSG00000179242 ENSG00000102471 ENSG00000103150 ENSG00000139697 ENSG00000163541 ENSG00000175567 ENSG00000278615 ENSG00000142082 ENSG00000131828 ENSG00000139180 ENSG00000136997 ENSG00000115361 ENSG00000124523 ENSG00000036473 ENSG00000164708 ENSG00000089163 ENSG00000146701 ENSG00000115419 PMC9454445__F2 Nicotinamide Adenine Dinucleotide (NAD) Metabolism as a Relevant Target in Cancer ENSG00000105835 ENSG00000123572 ENSG00000278488 ENSG00000008130 PMC3170128__F5 Innate and adaptive immune responses to cell death ENSG00000162711 ENSG00000189403 ENSG00000265972 PMC3164983__F1 mTOR inhibitors in renal cell carcinoma ENSG00000198793 ENSG00000164327 PMC4381889__F4 KRAS-reprogrammed glutamine metabolism in pancreatic cancer.Notes: In KRAS-mutant pancreatic cancer, mitochondrial glutamine flux is reprogrammed to predominantly flux through GOT2, instead of the canonical GLUD1 pathway ENSG00000125166 ENSG00000065833 ENSG00000082212 PMC11897528__F2 Lipid metabolism in GBM cells ENSG00000130164 ENSG00000197977 ENSG00000146648 PMC4818529__F1 The comparison of different biosynthetic pathways for propane production ENSG00000026103 PMC5344790__F1 Metabolic interactions with cancer epigenetics ENSG00000099810 ENSG00000133027 PMC6477784__F1 The inflammasome as a gear or cogwheel that couples purinergic signaling with the complement cascade (ComC) in the process of HSPC mobilization ENSG00000125538 ENSG00000189403 PMC4381889__F1 NADPH production from the oxidative PPP and one-carbon serine catabolism pathway.Notes: Oxidative PPP uses glucose to generate NADPH via G6PD and 6PGD ENSG00000105835 ENSG00000078237 ENSG00000008130 PMC7838852__F1 Diversity and versatility of p38 kinase signalling in health and disease ENSG00000291603 PMC7838852__F3 Diversity and versatility of p38 kinase signalling in health and disease ENSG00000177169 ENSG00000135482 ENSG00000137275 ENSG00000105550 ENSG00000116717 ENSG00000131095 ENSG00000177733 ENSG00000076053 ENSG00000100146 ENSG00000124762 ENSG00000142166 ENSG00000009709 ENSG00000111537 ENSG00000159216 ENSG00000005893 ENSG00000125538 ENSG00000113360 PMC6477784__F3 The interplay between purinergic signaling and ComC activation during mobilization of HSPCs ENSG00000163220 ENSG00000189403 ENSG00000137841 PMC11897528__F5 Double-edged sword of metabolic reprogramming in GBM, showing the balance between resistance mechanisms and therapeutic vulnerability ENSG00000104856 ENSG00000148346 ENSG00000178035 ENSG00000167468 ENSG00000169710 ENSG00000159399 PMC8306223__F2 Updating of Biological Functions of Methyltransferase SETDB1 and Its Relevance in Lung Cancer and Mesothelioma ENSG00000182718 ENSG00000125740 ENSG00000143379 PMC11936992__F3 AMPK regulates the mechanism of action of FNIP1 ENSG00000123240 ENSG00000112561 ENSG00000217128 PMC11936992__F5 Interaction of FNIP1 with autophagy ENSG00000122180 ENSG00000140262 ENSG00000078814 ENSG00000108700 ENSG00000217128 PMC11936992__F6 Action of FNIP1 in causing cancer ENSG00000163914 ENSG00000052795 ENSG00000112561 ENSG00000217128 ENSG00000146648 PMC6271242__F1 The PI3K signaling pathway and sides of action PI3K/Akt/mTOR pathway inhibitors ENSG00000186716 ENSG00000164327 ENSG00000167965 ENSG00000198286 PMC5523860__F7 HAND2 Target Gene Regulatory Networks Control Atrioventricular Canal and Cardiac Valve Development ENSG00000170961 ENSG00000124216 ENSG00000125398 ENSG00000122691 ENSG00000164107 ENSG00000163132 ENSG00000197451 PMC8617296__F9 Quercetin therapeutic targets for Alzheimer disease and type 2 diabetes mellitus ENSG00000177606 ENSG00000112715 ENSG00000146648 PMC12077450__F2 CysLTs in lung injury ENSG00000137033 ENSG00000197971 ENSG00000189403 ENSG00000166090 ENSG00000121053 PMC4338749__F1 Drugs that inhibit folding or disposal of misfolded proteins ENSG00000094631 PMC8581318__F10 SC66 inhibits the proliferation and induces apoptosis of human bladder cancer cells by targeting the AKT/B‐catenin pathway ENSG00000134982 ENSG00000168036 PMC6480217__F7 Hypothetical scheme of CA action in mammalian cells ENSG00000128272 ENSG00000144895 ENSG00000101255 ENSG00000198074 ENSG00000070669 ENSG00000079999 PMC4197569__F2 Proposed model for autophagy that implicates PLD ENSG00000129219 ENSG00000198793 ENSG00000168036 PMC7442051__F1 Mechanism of autophagy ENSG00000177169 ENSG00000198793 ENSG00000145782 ENSG00000113734 ENSG00000057663 PMC6742496__F7 Proposed Model - LPCAT1 Links Genetic Alterations of Key Components of the Growth Factor Receptor Machinery with Plasma Membrane Remodeling to Drive Tumor Growth, Generating an Actionable Dependency across Cancers ENSG00000173599 ENSG00000153395 ENSG00000146648 PMC7442051__F2 Figure depicts the autophagy regulators in regard to lung injury ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000113734 ENSG00000057663 PMC3934442__F5 Rho/Rho-Associated Coiled-Coil Forming Kinase Pathway as Therapeutic Targets for Statins in Atherosclerosis ENSG00000067900 PMC2633249__F3 Enzymatic function of multiple origins regulates the progression of colorectal cancer and the development of metastases ENSG00000002330 ENSG00000159461 PMC9068331__F2 Shared Etiology in Autism Spectrum Disorder and Epilepsy with Functional Disability ENSG00000157404 ENSG00000163914 ENSG00000155792 ENSG00000255690 PMC9675141__F6 Antioxidant and anti-inflammatory activities of Centratherum anthelminticum (L.) Kuntze seed oil in diabetic nephropathy via modulation of Nrf-2/HO-1 and NFKB pathway ENSG00000079999 PMC5118085__F1 Notch signaling and alloreactivity ENSG00000148400 ENSG00000074181 ENSG00000137845 PMC9032508__F6 Metabolic Stress and Mitochondrial Dysfunction in Ataxia-Telangiectasia ENSG00000166278 PMC3365799__F13 Major steroidogenic pathways in the three zones of the human adrenal cortex ENSG00000127948 PMC5089941__F1 Mechanism of appetite regulation by the hypothalamus and peripheral tissues ENSG00000115138 ENSG00000170893 ENSG00000166603 ENSG00000131096 PMC3660828__F3 Components involved in translocation of phospholipids to and within mitochondria of yeast ENSG00000215021 ENSG00000163624 ENSG00000087157 ENSG00000173599 ENSG00000184207 ENSG00000262145 PMC9032508__F2 Metabolic Stress and Mitochondrial Dysfunction in Ataxia-Telangiectasia ENSG00000149311 PMC12154365__F6 Dual functions of EBF1 and its molecular regulatory network across multiple tumor types ENSG00000135547 ENSG00000138757 ENSG00000166147 PMC3383335__F2 SnoN Signaling in Proliferating Cells and Postmitotic Neurons ENSG00000134982 ENSG00000150907 ENSG00000077279 PMC12154365__F4 EBF1-mediated oncogenic mechanisms and regulatory network in BCa ENSG00000175745 ENSG00000162444 PMC6521028__F8 Mechanism of PDCoV N protein interfered with the type I IFN response ENSG00000088888 ENSG00000131323 ENSG00000276561 PMC2936760__F5 Signaling pathways described in ARPE19 cells ENSG00000135218 PMC6500894__F2 Mesenchymal stem cells and their mitochondrial transfer: a double-edged sword ENSG00000178860 ENSG00000185215 PMC3660828__F2 Biosynthetic pathways of aminoglycerophospholipids ENSG00000173599 ENSG00000133027 PMC4002809__F2 Current model for NFKB signaling pathway induced by C-type lectin receptors ENSG00000187796 ENSG00000197943 PMC8346978__F2 Molecular Pathogenesis of Psoriasis and Biomarkers Reflecting Disease Activity ENSG00000149311 ENSG00000162711 ENSG00000108691 ENSG00000121807 PMC270001__F2 Chemoresistance in Human Ovarian Cancer Cells ENSG00000135446 ENSG00000105810 ENSG00000026103 PMC2907250__F1 The three top ranked pathways in this study.‘Syndecan-1-mediated signaling events’ from PID; (B) ‘Signaling of hepatocyte growth factor (c-Met)’ from BioCarta; (C) ‘Growth hormone signaling pathways’ from BioCarta ENSG00000147044 ENSG00000019991 ENSG00000042832 ENSG00000177606 ENSG00000173083 ENSG00000179295 PMC7016889__F1 General view of glycolysis ENSG00000015285 PMC3729218__F4 Mutations causing susceptibility to intestinal inflammation ENSG00000239732 ENSG00000109321 ENSG00000124882 ENSG00000100219 ENSG00000146648 ENSG00000293532 ENSG00000181704 PMC8997157__F4 PI3K/AKT Signaling Tips the Balance of Cytoskeletal Forces for Cancer Progression ENSG00000070831 PMC6186653__F2 Schematic diagram showing both the pathway for VEGF upregulation though EGFR/ALK gene alteration and its immunosuppressive role ENSG00000198793 ENSG00000146648 PMC10377462__F10 Molecular Basis of Transglutaminase-2 and Muscarinic Cholinergic Receptors in Experimental Myopia: A Target for Myopia Treatment ENSG00000125780 ENSG00000180210 ENSG00000065978 ENSG00000149968 ENSG00000153094 ENSG00000138798 ENSG00000196639 PMC6016172__F2 Pathway linked to ER stress ENSG00000128272 ENSG00000169047 PMC11063913__F1 Regulatory mechanisms of cytokines in male sex determination in mice ENSG00000104899 ENSG00000125398 ENSG00000168066 ENSG00000137090 ENSG00000285109 ENSG00000005513 ENSG00000102678 PMC12059313__F8 Isobutyrate confers resistance to inflammatory bowel disease through host–microbiota interactions in pigs ENSG00000162711 ENSG00000172936 ENSG00000049768 ENSG00000106546 PMC2833311__F6 Signaling pathways involved in Alpha-TEA-induced apoptosis in human ovarian cancer cell lines ENSG00000065361 ENSG00000026103 PMC6471306__F1 Type I and III interferon production following pathogen sensing ENSG00000213928 ENSG00000115415 ENSG00000185436 ENSG00000276561 ENSG00000142166 PMC3292751__F3 Regulation of mammalian mitophagy ENSG00000175193 ENSG00000116688 ENSG00000171109 PMC4249724__F4 Müller glia cell reprogramming and retina regeneration ENSG00000113070 ENSG00000168036 ENSG00000168610 PMC317036__F5 Model showing the possible relationship of dTOR with the insulin pathway PMC4490668__F1 Multifactorial pathogenesis of primary Sjögren’s syndrome: interferons as culprits in the self-amplifying pathogenic loop ENSG00000138385 ENSG00000116747 PMC11063913__F2 Regulatory mechanisms of WT1 in sex differentiation ENSG00000104899 ENSG00000125398 ENSG00000168066 ENSG00000070831 ENSG00000163914 PMC11063913__F4 Regulatory mechanisms of SOX9 in sex differentiation ENSG00000125398 ENSG00000102678 PMC8076851__F4 Asperuloside Enhances Taste Perception and Prevents Weight Gain in High-Fat Fed Mice ENSG00000169962 ENSG00000179002 ENSG00000135218 ENSG00000126266 ENSG00000115138 ENSG00000070985 ENSG00000137841 PMC11063913__F5 Graphical summary During sex determination in the male embryo, the expression of numerous cytokines at specific times and spaces act together to regulate the lineage differentiation of Sertoli cells ENSG00000104899 ENSG00000125398 ENSG00000168066 ENSG00000137090 ENSG00000285109 ENSG00000096088 ENSG00000102678 PMC9587054__F4 Correction To: Signaling pathways in obesity: mechanisms and therapeutic interventions ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000185269 ENSG00000168610 ENSG00000171604 ENSG00000130703 ENSG00000087274 PMC9603842__F4 Use of Retinoids for the Prevention and Treatment of Skin Cancers: An Updated Review ENSG00000168040 ENSG00000168610 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC9587054__F5 Correction To: Signaling pathways in obesity: mechanisms and therapeutic interventions ENSG00000115138 ENSG00000169710 ENSG00000096717 PMC6909968__F6 Proposed schematic model illustrating the role of SLCO4A1-AS1 in regulating CRC by EGFR/MAPK signaling pathway ENSG00000157764 ENSG00000095015 ENSG00000146648 PMC9587054__F6 Correction To: Signaling pathways in obesity: mechanisms and therapeutic interventions ENSG00000185231 ENSG00000198576 ENSG00000115138 ENSG00000124089 ENSG00000166603 ENSG00000131096 PMC11628531__F1 LAG-3 signaling pathway and its ligands in tumor immunity ENSG00000089692 ENSG00000134982 ENSG00000104760 ENSG00000137845 PMC9587054__F3 Correction To: Signaling pathways in obesity: mechanisms and therapeutic interventions ENSG00000187871 ENSG00000115138 ENSG00000096088 ENSG00000184344 ENSG00000130513 PMC9243884__F3 IL-1 family of cytokines and receptors in pathogenesis of COVID-19 ENSG00000122218 ENSG00000137033 PMC9256571__F1 Challenges and opportunities in achieving effective regulatory T cell therapy in autoimmune liver disease ENSG00000169248 ENSG00000169245 ENSG00000186810 ENSG00000102962 ENSG00000131142 ENSG00000161921 ENSG00000138755 ENSG00000115009 ENSG00000112486 PMC4078240__F4 Map of SCAP/SREBP Transcriptional Control of Cholesterol and FA Biosynthesis ENSG00000131473 ENSG00000160752 ENSG00000119915 ENSG00000112972 ENSG00000186480 ENSG00000169710 ENSG00000099194 ENSG00000076555 PMC8301368__F7 Platelet-Activating Factor Acetylhydrolase Expression in BRCA1 Mutant Ovarian Cancer as a Protective Factor and Potential Negative Regulator of the Wnt Signaling Pathway ENSG00000012048 ENSG00000168036 PMC8301368__F8 Platelet-Activating Factor Acetylhydrolase Expression in BRCA1 Mutant Ovarian Cancer as a Protective Factor and Potential Negative Regulator of the Wnt Signaling Pathway ENSG00000087245 ENSG00000291971 ENSG00000100985 PMC8648465__F7 Network Pharmacology-Based Analysis of the Underlying Mechanism of Hyssopus cuspidatus Boriss. for Antiasthma: A Characteristic Medicinal Material in Xinjiang ENSG00000102871 ENSG00000177606 ENSG00000157601 PMC7003858__F4 Signaling in T‐cell activation and PD‐1–mediated suppression ENSG00000291603 ENSG00000134982 ENSG00000113263 PMC9298327__F1 Expression, prognostic significance and therapeutic implications of PD‐L1 in gliomas ENSG00000089692 ENSG00000291603 ENSG00000134982 PMC6621970__F10 Schematic highlighting the signaling cascades that are dependent on erbB4 in MPNSTs ENSG00000198793 ENSG00000115904 ENSG00000168610 ENSG00000178568 PMC3718675__F3 Axis of ageing: telomeres, p53 and mitochondria ENSG00000182511 ENSG00000198793 ENSG00000096717 PMC3524155__F1 Sensing the enemy ENSG00000167207 ENSG00000106100 PMC8099789__F1 ACE2 Down-Regulation May Act as a Transient Molecular Disease Causing RAAS Dysregulation and Tissue Damage in the Microcirculatory Environment Among COVID-19 Patients ENSG00000175054 ENSG00000130234 ENSG00000122194 PMC2594010__F2 Regulation of metastasis in colorectal adenocarcinoma: A collision between development and tumor biology ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000125084 PMC3932427__F1 Schematic showing the interference of Hepatitis C virus in the insulin signaling pathway ENSG00000198793 PMC5367255__F8 Model depicting role of miR-432 in regulating myogenesis ENSG00000122180 ENSG00000112242 ENSG00000198793 PMC7922006__F8 CASR-ROCK-YAP1 signaling pathway in tumor parathyroid cells ENSG00000150457 ENSG00000036828 ENSG00000131023 PMC3131157__F6 Manipulation of plant cell ubiquitin pathway by bacterial pathogens ENSG00000100422 PMC6652118__F1 RIG-I/MDA5 signaling pathway RIG-I and MDA5 are first activated by recognition of PAMP dsRNA, which causes them to interact with MAVS ENSG00000183735 ENSG00000088888 ENSG00000276561 ENSG00000184216 PMC9520222__AF1 Ion elemental-optimized layered double hydroxide nanoparticles promote chondrogenic differentiation and intervertebral disc regeneration of mesenchymal stem cells through focal adhesion signaling pathway ENSG00000125398 ENSG00000070831 ENSG00000291748 ENSG00000108821 PMC7317989__F1 Model illustrating the steps of EBV infection of epithelial cells ENSG00000142627 ENSG00000117322 PMC7553088__F4 Chemokine-like factor 1: A promising therapeutic target in human diseases ENSG00000162692 PMC7553088__F5 Chemokine-like factor 1: A promising therapeutic target in human diseases ENSG00000136997 ENSG00000168610 PMC6886211__F8 PLNet2: LocPL pathway reconstructions (first 100 paths) ENSG00000157404 ENSG00000142192 ENSG00000291971 ENSG00000125733 ENSG00000187266 ENSG00000105639 ENSG00000168610 ENSG00000010671 ENSG00000160691 ENSG00000179295 ENSG00000066468 ENSG00000110395 ENSG00000105397 ENSG00000078747 ENSG00000010810 ENSG00000123609 ENSG00000004897 ENSG00000146648 ENSG00000140443 PMC9409040__F7 Multi-Level Control of the ATM/ATR-CHK1 Axis by the Transcription Factor E4F1 in Triple-Negative Breast Cancer ENSG00000149311 ENSG00000175054 ENSG00000167967 ENSG00000149554 ENSG00000011485 PMC2153443__F8 TGFB SIGNALING BY PROINFLAMMATORY CYTOKINES IN ARTICULAR CHONDROCYTES ENSG00000125538 PMC7154099__F1 Schematic diagram depicting the regulation of osteoblastic-specific genes expression by lithium through activation of three major signaling pathways, including the canonical Wnt/Beta-catenin, PI3K/Akt and BMP-2 signaling pathways ENSG00000170365 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000168036 ENSG00000131196 PMC8394324__F3 Enzymatic Metabolism of Flavonoids by Gut Microbiota and Its Impact on Gastrointestinal Cancer ENSG00000120868 ENSG00000168040 ENSG00000026103 PMC7228650__F2 Epigenetics of colorectal cancer: biomarker and therapeutic potential ENSG00000137673 ENSG00000162337 ENSG00000134982 ENSG00000138798 ENSG00000136997 ENSG00000168036 ENSG00000146648 PMC8394324__F4 Enzymatic Metabolism of Flavonoids by Gut Microbiota and Its Impact on Gastrointestinal Cancer PMC10987302__F1 Crosstalk between lncRNAs and Wnt/Beta-catenin signaling pathways in lung cancers: From cancer progression to therapeutic response ENSG00000124766 ENSG00000168036 ENSG00000189403 ENSG00000134245 ENSG00000168646 PMC4522946__F6 Apoptotic signaling pathway induced by Licochalcone-A in head and neck squamous carcinoma FaDu cells ENSG00000002330 ENSG00000171791 ENSG00000168040 PMC10487929__F9 Network connectivity pathway map of the downstream effects of simulated SARS-CoV-2 infection on the predicted activity of the NISP ENSG00000108691 ENSG00000111537 ENSG00000115415 ENSG00000130234 ENSG00000125538 ENSG00000277263 ENSG00000073756 ENSG00000276561 PMC4447643__F9 Schematic diagram showing the modulation of insulin-mediated glucose uptake in muscle cells by CRFR2 signaling pathway ENSG00000169047 ENSG00000198793 PMC4238866__F10 Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae ENSG00000196511 ENSG00000278494 ENSG00000179632 PMC4298491__F2 PI3K in the biology of B cells ENSG00000177455 ENSG00000007312 ENSG00000186716 ENSG00000198793 ENSG00000197943 ENSG00000010671 PMC4298491__F3 Signalling of the PI3K/AKT/mTOR pathway and relevant drugs that target each of the components of the pathway ENSG00000186716 ENSG00000146648 PMC10487929__F6 Influence of COVID-19 on SNCA expression and PD ENSG00000110711 ENSG00000187608 ENSG00000147434 ENSG00000157601 ENSG00000073756 ENSG00000276561 ENSG00000008056 ENSG00000019582 ENSG00000138207 ENSG00000108691 ENSG00000111537 ENSG00000134321 ENSG00000188313 ENSG00000115415 ENSG00000130234 ENSG00000125538 ENSG00000277263 ENSG00000134121 ENSG00000125968 ENSG00000134531 PMC10487929__F7 Network connectivity pathway map of ACE2’s downstream effects of simulated SARS-CoV-2 infection on predicted activity of SNCA and PD ENSG00000111537 ENSG00000130234 ENSG00000125538 PMC10545783__F1 Bacterial PSAs transduce signals through innate receptors to modulate immune responses ENSG00000174125 ENSG00000172936 ENSG00000136869 PMC8073160__F4 Potential of FGF-2 in Craniofacial Bone Tissue Engineering: A Review ENSG00000118972 ENSG00000167941 PMC8073160__F1 Potential of FGF-2 in Craniofacial Bone Tissue Engineering: A Review ENSG00000178860 ENSG00000152266 ENSG00000167941 PMC4710174__F1 HSC aging and senescent immune remodeling ENSG00000107562 ENSG00000070831 ENSG00000182568 ENSG00000168036 PMC2151350__F2 Model for renal pathology in Dent's disease (due to a loss of ClC-5) The small peptide PTH (parathyroid hormone) and various forms of vitamin D (VitD; bound to their binding protein) pass the glomerular filter into the early proximal tubule (A) ENSG00000152266 ENSG00000274348 PMC6623175__F9 Model proposed to explain why BDNF fails to regulate local translation in the hippocampus of Ts1Cje mice ENSG00000106683 ENSG00000010810 ENSG00000198793 ENSG00000198576 ENSG00000122194 ENSG00000291561 ENSG00000103942 PMC9692093__F2 RNA modification in the generation of acquired drug resistance in glioma ENSG00000125285 ENSG00000133937 ENSG00000136997 ENSG00000183579 ENSG00000196743 ENSG00000160710 ENSG00000136231 PMC4704338__F1 Activation of the Notch signaling pathway ENSG00000138798 ENSG00000140443 PMC2649208__F2 Molecular interaction map displaying the functional interaction of genes in the MEK/ERK output profile with established roles in ERK signaling ENSG00000136158 ENSG00000110395 ENSG00000120875 ENSG00000244405 ENSG00000175832 ENSG00000136997 ENSG00000175592 ENSG00000173846 ENSG00000187678 PMC6966515__F2 Schematic showing the numerous cellular events which are altered by viral proteins in transformed cells (see key bottom right corner) ENSG00000070831 ENSG00000134982 ENSG00000198793 ENSG00000163914 ENSG00000168040 ENSG00000117399 PMC1599931__F1 Phosphatidylinositide 3′-OH kinase/Akt/mTOR signaling pathway PMC3228224__F1 Pathways involved in mTOR signaling.Abbreviations: mTOR, mammalian target of rapamycin; PI3K, phosphoinositide 3-kinase; TSC, tuberous sclerosis.Adapted from: Kopelovich L, Fay JR, Sigman CC, Crowell JA ENSG00000198793 PMC4793911__F2 Major cellular mechanisms controlling contraction in gastrointestinal smooth muscle cells ENSG00000291507 ENSG00000253506 ENSG00000115271 PMC9505944__F2 Controversial Role of LPS in Platelet Activation In Vitro ENSG00000170458 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC514817__F2 Cytokine production by MAPK pathways ENSG00000070831 ENSG00000177606 PMC9505944__F3 Controversial Role of LPS in Platelet Activation In Vitro ENSG00000170458 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000184216 PMC7919585__F2 CoVs on mitochondrial dynamics and autophagy as a quality control axis and the regulatory effect of melatonin.Coronaviruses impacts mitochondrial dynamics and mitophagy ENSG00000152348 ENSG00000126775 ENSG00000144848 ENSG00000158828 ENSG00000145782 ENSG00000057663 ENSG00000115317 ENSG00000214253 PMC8316339__F5 Apicoplast isoprenoid biosynthesis is critical for P. falciparum survival of febrile temperatures ENSG00000185236 ENSG00000197429 ENSG00000108774 PMC514817__F4 Interaction of stress and inflammatory responses ENSG00000284774 ENSG00000177606 PMC4488779__F2 Proposed model of the vitamin D-dependent antimicrobial pathway ENSG00000174125 ENSG00000167207 ENSG00000105516 ENSG00000105697 PMC8957809__F8 Nobiletin Induces Ferroptosis in Human Skin Melanoma Cells Through the GSK3Beta-Mediated Keap1/Nrf2/HO-1 Signalling Pathway ENSG00000167468 ENSG00000079999 PMC5435544__F4A Signal transduction pathways and targets in paediatric Burkitt lymphoma ENSG00000162889 ENSG00000104365 ENSG00000115008 ENSG00000142192 ENSG00000100906 ENSG00000050748 ENSG00000169032 ENSG00000135341 ENSG00000114738 ENSG00000142166 ENSG00000185386 ENSG00000115415 ENSG00000175104 ENSG00000184216 PMC7905385__F1B Immune response, immunopathology, and mechanism of action of immunotherapeutics for SARS-CoV-2 infection (intracellular) ENSG00000115977 ENSG00000081041 ENSG00000239732 ENSG00000125538 ENSG00000184012 ENSG00000164342 PMC6014315__F1 Impact of PI3K inhibitors on breast cancer cell and its tumor microenvironment ENSG00000109452 PMC11121230__F2 SHIP1 and SHIP2 in the PI3K/AKT signaling pathway (created with BioRender ENSG00000140992 PMC5929164__F5 Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss-Driven Tumorigenesis ENSG00000186575 ENSG00000285246 ENSG00000150457 ENSG00000131023 PMC3060878__F5 FGF19 Regulates Cell Proliferation, Glucose and Bile Acid Metabolism via FGFR4-Dependent and Independent Pathways ENSG00000160867 ENSG00000105550 ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC8125511__F5 Broadly Antiviral Activities of TAP1 through Activating the TBK1-IRF3-Mediated Type I Interferon Production ENSG00000183735 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC8615865__F3 Nanoscale Sub-Compartmentalization of the Dendritic Spine Compartment PMC4839647__F3 A Balanced Tissue Composition Reveals New Metabolic and Gene Expression Markers in Prostate Cancer ENSG00000131473 ENSG00000143252 ENSG00000088826 ENSG00000073578 ENSG00000100412 ENSG00000169710 ENSG00000123505 ENSG00000172340 ENSG00000076555 ENSG00000116649 ENSG00000102172 ENSG00000062485 PMC6924635__F1 Exosome biogenesis and major exosomal cargoes ENSG00000041353 ENSG00000085117 ENSG00000110651 ENSG00000010278 ENSG00000135404 PMC7563377__F8 Model illustrates targeting of the hedgehog (Hh) signaling using PSMA aptamer conjugated PBM-NPs inhibits prostate cancer tumorigenesis ENSG00000164690 ENSG00000128602 PMC4222901__F2 Cytoskeletal modulation and signaling ENSG00000070831 ENSG00000165527 ENSG00000160293 ENSG00000146648 PMC7364818__F7 Differentially expressed genes in the PAI-1 KO injured tendon that contribute to the activation of the canonical PTEN Signaling pathway at 2-weeks post injury ENSG00000002330 ENSG00000046889 ENSG00000086015 ENSG00000164305 PMC9279758__F6 CD44 potentiates hepatocellular carcinoma migration and extrahepatic metastases via the AKT/ERK signaling CXCR4 axis ENSG00000107562 ENSG00000026508 ENSG00000121966 PMC4539069__F1 Proposed model for the complex cross talk between various receptors and mediators in early phase response in allergic rhinitis ENSG00000183625 ENSG00000121807 ENSG00000196689 PMC3693108__F1 Therapeutic molecular targets for endometrial cancer ENSG00000066468 ENSG00000198793 ENSG00000146648 PMC6077868__F7 TGFB-dependent signaling implicated in fibrosis process ENSG00000198793 PMC3162305__F4 Oncostatin M signaling pathway ENSG00000100234 ENSG00000145623 ENSG00000099985 ENSG00000125148 ENSG00000111837 PMC2533092__F1 Metabolic pathways for the synthesis of phospholipids and neutral lipid classes in S ENSG00000163624 ENSG00000173599 ENSG00000166123 PMC3648340__F1 Iron and Diabetes Risk ENSG00000010704 ENSG00000182511 ENSG00000089472 ENSG00000106327 PMC3571654__F1 shows the effects of osteoblast-secreted osteocalcin on glucose homeostasis and its novel role in regulating testosterone production in the leydig cells ENSG00000128272 PMC6034278__F5 LTR-retrotransposon transcriptome modulation in response to endotoxin-induced stress in PBMCs ENSG00000137965 ENSG00000163661 ENSG00000276561 ENSG00000137959 PMC126023__F7 Endogenous DNA abasic sites cause cell death in the absence of Apn1, Apn2 and Rad1/Rad10 in Saccharomyces cerevisiae ENSG00000113456 PMC3258305__F2 The Long History of Iron in the Universe and in Health and Disease ENSG00000115107 PMC11003173__F10 Hypothetical modules and cold response pathways of eggplant ENSG00000105722 ENSG00000110395 PMC9086029__F6 Microarray expression profile and bioinformatic analysis of circular RNA in human esophageal carcinoma ENSG00000115484 ENSG00000119737 ENSG00000129932 ENSG00000153914 ENSG00000265972 ENSG00000179456 ENSG00000241644 ENSG00000179364 ENSG00000164237 ENSG00000168488 ENSG00000108821 ENSG00000271425 ENSG00000115561 ENSG00000189306 ENSG00000015153 ENSG00000136938 ENSG00000173610 ENSG00000150637 ENSG00000127585 ENSG00000070367 ENSG00000197013 ENSG00000164291 ENSG00000155975 ENSG00000182240 ENSG00000164855 ENSG00000166435 ENSG00000150394 ENSG00000089050 ENSG00000169519 ENSG00000120289 ENSG00000145685 ENSG00000173334 ENSG00000100372 ENSG00000145247 ENSG00000265763 ENSG00000198839 ENSG00000167554 ENSG00000187239 ENSG00000198053 ENSG00000123992 ENSG00000214694 ENSG00000198077 ENSG00000261115 ENSG00000152213 ENSG00000204977 ENSG00000179133 ENSG00000217236 ENSG00000130943 ENSG00000139675 ENSG00000063587 ENSG00000188039 ENSG00000163792 ENSG00000166822 ENSG00000048740 ENSG00000131043 ENSG00000263155 ENSG00000117472 ENSG00000197714 ENSG00000155858 ENSG00000108828 ENSG00000139926 ENSG00000086758 ENSG00000160445 ENSG00000111801 ENSG00000015285 ENSG00000105127 PMC9086029__F7 Microarray expression profile and bioinformatic analysis of circular RNA in human esophageal carcinoma ENSG00000181472 ENSG00000004975 ENSG00000120837 ENSG00000105327 ENSG00000138449 ENSG00000005339 ENSG00000116521 ENSG00000142230 ENSG00000125384 ENSG00000198793 ENSG00000170558 ENSG00000086758 ENSG00000183850 ENSG00000111962 ENSG00000204946 ENSG00000151224 ENSG00000215472 ENSG00000063660 ENSG00000134245 ENSG00000172936 ENSG00000185591 ENSG00000276799 PMC3651307__F1 Toll-like Receptor (TLR) Signaling Pathways ENSG00000174125 ENSG00000243414 ENSG00000150455 ENSG00000127666 ENSG00000276561 ENSG00000239732 ENSG00000187554 ENSG00000263528 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC5901872__F2 Expression difference of metabolic genes between the GX stage and X stage in BSGX001 and XH7 ENSG00000006695 ENSG00000100412 ENSG00000138495 ENSG00000178741 PMC3792371__F1 TEC and MAPK Kinase Signalling Pathways in T helper (TH) cell Development, TH2 Differentiation and Allergic Asthma ENSG00000291603 ENSG00000111537 ENSG00000010810 ENSG00000113520 ENSG00000113263 ENSG00000091140 PMC9183106__F6 Nobiletin Inhibits Hypoxia-Induced Placental Damage via Modulating P53 Signaling Pathway ENSG00000171791 PMC8505060__F9 Jie-Yu-He-Huan Capsule Ameliorates Anxiety-Like Behaviours in Rats Exposed to Chronic Restraint Stress via the cAMP/PKA/CREB/BDNF Signalling Pathway PMC4766714__F9 Incomplete lung recovery following sub-acute inhalation of combustion-derived ultrafine particles in mice ENSG00000189377 ENSG00000148346 ENSG00000102962 ENSG00000151882 ENSG00000163435 ENSG00000081041 ENSG00000170458 ENSG00000163737 ENSG00000135373 ENSG00000115009 PMC3185763__F1 Extrinsic (death receptor-mediated) and intrinsic (mitochondria-mediated) pathways that lead to apoptosis of HIV infected helper T cells ENSG00000168040 ENSG00000121966 ENSG00000026103 PMC442148__F2 Protein interaction map around some selected baits in the TGFB pathway ENSG00000157933 ENSG00000123091 ENSG00000143842 ENSG00000168036 ENSG00000127022 ENSG00000113569 ENSG00000105568 ENSG00000186298 ENSG00000076604 ENSG00000185104 ENSG00000242221 ENSG00000157557 ENSG00000183283 ENSG00000198742 ENSG00000112851 ENSG00000285438 ENSG00000185591 ENSG00000118898 ENSG00000173230 PMC4589430__F2 Immunosuppressive and tumor-promoting functions of TAMs and MDSCs in HCC ENSG00000177575 ENSG00000170458 ENSG00000129226 ENSG00000168610 PMC5596246__F1 Caspases in extrinsic and intrinsic apoptosis ENSG00000102871 ENSG00000120868 ENSG00000168040 PMC5596246__F3 Caspases control the cGAS-STING signaling pathway ENSG00000183735 ENSG00000164430 PMC5596246__F4 Caspases regulate RLR and TLR antiviral signaling ENSG00000183735 ENSG00000239732 ENSG00000088888 ENSG00000137275 ENSG00000102871 ENSG00000172936 ENSG00000168040 ENSG00000121060 ENSG00000276561 ENSG00000285379 ENSG00000164342 PMC6245571__F2 Species-Specific Transcriptional Regulation of Genes Involved in Nitric Oxide Production and Arginine Metabolism in Macrophages ENSG00000168003 ENSG00000081181 ENSG00000139514 ENSG00000120280 ENSG00000118520 ENSG00000036473 ENSG00000150787 ENSG00000116096 PMC7411521__F4 Apoptotic signaling through membrane (lipids)-mediated spontaneous activation of Bax/Bak ENSG00000132906 ENSG00000100290 ENSG00000002330 ENSG00000168040 ENSG00000135116 ENSG00000064012 ENSG00000164305 ENSG00000104081 PMC3056121__F1 Regulatory natural autoantibodies to apoptotic cells: Pallbearers and protectors ENSG00000239732 ENSG00000173599 ENSG00000291368 PMC8878972__F7 Zika Virus Infection of Sertoli Cells Alters Protein Expression Involved in Activated Immune and Antiviral Response Pathways, Carbohydrate Metabolism and Cardiovascular Disease ENSG00000104812 ENSG00000189058 ENSG00000059804 ENSG00000008513 ENSG00000089127 ENSG00000087053 ENSG00000149782 ENSG00000109323 ENSG00000139219 ENSG00000170961 ENSG00000112304 ENSG00000120742 ENSG00000188313 ENSG00000140285 ENSG00000026508 ENSG00000184371 ENSG00000169429 PMC2919952__F1 Scheme of basic metabolic pathways and energy conservation in C ENSG00000150787 ENSG00000105379 PMC6589702__F8 Proposed model of regulation of endothelial barrier function by FBXW7 ENSG00000130164 ENSG00000143878 ENSG00000113161 ENSG00000104549 ENSG00000109670 PMC10502988__F8 Following CARNIVAL analysis (or re-uploading previous results) the user can carry out pathway enrichment and visualisation on the inferred signalling network ENSG00000284774 ENSG00000109906 ENSG00000173039 ENSG00000169032 ENSG00000121879 ENSG00000184481 ENSG00000066336 ENSG00000175745 ENSG00000150907 ENSG00000171608 ENSG00000146648 ENSG00000178568 ENSG00000198911 PMC5932261__F7 Mechanical strain induced phospho-proteomic signaling in uterine smooth muscle cells PMC7308544__F2 The metabolic interrelationships between low-density lipoprotein (LDL) subfractions and their hepatic precursors ENSG00000042832 PMC5522095__F8 Naoling decoction restores cognitive function by inhibiting the neuroinflammatory network in a rat model of Alzheimer’s disease ENSG00000162711 ENSG00000136869 PMC9084694__F4 Single‐cell profiling of transcriptomic changes during in vitro maturation of human oocytes ENSG00000121207 ENSG00000186517 ENSG00000129355 ENSG00000124762 ENSG00000264424 ENSG00000133216 ENSG00000066468 ENSG00000154645 ENSG00000173914 ENSG00000057704 ENSG00000197142 ENSG00000135404 ENSG00000107165 ENSG00000283060 ENSG00000127616 ENSG00000157111 PMC5243144__F4 Schematic summary of metabolic pathways disturbance caused by suppression of pyruvate carboxylase in MDA-MB-231-derived cell lines ENSG00000065833 ENSG00000173599 ENSG00000115419 ENSG00000026103 PMC6165719__F1 Signaling pathways underlying synaptic plasticity in striatal direct pathway spiny projection neuron ENSG00000123360 ENSG00000173599 PMC9084694__F2 Single‐cell profiling of transcriptomic changes during in vitro maturation of human oocytes ENSG00000130675 ENSG00000184260 ENSG00000187837 ENSG00000007171 PMC11276987__F10 Lipids as signaling molecules that regulate metabolism ENSG00000291971 ENSG00000169047 ENSG00000172936 ENSG00000136869 PMC7418812__F9 Model for glucose regulation ovarian primordial follicles activation via the AMPK/mTOR signaling pathway ENSG00000198793 ENSG00000131023 PMC4179923__F6 Tazarotene Induces Apoptosis in Human Basal Cell Carcinoma via Activation of Caspase-8/t-Bid and the Reactive Oxygen Species-Dependent Mitochondrial Pathway ENSG00000168040 ENSG00000026103 PMC2954288__F10 Hypothetical model for SWAP-70 function in mast cell FcERI signaling ENSG00000213658 ENSG00000113520 PMC5774249__F8 Cellular model of insulin (and leptin) signaling via TRPC5 channel activation in POMC neurons ENSG00000167323 ENSG00000115138 ENSG00000072315 PMC3670000__F2 Signaling pathways used by GH to regulate growth and metabolism ENSG00000115415 ENSG00000291971 ENSG00000198793 ENSG00000168610 PMC3670000__F3 Signaling pathways activated by E2 and its crosstalk with GH ENSG00000120833 ENSG00000112964 PMC4933215__F2A Short Term Hypoxia Synergizes with Interleukin 15 Priming in Driving Glycolytic Gene Transcription and Supports Human Natural Killer Cell Activities ENSG00000005339 ENSG00000109320 ENSG00000198793 ENSG00000072274 ENSG00000105647 ENSG00000171791 ENSG00000169032 ENSG00000112715 ENSG00000124762 ENSG00000187840 ENSG00000134086 ENSG00000111537 ENSG00000148660 ENSG00000100387 ENSG00000197943 ENSG00000136869 ENSG00000171608 ENSG00000145349 ENSG00000140443 PMC10948231__F2 PPARG and the PTEN-PI3K/AKT Signaling Axis May Cofunction in Promoting Chemosensitivity in Hypopharyngeal Squamous Cell Carcinoma ENSG00000117020 ENSG00000121879 ENSG00000132170 PMC5249061__F6 A Circulating microRNA Signature Predicts Age-Based Development of Lymphoma ENSG00000132541 ENSG00000177606 ENSG00000136997 PMC6770393__F2 Key metabolic remodeling and potential therapeutic targets in glioblastoma (GBM) ENSG00000067057 ENSG00000060982 ENSG00000198793 ENSG00000136997 ENSG00000146648 ENSG00000115419 ENSG00000159399 PMC5253647__F6 SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers ENSG00000087586 ENSG00000127616 PMC7550790__F1 Involvement of unfolded protein response (UPR) in neuropsychiatric disorders ENSG00000144895 ENSG00000100219 PMC2998292__F1 Estrogen and Tamoxifen Metabolic Pathways depicted at the genomic level ENSG00000082175 ENSG00000197408 PMC3851681__F1 Evaluating the potential of IL-27 as a novel therapeutic agent in HIV-1 infection ENSG00000162594 ENSG00000096996 ENSG00000105246 PMC2998292__F2 Pathway Analysis Models for the Tamoxifen (TAM) Pathway tested with data from the Placebo (P) and Tamoxifen (T) arms ENSG00000165841 ENSG00000197408 PMC6246015__F2 Signaling pathways subverted in T-cell oncogenesis ENSG00000291603 ENSG00000213658 ENSG00000010810 ENSG00000198793 ENSG00000136997 ENSG00000173039 ENSG00000171791 ENSG00000168610 ENSG00000141968 ENSG00000198286 PMC9696358__F2 Methylglyoxal in the Brain: From Glycolytic Metabolite to Signalling Molecule ENSG00000142192 ENSG00000104321 ENSG00000164305 PMC8759917__F9 Lanzhang Granules Ameliorate Nonalcoholic Fatty Liver Disease by Regulating the PPARA Signaling Pathway ENSG00000167910 ENSG00000103375 ENSG00000197977 ENSG00000125255 ENSG00000113790 PMC7870803__F10 Diagram depicting the molecular regulation mechanism of the NEAT1/miR-129-5p/PEG3 axis in liver fibrosis of mice with NASH through the NFKB signaling pathway ENSG00000198300 ENSG00000123908 PMC7143872__F1 Impact of physical activity on bone health ENSG00000167941 ENSG00000125538 PMC10242642__F1 SAMHD1 single nucleotide polymorphisms impact outcome in children with newly diagnosed acute myeloid leukemia ENSG00000162368 ENSG00000167325 ENSG00000171848 ENSG00000158825 ENSG00000100842 ENSG00000129187 PMC4622586__F1 The classical complement pathway initiated by mAbs and its inhibitors ENSG00000039537 ENSG00000196352 ENSG00000117335 ENSG00000244731 PMC8872331__F3 MicroRNA Interrelated Epithelial Mesenchymal Transition (EMT) in Glioblastoma ENSG00000134853 ENSG00000139687 ENSG00000196712 PMC8872331__F4 MicroRNA Interrelated Epithelial Mesenchymal Transition (EMT) in Glioblastoma ENSG00000100234 ENSG00000149968 ENSG00000100985 PMC9866016__F10 Alfalfa Xeno-miR168b Target CPT1A to Regulate Milk Fat Synthesis in Bovine Mammary Epithelial Cells ENSG00000157184 ENSG00000117054 ENSG00000135218 ENSG00000172216 ENSG00000115361 PMC5418219__F2 Roles and modulations of toll-interacting protein (Tollip) in acute and chronic inflammation ENSG00000134070 ENSG00000136869 PMC7604396__F1 KRAS4B domain organization and RAS signaling pathway at the cell membrane ENSG00000138798 ENSG00000115904 ENSG00000146648 PMC7313057__F1 Bone metastatisation process ENSG00000167941 ENSG00000170558 PMC7570423__F1 Immunity, endothelial injury and complement-induced coagulopathy in COVID-19 ENSG00000130234 ENSG00000184012 PMC3988238__F1 Dendritic cells initiate T cell immunity in the lymph nodes ENSG00000138378 ENSG00000107485 ENSG00000049768 ENSG00000168610 PMC3989954__F1 Crosstalk between mechanistic target of rapamycin signaling pathway and colorectal oncogenic pathways ENSG00000198793 ENSG00000163914 ENSG00000118515 ENSG00000146648 PMC7570423__F3 Immunity, endothelial injury and complement-induced coagulopathy in COVID-19 ENSG00000039537 ENSG00000113600 ENSG00000110799 ENSG00000130234 ENSG00000184012 PMC12039146__F7 Schematic diagram of lipid metabolism and its crosstalk with other metabolism pathways ENSG00000145431 ENSG00000042832 ENSG00000288174 ENSG00000198793 ENSG00000052795 ENSG00000169710 ENSG00000124253 ENSG00000275544 ENSG00000159399 ENSG00000062282 PMC8155903__F5 Differential mRNA and miRNA Profiles Reveal the Potential Roles of Genes and miRNAs Involved in LPS Infection in Chicken Macrophages ENSG00000239732 ENSG00000170458 ENSG00000136997 ENSG00000168040 ENSG00000150455 ENSG00000164342 PMC11486635__F5 IRFs Respond to TLR Signaling and Participate in the Expression and Function of IFNs ENSG00000159128 ENSG00000213928 ENSG00000140968 ENSG00000139370 ENSG00000185436 ENSG00000027697 ENSG00000150455 ENSG00000125347 ENSG00000276561 ENSG00000142166 ENSG00000169245 ENSG00000183735 ENSG00000105397 ENSG00000120280 ENSG00000115415 ENSG00000137265 ENSG00000147896 ENSG00000172936 ENSG00000168310 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC9201425__F3 Antimicrobial Peptide Expression at the Ocular Surface and Their Therapeutic Use in the Treatment of Microbial Keratitis ENSG00000170458 ENSG00000175104 ENSG00000146648 PMC11486635__F3 Apoptosis by IRFs ENSG00000159128 ENSG00000027697 ENSG00000168040 ENSG00000154124 ENSG00000127191 ENSG00000125347 ENSG00000276561 ENSG00000142166 ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000137265 ENSG00000131323 ENSG00000120868 ENSG00000175104 PMC4386406__F2 The phosphoproteomics data ENSG00000002330 ENSG00000213658 ENSG00000070831 ENSG00000109320 ENSG00000198793 ENSG00000115904 ENSG00000113263 ENSG00000124181 ENSG00000141968 ENSG00000160691 PMC11035723__F1 Early dynamic changes to monocytes following major surgery are associated with subsequent infections ENSG00000163599 ENSG00000121807 ENSG00000168685 PMC4925820__F4 The hunger signaling pathway constructed in the IPA program colored according to genes correlating with circulating leptin levels ENSG00000131096 PMC4925820__F6 Genes involved in circadian rhythm pathway constructed in the IPA program colored according their correlation with circulating levels of tumor necrosis factor alpha (TNFA) ENSG00000132938 ENSG00000167074 ENSG00000169710 ENSG00000162772 ENSG00000069667 ENSG00000132170 ENSG00000128272 ENSG00000084676 ENSG00000143815 ENSG00000156127 ENSG00000153879 ENSG00000177606 ENSG00000242866 ENSG00000132326 ENSG00000197386 ENSG00000104918 ENSG00000092067 ENSG00000205758 ENSG00000054118 ENSG00000185149 PMC4741457__F9 Structural basis for the indispensable role of a unique zinc finger motif in LNX2 ubiquitination ENSG00000136997 ENSG00000139517 ENSG00000168036 ENSG00000133961 ENSG00000168646 PMC4480235__F5 Signaling by myeloid C-type lectin receptors in immunity and homeostasis ENSG00000141068 PMC10894496__F8 Optimized New Shengmai Powder modulation of cAMP/Rap1A signaling pathway attenuates myocardial fibrosis in heart failure ENSG00000168610 PMC8992440__F1 Cellular irinotecan resistance in colorectal cancer and overcoming irinotecan refractoriness through various combination trials including DNA methyltransferase inhibitors: a review ENSG00000134982 ENSG00000118777 ENSG00000023839 PMC6309125__F1 Hippo Pathway and its canonical upstream regulators ENSG00000129474 ENSG00000101265 ENSG00000197905 ENSG00000139926 ENSG00000114978 ENSG00000007866 ENSG00000074219 ENSG00000068028 ENSG00000083857 ENSG00000179431 ENSG00000107551 ENSG00000165323 ENSG00000169435 PMC5095301__F7 Schematic diagram illustrating inhibition of HMGB1-TLR4 signaling pathway by dexamethasone in renal ischemia reperfusion injury ENSG00000125538 ENSG00000189403 ENSG00000136869 PMC6309125__F2 KIBRA/Hippo pathway as a shunt of stressful input ENSG00000129474 ENSG00000100151 ENSG00000163914 ENSG00000114978 PMC4480235__F2 Signaling by myeloid C-type lectin receptors in immunity and homeostasis ENSG00000104856 ENSG00000162711 ENSG00000187796 ENSG00000125538 ENSG00000122877 PMC9605584__F1 DPP3: From biomarker to therapeutic target of cardiovascular diseases ENSG00000254986 ENSG00000181019 ENSG00000130234 PMC11853993__F7 CD73 downregulated expression induced by TgROP18 and its consequences on dMφ dysfunction ENSG00000118520 PMC8561419__F3 Prenatal inflammation as a link between placental expression signature of tryptophan metabolism and preterm birth ENSG00000110514 ENSG00000150787 PMC5282447__F2 Summary diagram of JAK/STAT and MAPK signal transduction ENSG00000242689 ENSG00000122756 ENSG00000184524 ENSG00000113070 ENSG00000138798 ENSG00000131095 ENSG00000160691 PMC3464875__F7 Signaling involved in MUC4 expression upon Nicotine, IFNG and Retinoic acid stimulation ENSG00000115415 ENSG00000168610 PMC9688160__F1 Crosstalk between the Hippo Pathway and the Wnt Pathway in Huntington’s Disease and Other Neurodegenerative Disorders ENSG00000167601 ENSG00000104814 ENSG00000011566 ENSG00000291971 ENSG00000163914 ENSG00000197905 ENSG00000168067 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC4631799__F2 ERBB signaling pathway is highly activated in AA PCa specimens ENSG00000002330 ENSG00000291971 ENSG00000138798 ENSG00000113070 ENSG00000198793 ENSG00000123104 ENSG00000132478 ENSG00000169291 ENSG00000115415 ENSG00000163235 ENSG00000177606 ENSG00000136997 ENSG00000178568 PMC4791944__F1 Longevity: Mapping the path to a longer life ENSG00000171105 ENSG00000140443 PMC9688160__F4 Crosstalk between the Hippo Pathway and the Wnt Pathway in Huntington’s Disease and Other Neurodegenerative Disorders ENSG00000198670 ENSG00000131023 PMC2912833__F4 Generation of a biological network of genes of the most significant Canonical Pathways for the Il10-/- (EF·CIF vs ENSG00000130304 ENSG00000150782 ENSG00000128272 ENSG00000170458 ENSG00000115415 ENSG00000276051 ENSG00000232326 ENSG00000273686 ENSG00000143226 PMC9688160__F2 Crosstalk between the Hippo Pathway and the Wnt Pathway in Huntington’s Disease and Other Neurodegenerative Disorders ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000197905 ENSG00000168036 ENSG00000007866 ENSG00000185269 ENSG00000074219 PMC3580589__F3 PTHrP signaling pathways during endochondral ossification ENSG00000163930 ENSG00000020633 ENSG00000163501 PMC9688160__F3 Crosstalk between the Hippo Pathway and the Wnt Pathway in Huntington’s Disease and Other Neurodegenerative Disorders ENSG00000167601 ENSG00000104814 ENSG00000011566 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000197386 ENSG00000168036 ENSG00000168067 ENSG00000150457 ENSG00000131023 PMC3095674__F4 Procarcinogenic Effects of Cyclosporine A are Mediated through the Activation of TAK1/TAB1 Signaling Pathway ENSG00000130159 ENSG00000171791 ENSG00000175104 ENSG00000157005 PMC2912833__F3 Generation of a biological network of genes of the most significant Canonical Pathways for the EF·CIF (Il10-/- vs ENSG00000100060 ENSG00000125347 PMC4286424__F2 Signal transduction pathway of bitter (T2R), sweet (T1R2/3), and umami (T1R1/3) GPCRs in type II taste cells of the tongue ENSG00000185933 ENSG00000070985 ENSG00000137841 PMC10558709__F7 The main findings on HMEC-1 ENSG00000147162 ENSG00000181019 ENSG00000198408 PMC3551738__F3 Network analysis of known SLE-associated genes ENSG00000153064 ENSG00000150337 ENSG00000166278 ENSG00000143226 ENSG00000185651 ENSG00000132693 ENSG00000236625 ENSG00000203747 ENSG00000173369 ENSG00000138378 ENSG00000072694 ENSG00000173372 ENSG00000105397 ENSG00000118503 ENSG00000175104 ENSG00000184216 PMC4424084__F1 RIG-I signaling pathway ENSG00000183735 ENSG00000088888 ENSG00000102871 ENSG00000121060 ENSG00000101695 PMC11829561__F4 Metabolic reprogramming in the tumor microenvironment PMC9515385__F11 Scheme depicting the relevance of the PGD2 pathway in AD and its potential as an AD therapeutic target demonstrated by timapiprant (TIMA), a DP2 antagonist ENSG00000198793 PMC5214989__F2 Mitonuclear gene groups associated with disease in GWAS are significantly enriched for protein–protein interactions ENSG00000072274 ENSG00000186480 ENSG00000171791 ENSG00000166147 ENSG00000120254 ENSG00000165733 ENSG00000100347 ENSG00000100219 ENSG00000145362 ENSG00000133083 ENSG00000166441 ENSG00000164904 ENSG00000143878 ENSG00000285250 ENSG00000143353 ENSG00000189283 ENSG00000134824 ENSG00000160223 ENSG00000167468 ENSG00000084092 ENSG00000178568 ENSG00000173334 ENSG00000002330 ENSG00000214113 ENSG00000153094 ENSG00000166260 ENSG00000197746 ENSG00000133687 ENSG00000112715 ENSG00000136381 ENSG00000104435 ENSG00000197971 ENSG00000288141 ENSG00000175110 ENSG00000119912 ENSG00000111540 ENSG00000091140 ENSG00000127838 ENSG00000154743 ENSG00000163626 ENSG00000027075 ENSG00000165644 ENSG00000125834 ENSG00000130204 ENSG00000197208 ENSG00000291973 ENSG00000016082 ENSG00000149311 ENSG00000154856 ENSG00000155287 ENSG00000170855 ENSG00000164362 ENSG00000072110 ENSG00000164398 ENSG00000243927 ENSG00000122971 ENSG00000116761 PMC2867239__F2 The Primary Cilium as a Hedgehog Signal Transduction Machine ENSG00000106571 ENSG00000164690 PMC2867239__F5 The Primary Cilium as a Hedgehog Signal Transduction Machine ENSG00000187240 ENSG00000164690 ENSG00000128602 ENSG00000281857 PMC8557709__F2 Hypothalamic endocannabinoids in obesity: an old story with new challenges ENSG00000198576 ENSG00000115138 PMC11780528__F9 Working model for the signaling pathway controlling the formation of SGs in yeast under 2-DG treatment ENSG00000228278 ENSG00000130332 ENSG00000229314 PMC2865336__F7 Role of Rad9A in the G2 decatenation checkpoint ENSG00000012048 ENSG00000175054 ENSG00000172613 ENSG00000134057 ENSG00000165392 PMC7349363__F1 Notch signalling and strategies for pharmacological targeting of this pathway ENSG00000140564 ENSG00000128917 ENSG00000114315 ENSG00000137845 PMC8233288__F2 Moonlighting of mitotic regulators in cilium disassembly ENSG00000094631 ENSG00000004975 ENSG00000166579 ENSG00000106477 ENSG00000111859 ENSG00000137601 ENSG00000171444 ENSG00000134982 ENSG00000164109 ENSG00000103540 ENSG00000078668 ENSG00000186638 ENSG00000151849 ENSG00000087586 ENSG00000143933 ENSG00000166851 ENSG00000117399 ENSG00000157240 ENSG00000105325 ENSG00000291470 ENSG00000117650 ENSG00000156970 ENSG00000112742 ENSG00000078674 PMC7997455__F1 Error-prone and error-free pathways of DNA double-strand break (DSB) repair ENSG00000143799 ENSG00000012048 ENSG00000083093 ENSG00000138346 ENSG00000051180 ENSG00000139618 PMC6523720__F1 Epigenetic mediators involved in the establishment and erasure of histone post-translational modifications and DNA methylation, as described in the text ENSG00000094631 ENSG00000171720 ENSG00000147099 ENSG00000061273 ENSG00000196591 ENSG00000048052 ENSG00000100429 ENSG00000062485 ENSG00000108840 PMC10251820__F1 Modern Management and Diagnostics in HER2+ Breast Cancer with CNS Metastasis ENSG00000002330 ENSG00000198793 ENSG00000146648 PMC3241604__F7 Proposed MAPK pathways and their inhibitors involved in EVT dysfunction during an inflammatory state ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC7754020__F8 Metabolic reprogramming of glycolysis and glutamine metabolism are key events in myofibroblast transition in systemic sclerosis pathogenesis ENSG00000105329 ENSG00000079999 PMC2832691__F3 Binding of Herpes Simplex Virus Type-1 Virions Leads to the Induction of Intracellular Signalling in the Absence of Virus Entry ENSG00000023445 ENSG00000137673 ENSG00000109320 ENSG00000291971 ENSG00000136997 ENSG00000173039 ENSG00000162924 ENSG00000166670 ENSG00000276561 PMC4647878__F4 Schematic mechanisms of action for drugs involved in the three arms of the TORAVA trial ENSG00000134086 ENSG00000115415 ENSG00000198793 ENSG00000105656 PMC3808218__F1 PI3K/Akt/mTOR pathway ENSG00000169047 ENSG00000198793 ENSG00000164327 PMC9608867__F2 Immune regulation and emerging roles of noncoding RNAs in Mycobacterium tuberculosis infection ENSG00000115415 ENSG00000112208 ENSG00000170677 ENSG00000172936 ENSG00000067900 ENSG00000175104 ENSG00000168610 PMC7279006__F1 Heme biosynthetic pathway, porphyrias and nutrients ENSG00000110711 ENSG00000066926 ENSG00000126088 ENSG00000158578 ENSG00000256269 ENSG00000188690 PMC6804961__F6 Structure establishment of three-dimensional (3D) cell culture printing model for bladder cancer ENSG00000140937 ENSG00000170558 ENSG00000198793 PMC3137974__F1 Signal pathway activation by the main TLR and CLR receptors that detect Candida ENSG00000239732 ENSG00000187796 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC8670125__F7 Proteomic and biochemical responses to different concentrations of CO2 suggest the existence of multiple carbon metabolism strategies in Phaeodactylum tricornutum ENSG00000261701 ENSG00000172005 ENSG00000036473 PMC4992436__F3 Emerging Roles for Non-canonical NFKB Signaling in the Modulation of Inflammatory Bowel Disease Pathobiology ENSG00000104856 ENSG00000142405 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000127191 PMC7895570__F1 Lipid metabolism of cancer ENSG00000131473 ENSG00000026103 PMC5118783__F3 Roles of Nanog in Cancer ENSG00000168036 ENSG00000168610 PMC7382785__F4 Illustration of aptamer involvement in cancer immunotherapy ENSG00000134982 PMC11806174__F3 Deciphering Regulatory Networks Governing Seedling Emergence in Deep-Sown Direct-Seeded Rice Cultivation ENSG00000196839 ENSG00000160710 PMC8238218__F4 Up- and down-regulated DEGs in the adenosine 3’,5’-cyclic monophosphate (cAMP) signaling pathway (map04024) between female control versus female DXM treated (FcVSFt) ENSG00000104899 ENSG00000159224 ENSG00000125398 ENSG00000157764 ENSG00000146469 ENSG00000188404 ENSG00000166592 PMC4284744__F1 Fibroblast Low-density lipoprotein (LDL)-related protein-1 (LRP-1) signaling in renal fibrogenesis ENSG00000002330 PMC12120097__F11 Exploration of the mechanism of Polyphyllin I against hepatocellular carcinoma based on network pharmacology, molecular docking and experimental validation ENSG00000281324 ENSG00000002330 ENSG00000162337 ENSG00000134982 ENSG00000111816 ENSG00000150630 PMC6071520__F5 MiRnome circulating in plasma after injury is predicted to be controlled by miRNA processing enzymes and to affect different signalling pathways ENSG00000213949 ENSG00000170558 ENSG00000100697 ENSG00000277273 ENSG00000169032 ENSG00000118971 ENSG00000128191 ENSG00000113360 ENSG00000282899 PMC2727126__F1 Noteworthy, the inhibition of this pathway through COX-inhibitors leads to induction of apoptosis and tumor growth reduction (Figure ) ENSG00000138798 PMC8510467__F5 Systematic Review of the Biological Effects of Cordycepin ENSG00000177169 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000186654 PMC11640686__F6 Chemically induced reprogramming of RPE into neural stem cells and into neurons in the brain and retina [12,27,46,93] ENSG00000198894 PMC9334758__F2 Eliciting pyroptosis to fuel cancer immunotherapy: mechanisms and strategies ENSG00000278718 ENSG00000145649 ENSG00000147697 ENSG00000073605 PMC6105724__F6 Neuropathology following treatment with NP03-lithium ENSG00000281324 ENSG00000144895 ENSG00000198793 ENSG00000168036 ENSG00000131095 ENSG00000168610 PMC3632644__F2 GLI1 Isoforms and cancer characteristics ENSG00000272398 ENSG00000164690 ENSG00000112715 PMC11640686__F5 Chemically induced reprogramming of ESCs and iPSCs into neural stem cells and into neurons of the brain and retina [2,47,52,54,97,98,99] ENSG00000198894 PMC11640686__F2 Some small molecules and signaling pathways promoting the development of the nervous system (based on the poster https://www ENSG00000198793 ENSG00000156574 ENSG00000128602 PMC11640686__F3 Chemically induced reprogramming of fibroblasts into neural stem cells and into neurons in the brain and retina [12,36,37,39,41,42,43,85,86] ENSG00000198894 ENSG00000198670 ENSG00000164690 PMC3294063__F1A Molecular Pathways: Beta-adrenergic signaling in cancer ENSG00000102145 ENSG00000111537 ENSG00000002330 ENSG00000291971 ENSG00000019549 ENSG00000100985 ENSG00000113302 ENSG00000073756 ENSG00000168610 PMC4992436__F1 Emerging Roles for Non-canonical NFKB Signaling in the Modulation of Inflammatory Bowel Disease Pathobiology ENSG00000125538 ENSG00000082512 ENSG00000173039 ENSG00000127191 PMC4992436__F2 Emerging Roles for Non-canonical NFKB Signaling in the Modulation of Inflammatory Bowel Disease Pathobiology ENSG00000104856 ENSG00000107562 ENSG00000131323 ENSG00000127191 PMC7541492__F2 Tumor microenvironment (TME) contributes to resistance via EMT ENSG00000108691 ENSG00000101751 ENSG00000100985 ENSG00000121807 ENSG00000146648 PMC3642156__F1 Host immune response to viral infection (Interferon Signaling Pathways) ENSG00000105397 ENSG00000175104 ENSG00000184216 PMC4314327__F3 Macrophage immunoregulatory pathways in tuberculosis ENSG00000198125 PMC9652895__F7 Celastrol elicits antitumor effects by inhibiting the STAT3 pathway through ROS accumulation in non-small cell lung cancer ENSG00000128272 ENSG00000171791 ENSG00000168610 PMC8651562__F1 Suppression of InterferonA Treatment Response by Host Negative Factors in Hepatitis B Virus Infection ENSG00000184979 ENSG00000213928 ENSG00000187608 ENSG00000105397 ENSG00000115415 ENSG00000185201 ENSG00000146648 ENSG00000276561 ENSG00000142166 PMC4171984__F1 Insulin/IGF-1 signaling pathways ENSG00000002330 ENSG00000106070 ENSG00000198793 ENSG00000169047 ENSG00000164327 PMC4420735__F3 A model of telomerase RNP biogenesis ENSG00000145912 ENSG00000109534 ENSG00000291996 ENSG00000164362 PMC2943318__F7 Ulk3 function in Shh signaling pathway ENSG00000164690 ENSG00000128602 PMC3636752__F1 Distinct activation pathways for different CDKs ENSG00000135446 ENSG00000123374 ENSG00000277273 ENSG00000276876 PMC5531345__F7 Scheme of the pathway mediating the VEGF-induced disassembly of adherence junctions and its regulation by NDPK-B ENSG00000168036 PMC7948516__F1 Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing ENSG00000138604 ENSG00000042832 ENSG00000111371 PMC5742161__F11 The illustration of CGA protecting against liver fibrosis in vitro and in vivo by regulating miR-21-regulated TGFB1/Smad7 signaling pathway PMC6699068__F1 Notch signaling in bone tissue development ENSG00000148400 ENSG00000074181 ENSG00000167941 ENSG00000168036 PMC7339205__F7 PLK1 regulates hepatic stellate cell activation and liver fibrosis through Wnt/B‐catenin signalling pathway ENSG00000134982 ENSG00000168036 ENSG00000166851 PMC6923660__F8 The activation of leptin signaling pathway in preadipocytes induces adipogenesis and the production of proinflammatory cytokines ENSG00000198793 PMC5378934__F8 Schematic model of TBL1XR1-promoting ERK activation and gastric cancer progression ENSG00000169554 ENSG00000137673 ENSG00000170558 ENSG00000168036 ENSG00000177565 PMC5993186__F1 Coproheme decarboxylases - Phylogenetic prediction versus biochemical experiments ENSG00000126088 ENSG00000256269 ENSG00000188690 PMC6374012__F1 Quantitative systems pharmacology of interferon alpha administration: A multi-scale approach ENSG00000105397 ENSG00000115415 PMC4043133__F9 Proposed site of PEP7 inhibition of the AT1R-Erk1/2 signaling cascade ENSG00000138798 ENSG00000146648 PMC9109208__F5 It's about time; divergent circadian clocks in livers of mice and naked mole-rats ENSG00000138030 ENSG00000105516 ENSG00000132326 ENSG00000179094 PMC7862069__F3 Inhibitors targeting Bruton’s tyrosine kinase in cancers: drug development advances ENSG00000177455 ENSG00000095585 ENSG00000105369 ENSG00000110448 ENSG00000007312 ENSG00000186716 ENSG00000136997 ENSG00000172936 ENSG00000010671 ENSG00000121966 PMC6791698__F1 Metabolic pathways concerning dTTP biosynthesis ENSG00000228716 ENSG00000124479 ENSG00000178445 PMC6616624__F5 Main energy metabolism and carbon/nitrogen fluxes in heterocysts ENSG00000122966 ENSG00000172005 ENSG00000062485 PMC9223434__F7 Application of Sensitivity Analysis to Discover Potential Molecular Drug Targets ENSG00000213928 ENSG00000115415 ENSG00000125347 ENSG00000142166 PMC2040031__F1 INTERLINKING INTERLEUKIN-7 ENSG00000002330 ENSG00000105639 PMC8122377__F3 Hepcidin Signaling in Health and Disease: Ironing Out the Details ENSG00000170365 ENSG00000172936 ENSG00000168610 PMC4911360__F14 Gene-network of not isolated genes selected by Net-Cox in the GSE7390 breast dataset ENSG00000066468 ENSG00000145839 ENSG00000171791 ENSG00000095002 PMC7422622__F1 Targeting cellular senescence in cancer and aging: roles of p53 and its isoforms ENSG00000019991 ENSG00000003436 ENSG00000163453 ENSG00000137801 PMC4911360__F11 Gene-network of not isolated genes selected by Adalnet in the TCGA ovarian dataset ENSG00000134982 ENSG00000140829 ENSG00000137198 ENSG00000104290 ENSG00000139687 PMC2774752__F1 Puzzles, promises and a cure for ageing ENSG00000124102 ENSG00000171791 PMC4467383__F4 Inhibition of BET bromodomains as a therapeutic strategy for cancer drug discovery ENSG00000169925 ENSG00000141867 ENSG00000006712 ENSG00000137948 PMC7444709__F3 Physiological and pathophysiological functions mediated by TRPC4 in response to receptor-operated activation of Gq/11 and/or Gi/o proteins. A & B ENSG00000196531 ENSG00000133107 ENSG00000144935 ENSG00000078747 ENSG00000171540 PMC4467383__F2 Inhibition of BET bromodomains as a therapeutic strategy for cancer drug discovery ENSG00000169925 ENSG00000102145 ENSG00000141867 PMC2808158__F7 Schematic summary of effect of IL-4 priming on phagocytic and secretory capacities of MΦs ENSG00000169047 ENSG00000105639 ENSG00000175104 PMC9630328__F1 Tumor innate immune microenvironment in prostate cancer: an overview of soluble factors and cellular effectors ENSG00000049768 ENSG00000168610 PMC10555535__F1 Metabolic pathway of exogenous and endogenous lipoproteins ENSG00000130164 PMC9630328__F2 Tumor innate immune microenvironment in prostate cancer: an overview of soluble factors and cellular effectors ENSG00000167601 ENSG00000102962 ENSG00000108691 ENSG00000107562 ENSG00000111537 ENSG00000181847 ENSG00000169429 ENSG00000010278 ENSG00000231179 ENSG00000204520 ENSG00000168610 PMC9141761__F1 Biliverdin Reductase A in the Regulation of Insulin Signaling in Metabolic and Neurodegenerative Diseases: An Update ENSG00000169047 ENSG00000198793 PMC9141761__F2 Biliverdin Reductase A in the Regulation of Insulin Signaling in Metabolic and Neurodegenerative Diseases: An Update ENSG00000142192 ENSG00000169047 PMC3231999__F1 Immune evasion strategies of Porphyromonas gingivalis ENSG00000174125 ENSG00000121966 PMC7689244__F9 iTRAQ-based proteomics reveals serum protein changes in hypertensive rats induced by a high-salt diet ENSG00000169291 ENSG00000002330 ENSG00000168036 PMC5039409__F3 Cardiovascular Disease Chemogenomics Knowledgebase-guided Target Identification and Drug Synergy Mechanism Study of an Herbal Formula ENSG00000113161 ENSG00000143839 ENSG00000087085 ENSG00000198074 ENSG00000043591 ENSG00000166169 ENSG00000146648 ENSG00000196689 ENSG00000274542 ENSG00000132170 PMC8008708__F2 Scheme depicting the biogenesis of different classes of EVs ENSG00000165527 ENSG00000146648 ENSG00000111737 PMC5925008__F5 Summary of working thesis of the study ENSG00000162711 ENSG00000125538 PMC5761662__F8 Oncogenic KRAS regulates amino acid homeostasis and asparagine biosynthesis via ATF4 and alters sensitivity to L-asparaginase ENSG00000138744 ENSG00000128272 ENSG00000144895 ENSG00000101255 ENSG00000162772 ENSG00000070669 PMC8634476__F2 Placental Angiogenesis in Mammals: A Review of the Regulatory Effects of Signaling Pathways and Functional Nutrients ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC8634476__F3 Placental Angiogenesis in Mammals: A Review of the Regulatory Effects of Signaling Pathways and Functional Nutrients ENSG00000167772 ENSG00000128917 ENSG00000112715 ENSG00000125245 PMC1168814__F8 The regulation of replication-dependent histone H4 genes at the G1/S phase cell cycle transition via the cyclin E/CDK2/p220/HiNF-P pathway relative to the E2F/pRB pathway ENSG00000228716 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC8634476__F1 Placental Angiogenesis in Mammals: A Review of the Regulatory Effects of Signaling Pathways and Functional Nutrients ENSG00000002330 ENSG00000128917 ENSG00000198793 ENSG00000112715 ENSG00000150630 PMC2361340__F5 Differential targets of copy number-induced expression changes in key biochemical pathways between SCLC and NSCLC ENSG00000087095 ENSG00000050748 ENSG00000176887 ENSG00000184445 ENSG00000291561 ENSG00000196628 ENSG00000153487 ENSG00000156299 ENSG00000135446 ENSG00000189403 ENSG00000123374 ENSG00000146648 ENSG00000282899 PMC6023588__F4 Metabolic mechanisms of exercise-induced cardiac growth ENSG00000179862 ENSG00000172216 ENSG00000198793 PMC6023588__F3 Schematic of glycolysis and ancillary glucose metabolism pathways ENSG00000173599 ENSG00000026103 PMC10343257__F10 Therapeutic Effects and Molecular Mechanism of Chlorogenic Acid on Polycystic Ovarian Syndrome: Role of HIF-1alpha ENSG00000162711 ENSG00000198793 PMC11676223__F1 Irisin: A Multifaceted Hormone Bridging Exercise and Disease Pathophysiology ENSG00000162711 ENSG00000128272 ENSG00000198793 ENSG00000175567 PMC7880431__F4 Anti-epileptic drug topiramate upregulates TGFB1 and SOX9 expression in primary embryonic palatal mesenchyme cells: Implications for teratogenicity ENSG00000125398 ENSG00000105329 ENSG00000057593 ENSG00000100564 ENSG00000164690 ENSG00000151148 PMC9265893__F3 Ferroptosis and Its Role in Chronic Diseases ENSG00000170522 ENSG00000167468 ENSG00000198793 ENSG00000115107 PMC5304257__F2 miRNAs control inflammatory response in ECs ENSG00000108691 ENSG00000163739 ENSG00000127528 PMC9100407__F9 Proteomic Investigation of Molecular Mechanisms in Response to PEG-Induced Drought Stress in Soybean Roots ENSG00000073578 ENSG00000173599 ENSG00000062485 PMC9701458__F4 Integrated Network Pharmacology Analysis and Experimental Validation to Investigate the Molecular Mechanism of Triptolide in the Treatment of Membranous Nephropathy ENSG00000143839 ENSG00000170606 ENSG00000171791 ENSG00000121807 ENSG00000137845 ENSG00000126218 ENSG00000156103 ENSG00000082175 ENSG00000095303 ENSG00000136869 ENSG00000001626 ENSG00000077782 ENSG00000064012 ENSG00000087245 ENSG00000197635 ENSG00000007908 ENSG00000043591 ENSG00000007171 ENSG00000132170 ENSG00000138207 ENSG00000103769 ENSG00000146648 ENSG00000178568 ENSG00000291603 ENSG00000070831 ENSG00000291971 ENSG00000140505 ENSG00000198793 ENSG00000087085 ENSG00000113161 ENSG00000150093 ENSG00000169032 ENSG00000164305 ENSG00000010671 ENSG00000163631 ENSG00000180210 ENSG00000086205 ENSG00000149968 ENSG00000196549 ENSG00000128052 ENSG00000148346 ENSG00000171105 ENSG00000259207 ENSG00000157764 ENSG00000109320 ENSG00000198931 ENSG00000067900 ENSG00000073756 ENSG00000168610 ENSG00000066468 ENSG00000176884 ENSG00000015285 ENSG00000100985 ENSG00000115232 PMC8187928__F1 Cellular cholesterol metabolism ENSG00000110921 ENSG00000130164 ENSG00000138135 ENSG00000163914 ENSG00000113161 ENSG00000104549 ENSG00000141458 ENSG00000160179 PMC7813762__F5 Representative metabolic pathway maps of differentially expressed proteins involved in TCA cycle (A) and proteasome (B) in KEGG ENSG00000163902 ENSG00000198576 ENSG00000291973 PMC6425834__F2 Models for potential interaction between Toll-like receptor 4 (TLR4) and protease-activated receptor 2 (PAR2).(A) Direct interaction at the plasma membrane model ENSG00000183735 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 PMC10572466__F6 Schematic drawing illustrating the action mechanisms underlying the effects of baicalin on cytoskeleton rearrangement induced by PVL in BMECs ENSG00000106683 ENSG00000182541 PMC11676223__F3 Figure depicts the capacity of irisin to affect multiple pathways involved in age-associated neurodegeneration and mechanisms underlying AD pathogenesis ENSG00000160097 ENSG00000096717 PMC9610703__F5 Current Insights into miRNA and lncRNA Dysregulation in Diabetes: Signal Transduction, Clinical Trials and Biomarker Discovery ENSG00000070193 ENSG00000150907 ENSG00000169047 ENSG00000171791 ENSG00000096717 ENSG00000197063 ENSG00000079999 PMC3071979__F2 Inhibition of NFKB signaling retards eosinophilic dermatitis in SHARPIN-deficient mice ENSG00000142192 ENSG00000291603 ENSG00000090402 ENSG00000138798 ENSG00000196591 ENSG00000173039 ENSG00000150455 ENSG00000127191 ENSG00000226275 ENSG00000244687 ENSG00000148798 ENSG00000197943 ENSG00000117335 ENSG00000172936 PMC8840292__F6 Microplastics (Polystyrene) Exposure Induces Metabolic Changes in the Liver of Rare Minnow (Gobiocypris rarus) ENSG00000100422 ENSG00000197746 ENSG00000172005 ENSG00000133063 ENSG00000150967 ENSG00000117528 ENSG00000073734 ENSG00000173208 ENSG00000078237 ENSG00000124795 PMC98985__F3 Overview of metabolic pathways for glucose and xylose metabolism ENSG00000047597 ENSG00000158125 PMC6677770__F7 Scheme of SAMHD1’s role in HMA metabolism and effector functions ENSG00000158825 ENSG00000129187 PMC8918542__F1 Clinical Importance of Potential Genetic Determinants Affecting Propofol Pharmacokinetics and Pharmacodynamics ENSG00000196502 ENSG00000197408 PMC7728170__F2 Interleukin-17A pathway target genes are upregulated in Equus caballus supporting limb laminitis ENSG00000143546 ENSG00000163220 ENSG00000100985 ENSG00000115009 PMC2773646__F1 Nodal signaling pathway ENSG00000160973 ENSG00000156574 PMC4739231__F1 Signaling pathways demonstrating the link between Gq-coupled receptors and induction of autoimmunity ENSG00000198793 ENSG00000168610 PMC9359488__F2 Host genetic diversity and genetic variations of SARS-CoV-2 in COVID-19 pathogenesis and the effectiveness of vaccination ENSG00000039537 ENSG00000213928 ENSG00000113600 ENSG00000105516 ENSG00000121807 ENSG00000276561 ENSG00000111537 ENSG00000161921 ENSG00000105397 ENSG00000136869 ENSG00000172936 ENSG00000142089 ENSG00000164342 PMC9265893__F1 Ferroptosis and Its Role in Chronic Diseases ENSG00000168003 ENSG00000161905 ENSG00000128272 ENSG00000151012 ENSG00000076554 ENSG00000197635 ENSG00000196839 ENSG00000167468 ENSG00000115107 PMC3614511__F8 Transcriptional Corepressors HIPK1 and HIPK2 Control Angiogenesis Via TGFB–TAK1–Dependent Mechanism ENSG00000061273 ENSG00000166670 ENSG00000081189 PMC4516533__F5 Proposed model for EGFR-related signal transduction pathways regulating Snail in Ishikawa (A), Ishikawa ER- (B) and primary human endometrial tumours (C) ENSG00000149269 ENSG00000138798 ENSG00000146648 PMC3818893__F6 Hypothetical role of the AhR pathway in the development of inflammatory bowel disease after exposure to environmental PAH ENSG00000125538 ENSG00000171759 ENSG00000106546 PMC6199630__F12 MAPK and PI3K signaling pathways ENSG00000070831 ENSG00000065361 ENSG00000291971 ENSG00000198793 ENSG00000163914 ENSG00000169047 ENSG00000081189 ENSG00000140443 PMC2857176__F3 Map of selected p53 pathway-associated genes that harbor known or potential functional SNPs (octagon-shaped boxes) and their closely interacting genes (rectangular boxes) ENSG00000149311 ENSG00000078900 ENSG00000135446 ENSG00000136997 ENSG00000123374 ENSG00000026103 ENSG00000198625 PMC6733437__F1 Prediction of risk scores for colorectal cancer patients from the concentration of proteins involved in mitochondrial apoptotic pathway PMC2147077__F4 A High Quality Draft Consensus Sequence of the Genome of a Heterozygous Grapevine Variety ENSG00000067064 ENSG00000197429 PMC7606590__F1 Intracellular model of GH signaling under normal and pathological conditions in Human adipocytes: ENSG00000291971 ENSG00000123689 PMC8073060__F2 Cardiac cAMP-PKA Signaling Compartmentalization in Myocardial Infarction ENSG00000108599 ENSG00000074410 ENSG00000113448 PMC11562642__F5 Schematic diagram illustrating the toxicity mechanism of MNNG in the gastric mucosa and the protection mechanism of FA against MNNG-induced gastric mucosal injury ENSG00000162711 ENSG00000198793 PMC3944655__F1 Molecular mechanisms linking ROS, antioxidants, and the insulin signalling pathway ENSG00000169047 ENSG00000142082 PMC9891206__F2 Targeting STING: From antiviral immunity to treat osteoporosis ENSG00000183735 ENSG00000164430 PMC6199630__F15 Targeted and Off-Target (Bystander and Abscopal) Effects of Radiation Therapy: Redox Mechanisms and Risk/Benefit Analysis ENSG00000188486 ENSG00000149311 ENSG00000146648 PMC8560265__F5 Increased Death of Peripheral Blood Mononuclear Cells after TLR4 Inhibition in Sepsis Is Not via TNF/TNF Receptor-Mediated Apoptotic Pathway ENSG00000136869 ENSG00000171791 PMC3072659__F1 Pathways that modulate canonical Wnt signaling ENSG00000019991 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000138798 ENSG00000168036 PMC5342722__F7 Sulfatase-1downregulates mesothelin and leads to reduction in lymphatic metastasis ENSG00000002330 ENSG00000123374 ENSG00000102854 ENSG00000168610 ENSG00000125084 PMC4089392__F1 Toward the development of podocyte-specific drugs ENSG00000171992 ENSG00000010810 ENSG00000136869 ENSG00000137672 PMC6620681__F1 De novo and salvage pathways for NAD+ biosynthesis ENSG00000105835 ENSG00000278488 PMC6200785__F8 Indian hedgehog homolog signaling pathway ENSG00000162552 ENSG00000164736 ENSG00000082175 ENSG00000117425 ENSG00000164107 ENSG00000073111 ENSG00000076003 ENSG00000163501 ENSG00000136826 PMC8111986__F5A Identification of an immune classification for cervical cancer and integrative analysis of multiomics data ENSG00000143549 ENSG00000019186 ENSG00000111837 PMC3193487__F1 Schematic of crosstalk between TLR pathway and MHC molecules ENSG00000172936 ENSG00000136869 ENSG00000010671 ENSG00000164342 PMC6119347__F2 Network created by Ingenuity Pathway Analysis using the top 36 most highly connected genes disrupted by rolandic epilepsy (RE) CNVs as assessed by the Disease Association Protein-Protein Link Evaluator ENSG00000104365 ENSG00000054179 ENSG00000197177 ENSG00000027644 ENSG00000149571 ENSG00000134007 ENSG00000187961 ENSG00000161642 ENSG00000146243 ENSG00000076555 ENSG00000142082 ENSG00000144045 ENSG00000169752 ENSG00000164488 ENSG00000275331 ENSG00000115415 ENSG00000150672 ENSG00000177606 ENSG00000140511 ENSG00000163638 ENSG00000277401 ENSG00000178568 PMC9208181__F1 Central nervous system effects of 5-HT7 receptors: a potential target for neurodegenerative diseases ENSG00000070831 ENSG00000198793 ENSG00000163914 PMC3255978__F7 Proposed mechanisms underlying the regulatory control of fibrosis development by the PAI-1/uPA balance in aged-associated muscle dystrophy progression ENSG00000122194 PMC11653397__F5 Proposed metabolic pathway of PCB95 in mice exposed to PCB95 based on the LC–HRMS analysis of intestinal content samples ENSG00000147162 ENSG00000104808 PMC7066079__F7 Proposed model to illustrate the role of FAM83A in the Wnt and Hippo signaling pathways ENSG00000134982 ENSG00000168036 ENSG00000147689 PMC6895193__F6 As a tumor-suppressor gene, RASSF1A mainly acts as a crossroad of three intertwined molecular signaling mechanisms including Ras/Rho GTPases, MTs, and Hippo pathway ENSG00000094631 ENSG00000278268 ENSG00000198793 ENSG00000163914 ENSG00000130479 PMC8980946__F1 JAK‐STAT core cancer pathway: An integrative cancer interactome analysis ENSG00000019991 ENSG00000033327 ENSG00000099985 ENSG00000242689 ENSG00000138798 ENSG00000198793 ENSG00000145777 ENSG00000168610 ENSG00000139618 ENSG00000012048 ENSG00000198901 ENSG00000138378 ENSG00000138336 ENSG00000183337 ENSG00000115415 ENSG00000173757 ENSG00000128342 ENSG00000105810 ENSG00000026103 PMC3558831__F6 PIAs recapitulate the activity of two tumor suppressors that converge on mTOR ENSG00000198793 PMC1856802__F5 Canonical Wnt signalling pathway and its APC partner in colon cancer development ENSG00000010810 ENSG00000168036 PMC5198184__F1 Metabolic stress-mediated induction of an inflammatory response via ER stress signaling pathways ENSG00000108691 ENSG00000144895 ENSG00000125538 ENSG00000100219 PMC1856802__F2 Canonical Wnt signalling pathway and its APC partner in colon cancer development ENSG00000134982 ENSG00000168036 PMC3062534__F1 Mutations in Complement Regulatory Proteins Predispose to Preeclampsia: A Genetic Analysis of the PROMISSE Cohort ENSG00000000971 PMC8712397__F5 Tools, Tactics, and Objectives to Interrogate Cellular Roles of O-GlcNAc in Disease ENSG00000147162 ENSG00000130726 PMC8712397__F1 Tools, Tactics, and Objectives to Interrogate Cellular Roles of O-GlcNAc in Disease ENSG00000147162 ENSG00000198408 ENSG00000154059 PMC9369364__F3 TM4SF5-Mediated Regulation of Hepatocyte Transporters during Metabolic Liver Diseases ENSG00000108691 ENSG00000174059 ENSG00000081051 ENSG00000096717 ENSG00000142484 PMC10705753__F1 Illustration of semaphorin 6A–D signaling pathways and their interaction with the cellular molecular network in cancer cells ENSG00000122882 ENSG00000169554 ENSG00000148400 ENSG00000291971 ENSG00000019549 ENSG00000168036 ENSG00000167680 ENSG00000137872 ENSG00000114315 ENSG00000077782 ENSG00000168610 ENSG00000196628 PMC7880431__F1 Anti-epileptic drug topiramate upregulates TGFB1 and SOX9 expression in primary embryonic palatal mesenchyme cells: Implications for teratogenicity ENSG00000121989 ENSG00000228716 ENSG00000281324 ENSG00000092445 ENSG00000142798 ENSG00000133937 ENSG00000163132 ENSG00000126261 ENSG00000183765 ENSG00000113558 ENSG00000116030 ENSG00000077782 ENSG00000182580 ENSG00000276799 ENSG00000135414 ENSG00000213341 ENSG00000139219 ENSG00000138604 ENSG00000180447 ENSG00000124216 ENSG00000131668 ENSG00000164093 ENSG00000146648 ENSG00000070814 ENSG00000105329 ENSG00000102871 ENSG00000172893 ENSG00000135341 ENSG00000122194 ENSG00000106546 ENSG00000108963 ENSG00000070444 ENSG00000176692 ENSG00000129757 ENSG00000196344 ENSG00000139579 ENSG00000168505 ENSG00000088305 ENSG00000090776 ENSG00000184916 ENSG00000164920 ENSG00000133216 ENSG00000173714 ENSG00000066468 ENSG00000052850 ENSG00000001630 ENSG00000057593 ENSG00000019549 ENSG00000134853 ENSG00000164690 ENSG00000198625 PMC10705753__F3 Illustration of the mTOR–Sema6D–PPARG signaling pathway in controlling macrophage polarization toward anti-inflammatory (antitumorigenic) phenotype M2 via regulation of fatty acid uptake and metabolic reprogramming ENSG00000135218 ENSG00000137872 ENSG00000118520 ENSG00000132170 PMC5496883__F3 Signalling by Rho GTPases (upper panel) and Neuronal system pathway (bottom panel) ENSG00000069431 ENSG00000070831 ENSG00000185760 ENSG00000157542 PMC9688694__F1 Antitumor Activities of Interleukin-12 in Melanoma ENSG00000134460 ENSG00000096996 ENSG00000138378 ENSG00000115415 ENSG00000137265 ENSG00000125347 ENSG00000168610 PMC7288986__F1 HDR-mediated genome editing ENSG00000147168 ENSG00000158517 PMC5338640__F3 Modeling, Signaling and Integrated Modeling-experimental Frameworks in Cell Migration ENSG00000070831 ENSG00000291971 PMC12209467__F3 HIF signaling pathway and targeted therapy in PH ENSG00000081181 ENSG00000105835 ENSG00000002330 ENSG00000137033 ENSG00000109321 ENSG00000112715 ENSG00000168610 ENSG00000121966 ENSG00000068028 ENSG00000215021 ENSG00000261371 ENSG00000108691 ENSG00000124216 ENSG00000160208 ENSG00000112242 ENSG00000122691 ENSG00000132646 ENSG00000019549 ENSG00000159399 PMC6333681__F1 Environmental pollutant-induced obesity and metabolic diseases: involvement of BAT impairment ENSG00000142611 ENSG00000132170 PMC5338640__F4 Modeling, Signaling and Integrated Modeling-experimental Frameworks in Cell Migration ENSG00000154342 ENSG00000134982 ENSG00000167701 PMC8170118__F3 Genome-scale mechanistic modeling of signaling pathways made easy: A bioconductor/cytoscape/web server framework for the analysis of omic data ENSG00000142192 ENSG00000130402 ENSG00000137076 ENSG00000171791 PMC12209467__F4 MAPK and PI3K/Akt signaling pathways in PH ENSG00000170365 ENSG00000132646 ENSG00000198793 ENSG00000171759 ENSG00000204217 ENSG00000165819 PMC8170118__F5 Genome-scale mechanistic modeling of signaling pathways made easy: A bioconductor/cytoscape/web server framework for the analysis of omic data ENSG00000068028 ENSG00000213658 ENSG00000243708 PMC12209467__F2 BMPR2 and TGFB signaling pathways in PH ENSG00000189283 ENSG00000105664 ENSG00000186088 ENSG00000067057 ENSG00000148400 ENSG00000132646 ENSG00000158747 ENSG00000168610 ENSG00000169375 ENSG00000204217 ENSG00000125968 PMC4486076__F1 Autophagy in Autoimmune Disease ENSG00000177169 ENSG00000152348 ENSG00000110497 ENSG00000123395 ENSG00000083290 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 ENSG00000062716 PMC12209467__F7 Wnt signaling pathway and targeted therapy in PH ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000070831 ENSG00000122691 ENSG00000132646 ENSG00000122877 ENSG00000168036 ENSG00000155760 ENSG00000196628 PMC12209467__F8 BMPR2 and TGFB crosstalk with other signaling pathways in PH ENSG00000170365 ENSG00000115415 ENSG00000291971 ENSG00000074181 ENSG00000168036 ENSG00000189403 ENSG00000169429 ENSG00000136869 ENSG00000177283 ENSG00000155760 ENSG00000204217 PMC12209467__F5 NFKB and NLRP3 signaling pathways in PH ENSG00000137807 ENSG00000162711 ENSG00000100429 ENSG00000036828 PMC12209467__F6 Notch and AMPK signaling pathways in PH ENSG00000145604 ENSG00000128917 ENSG00000148400 ENSG00000291971 ENSG00000074181 ENSG00000198793 ENSG00000086991 ENSG00000171759 ENSG00000253352 ENSG00000114315 ENSG00000096717 ENSG00000204217 PMC9812393__F8 SKN-1A/Nrf1 lipid homeostasis response ENSG00000166819 ENSG00000197296 ENSG00000173599 PMC12209467__F9 PI3K, NFKB and AMPK crosstalk with other signaling pathways in PH ENSG00000162711 ENSG00000128917 ENSG00000171759 ENSG00000175104 PMC11759460__F7 Graphical abstract ENSG00000005893 ENSG00000112561 ENSG00000177084 PMC5286959__F1 SCFFBW7 ubiquitin ligase targets SOX9 for proteasomal destruction ENSG00000125398 ENSG00000198793 ENSG00000146648 PMC6566201__F6 Fighting Thyroid Cancer with Microgravity Research ENSG00000148346 ENSG00000087245 ENSG00000214078 ENSG00000138798 ENSG00000173039 ENSG00000163064 ENSG00000165527 ENSG00000112715 ENSG00000108518 ENSG00000089159 ENSG00000108691 ENSG00000118785 ENSG00000164136 ENSG00000169429 ENSG00000112115 ENSG00000162692 ENSG00000102974 PMC8996529__F6 Jasmonates and Histone deacetylase 6 activate Arabidopsis genome-wide histone acetylation and methylation during the early acute stress response ENSG00000095321 ENSG00000084774 PMC8422639__F11 Synergy of nanodiamond–doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells ENSG00000165733 ENSG00000189403 PMC9063253__F4 V-ATPase in cell death and cancer ENSG00000138449 ENSG00000139644 ENSG00000153094 ENSG00000167468 ENSG00000198793 ENSG00000112561 ENSG00000168610 ENSG00000064012 ENSG00000164305 PMC5539153__F8 Representative model of some signaling pathways in a human breast cancer cell (MDA-MB-231) that can be modulated by GCdcPLI ENSG00000002330 ENSG00000198793 ENSG00000171791 PMC9620650__F2 Role of autophagy induced by FLT3-ITD and acid ceramidase in acute myeloid leukemia chemo-resistance: new insights ENSG00000177169 ENSG00000123395 ENSG00000128272 ENSG00000147869 ENSG00000198793 ENSG00000096717 ENSG00000057663 ENSG00000121966 PMC128926__F2 Activation of the NFKB pathway by IL-1 ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000115594 PMC6789187__F2 Citrate produced through mitochondrial metabolism can enter the fatty acid synthesis pathway ENSG00000131473 ENSG00000113161 ENSG00000198670 ENSG00000166278 ENSG00000099194 ENSG00000026103 PMC3398118__F1 Diagram of the pentose phosphate pathway showing substrates and enzymes involved in it ENSG00000171174 ENSG00000197713 ENSG00000153574 PMC5538844__F10 Cell mechanisms by which MPLA prevents inhibition of absorption by LPS in the MTAL ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC6521490__F3 By KEGG pathway enrichment analysis, ANXA2 upregulated filopodia pathway, resulting in cell metastasis ENSG00000175054 ENSG00000169291 ENSG00000010810 ENSG00000163914 ENSG00000089159 PMC3713495__F4 EZH2 promotes E2F driven SCLC tumorigenesis through modulation of apoptosis and cell cycle regulation ENSG00000228716 ENSG00000002330 ENSG00000112242 ENSG00000132646 ENSG00000139687 ENSG00000282899 PMC7767241__F1 Diagram highlighting prominent pre- and post-transcriptional interactions between NFKB and the Lin28/let-7 pathways ENSG00000104856 ENSG00000131914 ENSG00000136997 ENSG00000173039 ENSG00000187772 ENSG00000168610 PMC7786975__F1 Metabolic characteristics of M1/M [LPS(±IFNG)] macrophages ENSG00000180210 ENSG00000131473 ENSG00000100412 PMC7786975__F2 Metabolic characteristics of M2/M [IL-4/IL-10] macrophages ENSG00000180210 ENSG00000135218 ENSG00000118520 ENSG00000115419 PMC7601745__F4A Indoxyl Sulfate-Mediated Metabolic Alteration of Transcriptome Signatures in Monocytes of Patients with End-Stage Renal Disease (ESRD) ENSG00000011198 ENSG00000170677 ENSG00000099377 ENSG00000176871 ENSG00000288499 ENSG00000285395 ENSG00000111684 ENSG00000169429 ENSG00000155659 ENSG00000076716 ENSG00000198734 ENSG00000121060 ENSG00000127948 PMC3777336__F4 Differentially expressed genes (DEGs) related to the cell cycle ENSG00000118007 ENSG00000108055 ENSG00000134982 ENSG00000205250 ENSG00000091651 ENSG00000277273 ENSG00000101224 ENSG00000117399 ENSG00000274473 ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000101972 ENSG00000112242 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000282899 PMC7862680__F7 Novel ZEB1-upregulated protein PRTG induced by Helicobacter pylori infection promotes gastric carcinogenesis through the cGMP/PKG signaling pathway ENSG00000166450 PMC7330686__F3 Aromatic hydrocarbon in conjunction with CYP1B1 signalling pathway ENSG00000171759 ENSG00000106546 PMC8717598__F1 Toxoplasma gondii apicoplast-resident ferredoxin is an essential electron transfer protein for the MEP isoprenoid-biosynthetic pathway ENSG00000182511 ENSG00000197429 ENSG00000026103 PMC4436905__F1 Adipocyte secreted leptin and interleukin-6 has a paracrine effect on nearby breast cancer cells ENSG00000168610 PMC12016271__F10 SFI on podocyte INSR and eNOS proteins in the IR signaling pathway ENSG00000171105 ENSG00000169047 PMC7695578__F7 Schematic model showing the hypothesis for COVID-19 infection ENSG00000105397 ENSG00000115415 ENSG00000130234 PMC4601492__F5 Coronin-1C-mediated Rac1 trafficking ENSG00000110880 PMC6181017__F9 Suggested Schemes for PGI1-Mediated Biosynthesis of MEP Pathway Isoprenoid-Derived CKs and GAs in Cells of Vascular Tissues, and FAs and Proteins in Mixotrophic Maturing Embryos of Arabidopsis ENSG00000197429 ENSG00000167701 PMC4462002__F7 Fanconi Anemia Pathway ENSG00000175054 ENSG00000105486 ENSG00000107949 ENSG00000188827 ENSG00000162607 PMC9277157__F8 Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Carrying MicroRNA-29a Improves Ovarian Function of Mice with Primary Ovarian Insufficiency by Targeting HMG-Box Transcription Factor/Wnt/Beta-Catenin Signaling ENSG00000134982 ENSG00000168036 PMC11768371__F7 Mechanism underlying the gedunin-mediated inhibition of C ENSG00000162711 ENSG00000172936 PMC8943601__F1 Glucagon-Like Peptide-1 Receptor Agonists (GLP-1 RA) in Diabetes-Related Neurodegenerative Diseases ENSG00000002330 ENSG00000169047 ENSG00000198793 PMC3021862__F4 Genes regulated by Survivin in ITD-Flt3+KSL cells and deregulated in LSC are mapped on functional signaling network associated with epidermal growth factor receptor signaling pathway ENSG00000109163 ENSG00000157557 ENSG00000070831 ENSG00000110799 ENSG00000291971 ENSG00000134278 ENSG00000164136 ENSG00000146648 ENSG00000095794 PMC4955670__F4 Global Gene Profiling of Spontaneous Hepatocellular Carcinoma in B6C3F1 Mice: Similarities in the Molecular Landscape with Human Liver Cancer ENSG00000112576 ENSG00000148346 ENSG00000109320 ENSG00000153094 ENSG00000087586 ENSG00000171791 ENSG00000081051 ENSG00000196628 ENSG00000179295 ENSG00000012048 ENSG00000160180 ENSG00000067606 ENSG00000177606 ENSG00000136997 ENSG00000146678 ENSG00000116584 ENSG00000127324 ENSG00000126458 ENSG00000282899 PMC4955670__F5 Global Gene Profiling of Spontaneous Hepatocellular Carcinoma in B6C3F1 Mice: Similarities in the Molecular Landscape with Human Liver Cancer ENSG00000104856 ENSG00000154342 ENSG00000142192 ENSG00000132824 ENSG00000168036 ENSG00000081051 ENSG00000064300 ENSG00000168283 ENSG00000157557 ENSG00000180447 ENSG00000160404 ENSG00000177606 ENSG00000005893 ENSG00000133169 ENSG00000136997 ENSG00000198517 PMC3554623__F2 Battle between Rotavirus and Its Host for Control of the Interferon Signaling Pathway ENSG00000183735 ENSG00000144895 ENSG00000276561 ENSG00000164342 PMC4955670__F6 Global Gene Profiling of Spontaneous Hepatocellular Carcinoma in B6C3F1 Mice: Similarities in the Molecular Landscape with Human Liver Cancer ENSG00000109320 ENSG00000164109 ENSG00000168036 ENSG00000087586 ENSG00000145386 ENSG00000076003 ENSG00000166851 ENSG00000179295 ENSG00000177426 ENSG00000094804 ENSG00000134057 ENSG00000160180 ENSG00000163235 ENSG00000135446 ENSG00000146678 ENSG00000127324 ENSG00000105810 PMC7859922__F1 Chemokines in hepatocellular carcinoma ENSG00000107562 ENSG00000121966 PMC4031539__F5 Summary figure of the switch from Pu.1 interaction with coactivators to corepressors caused by Runx1 deficiency ENSG00000143799 ENSG00000073584 ENSG00000163939 ENSG00000196591 ENSG00000142453 ENSG00000065717 ENSG00000292096 ENSG00000168283 ENSG00000101945 ENSG00000171720 ENSG00000159216 ENSG00000102038 ENSG00000143815 ENSG00000004487 ENSG00000139613 ENSG00000162521 ENSG00000162664 ENSG00000136518 ENSG00000134046 ENSG00000169375 ENSG00000101189 ENSG00000084093 ENSG00000071655 ENSG00000182568 ENSG00000126457 ENSG00000150459 ENSG00000106829 ENSG00000164105 ENSG00000215021 ENSG00000198901 ENSG00000108604 ENSG00000198604 ENSG00000178028 ENSG00000120616 ENSG00000124160 ENSG00000096717 ENSG00000288325 ENSG00000127616 ENSG00000130726 ENSG00000175792 ENSG00000111642 PMC5423041__F1 Molecular mechanisms involved in macrophage inflammatory protein-2 secretion of macrophages ENSG00000136869 ENSG00000168610 PMC10534417__F1 Putative biosynthesis pathway of limonin ENSG00000110921 ENSG00000197429 ENSG00000113161 ENSG00000167508 PMC3117645__F9 The miR-29 regulatory network in Zmpste24−/− progeroid mice ENSG00000070831 ENSG00000216490 ENSG00000141562 ENSG00000158050 PMC3993568__F10 PI3K/Akt1 pathway is a downstream effector of Jak2/Stat5 signaling in luminal mammary epithelial cells ENSG00000291971 ENSG00000113494 PMC506992__F7 MUC20 suppression ENSG00000277753 ENSG00000019991 PMC8708687__F2 Targeting Mitochondrial OXPHOS and Their Regulatory Signals in Prostate Cancers ENSG00000117020 ENSG00000198793 ENSG00000136997 ENSG00000197905 PMC9077852__F9 Kinesin family member 23, regulated by FOXM1, promotes triple negative breast cancer progression via activating Wnt/Beta-catenin pathway ENSG00000137807 ENSG00000168036 ENSG00000196363 PMC3116035__F3 A) Schematic outline of mitochondrial and metabolic pathways connected to the PPP in hepatocytes ENSG00000198793 ENSG00000168036 ENSG00000081051 ENSG00000196628 ENSG00000026103 ENSG00000167419 PMC3199966__F1 Schematic biosynthetic pathways for the major phospholipid (Kennedy Pathway) and sphingolipid classes biosynthesized in mammalian cells and observed in MALDI IMS of mammalian tissues ENSG00000173599 ENSG00000184207 ENSG00000102172 ENSG00000133027 PMC6680887__F3 Dinoflagellate orthologues predicted in the base excision repair pathway ENSG00000105486 ENSG00000139372 ENSG00000129071 PMC7575756__F8 Molecular mechanism underlying the tumor-suppressive effect of miR-766-3p in OS ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000186174 PMC3760013__F5 Core genes for cetuximab and PX‐866 susceptibility ENSG00000168214 ENSG00000198793 ENSG00000136997 ENSG00000146648 PMC6680887__F4 Diagrammatic summary of the dinoflagellate orthologues predicted in the nucleotide excision repair pathway ENSG00000012061 ENSG00000292191 ENSG00000134574 ENSG00000132646 ENSG00000177084 ENSG00000136936 ENSG00000122008 PMC7338796__F2 Crosstalk between the tetrahydrobiopterin (BH4) and kynurenine (KYN) pathways ENSG00000228716 ENSG00000116096 PMC9617731__F9 Helicobacter pylori Infection Elicits Type I Interferon Response in Human Monocytes via Toll-Like Receptor 8 Signaling ENSG00000187554 ENSG00000276561 PMC6680887__F5 Dinoflagellate orthologues predicted in the DNA mismatch repair pathway ENSG00000105486 ENSG00000113318 ENSG00000132646 ENSG00000095002 ENSG00000064933 PMC2952389__F1 Outline of T-cell development pathway from bone marrow to the thymus ENSG00000117091 ENSG00000020633 ENSG00000026508 PMC3390208__F8 Signaling pathway involving CaMKK regulation of GluA1 synthesis and synaptic incorporation as CP-AMPARs ENSG00000198793 PMC6518732__F1 STAT3 signaling pathway in cancer cells ENSG00000196090 ENSG00000291971 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC8430839__F2 Evasion of Antiviral Innate Immunity by Porcine Reproductive and Respiratory Syndrome Virus ENSG00000213928 ENSG00000105397 PMC7751845__F8 Crosstalk between HepG2 cells and TAMs-like macrophages PMC4049898__F2 Wnt and planar cell polarity signaling in cystic renal disease ENSG00000134982 ENSG00000112655 ENSG00000168036 PMC2883790__F2 IGF-I activation of a signaling pathway to mTOR ENSG00000124102 ENSG00000198793 ENSG00000163914 PMC6152528__F11 Hypothetical model for the signaling pathway and the role of FKB-induced autophagy in GBM cells ENSG00000128272 ENSG00000101255 ENSG00000198793 ENSG00000108443 ENSG00000057663 PMC6273124__F1 PI3K-Akt-mTOR pathway PMC4373479__F1 TLR4 signalling ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC6510893__F5 The Conserved Response of chickens to NDV infection ENSG00000115415 ENSG00000157601 ENSG00000125347 ENSG00000276561 PMC8698417__F4 Bioactive Compounds in Oxidative Stress-Mediated Diseases: Targeting the NRF2/ARE Signaling Pathway and Epigenetic Regulation ENSG00000065833 ENSG00000178573 ENSG00000079999 PMC8698417__F1 Bioactive Compounds in Oxidative Stress-Mediated Diseases: Targeting the NRF2/ARE Signaling Pathway and Epigenetic Regulation ENSG00000100387 ENSG00000079999 PMC11053566__F10 Proposed mechanisms of action of eudesmane-type sesquiterpene lactones on the TNF-Alpha-induced NFKB signaling pathway ENSG00000137275 ENSG00000102871 ENSG00000173039 ENSG00000127191 PMC7405862__F1 Mechanisms involved in organ damages associated with COVID-19 ENSG00000130234 ENSG00000125538 PMC10518439__F2 Pyroptosis and inflammasomes in cancer and inflammation ENSG00000278718 ENSG00000145649 ENSG00000189403 ENSG00000147697 ENSG00000073605 PMC5201094__F7 Hypothetic model illustrating the pivotal role of CD37 status for R-CHOP outcome in DLBCL and the important molecular mechanisms for R-CHOP resistance in CD37−DLBCL and CD37+ABC-DLBCL ENSG00000101751 ENSG00000186716 ENSG00000160223 ENSG00000136997 ENSG00000104894 ENSG00000137265 ENSG00000154059 ENSG00000168610 ENSG00000010671 ENSG00000121966 PMC6854988__F11 The GO interaction network of coexpression genes (the cnetplot of coexpression genes from BP enriched pathway) ENSG00000023839 ENSG00000106546 PMC6854988__F12 The GO interaction network of coexpression genes (the cnetplot of coexpression genes from MF enriched pathway) ENSG00000106546 PMC4229533__F1 Pancreatic cancer cell survival pathways in 5-fluorouracil resistance ENSG00000002330 ENSG00000070831 ENSG00000291971 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000168610 PMC6530474__F10 Diagrammatic representation of constitutively activated TGF-Beta-signaling-mediated tissue fibrosis ENSG00000122691 ENSG00000019549 PMC4782570__F7 Proposed regulatory mechanism of insulin expression by the Wnt/Beta-catenin/NeuroD1 pathway in the hypothalamus ENSG00000154342 ENSG00000168036 PMC6995390__F2 Signal transduction pathways in PSCs activation ENSG00000105550 ENSG00000163914 ENSG00000164690 ENSG00000163501 PMC8579446__F3 Close interactions between lncRNAs, lipid metabolism and ferroptosis in cancer ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000115107 PMC3073278__F1 Tumor-induced DSB formation in vivo ENSG00000188486 ENSG00000108691 ENSG00000138385 PMC7851696__F1 Critical Role of MetR/MetB/MetC/MetX in Cysteine and Methionine Metabolism, Fungal Development, and Virulence of Alternaria alternata ENSG00000211445 ENSG00000110395 ENSG00000132840 PMC4959648__F1 Mitochondrial Oxidative Phosphorylation System (OXPHOS) Deficits in Schizophrenia ENSG00000178127 PMC9539685__F1 Research progress on the relationship between the TOR signaling pathway regulator, epigenetics, and tumor development ENSG00000132906 ENSG00000136997 ENSG00000196792 ENSG00000115808 ENSG00000164305 ENSG00000143155 PMC9539685__F2 Research progress on the relationship between the TOR signaling pathway regulator, epigenetics, and tumor development ENSG00000143155 PMC10539319__F1 Systemic iron sources and metabolism ENSG00000089472 PMC10539319__F3 Testicular iron metabolism and ferroptosis ENSG00000151012 ENSG00000181019 ENSG00000167468 ENSG00000111684 PMC2732416__F5 Roles of the ILS pathway and HSF1 in aggregation toxicity and longevity ENSG00000124102 ENSG00000284774 PMC8000993__F7 Simplified schematic of crosstalk between JA and ABA signaling pathways ENSG00000164151 ENSG00000108798 ENSG00000163788 PMC4905215__F1 Endothelial-specific loss of GRK2 impairs maturation and vascular remodeling in adult and developmental angiogenesis ENSG00000170365 ENSG00000105329 PMC7844244__F8 CD4 derived double negative T cells prevent the development and progression of nonalcoholic steatohepatitis ENSG00000049768 PMC2862795__F1 Multi-component nature of TGFB and Wnt Pathways ENSG00000168036 PMC5498621__F6 Examples of subnetworks in network reconstructed from injured swine brain treated with VPA ENSG00000186487 ENSG00000185818 ENSG00000157404 ENSG00000147488 ENSG00000105613 ENSG00000167889 ENSG00000117707 ENSG00000100146 ENSG00000164305 ENSG00000121966 ENSG00000137801 ENSG00000140379 ENSG00000038427 ENSG00000148798 ENSG00000041515 ENSG00000291761 ENSG00000100219 ENSG00000136535 ENSG00000113492 ENSG00000100285 ENSG00000146469 ENSG00000189056 ENSG00000281931 ENSG00000102003 ENSG00000081189 ENSG00000139352 ENSG00000108691 ENSG00000277586 ENSG00000121351 ENSG00000116132 ENSG00000140285 ENSG00000146122 ENSG00000096717 ENSG00000197430 ENSG00000168490 PMC6733901__F2 Pyroptosis in cancer: pro-cancer or pro-“host”? ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000091592 ENSG00000091106 ENSG00000168040 ENSG00000276068 PMC6353984__F5 Downregulation of G2/mitotic-specific cyclinB1 triggers autophagy via AMPK-ULK1-dependent signal pathway in nasopharyngeal carcinoma cells ENSG00000177169 ENSG00000126775 ENSG00000134057 PMC7197765__F1 Cross-coupling reactions of benzylic C–H bonds and alcohols via a radical relay pathway ENSG00000004848 PMC9120423__F1 Current Landscape of mRNA Vaccines Against Viruses and Cancer–A Mini Review PMC7393494__F7 Inhibition of miR-1193 leads to synthetic lethality in glioblastoma multiforme cells deficient of DNA-PKcs ENSG00000100811 ENSG00000175054 PMC11847233__F1 Regulatory effect of lncRNA Erdr1 on T cells ENSG00000115009 ENSG00000112486 PMC3343703__F1 Heme metabolism ENSG00000144410 ENSG00000066926 ENSG00000126088 ENSG00000188690 ENSG00000198125 PMC7564904__F1 In vitro Bacillus Calmette-Guérin (BCG) training ENSG00000167207 ENSG00000125538 ENSG00000198793 PMC8364703__F5 Bacterioferritin: a key iron storage modulator that affects strain growth and butenyl-spinosyn biosynthesis in Saccharopolyspora pogona ENSG00000117118 ENSG00000161533 ENSG00000153574 ENSG00000168040 PMC7163250__F9 Our hypothetical model integrating AMP-activated protein kinase (AMPK), Hippo, and TBK1 signaling pathways during normal (A) and ZIKV-infected states (B) ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000150457 ENSG00000131023 PMC3732459__F3 Innate Immune Responses in Hepatitis C Virus Infection ENSG00000184979 ENSG00000105397 ENSG00000126457 ENSG00000142166 PMC6433789__F3 P53-HSF1-PGC1A integrated responses in HD ENSG00000284774 ENSG00000100867 ENSG00000130699 ENSG00000197386 ENSG00000109670 PMC4225745__F1 Interaction between human GD T cell and tumor cell ENSG00000169245 ENSG00000111537 ENSG00000197429 ENSG00000231179 ENSG00000204520 PMC6868871__F6 Summary diagram demonstrating the contribution of IGF-1/IGFBP to transcriptional levels of PPARG, VEGF, and HIF-1A under the administration of BV intervention ENSG00000146678 PMC3732459__F2 Innate Immune Responses in Hepatitis C Virus Infection ENSG00000183735 ENSG00000088888 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000121060 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC3234494__F3 Cytosolic RNA sensors ENSG00000167207 ENSG00000276561 PMC8868556__F5 Melatonin as a Smart Protector of Pregnancy in Dairy Cows ENSG00000172167 ENSG00000105327 ENSG00000128342 PMC4911365__F3 Tumor-supportive effects of BMAT ENSG00000164136 ENSG00000168610 PMC5454774__F1 Scar-mediated inhibition and CSPG receptors in the CNS ENSG00000198793 ENSG00000168610 PMC8024996__F1 Struggle of a good friend getting old: cellular senescence in viral responses and therapy ENSG00000164430 ENSG00000105612 ENSG00000129514 ENSG00000142082 PMC4417442__F2 HIV cell-to-cell transmission: effects on pathogenesis and antiretroviral therapy ENSG00000188486 ENSG00000162711 ENSG00000111605 ENSG00000164430 ENSG00000183486 ENSG00000163565 ENSG00000239713 PMC10981756__F7 Mechanism of the antineoplastic role of PQR309 and gemcitabine in nasopharyngeal carcinoma ENSG00000170558 ENSG00000168036 ENSG00000168610 PMC9477421__F5 Schematic diagram summarising the inferred functions of cofilin 1 (CFL1) and fatty acid binding protein 5 (FABP5) that interact with a prokaryotically-expressed (non-glycosylated) recombinant form of the Toxocara canis mucin 1 protein (rTc-MUC-1) ENSG00000102879 ENSG00000065833 ENSG00000150991 ENSG00000285246 ENSG00000108518 ENSG00000291420 ENSG00000136167 PMC2631405__F1 Role of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models ENSG00000150907 PMC5147738__F5 Portion of the miRNA-augmented Regulation of lipolysis in adipocytes pathway ENSG00000117020 ENSG00000171105 ENSG00000011198 ENSG00000121879 ENSG00000079435 ENSG00000177666 PMC2912609__F2 Currently available therapies targeting EGFR signaling pathway ENSG00000157764 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC5047222__F1 Formal modeling and analysis of the hexosamine biosynthetic pathway: role of O-linked N-acetylglucosamine transferase in oncogenesis and cancer progression ENSG00000177455 ENSG00000033327 ENSG00000147162 ENSG00000198408 ENSG00000169047 ENSG00000102104 PMC5295433__F8 G-protein-coupled receptors mediate omega-3 PUFAs-inhibited colorectal cancer by activating the Hippo pathway ENSG00000110330 ENSG00000109321 ENSG00000131023 ENSG00000276068 PMC3574586__F2 Schematic representation of the sessile and traditional serrated pathways ENSG00000157764 ENSG00000170430 ENSG00000163453 PMC6637598__F2 Wnt/Beta-catenin signal transduction pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8089042__F8 Model and Summary: RGS10 regulates pro-inflammatory gene expression through functional interaction with the SOCE machinery ENSG00000042832 ENSG00000167323 ENSG00000109689 PMC8961181__F1 Genetics, Breeding and Genetic Engineering to Improve Cottonseed Oil and Protein: A Review ENSG00000173599 ENSG00000198670 ENSG00000026103 PMC8526999__F3 Cell Cycle Entry Control in Naïve and Memory CD8+ T Cells ENSG00000179091 ENSG00000134982 ENSG00000135446 ENSG00000135913 ENSG00000123374 ENSG00000105810 PMC5449515__F2 Mechanisms governing TGFB1–induced HASM contraction PMC2726710__F2 Intracellular signaling consequences of calpain-mediated substrate cleavage ENSG00000002330 ENSG00000197971 ENSG00000168036 ENSG00000291761 PMC11850813__F7 Molecular mechanism underlying knee arthrofibrosis ENSG00000041982 ENSG00000197635 ENSG00000146648 PMC11186353__F3 Illustration representing the sites of action of different polyphenols in asthma pathway ENSG00000137033 ENSG00000145777 ENSG00000166090 PMC11186353__F4 Illustration representing the sites of action of different polyphenols in cancer pathway ENSG00000051180 ENSG00000122194 PMC3735707__F6 Maternal factors required for oocyte developmental competence in mice ENSG00000186281 PMC4641965__F1 Perspective of Small-Molecule AdipoR Agonist for Type 2 Diabetes and Short Life in Obesity ENSG00000159346 ENSG00000285070 ENSG00000175567 PMC9523578__F3 Bacterial effectors mimicking ubiquitin-proteasome pathway tweak plant immunity ENSG00000100422 ENSG00000113558 PMC8972237__F7 Phenotypical, functional and transcriptomic comparison of two modified methods of hepatocyte differentiation from human induced pluripotent stem cells ENSG00000087095 ENSG00000095739 ENSG00000134982 ENSG00000167941 ENSG00000173156 ENSG00000113558 ENSG00000198576 ENSG00000196470 ENSG00000185269 ENSG00000127948 ENSG00000262243 PMC11898993__F8 Molecular mechanism of GNC against IR-induced DOR ENSG00000127948 ENSG00000171345 PMC9179265__F1 EPA Modulates KLK Genes via miR-378: A Potential Therapy in Prostate Cancer ENSG00000117020 ENSG00000167749 ENSG00000129437 ENSG00000198793 ENSG00000169032 ENSG00000167755 PMC7767317__F3 Modulation of the Nrf2-vitagene pathway by H2S ENSG00000162711 ENSG00000178573 ENSG00000100387 ENSG00000096717 ENSG00000079999 PMC6715524__F4 Summary of histone PTM-mediated 53BP1 and BRCA1 DSB repair pathway choice regulation ENSG00000185513 ENSG00000012048 ENSG00000163961 ENSG00000011258 ENSG00000196591 PMC6049856__F1 CAD/POLD2 gene expression is associated with poor overall survival and chemoresistance in bladder urothelial carcinoma ENSG00000102967 ENSG00000084774 PMC11759867__F1 Action of eCIRP in hemorrhagic shock ENSG00000172936 ENSG00000136869 PMC9468507__F5 Methylation of genes and regulation of inflammatory processes on emotional response in young adults with alcoholic parents ENSG00000163568 ENSG00000132693 PMC9675387__F3 Oncology biosimilars: New developments and future directions ENSG00000187266 ENSG00000168610 PMC9376779__F4 Transcriptome changes in stages of non-alcoholic fatty liver disease ENSG00000242265 ENSG00000160097 ENSG00000105835 ENSG00000108551 ENSG00000173757 ENSG00000136997 ENSG00000160202 PMC8431582__F1 From Bipotent Neuromesodermal Progenitors to Neural-Mesodermal Interactions during Embryonic Development ENSG00000145147 ENSG00000065361 ENSG00000124205 ENSG00000125084 PMC5793761__F1 Bone morphogenetic protein (BMP) signaling pathway ENSG00000170365 ENSG00000137834 ENSG00000095739 ENSG00000198742 ENSG00000111341 ENSG00000164619 PMC3922160__F9 Proposed model integrating viral and host biomarkers for disease severity and the effect of IFNB in HAM/TSP ENSG00000177455 ENSG00000115415 ENSG00000130656 ENSG00000162924 ENSG00000049768 PMC7694276__F2 NcRNA involvement in thyroid cancer-related signaling pathways ENSG00000117020 ENSG00000134086 ENSG00000161921 ENSG00000173611 ENSG00000170558 ENSG00000198793 ENSG00000168036 ENSG00000053254 ENSG00000168615 ENSG00000159399 PMC6290322__F4 Moderate heat stress induces nerve growth factor (NGF) signaling including downstream activation of AKT and ERK as well as cyclic AMP responsive element-binding protein 1 (CREB1) transactivation ENSG00000070831 ENSG00000132478 PMC8657787__F1 Protein Tyrosine Phosphatases: Mechanisms in Cancer PMC4040598__F5 Model depicting effect of ADAM17 variant on the canonical TGFB signaling pathway PMC8657787__F3 Protein Tyrosine Phosphatases: Mechanisms in Cancer PMC9376779__F1 Transcriptome changes in stages of non-alcoholic fatty liver disease ENSG00000154342 ENSG00000125740 ENSG00000262785 ENSG00000065833 ENSG00000135218 ENSG00000130234 ENSG00000108551 ENSG00000140285 ENSG00000151365 ENSG00000099194 ENSG00000148339 ENSG00000173334 PMC7801189__F2 Mechanism of cytokine storm caused by SARS-CoV-2 ENSG00000137033 ENSG00000130234 ENSG00000125538 PMC9376779__F3 Transcriptome changes in stages of non-alcoholic fatty liver disease ENSG00000242265 ENSG00000169245 ENSG00000112972 ENSG00000129214 ENSG00000150907 ENSG00000113161 ENSG00000088926 ENSG00000140464 ENSG00000198911 ENSG00000132170 PMC3735707__F3 Maternal factors required for oocyte developmental competence in mice ENSG00000172680 ENSG00000082175 ENSG00000108055 ENSG00000133116 ENSG00000166278 ENSG00000167900 ENSG00000276876 PMC2417189__F8 Inhibition of neurogenesis and axis duplication by mkrn2 via PI3K/Akt signaling pathway ENSG00000075975 ENSG00000168036 PMC7220691__F4 KEGG pathway of pathways in small cell lung cancer ENSG00000145604 ENSG00000144063 ENSG00000189283 ENSG00000136997 ENSG00000123374 ENSG00000120868 ENSG00000164305 ENSG00000122008 PMC4131183__F3 TRAIL-induced apoptosis ENSG00000110514 ENSG00000158796 ENSG00000168040 PMC6905101__F5 Alkaloid extract of Corydalis yanhusuo inhibits angiogenesis via targeting vascular endothelial growth factor receptor signaling ENSG00000291971 ENSG00000168610 PMC9392297__F2 Toll-like receptors and their role in neuropathic pain and migraine ENSG00000174123 ENSG00000239732 ENSG00000172005 ENSG00000173039 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC6771225__F3 Rational combinations of PARPi with other targeted agents ENSG00000164430 ENSG00000198793 ENSG00000263042 ENSG00000146648 PMC7874138__F3 HCC cells by SIRT4 ENSG00000132109 ENSG00000198793 ENSG00000169710 ENSG00000118520 ENSG00000116906 ENSG00000089163 ENSG00000075239 ENSG00000168610 ENSG00000136826 PMC3779140__F3 DNA damage tolerance pathway (DDT): lesions (yellow Square) in the DNA template blocks progression of high-fidelity replicative polymerase resulting in stalled replication forks ENSG00000132646 ENSG00000162607 ENSG00000070950 ENSG00000130997 PMC7411231__F1 Regulatory interactions of the HSC model ENSG00000149311 ENSG00000168283 ENSG00000129757 ENSG00000162676 ENSG00000129355 ENSG00000168036 ENSG00000124762 PMC3779140__F4 Proposed model for TLS pathway ENSG00000132646 ENSG00000162607 ENSG00000070950 PMC3779140__F2 DNA damage signaling at replication forks ENSG00000188486 ENSG00000175054 ENSG00000164053 ENSG00000276618 PMC3779140__F5 TLS synthesis in ICL repair by Fanconi anemia (FA) pathway: replicative DNA polymerase stalls upon encounter of an interstrand crosslink (ICL) in DNA ENSG00000131944 ENSG00000012061 ENSG00000083093 ENSG00000154920 ENSG00000144554 ENSG00000188827 ENSG00000108384 ENSG00000115392 ENSG00000139618 PMC3916571__F7 The signaling transduction throughout integrin engagement by Cp aged under oxidative conditions ENSG00000291971 ENSG00000168036 ENSG00000099942 PMC7332542__F2 Genetic modifications for the establishment of a reductive, carbon dioxide fixing, and redox-neutral pathway from extracellular glycerol to extracellular SA in S ENSG00000146701 PMC3999169__F1 Roles for TNF-Receptor Associated Factor 3 (TRAF3) in Lymphocyte Functions ENSG00000131323 ENSG00000127191 PMC8663543__F1 CARDIOKIN1: Computational Assessment of Myocardial Metabolic Capability in Healthy Controls and Patients With Valve Diseases ENSG00000122966 ENSG00000172005 ENSG00000198670 ENSG00000154016 PMC6662509__F3 PPAR signaling pathway and DEGs.Abbreviation: DEGs, differentially expressed genes ENSG00000065833 ENSG00000150991 ENSG00000180432 ENSG00000100979 PMC7646253__F5 A3 activation of BER and MMR ENSG00000145321 PMC3555201__F3 HMGB1 in the tumor microenvironment and hypothesis of HMGB1 functioning via NF-kB and epigenetic pathways ENSG00000174744 ENSG00000173039 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000168610 PMC11495063__F4 Metabolic pathways enriched by DEGs between the EPG and PPG ENSG00000073578 ENSG00000117118 ENSG00000124370 ENSG00000139515 ENSG00000173599 ENSG00000213614 ENSG00000107789 PMC3594407__F8 Signaling pathway by which Beta-catenin may regulate intricate inflammatory responses in liver IRI ENSG00000143815 ENSG00000168610 PMC6458269__F1 In response to various stimuli such as infection or injury, mucosal epithelial barriers express a range of signals that ILC2s can integrate ENSG00000137033 ENSG00000146469 ENSG00000145777 ENSG00000166090 PMC7137211__F1 PI3K/AKT/mTOR axis and its alterations in breast cancer ENSG00000077782 PMC9523578__F1 Bacterial effectors mimicking ubiquitin-proteasome pathway tweak plant immunity ENSG00000157557 PMC7485553__F1 ACE and ACE2 in the pulmonary system and the tentative role of SARS-CoV-2The top right part of the figure shows the activation of the Spike (S)-protein of SARS-CoV-2 by predominantly TMPRSS2 and also other host proteases such as trypsin and furin ENSG00000140564 ENSG00000130234 ENSG00000184012 PMC8639577__F2 The PD‐1/PD‐L1 Signaling in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis: Recent Insights and Future Directions ENSG00000145604 ENSG00000291603 ENSG00000134982 ENSG00000198793 ENSG00000124181 ENSG00000141968 PMC4449713__F4 Unbreak My Heart: Targeting Mitochondrial Autophagy in Diabetic Cardiomyopathy ENSG00000177169 ENSG00000083290 PMC2423292__F6 Musashi1 signaling in mammary progenitor cell proliferation ENSG00000050165 ENSG00000168036 ENSG00000133961 ENSG00000114315 ENSG00000118971 ENSG00000135097 PMC4270133__F5 Applications of DRS ENSG00000139515 PMC4982223__F1 Signaling network of drug-induced glioma differentiation ENSG00000131095 ENSG00000168610 PMC4801359__F2 miTALOS v2: Analyzing Tissue Specific microRNA Function ENSG00000180210 ENSG00000134982 ENSG00000163914 PMC8509322__F3 Adaptive Mechanisms of Halophytes and Their Potential in Improving Salinity Tolerance in Plants ENSG00000115904 ENSG00000100485 ENSG00000105205 PMC9319223__F2 Assessing Drug-Induced Mitochondrial Toxicity in Cardiomyocytes: Implications for Preclinical Cardiac Safety Evaluation ENSG00000005381 ENSG00000106459 ENSG00000026103 PMC11397273__F4 Ubiquitination- and de-ubiquitination-regulating components related to milk fat synthesis ENSG00000090432 ENSG00000151726 ENSG00000169710 ENSG00000285482 ENSG00000099194 PMC11397273__F5 Model for the promotion of milk fat synthesis in dairy cow mammary cells through the ubiquitination pathway by soysterols and myristic acid ENSG00000135218 ENSG00000198793 ENSG00000169710 ENSG00000285482 PMC10779699__F2 Proposed model for the pathogenic role of the NLRP3 inflammasome signaling pathway in RA and its clinical implications as the therapeutic potential ENSG00000278718 ENSG00000162711 ENSG00000163661 ENSG00000137496 PMC7072717__F1 Store-operated Ca2+ entry pathway (SOCE) ENSG00000133107 ENSG00000144935 ENSG00000167323 ENSG00000293604 PMC8818415__F9 Bioinformatic Analysis of the Effect of the Sirtuin Family on Differentiated Thyroid Carcinoma ENSG00000149311 ENSG00000153487 ENSG00000179091 ENSG00000084774 PMC8150801__F1 Sex Hormone Receptor Signaling in Bladder Cancer: A Potential Target for Enhancing the Efficacy of Conventional Non-Surgical Therapy ENSG00000175054 ENSG00000041353 ENSG00000170558 ENSG00000150907 ENSG00000272398 ENSG00000168036 ENSG00000149554 ENSG00000146648 PMC5863151__F1 Estrogen pathway in lung carcinogenesis and its implications for targeted therapy ENSG00000146648 ENSG00000121966 PMC11049926__F4 General model of neuroinflammation in epilepsy ENSG00000169245 ENSG00000108691 ENSG00000111537 ENSG00000125538 PMC7767648__F4 Suppression of ARID1A associated with decreased CD8 T cells improves cell survival of ovarian clear cell carcinoma ENSG00000148400 ENSG00000095321 ENSG00000077522 ENSG00000162244 ENSG00000197457 ENSG00000100345 ENSG00000061794 ENSG00000112715 ENSG00000117713 ENSG00000109819 ENSG00000102081 ENSG00000149273 ENSG00000196712 ENSG00000154096 PMC8818415__F8 Bioinformatic Analysis of the Effect of the Sirtuin Family on Differentiated Thyroid Carcinoma ENSG00000198793 ENSG00000087842 PMC11988686__F2 Perilla frutescens terpene synthesis pathway; (B,C) P ENSG00000110921 ENSG00000197429 ENSG00000113161 ENSG00000167508 PMC8841724__F1 Targeting Tryptophan Catabolism in Cancer Immunotherapy Era: Challenges and Perspectives ENSG00000262635 ENSG00000188676 ENSG00000106546 PMC5726781__F4 MELK promotes melanoma growth by stimulating the NFKB pathway ENSG00000147649 ENSG00000275700 ENSG00000171720 ENSG00000284099 ENSG00000196591 ENSG00000196498 PMC5647180__F4 Identification of differentially regulated genes within the cellular assembly and organization, cellular function and maintenance and cell death and survival network ENSG00000140992 ENSG00000100591 ENSG00000101955 ENSG00000123545 ENSG00000188157 ENSG00000188229 ENSG00000139289 ENSG00000196642 ENSG00000081189 ENSG00000182253 PMC8784382__F2 Endoplasmic Reticulum Stress-Associated Neuronal Death and Innate Immune Response in Neurological Diseases ENSG00000128272 ENSG00000167207 ENSG00000144895 ENSG00000100219 ENSG00000127191 ENSG00000106100 ENSG00000168610 PMC5726781__F7 MELK promotes melanoma growth by stimulating the NFKB pathway ENSG00000157764 ENSG00000284099 ENSG00000196712 PMC2652397__F1 Dual Roles of Nrf2 in Cancer ENSG00000178573 ENSG00000100387 ENSG00000079999 PMC3265777__F2 Context-dependent regulation of Rho GTPase signaling ENSG00000114346 ENSG00000143878 ENSG00000164305 ENSG00000182541 PMC8473072__F7 MAPK/ERK Pathway and the Role of DUSP1 in JCPyV Infection of Primary Astrocytes ENSG00000177606 PMC10604999__F1 Scheme illustrating the main hippocampal mechanisms observed in the diabetes-related depression ENSG00000002330 ENSG00000145321 ENSG00000172936 ENSG00000136869 PMC7874138__F6 Breast cancer by SIRT4 ENSG00000089163 ENSG00000168610 PMC8717717__F2 Transcriptomic analysis of patient plasma reveals circulating miR200c as a potential biomarker for high-grade serous ovarian cancer ENSG00000163629 ENSG00000002745 ENSG00000151617 ENSG00000112715 ENSG00000121879 ENSG00000124181 ENSG00000123908 PMC6166072__F8 Phospholipase D signalling KEGG pathway indicating up‐ and down‐regulated differentially expressed genes in livers of male and female MO‐F1 vs ENSG00000033327 ENSG00000143761 ENSG00000010810 ENSG00000138798 ENSG00000198793 ENSG00000163914 ENSG00000198670 PMC7133421__F5 Graphical representation of the PI3K-Akt-mTORC1 signaling pathway PMC6166072__F6 Insulin signalling KEGG pathway indicating up‐ and down‐regulated differentially expressed genes in livers of male and female MO‐F1 vs ENSG00000171105 ENSG00000002330 ENSG00000005882 ENSG00000198793 ENSG00000026103 ENSG00000047932 PMC11976707__F2 Key molecular alterations and signaling pathways involved in the pathogenesis and progression of gastric cancer, along with selected targeted therapies (adapted from Lei et al ENSG00000066468 ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC8560752__F7 There might exist a constrained workflow model among ERA, ARSD, and Hippo/YAP pathway ENSG00000197905 ENSG00000007866 ENSG00000131023 ENSG00000074219 PMC6642231__F1 The folates and the one-carbon cycle (1-CC) ENSG00000228716 PMC7565347__F4 Molecular interactions of ZIKV and DENV with the type-I IFN pathway ENSG00000213928 ENSG00000187608 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC8245133__F6 The putative TAC-induced pathway that culminates in left ventricular hypertrophy ENSG00000187688 ENSG00000285109 ENSG00000103335 PMC4046017__F4 Inhibition of IFNg signaling by MAP ENSG00000102189 ENSG00000119383 PMC11705062__F4 Impact of lysine succinylation on signal transduction ENSG00000197747 ENSG00000148400 ENSG00000166147 PMC5810219__F5 Canonical Wnt pathway regulates gene expression by modulating Beta-catenin levels ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000155760 PMC6959120__F1 Simplified autophagy signaling pathway and regulation ENSG00000177169 ENSG00000198793 ENSG00000144848 ENSG00000112561 ENSG00000189298 ENSG00000145782 ENSG00000057663 PMC7904591__F1 Trained Immunity and Reactivity of Macrophages and Endothelial Cells ENSG00000162711 ENSG00000135218 ENSG00000167207 ENSG00000130164 ENSG00000198793 ENSG00000136869 ENSG00000079432 ENSG00000159399 ENSG00000140443 PMC8891570__F1 Contribution of Autophagy-Lysosomal Pathway in the Exosomal Secretion of Alpha-Synuclein and Its Impact in the Progression of Parkinson’s Disease ENSG00000123395 ENSG00000145782 PMC9024672__F2 Oxidative Stress and Ischemia/Reperfusion Injury in Kidney Transplantation: Focus on Ferroptosis, Mitophagy and New Antioxidants ENSG00000138449 ENSG00000181019 ENSG00000167468 ENSG00000167996 ENSG00000271303 ENSG00000023909 ENSG00000079999 PMC8376648__F8 Proposed working model ENSG00000023734 ENSG00000073792 PMC5445660__F2 Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras ENSG00000136492 ENSG00000114388 ENSG00000065911 ENSG00000140564 ENSG00000197312 ENSG00000119487 ENSG00000077152 ENSG00000198793 ENSG00000115392 ENSG00000187741 ENSG00000164327 ENSG00000112039 ENSG00000167965 ENSG00000158169 ENSG00000151092 ENSG00000106459 ENSG00000168003 ENSG00000198728 ENSG00000135363 ENSG00000159399 ENSG00000140443 ENSG00000198625 ENSG00000062485 PMC8718194__F2 Crosstalk between the caspase family and the cGAS‒STING signaling pathway ENSG00000183735 ENSG00000164430 ENSG00000125538 ENSG00000120868 PMC8718194__F1 Crosstalk between the caspase family and the cGAS‒STING signaling pathway ENSG00000164430 ENSG00000276561 PMC4377108__F2 Regulation of Molecular Pathways in Ischemia Reperfusion Injury after Liver Transplantation ENSG00000071564 ENSG00000149311 ENSG00000099330 ENSG00000175054 ENSG00000138795 ENSG00000144554 ENSG00000064393 ENSG00000136997 ENSG00000196628 ENSG00000080839 PMC3808753__F1 Coordinated action of glial and neuronal purinergic receptors and purines in the CNS ENSG00000128342 PMC7768132__F3 Regulatory mechanism of KRT19 expression in HCC ENSG00000019991 ENSG00000291971 ENSG00000138798 ENSG00000177606 ENSG00000134853 ENSG00000132478 ENSG00000146648 ENSG00000171345 PMC3428061__F2 Interface between hemostasis and adaptive immunity ENSG00000186810 ENSG00000145321 ENSG00000170989 ENSG00000163737 ENSG00000122194 PMC2923204__F2 Post-synaptic BDNF-TrkB Signaling in Synapse Maturation, Plasticity and Disease ENSG00000198793 ENSG00000198576 PMC11908050__F1 Glioblastoma signaling pathways ENSG00000177455 ENSG00000103479 ENSG00000065833 ENSG00000002330 ENSG00000186716 ENSG00000198793 PMC7789326__F4 SHMOs exerting anti-inflammatory effects in NEC ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC4163377__F1 MicroRNA and their involvement in oncologenic signaling cascades in pancreatic cancer ENSG00000157764 ENSG00000135446 ENSG00000198793 ENSG00000136997 ENSG00000168036 ENSG00000051180 ENSG00000105810 ENSG00000171791 ENSG00000146648 ENSG00000139618 PMC7270402__F1 Immune landscape of the HBV-based tumor microenvironment ENSG00000089692 ENSG00000134982 PMC5855642__F1 Sphingolipid signaling pathway ENSG00000213694 PMC4618289__F1 MTOR pathway as a central signaling pathway causing malformations of cortical development and epilepsy ENSG00000114388 PMC5855642__F2 Transformation of SphK/S1P/S1PRs signaling ENSG00000170989 ENSG00000213694 PMC7780621__F3 Role of cytokines/chemokines on tumor progression and dissemination ENSG00000107562 ENSG00000126353 ENSG00000112715 ENSG00000121966 ENSG00000150630 PMC4125008__F1 current targets of nuclear DNA repair pathway proteins and their functions ENSG00000143799 ENSG00000170430 ENSG00000051180 ENSG00000095002 ENSG00000136936 PMC8997978__F4 Label-Free LC-MS/MS Analysis Reveals Different Proteomic Profiles between Egg Yolks of Silky Fowl and Ordinary Chickens ENSG00000139574 PMC6033950__F6 EE2 and LNG affected the phosphorylation of proteins involved in brain development, synaptic plasticity, neurogenesis, synaptic transmission, and calcium ion homeostasis although the specific phosphorylation profiles varied ENSG00000008710 ENSG00000134982 ENSG00000176788 ENSG00000049618 ENSG00000253117 ENSG00000180104 ENSG00000188372 ENSG00000074800 ENSG00000148408 ENSG00000148773 ENSG00000197971 ENSG00000143379 ENSG00000171951 ENSG00000100625 ENSG00000169375 ENSG00000155657 ENSG00000118058 ENSG00000145362 ENSG00000171320 ENSG00000005339 ENSG00000085552 ENSG00000073756 ENSG00000081189 ENSG00000173546 ENSG00000169220 ENSG00000065526 ENSG00000196218 ENSG00000196689 ENSG00000115155 ENSG00000120594 ENSG00000080839 PMC6885271__F5 Proposed schematic diagram of LPS-induced ROS-mediated neuroinflammation, neurodegeneration, and memory deficits via dysregulation of the JNK/NFKB/Akt signaling pathway ENSG00000125538 ENSG00000131095 ENSG00000132639 PMC5408006__F3 Toll-like receptor signaling pathways ENSG00000174123 ENSG00000174125 ENSG00000239732 ENSG00000109320 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000276561 ENSG00000164342 PMC7565446__F3 Thyroid hormone synthesis pathway (modified from hsa04918) ENSG00000042832 ENSG00000140279 ENSG00000123104 ENSG00000127022 ENSG00000140274 ENSG00000182621 ENSG00000161944 ENSG00000116830 ENSG00000137841 ENSG00000091137 ENSG00000087460 ENSG00000163631 ENSG00000164742 ENSG00000128272 ENSG00000174233 ENSG00000167468 ENSG00000166501 ENSG00000155660 ENSG00000165409 ENSG00000162104 ENSG00000134200 ENSG00000101333 PMC2519632__F6 Proposed model of KSHV-induced lymphatic reprogramming of endothelial cells ENSG00000117707 ENSG00000168610 PMC6089768__F11 miRNA-145 inhibits myocardial infarction-induced apoptosis through autophagy by Akt3/mTOR signaling pathway in viv and in vitro ENSG00000117020 ENSG00000198793 ENSG00000057663 PMC8167159__F2 Strategies to tackle RAS-mutated metastatic colorectal cancer ENSG00000135446 ENSG00000138798 ENSG00000198793 ENSG00000105810 ENSG00000146648 PMC3997659__F1 Role of Ub and SUMO modification of PCNA ENSG00000132646 ENSG00000070950 ENSG00000166169 PMC7734173__F1 Endosomal and cytosolic DNA sensors and their related signaling pathways ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000163568 ENSG00000174953 ENSG00000276561 PMC7718081__F8 Chronic ethanol exposure on the expression of GLT-1 and neuroplasticity-related proteins in the nucleus accumbens of alcohol-preferring rats ENSG00000198576 ENSG00000189403 PMC3549535__F3 Innate immune stimulation by LPS positively impacts T cell priming ENSG00000172936 ENSG00000136869 PMC4451963__F1 Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC5540157__F1 The Shh signaling pathway ENSG00000134057 ENSG00000291971 ENSG00000164690 ENSG00000128602 PMC11727972__F6 Bile acids (BAs) regulate cancers via the farnesoid X receptor (FXR) ENSG00000137673 ENSG00000291971 ENSG00000198793 ENSG00000168610 ENSG00000146648 ENSG00000145113 PMC6125328__F1 Signaling via MALT1 downstream of various receptors and CARMA/CARD proteins ENSG00000170909 ENSG00000187796 ENSG00000291971 ENSG00000186716 ENSG00000083799 PMC6125328__F4 CARMA/CARD-dependent and-independent MALT1 activation ENSG00000163599 ENSG00000186716 ENSG00000197943 ENSG00000124181 PMC8402453__F4 Promise and Challenges of Cyclic Dinucleotides as Molecular Adjuvants for Vaccine Development ENSG00000183735 ENSG00000164430 PMC4546272__F3 Impaired Cell Cycle Regulation in a Natural Equine Model of Asthma ENSG00000145604 ENSG00000068028 ENSG00000134982 ENSG00000123374 ENSG00000166851 ENSG00000117399 ENSG00000062485 PMC9412366__F2 Antibody-Dependent Enhancement: ″Evil″ Antibodies Favorable for Viral Infections ENSG00000162711 ENSG00000183735 ENSG00000213928 ENSG00000105397 PMC3795378__F2 Tumor (SVZ) micro-environment ENSG00000107562 ENSG00000164690 PMC7113505__F2 microRNA (miRNA)–gene–pathway network based on miRTarBase and WikiPathways as described in the Methods section ENSG00000087095 ENSG00000112576 ENSG00000171105 ENSG00000105329 ENSG00000169710 ENSG00000168036 ENSG00000171791 ENSG00000112715 ENSG00000168610 ENSG00000177426 ENSG00000066336 ENSG00000115415 ENSG00000198742 ENSG00000135446 ENSG00000128052 ENSG00000136997 ENSG00000150907 ENSG00000119396 ENSG00000077782 PMC8998820__F4 Natterin-Induced Neutrophilia Is Dependent on cGAS/STING Activation via Type I IFN Signaling Pathway ENSG00000164430 ENSG00000125538 ENSG00000174885 ENSG00000172936 ENSG00000091106 PMC3429585__F1 DKK1 as a novel target for myeloma immunotherapy ENSG00000126353 ENSG00000112486 PMC8588554__F7 Diterpenoid Compounds Isolated from Chloranthus oldhamii Solms Exert Anti-Inflammatory Effects by Inhibiting the IKK/NFKB Pathway ENSG00000170458 ENSG00000173599 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC6521797__F2 Siglec-7 mediated inhibition of NK cell cytotoxicity towards tumor cells ENSG00000291971 ENSG00000231179 ENSG00000204520 PMC5752241__F6 The WNT signaling pathway activated by PRP ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000131196 PMC7493839__F3 Application of CRISPR-Cas9 in construction of TCR and CAR T-cells ENSG00000089692 ENSG00000163599 ENSG00000273686 ENSG00000026103 PMC11310285__F1 Hypoxia signaling pathway ENSG00000134086 PMC3077564__F3 Activation of glia and neurons in the dorsal horn of the spinal cord after peripheral injury ENSG00000168329 ENSG00000108691 ENSG00000121807 PMC11310285__F2 Hypoxia pathway proteins-microRNA-phosphodiesterase crosstalk in steroidogenesis regulation ENSG00000176387 PMC11889408__F1 IL-6 family cytokine signaling pathway ENSG00000187682 ENSG00000099985 ENSG00000242689 ENSG00000198793 ENSG00000128342 ENSG00000168610 PMC12073115__F4 Mammalian RNA-dependent mRNA amplification is enabled by the integrated stress response ENSG00000128272 ENSG00000162600 ENSG00000169136 ENSG00000081791 PMC7004969__F1 Selected important players of osteoblast differentiation ENSG00000178860 ENSG00000152266 ENSG00000050165 PMC11997338__F9 Working model showing a positive role of DSP in the migration and endothelial differentiation of DPSCs through DSPaa34–50–ENGZP association and subsequent activation of AKT1 signaling pathway ENSG00000167772 ENSG00000113296 PMC8957861__F1 How the Innate Immune System of the Blood Contributes to Systemic Pathology in COVID-19-Induced ARDS and Provides Potential Targets for Treatment ENSG00000122194 ENSG00000132693 PMC8423996__F2 GDF15: an emerging modulator of immunity and a strategy in COVID-19 in association with iron metabolism ENSG00000130234 PMC4117634__F9 Macrophage-Activating Lipopeptide-2 Requires Mal and PI3K for Efficient Induction of Heme Oxygenase-1 ENSG00000172005 ENSG00000172936 ENSG00000010671 ENSG00000079999 PMC6428452__F8 p38gamma MAPK-promoted EMT ENSG00000107485 ENSG00000178691 ENSG00000178568 PMC12210305__F6 High-temperature stored soybean meal on MAPK and FOXO signaling pathways in broiler jejunum tissue ENSG00000087095 ENSG00000171444 ENSG00000102871 ENSG00000179091 ENSG00000130522 ENSG00000138798 ENSG00000126457 ENSG00000127528 ENSG00000130159 ENSG00000115718 ENSG00000168610 ENSG00000081189 ENSG00000145604 ENSG00000149311 ENSG00000170458 ENSG00000123374 ENSG00000026103 PMC4646664__F1 Abnormal Protein Glycosylation and Activated PI3K/Akt/mTOR Pathway: Role in Bladder Cancer Prognosis and Targeted Therapeutics PMC7033549__F9 A working model depicting the relationship between proline and polyamine in wild type, PvP5CS OE and RNAi transgenic plants under control and salt stress conditions ENSG00000100033 PMC3726361__F4 Focal adhesion signaling pathway highlighting those genes that are differentially expressed compared to untreated control ovaries and identifying by color the treatment group(s) from which the differentially expressed genes came ENSG00000002330 ENSG00000175193 ENSG00000010810 ENSG00000177606 PMC4994475__F1 Network of reported candidate genes associated with GTS ENSG00000140287 ENSG00000178235 ENSG00000179915 ENSG00000183826 ENSG00000106852 ENSG00000114686 ENSG00000276825 ENSG00000159200 ENSG00000116544 ENSG00000159197 ENSG00000184845 ENSG00000143801 ENSG00000136997 PMC3304298__F1 AKT signaling pathway ENSG00000177455 ENSG00000033327 ENSG00000002330 ENSG00000069482 ENSG00000186716 ENSG00000198793 ENSG00000169047 ENSG00000164327 ENSG00000276876 PMC9277406__F1 Liposomal irinotecan (Onivyde): Exemplifying the benefits of nanotherapeutic drugs ENSG00000134982 PMC3518872__F4 Three IPA Canonical Signaling Pathways: CD40, IL-1, and Chemokine Signaling in TGFB1+LPS+IFNGamma-treated astrocytes ENSG00000162889 ENSG00000183625 ENSG00000132478 ENSG00000130159 ENSG00000104921 ENSG00000127191 ENSG00000168610 ENSG00000121966 ENSG00000226275 ENSG00000163914 ENSG00000082512 ENSG00000056558 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000123268 PMC2726075__F1 EGFR signaling pathway ENSG00000138798 ENSG00000136997 PMC2766677__F7 Proposed scheme of the signaling pathway leading to immature dendritic cell chemotaxis upon exposure to M-tropic gp120 PMC3518872__F3 Top three networks of significantly associated molecules in TGFB1+LPS+IFNGamma-treated astrocytes ENSG00000179750 ENSG00000196743 ENSG00000171209 ENSG00000126003 ENSG00000080546 ENSG00000176953 ENSG00000281165 ENSG00000241258 ENSG00000119138 ENSG00000171467 ENSG00000291480 ENSG00000159055 ENSG00000086475 ENSG00000113761 ENSG00000103647 ENSG00000107833 ENSG00000185090 ENSG00000170633 ENSG00000177548 ENSG00000198478 ENSG00000163788 ENSG00000142552 ENSG00000275543 ENSG00000104689 ENSG00000108515 ENSG00000138311 ENSG00000166278 ENSG00000048392 ENSG00000173221 ENSG00000058600 ENSG00000084636 ENSG00000075218 ENSG00000047410 ENSG00000184185 ENSG00000129422 ENSG00000172315 ENSG00000140961 ENSG00000132676 ENSG00000131669 ENSG00000107186 ENSG00000092621 ENSG00000197386 ENSG00000163681 ENSG00000189067 ENSG00000168209 ENSG00000166257 ENSG00000116729 ENSG00000181026 ENSG00000123360 ENSG00000063015 ENSG00000138135 ENSG00000116649 PMC3518872__F6 GPCR Canonical Signaling Pathways ENSG00000150594 ENSG00000152495 ENSG00000291971 PMC491841__F1 Consensus model of the cell cycle control mechanism in budding yeast ENSG00000175854 ENSG00000136425 ENSG00000134982 ENSG00000117399 PMC7311199__F3 DNA-stimulated cell death: implications for host defence, inflammatory diseases and cancer ENSG00000278718 ENSG00000162711 ENSG00000183735 ENSG00000164430 ENSG00000137275 ENSG00000163568 ENSG00000168404 ENSG00000285379 PMC5122382__F9 Dual PI3K- and mTOR-inhibitor PI-103 can either enhance or reduce the radiosensitizing effect of the Hsp90 inhibitor NVP-AUY922 in tumor cells: The role of drug-irradiation schedule ENSG00000135446 ENSG00000198793 PMC5746573__F2 Ca2+ and ROS crosstalk between ER and mitochondria, with emphasis on redox control of the MCU ENSG00000156026 PMC11915041__F4 Research progress on the role of decorin in the development of oral mucosal carcinogenesis ENSG00000100234 ENSG00000112715 ENSG00000140443 PMC5346035__F1 PharmGKB summary: macrolide antibiotic pathway, pharmacokinetics/pharmacodynamics ENSG00000229314 ENSG00000023839 PMC7015241__F10 Working model describing how MYPN and PALLD may promote SRF signalling ENSG00000138347 PMC3545835__F1 Principal platelet membrane receptors and signal transduction pathways ENSG00000110799 ENSG00000197943 PMC3669920__F1 Schematic of neuregulin-ERBB4 signaling showing the roles of the products of the selected genes ENSG00000138798 ENSG00000178568 PMC6056829__F1 GPI biosynthesis in yeast ENSG00000167701 PMC5393394__F5 Network analysis for the RS fraction proteins with increased secretion upon intracellular LPS stimulation ENSG00000203747 ENSG00000170458 ENSG00000117601 ENSG00000273686 ENSG00000197045 PMC9317051__F3 Resistance and Implications for Treatment Strategies in Chronic Myeloid Leukaemia ENSG00000033327 ENSG00000186716 ENSG00000198793 ENSG00000168036 ENSG00000099942 ENSG00000128602 ENSG00000168610 PMC3269020__F3 Role of miRNAs in aging of mice ENSG00000185591 ENSG00000171791 ENSG00000096717 ENSG00000140443 PMC3269020__F1 Pathways involved in aging ENSG00000065559 ENSG00000140443 ENSG00000106459 ENSG00000167186 PMC5422712__F8 CD40-mediated apoptosis in carcinoma cells ENSG00000056558 ENSG00000131323 PMC9936654__F10 Transcriptome analysis of Populus × canadensis ‘Zhongliao1’ in response to low temperature stress ENSG00000012061 ENSG00000105486 ENSG00000292191 ENSG00000100387 ENSG00000132646 ENSG00000277273 ENSG00000134480 ENSG00000136936 PMC11722408__F2 Mesenchymal Phenotypes Utilize Autocrine and Paracrine Signaling to Reinforce SCLC Subtypes ENSG00000167601 ENSG00000168913 ENSG00000157404 ENSG00000138798 ENSG00000173482 ENSG00000060138 ENSG00000173546 ENSG00000105894 ENSG00000076554 ENSG00000118785 ENSG00000188157 ENSG00000177606 ENSG00000158887 ENSG00000117335 ENSG00000185591 ENSG00000114315 ENSG00000198910 ENSG00000133027 PMC10379601__F5 Hypocholesterolemic Potential of the Edible Algae Fucus vesiculosus: Proteomic and Quantitative PCR Analysis ENSG00000132196 ENSG00000001630 ENSG00000116133 ENSG00000172893 PMC11098888__F4 CCL1/CCR8, CCL3/CCR5, CXCL6/CXCR2, and CXCL12/ CXCR4 axes in esophageal squamous cell carcinoma ENSG00000108702 ENSG00000179934 ENSG00000107562 ENSG00000069482 ENSG00000291971 ENSG00000163914 ENSG00000124875 ENSG00000121966 PMC5554756__F3 Negative regulators of the RIG-I-like receptor signaling pathway ENSG00000135655 ENSG00000088888 ENSG00000000003 ENSG00000160703 ENSG00000131323 ENSG00000166851 ENSG00000101695 PMC5554756__F1 Negative regulators of the RIG-I-like receptor signaling pathway ENSG00000135655 ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000175104 ENSG00000121060 ENSG00000141569 PMC5554756__F2 Negative regulators of the RIG-I-like receptor signaling pathway ENSG00000135655 ENSG00000213186 ENSG00000133874 ENSG00000088888 ENSG00000167207 ENSG00000214087 ENSG00000140455 ENSG00000036672 ENSG00000204977 ENSG00000155313 ENSG00000121060 ENSG00000101695 PMC7381287__F1 LPS signaling ENSG00000183735 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC11979484__F9 Hi-Exos in relieving the senescence of NPCs and IDD ENSG00000168209 ENSG00000123908 PMC10458661__F2 TLR and RLR signaling pathways present in airway epithelial cells in response to viral infections ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC2934757__F1A Defining the pathway to insulin-like growth factor system targeting in cancer ENSG00000197081 ENSG00000169047 ENSG00000140443 PMC3720640__F3 Anti-Epidermal Growth Factor Receptor Therapy in Head and Neck Squamous Cell Carcinoma: Focus on Potential Molecular Mechanisms of Drug Resistance ENSG00000291971 ENSG00000105426 PMC5184782__F1 Context-dependent TGFB signaling pathway ENSG00000259207 ENSG00000291971 ENSG00000173517 ENSG00000126778 PMC171388__F7 Model of Cripto’s inhibition of Act B signaling through the Smad2 pathway ENSG00000241186 ENSG00000156574 PMC10380015__F2 Challenges and Future Trends in Atopic Dermatitis ENSG00000137033 ENSG00000136694 ENSG00000172936 ENSG00000175104 ENSG00000115594 ENSG00000137496 PMC10380015__F3 Activation of the adaptive immune system via various receptors, different interleukins and its receptors, and the Janus kinases (JAK) STAT pathway ENSG00000138378 ENSG00000123496 ENSG00000104321 ENSG00000105397 ENSG00000115415 ENSG00000145777 ENSG00000131724 ENSG00000105639 ENSG00000168610 ENSG00000010671 ENSG00000106546 PMC6580124__F7 Mechanism of rapamycin’s anti-angiogenic and anti-lymphangiogenic effects in melanoma ENSG00000165197 ENSG00000198793 ENSG00000112715 ENSG00000150630 PMC7915726__F1 The Mer receptor tyrosine kinase (MERTK)-mediated signaling pathway in epidermal growth factor tyrosine kinase inhibitors (EGFR-TKI) resistance ENSG00000019991 ENSG00000153208 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000168610 ENSG00000146648 ENSG00000184500 PMC6667871__F8 Schematic model depicting the mechanism of DEPDC1-induced HCC progression ENSG00000024526 ENSG00000115009 ENSG00000112486 PMC7915726__F5 MERTK in Yes-associated protein (YAP)-mediated EGFR-TKI resistance ENSG00000138798 ENSG00000114978 ENSG00000146648 PMC3627331__F1 CD30 signals through TRAFs: upon stimulation by CD30L, CD30 recruits TRAF2 via interaction with its TRAF binding motif, resulting in TRAF2 degradation ENSG00000104856 ENSG00000102871 ENSG00000131323 ENSG00000127191 PMC6513092__F7 PIN1and PTOV1 pathway interactions ENSG00000127445 ENSG00000104960 ENSG00000134057 ENSG00000168036 PMC6315738__F1 Intestinal uptake of non-heme iron and its regulation ENSG00000182511 ENSG00000089472 PMC12090806__F7 Role of TRIM22 in antiviral immunity ENSG00000163435 ENSG00000183735 ENSG00000088888 ENSG00000160703 PMC5706953__F1 KEAP1 glycosylation regulates the NRF2 pathway ENSG00000147162 ENSG00000151012 ENSG00000181019 ENSG00000198408 ENSG00000023909 ENSG00000079999 PMC4446875__F10 Schematic diagram depicting the conceivable cellular events by which MIOX disrupts mitochondrial integrity under HG ambience, which results in renal tubular cell injury ENSG00000100253 ENSG00000116688 ENSG00000158828 ENSG00000214253 PMC126171__F5 Different telomere damage signaling pathways in human and mouse cells ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC6171574__F3 Signal transduction initiated by transforming growth factorB1 (TGFB1) ENSG00000168487 PMC6037039__F4 Functional mechanisms of lncRNAs in vascular disease ENSG00000185818 ENSG00000155506 ENSG00000170961 ENSG00000115008 ENSG00000197757 ENSG00000168589 ENSG00000127528 ENSG00000253352 ENSG00000112715 ENSG00000147262 PMC4150931__F1 Signaling pathways that induce epithelial–mesenchymal transition (EMT) ENSG00000163914 ENSG00000154059 PMC4124648__F2 Possible therapeutic interventions on molecular mechanism inducing necrotizing enterocolitis ENSG00000138798 ENSG00000189403 ENSG00000136869 PMC8026578__F2 MicroRNAs in the pathophysiology of addiction ENSG00000164742 ENSG00000166501 ENSG00000127955 ENSG00000143933 ENSG00000169032 ENSG00000120251 ENSG00000186298 ENSG00000291420 ENSG00000087460 PMC10298332__F4 The TNF signalling pathway by M-glucans ENSG00000167207 ENSG00000078747 ENSG00000102871 ENSG00000157227 ENSG00000164400 ENSG00000007908 ENSG00000128342 ENSG00000168040 ENSG00000168404 ENSG00000125347 ENSG00000164305 PMC6391339__F1 Biogenesis of miRNAs ENSG00000092847 ENSG00000172795 ENSG00000128191 ENSG00000113360 ENSG00000132341 PMC10298332__F5 The C-type lectin pathway by M-glucans ENSG00000104856 ENSG00000102962 ENSG00000102970 ENSG00000083799 ENSG00000125347 PMC8615411__SF1 Synthesis and Biological Evaluation of D-Ring-Modified Vitamin D Analogues ENSG00000019186 ENSG00000186104 ENSG00000135929 PMC9326176__F2 Cathepsin K+ Non-Osteoclast Cells in the Skeletal System: Function, Models, Identity, and Therapeutic Implications ENSG00000107779 ENSG00000163501 ENSG00000168610 ENSG00000143387 PMC10298332__F6 The IL-17 signalling pathway by M-glucans ENSG00000111537 ENSG00000171444 ENSG00000163220 ENSG00000157625 ENSG00000131323 ENSG00000100985 ENSG00000168040 ENSG00000056736 ENSG00000155313 ENSG00000175104 ENSG00000163702 ENSG00000076604 PMC9623337__F1 New insights into Chlamydia pathogenesis: Role of leukemia inhibitory factor ENSG00000128342 ENSG00000168610 PMC4729089__F1 Metabolic pathway of monoamine neurotransmitter synthesis and degradation ENSG00000171759 PMC3897220__F9 Concept map of Whi5 function ENSG00000101751 ENSG00000135517 PMC6216037__F8 Oxidative stress-induced autophagy and endothelial dysfunction ENSG00000094631 ENSG00000171791 PMC10951504__F5 Underlying mechanism of obesity and hyperuricemia ENSG00000108691 ENSG00000177606 ENSG00000143839 ENSG00000115138 ENSG00000132693 ENSG00000163631 ENSG00000167701 PMC5087126__F2 Innate immune memory and homeostasis may be conferred through crosstalk between the TLR3 and TLR7 pathways ENSG00000104856 ENSG00000213928 ENSG00000102871 ENSG00000108342 ENSG00000168610 ENSG00000276561 ENSG00000183735 ENSG00000105397 ENSG00000157625 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC10951504__F6 Associations between obesity and hyperuricemia combing mendelian randomization with network pharmacology ENSG00000102871 ENSG00000198793 ENSG00000115138 ENSG00000127191 ENSG00000168610 PMC7316587__F2 Molecular mechanisms proposed for NHE isoforms in cancer ENSG00000019991 ENSG00000070831 ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC8387950__F8 FABP3 Deficiency Exacerbates Metabolic Derangement in Cardiac Hypertrophy and Heart Failure via PPARA Pathway PMC8088471__F7 Periodontitis‐compromised dental pulp stem cells secrete extracellular vesicles carrying miRNA‐378a promote local angiogenesis by targeting Sufu to activate the Hedgehog/Gli1 signalling PMC11873051__F1 Resistance mechanisms to CDK4/6 inhibitors ENSG00000083857 ENSG00000066468 ENSG00000135446 ENSG00000087586 ENSG00000123374 ENSG00000105810 ENSG00000077782 ENSG00000196712 PMC6536409__F7 LncRNA TNRC6C‐AS1 facilitated cell proliferation and inhibits cell apoptosis and autophagy by promoting the methylation of STK4 promoter region via the Hippo signalling pathway ENSG00000101109 ENSG00000088305 ENSG00000150457 ENSG00000131023 PMC8999734__F4 Anti-Inflammatory Activities of an Anti-Histamine Drug, Loratadine, by Suppressing TAK1 in AP-1 Pathway ENSG00000149968 ENSG00000172936 ENSG00000136869 ENSG00000100985 PMC6148449__F1 SRP54 and a need for a new neutropenia nosology ENSG00000167881 ENSG00000140319 ENSG00000100883 ENSG00000153037 ENSG00000140598 ENSG00000143742 ENSG00000242372 PMC6127670__F7 Obesity-mediated regulation of cardiac protein acetylation: parallel analysis of total and acetylated proteins via TMT-tagged mass spectrometry ENSG00000105993 ENSG00000073578 ENSG00000132622 ENSG00000100412 ENSG00000278461 ENSG00000137270 ENSG00000132478 ENSG00000105953 ENSG00000110435 ENSG00000091140 ENSG00000062485 PMC9253705__F40 Pexmetinib suppresses osteoclast formation and breast cancer induced osteolysis via P38/STAT3 signal pathway ENSG00000087245 ENSG00000168610 ENSG00000131196 ENSG00000143387 PMC11921819__F4 Ferroptosis in Tumor Immunity ENSG00000168003 ENSG00000135218 ENSG00000151012 ENSG00000167468 PMC2014644__F2 PGE2-EP receptor signaling pathways ENSG00000168036 ENSG00000146648 PMC11921819__F5 Cuproptosis in Tumor Immunity ENSG00000108691 ENSG00000164430 ENSG00000138131 ENSG00000115415 ENSG00000189403 ENSG00000168610 ENSG00000142166 PMC11921819__F1 Molecular mechanisms and crosstalk among five cell death modalities: Apoptosis, Necroptosis, Pyroptosis, Ferroptosis, and Cuproptosis ENSG00000121897 ENSG00000162711 ENSG00000124256 ENSG00000182511 ENSG00000167468 ENSG00000111684 ENSG00000120868 ENSG00000168040 ENSG00000127191 ENSG00000073605 PMC6371813__F1 Protein synthesis and degradation pathways in skeletal muscle ENSG00000150907 ENSG00000169047 PMC7551806__F1 Putative molecular mechanisms involved in the development of sarcopenia during aging ENSG00000198793 ENSG00000140443 PMC3190192__F1 PRL crosstalk with estrogen, progesterone, EGF/TGFA, and IGF-I ENSG00000163235 ENSG00000138798 PMC11792170__F2 Part of IL-27 signaling pathways in obesity and other related metabolic diseases ENSG00000134982 ENSG00000198793 ENSG00000168610 PMC7557985__F1 Involvement of p38 MAPK, ERK MAPK, and NFKB signaling pathways in osteoclast differentiation mediated by RANKL and BMP2 ENSG00000164935 PMC7139475__F5 Antidepressant Effects of Scutellaria baicalensis, Hericium erinaceus and Rhodiola rosea ENSG00000087085 ENSG00000168610 PMC7139475__F2 Antidepressant Effects of Scutellaria baicalensis, Hericium erinaceus and Rhodiola rosea ENSG00000162711 ENSG00000006712 ENSG00000125538 ENSG00000118515 ENSG00000077279 ENSG00000096717 PMC8869474__F1 Tipping the Balance: Vitamin D Inadequacy in Children Impacts the Major Gut Bacterial Phyla ENSG00000111012 ENSG00000172893 ENSG00000019186 ENSG00000186104 PMC3347988__F4 Schematic overview of the pathway controlling translational changes in adipogenesis ENSG00000101751 ENSG00000136997 ENSG00000166169 PMC3717195__F1 DNA repair systems ENSG00000012061 ENSG00000143799 ENSG00000164053 ENSG00000039650 ENSG00000112130 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000105486 ENSG00000134574 ENSG00000076924 ENSG00000132646 ENSG00000165392 ENSG00000167986 ENSG00000137074 ENSG00000051180 ENSG00000042088 ENSG00000227345 ENSG00000136936 PMC8564965__F2 Fibroblast growth factor receptor fusions in cancer: opportunities and challenges ENSG00000168610 PMC8130302__F2 Effects of locomotion on bone marrow mesenchymal stem cell fate: insight into mechanical regulation and bone formation ENSG00000087095 ENSG00000138795 ENSG00000169071 ENSG00000163914 ENSG00000168036 PMC11792170__F1 Some immune cells regulated by IL-27 ENSG00000138378 ENSG00000115415 ENSG00000107485 ENSG00000105246 ENSG00000168610 ENSG00000026103 PMC6208373__F7 Toll-like receptor signalling pathway shows similarities, but also differences between LPS and LPS + IFNG ENSG00000174125 ENSG00000170458 ENSG00000131323 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000135517 ENSG00000143387 PMC6410520__F1 Microbial-based production of nutraceuticals from simple carbon sources ENSG00000197429 PMC9026333__F6 Heparan Sulfate, Mucopolysaccharidosis IIIB and Sulfur Metabolism Disorders ENSG00000110395 ENSG00000116761 PMC4870992__F2 Pathogenesis of Hepatocellular Carcinoma ENSG00000136997 ENSG00000164362 PMC4110660__F2 In silico network and pathway enrichment analysis ENSG00000182481 ENSG00000100591 ENSG00000100519 ENSG00000145687 ENSG00000178951 ENSG00000112972 ENSG00000124789 ENSG00000165480 ENSG00000100883 ENSG00000161405 ENSG00000196591 ENSG00000127511 ENSG00000113569 ENSG00000113851 ENSG00000012048 ENSG00000150991 ENSG00000077254 ENSG00000126803 ENSG00000136997 ENSG00000162521 ENSG00000101191 ENSG00000106348 ENSG00000103266 ENSG00000005339 ENSG00000095059 ENSG00000179222 ENSG00000141956 ENSG00000198298 ENSG00000170142 ENSG00000158290 ENSG00000108179 ENSG00000138336 ENSG00000065526 ENSG00000134057 ENSG00000175166 ENSG00000167986 ENSG00000139842 ENSG00000108671 ENSG00000069345 ENSG00000136205 ENSG00000102974 ENSG00000189079 PMC7766597__F1 Four different types of regulated cell death ENSG00000162711 ENSG00000102871 ENSG00000163568 ENSG00000167468 ENSG00000091592 ENSG00000168404 ENSG00000026103 PMC6526899__F3 Cmah deficiency may lead to age-related hearing loss by influencing miRNA-PPAR mediated signaling pathway ENSG00000039537 ENSG00000147684 ENSG00000179091 ENSG00000117118 ENSG00000126267 ENSG00000163541 ENSG00000166136 ENSG00000178127 ENSG00000267855 ENSG00000139180 ENSG00000136521 ENSG00000127540 ENSG00000173992 ENSG00000131174 ENSG00000109390 ENSG00000128609 ENSG00000213619 ENSG00000065518 ENSG00000151366 ENSG00000184076 ENSG00000110717 ENSG00000119013 ENSG00000105379 ENSG00000062485 PMC6526899__F4 Cmah deficiency may lead to age-related hearing loss by influencing miRNA-PPAR mediated signaling pathway ENSG00000116898 ENSG00000113889 ENSG00000183486 ENSG00000198015 ENSG00000242485 ENSG00000143436 ENSG00000055955 ENSG00000138430 ENSG00000132300 ENSG00000185414 ENSG00000157184 ENSG00000178537 ENSG00000175198 ENSG00000137992 ENSG00000114054 ENSG00000262814 ENSG00000291555 PMC6555965__F1 Schematic diagram of lipid biosynthesis pathway in Schizochytrium sp ENSG00000122966 ENSG00000172005 ENSG00000026103 PMC6526899__F2 Cmah deficiency may lead to age-related hearing loss by influencing miRNA-PPAR mediated signaling pathway ENSG00000111530 ENSG00000171033 ENSG00000214013 ENSG00000079156 ENSG00000069667 ENSG00000084774 PMC4178034__F3 Thermal Stress Triggers Broad Pocillopora damicornis Transcriptomic Remodeling, while Vibrio coralliilyticus Infection Induces a More Targeted Immuno-Suppression Response ENSG00000172936 ENSG00000175104 ENSG00000101425 PMC3724874__F7 Propyl-2-(8-(3,4-Difluorobenzyl)-2′,5′-Dioxo-8-Azaspiro[Bicyclo[3.2.1] Octane-3,4′-Imidazolidine]-1′-yl) Acetate Induces Apoptosis in Human Leukemia Cells through Mitochondrial Pathway following Cell Cycle Arrest ENSG00000002330 ENSG00000171791 PMC6636202__F8 Illustration of the miR-153 gene pathway in bladder cancer cells ENSG00000168610 PMC3213081__F1 The P2X7 Receptor in Infectious Diseases ENSG00000162711 ENSG00000172216 ENSG00000125538 ENSG00000118520 PMC3162452__F7 Schematic representation of intracellular pathways implicated in the regulation of cholesterol homeostasis and inflammatory response in human macrophages by IL-6 ENSG00000168610 PMC5922990__F9 Antiviral properties of naringenin ENSG00000113161 PMC5954269__F1 Vitamin D Pathways: An Overview (source: Nutrients 2016, 8, 319) ENSG00000111012 ENSG00000152266 ENSG00000105516 ENSG00000019186 ENSG00000186104 ENSG00000135929 PMC6088103__F4 AD genes selected by cross metrics analysis and their relation with other diseases ENSG00000142192 ENSG00000108691 ENSG00000105329 ENSG00000136869 ENSG00000112715 ENSG00000073756 PMC5922990__F6 Naringenin prevents acute and chronic CCl4-induced liver damage ENSG00000178573 ENSG00000168040 ENSG00000079999 PMC5922990__F7 Naringenin in cancer development ENSG00000138798 ENSG00000177606 ENSG00000123374 ENSG00000171791 ENSG00000100985 ENSG00000146648 PMC4822554__F1 Glucose promotes tumor growth by activating lipid synthesis and uptake upon N-glycosylation of SCAP ENSG00000130164 ENSG00000146648 PMC2778955__F10 Expression of an IKKG Splice Variant Determines IRF3 and Canonical NFKB Pathway Utilization in ssRNA Virus Infection ENSG00000088888 ENSG00000173039 PMC11972266__F2 Isorhamnetin inhibits cholangiocarcinoma proliferation and metastasis via PI3K/AKT signaling pathway ENSG00000177455 ENSG00000103479 ENSG00000157933 ENSG00000002330 ENSG00000179091 ENSG00000186716 ENSG00000104894 PMC7997989__F9 TDP-43 and PINK1 mediate CHCHD10S59L mutation–induced defects in Drosophila and in vitro ENSG00000273607 ENSG00000158828 ENSG00000147894 PMC3427417__F7 Nicotine-induced A7nAChR/JAK2 pathway in cooperation with nicotine-mediated ERK1/2 activation potentiates STAT3 activation in PC cells ENSG00000173599 ENSG00000168610 ENSG00000145113 ENSG00000062485 PMC5890734__F1 Overview of Ethylene Biosynthesis and Signaling Pathways in Arabidopsis and Environmental Factors That Modulate Ethylene Signaling ENSG00000221818 PMC9547606__F2 Platelets, Macrophages, and Thromboinflammation in Chagas Disease ENSG00000173599 PMC3085710__F4 KEGG Pathway Map () ENSG00000181104 ENSG00000203710 ENSG00000244731 ENSG00000115718 ENSG00000122194 ENSG00000178726 ENSG00000185010 ENSG00000104368 ENSG00000236625 ENSG00000184500 ENSG00000180210 ENSG00000126218 ENSG00000101981 ENSG00000117525 ENSG00000011422 ENSG00000164344 ENSG00000039537 ENSG00000009724 ENSG00000003436 ENSG00000113600 ENSG00000291559 ENSG00000088926 ENSG00000166278 ENSG00000117322 ENSG00000117601 ENSG00000057593 ENSG00000175899 ENSG00000080618 ENSG00000198734 ENSG00000276838 PMC5997273__F1 Road to Crohn’s disease ENSG00000144895 ENSG00000172936 PMC8636012__F1 Importance of Cellular Metabolic Pathways in Pathogenesis and Selective Treatments of Hematological Malignancies ENSG00000169710 ENSG00000115419 ENSG00000159399 PMC4901515__F1 Cilia-mediated signaling pathways whose proper regulation is dependent on the proteasome and the structure of the proteasome ENSG00000134982 ENSG00000134853 ENSG00000164690 ENSG00000128602 PMC11789227__F3 Therapeutic potential of SOX family transcription factors in osteoarthritis ENSG00000198879 ENSG00000131914 ENSG00000163435 ENSG00000187531 ENSG00000107562 ENSG00000125398 ENSG00000168036 ENSG00000108671 ENSG00000096717 ENSG00000121966 PMC155638__F3 Hypoxic activation of apoptosis pathways ENSG00000002330 ENSG00000120868 PMC155638__F1 MAP kinase signalling pathways ENSG00000157557 ENSG00000070831 ENSG00000163914 ENSG00000081189 PMC3993959__F3 Bioinformatic analyses expose alterations in nucleic acid binding and regulatory proteins ENSG00000205323 ENSG00000085872 ENSG00000288411 ENSG00000086589 PMC8871586__F8 Gene Ontology Groups and Signaling Pathways Regulating the Process of Avian Satellite Cell Differentiation ENSG00000101605 ENSG00000143549 ENSG00000136842 ENSG00000077522 ENSG00000130402 ENSG00000155657 ENSG00000140416 ENSG00000198947 PMC7539288__F6 NAD+ deficits in aging-associated dysfunction and cancer ENSG00000105835 ENSG00000150907 PMC9362381__F4 Thrombosis leading to acute abdomen in corona virus disease- 19:A case series ENSG00000110799 ENSG00000130234 ENSG00000162692 PMC10744232__F3 Pomegranate (Punica granatum L.) and Its Rich Ellagitannins as Potential Inhibitors in Ulcerative Colitis ENSG00000198793 ENSG00000168610 ENSG00000115594 PMC7539288__F1 NAD+ metabolism and its physiological function ENSG00000105835 ENSG00000278488 ENSG00000112992 PMC7539288__F2 Subcellular equilibrium of NAD+ ENSG00000151376 ENSG00000065833 ENSG00000157064 ENSG00000173614 ENSG00000112992 ENSG00000008130 ENSG00000105227 PMC7867045__F3 Genetic alterations leading to HIF activation in GB ENSG00000138798 ENSG00000146648 PMC3043094__F3 Identifying Consensus Disease Pathways in Parkinson's Disease Using an Integrative Systems Biology Approach ENSG00000182533 ENSG00000186716 PMC7089929__F4 Distribution of differentially expressed genes (DEGs) of the cell cycle pathway (dre04110) in diploid and tetraploid states in vitro and in vivo ENSG00000145604 ENSG00000132646 ENSG00000123374 ENSG00000164754 ENSG00000277273 ENSG00000166851 ENSG00000276876 PMC3043094__F4 Identifying Consensus Disease Pathways in Parkinson's Disease Using an Integrative Systems Biology Approach ENSG00000087095 ENSG00000163930 ENSG00000170458 ENSG00000177606 ENSG00000198517 ENSG00000127191 ENSG00000081189 PMC3043094__F2 Identifying Consensus Disease Pathways in Parkinson's Disease Using an Integrative Systems Biology Approach ENSG00000168036 ENSG00000080166 ENSG00000107165 PMC5663837__F4 ErbB signaling pathway and its circRNA-related genes ENSG00000002330 ENSG00000182446 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000159461 ENSG00000099942 ENSG00000135506 ENSG00000198162 ENSG00000169291 ENSG00000113558 ENSG00000132388 ENSG00000130939 ENSG00000157764 ENSG00000113070 ENSG00000158458 ENSG00000184787 ENSG00000169752 ENSG00000291983 ENSG00000128272 ENSG00000100387 ENSG00000163235 ENSG00000177606 ENSG00000143322 ENSG00000135018 ENSG00000146648 ENSG00000178568 PMC3135646__F1 P53 pathway in development, cancer, and reprogramming ENSG00000149311 ENSG00000175054 ENSG00000168283 ENSG00000136997 PMC11516169__F9 CsEVs in promoting malignant proliferation and metastasis of CCA cells ENSG00000112576 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC3049961__F8 Analysis of phosphotyrosine signaling in glioblastoma identifies STAT5 as a novel downstream target of ΔEGFR ENSG00000152661 ENSG00000111859 ENSG00000291971 ENSG00000169439 ENSG00000250506 ENSG00000277273 ENSG00000089159 ENSG00000107338 ENSG00000144283 ENSG00000173757 ENSG00000124181 ENSG00000146648 ENSG00000136205 PMC7672634__F1 Ingenuity pathway analysis of FGF/FGFR pathway suppressed by cordycepin in MA-10 cells ENSG00000162889 ENSG00000019991 ENSG00000168610 PMC9249506__F10 Inhibition of PLK3 Attenuates Tubular Epithelial Cell Apoptosis after Renal Ischemia–Reperfusion Injury by Blocking the ATM/P53-Mediated DNA Damage Response ENSG00000149311 ENSG00000173846 ENSG00000171791 PMC5133671__F8 Simplified model for how AhR mediates the RANK/c-Fos signaling axis of osteoclast differentiation and bone resorption ENSG00000131196 ENSG00000106546 PMC1383550__F2 Two branches of the class I PI3K pathway ENSG00000070831 PMC9297732__F6 Multi-pronged anti-cancer activity of PI3KD inhibition in cancer ENSG00000186716 ENSG00000171791 PMC7710361__F5 Landscapes of bacterial and metabolic signatures and their interaction in major depressive disorders PMC8633417__F2 Dietary Patterns and Associated Microbiome Changes that Promote Oncogenesis ENSG00000136997 ENSG00000168036 ENSG00000172936 ENSG00000136869 ENSG00000128602 PMC8633417__F1 Dietary Patterns and Associated Microbiome Changes that Promote Oncogenesis ENSG00000150782 ENSG00000168610 ENSG00000293532 ENSG00000007171 PMC11869728__F1 Canonical TGFB/SMAD and Wnt/Beta-catenin signaling pathway ENSG00000137834 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9438347__F14 Plant-based medicinal food on postoperative recurrence and lung metastasis of gastric cancer regulated by Wnt/Beta-catenin-EMT signaling pathway and VEGF-C/D-VEGFR-3 cascade in a mouse model ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000100744 PMC1779520__F3 Signaling pathways activated by serum and GF treatments ENSG00000136158 ENSG00000120833 ENSG00000151490 ENSG00000154217 ENSG00000170027 ENSG00000138166 ENSG00000171150 ENSG00000291971 ENSG00000099860 ENSG00000168610 ENSG00000187678 PMC5705586__F3 Fibroblast Growth Factor 2 as an Antifibrotic: Antagonism of Myofibroblast Differentiation and Suppression of Pro-Fibrotic Gene Expression PMC4959856__F6 VNN1 expression and function can be regulated by Ox-LDL to promote atherosclerosis ENSG00000141458 ENSG00000160179 ENSG00000162692 ENSG00000112299 PMC2804818__F5 A summary of the ligand-mediated control of TRP53 expression via the PI3 kinase/AKT/MDM2 pathway ENSG00000124102 PMC7567487__F2 Mammarenavirus life cycle ENSG00000135838 ENSG00000072274 ENSG00000135404 ENSG00000118257 PMC8886606__F2 Concanavalin A-induced autoimmune hepatitis model in mice: Mechanisms and future outlook ENSG00000170458 ENSG00000102871 ENSG00000172936 ENSG00000150455 ENSG00000105639 ENSG00000175104 ENSG00000127191 ENSG00000010671 PMC2990745__F1 Examples of pathways shared by a signature hub from the Wang dataset and a signature hub from the Desmedt dataset ENSG00000110700 ENSG00000280831 ENSG00000265681 ENSG00000182774 ENSG00000170458 ENSG00000109475 ENSG00000213741 ENSG00000161970 ENSG00000171863 ENSG00000026103 PMC8886606__F1 Concanavalin A-induced autoimmune hepatitis model in mice: Mechanisms and future outlook ENSG00000186810 ENSG00000125538 ENSG00000026103 PMC6121189__F6 Prolactin-driven signaling pathways via the short or long prolactin receptors PMC4711587__F3 De Novo Assembly and Characterization of Early Embryonic Transcriptome ENSG00000043355 ENSG00000087095 ENSG00000180447 ENSG00000095739 ENSG00000167941 PMC8150799__F4 Physiological and Pathological Inflammation Induced by Antibodies and Pentraxins ENSG00000183735 ENSG00000125538 ENSG00000132693 PMC7784492__F3 Pathways affected by mutations ENSG00000160867 ENSG00000135446 ENSG00000123374 ENSG00000168610 ENSG00000196712 PMC3264379__F9 Proposed model for regulation of HCV replication mediated by the Ras/Raf/MEK pathway ENSG00000213928 ENSG00000105397 PMC8804383__F7 Curcumin Ameliorates Cardiac Fibrosis by Regulating Macrophage-Fibroblast Crosstalk via IL18-P-SMAD2/3 Signaling Pathway Inhibition ENSG00000125538 PMC6230569__F4 miRNAs modulating dendrite morphogenesis converge ENSG00000106683 ENSG00000101752 PMC2587303__F1 mTOR inhibition as a Therapeutic Strategy in the Management of Urologic Malignancies ENSG00000169047 ENSG00000198793 ENSG00000163914 ENSG00000164327 PMC4383161__F2 Integration of the 3 major pathways that regulate skeletal muscle mass ENSG00000132646 ENSG00000198793 PMC5995256__F5 Pathways altered in brain metastases compared to primary NSCLC ENSG00000002330 ENSG00000105401 ENSG00000168036 PMC11047590__F1 Redox systems involved in microglia ENSG00000162711 ENSG00000151012 ENSG00000100387 ENSG00000167468 ENSG00000168036 ENSG00000265972 ENSG00000105227 ENSG00000079999 PMC11047590__F2 Redox regulation of immunometabolism in the polarization of microglia in DR ENSG00000182511 ENSG00000198793 ENSG00000136869 PMC3966620__F1 Cl− channels in cardiac myocytes ENSG00000016490 ENSG00000001626 PMC3778395__F1 Plant tetrapyrrole biosynthetic pathway ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000256269 ENSG00000188690 ENSG00000127948 ENSG00000105227 PMC11506738__F3 Key pathways of COVID-19 vaccine-induced adverse immune reactions ENSG00000183695 ENSG00000134982 PMC11506738__F4 Various mechanisms of adverse immune activation by COVID-19 vaccines ENSG00000239732 ENSG00000164430 ENSG00000111537 ENSG00000113520 ENSG00000163737 ENSG00000113525 ENSG00000276561 PMC5679221__F2 Glia unglued: How signals from the extracellular matrix regulate the development of myelinating glia ENSG00000070831 ENSG00000010810 ENSG00000198793 PMC5679221__F1 Glia unglued: How signals from the extracellular matrix regulate the development of myelinating glia ENSG00000070831 ENSG00000010810 PMC6566438__F7 Some of the signaling pathways involved in the differentiation of ADSCs into IPCs ENSG00000169047 ENSG00000168610 PMC8355044__F1 Functional outside-in signaling network of proteoglycans and matrix molecules regulating autophagy ENSG00000198793 ENSG00000026508 ENSG00000136869 ENSG00000112715 ENSG00000146648 ENSG00000198300 PMC6875034__F6 STRING analysis of integrin signaling pathways and response to wound healing pathways ENSG00000182718 ENSG00000135218 ENSG00000143546 ENSG00000259207 ENSG00000100345 ENSG00000010278 ENSG00000137509 ENSG00000130402 ENSG00000138119 ENSG00000135124 ENSG00000078098 ENSG00000146648 ENSG00000024422 ENSG00000136068 ENSG00000101608 ENSG00000135919 PMC9556788__F7 Chronic heat stress induces the disorder of gut transport and immune function associated with endoplasmic reticulum stress in growing pigs ENSG00000136100 ENSG00000048462 ENSG00000117118 ENSG00000171863 ENSG00000163541 ENSG00000244731 ENSG00000143858 ENSG00000108561 ENSG00000167881 ENSG00000173369 ENSG00000004478 ENSG00000116161 ENSG00000118322 ENSG00000067704 ENSG00000156587 ENSG00000180008 ENSG00000024422 ENSG00000054523 ENSG00000196511 ENSG00000131473 ENSG00000137145 ENSG00000132109 ENSG00000009724 ENSG00000113600 ENSG00000106367 ENSG00000100994 ENSG00000156976 ENSG00000166278 ENSG00000105402 ENSG00000113384 ENSG00000101310 ENSG00000173372 ENSG00000259823 ENSG00000181036 ENSG00000153048 ENSG00000197879 ENSG00000139116 ENSG00000123838 ENSG00000115361 ENSG00000182271 ENSG00000166986 ENSG00000127948 ENSG00000141367 PMC8616071__F1 Canonical and Non-Canonical Roles of PFKFB3 in Brain Tumors ENSG00000012061 ENSG00000149311 ENSG00000012048 ENSG00000112576 ENSG00000065833 ENSG00000135446 ENSG00000171848 ENSG00000051180 ENSG00000105810 PMC9095352__F7 Inhibitory Effect of Ursolic Acid on Proliferation and Migration of Renal Carcinoma Cells and Its Mechanism ENSG00000164690 ENSG00000128602 PMC5070718__F1 Levels of miR-146a and miR-146b are regulated by innate immune signaling ENSG00000136869 ENSG00000175104 ENSG00000168610 ENSG00000184216 ENSG00000115009 ENSG00000100065 ENSG00000164342 PMC5378112__F1 Genetic model of the insect melanin biosynthesis pathway () PMC6820234__F1 Heme biosynthetic pathway and experimental porphyria models ENSG00000110711 ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000256269 ENSG00000168036 ENSG00000188690 ENSG00000115657 ENSG00000005381 ENSG00000118777 PMC4380839__F1 ROCK and Rho ENSG00000198670 PMC3998841__F2 Inflammatory cytokine-associated idiosyncratic drug hepatotoxicity as a “network toxicity” ENSG00000138794 PMC3767467__F4 Proposed model of TRP47 effector function in E ENSG00000010810 ENSG00000180628 PMC8657105__F5 Histopathological and Molecular Profiling of Clear Cell Sarcoma and Correlation with Response to Crizotinib: An Exploratory Study Related to EORTC 90101 “CREATE” Trial ENSG00000095002 PMC7872968__F7 Phagosome maturation pathway, (B) RIP1 and ECSIT signaling pathway, (C) arachidonic acid metabolism pathway, and (D) cytotoxic T cells signaling pathway using CD226 and PVR axis ENSG00000102189 ENSG00000213928 ENSG00000130159 ENSG00000168040 ENSG00000175104 ENSG00000127191 PMC7872968__F8 RIG-I signaling pathway ENSG00000183735 ENSG00000088888 ENSG00000102871 ENSG00000160703 ENSG00000131323 ENSG00000168040 ENSG00000175104 ENSG00000127191 PMC8716783__F2 Long Noncoding RNA H19: A Novel Therapeutic Target Emerging in Oncology Via Regulating Oncogenic Signaling Pathways ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000168040 PMC7872968__F5 HIF-1 signaling pathway and (B) relaxin signaling pathway in lungs ENSG00000087245 ENSG00000198793 ENSG00000100985 ENSG00000168610 PMC7872968__F6 IL-17 signaling pathway ENSG00000144118 ENSG00000165527 ENSG00000175104 ENSG00000177663 ENSG00000163702 PMC7188829__F5 DEGs enriched in TNF (A), PI3K-AKT (B) signaling pathway during A ENSG00000177455 ENSG00000002330 ENSG00000102871 ENSG00000186716 ENSG00000168040 ENSG00000197601 PMC4239617__F10 Proposed mechanism/model for the rationale of treatment with a combination regimen of GCs and IFNA in HBV-infected cell ENSG00000151224 ENSG00000115415 ENSG00000145321 PMC4222351__F4 P-21 activated kinase (PAK)1 in canonical and non-canonical NFKB signalling ENSG00000104856 ENSG00000070831 ENSG00000149269 ENSG00000173039 ENSG00000136869 PMC8470495__F1 Promising Biomarkers of Radiation-Induced Lung Injury: A Review ENSG00000198793 ENSG00000163453 ENSG00000168036 ENSG00000189403 PMC6955834__F4 Intermittent fasting‐mediated pathways that induce adult hippocampal neurogenesis ENSG00000148400 ENSG00000273529 PMC10297110__F5 The effects of inhibiting TGFB signaling pathways on hCECs in vitro ENSG00000122882 ENSG00000198793 ENSG00000163914 PMC6210224__F11 IFN-λ3 rescued the RIG-I signaling pathway ENSG00000088888 ENSG00000115415 ENSG00000135114 ENSG00000291876 ENSG00000107201 ENSG00000121060 ENSG00000276561 PMC6199328__F8 TEdeff-induced immunotherapy resistance ENSG00000115415 ENSG00000168040 ENSG00000168610 ENSG00000064012 PMC8818883__F4 Transcriptome Analysis of Peripheral Blood Mononuclear Cells in Pulmonary Sarcoidosis ENSG00000078747 ENSG00000168040 ENSG00000127191 PMC3745214__F1 Targeting TGFB signaling in cancer ENSG00000137834 ENSG00000163914 ENSG00000175104 PMC8818883__F5 Transcriptome Analysis of Peripheral Blood Mononuclear Cells in Pulmonary Sarcoidosis ENSG00000111837 ENSG00000172005 ENSG00000198576 ENSG00000105656 ENSG00000023697 PMC8770568__F1 Therapeutic targets identified in clinical and pre-clinical studies for ESR1 mutant breast cancer ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000140443 PMC8818883__F6 Transcriptome Analysis of Peripheral Blood Mononuclear Cells in Pulmonary Sarcoidosis ENSG00000144410 PMC8818883__F7 Transcriptome Analysis of Peripheral Blood Mononuclear Cells in Pulmonary Sarcoidosis ENSG00000135218 ENSG00000170458 ENSG00000079950 ENSG00000136869 ENSG00000005381 PMC3745214__F4 Targeting TGFB signaling in cancer PMC8764032__F4 Proximity ligation strategy for the genomic reconstruction of microbial communities associated with the ectoparasite Caligus rogercresseyi ENSG00000137992 ENSG00000078070 ENSG00000151498 ENSG00000122971 ENSG00000128928 ENSG00000091140 ENSG00000117305 PMC314152__F7 LMP1-induced canonical and noncanonical NFKB activation ENSG00000104856 ENSG00000162924 ENSG00000127191 ENSG00000184216 ENSG00000121966 PMC5697452__F6 Mechanism by which MMP-9 regulates formation of focal adhesion junctions ENSG00000291971 ENSG00000026508 ENSG00000146648 PMC11640812__F2 Crosstalk relationships between signaling pathways ENSG00000198793 PMC11523861__F1 Dietary Sources of Tryptophan and Main Pathways of Tryptophan Degradation (a) Tryptophan, an essential amino acid, is commonly acquired from dietary sources such as turkey, eggs, cheese, tofu, seeds, and fish ENSG00000162882 ENSG00000183077 PMC11523861__F2 Tryptophan Sample Collection, Detection Methods, and Biological Functions Samples for tryptophan detection are typically obtained from blood specimens, cancer tissues, and cancer cell lines ENSG00000186716 PMC6196929__F1 Possible signaling mechanisms of SERM actions in neurocognition and neuroprotection ENSG00000138798 ENSG00000168036 PMC2896874__F11 Schematic overview of MAPK-regulated processes that are thought to couple light to the SCN clock during the early night ENSG00000179094 PMC9677642__F7 Identification of crucial genes and metabolites regulating the eggshell brownness in chicken ENSG00000144659 ENSG00000135776 ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000256269 ENSG00000188690 ENSG00000118777 PMC9530249__F2 NFKB and its crosstalk with endoplasmic reticulum stress in atherosclerosis ENSG00000162711 ENSG00000135218 ENSG00000137033 ENSG00000136869 PMC9530249__F3 NFKB and its crosstalk with endoplasmic reticulum stress in atherosclerosis ENSG00000162711 ENSG00000088888 ENSG00000128272 ENSG00000144895 ENSG00000204977 ENSG00000125538 ENSG00000086991 ENSG00000132478 ENSG00000100219 ENSG00000127191 ENSG00000106100 PMC3855043__F5 IPA pathways of ChIP-Seq-based NSRF target genes in ESC PMC6438767__F7 Cannabinoid-1 Receptor Antagonism Improves Glycemic Control and Increases Energy Expenditure via Sirt1/mTORC2 and AMPK Signaling ENSG00000150907 ENSG00000164327 ENSG00000096717 PMC6600375__F6 TGFB mediates metastasis ENSG00000167772 ENSG00000154485 ENSG00000166670 PMC4034110__F1 Mitochondrial and metabolic checkpoints of T-cell activation and apoptosis signals ENSG00000197943 ENSG00000084774 PMC6932957__F7 Hypothesized pathway of mitochondrial apoptosis activation induced by HEV infection ENSG00000146469 ENSG00000125538 ENSG00000086991 PMC5620223__F7 EGFR signaling promotes inflammation and cancer stem-like activity in inflammatory breast cancer ENSG00000138798 ENSG00000156574 ENSG00000146648 PMC4134689__F2 Therapeutic strategies to target mutant NRAS: Direct targeting strategies include inhibition of RAS transcription by RNA interference and blockade of posttranslational modification by farnesyltransferase inhibitors ENSG00000135446 ENSG00000198793 PMC6600375__F1 TGFB/SMAD and non-SMAD signaling ENSG00000070831 ENSG00000198742 ENSG00000198793 ENSG00000076604 PMC11523861__F3 Molecular mechanisms and therapeutic significance of Tryptophan Metabolism and signaling in cancer ENSG00000103257 ENSG00000183077 ENSG00000106546 PMC6600375__F2 TGF-Beta-induced growth inhibition and apoptosis ENSG00000100290 ENSG00000175104 PMC11523861__F5 Molecular Mechanisms of Tryptophan Metabolism in Digestive System Cancers (a) Tryptophan metabolism plays dual roles in digestive system cancers, promoting or suppressing tumor growth ENSG00000111537 ENSG00000136997 ENSG00000103257 ENSG00000005381 ENSG00000117399 ENSG00000106546 PMC9694461__F1 New Therapeutic Trend: Natural Medicine for Ameliorating Ischemic Stroke via PI3K/Akt Signaling Pathway ENSG00000198793 ENSG00000102934 ENSG00000038002 ENSG00000168040 ENSG00000026103 PMC9305908__F1 17Beta-Estradiol Concentration and Direct B2-Adrenoceptor Inhibition Determine Estrogen-Mediated Reversal of Adrenergic Immunosuppression PMC6102727__F7 Schematic overview of LATS1/YAP/RHAMM pathway and the regulatory effects of LATS1 in the LATS1/YAP/RHAMM pathway ENSG00000198793 ENSG00000131023 PMC6869463__F6 Schematic showing the role of CNPase/Notch signalling pathway in modulating EMT and fibrosis PMC2835842__F1 HSV-1-mediated antagonism of TLR-dependent, anti-viral pathways ENSG00000239732 ENSG00000172936 ENSG00000135828 ENSG00000175104 ENSG00000164342 PMC5226503__F4 Gene network analysis reveals a novel 22-gene signature of carbon metabolism in hepatocellular carcinoma ENSG00000284320 ENSG00000197713 ENSG00000175198 ENSG00000136872 ENSG00000159399 PMC9696821__F6 Network Pharmacology of Ginseng (Part III): Antitumor Potential of a Fixed Combination of Red Ginseng and Red Sage as Determined by Transcriptomics PMC5374583__F7 Survival and proliferative effects of AOF extract on RSC96 Schwann cell ENSG00000002330 ENSG00000140443 PMC2693384__F2 Regulation of Vascular Permeability by Sphingosine 1-Phosphate ENSG00000134982 ENSG00000149269 ENSG00000084774 PMC3038250__F4 PI3K/Akt and RAS/BRaf/MEK pathways are frequently altered in melanoma ENSG00000117020 ENSG00000157764 PMC7258707__F7 Potentiating immune response by activating TLR signaling pathways.With the exception of TLR3, all TLRs activate MyD88 dependent pathway which leads to NFKB mediated proinflammatory cytokine upregulation ENSG00000183735 ENSG00000239732 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC9658955__F8 LMNA Reduced Acquired Resistance to Erlotinib in NSCLC by Reversing the Epithelial–Mesenchymal Transition via the FGFR/MAPK/c-fos Signaling Pathway ENSG00000138798 ENSG00000146648 PMC8540886__F2 Nature vs. Nurture: The Two Opposing Behaviors of Cytotoxic T Lymphocytes in the Tumor Microenvironment ENSG00000089692 ENSG00000134982 ENSG00000180644 ENSG00000122862 ENSG00000026103 PMC9179421__F1 Cancer-Induced Metabolic Rewiring of Tumor Endothelial Cells ENSG00000135605 ENSG00000115419 ENSG00000159399 ENSG00000026103 PMC12152662__F1 Regulation mechanism of PD-L1 in cellMultiple transcription factors directly modulate PD-L1 expression through distinct mechanisms ENSG00000019991 ENSG00000141867 ENSG00000111537 ENSG00000157764 ENSG00000115415 ENSG00000138798 ENSG00000198793 ENSG00000136997 ENSG00000125347 ENSG00000168610 ENSG00000146648 PMC12152662__F2 PD-L1 in the ALK oncogenic signaling pathway in NSCLCThe EML4-ALK fusion protein enhances PD-L1 expression by activating downstream signaling pathways, including ERK, AKT, STAT3, and HIF-1A (24) ENSG00000198793 ENSG00000162772 PMC6035094__F3 An overview of the cannabinoid type 2 (CB2) receptor system and its therapeutic potential ENSG00000174125 ENSG00000243414 ENSG00000183735 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC9572342__F10 Fermentation Extract of Naringenin Increases the Expression of Estrogenic Receptor B and Modulates Genes Related to the p53 Signalling Pathway, miR-200c and miR-141 in Human Colon Cancer Cells Exposed to BPA ENSG00000078900 ENSG00000177519 ENSG00000120868 PMC3737462__F2 Accumulation of monocytes/macrophages in adipose tissue and liver, and activation in the tissues ENSG00000125538 ENSG00000136869 ENSG00000136826 PMC3442742__F1 NGF signaling pathways in mediating neurotrophic and nociceptor effects.Notes: NGF signals through the high-affinity TrkA and low p75NTR receptors ENSG00000196689 PMC2435278__F2 The Aedes aegypti Toll Pathway Controls Dengue Virus Infection ENSG00000166402 ENSG00000172936 ENSG00000168040 PMC6047740__F2 Connections of Wnt pathway components with cell cycle and centrosome: side effects or a hidden logic? ENSG00000169071 ENSG00000100592 ENSG00000185483 ENSG00000168036 PMC3735683__F3 From Genetics of Inflammatory Bowel Disease Towards Mechanistic Insights ENSG00000140279 ENSG00000116701 ENSG00000100365 PMC6047740__F5 Connections of Wnt pathway components with cell cycle and centrosome: side effects or a hidden logic? ENSG00000117650 ENSG00000134982 ENSG00000168036 ENSG00000110274 ENSG00000166851 PMC9462662__F2 Relationship of alpha-synuclein to mitochondrial dynamics and quality control ENSG00000123240 ENSG00000158828 ENSG00000099940 PMC5644195__F13 Agents that affect the Hippo pathway (Nat Rev Cancer ENSG00000038382 ENSG00000126016 ENSG00000134982 ENSG00000163914 ENSG00000100697 ENSG00000150457 ENSG00000131023 PMC6722120__F4 BC subtype-specific EV protein kinase networks ENSG00000104365 ENSG00000142627 ENSG00000090402 ENSG00000160867 ENSG00000198793 ENSG00000130669 PMC6682198__F8 Schematic mechanism of apoptosis in ovarian cancer and some current targeted molecular therapeutic approaches ENSG00000285109 ENSG00000198793 ENSG00000026103 ENSG00000276068 PMC9116921__F2 Ongoing Clinical Trials in Aging-Related Tissue Fibrosis and New Findings Related to AhR Pathways ENSG00000168036 ENSG00000096717 ENSG00000142082 ENSG00000106546 PMC4457513__F2 Reelin-Disabled-1 signaling in neuronal migration: Splicing takes the stage ENSG00000106683 ENSG00000070831 ENSG00000170558 ENSG00000166266 ENSG00000173406 PMC6193731__F3 ROS accumulation induced by fungicidal drugs PMC8792817__F1 Metabolism and Health Impacts of Dietary Sugars ENSG00000138030 ENSG00000093217 PMC3524319__F6 Construction of the regulatory networks associated with the selected genes using IPA® database ENSG00000135148 ENSG00000183486 ENSG00000150337 ENSG00000121807 ENSG00000068079 ENSG00000095794 ENSG00000026103 ENSG00000189067 ENSG00000117228 ENSG00000101160 ENSG00000147168 ENSG00000163220 ENSG00000140968 ENSG00000196954 ENSG00000173039 ENSG00000137193 ENSG00000185745 ENSG00000110324 ENSG00000043462 ENSG00000205220 ENSG00000125347 ENSG00000276561 ENSG00000169245 ENSG00000186810 ENSG00000108691 ENSG00000111537 ENSG00000115956 ENSG00000164136 ENSG00000104325 PMC3138766__F6 JAK2 V617F-Dependent Upregulation of PU.1 Expression in the Peripheral Blood of Myeloproliferative Neoplasm Patients ENSG00000173757 ENSG00000168610 PMC5154753__F2 Pathways activated following binding of the TSLP cytokine to its receptor complex ENSG00000145777 PMC1774275__F5 Mitogenic signals are transduced by Ras which inhibits the retinoblastoma (Rb) protein allowing E2F and Myc to promote cell cycle progression ENSG00000002330 ENSG00000136997 ENSG00000026103 PMC1774275__F4 The chromosomal instability (CIN) pathway (see text for details) ENSG00000138795 ENSG00000134982 PMC1774275__F1 Simplified diagram of the Wnt/APC pathway ENSG00000134982 ENSG00000168036 PMC6240956__F3 Foamy phagocyte polarization follows a triphasic pattern ENSG00000111537 ENSG00000125538 ENSG00000118520 PMC4612627__F3 Simplified model of a cell signaling process highlighting the flow from signals generated externally by epidermal growth factor (EGF) to the activation or repression of transcription ENSG00000138798 ENSG00000136997 ENSG00000146648 PMC1774275__F2 Intrinsic, or mitochondrial, pathway (after Danial and Korsmeyer) ENSG00000002330 PMC1375233__F5 Two signaling pathways of TLR in myeloid DCs ENSG00000170458 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC6775198__F1 Role of Wnt Proteins in T cells ENSG00000049768 PMC1375233__F2 Association between human TLRs and adaptors determine each TLR-specific signaling pathway ENSG00000239732 ENSG00000187554 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC3978635__F1 mTOR pathway and actions ENSG00000198793 PMC6775198__F2 Immune exclusion through the Wnt/beta-catenin pathway ENSG00000125538 ENSG00000168036 ENSG00000049768 ENSG00000277943 PMC3978635__F2 mTOR-dependent pathways and inhibitors ENSG00000198793 PMC4547497__F2 Signaling pathways associated with CLRs on dendritic cells ENSG00000187796 PMC2659592__F7 Lysophosphatidic Acid Induces Interleukin-13 (IL-13) Receptor A2 Expression and Inhibits IL-13 Signaling in Primary Human Bronchial Epithelial Cells ENSG00000123496 ENSG00000173599 ENSG00000198670 ENSG00000131724 PMC6775198__F3 Effect of WNT signaling on cancer immunosurveillance ENSG00000123685 ENSG00000049768 ENSG00000277943 PMC5857409__F4 Proposed potential therapeutic targets in Erythroleukemia ENSG00000166869 ENSG00000187266 PMC2651172__F7 Possible site for alcohol-induced inhibition of muscle protein synthesis ENSG00000198793 PMC8457986__F3 Positive Role and Mechanism of Herbal Medicine in Parkinson's Disease ENSG00000162711 ENSG00000128272 ENSG00000002330 ENSG00000079999 PMC4048572__F8 Exercise-Induced Skeletal Muscle Remodeling and Metabolic Adaptation: Redox Signaling and Role of Autophagy ENSG00000177169 ENSG00000196591 ENSG00000096717 ENSG00000145782 ENSG00000057663 PMC8286568__F5 Bacterial alginate metabolism: an important pathway for bioconversion of brown algae ENSG00000142192 ENSG00000197429 PMC7442787__F7 Protein phosphatase 4 promotes Hedgehog signaling through dephosphorylation of Suppressor of fused ENSG00000198125 ENSG00000163605 PMC7652989__F1 Sphingolipid biosynthetic pathway in plants and the inhibition of this pathway by FB1 ENSG00000118785 PMC4746004__F4 Collateral Lethality: A new therapeutic strategy in oncology ENSG00000197713 PMC4383600__F2 Interplay between multiple factors in the transforming growth factorB (TGFB) signalling pathway and the control of muscle mass ENSG00000170365 ENSG00000157933 ENSG00000095739 PMC2705117__F3 Role of peroxisome-proliferator-activated receptor B/D (PPARB/D) in gastrointestinal tract function and disease ENSG00000167772 ENSG00000134982 PMC4071223__F7 Porphyromonas gingivalis manipulates complement and TLR signaling to uncouple bacterial clearance from inflammation and promote dysbiosis ENSG00000174125 ENSG00000198742 ENSG00000172005 ENSG00000172936 PMC10854888__F1 HSP in biochemical functions of cells ENSG00000002330 ENSG00000126775 ENSG00000136869 ENSG00000166278 PMC9413412__F1 Crosstalk effect between ferrous and other ions metabolism in ferroptosis for therapy of cancer ENSG00000168003 ENSG00000151012 ENSG00000197635 ENSG00000167468 ENSG00000111684 ENSG00000115107 ENSG00000127948 PMC10758458__F2 Advances in the role of microRNAs associated with the PI3K/AKT signaling pathway in lung cancer ENSG00000114770 ENSG00000103222 ENSG00000118777 ENSG00000023839 ENSG00000079999 PMC10758458__F3 Advances in the role of microRNAs associated with the PI3K/AKT signaling pathway in lung cancer ENSG00000081913 ENSG00000150907 ENSG00000040199 ENSG00000283060 ENSG00000048740 PMC9380331__F7 Structure and character analysis of cotton response regulator genes family reveals that GhRR7 responses to draught stress ENSG00000163435 ENSG00000160883 ENSG00000102034 ENSG00000203783 ENSG00000105669 ENSG00000159399 ENSG00000126464 PMC4189230__F1 Process and mechanisms of blood vessel formation ENSG00000291971 ENSG00000134853 PMC3143902__F1 Inhibition of myostatin (MSTN) and activin signalling by the soluble activin type IIB receptor (ActRIB) PMC10758458__F1 Advances in the role of microRNAs associated with the PI3K/AKT signaling pathway in lung cancer ENSG00000002330 ENSG00000198793 ENSG00000146648 PMC6436762__F9 Boolean model of growth signaling, cell cycle and apoptosis predicts the molecular mechanism of aberrant cell cycle progression driven by hyperactive PI3K ENSG00000114346 ENSG00000166851 PMC3964957__F6 Pathway diagram customization is available via the web interface, and lets the user control many aspects of the pathway diagram ENSG00000115718 PMC11029991__F7 Bioinformatics-based discovery of biomarkers and immunoinflammatory targets in children with cerebral palsy: An observational study ENSG00000213928 ENSG00000281324 ENSG00000162337 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000131095 ENSG00000167965 ENSG00000105639 ENSG00000145604 ENSG00000168003 ENSG00000105397 ENSG00000163914 ENSG00000106070 ENSG00000176641 PMC5918238__F3 Non-bilayer phospholipids in mitochondrial structure and function ENSG00000087157 ENSG00000146005 ENSG00000184207 PMC6362586__F4 Associative gene network describing interactions between three central genes/proteins of the extrinsic apoptotic signaling pathway biological process ENSG00000100234 ENSG00000143420 ENSG00000105329 ENSG00000163064 ENSG00000151929 ENSG00000171791 ENSG00000012048 ENSG00000010810 ENSG00000019549 ENSG00000056558 ENSG00000170633 ENSG00000104432 ENSG00000026103 PMC6436762__F1 Boolean model of growth signaling, cell cycle and apoptosis predicts the molecular mechanism of aberrant cell cycle progression driven by hyperactive PI3K ENSG00000171105 ENSG00000002330 ENSG00000169047 PMC8809485__F2 Gaucher Disease: Basic and Translational Science Needs for More Complete Therapy and Management ENSG00000162711 ENSG00000183735 ENSG00000137275 ENSG00000125538 ENSG00000112561 ENSG00000285379 PMC11504183__F1 BMP concentration on fate of ectodermal cells to induce epidermal, placodal, neural crest, and neural derivatives ENSG00000164690 ENSG00000114315 ENSG00000126778 PMC11504183__F2 BMP signalling pathway and modulators during development of pre-placodal ectoderm ENSG00000170365 ENSG00000128791 PMC9199383__F2 Neutrophils in COVID-19: Not Innocent Bystanders ENSG00000162711 ENSG00000213928 ENSG00000080345 ENSG00000142166 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000130234 ENSG00000172936 ENSG00000131323 ENSG00000175104 PMC2950451__F3 Metabolic flux distribution through branching areas of the central metabolism of MG1655 and ECOM4LA cell lines ENSG00000159224 ENSG00000122966 ENSG00000172005 PMC7405837__F8 DEGs in RPE cells of the cholesterol synthesis pathway ENSG00000160752 ENSG00000110921 ENSG00000112972 ENSG00000116133 ENSG00000172893 ENSG00000109929 ENSG00000113161 ENSG00000104549 ENSG00000167508 ENSG00000052802 PMC5876234__F10 Lico A-mediated Nrf2 signaling pathway protects APAP-induced ALF via inhibition of mitochondrial dysfunction and apoptosis ENSG00000142192 ENSG00000178573 ENSG00000023909 ENSG00000079999 PMC3742697__F8 Proposed model of Cr(VI)-induced carcinogenesis ENSG00000198793 ENSG00000168036 PMC7868402__F6 LncRNA H19 regulates the gene pathway of osteogenic differentiation through the lncRNA-miRNA-mRNA network (; ; ; ; ) ENSG00000108840 PMC7405837__F6 DEGs in RPE cells of the sugar metabolizing pathway ENSG00000104812 ENSG00000068976 ENSG00000169299 ENSG00000067177 PMC7405837__F7 DEGs in RPE cells of the glycerophospholipid metabolism pathway ENSG00000102230 ENSG00000169814 ENSG00000163624 ENSG00000153823 ENSG00000174915 ENSG00000076555 ENSG00000185813 ENSG00000188257 ENSG00000173599 ENSG00000291994 ENSG00000158669 ENSG00000134324 ENSG00000198670 ENSG00000111666 ENSG00000160216 ENSG00000177666 ENSG00000186281 ENSG00000134255 ENSG00000101290 PMC7405837__F4 DEGs in RPE cells of ATP-producing pathways ENSG00000110711 ENSG00000163114 ENSG00000067992 ENSG00000073578 ENSG00000100412 ENSG00000005882 ENSG00000166260 ENSG00000105953 ENSG00000101365 PMC7405837__F2 DEGs in RPE cells of the circadian rhythm pathway ENSG00000111046 ENSG00000132326 PMC7868402__F3 Regulatory effect of methylation levels of bone metabolism-related genes on bone formation (; ; ; ; ; ; ; ; ) ENSG00000167941 PMC7868402__F4 Illustration of SIRT1 signaling pathway in bone remodeling (; ; ; ; ; ; ) ENSG00000096717 PMC5391975__F3 Signaling networks activating the canonical RAF-MEK-ERK signaling pathway and that have been involved in SCLC metastasis (see text) ENSG00000019991 ENSG00000107562 ENSG00000121966 PMC4970276__F8 Model deciphers molecular mechanisms by which PRMT5/p44 controls cell growth ENSG00000065361 ENSG00000159388 ENSG00000139278 PMC3679380__F5 Extranuclear and nontranscriptional effects of RA and vitamin A ENSG00000291971 PMC7211317__F8 Schematic model for the ability of RTR-1 to induce cell cycle arrest and apoptosis ENSG00000149311 ENSG00000168610 PMC7564532__F4 Hypothalamus-pituitary-gonad (HPG) axis in vertebrates and related molecular pathways ENSG00000109163 ENSG00000069482 ENSG00000166863 ENSG00000138039 PMC9179555__F4 Reducing PDK1/Akt Activity: An Effective Therapeutic Target in the Treatment of Alzheimer’s Disease ENSG00000198793 PMC2992886__F3 Genes associated with autoimmunity regulate the CD40/NFKB signaling pathway ENSG00000056558 ENSG00000127191 PMC4874354__F8 Glycolysis PMC8176995__F3 Can Some Anticancer Treatments Preserve the Ovarian Reserve? ENSG00000157404 ENSG00000128342 PMC7170511__F16 Models for RHAMM-regulated motogenic signaling in keratinocytes and temporal-spatial coordination of keratinocyte and fibroblast migration in excisional wounds ENSG00000026508 ENSG00000100985 ENSG00000146648 PMC3826850__F1 The Drosophila Toll and Imd pathways ENSG00000177030 ENSG00000162924 ENSG00000168040 PMC2491602__F6 TNFA signaling pathway ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC6895844__F6 Network and pathway analysis of shared networks between AD and T2D ENSG00000143799 ENSG00000029363 ENSG00000100519 ENSG00000265681 ENSG00000187608 ENSG00000134884 ENSG00000124762 ENSG00000095585 ENSG00000012048 ENSG00000182004 ENSG00000066044 ENSG00000136997 ENSG00000143977 ENSG00000187531 ENSG00000142192 ENSG00000154589 ENSG00000170860 ENSG00000170027 ENSG00000135473 ENSG00000106299 ENSG00000185745 ENSG00000111530 ENSG00000104408 ENSG00000281766 ENSG00000118503 ENSG00000162692 ENSG00000146648 ENSG00000178568 ENSG00000112701 ENSG00000101460 ENSG00000100129 ENSG00000110651 ENSG00000168036 ENSG00000101266 ENSG00000134419 ENSG00000071082 ENSG00000122565 ENSG00000124795 ENSG00000108055 ENSG00000156976 ENSG00000143933 ENSG00000168040 ENSG00000086758 ENSG00000141480 ENSG00000034713 ENSG00000074266 ENSG00000115232 ENSG00000096401 ENSG00000139112 PMC6895844__F7 Network and pathway analysis of shared networks between advanced AD and T2D ENSG00000094631 ENSG00000135655 ENSG00000029363 ENSG00000030066 ENSG00000164164 ENSG00000167005 ENSG00000105401 ENSG00000104517 ENSG00000134308 ENSG00000163064 ENSG00000165280 ENSG00000168036 ENSG00000012048 ENSG00000116161 ENSG00000066044 ENSG00000136997 ENSG00000153147 ENSG00000125686 ENSG00000132383 ENSG00000123562 ENSG00000180008 ENSG00000188612 ENSG00000100603 ENSG00000023516 ENSG00000187531 ENSG00000142192 ENSG00000170027 ENSG00000108773 ENSG00000111530 ENSG00000143933 ENSG00000105568 ENSG00000186298 ENSG00000111725 ENSG00000177565 ENSG00000116001 ENSG00000066468 ENSG00000163539 ENSG00000167986 ENSG00000175104 ENSG00000162692 ENSG00000115232 ENSG00000146648 ENSG00000155363 PMC6669704__F1 Prostaglandin biosynthetic pathway ENSG00000166278 ENSG00000124212 PMC5788649__F1 Gene master regulators of papillary and anaplastic thyroid cancers ENSG00000047410 ENSG00000110330 ENSG00000002330 ENSG00000107443 ENSG00000142330 ENSG00000168036 ENSG00000105647 ENSG00000171791 ENSG00000169032 ENSG00000172795 ENSG00000121879 ENSG00000164305 ENSG00000124762 ENSG00000160049 ENSG00000136997 ENSG00000130222 ENSG00000132906 ENSG00000023445 ENSG00000104365 ENSG00000138795 ENSG00000143549 ENSG00000157764 ENSG00000100906 ENSG00000109320 ENSG00000138794 ENSG00000269335 ENSG00000173039 ENSG00000213341 ENSG00000127191 ENSG00000006062 ENSG00000188389 ENSG00000120910 ENSG00000117020 ENSG00000188191 ENSG00000134574 ENSG00000122008 PMC7016469__F6 Cyclooxygenase 2 (COX2) promotes ovarian cancer cell proliferation and invasion via the prostaglandin E2 (PGE2)/ nuclear factor-kappa B (NFKB) signaling pathway ENSG00000087245 ENSG00000125384 ENSG00000100985 ENSG00000168610 PMC4316382__F2A BMolecular Pathways: Novel Approaches for Improved Therapeutic Targeting of Hedgehog Signaling in Cancer Stem Cells ENSG00000114346 ENSG00000166670 ENSG00000128602 PMC1828403__F1 Representation of TLR4-signaling through the MyD88-dependent and MyD88-independent pathways ENSG00000183735 ENSG00000213928 ENSG00000105397 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 ENSG00000142166 PMC4742202__F5 Genome and transcriptome delineation of two major oncogenic pathways governing invasive ductal breast cancer development ENSG00000107485 ENSG00000121879 ENSG00000067955 ENSG00000145113 PMC2947987__F3 Genome of a Pathogenic Rhodococcus: Cooptive Virulence Underpinned by Key Gene Acquisitions ENSG00000104237 ENSG00000137392 ENSG00000285250 PMC11604654__F4 Two signaling pathways that Fish oil and Forskolin involved23–25 ENSG00000171105 ENSG00000130164 ENSG00000130385 PMC12174911__F1 Cross-regulation of ferroptosis and immunogenic cell death in tumor microenvironment ENSG00000167468 ENSG00000189403 ENSG00000005381 PMC12174911__F2 Comprehensive schematic diagram of cross-regulation of ferroptosis and immunogenic cell death ENSG00000151012 ENSG00000115415 PMC2663527__F1 The formation of leukotrienes (LTs) through the 5-lipoxygenase pathway of arachidonic acid metabolism, and the effects of LT inhibitors in different contexts ENSG00000226275 ENSG00000132693 PMC9702548__F7 The effects of HFPGE on the immune response in RAW 264.7 cells ENSG00000169245 ENSG00000175104 PMC8431791__F2 Roles of c-Jun N-Terminal Kinase (JNK) in Infectious Diseases ENSG00000070831 ENSG00000163914 PMC8017335__F2 IL-1 family cytokines regulate NK-cell responses ENSG00000138378 ENSG00000137033 PMC8017335__F3 Type 2 cytokines show diverse effect of NK cells activation ENSG00000138378 ENSG00000168610 PMC3666258__F5 Diagram of norrin as a multifunctional ligand for three receptors/binding proteins PMC7728369__F7 Proposed model illustrating mechanisms of USP39 regulating the proliferation, apoptosis and metastasis of non-small lung cancer cells via regulating the p53 pathway ENSG00000087245 ENSG00000100985 PMC10534927__F3 Could Natural Products Help in the Control of Obesity? Current Insights and Future Perspectives ENSG00000183735 ENSG00000164430 ENSG00000162692 ENSG00000132693 ENSG00000062485 PMC9063567__F1 Altered Cholesterol Homeostasis in Huntington’s Disease ENSG00000138135 ENSG00000116133 ENSG00000172893 ENSG00000036530 ENSG00000135929 PMC4316382__F1A BMolecular Pathways: Novel Approaches for Improved Therapeutic Targeting of Hedgehog Signaling in Cancer Stem Cells ENSG00000180447 ENSG00000144857 ENSG00000128602 PMC9360899__F1 PI3K/AKT signaling pathway in gallbladder carcinoma ENSG00000187908 ENSG00000185591 ENSG00000146648 PMC10871146__F1 Hydrogen maintains an anaerobic environment in the intestine and reduces oxidative damage via selective antioxidant effects ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000005381 PMC4409470__F2 Nutrients, Foods, and Colorectal Cancer Prevention ENSG00000152266 PMC9360899__F2 PI3K/AKT signaling pathway in gallbladder carcinoma ENSG00000026103 PMC5944465__F3 Quantum dots in cytotoxicity ENSG00000162711 ENSG00000172936 ENSG00000120868 ENSG00000175104 PMC2494582__F1 Bypassing vasopressin receptor signaling pathways in nephrogenic diabetes insipidus ENSG00000167580 ENSG00000163914 ENSG00000145321 PMC5209388__F1 Tetrahydrofolate (THF) synthesis, C1 metabolism, and triacylglycerol (TAG) biosynthesis in plant cells ENSG00000228716 ENSG00000173599 ENSG00000171759 PMC6557086__F6 L-Norvaline, a new therapeutic agent against Alzheimer’s disease ENSG00000063176 ENSG00000198793 ENSG00000102003 PMC10649278__F6 Diagram of IL-17 signaling pathway ENSG00000102871 ENSG00000111837 ENSG00000073910 ENSG00000168040 PMC4714141__F4 Pathway of miR-7 in hepatocellular carcinoma ENSG00000128710 ENSG00000198793 ENSG00000146648 PMC9010204__F3 Targeting Oxidative Stress and Endothelial Dysfunction Using Tanshinone IIA for the Treatment of Tissue Inflammation and Fibrosis ENSG00000198793 ENSG00000086991 ENSG00000136869 ENSG00000168610 PMC10623083__F7 CFH knockdown suppresses the stemness of breast cancer cells through regulation of the EPB41L3/MAPK axis ENSG00000082397 ENSG00000119888 ENSG00000272398 ENSG00000026508 ENSG00000000971 ENSG00000188158 PMC5833577__F4 Necroptosis signaling by TNFR1 stimulation via TNF ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC5135332__F6 Reconstruction of purine biosynthetic pathway in C PMC5833577__F3 Signaling pathways of neutrophil necroptosis ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC11839971__F11 circ0066187 promotes pulmonary fibrogenesis through targeting STAT3-mediated metabolism signal pathway ENSG00000197635 ENSG00000123374 ENSG00000168610 PMC2212850__F2 Major signaling pathways for type I IFN gene transcription ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000164342 PMC4714141__F1 Pathway of microRNA-7 in gastric cancer ENSG00000198793 ENSG00000145321 ENSG00000146648 ENSG00000140443 PMC4714141__F3 Pathway of microRNA-7 in colorectal cancer ENSG00000100811 ENSG00000087245 ENSG00000100985 ENSG00000146648 PMC8198407__F3 Interaction between Metformin, Folate and Vitamin B12 and the Potential Impact on Fetal Growth and Long-Term Metabolic Health in Diabetic Pregnancies ENSG00000228716 ENSG00000100714 ENSG00000124275 PMC9312970__F9 Cold Stress Induced Liver Injury of Mice through Activated NLRP3/Caspase-1/GSDMD Pyroptosis Signaling Pathway ENSG00000278718 ENSG00000136869 ENSG00000023909 PMC4791278__F3 Ascidian natural product eusynstyelamide B is a novel topoisomerase II poison that induces DNA damage and growth arrest in prostate and breast cancer cells ENSG00000149311 ENSG00000012048 ENSG00000123975 ENSG00000198625 PMC9535683__F3 Cytoskeletal dysregulation and neurodegenerative disease: Formation, monitoring, and inhibition of cofilin-actin rods ENSG00000070831 ENSG00000118515 ENSG00000010017 ENSG00000084112 PMC8435905__F1 Cerebrospinal Fluid Profile of Cholesterol Metabolites in Parkinson’s Disease and Their Association With Disease State and Clinical Features ENSG00000090402 ENSG00000124575 ENSG00000213658 ENSG00000242110 ENSG00000105516 ENSG00000036530 ENSG00000106603 ENSG00000099377 ENSG00000113790 ENSG00000083807 ENSG00000135929 PMC8435905__F3 Cerebrospinal Fluid Profile of Cholesterol Metabolites in Parkinson’s Disease and Their Association With Disease State and Clinical Features ENSG00000213658 ENSG00000167910 ENSG00000036530 ENSG00000099377 ENSG00000186104 ENSG00000135929 PMC7218026__F6 Schematic presentation of the ACLY PIP2 binding region and the novel Lyn/Src-dependent tyrosine phosphorylation sites ENSG00000131473 ENSG00000291971 PMC4177877__F1 Breast Cancer Stem Cells: Multiple Capacities in Tumor Metastasis ENSG00000168036 ENSG00000128602 PMC4177877__F3 Breast Cancer Stem Cells: Multiple Capacities in Tumor Metastasis ENSG00000198053 PMC7720970__F1 Revisiting Hormonal Control of Vascular Injury and Repair ENSG00000117425 ENSG00000128602 PMC5853294__F1 Metabolic pathways for TAG biosynthesis in green algae ENSG00000173599 ENSG00000026103 PMC8403061__F6 C-Type Natriuretic Peptide Plays an Anti-Inflammatory Role in Rat Epididymitis Induced by UPEC ENSG00000125538 ENSG00000121058 ENSG00000173786 PMC4391155__F5 The PVT1 functions ENSG00000136997 ENSG00000111641 PMC4487016__F2 Amino acid sensing in yeast and mammals at the vacuole or lysosome ENSG00000177058 ENSG00000130147 ENSG00000127580 ENSG00000159899 ENSG00000103091 PMC11898294__F6 Enhanced CTL responses in TNBC via MUC1 mRNA nanovaccine and anti-CTLA-4 therapy ENSG00000163599 ENSG00000214285 PMC4487016__F3 Molecular architecture of the SEA complex ENSG00000100150 ENSG00000127580 ENSG00000159899 ENSG00000103091 PMC11898294__F7 CD8+ T cell-enhancing nanovaccines for cancer treatment ENSG00000276561 PMC7185212__F2 CD8 T cell linear differentiation model ENSG00000111537 ENSG00000134982 ENSG00000156127 ENSG00000150907 ENSG00000020633 ENSG00000126353 PMC6047740__F6 Connections of Wnt pathway components with cell cycle and centrosome: side effects or a hidden logic? ENSG00000134982 ENSG00000129654 ENSG00000143126 ENSG00000163914 ENSG00000156574 ENSG00000143951 ENSG00000008300 ENSG00000092200 ENSG00000164093 PMC11898294__F3 Types and mechanism of nanovaccine adjuvants ENSG00000164430 ENSG00000111537 ENSG00000138755 PMC4531834__F2 Extrinsic cell death pathway is typically triggered by members of the tumor necrosis factor (TNF) family of death receptor ligands, comprising TNF itself, Fas ligand, and TNF-related apoptosis-inducing ligand (TRAIL) ENSG00000102871 ENSG00000157625 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000026103 PMC6888741__F2 DUB family members ENSG00000135655 ENSG00000163930 ENSG00000036672 ENSG00000114374 ENSG00000129204 ENSG00000101557 ENSG00000184979 ENSG00000136878 ENSG00000291527 ENSG00000077254 ENSG00000102226 ENSG00000162607 ENSG00000083799 ENSG00000134588 PMC6888741__F3 Hippo signaling pathway ENSG00000186575 ENSG00000109321 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC6888741__F4 DUBs and their role in Hippo signaling ENSG00000126016 ENSG00000180667 ENSG00000102226 ENSG00000078747 ENSG00000165312 ENSG00000144560 ENSG00000150457 ENSG00000143258 ENSG00000277276 ENSG00000131023 PMC11898294__F1 T-cell activation, immune suppression, and therapeutic strategies in the TME ENSG00000139193 ENSG00000026103 PMC8918930__F10 Chinese Herbal Extracts Exert Neuroprotective Effect in Alzheimer’s Disease Mouse Through the Dopaminergic Synapse/Apoptosis Signaling Pathway ENSG00000162924 PMC5127022__F3 A diagram of host factors involved in MeV inducible stress granule formation and autophagy ENSG00000116001 ENSG00000163435 ENSG00000088888 ENSG00000144895 ENSG00000237693 ENSG00000145782 ENSG00000047932 PMC4844344__F12 SIG5 expression control in the light-signaling pathway regulating the expression of the chloroplast genes psbD and psbA for the photoreaction center II core proteins D1 and D2 in response to light intensity and quality PMC4695848__F1 Functional role of deubiquitinating enzymes in autophagy ENSG00000118369 ENSG00000135655 ENSG00000136878 ENSG00000077254 ENSG00000055483 ENSG00000144118 ENSG00000135093 PMC6288913__F1 HCV life cycle and involved Rab proteins ENSG00000118508 ENSG00000174903 ENSG00000142627 ENSG00000130164 ENSG00000112210 ENSG00000138798 ENSG00000103769 ENSG00000110651 ENSG00000099246 ENSG00000146648 ENSG00000166128 PMC8649520__F1 Bioinformatic analysis of transcriptome data sets for aortae obtained from aged ApoE −/− mice fed a high‐fat diet revealed 50 overlapping genes that are enriched for ER stress‐ and UPR‐related pathways ENSG00000109133 ENSG00000100219 PMC8649520__F7 Schematic summary detailing the distinct UPR pathways regulated by hypercholesterolemia and aging within aortic and lung tissues in a murine model of atherosclerosis ENSG00000128272 PMC8651359__F7 Exploring the Therapeutic Mechanisms of Huzhang–Shanzha Herb Pair against Coronary Heart Disease by Network Pharmacology and Molecular Docking ENSG00000075142 ENSG00000172005 ENSG00000163497 ENSG00000174611 PMC4979440__F8 Role of EtOH-mediated cytotoxicity and neuroinflammation in context to HAND via cPLA2signaling in human astrocytes ENSG00000125538 ENSG00000130649 ENSG00000169429 PMC2651582__F1 Metabolic reprogramming in tumor cells ENSG00000169710 ENSG00000159399 PMC2788154__F1 Signaling pathways that lead from activated KIT and aggregated FcERI to mast cell responses ENSG00000157404 ENSG00000033327 ENSG00000213658 ENSG00000115415 ENSG00000291971 ENSG00000168610 ENSG00000010671 ENSG00000086730 ENSG00000141968 PMC3417476__F1 Cyclic AMP-mediated induction of Treg cells and suppression of effector T cells ENSG00000049768 PMC5516276__F4 Genes uniquely modulated in Fam13a−/− mice are involved in carbohydrate, lipid metabolism, and molecular transport network ENSG00000154342 ENSG00000133895 ENSG00000261371 ENSG00000137648 ENSG00000162695 ENSG00000184371 ENSG00000262814 ENSG00000143436 ENSG00000204936 ENSG00000132676 ENSG00000143995 ENSG00000143387 PMC3163944__F7 Disruption of the histone acetyltransferase MYST4 leads to a Noonan syndrome–like phenotype and hyperactivated MAPK signaling in humans and mice ENSG00000033327 ENSG00000170458 ENSG00000130522 ENSG00000183943 ENSG00000138798 ENSG00000155903 ENSG00000146648 ENSG00000081189 ENSG00000108061 ENSG00000158050 ENSG00000026103 PMC9499665__F1 Could BMPs Therapy Be Improved if BMPs Were Used in Composition Acting during Bone Formation in Endochondral Ossification? ENSG00000037965 ENSG00000291837 PMC5516276__F3 Genes uniquely modulated in Hhip+/− mice are involved in the connective tissue development and function network ENSG00000159197 ENSG00000136457 ENSG00000070882 ENSG00000160867 ENSG00000099139 ENSG00000157766 ENSG00000184113 ENSG00000184292 ENSG00000179593 ENSG00000166997 ENSG00000120937 ENSG00000134531 PMC8524061__F5 Multiple Roles of Fibroblast Growth Factor in Diabetic Nephropathy ENSG00000128272 ENSG00000105550 ENSG00000010810 ENSG00000096717 PMC8524061__F1 Multiple Roles of Fibroblast Growth Factor in Diabetic Nephropathy ENSG00000112977 ENSG00000169291 ENSG00000291971 PMC4397736__F1 Metabolic loops increase pathway multiplicity ENSG00000138604 ENSG00000010704 ENSG00000169299 PMC4397736__F2 Comparison between simulations and MFA experiments ENSG00000144063 ENSG00000122966 ENSG00000062485 PMC7564852__F3 Schematic depicting the molecular mechanism of co-activators involved in TCF/LEF-dependent Beta-catenin transcriptional activities and their functional consequences ENSG00000087245 ENSG00000182568 ENSG00000101255 ENSG00000136997 ENSG00000168036 ENSG00000168646 PMC8143357__F4 Adipose Stem Cells in Bone Regeneration and Bone Tissue Engineering ENSG00000170365 PMC7564852__F4 Schematic representing the molecular mechanism of transcriptional repression in TCF/LEF-dependent Wnt outcomes ENSG00000134982 ENSG00000168036 ENSG00000150457 ENSG00000164488 PMC3544722__F9 Enhancement of Auranofin-Induced Apoptosis in MCF-7 Human Breast Cells by Selenocystine, a Synergistic Inhibitor of Thioredoxin Reductase ENSG00000002330 PMC7564852__F5 Chromatin modifiers involved in Beta-catenin-dependent transcriptional regulation and their roles in the Wnt pathway ENSG00000117713 ENSG00000143379 ENSG00000004487 ENSG00000196591 ENSG00000104885 ENSG00000168036 ENSG00000186280 ENSG00000049618 ENSG00000096717 ENSG00000196367 PMC8323716__F1 Aberration of EZH2 signaling in cancer ENSG00000134574 ENSG00000148400 ENSG00000168610 ENSG00000100100 ENSG00000069667 PMC7337081__F1 Modular Organization of Cis-regulatory Control Information of Neurotransmitter Pathway Genes in Caenorhabditis elegans ENSG00000130234 ENSG00000168803 ENSG00000087085 PMC4142723__F2 SIRT6 as a master regulator of glucose metabolism ENSG00000177606 ENSG00000077463 PMC6390351__F8 Schematic representation of TLR and JAK-STAT pathways postulated in the slug I ENSG00000172936 ENSG00000131323 ENSG00000130159 ENSG00000175104 ENSG00000076604 PMC3097943__F1 Role IL-6 signaling in CCA inflammation-related epigenetic regulation ENSG00000186575 ENSG00000168610 ENSG00000146648 PMC8998991__F4 Mammary Gland: Basic Structure and Molecular Signaling during Development ENSG00000152266 ENSG00000019991 ENSG00000112964 ENSG00000109321 ENSG00000135111 ENSG00000168610 ENSG00000115415 ENSG00000163914 ENSG00000107485 ENSG00000146648 ENSG00000125968 ENSG00000140443 ENSG00000113494 PMC8583405__F7 Curcumin Alleviates the Senescence of Canine Bone Marrow Mesenchymal Stem Cells during In Vitro Expansion by Activating the Autophagy Pathway ENSG00000177169 ENSG00000145782 PMC4002295__F1 Schematic presentation of the rationale of targeting PARPs for cancer therapy ENSG00000012048 ENSG00000138385 ENSG00000139618 PMC4809369__F2 LIF/JAK/STAT3 signaling pathway in mouse ESC self-renewal ENSG00000137193 ENSG00000135111 ENSG00000128342 ENSG00000168505 ENSG00000168610 PMC6549576__F2 ERK signaling pathway was hyperactivated in the patient's tumor tissue ENSG00000182578 ENSG00000157404 ENSG00000291603 ENSG00000002330 ENSG00000291971 ENSG00000197565 ENSG00000111145 ENSG00000213658 ENSG00000120899 ENSG00000177606 ENSG00000136997 ENSG00000134853 ENSG00000146648 ENSG00000162104 ENSG00000123268 PMC7564852__F1 Wnt canonical (Beta-catenin-dependent) pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC4345324__F8 G-protein-coupled receptor controls steroid hormone signaling in cell membrane ENSG00000162607 PMC11015710__F2 Rosacea: Pathogenesis and Therapeutic Correlates ENSG00000087245 ENSG00000100985 PMC4323172__F1 Both ligands and receptors are single-pass transmembrane proteins composed of different structural domains ENSG00000140564 ENSG00000168214 ENSG00000138798 ENSG00000137845 PMC3608206__F4 Sox Family of Transcription Factors: Versatile Regulators of Stem and Progenitor Cell Fate ENSG00000176887 ENSG00000138798 ENSG00000128342 ENSG00000164690 ENSG00000134595 ENSG00000168610 PMC4809369__F6 Activin/Nodal signaling pathway in human ESC self-renewal ENSG00000156574 PMC4809369__F3 Canonical Wnt/Beta-catenin signaling pathway in mouse, rat and human ESC self-renewal ENSG00000071564 ENSG00000165556 ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000127528 ENSG00000113722 ENSG00000119715 PMC4809369__F4 FGF signaling pathway in mouse, rat and human ESC self-renewal PMC4151534__F2 IL-1A and IL-1B synthesis and signal transduction pathway ENSG00000115590 ENSG00000125538 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC3691915__F8 Regulators of mitochondrial biogenesis and function ENSG00000135218 ENSG00000042832 ENSG00000150907 ENSG00000169047 ENSG00000165264 PMC7378170__F1 Possible mechanisms through which major metabolic pathways contribute to the milk fat globule (MFG) size development in the mammary epithelial cell ENSG00000042832 ENSG00000173599 ENSG00000133027 PMC8235708__F1 Neuroinflammation and the Kynurenine Pathway in CNS Disease: Molecular Mechanisms and Therapeutic Implications ENSG00000111537 ENSG00000188676 PMC6386897__F4 MiRNA-gene-pathway interactive map ENSG00000117020 ENSG00000169750 ENSG00000276870 ENSG00000150907 ENSG00000177606 ENSG00000152689 ENSG00000166484 ENSG00000121879 ENSG00000171608 ENSG00000132356 ENSG00000184481 ENSG00000133818 PMC8193257__F1 Progress of Breast Cancer basic research in China ENSG00000135655 ENSG00000275385 ENSG00000111801 ENSG00000101000 ENSG00000125538 ENSG00000127324 ENSG00000163661 ENSG00000146648 ENSG00000185917 PMC8193257__F2 Progress of Breast Cancer basic research in China ENSG00000028277 ENSG00000108691 ENSG00000137273 ENSG00000105835 ENSG00000198793 ENSG00000197905 PMC6834480__F2 NKG2D/NKG2DL interaction activates NK cells ENSG00000291603 PMC3865866__F8 The FBXL2- and PTPL1-dependent regulation of the PI(3)K pathway ENSG00000169047 PMC3742550__F3 Intracellular 1-carbon metabolism (simplified), emphasizing pathways relevant to the text ENSG00000228716 ENSG00000100714 ENSG00000124275 ENSG00000116984 PMC9310545__F1 Signaling pathways producing pro-inflammatory cytokines ENSG00000278718 ENSG00000162711 ENSG00000088888 ENSG00000163568 ENSG00000276561 PMC7246017__F3 Complement activation and vasculopathy in coronavirus disease 2019 (COVID-19) ENSG00000110799 ENSG00000130234 PMC3187613__F5 Signaling pathways that regulate mammalian autophagy ENSG00000198382 ENSG00000002330 PMC7305712__F2 Metabolic liver disease in diabetes – From mechanisms to clinical trials ENSG00000171105 PMC6884041__F1 Neutrophil immunometabolism in cystic fibrosis ENSG00000162711 ENSG00000125538 ENSG00000185591 PMC2939720__F1 Viral hijacking of the host ubiquitin system to evade interferon responses ENSG00000183735 ENSG00000213928 ENSG00000239732 ENSG00000187608 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC6834480__F5 Strategies for targeting the NKG2D/NKG2DL axis for cancer immunotherapy ENSG00000149311 ENSG00000175054 ENSG00000087245 ENSG00000157227 ENSG00000137845 PMC6770832__F1 Map of potential pathways and their potential interactions activated by a soluble factor- radiation-induced bystander effect (RIBE) signal ENSG00000102871 ENSG00000130522 ENSG00000135446 ENSG00000132646 ENSG00000082512 ENSG00000123374 ENSG00000157625 ENSG00000105810 ENSG00000127191 PMC5288579__F10 Group I Paks as components of the Ncad/Cdo signaling pathway ENSG00000070831 ENSG00000149269 ENSG00000170558 ENSG00000168036 PMC11938789__F7 The role of ZBTB6 in BC proliferation ENSG00000168610 ENSG00000186130 PMC5336479__F5 Deep Coverage of Global Protein Expression and Phosphorylation in Breast Tumor Cell Lines using TMT 10-plex Isobaric Labeling ENSG00000070831 ENSG00000065361 ENSG00000198793 ENSG00000169047 ENSG00000123374 ENSG00000123595 ENSG00000178568 ENSG00000160691 PMC6770832__F6 Hypothetical signalling pathway that illustrates how the various pathways in this review may be connected, which is partially informed by preliminary research ENSG00000105329 ENSG00000026103 PMC9095530__F2 Molecular insights into the pathophysiology of doxorubicin-induced cardiotoxicity: a graphical representation ENSG00000102871 ENSG00000166278 ENSG00000168040 ENSG00000168404 ENSG00000168610 ENSG00000285379 PMC8508555__F4 Sulforaphane: A Broccoli Bioactive Phytocompound with Cancer Preventive Potential ENSG00000181019 ENSG00000175793 ENSG00000178573 ENSG00000079999 PMC3197649__F6 Patient-Specific Data Fusion Defines Prognostic Cancer Subtypes ENSG00000130957 ENSG00000196388 ENSG00000157404 ENSG00000109906 ENSG00000166068 ENSG00000166716 ENSG00000103479 ENSG00000144579 ENSG00000135709 ENSG00000140553 ENSG00000078900 ENSG00000082512 ENSG00000197943 ENSG00000140859 ENSG00000101197 ENSG00000139687 ENSG00000100603 ENSG00000130939 ENSG00000132305 ENSG00000137275 ENSG00000169439 ENSG00000120693 ENSG00000106299 ENSG00000126457 ENSG00000135900 ENSG00000101365 ENSG00000133216 ENSG00000066468 ENSG00000277586 ENSG00000120899 ENSG00000134057 ENSG00000116106 ENSG00000183020 ENSG00000073734 ENSG00000105426 ENSG00000141456 PMC10541724__F7 Schematic illustration showing that CSSC-EVs mediated the LESC phenotype by regulating the Notch1 pathway through miRNAs ENSG00000148400 ENSG00000114315 PMC3197649__F3 Patient-Specific Data Fusion Defines Prognostic Cancer Subtypes ENSG00000182481 ENSG00000101367 ENSG00000178999 ENSG00000291971 ENSG00000167513 ENSG00000163565 ENSG00000115816 ENSG00000073111 ENSG00000145386 ENSG00000172315 ENSG00000196396 ENSG00000183765 ENSG00000137807 ENSG00000180228 ENSG00000178764 ENSG00000089685 ENSG00000171453 ENSG00000104320 ENSG00000124249 ENSG00000123374 ENSG00000076641 ENSG00000112029 ENSG00000134690 ENSG00000253729 ENSG00000115163 ENSG00000225190 ENSG00000101057 ENSG00000117399 ENSG00000198901 ENSG00000048392 ENSG00000277586 ENSG00000156802 ENSG00000291748 ENSG00000197299 ENSG00000147601 ENSG00000165156 ENSG00000124171 ENSG00000175305 PMC8826423__F1 Interaction of ncRNA and Epigenetic Modifications in Gastric Cancer: Focus on Histone Modification ENSG00000137673 ENSG00000134982 ENSG00000163739 ENSG00000013588 ENSG00000168036 ENSG00000123908 PMC9609612__F9 Therapeutic Approach of Melatonin against Omicron and Some Other Variants of SARS-CoV-2 ENSG00000088888 ENSG00000189403 ENSG00000169914 ENSG00000096717 ENSG00000069667 PMC9095530__F6 Molecular insights into the pathophysiology of doxorubicin-induced cardiotoxicity: a graphical representation ENSG00000137275 ENSG00000102871 ENSG00000285121 ENSG00000168040 ENSG00000164305 ENSG00000026103 PMC9124578__F3 Origins and roles of osteoclasts in bone development, homeostasis and repair ENSG00000182578 ENSG00000281324 ENSG00000162337 ENSG00000167941 ENSG00000002745 ENSG00000187764 ENSG00000075213 PMC2854308__F1 Signaling complexes induced by TNFA to mediate NFKB activation, apoptosis and necroptosis ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000127191 PMC3824536__F1 Druggable Drivers of Lung Cancer ENSG00000160867 PMC11356883__F4 Outline of the DTSAs biosynthetic pathway in Dendrobium species ENSG00000105552 PMC7434719__F1 Diagrammatic presentation of conserved domains of MUC2, MUC6, MUC5AC, and MUC5B ENSG00000291363 ENSG00000184956 ENSG00000117983 ENSG00000293532 PMC3493930__F8 Mechanisms by which AP-1 transcription factor regulates LY6K expression, which activates the ERK signaling pathway to mediate cell invasive motility and metastasis in human breast cancer cells ENSG00000135903 ENSG00000145321 ENSG00000160886 PMC7465197__F2 Number of transcriptional factors positively or negatively regulate ARF transcription ENSG00000168283 ENSG00000121068 ENSG00000136997 ENSG00000146648 ENSG00000282899 PMC11314424__F3 Diagram summarizing the effects of salidroside (SAL) on cellular signaling pathways PMC9523165__F1 Anticancer potential of cryptotanshinone on breast cancer treatment; A narrative review ENSG00000150907 ENSG00000169047 ENSG00000140443 PMC5528296__F2 PI3K signalling regulates both choline and glucose metabolism ENSG00000198793 ENSG00000136997 ENSG00000078237 PMC4975451__F8 PI-103 and Quercetin Attenuate PI3K-AKT Signaling Pathway in T- Cell Lymphoma Exposed to Hydrogen Peroxide ENSG00000002330 PMC5923349__F1 Hippo signaling pathway in Drosophila and mammals ENSG00000150457 ENSG00000131023 PMC8859461__F1 Type-I Interferon Signaling in Fanconi Anemia ENSG00000131944 ENSG00000144554 ENSG00000181544 ENSG00000187790 ENSG00000115392 ENSG00000187741 ENSG00000112039 ENSG00000158169 ENSG00000276787 PMC5923349__F2 Hippo signaling pathway and the anti-neoplastic immune response ENSG00000108691 ENSG00000163739 ENSG00000184371 PMC11274826__F6 Osteopontin: A Key Multifaceted Regulator in Tumor Progression and Immunomodulation ENSG00000177575 ENSG00000091972 ENSG00000170558 ENSG00000138755 ENSG00000078098 PMC5923349__F3 Hippo signaling immunomodulatory functions ENSG00000081041 ENSG00000163739 ENSG00000172936 ENSG00000091106 ENSG00000184216 ENSG00000145391 PMC11274826__F3 OPN in the regulation of various signaling pathways ENSG00000169554 ENSG00000128272 ENSG00000157764 ENSG00000198793 ENSG00000168036 ENSG00000168610 ENSG00000146648 PMC5923349__F4 Leukocyte-intrinsic Hippo pathway functions ENSG00000177455 ENSG00000186716 ENSG00000126353 ENSG00000049768 ENSG00000131023 PMC11274826__F4 Diagrammatic representation of multifaceted function of OPN in various tumors ENSG00000125285 ENSG00000128272 ENSG00000170558 ENSG00000198793 ENSG00000026508 ENSG00000168036 ENSG00000146648 PMC6927982__F7 Predicted pathway illustrated that IL1B and MALT1 were significantly upregulated in the NF-kappa B signalling pathway ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC6562915__F2 Illustration of the main signaling pathways activated upon Ang2 binding to endothelial cells ENSG00000182511 ENSG00000010810 ENSG00000150907 PMC4546937__F2 COMMENTARY: IL-4 AND IL-13 RECEPTORS AND SIGNALING ENSG00000103266 ENSG00000123496 ENSG00000168036 ENSG00000131724 PMC4546937__F3 COMMENTARY: IL-4 AND IL-13 RECEPTORS AND SIGNALING ENSG00000171150 ENSG00000155792 ENSG00000167965 ENSG00000105639 PMC7103888__F2 Critical Roles of Deubiquitinating Enzymes in the Nervous System and Neurodegenerative Disorders ENSG00000124422 ENSG00000152484 ENSG00000145147 ENSG00000055483 ENSG00000109189 ENSG00000077279 ENSG00000101557 ENSG00000184979 ENSG00000077254 ENSG00000115415 ENSG00000090686 ENSG00000172936 ENSG00000083799 ENSG00000175104 PMC3160087__F7 Model of the role of the Nodal and Cripto signaling pathways in mouse XEN cell differentiation ENSG00000241186 ENSG00000156574 PMC8400201__F1 Autophagy in Anti-Cancer and Health Promoting Effects of Cordycepin ENSG00000126775 ENSG00000198793 PMC7969609__F9 MAPK signaling pathway ENSG00000087095 ENSG00000170458 ENSG00000102871 ENSG00000172936 ENSG00000130159 ENSG00000127191 ENSG00000111816 ENSG00000081189 ENSG00000135517 ENSG00000026103 PMC8403172__F7 The proposed regulatory mechanism of ARRB1 in this study ENSG00000128272 ENSG00000144895 PMC8621917__F2 Rutin (Bioflavonoid) as Cell Signaling Pathway Modulator: Prospects in Treatment and Chemoprevention ENSG00000002330 ENSG00000198793 ENSG00000168036 ENSG00000168610 PMC8125972__F1 Impact of Epigenetic Modifications in Myeloid Malignancies ENSG00000122025 ENSG00000171456 ENSG00000181163 ENSG00000108799 ENSG00000178691 ENSG00000179348 PMC3913902__F4 Induction of NLRP3 inflammasome complex by the inorganic crystal HZ ENSG00000162711 ENSG00000291971 ENSG00000265972 PMC2360674__F8 Schematic of porphyrin-synthetic pathway to illustrate potential control points for increased PpIX accumulation ENSG00000144410 ENSG00000198125 PMC8520510__F4 Identification of cell cycle as the critical pathway modulated by exosome-derived microRNAs in gallbladder carcinoma ENSG00000029363 ENSG00000274211 ENSG00000228716 ENSG00000253293 ENSG00000147649 ENSG00000111859 ENSG00000169047 ENSG00000103222 ENSG00000073111 ENSG00000171791 ENSG00000165527 ENSG00000116962 ENSG00000136826 ENSG00000012048 ENSG00000168283 ENSG00000125398 ENSG00000136997 ENSG00000196639 ENSG00000001626 ENSG00000105810 ENSG00000185008 ENSG00000139687 ENSG00000155760 ENSG00000140443 ENSG00000162552 ENSG00000262785 ENSG00000169554 ENSG00000164109 ENSG00000198561 ENSG00000100697 ENSG00000134748 ENSG00000114993 ENSG00000100387 ENSG00000171914 ENSG00000026508 ENSG00000076716 ENSG00000067955 ENSG00000130669 ENSG00000157554 ENSG00000171855 ENSG00000079387 ENSG00000120833 ENSG00000163629 ENSG00000170558 ENSG00000117139 ENSG00000196591 ENSG00000150093 ENSG00000176105 ENSG00000112715 ENSG00000089159 ENSG00000124782 ENSG00000160049 ENSG00000161955 ENSG00000112242 ENSG00000046889 ENSG00000113318 ENSG00000196935 ENSG00000291837 ENSG00000132383 ENSG00000284571 ENSG00000138182 ENSG00000185591 ENSG00000259207 ENSG00000157764 ENSG00000113070 ENSG00000060237 ENSG00000137193 ENSG00000124766 ENSG00000168487 ENSG00000141052 ENSG00000067900 ENSG00000162594 ENSG00000065328 ENSG00000135446 ENSG00000010810 ENSG00000183742 ENSG00000128602 ENSG00000131196 ENSG00000163517 ENSG00000114739 ENSG00000176619 PMC8520510__F6 Identification of cell cycle as the critical pathway modulated by exosome-derived microRNAs in gallbladder carcinoma ENSG00000145604 ENSG00000118007 ENSG00000101972 ENSG00000108055 ENSG00000179091 ENSG00000132646 ENSG00000115942 ENSG00000123374 ENSG00000073111 ENSG00000277273 ENSG00000093009 PMC4676172__F2 Wnt/Beta-catenin signaling and directly related pathways affected by genetic-driven and/or gene expression activation or suppression in primary and/or recurrent tumors of 4 HCC patients ENSG00000087095 ENSG00000156076 ENSG00000281324 ENSG00000137673 ENSG00000162337 ENSG00000134982 ENSG00000291971 ENSG00000124766 ENSG00000168036 ENSG00000106483 ENSG00000196628 ENSG00000110693 ENSG00000127445 ENSG00000125398 ENSG00000026508 ENSG00000004961 PMC7436103__F7 lncRNA target pathway network in AGPS-silenced U251 cells ENSG00000261857 PMC9075737__F2 Benefits of Curcumin in the Vasculature: A Therapeutic Candidate for Vascular Remodeling in Arterial Hypertension and Pulmonary Arterial Hypertension? ENSG00000148346 ENSG00000087245 ENSG00000132646 ENSG00000185591 ENSG00000100985 PMC7436103__F5 Signaling transduction and pathway network of co-expressed lncRNAs and mRNAs in AGPS-silenced U251 cells ENSG00000104812 ENSG00000105835 ENSG00000162433 ENSG00000140575 ENSG00000198793 ENSG00000103024 ENSG00000121879 ENSG00000089159 ENSG00000137801 ENSG00000179958 ENSG00000148082 ENSG00000197594 ENSG00000125538 ENSG00000120137 ENSG00000169429 ENSG00000154721 ENSG00000115594 ENSG00000140443 ENSG00000164342 ENSG00000145824 ENSG00000091879 ENSG00000109814 ENSG00000117020 ENSG00000108691 ENSG00000118785 ENSG00000124882 ENSG00000162409 ENSG00000146592 ENSG00000177606 ENSG00000171914 ENSG00000026508 ENSG00000146648 PMC6642076__F1 The complement system, showing approximately 50 directly involved soluble and membrane-bound complement proteins ENSG00000039537 ENSG00000113600 ENSG00000173372 ENSG00000291559 ENSG00000203710 ENSG00000244731 ENSG00000166278 ENSG00000122194 ENSG00000132693 ENSG00000165471 ENSG00000182326 PMC11790539__F2 Pyroptosis signaling pathway ENSG00000278718 ENSG00000198793 PMC7940950__F2 Four genes (RAC2, CXCR4, CXCL2, and CCL18) were significantly enriched in the chemokine signaling pathway ENSG00000163930 ENSG00000169291 ENSG00000002330 ENSG00000113263 PMC4859220__F3 Poor tumor T cell infiltration ENSG00000169245 ENSG00000163739 ENSG00000138755 ENSG00000168036 ENSG00000162772 ENSG00000277943 PMC3679547__F1 Canonical pathway analysis ENSG00000138075 ENSG00000107562 ENSG00000125735 ENSG00000113161 ENSG00000122194 ENSG00000168610 ENSG00000121966 ENSG00000179295 ENSG00000073060 ENSG00000130164 ENSG00000198670 ENSG00000136697 ENSG00000038945 ENSG00000143921 PMC6333895__F6 Cell migration elicited by chemotactic GPCRs via the GBG–P-REX1–Rac pathway is mainly mediated by Gi over Gq or G13 because of the tight control that GAq and GA13 subunits exert on GBG ENSG00000116741 ENSG00000198670 ENSG00000121966 PMC12202350__F11 The molecular mechanism underlying EM-2 inhibiting the proliferation of LC and BC cells ENSG00000149311 PMC6792490__F7 Colorectal cancer pathway enriched in KEGG ENSG00000132906 ENSG00000157554 ENSG00000002330 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000164305 ENSG00000122008 PMC8584291__F1 Senolytics: A Novel Strategy for Neuroprotection in ALS? ENSG00000002330 ENSG00000135446 ENSG00000123374 ENSG00000120868 ENSG00000105810 ENSG00000168040 ENSG00000026103 PMC4859220__F4 Scientific rationales of potential therapeutic combinations with PD pathway blockade ENSG00000102962 ENSG00000107562 ENSG00000089692 ENSG00000181847 ENSG00000134982 ENSG00000163599 ENSG00000121966 PMC5397509__F1 Central role of RTA in reactivation of Kaposi’s sarcoma-associated herpesvirus (KSHV) from latency leading to lytic cycle ENSG00000127445 ENSG00000147862 ENSG00000168610 ENSG00000140464 ENSG00000138385 PMC4993636__F4 Cellular Organization and Cytoskeletal Regulation of the Hippo Signaling Network ENSG00000126016 ENSG00000291971 ENSG00000163914 ENSG00000144791 PMC4993636__F2 Cellular Organization and Cytoskeletal Regulation of the Hippo Signaling Network ENSG00000126016 ENSG00000132849 PMC5986855__F3 Downregulation of VRK1 by DRAM1 in the autophagic pathway induced by p53 and deactivation of p53 by phosphatases and ubiquitin ligases the proteasome in DNA damage response ENSG00000149311 ENSG00000100749 ENSG00000120875 ENSG00000136048 PMC5210567__F4 KEGG pathway maps for (A) non-small cell lung cancer (hsa05223) and (B) EGFR tyrosine kinase inhibitor resistance (hsa01521) ENSG00000132906 ENSG00000189283 ENSG00000167601 ENSG00000113905 ENSG00000002330 ENSG00000146648 ENSG00000196712 PMC8002743__F6 Detailed schematic models representing changes in cellular processes with CdSe/ZnS QDs or InP/ZnS QDs in the budding yeast PMC9547189__AF1 miR21 modulates the Hippo signaling pathway via interference with PP2A BB to inhibit trophoblast invasion and cause preeclampsia ENSG00000168036 ENSG00000131023 PMC7378891__F4 Canonical Type I IFN and non-canonical JAK1-and IFNAR2-independent IFNB signaling pathways ENSG00000275214 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC10495361__F5 Joint analysis of Chinese yew seed transcriptome, proteome, and metabolome ENSG00000120705 ENSG00000115268 ENSG00000196839 ENSG00000140505 ENSG00000198931 ENSG00000173083 ENSG00000167965 ENSG00000169032 ENSG00000276043 ENSG00000156110 ENSG00000113558 ENSG00000158825 ENSG00000062485 PMC10495361__F6 Summary diagram of specific metabolic pathways involved in Chinese yew seed germination ENSG00000160752 ENSG00000197713 ENSG00000073578 ENSG00000152904 PMC12180913__F5 PI3K/Akt signaling pathway in cell migration ENSG00000070831 PMC12180913__F6 TGFB/Smad signaling pathway in cell migration ENSG00000149968 ENSG00000170558 ENSG00000100985 PMC12180913__F7 Wnt/Beta-catenin signaling pathway in cell migration ENSG00000087245 ENSG00000281324 ENSG00000137673 ENSG00000162337 ENSG00000134982 ENSG00000170558 ENSG00000168036 ENSG00000100985 PMC4396743__F7 Proposed model of signaling pathways activated in primary NHP microglia in response to B ENSG00000174125 ENSG00000108691 ENSG00000167207 ENSG00000187554 ENSG00000169429 ENSG00000172936 ENSG00000136869 PMC5758607__F8 A schematic for TMZ resistance induced by SCD1 mediated the activation of Akt/GSK3B/Beta-catenin signaling axis ENSG00000170430 ENSG00000168036 PMC3561517__F8 Overview of the recruitment and modification of PCNA and Pol D by RNF8 involving different DNA damage pathways ENSG00000132646 ENSG00000070950 ENSG00000112130 PMC11790539__F5 Ferroptosis signaling pathway ENSG00000151012 ENSG00000167468 ENSG00000175832 PMC8161134__F1 Genetics and Epigenetics of One-Carbon Metabolism Pathway in Autism Spectrum Disorder: A Sex-Specific Brain Epigenome? ENSG00000228716 PMC11790539__F6 Cuprotosis signaling pathway ENSG00000149311 ENSG00000137714 PMC2643336__F3 From the diet to the nucleus: Vitamin A and TGFB join efforts at the mucosal interface of the intestine ENSG00000049768 ENSG00000168610 PMC11790539__F3 Necroptosis signaling pathway ENSG00000137275 ENSG00000102871 ENSG00000168404 PMC11790539__F4 Autophagy signaling pathway ENSG00000157764 ENSG00000198793 ENSG00000144848 ENSG00000163694 ENSG00000057663 PMC8238154__F8 CF monocyte-derived macrophages have an attenuated response to extracellular vesicles secreted by airway epithelial cells ENSG00000094631 ENSG00000102962 ENSG00000213928 ENSG00000163739 ENSG00000159388 ENSG00000162772 ENSG00000160613 ENSG00000106546 ENSG00000069667 ENSG00000170365 ENSG00000077150 ENSG00000153879 ENSG00000150907 ENSG00000169429 ENSG00000176046 ENSG00000148840 ENSG00000283060 ENSG00000113645 ENSG00000137673 ENSG00000197635 ENSG00000100906 ENSG00000204103 ENSG00000148400 ENSG00000221869 ENSG00000132170 ENSG00000197461 ENSG00000106459 ENSG00000143387 ENSG00000153487 ENSG00000108691 ENSG00000128272 ENSG00000182240 PMC3348964__F1 Metabolic pathway for disulfiram in humans ENSG00000172680 ENSG00000015285 ENSG00000062485 PMC6547757__F10 Impact of flight condition on expression of crystallins in the network of proteins associated with ophthalmic disease as defined by Ingenuity Pathway Analysis (IPA, https://www.qiagenbioinformatics.com/products/ingenuitypathway-analysis) ENSG00000163882 ENSG00000178573 ENSG00000156531 ENSG00000188130 ENSG00000163684 ENSG00000153561 ENSG00000170515 ENSG00000155438 ENSG00000114383 ENSG00000132819 ENSG00000108255 ENSG00000108312 PMC8238154__F9 CF monocyte-derived macrophages have an attenuated response to extracellular vesicles secreted by airway epithelial cells ENSG00000184381 ENSG00000096996 ENSG00000102962 ENSG00000138755 ENSG00000171049 ENSG00000277263 ENSG00000232629 PMC3652659__F3 Marginal zone B cells: virtues of innatelike antibody-producing lymphocytes ENSG00000111537 ENSG00000170458 ENSG00000145321 PMC5741957__F3 Oxidative phosphorelation metabolic pathway ENSG00000006695 ENSG00000160194 ENSG00000143252 ENSG00000090402 ENSG00000073578 ENSG00000130414 ENSG00000213619 ENSG00000138495 ENSG00000117118 ENSG00000166260 ENSG00000292058 ENSG00000105669 PMC12180913__F2 Cell migration and function during normal wound healing ENSG00000019991 ENSG00000108691 ENSG00000189403 PMC8238154__F5 CF monocyte-derived macrophages have an attenuated response to extracellular vesicles secreted by airway epithelial cells ENSG00000111537 ENSG00000163235 PMC12180913__F4 Rho GTPase signaling pathway in cell migration ENSG00000070831 ENSG00000163914 PMC8859437__F3 Aldosterone-Regulated Sodium Transport and Blood Pressure ENSG00000168066 ENSG00000291971 ENSG00000146648 PMC9501954__F2 P16INK4A—More Than a Senescence Marker ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC12109847__F2 AKT signaling pathway is known to be regulated by miR-21 through the targeting and suppression of the tumor suppressor phosphatase and tensin homolog (PTEN) PMC12109847__F3 MiR-21 modulates the MAPK/MEK/ERK signaling pathway directly by downregulating the SPRY and DUSPs that normally suppress ERK activation ENSG00000115415 PMC4584352__F1 Anti-oxidative effects of astaxanthin in neurological diseases ENSG00000181019 ENSG00000185591 ENSG00000079999 PMC6044036__F1 Metabolic cycles involved in methionine metabolism ENSG00000173599 ENSG00000116096 ENSG00000116984 PMC6044036__F2 SAM treatment during hepatocarcinogenesis ENSG00000136997 PMC9032069__F7 Ginsenoside Rh4 Suppresses Metastasis of Gastric Cancer via SIX1-Dependent TGFB/Smad2/3 Signaling Pathway ENSG00000126778 ENSG00000062485 PMC6073374__F1 Mechanistic target of rapamycin (mTOR) signaling pathway ENSG00000150907 ENSG00000155792 ENSG00000281518 ENSG00000141564 ENSG00000184481 PMC9310656__F2 Gut Microbiota: A Novel Player in Autoimmune Hepatitis ENSG00000162711 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000140465 ENSG00000106546 ENSG00000179921 PMC9273267__F1 Ferroptosis at the crossroads of tumor-host interactions, metastasis, and therapy response ENSG00000168003 ENSG00000138449 ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000187855 ENSG00000115107 PMC9096094__F5 Betaine Regulates the Production of Reactive Oxygen Species Through Wnt10b Signaling in the Liver of Zebrafish ENSG00000169884 ENSG00000168036 PMC7649723__F1 SARS-CoV-2 replication ENSG00000130234 ENSG00000184012 PMC5968842__F9 Schematic diagram of how LIPUS promotes the Schwann cell viability and proliferation signaling pathway ENSG00000168036 PMC8248532__F8 Cryptotanshinone Inhibits the Growth of HCT116 Colorectal Cancer Cells Through Endoplasmic Reticulum Stress-Mediated Autophagy ENSG00000065833 ENSG00000145782 PMC4523298__F3 Conserved and differential networks for the proteins in the PI3K-AKT kinase pathway between breast and ovarian cancer cell lines computed using a Bayesian FDR set to 0.10 ENSG00000177606 ENSG00000170430 ENSG00000076706 ENSG00000146648 PMC7409924__F1 Methylene blue may have a role in the treatment of COVID-19 ENSG00000122194 PMC3703536__F1 Highlights of 10 years of immunology in Nature Reviews Immunology ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC4523298__F2 Significant edges for the proteins in the PI3K-AKT kinase pathway for breast (a) and ovarian cancer cell lines (b) computed using a Bayesian FDR of 0.10 ENSG00000076706 ENSG00000132698 PMC6647277__F5 Curcumin actions on the WNT pathway in cancer therapy ENSG00000002330 ENSG00000198793 ENSG00000168036 ENSG00000168610 PMC12181166__F4 mTORC1 signaling pathway showing genes (or rather their gene products) that reached exome-wide significance in black ENSG00000177169 ENSG00000160584 ENSG00000198793 ENSG00000052795 ENSG00000155792 ENSG00000167965 PMC6647277__F6 Beneficial role of curcumin in cancer ENSG00000134982 ENSG00000168610 PMC9021355__F2 Pathological features of tissues and cell populations during cancer cachexia ENSG00000117525 ENSG00000092621 ENSG00000150907 ENSG00000169047 ENSG00000198793 ENSG00000128342 PMC8674571__F1 The Immune System in Health and Disease by Members of the Bone Morphogenetic Protein Family ENSG00000107779 ENSG00000170365 ENSG00000139567 ENSG00000175104 ENSG00000076604 PMC7139812__F1 Pathological implications of amyloidB (AB), reactive oxygen species (ROS), and neuroinflammation and their role in potential therapeutic approaches for cerebral amyloid angiopathy (CAA) and Alzheimer’s disease (AD) ENSG00000281244 PMC6073374__F2 Sonic Hedgehog (SHH)/Patched (PTCH1) and WNT signaling pathways ENSG00000106571 ENSG00000134982 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC3191732__F11 Hydrolytic metabolism of 2-AG and PG-Gs ENSG00000100997 ENSG00000163686 PMC3703536__F5 Highlights of 10 years of immunology in Nature Reviews Immunology ENSG00000239732 ENSG00000111537 ENSG00000167207 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000168610 ENSG00000164342 PMC8716463__F1 DNA Damage and Repair Deficiency in ALS/FTD-Associated Neurodegeneration: From Molecular Mechanisms to Therapeutic Implication ENSG00000143799 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000113318 ENSG00000132646 ENSG00000051180 ENSG00000140398 ENSG00000095002 ENSG00000138385 ENSG00000139618 PMC8499579__F7 Niraparib exhibits a synergistic anti-tumor effect with PD-L1 blockade by inducing an immune response in ovarian cancer ENSG00000169245 ENSG00000183735 ENSG00000164430 PMC3178084__F2 Runx2-deficient cells exhibit suppression of genes by insulin at multiple stages of the signaling pathway ENSG00000130164 ENSG00000115904 ENSG00000140443 PMC7665242__F4 Cooperative participation of epigenomic and genomic alterations in the clinicopathological diversity of gastric adenocarcinomas: significance of cell adhesion and epithelial–mesenchymal transition-related signaling pathways ENSG00000019991 ENSG00000111837 ENSG00000146648 PMC3429538__F5 Highlights from this issue ENSG00000132591 ENSG00000136048 PMC5225396__F1 Possible roles of lncRNAs played in the context of RNA-RNA interactions ENSG00000114450 ENSG00000160710 ENSG00000204217 ENSG00000089053 PMC6843035__F5 Phosphoinositide signaling pathway in renal collecting duct cells ENSG00000027075 ENSG00000143393 ENSG00000143398 ENSG00000175591 ENSG00000186111 ENSG00000184304 ENSG00000101333 PMC3946772__F1 Non Alcoholic Fatty Liver Disease, Hepatic Insulin Resistance and Type 2 Diabetes ENSG00000100344 ENSG00000198670 ENSG00000123689 PMC3985519__F3 Down-regulation of the clotting cascade by the protein C pathway ENSG00000134982 PMC2819802__F1 Activation of apoptotic and survival pathways by TNF ENSG00000102871 ENSG00000099860 ENSG00000168040 ENSG00000127191 PMC5855617__F1 Cancer-fighting mechanisms of BP ENSG00000167601 PMC9468722__F3 Strategies for Mammalian Mesenchymal Stem Cells Differentiation into Primordial Germ Cell-Like Cells: A Review ENSG00000121207 ENSG00000121039 ENSG00000128918 ENSG00000143320 ENSG00000146857 PMC7412871__F3 Transcriptional Regulators of Ca2+ Homeostasis ENSG00000104856 ENSG00000163624 ENSG00000186716 ENSG00000185591 ENSG00000167182 ENSG00000101290 PMC9468722__F4 Strategies for Mammalian Mesenchymal Stem Cells Differentiation into Primordial Germ Cell-Like Cells: A Review ENSG00000170365 ENSG00000152670 ENSG00000146857 ENSG00000157625 PMC11565213__F2 PIK3CA gene mutation activation of PI3K/AKT/mTOR signaling pathway will resist the action of anti-EGFR monoclonal antibody on EGFR signaling pathway, resulting in resistance to EGFR monoclonal antibody in colorectal cancer patients ENSG00000157764 ENSG00000198793 ENSG00000121879 ENSG00000146648 PMC9028087__F1 MD2 AMP(K)s up the link between lipid accumulation and inflammation in NAFLD ENSG00000183735 ENSG00000172936 ENSG00000136869 PMC2811176__F2 Cytosine Methylation Dysregulation in Neonates Following Intrauterine Growth Restriction ENSG00000099954 ENSG00000124535 ENSG00000113889 ENSG00000138459 ENSG00000173145 ENSG00000164414 ENSG00000132793 ENSG00000105329 ENSG00000283510 ENSG00000117174 ENSG00000120054 ENSG00000278224 ENSG00000053372 ENSG00000106245 ENSG00000122121 PMC3570673__F6 SIRT1 in the brain is involved in a number of processes that affect neuronal health, neurogenesis, and behavior ENSG00000100811 ENSG00000284774 ENSG00000197386 ENSG00000185591 ENSG00000177551 ENSG00000096717 ENSG00000137845 PMC4770749__F9 BH3-mimetic gossypol and noncytotoxic doses of valproic acid induce apoptosis by suppressing cyclin-A2/Akt/FOXO3a signaling ENSG00000123374 ENSG00000168040 ENSG00000145386 PMC8789313__F2 Helminth Therapy for Immune-Mediated Inflammatory Diseases: Current and Future Perspectives ENSG00000162594 ENSG00000167207 ENSG00000173599 ENSG00000145777 ENSG00000116525 PMC10743675__F3 Osteobiologies for Spinal Fusion from Biological Mechanisms to Clinical Applications: A Narrative Review ENSG00000281324 ENSG00000125398 ENSG00000162337 ENSG00000283780 ENSG00000128602 ENSG00000163501 PMC10743675__F4 Bone morphogenetic proteins (BMPs) signaling pathways ENSG00000152266 ENSG00000281324 ENSG00000105329 ENSG00000162337 ENSG00000134982 ENSG00000139269 ENSG00000156574 ENSG00000135414 ENSG00000163083 ENSG00000266524 ENSG00000163217 ENSG00000123999 ENSG00000164404 ENSG00000175189 ENSG00000167941 ENSG00000183682 ENSG00000204217 ENSG00000130513 PMC6361956__F5 Cerebellum (CB)-specific biological processes in Alzheimer’s disease (AD) brain ENSG00000067141 ENSG00000142192 ENSG00000291560 ENSG00000074317 ENSG00000112335 ENSG00000063854 ENSG00000143878 ENSG00000106299 ENSG00000165280 ENSG00000242616 ENSG00000198168 ENSG00000291720 ENSG00000087460 ENSG00000143858 ENSG00000107223 ENSG00000105664 ENSG00000065518 ENSG00000197971 ENSG00000102898 ENSG00000154654 ENSG00000122971 ENSG00000171533 ENSG00000145819 ENSG00000154096 PMC5479827__F3 Regulation network of the lectin genes related to immune activities ENSG00000100906 ENSG00000073350 ENSG00000100345 ENSG00000100852 ENSG00000049283 ENSG00000142273 ENSG00000117399 ENSG00000184500 ENSG00000058600 ENSG00000166523 ENSG00000183020 ENSG00000038532 ENSG00000066427 ENSG00000184216 PMC11770925__F4 Components-disease-target gene-pathway network ENSG00000157404 ENSG00000070831 ENSG00000291971 ENSG00000280908 ENSG00000164305 ENSG00000129214 ENSG00000170231 ENSG00000087245 ENSG00000262406 ENSG00000171105 ENSG00000142627 ENSG00000197635 ENSG00000198408 ENSG00000120915 ENSG00000196839 ENSG00000257335 ENSG00000197616 ENSG00000105639 ENSG00000007171 ENSG00000132170 ENSG00000147099 ENSG00000156110 ENSG00000115263 ENSG00000146648 ENSG00000090659 PMC7419604__F2 Communication between the GI tract and the brain ENSG00000125538 ENSG00000131096 ENSG00000106546 PMC6471940__F4 Molecular signaling in cancer ENSG00000168036 ENSG00000114315 PMC4923163__F3 BDNF and TrkB signaling pathway PMC10978726__F3 SKP2-p27 axis ENSG00000145604 ENSG00000113558 ENSG00000123374 PMC7996029__F2 Therapeutic potential of targeting exchange protein directly activated by cyclic adenosine 3′,5′-monophosphate (Epac) for central nervous system trauma ENSG00000198793 ENSG00000163914 ENSG00000118520 PMC4432743__F8 ERK pathway signaling and outcomes in the M ENSG00000118520 PMC3371005__F6 Genome-Wide Association for Sensitivity to Chronic Oxidative Stress in Drosophila melanogaster ENSG00000145362 ENSG00000144596 ENSG00000087095 ENSG00000101670 ENSG00000197429 ENSG00000149091 ENSG00000177954 ENSG00000060558 ENSG00000141564 ENSG00000182621 ENSG00000115884 ENSG00000138193 ENSG00000143149 ENSG00000118094 ENSG00000177084 ENSG00000146648 PMC10978726__F4 Involvement of SKP2 in hematological malignanices ENSG00000145604 ENSG00000033327 ENSG00000186716 ENSG00000136997 ENSG00000123374 PMC8770806__F2 Applications and Immunological Effects of Quantum Dots on Respiratory System ENSG00000108691 ENSG00000137033 ENSG00000125538 PMC11781165__F1 Intestinal bacteria and their metabolites on physical barriers ENSG00000134982 ENSG00000168036 ENSG00000172936 ENSG00000136869 ENSG00000124762 PMC9663828__F6 Tumor suppressor DEAR1 regulates mammary epithelial cell fate and predicts early onset and metastasis in triple negative breast cancer ENSG00000019549 PMC7702050__F2 RNAi‐mediated regulation of gene expression ENSG00000090402 ENSG00000124571 ENSG00000128191 ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC11781165__F3 Gut microbes and metabolites mediate various signaling pathways related to AP progression ENSG00000278718 ENSG00000112977 ENSG00000162711 ENSG00000167207 ENSG00000172936 ENSG00000145782 ENSG00000106100 ENSG00000057663 PMC8465798__F7 Ginsenoside Prolongs the Lifespan of C. elegans via Lipid Metabolism and Activating the Stress Response Signaling Pathway ENSG00000129347 ENSG00000173611 ENSG00000228474 PMC8581311__F7 Prolactin and endocrine therapy resistance in breast cancer: The next potential hope for breast cancer treatment ENSG00000065361 ENSG00000169047 ENSG00000146648 PMC7096357__F1 Co-regulation of Hippo and Hippo-like signaling pathways by Mob family proteins ENSG00000150457 ENSG00000112079 ENSG00000291442 ENSG00000115540 PMC10312956__F3 Networks of the rare-variant genes associated with suicidal behaviors in AI ENSG00000152661 ENSG00000116329 ENSG00000172345 ENSG00000117834 ENSG00000168661 ENSG00000128052 ENSG00000188404 ENSG00000204843 ENSG00000152804 ENSG00000174059 ENSG00000181195 ENSG00000124440 ENSG00000075213 PMC8581311__F4 Prolactin and endocrine therapy resistance in breast cancer: The next potential hope for breast cancer treatment ENSG00000157554 PMC8581311__F2 Prolactin and endocrine therapy resistance in breast cancer: The next potential hope for breast cancer treatment ENSG00000077782 ENSG00000146648 PMC3792737__F9 Summary of the interactions identified in this work between Dmrt5 and the secreted ligands and Wnt/Bmp regulated graded transcription factors expressed during early patterning of the cerebral cortex ENSG00000111249 ENSG00000170370 ENSG00000147862 ENSG00000106571 PMC12167289__F1 Schematic summary of signal transduction mechanism of the canonical Wnt signaling in human cells ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000102312 ENSG00000168036 PMC6732511__F2 Optimal management of atypical hemolytic uremic disease: challenges and solutions ENSG00000039537 ENSG00000203485 ENSG00000116785 ENSG00000244414 ENSG00000000971 ENSG00000122194 ENSG00000178726 ENSG00000292003 PMC6219741__F8 The proposed mechanisms of over-activation of UPR to trigger apoptosis ENSG00000143486 ENSG00000127663 ENSG00000128272 ENSG00000144895 ENSG00000162772 PMC7468622__F7 TRIM33 affecting renal cancer cell proliferation and EMT through the Wnt/Beta-catenin pathway (requires further experimental proof) ENSG00000170558 ENSG00000104228 ENSG00000168036 PMC5828294__F6 The metabolic changes in the liver of fed and fasted HrasG12S/+ mice.(a and b) Changes in gene expression in the liver of HrasG12S/+ mice under fed (a) and fasted (b) conditions ENSG00000125166 ENSG00000117054 ENSG00000065833 ENSG00000138029 ENSG00000115419 PMC5398560__F6 Complement Anaphylatoxins, C5a and C3a, Suppress Interferon-Beta Production in Response to Listeria monocytogenes by Inhibition of the Cyclic Dinucleotide-Activated Cytosolic Surveillance Pathway ENSG00000171855 ENSG00000183735 ENSG00000010671 PMC7970221__F1 Bioactive nanotherapeutic trends to combat triple negative breast cancer ENSG00000135446 ENSG00000105810 PMC3947439__F1 Molecular pathways regulated by PGE2 that are inhibited by aspirin ENSG00000291971 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000146648 ENSG00000196628 PMC8049958__F12 Hypothesis that autoimmune signaling pathways mediate the pronociceptive effects CRPS patient IgM in muMT fracture mice lacking immunoglobulin ENSG00000236625 PMC6797978__F6 Schematic representation of the effects of TAGLN2 on breast cancer metastasis ENSG00000087245 ENSG00000121966 PMC6815235__F1 Molecular mechanisms that underlies TRPV1-mediated nociceptive hypersensitivity in the dorsal root ganglion (DRG) neurons from a mouse model of sickle cell disease ENSG00000108691 ENSG00000170425 ENSG00000121807 ENSG00000168610 ENSG00000196689 PMC8603508__F1 Noncoding RNAs in Parkinson’s disease: biomarkers and associations with pathogenic pathways ENSG00000160710 ENSG00000128191 ENSG00000113360 PMC5548020__F2 Insulin signaling pathway ENSG00000171105 ENSG00000002330 ENSG00000005882 ENSG00000198793 ENSG00000158516 ENSG00000102977 ENSG00000026103 PMC5287062__F1 Cellular senescence ENSG00000149311 ENSG00000196712 PMC7706141__F8 PPI network of all DKKs and their similar genes ENSG00000152266 ENSG00000142192 ENSG00000109321 ENSG00000169744 ENSG00000168487 ENSG00000140092 ENSG00000150687 ENSG00000197702 ENSG00000145220 ENSG00000187513 ENSG00000281244 ENSG00000053747 ENSG00000117525 ENSG00000130052 ENSG00000157227 ENSG00000176435 ENSG00000078579 ENSG00000155011 ENSG00000050165 ENSG00000104371 ENSG00000175899 ENSG00000102312 ENSG00000170893 ENSG00000006327 PMC5714761__F3 Inhibition of stemness and EMT by IL-32θ ENSG00000168283 ENSG00000168610 PMC6534050__F5 Proposed model relating canonical and non-canonical Wnt signaling with teneurin-3 expression ENSG00000154342 ENSG00000168036 PMC11012151__F7 Exercise in Diabetic Nephropathy: Protective Effects and Molecular Mechanism ENSG00000169752 ENSG00000275031 PMC6796468__F5 Proposed model of PYCR1 interference on HCC cell proliferation and apoptosis ENSG00000169047 ENSG00000177606 PMC9094424__F1 Inborn Errors of the Immune System Associated With Atopy ENSG00000137033 ENSG00000237165 ENSG00000145777 ENSG00000134760 ENSG00000166090 ENSG00000143631 PMC9094424__F2 Inborn Errors of the Immune System Associated With Atopy ENSG00000291603 ENSG00000213658 ENSG00000168610 ENSG00000198286 PMC4124796__F1 Signaling pathways of leptin and insulin in the CNS ENSG00000171105 ENSG00000150907 ENSG00000115138 PMC8118521__F3 Transcriptional Profiling of Porcine HCC Xenografts Provides Insights Into Tumor Cell Microenvironment Signaling ENSG00000108691 ENSG00000198793 PMC3920940__F7 Diagram showing the model proposed for the association of EMT, CSCs and the PI3K/Akt/mTOR signaling pathway in CaP radioresistance and the effect of possible action of BEZ235 on radiosensitivity ENSG00000170558 ENSG00000198793 ENSG00000026508 PMC4816188__F1 TP53 pathway in CLL ENSG00000023445 ENSG00000149311 ENSG00000175054 ENSG00000115268 ENSG00000128513 PMC11012151__F2 Exercise in Diabetic Nephropathy: Protective Effects and Molecular Mechanism ENSG00000002330 ENSG00000158828 PMC5010719__F1 MET signaling pathway in IPF ENSG00000121879 PMC9180565__F2 Interplay between Mast Cells and Regulatory T Cells in Immune-Mediated Cholangiopathies ENSG00000196639 ENSG00000049768 ENSG00000105639 ENSG00000168610 PMC5867024__F2 Diagram showing the biased activation of CGRP receptors and AM1/2 receptors by ADM2, as well as the downstream signal pathway ENSG00000128165 ENSG00000132329 ENSG00000291507 ENSG00000131477 PMC9270311__F2 Effects of Ginsenosides on PI3K/AKT signaling pathway ENSG00000150907 ENSG00000113161 PMC8321873__F2 Metabolic Strategies for Inhibiting Cancer Development ENSG00000180210 ENSG00000131473 ENSG00000110711 PMC9270311__F3 Effects of Ginsenosides on PI3K/AKT signaling pathway ENSG00000132646 ENSG00000198793 ENSG00000171791 PMC3901108__F3 Summary diagram showing the role of ATG16L1 and NOD2 in the autophagy pathway and the defects observed when Crohn’s disease (CD) associated mutations are present ENSG00000167207 ENSG00000057663 PMC6189458__F2 Map of autophagy induction ENSG00000124102 ENSG00000177169 ENSG00000123395 ENSG00000152495 ENSG00000083290 ENSG00000126775 ENSG00000196455 ENSG00000023287 ENSG00000198793 PMC11480102__F11 Implications of ITCH-mediated ubiquitination of SIX1 on CDC27-cyclinB1 signaling in nasopharyngeal carcinoma ENSG00000134057 ENSG00000078747 ENSG00000004897 ENSG00000126778 PMC3957919__F7 Proposed model depicting the role of IFI35 in negative regulation of RIG-I signaling ENSG00000068079 ENSG00000088888 ENSG00000276561 PMC7877171__F3 Molecular mechanism by which intermittent fasting (IF) affects tumor cell growth ENSG00000019485 ENSG00000105835 ENSG00000142082 PMC1481658__F11 Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity ENSG00000115138 ENSG00000168610 PMC5587179__F2 Processing and digestion of engulfed apoptotic cells utilizes LC3-associated phagocytosis and promotes an anti-inflammatory response ENSG00000198382 ENSG00000145782 PMC5307356__F6 Untargeted metabolomics of colonic digests reveals kynurenine pathway metabolites, dityrosine and 3-dehydroxycarnitine as red versus white meat discriminating metabolites ENSG00000283060 ENSG00000125968 ENSG00000172201 PMC6738663__F2 HMGB1, as a priming signalling, involved in the stress-neuroinflammation-mesolimbic dopaminergic pathway ENSG00000162711 ENSG00000125538 ENSG00000189403 PMC4156316__F2 Molecular Mechanisms and Treatment of Radiation-Induced Lung Fibrosis ENSG00000168036 PMC6237563__F6 Schematic representation of the downstream targets of the MVA pathway, depicting its various intermediates (blue), end products (green) and functional implications (yellow) ENSG00000159224 ENSG00000197429 PMC3359833__F2 Linking pathways to disease: Crohn's disease (from Wang et al ENSG00000162594 ENSG00000096996 ENSG00000186810 ENSG00000138378 ENSG00000105397 ENSG00000168610 ENSG00000073861 ENSG00000112486 ENSG00000069667 ENSG00000115607 PMC3027010__F1 Schematic review of the molecular mechanisms linking diabetes mellitus and colorectal cancer ENSG00000134982 ENSG00000198793 PMC8790872__F7 Novel FBW7/NFAT1 axis regulates cancer immunity in sunitinib-resistant renal cancer by inducing PD-L1 expression ENSG00000129514 ENSG00000181555 PMC5029635__F14 NFKB functions as a molecular link between tumor cells and Th1/Tc1 T cells in the tumor microenvironment to exert radiation-mediated tumor suppression ENSG00000132906 ENSG00000108691 ENSG00000102871 ENSG00000168040 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC8640817__F1 Targeting ferroptosis for cancer therapy: iron metabolism and anticancer immunity ENSG00000167468 ENSG00000111684 PMC5793760__F4 TGFB signaling pathways ENSG00000170365 PMC11662157__F2 PI3K/mTOR signaling pathway during early T cell development ENSG00000167965 ENSG00000114315 ENSG00000121966 ENSG00000168685 PMC7299409__F5 miR-410-3p is induced by vemurafenib via ER stress and contributes to resistance to BRAF inhibitor in melanoma ENSG00000100811 ENSG00000167601 ENSG00000157764 ENSG00000123268 ENSG00000196712 PMC6090045__F1 Simplified general overview of glucose, fatty acid, and amino acid metabolism in healthy endothelial cells ENSG00000180210 ENSG00000070669 ENSG00000026103 PMC6771474__F2 Complement system and crosstalk with other innate immune effector systems in liver IRI, regeneration, and transplantation ENSG00000170458 ENSG00000125538 PMC6383147__F4 Positive feedback linking oxidative stress with enhanced p62 expression, Kelch-like ECH-associated protein 1 (KEAP-1) autophagic degradation, and stimulation of antioxidant enzyme expression ENSG00000177169 ENSG00000183735 ENSG00000178573 ENSG00000079999 PMC6311524__F1 The mitochondrial inner membrane protein MPV17 prevents uracil accumulation in mitochondrial DNA ENSG00000228716 ENSG00000065911 ENSG00000116984 PMC2729932__F2 ES-EB system has made possible the identification of multipotent progenitors for both hemato-vascular and cardio-vascular derivatives ENSG00000285109 ENSG00000183072 ENSG00000179348 ENSG00000016082 PMC9361353__F4 Prevaccination Glycan Markers of Response to an Influenza Vaccine Implicate the Complement Pathway ENSG00000039537 ENSG00000009724 ENSG00000113600 ENSG00000291559 ENSG00000166278 ENSG00000165471 PMC2763047__F3 Fibroblast Growth Factor Receptor Signaling Pathway as a Mediator of Intrinsic Resistance to EGFR-specific Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer ENSG00000109321 ENSG00000163235 ENSG00000124882 ENSG00000102678 ENSG00000146648 PMC11761653__F11 Seq2Hybrid recovers Ilamycin G BGC ENSG00000145020 ENSG00000062485 PMC2763047__F2 The Fibroblast Growth Factor Receptor Signaling Pathway in Non-Small Cell Lung Cancer ENSG00000019991 ENSG00000109321 ENSG00000163235 ENSG00000124882 ENSG00000102678 ENSG00000146648 ENSG00000140443 PMC7690341__F1 Pyrimidine nucleotide synthesis and chemical structure of PTC299 ENSG00000158825 ENSG00000094841 ENSG00000143179 ENSG00000084774 PMC4560835__F1 Recurrent 2,8-dihydroxyadenine nephropathy: a rare but preventable cause of renal allograft failure ENSG00000196839 ENSG00000291814 ENSG00000158125 PMC6313617__F1 Metabolism pathway of capecitabine and 5-fluorouracil (5-FU) ENSG00000228716 PMC8463266__F8 Novel compound FLZ alleviates rotenone-induced PD mouse model by suppressing TLR4/MyD88/NFKB pathway through microbiota–gut–brain axis ENSG00000172936 ENSG00000136869 PMC10887009__F4 MR suppresses gastric cancer development by inhibiting GSCSs ENSG00000172794 ENSG00000146648 ENSG00000057663 PMC4160635__F1 Genomic aberration of the proliferative and invasive pathways of glioma signalling ENSG00000138798 PMC4293489__F1 Activation of TLR4 by LPS ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC4293489__F2 Participation of CD14 in TLR4 signaling pathways triggered by sLPS and rLPS ENSG00000170458 ENSG00000172936 ENSG00000136869 PMC2919655__F3 Diversity in Post-Transcriptional Control of Neutrophil Chemoattractant Cytokine Gene Expression ENSG00000172936 ENSG00000175104 ENSG00000115594 ENSG00000163702 PMC4910912__F1 Union of active TF-miRNA regulatory pathway in CDDP resistance ENSG00000143799 ENSG00000105329 ENSG00000125148 ENSG00000073756 ENSG00000171345 ENSG00000158715 ENSG00000168003 ENSG00000245848 ENSG00000131914 ENSG00000108691 ENSG00000140379 ENSG00000115415 ENSG00000177606 ENSG00000171560 PMC9563287__F1 Richter Syndrome: From Molecular Pathogenesis to Druggable Targets ENSG00000148400 ENSG00000186716 ENSG00000197943 ENSG00000010671 PMC3967167__F1 Schematic drawing of the PI3K/Akt signaling pathway ENSG00000002330 PMC11214488__F8 GSK2334470 attenuates high salt-exacerbated rheumatoid arthritis progression by restoring Th17/Treg homeostasis ENSG00000140992 ENSG00000118515 ENSG00000159399 PMC5402284__F6 Transcriptome profiling of sulfate deprivation responses in two agarophytes Gracilaria changii and Gracilaria salicornia (Rhodophyta) ENSG00000145321 ENSG00000150787 PMC3967167__F5 PI3K/Akt-mediated mTOR activation positively regulates protein synthesis ENSG00000198793 PMC7465316__F2 Functional proteins association networks identified by differential proteomic analysis and relative Venn diagrams ENSG00000168028 ENSG00000090273 ENSG00000177600 ENSG00000176619 ENSG00000163631 PMC11711130__F6 SPC enhances Th9 cell differentiation and function by upregulating Smad3, STAT5, and Beta-catenin signaling pathways, mediated by increased mitochondrial ROS ENSG00000089692 ENSG00000163599 PMC5574319__F11 Signaling pathway changes triggered by HLJDD and its three principals ENSG00000124102 ENSG00000105227 PMC8151284__SF1 Attenuation of Oxidative Stress and Inflammatory Response by Chronic Cannabidiol Administration Is Associated with Improved n-6/n-3 PUFA Ratio in the White and Red Skeletal Muscle in a Rat Model of High-Fat Diet-Induced Obesity ENSG00000169047 ENSG00000026103 PMC8814716__F8 miR-154-5p Affects the TGFB1/Smad3 Pathway on the Fibrosis of Diabetic Kidney Disease via Binding E3 Ubiquitin Ligase Smurf1 ENSG00000105329 ENSG00000198742 PMC9481929__F8 Respiratory syncytial virus disrupts the airway epithelial barrier by decreasing cortactin and destabilizing F-actin ENSG00000168036 PMC11641539__F12 Diagram illustrates the neurotrophic activity of FVSE via activation of the Trk-B receptor in the Neurotrophin signaling pathway ENSG00000171791 PMC3310713__F3 Dual nature of Myc induced DDR ENSG00000149311 ENSG00000175054 ENSG00000136997 PMC9180978__F3 Soluble Epoxide Hydrolase and Diabetes Complications ENSG00000162711 ENSG00000128272 ENSG00000086991 ENSG00000162692 PMC3563272__F4 Eukaryotic Phospholipid Synthesis and Editing.G3P produced by GPDH is converted to PA by sequential acylation reactions regulated by GPAT and LPAAT ENSG00000173599 ENSG00000184207 PMC5590227__F1 The STAT3 pathway and therapeutic targets ENSG00000291971 ENSG00000138798 ENSG00000136997 ENSG00000105426 ENSG00000168610 ENSG00000146648 PMC7655627__F2 The mTOR pathway in liver cancer: from molecular genetics to targeted therapies ENSG00000157764 ENSG00000103064 ENSG00000136997 ENSG00000168036 ENSG00000121879 ENSG00000115419 PMC7655627__F1 The mTOR pathway in liver cancer: from molecular genetics to targeted therapies ENSG00000065911 ENSG00000155792 ENSG00000084774 PMC6584411__F7 Mechanism diagram ENSG00000087245 ENSG00000135446 ENSG00000170558 ENSG00000123374 ENSG00000105810 ENSG00000100985 PMC7937231__F10 Bacterial invasion of epithelial cells pathway (KEGG ID: hsa05100) in the CoNS vs ENSG00000110395 ENSG00000241553 ENSG00000106299 ENSG00000141367 PMC3407530__F5 A simplified model for p80HT targeting the IL-10-Stat3 signaling pathway to promote plasma cell expansion and tumor development ENSG00000105397 ENSG00000118971 ENSG00000168610 PMC8745127__F2 Altered Mitochondrial Metabolism in Thyroid Cancer Development and Mitochondria-Targeted Thyroid Cancer Treatment ENSG00000203485 ENSG00000116688 ENSG00000158828 ENSG00000171109 ENSG00000214253 PMC9585222__F7 Improvement of gut-vascular barrier by terlipressin reduces bacterial translocation and remote organ injuries in gut-derived sepsis ENSG00000168036 PMC8073943__F5 EPHA3 Contributes to Epigenetic Suppression of PTEN in Radioresistant Head and Neck Cancer PMC4287801__F1 Molecular pathogenesis and therapeutics of Marfan syndrome (MFS) ENSG00000042832 ENSG00000135341 ENSG00000166147 PMC3160745__F1 PI-3K/Akt signaling pathway ENSG00000002330 ENSG00000169047 ENSG00000198793 PMC11354507__F1 SARS-CoV-2 entry, mitochondrial damage sensing and innate immune dysregulation ENSG00000162711 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000130234 ENSG00000158828 ENSG00000184012 ENSG00000131323 ENSG00000198925 PMC11354507__F2 Inflammation triggered by macrophage after SARS-CoV-2 infection ENSG00000174125 ENSG00000213928 ENSG00000168610 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000130234 ENSG00000187554 ENSG00000184012 ENSG00000172936 ENSG00000131323 ENSG00000175104 PMC11809390__F8 Constitutive DRD4 activates TGF‐B receptors independent of ligands to promote CRC metastasis ENSG00000276825 ENSG00000170365 ENSG00000124216 ENSG00000120693 ENSG00000204217 PMC5779628__F11 Excitation–transcription coupling responsible for maladaptive metabolic and antioxidant remodeling in HF ENSG00000156026 ENSG00000198626 ENSG00000112992 ENSG00000132170 ENSG00000106459 PMC6444160__F6 Networks of Ingenuity Canonical Pathways results of mRNA of APP/PS1 and SAMP8 mice brain tissues ENSG00000145632 ENSG00000151725 ENSG00000120820 ENSG00000108551 ENSG00000054654 ENSG00000137801 ENSG00000276876 ENSG00000105894 ENSG00000112242 ENSG00000078900 ENSG00000172031 ENSG00000140455 ENSG00000138162 ENSG00000177519 ENSG00000099204 ENSG00000182742 ENSG00000111262 ENSG00000143546 ENSG00000115163 ENSG00000164761 ENSG00000088305 ENSG00000189056 ENSG00000134363 ENSG00000143458 ENSG00000150551 ENSG00000178718 ENSG00000260027 ENSG00000291663 ENSG00000167767 ENSG00000118785 ENSG00000135638 ENSG00000065029 ENSG00000144857 ENSG00000132205 ENSG00000106772 ENSG00000026508 ENSG00000108511 ENSG00000120075 ENSG00000181195 ENSG00000292254 ENSG00000106078 PMC3242418__F1 HER 2: Biology, Detection, and Clinical Implications ENSG00000113905 ENSG00000163235 ENSG00000138798 PMC3471161__F1 VEGF pathway and the site of action of the inhibitors ENSG00000112715 ENSG00000150630 PMC3964016__F1 Cl− channels and proposed functions in vascular smooth muscle cells ENSG00000102189 ENSG00000016490 ENSG00000001626 PMC6320922__F1 Drosophila Jak/STAT signaling components and the corresponding human homologs and their protein families ENSG00000084093 ENSG00000291971 ENSG00000146247 ENSG00000033800 ENSG00000221869 ENSG00000168610 ENSG00000245848 ENSG00000138378 ENSG00000171150 ENSG00000115415 ENSG00000173757 ENSG00000171634 ENSG00000064655 ENSG00000165288 PMC8163803__F6 Transcriptome analysis of MBD5-associated neurodevelopmental disorder (MAND) neural progenitor cells reveals dysregulation of autism-associated genes ENSG00000143942 ENSG00000176165 ENSG00000204406 PMC4381506__F2 Transcript abundance of genes related to central metabolic pathways under different conditions in K ENSG00000110711 ENSG00000185591 ENSG00000167900 PMC4838297__F6 Diminished COX-2/PGE2-Mediated Antiviral Response Due to Impaired NOX/MAPK Signaling in G6PD-Knockdown Lung Epithelial Cells ENSG00000102871 ENSG00000127191 PMC3416387__F5 Proposed metabolic pathways for central carbon and nitrogen metabolism in Y88 during glucose growth, based on protein identifications (dark gray ovals) and the presence of their corresponding genes in the Y88 genome ENSG00000122966 ENSG00000117118 ENSG00000172005 ENSG00000150787 ENSG00000155438 PMC9332298__F2 PNPLA1-Mediated Acylceramide Biosynthesis and Autosomal Recessive Congenital Ichthyosis ENSG00000118402 ENSG00000151726 ENSG00000171954 ENSG00000042832 ENSG00000011198 ENSG00000154227 ENSG00000066322 ENSG00000119537 ENSG00000062282 PMC2537575__F5 NFKB canonical signaling pathway from IPA ENSG00000104856 ENSG00000226275 ENSG00000291603 ENSG00000163235 ENSG00000138798 ENSG00000173039 ENSG00000197943 ENSG00000150455 ENSG00000127191 PMC7657020__F3 Predicted interaction map of SARS-CoV-2 proteins and top 20 host proteins associated with cytokine signaling pathway and Neutrophils degranulation ENSG00000051523 ENSG00000091317 ENSG00000169896 ENSG00000109320 ENSG00000291971 ENSG00000138798 ENSG00000173039 ENSG00000137845 ENSG00000118640 ENSG00000168610 ENSG00000185883 ENSG00000291507 ENSG00000150991 ENSG00000127481 ENSG00000148175 ENSG00000112697 ENSG00000146648 PMC3817742__F7 ABCB10 and heme synthesis pathway ENSG00000135776 ENSG00000158578 PMC4068075__F3 Consequences of EMT on innate signaling ENSG00000136807 ENSG00000056558 ENSG00000173039 ENSG00000131323 PMC7549355__F1 Hypoxia-inducible factor (HIF) and examples of long non-coding RNA (lncRNA) involvement ENSG00000134086 PMC6413748__F3 Synthesis pathway of cardiolipin from lysophosphatidylcholine and lysophosphatidic acid ENSG00000184207 ENSG00000110536 PMC5023675__F1 TNF-Alpha-activated canonical nuclear factor kappa-light-chain-enhancer of activated B cells (NFKB) signaling pathway ENSG00000102871 ENSG00000127191 PMC4957230__F4 Transcriptome sequencing wide functional analysis of human mesenchymal stem cells in response to TLR4 ligand ENSG00000108702 ENSG00000169248 ENSG00000162711 ENSG00000050730 ENSG00000185215 ENSG00000187608 ENSG00000056972 ENSG00000124875 ENSG00000131669 ENSG00000095739 ENSG00000164400 ENSG00000128342 ENSG00000090376 ENSG00000259207 ENSG00000185022 ENSG00000115267 ENSG00000007908 ENSG00000184979 ENSG00000169245 ENSG00000108691 ENSG00000144749 ENSG00000118785 ENSG00000127124 ENSG00000134070 ENSG00000184371 ENSG00000121577 ENSG00000121060 ENSG00000198355 PMC9241180__F7 circFBXO7/miR-96-5p/MTSS1 axis is an important regulator in the Wnt signaling pathway in ovarian cancer ENSG00000168036 PMC10378150__F1 STAT3 deficiency prevents GVHD in target organs while preserving GVL activity in lymphohematopoietic tissues ENSG00000136997 ENSG00000168610 PMC7550743__F3 Amino acid metabolism regulates PDAC progression ENSG00000125166 ENSG00000065833 ENSG00000284774 ENSG00000151012 ENSG00000104783 ENSG00000198793 ENSG00000094755 ENSG00000070669 PMC2815894__F2 Network of ABA-induced stomatal closure ENSG00000173599 ENSG00000145321 PMC10447124__F8 Mapping of Rap1 signaling pathway in NI vs ENSG00000213658 ENSG00000130396 ENSG00000163207 ENSG00000291971 ENSG00000102312 ENSG00000185269 ENSG00000087460 PMC7073900__F1 Key hallmarks of the ferroptotic pathway of cell death ENSG00000161905 ENSG00000167468 PMC8653577__F2 Maturing heart muscle cells: Mechanisms and transcriptomic insights ENSG00000198793 ENSG00000178568 PMC2940871__F3 Metabolic reactions involving the PGM2 (adapted from ) ENSG00000197713 ENSG00000169299 ENSG00000047597 ENSG00000158125 PMC7988757__F5 Hypoxia-induced inhibition of mTORC1 activity in the developing lung: a possible mechanism for the developmental programming of pulmonary hypertension ENSG00000136158 ENSG00000070193 PMC8370908__F3 Alteration of protein expression and spliceosome pathway activity during Barrett’s carcinogenesis ENSG00000125755 ENSG00000110107 ENSG00000109606 ENSG00000172005 ENSG00000179950 ENSG00000138668 ENSG00000101343 ENSG00000132792 ENSG00000126698 ENSG00000285049 ENSG00000087087 PMC7652990__F2 Network of pathways involved in respiration, ethylene biosynthesis, and signaling, and ROS production and signaling during the ripening process ENSG00000136997 ENSG00000116984 PMC5023675__F5 Non-canonical NFKB signaling pathway ENSG00000104856 ENSG00000127191 PMC9188076__F5 Pharmacological mechanisms of sodium-glucose co-transporter 2 inhibitors in heart failure with preserved ejection fraction ENSG00000173599 PMC9037237__F5 Supplementation of Specific Collagen Peptides Following High-Load Resistance Exercise Upregulates Gene Expression in Pathways Involved in Skeletal Muscle Signal Transduction ENSG00000145604 ENSG00000104365 ENSG00000107404 ENSG00000157764 ENSG00000106070 ENSG00000198793 ENSG00000052795 ENSG00000118515 ENSG00000155792 ENSG00000213341 ENSG00000285069 PMC9037237__F6 Supplementation of Specific Collagen Peptides Following High-Load Resistance Exercise Upregulates Gene Expression in Pathways Involved in Skeletal Muscle Signal Transduction ENSG00000142192 ENSG00000101474 ENSG00000070831 ENSG00000109320 ENSG00000102871 ENSG00000130522 ENSG00000115904 ENSG00000213341 ENSG00000130159 ENSG00000169032 ENSG00000127191 ENSG00000081189 ENSG00000128272 ENSG00000136997 ENSG00000026103 ENSG00000158050 PMC10887079__F1 Nrf2 signaling pathway ENSG00000100387 ENSG00000079999 PMC9289362__F1 Factors Affecting the Expression of Recombinant Protein and Improvement Strategies in Chinese Hamster Ovary Cells PMC4606185__F1 Wnt/Beta-catenin signaling pathway in high glucose condition ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3579516__F7 Alliance for Cellular Signaling Plasmid Collection ENSG00000130413 ENSG00000145632 ENSG00000008710 ENSG00000114124 ENSG00000172680 ENSG00000147613 ENSG00000157404 ENSG00000146872 ENSG00000123572 ENSG00000138071 ENSG00000072195 ENSG00000276876 ENSG00000183943 ENSG00000168404 ENSG00000163788 ENSG00000162889 ENSG00000154358 ENSG00000125388 ENSG00000145348 ENSG00000111816 ENSG00000127334 ENSG00000142149 ENSG00000173846 ENSG00000135605 ENSG00000007047 ENSG00000277273 ENSG00000062524 ENSG00000120539 ENSG00000038382 ENSG00000065613 ENSG00000182511 ENSG00000128052 ENSG00000113263 ENSG00000160447 ENSG00000147044 ENSG00000171105 ENSG00000124610 ENSG00000150457 ENSG00000086015 ENSG00000165238 ENSG00000149311 ENSG00000160867 ENSG00000142731 ENSG00000135828 ENSG00000168038 ENSG00000116649 ENSG00000136021 ENSG00000204217 ENSG00000185189 PMC9037237__F4 Supplementation of Specific Collagen Peptides Following High-Load Resistance Exercise Upregulates Gene Expression in Pathways Involved in Skeletal Muscle Signal Transduction ENSG00000141349 ENSG00000002330 ENSG00000179091 ENSG00000105401 ENSG00000214827 ENSG00000108342 ENSG00000213341 ENSG00000167965 ENSG00000171791 ENSG00000177455 ENSG00000136997 ENSG00000143322 ENSG00000136869 ENSG00000127948 PMC11597624__F1 Secondary metabolites in invasive weeds, for the synthesis of isopentenyl diphosphate (IPP), dimethylallyl diphosphate (DMAPP), methylerythritol phosphate (MEP), and mevalonate (MVA) pathways responsible ENSG00000197429 ENSG00000167508 PMC6121366__F6 KEGG and BioCarta pathways of proteins encoded by genes related to cell cycle and ROS whose expression was altered in BS-24-1 cells after treatment with ethyl acetate extract of A ENSG00000132906 ENSG00000205250 ENSG00000277273 ENSG00000164305 ENSG00000102172 ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000132646 ENSG00000136997 ENSG00000123374 ENSG00000164754 ENSG00000112378 ENSG00000026103 PMC6881718__F6 Cellular context of TLR5 engagement by UPEC FliC in the bladder leading to early IL-10 induction ENSG00000174125 ENSG00000168040 ENSG00000150455 ENSG00000276561 ENSG00000143387 ENSG00000183735 ENSG00000239732 ENSG00000115415 ENSG00000170458 ENSG00000187554 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000064012 ENSG00000184216 ENSG00000164342 PMC3185786__F1 Survival pathways controlled by Tax ENSG00000173039 PMC4396490__F10 Caspase-1–mediated pathway promotes generation of thromboinflammatory microparticles ENSG00000125538 ENSG00000089041 PMC7590701__F6 Network analysis and hypothetical model construction ENSG00000066468 ENSG00000159216 ENSG00000143768 ENSG00000166086 ENSG00000284571 ENSG00000026508 ENSG00000168610 ENSG00000136826 PMC8812184__F8 RNA-seq of nine canine prostate cancer cell lines reveals diverse therapeutic target signatures ENSG00000002330 ENSG00000291971 ENSG00000123374 ENSG00000171791 ENSG00000146648 ENSG00000167034 ENSG00000115419 ENSG00000104368 PMC7017262__F2 Molecular H ENSG00000108830 ENSG00000065361 ENSG00000113070 ENSG00000163914 ENSG00000160293 ENSG00000146648 PMC6164133__F1 Intracellular signalling pathways of vitamin A ENSG00000138207 ENSG00000291971 PMC7569467__F1 Schematic graph demonstrates the role of glial cells and the relevant signaling pathway ENSG00000162711 ENSG00000136869 PMC3083931__F1 Canonical and noncanonical nuclear factorKB (NFKB) activation pathways ENSG00000104856 ENSG00000123091 ENSG00000078747 ENSG00000173039 ENSG00000111321 PMC9123888__F6 Possible mechanisms of the effect of melatonin in HDP cells ENSG00000134640 ENSG00000168412 ENSG00000168036 PMC9456295__F2 Norepinephrine, beyond the Synapse: Coordinating Epigenetic Codes for Memory ENSG00000198793 ENSG00000167658 PMC4374983__F2 Serum response factor pathway in myelopoiesis and myelodysplasia with 5q abnormality ENSG00000170458 ENSG00000044115 ENSG00000136869 PMC4374983__F1 Serum response factor pathway ENSG00000105298 PMC2666387__F7 Proposed Src involvement in HCEC wound healing ENSG00000291971 ENSG00000113070 ENSG00000146648 PMC8750386__F8 Peroxiredoxin 6 Applied after Exposure Attenuates Damaging Effects of X-ray Radiation in 3T3 Mouse Fibroblasts ENSG00000149311 ENSG00000123374 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000139687 ENSG00000138385 PMC8234963__F6 Protective Effect of Piplartine against LPS-Induced Sepsis through Attenuating the MAPKs/NFKB Signaling Pathway and NLRP3 Inflammasome Activation ENSG00000162711 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC3632588__F6 Mutant p53 Attenuates the Anti-Tumorigenic Activity of Fibroblasts-Secreted Interferon Beta ENSG00000115415 PMC8835057__F8 Cytokine Receptors—Regulators of Antimycobacterial Immune Response ENSG00000105397 ENSG00000168610 PMC8835057__F9 Cytokine Receptors—Regulators of Antimycobacterial Immune Response ENSG00000105397 ENSG00000115415 ENSG00000168610 PMC8835057__F6 Cytokine Receptors—Regulators of Antimycobacterial Immune Response ENSG00000162594 ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000168610 PMC8835057__F7 Cytokine Receptors—Regulators of Antimycobacterial Immune Response ENSG00000115415 PMC7725871__F2 TLR4 signaling pathway: TLR4 is localized on the cell surface for ligand recognition, some of which are recognized after TLR4 interacting with MD2, even requiring CD14 and/or LBP involvement ENSG00000170458 ENSG00000198793 ENSG00000189403 ENSG00000172936 ENSG00000136869 PMC4011959__F3 The initial stages of vesicle elongation in macroautophagy ENSG00000152348 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC6032341__F3 ATM-dependent DNA Damage Response ENSG00000149311 ENSG00000010017 ENSG00000172977 PMC8674037__F6 Activation of AdipoR1 with rCTRP9 Preserves BBB Integrity through the APPL1/AMPK/Nrf2 Signaling Pathway in ICH Mice ENSG00000178573 ENSG00000100387 ENSG00000159346 ENSG00000079999 PMC4166552__F9 Model of cooperation of PLCB3 in the P.aeruginosa-dependent signaling in bronchial epithelial cells ENSG00000187554 ENSG00000149782 ENSG00000172936 PMC6174755__F3 Exosomes can regenerate stem cell phenotypes and convert them to CSCs by regulating the Wnt pathway ENSG00000156076 ENSG00000137673 ENSG00000134982 PMC5824910__F1 G-alpha signaling pathway in uveal melanoma ENSG00000038382 ENSG00000126016 ENSG00000198793 ENSG00000163914 PMC2946515__F3 Mutant epidermal growth factor receptor, EGFRvIII, promotes cell survival and proliferation by preferential signaling through the phosphotidyinositol-3-kinase (PI3K) pathway ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC2785881__F3 Sialic Acid Utilisation and Synthesis in the Neonatal Rat Revisited ENSG00000159921 ENSG00000170191 ENSG00000135838 ENSG00000111726 ENSG00000164414 ENSG00000147162 ENSG00000124357 ENSG00000119899 ENSG00000117620 ENSG00000102032 ENSG00000095380 ENSG00000013375 PMC6487163__F1 Process and regulatory mechanism of autophagy ENSG00000177169 ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC11487528__F2 COL10A1 regulates EMT, tumor cell proliferation and metastasis by phosphorylating Smad in conjunction with DDR2 and activating the TGFB signaling pathway ENSG00000087245 ENSG00000162733 ENSG00000125398 ENSG00000170558 ENSG00000100985 PMC11487528__F3 COL10A1 activates signaling pathways and regulates gene expression ENSG00000162733 ENSG00000170558 ENSG00000165819 PMC6488374__F3 Molecular mechanisms that regulate quiescence and activation of McSCs niche in telogen and anagen, respectively ENSG00000281324 ENSG00000147862 ENSG00000065618 ENSG00000162337 ENSG00000050165 ENSG00000168036 ENSG00000114315 ENSG00000127129 PMC7059124__F1 Schematic illustration of the autophagic pathway ENSG00000177169 ENSG00000152348 ENSG00000198382 ENSG00000083290 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC7182350__F1 Rac GTPase activity is regulated by synaptic activation through synaptic receptors that are known to be involved in memory formation such as NMDA, Trk, and Eph receptors ENSG00000156299 ENSG00000116106 ENSG00000138443 ENSG00000288461 ENSG00000133216 PMC7059124__F4 Hepatotropic oncogenic viruses and their impact on autophagy regulation ENSG00000177169 ENSG00000198382 ENSG00000107338 ENSG00000083290 ENSG00000198793 ENSG00000144848 ENSG00000096717 ENSG00000145782 ENSG00000057663 PMC2311419__F1 P. gingivalis accelerates gingival epithelial cell progression through the cell cycle PMC11487528__F4 COL10A1 in malignant tumors ENSG00000162733 ENSG00000138795 ENSG00000125398 ENSG00000163032 ENSG00000170558 ENSG00000253352 ENSG00000078098 ENSG00000165819 PMC6585451__F2 Gut mycobiota in immunity and inflammatory disease ENSG00000112116 ENSG00000198793 ENSG00000184371 PMC8495217__F3 Different View for an Old Disease: NEDDylation and Other Ubiquitin-Like Post-Translational Modifications in Chronic Lymphocytic Leukemia ENSG00000285246 ENSG00000127191 PMC9241412__F2 Regulatory role of Pin1 in neuronal death ENSG00000127445 PMC9120690__F1 Targeting O-GlcNAcylation in ischemic stroke ENSG00000100522 ENSG00000198408 ENSG00000100219 ENSG00000013375 PMC3918861__F2 Induction of apoptosis ENSG00000002330 ENSG00000102871 ENSG00000168040 ENSG00000026103 PMC3928706__F1 Mechanism underlying GD T cell killing of tumours: GD T cell receptor (TCR) interacts with isopentenyl pyrophosphate (IPP) generated through the mevalonate pathway in tumours ENSG00000197429 ENSG00000231179 ENSG00000204520 PMC12230168__F7 Molecular mechanism of rosmarinic acid synergistically enhancing gefitinib efficacy in EGFR-mutant lung cancer by inhibiting cancer-stromal interactions and miR-21 signaling pathway ENSG00000078098 PMC8073623__F1 New Insights into YES-Associated Protein Signaling Pathways in Hematological Malignancies: Diagnostic and Therapeutic Challenges ENSG00000150457 ENSG00000131023 PMC9469021__F10 Immunosuppression and apoptosis activation mediated by p53-Bcl2/Bax signaling pathway -The potential mechanism of goldfish (Carassius auratus Linnaeus) gill disease caused by Myxobolus ampullicapsulatus ENSG00000064601 ENSG00000111537 ENSG00000125538 PMC9469021__F11 Immunosuppression and apoptosis activation mediated by p53-Bcl2/Bax signaling pathway -The potential mechanism of goldfish (Carassius auratus Linnaeus) gill disease caused by Myxobolus ampullicapsulatus ENSG00000132906 ENSG00000291983 ENSG00000104689 ENSG00000002330 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000171791 ENSG00000168040 ENSG00000064012 ENSG00000164305 PMC4661094__F1 RPE Necroptosis in Response to Oxidative Stress and in AMD ENSG00000102871 ENSG00000168040 ENSG00000104081 PMC3118263__F4 Pathway analysis links the differentially expressed gene signatures of the MED29 transduced Hs 700T and MIAPaCa-2 cells to a cellular network involved in cell cycle, cancer, and genetic disorder ENSG00000072571 ENSG00000115163 ENSG00000178999 ENSG00000175756 ENSG00000123485 ENSG00000102471 ENSG00000087586 ENSG00000134690 ENSG00000116977 PMC1603666__F9 Erk- and PI3K-Akt-dependent cascades regulating mTOR signaling ENSG00000138798 ENSG00000198793 PMC11688305__F1 The structural comparison and similarities between CD4 and LAG-3 ENSG00000089692 ENSG00000134982 ENSG00000137845 PMC4661094__F2 RPE Necroptosis in Response to Oxidative Stress and in AMD ENSG00000102871 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC7098936__F1 Drugs in development for the treatment of achondroplasia ENSG00000173786 PMC6880832__F7 Schematic illustration of miR-4666-3p and miR-329 are both low expressed in non-QCCSCs and synergistically regulate TGFB/Smad pathway PMC6563192__F7 DEGs that are located in the neighborhood (putative cis-targets) of DELs and that are associated with Notch signaling pathway and stress granule formation ENSG00000144895 ENSG00000273529 ENSG00000133961 ENSG00000114315 PMC3983496__F2 The proposed intracellular signaling pathways regulated by Cx43 hemichannels in bone cells ENSG00000152266 ENSG00000002330 ENSG00000291971 ENSG00000168036 ENSG00000065802 PMC219483__F1 Biochemical pathways of TSH and folate metabolism in Leishmania ENSG00000228716 ENSG00000136877 PMC11855067__F3 Core genes of key signaling pathway map of tectoridin against ischemic stroke ENSG00000177455 ENSG00000103479 ENSG00000065833 ENSG00000101146 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000169047 ENSG00000104894 PMC8024517__F1 Proposed mechanisms by which innate immune responses not only induce inflammation but also skew emerging adaptive immune responses towards a response that amplifies myeloid cell activation in mycobacterial IRIS or COVID-19 ENSG00000169245 ENSG00000108691 ENSG00000125538 PMC5831775__F2 Simplified scheme of the cilia-mediated HH signal transduction pathway in vertebrates ENSG00000166813 ENSG00000128602 PMC3464365__F1 Linking cellular metabolism with the circadian clock transcriptional complex ENSG00000105835 ENSG00000171720 ENSG00000096717 PMC8991826__F9 TIM-1 promotes proliferation and metastasis, and inhibits apoptosis, in cervical cancer through the PI3K/AKT/p53 pathway ENSG00000170558 ENSG00000198793 PMC7278240__F3 Brain oxytocin: how puzzle stones from animal studies translate into psychiatry ENSG00000164129 ENSG00000187688 ENSG00000167658 ENSG00000146648 PMC4989114__F10 Coelimination and Survival in Gene Network Evolution: Dismantling the RA-Signaling in a Chordate ENSG00000121039 ENSG00000135697 PMC9694413__F3 Biodegradation and Metabolic Pathway of the Neonicotinoid Insecticide Thiamethoxam by Labrys portucalensis F11 ENSG00000125827 ENSG00000213593 ENSG00000166479 PMC7116063__F7 Signal integration in the (m)TORC1 growth pathway ENSG00000177058 ENSG00000141458 ENSG00000239282 ENSG00000274145 ENSG00000285069 PMC8714756__F5 Adaptation Strategies to Improve the Resistance of Oilseed Crops to Heat Stress Under a Changing Climate: An Overview ENSG00000108798 ENSG00000163788 PMC6834478__F2 Mouse models used to study the PI3K/AKT/mTOR axis in PCa ENSG00000101407 ENSG00000155792 ENSG00000140464 PMC7236745__F3 NF-kB/E2F/Rb and p53/p21 pathways by proteasome.NF-kB/E2F/Rb pathway: under unstimulated conditions, NF-kB is kept inactive in the cytosol by IkB inhibitor ENSG00000134057 ENSG00000152669 ENSG00000134982 ENSG00000132646 ENSG00000123374 PMC7116063__F1 Signal integration in the (m)TORC1 growth pathway ENSG00000239282 ENSG00000285069 PMC6614068__F6 Quantitative Proteomic Analysis Reveals Impaired Axonal Guidance Signaling in Human Postmortem Brain Tissues of Chronic Traumatic Encephalopathy PMC5301350__F7 Differentially expressed genes (DEGs) in photosynthesis pathway in different combinations ENSG00000173599 PMC6636296__F1 metabolic pathways in cancer cells ENSG00000198793 ENSG00000168036 PMC6636296__F2 Network of Wnt signaling regulates tumor metabolism reprogramming ENSG00000134982 ENSG00000198793 ENSG00000136997 ENSG00000168036 PMC6142822__F3 Gut-brain communicates with the brain mainly via three pathways of the microbiota–gut–brain axis ENSG00000163235 PMC6535379__F1 Signaling pathways involved on induction of endoplasmic reticulum (ER) stress ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC4162005__F1 Model for regulation of expression/activity of multiple P450s by AKR1D1 ENSG00000180432 ENSG00000099377 ENSG00000135929 PMC7573490__F4 Interaction of Leptospira interrogans with the innate immune system ENSG00000174125 ENSG00000162711 ENSG00000167207 ENSG00000187554 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000106100 PMC4014576__F6 Protein Tyrosine Phosphatases PTP-1B, SHP-2, and PTEN Facilitate Rb/E2F-Associated Apoptotic Signaling ENSG00000064012 ENSG00000164305 PMC8931761__F1 Traditional Chinese Medicines as Effective Reversals of Epithelial-Mesenchymal Transition Induced-Metastasis of Colorectal Cancer: Molecular Targets and Mechanisms ENSG00000152266 ENSG00000169554 ENSG00000170558 ENSG00000198793 ENSG00000168036 PMC7234920__F2 The compartmentalization and interplay between the extracellular and intracellular pathways for (acyl-)CoA degradation and intracellular CoA synthesis ENSG00000152782 ENSG00000273494 ENSG00000167799 ENSG00000138621 ENSG00000101473 ENSG00000130810 ENSG00000127125 ENSG00000112303 ENSG00000140876 ENSG00000213965 ENSG00000120137 ENSG00000068120 ENSG00000112299 ENSG00000100372 PMC8377541__F8 CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/Beta-Catenin Signaling Pathway in Glioma ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000203710 ENSG00000165879 ENSG00000168036 ENSG00000168646 ENSG00000117322 ENSG00000196628 PMC5445305__F7 Characterization of central metabolic model in developing L ENSG00000159224 ENSG00000197713 ENSG00000108515 ENSG00000173599 ENSG00000172005 ENSG00000198670 PMC6936734__F1 Schematic representation of sphingosine-1-phosphate (S1P) pathway ENSG00000063176 ENSG00000183018 ENSG00000102172 PMC12072856__F1 Bacteria antagonize p53 protein by mechanisms of its destabilization or by reducing expression of its mRNA ENSG00000136869 ENSG00000146648 PMC4753639__F8 Targeting Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer by Inducing Epidermal Growth Factor Receptor Degradation via Methionine 790 Oxidation ENSG00000015285 ENSG00000285250 ENSG00000074771 ENSG00000146648 PMC6629768__F1 Some examples of lncRNA mechanisms that unfold in the cytoplasmic compartment ENSG00000177169 ENSG00000156171 PMC2952341__F1 Alteration of Notch signaling in skeletal development and disease ENSG00000138795 ENSG00000143801 ENSG00000168214 ENSG00000128917 ENSG00000171462 ENSG00000184916 ENSG00000114315 ENSG00000090932 PMC9370431__F5 Effect of Laminaria japonica on Metabolic Syndrome: A Systematic Review of Its Efficacy and Mechanism of Action ENSG00000026103 PMC9312335__F4 High-Temperature Stress Effect on the Red Cusk-Eel (Geypterus chilensis) Liver: Transcriptional Modulation and Oxidative Stress Damage ENSG00000291983 ENSG00000128272 ENSG00000171791 ENSG00000198168 PMC11995091__F2 Sketch represents the impact of nano-encapsulated tea polyphenols impact poultry health ENSG00000167468 ENSG00000172936 ENSG00000136869 PMC9370431__F4 Effect of Laminaria japonica on Metabolic Syndrome: A Systematic Review of Its Efficacy and Mechanism of Action ENSG00000125538 ENSG00000162692 PMC10672284__F1 Multifaceted functions of (AMPs): (A) Depiction of the signaling pathway involved in Gram-negative bacteria-induced infection caused by lipopolysaccharides (LPS) ENSG00000172936 ENSG00000150455 PMC10670481__F6 Analysis of KEGG pathway and interactive enrichment networks ENSG00000180210 ENSG00000159224 ENSG00000122966 ENSG00000126457 ENSG00000100504 ENSG00000160741 PMC2856448__F1 Opposing influences on Foxo cellular localization and transcriptional activity ENSG00000147162 ENSG00000126457 ENSG00000096717 PMC11674267__F1 Mechanistic pathway of methuosis-induced vacuolization ENSG00000115020 PMC11674267__F3 Schematic summary of alkaliptosis pathway induced by JTC801, a pH-dependent form of cell death ENSG00000159720 ENSG00000189403 ENSG00000168610 PMC5872768__F1 Possible routes of lipid oversupply-induced insulin resistances associated with mitochondrial and endoplasmic reticulum (ER) stress ENSG00000119737 ENSG00000116688 ENSG00000169047 ENSG00000171109 PMC11674267__F4 How SNG induces oxeiptosis in colorectal cancer cells based on [20] ENSG00000156709 ENSG00000247077 PMC7465688__F1 Postulated signaling pathways affecting endothelial progenitor cells (EPCs) ENSG00000138798 ENSG00000121966 PMC5345629__F5 Validation and interaction networks of the differentially expressed miRNAs PMC7156293__F3 The MyD88‐dependent and MyD88‐independent pathways mediated by TLR4 ligation to induce NF‐KB activation and cytokine gene expression ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000073756 ENSG00000184216 PMC8892735__F4 Long and short non-coding RNAs modulating EZH2 signaling in cancer ENSG00000100811 ENSG00000112242 ENSG00000135100 ENSG00000157227 ENSG00000174744 ENSG00000124766 ENSG00000121966 ENSG00000159399 PMC2810075__F6 CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts ENSG00000163464 ENSG00000168036 ENSG00000168040 ENSG00000026103 PMC3698571__F2 Advances in targeting cell surface signalling molecules for immune modulation ENSG00000139193 ENSG00000089692 ENSG00000134982 PMC11844401__F1 Four-step protopathway (highlighted in lilac) restores growth of ΔpdxB E ENSG00000291814 ENSG00000139515 PMC6562762__F8 Hypothetical model of Se homeostasis in brain ENSG00000183291 ENSG00000167468 ENSG00000250722 ENSG00000178980 PMC7254712__F4 Graph of the ECM–receptor interaction pathway (17) ENSG00000136457 ENSG00000135218 ENSG00000168743 ENSG00000110799 ENSG00000026508 PMC8892735__F1 Long and short non-coding RNAs modulating EZH2 signaling in cancer ENSG00000074266 ENSG00000178691 PMC3368236__F5 Sema3E-PlexD1 signaling regulates pathway-specific synapse formation in the striatum ENSG00000170381 ENSG00000184845 PMC8305917__F3 The Actin Cytoskeleton via Rho GTPase Signalling in Dictyostelium and Mammalian Cells: A Parallel Slalom ENSG00000140575 PMC3135645__F1 Coordinated regulation of p53, target of rapamycin (TOR), and insulin/insulin-like growth factor 1 (IGF-1) pathways PMC10304713__F2 SARS-CoV-2 employs different mechanisms to activate the host’s innate immune system ENSG00000213928 ENSG00000088888 ENSG00000172936 ENSG00000162924 ENSG00000175104 ENSG00000121060 ENSG00000184216 PMC3031055__F3 TFM-C-induced alteration to IL-12p40 chaperone interactions ENSG00000136986 ENSG00000185615 PMC2670002__F7 Pathway in colorectal cancer (CRC) progression from normal colon to late-stage cancer ENSG00000284816 ENSG00000196411 ENSG00000142627 ENSG00000154928 ENSG00000133216 PMC11012558__F6 RTK pathways ENSG00000134853 ENSG00000168610 ENSG00000146648 ENSG00000140443 PMC3798952__F1 EpCAM and WNT signalling pathways ENSG00000119888 ENSG00000134982 ENSG00000138798 ENSG00000168036 PMC11012558__F3 Calcium and Neural Stem Cell Proliferation ENSG00000133107 ENSG00000144935 ENSG00000167323 ENSG00000069018 ENSG00000293604 ENSG00000137672 ENSG00000077782 ENSG00000138741 PMC10970237__F5 Zein-Derived Peptides from Corn Promote the Proliferation of C2C12 Myoblasts via Crosstalk of mTORC1 and mTORC2 Signaling Pathways PMC11012558__F4 TRPVs and neural stem cell proliferation ENSG00000187688 ENSG00000138798 ENSG00000062485 PMC11003748__F2 Clastokines produced by osteoclasts and osteoclast precursors and interaction with their receptors on cells from the osteoblast lineage ENSG00000125266 ENSG00000154342 ENSG00000164932 ENSG00000169071 ENSG00000242252 ENSG00000162337 ENSG00000184347 ENSG00000170558 ENSG00000168036 ENSG00000168610 ENSG00000183018 ENSG00000143387 ENSG00000196411 ENSG00000163914 ENSG00000291837 ENSG00000128342 ENSG00000108821 ENSG00000185008 ENSG00000131196 PMC8620617__F4 Vitamin A Transporters in Visual Function: A Mini Review on Membrane Receptors for Dietary Vitamin A Uptake, Storage, and Transport to the Eye ENSG00000121207 ENSG00000138207 PMC7140477__F1 Major carbohydrate metabolic pathways ENSG00000166278 ENSG00000115419 ENSG00000026103 PMC11003748__F1 Matrix-derived coupling factors ENSG00000161921 ENSG00000198793 ENSG00000169884 ENSG00000168487 PMC3564224__F2 Therapeutic opportunities for targeting the ubiquitous cell surface receptor CD47 ENSG00000198053 ENSG00000291971 ENSG00000171791 PMC7959691__F4 PTP regulation of adhesion complexes and related pathways ENSG00000038382 ENSG00000070778 ENSG00000163629 ENSG00000291971 ENSG00000150457 ENSG00000131023 PMC5597736__F1 Interactions between DNA tumour viruses and the DNA damage response ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000163961 ENSG00000168610 ENSG00000112130 PMC9628250__F2 The Wnt signalling pathway in the energy metabolism of bone remodelling ENSG00000135218 ENSG00000115419 PMC9628250__F3 The Wnt signalling pathway in the energy metabolism of bone remodelling ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000168036 PMC3389016__F3 Anti-Obesity Sodium Tungstate Treatment Triggers Axonal and Glial Plasticity in Hypothalamic Feeding Centers ENSG00000223367 ENSG00000005882 ENSG00000288174 ENSG00000169032 ENSG00000168610 ENSG00000063177 ENSG00000171435 ENSG00000198576 ENSG00000185591 ENSG00000087250 ENSG00000110435 ENSG00000112306 ENSG00000091140 ENSG00000116120 ENSG00000173334 PMC9265870__F1 Breast Cancer Stem Cells: Signaling Pathways, Cellular Interactions, and Therapeutic Implications ENSG00000104856 ENSG00000106571 ENSG00000283780 ENSG00000134982 ENSG00000173039 ENSG00000168036 ENSG00000133961 ENSG00000184916 ENSG00000128602 ENSG00000213626 PMC9265870__F2 Breast Cancer Stem Cells: Signaling Pathways, Cellular Interactions, and Therapeutic Implications ENSG00000019991 ENSG00000108691 ENSG00000104432 ENSG00000057663 PMC5516940__F5 Downregulation of several proteins in the oxidative phosphorylation pathway identified in the global proteomic data for LNCaP-95 androgen resistant prostate cancer cells ENSG00000267855 ENSG00000143252 ENSG00000073578 ENSG00000138495 ENSG00000117118 ENSG00000292058 PMC9628250__F1 The Wnt signalling pathway in the energy metabolism of bone remodelling ENSG00000178860 ENSG00000188064 ENSG00000169884 PMC10037657__F1 Long Noncoding RNA H19: A Novel Oncogene in Liver Cancer ENSG00000198793 ENSG00000168040 PMC10838672__F1 VEGF protein family and receptor signaling pathway ENSG00000112715 ENSG00000150630 PMC12181099__F1 Interactive effects of MSC and AML cells on each other ENSG00000178860 ENSG00000107562 ENSG00000163739 ENSG00000163599 ENSG00000026508 ENSG00000108511 ENSG00000118971 ENSG00000165819 PMC10037657__F2 Long Noncoding RNA H19: A Novel Oncogene in Liver Cancer ENSG00000106683 ENSG00000070831 ENSG00000122691 ENSG00000149269 PMC10838672__F2 RTKs and its related downstream signaling pathways and their targeted therapies for hepatocellular carcinoma ENSG00000019991 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC10037657__F3 Long Noncoding RNA H19: A Novel Oncogene in Liver Cancer ENSG00000198793 PMC10838672__F3 PI3K/AKT/mTOR signaling pathway and targeted inhibitors ENSG00000002330 ENSG00000150907 ENSG00000146648 ENSG00000135250 PMC4385526__F2 Innate immune evasion of hepatitis C virus infection ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000185436 ENSG00000291876 ENSG00000164342 ENSG00000142166 PMC10838672__F4 Wnt on and Wnt off state of Wnt/B‐catenin signaling pathway and therapeutic strategies based on them ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC10838672__F5 JAK/STAT signaling and targeted inhibitors ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000173757 ENSG00000105639 ENSG00000168610 PMC10838672__F6 Smo‐driven canonical Hh signaling pathway and targeted inhibitors ENSG00000106571 ENSG00000166813 ENSG00000128602 PMC8079635__F1 Maintenance of Barrier Tissue Integrity by Unconventional Lymphocytes ENSG00000140564 ENSG00000099985 ENSG00000137033 ENSG00000109321 ENSG00000128342 ENSG00000100985 PMC9276080__F1 MicroRNAs and their signaling pathway in mycosis fungoides ENSG00000138378 ENSG00000103522 ENSG00000105639 ENSG00000168610 PMC9276080__F2 MicroRNAs and their signaling pathway in mycosis fungoides ENSG00000141867 ENSG00000168283 ENSG00000160856 ENSG00000168610 PMC8377203__F2 Unpicking the Roles of DNA Damage Protein Kinases in Trypanosomatids ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000310560 PMC8253276__F6 Upregulation of Nogo‐B by hypoxia inducible factor‐1 and activator protein‐1 in hepatocellular carcinoma ENSG00000070831 ENSG00000291971 PMC9626809__F1 Sulfur compounds in chronic obstructive pulmonary disease PMC7720622__F2 Estrogen signaling pathway with altered proteins in pterygium tear proteome in highlight ENSG00000082175 ENSG00000163235 ENSG00000113070 ENSG00000160182 ENSG00000171791 ENSG00000147654 ENSG00000146648 PMC8819303__F2 Aberrant RNA splicing and therapeutic opportunities in cancers ENSG00000100410 ENSG00000115524 ENSG00000063244 PMC10159521__F9 miR-613 suppresses renal cell carcinoma proliferation, invasion and migration by regulating the AXL/AKT pathway ENSG00000167601 PMC11992794__F5 Analyze the DEGs within metabolic pathways ENSG00000109814 ENSG00000156958 PMC6953055__F1 HBx-dysregulated miRNA in the P13K/MAPK liver cancer pathway ENSG00000019991 ENSG00000198793 PMC5668305__F7 The pain related mechanisms of Notch1 and TLR4 signaling pathway ENSG00000148400 ENSG00000136869 ENSG00000114315 PMC6953055__F2 Dysregulated miRNA in the WNT/Beta-catenin liver cancer pathway ENSG00000134982 ENSG00000168036 ENSG00000104447 PMC6953055__F3 Dysregulated miRNA in the TP53 liver cancer pathway ENSG00000132906 ENSG00000135446 ENSG00000105810 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC7493703__F1 Gene Polymorphisms in the CCL5/CCR5 Pathway as a Genetic Biomarker for Outcome and Hand–Foot Skin Reaction in Metastatic Colorectal Cancer Patients Treated With Regorafenib ENSG00000112715 PMC6953055__F4 Dysregulated miRNAs in the JAK/STAT liver cancer pathway ENSG00000198793 ENSG00000136997 PMC11932658__F1 n-6 and n-3 HUFA biosynthetic pathway ENSG00000134824 ENSG00000149485 ENSG00000197977 ENSG00000124920 PMC7729760__F1 Autophagy—A Hidden but Important Actor on Oral Cancer Scene ENSG00000177169 ENSG00000123395 ENSG00000198793 PMC3124877__F1 Pathway of alcoholic injury resulting in the direct production of oxidative stress and the LPS-TLR pathway that culminates in production of cytokines and other inflammatory processes that result in hepatitis of the liver ENSG00000130649 ENSG00000172936 ENSG00000136869 PMC9130956__F1 Atypical Cadherin FAT1 Limits Mitochondrial Respiration and Proliferation of Vascular Smooth Muscle Cells ENSG00000083857 ENSG00000122882 ENSG00000138798 PMC4238866__F3 Glucose activation of the cAMP-PKA pathway ENSG00000196511 ENSG00000116741 ENSG00000174840 PMC8718071__F8 Bile acid metabolism dysregulation associates with cancer cachexia: roles of liver and gut microbiome ENSG00000160867 ENSG00000276559 ENSG00000167434 ENSG00000135929 PMC7024330__F1 AR mediated gene transcription in different subtypes of breast cancer ENSG00000168036 ENSG00000129514 PMC3579397__F1 Sulfide production ENSG00000139531 PMC4238866__F1 The Snf1 protein kinase as a central player in the main glucose repression pathway ENSG00000196511 ENSG00000124253 PMC7024330__F2 AR signaling pathway and targeted therapeutic strategies against AR ENSG00000291971 ENSG00000203857 PMC11050151__F2 Representative scheme of the 15 genes shared by the selected pathways using pathway enrichment analysis ENSG00000081237 ENSG00000105647 ENSG00000073756 PMC7885480__F1 Developmental signaling that govern CSCs and therapy resistance ENSG00000186575 ENSG00000106571 ENSG00000134982 ENSG00000197905 ENSG00000168036 ENSG00000007866 ENSG00000164690 ENSG00000150457 ENSG00000128602 ENSG00000131023 ENSG00000196712 ENSG00000074219 PMC11050151__F3 Gene association networks that result from entering the list of eight genes—PIK3CG, PTGS2, FOS, PTPRC, VAV1, ITPR3, NFATC2, and PIK3R2—as input into the GeneMANIA software ENSG00000157404 ENSG00000065675 ENSG00000081237 ENSG00000130522 ENSG00000198851 ENSG00000163453 ENSG00000105647 ENSG00000187764 ENSG00000132510 ENSG00000049768 ENSG00000121879 ENSG00000124212 ENSG00000073756 ENSG00000141968 ENSG00000128272 ENSG00000110395 ENSG00000177606 ENSG00000095303 ENSG00000076641 ENSG00000070985 ENSG00000171608 ENSG00000146648 ENSG00000135605 PMC3469610__F6 Schematic diagram of proposed molecular mechanism of p27 downregulation in Fen-induced cell growth in fibroids ENSG00000123374 ENSG00000140443 PMC5392045__F1 Schematic of the stimulator of interferon genes (STING)–dependent innate immune response pathway ENSG00000183735 ENSG00000164430 PMC8002044__F4 Potential network of signaling pathways contributing to the chicken lipid metabolism ENSG00000135218 ENSG00000138135 ENSG00000116133 ENSG00000187288 ENSG00000099194 ENSG00000052802 PMC5133582__F7 Metabolic pathways in hepatocellular carcinoma ENSG00000112977 ENSG00000155926 ENSG00000006747 ENSG00000102977 PMC8002044__F2 Adipogenesis and fat deposition and their regulation at the transcriptional and post-transcriptional level in the chicken adipocyte ENSG00000042832 ENSG00000116133 ENSG00000127528 ENSG00000179348 PMC7500922__F4 Revisiting the PD-1 pathway ENSG00000168610 ENSG00000142166 PMC12042674__F2 Signaling pathways regulating melanin synthesis ENSG00000107165 PMC8873532__F1 Mitochondrial Nucleic Acid Sensing Pathways in Health and Patho-Physiology ENSG00000128272 ENSG00000144895 ENSG00000136758 PMC7654982__F3 Therapeutic Options to Block the Activation of Hedgehog Signaling Pathway ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC7920173__F1 Autoimmunity in Acute Poststreptococcal GN: A Neglected Aspect of the Disease ENSG00000039537 ENSG00000113600 ENSG00000166278 PMC7654982__F1 Hedgehog Pathway in Female Cancers ENSG00000128602 PMC7654982__F2 Abnormal Hedgehog Signaling Pathway Leads to Female Cancers ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC5006394__F2 Metabolism on Foxp3 expression and the generation of Treg cells ENSG00000150907 ENSG00000198793 ENSG00000049768 ENSG00000096717 PMC6307204__F5 NFKB signalling pathway is involved in endogenous DcR3 expression in HUVECs stimulated by LPS, LTA and zymosan ENSG00000226275 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC8843787__F1 Prostaglandin regulation of type 2 inflammation: From basic biology to therapeutic interventions ENSG00000121068 PMC4673016__F1 Transcriptional and chromatin regulation during fasting – The genomic era ENSG00000112561 ENSG00000163884 PMC8009749__F1 Roles of Adipocyte Extracellular Vesicle–Derived miRNAs in Obesity-Mediated Insulin Resistance ENSG00000100422 ENSG00000169047 ENSG00000189043 ENSG00000136826 PMC8063120__F4 Long non-coding RNA (lncRNAs) and microRNAs (miRNAs) involved in osteogenic pathways in Bone Marrow Mesenchymal Stem Cells (BMSCs) ENSG00000170365 ENSG00000137834 ENSG00000134982 ENSG00000198742 ENSG00000168036 PMC7461616__F1 Targeting lipid metabolism of myeloid cells in cancer immunotherapy ENSG00000239732 ENSG00000163599 ENSG00000121807 ENSG00000026103 PMC8055485__F1 Signaling pathways behind the role of CRP in cancer-induced muscle wasting ENSG00000169047 ENSG00000198793 ENSG00000173039 ENSG00000162924 ENSG00000168610 ENSG00000132693 ENSG00000140443 PMC7561410__F2 Signaling pathways in the epididymitis induced by UEPC ENSG00000187554 ENSG00000172936 ENSG00000136869 PMC3692518__F4 miRNA Signature of Mouse Helper T Cell Hyper-Proliferation ENSG00000136158 ENSG00000164056 ENSG00000213658 ENSG00000149269 ENSG00000040199 PMC8960951__F1 Role of Chronic Physical Exercise as a Treatment in the Development of Vitiligo ENSG00000169245 ENSG00000186810 ENSG00000134982 ENSG00000125538 ENSG00000138755 ENSG00000049768 PMC4016161__F1 The succinate dehydrogenase complex (SDH), as a member of the tricarboxylic acid cycle (TCA), catalyzes the oxidation of succinate to fumarate ENSG00000143252 ENSG00000182511 ENSG00000073578 ENSG00000117118 PMC12114673__F9 Schematic diagram illustrating the mechanism of CCNB1 in melanoma cells resisting NK cell-mediated cytotoxicity ENSG00000111537 ENSG00000134057 ENSG00000231179 ENSG00000204520 ENSG00000168610 PMC3482366__F1 Summary of folate metabolic pathway ENSG00000088305 ENSG00000124275 ENSG00000116984 PMC7601352__F2 Screening of key genes related to the prognosis of mouse sepsis ENSG00000123240 ENSG00000291603 ENSG00000105329 ENSG00000044115 ENSG00000141068 ENSG00000124126 ENSG00000149781 ENSG00000179588 ENSG00000182957 ENSG00000064666 ENSG00000102145 ENSG00000140682 ENSG00000066336 ENSG00000090686 ENSG00000071051 ENSG00000130402 ENSG00000113263 ENSG00000188677 ENSG00000140464 ENSG00000104365 ENSG00000264522 ENSG00000143549 ENSG00000005961 ENSG00000170027 ENSG00000081237 ENSG00000027697 ENSG00000170035 ENSG00000291420 ENSG00000063245 ENSG00000115415 ENSG00000177606 ENSG00000123143 ENSG00000115232 ENSG00000198625 PMC8350018__AF1 Bisphenol A-induced DNA damages promote to lymphoma progression in human lymphoblastoid cells through aberrant CTNNB1 signaling pathway ENSG00000122691 ENSG00000168036 ENSG00000124762 ENSG00000138385 PMC12042419__F4 Schematic illustration of NOTCH3 signaling pathway involvement in the pathogenesis of CADASIL ENSG00000168214 ENSG00000283780 ENSG00000074181 ENSG00000163914 ENSG00000137845 PMC3427155__F2 Analysis of Differential miRNA Expression in the Duodenum of Escherichia coli F18-Sensitive and -Resistant Weaned Piglets ENSG00000121989 ENSG00000107562 ENSG00000173482 ENSG00000187764 ENSG00000121879 ENSG00000109819 ENSG00000103479 ENSG00000245848 ENSG00000109861 ENSG00000081377 ENSG00000269858 ENSG00000136040 ENSG00000119541 ENSG00000197081 ENSG00000291420 ENSG00000120063 ENSG00000101972 ENSG00000110395 ENSG00000134853 ENSG00000140285 ENSG00000143322 ENSG00000136160 ENSG00000134243 ENSG00000168646 ENSG00000115232 ENSG00000146648 ENSG00000113448 ENSG00000171408 PMC11640101__F4 Involvement of the ARF6-AMAP1 pathway and Arid5a in cancer progression and immune evasion ENSG00000185236 ENSG00000196843 ENSG00000108691 ENSG00000115109 ENSG00000165527 ENSG00000159399 PMC9485629__F1 Molecular mechanisms of histone deacetylases and inhibitors in renal fibrosis progression ENSG00000138798 ENSG00000146648 PMC3351290__F10 TRPC1 channel is a major regulator of EGFR signaling ENSG00000112576 ENSG00000144935 ENSG00000167323 ENSG00000138798 ENSG00000146648 PMC12038022__F2 Molecular mechanisms of ferroptosis and disulfidptosis ENSG00000168003 ENSG00000104812 ENSG00000151012 ENSG00000131495 ENSG00000167468 ENSG00000163902 ENSG00000072274 ENSG00000111684 ENSG00000061676 ENSG00000115107 ENSG00000127948 PMC3748092__F8 Cell Surface Glycan Alterations in Epithelial Mesenchymal Transition Process of Huh7 Hepatocellular Carcinoma Cell ENSG00000069482 ENSG00000183778 ENSG00000179163 PMC11640101__F1 Metabolic reprogramming in cancer ENSG00000131473 ENSG00000113161 ENSG00000169710 ENSG00000159399 PMC10473115__F1 Untangling the Role of TREM2 in Conjugation with Microglia in Neuronal Dysfunction: A Hypothesis on a Novel Pathway in the Pathophysiology of Alzheimer’s Disease ENSG00000112977 PMC10473115__F2 Untangling the Role of TREM2 in Conjugation with Microglia in Neuronal Dysfunction: A Hypothesis on a Novel Pathway in the Pathophysiology of Alzheimer’s Disease ENSG00000112977 ENSG00000124181 PMC10473115__F3 Untangling the Role of TREM2 in Conjugation with Microglia in Neuronal Dysfunction: A Hypothesis on a Novel Pathway in the Pathophysiology of Alzheimer’s Disease ENSG00000197943 PMC6468748__F1 Moonlighting functions of the endothelial protein C receptor (EPCR) ENSG00000134982 ENSG00000173599 ENSG00000122194 PMC9047859__F2 Functions of Stress-Induced Lipid Droplets in the Nervous System ENSG00000189058 ENSG00000169710 PMC3489622__F2 Signaling networks induced in the spleen at 1 day post infection in wild-type mice (A) and STAT1 KO mice (B) ENSG00000213928 ENSG00000117228 ENSG00000185201 ENSG00000067606 ENSG00000157601 ENSG00000160710 ENSG00000151929 ENSG00000112715 ENSG00000125347 ENSG00000276561 ENSG00000113494 PMC7705468__F1 Mechanisms involved in the tenocytes during the process of diabetic tendinopathy ENSG00000125398 ENSG00000150907 ENSG00000260428 PMC7705468__F2 Mechanisms involved in the tendon stem/progenitor cells during the process of diabetic tendinopathy ENSG00000161905 ENSG00000125398 ENSG00000198793 ENSG00000260428 ENSG00000000005 ENSG00000171051 PMC10473115__F4 Untangling the Role of TREM2 in Conjugation with Microglia in Neuronal Dysfunction: A Hypothesis on a Novel Pathway in the Pathophysiology of Alzheimer’s Disease ENSG00000112977 ENSG00000197943 PMC3382911__F1 Colon cancer cells produce immunoregulatory glucocorticoids ENSG00000138798 ENSG00000145321 PMC4178135__F3 Standardized pathway diagram calculated with a structural equation model of antepartal hormones in pluriparous dairy cows PMC3202514__F1 Maturational changes in fatty acid and carbohydrate metabolism gene expression PMC5086085__F5 Ecdysone receptor B1 (EcR‐B1) signaling to trigger pruning in MB G and da neurons ENSG00000168875 ENSG00000140287 ENSG00000165280 ENSG00000198125 PMC6966863__F7 Mechanism for ABC transporters regulated by the level of PI3K 110A or 110B subunit ENSG00000002330 ENSG00000005882 ENSG00000198793 PMC8443474__F1 Aryl hydrocarbon receptor in liver inflammation ENSG00000110711 ENSG00000140505 ENSG00000106546 PMC8066875__F8 NFKB pathway and NLRP3 inflammasome activation and role of some microRNAs ENSG00000278718 ENSG00000162711 ENSG00000125538 ENSG00000169047 ENSG00000198793 ENSG00000145020 ENSG00000175104 ENSG00000184216 PMC6722943__F9 Differentially expressed genes associated with the p53 signaling pathway ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000002330 ENSG00000136997 ENSG00000123374 ENSG00000112378 PMC7896869__F7 Involvement of SAB in enhancing proliferation and attenuating oxidative stress and apoptosis through activation of the JAK2/STAT3 signaling pathway ENSG00000168610 PMC6659998__F3 FA/TAG metabolism in hepatocytes ENSG00000166819 ENSG00000131473 ENSG00000151726 ENSG00000117054 ENSG00000187048 ENSG00000135218 ENSG00000178537 ENSG00000187288 ENSG00000169710 ENSG00000285482 ENSG00000076555 ENSG00000062282 PMC11603636__F7 Schematic mechanisms concerning the IRE1Alpha-XBP1 axis in LPS-induced acute lung injury ENSG00000162711 ENSG00000265972 ENSG00000100219 PMC8165189__F1 Hippo Signaling Pathway in Pancreas Development ENSG00000091704 ENSG00000125398 ENSG00000139515 ENSG00000168267 ENSG00000131023 PMC7981372__F5 Exploring the role of Azadirachta indica (neem) and its active compounds in the regulation of biological pathways: an update on molecular approach ENSG00000132646 ENSG00000171791 ENSG00000100985 PMC4219592__F1 Interactions between alcohol-induced mechanisms leading to hepatic carcinogenesis ENSG00000130649 ENSG00000136869 ENSG00000166278 PMC11759193__F7 Mechanistic overview scheme of the effects of aircraft noise on endothelial function ENSG00000129226 ENSG00000079999 PMC5520851__F1 mTORC1 controls cell growth and is regulated by the lncRNA-encoded polypeptide SPAR ENSG00000177169 ENSG00000169047 ENSG00000171540 PMC6711114__F1 The main enzyme pathways involved in mitochondrial pyrimidine dNTPs metabolism ENSG00000158825 ENSG00000167900 ENSG00000129187 PMC6596841__F1 Gpr17 signaling pathway following lysolecithin insult ENSG00000132530 ENSG00000205927 PMC4831565__F4 GAPDH nitrosylation pathway mediates cocaine effects ENSG00000101945 ENSG00000196470 PMC9130470__F3 NTRK Fusions in a Sarcomas Series: Pathology, Molecular and Clinical Aspects PMC5177915__F8 Citrus flavonoid naringenin confers protection in a murine endotoxaemia model through AMPK-ATF3-dependent negative regulation of the TLR4 signalling pathway ENSG00000136869 ENSG00000162772 PMC8165189__F2 Hippo Signaling Pathway in Pancreas Development ENSG00000147862 ENSG00000148926 ENSG00000150457 ENSG00000131023 PMC3984774__F4 RB/E2F pathway ENSG00000145604 ENSG00000135446 ENSG00000136997 PMC8123608__F3 Autoinflammatory Features in Gouty Arthritis ENSG00000162594 ENSG00000162711 ENSG00000149972 ENSG00000164219 ENSG00000170458 ENSG00000186480 ENSG00000136869 ENSG00000136859 PMC7554785__F3 Reduced TCF1 expression promoting a differentiation bias of activated aged T cells toward terminal effector cells ENSG00000134460 ENSG00000138795 ENSG00000198793 ENSG00000020633 PMC3889649__F5 GLI1 target genes converge on a regulatory pathway that suggests roles in cell proliferation, survival and genomic stability ENSG00000100811 ENSG00000181163 ENSG00000010810 ENSG00000136997 ENSG00000147133 ENSG00000170430 ENSG00000168036 ENSG00000129514 ENSG00000205250 ENSG00000143333 ENSG00000161542 PMC6306051__F7 Knockdown of nucleophosmin 1 suppresses proliferation of triple-negative breast cancer cells through activating CDH1/Skp2/p27kip1 pathway ENSG00000145604 ENSG00000181163 PMC8159873__F3 Cellular pathways involved in trained immunity ENSG00000162711 ENSG00000135218 ENSG00000134982 ENSG00000198793 ENSG00000175104 ENSG00000140443 PMC125566__F1A Negative regulation of the Wnt–Beta-catenin pathway by the transcriptional repressor HBP1 ENSG00000134982 ENSG00000168036 PMC3413017__F1 Apoptosis and necrosis ENSG00000149311 ENSG00000168040 PMC5645527__F1 WNT signaling pathway activation ENSG00000281324 ENSG00000125398 ENSG00000162337 ENSG00000134982 ENSG00000026508 ENSG00000168036 PMC8851273__F9 Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling ENSG00000168610 PMC5948853__F8 A schematic of the model of crosstalk between STAT1 and TGFB signaling pathways PMC9093150__F10 Working hypothesis of the role of the prostanoid pathway in angiogenesis inhibitor-induced hypertension and renal injury ENSG00000138336 PMC3360095__F1 P2X4R-p38 MAPK is a core signaling pathway through which spinal microglia and peripheral macrophages contribute to neuropathic pain and inflammatory pain ENSG00000137077 PMC6147237__F1 A Combined In Vitro/In Silico Approach to Identifying Off-Target Receptor Toxicity ENSG00000010671 PMC7047255__F7 Pathway interaction schematic constructed to demonstrate overlap of gene expression data with critical osteogenic pathways ENSG00000178860 ENSG00000170365 ENSG00000106571 ENSG00000242252 ENSG00000118785 ENSG00000120149 ENSG00000291837 ENSG00000168036 ENSG00000128602 ENSG00000204217 PMC8847686__F10 Network Pharmacology-Based and Experimental Identification of the Effects of Paeoniflorin on Major Depressive Disorder ENSG00000102871 ENSG00000127191 PMC6351482__F4 Mutation enrichment of Nectin adhesion pathway ENSG00000006607 ENSG00000259207 ENSG00000070831 ENSG00000044115 ENSG00000291971 ENSG00000140575 ENSG00000173482 ENSG00000168036 ENSG00000186111 ENSG00000121879 ENSG00000107263 ENSG00000137076 ENSG00000160293 PMC6095456__F1 Regulation of innate immune cell function by mTOR ENSG00000140992 ENSG00000117020 ENSG00000167461 ENSG00000150907 ENSG00000198793 ENSG00000118515 ENSG00000164327 ENSG00000159399 PMC10892755__F1 Cholesterol and isoprenoid synthesis pathway illustrating how statins inhibit the enzyme 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase ENSG00000070831 PMC4568555__F1 Key transduction molecules of ErbB signaling pathway known to regulate cardiomyocyte viability and function ENSG00000002330 ENSG00000198793 ENSG00000026103 PMC8182305__F2 Aquaporins in insulin resistance and diabetes: More than channels! ENSG00000178301 ENSG00000103569 ENSG00000165269 PMC5715262__F3 Molecular pathways around CIC in cancer ENSG00000224470 ENSG00000130638 ENSG00000079432 ENSG00000118971 PMC4698395__F5 Mechanisms of stretch-induced reactive oxygen species (ROS) production and Ca2+ influx in dystrophic muscle ENSG00000182533 ENSG00000291971 ENSG00000196218 PMC7896225__F1 Proposed neuroprotective role of Withaferin A (WA) in the modulation of pathways implicated in neurological abnormalities and dysfunctions.Parkinson’s disease (PD): WA is a known inhibitor of the Cdc37/Hsp90 complex ENSG00000105401 PMC5392045__F2 Interplay between autophagy, apoptosis, and the stimulator of interferon genes (STING) pathway ENSG00000183735 ENSG00000164430 PMC7144958__F1 XPF–ERCC1: Linchpin of DNA crosslink repair ENSG00000012061 ENSG00000188827 ENSG00000276787 PMC4417466__F5 RPPA analysis in HeyA8-MDR treated with ZA ENSG00000087245 ENSG00000142192 ENSG00000002330 ENSG00000291971 ENSG00000173039 ENSG00000168036 ENSG00000132478 ENSG00000168610 ENSG00000187840 ENSG00000089159 ENSG00000115290 ENSG00000136997 ENSG00000291837 ENSG00000051180 ENSG00000095002 ENSG00000139687 ENSG00000146648 PMC3376380__F1 mTOR signaling and its regulation by DGKs ENSG00000198793 ENSG00000164327 PMC3841787__F5 Proposed signaling pathway model for VEGF-A signaling in hypoxia-stressed BM-EPCs compiled from the proteomic and gene expression analysis is highlighted here ENSG00000163914 ENSG00000036828 ENSG00000112715 ENSG00000137766 ENSG00000007171 PMC4446705__F1 The IL-4 and IL-13 receptor signaling pathways ENSG00000123496 ENSG00000105397 ENSG00000169047 ENSG00000033800 ENSG00000131724 ENSG00000118520 ENSG00000105639 ENSG00000168610 PMC4687899__F2 Pancreatic Cancer Metabolism - Breaking it down to build it back up ENSG00000125166 ENSG00000065833 ENSG00000197713 ENSG00000198380 ENSG00000153574 ENSG00000115419 ENSG00000159399 PMC6322405__F1 Hippo signaling network and its biological functions ENSG00000147162 ENSG00000291971 ENSG00000163681 PMC5587470__F7 Diagram of muscle‐growth signaling pathway and differentially expressed genes, thus summarizing the effect of thermal gradient on muscle growth ENSG00000198793 ENSG00000140443 PMC1180390__F5 Signaling pathways implicating p120-RasGAP ENSG00000169291 ENSG00000115904 PMC9200993__F1 Treg Cell Metabolism and Function in Non-Lymphoid Tissues ENSG00000138378 ENSG00000137033 ENSG00000156127 ENSG00000137265 ENSG00000168036 ENSG00000107485 PMC2883511__F1 Signaling pathways and targets for LAM ENSG00000198793 ENSG00000163914 PMC6816394__F5 Role of tPA in the proliferative signaling and Wnt/Beta-catenin signaling ENSG00000168036 PMC7015009__F1 Hic-5-mediated signaling pathways for tumor progression ENSG00000291971 ENSG00000100985 PMC6637639__F1 Interaction network of proteins underexpressed in in vitro matured cumulus complexes (interaction confidence: high (> 0.7), database matches n = 82) ENSG00000186049 ENSG00000152661 ENSG00000196975 ENSG00000142798 ENSG00000122218 ENSG00000163064 ENSG00000120885 ENSG00000122194 ENSG00000163815 ENSG00000236625 ENSG00000106927 ENSG00000163631 ENSG00000180210 ENSG00000196136 ENSG00000198380 ENSG00000121410 ENSG00000189171 ENSG00000158874 ENSG00000171560 ENSG00000254709 ENSG00000261701 ENSG00000113889 ENSG00000162551 ENSG00000151655 ENSG00000074319 ENSG00000000971 ENSG00000257335 ENSG00000163661 ENSG00000113905 ENSG00000100280 ENSG00000001561 ENSG00000117601 ENSG00000175899 ENSG00000167996 ENSG00000145321 ENSG00000123838 ENSG00000276838 ENSG00000262243 PMC6443908__F7 APR signaling pathway is associated with ozone exposure and bacterial infection ENSG00000071564 ENSG00000145192 ENSG00000105697 ENSG00000196628 ENSG00000106927 PMC7767264__F4 Representation of genes/pathways/transcription factors identified from host–pathogen interaction during aflatoxin production ENSG00000105722 PMC6637639__F2 Interaction network of proteins overexpressed in in vitro matured cumulus complexes (interaction confidence: high (> 0.7), database matches n = 116) ENSG00000182481 ENSG00000133265 ENSG00000065911 ENSG00000185070 ENSG00000124614 ENSG00000175220 ENSG00000197746 ENSG00000169710 ENSG00000132182 ENSG00000118971 ENSG00000167508 ENSG00000116161 ENSG00000164237 ENSG00000184164 ENSG00000071082 ENSG00000076043 ENSG00000097021 ENSG00000196935 ENSG00000145741 ENSG00000103316 ENSG00000112655 ENSG00000123342 ENSG00000151364 ENSG00000054116 ENSG00000102316 ENSG00000184575 ENSG00000123983 ENSG00000141556 ENSG00000156049 ENSG00000091972 ENSG00000130638 ENSG00000179950 ENSG00000106483 ENSG00000099194 ENSG00000145391 ENSG00000242372 ENSG00000107949 ENSG00000167986 ENSG00000116649 ENSG00000146648 ENSG00000116761 ENSG00000111642 ENSG00000152556 ENSG00000073737 PMC8664701__F2 Nutritional therapy can reduce the burden of depression management in low income countries: A review PMC7726231__F3 Raptor silencing down-regulated components of mTORC1 (RPTOR, RPS15 A, RPS28) but not mTORC2 signaling in PHT cells ENSG00000177169 ENSG00000163435 ENSG00000171105 ENSG00000198793 ENSG00000163914 ENSG00000173599 PMC9200993__F2 Treg Cell Metabolism and Function in Non-Lymphoid Tissues ENSG00000236637 ENSG00000135218 ENSG00000167468 ENSG00000198793 ENSG00000113161 ENSG00000049768 ENSG00000096717 PMC7817101__F8 Annexin-A1 SUMOylation regulates microglial polarization after cerebral ischemia by modulating IKKA stability via selective autophagy ENSG00000188554 ENSG00000188612 PMC10487928__F5 Delta interactome of the top 20 most connected differentially expressed genes (DEGs), defense response to virus genes, angiogenesis genes, adaptive and innate immune genes, and SARS-CoV-2 proteins ENSG00000116663 ENSG00000106785 ENSG00000187608 ENSG00000089127 ENSG00000164251 ENSG00000101782 ENSG00000157601 ENSG00000179750 ENSG00000121236 ENSG00000166851 ENSG00000178685 ENSG00000093009 ENSG00000078081 ENSG00000051180 ENSG00000258659 ENSG00000140464 ENSG00000117228 ENSG00000122966 ENSG00000275126 ENSG00000185745 ENSG00000073756 ENSG00000276561 ENSG00000133216 ENSG00000276410 ENSG00000196411 ENSG00000117226 ENSG00000112984 ENSG00000135114 ENSG00000123838 ENSG00000111331 PMC6135718__F6 Potential lymphangiogenesis therapies: learning from current anti-angiogenesis therapies - A review ENSG00000198793 ENSG00000146648 PMC4523862__F8 USP18 negatively regulates NFKB signaling by targeting TAK1 and NEMO for deubiquitination through distinct mechanisms ENSG00000184979 ENSG00000172936 ENSG00000157625 ENSG00000175104 PMC11121022__F1 Systemic sclerosis, recognized as a prototypical autoimmune disease, is intricately governed by a myriad of autoimmune mechanisms ENSG00000179344 ENSG00000105397 ENSG00000134982 ENSG00000168811 PMC4173667__F7 Schematic representation of a possible inflammatory pathway ENSG00000026508 ENSG00000172936 PMC6813799__F1 Key Steps of Reverse Cholesterol Transport ENSG00000130164 ENSG00000100979 ENSG00000073734 ENSG00000160179 PMC8980436__F3 Cancer Metabolism: The Role of Immune Cells Epigenetic Alteration in Tumorigenesis, Progression, and Metastasis of Glioma ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC8217759__F7 M2a Macrophage-Secreted CHI3L1 Promotes Extracellular Matrix Metabolic Imbalances via Activation of IL-13RA2/MAPK Pathway in Rat Intervertebral Disc Degeneration ENSG00000123496 ENSG00000133048 ENSG00000149968 ENSG00000100985 PMC11754067__F1 Structure and formation mechanism of KL-la, KD-la and Kce ENSG00000171720 ENSG00000283100 PMC8063606__F2 Pack a STRIPAK with hubs inside a hub ENSG00000150457 ENSG00000131023 PMC8326263__F3 Gastrointestinal and hepatic diseases during the COVID-19 pandemic: Manifestations, mechanism and management ENSG00000131142 ENSG00000110799 ENSG00000198793 ENSG00000112115 PMC5388549__F9 Proposed mechanism for the effect of FPS-ZM1 in COPD ENSG00000197956 ENSG00000189403 PMC8417791__F1 An Insight on Multicentric Signaling of Angiotensin II in Cardiovascular system: A Recent Update ENSG00000130234 PMC4107617__F3 Group I mGluR-signaling pathway in immune cells ENSG00000125538 ENSG00000177606 PMC6887802__F2 COPD and autophagy pathway ENSG00000177169 ENSG00000069482 ENSG00000126775 ENSG00000198793 ENSG00000144848 PMC5828319__F4 CD200R-induced signaling pathway ENSG00000115415 ENSG00000291971 PMC5828319__F2 Inhibition mechanism of IL-12 production through interaction of TIM-3 and Gal-9 ENSG00000115415 ENSG00000291971 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000168610 ENSG00000135605 PMC6829368__F9 Network of the glutathione metabolism pathway ENSG00000178814 ENSG00000167325 ENSG00000116649 PMC6144915__F2 Pathway-pathway crosstalk via GADD45B ENSG00000135446 ENSG00000132646 ENSG00000099860 ENSG00000105810 PMC9550190__F1 Conducive target range of breast cancer: Hypoxic tumor microenvironment ENSG00000108691 ENSG00000107562 ENSG00000198053 ENSG00000198793 ENSG00000118520 ENSG00000168610 ENSG00000146648 PMC9550190__F2 Conducive target range of breast cancer: Hypoxic tumor microenvironment ENSG00000107562 ENSG00000049768 ENSG00000168610 ENSG00000146648 ENSG00000121966 PMC7773221__F2 Common regulatory proteins of the complement and coagulation systems ENSG00000009724 ENSG00000291559 ENSG00000134982 ENSG00000288512 ENSG00000182326 ENSG00000236625 PMC9266536__F1 Fenretinide in Cancer and Neurological Disease: A Two-Face Janus Molecule ENSG00000005882 PMC7024175__F1 CAMKK2 signaling pathway ENSG00000152495 ENSG00000110931 PMC6639181__F9 Summary scheme represents the possible pathways of drug sensitive and drug resistance to cordycepin in MA‐10 mouse Leydig tumor cells ENSG00000128272 ENSG00000144895 ENSG00000135446 ENSG00000198793 ENSG00000100219 ENSG00000162772 PMC4848973__F5 Matrix Hyaluronan Promotes Specific MicroRNA Upregulation Leading to Drug Resistance and Tumor Progression ENSG00000128710 ENSG00000026508 ENSG00000171791 PMC8268881__F4 Intraductal Papillary Mucinous Carcinoma Versus Conventional Pancreatic Ductal Adenocarcinoma: A Comprehensive Review of Clinical-Pathological Features, Outcomes, and Molecular Insights ENSG00000165556 ENSG00000108375 ENSG00000087460 PMC3479319__F1 Wnt signaling cascadesWnt signals can be transduced either through the canonical pathway (colored in pink) or different non-canonical pathways ENSG00000134982 ENSG00000198793 ENSG00000163914 ENSG00000177606 ENSG00000168036 PMC6887802__F3 Lung cancer and autophagy pathway ENSG00000177169 ENSG00000198793 PMC4991494__F6 Quantification of mutant alleles in circulating tumor DNA can predict survival in lung cancer ENSG00000149311 ENSG00000005339 ENSG00000253729 PMC6887802__F4 Infectious lung disease and autophagy pathway ENSG00000177169 ENSG00000110497 ENSG00000111537 ENSG00000126775 ENSG00000198793 ENSG00000175104 PMC6887802__F6 Pulmonary arterial hypertension and autophagy pathway ENSG00000177169 ENSG00000198793 ENSG00000057663 PMC6963221__F1 Sensing of Dengue virus by the innate immune responses and multiple evasion strategies to hinder the production of type I interferons (IFN).The upper panel shows the sensing of viral infection by RIG-I and cGAS ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000263528 ENSG00000114127 ENSG00000121060 ENSG00000142166 PMC7708667__F1 Biglycan determines pro- and anti-inflammatory signaling response by switching between TLR2/TLR4/CD14 and TLR4/CD44 ENSG00000162711 ENSG00000150782 ENSG00000170458 ENSG00000026508 ENSG00000172936 ENSG00000136869 PMC6887802__F7 Acute lung injury and autophagy pathway ENSG00000177169 ENSG00000198793 PMC8082393__F8 Comprehensive RNA-Seq Analysis of Potential Therapeutic Targets of Gan–Dou–Fu–Mu Decoction for Treatment of Wilson Disease Using a Toxic Milk Mouse Model ENSG00000157184 ENSG00000169291 ENSG00000150991 ENSG00000100979 PMC6498606__F7 Model of PAPP-A-driven PABC ENSG00000162733 ENSG00000166173 ENSG00000115461 PMC9359464__F4 Emerging advances in identifying signal transmission molecules involved in the interaction between Mycobacterium tuberculosis and the host ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC10418609__F8 Expression of the DBNDD1 signaling pathway in prostate cancer (MetaCore) ENSG00000002330 ENSG00000134982 ENSG00000169047 ENSG00000165879 ENSG00000077782 ENSG00000102468 PMC4779130__F2 Signals involved in early granuloma formation ENSG00000169248 ENSG00000186810 ENSG00000100985 PMC9359464__F3 Emerging advances in identifying signal transmission molecules involved in the interaction between Mycobacterium tuberculosis and the host ENSG00000116717 ENSG00000119383 PMC5603903__F8 Schematic diagram summarizing factors influencing the signaling efficacy of the TLR2/1-VDR pathway in response to TLR2/1 elicitation ENSG00000152266 ENSG00000105516 ENSG00000150455 PMC7605288__F1 Caudal-related homeobox transcription factor 2 plays different roles in embryo, intestinal epithelium and colorectal cancers ENSG00000149311 ENSG00000165556 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000123374 ENSG00000168646 PMC4605623__F10 The Fanconi Anemia C Protein Binds to and Regulates Stathmin-1 Phosphorylation ENSG00000152495 ENSG00000158169 PMC9678611__F4 Prediction of network pharmacology and molecular docking-based strategy to determine potential pharmacological mechanism of Liuwei Dihuang pill against tinnitus ENSG00000134086 ENSG00000183691 ENSG00000072274 ENSG00000136869 ENSG00000166278 ENSG00000088926 PMC7429716__F1 G2/M checkpoint signaling pathway ENSG00000175054 ENSG00000123374 PMC4301714__F1 Simplified model of the Rag4-KlRgt1 glucose signaling pathway controlling RAG1 gene expression ENSG00000166349 ENSG00000074800 ENSG00000047597 PMC3465335__F4 Temperature Dependent Proteomic Analysis of Thermotoga maritima ENSG00000100417 PMC4345858__F9 Acsl1‐dependent changes in metabolites in the biochemical pathway involving cysteine and glutathione metabolism ENSG00000128965 PMC12067746__F7 Graphical illustration of the working model ENSG00000049768 PMC5464940__F1 MOA of CHST15/CS-E and STNM01 in tissue remodeling in IBD ENSG00000108691 ENSG00000168036 PMC7818425__F6 Selected features and functions ENSG00000103811 ENSG00000134460 ENSG00000107249 ENSG00000116793 ENSG00000177688 ENSG00000168685 PMC538777__F7 Novel Jun-Dmp1 pathway ENSG00000135446 ENSG00000136997 ENSG00000152592 PMC5419568__F5 Blocking Smad2 signalling with loganin attenuates SW10 cell cycle arrest induced by TNFA ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000168040 PMC8997587__F11 Metabolic Reprogramming in HIV-Associated Neurocognitive Disorders ENSG00000011304 PMC6628899__F1 Ipilimumab in prostate cancer ENSG00000134982 ENSG00000163599 PMC10420159__F1 Immune checkpoints in a tumor microenvironment (TME) ENSG00000114455 ENSG00000089692 PMC3090458__F3 BAFF and APRIL signaling pathways in B cells ENSG00000239732 ENSG00000082512 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC6721552__F3 Simplified overview of the MAPK and PI3K pathway ENSG00000198793 ENSG00000196712 PMC3108097__F1 Iron Homeostasis and the Inflammatory Response ENSG00000010704 ENSG00000106327 ENSG00000128791 ENSG00000100219 ENSG00000130513 PMC6332843__F2 PD-1 signaling in B cells and T cells ENSG00000291603 ENSG00000135218 ENSG00000186716 ENSG00000197943 PMC7175146__F2 Structure of the neurovascular unit (NVU) with particular attention to the glucose metabolism impairment ENSG00000171885 PMC8958553__F1 AKI and CKD affect FGF23 via inflammatory, iron deficiency, anemia, and metabolic related pathways ENSG00000118972 ENSG00000148346 ENSG00000293604 ENSG00000150907 ENSG00000198793 ENSG00000198670 ENSG00000168610 PMC3995856__F4 Pathway analysis and molecular interactions of focus genes AKT, CTNNB1, GAB2, and SERPINE1 (hightlighted in pink) ENSG00000109452 ENSG00000033327 ENSG00000130158 ENSG00000163629 ENSG00000164078 ENSG00000168036 ENSG00000152137 ENSG00000288169 PMC7465203__F1 The Wnt pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11816803__F9 Figure illustrates simplified pathways involved in the development and progression of EC based on KEGG BRITE data (BRITE accession ID: K04503, pathway map ID: map05213) ENSG00000132906 ENSG00000002330 ENSG00000134982 ENSG00000168036 ENSG00000122008 PMC4292165__F1 Signaling pathway of cell surface TLRs ENSG00000134970 ENSG00000174125 ENSG00000115008 ENSG00000135218 ENSG00000150455 ENSG00000183735 ENSG00000170458 ENSG00000125538 ENSG00000160703 ENSG00000134070 ENSG00000157625 ENSG00000136869 ENSG00000172936 ENSG00000131323 PMC4292165__F2 Signaling pathway of endosomal TLRs ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC4322524__F1 Signalling pathways that control maintenance of BCSCsWnt binds its co-receptors: Frizzled (Fz) and LRP5/LRP6 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000164690 PMC6326667__F5 Environmental enrichment largely prevented age-SNCA-dependent disturbances and activated topologically relevant genes in the SNCA interactome with respect to both disturbance modes ENSG00000064490 ENSG00000042832 ENSG00000214113 ENSG00000095951 ENSG00000099860 ENSG00000124126 ENSG00000010278 ENSG00000079432 ENSG00000118971 ENSG00000158869 ENSG00000111348 ENSG00000164305 ENSG00000236625 ENSG00000160469 ENSG00000095585 ENSG00000173369 ENSG00000066117 ENSG00000157890 ENSG00000164405 ENSG00000292234 ENSG00000122756 ENSG00000092621 ENSG00000157227 ENSG00000132326 ENSG00000232119 ENSG00000107731 ENSG00000165646 ENSG00000283060 ENSG00000105662 ENSG00000089169 ENSG00000162975 ENSG00000137806 ENSG00000130764 ENSG00000111328 ENSG00000184983 ENSG00000064393 ENSG00000113140 ENSG00000131095 ENSG00000004779 ENSG00000104408 ENSG00000165264 ENSG00000149311 ENSG00000153208 ENSG00000173372 ENSG00000133112 ENSG00000163131 ENSG00000186010 ENSG00000164708 PMC5354927__F1 Dysregulation of long non-coding RNA in breast cancer: an overview of mechanism and clinical implication ENSG00000084093 ENSG00000137077 PMC5354927__F2 Dysregulation of long non-coding RNA in breast cancer: an overview of mechanism and clinical implication ENSG00000171720 PMC4292165__F3 RLR Signaling pathway ENSG00000183735 ENSG00000131323 ENSG00000083799 ENSG00000121060 ENSG00000101695 PMC9250200__F2 Follicle-stimulating hormone signaling in Sertoli cells: a licence to the early stages of spermatogenesis ENSG00000117480 ENSG00000170558 ENSG00000198793 ENSG00000103375 ENSG00000277641 ENSG00000070669 PMC9250200__F3 Follicle-stimulating hormone signaling in Sertoli cells: a licence to the early stages of spermatogenesis ENSG00000104899 ENSG00000198793 PMC9250200__F1 Follicle-stimulating hormone signaling in Sertoli cells: a licence to the early stages of spermatogenesis ENSG00000198793 ENSG00000145321 PMC9405571__F3 Multifaceted Roles of Autophagy in Infectious, Obstructive, and Malignant Airway Diseases ENSG00000162711 ENSG00000198793 ENSG00000112561 ENSG00000189403 ENSG00000001626 ENSG00000077463 ENSG00000145782 PMC10527326__F2 The Biomarkers, Molecular Targets and Mechanisms of Non-Alcoholic Steatohepatitis-Driven Hepatocarcinogenesis ENSG00000169047 ENSG00000168036 ENSG00000257727 ENSG00000079999 PMC8786701__F3 Impact of DNA testing on management of patients with colorectal cancer ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC4697456__F1 CAMP/protein kinase A signaling pathway in pathogenic basidiomycete fungi: Connections with iron homeostasis ENSG00000138433 ENSG00000177464 ENSG00000180644 PMC8698706__F10 Triple Isozyme Lactic Acid Dehydrogenase Inhibition in Fully Viable MDA-MB-231 Cells Induces Cytostatic Effects That Are Not Reversed by Exogenous Lactic Acid ENSG00000118007 ENSG00000108055 ENSG00000112118 ENSG00000073111 ENSG00000277273 ENSG00000117399 ENSG00000276876 ENSG00000093009 ENSG00000145604 ENSG00000101972 ENSG00000132646 ENSG00000115942 ENSG00000123374 PMC4413232__F10 Sonic Hedgehog signaling maintains proliferation/self-renewal of cerebellar progenitor cells ENSG00000198901 ENSG00000164690 PMC12073286__F8 Schematic diagram indicating how SP protects ALD mice via the multi-target regulation of the CYP2E1/Keap1/NFKB signaling pathway ENSG00000130649 ENSG00000079999 PMC3720830__F7 Cytochrome P450 1A1 Regulates Breast Cancer Cell Proliferation and Survival ENSG00000198793 PMC5085755__F3 Functions of three members of the UBXD protein family (UBXN1, P47, and FAF1) that are potentially involved in the prevention of cancer ENSG00000102871 ENSG00000162191 ENSG00000127191 ENSG00000185104 PMC10492287__F9 The metabolic pathway in placental cells ENSG00000125166 ENSG00000067057 ENSG00000086730 ENSG00000159399 PMC6098897__F2 Schematic diagram for the activation of BMPs, Wnt, and MAPK pathways by phytochemicals treatment ENSG00000178860 ENSG00000168036 PMC4114922__F5 Function and regulation of the Rho guanine nucleotide exchange factor Trio ENSG00000038382 ENSG00000157557 ENSG00000129910 ENSG00000135111 ENSG00000162692 PMC4114922__F6 Function and regulation of the Rho guanine nucleotide exchange factor Trio ENSG00000038382 PMC2556866__F1 Telomere structure and DSB processing ENSG00000175054 ENSG00000051180 PMC4114922__F4 Function and regulation of the Rho guanine nucleotide exchange factor Trio ENSG00000038382 ENSG00000010810 PMC4346946__F4 Regulatory mechanisms of actin dynamics in response to DNA damage ENSG00000152409 ENSG00000163914 ENSG00000182541 PMC8983706__F1 High-throughput translational profiling with riboPLATE-seq ENSG00000198793 PMC4346946__F3 DNA damage-induced molecular responses for DNA repair ENSG00000188486 ENSG00000149311 ENSG00000012048 PMC6330548__F2 The proposed genetic interactive network among genetic factors in lignin biosynthesis pathway, which exemplified by S‐lignin biosynthesis ENSG00000084774 ENSG00000132341 PMC9283012__F3 Insulin-Like Growth Factor 2 mRNA-Binding Protein 3 and Its Related Molecules as Potential Biomarkers in Small-Cell Lung Cancer ENSG00000104856 ENSG00000147202 ENSG00000281324 ENSG00000134215 ENSG00000158195 ENSG00000110931 ENSG00000167680 ENSG00000172007 ENSG00000155903 ENSG00000139625 ENSG00000102678 ENSG00000092820 ENSG00000078804 ENSG00000180210 ENSG00000169967 ENSG00000005893 ENSG00000007402 ENSG00000185008 ENSG00000168209 ENSG00000150594 ENSG00000276293 ENSG00000083290 ENSG00000106299 ENSG00000116741 ENSG00000274286 ENSG00000081189 ENSG00000196411 ENSG00000108179 ENSG00000177189 ENSG00000116106 ENSG00000100330 ENSG00000078579 ENSG00000010810 ENSG00000069849 ENSG00000136160 ENSG00000151617 ENSG00000115232 ENSG00000075213 ENSG00000182389 PMC8616433__F4 Glycyrrhizin as a Nitric Oxide Regulator in Cancer Chemotherapy ENSG00000189403 ENSG00000166278 ENSG00000146648 PMC10527059__F8 Presenilin-1-Derived Circular RNAs: Neglected Epigenetic Regulators with Various Functions in Alzheimer’s Disease ENSG00000141867 ENSG00000285109 ENSG00000198435 ENSG00000292167 ENSG00000205250 ENSG00000122565 ENSG00000273529 ENSG00000114315 ENSG00000132170 PMC6830879__F4 Schematic diagram showing the major regulatory growth factors released by exosomes and the changes in tendon that occur aiding the healing process ENSG00000167772 ENSG00000198793 ENSG00000111186 PMC8233804__F1 Is Vitamin D Deficiency Related to Increased Cancer Risk in Patients with Type 2 Diabetes Mellitus? ENSG00000111012 ENSG00000019186 ENSG00000135929 PMC11116266__F2 JAK STAT signaling proteins in spondyloarthropathy and possible mechanisms of action of the JAK inhibitors ENSG00000111537 PMC9117624__F3 Association Between Neddylation and Immune Response ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000172936 ENSG00000107201 ENSG00000131323 ENSG00000175104 ENSG00000276561 PMC3892798__F1 PD-1 in T-cell activation, exhaustion, and effector function ENSG00000134982 PMC6323445__F3 FGFR1/FGF21/BKlotho complex actions in the cardiomyocytes ENSG00000002330 ENSG00000105550 ENSG00000077782 PMC10527059__F4 Predicted function of miRNAs interacting with circPSEN1s is summarized in this picture ENSG00000116898 ENSG00000183153 ENSG00000182240 ENSG00000141576 ENSG00000205250 ENSG00000150457 ENSG00000283060 ENSG00000142279 ENSG00000172201 ENSG00000149503 PMC3774138__F1 Role of mTOR Inhibition in Preventing Resistance and Restoring Sensitivity to Hormone-Targeted and HER2-Targeted Therapies in Breast Cancer ENSG00000011566 ENSG00000002330 ENSG00000169047 ENSG00000284161 PMC4685736__F1 Tissue‐specific function of Blimp‐1 expression in dendritic cells ENSG00000167207 ENSG00000137265 ENSG00000145321 PMC7522539__F4 Mood stabilizers and mt protein or pathway targets, as well as the schematic of precision psychiatry medicine ENSG00000291355 ENSG00000141401 ENSG00000165119 ENSG00000124614 ENSG00000073578 ENSG00000109320 ENSG00000078369 ENSG00000198793 ENSG00000196591 ENSG00000170606 ENSG00000120885 ENSG00000171791 ENSG00000010256 ENSG00000164305 ENSG00000008083 ENSG00000132170 ENSG00000100290 ENSG00000117480 ENSG00000100302 ENSG00000010810 ENSG00000177606 ENSG00000115419 ENSG00000105723 ENSG00000182346 PMC3774138__F2 Role of mTOR Inhibition in Preventing Resistance and Restoring Sensitivity to Hormone-Targeted and HER2-Targeted Therapies in Breast Cancer ENSG00000002330 PMC7522539__F1 Conceptual systems framework in NPDs (BD/SZ/MD), and lithium treatment amelioration of mitochondrial (mt) functions in distinct pathways ENSG00000168036 PMC2654975__F1 Down-regulation of the Notch Pathway in Human Airway Epithelium in Association with Smoking and Chronic Obstructive Pulmonary Disease ENSG00000135547 ENSG00000140564 ENSG00000196782 ENSG00000196470 ENSG00000137845 ENSG00000144485 ENSG00000089692 ENSG00000143801 ENSG00000138613 ENSG00000184384 ENSG00000128917 ENSG00000283780 ENSG00000078747 ENSG00000069812 ENSG00000205155 ENSG00000196498 ENSG00000109670 ENSG00000135097 ENSG00000124257 ENSG00000184916 ENSG00000135144 ENSG00000090932 ENSG00000106003 ENSG00000091073 ENSG00000069869 ENSG00000197530 ENSG00000065526 ENSG00000153944 ENSG00000197959 ENSG00000183020 ENSG00000101346 ENSG00000273529 ENSG00000133961 ENSG00000186866 ENSG00000114315 ENSG00000101752 PMC3044403__F1 The GlcNAc and GalNAc salvage and O-GlcNAc signaling pathways ENSG00000147162 ENSG00000198408 ENSG00000156958 ENSG00000124357 PMC3680934__F1 Activation of TAZ upon epithelial-to-mesenchymal transition in human breast cancer cells ENSG00000186575 ENSG00000026508 ENSG00000150457 ENSG00000131023 PMC4026397__F2 Role of NADPH Oxidases in Liver Fibrosis ENSG00000188747 PMC2715000__F8 Summary of caspase 2-mediated signaling cascades in heat-induced germ cell apoptosis ENSG00000171791 ENSG00000007171 ENSG00000164949 PMC8345975__F1 Cardiomyocyte Proliferation as a Source of New Myocyte Development in the Adult Heart ENSG00000135446 ENSG00000250506 ENSG00000123374 ENSG00000105810 ENSG00000150457 ENSG00000131023 ENSG00000291442 ENSG00000178568 PMC5900062__F1 Canonical and non-canonical NFKB signaling pathways ENSG00000104856 ENSG00000109320 ENSG00000186716 ENSG00000197943 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000083799 ENSG00000154124 ENSG00000175104 ENSG00000127191 ENSG00000198286 PMC4810982__F1 Proposed scheme for the protective effects of linagliptin against ABeta-induced neuronal insulin signaling blockade.GLP-1 is synthesized and secreted by neuronal cells ENSG00000197635 ENSG00000096717 PMC3296242__F8 Models of interactions within the destruction complex (A) and the catalytic cycle of the destruction complex (B) ENSG00000134982 ENSG00000115266 ENSG00000168036 PMC4026397__F4 Role of NADPH Oxidases in Liver Fibrosis ENSG00000095739 ENSG00000125538 ENSG00000086991 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC4275033__F1 Metabolic pathways that lead to the production of fatty acids and fatty acid-derived chemicals ENSG00000168040 ENSG00000106546 PMC5342869__F1 Regulation of the Hippo-YAP pathway by extracellular biophysical cues ENSG00000291507 ENSG00000163914 ENSG00000111371 ENSG00000150457 ENSG00000103257 ENSG00000131023 PMC2997573__F1 The current understanding of PELP1 signaling pathway ENSG00000168066 ENSG00000291971 ENSG00000138798 ENSG00000146648 ENSG00000141456 PMC4346946__F1 Nuclear entry of Cofilin-1 (CFL-1) via various stresses ENSG00000106683 ENSG00000128908 ENSG00000182541 PMC6160231__F3 Phospho-proteomic analysis of primary human colon epithelial cells during the early Trypanosoma cruzi infection phase ENSG00000291971 ENSG00000010810 ENSG00000060237 ENSG00000168036 PMC4226441__F2 Targeting the estrogen pathway for the treatment and prevention of lung cancer ENSG00000163235 ENSG00000291971 ENSG00000113070 ENSG00000146648 PMC11945810__F1 Possible mechanism underlying hepatotoxicity ENSG00000171759 ENSG00000062485 PMC4553092__F1 The roles of various key members of the LRP receptor family; LRP4, LRP5, LRP6 and LRP8 in bone related traits and bone mass regulation ENSG00000281324 ENSG00000162337 ENSG00000134569 ENSG00000157193 ENSG00000183762 PMC11945810__F2 Illustration of cell crosstalk and molecular pathways of different chemicals in the liver microenvironment ENSG00000171759 ENSG00000106546 PMC10041467__F1 Pathological Effects of Circulating Hydrophobic Bile Acids in Alzheimer’s Disease ENSG00000242110 ENSG00000276559 ENSG00000167910 ENSG00000135929 PMC4962009__F1 Replicative aging cooperates with other aging mechanisms to activate the p53 and/or Rb signaling pathways ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC8446424__F2 TREM2: Keeping Pace With Immune Checkpoint Inhibitors in Cancer Immunotherapy ENSG00000198793 ENSG00000168036 PMC7202281__F5 Interaction network of differentially expressed proteins between patients with pancreatic cancer and healthy controls, assessed by the Ingenuity Pathway Analysis software ENSG00000149311 ENSG00000197956 ENSG00000128322 ENSG00000123416 ENSG00000105329 ENSG00000143815 ENSG00000131747 ENSG00000141753 ENSG00000120868 ENSG00000037280 ENSG00000128564 PMC2721821__F6 Graphical representation of the Hh signaling pathway in its activated state and possible sites of HPI action ENSG00000164690 ENSG00000128602 PMC3205612__F1 Interplay between autophagy and intracellular pathogens ENSG00000177169 ENSG00000111537 ENSG00000083290 ENSG00000126775 ENSG00000198793 PMC10346484__F2 Key metabolic pathways for the biosynthesis of NEAAs, the enzymes in each pathway, and the main functions of each AA [54,173] ENSG00000125166 ENSG00000135423 ENSG00000111237 ENSG00000198793 ENSG00000132840 ENSG00000038002 ENSG00000146733 ENSG00000070669 ENSG00000116984 ENSG00000284320 ENSG00000171759 ENSG00000182551 ENSG00000166123 ENSG00000167701 PMC7568652__F3 CD40 pathway genes upregulated (red) or downregulated (green) by exposure of primary human keratinocytes to TSST-1 (100 μg/ml) or SEB (100 μg/ml) in triplicate assays for 6 h exposure time ENSG00000082512 ENSG00000056558 ENSG00000131323 ENSG00000175104 ENSG00000123268 PMC7568652__F4 CNTF pathway genes upregulated (red) or downregulated (green) by exposure of primary human keratinocytes to TSST-1 (100 μg/ml) or SEB (100 μg/ml) in triplicate assays for 6 h exposure time ENSG00000242689 ENSG00000122756 ENSG00000198793 PMC7553775__F7 Coordinated repression of A3B transcription by both E2F4/DREAM and E2F6/PRC1.6 complexes ENSG00000156374 ENSG00000281766 ENSG00000103479 ENSG00000114126 ENSG00000198176 ENSG00000015153 ENSG00000162521 ENSG00000267796 ENSG00000174197 ENSG00000205250 ENSG00000189308 ENSG00000080839 PMC10296091__F1 A2AR effects in microglia, astrocytes, and synapses under physiological conditions PMC10751873__F2 High expression level of CRNDE contributes to CRC by upregulating the signaling pathways such as Ras/MAPK, Wnt/Beta-catenin ENSG00000156802 ENSG00000138166 ENSG00000168036 ENSG00000214753 ENSG00000124762 PMC9523377__F3 Multifunctionality of Calebin A in inflammation, chronic diseases and cancer ENSG00000168610 ENSG00000121966 PMC6101248__F6 BPS-induced placental dysfunction working model ENSG00000137270 ENSG00000068001 PMC6928850__F1 Molecular Characterization of XX Maleness ENSG00000143355 ENSG00000172893 ENSG00000118526 ENSG00000168036 ENSG00000100146 ENSG00000102678 ENSG00000170370 ENSG00000125398 ENSG00000137090 ENSG00000005513 ENSG00000100625 ENSG00000140443 ENSG00000162552 ENSG00000169218 ENSG00000104899 ENSG00000171105 ENSG00000285109 ENSG00000143842 ENSG00000134363 ENSG00000134595 ENSG00000166278 ENSG00000168066 ENSG00000135409 ENSG00000126778 ENSG00000127948 PMC8534102__F3 Mental Illness and Amyloid: A Scoping Review of Scientific Evidence over the Last 10 Years (2011 to 2021) ENSG00000142192 PMC4814919__F9 Beta-TrCP-mediated ubiquitination and degradation of liver-enriched transcription factor CREB-H ENSG00000110244 ENSG00000105550 PMC3310155__F1 Model of CaS receptor sorting traffic ENSG00000132329 ENSG00000036828 PMC6617847__F5 Schematic outline of the salinity-induced response pathway based on proteome, gene expression, and physiological changes in chickpea leaves ENSG00000136997 PMC10751873__F4 CRNDE: A Pivotal Oncogenic Long Non-Coding RNA in Cancers ENSG00000134057 ENSG00000135446 ENSG00000168036 ENSG00000105810 PMC10751873__F5 CRNDE: A Pivotal Oncogenic Long Non-Coding RNA in Cancers ENSG00000112242 ENSG00000073921 ENSG00000124193 PMC4918703__F1 The podocyte and the glomerular filtration barrier (GFB) ENSG00000138639 ENSG00000203485 ENSG00000198087 ENSG00000100345 ENSG00000130402 ENSG00000137672 PMC8151307__F10 Quo vadis Cardiac Glycoside Research? ENSG00000291971 ENSG00000146648 PMC7023272__F2 Resveratrol (RES) crosses the blood‒brain barrier via tight junctions ENSG00000198793 ENSG00000170430 ENSG00000168610 PMC3526508__F2 Becoming a follicular or a MZ B-cell? ENSG00000186716 ENSG00000010671 PMC6429457__F4 Upstream regulator analysis of the differential proteome of the spleen from 11-week Npc1−/− mice ENSG00000129515 ENSG00000197629 ENSG00000100985 ENSG00000136235 ENSG00000169919 ENSG00000100721 ENSG00000159189 PMC6451240__F1 Phagocytic pathway in glial cells ENSG00000167601 ENSG00000168329 ENSG00000132718 ENSG00000203710 ENSG00000069329 ENSG00000145794 ENSG00000173578 ENSG00000136869 ENSG00000084733 PMC4167320__F1 Overview of the extrinsic, intrinsic, and phagocytosis-induced apoptotic pathways ENSG00000132906 ENSG00000132646 ENSG00000164305 PMC8072665__F4 Identification of the Key Role of NFKB Signaling Pathway in the Treatment of Osteoarthritis With Bushen Zhuangjin Decoction, a Verification Based on Network Pharmacology Approach ENSG00000169248 ENSG00000100591 ENSG00000168925 ENSG00000288174 ENSG00000169710 ENSG00000124107 ENSG00000145386 ENSG00000112715 ENSG00000118777 ENSG00000178726 ENSG00000104368 ENSG00000163631 ENSG00000117525 ENSG00000136997 ENSG00000166501 ENSG00000095303 ENSG00000123374 ENSG00000108821 ENSG00000120251 ENSG00000282899 ENSG00000087245 ENSG00000177575 ENSG00000189058 ENSG00000081041 ENSG00000106333 ENSG00000007908 ENSG00000213341 ENSG00000257335 ENSG00000166670 ENSG00000125347 ENSG00000132170 ENSG00000108839 ENSG00000169245 ENSG00000118785 ENSG00000170458 ENSG00000005381 ENSG00000131196 PMC8072665__F5 Identification of the Key Role of NFKB Signaling Pathway in the Treatment of Osteoarthritis With Bushen Zhuangjin Decoction, a Verification Based on Network Pharmacology Approach ENSG00000291931 ENSG00000160789 ENSG00000105401 ENSG00000073111 ENSG00000012048 ENSG00000173369 ENSG00000168283 ENSG00000134086 ENSG00000136997 ENSG00000149273 ENSG00000139687 ENSG00000140464 ENSG00000280548 ENSG00000187531 ENSG00000142192 ENSG00000170027 ENSG00000164587 ENSG00000108773 ENSG00000135473 ENSG00000142534 ENSG00000100345 ENSG00000167658 ENSG00000101361 ENSG00000177954 ENSG00000278270 ENSG00000172809 ENSG00000132646 ENSG00000130726 ENSG00000100591 ENSG00000181163 ENSG00000165280 ENSG00000171863 ENSG00000129351 ENSG00000180210 ENSG00000125691 ENSG00000150991 ENSG00000131876 ENSG00000071082 ENSG00000149269 ENSG00000132383 ENSG00000123374 ENSG00000185591 ENSG00000050405 ENSG00000253729 ENSG00000100603 ENSG00000005339 ENSG00000173039 ENSG00000187522 ENSG00000162385 ENSG00000065978 ENSG00000177606 ENSG00000074266 ENSG00000141367 ENSG00000114166 PMC3545710__F5 Suggested pathway ENSG00000137193 ENSG00000168610 ENSG00000131196 PMC6226322__F7 ZFPM2-AS1, a Novel lncRNA, Attenuates the p53 Pathway and Promotes Gastric Carcinogenesis by Stabilizing MIF PMC6928850__F2 Testicular and ovotesticular differentiation in XX foetuses ENSG00000162552 ENSG00000169218 ENSG00000104899 ENSG00000125398 ENSG00000168066 ENSG00000137090 ENSG00000135409 ENSG00000134595 ENSG00000102678 ENSG00000100146 PMC9094073__F1 Targeting mTOR and eIF4E: a feasible scenario in ovarian cancer therapy PMC6387020__F6 Representative liver disease pathway ENSG00000132906 ENSG00000002330 ENSG00000116044 ENSG00000109320 ENSG00000102871 ENSG00000198793 ENSG00000173039 ENSG00000171791 ENSG00000127191 ENSG00000164305 ENSG00000079999 ENSG00000291983 ENSG00000100985 ENSG00000146648 PMC7564998__F1 Oxidative stress, mitochondrial dysfunction, axonal transport, and glutamate excitotoxicity in amyotrophic lateral sclerosis (ALS) ENSG00000107290 ENSG00000204842 ENSG00000123240 ENSG00000100285 ENSG00000165280 PMC6387020__F5 Representative cardiovascular disease pathway ENSG00000132906 ENSG00000002330 ENSG00000070831 ENSG00000291971 ENSG00000095303 ENSG00000073756 PMC8922476__F3 Gut-brain axis of CCM disease ENSG00000127528 ENSG00000136869 ENSG00000114209 ENSG00000136826 PMC3408345__F6 Glucocorticoid (GC) actions in the airways epithelium ENSG00000109819 ENSG00000213928 ENSG00000115415 ENSG00000276561 PMC1199368__F5 Candidate genes that are involved with the metabolism of androgen and estrogen ENSG00000108786 ENSG00000129214 ENSG00000196620 ENSG00000203857 PMC2885703__F11 WNT1-Inducible Signaling Pathway Protein-1 Activates Diverse Cell Survival Pathways and Blocks Doxorubicin-induced Cardiomyocyte Death ENSG00000168036 PMC4017675__F5 In sum, there is a critical clinical need for better understanding and treatment of inflammatory airway disease in general, and mucous cell metaplasia in particular ENSG00000291363 ENSG00000117983 PMC2896964__F1 Schematic representation of the possible interactions between HIV-1 and the host miRNA-guided RNA silencing pathway ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC3830884__F4 MAP kinase signaling pathway of sugarcane infected by S ENSG00000070831 PMC11999627__F2 IL-33/ST2 signaling pathway ENSG00000137033 ENSG00000172936 ENSG00000157625 ENSG00000185187 ENSG00000175104 ENSG00000184216 ENSG00000115594 PMC6482944__F2 Molecular regulation of PFGA in Mice ENSG00000104899 ENSG00000157404 ENSG00000107562 ENSG00000164404 ENSG00000133116 ENSG00000198793 ENSG00000128342 PMC5938816__F11 Gene expression pattern related to TLR4 signaling pathway following epileptic seizure ENSG00000172936 ENSG00000136869 PMC3797650__F1 Diagram of hedgehog (Hh) signaling in mammalian cells ENSG00000168283 ENSG00000156076 ENSG00000112210 ENSG00000078747 ENSG00000144857 ENSG00000166813 ENSG00000138798 ENSG00000171791 ENSG00000128602 ENSG00000118777 ENSG00000168610 ENSG00000281857 PMC3959213__F6 Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway ENSG00000074800 PMC11545656__F1 Scheme of CD95 pathway ENSG00000120868 ENSG00000168040 PMC4581331__F4 Biological mechanisms of MALAT1 in CRC ENSG00000168036 PMC11545656__F2 Scheme of CD95-mediated apoptotic and non-apoptotic signaling ENSG00000137275 ENSG00000168040 ENSG00000127191 PMC3959213__F1 Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway ENSG00000074800 PMC4143117__F7 Dynamics of BMP Signaling in Limb Bud Mesenchyme and Polydactyly ENSG00000139219 ENSG00000112280 ENSG00000125398 PMC3578363__F4 Targeting ubiquitin-dependent degradation of CDK inhibitors ENSG00000145604 ENSG00000113558 ENSG00000123374 PMC3578363__F1 G1 cell cycle control by the pRB pathway ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC2396785__F2 Physiologic properties and regulation of the actin cytoskeleton in vascular smooth muscle ENSG00000070831 ENSG00000291971 ENSG00000163914 PMC5171903__F9 GALNT14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment ENSG00000124766 ENSG00000077782 PMC6964670__F2 Analysing IDO1 inhibitors clinical trial results ENSG00000111537 ENSG00000262635 ENSG00000188676 ENSG00000106546 PMC5834400__F1 Apoptotic signaling through the tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) pathway ENSG00000171791 ENSG00000168040 PMC5832419__F5 Glucose metabolism and NRF2 coordinate the antioxidant response in melanoma resistant to MAPK inhibitors ENSG00000211445 ENSG00000173599 ENSG00000023909 PMC3844062__F2 Proposed pathway for NLRP3 inflammasome activation during viral respiratory tract infection ENSG00000162711 ENSG00000125538 PMC6240570__F1 Gastric Cancer Stem Cells: Mechanisms and Therapeutic Approaches ENSG00000134982 ENSG00000168036 ENSG00000128602 PMC7503838__F11 Therapeutic targets for brain injury for nanoparticle mediated drug delivery ENSG00000214285 PMC8787930__F1 Exosome-liposome hybrid nanoparticle codelivery of TP and miR497 conspicuously overcomes chemoresistant ovarian cancer ENSG00000173599 PMC2810509__F3 BIOLOGY OF VASCULAR MALFORMATIONS OF THE BRAIN ENSG00000170365 PMC7693462__F5 NAA and citrate pathways to acetyl-CoA ENSG00000131473 ENSG00000185818 PMC3338129__F2 Crosstalk Between Reverse Cholesterol Transport and Innate Immunity ENSG00000174125 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000160179 ENSG00000168610 ENSG00000164342 PMC7693462__F6 NAA as a selective, alternative cytoplasmic and nuclear acetyl-CoA source ENSG00000131473 ENSG00000185818 ENSG00000079432 PMC11557815__F3 Impact of P ENSG00000261371 ENSG00000161921 ENSG00000141052 PMC7876332__F7 Scheme about the central role of erianin in ferroptosis induction and migration inhibition ENSG00000135446 ENSG00000198793 ENSG00000123374 PMC8112288__F1 Insights on the mechanisms of action of ozone in the medical therapy against COVID-19 ENSG00000178573 ENSG00000079999 PMC9220264__F3 Focus on the Contribution of Oxidative Stress in Skin Aging ENSG00000181019 PMC3675894__F2 Summary of association of genetic alterations of the HH pathway and cancer type ENSG00000164690 ENSG00000128602 PMC2496917__F1 Interfering the PI3K/mTOR/p70S6K signaling pathway ENSG00000124102 ENSG00000198793 PMC2871738__F2 Molecular determinants of mitochondrial quality-control networks ENSG00000133895 ENSG00000188554 ENSG00000116688 ENSG00000115307 ENSG00000214253 PMC2871738__F3 Role of the major PD-associated genes in mitochondrial dysfunction ENSG00000175193 ENSG00000158828 PMC6710038__F7 Schematic model of the mechanism that MIR210HG promotes tumorigenesis and metastasis through a ceRNA pattern in IBC patients PMC6377292__F1 Transcriptional and epigenetic regulation of microglia in health and disease ENSG00000103811 ENSG00000182578 ENSG00000167601 ENSG00000103449 ENSG00000168329 ENSG00000159216 ENSG00000204103 ENSG00000261857 ENSG00000140968 ENSG00000157601 ENSG00000081189 ENSG00000276561 PMC10542901__F1 Endothelium as initiator and target of type I IFN responses ENSG00000169245 ENSG00000183735 ENSG00000213928 ENSG00000164430 ENSG00000115415 ENSG00000125347 PMC9315706__F1 Autophagy: A Key Player in Pancreatic Cancer Progression and a Potential Drug Target ENSG00000177169 ENSG00000110497 ENSG00000123395 ENSG00000198382 ENSG00000144848 ENSG00000171791 ENSG00000145782 PMC6359907__F4 Selective autophagy as a potential therapeutic target for neurodegenerative disorders ENSG00000081913 ENSG00000112561 ENSG00000145782 PMC9315706__F5 Autophagy: A Key Player in Pancreatic Cancer Progression and a Potential Drug Target ENSG00000177169 ENSG00000110497 ENSG00000123395 ENSG00000083290 PMC3675657__F7 Mechanisms for iron-dependent and iron-independent IRP2 regulation ENSG00000100387 ENSG00000118564 ENSG00000113558 PMC5402004__F10 Schematic signal transduction network representing the observed changes in protein and lipid metabolism in eWAT during sepsis-recovery ENSG00000177169 ENSG00000162711 ENSG00000128272 ENSG00000144895 ENSG00000145782 ENSG00000057663 PMC6770250__F1 Basics of transforming growth factor B (TGFB) signaling ENSG00000157933 PMC6770250__F2 TGFB signaling in cholangiocarcinoma (CCA) progression ENSG00000162433 PMC2810509__F2 BIOLOGY OF VASCULAR MALFORMATIONS OF THE BRAIN ENSG00000163914 ENSG00000150093 PMC6401655__F1 Subcellular localization and function of the eukaryotic LSM complexes ENSG00000236826 ENSG00000170860 ENSG00000130332 ENSG00000130520 ENSG00000164167 PMC9643504__F3 Hippo signalling pathway and its implications in human health and diseases ENSG00000087095 ENSG00000126016 ENSG00000186575 ENSG00000183853 ENSG00000181788 PMC9643504__F2 Hippo signalling pathway and its implications in human health and diseases ENSG00000113645 ENSG00000047644 ENSG00000197905 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000151718 ENSG00000074219 PMC8065698__F2 UPR drives pro-inflammatory responses to ER stress ENSG00000167207 ENSG00000144895 ENSG00000172936 ENSG00000136869 ENSG00000100219 ENSG00000127191 ENSG00000106100 PMC9059347__F1 Constellation of cholesterol-dependent processes associated with SARS-CoV-2 infection ENSG00000130164 ENSG00000075239 PMC5389695__F3 SUMO as a regulator of PCNA ubiquitylation and repair pathway choice ENSG00000132646 ENSG00000070950 PMC6042961__F10 FRMD8 stabilises the iRhom2/ADAM17 sheddase complex at the cell surface ENSG00000146648 PMC3024260__F1 Computational and Experimental Study of the Regulatory Mechanisms of the Complement System ENSG00000173599 ENSG00000244731 ENSG00000166278 ENSG00000132693 ENSG00000236625 PMC8510680__F6 SETD7 regulates chondrocyte differentiation and glycolysis via the Hippo signaling pathway and HIF-1A ENSG00000125398 ENSG00000131023 ENSG00000145391 PMC8486678__F1 Clinical drug therapies and biologicals currently used or in clinical trial to treat COVID-19 ENSG00000130234 ENSG00000184012 PMC8073279__F1 Periconceptional Multivitamin Supplementation on Folate and Homocysteine Levels Depending on Genetic Variants of Methyltetrahydrofolate Reductase in Infertile Japanese Women ENSG00000228716 PMC3656432__F4 Myostatin (Mstn) pathway PMC4928187__F2 Map of lipid metabolic pathways in C ENSG00000173599 ENSG00000198670 ENSG00000099810 ENSG00000099194 ENSG00000184207 PMC9406587__F3 Proteostasis Deregulation in Neurodegeneration and Its Link with Stress Granules: Focus on the Scaffold and Ribosomal Protein RACK1 ENSG00000128272 ENSG00000198793 ENSG00000100219 PMC7677084__F9 Network diagram of two pivotal pathways for muscle development in KEGG enrichment analysis ENSG00000087095 ENSG00000107404 ENSG00000138795 ENSG00000137673 ENSG00000170214 ENSG00000116741 ENSG00000002745 ENSG00000101306 ENSG00000182621 ENSG00000118971 ENSG00000081189 ENSG00000101892 ENSG00000095739 ENSG00000100387 ENSG00000131196 PMC11496173__F4 Molecular mechanisms of Keap1-dependent and Keap1-independent modulation of Nrf2 ENSG00000178573 ENSG00000091140 ENSG00000079999 PMC11496173__F5 Probable mechanism of action of ISL on the Nrf2 pathway ENSG00000162711 ENSG00000181019 ENSG00000096717 ENSG00000079999 PMC5727596__F2 Influence of chosen compounds/proteins on the Wnt signaling pathway which are under consideration as either potential therapeutic targets (continuous line) or potential therapeutic/adjuvant agents (dotted line) ENSG00000149269 PMC3983869__F1 Beta-Catenin is a multifunctional protein that localizes at cell-cell contacts, the nucleus, cytosol and centrosomes ENSG00000134982 ENSG00000168036 PMC10310354__F2 Function of Akkermansia muciniphila in type 2 diabetes and related diseases PMC10389837__F3 Research Progress on the Etiology and Pathogenesis of Alzheimer's Disease from the Perspective of Chronic Stress PMC4026077__F1 Inhibition of hedgehog signaling on cell growth and migration of uveal melanoma cells ENSG00000106571 ENSG00000164161 ENSG00000136997 ENSG00000128602 PMC9603545__F1 Wnt Signaling and Aging of the Gastrointestinal Tract ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3960487__F2 Signaling pathways involved in YPP regulation ENSG00000164327 PMC2714639__F6 MT1-MMP expression in first trimester trophoblasts is stimulated by insulin, IGF1 and IGF2 by different signalling pathways ENSG00000140443 PMC7693462__F4 Hypothesized role of NAA in cancer cells as an alternative source of acetyl-CoA for specific transcription factor acetylation in place of citrate ENSG00000131473 ENSG00000185818 ENSG00000096717 ENSG00000062485 PMC8166058__F5 Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer ENSG00000115904 ENSG00000166068 ENSG00000196712 PMC9273332__F1 Single-cell deletion analyses show control of pro-T cell developmental speed and pathway by Tcf7, Spi1, Gata3, Bcl11a, Erg, and Bcl11b ENSG00000157554 ENSG00000157404 ENSG00000066336 ENSG00000078399 ENSG00000026508 ENSG00000107485 ENSG00000174483 ENSG00000112186 ENSG00000143995 PMC3328302__F7 Schematic diagram illustrating the proposed interaction between CDH17 and Wnt/Beta-catenin pathway during HCC progression ENSG00000134982 ENSG00000132646 ENSG00000168036 PMC5768892__F6 Gcn5−/− EBs becomes evident early during EB differentiation ENSG00000065911 ENSG00000171105 ENSG00000060982 ENSG00000106070 ENSG00000136997 ENSG00000157064 ENSG00000168610 ENSG00000116649 ENSG00000178445 ENSG00000187678 PMC8946903__F12 Spermatozoal Mitochondrial Dynamics Markers and Other Functionality-Related Signaling Molecules Exert Circadian-like Response to Repeated Stress of Whole Organism ENSG00000109819 ENSG00000185386 ENSG00000050748 ENSG00000116688 ENSG00000158828 ENSG00000112561 ENSG00000188130 ENSG00000166484 ENSG00000069956 ENSG00000175567 ENSG00000106459 ENSG00000214253 PMC2705999__F3 Castration-Adapted Prostate Cancer: Targeting Androgen Metabolic Pathways in Recurrent Disease ENSG00000197888 ENSG00000196620 ENSG00000187134 PMC209413__F1 The TGF-&bgr;/Smad pathway and its interrelationship with mediators of inflammatory signals ENSG00000167207 ENSG00000115415 PMC8824786__F1 Functional TGFB1 polymorphism in the donor associates with long-term graft survival after kidney transplantation PMC9066914__F6 EGF signaling promotes the lineage conversion of astrocytes into oligodendrocytes ENSG00000134982 ENSG00000138798 ENSG00000205927 ENSG00000100146 ENSG00000146648 PMC5851616__F9 Tilianin improved myocardial apoptosis ENSG00000115317 PMC6714585__F1 Hedgehog signaling pathway ENSG00000106571 ENSG00000136997 ENSG00000164690 ENSG00000128602 PMC11585128__F7 Secondary BAs regulate liver TH17/Treg cell differentiation to maintain NASH tolerance ENSG00000125740 ENSG00000276559 ENSG00000198851 ENSG00000163220 ENSG00000113161 ENSG00000049768 ENSG00000174607 ENSG00000198203 ENSG00000162594 ENSG00000177606 ENSG00000180432 ENSG00000026508 ENSG00000115271 ENSG00000175104 ENSG00000023839 PMC4231374__F1 Hypothetical representation of PI3K/AKT/PTEN signaling in pancreatic Beta-cells is shown, which modulate NOXs-derived reactive oxygen species (ROS) generation ENSG00000198793 ENSG00000168036 PMC8598044__F1 Host Innate Immunity Against Hepatitis Viruses and Viral Immune Evasion ENSG00000088888 ENSG00000175104 PMC7474398__F6 Distribution of target proteins of the QX1 formula on the integrated “cardiac disease-related pathway.” The cardiac disease-related pathway contained calcium, MAPK, PI3K/AKT, and Toll-like receptor signaling pathways ENSG00000002330 ENSG00000138798 ENSG00000105656 ENSG00000213341 ENSG00000171791 ENSG00000150455 ENSG00000127191 ENSG00000087460 ENSG00000007171 ENSG00000159921 ENSG00000170458 ENSG00000177606 ENSG00000136997 ENSG00000125538 ENSG00000136869 ENSG00000172936 ENSG00000175104 ENSG00000146648 PMC8189631__F6 NRF2 induction via FAM129B in mutant BRAF cells ENSG00000181019 ENSG00000051180 ENSG00000023909 ENSG00000132963 ENSG00000197063 ENSG00000079999 PMC8598044__F2 Host Innate Immunity Against Hepatitis Viruses and Viral Immune Evasion ENSG00000183735 ENSG00000239732 ENSG00000088888 ENSG00000115415 PMC8598044__F3 Host Innate Immunity Against Hepatitis Viruses and Viral Immune Evasion ENSG00000183735 ENSG00000088888 PMC8598044__F4 Host Innate Immunity Against Hepatitis Viruses and Viral Immune Evasion ENSG00000213928 ENSG00000105397 PMC7471444__F5 Comparative pharmacogenomic analysis of three classic TCM prescriptions for coronary heart disease based on molecular network modeling ENSG00000150991 ENSG00000100979 ENSG00000165269 PMC8469349__F7 Wharton’s Jelly-Derived Mesenchymal Stem Cells Reduce Fibrosis in a Mouse Model of Duchenne Muscular Dystrophy by Upregulating microRNA 499 ENSG00000198947 PMC545911__F1 Phosphoinositide kinase specific genetic interactions ENSG00000149823 ENSG00000120805 ENSG00000143761 ENSG00000204070 ENSG00000006715 PMC8818945__F10 Neuroprotective Effects of Omentin-1 Against Cerebral Hypoxia/Reoxygenation Injury via Activating GAS6/Axl Signaling Pathway in Neuroblastoma Cells ENSG00000181019 ENSG00000171791 PMC1698524__F5 Model linking HSP70 induction to p33ING1b-induced apoptosis ENSG00000102871 ENSG00000168040 ENSG00000132341 PMC8629365__F2 Schematic presentation of local translation regulation in dendritic spines of glutamatergic synapses of hippocampal pyramidal cells in response to synapse stimulation PMC5882662__F6 Metabolic pathways related to the differential metabolites identified in the BDE-3 groups ENSG00000157184 ENSG00000159224 PMC4399989__F8 Programming of Obesity and Comorbidities in the Progeny: Lessons from a Model of Diet-Induced Obese Parents ENSG00000042832 ENSG00000026103 PMC9536090__F5 Differential modulation of cancer‐related genes by mitochondrial DNA haplogroups and the STING DNA sensing system ENSG00000012048 ENSG00000146648 PMC11079208__F5 Mapping the function of MicroRNAs as a critical regulator of tumor-immune cell communication in breast cancer and potential treatment strategies ENSG00000100234 ENSG00000078098 ENSG00000168610 ENSG00000140416 PMC11079208__F3 HER-2/EGFR signaling pathway in breast cancer ENSG00000146648 PMC6449624__F2 BTLA-associated signaling pathways (stimulatory/inhibitory) regulate the outcomes of HBV-ACLF, liver graft tolerance/rejection, liver cirrhosis and hepatocellular carcinoma PMC3413220__F1 LCAT functions potentially affecting the pathogenesis of cardiovascular disease ENSG00000160179 PMC7230342__F4 2-step DSB repair pathway choice model [,,] ENSG00000149311 ENSG00000051180 ENSG00000139618 PMC12213698__F1 Basics of the canonical Wnt signaling pathway ENSG00000111537 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000125538 ENSG00000168036 ENSG00000113520 PMC12213698__F2 Basics of the noncanonical Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC2788255__F6 Wnt signalling pathway downregulated in osteosarcoma ENSG00000087095 ENSG00000107404 ENSG00000138795 ENSG00000134982 ENSG00000174804 ENSG00000168036 ENSG00000157240 ENSG00000163558 ENSG00000067606 ENSG00000177606 ENSG00000136997 ENSG00000104290 ENSG00000165879 ENSG00000161202 ENSG00000119402 ENSG00000155760 PMC6580171__F4 Human intermuscular adipose tissue (IMAT) revealed a downregulation of key pathways associated with insulin resistance ENSG00000213928 ENSG00000073578 ENSG00000130414 ENSG00000261857 ENSG00000138798 ENSG00000114737 ENSG00000198793 ENSG00000115904 ENSG00000171791 ENSG00000118971 ENSG00000138356 ENSG00000179295 ENSG00000122756 ENSG00000184752 ENSG00000136997 ENSG00000164400 ENSG00000022267 ENSG00000005339 ENSG00000242689 ENSG00000179091 ENSG00000138495 ENSG00000137193 ENSG00000131095 ENSG00000004779 ENSG00000105639 ENSG00000178127 ENSG00000143252 ENSG00000183648 ENSG00000131174 ENSG00000115415 ENSG00000186010 ENSG00000171608 PMC4167640__F2 Two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment ENSG00000129474 ENSG00000132471 ENSG00000126016 ENSG00000186575 ENSG00000064393 ENSG00000163914 ENSG00000114978 ENSG00000132849 ENSG00000131023 PMC4167640__F1 Two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment ENSG00000114978 ENSG00000150457 ENSG00000131023 PMC11040299__F1 Autolysosomal acidification impairment as a mediator for TNFR1 induced neuronal necroptosis in Alzheimer's disease ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC11603026__F4 Drug repurposing discovery in Mpox infection ENSG00000156127 PMC5552148__F2 Generation of ROS as a result of incident radiation affecting the mitochondrion.Notes: ROS have been shown to form oxidative DNA adducts, such as 8-OHdG, which in turn can lead to base modifications and transversions, such as GC to TA ENSG00000149311 ENSG00000175054 PMC7188831__F3 Adaptors of Salmonella autophagy ENSG00000158717 ENSG00000183735 ENSG00000123240 PMC5925168__F2 Pruritic signaling pathways ENSG00000104321 ENSG00000078747 ENSG00000149782 ENSG00000172938 ENSG00000196689 PMC4935219__F1 Cellular and molecular targets of MTX, 5FU and irinotecan in the small intestine of the AT ENSG00000165556 ENSG00000019991 ENSG00000090402 ENSG00000285109 PMC11821285__F2 Proposed molecular mechanism of ARI in cancer involving modulation of Hippo signaling and Wnt signaling pathway ENSG00000134982 ENSG00000168036 ENSG00000131023 PMC11821285__F3 Proposed pathways and molecular interactions for ARI's anticancer effects ENSG00000291971 ENSG00000198793 ENSG00000161202 ENSG00000135914 ENSG00000168610 PMC7998946__F2 Metabolism of activated T cell and the effect of cancer-induced tumor microenvironment (TME) acidification on T cell response ENSG00000159399 PMC11603026__F5 Mpox’s role in antiviral and proviral cell signaling regulation ENSG00000164430 ENSG00000104237 ENSG00000197601 ENSG00000026103 PMC11603026__F6 Mpox manipulation and activation of proviral signaling via AKT, Wnt, and STAT3 signaling pathways ENSG00000183735 ENSG00000002330 ENSG00000135446 ENSG00000064393 ENSG00000177606 ENSG00000134070 ENSG00000127191 ENSG00000168610 ENSG00000026103 PMC2787730__F10 TNF- A–inducible genes that were specifically downregulated after DC treatment but not by C95 curcumin: the focal adhesion pathway ENSG00000010810 PMC9561344__F1 Treatment of myocardial interstitial fibrosis in pathological myocardial hypertrophy ENSG00000108691 PMC2787730__F11 TNF- A–inducible genes that were specifically downregulated after DC treatment but not by C95 curcumin: the apoptosis pathway ENSG00000149311 ENSG00000002330 ENSG00000102871 ENSG00000172936 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC2787730__F12 TNF- A–inducible genes that were specifically downregulated after DC treatment but not by C95 curcumin: the cell-adhesion pathway ENSG00000149564 ENSG00000169896 ENSG00000090863 ENSG00000081237 ENSG00000134982 ENSG00000197471 ENSG00000163599 ENSG00000150093 ENSG00000007908 ENSG00000150637 ENSG00000292348 ENSG00000116815 ENSG00000261371 ENSG00000188404 ENSG00000154721 ENSG00000162692 ENSG00000076662 ENSG00000115232 ENSG00000139626 PMC3969740__F2 A) Pathogen recognition receptors RIG-I and TLR3 detect HCV ds RNA and activate via their adaptor molecules IPS-1 and TRIF ENSG00000213928 ENSG00000144895 ENSG00000276561 ENSG00000164342 PMC4383314__F3 Serum starvation induces changes to cellular metabolism and chromatin remodeling proteins ENSG00000149084 ENSG00000112972 ENSG00000181163 ENSG00000172893 ENSG00000159259 ENSG00000167508 ENSG00000105607 ENSG00000164104 ENSG00000171720 ENSG00000133895 ENSG00000103510 ENSG00000066135 ENSG00000004779 ENSG00000100888 ENSG00000126012 ENSG00000160752 ENSG00000117724 ENSG00000288210 ENSG00000292086 ENSG00000121481 ENSG00000134824 ENSG00000161533 ENSG00000141570 ENSG00000102974 ENSG00000149480 PMC9500245__F6 Decreased GZMB, NRP1, ITPR1, and SERPINB9 Transcripts Lead to Reduced Regulatory T Cells Suppressive Capacity in Generalized Vitiligo Patients ENSG00000049768 PMC10040598__F1 The inflammasome in insulin resistance and type 2 diabetes mellitus ENSG00000169047 ENSG00000198793 PMC8630042__F1 RAS/MAPK pathway downstream signaling and therapeutic targets ENSG00000198793 ENSG00000126458 ENSG00000196712 PMC5365060__F3 Biosynthesis of high-carbon sugar nucleoside antibiotics ENSG00000101751 ENSG00000122008 PMC8286267__F7 HBcrAg species, biogenesis, and application as biomarkers to monitor HBV gene expression and replication during natural resolution ENSG00000107338 PMC7566002__F9 A possible molecular network between RASSF1A, the Hippo pathway effector YAP1, AKT, FOXO3A, FOXM1, and ERA based on the findings in this paper and on the published literature ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000166851 PMC2080907__F8 Myc and Ca2+signaling events downstream of the pre-BCR/BCR ENSG00000100290 ENSG00000010810 ENSG00000186716 ENSG00000136997 ENSG00000197943 ENSG00000135605 ENSG00000010671 PMC9399422__F6 Identifying gene variants underlying the pathogenesis of diabetic retinopathy based on integrated genomic and transcriptomic analysis of clinical extreme phenotypes ENSG00000125879 ENSG00000111249 ENSG00000110237 ENSG00000173040 ENSG00000137727 ENSG00000169507 ENSG00000125538 ENSG00000187510 ENSG00000113971 ENSG00000076706 ENSG00000183160 ENSG00000196313 PMC11002909__F2 Antiviral role of ubiquitination in enterovirus infection ENSG00000132109 ENSG00000088888 ENSG00000112343 ENSG00000146054 ENSG00000121060 ENSG00000141569 PMC9162468__F2 Therapeutic strategies to induce mitophagy ENSG00000177169 ENSG00000158828 ENSG00000135093 PMC6463794__F6 Summary of the proposed inhibitory mechanisms exhibited by WG-391D in ovarian cancer ENSG00000135446 ENSG00000185591 ENSG00000205250 ENSG00000105810 ENSG00000101224 PMC7347881__F7 Reciprocal H3.3 gene editing identifies K27M and G34R mechanisms in pediatric glioma including NOTCH signaling ENSG00000178403 ENSG00000168214 ENSG00000136997 ENSG00000134853 ENSG00000273529 ENSG00000139352 PMC10382180__F3 Immunity by tryptophan microbial metabolites ENSG00000140505 ENSG00000106546 PMC5751200__F2 The BMP-2 signaling pathway plays an important role in the osteogenic differentiation of adipose-derived stem cells (ASCs) ENSG00000170365 PMC3058926__F4 Proof of Concept: A review on how network and systems biology approaches aid in the discovery of potent anticancer drug combinations ENSG00000104856 ENSG00000168564 ENSG00000005339 ENSG00000213658 ENSG00000138380 ENSG00000173039 PMC6433978__F2 Complement activation pathways and examples of complement-targeting therapeutics for IgAN ENSG00000039537 ENSG00000113600 ENSG00000116785 ENSG00000244414 ENSG00000134365 ENSG00000203710 ENSG00000292002 ENSG00000244731 ENSG00000166278 ENSG00000292003 ENSG00000236625 PMC4795442__F1 Pathogenesis of anti-neutrophil cytoplasmic antibody-associated vasculitis ENSG00000231021 ENSG00000005381 PMC8941137__F10 Beta-cell fitness comparison in Beta-cell replenishment under stress ENSG00000073111 PMC7998946__F1 Schematic comparison of metabolic pathways between a nontransformed cell and a cancer cell ENSG00000159399 PMC7139113__F1 Network for the genes included in mitochondrial functioning processes ENSG00000181220 ENSG00000106459 ENSG00000054523 PMC5366901__F4 Stepwise analysis of MIR9 loci identifies miR-9-5p to be involved in Oestrogen regulated pathways in breast cancer patients ENSG00000082175 ENSG00000129514 PMC3995778__F4 Overrepresentation of Glutamate Signaling in Alzheimer's Disease: Network-Based Pathway Enrichment Using Meta-Analysis of Genome-Wide Association Studies ENSG00000161681 ENSG00000181804 ENSG00000033800 ENSG00000162105 ENSG00000120251 PMC3995778__F5 Overrepresentation of Glutamate Signaling in Alzheimer's Disease: Network-Based Pathway Enrichment Using Meta-Analysis of Genome-Wide Association Studies ENSG00000144935 ENSG00000148798 ENSG00000115419 PMC9295998__F1 Multi-scale model construction ENSG00000211445 ENSG00000143196 ENSG00000176153 ENSG00000095002 PMC6562738__F5 RAC1 signaling in tumor cells: RAC1 signaling in tumors cells and the involvement of the RAC1 protein in tumorigenesis and drug-resistance as presented in the review ENSG00000159224 ENSG00000156299 ENSG00000291971 ENSG00000149269 ENSG00000198793 ENSG00000124126 ENSG00000171791 PMC5094987__F7 EZH2-mediated repression of GSK-3B and TP53 promotes Wnt/Beta-catenin signaling-dependent cell expansion in cervical carcinoma ENSG00000134982 ENSG00000168036 ENSG00000074266 ENSG00000178691 ENSG00000125084 PMC1940051__F2 TGFB signaling pathway ENSG00000019991 PMC4100138__F2 Autophagic cell death in lung tumor cells ENSG00000177169 ENSG00000083290 ENSG00000198793 PMC4237677__F3 Repeat associated non-ATG (RAN) translation: new starts in microsatellite expansion disorders ENSG00000180210 ENSG00000117525 ENSG00000132341 PMC4632830__F1 Heme biosynthesis pathway (in red) connects with glucose (in green) and glutamine (in blue) metabolic pathways ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000188690 PMC3634451__F2 FGF signalling cascade in Drosophila melanogaster ENSG00000159224 ENSG00000070831 PMC7862465__F2 Glycosylation changes in TGFB activation and SMAD-dependent pathway PMC4256494__F3 A, Cellular arginine metabolism and putative role of arginase in the development of renal fibrosis ENSG00000081181 ENSG00000100033 PMC4063399__F2 Resistance to vemurafenib ENSG00000019991 ENSG00000157764 PMC4611759__F1 Type I IFN gene expression ENSG00000183735 ENSG00000172936 ENSG00000184216 ENSG00000164342 PMC4611759__F2 Cellular response to IFNs ENSG00000105397 ENSG00000115415 ENSG00000160710 PMC4349729__F2 Simplified view of insulin/IGF1 signaling ENSG00000171105 ENSG00000198793 PMC4050971__F3 Ingenuity Pathway Analyses: Pathway analyses were from the commercially available Ingenuity Pathway Analysis software ENSG00000132671 ENSG00000072315 ENSG00000159882 ENSG00000162772 ENSG00000276561 PMC4084493__F2 Non-homologous end joining: emerging themes and unanswered questions ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000138346 ENSG00000039650 ENSG00000051180 ENSG00000138385 ENSG00000139618 PMC4050971__F4 Ingenuity Pathway Analyses: Details are as in ENSG00000105048 ENSG00000125734 ENSG00000114993 ENSG00000040633 ENSG00000113369 ENSG00000163914 ENSG00000158796 ENSG00000065548 ENSG00000164970 ENSG00000105767 ENSG00000162706 ENSG00000006042 PMC4720263__F4 Signaling crosstalk between the TGF-Beta-activated Smad pathway and the Wnt- and Notch-activated signaling pathways during EMT ENSG00000138795 ENSG00000168036 PMC8030716__F1 Entry of the virus leads to activation of the innate immune system which comprises of macrophages and dendritic cells ENSG00000134982 ENSG00000172936 PMC2721684__F1 Signaling pathways triggered by TLR3, TLR4 and TLR1–TLR2 ENSG00000183735 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC4812151__F2 Signaling pathway and biological function of Rap2B, a Ras family small guanosine 5′-triphosphate-binding protein ENSG00000159224 ENSG00000181467 ENSG00000154310 PMC5362762__F5 Exploration of small RNA-seq data for small non-coding RNAs in Human Colorectal Cancer ENSG00000142192 PMC11610194__F7 Regulatory networks of critical pattern pathways ENSG00000112576 ENSG00000070193 ENSG00000137713 ENSG00000157404 ENSG00000065675 ENSG00000291603 ENSG00000169862 ENSG00000169047 ENSG00000169884 ENSG00000168036 ENSG00000171791 ENSG00000145386 ENSG00000112715 ENSG00000121879 ENSG00000138356 ENSG00000140534 ENSG00000175130 ENSG00000213658 ENSG00000167941 ENSG00000056558 ENSG00000169429 ENSG00000002549 ENSG00000124181 ENSG00000112486 ENSG00000198286 ENSG00000104365 ENSG00000138795 ENSG00000173039 ENSG00000106483 ENSG00000175505 ENSG00000176153 ENSG00000129007 ENSG00000145604 ENSG00000094804 ENSG00000117020 ENSG00000170962 ENSG00000120899 ENSG00000118503 ENSG00000196218 ENSG00000104290 ENSG00000006747 ENSG00000060566 ENSG00000128965 PMC2693146__F8 Model depicting the dual role of cGKI in BMP signalling pathway cGKI regulates BMP signalling through (light blue) modulation of BMP receptors at the cell surface and enhancement of R-Smad phosphorylation and thus Smad activation ENSG00000125968 PMC8764205__F8 Estrogen receptor alpha and NFATc1 bind to a bone mineral density-associated SNP to repress WNT5B in osteoblasts ENSG00000004975 ENSG00000169071 ENSG00000070831 ENSG00000185483 ENSG00000168036 ENSG00000111186 ENSG00000161202 ENSG00000169375 ENSG00000131196 PMC6770048__F1 Proposed biosynthetic pathway leading to multiple terpenoids in I ENSG00000110921 ENSG00000197429 PMC7061741__F4 Schematic diagram shows the proposed mechanism by which the Hippo pathway regulates cervical cancer ENSG00000109321 ENSG00000163235 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC8533819__F3 Involvement of Kynurenine Pathway in Hepatocellular Carcinoma ENSG00000049768 ENSG00000168610 ENSG00000106546 PMC7061741__F5 Schematic diagram showing the proposed mechanism by which the Hippo signaling pathway regulates ovarian cancer ENSG00000066468 ENSG00000126016 ENSG00000160867 ENSG00000109321 ENSG00000198670 ENSG00000077782 ENSG00000146648 ENSG00000131023 PMC7061741__F6 Schematic diagram showing the proposed mechanism by which the Hippo signaling pathway regulates endometrial cancer ENSG00000033327 ENSG00000105699 ENSG00000138798 ENSG00000170558 ENSG00000198670 ENSG00000150457 ENSG00000247746 ENSG00000131023 PMC2719108__F2 Schematic representation of the renin angiotensin system ENSG00000175054 ENSG00000112977 ENSG00000130234 ENSG00000143839 PMC7061741__F7 Schematic diagram showing putative targets and small molecules specific to the Hippo pathway ENSG00000126016 ENSG00000150457 ENSG00000131023 PMC4086823__F3 Stochasticity of Intranuclear Biochemical Reaction Processes Controls the Final Decision of Cell Fate Associated with DNA Damage ENSG00000132906 ENSG00000164305 PMC4086823__F1 Stochasticity of Intranuclear Biochemical Reaction Processes Controls the Final Decision of Cell Fate Associated with DNA Damage ENSG00000149311 ENSG00000132906 ENSG00000164305 PMC4715999__F2 Microenvironment interactions and B-cell receptor signaling in Chronic Lymphocytic Leukemia: implications for disease pathogenesis and treatment ENSG00000177455 ENSG00000095585 ENSG00000105369 ENSG00000110448 ENSG00000007312 ENSG00000197943 ENSG00000277943 ENSG00000010671 PMC7368967__F10 Mechanistic target of rapamycin pathway downregulates bone morphogenetic protein signaling to promote oligodendrocyte differentiation ENSG00000170365 ENSG00000198793 ENSG00000196591 ENSG00000204217 PMC7061741__F2 Hippo pathway in mammals ENSG00000170365 ENSG00000197905 ENSG00000007866 ENSG00000131023 ENSG00000074219 ENSG00000084774 PMC12038455__F1 Implication of miR-21-5p and miR-214-5p in regulation of signal transducer and activator of transcription 3 signaling pathway ENSG00000178860 ENSG00000168610 PMC5864227__F1 Mutp53 accumulation in tumours is sustained by mechanical inputs through a mevalonate-RhoA-HDAC axis ENSG00000094631 PMC7508753__F2 Contribution of the embryo, fetus, and trophoblasts to the programming of immune adaptations during pregnancy ENSG00000081041 ENSG00000107562 ENSG00000276051 ENSG00000163734 ENSG00000124875 PMC12185286__F2 Mechanism of BMSCs transplantation on neural plasticity ENSG00000242689 PMC2785342__F8 A proposed model for HA-CD44-mediated PKCE activation and Nanog signaling in the regulation of miRNA-21 production, oncogenesis, and chemoresistance in breast tumor cells ENSG00000026508 ENSG00000113360 PMC3219211__F1 Small-molecule inhibitors in the ubiquitin–proteasome system (UPS) ENSG00000159593 ENSG00000167986 ENSG00000101557 PMC10784739__F7 TIFA regulating the inflammatory and osteoclast differentiation in the RAW264 ENSG00000162711 ENSG00000100985 ENSG00000131196 PMC5671979__F6 miRNA-mRNA network ENSG00000109113 ENSG00000134569 ENSG00000123572 ENSG00000138829 ENSG00000137845 ENSG00000004455 ENSG00000005893 ENSG00000090060 ENSG00000170027 ENSG00000152520 ENSG00000179151 ENSG00000162849 ENSG00000145777 ENSG00000139722 ENSG00000116001 ENSG00000174567 ENSG00000094804 ENSG00000163539 ENSG00000288210 ENSG00000069018 ENSG00000243709 ENSG00000060656 ENSG00000137992 ENSG00000151967 ENSG00000198846 ENSG00000127616 ENSG00000152556 ENSG00000064042 ENSG00000131725 ENSG00000196323 ENSG00000056586 ENSG00000124313 ENSG00000181826 ENSG00000109606 ENSG00000095015 ENSG00000172572 ENSG00000177468 ENSG00000118454 ENSG00000115295 ENSG00000081087 ENSG00000144868 ENSG00000185774 ENSG00000156639 ENSG00000197063 ENSG00000288293 ENSG00000070444 ENSG00000162624 ENSG00000140553 ENSG00000141503 ENSG00000111875 ENSG00000139372 ENSG00000168310 ENSG00000108256 ENSG00000135124 ENSG00000005469 ENSG00000177169 ENSG00000288283 ENSG00000160741 ENSG00000065135 ENSG00000121297 ENSG00000123360 ENSG00000162545 ENSG00000102974 PMC12055541__F4 Inflammatory Mechanisms Following SCI: In the acute injury phase: SCI directly causes vascular damage or severing, increasing the permeability of blood vessels ENSG00000169245 ENSG00000108691 ENSG00000081041 PMC12055541__F5 Molecular Mechanisms of Hydrogel in Improving the Microenvironment of SCI ENSG00000162711 ENSG00000181019 ENSG00000167468 ENSG00000172936 ENSG00000136869 ENSG00000118520 ENSG00000168610 ENSG00000079999 PMC9683337__F2 Receptor activator of nuclear factorKB ligand-mediated osteoclastogenesis signaling pathway and related therapeutic natural compounds ENSG00000110711 ENSG00000170909 ENSG00000175104 ENSG00000131196 ENSG00000079999 ENSG00000143387 PMC4406847__F4 ROS are important contributor to renal injury and inflammation ENSG00000162711 ENSG00000125538 ENSG00000265972 PMC5962651__F2 Schematic presentation of autophagy pathway and core autophagy-related proteins targeted by various miRNAs ENSG00000177169 ENSG00000110497 ENSG00000152348 ENSG00000198382 ENSG00000083290 ENSG00000126775 ENSG00000157954 ENSG00000057663 ENSG00000005893 ENSG00000144848 ENSG00000070540 ENSG00000079950 ENSG00000145782 PMC4309185__F2 Imd pathway in the fruit fly and the TNF pathway in the mouse ENSG00000102871 ENSG00000127191 PMC6726749__F10 Based on our findings, there are several crucial paths, including PI3/AKT/mTOR as well as HIF-1A activation (in hypoxia) and inhibition (in normoxia) ENSG00000124102 ENSG00000198793 ENSG00000124440 PMC4309185__F3 The Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway in the fruit fly and the mouse ENSG00000168610 PMC5640164__F2 Metabolic regulation of the immune humoral response ENSG00000177455 ENSG00000002330 ENSG00000186716 ENSG00000145321 ENSG00000103522 PMC4309185__F1 Toll pathway in the fruit fly and the Toll-like receptor (TLR) 4 pathway in the mouse ENSG00000170458 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC3913901__F2 cIAP1/2 regulation of TNFAlpha-induced canonical NFKB pathway activation and suppression of default death pathways ENSG00000102871 ENSG00000173039 ENSG00000168040 ENSG00000112186 ENSG00000168404 ENSG00000127191 ENSG00000064012 PMC3913901__F3 cIAP1/2 regulation of TWEAK-induced non-canonical NFKB pathway activation ENSG00000104856 ENSG00000131323 ENSG00000127191 PMC11784353__F10 Schematic diagrams illustrate how EIAV negatively regulates RLR pathway activation by degrading MAVS ENSG00000183735 ENSG00000088888 ENSG00000198742 PMC9284893__F7 RNA-seq reveals co-dysregulated circular RNAs in the adenomyosis eutopic endometrium and endometrial–myometrial interface ENSG00000280962 ENSG00000160551 ENSG00000120875 ENSG00000095015 ENSG00000168067 ENSG00000197442 ENSG00000155903 ENSG00000169032 ENSG00000099942 ENSG00000100485 ENSG00000102678 ENSG00000173327 ENSG00000008735 ENSG00000075461 ENSG00000077782 ENSG00000011485 ENSG00000109756 ENSG00000136068 ENSG00000142408 ENSG00000087095 ENSG00000104365 ENSG00000101109 ENSG00000117020 ENSG00000177189 ENSG00000167535 ENSG00000134853 ENSG00000140285 ENSG00000175104 PMC9284893__F8 RNA-seq reveals co-dysregulated circular RNAs in the adenomyosis eutopic endometrium and endometrial–myometrial interface ENSG00000087095 ENSG00000070831 ENSG00000170458 ENSG00000130522 ENSG00000138798 ENSG00000172936 ENSG00000130159 ENSG00000101224 ENSG00000175104 ENSG00000127191 ENSG00000081189 ENSG00000026103 PMC11665378__F5 Schematic view of the relationship between ncRNAs and the LC cell progression, invasion, and migration via the PI3K signaling pathway ENSG00000181019 ENSG00000146648 PMC11665378__F6 Non-coding RNAs and regulation of the PI3K signaling pathway in lung cancer: Recent insights and potential clinical applications ENSG00000170558 ENSG00000169047 ENSG00000146648 PMC5372827__F6 Strategies of enhancement of folate level in plants ENSG00000228716 ENSG00000095059 ENSG00000136877 ENSG00000137563 PMC11665378__F3 This schematic illustrates the downstream pathways influenced by AKT activation ENSG00000159224 ENSG00000002330 ENSG00000198793 PMC9382085__F8 Chang qing formula ameliorates colitis-associated colorectal cancer via suppressing IL-17/NFKB/STAT3 pathway in mice as revealed by network pharmacology study ENSG00000100985 ENSG00000168610 PMC11665378__F4 Schematic view of the relationship between ncRNAs and LC cell proliferation and apoptosis via the PI3K signaling pathway ENSG00000148400 ENSG00000135446 ENSG00000104967 ENSG00000105810 ENSG00000165819 PMC8072393__F2 Autophagic Organelles in DNA Damage Response ENSG00000198382 ENSG00000128272 ENSG00000126775 ENSG00000144895 ENSG00000100219 ENSG00000145782 ENSG00000057663 PMC11665378__F1 Non-coding RNAs and regulation of the PI3K signaling pathway in lung cancer: Recent insights and potential clinical applications ENSG00000198793 ENSG00000164327 ENSG00000167965 ENSG00000171608 PMC9339672__F1 Macrophage Polarization, Metabolic Reprogramming, and Inflammatory Effects in Ischemic Heart Disease ENSG00000125245 PMC8035741__F5 Graphical representation of the potential apoptotic pathway induced by the Human-RPSA siRNA in late (DLD-1) stage colorectal cancer cell ENSG00000188486 ENSG00000149311 ENSG00000168036 ENSG00000113734 PMC6421413__F8 Protein associations and potential functions of SHARPIN in human megakaryocytes and platelets ENSG00000173039 ENSG00000083799 ENSG00000154124 PMC7193283__F5 Mechanism of RES on improving NAFLD ENSG00000166819 ENSG00000135218 ENSG00000134013 ENSG00000187288 ENSG00000136869 ENSG00000096717 ENSG00000168610 ENSG00000026103 PMC7193283__F3 Mechanism of TSG on improving NAFLD ENSG00000138075 ENSG00000042832 ENSG00000167910 ENSG00000130649 ENSG00000026103 PMC8374068__F3 Critical Review of the Evidence That Metformin Is a Putative Anti-Aging Drug That Enhances Healthspan and Extends Lifespan ENSG00000169047 ENSG00000198793 PMC7193283__F4 Mechanism of emodin on improving NAFLD ENSG00000128272 ENSG00000042832 ENSG00000144895 ENSG00000198793 ENSG00000136869 PMC9409738__F5 Comprehensive Review on the Anti-Cancer Effects of Oleuropein ENSG00000198793 ENSG00000112561 ENSG00000169710 ENSG00000146648 PMC2928307__F1 Plastids play a central role in the generation of wounding and herbivory induced signals ENSG00000026103 PMC11544107__F5 Aripiprazole-target-disease-pathway network and molecular docking results of aripiprazole with core targets ENSG00000128310 ENSG00000175003 ENSG00000103222 ENSG00000087085 ENSG00000118777 ENSG00000010671 ENSG00000149295 ENSG00000163631 ENSG00000168830 ENSG00000276825 ENSG00000112038 ENSG00000133019 ENSG00000127663 ENSG00000184845 ENSG00000113749 ENSG00000196639 ENSG00000082556 ENSG00000077782 ENSG00000276996 ENSG00000179546 ENSG00000182578 ENSG00000138622 ENSG00000170214 ENSG00000158748 ENSG00000116329 ENSG00000164082 ENSG00000075073 ENSG00000274286 ENSG00000102468 ENSG00000043591 ENSG00000169676 ENSG00000010810 ENSG00000148680 ENSG00000180616 ENSG00000166224 PMC8985313__F8 Breast cancer metastasis to brain results in recruitment and activation of microglia through annexin-A1/formyl peptide receptor signaling ENSG00000115415 ENSG00000171049 ENSG00000168610 ENSG00000171051 PMC11544107__F4 Distribution of key targets in the two main pathways ENSG00000159224 ENSG00000148926 ENSG00000214285 ENSG00000174429 ENSG00000115718 ENSG00000171388 ENSG00000161610 ENSG00000115138 ENSG00000198670 ENSG00000134548 ENSG00000152266 ENSG00000113889 ENSG00000112964 ENSG00000100448 ENSG00000179091 ENSG00000138039 ENSG00000248329 ENSG00000166573 ENSG00000183979 ENSG00000007908 ENSG00000010310 ENSG00000274473 ENSG00000183395 ENSG00000139574 ENSG00000096395 ENSG00000069482 ENSG00000291972 ENSG00000004948 ENSG00000102239 ENSG00000151617 ENSG00000116096 PMC7328045__F1 Proposed inhibition of SARS-CoV-2 entry/replication by intervention at the NPC1 pathway ENSG00000130234 ENSG00000184012 ENSG00000141458 PMC8841848__F3 Evasion of Host Antiviral Innate Immunity by Paramyxovirus Accessory Proteins ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000121060 ENSG00000142166 PMC7759481__F1 Induction of IFNs and the antiviral state they exhibit in bat (P ENSG00000183735 ENSG00000088888 ENSG00000187608 ENSG00000105397 ENSG00000089127 ENSG00000115415 ENSG00000177606 ENSG00000172936 ENSG00000131323 ENSG00000135828 ENSG00000276561 PMC2677440__F7 Rhinovirus-Induced Major Airway Mucin Production Involves a Novel TLR3-EGFR–Dependent Pathway ENSG00000291363 ENSG00000109321 ENSG00000163235 ENSG00000146648 ENSG00000164342 PMC11743330__F2 MiR‐30a‐5p inhibiting the Wnt/B‐catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC4796280__F2 Store-dependent and -independent Ca2+ entry pathways in smooth muscle ENSG00000175938 ENSG00000283887 ENSG00000167323 ENSG00000293604 ENSG00000198793 PMC6826537__F1 Pathways controlling the epithelial-mesenchymal transition (EMT) program in prostate cancer (PC) ENSG00000170558 ENSG00000069812 ENSG00000168036 ENSG00000114315 ENSG00000078098 PMC3900298__F5 New immunological approaches in treating and diagnosing CNS diseases ENSG00000106571 ENSG00000164690 ENSG00000196689 PMC4747375__F7 Amphiregulin enhances intercellular adhesion molecule-1 expression and promotes tumor metastasis in human osteosarcoma ENSG00000109321 ENSG00000146648 PMC5532623__F2 MET regulated signaling pathways implicated in the hallmarks of cancer ENSG00000019991 ENSG00000291971 ENSG00000168610 PMC3647962__F13 TNFA signaling pathways to IKK activation ENSG00000102871 ENSG00000127191 PMC8706409__F10 Single-Cell and Bulk RNASeq Profiling of COVID-19 Patients Reveal Immune and Inflammatory Mechanisms of Infection-Induced Organ Damage ENSG00000104365 ENSG00000285109 ENSG00000168610 PMC2949127__F3 HMGB1 signaling events mediated by RAGE and TLR2/4 and therapeutic strategies for cerebral ischemia ENSG00000070831 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC9410782__F1 Advances in Research on the Molecular Function and Specific Role of Circular RNA in Cardiovascular Diseases ENSG00000117020 ENSG00000281324 ENSG00000150907 ENSG00000158828 ENSG00000198576 ENSG00000172936 ENSG00000096717 PMC6734673__F2 Epidermal growth factor receptor Pathway and its two pathways: Ras/Raf/Mitogen-activated protein kinases or PI3K/AKT ENSG00000198793 ENSG00000146648 PMC5698505__F3 mTOR signaling PMC6559821__F3 Main signaling involved in non-canonical pathways regulating HIF-1/2 ENSG00000134086 ENSG00000198793 PMC6147171__F3 Mechanisms contributing to the repression of hepatic gluconeogenesis by Wnt signaling activation ENSG00000124253 ENSG00000160741 PMC9359802__F4 Transcriptional response to VZV infection is modulated by RNA polymerase III in lung epithelial cell lines ENSG00000088888 ENSG00000135828 ENSG00000164342 PMC5628821__F6 Design and validation of a 90K SNP genotyping assay for the water buffalo (Bubalus bubalis) ENSG00000160789 ENSG00000151376 ENSG00000100445 ENSG00000179915 ENSG00000278619 ENSG00000214046 ENSG00000181045 ENSG00000159885 ENSG00000172244 ENSG00000172733 ENSG00000103061 ENSG00000083828 ENSG00000196505 ENSG00000153214 ENSG00000146083 ENSG00000146147 ENSG00000101452 ENSG00000123353 ENSG00000090530 ENSG00000168701 ENSG00000140464 ENSG00000019505 PMC6147171__F1 A) A simplified schematic of the Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC9332329__F2 Interactions between phages and immune system components are varied and complex ENSG00000174125 ENSG00000117525 ENSG00000239732 ENSG00000163568 ENSG00000172936 ENSG00000164342 PMC6135464__F5 Pathway visualisation ENSG00000090402 PMC3190874__F2 FcERI signaling pathway is negatively regulated by a number of cell surface and intracellular proteins that act at various points in the FcERI signaling network ENSG00000213658 ENSG00000010810 ENSG00000136869 ENSG00000010671 PMC9263675__F4 Update on the pathogenesis of vitiligo ENSG00000169245 ENSG00000186810 ENSG00000111537 ENSG00000115415 ENSG00000138755 ENSG00000105639 PMC3190874__F1 Immunoglobulin E Receptor Signaling and Asthma ENSG00000213658 ENSG00000010810 ENSG00000198793 ENSG00000010671 PMC4884112__F8 Proposed crosstalk between EGFR signaling pathway and Hippo pathway in the diabetic kidney ENSG00000109321 ENSG00000113070 ENSG00000146648 ENSG00000131023 PMC9949365__F1 Orthogonal Functional Genomic and Proteomic Analyses Nominate AKT Activation as an Actionable Consequence of Selinexor Treatment ENSG00000140992 ENSG00000117020 ENSG00000119487 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000168040 ENSG00000166851 ENSG00000174611 PMC9015684__F1 Astroglial Serotonin Receptors as the Central Target of Classic Antidepressants ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC8458546__F3 Proliferative diabetic retinopathy transcriptomes reveal angiogenesis, anti-angiogenic therapy escape mechanisms, fibrosis and lymphatic involvement ENSG00000148400 ENSG00000152402 ENSG00000112715 ENSG00000164305 ENSG00000147145 ENSG00000143125 ENSG00000108556 ENSG00000125249 ENSG00000164742 ENSG00000213949 ENSG00000188257 ENSG00000100302 ENSG00000144118 ENSG00000197943 ENSG00000163072 ENSG00000100985 ENSG00000154188 ENSG00000142546 ENSG00000064012 PMC9479335__F5 Case report of the sustained and rapid response of bevacizumab in a TP53-positive breast cancer and liver metastatic patient through personalized medicine ENSG00000198793 PMC7086291__F2 Leukocyte extravasation signaling ENSG00000169896 ENSG00000166086 ENSG00000150093 ENSG00000154721 ENSG00000100985 PMC7086291__F3 Tec kinase signaling ENSG00000291971 ENSG00000135605 PMC7086291__F4 Osteoarthritis signaling ENSG00000139219 ENSG00000170365 ENSG00000163435 ENSG00000291837 ENSG00000168036 ENSG00000136869 ENSG00000002745 ENSG00000007171 ENSG00000158859 PMC6618585__F2 Tumorigenic mechanisms of Fusobacterium nucleatum in colorectal cancer ENSG00000023445 ENSG00000181847 ENSG00000172936 ENSG00000136869 PMC7139528__F6 Nervous system interaction effects of the KEGG enrichment pathway terms and putative target proteins identified in A ENSG00000142192 ENSG00000130643 ENSG00000087085 ENSG00000164082 ENSG00000171791 ENSG00000169032 ENSG00000182621 ENSG00000107175 ENSG00000164305 ENSG00000087460 ENSG00000274542 ENSG00000149295 ENSG00000108839 ENSG00000117020 ENSG00000184845 ENSG00000144935 ENSG00000169676 ENSG00000243708 ENSG00000010810 ENSG00000095303 ENSG00000069966 PMC8226978__F1 Dietary Phytochemicals in Zinc Homeostasis: A Strategy for Prostate Cancer Management ENSG00000002330 ENSG00000145321 ENSG00000171791 ENSG00000168610 PMC6892284__F1 Number of studies suggest that an increase in microbial BSH activity results in a reduction in stimulation of intestinal FXR ENSG00000138075 ENSG00000167910 ENSG00000143921 PMC9200584__F3 Integrating Network Pharmacology and Experimental Validation to Explore the Key Mechanism of Gubitong Recipe in the Treatment of Osteoarthritis ENSG00000169248 ENSG00000162711 ENSG00000138798 ENSG00000171791 ENSG00000112715 ENSG00000164305 ENSG00000149968 ENSG00000128052 ENSG00000136997 ENSG00000169429 ENSG00000132906 ENSG00000104365 ENSG00000081041 ENSG00000100906 ENSG00000173039 ENSG00000007908 ENSG00000213341 ENSG00000073756 ENSG00000007171 ENSG00000169245 ENSG00000108691 ENSG00000111537 ENSG00000118785 ENSG00000177606 ENSG00000291748 ENSG00000100985 ENSG00000146648 PMC5394985__F1 Interluekin-17A (IL17A) ENSG00000108691 ENSG00000163739 ENSG00000169429 ENSG00000168610 ENSG00000069667 PMC11252768__F8 Working summary of the study ENSG00000113161 ENSG00000128602 PMC6496424__F1 Multiple mechanisms involved in the protective roles of NLRP6 in intestinal epithelial cells ENSG00000150782 ENSG00000174885 ENSG00000172936 ENSG00000293532 PMC7186417__F5 Pro- and anti-fibrogenic effects of LPS on activated HSCs ENSG00000136869 ENSG00000112115 ENSG00000168610 PMC4873813__F2 Prevention of antipsychotic-induced hyperglycaemia by vitamin D: a data mining prediction followed by experimental exploration of the molecular mechanism ENSG00000171105 ENSG00000135218 ENSG00000169047 ENSG00000198793 ENSG00000173599 ENSG00000168610 PMC8069635__F3 Immune response pathway of SARS-CoV-2 ENSG00000130234 ENSG00000184012 PMC2099483__F1 Circadian oscillation in leptin signaling pathway in mouse brown fat ENSG00000168610 PMC8342764__F3 Cerebral Autoregulation in Subarachnoid Hemorrhage ENSG00000001626 PMC9441491__F7 Long non-coding RNAs play an important regulatory role in tumorigenesis and tumor progression through aerobic glycolysis ENSG00000198793 ENSG00000169047 ENSG00000077782 ENSG00000168610 ENSG00000159399 PMC5821995__F3 Macrophage polarization in type 2 diabetes ENSG00000149311 ENSG00000125538 ENSG00000168036 ENSG00000118971 PMC8115150__F8 Schematic model describing the protective effect of Mzb1 in AMI. Injury of cardiomyocytes led to apoptosis and mitochondrial dysfunction, ROS release, and increased inflammation PMC1526596__F1 P38 mitogen-activated protein kinase (MAPK) signaling cascade in T cells ENSG00000291603 ENSG00000099860 ENSG00000116717 PMC6770807__F6 Proposed action mechanism of 6SL ENSG00000132646 ENSG00000105810 PMC5893867__F1 Fasciola hepatica modulates macrophage activation ENSG00000162711 ENSG00000170458 ENSG00000136869 ENSG00000164342 ENSG00000105227 PMC6561619__F10 Model of the molecular mechanisms involved in LRRK2 gene silencing in proliferation, migration, and apoptosis in TC cells ENSG00000135446 PMC8863805__F1 An enhanced triple fluorescence flow-cytometry-based assay shows differential activation of the Notch signaling pathway by human papillomavirus E6 proteins ENSG00000283780 ENSG00000114315 ENSG00000137845 PMC3600829__F4 Functional analysis of the gene expression networks, performed using Ingenuity Pathway Analysis (IPA) ENSG00000177575 ENSG00000148346 ENSG00000145365 ENSG00000203710 ENSG00000229314 ENSG00000101695 ENSG00000100385 ENSG00000122025 ENSG00000177272 ENSG00000111537 ENSG00000069869 ENSG00000173757 ENSG00000106070 ENSG00000090376 ENSG00000268500 PMC3350083__F1 Overlap in FcERI, FcGRIII, and FcGRIIB signaling ENSG00000105329 ENSG00000010810 PMC2936296__F2 RIG-I signalling pathway ENSG00000088888 ENSG00000178573 ENSG00000006451 ENSG00000111837 ENSG00000173039 ENSG00000145782 PMC7961611__F1 Transsulfuration pathway (TSP) and related pathways ENSG00000158104 PMC2652403__F1 Signalling through the phosphatidylinositol 3-kinase (PI3K) affects cell growth, apoptosis and cell cycle regulation ENSG00000002330 ENSG00000198793 ENSG00000168036 PMC7961611__F2 Hydrogen sulfide production pathways PMC6107379__F1 RAS/mitogen-activated protein kinase (MAPK) signaling pathway and associated developmental syndromes (indicated by dashed lines) ENSG00000157764 ENSG00000110395 ENSG00000115904 ENSG00000166068 ENSG00000108061 ENSG00000196712 ENSG00000062485 PMC4076960__F8 Muscle hypertrophy and atrophy ENSG00000019991 ENSG00000111046 ENSG00000111049 ENSG00000122180 ENSG00000198793 ENSG00000134363 ENSG00000143933 ENSG00000141564 ENSG00000124762 ENSG00000158022 ENSG00000129152 ENSG00000131196 ENSG00000140443 ENSG00000114739 PMC9152764__F1 High Intensity Interval Training: A Potential Method for Treating Sarcopenia ENSG00000167658 ENSG00000096717 PMC11940482__F5 Calcium signaling pathway with RMPs ENSG00000124102 ENSG00000182533 ENSG00000130528 ENSG00000156026 ENSG00000186716 ENSG00000112561 PMC6050811__F1 The cyclin D1–CDK4/6–RB pathway in breast cancer.The role of the cyclin D1–CDK4/6-RB pathway in breast cancer cells, including cross talk with other oncogenic signaling pathways ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000146648 PMC7594502__F2 Mitophagy pathways in health and disease ENSG00000215021 ENSG00000183735 ENSG00000123240 ENSG00000160703 ENSG00000069509 PMC6289780__F4 Representative terpenoid biosynthesis pathway with cognate heat maps for transcript levels of genes ENSG00000067064 ENSG00000152904 ENSG00000197429 ENSG00000148377 PMC9373848__F1 Autophagy in Adrenal Tumors ENSG00000110497 ENSG00000102189 ENSG00000145782 ENSG00000057663 PMC11814419__F6 Schematic for the mechanism by which PGAM1 functions to promote the malignant phenotypes of BC via the Wnt/Beta-Catenin signaling pathway ENSG00000134982 ENSG00000168036 PMC2923738__F4 Human erythrocyte metabolism modeled using detailed enzyme rate equations ENSG00000151657 ENSG00000154016 PMC9598206__F7 GPX4 Alleviates Diabetes Mellitus-Induced Erectile Dysfunction by Inhibiting Ferroptosis ENSG00000167468 ENSG00000111684 PMC3249418__F3 Migration of marginal zone precursor B cells regulated by type I interferon (IFN) and IL-17 PMC5054603__F3 Gene expression changes in neurotransmitter signaling pathways ENSG00000145864 ENSG00000171723 ENSG00000154001 ENSG00000050748 ENSG00000167083 ENSG00000176533 ENSG00000088256 ENSG00000174021 ENSG00000171791 ENSG00000242616 ENSG00000151834 ENSG00000276825 ENSG00000155980 ENSG00000120251 ENSG00000157542 ENSG00000162188 ENSG00000167414 ENSG00000011677 ENSG00000127928 ENSG00000114450 ENSG00000115993 ENSG00000172380 ENSG00000147434 ENSG00000078369 ENSG00000145863 ENSG00000127955 ENSG00000268089 ENSG00000105568 ENSG00000115896 ENSG00000137841 ENSG00000163285 ENSG00000182256 ENSG00000065135 ENSG00000164742 ENSG00000102287 ENSG00000117020 ENSG00000173805 ENSG00000174233 ENSG00000010810 ENSG00000094755 ENSG00000113327 ENSG00000127588 ENSG00000105723 ENSG00000069966 ENSG00000186469 PMC5877574__F2 The signaling pathways in response to DNA damage and key effectors that interact with ER signaling ENSG00000149311 ENSG00000175054 ENSG00000135446 PMC6826993__F2 After co-culture between adipocytes and breast cancer (BC) cells, high levels of miR-144 and miR-126 were released by exosomes by BC cells ENSG00000125398 ENSG00000291971 ENSG00000169047 ENSG00000198793 ENSG00000104918 ENSG00000152952 ENSG00000168610 PMC5054603__F4 Gene expression changes in the elements of postsynaptic signaling cascades ENSG00000167414 ENSG00000140992 ENSG00000127928 ENSG00000172380 ENSG00000167083 ENSG00000127955 ENSG00000042753 ENSG00000176533 ENSG00000174021 ENSG00000242616 ENSG00000137841 ENSG00000065135 ENSG00000100151 ENSG00000108556 ENSG00000176884 ENSG00000125675 ENSG00000166501 ENSG00000163873 ENSG00000186469 PMC8573439__F1 Mechanisms and pharmacological applications of ferroptosis: a narrative review ENSG00000168003 ENSG00000139514 ENSG00000167468 ENSG00000197429 ENSG00000111684 ENSG00000115107 ENSG00000057663 ENSG00000136381 ENSG00000079999 PMC11803289__F2 How S1P works ENSG00000170989 ENSG00000180739 ENSG00000213694 ENSG00000125910 ENSG00000267534 PMC7073561__F1 Lipid biosynthesis ENSG00000169710 ENSG00000148154 ENSG00000102172 PMC3075710__F3 Regulated fatty acid synthesis and metabolism during cell differentiation ENSG00000039537 ENSG00000042832 ENSG00000132646 ENSG00000197142 ENSG00000166278 ENSG00000143418 PMC6495170__F2 Ceramide metabolism ENSG00000139624 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000102172 ENSG00000143418 PMC9334647__F2 Caveolin-1 in Sepsis – A Mini-Review ENSG00000112715 PMC2670612__F2 Tumor resistance to EGFR-targeted therapies ENSG00000017797 ENSG00000146648 PMC5259950__F6 Canonical Rho signaling pathways were identified in a phosphoproteomics screen of HIV-1 signaling via CD4 and CCR5 ENSG00000038382 ENSG00000172380 ENSG00000175866 ENSG00000070831 ENSG00000170458 ENSG00000134982 ENSG00000138798 ENSG00000181104 ENSG00000102302 ENSG00000089159 PMC3199279__F2 Metabolic interactions between folates and vitamins B12, B6, and B2 ENSG00000228716 PMC7773902__F2 Summary of the different therapeutics applied in aGVHD treatment ENSG00000178860 ENSG00000134982 ENSG00000163599 PMC5841936__F2 Elotuzumab for the Treatment of Relapsed or Refractory Multiple Myeloma, with Special Reference to its Modes of Action and SLAMF7 Signaling ENSG00000158473 ENSG00000010810 ENSG00000166278 PMC5215107__F3 Genetic and Developmental Basis of Cardiovascular Malformations ENSG00000170365 ENSG00000136535 ENSG00000105329 PMC5841936__F3 Elotuzumab for the Treatment of Relapsed or Refractory Multiple Myeloma, with Special Reference to its Modes of Action and SLAMF7 Signaling ENSG00000111537 ENSG00000105656 ENSG00000166278 PMC6697739__F6 An illustration of the bidirectional interaction between Th17 and BEC ENSG00000111537 ENSG00000168610 ENSG00000115009 ENSG00000112486 ENSG00000106546 PMC7523953__F4 Comparative transcriptome analysis reveals candidate genes related to cadmium accumulation and tolerance in two almond mushroom (Agaricus brasiliensis) strains with contrasting cadmium tolerance ENSG00000109814 ENSG00000131473 PMC3900785__F1 The metabolic pathway of homocysteine PMC5578024__F8 Differentially expressed genes associated with the cell cycle were annotated by KEGG ENSG00000145604 ENSG00000108055 ENSG00000132646 ENSG00000115942 ENSG00000123374 ENSG00000205250 ENSG00000277273 ENSG00000276876 PMC10754983__F7 Current insight on the mechanisms of programmed cell death in sepsis-induced myocardial dysfunction ENSG00000177169 ENSG00000198793 PMC3868899__F8 Nicotine’s effect on immunity via the A4 nAChR signaling pathway in T cells ENSG00000169258 ENSG00000070831 PMC4197746__F2 mTOR controls metabolism ENSG00000177169 ENSG00000126775 ENSG00000167965 ENSG00000084774 PMC5503208__F2 Molecular mechanisms of dietary fat absorption within enterocytes ENSG00000087253 ENSG00000197142 ENSG00000285199 ENSG00000123983 ENSG00000026103 PMC4197746__F1 Upstream of mTOR: classical and non-classical inputs ENSG00000177169 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000106070 ENSG00000198793 ENSG00000169047 ENSG00000145979 ENSG00000164327 ENSG00000167965 PMC11251740__F1 Clinically relevant dysregulated pathways in GBM ENSG00000135446 ENSG00000198793 ENSG00000134853 ENSG00000105810 ENSG00000146648 ENSG00000196712 PMC7295046__F9 Schematic illustration showing the proposed mechanism by which FABP5 promotes LNM of CCa by regulating FA metabolism ENSG00000122691 ENSG00000169710 ENSG00000100985 ENSG00000150630 PMC4340667__F4 Targeting mitochondria metabolism for cancer therapy ENSG00000065911 ENSG00000100714 PMC5362638__F2 MyomiR interaction with Akt-mTORC1 signaling pathway ENSG00000169047 PMC3414811__F2 Two branches of the unfolded protein response ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000171791 ENSG00000127191 PMC3414811__F3 The mechanism of SLS ENSG00000144895 PMC8124393__F2 Long Non-Coding RNAs as Functional Codes for Oral Cancer: Translational Potential, Progress and Promises ENSG00000281324 ENSG00000162337 ENSG00000198793 ENSG00000168036 PMC7081367__F3 Disorders Caused by Genetic Mosaicism ENSG00000198793 ENSG00000196712 PMC9407616__F9 Transcriptome Analysis Identifies Key Metabolic Changes in the Brain of Takifugu rubripes in Response to Chronic Hypoxia ENSG00000275125 ENSG00000138029 ENSG00000078053 ENSG00000114268 ENSG00000189403 ENSG00000182621 ENSG00000173210 ENSG00000141934 PMC8946740__F10 Proposed model of ARF-IFNB pathway ENSG00000213928 ENSG00000115415 ENSG00000142166 PMC3478592__F1 Model depicts the development of conventional vs ENSG00000137265 ENSG00000113263 PMC4715152__F1 TRAF2 signal pathway networks ENSG00000102871 ENSG00000111321 ENSG00000131323 ENSG00000127191 PMC4715152__F3 WWOX/WOX1 and signaling networks ENSG00000019991 ENSG00000068001 ENSG00000178568 PMC7718394__F5 Simplified diagram illustrating altered innate signaling following BCG treatment of HU and HEU monocytes ENSG00000110944 ENSG00000081041 ENSG00000163739 ENSG00000108688 ENSG00000164400 ENSG00000172936 ENSG00000073756 ENSG00000142224 ENSG00000123610 PMC4695002__F6 STAT3 pathway regulates lung-derived brain metastasis initiating cell capacity through miR-21 activation ENSG00000197275 ENSG00000147862 ENSG00000114346 ENSG00000144642 ENSG00000136997 ENSG00000137203 ENSG00000185591 ENSG00000168610 ENSG00000095002 ENSG00000183580 ENSG00000062716 PMC4736761__F4 Changes in genes associated with epithelial-to-mesenchymal transition after radiation ENSG00000100234 ENSG00000123144 ENSG00000178951 ENSG00000119888 ENSG00000170558 ENSG00000169710 ENSG00000164327 ENSG00000148344 ENSG00000179588 ENSG00000158125 ENSG00000168283 ENSG00000011422 ENSG00000196549 ENSG00000038427 ENSG00000149968 ENSG00000164400 ENSG00000128342 ENSG00000283060 ENSG00000078098 ENSG00000130513 ENSG00000148346 ENSG00000184916 ENSG00000173546 ENSG00000170961 ENSG00000101255 ENSG00000163235 ENSG00000100985 ENSG00000175104 PMC5426651__F13 Mechanism of GnRH-(1–5) action in Ishikawa cells ENSG00000165370 ENSG00000138798 ENSG00000146648 PMC4736761__F3 Cellular processes common to all nine cancer stem cell- (CSC-) associated genes ENSG00000168283 ENSG00000148400 ENSG00000026508 ENSG00000146648 PMC7226484__F2 L-cysteine metabolism ENSG00000139531 ENSG00000116761 PMC4695002__F2 STAT3 pathway regulates lung-derived brain metastasis initiating cell capacity through miR-21 activation ENSG00000058085 ENSG00000291971 ENSG00000204463 ENSG00000162520 ENSG00000198793 ENSG00000288146 ENSG00000141564 ENSG00000168610 ENSG00000046604 ENSG00000187778 PMC1195384__F2 Folate pathway in Plasmodium falciparum and the proposed mode of action of the diaminopteridines, analogs of folate precursors ENSG00000228716 ENSG00000112977 ENSG00000095059 ENSG00000136877 PMC3943663__F1 Dendritic cells in progression and pathology of HIV infection ENSG00000132256 ENSG00000121966 PMC89003__F2 IFN signaling by the Jak-Stat pathway ENSG00000105397 ENSG00000115415 ENSG00000027697 PMC8616143__F1 Unfolded Protein Response as a Guardian of the Secretory Pathway ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC11311379__F9 Regulatory effects of novel-m0230-3p on cell TJs and adhesion via CSF1/CSF1R/Ras signaling pathway in yak SCs ENSG00000182578 ENSG00000184371 PMC5119498__F1 Factors Implicated in Insulin/Growth Factor-Induced Regulation of Mammalian or Mechanistic Target of Rapamycin (mTOR) Complex-1 (mTORC1) ENSG00000177169 ENSG00000198793 ENSG00000112561 ENSG00000167965 PMC5228376__F3 Cytokine-cytokine receptor interaction of secreted cytokines ENSG00000182578 ENSG00000019991 ENSG00000157404 ENSG00000275718 ENSG00000138798 ENSG00000183625 ENSG00000274736 ENSG00000112715 ENSG00000277943 ENSG00000122025 ENSG00000049130 ENSG00000128052 ENSG00000277236 ENSG00000108688 ENSG00000108700 ENSG00000181374 ENSG00000184371 ENSG00000006606 ENSG00000037280 ENSG00000275095 ENSG00000146648 ENSG00000106178 PMC6083487__F4 Cyclins and cell cycle regulation is the top pathway downregulated by citalopram treatment ENSG00000175054 ENSG00000150787 ENSG00000276876 PMC6463920__F6 Microgravity regulates cell proliferation and cell cycle via the CD117-Ras/cAMP-CREB pathway ENSG00000112576 ENSG00000128272 ENSG00000169032 ENSG00000118971 ENSG00000282899 ENSG00000158050 PMC5866782__F2 Free-fatty acid receptor-4 (FFA4) in human cancers and cancer cell lines ENSG00000170558 PMC3389589__F1 Finding a better drug for epilepsy: The mTOR pathway as an antiepileptogenic target ENSG00000198793 PMC3580761__F2 Regulation network of CYP3A4 phenotype expression adapted from Klein et al ENSG00000170608 ENSG00000164040 ENSG00000137491 ENSG00000127948 ENSG00000136689 PMC1857250__F2 Tregs and rethinking cancer immunotherapy ENSG00000163599 ENSG00000049768 PMC5064863__F5 Endocrine related Hippo Signaling Pathway ENSG00000104899 ENSG00000126016 ENSG00000110330 ENSG00000134982 ENSG00000109321 ENSG00000168036 ENSG00000150457 ENSG00000081051 ENSG00000132849 ENSG00000131023 ENSG00000072415 ENSG00000140807 ENSG00000089685 ENSG00000136997 ENSG00000168646 ENSG00000169435 ENSG00000125968 PMC4855716__F6 miRNA-gene network in the steroid hormone biosynthesis pathway and regulatory network in early sex differentiation of Nile tilapia ENSG00000104899 ENSG00000137090 ENSG00000179142 PMC9443660__F5A Targeting spike protein-induced TLR/NET axis by COVID-19 therapeutic NRICM102 ameliorates pulmonary embolism and fibrosis ENSG00000105664 ENSG00000130234 ENSG00000111837 ENSG00000160710 ENSG00000166278 PMC4000931__F3 Summary of the miRNAs and the VEGF pathway involved in HSCs ENSG00000132906 ENSG00000166068 PMC12084487__F2 Specific signaling pathways mediated programmed cell death in tumor microenvironment and target therapies ENSG00000124256 ENSG00000137275 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC12084487__F3 In the mTOR signaling pathway, PI3 K/AKT/mTOR axis can induce the occurrence of apoptosis ENSG00000101407 ENSG00000177169 ENSG00000002330 ENSG00000151012 ENSG00000137275 ENSG00000167468 ENSG00000155792 ENSG00000167965 PMC7383642__F1 Reported coagulation pathway variations in African Americans ENSG00000160752 ENSG00000110799 ENSG00000122194 PMC6100747__F3 Notch signaling pathway ENSG00000127445 ENSG00000128917 ENSG00000138798 ENSG00000136997 ENSG00000184916 ENSG00000137845 ENSG00000181026 ENSG00000090932 PMC6100747__F1 Ischemic stroke initiates cell death mechanisms in brain cells following an acute depletion of blood flow, resulting in the formation of an infarct core ENSG00000125538 PMC7230881__F7 Summary of the cellular response to oxidative stress in CC4348 (A) and the gpx5 mutant (B) PMC10758606__F1 NFKB signaling system in the generation of B-cell subsets: from germinal center B cells to memory B cells and plasma cells ENSG00000104856 ENSG00000173039 PMC12056177__F7 Schematic description of kinase signaling pathways in Alzheimer’s disease ENSG00000149311 ENSG00000142192 ENSG00000065361 ENSG00000010810 ENSG00000198793 ENSG00000146216 ENSG00000167658 ENSG00000101224 ENSG00000096717 ENSG00000137845 ENSG00000168610 PMC12056177__F8 Schematic description of kinase signaling pathways in Parkinson’s disease ENSG00000143799 ENSG00000158828 ENSG00000106305 PMC6040236__F7 Schematic for alternative complement pathway activity in fHm/m/fP−/− mice ENSG00000197713 PMC12056177__F9 Schematic description of kinase signaling pathways in Huntington’s disease ENSG00000198793 ENSG00000197386 PMC12056177__F6 MAP3K-MAP2K-MAPK signaling pathway ENSG00000173327 PMC7037688__F2 NF-E2 p45-related factor 2 (NRF2) transcription pathway and evaluation of potential biomarkers in Friedreich’s ataxia ENSG00000167468 ENSG00000116701 PMC6100747__F5 Following stroke, the stability of NICD is increased by its interaction with Pin1, and the NICD-Pin1 complex then translocates to the nucleus ENSG00000127445 ENSG00000134086 ENSG00000181026 PMC4995965__F4 DVL phosphorylation by NEK2 affects Wnt signaling ENSG00000117650 PMC10380727__F2 Bioactive Compounds and Cardiac Fibrosis: Current Insight and Future Prospect ENSG00000039537 ENSG00000168036 ENSG00000137672 PMC6810715__F2 Clinical and Molecular Phenotyping in Scleromyxedema Pre- and Post-Treatment with Intravenous Immunoglobulin ENSG00000157933 ENSG00000070831 ENSG00000133937 ENSG00000105329 ENSG00000156574 ENSG00000171791 ENSG00000169032 ENSG00000135341 ENSG00000177426 ENSG00000170365 ENSG00000198742 ENSG00000102935 ENSG00000104899 ENSG00000137834 ENSG00000115297 ENSG00000183072 ENSG00000065559 ENSG00000180806 ENSG00000276561 ENSG00000160973 ENSG00000104814 ENSG00000177606 ENSG00000164093 ENSG00000175104 ENSG00000157450 PMC7991106__F1 Process of glycometabolism in ECs ENSG00000180210 ENSG00000150907 ENSG00000159399 PMC2897145__F7 Molecularly and temporally separable lineages comprise the hindbrain roof plate and contribute differentially to the choroid plexus ENSG00000213658 PMC7248369__F7 Integration of transcriptomic and metabolomic data ENSG00000292286 ENSG00000188822 ENSG00000060982 ENSG00000162882 ENSG00000147100 ENSG00000169710 ENSG00000164120 ENSG00000143375 ENSG00000211445 ENSG00000128050 ENSG00000164742 ENSG00000174358 ENSG00000291507 ENSG00000136997 ENSG00000171848 ENSG00000002549 ENSG00000139687 PMC7867633__F4 Spinal muscular atrophy: Broad disease spectrum and sex-specific phenotypes ENSG00000177169 ENSG00000101751 ENSG00000273772 ENSG00000166169 ENSG00000113494 PMC4301186__F1 Interplay between lifespan regulation and brain function ENSG00000198793 ENSG00000281518 ENSG00000096717 PMC3010981__F1 Aldose Reductase Inhibition Prevents Metaplasia of Airway Epithelial Cells ENSG00000291363 ENSG00000117983 PMC7867633__F1 Spinal muscular atrophy: Broad disease spectrum and sex-specific phenotypes ENSG00000101751 ENSG00000166169 ENSG00000106459 PMC6768965__F1 Manipulation of the interferon signaling pathway in myeloid cells ENSG00000111605 ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000131323 ENSG00000125347 PMC7867633__F3 Spinal muscular atrophy: Broad disease spectrum and sex-specific phenotypes ENSG00000101751 ENSG00000115904 ENSG00000185591 ENSG00000166169 ENSG00000146648 PMC7246472__F2 Activators and inhibitors of Wnt/Beta-catenin signaling pathway ENSG00000120149 ENSG00000120057 ENSG00000168036 ENSG00000189403 ENSG00000096717 PMC6959606__F4 Gene expression profiling of Trypanosoma cruzi in the presence of heme points to glycosomal metabolic adaptation of epimastigotes inside the vector PMC12240186__F1 Mechanistic basis of XPO1 dependency ENSG00000061273 ENSG00000136997 ENSG00000168036 ENSG00000139687 PMC3554769__F1 Mathematical Model for MicroRNA in Lung Cancer ENSG00000136997 PMC8531217__F6 Sterols, Oxysterols, and Accessible Cholesterol: Signalling for Homeostasis, in Immunity and During Development ENSG00000132196 ENSG00000001630 ENSG00000116133 ENSG00000172893 ENSG00000149809 ENSG00000109929 ENSG00000036530 ENSG00000104549 PMC3958036__F9 Schematic model of how SH2B1B enhances gene expression and neuronal differentiation through STAT3 (step 1) ENSG00000178188 ENSG00000170558 ENSG00000077782 ENSG00000168610 PMC8000236__F6 Top predictive features for not mutated IGHV CLL patients ENSG00000163464 ENSG00000070831 PMC8531217__F1 Sterols, Oxysterols, and Accessible Cholesterol: Signalling for Homeostasis, in Immunity and During Development ENSG00000113161 ENSG00000104549 PMC7348140__F6 LncRNA NR2F1‐AS1 promoting breast cancer angiogenesis through IGF‐1/IGF‐1R/ERK pathway via sponging miRNA‐338‐3p ENSG00000140443 PMC4439933__F4 Detailed self-regulation scheme of cancer development in ERG+ well differentiated tumor samples ENSG00000157554 ENSG00000168036 ENSG00000155974 PMC8000236__F7 Top predictive features for IGHV-mutated CLL patients ENSG00000163464 ENSG00000070831 ENSG00000198793 PMC11936945__F1 TRAIL-DR5 related cell death regulation signaling pathway (Das et al ENSG00000278718 ENSG00000132906 ENSG00000110711 ENSG00000162711 ENSG00000092439 ENSG00000171791 ENSG00000127191 ENSG00000168610 ENSG00000164305 ENSG00000147697 ENSG00000149311 ENSG00000175054 ENSG00000120868 ENSG00000168404 ENSG00000064012 ENSG00000285379 PMC4220672__F1 Novel strategy for the use of leptin for obesity therapy ENSG00000168610 PMC8062588__F2 Cancer stem cells and strategies for targeted drug delivery ENSG00000002330 ENSG00000119888 ENSG00000074319 ENSG00000010278 ENSG00000118777 ENSG00000106459 ENSG00000149311 ENSG00000012048 ENSG00000168283 ENSG00000128272 ENSG00000136997 ENSG00000125538 ENSG00000135404 ENSG00000051180 ENSG00000100219 PMC8997719__F6 Total and Mitochondrial Transcriptomic and Proteomic Insights into Regulation of Bioenergetic Processes for Shoot Fast-Growth Initiation in Moso Bamboo ENSG00000172005 ENSG00000105953 ENSG00000062485 PMC6335102__F10 Renal ion regulation in response to ANG II ENSG00000126562 ENSG00000109062 ENSG00000080166 PMC5904535__F12 NF-Kb signaling pathway regulates cellular inflammatory, oxidative and apoptosis ENSG00000005381 ENSG00000026103 PMC11360101__F13 Actin Dysregulation Mediates Nephrotoxicity of Cassiae Semen Aqueous Extracts ENSG00000070831 PMC6335102__F13 ANG II signaling in aging ENSG00000198793 PMC8283198__F2 Role of Protein Kinase C in the Pathophysiology of Diabetes-Associated Atherosclerosis ENSG00000130164 ENSG00000162692 ENSG00000169174 PMC8265274__F3 F-Actin Dynamics in the Regulation of Endosomal Recycling and Immune Synapse Assembly ENSG00000109083 ENSG00000203485 ENSG00000070831 ENSG00000138175 ENSG00000134982 ENSG00000172005 ENSG00000169379 ENSG00000160050 ENSG00000109103 ENSG00000111737 ENSG00000292366 ENSG00000114520 PMC3334963__F7 Transcriptomics of In Vitro Immune-Stimulated Hemocytes from the Manila Clam Ruditapes philippinarum Using High-Throughput Sequencing ENSG00000183735 ENSG00000115415 ENSG00000137193 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000010671 PMC3334963__F8 Transcriptomics of In Vitro Immune-Stimulated Hemocytes from the Manila Clam Ruditapes philippinarum Using High-Throughput Sequencing ENSG00000132906 ENSG00000149089 ENSG00000142192 ENSG00000122966 ENSG00000102871 ENSG00000135472 ENSG00000165678 ENSG00000127191 ENSG00000026103 PMC9234462__F1 Structure Basis of Phytochemicals as Metabolic Signals for Combating Obesity ENSG00000183735 ENSG00000100473 ENSG00000136869 PMC9240418__F6 Molecular checkpoints of distorted autophagy pathways in lupus nephritis ENSG00000177169 ENSG00000123395 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000158828 ENSG00000145782 ENSG00000057663 PMC9227157__F3 Does Abiotic Host Stress Favour Dothideomycete-Induced Disease Development? ENSG00000115904 ENSG00000154059 ENSG00000100485 PMC8578927__F1 Making a Killer: Selecting the Optimal Natural Killer Cells for Improved Immunotherapies ENSG00000111537 ENSG00000143184 ENSG00000026103 PMC4280582__F4 Schematic representation of the HTRA2 protein and its activation against mitochondrial stress ENSG00000158828 ENSG00000115317 PMC4315929__F7 Cilia assembly and disassembly cycle ENSG00000094631 ENSG00000004975 ENSG00000182504 ENSG00000166851 PMC7847503__F7 Summarized molecular mechanisms of the signaling pathway involving the EGFR, TrkB, KRAS HIF-1A and VEGF-A genes; adapted from ENSG00000128272 ENSG00000138798 ENSG00000112715 ENSG00000146648 PMC6582778__F7 Proposed model of F ENSG00000111537 ENSG00000118520 PMC4718713__F5 Polycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic Implications ENSG00000168283 ENSG00000134982 ENSG00000168036 PMC4718713__F6 Polycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic Implications ENSG00000281766 ENSG00000121481 ENSG00000120868 ENSG00000168040 PMC2938100__F4 Connections of literature-completed interactome of PI3K-mTOR pathway with other signaling pathways ENSG00000198793 ENSG00000163914 PMC4043666__F7 Mass Spectrometry Based Identification of Geometric Isomers during Metabolic Stability Study of a New Cytotoxic Sulfonamide Derivatives Supported by Quantitative Structure-Retention Relationships ENSG00000180210 ENSG00000117525 ENSG00000198734 PMC3177269__F4 Proposed model for a common symbiotic signaling pathway between actinorhizal plants and legumes ENSG00000125450 ENSG00000069248 PMC11958682__F2 Rewired amino acid metabolism and FA metabolism in HCC ENSG00000131473 ENSG00000125166 ENSG00000151726 ENSG00000135218 ENSG00000060982 ENSG00000135069 ENSG00000103257 ENSG00000146733 ENSG00000070669 ENSG00000284320 ENSG00000092621 ENSG00000169507 ENSG00000118520 ENSG00000111371 ENSG00000036473 ENSG00000166123 ENSG00000105552 ENSG00000026103 ENSG00000084774 PMC4718713__F4 Polycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic Implications ENSG00000104856 ENSG00000291971 ENSG00000173039 PMC11958682__F3 Rewired acetyl-CoA metabolism and redox homeostasis in HCC ENSG00000111371 ENSG00000115419 PMC8024338__F8 MCPIP1-mediated NFIC alternative splicing inhibits proliferation of triple-negative breast cancer via cyclin D1-Rb-E2F1 axis ENSG00000135446 PMC3752952__F1 Pathomechanisms of LN outside the kidney ENSG00000092445 ENSG00000169896 ENSG00000203710 ENSG00000153064 ENSG00000152689 ENSG00000244731 ENSG00000185187 ENSG00000166278 ENSG00000143226 ENSG00000132693 ENSG00000117322 ENSG00000057663 ENSG00000177455 ENSG00000203747 ENSG00000213918 ENSG00000138378 ENSG00000115415 ENSG00000118503 ENSG00000184216 ENSG00000026103 PMC9127837__F5 Mitochondrial DNA Instability in Mammalian Cells ENSG00000012048 ENSG00000292286 ENSG00000138346 ENSG00000132781 ENSG00000051180 ENSG00000140398 ENSG00000177084 ENSG00000157036 PMC1682009__F1 Activation of the Akt pathway through binding of a ligand to a receptor, tyrosine kinase ENSG00000198793 PMC3563611__F8 Candidate miRNAs target genes involved in cell growth, survival, migration, and cell cycle progression ENSG00000002330 ENSG00000110395 ENSG00000046889 ENSG00000070831 ENSG00000095321 ENSG00000159388 ENSG00000135446 ENSG00000126457 ENSG00000123374 PMC4072696__F9 Integrative Identification of Deregulated MiRNA/TF-Mediated Gene Regulatory Loops and Networks in Prostate Cancer ENSG00000198793 ENSG00000123374 PMC9334593__F6 Pathway for glycine and serine biosynthesis in CC7-B01 response to heat stress ENSG00000002330 ENSG00000092621 ENSG00000146733 PMC4786553__F5 Top networks activated in the CPu during CIE and acute withdrawal ENSG00000147649 ENSG00000065320 ENSG00000134780 ENSG00000164082 ENSG00000007047 ENSG00000273686 ENSG00000004399 ENSG00000145934 ENSG00000186298 ENSG00000103942 ENSG00000211445 ENSG00000169220 ENSG00000117601 ENSG00000128052 ENSG00000136997 ENSG00000197386 ENSG00000291761 ENSG00000064012 ENSG00000276838 ENSG00000026103 PMC11187922__F9 The main findings in this study ENSG00000178860 ENSG00000110492 ENSG00000118785 ENSG00000111341 PMC5793173__F2 Transcription complexes induced by physiological and aberrant Wnt pathway activation ENSG00000134982 ENSG00000168036 ENSG00000089225 PMC6857109__F1 The E-cadherin (E-cad) interactions and signaling pathway ENSG00000065361 ENSG00000134982 ENSG00000168036 ENSG00000146648 PMC8429807__F3 Smoking and the Pathophysiology of Peripheral Artery Disease ENSG00000162711 ENSG00000144895 ENSG00000005381 ENSG00000096717 ENSG00000142082 PMC1860037__F1 Role of interleukin 6 in a murine model of Crohn's ileitis: are cytokine/anticytokine strategies the future for IBD therapies? ENSG00000168610 PMC7606466__F6 RNA-Seq reveals placental growth factor regulates the human retinal endothelial cell barrier integrity by transforming growth factor (TGFB) signaling ENSG00000142192 ENSG00000023734 ENSG00000169554 ENSG00000259207 ENSG00000111859 ENSG00000050748 ENSG00000115904 ENSG00000067900 ENSG00000081189 ENSG00000124762 ENSG00000160691 ENSG00000123124 ENSG00000182541 ENSG00000116750 ENSG00000140464 ENSG00000100603 PMC9880437__F1 Pyroptosis in neurodegenerative diseases and its therapeutic potential by traditional Chinese medicine ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000091106 PMC11352994__F7 Schematic overview of the B7-H4-mediated signalling pathway in trophoblast cells in patients with early-onset PE ENSG00000168610 PMC5793173__F3 Crosstalk between canonical and alternative Wnt signalling and the Hippo pathway ENSG00000281324 ENSG00000162337 ENSG00000163914 ENSG00000114978 ENSG00000150457 ENSG00000131023 PMC8150686__F1 Xmrks the Spot: Fish Models for Investigating Epidermal Growth Factor Receptor Signaling in Cancer Research ENSG00000010810 PMC4541496__F7 SKN-1 regulation in the GSC longevity pathway ENSG00000129347 ENSG00000133937 ENSG00000112561 PMC6213994__F6 Anti-oxidative signaling and anti-apoptosis signaling pathways ENSG00000079999 PMC8150686__F2 Xmrks the Spot: Fish Models for Investigating Epidermal Growth Factor Receptor Signaling in Cancer Research ENSG00000198793 PMC8446626__F2 Therapeutically Targeting Cancers That Overexpress FOXC1: A Transcriptional Driver of Cell Plasticity, Partial EMT, and Cancer Metastasis ENSG00000198793 ENSG00000121966 PMC8446626__F3 Therapeutically Targeting Cancers That Overexpress FOXC1: A Transcriptional Driver of Cell Plasticity, Partial EMT, and Cancer Metastasis ENSG00000127445 ENSG00000109320 ENSG00000138798 ENSG00000198793 ENSG00000173039 ENSG00000146648 PMC4552638__F8 Inhibition of mTORC1 Enhances the Translation of Chikungunya Proteins via the Activation of the MnK/eIF4E Pathway PMC7697769__F4A Gene Expression Signatures in AML-12 Hepatocyte Cells upon Dengue virus Infection and Acetaminophen Treatment ENSG00000282905 ENSG00000111537 ENSG00000105397 ENSG00000139546 ENSG00000177606 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000125347 ENSG00000175104 ENSG00000127191 ENSG00000164342 PMC4829114__F1 Metabolic pathway of P2Y12-receptor inhibitors ENSG00000115008 ENSG00000259207 ENSG00000005961 PMC8958338__F10 Heme-oxygenase and lipid mediators in obesity and associated cardiometabolic diseases: Therapeutic implications PMC8607308__F2 Infection with SARS-CoV-2 shows differential gene expression in Interleukin-6 signaling ENSG00000110395 ENSG00000105397 ENSG00000115415 ENSG00000168610 ENSG00000179295 PMC10340792__F2 Targeting transcription factor YY1 for antitumor therapy ENSG00000100811 ENSG00000284774 ENSG00000067057 ENSG00000284161 ENSG00000146648 ENSG00000026103 PMC8762348__F5 NMNAT3 regulating NAD+ in BMSCs to improve mitochondrial function and inhibit cell stress-induced apoptosis ENSG00000142082 PMC4075356__F6 An Irf6-dependent pathway regulating keratinocyte migration PMC5362152__F7 Schematic representation of the proposed model ENSG00000146648 PMC6214187__F1 SCAP/SREBPs Are Central Players in Lipid Metabolism and Novel Metabolic Targets in Cancer Therapy ENSG00000130164 ENSG00000113161 ENSG00000076555 ENSG00000096717 ENSG00000146648 ENSG00000026103 PMC4259449__F5 Characterization of single disseminated prostate cancer cells reveals tumor cell heterogeneity and identifies dormancy associated pathways ENSG00000074590 ENSG00000078900 ENSG00000072274 ENSG00000015285 ENSG00000220205 ENSG00000277273 ENSG00000168404 ENSG00000149187 ENSG00000001461 ENSG00000170516 PMC7902504__F1 Kinase pathways mediate dendritic morphogenesis and maturation ENSG00000106683 ENSG00000115977 ENSG00000149930 ENSG00000157540 ENSG00000142178 ENSG00000160551 ENSG00000138443 ENSG00000198793 ENSG00000143322 ENSG00000122545 PMC4632006__F1 Left: the PI3K/AKT/mTOR pathway is mainly activated by nutrients (not shown) and growth factors, binding to receptor tyrosine kinases and activating PI3K ENSG00000170365 ENSG00000169071 ENSG00000134982 ENSG00000198793 ENSG00000155792 ENSG00000168036 ENSG00000204217 PMC3025834__F1 Schematic representation of xylose metabolic pathway in metabolically engineered S ENSG00000197713 ENSG00000047597 ENSG00000158125 PMC3634196__F7 Summary diagram of the proposed mechanisms underlying CA3 hypersensitivity, Alzheimer’s disease protein induction, neuronal death and behavioural deficits following cerebral ischaemia in rats with LTED ENSG00000164879 ENSG00000177606 PMC5403663__F2 Enrichment of gene expression changes (p < 0.05) shared by the TCF4 small interfering RNA (siRNA)#1 and TCF4 siRNA#2 conditions in the “cell cycle” KEGG pathway (p = 0.006, Bonferroni-corrected) ENSG00000145604 ENSG00000108055 ENSG00000132646 ENSG00000123374 ENSG00000164754 ENSG00000277273 ENSG00000277943 ENSG00000117399 PMC3959159__F1 Major components of the TGF-ß signaling pathway ENSG00000132478 PMC8395387__F2 Pathophysiology of thrombosis in IBD ENSG00000281244 ENSG00000003436 ENSG00000110799 ENSG00000163737 ENSG00000122194 PMC8124719__F9 Antitumor Effects of 6-Gingerol in p53-Dependent Mitochondrial Apoptosis and Inhibition of Tumor Sphere Formation in Breast Cancer Cells ENSG00000291971 ENSG00000168610 ENSG00000146648 PMC8066561__F1 DNA double-strand break repair mechanisms and PARP inhibitor function ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000083093 ENSG00000144554 ENSG00000149554 ENSG00000138385 ENSG00000183765 PMC5033717__F1 Dll4-Notch Signaling in Macrophage Activation ENSG00000168214 ENSG00000148400 ENSG00000074181 PMC6385460__F1 The AMPK/mTOR signaling pathway in TNBC tumor growth and progression ENSG00000177169 ENSG00000291971 ENSG00000198793 ENSG00000167965 ENSG00000168610 ENSG00000146648 PMC5442421__F1 Simplified scheme of ‘the metabolic map of cancer cell' PMC6605314__F10 Schematic model of GPCR-mediated gene expression in neurons ENSG00000138166 ENSG00000122877 ENSG00000198576 ENSG00000105662 PMC4102378__F2 WNT signaling pathway ENSG00000291971 ENSG00000136997 ENSG00000168036 PMC4049637__F1 Functional Conservation of Coenzyme Q Biosynthetic Genes among Yeasts, Plants, and Humans ENSG00000132423 ENSG00000167113 ENSG00000119723 ENSG00000131238 ENSG00000110871 ENSG00000088682 ENSG00000173085 ENSG00000167186 PMC8604761__F1 Pyroptotic pathway in immune cells ENSG00000278718 ENSG00000162711 ENSG00000137275 ENSG00000125538 PMC7122831__F2 Terpene biosynthetic pathway in rose-scented geranium ENSG00000110921 ENSG00000197429 ENSG00000167508 ENSG00000082212 PMC4029595__F7 Proposed breast cancer signaling pathway based on the KEGG network pathway analysis of hypoxia-activated tumor cell migration ENSG00000070831 PMC10149994__F1 Reprogramming viral immune evasion for a rational design of next-generation vaccines for RNA viruses ENSG00000213928 ENSG00000088888 ENSG00000115415 PMC4227541__F2 CD40 stimulation stimulates a highly coordinated immune response by epithelial cells (ECs) ENSG00000144802 ENSG00000100906 PMC9125181__F7 Endothelial Beta-Catenin Deficiency Causes Blood-Brain Barrier Breakdown via Enhancing the Paracellular and Transcellular Permeability ENSG00000130300 ENSG00000281324 ENSG00000162337 ENSG00000174804 ENSG00000168036 PMC6702836__F6 Partial pathway reconstruction of genes involved in lipids, nucleotides and vitamins metabolism ENSG00000112977 ENSG00000173599 ENSG00000171759 PMC8094936__F8 Encephalomyocarditis Virus Abrogates the Interferon Beta Signaling Pathway via Its Structural Protein VP2 ENSG00000088888 ENSG00000131323 ENSG00000175104 PMC9302637__F2 Inhibitory Signaling at the Receptor and Cellular Level; Advances in Our Understanding of GABAergic Neurotransmission and the Mechanisms by Which It Is Disrupted in Epilepsy ENSG00000168610 PMC7580701__F1 Effect of environmental pollution on immune evasion checkpoints of SARS-CoV-2 ENSG00000111537 ENSG00000130234 ENSG00000184012 ENSG00000049768 ENSG00000168610 ENSG00000106546 PMC8478647__F2 External and internal signaling events on the surface of lysosomes ENSG00000177058 ENSG00000155792 ENSG00000141458 ENSG00000112561 ENSG00000189298 ENSG00000239282 ENSG00000011347 PMC11893431__F2 Molecular mechanism of SATB1 in breast cancer ENSG00000157764 ENSG00000182568 ENSG00000122691 ENSG00000198793 PMC6682621__F2 Polyamine metabolic pathway with differential expression genes and reporter metabolites highlighted ENSG00000088826 ENSG00000116649 ENSG00000102172 PMC5576761__F4 High activity of immune response ENSG00000095319 ENSG00000167720 ENSG00000108590 ENSG00000135069 ENSG00000180644 ENSG00000093009 ENSG00000100162 ENSG00000262634 ENSG00000111537 ENSG00000122952 ENSG00000167670 ENSG00000145649 ENSG00000041357 ENSG00000282899 PMC4231066__F6 Ethanol Negatively Regulates Hepatic Differentiation of hESC by Inhibition of the MAPK/ERK Signaling Pathway In Vitro ENSG00000019991 PMC6046302__F1 MAPK and PI3K/AKT/mTOR pathway interactions in melanocytic tumors ENSG00000157764 ENSG00000088256 PMC2709380__F7 Hypothetical model of transcriptional regulation of the p21 gene and p53 pathway ENSG00000181472 ENSG00000183337 ENSG00000185591 PMC7254954__F7 PLAG-induced TXNIP and MMP-9 expression in breast cancer cells ENSG00000110395 ENSG00000138798 ENSG00000265972 ENSG00000146648 PMC5701999__F3 Two arms of the insulin signaling pathway in skeletal muscle cells ENSG00000149269 ENSG00000220205 PMC9632296__F5 T-cells in head and neck squamous cell carcinoma: From immunity to immunotherapy ENSG00000158825 ENSG00000146648 PMC11480210__F3 14-3-3 proteins in the TNFR signaling pathway ENSG00000102871 ENSG00000198793 ENSG00000138032 ENSG00000056558 ENSG00000127191 PMC11480210__F4 14-3-3 proteins in bone biology ENSG00000139219 ENSG00000105664 ENSG00000157766 PMC6281172__F2 IFN-JAK-STAT signaling pathway ENSG00000141867 ENSG00000180182 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC11480210__F2 14–3-3 proteins in MAPK, PI3K/AKT, TGFB/Smad, Wnt/Beta-Catenin and Hippo/YAP signaling pathway ENSG00000134982 ENSG00000177606 ENSG00000168036 PMC5780129__F7 Co-expression network constructed for the signature genes ENSG00000110244 ENSG00000276559 ENSG00000160339 ENSG00000141744 ENSG00000143493 ENSG00000106927 ENSG00000137801 ENSG00000168875 ENSG00000150281 ENSG00000148082 ENSG00000145741 ENSG00000005187 ENSG00000108960 ENSG00000042429 ENSG00000074319 ENSG00000134595 ENSG00000166407 ENSG00000172809 ENSG00000174891 ENSG00000064545 ENSG00000176714 ENSG00000058262 ENSG00000114796 ENSG00000139597 ENSG00000135387 ENSG00000135272 ENSG00000182379 ENSG00000092978 ENSG00000066427 ENSG00000124253 PMC7097195__F2 Lysosomes as a therapeutic target ENSG00000112561 ENSG00000081087 PMC8036789__F4A Flavonoids Alleviate Peripheral Neuropathy Induced by Anticancer Drugs ENSG00000107562 ENSG00000136869 ENSG00000182606 PMC6089967__F2 Gene network of the susceptibility pathways/GO terms ENSG00000117971 ENSG00000159197 ENSG00000166862 ENSG00000152208 ENSG00000136531 ENSG00000072182 ENSG00000136160 ENSG00000198626 ENSG00000001626 ENSG00000122194 ENSG00000196689 ENSG00000080644 PMC4510598__F4 Fatty acids biosynthetic pathway (map 61) ENSG00000213614 ENSG00000169710 PMC7601465__F3 Transforming growth factorB signaling in a nutshell ENSG00000070831 PMC2807318__F8 Summary of the AMPK and mTOR signaling pathways ENSG00000198793 ENSG00000164327 PMC4650996__F8 TRPV1 antagonist-induced hyperthermia involves BAT-mediated thermogenesis ENSG00000042832 ENSG00000196689 PMC5836190__F3 Activation of the NLRP3 inflammasome in the canonical pathway ENSG00000162711 PMC5836190__F5 Alternative pathway of NLRP3 inflammasome activation ENSG00000162711 ENSG00000137275 ENSG00000168040 PMC2896632__F1 Signaling pathway of the KRAS protein ENSG00000198793 ENSG00000146648 PMC9316959__F3 Molecular Targets and Signaling Pathways of microRNA-122 in Hepatocellular Carcinoma ENSG00000114126 ENSG00000136997 PMC9316959__F4 Molecular Targets and Signaling Pathways of microRNA-122 in Hepatocellular Carcinoma ENSG00000167601 ENSG00000070831 ENSG00000136997 ENSG00000168036 ENSG00000146648 PMC7181582__F6 HIF signaling pathway and upregulated DEGs in HIF pathway from KEGG enrichment analysis of R ENSG00000134086 ENSG00000197872 ENSG00000198793 ENSG00000072274 ENSG00000088926 ENSG00000168610 PMC4392244__F9 Comparing CGN death induced by NSC23766 and ToxB ENSG00000038382 ENSG00000002330 ENSG00000070831 ENSG00000156299 ENSG00000149269 ENSG00000163914 PMC7967983__F2 Glycolysis in tumor and tumor microenvironment is associated with immunotherapy resistance ENSG00000198793 ENSG00000168036 ENSG00000125347 PMC7181582__F7 NFKB signaling pathway and upregulated DEGs in NFKB signaling pathway from KEGG enrichment analysis of R ENSG00000242689 ENSG00000102871 ENSG00000138798 ENSG00000111321 ENSG00000010671 ENSG00000095585 ENSG00000149311 ENSG00000226275 ENSG00000213658 ENSG00000170458 ENSG00000186716 ENSG00000131323 ENSG00000175104 ENSG00000121060 PMC9316959__F6 Molecular Targets and Signaling Pathways of microRNA-122 in Hepatocellular Carcinoma ENSG00000104812 ENSG00000141349 ENSG00000062485 PMC3801060__F6 Model of p21-mediated restriction of HIV-1 and related lentiviruses in macrophages PMC5836077__F4 Agrin stimulates integrin-FAK-ILK-PAK1 mechanosignalling pathway to antagonize the Hippo pathway and activate YAP/TAZ mediated gene transcription ENSG00000186575 ENSG00000149269 ENSG00000150457 ENSG00000131023 PMC8117390__F1 Polymorphisms in MicroRNA Target Sites of TGFB Signaling Pathway Genes and Susceptibility to Allergic Rhinitis PMC2000831__F3 Proliferation induced by androgen independent pathways ENSG00000163235 ENSG00000138798 PMC6470785__F5 Metabolic and signaling pathway crosstalk in tissues of animals with high inherent aerobic capacity (HIAC) and animals with low inherent aerobic capacity (LIAC) ENSG00000131473 ENSG00000291971 ENSG00000198793 ENSG00000169710 ENSG00000168610 ENSG00000140443 PMC5836077__F7 Concerted agrin and YAP activity in the maintenance of NMJs and promoting cardiac regeneration ENSG00000134569 ENSG00000030304 PMC12047509__F1 Nrf2 signaling in Alzheimer's Disease ENSG00000181019 ENSG00000167468 ENSG00000086991 ENSG00000023909 ENSG00000079999 PMC3615883__F1 G1 to S phase cell cycle transition regulators.Abbreviations: S, synthesis; G1, Gap 1 ENSG00000135446 ENSG00000136997 ENSG00000105810 PMC6935177__F9 Working model demonstrating the regulation of Hippo signaling during ovulation ENSG00000150457 ENSG00000131023 PMC3069071__F7 Hedgehog Inhibition Promotes a Switch from Type II to Type I Cell Death Receptor Signaling in Cancer Cells ENSG00000128602 PMC12092922__F4 MXRAs is involved in chemotherapy resistance ENSG00000291971 ENSG00000182534 ENSG00000162576 PMC5067469__F6 The signaling pathways of pathogen protective mechanisms based on HPCNs in Figure in Mϕs and DCs during Mtb infection ENSG00000172680 ENSG00000150991 ENSG00000124614 ENSG00000146648 ENSG00000062485 PMC6927934__F6 The cell cycle metaphase checkpoint pathway ENSG00000125817 ENSG00000117697 ENSG00000134982 ENSG00000166851 ENSG00000160783 ENSG00000117399 ENSG00000068028 ENSG00000117724 ENSG00000145604 ENSG00000094804 ENSG00000123374 ENSG00000062485 ENSG00000149503 PMC5940789__F6 MiRNA-gene-pathway network between sixteen intersection genes, and their corresponding pathways and differentially expressed miRNAs ENSG00000145604 ENSG00000087245 ENSG00000138794 ENSG00000203859 ENSG00000115942 PMC12092922__F2 Biological function of MXRAs ENSG00000147044 ENSG00000173269 ENSG00000291971 ENSG00000163914 ENSG00000139116 ENSG00000163453 ENSG00000182534 ENSG00000146648 PMC7372205__F1 ACE2/TMPRSS2 pathway and its interaction with SARS-CoV-2 ENSG00000130234 ENSG00000184012 PMC7372205__F2 COVID-19 early stage pharmacologic intervention targeting Sars-CoV-2 cell entry through the ACE2/TMPRSS2 pathway ENSG00000130234 ENSG00000184012 PMC7033461__F9 Upregulation of miR-101a Suppresses Chronic Renal Fibrosis by Regulating KDM3A via Blockade of the YAP-TGF-Beta-Smad Signaling Pathway ENSG00000115548 ENSG00000177426 PMC6307518__F1 HMGB1-RAGE/TLR-TNFA signaling pathway ENSG00000189403 ENSG00000136869 ENSG00000096717 PMC10870057__F1 Molecular regulatory mechanism of dormant cancer cells ENSG00000070831 ENSG00000134982 ENSG00000132646 ENSG00000198793 ENSG00000116741 ENSG00000142731 ENSG00000164039 PMC6333462__F1 Methyltransferases linked to regulation of autophagy ENSG00000145604 ENSG00000141867 ENSG00000103510 ENSG00000198793 ENSG00000142453 ENSG00000096717 ENSG00000082212 PMC10870057__F2 Molecular regulatory mechanisms of dormant PGCCs ENSG00000175054 ENSG00000070831 ENSG00000178999 ENSG00000175745 ENSG00000136997 ENSG00000087586 ENSG00000116741 PMC3298572__F7 Model for HuR NEDDylation ENSG00000167325 ENSG00000171848 ENSG00000285246 PMC4214130__F5 Hypothetical pathway analysis depicts mitochondrial dysfunction ENSG00000172840 ENSG00000005882 ENSG00000125538 PMC8721001__F1 Current Research Progress of the Role of LncRNA LEF1-AS1 in a Variety of Tumors ENSG00000138795 ENSG00000125398 ENSG00000168036 PMC7675715__F1 Sensitivity of cystic fibrosis transmembrane regulator (CFTR) carriers to COVID‐19 inflammatory response ENSG00000130234 ENSG00000125538 ENSG00000001626 PMC8721001__F2 Current Research Progress of the Role of LncRNA LEF1-AS1 in a Variety of Tumors ENSG00000138795 ENSG00000125398 ENSG00000198793 ENSG00000124766 ENSG00000026508 ENSG00000168036 PMC9094400__F1 Targeting PARP1 to Enhance Anticancer Checkpoint Immunotherapy Response: Rationale and Clinical Implications ENSG00000169245 ENSG00000164430 PMC9424672__F5 Cellular endocrinology mechanisms underlying the effects of Chinese herbal medicine therapy on asthma PMC5123368__F7 Schematic presentation shows the Adiponectin signaling pathway in neuron under normal (left) and disease (right) conditions ENSG00000142192 ENSG00000125538 ENSG00000169047 PMC5016670__F10 Signaling pathway by which TGFB1 increases DNMT1 and DNMT3a PMC9396537__F1 Cardiorenal protection of SGLT2 inhibitors—Perspectives from metabolic reprogramming ENSG00000135218 ENSG00000198793 ENSG00000096717 ENSG00000142082 ENSG00000275544 PMC5993212__F7 Commonalities in epileptogenic processes from different acute brain insults. Does it translate? ENSG00000198793 ENSG00000189403 ENSG00000172936 ENSG00000124181 ENSG00000175104 ENSG00000184216 PMC5105987__F11 PoCos: Population Covering Locus Sets for Risk Assessment in Complex Diseases ENSG00000158458 ENSG00000148308 ENSG00000111666 ENSG00000139351 ENSG00000111670 ENSG00000178568 PMC5105987__F12 PoCos: Population Covering Locus Sets for Risk Assessment in Complex Diseases ENSG00000130706 ENSG00000070814 ENSG00000148019 ENSG00000113722 ENSG00000276996 ENSG00000187672 PMC11468018__F5 Proposed signaling pathway illustrating effects of cancer and inflammation in the kidney ENSG00000102871 ENSG00000172936 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC7801705__F6 NOD2 deficiency increases retrograde transport of secretory IgA complexes in Crohn’s disease ENSG00000102189 ENSG00000167207 ENSG00000124839 PMC7185074__F6 ‘mTOR signaling pathway’ ENSG00000168003 ENSG00000198793 ENSG00000155792 PMC9396537__F4 Cardiorenal protection of SGLT2 inhibitors—Perspectives from metabolic reprogramming ENSG00000198793 ENSG00000096717 ENSG00000142082 ENSG00000026103 PMC4055208__F8 Scheme representing the insulin signalling pathway, the mechanisms involved in the high glucose-induced impairment of the insulin pathway and the proposed mechanism by which PPARB agonists prevent high glucose-induced insulin resistance in HUVECs ENSG00000169047 PMC4774549__F4 Ubiquitination in the Antiviral Immune Response ENSG00000164430 ENSG00000119401 ENSG00000169871 ENSG00000173456 PMC4777718__F2 A view of L-homoserine biosynthesis pathway page ENSG00000148798 ENSG00000132341 PMC3878307__F1 TMEFF2 AND SARDH COOPERATE TO MODULATE ONE CARBON METABOLISM AND INVASION OF PROSTATE CANCER CELLS ENSG00000144339 ENSG00000178445 PMC10940682__F10 Glycosylphosphatidylinositol anchor proteins (GPI-APs) play a role in several cellular signal transduction pathways ENSG00000139193 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000168610 ENSG00000146648 ENSG00000110195 ENSG00000156535 PMC4303155__F2 MAPK signaling pathway showing the target genes of microRNAs ENSG00000170458 ENSG00000138798 ENSG00000130159 PMC11730190__F4 Action of DPEP1 in malignant tumors ENSG00000183734 ENSG00000198793 ENSG00000136997 ENSG00000146648 PMC5400654__F1 Involvement of inflammation and its related microRNAs in hepatocellular carcinoma ENSG00000169554 ENSG00000168214 ENSG00000198742 ENSG00000170558 ENSG00000168036 PMC9277720__F2 Digesting the Role of JAK-STAT and Cytokine Signaling in Oral and Gastric Cancers ENSG00000115415 ENSG00000105639 ENSG00000127191 ENSG00000168610 PMC5400654__F4 Involvement of inflammation and its related microRNAs in hepatocellular carcinoma ENSG00000104856 ENSG00000102871 ENSG00000082512 ENSG00000172936 ENSG00000111321 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC7226610__F4 P53-related miRNAs controls the osteoblastic differentiation through interplay with Notch, Wnt/Beta-catenin, and Sonic/Hedgehog (HH) pathways ENSG00000138795 ENSG00000148400 ENSG00000130522 ENSG00000168036 ENSG00000112715 ENSG00000128602 PMC4180468__F10 A model for action of DOX within key signaling pathways necessary for LTF PMC3571707__F1 Adaptive Immune Responses and HER2/neu Positive Breast Cancer ENSG00000189403 ENSG00000172936 PMC9657949__F1 MicroRNAs in HER2-Positive Breast Cancer: Where We Are and Future Prospective ENSG00000169047 PMC7340853__F1 Clinical promise of next-generation complement therapeutics ENSG00000039537 ENSG00000009724 ENSG00000113600 ENSG00000134830 ENSG00000291559 ENSG00000288512 ENSG00000203710 ENSG00000196352 ENSG00000117335 ENSG00000244731 ENSG00000182326 PMC9663521__F7 Protein tyrosine kinase 6 regulates activation of SRC kinase ENSG00000291971 ENSG00000146648 ENSG00000101213 PMC5369246__F1 Signaling pathways of ATM and ATRThe DNA damage response is activated by ATM, ATR, and DNA-PKcs ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000113456 ENSG00000112242 ENSG00000144554 ENSG00000051180 ENSG00000282899 ENSG00000138385 PMC5369246__F3 STAT-5-dependent activation of ATM and ATR pathways, required for HPV genome amplificationHigh-risk HPV activates STAT-5 to mediate TopBP1 transcriptionally to promote ATR pathway ENSG00000149311 ENSG00000175054 ENSG00000115415 PMC5199628__F1 Principles of Kinase Inhibitor Therapy for Solid Tumors ENSG00000157404 ENSG00000198793 ENSG00000146648 PMC2563957__F1 Phospholipase A2 (PLA2) catalyzes phosphatidylcholine into AA in response to agonist stimulation of a G-protein–coupled cell surface receptor ENSG00000166278 PMC6590704__F1 Nuclear gene-encoded regulatory factors are essential for mitochondrial biogenesis and function ENSG00000096717 ENSG00000106459 PMC3120887__F5 MicroRNA Expression Profiling Reveals MiRNA Families Regulating Specific Biological Pathways in Mouse Frontal Cortex and Hippocampus ENSG00000276825 ENSG00000152266 ENSG00000184845 ENSG00000002330 ENSG00000169676 ENSG00000095321 ENSG00000107130 ENSG00000177606 ENSG00000095015 ENSG00000065559 ENSG00000035681 ENSG00000149295 PMC4724176__F2 Molecular signaling and the advantages of Warburg ENSG00000140992 ENSG00000019991 ENSG00000138798 ENSG00000159399 PMC7730716__F1 Schematic image of TGFB/SMAD and BMP/SMAD signaling pathway in fibrosis (upper left box, signal activation via TGFB receptor and ligand attachment; orange and yellow circles/arrows, TGFB ligands/signaling and BMP ligands/signaling, respectively) ENSG00000170365 PMC8469693__F5 NFKB and Pancreatic Cancer; Chapter and Verse ENSG00000104856 ENSG00000239732 ENSG00000102871 ENSG00000187554 ENSG00000134070 ENSG00000157625 ENSG00000136869 ENSG00000162924 ENSG00000127191 ENSG00000184216 PMC9503372__F9 Disruption of the Chitin Biosynthetic Pathway Results in Significant Changes in the Cell Growth Phenotypes and Biosynthesis of Secondary Metabolites of Monascus purpureus ENSG00000159224 ENSG00000120805 ENSG00000026103 PMC7730716__F2 Therapeutic target sites in the TGFB/BMP signaling pathway ENSG00000170365 PMC6679009__F2 Canonical WNT/Beta-catenin pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8469693__F3 NFKB and Pancreatic Cancer; Chapter and Verse ENSG00000104856 ENSG00000186716 ENSG00000111321 PMC11965140__F7 Immune regulation of CORT depends on GR signaling and 11Beta-HSD ENSG00000150907 ENSG00000198793 ENSG00000118520 PMC11889768__F1 Biosynthetic pathway of 2-AP ENSG00000100033 PMC11965140__F5 Immune activity by CORT through TREM2 ENSG00000162711 ENSG00000197943 ENSG00000172936 ENSG00000168610 PMC11965140__F6 Multiple pathways mediate the inflammatory injury of CORT induced cell death ENSG00000278718 ENSG00000167601 ENSG00000162711 ENSG00000153208 ENSG00000128917 ENSG00000136997 ENSG00000112561 ENSG00000136869 ENSG00000100219 ENSG00000184500 ENSG00000138081 PMC10309559__F2 IFNB expression: focusing on the role of its promoter and transcription regulators ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000115415 ENSG00000172936 ENSG00000175104 PMC11965140__F3 Immune activation and immune imbalance induced by CORT ENSG00000149311 ENSG00000162711 ENSG00000102962 ENSG00000275385 ENSG00000137033 ENSG00000122223 ENSG00000125538 ENSG00000198793 ENSG00000102970 ENSG00000163565 PMC3603375__F4 Neurotrophin signaling pathway is among the pathways downregulated in clinical T1 and upregulated in clinical T2 ENSG00000181195 PMC3894494__F7 Proposed model of heme-induced stasis ENSG00000170458 ENSG00000110799 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000162692 PMC3342348__F1 IL-1 signaling in the tumor microenvironment ENSG00000172936 ENSG00000175104 PMC3806061__F1 Diagrammatic representation of the hedgehog (Hh) signaling pathway ENSG00000164161 ENSG00000171791 ENSG00000128602 PMC9093608__F7 Bioinformatics Analysis of Publicly Available Single-Nuclei Transcriptomics Alzheimer’s Disease Datasets Reveals APOE Genotype-Specific Changes Across Cell Types in Two Brain Regions ENSG00000156687 ENSG00000110711 ENSG00000157766 ENSG00000169783 ENSG00000107731 ENSG00000179915 ENSG00000292254 PMC10035050__F6 Sodium acetate regulates milk fat synthesis through the activation of GPR41/GPR43 signaling pathway ENSG00000169710 ENSG00000285482 PMC5468686__F2 Protective or pathogenic roles of innate lymphoid cells (ILCs) in liver diseases ENSG00000162594 ENSG00000137033 ENSG00000134982 ENSG00000138755 ENSG00000131724 ENSG00000049768 ENSG00000168610 PMC5920772__F3 Development and Connectivity of the Habenular Nuclei ENSG00000153993 ENSG00000164690 PMC11011033__F3 NDRGs in Breast Cancer: A Review and In Silico Analysis ENSG00000118515 ENSG00000146648 PMC8079203__F8 PI3K/AKT/mTOR and autophagy signal pathway ENSG00000087245 ENSG00000198793 ENSG00000100985 ENSG00000057663 PMC9203688__F1 Ferroptosis and Autoimmune Diseases ENSG00000167468 ENSG00000189403 PMC4988275__F1 Cellular and molecular events of autophagy–lysosomal pathway ENSG00000152348 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC3684083__F4 EGFR/TGFA and TGFB/CTGF Signaling in Neuroendocrine Neoplasia: Theoretical Therapeutic Targets ENSG00000163235 ENSG00000138798 ENSG00000198793 PMC3684083__F2 EGFR/TGFA and TGFB/CTGF Signaling in Neuroendocrine Neoplasia: Theoretical Therapeutic Targets ENSG00000157764 ENSG00000198793 PMC3684083__F1 EGFR/TGFA and TGFB/CTGF Signaling in Neuroendocrine Neoplasia: Theoretical Therapeutic Targets ENSG00000157764 ENSG00000291972 ENSG00000163235 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC11821961__F1 Two NFKB signaling pathways include the classical (canonical) and alternative (noncanonical) routes ENSG00000104856 ENSG00000102871 ENSG00000173039 ENSG00000111321 ENSG00000150455 ENSG00000127191 ENSG00000010671 ENSG00000095585 ENSG00000226275 ENSG00000213658 ENSG00000186716 ENSG00000082512 ENSG00000172936 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000184216 PMC8602792__F4 Novel Therapeutic Targets in Liver Fibrosis ENSG00000128602 PMC7082882__F3 How PHB1 exerts tumor suppression in the liver ENSG00000178573 ENSG00000102974 PMC7799025__F1 IL-6 receptor and signaling ENSG00000033327 ENSG00000131323 ENSG00000168610 PMC12160120__F3 Mechanism and effects of the cGAS-STING pathway in regulating antitumor immunity across T cell subsets ENSG00000123685 ENSG00000139193 ENSG00000183735 ENSG00000164430 ENSG00000107485 ENSG00000049768 ENSG00000007171 PMC12160120__F4 CGAS-STING pathway regulates TAM polarization and anti-tumor immune effect ENSG00000081041 ENSG00000164430 ENSG00000115415 ENSG00000112561 PMC12160120__F5 CGAS-STING interaction network with other immune cells and its regulatory role in tumor immunity ENSG00000164430 ENSG00000138755 ENSG00000173599 ENSG00000284161 ENSG00000129226 ENSG00000118520 ENSG00000168610 PMC8736280__F1 Vasculopathy in COVID-19 ENSG00000160752 ENSG00000134982 ENSG00000130234 ENSG00000173599 ENSG00000173786 ENSG00000127528 ENSG00000196352 ENSG00000122194 ENSG00000062485 PMC11899857__F7 NFATc1 plays a central role in regulating the expression of downstream genes and proteins, including CTSK, MMP9, DCstamp, integrin B3, ATP6v0d2, and ACP5 ENSG00000147614 ENSG00000164935 ENSG00000102575 ENSG00000100985 ENSG00000131196 ENSG00000143387 PMC12160120__F6 Interactions and regulatory mechanisms between the cGAS-STING pathway and other components within the TIME ENSG00000169245 ENSG00000183735 ENSG00000115415 ENSG00000138755 ENSG00000168610 PMC2082128__F7 Biosynthetic pathway for the ganglio-series of glycosphingolipids ENSG00000135454 ENSG00000111728 ENSG00000101638 ENSG00000115525 PMC12160120__F7 Synergistic Mechanisms and Translational Potential of cGAS-STING Pathway Combined with Other Therapies PMC8758994__F1 De novo lipogenesis ENSG00000131473 ENSG00000079432 ENSG00000026103 PMC4703083__F5 The proposed biosynthetic and maintenance pathways for the metallocofactors of the class Ia (a), Ib (b), and Ic (c) ribonucleotide reductases ENSG00000163497 ENSG00000088926 PMC8557169__F4 Turning scientific serendipity into discoveries in breast cancer research and treatment: a tale of PhD students and a 50-year roaming tamoxifen team ENSG00000168040 PMC9497596__F7 Full-Length Transcriptome Sequencing Combined with RNA-Seq to Analyze Genes Related to Terpenoid Biosynthesis in Cinnamomum burmannii ENSG00000110921 ENSG00000197429 ENSG00000082212 PMC8758994__F3 Physiological regulation of DNL ENSG00000131473 ENSG00000079432 ENSG00000026103 PMC3929107__F1 Regulation of Hippo pathway and implications for anticancer drug development ENSG00000163914 ENSG00000198670 ENSG00000150457 ENSG00000131023 PMC12160120__F1 CGAS-STING signaling pathway mechanism ENSG00000183735 ENSG00000164430 ENSG00000167323 PMC12160120__F2 Mechanisms and Roles of cGAS-STING Pathway in Regulating DC Subpopulations for Antitumor Immunity ENSG00000139193 ENSG00000169245 ENSG00000164430 ENSG00000138755 ENSG00000173578 ENSG00000126353 ENSG00000277943 PMC4303659__F10 Working hypothesis for how the PGRN/PIRO axis regulates the formation of multinucleated osteoclasts ENSG00000170909 ENSG00000175104 ENSG00000131196 PMC2390572__F10 MCF10A Pathway 2 affected by TFIIS knockdown ENSG00000129219 ENSG00000065613 ENSG00000078369 ENSG00000129946 ENSG00000169136 ENSG00000087074 ENSG00000186480 ENSG00000162892 ENSG00000111142 ENSG00000274665 ENSG00000285456 ENSG00000162188 PMC6054955__F4 Immune Responses of Epinephelus coioides to sigX ENSG00000039537 ENSG00000186716 ENSG00000121966 PMC8466051__F2 VAV Proteins as Double Agents in Cancer: Oncogenes with Tumor Suppressor Roles ENSG00000168214 ENSG00000148400 ENSG00000141968 PMC8070086__F6 Putative mechanisms of TRIB3-mediated AKT signaling inhibition ENSG00000002330 ENSG00000101255 ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC4363166__F4 An extended signaling pathway that regulates basal P-glycoprotein activity at the blood-brain barrier ENSG00000198793 ENSG00000170989 PMC11465851__F3 Pattern recognition receptors on ependymal cells are involved in inflammatory signaling The TLR4/MyD88/NFKB signaling pathway induces the release of inflammatory cytokines like IL-1B and TNFA, while promoting phagocytic apoptosis ENSG00000239732 ENSG00000170458 ENSG00000129654 ENSG00000172936 ENSG00000136869 PMC6679009__F5 Beneficial role of NSAIDs in cancer process ENSG00000134982 ENSG00000168610 PMC6562376__F1 B1 integrin induces EGFR- or HER (ErbB2)-targeted therapy resistance ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC6562376__F3 B3/KRAS/RalB/NFkB pathway mediates EGFR-targeted therapy resistance ENSG00000138798 ENSG00000144118 ENSG00000146648 PMC3649103__F2 Hepatic ethanol metabolism ENSG00000042832 ENSG00000169047 ENSG00000026103 PMC9501546__F5 TTYH3 Modulates Bladder Cancer Proliferation and Metastasis via FGFR1/H-Ras/A-Raf/MEK/ERK Pathway ENSG00000136295 ENSG00000077782 PMC3763909__F2 The role of androgens/AR in acne formation/progression ENSG00000150907 PMC3649103__F1 Hepatic glucose metabolism ENSG00000042832 ENSG00000150907 ENSG00000169047 ENSG00000026103 PMC8976637__F2 Disease: Recessive ADAMTSL4 Mutations and Craniosynostosis with Ectopia Lentis ENSG00000157933 ENSG00000166147 ENSG00000062485 PMC8427595__F7 Dengue Virus Dysregulates Master Transcription Factors and PI3K/AKT/mTOR Signaling Pathway in Megakaryocytes ENSG00000198793 ENSG00000179348 PMC8938628__F12 Design, synthesis and evaluation of 4,7-disubstituted 8-methoxyquinazoline derivatives as potential cytotoxic agents targeting Beta-catenin/TCF4 signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC3429047__F5 Simplified illustration of the canonical Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC2747168__F1 Acp-group transfer catalyzed by PhTYW2 ENSG00000198874 PMC8863366__F1 Blocking cholesterol storage to treat Alzheimer’s disease ENSG00000119655 ENSG00000141458 ENSG00000075239 PMC7249037__F5 KEGG pathway for ovarian cancer ENSG00000149311 ENSG00000213658 ENSG00000196549 ENSG00000136997 ENSG00000069667 ENSG00000062485 PMC7249037__F6 KEGG pathway for colorectal cancer ENSG00000132906 ENSG00000002330 ENSG00000109321 ENSG00000134982 ENSG00000198793 ENSG00000177606 ENSG00000146648 ENSG00000164305 ENSG00000122008 PMC5743003__F1 Signaling pathways involved in the pathogenesis of MPNs and secondary AML ENSG00000171456 ENSG00000117400 ENSG00000198793 ENSG00000187266 PMC7249037__F7 KEGG pathway for breast cancer ENSG00000169291 ENSG00000177084 ENSG00000132341 PMC3107100__F1 Genetic alterations in glioblastoma signal transduction pathways (adapted from Parsons et al) ENSG00000291971 ENSG00000146648 ENSG00000196712 PMC9961805__F1 E’Jiao on Skeletal Mineralisation, Osteocyte and WNT Signalling Inhibitors in Ovariectomised Rats ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 PMC3868343__F2 Molecular basis for synergistic activation through pairs of coactivation receptors on NK cells ENSG00000110395 ENSG00000010810 PMC9030606__F1 Theophylline: Old Drug in a New Light, Application in COVID-19 through Computational Studies ENSG00000143799 ENSG00000162711 ENSG00000088888 ENSG00000167207 ENSG00000105397 ENSG00000130234 ENSG00000196591 ENSG00000276561 ENSG00000060762 PMC10814280__F1 RABV-induced incomplete autophagy ENSG00000177169 ENSG00000144848 ENSG00000142089 ENSG00000145782 PMC10221447__F3 Natural Products Targeting PI3K/AKT in Myocardial Ischemic Reperfusion Injury: A Scoping Review PMC3907121__F1 Cardiovascular Effects of Erythropoietin: An Update ENSG00000002330 ENSG00000186716 ENSG00000187266 ENSG00000168610 PMC2917029__F8 Molecular pathway initiated by P4 signaling in BPBC cells ENSG00000138798 ENSG00000146648 PMC8018074__F8 Complement C3a induces axonal hypomyelination in the periventricular white matter through activation of WNT/B‐catenin signal pathway in septic neonatal rats experimentally induced by lipopolysaccharide ENSG00000184221 ENSG00000134982 ENSG00000197971 ENSG00000125538 ENSG00000168036 ENSG00000205927 ENSG00000100146 ENSG00000168646 ENSG00000196628 PMC3667241__F1 Schematic drawings of the neuronal signaling pathways of anorexigenic and anxiogenic-like action in goldfish ENSG00000125787 PMC7675040__F4 Alteration in DNA repair mechanism in esophageal cells chronically treated with cigarette smoke condensate ENSG00000149311 ENSG00000175054 ENSG00000104689 ENSG00000090061 ENSG00000078900 ENSG00000092853 ENSG00000132646 ENSG00000125686 ENSG00000123374 ENSG00000174197 ENSG00000253729 ENSG00000183765 PMC11593047__F3 Contribution of Sox17-induced gene products to the maintenance of the hematopoietic capacity and cluster formation ENSG00000149564 ENSG00000102145 ENSG00000164736 ENSG00000159216 ENSG00000148400 ENSG00000285438 ENSG00000114315 ENSG00000179348 ENSG00000203883 PMC3432190__F2 Concept of molecular network in schizophrenia ENSG00000121207 ENSG00000070831 ENSG00000291971 ENSG00000138798 ENSG00000186141 ENSG00000165527 ENSG00000100033 ENSG00000112715 ENSG00000136826 ENSG00000196628 ENSG00000129219 ENSG00000170890 ENSG00000188313 ENSG00000136997 ENSG00000173599 ENSG00000059573 ENSG00000130402 ENSG00000113520 ENSG00000118520 ENSG00000124181 ENSG00000140287 ENSG00000073756 ENSG00000187758 ENSG00000146648 ENSG00000084774 PMC10421513__F10 Structure Characterization and Immunomodulatory Activity of Misgurnus anguillicaudatus Carbohydrates ENSG00000177606 ENSG00000172936 ENSG00000130159 ENSG00000150455 ENSG00000175104 PMC6479730__F1 General representation of the signaling pathways involved in the antagonism of both ionotropic and metabotropic glutamate receptors in anti-cancer mediated effects ENSG00000170365 ENSG00000198793 PMC8238076__F5 Celastrol Modulates Multiple Signaling Pathways to Inhibit Proliferation of Pancreatic Cancer via DDIT3 and ATF3 Up-Regulation and RRM2 and MCM4 Down-Regulation ENSG00000159921 ENSG00000121068 ENSG00000109321 ENSG00000143970 ENSG00000178999 ENSG00000291761 ENSG00000133961 ENSG00000162772 PMC8238076__F6 Celastrol Modulates Multiple Signaling Pathways to Inhibit Proliferation of Pancreatic Cancer via DDIT3 and ATF3 Up-Regulation and RRM2 and MCM4 Down-Regulation ENSG00000175054 ENSG00000276876 PMC6792082__F7 Targeting NRF2 antioxidant pathway for IDH1-mutated cancers ENSG00000065833 ENSG00000178573 ENSG00000023909 ENSG00000079999 PMC10373932__F5 Insights into the physiological and genomic characterization of three bacterial isolates from a highly alkaline, terrestrial serpentinizing system ENSG00000145020 PMC8161999__F6 Identification of circRNA–miRNA–mRNA networks contributes to explore underlying pathogenesis and therapy strategy of gastric cancer ENSG00000177455 ENSG00000103479 ENSG00000142192 ENSG00000101474 ENSG00000090402 ENSG00000002330 ENSG00000102871 ENSG00000173599 ENSG00000198517 ENSG00000177084 ENSG00000026103 PMC11555182__F1 KEAP1-NFE2L2 signaling pathway ENSG00000116044 ENSG00000100387 ENSG00000079999 PMC11711403__F9 Model depicting PBLD and Cedrelone inhibit viral replication via activating the NFKB-mediated IFN-I signaling response ENSG00000132109 ENSG00000213928 PMC9160962__F1 Methyl Metabolism and the Clock: An Ancient Story With New Perspectives ENSG00000228716 ENSG00000065911 ENSG00000282739 ENSG00000103707 ENSG00000173638 ENSG00000163738 ENSG00000145293 ENSG00000164933 ENSG00000120254 ENSG00000178445 ENSG00000149089 ENSG00000100714 ENSG00000136371 ENSG00000124275 ENSG00000091140 ENSG00000164904 ENSG00000136877 ENSG00000132840 ENSG00000102172 ENSG00000076351 ENSG00000116984 ENSG00000284320 ENSG00000158467 ENSG00000151224 ENSG00000160282 ENSG00000123505 ENSG00000182551 ENSG00000116649 ENSG00000110195 ENSG00000116761 ENSG00000016391 PMC9355787__F1 COL1A2, AKT3 genes, and related signaling pathway in the pathology of congenital talipes equinovarus ENSG00000117020 ENSG00000198793 PMC3287489__F2 Cell cycle pathway and the significant genes on cell cycle-related miRNAs ENSG00000145604 ENSG00000132646 ENSG00000123374 ENSG00000277273 ENSG00000117399 PMC3978385__F3 NRAS mutant melanoma: biological behavior and future strategies for therapeutic management ENSG00000157764 PMC3787923__F2 The role of chemotherapy and latest emerging target therapies in anaplastic thyroid cancer ENSG00000198793 ENSG00000146648 PMC11555182__F2 NFE2L2-dependent genes in ferroptosis ENSG00000138449 ENSG00000151012 ENSG00000116044 ENSG00000066926 ENSG00000072274 ENSG00000008394 ENSG00000115657 ENSG00000168003 ENSG00000125144 ENSG00000181019 ENSG00000167468 ENSG00000167996 ENSG00000042286 ENSG00000087842 PMC8144126__F9 Gut-liver axis modulation of Panax notoginseng saponins in nonalcoholic fatty liver disease ENSG00000042832 ENSG00000170458 ENSG00000172936 ENSG00000136869 PMC5007850__F7 Diagram summarizing the proposed mechanism by which MACC1 drives resistance to trastuzumab ENSG00000183742 ENSG00000159399 PMC6372189__F3 A combined computational strategy of sequence and structural analysis predicts the existence of a functional eicosanoid pathway in Drosophila melanogaster ENSG00000108839 ENSG00000161905 ENSG00000179593 ENSG00000275565 PMC8640456__F3 An Integrated Analysis Reveals Geniposide Extracted From Gardenia jasminoides J.Ellis Regulates Calcium Signaling Pathway Essential for Influenza A Virus Replication ENSG00000182533 ENSG00000130528 ENSG00000156026 ENSG00000186716 PMC5689670__F8 Baicalein inhibits progression of osteosarcoma cells through inactivation of the Wnt/Beta-catenin signaling pathway ENSG00000087245 ENSG00000135446 ENSG00000168036 ENSG00000100985 PMC6923843__F5 Gene functional and Network pathway analysis of TRAP1, HSPD1, HSPB1, HSPA1L and HSPA1A PMC9032823__F7 Metabolism of the Genus Guyparkeria Revealed by Pangenome Analysis ENSG00000197713 PMC3627964__F2 Proposed roles of Msi1-like (MSIL) proteins as regulators of the nutrient- and stress-sensing signaling pathways in fungi ENSG00000188895 ENSG00000070831 ENSG00000135097 PMC8250137__F3 COVID-19 Severity in Obesity: Leptin and Inflammatory Cytokine Interplay in the Link Between High Morbidity and Mortality ENSG00000169047 ENSG00000168610 PMC4095859__F3 Metabolic requirements for the maintenance of self-renewing stem cells ENSG00000198793 ENSG00000169710 ENSG00000140464 PMC5668879__F10 Proposed effect of polyP and retinol on the expression of the fatty acid binding protein 4 (FABP4) and leptin/leptin receptor ENSG00000128917 ENSG00000150907 ENSG00000198793 ENSG00000112715 PMC4095859__F4 Metabolic requirements for the maintenance of self-renewing stem cells ENSG00000149311 ENSG00000241186 ENSG00000198793 PMC3061506__F1 Integration of the identified proteins into the canonical pathway of TLR signaling ENSG00000177606 PMC9202997__F3 Impact of Air Pollution on the Course of Cystic Fibrosis: A Review ENSG00000149311 ENSG00000002330 ENSG00000119608 ENSG00000214285 ENSG00000001626 PMC3626841__F4 Original model by Neumann et al ENSG00000168040 ENSG00000064012 ENSG00000164305 PMC2667788__F3 Paracrine mechanisms in adult stem cell signaling and therapy ENSG00000154342 ENSG00000019991 ENSG00000002330 ENSG00000168036 ENSG00000131477 ENSG00000168610 PMC5716829__F1 Different PPGL molecular subgroups with corresponding driver mutations and a proportion of hereditary disease in the respective cluster ENSG00000135956 ENSG00000143252 ENSG00000134086 ENSG00000073578 ENSG00000117118 ENSG00000198793 ENSG00000136997 ENSG00000196782 ENSG00000009307 ENSG00000196712 ENSG00000167985 PMC7576599__F1 Emerging role of the Hippo pathway in autophagy ENSG00000177169 ENSG00000123395 ENSG00000126775 ENSG00000144848 ENSG00000157954 ENSG00000145782 PMC10373173__F2 Matrix metalloproteinases in rheumatoid arthritis and osteoarthritis: a state of the art review ENSG00000136997 PMC6428091__F1 Cytosolic glucose enters glycolysis and pentose phosphate pathways ENSG00000157911 ENSG00000198670 ENSG00000034693 ENSG00000026103 PMC8360179__F5 Plastidial acyl carrier protein Δ9‐desaturase modulates eicosapentaenoic acid biosynthesis and triacylglycerol accumulation in Phaeodactylum tricornutum ENSG00000173599 ENSG00000198670 PMC5678884__F9 Kojic acid-mediated damage responses induce mycelial regeneration in the basidiomycete Hypsizygus marmoreus ENSG00000070831 PMC4810057__F2 The signaling network of JAK/STATs in IBD ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000105639 ENSG00000168610 PMC7359838__F1 Spliceosome pathway (hsa/dre03040) as enriched in module ME01 (Bonferroni correction < .05) ENSG00000162385 ENSG00000085872 ENSG00000021776 ENSG00000086589 ENSG00000179950 ENSG00000124380 ENSG00000240682 ENSG00000164609 PMC11595780__F4 Intratumoral microbiota promotes tumorigenesis and tumor progression through several mechanisms ENSG00000168036 ENSG00000168610 PMC6209728__F2 Osteocyte role in MM bone disease ENSG00000281324 ENSG00000162337 PMC10814280__F2 : promotion : inhabition ENSG00000171791 PMC7588592__F2 New molecular targeted drugs ENSG00000146469 ENSG00000146648 PMC6770025__F1 Synthesis of steroid hormones in humans ENSG00000086696 ENSG00000108786 ENSG00000277893 ENSG00000203859 ENSG00000127948 PMC4184910__F1 Schematic diagram and proposed model for the metabolic regulation and coordination of the leptin mediated reproductive and nutritional axes ENSG00000171105 ENSG00000198576 ENSG00000115138 ENSG00000166603 PMC9688847__F1 Stemness of Normal and Cancer Cells: The Influence of Methionine Needs and SIRT1/PGC-1A/PPARA Players ENSG00000284320 ENSG00000099810 ENSG00000116649 ENSG00000178445 ENSG00000102172 ENSG00000116984 PMC5649203__F2 Metabolic requirements of effector CD8+ T cells (Teff) ENSG00000135218 ENSG00000198793 PMC9412206__F1 Left ventricular noncompaction: a disorder with genotypic and phenotypic heterogeneity—a narrative review ENSG00000100811 ENSG00000175206 ENSG00000135547 ENSG00000145147 ENSG00000187266 ENSG00000164532 ENSG00000089225 ENSG00000163217 ENSG00000008083 ENSG00000142611 ENSG00000177508 ENSG00000133961 ENSG00000075213 ENSG00000178568 ENSG00000128908 ENSG00000101752 PMC4995918__F2 mf regulated mTOR signaling pathway in human DC ENSG00000163435 ENSG00000171105 ENSG00000198793 ENSG00000163914 ENSG00000169047 ENSG00000173599 ENSG00000164327 PMC12149389__F9 CMTM7 inhibits TLR4 signaling pathway via promoting Rab5 activation and alleviates acute liver injury ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000153551 PMC11992894__F9 General schematic view of enzymatic browning (EB) in apple pulp and proposed pectin-related signaling pathway ENSG00000105722 PMC8295688__F1 Impact of Diabetes and Obesity on Alveolar Type 2 (AT2)-Lipofibroblast (LIF) Interactions After COVID-19 Infection ENSG00000278718 ENSG00000162711 ENSG00000111537 ENSG00000130234 ENSG00000125538 ENSG00000184012 PMC7215355__F1 Lipid metabolic processes during HCV RNA replication, assembly, and egress ENSG00000138823 ENSG00000173599 ENSG00000110048 ENSG00000285199 ENSG00000099194 ENSG00000099246 PMC4938033__F3 Enhanced Ca2+ and ROS levels in cardiac hypertrophy ENSG00000285109 ENSG00000198626 PMC3707373__F1 Regulation of Th9-Type Pulmonary Immune Responses. A New Role for COX-2 ENSG00000166090 ENSG00000056736 PMC7076221__F8 Working model for protective effects of SIRT1 via HAS2–AS1 and NFKB ENSG00000170961 ENSG00000100473 ENSG00000096717 PMC10747773__F4 HCV-induced ROS/JNK/Itch signaling pathway promotes VSP4A polyubiquitylation, leading to enhancement of VPS4A ATPase activity, thereby upregulating the release of HCV particles ENSG00000132612 ENSG00000255112 ENSG00000078747 PMC3757331__F8 Revisiting MPF activation ENSG00000172680 ENSG00000128989 ENSG00000276876 PMC3582273__F1 CluePedia analysis example using expression data from human normal colon mucosa and colorectal tumors and in silico information ENSG00000159128 ENSG00000162630 ENSG00000156642 ENSG00000197646 ENSG00000033800 ENSG00000027697 ENSG00000196396 ENSG00000179295 ENSG00000099866 ENSG00000138115 ENSG00000111537 ENSG00000115415 ENSG00000095464 ENSG00000116030 ENSG00000002549 ENSG00000112115 ENSG00000162692 PMC3836209__F1 Metabolism of adenosine ENSG00000196839 ENSG00000291814 PMC6357837__F7 Working model of cholestasis in Pemt+/+ and Pemt–/– mice fed the HFD ENSG00000173599 ENSG00000081923 ENSG00000133027 PMC7806659__F10 The proposed hypothesis model showing that miR-148a-3p positively regulates neuronal apoptosis via activating the PI3K-AKT signaling pathway by targeting SYNJ1 ENSG00000132906 ENSG00000002330 ENSG00000198793 PMC5742211__F1 Simplified pathway of de novo sphingolipid synthesis ENSG00000063176 PMC6468702__F3 Sub-genomic flavivirus RNAs (sfRNAs) impair cellular response to viral infection ENSG00000138757 ENSG00000114127 ENSG00000121060 PMC5652078__F2 HR+, HER2– Advanced Breast Cancer and CDK4/6 Inhibitors: Mode of Action, Clinical Activity, and Safety Profiles ENSG00000135446 ENSG00000198793 ENSG00000107485 ENSG00000105810 PMC4588911__F1 IL-33/ST2 signaling pathway in mast cells ENSG00000137033 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC9448875__F7 Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway ENSG00000108702 ENSG00000108691 ENSG00000070831 ENSG00000106100 PMC9533135__F8 Nuclear Factor I-C Regulates Stemness Genes and Proliferation of Stem Cells in Various Mineralized Tissue through Epithelial-Mesenchymal Interactions in Dental Epithelial Stem Cells ENSG00000070193 ENSG00000119912 PMC6473623__F1 Autophagy-A highly conservative cascaded regulatory mechanism upholds the intracellular homeostasis of the biological system ENSG00000152348 ENSG00000188554 ENSG00000198793 ENSG00000144848 ENSG00000005893 ENSG00000070540 ENSG00000171791 ENSG00000145782 ENSG00000057663 ENSG00000136874 PMC2999341__F12 Regulatory PathRNet Only nodes that are close to P38 MAPK Signaling pathway or "S-7" are kept (distance<3) ENSG00000166278 PMC6473623__F2 Autophagy Intertwines with Different Diseases ENSG00000004975 ENSG00000177169 ENSG00000152348 ENSG00000230989 ENSG00000163568 ENSG00000274891 ENSG00000172403 ENSG00000136874 ENSG00000057663 ENSG00000102977 ENSG00000149311 ENSG00000163625 ENSG00000005893 ENSG00000144848 ENSG00000070540 ENSG00000145782 ENSG00000130254 ENSG00000104081 PMC7352608__F2 Therapeutic approaches of splicing modulation in cancer ENSG00000115524 ENSG00000063244 PMC5818153__F1 Sphingolipid metabolism in cancer signalling and therapy ENSG00000139624 ENSG00000100422 ENSG00000063176 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000173599 ENSG00000102172 ENSG00000143418 PMC2921082__F1 Adenosine monophosphate-activated protein kinase pathway in hepatic fuel metabolism ENSG00000169047 ENSG00000198793 PMC9473879__F9 Network Pharmacology and Experimental Verification Revealed the Mechanism of Yiqi Jianpi Recipe on Chronic Obstructive Pulmonary Disease ENSG00000189060 ENSG00000177606 ENSG00000168610 ENSG00000146648 PMC2921082__F4 Dual regulation of fuel metabolism and cell viability by adenosine monophosphate-activated protein kinase ENSG00000169047 ENSG00000198793 PMC5863198__F1 All roads lead to Rome: vascular inflammation ENSG00000162711 ENSG00000125538 PMC4722285__F6 Schematic model of downstream signaling after GPCR activation ENSG00000159224 ENSG00000124181 PMC3096079__F1 mTOR regulation pathway involved in hypoxia ENSG00000134086 ENSG00000198793 PMC9408823__F8 FAK-Mediated Signaling Controls Amyloid Beta Overload, Learning and Memory Deficits in a Mouse Model of Alzheimer’s Disease ENSG00000140992 ENSG00000171105 ENSG00000110395 ENSG00000115415 ENSG00000291971 ENSG00000010810 ENSG00000169047 ENSG00000281879 ENSG00000168610 ENSG00000089159 PMC8231806__F6 Dietary Curcumin Alleviated Acute Ileum Damage of Ducks (Anas platyrhynchos) Induced by AFB1 through Regulating Nrf2-ARE and NFKB Signaling Pathways ENSG00000162711 ENSG00000181019 ENSG00000173039 ENSG00000136869 ENSG00000265972 ENSG00000023909 ENSG00000079999 PMC6770582__F6 Schema of the present study ENSG00000274247 ENSG00000196371 ENSG00000197183 ENSG00000139117 PMC7551072__F1 Regulation of metabolism by B vitamins ENSG00000228716 PMC8800364__F5 Immunometabolism in biofilm infection: lessons from cancer ENSG00000112715 ENSG00000007171 PMC4125180__F8 Profiling of Luteal Transcriptome during Prostaglandin F2-Alpha Treatment in Buffalo Cows: Analysis of Signaling Pathways Associated with Luteolysis ENSG00000291971 ENSG00000171791 PMC8800364__F7 Immunometabolism in biofilm infection: lessons from cancer ENSG00000135218 ENSG00000168610 PMC7281690__F1 Role of WNT/TGFB signaling pathways in pathogenesis of cardiac fibrosis ENSG00000134982 PMC4125180__F3 Profiling of Luteal Transcriptome during Prostaglandin F2-Alpha Treatment in Buffalo Cows: Analysis of Signaling Pathways Associated with Luteolysis ENSG00000081181 ENSG00000125148 ENSG00000170458 ENSG00000143878 ENSG00000115457 ENSG00000198838 ENSG00000006327 ENSG00000164949 PMC9379405__F7 Intestinal stem cell within gut homeostasis: Focusing on its interplay with gut microbiota and the regulating pathways ENSG00000170365 ENSG00000137834 PMC7281690__F2 Crosstalk between microRNAs and WNT/TGFB signaling pathways in cardiac fibrosis ENSG00000105329 ENSG00000163914 ENSG00000168610 PMC4956099__F8 ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000134574 ENSG00000136936 PMC9379405__F5 Intestinal stem cell within gut homeostasis: Focusing on its interplay with gut microbiota and the regulating pathways ENSG00000112576 ENSG00000140564 ENSG00000069869 ENSG00000273529 ENSG00000133961 ENSG00000114315 PMC9379405__F6 Intestinal stem cell within gut homeostasis: Focusing on its interplay with gut microbiota and the regulating pathways ENSG00000087095 ENSG00000281324 ENSG00000116729 ENSG00000162337 ENSG00000134982 ENSG00000133067 ENSG00000198793 ENSG00000168036 ENSG00000177606 ENSG00000136997 ENSG00000183579 ENSG00000108375 ENSG00000083799 PMC5566524__F9 TF-FVIIa-dependent PAR2-activated signaling pathway that accounts for Beta-catenin accumulation and expression of metastatic proteins leading to enhanced migration and invasion of human breast cancer cells ENSG00000134982 ENSG00000168036 PMC7525004__F3 Genetic and pharmacological activation of Wnt/Beta-catenin promotes neurogenesis in the hippocampus of AD models ENSG00000154342 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000277641 PMC8169867__F8 EGFR-HIF1A signaling pathway in Th9 cells ENSG00000145777 ENSG00000146648 ENSG00000007171 PMC9633314__F5 Fibroblast growth factor receptor 3 overexpression mediates ALK inhibitor resistance in ALK‐rearranged non–small cell lung cancer ENSG00000143924 PMC7289676__F1 ACE2, COVID-19, and ACE Inhibitor and ARB Use during the Pandemic: The Pediatric Perspective ENSG00000175054 ENSG00000130234 PMC7102037__F2 Hyperglycemia-induced lung diseases ENSG00000163914 ENSG00000168610 PMC3974425__F5 Ezrin expression and cell survival regulation in colorectal cancer ENSG00000087245 ENSG00000291971 ENSG00000157227 ENSG00000138798 ENSG00000177606 ENSG00000168036 ENSG00000100985 ENSG00000073756 ENSG00000092820 PMC3932036__F5 Akt signaling pathway ENSG00000002330 ENSG00000105401 ENSG00000198793 PMC8771160__F8 Pyridinium-type fullerene derivative suppresses primary effusion lymphoma cell viability via the downregulation of the Wnt signaling pathway through the destabilization of Beta-catenin ENSG00000134982 ENSG00000177606 ENSG00000136997 ENSG00000196628 PMC2742090__F4 Negative feedback loops in the SHH signaling pathway driven by SHH-binding proteins ENSG00000180447 ENSG00000144857 ENSG00000164690 PMC9175009__F2 Focus on the Role of the NLRP3 Inflammasome in Multiple Sclerosis: Pathogenesis, Diagnosis, and Therapeutics ENSG00000278718 ENSG00000132109 ENSG00000162711 ENSG00000125538 ENSG00000172936 ENSG00000168040 ENSG00000159335 ENSG00000141569 PMC2709066__F1 De novo purine synthesis pathway PMC10177184__F6 Evolutionary chart of human molecular pathway Akt ENSG00000033327 ENSG00000147166 ENSG00000002330 ENSG00000291971 ENSG00000105401 ENSG00000136111 ENSG00000198793 ENSG00000167965 ENSG00000141564 ENSG00000150455 ENSG00000012048 ENSG00000177455 ENSG00000150907 ENSG00000118515 ENSG00000136869 ENSG00000102104 ENSG00000179348 ENSG00000101213 ENSG00000140443 ENSG00000185825 ENSG00000154589 ENSG00000005882 ENSG00000113070 ENSG00000060237 ENSG00000081913 ENSG00000137992 ENSG00000172936 ENSG00000100813 ENSG00000105723 PMC11027554__F2 "hit and run" mechanism posits a potential role for H ENSG00000012048 ENSG00000291971 ENSG00000168036 PMC10177184__F7 Evolutionary chart of human molecular pathway of EGFR signaling (A), Notch (B), and Hedgehog (C) pathways ENSG00000110395 ENSG00000291971 ENSG00000149269 ENSG00000138798 ENSG00000163914 ENSG00000095015 ENSG00000148429 ENSG00000169032 ENSG00000128602 ENSG00000146648 PMC5463383__F7 Proposed model showing the mechanism of action of PPARG agonists (TRG and RSG) on TGFB1-induced fibrogenic activation in human primary intestinal myofibroblasts PMC8833361__F8 Time Series Ovarian Transcriptome Analyses of the Porcine Estrous Cycle Reveals Gene Expression Changes during Steroid Metabolism and Corpus Luteum Development ENSG00000151657 ENSG00000117425 ENSG00000164161 ENSG00000141480 ENSG00000171791 ENSG00000128602 PMC10177184__F9 Evolutionary chart of human molecular pathway of WNT signaling ENSG00000156076 ENSG00000137673 ENSG00000162337 ENSG00000134982 PMC3075371__F1 Local control of Beta-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca2+-transient ENSG00000148798 PMC3407375__F3 MicroRNA Circuits in Transforming Growth FactorB actions and Diabetic Nephropathy ENSG00000169554 ENSG00000065978 PMC6753331__F1 MiR-155 is expressed in plasma (P), monocytes, fibroblast-like synoviocytes (RASF) and synovial fluid monocytes (SFCD14*C) of patients with RA/JIA ENSG00000115415 ENSG00000136869 ENSG00000120868 ENSG00000175104 ENSG00000184216 PMC7797856__F5 Six core genes (COMP, SPP1, COL1A1, IL6, VWF, TEK) were significantly enriched in the PI3K-Akt signaling pathway ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000002330 ENSG00000105401 ENSG00000186716 ENSG00000198793 ENSG00000169047 ENSG00000152430 PMC8375323__F9 TIMM17A Regulatory Network Contributing to Breast Cancer ENSG00000135451 ENSG00000284770 ENSG00000073111 ENSG00000145386 ENSG00000166851 ENSG00000069275 ENSG00000128050 ENSG00000072571 ENSG00000137807 ENSG00000138778 ENSG00000089685 ENSG00000282899 ENSG00000277909 ENSG00000164109 ENSG00000131747 ENSG00000101057 ENSG00000167900 ENSG00000126787 ENSG00000117399 ENSG00000276043 ENSG00000094804 ENSG00000117650 ENSG00000134057 ENSG00000143476 ENSG00000109805 ENSG00000171848 ENSG00000197299 ENSG00000149554 ENSG00000069248 PMC3466334__F3 Genetically-defined metabolic reprogramming in cancer ENSG00000079999 PMC7227004__F1 YAP/TAZ activity is tightly regulated—Hippo signaling and beyond ENSG00000020633 ENSG00000150457 ENSG00000067955 ENSG00000146648 ENSG00000131023 ENSG00000178568 PMC3466334__F1 Genetically-defined metabolic reprogramming in cancer ENSG00000122966 ENSG00000092621 ENSG00000172005 PMC3974514__F1 Metabolic pathway of azathioprine/mercaptopurine metabolism ENSG00000137364 PMC8375323__F4 TIMM17A Regulatory Network Contributing to Breast Cancer ENSG00000277649 ENSG00000164284 ENSG00000134375 ENSG00000292215 PMC6723645__F1 Pathway inhibition by targeted agents and their effects on cell proliferation, apoptosis, metastasis and angiogenesis ENSG00000177606 ENSG00000136997 ENSG00000115904 PMC2871922__F4 Regulation of spermatogenesis processes by non-classical testosterone signalling ENSG00000146648 PMC2574672__F2 Iron–sulfur (Fe-S) cluster biogenesis in eukaryotes ENSG00000103274 ENSG00000182511 ENSG00000100209 ENSG00000161513 ENSG00000144021 ENSG00000136003 ENSG00000141562 ENSG00000095906 PMC4530367__F1 Alternative pathway of the complement system.The activation of the alternative pathway of the complement system depends on spontaneous hydrolysis of complement factor 3 (C3) in plasma leading to the formation of C3(H2O) ENSG00000039537 ENSG00000113600 PMC5633564__F1 Folic acid and the one carbon cycle (1-CC) PMC6900372__F4 The results of pathway enrichment analysis ENSG00000292348 ENSG00000169896 ENSG00000166086 ENSG00000154721 ENSG00000115232 ENSG00000135605 ENSG00000121966 ENSG00000154096 PMC5363986__F1 The Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt ENSG00000134982 ENSG00000114315 PMC7767525__F1 Summary of the activity of FANC proteins in the FA/BRCA pathway ENSG00000131944 ENSG00000012048 ENSG00000175054 ENSG00000188827 ENSG00000187790 ENSG00000168411 ENSG00000162607 PMC7767525__F2 Major mechanisms of double-strand break repair ENSG00000143799 ENSG00000144554 ENSG00000051180 ENSG00000183624 ENSG00000177084 ENSG00000122783 PMC9233184__F1 Complex relationship between integrins and oncolytic herpes Simplex Virus 1 in high-grade glioma therapeutics ENSG00000187605 ENSG00000133937 ENSG00000105329 ENSG00000291971 ENSG00000168036 ENSG00000168610 ENSG00000146648 PMC2940983__F1 Histone GH2AX and Poly(ADP ribose) as Clinical Pharmacodynamic Biomarkers ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 PMC8015888__F8 Immune detection, inflammatory signaling and intracellular fate of MVs produced by Gram‐positive bacteria ENSG00000108691 ENSG00000239732 ENSG00000167207 PMC4598198__F2 effect of lipoxins on cytoplasmic signaling cascades and transcription factors.Notes: Lipoxin binds to its G protein-coupled receptor ALX/Formyl peptidyl receptor triggering a wide array of cytoplasmic signaling cascades ENSG00000198793 ENSG00000138386 ENSG00000005381 PMC11872610__F1 Design and preparation of Qu-CDs for the treatment of burn wound healing ENSG00000170365 ENSG00000170558 ENSG00000118520 ENSG00000283060 ENSG00000125968 ENSG00000172201 PMC5862596__F1 Quantitative mass spectrometry analysis reveals a panel of nine proteins as diagnostic markers for colon adenocarcinomas ENSG00000146648 ENSG00000026103 PMC9287179__F8 Mechanism of the ANKFN1 gene in HCC ENSG00000135446 ENSG00000132646 ENSG00000105810 PMC10537516__F1 IL-15 and N-803 for HIV Cure Approaches ENSG00000105639 ENSG00000196396 PMC2836046__F7 Proposal of the regulatory loop of miR-24, miR-34a, and HNF4A in bile acid synthesis ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC8997790__F3 Vitamin D and Hypoxia: Points of Interplay in Cancer ENSG00000168209 ENSG00000173846 PMC5520163__F1 How the MyD88 pathway triggers the ubiquitylation of IRAK1 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC3850498__F1 Inhibition of the mevalonate pathway to override chemoresistance and promote the immunogenic demise of cancer cells ENSG00000150782 ENSG00000197429 ENSG00000184207 PMC12037491__F7 Possible mechanism of central tolerance of thymic T cells induced by H ENSG00000291603 ENSG00000134982 ENSG00000175104 ENSG00000086065 PMC6785648__F1 Important factors involved in the pathogenicity of septic shock caused by LPS from gram-negative bacteria ENSG00000130164 ENSG00000100979 ENSG00000189403 ENSG00000136869 PMC8569819__F8 TNF signaling Kegg Pathway report for up-regulated DEGS caused by WYE (Low) 15 μg/ml vs. untreated controls after meeting selection criteria; -2+2 fold change, p-Value <0.05 and FDR p-Value <0.05. Up-regulated DEGS are demarcated by a red star ENSG00000078747 ENSG00000079432 ENSG00000168040 PMC3050939__F3 Host Defense against Viral Infection Involves Interferon Mediated Down-Regulation of Sterol Biosynthesis ENSG00000160752 ENSG00000067064 ENSG00000110921 ENSG00000112972 ENSG00000164219 ENSG00000152904 ENSG00000172893 ENSG00000197429 ENSG00000113161 ENSG00000167508 PMC3328748__F11 The molecular players involved in angiogenesis signalling mediated by the interaction of VEGF-A with VEGFR-2 ENSG00000169291 PMC6461577__F8 Fludarabine Improves NDV-Mediated Oncolytic Viro-immunotherapyOn the one hand, the viral RNA activates the cytoplasmic RIG-I signaling pathway in the host cells to produce type I IFNs or other antiviral molecules ENSG00000088888 ENSG00000115415 ENSG00000168610 ENSG00000276561 ENSG00000142166 PMC7460249__F1 Metabolic reprogramming in cancer ENSG00000125166 ENSG00000135218 ENSG00000136997 ENSG00000026103 PMC2737689__F2 Multiple isoforms catalyze each step in the glycerol-3-phosphate pathway of TAG synthesis ENSG00000151726 ENSG00000173599 ENSG00000158669 ENSG00000285482 ENSG00000198670 ENSG00000026652 ENSG00000160216 ENSG00000186281 ENSG00000062282 PMC2889025__F2 P53 stabilization ENSG00000149311 ENSG00000175054 ENSG00000136997 PMC2907396__F3 Genome-Wide Expression Profiling Deciphers Host Responses Altered during Dengue Shock Syndrome and Reveals the Role of Innate Immunity in Severe Dengue ENSG00000110395 ENSG00000213658 ENSG00000010810 ENSG00000177606 ENSG00000173039 PMC8646611__F5 Rapid Detection and Inhibition of SARS‐CoV‐2‐Spike Mutation‐Mediated Microthrombosis ENSG00000113905 ENSG00000142192 ENSG00000108691 ENSG00000140564 ENSG00000005961 ENSG00000124491 ENSG00000136869 ENSG00000185591 ENSG00000171560 ENSG00000121966 ENSG00000163631 PMC2907574__F4 Inhibition of host signalling pathways by VACV members of A46 and related families ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC2889025__F1 Response of p53 to DSBs generated by ionizing radiation ENSG00000149311 ENSG00000175054 ENSG00000123374 ENSG00000093009 PMC5825991__F2 Targeting pattern-recognition receptor signaling in human intestinal inflammation ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000104237 ENSG00000134070 PMC3983064__F9 Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation ENSG00000239732 ENSG00000167207 ENSG00000187796 ENSG00000125538 ENSG00000172936 PMC4679489__F2 Critical role of toll-like receptors - From microbial recognition to autoimmunity: A comprehensive review ENSG00000174125 ENSG00000132478 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172005 ENSG00000157625 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC2889025__F4 Crosstalk between the PI3K/AKT pathway and p53 activation: Potential stratagies for combined radiosensitization ENSG00000149311 ENSG00000175054 PMC4235299__F1 Genes for which a correlation with Wnt/Beta-catenin signaling was indicated by MetaCore pathway analysis ENSG00000153721 ENSG00000134982 ENSG00000184634 PMC4243082__F1 Regulatory network of cell-fate decision upon DNA damage involving (A) the G1/S checkpoint arrest network and (B) the senescence regulatory pathway ENSG00000149311 ENSG00000175054 ENSG00000149554 ENSG00000139687 ENSG00000183765 PMC9516659__F2 Dissecting novel mechanisms of hepatitis B virus related hepatocellular carcinoma using meta-analysis of public data ENSG00000288445 ENSG00000009724 ENSG00000115902 ENSG00000115163 ENSG00000160339 ENSG00000273991 ENSG00000123219 ENSG00000100162 ENSG00000124479 ENSG00000203760 ENSG00000120334 ENSG00000165471 ENSG00000060762 PMC9516659__F3 Dissecting novel mechanisms of hepatitis B virus related hepatocellular carcinoma using meta-analysis of public data ENSG00000117724 ENSG00000065328 ENSG00000117650 ENSG00000156970 ENSG00000150907 ENSG00000131747 ENSG00000196642 ENSG00000205250 ENSG00000073111 PMC9516659__F4 Dissecting novel mechanisms of hepatitis B virus related hepatocellular carcinoma using meta-analysis of public data ENSG00000174156 ENSG00000274619 ENSG00000151365 ENSG00000099194 ENSG00000178726 ENSG00000125968 PMC4905575__F3 PP2A positively and negatively regulates the Wnt signaling pathway ENSG00000134982 ENSG00000168036 PMC4905575__F4 PP2A negatively regulates the mTOR signaling pathway ENSG00000177169 ENSG00000134982 ENSG00000106070 ENSG00000198793 ENSG00000169047 ENSG00000145979 ENSG00000164327 ENSG00000167965 PMC7665448__F2 SARS-CoV-2 infects the host through angiotensin-converting enzyme (ACE) 2 receptors which are elevated in inflammatory conditions ENSG00000137033 ENSG00000130234 ENSG00000132693 PMC7591896__F1A Transcriptome analysis of chicken intraepithelial lymphocyte natural killer cells infected with very virulent infectious bursal disease virus ENSG00000099985 ENSG00000156574 ENSG00000054967 ENSG00000104081 PMC6565995__F2 Gene coexpression network for trans-1,4-polyisoprene biosynthesis involving mevalonate and methylerythritol phosphate pathways in Eucommia ulmoides Oliver ENSG00000160752 ENSG00000110921 ENSG00000112972 ENSG00000113161 ENSG00000120437 ENSG00000167508 ENSG00000075239 PMC4465592__F1 Attacking the Multi-tiered Proteolytic Pathology of COPD: New Insights from Basic and Translational Studies ENSG00000100985 PMC3742039__F3 Gene expression in keratinocytes related to IL-1 signaling ENSG00000115008 ENSG00000128342 ENSG00000146648 ENSG00000122194 ENSG00000179295 PMC8807458__F3 Mechano-regulated cell–cell signaling in the context of cardiovascular tissue engineering PMC3382313__F1 The role of Notch ligands in our models ENSG00000239732 ENSG00000105397 ENSG00000128917 ENSG00000115415 ENSG00000172936 PMC7346118__F3 Pathways involved in polymyxin-induced nephrotoxicity and the potential nephro-protective mechanism of curcumin ENSG00000086991 ENSG00000168040 ENSG00000026103 PMC9534868__F2 Activation of the canonical Wnt signaling pathway ENSG00000281324 ENSG00000134982 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC5777756__F8 Insufficient microwave ablation-induced promotion of distant metastasis is suppressed by Beta-catenin pathway inhibition in breast cancer ENSG00000138795 ENSG00000170558 ENSG00000168036 PMC3676786__F1 Representative anti-angiogenic drugs and their targets in the angiogenic pathway ENSG00000122025 ENSG00000157404 ENSG00000112715 PMC3372917__F1 PTPN11-Associated Mutations in the Heart: Has LEOPARD changed its RASpots? ENSG00000157764 ENSG00000110395 ENSG00000198793 ENSG00000115904 ENSG00000166068 ENSG00000108061 ENSG00000196712 ENSG00000062485 PMC4223355__F9 Model of PLB1 transcriptional activation upon loss of Ypk1 or upon disruption to sphingolipid biosynthesis through treatment with myriocin ENSG00000228278 ENSG00000173599 ENSG00000229314 PMC2570214__F8 Anti-EGFR Antibody Efficiently and Specifically Inhibits Human TSC2−/− Smooth Muscle Cell Proliferation. Possible Treatment Options for TSC and LAM ENSG00000138798 PMC5472757__F9 DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity ENSG00000164430 PMC5405080__F9 Functional p53 control of cell growth and oxidative metabolism ENSG00000198793 ENSG00000078237 PMC8561620__F5 Regulatory effect between HMGA2 and the Wnt/Beta-catenin signaling pathway in the carcinogenesis of sporadic colorectal tubular adenoma ENSG00000281324 ENSG00000162337 ENSG00000135446 ENSG00000168036 PMC9583502__F2 Review on the role of cyclin dependent kinases in cancers ENSG00000094631 ENSG00000087245 ENSG00000138639 ENSG00000123374 ENSG00000143499 ENSG00000168610 PMC6012981__F5 Metabolic Regulation of Adipose Tissue Macrophage Function in Obesity and Diabetes ENSG00000140968 ENSG00000184916 PMC5462521__F1 YAP protein interaction, activation, and inactivation within the canonical Hippo Pathway ENSG00000186575 ENSG00000131023 PMC9549360__F4 Regulation and potential roles of m6A modifications in early embryonic development and immune tolerance at the maternal-fetal interface ENSG00000168209 ENSG00000115415 ENSG00000149658 ENSG00000198492 ENSG00000198793 ENSG00000073792 ENSG00000136869 ENSG00000106100 ENSG00000165819 PMC4123224__F6 Mechanism and implications of CXCR4-mediated integrin activation by Porphyromonas gingivalis ENSG00000174125 ENSG00000172936 ENSG00000121966 PMC7290655__F6 In PI3K-Akt signaling pathway (KEGG ID: hsa04151), various PKs and PPCPs are involved in translating the extracellular stimuli into phosphorylation signals and propagating these signals into downstream pathways ENSG00000171105 ENSG00000002330 ENSG00000170027 ENSG00000175793 ENSG00000169047 ENSG00000136111 ENSG00000077782 ENSG00000146648 ENSG00000160691 PMC11758792__F1 Lung TME chip operation principles ENSG00000111537 PMC5429325__F1 Action of branch‐chained amino acids (BCAAs) ENSG00000198793 ENSG00000115138 ENSG00000096717 PMC4002662__F2 Chemoprevention of Head and Neck Squamous Cell Carcinoma through Inhibition of NFKB Signaling ENSG00000082512 ENSG00000056558 ENSG00000173039 ENSG00000175104 ENSG00000127191 ENSG00000146648 PMC4002662__F1 Chemoprevention of Head and Neck Squamous Cell Carcinoma through Inhibition of NFKB Signaling ENSG00000104856 ENSG00000082512 ENSG00000198793 ENSG00000056558 ENSG00000173039 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000146648 PMC6533679__F12 Schematic representation of the underlying mechanism of miR-137 in CC ENSG00000170558 PMC8650160__F2 RAD52: Paradigm of Synthetic Lethality and New Developments ENSG00000144554 ENSG00000080345 ENSG00000188827 ENSG00000176208 ENSG00000132646 ENSG00000051180 ENSG00000138375 PMC4939482__F3 Role of the ACE2/Angiotensin 1–7 axis of the Renin-Angiotensin System in Heart Failure ENSG00000175054 ENSG00000087245 ENSG00000130234 ENSG00000100985 PMC8773762__F2 Adipose Triglyceride Lipase in Hepatic Physiology and Pathophysiology ENSG00000185591 ENSG00000096717 PMC4388523__F4 Increase of microRNA-210, Decrease of Raptor Gene Expression and Alteration of Mammalian Target of Rapamycin Regulated Proteins following Mithramycin Treatment of Human Erythroid Cells ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000130656 ENSG00000158578 ENSG00000256269 ENSG00000188690 PMC4939482__F1 Role of the ACE2/Angiotensin 1–7 axis of the Renin-Angiotensin System in Heart Failure ENSG00000130234 PMC4977324__F2 Influence diagram of contains partial prior biological knowledge and epigenetic information in the form of methylation and histone modification ENSG00000138795 ENSG00000197380 ENSG00000155011 ENSG00000104371 ENSG00000136997 ENSG00000026508 ENSG00000104332 ENSG00000196628 ENSG00000164488 PMC9616080__F2 Epithelial cell alarmin cytokines: Frontline mediators of the asthma inflammatory response ENSG00000115415 ENSG00000145777 ENSG00000168610 PMC9616080__F3 Epithelial cell alarmin cytokines: Frontline mediators of the asthma inflammatory response ENSG00000183283 ENSG00000056736 ENSG00000175104 ENSG00000076604 PMC4977324__F4 Influence diagram of is a naive Bayes model that contains minimal prior biological knowledge ENSG00000138795 ENSG00000197380 ENSG00000155011 ENSG00000104371 ENSG00000136997 ENSG00000026508 ENSG00000106483 ENSG00000104332 ENSG00000165617 ENSG00000164488 PMC9616080__F4 Epithelial cell alarmin cytokines: Frontline mediators of the asthma inflammatory response ENSG00000115602 ENSG00000137033 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC8551477__F4 Insulin action at a molecular level – 100 years of progress ENSG00000110395 ENSG00000042832 ENSG00000288269 PMC8551477__F5 Insulin action at a molecular level – 100 years of progress ENSG00000124102 ENSG00000178602 ENSG00000171105 ENSG00000150907 ENSG00000139515 ENSG00000160741 PMC2937064__F1 Leptin, IGFBP3, and rapamycin suppress the IGF-1 signaling pathway to preserve naïve T cells and promote longevity ENSG00000139193 ENSG00000198793 ENSG00000168610 PMC7102884__F1 Exhibits the involvement of transduction pathway in AML ENSG00000107562 ENSG00000198793 ENSG00000121966 PMC2937064__F3 CD28 signaling pathway in T cells is equivalent to the IGF-1 pathway in the whole organism ENSG00000150907 ENSG00000140443 PMC8750552__F7 Ginsenoside Rg3 Attenuates TNF-Alpha-Induced Damage in Chondrocytes through Regulating SIRT1-Mediated Anti-Apoptotic and Anti-Inflammatory Mechanisms ENSG00000171791 ENSG00000096717 ENSG00000142082 PMC2937064__F4 Reactive oxygen species, UV light or other genotoxic stresses, that induce DNA damage, principally, double-stranded breaks, is detected by the MRE11-RAD50-NBS1 complex, which in turn activates ATM ENSG00000149311 ENSG00000198793 PMC6375051__F2 Mitophagy links oxidative stress conditions and neurodegenerative diseases ENSG00000158828 PMC5297661__F6 Protein association networks ENSG00000109332 ENSG00000077721 ENSG00000117298 ENSG00000170606 ENSG00000170142 ENSG00000170348 ENSG00000168615 ENSG00000182247 ENSG00000143801 ENSG00000126803 ENSG00000072401 ENSG00000205155 ENSG00000188130 ENSG00000119912 PMC8491233__F2 Mitochondria as a target in cancer treatment ENSG00000146648 PMC11170970__F6 SH alleviates DSS‐induced colitis via the “SH‐gut microbiota‐5HIAA‐AhR axis ENSG00000125538 ENSG00000106546 PMC5584301__F2 SETBP1 dysregulation in congenital disorders and myeloid neoplasms ENSG00000152217 PMC7129598__F1 General overview of disease progression ENSG00000125538 ENSG00000145321 ENSG00000026103 PMC3882141__F1 Regulatory Networks and Complex Interactions between the Insulin and Angiotensin II Signalling Systems: Models and Implications for Hypertension and Diabetes ENSG00000005882 ENSG00000198793 PMC6213971__F3 Regulation of PTPIP51 in melanoma ENSG00000122025 ENSG00000157764 PMC8530550__F1 Artificial immune synapse with an introduced DNA-based mechanics-controlling module ENSG00000291603 ENSG00000134982 PMC8194072__F1 Pleiotropic Roles of CXCR4 in Wound Repair and Regeneration ENSG00000138798 ENSG00000198793 ENSG00000163914 ENSG00000121966 PMC7484613__F1 Ageing and atherosclerosis: vascular intrinsic and extrinsic factors and potential role of IL-6 ENSG00000125538 PMC8194072__F3 Pleiotropic Roles of CXCR4 in Wound Repair and Regeneration ENSG00000178860 ENSG00000128928 ENSG00000121966 PMC2724029__F4 Signaling networks upregulated in migrating neuroblasts ENSG00000112290 ENSG00000135643 ENSG00000119878 ENSG00000103657 ENSG00000038427 PMC9255247__F2 Prostate cancer stem-like cells in the development of antiandrogen resistance ENSG00000134982 ENSG00000173039 ENSG00000168036 ENSG00000128602 PMC2724029__F5 Signaling networks upregulated in migrating neuroblasts ENSG00000038382 ENSG00000073803 ENSG00000082397 ENSG00000160145 ENSG00000102606 ENSG00000126217 ENSG00000109466 ENSG00000150764 ENSG00000065559 ENSG00000132478 ENSG00000160293 PMC12045949__F1 Molecular Mechanisms Underlying ALKBH5-Mediated Regulation of Hepatic Glucose and Lipid Metabolism ENSG00000288269 ENSG00000198793 ENSG00000169710 ENSG00000091542 ENSG00000146648 PMC8427323__F1 Identification of novel inhibitory metabolites and impact verification on growth and protein synthesis in mammalian cells ENSG00000179091 ENSG00000172005 ENSG00000154059 PMC9019265__F1 Statins and endocrine resistance in breast cancer ENSG00000041353 ENSG00000198793 ENSG00000163914 PMC6854496__F1 RIG-I-like receptor (RLR) activation by various RNAs during DNA virus infection ENSG00000183735 ENSG00000088888 ENSG00000291483 ENSG00000112110 ENSG00000276561 PMC5511499__F4 How is the Brain Renin-Angiotensin System Regulated? ENSG00000162337 ENSG00000168036 PMC8387362__F1 Study workflow ENSG00000149311 ENSG00000012048 ENSG00000104884 ENSG00000083093 ENSG00000137948 ENSG00000139618 PMC3613369__F3 Intra-Tumoral Heterogeneity in Metastatic Potential and Survival Signaling between Iso-Clonal HCT116 and HCT116b Human Colon Carcinoma Cell Lines ENSG00000082397 ENSG00000135218 ENSG00000204103 ENSG00000125384 ENSG00000158270 ENSG00000102409 ENSG00000117152 ENSG00000100842 ENSG00000128510 ENSG00000118971 PMC9110257__F9 LARS2 Regulates Apoptosis via ROS-Mediated Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Ovarian Granulosa Cells ENSG00000116688 ENSG00000011376 ENSG00000164305 PMC1592599__F1 TNFA signaling pathway leading to apoptosis or proliferation of the cells ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC4394389__F8 Nanotopographical Surfaces for Stem Cell Fate Control: Engineering Mechanobiology from the Bottom ENSG00000172005 PMC9247951__F2 Neuropilin-2-mediated signaling axis in cancer progression and therapy resistance ENSG00000019991 ENSG00000156076 ENSG00000118785 ENSG00000291971 ENSG00000117707 ENSG00000118257 ENSG00000179348 PMC6952997__F8 Influence of ethylene on amount of compounds and expression of genes in lipid pathway in peach ENSG00000173599 ENSG00000198670 ENSG00000184207 ENSG00000133027 PMC5746035__F3 Oncogenic regulation of glucose flux into PPP ENSG00000180210 ENSG00000105810 ENSG00000078237 PMC7564365__F6 Pilot Study on MicroRNA Profile in Tear Fluid to Predict Response to Anti-VEGF Treatments for Diabetic Macular Edema ENSG00000170365 ENSG00000002330 ENSG00000108557 PMC5746035__F1 The glycolysis and pentose phosphate pathways (PPP) are tightly connected ENSG00000180210 ENSG00000078237 PMC6152083__F10 Part of the PPAR signal pathway ENSG00000135218 ENSG00000165269 ENSG00000173391 ENSG00000113790 PMC4709516__F3 The Dendrobium catenatum Lindl. genome sequence provides insights into polysaccharide synthase, floral development and adaptive evolution ENSG00000069482 ENSG00000111816 PMC8982327__F5 Targeting transforming growth factor‐B signalling for cancer prevention and intervention: Recent advances in developing small molecules of natural origin PMC5818366__F1 “cross-talk” between liver and peripheral organs in the pathogenesis of NAFLD ENSG00000100344 ENSG00000115138 PMC8982327__F1 Targeting transforming growth factor‐B signalling for cancer prevention and intervention: Recent advances in developing small molecules of natural origin ENSG00000198793 PMC5998384__F3 Metabolic PathwaysCell-cycle effect on the stability of protein components of the pentose phosphate pathway (PPP) PMC11740669__F1 Autophagy negatively regulates pyroptosis pathway ENSG00000184979 ENSG00000278718 ENSG00000177169 ENSG00000162711 ENSG00000197530 ENSG00000144118 ENSG00000198793 ENSG00000136536 ENSG00000237693 ENSG00000168961 PMC9247951__F3 Neuropilin-2-mediated signaling axis in cancer progression and therapy resistance ENSG00000291971 ENSG00000168036 ENSG00000150093 ENSG00000171791 ENSG00000112715 ENSG00000164305 ENSG00000010319 ENSG00000133983 ENSG00000118257 ENSG00000144227 ENSG00000144746 ENSG00000139641 ENSG00000130827 ENSG00000114554 ENSG00000254221 ENSG00000127022 ENSG00000004399 ENSG00000168610 ENSG00000170381 ENSG00000075223 ENSG00000164050 ENSG00000135424 ENSG00000134121 ENSG00000146648 ENSG00000150630 PMC3823093__F4 Network analysis of proteomics using IPA ENSG00000133020 ENSG00000171403 ENSG00000006788 ENSG00000124610 ENSG00000153037 ENSG00000197951 ENSG00000213619 ENSG00000147324 ENSG00000136997 ENSG00000119608 ENSG00000184076 ENSG00000083720 ENSG00000163638 ENSG00000091140 PMC6068015__F1 Lymphoma immune evasion mechanisms ENSG00000116815 ENSG00000089692 ENSG00000198053 ENSG00000276051 ENSG00000026103 PMC3520045__F4 Summary diagram of Nrf2 and HIF1 stimulation in presence of oxidative stress ENSG00000134086 ENSG00000079999 PMC11740669__F6 LMP with STAT3 signaling pathway promotes pyroptosis and ferroptosis ENSG00000278718 ENSG00000162711 ENSG00000164430 ENSG00000168610 PMC6731416__F9 Proposed model for the roles of Wnt/Beta-catenin signaling regulated by quercetin in protection of BBB breakdown ENSG00000138795 ENSG00000168036 PMC11740669__F2 Ferritinophagy regulatory network influences ferroptosis sensitivity ENSG00000188786 ENSG00000149311 ENSG00000118564 ENSG00000198793 ENSG00000167996 ENSG00000112561 ENSG00000118640 ENSG00000079999 PMC11740669__F3 Mitophagy resists two forms of cell death ENSG00000278718 ENSG00000177169 ENSG00000162711 ENSG00000167468 ENSG00000198793 ENSG00000158828 ENSG00000112561 ENSG00000069509 PMC11740669__F5 Innate immune system regulates two types of ICD through autophagy ENSG00000278718 ENSG00000162711 ENSG00000183735 ENSG00000164430 ENSG00000167468 ENSG00000172936 ENSG00000136869 ENSG00000131023 PMC6326181__F7 Integrative Modeling of Cancer-Type-Specific Hippo Regulatory Networks ENSG00000113645 ENSG00000101109 ENSG00000149930 ENSG00000030419 ENSG00000160551 ENSG00000134982 ENSG00000135090 ENSG00000171940 ENSG00000197905 ENSG00000139926 ENSG00000114978 ENSG00000007866 ENSG00000079432 ENSG00000150457 ENSG00000131023 ENSG00000074219 ENSG00000117713 ENSG00000149311 ENSG00000186575 ENSG00000108375 ENSG00000139687 ENSG00000146648 ENSG00000140443 PMC3823158__F1 Canonical NFKB signalling pathway ENSG00000102871 ENSG00000127191 PMC5209488__F6 Summary of the mechanism of Dicer regulation in osteogenesis ENSG00000134982 ENSG00000168036 PMC2493210__F1 Schematic diagrams of small intestine mucosa in normal and infected intestines ENSG00000167207 ENSG00000136869 ENSG00000101425 PMC7848146__F2 Signaling pathway and mechanism related to lung cancer driver gene in brain metastasis ENSG00000198793 ENSG00000168036 PMC1797319__F1 Shewanella oneidensis MR-1 anaerobic carbon metabolism pathway ENSG00000122966 ENSG00000172005 PMC6770221__F6 Mechanism of optimal therapeutic drugs in each subtype of breast cancer ENSG00000157764 ENSG00000128052 ENSG00000177606 ENSG00000281879 PMC5381176__F8 MiR-93 activates the PI3K/Akt pathway by targeting LKB1/PTEN/p21 ENSG00000198793 ENSG00000146648 PMC3394417__F1 Sample gene regulatory network ENSG00000017797 PMC5203625__F3 Selected metabolic pathways of the putative novel SAOB unFirm02_FrBGR cluster 2 ENSG00000182511 ENSG00000166278 PMC7369933__F3 One-carbon metabolism, DNA/histone methylation, and drug interaction ENSG00000100714 ENSG00000205221 PMC7493015__F7 Epithelial repair mediated by LXA4 in bronchial epithelium ENSG00000244165 ENSG00000171049 ENSG00000110218 PMC7493015__F3 Arachidonic acid (AA) metabolome and abnormal class switching in CF ENSG00000166278 PMC8849533__F8 Working model of the role of CNTN1 in the regulation of MAVS-mediated signaling and influenza A virus replication ENSG00000183735 ENSG00000088888 ENSG00000018236 ENSG00000155313 PMC7493015__F5 Ion transport regulation by LXA4 and RvD1 enabling the restoration of ASL height in CF human bronchial epithelial cells ENSG00000244165 ENSG00000171049 ENSG00000110218 PMC6102449__F6 Working pathway for Er-Miao-Fang inhibiting inflammation and blocking hepatic gluconeogenesis ENSG00000125538 PMC2899872__F1 Sequence Comparison Suggests a Role for TTL in Allantoin Biosynthesis.(A) Alignment of TTL with Urad and Urah protein from zebrafish ENSG00000183463 ENSG00000114999 PMC9367608__F1 Metabolic Pathways as a Novel Landscape in Pancreatic Ductal Adenocarcinoma ENSG00000125166 ENSG00000169710 ENSG00000159399 PMC3182268__F1 Apoptotic pathway to cell death from the perspective of the Bcl-2 family of proteins.1, The intrinsic pathway is initiated by various signals, principally extracellular stimuli ENSG00000002330 ENSG00000026103 PMC8830542__F1 Nevi, dysplastic nevi, and melanoma: Molecular and immune mechanisms involving the progression ENSG00000157764 ENSG00000115138 PMC5562214__F7 Cardioprotective effects of macitentan ENSG00000135218 ENSG00000177238 ENSG00000156885 ENSG00000103150 ENSG00000168036 ENSG00000011376 ENSG00000124212 ENSG00000173546 ENSG00000283100 ENSG00000158125 ENSG00000157500 ENSG00000115415 ENSG00000005421 ENSG00000117601 ENSG00000154415 PMC6391848__F4 Enrichment analysis of differentially expressed mRNAs ENSG00000115718 ENSG00000139687 PMC8492658__F1 Cardiac molecular setting of metabolic syndrome in pigs reveals disease susceptibility and suggests mechanisms that exacerbate COVID-19 outcomes in patients ENSG00000125384 ENSG00000124212 ENSG00000101333 ENSG00000158125 PMC8492658__F6 Cardiac molecular setting of metabolic syndrome in pigs reveals disease susceptibility and suggests mechanisms that exacerbate COVID-19 outcomes in patients ENSG00000130234 ENSG00000171388 PMC9147606__F2 Endothelial Dysfunction Induced by Extracellular Neutrophil Traps Plays Important Role in the Occurrence and Treatment of Extracellular Neutrophil Traps-Related Disease ENSG00000162711 ENSG00000239732 ENSG00000125538 ENSG00000136869 ENSG00000162924 ENSG00000005381 PMC4716080__F1 Wnt-Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000026508 ENSG00000168036 PMC3789714__F1 Feeding Uninvited Guests: mTOR and AMPK Set the Table for Intracellular Pathogens ENSG00000177169 ENSG00000198793 PMC5477782__F8 The haptoglobin beta subunit sequesters HMGB1 toxicity in sterile and infectious inflammation ENSG00000177575 ENSG00000189403 PMC6084451__F1 Host-Intrinsic Interferon Status in Infection and Immunity ENSG00000213928 ENSG00000088888 ENSG00000115415 PMC5825896__F9 Schema of the anti-HIV mechanism of toll-like receptor 3 (TLR3) signaling of intestinal epithelial cells (IECs) ENSG00000187608 ENSG00000276561 ENSG00000135517 ENSG00000164342 PMC9147606__F3 Endothelial Dysfunction Induced by Extracellular Neutrophil Traps Plays Important Role in the Occurrence and Treatment of Extracellular Neutrophil Traps-Related Disease ENSG00000168036 ENSG00000005381 PMC2648516__F1 SKN-1 and the Wnt effector TCF/POP-1 reveals differences in endomesoderm specification ENSG00000204070 ENSG00000184634 ENSG00000125686 PMC4052347__F5 PPI network and signaling pathway analysis ENSG00000282905 ENSG00000005339 ENSG00000171720 ENSG00000147099 ENSG00000050748 ENSG00000261236 ENSG00000061273 ENSG00000177606 ENSG00000100429 ENSG00000164305 ENSG00000131196 ENSG00000132170 PMC6056651__F7 Pan-Cancer Analysis Reveals the Functional Importance of Protein Lysine Modification in Cancer Development ENSG00000145996 ENSG00000112499 ENSG00000127511 ENSG00000163738 ENSG00000130935 ENSG00000174197 ENSG00000137033 ENSG00000152520 ENSG00000130638 ENSG00000100888 ENSG00000164107 ENSG00000107485 ENSG00000136848 ENSG00000131480 ENSG00000162365 ENSG00000164597 ENSG00000173230 ENSG00000132694 ENSG00000125740 ENSG00000088826 ENSG00000173120 ENSG00000164935 ENSG00000160746 ENSG00000169136 ENSG00000169744 ENSG00000020633 ENSG00000132153 ENSG00000123415 ENSG00000073792 ENSG00000215301 ENSG00000118058 ENSG00000125755 ENSG00000116044 ENSG00000172239 ENSG00000086232 ENSG00000111058 ENSG00000128272 ENSG00000172497 ENSG00000075891 ENSG00000107611 ENSG00000131196 ENSG00000168237 ENSG00000160075 ENSG00000163814 ENSG00000170802 ENSG00000109111 ENSG00000159216 ENSG00000136371 ENSG00000025293 ENSG00000183549 ENSG00000185022 ENSG00000164904 ENSG00000122257 ENSG00000119640 ENSG00000153391 ENSG00000129691 ENSG00000151611 ENSG00000065268 ENSG00000132763 ENSG00000119771 ENSG00000001497 ENSG00000115421 ENSG00000091879 ENSG00000153531 ENSG00000157212 ENSG00000137731 ENSG00000163412 ENSG00000164089 ENSG00000172508 ENSG00000167110 ENSG00000109118 ENSG00000005302 ENSG00000283068 ENSG00000128607 ENSG00000101104 ENSG00000134827 ENSG00000188739 ENSG00000120094 ENSG00000054267 ENSG00000258315 ENSG00000128829 ENSG00000011451 ENSG00000147576 ENSG00000127054 ENSG00000143919 ENSG00000180638 ENSG00000136152 ENSG00000070182 ENSG00000090621 ENSG00000140044 ENSG00000181555 ENSG00000136709 ENSG00000124275 ENSG00000284099 ENSG00000143258 ENSG00000137834 ENSG00000174740 ENSG00000274145 ENSG00000117322 ENSG00000116984 ENSG00000136099 ENSG00000160685 ENSG00000173898 ENSG00000164756 ENSG00000170653 ENSG00000196092 ENSG00000055609 ENSG00000102974 PMC11583782__F1 Predicted pathway and gene network in the treatment of AD with Jiawei Qifuyin ENSG00000105329 ENSG00000140505 ENSG00000087085 ENSG00000171791 ENSG00000164305 ENSG00000274542 ENSG00000180210 ENSG00000151834 ENSG00000112038 ENSG00000133019 ENSG00000184845 ENSG00000125538 ENSG00000120251 ENSG00000275565 ENSG00000276996 ENSG00000120903 ENSG00000132906 ENSG00000180720 ENSG00000100906 ENSG00000081248 ENSG00000173039 ENSG00000065559 ENSG00000007908 ENSG00000140465 ENSG00000073756 ENSG00000102468 ENSG00000043591 ENSG00000007171 ENSG00000132170 ENSG00000274247 ENSG00000111537 ENSG00000177606 ENSG00000108344 PMC7914934__F2 Proteomics Complementation of the Rat Uterotrophic Assay for Estrogenic Endocrine Disruptors: A Roadmap of Advancing High Resolution Mass Spectrometry-Based Shotgun Survey to Targeted Biomarker Quantifications ENSG00000099204 ENSG00000069431 ENSG00000075142 ENSG00000057593 ENSG00000254445 ENSG00000196743 ENSG00000011485 ENSG00000144354 ENSG00000116120 PMC6524659__F2 Time-Resolved Systems Medicine Reveals Viral Infection-Modulating Host Targets ENSG00000104856 ENSG00000169248 ENSG00000162711 ENSG00000213928 ENSG00000002330 ENSG00000187608 ENSG00000102871 ENSG00000198793 ENSG00000160710 ENSG00000164305 ENSG00000134321 ENSG00000088888 ENSG00000140464 ENSG00000164342 ENSG00000132906 ENSG00000132109 ENSG00000125826 ENSG00000125347 ENSG00000127191 ENSG00000276561 ENSG00000007171 ENSG00000169245 ENSG00000275214 ENSG00000067066 ENSG00000105397 ENSG00000144895 ENSG00000135828 ENSG00000121060 PMC3048558__F7 Proposed mechanism of gene regulation in response to extracellular and intracellular dsRNA stimulation ENSG00000104856 ENSG00000173039 ENSG00000164342 PMC9005749__F2 CD155/TIGIT in Digestive Cancers: Promising Cancer Target for Immunotherapy ENSG00000181847 ENSG00000150637 PMC5771804__F4 GD T cells in homeostasis and host defence of epithelial barrier tissues ENSG00000138755 ENSG00000172936 PMC11574213__F3 New insights into crosstalk between Nrf2 pathway and ferroptosis in lung disease ENSG00000151012 ENSG00000181019 ENSG00000178573 ENSG00000167468 ENSG00000164362 ENSG00000168610 ENSG00000079999 PMC1350949__F7 Proposed model of the HCMV-induced apoptotic signaling pathways ENSG00000149311 ENSG00000132906 ENSG00000175054 ENSG00000164305 PMC7774741__F1 Flow chart for selecting SNPs in retinol metabolism pathway genes ENSG00000184254 ENSG00000178573 PMC8037152__F1 Leukemic microenvironment supports survival of acute lymphoblastic leukemia (ALL) cells and their immune evasion through multiple interactions ENSG00000178860 ENSG00000107562 ENSG00000091972 ENSG00000121966 PMC8043392__F11 Coordinated changes in the expression of Wnt pathway genes following human and rat peripheral nerve injury ENSG00000134982 ENSG00000168036 ENSG00000168646 PMC5738696__F1 IGF1R signaling pathway and its relevant drug resistance mechanisms: Promoting proliferation, inhibiting apoptosis and inducing changes to ABC transporter proteins and the ECM ENSG00000169047 ENSG00000163453 ENSG00000185591 ENSG00000140443 PMC2639705__F9 Two Chromogranin A-Derived Peptides Induce Calcium Entry in Human Neutrophils by Calmodulin-Regulated Calcium Independent Phospholipase A2 ENSG00000145321 PMC7754042__F7 miR‐218 could inhibit OSCC proliferation, migration, invasion, EMT and liver metastasis through the TGF‐B signalling pathway by regulating GREM1 PMC8353397__F10 Antiatherogenic Effects of Quercetin in the THP-1 Macrophage Model In Vitro, With Insights Into Its Signaling Mechanisms Using In Silico Analysis ENSG00000226275 ENSG00000291603 ENSG00000102871 ENSG00000196591 PMC9093074__F2 Dual-Targeted Therapy Circumvents Non-Genetic Drug Resistance to Targeted Therapy ENSG00000149311 ENSG00000175054 ENSG00000291971 PMC6989439__F2 Cellular-mediated rejection ENSG00000198053 ENSG00000134982 ENSG00000155926 PMC6989439__F3 Coagulation cascade related to xenotransplantation ENSG00000003436 ENSG00000110799 ENSG00000134982 ENSG00000173599 PMC8945550__F1 Cutting-Edge Therapies and Novel Strategies for Acute Intermittent Porphyria: Step-by-Step towards the Solution ENSG00000110711 ENSG00000256269 PMC6888641__F1 PI3K/mTOR signaling cascade ENSG00000100150 ENSG00000177169 ENSG00000002330 ENSG00000177606 ENSG00000136997 ENSG00000171791 ENSG00000118971 PMC11174581__F1 Promotion mechanisms of microecologics on sports performance ENSG00000163235 ENSG00000169884 ENSG00000096717 PMC8853618__F14 SPOCK1 Promotes the Development of Hepatocellular Carcinoma ENSG00000291971 ENSG00000135446 ENSG00000152377 ENSG00000146648 PMC3005023__F1 Hypoxia and hypoxia-inducible factors (HIFs): master regulators of metastasis ENSG00000169554 ENSG00000148400 ENSG00000148926 ENSG00000112715 ENSG00000121966 ENSG00000007171 ENSG00000071564 ENSG00000167772 ENSG00000134086 ENSG00000100387 ENSG00000122691 ENSG00000163235 ENSG00000146678 ENSG00000154188 PMC1876599__F3 Functional and biological properties of the nuclear receptor coregulator PELP1/MNAR ENSG00000196591 ENSG00000188612 ENSG00000168610 ENSG00000141456 ENSG00000167701 PMC8126563__F3 Protein kinase CK2: a potential therapeutic target for diverse human diseases ENSG00000113558 PMC3714263__F6 ERK Positive Feedback Regulates a Widespread Network of Tyrosine Phosphorylation Sites across Canonical T Cell Signaling and Actin Cytoskeletal Proteins in Jurkat T Cells ENSG00000065833 ENSG00000213658 ENSG00000010810 ENSG00000113263 ENSG00000124181 ENSG00000082212 ENSG00000141968 PMC8126563__F1 Protein kinase CK2: a potential therapeutic target for diverse human diseases ENSG00000168036 ENSG00000168610 PMC8126563__F2 Protein kinase CK2: a potential therapeutic target for diverse human diseases ENSG00000144895 ENSG00000105401 ENSG00000198576 ENSG00000118777 ENSG00000140464 PMC8091781__F10 COXIBs and 2,5-dimethylcelecoxib counteract the hyperactivated Wnt/Beta-catenin pathway and COX-2/PGE2/EP4 signaling in glioblastoma cells ENSG00000111859 ENSG00000089685 ENSG00000134982 ENSG00000168036 PMC3708893__F5 Oral Neutrophil Transcriptome Changes Result in a Pro-Survival Phenotype in Periodontal Diseases ENSG00000183735 ENSG00000157933 ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000115317 ENSG00000026103 PMC7183876__F2 MiR-21 and miR-17~92 promote cyst growth ENSG00000008710 ENSG00000198793 PMC4510836__F1 Complement cascade and its regulators ENSG00000039537 ENSG00000113600 ENSG00000203710 ENSG00000117335 ENSG00000166278 PMC4510836__F2 Complement activation on allograft injury ENSG00000111537 ENSG00000134982 ENSG00000117322 ENSG00000084774 PMC8935220__SF1 Urolithin A protects against acetaminophen-induced liver injury in mice via sustained activation of Nrf2 ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC12121617__F7 BNC1 acts on the CCL20 promoter to suppress the expression of CCL20 in GC cells ENSG00000169594 ENSG00000168610 ENSG00000115009 ENSG00000112486 PMC7590238__F1 ICL repair pathway at different cell cycle phases ENSG00000154920 ENSG00000144554 ENSG00000188827 ENSG00000276787 ENSG00000136936 PMC6417502__F8 Collagen upregulates MMP-14 through activation of the TGFB/TBRI/Smad3/Snail pathway ENSG00000291971 ENSG00000168036 PMC7461207__F3 Mechanotransduction signalling for osteogenesis of human mesenchymal stem cells (hMSCs) ENSG00000170365 PMC10816924__F7 KLF10 in cardiac fibrosis ENSG00000145839 ENSG00000171791 ENSG00000155090 PMC3883721__F1 Phosphoinositide-3 kinase (PI3K) is a heterodimer consisting of p85 and p110 subunits ENSG00000198793 PMC4359534__F7 Cardiovascular disease, lipid metabolism, molecular transport ENSG00000101670 ENSG00000152785 ENSG00000186480 ENSG00000124205 ENSG00000134531 PMC7542480__F4 Protein-protein interaction network ENSG00000140992 ENSG00000165841 ENSG00000188257 ENSG00000227345 ENSG00000126432 ENSG00000158125 PMC4359534__F8 Cell-cell signaling and interaction, molecular transport, small molecular biochemistry ENSG00000136250 ENSG00000111859 ENSG00000162761 ENSG00000043591 PMC6332742__F1 The central role of C1 inhibitor in various plasma systems., Upon contact with negatively charged surfaces factor XII (FXII) is (auto‐) activated to activated factor XIIa (FXIIa) ENSG00000288512 ENSG00000122194 ENSG00000182326 ENSG00000137509 PMC2728144__F6 Schematic diagram depicting our findings on the post-transcriptional regulation of CXCR4 in MCF7-HER2 cells as a result of estrogen and HER2 cross-talk and the involvement of activated PI3K and MAPK pathways and TSC2 (tuberin) ENSG00000124102 ENSG00000198793 ENSG00000121966 PMC8894804__F1 ULK1 Signaling in the Liver: Autophagy Dependent and Independent Actions ENSG00000069509 ENSG00000108443 ENSG00000079999 PMC5362561__F1 Scheme of the metabolic pathway of purines and their relation to hypoxanthine-guanine-phosphoribosyltransferase (HPRT) ENSG00000196839 ENSG00000291814 PMC8885406__F3 XPO1 mediated emergent drug resistance pathways ENSG00000131747 ENSG00000168036 PMC4991833__F4 Simplified model for the symbiotic signaling pathway in legumes ENSG00000125450 ENSG00000069248 PMC4391565__F10 H3K56 acetylation prevents genomic instability by affecting Ctf4 function ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000177084 ENSG00000166508 PMC7787056__F4 Duality of human oncoproteins: drivers of cancer and congenital disorders ENSG00000157404 ENSG00000146648 PMC7108731__F1 Influence of rare variants in circulating metabolic biomarkers ENSG00000172840 ENSG00000005882 ENSG00000090857 PMC6302517__F3 Schematic illustrating the role of cav-1 in different cell ENSG00000172936 ENSG00000136869 PMC7326806__F5 Reciprocal regulation between brain cancer and neuronal cells in the brain ENSG00000142192 ENSG00000137845 PMC4694672__F7 Silk + bLf NPs induced apoptosis in EGFR +ve and EGFR −ve cells.Notes: Internalization of both forms of nanoformulation was facilitated via LRP1 receptors and EGFR in MDA-MB-231 cells and via death receptors in MCF-7 cells ENSG00000214285 ENSG00000146648 ENSG00000026103 PMC7326806__F3 Overlapping molecules in cancer and neurodegenerative diseases ENSG00000127445 ENSG00000142192 ENSG00000181019 ENSG00000123374 PMC8032583__F1 Serum 4Beta-hydroxycholesterol increases during fluconazole treatment ENSG00000001630 ENSG00000116133 ENSG00000104549 PMC4664252__F9 Distinct Upstream Role of Type I IFN Signaling in Hematopoietic Stem Cell-Derived and Epithelial Resident Cells for Concerted Recruitment of Ly-6Chi Monocytes and NK Cells via CCL2-CCL3 Cascade ENSG00000108691 ENSG00000163565 ENSG00000277943 PMC7145987__F4 DNA damage response defects in high risk neuroblastoma (HR-NB) ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000178999 ENSG00000197299 ENSG00000149554 PMC8360618__F3 MUC1 is an oncoprotein with a significant role in apoptosis (Review) ENSG00000168040 ENSG00000026103 PMC4600855__F1 S-nitrosylation in TRAIL/DR4 and FaL/Fas signaling pathways ENSG00000100811 ENSG00000132906 ENSG00000168040 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC7593679__F1 TRP and its key catabolites (TRYCATs) produced via three biochemical pathways: the kynurenine pathway, tryptamine pathway, and serotonin pathway ENSG00000262635 ENSG00000129167 ENSG00000188676 PMC4600855__F2 S-nitrosylation in classical TNF-NF-kB signaling ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000064012 PMC2435380__F1 Methionine metabolic pathway PMC4600855__F3 S-nitrosylation in TNF-JNK-AP-1 signaling ENSG00000102871 ENSG00000127191 PMC8526538__F8 Lysosomal-Associated Protein Transmembrane 5 Functions as a Novel Negative Regulator of Pathological Cardiac Hypertrophy ENSG00000159182 PMC5995375__F8 Endothelial cell activation is attenuated by everolimus via transcriptional and post-transcriptional regulatory mechanisms after drug-eluting coronary stenting ENSG00000007908 ENSG00000162692 PMC11039397__F7 Mechanism diagram of SR1 alleviating bone lossIn the natural environment, air pollutants contain different AhR ligands ENSG00000110711 ENSG00000147614 ENSG00000164935 ENSG00000102575 ENSG00000175104 ENSG00000131196 ENSG00000106546 ENSG00000143387 PMC8555053__F4 On the role of dauer in the adaptation of nematodes to a parasitic lifestyle ENSG00000118515 ENSG00000189430 PMC7400736__F3 Interaction network of the let-7 family targeting the IGF family members generated from HMDD version 3 ENSG00000081181 ENSG00000105392 ENSG00000106367 ENSG00000161405 ENSG00000181104 ENSG00000163064 ENSG00000171791 ENSG00000164305 ENSG00000124762 ENSG00000117713 ENSG00000113328 ENSG00000116106 ENSG00000117400 ENSG00000140443 ENSG00000198625 ENSG00000143632 PMC11923913__F7 Cellular mechanisms, signaling pathways, and potential therapeutic targets in TRALI ENSG00000154133 ENSG00000189403 ENSG00000121966 PMC7400736__F4 Crosstalk between the insulin/IGF signalling pathways and the potential targeting of let-7 ENSG00000107018 ENSG00000172410 ENSG00000171105 ENSG00000120210 ENSG00000129965 ENSG00000107014 ENSG00000288474 ENSG00000116183 ENSG00000115457 ENSG00000167779 ENSG00000141753 ENSG00000146678 ENSG00000115461 PMC7150862__F8 Schematic model of miR-202-5p-mediated RIG-I-like receptors (RLRs) signaling pathway during viral infection ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000175104 ENSG00000121060 PMC514698__F1 Known Yeast Cell Cycle Interactions ENSG00000261832 ENSG00000094804 ENSG00000117399 PMC4286601__F1 Main glucose degradation pathways in the heart PMC6193168__F5 Involvement of mitophagy in the transportation of amorphous calcium phosphate (ACP) precursors from the mitochondria to the extracellular matrix in stem cells with osteogenic potential ENSG00000170365 ENSG00000198742 ENSG00000005893 ENSG00000158828 PMC5045388__F4 Acquired resistance to combination treatment through loss of synergy with MEK and PI3K inhibitors in colorectal cancer ENSG00000198793 PMC7993678__F6 Cancer associated fibroblasts (CAFs) from osimertinib-resistant patients promoted osimertinib resistance via HGF/MET signaling and induction of epithelial-to-mesenchymal transition (EMT) and transformed NSCLC cells into TKI resistant stem-like cells ENSG00000019991 ENSG00000168036 ENSG00000146648 PMC5852508__F6 Proposed central and peripheral pathways/mechanisms being activated by circulating Ang II and high dietary salt intake PMC11923913__F5 Signaling pathways in TRALI ENSG00000107562 ENSG00000145147 ENSG00000154133 ENSG00000198793 ENSG00000189403 ENSG00000136869 ENSG00000121966 PMC3322580__F4 Enrichment and submodularization of cell cycle in terms of E3-mediated regulatory modules ENSG00000170458 ENSG00000132646 ENSG00000077279 ENSG00000164754 ENSG00000117399 ENSG00000274473 PMC11923913__F6 TRALI‐targeting therapies ENSG00000198793 ENSG00000189403 ENSG00000153029 ENSG00000136869 ENSG00000121966 PMC2974215__F2 TNF-dependent signalling pathways mediated through TNFR1 and TNFR2 ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC10518396__F7 Overcoming the therapeutic limitations of EZH2 inhibitors in Burkitt’s lymphoma: a comprehensive study on the combined effects of MS1943 and Ibrutinib ENSG00000186716 ENSG00000010671 PMC4086337__F1 NLRP3 inflammasome regulates the caspase-1 dependent maturation and secretion of pro-inflammatory cytokines ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC3377094__F2 Regulation of innate immune signalling pathways by the tripartite motif (TRIM) family proteins ENSG00000132109 ENSG00000113595 ENSG00000140968 ENSG00000173039 ENSG00000150455 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000157625 ENSG00000136869 ENSG00000172936 ENSG00000175104 ENSG00000164342 PMC11673339__F5 Search for pathways that reflect gene expression effects of Semax and ACTH(6–9)PGP at 24 h after tMCAO in FC ENSG00000122877 ENSG00000146648 PMC3170448__F5 Simply comparing and contrasting the expression patterns of perturbed genes was inadequate for deciphering the MAPK pathway response dynamics ENSG00000140285 PMC6287148__F1 Mitogen-activated protein kinase pathway ENSG00000157764 ENSG00000146648 PMC6036835__F5 KEGG pathway (FDR < 0.05) enriched by the 289 differentially expressed genes in drug group compared to model group ENSG00000112695 ENSG00000112651 ENSG00000134419 ENSG00000109475 ENSG00000189043 ENSG00000145592 ENSG00000105605 ENSG00000108826 ENSG00000160471 PMC4461477__F5 Emerging molecular machinery and therapeutic targets of metastasis ENSG00000087245 ENSG00000162692 PMC1958996__F2 Transcriptional control of adipocyte formation ENSG00000135446 ENSG00000205250 PMC11889691__S1 Multiscale mechanical-adapted hydrogel for the repair of IVDD ENSG00000149968 ENSG00000100985 ENSG00000128928 PMC8220440__F2 Multifunctional inhibitors of SARS-CoV-2 by MM/PBSA, essential dynamics, and molecular dynamic investigations ENSG00000102871 ENSG00000125538 ENSG00000128342 PMC11677934__F8 Essential Role of Cortactin in Myogenic Differentiation: Regulating Actin Dynamics and Myocardin-Related Transcription Factor A-Serum Response Factor (MRTFA-SRF) Signaling PMC8220440__F3 Multifunctional inhibitors of SARS-CoV-2 by MM/PBSA, essential dynamics, and molecular dynamic investigations ENSG00000056558 ENSG00000131323 ENSG00000127191 PMC9661523__F4 Non-cardiomyocytes in the heart in embryo development, health, and disease, a single-cell perspective ENSG00000125266 ENSG00000135218 ENSG00000162493 ENSG00000117707 ENSG00000140092 ENSG00000198732 ENSG00000010319 ENSG00000146374 ENSG00000108691 ENSG00000140937 ENSG00000128917 ENSG00000102760 ENSG00000131196 ENSG00000167434 PMC6527283__F2 Interaction of tumor-associated macrophages and cancer chemotherapy ENSG00000168610 PMC2213208__F1 Activation of the vagus nerve leads to the release of acetylcholine (Ach) that binds to Alpha-7 nicotinic receptors (A7 nAChR) on cytokine producing cells ENSG00000189403 ENSG00000168610 PMC9493050__F7 Calcium dobesilate efficiency in the treatment of diabetic kidney disease through suppressing MAPK and chemokine signaling pathways based on clinical evaluation and network pharmacology ENSG00000117020 ENSG00000102871 ENSG00000291971 ENSG00000177606 ENSG00000127191 ENSG00000164305 PMC2860555__F1 Endosomal and cytoplasmic pathways for virus recognition and IFN production ENSG00000183735 ENSG00000088888 ENSG00000172936 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC9693603__F11 Inhibition of NF-kB/IL-6/JAK2/STAT3 Pathway and Epithelial-Mesenchymal Transition in Breast Cancer Cells by Azilsartan ENSG00000171791 ENSG00000100985 ENSG00000168610 PMC8668986__F10 Metastasis suppressor NDRG1 directly regulates androgen receptor signaling in prostate cancer ENSG00000105397 ENSG00000168610 PMC5496137__F1 Central metabolic pathways of E ENSG00000122966 PMC4726471__F2 Interplay Between Centrosomes and the Hippo Tumor Suppressor Pathway ENSG00000150457 ENSG00000131023 PMC5700047__F8 Proposed model of CHK1 as a facilitator of transformation and drug target ENSG00000136997 ENSG00000171791 PMC11019653__F7 Effect of 23‑hydroxybetulinic acid on lung adenocarcinoma and its mechanism of action ENSG00000073756 PMC11354767__F6 GPR30 signaling pathway ENSG00000291971 ENSG00000113070 ENSG00000168610 ENSG00000146648 PMC3466049__F1 Complement-targeted therapeutics in periodontitis ENSG00000174125 ENSG00000111537 ENSG00000170458 ENSG00000136869 ENSG00000125347 ENSG00000121966 PMC4359534__F9 Lipid metabolism, molecular transport, small molecule biochemistry ENSG00000168530 ENSG00000125740 ENSG00000141448 ENSG00000120088 ENSG00000110680 ENSG00000107611 ENSG00000135914 PMC2761008__F2 Minimum spanning tree of the network associated with cancer pathway genes ENSG00000182481 ENSG00000171791 ENSG00000064300 ENSG00000103811 ENSG00000103479 ENSG00000071082 ENSG00000123374 ENSG00000163017 ENSG00000143333 ENSG00000172201 ENSG00000166974 ENSG00000142192 ENSG00000185022 ENSG00000112964 ENSG00000125148 ENSG00000113070 ENSG00000149091 ENSG00000173039 ENSG00000124766 ENSG00000116741 ENSG00000118816 ENSG00000073921 ENSG00000081189 ENSG00000119048 ENSG00000149311 ENSG00000136603 ENSG00000177189 ENSG00000134574 ENSG00000132646 ENSG00000175305 PMC2761008__F3 Cliques or near cliques from the cancer pathway related network Gp ENSG00000105329 ENSG00000242252 ENSG00000182899 ENSG00000136271 ENSG00000112118 ENSG00000137801 ENSG00000136603 ENSG00000149311 ENSG00000103479 ENSG00000071082 ENSG00000123374 ENSG00000163017 ENSG00000172201 PMC6422174__F1 Linking Signaling and Selection in the Germinal Center ENSG00000150907 PMC11200706__F2 Coloration in Equine: Overview of Candidate Genes Associated with Coat Color Phenotypes ENSG00000168036 ENSG00000080166 ENSG00000107165 PMC3101816__F1 The central role of cIAP1 in NFKB signalling and programmed cell death ENSG00000102871 ENSG00000168040 ENSG00000112186 ENSG00000127191 PMC7133220__F9 Putative mechanisms by which neratinib down-regulates mutant K-RAS expression and inactivates Hippo Pathway function ENSG00000149311 ENSG00000150457 ENSG00000131023 PMC5348443__F2 Kinase inhibitors as potential agents in the treatment of multiple myeloma ENSG00000104856 ENSG00000173039 PMC6386826__F1 Signaling transduction of mTOR pathway ENSG00000198793 ENSG00000118515 ENSG00000164327 ENSG00000167965 PMC10476361__F6 HDAC5 regulates MEF2A expression by influencing the ERK/EGR1 signaling pathwayVentricular remodeling induces cytoplasm translocation of HDAC5 ENSG00000108840 PMC4437987__F1 Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in Human Brain Tumors ENSG00000167965 ENSG00000146648 PMC5488651__F3 Bacterium Helicobacter pylori is a well-studied example of a pathogen manipulating host PAK1 signalling ENSG00000149269 ENSG00000125538 ENSG00000136869 PMC8476122__F2 Pembro enhances Gln uptake/release of glutaminolytic products while blocking Gln-fueled Krebs cycle activity in primary CA but not in NC lung tissues ENSG00000166278 ENSG00000115419 PMC3442865__F1 TOR pathway activation ENSG00000198793 PMC4336822__F1 Progesterone action in breast, uterine, and ovarian cancers ENSG00000123374 PMC8058565__F5 Sulfation of 25HC as an epigenetic regulatory pathway ENSG00000182533 ENSG00000002330 ENSG00000113161 ENSG00000096717 PMC8917703__F2 Improvement of the anticancer efficacy of PD-1/PD-L1 blockade via combination therapy and PD-L1 regulation ENSG00000169245 ENSG00000186810 ENSG00000183735 ENSG00000164430 ENSG00000183723 ENSG00000134982 ENSG00000175591 ENSG00000173039 ENSG00000089041 ENSG00000136869 ENSG00000162692 ENSG00000142166 PMC4355395__F4 The 12/15Lipoxygenase as an emerging therapeutic target for Alzheimer's disease ENSG00000142192 ENSG00000185591 PMC4336822__F3 Progesterone action in breast, uterine, and ovarian cancers ENSG00000164107 ENSG00000163501 PMC6851227__F1 Metabolic alterations in AML blasts ENSG00000198793 ENSG00000115419 ENSG00000159399 ENSG00000062485 PMC6503643__F2 HSVs modulate antiviral mechanisms related to cell death in non-immune cells ENSG00000213658 ENSG00000144895 PMC6851227__F2 Enhanced tryptophan-turnover in AML blasts ENSG00000198793 ENSG00000106546 PMC6503643__F4 HSV proteins modulate key steps in interferon-related pathways ENSG00000005339 ENSG00000115415 ENSG00000131323 ENSG00000276561 PMC6503643__F5 HSVs interfere with antiviral processes in innate immune cells ENSG00000174125 ENSG00000183735 ENSG00000158473 ENSG00000164430 ENSG00000124155 ENSG00000204520 PMC9605425__F5 Sponge-Derived Brominated Compound Aeroplysinin-1 Impairs the Endothelial Inflammatory Response through Inhibition of the NFKB Pathway ENSG00000108691 ENSG00000173039 ENSG00000162692 PMC5482757__F4 Emerging Role of MicroRNAs in mTOR Signaling ENSG00000113360 PMC4259450__F2 Mutational profiles in triple-negative breast cancer defined by ultradeep multigene sequencing show high rates of PI3K pathway alterations and clinically relevant entity subgroup specific differences ENSG00000135446 ENSG00000198793 ENSG00000136997 ENSG00000123374 ENSG00000105810 ENSG00000146648 PMC2695826__F2 Age-Related Decrease in Proteasome Expression Contributes to Defective NFKB Activation during Hepatic Ischemia/Reperfusion ENSG00000169919 ENSG00000132341 PMC3772092__F7 Cadherin 6 Is a New RUNX2 Target in TGFB Signalling Pathway ENSG00000124216 ENSG00000166589 ENSG00000041982 ENSG00000019549 ENSG00000113361 ENSG00000125968 PMC5482757__F1 Emerging Role of MicroRNAs in mTOR Signaling ENSG00000198793 ENSG00000164327 PMC7718880__F8 Schematic diagram illustrates the mechanism for the effect of the oxalate/LCN2/ERK and p-ERK and the expressions of LCN2, PTGS1, GPX3 and MMD axises on renal epithelial cell damage during kidney stone formation ENSG00000211445 ENSG00000148346 ENSG00000108960 ENSG00000095303 PMC5482757__F2 Emerging Role of MicroRNAs in mTOR Signaling ENSG00000168209 PMC2695826__F1 Ingenuity pathway analysis identified a network of genes down regulated in response to 60 minutes of ischemia in aged mouse liver ENSG00000162613 ENSG00000134480 PMC4037130__F1 Targeting protein prenylation for cancer therapy ENSG00000002330 ENSG00000070831 ENSG00000156299 ENSG00000163914 PMC5482757__F3 Emerging Role of MicroRNAs in mTOR Signaling ENSG00000168209 ENSG00000135932 PMC10870461__F16 Signal pathways related to CALD1 mapped by KEGG database ENSG00000160013 ENSG00000148926 ENSG00000173786 ENSG00000151617 ENSG00000084774 PMC6676344__F2 Graphical summary of the anticancer mechanisms of formononetin ENSG00000157554 ENSG00000066468 ENSG00000291971 ENSG00000123374 ENSG00000168610 ENSG00000182580 ENSG00000140443 PMC8292425__F1 Sequence variant in the diacylglycerol O-acyltransferase 2 gene influences palmitoleic acid content in pig muscle ENSG00000168282 ENSG00000285482 ENSG00000099194 ENSG00000062282 PMC7851265__F3 rTSMS regulates functional protein synthesis and pathways ENSG00000182718 ENSG00000015592 ENSG00000070831 ENSG00000143878 ENSG00000020129 ENSG00000197971 ENSG00000117118 ENSG00000176788 ENSG00000175426 ENSG00000154096 ENSG00000237834 PMC6551881__F8 Over-expression of miR-195-5p blocks the PSAT1-mediated GSK3B/Beta-catenin signaling pathway, thus inhibiting angiogenesis and reducing chemotherapy resistance to DDP ENSG00000168036 ENSG00000135069 PMC8308291__F1 Omega-3 Supplementation and Heart Disease: A Population-Based Diet by Gene Analysis of Clinical Trial Outcomes ENSG00000134824 ENSG00000196839 ENSG00000149485 ENSG00000197977 PMC9554963__F1 Improving cancer immunotherapy by rationally combining oncolytic virus with modulators targeting key signaling pathways ENSG00000144895 ENSG00000136997 ENSG00000146648 PMC3343318__F6 PLC signaling in B cells ENSG00000095585 ENSG00000167323 ENSG00000198838 ENSG00000186716 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000010671 PMC8364365__F5 Crucial Roles of Intermediate Metabolites in Cancer ENSG00000183077 ENSG00000106546 PMC8273223__F1 Etoposide, an anticancer drug involved in therapy-related secondary leukemia: Enzymes at play ENSG00000005381 PMC8014161__F11 Network Meta‐Analysis on the Mechanisms Underlying Alcohol Augmentation of COVID‐19 Pathologies ENSG00000213658 ENSG00000189403 ENSG00000132478 ENSG00000145020 ENSG00000168610 PMC5697091__F7 List of genes involved in Toll-like receptor pathway generated by KEGG of the differently expressed genes between Cryptocaryon irritans-infected and non-infected S ENSG00000239732 ENSG00000144410 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 ENSG00000143387 PMC9305664__F2 Non-Coding RNAs in Primary Biliary Cholangitis ENSG00000136535 ENSG00000118707 PMC5697091__F8 List of genes involved in Toll-like receptor pathway generated by KEGG of the differently expressed genes between Cryptocaryon irritans-infected and non-infected S ENSG00000239732 ENSG00000144410 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000164342 ENSG00000143387 PMC5697091__F9 List of genes involved in the complement and coagulation cascades pathway generated by KEGG of the differently expressed genes between C ENSG00000039537 ENSG00000003436 ENSG00000113600 ENSG00000110799 ENSG00000166278 ENSG00000122194 ENSG00000117322 ENSG00000185010 ENSG00000180210 ENSG00000126218 ENSG00000112977 ENSG00000101981 ENSG00000117525 ENSG00000173599 ENSG00000057593 ENSG00000175899 ENSG00000080618 ENSG00000062485 PMC7285805__F1 STAT6 modulates pro-colitis and pro-cancer responses PMC7285805__F2 Targeting the IL-4/IL-13/STAT6 signaling pathway for cancer therapy ENSG00000123496 ENSG00000105397 ENSG00000131724 ENSG00000105639 PMC5712330__F3 Canonical and non-canonical NFKB signaling pathways ENSG00000023445 ENSG00000104856 ENSG00000110330 ENSG00000186716 ENSG00000173039 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000184216 ENSG00000198286 PMC5712330__F4 Regulation of the NFKB signaling pathway by MALT1 and BIRC3-MALT1 ENSG00000023445 ENSG00000104856 ENSG00000118503 ENSG00000173039 ENSG00000083799 ENSG00000175104 ENSG00000127191 ENSG00000198286 PMC5712330__F5 Targeted therapy in extranodal marginal zone lymphoma ENSG00000023445 ENSG00000118503 ENSG00000161405 ENSG00000186716 ENSG00000198793 ENSG00000136997 ENSG00000137265 ENSG00000172936 ENSG00000175104 ENSG00000198286 PMC7957700__F1 Normal CD8+ T Cell Response ENSG00000291603 ENSG00000104894 PMC6045948__F2 Signal transduction pathways involving c-fos PMC3905229__F2 Wnt/GSK- 3B pathway ENSG00000134982 PMC9234177__F7 Allicin in Digestive System Cancer: From Biological Effects to Clinical Treatment ENSG00000168610 PMC6107220__F1 Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies ENSG00000088826 ENSG00000148832 ENSG00000116649 ENSG00000102172 PMC8147372__F6 Transcriptomic and metabolomic characterization of post-hatch metabolic reprogramming during hepatic development in the chicken ENSG00000141349 ENSG00000160883 ENSG00000067057 ENSG00000073578 ENSG00000122966 ENSG00000278373 ENSG00000117118 ENSG00000235376 ENSG00000153574 ENSG00000105953 ENSG00000131828 ENSG00000143252 ENSG00000173599 ENSG00000172005 ENSG00000091140 ENSG00000152556 ENSG00000062485 PMC8875399__F1 F ig . 1.“Find-me” signals and their respective receptors for apoptotic and necrotic cells ENSG00000168329 ENSG00000163739 ENSG00000170989 ENSG00000180739 ENSG00000140545 ENSG00000213694 ENSG00000125910 ENSG00000110218 ENSG00000267534 ENSG00000171051 ENSG00000137801 PMC3898811__F7 Schematic diagram as summary of the present investigation ENSG00000087245 ENSG00000100985 PMC4581028__F1 Regulation of cell metabolism by proto-oncogenes and tumour suppressors ENSG00000136997 PMC7874475__F9 Protein-protein interaction network ENSG00000163935 ENSG00000065911 ENSG00000169554 ENSG00000197275 ENSG00000169439 ENSG00000148541 ENSG00000122786 ENSG00000166147 ENSG00000093009 ENSG00000138035 ENSG00000140937 ENSG00000178573 ENSG00000038427 ENSG00000109805 ENSG00000116132 ENSG00000130508 PMC9513389__F1 Cooperation effects of radiation and ferroptosis on tumor suppression and radiation injury ENSG00000167468 ENSG00000111684 ENSG00000102967 ENSG00000115107 ENSG00000127948 PMC3607786__F1 MTOR signal pathway in autism spectrum disorders PMC8888700__F5 Environment-dependent oncogenic activities of PcG proteins ENSG00000198901 ENSG00000142192 ENSG00000108691 ENSG00000231179 ENSG00000204520 ENSG00000121807 ENSG00000179348 ENSG00000145088 PMC4048946__F1 Metabolic pathways regulating oxidative stress and endosome traffic controlling the recycling of receptor and adaptor proteins between the cell surface and lysosomes ENSG00000110395 ENSG00000213658 ENSG00000167323 ENSG00000198793 ENSG00000198087 ENSG00000124181 ENSG00000135517 PMC8638142__F10 LncRNA PKMYT1AR promotes cancer stem cell maintenance in non-small cell lung cancer via activating Wnt signaling pathway ENSG00000100811 ENSG00000134982 PMC8888700__F2 Polycomb recruitment and action on target genes ENSG00000198901 ENSG00000173894 ENSG00000140320 ENSG00000162521 ENSG00000074266 ENSG00000008083 PMC4490472__F2 Regulation of CUL5, JAG-NOTCH, TNKS2, and PTEN-PI3K-AKT cell signaling by members of miR-17~92 and miR-106a~363 clusters in cervical cancer ENSG00000145604 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000166266 ENSG00000173273 PMC5923449__F2 EV71 induces multiple cellular inflammatory signals and Ca2+-dependent signals ENSG00000291971 ENSG00000138798 ENSG00000177606 ENSG00000157625 PMC4490472__F3 Regulation of JAG1-NOTCH1-uPA, Cyclin D-CDK4/6-p21-p27, and PI3K-PDK1-AKT1 cell signaling by members of the miR-23b~27b~24-1, miR-29a~29b-1, miR-29b-2~29c, miR17~92, miR183~96~182, and miR-302s clusters ENSG00000145604 ENSG00000100811 ENSG00000135446 ENSG00000150907 ENSG00000105810 ENSG00000122194 PMC4490472__F1 Regulation of MAPK, PI3K-AKT, and G2-M checkpoint by members of the family miR-125 and members of miR-let-7c~99a, miR-125a~let-7e~99b, miR-100~let-7a-2, and miR-206~133b clusters in cervical cancer ENSG00000149311 ENSG00000175054 ENSG00000071575 ENSG00000070831 ENSG00000198793 ENSG00000087586 ENSG00000166851 PMC4784301__F4 Synthetic model of Plasmodium quiescence metabolism ENSG00000073578 ENSG00000107798 ENSG00000166278 ENSG00000062485 PMC12110659__F4 Targeting autophagy to enhance anti-PD-1/PD-L1 therapy ENSG00000188554 ENSG00000026508 PMC9002053__F3 Translational Control of COVID-19 and Its Therapeutic Implication ENSG00000163435 ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000120690 ENSG00000115415 ENSG00000100883 ENSG00000114127 ENSG00000100664 PMC8494307__F7 NLRP3 Inflammasome Activation of Mast Cells by Estrogen via the Nuclear-Initiated Signaling Pathway Contributes to the Development of Endometriosis ENSG00000162711 ENSG00000125538 ENSG00000115594 PMC6850186__F6 How ablation of IKBNS affects B cell activation and PC differentiation ENSG00000186716 ENSG00000173039 ENSG00000136869 PMC12110659__F1 Immune Resistance Mechanisms ENSG00000150782 ENSG00000151882 ENSG00000113520 ENSG00000125347 ENSG00000113525 PMC12110659__F2 Autophagy regulation by glycolysis ENSG00000198793 ENSG00000168610 PMC4030113__F2 Abnormalities in IRS1 interaction in the KEGG PI3K-AKT signaling pathway (PI3K-AKT) ENSG00000132906 ENSG00000168209 ENSG00000002330 ENSG00000119535 ENSG00000105401 ENSG00000198793 ENSG00000169047 ENSG00000108342 ENSG00000213341 ENSG00000171791 ENSG00000107175 ENSG00000160741 ENSG00000177455 ENSG00000103479 ENSG00000136997 ENSG00000069966 PMC2890584__F6 Mu-Opioid Receptors Transiently Activate the Akt-nNOS Pathway to Produce Sustained Potentiation of PKC-Mediated NMDAR-CaMKII Signaling ENSG00000291971 ENSG00000005882 ENSG00000169567 PMC4030113__F3 Abnormalities in IRS1 interaction in the KEGG Oxidative Phosphorylation metabolic pathway ENSG00000073578 ENSG00000130414 ENSG00000117118 ENSG00000138495 ENSG00000169047 ENSG00000292058 ENSG00000004779 ENSG00000006695 ENSG00000267855 ENSG00000143252 ENSG00000131174 ENSG00000213619 ENSG00000065518 ENSG00000151366 ENSG00000184752 ENSG00000186010 ENSG00000015285 ENSG00000099795 PMC3703460__F3 Signaling Pathways That Control mRNA Turnover ENSG00000127445 ENSG00000138798 PMC3703460__F4 Signaling Pathways That Control mRNA Turnover ENSG00000128191 ENSG00000113360 PMC5835061__F1 Schematic presentation of synthesis and maturation of BDNF ENSG00000087245 ENSG00000140564 ENSG00000100985 ENSG00000122194 PMC9547753__F3 Sepsis-induced immunosuppression: mechanisms, diagnosis and current treatment options ENSG00000278718 ENSG00000167468 ENSG00000189403 ENSG00000145782 ENSG00000026103 PMC6209965__F3 Natural compounds as anticancer agents in TNBCs: Mode(s) of Action ENSG00000134982 ENSG00000198793 ENSG00000177606 ENSG00000136997 ENSG00000168036 ENSG00000128602 ENSG00000146648 PMC11005058__F2 Adipocyte leptin promotes lymphocyte activation and TH17 differentiation ENSG00000111537 ENSG00000186716 ENSG00000168610 PMC6737310__F4 Inflammatory mediator network between cytokines and signaling pathway in liver fibrosis ENSG00000168610 PMC6698603__F6 Possible mechanism of drug resistance related to miR-326 in pediatric acute lymphoblastic leukemia (pALL) leukemic cells ENSG00000107331 ENSG00000167972 ENSG00000128602 PMC6976905__F7 Overexpressed lncRNA GATA6-AS1 Inhibits LNM and EMT via FZD4 through the Wnt/Beta-Catenin Signaling Pathway in GC ENSG00000174804 ENSG00000168036 PMC6976905__F1 Overexpressed lncRNA GATA6-AS1 Inhibits LNM and EMT via FZD4 through the Wnt/Beta-Catenin Signaling Pathway in GC ENSG00000174804 ENSG00000168036 PMC10529739__F3 Signalling pathways and transcription factors involved in MSC senescence ENSG00000178860 ENSG00000187531 ENSG00000105835 ENSG00000198793 ENSG00000168036 ENSG00000124523 ENSG00000077463 ENSG00000173614 ENSG00000096717 ENSG00000142082 ENSG00000089163 ENSG00000283100 PMC5105076__F8 Qishen granules inhibit myocardial inflammation injury through regulating arachidonic acid metabolism ENSG00000168610 PMC3365861__F6 Opposing roles of Myd88 and RAGE in extensive liver resection ENSG00000137193 ENSG00000172936 ENSG00000168610 PMC9325148__F2 Succinate as a New Actor in Pluripotency and Early Development? ENSG00000168958 ENSG00000198829 ENSG00000166278 PMC4557106__F3 Pharmacologic modulators of the Hippo pathway ENSG00000134982 ENSG00000163914 ENSG00000176105 ENSG00000150457 ENSG00000131023 ENSG00000089225 PMC1705980__F2 Schematic model of autophagic regulation ENSG00000198793 PMC2134905__F2 The p53 pathway and IGFBP3 PMC6430710__F5 Complementary pathways in DNA double strand (ds) break repair and PARP inhibitor response ENSG00000143799 ENSG00000012048 ENSG00000051180 ENSG00000177084 ENSG00000139618 PMC10743706__F2 Biosynthetic pathways of BR ENSG00000108582 ENSG00000162819 ENSG00000062485 PMC12251215__F3 In esophageal and gastric cancers (EC and GC, respectively), circRNAs modulate Wnt/Beta-catenin signaling through various mechanisms ENSG00000078747 ENSG00000104290 ENSG00000145321 ENSG00000124766 ENSG00000168036 ENSG00000271303 PMC2517296__F1 The co-ordinated activation of pro-inflammatory signalling pathways by TLR ligands and the pro-inflammatory cytokines TNFA, IL-1 and IFN ENSG00000102871 ENSG00000082512 ENSG00000172936 ENSG00000175104 ENSG00000127191 PMC7962935__F1 Downstream signaling of Frizzled proteins (Fzds) ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC12251215__F2 Wnt Signaling Pathways: canonical (Wnt/Beta-catenin) and non-canonical (Wnt/planar cell polarity, PCP and Wnt/Ca2+) pathways ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000100592 ENSG00000134982 ENSG00000185483 ENSG00000168036 PMC3753234__F7 Fibroblast Growth Factor 2 Causes G2/M Cell Cycle Arrest in Ras-Driven Tumor Cells through a Src-Dependent Pathway ENSG00000291971 PMC8314420__F2 Genetic syndromes with vascular malformations – update on molecular background and diagnostics ENSG00000170365 PMC2688657__F5 Growth signal pathway ENSG00000163235 ENSG00000101265 ENSG00000010810 ENSG00000138798 ENSG00000177606 ENSG00000136997 ENSG00000146648 PMC2688657__F3 Apoptosis pathway ENSG00000132906 ENSG00000149311 ENSG00000111057 ENSG00000002330 ENSG00000102871 ENSG00000138794 ENSG00000171791 ENSG00000168040 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC2688657__F1 Antigrowth signaling pathway and cluster around SMAD proteins ENSG00000173156 ENSG00000135446 ENSG00000087365 ENSG00000136997 ENSG00000120693 ENSG00000090060 ENSG00000123374 ENSG00000105810 ENSG00000136235 ENSG00000108671 PMC8282792__F8 Proposed model for the dysregulation DEPDC5-mTORC1 axis in the pathogenesis of alcohol-induced hepatic steatosis ENSG00000100150 ENSG00000099910 PMC3757153__F2 Treatment advances in neonatal neuroprotection and neurointensive care ENSG00000143799 ENSG00000120868 ENSG00000168040 ENSG00000084774 ENSG00000026103 PMC9153171__F2 Metabolomic, proteomic and lactylated proteomic analyses indicate lactate plays important roles in maintaining energy and C:N homeostasis in Phaeodactylum tricornutum ENSG00000122966 ENSG00000172005 ENSG00000062485 PMC7672569__F2 Targeted signalling pathway involved in endothelial cells (ECs) activation and vascular smooth muscle cells (VSMCs) proliferation and migration during intimal hyperplasia ENSG00000082175 ENSG00000291971 ENSG00000112715 PMC7926043__F8 Mapped proteins and genes in the glucocorticoid receptor signaling pathway, the role of JAK2 in the hormone-like cytokine signaling pathway, and the TNFR1 signaling pathway ENSG00000127191 ENSG00000164305 ENSG00000142224 ENSG00000179295 PMC6032287__F1 Phoenixin-20 stimulates the mRNA expression of GnRH, GnRH receptor, Kiss1 peptide, and GRP173 via the cAMP-PKA pathway and CREB phosphorylation mediated by the GPR173 ENSG00000184194 ENSG00000109163 ENSG00000170498 PMC10944245__F9 Cytotoxic effect of flavonoids related to MAPK and PI3KAkt pathways ENSG00000157764 ENSG00000138798 PMC8819497__F9 DDR‐dependent matrix‐mediated drug resistance (MMDR) to MAPK‐targeting therapies in melanoma ENSG00000104856 ENSG00000162733 PMC3899934__F2 Farnesoid X receptor–Acting through bile acids to treat metabolic disorders ENSG00000138075 ENSG00000130164 ENSG00000042832 ENSG00000167910 ENSG00000180432 ENSG00000169174 ENSG00000143921 PMC9673319__F3 Finding memo: versatile interactions of the VPS10p-Domain receptors in Alzheimer’s disease ENSG00000175115 ENSG00000143376 ENSG00000137845 PMC9673319__F8 Finding memo: versatile interactions of the VPS10p-Domain receptors in Alzheimer’s disease ENSG00000100151 ENSG00000142192 ENSG00000143801 ENSG00000281879 PMC22667__F1 Pheromone response pathway in yeast and summary of epistatic interactions with STE4 and STE11 ENSG00000261832 ENSG00000070831 ENSG00000197601 PMC9020878__F12 Huangqin Tang Interference With Colitis Associated Colorectal Cancer Through Regulation of Epithelial Mesenchymal Transition and Cell Cycle ENSG00000135446 ENSG00000168036 PMC9673319__F6 Finding memo: versatile interactions of the VPS10p-Domain receptors in Alzheimer’s disease ENSG00000069329 ENSG00000281879 PMC8533944__F2 Crosstalk between KRAS, SRC and YAP Signaling in Pancreatic Cancer: Interactions Leading to Aggressive Disease and Drug Resistance ENSG00000109321 ENSG00000136997 ENSG00000168267 ENSG00000146648 ENSG00000131023 PMC10740436__F3 Comparative Serum Proteome Profiling of Canine Benign Prostatic Hyperplasia before and after Castration ENSG00000107404 ENSG00000150991 ENSG00000070831 ENSG00000165879 ENSG00000146648 ENSG00000061938 ENSG00000162896 PMC11913433__F8 M6A modification-mediated MTHFD2 upregulation drives tumor-promoting effects via the PEBP1-RAF1/MEK/ERK signaling cascade ENSG00000065911 ENSG00000073792 ENSG00000165819 PMC8492102__F4 Unboxing the molecular modalities of mutagens in cancer ENSG00000175054 ENSG00000183735 ENSG00000164430 ENSG00000125347 PMC3259192__F2 Sphingolipid Signaling and Hematopoietic Malignancies: To the Rheostat and Beyond ENSG00000002330 ENSG00000069482 ENSG00000168610 PMC4389563__F1 Time-resolved metabolic reprograming during pro-inflammatory macrophage polarization ENSG00000180210 ENSG00000136869 ENSG00000262304 PMC6087673__F1 Apoptosis in Acetaminophen Hepatotoxicity ENSG00000168040 ENSG00000084774 ENSG00000026103 PMC8555029__F4 Cellular mechanosignaling in pulmonary arterial hypertension ENSG00000074181 PMC4625494__F1 Tubulin folding cofactor D (TBCD) cooperates with Dscam during neuronal morphogenesis.(A, B) Schemes of wild-type (A) and TBCD mutant (B) projection neurons ENSG00000141556 ENSG00000105254 ENSG00000015285 ENSG00000198125 ENSG00000291561 PMC6747374__F8 Signaling pathways involved in the AVP-dependent myogenic differentiation ENSG00000198793 PMC7648688__F8 Network of potential core targets and signaling pathways in the treatment of IS by AT ENSG00000027075 ENSG00000087245 ENSG00000116044 ENSG00000181104 ENSG00000148344 ENSG00000112715 ENSG00000121879 ENSG00000073756 ENSG00000007171 ENSG00000104368 ENSG00000132170 ENSG00000102977 ENSG00000180210 ENSG00000170890 ENSG00000117525 ENSG00000149968 ENSG00000188257 ENSG00000177606 ENSG00000125538 ENSG00000095303 ENSG00000100985 ENSG00000005381 PMC8126512__F2 Intersection of COVID-19 and cancer: signaling pathways and treatment implications ENSG00000148798 ENSG00000168610 ENSG00000010671 PMC3020075__F1 GPC5 Gene and Its Related Pathways in Lung Cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000179399 PMC9562648__F2 Mitochondrial VDAC1: A Potential Therapeutic Target of Inflammation-Related Diseases and Clinical Opportunities ENSG00000162711 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000163568 ENSG00000125538 PMC8892093__F6 Antroquinonol administration in animal preclinical studies for Alzheimer's disease (AD): A new avenue for modifying progression of AD pathophysiology ENSG00000142192 PMC12178073__F4 Regulatory role of DEAD/H box helicases in the toll like receptor (TLR) signaling pathway ENSG00000174125 ENSG00000109320 ENSG00000163220 ENSG00000173039 ENSG00000174953 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000089737 ENSG00000184216 ENSG00000164342 PMC9207346__F4 Emerging Insight Into the Role of Circadian Clock Gene BMAL1 in Cellular Senescence ENSG00000149311 ENSG00000175054 ENSG00000135446 PMC2834552__F11 Schematic diagram of AGE-induced CTGF expression is shown PMC7590703__F1 Functional and cell number defects in NK cells caused by different PIDs ENSG00000147168 ENSG00000196839 ENSG00000140968 ENSG00000015285 ENSG00000180644 ENSG00000179348 ENSG00000143669 PMC12074830__F5 TLR signaling pathway ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 PMC4317900__F3 Disease-specific mutations in T-cell large granular lymphocytic leukemia and natural killer (NK)/T-cell lymphoma ENSG00000164136 ENSG00000105639 ENSG00000168610 PMC4317900__F1 Disease-specific mutations in B-cell lymphoid neoplasms ENSG00000112576 ENSG00000105369 ENSG00000157764 ENSG00000198793 ENSG00000150455 ENSG00000010671 ENSG00000095585 ENSG00000122882 ENSG00000136997 ENSG00000172936 ENSG00000283060 ENSG00000175104 ENSG00000184216 ENSG00000198286 PMC2633398__F9 An epistatic pathway and genetic model for replication slowing in fission yeast ENSG00000163624 ENSG00000175854 ENSG00000051180 ENSG00000100206 ENSG00000156384 PMC10140952__F4 Selected molecular targets of resveratrol ENSG00000019991 ENSG00000126775 ENSG00000087586 ENSG00000166851 ENSG00000118777 ENSG00000168610 ENSG00000057663 ENSG00000115415 ENSG00000123374 ENSG00000136869 ENSG00000096717 ENSG00000145782 ENSG00000146648 PMC9031669__F2 Key Signaling in Alcohol-Associated Liver Disease: The Role of Bile Acids ENSG00000276559 ENSG00000167910 ENSG00000115271 ENSG00000122787 ENSG00000135929 PMC7763461__F1 Toll-like receptor (TLR) signaling pathways ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000125538 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC8457632__F2 Antiviral Immune Evasion of SARS-CoV-2 ENSG00000101146 ENSG00000115415 ENSG00000100883 ENSG00000153037 ENSG00000110713 PMC6404589__F5 Differential regulation of neurotrophin signaling pathway genes ENSG00000002330 PMC6100584__F1 Mechanism of Hedgehog pathway activation ENSG00000136997 ENSG00000164690 ENSG00000128602 PMC4705542__F5 Schematic summary of the proposed photoneuroendocrine control of VGF expression ENSG00000143320 ENSG00000198576 ENSG00000128564 PMC6100584__F2 Crosstalk of the Hedgehog pathway with other protumorigenic pathways ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000171791 ENSG00000114315 ENSG00000128602 PMC6651373__F3 The molecular mechanism of DAPK1 in AD ENSG00000127445 ENSG00000142192 ENSG00000165795 PMC10474047__F8 Neurod1/4-Ntrk3-Src pathway regulates gonadotrope cell motility during gonadotrope differentiation ENSG00000163629 ENSG00000196396 ENSG00000173406 ENSG00000277363 ENSG00000179295 PMC8040299__F10 Pattern diagram HHT influence miR-18a-3p and AKT/mTOR signaling pathway ENSG00000198793 ENSG00000171791 ENSG00000100985 PMC9746897__F2 Pyroptosis: A new insight of non-small-cell lung cancer treatment ENSG00000278718 ENSG00000162711 ENSG00000111537 ENSG00000167914 ENSG00000145649 ENSG00000189403 ENSG00000064012 ENSG00000164305 ENSG00000147697 ENSG00000073605 PMC10377067__F7 Metabolic Profiles Point Out Metabolic Pathways Pivotal in Two Glioblastoma (GBM) Cell Lines, U251 and U-87MG ENSG00000117054 ENSG00000122971 ENSG00000115419 ENSG00000026103 PMC5214967__F1 Biosynthesis of the lipid-linked oligosaccharide precursor for N-linked glycosylation and known defects in this pathway ENSG00000101901 ENSG00000000419 ENSG00000139133 ENSG00000134910 ENSG00000033011 ENSG00000172269 ENSG00000163933 ENSG00000163527 ENSG00000088035 ENSG00000214160 ENSG00000136908 ENSG00000182858 PMC3830611__F1 Circuitry and biochemical basis for Tuberous Sclerosis symptoms: From Epilepsy to Neurocognitive deficits PMC3420937__F6 PTEN Negatively Regulates MAPK Signaling during Caenorhabditis elegans Vulval Development ENSG00000171105 ENSG00000146648 PMC8617589__F10 Selenoprotein M Promotes Hypothalamic Leptin Signaling and Thioredoxin Antioxidant Activity ENSG00000148346 ENSG00000221869 ENSG00000265972 ENSG00000168610 ENSG00000198832 PMC9200662__F7 Model for the role of the sequential modification of ERA by UFM1 and ubiquitin in the transactivation pathway ENSG00000120686 PMC8016657__F2 Roles of Epac in synaptic plasticity, neurodevelopment, and cell death ENSG00000157764 ENSG00000198793 ENSG00000181467 PMC2999296__F2 Toll-like recepter 4 signaling pathway modified from Wikipedia Commons ENSG00000183735 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC4335664__F3 The crosstalk between the IGF-1 system and estrogens in breast cancer ENSG00000169047 ENSG00000198793 ENSG00000140443 PMC7582192__F5 Targeting N-myristoylation for therapy of B-cell lymphomas ENSG00000105369 ENSG00000143761 ENSG00000007312 ENSG00000186716 PMC5852553__F9 Rac signaling pathway ENSG00000070831 ENSG00000173599 ENSG00000177606 ENSG00000026508 PMC8413680__AF1 LINC00941 promotes glycolysis in pancreatic cancer by modulating the Hippo pathway ENSG00000074800 ENSG00000159399 PMC4859755__F1 Phosphatidylinositol 3-Kinase: A Link Between Inflammation and Pancreatic Cancer ENSG00000274247 ENSG00000164266 ENSG00000001626 ENSG00000122194 PMC6770103__F4 Differentially expressed genes in the neurotrophin signaling pathway between mandarin fish at CG and LG from a transcriptome analysis ENSG00000142192 ENSG00000169291 ENSG00000175104 PMC6585541__F1 Are the mechanisms involved in astrocyte and lymphocyte death during HIV infection similar? ENSG00000162711 ENSG00000121966 PMC6770103__F5 Differentially expressed genes in the cyclic AMP (cAMP) signaling pathway between mandarin fish in the control group (CG) and the learning group (LG) from a transcriptome analysis ENSG00000104899 ENSG00000163914 ENSG00000157017 ENSG00000132170 PMC6021501__F2 Role of apolipoproteins during early steps of hepatitis C virus (HCV) entry ENSG00000130164 ENSG00000110651 ENSG00000146648 PMC2747008__F12 Induction of IFNB and the Innate Antiviral Response in Myeloid Cells Occurs through an IPS-1-Dependent Signal That Does Not Require IRF-3 and IRF-7 ENSG00000183735 ENSG00000105397 ENSG00000115415 ENSG00000177606 ENSG00000131323 ENSG00000175104 ENSG00000142166 PMC7757029__F3 Alternations of signal pathway of MYC in breast cancer tumorigenesis ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000135446 ENSG00000177606 ENSG00000136997 ENSG00000168036 ENSG00000185591 ENSG00000105810 ENSG00000139687 PMC8523029__F1 12(S)-HETE/GPR31 Signaling Pathways ENSG00000120436 ENSG00000163914 PMC6607099__F1 Potential mechanism of Fn in CRC ENSG00000069482 ENSG00000181847 ENSG00000168036 ENSG00000172936 PMC1571066__F2 TGFB superfamily signalling pathway (see text for explanation) ENSG00000170365 ENSG00000137834 PMC6874443__F5 Functional enrichment analysis and construction of PPI network ENSG00000139193 ENSG00000137078 ENSG00000160185 ENSG00000122122 ENSG00000147168 ENSG00000161405 ENSG00000198851 ENSG00000009790 ENSG00000101082 ENSG00000175463 ENSG00000096996 ENSG00000186810 ENSG00000104814 ENSG00000102879 ENSG00000140368 ENSG00000089012 ENSG00000162676 ENSG00000181847 ENSG00000156127 PMC1571066__F5 Model of SMAD7 role in control of blood vessel calibre (see text for explanation) ENSG00000170365 PMC6019445__F1 Schematic describing invariant natural killer T (iNKT) cell development and function in the thymus ENSG00000102962 ENSG00000158473 ENSG00000160224 ENSG00000102970 ENSG00000122877 ENSG00000272398 ENSG00000107485 ENSG00000135605 PMC8344376__F2 SASP regulation ENSG00000159167 ENSG00000149311 ENSG00000141867 ENSG00000105612 ENSG00000285109 ENSG00000198793 PMC3960235__F3 The Anti-Hypercholesterolemic Effect of Low p53 Expression Protects Vascular Endothelial Function in Mice ENSG00000167910 PMC6368838__F4 Identification of gene signature and critical pathway associated with childhood-onset type 2 diabetes ENSG00000105835 ENSG00000177030 ENSG00000132313 ENSG00000179933 ENSG00000123154 ENSG00000197050 ENSG00000084733 ENSG00000099326 ENSG00000109705 PMC9190019__F6 Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation ENSG00000163235 ENSG00000173933 ENSG00000168036 ENSG00000007384 ENSG00000146648 PMC9034917__F9 Network Pharmacology-Based Prediction and Verification of the Potential Targets of Pinoresinol Diglucoside for OA Treatment ENSG00000125538 ENSG00000171791 PMC3293036__F1 The Wnt signaling pathway in cancer cells ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198793 PMC9630943__F3 IL-33/ST2 immunobiology in coronary artery disease: A systematic review and meta-analysis ENSG00000137033 ENSG00000172936 ENSG00000136869 ENSG00000185187 ENSG00000175104 ENSG00000184216 PMC6928633__F3 Constructed metabolic pathway that integrated relative metabolite contents and gene expression for three different sizes (small, medium and large) of beech mushrooms PMC3139189__F1 Intrinsic pathway of apoptosis ENSG00000100290 ENSG00000002330 ENSG00000104081 ENSG00000084774 PMC9274081__F2 Inflammation in Cardiac Remodeling After Acute Myocardial Infarction ENSG00000162711 ENSG00000125538 ENSG00000132693 PMC3139189__F2 B1/Fak/Src integrin signaling, cell survival, and suppression of anoikis ENSG00000002330 ENSG00000291971 ENSG00000010810 ENSG00000104081 PMC3139189__F3 Common pathway of anoikis induction ENSG00000132906 ENSG00000002330 ENSG00000291971 ENSG00000164305 ENSG00000104081 PMC7508434__F5 Diagram for the molecular mechanism ENSG00000145824 ENSG00000168610 PMC3062538__F5 The regulation of IgA class switching ENSG00000105329 ENSG00000145777 ENSG00000162896 PMC6575164__F3 Possible mechanisms of action of targeted polyIC ENSG00000183735 ENSG00000088888 ENSG00000144895 ENSG00000131323 ENSG00000164342 PMC5852553__F4 Phosphatase and tensin homolog (PTEN) signaling pathway ENSG00000002330 ENSG00000110395 PMC11968285__F7 SONFH reveals that BMSC Piezo1 in response to elevated IOP regulates bone vascular homeostasis through CAM-NFAT1 signaling pathway ENSG00000107562 ENSG00000103335 PMC8198713__F12 Novel Characterization of Constipation Phenotypes in ICR Mice Orally Administrated with Polystyrene Microplastics ENSG00000103375 ENSG00000001626 ENSG00000293532 PMC5973372__F1 Hippo信号通路。A：果蝇中的Hippo信号通路；B：哺乳动物中的Hippo信号通路。Hippo signaling pathway ENSG00000126016 ENSG00000186575 ENSG00000157933 ENSG00000078747 ENSG00000163914 ENSG00000113161 ENSG00000026508 ENSG00000139926 ENSG00000143322 ENSG00000139842 ENSG00000150457 ENSG00000131023 PMC4940412__F4 Glycolysis superpathway gene expression profiles ENSG00000143252 ENSG00000074800 ENSG00000073578 ENSG00000117118 PMC9147752__F2 Retinal Glutamate Neurotransmission: From Physiology to Pathophysiological Mechanisms of Retinal Ganglion Cell Degeneration ENSG00000196531 ENSG00000198793 ENSG00000177606 PMC7698326__F1 GWAS of fibrosing disorders ENSG00000167207 ENSG00000105329 ENSG00000161405 ENSG00000163599 ENSG00000169031 ENSG00000168811 ENSG00000057663 ENSG00000159167 ENSG00000084734 ENSG00000137265 ENSG00000269404 ENSG00000117983 ENSG00000169344 ENSG00000109320 ENSG00000197632 ENSG00000153064 ENSG00000107736 ENSG00000177663 ENSG00000096996 ENSG00000182533 ENSG00000138378 ENSG00000106617 ENSG00000226275 ENSG00000069869 ENSG00000160223 ENSG00000164362 ENSG00000070950 ENSG00000142002 ENSG00000184216 ENSG00000136689 ENSG00000137474 ENSG00000168685 PMC9318662__F1 In Silico Approach in the Evaluation of Pro-Inflammatory Potential of Polycyclic Aromatic Hydrocarbons and Volatile Organic Compounds through Binding Affinity to the Human Toll-Like Receptor 4 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC10778111__F3 Non-coding (nc)RNA-regulated signaling pathways involved in gastric cancer invasion ENSG00000070831 ENSG00000134982 ENSG00000198793 ENSG00000163914 ENSG00000146648 PMC9138354__F1 Synergistic Cooperation between TGFB and Hypoxia in Cancer and Fibrosis ENSG00000087245 ENSG00000157500 ENSG00000163914 ENSG00000100985 ENSG00000136044 ENSG00000175104 PMC9354699__F7 Inhibition of KIR2.1 decreases pulmonary artery smooth muscle cell proliferation and migration ENSG00000132646 PMC6579679__F8 Distinct roles of myofibroblast-specific Smad2 and Smad3 signaling in repair and remodeling of the infarcted heart PMC7734100__F2 How coronavirus disrupts signaling pathways (autophagy, ER stress, cytokine storm, and hypoxia) and induces cell death ENSG00000145604 ENSG00000177169 ENSG00000128272 ENSG00000144895 ENSG00000102007 ENSG00000100219 PMC8102340__F1 Project flow chart summarizing analyses and key results ENSG00000135333 ENSG00000070731 ENSG00000122787 ENSG00000081087 ENSG00000137877 ENSG00000134899 ENSG00000169436 ENSG00000074181 ENSG00000069188 ENSG00000172594 ENSG00000179632 ENSG00000291809 ENSG00000150667 ENSG00000100154 ENSG00000031691 ENSG00000174611 ENSG00000253729 PMC4120684__F2 Comparison between recombinant Shh- and EVsShh+-activated pathways modulating angiogenesis and apoptosis in endothelial cells ENSG00000019991 ENSG00000164690 ENSG00000128602 PMC7899295__F3 WNT pathway mutations underlie vitreoretinopathies that have phenotypic overlap with pathologies seen in the DC spectrum diseases ENSG00000162337 ENSG00000106025 ENSG00000168036 PMC2655360__F7 Pathway maps generated using GenMapp depicting increased glycolytic protein expression in differentiated intestinal epithelial cells relative to crypt cells ENSG00000125166 ENSG00000173599 ENSG00000171759 ENSG00000164708 ENSG00000078098 ENSG00000136872 ENSG00000131828 ENSG00000091140 ENSG00000113494 ENSG00000152556 PMC4202134__F7 Selenocysteine derivative overcomes TRAIL resistance in melanoma cells: evidence for ROS-dependent synergism and signaling crosstalk ENSG00000002330 ENSG00000168040 ENSG00000026103 PMC8815749__F5 Bioenergetic Evolution Explains Prevalence of Low Nephron Number at Birth: Risk Factor for CKD ENSG00000177169 ENSG00000134086 ENSG00000198793 PMC6981291__F1 Crosstalk between Nrf2 signaling and Mitochondrial function in Parkinson’s Disease ENSG00000065833 ENSG00000182511 ENSG00000074800 ENSG00000023909 ENSG00000159399 ENSG00000105227 PMC5080294__F2 Proposed model for the targeting of NRAS-mutant melanoma by ERB ligands ENSG00000112576 ENSG00000197299 PMC3196718__F4 Network of upregulated genes in C2C12 cells treated with rhBMP2 and rhBMP7 using the STRING 9.0 pathway analyzer ENSG00000154342 ENSG00000281324 ENSG00000002330 ENSG00000030582 ENSG00000174332 ENSG00000168036 ENSG00000130159 ENSG00000276920 ENSG00000184481 ENSG00000166033 ENSG00000170365 ENSG00000133110 ENSG00000100592 ENSG00000107249 ENSG00000083444 ENSG00000283060 ENSG00000096717 ENSG00000107821 ENSG00000125968 PMC9350078__F3 NK cell dysfunction is linked with disease severity in SARS‐CoV‐2 patients ENSG00000150782 ENSG00000174059 PMC6668540__F2 TLR signaling pathways ENSG00000175104 ENSG00000276561 PMC2727911__F1 Activation pathways of the complement system and complement regulatory proteins ENSG00000039537 ENSG00000009724 ENSG00000291559 ENSG00000166278 ENSG00000182326 ENSG00000236625 PMC3741439__F1 The catecholamine biosynthetic pathway ENSG00000141744 ENSG00000171759 PMC2268064__F2 Signalling pathways leading to the phosphorylation and inhibition of glycogen synthase kinase 3 (GSK3) ENSG00000138798 ENSG00000198793 PMC4017002__F8 PPARB/D promotes HRAS-induced senescence by potentiating p-ERK and repressing p-AKT ENSG00000140992 PMC9621439__F2 Mammalian and basal innate immune signaling via NFKB ENSG00000164430 ENSG00000276561 PMC2268064__F3 Regulation of the transcriptional co-regulator Beta-catenin ENSG00000138795 ENSG00000134982 ENSG00000168036 PMC5825873__F2 Pathways that regulate mTORC1 and mTORC2 signaling ENSG00000146648 PMC3075080__F3 Proposed ACE2/ANG-(1–7)/Mas signaling pathways in the central nervous system ENSG00000096395 ENSG00000130234 ENSG00000168610 PMC6164903__F3 Innate immune response to baculovirus infection in non-immune cells ENSG00000183735 ENSG00000164430 PMC6164903__F2 Induction of innate immune response by viral infection ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC11172187__F1 Gliogenic switch during brain development ENSG00000125398 ENSG00000131095 ENSG00000114315 ENSG00000162599 PMC4961994__F2 Summary of TGFB signaling during EMT ENSG00000125740 ENSG00000169554 ENSG00000122691 ENSG00000288335 PMC11703747__F2 Cellular metabolic pathway involving GOT1 ENSG00000049768 ENSG00000096717 PMC6337314__F2 TREM2 activation and downstream signaling ENSG00000011600 ENSG00000213658 ENSG00000137845 PMC10534826__F2 Impact of Opioids on Cellular Metabolism: Implications for Metabolic Pathways Involved in Cancer ENSG00000105664 ENSG00000173599 ENSG00000115419 ENSG00000062485 PMC6135256__F4 The effects of NBUVB on the bulge and epidermis of human vitiligo skin during repigmentation ENSG00000124216 ENSG00000041982 ENSG00000125398 ENSG00000168036 ENSG00000104332 ENSG00000155760 ENSG00000121742 ENSG00000137801 PMC4603759__F6 Flux balance analysis predicts essential genes in clear cell renal cell carcinoma metabolism ENSG00000048392 ENSG00000167325 ENSG00000171848 ENSG00000186281 PMC6631457__F8 Schematic showing that exosomes carrying miRNAs promote NDV infection ENSG00000088888 ENSG00000115415 ENSG00000276561 PMC10377020__F1 ER Stress, the Unfolded Protein Response and Osteoclastogenesis: A Review ENSG00000128272 ENSG00000100219 ENSG00000079999 PMC10377020__F2 ER Stress, the Unfolded Protein Response and Osteoclastogenesis: A Review ENSG00000170909 ENSG00000147614 ENSG00000101307 ENSG00000178573 ENSG00000291971 ENSG00000164935 ENSG00000100985 ENSG00000175104 ENSG00000131196 ENSG00000079999 ENSG00000143387 PMC3320973__F8 Wnt signaling regulation induced by cell surface HSPG desulfation during dentinogenesis ENSG00000152591 ENSG00000196562 ENSG00000137573 PMC7369957__F1 Canonical Wnt pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC5902714__F8 Summarized scheme for the regulation of spexin on bile acid pathway ENSG00000128310 ENSG00000182687 ENSG00000276559 ENSG00000180432 ENSG00000115271 ENSG00000135929 PMC12122839__F2 Generation and metabolism of sulfur-containing biomolecules ENSG00000198793 PMC4102744__F1 Cytoplasmic/traditional and nuclear modes of the epidermal growth factor receptor (EGFR) signalling pathway ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC12122839__F3 Sulfide signaling pathway ENSG00000134982 ENSG00000168036 ENSG00000079999 PMC4632082__F6 CD44 deficiency inhibits unloading-induced cortical bone loss through downregulation of osteoclast activity ENSG00000291971 ENSG00000026508 ENSG00000175104 ENSG00000131196 PMC6647228__F2 Schematic presentation depicting the energy metabolic pathways through which AMPK controls the activation of MDSCs ENSG00000135218 ENSG00000116044 ENSG00000198793 ENSG00000168610 PMC6924059__F4 ARHGAP9-mediated regulation of the MAPK signaling pathway in BC ENSG00000138798 ENSG00000146648 PMC7801920__F2 Related molecules, genes, signaling pathways and biological function in HCC of miR-200 family ENSG00000168283 ENSG00000169554 ENSG00000163914 ENSG00000162521 PMC4445742__F4 Model depicting PPP1R12A/PP1cD in the insulin signaling pathway ENSG00000169047 PMC4276281__F2 Schematic of the major pathways of serine metabolism in a mammalian liver ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC5122694__F3 Canonical pathways by IPA: antigen presentation pathway in the NC vs ENSG00000111537 PMC4927194__F2 Diverse extracellular signaling pathways are regulated by A disintegrin and metalloproteinase (ADAM)-mediated shedding events ENSG00000128917 ENSG00000109321 ENSG00000163207 ENSG00000163235 ENSG00000124882 ENSG00000113070 ENSG00000138798 ENSG00000026508 ENSG00000162692 ENSG00000137845 PMC3240717__F9 Pro-inflammatory Cytokine/Chemokine Production and Breast Tumor Invasion ENSG00000125538 ENSG00000026508 ENSG00000172936 PMC6942368__F7 Role of liraglutide in regulating hCMSC paracrine and SPC expression ENSG00000070193 ENSG00000168036 ENSG00000196628 PMC6558915__F10 Schematic presentation of the anti-TNBC mechanism of Ilamycin C ENSG00000143799 ENSG00000087245 ENSG00000100985 ENSG00000168610 PMC5122694__F1 IPA Canonical Pathway analysis showing the interferon signaling pathway across the NC vs ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000157601 ENSG00000230034 PMC5122694__F2 Canonical pathways by IPA: antigen presentation pathway in the NC vs ENSG00000111537 ENSG00000163631 PMC2893543__F4 Schematic overview of costimulatory receptors and their ligands ENSG00000139193 PMC8961590__F1 Posttranscriptional Regulation of Insulin Resistance: Implications for Metabolic Diseases ENSG00000131914 ENSG00000171105 ENSG00000165119 ENSG00000198793 ENSG00000169047 ENSG00000128191 ENSG00000100320 ENSG00000113360 PMC10522861__F7 Analysis of the response mechanisms of Pinellia ternata to terahertz wave stresses using transcriptome and metabolic data ENSG00000110934 ENSG00000221818 ENSG00000140416 PMC5007826__F6 Working model of PRL-3 involvement in TNF-R1 pleiotropy ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC6380503__F1 Metabolites as regulators of insulin sensitivity and metabolism ENSG00000169047 ENSG00000173599 ENSG00000172936 ENSG00000136869 PMC5374731__F2 Schematic summary of genetic abnormalities in ATL cells ENSG00000122566 ENSG00000030419 ENSG00000078900 ENSG00000148400 ENSG00000137265 ENSG00000197943 ENSG00000107485 ENSG00000124181 ENSG00000168610 ENSG00000174611 ENSG00000198286 ENSG00000169508 PMC8416371__F8 Based on Network Pharmacology to Explore the Potential Bioactive Compounds and Mechanisms of Zuojin Pill for the Treatment of Ulcerative Colitis ENSG00000002330 ENSG00000148798 ENSG00000182326 ENSG00000132341 PMC8416371__F9 Based on Network Pharmacology to Explore the Potential Bioactive Compounds and Mechanisms of Zuojin Pill for the Treatment of Ulcerative Colitis ENSG00000142192 ENSG00000102871 ENSG00000135605 PMC8334720__F1 Interplay Between mTOR and Hippo Signaling in the Ovary: Clinical Choice Guidance Between Different Gonadotropin Preparations for Better IVF ENSG00000118971 PMC4316815__F2 Regulation by zinc of the ERK1/2 signaling cascade ENSG00000183840 PMC6927014__F6 Protein–protein interaction and pathways analysis ENSG00000275618 ENSG00000058085 ENSG00000110799 ENSG00000102871 ENSG00000091409 ENSG00000187266 ENSG00000137801 ENSG00000095585 ENSG00000103479 ENSG00000213658 ENSG00000136997 ENSG00000125538 ENSG00000139626 ENSG00000198286 ENSG00000259207 ENSG00000170027 ENSG00000119535 ENSG00000111816 ENSG00000149311 ENSG00000226275 ENSG00000186716 ENSG00000131323 ENSG00000162692 ENSG00000124253 ENSG00000121060 ENSG00000168685 PMC5443811__F8 Illustration of the chondroprotective effects of sUA and the mechanisms underlying these effects ENSG00000125538 ENSG00000158859 PMC7802442__F4 Case of UDP-Galactose 4′-Epimerase Deficiency Associated with Dyshematopoiesis and Atrioventricular Valve Malformations: An Exceptional Clinical Phenotype Explained by Altered N-Glycosylation with Relative Preservation of the Leloir Pathway ENSG00000069482 PMC6570467__F6 Prioritization of metabolic genes as novel therapeutic targets in estrogen-receptor negative breast tumors using multi-omics data and text mining ENSG00000109814 ENSG00000067064 ENSG00000151726 ENSG00000105835 ENSG00000198380 ENSG00000134824 ENSG00000141744 ENSG00000099810 PMC3343040__F6 Environmentally Induced Epigenetic Transgenerational Inheritance of Ovarian Disease ENSG00000197043 ENSG00000151726 ENSG00000107562 ENSG00000105835 ENSG00000280962 ENSG00000181104 ENSG00000197746 ENSG00000186480 ENSG00000113161 ENSG00000143226 ENSG00000109854 ENSG00000065833 ENSG00000130402 ENSG00000189403 ENSG00000177666 ENSG00000189067 ENSG00000135929 ENSG00000089327 ENSG00000125166 ENSG00000123643 ENSG00000087245 ENSG00000130783 ENSG00000106333 ENSG00000141424 ENSG00000112964 ENSG00000205220 ENSG00000130304 ENSG00000138378 ENSG00000115884 ENSG00000173372 ENSG00000001630 ENSG00000149809 ENSG00000161533 ENSG00000175899 ENSG00000114315 ENSG00000079435 ENSG00000198911 PMC3343040__F7 Environmentally Induced Epigenetic Transgenerational Inheritance of Ovarian Disease ENSG00000087245 ENSG00000107562 ENSG00000105835 ENSG00000108679 ENSG00000181104 ENSG00000113161 ENSG00000166073 ENSG00000120675 ENSG00000130402 ENSG00000079435 ENSG00000171033 ENSG00000198625 PMC3763401__F1 Crosstalk between COX-2 and EGF signaling pathway in CRC ENSG00000138798 ENSG00000126353 ENSG00000146648 PMC9698582__F11 G Protein-Coupled Receptor 37L1 Modulates Epigenetic Changes in Human Renal Proximal Tubule Cells ENSG00000170075 ENSG00000198793 ENSG00000253729 PMC4331529__F8 miR-30 Family microRNAs Regulate Myogenic Differentiation and Provide Negative Feedback on the microRNA Pathway ENSG00000090905 ENSG00000019549 ENSG00000108604 PMC5715847__F1 B‐Catenin‐dependent pathway ENSG00000134982 ENSG00000168036 PMC5715847__F2 Wnt/PCP pathway ENSG00000100592 ENSG00000177606 ENSG00000067900 PMC6824464__F1 Glycolysis and pentose phosphate pathway ENSG00000152556 PMC8039141__F2 The different mechanisms involved in Senescence Associated Secretory Phenotype (SASP) regulation ENSG00000149311 ENSG00000141867 ENSG00000164430 ENSG00000172216 ENSG00000285109 ENSG00000056972 ENSG00000198793 ENSG00000175104 ENSG00000115594 PMC9203716__F3 Case Report: Extensive Tumor Profiling in Primary Neuroendocrine Breast Cancer Cases as a Role Model for Personalized Treatment in Rare and Aggressive Cancer Types ENSG00000101751 ENSG00000118515 ENSG00000171791 PMC9115384__F3 Recent Advances of Autophagy in Non-Small Cell Lung Cancer: From Basic Mechanisms to Clinical Application ENSG00000136603 ENSG00000169245 PMC9115384__F1 Recent Advances of Autophagy in Non-Small Cell Lung Cancer: From Basic Mechanisms to Clinical Application ENSG00000188554 ENSG00000198382 ENSG00000083290 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 ENSG00000136874 PMC5715847__F3 Wnt‐cGMP/Ca2+pathway ENSG00000087095 ENSG00000070831 ENSG00000168036 PMC8080617__F3 Active D-secretase is the trigger for both AD and PD ENSG00000135250 PMC7914561__F1 Methionine cycle PMC9312434__F3 Src Family Kinases: A Potential Therapeutic Target for Acute Kidney Injury ENSG00000291971 ENSG00000168610 PMC3615463__F1 Phosphoinositide 3-Kinase Inhibition in Chronic Lymphocytic Leukemia ENSG00000186716 ENSG00000198793 ENSG00000010671 PMC3799998__F1 Antimicrobial Autophagy: A Conserved Innate Immune Response in Drosophila ENSG00000177169 ENSG00000110497 ENSG00000152348 ENSG00000123395 ENSG00000198382 ENSG00000083290 ENSG00000126775 ENSG00000196455 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC9622871__F8 Drug transporters OAT1 and OAT3 have specific effects on multiple organs and gut microbiome as revealed by contextualized metabolic network reconstructions ENSG00000197713 ENSG00000198125 PMC7894463__F2 Lumped network of the carbon metabolism of Rhodobacter sphaeroides, including pathways for substrate uptake and product formation ENSG00000039537 ENSG00000172005 ENSG00000197429 ENSG00000166278 ENSG00000062485 PMC5306179__F1 Canonical and alternative pathways for NFKB activation ENSG00000104856 ENSG00000112977 ENSG00000186716 ENSG00000162924 PMC6650903__F4 Schematic plot of significantly differentially expressed genes involved in GA metabolism and signaling under CK, CCC, and PBZ treatments in roots and shoots ENSG00000140451 PMC7760945__F3 Intra-articular (IA) delivery of cargo-loaded nanoparticles for the treatment of OA ENSG00000150782 ENSG00000125538 PMC9465182__F1 Dysregulated lipolysis and lipophagy in lipid droplets of macrophages from high fat diet‐fed obese mice ENSG00000166819 ENSG00000187796 PMC2490739__F8 Scheme summarizing the differential effect of PARP-1 inhibition versus silencing on SSB repair via the BER pathway ENSG00000132646 ENSG00000116096 ENSG00000138385 PMC9184651__F4 Signaling pathways of chronic kidney diseases, implications for therapeutics ENSG00000086991 ENSG00000168036 ENSG00000121966 PMC3009741__F3 Bioinformatics Analysis of Macrophages Exposed to Porphyromonas gingivalis: Implications in Acute vs. Chronic Infections ENSG00000108691 ENSG00000167207 ENSG00000172936 ENSG00000136869 ENSG00000106100 PMC6905557__F6 Chemogenomic profiling to understand the antifungal action of a bioactive aurone compound ENSG00000070831 ENSG00000142751 ENSG00000141977 ENSG00000081277 ENSG00000073111 ENSG00000035928 PMC4530997__F1 Selective delivery of ITCs to bladder on oral consumption and modulation of cellular targets by ITCs in BC cells and tissues ENSG00000146648 PMC7405402__F2 Cell cycle of SARS‐CoV‐2 in the host cells ENSG00000069482 ENSG00000130234 ENSG00000184012 ENSG00000214285 PMC5869526__F1 Interferon-like antiviral response ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000160710 ENSG00000172936 PMC6476530__F1 Strategies in regulating glioblastoma signaling pathways and anti-invasion therapy ENSG00000198793 ENSG00000135932 ENSG00000129355 ENSG00000166851 PMC10313451__F6 Imipramine mechanism of action in breast cancers ENSG00000157554 ENSG00000012048 ENSG00000175054 ENSG00000135446 PMC3315209__F6 Speculative model for the role of the Hippo pathway in germ cell tumorigenesis and reprogramming ENSG00000150457 ENSG00000256453 PMC3494597__F1 Inactivation of the Cullin (CUL)-RING E3 ligase by the NEDD8-activating enzyme inhibitor MLN4924 triggers protective autophagy in cancer cells ENSG00000198793 ENSG00000159593 ENSG00000155792 ENSG00000057663 PMC5877528__F6 The AR induction pathway in ‘T337’ basal cuttings ENSG00000120500 ENSG00000120885 ENSG00000047597 PMC8418153__F2 Ferroptosis: A Trigger of Proinflammatory State Progression to Immunogenicity in Necroinflammatory Disease ENSG00000168003 ENSG00000167468 ENSG00000136381 PMC9458733__F4 Metabolomic alterations in the blood plasma of older adults with mild cognitive impairment and Alzheimer’s disease (from the Nakayama Study) ENSG00000081181 ENSG00000088826 ENSG00000143450 ENSG00000104904 ENSG00000142920 ENSG00000180304 ENSG00000118520 ENSG00000036473 ENSG00000116649 ENSG00000102172 PMC9523169__F3 Iron dyshomeostasis and ferroptosis in Alzheimer’s disease: Molecular mechanisms of cell death and novel therapeutic drugs and targets for AD ENSG00000167996 PMC3978582__F4 Functional gene networks identified using Ingenuity Pathway Analysis (IPA) from differentially expressed genes between the control and treated discs ENSG00000136158 ENSG00000138821 ENSG00000291560 ENSG00000110395 ENSG00000198053 ENSG00000067057 ENSG00000157227 ENSG00000136153 ENSG00000136213 ENSG00000213145 ENSG00000159399 PMC3978582__F5 Functional gene networks identified using Ingenuity Pathway Analysis (IPA) from differentially expressed genes between the control and experimental discs ENSG00000162594 ENSG00000109320 ENSG00000186716 ENSG00000173039 ENSG00000106624 ENSG00000106100 PMC3065471__F3 Discovery of Molecular Mechanisms of Traditional Chinese Medicinal Formula Si-Wu-Tang Using Gene Expression Microarray and Connectivity Map ENSG00000147162 ENSG00000178573 PMC8669610__F4 TGFB Signaling and Resistance to Cancer Therapy ENSG00000108691 ENSG00000049768 PMC6304490__F2 Examples of in vitro molecular action of quercetin (Q) in cited cellular experiments ENSG00000163235 ENSG00000177606 ENSG00000015285 PMC7164363__F7 EphB4, TNFR2 and ERK/MAPK signaling pathways ENSG00000131323 ENSG00000127191 PMC8665957__F1 Review: the effect of light on the key pigment compounds of photosensitive etiolated tea plant ENSG00000080819 ENSG00000126088 ENSG00000188690 ENSG00000127948 PMC3978582__F3 Functional gene networks identified using Ingenuity Pathway Analysis (IPA) from differentially expressed genes between the control and treated discs ENSG00000173221 ENSG00000213949 ENSG00000142178 ENSG00000026508 ENSG00000116717 ENSG00000092820 PMC8669610__F1 TGFB Signaling and Resistance to Cancer Therapy ENSG00000198793 ENSG00000163914 ENSG00000175104 ENSG00000076604 PMC8669610__F3 TGFB Signaling and Resistance to Cancer Therapy ENSG00000189403 ENSG00000287542 ENSG00000118777 ENSG00000273820 PMC4529925__F3 Model of SAM68 interaction with pre-mRNAs and splicing regulation ENSG00000291971 ENSG00000198793 ENSG00000026508 PMC4940389__F1 Regulation of HH and Wnt/Beta-catenin signaling by 1,25(OH)2D/VDR and calcium/Casr ENSG00000205221 ENSG00000168036 ENSG00000164690 ENSG00000128602 ENSG00000186104 ENSG00000135929 PMC7006399__F6 Gene network analysis and interaction subnetworks ENSG00000141349 ENSG00000164904 ENSG00000114349 ENSG00000157764 ENSG00000163558 ENSG00000198793 ENSG00000163914 ENSG00000127022 ENSG00000132915 ENSG00000124253 PMC6400144__F2 Regulation of the C-type lectin receptor signalling pathway by curdlan and MacroGard® ENSG00000104856 ENSG00000108691 ENSG00000197272 ENSG00000164399 ENSG00000083799 PMC4632638__F2 Ibrutinib: a first in class covalent inhibitor of Bruton’s tyrosine kinase ENSG00000105369 ENSG00000007312 ENSG00000172936 ENSG00000010671 ENSG00000198286 PMC5987014__F2 Sclerostin and the Wnt/Beta-catenin signalling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000168036 PMC4903900__F1 Epigenetic modulation of gene expression governs the brain’s response to injury ENSG00000198901 ENSG00000230797 ENSG00000096717 PMC7014054__F15 PtNPs change transcriptional networks ENSG00000128272 ENSG00000178573 ENSG00000130522 ENSG00000177606 ENSG00000122877 ENSG00000162772 ENSG00000157514 PMC321618__F7 Statins and bacterial infection: model illustrating the effects of statins on S. enterica serovar Typhimurium infection ENSG00000163914 ENSG00000122194 PMC1664665__F2 Regulation of the axon cytoskeleton by PI3K signalling ENSG00000070831 ENSG00000134982 ENSG00000163914 PMC1664665__F3 ECM-integrin signalling coordinates with growth factor signalling to regulate efficient axon growth ENSG00000070831 PMC3018769__F8 Composite figure from all time points of microarray data showing apoptotic pathways in HepG2 cells when exposed to PCB-153 (70μM) and PCB-77 (70μM) ENSG00000105329 ENSG00000288335 ENSG00000265972 ENSG00000171791 ENSG00000140465 ENSG00000164305 ENSG00000106546 ENSG00000077150 ENSG00000125144 ENSG00000177606 ENSG00000136997 ENSG00000164400 ENSG00000064012 ENSG00000171885 PMC7004311__F1 One-carbon metabolism ENSG00000214435 ENSG00000291507 ENSG00000173599 ENSG00000116984 ENSG00000133027 PMC4214059__F1 A causal model specifying how genetic variation increases the susceptibility to clinical disease through smoking and alternate pathways () ENSG00000117971 ENSG00000080644 PMC3344904__F1 High Throughput Screening for Small Molecule Enhancers of the Interferon Signaling Pathway to Drive Next-Generation Antiviral Drug Discovery ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC5333035__F5 Fibroblast growth factor-4 (FGF4) signal transduction pathway governs trophoblast proliferation and differentiation ENSG00000134982 ENSG00000112312 PMC3936609__F6 Redox-Mediated and Ionizing-Radiation-Induced Inflammatory Mediators in Prostate Cancer Development and Treatment PMC3936609__F7 Redox-Mediated and Ionizing-Radiation-Induced Inflammatory Mediators in Prostate Cancer Development and Treatment ENSG00000105329 PMC3515920__F1 Retinoid refractoriness due to phosphorylation of retinoid X receptor alpha (RXR A), and its restoration by acyclic retinoid (ACR) in liver carcinogenesis ENSG00000291368 PMC6274717__F2 IL-6 signal transduction and modes of the IL-6 receptor system ENSG00000196843 ENSG00000115415 ENSG00000168610 PMC6152498__F2 Targeting the cell cycle in breast cancer ENSG00000134982 ENSG00000135446 ENSG00000198793 ENSG00000136997 ENSG00000123374 ENSG00000142731 ENSG00000105810 ENSG00000077782 ENSG00000112742 PMC3145607__F5 Ingenuity Pathway Analysis (IPA) on genes modulated by BaP in G1-enriched MCF7 cell cultures ENSG00000111057 ENSG00000163291 ENSG00000146247 ENSG00000138386 ENSG00000091879 ENSG00000167034 ENSG00000087460 ENSG00000105894 ENSG00000108578 ENSG00000066468 ENSG00000260027 ENSG00000128272 ENSG00000177606 ENSG00000177519 ENSG00000288185 ENSG00000177425 PMC12244502__F7 Mechanism by which NEDD4L prevents colorectal cancer liver metastasis ENSG00000198793 PMC3145607__F6 Ingenuity Pathway Analysis (IPA) on genes modulated by BaP in S-enriched MCF-7 cell cultures ENSG00000146376 ENSG00000185022 ENSG00000116044 ENSG00000165891 ENSG00000169862 ENSG00000159388 ENSG00000133401 ENSG00000292058 ENSG00000130283 ENSG00000162772 ENSG00000154447 ENSG00000087460 ENSG00000281614 ENSG00000144283 ENSG00000177606 ENSG00000163993 PMC3145607__F7 Ingenuity Pathway Analysis (IPA) on genes modulated by BaP in G2/M-enriched MCF-7 cell cultures ENSG00000284774 ENSG00000140386 ENSG00000181163 ENSG00000116044 ENSG00000125107 ENSG00000156885 ENSG00000132357 ENSG00000265972 ENSG00000154447 ENSG00000135698 ENSG00000131828 ENSG00000149679 ENSG00000079156 ENSG00000105664 ENSG00000082175 ENSG00000154065 ENSG00000104320 ENSG00000158321 ENSG00000170430 ENSG00000291761 ENSG00000116030 ENSG00000168237 ENSG00000091140 ENSG00000169567 PMC3120109__F4 Schematic illustrating that AMPH indirectly stimulates dopamine (DA), glutamate (glu) and BDNF (B) release and stimulation of D1 dopamine, glutamate, and TrkB receptors, respectively, in the striatum ENSG00000078053 ENSG00000117152 PMC4013419__F1 Major components of Sonic hedgehog (Shh) signaling pathway ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC10759521__F9 DCAF13 inhibits the p53 signaling pathway by promoting p53 ubiquitination modification in lung adenocarcinoma ENSG00000100387 ENSG00000167986 ENSG00000139842 ENSG00000124762 ENSG00000164934 ENSG00000026103 PMC8745051__F2 ATM: Functions of ATM Kinase and Its Relevance to Hereditary Tumors ENSG00000188486 ENSG00000012048 ENSG00000123374 PMC8060181__F1 Osteoblast role in the pathogenesis of rheumatoid arthritis ENSG00000178860 ENSG00000152785 ENSG00000104332 PMC4238355__F7 Model for roles of microRNAs during the reprogramming process PMC11826472__F2 After PNI, several cellular changes are observed in the spinal cord, the injury site, and target organs ENSG00000184371 ENSG00000131095 PMC5315629__F3 Post-excision Events in Human Nucleotide Excision Repair ENSG00000132646 ENSG00000070950 ENSG00000122008 PMC6881331__F7 Molecular mechanisms of p53 loss of heterozygosity in breast cancer in response to DNA damage ENSG00000284774 ENSG00000198793 PMC3799205__F1 The leptin-induced pathways ENSG00000198793 ENSG00000168610 PMC11125855__F1 Intracellular DNA sensors involved in the activation of IFN signaling and the NFKB pathway ENSG00000122566 ENSG00000183735 ENSG00000239732 ENSG00000088888 ENSG00000070495 ENSG00000174953 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC1986651__F1 Regulation of cell proliferation and cell death by PKCE ENSG00000002330 ENSG00000005882 PMC2546905__F4 Predicted targets of miR-100 and miR-101 in the 3′-UTR of members of the mTOR pathway ENSG00000198793 ENSG00000164327 PMC11125855__F3 Inhibition of DNA-sensing pathways by KSHV viral proteins ENSG00000164430 ENSG00000187796 ENSG00000163568 ENSG00000163565 ENSG00000276561 PMC3572136__F8 Novel Pancreatic Endocrine Maturation Pathways Identified by Genomic Profiling and Causal Reasoning ENSG00000157764 ENSG00000109321 ENSG00000131747 ENSG00000117139 ENSG00000087586 ENSG00000091879 ENSG00000168610 ENSG00000122859 ENSG00000124762 ENSG00000069482 ENSG00000292234 ENSG00000198176 ENSG00000115415 ENSG00000111653 ENSG00000139687 ENSG00000282899 ENSG00000125968 PMC9213050__F7 TLR2-mediated NFKB signaling pathway is involved in PPV1-induced apoptosis in PK-15 cells ENSG00000172936 ENSG00000150455 ENSG00000175104 PMC3343650__F5 Three major signaling pathways are altered in prostate cancers ENSG00000145604 ENSG00000157554 ENSG00000147437 ENSG00000119508 ENSG00000089685 ENSG00000138798 ENSG00000169047 ENSG00000105810 ENSG00000139687 ENSG00000178568 ENSG00000160691 PMC5732761__F8 Reversion of resistance to oxaliplatin by inhibition of p38 MAPK in colorectal cancer cell lines: involvement of the calpain / Nox1 pathway ENSG00000291971 ENSG00000188747 PMC5431827__F8 Proposed mechanism by which HBV hijacks IFN/JAK/STAT pathway via activating SOCS2 to facilitate immune evasion and viral infection ENSG00000120833 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC4174315__F7 Mechanistic model depicting the factor association of DDB2 and XPC with ATR and ATM, influencing the DDR pathway in response to UV damage ENSG00000149311 ENSG00000175054 ENSG00000136936 PMC8126717__F2 Escape From Treatment; the Different Faces of Leukemic Stem Cells and Therapy Resistance in Acute Myeloid Leukemia ENSG00000178860 ENSG00000141867 ENSG00000107562 ENSG00000135218 ENSG00000128272 ENSG00000144895 ENSG00000136997 ENSG00000164399 ENSG00000026508 ENSG00000171791 ENSG00000162692 ENSG00000121966 PMC7139330__F1 p38 MAPK activation ENSG00000291603 PMC4064789__F8 The Ron receptor tyrosine kinase activates c-Abl to promote cell proliferation through tyrosine phosphorylation of PCNA in breast cancer ENSG00000138798 ENSG00000132646 ENSG00000146648 PMC6685136__F2 Wnt/Beta-cat signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000133067 ENSG00000183579 ENSG00000108375 PMC5919976__F4 Proposed integrated model of BTN3A1 modifications induced by phosphoantigens and leading to the antigenic activation of VG9VD2 T lymphocytes ENSG00000143878 ENSG00000118898 PMC10708146__F2 GSDMD-mediated pyroptosis in DCM ENSG00000278718 ENSG00000145388 ENSG00000162711 ENSG00000164430 ENSG00000163568 ENSG00000184634 ENSG00000172936 ENSG00000136869 ENSG00000142082 PMC7196244__F6 An illustration of how EVO exerts anticancer activity in osteosarcoma cells through the suppressing Wnt/Beta-catenin signaling pathway ENSG00000134982 ENSG00000170558 ENSG00000168036 PMC2856263__F6 Signaling pathways activated by DMXAA ENSG00000183735 ENSG00000167207 ENSG00000106100 PMC9244849__F4 Disintegrin and metalloproteinase domain 17-epidermal growth factor receptor signaling contributes to oral cancer pain ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000104894 PMC6942807__F2 NRF2-mediated pathway of glutathione synthesis ENSG00000168003 ENSG00000151012 ENSG00000023909 ENSG00000105227 PMC5493720__F2 Changes in the methylation state of parentally imprinted genes lead to attenuation of GH/INS/IGF signaling in VSELs PMC9647096__F2 Regulatory pathway and possible targets of ferroptosis in HCC ENSG00000179148 ENSG00000151012 ENSG00000100577 ENSG00000074219 ENSG00000104064 ENSG00000168003 ENSG00000114770 ENSG00000128272 ENSG00000125144 ENSG00000167996 ENSG00000122873 ENSG00000146648 ENSG00000071626 ENSG00000126432 PMC6515024__F1 Bone morphogenetic protein (BMP) signaling pathway and inhibition by Noggin ENSG00000170365 PMC11982459__F3 Hormonal regulation of the UPR by ABA, JA, and SA PMC4675542__F2 Variants of the Coagulation and Inflammation Genes Are Replicably Associated with Myocardial Infarction and Epistatically Interact in Russians ENSG00000159128 ENSG00000111537 ENSG00000095303 ENSG00000027697 ENSG00000005381 ENSG00000125347 ENSG00000124212 ENSG00000073756 PMC7729528__F1 One‐carbon metabolic pathway ENSG00000100714 ENSG00000124275 ENSG00000185339 ENSG00000116984 PMC3689245__F7 Proposed mechanism for MTX-induced melanosome transport in melanoma ENSG00000205629 PMC8554863__F11 CXCR5 down-regulation alleviates cognitive dysfunction in a mouse model of sepsis-associated encephalopathy: potential role of microglial autophagy and the p38MAPK/NFKB/STAT3 signaling pathway ENSG00000168610 ENSG00000057663 PMC7974894__F7 Identification of Prognosis-related Hub RNA Binding Proteins Function through Regulating Metabolic Processes in Tongue Cancer ENSG00000049768 ENSG00000152556 PMC11649390__F2 Wnt signaling pathways ENSG00000177606 ENSG00000168036 PMC8523516__F1 Translational Regulation in Hepatocellular Carcinogenesis PMC6917511__F2 Flow chart of the RHPCG database ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC6664910__F10 Schematic diagram of LIM kinase-dependent inhibition of n-cofilin activity by Reelin ENSG00000198793 ENSG00000173406 PMC11682641__F2 BCR signalling and associated pathways network, genetic resistance mechanisms and pathway adaptive resistance mechanisms to targeted therapies in CLL ENSG00000177455 ENSG00000095585 ENSG00000105369 ENSG00000136997 ENSG00000185483 ENSG00000172936 ENSG00000184216 ENSG00000010671 PMC11682641__F3 Detailed overview of chronic lymphocytic leukaemia's genetic landscape in the context of signalling network ENSG00000023445 ENSG00000162613 ENSG00000110330 ENSG00000148400 ENSG00000171791 ENSG00000127191 ENSG00000010671 ENSG00000095585 ENSG00000149311 ENSG00000115524 ENSG00000172936 ENSG00000131323 ENSG00000184216 PMC5359278__F1 Schematic diagram showing the mechanism of action of NSAIDs like aspirin in inhibiting the metabolism of arachidonic acid by blockade of the cyclooxygenases (COX) pathway and the prostaglandins (PG) synthase pathway, thus suppressing PGs synthesis PMC6472684__F2 Signaling downstream of the IL-2 receptor (IL-2R): (a) Janus kinase-signal transducer and activator of transcription (JAK-STAT) signal transduction ENSG00000136997 ENSG00000103257 ENSG00000105639 ENSG00000160691 PMC3853752__F3 Co-expression network of 106 genes associated to the FA metabolism in P ENSG00000185591 ENSG00000138356 PMC6562400__F1 Acquisition of cysteine from extracellular cystine through xCT and de novo production of cysteine through the transsulfuration pathway ENSG00000116761 PMC8311004__F1 Necroptosis: A Novel Pathway in Neuroinflammation ENSG00000137275 ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC8531291__F6 Potential functional mechanism of SIRT3 in heat stress-induced BMECs ENSG00000116688 ENSG00000142082 ENSG00000171109 ENSG00000214253 PMC5908872__F5 B-cell receptor signaling pathway ENSG00000163624 ENSG00000169291 ENSG00000186716 PMC5998365__F1 Folate-mediated one-carbon metabolism ENSG00000228716 ENSG00000116984 PMC10985914__F2 Endogenous estrogen metabolites as oxidative stress mediators and endometrial cancer biomarkers ENSG00000140465 PMC1609340__F1 Outline of the TLR signalling pathway ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC8583797__F9 Tenofovir Modulates Semaphorin 4D Signaling and Regulates Bone Homeostasis, Which Can Be Counteracted by Dipyridamole and Adenosine A2A Receptor ENSG00000134215 ENSG00000169047 ENSG00000067900 ENSG00000187764 ENSG00000140443 PMC9168746__F1 Starch metabolism in potato photosynthesizing (leaves) and storage (tubers) organs ENSG00000159224 ENSG00000197386 PMC4877629__F3 Genetic networks generated from the differentially expressed genes from adipose tissues ENSG00000139193 ENSG00000140678 ENSG00000162458 ENSG00000187741 ENSG00000133789 ENSG00000185187 ENSG00000134061 ENSG00000111348 ENSG00000284925 ENSG00000213949 ENSG00000023892 ENSG00000088538 ENSG00000171560 ENSG00000115232 ENSG00000177425 PMC8234298__F1 Spotlight on Accessory Proteins: RTK-RAS-MAPK Modulators as New Therapeutic Targets ENSG00000136158 ENSG00000033327 ENSG00000140575 ENSG00000141068 ENSG00000099942 ENSG00000166068 ENSG00000108061 ENSG00000110395 ENSG00000169220 ENSG00000213658 ENSG00000164056 ENSG00000112851 ENSG00000022267 PMC9564207__F3 Targeting JWA for Cancer Therapy: Functions, Mechanisms and Drug Discovery ENSG00000167258 ENSG00000087245 ENSG00000140740 ENSG00000145321 ENSG00000185591 ENSG00000171791 PMC5593157__F5 The signaling pathway ENSG00000198793 PMC6316701__F2 Effect of SUMO on IFN pathways ENSG00000115415 ENSG00000184900 PMC7125809__F1 IFN signal transduction cascade and defects in this pathway ENSG00000159128 ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000033800 ENSG00000027697 ENSG00000142166 PMC4778363__F3 Pathway map for paramylon and wax ester metabolism in E.gracilis ENSG00000180210 ENSG00000166278 PMC6316701__F1 SUMO cycle ENSG00000161956 ENSG00000079387 ENSG00000163904 ENSG00000197579 ENSG00000142230 ENSG00000033800 ENSG00000153201 PMC9023181__F4 Molecular Correlates of Early Onset of Diabetic Cardiomyopathy: Possible Therapeutic Targets ENSG00000143799 ENSG00000112695 ENSG00000184983 ENSG00000117118 ENSG00000078668 ENSG00000143933 ENSG00000163295 ENSG00000178127 ENSG00000157184 ENSG00000181929 ENSG00000127184 ENSG00000131174 ENSG00000128609 ENSG00000213619 ENSG00000177606 ENSG00000284194 ENSG00000104325 PMC2756767__F2 Use of nuclear magnetic resonance-based metabolomics in detecting drug resistance in cancer ENSG00000159399 ENSG00000026103 PMC2756767__F3 Use of nuclear magnetic resonance-based metabolomics in detecting drug resistance in cancer ENSG00000198793 ENSG00000173599 ENSG00000159399 ENSG00000140443 PMC8264607__F9 Dihydrosphingosine driven enrichment of sphingolipids attenuates TGFB induced collagen synthesis in cardiac fibroblasts ENSG00000157933 ENSG00000170989 PMC3857727__F3 NMNATs, Evolutionarily Conserved Neuronal Maintenance Factors ENSG00000157064 PMC6281605__F2 Transcriptional landscape of mouse-aged ovaries reveals a unique set of non-coding RNAs associated with physiological and environmental ovarian dysfunctions ENSG00000171105 ENSG00000143549 ENSG00000147862 ENSG00000112559 ENSG00000171791 ENSG00000135480 ENSG00000136826 ENSG00000139618 ENSG00000114993 ENSG00000154133 ENSG00000274334 ENSG00000136997 ENSG00000146386 ENSG00000067955 PMC11076713__F8 Schematic model: The interferon and interleukin 27-dependent JAK-STAT signaling pathway ENSG00000167601 ENSG00000213928 ENSG00000187608 ENSG00000163568 ENSG00000163565 ENSG00000197272 ENSG00000142166 ENSG00000164430 ENSG00000108688 ENSG00000136869 ENSG00000104432 ENSG00000164342 ENSG00000124256 ENSG00000088827 ENSG00000185745 ENSG00000273686 ENSG00000105639 ENSG00000168610 ENSG00000172183 ENSG00000019582 ENSG00000108691 ENSG00000224320 ENSG00000105397 ENSG00000115415 ENSG00000108700 ENSG00000164136 ENSG00000026751 PMC3857727__F1 NMNATs, Evolutionarily Conserved Neuronal Maintenance Factors ENSG00000157064 ENSG00000173614 PMC6896083__F2 Schematic overview of CD147 associated partner, molecular pathway and microenvironment interaction involved in cancer progression ENSG00000291971 ENSG00000168610 ENSG00000148848 PMC7195839__F4 Non-linear reverse-engineering method for inferring genetic regulatory networks ENSG00000102145 ENSG00000159216 ENSG00000162676 ENSG00000148400 ENSG00000198728 ENSG00000135363 ENSG00000179348 PMC8154043__F1 Metabolic origins of non-photorespiratory CO2 release during photosynthesis: a metabolic flux analysis ENSG00000122966 ENSG00000172005 PMC5072731__F7 Uncovering the Complex Transcriptome Response of Mytilus chilensis against Saxitoxin: Implications of Harmful Algal Blooms on Mussel Populations ENSG00000172936 ENSG00000131323 ENSG00000168040 ENSG00000175104 ENSG00000143387 PMC5072731__F8 Uncovering the Complex Transcriptome Response of Mytilus chilensis against Saxitoxin: Implications of Harmful Algal Blooms on Mussel Populations ENSG00000149311 ENSG00000172936 ENSG00000164305 PMC4583193__F1 Targeting the HGF/c-MET Pathway in Hepatocellular Carcinoma ENSG00000019991 ENSG00000070831 ENSG00000163235 ENSG00000138798 ENSG00000198793 ENSG00000102119 PMC3001555__F1 Representation of the transduction pathway involved in Cd signaling ENSG00000173599 PMC11811070__F1 Pathways to apoptosis ENSG00000102871 ENSG00000171791 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC11811070__F2 Molecular mechanism of autophagy ENSG00000177169 ENSG00000152348 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC9353186__F7 Flavonoid Group of Smilax glabra Roxb. Regulates the Anti-Tumor Immune Response Through the STAT3/HIF-1 Signaling Pathway ENSG00000113520 ENSG00000118520 PMC3929669__F4 PPARG signaling pathway during high-altitude vs sea-level pregnancy ENSG00000175104 ENSG00000127191 ENSG00000132170 PMC4540190__F8 Schematic diagram outlining the novel molecular targets of CAFG leading to bone anabolic effects in osteogenic cells and fracture healing induced by BMP2/Wnt/Beta-catenin pathway ENSG00000170365 ENSG00000167941 ENSG00000168036 PMC6275309__F1 Molecular pathways of the neuro-immune hemostasis model ENSG00000134982 ENSG00000173599 ENSG00000196352 ENSG00000117335 PMC5430761__F9 Pathway showing role of Ror1in promoting tumor-cell growth, ENSG00000169071 ENSG00000065361 ENSG00000185483 ENSG00000168610 ENSG00000146648 PMC10671474__F2 Common mechanisms of secondary endocrine resistance in advanced ER+ breast cancer ENSG00000198793 ENSG00000087586 ENSG00000146648 ENSG00000196712 PMC11811070__F3 The main mitophagy pathways ENSG00000215021 ENSG00000123240 ENSG00000099968 ENSG00000158828 ENSG00000069509 PMC10671474__F1 Current endocrine and targeted treatment of metastatic ER+ breast cancer ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC11811070__F4 Pathways involved in necroptosis ENSG00000124256 ENSG00000137275 ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 ENSG00000026103 PMC3154935__F4 Influence of Stochastic Gene Expression on the Cell Survival Rheostat after Traumatic Brain Injury ENSG00000172680 ENSG00000002330 ENSG00000152495 ENSG00000198408 ENSG00000291971 ENSG00000138798 ENSG00000137845 ENSG00000168610 ENSG00000121966 ENSG00000089159 ENSG00000115415 ENSG00000137575 ENSG00000154188 PMC7195839__F3 Non-linear reverse-engineering method for inferring genetic regulatory networks ENSG00000129993 ENSG00000159216 ENSG00000148400 ENSG00000135363 ENSG00000179348 PMC6908489__F4 ROS contribute to ICAM-1 and PD-L1 induction in salivary gland epithelial cells through a JAK(1/)2/STAT3 pathway ENSG00000111537 ENSG00000168610 PMC8003559__F3 Activation of innate immune signaling pathway by lipopolysaccharide (LPS) and tumor necrosis factor (TNF) ENSG00000102871 ENSG00000172936 ENSG00000136869 ENSG00000154124 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC8294090__F11 Butorphanol Promotes Macrophage Phenotypic Transition to Inhibit Inflammatory Lung Injury via K Receptors ENSG00000172936 ENSG00000118520 ENSG00000276561 PMC4046121__F5A Differential Transcription of Fathead Minnow Immune-related Genes Following Infection with Frog virus 3, an Emerging Pathogen of Ectothermic Vertebrates ENSG00000137834 ENSG00000160973 ENSG00000037965 ENSG00000157933 ENSG00000133937 ENSG00000115297 ENSG00000156574 ENSG00000164093 ENSG00000175104 PMC10741879__F7 Schematic model showing the tumor-progression-promoting interaction between CRC cells and TAMs ENSG00000108691 ENSG00000198793 ENSG00000005893 ENSG00000108688 ENSG00000108700 PMC7071268__F3 Integrated overview of the metabolic changes induced by feeding the OBFR diet ENSG00000173599 ENSG00000105953 ENSG00000105552 ENSG00000062485 ENSG00000026103 PMC8146703__F6 Alteration in the Cerebrospinal Fluid Lipidome in Parkinson’s Disease: A Post-Mortem Pilot Study ENSG00000173599 ENSG00000099194 ENSG00000062485 ENSG00000026103 PMC5581678__F2 Entanglement of GSK-3B, Beta-catenin and TGFB1 signaling network to regulate myocardial fibrosis ENSG00000137834 ENSG00000134982 ENSG00000168036 PMC9182416__F2 Pharmacological, Neurochemical, and Behavioral Mechanisms Underlying the Anxiolytic- and Antidepressant-like Effects of Flavonoid Chrysin ENSG00000086991 PMC7958144__F1 Revisiting the Complexity of GLP-1 Action from Sites of Synthesis to Receptor Activation ENSG00000115263 ENSG00000157005 PMC5819894__F2 Apoptosis pathways ENSG00000132906 ENSG00000002330 ENSG00000168040 ENSG00000064012 ENSG00000164305 PMC12009697__F2 Activation of MAPK and PI3K/MTOR signaling pathways by oncogenic FGFR2 fusion protein ENSG00000196712 PMC10976388__S1 Depiction of Wnt Signaling Dysregulation in TNBC Cells When Compared to Healthy, Noncancerous Cells ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000155760 PMC3584002__F7 Model for GPN1, 2, and 3 function in biogenesis of RNA polymerases II and III ENSG00000111231 ENSG00000142751 PMC8088470__F3 Role and mechanisms of polycomb repressive complex 2 on the regulation of osteogenic and neurogenic differentiation of stem cells ENSG00000178860 ENSG00000029559 ENSG00000140968 ENSG00000109906 ENSG00000157601 ENSG00000291837 ENSG00000168036 ENSG00000022267 PMC5871976__F1 Moloney-murine leukemia virus (PIM) kinases regulate cancerous pathways ENSG00000002330 ENSG00000198793 ENSG00000136997 ENSG00000121966 PMC5871976__F2 Phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mTOR pathway adapted from figure 2 of and figure 1 of PMC5871976__F3 Interrelationship between PIM, AKT and mTOR adapted from figure 2 of PMC7360727__F2 Insulin signaling with highlighted in red pathways found to promote brain insulin resistance in AD and DS ENSG00000142192 ENSG00000169047 ENSG00000198793 PMC4267808__F4 The Shared Crosstalk of Multiple Pathways Involved in the Inflammation between Rheumatoid Arthritis and Coronary Artery Disease Based on a Digital Gene Expression Profile ENSG00000074800 PMC7360727__F3 Shared alterations between young DS and AD brain ENSG00000169047 ENSG00000198793 PMC5819894__F6 Metabolism pathways ENSG00000169710 ENSG00000078237 ENSG00000284194 PMC7090099__F3 Integrated analysis of GC-MS and LC-MS profiles ENSG00000112977 ENSG00000159224 PMC6095600__F3 Orthologous proteins of experimental de- and remyelination are differentially regulated in the CSF proteome of multiple sclerosis subtypes ENSG00000151726 ENSG00000172893 ENSG00000167508 ENSG00000168610 ENSG00000068079 ENSG00000019582 ENSG00000150782 ENSG00000167772 ENSG00000111537 ENSG00000170522 ENSG00000178573 ENSG00000139687 ENSG00000198911 PMC3829153__F8 Molecular mechanism of DSS-induced colitis in murine model ENSG00000167207 ENSG00000164690 ENSG00000133961 ENSG00000128602 PMC3461102__F1 Cell-Intrinsic Innate Immune Control of West Nile Virus Infection ENSG00000213928 ENSG00000105397 ENSG00000131323 ENSG00000164342 PMC3033173__F2 LMP1 in promoting survival in PTLD ENSG00000104856 ENSG00000102871 ENSG00000105639 ENSG00000184216 PMC5233609__F3 Canonical UPR pathway ENSG00000128272 ENSG00000127191 PMC7137946__F1 Biosynthesis and metabolic pathway of BH4 ENSG00000228716 ENSG00000171759 ENSG00000116096 PMC8468947__F1 Lactoferrin and Its Potential Impact for the Relief of Pain: A Preclinical Approach ENSG00000150782 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC6098163__F6 Crosstalk between RAAS and FGF-23 pathways ENSG00000118972 ENSG00000157933 ENSG00000130234 ENSG00000137672 ENSG00000077782 PMC5740609__F2 Cellular processes altered by colonization by a heterologous symbiont: (A) oxidative stress response; (B) molecular signaling pathways; (C) sugar storage, transport, and signaling; and (D) lipid and protein metabolism and transport ENSG00000143147 ENSG00000119688 ENSG00000151726 ENSG00000285482 ENSG00000173208 ENSG00000134780 ENSG00000112394 ENSG00000128602 ENSG00000075073 PMC6290060__F3 MAP of “p53 Signaling” pathway in (A) HSAEC and (B) A549 cells treated with 1 μM PG over 24 h ENSG00000152409 ENSG00000132646 ENSG00000177606 ENSG00000033800 ENSG00000137699 ENSG00000123374 ENSG00000112378 ENSG00000078237 ENSG00000284194 ENSG00000090530 ENSG00000026103 PMC1174965__F4 Regulation of lipopolysaccharide (LPS) signaling by suppressor of cytokine signaling 1 (SOCS1) ENSG00000111537 ENSG00000115415 ENSG00000172936 ENSG00000175104 PMC3814391__F7 DNA end resection ENSG00000175054 ENSG00000138346 ENSG00000132646 ENSG00000197299 ENSG00000051180 PMC5282886__F5 Critical factors involved in IGF-IR-mediated EMT process ENSG00000168036 PMC5282886__F6 IGF-IR signaling in CSCs-like cells biology ENSG00000198793 ENSG00000168610 PMC3276974__F2 Hypothetical model of LRRK2-mediated regulation of the miRNA pathway ENSG00000134042 PMC12055823__F4 TCM ameliorates DKD by modulating mTOR-mediated oxidative stress and nutrient sensing pathways ENSG00000177169 ENSG00000198793 ENSG00000096717 PMC5982769__F1 B cell receptor signaling pathway in mantle cell lymphoma ENSG00000070831 ENSG00000167323 ENSG00000095321 ENSG00000198793 ENSG00000010671 ENSG00000177455 ENSG00000095585 ENSG00000169291 ENSG00000110395 ENSG00000293604 ENSG00000146094 ENSG00000186716 ENSG00000177606 PMC7758250__F1 Immune responses elicited by Plasmodium infection ENSG00000162711 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000163568 ENSG00000125538 ENSG00000276561 PMC7349003__F2 Role of lncRNAs in the drug resistance of triple-negative breast cancer (TNBC) ENSG00000132383 ENSG00000165527 PMC5282886__F3 IGF signaling regulation in EMT ENSG00000169554 ENSG00000168036 ENSG00000164690 PMC12055823__F2 Oxidative stress and autophagy in diabetic nephropathy ENSG00000177169 ENSG00000150907 ENSG00000198793 ENSG00000158828 ENSG00000096717 ENSG00000168610 PMC7847333__F8 Schematic diagram ENSG00000281324 ENSG00000162337 ENSG00000167941 ENSG00000168036 PMC3712008__F3 Hypothetical representation of opposite downstream effects of two signaling pathways on the G1 phase of the cell cycle in a breast tumor-initiating cell ENSG00000095015 ENSG00000129355 ENSG00000065559 ENSG00000129757 ENSG00000135446 ENSG00000177606 ENSG00000107485 ENSG00000123374 ENSG00000105810 ENSG00000183779 ENSG00000077782 ENSG00000139687 ENSG00000140443 PMC6172484__F4 Gene network analysis of DE genes in the infected group ENSG00000120756 ENSG00000123191 ENSG00000140807 ENSG00000067842 ENSG00000112116 ENSG00000162949 ENSG00000186340 ENSG00000157578 ENSG00000145649 ENSG00000128342 ENSG00000078124 ENSG00000060566 ENSG00000108821 ENSG00000112115 ENSG00000073861 PMC12055823__F1 Nutrient sensing pathway and autophagy in diabetic nephropathy ENSG00000177169 ENSG00000128272 ENSG00000150907 ENSG00000112561 ENSG00000096717 ENSG00000057663 PMC8699445__F1 Biomarkers of Central Nervous System Involvement from Epithelial Ovarian Cancer ENSG00000149311 ENSG00000083093 ENSG00000051180 ENSG00000184207 ENSG00000139618 PMC5817805__F1 The BCR-ABL1 signaling pathways targeted by non ABL-directed inhibitors ENSG00000033327 ENSG00000186716 ENSG00000198793 ENSG00000171791 ENSG00000096717 ENSG00000128602 PMC3712008__F2 Subnetwork representation of protein interactions based on 78 mutated genes in 602 breast cancers - ENSG00000077522 ENSG00000198947 PMC8657692__F9 Evaluating the Effect of Lenvatinib on Sorafenib-Resistant Hepatocellular Carcinoma Cells ENSG00000160867 ENSG00000198793 ENSG00000146648 PMC6154333__F2 Possible apoptotic pathway induced by photoactivated ZnPcSmix in monolayer cells 24 h post PDT ENSG00000023445 ENSG00000132906 ENSG00000143514 ENSG00000138794 ENSG00000137875 ENSG00000151929 ENSG00000116717 ENSG00000064012 ENSG00000164305 PMC7758250__F2 Immune regulators in anti-malaria immunity ENSG00000163599 ENSG00000175592 ENSG00000276561 ENSG00000183735 ENSG00000089692 ENSG00000239732 ENSG00000088888 ENSG00000181847 ENSG00000172936 ENSG00000291555 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC11529444__F2 O-GlcNAcylation cycling and UDP-GlcNAc synthesis ENSG00000147162 ENSG00000198408 PMC3363007__F6 The Antioxidant Mechanisms Underlying the Aged Garlic Extract- and S-Allylcysteine-Induced Protection ENSG00000142192 ENSG00000125538 PMC2991480__F5 FC-66 expression of the Ingenuity NFKB Signaling canonical pathway ENSG00000226275 ENSG00000291603 ENSG00000244687 ENSG00000163235 ENSG00000138798 ENSG00000197943 ENSG00000150455 PMC10950925__F5 Ferroptosis Signaling Pathway ENSG00000167468 ENSG00000115107 ENSG00000115419 PMC11085255__F1 Molecular structure and signaling pathway activation mechanism of Nrf2 ENSG00000079999 ENSG00000124177 PMC11085255__F2 Regulation mechanism based on Nrf2 signal pathway ENSG00000171720 ENSG00000005882 ENSG00000010810 ENSG00000167468 ENSG00000096717 ENSG00000079999 PMC5966448__F6 Modeling the potential cellular roles of three genes upregulated by AnAc in MCF-7 and MDA-MB-231 cells ENSG00000131473 ENSG00000150907 ENSG00000166073 ENSG00000077463 PMC5662584__F4 Proposed mechanisms involved in in vitro anticancer activity of surfactin ENSG00000134057 ENSG00000123374 ENSG00000079557 PMC10950925__F2 Visualization of the extrinsic and intrinsic apoptosis pathway ENSG00000120868 ENSG00000168040 ENSG00000026103 PMC4385866__F2 Clinically relevant genes and regulatory pathways associated with NRASQ61 mutations in melanoma through an integrative genomics approach ENSG00000180210 ENSG00000196388 ENSG00000084092 ENSG00000111816 PMC1797585__F9 Working model for NS action ENSG00000002330 ENSG00000146648 PMC6154333__F3 Possible apoptotic pathway induced by photoactivated ZnPcSmix in MCTSs 24 h post PDT PMC138838__F1 Signaling through mammalian and Drosophila Toll-family receptors (TLRs) ENSG00000170458 ENSG00000172936 ENSG00000136869 PMC11085255__F3 Effects of natural products targeting Nrf2-related signaling pathway on myocardial ischemia ENSG00000162711 ENSG00000096717 ENSG00000283100 PMC5613237__F4 Galactose metabolism pathway ENSG00000134982 ENSG00000168036 ENSG00000123374 PMC6127641__F1 Possible cellular mechanisms attributed to oxidative stress in Parkinson’s disease (PD) and possible effects of natural antioxidants on specific pathway ENSG00000175054 ENSG00000158828 ENSG00000047936 PMC9561951__F2 Cellular autophagy, the compelling roles in hearing function and dysfunction ENSG00000112561 ENSG00000176165 ENSG00000198925 PMC5451151__F1 Anoikis signaling pathway in cancer cells ENSG00000291971 ENSG00000026103 PMC3710591__F7 Cellular protective response to MeHg through the Keap1-Nrf2 system ENSG00000178573 ENSG00000079999 PMC8003055__F6 Proposed mitochondrial pathway for apoptosis in HCC cells induced by compound 1 ENSG00000002330 ENSG00000135446 PMC7773022__F9 Proposed model of LPS/JNK/Sp1 or Nrf1 signaling pathways in regulation of TRIM59 expression ENSG00000213186 ENSG00000185591 ENSG00000106459 PMC4651715__F4 Three major signaling pathways that regulate cell size in normal cells.A ENSG00000157764 ENSG00000198793 ENSG00000155792 ENSG00000186654 PMC8934427__F2 Interplay Between Coronavirus and Type I IFN Response ENSG00000213928 ENSG00000088888 PMC9327801__F9 Isolation, Biosynthesis, and Biological Activity of Polycyclic Xanthones From Actinomycetes ENSG00000090402 ENSG00000166278 PMC10346248__F11 Schematic models of the NRF2 signaling pathway and its regulatory mechanisms in human skeletal muscle ENSG00000039537 ENSG00000079999 PMC6315839__F2 Model of biosynthesis and signal transduction of jasmonic acid (JA) and ethylene (ET) ENSG00000221818 ENSG00000104973 PMC6199329__F3 miRNA-regulated pathways in preovulatory granulosa cells ENSG00000137804 ENSG00000114346 ENSG00000178999 ENSG00000112118 ENSG00000112715 ENSG00000139618 ENSG00000137801 ENSG00000198901 ENSG00000094804 ENSG00000144554 ENSG00000171848 ENSG00000149554 ENSG00000095002 ENSG00000111247 PMC10145126__F2 PD-L1 regulation by IFNG ENSG00000115415 ENSG00000125347 PMC6199329__F4 Characterization of the miRNA regulators of the human ovulatory cascade ENSG00000145708 ENSG00000007237 ENSG00000119508 ENSG00000124766 ENSG00000112715 ENSG00000198056 ENSG00000173546 ENSG00000137801 ENSG00000138604 ENSG00000117122 ENSG00000129038 ENSG00000100592 ENSG00000157766 ENSG00000131149 ENSG00000138642 ENSG00000084072 ENSG00000114315 ENSG00000149554 ENSG00000095002 ENSG00000136040 PMC3573791__F1 The metalloproteases meprin A and meprin B: unique enzymes in inflammation, neurodegeneration, cancer and fibrosis ENSG00000140564 ENSG00000138798 PMC3696550__F6 Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia ENSG00000282905 ENSG00000134982 ENSG00000134215 ENSG00000163599 ENSG00000115904 ENSG00000110651 ENSG00000105647 ENSG00000135341 ENSG00000100485 ENSG00000121879 ENSG00000141968 ENSG00000177455 ENSG00000100290 ENSG00000077150 ENSG00000213658 ENSG00000149269 ENSG00000071051 ENSG00000164400 ENSG00000160293 ENSG00000198286 ENSG00000104365 ENSG00000100906 ENSG00000109320 ENSG00000198851 ENSG00000152689 ENSG00000213341 ENSG00000120910 ENSG00000221823 ENSG00000117020 ENSG00000111537 ENSG00000072694 ENSG00000135446 ENSG00000186716 ENSG00000177606 ENSG00000145321 ENSG00000285485 ENSG00000171608 ENSG00000131196 ENSG00000135605 PMC10527328__F1 Exploring the Molecular Landscape of Myelofibrosis, with a Focus on Ras and Mitogen-Activated Protein (MAP) Kinase Signaling ENSG00000157764 ENSG00000110395 ENSG00000117400 ENSG00000196712 PMC9476673__F3 Targeting immunometabolism by active ingredients derived from traditional Chinese medicines for treatment of rheumatoid arthritis ENSG00000160179 ENSG00000105953 ENSG00000103257 ENSG00000159399 ENSG00000062485 PMC2634987__F1 The GEP100-Arf6 pathway to invasion ENSG00000138798 ENSG00000165527 ENSG00000146648 PMC12248877__F1 PI3K/Akt/mTOR signaling pathway and the respective inhibitors used in TNBC ENSG00000198793 PMC3128624__F6 NRF2 Activation Restores Disease Related Metabolic Deficiencies in Olfactory Neurosphere-Derived Cells from Patients with Sporadic Parkinson's Disease ENSG00000185022 ENSG00000130522 ENSG00000173039 ENSG00000164031 ENSG00000197063 PMC7368075__F2 AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network ENSG00000167601 ENSG00000165801 ENSG00000066933 ENSG00000110031 ENSG00000284774 ENSG00000166477 ENSG00000124789 ENSG00000259956 ENSG00000102606 ENSG00000111859 ENSG00000160551 ENSG00000134982 ENSG00000089157 ENSG00000160710 ENSG00000112419 ENSG00000137807 ENSG00000112739 ENSG00000104320 ENSG00000168488 ENSG00000139726 ENSG00000084733 ENSG00000077782 ENSG00000196712 ENSG00000088387 ENSG00000168807 ENSG00000099901 ENSG00000166173 ENSG00000122257 ENSG00000204138 ENSG00000163431 ENSG00000106299 ENSG00000172403 ENSG00000177954 ENSG00000157106 ENSG00000061938 ENSG00000116641 ENSG00000144283 ENSG00000077420 ENSG00000164023 ENSG00000116584 ENSG00000146648 ENSG00000074054 ENSG00000164949 ENSG00000130726 ENSG00000172830 ENSG00000110237 ENSG00000105939 ENSG00000079482 ENSG00000178209 ENSG00000133121 ENSG00000121879 ENSG00000196396 ENSG00000089159 ENSG00000160007 ENSG00000113742 ENSG00000038382 ENSG00000065613 ENSG00000165458 ENSG00000151914 ENSG00000177600 ENSG00000024422 ENSG00000137145 ENSG00000125733 ENSG00000139926 ENSG00000025039 ENSG00000173517 ENSG00000144791 ENSG00000196411 ENSG00000186635 ENSG00000110880 ENSG00000087589 ENSG00000072786 ENSG00000163166 ENSG00000100941 ENSG00000126461 ENSG00000116191 ENSG00000137575 ENSG00000197555 ENSG00000139746 ENSG00000120896 ENSG00000149798 PMC3439136__F3 Additional analysis of the PPI network ENSG00000131469 ENSG00000265681 ENSG00000104237 ENSG00000223367 ENSG00000008988 ENSG00000197756 ENSG00000156482 ENSG00000198242 ENSG00000146648 ENSG00000144713 ENSG00000166508 PMC7375918__F4 Emerging Functions of Lactate in Regulating Signal Transduction and Gene Expression ENSG00000183735 ENSG00000134086 ENSG00000088888 ENSG00000101079 PMC3439136__F4 Dynamics in the RTK-Ras-ERK signaling network ENSG00000197756 ENSG00000198242 ENSG00000145592 PMC8484535__F1 Small RNAs: The Essential Regulators in Plant Thermotolerance ENSG00000228278 ENSG00000092847 ENSG00000134698 PMC6498879__F6 Comfrey’s mode of action by interference with the NFKB signaling pathway ENSG00000172936 ENSG00000175104 ENSG00000159335 ENSG00000184216 PMC3439136__F2 TAP-MS PPI RTK-Ras-ERK signaling network ENSG00000131469 ENSG00000265681 ENSG00000223367 ENSG00000197756 ENSG00000105401 ENSG00000156482 ENSG00000163902 ENSG00000198242 ENSG00000197728 ENSG00000010017 ENSG00000163918 ENSG00000177954 ENSG00000108107 ENSG00000175857 ENSG00000008988 ENSG00000171720 ENSG00000173992 ENSG00000174748 ENSG00000120438 ENSG00000146648 ENSG00000144713 PMC3875667__F2 Protect and serve: Bcl-2 proteins as guardians and rulers of cancer cell survival ENSG00000123374 ENSG00000095002 PMC7852227__F7 Schematic diagram ENSG00000088305 ENSG00000116761 PMC8863324__F1 Clinical Features and Serum Biomarkers in Identifying Patients with Incomplete Lupus Erythematosus at Higher Risk of Transitioning to Systemic Lupus Erythematosus: Current Perspectives ENSG00000134982 PMC7979537__F8 Repurposing dextromethorphan and metformin for treating nicotine-induced cancer by directly targeting CHRNA7 to inhibit JAK2/STAT3/SOX2 signaling ENSG00000168610 ENSG00000274542 PMC3011046__F2 FAS generates an endogenous ligand for PPARA in liver ENSG00000134255 ENSG00000026103 PMC4039369__F1 Yeast pathway map of nucleotide degradation and ribose salvage ENSG00000013375 PMC2921256__F1 Biology of the von Hippel-Lindau/hypoxia-inducible factor (VHL-HIF) axis in the setting of hypoxia or a mutation or aberration of the VHL gene product ENSG00000134086 ENSG00000163235 ENSG00000198793 ENSG00000146648 PMC4930294__F2 Signaling pathways important for stem/progenitor cells regulation ENSG00000063978 ENSG00000134982 ENSG00000183579 ENSG00000137845 ENSG00000172238 PMC5271588__F6 Cross-talk between apoptotic pathways ENSG00000168040 PMC4345829__F5 MicroRNAs (miRNAs) and autophagy (adapted with permission from Ventham et al, Gastroenterology) ENSG00000167207 ENSG00000136869 ENSG00000237693 PMC1683566__F5 Integration of gene expression with the proposed mechanistic pathway initiated by comfrey treatment leading to tumorigenesis ENSG00000174156 ENSG00000019991 ENSG00000105329 ENSG00000138798 ENSG00000169562 ENSG00000050748 ENSG00000167910 ENSG00000103222 ENSG00000196154 ENSG00000150967 ENSG00000162772 ENSG00000171791 ENSG00000121807 ENSG00000124762 ENSG00000186081 ENSG00000011422 ENSG00000128342 ENSG00000172867 ENSG00000087245 ENSG00000142192 ENSG00000116717 ENSG00000134871 ENSG00000186442 ENSG00000135480 ENSG00000007171 ENSG00000118785 ENSG00000148154 ENSG00000170477 PMC6571000__F6 T cell receptor signaling pathway and cytokine-cytokine receptor interaction affect the rehabilitation process after respiratory syncytial virus infection ENSG00000163464 ENSG00000291603 ENSG00000187796 ENSG00000134215 ENSG00000138798 ENSG00000241839 ENSG00000091409 ENSG00000183918 ENSG00000150782 ENSG00000140368 ENSG00000103490 ENSG00000125538 ENSG00000133740 ENSG00000277263 ENSG00000113263 ENSG00000283060 ENSG00000139626 ENSG00000159128 ENSG00000119535 ENSG00000115590 ENSG00000183691 ENSG00000132357 ENSG00000177663 ENSG00000197461 ENSG00000115607 ENSG00000120910 ENSG00000102245 ENSG00000010810 ENSG00000243646 PMC9599362__F3 NFKB Mutations in Germinal Center B-Cell Lymphomas: Relation to NFKB Function in Normal B Cells ENSG00000105369 ENSG00000239732 ENSG00000007312 ENSG00000186716 ENSG00000198793 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000198286 PMC11786704__F6 Schematic illustrates the signaling pathways involved in wound repair ENSG00000288269 ENSG00000115263 ENSG00000173599 ENSG00000177606 PMC9599362__F1 NFKB Mutations in Germinal Center B-Cell Lymphomas: Relation to NFKB Function in Normal B Cells ENSG00000104856 ENSG00000186716 ENSG00000173039 ENSG00000111321 PMC10454712__F2 Diagram of genes and metabolite pathways associated with the major secondary metabolites of tea plants ENSG00000115263 ENSG00000145321 ENSG00000198931 PMC7866651__F8 Diagram of regulated pathway in liver of GIFT exposed to acute hypoxia stress after 96 h ENSG00000171105 ENSG00000042832 ENSG00000170522 ENSG00000198125 PMC6078353__F4 KEGG pathway functional analysis of differentially expressed genes ENSG00000002330 PMC4890891__F3 Regulatory network of Katanin protein ENSG00000145826 ENSG00000113558 ENSG00000285246 ENSG00000127334 PMC7856673__F1 Current model of LOX-1-dependent signal transduction ENSG00000081041 ENSG00000076928 ENSG00000291971 ENSG00000162692 PMC5042386__F1 Schematic overview of the Hippo signaling pathway ENSG00000197905 ENSG00000114978 ENSG00000007866 ENSG00000131023 ENSG00000074219 PMC5042386__F2 Regulation of the Hippo signaling pathway in mammalian cells ENSG00000126016 ENSG00000186575 ENSG00000107186 ENSG00000134982 ENSG00000163914 ENSG00000197905 ENSG00000168036 ENSG00000007866 ENSG00000150457 ENSG00000132849 ENSG00000131023 ENSG00000074219 PMC5390871__F9 Lysophosphatidic acid‐induced itch is mediated by signalling of LPA5 receptor, phospholipase D and TRPA1/TRPV1 ENSG00000173599 ENSG00000198670 PMC6548759__F3 Results of Pancancer Pathway Panel analysis ENSG00000049323 ENSG00000111537 ENSG00000095739 ENSG00000100387 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000185591 ENSG00000164093 ENSG00000205250 ENSG00000137801 PMC3032410__F7 Dynamic Distribution of CARD11 at the Immunological Synapse is Regulated by the Inhibitory Kinesin GAKIN ENSG00000134982 ENSG00000175104 ENSG00000198286 PMC4212018__F1 Adaptive resistance to RAF inhibitors in melanoma ENSG00000157764 ENSG00000065361 ENSG00000146648 PMC9130585__F2 Pathophysiology of Primary Cilia: Signaling and Proteostasis Regulation ENSG00000140463 ENSG00000100360 ENSG00000100345 ENSG00000141577 ENSG00000164690 ENSG00000146648 ENSG00000078674 PMC7166181__F3 Signaling Pathways Regulated by PI3K/Akt/mTOR that Promote Neuritogenesis: A variety of ligands lead to neurite initiation and elongation through PI3K/Akt/mTOR signaling ENSG00000019991 ENSG00000070831 ENSG00000134982 ENSG00000198793 ENSG00000164327 ENSG00000067900 ENSG00000162772 PMC7382367__F3 Role of methyltransferase-like enzyme 3 and methyltransferase-like enzyme 14 in urological cancers ENSG00000138795 ENSG00000150093 ENSG00000168036 ENSG00000165819 PMC7407959__F1 Surgery and temporal sequence of icv ENSG00000164879 PMC4156265__F5 Pathway analysis ENSG00000096088 PMC3118704__F3 Toll-like receptor-4 (TLR-4) signaling via MyD-88-dependent pathways ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC6663492__F1 Pathways that may impact radiosensitivity ENSG00000198793 ENSG00000146648 PMC3367558__F1 Wnt signaling pathways ENSG00000134982 ENSG00000168036 PMC6528674__F3 Non-canonical Hippo signaling in the regulation of leukocyte function ENSG00000205744 ENSG00000049768 ENSG00000112115 ENSG00000168610 PMC3367558__F2 Wnt signaling at vertebrate neuromuscular junctions ENSG00000134982 ENSG00000149269 ENSG00000030304 ENSG00000163914 ENSG00000168036 ENSG00000277641 PMC10992393__F1 De novo synthesis of nervonic acid and optimization of metabolic regulation by Yarrowia lipolytica ENSG00000122966 ENSG00000140287 ENSG00000026103 PMC6528674__F4 Non-canonical Hippo signaling in the regulation of leukocyte function ENSG00000174125 ENSG00000172936 ENSG00000136869 PMC3367558__F3 Negative regulation of AChR clustering by Wnt3a ENSG00000154342 ENSG00000168036 PMC4001841__F1 PI3K-AKT pathway and associated cellular activities ENSG00000124102 ENSG00000002330 ENSG00000291971 ENSG00000168036 PMC3772101__F1 Transcriptional regulation by STAT1 and STAT2 in the interferon JAK-STAT pathway ENSG00000180182 ENSG00000213928 ENSG00000187608 ENSG00000115415 PMC9368934__F2 Stem Cell-Based Therapies for Inflammatory Bowel Disease ENSG00000178573 ENSG00000005381 ENSG00000079999 PMC9693551__F1 Modulatory Effect of Chlorogenic Acid and Coffee Extracts on Wnt/Beta-Catenin Pathway in Colorectal Cancer Cells ENSG00000134982 ENSG00000145321 ENSG00000026508 ENSG00000168036 ENSG00000146648 PMC6528674__F1 Non-canonical Hippo signaling in the regulation of leukocyte function ENSG00000150457 ENSG00000131023 PMC7927447__F2 Action of targeted therapies in PIRDs ENSG00000134982 PMC5079521__F1 Physiological mechanisms and therapeutic potential of bone mechanosensing ENSG00000008710 PMC5672004__F8 Pathways summary showing identified kinases in BTV infected cells ENSG00000002330 ENSG00000173846 PMC5313049__F9 Genome evolution in the allotetraploid frog Xenopus laevis ENSG00000130545 ENSG00000134982 ENSG00000178999 ENSG00000129355 ENSG00000114978 ENSG00000167074 ENSG00000168036 ENSG00000150457 ENSG00000071859 ENSG00000101224 ENSG00000118971 ENSG00000166851 ENSG00000117399 ENSG00000134480 ENSG00000186575 ENSG00000127184 ENSG00000184524 ENSG00000148204 ENSG00000116489 ENSG00000147082 PMC2387053__F2 Aging of the brain, neurotrophin signaling, and Alzheimer’s disease: is IGF1-R the common culprit? ENSG00000140443 PMC4055761__F3 Chromatin Remodelling Induced by the Freshwater Cyanotoxin Cylindrospermopsin in Human Intestinal Caco-2 Cells ENSG00000188786 ENSG00000137713 ENSG00000111057 ENSG00000280962 ENSG00000198265 ENSG00000133997 ENSG00000109911 ENSG00000124226 ENSG00000163681 ENSG00000091640 ENSG00000215301 ENSG00000130764 ENSG00000291745 ENSG00000163875 ENSG00000104343 ENSG00000120699 ENSG00000276043 ENSG00000221978 ENSG00000115946 ENSG00000058600 ENSG00000273772 ENSG00000100330 ENSG00000120616 ENSG00000135828 ENSG00000198625 PMC8527892__F2 Plasmin Cascade Mediates Thrombotic Events in SARS-CoV-2 Infection via Complement and Platelet-Activating Systems ENSG00000213928 ENSG00000125735 ENSG00000089127 ENSG00000183486 ENSG00000134215 ENSG00000157601 ENSG00000170454 ENSG00000163216 ENSG00000167916 ENSG00000184500 ENSG00000241794 ENSG00000095585 ENSG00000167656 ENSG00000288411 ENSG00000041982 ENSG00000156587 ENSG00000150907 ENSG00000163734 ENSG00000158825 ENSG00000164400 ENSG00000023445 ENSG00000104689 ENSG00000185479 ENSG00000197632 ENSG00000108342 ENSG00000185745 ENSG00000027697 ENSG00000167552 ENSG00000185885 ENSG00000276561 ENSG00000186529 ENSG00000154451 ENSG00000161921 ENSG00000134827 ENSG00000118503 ENSG00000139725 ENSG00000172602 ENSG00000059378 ENSG00000134070 ENSG00000131323 ENSG00000127824 ENSG00000111331 ENSG00000170477 ENSG00000115009 ENSG00000167553 ENSG00000100234 ENSG00000028277 ENSG00000123416 ENSG00000163739 ENSG00000188229 ENSG00000124107 ENSG00000150687 ENSG00000124875 ENSG00000179593 ENSG00000143556 ENSG00000104368 ENSG00000103811 ENSG00000144677 ENSG00000109819 ENSG00000132530 ENSG00000104140 ENSG00000130164 ENSG00000011422 ENSG00000163840 ENSG00000140379 ENSG00000163207 ENSG00000263528 ENSG00000128342 ENSG00000112299 ENSG00000136068 ENSG00000142627 ENSG00000081041 ENSG00000259207 ENSG00000100906 ENSG00000113070 ENSG00000113140 ENSG00000203785 ENSG00000130589 ENSG00000116701 ENSG00000073756 ENSG00000285348 ENSG00000166401 ENSG00000171631 ENSG00000115415 ENSG00000116106 ENSG00000137965 ENSG00000255398 ENSG00000142089 ENSG00000277276 ENSG00000156535 ENSG00000123689 PMC4590607__F3 Functional architecture of AXAN ENSG00000169228 ENSG00000104812 ENSG00000152348 ENSG00000104142 ENSG00000141564 ENSG00000136942 ENSG00000184056 ENSG00000215305 ENSG00000070669 ENSG00000078804 ENSG00000168010 ENSG00000127884 ENSG00000197769 ENSG00000053501 ENSG00000266173 ENSG00000163914 ENSG00000135932 ENSG00000132356 ENSG00000106617 ENSG00000166887 ENSG00000244038 ENSG00000108587 ENSG00000143669 ENSG00000130254 ENSG00000119125 ENSG00000134109 ENSG00000023287 ENSG00000198793 ENSG00000110931 ENSG00000258102 ENSG00000057663 ENSG00000107581 ENSG00000144848 ENSG00000136026 ENSG00000017260 ENSG00000166971 ENSG00000145782 ENSG00000116120 ENSG00000139719 ENSG00000177169 ENSG00000083290 ENSG00000167323 ENSG00000291973 ENSG00000111725 ENSG00000115592 ENSG00000142541 ENSG00000034713 ENSG00000162409 ENSG00000116649 ENSG00000139112 PMC6373340__F5 Insulin resistance mechanism and potential sites of vanadium activity ENSG00000180210 ENSG00000262785 ENSG00000135218 ENSG00000170522 ENSG00000173599 ENSG00000132478 ENSG00000198670 ENSG00000062485 ENSG00000026103 PMC7756379__F5 Proposed pathway for gladiostatin biosynthesis ENSG00000162924 ENSG00000145020 PMC5584733__F3 Rac1 in human diseases: The therapeutic potential of targeting Rac1 signaling regulatory mechanisms ENSG00000197429 PMC7174042__F1 Primary motor neuron components and lipidome pathways in MND/HSP ENSG00000110721 ENSG00000174915 ENSG00000167910 ENSG00000099377 ENSG00000241878 ENSG00000139163 ENSG00000100523 ENSG00000138135 ENSG00000032444 ENSG00000185813 ENSG00000173599 ENSG00000036530 ENSG00000156471 ENSG00000135929 PMC7174042__F2 PE and oxysterol pathways and the mitochondria-associated ER membrane (MAM) ENSG00000110721 ENSG00000174915 ENSG00000241878 ENSG00000032444 ENSG00000185813 ENSG00000155016 ENSG00000068615 ENSG00000116688 ENSG00000173599 ENSG00000147955 ENSG00000170855 ENSG00000156471 ENSG00000135929 PMC9104818__F5 Bone Progenitors Pull the Strings on the Early Metabolic Rewiring Occurring in Prostate Cancer Cells ENSG00000166340 ENSG00000075142 ENSG00000214078 ENSG00000165030 ENSG00000134215 ENSG00000157601 ENSG00000172409 ENSG00000159216 ENSG00000136295 ENSG00000198252 ENSG00000197136 ENSG00000187017 ENSG00000090924 ENSG00000198010 ENSG00000134440 ENSG00000291357 ENSG00000184985 ENSG00000260916 ENSG00000188559 ENSG00000168772 ENSG00000158859 ENSG00000124787 ENSG00000273645 ENSG00000120915 ENSG00000213341 ENSG00000285281 ENSG00000058673 ENSG00000133110 ENSG00000137992 ENSG00000145192 ENSG00000164855 ENSG00000198355 ENSG00000100150 ENSG00000135218 ENSG00000185215 ENSG00000106397 ENSG00000292211 ENSG00000244731 ENSG00000112715 ENSG00000158125 ENSG00000161955 ENSG00000161681 ENSG00000105664 ENSG00000185052 ENSG00000288499 ENSG00000197283 ENSG00000011028 ENSG00000120733 ENSG00000113790 ENSG00000123643 ENSG00000005339 ENSG00000169896 ENSG00000101265 ENSG00000168758 ENSG00000113140 ENSG00000149571 ENSG00000160691 ENSG00000128272 ENSG00000011304 ENSG00000278268 ENSG00000104133 ENSG00000112697 ENSG00000159399 ENSG00000132341 PMC8961331__F3 Interplay Between TGFB Signaling and Cell Metabolism ENSG00000198964 PMC9658815__F6 Recent Advances in Herbal-Derived Products with Skin Anti-Aging Properties and Cosmetic Applications ENSG00000181019 PMC8961331__F4 Interplay Between TGFB Signaling and Cell Metabolism ENSG00000118520 ENSG00000123505 PMC9658815__F5 Recent Advances in Herbal-Derived Products with Skin Anti-Aging Properties and Cosmetic Applications ENSG00000115138 ENSG00000107165 PMC9658815__F2 Recent Advances in Herbal-Derived Products with Skin Anti-Aging Properties and Cosmetic Applications PMC4360697__F2 Underlying link between Alzheimer’s disease and type 2 diabetes mellitus.Notes: Insulin resistance reduces the degradation of AB by IDE, and makes the combination of insulin and insulin receptor impaired ENSG00000142192 ENSG00000119912 PMC5507898__F8 Hypothetical model for the role of ASXL1 in cell cycle progression through the cooperation with AKT1 and EZH2 ENSG00000171456 ENSG00000123374 PMC9696306__F6 Screening for Hyperthermophilic Electrotrophs for the Microbial Electrosynthesis of Organic Compounds ENSG00000196549 ENSG00000116984 PMC5846498__F2 Novel bacterial ADP-ribosylating toxins: structure and function ENSG00000113070 ENSG00000138798 PMC7607069__F14 PPI network of TP53 signaling pathway genes (GeneMANIA) ENSG00000129028 ENSG00000168564 ENSG00000078900 ENSG00000122257 ENSG00000077721 ENSG00000105656 ENSG00000112659 ENSG00000067369 ENSG00000198625 PMC3521201__F1 Central carbon metabolism pathways in E ENSG00000261701 ENSG00000122966 ENSG00000197487 PMC4276873__F7 Tpl2-ERK activation during TLR signaling ENSG00000239732 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000164342 PMC7589016__F2 Intracellular signaling cascades activated by interaction of BDNF isoforms with its receptors ENSG00000175104 PMC11684189__F1 Cholesterol metabolic pathway ENSG00000138075 ENSG00000130164 ENSG00000042832 ENSG00000167910 ENSG00000015520 ENSG00000113161 ENSG00000073734 ENSG00000143921 PMC8609078__F6 CD200 Immune-Checkpoint Peptide Elicits an Anti-glioma Response Through the DAP10 Signaling Pathway ENSG00000091972 PMC3917357__F1 Functional properties of ion channels and transporters in tumour vascularization ENSG00000135605 PMC8173049__F7 Lactoferrin Retargets Human Adenoviruses to TLR4 to Induce an Abortive NLRP3-Associated Pyroptotic Response in Human Phagocytes ENSG00000278718 ENSG00000162711 ENSG00000137275 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000285379 PMC3640917__F4 Pathway for Death receptor signalling at 24 h post-M ENSG00000183735 ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC7982480__F1 Neuroprotective effects of ghrelin in PD ENSG00000154342 ENSG00000125538 ENSG00000168036 ENSG00000175567 ENSG00000125084 PMC4739739__F3 Connectivity of differentially expressed genes in the important signaling pathway following mixed PCBs exposure in human PBMC in vitro depicting the connectivity between genes expressed (with ≥1.5 fold change, t-test, p <0.05) ENSG00000167601 ENSG00000182901 ENSG00000104856 ENSG00000160789 ENSG00000254986 ENSG00000135439 ENSG00000050748 ENSG00000151835 ENSG00000171940 ENSG00000134308 ENSG00000145386 ENSG00000146457 ENSG00000057294 ENSG00000178685 ENSG00000276876 ENSG00000109854 ENSG00000005810 ENSG00000077150 ENSG00000291761 ENSG00000115419 ENSG00000253729 ENSG00000071575 ENSG00000142227 ENSG00000167987 ENSG00000095059 ENSG00000152332 ENSG00000044446 ENSG00000078369 ENSG00000162551 ENSG00000173039 ENSG00000167900 ENSG00000087460 ENSG00000139722 ENSG00000079999 ENSG00000174748 ENSG00000186716 ENSG00000155975 ENSG00000066136 ENSG00000074266 ENSG00000133422 ENSG00000178691 ENSG00000111786 PMC10855599__F2 JAK-STAT signaling pathway and PI3K-AKT signaling pathway that affect AD ENSG00000105397 ENSG00000169047 ENSG00000131724 ENSG00000168610 PMC2796182__F4 Regulation of nitric oxide signaling by thrombospondin-1: implications for anti-angiogenic therapies ENSG00000135218 ENSG00000291971 ENSG00000010810 ENSG00000198670 PMC6755424__F7 TGF-ß signaling pathway ENSG00000111537 ENSG00000095739 ENSG00000100387 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000137801 PMC2745153__F2 Multi-Target Approaches in Colon Cancer Chemoprevention Based on Systems Biology of Tumor Cell-Signaling ENSG00000138798 ENSG00000163914 ENSG00000168610 PMC5697091__F10 List of genes involved in the complement and coagulation cascades pathway generated by KEGG of the differently expressed genes between C ENSG00000039537 ENSG00000003436 ENSG00000113600 ENSG00000110799 ENSG00000088926 ENSG00000117322 ENSG00000185010 ENSG00000180210 ENSG00000126218 ENSG00000117525 ENSG00000175899 ENSG00000080618 ENSG00000062485 PMC6048758__F4 Regulation of SREBP1 and lipid metabolism by oncogenic signaling ENSG00000131473 ENSG00000138798 ENSG00000169710 ENSG00000146648 PMC8910032__F6 Senescent CD4+CD28− T Lymphocytes as a Potential Driver of Th17/Treg Imbalance and Alveolar Bone Resorption during Periodontitis ENSG00000291603 ENSG00000168610 PMC7672342__F3 Tuberous sclerosis: a review of the past, present, and future ENSG00000145979 ENSG00000155792 ENSG00000167965 PMC5473728__F1 Schematic Overview of the Norrin-Beta-Catenin PathwayMutations in the genes encoding the ligand Norrin, the receptors FZD4, LRP5, and TSPAN12, and now the transcriptional activator Beta-catenin all cause FEVR ENSG00000162337 ENSG00000106025 ENSG00000134982 ENSG00000174804 PMC5614322__F2 Hypothetic pathogenesis of OPLL ENSG00000178860 ENSG00000125398 PMC6134417__F1 抗表皮生长因子受体和抗血管内皮生长因子药物在非小细胞肺癌治疗中的作用 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC3296959__F2 Innate immunity and the ubiquitin–proteasome system in PD ENSG00000149311 ENSG00000187608 PMC8210559__F5 HOXA5 confers tamoxifen resistance via the PI3K/AKT signaling pathway in ER-positive breast cancer ENSG00000106004 ENSG00000170558 ENSG00000074266 ENSG00000178691 PMC2849832__F1 IFNG signaling through the JAK/STAT1 pathway ENSG00000159128 ENSG00000111537 ENSG00000115415 ENSG00000027697 ENSG00000168310 ENSG00000125347 ENSG00000230034 ENSG00000124762 PMC8910032__F3 Senescent CD4+CD28− T Lymphocytes as a Potential Driver of Th17/Treg Imbalance and Alveolar Bone Resorption during Periodontitis ENSG00000188486 ENSG00000149311 ENSG00000135446 ENSG00000105810 PMC7369353__F1 Main mechanisms of Wnt/Beta-catenin and PI3K/AKT/mTORC1 pathway interconnections ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000155792 ENSG00000168646 ENSG00000196628 PMC3750403__F3 BIOBASE-derived signaling network centered on p38 MAPK ENSG00000066926 ENSG00000136997 ENSG00000136869 ENSG00000134686 PMC9105968__F5 Lactoferrin as a Human Genome “Guardian”—An Overall Point of View ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 PMC6390476__F1 Schematic overview depicting regulatory pathways for PYY and GLP-1 secretion by enteroendocrine L-cell ENSG00000126266 ENSG00000131096 ENSG00000147262 PMC3480485__F5 Forkhead Box M1 (FoxM1) Gene Is a New STAT3 Transcriptional Factor Target and Is Essential for Proliferation, Survival and DNA Repair of K562 Cell Line ENSG00000149311 ENSG00000175054 ENSG00000113456 ENSG00000111537 ENSG00000197299 ENSG00000123268 PMC9319477__F6 Cyclic Hypoxia Induces Transcriptomic Changes in Mast Cells Leading to a Hyperresponsive Phenotype after FcERI Cross-Linking ENSG00000158869 PMC6351700__F2 Signaling model in a cell during tumor formation ENSG00000184232 ENSG00000198793 PMC6351700__F3 Schematic/proposed signaling model of role and regulation of claudins in a cell during invasive or metastatic stage ENSG00000281324 ENSG00000162337 ENSG00000291971 ENSG00000134982 ENSG00000198793 ENSG00000146648 PMC9236612__F8 Growth arrest and TRIM37 growth arrest activity ENSG00000108395 ENSG00000170037 ENSG00000107890 ENSG00000142731 PMC11088339__F5 Therapeutic application of adipose-derived stromal vascular fraction in myocardial infarction ENSG00000108691 ENSG00000198793 ENSG00000121807 ENSG00000175104 PMC7537941__F2 Activation of the coagulation cascade and endogenous anticoagulants ENSG00000003436 ENSG00000134982 ENSG00000122194 PMC11088339__F2 The transforming growth factor B (TGFB) signaling pathway in cardiac fibrosisTGFB regulate phenotypes of the cells through activation of mothers against decapentaplegic (SMAD)-related pathway together with p38 pathway PMC4000463__F1 JAK2 receptor signaling and activation of STAT pathway ENSG00000117400 ENSG00000168610 PMC5478092__F5 Metallothionein roles in aging and reactive oxygen species ENSG00000170653 PMC8398928__F1 Current Therapies in Clinical Trials of Parkinson’s Disease: A 2021 Update ENSG00000158828 PMC6879750__F5 Conserved and novel homologues of bilaterian genes involved in axis patterning and regulated by the Wnt/Beta-catenin signalling pathway in Hydra ENSG00000157554 ENSG00000138795 ENSG00000171956 ENSG00000159387 ENSG00000107807 ENSG00000064218 ENSG00000168036 ENSG00000136352 ENSG00000004848 ENSG00000119614 ENSG00000107485 ENSG00000171540 ENSG00000039600 PMC3636756__F1 Two kinases are required to promote mitotic entry ENSG00000276876 PMC11597433__F4 Wnt signaling pathway [04310] ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000095739 ENSG00000171444 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000108375 ENSG00000158941 ENSG00000185269 ENSG00000096717 PMC6944532__F3 Representative Examples of Gain-of-Function (GOF) Mutations That Perturb Signaling Pathways ENSG00000196557 ENSG00000169047 ENSG00000164362 PMC7198026__F2 Targeting STAT-3 signaling pathway in cancer for development of novel drugs: Advancements and challenges ENSG00000291971 ENSG00000137193 ENSG00000171791 ENSG00000168610 PMC5591914__F5 5-HT2A receptor antagonist contributing to DM-induced cardiovascular complications ENSG00000163914 ENSG00000162692 PMC3636756__F2 Two hypotheses for Gwl activation and mitotic entry ENSG00000128989 ENSG00000276876 PMC3636756__F3 CSF arrest is the result of a tight balance between PP2A-B55 and PP2A-B56 ENSG00000128989 ENSG00000134982 PMC5591914__F1 5-HT biosynthesis and metabolism in peripheral tissues ENSG00000139287 ENSG00000129167 ENSG00000173599 PMC2671376__F7 Signaling in the PI3K/Akt pathway and deregulations detected in GRMD skeletal muscle ENSG00000198793 ENSG00000119912 PMC10850268__F1 Signaling pathway of insulin action and the selective impairment of insulin receptor substrate (IRS)-protein kinase B (Akt) signaling pathway in insulin resistance ENSG00000140992 ENSG00000135218 ENSG00000150907 ENSG00000169047 ENSG00000198793 PMC7154126__F1 Interplay of glycolysis pathway with EMT factors ENSG00000019991 ENSG00000074800 ENSG00000160883 ENSG00000159399 PMC3046639__F1 RAS signaling pathway mutations and hypertrophic cardiomyopathy: getting into and out of the thick of it ENSG00000157764 ENSG00000110395 ENSG00000115904 ENSG00000166068 ENSG00000108061 ENSG00000196712 ENSG00000062485 PMC7830359__F1 Network of differentially expressed genes prior to initiation of anti-TNF therapy based on interactions using Ingenuity Pathway Analysis ENSG00000133106 ENSG00000135114 ENSG00000142089 ENSG00000169032 ENSG00000115523 ENSG00000159399 PMC6467501__F1 Xs and Y of immune responses to viral vaccines ENSG00000187608 ENSG00000291971 ENSG00000196839 ENSG00000163568 ENSG00000157601 ENSG00000109654 ENSG00000276561 ENSG00000172183 ENSG00000149311 ENSG00000137504 ENSG00000224320 ENSG00000116679 ENSG00000164136 ENSG00000026508 ENSG00000121060 ENSG00000143184 PMC7093136__F5 Summary of signaling pathways and molecular events induced by Chlamydia to promote inclusion development and EMT induction, leading to complications ENSG00000166863 ENSG00000146648 PMC8144171__F4 Functions and Targets of miR-335 in Cancer ENSG00000106571 ENSG00000198793 ENSG00000164690 ENSG00000150457 ENSG00000128602 ENSG00000131023 PMC2993607__F1 RB tumor suppressor: a gatekeeper to hormone independence in prostate cancer? ENSG00000168283 ENSG00000094804 ENSG00000135446 ENSG00000136997 ENSG00000168036 ENSG00000105810 PMC5372562__F2 Interaction and localization of proteins belonging to the integrin signaling pathway and found in samples 2 and/or 3 ENSG00000070087 ENSG00000070831 ENSG00000140983 ENSG00000241553 ENSG00000138071 ENSG00000165527 ENSG00000099942 ENSG00000197702 ENSG00000089159 ENSG00000111229 ENSG00000169750 ENSG00000143761 ENSG00000168374 ENSG00000124181 ENSG00000126458 ENSG00000155657 ENSG00000133818 ENSG00000115091 ENSG00000157764 ENSG00000143878 ENSG00000106299 ENSG00000181467 ENSG00000108518 ENSG00000149311 ENSG00000139725 ENSG00000006451 ENSG00000144118 ENSG00000171914 ENSG00000137076 ENSG00000130669 PMC5372562__F3 Interaction and localization of proteins, belonging to the angiopoietin signaling pathway and found in samples 2 and/or 3 ENSG00000104365 ENSG00000196455 ENSG00000109320 ENSG00000269335 ENSG00000105647 ENSG00000213341 ENSG00000179295 ENSG00000149311 ENSG00000077150 ENSG00000089685 ENSG00000126458 ENSG00000130669 ENSG00000133818 PMC7581770__F1A Systems analysis of avascular necrosis of femoral head using integrative data analysis and literature mining delineates pathways associated with disease ENSG00000182718 ENSG00000087245 ENSG00000128052 ENSG00000198931 ENSG00000100985 ENSG00000112715 ENSG00000117322 ENSG00000150630 PMC7472741__F2 SREBP-regulated mevalonate pathway and its regulation ENSG00000084093 ENSG00000110921 ENSG00000132196 ENSG00000130164 ENSG00000172893 ENSG00000149809 ENSG00000109929 ENSG00000197429 ENSG00000104549 PMC9586216__F1 Protein arginine methyltransferase 5 regulates SHH-subgroup medulloblastoma progression ENSG00000164690 ENSG00000128602 PMC7504523__F5 IFN signaling pathway suppressed by ADAR1 via the miR-302/367 cluster ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000276561 ENSG00000142166 PMC8958723__F3 In silico Prediction on the PI3K/AKT/mTOR Pathway of the Antiproliferative Effect of O. joconostle in Breast Cancer Models ENSG00000033327 ENSG00000002330 ENSG00000110395 ENSG00000169047 ENSG00000198793 ENSG00000164327 PMC2730524__F3 Translating insights from the cancer genome into clinical practice ENSG00000012048 ENSG00000136997 ENSG00000146648 PMC4939383__F1 NOD1 and NOD2: New Functions Linking Endoplasmic Reticulum Stress and Inflammation ENSG00000167207 ENSG00000100219 ENSG00000127191 ENSG00000106100 PMC2812679__F8 TK-mediated signaling pathway promoting HaCaT keratinocyte migration ENSG00000291971 ENSG00000113070 ENSG00000138798 PMC8897153__F1 Metabolic dysregulation and emerging therapeutical targets for hepatocellular carcinoma ENSG00000074800 ENSG00000092621 ENSG00000173599 ENSG00000189403 ENSG00000153574 ENSG00000159399 PMC5405564__F6 Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions ENSG00000053747 ENSG00000142798 ENSG00000134013 ENSG00000197102 ENSG00000178209 ENSG00000169710 PMC5449464__F4 Signaling and crosstalk associated with relaxin activation of its receptor RXFP1 ENSG00000145321 PMC7456455__F1 Monocytes represent a window between bone marrow and tissues ENSG00000182578 ENSG00000111537 ENSG00000119535 ENSG00000170458 PMC7422850__F4 Anti apoptotic effect of curcumin ENSG00000168040 PMC12255454__F6 The sphingolipid metabolic pathway and biochemical tools for its investigation ENSG00000167769 ENSG00000128699 ENSG00000221968 ENSG00000062282 ENSG00000143418 ENSG00000139624 ENSG00000223802 ENSG00000154227 ENSG00000100596 ENSG00000285482 ENSG00000172057 ENSG00000078124 ENSG00000119537 ENSG00000123353 PMC12255454__F7 Metabolic building blocks within the sphingolipid pathway and their subcellular localization ENSG00000139624 ENSG00000167769 ENSG00000100422 ENSG00000223802 ENSG00000154227 ENSG00000078124 ENSG00000113163 ENSG00000143418 PMC12255454__F8 Pathway map for individual molecular subspecies of sphingolipids beginning from production of the sphingoid base backbone through subsequent metabolic steps, emphasizing key branchpoints (nodes) ENSG00000112367 ENSG00000154227 ENSG00000147869 ENSG00000156574 ENSG00000143418 PMC4151463__F9 Function of integrin linked-kinase (ILK) in normal and activated stellate cells–implications for fibrogenesis in wound healing ENSG00000070831 ENSG00000163914 PMC5824489__F3 Sirtuins in Antioxidant and Redox Signaling ENSG00000172260 ENSG00000187531 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000283100 PMC11316721__F2 Molecular mechanisms of RBP4 in pancreatic Beta-cell function ENSG00000138207 ENSG00000115415 PMC8470622__F3 Epidermal Growth Factor Receptor Expression in the Corneal Epithelium ENSG00000163235 ENSG00000113070 ENSG00000138798 PMC7186717__F2 Influence of the Hippo-YAP signalling pathway on tumor associated macrophages (TAMs) and its implications on cancer immunosuppressive microenvironment PMC9131283__F8 5-HT2B-mediated serotonin activation in enterocytes suppresses colitis-associated cancer initiation and promotes cancer progression ENSG00000168610 PMC3735202__F3 Schematic diagram showing the Ras signalling pathway and its linkage to the GTPase cellular motility axis (Reproduced with permission from) ENSG00000002330 ENSG00000143878 ENSG00000138798 PMC8076293__F3 NFKB signalling cascade ENSG00000104856 ENSG00000164430 ENSG00000088888 ENSG00000173039 ENSG00000162924 ENSG00000131323 ENSG00000127191 PMC7003279__F5 Genes of differential proteins in the interaction network ENSG00000010704 ENSG00000169344 ENSG00000168743 ENSG00000072274 ENSG00000197746 ENSG00000203710 ENSG00000184207 ENSG00000124233 ENSG00000124157 ENSG00000104213 ENSG00000130164 ENSG00000196352 ENSG00000117335 ENSG00000198670 ENSG00000158874 ENSG00000089199 PMC7016816__F1 Schematic view of the ferroptosis pathway ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000072274 PMC10030510__F2 Metabolic regulation of dendritic cell activation and immune function during inflammation ENSG00000169710 ENSG00000159399 ENSG00000060762 PMC6617704__F7 Illustration of IPO5 involvement in CRC ENSG00000135446 ENSG00000105810 ENSG00000171791 PMC9023807__F3 MicroRNAs Are Key Molecules Involved in the Gene Regulation Network of Colorectal Cancer ENSG00000121879 PMC11316721__F1 Molecular mechanisms of RBP4 in insulin resistance ENSG00000169047 ENSG00000172936 ENSG00000136869 PMC9023807__F1 MicroRNAs Are Key Molecules Involved in the Gene Regulation Network of Colorectal Cancer ENSG00000170558 ENSG00000168036 PMC10030510__F4 Metabolic regulation of dendritic cell activation and immune function during inflammation ENSG00000183735 ENSG00000198793 ENSG00000159399 ENSG00000026103 PMC9023807__F2 MicroRNAs Are Key Molecules Involved in the Gene Regulation Network of Colorectal Cancer PMC5409774__F5 Comparative transcriptome and potential antiviral signaling pathways analysis of the gills in the red swamp crayfish, Procambarus clarkii infected with White Spot Syndrome Virus (WSSV) ENSG00000149311 ENSG00000002330 ENSG00000102871 ENSG00000164399 ENSG00000172936 ENSG00000120868 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC5409774__F6 Comparative transcriptome and potential antiviral signaling pathways analysis of the gills in the red swamp crayfish, Procambarus clarkii infected with White Spot Syndrome Virus (WSSV) ENSG00000168036 ENSG00000080166 ENSG00000107165 PMC5409774__F7 Comparative transcriptome and potential antiviral signaling pathways analysis of the gills in the red swamp crayfish, Procambarus clarkii infected with White Spot Syndrome Virus (WSSV) ENSG00000239732 ENSG00000144410 ENSG00000170458 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000164342 ENSG00000143387 PMC5031334__F6 Proposed biosynthetic pathway for ATM ENSG00000173599 ENSG00000117407 ENSG00000129744 ENSG00000291368 PMC2756538__F3 A model for the role of eEF-2K in the induction of autophagy during amino acid starvation and ER stress ENSG00000144895 ENSG00000284161 ENSG00000167658 PMC5661117__F8 Hippo pathway in mesothelioma cells ENSG00000186575 ENSG00000109321 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC3328790__F1 TGFB signaling pathway and its integration with other major pathways that is likely to be involved in the pathogenesis of cardiovascular diseases in elderly patients PMC5508596__F1 Wnt signaling pathways.(A) The canonical pathway is activated once Wnt binds to the frizzled (FZD) receptor and LRP-5/6 co-receptor, thus recruiting disheveled (DVL) protein that inhibits the Beta-catenin destruction complex ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000177606 ENSG00000168036 PMC4937870__F6 Activation of IL-8 and cyclin D1: proposed POP mixture pathway shared by inflammation and cancer ENSG00000106546 PMC4855182__F6 Ginsenoside Rg1 promotes osteogenic differentiation of rBMSCs and healing of rat tibial fractures through regulation of GR-dependent BMP-2/SMAD signaling ENSG00000178860 PMC7676939__F3 Androgen effects on the adrenergic system in the airway smooth muscle (ASM) ENSG00000174611 PMC4224073__F1 Complement system: an overview ENSG00000039537 ENSG00000113600 ENSG00000288512 ENSG00000244731 ENSG00000166278 ENSG00000122194 ENSG00000132693 ENSG00000182326 ENSG00000236625 PMC4069674__F1 Suppression of metastasis by mirtazapine via restoration of the Lin-7C/Beta-catenin pathway in human cancer cells ENSG00000147044 ENSG00000107282 ENSG00000168036 ENSG00000132535 ENSG00000148943 PMC3460211__F3 Formaldehyde-responsive miRNAs predicted to modulate MAM-associated genes in the brains of Mgmt−/− mice ENSG00000116106 ENSG00000265972 ENSG00000035928 ENSG00000145349 ENSG00000163281 PMC8815368__F3 BIRC5 was significantly enriched in the apoptosis pathway ENSG00000149311 ENSG00000291983 ENSG00000142192 ENSG00000002330 ENSG00000168040 ENSG00000164305 ENSG00000084774 PMC4935424__F4 Differentially expressed genes in BA, JA and UA groups mapped on the TNFR signaling pathway (1 denotes JA, 2 denotes UA, and 3 denotes BA) ENSG00000102871 ENSG00000168067 ENSG00000168040 ENSG00000115317 PMC2996105__F7 Interaction of p75NTR and TrkB signaling ENSG00000002330 PMC8156939__F2 PI3K/Akt Pathway: Emerging Roles in Skin Homeostasis and a Group of Non-Malignant Skin Disorders ENSG00000002330 ENSG00000169047 ENSG00000136997 ENSG00000038002 PMC2964746__F4 Selected signal transduction pathways that affect AS of transcripts of genes important in cancer ENSG00000096063 ENSG00000026103 PMC3209384__F8 Schematic showing the mechanism(s) of activation of the NLRP3 inflammasome and NFKB signaling pathways by vMyxM013-KO virus infection in human monocytic cell line THP-1 ENSG00000162711 ENSG00000125538 PMC6317881__F6 Interactions of genes involved in tumor progression and EMT ENSG00000101160 ENSG00000157766 ENSG00000170558 ENSG00000132646 ENSG00000196371 ENSG00000102575 ENSG00000120913 ENSG00000198598 ENSG00000171791 ENSG00000164305 PMC9111413__F2 Non‐steroidal anti‐inflammatory drugs and other eicosanoid pathway modifiers on antiviral and allergic responses: EAACI task force on eicosanoids consensus report in times of COVID‐19 ENSG00000137033 ENSG00000145777 ENSG00000166090 PMC10650444__F8 Compound 6b for promoting apoptosis of HepG2 cells ENSG00000109685 PMC4480161__F1 Cross-species comparison of PCD factors implicated in aging ENSG00000115317 ENSG00000214253 PMC9171412__F3 DNA damage initiates inflammatory signaling through DDR and cGAS‐STING. ATM‐NF‐kB pathway ENSG00000149311 ENSG00000162711 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC7599810__F1 Molecular pathogenesis of SARS-CoV-2 ENSG00000162711 ENSG00000130234 PMC6442448__F13 Mechanism by which GBE attenuates diabetic atherosclerosis ENSG00000128272 ENSG00000144895 ENSG00000198793 ENSG00000100219 ENSG00000127191 ENSG00000145782 PMC8393346__F2 Risks and Function of Breast Cancer Susceptibility Alleles ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000136492 ENSG00000083093 ENSG00000185379 ENSG00000104320 ENSG00000108384 ENSG00000149554 ENSG00000139618 ENSG00000183765 PMC8169786__F1 Recommendations for Vaccination in Children with Atopic Dermatitis Treated with Dupilumab: A Consensus Meeting, 2020 ENSG00000138378 ENSG00000186716 ENSG00000107485 PMC3255316__F1 Factors affecting the viability of dopamine neurons ENSG00000104327 ENSG00000130783 ENSG00000078070 ENSG00000149295 PMC3615879__F4 Action of 20-HETE.Notes: Mitogens and ligands of G-protein-coupled receptors activate PLA2 and induce release of arachidonic acid, which is converted by CYP4A/F to 20-HETE ENSG00000291971 ENSG00000146648 PMC9181425__F4 Thirty Years’ History since the Discovery of Pax6: From Central Nervous System Development to Neurodevelopmental Disorders ENSG00000111249 ENSG00000178403 ENSG00000084093 ENSG00000176399 ENSG00000136535 ENSG00000170558 ENSG00000061337 ENSG00000273529 ENSG00000114315 ENSG00000118971 ENSG00000291561 PMC3073350__F1 Linking actin dynamics and gene transcription to drive cellular motile functions ENSG00000163914 PMC9293526__F7 miR-26a-5p Suppresses Wnt/Beta-Catenin Signaling Pathway by Inhibiting DNMT3A-Mediated SFRP1 Methylation and Inhibits Cancer Stem Cell-Like Properties of NSCLC ENSG00000136997 ENSG00000168036 ENSG00000104332 PMC5852611__F1 Key players and stimuli in DRP1-mediated mitochondrial fission, both in physiologic and tumor conditions ENSG00000161956 ENSG00000203485 ENSG00000168958 ENSG00000104381 ENSG00000116030 ENSG00000175567 ENSG00000184900 PMC4346874__F1 Apoptosis pathways in cancer ENSG00000113600 ENSG00000002330 ENSG00000102871 ENSG00000082512 ENSG00000132478 ENSG00000120868 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC3863730__F6 Effects of Airway Microbiome on Corticosteroid Responsiveness in Asthma ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC10336275__F3 CREB-induced immune response ENSG00000173039 ENSG00000172936 ENSG00000175104 PMC6885218__F1 MTOR signaling pathway is involved in liver IR injury and plays crucial roles in autophagy ENSG00000149311 ENSG00000123395 ENSG00000126775 ENSG00000198793 ENSG00000148572 ENSG00000112561 ENSG00000164327 PMC4219296__F1 Wnt signaling pathway ENSG00000087095 ENSG00000281324 ENSG00000137673 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC2896868__F2 Toll-like receptors in kidney disease ENSG00000174125 ENSG00000173039 ENSG00000185187 ENSG00000150455 ENSG00000162772 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000170458 ENSG00000118503 ENSG00000187554 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC3982103__F1 Astrocytic–Neuronal–Astrocytic Pathway Selection for Formation and Degradation of Glutamate/GABA ENSG00000122966 ENSG00000173599 ENSG00000172005 PMC4742124__F1 Leptin signalling, obesity and prostate cancer: molecular and clinical perspective on the old dilemma ENSG00000168610 PMC11022384__F5 Therapeutic strategies targeting metabolism between GAMs and Gliomas ENSG00000172893 ENSG00000104549 ENSG00000160179 ENSG00000118520 PMC8634714__F2 Latest Developments in Immunomodulation of Mesenchymal Stem Cells in the Treatment of Intrauterine Adhesions, Both Allogeneic and Autologous ENSG00000137033 ENSG00000102871 ENSG00000145777 ENSG00000166090 ENSG00000127191 PMC11022384__F3 Metabolic characteristics of microglia ENSG00000198793 ENSG00000115419 PMC11022384__F4 Metabolic interactions between tumor cells and GAMs PMC8619244__F5 TRPV4 Mechanotransduction in Fibrosis ENSG00000163914 ENSG00000086991 PMC7865618__F3 Mechanism leading to CRS and ICANS and potential role of IL-1 blockade ENSG00000111537 ENSG00000110799 PMC7865618__F2 Different treatment strategies to modulate the IL-1–IL-1R pathway ENSG00000162711 ENSG00000137033 ENSG00000125538 ENSG00000136696 ENSG00000136694 PMC8619244__F2 TRPV4 Mechanotransduction in Fibrosis ENSG00000177606 ENSG00000135341 PMC8619244__F3 TRPV4 Mechanotransduction in Fibrosis ENSG00000092439 ENSG00000137672 ENSG00000138741 PMC8269357__F6 Identification of RNA-Binding Proteins Functionally Associated with Tumor Progression in Gastrointestinal Cancer ENSG00000099995 ENSG00000086589 ENSG00000136997 ENSG00000149273 ENSG00000087085 ENSG00000168610 ENSG00000119715 ENSG00000102974 PMC9962262__F3 Clocking Epilepsies: A Chronomodulated Strategy-Based Therapy for Rhythmic Seizures ENSG00000198793 ENSG00000069667 PMC11786704__S1 Preparation and application of PC capsules for promoting wound healing in diabetic mice ENSG00000173599 PMC7911265__F4 Portion of the human metabolic chart (online diagram: ), shown at its highest zoom level with all labels drawn, and displaying a reaction tooltip ENSG00000188641 ENSG00000196839 ENSG00000291814 ENSG00000124370 ENSG00000158825 ENSG00000119125 PMC6405412__F12 Role of AKR1C2 and AKR1C4 in male virilization ENSG00000151632 ENSG00000198610 ENSG00000203859 PMC6367847__F2 NLRP3 inflammasome pathways and putative mechanism by which cyclic stretch negatively regulates IL-1B secretion in murine macrophages ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC7487603__F1 Endothelial cell migration during sprouting angiogenesis ENSG00000161791 ENSG00000169071 ENSG00000070831 ENSG00000044115 ENSG00000150907 ENSG00000168036 ENSG00000112715 PMC7882619__F2 Irisin: A New Code Uncover the Relationship of Skeletal Muscle and Cardiovascular Health During Exercise ENSG00000198793 ENSG00000162692 PMC7697260__F3 Differences between the ECM− and ID+ fibroblast clusters are largely replicated in PDF and JDF spheroids, with distinct features present in PDF fibroblasts ENSG00000115008 ENSG00000100906 ENSG00000173039 ENSG00000108342 ENSG00000150093 ENSG00000165264 ENSG00000127540 ENSG00000196549 ENSG00000151366 ENSG00000291748 ENSG00000189043 ENSG00000110717 ENSG00000026508 ENSG00000169429 ENSG00000128342 ENSG00000119013 ENSG00000283060 ENSG00000258429 ENSG00000125968 ENSG00000172201 PMC5774508__F6 DEGs enriched KEGG map of the TNF signaling pathway in myocardial infarction ENSG00000078747 ENSG00000164136 ENSG00000007908 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC7697260__F4 Differences between the ECM− and ID+ fibroblast clusters are largely replicated in PDF and JDF spheroids with distinct features present in PDF fibroblasts ENSG00000106803 ENSG00000118363 ENSG00000058262 ENSG00000291748 ENSG00000258429 ENSG00000080573 ENSG00000125968 PMC2792482__F3 Integration of lipid metabolic and inflammatory signaling in macrophages by LXRs ENSG00000167207 ENSG00000136869 ENSG00000164342 PMC3437946__F8 Synthesis and degradation of dopamine, norepinephrine, and serotonin ENSG00000129167 ENSG00000123454 PMC6019726__F1 Production of IL-32 and its downstream signaling network ENSG00000167207 ENSG00000125538 ENSG00000106100 PMC5774508__F5 DEGs enriched KEGG map of the NFKB signaling pathway in myocardial infarction ENSG00000104856 ENSG00000143799 ENSG00000147862 ENSG00000242689 ENSG00000102871 ENSG00000138798 ENSG00000150455 ENSG00000095585 ENSG00000149311 ENSG00000226275 ENSG00000213658 ENSG00000170458 ENSG00000186716 ENSG00000162692 PMC2673908__F2 Unifying model of Wnt signaling with regard to cardiomyogenesis ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000125084 PMC6627629__F6 Proposed mechanisms for fucoidan-mediated inhibition of osteoclastogenesis ENSG00000131196 PMC3580884__F3 Relationship between binding of ligands to the pattern recognition advance glycation end‐product receptor (RAGE), and inflammation, gene expression, oxidative and nitrosative stress, and damage to the macro‐ and microvasculature ENSG00000198576 ENSG00000189403 PMC8476879__F3 Microglial Phenotypic Transition: Signaling Pathways and Influencing Modulators Involved in Regulation in Central Nervous System Diseases ENSG00000162711 ENSG00000172936 ENSG00000198670 PMC3278439__F4 Analysis of the Fibroblast Growth Factor System Reveals Alterations in a Mouse Model of Spinal Muscular Atrophy ENSG00000070831 PMC4442787__F3 Of BK regulation, painful connections, and versatile neuropeptide signaling ENSG00000115138 ENSG00000166603 PMC4572416__F3 Pathways to AT2 cell injury/dysfunction defined by using mutant proSP-C isoforms as prototype substrates ENSG00000102189 ENSG00000128272 ENSG00000135404 ENSG00000127191 PMC9020799__F11 RRx-001 Exerts Neuroprotection Against LPS-Induced Microglia Activation and Neuroinflammation Through Disturbing the TLR4 Pathway ENSG00000162711 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC8058998__F1 Phosphorylation events in TLR signaling ENSG00000183735 ENSG00000137275 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000010671 PMC4591933__F1 Non-invasive imaging and quantification of EGFR kinase activation in vivo ENSG00000138798 ENSG00000079432 ENSG00000146648 ENSG00000105205 PMC3579325__F3 Selected pathways from enriched injured (EI) versus non-enriched (i.e., STD housed) injured (NI): demonstrating calcium signaling importance ENSG00000186716 PMC9499793__F15 Therapeutic Effect of Gypenosides on Antioxidant Stress Injury in Orbital Fibroblasts of Graves' Orbitopathy ENSG00000198793 ENSG00000171791 PMC3808153__F7 The 5S RNP Regulates p53 Homeostasis and Its Activation in Response to Nucleolar and p14ARF OverexpressionSchematic overview showing the central role of the 5S RNP in coupling the pathway of ribosome biogenesis to cellular proliferation PMC8088111__F6 Signaling pathways involved in the effects of Mg2+ on CLS mediated by the GAAC pathway and Ecl1 family proteins ENSG00000180210 ENSG00000144895 PMC5647277__F1 Current view of the mechanisms responsible for activation and modulation of the reproductive axis in birds and mammals ENSG00000147437 ENSG00000158161 ENSG00000105516 ENSG00000134200 PMC5363674__F1 Scheme of the unfolded protein response (UPR) ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC3040753__F3 Gene Expression Profiling of Vasoregression in the Retina—Involvement of Microglial Cells ENSG00000196136 ENSG00000019582 ENSG00000231021 ENSG00000163131 ENSG00000244731 ENSG00000273686 ENSG00000167755 PMC10178209__F4 Biosynthetic pathway to produce patchoulol and Alpha- and Beta-santalol in S ENSG00000067064 ENSG00000197429 ENSG00000150787 PMC4818358__F1 Roles of interleukin-10 (IL-10) in determination of pregnancy ENSG00000205221 ENSG00000168610 PMC5480029__F1 Sulfide (S2−) homeostasis and small-molecule chemistry that couples reactive sulfur species (RSS) and reactive nitrogen species (RNS) ENSG00000182511 ENSG00000107798 PMC7197376__F1 Manipulating a tumour suppressor ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC8616335__F5 Cell Cycle Regulation and DNA Damage Response Networks in Diffuse- and Intestinal-Type Gastric Cancer ENSG00000149311 ENSG00000171444 PMC2718491__F3 Multiple regulatory pathways for N-WASP and WAVE2 activation ENSG00000070831 ENSG00000108798 ENSG00000105251 ENSG00000138443 ENSG00000213523 PMC9180634__F1 Molecular Mechanism of Induction of Bone Growth by the C-Type Natriuretic Peptide ENSG00000125398 ENSG00000115415 ENSG00000173786 ENSG00000096088 PMC3536698__F8 IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling ENSG00000169245 ENSG00000183735 ENSG00000088888 ENSG00000134321 ENSG00000185745 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC4162362__F1 The sphingolipid signaling pathway ENSG00000063176 ENSG00000183018 PMC7343375__F2 Abbreviated diagrammatic representation of the PI3K, Akt, mTOR cell signaling pathway, and associated pathways, as a major regulator of cell function (see Laplante and Sabatini for a more extensive chart of mTOR-related cell signaling) ENSG00000106070 ENSG00000145979 ENSG00000155792 ENSG00000112561 ENSG00000096088 PMC9406872__F1 Canonical Hedgehog Pathway and Noncanonical GLI Transcription Factor Activation in Cancer ENSG00000106571 ENSG00000164161 ENSG00000128602 PMC5098276__F4 CCI-779 treatment induces expression change in mTOR signaling pathway components ENSG00000157764 ENSG00000198793 ENSG00000164327 PMC8750192__F8 Osthole Inhibits Expression of Genes Associated with Toll-like Receptor 2 Signaling Pathway in an Organotypic 3D Skin Model of Human Epidermis with Atopic Dermatitis ENSG00000108691 ENSG00000172936 ENSG00000150455 ENSG00000175104 PMC9481585__F6 Discovery, isolation, heterologous expression and mode-of-action studies of the antibiotic polyketide tatiomicin from Amycolatopsis sp. DEM30355 ENSG00000166278 ENSG00000185010 PMC6478395__F3 BRAF mutations on tumor cell survival and the tumor microenvironment ENSG00000157764 ENSG00000198793 PMC3443855__F7 Nodal Signaling via an Autocrine Pathway Promotes Proliferation of Mouse Spermatogonial Stem/Progenitor Cells through Smad2/3 and Oct-4 Activation ENSG00000156574 PMC9406872__F2 Canonical Hedgehog Pathway and Noncanonical GLI Transcription Factor Activation in Cancer ENSG00000164161 ENSG00000198793 PMC8750192__F1 Osthole Inhibits Expression of Genes Associated with Toll-like Receptor 2 Signaling Pathway in an Organotypic 3D Skin Model of Human Epidermis with Atopic Dermatitis ENSG00000174125 ENSG00000150455 ENSG00000108691 ENSG00000239732 ENSG00000187554 ENSG00000172005 ENSG00000125538 ENSG00000169429 ENSG00000136869 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC9406872__F3 Canonical Hedgehog Pathway and Noncanonical GLI Transcription Factor Activation in Cancer ENSG00000164690 ENSG00000163501 PMC3588864__F7 Possible mechanisms of estrogen/androgen action in the prevention of NAFLD/NASH ENSG00000180210 ENSG00000113161 ENSG00000175567 PMC6504231__F8 Functional interplay of IL-21 with type I interferons in the response to MRSA ENSG00000103522 ENSG00000168610 PMC9321204__F4 Glycine betaine uptake and metabolism in marine microbial communities PMC9599896__F2 Cell-Cell Junctions in Oesophageal Squamous Cell Carcinoma ENSG00000170558 ENSG00000168036 ENSG00000099326 ENSG00000168646 ENSG00000146648 PMC11546914__F3 AI-Assisted Identification of Primary and Secondary Metabolomic Markers for Postoperative Delirium ENSG00000108691 ENSG00000169896 ENSG00000111537 ENSG00000128272 ENSG00000129226 ENSG00000090861 ENSG00000065427 PMC10507829__F4 Illustration of contributing factors of the signaling pathway for DDR1 in human adipose-derived MSC (A), (B), (C), which generated using ReactomeFIPlugIn in Cytoscape (B and C—enlarged parts of the image A) ENSG00000159216 ENSG00000020633 PMC10507829__F1 Extracellular matrix-induced signaling pathways in mesenchymal stem/stromal cells ENSG00000140992 ENSG00000002330 ENSG00000070831 ENSG00000291971 ENSG00000134215 ENSG00000138798 ENSG00000168036 ENSG00000150093 ENSG00000171791 ENSG00000169032 ENSG00000112715 ENSG00000213853 ENSG00000089159 ENSG00000160007 ENSG00000107263 ENSG00000129946 ENSG00000128052 ENSG00000130402 ENSG00000196914 ENSG00000118680 ENSG00000254445 ENSG00000168610 ENSG00000128710 ENSG00000117020 ENSG00000138193 ENSG00000010810 ENSG00000177606 ENSG00000015285 ENSG00000026508 ENSG00000137076 ENSG00000146648 ENSG00000130669 ENSG00000113360 PMC4431617__F1 Schema of the PI3K pathway ENSG00000198793 PMC2063513__F6 Gene Expression in Human Hippocampus from Cocaine Abusers Identifies Genes which Regulate Extracellular Matrix Remodeling ENSG00000196411 ENSG00000115221 ENSG00000100985 ENSG00000099822 PMC8348949__F2 Netrin-1 in Glioblastoma Neovascularization: The New Partner in Crime? ENSG00000065320 ENSG00000164690 ENSG00000128602 PMC6668446__F6 GLI1 activation by non-classical pathway integrin AvB3/ERK1/2 maintains stem cell-like phenotype of multicellular aggregates in gastric cancer peritoneal metastasis ENSG00000168283 ENSG00000128602 PMC5831511__F3 Brain-immune interactions in perinatal hypoxic-ischemic brain injury ENSG00000175104 ENSG00000184216 PMC5038987__F6 Proposed mechanism of the priming phase of complement-induced liver regeneration ENSG00000138135 ENSG00000113161 PMC5014907__F3 CD4+ T cell activation by antigen presenting cells and the IL-12/STAT4 pathway ENSG00000096996 ENSG00000138378 ENSG00000111537 ENSG00000105397 ENSG00000118503 ENSG00000134982 ENSG00000140968 ENSG00000163599 ENSG00000168685 PMC7674124__F1 Expression of PROK1 (A) and PROK2 (B) ENSG00000163421 ENSG00000164532 ENSG00000143125 PMC8592567__F2 Candidate signaling cascades that mediate the action of Indigo and polysaccharides via the gut ENSG00000110711 ENSG00000106546 PMC4925815__F1 Common mechanisms involved in Alzheimer's disease and type 2 diabetes: a key role of chronic bacterial infection and inflammation ENSG00000174125 ENSG00000150782 ENSG00000170458 ENSG00000140968 ENSG00000136869 PMC3615902__F3 Developmental data alters disease mechanism prediction ENSG00000178999 ENSG00000167513 ENSG00000170606 ENSG00000072571 ENSG00000137807 ENSG00000138778 ENSG00000148773 ENSG00000122691 ENSG00000089685 ENSG00000188257 ENSG00000001626 ENSG00000128342 ENSG00000078549 ENSG00000115163 ENSG00000175793 ENSG00000007908 ENSG00000100526 ENSG00000143228 ENSG00000126787 ENSG00000117399 ENSG00000117724 ENSG00000094804 ENSG00000065328 ENSG00000117650 ENSG00000156970 ENSG00000124882 ENSG00000172236 ENSG00000280610 PMC7752075__F2 Synthetic pathway of NO in ECs, inducers, inhibitors, the roles played and the effects of different components of the ECM ENSG00000135218 ENSG00000291971 PMC8012816__F7 Model depicting that PER3 regulates stemness of PCSCs via WNT/Beta-catenin pathway ENSG00000168036 PMC7824309__F3 Pathway enrichment analysis ENSG00000138798 ENSG00000133027 PMC7162481__F4 Genome-wide DNA methylation signatures to predict pathologic complete response from combined neoadjuvant chemotherapy with bevacizumab in breast cancer ENSG00000111057 ENSG00000157933 ENSG00000171049 ENSG00000196782 ENSG00000129514 ENSG00000171791 ENSG00000124762 ENSG00000171345 ENSG00000139354 ENSG00000116815 ENSG00000136240 ENSG00000158636 ENSG00000185591 ENSG00000275565 ENSG00000132819 ENSG00000169554 ENSG00000170214 ENSG00000138029 ENSG00000088305 ENSG00000198648 ENSG00000288335 ENSG00000145414 ENSG00000176884 ENSG00000111319 ENSG00000102245 ENSG00000164754 ENSG00000137575 ENSG00000258643 ENSG00000157450 ENSG00000131196 PMC3581534__F7 Bridging HIV-1 Cellular Latency and Clinical Long-Term Non-Progressor ENSG00000169248 ENSG00000095321 ENSG00000135838 ENSG00000186847 ENSG00000188042 ENSG00000069188 ENSG00000138134 ENSG00000064309 ENSG00000189058 ENSG00000100285 ENSG00000065361 ENSG00000109321 ENSG00000163666 ENSG00000091138 ENSG00000288461 ENSG00000120937 ENSG00000181704 ENSG00000109814 ENSG00000215021 ENSG00000214114 ENSG00000084764 ENSG00000184831 ENSG00000118482 ENSG00000120329 ENSG00000185339 ENSG00000127074 PMC8020202__F2 Roles and mechanisms of CBS/H2S and CSE/H2S system in breast cancer ENSG00000096717 ENSG00000168610 PMC3581534__F5 Bridging HIV-1 Cellular Latency and Clinical Long-Term Non-Progressor: An Interactomic View ENSG00000102230 ENSG00000166794 ENSG00000182481 ENSG00000108242 ENSG00000108231 ENSG00000107105 ENSG00000177954 ENSG00000265972 ENSG00000186818 ENSG00000128617 ENSG00000166508 ENSG00000108849 ENSG00000117525 ENSG00000182511 ENSG00000084072 ENSG00000152804 ENSG00000125656 ENSG00000047597 PMC8336719__F1 Roadmap for AHR targeting in skin inflammation ENSG00000172818 ENSG00000106546 PMC6901966__F10 Protective effects of farrerol on CDDP-induced AKI and the underlying mechanism ENSG00000162711 ENSG00000086991 ENSG00000079999 PMC4277277__F2 Snapshot of the Hepatic Transcriptome: Ad Libitum Alcohol Intake Suppresses Expression of Cholesterol Synthesis Genes in Alcohol-Preferring (P) Rats ENSG00000160752 ENSG00000110921 ENSG00000112972 ENSG00000172893 ENSG00000113161 ENSG00000104549 ENSG00000167508 ENSG00000148377 PMC6362265__F1 Three branches of the unfolded protein response (UPR) ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC9131376__F4 Recent Progress in the Development of Novel Mycobacterium Cell Wall Inhibitor to Combat Drug-Resistant Tuberculosis ENSG00000123999 ENSG00000026103 PMC5725016__F10 Chondroitin sulfatases differentially regulate Wnt signaling in prostate stem cells through effects on SHP2, phospho-ERK1/2, and Dickkopf Wnt signaling pathway inhibitor (DKK3) ENSG00000050165 PMC4481438__F1 Effect of ileal bile acid transporter in the proximal ileum ENSG00000180432 ENSG00000135929 PMC6868851__F3 Mechanism of miR21 in PC development ENSG00000002330 ENSG00000198793 PMC3663255__F1 Notch signaling pathway ENSG00000140564 ENSG00000168214 ENSG00000273529 ENSG00000133961 ENSG00000114315 PMC9529349__F1 Panax ginseng as a potential therapeutic for neurological disorders associated with COVID-19; Toward targeting inflammasome ENSG00000278718 ENSG00000162711 ENSG00000172936 PMC11661909__F4 Metastatic brain metastasis ENSG00000128512 ENSG00000168036 ENSG00000102854 ENSG00000168610 ENSG00000121966 ENSG00000141867 ENSG00000223802 ENSG00000149968 ENSG00000197594 ENSG00000177606 ENSG00000276051 ENSG00000134853 ENSG00000026508 ENSG00000146648 ENSG00000122512 PMC11685086__F1 FSH functions through the FSHR ENSG00000130164 ENSG00000113161 ENSG00000162692 PMC6354556__F1 Role of the biomarkers explored in the study on EGFR signaling ENSG00000167601 ENSG00000019991 ENSG00000291971 ENSG00000163814 ENSG00000168036 ENSG00000168610 ENSG00000146648 ENSG00000089159 ENSG00000237834 PMC9343460__F8 Effect of PINK1 on Alzheimer’s disease-like pathology induced by intracerebroventricular injection of forskolin in rats ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC11685086__F2 Action of FSH-FSHR in OC proliferation and EMT ENSG00000063176 ENSG00000170558 PMC11685086__F3 Nanotechnology and immunotherapy for ovarian cancer (OC) targeting FSHR ENSG00000159399 PMC4194125__F8 Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer ENSG00000073578 ENSG00000146411 ENSG00000111371 ENSG00000103257 ENSG00000091140 PMC6397348__F9 Diagram: BPI fold-containing group A member 1 (Bpifa1) regulation of noncanonical Toll-like receptor 4 (TLR4) and interferon (IFN) signaling ENSG00000169245 ENSG00000096996 ENSG00000213928 ENSG00000138378 ENSG00000111537 ENSG00000115415 ENSG00000198183 ENSG00000172936 ENSG00000136869 ENSG00000276561 PMC5192300__F2 The cellular trafficking of CD1 molecules ENSG00000158473 ENSG00000158481 ENSG00000158477 PMC4107957__F1 Toll-like receptors and TLR-mediated signaling pathway ENSG00000174125 ENSG00000150455 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000134070 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC5746140__F3 Implication from RAS/RAF/ERK signaling pathway increased activation in epirubicin treated triple negative breast cancer ENSG00000198793 ENSG00000127948 ENSG00000062485 PMC9291299__F4 Translation initiation and its relevance in colorectal cancer ENSG00000163435 ENSG00000128272 ENSG00000281324 ENSG00000120690 ENSG00000162337 ENSG00000144895 ENSG00000134982 ENSG00000174429 ENSG00000100664 ENSG00000146648 PMC8935981__F10 Comprehensive Analysis of Prognostic and Genetic Signatures for General Transcription Factor III (GTF3) in Clinical Colorectal Cancer Patients Using Bioinformatics Approaches ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000144554 ENSG00000132646 ENSG00000051180 ENSG00000095002 ENSG00000139618 PMC6034042__F4 Nicotinamide Adenine Dinucleotide (NAD+) synthesis pathways ENSG00000105835 ENSG00000278488 PMC6768428__F1 The STING signaling pathway ENSG00000124256 ENSG00000183735 ENSG00000164430 PMC2148066__F6 GenMAPP pathway showing changes in expression of the transcription factor PPARA and fatty-acid degrading enzymes upon fasting ENSG00000157184 ENSG00000117054 ENSG00000115425 ENSG00000138029 ENSG00000095321 ENSG00000115361 ENSG00000122971 ENSG00000113790 ENSG00000127884 PMC8759737__F1 SHP2-associated Noonan syndrome in RASopathy PMC10573607__F4 Soluble sugar, cellulose, and lignin contents ENSG00000177606 ENSG00000170549 ENSG00000084774 PMC7899014__F10 Cell signal transduction pathways of 7 central hub genes in CMs infected with SARS-CoV-2 ENSG00000171855 ENSG00000121807 ENSG00000122194 ENSG00000276561 ENSG00000108691 ENSG00000115415 ENSG00000130234 ENSG00000010810 ENSG00000177606 ENSG00000169429 ENSG00000136869 ENSG00000172936 ENSG00000175104 ENSG00000115594 PMC11215092__F1 Molecular pathways and targeted therapies in head and neck cancers pathogenesis ENSG00000281324 ENSG00000005339 ENSG00000162337 ENSG00000198793 ENSG00000168036 ENSG00000131023 ENSG00000168610 ENSG00000047644 ENSG00000177606 ENSG00000136997 ENSG00000168646 ENSG00000146648 ENSG00000109670 PMC3568707__F1 BiP as master regulator of the Unfolded Protein Response ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC1999497__F2 Flow diagram of the P53/apoptosis pathway ENSG00000120868 ENSG00000171791 PMC8663982__F4 Cytokine signaling inhibition on inflammation-driven tissue remodeling ENSG00000115415 ENSG00000168610 PMC8663982__F5 Cytokine signaling inhibition on inflammation-driven tissue remodeling ENSG00000137834 ENSG00000198793 PMC2680287__F1 Unraveling the complexities of the interferon response during SARS-CoV infection ENSG00000171855 ENSG00000213928 ENSG00000282905 ENSG00000187796 ENSG00000089127 ENSG00000183486 ENSG00000163565 ENSG00000157601 ENSG00000203710 ENSG00000142166 ENSG00000077150 ENSG00000103490 ENSG00000125538 ENSG00000233816 ENSG00000168310 ENSG00000164342 ENSG00000174125 ENSG00000066294 ENSG00000159128 ENSG00000100906 ENSG00000109320 ENSG00000115267 ENSG00000185745 ENSG00000027697 ENSG00000276561 ENSG00000172183 ENSG00000108691 ENSG00000111537 ENSG00000117091 ENSG00000105397 ENSG00000115415 ENSG00000137965 ENSG00000135114 ENSG00000112149 ENSG00000111331 PMC7293224__F7 Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation-mediated autophagy signaling pathway ENSG00000198793 ENSG00000144848 PMC10559873__F6 Detail of pathways ENSG00000148346 ENSG00000163220 ENSG00000133116 ENSG00000171759 ENSG00000007908 ENSG00000168040 ENSG00000111816 PMC5986469__F7 Illustration of the Compound-Group-Target-Pathway (CGTP) network ENSG00000180210 ENSG00000160752 ENSG00000277571 ENSG00000138207 ENSG00000291971 ENSG00000196549 ENSG00000123374 ENSG00000163631 PMC9180951__F5 Review on the Role of Bicarbonate and Proton Transporters during Sperm Capacitation in Mammals ENSG00000122986 ENSG00000091138 ENSG00000004939 PMC7573281__F4 Signaling pathways over-represented by genetic variants and differentially expressed genes Over-represented pathways and related genes are plotted ENSG00000092758 ENSG00000105486 ENSG00000160145 ENSG00000278316 ENSG00000132646 ENSG00000197943 ENSG00000182985 ENSG00000152767 ENSG00000177084 ENSG00000132639 ENSG00000137801 PMC5986469__F8 The interaction effects of enriched KEGG pathway terms and putative target proteins identified in the present study ENSG00000142192 ENSG00000113600 ENSG00000291971 ENSG00000129226 ENSG00000169032 ENSG00000122194 ENSG00000163631 ENSG00000180210 ENSG00000185386 ENSG00000149968 ENSG00000123374 ENSG00000077782 ENSG00000119912 ENSG00000146648 PMC7849831__F2 Mitochondrial dysfunction in astrocytes contributes to neuroinflammatory activation of astrocytes ENSG00000162711 ENSG00000164430 ENSG00000158828 PMC5273810__F4 IFN-gamma signaling pathway ENSG00000111537 ENSG00000111837 ENSG00000158169 PMC5273810__F6 Network analysis using key molecules in VL pathogenesis ENSG00000019991 ENSG00000291603 ENSG00000102871 ENSG00000169047 ENSG00000149782 ENSG00000168615 ENSG00000169032 ENSG00000102678 ENSG00000141867 ENSG00000173894 ENSG00000123496 ENSG00000112242 ENSG00000136997 ENSG00000123374 ENSG00000185591 ENSG00000128342 ENSG00000282899 ENSG00000140968 ENSG00000168040 ENSG00000125347 ENSG00000127191 ENSG00000168610 ENSG00000066468 ENSG00000111537 ENSG00000115415 ENSG00000177606 ENSG00000175104 ENSG00000178691 ENSG00000146648 PMC9709153__F6 Molecular mechanisms of exercise contributing to tissue regeneration ENSG00000100234 ENSG00000167941 ENSG00000198793 ENSG00000170653 ENSG00000171791 ENSG00000096717 ENSG00000163349 PMC11312265__F1 Molecular mechanisms of inhibited and activated canonical Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11312265__F2 Signaling cascade of non-canonical Wnt/PCP and Wnt/Ca2+ pathway ENSG00000087095 ENSG00000169071 ENSG00000070831 ENSG00000100592 ENSG00000163914 ENSG00000112655 ENSG00000185483 ENSG00000168036 PMC9709153__F4 Molecular mechanisms of exercise contributing to tissue regeneration ENSG00000101751 ENSG00000135446 PMC9709153__F2 Molecular mechanisms of exercise contributing to tissue regeneration ENSG00000281324 ENSG00000162337 ENSG00000167941 ENSG00000103335 ENSG00000108840 PMC11312265__F5 Non-canonical Wnt/PCP and Wnt Ca2+ signaling and their implications in cancer ENSG00000087095 ENSG00000173218 ENSG00000163914 ENSG00000026508 ENSG00000036828 PMC9709153__F3 Molecular mechanisms of exercise contributing to tissue regeneration ENSG00000179862 ENSG00000198793 ENSG00000140443 PMC9174462__F1 Pyroptosis and Its Role in Autoimmune Disease: A Potential Therapeutic Target ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000073605 PMC11802527__F2 Active ingredients of traditional Chinese medicine inhibit NOD-like receptor protein 3 inflammasome: a novel strategy for preventing and treating heart failure ENSG00000278718 ENSG00000162711 ENSG00000137275 ENSG00000161929 ENSG00000115594 PMC9602726__F5 GDF11 Regulates PC12 Neural Stem Cells via ALK5-Dependent PI3K-Akt Signaling Pathway ENSG00000133895 ENSG00000152661 ENSG00000142627 ENSG00000083168 ENSG00000153823 ENSG00000074319 ENSG00000115350 ENSG00000273686 ENSG00000121879 ENSG00000143156 ENSG00000111231 ENSG00000198176 ENSG00000004455 ENSG00000143393 ENSG00000163166 ENSG00000185591 ENSG00000155508 ENSG00000127824 ENSG00000164292 ENSG00000101290 PMC4855686__F2 CAMs can activate neurite outgrowth through different mechanisms ENSG00000070831 ENSG00000134982 ENSG00000143126 ENSG00000147133 ENSG00000008300 ENSG00000168036 ENSG00000169851 ENSG00000198910 PMC2848237__F2 Reconstruction of a KEGG pathway ENSG00000261832 ENSG00000094804 ENSG00000117399 PMC1952230__F1 Regulation of CXCR4 Signaling ENSG00000070831 ENSG00000291971 ENSG00000163914 PMC4972100__F1 The serine synthesis pathway and downstream anabolic reactions of serine ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC10982391__F1 Direct immunomodulatory function of TDEs on CD8+ T cells ENSG00000168283 ENSG00000147162 ENSG00000276051 ENSG00000118520 ENSG00000026103 PMC10982391__F2 TDEs indirectly regulate CD8+ T cells via the TME cells ENSG00000118520 ENSG00000100985 ENSG00000168961 PMC9598036__F4 Myelin repair in Alzheimer’s disease: a review of biological pathways and potential therapeutics ENSG00000182578 ENSG00000148400 ENSG00000010810 ENSG00000198793 ENSG00000169783 ENSG00000150093 ENSG00000118520 ENSG00000273529 PMC7583029__F1 Plant abiotic stress perception and response, concerning different cell compartments/organelles, and the terpenoid biosynthesis pathway ENSG00000172680 ENSG00000197429 ENSG00000167508 PMC9406972__F2 Tumour Derived Extracellular Vesicles: Challenging Target to Blunt Tumour Immune Evasion ENSG00000111537 ENSG00000134982 ENSG00000163599 ENSG00000243646 ENSG00000110324 ENSG00000026103 PMC4673119__F1 Regulation of T follicular helper cells by ICOS ENSG00000150907 ENSG00000188404 ENSG00000126353 ENSG00000170989 ENSG00000073861 ENSG00000110876 PMC6167501__F1 Exploring major signaling cascades in melanomagenesis: a rationale route for targetted skin cancer therapy ENSG00000177606 ENSG00000136997 ENSG00000131096 ENSG00000196712 PMC2939308__F1 Activation of PPARG and PTEN Cascade Participates in Lovastatin-mediated Accelerated Differentiation of Oligodendrocyte Progenitor Cells ENSG00000197971 ENSG00000135446 ENSG00000185591 ENSG00000100146 PMC4035704__F3 Transcriptional control of hepatic lipid metabolism by SREBP and ChREBP ENSG00000150907 PMC6167501__F7 TGFB signaling pathway in melanoma ENSG00000105329 PMC6167501__F8 Exploring major signaling cascades in melanomagenesis: a rationale route for targetted skin cancer therapy ENSG00000140564 ENSG00000128917 ENSG00000148400 ENSG00000074181 ENSG00000184916 ENSG00000090932 PMC6167501__F2 PI3K-Akt pathway activity ENSG00000140992 ENSG00000002330 ENSG00000150907 ENSG00000198793 PMC6167501__F4 Exploring major signaling cascades in melanomagenesis: a rationale route for targetted skin cancer therapy ENSG00000134982 ENSG00000168036 PMC5567140__F4 NCL expression affects cholesterol synthesis ENSG00000112972 ENSG00000172893 ENSG00000113161 ENSG00000099194 ENSG00000167508 ENSG00000052802 ENSG00000160752 ENSG00000067064 ENSG00000065833 ENSG00000132196 ENSG00000001630 ENSG00000170522 ENSG00000116133 ENSG00000152904 ENSG00000109929 ENSG00000149485 ENSG00000148377 PMC6167501__F5 Canonical and non-canonical NFKB signaling pathways ENSG00000104856 ENSG00000082512 ENSG00000162924 ENSG00000111321 ENSG00000127191 PMC9036418__F1 3q26 CNG activates PKCι-driven oncogenic signaling pathways in LUSC ENSG00000114346 ENSG00000149269 PMC11393980__F8 Other targets of pVHL in ccRCC and SNC hemangioblastomas ENSG00000163935 ENSG00000183735 ENSG00000178764 PMC5923293__F6 Ingenuity pathway analysis (IPA) of miR-152-3p-target interactions in prostate cancer signalling ENSG00000138795 ENSG00000139687 PMC10831402__F2 Suggested PML/RARA-related signaling pathway that leads to cell proliferation and the evasion of apoptosis ENSG00000168036 ENSG00000123374 ENSG00000140464 PMC7392626__F1 cGAS-STING pathway in oncogenesis and cancer therapeutics ENSG00000183735 ENSG00000164430 ENSG00000197594 ENSG00000131323 ENSG00000127191 PMC7392626__F2 cGAS-STING pathway in oncogenesis and cancer therapeutics ENSG00000169248 ENSG00000164430 ENSG00000101146 PMC9598036__F3 Myelin repair in Alzheimer’s disease: a review of biological pathways and potential therapeutics ENSG00000010810 ENSG00000198793 ENSG00000169783 ENSG00000133318 ENSG00000118520 ENSG00000273529 ENSG00000137845 PMC3253886__F4 IRF signaling pathway that was generated from pathway analysis of proteins with significant fold changes across both studies ENSG00000236637 ENSG00000088888 ENSG00000164342 PMC8663982__F2 Cytokine signaling inhibition on inflammation-driven tissue remodeling ENSG00000162711 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC10135928__F7 Lipid synthesis in adipocyte differentiation and functions ENSG00000178860 ENSG00000135218 ENSG00000042832 ENSG00000169710 ENSG00000285482 ENSG00000062282 PMC5338429__F7 Model of Gata4 transcriptional regulation in atrial septation ENSG00000285109 ENSG00000135446 PMC8663982__F3 Cytokine signaling inhibition on inflammation-driven tissue remodeling ENSG00000102871 ENSG00000198742 ENSG00000198793 ENSG00000136869 PMC7075706__F4 Intracellular pathways involved in proinflammatory effects of soluble uric acid ENSG00000162711 ENSG00000115008 ENSG00000125538 ENSG00000198793 ENSG00000105483 PMC3774987__F3 Essential TLR-associated signaling pathways and cytokine production ENSG00000174123 ENSG00000174125 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC6225629__F4 Reconstructed metabolic pathways (KEGG) of S ENSG00000197713 ENSG00000153574 ENSG00000198670 PMC5372268__F4 KEGG pathway hsa05200 “Pathways in cancer” ENSG00000099942 PMC4965259__F1 Presence of both alterations in FGFR/FGF and PI3K/AKT/mTOR confer improved outcomes for patients with metastatic breast cancer treated with PI3K/AKT/mTOR inhibitors ENSG00000198793 PMC7759681__F3 Function enrichment analysis of survival-related DEGs in STAD ENSG00000163935 ENSG00000157404 ENSG00000243364 ENSG00000186638 ENSG00000073111 ENSG00000075702 ENSG00000182957 ENSG00000172167 ENSG00000197586 ENSG00000183580 ENSG00000112964 ENSG00000092853 ENSG00000160182 ENSG00000160181 ENSG00000116741 ENSG00000005243 ENSG00000164736 ENSG00000198176 ENSG00000280610 ENSG00000110583 ENSG00000167646 ENSG00000188807 ENSG00000162444 ENSG00000149503 ENSG00000177570 ENSG00000138722 ENSG00000111300 ENSG00000128016 ENSG00000082397 ENSG00000135218 ENSG00000196187 ENSG00000113504 ENSG00000129596 ENSG00000161692 ENSG00000149548 ENSG00000155970 ENSG00000116830 ENSG00000120539 ENSG00000277236 ENSG00000177084 ENSG00000275718 ENSG00000122966 ENSG00000187961 ENSG00000106003 ENSG00000110042 ENSG00000276043 ENSG00000071564 ENSG00000123360 ENSG00000152669 ENSG00000013810 ENSG00000291631 ENSG00000178966 ENSG00000095002 ENSG00000123908 ENSG00000176619 PMC1993849__F7 Ischemic/hypoxic effects on cardiac myocytes and stem cells ENSG00000178860 ENSG00000168610 PMC3912696__F1 Role of cytokines in Th1 and Th2 differentiation of lymphocytes ENSG00000169245 ENSG00000102962 ENSG00000111537 ENSG00000138755 ENSG00000102970 ENSG00000106178 PMC10903931__F1 Hepatic phospholipid biosynthesis pathways ENSG00000042832 ENSG00000133027 PMC5134418__F2 Depiction of prasugrel metabolic pathway ENSG00000165841 ENSG00000197408 PMC6755131__F7 Extracellular annexin-A1 promotes myeloid/granulocytic differentiation of hematopoietic stem/progenitor cells via the Ca2+/MAPK signalling transduction pathway ENSG00000171049 ENSG00000197943 PMC10903931__F4 Apoptosis model induced by fatty acid metabolism ENSG00000042832 ENSG00000173599 PMC10903931__F5 LXR-LPCAT3-ERS signaling pathway ENSG00000128272 ENSG00000144895 ENSG00000111684 ENSG00000100219 ENSG00000127191 PMC8785421__F1 Signaling pathway and polymorphisms of Mrgprs ENSG00000104321 ENSG00000293604 ENSG00000138741 ENSG00000196689 PMC7047232__F6 Cartoon presentation of proposed cellular and molecular mechanisms for the synergistic effects of ATO/AA combination treatment ENSG00000132906 ENSG00000125538 ENSG00000171791 PMC6002396__F8 Model depicts the multiple mechanisms by which NXT inhibits the development of diabetic nephropathy in db/db mice ENSG00000087245 ENSG00000171105 ENSG00000105329 ENSG00000112715 PMC8615685__F3 Alterations of Plasma Galectin-3 and C3 Levels in Patients with Parkinson’s Disease ENSG00000162711 ENSG00000125538 ENSG00000136869 ENSG00000244731 PMC1853294__F10 Cell injury to wound closure, including P2Y activation, intracellular Ca2+ release and EGFR signaling ENSG00000291971 ENSG00000146648 PMC3321306__F1 Gene expression network of the heritable transcripts in the nuclear factor kappa B signaling pathway ENSG00000181163 ENSG00000102871 ENSG00000189403 ENSG00000106546 PMC10607207__F1 Neuroprotective intracellular signaling pathways in the central nervous system involving TRPC6 activation ENSG00000137672 ENSG00000109689 PMC8350724__F1 Pyroptosis, a New Breakthrough in Cancer Treatment ENSG00000278718 ENSG00000162711 ENSG00000150782 ENSG00000163568 ENSG00000125538 ENSG00000091592 ENSG00000091106 PMC3955095__F2 Targeting the Bcl-2 Family for Cancer Therapy ENSG00000002330 PMC8350724__F2 Pyroptosis, a New Breakthrough in Cancer Treatment ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC3937760__F4 miR-182 plays an important role in CEBPA/miR-122/IGF1R pathway ENSG00000245848 ENSG00000140443 PMC4355251__F2 PRR and signaling pathways that lead to differentiation of antifungal T-helper cells ENSG00000174125 ENSG00000162711 ENSG00000239732 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000162924 ENSG00000164342 PMC3887856__F1 Two branches of pathway upstream of mTORC1 ENSG00000168003 ENSG00000011566 ENSG00000130147 ENSG00000169047 ENSG00000155792 ENSG00000103257 PMC9085237__F16 Wild type and gain of function mutant TP53 can regulate the sensitivity of pancreatic cancer cells to chemotherapeutic drugs, EGFR/Ras/Raf/MEK, and PI3K/mTORC1/GSK-3 pathway inhibitors, nutraceuticals and alter metabolic properties ENSG00000078237 ENSG00000159399 PMC5436143__F6 Gain of function Beta-catenin in the uterine mesenchyme leads to impaired implantation and decidualization ENSG00000162552 ENSG00000082175 ENSG00000128342 ENSG00000163501 PMC3887856__F3 SH3BP4 is a potential tumor suppressor functioning in the amino acid-mTORC1 pathway ENSG00000130147 PMC4961512__F8 Curcumin and PKC signaling pathway in colon cancer ENSG00000146648 PMC6690952__F7 Schematic diagram depicting the mechanism by which suppressor of cytokine signaling 5 promotes or inhibits hepatocellular carcinoma cell metastasis via phosphoinositide-3 kinase/Akt/mammalian target of rapamycin pathway-mediated autophagy ENSG00000171150 ENSG00000198793 PMC10193376__F4 Protein network encoded by jointly regulated genes ENSG00000168438 ENSG00000130758 ENSG00000104142 ENSG00000132405 ENSG00000196268 ENSG00000171469 ENSG00000000971 ENSG00000196705 ENSG00000213096 ENSG00000213020 ENSG00000196586 ENSG00000149823 ENSG00000198740 ENSG00000156103 ENSG00000008516 ENSG00000164938 ENSG00000164068 ENSG00000152926 ENSG00000110987 ENSG00000146648 ENSG00000282899 PMC5346713__F8 Differentially expressed miRNAs in triple negative breast cancer between African-American and non-Hispanic white women ENSG00000206075 ENSG00000154342 ENSG00000138035 ENSG00000164109 ENSG00000136997 ENSG00000185129 ENSG00000113360 PMC5037849__F2 Dock3 signalling pathways in optic nerve regeneration ENSG00000134982 ENSG00000088538 PMC5746010__F1 Interactions of ALS/FTD associated genes with autophagy pathway ENSG00000177169 ENSG00000183735 ENSG00000123395 ENSG00000180667 ENSG00000123240 ENSG00000126775 ENSG00000167461 ENSG00000148572 ENSG00000165280 ENSG00000283741 ENSG00000147894 PMC446107__F1 TLR signaling pathways ENSG00000174125 ENSG00000239732 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000164342 PMC4116751__F1 Model Genetic Pathways ENSG00000138798 ENSG00000141068 ENSG00000146648 PMC5803300__F8 ANKRD11 associated with intellectual disability and autism regulates dendrite differentiation via the BDNF/TrkB signaling pathway ENSG00000167522 PMC7910861__F1 Evasion of RLR-mediated innate immunity through viral manipulation of ubiquitination and ISGylation ENSG00000135655 ENSG00000183735 ENSG00000088888 ENSG00000187608 ENSG00000083799 ENSG00000121060 ENSG00000276561 ENSG00000273820 PMC10420321__F8 Molecular mechanism underlying the beneficial effects of FJE in the OVA-induced CARAS mouse model ENSG00000137033 ENSG00000145777 PMC5790772__F1 Heparan sulfate proteoglycan (HSPG) protein family organization and HS biosynthesis ENSG00000182197 ENSG00000166278 PMC3775637__F3 Targeting the PI3K and BTK pathways in NHL ENSG00000136997 ENSG00000010671 PMC5363240__F5 Proposed role of RUNDC3B in the MAPK signalling pathway ENSG00000172680 ENSG00000105784 ENSG00000095321 ENSG00000136997 PMC3398478__F1 MAPK Pathways in S ENSG00000070831 ENSG00000167941 PMC5091087__F5 DEVELOPMENTAL CIGARETTE SMOKE EXPOSURE II: HIPPOCAMPUS PROTEOME AND METABOLOME PROFILES IN ADULT OFFSPRING ENSG00000125814 ENSG00000074800 ENSG00000146731 ENSG00000146701 ENSG00000127884 PMC4511315__F1 Schematic diagram for signaling regulation of acetylcholinesterase (AChE) ENSG00000138798 ENSG00000087085 PMC5319910__F4 Histone chaperone networks shaping chromatin function ENSG00000292096 ENSG00000100084 ENSG00000146872 ENSG00000073111 ENSG00000160949 ENSG00000198586 ENSG00000198700 PMC8687848__F8 Geniposide Attenuates Hyperglycemia-Induced Oxidative Stress and Inflammation by Activating the Nrf2 Signaling Pathway in Experimental Diabetic Retinopathy ENSG00000131095 PMC3821554__F1 The TGFB signaling pathway is regulated at multiple points by ubiquitin-mediated targeting and proteasomal degradation PMC7347075__F1 Metabolic kynurenine (Kyn) conversion pathway PMC4723075__F10 Differential Expression of the Activator Protein 1 Transcription Factor Regulates Interleukin-1ß Induction of Interleukin 6 in the Developing Enterocyte ENSG00000130522 ENSG00000175104 ENSG00000184216 ENSG00000115594 PMC3754784__F1 Toll-like receptor signaling in liver regeneration, fibrosis and carcinogenesis ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC4197719__F1 Mechanism of canonical HH signal transduction in vertebrates ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC9022290__F2 CD36, a signaling receptor and fatty acid transporter that regulates immune cell metabolism and fate ENSG00000157184 ENSG00000151726 ENSG00000135218 PMC8615614__F1 Targeting the PI3K/Akt/mTOR Pathway in Hepatocellular Carcinoma ENSG00000105723 PMC9669749__F2 Inflammatory pathophysiological mechanisms implicated in postpartum depression ENSG00000162711 ENSG00000049768 PMC3312677__F8 Genetic pathways involved in the regulation of the Mesp2 pathway ENSG00000283780 ENSG00000116106 ENSG00000203877 ENSG00000188095 ENSG00000149922 ENSG00000106003 PMC4364943__F10 Proposed model for the integration of NFAT and NFKB signalling pathwaysSwollen AF conidia are taken up by macrophages ENSG00000239732 ENSG00000172936 ENSG00000010671 PMC4937511__F10 Three pathways identified as altered based on the 12 SCI biomarker candidate proteins as input ENSG00000125166 ENSG00000169710 ENSG00000105656 ENSG00000163631 PMC3491811__F3 Calcium regulation of keratinocyte differentiation ENSG00000291971 ENSG00000010810 ENSG00000163914 ENSG00000168036 PMC4283519__F1 Signaling pathway interaction and effects of modulators: cGMP and cAMP-dependent intracellular signaling systems in the insulin-mediated regulation of platelet aggregation in patients with metabolic disorders ENSG00000115008 ENSG00000110799 ENSG00000145321 PMC4306233__F2 Roles of F-box proteins in cancer ENSG00000145604 ENSG00000177606 ENSG00000136997 ENSG00000155792 ENSG00000168036 ENSG00000112029 ENSG00000109670 PMC5082387__F2 TAM-dependent immunity ENSG00000184995 ENSG00000134982 PMC5173117__F3 Presence of TMPRSS2-ERG is associated with alterations of the metabolic profile in human prostate cancer ENSG00000116649 ENSG00000102172 PMC6830349__F2 Cell structure and function ENSG00000261832 ENSG00000130706 ENSG00000180667 ENSG00000173611 ENSG00000166278 PMC3494767__F5 Synergistic cancer cell death in response to stress when TSC2, but not Pten is inactivated in the context of a deregulated Rb pathway PMC8246597__F11 AMBRA1 regulates cyclin D protein stability and signalling through the RB pathway ENSG00000110497 ENSG00000158290 ENSG00000100387 ENSG00000135446 ENSG00000167986 ENSG00000105810 PMC7695248__F6 Sex-dependent metabolic and transcriptional changes after disrupted Cyp51 from cholesterol synthesis align with hepatocarcinogenesis in humans ENSG00000135218 ENSG00000042832 ENSG00000112964 ENSG00000168066 ENSG00000167910 ENSG00000111713 PMC5436606__F1 PD-1 and CTLA4: Two checkpoints, one pathway? ENSG00000134982 PMC6830349__F3 Diagram that illustrates the in situ flow of downregulated proteins (mark in green) in early development as a consequence of cAMP stimulation ENSG00000059691 ENSG00000103642 ENSG00000131473 ENSG00000136250 ENSG00000099194 ENSG00000105447 ENSG00000241878 ENSG00000107959 PMC8758946__F1 Making neurons, made easy: The use of Neurogenin-2 in neuronal differentiation ENSG00000136535 ENSG00000162761 ENSG00000163132 PMC8037903__F1 Role of gut in inducing adipose tissue inflammation ENSG00000170458 ENSG00000136869 PMC6927425__F4 Targeting Wnt signaling to combat cancer ENSG00000134982 ENSG00000168036 PMC11617596__F3 NAT10 plays a critical role in cancer ENSG00000167601 ENSG00000163516 ENSG00000172216 ENSG00000074181 ENSG00000105613 ENSG00000137203 ENSG00000135372 ENSG00000275272 PMC11617596__F4 Ac4C‐related signaling pathway in cancer ENSG00000170558 ENSG00000168036 ENSG00000135372 PMC6927425__F2 Non canonical Wnt signaling ENSG00000169071 ENSG00000070831 PMC7730553__F8 When LPS binds to TLR4 in the cell membrane, the resulting complex can lead to the activation of adaptor proteins including MyD88 and TIR-domain-containing adapter-inducing interferonB (TRIF) ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC12086256__F5 Interactions of vascular endothelial growth factor receptors (VEGFR) with co-receptors and structural features of Neuropilin ENSG00000116106 ENSG00000026508 ENSG00000077782 ENSG00000118257 ENSG00000146648 PMC12086256__F6 Signal transduction of vascular endothelial growth factor receptors ENSG00000107338 ENSG00000291971 ENSG00000010810 PMC12086256__F7 Negative regulation and fine-tuning of VEGFR2-mediated signaling pathways ENSG00000291971 ENSG00000112715 ENSG00000124181 PMC12086256__F8 VEGF/VEGFR signaling controls angiogenesis and vascular permeability ENSG00000291971 ENSG00000173599 PMC12086256__F9 VEGF/VEGFR signaling under pathological conditions ENSG00000291971 ENSG00000100985 ENSG00000112715 ENSG00000150630 PMC3472969__F1 Genotypic-phenotypic model of estrogen metabolism and exposure (yellow box represents genotype component with phenotypic factors outside) ENSG00000187837 ENSG00000140465 PMC11576426__F5 KEGG pathway “Regulation of actin cytoskeleton” (ssc04810) ENSG00000180210 ENSG00000134982 ENSG00000138443 ENSG00000181104 ENSG00000163914 ENSG00000198670 ENSG00000102302 ENSG00000121966 ENSG00000089159 PMC8920679__F3 Cellulosic Ethanol Production Using a Dual Functional Novel Yeast ENSG00000196344 ENSG00000100412 ENSG00000169299 ENSG00000013375 PMC3281071__F4 RNA-seq Reveals Novel Transcriptome of Genes and Their Isoforms in Human Pulmonary Microvascular Endothelial Cells Treated with Thrombin ENSG00000138798 ENSG00000163914 ENSG00000115904 ENSG00000146648 PMC9606402__F5 Gadd45b in neurologic and neuropsychiatric disorders: An overview ENSG00000198793 ENSG00000099860 PMC85642__F8 Schematic model of cyclin E-associated kinase activity as an integrative convergence point for the regulation of G1/S transition by the “classic” pRb/E2F and the “parallel” Myc-dependent pathways in mammalian cells (thick arrows) ENSG00000136997 ENSG00000123374 PMC11201617__F1 Molecular Mechanisms in Tumorigenesis of Hepatocellular Carcinoma and in Target Treatments—An Overview ENSG00000019991 ENSG00000138798 ENSG00000146648 PMC11201617__F2 Canonical activation of the WNT/Beta-catenin pathway ENSG00000204335 ENSG00000134982 ENSG00000168036 ENSG00000135111 PMC11201617__F3 Molecular Mechanisms in Tumorigenesis of Hepatocellular Carcinoma and in Target Treatments—An Overview ENSG00000087245 ENSG00000089685 ENSG00000019549 ENSG00000100985 PMC11201617__F4 Hippo signaling pathway ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC11201617__F6 Notch signaling pathway ENSG00000187957 ENSG00000125398 ENSG00000172889 ENSG00000171462 ENSG00000114315 PMC9533616__F5 lncRNA PVT1: a novel oncogene in multiple cancers ENSG00000213465 ENSG00000092847 ENSG00000104447 ENSG00000077782 ENSG00000168610 PMC9533616__F6 lncRNA PVT1: a novel oncogene in multiple cancers ENSG00000029363 ENSG00000137807 ENSG00000168283 ENSG00000169554 ENSG00000122691 ENSG00000150630 PMC9533616__F8 lncRNA PVT1: a novel oncogene in multiple cancers ENSG00000157554 ENSG00000011304 ENSG00000139644 ENSG00000102034 ENSG00000143839 ENSG00000165409 ENSG00000171791 ENSG00000081189 ENSG00000159399 ENSG00000140443 PMC2390552__F6 Analysis of Nodal signaling processes in ERK1MO and ERK2MO gene expression profiles ENSG00000170365 ENSG00000160973 ENSG00000164736 ENSG00000095739 ENSG00000109320 ENSG00000072401 ENSG00000138798 ENSG00000177606 ENSG00000156574 ENSG00000176165 ENSG00000114739 PMC2390552__F7 Analysis of FGF signaling processes in ERK1MO and ERK2MO gene expression profiles ENSG00000162889 ENSG00000164736 ENSG00000002330 ENSG00000167941 ENSG00000171241 ENSG00000156574 ENSG00000217236 PMC2390552__F8 Analysis of Wnt signaling processes in ERK1MO and ERK2MO gene expression profiles ENSG00000087095 ENSG00000164736 ENSG00000133937 ENSG00000169750 ENSG00000134982 ENSG00000131264 ENSG00000168036 ENSG00000179348 PMC2390552__F9 Analysis of BMP signaling processes in ERK1MO and ERK2MO gene expression profiles ENSG00000095739 ENSG00000175198 ENSG00000078369 ENSG00000183691 ENSG00000019549 ENSG00000134363 ENSG00000283060 ENSG00000204217 ENSG00000164619 ENSG00000114739 PMC7283470__F1 Emerging role of PTEN loss in evasion of the immune response to tumours ENSG00000163739 ENSG00000198793 PMC7028706__F9 Protein–protein interaction network generated for shared miRNA target genes after miRNET analysis ENSG00000111537 ENSG00000196839 ENSG00000198517 PMC5102796__F8 Model showing the relationship between HPV-induced replication stress, activation of the ATR/Chk1/E2F1 signaling pathway, RRM2 accumulation and productive viral replication ENSG00000175054 ENSG00000171848 PMC9533616__F3 lncRNA PVT1: a novel oncogene in multiple cancers ENSG00000177169 ENSG00000167772 ENSG00000144848 ENSG00000170430 ENSG00000187764 ENSG00000164690 ENSG00000159399 ENSG00000062716 ENSG00000149503 PMC9533616__F4 lncRNA PVT1: a novel oncogene in multiple cancers ENSG00000065978 ENSG00000169047 ENSG00000179431 ENSG00000112715 ENSG00000146648 PMC4985245__F1 IL-33 signaling pathway ENSG00000137033 ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000090376 PMC6895267__F9 The proposed working model ENSG00000143799 ENSG00000135372 ENSG00000133422 ENSG00000072609 PMC8150590__F1 Crosstalk between Interleukin-1B and Type I Interferons Signaling in Autoinflammatory Diseases ENSG00000162711 ENSG00000164430 ENSG00000125538 PMC7250673__F1 Bone Cell Communication Factors Provide a New Therapeutic Strategy for Osteoporosis ENSG00000164932 ENSG00000184347 ENSG00000187764 ENSG00000075213 PMC1774081__F6 Math1 signalling pathway ENSG00000159224 ENSG00000114315 PMC15871__F3 PI3′K signaling modules in mammals and nematodes have implications for cancer PMC3070611__F3 One experimental result of identified pathways from ovarian expression data ENSG00000221869 PMC6458848__F3 DEGs clustered in the PPAR signaling pathway PMC4337546__F7 Schematic diagram showing the cross talk between HCV and miR-373 inhibiting IFN signaling ENSG00000105397 ENSG00000115415 PMC3576710__F1 Transmembrane protein UNC93B1 (black spring-like shape) associates with various toll-like receptors (horseshoe-like shapes) in the endoplasmic reticulum to help load them into vesicles coated with COPII for transport to the Golgi ENSG00000239732 ENSG00000164342 PMC7537965__F1 Workflow for drug and vaccine repurposing ENSG00000277336 ENSG00000115008 ENSG00000110330 ENSG00000198890 ENSG00000100429 ENSG00000187840 ENSG00000235098 ENSG00000101161 ENSG00000173221 ENSG00000117525 ENSG00000182853 ENSG00000111537 ENSG00000121068 ENSG00000168066 ENSG00000168461 ENSG00000171435 ENSG00000085265 ENSG00000113520 ENSG00000164400 ENSG00000159335 ENSG00000162892 ENSG00000115009 ENSG00000025293 ENSG00000106178 PMC7307829__F5 Analysis of TLK1 interactome and hypothetical pathway ENSG00000150991 ENSG00000070831 ENSG00000134057 ENSG00000010810 ENSG00000087586 ENSG00000123374 ENSG00000166851 ENSG00000089159 ENSG00000198586 PMC3070611__F4 One of experimental result from pathways intersection ENSG00000124102 ENSG00000163914 ENSG00000121988 ENSG00000221869 ENSG00000273529 ENSG00000114315 PMC3070611__F5 The shortest pathway identified by our system ENSG00000153879 ENSG00000221869 PMC7537965__F4 A venn diagram showing overlaps between BCG genetic mimics and key hubs with SARS-CoV-2 and Corona viruses interactomes ENSG00000197081 ENSG00000122966 ENSG00000137275 ENSG00000078369 ENSG00000164251 ENSG00000169136 ENSG00000166090 ENSG00000137563 ENSG00000104368 ENSG00000281766 ENSG00000070756 ENSG00000141867 ENSG00000111537 ENSG00000073060 ENSG00000143801 ENSG00000128609 ENSG00000213619 ENSG00000164615 ENSG00000147955 ENSG00000124523 ENSG00000138398 PMC5902028__F2 TIGIT pathway ENSG00000153283 ENSG00000181847 ENSG00000134982 ENSG00000010810 ENSG00000150637 PMC3244904__F4 Eukaryotic Phospholipid Synthesis and Editing.G3P produced by GPDH is converted to PA by sequential acylation reactions regulated by GPAT and LPAAT ENSG00000173599 ENSG00000184207 PMC10874582__F2 Immune-related signalling pathways in mosquitos ENSG00000100697 ENSG00000172936 ENSG00000113360 ENSG00000123908 PMC12234771__F4 Comprehensive strain‐identification pathway for the seven UCYN‐A strains, established by the codon aversion motifs of the 40 genes ENSG00000197713 ENSG00000198576 ENSG00000153574 PMC8583315__F1 WNT/Beta-Catenin Pathway in Soft Tissue Sarcomas: New Therapeutic Opportunities? ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000102312 ENSG00000183579 ENSG00000185483 ENSG00000168036 ENSG00000108375 PMC8165552__F1 Mitochondrial NADH pool is involved in hydrogen sulfide signaling and stimulation of aerobic glycolysis ENSG00000125166 ENSG00000137767 ENSG00000166278 ENSG00000146701 PMC8583315__F3 WNT/Beta-Catenin Pathway in Soft Tissue Sarcomas: New Therapeutic Opportunities? ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000050165 ENSG00000102312 ENSG00000183579 ENSG00000185483 ENSG00000168036 ENSG00000108375 PMC6411635__F2 Metabolic reprogramming of T cells after allogeneic stem cell transplantation ENSG00000160883 ENSG00000198793 ENSG00000159399 ENSG00000026103 PMC7492732__F1 Biosynthesis of kinamycin ENSG00000110711 ENSG00000162551 ENSG00000163295 PMC2932677__F1 Diversity and Plasticity of Th Cell Types Predicted from Regulatory Network Modelling ENSG00000100385 ENSG00000134460 ENSG00000134982 PMC5983613__F5 Leptin is a very important factor that links fatty acid Beta-oxidation with oocytes maturation ENSG00000157184 ENSG00000117054 ENSG00000138029 ENSG00000133835 ENSG00000137193 ENSG00000143324 ENSG00000122971 ENSG00000127884 PMC10998350__F5 Pyrroloquinoline quinone promotes human mesenchymal stem cell-derived mitochondria to improve premature ovarian insufficiency in mice through the SIRT1/ATM/p53 pathway ENSG00000149311 ENSG00000132604 ENSG00000096717 PMC9239034__F1 Expression Profile of Genes Related to the Th17 Pathway in Macrophages Infected by Leishmania major and Leishmania amazonensis: The Use of Gene Regulatory Networks in Modeling This Pathway ENSG00000099985 ENSG00000115415 ENSG00000177606 ENSG00000155313 ENSG00000127191 ENSG00000115009 PMC5921304__F6 Metabolic enzymes belonging to the most divergent group (protein sequence identity) in the context of carbohydrate metabolism ENSG00000118094 PMC6436646__F2 Calcium signaling pathways and their effects on the calcium responsive percentage of chondrocytes ENSG00000141086 PMC8301219__F3 Immune Checkpoint Inhibitors in Human Glioma Microenvironment ENSG00000069482 PMC2787458__F9 Wnt3a stimulates Src docking to, activation by, and phosphorylation of Dvl2 ENSG00000004975 ENSG00000154342 ENSG00000281324 ENSG00000162337 ENSG00000291971 ENSG00000168036 PMC9168090__F9 Analysis of the Underlying Mechanism of the Jiu Wei Zhen Xin Formula for Treating Generalized Anxiety Disorder Based on Network Pharmacology of Traditional Chinese Medicine ENSG00000124102 ENSG00000182533 ENSG00000130528 ENSG00000156026 PMC3694614__F9 Free Radical-Producing Myeloid-Derived Regulatory Cells: Potent Activators and Suppressors of Lung Inflammation and Airway Hyperresponsiveness ENSG00000102962 PMC7655095__F7 The Gb3‐cSrc correlated mutant p53 signaling pathways ENSG00000168036 ENSG00000165819 ENSG00000164949 PMC6955783__F5 RNAseq genes associated with NRF2-mediated oxidative stress response via IPA® ENSG00000178573 ENSG00000177606 ENSG00000167996 ENSG00000125656 ENSG00000160783 ENSG00000111816 ENSG00000135624 ENSG00000156273 PMC6955783__F6 Hypothesized pathway and consequences of glutamine uptake in 2 h post METH STR microglia ENSG00000151012 ENSG00000103042 ENSG00000103064 ENSG00000111371 ENSG00000164294 ENSG00000115419 PMC2818736__F1 Colorectal cancer (CRC) stem cell model ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC5740974__F3 Cell entry and innate immune response ENSG00000172936 PMC3609760__F5 Transcriptional Profiling of Rice Early Response to Magnaporthe oryzae Identified OsWRKYs as Important Regulators in Rice Blast Resistance ENSG00000062485 ENSG00000084774 PMC3380573__F1 Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment ENSG00000169047 ENSG00000198793 ENSG00000155792 PMC5629314__F2 Pathway of de novo fatty acid synthesis in C ENSG00000083857 ENSG00000165323 PMC5629314__F6 Abbreviated pathway of prenol and sterol lipid synthesis in C ENSG00000132423 ENSG00000167113 ENSG00000119723 ENSG00000110871 ENSG00000173085 PMC8567165__F5 Proteomic identification of ruminal epithelial protein expression profiles in response to starter feed supplementation in pre-weaned lambs ENSG00000154553 ENSG00000133110 ENSG00000196923 ENSG00000148175 ENSG00000026508 ENSG00000172403 ENSG00000171863 ENSG00000116761 ENSG00000163631 PMC8745585__F1 Homologous Recombination Deficiencies and Hereditary Tumors ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000136492 ENSG00000083093 ENSG00000185379 ENSG00000182185 ENSG00000108384 ENSG00000121058 ENSG00000123374 ENSG00000051180 ENSG00000139618 PMC3484431__F9 Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma ENSG00000164690 ENSG00000100985 ENSG00000128602 PMC5685659__F7 Diagram showing LMP1 signaling transduction to IRF4 activation ENSG00000137265 PMC8226784__F10 Dihydroartemisinin Inhibits mTORC1 Signaling by Activating the AMPK Pathway in Rhabdomyosarcoma Tumor Cells ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC9135563__F5 Comprehensive Diagnostic Medical System Based on Notch1 Signaling Pathway to Inhibit the Growth of Small-Cell Lung Carcinoma ENSG00000142192 ENSG00000102172 PMC7690808__F3 TGFB targeting factors that “lock” NK cell functions ENSG00000198793 ENSG00000150637 PMC6826509__F4 Influence of high CO2 concentration on hormone and stomatal regulation ENSG00000108582 ENSG00000197429 ENSG00000062485 PMC9634419__F4 Human stefin B: from its structure, folding, and aggregation to its function in health and disease ENSG00000198793 ENSG00000168036 PMC6685084__F1 The genetics of human hematopoiesis and its disruption in disease PMC6525355__F1 Metabolic engineering strategies for producing PPD from xylose ENSG00000197429 ENSG00000158125 ENSG00000198947 PMC7690808__F1 Transforming growth factorB (TGFB) signalling pathways in tumorigenesis ENSG00000198793 PMC4804493__F3 Death receptor signaling in SIVA ENSG00000102871 ENSG00000082512 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC5360883__F1 Diagram summarizing the effects of effector proteins on inflammatory signaling pathways in host cells ENSG00000162711 ENSG00000102871 ENSG00000125538 ENSG00000149273 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000175104 ENSG00000127191 PMC8848739__F4 Case report of recurrent fibromatosis with laryngeal involvement: Treatment based on network analyses of NGS data ENSG00000139330 ENSG00000017797 ENSG00000162733 ENSG00000163462 ENSG00000105808 ENSG00000164088 ENSG00000105401 ENSG00000196361 ENSG00000030304 ENSG00000182255 ENSG00000185483 ENSG00000292357 PMC9297685__F4 Possible mechanisms of cardioprotection resulting from stimulation of insulin receptor family members ENSG00000177169 ENSG00000164430 PMC3684860__F7 Evolution of the Eye Transcriptome under Constant Darkness in Sinocyclocheilus Cavefish ENSG00000105392 ENSG00000114349 ENSG00000285493 ENSG00000048545 PMC5739070__F3 Optic Pathway Gliomas in Neurofibromatosis Type 1 ENSG00000291971 ENSG00000198793 PMC8785327__F4 Differential target multiplexed spinal cord stimulation programming modulates proteins involved in ion regulation in an animal model of neuropathic pain ENSG00000011677 ENSG00000291560 ENSG00000171723 ENSG00000092621 ENSG00000101438 ENSG00000157103 ENSG00000021645 ENSG00000135069 ENSG00000004939 PMC6693432__F5 Exploratory proteomic analysis implicates the alternative complement cascade in primary CNS vasculitis ENSG00000039537 ENSG00000009724 ENSG00000113600 ENSG00000291559 ENSG00000203710 ENSG00000000971 ENSG00000244731 ENSG00000120885 ENSG00000166278 ENSG00000117322 ENSG00000274619 ENSG00000196352 ENSG00000062485 PMC11822654__F2 Efferocytosis in immune cells ENSG00000153208 ENSG00000135218 ENSG00000120875 ENSG00000136997 ENSG00000073756 ENSG00000141968 ENSG00000183484 PMC7755516__F1 Intestinal epithelial cells (IECs) apoptosis in an acute and chronic state of intestinal diseases ENSG00000137275 ENSG00000109320 ENSG00000102871 ENSG00000082512 ENSG00000168040 ENSG00000127191 PMC4130902__F1 G-protein—coupled receptors, hedgehog signaling and primary cilia ENSG00000143147 ENSG00000164690 PMC9301190__F2 Role and Mechanisms of Tumor-Associated Macrophages in Hematological Malignancies ENSG00000182578 ENSG00000177575 ENSG00000108691 ENSG00000107562 ENSG00000138798 ENSG00000129226 ENSG00000121807 ENSG00000168610 ENSG00000121966 PMC4130902__F2 G-protein—coupled receptors, hedgehog signaling and primary cilia ENSG00000106571 ENSG00000173040 ENSG00000203965 ENSG00000164690 ENSG00000128602 PMC12108454__F1 Primary etiological factor for PMOP is estrogen deficiency ENSG00000281324 ENSG00000162337 ENSG00000167941 ENSG00000168036 PMC12108454__F2 New Perspectives on Postmenopausal Osteoporosis: Mechanisms and Potential Therapeutic Strategies of Sirtuins and Oxidative Stress ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000131196 ENSG00000143387 PMC12108454__F3 OS leads to the overproduction of ROS ENSG00000167468 ENSG00000077463 ENSG00000096717 ENSG00000142082 PMC3432093__F11 Resveratrol Inhibits LPS-Induced MAPKs Activation via Activation of the Phosphatidylinositol 3-Kinase Pathway in Murine RAW 264.7 Macrophage Cells ENSG00000125538 ENSG00000198793 ENSG00000096717 PMC3562715__F2 Oncogenic pathways in ABC-DLBCLThe stimulation of several surface receptors, including the B-cell receptor (BCR), CD40 or Toll-like receptors, triggers signaling cascades resulting in the activation of the NF-kB pathway ENSG00000105369 ENSG00000007312 ENSG00000137265 ENSG00000172936 ENSG00000198286 PMC11822654__F3 Impaired efferocytosis in aging ENSG00000167601 ENSG00000153208 ENSG00000092445 ENSG00000198053 ENSG00000272398 PMC5350184__F2 Genes involved in adipose tissue TLR‐ and insulin receptor signaling correlated with changes in plasma concentration of fetuin‐A and FFAs ENSG00000174123 ENSG00000243414 ENSG00000167207 ENSG00000196455 ENSG00000269335 ENSG00000095015 ENSG00000065559 ENSG00000185187 ENSG00000167965 ENSG00000150455 ENSG00000110057 ENSG00000127666 ENSG00000110719 ENSG00000114738 ENSG00000077150 ENSG00000148082 ENSG00000266173 ENSG00000263528 ENSG00000163131 ENSG00000157625 ENSG00000137161 ENSG00000164342 PMC5350184__F3 Genes involved in skeletal muscle TLR‐ and insulin receptor signaling related to changes in plasma concentration of fetuin‐A and FFAs ENSG00000174125 ENSG00000140992 ENSG00000243414 ENSG00000196455 ENSG00000115904 ENSG00000105647 ENSG00000121879 ENSG00000187840 ENSG00000102189 ENSG00000177189 ENSG00000185386 ENSG00000160867 ENSG00000162409 ENSG00000263528 ENSG00000156427 ENSG00000163131 ENSG00000106070 ENSG00000157625 PMC10854713__F3 Phosphorylation regulates EMT and other functions of CRC cells ENSG00000113384 ENSG00000160867 ENSG00000291971 ENSG00000134982 ENSG00000168036 ENSG00000107902 ENSG00000154310 ENSG00000103507 ENSG00000135424 ENSG00000125534 ENSG00000168610 ENSG00000173960 PMC7399071__F2 DNA repair pathways ENSG00000105486 ENSG00000132646 ENSG00000051180 PMC10854713__F5 Glycosylation regulates the metastasis of CRC cells ENSG00000147162 ENSG00000069482 ENSG00000085117 ENSG00000064225 ENSG00000198408 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000073849 PMC1435944__F6 Graphical Interface for the KnowledgeNet of candidate genes for hypertension ENSG00000051523 ENSG00000175206 ENSG00000169047 ENSG00000143839 ENSG00000159899 ENSG00000131910 ENSG00000073756 ENSG00000087460 ENSG00000120937 ENSG00000132170 ENSG00000108691 ENSG00000052344 ENSG00000196549 ENSG00000177674 ENSG00000151617 ENSG00000146648 PMC11475559__F3 RhoA is overexpressed in cancer and promotes cancer progression via RhoA/ROCK2 signaling pathway PMC3124103__F1 Transcription factor NFKB regulates the cellular response to inflammatory and oxidant stress, as well as stretch ENSG00000122194 PMC7530265__F9 The potential protective effects of PA in LPS-induced intestinal barrier dysfunction ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC9209463__F3 Effect of dietary soybean oil inclusion on liver-related transcription factors in a pig model for metabolic diseases ENSG00000140992 ENSG00000113070 ENSG00000163914 ENSG00000169710 ENSG00000112715 ENSG00000168610 ENSG00000146648 ENSG00000198286 PMC5828951__F2 Targeting Bromodomain and Extraterminal Proteins in Breast Cancer ENSG00000141867 ENSG00000198793 PMC3207219__F1 ROCK signaling pathway with focus on survival and regeneration ENSG00000242689 ENSG00000169783 ENSG00000198670 PMC9475465__F3 Immunosuppression in tumor immune microenvironment and its optimization from CAR-T cell therapy ENSG00000163464 PMC9209463__F2 Effect of dietary soybean oil inclusion on liver-related transcription factors in a pig model for metabolic diseases ENSG00000131473 ENSG00000160752 ENSG00000067064 ENSG00000110921 ENSG00000119915 ENSG00000112972 ENSG00000172893 ENSG00000186480 ENSG00000066322 ENSG00000169710 ENSG00000099194 PMC7521217__F10 Based on the findings from Figures  and , we summarized the proposed underlying mechanism of oxidative stress downstream signalling pathway participated in brain damage in setting of acute IS ENSG00000065833 ENSG00000113600 ENSG00000154920 PMC4569902__F7 Schematic view of the integration of Sema3-Nrp with the Hh signal pathway by controlling PKA and PDE4 ENSG00000164690 ENSG00000128602 ENSG00000113448 PMC6765251__F6 Putative metabolic map of a bacterium within the miscellaneous Bacteroidales metagenome reconstructed from the metagenomic data ENSG00000172005 ENSG00000145020 PMC3973656__F1 Curbing autophagy and histone deacetylases to kill cancer cells ENSG00000177169 ENSG00000144848 PMC12232871__F7 Some KRAS signaling pathways mediating PC mentioned in this review ENSG00000291971 ENSG00000288145 ENSG00000006451 ENSG00000144118 ENSG00000198793 ENSG00000136997 ENSG00000153574 ENSG00000173517 ENSG00000146648 PMC12232871__F8 Some p53, CDKN2A, and SMAD4 signaling pathways mediating PC mentioned in this review ENSG00000165119 ENSG00000135446 ENSG00000129514 ENSG00000105810 PMC6797860__F1 Receptor composition of IL-12 family members and related cytokines ENSG00000162594 ENSG00000096996 ENSG00000138378 ENSG00000115415 ENSG00000105246 ENSG00000119912 ENSG00000168610 PMC7890593__F3 Identifying AKAPs in Cells and Tissues ENSG00000075856 ENSG00000029363 ENSG00000124789 ENSG00000119707 ENSG00000109606 ENSG00000137807 ENSG00000085872 ENSG00000115524 ENSG00000175467 ENSG00000169813 ENSG00000054118 ENSG00000101191 ENSG00000164609 ENSG00000149503 PMC6912721__F6 Urea cycle and nitric oxide pathway ENSG00000081181 ENSG00000118520 ENSG00000036473 PMC8326113__F6 CXCL16 Promotes Gastric Cancer Tumorigenesis via ADAM10-Dependent CXCL16/CXCR6 Axis and Activates Akt and MAPK Signaling Pathways ENSG00000161921 ENSG00000137845 PMC9028856__F1 Autophagy Process in Cervical Carcinogenesis: Role of Non-Coding-RNAs, Molecular Mechanisms, and Therapeutic Targets ENSG00000177169 ENSG00000175634 ENSG00000198793 ENSG00000144848 ENSG00000284099 ENSG00000164327 ENSG00000197785 ENSG00000145782 ENSG00000057663 PMC12232871__F5 Underlying mechanisms of several potential PC therapeutics via proteomic approaches ENSG00000087245 ENSG00000151012 ENSG00000162433 ENSG00000163235 ENSG00000198793 ENSG00000137831 ENSG00000185591 ENSG00000164690 ENSG00000100985 PMC3155287__F1 Autophagy regulation ENSG00000198793 ENSG00000167965 PMC6776600__F1 Overview on complement activation and cascade progression ENSG00000134830 ENSG00000197405 PMC3268901__F1 The PTEN/mTOR signaling pathway ENSG00000163235 ENSG00000198793 PMC11019658__F3 Mechanisms by which DHM inhibits tumour cell invasion and metastasis ENSG00000170558 ENSG00000185591 PMC9841179__F5 Current understanding of the cGAS-STING signaling pathway: Structure, regulatory mechanisms, and related diseases ENSG00000183735 ENSG00000164430 ENSG00000171540 PMC1815248__F5 Co-option of a developmental pathway by invasive tumors ENSG00000087245 PMC11019658__F1 Mechanistically, DHM inhibits tumour cell proliferation ENSG00000189403 ENSG00000168610 ENSG00000121966 PMC9841179__F6 Current understanding of the cGAS-STING signaling pathway: Structure, regulatory mechanisms, and related diseases PMC11019658__F2 DHM induces apoptosis in tumour cells and induces the associated signalling pathway ENSG00000148400 ENSG00000198793 ENSG00000119912 ENSG00000026103 PMC5454035__F1 Regulation of autophagy by nutrients and hormones via the mammalian target of rapamycin (mTOR) signaling pathway ENSG00000175054 ENSG00000177169 ENSG00000123395 ENSG00000198382 ENSG00000083290 ENSG00000169047 PMC9406056__F1 Neurotransmitters: Potential Targets in Glioblastoma ENSG00000069482 ENSG00000146648 PMC6757296__F2 Exosomes secreted by MM, NSCLC and PCa tumors carry different and abundant contents, which serve a key role in osteoclasts or osteoblasts, resulting in different metastatic lesions ENSG00000109321 ENSG00000146648 PMC4822806__F3 Molecular mechanisms involved in autophagy and NAFLD.Notes: 1 ENSG00000198793 PMC2063536__F7 ES cell–based model describing the ontogeny of NSCs ENSG00000128342 ENSG00000120868 PMC4029773__F1 JAK-STAT signaling in adipose tissue function ENSG00000026103 PMC9841179__F3 Current understanding of the cGAS-STING signaling pathway: Structure, regulatory mechanisms, and related diseases ENSG00000183735 ENSG00000164430 PMC9841179__F4 Current understanding of the cGAS-STING signaling pathway: Structure, regulatory mechanisms, and related diseases ENSG00000177169 ENSG00000112343 ENSG00000119401 ENSG00000204977 ENSG00000137699 ENSG00000292211 ENSG00000120885 ENSG00000169871 ENSG00000196396 ENSG00000101557 ENSG00000090432 ENSG00000183735 ENSG00000171720 ENSG00000164430 ENSG00000135912 ENSG00000138468 ENSG00000170703 ENSG00000172977 ENSG00000157450 ENSG00000173456 PMC10139189__F1 Migration and invasion of GBM cells is related to the inherent capacity and the cellular interactions that occur on the migratory front ENSG00000168329 ENSG00000133937 ENSG00000170558 ENSG00000026508 ENSG00000128342 ENSG00000091879 ENSG00000277641 ENSG00000121966 PMC7481416__F3 Different pathways in cancer targeted by p-PROTAC ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC6539103__F2 Potential roles of aberrant activations of MAPK and PI3K signaling pathways in pathogenesis of PWS/SWS ENSG00000159224 ENSG00000291971 ENSG00000198793 PMC2900889__F8 Possible fates of disulfide reduced SOD1 in the G93A/CCS mouse ENSG00000173992 ENSG00000062485 PMC2966065__F1 Chemical structure of OHyW in tRNAPhe and its biosynthetic pathway ENSG00000145321 ENSG00000198874 ENSG00000162971 PMC6915928__F2 The results of protein-protein interactions were identified with STRING database ENSG00000174123 ENSG00000139193 ENSG00000081237 ENSG00000198851 ENSG00000122224 ENSG00000095585 ENSG00000075884 ENSG00000117091 ENSG00000102245 ENSG00000166501 ENSG00000104894 ENSG00000015285 ENSG00000165409 ENSG00000113263 ENSG00000288169 ENSG00000115165 ENSG00000100079 PMC5658094__F6 Brominated indoles from a marine mollusc inhibit inflammation in a murine model of acute lung injury ENSG00000172936 ENSG00000136869 PMC4593030__F7 Lysine Methyltransferase SETD7 (SET7/9) Regulates ROS Signaling through mitochondria and NFE2L2/ARE pathway ENSG00000109819 ENSG00000116044 ENSG00000145391 PMC8070205__F5 Activation of canonical STING Pathway upon replication stress or DNA damage ENSG00000149311 ENSG00000012048 ENSG00000183735 ENSG00000164430 ENSG00000051180 PMC7593846__F7 Signaling pathway analysis based on the potential biomarkers (A) Summary of ingenuity pathway analysis with MetaboAnalyst ENSG00000152266 ENSG00000154059 PMC8070205__F2 Homologous-directed repair ENSG00000012048 ENSG00000083093 ENSG00000138346 ENSG00000178295 ENSG00000188827 ENSG00000165392 ENSG00000145321 ENSG00000175643 ENSG00000197299 ENSG00000051180 ENSG00000178966 ENSG00000139618 PMC6689035__F7 Optineurin downregulation induces endoplasmic reticulum stress, chaperone-mediated autophagy, and apoptosis in pancreatic cancer cells ENSG00000123240 ENSG00000128272 ENSG00000005893 ENSG00000198890 PMC8637646__F2 Metabolic therapy and bioenergetic analysis: The missing piece of the puzzle ENSG00000198793 ENSG00000136997 ENSG00000111371 ENSG00000078237 ENSG00000103257 ENSG00000106459 PMC7017004__F1 Signal transducers and activators of transcription (STAT)3 and STAT5 signaling in epithelial ovarian cancer (EOC) and tumor microenvironment ENSG00000196090 ENSG00000128342 PMC8070205__F8 Progerin expression in HGPS leads to DNA repair defect, replicative stress, and inflammation through DNA sensing in the cytosol ENSG00000012048 ENSG00000164430 ENSG00000080345 ENSG00000115415 ENSG00000132646 ENSG00000051180 PMC6387042__F1 Mammalian or mechanistic target of rapamycin (mTOR) complexes and signaling pathway of mTORC1 and mTORC2 ENSG00000101407 ENSG00000163435 ENSG00000106070 ENSG00000155792 ENSG00000168610 PMC7755516__F2 Lytic cell death pathways of intestinal epithelial cells (IECs) during the intestinal diseases ENSG00000278718 ENSG00000162711 ENSG00000137275 ENSG00000167468 ENSG00000125538 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC2754932__F6 Model of Udu function in DNA damage response ENSG00000149311 ENSG00000112118 PMC8228377__F1 Examination of the APOBEC3 Barrier to Cross Species Transmission of Primate Lentiviruses ENSG00000183978 ENSG00000154582 PMC7027041__F8 Signaling pathways under heat stress affecting bGCs functions: A network map of pathways significantly (P < 0.05) enriched after heat stress ENSG00000174156 ENSG00000064490 ENSG00000242110 ENSG00000197728 ENSG00000089157 ENSG00000138326 ENSG00000118971 ENSG00000166851 ENSG00000164305 ENSG00000077150 ENSG00000073060 ENSG00000138764 ENSG00000169750 ENSG00000177519 ENSG00000288141 ENSG00000178828 ENSG00000126458 ENSG00000185825 ENSG00000137547 ENSG00000171421 ENSG00000103066 ENSG00000112964 ENSG00000243147 ENSG00000144455 ENSG00000142534 ENSG00000127191 ENSG00000111725 ENSG00000174748 ENSG00000132646 ENSG00000088298 ENSG00000066136 ENSG00000111670 ENSG00000186469 PMC6044348__F1 Schematic illustrating the current working hypothesis on IFNT signaling in endometrial epithelia and stroma of the ovine uterus ENSG00000213928 ENSG00000187608 ENSG00000175315 ENSG00000115267 ENSG00000273686 ENSG00000125347 ENSG00000073756 ENSG00000134321 ENSG00000105397 ENSG00000003989 ENSG00000115415 ENSG00000146678 ENSG00000168310 PMC8205988__F1 Anti- or pro-tumorigenic function of adiponectin in colon cancer ENSG00000163739 ENSG00000198793 ENSG00000159346 ENSG00000285070 PMC9669913__F6 Eupatilin attenuates the senescence of nucleus pulposus cells and mitigates intervertebral disc degeneration via inhibition of the MAPK/NFKB signaling pathway ENSG00000139219 ENSG00000125398 PMC8415555__F9 Effect of tonB Gene on the Virulence of Pseudomonas plecoglossicida and the Immune Response of Epinephelus coioides ENSG00000062485 ENSG00000084774 PMC9298504__F1 Targeting Macroautophagy as a Therapeutic Opportunity to Treat Parkinson’s Disease ENSG00000177169 ENSG00000110497 ENSG00000152348 ENSG00000162711 ENSG00000123395 ENSG00000198382 ENSG00000083290 ENSG00000198793 ENSG00000155792 ENSG00000158828 ENSG00000069329 ENSG00000116675 ENSG00000141564 ENSG00000167965 ENSG00000171791 ENSG00000010310 ENSG00000057663 ENSG00000144848 ENSG00000204673 ENSG00000145782 PMC7136955__F1 Cancer‐associated fibroblasts: activin A adds another string to their bow PMC4183996__F4 Involvement of microRNAs (miRNAs) in epithelial-mesenchymal transition (EMT)-related metastasis ENSG00000019991 ENSG00000169554 ENSG00000138798 ENSG00000170558 ENSG00000168036 PMC7408135__F2 Ether phospholipid synthesis pathway in peroxisomes ENSG00000116906 ENSG00000197601 PMC8372757__F4 Differential regulation of cerebral microvascular transcription by single and repetitive hypoxic conditioning ENSG00000291971 ENSG00000134070 ENSG00000091879 ENSG00000175104 ENSG00000124762 PMC8372757__F5 Differential regulation of cerebral microvascular transcription by single and repetitive hypoxic conditioning ENSG00000177455 ENSG00000108839 ENSG00000162711 ENSG00000111537 ENSG00000002330 ENSG00000197635 ENSG00000134982 ENSG00000186716 ENSG00000198793 ENSG00000110651 ENSG00000124762 PMC6160013__F8 Anti-oxidant activity of GPx3 mediating lung cancer suppression ENSG00000211445 ENSG00000134057 ENSG00000138798 ENSG00000146648 PMC7761761__F8 Putative metabolic pathway for the production of derivatives of nitrogen-containing azaphilone red pigments in the marine-derived Talaromyces sp ENSG00000184357 ENSG00000167434 PMC5218767__F1 Defective Treg cell suppressive mechanisms in IPEX and IPEX-like disorders ENSG00000134982 ENSG00000163599 ENSG00000198589 ENSG00000049768 PMC11978843__F6 Analysis of DEGs related to energy metabolism, phytohormone synthesis, and signaling pathway ENSG00000180210 ENSG00000117525 ENSG00000198734 ENSG00000084774 PMC6727143__F3 Ingenuity pathway analysis representation of the most significant pathway in ICH versus CTRL – T cell receptor signaling ENSG00000107338 ENSG00000010810 ENSG00000163599 ENSG00000113263 ENSG00000135605 PMC6999830__F1 Mitochondria as a regulator of inflammation ENSG00000162711 ENSG00000088888 ENSG00000125538 ENSG00000175104 PMC7503245__F8 Schematic presentation of the possible role of bone kynurenic pathway activation in the osteoblast maturation process ENSG00000128272 ENSG00000242252 ENSG00000167941 PMC8636667__F4 Biocompatibility pathways and mechanisms for bioactive materials: The bioactivity zone ENSG00000169291 ENSG00000005882 ENSG00000010810 PMC8658259__F4 Integrated or Independent Actions of Metformin in Target Tissues Underlying Its Current Use and New Possible Applications in the Endocrine and Metabolic Disorder Area ENSG00000291972 ENSG00000138798 ENSG00000198793 ENSG00000162772 ENSG00000168610 PMC8636667__F1 Biocompatibility pathways and mechanisms for bioactive materials: The bioactivity zone ENSG00000090402 ENSG00000175104 ENSG00000131196 PMC8392326__F2 Inborn Errors in the LRR Domain of Nod2 and Their Potential Consequences on the Function of the Receptor ENSG00000088888 ENSG00000167207 ENSG00000131323 PMC7460564__F3 Enzymatic activity of prolidase affects various cellular processes ENSG00000198793 ENSG00000100033 PMC4595774__F1 Regulation of the Golgi via the GOLPH3 pathway ENSG00000113384 ENSG00000143457 PMC1356334__F7 Alignment of sequences adjacent to Y200 for human TRPV1–4 ENSG00000291971 ENSG00000196689 PMC3676171__F2 Bile acid synthesis, conjugation, and biotransformation ENSG00000276559 ENSG00000135929 PMC7851184__F2 Proposed mechanisms of neoplastic transformation of small intestinal ILCs in refractory CD II ENSG00000148400 ENSG00000132646 ENSG00000164136 ENSG00000049768 PMC7312214__F1 Innovative Potential of Statins in Cancer: New Targets for New Therapies ENSG00000135446 ENSG00000198793 ENSG00000163914 ENSG00000136997 ENSG00000197429 ENSG00000164690 ENSG00000171791 ENSG00000100985 PMC6193418__F1 Cell‐intrinsic pathway of apoptosis ENSG00000120868 ENSG00000171791 PMC3356019__F1 Emerging pharmacological strategies for CSCs targeting include self-renewal pathway antagonists and chemoresistance-reverting agents ENSG00000168036 ENSG00000128602 PMC6598962__F6 Cooperation of 17-aminogeldanamycin (AG) and trametinib (TRA) or vemurafenib (PLX) a A schematic summary of molecular effects of TRA, and PLX activity, and 17-aminogeldanamycin-mediated HSP90 inhibition in melanoma cells ENSG00000143486 ENSG00000128272 ENSG00000157764 ENSG00000144895 ENSG00000100219 PMC4404315__F3 Embryonic Stem Cell Self-Renewal ENSG00000159128 ENSG00000213928 ENSG00000005339 ENSG00000112964 ENSG00000099985 ENSG00000242689 ENSG00000119535 ENSG00000291971 ENSG00000137070 ENSG00000114737 ENSG00000033800 ENSG00000137193 ENSG00000027697 ENSG00000103522 ENSG00000292363 ENSG00000187266 ENSG00000175505 ENSG00000174564 ENSG00000142166 ENSG00000150281 ENSG00000145623 ENSG00000128342 ENSG00000115145 ENSG00000016402 PMC6078129__F1 Programmed cell death: the battlefield between the host and alpha-herpesviruses and a potential avenue for cancer treatment ENSG00000006712 ENSG00000102871 ENSG00000168040 ENSG00000026103 PMC6078129__F2 Programmed cell death: the battlefield between the host and alpha-herpesviruses and a potential avenue for cancer treatment ENSG00000168040 ENSG00000168404 ENSG00000026103 PMC12038969__F4 Correlation between PYGO2 and IL10 expression through the Wnt/Beta-catenin signaling pathway in ESCC progression ENSG00000134982 ENSG00000168036 ENSG00000146648 PMC4404315__F2 Embryonic Stem Cell Self-Renewal ENSG00000066468 ENSG00000160867 ENSG00000291971 ENSG00000077782 PMC2679749__F3 Control of autophagy ENSG00000144895 ENSG00000198793 ENSG00000205250 PMC7887427__F7 Differential gene expression of EGFR pathway proteins in TPC1-deficient MEF cells compared with wild-type cellsColor code indicates gradual changes in expression ENSG00000133056 ENSG00000070831 ENSG00000291971 ENSG00000198793 ENSG00000095015 ENSG00000115904 ENSG00000065559 ENSG00000168036 ENSG00000108443 ENSG00000168610 ENSG00000141968 ENSG00000160691 ENSG00000110395 ENSG00000148660 ENSG00000115415 ENSG00000149269 ENSG00000163914 ENSG00000263528 ENSG00000145349 ENSG00000146648 PMC1502426__F1 Chromophore regeneration in vertebrate and invertebrate photoreceptors ENSG00000121207 ENSG00000116745 ENSG00000197713 PMC3469471__F2 Regulation of the human TRAIL gene ENSG00000168040 PMC2926258__F3 Schematic representation of the role of T cells in the mechanism by which intermittent PTH treatment stimulates bone formation ENSG00000152266 ENSG00000281324 ENSG00000162337 ENSG00000134569 ENSG00000169884 PMC3355932__F2 Anaplastic lymphoma kinase signaling ENSG00000002330 ENSG00000291971 ENSG00000198793 ENSG00000105639 PMC2850388__F7 Dkk4 and Eda Regulate Distinctive Developmental Mechanisms for Subtypes of Mouse Hair ENSG00000138795 ENSG00000155011 ENSG00000104371 ENSG00000168036 ENSG00000164690 ENSG00000203883 PMC11761272__F6 Protective effect of HDH against IAV via activation of the innate immune system ENSG00000213928 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000142082 ENSG00000172183 ENSG00000142166 PMC8972670__F1 Characteristics of NLRs ENSG00000162711 ENSG00000167207 ENSG00000281166 ENSG00000091592 PMC6314075__F2 Nuclear factor of activated T cell (NFAT)c1-centered osteoclastogenic signaling network ENSG00000170909 ENSG00000101307 ENSG00000164935 ENSG00000137872 ENSG00000175104 ENSG00000131196 ENSG00000135605 ENSG00000010671 ENSG00000075213 PMC4019002__F1 Omega-3 fatty acids and dementia ENSG00000171105 ENSG00000002330 ENSG00000005882 ENSG00000119912 PMC12116884__F9 PF ameliorates neuroinflammation induced by ABO ENSG00000129226 ENSG00000118520 ENSG00000102003 PMC8870839__F2 Iron in Porphyrias: Friend or Foe? ENSG00000110711 ENSG00000080819 ENSG00000126088 ENSG00000158578 ENSG00000188690 PMC9126665__F10 Dl-3-n-Butylphthalide Improves Neuroinflammation in Mice with Repeated Cerebral Ischemia-Reperfusion Injury through the Nrf2-Mediated Antioxidant Response and TLR4/MyD88/NFKB Signaling Pathway ENSG00000099721 ENSG00000172936 ENSG00000136869 ENSG00000023909 ENSG00000079999 PMC5398616__F3 Genome-wide association studies identified multiple genetic loci for body size at four growth stages in Chinese Holstein cattle ENSG00000177485 ENSG00000170027 ENSG00000196367 PMC3478427__F2 Metabolic Actions of Angiotensin II and Insulin: A Microvascular Endothelial Balancing Act ENSG00000228716 PMC4178426__F9 Vascular smooth muscle contraction pathway ENSG00000213658 ENSG00000162924 PMC3478427__F3 Metabolic Actions of Angiotensin II and Insulin: A Microvascular Endothelial Balancing Act PMC4178426__F6 Cell cycle pathway ENSG00000172005 ENSG00000105656 PMC3564914__F1 Transcriptome analysis of bitter acid biosynthesis and precursor pathways in hop (Humulus lupulus) ENSG00000060982 ENSG00000197429 ENSG00000105552 PMC5536301__F7 Chicken hepatic response to chronic heat stress using integrated transcriptome and metabolome analysis ENSG00000049239 PMC5955138__F1 Natural product based sensitization of GBM ENSG00000002330 ENSG00000150907 ENSG00000170430 PMC7533754__F1 Mechanisms involved in gut microbiota-host communication ENSG00000162711 ENSG00000049768 PMC10150895__F2 Emerging role of long non-coding RNA JPX in malignant processes and potential applications in cancers ENSG00000122691 ENSG00000170558 ENSG00000198793 ENSG00000145321 ENSG00000124766 ENSG00000168036 ENSG00000112715 ENSG00000118971 PMC8669998__F1 Type I Interferon and the Spectrum of Susceptibility to Viral Infection and Autoimmune Disease: A Shared Genomic Signature ENSG00000213928 ENSG00000276561 ENSG00000142166 ENSG00000183735 ENSG00000239732 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC4745742__F8 Deoxypodophyllotoxin suppresses tumor vasculature in HUVECs by promoting cytoskeleton remodeling through LKB1-AMPK dependent Rho A activation ENSG00000163914 ENSG00000143196 PMC8860897__F1 Immune Checkpoint Inhibitors in Tumors Harboring Homologous Recombination Deficiency: Challenges in Attaining Efficacy ENSG00000198053 ENSG00000115415 ENSG00000125347 ENSG00000168610 PMC12041090__F3 Mechanisms by which natural products ameliorate renal fibrosis ENSG00000177169 ENSG00000110497 ENSG00000124256 ENSG00000281324 ENSG00000162337 ENSG00000155792 ENSG00000168036 ENSG00000171791 ENSG00000142082 ENSG00000105639 ENSG00000276561 ENSG00000188818 ENSG00000277943 ENSG00000159714 ENSG00000183735 ENSG00000164430 ENSG00000214160 ENSG00000136869 ENSG00000096717 PMC8589249__F1 CCR7 in Blood Cancers – Review of Its Pathophysiological Roles and the Potential as a Therapeutic Target ENSG00000137077 ENSG00000197943 ENSG00000126353 ENSG00000010671 PMC6438423__F4 Analysis of the PI3K/AKT signaling pathway based on the KEGG database ENSG00000103479 ENSG00000105401 ENSG00000198793 ENSG00000136997 ENSG00000169032 PMC12041090__F2 TGFB/Smads signaling pathway ENSG00000115415 ENSG00000134982 ENSG00000198742 ENSG00000198793 ENSG00000156574 ENSG00000168036 ENSG00000105639 ENSG00000168610 PMC11035622__F8 Mitochondrial enzyme FAHD1 reduces ROS in osteosarcoma ENSG00000131473 ENSG00000122966 ENSG00000173599 ENSG00000172005 ENSG00000122696 ENSG00000115419 PMC6679203__F1 Signaling in AML FLT3-ITD ENSG00000122025 ENSG00000002330 ENSG00000198793 PMC8901701__F1 Immunopathology and Immunotherapy of Inflammatory Skin Diseases ENSG00000162594 ENSG00000105397 ENSG00000163739 ENSG00000169429 ENSG00000168610 ENSG00000115009 ENSG00000112486 PMC3942542__F1 Cyclic adenosine diphosphate ribose mediated Ca2+signaling ENSG00000167323 PMC6948255__F6 Silencing of Long Non-coding RNA HOTTIP Reduces Inflammation in Rheumatoid Arthritis by Demethylation of SFRP1 ENSG00000149968 ENSG00000168036 ENSG00000104332 PMC5877599__F4 Wnt and other signaling pathways regulating pluripotency of stem cells ENSG00000087095 ENSG00000084093 ENSG00000156574 ENSG00000167074 ENSG00000168610 ENSG00000071564 ENSG00000136603 ENSG00000143768 ENSG00000095739 ENSG00000147869 ENSG00000167941 ENSG00000128342 ENSG00000114315 ENSG00000127948 PMC5877599__F5 Hippo signaling pathway ENSG00000170365 ENSG00000126016 ENSG00000109321 ENSG00000150457 ENSG00000081051 ENSG00000132849 ENSG00000168646 ENSG00000131023 ENSG00000169435 ENSG00000140807 PMC8692906__F2 Topical application of TAK1 inhibitor encapsulated by gelatin particle alleviates corneal neovascularization ENSG00000138346 ENSG00000118007 ENSG00000108055 ENSG00000179091 ENSG00000091651 ENSG00000073111 ENSG00000277273 ENSG00000166851 ENSG00000117399 ENSG00000093009 ENSG00000145604 ENSG00000105486 ENSG00000101972 ENSG00000132646 ENSG00000172005 ENSG00000115942 ENSG00000135336 ENSG00000123374 PMC6863919__F5 Metabolic reconstruction of “Ca ENSG00000197429 PMC5992490__F2 Actions of IGF-1 and angiotensin II in skeletal muscle ENSG00000002330 ENSG00000140443 PMC7327986__F5 NRF2 signaling pathway in the context of environmental pollutants induced redox toxicity and its regulation ENSG00000284774 ENSG00000146648 ENSG00000079999 PMC4394695__F1 Nuclear distribution of the PI3K pathway ENSG00000117020 ENSG00000151151 PMC3704172__F3 miR-181b and miR-146a induced in CAFs are involved in the regulation of the NFKB signaling pathway ENSG00000175104 ENSG00000168610 ENSG00000184216 PMC6428526__F3 EMT is Modulated by Multiple Cascades Through Several Networks ENSG00000170558 ENSG00000096717 ENSG00000099381 PMC8979689__F6 Folecitin Isolated from Hypericum oblongifolium Exerts Neuroprotection against Lipopolysaccharide-Induced Neuronal Synapse and Memory Dysfunction via p-AKT/Nrf-2/HO-1 Signalling Pathway ENSG00000102003 PMC8330071__F8 TLR7/8 signalling affects X-sperm motility via the GSK3 A/Beta-hexokinase pathway for the efficient production of sexed dairy goat embryos ENSG00000175104 ENSG00000105723 PMC2848307__F1 Survival pathways with their cross-talk and immune regulatory mechanisms are shown in this pictorial representation of the Reed-Sternberg (R-S) cell ENSG00000291971 ENSG00000198793 ENSG00000136997 ENSG00000158825 ENSG00000168610 PMC4086757__F1 Classification of resistance mechanisms to BRAF inhibitors ENSG00000157764 ENSG00000135446 ENSG00000198793 ENSG00000140443 PMC4281955__F1 Telling the story of a gastric cancer through sequencing and functional studies ENSG00000066468 ENSG00000179242 ENSG00000170558 PMC3659509__F1 Intracellular effects of soluble mediators are mainly mediated through the interaction with specific receptors that link extracellular signals up to modulation of gene expression ENSG00000150907 ENSG00000182759 ENSG00000146648 PMC2912204__F1 PIK3CA and KRAS mutations predict for response to everolimus therapy: now that’s RAD001 ENSG00000198793 PMC6830079__F1 Cyclic GMP AMP synthase-STING (cGAS-STING) pathway signaling as activated by genomic instability ENSG00000104856 ENSG00000183735 ENSG00000164430 ENSG00000173039 PMC6830079__F3 Two faces of cGAS-STING signaling in cancer ENSG00000169245 ENSG00000108691 ENSG00000164430 ENSG00000115415 ENSG00000134982 ENSG00000168610 PMC7057487__F3 Conceptualized network for the 7 enriched neurotransmission pathways ENSG00000136546 ENSG00000091664 ENSG00000144285 ENSG00000184156 ENSG00000157764 ENSG00000078369 ENSG00000050748 ENSG00000106688 ENSG00000115896 ENSG00000058668 ENSG00000157103 ENSG00000120251 ENSG00000162104 ENSG00000163873 PMC4652019__F1 TLR4 signaling in obesity ENSG00000167461 ENSG00000172936 ENSG00000136869 PMC6086983__F4 Scheme of the mechanism by which pioglitazone (PIO) regulates hepatic metabolites, lipids and related gene‐expression patterns (italicized) ENSG00000135218 ENSG00000042832 ENSG00000173599 ENSG00000111684 ENSG00000062282 ENSG00000102977 ENSG00000026103 PMC7956931__F2 Simplified overview of EGFR pathway, with numbers of studies included per EGFR pathway inhibitor target ENSG00000157764 ENSG00000198793 ENSG00000146648 PMC2787898__F1 TRIF-dependent signaling pathway is not required for acute cerebral ischemia/reperfusion injury in mice ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC11870265__F5 MAPK signaling pathways, their activators, and inhibitorsrelevant to this study ENSG00000138798 ENSG00000146648 PMC7363118__F12 RIG-I–like receptor directs antiviral responses to a bunyavirus and is antagonized by virus-induced blockade of TRIM25-mediated ubiquitination ENSG00000183735 ENSG00000088888 ENSG00000121060 PMC11911240__F4 Regulation and Function of the cGAS-STING Pathway: Mechanisms, Post-Translational Modifications, and Therapeutic Potential in Immunotherapy ENSG00000292096 ENSG00000183735 ENSG00000164430 ENSG00000112343 ENSG00000244038 ENSG00000137699 ENSG00000126457 ENSG00000099864 ENSG00000159335 PMC1483149__F1 Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony ENSG00000198793 ENSG00000173599 ENSG00000026103 PMC11911240__F1 CGAS-STING-TBK1 signaling pathway ENSG00000104856 ENSG00000183735 ENSG00000164430 ENSG00000173039 PMC12116456__F3 VEGF-A/VEGFR2 axis drives HB pathogenesis via angiogenesis stimulation ENSG00000291971 ENSG00000198793 ENSG00000112715 PMC8714735__F3 IL-6/STAT3 Is a Promising Therapeutic Target for Hepatocellular Carcinoma ENSG00000119888 ENSG00000291971 ENSG00000272398 ENSG00000081051 ENSG00000168610 ENSG00000121966 PMC11276702__F7 Gene expression of plant hormone biosynthesis pathway in the intraspecific hybrid fruit of H ENSG00000090402 PMC8956559__F4 Adipose tissue: a neglected organ in the response to severe trauma? ENSG00000274619 ENSG00000125538 ENSG00000189403 PMC8637576__F6 Sustained compensatory p38 MAPK signaling following treatment with MAPK inhibitors induces the immunosuppressive protein CD73 in cancer: combined targeting could improve outcomes ENSG00000019991 ENSG00000100422 ENSG00000111537 PMC2614485__F6 A simplified Hh signaling pathway, constructed from combined Drosophila and mammalian data ENSG00000180447 ENSG00000157933 ENSG00000128602 PMC7913072__F4 Evasion of apoptosis by myofibroblasts: a hallmark of fibrotic diseases ENSG00000002330 ENSG00000105329 ENSG00000168036 ENSG00000168040 PMC4707055__F2 CO2 sensing and CO2 regulation of stomatal conductance: advances and open questions ENSG00000167434 PMC8571860__F6 Wheat transcriptome profiling reveals abscisic and gibberellic acid treatments regulate early-stage phytohormone defense signaling, cell wall fortification, and metabolic switches following Fusarium graminearum-challenge ENSG00000110934 ENSG00000113161 PMC2797318__F2 Promising bone-related targets for rheumatoid arthritis therapy ENSG00000170365 ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11064406__F3 Intracellular copper distribution pathways ENSG00000173992 ENSG00000138495 ENSG00000123191 ENSG00000177556 PMC10609905__F1 Vitamin D synthesis pathway ENSG00000111012 ENSG00000109061 ENSG00000019186 PMC10604974__F3 Activation mechanism of the NLRP3 inflammasome ENSG00000278718 ENSG00000162711 ENSG00000088888 ENSG00000172936 PMC10604974__F2 Autophagy in viral infection ENSG00000177169 ENSG00000110497 ENSG00000152348 ENSG00000123395 ENSG00000083290 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC3889557__F10 Schematic representation of eHsp90A signaling pathway PMC9699419__F2 Cluster C19MC in Pre-Eclampsia Development ENSG00000162711 ENSG00000087245 ENSG00000118503 ENSG00000124875 PMC7880238__F1 Key signals regulating YAP/TAZ activity ENSG00000126016 ENSG00000149930 ENSG00000160551 ENSG00000135090 ENSG00000291971 ENSG00000197905 ENSG00000168067 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 ENSG00000104814 ENSG00000186575 ENSG00000011566 ENSG00000163914 PMC6685594__F4 lncRNAs mediate drug and radiation resistance ENSG00000177169 ENSG00000125398 ENSG00000163235 ENSG00000105991 ENSG00000198793 ENSG00000168036 ENSG00000168610 ENSG00000146648 ENSG00000140443 PMC7786191__F2 UPRER and UPRmt mechanistic commonalities and differences are described in this figure ENSG00000144895 ENSG00000169136 ENSG00000100219 ENSG00000125656 PMC7880238__F2 Proposed strategies and small molecules (direct and indirect) that could promote or inhibit YAP/TAZ activity ENSG00000164879 ENSG00000126016 ENSG00000104814 ENSG00000011566 ENSG00000291971 ENSG00000144560 ENSG00000141639 ENSG00000168067 ENSG00000150457 ENSG00000131023 PMC11095602__F2 Senescence-associated lymphoma progression and drug resistance ENSG00000285109 ENSG00000198793 ENSG00000136997 ENSG00000172936 ENSG00000105639 ENSG00000168610 ENSG00000010671 PMC5296610__F4 Most significantly relevant pathways and highly linked molecules relevant to the merged bionetwork ENSG00000188822 ENSG00000187017 ENSG00000026103 PMC6033972__F2 Canonical and non-canonical signaling of interferon-gamma ENSG00000111537 ENSG00000020633 ENSG00000099942 ENSG00000168610 PMC9062079__F2 Lens Aquaporins in Health and Disease: Location is Everything! ENSG00000143867 ENSG00000196689 PMC4700229__F1 Interactions between immunotherapy and targeted therapy ENSG00000134982 ENSG00000198793 ENSG00000146648 PMC9076866__F8 Mechanism by which Grem1 regulates the TGFB1/Smad2/3 signaling pathway in IVDD PMC9610147__F1 Innate immune responses by rabies virus ENSG00000183735 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000168310 ENSG00000125347 ENSG00000276561 ENSG00000140464 PMC5479833__F4 Current model for selective compound families to promote neuronal compensation in HD via a stress response system centered onto FOXO and its co-factors ENSG00000145632 ENSG00000099985 ENSG00000129167 ENSG00000168036 ENSG00000144224 ENSG00000134595 ENSG00000132964 ENSG00000096717 PMC8391764__F2 Platelets, Not an Insignificant Player in Development of Allergic Asthma ENSG00000087245 ENSG00000137033 ENSG00000145777 ENSG00000100985 ENSG00000163737 ENSG00000106546 PMC4117150__F3 The Sonic Hedghehog (Shh) signalling pathway: Activation of signalling pathway is connected to various transmembrane proteins (Ptc, Smo), transcription factors (Ci/Gli) and protein kinases (Su(fu), fu) (Reproduced with permissions from Reference 31) ENSG00000164690 ENSG00000128602 PMC11064406__F4 Molecular mechanisms of cuproptosis ENSG00000121897 ENSG00000138495 ENSG00000123191 ENSG00000137714 PMC2712626__F1 The Double Life of Irs ENSG00000042832 ENSG00000150907 ENSG00000169047 PMC9556833__F4 Ubiquitin-like processing of TUG proteins as a mechanism to regulate glucose uptake and energy metabolism in fat and muscle ENSG00000169047 ENSG00000136111 ENSG00000107669 ENSG00000160999 PMC3376640__F6 Proposed Model of Psoriasis Pathogenesis in the Presence of Psoriasis-Specific CARD14 AlterationsAfter an inflammatory trigger, alterations in CARD14 induce activation of NF-kB ENSG00000141527 ENSG00000131323 ENSG00000136695 ENSG00000127191 ENSG00000115009 PMC9519816__F2 Exploring the role of Nrf2 signaling in glioblastoma multiforme ENSG00000181019 ENSG00000178573 ENSG00000177606 ENSG00000079999 PMC3711071__F1 Function and regulation of AMPK leading to tumor suppression ENSG00000177169 ENSG00000083290 ENSG00000198793 PMC6960354__F1 Kynurenine pathway of tryptophan metabolism ENSG00000111537 PMC12111917__F7 Signaling pathways activated by exogenous sVASN treatment in different cell types ENSG00000073350 ENSG00000044115 ENSG00000130702 ENSG00000184349 ENSG00000105499 ENSG00000132849 ENSG00000142166 ENSG00000145431 ENSG00000170365 ENSG00000148498 ENSG00000145623 ENSG00000184384 ENSG00000077782 ENSG00000113645 ENSG00000182578 ENSG00000126016 ENSG00000104365 ENSG00000171105 ENSG00000109320 ENSG00000007866 ENSG00000018408 ENSG00000169242 ENSG00000164171 ENSG00000168610 ENSG00000066468 ENSG00000123143 ENSG00000114315 ENSG00000146648 PMC7310537__F6 Phosphorylation of HH pathway components after 15 min treatment ENSG00000138002 ENSG00000187535 ENSG00000198793 ENSG00000159352 ENSG00000148384 ENSG00000108671 ENSG00000128602 ENSG00000281857 ENSG00000173692 PMC3149747__F2 Extensive feedback and feedforward loops between Ras signaling and miRNAs ENSG00000136158 ENSG00000164056 ENSG00000143878 ENSG00000159388 ENSG00000169047 ENSG00000136997 ENSG00000120868 ENSG00000124782 PMC3553295__F3 Cocaine and Withdrawal on the Mouse Nucleus Accumbens Transcriptome ENSG00000076864 ENSG00000005339 PMC11657697__F2 Inflammasomes in the three stages of HSCT Mobilization ENSG00000278718 ENSG00000163220 ENSG00000189403 ENSG00000162692 ENSG00000121966 PMC11657697__F3 Correlation between inflammasomes and HSCT ENSG00000026103 PMC4777846__F7 Schematic diagram of LRP1/Wnt5a-dependent inhibition of intracellular cholesterol accumulation ENSG00000160179 ENSG00000144959 PMC11657697__F1 Inflammasomes are multiprotein complexes composed of several domains with distinct functions ENSG00000278718 ENSG00000162711 ENSG00000163220 ENSG00000163568 ENSG00000163914 ENSG00000174885 ENSG00000091592 ENSG00000189403 ENSG00000091106 PMC6763609__F11 DEGs are potentially related to Alzheimer’s relevant pathways and functions ENSG00000196136 ENSG00000144285 ENSG00000291560 ENSG00000145681 ENSG00000128918 ENSG00000196549 ENSG00000172009 ENSG00000108813 ENSG00000119125 PMC6373781__F8 The interactions involved in the alteration of DC function following exposure to F ENSG00000132478 ENSG00000112149 PMC2994781__F1 Crystal Structure of the 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase•Dihydropteroate Synthase Bifunctional Enzyme from Francisella tularensis ENSG00000095059 PMC11704410__F7 The function of Tanshinone in androgenetic alopecia ENSG00000137857 ENSG00000140279 ENSG00000140254 ENSG00000140274 ENSG00000173612 PMC3749718__F7 The putative steps in the redox signaling pathway leading to adaptive activation of transcription factors and upregulation of the expression of cytoprotective proteins following contractile activity in skeletal muscle ENSG00000284774 ENSG00000105227 PMC4946323__F7 Identification of lineariifolianoid A as a novel dual NFAT1 and MDM2 inhibitor for human cancer therapy ENSG00000175054 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC8139422__F7 SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation ENSG00000115415 ENSG00000130234 ENSG00000288512 ENSG00000173039 ENSG00000117335 ENSG00000182326 PMC7249691__F8 Schematic diagram illustrating the different in canonical versus non-canonical response to IL-12 ENSG00000096996 ENSG00000138378 ENSG00000105397 PMC11281156__F6 Proposed cellular signal transduction pathway of TCBPA-induced cell inflammation in Jurkat cells ENSG00000115008 ENSG00000069956 ENSG00000112115 PMC2675004__F1 Crosstalk via the NFKB Signaling System ENSG00000226275 ENSG00000111321 ENSG00000026103 PMC10975890__F1 MAPK signaling pathway (KEGG: 04010) enriched in bovine fibroblasts infected with B ENSG00000087095 ENSG00000170458 ENSG00000102871 ENSG00000130522 ENSG00000138798 ENSG00000175104 ENSG00000127191 ENSG00000081189 ENSG00000196712 PMC11917101__F11 Inhibition of neutrophil extracellular traps alleviates blood–brain barrier disruption and cognitive dysfunction via Wnt3/Beta-catenin/TCF4 signaling in sepsis-associated encephalopathy ENSG00000168036 ENSG00000005381 ENSG00000277641 ENSG00000196628 PMC3254631__F5 MiRNA Expression by Dietary Polyphenols in apoE Deficient Mice: A New Mechanism of the Action of Polyphenols ENSG00000170458 ENSG00000134982 ENSG00000138798 ENSG00000102302 ENSG00000089159 ENSG00000186469 PMC5240216__F3 IRE1ɑ-XBP1 is one of the arms of UPR that polarizes tumor-infiltrating myeloid cells into highly immunosuppressive populations ENSG00000100219 ENSG00000168610 PMC9632420__F7 Knockdown of USP8 inhibits prostate cancer cell growth, proliferation, and metastasis and promotes docetaxel’s activity by suppressing the NF-kB signaling pathway ENSG00000170558 ENSG00000146648 PMC8899708__F5 New Druggable Targets for Rheumatoid Arthritis Based on Insights From Synovial Biology ENSG00000149968 PMC8150754__F2 Therapeutic Strategies for Metastatic Triple-Negative Breast Cancers: From Negative to Positive ENSG00000134982 ENSG00000163599 ENSG00000198793 ENSG00000136997 PMC3690345__F2 Metabolic crossroads of iron and copper ENSG00000182511 ENSG00000173992 ENSG00000106327 ENSG00000138495 ENSG00000123191 ENSG00000177556 ENSG00000115107 PMC10241773__F2 Epigenetic regulation and therapeutic targets in the tumor microenvironment ENSG00000094631 ENSG00000179934 ENSG00000143546 ENSG00000101574 ENSG00000169245 ENSG00000108691 ENSG00000162402 ENSG00000149658 ENSG00000138755 ENSG00000126353 ENSG00000118520 ENSG00000163517 ENSG00000165819 PMC8379496__AF1 Cell cycle induction in human cardiomyocytes is dependent on biosynthetic pathway activation ENSG00000134057 ENSG00000135446 PMC8466180__F2 Evolving Role of Ferroptosis in Breast Cancer: Translational Implications Present and Future ENSG00000168003 ENSG00000092445 ENSG00000151012 ENSG00000167468 ENSG00000197429 ENSG00000113161 ENSG00000168610 ENSG00000102967 PMC10383069__F2 Understanding the Roles of Very-Long-Chain Polyunsaturated Fatty Acids (VLC-PUFAs) in Eye Health ENSG00000118402 ENSG00000119915 ENSG00000066322 ENSG00000197977 PMC3159521__F2 Pre-B-cell-receptor signaling is regulated by a feed-back loop via Ikaros and Aiolos ENSG00000122025 ENSG00000186716 PMC5504126__F2 Cholesterol synthesis and metabolism in astrocytes and neurons ENSG00000130164 ENSG00000036530 PMC7578258__F2 Metabolic rewiring and redox adaptation induced by BRAFi during melanoma progression ENSG00000157764 PMC7033114__F8 IDO1 and TDO contributing to the malignancy of gliomas ENSG00000106546 ENSG00000171885 PMC9339493__F6 Molecular mechanism, regulation, and therapeutic targeting of the STAT3 signaling pathway in esophageal cancer (Review) ENSG00000291971 ENSG00000168036 ENSG00000168610 PMC9339493__F2 Molecular mechanism, regulation, and therapeutic targeting of the STAT3 signaling pathway in esophageal cancer (Review) ENSG00000134982 ENSG00000168036 ENSG00000168610 ENSG00000125084 PMC2817017__F2 RAS-RAF-MEK-ERK signaling pathway ENSG00000033327 PMC8537916__F2 Mitochondrial Contributions to Hematopoietic Stem Cell Aging ENSG00000162711 ENSG00000187531 ENSG00000125538 ENSG00000198793 ENSG00000015285 ENSG00000142082 PMC7691524__F7 RA Metabolic pathways affected by DEAB and TTNPB treatments ENSG00000095596 ENSG00000138207 ENSG00000003137 ENSG00000121039 ENSG00000128918 ENSG00000162496 ENSG00000292155 ENSG00000138356 PMC9339493__F4 Molecular mechanism, regulation, and therapeutic targeting of the STAT3 signaling pathway in esophageal cancer (Review) ENSG00000040933 ENSG00000122565 ENSG00000168610 PMC4133096__F2 Role of 53BP1 during the cell cycle ENSG00000149311 ENSG00000012048 ENSG00000080345 PMC9339493__F5 Molecular mechanism, regulation, and therapeutic targeting of the STAT3 signaling pathway in esophageal cancer (Review) ENSG00000168610 PMC6421044__F3 Regulatory loop among Kaiso, Wnt11/5a and Suz12 ENSG00000178691 PMC2905064__F2 Integration of oncogenic and tumor suppressor inputs by the GLI code in cancer ENSG00000177606 ENSG00000143839 ENSG00000133961 PMC5648021__F2 Metabolic Instruction of Immunity ENSG00000198793 PMC8666286__F9 CoCrMo‐Nanoparticles induced peri‐implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2‐ARE signalling pathway ENSG00000168003 ENSG00000151012 ENSG00000167468 PMC9433910__F3 Progress in preclinical studies of macrophage autophagy in the regulation of ALI/ARDS ENSG00000162711 ENSG00000198793 PMC2848014__F8 Proteomics Reveals Novel Oxidative and Glycolytic Mechanisms in Type 1 Diabetic Patients' Skin Which Are Normalized by Kidney-Pancreas Transplantation ENSG00000171540 PMC6639367__F1 Cellular glycolysis and oxidative phosphorylation ENSG00000180210 PMC7669588__F2 Pathway for Nucleotide Excision Repair (NER) ENSG00000132646 ENSG00000136936 PMC7186465__F1 Anticipated mechanism of action of IL-17B in tumorigenesis ENSG00000160182 ENSG00000175104 PMC4535882__F7 Multiple Protein Kinases via Activation of Transcription Factors NFKB, AP-1 and C/EBPD Regulate the IL-6/IL-8 Production by HIV-1 Vpr in Astrocytes ENSG00000117020 PMC8353216__F2 COVID-19 pandemic: insights into molecular mechanisms leading to sex-based differences in patient outcomes ENSG00000130234 ENSG00000184012 PMC3932224__F3 Summary of regulatory networks centered by typical 2-Cys Prxs ENSG00000142192 ENSG00000167207 ENSG00000082175 ENSG00000136997 ENSG00000123374 ENSG00000174429 ENSG00000010671 PMC10523190__F1 Progress in the research of cuproptosis and possible targets for cancer therapy ENSG00000188786 ENSG00000123191 ENSG00000137714 ENSG00000131828 ENSG00000091140 PMC11852824__F10 Combinational Inhibition of MEK and AKT Synergistically Induces Melanoma Stem Cell Apoptosis and Blocks NRAS Tumor Growth ENSG00000002330 ENSG00000157764 PMC8080560__F2 Depiction of key proteins targeted by CRLs during cell cycle progression ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC7801270__F1 Melatonin signaling pathway in the occurrence and development of OA ENSG00000150782 ENSG00000105835 ENSG00000102908 ENSG00000096717 PMC8082653__F4 N6-methyladenosine-dependent signalling in cancer progression and insights into cancer therapies ENSG00000145388 ENSG00000174013 ENSG00000198492 ENSG00000124766 ENSG00000107902 ENSG00000091542 ENSG00000196470 ENSG00000099957 ENSG00000167034 ENSG00000107581 ENSG00000101882 ENSG00000149658 ENSG00000040199 ENSG00000128191 ENSG00000165819 ENSG00000113360 PMC4880841__F1 Summary of NDR/LATS kinase signalling functioning downstream of Ste20-like kinases and upstream of the Hippo effectors YAP/TAZ ENSG00000115977 ENSG00000150457 ENSG00000131023 PMC8082653__F3 N6-methyladenosine-dependent signalling in cancer progression and insights into cancer therapies ENSG00000008952 ENSG00000198492 ENSG00000073792 ENSG00000127191 ENSG00000165819 ENSG00000104081 PMC7955048__F5 Direct catalytic asymmetric synthesis of Alpha-chiral bicyclo[1.1.1]pentanes ENSG00000169291 ENSG00000173599 PMC4933865__F6 Multiple modes of action of Mg2+ in attenuating Pi-induced VC in HAVSMC ENSG00000170365 ENSG00000092439 ENSG00000111341 ENSG00000168036 ENSG00000036828 PMC12037972__F1 Overview of serine-glycine-one-carbon (SGOC) metabolic pathway ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC11456611__F7 Colorectal cancer: therapeutic targeting of oncogenic signaling cascades PMC5354739__F1 Pharmacogenetic analysis of high-dose methotrexate treatment in children with osteosarcoma ENSG00000228716 ENSG00000173638 ENSG00000136877 ENSG00000103222 ENSG00000124574 ENSG00000137563 ENSG00000118777 ENSG00000023839 PMC2688935__F3 Networks used to generate simulated data ENSG00000002330 ENSG00000109321 ENSG00000109534 ENSG00000129946 ENSG00000138798 ENSG00000198793 ENSG00000136997 ENSG00000115904 ENSG00000142273 ENSG00000124181 ENSG00000169752 PMC7926039__F2 Fibroblasts involved in the EPAC pathway and connection with fibrosis ENSG00000163914 PMC10603966__F5 Schematic view showing melatonin-mediated actions in stroke ENSG00000162711 ENSG00000136869 ENSG00000005381 ENSG00000096717 ENSG00000142082 ENSG00000127191 ENSG00000168610 ENSG00000079999 PMC8561765__F7 Tea polyphenols alleviate hydrogen peroxide-induced oxidative stress damage through the Mst/Nrf2 axis and the Keap1/Nrf2/HO-1 pathway in murine RAW264.7 cells ENSG00000178573 ENSG00000079999 PMC11456611__F2 The diverse signaling cascades implicated in colorectal carcinogenesis ENSG00000002330 ENSG00000134982 ENSG00000198793 ENSG00000169710 ENSG00000168036 ENSG00000150457 ENSG00000168040 ENSG00000131023 ENSG00000164305 ENSG00000149311 ENSG00000136997 ENSG00000128602 ENSG00000178568 PMC3466514__F1 S6K1 in ER-positive breast cancer ENSG00000163235 ENSG00000138798 ENSG00000169047 ENSG00000146648 ENSG00000140443 PMC1667087__F9 F igure 9.— ENSG00000069869 ENSG00000065526 ENSG00000146648 PMC6891198__F7 ALK and RET inhibitors promote HLA class I antigen presentation and unmask new antigens within the tumor immunopeptidome ENSG00000115415 PMC4002321__F2 PI3K/Akt pathway involved in tumorigenesis ENSG00000002330 PMC10818876__F2 Signaling pathways triggered by traditional medicine-derived SCFAs ENSG00000278718 ENSG00000162711 ENSG00000198793 ENSG00000172936 ENSG00000168610 ENSG00000106546 PMC6696851__F8 Schematic diagram depicting possible mechanisms involved in the anti-fibrotic effect of melatonin and PAA ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000125084 PMC4592520__F1 MicroRNAs in placental health and disease ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC3048826__F9 Hsp72 is an important intracellular protein to inhibition of HMGB1 release and proinflammatory function in macrophages () ENSG00000189403 PMC5352135__F8 miR-103 inhibits proliferation and sensitizes hemopoietic tumor cells for glucocorticoid-induced apoptosis ENSG00000107404 ENSG00000145321 ENSG00000168036 ENSG00000123374 PMC2842492__F2 Transcripts regulating the mammalian cell cycle are up-regulated in the proliferative-phase endometrial epithelium ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000134982 ENSG00000135446 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000105810 ENSG00000117399 ENSG00000276876 PMC6429142__F8 Tangeretin-induced apoptotic pathway in BFTC-905 bladder cancer cells ENSG00000002330 ENSG00000171791 PMC4300205__F1 Human Cerberus Prevents Nodal-Receptor Binding, Inhibits Nodal Signaling, and Suppresses Nodal-Mediated Phenotypes ENSG00000156574 PMC6026692__F2 Dual Effect of Hepatic Macrophages on Liver Ischemia and Reperfusion Injury during Liver Transplantation ENSG00000239732 ENSG00000116688 ENSG00000125538 ENSG00000189403 ENSG00000136869 ENSG00000162692 PMC3048826__F8 Hsp72 regulates oxidative stress-induced HMGB1 cytoplasmic translocation and release ENSG00000005893 ENSG00000189403 PMC4786758__F3 Position of miRNA targeted genes (red box) in endometrial carcinogenesis pathway (KEGG) ENSG00000117020 ENSG00000002330 ENSG00000134982 ENSG00000115904 ENSG00000121879 ENSG00000168646 ENSG00000146648 PMC9699401__F11 Ginsenoside Rh2 Induces HeLa Apoptosis through Upregulating Endoplasmic Reticulum Stress-Related and Downstream Apoptotic Gene Expression ENSG00000105327 ENSG00000128272 PMC3481527__F3 CB1 cannabinoid receptor signalling and regulation of neural stem/progenitor cell proliferation ENSG00000076864 ENSG00000291971 ENSG00000168610 PMC4452102__F1 TLRs in human gastrointestinal pathology: health condition and inflammation ENSG00000111537 PMC5069789__F2 Epigenetic mechanisms mediate DEP effects on asthma pathogenesis ENSG00000150782 ENSG00000148400 ENSG00000163235 ENSG00000145777 ENSG00000140465 ENSG00000146648 ENSG00000115009 ENSG00000106546 PMC2974067__F1 Signaling pathways that regulate longevity in C ENSG00000129347 ENSG00000118515 PMC7400296__F1 Fibrosis regulation by RBM7 via NEAT1 ncRNA decay in the lung ENSG00000107562 ENSG00000076053 PMC7016888__F4 Cell signaling determination of artery, vein and lymph identity ENSG00000196411 ENSG00000135547 ENSG00000117707 ENSG00000203883 PMC4873349__F2 IPA canonical pathway Cell Cycle: G1/S Checkpoint Regulation with up-regulated genes in the IR-induced common translatome highlighted in pink ENSG00000149311 ENSG00000175054 ENSG00000168283 ENSG00000101945 ENSG00000123374 ENSG00000169375 PMC10299070__F3 Core pathways involved in development of Peyronie’s disease and their interrelationships ENSG00000164690 ENSG00000104332 ENSG00000128602 PMC7583981__F1 Pyroptosis canonical pathway and non-canonical pathway ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000091106 PMC7583981__F2 Oxidative stress and ER stress in inflammation in DKD ENSG00000162711 ENSG00000125538 ENSG00000086991 ENSG00000265972 PMC12249569__F1 Mechanistic model linking gut dysbiosis, insulin resistance, and autism spectrum disorder ENSG00000174125 ENSG00000169047 ENSG00000172936 ENSG00000175104 PMC7859757__F4 ER stress can be triggered by alcohol, bile acids, pancreatic toxins, and increased protein synthesis ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC7551201__F2 RAGE signaling pathway ENSG00000148346 ENSG00000087245 ENSG00000115008 ENSG00000070831 ENSG00000138798 ENSG00000163874 ENSG00000198793 ENSG00000196154 ENSG00000168036 ENSG00000171791 ENSG00000136960 ENSG00000125398 ENSG00000108688 ENSG00000136869 ENSG00000118520 ENSG00000172936 ENSG00000185591 ENSG00000100985 ENSG00000096717 PMC12040832__F1 Underlying protective mechanism of EOs against oxidative damage induced by chemical overexposure ENSG00000198793 ENSG00000130649 ENSG00000173599 ENSG00000171791 ENSG00000005381 ENSG00000079999 PMC5766484__F4 Expression of key biological pathways involved in M ENSG00000134042 ENSG00000167074 ENSG00000167419 PMC2666018__F12 Differential Requirement for MEK/ERK and SMAD Signaling in PAI-1 and CTGF Expression in Response to Microtubule Disruption ENSG00000291971 ENSG00000146648 PMC7115204__F2 Signaling pathway of G-CSF in breast cancer ENSG00000087245 ENSG00000163235 ENSG00000198793 ENSG00000135097 PMC5570234__F2 MinePath viewer for BM20 region normal versus high Alzheimer's disease based on the CERAD classification ENSG00000070831 ENSG00000134215 ENSG00000115904 ENSG00000124126 ENSG00000158517 ENSG00000169032 ENSG00000089159 ENSG00000148498 ENSG00000129946 ENSG00000149269 ENSG00000166501 ENSG00000113263 ENSG00000100906 ENSG00000109320 ENSG00000127955 ENSG00000213341 ENSG00000067900 ENSG00000182621 ENSG00000164742 ENSG00000117020 ENSG00000120899 ENSG00000115415 ENSG00000067606 ENSG00000015285 ENSG00000105723 ENSG00000069966 PMC6468358__F1 ADRB2 signaling in prostate cancer ENSG00000002330 PMC11941040__F3 Acute inflammation and molecular pathways induced by red complex bacteria and Fusobacterium nucleatum in endothelial cells ENSG00000174125 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000162692 ENSG00000254550 PMC9406806__F8 Nano Modification of Antrodia Cinnamomea Exhibits Anti-Inflammatory Action and Improves the Migratory Potential of Myogenic Progenitors ENSG00000170558 ENSG00000174804 ENSG00000168036 ENSG00000108654 ENSG00000196628 PMC7214760__F1 Biosynthetic pathway of aromatic amino acids ENSG00000197487 ENSG00000116984 PMC8436866__F2 Research Progress on Mechanism of Neuroprotective Roles of Apelin-13 in Prevention and Treatment of Alzheimer’s Disease ENSG00000162711 ENSG00000128272 ENSG00000198793 ENSG00000265972 ENSG00000100219 PMC7583981__F5 Pyroptosis contributes to interstitial fibrosis ENSG00000162711 ENSG00000150782 PMC5206730__F6 Effects of Lactobacillus plantarum on small intestinal barrier function and mucosal gene transcription; a randomized double-blind placebo controlled trial ENSG00000019991 ENSG00000070831 ENSG00000170458 ENSG00000291971 ENSG00000109113 ENSG00000149269 ENSG00000138798 ENSG00000165527 PMC7551201__F5 S100A8/A9 provides a premetastatic environment ENSG00000148346 ENSG00000143546 ENSG00000136960 ENSG00000163220 ENSG00000163739 ENSG00000163874 ENSG00000108688 ENSG00000136869 ENSG00000118520 PMC7414267__F2 Pro-viral and antiviral roles of TRIM6 ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000121236 ENSG00000121060 ENSG00000118640 ENSG00000142166 PMC7551201__F6 S100A4 increased motility of tumor cells ENSG00000196154 ENSG00000168036 ENSG00000136869 PMC5206730__F7 Effects of Lactobacillus plantarum on small intestinal barrier function and mucosal gene transcription; a randomized double-blind placebo controlled trial ENSG00000169291 ENSG00000099942 PMC7816137__F3 Met1-linked ubiquitin machinery in inflammation and infection ENSG00000183735 ENSG00000083799 ENSG00000154124 PMC7816137__F4 Met1-linked ubiquitin machinery in inflammation and infection ENSG00000088888 ENSG00000083799 ENSG00000154124 ENSG00000185651 PMC3231924__F1 Simplified scheme for TLR signaling in enterocytes ENSG00000174125 ENSG00000239732 ENSG00000167207 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000106100 ENSG00000164342 PMC5197954__F1 Intronic microRNAs (miRNAs) and the miRNA-488/ZIP8/MTF1 pathway are critically involved in the pathogenesis of osteoarthritis (OA) ENSG00000188786 PMC8827164__F5 Transcriptional landscape of circulating platelets from patients with COVID-19 reveals key subnetworks and regulators underlying SARS-CoV-2 infection: implications for immunothrombosis ENSG00000291931 ENSG00000259207 ENSG00000198755 ENSG00000005961 ENSG00000110799 ENSG00000164587 ENSG00000213741 ENSG00000124491 ENSG00000147604 ENSG00000161016 ENSG00000166501 ENSG00000197943 ENSG00000171608 PMC10480466__F7 Lenvatinib inhibition of EMT in ICC cells ENSG00000170558 PMC5724804__F5 SIRT6 histone deacetylase functions as a potential oncogene in human melanoma ENSG00000261832 ENSG00000152348 ENSG00000163131 ENSG00000144848 ENSG00000284099 ENSG00000141458 ENSG00000145782 PMC8960222__F2 Rewiring mitochondrial metabolism to counteract exhaustion of CAR-T cells ENSG00000136997 ENSG00000198846 ENSG00000106459 PMC6374178__F4 Possible neurochemical/molecular pathways for stress-induced synaptic remodeling in medial prefrontal cortex ENSG00000198793 ENSG00000145321 PMC11887407__F4 Oncogenic GNAS activation and downstream signal transduction ENSG00000142178 ENSG00000160584 ENSG00000089685 ENSG00000291971 ENSG00000134982 ENSG00000136997 ENSG00000170145 ENSG00000168036 ENSG00000164690 ENSG00000128602 ENSG00000168610 ENSG00000131023 PMC10526836__F1 Interleukin-21 Influences Glioblastoma Course: Biological Mechanisms and Therapeutic Potential ENSG00000111837 ENSG00000103522 ENSG00000105639 ENSG00000168610 PMC11587777__F1 Immunopathological interactions in tuberculosis-associated hemophagocytic lymphohistiocytosis (TB-HLH) ENSG00000134982 ENSG00000138755 PMC5345529__F1 Interaction of VHL protein with HIF and other proteins including elongin B, elongin C and CUL2 ENSG00000134086 ENSG00000163235 PMC3490581__F4 Illustration of fluxes in central carbon metabolism for metabolic phases II and III along the protein/ tradeoff ENSG00000172005 ENSG00000135678 PMC5344275__F4 Biological responses leading to angiogenesis driven by the HGF–Met pathway ENSG00000019991 ENSG00000168610 PMC4590678__F1 Genes involved in Parkinson disease and in the autophagy-lysosome pathway ENSG00000100225 ENSG00000078081 ENSG00000158828 ENSG00000069329 ENSG00000112561 ENSG00000127419 ENSG00000165280 ENSG00000182220 ENSG00000291761 ENSG00000136235 ENSG00000138760 PMC7465660__F5 Relationship between EBV proteins, hTERT, and NOTCH signaling pathway and the modes of action of compounds with lytic induction potentials ENSG00000169554 ENSG00000156127 ENSG00000095002 PMC5344275__F2 Signaling mechanisms responsible for promotion of cell survival mediated by HGF–Met pathway ENSG00000019991 ENSG00000002330 ENSG00000026103 PMC5344275__F1 Schematic structures of HGF (A) and Met (B) ENSG00000168610 PMC8298384__F9 Anti-diabetic effects of NAG-1/GDF15 on HFD/STZ-induced mice ENSG00000150907 ENSG00000169047 ENSG00000196396 PMC7933474__F1 Schematic diagram depicting a proposal model of the complex relationship between autophagy and exosomes in the context of pancreas ductal adenocarcinoma (PDAC) and its environment ENSG00000164938 ENSG00000100985 ENSG00000168615 PMC3491835__F7 5-HT6 receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia ENSG00000198793 PMC5476461__F4 Regulation of antioxidant production by HIF-1 ENSG00000065911 ENSG00000151012 ENSG00000092621 ENSG00000135069 ENSG00000146733 ENSG00000023909 ENSG00000120254 PMC6406290__F6 Network analysis of differentially expressed genes ENSG00000109756 ENSG00000184205 PMC12065456__F3 Communication between cancer-associated fibroblasts and specific tumor cells via integrins ENSG00000135218 ENSG00000186340 ENSG00000170558 ENSG00000145321 ENSG00000121966 PMC8753223__F7 Inducible Sbds deletion impairs bone marrow niche capacity to engraft donor bone marrow after transplantation ENSG00000178860 ENSG00000107562 ENSG00000157601 PMC12065456__F4 Summary diagram of the interplay between integrins and cancer stem cells in specific tumor types ENSG00000187605 ENSG00000133937 ENSG00000168036 ENSG00000010278 ENSG00000168610 ENSG00000136826 PMC8777512__F1 O-GlcNAcylation links oncogenic signals and cancer epigenetics ENSG00000100522 ENSG00000147162 ENSG00000198380 ENSG00000198408 ENSG00000013375 PMC5515442__F8 Suppressive effect of AMP-activated protein kinase on the epithelial-mesenchymal transition in retinal pigment epithelial cells ENSG00000197713 ENSG00000198793 PMC12235270__F2 Unraveling the Hippo pathway: YAP/TAZ as central players in cancer metastasis and drug resistance ENSG00000150457 ENSG00000131023 PMC12065456__F2 Pro- and anti-tumorigenic effects of integrins on interaction between endothelial cells and particular tumor cells ENSG00000135218 ENSG00000070831 ENSG00000173269 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000163914 ENSG00000125810 ENSG00000162692 ENSG00000127191 PMC7226356__F1 Perforin-granzyme, intrinsic (mitochondrial) and extrinsic apoptotic pathway PMC11750448__F4 Network view depicting hub metabolites, their associated miRNAs, and the target genes within the corresponding metabolic pathway ENSG00000138115 ENSG00000276559 ENSG00000144644 ENSG00000130649 PMC11960544__F3 Exploration of the signaling pathway of extracellular matrix (ECM)-receptor interaction in stem cells from human exfoliated deciduous teeth-conditioned medium (SHED-CM) ENSG00000136457 ENSG00000135218 ENSG00000168743 ENSG00000110799 ENSG00000026508 ENSG00000152592 PMC8547806__F2 Necrotizing Enterocolitis: LPS/TLR4-Induced Crosstalk Between Canonical TGFB/Wnt/Beta-Catenin Pathways and PPARG ENSG00000134982 ENSG00000138798 ENSG00000168036 ENSG00000198125 PMC8547806__F3 Necrotizing Enterocolitis: LPS/TLR4-Induced Crosstalk Between Canonical TGFB/Wnt/Beta-Catenin Pathways and PPARG ENSG00000134982 ENSG00000168036 ENSG00000136869 PMC7728579__F2 Transsulfuration and H2S oxidation pathways ENSG00000139531 ENSG00000166278 PMC8539471__F3 Controversial Role of Adiponectin in Appetite Regulation of Animals ENSG00000198576 ENSG00000115138 ENSG00000159346 PMC5578419__F2 Experimental models of hepatitis B and C — new insights and progress ENSG00000015520 ENSG00000110651 PMC3163776__F3 IRE1Alpha-XBP1 pathway in glucose homeostasis ENSG00000132478 ENSG00000127191 PMC3163776__F2 IRE1Alpha-XBP1 pathway in inflammation ENSG00000172239 ENSG00000136869 ENSG00000175104 ENSG00000127191 PMC4273448__F7 The structure-function relationships of IRAK-M based on this study ENSG00000172936 ENSG00000175104 PMC4817806__F8 Proposed mechanism by which DZNep epigenetically reactivates Wnt/Beta-catenin signaling to promote osteogenic differentiation of osteoporosis BMSCs ENSG00000125084 PMC5423221__F5 Metastatic niches in the bone marrow ENSG00000107562 ENSG00000291971 ENSG00000170558 ENSG00000198793 ENSG00000121966 PMC4620719__F2 Cross-regulation of intracellular membrane-associated proteins and microRNAs in B cell differentiation ENSG00000145782 ENSG00000057663 PMC9687179__F1 Multi-Layered Regulations on the Chromatin Architectures: Establishing the Tight and Specific Responses of Fission Yeast fbp1 Gene Transcription ENSG00000123268 PMC6651255__F2 STNM01 blocks the glycosaminoglycan synthesis pathway through RNA-induced silencing complex (RISC) activation ENSG00000069482 ENSG00000062485 PMC4364402__F2 Models of peripheral and spinal itch circuitry ENSG00000078747 PMC6059739__F3 Regulation of the Wnt pathway via YAP/TAZ ENSG00000004975 ENSG00000168036 ENSG00000196628 PMC4445092__F2 Schematic presentation of testosterone-activated extra-nuclear signaling pathways ENSG00000291971 ENSG00000129214 ENSG00000146648 PMC6451008__F1 PTEN S-nitrosylation by NOS1 inhibits autophagy in NPC cells ENSG00000198793 PMC7967197__F1 CyclinD/CDK4/6 involvement in overpassing resistance to aromatase inhibitors ENSG00000135446 ENSG00000198793 ENSG00000146648 PMC9021737__F5 De Novo Assembly of 20 Chicken Genomes Reveals the Undetectable Phenomenon for Thousands of Core Genes on Microchromosomes and Subtelomeric Regions ENSG00000104856 ENSG00000167601 ENSG00000105298 ENSG00000088247 ENSG00000120885 ENSG00000265972 ENSG00000131323 ENSG00000105568 ENSG00000136695 ENSG00000127191 ENSG00000086758 ENSG00000010671 PMC4658488__F1 Cholesterol biosynthetic pathway and cholesterol synthesis inhibitors used in the current study ENSG00000067064 ENSG00000110921 ENSG00000116133 ENSG00000172893 ENSG00000167941 ENSG00000109929 ENSG00000197429 ENSG00000113161 ENSG00000148377 PMC5859872__F2 Cooperative interactions between the tumour and surrounding cells in tumorigenesis ENSG00000087245 ENSG00000146648 PMC5859872__F3 Non-cell-autonomous overgrowth ENSG00000131475 ENSG00000074319 PMC3124126__F1 Molecular signaling cascades which normally control mTORC1 activity and may become dysregulated in B-cell lymphomas leading to aberrant mTORC1 signaling activation PMC5859872__F1 Cell competition mechanisms ENSG00000185008 PMC6421314__F1 Relationship between Fe deficiency responses in dicots and responses to pathogens (necrotrophs or biotrophs that elicit SAR) or to beneficial microbes that elicit ISR ENSG00000105664 PMC4313785__F1 Figitumumab (CP) is a biased agonist of the IGF1R that selectively promotes Beta-arrestin1 (Beta-arr1) signaling in cancer cells ENSG00000169047 PMC3928074__F1 Phase II Trials of Single Agent Anti-VEGF Therapy for Patients with Chronic Lymphocytic Leukemia (CLL) ENSG00000168610 PMC3307977__F6 Schematic diagram of the FGF2-STAT3-PAX3 signaling pathway ENSG00000135903 ENSG00000168610 PMC5430039__F4 Host miRNAs that favor viral replication via the inhibition of the Jak/STAT signaling pathway ENSG00000213928 PMC11889548__F5 Abnormal Hedgehog (Hh) signal transduction caused by EFCAB7 mutation ENSG00000159224 ENSG00000173040 ENSG00000183072 ENSG00000203965 ENSG00000197616 ENSG00000128602 PMC7865717__F3 RSV could prevent oxidative stress involved in the development and progression of ocular diseases such as age-related macular degeneration (AMD) ENSG00000197713 ENSG00000112715 ENSG00000111816 PMC7865717__F4 Proposed model of resveratrol action during oxidative stress in glaucoma ENSG00000197713 ENSG00000096717 PMC8040975__F3 TSP1 and ligands in glucose metabolism and diabetes mellitus ENSG00000135218 ENSG00000198053 ENSG00000105329 ENSG00000175567 PMC8040975__F4 TSP1 in adipose metabolism and obesity ENSG00000135218 ENSG00000105329 ENSG00000168610 PMC5843355__F1 Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery ENSG00000137198 ENSG00000198931 ENSG00000119125 PMC8804234__F3 Molecular Mechanisms of Clonorchis sinensis-Host Interactions and Implications for Vaccine Development ENSG00000095739 ENSG00000137033 ENSG00000172936 ENSG00000136869 PMC4190578__F5 Metabolic pathways for carbohydrates, fatty acids and phenylalanine ENSG00000109814 ENSG00000111816 ENSG00000084774 PMC3154472__F1 Identification and Phylogenetic Analysis of Heme Synthesis Genes in Trypanosomatids and Their Bacterial Endosymbionts ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000188690 PMC6477175__F1 Distribution of target proteins of baicalin in the “Alzheimer’s disease pathway” ENSG00000142192 ENSG00000182511 ENSG00000002330 ENSG00000168040 ENSG00000119912 ENSG00000164305 PMC7370155__F1 HMGB1 mediated neuroinflammatory response in TBI ENSG00000125538 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC3076058__F2 Recent insights into cerebral cavernous malformations: a complex jigsaw puzzle under construction ENSG00000070831 ENSG00000198742 PMC6477175__F2 Distribution of target proteins of icariin within the “Alzheimer’s disease pathway” ENSG00000142192 ENSG00000182511 ENSG00000002330 ENSG00000168040 ENSG00000119912 ENSG00000164305 PMC7370155__F2 HMGB1-mediated EBI post-SAH ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000168610 PMC9605147__F1 Let-7 microRNAs Are Possibly Associated with Perineural Invasion in Colorectal Cancer by Targeting IGF Axis ENSG00000171105 ENSG00000197081 ENSG00000169047 PMC6395431__F1 Biochemical pathway ENSG00000059573 ENSG00000118520 ENSG00000036473 PMC4693271__F1 Toll-like receptors (TLR) 4-mediated signaling of innate immune responses ENSG00000104856 ENSG00000172005 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000175104 PMC6126897__F2 Functions of iTreg in the TME ENSG00000198793 ENSG00000049768 PMC4693271__F4 Ubiquitination-mediated signaling cascades in canonical and non-canonical NFKB pathways ENSG00000104856 ENSG00000102871 ENSG00000157625 ENSG00000131323 ENSG00000127191 PMC4989114__F1 Coelimination and Survival in Gene Network Evolution: Dismantling the RA-Signaling in a Chordate ENSG00000121039 ENSG00000118514 ENSG00000135697 PMC6477175__F3 Distribution of target proteins of dihydromyricetin within the “Alzheimer’s disease pathway” ENSG00000142192 ENSG00000182511 ENSG00000002330 ENSG00000168040 ENSG00000119912 ENSG00000164305 PMC6477175__F4 Distribution of target proteins of hesperidin in the “Alzheimer’s disease pathway” ENSG00000142192 ENSG00000182511 ENSG00000002330 ENSG00000168040 ENSG00000119912 ENSG00000164305 PMC11842335__F3 Activating the Nrf2/KEAP1 signaling pathway to counteract oxidative stress and subsequent inflammatory reactions, including mastitis, induced by LPS through the administration of bioactive compounds from an external source ENSG00000079999 PMC11842335__F2 Underlined molecular mechanism during mastitis development ENSG00000079999 PMC7887651__F4 Immunometabolic interplay in obesity ENSG00000169047 ENSG00000168610 PMC6909602__F6 Schematic of the mechanism by which Alpha-synuclein induces the accumulation of microglia through CXCL12/CXCR4 ENSG00000107562 ENSG00000109320 ENSG00000291971 ENSG00000136869 ENSG00000121966 PMC3449280__F1 An engineered eukaryotic protein glycosylation pathway in Escherichia coli ENSG00000101901 ENSG00000146416 ENSG00000033011 PMC10825793__F3 EBV-miRNAs modulating inflammatory signaling pathways ENSG00000088888 ENSG00000102871 ENSG00000010810 ENSG00000177606 ENSG00000213341 ENSG00000160293 ENSG00000105639 ENSG00000276561 PMC8435254__F2 Serum L‐arginine and endogenous methylarginine concentrations predict irritable bowel syndrome in adults: A nested case‐control study ENSG00000146469 ENSG00000139549 PMC4957398__F2 Signaling of pexophagy by ROS, hypoxia and inhibition of PEX5 export from peroxisomes ENSG00000149311 ENSG00000177169 ENSG00000188554 ENSG00000150991 ENSG00000288217 PMC3228119__F1 PI3K/AKT/mTOR signaling network regulates cell survival, proliferation, migration, metabolism, and apoptosis, integrating the growth factor signaling pathway, nutrient status, and other oncogenic pathways ENSG00000002330 ENSG00000169047 ENSG00000198793 ENSG00000284161 ENSG00000164327 PMC8874739__F6 PACAP-38 Induces Transcriptomic Changes in Rat Trigeminal Ganglion Cells Related to Neuroinflammation and Altered Mitochondrial Function Presumably via PAC1/VPAC2 Receptor-Independent Mechanism ENSG00000124102 ENSG00000130528 ENSG00000118729 ENSG00000181104 ENSG00000143933 ENSG00000101306 ENSG00000198363 ENSG00000109689 ENSG00000123360 ENSG00000176884 ENSG00000138193 ENSG00000148660 ENSG00000065526 ENSG00000186716 ENSG00000083444 ENSG00000196218 ENSG00000124181 ENSG00000077782 PMC4677817__F2 Contribution of Metabolic Reprogramming to Macrophage Plasticity and Function ENSG00000118520 PMC4383156__F5 The major pathways involved in the molecular mechanisms of cancer ENSG00000070831 ENSG00000168040 PMC1905066__F5 CRP and mannan-binding lectin (MBL) on complement activation ENSG00000113600 ENSG00000288512 ENSG00000166278 ENSG00000082212 ENSG00000132693 ENSG00000182326 PMC6117622__F4 MAPK signaling pathway ENSG00000087095 ENSG00000163930 ENSG00000170458 ENSG00000138798 ENSG00000177606 ENSG00000198517 ENSG00000175104 ENSG00000127191 ENSG00000146648 ENSG00000026103 PMC11373554__F7 MetaCore enrichment pathway analysis of genes coexpressed with KDM5B in pancreatic cancer ENSG00000142192 ENSG00000138380 ENSG00000196591 ENSG00000164362 ENSG00000168036 ENSG00000139372 ENSG00000164690 ENSG00000043039 ENSG00000155974 ENSG00000146648 ENSG00000196628 ENSG00000164916 PMC11373554__F5 MetaCore pathway analysis of the coexpression gene network involving KDM1A in pancreatic cancer ENSG00000149311 ENSG00000175054 ENSG00000070831 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC5957297__F3 MAPK pathway in BRAF-mutant melanoma ENSG00000019991 ENSG00000157764 ENSG00000146648 PMC11373554__F6 Expression of the KDM5A signaling pathway in pancreatic cancer (MetaCore) ENSG00000149311 ENSG00000281766 ENSG00000012048 ENSG00000175054 ENSG00000019991 ENSG00000135446 ENSG00000054796 PMC5957297__F4 MAPK pathway bypass in melanoma ENSG00000157764 PMC5957297__F5 MAPK pathway indifference in melanoma ENSG00000157764 PMC9705963__F1 Ferroptosis in osteosarcoma: A promising future ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000066135 ENSG00000111684 ENSG00000168610 ENSG00000115107 ENSG00000127948 PMC6527835__F1 Schematic illustration of the mammalian ganglioside synthesis pathway ENSG00000172318 ENSG00000135454 ENSG00000213614 ENSG00000196743 ENSG00000158470 ENSG00000049860 ENSG00000115525 ENSG00000148154 PMC4118962__F1 Interleukin-1/Toll-Like Receptor-Induced Nuclear Factor Kappa B Signaling Participates in Intima Hyperplasia after Carotid Artery Balloon Injury in Goto-Kakizaki Rats: A Potential Target Therapy Pathway ENSG00000134070 ENSG00000172936 ENSG00000175104 PMC3439646__F1 Complement and dysbiosis in periodontal disease ENSG00000174125 ENSG00000111537 ENSG00000170458 ENSG00000136869 ENSG00000125347 ENSG00000121966 PMC7213603__F4 Schematic representation for a proposed pathway showing upstream regulation of EZH2 in SLE CD4+ T cells ENSG00000198793 ENSG00000155792 ENSG00000167965 PMC11986939__F3 PPI network vs ENSG00000157404 ENSG00000171105 ENSG00000291971 ENSG00000146648 PMC4154952__F5 Mechanical offloading of incisional wounds is associated with transcriptional downregulation of inflammatory pathways in a large animal model ENSG00000261371 ENSG00000111729 ENSG00000078900 ENSG00000291483 ENSG00000065029 ENSG00000111816 ENSG00000174547 ENSG00000130810 ENSG00000198178 PMC9463134__F1 InterferonG receptor pathway: a new way to regulate CAR T cell-solid tumor cell adhesion ENSG00000111537 PMC4530463__F1 Basic biology and role of interleukin-17 in immunity and inflammation ENSG00000082512 ENSG00000157625 ENSG00000175104 ENSG00000127191 ENSG00000163702 PMC8579641__F1 Regulatory mechanism of neutrophil extracellular traps in cancer biological behavior ENSG00000109861 ENSG00000137275 ENSG00000291971 ENSG00000189403 ENSG00000136869 PMC8579641__F2 Regulatory mechanism of neutrophil extracellular traps in cancer biological behavior ENSG00000239732 ENSG00000189403 ENSG00000136869 ENSG00000100985 ENSG00000168610 PMC9204485__F1 Love-Hate Relationship Between TGFB Signaling and the Immune System During Development and Tumorigenesis ENSG00000140564 ENSG00000198793 ENSG00000163914 ENSG00000175104 PMC6362006__F7 Schematic depicting ghrelin’s proposed effect on contact dermatitis and psoriasis ENSG00000102871 ENSG00000125538 ENSG00000168040 ENSG00000127191 PMC9371342__F1 Summary of the major components of the extrinsic and intrinsic pathways of apoptosis induction following viral infection ENSG00000164430 ENSG00000128272 ENSG00000164342 PMC4370699__F5 Activation of CNTF/CNTFRA Signaling Pathway by hRheb(S16H) Transduction of Dopaminergic Neurons In Vivo ENSG00000242689 PMC5241776__F2 Molecular Characterization of Pediatric Restrictive Cardiomyopathy from Integrative Genomics ENSG00000004975 ENSG00000112576 ENSG00000120500 ENSG00000145681 ENSG00000130522 ENSG00000198793 ENSG00000164327 ENSG00000102178 ENSG00000089159 ENSG00000175895 ENSG00000066044 ENSG00000136997 ENSG00000116030 ENSG00000237834 ENSG00000162552 ENSG00000168028 ENSG00000027075 ENSG00000145708 ENSG00000138795 ENSG00000078668 ENSG00000112562 ENSG00000173039 ENSG00000100083 ENSG00000106483 ENSG00000197616 ENSG00000092330 ENSG00000175334 ENSG00000292120 ENSG00000106617 ENSG00000143768 ENSG00000113296 ENSG00000163794 ENSG00000116584 PMC5086619__F1 Mammalian target of rapamycin complex 1 (mTORC1) pathway and translation initiation ENSG00000198793 ENSG00000155792 PMC2424294__F2 Induction and lifetimes of signal transduction proteins (and their mRNAs) at various positions in signal transduction networks ENSG00000163235 ENSG00000179091 ENSG00000095321 ENSG00000187266 PMC11240421__F13 CK1A interplay in the NFKB pathway ENSG00000065978 ENSG00000137275 ENSG00000102871 ENSG00000082512 ENSG00000173039 ENSG00000172936 ENSG00000157625 ENSG00000083799 ENSG00000154124 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC10755915__F6 Soluble CD83 modulates human-monocyte-derived macrophages toward alternative phenotype, function, and metabolism ENSG00000177575 ENSG00000135218 ENSG00000125144 ENSG00000038945 ENSG00000229314 ENSG00000136826 ENSG00000132170 ENSG00000135929 PMC4584235__F6 MiR-146 a/b effect on induction of endotoxin tolerance ENSG00000020633 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000168610 PMC6614380__F1 Pathways to B cell memory ENSG00000186716 ENSG00000105656 PMC9315518__F8 Identification and Functional Analysis of Individual-Specific Subpathways in Lung Adenocarcinoma ENSG00000126016 ENSG00000134982 ENSG00000081051 ENSG00000116962 PMC5869528__F10 Cytokine-cytokine receptor interaction signaling pathway ENSG00000110944 ENSG00000157404 ENSG00000138798 ENSG00000183625 ENSG00000163083 ENSG00000138071 ENSG00000111321 ENSG00000121807 ENSG00000142224 ENSG00000122025 ENSG00000135960 ENSG00000128052 ENSG00000158825 ENSG00000147896 ENSG00000113520 ENSG00000164400 ENSG00000037280 ENSG00000128342 ENSG00000026103 ENSG00000104899 ENSG00000143185 ENSG00000099985 ENSG00000119535 ENSG00000145777 ENSG00000162594 ENSG00000226275 ENSG00000137077 PMC8467693__F1 Personalised Medicine for Colorectal Cancer Using Mechanism-Based Machine Learning Models ENSG00000154342 ENSG00000136997 ENSG00000168036 PMC5869528__F11 Jak-STAT signaling pathway ENSG00000137193 PMC9171628__F2 Rational Use of Complement Inhibitors in Kidney Diseases ENSG00000009724 ENSG00000236625 PMC12146007__F15 Bioactive components-modified smart implants for vascularization and osteogenesis ENSG00000102158 ENSG00000061273 ENSG00000134871 PMC5869528__F12 NOD-like receptor signaling pathway ENSG00000108691 ENSG00000167207 ENSG00000148798 ENSG00000087077 PMC12179907__F2 Epigenetic modification mechanisms in congenital scoliosis ENSG00000173821 ENSG00000118972 ENSG00000169071 ENSG00000291971 ENSG00000134982 ENSG00000131149 ENSG00000168036 ENSG00000108821 ENSG00000185008 ENSG00000184985 ENSG00000136205 PMC6548783__F3 IL-6 production by blood leukocytes is altered in the RA-like PsoA patient in response to immune activators ENSG00000162711 ENSG00000167207 ENSG00000163568 ENSG00000125538 ENSG00000056972 ENSG00000082512 ENSG00000136869 ENSG00000175104 ENSG00000127191 PMC7016982__F1 Regulation of YAP at the level of the extracellular matrix involves various proteins involved in stabilizing and activating YAP ENSG00000291971 ENSG00000196923 PMC7016982__F2 Pathways and interplay with regulate mechanotransduction in the context of chronic disease and polarity ENSG00000169047 ENSG00000163914 ENSG00000103335 PMC6936658__F5 Significantly down regulated genes (from the current study; PLIN1, SORBS1, FABP4, etc) involved in the PPAR signaling pathway is highlighted in red color ENSG00000100979 PMC7758401__F1 Establishment, maintenance and erasing of 5mC in plants ENSG00000134698 ENSG00000123908 PMC7912637__F6 Mechanistic diagram for microglial IRF5/4 activation ENSG00000137265 ENSG00000113520 ENSG00000172936 ENSG00000136869 ENSG00000118520 ENSG00000175104 PMC11557232__F6 Model for the functions and acquisition pathways of acetyl-CoA in multiple organelles of Toxoplasma ENSG00000122966 ENSG00000134982 ENSG00000172005 PMC8237569__F3 Potency boost of a Mycobacterium tuberculosis dihydrofolate reductase inhibitor by multienzyme F420H2-dependent reduction ENSG00000228716 ENSG00000181418 ENSG00000102302 PMC5226065__F4 Mechanisms underlying SQ induced self-renewal ENSG00000198793 ENSG00000163914 PMC206993__F9 SPARC-mediated regulation of and coupling to the TGFB signaling system ENSG00000113140 ENSG00000123374 PMC9358627__F4 Association of ABCC2 haplotypes to Mycophenolic Acid Pharmacokinetics in Stable Kidney Transplant Recipients ENSG00000172831 ENSG00000106348 ENSG00000138115 ENSG00000178035 ENSG00000171234 ENSG00000023839 PMC6528834__F10 DUAL INHIBITION OF ERK1/2 AND AKT PATHWAYS IS REQUIRED TO SUPPRESS THE GROWTH AND SURVIVAL OF ENDOMETRIOTIC CELLS AND LESIONS ENSG00000002330 ENSG00000171791 ENSG00000164305 PMC8623546__F5 Nephronophthisis-Pathobiology and Molecular Pathogenesis of a Rare Kidney Genetic Disease ENSG00000198793 PMC8326529__F9 Network Pharmacology Prediction and Molecular Docking-Based Strategy to Discover the Potential Pharmacological Mechanism of Huai Hua San Against Ulcerative Colitis ENSG00000177455 ENSG00000103479 ENSG00000186716 ENSG00000104894 PMC3035969__F5 Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression ENSG00000104856 ENSG00000087095 ENSG00000185652 ENSG00000172680 ENSG00000172380 ENSG00000169750 ENSG00000177606 ENSG00000136997 ENSG00000130159 ENSG00000127191 ENSG00000196712 ENSG00000026103 PMC8623546__F6 Nephronophthisis-Pathobiology and Molecular Pathogenesis of a Rare Kidney Genetic Disease ENSG00000115415 ENSG00000168610 PMC8623546__F7 Nephronophthisis-Pathobiology and Molecular Pathogenesis of a Rare Kidney Genetic Disease ENSG00000140463 ENSG00000134982 ENSG00000113971 ENSG00000174483 PMC4666325__F2 BCR signaling and downstream pathways ENSG00000186716 ENSG00000198793 ENSG00000010671 ENSG00000198286 PMC11743450__F3 Deregulated cell signaling pathways targeted by Bergenin ENSG00000198793 ENSG00000136869 ENSG00000168610 PMC8623546__F9 Nephronophthisis-Pathobiology and Molecular Pathogenesis of a Rare Kidney Genetic Disease ENSG00000128602 PMC8326529__F1 Network Pharmacology Prediction and Molecular Docking-Based Strategy to Discover the Potential Pharmacological Mechanism of Huai Hua San Against Ulcerative Colitis ENSG00000125538 ENSG00000177606 PMC6180204__F1 Negative effects of resveratrol on NFKB via several pathways in SCI ENSG00000137275 ENSG00000102871 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC7793647__F2 Major signaling pathways of GILZ ENSG00000144410 ENSG00000125538 ENSG00000177606 ENSG00000145321 PMC12108254__F2 Steps involved in irisin production and the molecular cascades underlying its biological functions ENSG00000132906 ENSG00000198793 ENSG00000136869 ENSG00000168610 ENSG00000198911 PMC8321552__F2 Kyoto Encyclopedia of Genes and Genomes (KEGG) for the nucleotide excision repair pathway ENSG00000108055 ENSG00000198793 ENSG00000196470 ENSG00000073111 ENSG00000277273 ENSG00000164305 ENSG00000276876 ENSG00000149311 ENSG00000175054 ENSG00000292191 ENSG00000113318 ENSG00000132646 ENSG00000136997 ENSG00000123374 ENSG00000112378 ENSG00000095002 ENSG00000136936 ENSG00000138385 ENSG00000122512 PMC9033023__F1 HSP90 mediates IFNGamma-induced adaptive immune resistance in pancreatic cancer ENSG00000159128 ENSG00000111537 ENSG00000115415 ENSG00000168785 ENSG00000027697 PMC3616003__F10 MicroRNA-301a Mediated Regulation of Kv4.2 in Diabetes: Identification of Key Modulators ENSG00000130037 ENSG00000123700 ENSG00000176842 ENSG00000141448 ENSG00000105711 ENSG00000285109 ENSG00000092054 ENSG00000182255 ENSG00000164093 ENSG00000197616 ENSG00000126778 ENSG00000081189 PMC6540009__F6 Scheme of the effect of pioglitazone on CKD-mediated ER stress in CKD-MSCs ENSG00000178860 ENSG00000128272 ENSG00000144895 ENSG00000171109 PMC2669301__F1 Tyrosine kinase network regulating mast cell activation ENSG00000157404 ENSG00000033327 ENSG00000115415 ENSG00000291971 ENSG00000010671 ENSG00000086730 ENSG00000141968 PMC3092918__F1 Metabolic network used for metabolic flux analysis ENSG00000138604 ENSG00000069482 ENSG00000122966 ENSG00000172005 PMC5884123__F8 Schematic diagram demonstrates the proliferation and apoptosis pathways including the upstream and downstream cascades activated by VEGFC in the GC-1 cells ENSG00000150630 PMC514912__F7 Model showing the cooperation of the BLM and the FA pathways in the response to replication arrest induced by either DNA crosslinks or UVC and HU exposure ENSG00000144554 ENSG00000197299 PMC11053446__F10 KEGG pathway analysis for DE mRNAs in tracheal tissues from chickens infected with IBV DMV/1639 or IBV Mass41 ENSG00000213928 ENSG00000168040 ENSG00000150455 ENSG00000143387 ENSG00000239732 ENSG00000144410 ENSG00000105397 ENSG00000170458 ENSG00000141086 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC4453937__F5 Summary of SIRT1 regulating the apoptotic upstream pathways within a cardiomyocyte in exercise-trained SD rats ENSG00000002330 ENSG00000026103 PMC8929692__F4 Major metabolic pathways upregulated in the cells utilizing 3-hydroxybenzoate, 4-hydroxybenzoate or hydroquinone as a sole carbon source ENSG00000169291 ENSG00000144410 ENSG00000174197 PMC10917925__F2 Pathways included in the model ENSG00000122966 ENSG00000291971 ENSG00000114315 PMC11513379__F2 Nanomedicine in HNSCC therapy-a challenge to conventional therapy ENSG00000163235 ENSG00000291971 ENSG00000149269 ENSG00000138798 ENSG00000132646 ENSG00000198793 ENSG00000168610 ENSG00000146648 ENSG00000140443 PMC2864453__F1 Nuclear factorKB (NFKB) can be activated by a multitude of different stimuli, like TNFA, LPS and CD40L ENSG00000104856 ENSG00000170458 ENSG00000136869 PMC7865812__F1 Contribution of transcription factors (TFs) to disease progression ENSG00000125398 ENSG00000005513 ENSG00000122691 ENSG00000136997 ENSG00000124766 ENSG00000129514 ENSG00000285438 ENSG00000100219 ENSG00000134595 ENSG00000139687 ENSG00000139352 ENSG00000110693 PMC7339106__F3 Tumor expressed CD200 inhibits the expansion of myeloid cells in TME ENSG00000091972 PMC4170615__F6 Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma ENSG00000177606 ENSG00000026103 PMC5472345__F1 The NAD+ salvage pathway and its control by the circadian clock ENSG00000105835 ENSG00000150907 ENSG00000177551 ENSG00000096717 ENSG00000168610 PMC4761106__F2 Hereditary Melanoma: Update on Syndromes and Management - Emerging melanoma cancer complexes and genetic counseling ENSG00000163930 ENSG00000164362 ENSG00000128513 ENSG00000102977 PMC10758965__F2 Regulatory mechanisms of one-carbon metabolism enzymes ENSG00000284320 ENSG00000228716 ENSG00000065978 ENSG00000128272 ENSG00000100714 ENSG00000092621 ENSG00000136997 ENSG00000135069 ENSG00000163738 ENSG00000146733 ENSG00000120254 ENSG00000116984 PMC3368374__F1 In young muscle, abundant serum IGF-I can stimulate protein synthesis by activating Akt/mTOR/p70S6K pathway ENSG00000198793 ENSG00000137563 PMC6739326__F8 Fibroblast growth factor 21 Ameliorates diabetes-induced endothelial dysfunction in mouse aorta via activation of the CaMKK2/AMPKA signaling pathway ENSG00000105550 ENSG00000110931 ENSG00000077782 PMC8880314__SF1 Cannabidiol Downregulates Myocardial de Novo Ceramide Synthesis Pathway in a Rat Model of High-Fat Diet-Induced Obesity ENSG00000063176 ENSG00000188611 ENSG00000119537 ENSG00000148154 PMC5164846__F2 Fine-tuning vascular fate during endothelial-mesenchymal transition PMC8697445__F1 Enhanced production of Gamma-amino acid 3-amino-4-hydroxybenzoic acid by recombinant Corynebacterium glutamicum under oxygen limitation ENSG00000122966 ENSG00000172005 PMC2292640__F1 SARS CORONAVIRUS AND INNATE IMMUNITY ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000130234 ENSG00000107201 ENSG00000131323 ENSG00000164342 ENSG00000142166 PMC8406474__F2 NRF2 signalling pathway: New insights and progress in the field of wound healing ENSG00000181019 ENSG00000178573 ENSG00000100387 ENSG00000079999 PMC8406474__F3 NRF2 signalling pathway: New insights and progress in the field of wound healing ENSG00000162711 ENSG00000156709 ENSG00000198793 ENSG00000142082 ENSG00000247077 ENSG00000079999 PMC6471541__F11 Proposed schematic depicting the signalling pathway via which TGFB1 promotes the osteogenesis and migration of osteoblasts ENSG00000087245 ENSG00000100985 PMC10758965__F3 Regulatory mechanisms of one-carbon metabolism enzymes ENSG00000128272 ENSG00000136997 ENSG00000162772 ENSG00000107077 PMC11018843__F4 Amyotrophic Lateral Sclerosis (ALS) and cytosolic DNA sensors ENSG00000183735 ENSG00000164430 ENSG00000110218 ENSG00000010671 ENSG00000147894 PMC10758965__F5 Regulatory mechanisms of one-carbon metabolism enzymes ENSG00000284320 ENSG00000228716 ENSG00000128050 ENSG00000100714 ENSG00000132646 ENSG00000136371 ENSG00000163738 ENSG00000120254 PMC11018843__F1 Main cytosolic DNA sensors and their downstream pathways ENSG00000124256 ENSG00000137275 ENSG00000163568 ENSG00000198793 ENSG00000163565 ENSG00000157954 ENSG00000168040 ENSG00000127191 ENSG00000010671 ENSG00000057663 ENSG00000169245 ENSG00000183735 ENSG00000108691 ENSG00000164430 ENSG00000176986 ENSG00000134824 ENSG00000006606 ENSG00000168404 ENSG00000285379 ENSG00000115009 PMC11018843__F2 Alzheimer’s disease (AD) and cytosolic DNA sensors ENSG00000169245 ENSG00000183735 ENSG00000164430 ENSG00000115415 ENSG00000163568 ENSG00000142166 PMC6070613__F8 Triptolide signaling pathway ENSG00000123374 ENSG00000026103 PMC11018843__F3 Parkinson’s disease (PD) and cytosolic DNA sensors ENSG00000183735 ENSG00000164430 ENSG00000130204 ENSG00000163568 ENSG00000163565 ENSG00000158828 ENSG00000142166 PMC6476043__F1 Proposed schematic representation of the immune response to MERS-CoV infection and how the invading virus is processed during an infection ENSG00000169245 ENSG00000113520 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC8484489__F3 AP2/ERF, an important cold stress-related transcription factor family in plants: A review ENSG00000105722 ENSG00000164151 ENSG00000110395 PMC4076637__F6 CDK4/6 is downstream of multiple pathways ENSG00000135446 ENSG00000105810 PMC5853807__F5 Proposed model of immunopathogenesis of Borreliella burgdorferi during early cutaneous infection ENSG00000174125 ENSG00000169248 ENSG00000143546 ENSG00000204577 ENSG00000163220 ENSG00000157601 ENSG00000129226 ENSG00000049768 ENSG00000274513 ENSG00000276561 ENSG00000169245 ENSG00000134321 ENSG00000138755 PMC11770944__F3 Relationship between common targets of wogonoside and AS therapy and the top 15 enriched targets of the KEGG signaling pathway ENSG00000149311 ENSG00000226275 ENSG00000213658 ENSG00000173039 ENSG00000073756 ENSG00000113448 PMC4836210__F4 Graphic representation of apoptosis signalling pathways ENSG00000102871 ENSG00000120868 ENSG00000168040 PMC5127718__F2 Endocytic Pathway in Microglia During Health, Aging and Alzheimer’s Disease ENSG00000003056 ENSG00000112561 ENSG00000081087 PMC5513689__F1 Alcohol’s effects on the hypothalamic–pituitary–adrenal (HPA) axis and the stress response ENSG00000150782 ENSG00000115138 PMC3712543__F4 Somatic variations in genes encoding proteins of the KEGG “Melanoma” signaling pathway ENSG00000002330 ENSG00000138798 ENSG00000077782 ENSG00000146648 ENSG00000127948 ENSG00000197461 PMC10778204__F2 Representation of the important miRNAs that effectively regulate the Notch signaling pathway in glioblastoma ENSG00000198382 ENSG00000148400 ENSG00000090932 PMC7415199__F2 Hypothetical diagram of the possible targets where melatonin may act against SARS-CoV-2 infection in the CNS ENSG00000162711 ENSG00000125538 ENSG00000184012 ENSG00000168610 PMC2898418__F10 Schematic pathway of IL-8-mediated NAADP formation by CD38 in LAK cells ENSG00000145321 ENSG00000137841 PMC4836210__F7 Graphic representation of apoptosis and viral replication ENSG00000002330 ENSG00000144895 ENSG00000102871 ENSG00000168040 ENSG00000135116 PMC11011519__F2 NFKB and JAK/STAT Signaling Pathways as Crucial Regulators of Neuroinflammation and Astrocyte Modulation in Spinal Cord Injury ENSG00000168610 PMC8741374__F4 Huanglian Jiedu Decoction Exerts Antipyretic Effect by Inhibiting MAPK Signaling Pathway ENSG00000050628 ENSG00000138798 ENSG00000173039 ENSG00000007908 ENSG00000171791 ENSG00000178726 ENSG00000132693 ENSG00000007171 ENSG00000104368 ENSG00000169245 ENSG00000108691 ENSG00000005421 ENSG00000149968 ENSG00000102245 ENSG00000136997 ENSG00000095303 ENSG00000164136 ENSG00000005381 ENSG00000139687 ENSG00000146648 PMC6563602__F1 Complement system as a biomarker of disease activity and response to treatment in multiple sclerosis ENSG00000039537 ENSG00000113600 ENSG00000288512 ENSG00000244731 ENSG00000166278 ENSG00000182326 ENSG00000236625 PMC5582909__F2 RAS pathway status in human DKD, based on urine concentration and enzymatic activity of RAS components ENSG00000064601 ENSG00000100448 ENSG00000130234 PMC6239977__F2 Calcium-calmodulin-calcineurn-NFaT-DYRK1A pathway to human beta cell proliferation ENSG00000129757 ENSG00000157540 PMC2592633__F1 RNAi pathways in Drosophila ENSG00000143194 ENSG00000092847 ENSG00000113360 ENSG00000123908 PMC10536099__F6 Interferon-λ Activates a Differential Response in Peripheral Neurons That Is Effective against Alpha Herpesvirus Infections ENSG00000213928 ENSG00000089127 ENSG00000115415 ENSG00000185436 ENSG00000185745 PMC3240659__F3 Repeated Small Perturbation Approach Reveals Transcriptomic Steady States ENSG00000117519 ENSG00000116717 ENSG00000111371 ENSG00000148154 ENSG00000073756 ENSG00000164305 ENSG00000124762 ENSG00000152518 ENSG00000166508 ENSG00000134531 PMC5897151__F3 Mitochondrial function and autophagy: integrating proteotoxic, redox, and metabolic stress in Parkinson’s disease ENSG00000172005 ENSG00000158828 ENSG00000112561 PMC5482974__F3 Protein traffic steps mediated by PACS-1 and PACS-2 ENSG00000140564 ENSG00000175115 ENSG00000165527 PMC5482974__F4 PACS-2 Akt site and NLS together modulate membrane traffic, TRAIL-induced apoptosis, MAM integrity and the response to DNA damage ENSG00000149311 ENSG00000138798 ENSG00000096717 PMC7692234__F4 Hypothetical host-cell signaling pathways linking Cryptosporidium parvum infection and tumorigenesis ENSG00000134982 ENSG00000140575 ENSG00000168036 PMC9099149__F1 Integrin Crosstalk and Its Effect on the Biological Functions of the Trabecular Meshwork/Schlemm’s Canal ENSG00000038382 ENSG00000156299 ENSG00000291971 PMC8457726__F1 Environmental Exposure to Heavy Metals Contributes to Diseases Via Deregulated Wnt Signaling Pathways ENSG00000167772 ENSG00000134982 ENSG00000167941 ENSG00000168036 ENSG00000185269 PMC8457726__F2 Environmental Exposure to Heavy Metals Contributes to Diseases Via Deregulated Wnt Signaling Pathways ENSG00000165556 ENSG00000181788 ENSG00000163914 ENSG00000168036 PMC4276949__F1 Hypothetical model of HGF/SF activation in cancer ENSG00000019991 ENSG00000137747 ENSG00000167749 ENSG00000167754 ENSG00000084110 PMC9641817__F4 Microbiota-derived tryptophan metabolites in vascular inflammation and cardiovascular disease PMC7312818__F3 Role of miRNAs in the host–pathogen interaction ENSG00000130234 ENSG00000172936 ENSG00000001626 ENSG00000175104 PMC11781169__F7 Proposed mechanism underlying TRIM32 in enhancing neuronal ferroptosis after SCI ENSG00000149311 ENSG00000119401 ENSG00000167468 PMC11673384__F1 Driver mechanisms of ferroptosis ENSG00000111684 ENSG00000115107 ENSG00000127948 PMC5494096__F4 Pipeline of cell cycle and MAPK signaling pathway ENSG00000108055 ENSG00000134982 ENSG00000156574 ENSG00000091651 ENSG00000277273 ENSG00000117399 ENSG00000276876 ENSG00000093009 ENSG00000145604 ENSG00000094804 ENSG00000111537 ENSG00000095739 ENSG00000132646 ENSG00000136997 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000164093 PMC4149353__F5 Systems-Based Analyses of Brain Regions Functionally Impacted in Parkinson's Disease Reveals Underlying Causal Mechanisms ENSG00000184060 ENSG00000220205 PMC6747522__F2 Canonical and non-canonical signaling of FGF23 ENSG00000118972 ENSG00000066468 ENSG00000160867 PMC9221492__F1 Synthetic Vulnerabilities in the KRAS Pathway ENSG00000068028 ENSG00000017797 ENSG00000070831 ENSG00000156299 ENSG00000198793 ENSG00000163914 ENSG00000165527 PMC7318172__F5 Graphic showing the signalling pathway by which SYT4 regulates melanogenesis via Ca2+ influx ENSG00000132872 ENSG00000152495 ENSG00000080166 ENSG00000134160 ENSG00000107165 PMC11845729__F5 Expression pattern of differentially expressed genes involved in the Wnt signalling pathway, an ancient and evolutionarily conserved pathway regulates the cell migration, polarity, neural patterning and organogenesis during embryonic development ENSG00000087095 ENSG00000134982 ENSG00000167941 ENSG00000113558 ENSG00000121058 ENSG00000158941 ENSG00000088926 PMC8238150__F1 (Pro)renin receptor in the kidney: function and significance ENSG00000167580 ENSG00000281324 ENSG00000197629 PMC3691184__F5 Integrated miRNA-mRNA Analysis Revealing the Potential Roles of miRNAs in Chordomas ENSG00000087095 ENSG00000127191 ENSG00000081189 ENSG00000026103 PMC2635127__F2 JNK/p38 non-Smad pathway ENSG00000175104 PMC2635127__F3 Small GTPase non-Smad pathway ENSG00000070831 PMC2635127__F1 Erk non-Smad pathway PMC11884060__F6 Map of the metabolic pathways related to the differentially expressed genes in strains S26 and S26-AE2 under 20 g/L and 100 g/L glucose conditions ENSG00000074800 PMC2635127__F4 PI3K/Akt non-Smad pathway ENSG00000198793 PMC8816882__F2 Programmed cell death in aortic aneurysm and dissection: A potential therapeutic target ENSG00000278718 ENSG00000162711 ENSG00000137275 ENSG00000167468 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC5607088__F1 AT1 receptor signaling pathways in the cardiovascular system ENSG00000113070 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8569258__F2 Panax ginseng and its ginsenosides: potential candidates for the prevention and treatment of chemotherapy-induced side effects ENSG00000171105 ENSG00000102871 ENSG00000198793 ENSG00000169710 ENSG00000171791 ENSG00000127191 PMC6048025__F8 Regulatory effects of androgen on TGFB1/Smad signaling pathway and Nrf2-ARE signaling pathway ENSG00000087245 ENSG00000181019 ENSG00000079999 PMC3514454__F7 Homocysteine upregulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo ENSG00000185591 PMC3425523__F4 Genes known to cause kidney cancer and their relationship with the mammalian target of rapamycin signaling pathway ENSG00000019991 ENSG00000134086 ENSG00000052795 ENSG00000217128 PMC10454862__F10 S100A4 Promotes BCG-Induced Pyroptosis of Macrophages by Activating the NFKB/NLRP3 Inflammasome Signaling Pathway ENSG00000278718 ENSG00000162711 ENSG00000196154 PMC4467434__F6 Recurrent SKIL-activating rearrangements in ETS-negative prostate cancer ENSG00000136603 ENSG00000107779 ENSG00000170365 ENSG00000173599 ENSG00000120693 ENSG00000204217 PMC2919370__F4 Fanconi Anemia Proteins and Endogenous Stresses ENSG00000175054 ENSG00000164053 ENSG00000187741 ENSG00000112039 PMC7728580__F2 Role of H2S in HCC ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC2757945__F9 Molecular pathways by which WNT-Beta-Catenin and FGF regulate lung mesenchymal development ENSG00000138795 ENSG00000168036 ENSG00000102678 PMC9174948__F3 Chloroplast pH Homeostasis for the Regulation of Photosynthesis ENSG00000060982 ENSG00000105552 PMC5684252__F1 An overview of signaling nexus of autophagy pathways ENSG00000177169 ENSG00000005893 ENSG00000070540 ENSG00000112561 ENSG00000171791 ENSG00000145782 ENSG00000057663 PMC2663408__F15 The Aldo-Keto Reductase Superfamily and its Role in Drug Metabolism and Detoxification ENSG00000151632 ENSG00000197838 ENSG00000198610 ENSG00000187134 PMC4063740__F8 Regulation of Schistosoma mansoni Development and Reproduction by the Mitogen-Activated Protein Kinase Signaling Pathway ENSG00000138798 ENSG00000146648 PMC7874400__F7 Critical role of miR-574-5p in ARDS pathogenesis ENSG00000162711 ENSG00000125538 ENSG00000189403 ENSG00000136869 PMC7226631__F6 miRNA networks generated using IPA (Ingenuity Pathway Analysis) for the altered plasma miRNAs in colorectal cancer ENSG00000171759 PMC6715616__F1 Anti‐ and proviral roles of autophagy in plants ENSG00000188554 ENSG00000088320 ENSG00000092847 PMC4868689__F7 Protein kinase D2 contributes to TNF-Alpha-induced epithelial mesenchymal transition and invasion via the PI3K/GSK-3B/Beta-catenin pathway in hepatocellular carcinoma ENSG00000168036 PMC11009445__F1 Emerging role of lncRNAs as mechanical signaling molecules in mechanotransduction and their association with Hippo-YAP signaling: a review ENSG00000163914 ENSG00000150457 ENSG00000131023 ENSG00000026103 PMC9336466__F2 Drosophila Innate Immunity Involves Multiple Signaling Pathways and Coordinated Communication Between Different Tissues ENSG00000213658 ENSG00000162924 ENSG00000168040 PMC7455639__F1 Genetic variant rs2494938 of LRFN2 gene is associated with non-small cell lung cancer risk in North-Indian population ENSG00000156564 ENSG00000134982 ENSG00000132535 PMC4690755__F6 Novel pathways of apolipoprotein A-I metabolism in HDL of different sizes in humans ENSG00000042832 ENSG00000100979 ENSG00000172350 ENSG00000160179 PMC11822051__F6 The proposed mechanism ENSG00000129219 ENSG00000198793 ENSG00000173599 PMC1413672__F6 Activation of PI3K signaling by PV ENSG00000198793 PMC5423755__F1 FA/BRCA DNA damage response pathway ENSG00000136492 ENSG00000083093 ENSG00000108384 ENSG00000162607 ENSG00000051180 ENSG00000139618 PMC3613856__F7 Association of Luteinizing hormone receptor (LHR) mRNA with its binding protein leads to decapping and degradation of the mRNA in the p bodies ENSG00000172795 ENSG00000272886 PMC12235269__F3 Fig. 3. JAK-STAT signalling pathway and JAK inhibitors in ulcerative colitis ENSG00000099985 ENSG00000105397 ENSG00000128342 ENSG00000105639 ENSG00000142224 PMC7795031__F1 Shows how AhR ligands, such as air pollutants, FICZ, TCDD and kynurenine, including tumour derived, activate the AhR to modulate mitochondrial metabolism, partly via the regulation of the melatonergic pathway ENSG00000106546 PMC8909928__F1 Fibroblast Growth Factor 23 and Osteoporosis: Evidence from Bench to Bedside ENSG00000118972 ENSG00000152266 ENSG00000036828 PMC6908928__F9 Gene network describing the possible mechanism of the regulation by CHST15 of cell proliferation and apoptosis as determined by IPA ENSG00000100234 ENSG00000154856 ENSG00000132323 ENSG00000142230 ENSG00000163235 ENSG00000159388 ENSG00000120885 ENSG00000196642 ENSG00000138768 ENSG00000095794 ENSG00000140416 PMC9500187__F2 Transcriptional regulation of INK4/ARF locus by cis and trans mechanisms ENSG00000135446 ENSG00000105810 PMC6581700__F6 Molecular model for HTLV-1 and HTLV-2 regulatory proteins HBZ and APH-2 on Tax-mediated NFKB activation and TRAF3 interaction ENSG00000130656 ENSG00000131323 PMC4715896__F1 Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis ENSG00000132423 ENSG00000173085 ENSG00000167186 PMC8814816__F2 Targeting cholesterol homeostasis in hematopoietic malignancies ENSG00000110921 ENSG00000138135 ENSG00000036530 ENSG00000135929 PMC8589410__F10 Proteomic profiling of saliva reveals association of complement system with primary Sjögren's syndrome ENSG00000171560 PMC3429540__F1 Emerging role of autophagy in kidney function, diseases and aging ENSG00000155876 ENSG00000187840 PMC6349439__F1 We shall overcome (drug resistance) some day ENSG00000168610 ENSG00000146648 PMC2909662__F1 Signaling pathways of TLR4 ENSG00000174125 ENSG00000172005 ENSG00000173039 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC6827255__F1 DNA-driven cGAS-cGAMP-STING signaling mediates innate immune response ENSG00000183735 ENSG00000213928 ENSG00000164430 ENSG00000115415 PMC7532048__F9 Mechanism diagram ENSG00000117139 ENSG00000168036 PMC3436837__F1 Boolean network model of the HGF-induced keratinocyte migration ENSG00000019991 ENSG00000033327 ENSG00000070831 ENSG00000113070 ENSG00000123374 ENSG00000166670 ENSG00000146648 ENSG00000122194 ENSG00000115009 PMC5618532__F2A Histone Deacetylase Inhibitor-Induced Autophagy in Tumor Cells: Implications for p53 ENSG00000177169 ENSG00000198793 ENSG00000171791 PMC5727250__F3 Possible Wnt pathway‐related therapeutic targets in CLL ENSG00000138795 ENSG00000185483 ENSG00000168036 PMC6939831__F4 Three enriched Ca2+-related pathways ENSG00000137713 ENSG00000134982 ENSG00000198626 ENSG00000157240 ENSG00000136068 PMC4661858__F3 Inhibitors developed against EZH2 ENSG00000139154 ENSG00000074266 PMC5727250__F1 Simplified overview of mammalian Wnt/B‐catenin and Wnt/PCP pathways ENSG00000138795 ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000136997 ENSG00000185483 ENSG00000168036 PMC4766307__F1 Recruitment and activation of bone marrow-derived fibroblasts in renal fibrosis ENSG00000108691 ENSG00000161921 ENSG00000137077 ENSG00000105639 PMC9248407__F3 Detection of tumor-specific DNA methylation markers in the blood of patients with pituitary neuroendocrine tumors ENSG00000126775 ENSG00000196549 ENSG00000105516 ENSG00000183020 ENSG00000198691 PMC11052371__F3 Pathogenesis of acne and the mechanism of action of P ENSG00000066468 ENSG00000070193 ENSG00000135218 ENSG00000198793 ENSG00000140285 ENSG00000168036 ENSG00000162692 PMC3173801__F1 Many receptors modulate Wnt signalling ENSG00000112655 ENSG00000168036 PMC9112182__F7 RNA Binding Motif Protein 3 Promotes Cell Metastasis and Epithelial–Mesenchymal Transition Through STAT3 Signaling Pathway in Hepatocellular Carcinoma ENSG00000087245 ENSG00000102317 ENSG00000100985 ENSG00000168610 PMC3726314__F6 Toll-Like Receptor 4-Myeloid Differentiation Factor 88 Signaling Contributes to Ventilator-induced Lung Injury in Mice ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC3557433__F1 Effector intercrossing network under physiological condition ENSG00000042832 ENSG00000182759 ENSG00000175567 ENSG00000096717 ENSG00000165795 PMC6467343__F1 Complications and management of coagulation disorders in leukemia patients ENSG00000160752 ENSG00000003436 ENSG00000122194 ENSG00000062485 PMC5496628__F1 mTOR is the essential signaling pathway for nutrient sensing and apoptosis protection in the B cell ENSG00000169047 ENSG00000265972 PMC3384424__F1 The mTOR signaling pathway ENSG00000155792 ENSG00000186654 PMC6679057__F2 WNT pathway molecules and their involvement in chemoresistance in NB ENSG00000168036 ENSG00000157240 PMC10886236__F4 Heatmap of the pathway of glycolysis, antioxidant enzymes, and ascorbate–glutathione cycle ENSG00000109814 ENSG00000196531 ENSG00000105227 PMC9206138__F2 Immunosuppressive role of indoleamine 2, 3-dioxygenase in glioblastoma: mechanism of action and immunotherapeutic strategies PMC5396079__F10 Critical role of SCD1 in autophagy regulation via lipogenesis and lipid rafts-coupled AKT-FOXO1 signaling pathway ENSG00000150907 ENSG00000145782 PMC7010219__F7 Role of DADS in leukemia cells ENSG00000106683 ENSG00000067900 PMC7733924__F6 Predicted pathways might be involved in the interaction between CSFV p7 and host cells ENSG00000101367 ENSG00000275099 ENSG00000033800 ENSG00000132963 PMC11707400__F5 Immune signaling pathway of infected cells ENSG00000174125 ENSG00000239732 ENSG00000164430 ENSG00000130234 ENSG00000184012 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 PMC6535662__F1 Various regulatory mechanisms of MALAT1 in different diabetes-related complications ENSG00000162711 ENSG00000066044 ENSG00000168036 ENSG00000172936 ENSG00000185591 PMC1190322__F10 CdGAP mediates cross talk between the Ras/MAPK pathway and the regulation of Rac1 activity ENSG00000169291 ENSG00000156299 PMC3573943__F1 Regulation of cellular metabolism by p53 ENSG00000135423 ENSG00000005882 ENSG00000078237 ENSG00000284194 PMC4509205__F4 PI3K/AKT network in renal cancer samples ENSG00000002330 ENSG00000177606 ENSG00000136997 ENSG00000196712 PMC5332432__F1 Activation and control mechanisms of the human complement system PMC9187795__F3 CD30 Expression in Oral and Oropharyngeal Diffuse Large B Cell Lymphoma, not Otherwise Specified ENSG00000102871 ENSG00000082512 ENSG00000157625 ENSG00000127191 PMC5618532__F1A Histone Deacetylase Inhibitor-Induced Autophagy in Tumor Cells: Implications for p53 ENSG00000177169 ENSG00000198793 ENSG00000171791 PMC6359975__F2 Acquired resistance mechanisms to CDK4/6 targeting ENSG00000002330 ENSG00000157764 ENSG00000135446 ENSG00000123374 PMC7349579__F2 Interactions of LCSCs influencing HCC ENSG00000281324 ENSG00000162337 ENSG00000119888 ENSG00000134982 ENSG00000272398 ENSG00000168036 ENSG00000168610 PMC8146608__F4 Influenza Virus RNA Synthesis and the Innate Immune Response ENSG00000124256 ENSG00000183735 ENSG00000088888 ENSG00000168404 ENSG00000121060 ENSG00000276561 ENSG00000285379 PMC8394812__F1 Evolution of Cellular Immunity Effector Cells; Perspective on Cytotoxic and Phagocytic Cellular Lineages ENSG00000135218 ENSG00000157625 ENSG00000175104 PMC2258989__F6 Schematic presentation of the signaling pathway induced by HCV core protein for insulin resistance in human hepatocytes ENSG00000124102 ENSG00000169047 ENSG00000198793 PMC2840099__F7 Proposed model of miR-486 regulation and function in muscle cells PMC8699052__F2 NRF2 in Mycobacterial Infection ENSG00000175793 ENSG00000115415 ENSG00000121807 PMC5076847__F12 Regulation of IRF1 and IRF1-dependent late-phase gene expression by IL1B after DUSP1 silencing and glucocorticoid treatment ENSG00000150782 ENSG00000125538 ENSG00000145321 ENSG00000125347 PMC8507617__F1 Hedgehog Signaling in Myeloid Malignancies ENSG00000128602 PMC10223558__F6 Identification of key hub genes ENSG00000204262 ENSG00000053747 ENSG00000106070 ENSG00000136997 ENSG00000100078 ENSG00000108821 ENSG00000162552 ENSG00000145824 ENSG00000170899 ENSG00000163431 ENSG00000185745 ENSG00000204531 ENSG00000152689 ENSG00000091879 ENSG00000151388 ENSG00000169245 ENSG00000186810 ENSG00000261371 ENSG00000170962 ENSG00000169220 ENSG00000163710 ENSG00000085871 ENSG00000174059 ENSG00000174156 ENSG00000107562 ENSG00000119508 ENSG00000121966 ENSG00000132965 ENSG00000136457 ENSG00000029559 ENSG00000011422 ENSG00000186340 ENSG00000149968 ENSG00000115457 ENSG00000146678 ENSG00000111186 ENSG00000197081 ENSG00000169896 ENSG00000285109 ENSG00000178363 ENSG00000182621 ENSG00000108691 ENSG00000281614 ENSG00000176884 ENSG00000178031 ENSG00000162409 ENSG00000158457 ENSG00000291748 ENSG00000100784 ENSG00000049089 PMC8814816__F1 Targeting cholesterol homeostasis in hematopoietic malignancies ENSG00000160179 PMC10223558__F5 Networking among differentially expressed genes (DEGs) and pathways identified via GSEA ENSG00000203786 ENSG00000008438 ENSG00000111344 ENSG00000158578 ENSG00000204021 ENSG00000182985 ENSG00000138356 ENSG00000053747 ENSG00000068976 ENSG00000106070 ENSG00000136997 ENSG00000100078 ENSG00000005187 ENSG00000165695 ENSG00000162896 ENSG00000162552 ENSG00000170899 ENSG00000153976 ENSG00000144810 ENSG00000152689 ENSG00000133401 ENSG00000276920 ENSG00000091879 ENSG00000116882 ENSG00000172508 ENSG00000138735 ENSG00000108839 ENSG00000189283 ENSG00000169245 ENSG00000170962 ENSG00000169220 ENSG00000164161 ENSG00000172986 ENSG00000146648 ENSG00000163082 ENSG00000174156 ENSG00000144063 ENSG00000134339 ENSG00000165996 ENSG00000146215 ENSG00000119508 ENSG00000276559 ENSG00000167363 ENSG00000114737 ENSG00000175592 ENSG00000167889 ENSG00000173702 ENSG00000132965 ENSG00000136457 ENSG00000029559 ENSG00000186340 ENSG00000149968 ENSG00000177191 ENSG00000111186 ENSG00000118520 ENSG00000101213 ENSG00000116748 ENSG00000169896 ENSG00000140263 ENSG00000158458 ENSG00000182621 ENSG00000100664 ENSG00000171596 ENSG00000147145 ENSG00000108691 ENSG00000281614 ENSG00000176884 ENSG00000198435 ENSG00000162409 ENSG00000167600 ENSG00000162390 ENSG00000291748 ENSG00000132746 ENSG00000100784 ENSG00000135702 ENSG00000122121 ENSG00000171004 ENSG00000198488 ENSG00000185973 ENSG00000155629 ENSG00000196407 ENSG00000171408 ENSG00000049089 PMC10223558__F8 Expression analysis of genes involved in PI3-AKT-mTOR pathway post MMTV expression ENSG00000132906 ENSG00000162552 ENSG00000002330 ENSG00000105401 ENSG00000198793 ENSG00000169047 ENSG00000152689 ENSG00000091879 ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000170962 ENSG00000186716 ENSG00000136997 ENSG00000136869 ENSG00000108821 PMC5850946__F7 Ras signaling cross-talk protein transport ENSG00000066468 ENSG00000157557 ENSG00000160867 ENSG00000163902 ENSG00000128052 ENSG00000134853 ENSG00000170348 ENSG00000164690 ENSG00000140464 ENSG00000292366 PMC7990793__F2 Differences of inhibitory effects between homodimeric and heterodimeric IL-35 ENSG00000138378 ENSG00000105397 ENSG00000105246 PMC6214138__F2 Canonical FLT3 and mutant FLT3 signaling pathways ENSG00000122025 ENSG00000169291 ENSG00000002330 ENSG00000198793 ENSG00000119383 PMC4484229__F5 Serum C1 competes with Wnt for Fz receptor binding, resulting in Wnt canonical pathway activation ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6499694__F7 Working model of how the spatial distribution of nuclear DNA damage and extracellular neurotrophic factor signaling coordinates AKT-mTORC1 activation ENSG00000149311 ENSG00000081913 PMC11449287__F12 D2O on expression levels of cellular genes involved in “TNF signaling pathway” and “p53 signaling pathway” ENSG00000149311 ENSG00000179091 ENSG00000135446 ENSG00000136997 ENSG00000198517 ENSG00000042286 ENSG00000123374 ENSG00000087842 PMC4111749__F2 Regulation and roles of Cdc7 kinase under replication stress ENSG00000144554 ENSG00000108384 ENSG00000070950 ENSG00000130997 PMC5850946__F5 PI3K-Akt signaling and Ras signaling pathways ENSG00000066468 ENSG00000073711 ENSG00000160867 ENSG00000163558 ENSG00000128052 PMC7068268__F3 Comprehensive circular RNA profiling reveals the regulatory role of circ_100242/miR-145 pathway in bladder cancer ENSG00000079432 PMC6468621__F3 Lung adenocarcinoma treatment and emerging therapeutic potential of targeting macrophages ENSG00000108691 ENSG00000107562 PMC7530006__F2 Schematic Indicating Common Pattern Recognition Receptor (PRR) Pathways Used by Immune Cells to Recognize Danger Signals ENSG00000174125 ENSG00000162711 ENSG00000163568 ENSG00000171051 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000187554 ENSG00000125538 ENSG00000136869 ENSG00000172936 ENSG00000164342 PMC5438623__F7 Screening effective differential expression genes for hepatic carcinoma with metastasis in the peripheral blood mononuclear cells by RNA-seq ENSG00000125538 ENSG00000177606 ENSG00000100985 PMC4773219__F6 Rare Copy Number Variants Identified Suggest the Regulating Pathways in Hypertension-Related Left Ventricular Hypertrophy ENSG00000116871 ENSG00000160094 ENSG00000037897 ENSG00000275111 ENSG00000101441 ENSG00000162396 ENSG00000284869 ENSG00000164796 ENSG00000132763 ENSG00000166278 ENSG00000291442 ENSG00000116984 ENSG00000150991 ENSG00000132781 ENSG00000173898 ENSG00000006451 ENSG00000129103 ENSG00000040531 PMC4773219__F4 Rare Copy Number Variants Identified Suggest the Regulating Pathways in Hypertension-Related Left Ventricular Hypertrophy ENSG00000150991 ENSG00000184384 PMC9247483__F2 Current Understanding and Management of Plasma Cell Mastitis: Can We Benefit from What We Know? ENSG00000120833 ENSG00000112964 ENSG00000198793 ENSG00000168610 PMC9000380__F1 Ferroptosis: A New Road towards Cancer Management ENSG00000167468 ENSG00000111684 PMC545204__F3 Retinoic Acid and Arsenic for Treating Acute Promyelocytic Leukemia ENSG00000122025 ENSG00000140464 PMC9063252__F8 Effects of SARS-CoV-2 infection on modulating innate immunity and strategies of combating inflammatory response for COVID-19 therapy ENSG00000115977 ENSG00000130234 ENSG00000196591 PMC11046879__F2 Illustrates the functions of PTEN in the cytoplasm and nucleus ENSG00000145241 ENSG00000198793 ENSG00000132383 ENSG00000051180 ENSG00000073111 PMC8188603__F7 Network Pharmacology and Molecular Docking Study on the Potential Mechanism of Yi-Qi-Huo-Xue-Tong-Luo Formula in Treating Diabetic Peripheral Neuropathy ENSG00000142192 ENSG00000173599 PMC3507431__F2 Mitochondria as a Drug Target in Ischemic Heart Disease and Cardiomyopathy ENSG00000291971 ENSG00000198793 ENSG00000096717 PMC7273913__F1 Characterization of FANCL variants observed in patient cancer cells ENSG00000144554 ENSG00000077152 ENSG00000115392 PMC7527441__F1 Major immune response pathways after helminth infection ENSG00000291363 ENSG00000137033 ENSG00000109321 ENSG00000105656 ENSG00000145777 ENSG00000118520 ENSG00000166090 PMC8405290__F5 Exploring the Mechanism of Action of Herbal Medicine (Gan-Mai-Da-Zao Decoction) for Poststroke Depression Based on Network Pharmacology and Molecular Docking ENSG00000284774 ENSG00000140279 ENSG00000169710 ENSG00000171791 ENSG00000069667 ENSG00000183765 ENSG00000068976 ENSG00000136997 ENSG00000108821 ENSG00000139687 ENSG00000087245 ENSG00000142192 ENSG00000213341 ENSG00000007908 ENSG00000166670 ENSG00000043591 ENSG00000132170 ENSG00000169245 ENSG00000170961 ENSG00000118785 ENSG00000138823 ENSG00000182240 ENSG00000146648 ENSG00000127948 ENSG00000169248 ENSG00000002330 ENSG00000140505 ENSG00000087085 ENSG00000113161 ENSG00000124107 ENSG00000158517 ENSG00000148344 ENSG00000145386 ENSG00000112715 ENSG00000118777 ENSG00000106546 ENSG00000276825 ENSG00000150782 ENSG00000117525 ENSG00000130164 ENSG00000149968 ENSG00000123374 ENSG00000120903 ENSG00000132906 ENSG00000104365 ENSG00000081041 ENSG00000173039 ENSG00000140465 ENSG00000073756 ENSG00000168610 ENSG00000108691 ENSG00000134057 ENSG00000135446 ENSG00000177606 ENSG00000057593 ENSG00000291748 ENSG00000100985 ENSG00000005381 ENSG00000159399 PMC7990793__F4 Potential working model of IL-35 immunepathogenesis in chronic HBV infection ENSG00000138378 ENSG00000105397 ENSG00000105246 PMC1236700__F2 Regulation of the extrinsic pathway by Hsps ENSG00000002330 ENSG00000102871 ENSG00000105401 ENSG00000056558 ENSG00000171791 ENSG00000168040 ENSG00000127191 ENSG00000104081 PMC5353654__F7 Series of functions (e.g ENSG00000170893 ENSG00000171560 PMC5260050__F2 Pathway map for selected proteins encoded by genes that were upregulated in baseline systemic juvenile idiopathic arthritis (SJIA) samples ENSG00000115415 ENSG00000177606 ENSG00000172936 ENSG00000125347 ENSG00000175104 ENSG00000184216 PMC5593568__F7 IL-8 promotes inflammatory mediators and stimulates activation of p38 MAPK/ERK-NFKB pathway and reduction of JNK in HNSCC ENSG00000163464 ENSG00000106100 PMC9394511__F9 Schematic model illustrating the PI3K/AKT pathway associated with CCRL25/CCR9-induced malignant biological behavior in SACC ENSG00000131142 ENSG00000171791 PMC5908625__F2 Identification of genes related to consecutive trauma-induced sepsis via gene expression profiling analysis ENSG00000070087 ENSG00000106123 ENSG00000108947 ENSG00000164091 ENSG00000106299 ENSG00000171475 ENSG00000188342 ENSG00000090776 ENSG00000138071 ENSG00000138778 ENSG00000196411 ENSG00000101161 ENSG00000011304 ENSG00000099995 ENSG00000090060 ENSG00000197299 ENSG00000285049 ENSG00000165494 PMC11648720__F8 Schematic diagram shows that two residues change in SARS-CoV-2 N protein trigger NFKB inhibition ENSG00000088888 ENSG00000137275 ENSG00000102871 ENSG00000082512 ENSG00000184012 ENSG00000172936 ENSG00000157625 ENSG00000166278 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC3120937__F1 Signalling pathways in oesophageal adenocarcinoma ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC4969253__F1 Retinoid regulation of early lung development ENSG00000070193 PMC8618769__F2 Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases ENSG00000138075 ENSG00000015520 ENSG00000160179 ENSG00000143921 PMC6562528__F7 PyCyp protein effects on EGFR signaling in IEC-6 cells ENSG00000123374 ENSG00000146648 PMC8618769__F5 Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases ENSG00000114200 ENSG00000142192 ENSG00000087085 PMC7952444__F4 Aberrant expression of PIWIL1 mediates tumorigenesis and progression ENSG00000168283 ENSG00000170558 ENSG00000198793 ENSG00000275051 PMC4763541__F7 Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation ENSG00000173599 ENSG00000164690 ENSG00000128602 PMC6563508__F5 Cytosolic recognition of foreign nucleic acids and activation of interferon stimulated genes (ISGs) ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000187608 ENSG00000105397 ENSG00000115415 ENSG00000276561 ENSG00000142166 PMC6357196__F5 Proposed chemoresistance mechanism mediated by RAB7A ENSG00000163624 ENSG00000110651 ENSG00000010278 ENSG00000135404 PMC6325590__F6 Leptin signaling modulates appetite through primary cilia ENSG00000115138 ENSG00000166603 ENSG00000168610 PMC3929886__F8 Model for JMJD2B silencing on tumour suppression through DNA damage ENSG00000149311 ENSG00000175054 ENSG00000168610 PMC6325590__F8 Mechanisms underlying the loss of primary cilia frequently observed in cancer cells with aberrant RTK ENSG00000154914 PMC11942745__F3 Putative schematic representation of the mTOR signaling pathway in APS ENSG00000155792 ENSG00000167965 PMC8809118__F7 NOX4 stimulates ANF secretion via activation of the Sirt1/Nrf2/ATF3/4 axis in hypoxic beating rat atria ENSG00000071564 ENSG00000138795 ENSG00000128272 ENSG00000086991 ENSG00000162772 ENSG00000096717 ENSG00000196628 ENSG00000079999 PMC12093350__F1 P2X7R in Retinal Diseases: A Review ENSG00000278718 ENSG00000162711 PMC5023632__F9 Possible mechanism for cross talk between P2X7 nucleotide receptor and canonical Wnt signaling pathways in cells of the osteoblast lineage ENSG00000154342 ENSG00000168036 PMC8834850__F2 Functional Roles of JNK and p38 MAPK Signaling in Nasopharyngeal Carcinoma ENSG00000115415 ENSG00000168610 PMC6268005__F2 ERAD regulation of cholesterol metabolism ENSG00000113161 ENSG00000120942 ENSG00000165280 ENSG00000184787 PMC8834850__F3 Functional Roles of JNK and p38 MAPK Signaling in Nasopharyngeal Carcinoma ENSG00000115415 ENSG00000136997 ENSG00000123268 PMC3404840__F1 HIV pathogenesis and T-cell signaling by HIV-1 Nef ENSG00000102871 ENSG00000056558 ENSG00000168040 ENSG00000127191 ENSG00000121966 ENSG00000026103 PMC3404840__F2 Modulation of HIV pathogenesis and T-cell signaling by HIV-1 Nef ENSG00000134982 PMC8895153__F3 SUMOylation in Viral Replication and Antiviral Defense ENSG00000079387 ENSG00000163904 ENSG00000183735 ENSG00000088888 ENSG00000197579 ENSG00000112343 ENSG00000276561 ENSG00000130726 PMC8687743__F2 HDAC6 and Its Selective Inhibitors in Gastrointestinal Cancer ENSG00000094631 ENSG00000284774 ENSG00000165280 PMC8895153__F4 SUMOylation in Viral Replication and Antiviral Defense ENSG00000163904 ENSG00000183735 ENSG00000164430 ENSG00000112343 ENSG00000138468 ENSG00000116030 ENSG00000184900 PMC4614078__F9 Updated model showing the role of AMPK-HDAC5 in HIF-1 activation as a response to hypoxia ENSG00000134086 ENSG00000197429 ENSG00000108840 PMC6073502__F4A Time Dependent Pathway Activation of Signalling Cascades in Rat Organs after Short-Term Hyperoxia ENSG00000168028 ENSG00000115091 ENSG00000179091 ENSG00000221914 ENSG00000143198 ENSG00000089157 ENSG00000167552 ENSG00000112818 ENSG00000165283 ENSG00000168610 ENSG00000087460 ENSG00000131143 ENSG00000120742 ENSG00000074800 ENSG00000133961 ENSG00000075239 ENSG00000136872 ENSG00000146701 ENSG00000184900 ENSG00000119125 PMC2964899__F1 Schematic representation of the molecular events associated with cellular processing, lipid modification, and secretion of the SHH protein and the autocrine and paracrine actions of mature and secreted SHH protein ENSG00000164690 ENSG00000128602 PMC5761609__F3 Activation signals of inflammasomes ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC2964899__F3 Molecular events associated with the repressive effect induced by PTCH1 receptor on the SMO activity and the activation of the Hh signaling pathway mediated by the SHH protein in the primary cilium ENSG00000164690 ENSG00000128602 PMC5646344__F1 Domain structure of Sina/Siah and its regulation in Drosophila and mammals ENSG00000149311 ENSG00000175054 ENSG00000157557 ENSG00000181788 ENSG00000122691 ENSG00000064393 ENSG00000185591 ENSG00000127334 PMC2964899__F5 Cellular events and signaling elements involved in the regulation of SHH expression, GLI activation, and mediation of the Hh activation-induced cellular response ENSG00000115008 ENSG00000138798 ENSG00000134853 ENSG00000168036 ENSG00000164690 ENSG00000146648 ENSG00000069667 PMC8226934__F2 Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling ENSG00000110395 ENSG00000074319 PMC2964899__F6 Scheme showing the signaling elements and frequent deregulations in the Hh signaling network and potential cross-talk with the EGFR signaling pathway involved in the malignant behavior of cancer cells ENSG00000164161 ENSG00000164690 ENSG00000128602 PMC7360675__F1 Extracellular and intracellular regulatory mechanisms of HLA-G expression ENSG00000276051 ENSG00000292357 ENSG00000125347 PMC8226934__F1 Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling ENSG00000198793 ENSG00000115290 PMC8904974__F8 Down regulated oncogene KIF2C inhibits growth, invasion, and metastasis of hepatocellular carcinoma through the Ras/MAPK signaling pathway and epithelial-to-mesenchymal transition PMC10036181__F4 Molecular and Cellular Crosstalk between Bone and Brain: Accessing Bidirectional Neural and Musculoskeletal Signaling during Aging and Disease ENSG00000118972 ENSG00000148346 ENSG00000167941 PMC10888037__F8 Schematic diagram showing the potential pathways which were more active in non-mucilage BS ENSG00000182511 ENSG00000073578 ENSG00000105953 ENSG00000073111 ENSG00000076003 ENSG00000133119 ENSG00000091140 ENSG00000062485 PMC5694782__F1 Critical DDR Pathways for UV induced DNA Damage: (1) UV induces an intrastrand lesion, causing the replication fork to stall in S-pase ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000132646 ENSG00000130997 ENSG00000051180 ENSG00000177084 ENSG00000139618 PMC7937872__F7 Proposed resisting the excitability toxicity signaling pathways triggered by ICT in ischemic neurons ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC6036739__F7 The positive feedback of CCL2 and SQSTM1 contributes to chemoresistance ENSG00000108691 ENSG00000198793 ENSG00000284099 ENSG00000121807 PMC5393948__F6 Isl1 conditional mutants are deficient in Foxo signaling ENSG00000150907 ENSG00000281518 ENSG00000112182 ENSG00000016082 PMC2601639__F1 Membrane Recruitment as a Cancer Mechanism: A Case Study of Akt PH Domain ENSG00000166278 PMC10743075__F9 N-3-PUFAs decreased mRNA expression of key enzymes of fatty acid biosynthetic pathway ENSG00000182511 ENSG00000213614 ENSG00000169710 PMC6550088__F2 Focal adhesion pathway (A) and HIF-1 signaling pathway (B) altered in a CRC ENSG00000169291 ENSG00000074800 ENSG00000002330 ENSG00000070831 ENSG00000198517 ENSG00000091409 ENSG00000101608 PMC8047536__F3 Intracellular interferon signalling pathways as potential regulators of covalently closed circular DNA in the treatment of chronic hepatitis B ENSG00000120833 ENSG00000163565 ENSG00000126457 ENSG00000111321 ENSG00000172183 PMC8450407__F3 TRIM21/Ro52 - Roles in Innate Immunity and Autoimmune Disease ENSG00000132109 ENSG00000213928 ENSG00000239732 ENSG00000105397 ENSG00000115415 ENSG00000140968 ENSG00000137265 ENSG00000168310 ENSG00000125347 ENSG00000276561 PMC2427336__F9 A schematic summarizing ER stress response pathways in cells compensating for deficiency of the ER stress response kinase, PERK ENSG00000128272 ENSG00000100219 PMC5355696__F3 Signaling pathway networks ENSG00000291971 ENSG00000128052 ENSG00000164327 ENSG00000188130 ENSG00000131196 ENSG00000089159 PMC7527241__F7 Serum discrimination and phenotype assessment of coronary artery disease patents with and without type 2 diabetes prior to coronary artery bypass graft surgery ENSG00000188641 ENSG00000124789 ENSG00000142798 ENSG00000197892 ENSG00000110799 ENSG00000121904 ENSG00000132466 ENSG00000138829 ENSG00000189056 ENSG00000163083 ENSG00000169876 ENSG00000144229 ENSG00000204740 ENSG00000165506 ENSG00000101152 ENSG00000104133 ENSG00000007402 ENSG00000131018 ENSG00000107611 ENSG00000117983 ENSG00000145244 ENSG00000155657 ENSG00000293532 PMC5223280__F5 Growth Arrest-Specific 6 (GAS6) Promotes Prostate Cancer Survival by G1 Arrest/S Phase Delay and Inhibition of Apoptotic Pathway During Chemotherapy in Bone Marrow ENSG00000135446 ENSG00000123374 PMC5688152__F7 Schematic overview of metabolic pathways of P ENSG00000102977 ENSG00000062485 PMC10513393__F5 Cytokine-mediated signaling in T-cell lymphoma metabolic reprogramming ENSG00000162594 ENSG00000198793 ENSG00000103522 PMC7827558__F1 Schema of the new arm of the DNA damage signaling pathway (DDR) ENSG00000115875 ENSG00000153046 ENSG00000161970 ENSG00000096717 PMC8798197__F5 Increased efficacy of gefitinib on cisplatin-resistant wild-type epidermal growth factor receptor non-small cell lung cancer cells ENSG00000002330 ENSG00000146648 PMC7830477__F7 Proposed mechanisms of the antioxidative actions of Pistacia lentiscus var PMC4797633__F1 Complement system ENSG00000203710 ENSG00000244731 PMC8861859__F7 Wheat oligopeptides enhance the intestinal mucosal barrier and alleviate inflammation via the TLR4/Myd88/MAPK signaling pathway in aged mice ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC3603280__F1 SLC41 family of MgtE-like magnesium transporters ENSG00000136052 ENSG00000092439 ENSG00000102158 ENSG00000174197 ENSG00000124181 PMC9755961__F3 Heterogeneity of neutrophils in cancer: one size does not fit all ENSG00000019991 ENSG00000198053 ENSG00000118520 PMC11967956__F7 Summary scheme of the obtained data ENSG00000198793 ENSG00000112715 PMC6058924__F6 Pathway Studio Analysis of Proteomic Content of TFMPs at 6 Months in the Infarcted Groups Compared With Control Group Profile(A) Heat shock proteins (HSPs) associated with post-ischemic conditioning detected in CRT+BB–treated animals only ENSG00000163399 PMC12006078__F6 Potential mechanisms of acacetin in preventing DCM and drug-induced cardiotoxicity ENSG00000096717 ENSG00000062282 PMC7343503__F6 Resveratrol regulating MARCH1 expression ENSG00000171791 ENSG00000168610 PMC3943763__F1 Toll-like receptors in antiviral innate immunity ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC12006078__F4 Mechanisms of action by which acacetin prevents cardiac fibrosis and hypertrophy ENSG00000198793 ENSG00000096717 PMC8580935__F1 Palbociclib as an early-line treatment for Japanese patients with hormone receptor–positive/human epidermal growth factor receptor 2–negative advanced breast cancer: a review of clinical trial and real-world data ENSG00000198793 ENSG00000121067 PMC5572374__F2 Prior knowledge network (PKN) derived from public resources, including interactions connecting nodes which are measured (in blue) or perturbed (stimulated in green and inhibited in red) in the experimental data ENSG00000138798 ENSG00000198793 ENSG00000136997 ENSG00000168610 ENSG00000146648 ENSG00000140443 PMC9684205__F1 Emerging roles of fibroblast growth factor 21 in critical disease ENSG00000105550 PMC12006078__F3 Major signaling pathways of acacetin in protecting against endothelial injury and improving atherosclerosis ENSG00000081181 ENSG00000096717 ENSG00000142082 PMC4094296__F3 Pathogenetic Importance and Therapeutic Implications of NFKB in Lymphoid Malignancies ENSG00000186716 ENSG00000198793 ENSG00000172936 ENSG00000168610 ENSG00000184216 ENSG00000010671 ENSG00000198286 PMC4560668__F1 WNT signaling in adult ovarian folliculogenesis ENSG00000134982 ENSG00000168036 ENSG00000102974 PMC4560668__F2 WNT signaling in adult ovarian folliculogenesis ENSG00000134982 ENSG00000168036 ENSG00000168646 PMC10312928__F5 Protein-protein interaction network and functional enrichment analysis of proteins with acetylation, carbamylation and phosphorylation sites regulated by bacterial lipopolysaccharide ENSG00000182718 ENSG00000160789 ENSG00000099901 ENSG00000105697 ENSG00000178209 ENSG00000177954 ENSG00000108654 ENSG00000161960 ENSG00000009954 ENSG00000164163 ENSG00000101557 ENSG00000167986 ENSG00000130402 ENSG00000055609 PMC3163125__F1 Complement system: the classical complement pathway involves a sequentially acting multistep cascade in which the complement components C1q, C1s, C1r, C4, C2, and C3 play important roles ENSG00000039537 ENSG00000113600 ENSG00000236625 PMC11529338__F5 Bone microenvironment of prostate cancer with bone metastasis ENSG00000102317 ENSG00000168036 ENSG00000164400 ENSG00000165819 PMC12249962__F2 Key metabolic pathways, transcriptomic modulation, and chemotherapeutic and metabolic compounds for prostate cancer treatment PMC12249962__F3 Multi-target promising compounds for prostate cancer (PCa) treatment ENSG00000131473 ENSG00000151726 ENSG00000169710 ENSG00000159399 PMC9318110__F1 New Insights into TRP Ion Channels in Stem Cells ENSG00000144935 ENSG00000137672 ENSG00000072315 ENSG00000077782 ENSG00000138741 PMC9318110__F2 New Insights into TRP Ion Channels in Stem Cells ENSG00000170365 ENSG00000092439 ENSG00000204335 ENSG00000168036 ENSG00000168610 ENSG00000131196 PMC12170767__F4 Process Diagram ENSG00000186191 ENSG00000062485 PMC8197496__F2A Survival-Critical Genes Associated with Copy Number Alterations in Lung Adenocarcinoma ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000111537 ENSG00000197299 ENSG00000123268 ENSG00000139618 PMC2773962__F6 Model of Tbx2 function for the EC formation in the AVC ENSG00000107779 ENSG00000170961 ENSG00000121068 PMC10222578__F5 Networks of interactions between the genes affected by the production of sfRNA in ZIKV infection of human brain organoids ENSG00000112576 ENSG00000110492 ENSG00000139567 ENSG00000143867 ENSG00000163739 ENSG00000159259 ENSG00000122877 ENSG00000151929 ENSG00000118971 ENSG00000112715 ENSG00000124762 ENSG00000285069 ENSG00000109854 ENSG00000009709 ENSG00000139921 ENSG00000163946 ENSG00000117525 ENSG00000174326 ENSG00000168090 ENSG00000291650 ENSG00000129071 ENSG00000172938 ENSG00000063180 ENSG00000026103 ENSG00000138795 ENSG00000124610 ENSG00000197177 ENSG00000077279 ENSG00000198890 ENSG00000074842 ENSG00000173530 ENSG00000128872 ENSG00000065328 ENSG00000152192 ENSG00000069482 ENSG00000173157 ENSG00000172780 ENSG00000150672 ENSG00000135446 ENSG00000041880 ENSG00000112378 ENSG00000144290 PMC1480599__F7 Host-Specific Response to HCV Infection in the Chimeric SCID-beige/Alb-uPA Mouse Model: Role of the Innate Antiviral Immune Response ENSG00000159128 ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000027697 ENSG00000276561 PMC10222578__F6 Interconnection between sfRNA-affected biological processes in ZIKV-infected human brain organoids ENSG00000142627 ENSG00000116729 ENSG00000158234 ENSG00000010327 ENSG00000122877 ENSG00000163736 ENSG00000118971 ENSG00000074842 ENSG00000205683 ENSG00000109854 ENSG00000009709 ENSG00000117525 ENSG00000291527 ENSG00000172780 ENSG00000150672 ENSG00000172938 ENSG00000041880 ENSG00000136146 ENSG00000063180 ENSG00000128602 PMC4086339__F5 Deregulated focal adhesion pathway in NSCLC cell lines ENSG00000118680 ENSG00000130402 ENSG00000099942 ENSG00000136068 PMC11529338__F3 Osteoclast-mediated bone resorption reactivates dormant tumor cells ENSG00000183735 ENSG00000107562 ENSG00000169071 ENSG00000170558 ENSG00000198793 ENSG00000050165 ENSG00000168487 ENSG00000128342 ENSG00000121966 PMC9439914__F2 Biological Mechanism on SIRT1/NLRP3/IL-18 Signaling Pathway of Acupuncture for Treatment of Ischemic Stroke with Center Poststroke Pain ENSG00000111837 ENSG00000084110 ENSG00000124795 ENSG00000004848 PMC10531003__F2 Pathway from Acute Kidney Injury to Chronic Kidney Disease: Molecules Involved in Renal Fibrosis ENSG00000168036 ENSG00000137672 ENSG00000122194 PMC9699238__F8 Fascaplysin Induces Apoptosis and Ferroptosis, and Enhances Anti-PD-1 Immunotherapy in Non-Small Cell Lung Cancer (NSCLC) by Promoting PD-L1 Expression ENSG00000128272 ENSG00000151012 ENSG00000167468 ENSG00000171791 PMC3538603__F8 Neural Stem Cell Death, Survival, and Differentiation in Response to Partial FGF-2 and EGF Deprivation ENSG00000112964 ENSG00000070831 ENSG00000173156 ENSG00000075073 ENSG00000285456 ENSG00000109163 ENSG00000182511 ENSG00000172602 ENSG00000010810 ENSG00000165409 ENSG00000198670 ENSG00000185008 ENSG00000113494 PMC4941544__F2 Overcoming the matched-sample bottleneck: an orthogonal approach to integrate omic data ENSG00000132906 ENSG00000002330 ENSG00000134982 ENSG00000163914 ENSG00000177606 ENSG00000168036 ENSG00000164305 PMC4941544__F3 Overcoming the matched-sample bottleneck: an orthogonal approach to integrate omic data ENSG00000017797 ENSG00000002330 ENSG00000138798 ENSG00000168610 ENSG00000139618 PMC8400927__F10 Cell communication analysis results for integrated choroid plexus and brain parenchyma cell types ENSG00000122012 ENSG00000146469 ENSG00000157005 ENSG00000154146 PMC8834222__F1 Supplementation of Enriched Polyunsaturated Fatty Acids and CLA Cheese on High Fat Diet: Effects on Lipid Metabolism and Fat Profile ENSG00000100422 ENSG00000185813 ENSG00000125538 ENSG00000197977 ENSG00000167676 ENSG00000169710 ENSG00000099194 ENSG00000076555 ENSG00000062282 PMC7892499__F2 Strategies for antagonizing NLRP3 pathway myocarditis-related key inflammatory components ENSG00000162711 ENSG00000143546 ENSG00000167207 ENSG00000163220 PMC6074871__F1 Synopsis of intratumoral cholesterol metabolism ENSG00000057252 ENSG00000130164 ENSG00000073060 ENSG00000113161 ENSG00000104549 ENSG00000169174 ENSG00000198911 PMC5834268__F3 Identification of prefrontal cortex protein alterations in Alzheimer’s disease ENSG00000142192 ENSG00000140564 ENSG00000291603 ENSG00000135218 ENSG00000110680 ENSG00000231179 ENSG00000010671 ENSG00000106927 ENSG00000066468 ENSG00000157368 ENSG00000284816 ENSG00000089692 ENSG00000167996 ENSG00000180616 ENSG00000170477 ENSG00000165471 PMC2673422__F6 Hypoxia-invoked response of the glycolysis gene network ENSG00000130957 ENSG00000262785 ENSG00000074800 ENSG00000067057 ENSG00000170634 ENSG00000119640 ENSG00000164708 ENSG00000136872 ENSG00000159399 ENSG00000152556 PMC7330112__F5 Resistance-associated BTK (C481) mutation and possibilities of its overcoming in ibrutinib-treated CLL patients ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000198793 ENSG00000197943 ENSG00000171791 ENSG00000010671 PMC6205057__F8 The Potential Schematic Diagram of the Effects of CPE on the Beta Cell and Liver Tissue ENSG00000009950 ENSG00000042832 ENSG00000125538 PMC10474200__F4 Interconnectivity between prioritized high confidence transcription factors ENSG00000023445 ENSG00000167601 ENSG00000119403 ENSG00000148926 ENSG00000172543 ENSG00000173039 ENSG00000171462 ENSG00000125347 ENSG00000111348 ENSG00000121966 ENSG00000284984 ENSG00000138378 ENSG00000082175 ENSG00000115457 ENSG00000116688 ENSG00000149273 ENSG00000128342 PMC10474200__F5 Prolactin signaling pathway ENSG00000169291 ENSG00000115415 ENSG00000163914 ENSG00000123609 ENSG00000135605 PMC5179551__F1 Insulin signaling pathway: intracellular insulin signaling is initiated by insulin receptor tyrosine kinase activity leading to the activation of both the PI3K-Akt pathway and the MAPK pathway ENSG00000002330 PMC9111174__F8 Transcriptome Analyses of Chicken Primary Macrophages Infected With Attenuated Salmonella Typhimurium Mutants ENSG00000174125 ENSG00000150782 ENSG00000125538 ENSG00000172936 ENSG00000106100 ENSG00000276561 ENSG00000164342 PMC8277916__F4 Computational Drug Repurposing for Alzheimer’s Disease Using Risk Genes From GWAS and Single-Cell RNA Sequencing Studies ENSG00000125538 PMC9128211__F1 Biology of YAP in programmed cell death ENSG00000087095 ENSG00000156299 ENSG00000291971 ENSG00000136997 ENSG00000020633 ENSG00000104447 ENSG00000277276 PMC8277916__F5 Computational Drug Repurposing for Alzheimer’s Disease Using Risk Genes From GWAS and Single-Cell RNA Sequencing Studies ENSG00000178573 ENSG00000291761 ENSG00000079999 PMC10572622__F3 Representation of part of phenylpropanoids and oleuropein biosynthetic pathway in olive fruits PMC10865529__F5 Phenolic metabolic pathways and associated network diagrams ENSG00000179934 ENSG00000121807 ENSG00000084774 PMC6294171__F2 Canonical and non-canonical inflammasome signaling pathways.Notes: The figure describes both the canonical and non-canonical signaling pathways involved in the activation of different inflammasome components including NLRP1, NLRP3, NLRC4, and AIM2 ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000091592 ENSG00000091106 PMC7460640__F3 Sex-related signaling pathways in aortic valve fibro-calcification ENSG00000115415 ENSG00000111341 PMC3665348__F8 Summary of differential metabolism of procainamide in humans and mice ENSG00000140465 PMC7330112__F1 B-cell receptor (BCR) signaling pathway and BCR inhibitors ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000198793 ENSG00000197943 ENSG00000171791 ENSG00000010671 PMC4491511__F1 In response to diverse biological stressors, macrophage migration inhibitory factor (MIF) is secreted from preformed intracytoplasmic pools ENSG00000019582 ENSG00000026508 PMC8450361__F1 Caloric Restriction May Help Delay the Onset of Frailty and Support Frailty Management ENSG00000198793 ENSG00000096717 PMC9581181__F2 Ion channels as a therapeutic target for renal fibrosis ENSG00000162711 ENSG00000092439 ENSG00000293604 ENSG00000198793 ENSG00000137672 ENSG00000196689 PMC2432084__F9 p27Kip1 nuclear localization and cyclin-dependent kinase inhibitory activity are regulated by glycogen synthase kinase-3 in human colon cancer cells ENSG00000145604 ENSG00000123374 PMC3083340__F3 Top network affected by MAA ENSG00000132906 ENSG00000002330 ENSG00000085117 ENSG00000140575 ENSG00000170558 ENSG00000150093 ENSG00000091409 ENSG00000168610 ENSG00000164305 ENSG00000053747 ENSG00000064012 ENSG00000139687 ENSG00000140443 PMC6008335__F1 Synthetic biology-inspired genetic circuits for caffeine-induced gene expression ENSG00000131724 ENSG00000168610 PMC4608393__F1 Schematic view of the LPS-mediated NFKB pathway ENSG00000172936 ENSG00000150455 ENSG00000175104 PMC4990292__F1 Colorectal tumorigenesis in proximal/whole-colon and distal serrated polyposis ENSG00000157764 ENSG00000134982 ENSG00000170430 PMC3731936__F5 Sequestration-induced loss of protein C receptors links coagulation, inflammation, and endothelial permeability ENSG00000110799 ENSG00000134982 ENSG00000173599 ENSG00000100985 PMC6038710__F3 Hypothetical model for the role of lncRNAs in rheumatoid diseases ENSG00000132906 ENSG00000169245 ENSG00000138378 ENSG00000164430 ENSG00000138755 ENSG00000170373 ENSG00000168610 ENSG00000164305 PMC11922731__F8 This graphic illustrating the role of the CXCL2/CXCR2/Jun signaling pathway in microglia-neuron crosstalk in SAE ENSG00000081041 ENSG00000177606 ENSG00000072274 ENSG00000073756 PMC3983570__F3 Tau Acts as a Mediator for Alzheimer's Disease-Related Synaptic Deficits ENSG00000010810 PMC3787041__F5 Live Attenuated Rev-Independent Nef¯SIV Enhances Acquisition of Heterologous SIVsmE660 in Acutely Vaccinated Rhesus Macaques ENSG00000019991 ENSG00000188554 ENSG00000224320 ENSG00000173575 ENSG00000183625 ENSG00000138755 ENSG00000277236 ENSG00000147896 PMC3176897__F1 Summary of fatty acid and glucose metabolism ENSG00000135218 PMC1456973__F6 Aspartate and aspartate transport in the pathway of prostate citrate production ENSG00000122966 ENSG00000172005 ENSG00000062485 PMC8262608__F1 Interleukin-1- Receptor Kinase 4 Inhibition: Achieving Immunomodulatory Synergy to Mitigate the Impact of COVID-19 ENSG00000174125 ENSG00000137033 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC8220219__F1 Hippo, TGFB/SMAD, Wnt/Beta-Catenin, JAK/STAT, and NOTCH by Long Non-Coding RNAs in Pancreatic Cancer ENSG00000150457 ENSG00000131023 PMC9138541__F9 CAST as a Potential Oncogene, Identified by Machine Search, in Gastric Cancer Infiltrated with Macrophages and Associated with Lgr5 ENSG00000154342 ENSG00000163251 ENSG00000162441 ENSG00000134245 ENSG00000188763 ENSG00000104332 ENSG00000177283 ENSG00000277641 ENSG00000155760 ENSG00000125084 ENSG00000157240 PMC8220219__F2 Hippo, TGFB/SMAD, Wnt/Beta-Catenin, JAK/STAT, and NOTCH by Long Non-Coding RNAs in Pancreatic Cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC4103865__F2 Integrating Genomics and Proteomics Data to Predict Drug Effects Using Binary Linear Programming ENSG00000171105 ENSG00000002330 ENSG00000167658 ENSG00000026103 PMC8220219__F3 Hippo, TGFB/SMAD, Wnt/Beta-Catenin, JAK/STAT, and NOTCH by Long Non-Coding RNAs in Pancreatic Cancer ENSG00000066735 ENSG00000167772 ENSG00000196363 PMC7512049__F8 Key network of “drug-component-target-biological process- signaling pathway” (P < 0.05) ENSG00000180210 ENSG00000171049 ENSG00000168398 ENSG00000005381 ENSG00000168610 ENSG00000146648 ENSG00000164305 PMC8220219__F4 Hippo, TGFB/SMAD, Wnt/Beta-Catenin, JAK/STAT, and NOTCH by Long Non-Coding RNAs in Pancreatic Cancer ENSG00000162772 ENSG00000149480 PMC4248707__F2 mRNA decay pathways in the cytoplasm ENSG00000135473 ENSG00000114127 ENSG00000172795 PMC11897526__F1 Natural products for the treatment of ulcerative colitis: focus on the JAK/STAT pathway ENSG00000105397 ENSG00000142224 PMC11897526__F2 Natural products for the treatment of ulcerative colitis: focus on the JAK/STAT pathway ENSG00000138378 ENSG00000105397 ENSG00000168610 PMC11868397__F7 Pattern of USP35 negatively regulates the MAVS signaling pathway to attenuate type I interferon production ENSG00000118369 ENSG00000183735 ENSG00000088888 PMC6188467__F1 RNA-seq analysis revealed that LECs exhibit a highly perturbed cytokine–cytokine receptor pathway at 24 hours PCS ENSG00000124102 ENSG00000104899 ENSG00000139269 ENSG00000163083 ENSG00000174564 ENSG00000122025 ENSG00000226275 ENSG00000145839 ENSG00000135960 ENSG00000117400 ENSG00000128052 ENSG00000163734 ENSG00000113520 ENSG00000147896 ENSG00000037280 ENSG00000026103 ENSG00000113494 ENSG00000016402 PMC7653775__F7 An overview of homocysteine metabolism and the transsulfuration pathway ENSG00000116761 ENSG00000133027 PMC9472369__F4 Effect of Nrf2 deletion on the proteomic signature in a human colorectal cancer cell line ENSG00000170899 ENSG00000184470 ENSG00000183048 ENSG00000008394 ENSG00000085871 ENSG00000176153 ENSG00000164294 ENSG00000168765 PMC5343002__F3 Adipose tissue pathways regulated by sirtuins (SIRTs) and poly(ADP-ribose) polymerases (PARPs) based on current literature in mouse models, adipocyte cell lines and human studies ENSG00000143799 ENSG00000187531 ENSG00000105835 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000089163 ENSG00000283100 PMC3461631__F2 Signaling cascades mediated by plexin-A and plexin-B, and their crosstalk with oncogenic pathways in gliomas ENSG00000010810 PMC5343002__F2 Cellular NAD+ biosynthesis and consumption processes ENSG00000105835 ENSG00000278488 ENSG00000157064 ENSG00000173614 PMC3203685__F1 Summary of the Proceedings from the 10th Annual Meeting of Molecularly Targeted Therapy in NSCLC ENSG00000164327 PMC3436276__F7 Model illustrates proposed two pathways of regulation of S100A4 mediated by HBXIP ENSG00000138378 ENSG00000196154 PMC4810272__F6 3Cpro from different picornaviruses suppress the immune response ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000114030 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC7608146__F8 Wnt signaling and Loxl2 promote aggressive osteosarcoma ENSG00000108839 ENSG00000169554 ENSG00000116729 ENSG00000188064 ENSG00000146648 PMC10147314__F5 NAE inhibitor MLN4924 has utility in the treatment of lung cancer ENSG00000096395 ENSG00000198793 ENSG00000184182 PMC8867675__F2 Integration of liquid biopsy and pharmacogenomics for precision therapy of EGFR mutant and resistant lung cancers ENSG00000019991 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC10147314__F3 Several signaling pathways are closely related to NEDD8 ENSG00000166794 ENSG00000198793 PMC10147314__F4 Several signaling pathways are closely related to NEDD8 ENSG00000134086 ENSG00000044090 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC3535349__F1 Iron homeostasis in absorptive enterocytes, macrophages, erythroblasts, and hepatocytes and its routes of circulation in the organism ENSG00000010704 ENSG00000182511 ENSG00000089472 ENSG00000106327 PMC10147314__F2 NEDD8 regulates the ubiquitin-proteasome degradation pathways related to CRL and MDM2, and it realizes the regulation of proteins by promoting the NFKB, PI3K/AKT/mTOR, Hippo-YAP and receptor tyrosine kinase signaling pathways ENSG00000134086 ENSG00000198793 ENSG00000285246 ENSG00000146648 PMC10854597__F8 FAK signaling in FLNC cardiomyopathy ENSG00000081913 ENSG00000134853 PMC3535349__F2 Iron transport across the placenta (syncytiotrophoblasts) ENSG00000010704 ENSG00000182511 ENSG00000106327 ENSG00000115107 PMC2934865__F2 Hypothetical model for SUMO regulation in NFKB pathway ENSG00000102871 ENSG00000172936 ENSG00000168040 ENSG00000175104 PMC3501082__F7 A model to depict Tollip cooperating with Smad7 to mediate degradation of the TGFB receptor complex ENSG00000136535 ENSG00000166278 PMC8312177__F1 Analysis of the association and predictive value of hyperhomocysteinaemia for obstructive coronary artery disease PMC8773597__F2 Nrf2-Related Therapeutic Effects of Curcumin in Different Disorders ENSG00000162711 ENSG00000198793 ENSG00000171791 ENSG00000079999 PMC10876703__F7 TEAD1 promotes the fibroblast-to-myofibroblast transition during TAC or Ang-II-induced pathological cardiac remodelling through the Wnt signalling pathway ENSG00000162552 ENSG00000141867 ENSG00000168036 PMC9312505__F12 Alcohol and HIV-Derived Hepatocyte Apoptotic Bodies Induce Hepatic Stellate Cell Activation ENSG00000168610 PMC3655322__F4 Diagram showing some of the downstream elements of the proposed Hippo pathway ENSG00000135446 PMC11048214__F5 IPA canonical pathway analysis in genes containing prioritised variants ENSG00000110711 ENSG00000142192 ENSG00000166855 ENSG00000120915 ENSG00000137992 ENSG00000114054 ENSG00000109089 ENSG00000172005 ENSG00000110435 ENSG00000115419 PMC10970167__F1 The protein interactome of PDE4A, B, C and D with their interconnecting protein neighbors ENSG00000110711 ENSG00000123240 ENSG00000291971 ENSG00000138794 ENSG00000126804 ENSG00000121058 ENSG00000005102 ENSG00000106511 ENSG00000063515 ENSG00000141480 ENSG00000010810 ENSG00000132646 ENSG00000177606 ENSG00000005893 ENSG00000056558 ENSG00000172238 PMC6035197__F2 Signaling for apoptosis and carcinogenesis pathway differentiation ENSG00000134982 ENSG00000138794 ENSG00000198793 ENSG00000136997 ENSG00000164305 PMC3655322__F3 Diagram showing some of the upstream elements of the proposed Hippo pathway ENSG00000167601 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC3895871__F1 TWEAK/Fn14 Signaling ENSG00000104856 ENSG00000082512 ENSG00000056558 ENSG00000131323 ENSG00000127191 PMC7108750__F3 Signaling pathways coordinating the hepatic regenerative response ENSG00000019991 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000133067 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000150457 ENSG00000131023 ENSG00000186575 ENSG00000108375 ENSG00000154309 ENSG00000164690 ENSG00000128602 ENSG00000146648 PMC8483493__F8 Proposed the mechanism within the hypothalamic nuclei proopiomelanocortin (POMC) neurons that leptin signaling may contribute to the high sympathetic nerve activity (SNA) and increased blood pressure observed in the HFD obese rats ENSG00000115138 ENSG00000096717 ENSG00000168610 PMC8570864__F5 Unveiling the Mechanism of Principal Drugs of Lianpu Drink on Chronic Gastritis by Network Pharmacology ENSG00000182511 ENSG00000168040 ENSG00000237834 PMC5357279__F2 Intracellular trafficking path for SORLA ENSG00000175115 ENSG00000143376 ENSG00000103365 ENSG00000100083 PMC7793864__F1 Cartoon summarizes intracellular pathways used by cancer cells to support increased citrate synthesis in mitochondria ENSG00000131473 ENSG00000092621 ENSG00000173599 ENSG00000135069 PMC3414447__F6 n-Butyl Benzyl Phthalate Promotes Breast Cancer Progression by Inducing Expression of Lymphoid Enhancer Factor 1 ENSG00000142192 ENSG00000105397 ENSG00000241186 ENSG00000106070 ENSG00000102970 ENSG00000175899 ENSG00000143322 ENSG00000136160 ENSG00000196628 PMC3412960__F4 Scheme of the Rho signaling canonical pathway identified in Ingenuity Pathway Analysis of the proteins with altered expression in both KO cell lines ENSG00000114993 ENSG00000132694 ENSG00000284816 ENSG00000173599 ENSG00000116584 ENSG00000198670 ENSG00000111348 ENSG00000092820 ENSG00000140443 PMC8673831__F4 SNPs in miRNAs and Target Sequences: Role in Cancer and Diabetes ENSG00000145384 PMC12080399__F11 Mechanistic diagram illustrating the detrimental effects of TRMT10C in the nucleus under hypoxic conditions via m1A modification ENSG00000162711 ENSG00000198492 ENSG00000160703 ENSG00000174173 ENSG00000186432 ENSG00000102125 PMC8673831__F3 SNPs in miRNAs and Target Sequences: Role in Cancer and Diabetes ENSG00000171105 ENSG00000101255 ENSG00000169047 ENSG00000198793 PMC7051141__F1 New control of the senescence barrier in breast cancer ENSG00000104856 ENSG00000172216 ENSG00000130669 PMC7308494__F1 RIPK3 and TGFB1 ENSG00000162711 ENSG00000137275 ENSG00000125538 ENSG00000136869 ENSG00000168404 ENSG00000285379 PMC4900219__F10 Proposed mechanism of DCLF/cytokine-induced cytotoxic synergy ENSG00000115415 PMC4663793__F3 Transcriptome analysis of human OXR1 depleted cells reveals its role in regulating the p53 signaling pathway ENSG00000132906 ENSG00000105327 ENSG00000085117 ENSG00000196470 ENSG00000198892 ENSG00000164305 ENSG00000149311 ENSG00000175054 ENSG00000172667 ENSG00000136997 ENSG00000123374 ENSG00000112378 ENSG00000177519 ENSG00000120868 PMC10888664__F2 Evolution of CRC ENSG00000157764 ENSG00000134982 ENSG00000168036 PMC11338244__F4 Methylation of the PI3K/AKT/mTOR signaling pathway on tamoxifen ENSG00000162433 ENSG00000164093 ENSG00000162772 ENSG00000177108 ENSG00000165819 ENSG00000130513 PMC3516782__F5 Metabolic pathway of mannan in R ENSG00000132329 ENSG00000131477 PMC11338244__F2 Tamoxifen resistance ENSG00000198793 PMC1173149__F10 TAp63Alpha-induced apoptosis ENSG00000120868 ENSG00000171791 PMC5623058__F5 Lipid metabolism regulatory network proposed for the breast of female chickens at hatching, based on significant DEGs and KEGG pathway analysis ENSG00000164690 ENSG00000132170 PMC6851151__F1 Current translational potential and underlying molecular mechanisms of necroptosis ENSG00000168404 ENSG00000285379 PMC5874051__F3 Gene cloning of a neutral ceramidase from the sphingolipid metabolic pathway based on transcriptome analysis of Amorphophallus muelleri ENSG00000100422 ENSG00000170266 ENSG00000188611 ENSG00000070610 PMC5734045__F2 Interactions between the Wood-Ljungdahl pathway, the Embden-Meyerhof-Parnas glycolytic pathway, and the mevalonic acid pathway for the synthesis of isoprene ENSG00000110921 ENSG00000167508 PMC6046465__F8 The “cross-talk” between purinergic receptors during the uridine triphosphate (UTP)-mediated control of Leishmania amazonensis infection ENSG00000110218 PMC5983636__F1 Mammalian target of rapamycin (mTOR) signaling pathway ENSG00000177169 ENSG00000198793 ENSG00000155792 ENSG00000164327 PMC4994014__F1 IL-21 signaling pathway ENSG00000186716 ENSG00000196092 ENSG00000105639 PMC4994014__F2 B-cell activation and differentiation ENSG00000186716 ENSG00000010671 PMC6959353__F1 Example of atom mappings of the 13C-labeling experiment used for isotopomer analysis ENSG00000122966 ENSG00000173599 ENSG00000172005 ENSG00000062485 PMC4994014__F3 Immunoglobulin (Ig) production ENSG00000186716 ENSG00000105639 ENSG00000010671 PMC9258714__F6 SQLE facilitates the pancreatic cancer progression via the lncRNA‐TTN‐AS1/miR‐133b/SQLE axis ENSG00000132646 ENSG00000104549 ENSG00000123374 PMC4994014__F5 B-cell apoptosis ENSG00000115415 ENSG00000105639 ENSG00000168610 PMC7431799__F10 Model showing how PRRSV utilizes viral apoptotic mimicry and TIM-induced macropinocytosis as an alternative pathway to infect host cells ENSG00000177575 ENSG00000070831 ENSG00000149269 PMC10341168__F9 Ginsenoside Rh4 Improves Hepatic Lipid Metabolism and Inflammation in a Model of NAFLD by Targeting the Gut Liver Axis and Modulating the FXR Signaling Pathway ENSG00000042832 ENSG00000180432 ENSG00000169710 PMC9139581__F5 Integrated Analysis of Cancer Tissue and Vitreous Humor from Retinoblastoma Eyes Reveals Unique Tumor-Specific Metabolic and Cellular Pathways in Advanced and Non-Advanced Tumors ENSG00000150782 ENSG00000276559 ENSG00000196591 ENSG00000197375 ENSG00000134595 ENSG00000281857 ENSG00000152556 PMC7307098__F8 Working model of the innate immune response to papillomavirus infection of the female lower genital tract ENSG00000115415 ENSG00000172936 ENSG00000115009 ENSG00000112486 PMC2769196__F4 Acromegaly pathogenesis and treatment ENSG00000291972 ENSG00000135446 ENSG00000105810 ENSG00000087460 ENSG00000064835 PMC5206990__F3 Rationale for combination therapy in lymphoma ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000198793 ENSG00000010671 PMC7471511__F11 Dichotomy in gene regulatory associations during the activated B-cell to plasmablast transition ENSG00000156127 ENSG00000186716 ENSG00000137265 ENSG00000269404 ENSG00000100219 ENSG00000102974 PMC8065335__F5 Putative mechanisms for CVL218 as a PARP1 inhibitor to combat the COVID-19 disease, derived based on the data present in this study and the known antiviral activities of PARP1 inhibitors previously reported in the literature ENSG00000143799 ENSG00000125538 PMC6955653__F3 Role of lncRNAs and circRNAs in osteosarcoma ENSG00000067900 ENSG00000107175 ENSG00000213523 PMC3112285__F2 Pathway Crosstalk PMC3117038__F1 The roles of CARM1 and coactivator methylation in DNA damage signaling pathway ENSG00000149311 ENSG00000012048 ENSG00000142453 PMC8004207__F17 Schematic diagram showing the effect of prenatal exposure to VPA on the pathological changes in the brains of young-adult male offspring PMC9664406__F4 Mitochondrion-targeted RNA therapies as a potential treatment strategy for mitochondrial diseases ENSG00000132463 PMC9755959__F8 MiR-378a-3p acts as a tumor suppressor in gastric cancer via directly targeting RAB31 and inhibiting the Hedgehog pathway proteins GLI1/2 ENSG00000168461 ENSG00000164690 ENSG00000128602 PMC4021516__F7 Wild-type p53 (WT-p53) and mutant p53 differentially regulate Nox4 expression in both TGF-Beta-dependent and independent mechanisms ENSG00000086991 PMC3914472__F1 Metabolic pathway of the glycine cleavage enzyme system and the synthesis of its lipoate cofactor ENSG00000121897 ENSG00000144182 ENSG00000182511 ENSG00000291958 ENSG00000175536 ENSG00000100209 ENSG00000145020 ENSG00000136003 ENSG00000178445 ENSG00000169599 ENSG00000026103 PMC2689134__F4 Pathogenesis of holoprosencephaly ENSG00000170365 ENSG00000180447 ENSG00000160973 ENSG00000183691 ENSG00000156574 ENSG00000164690 ENSG00000128602 ENSG00000204217 ENSG00000291597 PMC4563671__F8 Death-associated protein kinase 1 promotes growth of p53-mutant cancers PMC2788597__F3 Metabolic pathway of pitavastatin ENSG00000171234 PMC6247470__F3 Paeonol protects against atherogenesis ENSG00000135218 ENSG00000198793 ENSG00000113161 ENSG00000172936 ENSG00000026103 PMC8995882__F2 Construction Immune Related Feed-Forward Loop Network Reveals Angiotensin II Receptor Blocker as Potential Neuroprotective Drug for Ischemic Stroke ENSG00000163464 ENSG00000134460 ENSG00000107562 ENSG00000139567 ENSG00000183625 ENSG00000121807 ENSG00000121966 ENSG00000163702 ENSG00000100385 ENSG00000123496 ENSG00000282604 ENSG00000169429 ENSG00000113520 ENSG00000131724 ENSG00000115594 ENSG00000115008 ENSG00000147168 ENSG00000115590 ENSG00000110324 ENSG00000177663 ENSG00000277943 ENSG00000186810 ENSG00000112116 ENSG00000108691 ENSG00000108700 ENSG00000243646 ENSG00000112115 PMC6016866__F5 The effect of the IR on the expression of the IGF-1Ec isoform ENSG00000112964 ENSG00000168610 PMC8678298__F1 Renal and Intestinal Urate Physiology ENSG00000146039 ENSG00000137204 ENSG00000172005 ENSG00000118777 ENSG00000109667 PMC9621223__F2 Short Sleep Duration and Erectile Dysfunction: A Review of the Literature ENSG00000145321 PMC5759178__F6 Schematic model for EGFR-PI3K/AKT signaling activation induced by Notch1C1133Y mutation ENSG00000148400 ENSG00000140287 ENSG00000146648 PMC10940489__F7 STAT3 influences cardiac fibrosis through multiple pathways ENSG00000168610 PMC8278519__F2 Specialized Pro-Resolving Mediators Mitigate Cancer-Related Inflammation: Role of Tumor-Associated Macrophages and Therapeutic Opportunities ENSG00000111537 ENSG00000113520 ENSG00000128342 PMC4626583__F3 Function of bacterial actin nucleators during infection ENSG00000173163 ENSG00000138398 ENSG00000160691 PMC3425429__F1 Working model depicting some of the multiple signaling pathways that have been reported to modulate cell-cycle activation and/or proliferation in rodent Beta-cells ENSG00000019991 ENSG00000139287 ENSG00000129167 ENSG00000150907 ENSG00000169047 ENSG00000113494 PMC4179136__F5 Perturbation of MAPK signaling pathway at 24 h after MPP+ treatment ENSG00000087095 ENSG00000172680 ENSG00000157764 ENSG00000108861 ENSG00000130522 ENSG00000138798 ENSG00000213341 ENSG00000130159 ENSG00000127191 ENSG00000164305 ENSG00000132676 ENSG00000197461 ENSG00000128272 ENSG00000178573 ENSG00000177606 ENSG00000136997 ENSG00000134853 ENSG00000126458 ENSG00000026103 PMC4179136__F6 Perturbation of ER protein processing pathway at 24 h after MPP+ treatment ENSG00000072849 ENSG00000103266 ENSG00000138674 ENSG00000137992 ENSG00000165280 ENSG00000127022 ENSG00000198168 ENSG00000137055 ENSG00000089597 ENSG00000185825 ENSG00000160202 PMC3935308__F2 High-confidence reaction map of the TSLP signaling pathway ENSG00000033327 ENSG00000100906 ENSG00000291971 ENSG00000114737 ENSG00000132478 ENSG00000145777 ENSG00000292363 ENSG00000010671 ENSG00000138378 ENSG00000182511 ENSG00000077150 ENSG00000136997 ENSG00000135605 PMC11394960__F10 Contribution of miRs/target genes involved in the innate immune and inflammatory response pathway in the spleen in Lagovirus europaeus infection ENSG00000162711 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC4179136__F4 Perturbation of the MAPK signaling pathway at 9 h after MPP+ treatment ENSG00000087095 ENSG00000172680 ENSG00000157764 ENSG00000138798 ENSG00000115904 ENSG00000213341 ENSG00000130159 ENSG00000164305 ENSG00000090316 ENSG00000170458 ENSG00000143507 ENSG00000177606 ENSG00000136997 ENSG00000146648 ENSG00000196712 ENSG00000133818 ENSG00000026103 PMC8011850__F8 Model depicting the pathway stimulated by TNFA to increase venous endothelial permeability ENSG00000291971 ENSG00000110218 PMC3445701__F7 Alzheimer’s Disease pathway from KEGG ENSG00000132906 ENSG00000291983 ENSG00000142192 ENSG00000002330 ENSG00000120868 ENSG00000168040 ENSG00000119912 ENSG00000164305 PMC4330251__F3 Wnt signaling pathway from Kyoto Encyclopedia of Genes and Genomes (KEGG) (SFRP genes are in red box) ENSG00000087095 ENSG00000095739 ENSG00000134982 ENSG00000167941 ENSG00000113558 ENSG00000214253 PMC6480215__F1 Regulation of osteoblast proliferation and differentiation by transcription factors ENSG00000291837 ENSG00000168036 ENSG00000163501 PMC6480215__F2 Calvarial bone development and suture closure ENSG00000066468 ENSG00000041982 ENSG00000029559 ENSG00000118785 ENSG00000149294 ENSG00000169884 ENSG00000108821 ENSG00000163501 ENSG00000125084 PMC3334867__F5 Inborn Errors of Human JAKs and STATs ENSG00000111537 ENSG00000099985 ENSG00000242689 ENSG00000115415 ENSG00000128342 ENSG00000168610 ENSG00000105205 PMC6848778__F9 KEGG analysis of carbonylated lysosomal proteins in human end-stage PSC ENSG00000167074 ENSG00000119912 ENSG00000127948 PMC11974029__F1 Mechanisms through which berberine treats breast cancer involve modulation of the XRCC1 enzyme in BER ENSG00000132646 PMC11974029__F2 Mechanisms by which capsaicin treat NSCLC involve modulation of the ERCC1 enzyme in the NER pathway ENSG00000012061 ENSG00000134574 ENSG00000132646 ENSG00000167986 ENSG00000196689 PMC2954851__F2 Protein serine/threonine phosphatases in the DNA damage response pathway ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000113456 PMC4790586__F5 Signaling cascades through Twist and their roles in carcinogenesis ENSG00000176692 ENSG00000170558 ENSG00000272398 ENSG00000168610 PMC11974029__F3 Apigenin holds promise in the treatment of ischemic stroke by modulating RAD51 and BRCA1 during HRR as well as Ku70/80 in NHEJ ENSG00000012048 ENSG00000198793 ENSG00000051180 PMC5740024__F1 pH Dependent general base catalyzed activation rather than isocyanate liberation may explain the superior anticancer efficacy of laromustine compared to related 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)hydrazine prodrugs ENSG00000145321 ENSG00000170430 PMC11974029__F5 Retigeric acid B effectively treats prostate cancer by modulating the MSH2 and MSH6 enzymes involved in MMR ENSG00000149311 ENSG00000012048 ENSG00000051180 ENSG00000095002 PMC5139832__F3 Differentially expressed genes between young and aged tibiae are significantly enriched for ECM-receptor interactions, TCA cycle and cell cycle pathway components ENSG00000073578 ENSG00000205250 ENSG00000163541 ENSG00000105953 ENSG00000091651 ENSG00000101224 ENSG00000276876 ENSG00000094804 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000146701 ENSG00000062485 PMC11945191__F1 The host type I interferon signaling pathway by bacteria ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000167207 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000106100 ENSG00000164342 PMC6035044__F2 Prolactin Regulation of the Prostate Gland: A Female Player in a Male Game PMC5504267__F2 Reactions involving ROS, antioxidant systems and energy metabolism ENSG00000112992 ENSG00000023909 PMC3504728__F7 Speculative model of macrophage alternative activation regulation by estrogen PMC7670425__F3 Critical roles of FAM134B in ER-phagy and diseases ENSG00000127863 PMC6060635__F1 Expanding complement therapeutics for the treatment of paroxysmal nocturnal hemoglobinuria ENSG00000113600 ENSG00000182326 PMC4681751__F1 Biological interaction network revealed by Ingenuity Pathway Analysis ENSG00000128016 ENSG00000186395 ENSG00000185022 ENSG00000100979 ENSG00000138311 ENSG00000158874 ENSG00000055955 ENSG00000115718 ENSG00000086730 ENSG00000283082 ENSG00000236625 ENSG00000163631 PMC7826375__F6 The interplay between ATRX and RECQ5 to regulate distinct subpathways of HR ENSG00000178295 ENSG00000132646 ENSG00000197299 PMC8836457__F1 Sclerostin in Bone Diseases ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC7957553__F3 ROS-dependent transduction signaling ENSG00000181019 ENSG00000177606 ENSG00000105227 ENSG00000079999 PMC2656226__F6 Mitochondrial regulation of the apoptotic pathway is altered in disease and modulated by sirolimus treatment ENSG00000133895 ENSG00000002330 ENSG00000100906 ENSG00000159388 ENSG00000258643 ENSG00000084774 ENSG00000115317 PMC2656226__F9 Complement pathway altered in disease ENSG00000009724 ENSG00000203710 ENSG00000244731 ENSG00000117322 ENSG00000062485 ENSG00000236625 PMC6948348__F4 The integrated NSCLC pathway for compound Liuju formula ENSG00000177455 ENSG00000019991 ENSG00000087245 ENSG00000065833 ENSG00000102871 ENSG00000186716 ENSG00000125538 ENSG00000173083 ENSG00000100985 ENSG00000112715 PMC5553087__F1 Toll-like receptor (TLR) stimulation, signaling, and immunological outcomes ENSG00000174125 ENSG00000183735 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC3860870__F1 Apoptosis by HPV early proteins: A number of the interactions of viral oncoproteins with cellular proteins and their effects on apoptosis ENSG00000168040 ENSG00000026103 PMC8329414__F2 Annexin A3, a Calcium-Dependent Phospholipid-Binding Protein: Implication in Cancer ENSG00000138772 ENSG00000198793 PMC8581873__F2 Expression and crucial role of long non-coding RNA FGD5-AS1 in human cancers ENSG00000108654 PMC3854132__F1 Systems Modeling of Anti-apoptotic Pathways in Prostate Cancer: Psychological Stress Triggers a Synergism Pattern Switch in Drug Combination Therapy ENSG00000002330 ENSG00000146469 ENSG00000138798 ENSG00000146648 PMC3652637__F11 Neural Regulation of Lacrimal Gland Secretory Processes: Relevance in Dry Eye Diseases ENSG00000138798 ENSG00000145321 PMC7178030__F1 Timeline of genes involved in gonadal development ENSG00000162552 ENSG00000104899 ENSG00000143355 ENSG00000150990 ENSG00000138795 ENSG00000285109 ENSG00000168036 ENSG00000134595 ENSG00000102678 ENSG00000066468 ENSG00000170370 ENSG00000125398 ENSG00000005513 ENSG00000183579 ENSG00000139549 PMC6139073__F1 Wingless/integrated (Wnt) signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC8187637__F2 Canonical stress granule assembly pathway ENSG00000122566 ENSG00000144895 ENSG00000182944 ENSG00000177733 PMC2724271__F4 Metabolic map of HIF-target genes ENSG00000104812 ENSG00000149930 ENSG00000181163 ENSG00000066926 ENSG00000072274 ENSG00000163064 ENSG00000149308 ENSG00000112715 ENSG00000171345 ENSG00000121966 ENSG00000129219 ENSG00000186575 ENSG00000074800 ENSG00000138764 ENSG00000076928 ENSG00000011422 ENSG00000168214 ENSG00000115457 ENSG00000112394 ENSG00000119912 ENSG00000087245 ENSG00000175606 ENSG00000073756 ENSG00000197461 ENSG00000292348 ENSG00000105364 ENSG00000283018 ENSG00000155287 ENSG00000164362 ENSG00000159352 ENSG00000136003 ENSG00000159399 ENSG00000084774 PMC3196743__F2 The Contribution of Vitamin A to Autocrine Regulation of Fat Depots ENSG00000245848 ENSG00000145321 PMC1421310__F1 High-Throughput Drug Screening of the DPC4 Tumor-Suppressor Pathway in Human Pancreatic Cancer Cells ENSG00000170365 PMC3133232__F8 Schematic model of Nrf2 regulation by Keap1 ENSG00000178573 ENSG00000100387 ENSG00000079999 PMC5046039__F2 Molecular regulation of MSCs during bone formation ENSG00000152266 ENSG00000134982 ENSG00000138798 ENSG00000168036 ENSG00000128602 ENSG00000163501 ENSG00000204217 PMC2824740__F5 Strain-induced quantitative mRNA-expression analysis of PDL cells related to MAP-kinase signalling and cell cycle, ECM and integrins, and growth factor pathways ENSG00000262406 ENSG00000150782 ENSG00000124882 ENSG00000113070 ENSG00000112715 ENSG00000102678 ENSG00000187955 ENSG00000150630 PMC3484412__F2 Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway ENSG00000198793 PMC2990406__F8 A previously unknown miR-290–dependent pathway controls DNA methylation via Rbl2 and affects telomere integrity and telomere-length homeostasis ENSG00000103479 ENSG00000088305 PMC7878609__F3 Pre-existing Cell States Control Heterogeneity of Both EGFR and CXCR4 Signaling ENSG00000107562 ENSG00000138798 ENSG00000146648 ENSG00000121966 PMC11621799__F4 Pathway activation in ACO and COPD identified through KEGGpathway enrichmentanalysis ENSG00000188486 ENSG00000162711 ENSG00000124256 ENSG00000137033 ENSG00000102871 ENSG00000198793 ENSG00000072274 ENSG00000168040 ENSG00000168610 ENSG00000134086 ENSG00000100387 ENSG00000136869 ENSG00000083799 ENSG00000168404 ENSG00000143258 ENSG00000127948 ENSG00000026103 ENSG00000164342 PMC7397096__F7 Myelin basic protein fragment induces sexually dimorphic transcriptome signatures of neuropathic pain in mice ENSG00000171720 ENSG00000110395 ENSG00000082175 ENSG00000173599 ENSG00000142453 ENSG00000113520 ENSG00000108654 ENSG00000136869 ENSG00000141456 PMC2504032__F8 Mechanism for the Inhibition of Neural Progenitor Cell Proliferation by Cocaine ENSG00000128272 ENSG00000144895 ENSG00000123374 ENSG00000145386 PMC9388649__F7 TMEM16E affecting bone metabolism through intracellular Ca2+ signal transmission ENSG00000152266 ENSG00000168036 ENSG00000131196 PMC7660084__F1 Summary of signaling pathways involved in the differentiation of pluripotent cells into corneal epithelial cells ENSG00000170365 ENSG00000134982 ENSG00000156574 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000155760 PMC548501__F4 Taxotere and Furtulon on cell cycle, apoptosis, and other pathway related gene expression analyzed and visualized by GenMAPP software integrated with cDNA microarray data ENSG00000167074 ENSG00000099860 ENSG00000118707 ENSG00000116717 ENSG00000171791 ENSG00000136807 ENSG00000012048 ENSG00000163435 ENSG00000135446 ENSG00000132646 ENSG00000123374 ENSG00000004897 ENSG00000105810 ENSG00000116649 PMC8847901__F1 Autophagy and skin wound healing ENSG00000152348 ENSG00000123395 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC8929358__F4 Metabolism and disposition of opicapone in the rat and metabolic enzymes phenotyping ENSG00000015285 PMC3173800__F2 Two major pathways to caspase activation in vertebrates: the death receptor or extrinsic pathway, engaged by the indicated members of the TNF receptor family on the cell surface, and the Bcl-2-regulated mitochondrial or intrinsic pathway ENSG00000102871 ENSG00000168040 PMC11908393__F8 Tenascin-C induces microglial polarization through the TLR4/MyD88/NFKB pathway ENSG00000041982 ENSG00000172936 ENSG00000136869 PMC6420571__F6 Beta-Thujaplicin induces autophagic cell death, apoptosis, and cell cycle arrest through ROS-mediated Akt and p38/ERK MAPK signaling in human hepatocellular carcinoma ENSG00000143799 ENSG00000198793 ENSG00000277273 ENSG00000171791 PMC3841210__F7 FOLFIRI plus dulanermin (rhApo2L/TRAIL) in a patient with BRAF-mutant metastatic colon cancer ENSG00000020633 ENSG00000168036 ENSG00000168040 PMC5886582__F5 Signature pathway expression of xylose utilization in the genetically engineered industrial yeast Saccharomyces cerevisiae ENSG00000074800 ENSG00000196344 ENSG00000146909 ENSG00000100412 ENSG00000124253 ENSG00000146701 ENSG00000169299 ENSG00000013375 PMC6628492__F4 Synthesis of BDNF and potential downstream involved in the effects of botanicals and active components on depression ENSG00000198793 PMC6684519__F7 Hydrogen peroxide inducible clone-5 sustains NADPH oxidase-dependent reactive oxygen species-c-jun N-terminal kinase signaling in hepatocellular carcinoma ENSG00000076604 PMC4790586__F1 Signaling pathways involving the molecules reviewed ENSG00000100811 ENSG00000228716 ENSG00000168283 ENSG00000121068 ENSG00000122691 ENSG00000135446 ENSG00000136997 PMC2375563__F1 Muscle growth: no IGFs, ands, or buts ENSG00000198793 ENSG00000136997 PMC4615578__F9 The mechanisms of the miR-449a tumor suppressive function in neuroblastoma cells ENSG00000138795 ENSG00000144283 ENSG00000198860 ENSG00000166482 ENSG00000105810 PMC5790442__F9 Methylseleninic acid induces NAD(P)H:quinone oxidoreductase-1 expression through activation of NF-E2-related factor 2 in Chang liver cells ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC3153880__F3 Schematic representation of the effect of conventional treatment (Conv) and novel treatment (TKIs) on tumor behavior through the EGF-EGFR pathway ENSG00000138798 ENSG00000173599 ENSG00000146648 PMC6162711__F2 NFKB1 p105/p50 regulation of gene expression in cancer ENSG00000169245 ENSG00000081041 ENSG00000163220 ENSG00000163739 ENSG00000056558 ENSG00000099860 ENSG00000112715 ENSG00000146648 PMC2176131__F7 Collagen I Promotes Epithelial-to-Mesenchymal Transition in Lung Cancer Cells via Transforming Growth Factor–B Signaling ENSG00000138798 ENSG00000146648 PMC5807852__F7 RHBDD1 promotes metastasis in colorectal cancer ENSG00000144468 ENSG00000168036 PMC8080689__F1 Autophagy pathway ENSG00000152348 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC515190__F1 Cholesterol metabolism showing the physiological compartments involved ENSG00000042832 ENSG00000102977 PMC5750119__F9 Transcripts corresponding to most genes present in the KEGG Cell Cycle Pathway were increased in abundance in CCDs from rats on Day 2 of development of vasopressin-escape ENSG00000145604 ENSG00000144063 ENSG00000172005 ENSG00000277273 ENSG00000276876 PMC7102569__F1 Apoptosis signaling in response to infection ENSG00000164430 ENSG00000088888 ENSG00000164342 PMC10380530__F1 Comprehensive Review: Unveiling the Pro-Oncogenic Roles of IL-1ß and PD-1/PD-L1 in NSCLC Development and Targeting Their Pathways for Clinical Management ENSG00000278718 ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000090376 ENSG00000184216 PMC1763171__F2 The inflammatory, coagulation, and fibrinolytic pathways are linked at many levels, leading to organ failure and eventually death ENSG00000003436 ENSG00000134982 ENSG00000173599 ENSG00000122194 ENSG00000062485 PMC8772974__F3 Oxidative Stress Is a Key Modulator in the Development of Nonalcoholic Fatty Liver Disease ENSG00000164430 ENSG00000136869 ENSG00000175567 PMC8591135__F1 Toll-Like Receptors in Neuroimmune Diseases: Therapeutic Targets and Problems ENSG00000174123 ENSG00000174125 ENSG00000150455 ENSG00000182606 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000134070 ENSG00000157625 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 PMC5046039__F3 Bone remodeling: (a) in precursor cell stage, the macrophage-colony stimulating factor (M-CSF) binds to its receptor (c-Fms) ENSG00000095585 ENSG00000112977 ENSG00000120149 ENSG00000113140 ENSG00000108821 ENSG00000175104 ENSG00000163501 ENSG00000135605 ENSG00000010671 PMC8264285__F2 Targeting Tumor-Associated Antigen: A Promising CAR-T Therapeutic Strategy for Glioblastoma Treatment ENSG00000108849 ENSG00000132906 ENSG00000002330 ENSG00000138798 ENSG00000150907 ENSG00000198793 ENSG00000163914 ENSG00000168036 ENSG00000185591 ENSG00000171791 ENSG00000117322 PMC8591135__F3 Toll-Like Receptors in Neuroimmune Diseases: Therapeutic Targets and Problems ENSG00000174125 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC5872399__F5 The complexity of AM death Regulation following infection, trauma, and HS ENSG00000167207 ENSG00000189403 ENSG00000172936 ENSG00000136869 PMC8264285__F3 Targeting Tumor-Associated Antigen: A Promising CAR-T Therapeutic Strategy for Glioblastoma Treatment ENSG00000019991 ENSG00000149269 ENSG00000185591 PMC6136992__F2 Sending mixed signals: Cilia-dependent signaling during development and disease ENSG00000143147 ENSG00000173040 ENSG00000148384 ENSG00000164690 ENSG00000128602 PMC3469587__F7 SP-A-regulated signaling pathways in human macrophages ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC3962840__F5 Relationships between the cellular signal pathways in HAdV-36 infected human muscle cells ENSG00000165891 ENSG00000132824 ENSG00000175455 ENSG00000081277 ENSG00000091651 ENSG00000163661 ENSG00000151692 ENSG00000008083 ENSG00000065328 ENSG00000092470 ENSG00000170779 ENSG00000282899 ENSG00000158050 ENSG00000138092 PMC10033690__F1 Sex-differences in prostaglandin signaling: a semi-systematic review and characterization of PTGDS expression in human sensory neurons ENSG00000122420 ENSG00000050628 ENSG00000160013 ENSG00000125384 ENSG00000148344 ENSG00000124212 PMC9503107__F8 Cleistocalyx nervosum var. paniala Berry Promotes Antioxidant Response and Suppresses Glutamate-Induced Cell Death via SIRT1/Nrf2 Survival Pathway in Hippocampal HT22 Neuronal Cells ENSG00000173786 ENSG00000096717 PMC3765447__F3 Signaling pathways involving EPCAM, proposed by Maetzel D et al ENSG00000119888 ENSG00000134982 ENSG00000168036 PMC8187207__F9 Exercise training improves mitochondrial respiration and is associated with an altered intramuscular phospholipid signature in women with obesity ENSG00000198964 ENSG00000173599 ENSG00000164023 ENSG00000173402 PMC3465331__F6 In Vivo Tumorigenesis Was Observed after Injection of In Vitro Expanded Neural Crest Stem Cells Isolated from Adult Bone Marrow ENSG00000228716 ENSG00000149311 ENSG00000175054 ENSG00000101945 ENSG00000132646 PMC9508642__F8 Perindopril sensitizes hepatocellular carcinoma to chemotherapy: A possible role of leptin / Wnt/ Beta-catenin axis with subsequent inhibition of liver cancer stem cells ENSG00000134982 ENSG00000168036 ENSG00000100985 ENSG00000168610 PMC8873584__F1 SPINKs in Tumors: Potential Therapeutic Targets ENSG00000168610 PMC8416465__F2 How Perturbated Metabolites in Diabetes Mellitus Affect the Pathogenesis of Hypertension? ENSG00000168003 ENSG00000198793 ENSG00000173599 PMC7510303__F4 Diseases and regulator effects networks associated with the differentially expressed peptide precursors ENSG00000138722 ENSG00000168702 ENSG00000266265 ENSG00000054654 ENSG00000163702 ENSG00000082175 ENSG00000058453 ENSG00000164068 ENSG00000162896 ENSG00000168807 ENSG00000160145 ENSG00000167323 ENSG00000168356 ENSG00000266074 ENSG00000081052 ENSG00000184916 ENSG00000116984 ENSG00000115760 ENSG00000063176 ENSG00000164061 ENSG00000158055 ENSG00000143507 ENSG00000115266 ENSG00000131018 ENSG00000055609 ENSG00000123908 PMC9247709__F9 Schematic diagram illustrating how miR-21/PARP-1 activates the PI3K/AKT signaling pathway to induce EMT and migration of 16HBE cells ENSG00000170558 PMC7476571__F4 Viral miRNAs target genes involved in interferon signaling pathway ENSG00000159128 ENSG00000213928 ENSG00000115415 ENSG00000027697 ENSG00000107201 ENSG00000276561 ENSG00000142166 PMC11214299__F3 Exploiting the potential of the ubiquitin-proteasome system in overcoming tyrosine kinase inhibitor resistance in chronic myeloid leukemia ENSG00000135655 ENSG00000177169 ENSG00000181788 ENSG00000155313 ENSG00000170242 ENSG00000127334 ENSG00000129204 ENSG00000145604 ENSG00000110395 ENSG00000136997 ENSG00000115271 ENSG00000175104 ENSG00000148356 ENSG00000140464 ENSG00000109670 PMC5971008__F6 Chromatin Immunoprecipitation and DNA Sequencing Identified a LIMS1/ILK Pathway Regulated by LMO1 in Neuroblastoma ENSG00000108582 ENSG00000169756 ENSG00000107014 ENSG00000148484 ENSG00000166407 PMC7238203__F1 DNA sensing mechanisms through the cGAS/STING/TBK1 signaling pathway ENSG00000183735 ENSG00000164430 ENSG00000160703 PMC1507568__F3 The p53 response is triggered by many different stresses involving both DNA-damaging and non-DNA-damaging agents ENSG00000136997 ENSG00000168036 PMC2359939__F9 Proposed mechanism for RES induced apoptosis in LNCaP and PC-3 human prostate tumour cells ENSG00000105656 PMC7726415__F1 Major metabolism pathways by Nrf2 ENSG00000065833 ENSG00000135218 ENSG00000066926 ENSG00000167468 ENSG00000167996 ENSG00000169710 ENSG00000023909 PMC8393628__F2 Inflammatory Mediators, Macrophages, and Neutrophils in Glioma Maintenance and Progression: Mechanistic Understanding and Potential Therapeutic Applications ENSG00000019991 ENSG00000198793 ENSG00000136997 ENSG00000162924 ENSG00000175104 ENSG00000146648 PMC2064670__F5 Model integrating calcium mobilization into the Fas signaling pathway ENSG00000168040 ENSG00000026103 PMC2675492__F1 Biochemical schematics: This figure maybe regarded as the biochemical underpinning of our model ENSG00000163235 ENSG00000185591 PMC4282534__F5 Relationship of bm2 to the lignin biosynthetic pathway ENSG00000084774 ENSG00000116984 PMC4385913__F1 Cytotoxic agents impact the Bcl-2 rheostat ENSG00000002330 ENSG00000104081 PMC7730528__F4 Prolidase induces EGFR-downstream signaling pathway ENSG00000198793 ENSG00000146648 PMC7943879__F6 Forsythoside A (FTA) attenuates lipopolysaccharide (LPS)-induced endometritis by causing significant changes in the number of miRNAs in bESCs to regulate the target genes involved in different pathway ENSG00000134460 ENSG00000138755 ENSG00000197272 ENSG00000169429 ENSG00000136869 ENSG00000175104 PMC5730419__F2 Alternative signaling pathways of GFLs ENSG00000169291 ENSG00000180447 ENSG00000291971 PMC5832583__F5A Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism ENSG00000100412 ENSG00000146701 ENSG00000062485 PMC9323637__F3 Mutant p53, the Mevalonate Pathway and the Tumor Microenvironment Regulate Tumor Response to Statin Therapy ENSG00000185236 ENSG00000109819 ENSG00000112972 ENSG00000163914 ENSG00000113161 ENSG00000165527 PMC3426550__F6 SCS3 and YFT2 Link Transcription of Phospholipid Biosynthetic Genes to ER Stress and the UPR ENSG00000042832 ENSG00000173599 ENSG00000133124 ENSG00000184207 ENSG00000135517 PMC7672660__F5 Lipid mass spectrometry imaging and proteomic analysis of severe aortic stenosis ENSG00000186395 ENSG00000228278 ENSG00000188729 ENSG00000150337 ENSG00000000971 ENSG00000123561 ENSG00000127022 ENSG00000171791 ENSG00000163661 ENSG00000159189 ENSG00000137801 ENSG00000157131 ENSG00000211445 ENSG00000173369 ENSG00000113905 ENSG00000111537 ENSG00000145192 ENSG00000292002 ENSG00000128652 ENSG00000106624 ENSG00000158874 ENSG00000002549 ENSG00000127616 PMC7601667__F2 Cross-link between EMT-induced signalling pathways and Autophagy-inducedsignalling pathways ENSG00000169554 ENSG00000163235 ENSG00000138798 ENSG00000168036 PMC5646997__F2 Schematic representation of the effects of glutamate excitotoxicity, energy metabolism deficiency and axonopathy in ALS pathogenesis ENSG00000075213 PMC2771939__F1 Spatial Segregation of Phosphatidylinositol 4,5-Bisphosphate (PIP2) Signaling in Immune Cell Functions ENSG00000213658 ENSG00000070831 ENSG00000163914 PMC2039930__F7 Signal transduction pathways involved in Ha-ras-mediated AEG-1 induction ENSG00000136997 PMC4512107__F2 Let-7 targets insulin signaling pathway and thus inhibits cancer cell metabolism ENSG00000198793 ENSG00000136997 ENSG00000164327 ENSG00000026103 PMC4479845__F6 Chemokine Signaling Pathway Involved in CCL2 Expression in Patients with Rheumatoid Arthritis ENSG00000108691 ENSG00000277943 PMC9488681__F1 Pulmonary hypertension associated with neurofibromatosis type 1 ENSG00000198793 ENSG00000196712 PMC11619108__F3 Cnetplot of enriched pathways of DRPs identified through KEGG analysis ENSG00000291603 ENSG00000070831 ENSG00000241553 ENSG00000134215 ENSG00000170606 ENSG00000138071 ENSG00000165527 ENSG00000141968 ENSG00000111229 ENSG00000126803 ENSG00000149269 ENSG00000071051 ENSG00000277263 ENSG00000115091 ENSG00000231021 ENSG00000120837 ENSG00000162704 ENSG00000273686 ENSG00000043462 ENSG00000231925 ENSG00000105568 ENSG00000074211 ENSG00000281614 ENSG00000111537 ENSG00000224320 ENSG00000010810 ENSG00000171608 PMC5997832__F1 IRE1A structure and its downstream mechanisms in mild and severe stress ENSG00000100220 ENSG00000265972 ENSG00000100219 ENSG00000171791 PMC5997832__F2 IRE1A regulates the immune function through various mechanisms including both its kinase (A) and RNase (B) functions ENSG00000162711 ENSG00000150782 ENSG00000088888 ENSG00000137275 ENSG00000164136 ENSG00000136869 ENSG00000265972 ENSG00000231925 ENSG00000127191 ENSG00000106100 PMC7542964__F4 KEGG enrichment map of NOD-like receptor signaling pathway ENSG00000112977 ENSG00000156026 ENSG00000136997 PMC11619108__F2 Cnetplot of enriched pathways of DRPs identified through REACTOME analysis ENSG00000073584 ENSG00000163939 ENSG00000070831 ENSG00000173120 ENSG00000174744 ENSG00000142453 ENSG00000049618 ENSG00000132510 ENSG00000099381 ENSG00000066117 ENSG00000172534 ENSG00000149269 ENSG00000163914 ENSG00000004487 ENSG00000139613 ENSG00000162521 ENSG00000196498 ENSG00000123562 ENSG00000127337 ENSG00000196367 ENSG00000188486 ENSG00000071655 ENSG00000120656 ENSG00000147162 ENSG00000100345 ENSG00000176476 ENSG00000143933 ENSG00000198890 ENSG00000105968 ENSG00000172301 ENSG00000102710 ENSG00000162961 ENSG00000177565 ENSG00000126012 ENSG00000164105 ENSG00000167491 ENSG00000120533 ENSG00000101849 ENSG00000108604 ENSG00000092841 ENSG00000172977 ENSG00000089902 ENSG00000127616 ENSG00000196363 ENSG00000189079 ENSG00000149480 ENSG00000111642 PMC7913190__F2 Caspase-11 upregulation occurs as a result of PAMP and/or cytokine signaling and can be amplified by complement signaling ENSG00000162711 ENSG00000183735 ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000172005 ENSG00000172936 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000153002 PMC6153124__F1 Various published mechanisms of resistance to FMS-like tyrosine kinase 3 inhibitors ENSG00000122025 ENSG00000051180 ENSG00000184207 PMC7407660__F2 COP9 signalosome (CSN) partners with ubiquitin-specific protease 15 (USP15) and 48 (USP48) in the NFKB signaling pathway ENSG00000135655 ENSG00000100387 ENSG00000113558 ENSG00000090686 PMC11050207__F4 Significantly altered KEGG pathways in LAPST versus CPG group comparison ENSG00000012048 ENSG00000103479 ENSG00000157933 ENSG00000002330 ENSG00000102871 ENSG00000117400 ENSG00000198793 ENSG00000172936 ENSG00000127191 ENSG00000081189 ENSG00000026103 PMC11050207__F5 Significantly altered KEGG pathways in LAPST vs ENSG00000169291 ENSG00000136457 ENSG00000135218 ENSG00000002330 ENSG00000110799 ENSG00000173156 ENSG00000010810 ENSG00000149308 ENSG00000152592 PMC4628383__F1 Schematic representation of the brain microvasculature features and corresponding Impact of TS ENSG00000261371 ENSG00000162692 PMC7541012__F2 Roles of cancer‐associated fibroblasts (CAFs) in cancer chemoresistance ENSG00000019991 ENSG00000281324 ENSG00000133048 ENSG00000128342 ENSG00000171791 ENSG00000168610 PMC9117765__F2 TEAD4 as an Oncogene and a Mitochondrial Modulator ENSG00000186575 ENSG00000198793 ENSG00000163914 ENSG00000197905 ENSG00000020633 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC9117765__F3 TEAD4 as an Oncogene and a Mitochondrial Modulator ENSG00000186575 ENSG00000144560 ENSG00000198793 ENSG00000197905 ENSG00000020633 ENSG00000168036 ENSG00000150457 ENSG00000131023 ENSG00000196628 PMC9168599__F8 Activation of PI3K/p110A in the Lung Mesenchyme Affects Branching Morphogenesis and Club Cell Differentiation ENSG00000070193 ENSG00000125398 ENSG00000114315 ENSG00000016082 PMC8607377__F2 Cancer non-stem cells as a potent regulator of tumor microenvironment: a lesson from chronic myeloid leukemia ENSG00000169554 ENSG00000168610 PMC6448148__F1 Biosynthesis of all known wyosine bases ENSG00000198874 ENSG00000162971 PMC11718879__F1 Hedgehog signaling pathway ENSG00000164690 ENSG00000128602 PMC9632491__F1 Protein phosphorylation in cell signaling, disease, and the intervention therapy ENSG00000105664 ENSG00000002330 ENSG00000173156 PMC9632491__F3 Protein phosphorylation in cell signaling, disease, and the intervention therapy ENSG00000012048 ENSG00000175054 ENSG00000102871 ENSG00000198793 ENSG00000136997 ENSG00000171791 ENSG00000127191 PMC3922035__F5 Protein interaction network analysis of the up-regulated proteins in M ENSG00000143158 ENSG00000291814 ENSG00000120885 ENSG00000263238 ENSG00000136068 PMC4131037__F5 ChiBE overview ENSG00000111537 ENSG00000115415 ENSG00000033800 ENSG00000116030 PMC9632491__F8 Protein phosphorylation in cell signaling, disease, and the intervention therapy ENSG00000188486 ENSG00000087095 ENSG00000166813 ENSG00000136997 ENSG00000168036 PMC3535741__F1 PI3K/AKT/GSK3/mTOR signaling ENSG00000198793 ENSG00000168036 PMC9632491__F4 Protein phosphorylation in cell signaling, disease, and the intervention therapy ENSG00000135446 ENSG00000132646 ENSG00000136997 ENSG00000168036 ENSG00000205250 ENSG00000105810 ENSG00000001626 ENSG00000100632 PMC9632491__F5 Protein phosphorylation in cell signaling, disease, and the intervention therapy ENSG00000102871 ENSG00000149269 ENSG00000138798 ENSG00000127191 ENSG00000146648 PMC9632491__F6 Protein phosphorylation in cell signaling, disease, and the intervention therapy ENSG00000068028 ENSG00000122025 ENSG00000213928 ENSG00000291971 ENSG00000138798 ENSG00000169047 ENSG00000132478 ENSG00000146648 PMC4712335__F8 Age-related neuroinflammation and changes in AKT-GSK-3B and WNT/ Beta-CATENIN signaling in rat hippocampus ENSG00000004975 ENSG00000168036 ENSG00000168646 PMC9632491__F7 Protein phosphorylation in cell signaling, disease, and the intervention therapy ENSG00000163235 ENSG00000172936 ENSG00000168404 ENSG00000150455 PMC6468845__F3 Reprogramming of lipid metabolism under hypoxia ENSG00000162139 ENSG00000181788 ENSG00000169710 PMC7359022__F2 Release of HMGB1 protein and HMGB1 signaling pathways ENSG00000239732 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000121966 PMC4161359__F1 Mechanisms of AR pathway activation in CRPC PMC4161359__F2 Feedback pathways of AR, PTEN, and PI3K ENSG00000198793 ENSG00000177606 PMC3789182__F7 Schematic illustrating a model of NA anticancer activity is proposed ENSG00000138798 ENSG00000159399 PMC7359022__F4 Dual role of HMGB1 in chemoresistance ENSG00000198793 ENSG00000158828 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000077463 PMC8269070__F4 Dexamethasone for Severe COVID-19: How Does It Work at Cellular and Molecular Levels? ENSG00000115415 ENSG00000155974 PMC3860334__F7 Different vesicle transport pathways and the functions of Rab GTPases identified from the hUCBMSC MVs ENSG00000118508 ENSG00000172794 ENSG00000109113 ENSG00000168461 ENSG00000099246 ENSG00000119396 ENSG00000111737 PMC5761799__F8 Metabolic map of phenolic and glucosinolate metabolism in the primary inflorescence stems of the wild type, ccr1-6, and ccr1-6 ProSNBE:CCR1 lines ENSG00000102977 ENSG00000084774 PMC3431883__F3 Signaling mechanisms of oligodendrocyte injury ENSG00000115415 ENSG00000168040 ENSG00000026103 PMC7523401__F8 Target-Pathway network for HQ-BS anti-IBD ENSG00000132906 ENSG00000171105 ENSG00000105329 ENSG00000198793 ENSG00000173039 ENSG00000007908 ENSG00000112715 ENSG00000073756 ENSG00000168610 ENSG00000164305 ENSG00000132170 ENSG00000150782 ENSG00000169245 ENSG00000108691 ENSG00000111537 ENSG00000115415 ENSG00000177606 ENSG00000125538 ENSG00000169429 ENSG00000136869 ENSG00000100985 ENSG00000112115 ENSG00000162692 ENSG00000146648 PMC5896143__F1 Violacein biosynthetic pathway (a) and plasmid maps of the complete (b) and partial (c, d and e) operons for violacein biosynthesis ENSG00000065833 ENSG00000002330 ENSG00000042832 ENSG00000172005 ENSG00000084092 PMC7523401__F7 Distribution of partial targets of HQ-BS on the IBD pathway ENSG00000162594 ENSG00000134982 PMC6056925__F5 B cell receptor signaling pathway and network of anti-inflammation ENSG00000105369 ENSG00000170027 ENSG00000291971 ENSG00000007312 ENSG00000169032 ENSG00000010671 ENSG00000166592 ENSG00000179295 ENSG00000177455 ENSG00000281614 ENSG00000167941 ENSG00000186716 ENSG00000100985 ENSG00000124181 ENSG00000160293 PMC5576859__F7 Distinct Functions of Argonaute Slicer in siRNA Maturation and Heterochromatin Formation ENSG00000187446 ENSG00000198576 ENSG00000092847 PMC9539803__F1 Frontline workers: Mediators of mucosal immunity in community acquired pneumonia and COVID-19 ENSG00000169245 ENSG00000108691 ENSG00000081041 ENSG00000137033 ENSG00000130234 ENSG00000163739 ENSG00000138798 ENSG00000125538 ENSG00000108688 ENSG00000184012 ENSG00000169429 PMC3077220__F1 Hepatitis C Virus NS2 Protein Triggers Endoplasmic Reticulum Stress and Suppresses its Own Viral Replication ENSG00000144895 ENSG00000100219 PMC7962658__F6 Effects of Cryptotanshinone (Cts) on the Akt-GSK-3Beta-mPTP signaling pathway ENSG00000164305 PMC7030939__F7 Changes in the proteome of sea urchin Paracentrotus lividus coelomocytes in response to LPS injection into the body cavity ENSG00000131475 ENSG00000117525 ENSG00000130164 ENSG00000078053 ENSG00000069329 ENSG00000171540 ENSG00000140464 ENSG00000024422 PMC7030939__F8 Changes in the proteome of sea urchin Paracentrotus lividus coelomocytes in response to LPS injection into the body cavity ENSG00000003056 ENSG00000135218 ENSG00000170458 ENSG00000136869 ENSG00000005381 ENSG00000274145 ENSG00000213523 PMC8699276__F1 Targeting KRAS in NSCLC: Old Failures and New Options for “Non-G12c” Patients ENSG00000156299 ENSG00000149269 ENSG00000198793 ENSG00000140522 PMC5872597__F5 Celtis choseniana eethanol extract-mediated anti-inflammatory activity ENSG00000291971 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC6050907__F4 Neurotrophic signaling cascades ENSG00000138798 ENSG00000198793 ENSG00000134853 PMC5988709__F1 NNMT links NAD+ and methionine metabolism ENSG00000105835 ENSG00000133027 PMC8351122__F2 Fibroblast Growth Factor 19 in Hepatocellular Carcinoma ENSG00000160867 ENSG00000162595 ENSG00000148082 ENSG00000151365 ENSG00000143622 ENSG00000120913 ENSG00000168610 ENSG00000146648 ENSG00000196396 ENSG00000064300 ENSG00000160691 ENSG00000179295 PMC4694848__F7 Thioredoxin 1 mediates TGF-Beta-induced epithelial-mesenchymal transition in salivary adenoid cystic carcinoma ENSG00000170558 PMC4116528__F9 Snail regulates Nanog status during the epithelial–mesenchymal transition via the Smad1/Akt/GSK3B signaling pathway in non-small-cell lung cancer ENSG00000170365 PMC5341249__F2 Assays for the identification of G protein signalling pathways using the constitutive activity of an orphan GPCR ENSG00000197601 PMC3432651__F2 Involvement of the target of rapamycin (mTOR) pathway in human disease syndromes ENSG00000134086 ENSG00000186575 ENSG00000196712 PMC6954967__F8 Genes within the cGMP-PKG-Ca2+ signaling pathway altered via alternative splicing in the myocardium of DM and ChD mice ENSG00000274726 ENSG00000061273 ENSG00000291761 PMC7611834__F3 T regulatory cells as a potential therapeutic target in psychosis? Current challenges and future perspectives ENSG00000049768 ENSG00000168610 PMC8204251__F1 Therapy-Induced Tumor Cell Death: Friend or Foe of Immunotherapy? ENSG00000198793 ENSG00000168404 ENSG00000142166 PMC6406365__F1 A simplified model for canonical HhP ENSG00000128602 PMC9691967__F3 Tailoring biomaterials and applications targeting tumor-associated macrophages in cancers ENSG00000117525 ENSG00000186716 ENSG00000214285 PMC12100877__F2 Emerging roles of N6-methyladenosine (m6A) deregulation in polycystic ovary syndrome ENSG00000162711 ENSG00000125538 ENSG00000145321 ENSG00000107485 ENSG00000146457 PMC4669099__F3 Targeting BCR signaling attenuates homing, survival, EMDR and MRD of malignant B cells ENSG00000095585 ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000010671 PMC9396390__F2 Targeting tumor microenvironment for cholangiocarcinoma: Opportunities for precision medicine ENSG00000108691 ENSG00000138755 PMC2927952__F3 Insulin signaling pathway from PathVisio ENSG00000181929 ENSG00000171105 ENSG00000067057 ENSG00000163558 ENSG00000162409 ENSG00000067606 ENSG00000169047 ENSG00000169710 ENSG00000076555 ENSG00000132356 PMC5659938__F11 MiR-21-mediated suppression of Smad7 induces TGFB1 and can be inhibited by activation of Nrf2 in alcohol-treated lung fibroblasts ENSG00000105329 ENSG00000168610 PMC10419760__F1 TLR2 MyD88-dependent signaling pathway ENSG00000172936 ENSG00000157625 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC5662125__F1 Bile acid receptors link nutrient sensing to metabolic regulation ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC7488343__F7 Obesity, ER stress, miRNAs and endothelial function ENSG00000128272 ENSG00000100219 PMC2862089__F1 Signal transduction pathways and crosstalk activated by insulin/IGF-1 receptor and GPCR systems ENSG00000169047 ENSG00000198793 ENSG00000164327 PMC8904950__F5 Knockdown of TRIM44 inhibits the progression of ovarian cancer and is related to the FOXM1-EZH2 signaling pathway ENSG00000166326 ENSG00000125817 ENSG00000115163 ENSG00000101057 ENSG00000276644 ENSG00000112118 ENSG00000086758 ENSG00000138160 ENSG00000196628 ENSG00000197461 ENSG00000129173 ENSG00000101557 ENSG00000067066 ENSG00000177189 ENSG00000110395 ENSG00000089685 ENSG00000101255 ENSG00000019186 ENSG00000084652 ENSG00000162390 ENSG00000171848 ENSG00000124181 ENSG00000198947 PMC10609929__F2 Modeled DDIs for phenytoin ENSG00000165841 PMC4749929__F2 Pumping the breaks on B cell development ENSG00000095585 ENSG00000149311 ENSG00000137265 ENSG00000166211 PMC7019526__F1 Brain-derived neurotrophic factor (BDNF)/tropomyosin-related kinase receptor type B (BDNF/TrkB) signaling supports neuronal survival, plasticity, differentiation, and growth via activation of several functional downstream cascades ENSG00000124181 PMC8599992__F9 Exploring the Structures and Functions of Macromolecular SLX4-Nuclease Complexes in Genome Stability ENSG00000012061 ENSG00000149346 ENSG00000154920 ENSG00000188827 ENSG00000197299 ENSG00000178966 PMC8599992__F7 Exploring the Structures and Functions of Macromolecular SLX4-Nuclease Complexes in Genome Stability ENSG00000012061 ENSG00000109674 ENSG00000144554 ENSG00000188827 ENSG00000187790 PMC3566011__F8 HDAC6 Deacetylase Activity Is Required for Hypoxia-Induced Invadopodia Formation and Cell Invasion ENSG00000094631 ENSG00000140564 ENSG00000146648 PMC6413705__F1 Complement dysregulation in complement-mediated HUS Complement activation initiated by any of the three pathways (classical, alternative, or lectin pathway) leads to C3 activation and C3 convertase formation on C3-opsonized surfaces ENSG00000178726 PMC4706579__F3 IL-23/T17 pathogenic axis is an important therapeutic target in psoriasis ENSG00000162594 ENSG00000100906 ENSG00000162924 ENSG00000168610 PMC7200161__F6 Schematic model for possible signaling pathway related to the role of ALK7 in mediating BAT responses to nutrient stress ENSG00000163884 PMC7558805__F6 Sphingolipid biosynthetic pathways: ENSG00000228278 ENSG00000229314 PMC12022663__F8 Regenerative mechanisms induced by HAps encapsulated in hybrid hydrogels ENSG00000100345 ENSG00000196154 PMC9313589__F1 Pharmacological targets for the induction of ferroptosis: Focus on Neuroblastoma and Glioblastoma ENSG00000167468 ENSG00000168404 ENSG00000285379 PMC7024062__F1 CS response ENSG00000166278 ENSG00000236625 PMC3866163__F11 Global Assessment of Antrodia cinnamomea-Induced MicroRNA Alterations in Hepatocarcinoma Cells ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000145321 ENSG00000152689 ENSG00000010671 PMC9313589__F2 Pharmacological targets for the induction of ferroptosis: Focus on Neuroblastoma and Glioblastoma ENSG00000167468 ENSG00000168404 ENSG00000285379 PMC7308516__F2 Microbiota in cerebrovascular disease: A key player and future therapeutic target ENSG00000178860 ENSG00000134982 ENSG00000172936 ENSG00000145777 ENSG00000136869 ENSG00000185187 ENSG00000175104 ENSG00000184216 PMC9687595__F2 Wound Healing versus Metastasis: Role of Oxidative Stress ENSG00000181019 ENSG00000125538 ENSG00000086991 ENSG00000079999 PMC4128061__F2 Activation and regulation of BMP/Smad-dependent signalling ENSG00000137834 ENSG00000095739 ENSG00000198742 PMC4490281__F1 Simplified schema demonstrating proposed mGluR–eEF2–AMPAR pathway: Postsynaptic binding of glutamate leads to activation of ionotropic (AMPAR, NMDAR shown) and metabatropic (mGlu1/5 shown) glutamate receptors ENSG00000198793 ENSG00000284161 ENSG00000198576 ENSG00000167658 PMC8764638__F1 Reviewing clinical considerations and guideline recommendations of C1 inhibitor prophylaxis for hereditary angioedema ENSG00000039537 ENSG00000113600 ENSG00000122194 PMC6954967__F3 Genes of the cGMP-PKG-Ca2+ signaling pathway are alternatively spliced in cardiomyopathy: Role of RBFOX2 ENSG00000291761 ENSG00000101333 PMC7379131__F3 Inflammatory Tumor Microenvironment of GBM and its Therapeutic Implications ENSG00000102962 ENSG00000108691 ENSG00000107562 ENSG00000138798 ENSG00000049768 PMC9361616__F8 IFITM3 promotes malignant progression, cancer stemness and chemoresistance of gastric cancer by targeting MET/AKT/FOXO3/c-MYC axis ENSG00000019991 ENSG00000142089 PMC3188430__F7 miR-486 is an important regulator of PTEN/AKT signaling in normal and dystrophic muscle PMC7738626__F2 IFN-I response and signaling pathways in malaria parasite infections ENSG00000174125 ENSG00000213928 ENSG00000115267 ENSG00000175592 ENSG00000130589 ENSG00000127311 ENSG00000142166 ENSG00000135077 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000040933 ENSG00000136869 ENSG00000172936 ENSG00000291555 ENSG00000107201 ENSG00000131323 ENSG00000175104 PMC8467939__F4 Can the Mitochondrial Metabolic Theory Explain Better the Origin and Management of Cancer than Can the Somatic Mutation Theory? ENSG00000125166 ENSG00000083720 PMC7873978__F1 Lipoic acid metabolism pathways in E ENSG00000107798 ENSG00000105953 ENSG00000173239 PMC6349487__F3 TLR2, TLR3 and TLR9 regulate a robust immune response following HSV-1 infection ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC8055972__F8 Regulation of VM formation and NPC metastasis by the miR-124/Foxq1 axis ENSG00000087245 ENSG00000164379 ENSG00000100985 ENSG00000146648 PMC6519375__F7 CLIP‐170 controlling Met RTK recycling in migrating cells ENSG00000019991 PMC9324963__F2 IL‐22 in homeostasis and diseases of the skin ENSG00000105397 ENSG00000115415 ENSG00000198793 ENSG00000168610 PMC6710175__F3 Hepatocellular carcinoma development in the Mat1a knockout mouse ENSG00000130649 ENSG00000171791 PMC7574311__F3 Leaf-specific DEG attributed to photosynthesis are enhanced in SPL13RNAi plants ENSG00000124479 ENSG00000173599 PMC2442829__F1 Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations ENSG00000124102 ENSG00000198793 PMC4246083__F8 NLRP3 regulation by GPSM3 ENSG00000047410 ENSG00000162711 ENSG00000125538 PMC2442829__F2 Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations ENSG00000198793 ENSG00000146648 PMC4515859__F3 Biochemical network of arachidonic acid metabolism ENSG00000108839 ENSG00000179477 ENSG00000198704 ENSG00000120915 ENSG00000276870 ENSG00000095303 ENSG00000163751 ENSG00000179593 PMC4833611__F1 Nurr1 pathway and Nurr1‐based therapies for Parkinson's disease ENSG00000168036 ENSG00000185591 PMC7970560__F11 Modulating the PI3K-Akt signaling pathway and MAPK signaling pathway of ginseng against ALI/ARDS ENSG00000177455 ENSG00000087095 ENSG00000002330 ENSG00000102871 ENSG00000130522 ENSG00000186716 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000127191 ENSG00000081189 PMC6465620__F1 M6A function in AML ENSG00000145388 ENSG00000164944 ENSG00000162775 ENSG00000136997 ENSG00000126457 ENSG00000185591 ENSG00000115816 ENSG00000171791 ENSG00000146457 ENSG00000167182 ENSG00000165819 PMC8086041__F1 Pulmonary Macrophage Cell Death in Lung Health and Disease ENSG00000278718 ENSG00000132906 ENSG00000124256 ENSG00000115008 ENSG00000137033 ENSG00000168404 ENSG00000064012 ENSG00000164305 PMC2915669__F6 Model showing the interorganellar flow of acetyl units in C ENSG00000122966 PMC5811325__F2 Ras signaling pathways ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC3598331__F4 Hindlimb transcriptional regulatory pathway genes suggested to be important in talipes equinovarus pathogenesis ENSG00000203877 ENSG00000121075 PMC6830055__F1 Interplay between Metabolites and the Epigenome in Regulating Embryonic and Adult Stem Cell Potency and Maintenance ENSG00000147162 ENSG00000096717 PMC3524227__F1 Regulation of Mcl-1 by SRSF1 and SRSF5 in Cancer Cells PMC6889404__F1 hnRNPA2B1, an RNA-binding protein, can function as an m6A reader and is involved in RNA transport, processing or splicing ENSG00000122566 ENSG00000183735 ENSG00000164430 ENSG00000070495 ENSG00000163565 PMC3680752__F10 A: the top-associated network as defined by Ingenuity Pathway Analysis (IPA) for NAc mRNAs upregulated in HVRs vs ENSG00000146376 ENSG00000213465 ENSG00000059378 PMC11855299__F6 SMG modulates OBD by regulating the activity of both transcriptional and metabolic pathways ENSG00000096717 PMC4514105__F1 Cell death ENSG00000168040 ENSG00000026103 PMC6222792__F5 Pathway networks related to estrogen receptor alpha ENSG00000168209 ENSG00000154589 ENSG00000172893 ENSG00000198793 ENSG00000139269 ENSG00000108342 ENSG00000070669 ENSG00000285069 ENSG00000140835 ENSG00000169213 ENSG00000127533 ENSG00000092621 ENSG00000164161 ENSG00000134824 ENSG00000205809 ENSG00000283060 ENSG00000116761 ENSG00000172201 ENSG00000168772 ENSG00000062485 PMC4562806__F1 New immunotherapies targeting the PD-1 pathway ENSG00000134982 ENSG00000156127 ENSG00000198793 PMC4562806__F2 New immunotherapies targeting the PD-1 pathway ENSG00000138378 ENSG00000112715 ENSG00000168610 ENSG00000146648 ENSG00000131196 PMC6364001__F8 Proposed model of intracellular pathways engaged within, and functions of, HSV-specific CD8+ T cells from protected ASYMP individuals ENSG00000100385 ENSG00000134460 ENSG00000105397 ENSG00000115415 ENSG00000113088 ENSG00000168610 ENSG00000142166 PMC2955764__F1 Sonic hedgehog signaling pathway ENSG00000164161 ENSG00000164690 ENSG00000128602 PMC5821903__F1 Schematic overview of anabolic and catabolic signaling in skeletal muscle ENSG00000112964 ENSG00000198793 ENSG00000120729 ENSG00000140443 PMC10675221__F2 Results of the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis ENSG00000143799 ENSG00000140992 ENSG00000108443 ENSG00000171791 ENSG00000171720 ENSG00000082175 ENSG00000136869 ENSG00000001626 ENSG00000275565 ENSG00000140443 ENSG00000087245 ENSG00000101224 ENSG00000007171 ENSG00000151617 ENSG00000146648 ENSG00000162711 ENSG00000291971 ENSG00000050748 ENSG00000198793 ENSG00000196591 ENSG00000113161 ENSG00000145386 ENSG00000121879 ENSG00000196396 ENSG00000164305 ENSG00000010671 ENSG00000064300 ENSG00000179295 ENSG00000180210 ENSG00000149968 ENSG00000128052 ENSG00000123374 ENSG00000113263 ENSG00000124181 ENSG00000171105 ENSG00000259207 ENSG00000157764 ENSG00000173039 ENSG00000105639 ENSG00000006062 ENSG00000073756 ENSG00000168610 ENSG00000185386 ENSG00000115415 ENSG00000134057 ENSG00000135446 ENSG00000010810 ENSG00000177606 ENSG00000100985 ENSG00000149554 ENSG00000115232 PMC10675221__F3 Direct targets of the ethyl acetate extract from decoction of Sargentodoxa cuneata (EAdSc) action on the NOD-like receptor signaling pathway ENSG00000155926 ENSG00000156026 PMC7884719__F1 BDNF and MAP kinase pathways in combined portrait of depression ENSG00000160888 ENSG00000125740 ENSG00000033327 ENSG00000128512 ENSG00000134982 ENSG00000120875 ENSG00000159388 ENSG00000122877 ENSG00000265972 ENSG00000162772 ENSG00000112715 ENSG00000166068 ENSG00000171345 ENSG00000136826 ENSG00000186575 ENSG00000187678 ENSG00000136068 ENSG00000158050 ENSG00000136158 ENSG00000071575 ENSG00000143013 ENSG00000089041 ENSG00000116741 ENSG00000117152 ENSG00000169242 ENSG00000164171 ENSG00000164056 ENSG00000135750 ENSG00000198576 ENSG00000102893 ENSG00000154188 ENSG00000130508 ENSG00000114279 ENSG00000115461 ENSG00000164949 PMC7049344__F7 Proposed signaling pathway downstream of CD36 through which oxidized low-density lipoproteins (oxLDL) activate phosphodiesterase 3A (PDE3A) to suppress cyclic adenosine monophosphate (cAMP) signaling ENSG00000135218 ENSG00000172572 PMC7585656__F1 Reactive oxygen species- (ROS-) mediated inhibition of glycolysis reroutes flux into the oxidative arm of the pentose phosphate pathway PMC6301827__F7 Schematic representation of the relationship between Rab1a and the HIF-1a/miR-212-3p/Rab1a regulatory pathway in HCC proliferation and migration ENSG00000135446 ENSG00000123374 PMC5993211__F1 Innate Antiviral Immunity in the Skin ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000187608 ENSG00000089127 ENSG00000115415 ENSG00000185745 ENSG00000131323 ENSG00000125347 ENSG00000276561 PMC2872883__F2 TIF scores for genes in the KEGG colorectal cancer pathway ENSG00000142192 ENSG00000138795 ENSG00000002330 ENSG00000157764 ENSG00000292149 ENSG00000169032 ENSG00000121879 ENSG00000117020 ENSG00000089685 ENSG00000163914 ENSG00000177606 ENSG00000136997 ENSG00000171608 PMC6920888__F8 The anti-melanogenic mechanism of PS and PTS ENSG00000150787 PMC2872883__F3 Small cell lung cancer ENSG00000023445 ENSG00000104365 ENSG00000117020 ENSG00000110330 ENSG00000109320 ENSG00000056558 ENSG00000173039 ENSG00000131323 ENSG00000121879 ENSG00000175104 ENSG00000073756 PMC3994550__F1 Insulin signaling pathway ENSG00000005882 ENSG00000150907 ENSG00000169047 ENSG00000198793 PMC3906328__F1 IL-17 signaling and A20 ENSG00000123091 ENSG00000167207 ENSG00000078747 ENSG00000125538 ENSG00000175104 ENSG00000089053 PMC7331943__F3 Mitochondrial Substrate Utilization Regulates Cardiomyocyte Cell Cycle Progression ENSG00000135218 ENSG00000178999 ENSG00000173599 ENSG00000072110 ENSG00000166278 PMC5777758__F5 Tumor exome sequencing and copy number alterations reveal potential predictors of intrinsic resistance to multi-targeted tyrosine kinase inhibitors ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC9218738__F1 The NLRP3 Inflammasome in Mediating Glomerular and Tubular Injury in Diabetic Nephropathy ENSG00000278718 ENSG00000162711 ENSG00000137275 ENSG00000136869 ENSG00000168040 PMC5686346__F8 Proposed model of miR-130a mediated dysregulation of mTOR pathway in HGSOC ENSG00000198793 PMC3023470__F9 Schematic illustration of the sphingolipid metabolic pathway in CHO cells expressing SPHK1/2 and hSPNS2 ENSG00000063176 ENSG00000183018 PMC7563696__F3 Rho GTPases in spine morphogenesis ENSG00000106683 ENSG00000070831 ENSG00000149269 PMC3517549__F5 Evolution and Origin of Animal Toll-Like Receptor Signaling Pathway Revealed by Network-Level Molecular Evolutionary Analyses ENSG00000172005 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC5657420__F1 Classical pRb pathway demonstrates the utility of CDK inhibitors, such as palbociclib, in RB+/+ osteosarcoma ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC2955136__F3 Highly expressed proteins in MII oocytes ENSG00000182568 ENSG00000173039 ENSG00000106628 ENSG00000111642 ENSG00000164105 PMC3677579__F2 Accessory molecules for Toll-like receptors and their function ENSG00000174125 ENSG00000239732 ENSG00000136869 ENSG00000110057 ENSG00000164342 PMC2955136__F4 Highly expressed proteins in zygotes ENSG00000072134 ENSG00000111537 ENSG00000163902 ENSG00000131508 ENSG00000170142 ENSG00000273686 ENSG00000146701 ENSG00000291973 ENSG00000119048 ENSG00000062485 ENSG00000236625 ENSG00000163631 PMC7237728__F7 Effect of DFX on Mtb-infected macrophages PMC7924562__F1 Momelotinib and CFM4.16 synergistic combination ENSG00000168610 ENSG00000117399 PMC5731741__F4 FGMD: A novel approach for functional gene module detection in cancer ENSG00000186074 ENSG00000139572 ENSG00000105967 ENSG00000184060 ENSG00000101307 ENSG00000155926 ENSG00000104972 ENSG00000197629 ENSG00000158517 ENSG00000134061 ENSG00000091106 ENSG00000186818 ENSG00000185477 ENSG00000142347 ENSG00000274513 ENSG00000136286 ENSG00000180353 ENSG00000135838 ENSG00000166523 ENSG00000146094 ENSG00000104894 ENSG00000136869 ENSG00000139626 ENSG00000174125 ENSG00000283934 ENSG00000181804 ENSG00000088827 ENSG00000129226 ENSG00000174600 ENSG00000180061 ENSG00000110934 ENSG00000164691 ENSG00000134955 ENSG00000077420 ENSG00000167208 ENSG00000197093 ENSG00000184988 ENSG00000184922 ENSG00000049249 ENSG00000160219 ENSG00000198771 ENSG00000115232 ENSG00000171115 ENSG00000110077 ENSG00000145685 ENSG00000196209 PMC6528487__F1 Selected genomic alterations are indicated by an asterisk (*): fibroblast growth factor receptor (FGFR) pathway (FGF19, FGF4, FGF23, FGF3, and FGF6 amplifications) ENSG00000118972 ENSG00000198793 PMC3517549__F1 The Evolution and Origin of Animal Toll-Like Receptor Signaling Pathway Revealed by Network-Level Molecular Evolutionary Analyses ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC5731741__F3 FGMD: A novel approach for functional gene module detection in cancer ENSG00000244509 ENSG00000160185 ENSG00000172578 ENSG00000028277 ENSG00000163376 ENSG00000146859 ENSG00000186517 ENSG00000122224 ENSG00000020633 ENSG00000134061 ENSG00000121807 ENSG00000146192 ENSG00000138964 ENSG00000136286 ENSG00000177272 ENSG00000089012 ENSG00000133106 ENSG00000113263 ENSG00000163564 ENSG00000137078 ENSG00000110448 ENSG00000197471 ENSG00000198851 ENSG00000113088 ENSG00000009790 ENSG00000137841 ENSG00000173200 ENSG00000096996 ENSG00000104814 ENSG00000110934 ENSG00000164691 ENSG00000112303 ENSG00000163131 ENSG00000184922 ENSG00000026751 ENSG00000162692 ENSG00000198771 ENSG00000155629 PMC11762942__F3 Amino acid metabolism in chondrocytes ENSG00000125398 PMC8445033__F1 Convergent Loss of the Necroptosis Pathway in Disparate Mammalian Lineages Shapes Viruses Countermeasures ENSG00000124256 ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC4133236__F12 CXCL12 Induces Connective Tissue Growth Factor Expression in Human Lung Fibroblasts through the Rac1/ERK, JNK, and AP-1 Pathways ENSG00000107562 ENSG00000121966 PMC5988105__F1 Currently approved and available IBD therapies include: four anti-TNF agents, namely infliximab, adalimumab, certolizumab pegol, and golimumab, and two anti-integrin agents, natalizumab and vedolizumab ENSG00000099866 PMC12003104__F2 Relationship between iron metabolism disorder and diabetes and its complications ENSG00000173992 ENSG00000123191 ENSG00000177556 PMC5652951__F8 Schematic diagram of the role of IL-33 in the regulation of the biological behavior of glioma cells ENSG00000087245 ENSG00000137033 ENSG00000100985 PMC8616288__F2 FGF/FGFR-Dependent Molecular Mechanisms Underlying Anti-Cancer Drug Resistance ENSG00000140379 ENSG00000105397 ENSG00000171791 ENSG00000168610 PMC8616288__F3 FGF/FGFR-Dependent Molecular Mechanisms Underlying Anti-Cancer Drug Resistance ENSG00000019991 ENSG00000002330 ENSG00000170558 ENSG00000198793 PMC5988105__F2 SMAD pathway PMC5101236__F1 Schematic signaling pathways elicited by VEGF ENSG00000198793 ENSG00000128052 ENSG00000177606 ENSG00000136997 ENSG00000115904 PMC11762942__F4 Relationship between lipid metabolism and OA pathogenesis ENSG00000138135 ENSG00000086991 PMC6879798__F1 InterferonB signaling pathway regulated by RLRs ENSG00000088888 ENSG00000131323 ENSG00000121060 PMC526469__F6 Working model for SPRR1A activation in the myocardium ENSG00000169474 ENSG00000128342 ENSG00000168610 PMC9583737__F7 Wnt-mediated fibrosis in CD ENSG00000134982 PMC6165231__F1 Hedgehog (Hh) pathway activation ENSG00000164690 ENSG00000128602 ENSG00000146648 PMC4221415__F5 Identification of kinase inhibitor targets in the lung cancer microenvironment by chemical and phosphoproteomics ENSG00000197915 ENSG00000130413 ENSG00000203786 ENSG00000157404 ENSG00000141551 ENSG00000066926 ENSG00000105401 ENSG00000138964 ENSG00000183765 ENSG00000266173 ENSG00000168404 ENSG00000188677 ENSG00000182580 ENSG00000136535 ENSG00000117691 ENSG00000170027 ENSG00000169756 ENSG00000103202 ENSG00000132356 ENSG00000186442 ENSG00000111816 ENSG00000124588 ENSG00000131844 ENSG00000285379 ENSG00000146648 ENSG00000135605 ENSG00000131400 ENSG00000163512 ENSG00000186395 ENSG00000256671 ENSG00000050748 ENSG00000095015 ENSG00000087586 ENSG00000176105 ENSG00000169032 ENSG00000162302 ENSG00000182541 ENSG00000128050 ENSG00000169967 ENSG00000106683 ENSG00000136986 ENSG00000285176 ENSG00000263528 ENSG00000090376 ENSG00000106305 ENSG00000101213 ENSG00000155657 ENSG00000169567 ENSG00000172867 ENSG00000157764 ENSG00000128918 ENSG00000108828 ENSG00000263057 ENSG00000131023 ENSG00000111725 ENSG00000181929 ENSG00000284816 ENSG00000162733 ENSG00000148660 ENSG00000156110 ENSG00000162409 ENSG00000138756 ENSG00000143322 ENSG00000054118 ENSG00000145349 PMC9000186__F7 Rheostat of Ceramide and Sphingosine-1-Phosphate as a Determinant of Oxidative Stress-Mediated Kidney Injury ENSG00000063176 PMC9000186__F8 Rheostat of Ceramide and Sphingosine-1-Phosphate as a Determinant of Oxidative Stress-Mediated Kidney Injury ENSG00000063176 ENSG00000125538 PMC5835698__F2 Antitumor mechanisms of ivermectin ENSG00000213928 ENSG00000134982 ENSG00000100325 ENSG00000198793 ENSG00000168386 ENSG00000185745 ENSG00000168036 ENSG00000057663 ENSG00000172183 ENSG00000149269 ENSG00000135114 ENSG00000272398 ENSG00000026508 ENSG00000189403 ENSG00000168646 PMC9000186__F1 Rheostat of Ceramide and Sphingosine-1-Phosphate as a Determinant of Oxidative Stress-Mediated Kidney Injury ENSG00000100422 ENSG00000063176 PMC9504455__F2 Crosstalk between Glycogen-Selective Autophagy, Autophagy and Apoptosis as a Road towards Modifier Gene Discovery and New Therapeutic Strategies for Glycogen Storage Diseases ENSG00000177169 ENSG00000291507 ENSG00000112561 PMC7918477__F1 ER stress and unfolded protein response (UPR) signaling pathway ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC3110678__F3 SAT and PT domains of NSAS in aflatoxin B1biosynthetic pathway ENSG00000213614 ENSG00000049860 ENSG00000105205 PMC3068163__F1 Melanoma Molecular Disease Model ENSG00000002330 ENSG00000157764 ENSG00000135446 ENSG00000198793 ENSG00000088256 ENSG00000105810 PMC8745220__F5 Combination of Genomic and Transcriptomic Approaches Highlights Vascular and Circadian Clock Components in Multiple Sclerosis ENSG00000105664 ENSG00000111837 PMC7933806__F2 Sphingolipid networks ENSG00000100422 ENSG00000102172 PMC8395582__F5 ErbB signaling pathway map ENSG00000169291 ENSG00000002330 ENSG00000110395 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000136997 ENSG00000158458 ENSG00000169752 PMC4143607__F5 The role of the PHDs in the cell cycle ENSG00000145604 ENSG00000175054 ENSG00000101639 PMC6677404__F2 Schematic diagram illustrating a role of PI3K, Rho and ROCK pathways in hypoxia-induced ATP release and ATP-mediated angiogenic effects in vasa vasorum endothelial cells PMC2809919__F2 Epithelial–mesenchymal interactions mediated by the Sonic Hedgehog pathway in the gut ENSG00000106571 ENSG00000103241 ENSG00000164690 ENSG00000128602 PMC9524953__F6 Identification of a functional circRNA-miRNA-mRNA regulatory network in infantile hemangioma by bioinformatics analysis ENSG00000134086 ENSG00000069482 ENSG00000273529 ENSG00000133961 ENSG00000114315 ENSG00000168610 PMC10779236__F5 Possible action mechanisms of sialic acid mediated by the signaling pathway and gut environment ENSG00000159921 ENSG00000181019 ENSG00000172936 ENSG00000136869 PMC9445361__F6 Score of DNA damage repair pathway with the predictive ability for chemotherapy and immunotherapy is strongly associated with immune signaling pathway in pan-cancer ENSG00000139219 ENSG00000147381 ENSG00000163518 PMC7699575__F2 Glutathione (GSH) biosynthesis pathway ENSG00000168003 ENSG00000151012 ENSG00000167468 PMC7699575__F1 Ferroptosis pathway ENSG00000168003 ENSG00000167468 ENSG00000111684 PMC5997503__F5 PLATELET LIFELINE TO CANCER: CHALLENGES AND OPPORTUNITIES PMC10179536__F9 Proposed diagram for the therapeutic effect of PRP improved bladder overactivity induced by OHD in rat model ENSG00000125398 ENSG00000198793 ENSG00000026508 PMC5240474__F2 Inhibition of the NOTCH pathway by NUMB ENSG00000168214 ENSG00000148400 ENSG00000074181 ENSG00000133961 ENSG00000132964 ENSG00000184916 ENSG00000137845 PMC4988306__F2 Role of innate immunity in nonalcoholic fatty liver disease progression ENSG00000162711 ENSG00000239732 ENSG00000172936 ENSG00000136869 PMC10779236__F4 Main molecular mechanisms regulated by sialic acid ENSG00000159921 ENSG00000181019 ENSG00000172936 ENSG00000136869 PMC8699303__F6 Shooting at Moving and Hidden Targets—Tumour Cell Plasticity and the Notch Signalling Pathway in Head and Neck Squamous Cell Carcinomas ENSG00000122882 ENSG00000135547 ENSG00000198793 ENSG00000146648 PMC7308183__F6 Protein–protein interaction network of CFTR (GeneMANIA) ENSG00000101152 ENSG00000107562 ENSG00000188191 ENSG00000183943 ENSG00000109572 ENSG00000221869 ENSG00000001626 ENSG00000092820 ENSG00000277943 ENSG00000109705 ENSG00000033867 PMC8699303__F7 Shooting at Moving and Hidden Targets—Tumour Cell Plasticity and the Notch Signalling Pathway in Head and Neck Squamous Cell Carcinomas ENSG00000128917 PMC8946535__F1 From Biology to Treatment of Monoclonal Gammopathies of Neurological Significance ENSG00000095585 ENSG00000186716 ENSG00000134070 ENSG00000197943 ENSG00000010671 PMC5129989__F6 Higher methylation intensity induced by EBV LMP1 via NFKB/DNMT3b signaling contributes to silencing of PTEN gene ENSG00000127191 PMC7503990__F1 Structure and biosynthesis of fucosylated glycans ENSG00000196371 ENSG00000101346 ENSG00000112699 ENSG00000180549 ENSG00000130383 ENSG00000186866 PMC9040139__F4 Immunopathogenesis of alopecia areata ENSG00000105639 PMC9488956__F2 Hermansky–Pudlak syndrome pulmonary fibrosis: a rare inherited interstitial lung disease ENSG00000118508 ENSG00000107521 PMC9455597__F3 PARP inhibitor resistance in breast and gynecological cancer: Resistance mechanisms and combination therapy strategies ENSG00000175054 ENSG00000172716 ENSG00000227345 PMC9468871__F3 Network-based pharmacological investigation to identify the mechanistic regulatory pathway of andrographolide against colorectal cancer ENSG00000157404 ENSG00000291971 ENSG00000198793 ENSG00000134853 ENSG00000132170 ENSG00000179295 PMC9468871__F4 Network-based pharmacological investigation to identify the mechanistic regulatory pathway of andrographolide against colorectal cancer ENSG00000143799 ENSG00000157404 ENSG00000291971 ENSG00000198793 ENSG00000128052 ENSG00000136869 ENSG00000073756 ENSG00000168610 ENSG00000146648 ENSG00000164305 ENSG00000132170 ENSG00000179295 PMC5438742__F2 MYCN down-regulation by didymin and based on network analyses of our proteomic studies that focused on cancer-related pathways active in NB cells ENSG00000017797 ENSG00000070831 ENSG00000138798 ENSG00000163914 ENSG00000136997 ENSG00000146648 ENSG00000156273 PMC7340297__F5 Skeletal muscle dysregulation in rheumatoid arthritis: Metabolic and molecular markers in a rodent model and patients ENSG00000109819 ENSG00000171105 ENSG00000158022 ENSG00000109320 ENSG00000288174 ENSG00000150907 ENSG00000198793 ENSG00000169047 ENSG00000136869 ENSG00000112715 ENSG00000064300 ENSG00000132170 PMC4922562__F1 YAP/TAZ mechano-sensing signaling pathway network ENSG00000172005 PMC6911977__F5 Metabolic pathway for 2,3-butanediol production in yeast (modified, based on S ENSG00000275544 PMC12021614__F2 Multiple mechanisms of circRNA in tumor immunomodulation and immunotherapy PMC10848377__F2 Koetjapic acid molecular mechanism in curbing carcinogenesis ENSG00000171791 PMC2121320__F2 MTA family of coregulators in nuclear receptor biology and pathology ENSG00000162552 ENSG00000057935 ENSG00000149480 PMC8913720__F1 Functional Roles of Chemokine Receptor CCR2 and Its Ligands in Liver Disease ENSG00000108691 ENSG00000134982 ENSG00000108688 ENSG00000108700 ENSG00000168036 ENSG00000275095 ENSG00000121807 ENSG00000128602 PMC2910227__F3 Cellular Functions of Transient Receptor Potential channels ENSG00000171105 ENSG00000010671 PMC2228275__F3 A signaling network links genes regulated by GCs in CEM cells ENSG00000100714 ENSG00000015153 ENSG00000116649 ENSG00000125968 PMC5891012__F1 Dynamics and control of the ERK signaling pathway: Sensitivity, bistability, and oscillations ENSG00000146648 PMC3272882__F3 DRD2/GSK3B/DISC1 pathway modified from Beaulieu et al ENSG00000168036 ENSG00000149295 PMC8913720__F2 Functional Roles of Chemokine Receptor CCR2 and Its Ligands in Liver Disease ENSG00000108691 ENSG00000125538 ENSG00000108688 ENSG00000275095 ENSG00000121807 PMC8017015__F2 Regulated cell death pathways in doxorubicin-induced cardiotoxicity ENSG00000167468 ENSG00000197150 PMC3812667__F1 Bcl-2 inhibition may act directly on tumor cells but may also target the nutrient supply to the tumor by disrupting the blood vessels that form around, and within, the tumor () ENSG00000163739 ENSG00000169429 PMC6880955__F1 Signaling pathways of RIG-I-like receptors (RLRs), cGAS, and AIM2-like receptors (ALRs) ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000163568 PMC5998602__F10 The schematic illustrates a model of Long noncoding RNA HULC promotes liver cancer cell growth by inhibition of PTEN via autophagy cooperation to miR15a ENSG00000144848 ENSG00000096717 PMC3891517__F3 Possible mechanisms of opioid receptor-mediated influence of morphine on tumor growth ENSG00000002330 ENSG00000291971 ENSG00000138798 PMC7647673__F1 Transfer RNA-Derived Small RNAs: Another Layer of Gene Regulation and Novel Targets for Disease Therapeutics ENSG00000026297 PMC7647673__F2 Transfer RNA-Derived Small RNAs: Another Layer of Gene Regulation and Novel Targets for Disease Therapeutics ENSG00000132383 ENSG00000184916 ENSG00000134698 ENSG00000123908 PMC9696119__F5 Emerging Roles of Type-I Interferons in Neuroinflammation, Neurological Diseases, and Long-Haul COVID ENSG00000213928 ENSG00000185436 ENSG00000125347 ENSG00000276561 ENSG00000142166 ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000130234 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC10918910__F1 Mechanisms through which the gut microbiome contributes to oncogenesis ENSG00000168036 ENSG00000136869 ENSG00000140465 ENSG00000134716 ENSG00000106546 PMC10918910__F2 AhR activation by microbiome in the tumor microenvironment ENSG00000134982 ENSG00000140465 ENSG00000106546 PMC10850140__F7 Exploring the mechanism of action of Sparganii Rhizoma-Curcumae Rhizoma for in treating castration-resistant prostate cancer: a network-based pharmacology and experimental validation study ENSG00000002330 ENSG00000277893 ENSG00000123374 ENSG00000104368 PMC3135641__F1 Metabolic target genes of p53 ENSG00000135423 ENSG00000078237 ENSG00000284194 ENSG00000285069 ENSG00000080546 PMC7728070__F3 Modulating the autophagic machinery in vascular calcification ENSG00000147162 ENSG00000198793 PMC6938454__F1 Lab Review: Molecular Dissection of The Signal Transduction Pathways Associated with PTEN Deletion-Induced Optic Nerve Regeneration PMC5951826__F3 Wnt and Ras-MAPK pathway genes and interacting genes with AURKA, significantly deregulated (DEA) or in the most significantly deregulated gene module (Heinz) in the two cell lines, SW480 and Caco2 ENSG00000147044 ENSG00000100697 ENSG00000168036 ENSG00000087586 ENSG00000142733 ENSG00000166278 ENSG00000163631 ENSG00000221823 ENSG00000049130 ENSG00000213658 ENSG00000138166 ENSG00000072401 ENSG00000177606 ENSG00000134853 ENSG00000105810 ENSG00000168646 PMC4000109__F2 TGFB signalling cascade alterations that lead to prostate cancer ENSG00000105329 ENSG00000156574 ENSG00000130513 PMC6066750__F7 Role of Slfn2 in type I IFN signaling ENSG00000105397 ENSG00000100842 ENSG00000142166 PMC7784996__F3 Metabolism of Methylophaga aminisulidivorans SZUA-1124 ENSG00000090402 ENSG00000291368 PMC11675822__F2 NPFF and its receptors’ signaling pathways ENSG00000139574 ENSG00000148734 PMC4106421__F2 ARF impinges both on developmental processes (male germ cell development and ocular development in mice) and tumor angiogenesis ENSG00000149311 PMC5516115__F1 Speculative model on changes in carbon flux during P limitation in a diatom cell ENSG00000122966 ENSG00000173599 ENSG00000172005 PMC6534125__F2 Systemic Inflammation in Cancer-Associated Muscle Wasting and Rationale for Exercise as a Therapeutic Intervention ENSG00000152520 ENSG00000135903 PMC6437556__F1 Vitamin D metabolism and signaling ENSG00000111012 ENSG00000281324 ENSG00000019186 ENSG00000163914 ENSG00000104371 ENSG00000145321 ENSG00000124762 ENSG00000135929 PMC4773729__F2 Signaling mechanisms through the Janus kinase (JAK)/STAT pathway and action point of a JAK inhibitor tofacitinib ENSG00000105397 ENSG00000105639 PMC9674619__F4 Mechanism of mutp53 in ferroptosis ENSG00000168003 ENSG00000108839 ENSG00000135423 ENSG00000151012 ENSG00000155287 ENSG00000197635 ENSG00000066044 ENSG00000167468 ENSG00000073756 ENSG00000124762 ENSG00000166164 PMC11810975__F3 Synthesis of Primary BAs and Secondary BAs ENSG00000276559 ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC10149902__F12 Endothelial METRNL determines circulating METRNL level and maintains endothelial function against atherosclerosis ENSG00000275031 PMC6199354__F1 Ubiquitin modifications in the TGFB pathway ENSG00000135655 ENSG00000157933 ENSG00000070831 ENSG00000134982 ENSG00000036672 ENSG00000288488 ENSG00000187033 ENSG00000136826 ENSG00000203727 ENSG00000198742 ENSG00000164483 ENSG00000083799 ENSG00000175104 ENSG00000109670 PMC4761518__F1 F-BOX proteins in cancer cachexia and muscle wasting: emerging regulators and therapeutic opportunities ENSG00000169047 ENSG00000198793 PMC6199354__F2 Ubiquitin modifications in the WNT/Beta-catenin pathway ENSG00000135655 ENSG00000118518 ENSG00000116729 ENSG00000134982 ENSG00000198742 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000083799 ENSG00000101557 PMC3589701__F3 The epidermal growth factor receptor (EGFR) signaling pathway and molecules that may affect drug resistance ENSG00000019991 ENSG00000065361 ENSG00000198793 ENSG00000168610 ENSG00000146648 ENSG00000178568 PMC6920770__F4 Angiogenesis activation through reactive oxygen species (ROS) via hypoxia dependent and hypoxia independent pathways ENSG00000087245 ENSG00000198793 ENSG00000100985 PMC7736628__F1 Consequences of STING over-activation on antigen presenting cells and T cells following severe acute respiratory syndrome coronaviruses (SARS-CoV-2) infection ENSG00000177169 ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000173638 ENSG00000130234 ENSG00000276561 PMC3068308__F5 TGFB signaling pathway PMC7940873__F7 LncRNA-mRNA co-expression network analysis ENSG00000163739 ENSG00000134308 ENSG00000196468 ENSG00000099617 ENSG00000103479 ENSG00000175634 ENSG00000172216 ENSG00000186340 ENSG00000163734 ENSG00000164400 ENSG00000026103 ENSG00000023445 ENSG00000081041 ENSG00000137275 ENSG00000173039 ENSG00000065559 ENSG00000125347 ENSG00000107175 ENSG00000169245 ENSG00000108691 ENSG00000128272 ENSG00000101255 ENSG00000177606 ENSG00000184371 ENSG00000100784 ENSG00000188130 ENSG00000100985 ENSG00000123143 ENSG00000285379 ENSG00000028137 ENSG00000115009 PMC3043245__F3 Signalling between p53 and the IGF-AKT-mTORC1 pathway ENSG00000149311 PMC8796618__F12 MAGEA6 positively regulates MSMO1 and promotes the migration and invasion of oesophageal cancer cells ENSG00000136807 ENSG00000159479 ENSG00000113161 ENSG00000104973 ENSG00000125686 ENSG00000292195 PMC5588408__F1 Canonical and noncanonical inflammasomes ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000091592 ENSG00000091106 ENSG00000142166 ENSG00000276068 PMC9355307__F4 Sex chromosome aneuploidies give rise to changes in the circular RNA profile: A circular transcriptome-wide study of Turner and Klinefelter syndrome across different tissues ENSG00000064601 ENSG00000105835 ENSG00000146425 ENSG00000135218 ENSG00000138772 ENSG00000123728 ENSG00000197746 ENSG00000160710 ENSG00000110651 ENSG00000164327 ENSG00000151929 ENSG00000138071 ENSG00000137563 ENSG00000137845 ENSG00000101558 ENSG00000142166 ENSG00000292366 ENSG00000134996 ENSG00000285176 ENSG00000164713 ENSG00000183735 ENSG00000105497 ENSG00000188811 ENSG00000196549 ENSG00000117400 ENSG00000170043 ENSG00000168461 ENSG00000173930 ENSG00000095303 ENSG00000117335 ENSG00000196352 ENSG00000185591 ENSG00000136869 ENSG00000084733 ENSG00000120868 ENSG00000148346 ENSG00000172794 ENSG00000142192 ENSG00000159128 ENSG00000198931 ENSG00000027697 ENSG00000213341 ENSG00000273686 ENSG00000096063 ENSG00000185627 ENSG00000167996 PMC5495879__F3 Overlap of the present results with Greengard’s neurotransmission integration scheme ENSG00000073711 ENSG00000221914 ENSG00000167720 ENSG00000176533 ENSG00000100346 ENSG00000158445 ENSG00000149295 ENSG00000156475 ENSG00000178342 ENSG00000151834 ENSG00000079689 ENSG00000148841 ENSG00000157087 ENSG00000219435 ENSG00000143603 ENSG00000120903 ENSG00000080644 ENSG00000117971 ENSG00000116329 ENSG00000119121 ENSG00000164742 ENSG00000133107 ENSG00000150672 ENSG00000092020 ENSG00000142546 ENSG00000154146 PMC3418560__F5 Schematic representation of a case of malignant myeloid disease evolving in four stages along one pathway ENSG00000159216 ENSG00000171456 PMC9574103__F3 Comprehensive analysis of metabolomics and transcriptomics to reveal major metabolic pathways and potential biomarkers of human preeclampsia placenta ENSG00000108786 ENSG00000122787 ENSG00000140465 ENSG00000203857 PMC7596222__F4 Molecular pathways triggered by eCSF-derived factors ENSG00000170365 ENSG00000281324 ENSG00000134982 ENSG00000138798 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC6951466__F4 Ingenuity Pathway Analysis (IPA)‐based plausibility analysis of candidate single nucleotide polymorphisms (SNPs) ENSG00000087245 ENSG00000087460 PMC4961118__F1 Quantification of the input-response function of LAT:Grb2:SOS assembly in TCR signaling ENSG00000291603 ENSG00000213658 PMC10312032__F2 Research progress on the kynurenine pathway in the prevention and treatment of Parkinson’s disease PMC11715079__F1 Cytoplasmic recognition of HAdV DNA occurs through cGAS sensing ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000172936 PMC11715079__F2 Complement activation pathways and antibody neutralization effects of HAdV infection ENSG00000132109 ENSG00000244731 ENSG00000166278 ENSG00000236625 PMC8170089__F1 EndMT Regulation by Small RNAs in Diabetes-Associated Fibrotic Conditions: Potential Link With Oxidative Stress ENSG00000169554 ENSG00000111537 ENSG00000197635 ENSG00000067900 PMC11715079__F3 T-cells mediated adaptive immune responses ENSG00000111537 ENSG00000159216 ENSG00000134982 PMC8170089__F2 EndMT Regulation by Small RNAs in Diabetes-Associated Fibrotic Conditions: Potential Link With Oxidative Stress ENSG00000285070 ENSG00000166484 PMC4673677__F3 Surviving at a distance: organ specific metastasis ENSG00000087245 ENSG00000167772 ENSG00000113140 ENSG00000141753 ENSG00000162692 PMC2791157__F3 Decomposition of Gene Expression State Space Trajectories ENSG00000123374 PMC3521191__F1 Biological pathways targeted for therapy in renal cell carcinoma based on a knowledge of the underlying genetic changes and downstream biological consequences ENSG00000134086 PMC10949532__F1 Non-canonical NFKB pathway and its regulation: The non-canonical signaling pathway may be initiated through the binding of a variety of exogenous ligands to their cognate receptors (top right) ENSG00000104856 ENSG00000139193 ENSG00000186660 ENSG00000183735 ENSG00000264522 ENSG00000142405 ENSG00000111321 ENSG00000131323 ENSG00000127191 ENSG00000168610 PMC2989404__F1 Eighteen Insulin-like Growth Factor (IGF) pathway genes, circulating levels of IGF-1 and its binding protein (IGFBP-3), and risk of prostate and breast cancer ENSG00000197081 ENSG00000291972 ENSG00000112964 ENSG00000157005 PMC12034760__F0 FBL promotes hepatocellular carcinoma tumorigenesis and progression by recruiting YY1 to enhance CAD gene expression ENSG00000100811 ENSG00000168214 ENSG00000280548 ENSG00000084774 PMC4172779__F3 Downstream genes chosen from KEGG annotated in Wnt/Beta-catenin pathway ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000095739 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000148175 ENSG00000196470 PMC3159114__F10 Role of GPx-1 in modulating apoptosis ENSG00000026103 PMC7881565__F6 Distinct pathway for internalisation of MSN, MWCNT, and ZnO NPs in CHO-K1 cells: The proposed mechanism involved MSN and ZnO NPs uptake through clathrin-mediated endocytosis ENSG00000003056 ENSG00000149311 ENSG00000175054 ENSG00000101146 ENSG00000100330 ENSG00000135446 ENSG00000111237 ENSG00000214285 ENSG00000123374 ENSG00000088538 ENSG00000105810 ENSG00000145782 PMC8776968__F4 P21-activated kinases in neural cytoskeletal remodeling and related neurological disorders ENSG00000102879 ENSG00000070831 ENSG00000156299 ENSG00000170558 ENSG00000150625 ENSG00000128602 ENSG00000288461 PMC7654650__F2 Stem cells and lung regeneration ENSG00000186081 ENSG00000129654 ENSG00000176009 ENSG00000001626 ENSG00000168610 ENSG00000139352 ENSG00000170477 ENSG00000127074 PMC7654650__F4 Stem cells and lung regeneration ENSG00000171476 ENSG00000161798 ENSG00000162493 ENSG00000078081 ENSG00000167972 ENSG00000168484 PMC6528901__F4 Implications of 15‐LOX‐1 in angiogenesis in different models PMC7304922__F1 Activation of Nrf2 and AhR signaling pathways ENSG00000171759 ENSG00000106546 ENSG00000079999 PMC300841__F1 Usurpation of the Ras signaling pathway by reovirus ENSG00000291971 ENSG00000146648 PMC2390552__F11 ERK1 and ERK2 knockdown differently affect signals involved in patterning of the early embryo ENSG00000136158 ENSG00000133937 ENSG00000130700 ENSG00000198742 ENSG00000183691 ENSG00000156574 ENSG00000134363 ENSG00000149922 ENSG00000123124 ENSG00000187678 PMC4584981__F3 Model representing cross talk between drought and pathogen stress signaling pathway from individual stress studies and its relation to shared and unique response pathway provoked under combined stress ENSG00000105722 ENSG00000136997 PMC9240199__F3 Emerging Roles of Human Gut Microbiota in Gastrointestinal Cancer ENSG00000198793 ENSG00000185591 PMC2768997__F1 Human protein-protein interaction network of aging-associated genes ENSG00000149311 ENSG00000077150 ENSG00000109320 ENSG00000132646 ENSG00000136997 ENSG00000197299 ENSG00000116030 ENSG00000146648 ENSG00000196396 ENSG00000139687 ENSG00000140443 ENSG00000160691 PMC6271345__F6 Proposed mechanisms underlying the cellular responses to t-BHP after pre-treatment with Rb1 via Nrf2/HO-1 signaling pathway ENSG00000181019 ENSG00000178573 ENSG00000139687 ENSG00000079999 PMC4375817__F3 The modulation of downstream signaling pathways of the brain derived neurotrophic factors (BDNF) by glucocorticoids (GCs) ENSG00000145321 PMC8434356__F11 New Amino Acid Schiff Bases as Anticancer Agents via Potential Mitochondrial Complex I-Associated Hexokinase Inhibition and Targeting AMP-Protein Kinases/mTOR Signaling Pathway ENSG00000198793 ENSG00000171791 PMC7823834__F2 Agents acting on hormone signaling to revert drug resistance in CRC ENSG00000002330 ENSG00000159216 ENSG00000134982 ENSG00000150907 PMC2597859__F1 Role of Programmed Cell Death in the Immunopathogenesis of Sepsis ENSG00000002330 ENSG00000102871 ENSG00000168040 ENSG00000026103 PMC8700241__F2 Metabolic Reprogramming of Liver Fibrosis ENSG00000067992 ENSG00000067057 ENSG00000124253 ENSG00000159399 ENSG00000113742 PMC1440398__F2 CDC maturation upon virus infection ENSG00000088888 ENSG00000168040 PMC3539953__F5 Representation of the “Interferon Signaling” and “Toll-like Receptor Signaling” pathways ENSG00000033800 ENSG00000172936 ENSG00000150455 PMC4808550__F1 Thyroid hormone-signaling pathway ENSG00000291971 ENSG00000198793 ENSG00000168036 PMC3981821__F4 Prominent Steatosis with Hypermetabolism of the Cell Line Permissive for Years of Infection with Hepatitis C Virus ENSG00000131473 ENSG00000110921 ENSG00000112972 ENSG00000116133 ENSG00000172893 ENSG00000107798 ENSG00000113161 ENSG00000104549 ENSG00000106603 ENSG00000075239 ENSG00000167780 PMC6904332__F3 Upregulation of SESN2 under ERS and its protective effect on ERS-associated cell death ENSG00000128272 ENSG00000042832 ENSG00000144895 ENSG00000100219 ENSG00000127191 ENSG00000285069 PMC6904332__F4 The expression and effect of SESN2 on immune cells ENSG00000162711 ENSG00000125538 ENSG00000285069 PMC3981821__F6 Prominent Steatosis with Hypermetabolism of the Cell Line Permissive for Years of Infection with Hepatitis C Virus ENSG00000141349 ENSG00000262785 ENSG00000065911 ENSG00000278373 ENSG00000153574 ENSG00000135069 ENSG00000146733 ENSG00000284320 ENSG00000074800 ENSG00000229937 ENSG00000164708 ENSG00000136872 ENSG00000169299 PMC2435618__F2 Pathways involved in cell differentiation, homeostasis and apoptosis in the adult intestinal epithelium, Beta-catenin and TCF4 are expressed in the proliferative compartment, where are located the intestinal epithelial stem cells ENSG00000164690 ENSG00000163501 ENSG00000196628 PMC12191890__F5 Calcium signaling regulation in keratinocytes ENSG00000144935 ENSG00000177606 ENSG00000036828 PMC12191890__F6 Signaling pathways regulating epidermal homeostasis ENSG00000149311 ENSG00000175054 ENSG00000148400 ENSG00000138798 ENSG00000177606 ENSG00000171791 ENSG00000184916 PMC9089305__F8 Dimethyl Fumarate Ameliorates Doxorubicin-Induced Cardiotoxicity By Activating the Nrf2 Pathway ENSG00000079999 PMC9025760__F2 Characterization and Roles of Membrane Lipids in Fatty Liver Disease ENSG00000116688 ENSG00000173599 ENSG00000133027 PMC9099743__F1 Advances in Understanding the Genetic Basis of Fatty Acids Biosynthesis in Perilla: An Update ENSG00000173599 ENSG00000285482 ENSG00000062282 PMC10538549__F3 cGAS-STING signaling pathway in intestinal homeostasis and diseases ENSG00000164430 ENSG00000125538 PMC10538549__F1 cGAS-STING signaling pathway in intestinal homeostasis and diseases ENSG00000183735 ENSG00000213928 ENSG00000164430 ENSG00000105397 ENSG00000173638 ENSG00000197594 ENSG00000125538 ENSG00000163565 ENSG00000119457 ENSG00000168610 PMC10538549__F2 cGAS-STING signaling pathway in intestinal homeostasis and diseases ENSG00000150782 ENSG00000213658 ENSG00000160180 ENSG00000109321 ENSG00000113520 ENSG00000113525 ENSG00000293532 PMC11012409__F1 Agnostic Administration of Targeted Anticancer Drugs: Looking for a Balance between Hype and Caution ENSG00000012048 ENSG00000157764 PMC4373890__F2 Towards Anatomic Scale Agent-Based Modeling with a Massively Parallel Spatially Explicit General-Purpose Model of Enteric Tissue (SEGMEnT_HPC) ENSG00000168036 ENSG00000136869 ENSG00000168610 PMC4313349__F1 Nutrient Sensing Mechanisms and Pathways ENSG00000135218 ENSG00000113161 ENSG00000165280 PMC7465272__F1 STAT activation pathway with opportunities for inhibition ENSG00000120833 ENSG00000099985 ENSG00000291971 ENSG00000198793 ENSG00000086991 ENSG00000128342 ENSG00000049768 ENSG00000146648 ENSG00000062485 PMC6321520__F1 Expression of Insulin/IGF signaling components is modulated by miRNAs ENSG00000002330 ENSG00000081913 ENSG00000198793 ENSG00000169047 ENSG00000196396 PMC5907833__F3 Regulation of KLFs in ECs ENSG00000127528 ENSG00000136826 PMC7934645__F2 Regulatory roles and mechanisms of the transcription factor FOXF2 in human diseases ENSG00000100234 ENSG00000164379 ENSG00000176692 ENSG00000137273 ENSG00000171720 ENSG00000119669 ENSG00000168036 ENSG00000104332 ENSG00000146648 ENSG00000150630 PMC7934645__F3 Regulatory roles and mechanisms of the transcription factor FOXF2 in human diseases ENSG00000137273 ENSG00000166813 ENSG00000121067 ENSG00000128602 PMC4796284__F1 Postulated mechanism of PDGF-C-mediated liver fibrosis and tumor in Smad3-dependent and -independent signaling pathways ENSG00000134853 PMC4074033__F6 Kaposi Sarcoma Herpes Virus Latency Associated Nuclear Antigen Protein Release the G2/M Cell Cycle Blocks by Modulating ATM/ATR Mediated Checkpoint Pathway ENSG00000149311 ENSG00000175054 PMC7934645__F1 Regulatory roles and mechanisms of the transcription factor FOXF2 in human diseases ENSG00000170365 ENSG00000169554 ENSG00000137273 ENSG00000185591 PMC8125482__F3 Multifaceted Roles of USP15 in Signal Transduction ENSG00000135655 ENSG00000198793 PMC4988688__F2 Hedgehog (HH) signaling pathways ENSG00000128602 PMC4988688__F3 Activation and molecular crosstalk amongst signaling pathways ENSG00000281324 ENSG00000157764 ENSG00000162337 ENSG00000138798 ENSG00000168036 ENSG00000128602 ENSG00000168646 ENSG00000146648 PMC9315126__F5 Phosphoproteomics identifies pathways underlying the role of receptor‐interaction protein kinase 3 in alcohol‐associated liver disease and uncovers apoptosis signal‐regulating kinase 1 as a target ENSG00000160789 ENSG00000124256 ENSG00000156709 ENSG00000102871 ENSG00000151929 ENSG00000171791 ENSG00000168040 ENSG00000135341 ENSG00000148935 ENSG00000164305 ENSG00000160049 ENSG00000104237 ENSG00000119878 ENSG00000103490 ENSG00000263528 ENSG00000100813 ENSG00000064012 ENSG00000026103 PMC8326438__F10 Exploring effects of DNA methylation and gene expression on pan-cancer drug response by mathematical models ENSG00000215440 ENSG00000157404 ENSG00000100852 ENSG00000120885 ENSG00000076003 ENSG00000114019 ENSG00000183484 ENSG00000177455 ENSG00000122025 ENSG00000071282 ENSG00000053747 ENSG00000112739 ENSG00000178301 ENSG00000095303 ENSG00000104894 ENSG00000198108 ENSG00000168488 ENSG00000007384 ENSG00000100219 ENSG00000101197 ENSG00000184304 ENSG00000013375 ENSG00000112996 ENSG00000101160 ENSG00000109321 ENSG00000198561 ENSG00000182768 ENSG00000176428 ENSG00000170348 ENSG00000173402 ENSG00000157110 ENSG00000144935 ENSG00000100106 ENSG00000063660 ENSG00000146648 ENSG00000185567 ENSG00000292254 ENSG00000189079 ENSG00000182253 ENSG00000087510 ENSG00000019991 ENSG00000141384 ENSG00000204977 ENSG00000146247 ENSG00000198892 ENSG00000129351 ENSG00000137801 ENSG00000117054 ENSG00000164713 ENSG00000196935 ENSG00000152137 ENSG00000189403 ENSG00000112186 ENSG00000072422 ENSG00000135926 ENSG00000175787 ENSG00000006118 ENSG00000124839 ENSG00000160214 ENSG00000291873 ENSG00000150938 ENSG00000175874 ENSG00000135931 ENSG00000054690 ENSG00000131094 ENSG00000101265 ENSG00000105137 ENSG00000170390 ENSG00000171877 ENSG00000166133 ENSG00000107863 ENSG00000066455 ENSG00000159348 ENSG00000168077 ENSG00000115084 ENSG00000092199 ENSG00000180767 ENSG00000170638 ENSG00000133250 ENSG00000127311 ENSG00000187134 ENSG00000121897 ENSG00000111231 ENSG00000143061 ENSG00000106460 ENSG00000186716 ENSG00000167996 ENSG00000100941 ENSG00000162545 ENSG00000135404 ENSG00000102974 ENSG00000132341 ENSG00000150630 PMC4002948__F7 Possible molecular mechanisms by which Alpha-TOS overcomes the resistance of erbB2-expressing cells to apoptosis and sensitizes them to hrTRAIL-induced apoptosis ENSG00000113600 PMC11594131__F5 Possible ways of protective action of MKs and MKT in signaling and metabolic pathways under oxidative stress and heavy physical exercise ENSG00000198793 ENSG00000158828 ENSG00000096717 ENSG00000106459 PMC1832185__F2 Dose-dependent entry routes for the EGFR ENSG00000138798 ENSG00000146648 PMC7696406__F8A 8-Hydroxydaidzein, an Isoflavone from Fermented Soybean, Induces Autophagy, Apoptosis, Differentiation, and Degradation of Oncoprotein BCR-ABL in K562 Cells ENSG00000170458 ENSG00000102871 ENSG00000130159 ENSG00000081189 ENSG00000026103 PMC8468661__F7 Mitochondrial Disruption by Amyloid Beta 42 Identified by Proteomics and Pathway Mapping ENSG00000214078 ENSG00000134757 ENSG00000100345 ENSG00000171033 ENSG00000284468 ENSG00000163631 ENSG00000083857 ENSG00000007168 ENSG00000187688 ENSG00000004864 ENSG00000292099 ENSG00000180879 ENSG00000100078 ENSG00000168924 ENSG00000101608 PMC7610307__F3 GSK 3B regulates the key signaling proteins of the Wnt pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC7460588__F1 Canonical Wnt signaling pathway ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000183579 ENSG00000108375 ENSG00000196470 PMC4163887__F1 Role of Toll-like receptors during RSV infection ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC7610307__F4 Tumor inhibitory role of GSK 3B ENSG00000168036 PMC9266588__F3 Amino acid biosynthesis in Cyclocarya paliurus ENSG00000062485 PMC7435507__F1 Dihydroorotate dehydrogenase inhibitors in SARS‐CoV‐2 infection ENSG00000102967 ENSG00000084774 PMC7903655__F2 Mechanism by which MSCs regulate macrophage polarization in the context of SCI ENSG00000108691 ENSG00000118520 ENSG00000121807 PMC6299067__F2 Lysophosphatidic Acid 's effects on ion channel regulation ENSG00000163914 ENSG00000198670 ENSG00000196689 PMC8998506__F3 Mechanistic Insights into Selective Autophagy Subtypes in Alzheimer’s Disease ENSG00000133318 ENSG00000100219 ENSG00000184743 ENSG00000260916 PMC5348391__F9 Neurokinin-1 receptor is a novel positive regulator of Wnt/Beta-catenin signaling in melanogenesis ENSG00000134982 ENSG00000168036 PMC4673168__F5 ERBB activation modulates sensitivity to MEK1/2 inhibition in a subset of driver-negative melanoma ENSG00000157404 ENSG00000157764 ENSG00000109321 ENSG00000198793 ENSG00000088256 ENSG00000196712 PMC7683158__F2 SUMOylation in the hypoxia pathway ENSG00000094631 ENSG00000161956 PMC7683158__F3 SUMOylation in the nuclear factor kappa-light-chain-enhancer of activated B cells (NFKB) pathway ENSG00000149311 ENSG00000163904 PMC2717887__F2 Clusterin as a critical signaling node ENSG00000008516 ENSG00000005421 ENSG00000130522 ENSG00000177606 ENSG00000101057 ENSG00000168036 ENSG00000120885 PMC12150400__F3 Interaction between Trp metabolites and OA ENSG00000154736 ENSG00000125398 ENSG00000149968 ENSG00000086991 ENSG00000096717 ENSG00000106546 PMC1934514__F4 Schema outlining the signaling mechanisms reported to be involved in GLP-1R-induced differentiation/neogenesis of pancreatic precursor cells, proliferation and in the prevention of apoptosis ENSG00000124102 ENSG00000198793 ENSG00000146648 PMC12150400__F4 Interaction between Trp metabolites and OP ENSG00000019991 ENSG00000162711 ENSG00000198793 ENSG00000126457 ENSG00000142082 ENSG00000106546 ENSG00000170365 ENSG00000128272 ENSG00000198742 ENSG00000109685 ENSG00000175104 ENSG00000096717 ENSG00000131196 PMC1934514__F2 Mechanisms of Action of GLP-1 in the Pancreas ENSG00000124102 ENSG00000138798 ENSG00000150907 ENSG00000198793 PMC12150400__F6 Interaction between Trp metabolites and AS ENSG00000049768 ENSG00000168610 ENSG00000132693 PMC12150400__F1 Three pathways of Trp metabolism in the human body PMC12150400__F2 Bioactive effect of Trp metabolites in bone-related cells ENSG00000178860 ENSG00000170365 ENSG00000107562 ENSG00000125398 ENSG00000132646 ENSG00000106603 ENSG00000096717 ENSG00000131196 ENSG00000144476 ENSG00000121966 ENSG00000106546 ENSG00000158859 PMC2777399__F1 Regulatory mechanism of the Rho/ROCK pathway activated by angiotensin II (ANG II) in vascular smooth muscles cells (VSMCs, see text) ENSG00000065613 ENSG00000146648 PMC11311281__F4 PAR2-induced Beta-catenin stabilization and targets of RNF43 ENSG00000168036 ENSG00000108375 PMC8705244__F2 Alterations in Kynurenine and NAD+ Salvage Pathways during the Successful Treatment of Inflammatory Bowel Disease Suggest HCAR3 and NNMT as Potential Drug Targets ENSG00000105835 ENSG00000172890 ENSG00000278488 ENSG00000103257 ENSG00000241644 ENSG00000171097 ENSG00000137944 ENSG00000178685 ENSG00000106546 ENSG00000077009 ENSG00000129167 ENSG00000179097 ENSG00000157064 ENSG00000124523 ENSG00000173614 ENSG00000125166 ENSG00000162882 ENSG00000138617 ENSG00000183077 ENSG00000186038 ENSG00000178084 ENSG00000151883 ENSG00000156219 ENSG00000139287 ENSG00000255398 ENSG00000041880 ENSG00000106733 PMC3670237__F2 STAT3 regulation of and by microRNAs in development and disease ENSG00000291971 ENSG00000130522 ENSG00000168610 PMC6402958__F7 Models of TGFB superfamily signaling and Harmine-TGFB superfamily actions on human beta cell proliferation ENSG00000137834 ENSG00000133895 ENSG00000157540 ENSG00000136997 ENSG00000135414 ENSG00000123374 ENSG00000282899 PMC4003231__F1 Immune pathogenesis of gastric mucosa damage in H ENSG00000168040 ENSG00000115009 PMC3589238__F6 Networks wherein various signaling pathways epigenetically affected by MXC exposure intersect and the relationships between affected molecules ENSG00000171105 ENSG00000082175 ENSG00000140443 PMC6333638__F3 Cell-intrinsic PD-L1 in modulating signaling pathway ENSG00000168283 ENSG00000198793 ENSG00000244731 ENSG00000168610 PMC3958665__F6 KEGG pathway for Huntington's disease (proteins identified in our study of the PBMC proteome are highlighted by red stars) ENSG00000084093 ENSG00000232326 PMC6319582__F7 Diagram of knockdown of TFPI-anchored endothelial cells induced a more severe LPS-induced acute lung injury via NFKB signaling pathway ENSG00000003436 ENSG00000130234 ENSG00000136869 ENSG00000162692 PMC5751326__F1 InterferonB (IFNB) signaling pathways and autocrine/paracrine loop ENSG00000155966 ENSG00000239732 ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 PMC5751326__F2 Role of IFNB in host–pathogen interaction in Mtb infection ENSG00000162711 ENSG00000183735 ENSG00000164430 ENSG00000163568 ENSG00000125538 PMC7683158__F1 SUMOylation pathway ENSG00000012048 ENSG00000136997 ENSG00000168036 PMC9171887__F1 SARS-CoV2 and mitochondria: the impact on cell fate ENSG00000171791 PMC2639747__F2 Smad3 in TGFB–mediated proapoptotic transcriptional responses ENSG00000198793 ENSG00000099860 ENSG00000171791 PMC5473921__F2 Network of organismal abnormalities and cancer ENSG00000188643 ENSG00000173221 ENSG00000110031 ENSG00000130204 ENSG00000149084 ENSG00000163993 ENSG00000034510 ENSG00000122786 ENSG00000291973 PMC2639747__F1 Smad3 in TGFB–induced antiproliferative transcriptional responses ENSG00000133740 ENSG00000185591 ENSG00000205250 PMC7831445__F3 The innate immune response to human coronavirus infection ENSG00000213928 ENSG00000187608 ENSG00000276561 ENSG00000007171 ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000130234 ENSG00000184012 ENSG00000172936 ENSG00000164342 PMC8505811__F2 Muscle-Bone Crosstalk in Chronic Obstructive Pulmonary Disease ENSG00000175104 ENSG00000062485 PMC8505811__F1 Muscle-Bone Crosstalk in Chronic Obstructive Pulmonary Disease ENSG00000198793 ENSG00000175104 ENSG00000131196 PMC3859915__F2 Signaling downstream IL-2/IL-15RB ENSG00000198793 ENSG00000105639 PMC3376493__F4 A Human Homeotic Transformation Resulting from Mutations in PLCB4 and GNAI3 Causes Auriculocondylar Syndrome ENSG00000065135 ENSG00000006377 ENSG00000149782 ENSG00000151617 ENSG00000101333 PMC7865811__F3 NFKB pathway by NLRX1 ENSG00000088888 ENSG00000160703 ENSG00000172936 ENSG00000175104 PMC6291014__F1 Signaling pathways linking EphA and RhoA in regulation of cell adhesion/repulsion ENSG00000070831 ENSG00000291971 ENSG00000149269 ENSG00000163914 PMC7572606__F1 MYC transcriptionally upregulates the glutamine metabolism pathway ENSG00000105939 ENSG00000198793 ENSG00000160710 ENSG00000265972 ENSG00000126261 ENSG00000128050 ENSG00000011422 ENSG00000078081 ENSG00000136997 ENSG00000185591 ENSG00000184900 ENSG00000115419 ENSG00000009307 ENSG00000280548 ENSG00000100906 ENSG00000183048 ENSG00000137275 ENSG00000142230 ENSG00000101361 ENSG00000160182 ENSG00000013306 ENSG00000111801 ENSG00000060491 ENSG00000102034 ENSG00000059378 ENSG00000171848 ENSG00000172936 ENSG00000111331 ENSG00000121060 ENSG00000123268 ENSG00000159399 ENSG00000084774 PMC6291014__F4 A model of EphB forward signaling regulating cell-ECM adhesion ENSG00000087245 ENSG00000133216 PMC5706935__F1 PARK2 loss connects AMPK-mediated nitrosative stress to PI3K/AKT activation ENSG00000291971 ENSG00000110931 ENSG00000146648 PMC6009929__F1 Synthetic pathway for preparation of II-V [reagents; i = NC-CH2-CN, ii = (CH3CO)2CH2, iii = (NH2)2C = NH, iv = NH2NH2, v = MeI] ENSG00000108582 ENSG00000100473 PMC8076597__F1 Road of Solid Tumor Survival: From Drug-Induced Endoplasmic Reticulum Stress to Drug Resistance ENSG00000284774 ENSG00000128272 ENSG00000137275 ENSG00000050748 ENSG00000164362 ENSG00000168036 ENSG00000151929 ENSG00000100219 ENSG00000145782 ENSG00000127191 ENSG00000057663 PMC3286676__F1 Thyroid iodide efflux: a team effort? ENSG00000042832 ENSG00000140279 ENSG00000165409 PMC4867322__F1 The Hippo signal transduction network and its links to exercise-associated signals and signalling modules ENSG00000144560 ENSG00000197905 ENSG00000151929 ENSG00000007866 ENSG00000100294 ENSG00000131023 ENSG00000074219 PMC3742302__F6 Omics-Based Molecular Target and Biomarker Identification ENSG00000149311 ENSG00000175054 ENSG00000101224 PMC3630382__F7 Ingenity Pathway Analysis (IPA) from genes with loss of heterozygosity and somatic mutation (sample G05) ENSG00000102753 ENSG00000196131 ENSG00000186047 ENSG00000146385 ENSG00000204977 ENSG00000147138 ENSG00000102539 ENSG00000136146 ENSG00000086015 ENSG00000179348 ENSG00000102468 ENSG00000139687 PMC3630382__F8 "Cancer, Hematological Disease, Cell Cycle" Network ENSG00000181163 ENSG00000027644 ENSG00000281877 ENSG00000086015 ENSG00000143125 ENSG00000245848 ENSG00000095587 ENSG00000143162 ENSG00000136527 ENSG00000164754 ENSG00000128482 ENSG00000179348 ENSG00000118900 PMC3630382__F9 Major interaction in top network ENSG00000050327 ENSG00000245848 ENSG00000181163 ENSG00000136527 ENSG00000179348 PMC5098112__F6 Manually curated version of RISN ENSG00000178096 ENSG00000002330 ENSG00000134982 PMC9609926__F4 Activation of Host Cellular Signaling and Mechanism of Enterovirus 71 Viral Proteins Associated with Hand, Foot and Mouth Disease ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000157625 ENSG00000168040 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC8601392__F4 Dynamic Interaction Between Mucosal Immunity and Microbiota Drives Nose and Pharynx Homeostasis of Common Carp (Cyprinus carpio) After SVCV Infection ENSG00000142192 ENSG00000110514 ENSG00000137392 ENSG00000121060 PMC8987327__F5 Prolyl hydroxylase domain proteins in bone metabolism ENSG00000136807 ENSG00000141867 ENSG00000138336 PMC9042931__F4 Protein–protein interaction networks between NAD+ and associated regulatory proteins implicated in heart aging ENSG00000266173 ENSG00000198793 ENSG00000173039 ENSG00000168040 ENSG00000142082 ENSG00000026103 PMC8592830__F1 Regulatory host factors and interacting viral proteins of the RLR-mediated antiviral signaling pathway ENSG00000164164 ENSG00000164091 ENSG00000172046 ENSG00000175592 ENSG00000163132 ENSG00000162191 ENSG00000265491 ENSG00000166851 ENSG00000180667 ENSG00000183735 ENSG00000171720 ENSG00000088888 ENSG00000078747 ENSG00000108679 ENSG00000104228 ENSG00000162601 ENSG00000108106 ENSG00000171109 ENSG00000087095 ENSG00000132109 ENSG00000147162 ENSG00000276561 ENSG00000127334 ENSG00000273992 ENSG00000158717 ENSG00000188021 ENSG00000100505 ENSG00000102007 ENSG00000177981 ENSG00000131323 ENSG00000083799 ENSG00000198746 ENSG00000122779 ENSG00000121060 ENSG00000100304 ENSG00000277276 ENSG00000144837 ENSG00000133135 PMC9042931__F2 Schematic diagram illustrating intracellular pathways of NAD+ synthesis, NAD+ metabolism, and NAD+ signaling pathway in mitochondria ENSG00000164638 ENSG00000105835 ENSG00000123572 ENSG00000221955 ENSG00000262217 ENSG00000122696 ENSG00000112992 ENSG00000112759 ENSG00000008130 ENSG00000142082 ENSG00000198246 PMC3976587__F7 Post-Transcriptional Regulation of Cytokine Signaling by AU-Rich and GU-Rich Elements ENSG00000101109 ENSG00000070831 ENSG00000137275 ENSG00000145365 ENSG00000102871 ENSG00000020633 ENSG00000171791 ENSG00000159216 ENSG00000172216 ENSG00000177606 ENSG00000082512 ENSG00000134070 ENSG00000172936 ENSG00000185591 ENSG00000175104 ENSG00000064012 ENSG00000028137 ENSG00000285379 ENSG00000184216 PMC8592830__F2 Regulatory host factors and interacting viral proteins of the cGAS-mediated antiviral signaling pathway ENSG00000136271 ENSG00000159461 ENSG00000137699 ENSG00000164663 ENSG00000292211 ENSG00000108654 ENSG00000265491 ENSG00000136014 ENSG00000196396 ENSG00000198925 ENSG00000183735 ENSG00000164430 ENSG00000165312 ENSG00000197594 ENSG00000160703 ENSG00000106266 ENSG00000143258 ENSG00000124422 ENSG00000125826 ENSG00000147548 ENSG00000125347 ENSG00000276561 ENSG00000159714 ENSG00000184979 ENSG00000127445 ENSG00000163904 ENSG00000136878 ENSG00000128272 ENSG00000123609 ENSG00000142089 ENSG00000083799 ENSG00000175104 ENSG00000123908 ENSG00000130726 PMC2563180__F3 The cardiofaciocutaneous syndrome ENSG00000157764 PMC3045531__F9 Snail repressor is required for PMC ingression in the sea urchin embryo ENSG00000198125 PMC7307344__F1 LncRNAs in osteosarcoma via PI3K/Akt signaling pathway PMC1899931__F8 Theoretical model depicting potential interactions in the intra-S checkpoint signaling pathway ENSG00000175054 ENSG00000164053 ENSG00000111602 PMC4996735__F1 Redox signaling: an evolution from free radicals to aging ENSG00000181019 ENSG00000291971 ENSG00000079999 PMC8978522__F6 RING finger protein TOPORS modulates the expression of tumor suppressor SMAR1 in colorectal cancer via the TLR4‐TRIF pathway ENSG00000197579 ENSG00000136869 ENSG00000131323 ENSG00000168610 PMC6726644__F9 Schematic overview of metabolic pathways of P ENSG00000112977 ENSG00000084093 ENSG00000213614 ENSG00000145020 PMC7901903__F1 Gasdermins in pore formation and pyroptotic cell death ENSG00000278718 ENSG00000163914 ENSG00000167914 ENSG00000073605 PMC4303254__F3 Gene product interaction network of immune and inflammatory responsive genes associated with smoking in females generated from the information in the Ingenuity knowledge base, version 7.6 ENSG00000170011 ENSG00000150045 ENSG00000274429 ENSG00000159733 ENSG00000100867 ENSG00000144824 ENSG00000088826 ENSG00000139187 ENSG00000204136 ENSG00000174844 ENSG00000181104 ENSG00000124491 ENSG00000150687 ENSG00000189430 ENSG00000120885 ENSG00000163737 ENSG00000062524 ENSG00000184500 ENSG00000156475 ENSG00000154917 ENSG00000065833 ENSG00000111796 ENSG00000159674 ENSG00000158321 ENSG00000007402 ENSG00000041353 ENSG00000128886 ENSG00000171596 ENSG00000197461 ENSG00000197959 ENSG00000112984 ENSG00000168229 ENSG00000106153 ENSG00000145649 ENSG00000074966 ENSG00000026751 ENSG00000115523 ENSG00000138738 PMC8822281__F6 miR-3132 upregulates surface TRAIL to induce apoptotic cell death in cancer cells ENSG00000183735 ENSG00000213928 ENSG00000172936 PMC8226237__F3 Machine Learning Approach to Differentiate Two Specific Breast Cancer Subtypes Using Androgen Receptor Pathway Genes ENSG00000010017 ENSG00000170606 ENSG00000167333 PMC12075064__F2 Pathway insertion strategy into a Δadh P ENSG00000002330 PMC6441206__F3 Regulatory network of ferroptosis ENSG00000156873 ENSG00000163930 ENSG00000151012 ENSG00000125144 ENSG00000129596 ENSG00000078668 ENSG00000167468 ENSG00000197429 ENSG00000122873 ENSG00000136381 ENSG00000079999 PMC138699__F1 Simplified diagram of the canonical Wnt/Beta-catenin signaling pathway ENSG00000134982 ENSG00000168036 PMC11960914__F9 Schematic diagram of PHB1 and PHB2 expression in blood vessel wall cells and the possible molecular pathways in terms of adhesion of ECs and proliferation, migration, and autophagy of VSMCs ENSG00000198793 ENSG00000100985 ENSG00000162692 PMC8026611__F7 Ferroptosis: molecular mechanisms and health implications ENSG00000168003 ENSG00000159128 ENSG00000111537 ENSG00000151012 ENSG00000105329 ENSG00000115415 ENSG00000167468 ENSG00000027697 ENSG00000118520 ENSG00000168610 ENSG00000057663 PMC8026611__F2 Ferroptosis: molecular mechanisms and health implications ENSG00000072274 ENSG00000113161 ENSG00000169710 ENSG00000086065 ENSG00000168003 ENSG00000076554 ENSG00000104549 ENSG00000111371 ENSG00000115107 ENSG00000034693 ENSG00000135423 ENSG00000138449 ENSG00000151012 ENSG00000197635 ENSG00000196839 ENSG00000078668 ENSG00000157911 ENSG00000007171 ENSG00000176108 ENSG00000167468 ENSG00000111684 ENSG00000167996 ENSG00000042286 ENSG00000110911 ENSG00000116761 ENSG00000127948 PMC4561113__F3 Notch-signalling pathway in macrophage reprogramming and its interaction with the TLR-dependent signalling pathway ENSG00000140968 ENSG00000136869 ENSG00000168610 PMC3875397__F1 FOXO transcription factors throughout T cell biology ENSG00000149311 ENSG00000163599 ENSG00000127528 ENSG00000049768 PMC8026611__F5 Ferroptosis: molecular mechanisms and health implications ENSG00000138449 ENSG00000116044 ENSG00000151012 ENSG00000125144 ENSG00000066926 ENSG00000178573 ENSG00000167468 ENSG00000167996 ENSG00000023909 ENSG00000079999 PMC3635988__F12 HCV-Induced miR-21 Contributes to Evasion of Host Immune System by Targeting MyD88 and IRAK1 ENSG00000172936 ENSG00000276561 ENSG00000184216 ENSG00000142166 PMC1862519__F1 Intracellular signaling cascades activated by BDNF-stimulated autophosphorylation of TrkB receptors may affect prominent pathways responsible for elevations of intracellular Ca2+ levels in neurons ENSG00000124102 ENSG00000169291 PMC3640296__F2 Therapeutic targeting of microenvironmental interactions in leukemia: mechanisms and approaches ENSG00000026508 ENSG00000168036 ENSG00000168610 ENSG00000121966 ENSG00000159399 PMC3640296__F3 Therapeutic targeting of microenvironmental interactions in leukemia: mechanisms and approaches ENSG00000198793 ENSG00000168036 ENSG00000168610 ENSG00000121966 PMC8906750__F1 Monolignol pathway metabolite levels in the C. hassleriana seed coat ENSG00000112977 ENSG00000084774 PMC6635480__F1 Targeting pathways and molecules in the treatment of NMSC ENSG00000124102 ENSG00000002330 ENSG00000198793 ENSG00000128602 ENSG00000146648 PMC9366312__F3 Overcoming Mycobacterium tuberculosis through small molecule inhibitors to break down cell wall synthesis ENSG00000123999 PMC9231138__F11 Dihydrotanshinone I Enhances Cell Adhesion and Inhibits Cell Migration in Osteosarcoma U−2 OS Cells through CD44 and Chemokine Signaling ENSG00000150907 ENSG00000026508 ENSG00000169429 ENSG00000168610 PMC10855920__F2 Innate and adaptative immune systems ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC10855920__F4 Molecular pathways hypothesized to be involved in the pathogenesis of nonspecific orbital inflammation ENSG00000186810 ENSG00000111537 ENSG00000137033 ENSG00000102970 ENSG00000172936 ENSG00000131323 ENSG00000175104 PMC8283099__F5 Complex analysis of the personalized pharmacotherapy in the management of COVID-19 patients and suggestions for applications of predictive, preventive, and personalized medicine attitude ENSG00000292250 ENSG00000291876 PMC9102749__F6 System-level investigation of anti-obesity effects and the potential pathways of Cordyceps militaris in ovariectomized rats ENSG00000169291 ENSG00000171791 ENSG00000127948 ENSG00000171345 PMC12065145__F7 Schematic diagram illustrates the mechanism by which high Hcy levels promote hypertension PMC4395781__F6 Representation of the proposed mechanism of action for CM-hfMSCs on insulin-like growth factor (IGF)-expressing cells ENSG00000115457 ENSG00000169047 ENSG00000140443 PMC9035223__F1 Fleshy fruit ripening: from transcription factors to epigenetic modifications ENSG00000105722 ENSG00000168374 PMC10474116__F3 Pathways of mitochondrial quality control ENSG00000128272 ENSG00000169136 ENSG00000069509 ENSG00000136758 ENSG00000125656 ENSG00000106459 PMC1974879__F1 Transcriptional profile of Rous Sarcoma Virus transformed chicken embryo fibroblasts reveals new signaling targets of viral-src ENSG00000003436 ENSG00000291971 ENSG00000134363 ENSG00000022267 ENSG00000275565 PMC108887__F9 The CD5-induced signaling pathway, which is mediated by PI 3-kinase and Vav, resulting in the activation of Rac1 ENSG00000110448 ENSG00000010810 PMC4145816__F1 Ras/MAPK signaling cascade and small molecule inhibition ENSG00000157764 ENSG00000115904 PMC8541918__F4 Compartmentation of the Wnt pathway by LLPS ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8541918__F5 Phosphorylation regulates Hippo pathway LLPS ENSG00000015285 ENSG00000150457 ENSG00000131023 PMC10474116__F4 Apoptotic signaling pathways ENSG00000100290 ENSG00000120868 ENSG00000168040 PMC4456143__F2 Alterations in DNA Methylation May Be the Key to Early Detection and Treatment of Schistosomal Bladder Cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000168036 PMC5097896__F6 The Activin/TGFB mediated Smad2/3 signaling pathway ENSG00000156574 PMC10751868__F5 H19: An Oncogenic Long Non-coding RNA in Colorectal Cancer ENSG00000122566 ENSG00000124216 PMC8716617__F2 Pannexin Channel Regulation of Cell Migration: Focus on Immune Cells ENSG00000110218 ENSG00000154096 ENSG00000103335 PMC8506768__F6 Bioinformatic analysis of differentially expressed genes and pathways in idiopathic pulmonary fibrosis ENSG00000068028 ENSG00000189283 ENSG00000019991 ENSG00000002330 ENSG00000105639 ENSG00000146648 ENSG00000122008 ENSG00000132341 PMC3634910__F1 Nutrient Signaling to mTOR and Cell Growth ENSG00000145979 ENSG00000196712 PMC3634910__F2 Nutrient Signaling to mTOR and Cell Growth ENSG00000198793 ENSG00000145979 PMC3634910__F3 Nutrient Signaling to mTOR and Cell Growth ENSG00000145979 PMC9138746__F3 Scratching the Surface—An Overview of the Roles of Cell Surface GRP78 in Cancer ENSG00000241186 ENSG00000175899 ENSG00000168040 ENSG00000166851 PMC7057487__F4 Interactive network for the 8 enriched signaling transduction pathways ENSG00000185634 ENSG00000157404 ENSG00000058085 ENSG00000160551 ENSG00000188784 ENSG00000087008 ENSG00000150093 ENSG00000184381 ENSG00000145431 ENSG00000012048 ENSG00000106571 ENSG00000186340 ENSG00000156299 ENSG00000157087 ENSG00000276870 ENSG00000100078 ENSG00000197943 ENSG00000120251 ENSG00000077782 ENSG00000140443 ENSG00000196712 ENSG00000115008 ENSG00000005339 ENSG00000157764 ENSG00000005961 ENSG00000078369 ENSG00000140795 ENSG00000070961 ENSG00000189056 ENSG00000158458 ENSG00000169752 ENSG00000067606 ENSG00000185231 ENSG00000136160 ENSG00000162104 ENSG00000156113 PMC7840724__F8 Schematic model for radiation induced opposite invasion and migration potential in HCT116 and DLD-1 cells ENSG00000182718 PMC4931107__F1 snR81 box H/ACA RNP-catalyzed pseudouridylation ENSG00000145912 ENSG00000109534 ENSG00000291996 ENSG00000145321 PMC2955618__F6 Runx2-regulated cancer-related gene network ENSG00000198785 ENSG00000106236 ENSG00000162772 ENSG00000055955 ENSG00000131470 ENSG00000141232 ENSG00000245848 ENSG00000159216 ENSG00000136997 ENSG00000095303 ENSG00000187908 ENSG00000164400 ENSG00000171621 ENSG00000282899 ENSG00000130513 ENSG00000138449 ENSG00000204103 ENSG00000138131 ENSG00000085117 ENSG00000077984 ENSG00000116741 ENSG00000144354 ENSG00000167034 ENSG00000166033 ENSG00000145220 ENSG00000094804 ENSG00000175745 ENSG00000150672 ENSG00000100479 ENSG00000169908 ENSG00000157193 ENSG00000087085 ENSG00000020633 ENSG00000164399 ENSG00000124107 ENSG00000112715 ENSG00000127129 ENSG00000112312 ENSG00000137801 ENSG00000144677 ENSG00000095739 ENSG00000129214 ENSG00000124664 ENSG00000134258 ENSG00000149418 ENSG00000137834 ENSG00000148346 ENSG00000149577 ENSG00000003436 ENSG00000064393 ENSG00000096088 ENSG00000145604 ENSG00000153208 ENSG00000100749 ENSG00000019549 ENSG00000141526 PMC7864581__F7 Nitric oxide prevents aortic valve calcification by S-nitrosylation of USP9X to activate NOTCH signaling ENSG00000148400 ENSG00000101752 PMC2724780__F1 Bile acid modulation of death and survival transduction pathways ENSG00000132906 ENSG00000002330 ENSG00000168040 ENSG00000164305 PMC3899118__F5 Genome Wide Expression Analysis Suggests Perturbation of Vascular Homeostasis during High Altitude Pulmonary Edema ENSG00000157184 ENSG00000117054 ENSG00000106617 ENSG00000175065 ENSG00000140285 ENSG00000165409 ENSG00000180616 ENSG00000188763 ENSG00000151617 ENSG00000106178 PMC7450103__F1 Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target ENSG00000128050 PMC7814972__F1 Deoxynivalenol (DON)biosynthetic pathway ENSG00000160752 ENSG00000110921 ENSG00000255690 ENSG00000167508 PMC7189445__F1 Hexosamine Biosynthetic Pathway (HBP) and O-GlcNAcylation ENSG00000147162 ENSG00000198408 ENSG00000124357 ENSG00000013375 PMC6361427__F8 Fine mapping of the major QTL for seed coat color in Brassica rapa var. Yellow Sarson by use of NIL populations and transcriptome sequencing for identification of the candidate genes ENSG00000084774 PMC11413889__F9 MetaCore pathway analysis of Schlafen 5 (SLFN5) co-expressed genes in COAD patients from TCGA ENSG00000108691 ENSG00000291814 ENSG00000121966 PMC4742192__F10 Auranofin induces apoptosis by ROS-mediated ER stress and mitochondrial dysfunction and displayed synergistic lethality with piperlongumine in gastric cancer ENSG00000132906 ENSG00000128272 ENSG00000144895 ENSG00000164305 PMC5891592__F2 CXCR4–CXCR7 crosstalk affecting signaling pathways ENSG00000169248 ENSG00000107562 ENSG00000121966 PMC10531073__F3 Fluconazole-Induced Protein Changes in Osteogenic and Immune Metabolic Pathways of Dental Pulp Mesenchymal Stem Cells of Osteopetrosis Patients ENSG00000197043 ENSG00000067842 ENSG00000080819 ENSG00000226784 ENSG00000084733 ENSG00000179820 ENSG00000100504 ENSG00000198125 ENSG00000139687 PMC10958717__F2 Oxidized lipids and cholesterol affect MSC differentiation ENSG00000178860 ENSG00000138798 PMC6168163__F2 Maintaining maximal metabolic flux by gene expression control ENSG00000105656 ENSG00000132693 PMC5022012__F4 An integrative study identifies KCNC2 as a novel predisposing factor for childhood obesity and the risk of diabetes in the Korean population ENSG00000140575 ENSG00000165059 ENSG00000166006 PMC6522716__F5 Differential expression and bioinformatics analysis of circRNA in osteosarcoma ENSG00000124102 ENSG00000197429 PMC11638432__F6 The mechanism of PTX3 regulation of innate immunity and ferroptosis after LPS challenge ENSG00000163661 ENSG00000115009 ENSG00000112486 PMC5022012__F3 An integrative study identifies KCNC2 as a novel predisposing factor for childhood obesity and the risk of diabetes in the Korean population ENSG00000078900 ENSG00000036672 ENSG00000161203 ENSG00000170606 PMC9121581__F5 Potential effects and mechanisms of hispidulin in the treatment of diabetic retinopathy based on network pharmacology ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000179091 ENSG00000186716 ENSG00000198793 ENSG00000104894 PMC8775349__F1 Tilting the Balance: Therapeutic Prospects of CD83 as a Checkpoint Molecule Controlling Resolution of Inflammation ENSG00000139187 ENSG00000170458 ENSG00000125538 ENSG00000107485 ENSG00000112149 ENSG00000049768 ENSG00000184216 PMC2981611__F1 Wnt Signaling and Mammary Stem Cells ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000291971 ENSG00000168036 PMC5120243__F5 Network model for CTNNB1 and related genes ENSG00000019991 ENSG00000138795 ENSG00000142627 ENSG00000005339 ENSG00000090402 ENSG00000044115 ENSG00000134982 ENSG00000169862 ENSG00000148400 ENSG00000140575 ENSG00000198561 ENSG00000168036 ENSG00000070886 ENSG00000196396 ENSG00000164151 ENSG00000124216 ENSG00000122691 ENSG00000113318 ENSG00000136997 ENSG00000145321 ENSG00000146648 ENSG00000127616 ENSG00000198286 PMC8909289__F1 miRNA-Dependent Regulation of AKT1 Phosphorylation ENSG00000138798 ENSG00000164329 PMC12204025__F2 Canonical insulin signaling pathway ENSG00000171105 ENSG00000169047 PMC9129976__F3 Fructus Mume Pills Underlying Their Protective Effects in Rats with Acetic Acid-Inducedulcerative Colitis via the Regulation of Inflammatory Cytokines and the VEGF-PI3K/Akt-eNOS Signaling Pathway ENSG00000167601 ENSG00000114200 ENSG00000178999 ENSG00000291971 ENSG00000103222 ENSG00000126261 ENSG00000106546 ENSG00000180210 ENSG00000185015 ENSG00000129214 ENSG00000128052 ENSG00000095303 ENSG00000100504 ENSG00000087245 ENSG00000171105 ENSG00000142192 ENSG00000131747 ENSG00000073756 ENSG00000108839 ENSG00000117650 ENSG00000107854 ENSG00000105426 ENSG00000005381 ENSG00000074410 ENSG00000146648 PMC9459425__F1 Cold adaptation strategies in plants—An emerging role of epigenetics and antifreeze proteins to engineer cold resilient plants ENSG00000164151 ENSG00000110395 PMC9129976__F4 Fructus Mume Pills Underlying Their Protective Effects in Rats with Acetic Acid-Inducedulcerative Colitis via the Regulation of Inflammatory Cytokines and the VEGF-PI3K/Akt-eNOS Signaling Pathway ENSG00000087245 ENSG00000171105 ENSG00000073756 ENSG00000118777 ENSG00000007171 ENSG00000106546 ENSG00000132170 ENSG00000180210 ENSG00000149968 ENSG00000095303 ENSG00000105426 ENSG00000100985 ENSG00000005381 ENSG00000146648 PMC12239985__F3 Hypoxia-inducible factor 1-alpha (HIF-1A) signaling pathway ENSG00000074800 ENSG00000138798 PMC2601664__F1 Membrane-initiated Estrogen Signaling in Hypothalamic Neurons ENSG00000291971 ENSG00000113070 ENSG00000138798 ENSG00000146648 PMC8790028__F3 Opioids Regulate the Immune System: Focusing on Macrophages and Their Organelles ENSG00000239732 ENSG00000172936 PMC4450349__F1 Of flies, mice and men: Evolutionarily conserved tissue damage responses and aging ENSG00000136997 ENSG00000132478 PMC7471874__F11 Expression patterns of genes in IL-1 Signaling Pathway upon EI24 silencing ENSG00000172936 ENSG00000130159 ENSG00000175104 PMC6041899__F7 Quercetin inhibits gastric cancer metastasis ENSG00000087245 ENSG00000106683 ENSG00000149269 ENSG00000100985 PMC5369955__F9 Sub-lethal oxidative stress induces lysosome biogenesis via a lysosomal membrane permeabilization-cathepsin-caspase 3-transcription factor EB-dependent pathway ENSG00000005893 ENSG00000112561 PMC5675827__F7 Ingenuity Pathway Analysis (IPA) comparisons of the quantified readouts from ENSG00000104689 ENSG00000123144 ENSG00000276618 ENSG00000291971 ENSG00000168040 ENSG00000115317 PMC7920909__F2 SARS-CoV-2 Replication ENSG00000130234 ENSG00000163631 PMC4712384__F2 HCV replication cycle ENSG00000142627 ENSG00000130164 ENSG00000015520 ENSG00000110651 ENSG00000146648 PMC12240182__F1 Novel AR axis-directed therapy for the treatment of metastatic prostate cancer PMC3265067__F7 Phospholipid biosynthetic pathways ENSG00000185813 ENSG00000173599 ENSG00000133027 PMC4712384__F4 Evasion of innate immunity by HCV viral proteins ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000144895 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000164342 PMC8479296__AF1 LINC01094 promotes pancreatic cancer progression by sponging miR-577 to regulate LIN28B expression and the PI3K/AKT pathway ENSG00000187772 ENSG00000123908 PMC8465210__F10 Oncogenic Signaling Disruptor, NDRG1: Molecular and Cellular Mechanisms of Activity ENSG00000134982 ENSG00000168036 PMC4672200__F3 Schematic of the proposed non-canonical Wnt signaling pathway induced in the ceca from experimental chickens with persistent colonization by Salmonella Enteritidis ENSG00000168036 PMC2885424__F7 Transcriptional Regulation of the IGF Signaling Pathway by Amino Acids and Insulin-Like Growth Factors during Myogenesis in Atlantic Salmon ENSG00000011566 ENSG00000167779 ENSG00000169047 ENSG00000198793 ENSG00000140443 PMC8465210__F15 Oncogenic Signaling Disruptor, NDRG1: Molecular and Cellular Mechanisms of Activity ENSG00000019991 ENSG00000291971 PMC5120243__F4 Network model for CTNNB1 ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC6470689__F1 Proposed oncogenic mechanisms for Plk1 ENSG00000084093 ENSG00000197579 ENSG00000136997 ENSG00000075218 ENSG00000166851 ENSG00000178691 PMC5527948__F1 Scheme depicting the major compartments of the endocytic pathway and selected endocytic proteins participating in the transmission of signaling to the nucleus, by affecting the transcription machinery and/or the chromatin‐remodeling factors ENSG00000149136 ENSG00000155975 ENSG00000074319 ENSG00000105656 ENSG00000168036 ENSG00000028528 ENSG00000133961 PMC7471098__F7 Impaired AKT signaling and lung tumorigenesis by PIERCE1 ablation in KRAS-mutant non-small cell lung cancer ENSG00000128272 ENSG00000101255 ENSG00000160345 PMC10854812__F5 Function of CD133 protein ENSG00000010810 PMC2795248__F3 Anti-inflammatory effects of EPAC in VECs ENSG00000163914 ENSG00000168610 PMC5980113__F6 Role of MICAL1 in breast cancer cell proliferation ENSG00000135446 ENSG00000168036 ENSG00000135596 PMC3777479__F2 Niclosamide targets the Wnt/Beta-catenin, Notch, and mTORC1 pathways ENSG00000134982 ENSG00000169047 ENSG00000168036 PMC7265137__F3 Simplified picture illustrating some examples of how microorganisms promote the cancer ENSG00000125538 ENSG00000168036 ENSG00000168610 PMC4732855__F5 MAPK signaling pathway, determined using the Kyoto Encyclopedia of Genes and Genomes database ENSG00000138308 ENSG00000066468 ENSG00000115008 ENSG00000101751 ENSG00000170458 ENSG00000276870 ENSG00000198517 ENSG00000142733 ENSG00000130159 ENSG00000146648 ENSG00000026103 PMC10854812__F8 Models of both non-receptor tyrosine kinase- (NRTKs) and receptor tyrosine kinase-mediated signaling pathways in tumor progression and drug resistance ENSG00000157764 ENSG00000010810 ENSG00000155792 ENSG00000168610 PMC10854812__F9 Downstream effectors of RTK-mediated pathways and their biological consequences ENSG00000157764 ENSG00000118515 ENSG00000155792 ENSG00000171791 PMC9687113__F2 DNA Damage and Repair in Idiopathic Pulmonary Fibrosis ENSG00000105486 ENSG00000132781 ENSG00000132646 ENSG00000095002 ENSG00000136936 ENSG00000138385 ENSG00000122512 PMC3876931__F10 Differential regulation of the REGG–proteasome pathway by p53/TGFB signalling and mutant p53 in cancer cells ENSG00000169375 PMC11929932__F2 Immunomodulation on tumor immune microenvironment in acquired targeted therapy resistance and implication for immunotherapy resistance ENSG00000177575 ENSG00000135446 ENSG00000126353 ENSG00000145113 PMC4685960__F3 Endosomal Toll-like Receptors in Clinically Overt and Silent Autoimmunity ENSG00000115415 ENSG00000116747 PMC7464802__F3 MOMP-induced signaling activation in tumor cells ENSG00000164430 ENSG00000125538 ENSG00000110218 PMC3332287__F2 Wnt signaling pathway participated in the activation of hepatic stellate cells ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000100387 ENSG00000134982 ENSG00000147869 ENSG00000113558 ENSG00000115718 PMC3734089__F1 Macrophages in pancreatic cancer initiation and progression ENSG00000125398 ENSG00000148926 ENSG00000168610 PMC11496054__F1 CGAS–STING pathway of cytosolic DNA sensing ENSG00000183735 ENSG00000164430 PMC7080988__F2 Computational Model of the Endothelial to Mesenchymal Transition ENSG00000137834 ENSG00000138795 ENSG00000154764 ENSG00000169554 ENSG00000112715 ENSG00000168610 ENSG00000151702 ENSG00000170365 ENSG00000124216 ENSG00000198435 ENSG00000128917 ENSG00000122691 ENSG00000019549 ENSG00000179348 PMC6452569__F8 Parturition-specific signaling networks constructed using shortest paths and differential expression data ENSG00000070087 ENSG00000105835 ENSG00000002330 ENSG00000291971 ENSG00000050748 ENSG00000116791 ENSG00000205362 ENSG00000164305 ENSG00000136286 ENSG00000105894 ENSG00000078967 ENSG00000245848 ENSG00000134086 ENSG00000011422 ENSG00000082175 ENSG00000291814 ENSG00000183943 ENSG00000136997 ENSG00000099985 ENSG00000125148 ENSG00000175793 ENSG00000143164 ENSG00000173039 ENSG00000137193 ENSG00000005243 ENSG00000076555 ENSG00000127191 ENSG00000161960 ENSG00000123685 ENSG00000066136 ENSG00000174059 ENSG00000198355 PMC4835676__F5 An integrated model of the TLR signaling pathway modulated by the multifurcating motif of poeModules M14-M18 ENSG00000171855 ENSG00000188379 ENSG00000162496 ENSG00000150455 ENSG00000099942 ENSG00000166068 ENSG00000076108 ENSG00000177426 ENSG00000183735 ENSG00000198853 ENSG00000144802 ENSG00000038427 ENSG00000057704 ENSG00000157625 ENSG00000109320 ENSG00000140968 ENSG00000162924 ENSG00000276561 ENSG00000172183 ENSG00000117036 ENSG00000067066 ENSG00000115415 ENSG00000153048 ENSG00000026751 ENSG00000172936 ENSG00000131323 ENSG00000175104 PMC11496054__F2 CGAS-STING signaling in female reproductive system diseases ENSG00000118369 ENSG00000183735 ENSG00000164430 ENSG00000171720 ENSG00000143379 ENSG00000177084 ENSG00000130726 PMC8065059__F4 Metabolic capabilities among distinct lineages within the Brockarchaeota phylum ENSG00000102977 PMC8506768__F4 Bioinformatic analysis of differentially expressed genes and pathways in idiopathic pulmonary fibrosis ENSG00000065675 ENSG00000291603 ENSG00000282905 ENSG00000138798 ENSG00000108443 ENSG00000150455 ENSG00000121879 ENSG00000179295 ENSG00000175634 ENSG00000168062 ENSG00000213658 ENSG00000136869 ENSG00000124181 ENSG00000104365 ENSG00000100906 ENSG00000198851 ENSG00000269335 ENSG00000173039 ENSG00000027697 ENSG00000213341 ENSG00000127666 ENSG00000120910 ENSG00000123685 ENSG00000221823 ENSG00000115415 ENSG00000177606 ENSG00000070770 ENSG00000172936 ENSG00000131196 PMC3516830__F2 Interaction loop between the EGFR signaling pathway and miR-221/222 expression in the modulation of cellular processes ENSG00000100234 ENSG00000169554 ENSG00000002330 ENSG00000198793 ENSG00000104447 ENSG00000146648 PMC3070952__F1 Essential features of the PERK signaling temporal delay circuit ENSG00000128272 ENSG00000144895 ENSG00000162772 PMC10869077__F9 TNF signaling pathway ENSG00000171855 ENSG00000156735 ENSG00000110330 ENSG00000167207 ENSG00000165197 ENSG00000102871 ENSG00000124875 ENSG00000121879 ENSG00000164305 ENSG00000172216 ENSG00000157227 ENSG00000149968 ENSG00000078747 ENSG00000056558 ENSG00000164400 ENSG00000128342 ENSG00000168404 ENSG00000247077 ENSG00000026103 ENSG00000104365 ENSG00000081041 ENSG00000100906 ENSG00000137275 ENSG00000109320 ENSG00000007908 ENSG00000213341 ENSG00000168040 ENSG00000125347 ENSG00000127191 ENSG00000073756 ENSG00000226275 ENSG00000108691 ENSG00000128272 ENSG00000118503 ENSG00000177606 ENSG00000164136 ENSG00000136848 ENSG00000184371 ENSG00000131323 ENSG00000100985 ENSG00000083799 ENSG00000162692 ENSG00000285379 ENSG00000115009 PMC7859322__F2 EMT-related lncRNA in the process of triple-negative breast cancer metastasis ENSG00000169554 ENSG00000137673 PMC7743012__F4 Activation of cancer‐related signaling pathways ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000129514 ENSG00000136869 ENSG00000128602 PMC9315613__F3 Phytochemicals as Regulators of Tumor Glycolysis and Hypoxia Signaling Pathways: Evidence from In Vitro Studies ENSG00000198793 PMC2945668__F1 TLR7/9 Signaling pathway leading to the production of proinflammatory cytokines and type I IFN ENSG00000239732 ENSG00000172936 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC4123083__F8 The miR-203-mediated regulation network for skeletal muscle cell proliferation and differentiation ENSG00000283780 ENSG00000074181 ENSG00000081189 PMC9543876__F5 Pathway analysis using GRB2, a significantly connected and downregulated protein as the focus ENSG00000157404 ENSG00000033327 ENSG00000141441 ENSG00000213658 ENSG00000078747 ENSG00000015285 ENSG00000047936 ENSG00000111816 ENSG00000160691 ENSG00000154237 PMC6296821__F1 Ex vivo Transposon-Mediated Genetic Screens for Cancer Gene Discovery ENSG00000292332 PMC5005393__F1 Demonstration of how gene ontology annotations lead to understanding of biological networks ENSG00000157184 ENSG00000167114 ENSG00000115361 PMC2042021__F6 Contrasting Infection Strategies in Generalist and Specialist Wasp Parasitoids of Drosophila melanogaster ENSG00000166402 ENSG00000291791 ENSG00000172936 ENSG00000127191 PMC9688210__F1 Targeting TET2 as a Therapeutic Approach for Angioimmunoblastic T Cell Lymphoma ENSG00000150907 ENSG00000198793 PMC2958340__F3 Canonical Wnt/Beta-catenin signaling ENSG00000087095 ENSG00000168036 PMC10341274__F2 Contrasting roles of AGRP and POMC neurons in glucose and lipid homeostasis ENSG00000198576 ENSG00000115138 ENSG00000121853 PMC9496564__F2 Co-Stimulatory Receptor Signaling in CAR-T Cells ENSG00000213658 ENSG00000198793 ENSG00000056558 ENSG00000131323 ENSG00000124181 ENSG00000127191 PMC4322984__F9 Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/Beta-catenin pathway ENSG00000168036 PMC6365103__F1 Copper distribution pathways in a generalized mammalian cell ENSG00000173992 ENSG00000123191 ENSG00000177556 ENSG00000115107 PMC2134904__F7 Schematic representation of the effects of RhoA/ROCK signaling pathway inhibition on membrane FasL expression and lymphocytes apoptosis ENSG00000026103 PMC10312929__F8 Wnt signaling pathway ENSG00000087095 ENSG00000095739 ENSG00000134982 ENSG00000167941 ENSG00000196470 ENSG00000185269 PMC12139977__F6 Intersecting network analysis reveals interactions among genes involved in insulin secretion, cell cycle, and ER stress pathways ENSG00000160789 ENSG00000130522 ENSG00000132824 ENSG00000166402 ENSG00000101447 ENSG00000073111 ENSG00000145386 ENSG00000166851 ENSG00000115290 ENSG00000140534 ENSG00000093009 ENSG00000138778 ENSG00000138190 ENSG00000089685 ENSG00000176406 ENSG00000284290 ENSG00000130222 ENSG00000100219 ENSG00000076382 ENSG00000176165 ENSG00000071539 ENSG00000171320 ENSG00000277909 ENSG00000106803 ENSG00000101057 ENSG00000100526 ENSG00000132639 ENSG00000117399 ENSG00000016082 ENSG00000276043 ENSG00000117724 ENSG00000145604 ENSG00000198901 ENSG00000111602 ENSG00000111665 ENSG00000143476 ENSG00000171848 ENSG00000138161 ENSG00000166603 ENSG00000116661 ENSG00000138180 PMC7346528__F1 Hedgehog signaling pathway ENSG00000157540 ENSG00000106571 ENSG00000117425 ENSG00000166813 ENSG00000164690 ENSG00000163501 PMC3770777__F5 Schematic description of the metabolic network proposed to link DFMO-mediated inhibition of polyamine synthesis to observed perturbations in the methionine cycle, trans-sulfuration pathway, purine synthesis/salvage and de novo thymidine production ENSG00000284320 ENSG00000136371 PMC1857308__F9 The formation of peripheral myelin protein 22 aggregates is hindered by the enhancement of autophagy and expression of cytoplasmic chaperones ENSG00000198793 PMC9456457__F1 Insulin Receptor Substrate Proteins in Bronchopulmonary Dysplasia and Asthma: New Potential Perspectives ENSG00000198793 PMC3366885__F1 Signaling pathways involved in head and neck cancer ENSG00000002330 ENSG00000065361 ENSG00000136997 ENSG00000185591 ENSG00000168610 ENSG00000146648 PMC5433721__F6 An integrative analysis of tissue-specific transcriptomic and metabolomic responses to short-term dietary methionine restriction in mice ENSG00000169021 ENSG00000127540 ENSG00000147684 ENSG00000140740 ENSG00000073578 ENSG00000130414 ENSG00000138495 ENSG00000004779 PMC5518133__F2 Regulatory mechanisms of WBP2 in breast cancer ENSG00000132471 ENSG00000168036 ENSG00000146648 PMC7824603__F1 An integrated model of the molecular pathway underlying light-mediated seed germination ENSG00000140451 ENSG00000173402 PMC5884799__F7 MS TLR signalling pathway ENSG00000108691 ENSG00000125538 ENSG00000228083 ENSG00000173039 ENSG00000105656 ENSG00000168610 ENSG00000127948 ENSG00000062485 PMC5884799__F8 Multiple sclerosis pathway ENSG00000151490 ENSG00000111537 ENSG00000130164 PMC3893124__F1 Current and Future Therapies for Hepatitis C Virus Infection ENSG00000130164 ENSG00000073060 ENSG00000110651 ENSG00000146648 PMC11313706__F6 Regulatory mechanism of bone injuries induced by fluoride ENSG00000171791 ENSG00000100985 ENSG00000108821 ENSG00000077782 PMC5915419__F1 Molecular association of Wnt, MITF, TYR, and DCT ENSG00000168036 ENSG00000080166 PMC3492208__F3 Principal IFN-Alpha-modulated canonical pathway in MT-4 cells ENSG00000068079 ENSG00000159224 ENSG00000213928 ENSG00000111537 ENSG00000115415 ENSG00000033800 ENSG00000125347 ENSG00000230034 PMC5743859__F4 Nucleotide-binding oligomerization domain 1 and gastrointestinal disorders ENSG00000131323 ENSG00000106100 ENSG00000168610 ENSG00000276561 PMC1994616__F1 New molecularly targeted therapies for lung cancer ENSG00000157764 ENSG00000138798 ENSG00000146648 PMC9846474__F6 Unraveling the links between neurodegeneration and Epstein-Barr virus-mediated cell cycle dysregulation ENSG00000149311 ENSG00000175054 ENSG00000178999 ENSG00000135446 ENSG00000105810 PMC1994616__F2 New molecularly targeted therapies for lung cancer ENSG00000134982 ENSG00000128602 ENSG00000137845 PMC5362636__F2 Possible interplay between insulin-like growth factor (IGF)-1 and vascular endothelial growth factor (VEGF) receptor signaling pathways ENSG00000168036 ENSG00000174059 PMC7020744__F14 Role of RKI-1447 in liver cells and the TLR4/TBK1/IRF3 signaling pathway ENSG00000183735 ENSG00000136869 ENSG00000067900 PMC3845098__F1 N-glycoprotein biosynthesis in mammals ENSG00000101901 ENSG00000000419 ENSG00000139133 ENSG00000033011 ENSG00000172269 ENSG00000159063 ENSG00000088035 ENSG00000120697 ENSG00000214160 ENSG00000136908 PMC3824607__F3 Crosstalk in TNFR1 signaling ENSG00000102871 ENSG00000099860 ENSG00000168040 ENSG00000127191 PMC3824607__F1 TNFAlpha-mediated transient IKK activation pathways ENSG00000102871 ENSG00000127191 PMC1904333__F2 Hepcidin regulation: ironing out the details ENSG00000010704 ENSG00000106327 ENSG00000105697 ENSG00000168610 PMC5029683__F8 cRGD inhibits vasculogenic mimicry formation by down-regulating uPA expression and reducing EMT in ovarian cancer ENSG00000087245 ENSG00000170558 ENSG00000198793 PMC8844459__F1 Application of Animal Models in Interpreting Dry Eye Disease PMC12133868__F2 MAPK signaling pathway ENSG00000002330 ENSG00000157764 ENSG00000198793 PMC8968959__F1 Epidermal Growth Factor Pathway in the Age-Related Decline of Oligodendrocyte Regeneration ENSG00000110395 ENSG00000138798 PMC12133868__F3 Application and recent advances in conventional biomarkers for the prognosis of papillary thyroid carcinoma ENSG00000157764 ENSG00000136997 ENSG00000164362 PMC2764635__F3 New model of EGF activated ERK pathway: This is a schematic of our new model of the EGF activated ERK pathway which was developed from the original EGF model ENSG00000138798 ENSG00000146648 PMC6361568__F7 Cullin‐3 (CUL3) and KCTD10 regulate cell proliferation in SKBR‐3 cells ENSG00000143878 ENSG00000138798 ENSG00000110906 ENSG00000146648 PMC7182067__F1 The Regulation of Coagulation and Thrombosis ENSG00000281244 ENSG00000092439 ENSG00000110799 ENSG00000006451 ENSG00000144118 ENSG00000189403 PMC2764635__F1 The EGF activated ERK pathway: This is a schematic of the EGF activated ERK pathway beginning at the level of EGF binding to EGFR and finishing at the level of ERK; see the text for more details on the features and functions of the pathway ENSG00000138798 ENSG00000146648 PMC6909948__F4 cAMP can regulate multidrug-resistance in lung cancer through the regulation of plenty of downstream effectors, which is participating in the cAMP signaling pathway such as the classical PKA and CREB or some other useful effectors ENSG00000149311 ENSG00000168036 ENSG00000001626 ENSG00000077463 PMC3681194__F1 Genes with mutations that cause monogenic, severe T-cell immunodeficiency in humans can be intrinsic to the thymic epithelium or to T cells ENSG00000064490 ENSG00000143390 ENSG00000291603 ENSG00000196839 ENSG00000088305 ENSG00000232326 ENSG00000231925 ENSG00000105639 ENSG00000175097 ENSG00000135899 ENSG00000149311 ENSG00000110395 ENSG00000133111 PMC2764635__F7 Experimental results of Rap1 pathway knockout from Falco et al PMC2764635__F8 Comparison of growth factor receptor signalling: This figure shows a comparison of ERK signalling from the EGF and Insulin receptors ENSG00000138798 ENSG00000172005 ENSG00000146648 PMC4782155__F3 miR-146a-5p and miR-155-5p mechanism of action under normal conditions and early stages of inflammation (, , ) ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC4367534__F2 Regulators of HR repair as potential therapeutic targets ENSG00000169047 ENSG00000166851 ENSG00000147274 ENSG00000139618 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000197299 ENSG00000051180 ENSG00000173846 ENSG00000096401 ENSG00000146648 ENSG00000140443 PMC6131304__F3 PCV2-induced apoptosis ENSG00000128272 ENSG00000144895 ENSG00000026103 PMC4367534__F1 DNA double strand break (DSBs) repair ENSG00000012048 ENSG00000138346 ENSG00000132383 ENSG00000197299 ENSG00000051180 ENSG00000139618 PMC8346253__F1 Distinct Signaling Pathways Distinguish in vivo From in vitro Growth in Murine Ovarian Follicle Activation and Maturation ENSG00000198793 PMC7773602__F1 Autophagy and endolysosomal trafficking at the synapse ENSG00000142192 ENSG00000167964 ENSG00000111737 PMC2133163__F6 Anchorage-dependent cell growth ENSG00000177606 PMC3643575__F4 Arachidonic acid metabolism pathway where the differential genes and metabolites of colorectal cancer were annotated ENSG00000096088 ENSG00000128342 ENSG00000102977 PMC321455__F9 A model depicting the relationship between the p19Arf-p53 tumor suppressor pathway and the Rho GTPase signaling module in the regulation of cell proliferation and transformation ENSG00000124102 ENSG00000070831 PMC3561661__F1 Activation and function of PI3K/Akt signaling in CD8 T cell ENSG00000138795 ENSG00000134982 ENSG00000136997 ENSG00000127528 ENSG00000168036 ENSG00000168685 PMC7093717__F8 Schematic diagram depicting how luteolin inhibits airway allergic responses ENSG00000107485 ENSG00000105639 PMC7044323__F8 Gene expression profiles of p53 signaling pathway (hsa04115) in the bryostatin treated CD4+ T cells ENSG00000149311 ENSG00000175054 ENSG00000078900 ENSG00000136997 ENSG00000112378 ENSG00000177519 PMC8826420__F7 Proposed molecular mechanisms of ANGPTL7 in CLAN formation in TM cells ENSG00000185591 ENSG00000171819 PMC6376273__F2 The pathogen‐derived molecules employed to evade the intracellular DNA sensing pathway ENSG00000183735 ENSG00000164430 ENSG00000163568 ENSG00000163565 PMC9166676__F4 Chemoresistance in cancer stem cells ENSG00000070831 ENSG00000050165 ENSG00000103222 ENSG00000168487 ENSG00000168036 ENSG00000118777 PMC4741068__F2 Reconstruction of the insulin/insulin-like growth factor 1 (IGF1)-like signalling (IIS) pathway of Haemonchus contortus PMC5744163__F1 Three types of autophagy and regulatory mechanisms ENSG00000177169 ENSG00000110497 ENSG00000198382 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000171791 ENSG00000145782 ENSG00000057663 PMC8071872__F5 Lack of Cell Cycle Inhibitor p21 and Low CD4+ T Cell Suppression in Newborns After Exposure to IFNB ENSG00000213928 ENSG00000115415 PMC11211608__F2 Understanding copy number variations through their genes: a molecular view on 16p11.2 deletion and duplication syndromes ENSG00000149930 ENSG00000174943 PMC9550700__F7 Contribution of the Immune Response in the Ileum to the Development of Diarrhoea caused by Helminth Infection: Studies with the Sheep Model ENSG00000115008 ENSG00000167207 ENSG00000105329 ENSG00000134982 ENSG00000162600 ENSG00000027697 ENSG00000103522 ENSG00000049768 ENSG00000168610 ENSG00000069667 ENSG00000115607 ENSG00000162594 ENSG00000150782 ENSG00000111537 ENSG00000125538 ENSG00000107485 ENSG00000073861 ENSG00000162892 PMC9550700__F8 Contribution of the Immune Response in the Ileum to the Development of Diarrhoea caused by Helminth Infection: Studies with the Sheep Model ENSG00000099985 ENSG00000054967 PMC12108277__F5 Summary schematic diagram of the mechanism by which miR-129a-3p negatively regulates the inflammatory response to G ENSG00000172936 ENSG00000136869 PMC8998186__F3 Recycling and Reshaping—E3 Ligases and DUBs in the Initiation of T Cell Receptor-Mediated Signaling and Response ENSG00000152484 ENSG00000264522 ENSG00000291603 ENSG00000078747 ENSG00000010810 ENSG00000083799 PMC8998186__F4 Recycling and Reshaping—E3 Ligases and DUBs in the Initiation of T Cell Receptor-Mediated Signaling and Response ENSG00000135655 ENSG00000152484 ENSG00000078747 ENSG00000175104 PMC6315101__F1 Central metabolism in the S ENSG00000075856 ENSG00000146701 ENSG00000062485 PMC8490443__F4 BMP7 reduces the fibrocartilage chondrocyte phenotype ENSG00000087245 ENSG00000157227 ENSG00000162551 ENSG00000196154 ENSG00000103888 ENSG00000108821 ENSG00000183160 ENSG00000122194 PMC6065472__F7 Enriched pathways for radix tetrastigma hemsleyani flavonoid treated lung cancer cells ENSG00000087095 ENSG00000172680 ENSG00000002330 ENSG00000291971 ENSG00000130522 ENSG00000138798 ENSG00000113070 ENSG00000198793 ENSG00000158458 ENSG00000130159 ENSG00000127191 ENSG00000081189 ENSG00000169752 ENSG00000169291 ENSG00000110395 ENSG00000170458 ENSG00000136997 ENSG00000196712 ENSG00000026103 PMC8800342__F1 Human epidermal growth factor receptor 2 (HER2)-specific chimeric antigen receptor (CAR) for tumor immunotherapy; recent progress ENSG00000002330 ENSG00000177606 ENSG00000136997 PMC5494993__F6 Discovery of extremely halophilic, methyl-reducing euryarchaea provides insights into the evolutionary origin of methanogenesis ENSG00000182511 ENSG00000156110 ENSG00000153574 ENSG00000115718 ENSG00000127948 PMC2575803__F1 Most prominently involved biological pathways in OSCC ENSG00000105397 ENSG00000115415 ENSG00000095321 ENSG00000198793 ENSG00000033800 ENSG00000137193 PMC10971338__F1 General schemes of the NAD+ metabolic pathway ENSG00000105835 ENSG00000123572 ENSG00000278488 PMC4379025__F12 Telomerase Inhibition Decreases Alpha-Fetoprotein Expression and Secretion by Hepatocellular Carcinoma Cell Lines: In Vitro and In Vivo Study ENSG00000198793 ENSG00000081051 ENSG00000168610 PMC8348973__F2 Probiotic-Induced Tolerogenic Dendritic Cells: A Novel Therapy for Inflammatory Bowel Disease? ENSG00000187554 PMC7643645__F6 Potential working model for the suppression of Asperolide A in bone metastatic breast cancer ENSG00000198793 ENSG00000131196 ENSG00000143387 PMC7393488__F7 LEF1 mediates osteoarthritis progression through circRNF121/miR-665/MYD88 axis via NF-кB signaling pathway ENSG00000138795 ENSG00000172936 ENSG00000137522 PMC9311450__F1 Strategies to Reduce the On‐Target Platelet Toxicity of Bcl‐xL Inhibitors: PROTACs, SNIPERs and Prodrug‐Based Approaches ENSG00000002330 PMC3922885__F7 RhoC Regulates Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma by Overexpressing IL-6 and Phosphorylation of STAT3 ENSG00000168610 PMC4739416__F1 JAK-STAT signaling contributes to the pathogenesis of MPNs ENSG00000198793 PMC10963420__F1 Mechanism of astrocyte regulation of Lcn-2 ENSG00000148346 ENSG00000144895 ENSG00000100906 ENSG00000086991 ENSG00000064300 PMC8507001__F6 Baicalin promotes chondrocyte viability and the synthesis of extracellular matrix through TGFB/Smad3 pathway in chondrocytes ENSG00000154736 ENSG00000125398 PMC11881707__F3 Interaction mechanism between intestinal flora and cAMP-PKA signaling pathway in neurological diseases ENSG00000129167 PMC3876023__F1 Suppression of regulatory B cells identified in human and animal ENSG00000186716 ENSG00000049768 PMC2684867__F1 VHL Loss of Function and Its Impact on Oncogenic Signaling Networks in Clear Cell Renal Cell Carcinoma ENSG00000019991 ENSG00000281324 ENSG00000162337 PMC4149909__F2 Gaps in conventional treatment of heart failure include deranged Beta-AR signaling, distorted Ca2+ cycling with depletion of SR Ca2+ levels, diastolic dysfunction, and cell death ENSG00000002330 ENSG00000198626 ENSG00000084774 PMC4944499__F7 CRT-knockdown correlates with the modulation of p53 and MAPK pathways ENSG00000149311 ENSG00000206075 PMC10493031__F3 Schematic illustration of the CRC-derived exosome mechanisms for CRC metastasis ENSG00000019991 ENSG00000161921 ENSG00000291971 ENSG00000159388 ENSG00000026508 ENSG00000110651 ENSG00000010278 ENSG00000135404 ENSG00000121966 PMC10493031__F5 Schematic illustration of key molecular signaling pathways in metastasis ENSG00000123364 ENSG00000019991 ENSG00000026508 ENSG00000168036 ENSG00000183742 ENSG00000292194 ENSG00000166948 ENSG00000146648 ENSG00000121966 ENSG00000198910 ENSG00000225950 ENSG00000109670 PMC11247318__F1 Action in lymphoma ENSG00000177455 ENSG00000111537 ENSG00000010671 PMC12082737__F3 Canonical wnt signalling pathway (Kharaishvili et al ENSG00000156076 ENSG00000134982 ENSG00000168036 PMC2976306__F7 Changes in gene expression in central carbon metabolism (A) and ergosterol synthesis (B) ENSG00000157554 ENSG00000074800 ENSG00000090863 ENSG00000146701 ENSG00000100029 PMC6605468__F5 Schematic model of morphogenic gradients controlling striatal development and involved in abnormal neurogenesis in Rarb−/− mice ENSG00000184845 ENSG00000139352 ENSG00000143995 PMC10930964__F1 Discrete Mechanistic Target of Rapamycin Signaling Pathways, Stem Cells, and Therapeutic Targets ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC6887951__F4 FGFR pathway and dysregulation in cancer PMC5760356__F1 Kegg PI3K/Akt‐Signaling pathway with highlighted dysregulated mRNA and their associated seed‐region matched miRNA ENSG00000159921 ENSG00000103479 ENSG00000002330 ENSG00000261857 ENSG00000186716 ENSG00000198793 ENSG00000134121 PMC5102338__F6 Diagrammatic representation of possible mechanistic pathway for the induction of EGID ENSG00000163235 PMC8502875__F5 Soluble Epoxide Hydrolase Inhibitors Regulate Ischemic Arrhythmia by Targeting MicroRNA-1 ENSG00000124102 PMC7567953__F1 Sphingosine-1-phosphate (S1P) production and S1P/S1PR signaling pathways ENSG00000063176 ENSG00000163914 ENSG00000170989 ENSG00000180739 ENSG00000213694 ENSG00000125910 ENSG00000267534 ENSG00000183018 PMC7567953__F2 Dental regenerative therapy targeting sphingosine-1-phosphate (S1P) signaling pathway in endodontics ENSG00000170365 ENSG00000168036 ENSG00000170989 ENSG00000267534 PMC7882108__F8 VD3 ameliorated NM‐induced cutaneous inflammation by inactivating the NLRP3 inflammasome through the SIRT3–SOD2–mtROS signaling pathway ENSG00000162711 ENSG00000142082 PMC7567953__F3 Dental regenerative therapy targeting sphingosine-1-phosphate (S1P) signaling pathway in endodontics ENSG00000162337 ENSG00000168036 ENSG00000267534 PMC5661282__F9 Role of glycolysis in NPC self-renewal ENSG00000125931 ENSG00000102678 PMC7688453__F1 ERK and AKT pathway on lymphangiogenesis ENSG00000105808 ENSG00000136997 ENSG00000117707 ENSG00000112715 ENSG00000123268 ENSG00000196712 ENSG00000150630 PMC12095467__F8 125I particles inhibit the progression of cervical cancer by up-regulating the HSF1/PU ENSG00000141867 ENSG00000284774 ENSG00000128272 ENSG00000066336 ENSG00000100219 PMC9691885__F2 Determinants regulating Toxoplasma gondii bradyzoite development ENSG00000111537 ENSG00000171720 PMC9691885__F1 Determinants regulating Toxoplasma gondii bradyzoite development ENSG00000074800 ENSG00000170373 PMC7649967__F2 Biglycan in the Skeleton ENSG00000170365 ENSG00000170909 ENSG00000281324 ENSG00000162337 ENSG00000004948 ENSG00000167941 ENSG00000198742 ENSG00000131196 PMC7662933__F3 ErbB receptors and their signaling pathways ENSG00000065361 ENSG00000291971 ENSG00000010810 ENSG00000198793 ENSG00000158458 ENSG00000169752 ENSG00000178568 PMC9560885__F2 Race to develop oral SERDs and other novel estrogen receptor inhibitors: recent clinical trial results and impact on treatment options ENSG00000135446 ENSG00000105810 ENSG00000146648 PMC133602__F6 The yeast glyoxylate bypass pathway and its possible connection with other predicted changes ENSG00000178741 PMC7169117__F6 Schematic illustration of the major KSHV factors and corresponding targets, by which KSHV modulates the TGF‐B signaling pathway ENSG00000137801 PMC8826489__F1 Circadian rhythms of 11-oxygenated C19 steroids and Δ5-steroid sulfates in healthy men ENSG00000203859 ENSG00000176387 PMC7169117__F7 Schematic illustration of the major HTLV‐1 proteins and corresponding targets, by which HTLV‐1 modulates the TGF‐B signaling pathway ENSG00000130656 ENSG00000049768 PMC7169117__F8 Schematic illustration of the major SARS‐CoV proteins and corresponding targets, by which the virus modulates the TGF‐B signaling pathway ENSG00000168610 PMC3122057__F8 Proposed schematic of the roles of NIK and SMG1 in sensitive versus resistant cells in response to SMC and TNFA treatment ENSG00000168040 ENSG00000157106 ENSG00000127191 PMC7169117__F2 Schematic illustration of the major HCV proteins and corresponding targets, by which HCV modulates the TGF‐B signaling pathway PMC6526582__F1 Schematic representation of the three candidate genes and the four tag SNPs selected for this study in the IL-23 signalling pathway (SNPs rs3212227 and rs6887695 in IL-12B, SNP rs7857730 in JAK2, and SNP rs2293152 in STAT3) ENSG00000096996 ENSG00000105397 ENSG00000168610 PMC5607814__F1 AMIGO3 and LINGO-1 signaling in neurons.Both AMIGO3 and LINGO-1 are able to form a complex with NgR1 and P75/TROY (Mi et al., 2004; Ahmed et al., 2013) ENSG00000163914 ENSG00000169783 PMC7169117__F4 Schematic illustration of the major HPV proteins and corresponding targets, by which HPV modulates the TGF‐B signaling pathway ENSG00000185591 PMC5607814__F2 Mechanisms of action for LINGO-1 and speculative AMIGO3 signaling in oligodendroglia.(A) LINGO-1 is able to bind to ErbB2 and prevent its translocation to the lipid rafts on oligodendroglial membranes ENSG00000198793 ENSG00000169783 ENSG00000146648 PMC7169117__F5 Schematic illustration of the major EBV proteins and corresponding targets, by which EBV modulates the TGF‐B signaling pathway ENSG00000162772 ENSG00000125968 PMC6015663__F4 SHP2 plays a key role in NSC proliferation, differentiation, and migration ENSG00000138798 ENSG00000168610 ENSG00000121966 PMC8744084__F2 Molecular regulation of brain metabolism underlying circadian epilepsy ENSG00000105835 ENSG00000165030 ENSG00000105516 ENSG00000108924 ENSG00000198793 ENSG00000132326 ENSG00000167074 ENSG00000096717 ENSG00000069667 PMC3461607__F1 LPS/TLR-4 signaling pathway.Notes: LPS is delivered to CD14 by LBP, which in turn transfers LPS to TLR-4 ENSG00000174125 ENSG00000170458 ENSG00000187554 ENSG00000125538 ENSG00000172936 PMC11792562__F4 Pathway map of differentially expressed genes involved in cytidine synthesis across the comparison groups: A glycolytic pathway; B TCA cycle; C cytidine synthesis pathways ENSG00000143252 ENSG00000073578 ENSG00000117118 PMC11792562__F5 Pathway diagrams of differential metabolites related to the cytidine synthesis pathway in the comparison groups: A glycolytic pathway; B TCA cycle; C cytidine synthesis pathways ENSG00000143252 ENSG00000073578 ENSG00000117118 PMC3434281__F6 Proposed model for attenuation of canonical TGFB SMAD and activation of non-canonical TGF-Beta-NFKB signaling pathways in HNSCC ENSG00000105329 PMC8199989__F2 HECT-Type E3 Ligase in the Development of Cardiac Disease ENSG00000281324 ENSG00000162337 ENSG00000089685 ENSG00000078747 ENSG00000168036 ENSG00000265972 ENSG00000077463 PMC8527165__F2 Immunosuppressive metabolites in tumoral immune evasion: redundancies, clinical efforts, and pathways forward ENSG00000164879 ENSG00000086730 ENSG00000106546 PMC8527165__F3 Immunosuppressive metabolites in tumoral immune evasion: redundancies, clinical efforts, and pathways forward ENSG00000106546 PMC8527165__F1 Immunosuppressive metabolites in tumoral immune evasion: redundancies, clinical efforts, and pathways forward ENSG00000151657 ENSG00000123454 ENSG00000168803 ENSG00000141744 ENSG00000005381 PMC6016890__F3 Mechanisms behind low levels of hepcidin in liver disease ENSG00000010704 ENSG00000106327 ENSG00000105697 PMC9268799__F5 Brevilin A Isolated from Centipeda minima Induces Apoptosis in Human Gastric Cancer Cells via an Extrinsic Apoptotic Signaling Pathway ENSG00000291971 ENSG00000164362 ENSG00000169032 ENSG00000145386 ENSG00000196396 PMC11592827__F13 Integrative Network Pharmacology, Molecular Docking, and Dynamics Simulations Reveal the Mechanisms of Cinnamomum tamala in Diabetic Nephropathy Treatment: An In Silico Study ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000104894 PMC9247875__F6 Prediction of Angiopoietin-like Protein 4-related Signaling Pathways in Cholangiocarcinoma Cells ENSG00000167772 ENSG00000198793 ENSG00000253729 PMC9268799__F2 Brevilin A Isolated from Centipeda minima Induces Apoptosis in Human Gastric Cancer Cells via an Extrinsic Apoptotic Signaling Pathway ENSG00000120915 ENSG00000291971 ENSG00000135446 ENSG00000163131 ENSG00000164362 ENSG00000123374 ENSG00000105810 ENSG00000169032 ENSG00000145386 ENSG00000196396 PMC11592827__F14 Integrative Network Pharmacology, Molecular Docking, and Dynamics Simulations Reveal the Mechanisms of Cinnamomum tamala in Diabetic Nephropathy Treatment: An In Silico Study ENSG00000157184 ENSG00000150991 ENSG00000167910 ENSG00000100979 ENSG00000165269 PMC11730944__F5 Upregulated and downregulated gene expression profiles within distinct pathways ENSG00000123999 ENSG00000104899 ENSG00000143185 ENSG00000137077 ENSG00000156574 ENSG00000128342 ENSG00000187266 ENSG00000150455 ENSG00000121966 PMC12021630__F10 Molecular mechanisms of PGRN in diabetic nephropathy ENSG00000177169 ENSG00000159399 PMC2806747__F1 TLR4 signaling pathway can be activated via GAG fragments requiring CD44 and MyD88 or through LPS, which requires MyD88, LBP, and CD14 ENSG00000170458 ENSG00000125538 ENSG00000026508 ENSG00000172936 PMC4391134__F7 Diagram of potential APOE4 -induced decrease in synapse-related proteins and disruption of NMDAR-mediated signaling, resulting in impaired learning and memory ENSG00000112367 ENSG00000143631 ENSG00000182263 PMC6630988__F2 Herpesviruses modulate the JAK-STAT pathway ENSG00000159128 ENSG00000213928 ENSG00000105397 ENSG00000185436 ENSG00000027697 ENSG00000125347 ENSG00000142166 PMC8741861__F7 Follicle stimulating hormone and its receptors in reproduction and in stem cells and cancer stem cells PMC8741861__F8 Follicle stimulating hormone and its receptors in reproduction and in stem cells and cancer stem cells ENSG00000150907 ENSG00000198793 PMC8741861__F5 Follicle stimulating hormone and its receptors in reproduction and in stem cells and cancer stem cells ENSG00000135446 ENSG00000146648 PMC7369546__F3 ClueGO plug-in, in terms of biological process and biochemical pathway process annotations, revealed biological terms which were associated with the 7 hub-bottlenecks (see ) ENSG00000163739 ENSG00000100985 PMC4933276__F10 The proposed T835M-UNC5C- and V642I-APP-induced neuronal death-signaling pathways ENSG00000142192 ENSG00000070831 ENSG00000122756 ENSG00000168610 ENSG00000131370 PMC8040300__F7 Molecular mechanisms underly GSS against brain injury in tMCAO rats ENSG00000125538 ENSG00000129226 PMC7463618__F3 Lipids in regulating NLRP3 inflammasome ENSG00000162711 ENSG00000135218 ENSG00000086991 ENSG00000169710 ENSG00000136869 ENSG00000175567 PMC7409684__F1 Pathological roles of ion channels and transporters in triple-negative breast cancer cells ENSG00000156026 ENSG00000001626 ENSG00000140443 PMC8660813__F9 Kinetin-induced death of Vicia faba ssp. minor root cortex cells ENSG00000151657 PMC5912903__F1 PRPP riboswitches and their regulatory network ENSG00000145321 ENSG00000137831 ENSG00000115271 ENSG00000185129 ENSG00000146676 PMC6020658__F3 Pathway mechanisms underlying CHMs improve lipid metabolism in liver cells ENSG00000138075 ENSG00000130164 ENSG00000108924 ENSG00000169174 ENSG00000026103 PMC3077584__F6 The effects of apoA-I on TNFA mRNA stabilization in LPS-stimulated macrophages ENSG00000125538 ENSG00000136869 ENSG00000168610 PMC11313175__F2 RNA methylation in the development of muscle and fat in livestock ENSG00000042832 ENSG00000099860 ENSG00000168610 ENSG00000081189 PMC10494518__F1 Insulin signaling pathway ENSG00000110395 ENSG00000169047 ENSG00000198793 PMC7169117__F1 TGF‐B signaling pathway PMC7520422__F9 Sphingosine-1-phosphate (S1P) acts in both S1PR dependent and independent pathways ENSG00000063176 ENSG00000137275 ENSG00000127191 PMC4183579__F3 Role of MicroRNA Modulation in the InterferonA/Ribavirin Suppression of HIV-1 In Vivo ENSG00000134321 ENSG00000196754 ENSG00000117228 ENSG00000187608 ENSG00000134574 ENSG00000143569 ENSG00000112378 ENSG00000035928 ENSG00000076003 ENSG00000140464 ENSG00000155363 ENSG00000183765 PMC5824490__F6 Emerging Roles for SIRT5 in Metabolism and Cancer ENSG00000154059 PMC3175712__F1 (A–C) Schematics of Wnt signaling components in the absence of a Wnt signal (A), the presence of a Wnt signal (B), and the presence of a Wnt signal blocked by the displacement of Tcf7l2 by dnTcf7l2 (C) ENSG00000134982 ENSG00000168036 ENSG00000105723 PMC8897435__F8 Model of this study ENSG00000164932 PMC8227515__F1 Emerging Role of Amino Acids of the Brain Microenvironment in the Process of Metastasis Formation ENSG00000284320 ENSG00000092621 PMC3218904__F1 Network pathway analysis of up-regulated genes in the gene category immune response ENSG00000172831 ENSG00000112559 ENSG00000077044 ENSG00000138185 ENSG00000287542 ENSG00000231925 ENSG00000121966 ENSG00000278788 ENSG00000129993 ENSG00000131398 ENSG00000102699 ENSG00000166523 ENSG00000239998 ENSG00000122121 ENSG00000108932 ENSG00000135392 PMC4718447__F1 Translational metabolomics in cancer research ENSG00000169710 ENSG00000159399 ENSG00000198586 PMC3218904__F2 Network pathway analysis of down-regulated genes in the gene category mitotic cell cycle ENSG00000172831 ENSG00000182481 ENSG00000137713 ENSG00000094880 ENSG00000137601 ENSG00000128951 ENSG00000060982 ENSG00000131153 ENSG00000087085 ENSG00000087586 ENSG00000146143 ENSG00000135476 ENSG00000230797 ENSG00000278788 ENSG00000112312 ENSG00000101868 ENSG00000153140 ENSG00000105497 ENSG00000148798 ENSG00000136997 ENSG00000112742 ENSG00000198478 ENSG00000121104 ENSG00000167112 ENSG00000101224 ENSG00000139618 ENSG00000117724 ENSG00000117650 ENSG00000109805 ENSG00000132646 ENSG00000171848 ENSG00000100479 ENSG00000004897 ENSG00000075218 ENSG00000095002 ENSG00000132341 ENSG00000149503 PMC3775856__F10 Tissue factor pathway inhibitor prevents airway obstruction, respiratory failure and death due to sulfur mustard analog inhalation ENSG00000003436 ENSG00000122194 PMC3026473__F2 Diabetic Cardiomyopathy: Mechanisms and Therapeutic Targets ENSG00000169047 PMC7369546__F4 ClueGO plug-in, in terms of biological process and biochemical pathway process annotations, revealed biological terms which were associated with the 7 hub-bottlenecks (see ) ENSG00000081041 ENSG00000163739 ENSG00000100985 PMC9561999__F6 Good, the Bad and the New about Uric Acid in Cancer ENSG00000198793 PMC3715494__F2 A Lover and a Fighter: The Genome Sequence of an Entomopathogenic Nematode Heterorhabditis bacteriophora ENSG00000170967 ENSG00000118515 PMC9561999__F4 Good, the Bad and the New about Uric Acid in Cancer ENSG00000113161 ENSG00000026103 PMC8396560__F1 Macrophage Motility in Wound Healing Is Regulated by HIF-1A via S1P Signaling ENSG00000162711 ENSG00000108691 ENSG00000198793 ENSG00000121807 PMC2697061__F2 Endoplasmic reticulum stress in disorders of myelinating cells ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC9074313__F5 Functional roles of the circRNA/Wnt axis in cancer ENSG00000078747 ENSG00000168036 PMC9074313__F3 Functional roles of the circRNA/Wnt axis in cancer ENSG00000155011 ENSG00000168036 PMC5448626__F7 Possible schematic model of SNIPER(TACC3)‐induced death in cancer cells ENSG00000013810 ENSG00000134982 ENSG00000100219 PMC9074313__F1 Functional roles of the circRNA/Wnt axis in cancer ENSG00000100592 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC3166778__F1 PI3K signalling pathway: The phosphatidylinositol 3-kinase (PI3K) signalling pathway begins with PI3K activation by receptor tyrosine kinases after growth factors or insulin stimulation ENSG00000002330 PMC6477733__F3 Transcriptional reprogramming of the H-series strains H14, 20, 27, and 31 at 24 h post-induction of gene expression ENSG00000083857 ENSG00000172955 ENSG00000147526 ENSG00000128513 PMC8803618__F3 Microbiota in Gastrointestinal Cancer and Cancer Treatment: Chance or Curse? ENSG00000105329 ENSG00000163739 ENSG00000168036 ENSG00000168610 PMC8946661__F8A Systematic Review to Define the Multi-Faceted Role of Lysine Methyltransferase SETD7 in Cancer ENSG00000132109 ENSG00000198561 ENSG00000145386 ENSG00000230797 ENSG00000168646 ENSG00000145391 PMC4314529__F1 Mechanism of ICL repair in the FA pathway on collision of a replication fork with an ICL ENSG00000012048 ENSG00000188827 ENSG00000162607 ENSG00000276787 PMC5599801__F1 Modulating NAD + metabolism, from bench to bedside ENSG00000143799 ENSG00000123572 ENSG00000278488 PMC11084201__F18 Mechanisms of MPs’ impacts on the liver ENSG00000042832 ENSG00000154059 ENSG00000026103 PMC3034644__F2 Self-regulation in Xenopus dorsal-ventral patterning.The pathway consists of a network of BMP-interacting proteins PMC4795052__F4 Dysregulation of mTOR signaling pathway and mTOR in sleep phenotype of del 2q23.1 and SMS ENSG00000163435 ENSG00000198793 ENSG00000163914 ENSG00000164327 ENSG00000102172 PMC3134268__F1 Schematic representation of the influence of photoperiod on deiodinase enzyme gene expression in the hypothalamus ENSG00000165409 ENSG00000134200 PMC5923376__F2 Hippo signaling pathway ENSG00000126016 ENSG00000180667 ENSG00000069869 ENSG00000181788 ENSG00000078747 ENSG00000150457 ENSG00000131023 PMC6828744__F1 Long noncoding RNA: TRIMming the viral load ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000163568 ENSG00000163565 ENSG00000131323 ENSG00000121060 ENSG00000276561 ENSG00000164342 PMC9003189__F2 Amino Acid-Related Metabolic Signature in Obese Children and Adolescents ENSG00000155792 PMC8168947__F2 Mini-Review: PDPK1 (3-phosphoinositide dependent protein kinase-1), An Emerging Cancer Stem Cell Target ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000166851 ENSG00000128602 PMC4007928__F1 Key features of the phosphoinositide 3-kinase (PI3K) signaling pathway ENSG00000002330 PMC8247573__F1 Arbuscular Mycorrhiza-Mediated Regulation of Polyamines and Aquaporins During Abiotic Stress: Deep Insights on the Recondite Players PMC7814318__F1 Wnt pathway ENSG00000070831 ENSG00000134982 ENSG00000168036 PMC3725758__F2 Neurofibromatosis Type 2 Protein, NF2: An uncoventional cell cycle regulator ENSG00000186575 ENSG00000070831 ENSG00000198793 PMC8310495__F1 Genetic Determinants of Paget’s Disease of Bone ENSG00000243317 ENSG00000123240 ENSG00000143373 ENSG00000164935 ENSG00000083799 ENSG00000155561 ENSG00000175104 ENSG00000108518 ENSG00000140464 PMC8778376__F1 Microenvironmental Metabolites in the Intestine: Messengers between Health and Disease ENSG00000134982 ENSG00000168036 ENSG00000180902 ENSG00000070669 ENSG00000106546 PMC9623991__F2 Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer ENSG00000180210 ENSG00000129219 ENSG00000063176 ENSG00000165119 ENSG00000041982 ENSG00000070831 ENSG00000291971 ENSG00000168461 ENSG00000090924 ENSG00000165527 ENSG00000146648 PMC6156150__F7 Proposed network for AhR-Src-STAT3-IL-10 signaling pathway in inflammatory macrophages ENSG00000170458 ENSG00000291971 ENSG00000172936 ENSG00000136869 ENSG00000168610 ENSG00000106546 PMC9119763__F7 Blockage of Fibronectin 1 Ameliorates Myocardial Ischemia/Reperfusion Injury in Association with Activation of AMP-LKB1-AMPK Signaling Pathway ENSG00000116688 ENSG00000171109 PMC9623991__F6 Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer ENSG00000167323 ENSG00000293604 ENSG00000284254 ENSG00000072315 ENSG00000110218 ENSG00000168610 ENSG00000011347 PMC2789271__F1 Gene selection in the TGFß signaling pathway ENSG00000170365 ENSG00000137834 ENSG00000105329 PMC4727338__F2 Interaction between neurotrophins and VEGF ENSG00000198793 PMC3732412__F3 KEGG pathway map for genes in the three modules ENSG00000049323 ENSG00000137834 ENSG00000111537 ENSG00000100387 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000164093 ENSG00000137801 PMC3245719__F1 Bioenergetic regulation of cellular physiology and gene expression ENSG00000124102 ENSG00000096717 ENSG00000100294 PMC6674889__F9 The promotion of neuronal development by CD47 ENSG00000070831 ENSG00000291971 ENSG00000160293 PMC7022772__F6 KEGG proteasome pathway shows involvement of downregulated cytoplasmic ENSG00000111537 ENSG00000163902 ENSG00000198576 ENSG00000291973 ENSG00000132963 PMC6883840__F1 The pathway for synthesis of PLP in E ENSG00000185591 ENSG00000167182 PMC3119520__F7 Predicted d-galactose network in Y. pestis ENSG00000116096 PMC12108420__F12 GnRH signaling pathway involves multiple molecular interactions regulating gonadotropin gene expression and secretion ENSG00000109163 ENSG00000087245 ENSG00000070831 ENSG00000291971 ENSG00000138798 ENSG00000177606 ENSG00000145321 ENSG00000146648 PMC8265195__F3 Drug-drug-gene Interactions as Mediators of Adverse Drug Reactions to Diclofenac and Statins: A Case Report and Literature Review ENSG00000108242 ENSG00000138115 ENSG00000137204 ENSG00000197901 ENSG00000165841 ENSG00000168065 ENSG00000118777 ENSG00000023839 PMC3025764__F4 Metabolic regulation by FOXO1 in skeletal muscle ENSG00000135218 ENSG00000198793 PMC9649783__F7 MYBPC3 deficiency up-regulated NFKB/TGFB1/HIF-1A/aerobic glycolysis signaling cascade in cardiac fibroblasts, contributing to HCM myocardial fibrosis ENSG00000108691 ENSG00000125538 ENSG00000108821 PMC3910345__F3 Molecular regulation of hepcidin by iron and inflammation ENSG00000170365 ENSG00000010704 ENSG00000106327 ENSG00000168610 PMC8161522__F3 Multi-influential genetic interactions alter behaviour and cognition through six main biological cascades in Down syndrome mouse models ENSG00000157540 ENSG00000174576 ENSG00000143839 ENSG00000167900 PMC3893930__F2 Ewing’s Sarcoma: Overcoming the Therapeutic Plateau ENSG00000151702 ENSG00000198793 ENSG00000164327 ENSG00000140443 PMC11914587__F7 Autophagy in neuronal death ENSG00000183735 ENSG00000123240 ENSG00000284099 ENSG00000283741 ENSG00000147894 PMC11914587__F3 Interactome of the molecular systems architecture of the NMJ microenvironment involved in ALS pathogenesis ENSG00000188021 ENSG00000163914 ENSG00000075213 ENSG00000147894 PMC4581211__F8 Proposed model of role of RNase L in crosstalk between autophagy and apoptosis ENSG00000089127 ENSG00000171791 ENSG00000135828 PMC6814203__F2 STING pathway activation initiates the anti-tumor immune response ENSG00000123685 ENSG00000169245 ENSG00000138755 PMC6814203__F1 STING pathway signaling and regulation ENSG00000278718 ENSG00000106785 ENSG00000112343 ENSG00000119401 ENSG00000163568 ENSG00000163565 ENSG00000159461 ENSG00000186480 ENSG00000137699 ENSG00000169871 ENSG00000164104 ENSG00000198925 ENSG00000183735 ENSG00000164430 ENSG00000197594 ENSG00000189403 ENSG00000177169 ENSG00000146063 ENSG00000167323 ENSG00000159714 ENSG00000090432 ENSG00000163904 ENSG00000135912 ENSG00000170703 ENSG00000131323 ENSG00000173456 PMC8470786__F2 Interaction between microRNAs and the Wnt/Beta-Catenin Signaling Pathway in Osteoarthritis ENSG00000087095 ENSG00000125398 ENSG00000134982 ENSG00000168036 PMC10372241__F1 New insights into regulatory cell death and acute pancreatitis ENSG00000120868 ENSG00000168040 ENSG00000026103 PMC12189910__F8 Schematic figure depicting the potential role of LPS on endometrial receptivity in sheep ENSG00000259207 ENSG00000136869 ENSG00000128342 PMC8534127__F5 Novel Molecular Mechanism of Lenalidomide in Myeloid Malignancies Independent of Deletion of Chromosome 5q ENSG00000134460 ENSG00000159200 ENSG00000161405 ENSG00000137265 ENSG00000167986 ENSG00000139842 ENSG00000113851 PMC6592288__F5 Mutations of the MAPK/TSC/mTOR pathway characterize periventricular glioblastoma with epithelioid SEGA-like morphology–morphological and therapeutic implications ENSG00000135446 ENSG00000196712 PMC5423480__F3 Induction of an innate immune response to Ad-based vectors ENSG00000174125 ENSG00000213928 ENSG00000239732 ENSG00000167207 ENSG00000115415 ENSG00000172936 ENSG00000136869 PMC6221654__F5 Gene regulation network of 4 gene signature models ENSG00000064042 ENSG00000049768 ENSG00000196628 ENSG00000157557 ENSG00000245848 ENSG00000172216 ENSG00000186340 ENSG00000175832 ENSG00000136026 ENSG00000108821 ENSG00000179348 ENSG00000196712 ENSG00000100811 ENSG00000138449 ENSG00000169896 ENSG00000164941 ENSG00000138378 ENSG00000115415 ENSG00000177606 ENSG00000196092 ENSG00000136160 ENSG00000162692 ENSG00000128709 ENSG00000115155 ENSG00000131196 PMC4067122__F6 Schematic drawing of the Hippo pathway in human EC ENSG00000150457 PMC5070033__F1 Molecular signaling events of brain-derived neurotrophic factor-mitogen-activated protein kinase pathway and depression ENSG00000131096 PMC6482021__F2 Thyroid enlargement in patients with homozygous INSR mutation ENSG00000171105 PMC7327477__F7 Nucleotide depletion reveals the impaired ribosome biogenesis checkpoint as a barrier against DNA damage ENSG00000145604 PMC8067938__F1 Hippo signaling: bridging the gap between cancer and neurodegenerative disorders ENSG00000129474 ENSG00000113645 ENSG00000109321 ENSG00000101265 ENSG00000144560 ENSG00000139926 ENSG00000150457 ENSG00000151718 ENSG00000068028 ENSG00000186575 ENSG00000136997 ENSG00000107551 ENSG00000169435 PMC5241894__F7 Insulin-like growth factor receptor 1 (IGF-1R)– and mammalian target of rapamycin (mTOR)–induced alterations upon the canonical IGF-1R signaling cascade, mitogen-activated protein kinase (MAPK) and receptor tyrosine kinase RTKs in Ewing sarcoma (ES) ENSG00000115457 ENSG00000198793 ENSG00000169047 ENSG00000167658 ENSG00000164327 ENSG00000087842 PMC3488811__F1 Simplified diagram of choline-related one-carbon metabolism ENSG00000100714 ENSG00000173599 ENSG00000133027 PMC4431853__F7 House Dust Mite Allergen Regulates Constitutive Apoptosis of Normal and Asthmatic Neutrophils via Toll-Like Receptor 4 ENSG00000143546 ENSG00000163220 ENSG00000136869 PMC5597960__F7 Systemic lupus erythematosus (SLE)-activated platelets induce endothelial cell activation via an interleukin-1B (IL-1B) pathway ENSG00000125538 ENSG00000198670 PMC7230029__F1 Chromothripsis and telomere crisis: engines of genome instability ENSG00000183735 ENSG00000164430 PMC10242177__F1 Myostatin: a potential therapeutic target for metabolic syndrome PMC9704363__F6 Noncoding RNAs in cancer lipid metabolism ENSG00000131473 ENSG00000151726 ENSG00000113161 ENSG00000104549 ENSG00000169710 ENSG00000115419 PMC3574928__F1 De novo purine biosynthetic pathway in humans ENSG00000128050 PMC7937683__F8 Loss of desmoglein-2 promotes gallbladder carcinoma progression and resistance to EGFR-targeted therapy through Src kinase activation ENSG00000138798 ENSG00000146648 ENSG00000046604 PMC4287361__F1 Epstein-Barr virus Associated B-cell lymphomas: Pathogenesis and Clinical Outcomes ENSG00000102871 ENSG00000020633 ENSG00000123374 ENSG00000105810 PMC9576796__F5 Proposed metabolic pathway for anaerobic propane oxidation coupled to nitrate reduction ENSG00000114054 ENSG00000168040 PMC9704363__F5 Noncoding RNAs in cancer lipid metabolism ENSG00000151726 ENSG00000198793 ENSG00000169710 PMC3827622__F5 Proposed genetic networks of osseointegration ENSG00000125398 ENSG00000132326 ENSG00000168036 PMC4646252__F1 Interaction between SAMHD1 and deoxyguanosine kinase activities in the regulation of mitochondrial dGTP ENSG00000291814 PMC3338780__F8 Receptor Tyrosine Kinases Activate Canonical WNT/Beta-Catenin Signaling via MAP Kinase/LRP6 Pathway and Direct Beta-Catenin Phosphorylation ENSG00000281324 ENSG00000134982 ENSG00000168036 PMC8234227__F4 Natural Phytochemicals Derived from Gymnosperms in the Prevention and Treatment of Cancers ENSG00000177169 ENSG00000198793 ENSG00000100219 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC11941373__F7 Impact of DNA damage pathways on improving anticancer efficiency and reducing systemic drug resistance ENSG00000149311 ENSG00000012048 ENSG00000051180 PMC8163534__F8 Pharmacological Mechanisms Underlying the Therapeutic Effects of Danhong Injection on Cerebral Ischemia ENSG00000111837 PMC7981155__F2 WNT5a in Colorectal Cancer: Research Progress and Challenges ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC5393392__F3 Protein interactions during the flavivirus life cycle elucidated by MS-based proteomics ENSG00000065833 ENSG00000107862 ENSG00000151304 ENSG00000074319 ENSG00000110713 ENSG00000181467 ENSG00000099246 PMC6863093__F4 HVEM behaves as bidirectional switch based on environmental signals: ENSG00000226275 ENSG00000127191 PMC4569046__F5 Microbial subversion of neutrophil function leads to periodontal inflammation ENSG00000174125 ENSG00000198742 ENSG00000172005 ENSG00000172936 PMC6863093__F2 PD-1 exerts intrinsic suppression of T cell activity proximal to the TCR: ENSG00000291603 ENSG00000134982 PMC6379961__F1 Overview of PI3K/AKT/mTOR signaling pathway ENSG00000198793 PMC7582747__F3 Proposed regulation of PlGF and TGFB in early diabetic retinopathy ENSG00000261371 ENSG00000154188 ENSG00000127129 PMC8913403__F3 Therapeutic potential of mangiferin against kidney disorders and its mechanism of action: A review ENSG00000084774 PMC6425641__F1 Schematic presentation of strategy for SLA-PEB biosynthesis in E ENSG00000155926 ENSG00000102119 PMC4098112__F1 Regulation of muscle mass ENSG00000169047 PMC5110029__F1 Type I interferon signaling and type I interferonopathies as currently assigned ENSG00000213928 ENSG00000187608 ENSG00000104889 ENSG00000172922 ENSG00000102575 ENSG00000230034 ENSG00000142166 ENSG00000184979 ENSG00000101868 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 PMC6010520__F9 Proposed model for illustrating the essential roles of DNA sensors in recognition and innate interferons (IFNs) production during ectromelia virus (ECTV) infection ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000276561 PMC3051001__F1 RIP1 COMES BACK TO LIFE AS A CELL DEATH REGULATOR IN TNFR1 SIGALING ENSG00000127191 PMC9343696__F1 Crosstalk between the CBM complex/NFKB and MAPK/P27 signaling pathways of regulatory T cells contributes to the tumor microenvironment ENSG00000169291 ENSG00000181788 ENSG00000165891 ENSG00000135446 ENSG00000205250 ENSG00000105810 ENSG00000168610 PMC6889822__F4 Multiplexed Proteome Profiling of Carbon Source Perturbations in Two Yeast Species with SL-SP3-TMT ENSG00000100412 PMC7294914__F7 Proposed mechanism by which melatonin protects human renal proximal tubule epithelial cells against high glucose-induced fibrosis through the upregulation of PrPC ENSG00000140937 PMC10917537__F1 Fundamental ferroptosis-related intracellular pathways and mitochondrial regulation ENSG00000135423 ENSG00000078668 ENSG00000167468 ENSG00000167701 PMC3216277__F5 Pathways underlying the absorption of cholesterol from the intestinal lumen and its delivery to the liver ENSG00000138075 ENSG00000015520 ENSG00000120437 ENSG00000143921 PMC8124548__F3 Inhibitors of Chemoresistance Pathways in Combination with Ara-C to Overcome Multidrug Resistance in AML. A Mini Review ENSG00000002330 ENSG00000198793 PMC3216277__F1 Within the intestinal lumen, the micellar solubilization of sterols facilitates movement through the diffusion barrier overlying the surface of the absorptive cells ENSG00000138075 ENSG00000042832 ENSG00000138823 ENSG00000113161 ENSG00000120437 ENSG00000143921 PMC4632709__F3 Single network includes most splice regulatory genes dysregulated in MS ENSG00000291745 ENSG00000116044 ENSG00000108590 ENSG00000152601 ENSG00000130811 ENSG00000281022 ENSG00000141026 ENSG00000156603 ENSG00000139218 ENSG00000122566 ENSG00000065526 ENSG00000134057 ENSG00000005075 ENSG00000136997 ENSG00000284254 ENSG00000272398 ENSG00000136527 ENSG00000136146 ENSG00000275272 ENSG00000284944 ENSG00000176102 PMC3549263__F3 Low-dose radiation responsive genes linked to carcinogenesis ENSG00000132646 ENSG00000169047 ENSG00000185591 PMC2872667__F4 Skeletal Site-Related Variation in Human Trabecular Bone Transcriptome and Signaling ENSG00000105894 ENSG00000100234 ENSG00000087245 ENSG00000125398 ENSG00000142798 ENSG00000133110 ENSG00000113140 ENSG00000120885 ENSG00000170891 PMC8356007__F7 Exploring the Pharmacological Mechanism of Liuwei Dihuang Decoction for Diabetic Retinopathy: A Systematic Biological Strategy-Based Research ENSG00000157404 ENSG00000171105 ENSG00000007908 ENSG00000010671 PMC8313238__F5 CD38 in the age of COVID-19: a medical perspective ENSG00000162711 ENSG00000108691 ENSG00000125538 ENSG00000184012 ENSG00000172936 PMC2872667__F3 Skeletal Site-Related Variation in Human Trabecular Bone Transcriptome and Signaling ENSG00000105894 ENSG00000277753 ENSG00000066468 ENSG00000242252 ENSG00000170558 ENSG00000149294 ENSG00000077782 ENSG00000146648 ENSG00000155760 ENSG00000148848 ENSG00000121966 PMC7591852__F3 Dopamine-induced interactions of female mouse hypothalamic proteins with progestin receptor-A in the absence of hormone ENSG00000065833 ENSG00000100412 ENSG00000102109 ENSG00000146701 ENSG00000091140 ENSG00000126432 ENSG00000152556 PMC4811921__F3 Latency-associated nuclear antigen-mediated deregulation of cell cycle ENSG00000149311 ENSG00000175054 ENSG00000141867 ENSG00000135446 ENSG00000123374 ENSG00000101224 ENSG00000125968 PMC8568584__F7 Direct modulation of hepatocyte hepcidin signaling by iron ENSG00000170365 ENSG00000086991 ENSG00000168610 PMC10758887__F16 Current biomarkers and treatment strategies in Alzheimer disease: An overview and future perspectives ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11021710__F3 Cell cycle signaling pathway (A) and cellular senescence (B) ENSG00000118007 ENSG00000178999 ENSG00000167513 ENSG00000205250 ENSG00000073111 ENSG00000093009 ENSG00000137812 ENSG00000172167 ENSG00000105325 ENSG00000150907 ENSG00000113558 ENSG00000136997 ENSG00000105810 ENSG00000139687 ENSG00000166167 ENSG00000164109 ENSG00000116717 ENSG00000117399 ENSG00000141446 ENSG00000094804 ENSG00000198176 ENSG00000156970 ENSG00000132646 ENSG00000004897 ENSG00000105329 ENSG00000198793 ENSG00000164190 ENSG00000135476 ENSG00000277273 ENSG00000145386 ENSG00000166851 ENSG00000129933 ENSG00000134480 ENSG00000140534 ENSG00000175054 ENSG00000123374 ENSG00000071539 ENSG00000112742 ENSG00000253729 ENSG00000108055 ENSG00000175793 ENSG00000285109 ENSG00000101057 ENSG00000145604 ENSG00000149311 ENSG00000134057 ENSG00000164754 ENSG00000149554 ENSG00000080839 PMC1458968__F4 Structure, Expression, and Function of a Novel Intercalated Disc Protein, Xin ENSG00000170558 ENSG00000168036 ENSG00000167074 PMC4447079__F2 Illustration of protein modification by the ubiquitin proteasome system ENSG00000285246 ENSG00000116030 ENSG00000167508 PMC4710869__F1 Simplified schematic summarizing the BMP signalling pathway and genes that have to date been shown to be mutated in PAH and demonstrating that many of these mutations encode protein involved in BMP signalling ENSG00000163217 ENSG00000171303 PMC2666388__F1 DHA, NPD1, and BAPP-derived AB peptide signaling circuits in homeostatic aging and in AD ENSG00000137845 ENSG00000137642 PMC11580055__F7 Mechanism of EE improving secondary brain injury after TBI through the TLR2/NFKB/MMP9 pathway ENSG00000100985 PMC5412475__F1 Schematic presentation of the postsynaptic structure and function on the basis of acetylcholine receptor clustering centered on agrin- and Wnt-signalings, trans-synaptic communication and synaptic stabilization ENSG00000134569 ENSG00000030304 ENSG00000163914 ENSG00000087085 ENSG00000168036 ENSG00000112851 ENSG00000099942 PMC6502894__F1 Diagram showing the main paracrine and dichotomic autocrine functions of the IL-6/JAK/STAT3 pathway in the pathophysiology of skeletal muscle ENSG00000078098 ENSG00000168610 ENSG00000198947 PMC6939830__F1 S1P-S1P receptor signaling system ENSG00000205639 ENSG00000163914 ENSG00000183018 PMC7068780__F4 Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis ENSG00000136997 ENSG00000197272 PMC5601165__F2 Genetic progression in gastrointestinal stromal tumors: mechanisms and molecular interventions ENSG00000157404 ENSG00000172680 ENSG00000291971 ENSG00000198793 ENSG00000136997 ENSG00000134853 ENSG00000168610 PMC11604675__F1 Fusobacterium nucleatum facilitates the metastasis of CRC via modulating the expression of FadA-Wnt/catenin signaling cascade and NFKB/TLR4/MYD88 signaling pathway ENSG00000168036 ENSG00000172936 ENSG00000136869 ENSG00000115009 PMC8465622__F1 Repurposing Small Molecules to Target PPARG as New Therapies for Peripheral Nerve Injuries ENSG00000026508 ENSG00000168610 PMC7279384__F2 Mitochondrial Dynamics and Microglia as New Targets in Metabolism Regulation ENSG00000115138 ENSG00000121853 ENSG00000168610 PMC4964491__F3 Flii involvement in inflammation ENSG00000284571 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC7943556__F1 Signaling by the phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway ENSG00000146648 ENSG00000140443 PMC9604797__F2 Carotenoids from Marine Microalgae as Antimelanoma Agents ENSG00000135446 ENSG00000105810 ENSG00000139687 PMC9604797__F3 Carotenoids from Marine Microalgae as Antimelanoma Agents ENSG00000135446 ENSG00000168036 ENSG00000105810 PMC2631308__F1 Insulin resistance ENSG00000171105 ENSG00000042832 ENSG00000150907 ENSG00000169047 ENSG00000026103 PMC3252731__F1 TLR4 signaling pathway is highly regulated ENSG00000183735 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC4106326__F15 Model depicting how PPARB/D promotes H-RAS-induced cellular senescence, whereas ER stress attenuates H-RAS-induced cellular senescence ENSG00000140992 ENSG00000198793 PMC5294958__F1 TGFB/Smad4 signaling pathway ENSG00000137834 PMC7767754__F6 DDR pathway [, , ]: The DNA damage and response pathway: The figure depicts the causative agents and plausible DNA damage repair pathways ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000227345 ENSG00000138385 PMC7521960__F2 COVID-19 Patients Upregulate Toll-like Receptor 4-mediated Inflammatory Signaling That Mimics Bacterial Sepsis ENSG00000107562 ENSG00000291603 ENSG00000111321 ENSG00000150455 ENSG00000142224 ENSG00000095585 ENSG00000239732 ENSG00000077150 ENSG00000213658 ENSG00000135960 ENSG00000082512 ENSG00000125538 ENSG00000181374 ENSG00000136869 ENSG00000164342 ENSG00000100906 ENSG00000109320 ENSG00000269335 ENSG00000213341 ENSG00000116882 ENSG00000127191 ENSG00000073756 ENSG00000277943 ENSG00000149311 ENSG00000226275 ENSG00000170458 ENSG00000102245 ENSG00000186716 ENSG00000172936 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000162692 ENSG00000184216 PMC4316787__F4 Fourth-ranked enriched canonical pathway identified using IPA at 2 hpi – the CD40 signaling pathway ENSG00000162889 ENSG00000226275 ENSG00000082512 ENSG00000056558 ENSG00000104921 ENSG00000105639 ENSG00000175104 ENSG00000127191 ENSG00000168610 ENSG00000123268 PMC4316787__F3 Top-ranked enriched canonical pathway identified using IPA at 2 hpi – the IL-10 signaling pathway ENSG00000105397 ENSG00000185591 ENSG00000168610 PMC7543045__F9 Schematic model showing G10 activation of the NLRP3 inflammasome in porcine cells ENSG00000162711 ENSG00000150782 ENSG00000183735 ENSG00000125538 PMC6938671__F1 Two predominant DSB repair pathways in mammalian cells ENSG00000012048 ENSG00000284238 ENSG00000138346 ENSG00000178295 ENSG00000154920 ENSG00000188827 ENSG00000039650 ENSG00000165392 ENSG00000175643 ENSG00000197299 ENSG00000051180 ENSG00000139618 PMC11688383__F1 ER stress and activation of the UPR signaling pathways ENSG00000128272 ENSG00000100219 PMC8275894__F1 Function, Failure, and the Future Potential of Tregs in Type 1 Diabetes ENSG00000134460 ENSG00000160224 ENSG00000049768 PMC11688383__F2 Insults to airway epithelial cells, their impact on UPR and the consequences of UPR activation ENSG00000128272 ENSG00000100219 PMC11688383__F3 Inflammatory signaling pathway regulated by UPR ENSG00000128272 ENSG00000169136 ENSG00000265972 ENSG00000127191 PMC7573563__F1 Innate immune response during ADE and non-ADE dengue infection ENSG00000107201 ENSG00000164342 PMC11688383__F5 ER stress-mediated autophagy and the possible mechanisms ENSG00000177169 ENSG00000123395 ENSG00000198382 ENSG00000128272 ENSG00000127191 ENSG00000145782 ENSG00000057663 PMC4980033__F3 Modelling the Structure and Dynamics of Biological Pathways ENSG00000047410 ENSG00000126883 ENSG00000058804 ENSG00000196313 PMC8192490__F3 miR-940 is a new biomarker with tumor diagnostic and prognostic value ENSG00000137673 ENSG00000135446 ENSG00000168036 ENSG00000168610 PMC2642890__F2 Posttranscriptional regulation of gene networks by GREs ENSG00000002330 ENSG00000159388 ENSG00000122877 ENSG00000277273 ENSG00000196470 ENSG00000166851 ENSG00000134480 ENSG00000106546 ENSG00000115317 ENSG00000157557 ENSG00000175054 ENSG00000159216 ENSG00000153767 ENSG00000136997 ENSG00000150907 ENSG00000137265 ENSG00000118515 ENSG00000056558 ENSG00000123374 ENSG00000100219 ENSG00000120868 ENSG00000169375 ENSG00000026103 ENSG00000116717 ENSG00000067900 ENSG00000149311 ENSG00000153487 ENSG00000177606 ENSG00000066136 ENSG00000084774 PMC11814165__F2 Illustrating of the binding mechanisms of berberine with PLA2, MD2, BACE1, AB1-42, TGFBR1, and JAK2 in human cells ENSG00000142192 ENSG00000172936 ENSG00000136869 PMC6558179__F5 Underlying mechanism of SSa on T cell-mediated immune surveillance in breast cancer ENSG00000138378 ENSG00000105397 PMC5702962__F1 Structure of (A) HGF and (B) Met ENSG00000019991 ENSG00000070831 ENSG00000198793 ENSG00000168610 PMC8616147__F6 RASSF1A-Mediated Suppression of Estrogen Receptor Alpha (ERA)-Driven Breast Cancer Cell Growth Depends on the Hippo-Kinases LATS1 and 2 PMC10937431__F4 Signalling pathways and targets of botanical medicine flavonoids against CIRI-induced PANoptosis and ferroptosis ENSG00000278718 ENSG00000124256 ENSG00000137275 ENSG00000102871 ENSG00000091106 ENSG00000168040 ENSG00000127191 ENSG00000079999 ENSG00000167468 ENSG00000082512 ENSG00000111684 ENSG00000157625 ENSG00000168404 ENSG00000064012 ENSG00000285379 PMC5303000__F2 Role of the N-MYC downstream-regulated gene family in reprogramming cancer metabolism under hypoxia ENSG00000134086 ENSG00000101079 ENSG00000136997 ENSG00000168036 ENSG00000103034 ENSG00000165795 ENSG00000115419 ENSG00000159399 PMC4323240__F7 Macrophage Activities in Proliferation, Lysosome, and Phagosome by the Nonspecific Immunostimulator, Mica ENSG00000144063 ENSG00000124102 ENSG00000132646 ENSG00000123374 ENSG00000276876 PMC6803663__F1 Flow diagram illustrating the molecular methodology and frequency results of CRC cases diagnosed between 2011–2012 ENSG00000095002 ENSG00000122512 PMC3991965__F2 Prostaglandin Analogues on Aqueous Humor Outflow Pathways ENSG00000163914 ENSG00000168036 ENSG00000146648 PMC9460961__F2 Combination strategies to optimize the efficacy of chimeric antigen receptor T cell therapy in haematological malignancies ENSG00000181847 ENSG00000186716 ENSG00000198793 ENSG00000113263 ENSG00000010671 PMC7339783__F9 Graphic summary of the findings of the present study ENSG00000125538 ENSG00000189403 ENSG00000136869 PMC10937431__F3 Signalling pathways and targets of botanical medicine flavonoids against CIRI-induced autophagy ENSG00000177169 ENSG00000110497 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC8508861__F3 Photodynamic Therapy Induced Cell Death Mechanisms in Breast Cancer ENSG00000102871 ENSG00000168040 PMC4433804__F1 Catalytic mechanism of a retinoid isomerase essential for vertebrate vision ENSG00000135437 ENSG00000121207 ENSG00000116745 PMC9277309__F5 Molecular Mechanisms of Epigenetic Regulation, Inflammation, and Cell Death in ADPKD ENSG00000008710 ENSG00000198793 ENSG00000096717 ENSG00000143499 PMC7728437__F1 On-Off DSGCs in Gabra2 cKO mice show reduced direction selectivity and reduced null-direction inhibition in the noisy background ENSG00000151834 ENSG00000095787 PMC9277309__F3 Molecular Mechanisms of Epigenetic Regulation, Inflammation, and Cell Death in ADPKD ENSG00000171791 ENSG00000026103 PMC6927547__F1 Key anti-obesity strategies and pharmacological agents ENSG00000168214 ENSG00000142611 ENSG00000168610 PMC3879631__F6 Model for potential roles of SIRT7 in ribosome biogenesis ENSG00000187531 ENSG00000198793 PMC5008583__F3 KEGG in Graphviz view of T-cell receptor signaling pathways on a canonical signaling pathway with gene methylation chip data ENSG00000104365 ENSG00000151490 ENSG00000291603 ENSG00000042832 ENSG00000100906 ENSG00000109320 ENSG00000198851 ENSG00000163599 ENSG00000269335 ENSG00000115904 ENSG00000213341 ENSG00000043462 ENSG00000169032 ENSG00000006062 ENSG00000121879 ENSG00000141968 ENSG00000188389 ENSG00000213658 ENSG00000149269 ENSG00000102245 ENSG00000010810 ENSG00000113263 ENSG00000124181 PMC4440424__F2 Class I PI3K pathway ENSG00000140992 ENSG00000002330 ENSG00000150907 ENSG00000198793 ENSG00000164327 PMC5008583__F4 KEGG in Graphviz view of Jak–STAT signaling pathways on a canonical signaling pathway with gene methylation chip data ENSG00000112576 ENSG00000213928 ENSG00000005339 ENSG00000114737 ENSG00000115904 ENSG00000137193 ENSG00000105639 ENSG00000121879 ENSG00000196396 ENSG00000166068 ENSG00000164056 ENSG00000122756 ENSG00000136997 ENSG00000115145 PMC4214394__F1 Activation of mammalian target of rapamycin occurs through a complex signaling cascade ENSG00000198793 ENSG00000284161 ENSG00000167658 ENSG00000164327 PMC8797727__F3 p16 a biomarker of aging and tolerance for cancer therapy ENSG00000135446 ENSG00000105810 PMC5343994__F1 Mutation in the von Hippel–Lindau gene (VHL) induces loss (red ×: HIF-2a is no longer inhibited) of the regulatory tumour suppressor p-VHL and catalyses the “von Hippel–Lindau-hypoxia-inducible factor” VHL-HIF pathway ENSG00000047410 ENSG00000134086 ENSG00000163235 PMC7074405__F1 Curcumin exerts various effects on the malignant activities of tumor cells ENSG00000019991 ENSG00000168610 PMC8709963__F9 Dietary supplementation of inulin alleviates metabolism disorders in gestational diabetes mellitus mice via RENT/AKT/IRS/GLUT4 pathway ENSG00000042832 ENSG00000005882 ENSG00000104918 ENSG00000115461 ENSG00000067177 ENSG00000013375 PMC5192396__F2 Inhibition of ribonuclease L (RNase L) activation by picornavirus proteins ENSG00000088888 ENSG00000138757 ENSG00000135828 ENSG00000276561 PMC5876656__F1 The Hippo signaling pathway is composed of neurofibromin 2 (NF2), mammalian STE20-like protein kinase 1/2 (Mst1/2) and large tumor suppressor 1/2 (Lats1/2) ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC3285398__F1 Toll-like Receptors (TLRs) recognize specialized structural motifs on the microbes known as pathogen-associated molecular patterns (PAMPs) ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC3285398__F2 Proposed mechanisms of interaction between TLRs and MUCs: I ENSG00000168036 ENSG00000175104 PMC4625546__F1 Is Retinol Binding Protein 4 a Link Between Adiposity and Cancer? ENSG00000121207 ENSG00000168610 PMC7099488__F1 Bile acid synthesis in the liver ENSG00000138135 ENSG00000276559 ENSG00000167910 ENSG00000036530 ENSG00000180432 ENSG00000115271 ENSG00000135929 PMC7296156__F3 Biological properties of cmvIL10 in myeloid progenitors (during lytic infection) ENSG00000170458 ENSG00000276051 ENSG00000168610 ENSG00000121966 PMC2650409__F6 c-Src Regulates Akt Signaling in Response to Ghrelin via Beta-Arrestin Signaling-Independent and -Dependent Mechanisms ENSG00000084093 ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC5879999__F1 Metabolic interventions suggested by OptForce for increasing production of octanoic acid (C8) in E ENSG00000122966 ENSG00000074696 ENSG00000172005 ENSG00000168040 PMC7016617__F2 Signaling pathways modulated by SCD1 activity and levels ENSG00000128272 ENSG00000002330 ENSG00000134982 ENSG00000086991 ENSG00000168036 PMC9179486__F1 Kynurenine Pathway and Cancer: Why Keep It Simple When You Can Make It Complicated ENSG00000183077 PMC4048950__F10 Redox control of p53 in the transcriptional regulation of TGFB1 target genes through SMAD cooperativity ENSG00000149311 ENSG00000175054 ENSG00000105698 ENSG00000146648 PMC9179486__F3 Kynurenine Pathway and Cancer: Why Keep It Simple When You Can Make It Complicated ENSG00000183077 ENSG00000125968 PMC2724105__F2 The postreceptor insulin signaling pathway and insulin-independent 5′-adenosine monophosphate kinase (AMPK) beginning from insulin binding to its receptor to GLUT4 translocation via vesicular trafficking ENSG00000005882 PMC7407683__F5 FSH and ovarian cancer ENSG00000138741 PMC9495820__F8 Formyl-Peptide Receptor 2 Signaling Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming of Lung Cancer Cells ENSG00000171049 ENSG00000115419 ENSG00000084774 PMC10887103__F5 Defective PI3K/Akt pathway in T2DM results in insulin resistance and the activation of the pro-inflammatory, pro-apoptotic inhibition of eNOS and glycogen production ENSG00000198793 ENSG00000198626 PMC7407683__F1 FSHR is expressed in multiple organs related to metabolic diseases and FSH/FSHR participates in the regulation of cellular activities and metabolic processes ENSG00000121039 ENSG00000130164 ENSG00000198793 ENSG00000062282 ENSG00000026103 PMC7407683__F2 FSH and obesity ENSG00000121039 ENSG00000062282 ENSG00000026103 PMC3427269__F1 AGER/RAGE-mediated autophagy promotes pancreatic tumorigenesis and bioenergetics through the IL6-pSTAT3 pathway ENSG00000291971 ENSG00000168610 PMC6515458__F3 Protein–protein interaction (PPI) network in muscle wasting in cancer cachexia ENSG00000133020 ENSG00000107562 ENSG00000134363 ENSG00000167552 ENSG00000168610 ENSG00000081189 ENSG00000185774 ENSG00000182326 ENSG00000090273 ENSG00000149968 ENSG00000158022 ENSG00000149269 ENSG00000150907 ENSG00000127824 ENSG00000177666 ENSG00000171819 ENSG00000124253 ENSG00000139112 PMC6515458__F1 MicroRNA-regulated networks in muscle wasting during cancer cachexia based on meta-analysis data ENSG00000107562 ENSG00000158022 ENSG00000150907 ENSG00000168610 ENSG00000081189 ENSG00000139112 PMC2694962__F1 Schematic illustration of overview of one-carbon metabolism pathway, linking to methylation reactions and nucleotide synthesis ENSG00000124275 ENSG00000035928 ENSG00000116984 PMC9333902__F1 Immunological mechanism underlying severe fever with thrombocytopenia syndrome (Review) ENSG00000121060 ENSG00000164342 PMC8799426__F3 Trend of CRISPR-Based Technologies in COVID-19 Disease: Beyond Genome Editing ENSG00000130234 PMC9343696__F2 Crosstalk between the CBM complex/NFKB and MAPK/P27 signaling pathways of regulatory T cells contributes to the tumor microenvironment ENSG00000175104 PMC11876862__F1 Mechanisms of protein degradation and synthesis in muscles ENSG00000170365 ENSG00000198793 ENSG00000158828 ENSG00000135414 ENSG00000145782 ENSG00000168610 PMC7540572__F1 Tricin biosynthetic pathway from the key pathway‐branching intermediate, p‐coumaroyl‐CoA, with generic enzymes in grasses noted in green (Lam et al., ; Eloy et al., ), and in red are those from Medicago sativa (Ms) and M ENSG00000117525 ENSG00000084774 PMC7846970__F3 ACE2/Ang-(1-7)/Mas1 axis and the vascular system: vasoprotection to COVID-19-associated vascular disease PMC3141233__F7 A model for the role of FANCD2 in Ad replication-dependent recombination ENSG00000175054 ENSG00000144554 ENSG00000197299 PMC3322146__F8 Role of miR-148a in Hepatitis B Associated Hepatocellular Carcinoma ENSG00000168036 PMC4996367__F1 Immune cell-derived complement on T cell immune responses ENSG00000162711 ENSG00000134982 ENSG00000117335 PMC4730276__F2 EGFR function in hepatocytes and Kupffer cells during hepatocellular carcinoma (HCC) formation ENSG00000172936 ENSG00000146648 PMC9453478__F1 Fanconi anemia and dyskeratosis congenita/telomere biology disorders: Two inherited bone marrow failure syndromes with genomic instability ENSG00000131944 ENSG00000083093 ENSG00000144554 ENSG00000188827 ENSG00000187790 ENSG00000108384 ENSG00000132383 PMC8888452__F1 Targeting Epithelial-to-Mesenchymal Transition in Radioresistance: Crosslinked Mechanisms and Strategies ENSG00000168214 ENSG00000283780 ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC6381758__F7 Modified KEGG map of the JNK and p38 MAP kinase signaling pathway showing transcriptional changes ENSG00000162889 ENSG00000105329 ENSG00000108861 ENSG00000102871 ENSG00000120875 ENSG00000095015 ENSG00000065559 ENSG00000197442 ENSG00000101224 ENSG00000162302 ENSG00000127191 ENSG00000173327 ENSG00000081189 ENSG00000114738 ENSG00000104814 ENSG00000011566 ENSG00000138166 ENSG00000126803 ENSG00000177606 ENSG00000100784 ENSG00000131196 ENSG00000026103 PMC9023592__F1 Product of AS of pre-mRNA: lncRNA ENSG00000111537 ENSG00000185745 ENSG00000185885 PMC8377458__F2 Narrative Review of the Renin-Angiotensin-Aldosterone System in the Placenta and Placental Bed of HIV Infected Women of African Ancestry with Preeclampsia ENSG00000184156 PMC8639599__F1 Bone Marrow Microenvironment Mechanisms in Acute Myeloid Leukemia ENSG00000178860 ENSG00000090534 ENSG00000148400 ENSG00000117400 ENSG00000170558 PMC7432306__F4 Reconstructed metabolic map of xanthan biosynthesis in Xpm ENSG00000197713 ENSG00000084072 ENSG00000168938 PMC8639599__F2 Bone Marrow Microenvironment Mechanisms in Acute Myeloid Leukemia ENSG00000178860 ENSG00000107562 ENSG00000026508 ENSG00000174059 ENSG00000121966 PMC3956502__F4 Mechanisms underlying the inhibition of interferon signaling by viruses ENSG00000105397 PMC4504428__F2 MDM2-p53 Pathway in Hepatocellular Carcinoma ENSG00000153487 ENSG00000142082 PMC2905205__F1 Signalling routes of copper and hydrogen peroxide ENSG00000138443 PMC9558762__F3 Physiological and pathological roles of Hic-5 in several organs (Review) ENSG00000168036 ENSG00000136869 ENSG00000168040 ENSG00000196628 PMC8291223__F8 A High-Grain Diet With a Buffering Agent on Milk Protein Synthesis in Lactating Goats ENSG00000198793 ENSG00000284161 ENSG00000167658 ENSG00000086730 PMC9389465__F2 Glucose transporters: Important regulators of endometrial cancer therapy sensitivity ENSG00000011198 ENSG00000138798 ENSG00000198793 ENSG00000170801 PMC4050178__F1 Brief Overview of DNA Damage Repair: Three common types of DNA damage are depicted in this image as well as an summary of the pathways/proteins that are activated in response to each type of damage ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000138385 PMC5204344__F4 let-7c and miR-10b target multiple genes in regulatory networks ENSG00000137834 ENSG00000008710 ENSG00000184254 ENSG00000157404 ENSG00000071655 ENSG00000291348 ENSG00000175029 ENSG00000120539 ENSG00000112312 ENSG00000038382 ENSG00000138207 ENSG00000115884 ENSG00000171456 ENSG00000143320 ENSG00000133740 ENSG00000100784 ENSG00000291501 ENSG00000105204 ENSG00000111642 PMC8804744__F3 Mitochondria in Physiology of Chondrocytes and Diseases of Osteoarthritis and Rheumatoid Arthritis ENSG00000138798 ENSG00000125538 PMC11863469__F10 PI3K/AKT/mTOR pathway in GBM progression ENSG00000002330 ENSG00000155792 ENSG00000167965 PMC7656585__F2 CP-25 on cells and possible mechanisms ENSG00000177455 ENSG00000139193 ENSG00000107562 ENSG00000125538 ENSG00000118520 ENSG00000112149 ENSG00000127191 ENSG00000121966 ENSG00000102977 PMC11863469__F11 TGFB signaling in GBM progression PMC4397972__F4 Gene network analysis for 18 key genes involved in age-dependent tumor progression ENSG00000284832 ENSG00000115884 ENSG00000105329 ENSG00000134057 ENSG00000213614 ENSG00000196154 ENSG00000168036 ENSG00000168040 ENSG00000111348 ENSG00000164305 ENSG00000151348 ENSG00000107581 PMC11863469__F12 Notch signaling in GBM progression ENSG00000135547 ENSG00000114315 PMC6894939__F2 Gluconeogenesis in cancer cells – repurposing of a starvation-induced metabolic pathway? ENSG00000130957 ENSG00000122966 ENSG00000173599 ENSG00000172005 ENSG00000124253 PMC8290014__F6 TLR4 in parthanatos and the MyD88 and/or the PI3K signaling pathway in parthanatos ENSG00000172936 ENSG00000136869 ENSG00000146648 PMC9366916__F3 Breaking the aging epigenetic barrier ENSG00000149311 ENSG00000175054 PMC6894939__F5 Gluconeogenesis in cancer cells – repurposing of a starvation-induced metabolic pathway? ENSG00000173599 ENSG00000124253 PMC6148080__F19 SST5signaling leading to inhibition of hormone secretion and proliferation ENSG00000069482 ENSG00000198793 ENSG00000145321 ENSG00000157005 PMC9177323__F6 Single-Cell Analysis Reveals the Role of the Neuropeptide Receptor FPR2 in Monocytes in Kawasaki Disease: A Bioinformatic Study ENSG00000116161 ENSG00000143549 ENSG00000072274 ENSG00000138071 ENSG00000136167 PMC11764157__F6 CBG on AD models ENSG00000105397 ENSG00000137033 ENSG00000125538 ENSG00000145777 PMC3469658__F5 Molecular Phenotyping of Immune Cells from Young NOD Mice Reveals Abnormal Metabolic Pathways in the Early Induction Phase of Autoimmune Diabetes ENSG00000142192 ENSG00000125538 ENSG00000136997 ENSG00000167552 ENSG00000136167 PMC8705098__F2 Complement System in Alzheimer’s Disease ENSG00000236625 PMC3469658__F6 Molecular Phenotyping of Immune Cells from Young NOD Mice Reveals Abnormal Metabolic Pathways in the Early Induction Phase of Autoimmune Diabetes ENSG00000044115 ENSG00000132478 ENSG00000011485 ENSG00000111348 ENSG00000196684 ENSG00000164305 ENSG00000163515 ENSG00000276068 PMC3469658__F3 Molecular Phenotyping of Immune Cells from Young NOD Mice Reveals Abnormal Metabolic Pathways in the Early Induction Phase of Autoimmune Diabetes ENSG00000100410 ENSG00000198918 ENSG00000117519 ENSG00000079257 ENSG00000133401 ENSG00000145592 ENSG00000134900 ENSG00000146223 ENSG00000161016 ENSG00000092621 ENSG00000141480 ENSG00000122223 ENSG00000129515 ENSG00000136997 ENSG00000164136 ENSG00000119929 ENSG00000112306 PMC3469658__F4 Molecular Phenotyping of Immune Cells from Young NOD Mice Reveals Abnormal Metabolic Pathways in the Early Induction Phase of Autoimmune Diabetes ENSG00000116001 ENSG00000112195 ENSG00000092621 ENSG00000205302 ENSG00000169499 ENSG00000129515 ENSG00000188404 ENSG00000164136 ENSG00000113851 ENSG00000146648 ENSG00000007171 PMC4100211__F1 Proposed frame work for mRNA nanoparticle mediated tumour vaccination ENSG00000139193 ENSG00000172936 ENSG00000164342 PMC6370632__F1 Signal transduction pathway related to the immune-regulation of botanical polysaccharides in macrophage activation ENSG00000170458 ENSG00000177606 ENSG00000172936 ENSG00000175104 PMC3144530__F1 Schematic overview of proposed G protein-coupled oestrogen receptor 1 (GPER1) signalling ENSG00000291971 ENSG00000113070 ENSG00000146648 PMC6620384__F1 Regulatory mechanisms of Robo4 and their effects on angiogenesis ENSG00000145147 ENSG00000154133 ENSG00000291971 ENSG00000165527 ENSG00000112715 PMC4280516__F2 Cellular entry of HCV particles ENSG00000130164 ENSG00000110651 ENSG00000146648 PMC3969788__F4 Strategies for Delivery of Therapeutics into the Central Nervous System for Treatment of Lysosomal Storage Disorders ENSG00000102189 ENSG00000291971 ENSG00000163914 PMC3959213__F10 Reduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway ENSG00000180210 ENSG00000126457 PMC7957493__F4 Mutations in components of niche-signalling pathways lead to “ISC emancipation” and subversion of homeostatic mechanisms ENSG00000019991 ENSG00000134982 ENSG00000148400 ENSG00000138798 ENSG00000106483 ENSG00000104332 ENSG00000177663 ENSG00000183734 ENSG00000120057 ENSG00000163914 ENSG00000136997 ENSG00000019549 ENSG00000026508 ENSG00000108375 ENSG00000114315 ENSG00000112115 ENSG00000168646 ENSG00000109670 PMC11863469__F17 SHH signaling pathway in GBM, particularly in GSCs: In the absence of the hedgehog (HH) ligand, the Ptch receptor inhibits Smo, leading to the formation of GliR, a repressor that suppresses the expression of target genes ENSG00000164690 ENSG00000128602 PMC6024750__F3 Outline of the three main pathways of colon carcinogenesis ENSG00000157764 ENSG00000134982 ENSG00000170430 ENSG00000095002 ENSG00000064933 PMC3631444__F6 The ERK1/2 pathway regulates testosterone synthesis by coordinately regulating the expression of steroidogenic genes in Leydig cells ENSG00000073737 PMC6594622__F5 Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures ENSG00000023445 ENSG00000169248 ENSG00000115008 ENSG00000118503 ENSG00000138755 ENSG00000108700 ENSG00000056558 ENSG00000074966 ENSG00000113263 ENSG00000102010 ENSG00000135605 ENSG00000010671 PMC11863469__F16 Complex and dynamic interactions between signaling pathways in shaping GBM progression, therapeutic resistance, and disease outcomes (*To draw this figure, data from the reports in references [39, 146, 155, 245, 249, 294, 333–380] were used ENSG00000157764 ENSG00000070831 ENSG00000026508 ENSG00000146648 PMC6148080__F20 Differential trafficking of somatostatin receptors ENSG00000157005 ENSG00000138398 PMC8649443__F6 Metabolic endophenotype associated with right ventricular glucose uptake in pulmonary hypertension ENSG00000059573 ENSG00000118520 ENSG00000115419 PMC4357780__F3 iBIG: An Integrative Network Tool for Supporting Human Disease Mechanism Studies ENSG00000105664 ENSG00000111537 ENSG00000198517 PMC6176117__F3 Schematic outline of the intracellular signalization in the retinohypothalamic tract ENSG00000179094 ENSG00000096717 PMC5610669__F3 Examples of IGF-targeted agents ENSG00000140443 PMC5610669__F4 Crosstalk between IGF-1R and other RTKs/steroid hormone receptors ENSG00000171105 ENSG00000169047 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC5564764__F7 BMX/Etk promotes cell proliferation and tumorigenicity of cervical cancer cells through PI3K/AKT/mTOR and STAT3 pathways ENSG00000198793 ENSG00000102010 ENSG00000168610 PMC8972406__F1 Solar-Driven Producing of Value-Added Chemicals with Organic Semiconductor-Bacteria Biohybrid System ENSG00000188158 ENSG00000150787 PMC4103166__F3 Circadian Clock in Cancer Development and Therapy ENSG00000149311 ENSG00000168036 PMC3691869__F6 Schematic outline of the regulation of EGFR internalization and mediated signaling by the CIN85–SH3GL2–Cbl complex ENSG00000107295 ENSG00000138798 ENSG00000168036 ENSG00000168610 ENSG00000146648 PMC6601370__F10 KEGG pathways enriched by the differentially expressed mRNAs in the competing endogenous RNA network ENSG00000213658 ENSG00000163914 ENSG00000084774 PMC10536053__F3 Targeting DNA Damage Repair and Immune Checkpoint Proteins for Optimizing the Treatment of Endometrial Cancer ENSG00000012061 ENSG00000138346 ENSG00000197299 ENSG00000177084 ENSG00000310560 PMC10536053__F4 Targeting DNA Damage Repair and Immune Checkpoint Proteins for Optimizing the Treatment of Endometrial Cancer ENSG00000149311 ENSG00000175054 ENSG00000169245 ENSG00000183735 ENSG00000164430 ENSG00000164136 ENSG00000123374 ENSG00000138385 PMC4401125__F1A HSPs regulatory function in the intrinsic (A), extrinsic and caspase independent pathways to death (B) ENSG00000102145 ENSG00000002330 ENSG00000084774 PMC8666431__F7 Precise Identification of Recurrent Somatic Mutations in Oral Cancer Through Whole-Exome Sequencing Using Multiple Mutation Calling Pipelines ENSG00000066468 ENSG00000197081 ENSG00000149782 ENSG00000123104 ENSG00000047936 ENSG00000182621 ENSG00000121879 ENSG00000077782 ENSG00000146648 PMC4201519__F2 Integrated microRNA and mRNA Transcriptome Sequencing Reveals the Potential Roles of miRNAs in Stage I Endometrioid Endometrial Carcinoma ENSG00000145604 ENSG00000121552 ENSG00000094804 ENSG00000135446 ENSG00000132646 ENSG00000123374 ENSG00000164754 ENSG00000205250 ENSG00000105810 ENSG00000277273 ENSG00000117399 ENSG00000276876 PMC3287586__F2 Preimplantation development pathway ENSG00000165556 ENSG00000111057 ENSG00000254986 ENSG00000187140 ENSG00000168036 ENSG00000137270 ENSG00000136826 ENSG00000065717 ENSG00000242221 ENSG00000170365 ENSG00000148498 ENSG00000134755 ENSG00000147869 ENSG00000136997 ENSG00000128342 ENSG00000179348 ENSG00000154096 ENSG00000113196 ENSG00000285109 ENSG00000164587 ENSG00000197905 ENSG00000150459 ENSG00000081051 ENSG00000168610 ENSG00000071564 ENSG00000188910 ENSG00000124216 ENSG00000164736 ENSG00000143768 ENSG00000243709 ENSG00000119715 PMC10857159__F6 Expression of DEGs involved in the plant hormone signal transduction pathway of M ENSG00000110934 PMC10744863__F1 Pathophysiology of acquired aplastic anemia (AA) ENSG00000111537 ENSG00000049768 ENSG00000168610 ENSG00000026103 PMC10031108__F9 Myricetin attenuates hypoxic-ischemic brain damage in neonatal rats via NRF2 signaling pathway ENSG00000120868 ENSG00000079999 PMC5610669__F1 Components of the insulin/IGF axis ENSG00000197081 ENSG00000140443 PMC5610669__F2 IGF-1R downstream signaling ENSG00000171105 ENSG00000002330 ENSG00000169047 ENSG00000140443 PMC8258330__F2 Recent Advances in Understanding Peripheral Taste Decoding I: 2010 to 2020 ENSG00000185933 ENSG00000163982 ENSG00000183128 ENSG00000070985 ENSG00000110218 ENSG00000137841 ENSG00000288455 ENSG00000075213 PMC4934657__F3 Fanconi Anemia Proteins, DNA Interstrand Crosslink Repair Pathways, and Cancer Therapy ENSG00000175054 ENSG00000083093 ENSG00000077152 ENSG00000162607 PMC8687625__F9 Detecting Critical Functional Ingredients Group and Mechanism of Xuebijing Injection in Treating Sepsis ENSG00000149311 ENSG00000002330 ENSG00000101871 ENSG00000170458 ENSG00000196839 ENSG00000186716 ENSG00000136869 ENSG00000162692 ENSG00000111816 ENSG00000135517 PMC8824883__F2 Cell division control protein 42 in tumor and non-tumor diseases: A systematic review ENSG00000070831 ENSG00000168036 ENSG00000146648 PMC9359465__F2 Cerebral malaria induced by plasmodium falciparum: clinical features, pathogenesis, diagnosis, and treatment ENSG00000163914 ENSG00000162692 PMC5749629__F2 Hepatic methionine metabolism is closely linked to GSH synthesis PMC8625415__F8 Prognostic Biomarkers of NIMA (Never in Mitosis, Gene A)-Related Kinase (NEK) Family Members in Breast Cancer ENSG00000125817 ENSG00000117697 ENSG00000134982 ENSG00000188404 ENSG00000117399 ENSG00000149503 PMC6150985__F2 P53 is the most important regulator in DNA damage ENSG00000149311 ENSG00000175054 PMC6514907__F1 Enhancement of SUMOylation in glioblastoma contributes to alterations in multiple cellular processes leading to an increased malignant phenotype ENSG00000079387 ENSG00000142230 ENSG00000033800 ENSG00000105810 ENSG00000116030 PMC4732808__F9 Blockade of KCNN4 by Clt accelerates wound healing at least in part by transactivation of the PI3K pathway ENSG00000122966 ENSG00000104783 ENSG00000138798 ENSG00000146648 PMC4059167__F1 Canonical catecholaminergic neuron is one that generates dopamine, noradrenaline or adrenaline ENSG00000123454 ENSG00000141744 PMC4144112__F1 Genistein modulates a critical TGFB signaling pathway in human prostate cancer ENSG00000162889 ENSG00000170365 PMC4876503__F6 Hepatitis B virus inhibits intrinsic RIG-I and RIG-G immune signaling via inducing miR146a ENSG00000088888 ENSG00000115415 ENSG00000142166 PMC9459389__F3 Mechanisms of ferroptosis and its role in alzheimer’s disease ENSG00000140564 ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000115419 PMC8191844__F1 Immunometabolism: Towards a Better Understanding the Mechanism of Parasitic Infection and Immunity ENSG00000118520 PMC6357148__F2 Filovirus replication cycle showing host and viral proteins that either promote (green boxes) or block (red boxes) virion assembly and release ENSG00000069869 ENSG00000187608 ENSG00000078747 ENSG00000074319 ENSG00000151929 ENSG00000123124 PMC7519203__F2 Proposed mechanisms and time course of SARS-CoV-2 infection when using a ketone-based metabolic therapy ENSG00000130234 ENSG00000150907 PMC4372177__F5 Top Kegg pathways enriched with aDMCs identified by the FatiGO analysis ENSG00000170608 ENSG00000111537 ENSG00000135100 ENSG00000114315 ENSG00000084774 PMC5916961__F1 Mitochondria are a platform for pattern recognition receptors (PRRs) signal transduction and regulation ENSG00000174125 ENSG00000162711 ENSG00000088888 ENSG00000125538 ENSG00000136869 ENSG00000130159 ENSG00000175104 ENSG00000276561 PMC7519203__F8 Proinflammatory signaling that occurs during viral infection and mechanisms through which R-BHB inhibits this signaling ENSG00000162711 ENSG00000088888 ENSG00000147162 ENSG00000167207 ENSG00000172936 ENSG00000265972 ENSG00000168040 ENSG00000175104 ENSG00000159335 ENSG00000168610 ENSG00000184216 PMC4261510__F1 Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167074 PMC3650620__F4 Cross-talk between insulin and inflammatory signaling pathways ENSG00000162711 ENSG00000102871 ENSG00000169047 ENSG00000198793 ENSG00000136869 ENSG00000127191 ENSG00000168610 PMC4261510__F2 Hippo signaling pathway ENSG00000186575 PMC8504269__F2 Mechanosensitive Non-Coding RNAs in Osteogenesis of Mesenchymal Stem Cells PMC10938139__F2 Research progress of periostin and osteoporosis ENSG00000138795 ENSG00000134982 ENSG00000168036 PMC10938139__F1 Research progress of periostin and osteoporosis ENSG00000178860 ENSG00000182533 ENSG00000281324 ENSG00000162337 ENSG00000168487 PMC7349630__F2 Signaling pathways and mechanistic drivers of epithelial-mesenchymal transition (EMT) and endothelial-mesenchymal transition (EndMT) in age-related macular degeneration (AMD) ENSG00000110799 ENSG00000198793 ENSG00000168036 PMC10669822__F6 “PPAR signaling pathway” was an upregulated KEGG pathway for the transcriptomics profiling of HMEC-1 treated with MPE (0 ENSG00000150991 ENSG00000100979 ENSG00000165269 ENSG00000173391 ENSG00000140465 PMC8678153__F4 Synthetic lethality of ATM and ATR ENSG00000149311 ENSG00000175054 PMC3660856__F3 Molecular Basis of DNA Recognition in the Immune System ENSG00000162711 ENSG00000163568 ENSG00000125538 PMC6873089__F2 Mutational landscape of HCC ENSG00000149311 ENSG00000124102 ENSG00000177189 ENSG00000116044 ENSG00000134982 ENSG00000198793 ENSG00000164362 ENSG00000112715 ENSG00000139687 ENSG00000189079 ENSG00000079999 ENSG00000163631 PMC9599207__F1 Targeting the Hippo Pathway in Gastric Cancer and Other Malignancies in the Digestive System: From Bench to Bedside ENSG00000150457 ENSG00000131023 PMC12130507__F5 KEGG pathways “VEGF signaling pathway”, significantly associated with CD36 abundance ENSG00000002330 ENSG00000070831 PMC9599207__F2 Targeting the Hippo Pathway in Gastric Cancer and Other Malignancies in the Digestive System: From Bench to Bedside ENSG00000150457 PMC12130507__F6 KEGG pathways “Glutamatergic Synapse”, significantly associated with CD36 abundance PMC8509025__F1 Molecular Functions and Pathways of Plastidial Starch Phosphorylase (PHO1) in Starch Metabolism: Current and Future Perspectives ENSG00000172680 ENSG00000169291 ENSG00000111816 ENSG00000167701 PMC5136711__F1 Diagrammatic representation of the extrinsic and intrinsic apoptotic pathways ENSG00000132906 ENSG00000168040 ENSG00000164305 ENSG00000026103 PMC12130507__F4 KEGG pathway “Regulation of lipolysis”, significantly associated with CD36 abundance ENSG00000105664 ENSG00000183760 ENSG00000171105 ENSG00000187288 ENSG00000165409 PMC10672452__F1 LPS-induced inflammatory response of the innate immune system and the anti-inflammatory effect of LPS-binding peptides/proteins from marine invertebrates ENSG00000170458 ENSG00000172936 PMC9122124__F2 Macrophage: A Cell With Many Faces and Functions in Tuberculosis ENSG00000169245 ENSG00000081181 ENSG00000002330 ENSG00000115415 ENSG00000163739 ENSG00000138755 ENSG00000136869 ENSG00000168610 ENSG00000136826 PMC5225790__F13 VEGF/VEGFR signalling pathway in normal vs ENSG00000186575 ENSG00000118257 ENSG00000075213 PMC8836075__F2 Aryl Hydrocarbon Receptor (AHR): A Novel Therapeutic Target for Pulmonary Diseases? ENSG00000181019 ENSG00000291971 ENSG00000106546 PMC7914659__F1 Three major sources of H2S: enzymatic pathway, nonenzymatic pathway, and bacterial origins PMC5626595__F1 ANTAGONISM OF TYPE I INTERFERON BY FLAVIVIRUSES ENSG00000135655 ENSG00000213928 ENSG00000164430 ENSG00000088888 ENSG00000187608 ENSG00000157601 ENSG00000121060 ENSG00000142166 PMC5626595__F2 ANTAGONISM OF TYPE I INTERFERON BY FLAVIVIRUSES ENSG00000213928 ENSG00000164430 ENSG00000088888 ENSG00000187608 ENSG00000115415 ENSG00000113595 ENSG00000127481 ENSG00000157601 ENSG00000276561 ENSG00000142166 PMC5056327__F1 Phosphatidylinositol 3 kinase/Akt pathway ENSG00000177455 ENSG00000002330 ENSG00000169047 PMC5225790__F11 Childhood neurofibromatosis type 2 (NF2) and related disorders: from bench to bedside and biologically targeted therapies ENSG00000157764 ENSG00000115904 ENSG00000168938 ENSG00000166068 ENSG00000108061 PMC3047086__F9 Suggested modes of the involvement of Nrf2/ARE in the regulation of AML cell differentiation ENSG00000178573 ENSG00000177606 ENSG00000079999 PMC10604902__F1 Oxidative stress from dysregulated NOX activation and mitochondrial dysfunction regulates the signaling pathways involved in initiating and maintaining AF ENSG00000163739 ENSG00000086991 ENSG00000026508 ENSG00000198626 ENSG00000168610 PMC6202553__F4 Gene networks ENSG00000087245 ENSG00000157404 ENSG00000107562 ENSG00000069482 ENSG00000038427 ENSG00000065361 ENSG00000134853 ENSG00000167653 ENSG00000171791 ENSG00000077782 ENSG00000115461 ENSG00000104368 PMC9584359__F2 EBV-driven 1C pathway drives nucleotide and glutathione synthesis ENSG00000065911 ENSG00000100714 ENSG00000092621 ENSG00000164466 ENSG00000135069 ENSG00000146733 ENSG00000164933 ENSG00000120254 PMC11880705__F3 NS1 in counteracting innate immunity1: Binding of NS1 to p85Beta-SH2 relieved p85B repression of p110a, activated PI3/Akt signaling, and inhibited the apoptotic program induced by influenza virus ENSG00000089127 ENSG00000135828 ENSG00000121060 PMC4702030__F4 A - Ingenuity pathway analysis of genes involved in human epithelial ovarian cancer (EOCs) and other associated diseases that have overlapping pathways ENSG00000149311 ENSG00000139687 ENSG00000196712 ENSG00000183765 PMC11885102__F4 Schematic diagram of the regulation of intestinal ACE2 on islet function ENSG00000257008 ENSG00000130234 PMC5642919__F5 Proposed model ENSG00000136694 PMC7758911__F1 RTKs and ERA36 in the development of tamoxifen resistance ENSG00000108691 ENSG00000198793 ENSG00000146648 PMC9424771__F8 Molecular mechanism of Epimedium in the treatment of vascular dementia based on network pharmacology and molecular docking ENSG00000167207 ENSG00000007908 ENSG00000168040 ENSG00000127191 ENSG00000164305 ENSG00000172216 ENSG00000157227 ENSG00000196549 ENSG00000149968 ENSG00000078747 ENSG00000177606 ENSG00000056558 ENSG00000131323 PMC6462522__F9 BIN1 loss enables ATM activation by the nuclear protein E2F1 ENSG00000149311 PMC6116613__F3 MITOCHONDRIAL DYNAMICS AND METABOLIC REGULATION IN CARDIAC AND SKELETAL MUSCLE ENSG00000128272 ENSG00000105550 PMC11859690__F2 Action of anti-HER2 drugs ENSG00000134982 ENSG00000198793 PMC11860879__F1 Signaling pathways in the immune TME in AOC ENSG00000081041 ENSG00000111837 ENSG00000127191 ENSG00000168610 PMC11860879__F2 Multiple signaling pathways in the non-immune TME in AOC ENSG00000149311 ENSG00000175054 ENSG00000169291 ENSG00000198793 ENSG00000123191 ENSG00000168036 ENSG00000291761 ENSG00000146648 PMC4136812__F4 Insulin, CCAAT/Enhancer-Binding Proteins and Lactate Regulate the Human 11Beta-Hydroxysteroid Dehydrogenase Type 2 Gene Expression in Colon Cancer Cell Lines ENSG00000169047 ENSG00000198793 ENSG00000106624 ENSG00000176387 PMC7903415__F1 The signaling pathways in LF by lncRNAs ENSG00000168036 PMC11860879__F4 Applications of NPs to reverse the non-immune TME in AOC ENSG00000012048 ENSG00000214285 ENSG00000291761 PMC3733544__F7 FA/BRCA DNA damage response pathway ENSG00000012048 ENSG00000136492 ENSG00000083093 ENSG00000077152 ENSG00000162607 ENSG00000139618 PMC9321592__F6 IL‐20 promotes cutaneous inflammation and peripheral itch sensation in atopic dermatitis ENSG00000108691 ENSG00000078747 ENSG00000163739 ENSG00000146469 PMC9197867__F2 Osteoprotegerin and RANKL-RANK-OPG-TRAIL signalling axis in heart failure and other cardiovascular diseases ENSG00000124102 ENSG00000112715 PMC408106__F1 Partial synthesis pathway of GSLs ENSG00000049860 PMC11880705__F5 Applications of live attenuated influenza a virus with modified NS1 gene ENSG00000276561 ENSG00000164342 PMC4541706__F1 The unfolded protein response ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8507154__F2 Current knowledge and challenges associated with targeted delivery of neurotrophic factors into the central nervous system: focus on available approaches ENSG00000291971 ENSG00000010810 PMC4671996__F4 Transcription factors and genes that regulate PDKs regulation ENSG00000198793 ENSG00000136997 PMC4853752__F1 MicroRNA network that is involved in regulating myogenesis ENSG00000100811 ENSG00000009709 ENSG00000281766 ENSG00000170365 ENSG00000111049 ENSG00000198793 ENSG00000185591 ENSG00000124795 ENSG00000077782 PMC4671996__F2 Illustration of Warburg effect in cancer cells PMC7775721__F2 Genetic defects in the sphingolipid degradation pathway and their effects on microglia in neurodegenerative disease ENSG00000170266 ENSG00000213614 ENSG00000049860 PMC9099719__F2 Tumour Stem Cells in Breast Cancer ENSG00000108691 ENSG00000107562 ENSG00000188404 ENSG00000079432 ENSG00000057663 PMC12112599__F7 Images of the protein processing in the endoplasmic reticulum pathways enriched among the imported differentially expressed genes (DEGs) identified from the lipopolysaccharide (LPS) vs ENSG00000291983 ENSG00000128272 ENSG00000008952 ENSG00000113558 ENSG00000188404 ENSG00000076641 ENSG00000198168 PMC7775721__F1 Genetic defects in the sphingolipid degradation pathway and their effects on microglia in neurodegenerative disease ENSG00000170266 ENSG00000119655 ENSG00000213614 ENSG00000141458 ENSG00000049860 PMC9099719__F1 Tumour Stem Cells in Breast Cancer ENSG00000198793 ENSG00000168036 PMC6059371__F1 Function of Hsp70 in suppressing apoptosis after ischemic stroke ENSG00000132906 ENSG00000168040 ENSG00000064012 ENSG00000164305 PMC4987408__F3 Regulation of rhein on the crosstalk of MAPK signaling pathway ENSG00000087095 ENSG00000042832 ENSG00000128052 PMC10895590__F6 Immunorecognition of RNA/DNA fiber NANPs via the cGAS-STING signaling pathway can be regulated through functionalization with aptamers ENSG00000183735 ENSG00000164430 PMC4839494__F2 Adenosine receptor-mediated signaling pathways ENSG00000170425 PMC6412520__F1 Simplified diagram of methionine metabolism (adapted from ) PMC5924476__F1 Mutations in CYB561 Causing a Novel Orthostatic Hypotension Syndrome ENSG00000008283 ENSG00000123454 ENSG00000141744 PMC1602337__F9 TWEAK-Fn14 signaling system may play a role in stroke pathophysiology ENSG00000082512 ENSG00000056558 ENSG00000131323 ENSG00000127191 PMC6315862__F2 Overview of the DSB repair mechanisms PMC12199384__F1 Core‐shell manganese phosphate nanomodulator enhances anti‐tumor immunotherapy via bidirectional reprogramming of the tumor microenvironment ENSG00000196839 ENSG00000026508 ENSG00000189403 PMC4749490__F1 Hypothesis: central neuroendocrine and peripheral mechanisms in generation of sex bias in PH ENSG00000171759 PMC8944072__F3 Protein interaction networks provide insight into fetal origins of chronic obstructive pulmonary disease ENSG00000070831 ENSG00000157601 ENSG00000146648 ENSG00000197702 PMC7352357__F1 Cholesterol metabolism and key oncogenic pathways related to cancer development ENSG00000162711 ENSG00000130164 ENSG00000113161 ENSG00000186480 ENSG00000104549 ENSG00000128602 ENSG00000168610 ENSG00000075239 ENSG00000169174 PMC9001073__F6 Isoflurane Attenuates Cerebral Ischaemia–Reperfusion Injury via the TLR4-NLRP3 Signalling Pathway in Diabetic Mice ENSG00000162711 ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC6199630__F6 Targeted and Off-Target (Bystander and Abscopal) Effects of Radiation Therapy: Redox Mechanisms and Risk/Benefit Analysis ENSG00000149311 ENSG00000012048 PMC3973632__F5 Integrated Analysis of Copy Number Variation and Genome-Wide Expression Profiling in Colorectal Cancer Tissues ENSG00000145604 ENSG00000094804 ENSG00000132646 ENSG00000135336 ENSG00000123374 ENSG00000277273 ENSG00000117399 ENSG00000276876 ENSG00000093009 PMC11670821__F1 Generation and release of exosomes in response to bacterial infection ENSG00000074319 ENSG00000010278 ENSG00000135404 ENSG00000123908 PMC11670821__F3 Immune responses mediated by (H) pylori OMVs and infected cell exosomes ENSG00000110651 ENSG00000172936 ENSG00000136869 ENSG00000135404 PMC11670821__F5 Roles of H. pylori OMVs and infected cell exosomes in the extra-gastric diseases ENSG00000165556 ENSG00000127528 ENSG00000142405 ENSG00000162692 ENSG00000168610 PMC6016889__F1 CLL main pathogenic pathways and target agents against BTK, PI3K and Bcl-2 ENSG00000177455 ENSG00000107562 ENSG00000169071 ENSG00000148400 ENSG00000186716 ENSG00000198793 ENSG00000185483 ENSG00000197943 ENSG00000010671 ENSG00000121966 PMC5366100__F2 Regulation of NOX by H ENSG00000124479 ENSG00000140279 ENSG00000140274 ENSG00000105402 ENSG00000188747 PMC8579447__F8 PiRNA-63049 inhibits bone formation through Wnt/Beta-catenin signaling pathway ENSG00000110711 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000134245 PMC6571165__F1 Signaling pathways that modulate cardioprotection in CMs ENSG00000179862 PMC6571165__F2 Signaling pathways that contribute to CF activation and stress response ENSG00000141867 ENSG00000146648 PMC3345255__F1 MAPK/ERK signaling and the hallmarks of cancers ENSG00000002330 ENSG00000138798 ENSG00000198793 PMC12084948__F2 Signaling networks downstream of SLAMF receptors in regulating immune cells ENSG00000291971 ENSG00000026751 ENSG00000166278 ENSG00000141968 PMC3926884__F1 Identification of a KRAS mutation in a patient with non-small cell lung cancer treated with chemoradiotherapy and panitumumab ENSG00000169291 ENSG00000109321 ENSG00000198793 ENSG00000113520 ENSG00000146648 PMC2958210__F12 Selective populations of hippocampal interneurons express ErbB4 and their number and distribution is altered in ErbB4 knockout mice ENSG00000164879 ENSG00000173599 ENSG00000197429 PMC12084948__F4 SLAMF receptors modulate cancer progression ENSG00000108691 ENSG00000158714 ENSG00000026751 PMC10506410__F3 Vitamin D receptor deficiency may induce alopecia through the Ddit4/mTOR signaling pathway ENSG00000168209 ENSG00000168487 PMC9468787__F1 Nexus of lipid and O-Glcnac metabolism in physiology and disease ENSG00000147162 ENSG00000198408 ENSG00000100219 ENSG00000026103 PMC10506410__F1 MTOR Signaling Network (A) Overview of the mTOR signaling pathway (B–D) mTORC1 signaling in mRNA translation, metabolism, and protein turnover (E) mTORC2 signaling function ENSG00000177169 ENSG00000065911 ENSG00000198382 ENSG00000128272 ENSG00000177058 ENSG00000150907 ENSG00000145979 ENSG00000112561 ENSG00000146648 ENSG00000196712 ENSG00000084774 PMC8405566__F3 Candidate model for Ccr4-Not mediated nutrient signaling ENSG00000278494 ENSG00000101751 ENSG00000143761 PMC7075943__F1 Predicted lipid synthesis pathways of phospholipids in E ENSG00000124102 ENSG00000173599 ENSG00000184207 PMC8178461__F1 Roles of PD-1/PD-L1 in the prognosis and immunotherapy of prostate cancer ENSG00000168036 ENSG00000128342 ENSG00000168610 ENSG00000120256 PMC7291472__F1 Diagram of CD155/CD112-mediated immunoregulatory pathway on NK cells ENSG00000153283 ENSG00000181847 ENSG00000150637 PMC8511527__F1 Endoplasmic Reticulum Quality Control in Immune Cells ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC4032983__F6 CK1 in Wnt-signaling ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000168036 ENSG00000197555 PMC4032983__F8 CK1 in Hippo signaling in vertebrates ENSG00000186575 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC9315518__F10 Identification and Functional Analysis of Individual-Specific Subpathways in Lung Adenocarcinoma ENSG00000165556 ENSG00000118007 ENSG00000108055 ENSG00000179091 ENSG00000112118 ENSG00000091651 ENSG00000277273 ENSG00000117399 ENSG00000166508 ENSG00000276876 ENSG00000093009 ENSG00000145604 ENSG00000094804 ENSG00000101972 ENSG00000132646 ENSG00000115942 ENSG00000123374 PMC6134416__F1 小细胞肺癌的的分子发病机制 ENSG00000135446 ENSG00000123374 PMC12006098__F10 Galangin attenuated MPTP-induced brain tissue injury in PD model mice, and the related mechanism may be related to the PI3K/AKT signaling pathway ENSG00000198793 PMC4107035__F2 PATHOGENETIC MECHANISMS OF FOCAL CORTICAL DYSPLASIA ENSG00000266173 ENSG00000198793 ENSG00000124356 ENSG00000196712 PMC6134416__F3 在SCLC中，受体酪氨酸激酶及其配体通常呈过表达状态。缺陷性受体酪氨酸激酶及它们各自的生长因子包括：VEGFR/VEGF, c-Kit/SCF, c-MET/HGF, FGFR/FGF以及IGF-1R/IGF。通过多种通路的激活，包括在SCLC中失调的PI3K/AKT/mTOR通路，在存活、凋亡、细胞周期调节和翻译过程中发挥作用。Receptor tyrosine kinases and their known ligands are often overexpressed in SCLC ENSG00000019991 ENSG00000198793 ENSG00000140443 PMC8965611__F5 Signaling Pathways Associated With Breast Cancer Bone Metastasis ENSG00000281324 ENSG00000291971 ENSG00000078579 ENSG00000198793 ENSG00000177606 ENSG00000156427 ENSG00000136997 ENSG00000168036 ENSG00000175104 PMC4107035__F3 PATHOGENETIC MECHANISMS OF FOCAL CORTICAL DYSPLASIA ENSG00000266173 ENSG00000198793 ENSG00000124356 ENSG00000196712 PMC2151841__F4 Signal transduction pathway in the UPR ENSG00000128272 ENSG00000127191 PMC5971224__F1 Fatty acid (FA) and ceramide synthetic pathway in autosomal recessive congenital ichthyosis converge on the corneocyte lipid envelope (CLE) ENSG00000179148 ENSG00000204020 ENSG00000179477 ENSG00000118402 ENSG00000042832 ENSG00000072210 ENSG00000154227 ENSG00000164751 ENSG00000062282 PMC4319960__F7 SMAD-Independent Down-Regulation of Caveolin-1 by TGFB: Effects on Proliferation and Survival of Myofibroblasts PMC83966__F7 Ras effector pathways in NGF stimulated PC12 cells ENSG00000124102 ENSG00000070831 PMC7464644__F3 Role of Tumor-Associated Myeloid Cells in Breast Cancer ENSG00000118520 ENSG00000100985 ENSG00000168610 PMC7464644__F2 Role of Tumor-Associated Myeloid Cells in Breast Cancer ENSG00000275385 ENSG00000116106 ENSG00000163739 ENSG00000138798 ENSG00000148926 ENSG00000184371 ENSG00000187764 ENSG00000118520 ENSG00000168610 ENSG00000146648 PMC8489191__F1 Post-translational modification control of viral DNA sensors and innate immune signaling ENSG00000122566 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000163568 ENSG00000163565 ENSG00000168036 ENSG00000174953 ENSG00000172936 PMC12145212__F9 Mechanisms by which hypoxia impairs spermatogonial proliferation ENSG00000135446 ENSG00000105810 PMC12029571__F4 UPR pathway ENSG00000128272 ENSG00000100219 ENSG00000127191 PMC7155770__F4 Death receptor pathway of apoptosis ENSG00000104856 ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC12029571__F1 Main metabolic pathways involved in cancer ENSG00000157184 ENSG00000136997 ENSG00000115419 PMC12029571__F2 Main metabolic pathways involved in cancer ENSG00000157184 ENSG00000042832 ENSG00000169710 ENSG00000099194 PMC7155770__F3 Mitochondrial pathway of apoptosis ENSG00000120868 ENSG00000115317 PMC7906172__F9 ADSCs promote functional recovery after spinal cord injury by activating the TGFB1/Smad3/PLOD2 signaling pathway ENSG00000152952 PMC5617400__F4 Autophagy-related gene expression is an independent prognostic indicator of glioma ENSG00000152348 ENSG00000097033 ENSG00000198382 ENSG00000126775 ENSG00000050748 ENSG00000198793 ENSG00000205250 ENSG00000049768 ENSG00000154447 ENSG00000125347 ENSG00000173327 ENSG00000057663 ENSG00000124782 ENSG00000132170 ENSG00000071564 ENSG00000144848 ENSG00000168310 ENSG00000145782 ENSG00000179348 ENSG00000102974 PMC9656839__F8 High-Resolution Crystal Structure of Muscle Phosphoglycerate Mutase Provides Insight into Its Nuclear Import and Role ENSG00000169047 ENSG00000198793 ENSG00000164708 ENSG00000140443 PMC3132733__F1 Pathway-Based Association Analyses Identified TRAIL Pathway for Osteoporotic Fractures ENSG00000131323 ENSG00000168040 PMC6477898__F4 Peripheral Blood DNA Methylation Signature of Hepatic Fat Reveals a Potential Causal Pathway for Nonalcoholic Fatty Liver Disease ENSG00000015285 ENSG00000160179 PMC9290759__F2 Association of Gut Microbiota and Treg Dysfunction in Autoimmune Diseases ENSG00000106546 PMC9701576__F3 Racial disparities in prostate cancer: A complex interplay between socioeconomic inequities and genomics ENSG00000157554 ENSG00000134982 ENSG00000130675 ENSG00000105516 ENSG00000184012 ENSG00000169710 ENSG00000168036 ENSG00000129514 ENSG00000159788 PMC9528914__F1 Polycystic Liver Disease: Pathophysiology, Diagnosis and Treatment ENSG00000157764 ENSG00000134982 ENSG00000173599 PMC7541127__F4 Landscape of major pathway alterations in primary GBM ENSG00000157764 ENSG00000135446 ENSG00000134853 ENSG00000105810 ENSG00000146648 ENSG00000139687 ENSG00000196712 ENSG00000198625 PMC10705747__F6 CBD’s neuroprotective mechanism in ABeta-induced impairments ENSG00000030582 ENSG00000158714 ENSG00000109861 ENSG00000197943 PMC9495798__F9 Physiological and Comparative Transcriptome Analysis Reveals the Mechanism by Which Exogenous 24-Epibrassinolide Application Enhances Drought Resistance in Potato (Solanum tuberosum L.) ENSG00000110934 ENSG00000015285 PMC11281541__F10 Hypothetical schema of the protective role of MIN in TBEV-infected Vero cells ENSG00000132718 ENSG00000198626 ENSG00000146648 ENSG00000132639 PMC3821994__F1 PI3K/AKT/mTOR signaling pathway showing interacting activation and regulatory feedback loops ENSG00000198793 ENSG00000284161 ENSG00000167658 ENSG00000164327 PMC3004523__F2 Hypothetical roles for LAB-dependent positive signaling ENSG00000157404 ENSG00000033327 ENSG00000010810 ENSG00000164399 PMC4841221__F1 Changes to coral health and metabolic activity under oxygen deprivation ENSG00000110711 ENSG00000039537 ENSG00000166278 PMC6481742__F1 Schematic representation of the major components of the endosomal pathway and the generation of exosomes ENSG00000272398 ENSG00000074319 ENSG00000110651 ENSG00000010278 ENSG00000164176 ENSG00000135404 ENSG00000146648 PMC3975402__F2 Apoptosis pathway ENSG00000002330 ENSG00000120868 ENSG00000168040 PMC5264260__F2 Intracellular signaling pathways of A7nAchR in anti-inflammatory response ENSG00000125538 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC9472579__F1 Insights into pandemic respiratory viruses: manipulation of the antiviral interferon response by SARS-CoV-2 and influenza A virus ENSG00000183735 ENSG00000164430 ENSG00000187608 ENSG00000089127 ENSG00000115415 ENSG00000121060 ENSG00000164342 PMC4576457__F7 Hypothalamic PKA regulates leptin sensitivity and adiposity ENSG00000115138 ENSG00000168610 PMC8509318__F2 Chronic and Cycling Hypoxia: Drivers of Cancer Chronic Inflammation through HIF-1 and NFKB Activation: A Review of the Molecular Mechanisms ENSG00000181788 ENSG00000158050 PMC9530862__F2 Effect of fasting on cancer: A narrative review of scientific evidence ENSG00000198793 ENSG00000005893 ENSG00000096717 PMC12024365__F8 Diagram of PPAR signaling pathway ENSG00000099194 ENSG00000124253 PMC9709415__F3 Protective effect of natural medicines against excessive inflammation and oxidative stress in acute lung injury by regulating the Nrf2 signaling pathway ENSG00000181019 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000079999 PMC2994272__F8 Carnosol in human prostate cancer PC3 cell line ENSG00000198793 PMC5862044__F1 Nutrition and fasting mimicking diets in the prevention and treatment of autoimmune diseases and immunosenescence ENSG00000198793 ENSG00000136997 PMC9709415__F1 Protective effect of natural medicines against excessive inflammation and oxidative stress in acute lung injury by regulating the Nrf2 signaling pathway ENSG00000178573 ENSG00000079999 PMC7363928__F8 Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling ENSG00000163739 ENSG00000136869 PMC4631823__F1 Model for brassinosteroid (BR) signaling pathway in the absence and in the presence of BR ENSG00000110934 ENSG00000163166 PMC4842059__F3 Id2 network model in insulin signaling, thermogenesis, and adipogenesis pathways ENSG00000122691 ENSG00000142611 ENSG00000169710 ENSG00000079435 PMC10912430__F6 Signaling pathways that may be triggered by cellular autophagy during intestinal I/R ENSG00000177169 ENSG00000160703 ENSG00000069509 ENSG00000265972 PMC10912430__F4 Signaling pathways that may be triggered by cellular pyroptosis during intestinal I/R ENSG00000162711 ENSG00000137275 ENSG00000136869 ENSG00000265972 ENSG00000146648 ENSG00000285379 PMC5337147__F2A Post-transcriptional regulation of cytokine and growth factor signaling in cancer ENSG00000019991 ENSG00000002330 ENSG00000105329 ENSG00000138798 ENSG00000198793 ENSG00000170558 ENSG00000288335 ENSG00000100744 ENSG00000166278 ENSG00000112715 ENSG00000149187 ENSG00000168610 ENSG00000136603 ENSG00000066044 ENSG00000198742 ENSG00000146648 PMC8478533__F3 Crosstalk between Heart Failure and Cognitive Impairment via hsa-miR-933/RELB/CCL21 Pathway ENSG00000188786 ENSG00000002330 ENSG00000070831 ENSG00000126756 ENSG00000087586 ENSG00000265972 ENSG00000277571 ENSG00000239732 ENSG00000088888 ENSG00000188404 ENSG00000170430 ENSG00000130402 ENSG00000179094 ENSG00000101425 ENSG00000125755 ENSG00000123096 ENSG00000105698 ENSG00000099194 ENSG00000087460 ENSG00000108839 ENSG00000108582 ENSG00000117036 ENSG00000166478 ENSG00000170458 ENSG00000124882 ENSG00000137077 ENSG00000185129 ENSG00000084774 ENSG00000130726 PMC9437486__F6 Astragaloside IV attenuates ferroptosis after subarachnoid hemorrhage via Nrf2/HO-1 signaling pathway ENSG00000151012 ENSG00000167468 ENSG00000079999 PMC10912430__F5 Signaling pathways that may be triggered by cellular ferroptosis during intestinal I/R ENSG00000151012 ENSG00000167468 ENSG00000164362 ENSG00000196689 PMC8880424__F6 Multi-Omic Analysis to Characterize Metabolic Adaptation of the E. coli Lipidome in Response to Environmental Stress ENSG00000113600 ENSG00000184207 PMC8183045__F8 Site-directed mutagenesis of the quorum-sensing transcriptional regulator SinR affects the biosynthesis of menaquinone in Bacillus subtilis ENSG00000133895 ENSG00000159224 ENSG00000197429 PMC10912430__F3 Signaling pathways that may be triggered by cellular apoptosis and necrosis during intestinal I/R ENSG00000008710 ENSG00000127445 ENSG00000171720 ENSG00000158828 ENSG00000131323 ENSG00000142082 ENSG00000026103 PMC9434120__F1 Relationship between metabolic reprogramming and drug resistance in breast cancer ENSG00000180210 ENSG00000042832 ENSG00000213658 ENSG00000136997 ENSG00000169710 ENSG00000146733 ENSG00000105552 ENSG00000115419 PMC9434120__F2 Relationship between metabolic reprogramming and drug resistance in breast cancer ENSG00000198793 ENSG00000150093 ENSG00000168036 PMC7516048__F2 Model for B. pertussis CyaA regulated complex signaling pathways to block the monocyte differentiation and to trigger macrophage dedifferentiation ENSG00000150457 ENSG00000131023 PMC10912430__F1 Signaling pathways that may be triggered by cellular oxidation or inflammation during intestinal I/R ENSG00000181019 ENSG00000131323 ENSG00000077463 ENSG00000142082 PMC3078450__F5 Network annotation of genes differentially expressed according to the CD133 status in HT-29 using ingenuity pathway analyses ENSG00000154342 ENSG00000168283 ENSG00000041982 ENSG00000134982 ENSG00000168036 ENSG00000077782 ENSG00000157212 PMC9688046__F2 USP7 Inhibitors in Cancer Immunotherapy: Current Status and Perspective ENSG00000049768 PMC8065217__F1 Spatiotemporal regulation of hydrogen sulfide signaling in the kidney PMC6443339__F12 Regulatory effects of H2S on PCSK9 expression and lipid metabolism ENSG00000130164 ENSG00000169174 PMC9317282__F12 Comparative Transcriptome and Interaction Protein Analysis Reveals the Mechanism of IbMPK3-Overexpressing Transgenic Sweet Potato Response to Low-Temperature Stress ENSG00000105722 ENSG00000136997 PMC4125416__F2 Adaptive immunity with Toll-like receptors ENSG00000198793 ENSG00000172936 ENSG00000175104 ENSG00000276561 PMC9146250__F3 New Insights into Hematopoietic Stem Cell Expansion to Stimulate Repopulation of the Adult Blood System for Transplantation ENSG00000090534 ENSG00000156983 ENSG00000291971 ENSG00000198793 ENSG00000198125 ENSG00000174059 ENSG00000106546 PMC6450748__F10 Ethanol induces hyperacetylation and hyposuccinylation of mitochondrial proteins involved in diverse metabolic pathways ENSG00000125166 ENSG00000284807 ENSG00000143158 ENSG00000171503 ENSG00000140740 ENSG00000073578 ENSG00000131495 ENSG00000099624 ENSG00000157184 ENSG00000167107 ENSG00000112304 ENSG00000124172 ENSG00000173599 ENSG00000119013 ENSG00000036473 ENSG00000075239 ENSG00000146701 ENSG00000091140 ENSG00000105379 ENSG00000126432 PMC8925223__F1 DHCR24 in the pathogenesis of AD: re-cognition of the relationship between cholesterol and AD pathogenesis ENSG00000116133 ENSG00000172893 ENSG00000109929 ENSG00000113161 PMC10030580__F2 Macrophages in aseptic loosening: Characteristics, functions, and mechanisms ENSG00000162711 ENSG00000226275 ENSG00000125538 ENSG00000198793 ENSG00000172936 ENSG00000157625 ENSG00000175104 PMC4835794__F2 Hibernating South American marsupial, Dromiciops gliroides, displays torpor-sensitive microRNA expression patterns ENSG00000175634 ENSG00000168209 ENSG00000117020 ENSG00000083290 ENSG00000266173 ENSG00000162409 ENSG00000169047 ENSG00000135932 PMC4835794__F3 Hibernating South American marsupial, Dromiciops gliroides, displays torpor-sensitive microRNA expression patterns ENSG00000140992 ENSG00000117020 ENSG00000157764 ENSG00000266173 ENSG00000169047 ENSG00000135932 ENSG00000132356 PMC8799702__F5 Protein tyrosine phosphatases in skeletal development and diseases ENSG00000152266 ENSG00000170365 ENSG00000111341 ENSG00000168036 ENSG00000168610 ENSG00000204217 PMC4981357__F7 Chronic Inhibition of STAT3/STAT5 in Treatment-Resistant Human Breast Cancer Cell Subtypes: Convergence on the ROS/SUMO Pathway and Its Effects on xCT Expression and System xc- Activity ENSG00000142230 ENSG00000126261 ENSG00000168610 PMC11748936__F7 SIGLEC11 promotes M2 macrophage polarization through AKT–mTOR signaling and facilitates the progression of gastric cancer ENSG00000105329 ENSG00000161640 ENSG00000198793 PMC8889706__F8 LOX-1 receptor ectopically expressed in the liver alleviates atherosclerosis by clearing Ox-LDL from the circulation ENSG00000138075 ENSG00000130164 ENSG00000143921 PMC8496081__F5 Genetic and epigenetic associations of ANRIL with coronary artery disease and risk factors ENSG00000276463 ENSG00000147133 PMC6159521__F4 Schematic drawing of the asymmetric specificity of the EndoMS-dependent MMR system and asymmetric occurrence of replication errors ENSG00000145321 PMC11430996__F4 Effect of anthocyanin on initiating apoptosis in human colon cancer line ENSG00000002330 ENSG00000026103 PMC8606538__F1 Aberrant Cholesterol Metabolism in Ovarian Cancer: Identification of Novel Therapeutic Targets ENSG00000057252 ENSG00000130164 ENSG00000163914 ENSG00000113161 ENSG00000104549 ENSG00000160179 PMC6033520__F1 Hedgehog pathway in nonalcoholic fatty liver disease ENSG00000173599 ENSG00000164399 ENSG00000128602 PMC3137639__F5 Akt-RSK-S6-kinase Signaling Networks Activated by Oncogenic Receptor Tyrosine Kinases ENSG00000155506 ENSG00000002330 ENSG00000077235 ENSG00000101079 ENSG00000136111 ENSG00000169047 ENSG00000198793 ENSG00000164327 ENSG00000198087 ENSG00000136153 ENSG00000079950 ENSG00000196914 ENSG00000142627 ENSG00000140262 ENSG00000104969 ENSG00000213390 ENSG00000060237 ENSG00000179151 ENSG00000144224 ENSG00000165795 ENSG00000146834 ENSG00000071564 ENSG00000066468 ENSG00000067066 ENSG00000165632 ENSG00000127481 ENSG00000117758 ENSG00000204673 ENSG00000134853 ENSG00000185033 ENSG00000139116 ENSG00000163166 ENSG00000184708 ENSG00000146648 ENSG00000105723 ENSG00000164830 ENSG00000105821 PMC6714586__F1 Main signaling pathways implicated in VE-cadherin/VM-positive cells ENSG00000084774 PMC3976810__F2 Molecular pathways are altered due to modulation of signaling pathway in skin cancer ENSG00000132646 ENSG00000005381 ENSG00000064012 ENSG00000164305 PMC7816290__F10 Schematic summary demonstrating the molecular mechanism of anti-ALR McAb inhibiting the proliferation of U266 cells ENSG00000168610 PMC4516482__F7 The hypothetical mechanisms involved in fibronectin-induced P2X4R up-regulation in microglia PMC7018659__F8 Possible mechanism underling periodontal inflammation-induced metastasis ENSG00000162711 ENSG00000108691 ENSG00000107562 ENSG00000125538 ENSG00000136869 PMC9068916__F7 SP1-mediated oncogenic mechanism in CRC progression ENSG00000173120 ENSG00000185591 ENSG00000253352 PMC6706905__F7 Systemic diagram of the mechanism of S1PR1/STAT3 signaling pathway ENSG00000136997 ENSG00000170989 ENSG00000168610 PMC2700213__F1 Genetic variants in pigmentation genes, pigmentary phenotypes, and risk of skin cancer in Caucasians ENSG00000101440 ENSG00000115138 ENSG00000188467 ENSG00000107165 PMC8789654__F5 Anti-Hepatocellular Carcinoma Effect and Molecular Mechanism of the Estrogen Signaling Pathway ENSG00000172936 ENSG00000184216 PMC8789654__F6 Anti-Hepatocellular Carcinoma Effect and Molecular Mechanism of the Estrogen Signaling Pathway ENSG00000109321 ENSG00000291971 ENSG00000146648 ENSG00000164305 PMC8789654__F4 Anti-Hepatocellular Carcinoma Effect and Molecular Mechanism of the Estrogen Signaling Pathway ENSG00000157554 ENSG00000162711 ENSG00000151490 ENSG00000198793 ENSG00000140505 ENSG00000129514 ENSG00000185591 ENSG00000164305 PMC11012077__F2 Chemokine Fractalkine and Non-Obstructive Coronary Artery Disease—Is There a Link? ENSG00000104856 ENSG00000168329 ENSG00000173039 ENSG00000162692 PMC6015375__F6 Schematic demonstrating of [U‐13C]glucose to CAC and PPP, and protein expression levels in HBP ENSG00000147162 ENSG00000198408 ENSG00000062485 PMC9302585__F1 Extraglycemic Effect of SGLT-2is on Mineral and Bone Metabolism and Bone Fracture ENSG00000152266 ENSG00000036828 ENSG00000274348 ENSG00000119121 PMC5313050__F3 Presence of arachidonoyl-carnitine is associated with adverse cardiometabolic responses in hypertensive patients treated with atenolol ENSG00000157184 ENSG00000177465 ENSG00000026103 PMC11930710__F2 Model illustrates how resistance to EGFR-targeted drugs develops due to the loss of PTEN expression, caused by impaired nuclear translocation of EGR1 in lung cancer cells: A ENSG00000146648 PMC2889681__F1 Neurotrophic and neuroprotective pathways targeted by lithium ENSG00000002330 ENSG00000168036 PMC7603631__F6 Notoginseng Leaf Triterpenes Ameliorates OGD/R-Induced Neuronal Injury via SIRT1/2/3-Foxo3a-MnSOD/PGC-1A Signaling Pathways Mediated by the NAMPT-NAD Pathway ENSG00000105835 ENSG00000096717 ENSG00000142082 ENSG00000283100 PMC8014352__F5 Potential pathway of IGFBP-1 in the present review ENSG00000043355 ENSG00000082175 ENSG00000291971 ENSG00000175745 ENSG00000169047 ENSG00000198793 ENSG00000146678 PMC9234081__F6 Dietary cholesterol promotes growth and ecdysone signalling pathway by modulating cholesterol transport in swimming crabs (Portunus trituberculatus) ENSG00000161533 ENSG00000026103 PMC8834563__F2 Enhanced Loss of Retinoic Acid Network Genes in Xenopus laevis Achieves a Tighter Signal Regulation ENSG00000111012 ENSG00000132196 ENSG00000205221 ENSG00000001630 ENSG00000116133 ENSG00000172893 ENSG00000149809 ENSG00000105516 ENSG00000019186 ENSG00000104549 ENSG00000186104 ENSG00000135929 PMC9220817__F1 Blood Cell-Derived Microvesicles in Hematological Diseases and beyond ENSG00000177455 ENSG00000170458 ENSG00000026508 ENSG00000010278 ENSG00000005381 PMC8923803__F9 Identification of IL20RB as a Novel Prognostic and Therapeutic Biomarker in Clear Cell Renal Cell Carcinoma ENSG00000185436 ENSG00000173039 ENSG00000291876 ENSG00000243646 ENSG00000110324 ENSG00000049768 ENSG00000105639 ENSG00000162892 ENSG00000146648 ENSG00000174564 ENSG00000291875 ENSG00000016402 PMC9097137__F2 Current Insights Into Oligodendrocyte Metabolism and Its Power to Sculpt the Myelin Landscape ENSG00000197971 ENSG00000205927 PMC3314677__F9 Induction of Apoptosis Coupled to Endoplasmic Reticulum Stress in Human Prostate Cancer Cells by n-butylidenephthalide ENSG00000123374 ENSG00000127191 ENSG00000064012 ENSG00000164305 PMC2657476__F1 ErbB Receptors in the Biology and Pathology of the Aerodigestive Tract ENSG00000002330 ENSG00000291971 ENSG00000171791 ENSG00000168610 ENSG00000146648 PMC5370034__F6 Resveratrol induces cell cycle arrest and apoptosis with docetaxel in prostate cancer cells via a p53/ p21WAF1/CIP1 and p27KIP1 pathway ENSG00000132646 ENSG00000123374 PMC9476742__F4 Emerging therapeutic role of Prunella vulgaris in thyroid disease ENSG00000102871 ENSG00000105401 ENSG00000083799 ENSG00000127191 ENSG00000164305 PMC5640159__F1 Overview of the role of CtIP in the cellular response to DSB damage ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000123374 PMC9313013__F1 Molecular Basis of Rare Diseases Associated to the Maturation of Mitochondrial [4Fe-4S]-Containing Proteins ENSG00000121897 ENSG00000267673 ENSG00000109519 ENSG00000161513 ENSG00000164284 ENSG00000169599 ENSG00000135070 PMC4118498__F1 Clinical Reasoning: A 20-year-old woman with rapidly progressive weakness ENSG00000110711 ENSG00000256269 ENSG00000198125 PMC6245662__F6 Monoamine Oxidase Isoenzymes: Genes, Functions and Targets for Behavior and Cancer Therapy ENSG00000122691 ENSG00000112715 PMC3136693__F1 Chemical heme biosynthesis pathway ENSG00000144410 ENSG00000144857 ENSG00000126088 ENSG00000188690 PMC7263378__F4 Synchronized redox regulation of cysteine residues throughout canonical EGF signaling pathways at 15 and 30 minutes ENSG00000087245 ENSG00000002330 ENSG00000134982 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000184661 ENSG00000172239 ENSG00000168036 ENSG00000165527 ENSG00000102034 ENSG00000163914 ENSG00000196352 ENSG00000146648 ENSG00000084774 PMC5908849__F5 Metabolic and regulatory network of G ENSG00000197713 ENSG00000213658 ENSG00000111816 ENSG00000102977 PMC7553623__F2 K-RAS pathway in cancer development ENSG00000138798 ENSG00000146648 PMC4060285__F6 Schematic showing the protein acetylation sites in metabolic pathways that are most differentially acetylated in LDKO/flox liver ENSG00000262785 ENSG00000073578 ENSG00000138029 ENSG00000111713 ENSG00000103150 ENSG00000169710 ENSG00000163541 ENSG00000105953 ENSG00000074800 ENSG00000100412 ENSG00000115361 ENSG00000100504 ENSG00000164708 ENSG00000122971 ENSG00000100294 ENSG00000136872 ENSG00000146701 ENSG00000091140 ENSG00000159399 ENSG00000169299 ENSG00000123983 ENSG00000062485 PMC6533081__F8 Proposed model of the regulation of erythropoiesis by heme and the HRI-ISR pathway during ID ENSG00000128272 ENSG00000106070 ENSG00000169136 PMC9085237__F1 Wild type and gain of function mutant TP53 can regulate the sensitivity of pancreatic cancer cells to chemotherapeutic drugs, EGFR/Ras/Raf/MEK, and PI3K/mTORC1/GSK-3 pathway inhibitors, nutraceuticals and alter metabolic properties ENSG00000149311 ENSG00000167601 ENSG00000148400 ENSG00000291971 ENSG00000026508 ENSG00000168036 ENSG00000105810 ENSG00000168646 ENSG00000146648 ENSG00000125084 PMC4844615__F3 Pathogens-induced TLR signaling cascade in innate immune cells may exacerbate autoimmune diseases ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC11281666__F9 Deoxynivalenol and Its Acetylated Derivatives on Lipid Metabolism in Human Normal Hepatocytes ENSG00000032444 ENSG00000243708 ENSG00000125772 ENSG00000173599 ENSG00000111684 ENSG00000176485 ENSG00000133027 PMC4471389__F1 Therapeutic potential of targeting IL-17-mediated pathway ENSG00000162594 ENSG00000105397 PMC8359813__F1 Improving the Production of Riboflavin by Introducing a Mutant Ribulose 5-Phosphate 3-Epimerase Gene in Bacillus subtilis ENSG00000197713 PMC3383194__F7 The mechanism through which PTPN22 blocks proapoptotic and enhances antiapoptotic BCR signals ENSG00000095585 ENSG00000186716 ENSG00000197943 PMC9599067__F3 Clusterin Transporter in the Pathogenesis of Alzheimer’s Disease at the Blood–Brain Barrier Interface: A Systematic Review ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000133067 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC3098994__F1 Genetics of Mechanosensation in the Heart ENSG00000188554 ENSG00000022267 PMC3953715__F1 PI3K/PTEN–mTOR pathway PMC8584958__F3 Pharmacological Modulation of Ubiquitin-Proteasome Pathways in Oncogenic Signaling ENSG00000150991 PMC4022192__F5 TLR-induced signalling pathways ENSG00000174125 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000276561 PMC4551270__F6 Genome sequence-derived metabolic reconstruction of Pyrobaculum yellowstonensis strain WP30 ENSG00000168040 ENSG00000127948 ENSG00000163631 PMC8942669__F3 Histone Methylation and Oxidative Stress in Cardiovascular Diseases ENSG00000101945 ENSG00000073614 ENSG00000086991 ENSG00000185591 ENSG00000265972 ENSG00000079999 PMC7132142__F7 Schematic representation depicting the role of KMO in MM (a) pDCs trigger growth, survival, and drug resistance in MM cells ENSG00000162882 PMC6156496__F4 Core interactions between the mTOR pathway and Alzheimer's disease ENSG00000065911 ENSG00000128272 ENSG00000150907 ENSG00000112561 PMC10948527__F2 SHP2 signaling pathways: SHP2-dependent signaling in both developing and established cancer cells is illustrated, with arrows denoting positive regulators and T-bars indicating negative regulators ENSG00000033327 ENSG00000291971 ENSG00000169047 ENSG00000198793 ENSG00000141068 ENSG00000168036 PMC2955882__F4 ENaC and ASL volume regulation ENSG00000001626 PMC5354077__F8 From big data to diagnosis and prognosis: gene expression signatures in liver hepatocellular carcinoma ENSG00000172005 ENSG00000026103 PMC4686384__F5 Chemogenomic Study of Carboplatin in Saccharomyces cerevisiae: Inhibition of the NEDDylation Process Overcomes Cellular Resistance Mediated by HuR and Cullin Proteins ENSG00000166167 ENSG00000090621 ENSG00000127528 ENSG00000072803 ENSG00000113194 ENSG00000185104 ENSG00000070756 ENSG00000119138 ENSG00000174748 ENSG00000168461 ENSG00000144566 ENSG00000185787 ENSG00000119402 ENSG00000160785 ENSG00000111540 ENSG00000124209 ENSG00000109670 PMC5036360__F9 CXCL3-induced signaling pathway in adipocytes ENSG00000163734 PMC3484277__F1 Downstream signaling of the IGF-1R ENSG00000169047 ENSG00000198793 PMC10948527__F4 Immune cell-specific roles of SHP2 ENSG00000182578 ENSG00000253293 ENSG00000291603 ENSG00000198053 ENSG00000134982 ENSG00000140968 ENSG00000198793 ENSG00000150637 ENSG00000111537 ENSG00000181847 ENSG00000138755 ENSG00000272398 ENSG00000184371 ENSG00000113263 PMC3484277__F2 Insulin like growth factor (IGF) and insulin receptor (IR) signaling system ENSG00000197081 ENSG00000198793 ENSG00000140443 PMC8841479__F4 Narrative review for the Hippo-YAP pathway in cancer survival and immunity: the Yin-Yang dynamics ENSG00000150457 ENSG00000131023 PMC8841479__F1 Narrative review for the Hippo-YAP pathway in cancer survival and immunity: the Yin-Yang dynamics ENSG00000186575 ENSG00000109321 ENSG00000131023 PMC2635340__F2 Kinetic Scheme for the 5-HT1AR and 5-HT2AR mediated MAP kinase activation pathway ENSG00000134982 ENSG00000087842 ENSG00000104368 PMC4496485__F2 STAT3 signal transduction pathway ENSG00000105397 ENSG00000291971 ENSG00000168610 PMC5085760__F1 Major protein cascade and miRNAs in insulin signaling pathway ENSG00000116688 PMC11394629__F1 Genetics of BCC ENSG00000164690 ENSG00000128602 PMC11048531__F2 Combination of DSF/Cu and chemotherapeutic drugs sensitizes breast cancer (BC) cells and their stem cells by targeting various cellular and signaling mechanisms ENSG00000272398 ENSG00000026508 ENSG00000184207 ENSG00000049768 ENSG00000168610 PMC11394629__F2 Action of Hedgehog Pathway Inhibitors ENSG00000164690 ENSG00000128602 PMC3718700__F4 Presenilin functions ENSG00000142192 ENSG00000135473 ENSG00000168036 PMC9061914__F6 Exposure of primary osteoblasts to combined magnetic and electric fields induced spatiotemporal endochondral ossification characteristic gene- and protein expression profiles ENSG00000105329 ENSG00000118785 ENSG00000178741 ENSG00000168036 ENSG00000137801 ENSG00000143387 PMC4995089__F4 Immune evasive attributes of SpA PMC3886260__F2 Lck is a central node in the T cell receptor signaling pathway PMC7935273__F8 GABA/Beta-glucan supplements on melatonin and serotonin content extracted from natural resources ENSG00000150907 ENSG00000185591 PMC6488418__F4 Figure 2.CD36 redox signaling in vascular smooth muscle cells, microvascular endothelial cells, and monocytes/macrophages ENSG00000135218 ENSG00000010810 ENSG00000079999 PMC12034699__F6 Expression trends of each molecule associated with the interferon signaling pathway based on gene chip analysis The interferon signaling pathway was significantly activated ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000033800 ENSG00000125347 ENSG00000230034 PMC8707654__F6 Metabolomic Profiling of Blood-Derived Microvesicles in Breast Cancer Patients ENSG00000087253 ENSG00000173599 PMC12042829__F1 Annexin A regulates regulated cell death patterns such as autophagy, ferroptosis, and pyroptosis ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000198793 ENSG00000072274 ENSG00000189403 ENSG00000091106 ENSG00000168610 ENSG00000057663 PMC12164893__F1 Klotho protein-mediated network of signaling pathways ENSG00000118972 ENSG00000105550 ENSG00000163737 PMC11024688__F4 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway of the PI3K-AKT (A, B) and mitogen-activated protein kinase (MAPK) (C, D) signaling pathway was mapped by fold changes ENSG00000103479 ENSG00000002330 ENSG00000102871 ENSG00000130522 ENSG00000138798 ENSG00000186716 ENSG00000169047 ENSG00000127191 ENSG00000081189 PMC6945546__F3 Future treatments for HHT ENSG00000170365 ENSG00000291971 ENSG00000120693 ENSG00000091879 ENSG00000163217 PMC6945546__F1 Mutated genes in HHT encode members of the BMP9/BMP10 signaling pathway ENSG00000204217 ENSG00000163217 PMC4740301__F3 Monocyte genes associated with the ML ratio are enriched for genes in the interferon signalling pathway ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000033800 PMC8832734__F1 Long non-coding RNAs as the critical regulators of epithelial mesenchymal transition in colorectal tumor cells: an overview ENSG00000168036 PMC8832734__F2 Long non-coding RNAs as the critical regulators of epithelial mesenchymal transition in colorectal tumor cells: an overview ENSG00000065978 ENSG00000253352 PMC6341270__F1 Mechanism of Nrf2 activation and Nrf2-mediated antioxidant responses in the lungs ENSG00000178573 ENSG00000100387 ENSG00000079999 PMC4023363__F1 PI3K-AKT-mTOR signaling pathway and therapeutic opportunities ENSG00000177169 ENSG00000002330 ENSG00000106070 ENSG00000198793 ENSG00000112561 PMC5665033__F8 How arecoline affects glycolysis and the signaling pathway of anoikis in HA22T/VGH cells ENSG00000159399 PMC10809359__F7 PPI network of the signalling molecules regulating macrophage activity and HIF-1 signalling pathways ENSG00000161016 ENSG00000087245 ENSG00000182511 ENSG00000169896 ENSG00000105193 ENSG00000113520 ENSG00000118520 ENSG00000204936 ENSG00000136942 ENSG00000112306 PMC7668240__F3 Transcriptomic and Quantitative Proteomic Profiling Reveals Signaling Pathways Critical for Pancreatic Islet Maturation ENSG00000228716 ENSG00000073584 ENSG00000136854 ENSG00000169710 ENSG00000182985 ENSG00000120885 ENSG00000166508 ENSG00000106546 ENSG00000183765 ENSG00000101868 ENSG00000149269 ENSG00000170893 ENSG00000220205 ENSG00000123374 ENSG00000171560 ENSG00000019505 ENSG00000133818 ENSG00000262785 ENSG00000090776 ENSG00000145920 ENSG00000169213 ENSG00000135446 ENSG00000145321 ENSG00000175175 ENSG00000079435 ENSG00000080839 ENSG00000011347 ENSG00000127616 PMC4547013__F1 Network of miRNAs and target genes in OS ENSG00000112242 ENSG00000143476 ENSG00000136997 ENSG00000067900 ENSG00000168610 ENSG00000146648 ENSG00000140443 PMC7667664__F2 Efferocytosis in health and disease ENSG00000153208 ENSG00000135218 ENSG00000168615 ENSG00000132170 PMC5842195__F2 Cell cycle arrest signaling ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC7667664__F3 Efferocytosis in health and disease ENSG00000167601 ENSG00000010017 PMC7667664__F1 Efferocytosis in health and disease ENSG00000153208 ENSG00000181790 ENSG00000118515 PMC4317307__F7 Proposed models of adiponectin metabolic pathway and associated genes ENSG00000150782 ENSG00000157500 ENSG00000159346 ENSG00000113520 ENSG00000285070 PMC8148450__F5 Transcriptomic profile of the mice aging lung is associated with inflammation and apoptosis as important pathways ENSG00000175054 ENSG00000157764 ENSG00000213658 ENSG00000179091 ENSG00000177606 ENSG00000172005 ENSG00000084774 PMC3705163__F8 Schematic model indicating proposed mechanisms by which mutant p53 GOF induces EMT ENSG00000168283 ENSG00000136826 PMC9493169__F4 Bruton tyrosine kinase inhibitors in B-cell lymphoma: beyond the antitumour effect ENSG00000162711 ENSG00000108691 ENSG00000125538 ENSG00000172936 ENSG00000010671 PMC4074399__F1 Cell Death Pathways ENSG00000102871 ENSG00000120868 ENSG00000168040 ENSG00000127191 PMC3713357__F1 Possible pathways for growth factor mediated tumorigenesis ENSG00000198793 PMC5306231__F2 Possible cell-cycle checkpoint pathways in centrosomal (centriolar) integrity or morphology ENSG00000166579 ENSG00000142731 ENSG00000048028 PMC7312607__F7 Enriched pathway maps ENSG00000004478 ENSG00000111537 ENSG00000172216 ENSG00000100906 ENSG00000163914 ENSG00000177606 ENSG00000196591 ENSG00000132478 ENSG00000116030 ENSG00000155974 ENSG00000168610 ENSG00000113448 PMC5390895__F7 Late gestational intermittent hypoxia induces metabolic and epigenetic changes in male adult offspring mice ENSG00000173080 ENSG00000145365 ENSG00000125851 ENSG00000116741 ENSG00000281123 ENSG00000069956 ENSG00000173612 ENSG00000160741 ENSG00000285069 ENSG00000186716 ENSG00000100348 ENSG00000285438 ENSG00000184304 PMC4342024__F9 GPCR-mediated PLC/PKCB/PKD/SSH2 signaling pathway to regulate cofilin activity ENSG00000149782 ENSG00000137841 ENSG00000141298 PMC6721501__F2 Figure depicts pathways that cross-talk with Hh pathway leading to its non-canonical activation ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000128602 ENSG00000146648 PMC2628375__F7 Hypothetical scheme of activation of the murine Hamp1 promoter ENSG00000170365 ENSG00000168610 PMC6721501__F1 Figure depicts canonical hedgehog signaling pathway ENSG00000106571 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC8664074__F1 Novel oncogenes and tumor suppressor genes in hepatocellular carcinoma (HCC) initiation and progression ENSG00000170608 ENSG00000166326 ENSG00000187531 ENSG00000119401 ENSG00000126457 ENSG00000049768 ENSG00000101557 ENSG00000117650 ENSG00000102226 ENSG00000109805 ENSG00000146054 ENSG00000280610 ENSG00000124523 ENSG00000096717 ENSG00000189299 ENSG00000171604 ENSG00000164916 PMC7966997__F4 EGFR pathway (Biocarta) shown as an interacting network for samples with maximal (top) or minimal (bottom) PAL in colorectal cancer (left) vs normal colon (right) ENSG00000167941 ENSG00000138798 ENSG00000166501 ENSG00000065559 ENSG00000121879 ENSG00000168610 ENSG00000146648 PMC7721156__F3 Interaction of preimplantation factor with the global bovine endometrial transcriptome ENSG00000149311 ENSG00000226275 ENSG00000213658 ENSG00000186716 ENSG00000175104 PMC5011655__F6 Systems Pharmacology Dissection of the Integrated Treatment for Cardiovascular and Gastrointestinal Disorders by Traditional Chinese Medicine ENSG00000170890 ENSG00000002330 ENSG00000188257 ENSG00000170214 ENSG00000137672 ENSG00000100985 ENSG00000151617 ENSG00000102468 ENSG00000007171 PMC3276511__F2 Mass Homozygotes Accumulation in the NCI-60 Cancer Cell Lines As Compared to HapMap Trios, and Relation to Fragile Site Location ENSG00000277336 ENSG00000134339 ENSG00000102962 ENSG00000179934 ENSG00000168329 ENSG00000145147 ENSG00000183625 ENSG00000145826 ENSG00000149294 ENSG00000168036 ENSG00000274736 ENSG00000163737 ENSG00000121807 ENSG00000011422 ENSG00000108688 ENSG00000181374 ENSG00000185008 ENSG00000112486 ENSG00000151882 ENSG00000143185 ENSG00000275718 ENSG00000275385 ENSG00000184451 ENSG00000186810 ENSG00000017797 ENSG00000108691 ENSG00000136960 ENSG00000161921 ENSG00000137077 ENSG00000010810 ENSG00000006451 ENSG00000102970 ENSG00000108700 ENSG00000026508 ENSG00000126353 ENSG00000275095 ENSG00000154134 ENSG00000115009 PMC7966997__F1 EGFR pathway (Qiagen Pathway Central) shown as an interacting network for samples with maximal (top) or minimal (bottom) PAL in colorectal cancer (left) vs normal colon (right) ENSG00000198517 ENSG00000175097 ENSG00000146648 ENSG00000082212 PMC7966997__F2 EGFR pathway (Biocarta) shown as an interacting network for samples with maximal (top) or minimal (bottom) PAL in colorectal cancer (left) vs normal colon (right) ENSG00000167941 ENSG00000138798 ENSG00000166501 ENSG00000065559 ENSG00000121879 ENSG00000168610 ENSG00000146648 ENSG00000160691 PMC7721156__F2 Interaction of preimplantation factor with the global bovine endometrial transcriptome ENSG00000197893 ENSG00000198517 ENSG00000168040 ENSG00000168404 ENSG00000164305 PMC9498798__F5 Gene Regulation during Carapacial Ridge Development of Mauremys reevesii: The Development of Carapacial Ridge, Ribs and Scutes ENSG00000095739 ENSG00000164161 ENSG00000134982 ENSG00000167941 ENSG00000113558 ENSG00000121067 ENSG00000171791 ENSG00000128602 PMC6613812__F1 PI3K/Akt pathway plays a central role in nutrient-mediated cell proliferation and growth ENSG00000011566 PMC2653092__F5 Basic Helix-Loop-Helix Factor Hand2 Regulates Autonomic Nervous System Development ENSG00000123454 ENSG00000164107 ENSG00000107485 ENSG00000109132 ENSG00000165462 PMC4754024__F1 Transcriptional regulation of IL-12p40 (IL12b) in antigen-presenting cells ENSG00000157557 ENSG00000239732 ENSG00000140968 ENSG00000172936 ENSG00000136869 PMC7188049__F3 Role of ACE2 (angiotensin-converting enzyme 2) in the pathogenesis of coronavirus disease 2019 and the inflammatory response ENSG00000175054 ENSG00000130234 ENSG00000184012 PMC9127157__F4 Emerging Roles and Therapeutic Implications of Epigenetic Modifications in Ovarian Cancer ENSG00000145824 ENSG00000178860 ENSG00000120868 ENSG00000175104 ENSG00000168610 PMC8964039__F2 Long Non-coding RNAs in the Development of Aging-Related Neurodegenerative Diseases ENSG00000142192 PMC9127157__F5 Emerging Roles and Therapeutic Implications of Epigenetic Modifications in Ovarian Cancer ENSG00000012048 ENSG00000111537 ENSG00000168036 ENSG00000122592 PMC4871813__F2 Schematic illustration of B-cell activating factor (BAFF) signaling pathway ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC8714130__F9 Tartary buckwheat flavonoids relieve the tendency of mammary fibrosis induced by HFD during pregnancy and lactation ENSG00000125538 ENSG00000005381 PMC3899188__F1 Regulation of lysosome biogenesis and functions in osteoclasts ENSG00000225190 ENSG00000112561 ENSG00000081087 ENSG00000111670 ENSG00000011347 ENSG00000057663 ENSG00000110719 ENSG00000143387 PMC7898550__F9 Schematic diagram describing the mechanism in the inhibitory effect of PQS on NR inflammatory injury ENSG00000162711 ENSG00000172936 ENSG00000136869 PMC3121598__F10 The interplay between leptin, IGF-1 and AB42 ENSG00000169047 ENSG00000140443 PMC12108893__F4 In malignant cells, the biosynthesis of fatty acids and cholesterol both use acetyl-CoA as the starting substrate ENSG00000131473 ENSG00000135218 ENSG00000130164 ENSG00000113161 ENSG00000169710 ENSG00000026103 PMC10976710__F4 Molecular connection between the mTOR signaling pathway and polyploid giant cancer cells: (A) The interplay between polyploidy, senescence and mTOR signaling ENSG00000198793 ENSG00000026508 PMC8700172__F1 Role of CCN Proteins in Breast Cancer: Therapeutic Advances and Perspectives ENSG00000104415 ENSG00000136999 ENSG00000122691 ENSG00000138798 ENSG00000170558 ENSG00000168036 ENSG00000140443 ENSG00000064205 PMC6495097__F8 Model of the Action circSNX29 Competitively Sponging miR-744-Mediating Myoblasts Differentiation ENSG00000122180 ENSG00000123374 ENSG00000131196 PMC5768893__F6 Schematic Representation of FGF4 Signaling Regulated by O-GlcNAc in ESCsPhosphorylated PKCζ, the active form, activates the MEK-ERK1/2 pathway by FGF4 stimulation ENSG00000147162 ENSG00000141448 PMC9184702__F6 Effect of D-Met supplementation on the milk protein synthesis pathway ENSG00000124102 ENSG00000198793 ENSG00000156976 PMC10931919__F1 Origins and intracellular sensors of self-nucleic acids promoting the IFN-I signaling pathway ENSG00000183735 ENSG00000213928 ENSG00000239732 ENSG00000164430 ENSG00000105397 ENSG00000164342 ENSG00000142166 PMC8692837__F3 Mechanobiological Implications of Cancer Progression in Space ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000182580 ENSG00000196628 ENSG00000133216 PMC4028364__F1 Conservation of host cells and pathogen categories in zebrafish and mammalian infection by eukaryotes ENSG00000125538 ENSG00000169429 PMC8891017__F7 Genetic associations of protein-coding variants in human disease ENSG00000134982 ENSG00000198734 PMC2927928__F3 Molecular pathways involved in pancreas and liver differentiation from hES cells ENSG00000070193 ENSG00000125398 ENSG00000139515 ENSG00000163623 ENSG00000081051 ENSG00000168267 ENSG00000163631 PMC4813275__F1 Pathways that represent potential targets for miRNAs in drug-resistant GC ENSG00000169047 ENSG00000171791 ENSG00000128602 ENSG00000163501 ENSG00000140443 PMC8145743__F8 CDDO-Me Attenuates Astroglial Autophagy via Nrf2-, ERK1/2-SP1- and Src-CK2-PTEN-PI3K/AKT-Mediated Signaling Pathways in the Hippocampus of Chronic Epilepsy Rats ENSG00000185591 PMC8395072__F3 Transcriptomic Analysis Reveals Key Genes Involved in Oil and Linoleic Acid Biosynthesis during Artemisia sphaerocephala Seed Development ENSG00000173599 ENSG00000198670 ENSG00000173402 PMC3937033__F8 T cell PPI Network mapped to TCR, with main JAK-STAT and MAPK signaling pathways ENSG00000213658 ENSG00000010810 ENSG00000173039 ENSG00000162924 ENSG00000146648 PMC3960190__F1 Perspectives of TGFB inhibition in pancreatic and hepatocellular carcinomas ENSG00000137834 ENSG00000198793 PMC2871322__F1 Schematic of central regulation of body fluid regulation in response to acute changes in sodium and volume ENSG00000167419 PMC12098375__F1 Regulatory mechanism of ERK1/2 signaling in promoting insulin secretion and insulin resistance ENSG00000138798 ENSG00000169047 PMC2871322__F3 Schematic diagram of the forebrain neurocircuitry and peripheral inputs underlying the influences of osmotic and peripheral angiotensin II (Ang II) on sympathetic outflow and the baroreflex ENSG00000167419 PMC4554827__F1 Core of the Hippo pathway ENSG00000109321 ENSG00000089685 ENSG00000114978 ENSG00000150457 ENSG00000114019 ENSG00000131023 PMC6963216__F2 Cascade of events that leads to interferons (IFN) mediated antiviral response ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000125347 ENSG00000142166 PMC6456803__F1 Vitamin D pathway ENSG00000118972 ENSG00000152266 ENSG00000172893 ENSG00000105516 ENSG00000019186 ENSG00000107611 ENSG00000135929 PMC11790448__F1 Adropin regulates multiple signaling pathways ENSG00000096717 ENSG00000168610 PMC4554827__F3 Function of nuclear and cytoplasmic Yes-associated protein (YAP) and transcriptional coactivator with a PDZ-binding domain (TAZ) ENSG00000134371 ENSG00000168036 PMC4470732__F1 Scheme illustrating the ASARM-model and the FAM20C kinase link to the FAP pathway: The numbers highlighted in the circles refer to the explanations in the following text ENSG00000118972 ENSG00000140564 ENSG00000288499 ENSG00000115339 ENSG00000152592 PMC4554827__F4 Signal crosstalk with Yes-associated protein (YAP) and transcriptional coactivator with a PDZ-binding domain (TAZ) ENSG00000109321 ENSG00000130702 ENSG00000138798 ENSG00000168036 ENSG00000150457 ENSG00000131023 ENSG00000089225 PMC8804851__F8 Shockwave Treatment Enhanced Extracellular Matrix Production in Articular Chondrocytes Through Activation of the ROS/MAPK/Nrf2 Signaling Pathway ENSG00000139219 ENSG00000181019 ENSG00000157766 PMC2898451__F8 Schematic illustration of signaling pathways involved in PDGF-mediated induction of Arc expression ENSG00000198576 PMC3426114__F9 Two Possible Models Regarding the Role of CDT1 Proteins in Response to DNA Stress.(A) Downregulation of CDT1 upon DNA stress may be promoted by WEE1 and/or SOG1 ENSG00000149311 ENSG00000175054 ENSG00000167513 PMC7105474__F3 Life, death, and autophagy in cancer: NFKB turns up everywhere ENSG00000104856 ENSG00000173039 ENSG00000127191 PMC3813433__F1 Dietary flavonoid fisetin: A novel dual inhibitor of PI3K/Akt and mTOR for prostate cancer management ENSG00000198793 ENSG00000164327 ENSG00000166278 PMC3475760__F1 As a key downstream target of PI3K-mediated signaling pathway in response to extracellular stimuli such as growth factors through receptor tyrosine kinase (RTK), Akt plays an important role in regulation of diverse cellular processes PMC12121814__F10 Multifaceted roles of the small EV proteome in NP cell and tissue homeostasis PMC8199608__F1 Serotonin Receptors in Neurodevelopmental Disorders: Focus on 5-HT7 Receptor ENSG00000070831 ENSG00000026508 PMC10759449__F8 Protein disulfide isomerase family member 4 promotes triple-negative breast cancer tumorigenesis and radiotherapy resistance through JNK pathway ENSG00000155660 PMC7913382__F5 Mitogen-activated protein kinase (MAPK)/ extracellular signal-regulated kinase (ERK) pathway crosstalk, downstream effects, and inhibitors currently being trialled in pancreatic cancer treatment ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC7913382__F6 PI3K/AKT/mTOR pathway in pancreatic cancer is central for cancer cell growth, survival, migration, invasion, angiogenesis, and modulation of the anti-cancer immune response ENSG00000101255 ENSG00000168610 PMC10932453__F2 Non-coding RNAs in the host response to M ENSG00000171150 ENSG00000177606 ENSG00000138032 ENSG00000095015 PMC10932453__F3 Immune response of the tracheal mucosa to M ENSG00000138378 ENSG00000111537 ENSG00000134982 ENSG00000181374 ENSG00000136869 PMC8508814__F1 Inhibition of APE1/Ref-1 for Neovascular Eye Diseases: From Biology to Therapy ENSG00000168610 PMC7690676__F2 Competing endogenous RNA (ceRNA) mechanisms and potential downstream regulatory mechanisms of NNT-AS1 ENSG00000154485 ENSG00000168036 ENSG00000105810 PMC3847144__F1 Isoprenoid and amino acid biosynthetic pathways ENSG00000110921 ENSG00000197429 PMC3161420__F1 Regulation of apoptosis by the BCL-2 family ENSG00000002330 ENSG00000104081 ENSG00000026103 PMC3355940__F2 K63-linked polyubiquitination in the activation of canonical and non-canonical NFKB signaling pathway ENSG00000083799 ENSG00000127191 ENSG00000184216 PMC4683180__F2 Tentative metabolic pathway model of membrane-bound electron transport in Methanoperedens ENSG00000182511 ENSG00000116984 PMC3340361__F1 RAB-7 Antagonizes LET-23 EGFR Signaling during Vulva Development in Caenorhabditis elegans ENSG00000110395 ENSG00000138798 ENSG00000146648 PMC4716037__F1 Deregulation of Hippo pathway in gastric cancer ENSG00000144560 ENSG00000197905 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC4832581__F2 Cellular iron homeostasis and putative involvement of NBIA‐associated genes ENSG00000184381 ENSG00000292221 ENSG00000103089 ENSG00000131943 ENSG00000068120 ENSG00000115827 PMC9019922__F5 DSPP signalling during dentineogenesis and dentine regeneration ENSG00000170365 ENSG00000168487 ENSG00000152591 PMC7184741__F6 Glyoxylic acid overcomes 1-MCP-induced blockage of fruit ripening in Pyrus communis L. var. ‘D’Anjou’ ENSG00000026103 ENSG00000116984 PMC4806539__F2 Biological networks according to IPA of 1370 genes related to HNSCC ENSG00000012048 ENSG00000100906 ENSG00000109320 PMC6176484__F4 Therapeutic targeting of oncogenic transcription factors by natural products in eye cancer ENSG00000281324 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC6326357__F1 Role of MAIT cells in spondyloarthritis (SpA) ENSG00000162594 ENSG00000134982 ENSG00000153029 ENSG00000121807 ENSG00000112486 ENSG00000168685 PMC6176484__F2 Therapeutic targeting of oncogenic transcription factors by natural products in eye cancer ENSG00000135446 ENSG00000105810 ENSG00000198625 PMC11809324__F7 Treg cell aging and regulatory role of PD‐1 in advanced‐age pregnancies ENSG00000120875 PMC9326111__F6 Capsaicin: A Two-Decade Systematic Review of Global Research Output and Recent Advances Against Human Cancer ENSG00000002330 ENSG00000156026 ENSG00000165125 ENSG00000196689 PMC5722594__F1 Soluble PD-1 and PD-L1: predictive and prognostic significance in cancer ENSG00000291603 ENSG00000186716 PMC5366313__F5 Representative view of the iNKT/innate CD8(+) T-cell axis hypothesis in chronic myeloid leukemia (CML) ENSG00000150782 ENSG00000158473 ENSG00000163914 PMC7286881__F10 Exploring the mechanism of Shengmai Yin for coronary heart disease based on systematic pharmacology and chemoinformatics ENSG00000274619 ENSG00000157404 ENSG00000143839 ENSG00000155657 PMC10672974__F13 Recent Advances in Drug Discovery for Triple-Negative Breast Cancer Treatment ENSG00000169047 ENSG00000198793 PMC7286881__F14 Exploring the mechanism of Shengmai Yin for coronary heart disease based on systematic pharmacology and chemoinformatics ENSG00000175206 ENSG00000003436 ENSG00000171105 ENSG00000110799 ENSG00000173039 ENSG00000171791 ENSG00000115718 ENSG00000163737 ENSG00000073756 ENSG00000178726 ENSG00000007171 ENSG00000104368 ENSG00000137801 ENSG00000126218 ENSG00000150782 ENSG00000226275 ENSG00000108691 ENSG00000138823 ENSG00000102245 ENSG00000128052 ENSG00000015520 ENSG00000100979 ENSG00000136869 ENSG00000156113 PMC6603234__F3 Outline of potential mechanism of sEH inhibition-stabilized EETs in inhibiting colonic adenoma—carcinoma sequence via targeting inflammation and its activated Wnt/mutant p53 signals ENSG00000134982 PMC5057284__F3 Circadian oscillations in intracellular organelle’s structure and function ENSG00000149311 ENSG00000177169 ENSG00000105835 ENSG00000128272 ENSG00000132326 ENSG00000179094 ENSG00000100219 ENSG00000136936 ENSG00000214253 PMC8186902__F4 HIF-1 signaling pathway with overlay data from differential expression and reporter metabolites analysis ENSG00000111537 ENSG00000198517 ENSG00000136869 PMC7765462__F10 Scenarios of SK3-Orai1 interplay ENSG00000167323 ENSG00000293604 ENSG00000147955 PMC5650067__F9 Interacting post-muscarinic receptor signaling pathways potentiate matrix metalloproteinase-1 expression and invasion of human colon cancer cells ENSG00000291971 ENSG00000146648 PMC4805359__F4 Schematic representation of the proposed model to explain NHR-49/PPARA function in promoting the longevity of germline-less animals (modified from Ratnappan et al.,) ENSG00000129347 ENSG00000113649 PMC8350166__F1 PD-1/PD-L1 Axis as a Potential Therapeutic Target for Multiple Sclerosis: A T Cell Perspective ENSG00000134982 ENSG00000198793 ENSG00000168610 PMC6902900__F2 Overview of cellular metabolism in T cells ENSG00000157184 ENSG00000163599 ENSG00000150907 ENSG00000136997 ENSG00000155792 ENSG00000049768 ENSG00000026103 PMC8616823__F2 Cell communication involved in tumour establishment, invasion and immune escape ENSG00000108691 ENSG00000239732 ENSG00000133048 ENSG00000203710 ENSG00000106546 PMC7369235__F8 Signaling mechanisms of BCR-induced CSR ENSG00000104856 ENSG00000186716 ENSG00000197943 ENSG00000131323 ENSG00000127191 ENSG00000010671 PMC10907606__F8 Hypothetical model showing the role of OAT in IPF pathogenesis ENSG00000100033 PMC4887650__F1 TLR4 intracellular signaling pathways ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000175104 PMC4182113__F1 Interferons: Success in anti-viral immunotherapy ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC7157451__F2 IFNA and IFNB bind to the type I IFN receptor (IFNAR) and activate the expression of numerous ISGs via the JAK/STAT pathway ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000185745 ENSG00000160710 ENSG00000276561 ENSG00000172183 PMC3841209__F9 Off-label use of cetuximab plus sorafenib and panitumumab plus regorafenib to personalize therapy for a patient with V600E BRAF-mutant metastatic colon cancer ENSG00000157764 ENSG00000146648 PMC6263145__F2 Mitochondrial Quality Control in the Diabetic Heart ENSG00000177169 ENSG00000123395 ENSG00000198793 ENSG00000145782 PMC6679985__F3 Circadian Clocks and Cancer: Time-Keeping Governs Cellular Metabolism ENSG00000136997 ENSG00000108788 PMC4849272__F3 Hepcidin antagonists ENSG00000010704 ENSG00000106327 ENSG00000178752 ENSG00000168610 PMC12174671__F3 Simplified visualization of NAD+ production pathways ENSG00000105835 ENSG00000278488 ENSG00000157064 ENSG00000173614 PMC3710659__F9 The proposed signaling pathways for 8-iso-PGF2Alpha-mediated modulation of human platelet function ENSG00000047410 ENSG00000163914 PMC5511860__F6 BMP-2 induced EMT and breast cancer stemness through Rb and CD44 signaling ENSG00000170365 ENSG00000026508 PMC5479927__F1 CoQ biosynthesis and effect of 4-HB analogs ENSG00000132423 ENSG00000119723 ENSG00000110871 ENSG00000197429 ENSG00000173085 ENSG00000167186 PMC3945521__F7 TRIMmunity: The roles of the TRIM E3-ubiquitin ligase family in innate antiviral immunity ENSG00000183735 ENSG00000140968 ENSG00000157625 ENSG00000131323 ENSG00000130159 ENSG00000164342 PMC3022513__F1 Physiological regulation of the mTOR signaling pathway ENSG00000198793 ENSG00000168036 PMC8324684__F3 Metabolic-associated fatty liver disease and lipoprotein metabolism ENSG00000213996 ENSG00000042832 ENSG00000138823 PMC10886332__F3 Co-expression network for the PP group based on lncRNA key regulators ENSG00000151014 ENSG00000105664 PMC7906148__F4 Analysis of 219 hub genes with degree ≥10 ENSG00000125266 ENSG00000125740 ENSG00000154764 ENSG00000041982 ENSG00000128917 ENSG00000169047 ENSG00000158517 ENSG00000116701 ENSG00000001626 ENSG00000169242 ENSG00000073756 ENSG00000143387 PMC8869528__F1 Insights into the Role of Gremlin-1, a Bone Morphogenic Protein Antagonist, in Cancer Initiation and Progression ENSG00000170365 ENSG00000137834 PMC10467107__F7 Cardiac Toxicity Induced by Long-Term Environmental Levels of MC-LR Exposure in Mice ENSG00000198793 PMC9646898__F4 Identification of a TNF-TNFR-like system in malaria vectors (Anopheles stephensi) likely to influence Plasmodium resistance ENSG00000102871 ENSG00000177606 ENSG00000056558 ENSG00000131323 ENSG00000168040 ENSG00000127191 ENSG00000076604 PMC8145841__F2 Enigmatic Evolutionary History of Porphobilinogen Deaminase in Eukaryotic Phototrophs ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000188690 PMC2757699__F1 Metabolic fate of the 13C-label from [1-13C]-glucose ENSG00000159399 ENSG00000026103 PMC5288170__F1 Molecular mechanisms of OLIG2 transcription factor in brain cancer ENSG00000071564 ENSG00000066468 ENSG00000184221 ENSG00000117425 ENSG00000135446 ENSG00000205927 ENSG00000105810 ENSG00000164690 ENSG00000128602 PMC5067332__F1 Inositol mechanisms of action in cancer cells ENSG00000138798 ENSG00000067900 PMC5676473__F1 Schematic diagram of Nrf2 signaling and regulation in the corneal epithelial cells ENSG00000181019 ENSG00000086991 ENSG00000079999 PMC3831179__F15 Pathway Commons (accessed through Cytoscape) ENSG00000170365 ENSG00000137834 ENSG00000157933 PMC3012148__F2 Biosynthetic pathway of sphingolipids that mediate expressions of genes associated with cellular processes in cancer ENSG00000100422 ENSG00000213015 ENSG00000167323 ENSG00000243709 ENSG00000135446 ENSG00000131095 ENSG00000265972 ENSG00000146648 ENSG00000062485 PMC6798356__F2 COPD creates a favourable microenvironment for lung cancer initiation and progression ENSG00000196154 PMC3562183__F2 Expression Microarray Meta-Analysis Identifies Genes Associated with Ras/MAPK and Related Pathways in Progression of Muscle-Invasive Bladder Transition Cell Carcinoma ENSG00000145604 ENSG00000117020 ENSG00000157764 ENSG00000010810 ENSG00000134215 ENSG00000123374 ENSG00000196712 ENSG00000026103 ENSG00000150630 PMC4055784__F2 The interactome space of the edible plants associated to colon cancer ENSG00000087085 ENSG00000154016 ENSG00000132341 PMC5528323__F6 Pathways of steroid hormone synthesis, metabolism and tissue sensitivity to HRT (Kelemen et al., 2008; Pasqualini and Chetrite, 2005; Masson et al., 2010) MiRNA's predicted to target steroidogenic or metabolizing enzymes are encased in blue ENSG00000108786 ENSG00000082175 ENSG00000140505 ENSG00000116791 ENSG00000137573 ENSG00000146648 ENSG00000117399 ENSG00000175305 PMC4774640__F3 Schematic representation of the ectoenzymes and transporters involved in the extracellular ATP metabolism ENSG00000197594 ENSG00000001626 PMC11347096__F5 Schematic diagram summarizes the regulation of lipid metabolism in normal or malignant B cells ENSG00000063176 ENSG00000291971 ENSG00000186716 ENSG00000136997 ENSG00000169710 ENSG00000172936 ENSG00000148154 ENSG00000010671 ENSG00000198286 PMC3035871__F2 Targeting Fas in osteoresorptive disorders ENSG00000196411 ENSG00000170365 ENSG00000128272 ENSG00000162337 ENSG00000177606 ENSG00000131196 PMC11347096__F6 Schematic diagram summarizes the potential therapeutic targets of different lipid species and related pathways to treat inflammatory disease or B cell malignancy ENSG00000063176 ENSG00000186716 ENSG00000198793 ENSG00000136997 ENSG00000196591 ENSG00000148154 ENSG00000010671 ENSG00000026103 PMC11347096__F3 Cholesterol metabolism is necessary to defend against foreign antigens ENSG00000177455 ENSG00000291971 ENSG00000186716 ENSG00000198793 ENSG00000113161 ENSG00000172936 ENSG00000142089 ENSG00000160179 ENSG00000010671 PMC11347096__F4 Sphingolipid metabolism ENSG00000100422 ENSG00000102172 PMC11347096__F2 Phospholipids and their binding proteins mediate normal or malignant B cell activation ENSG00000177455 ENSG00000291971 ENSG00000186716 ENSG00000010671 ENSG00000198286 PMC4859980__F1 HSV modulates apoptosis signaling ENSG00000132906 ENSG00000213658 ENSG00000102871 ENSG00000168040 ENSG00000064012 ENSG00000164305 PMC2909319__F9 Model: a Src-Tks5-Nck signalling pathway in invadopodia ENSG00000124102 ENSG00000291971 PMC3104012__F1 Summary of the common pathways underlying neurodegenerative diseases and cancer that are mediated by miRNAs ENSG00000149311 ENSG00000107859 ENSG00000142192 ENSG00000088305 ENSG00000136997 ENSG00000174744 ENSG00000067798 ENSG00000105810 ENSG00000258643 ENSG00000164305 PMC6025008__F4 ER stress and the UPR in insulin resistance and diabetes ENSG00000128272 ENSG00000144895 ENSG00000121351 ENSG00000100219 PMC5380946__F1 TRIM38-mediated negative regulation of TLR3/4-mediated and TNF/IL-1-triggered signaling ENSG00000183735 ENSG00000183496 ENSG00000112343 ENSG00000125538 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC5940409__F7 Metabolic changes associated with metformin potentiates Bcl-2 inhibitor, Venetoclax, and CDK9 inhibitor, BAY1143572 and reduces viability of lymphoma cells ENSG00000149311 ENSG00000168610 PMC3831179__F14 Pathway databases ENSG00000138798 ENSG00000177606 ENSG00000168610 PMC5380946__F2 Sumoylation promotes the stability of cGas and Sting and regulates the kinetics of the response to a DNA virus ENSG00000163904 ENSG00000112343 PMC1573858__F1 AT1 receptor signal transduction pathways that result in transcriptional NA neuromodulation (a) and increased firing rate (b) in neuronal cultures ENSG00000123454 ENSG00000177606 ENSG00000111816 PMC10178434__F2 D+ synthesis pathways ENSG00000105835 ENSG00000278488 ENSG00000157064 ENSG00000173614 PMC10607347__F3 The anti-apoptotic action of MSCs in the hepatocyte–MSC co-cultures ENSG00000178860 ENSG00000019991 ENSG00000198793 ENSG00000137193 ENSG00000159399 PMC4961213__F3 IFN-induced Guanylate Binding Proteins in Inflammasome Activation and Host Defense ENSG00000154451 ENSG00000278718 ENSG00000150782 ENSG00000213928 ENSG00000117226 ENSG00000115415 ENSG00000163568 ENSG00000112186 ENSG00000125347 PMC8101356__F6 Core transcriptional networks in Williams syndrome: IGF1-PI3K-AKT-mTOR, MAPK and actin signaling at the synapse echo autism ENSG00000175206 ENSG00000140678 ENSG00000070831 ENSG00000153094 ENSG00000144744 ENSG00000173039 ENSG00000163295 ENSG00000117322 ENSG00000196628 ENSG00000226275 ENSG00000088888 ENSG00000133961 ENSG00000114166 ENSG00000086730 PMC4407539__F8 Predicted model of the immune response of Epinephelus coioides larvae to V ENSG00000039537 ENSG00000291559 ENSG00000166278 ENSG00000182326 ENSG00000236625 PMC8101356__F5 Core transcriptional networks in Williams syndrome: IGF1-PI3K-AKT-mTOR, MAPK and actin signaling at the synapse echo autism ENSG00000196411 ENSG00000172830 ENSG00000070831 ENSG00000081237 ENSG00000183625 ENSG00000163914 ENSG00000172005 ENSG00000015285 ENSG00000113758 ENSG00000084112 ENSG00000141298 ENSG00000145819 PMC3982149__F6 Antibody against CD44s Inhibits Pancreatic Tumor Initiation and Post-Radiation Recurrence in Mice ENSG00000275126 ENSG00000168610 PMC7048745__F2 Ubiquitination in tumor metabolism regulation ENSG00000079387 ENSG00000114388 ENSG00000127452 ENSG00000182670 ENSG00000169047 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000169914 ENSG00000167965 ENSG00000099910 ENSG00000123124 ENSG00000134086 ENSG00000103657 ENSG00000176641 ENSG00000109670 ENSG00000264522 ENSG00000055483 ENSG00000033800 ENSG00000127191 ENSG00000145604 ENSG00000145979 ENSG00000135913 ENSG00000138468 ENSG00000083799 ENSG00000175104 ENSG00000122779 ENSG00000130726 PMC7048745__F3 Ubiquitination in immunological tumor microenvironment (TME) modulation ENSG00000112343 ENSG00000113595 ENSG00000119401 ENSG00000159461 ENSG00000169871 ENSG00000276561 ENSG00000110042 ENSG00000101695 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000197530 ENSG00000078747 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000121060 ENSG00000143258 ENSG00000101752 ENSG00000164342 PMC9106713__F1 Cuproptosis: lipoylated TCA cycle proteins-mediated novel cell death pathway ENSG00000136868 ENSG00000182511 ENSG00000123191 ENSG00000137714 PMC9468207__F6 Meta-analysis highlights the key drought responsive genes in genes: PEPC and TaSAG7 are hubs response networks ENSG00000090402 ENSG00000143839 PMC8999052__F6 Wide-Proteome Analysis to Identify Molecular Pathways Involved in Kidney Response to High-Fat Diet in Mice ENSG00000168028 ENSG00000291958 ENSG00000170027 ENSG00000180879 ENSG00000100504 ENSG00000169032 PMC7032688__F5 Wolbachia limits pathogen infections through induction of host innate immune responses ENSG00000168040 ENSG00000127191 PMC10674663__F7 Comparative Analysis of Cd Uptake and Tolerance in Two Mangrove Species (Avicennia marina and Rhizophora stylosa) with Distinct Apoplast Barriers PMC7739442__F1 Inborn errors of immunity conferring predisposition to childhood HSE ENSG00000183735 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000138231 ENSG00000131323 ENSG00000164342 PMC11742494__F7 CHI3L1’s role in the pathology of Alzheimer’s disease through modulation of neuroinflammation ENSG00000133048 ENSG00000168610 PMC7158159__F6 Detailed signaling pathway of G-protein coupled receptor ENSG00000291971 ENSG00000010810 ENSG00000125388 ENSG00000168610 PMC7046483__F3 RANK/RANKL/OPG pathway in fatty acids‐modulated bone metabolism ENSG00000291971 ENSG00000177606 ENSG00000175104 PMC7483535__F7 Long-term Changes in the Central Amygdala Proteome in Rats with a History of Chronic Cocaine Self-administration ENSG00000172680 ENSG00000002330 ENSG00000291971 ENSG00000131196 PMC4369651__F1 Methotrexate pathway ENSG00000228716 ENSG00000173638 ENSG00000136877 ENSG00000137563 PMC7483535__F8 Long-term Changes in the Central Amygdala Proteome in Rats with a History of Chronic Cocaine Self-administration ENSG00000130643 ENSG00000169676 ENSG00000149295 PMC3260552__F4 Melanoma signaling networks, progression, and influences by the BCL-2 family ENSG00000002330 ENSG00000104081 PMC4143829__F1 Model expressing the distinct molecular pathways of ER transcription factors regulatory actions ENSG00000291971 ENSG00000146648 PMC7607069__F9 TP53 signaling pathway via cBioPortal ENSG00000198625 PMC11742494__F2 CHI3L1-induced tumor angiogenesis, growth, migration, invasion, and inflammation ENSG00000123496 ENSG00000133048 ENSG00000026508 ENSG00000169429 ENSG00000100985 PMC6789471__F4 Protein–protein interaction (PPI) network of the set of DEGs/DEPs identified in the overrepresented GO Immune System Process terms ENSG00000063978 ENSG00000157764 ENSG00000204103 ENSG00000103035 ENSG00000105401 ENSG00000171475 ENSG00000285152 ENSG00000105647 ENSG00000042753 ENSG00000138071 ENSG00000168040 ENSG00000164488 ENSG00000103490 ENSG00000167535 ENSG00000177606 ENSG00000136997 ENSG00000159352 ENSG00000183864 ENSG00000121060 ENSG00000100365 PMC7769847__F2 Schematic summary of Osx’s mission in the complex communications among different bone cells and its potential role in bone micro-environment ENSG00000110711 ENSG00000167941 ENSG00000152592 ENSG00000100985 ENSG00000108821 ENSG00000131196 PMC4358097__F11 Plasma treatment abolish siRNA-induced knockdown of NRF2 ENSG00000181019 ENSG00000130522 ENSG00000177606 ENSG00000164400 ENSG00000156273 ENSG00000079999 PMC7769847__F3 Overview of crosstalk pathways associated with Osx ENSG00000281324 ENSG00000162337 ENSG00000120149 ENSG00000167941 ENSG00000197594 ENSG00000109906 ENSG00000108821 PMC3675380__F2 Synergy between TCR/CD28 and TNFR signalosomes for activation of the PI3K-Akt pathway in T cells ENSG00000134982 PMC9027994__F1 Proline Metabolism in Malignant Gliomas: A Systematic Literature Review ENSG00000100033 PMC8697421__F3 Type I IFN immunity in viral pneumonia ENSG00000183735 ENSG00000213928 ENSG00000115415 ENSG00000131323 ENSG00000110057 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC8697421__F1 Inborn errors of immunity underlying severe cutaneous HPV infections ENSG00000291603 ENSG00000101109 ENSG00000213658 ENSG00000102158 ENSG00000159753 ENSG00000269335 ENSG00000015285 ENSG00000113263 ENSG00000171608 ENSG00000121966 ENSG00000198286 PMC3509894__F3 Vitamin B12 Synthesis and Salvage Pathways Were Acquired by Horizontal Gene Transfer to the Thermotogales ENSG00000142192 ENSG00000110395 PMC3675380__F1 Tumor necrosis factor receptor family molecules that possibly activate the PI3K-Akt pathway in T cells ENSG00000139193 ENSG00000226275 ENSG00000082512 ENSG00000056558 ENSG00000131323 ENSG00000127191 PMC10834974__F5 Novel preliminary metabolomic panel for IHD diagnostics and pathogenesis ENSG00000039537 ENSG00000166278 PMC6980368__F2 S1P signaling in HCC progression ENSG00000019991 ENSG00000137673 ENSG00000170989 ENSG00000127191 ENSG00000183018 PMC9340492__F1 Zebrafish models of inflammation in hematopoietic development and disease ENSG00000151702 ENSG00000183735 ENSG00000213928 ENSG00000111537 ENSG00000159216 ENSG00000125538 ENSG00000179348 PMC7996784__F2 Mevalonate and methylerythritol 4-phosphate pathways in Cannabis sativa ENSG00000197429 ENSG00000167508 ENSG00000082212 PMC9359975__F6 Extracellular vesicles derived from Wharton’s Jelly mesenchymal stem cells inhibit the tumor environment via the miR-125b/HIF1A signaling pathway ENSG00000169554 ENSG00000122691 PMC8827057__F8 Overview diagram describing the mechanism of the inhibitory effect of HF-MSCs on HSCs PMC6945783__F1 Scheme of the functional patterns within the glycolytic pathway in beta cells in health and type 1 diabetes PMC6791856__F8 Endothelial cell pyroptosis plays an important role in Kawasaki disease via HMGB1/RAGE/cathespin B signaling pathway and NLRP3 inflammasome activation ENSG00000162711 ENSG00000189403 PMC5552660__F1 Cholinergic anti-inflammatory pathway (CAP) PMC8636596__F3 Alternatively Spliced Isoforms of Key Molecules in the cGAS-STING Signaling Pathway ENSG00000183735 ENSG00000088888 PMC8469138__F4A Molecular Biology Networks and Key Gene Regulators for Inflammatory Biomarkers Shared by Breast Cancer Development: Multi-Omics Systems Analysis ENSG00000100385 ENSG00000136997 ENSG00000100979 ENSG00000123838 ENSG00000080618 ENSG00000155657 ENSG00000157131 PMC6411824__F1 Overview of the Nrf2 pathway activation ENSG00000178573 ENSG00000169750 ENSG00000100387 ENSG00000079999 PMC8827057__F1 Experimental design ENSG00000081051 ENSG00000163631 PMC5414761__F8 Proposed mechanism for GDNF-induced proliferation of mesenchymal and epithelial cells in the UGS PMC2886808__F1 Signalling through growth factor receptors can activate the PI3K/Akt/mTOR pathway and the JAK3/STAT5 pathway ENSG00000198793 ENSG00000049768 ENSG00000105639 PMC9949995__F2 Transgenerational epigenetic inheritance of axonal regeneration after spinal cord injury ENSG00000228716 ENSG00000110195 PMC6904864__F1 Small molecules guiding mesenchymal stem cell osteogenic cell fate determination ENSG00000170365 ENSG00000168036 PMC5941175__F4 Kinetic reaction schemes of GroEL–GroES interaction revealed by HS-AFM imaging under different substrate conditions ENSG00000090402 ENSG00000280548 PMC9009033__F3 ARID1A variations in colorectal cancer: a collaborative review ENSG00000117713 ENSG00000134982 ENSG00000198793 ENSG00000087586 ENSG00000049618 ENSG00000166851 ENSG00000121879 ENSG00000189079 ENSG00000109670 PMC4546755__F1 Known regulatory mechanisms of NRF2, highlighting miRNA-mediated influences ENSG00000181019 ENSG00000124762 ENSG00000106546 ENSG00000079999 PMC4546755__F2 Overview of ROS-mediated NRF2 activities ENSG00000181019 ENSG00000079999 PMC4546755__F3 Overview of carcinogenesis and NRF2 responses ENSG00000079999 PMC8020867__F1 Map of net odds () for reactions of glycolysis and the tricarboxylic acid (TCA) cycle ENSG00000197713 ENSG00000047932 PMC7443379__F8 Molecular and cellular basis of left–right asymmetry in vertebrates ENSG00000160973 ENSG00000143768 ENSG00000243709 ENSG00000156574 ENSG00000175550 ENSG00000164093 ENSG00000130283 PMC8371750__F7 Dysregulation of Cells Cycle and Apoptosis in Human Induced Pluripotent Stem Cells Chondrocytes Through p53 Pathway by HT-2 Toxin: An in vitro Study ENSG00000132906 ENSG00000105810 ENSG00000164305 ENSG00000026103 PMC8997421__F1 MicroRNAs and Progesterone Receptor Signaling in Endometriosis Pathophysiology ENSG00000092847 ENSG00000113360 ENSG00000134698 ENSG00000123908 PMC2996483__F3 Oncogenic Notch1 Signalling ENSG00000198793 ENSG00000168685 PMC6720712__F7 Diagram illustrating the underlying mechanism by which that miR-15a regulates the differentiation of chicken intramuscular preadipocytes by targeting ACOX1, SCP2 and ACAA1 in the PPAR signaling pathway ENSG00000161533 PMC7556779__F5 Evasion of the Pattern Recognition Receptor-Type I Interferon (PRR-IFN-I) Pathways by Coronaviruses (CoVs).A simplified schematic of the canonical IFN response after sensing RNA viruses ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000276561 ENSG00000142166 PMC9681554__F9 Melatonin Suppresses Macrophage M1 Polarization and ROS-Mediated Pyroptosis via Activating ApoE/LDLR Pathway in Influenza A-Induced Acute Lung Injury ENSG00000278718 ENSG00000162711 ENSG00000118520 PMC7617722__F3 Fatty acid metabolism and its regulation by E5, E6 and E7 encoded by HPV oncoproteins ENSG00000131473 ENSG00000169710 ENSG00000146648 ENSG00000026103 PMC3711381__F1 ERK pathway, its upstream activators and downstream targets ENSG00000138798 ENSG00000146648 PMC3711381__F3 Htt affects ERK signaling in multiple ways ENSG00000138798 ENSG00000197386 PMC8891382__F2 Tumor Immune Microenvironment and Immunotherapy in Brain Metastasis From Non-Small Cell Lung Cancer ENSG00000019991 ENSG00000087245 ENSG00000137077 ENSG00000138798 ENSG00000125538 ENSG00000198793 ENSG00000100985 PMC9370344__F10 Waterlogging Stress Induces Antioxidant Defense Responses, Aerenchyma Formation and Alters Metabolisms of Banana Plants ENSG00000105722 PMC6044347__F2 The steroidogenic pathway ENSG00000130164 PMC9077970__F4 Dual role of autophagy in acute myeloid leukemia ENSG00000198793 ENSG00000112561 ENSG00000169710 PMC11357512__F2 Signalling pathway in a cardiomyocyte with lamin A/C variant factors such as pERK1/2, pSmad1/2, and TEAD1 affect the gene expression of LMNA mutant cells ENSG00000198626 ENSG00000145349 PMC9077970__F1 Dual role of autophagy in acute myeloid leukemia ENSG00000156171 ENSG00000057663 PMC9077970__F2 Dual role of autophagy in acute myeloid leukemia ENSG00000122025 ENSG00000177169 ENSG00000128272 ENSG00000136997 ENSG00000112561 ENSG00000096717 ENSG00000168610 ENSG00000140464 ENSG00000057663 ENSG00000123124 PMC2849704__F1 Homocysteine metabolism in liver and kidney PMC6548405__F7 CBX2 is required to stabilize the testis pathway by repressing Wnt signaling ENSG00000173894 ENSG00000138795 ENSG00000125398 PMC7042394__F1 Core components of the Hippo pathway in Drosophila and mammalian ENSG00000131023 ENSG00000291442 PMC4987730__F7 Antibody-mediated blockade of the PS signaling pathway in the tumor microenvironment ENSG00000092445 ENSG00000291918 PMC4460803__F2 Recently identified drivers in signaling pathways involved in adrenal tumorigenesis ENSG00000281324 ENSG00000140691 ENSG00000183579 PMC5538796__F1 Endothelial cell metabolism in health and disease: impact of hypoxia ENSG00000117707 ENSG00000026103 PMC11005695__S1 Thermosensitive Bi‐Adjuvant Hydrogel Triggers Epitope Spreading to Promote the Anti‐Tumor Efficacy of Frameshift Neoantigens ENSG00000183735 ENSG00000164430 ENSG00000188158 ENSG00000175104 ENSG00000276561 PMC5791813__F1 Interplay between Nrf2 and Brf2 pathways ENSG00000079999 PMC3773983__F2 Four major signaling pathways in the postsynaptic region of a neuron that combine to form a local signaling network PMC10804064__F2 Comprehensive Review of the Key Characteristics of the Genus Mentha, Natural Compounds and Biotechnological Approaches for the Production of Secondary Metabolites ENSG00000110921 ENSG00000197429 PMC7573470__F1 Life cycle of SARS-CoV-2 and its possible inhibitors ENSG00000130234 ENSG00000184012 PMC7168252__F1 Beclin 1 function in autophagy and the role of its post-translational modifications implicated in cancer ENSG00000177169 ENSG00000123395 ENSG00000198382 ENSG00000126775 ENSG00000186716 ENSG00000146648 PMC2649086__F7 KLF14-mediated TGFBRII silencing ENSG00000266265 ENSG00000185591 ENSG00000169375 PMC4803136__F1 The biologically relevant candidate genes selected in this pharmacogenomic study ENSG00000284320 ENSG00000228716 ENSG00000100714 ENSG00000173638 ENSG00000136877 ENSG00000137563 PMC11202552__F2 Simplified diagram of the insulin signaling pathway ENSG00000150907 ENSG00000026103 PMC4957599__F2 Molecular mechanism of disc cell senescence ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 PMC4880142__F6 Exposure of MCF-7 cells to 10 nM E2 (A) and 1 μM G-1 (B) induced phosphorylation of proteins involved in cellular processes associated with cell cycle although the specific phosphorylation profiles varied ENSG00000182481 ENSG00000181163 ENSG00000171940 ENSG00000115806 ENSG00000151929 ENSG00000129518 ENSG00000147654 ENSG00000160049 ENSG00000076554 ENSG00000138757 ENSG00000136997 ENSG00000111707 ENSG00000165119 ENSG00000100664 ENSG00000165795 ENSG00000096063 ENSG00000065978 ENSG00000138674 ENSG00000060491 ENSG00000204673 ENSG00000121060 ENSG00000136448 ENSG00000124171 ENSG00000130669 ENSG00000084774 PMC8718269__F4 Functions of PARP5a/b, PARP7, and PARP9 in viral infection ENSG00000143799 ENSG00000183735 ENSG00000117020 ENSG00000163840 ENSG00000115415 ENSG00000077348 ENSG00000276561 PMC8492287__F6 Novel Identified Peptide Hormone “Metabolitin” Attenuates Lipid Absorption in the Small Intestine of Diabetic Mice with Nonalcoholic Fatty Liver Disease by Regulating Neurotensin and AMPK Signaling Pathway ENSG00000135218 ENSG00000026103 PMC9932084__F10 Work model of 181-Rik function in the mitochondria-mediated inflammatory response of microglia ENSG00000278718 ENSG00000162711 ENSG00000243317 ENSG00000175567 PMC3494185__F7 Hypothetical schematic of the roles of KPNA2 and E2F1 in NSCLC ENSG00000101868 ENSG00000182481 ENSG00000109814 ENSG00000065328 ENSG00000070495 ENSG00000014138 ENSG00000122512 PMC6880611__F1 Insulin signaling and insulin resistance in MetS and skin diseases PMC7248199__F7 Putative pathway showing regulatory relationships of key genes to NFKB activation transcriptionally regulated by NLRC5 ENSG00000187554 ENSG00000107485 ENSG00000168610 ENSG00000113525 ENSG00000064012 ENSG00000276561 ENSG00000189067 PMC7278913__F3 SMAD4 loss and potential therapeutic strategies in SMAD4 signaling PMC3380218__F1 The Drosophila IMD and mammalian TNF signalling pathways ENSG00000102871 ENSG00000173039 ENSG00000162924 ENSG00000168040 ENSG00000127191 ENSG00000064012 PMC4430528__F5 Sharing and Specificity of Co-expression Networks across 35 Human Tissues ENSG00000291603 ENSG00000122224 ENSG00000168758 ENSG00000020633 ENSG00000010278 ENSG00000213626 ENSG00000118971 ENSG00000010310 ENSG00000100385 ENSG00000177272 ENSG00000161791 ENSG00000181847 ENSG00000107485 ENSG00000126838 ENSG00000139626 PMC4513088__F8 Proposed signaling pathways of PS1-induced apoptosis ENSG00000132906 ENSG00000197746 ENSG00000171791 ENSG00000168040 ENSG00000164305 PMC7088895__F1 TGFB and BMPs signaling pathways ENSG00000170365 ENSG00000198793 ENSG00000120693 PMC9942973__F9 Working model for HCMV-induced SOCS3 upregulation in NPCs ENSG00000128342 ENSG00000181827 PMC12206628__F6 Signaling pathways of NK cell-mediated cytotoxicity and apoptosis ENSG00000104689 ENSG00000101109 ENSG00000196591 ENSG00000284100 ENSG00000169032 ENSG00000180644 ENSG00000163737 ENSG00000137801 ENSG00000142166 ENSG00000179295 ENSG00000092871 ENSG00000135077 ENSG00000088888 ENSG00000149269 ENSG00000010810 ENSG00000189403 ENSG00000124181 PMC4862578__F1 Illustration of negative regulators of CaN-NFAT signaling pathway in cardiac hypertrophy ENSG00000166869 ENSG00000159200 ENSG00000187446 ENSG00000117602 PMC8292061__F5 Exploring the Mechanism of Scutellaria baicalensis Georgi Efficacy against Oral Squamous Cell Carcinoma Based on Network Pharmacology and Molecular Docking Analysis ENSG00000180210 ENSG00000122025 ENSG00000087245 ENSG00000104365 ENSG00000157404 ENSG00000171105 ENSG00000070831 ENSG00000291971 ENSG00000164362 ENSG00000112715 ENSG00000146648 PMC3697783__F8 Wnt signaling pathway ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000100387 ENSG00000134982 ENSG00000113558 ENSG00000168036 ENSG00000115718 PMC7028010__F1 UPR activation mediates beta-cell survival ENSG00000128272 ENSG00000144895 ENSG00000265972 ENSG00000100219 ENSG00000168610 PMC6901278__F3 Regulatory network hubs are related to neurogenesis ENSG00000154764 ENSG00000221866 ENSG00000136535 ENSG00000184347 ENSG00000148400 ENSG00000179242 ENSG00000188064 ENSG00000189056 ENSG00000137845 ENSG00000130751 ENSG00000106003 ENSG00000104327 ENSG00000007168 ENSG00000187957 ENSG00000146648 ENSG00000075213 ENSG00000101752 PMC5966770__F2 Biosynthesis and consumption of NAD+ ENSG00000077009 ENSG00000105835 ENSG00000291814 ENSG00000106733 PMC3278831__F4 Sample subnetwork formation ENSG00000149311 ENSG00000163914 PMC7731343__F7 Differentially expressed protein (DEP) expression in the plasma of rainbow trout exposed to thermal stress PMC9141839__F7 Activation of Esterase D by FPD5 Inhibits Growth of A549 Lung Cancer Cells via JAB1/p53 Pathway ENSG00000117399 ENSG00000134690 PMC9547461__F2 Emerging role of pyroptosis in pediatric cancers: from mechanism to therapy ENSG00000278718 ENSG00000124256 ENSG00000137275 ENSG00000102871 ENSG00000091592 ENSG00000091106 ENSG00000168040 ENSG00000127191 ENSG00000082512 ENSG00000120868 ENSG00000168404 ENSG00000064012 ENSG00000285379 PMC4818113__F6 Biogenesis of reactive sulfur species for signaling by hydrogen sulfide oxidation pathways ENSG00000182511 ENSG00000188158 PMC4938759__F1 Mammalian target of rapamycin complex (mTOR) pathway modulates blood-testis barrier (BTB) function through F-actin organization and gap junction ENSG00000155792 ENSG00000167965 ENSG00000100985 PMC12106265__F3 ER stress in DILI ENSG00000128272 ENSG00000100219 ENSG00000127191 PMC7765045__F1 Main pharmacogenetic biomarkers associated with conventional synthetic disease-modifying antirheumatic drug (csDMARD) treatment ENSG00000228716 ENSG00000137364 ENSG00000173638 ENSG00000035928 ENSG00000118777 ENSG00000102967 PMC9547461__F7 Emerging role of pyroptosis in pediatric cancers: from mechanism to therapy ENSG00000278718 ENSG00000125538 ENSG00000145649 ENSG00000189403 ENSG00000073605 PMC7020065__F5 During pregnancy recognition (PR) in cattle conceptus produced IFNT increased expression of type I IFN-stimulated genes (ISGs) in the uterine endometrium and increased prostaglandin (PG) production facilitates these effects ENSG00000122420 ENSG00000050628 ENSG00000125384 ENSG00000115267 ENSG00000027697 ENSG00000073756 ENSG00000276561 ENSG00000142166 ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000095303 ENSG00000131323 ENSG00000160951 ENSG00000164342 PMC7693003__F2 Role of FDFT1 in the biosynthesis of cholesterol, structure and roles of lipid rafts and regulation of FDFT1 by SREBP2 ENSG00000113161 PMC3108467__F4 IFN signaling pathway coded with identified proteins on day 7 postinfection ENSG00000068079 ENSG00000128050 ENSG00000213928 ENSG00000111537 ENSG00000117228 ENSG00000033800 ENSG00000125347 PMC4274748__F4 Inactivating gene fusions of NF1 in lung cancer ENSG00000091536 ENSG00000087095 ENSG00000108671 ENSG00000196712 ENSG00000108591 PMC5381110__F6 Quantitative proteomics by SWATH-MS reveals sophisticated metabolic reprogramming in hepatocellular carcinoma tissues ENSG00000284320 ENSG00000291958 ENSG00000092621 ENSG00000178445 PMC7693003__F1 Biosynthesis of cholesterol and its derivatives ENSG00000070831 PMC7219953__F1 Proposed mechanism of action underlying the fast and sustained antidepressant effects of ketamine ENSG00000198793 PMC2834833__F3 GSK3: a multifaceted kinase in Wnt signaling ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC8535772__F3 Glutathione in Mediating Abscisic Acid Signaling and Its Regulation of Seed Dormancy and Drought Tolerance ENSG00000138443 ENSG00000075643 ENSG00000163788 PMC6064680__F1 Model cell illustrating the Gq-mER signaling pathway in hypothalamic neurons ENSG00000182533 ENSG00000115138 PMC11749302__F3 Selected results of natural product-based nanomedicines against liver disease ENSG00000069482 ENSG00000117400 ENSG00000104517 PMC8607235__F4 SOCS proteins and their roles in the development of glioblastoma ENSG00000081913 ENSG00000115415 ENSG00000138798 ENSG00000122779 ENSG00000168610 PMC7498629__F2 Role of FoxO signaling in activating ubiquitin-proteolysis and autophagy-lysosomal pathway when skeletal muscle is immobilized ENSG00000090432 ENSG00000177169 ENSG00000116688 ENSG00000198793 ENSG00000096717 ENSG00000214253 PMC9464948__F6 Luteolin induces pyroptosis in HT-29 cells by activating the Caspase1/Gasdermin D signalling pathway ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC11702054__F2 TRIB2 in the physiological proliferation of granulosa cells, myoblasts, naive T cells, and thymocytes, and pathological proliferation of VSMCs ENSG00000071575 ENSG00000198793 ENSG00000020633 PMC11702054__F3 TRIB2 in the lung cancer cell, liver cancer cell, and leukemia cell proliferation ENSG00000071575 ENSG00000132109 ENSG00000078399 ENSG00000198742 ENSG00000167468 ENSG00000072274 ENSG00000168036 ENSG00000168610 ENSG00000196628 ENSG00000143995 PMC8607235__F5 SOCS proteins and their roles in the development of glioblastoma ENSG00000033327 ENSG00000099985 ENSG00000138798 PMC2656900__F1 Working model for Eph receptor function in tumor promotion and tumor suppression ENSG00000146648 PMC11702054__F5 TRIB2 in melanoma cell, colorectal cancer cell, ovarian cancer cell, and osteosarcoma cell proliferation ENSG00000071575 ENSG00000168036 ENSG00000253352 PMC4919052__F6 Impact of Intramammary Escherichia coli Challenge on Liver and Mammary Transcriptome and Cross-Talk in Dairy Cows during Early Lactation Using RNAseq ENSG00000109819 ENSG00000171855 ENSG00000111537 ENSG00000116044 ENSG00000125538 ENSG00000136997 ENSG00000168310 ENSG00000125347 ENSG00000112115 ENSG00000168610 ENSG00000113525 ENSG00000106546 PMC4919052__F7 Impact of Intramammary Escherichia coli Challenge on Liver and Mammary Transcriptome and Cross-Talk in Dairy Cows during Early Lactation Using RNAseq ENSG00000109819 ENSG00000100219 ENSG00000198911 PMC4064697__F2 Schematic summary of the photoneuroendocrine control of food intake and body weight ENSG00000143320 ENSG00000165409 ENSG00000134200 PMC4686085__F4 Axon guidance pathway involving neuropilin 1 ENSG00000113456 ENSG00000182511 ENSG00000137601 ENSG00000070831 ENSG00000173156 ENSG00000010810 ENSG00000154134 ENSG00000185008 ENSG00000288455 ENSG00000075213 ENSG00000121966 PMC10136307__F4 Proposed ER-related mechanisms in the induction of autophagy and UPR in B cells ENSG00000177169 ENSG00000110497 ENSG00000198382 ENSG00000128272 ENSG00000144895 ENSG00000101255 ENSG00000100219 ENSG00000171791 ENSG00000145782 ENSG00000057663 PMC8469138__F3A Molecular Biology Networks and Key Gene Regulators for Inflammatory Biomarkers Shared by Breast Cancer Development: Multi-Omics Systems Analysis ENSG00000051523 ENSG00000066294 ENSG00000137078 ENSG00000213928 ENSG00000130528 ENSG00000198851 ENSG00000077522 ENSG00000163599 ENSG00000109943 ENSG00000150637 ENSG00000140416 ENSG00000288250 ENSG00000138378 ENSG00000153283 ENSG00000161921 ENSG00000135114 ENSG00000026508 ENSG00000291555 ENSG00000113263 ENSG00000100504 ENSG00000155657 PMC10136307__F2 Inhibition and induction of autophagy ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000198382 ENSG00000145782 ENSG00000057663 PMC3675677__F1 Insulin-like growth factor type I (IGF-1R) signaling axis ENSG00000106070 ENSG00000169047 ENSG00000198793 ENSG00000140443 PMC4407080__F1 Image of the MAPK signaling pathway painted by KPP according to the imported list of genes differentially expressed in the prostatic carcinoma as compared to normal prostate ENSG00000170458 ENSG00000080823 ENSG00000074266 PMC7487981__F1 Local area (subpathway) of retinol metabolism pathway is highly correlated with ALDH1A1 ENSG00000121207 ENSG00000284807 ENSG00000171234 ENSG00000006757 PMC3774847__F1 Schematic model of GMIP and Slp1/JFC1 regulation of vesicular dynamics and exocytosis in neutrophils PMC7472693__F3 Coordinated regulation of the host NFKB pathway by L ENSG00000175104 PMC7025433__F1 Methionine metabolic pathway ENSG00000116984 PMC10814159__F3 MDM2 and CDK4 pathway regulation ENSG00000135446 PMC3386543__F7 Schematic of C/EBP A/B functions in GCs ENSG00000138798 PMC10814159__F5 Activation of the Hh/GLI signaling pathway ENSG00000171791 ENSG00000128602 PMC4557273__F5 Sperm navigation along helical paths in 3D chemoattractant landscapes ENSG00000145321 PMC9482985__F2 Transcriptional regulation of oil biosynthesis in seed plants: Current understanding, applications, and perspectives ENSG00000074800 ENSG00000285482 PMC5681735__F1 Kynurenine pathway (KP) ENSG00000188676 PMC6041131__F5 Loss of FFAR2 promotes colon cancer by epigenetic dysregulation of inflammation suppressors ENSG00000050165 ENSG00000104332 PMC5040710__F8 Illustration of role of differentially regulated proteins involved in different pathways in rice for sustaining during drought stress ENSG00000062485 PMC9679345__F2 Gap Junction–Mediated Transport of Metabolites Between Stem Cells and Vascular Endothelial Cells ENSG00000178860 ENSG00000183691 ENSG00000172005 ENSG00000174059 ENSG00000237834 PMC7176421__F6 Dynamic Fas signaling network regulates neural stem cell proliferation and memory enhancement ENSG00000198793 ENSG00000026103 PMC9284435__F2 Ferroptosis: Opportunities and Challenges in Treating Endometrial Cancer ENSG00000128272 ENSG00000151012 ENSG00000144554 PMC150458__F3 Known Wnt signaling pathways ENSG00000134982 ENSG00000168036 PMC5862315__F4 HFD activates genes involved in inflammation and tumorigenesis ENSG00000105329 ENSG00000167768 ENSG00000291971 ENSG00000188064 ENSG00000169884 ENSG00000196396 ENSG00000144476 ENSG00000104368 ENSG00000144648 ENSG00000164758 ENSG00000149968 ENSG00000137674 ENSG00000136146 ENSG00000121742 ENSG00000137673 ENSG00000143546 ENSG00000163220 ENSG00000166670 ENSG00000277641 ENSG00000168610 ENSG00000164742 ENSG00000118785 ENSG00000107485 ENSG00000140254 ENSG00000100985 ENSG00000271447 ENSG00000186832 PMC6040091__F4 WNT/Beta-catenin signal transduction pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3978512__F3 Canonical WNT/Beta-catenin signaling genes marked in green are hypermethylated in parous women (suggesting down-regulation of the gene in parous women) ENSG00000087095 ENSG00000127445 ENSG00000156076 ENSG00000137673 ENSG00000291971 ENSG00000134982 ENSG00000026508 ENSG00000168036 ENSG00000104332 ENSG00000196628 PMC4087737__F1 A: The heme biosynthetic pathway ENSG00000182511 ENSG00000102977 PMC4905365__F1 Targeting the lncRNA-dependent noncanonical Hedgehog pathway by LNA in combination with classical Hedgehog pathway inhibitors ENSG00000101751 ENSG00000122966 ENSG00000137077 ENSG00000163914 ENSG00000164690 ENSG00000128602 PMC6402450__EV2 Metabolic Reprogramming in Colon Cancer ENSG00000128050 ENSG00000131473 ENSG00000169710 ENSG00000078237 PMC7915605__F6 Summary of steroidogenic pathways in primary trophoblast cells isolated from human term placenta ENSG00000108786 ENSG00000203857 ENSG00000176387 PMC4128856__F7 Targeting c-Met in melanoma ENSG00000019991 ENSG00000141448 ENSG00000134982 ENSG00000198793 PMC6014489__F1 The Wnt signaling pathway ENSG00000087095 ENSG00000112576 ENSG00000107404 ENSG00000182968 ENSG00000156076 ENSG00000281324 ENSG00000175592 ENSG00000169884 ENSG00000276920 ENSG00000125084 ENSG00000116161 ENSG00000095739 ENSG00000100387 ENSG00000167941 ENSG00000113558 ENSG00000177606 ENSG00000136997 ENSG00000115266 ENSG00000165879 ENSG00000146122 ENSG00000076716 ENSG00000168646 ENSG00000131196 ENSG00000175792 PMC3792350__F1 Overview of peroxisome biogenesis: converging de novo and growth and division models ENSG00000198356 ENSG00000124587 ENSG00000034693 PMC3808934__F1 RLR-mediated pathways of type I interferon and inflammatory responses ENSG00000183735 ENSG00000131323 ENSG00000168040 ENSG00000175104 ENSG00000121060 ENSG00000276561 PMC3808934__F2 Interplay of TLR and RLR signaling ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC8371477__F2 Zebrafish Models in Therapeutic Research of Cardiac Conduction Disease ENSG00000170961 ENSG00000018408 ENSG00000178568 PMC7322959__F3 Differentially expressed genes in SPCs of GATA2 deficiency ENSG00000160789 ENSG00000170027 ENSG00000109805 ENSG00000188690 ENSG00000023697 PMC11002443__F6 Putrescine Upregulates Melanogenesis Through Modulation of MITF Transcription Factor in B16F1 Mouse Melanoma Cells ENSG00000285250 PMC4037312__F3 PI3K/AKT/PTEN signaling, which modulate NOXs-derived ROS ENSG00000198793 ENSG00000168036 PMC3760732__F8 Pathway interactions among HGF/c-Met, PI3K/Akt, and Notch signaling pathways ENSG00000019991 ENSG00000114315 PMC7343183__F8 JNK pathway plays a key role in the immune system of the pea aphid and is regulated by microRNA-184 ENSG00000177606 ENSG00000105227 PMC9042933__F1 NRF2 Expression Under Different Conditions ENSG00000181019 ENSG00000100387 ENSG00000079999 PMC4531138__F2 miRNAs control inflammatory response in ECs ENSG00000166167 ENSG00000108691 ENSG00000107562 ENSG00000163739 ENSG00000127528 ENSG00000096717 ENSG00000175104 ENSG00000143333 ENSG00000184216 ENSG00000136826 ENSG00000121966 ENSG00000137801 PMC5198544__F3 Tissue injected with B. asper venom ENSG00000115008 ENSG00000125538 ENSG00000136869 PMC11639970__F1 WNT and TGF-Beta Pathway Alterations in Early-Onset Colorectal Cancer Among Hispanic/Latino Populations ENSG00000134982 ENSG00000198793 ENSG00000163914 ENSG00000177606 PMC8002238__F1 Cyclophosphamide metabolic pathway (adapted from Jonge et al., 2005 ) ENSG00000165841 ENSG00000197408 PMC3091413__F7 Results of pathway prediction and network modeling showing interactions between genes containing SNPs associated with risk for breast cancer and genes involved in the Notch signaling and other biological pathways ENSG00000135547 ENSG00000105329 ENSG00000095015 ENSG00000170606 ENSG00000277273 ENSG00000171462 ENSG00000145386 ENSG00000112715 ENSG00000164305 ENSG00000134480 ENSG00000012048 ENSG00000136807 ENSG00000103479 ENSG00000129757 ENSG00000150991 ENSG00000188313 ENSG00000074181 ENSG00000078747 ENSG00000139372 ENSG00000123374 ENSG00000051180 ENSG00000109670 ENSG00000132906 ENSG00000103266 ENSG00000104365 ENSG00000005339 ENSG00000101057 ENSG00000064393 ENSG00000184916 ENSG00000127191 ENSG00000145604 ENSG00000066468 ENSG00000017797 ENSG00000133961 ENSG00000288325 ENSG00000080839 ENSG00000127616 PMC3091413__F5 Results of pathway prediction and network modeling showing interactions between genes containing SNPs associated with risk for breast cancer and genes involved in the Notch signaling and other biological pathways based on the Asian population ENSG00000135547 ENSG00000171444 ENSG00000035928 ENSG00000145386 ENSG00000089159 ENSG00000012048 ENSG00000136807 ENSG00000103479 ENSG00000150991 ENSG00000074181 ENSG00000283780 ENSG00000136997 ENSG00000123374 ENSG00000108821 ENSG00000139687 ENSG00000253729 ENSG00000109670 ENSG00000005339 ENSG00000148400 ENSG00000184916 ENSG00000145604 ENSG00000110395 ENSG00000010810 ENSG00000132646 ENSG00000133961 ENSG00000149554 ENSG00000080839 ENSG00000127616 PMC3091413__F6 Results of pathway prediction and network modeling showing interactions between genes containing SNPs associated with risk for breast cancer and genes involved in the Notch signaling and other biological pathways ENSG00000035928 ENSG00000145386 ENSG00000067369 ENSG00000124762 ENSG00000012048 ENSG00000175054 ENSG00000150991 ENSG00000074181 ENSG00000170430 ENSG00000132383 ENSG00000123374 ENSG00000051180 ENSG00000139687 ENSG00000064012 ENSG00000253729 ENSG00000109670 ENSG00000005339 ENSG00000148400 ENSG00000187741 ENSG00000149311 ENSG00000145604 ENSG00000132646 ENSG00000165392 ENSG00000133961 ENSG00000149554 ENSG00000095002 ENSG00000178568 ENSG00000127616 ENSG00000136936 PMC3091413__F4 Results of pathway prediction and network modeling showing interactions between genes containing SNPs associated with risk for breast cancer and genes involved in the Notch signaling and other biological pathways based on the Caucasian population ENSG00000135547 ENSG00000035928 ENSG00000145386 ENSG00000164305 ENSG00000183765 ENSG00000134899 ENSG00000103479 ENSG00000175054 ENSG00000074181 ENSG00000283780 ENSG00000263528 ENSG00000136997 ENSG00000132383 ENSG00000167967 ENSG00000123374 ENSG00000101138 ENSG00000132535 ENSG00000139687 ENSG00000253729 ENSG00000109670 ENSG00000171189 ENSG00000148400 ENSG00000196954 ENSG00000213341 ENSG00000086015 ENSG00000127191 ENSG00000149311 ENSG00000145604 ENSG00000132646 ENSG00000165392 ENSG00000026508 ENSG00000197299 ENSG00000133961 ENSG00000095002 ENSG00000080839 ENSG00000127616 ENSG00000136936 PMC5620326__F4 Roles of signal transducer and activator of transcription factor 3 in tumor angiogenesis ENSG00000086991 ENSG00000168610 PMC8136131__F10 Esomeprazole attenuates inflammatory and fibrotic response in lung cells through the MAPK/Nrf2/HO1 pathway ENSG00000169071 ENSG00000135111 ENSG00000088256 ENSG00000175567 ENSG00000163737 ENSG00000137764 ENSG00000104213 ENSG00000121068 ENSG00000105270 ENSG00000122691 ENSG00000160796 ENSG00000198759 ENSG00000136869 ENSG00000125968 ENSG00000130513 ENSG00000125266 ENSG00000101955 ENSG00000163453 ENSG00000132170 ENSG00000211445 ENSG00000115884 ENSG00000160867 ENSG00000156427 ENSG00000291748 ENSG00000106624 ENSG00000146648 PMC5158012__F3 Triggering Receptor Expressed on Myeloid Cells and 5′Adenosine Monophosphate-activated Protein kinase in the Inflammatory Response: A Potential Therapeutic Target ENSG00000172936 ENSG00000005381 PMC5158012__F4 Triggering Receptor Expressed on Myeloid Cells and 5′Adenosine Monophosphate-activated Protein kinase in the Inflammatory Response: A Potential Therapeutic Target ENSG00000213658 PMC5099115__F3 IGF-1R Signaling ENSG00000140443 PMC4906927__F2 Schematic of the RBPJ structure and domains demonstrating the domain organization of RBPJ, NICD and MAM ENSG00000169814 ENSG00000168214 PMC5580472__F1 Extrinsic and intrinsic apoptotic pathways ENSG00000173992 ENSG00000120868 ENSG00000168040 ENSG00000127191 ENSG00000047597 PMC3405333__F9 Pathway component for cell cycle G2/M DNA damage checkpoint regulation ENSG00000012048 ENSG00000198576 PMC5283822__F2 Ubiquitin signaling during lesion recognition in the GG-NER pathway ENSG00000158290 ENSG00000134574 ENSG00000164164 ENSG00000162402 ENSG00000100387 ENSG00000167986 ENSG00000139842 ENSG00000247746 ENSG00000157450 PMC5283822__F3 Ubiquitylation events during TC-NER ENSG00000069869 ENSG00000100387 ENSG00000163945 ENSG00000167986 ENSG00000139842 ENSG00000128908 ENSG00000114115 PMC5329931__F2 Effects of TAMs on tumor progression ENSG00000143546 ENSG00000275385 PMC8275893__F2 TCF7L2 in Type 2 Diabetes ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000026508 PMC8275893__F3 TCF7L2 in Type 2 Diabetes ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC4736120__F1 Approaches for xylose-based fatty alcohol production and improvement ENSG00000122966 ENSG00000172005 ENSG00000026103 ENSG00000158125 PMC8254604__F2 Key Signaling Pathways in Psoriasis: Recent Insights from Antipsoriatic Therapeutics ENSG00000162594 ENSG00000175104 ENSG00000127191 ENSG00000168610 ENSG00000123268 ENSG00000106546 ENSG00000079999 PMC2947794__F1 Examination of Association to Autism of Common Genetic Variation in Genes Related to Dopamine ENSG00000123454 ENSG00000171759 PMC9231384__F5 tiRNAs: Insights into Their Biogenesis, Functions, and Future Applications in Livestock Research ENSG00000134982 ENSG00000104290 ENSG00000168036 PMC7067536__F7 Hepatitis C Virus Infection of Human Thyrocytes: Metabolic, Hormonal, and Immunological Implications ENSG00000137812 ENSG00000162496 ENSG00000166189 ENSG00000174276 ENSG00000184371 ENSG00000107902 ENSG00000184792 ENSG00000198265 ENSG00000277140 ENSG00000105698 ENSG00000139832 ENSG00000178919 PMC9231384__F6 tiRNAs: Insights into Their Biogenesis, Functions, and Future Applications in Livestock Research ENSG00000100906 ENSG00000135387 PMC3293935__F4 Known apoptotic targets of P53 ENSG00000132906 ENSG00000174307 ENSG00000168209 ENSG00000112378 ENSG00000164305 ENSG00000026103 PMC4370592__F6 Developmental Exposure to Estrogen Alters Differentiation and Epigenetic Programming in a Human Fetal Prostate Xenograft Model ENSG00000132906 ENSG00000002330 ENSG00000167034 ENSG00000124762 PMC6945997__F3 Recognition of Candida species is mediated by Toll-like receptors (TLRs), C-type lectin receptors (CLRs) and nucleotide-binding oligomerization domain (NOD) receptors ENSG00000162711 ENSG00000167207 ENSG00000187796 ENSG00000125538 PMC11714729__F3 Hedgehog signaling pathway ENSG00000164690 ENSG00000128602 PMC11592846__F4 Lactic acid in macrophages during inflammation as a signaling molecule ENSG00000148942 ENSG00000262217 ENSG00000118520 ENSG00000100985 ENSG00000112715 ENSG00000168610 PMC5736922__F1 Genomic and non-genomic effects of androgens in the cardiovascular system: clinical implications ENSG00000086991 ENSG00000173612 PMC8817698__F3 MAVS Immune Recognition Pathway in Viral Infection and Sepsis ENSG00000183735 ENSG00000088888 ENSG00000276561 PMC8817698__F4 MAVS Immune Recognition Pathway in Viral Infection and Sepsis ENSG00000088888 ENSG00000165312 ENSG00000160703 PMC9701731__F1 Presentation and integration of multiple signals that modulate oligodendrocyte lineage progression and myelination ENSG00000184221 ENSG00000134853 ENSG00000205927 ENSG00000100146 ENSG00000196712 PMC9617479__F1 Metabolic features of innate lymphoid cells ENSG00000131473 ENSG00000075239 ENSG00000115419 ENSG00000062485 PMC4530265__F8 Proposed schematic showing targets of edible bird's nest (EBN) action in the insulin signaling pathway ENSG00000104365 ENSG00000171105 ENSG00000067606 ENSG00000198793 PMC9617479__F2 Metabolic features of innate lymphoid cells ENSG00000131473 ENSG00000198793 ENSG00000136997 ENSG00000075239 PMC4408865__F1 An example of positive and negative regulation of the Ifn-signalling pathway ENSG00000132109 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000140968 ENSG00000172005 ENSG00000172936 ENSG00000171206 ENSG00000136869 ENSG00000175104 ENSG00000164342 PMC9617479__F3 Metabolic features of innate lymphoid cells ENSG00000198793 ENSG00000285482 ENSG00000118520 ENSG00000026103 PMC10740511__F4 Identification of Potential miRNA–mRNA Regulatory Network Associated with Growth and Development of Hair Follicles in Forest Musk Deer ENSG00000004975 ENSG00000005339 ENSG00000148400 ENSG00000108773 ENSG00000196591 ENSG00000196782 ENSG00000100060 ENSG00000178498 ENSG00000184916 ENSG00000135144 ENSG00000090932 ENSG00000110042 ENSG00000091073 ENSG00000143801 ENSG00000163840 ENSG00000184384 ENSG00000196498 ENSG00000124232 ENSG00000273529 ENSG00000133961 ENSG00000161202 ENSG00000114315 ENSG00000114166 ENSG00000100603 PMC10740511__F5 Identification of Potential miRNA–mRNA Regulatory Network Associated with Growth and Development of Hair Follicles in Forest Musk Deer ENSG00000004975 ENSG00000107404 ENSG00000005339 ENSG00000148400 ENSG00000108773 ENSG00000196591 ENSG00000109851 ENSG00000100060 ENSG00000178498 ENSG00000184916 ENSG00000175029 ENSG00000110042 ENSG00000091073 ENSG00000143801 ENSG00000163840 ENSG00000074181 ENSG00000184384 ENSG00000196498 ENSG00000124232 ENSG00000273529 ENSG00000133961 ENSG00000161202 ENSG00000114166 ENSG00000100603 PMC12135473__F2 Dual roles of AIF in cell death and in vital mitochondrial functions ENSG00000163528 PMC7761568__F2 Influence network of TCR signalling ENSG00000100811 ENSG00000165030 ENSG00000163599 ENSG00000197272 ENSG00000049768 ENSG00000168610 ENSG00000150637 ENSG00000138378 ENSG00000089692 ENSG00000111537 ENSG00000213658 ENSG00000178573 ENSG00000181847 PMC9583131__F2 Selective serotonin reuptake inhibitors and inflammatory bowel disease; Beneficial or malpractice ENSG00000170458 ENSG00000125538 ENSG00000164342 PMC6629960__F1 Air pollution and ultraviolet radiation (UVR) on the skin ENSG00000171759 ENSG00000140465 ENSG00000106546 PMC9583131__F3 Selective serotonin reuptake inhibitors and inflammatory bowel disease; Beneficial or malpractice ENSG00000125538 ENSG00000106546 PMC5429641__F7 Neuroprotective action of MMP-9 in preventing ABeta-mediated impairment of the insulin survival pathway ENSG00000169047 PMC5607574__F1 Schematic of Hh signal transduction in Drosophila and vertebrates ENSG00000166813 ENSG00000128602 PMC8081860__F3 Lipoarabinomannan as a Point-of-Care Assay for Diagnosis of Tuberculosis: How Far Are We to Use It? ENSG00000078081 ENSG00000172936 ENSG00000150455 ENSG00000005381 PMC4564046__F1 Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution ENSG00000181019 ENSG00000178573 ENSG00000023909 ENSG00000079999 PMC8081860__F4 Lipoarabinomannan as a Point-of-Care Assay for Diagnosis of Tuberculosis: How Far Are We to Use It? ENSG00000291603 ENSG00000213658 ENSG00000198851 ENSG00000198793 ENSG00000172936 PMC7793839__F1 Toll-like receptor 4 (TLR4) signaling pathway ENSG00000183735 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC3274489__F1 Overview of the mevalonate pathway ENSG00000039537 ENSG00000166278 PMC3384380__F2 Schematic depiction of NFKB signaling pathway highlighting FOXP1 target genes ENSG00000226275 ENSG00000077150 ENSG00000291603 ENSG00000138798 ENSG00000196591 ENSG00000197943 ENSG00000111321 ENSG00000150455 ENSG00000127191 ENSG00000198286 PMC6731300__F9 The proposed model ENSG00000174307 ENSG00000271303 PMC3374082__F7 Schematic representation of the data ENSG00000074181 PMC5301050__F1 Cancer Therapies in HIV Cure Research ENSG00000111537 PMC4146420__F1 Prostaglandin synthesis pathway ENSG00000108839 ENSG00000161905 ENSG00000275565 PMC5137279__F4 Pictorial representation of altered GABA receptor signaling due to PCP-SI treatment ENSG00000143149 ENSG00000171723 ENSG00000101438 ENSG00000135018 PMC7198750__F2 Depiction of the cGAS-STING pathway ENSG00000149311 ENSG00000177169 ENSG00000173638 PMC11768203__F2 Virulence factors of Fusobacterium nucleatum ENSG00000023445 ENSG00000181847 ENSG00000163739 ENSG00000172936 ENSG00000136869 PMC8122623__F2 Signaling Pathways in Bone Development and Their Related Skeletal Dysplasia ENSG00000178860 ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000283780 ENSG00000167941 ENSG00000106483 PMC8122623__F3 Signaling Pathways in Bone Development and Their Related Skeletal Dysplasia ENSG00000178860 ENSG00000157933 ENSG00000173786 PMC4783232__F1 MicroRNA deregulation in cancer cells and the tumor microenvironment ENSG00000136997 ENSG00000132510 ENSG00000146648 ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC4959859__F8 Schematic mechanism of L5 on STRA6 cascade suppression and kidney injury ENSG00000138207 PMC7959398__F7 Genomic variants from RNA-seq for goats resistant or susceptible to gastrointestinal nematode infection ENSG00000110395 ENSG00000213658 ENSG00000117091 ENSG00000198851 ENSG00000010810 ENSG00000135446 ENSG00000163599 ENSG00000113263 PMC4587406__F1 Dysregulation of dNTPs in cancer pathogenesis and its targeted therapy ENSG00000175054 PMC11818720__F5 Carbohydrate metabolic pathway diagram ENSG00000196549 ENSG00000184363 PMC4287999__F4 Mechanism of T-helper-17 (Th17) cell-mediated lymphangiogenesis ENSG00000150782 ENSG00000125538 ENSG00000150630 PMC5843405__F3 SUMOylation in representative cancer pathways PMC9288288__F9 Network Pharmacology and Molecular Docking Study of Yupingfeng Powder in the Treatment of Allergic Diseases ENSG00000142192 ENSG00000148798 PMC7325056__F10 Intestinal microecological mechanism of diarrhea caused by Folium sennae extracts ENSG00000138356 PMC10505224__F0 By hindering hnRNPA2B1 from binding to the E3 ubiquitin ligase TRIM21, whose mediated ubiquitin-dependent degradation was thereby inhibited, CRNDE protected the stability of hnRNPA2B1’s high protein expression in CRC ENSG00000122566 ENSG00000132109 PMC7286818__F2 Emerging roles of WBP2 oncogene in human cancers ENSG00000154342 ENSG00000132471 ENSG00000074800 ENSG00000134982 ENSG00000177606 ENSG00000168036 ENSG00000154310 ENSG00000150457 ENSG00000051128 ENSG00000168646 ENSG00000131023 PMC10540449__F3 BMP signaling in the development and regeneration of tooth roots: from mechanisms to applications ENSG00000107779 ENSG00000170365 ENSG00000029559 ENSG00000134982 ENSG00000120693 ENSG00000168036 ENSG00000152591 ENSG00000136826 PMC10540449__F4 BMP signaling in the development and regeneration of tooth roots: from mechanisms to applications ENSG00000107779 ENSG00000170365 ENSG00000137834 ENSG00000148773 ENSG00000134982 ENSG00000120693 ENSG00000168036 ENSG00000164690 PMC10540449__F1 BMP signaling in the development and regeneration of tooth roots: from mechanisms to applications ENSG00000170365 ENSG00000137834 ENSG00000120693 PMC6547588__F1 Spatial regulation of non-amyloidogenic and amyloidogenic processing of APP ENSG00000142192 ENSG00000143801 ENSG00000198087 ENSG00000220205 ENSG00000100083 ENSG00000165527 ENSG00000073921 ENSG00000137845 PMC7011106__F2 Gene-gene interaction among genes associated with atypical antipsychotic-induced lipid disturbances ENSG00000150594 ENSG00000115138 ENSG00000166603 ENSG00000149295 PMC5310915__F12 Analysis of long noncoding RNA and mRNA using RNA sequencing during the differentiation of intramuscular preadipocytes in chicken ENSG00000150991 ENSG00000100979 PMC8786307__F2 Inflammasome-independent signalling by NLR proteins in the intestinal epithelium during CRC ENSG00000163568 ENSG00000198793 ENSG00000160703 ENSG00000142405 ENSG00000168610 ENSG00000276068 PMC9482771__F6 Target genes implicate in inflammation process potentially altered by miR-378 ENSG00000140992 ENSG00000156574 ENSG00000138764 ENSG00000148082 ENSG00000136997 ENSG00000135932 ENSG00000116985 ENSG00000133740 ENSG00000183682 ENSG00000145782 ENSG00000176165 ENSG00000196712 ENSG00000142408 ENSG00000172380 ENSG00000157764 ENSG00000101109 ENSG00000108861 ENSG00000083290 ENSG00000291431 ENSG00000126457 ENSG00000103942 ENSG00000149311 ENSG00000177189 ENSG00000110395 ENSG00000243709 ENSG00000198176 ENSG00000109270 ENSG00000143322 ENSG00000204217 PMC6547588__F5 Involvement of LOAD risk factors at the BBB ENSG00000198087 ENSG00000073921 PMC11583660__F1 Urinary estrogen metabolite before and after values ENSG00000140465 PMC4007997__F4 Molecular pathway analysis of regulated membrane protein changes in RLSCs as they undergo hepatocytic differentiation ENSG00000168028 ENSG00000079112 ENSG00000074800 ENSG00000162458 ENSG00000092820 ENSG00000100079 PMC7198750__F5 Cell interactions in TME engaging the cGAS-STING pathway ENSG00000164430 ENSG00000026103 PMC3524689__F2 Proposed model of OGP(10-14) differentiation signalling ENSG00000105329 ENSG00000117400 PMC4007997__F5 Upstream regulator analysis of membrane protein changes in differently regulated proteins involved in cell-to-cell signaling and interaction ENSG00000110880 ENSG00000049239 ENSG00000019549 ENSG00000095303 ENSG00000072110 ENSG00000092199 PMC5503689__F2 Inflammasome complexes: emerging mechanisms and effector functions ENSG00000164430 ENSG00000163568 ENSG00000125538 ENSG00000136869 PMC7198750__F3 Interaction of the cGAS-STING pathway with other DNA-sensing pathways and its role in cell survival ENSG00000162711 ENSG00000183735 ENSG00000164430 ENSG00000163568 ENSG00000173039 ENSG00000172936 ENSG00000120868 PMC5807683__F5 Pharmacological targeting of KLFs in vascular inflammation ENSG00000198793 ENSG00000127528 ENSG00000096717 ENSG00000136826 PMC6177618__F1 Calcium‐sensing receptor signalling and trafficking ENSG00000152266 ENSG00000087842 PMC1236696__F1 IKK/NFKB signaling pathways ENSG00000104856 ENSG00000125538 ENSG00000111321 ENSG00000162692 PMC6814074__F2 Non-genomic mechanisms of thyroid hormones action in the brain ENSG00000198793 ENSG00000168610 PMC2832144__F11 Proposed model for the signal transduction pathways involved in TGFB1-mediated fibroblast-myofibroblast differentiation ENSG00000170961 ENSG00000138798 ENSG00000026508 ENSG00000146648 PMC8080639__F1 General unfolded protein response pathway during ER stress ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC4167033__F7 IGF but not the EGF signaling pathway is regulated by the NEDD4-PTEN circuitry ENSG00000069869 ENSG00000138798 ENSG00000169047 ENSG00000146648 ENSG00000140443 PMC6028759__F1 Wnt antagonist and secreted frizzled-related protein 5: implications on lipid metabolism, inflammation, and type 2 diabetes mellitus ENSG00000134982 ENSG00000120057 ENSG00000168036 PMC7844295__F2 Biosynthetic pathways of glycerophospholipids in rat hippocampus ENSG00000167107 ENSG00000226275 ENSG00000120915 ENSG00000173599 ENSG00000291994 ENSG00000111684 ENSG00000198670 ENSG00000164398 ENSG00000160216 ENSG00000067113 PMC7844295__F3 Glutathione metabolism ENSG00000174156 ENSG00000133313 ENSG00000167468 ENSG00000143198 ENSG00000277897 ENSG00000112992 PMC9138696__F1 Stressing the Regulatory Role of Long Non-Coding RNA in the Cellular Stress Response during Cancer Progression and Therapy ENSG00000149311 ENSG00000165119 ENSG00000136997 ENSG00000132383 PMC7688371__F1 Oxidative Stress, Folate Receptor Autoimmunity, and CSF Findings in Severe Infantile Autism ENSG00000139287 PMC3816993__F2 Combined miRNAs and transcription factor regulation of inflammation in wound healing ENSG00000005339 ENSG00000109320 ENSG00000162924 ENSG00000125347 ENSG00000163631 ENSG00000185652 ENSG00000108691 ENSG00000239732 ENSG00000177606 ENSG00000136869 ENSG00000185591 ENSG00000175104 ENSG00000184216 ENSG00000026103 PMC7517787__F8 Mechanism model of exogenous MT in delaying the post-harvest decay of wax apples ENSG00000111450 PMC7738628__F5 Selected P5 and/or P10 enriched pathways ENSG00000145864 ENSG00000242689 ENSG00000133056 ENSG00000091972 ENSG00000007312 ENSG00000198793 ENSG00000254445 ENSG00000127472 ENSG00000010671 ENSG00000151834 ENSG00000104327 ENSG00000185652 ENSG00000281614 ENSG00000176884 ENSG00000128272 ENSG00000224320 ENSG00000103490 ENSG00000143507 ENSG00000113327 ENSG00000177606 ENSG00000172936 ENSG00000114739 ENSG00000026103 PMC4039984__F1 Chromatin Landscape and Transcription Factors in T-Cell Programming ENSG00000138378 ENSG00000159216 ENSG00000156127 ENSG00000137265 ENSG00000020633 ENSG00000107485 ENSG00000049768 ENSG00000168610 PMC5220678__F2 Loss of Axin2 can cause MVD by shifting TGFB/SMAD3 pathway toward WNT/Beta-catenin and BMP signaling ENSG00000170365 ENSG00000137834 ENSG00000105329 ENSG00000134982 ENSG00000168036 ENSG00000204217 PMC11889592__F3 miR-34 family has suppressor effects on cancer invasion, proliferation, and metastasis by regulating molecular pathway ENSG00000148400 ENSG00000135446 ENSG00000134853 ENSG00000189403 ENSG00000105810 ENSG00000171791 ENSG00000096717 ENSG00000146648 ENSG00000175305 PMC7738628__F6 “Synaptogenesis signaling” seIPA-path schematic representation in HI exposed P5 (upper panel) and P10 brains (lower panel) ENSG00000142627 ENSG00000108947 ENSG00000108551 ENSG00000198793 ENSG00000161203 ENSG00000179603 ENSG00000021645 ENSG00000187840 ENSG00000067715 ENSG00000176884 ENSG00000128272 ENSG00000140937 ENSG00000130477 ENSG00000125675 ENSG00000150394 ENSG00000154162 ENSG00000120251 ENSG00000182580 ENSG00000164506 PMC3401681__F3 Mesenchymal stem cells (MSCs) may have both growth inhibitory and stimulatory effects on tumours ENSG00000178860 ENSG00000168610 PMC4614032__F1 mTORC1 signaling pathway PMC7401609__F3 Fat metabolism in the subcutaneous fat of yaks under long-term energy stress (ES) ENSG00000042832 ENSG00000149485 ENSG00000087008 ENSG00000165269 ENSG00000164398 ENSG00000079435 ENSG00000177666 ENSG00000101473 ENSG00000123983 ENSG00000177646 PMC10869786__F7 The mechanism by which FXR promotes NSCLC metastasis ENSG00000168610 PMC7401609__F4 Energy balance in yaks under ES by regulating fat metabolism ENSG00000288174 ENSG00000198793 ENSG00000087008 ENSG00000114268 ENSG00000101473 ENSG00000177646 PMC8656796__F5 Therapeutic Efficacy of Variable Biological Effectiveness of Proton Therapy in U-CH2 and MUG-Chor1 Human Chordoma Cell Death ENSG00000082512 ENSG00000177606 ENSG00000131323 ENSG00000127191 ENSG00000186827 PMC8831562__F3 USPs and TGFB signalling ENSG00000135655 ENSG00000083799 ENSG00000134588 PMC10561274__F2 Inflammation associated signaling activated by fractalkine ENSG00000168329 ENSG00000079999 PMC7719135__F2 Mechanism how MCPIP1 and cytokines mutually regulated in macrophages ENSG00000172936 ENSG00000136869 ENSG00000124571 ENSG00000121807 ENSG00000175104 PMC8831562__F2 USPs and NFKB signalling ENSG00000135655 ENSG00000102871 ENSG00000172046 ENSG00000157625 ENSG00000083799 ENSG00000175104 ENSG00000127191 PMC3937154__F5 IPA graphic representation of the network “Cell death and survival, DNA replication, recombination, and repair, cellular response to therapeutics”. Nodes represent genes and lines show the relationship between genes ENSG00000105327 ENSG00000187608 ENSG00000159388 ENSG00000120889 ENSG00000091106 ENSG00000164305 ENSG00000064933 ENSG00000012048 ENSG00000078900 ENSG00000176046 ENSG00000253729 ENSG00000185088 ENSG00000100811 ENSG00000128606 ENSG00000104689 ENSG00000104365 ENSG00000197893 ENSG00000143164 ENSG00000075643 ENSG00000173039 ENSG00000116717 ENSG00000139618 ENSG00000134574 ENSG00000118785 ENSG00000132646 ENSG00000161513 ENSG00000019549 ENSG00000112378 ENSG00000122779 PMC2770888__F2 Targeting EGFR resistance networks in Head and Neck Cancer ENSG00000002330 ENSG00000291971 ENSG00000198793 ENSG00000168610 PMC7870996__F1 Dual regulatory effects of TRAP1 on the mitochondrial apoptotic pathway ENSG00000108582 ENSG00000128272 ENSG00000144895 PMC7396304__F1 Quantitative Measurement of Redox State in Human Brain by 31P MRS at 7T with Spectral Simplification and Inclusion of Multiple Nucleotide Sugar Components in Data Analysis ENSG00000146701 PMC7453310__F3 Alternative splicing regulation of the oncogenic MYC and RAS-MAPK pathways ENSG00000096063 ENSG00000136997 ENSG00000146648 PMC11021402__F5 Fe and S binding by ISCU2 at consecutive stages of de novo [2Fe-2S] cluster biosynthesis ENSG00000267673 PMC6918076__F6 Schematic illustration of AHR activation modulating HIV-1 transcription ENSG00000136807 ENSG00000106546 PMC7765317__F2 Nuclear factor-E2-related factor-2 (NRF2) pathway exerts antifibrotic effects ENSG00000181019 PMC7765317__F3 Reactive oxygen species (ROS) trigger fibrosis via several inflammatory pathways ENSG00000162711 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000265972 PMC4710564__F7 Specialized pro-resolving mediators (SPMs) inhibit human B-cell IgE production ENSG00000105639 PMC7340996__F2 Structure of the filaments containing Septins 7/9b/11 and Jun N-terminal kinase signaling pathway ENSG00000122545 PMC12210160__F1 Anti-hepatitis B virus hepatic innate immunity in hepatocytes ENSG00000088888 ENSG00000125538 ENSG00000172005 ENSG00000172936 ENSG00000164342 PMC5514694__F9 Coordinating reactions in the intestine elicited by LGG in response to S ENSG00000111537 ENSG00000168610 ENSG00000115009 ENSG00000112486 PMC2820234__F3 Suggested signaling of the early stages of 1,25D-induced monocytic differentiation ENSG00000170458 PMC8314387__F2 Signaling Pathways Involved in Diabetic Renal Fibrosis PMC8314387__F3 Signaling Pathways Involved in Diabetic Renal Fibrosis ENSG00000168036 PMC11482726__F10 Working model for NONO positively regulating IRF3-mediated IFNB signaling pathway by detection of PRRSV N ENSG00000183735 ENSG00000088888 PMC5628354__F5 Proposed deglycosylated metabolic pathway of Panax ginseng saponins by rat intestinal microflora ENSG00000180210 ENSG00000139687 PMC7093422__F6 Detailed information of sub-pathway (AGE-RAGE signaling pathway in diabetic complications) in the KEGG ENSG00000087245 ENSG00000115008 ENSG00000165197 ENSG00000105329 ENSG00000109320 ENSG00000137193 ENSG00000007908 ENSG00000171791 ENSG00000121879 ENSG00000168610 ENSG00000164305 ENSG00000161714 ENSG00000117525 ENSG00000117020 ENSG00000115415 ENSG00000177606 ENSG00000150907 ENSG00000108821 ENSG00000162692 ENSG00000131196 PMC9143056__F2 Inflammation by Plant-Derived Nutraceuticals in Tendinitis ENSG00000168610 PMC5056326__F1 Epidermal growth factor receptor signaling along with co-activated other receptor tyrosine kinases ENSG00000157764 ENSG00000198793 ENSG00000121879 ENSG00000146648 PMC5056326__F2 Possible resistance pathways to epidermal growth factor receptor blockade; gain of mutations in KRAS, BRAF, and PIK3CA and upregulation of other receptor tyrosine kinases ENSG00000124102 ENSG00000157764 ENSG00000198793 ENSG00000146648 PMC3518557__F1 Targets and structure of compstatin ENSG00000182326 PMC8666287__F6 Osteoblasts impair cholesterol synthesis in chondrocytes via Notch1 signalling ENSG00000148400 PMC3696549__F10 Reciprocal regulation by TLR4 and TGFB in tumor-initiating stem-like cells ENSG00000198793 ENSG00000136869 ENSG00000136231 PMC3552454__F4 Advances in graft-versus-host disease biology and therapy ENSG00000167207 ENSG00000115415 ENSG00000134982 ENSG00000172936 PMC8460989__F8 Exosomes Transport Anti-Human Immunodeficiency Virus Factors from Human Cervical Epithelial Cells to Macrophages ENSG00000187608 ENSG00000089127 ENSG00000183486 ENSG00000164342 PMC7313221__F4 Main mechanisms involved in the development of HCC ENSG00000130649 ENSG00000172936 ENSG00000136869 PMC4544723__F7 Proposed schematic showing targets of EBN action in the insulin signaling pathway ENSG00000104365 ENSG00000171105 ENSG00000121879 PMC8530523__F3 Epigenetic regulation of energy metabolism in obesity ENSG00000147162 ENSG00000077463 ENSG00000096717 PMC2631402__F4 The Legionella pneumophila replication vacuole: making a cozy niche inside host cells ENSG00000167207 ENSG00000073578 ENSG00000106100 PMC4023801__F2 Proposed metabolic activation pathway of GS-6620 ENSG00000172831 ENSG00000169567 ENSG00000262243 PMC11613313__F2 Endometrial Receptivity Affected by Fibroids ENSG00000253293 ENSG00000170365 ENSG00000005073 ENSG00000148926 ENSG00000204217 PMC6192166__F3 Proteomics and phosphoproteomics driven identification of the aberrant regulation of signalling pathways leading to poor patient survival ENSG00000102606 ENSG00000291971 ENSG00000115904 ENSG00000101306 ENSG00000168610 ENSG00000089159 ENSG00000160691 ENSG00000117020 ENSG00000126247 ENSG00000115415 ENSG00000169750 ENSG00000148082 ENSG00000163914 ENSG00000177606 ENSG00000166501 ENSG00000137076 ENSG00000124181 ENSG00000160293 PMC5836465__F3 Unfolded protein response ENSG00000128272 ENSG00000144895 ENSG00000171791 ENSG00000127191 PMC3528779__F6 Global Effect of Inauhzin on Human p53-Responsive Transcriptome ENSG00000149311 ENSG00000175054 ENSG00000136997 ENSG00000123374 ENSG00000112378 ENSG00000145020 ENSG00000164305 PMC12131027__F5 Schematic model illustrating potential pathways after PRRSV infection in PAMs with identified DEPs based on our study ENSG00000143390 ENSG00000120837 ENSG00000213928 ENSG00000187608 ENSG00000183486 ENSG00000157601 ENSG00000185745 ENSG00000273686 ENSG00000172183 ENSG00000019582 ENSG00000101082 ENSG00000183735 ENSG00000105397 ENSG00000115415 ENSG00000107201 ENSG00000131323 ENSG00000138760 ENSG00000164342 PMC9654795__F1 Ferroptosis: A New Development Trend in Periodontitis ENSG00000168003 ENSG00000186575 ENSG00000135423 ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000073756 PMC10608450__F5 Protein–protein interactions between 341 members of antimicrobial peptides in Trachinotus ovatus ENSG00000145824 ENSG00000170890 ENSG00000142192 ENSG00000175868 ENSG00000156110 ENSG00000130287 PMC3925772__F7 Using Optogenetics to Interrogate the Dynamic Control of Signal Transmission by the Ras/Erk Module ENSG00000291971 ENSG00000198793 ENSG00000164327 ENSG00000168610 PMC5275750__F1 Cancer Cell Metabolism and the Modulating Effects of Nitric Oxide ENSG00000124102 ENSG00000134086 ENSG00000198793 PMC6492140__F1 Global and specific regulation of translation initiation ENSG00000100664 PMC5584588__F7 Stimulation of RNA Polymerase II ubiquitination and degradation by yeast mRNA 3’-end processing factors is a conserved DNA damage response in eukaryotes ENSG00000100387 PMC2071927__F2 TUNING IMMUNE TOLERANCE WITH VASOACTIVE INTESTINAL PEPTIDE: A NEW THERAPEUTIC APPROACH FOR IMMUNE DISORDERS ENSG00000111537 ENSG00000170458 ENSG00000115415 ENSG00000146469 ENSG00000136869 ENSG00000125347 PMC8740192__F1 Myostatin on the Growth and Development of Skeletal Muscle ENSG00000111049 ENSG00000198793 PMC8339209__F2 Recent Progresses in the Treatment of Osteoporosis ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000177606 ENSG00000168036 ENSG00000185591 PMC8598918__F2 Receptor tyrosine kinases as druggable targets in glioblastoma: Do signaling pathways matter? ENSG00000136158 ENSG00000146648 ENSG00000121966 PMC8598918__F1 Receptor tyrosine kinases as druggable targets in glioblastoma: Do signaling pathways matter? ENSG00000146648 ENSG00000196712 PMC2360352__F1 Schematic depicting the central role of HER3 in mediating PI3K/Akt signalling downstream of the HER family ENSG00000002330 ENSG00000198793 ENSG00000146648 PMC4699279__F1 Gliadin peptides pass through the epithelial barrier paracellularly or transcellularly ENSG00000186810 ENSG00000134982 ENSG00000172936 ENSG00000146648 PMC8203646__F8 Meta-analysis of gene signatures and key pathways indicates suppression of JNK pathway as a regulator of chemo-resistance in AML ENSG00000162711 ENSG00000150782 ENSG00000125538 PMC7718059__F8 KEGG pathway enrichment of the S100 genes and their significantly related genes selected from the top 5 module analysis ENSG00000002330 PMC11280316__F8 Suggested schematic illustration of the mechanism by which crocin could induce cell survival and exert anti-oxidative and anti-inflammatory effects in stressed cardiomyocytes ENSG00000117525 ENSG00000181019 ENSG00000108960 ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000079999 PMC5581122__F7 Hypertriglyceridemia in female rats during pregnancy induces obesity in male offspring via altering hypothalamic leptin signaling ENSG00000198576 ENSG00000115138 ENSG00000166603 PMC8235527__F1 Review of PP2A Tumor Biology and Antitumor Effects of PP2A Inhibitor LB100 in the Nervous System PMC5796908__F1 Activated endothelial cells modulate allogenic T lymphocyte activity ENSG00000111537 PMC6983837__F10 RIG-I activation in the context of influenza infection ENSG00000088888 ENSG00000121060 PMC9220936__F2 MicroRNAs in the Regulation of Solute Carrier Proteins Behind Xenobiotic and Nutrient Transport in Cells ENSG00000168003 ENSG00000151012 ENSG00000198793 PMC9300056__F3 Plant endoplasmic reticulum UPRome: A repository and pathway browser for genes involved in signaling networks linked to the endoplasmic reticulum ENSG00000100934 ENSG00000138674 ENSG00000105251 PMC4621122__F8 Hypothesized model for E4-ORF1-induced constitutive Myc protein expression mediated by EGFR, InsR/IGF1R, and PI3K ENSG00000171105 ENSG00000198793 ENSG00000136997 ENSG00000146648 ENSG00000140443 PMC9300056__F2 Plant endoplasmic reticulum UPRome: A repository and pathway browser for genes involved in signaling networks linked to the endoplasmic reticulum ENSG00000204463 ENSG00000291973 ENSG00000123908 PMC6421647__F6 hBM-MSCs-Ex treatment alleviates liver fibrosis in both HSCs and liver fibrosis tissues through inhibition of Wnt/Beta-catenin signaling (PPARG, Wnt3a, Wnt10b, Beta-catenin) and the downregulation of downstream gene expression (WISP1, Cyclin D1) ENSG00000154342 ENSG00000169884 ENSG00000168036 PMC7461110__F1 Cellular Responses to Platinum-Based Anticancer Drugs and UVC: Role of p53 and Implications for Cancer Therapy ENSG00000149311 ENSG00000175054 ENSG00000135423 ENSG00000078237 PMC8859258__F2 Contribution of Epithelial and Gut Microbiome Inflammatory Biomarkers to the Improvement of Colorectal Cancer Patients’ Stratification ENSG00000134982 PMC2971717__F1 Schema of the HER family signaling pathways ENSG00000146648 PMC3904369__F1A Charity begins at home: non-coding RNA contributes to DNA repair ENSG00000149311 ENSG00000012048 ENSG00000196591 ENSG00000113360 PMC3809843__F9 Gremlin regulation of LOXs in TM ENSG00000129038 ENSG00000138131 ENSG00000134013 ENSG00000204217 PMC9367540__F2 Mitochondrial Damage-Associated Molecular Patterns Content in Extracellular Vesicles Promotes Early Inflammation in Neurodegenerative Disorders ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000136869 PMC11955793__F6 hUCB-MNCs inhibit fibrosis process ENSG00000002330 ENSG00000170558 PMC12012570__F2 CIH modulates glial cells in the CNS through various mechanisms ENSG00000079387 ENSG00000162711 ENSG00000172936 ENSG00000047936 PMC8743908__F2 Kynurenine Pathway in Acute Kidney Injury and Chronic Kidney Disease ENSG00000096717 ENSG00000142082 PMC8859258__F4 Contribution of Epithelial and Gut Microbiome Inflammatory Biomarkers to the Improvement of Colorectal Cancer Patients’ Stratification ENSG00000102871 ENSG00000127191 ENSG00000258429 PMC11955793__F5 Anti-inflammatory and antioxidant effects of hUCB-MNCs ENSG00000079999 PMC5973613__F7 Palmitate and insulin counteract glucose-induced thioredoxin interacting protein (TXNIP) expression in insulin secreting cells via distinct mechanisms ENSG00000126266 ENSG00000265972 ENSG00000140443 PMC2515131__F2 Signal transduction events initiated by Kit and FcERI leading to specific mast cell responses, and the integration of these pathways for the synergistic enhancement of mast cell mediator release ENSG00000157404 ENSG00000169291 ENSG00000213658 PMC3908275__F5 Interaction of MSCs and HSCs ENSG00000178860 ENSG00000157404 ENSG00000170558 ENSG00000164690 ENSG00000114315 ENSG00000128602 ENSG00000121966 PMC4392459__F1 The CoA-dependent butanol pathways used for the production of propane in E ENSG00000106546 PMC9032991__F8 Pharmacogenetics of Osteoporosis: A Pathway Analysis of the Genetic Influence on the Effects of Antiresorptive Drugs ENSG00000160752 ENSG00000164219 ENSG00000148459 ENSG00000140465 ENSG00000168522 PMC7492613__F3 JAK-STAT modulating genes in PMN-MDSCs in the circulation of CRC patients ENSG00000213928 ENSG00000138378 ENSG00000134982 ENSG00000198793 ENSG00000136997 ENSG00000159346 ENSG00000131095 PMC8698579__F1 YAP/Hippo Pathway and Cancer Immunity: It Takes Two to Tango ENSG00000177455 ENSG00000163599 ENSG00000197905 ENSG00000172936 ENSG00000074219 PMC11414529__F2 Injury induced by histone methylation disorders in diabetic nephropathy affect the major effector cells of the kidney ENSG00000108691 ENSG00000178585 ENSG00000148400 ENSG00000064393 ENSG00000108799 ENSG00000164091 ENSG00000276644 ENSG00000127528 ENSG00000168036 ENSG00000104332 ENSG00000155090 ENSG00000110693 PMC4389010__F1 The Th17 pathway and its involvement in psoriatic disease ENSG00000184995 ENSG00000149968 ENSG00000163739 ENSG00000163734 ENSG00000169429 ENSG00000124875 ENSG00000168610 ENSG00000115009 PMC6478763__F1 Mechanisms supporting BRAF inhibitor resistance in melanoma ENSG00000117020 ENSG00000157764 ENSG00000291971 ENSG00000120875 ENSG00000177606 ENSG00000175592 ENSG00000121879 ENSG00000100146 ENSG00000168610 ENSG00000155760 PMC8384742__F1 Gastrointestinal mucosal immunity and COVID-19 ENSG00000111537 ENSG00000130234 ENSG00000184012 ENSG00000049768 PMC2268740__F1 Neuroarchitecture of Aminergic Systems in the Larval Ventral Ganglion of Drosophila melanogaster ENSG00000170893 PMC3200079__F3 Homeostatic and leukemic expression of receptors, signaling proteins, and transcription factors along the B cell pathway ENSG00000177455 ENSG00000196092 ENSG00000168685 PMC6466196__F1 Schematic of IL-4 and IL-13 mediated signal transduction ENSG00000105397 ENSG00000115415 ENSG00000105639 ENSG00000168610 PMC2890032__F2 Differential vulnerability of neurons in Huntington's disease: The role of cell type-specific features PMC9316217__F9 Procyanidin B2 Alleviates Heat-Induced Oxidative Stress through the Nrf2 Pathway in Bovine Mammary Epithelial Cells ENSG00000125538 PMC11062289__F5 ENPP1 in Blood and Bone: Skeletal and Soft Tissue Diseases Induced by ENPP1 Deficiency ENSG00000118972 ENSG00000156076 ENSG00000197594 ENSG00000104332 ENSG00000177283 PMC5360281__F2 Visualization of selected miRNA targeting events on the insulin signaling pathway (from WikiPathways) ENSG00000175206 ENSG00000171105 ENSG00000111713 ENSG00000136111 ENSG00000136854 ENSG00000169047 ENSG00000142273 ENSG00000132639 ENSG00000166592 ENSG00000160691 ENSG00000179295 ENSG00000166263 ENSG00000107263 ENSG00000110395 ENSG00000163558 ENSG00000148082 ENSG00000129946 ENSG00000177606 ENSG00000197879 ENSG00000133124 ENSG00000220205 ENSG00000100219 ENSG00000152556 PMC11868719__F4 Signaling pathway of LPS-induced apoptosis ENSG00000172936 ENSG00000136869 PMC6456539__F2 Activation of autophagy process by extracellular vesicles ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC11868719__F1 Using the String database to analyze protein interactions ENSG00000143799 ENSG00000029363 ENSG00000105327 ENSG00000144824 ENSG00000163743 ENSG00000121067 ENSG00000115816 ENSG00000171791 ENSG00000150455 ENSG00000147854 ENSG00000205362 ENSG00000067369 ENSG00000196628 ENSG00000166164 ENSG00000183765 ENSG00000172216 ENSG00000125686 ENSG00000149273 ENSG00000136869 ENSG00000196498 ENSG00000116030 ENSG00000140464 ENSG00000185825 ENSG00000120837 ENSG00000142192 ENSG00000063978 ENSG00000178078 ENSG00000154589 ENSG00000144228 ENSG00000167900 ENSG00000281766 ENSG00000127445 ENSG00000108179 ENSG00000121481 ENSG00000172005 ENSG00000277258 ENSG00000258643 ENSG00000133961 ENSG00000122779 ENSG00000096717 ENSG00000175792 ENSG00000004975 ENSG00000243414 ENSG00000198382 ENSG00000002330 ENSG00000181163 ENSG00000172465 ENSG00000105254 ENSG00000112659 ENSG00000196470 ENSG00000166851 ENSG00000157557 ENSG00000150991 ENSG00000103490 ENSG00000133878 ENSG00000102226 ENSG00000197050 ENSG00000102098 ENSG00000197386 ENSG00000189403 ENSG00000185591 ENSG00000143499 ENSG00000106305 ENSG00000165471 ENSG00000046774 ENSG00000074590 ENSG00000172273 ENSG00000281306 ENSG00000005339 ENSG00000176774 ENSG00000175793 ENSG00000169682 ENSG00000005483 ENSG00000086991 ENSG00000168411 ENSG00000023902 ENSG00000124766 ENSG00000154832 ENSG00000131910 ENSG00000168040 ENSG00000086758 ENSG00000292187 ENSG00000102977 ENSG00000221823 ENSG00000188976 ENSG00000100749 ENSG00000065029 ENSG00000186716 ENSG00000165392 ENSG00000133112 ENSG00000145354 ENSG00000198911 ENSG00000198625 PMC11868719__F2 Using the String database to analyze protein interactions ENSG00000104812 ENSG00000111057 ENSG00000281324 ENSG00000187796 ENSG00000134982 ENSG00000105401 ENSG00000169710 ENSG00000115816 ENSG00000179588 ENSG00000077800 ENSG00000166508 ENSG00000170365 ENSG00000157500 ENSG00000183735 ENSG00000150907 ENSG00000136997 ENSG00000143379 ENSG00000149273 ENSG00000116030 ENSG00000126016 ENSG00000114125 ENSG00000125826 ENSG00000142192 ENSG00000143546 ENSG00000101109 ENSG00000178078 ENSG00000137275 ENSG00000285152 ENSG00000213341 ENSG00000167900 ENSG00000105568 ENSG00000007171 ENSG00000067715 ENSG00000104327 ENSG00000124216 ENSG00000069482 ENSG00000118503 ENSG00000096717 ENSG00000146648 ENSG00000104856 ENSG00000177030 ENSG00000182670 ENSG00000291971 ENSG00000198793 ENSG00000100744 ENSG00000168036 ENSG00000087586 ENSG00000145386 ENSG00000140961 ENSG00000175054 ENSG00000150991 ENSG00000088888 ENSG00000171456 ENSG00000166501 ENSG00000291837 ENSG00000284099 ENSG00000197386 ENSG00000123374 ENSG00000154310 ENSG00000118898 ENSG00000124181 ENSG00000164609 ENSG00000198286 ENSG00000100603 ENSG00000134020 ENSG00000005339 ENSG00000100906 ENSG00000109320 ENSG00000163874 ENSG00000124074 ENSG00000269335 ENSG00000198466 ENSG00000173039 ENSG00000114544 ENSG00000117899 ENSG00000127903 ENSG00000064726 ENSG00000127191 ENSG00000165233 ENSG00000165630 ENSG00000101624 ENSG00000092330 ENSG00000292204 ENSG00000079999 ENSG00000149311 ENSG00000244234 ENSG00000151746 ENSG00000151503 ENSG00000188554 ENSG00000067606 ENSG00000010810 ENSG00000106772 ENSG00000083799 ENSG00000141367 ENSG00000165617 PMC7877795__F4 Origin of tumor- and metastasis-associated macrophages in mouse models of breast cancer ENSG00000019991 ENSG00000108691 ENSG00000107562 ENSG00000163599 ENSG00000138798 ENSG00000184371 ENSG00000113520 PMC7855621__F2 Centriole and cilium biogenesis ENSG00000168014 ENSG00000188878 ENSG00000121289 ENSG00000151466 ENSG00000110274 PMC8946735__F3 Key Genes and Biochemical Networks in Various Brain Regions Affected in Alzheimer’s Disease ENSG00000124140 ENSG00000091664 ENSG00000102287 ENSG00000120251 ENSG00000087460 ENSG00000115419 ENSG00000162188 ENSG00000186469 PMC8905719__F2 RAS pathway regulation in melanoma ENSG00000198793 ENSG00000136997 ENSG00000115904 ENSG00000100485 ENSG00000196712 ENSG00000179295 PMC7438927__F6 Canonical Pathway of ‘Actin Cytoskeleton Signaling’ in IPA with AA-specific/enhanced genes in ENSG00000180210 ENSG00000038382 ENSG00000172380 ENSG00000175866 ENSG00000291971 ENSG00000134982 ENSG00000138443 ENSG00000138798 ENSG00000089159 PMC7438927__F7 Relationship between a network of DEGs and the canonical calcium signaling pathway ENSG00000113196 ENSG00000163092 ENSG00000143839 ENSG00000158764 ENSG00000128510 ENSG00000165887 ENSG00000163217 PMC7438927__F8 Networks of an unreported AA-specific/enhanced DEG (CHRNE) ENSG00000282830 ENSG00000105697 ENSG00000000971 ENSG00000108556 ENSG00000105664 ENSG00000122756 ENSG00000113296 ENSG00000101440 ENSG00000007402 ENSG00000165917 ENSG00000124818 ENSG00000116690 ENSG00000145850 ENSG00000187889 PMC3590362__F1 AGE/RAGE signaling pathway in NetSlim- This map represents the NetSlim reactions of AGE/RAGE signaling pathway in different cell types ENSG00000070831 ENSG00000291971 ENSG00000143839 ENSG00000150455 ENSG00000092820 ENSG00000164305 ENSG00000157227 ENSG00000150907 ENSG00000166501 ENSG00000185591 ENSG00000132906 ENSG00000087245 ENSG00000104365 ENSG00000171105 ENSG00000137673 ENSG00000100906 ENSG00000109320 ENSG00000162551 ENSG00000173039 ENSG00000213341 ENSG00000184481 ENSG00000168610 ENSG00000007171 ENSG00000244038 ENSG00000067606 ENSG00000177606 ENSG00000172936 ENSG00000100985 ENSG00000038945 ENSG00000146648 PMC4972490__F1 BRCA1 and BRCA2: different roles in a common pathway of genome protection ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000136492 ENSG00000083093 ENSG00000051180 ENSG00000112130 ENSG00000139618 PMC6335777__F2 Ketamine on the glutamatergic synapse ENSG00000198793 ENSG00000284161 PMC2675030__F3 Steps in the generation of Th17 cells ENSG00000162594 ENSG00000103522 ENSG00000168610 ENSG00000069667 PMC9218220__F3 Reactive Oxygen Species and Metabolism in Leukemia: A Dangerous Liaison ENSG00000122966 ENSG00000137857 ENSG00000005882 ENSG00000140279 ENSG00000086991 ENSG00000074771 PMC3023199__F3 PPARG ligand treatments increase expression of mitochondria-associated metabolic pathways in adipose tissue ENSG00000175198 ENSG00000113790 ENSG00000105552 PMC4862319__F1 Simplified schematic of signaling junctions that integrate the recognition of pathogen, host or environmentally derived DAMPs and dAMPs by their cognate receptors ENSG00000162711 ENSG00000163568 ENSG00000163565 ENSG00000091592 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000125538 ENSG00000189403 ENSG00000136869 ENSG00000172936 ENSG00000164342 PMC3023199__F4 Dysregulated expression of fatty acid and cholesterol synthesis genes in liver is reversed by PPARG ligand treatments ENSG00000110921 ENSG00000104549 ENSG00000127948 ENSG00000026103 PMC5727914__F5 Interferon signaling in HPV-containing keratinocytes ENSG00000159128 ENSG00000213928 ENSG00000027697 ENSG00000125347 ENSG00000276561 ENSG00000142166 ENSG00000183735 ENSG00000111537 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000147896 ENSG00000146648 PMC3142627__F1 Procession to Pediatric Bacteremia and Sepsis: A Series of Covert Operations and Failures in Diplomacy ENSG00000226275 ENSG00000167207 ENSG00000134982 ENSG00000203710 ENSG00000106100 PMC4394435__F1 The ubiquitination pathway ENSG00000145604 ENSG00000033178 ENSG00000069869 ENSG00000131508 ENSG00000175104 ENSG00000119048 PMC4394435__F2 The SUMOylation pathway ENSG00000142230 ENSG00000153201 ENSG00000062485 PMC8894020__F5 Quantitative Proteomics Analysis Expands the Roles of Lysine Beta-Hydroxybutyrylation Pathway in Response to Environmental Beta-Hydroxybutyrate ENSG00000280831 ENSG00000100811 ENSG00000155506 ENSG00000277909 ENSG00000142798 ENSG00000162244 ENSG00000072274 ENSG00000153201 ENSG00000177556 ENSG00000079134 ENSG00000169710 ENSG00000058673 ENSG00000179295 ENSG00000162385 ENSG00000102189 ENSG00000166233 ENSG00000138035 ENSG00000118363 ENSG00000172534 ENSG00000168214 ENSG00000285121 ENSG00000095002 ENSG00000087448 ENSG00000136068 PMC4424773__F2 Proposed signaling pathway for fat taste ENSG00000135218 ENSG00000167323 ENSG00000070985 PMC7367654__F7 Triptolide-induced apoptosis in non-small cell lung cancer via a novel miR204-5p/Caveolin-1/Akt-mediated pathway ENSG00000096717 ENSG00000142082 PMC8879981__F1 Unravelling Formaldehyde Metabolism in Bacteria: Road towards Synthetic Methylotrophy ENSG00000178860 ENSG00000291507 ENSG00000171444 PMC5757547__F2 Glucose-lipid crosstalk in diabetic kidney disease ENSG00000042832 ENSG00000198793 ENSG00000096717 ENSG00000026103 PMC3321211__F4 Apoptotic cascade ENSG00000132906 ENSG00000006712 ENSG00000164305 PMC8033373__F4 Biomarkers and key pathways in atrial fibrillation associated with mitral valve disease identified by multi-omics study ENSG00000100979 PMC9689226__F8 Overcoming Anxiety Disorder by Probiotic Lactiplantibacillus plantarum LZU-J-TSL6 through Regulating Intestinal Homeostasis ENSG00000159224 ENSG00000171388 ENSG00000161610 ENSG00000170893 ENSG00000198670 ENSG00000152266 ENSG00000174417 ENSG00000146469 ENSG00000248329 ENSG00000102539 ENSG00000181408 ENSG00000075073 ENSG00000157005 ENSG00000274473 ENSG00000169836 ENSG00000183395 ENSG00000139574 ENSG00000096395 ENSG00000069482 ENSG00000291972 ENSG00000004948 ENSG00000166863 ENSG00000115263 ENSG00000165409 ENSG00000196689 PMC4427070__F12 Summary of the three-way interaction among AMPK, SIRT1, and eNOS.Notes: AMPK and SIRT1 exhibit a bidirectional interaction in response to cellular energy status and regulate lipid metabolism and inflammatory status ENSG00000096717 ENSG00000026103 PMC6767293__F4 Effect of corilagin on the TGFB signaling pathway in ovarian cancer ENSG00000132646 PMC6071523__F8 Schematic illustration of the crosstalk between CAFs and cancer cells in the tumor microenvironment ENSG00000168036 PMC4118286__F1 Major physiological functions of the endoplasmic reticulum and their perturbations cause ER stress and activate the unfolded protein response ENSG00000128272 ENSG00000144895 PMC12127259__F2 Photo shows the signaling pathways in which each long non-coding factor interacts through different MIR signaling pathways (By Figdraw ENSG00000292354 ENSG00000168779 PMC6767293__F3 The effect of corilagin on the Notch-mTOR signaling pathway in cholangiocarcinoma ENSG00000283780 ENSG00000148400 ENSG00000198793 ENSG00000114315 PMC4061161__F1 The potential roles of hepatocyte growth factor (HGF)-MET pathway inhibitors in cancer treatment ENSG00000019991 ENSG00000291971 ENSG00000198793 ENSG00000163914 ENSG00000099942 ENSG00000168610 PMC12127259__F3 Photo shows the signaling pathways in which each long non-coding factor interacts through different MIR signaling pathways (By Figdraw ENSG00000112715 PMC12127259__F4 Photo shows the signaling pathways in which each long non-coding factor interacts through the Hedgehog signaling pathway (By Figdraw ENSG00000128602 PMC3035824__F5 Mapk signaling pathway from KEGG ENSG00000198517 ENSG00000146648 PMC4287242__F5 Signaling pathways associated with capacitation-related proteins ENSG00000163558 ENSG00000167468 ENSG00000185591 ENSG00000104388 ENSG00000117475 ENSG00000007171 ENSG00000291368 ENSG00000158106 PMC3955735__F5 Glucose and glutamine metabolism is altered by oncogenic K-Ras ENSG00000125166 ENSG00000065833 ENSG00000197713 ENSG00000074800 ENSG00000198380 ENSG00000153574 ENSG00000115419 ENSG00000159399 PMC6202151__F7 Schematic depiction of proposal mechanism by which AF confers anticancer actions in TamR breast cancer cells ENSG00000291971 ENSG00000091409 PMC5828949__F2 The role of renal dipeptidyl peptidase-4 in kidney disease: renal effects of dipeptidyl peptidase-4 inhibitors with a focus on linagliptin ENSG00000197635 ENSG00000077782 PMC8507250__F8 Nanoselenium transformation and inhibition of cadmium accumulation by regulating the lignin biosynthetic pathway and plant hormone signal transduction in pepper plants ENSG00000084774 PMC9267745__F6 VEGFA, KRAS, and NFE2L2 Oncogenes by MicroRNAs in Head and Neck Cancer ENSG00000116044 ENSG00000198793 ENSG00000112715 PMC9414852__F8 MOBT Alleviates Pulmonary Fibrosis through an lncITPF–hnRNP-l-Complex-Mediated Signaling Pathway ENSG00000248905 ENSG00000081189 PMC3365812__F3 Hh signaling pathway and their inhibitors ENSG00000136997 ENSG00000128602 PMC11502918__F5 An intricate relationship between ER stress and lncRNAs: bidirectional relationship between ER stress and lncRNAs in the context of the UPR pathway ENSG00000128272 ENSG00000100219 PMC6052836__F1 The regulation of the anti-viral signaling pathway ENSG00000127445 ENSG00000239732 ENSG00000164430 ENSG00000163568 ENSG00000163565 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC11502918__F6 LncRNAs in ER stress-driven HCC progression ENSG00000128272 ENSG00000002330 PMC7830727__F1 Ferroptotic cell death pathway ENSG00000167468 ENSG00000167996 PMC11502918__F4 Diverse lncRNA-medicated signaling pathways targeting different hallmarks of cancer (lncRNAs written in black and red color represent oncogenes and tumor suppressors, respectively) ENSG00000198793 ENSG00000124766 ENSG00000253352 ENSG00000160294 PMC7830727__F2 Necroptotic cell death pathway ENSG00000102871 ENSG00000056558 ENSG00000168040 ENSG00000168404 ENSG00000127191 PMC11502918__F1 Various stress at ER levels causes the induction of UPR pathway ENSG00000128272 ENSG00000100219 PMC7830727__F3 Canonical, non-canonical, and caspase-3-dependent pyroptotic cell death pathway ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000091592 ENSG00000091106 PMC8771506__F6 POU4F3 Acts as a Tumor Suppressor in Lung Adenocarcinoma via the Endoplasmic Reticulum Stress Signaling Pathway ENSG00000091010 ENSG00000128272 ENSG00000144895 PMC3936289__F4 Major crosstalks between the PI3K and the MAPK cascades ENSG00000169047 ENSG00000198793 ENSG00000136997 ENSG00000164327 PMC11205484__F2 Biosynthetic Pathways of Protectins and Maresins in Macrophages and MaR-2 in Brown Adipose Tissue Activation ENSG00000100473 ENSG00000133067 ENSG00000121807 PMC8584803__F1 Biochemical Markers for the Diagnosis of Mitochondrial Fatty Acid Oxidation Diseases ENSG00000157184 ENSG00000166278 PMC6189190__F5 The thiosemicarbazone Me2NNMe2 induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition ENSG00000170458 ENSG00000102871 ENSG00000177606 ENSG00000130159 ENSG00000175104 ENSG00000127191 ENSG00000196712 ENSG00000026103 PMC7887571__F1 a) Schematic illustration of the HCJSP prodrug nanoparticle prepared via the host–guest interaction between HA‐CD and AD‐SS‐JQ1 and AD‐SS‐PPa ENSG00000141867 ENSG00000159399 PMC5804041__F2 PPARA-RXR signaling pathway ENSG00000116254 ENSG00000169291 ENSG00000175745 ENSG00000169047 ENSG00000177606 ENSG00000169710 ENSG00000131910 ENSG00000132170 PMC7399876__F1 Tax activation of canonical and noncanonical NFKB signaling ENSG00000182985 ENSG00000083799 ENSG00000120913 ENSG00000175104 ENSG00000112130 PMC6130939__F11 GRK2 mediates TCR-induced transactivation of CXCR4 and TCR–CXCR4 complex formation required for PI3KG/PREX1 signaling and robust T cell cytokine secretion ENSG00000291971 ENSG00000124126 ENSG00000121966 PMC4669719__F8 Schematic diagram of the NRG1-ERBB4-NRG1 autocrine pathway ENSG00000178568 PMC5509685__F1 Simplified sphingolipid metabolic pathway ENSG00000063176 ENSG00000166224 ENSG00000115419 PMC5400657__F1 Long non-coding RNAs: a rising biotarget in colorectal cancer ENSG00000169554 ENSG00000044115 ENSG00000136997 ENSG00000026508 ENSG00000171791 ENSG00000178568 PMC8488354__F4 Cholinergic Receptor Modulation as a Target for Preventing Dementia in Parkinson’s Disease ENSG00000291507 ENSG00000168610 PMC8040296__F7 PI3K-AKT Signaling Pathway ENSG00000041982 ENSG00000099985 ENSG00000169047 ENSG00000136997 PMC8040296__F8 Protein-protein interaction in the PI3K-AKT signalling pathway and ECM-receptor interactions ENSG00000118972 ENSG00000114450 ENSG00000134460 ENSG00000005961 ENSG00000110799 ENSG00000181104 ENSG00000163064 ENSG00000134871 ENSG00000112715 ENSG00000169231 ENSG00000137801 ENSG00000145431 ENSG00000117020 ENSG00000041982 ENSG00000145623 ENSG00000186340 ENSG00000113296 ENSG00000134853 ENSG00000118515 ENSG00000108821 PMC8488354__F3 Cholinergic Receptor Modulation as a Target for Preventing Dementia in Parkinson’s Disease ENSG00000142192 ENSG00000168036 PMC4961262__F1 The SDF1/CXCR4 signaling pathway ENSG00000164458 ENSG00000164690 ENSG00000077782 PMC3694992__F1 Neuroimmune Signaling: A Key Component of Alcohol Abuse ENSG00000170458 ENSG00000189403 ENSG00000136869 ENSG00000150455 PMC3798191__F5 The relationships between the RA, FGF and Notch pathway in Xenopus PSM ENSG00000168214 ENSG00000149187 PMC5278230__F7 Proposed mechanism underlying HSYA-SDT-induced autophagy and inflammation inhibition in THP-1 macrophages ENSG00000090402 ENSG00000198793 ENSG00000057663 PMC8449655__F1 De novo biosynthesis of garbanzol and fustin in Streptomyces albus based on a potential flavanone 3‐hydroxylase with 2‐hydroxylase side activity ENSG00000117525 ENSG00000074800 PMC10486718__F1 Schematically representing the signal transduction and biological activities induced by androgen in ER-positive breast cancer cells ENSG00000291971 ENSG00000138798 ENSG00000118515 PMC4461014__F5 Dual function of genes ENSG00000100234 ENSG00000087245 ENSG00000134982 ENSG00000168036 ENSG00000112715 ENSG00000137801 ENSG00000100592 ENSG00000095739 ENSG00000147869 ENSG00000167941 ENSG00000136997 ENSG00000136869 ENSG00000100985 PMC10486718__F2 Schematically representing the signal transduction and biological activities induced by androgen in ER-negative breast cancer cells ENSG00000291971 ENSG00000149269 ENSG00000138798 ENSG00000118515 ENSG00000137076 PMC10486718__F3 Diagram illustrating the androgen-mediated signal transduction via integrins and the resulting biological activities ENSG00000198793 PMC9354823__F1 Connections between metabolism and epigenetics: mechanisms and novel anti-cancer strategy ENSG00000131473 ENSG00000147162 ENSG00000198408 ENSG00000115419 PMC6603400__F1 Diagram of ellagic acid target proteins from the DrugBank database ENSG00000095585 ENSG00000038382 ENSG00000168748 ENSG00000164879 ENSG00000166501 ENSG00000104549 ENSG00000164327 ENSG00000101266 ENSG00000141564 ENSG00000074410 ENSG00000167434 PMC10874560__F3 Representative bacterial-origin immunostimulants signaling pathway ENSG00000239732 ENSG00000117400 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000091106 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC8291481__F4 Integration of Mass Spectrometry Imaging and Machine Learning Visualizes Region-Specific Age-Induced and Drug-Target Metabolic Perturbations in the Brain ENSG00000173599 ENSG00000087085 ENSG00000016391 PMC6878604__F1 FGFR pathway.FGFRs dimerize upon ligand building and trigger a downstream cascade of signaling pathways PMC3365812__F1 Wnt/Beta-Catenin signaling pathway and their inhibitors ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000136997 PMC2270852__F5 Schematic of signaling pathways in PDAC ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC5819921__F4 Bioinformatics prediction of genes interacting with RAC1 using Ingenuity Pathway Analysis ENSG00000162552 ENSG00000053747 ENSG00000002330 ENSG00000089685 ENSG00000111837 ENSG00000064012 PMC9437975__F7 Integrative analyses of mRNA and microRNA expression profiles reveal the innate immune mechanism for the resistance to Vibrio parahaemolyticus infection in Epinephelus coioides ENSG00000108691 ENSG00000000971 ENSG00000112378 ENSG00000171791 ENSG00000142224 ENSG00000062485 PMC6250852__F1 Oxidative stress and activation of Cerebrovascular Endothelial Cells ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000162692 PMC3865646__F2 Apoptosis by hypothermia ENSG00000132906 ENSG00000064012 ENSG00000164305 PMC8905719__F5 RAS pathway regulation in melanoma ENSG00000115904 ENSG00000179295 PMC4461014__F1 Dual function of TAK1 ENSG00000157625 ENSG00000175104 PMC3132106__F1 Summary of the extracellular interactions between Wnts, Wnt receptors and Wnt regulatory proteins ENSG00000030304 ENSG00000168036 PMC3176435__F2 Alternative miRNA biogenesis pathways and the interpretation of core miRNA pathway mutants ENSG00000134698 PMC10742473__F4 Canonical and alternative signaling pathways in B-cells ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000198793 ENSG00000197943 ENSG00000010671 PMC7494657__F4 Networks under “Pathways in Cancer” that were enriched in Masquelet bone ENSG00000074181 ENSG00000188064 ENSG00000067606 ENSG00000111186 ENSG00000136160 ENSG00000002745 ENSG00000168398 ENSG00000151617 ENSG00000127588 ENSG00000128602 ENSG00000276799 ENSG00000069966 PMC10150004__F1 Infection routes, invasion mechanisms, and drug inhibition pathways of human coronaviruses on the nervous system ENSG00000169245 ENSG00000108691 ENSG00000197635 ENSG00000130234 ENSG00000138755 ENSG00000184012 ENSG00000277943 PMC2769198__F2 Smad4: gatekeeper gene in head and neck squamous cell carcinoma ENSG00000019991 ENSG00000138798 PMC7658242__F8 IL-22 ameliorates LPS-induced acute liver injury by autophagy activation through ATF4-ATG7 signaling ENSG00000128272 PMC3201689__F1 Diagram illustrating the DNA base excision repair (BER) pathway ENSG00000105486 PMC6058973__F2 Regulation of GPCR signaling ENSG00000111537 ENSG00000115415 ENSG00000100219 PMC5655209__F8 Glypican-3 induces oncogenicity by preventing IGF-1R degradation, a process that can be blocked by Grb10 ENSG00000106070 PMC2427358__F8 Summary of GRTH impact in apoptotic pathways in germ cells ENSG00000002330 ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC6314240__F2 TGFB signaling as well as the role of TGFB signaling pathway in cancer onset and progression ENSG00000198793 ENSG00000163914 PMC6617169__F2 Signaling pathways involved in the protective effects of tea bioactive compounds against cardiovascular diseases ENSG00000196689 PMC2424295__F2 Feedback loops in NFKB signaling ENSG00000172936 ENSG00000136869 PMC3775269__F6 CTLA4Ig inhibits effector T cells through regulatory T cells and TGFB ENSG00000111537 ENSG00000134982 PMC4373383__F1 Network of HMGA regulatory mechanisms in human carcinomas ENSG00000221914 PMC5310720__F1 PD genes and autophagy-endolysosomal pathway(s) ENSG00000292221 ENSG00000100225 ENSG00000132718 ENSG00000158828 ENSG00000069329 PMC6854084__F6 Proposed model for apoptosis suppression via R-Ras pathway by RasGRP2 ENSG00000159399 PMC8966724__F2 Mitochondrial DNA Release Contributes to Intestinal Ischemia/Reperfusion Injury ENSG00000162711 ENSG00000183735 ENSG00000239732 ENSG00000164430 PMC8196476__F3 Innate immunity, inflammation activation and heat-shock protein in COVID-19 pathogenesis ENSG00000162711 ENSG00000150782 ENSG00000130234 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC11050413__F10 Mechanistic map illustrates the role of NDUFA6-DT as a sponge for miR-455-3p in gliomas, disrupting its ability to suppress YWHAH/YWHAG expression ENSG00000002330 ENSG00000170027 ENSG00000101224 PMC9605422__F9 Research Progress on Fungal Sesterterpenoids Biosynthesis ENSG00000197429 PMC3196210__F2 Relationships of different neurons in the striatum and neurotransmitter signaling involved in interval timing ENSG00000196531 ENSG00000145321 PMC2647704__F5 Schematic of selenoprotein synthesis ENSG00000155926 ENSG00000179988 PMC9688625__F7 Targeting Wnt/Beta-Catenin Signaling Exacerbates Ferroptosis and Increases the Efficacy of Melanoma Immunotherapy via the Regulation of MITF ENSG00000111537 ENSG00000167468 ENSG00000168036 PMC8233150__F8 A20/Nrdp1 interaction alters the inflammatory signaling profile by mediating K48- and K63-linked polyubiquitination of effectors MyD88 and TBK1 ENSG00000183735 ENSG00000172936 ENSG00000175104 PMC3180925__F1 Wnts signal through a “canonical” pathway involving Beta-catenin mediated transcriptional regulation (at left) and through “non-canonical” pathways involving calcium and Rac/JNK-mediated signaling (at right) ENSG00000134982 ENSG00000168036 ENSG00000026103 PMC11668870__F2 TRIM14 plays a double-edged role in cancer ENSG00000004975 ENSG00000183735 ENSG00000106785 ENSG00000164430 ENSG00000198793 ENSG00000170430 ENSG00000137310 ENSG00000168610 PMC11668870__F3 Emerging discoveries on the role of TRIM14: from diseases to immune regulation ENSG00000162711 ENSG00000106785 PMC11724432__F4 Mitochondrial Apoptosis and Inflammation ENSG00000162711 ENSG00000164430 ENSG00000120868 PMC7407293__F1 Nuclear factor-kappaB (NF-kappaB) signaling pathway ENSG00000104856 ENSG00000186716 PMC11668870__F4 Expression of TRIM14 is upregulated in response to inflammatory stimuli, subsequently enhancing the expression of pro-inflammatory factors ENSG00000104856 ENSG00000185515 ENSG00000106785 ENSG00000123240 ENSG00000168036 ENSG00000136869 ENSG00000186280 ENSG00000101695 ENSG00000101557 PMC11668870__F5 Emerging discoveries on the role of TRIM14: from diseases to immune regulation ENSG00000106785 ENSG00000164430 ENSG00000088888 ENSG00000115415 ENSG00000276561 ENSG00000101557 PMC7481463__F6 Biomarker metabolites network based on intelligent pathway analysis use IPA analysis ENSG00000089041 ENSG00000132478 PMC9273868__F5 Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform ENSG00000103266 ENSG00000170745 ENSG00000182674 ENSG00000081237 ENSG00000165280 ENSG00000127191 ENSG00000274286 PMC7046484__F8 Schematic illustration summarizes the epiregulin promoted trophoblast cells invasion by targeting poFUT1 and O‐fucosylation on uPA, which stimulated PI3K/Akt signalling pathway and MMP 9 activity ENSG00000170558 ENSG00000101346 ENSG00000100985 ENSG00000146648 ENSG00000122194 PMC8674574__F2 Programmed Cell Death of Macrophages, Endothelial Cells, and Tubular Epithelial Cells in Sepsis-AKI ENSG00000278718 ENSG00000035115 ENSG00000162711 ENSG00000125538 ENSG00000086991 ENSG00000136869 ENSG00000168404 ENSG00000285379 PMC8557391__F2 Nrf2/Keap1/ARE signaling: Towards specific regulation ENSG00000178573 ENSG00000079999 PMC7961726__F2 Representation molecular mechanisms underlying the tumoral properties of glioma cells ENSG00000170430 ENSG00000146648 ENSG00000128191 PMC11594620__F1 Metabolic pathway of complex sphingolipids in budding yeast Saccharomyces cerevisiae ENSG00000228278 ENSG00000229314 PMC3784667__F2 Intracellular cycling of MUC1MUC1 is phosphorylated by EGFR and other receptor tyrosine kinases ENSG00000291971 ENSG00000146648 PMC3912412__F6 Interaction of CLL cells and the lymph node microenvironment ENSG00000125740 ENSG00000072694 ENSG00000118503 ENSG00000120875 ENSG00000130522 ENSG00000125538 ENSG00000166278 ENSG00000112149 ENSG00000158050 PMC12015243__F6 EPHA5 promotes cell proliferation and inhibits apoptosis in Follicular Thyroid Cancer via the STAT3 signaling pathway ENSG00000136997 ENSG00000168610 PMC6315659__F2 Regulation of the Hippo/YAP signaling pathway in malignant pleural mesothelioma (MPM) and non-small cell lung cancer (NSCLC) ENSG00000186575 ENSG00000138798 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC8396181__F2 Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects ENSG00000010361 ENSG00000092148 PMC6160868__F1 Wnt/Beta-catenin driven mevalonate metabolism promotes EMT ENSG00000131473 ENSG00000160752 ENSG00000110921 ENSG00000112972 ENSG00000197429 ENSG00000113161 ENSG00000168036 ENSG00000167508 PMC7695367__F7 The proposed mechanism of radiation-induced tumor repopulation in NSCLC ENSG00000188486 ENSG00000149311 ENSG00000164305 PMC7014214__F2 Anticancer mechanisms of phytochemicals on gastric cancer ENSG00000175054 ENSG00000087245 ENSG00000128272 ENSG00000148400 ENSG00000145782 PMC2597223__F1 Pathways of apoptosis ENSG00000198576 ENSG00000168040 PMC11717529__F7 Mechanism of action of hsa_circ_0109623 and hsa-miR-146b-3p and their downstream target gene SORT1 in the pathogenesis of AIH ENSG00000138378 ENSG00000115415 ENSG00000134243 PMC7977493__F8 Stiffness of Nanoparticulate Mineralized Collagen Scaffolds Triggers Osteogenesis via Mechanotransduction and Canonical Wnt Signaling ENSG00000170365 ENSG00000134982 ENSG00000163914 PMC3765909__F2 Mechanism of blockade of the Wnt signalling pathway by osteocytes ENSG00000281324 ENSG00000162337 PMC2974212__F3 Critical growth factors and signalling pathways controlling human trophoblast invasion ENSG00000019991 ENSG00000138798 ENSG00000198793 ENSG00000163914 PMC7294938__F3 Mechanotransduction and pathways regulating cytoskeleton during metastasis ENSG00000154864 ENSG00000198793 ENSG00000103335 PMC7083089__F4 Secondary structures at CFSs can impede replication, resulting in fork stalling and cleavage to cause fragility ENSG00000175054 ENSG00000188827 PMC6711159__F1 Closer Look at Pyroptosis ENSG00000162711 ENSG00000150782 ENSG00000143546 ENSG00000125538 ENSG00000168036 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC6020732__F2 AhR in breast cancer and the role of dietary compounds ENSG00000012048 ENSG00000262635 ENSG00000171759 ENSG00000106546 PMC4486131__F5 OFE treatment counteracted TGFB1-activated SMAD pathways ENSG00000140937 ENSG00000170558 PMC8345973__F1 Gasotransmitters for the Therapeutic Prevention of Hypertension and Kidney Disease PMC7412635__F7 The dichotomous effects of VCD on follicular development ENSG00000164404 ENSG00000106410 PMC8942302__F3 STAT3 pathway in cancers: Past, present, and future ENSG00000120833 ENSG00000239732 ENSG00000099985 ENSG00000291971 ENSG00000138798 ENSG00000136869 ENSG00000168610 ENSG00000146648 PMC4022607__F1 Angiomotin phosphorylation in the Hippo pathway during preimplantation mouse development ENSG00000121058 ENSG00000197905 ENSG00000166025 ENSG00000007866 ENSG00000150457 ENSG00000114019 ENSG00000131023 ENSG00000074219 PMC4453519__F3 Activation of the cytokine-cytokine receptor interaction pathway in incubations with BL21 or W3110 ENSG00000122025 ENSG00000118503 ENSG00000164400 ENSG00000162692 ENSG00000135503 ENSG00000112486 PMC4987729__F2 Processing of engulfed dying cells requires LC3-associated phagocytosis (LAP) and promotes an anti-inflammatory response ENSG00000198382 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC11704872__F4 The IGF-1 Signaling Pathway in Mitophagy ENSG00000106459 PMC11279976__F2 Common metabolic pathways of NAD+ and NMN ENSG00000105835 ENSG00000123572 ENSG00000278488 ENSG00000157064 ENSG00000173614 PMC11704872__F3 Inhibition of autophagy by the IGF-1 signaling pathway ENSG00000177169 ENSG00000002330 ENSG00000083290 ENSG00000169047 ENSG00000155792 ENSG00000140443 PMC2754696__F1 CIE and CDE pathways showing lipid content and regulatory molecules ENSG00000013016 ENSG00000070831 ENSG00000291971 ENSG00000165527 PMC8393605__F2 Exploring the Interplay of Telomerase Reverse Transcriptase and Beta-Catenin in Hepatocellular Carcinoma ENSG00000134982 ENSG00000164362 ENSG00000168036 ENSG00000136826 ENSG00000196628 PMC10218028__F2 SNPs affecting NET formation ENSG00000137747 ENSG00000118503 ENSG00000162849 ENSG00000005381 PMC9151343__F1 Metabolic engineering of Vibrio natriegens for anaerobic succinate production ENSG00000122966 ENSG00000172005 ENSG00000150787 ENSG00000062485 PMC12080488__F4 Figure illustrates the JAK/STAT signaling pathway and its role in cancer progression, highlighting its influence on tumor invasion, progression, autophagy, and apoptosis ENSG00000122691 ENSG00000168610 PMC6529540__F3 Omics analysis discovered high-confidence networks involved in AD ENSG00000142192 ENSG00000150991 ENSG00000168036 PMC10962118__F9 Mechanistic map of PELI1 ubiquitination of RPS3 activating the PI3K/AKT/GSK3B signaling pathway, promoting p53 degradation, and thus facilitating progression in PC ENSG00000149273 PMC6359191__F1 Cartoon representing the osteolytic and osteosclerotic vicious cycles ENSG00000154342 ENSG00000167941 ENSG00000138798 ENSG00000125084 PMC10851593__F4 Lignin synthesis pathway map ENSG00000084774 PMC6348604__F1 Apoptotic signaling pathway ENSG00000002330 ENSG00000171791 PMC5542661__F1 Patients experiencing statin-induced myalgia exhibit a unique program of skeletal muscle gene expression following statin re-challenge ENSG00000226479 ENSG00000138772 ENSG00000116667 ENSG00000167476 ENSG00000114737 ENSG00000023287 ENSG00000132478 ENSG00000196470 ENSG00000162999 ENSG00000127334 ENSG00000159788 ENSG00000185344 ENSG00000197381 ENSG00000152556 PMC5041942__F2 Dissecting dysfunctional crosstalk pathways regulated by miRNAs during glioma progression ENSG00000236826 ENSG00000112715 PMC7505161__F3 Toll-like receptor 4 (TLR4) activation in the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection ENSG00000130234 ENSG00000136869 PMC3328281__F1 Molecular changes of serous carcinogenesis ENSG00000012048 ENSG00000128512 ENSG00000157764 ENSG00000121879 ENSG00000139687 PMC9501394__F2 Pharmacological Effects of Houttuynia cordata Thunb (H. cordata): A Comprehensive Review ENSG00000171791 ENSG00000079999 PMC11727388__F4 Aberrant tumorigenic ECM modulates several intracellular signaling pathways involved in tumor development and progression ENSG00000126016 ENSG00000186575 ENSG00000291971 ENSG00000134982 ENSG00000198793 ENSG00000163914 ENSG00000026508 ENSG00000103335 PMC2224766__F3 Proposed metabolic pathway for PSI-6130 ENSG00000158825 ENSG00000129187 PMC2825553__F1 Interplay of cellular stress signals with apoptosis pathways ENSG00000168040 PMC8253836__F1 Consolidated bioprocessing for bioethanol production by metabolically engineered Bacillus subtilis strains ENSG00000144063 ENSG00000150787 PMC9584705__F8 Methylation-Mediated Silencing of RBP7 Promotes Breast Cancer Progression through PPAR and PI3K/AKT Pathway ENSG00000162444 PMC2739091__F8 Schematics of the effect IL-1B on the alveolar capillary barrier ENSG00000125538 ENSG00000168036 PMC7016983__F2 Metformin (MET) AMPK dependent signaling ENSG00000177169 ENSG00000198793 ENSG00000112561 ENSG00000140464 ENSG00000084774 PMC7216182__F6A BST Stimulation Induces Atrophy and Changes in Aerobic Energy Metabolism in Rat Skeletal Muscles—The Biphasic Action of Endogenous Glucocorticoids ENSG00000176387 PMC9457820__F6 Small Molecule Inhibitors for Hepatocellular Carcinoma: Advances and Challenges ENSG00000134982 ENSG00000168036 PMC2631033__F1 Tumor necrosis factor and cancer, buddies or foes? ENSG00000132906 ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000164305 PMC9657218__F4 Contribution of Microhomology to Genome Instability: Connection between DNA Repair and Replication Stress ENSG00000143799 ENSG00000149311 ENSG00000138346 ENSG00000051180 PMC6498051__F7 IFNG pathway associated with differentially expressed genes between SRHIC and WRHIC purified CD8 T cells ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000004455 ENSG00000125347 PMC9674404__F3 Signaling condensates in the B cell receptor pathway ENSG00000186716 ENSG00000121058 PMC8699740__F2 Integrin AE(CD103)B7 in Epithelial Cancer ENSG00000083457 ENSG00000020633 ENSG00000124181 PMC7069516__F14 Interrupting cyclic dinucleotide-cGAS–STING axis with small molecules ENSG00000183735 ENSG00000164430 PMC6426138__F6 Ciliary TGFB/BMP signalling ENSG00000170365 ENSG00000198742 ENSG00000100629 ENSG00000128602 PMC8942302__F6 STAT3 pathway in cancers: Past, present, and future ENSG00000291971 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC3423475__F9 Animal oral and veg1 ectodermal GRN for sea urchin embryogenesis ENSG00000133937 ENSG00000156574 PMC4743530__F3 Mechanical Forces Reshape Differentiation Cues That Guide Cardiomyogenesis ENSG00000166823 ENSG00000134982 ENSG00000168036 PMC11050262__F14 Cytotoxic effect of cisplatin on the HT-29 cell line based on gene expression and pathway analysis ENSG00000002330 ENSG00000120868 PMC8166571__F1 Diet Regulation of Long-Chain PUFA Synthesis: Role of Macronutrients, Micronutrients, and Polyphenols on Δ-5/Δ-6 Desaturases and Elongases 2/5 ENSG00000134824 ENSG00000149485 ENSG00000197977 PMC9619038__F1 Editorial: Sirtuins and brain homeostasis ENSG00000162711 ENSG00000096717 ENSG00000142082 ENSG00000283100 PMC4997943__F2 CEACAM6 Signaling Pathway ENSG00000291971 ENSG00000086548 PMC8016635__F3 Impact of PERK signalling activation on osteoclastogenesis ENSG00000128272 ENSG00000144895 ENSG00000131196 PMC8016635__F1 Brief diagram of the PERK signalling pathway ENSG00000171105 ENSG00000128272 ENSG00000144895 ENSG00000150907 ENSG00000198793 ENSG00000079999 PMC11580516__F3 Key Mechanisms of Metabolic and Immune Modulation in the Tumor Microenvironment ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8016635__F2 Downstream changes caused by activation of PERK on osteoblastogenesis ENSG00000162733 ENSG00000128272 ENSG00000144895 ENSG00000150907 ENSG00000155011 ENSG00000168036 ENSG00000131196 PMC3999173__F2 Lymphotoxin organizes contributions to host defense and metabolic illness from innate lymphoid cells ENSG00000162594 ENSG00000226275 ENSG00000137077 ENSG00000172936 ENSG00000111321 ENSG00000106546 PMC11580516__F4 Molecular Mechanisms of Breast Cancer Metastasis, Drug Resistance, and Target Organ Selection ENSG00000087245 ENSG00000108691 ENSG00000107562 ENSG00000137033 ENSG00000125538 ENSG00000113520 ENSG00000145777 ENSG00000100985 ENSG00000166090 PMC6039966__F3 The AhR genomic pathway ENSG00000291971 ENSG00000106546 PMC7599061__F1 Schematic process of the SARS-CoV-2’s internalization, proliferation in the cell, and influence on RAS ENSG00000130234 ENSG00000184012 PMC8835793__F3 Predominant Role of mTOR Signaling in Skin Diseases with Therapeutic Potential ENSG00000168036 ENSG00000167965 ENSG00000140443 PMC4507501__F1 New targets in cancer cell metabolism are shown PMC4392459__GA Propane synthesis derived from a fermentative butanol pathway is enabled by metabolic engineering ENSG00000106546 PMC8466366__F1 Fungal Cell Wall Proteins and Signaling Pathways Form a Cytoprotective Network to Combat Stresses ENSG00000070831 ENSG00000101871 ENSG00000062485 PMC2075035__F4 Scheme of the LNB/GNB pathway in B ENSG00000069482 PMC5470086__F1 Intestinal FXR and TGR5 signaling in metabolic regulation ENSG00000160867 ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC2075035__F2 Scheme of the Leloir pathway PMC7829888__F4 Alternative growth factor driven signaling pathways after androgen blockade ENSG00000291971 ENSG00000138798 ENSG00000168610 PMC6516512__F1 Major steps in the catabolism of BCAA ENSG00000060982 ENSG00000169710 ENSG00000103507 ENSG00000105552 ENSG00000163644 PMC12034555__F1 Biogenesis of exosomes depends on two pathways ESCRT dependent and ESCRT-independent ENSG00000106683 ENSG00000115561 ENSG00000136100 ENSG00000168461 ENSG00000189375 ENSG00000074319 ENSG00000135404 ENSG00000067900 ENSG00000146648 PMC1860592__F2 Biologic therapies: what and when? ENSG00000163599 PMC12034555__F2 This figure shows the role of EV-associated proteins in TNBC progression through various molecular interactions: 1 ENSG00000148400 ENSG00000272398 ENSG00000026508 ENSG00000137845 ENSG00000146648 PMC7565467__F2 Key components of the Ca2+signalling machinery in the control of cell proliferation and the cell cycle ENSG00000167323 ENSG00000293604 ENSG00000177606 ENSG00000136997 ENSG00000198576 ENSG00000139687 PMC8809092__F7 Suppression of canonical TGFB signaling enables GATA4 to interact with H3K27me3 demethylase JMJD3 to promote cardiomyogenesis ENSG00000151376 ENSG00000285109 PMC3594938__F5 Cell type-specific outcomes of KSHV interactions with CD36 and CD147 signaling pathways ENSG00000135218 ENSG00000010810 ENSG00000198793 PMC12034555__F3 EVs derived from TNBC cells line can transfer various biomolecules to recipient cells, thereby modulated their biological functions ENSG00000178860 ENSG00000197043 ENSG00000173757 ENSG00000171791 ENSG00000175097 ENSG00000146648 PMC4635569__F1 Proteins used in this study ENSG00000000971 PMC11512255__F6 Schematic model illustrates the mechanism by which HSV-2 UL24 blocks the IRF-3 signaling pathway ENSG00000183735 ENSG00000088888 PMC11580516__F1 Metabolic Reprogramming and Drug Resistance in Breast Cancer ENSG00000131473 ENSG00000143252 ENSG00000198793 ENSG00000155792 ENSG00000168610 ENSG00000115419 ENSG00000159399 PMC6776918__F1 Mechanisms linking HPA axis dysregulation and AD ENSG00000142192 ENSG00000145321 PMC11580516__F2 Metabolic Reprogramming of Immune Cells in the Hypoxic Tumor Microenvironment ENSG00000081041 ENSG00000111537 ENSG00000118520 ENSG00000168610 PMC10308769__F1 First reported double drug–drug interaction in a cancer renal patient under everolimus treatment: therapeutic drug monitoring and review of literature ENSG00000177169 ENSG00000169047 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC1852756__F2 The small nuclear ribonucleoprotein biogenesis pathway ENSG00000164902 ENSG00000137574 ENSG00000164949 ENSG00000132341 PMC3608184__F1 Cardioprotective mechanisms of T3 ENSG00000198793 PMC8060499__F1 Possible involvement of the complement system (CS) in the recruitment of neutrophils and the formation of NETs in Alzheimer's disease ENSG00000203710 ENSG00000062485 PMC3837441__F7 The Cdc42-dependent regulation of neural differentiation in P19 cells ENSG00000070831 ENSG00000198793 ENSG00000273529 PMC3722174__F8 Primary Respiratory Chain Disease Causes Tissue-Specific Dysregulation of the Global Transcriptome and Nutrient-Sensing Signaling Network ENSG00000150907 ENSG00000169047 ENSG00000096717 ENSG00000106459 PMC1914109__F8 The p110D → RhoA → PTEN signalling pathway described in the text ENSG00000291971 PMC4967210__F5 Ingenuity Pathways Analysis of the effects of TXNIP deletion ENSG00000128052 ENSG00000169710 ENSG00000265972 ENSG00000124762 PMC5979596__F3A GFRA1: A Novel Molecular Target for the Prevention of Osteosarcoma Chemoresistance ENSG00000010810 PMC6391732__F3 Notch signaling pathway as seen in the KEGG database (hsa:04330) ENSG00000273529 ENSG00000133961 ENSG00000114315 PMC7395689__F1 Figure describes the process by which AVB3 mediates prostate cancer cell metastasis ENSG00000108691 ENSG00000161921 ENSG00000291971 ENSG00000113140 ENSG00000198793 ENSG00000203727 PMC2453100__F7 The activated PI3K-AKT pathway and its downstream effectors that contribute to the tumorigenesis of TSHomas in TRBPV/PV mice ENSG00000002330 ENSG00000198793 PMC11900819__S4 Proposed organization and role of adenosine receptors in mitochondria ENSG00000133937 PMC3022823__F9 FBPA clustering on gene expression in the bystander response ENSG00000104856 ENSG00000128016 ENSG00000204116 ENSG00000127528 ENSG00000168811 ENSG00000124762 ENSG00000141968 ENSG00000245848 ENSG00000144802 ENSG00000172216 ENSG00000136997 ENSG00000130222 ENSG00000173535 ENSG00000185591 ENSG00000092067 ENSG00000130513 ENSG00000005339 ENSG00000116044 ENSG00000173039 ENSG00000221869 ENSG00000106511 ENSG00000073756 ENSG00000169715 ENSG00000260027 ENSG00000177606 ENSG00000114166 PMC3022823__F7 FBPA clustering on gene expression after direct irradiation ENSG00000157554 ENSG00000104856 ENSG00000141384 ENSG00000117139 ENSG00000276644 ENSG00000196591 ENSG00000127528 ENSG00000162772 ENSG00000166886 ENSG00000106546 ENSG00000157557 ENSG00000144802 ENSG00000172216 ENSG00000078900 ENSG00000136997 ENSG00000163734 ENSG00000168310 ENSG00000140464 ENSG00000081041 ENSG00000148400 ENSG00000197632 ENSG00000173039 ENSG00000162924 ENSG00000106511 ENSG00000125347 ENSG00000212916 ENSG00000123685 ENSG00000067066 ENSG00000102034 ENSG00000177606 PMC4774109__F2 Dysfunctional humoral response during visceral leishmaniasis ENSG00000139193 ENSG00000145321 PMC8151274__F4 MiR-21 in the Cancers of the Digestive System and Its Potential Role as a Diagnostic, Predictive, and Therapeutic Biomarker ENSG00000132906 ENSG00000002330 ENSG00000134982 ENSG00000113318 ENSG00000164305 PMC2997737__F1 AKT/MTOR pathway ENSG00000119487 ENSG00000005882 ENSG00000169047 ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC7982729__F4 Autophagy-mediated elimination of pathogens ENSG00000183735 ENSG00000164430 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC12021660__F2 Fat-body metabolic pathway profiling ENSG00000131473 ENSG00000141086 PMC8808015__F1 Wnt Signaling Pathway and ROR2 Receptor in Embryonic Development: An Update Review Article ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000100592 ENSG00000134982 ENSG00000185483 ENSG00000074410 PMC10040851__F6 Single-cell atlas reveals shared and distinct immune responses and metabolic profiles in SARS-CoV-2 and HIV-1 infections ENSG00000173821 ENSG00000213928 ENSG00000105835 ENSG00000075142 ENSG00000134982 ENSG00000197746 ENSG00000137200 ENSG00000147133 ENSG00000160710 ENSG00000205413 ENSG00000196396 ENSG00000142166 ENSG00000188313 ENSG00000188404 ENSG00000079950 ENSG00000137161 ENSG00000118898 ENSG00000177575 ENSG00000151657 ENSG00000173786 ENSG00000129226 ENSG00000276561 ENSG00000163412 ENSG00000019582 ENSG00000155287 ENSG00000060491 ENSG00000197296 ENSG00000118503 ENSG00000010810 ENSG00000123609 ENSG00000059378 ENSG00000015285 ENSG00000142089 ENSG00000026751 ENSG00000256646 ENSG00000132963 PMC9118092__F8 Inhibition of activin A receptor signalling attenuates age-related pathological cardiac remodelling ENSG00000283887 ENSG00000156076 ENSG00000130649 ENSG00000103375 ENSG00000179542 ENSG00000271303 ENSG00000006327 ENSG00000106631 PMC9456318__F9 Integrated Analysis of Transcriptome and Metabolome Reveals Distinct Responses of Pelteobagrus fulvidraco against Aeromonas veronii Infection at Invaded and Recovering Stage ENSG00000145604 ENSG00000149311 ENSG00000087095 ENSG00000127528 ENSG00000123374 ENSG00000145782 PMC9943254__F2 Recent progress in the development of nanomaterials targeting multiple cancer metabolic pathways: a review of mechanistic approaches for cancer treatment ENSG00000141867 ENSG00000136997 ENSG00000169710 ENSG00000103257 ENSG00000115419 PMC7459801__F1 Processing and trafficking of amyloid precursor protein (APP) through the endolysosomal pathway ENSG00000142192 ENSG00000143801 PMC3979327__F3 MicroRNA networks regulate development of brown adipocytes ENSG00000111049 ENSG00000037965 ENSG00000171720 PMC7766831__F5 Proposed model of the molecular and cellular responses to new replication stress inhibitors ENSG00000143799 ENSG00000175054 ENSG00000138385 PMC5376429__F2 Emerging signaling pathways in HCC: chromatin remodeling: restricting transcriptional and DNA condensation occurs as a result of histone deacetylation catalyzed by HDACs in nucleosome ENSG00000186575 ENSG00000136869 ENSG00000150457 ENSG00000131023 ENSG00000189079 PMC9943254__F8 Recent progress in the development of nanomaterials targeting multiple cancer metabolic pathways: a review of mechanistic approaches for cancer treatment ENSG00000164690 ENSG00000128602 PMC11621776__F4 Important AM pathways ENSG00000144063 ENSG00000122966 ENSG00000172005 ENSG00000026103 PMC11621776__F6 Five signaling pathways associated with macrophage polarization which are highlighted by pink color ENSG00000111537 ENSG00000137033 ENSG00000111713 PMC2771360__F4 Microglia Are Mediators of Borrelia burgdorferi–Induced Apoptosis in SH-SY5Y Neuronal Cells ENSG00000104499 ENSG00000149311 ENSG00000175054 ENSG00000152409 ENSG00000179091 ENSG00000135446 ENSG00000064393 ENSG00000132646 ENSG00000168036 ENSG00000078237 ENSG00000284194 PMC4770774__F9 Stromal cells promote anti-estrogen resistance of breast cancer cells through an insulin-like growth factor binding protein 5 (IGFBP5)/B-cell leukemia/lymphoma 3 (Bcl-3) axis ENSG00000178860 ENSG00000115461 ENSG00000140443 PMC8710987__F3 Metabolic dysregulation in bronchopulmonary dysplasia: Implications for identification of biomarkers and therapeutic approaches PMC11979968__F4 Distribution of the seven core targets in the serotonergic synapse signaling pathway and the drug‐pathway‐target‐disease network ENSG00000169291 ENSG00000100985 ENSG00000146648 PMC9553391__F8 Anlotinib Benefits the APDL1 Immunotherapy by Activating ROS/JNK/AP-1 Pathway to Upregulate PDL1 Expression in Colorectal Cancer ENSG00000081041 ENSG00000177606 PMC5452357__F4 Scheme showed the probably metabolic pathways in patient with PH2 and AGXT2 deficiency ENSG00000113492 ENSG00000173599 PMC6522898__F10 Schematic illustrating the mechanism in which elevated HP induces apoptosis in RGCs through the regulation of the NGF signalling pathway ENSG00000150907 PMC6311083__F4 Qualitative Biological Regulatory Network (BRN) of Hexosamine Biosynthetic Pathway (HBP) intersection with PI3K-mTOR-Myc signaling and P53-MDM2 signalling axis ENSG00000147162 ENSG00000198408 PMC7784512__F4 Schematic proposed mechanism of inflammatory downstream signaling pathway in lung epithelial cells undergoing hypoxia–reperfusion stimulation ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC4609742__F9 Model depicting the functional interplay between PPM1G, the 7SK snRNP, and ATM kinase during the activation of the NFKB transcriptional program in response to DNA damage ENSG00000174720 ENSG00000149311 ENSG00000101751 ENSG00000146834 PMC9231409__F1 Characterization of SARS-CoV-2 Evasion: Interferon Pathway and Therapeutic Options ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000187608 ENSG00000132661 ENSG00000105397 ENSG00000115415 ENSG00000110713 ENSG00000121060 ENSG00000213024 ENSG00000164342 ENSG00000142166 PMC5512163__F2 Biologic and Clinical Perspectives on Thyroid Cancer ENSG00000157764 ENSG00000198793 PMC5216790__F6 Frizzled2 signaling regulates growth of high-risk neuroblastomas by interfering with Beta-catenin-dependent and Beta-catenin-independent signaling pathways ENSG00000154342 ENSG00000281324 ENSG00000169071 ENSG00000136997 ENSG00000185483 ENSG00000168036 PMC9166437__F1 TREM2 in the pathogenesis of AD: a lipid metabolism regulator and potential metabolic therapeutic target ENSG00000197943 PMC11130926__F1 Bacterial Q de novo and salvage pathways ENSG00000165118 ENSG00000151576 PMC5512163__F3 Biologic and Clinical Perspectives on Thyroid Cancer ENSG00000157764 ENSG00000173674 ENSG00000198793 ENSG00000164362 PMC6066558__F4 Soluble klotho pleiotropic functions and FGF23 – sKlotho interactions ENSG00000118972 ENSG00000160867 ENSG00000137672 ENSG00000140443 PMC11653467__F7 Poricoic acid A attenuates renal fibrosis by inhibiting endoplasmic reticulum stress-mediated apoptosis ENSG00000128272 ENSG00000100219 PMC5395695__F1 Proposed mechanisms of pathogenesis in haploinsufficiency of A20 (HA20), otulipenia/otulin-related autoinflammatory syndrome (ORAS), and linear ubiquitin chain assembly complex (LUBAC) deficiencies ENSG00000137275 ENSG00000102871 ENSG00000154124 ENSG00000127191 PMC8468876__F2 Gamma-Aminobutyrate (GABA) Regulated Plant Defense: Mechanisms and Opportunities ENSG00000105953 ENSG00000008130 PMC11149107__F1 HER3 targeted therapies in the clinic and HER3 downstream signaling pathways ENSG00000291971 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC8466973__F1 High temperature requirement A1 in cancer: biomarker and therapeutic target ENSG00000148400 ENSG00000138798 ENSG00000075891 ENSG00000146648 PMC8990718__F6 Serum amyloid A 1 induces suppressive neutrophils through the Toll‐like receptor 2–mediated signaling pathway to promote progression of breast cancer ENSG00000288411 ENSG00000172936 PMC4770016__F2 ITK acts as a rheostat for the TCR signaling pathway ENSG00000291603 ENSG00000137265 ENSG00000113263 PMC11594203__F6 Differentially expressed genes related to mammary epithelial cell proliferation and milk protein synthesis in the PI3K-Akt, WNT, and mTOR signaling pathways after knockdown of S100A9 in MAC-T cells ENSG00000123643 ENSG00000281324 ENSG00000116586 ENSG00000163220 ENSG00000198793 ENSG00000155792 ENSG00000123374 ENSG00000136869 ENSG00000161202 PMC7934064__F2 Mechanisms involved in DDR and checkpoint immunotherapies ENSG00000143799 ENSG00000149311 ENSG00000175054 ENSG00000164430 ENSG00000149554 PMC7352439__F2 Metabolic characteristics of M1 and M2 macrophages ENSG00000113520 ENSG00000026103 PMC12210716__F1 Jak-STAT signaling pathway ENSG00000159128 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000027697 ENSG00000142166 PMC5845129__F1 Schematic diagram for innate immune response against influenza A virus (IAV) infection ENSG00000088888 ENSG00000105397 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC6073271__F1 Simplified diagram of the 2-C-methyl-d-erythritol-4-phosphate (MEP) pathway for phytohormone abscisic acid (ABA) biosynthesis with components occurring in the Chloroplast and Cytosol ENSG00000197429 PMC8710987__F1 Metabolic dysregulation in bronchopulmonary dysplasia: Implications for identification of biomarkers and therapeutic approaches ENSG00000180210 ENSG00000197713 ENSG00000153574 PMC6032434__F6 Summary and model for the potential function of the chIL-34 signaling pathway ENSG00000115415 ENSG00000168610 PMC4086483__F1 NFKB signaling pathway ENSG00000186716 PMC9248717__F2 Wnt Signaling in Postnatal Tooth Root Development ENSG00000164879 ENSG00000177606 PMC9248717__F1 Wnt Signaling in Postnatal Tooth Root Development ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC7878563__F6 Signaling pathways coupled to the M4 mAChR PMC7878563__F5 Signaling pathways coupled to the M1 mAChR PMC7192886__F1 Immune responses induced by radiotherapy ENSG00000149311 ENSG00000175054 ENSG00000164430 ENSG00000111537 ENSG00000189403 ENSG00000136869 ENSG00000125347 ENSG00000146648 PMC6585493__F2 Transcriptional changes of genes involved in fatty acid catabolism, MVA formation, and energy metabolism by ΔYPL062W, whose reactions mainly occur in the peroxisome (A), cytoplasm (B), and mitochondrion (C), respectively ENSG00000067064 ENSG00000197429 ENSG00000128513 PMC9630645__F3 Therapeutic applications and potential mechanisms of acupuncture in migraine: A literature review and perspectives ENSG00000041982 ENSG00000042832 ENSG00000116096 ENSG00000196689 PMC5671379__F1 Damage Associated Molecular Patterns in the Pathogenesis of Osteoarthritis: Potentially Novel Therapeutic Targets ENSG00000143546 ENSG00000163220 ENSG00000189403 ENSG00000175104 PMC9628128__F1 Warburg effect in colorectal cancer: the emerging roles in tumor microenvironment and therapeutic implications ENSG00000180210 ENSG00000134982 ENSG00000138798 ENSG00000136997 ENSG00000168036 ENSG00000146648 ENSG00000159399 PMC6346072__F1 Metabolism of sulfur amino acids and H2S synthesis PMC7404291__F4 HSV-1 evasion mechanisms to downregulate the host innate immune response ENSG00000213928 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 PMC8595937__F1 Bruton’s Tyrosine Kinase (BTK) Inhibitors and Autoimmune Diseases: Making Sense of BTK Inhibitor Specificity Profiles and Recent Clinical Trial Successes and Failures ENSG00000107562 ENSG00000291603 ENSG00000070831 ENSG00000067900 ENSG00000105639 ENSG00000291420 ENSG00000141968 ENSG00000010671 ENSG00000121966 ENSG00000089159 ENSG00000149269 ENSG00000010810 ENSG00000163914 ENSG00000137076 ENSG00000090924 ENSG00000113263 PMC7120249__F1 Immune-related autophagy functions ENSG00000167207 ENSG00000125538 ENSG00000136869 ENSG00000237693 PMC5512069__F8 The role of BMP4 in regulating hyperandrogenism development ENSG00000170365 PMC10838060__F6 cGAS-STING and pyroptosis ENSG00000278718 ENSG00000162711 ENSG00000183735 ENSG00000163568 PMC10838060__F7 cGAS-STING pathway and metabolic reprogramming ENSG00000005882 ENSG00000102794 PMC10838060__F4 Other media for activating STING ENSG00000183735 ENSG00000164430 ENSG00000163565 ENSG00000175104 ENSG00000253729 PMC10838060__F8 cGAS-STING and cell senescence in diabetes ENSG00000183735 ENSG00000164430 ENSG00000144554 PMC10838060__F9 CGAS-STING pathway in diabetic complications ENSG00000162711 ENSG00000183735 ENSG00000164430 PMC6684391__F6 Proposed interaction induced by azithromycin (AZM) is depicted ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000125538 ENSG00000173039 ENSG00000172936 ENSG00000136869 PMC8830521__F4 Apoptosis Induction, a Sharp Edge of Berberine to Exert Anti-Cancer Effects, Focus on Breast, Lung, and Liver Cancer ENSG00000162711 ENSG00000087245 ENSG00000132646 ENSG00000125538 ENSG00000198793 ENSG00000100985 ENSG00000168610 PMC5606204__F4 Regulated Cell Death Pathways ENSG00000132906 ENSG00000196954 ENSG00000120868 ENSG00000168040 ENSG00000064012 ENSG00000164305 ENSG00000285379 PMC2812385__F7 Alternative mechanisms exist for the induction of inflammatory and apoptotic genes in the absence of the IFNA/B receptor during influenza virus infection ENSG00000104856 ENSG00000196954 ENSG00000173039 ENSG00000175592 ENSG00000125347 ENSG00000276561 ENSG00000007171 ENSG00000153487 ENSG00000108691 ENSG00000115415 ENSG00000136997 ENSG00000125538 ENSG00000111341 ENSG00000100985 ENSG00000140464 PMC5426484__F3 Network fabricated in CellDesigner ENSG00000105662 PMC1851974__F2 Regulation of cyclin D1 degradation ENSG00000174989 ENSG00000135446 ENSG00000105810 ENSG00000105204 PMC8830521__F5 Apoptosis Induction, a Sharp Edge of Berberine to Exert Anti-Cancer Effects, Focus on Breast, Lung, and Liver Cancer ENSG00000145388 PMC8830521__F6 Apoptosis Induction, a Sharp Edge of Berberine to Exert Anti-Cancer Effects, Focus on Breast, Lung, and Liver Cancer ENSG00000136997 ENSG00000168036 ENSG00000040199 ENSG00000128602 PMC3789860__F3 Shaping neurons: Long and short range effects of mature and proBDNF signalling upon neuronal structure ENSG00000038382 PMC3582714__F1 Sensing the immune microenvironment to coordinate T cell metabolism, differentiation & function ENSG00000136997 ENSG00000164327 PMC5945848__F8 P2RX7-MAPK1/2-SP1 axis inhibits MTOR independent HSPB1-mediated astroglial autophagy ENSG00000177169 ENSG00000097033 ENSG00000105664 ENSG00000089041 ENSG00000185591 ENSG00000132356 PMC4396872__F1 Canonical and noncanonical NLR inflammasome activation ENSG00000115415 ENSG00000125538 PMC5627515__F3 Protein-bound uremic toxins could take use of five potential toxin-conjugated albumin-receptor pathways to either promote or suppress inflammation ENSG00000070831 ENSG00000291971 ENSG00000113140 PMC4396872__F3 NOD signaling pathways ENSG00000088888 ENSG00000167207 ENSG00000157625 ENSG00000131323 ENSG00000276561 PMC9475348__F6 Human placental mesenchymal stem cells regulate inflammation via the NF‑KB signaling pathway ENSG00000125538 ENSG00000136869 PMC12032003__F7 Working model of G-Rg1’s functions in protecting the synaptic plasticity and mitigating neuroapoptosis via the Hippo-YAP signaling pathway in the stress model ENSG00000197905 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC8471828__F6 Ferroptosis Meets Cell–Cell Contacts ENSG00000150457 ENSG00000131023 PMC4206829__F4 Recent advances in understanding colitis-associated tumorigenesis ENSG00000168036 ENSG00000136869 ENSG00000168610 PMC10788715__F5 MiRNA-766-3p inhibited gastric cancer via targeting COL1A1 and regulating the PI3K/AKT signaling pathway ENSG00000139219 ENSG00000058085 ENSG00000169031 ENSG00000197565 ENSG00000081052 ENSG00000134871 ENSG00000108821 ENSG00000172037 PMC9456412__F2 Lipid-Based Molecules on Signaling Pathways in Autism Spectrum Disorder PMC4543753__F4 Transcriptional gene regulatory network in VBL-treated KB-3 cell ENSG00000109320 ENSG00000173039 ENSG00000085662 ENSG00000291420 ENSG00000124762 ENSG00000186847 ENSG00000168461 ENSG00000102007 ENSG00000135404 ENSG00000102316 ENSG00000108671 ENSG00000173692 ENSG00000134531 PMC6249341__F1 Implication of microglia in the development of Alzheimer's disease ENSG00000162711 ENSG00000142192 ENSG00000125538 ENSG00000136869 PMC7737398__F9 Pathways of ES and SR PMC9495382__F2 p53: From Fundamental Biology to Clinical Applications in Cancer ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000105810 PMC4534355__F5 Distilling a Visual Network of Retinitis Pigmentosa Gene-Protein Interactions to Uncover New Disease Candidates ENSG00000126016 ENSG00000150991 ENSG00000089157 PMC4390248__F5 Representative protein-protein interaction networks of key pathways and proteins involved in sperm functions ENSG00000166794 ENSG00000120885 PMC7868042__F2 Autophagy in kidney homeostasis and disease ENSG00000188554 ENSG00000158828 ENSG00000069509 PMC10967382__F5 Altered sphingolipid metabolism and signaling in monocytes and neutrophils during pneumonia ENSG00000174125 ENSG00000167769 ENSG00000162711 ENSG00000171791 ENSG00000183018 ENSG00000198964 ENSG00000117020 ENSG00000100596 ENSG00000173599 ENSG00000164023 ENSG00000136869 ENSG00000172936 ENSG00000166224 ENSG00000078124 ENSG00000148154 ENSG00000175104 ENSG00000172296 PMC8267750__F4 Fructose and the Liver ENSG00000162711 ENSG00000125538 ENSG00000172936 PMC8714903__F2 Impact of Bartonella VirB/VirD4 Type IV Secretion System Effectors on Eukaryotic Host Cells ENSG00000168610 PMC4445861__F2 Slit/Robo interactions and their roles in carcinogenesis ENSG00000124102 ENSG00000019991 ENSG00000087245 ENSG00000145147 ENSG00000070831 ENSG00000168036 ENSG00000100985 ENSG00000121966 PMC12037536__F5 Multiple cytokines and signaling pathways in psoriasis is highly significant ENSG00000159128 ENSG00000102871 ENSG00000177663 ENSG00000168610 ENSG00000163702 ENSG00000138378 ENSG00000105397 ENSG00000172005 ENSG00000154059 ENSG00000172936 ENSG00000131323 ENSG00000056736 ENSG00000175104 PMC8727737__F2 JAK/STAT of all trades: linking inflammation with cancer development, tumor progression and therapy resistance ENSG00000196090 ENSG00000198793 PMC4024059__F1 STAT3 and epithelial–mesenchymal transitions in carcinomas ENSG00000145623 ENSG00000099985 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC3681753__F8 Genome-wide RNAi Screen Reveals a New Role of a WNT/CTNNB1 Signaling Pathway as Negative Regulator of Virus-induced Innate Immune Responses ENSG00000164638 ENSG00000172830 ENSG00000146859 ENSG00000134982 ENSG00000168036 ENSG00000165816 ENSG00000067646 ENSG00000172468 ENSG00000109066 ENSG00000162139 ENSG00000067842 ENSG00000106327 ENSG00000184634 ENSG00000162747 ENSG00000064012 ENSG00000071655 ENSG00000284832 ENSG00000054690 ENSG00000084110 ENSG00000168040 ENSG00000102172 ENSG00000225950 ENSG00000061938 ENSG00000175166 ENSG00000185231 ENSG00000172057 ENSG00000131323 ENSG00000175104 ENSG00000121060 ENSG00000196407 PMC8313795__F1 Chitosan derivatives: A suggestive evaluation for novel inhibitor discovery against wild type and variants of SARS-CoV-2 virus ENSG00000140564 ENSG00000130234 ENSG00000184012 PMC6687759__F3 Proteoglycans in cancer-predicted pathway ENSG00000110395 ENSG00000136997 ENSG00000112715 ENSG00000146648 PMC5878997__F3 Extranuclear Signaling by Sex Steroid Receptors and Clinical Implications in Breast Cancer ENSG00000291971 ENSG00000138798 ENSG00000123374 ENSG00000185591 ENSG00000146648 PMC7559203__F3 KSHV-deregulated NFKB signaling pathway in oncogenesis ENSG00000213658 ENSG00000137265 ENSG00000171791 ENSG00000168610 ENSG00000121966 PMC7559203__F1 an overview of virus-deregulated NFKB signaling pathway in oncogenesis ENSG00000104856 ENSG00000133116 ENSG00000171791 ENSG00000125968 PMC7559203__F2 EBV-deregulated NFKB signaling pathway in oncogenesis ENSG00000213658 ENSG00000145321 PMC2949129__F7 Putative signaling pathways leading to translational activation and enhanced MCT2 protein synthesis after BDNF treatment in cultured cortical neurons ENSG00000198793 PMC8964062__F1 T Cell Metabolism in Infection ENSG00000150907 ENSG00000136997 ENSG00000159399 PMC8450894__F2 Gut Microbiota in Adipose Tissue Dysfunction Induced Cardiovascular Disease: Role as a Metabolic Organ ENSG00000170458 ENSG00000136869 PMC9132726__F1 Control of the Hedgehog pathway by compartmentalized PKA in the primary cilium ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC4563137__F5 Pathway enrichment analysis reveals PI3K/PTEN/AKT signalling and apoptosis pathway as the most significantly related pathway ENSG00000140992 ENSG00000115904 ENSG00000150093 ENSG00000160691 PMC9132726__F2 Control of the Hedgehog pathway by compartmentalized PKA in the primary cilium ENSG00000143147 ENSG00000128602 PMC6777507__F2 Activation of serotonin receptors (5-HT-R) initiates a signaling cascade that leads to the activation of extracellular signal-regulated kinases (ERK) ENSG00000142192 PMC9132726__F3 Control of the Hedgehog pathway by compartmentalized PKA in the primary cilium ENSG00000106524 ENSG00000143147 ENSG00000147256 ENSG00000128602 ENSG00000113448 ENSG00000026103 PMC4619565__F7 Parallel activin and TGFB signaling in advanced colon cancer PMC6850218__F1 Model illustrating 4 potential roles of RGD-binding integrins in the initiation, development, and perpetuation of organ fibrosis PMC5527674__F1 “Pushmi-Pullyu” of DNA REPAIR: Clinical Synthetic Lethality ENSG00000143799 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000291803 ENSG00000051180 ENSG00000149554 ENSG00000067369 ENSG00000183765 PMC7823564__F1 NFKB canonical and non-canonical pathways ENSG00000104856 ENSG00000138798 ENSG00000111321 ENSG00000146648 PMC8247594__F2 Evolution of Our Understanding of XIAP Deficiency PMC8247594__F3 Evolution of Our Understanding of XIAP Deficiency ENSG00000112977 ENSG00000162711 ENSG00000167207 ENSG00000157625 ENSG00000136869 ENSG00000168040 ENSG00000112186 ENSG00000127191 ENSG00000285379 ENSG00000142166 PMC8306787__F3 Long Non-Coding RNAs and the Molecular Mechanisms Involved in Insulin Resistance ENSG00000150782 ENSG00000128272 ENSG00000134013 ENSG00000122877 ENSG00000160741 ENSG00000026103 PMC3819805__F11 Folate biosynthetic pathway in Plasmodium falciparum ENSG00000228716 ENSG00000095059 PMC7167343__F1 Androgen metabolism scheme ENSG00000171234 ENSG00000042832 ENSG00000197888 ENSG00000196620 PMC8686808__F2 Risk surveillance and mitigation: autoantibodies as triggers and inhibitors of severe reactions to SARS-CoV-2 infection ENSG00000110799 ENSG00000134982 ENSG00000079432 ENSG00000005381 PMC2617762__F6 Impaired Nuclear Nrf2 Translocation Undermines the Oxidative Stress Response in Friedreich Ataxia ENSG00000178573 ENSG00000247077 ENSG00000079999 PMC8306787__F4 Long Non-Coding RNAs and the Molecular Mechanisms Involved in Insulin Resistance ENSG00000128272 ENSG00000134013 ENSG00000173599 ENSG00000160741 ENSG00000026103 PMC7847180__F8 Network analysis ENSG00000203747 ENSG00000130202 ENSG00000130396 ENSG00000138798 ENSG00000100852 ENSG00000198125 ENSG00000165322 PMC2866107__F5 Current Status of Xenotransplantation and Prospects for Clinical Application ENSG00000003436 ENSG00000110799 ENSG00000134982 PMC8120744__F4 Upregulated anti-angiogenic miR-424-5p in type 1 diabetes (model of subclinical cardiovascular disease) correlates with endothelial progenitor cells, CXCR1/2 and other parameters of vascular health ENSG00000163464 ENSG00000171105 ENSG00000112715 ENSG00000150630 PMC4211615__F1 EMT-associated signaling molecules in glioma cell ENSG00000019991 ENSG00000041982 ENSG00000138798 ENSG00000026508 ENSG00000168610 ENSG00000146648 ENSG00000121966 PMC6994339__F1 Filtering through the role of NRF2 in kidney disease ENSG00000181019 ENSG00000100387 ENSG00000023909 ENSG00000079999 PMC6955051__F3 Role of interleukins in heart failure with reduced ejection fraction ENSG00000137033 ENSG00000134070 ENSG00000172936 ENSG00000162692 PMC8236958__F6 Identification of Regulatory Functions of LncRNAs Associated With T. circumcincta Infection in Adult Sheep ENSG00000069482 ENSG00000291971 ENSG00000163914 ENSG00000026508 PMC2736291__F2 Diagram shows the cell signaling pathways, which were involved in postconditioning ENSG00000002330 ENSG00000168036 PMC6681682__F2 Functional networks overrepresented in the list of DE mRNA in response to infection of bMDMs with Streptococcus agalactiae strain ST103 compared to uninfected controls ENSG00000110944 ENSG00000169908 ENSG00000276725 ENSG00000133574 ENSG00000152213 ENSG00000141577 ENSG00000112992 ENSG00000111348 ENSG00000147894 ENSG00000072571 ENSG00000153140 ENSG00000162729 ENSG00000158966 ENSG00000204131 ENSG00000100354 ENSG00000119397 ENSG00000146955 ENSG00000274334 ENSG00000182504 ENSG00000166145 ENSG00000167037 ENSG00000123810 ENSG00000133816 ENSG00000276111 ENSG00000109103 ENSG00000134698 ENSG00000127838 ENSG00000157827 ENSG00000283934 ENSG00000092847 ENSG00000137841 ENSG00000214114 ENSG00000145839 ENSG00000069482 ENSG00000120805 ENSG00000096872 ENSG00000123609 ENSG00000198846 ENSG00000142149 ENSG00000138080 ENSG00000134108 ENSG00000138801 PMC11655346__F1 Unique role of DLL3 in the notch signaling pathway ENSG00000168214 ENSG00000137845 ENSG00000090932 ENSG00000139352 PMC8005123__F2 Molecular pathways of SMC-mediated migration and proliferation ENSG00000168329 ENSG00000069812 ENSG00000145321 ENSG00000273529 ENSG00000114315 PMC2924816__F1 Quantification of Beta-Catenin Signaling Components in Colon Cancer Cell Lines, Tissue Sections, and Microdissected Tumor Cells using Reaction Monitoring Mass Spectrometry ENSG00000137673 ENSG00000134982 ENSG00000026508 ENSG00000168036 ENSG00000101266 ENSG00000168646 PMC6826333__F1 Network of Beta-elemene-target genes ENSG00000171246 ENSG00000137857 ENSG00000066926 ENSG00000143318 ENSG00000140279 ENSG00000080819 ENSG00000158578 ENSG00000256269 ENSG00000166006 ENSG00000009709 ENSG00000136541 ENSG00000105662 ENSG00000197586 ENSG00000092439 ENSG00000142192 ENSG00000104321 ENSG00000074621 ENSG00000197635 ENSG00000248144 ENSG00000166947 ENSG00000116157 ENSG00000104888 ENSG00000132170 ENSG00000106617 ENSG00000188021 ENSG00000136848 ENSG00000162105 ENSG00000292254 ENSG00000137801 ENSG00000123374 ENSG00000102104 ENSG00000026103 ENSG00000161544 ENSG00000116729 ENSG00000112335 ENSG00000244165 ENSG00000134780 ENSG00000177301 ENSG00000132840 ENSG00000109738 ENSG00000102003 ENSG00000006534 ENSG00000086232 ENSG00000135446 ENSG00000124089 ENSG00000165917 ENSG00000129152 ENSG00000037757 ENSG00000006016 ENSG00000182674 ENSG00000136531 ENSG00000057294 ENSG00000046604 ENSG00000123999 ENSG00000081026 ENSG00000125686 ENSG00000162951 ENSG00000132744 ENSG00000070729 ENSG00000131409 ENSG00000078808 ENSG00000160460 ENSG00000275165 ENSG00000165246 ENSG00000129194 ENSG00000152266 ENSG00000166342 ENSG00000164603 ENSG00000242252 ENSG00000112964 ENSG00000154240 ENSG00000171385 ENSG00000158286 ENSG00000168874 ENSG00000182963 ENSG00000116996 ENSG00000158828 ENSG00000184454 ENSG00000099864 ENSG00000116783 ENSG00000168671 ENSG00000169760 ENSG00000124205 ENSG00000198515 ENSG00000129159 ENSG00000292214 ENSG00000116396 ENSG00000186795 ENSG00000283859 ENSG00000223572 ENSG00000239474 ENSG00000150672 ENSG00000110076 ENSG00000108797 ENSG00000198728 ENSG00000133027 ENSG00000012061 ENSG00000152661 ENSG00000107562 ENSG00000135218 ENSG00000185313 ENSG00000109819 ENSG00000150782 ENSG00000149089 ENSG00000134755 ENSG00000149968 ENSG00000158321 ENSG00000128918 ENSG00000196839 ENSG00000081189 ENSG00000116984 ENSG00000151224 ENSG00000141480 ENSG00000170743 ENSG00000067606 ENSG00000161647 ENSG00000104884 ENSG00000175206 ENSG00000147862 ENSG00000171723 ENSG00000108389 ENSG00000177807 ENSG00000158445 ENSG00000136826 ENSG00000134899 ENSG00000109103 ENSG00000001626 ENSG00000144191 ENSG00000109756 ENSG00000152332 ENSG00000166862 ENSG00000116237 ENSG00000140274 ENSG00000283100 ENSG00000120063 ENSG00000170458 ENSG00000164326 ENSG00000123505 ENSG00000011347 ENSG00000136854 ENSG00000087085 ENSG00000172572 ENSG00000169032 ENSG00000099822 ENSG00000149295 ENSG00000131730 ENSG00000161681 ENSG00000177272 ENSG00000184845 ENSG00000185052 ENSG00000143761 ENSG00000182255 ENSG00000079950 ENSG00000132535 ENSG00000154743 ENSG00000198286 ENSG00000130208 ENSG00000147044 ENSG00000084093 ENSG00000166257 ENSG00000147437 ENSG00000111262 ENSG00000138622 ENSG00000172955 ENSG00000127022 ENSG00000187961 ENSG00000182621 ENSG00000087460 ENSG00000004848 ENSG00000111725 ENSG00000115592 ENSG00000178919 ENSG00000115850 ENSG00000156113 ENSG00000135517 ENSG00000164535 ENSG00000130528 ENSG00000120885 ENSG00000188372 ENSG00000165527 ENSG00000112038 ENSG00000159197 ENSG00000138380 ENSG00000262785 ENSG00000143420 ENSG00000198860 ENSG00000103375 ENSG00000189056 ENSG00000121905 ENSG00000171303 ENSG00000158467 ENSG00000036565 ENSG00000143553 ENSG00000019991 ENSG00000184254 ENSG00000204842 ENSG00000036672 ENSG00000130649 ENSG00000102359 ENSG00000179295 ENSG00000180210 ENSG00000196344 ENSG00000125538 ENSG00000124275 ENSG00000087250 ENSG00000118520 ENSG00000171560 ENSG00000163399 ENSG00000145708 ENSG00000126457 ENSG00000021645 ENSG00000198626 ENSG00000168040 ENSG00000073921 ENSG00000127191 ENSG00000131398 ENSG00000010810 ENSG00000171759 ENSG00000187758 ENSG00000144290 ENSG00000185149 PMC6826333__F2 Network of pancreatic cancer-target genes ENSG00000261857 ENSG00000134982 ENSG00000163599 ENSG00000169047 ENSG00000171791 ENSG00000145113 ENSG00000124762 ENSG00000006695 ENSG00000125398 ENSG00000082175 ENSG00000157227 ENSG00000173599 ENSG00000139515 ENSG00000115138 ENSG00000001626 ENSG00000064012 ENSG00000140443 ENSG00000293532 ENSG00000110711 ENSG00000085117 ENSG00000137275 ENSG00000146469 ENSG00000184956 ENSG00000110680 ENSG00000160181 ENSG00000157017 ENSG00000132693 ENSG00000135480 ENSG00000132170 ENSG00000189283 ENSG00000162009 ENSG00000274247 ENSG00000161634 ENSG00000163235 ENSG00000132646 ENSG00000174059 ENSG00000145247 ENSG00000138722 ENSG00000173404 ENSG00000153094 ENSG00000291971 ENSG00000164251 ENSG00000149294 ENSG00000196154 ENSG00000150093 ENSG00000047936 ENSG00000169032 ENSG00000112715 ENSG00000121879 ENSG00000164305 ENSG00000137801 ENSG00000129757 ENSG00000011422 ENSG00000128052 ENSG00000163394 ENSG00000146678 ENSG00000123374 ENSG00000185591 ENSG00000026103 ENSG00000132906 ENSG00000148346 ENSG00000115008 ENSG00000137673 ENSG00000157764 ENSG00000106244 ENSG00000135100 ENSG00000065361 ENSG00000175793 ENSG00000178741 ENSG00000113140 ENSG00000102003 ENSG00000102854 ENSG00000087460 ENSG00000149311 ENSG00000135446 ENSG00000177606 ENSG00000134853 ENSG00000159399 ENSG00000136689 ENSG00000143799 ENSG00000188641 ENSG00000134460 ENSG00000157404 ENSG00000178585 ENSG00000030304 ENSG00000103222 ENSG00000125084 ENSG00000012048 ENSG00000182585 ENSG00000110148 ENSG00000089685 ENSG00000136997 ENSG00000196352 ENSG00000275565 ENSG00000077782 ENSG00000139687 ENSG00000124102 ENSG00000262785 ENSG00000148400 ENSG00000081051 ENSG00000007171 ENSG00000162438 ENSG00000164078 ENSG00000152214 ENSG00000115263 ENSG00000288204 ENSG00000026508 ENSG00000173692 ENSG00000146648 ENSG00000165556 ENSG00000019991 ENSG00000107562 ENSG00000135218 ENSG00000002330 ENSG00000105329 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000167653 ENSG00000145386 ENSG00000166851 ENSG00000118777 ENSG00000110801 ENSG00000121966 ENSG00000171345 ENSG00000179295 ENSG00000104368 ENSG00000074800 ENSG00000148773 ENSG00000125538 ENSG00000164266 ENSG00000113520 ENSG00000189403 ENSG00000051180 ENSG00000121853 ENSG00000106178 ENSG00000006071 ENSG00000133895 ENSG00000010704 ENSG00000100906 ENSG00000109320 ENSG00000123096 ENSG00000263057 ENSG00000073756 ENSG00000168610 ENSG00000145604 ENSG00000066468 ENSG00000108691 ENSG00000111537 ENSG00000160867 ENSG00000121351 ENSG00000167325 ENSG00000164362 ENSG00000048052 ENSG00000164690 ENSG00000128602 PMC7096354__F4 Dysfunctional pathways of miR-15a and miR-24-1 ENSG00000142178 ENSG00000120057 ENSG00000292028 PMC7074686__F1 Interplay of different signalling pathways that enable C ENSG00000147162 PMC8870141__F5 Sympathetic Nerves and Innate Immune System in the Spleen: Implications of Impairment in HIV-1 and Relevant Models PMC8201093__F2 Role and Clinical Implications of the Retinoblastoma (RB)-E2F Pathway in Gastric Cancer ENSG00000112242 ENSG00000156802 ENSG00000205250 ENSG00000106723 ENSG00000282899 PMC8870141__F2 Sympathetic Nerves and Innate Immune System in the Spleen: Implications of Impairment in HIV-1 and Relevant Models ENSG00000121966 ENSG00000164342 PMC5916970__F1 NFKB/Rel and MAPK pathways activation ENSG00000102871 ENSG00000056558 ENSG00000131323 ENSG00000127191 ENSG00000168610 PMC5267440__F1 Molecular regulation of macroautophagy and targets for pharmacological stimulation of the autophagy-lysosomal pathway ENSG00000177169 ENSG00000112561 ENSG00000171791 PMC3048459__F3 TGFB Smad-dependent signaling pathway: TGFB exerts its effect by binding and activating type II receptor (TGFBR2) and then type I receptor (TGFBR1) ENSG00000198742 PMC5634336__F2 The JAK-STAT Pathway: Impact on Human Disease and Therapeutic Intervention ENSG00000138378 ENSG00000105397 ENSG00000105639 ENSG00000168610 PMC6743726__F2 Glutathione and Transsulfuration in Alcohol-Associated Tissue Injury and Carcinogenesis PMC4905414__F1 Simplified model for phosphatidylserine receptor-mediated efferocytosis ENSG00000186074 ENSG00000291919 ENSG00000291918 PMC6480582__F7 Graphic summary for nifedipine-induced lipogenesis on renal tubular cell ENSG00000151726 ENSG00000124479 ENSG00000135218 ENSG00000113161 PMC11915795__F9 Proposed model for SVV antagonizes type I IFN signaling by targeting HDAC4 ENSG00000089127 PMC5021219__F1 MOLECULAR PATHWAYS: JAK/STAT PATHWAY: MUTATIONS, INHIBITORS, AND RESISTANCE PMC6443324__F2 Modulatory mechanisms of TRAIL extrinsic signaling pathway by E3 ligases and deubiquitinases ENSG00000133606 ENSG00000137275 ENSG00000006712 ENSG00000078747 ENSG00000036672 ENSG00000120868 ENSG00000168040 ENSG00000127191 PMC6877906__F1 MyD88-dependent and TRIF-dependent TLR signaling pathways ENSG00000174125 ENSG00000135218 ENSG00000150455 ENSG00000276561 ENSG00000010671 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000134070 ENSG00000157625 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC8107079__F9 CircPVT1 up‐regulation attenuates steroid‐induced osteonecrosis of the femoral head through regulating miR‐21‐5p‐mediated Smad7/TGFB signalling pathway ENSG00000102575 ENSG00000171791 ENSG00000108821 ENSG00000143387 PMC6877906__F2 Proposed model for the role of TLR-mediated innate immune events in regulating the Th1/Th17 and Th2 immune balance ENSG00000088888 ENSG00000136869 ENSG00000164342 PMC6940522__F5 Resveratrol downregulates miR-31 to promote T regulatory cells during prevention of TNBS-induced colitis ENSG00000049323 PMC2713123__F6 Early- and late-phase platelet aggregation regulated through PAR1 ENSG00000163914 ENSG00000173599 PMC10139073__F2 S1PR function in osteogenic cells ENSG00000163914 ENSG00000168036 ENSG00000170989 ENSG00000213694 ENSG00000125910 ENSG00000267534 PMC10139073__F3 Ying and Yang of Sphingosine-1-Phosphate Signalling within the Bone ENSG00000168036 ENSG00000170989 ENSG00000213694 ENSG00000267534 PMC8064175__F5 Sex-specific differences of humoral immunity and transcriptome diversification in older adults vaccinated with inactivated quadrivalent influenza vaccines ENSG00000011600 ENSG00000157601 ENSG00000185745 ENSG00000185885 ENSG00000244731 ENSG00000159189 ENSG00000132693 ENSG00000276561 ENSG00000182326 ENSG00000236625 ENSG00000173369 ENSG00000173372 ENSG00000197296 ENSG00000288512 ENSG00000155659 ENSG00000142089 PMC5998874__F3 Hypotheses of dysfunctional regulation mechanisms of gastric carcinogenesis around XBP1 ENSG00000141448 ENSG00000291971 ENSG00000198793 ENSG00000100219 ENSG00000171791 ENSG00000134285 ENSG00000168610 ENSG00000123268 ENSG00000121966 PMC8000263__F1 Ferroptosis signaling pathway ENSG00000196839 ENSG00000167468 ENSG00000111684 ENSG00000127948 PMC3408426__F10 Metabolic genes regulated by the Met TFs ENSG00000100412 ENSG00000087157 ENSG00000173599 PMC10838060__F2 cGAS-STING pathway and the NFKB pathway ENSG00000149311 ENSG00000177169 ENSG00000183735 ENSG00000119401 ENSG00000132256 ENSG00000175104 PMC8000263__F2 Lipid metabolic pathways that regulate ferroptosis ENSG00000135218 ENSG00000134824 ENSG00000196839 ENSG00000167468 ENSG00000149485 ENSG00000111684 ENSG00000197977 ENSG00000169710 ENSG00000123983 PMC10838060__F3 cGAS-STING and JAK–STAT pathways ENSG00000184979 ENSG00000183735 ENSG00000164430 ENSG00000105397 ENSG00000165799 PMC9208136__F1 Optimizing the downstream MVA pathway using a combination optimization strategy to increase lycopene yield in Escherichia coli ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC5017307__F1 Hedgehog signal transduction: key players, oncogenic drivers, and cancer therapy ENSG00000143147 ENSG00000173040 ENSG00000166813 ENSG00000148384 ENSG00000128602 ENSG00000113448 PMC2943291__F6 Proposed scheme of the molecular mechanism underlying LPCAT2 activation ENSG00000087253 ENSG00000172936 ENSG00000136869 PMC10838060__F1 Molecular mechanism of the cGAS-STING pathway ENSG00000183735 ENSG00000239732 ENSG00000167323 ENSG00000119401 ENSG00000163565 ENSG00000136869 ENSG00000131323 ENSG00000169871 ENSG00000175104 PMC3205057__F6 Influence of miR-300 on apoptosis pathway ENSG00000002330 ENSG00000102871 ENSG00000168040 ENSG00000026103 PMC3205057__F8 Effect of miRNAs on cell cycle, proliferation, and differentiation ENSG00000103479 ENSG00000112242 ENSG00000178999 ENSG00000170989 ENSG00000277273 ENSG00000140299 ENSG00000130508 ENSG00000118971 ENSG00000174607 ENSG00000155363 ENSG00000132341 ENSG00000137801 PMC5347721__F1 Hormonal receptors in lung adenocarcinoma: expression and difference in outcome by sex ENSG00000291971 PMC6089764__F3 Interaction network of paeonol and known gastric cancer genes ENSG00000003056 ENSG00000104689 ENSG00000043462 ENSG00000073756 ENSG00000046604 ENSG00000164305 ENSG00000064300 ENSG00000079112 ENSG00000040608 ENSG00000103546 ENSG00000125538 ENSG00000169429 ENSG00000001626 ENSG00000112115 ENSG00000162692 ENSG00000256713 ENSG00000064012 ENSG00000060140 PMC6854620__F7 Running young is more effective than running at midlife ENSG00000148400 ENSG00000157227 ENSG00000130702 ENSG00000112715 ENSG00000172037 PMC3901350__F1 Noncoding RNAs in DNA Repair and Genome Integrity ENSG00000143799 ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000163961 ENSG00000112130 PMC6370266__F1 LPS-TLR4 activates the NFKB signaling pathway ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC4317864__F5 Schematic representation of the mechanism for UCA1-regulated metabolic switch ENSG00000198793 ENSG00000168610 ENSG00000159399 PMC4048575__F5 Oxidative Stress, Redox Signaling, and Autophagy: Cell Death Versus Survival ENSG00000178573 ENSG00000079999 PMC7801696__F6 LncRNA linc00312 suppresses radiotherapy resistance by targeting DNA-PKcs and impairing DNA damage repair in nasopharyngeal carcinoma ENSG00000149311 ENSG00000164053 ENSG00000146648 PMC4048575__F1 Oxidative Stress, Redox Signaling, and Autophagy: Cell Death Versus Survival ENSG00000152348 ENSG00000123395 ENSG00000198382 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC11053886__F2 Signaling related to flowering ENSG00000163435 ENSG00000102034 ENSG00000203783 ENSG00000131188 PMC8201163__F1 Natural Polyphenols in Metabolic Syndrome: Protective Mechanisms and Clinical Applications ENSG00000169047 ENSG00000113161 ENSG00000169710 ENSG00000136869 PMC9700203__F7 Chromosome-level genome assembly for Dracaena cochinchinensis reveals the molecular basis of its longevity and formation of dragon’s blood ENSG00000105227 PMC5364265__F8 Putative transcription factor network for estrogen signaling ENSG00000087510 ENSG00000165891 ENSG00000205250 PMC9353721__F4 Analysis of Protein–Protein Interactions Identifies NECTIN2 as a Target of N,N-Bis (5-Ethyl-2-hydroxybenzyl) Methylamine for Inhibition of Lung Cancer Metastasis ENSG00000087095 ENSG00000171105 ENSG00000070831 ENSG00000010810 ENSG00000136153 ENSG00000171540 PMC7654589__F2 Canonical PINK1/PARKIN pathway ENSG00000175193 ENSG00000158828 ENSG00000165280 PMC4012261__F6 Graphical representation of the genomic neighborhoods of SRF and ZNF350 ENSG00000101265 ENSG00000111344 ENSG00000113140 ENSG00000187634 ENSG00000165244 ENSG00000256683 ENSG00000072195 ENSG00000197702 ENSG00000089159 ENSG00000149311 ENSG00000175054 ENSG00000197956 ENSG00000115956 ENSG00000261150 ENSG00000118495 ENSG00000084676 ENSG00000116132 ENSG00000185591 ENSG00000080709 ENSG00000122971 PMC3094296__F1 KEGG pathways used for the influence approach ENSG00000174125 ENSG00000169248 ENSG00000081041 ENSG00000163739 ENSG00000124875 ENSG00000273686 ENSG00000169245 ENSG00000186810 ENSG00000183735 ENSG00000115415 ENSG00000138755 ENSG00000125538 ENSG00000163734 ENSG00000131323 ENSG00000164342 PMC7375892__F5 Affected Local Networks by RB1 and TP53 Inactivation Events ENSG00000152240 ENSG00000131462 ENSG00000178999 ENSG00000167513 ENSG00000159259 ENSG00000163918 ENSG00000170606 ENSG00000112118 ENSG00000073111 ENSG00000198056 ENSG00000076003 ENSG00000124762 ENSG00000012048 ENSG00000101868 ENSG00000144554 ENSG00000162607 ENSG00000139687 ENSG00000136982 ENSG00000101109 ENSG00000148400 ENSG00000161970 ENSG00000158169 ENSG00000117399 ENSG00000288210 ENSG00000134574 ENSG00000122952 ENSG00000198176 ENSG00000156970 ENSG00000132646 ENSG00000146648 ENSG00000291603 ENSG00000291971 ENSG00000196591 ENSG00000087586 ENSG00000166851 ENSG00000010671 ENSG00000112312 ENSG00000132383 ENSG00000123374 ENSG00000051180 ENSG00000177084 ENSG00000134690 ENSG00000026103 ENSG00000115163 ENSG00000081237 ENSG00000088305 ENSG00000101057 ENSG00000143933 ENSG00000143228 ENSG00000198901 ENSG00000113328 ENSG00000281614 ENSG00000134057 ENSG00000197299 ENSG00000149554 ENSG00000288325 ENSG00000095002 ENSG00000175305 PMC4868692__F8 Triptolide induces protective autophagy through activation of the CaMKKBeta-AMPK signaling pathway in prostate cancer cells ENSG00000177169 ENSG00000198793 ENSG00000057663 PMC6694711__F2 Renin-angiotensin system and its bypass loops and converging signaling pathways can be targeted at different points ENSG00000168036 PMC7310559__F8 CYT997-induced apoptosis in GC cells ENSG00000168610 PMC10495336__F6 Working model of the oncogenic potential of SGG UCN34 ENSG00000162493 ENSG00000198793 ENSG00000134853 ENSG00000174059 ENSG00000146648 PMC3132641__F3 Proposed mechanisms mediating the effect of the (pro)renin receptor (PRR) in metanephric kidney development ENSG00000162337 ENSG00000188404 ENSG00000168036 ENSG00000146648 PMC6738049__F1 Illustration summarising the major tumour procoagulant effects in pancreatic cancer ENSG00000003436 ENSG00000162493 ENSG00000173083 PMC6738049__F2 Haemostasis and fibrinolysis ENSG00000003436 ENSG00000167653 ENSG00000122194 PMC8833084__F5 Combined Proteomic and Metabolomic Strategy for Allergens Characterization in Natural and Fermented Brassica napus Bee Pollen ENSG00000130957 PMC10383317__F3 Neuroendocrine Effects on the Risk of Metabolic Syndrome in Children ENSG00000178188 ENSG00000112246 ENSG00000121853 PMC7674197__F1 TLR signaling and the endogenous DAMP pathway in systemic JIA and AOSD ENSG00000162711 ENSG00000143546 ENSG00000163220 ENSG00000125538 ENSG00000134070 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC8636938__F2 Emerging Roles on Immunological Effect of Indoleamine 2,3-Dioxygenase in Liver Injuries ENSG00000198793 ENSG00000106546 PMC7522371__F4 TGFB signaling pathway PMC6803483__F1 Metabolic pathway of linoleic and arachidonic acid ENSG00000226275 ENSG00000198670 PMC5520901__F8 UCNPs-Ce6-mediated PDT and the mechanism of autophagy.Notes: UCNPs-Ce6-mediated PDT exhibits an autophagic response through the PI3K/Akt/mTOR signaling pathway that is regulated by ROS, which causes the ABCA1-dependent cholesterol efflux ENSG00000198793 PMC3603396__F3 Altered colonic metabolites during conventionalisation ENSG00000069482 ENSG00000145982 ENSG00000084110 ENSG00000007908 ENSG00000197121 ENSG00000070669 ENSG00000084774 ENSG00000132341 ENSG00000119125 PMC6678174__F1 Mitophagy pathways ENSG00000166233 ENSG00000123240 ENSG00000158828 ENSG00000069509 PMC2929604__F1 Role of TLR4 in hepatic I/R injury ENSG00000169245 ENSG00000172005 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000125347 PMC9704080__F8 13-Acetoxysarcocrassolide induces apoptosis in human hepatocellular carcinoma cells through mitochondrial dysfunction and suppression of the PI3K/AKT/mTOR/p70S6K signalling pathway ENSG00000002330 ENSG00000198793 PMC3064322__F5 Model showing the regulation of PPARA by metabolism and PAR bZip transcription factors ENSG00000169710 PMC8825381__F1 Progression and metastasis of small cell lung carcinoma: the role of the PI3K/Akt/mTOR pathway and metabolic alterations ENSG00000131473 ENSG00000173599 ENSG00000136997 ENSG00000115419 PMC5482641__F3 Collagen type IV alpha 1 (COL4A1) and collagen type XIII alpha 1 (COL13A1) produced in cancer cells promote tumor budding at the invasion front in human urothelial carcinoma of the bladder ENSG00000245848 ENSG00000274619 ENSG00000188910 ENSG00000170365 ENSG00000105612 ENSG00000292234 ENSG00000163131 ENSG00000164647 ENSG00000185885 ENSG00000164120 ENSG00000276561 ENSG00000149418 PMC2790273__F1 Possible cross-talk between Nod2, TCR, Cd28, TLR and TNFR family members in regulating NFKB ENSG00000104856 ENSG00000167207 ENSG00000173039 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC12068849__F1 Canonical and non-canonical signaling pathways ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000134982 ENSG00000168036 PMC12068849__F2 Wnt/Beta-catenin pathway activation and inhibition ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000196839 ENSG00000168036 PMC12068849__F3 Wnt signaling within the breast cancer TME ENSG00000004975 ENSG00000177575 ENSG00000124766 ENSG00000129226 ENSG00000110651 ENSG00000168036 ENSG00000173208 ENSG00000049768 ENSG00000112715 ENSG00000196628 ENSG00000108691 ENSG00000050165 ENSG00000133961 PMC5437112__F1 Illustration of autocrine and paracrine signaling pathways in colorectal cancer ENSG00000281324 ENSG00000114113 ENSG00000157764 ENSG00000134982 ENSG00000107854 ENSG00000168036 ENSG00000164690 ENSG00000128602 ENSG00000168646 PMC10777970__F7 Hedgehog (Hh) signaling pathway ENSG00000128602 PMC4747347__F2 Deconvoluting the complexity of autophagy and Parkinson's disease for potential therapeutic purpose ENSG00000177169 ENSG00000152348 ENSG00000083290 ENSG00000198793 ENSG00000144848 ENSG00000158828 ENSG00000145782 ENSG00000057663 PMC5932548__F4 miRNAs in renal fibrosis PMC5932548__F3 Signalling pathways initiated by miRNAs and TGFB in diabetic nephropathy ENSG00000149269 PMC2254980__F3 Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice ENSG00000157184 ENSG00000042832 ENSG00000170522 ENSG00000198670 ENSG00000026103 PMC2254980__F4 Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice ENSG00000042832 ENSG00000170522 ENSG00000026103 PMC6442448__F2 Target-pathway network ENSG00000150594 ENSG00000171105 ENSG00000050628 ENSG00000198793 ENSG00000172572 ENSG00000173039 ENSG00000007908 ENSG00000158517 ENSG00000145386 ENSG00000112715 ENSG00000073756 ENSG00000164305 ENSG00000102468 ENSG00000007171 ENSG00000132170 ENSG00000108691 ENSG00000111537 ENSG00000149968 ENSG00000102245 ENSG00000128052 ENSG00000095303 ENSG00000100985 ENSG00000120251 ENSG00000146648 PMC10037992__F4 Fasting: From Physiology to Pathology ENSG00000009709 ENSG00000198793 ENSG00000139515 PMC6442448__F1 Compound-target network ENSG00000172572 ENSG00000148344 ENSG00000171791 ENSG00000145386 ENSG00000112715 ENSG00000118777 ENSG00000178726 ENSG00000104368 ENSG00000126218 ENSG00000117525 ENSG00000149968 ENSG00000113520 ENSG00000120251 ENSG00000087245 ENSG00000171105 ENSG00000150594 ENSG00000197635 ENSG00000050628 ENSG00000173039 ENSG00000007908 ENSG00000073756 ENSG00000132693 ENSG00000102468 ENSG00000007171 ENSG00000108691 ENSG00000111537 ENSG00000102245 ENSG00000057593 ENSG00000100985 ENSG00000005381 ENSG00000146648 PMC8993538__F12 Optophysiology: Illuminating cell physiology with optogenetics ENSG00000168610 ENSG00000146648 PMC1450137__F4 Proposed mechanisms underlying the control of Mesp2 expression ENSG00000168214 ENSG00000188095 ENSG00000149922 PMC12027300__F2 Influenza viral suppression of the host immune response by upregulating cellular proteins ENSG00000063176 ENSG00000088888 ENSG00000159216 ENSG00000187605 ENSG00000105397 ENSG00000115415 ENSG00000185436 ENSG00000276051 ENSG00000146648 ENSG00000276561 ENSG00000142166 PMC12027300__F4 Upregulation of cellular proteins that control influenza viral pathogenicity ENSG00000164932 ENSG00000126562 ENSG00000099985 ENSG00000172936 ENSG00000136869 ENSG00000185591 ENSG00000121966 PMC5369369__F55 Gene and protein expressions and metabolomics exhibit activated redox signaling and wnt/Beta-catenin pathway are associated with metabolite dysfunction in patients with chronic kidney disease ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000154059 ENSG00000168036 ENSG00000079999 PMC8387187__F8 Leptin Induced TLR4 Expression via the JAK2-STAT3 Pathway in Obesity-Related Osteoarthritis ENSG00000170458 ENSG00000168610 PMC3167888__F6 Cytolethal distending toxin: a conserved bacterial genotoxin that blocks cell cycle progression, leading to apoptosis of a broad range of mammalian cell lineages ENSG00000149311 ENSG00000120868 ENSG00000171791 PMC8509806__F6 Anti-Hepatocellular Carcinoma Biomolecules: Molecular Targets Insights ENSG00000135446 PMC5085687__F5 Molecular mechanisms of osteoporosis in ACTH-secreting pituitary adenomas ENSG00000118785 ENSG00000177606 ENSG00000132478 ENSG00000154188 ENSG00000131196 ENSG00000166033 PMC11943880__F2 Physiological effects of KYN pathway metabolites ENSG00000165556 ENSG00000183735 ENSG00000164430 ENSG00000293532 ENSG00000106546 PMC8139196__F2 Delineating the Role of Mitophagy Inducers for Alzheimer Disease Patients ENSG00000143799 ENSG00000177169 ENSG00000162711 ENSG00000183735 ENSG00000077463 ENSG00000096717 ENSG00000142082 PMC2727567__F1 Unwelcome Complement ENSG00000009724 ENSG00000291559 ENSG00000244731 PMC7070965__F7 EDG and DC on FcERI-mediated signaling pathway in KU812F cells ENSG00000213658 PMC11943880__F1 Kynurenine pathway ENSG00000162882 ENSG00000183077 PMC12068849__F4 Interaction between the Wnt signaling pathway and other pathways in the breast cancer TME ENSG00000162552 ENSG00000154342 ENSG00000281324 ENSG00000137273 ENSG00000162337 ENSG00000134982 ENSG00000188064 ENSG00000198793 ENSG00000168036 ENSG00000103241 ENSG00000104332 ENSG00000078579 ENSG00000166813 ENSG00000156427 ENSG00000134245 ENSG00000164690 ENSG00000128602 PMC4175047__F9 Proposed mechanisms by which miR-34a regulates mesangial cell proliferation ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC6737211__F5 Activation of Ser/Gly synthesis from glucose, their efficient incorporation into purines, and reverse flux of the Ser–Gly one-carbon pathway underlie preference for glucose as substrate for purine synthesis in lung cancer tissues ex vivo ENSG00000284320 ENSG00000065911 ENSG00000100714 ENSG00000092621 ENSG00000163738 ENSG00000178445 ENSG00000120254 PMC5623591__F3 Central tolerance for B cells ENSG00000177455 ENSG00000095585 ENSG00000105369 ENSG00000171105 ENSG00000167323 ENSG00000007312 ENSG00000150907 ENSG00000186716 ENSG00000136997 ENSG00000197943 ENSG00000010671 PMC4891409__F1 MiRs and their targets in signaling pathway of LSCC ENSG00000132906 ENSG00000145632 ENSG00000019991 ENSG00000213928 ENSG00000134982 ENSG00000005882 ENSG00000020633 ENSG00000168036 ENSG00000109586 ENSG00000168610 ENSG00000145604 ENSG00000115415 ENSG00000096717 ENSG00000140443 PMC8214167__F6 Innate immune response analysis in COVID-19 and kawasaki disease reveals MIS-C predictors ENSG00000162711 ENSG00000183735 ENSG00000115415 ENSG00000163565 ENSG00000172936 ENSG00000168610 ENSG00000276561 ENSG00000184216 ENSG00000086544 ENSG00000164342 ENSG00000142166 PMC8945019__F5 Immunosuppressive Signaling Pathways as Targeted Cancer Therapies ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC4673190__F1 The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer ENSG00000149311 ENSG00000175054 PMC6981480__F1 ER-stress induced UPR signaling ENSG00000128272 ENSG00000144895 PMC3135180__F3 Convergent stem cell regulatory networks control expression of key stem cell genes ENSG00000138795 PMC3234195__F1 Petroleum diesel, biodiesel, and ethanol ENSG00000173599 ENSG00000198670 PMC10745821__F9 Proposed model of the signaling pathway induced by the CSHE treatment ENSG00000150907 ENSG00000161533 ENSG00000169710 PMC8599200__F6 Normal and Premature Adrenarche ENSG00000151632 ENSG00000198610 ENSG00000127948 ENSG00000187134 PMC8715300__F12 Cannabinoid control of gingival immune activation in chronically SIV-infected rhesus macaques involves modulation of the indoleamine-2,3-dioxygenase-1 pathway and salivary microbiome ENSG00000169245 ENSG00000262406 ENSG00000137857 ENSG00000134762 PMC10578286__F1 Insulin signaling pathway schematic ENSG00000169047 PMC4872805__F2 Sirtuins as regulators of metabolism and healthspan ENSG00000139180 ENSG00000150907 ENSG00000175567 ENSG00000096717 ENSG00000142082 ENSG00000160741 ENSG00000106459 PMC4872805__F3 Sirtuins as regulators of metabolism and healthspan ENSG00000150907 ENSG00000175567 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000089163 ENSG00000160741 ENSG00000283100 PMC11395051__F7 The results and the proposed mechanisms of action of the examined proteins and signaling pathways in HEC-1A cells ENSG00000087245 ENSG00000168329 ENSG00000164736 ENSG00000138798 ENSG00000128342 ENSG00000100985 ENSG00000168610 ENSG00000146648 PMC4872805__F1 Sirtuins as regulators of metabolism and healthspan ENSG00000150907 ENSG00000291803 ENSG00000096717 PMC2739389__F2 Malignant Melanoma in the 21st Century: The Emerging Molecular Landscape ENSG00000019991 ENSG00000157764 ENSG00000135446 ENSG00000150907 ENSG00000198793 ENSG00000105810 ENSG00000140443 PMC4765871__F8 Refined subnetwork using reconstructed pseudo time-series data (left) compared with experimental validated network in () (right) ENSG00000162676 ENSG00000165702 ENSG00000179348 PMC3632131__F1 Shared network structure by non-small lung cancer pathway in KEGG and reconstructed co-expression networks using the CCA and GLASSO methods ENSG00000132906 ENSG00000002330 ENSG00000138798 ENSG00000115904 ENSG00000100485 ENSG00000068028 ENSG00000117020 ENSG00000112242 ENSG00000163235 ENSG00000166501 ENSG00000197943 ENSG00000139687 ENSG00000282899 PMC3323563__F8 Activation of Cell Cycle Arrest and Apoptosis by the Proto-Oncogene Pim-2 ENSG00000123374 ENSG00000120868 PMC7279704__F1 Simplified representation of mechanisms of DDR and DNA repair ENSG00000012048 ENSG00000175054 ENSG00000083093 ENSG00000108582 ENSG00000079246 ENSG00000164362 ENSG00000051180 ENSG00000138385 ENSG00000139618 PMC3438135__F1 Altered pancreatic beta cell mechanism silencing alpha and delta cells ENSG00000124102 ENSG00000168803 PMC6416708__F1 Triglyceride-rich lipoprotein metabolism and mechanism of atherosclerosis ENSG00000167772 ENSG00000130164 ENSG00000132855 PMC2739389__F3 Malignant Melanoma in the 21st Century: The Emerging Molecular Landscape ENSG00000132906 ENSG00000002330 ENSG00000120868 ENSG00000171791 ENSG00000168040 ENSG00000064012 ENSG00000164305 ENSG00000084774 ENSG00000026103 PMC9169370__F2 Pyroptosis in inflammatory diseases and cancer ENSG00000278718 ENSG00000162711 ENSG00000124256 ENSG00000137275 ENSG00000138794 ENSG00000163568 ENSG00000091592 ENSG00000091106 ENSG00000168040 ENSG00000147697 ENSG00000073605 ENSG00000145649 ENSG00000064012 ENSG00000285379 PMC10987323__F7 MtETC in regulating bacterial infection ENSG00000162711 ENSG00000166278 PMC8116547__F1 miRNAs and Leukotrienes in Respiratory Syncytial Virus Infection ENSG00000226275 PMC6749033__F2 Metabolic regulation of pleotropic autophagy ENSG00000177169 ENSG00000114388 ENSG00000205629 PMC10987323__F9 MtETC in M1 macrophage polarization ENSG00000131473 ENSG00000079432 PMC7204879__F4 HCoV-host interaction ENSG00000128272 ENSG00000144895 ENSG00000102007 ENSG00000171791 PMC10151377__F3 Insights into the pharmacological and therapeutic effects of apigenin in liver injuries and diseases ENSG00000148926 ENSG00000168036 PMC7654518__F3 Molecular mechanisms of SGLT2 inhibitors on iron homeostasis, mitochondrial function, and cardiac microvasculature in diabetic cardiomyopathy ENSG00000116688 ENSG00000171109 ENSG00000214253 PMC9467784__F2 Targeting Strategies for Aberrant Lipid Metabolism Reprogramming and the Immune Microenvironment in Esophageal Cancer: A Review ENSG00000134982 ENSG00000198793 ENSG00000169710 ENSG00000136869 ENSG00000168610 ENSG00000146648 PMC5706744__F1 Mammalian biogenic polyamines and metabolic pathways ENSG00000095059 ENSG00000148832 ENSG00000288145 ENSG00000104904 ENSG00000129932 ENSG00000128602 ENSG00000116649 ENSG00000102172 PMC4307161__F16 The Therapeutic Potential of Cystathionine Beta-Synthetase/Hydrogen Sulfide Inhibition in Cancer ENSG00000125166 PMC3250173__F7 TLR3/TLR4-mediated signaling pathways ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000164342 PMC6844216__F1 Different death mechanisms of liver cells are involved in the pathogenesis of liver injury induced by MNPs ENSG00000278718 ENSG00000102871 ENSG00000198793 PMC12207208__F3 TREM2 activation and downstream signaling TREM2 binds to ligands such as AB, ApoE, HDL, and LDL, leading to its activation ENSG00000011600 PMC6510993__F8 Model of GQ folding within the actively extending telomerase complex ENSG00000166340 ENSG00000164362 ENSG00000128513 PMC5595712__F3 A maize amino acids network involving key genes identified in this study by GWAS ENSG00000069482 ENSG00000053438 ENSG00000128928 PMC5559637__F5 H. pylori cag-T4SS-dependent, NFKB-driven innate immune response in gastric epithelial cells ENSG00000073331 ENSG00000145365 ENSG00000175104 ENSG00000106100 PMC6480367__F1 Rapamycin (mTOR) signaling pathway ENSG00000101407 ENSG00000155792 PMC2561962__F1 Ischemia induces cell death by several distinct pathways, and Hsp70 reduces all of these ENSG00000132906 ENSG00000120868 ENSG00000026103 PMC2775177__F1 Branches of the UPR signalling pathway ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC11012680__F2 Synthetic Routes and Clinical Application of Representative Small-Molecule EGFR Inhibitors for Cancer Therapy ENSG00000291971 ENSG00000146648 PMC5301276__F2 Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases ENSG00000109452 ENSG00000117020 PMC8906189__F4 The Coagulation Pathways Leading to the Formation of D-Dimer During Blood-Brain Barrier Disruption ENSG00000160752 ENSG00000134982 ENSG00000122194 PMC10838060__F10 CGAS-STING by metal ions ENSG00000162711 ENSG00000164430 ENSG00000167323 PMC7838386__F3 Extracellular factors govern dendritic morphogenesis via convergent signaling ENSG00000145826 PMC8883286__F3 Mechanisms Underlying Influence of Bioelectricity in Development ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC5420432__F1 mTOR signaling pathway in podocyte autophagy ENSG00000008710 ENSG00000198793 PMC8600424__F1 New insights into Epstein-Barr virus-associated tumors: Exosomes ENSG00000074319 ENSG00000135404 ENSG00000127191 PMC7827772__F3 Calreticulin (CRT) exposure in the response to immunogenic cell death (ICD) inducers PMC11397228__F4 Impact of BPs on metabolic disease treatment via gut microbiota modulation ENSG00000042832 ENSG00000169710 ENSG00000172936 ENSG00000136869 ENSG00000131096 PMC5527946__F1 Regulation of autophagy ENSG00000198382 ENSG00000171791 PMC1854955__F7 Schematic depiction of the molecular mechanism for the progression from HPS to chronic active disease or T-cell lymphoma in EBV-infected T cells ENSG00000102871 ENSG00000082512 ENSG00000168040 ENSG00000127191 PMC5310163__F7 Interaction of lactobacilli with transformed cells ENSG00000005381 ENSG00000167419 PMC6306440__F1 Abnormalities in the DNA damage repair pathway in T cells of rheumatoid arthritis patients ENSG00000149311 ENSG00000175054 PMC7442613__F1 Topical treatment strategies to manipulate human skin pigmentation ENSG00000115138 ENSG00000080166 ENSG00000107165 PMC5932357__F2 Antimicrobial autophagy is inhibited in Mycobacterium leprae infections through the activation of the type I interferon (IFN) pathway ENSG00000183735 ENSG00000123576 ENSG00000164430 ENSG00000135114 PMC8995529__F5 Tanshinone Ameliorates Glucocorticoid-Induced Bone Loss via Activation of AKT1 Signaling Pathway ENSG00000023445 ENSG00000110330 ENSG00000179091 ENSG00000135446 ENSG00000132646 ENSG00000198793 ENSG00000123374 ENSG00000105810 ENSG00000164305 ENSG00000139687 ENSG00000124762 PMC6966636__F9 HMGCS2-mediated ketogenesis impacts liver cancer progression and treatment ENSG00000170558 PMC8995529__F1 Tanshinone Ameliorates Glucocorticoid-Induced Bone Loss via Activation of AKT1 Signaling Pathway ENSG00000023445 ENSG00000110330 ENSG00000165841 ENSG00000135446 ENSG00000132646 ENSG00000140505 ENSG00000123374 ENSG00000105810 ENSG00000140465 ENSG00000164305 ENSG00000139687 ENSG00000124762 PMC7179138__F5 Schematic diagram illustrating the mechanisms of A ENSG00000002330 ENSG00000102871 ENSG00000168040 PMC4393010__F12 Pathway regulation by CsrA ENSG00000159224 ENSG00000197713 ENSG00000122966 ENSG00000172005 ENSG00000062485 PMC7998903__F5 Involvements of the studied neurotransmitters in tumor development ENSG00000198793 ENSG00000149295 ENSG00000132359 PMC3205804__F2 From a physiological point of view, exfoliated epithelial cells resulting from nutritional induction or mild stress are in anoikis by activating a survival mechanism partly using the molecular paths of macroautophagy ENSG00000169047 ENSG00000198793 ENSG00000154059 PMC6966539__F2 p53 control of cellular metabolism ENSG00000180210 ENSG00000005882 ENSG00000078237 ENSG00000284194 PMC4014913__F2 Metabolic pathways of fatty acid (FA) and triacylglycerol (TAG) synthesis, and mechanisms by which lipid intermediates affect hepatic insulin sensitivity ENSG00000170522 ENSG00000169047 ENSG00000198793 ENSG00000198670 ENSG00000026103 PMC6966539__F3 Dual effect of p53 on autophagy ENSG00000177169 ENSG00000198793 ENSG00000158828 PMC10604560__F3 Lipid metabolism ENSG00000131473 ENSG00000135218 ENSG00000042832 ENSG00000170522 ENSG00000169710 ENSG00000198670 PMC4726449__F5 Identification of Symptomatic Fetuses Infected with Cytomegalovirus Using Amniotic Fluid Peptide Biomarkers ENSG00000164879 ENSG00000172005 ENSG00000273686 ENSG00000076003 PMC8868324__F7 Protective Effect of GIP against Monosodium Glutamate-Induced Ferroptosis in Mouse Hippocampal HT-22 Cells through the MAPK Signaling Pathway ENSG00000159224 ENSG00000167468 PMC5440785__F2 Schematic representation of the contribution of ER stress to the development of atherosclerosis
protein 1 ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC6589170__F1 NLRP3 inflammasome pathway ENSG00000162711 ENSG00000172936 ENSG00000136869 PMC8035014__F8 Immune regulatory activity of TCM formula ZQT in TME ENSG00000111537 ENSG00000112699 ENSG00000168610 PMC4026543__F2 EPH receptors crosstalk with EMT-related signaling pathways ENSG00000196411 ENSG00000142627 ENSG00000168036 ENSG00000182580 PMC8684645__F2 NK cell upraise in the dark world of cancer stem cells ENSG00000111537 ENSG00000139187 ENSG00000164136 ENSG00000174059 PMC6126141__F1 Schwann cell Myc-interacting zinc-finger protein 1 without pox virus and zinc finger: epigenetic implications in a peripheral neuropathy ENSG00000115548 ENSG00000065833 ENSG00000114113 ENSG00000122877 ENSG00000196591 ENSG00000164690 ENSG00000132510 ENSG00000100146 ENSG00000107077 PMC9034918__F6 Screening Potential Drugs for the Development of NAFLD Based on Drug Perturbation Gene Set ENSG00000142192 PMC7862630__F3 Deubiquitylases in developmental ubiquitin signaling and congenital diseases ENSG00000135655 ENSG00000124422 ENSG00000163930 ENSG00000291527 ENSG00000162607 ENSG00000292211 ENSG00000162601 ENSG00000134588 ENSG00000143258 ENSG00000136014 PMC9550461__F4 Endogenous Vasoactive Peptides and Vascular Aging-Related Diseases ENSG00000132329 ENSG00000291971 ENSG00000086991 ENSG00000168610 ENSG00000146648 PMC5285405__F3 Viruses exploit host proteasome pathway for immune evasion ENSG00000067066 ENSG00000163565 ENSG00000172005 ENSG00000173039 ENSG00000172936 ENSG00000276561 ENSG00000140464 PMC8324245__F7 Ovine CD14- an Immune Response Gene Has a Role Against Gastrointestinal Nematode Haemonchus contortus—A Novel Report ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000172936 ENSG00000131323 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 ENSG00000143387 PMC5285405__F5 Viral regulation of host proteins via post translational modifications ENSG00000171720 ENSG00000173039 ENSG00000146648 ENSG00000140464 PMC9256444__F6 Cancer Stem Cells: From an Insight into the Basics to Recent Advances and Therapeutic Targeting ENSG00000198793 PMC9256444__F5 Cancer Stem Cells: From an Insight into the Basics to Recent Advances and Therapeutic Targeting ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000128602 PMC8469761__F1 Glycosylation in Vascular Calcification ENSG00000118972 ENSG00000170365 ENSG00000198793 ENSG00000168036 PMC9256444__F2 Cancer Stem Cells: From an Insight into the Basics to Recent Advances and Therapeutic Targeting ENSG00000178860 ENSG00000019991 ENSG00000087245 ENSG00000107562 ENSG00000041982 ENSG00000149968 ENSG00000163235 ENSG00000100985 ENSG00000112715 PMC12166595__F2 The Notch signalling pathway and conservation of its components across metazoan lineages ENSG00000140564 ENSG00000069869 ENSG00000224470 ENSG00000133961 ENSG00000137845 PMC8511326__F4 Transcriptome Profiling Reveals Important Transcription Factors and Biological Processes in Skin Regeneration Mediated by Mechanical Stretch ENSG00000070388 ENSG00000005981 ENSG00000169006 ENSG00000172548 ENSG00000161664 ENSG00000130528 ENSG00000167768 ENSG00000163833 ENSG00000182177 ENSG00000109906 ENSG00000239388 ENSG00000137563 ENSG00000096006 ENSG00000133019 ENSG00000288250 ENSG00000136842 ENSG00000215853 ENSG00000068976 ENSG00000152592 ENSG00000185269 ENSG00000278693 ENSG00000118972 ENSG00000204020 ENSG00000121552 ENSG00000183763 ENSG00000081041 ENSG00000181408 ENSG00000285348 ENSG00000140416 ENSG00000154227 ENSG00000158022 ENSG00000072401 ENSG00000154415 ENSG00000101188 ENSG00000102893 ENSG00000136160 ENSG00000137675 ENSG00000115461 ENSG00000143184 ENSG00000067177 PMC6561926__F9 Schematic depiction of lncRNA-p21/EZH2/STAT3 pathway ENSG00000168610 PMC8801635__F12 Protective effect of baicalin against arsenic trioxide-induced acute hepatic injury in mice through JAK2/STAT3 signaling pathway ENSG00000168610 ENSG00000163631 PMC2697619__F5 Proposed signaling pathways by which the Tec kinases regulate JNK activation, actin polymerization, and cytokine expression in LPS-stimulated neutrophils ENSG00000070831 ENSG00000170458 ENSG00000125538 ENSG00000136869 ENSG00000135605 PMC6982012__F2 Conversion into myofibroblasts from quiescent fibroblast involves mechanical and paracrine activation of profibrotic pathways PMC3342643__F3 Diacylglycerol kinases in immune cell function and self-tolerance ENSG00000124181 PMC6337644__F3 Telomeres are cap-like features at the ends of chromosomes that help protect them when cells divide ENSG00000062485 PMC7472989__F1 Classical neuroimmune network ENSG00000111537 ENSG00000125538 ENSG00000145321 PMC8764250__F3 Interleukin 27 Signaling in Rheumatoid Arthritis Patients: Good or Evil? ENSG00000105397 ENSG00000115415 ENSG00000107485 PMC7653026__F3 NFKB inflammation signaling pathway diagram ENSG00000174125 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC9359100__F7 Mfn2 is responsible for inhibition of the RIG-I/IRF7 pathway and activation of NLRP3 inflammasome in Seneca Valley virus-infected PK-15 cells to promote viral replication ENSG00000162711 ENSG00000116688 ENSG00000276561 PMC7246618__F1 Monoubiquitination in human diseases ENSG00000110395 ENSG00000144554 ENSG00000078747 ENSG00000132646 ENSG00000115392 ENSG00000077721 ENSG00000162607 ENSG00000146648 PMC11241178__F8 Target pathway analysis of cordycepin combined with doxorubicin against breast cancer ENSG00000108691 ENSG00000149968 ENSG00000109320 ENSG00000078747 ENSG00000102871 ENSG00000163739 ENSG00000100985 ENSG00000135341 ENSG00000064012 ENSG00000164305 PMC8584933__F1 Genome-Wide Analysis of Alternative Splicing and Non-Coding RNAs Reveal Complicated Transcriptional Regulation in Cannabis sativa L. ENSG00000197429 PMC2937452__F1 Model of pyrimidine synthesis and salvage pathways in Toxoplasma gondii ENSG00000094841 ENSG00000102967 ENSG00000254550 PMC10761042__F8 PTP1B-Cdk3 Signaling Axis Promotes Cell Cycle Progression of Human Glioblastoma Cells through an Rb-E2F Dependent Pathway ENSG00000250506 PMC10506040__F2 Schematic representation showing downstream signaling events in cross-talk between adiponectin signal transduction and insulin signaling pathway[67] ENSG00000157500 ENSG00000169047 ENSG00000159346 ENSG00000285070 PMC12091695__F1 Simplified schematic representation of steps linking dyslipidemia with macrophage/microglia induced RNV ENSG00000130164 ENSG00000075239 PMC6953124__F9 Proposed anti-tumor mechanism of rubioncolin C ENSG00000198793 ENSG00000172936 ENSG00000175104 ENSG00000127191 PMC5677515__F3 Significantly Mutated Genes and Regulatory Pathways in SCLC – A Meta-analysis ENSG00000137078 ENSG00000137601 ENSG00000173156 ENSG00000288455 ENSG00000113456 ENSG00000182511 ENSG00000144857 ENSG00000010810 ENSG00000164690 ENSG00000154134 ENSG00000128602 ENSG00000185008 ENSG00000126458 PMC8802069__F9 Activation of Autophagy Through the NLRP3/mTOR Pathway: A Potential Mechanism for Alleviation of Pneumonia by QingFei Yin ENSG00000162711 ENSG00000197471 ENSG00000198793 PMC3725781__F1 Genetic and molecular control of Osterix in skeletal formation ENSG00000125398 ENSG00000100219 ENSG00000108821 PMC3642687__F1 Pathway of reversible protein modification reactions that involve NAD+ consumption ENSG00000133315 ENSG00000172264 ENSG00000227345 PMC3437319__F2 Regulation of mammalian target of rapamycin complex (mTORC) signaling networks ENSG00000169047 PMC5618627__F3 HSP40 family member, DNAJB6a (MRJ), prevents tumor formation through inhibition of the Wnt pathway ENSG00000105993 ENSG00000154342 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000163132 ENSG00000125084 PMC5618627__F2 HSP27 mediated suppression of apoptosis promotes tumorigenesis ENSG00000162889 ENSG00000114738 ENSG00000026103 PMC7403357__F3 Bioinformatics analysis of data ENSG00000173821 ENSG00000157404 ENSG00000110492 ENSG00000109906 ENSG00000170298 ENSG00000187764 ENSG00000171388 ENSG00000149781 ENSG00000137496 ENSG00000106631 ENSG00000126218 ENSG00000124479 ENSG00000122691 ENSG00000163421 ENSG00000188404 ENSG00000166501 ENSG00000164400 ENSG00000122862 ENSG00000140464 ENSG00000026103 ENSG00000259207 ENSG00000169896 ENSG00000114346 ENSG00000148848 ENSG00000117322 ENSG00000169245 ENSG00000067066 ENSG00000102837 ENSG00000102760 ENSG00000180739 ENSG00000171004 ENSG00000198355 PMC7987459__F2 Molecular pathways affected by Mn porphyrins in normal and cancer cell ENSG00000163131 ENSG00000086991 ENSG00000023909 ENSG00000057663 ENSG00000105227 ENSG00000079999 PMC7881125__F6 Distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma ENSG00000123505 ENSG00000116649 ENSG00000116761 ENSG00000116984 PMC9576726__F7 Effects of MSC-Exos on glycolysis and renal fibrosis ENSG00000178860 ENSG00000135605 ENSG00000152556 PMC11222861__F8 Brief proposal model of altered epigenetic regulation mechanisms of histone H3K27 acetylation causing FLHS and a summarized workflow of comparative analysis of fatty liver disease among different species ENSG00000157404 ENSG00000110244 ENSG00000139269 ENSG00000165072 ENSG00000124253 PMC4150259__F1 An overview of oncogenic KRAS-driven RAF/MEK/ERK and PI3K/PDK1/AKT signalling networks in pancreatic cancer ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC4402634__F3 KEGG pathway map for TGFB and MAPK signaling pathways ENSG00000113558 ENSG00000156574 ENSG00000111816 ENSG00000111962 PMC7501485__F7 Rosuvastatin and simvastatin attenuate cisplatin-induced cardiotoxicity via disruption of endoplasmic reticulum stress-mediated apoptotic death in rats: targeting ER-Chaperone GRP78 and Calpain-1 pathways ENSG00000128272 ENSG00000171791 PMC4402634__F4 KEGG pathway map for complement and coagulation pathway ENSG00000110799 ENSG00000181104 ENSG00000115718 ENSG00000122194 ENSG00000178726 ENSG00000185010 ENSG00000104368 ENSG00000184500 ENSG00000180210 ENSG00000126218 ENSG00000101981 ENSG00000117525 ENSG00000011422 ENSG00000164344 ENSG00000062485 ENSG00000039537 ENSG00000003436 ENSG00000113600 ENSG00000088926 ENSG00000166278 ENSG00000117322 ENSG00000057593 ENSG00000175899 ENSG00000080618 ENSG00000276838 PMC6838686__F2 Systemic Immune Dyshomeostasis Model and Pathways in Alzheimer’s Disease ENSG00000150782 ENSG00000173599 ENSG00000121807 ENSG00000133027 PMC9078761__F7 Network Pharmacology and Molecular Docking-Based Strategy to Investigate the Multitarget Mechanisms of Shenqi Yizhi Granule on Alzheimer's Disease ENSG00000132906 ENSG00000204842 ENSG00000165280 ENSG00000101327 ENSG00000138741 ENSG00000066427 ENSG00000064012 ENSG00000115317 PMC8064375__F4 Persulfidated proteins identified in root tissues involved in autophagy ENSG00000152348 ENSG00000144848 ENSG00000145782 PMC3646067__F1 Proposed scheme linking metabolic and signaling pathways to insulin resistance in the heart ENSG00000135218 ENSG00000042832 ENSG00000169047 ENSG00000198793 PMC3512574__F5 TGFB in Cancer ENSG00000170365 ENSG00000135446 ENSG00000136997 ENSG00000123374 ENSG00000205250 ENSG00000162772 ENSG00000176165 ENSG00000125968 PMC6360516__F7 LIMK2-Mediated Cofilin1 Phosphorylation Signals TGFB1-Induced GC InsensitivityPhospho-cofilin1 is implicated as a key link in the chain of signalling behavior of TGFB1-induced GC insensitivity ENSG00000070831 ENSG00000198670 ENSG00000182541 PMC12248293__F9 BRD4770 attenuating DOX-induced cardiac injury through the Nrf2/ATF4/SLC7A11 pathway ENSG00000128272 ENSG00000151012 ENSG00000167468 PMC6549480__F7 A schematic molecular model for PSMD3 in the stabilization of HER2 ENSG00000108344 ENSG00000101557 PMC5594516__F9 Schematic representation of the proposed mechanism of circLARP4 in GC cells ENSG00000145321 ENSG00000161813 ENSG00000131023 ENSG00000123908 PMC3512574__F3 TGFB in Cancer ENSG00000106683 ENSG00000143768 ENSG00000070831 ENSG00000243709 ENSG00000135409 ENSG00000241186 ENSG00000163914 ENSG00000156574 ENSG00000138071 ENSG00000175104 PMC8258161__F1 Robustifying Experimental Tracer Design for13C-Metabolic Flux Analysis ENSG00000112977 ENSG00000069482 ENSG00000172005 ENSG00000011451 ENSG00000134531 PMC6134143__F5 TNFR2-triggered, necrostatin-1-sensitive TNFR1 signaling ENSG00000137275 ENSG00000125538 ENSG00000056558 ENSG00000168404 ENSG00000127191 ENSG00000064012 ENSG00000285379 PMC5233421__F6 Non-Lethal Endotoxin Injection: A Rat Model of Hypercoagulability ENSG00000261371 ENSG00000162692 ENSG00000135919 PMC1665458__F7 Proteins differentially regulated in RCC involved in carbohydrate metabolism are shown overlaid on the glycolysis and gluconeogenesis pathway KEGG #00010 diagram ENSG00000163541 ENSG00000127884 PMC11173325__F1 The mTOR signaling pathway and the cellular functions driven by the formation of its two main complexes, mTORC1 and mTORC2 ENSG00000101407 ENSG00000169047 ENSG00000118515 ENSG00000155792 PMC11173325__F2 Roles of mTORC1 and mTORC2 in regulating metabolic diseases, cancer, and aging ENSG00000140564 ENSG00000042832 ENSG00000169047 PMC7082927__F1 Molecular pathogenesis of thyroid cancer involves dysregulation of the mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3 kinase (PI3K)/AKT pathways ENSG00000157764 ENSG00000164362 ENSG00000168036 ENSG00000132170 PMC8097461__F6 Metabolic Survival Adaptations of Plasmodium falciparum Exposed to Sublethal Doses of Fosmidomycin ENSG00000122966 ENSG00000288145 ENSG00000172005 ENSG00000197429 PMC7082274__F1 Steroidogenic pathway for aldosterone and the ‘hybrid steroids’—18OH-cortisol and 18-oxocortisol ENSG00000203859 ENSG00000179142 PMC4629494__F1 Pyruvate and octanoate metabolism in the liver ENSG00000122966 ENSG00000173599 ENSG00000062485 PMC7017171__F1 Phosphatidylinositol 3-kinase (PI3K)/AKT/mTOR pathway ENSG00000198793 ENSG00000124253 PMC4023029__F7 Proposed pathway for activation/proliferation of alloantigen-specific nTreg and comparison with the non-antigen driven proliferation of nTreg that do not have a TCR specific for the antigen ENSG00000049768 PMC4775314__F3 Untapped Potential of Tyrosine-based G Protein Signaling ENSG00000090402 ENSG00000136869 ENSG00000168610 PMC8443980__F1 Macrophage and Adipocyte Mitochondrial Dysfunction in Obesity-Induced Metabolic Diseases ENSG00000162711 ENSG00000158828 ENSG00000145782 ENSG00000057663 PMC8122529__F2 Regulatory Role of Nrf2 Signaling Pathway in Wound Healing Process ENSG00000100387 ENSG00000023909 ENSG00000079999 PMC8122529__F3 Regulatory Role of Nrf2 Signaling Pathway in Wound Healing Process ENSG00000100387 ENSG00000023909 ENSG00000079999 PMC3319771__F2 Convergence of miR-21 target genes and the apoptosis pathway ENSG00000136158 ENSG00000002330 ENSG00000164056 ENSG00000102871 ENSG00000120868 ENSG00000168040 ENSG00000095002 ENSG00000132676 ENSG00000026103 PMC7797171__F5 Reversine, a selective MPS1 inhibitor, induced autophagic cell death via diminished glucose uptake and ATP production in cholangiocarcinoma cells ENSG00000134057 ENSG00000291971 ENSG00000185591 PMC6323245__F1 Different stages of erythropoiesis and regulatory processes (including cytokines, transcription factors and related signal transduction proteins) ENSG00000102145 ENSG00000187266 ENSG00000165702 ENSG00000179348 ENSG00000140443 PMC6323245__F2 PI3K/Akt signaling pathway and glucose metabolism (glycolysis, glucose uptake, nitric oxide glucose synthase, apoptosis and cell survival) ENSG00000002330 ENSG00000005882 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC4593336__F1 Canonical Wnt3a pathway ENSG00000154342 ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000026508 ENSG00000168036 ENSG00000196562 PMC7173926__F5 Computational analysis for identification of the extracellular matrix molecules involved in endometrial cancer progression ENSG00000259207 ENSG00000005961 ENSG00000050767 ENSG00000215018 ENSG00000137845 ENSG00000132693 ENSG00000196739 ENSG00000160963 ENSG00000010671 ENSG00000082293 ENSG00000139219 ENSG00000171502 ENSG00000169436 ENSG00000213658 ENSG00000111799 ENSG00000010810 ENSG00000188517 ENSG00000197943 ENSG00000151967 ENSG00000197467 PMC3991963__F1 TGFB2 and Bone Morphogenetic Proteins in the Trabecular Meshwork and Glaucoma ENSG00000049323 ENSG00000170365 ENSG00000115318 ENSG00000138131 ENSG00000134013 ENSG00000134363 ENSG00000168487 ENSG00000137801 PMC7137995__F5 Elucidation of Functional Roles of Sialic Acids in Cancer Migration ENSG00000069482 ENSG00000008513 ENSG00000135454 ENSG00000170266 ENSG00000111728 ENSG00000101638 ENSG00000196743 ENSG00000115525 PMC4898408__F3 Hub-pathway network of GSZD ENSG00000143799 ENSG00000226275 ENSG00000177606 ENSG00000213341 ENSG00000143226 ENSG00000115718 ENSG00000143631 ENSG00000132170 PMC3572738__F4 Cellular iron balance ENSG00000118564 ENSG00000113558 ENSG00000158578 PMC8120506__F2 Mitochondrial biogenesis signaling pathway is a potential therapeutic target for myasthenia gravis via energy metabolism (Review) ENSG00000096717 ENSG00000106459 PMC9588203__F1 Triggering receptor expressed on myeloid cells-1 (TREM-1) in central nervous system diseases ENSG00000291603 PMC8198060__F2 Ubiquitin Proteasome Pathway Transcriptome in Epithelial Ovarian Cancer ENSG00000012048 ENSG00000144554 ENSG00000188827 ENSG00000077152 ENSG00000181544 ENSG00000115392 ENSG00000162607 ENSG00000187741 ENSG00000158169 PMC5629289__F2 IFNA2: The prototypic human alpha interferon ENSG00000213928 ENSG00000105397 ENSG00000115415 PMC7426442__F3 SARS-CoV-mediated evasion of host innate immune response ENSG00000130234 PMC6149701__F1 Dual Regulation of NFKB signaling by SIRT6 ENSG00000145604 ENSG00000101945 ENSG00000077463 PMC6161481__F8 The proposed pathways activated by LPS to modulate mTOR-dependent autophagy and the production of pro-inflammatory cytokines in Caco-2 and HT-29 cells ENSG00000125538 ENSG00000198793 ENSG00000172936 ENSG00000136869 PMC8489073__F6 Oncogenic KRAS blockade therapy: renewed enthusiasm and persistent challenges ENSG00000124216 ENSG00000198793 ENSG00000169047 ENSG00000115904 ENSG00000143622 ENSG00000087586 ENSG00000146648 ENSG00000196712 ENSG00000140443 PMC3341105__F2 Signal transducer and activator of transcription 3 (Stat3) signaling ENSG00000291971 ENSG00000198793 ENSG00000026508 PMC7947625__F1 Mevalonate (MVA) pathway and its connection with the intracellular energy metabolism signaling ENSG00000197429 PMC9367564__F1 Versatile Triad Alliance: Bile Acid, Taurine and Microbiota ENSG00000160867 ENSG00000167910 ENSG00000180432 ENSG00000131096 PMC8683177__F1 Tumor-Specificity Growth Factor Combined with Tumor Markers in Nuclear Medicine Imaging to Identify Prostate Cancer Osteonosus ENSG00000226275 ENSG00000002330 ENSG00000110395 ENSG00000172936 ENSG00000175104 PMC3507315__F2 T cell receptor signaling pathway extracted from BioCarta database ENSG00000291603 ENSG00000213658 ENSG00000010810 ENSG00000177606 ENSG00000104368 PMC3507315__F3 Fc epsilon receptor I signaling in mast cell pathway extracted from BioCarta database ENSG00000010671 PMC3507315__F9 mTOR signaling pathway extracted from KEGG database ENSG00000157764 ENSG00000198793 ENSG00000164327 PMC7317062__F1 Neurofibromin is a negative RAS regulator ENSG00000186575 ENSG00000105397 ENSG00000198793 ENSG00000150457 ENSG00000146648 ENSG00000131023 ENSG00000196712 PMC2981516__F6 Demosponge EST Sequencing Reveals a Complex Genetic Toolkit of the Simplest Metazoans ENSG00000105656 PMC9469581__F5 TRIM proteins in hepatocellular carcinoma ENSG00000108395 ENSG00000213186 ENSG00000166326 ENSG00000291971 ENSG00000119401 ENSG00000141569 ENSG00000146054 ENSG00000198576 ENSG00000183718 ENSG00000166436 ENSG00000122779 ENSG00000291501 ENSG00000121060 ENSG00000140464 ENSG00000130726 PMC4924289__F1 Summary of the signalling pathways known to control the switch between dauer and growth in C ENSG00000189430 ENSG00000096264 PMC2948292__F1 Potential roles of BLM and RECQ5 in sister chromatid exchange regulation ENSG00000117525 ENSG00000197299 ENSG00000051180 PMC5008074__F3 MicroRNA (miRNA) biogenesis pathway and its regulation by Smad proteins ENSG00000128191 ENSG00000113360 ENSG00000132341 PMC6390811__F1 GPCR/Beta-arr-dependent signal pathways controlling cell survival, cytoskeleton remodeling, and gene expression, leading to enhanced cell growth, invasion and metastasis ENSG00000291971 ENSG00000006451 ENSG00000198793 ENSG00000168036 ENSG00000196628 PMC3834580__F2 Future of targeted agents in metastatic colorectal cancer ENSG00000198793 ENSG00000146648 PMC2013735__F4 GenMapp pathway showing the impact of 1 week of STZ-DM on transcription in pathways related to cytokines and the inflammatory response ENSG00000015285 ENSG00000164949 PMC6863766__F5 Metabolomics study of fasudil on cisplatin-induced kidney injury ENSG00000102977 ENSG00000026103 PMC4856801__F1 Proposed model depicting the opposing roles of type I and type II NKT cells in inflammatory diseases in the liver ENSG00000111537 ENSG00000112486 ENSG00000026103 PMC6470438__F6 Activating p38 MAPK intersection signaling pathway ENSG00000162889 ENSG00000070831 ENSG00000115415 ENSG00000114738 PMC4022190__F7 Biosynthetic pathway leading to the hypermodified tRNA base wybutosine (yW) ENSG00000198874 PMC9099196__F4 Gut homeostasis, injury, and healing: New therapeutic targets PMC7970828__F6 Synthesis Pathway and Protein-Protein Interaction (PPI) Network of the Elevated IGPs Modified by HM Glycans in Tumor ENSG00000041982 ENSG00000109861 ENSG00000083444 ENSG00000197746 ENSG00000277263 ENSG00000111885 ENSG00000137563 ENSG00000130175 PMC3056511__F7 Schematic summarizing the present findings ENSG00000163435 ENSG00000198793 PMC5362350__F1 Role of Autophagy in HIV Pathogenesis and Drug Abuse ENSG00000177169 ENSG00000152348 ENSG00000126775 ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC4424331__F11 The molecular mechanism of iron-induced RPE C3 production involves ERK1/2, SMAD3, and C/EBPD signaling ENSG00000221869 PMC4943391__F2 Melanocyte differentiation pathway dependent on MSHA and ACTH ENSG00000185231 ENSG00000107165 PMC3318211__F1 Signaling pathways involved in anthracycline-induced cardiomyocyte injury ENSG00000002330 ENSG00000285109 PMC8696122__F8 Brain and Pituitary Transcriptome Analyses Reveal the Differential Regulation of Reproduction-Related LncRNAs and mRNAs in Cynoglossus semilaevis ENSG00000109163 ENSG00000087245 ENSG00000113070 ENSG00000146648 PMC8890943__F13 Potential mechanism of MET alleviating COPD and CSE-induced GC resistance through activating Nrf2/HO-1 signaling pathway, which can promote the function and expression of MRP1 to increase the expression of HDAC2 ENSG00000288269 ENSG00000196591 ENSG00000145321 ENSG00000079999 PMC9109253__F1 Novel Small Molecule Approach for the Treatment of Propionic and Methylmalonic Acidemias. PMC4682803__F1 MTORC1 signaling to the translational machinery ENSG00000155506 ENSG00000155792 ENSG00000167965 PMC3962547__F14 Integration of metabolic control, cell growth and proliferation, and their regulation by phosphoinositides PMC5755497__F7A Expression Profiling of Differentiating Emerin-Null Myogenic Progenitor Identifies Molecular Pathways Implicated in Their Impaired Differentiation ENSG00000107404 ENSG00000171794 ENSG00000134982 ENSG00000101115 ENSG00000156925 ENSG00000156574 PMC5845450__F1 Central metabolic pathways of Geobacillus LC300 based on the genome annotation ENSG00000122966 ENSG00000166863 ENSG00000172005 PMC6940594__F4 ILK Signalling pathway generated using IPA ENSG00000196531 ENSG00000111057 ENSG00000138795 ENSG00000100985 ENSG00000089159 PMC3888279__F3 Regulation of hypoxia-inducible factor (HIF)–A expression or stabilization by pathways other than hypoxia ENSG00000100387 ENSG00000116030 ENSG00000146648 ENSG00000140443 PMC8824234__F2 Heterotopic Ossification: Clinical Features, Basic Researches, and Mechanical Stimulations ENSG00000170365 ENSG00000281324 ENSG00000162337 ENSG00000167941 ENSG00000020633 ENSG00000168036 ENSG00000096717 PMC11841850__F1 Heme biosynthetic pathway and multisystemic manifestations in EPP and XLP ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000158578 ENSG00000188690 PMC3237908__F4 Schematic diagram shows the possible effect of xanthones on the apoptosis pathways ENSG00000168040 PMC5462749__F8 Working model of Beta-Lap in acute pancreatitis ENSG00000162711 ENSG00000189403 ENSG00000096717 PMC11173086__F9 Proposed regulatory network of bulbil initiation in P ENSG00000134438 ENSG00000163788 PMC5037829__F2 UPR mechanism ENSG00000128272 ENSG00000127191 PMC5460122__F6 Lipotoxicity-induced NLRP3 inflammasome activation in TEC ENSG00000162711 ENSG00000135218 ENSG00000130164 ENSG00000125538 ENSG00000136869 ENSG00000096717 PMC3342643__F5 Diacylglycerol kinases in immune cell function and self-tolerance ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC8961591__F1 Pathophysiology of H2S in Renal Glomerular Diseases PMC5755497__F8A Expression Profiling of Differentiating Emerin-Null Myogenic Progenitor Identifies Molecular Pathways Implicated in Their Impaired Differentiation ENSG00000165197 ENSG00000112715 ENSG00000150630 PMC3744053__F5 Signaling pathways of anti-permeability factors ENSG00000291971 ENSG00000112715 PMC6953027__F2 Signaling and gene regulatory networks in pluripotent (naїve and primed) and teratocarcinoma stem cells ENSG00000165556 ENSG00000019991 ENSG00000137834 ENSG00000133937 ENSG00000138798 ENSG00000156574 ENSG00000187140 ENSG00000168036 ENSG00000127528 ENSG00000136826 ENSG00000071564 ENSG00000135446 ENSG00000241186 ENSG00000128342 ENSG00000119715 ENSG00000125968 PMC6953027__F1 TGFB Family Signaling Pathways in Pluripotent and Teratocarcinoma Stem Cells’ Fate Decisions: Balancing Between Self-Renewal, Differentiation, and Cancer ENSG00000019991 ENSG00000137834 ENSG00000105329 ENSG00000138798 ENSG00000156574 ENSG00000168036 ENSG00000130283 ENSG00000163217 ENSG00000164404 ENSG00000241186 ENSG00000177606 ENSG00000128342 ENSG00000175104 ENSG00000184344 PMC3070859__F1 Cohesin regulates expression of genes that control differentiation, morphogenesis, proliferation, and pluripotency ENSG00000101972 ENSG00000136997 ENSG00000164190 PMC6894227__F1 Metabolic pathway of DEGs related to lipid metabolism in the liver by DNA microarray analysis ENSG00000151726 ENSG00000116133 ENSG00000167910 ENSG00000036530 ENSG00000122787 ENSG00000113790 PMC4969764__F3 STRING v10.0 protein–protein interaction network based on input of 164 proteins of interest ENSG00000185608 ENSG00000047410 ENSG00000105290 ENSG00000142453 ENSG00000167371 ENSG00000113194 ENSG00000204316 ENSG00000145990 ENSG00000215114 ENSG00000166562 ENSG00000156299 ENSG00000058668 ENSG00000169813 ENSG00000100603 ENSG00000110711 ENSG00000276293 ENSG00000110107 ENSG00000060237 ENSG00000097096 ENSG00000278270 ENSG00000105323 ENSG00000099889 ENSG00000242247 ENSG00000011304 ENSG00000107282 ENSG00000188529 ENSG00000276429 PMC9369123__F4 PKC-MAPK Signalling Pathways in the Development of Hyperglycemia-Induced Cardiovascular Complications ENSG00000162692 PMC8490125__F3 Non-Coding RNAs: Master Regulators of Inflammasomes in Inflammatory Diseases ENSG00000278718 ENSG00000162711 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000265972 PMC11754893__F8 Mechanism diagram of MH regulating S100A8-CAMKK2-AMPK axis against cerebral IR injury ENSG00000143546 ENSG00000110931 PMC12182054__F1 FGF19-FGFR4-KLB signaling pathway ENSG00000160867 ENSG00000168036 PMC9454615__F5 Impact of COVID-19 on populations living at high altitude: Role of hypoxia-inducible factors (HIFs) signaling pathway in SARS-CoV-2 infection and replication ENSG00000104321 ENSG00000184012 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC2621116__F2 Representative plasmids used in this study PMC11953998__F5 Schematic illustrations showing different nano-targeting systems achieving precise mitochondrial localization and killing tumor cells through mtDNA perturbation (a–b) and metabolism disruption (c–d) ENSG00000183735 ENSG00000164430 PMC7564652__F3 AD pathway with target genes of upregulated miRNAs highlighted ENSG00000132906 ENSG00000142192 ENSG00000134982 ENSG00000115310 ENSG00000168040 ENSG00000281879 ENSG00000081051 ENSG00000127191 ENSG00000164305 ENSG00000102977 ENSG00000182511 ENSG00000120868 ENSG00000119912 PMC7564652__F4 AD pathway with target genes of downregulated miRNAs highlighted ENSG00000175054 ENSG00000142192 ENSG00000171105 ENSG00000002330 ENSG00000134982 ENSG00000198793 ENSG00000281879 ENSG00000168040 ENSG00000081051 ENSG00000119912 ENSG00000127191 PMC9454615__F2 Impact of COVID-19 on populations living at high altitude: Role of hypoxia-inducible factors (HIFs) signaling pathway in SARS-CoV-2 infection and replication ENSG00000104321 ENSG00000079999 PMC9454615__F3 Impact of COVID-19 on populations living at high altitude: Role of hypoxia-inducible factors (HIFs) signaling pathway in SARS-CoV-2 infection and replication ENSG00000130234 ENSG00000184012 PMC2868782__F3 Comparison of protein and gene expression studies ENSG00000198793 ENSG00000127948 PMC3668182__F2 Specification of GABAergic Cortical Interneurons ENSG00000106852 ENSG00000162624 ENSG00000006377 ENSG00000169840 ENSG00000164690 ENSG00000157005 ENSG00000004848 ENSG00000110693 PMC4521019__F2 Regulation of hepcidin expression by iron and inflammation ENSG00000170365 ENSG00000010704 ENSG00000106327 ENSG00000168610 PMC3833184__F3 Lineage-specific positive selection in the naked mole rat BRCA1/FANC pathway ENSG00000012048 ENSG00000144554 ENSG00000187741 ENSG00000051180 ENSG00000112039 ENSG00000158169 ENSG00000139618 PMC4931664__F1 Canonical NFKB pathway (left) induced by signals including antigens, TLR ligands and cytokines such as TNF uses a wide variety of signaling adaptors to engage and activate the IKKB subunit of the IKK complex ENSG00000104856 ENSG00000186716 PMC6331247__F2 Pathway for the relationship between MS4A6A SNPs, blood gene expression and Alzheimer’s disease phenotype ENSG00000038002 ENSG00000110077 PMC7836472__F5 Network pharmacology perspective for deciphering potential mechanisms of action of Solanum nigrum L. in bladder cancer ENSG00000198793 ENSG00000136997 ENSG00000146648 PMC8537037__F2 Abscopal Effect: A Review of Pre-Clinical and Clinical Advances ENSG00000164430 ENSG00000163599 ENSG00000189403 ENSG00000136869 PMC7664031__F7 Common altered signature as effect of multiple dose exposure to doxorubicine a Common altered up- and downregulated genes between P12 and P24 in Hs578T and MDA-MB-231 ENSG00000142621 ENSG00000157601 ENSG00000166592 PMC4732619__F7 FoxC2 Enhances BMP7-Mediated Anabolism in Nucleus Pulposus Cells of the Intervertebral Disc ENSG00000170365 ENSG00000176692 PMC3601410__F1 Nrf2 is bound to Keap1 in the cytoplasm ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC3601410__F2 Most of the studies on Nrf2 and obesity-metabolic syndrome have focused on liver and white adipose tissue ENSG00000148400 ENSG00000105550 ENSG00000106546 ENSG00000026103 PMC7136349__F2 Targeting of the complement cascade in antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis ENSG00000039537 ENSG00000113600 PMC8516647__F4 Functions of the XAF-1 protein in promoting p53 mediated apoptosis ENSG00000132530 ENSG00000181788 ENSG00000064393 PMC9699629__F3 Immunomodulatory Role of Thioredoxin Interacting Protein in Cancer’s Impediments: Current Understanding and Therapeutic Implications ENSG00000198793 ENSG00000265972 ENSG00000108788 ENSG00000168610 ENSG00000171303 PMC8619339__F3 Nanostring-Based Identification of the Gene Expression Profile in Trigger Finger Samples ENSG00000134982 ENSG00000167941 ENSG00000173156 ENSG00000113558 ENSG00000015285 ENSG00000100211 ENSG00000127948 PMC9699629__F1 Immunomodulatory Role of Thioredoxin Interacting Protein in Cancer’s Impediments: Current Understanding and Therapeutic Implications ENSG00000095787 ENSG00000084110 ENSG00000265972 PMC3708286__F2 Signaling pathways that relate disturbed polycystin-mediated Ca2+signaling to cell proliferation ENSG00000291971 PMC7671657__F1 PI3K signaling pathway ENSG00000104812 ENSG00000150907 ENSG00000146648 PMC6482165__F1 Hypothalamic regulation of energy homeostasis in healthy (blue) and obesity (pink) ENSG00000150907 ENSG00000198576 ENSG00000115138 ENSG00000124089 ENSG00000136869 ENSG00000166603 ENSG00000168610 PMC6935452__F2 Canonical and noncanonical Notch signaling pathway ENSG00000135547 ENSG00000090402 ENSG00000183979 ENSG00000168036 PMC11315658__F5 Synergism between TMEM16A and EGFR in mediating the proliferation of tumors ENSG00000168610 ENSG00000146648 PMC2751999__F6 LPA effect and signal transduction pathway ENSG00000159224 ENSG00000115415 ENSG00000198793 ENSG00000163914 ENSG00000136997 ENSG00000198670 PMC11083695__F1 Canonical hedgehog signaling pathway acts after the hedgehog (HH) ligands join the Patched-1 (PTCH-1) to release Smoothened (SMO) and enhance the translocation of glioma-associated oncogene (GLI) into the nucleus ENSG00000175879 ENSG00000103241 ENSG00000128602 PMC11083695__F2 Reappraisal of the Roles of the Sonic Hedgehog Signaling Pathway in Hepatocellular Carcinoma ENSG00000198793 ENSG00000163914 ENSG00000168036 ENSG00000128602 PMC4007467__F11 Proposed integrin signaling switch model ENSG00000291971 ENSG00000010810 PMC9137930__F4 Flavonoids-Based Delivery Systems towards Cancer Therapies ENSG00000120868 PMC7058935__F11 Wnt5b integrates with Fak1a to mediate cell movements during gastrulation ENSG00000070831 ENSG00000100592 ENSG00000291971 ENSG00000111186 PMC8500950__F1 Smoking‐aggravated oral candidiasis: Nrf2 pathway dampens NLRP3 inflammasome ENSG00000162711 ENSG00000181019 ENSG00000125538 PMC10627266__F5 CEBPB increases inflammation/SASP independent of DDR pathway to promote senescence ENSG00000149311 ENSG00000175054 ENSG00000081041 ENSG00000172216 ENSG00000168811 PMC2836783__F2 CD62L regulation by T-cell receptor (TCR) stimulation and Gc-cytokines ENSG00000291603 ENSG00000010810 ENSG00000150907 ENSG00000198793 ENSG00000164136 ENSG00000127528 ENSG00000126353 ENSG00000168685 PMC3364461__F4 PI3K/mTOR signaling at the FSHR ENSG00000198793 PMC6611790__F5 Hypothesis of the mechanism of IDH mutant gliomas ENSG00000173599 ENSG00000129151 PMC9399632__F3 Cancer and apoptosis: The apoptotic activity of plant and marine natural products and their potential as targeted cancer therapeutics ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC3364461__F1 Multiple transduction mechanisms induced at the FSHR ENSG00000157500 ENSG00000135446 ENSG00000146648 PMC3594038__F1 Btk activates antiapoptotic pathways ENSG00000002330 ENSG00000010671 PMC5276719__F2 Interconnections Between Autophagy and Integrin-Mediated Cell Adhesion ENSG00000110497 ENSG00000291971 ENSG00000146648 ENSG00000104081 PMC12150590__F5 Timeline of clinical trials of drugs targeting Wnt/Beta-catenin signaling pathway ENSG00000162337 ENSG00000102312 PMC12150590__F3 Wnt/Beta-catenin signaling pathway in cancer development and drug resistance ENSG00000167258 ENSG00000165556 ENSG00000169908 ENSG00000281324 ENSG00000162337 ENSG00000008952 ENSG00000134982 ENSG00000197405 ENSG00000176014 ENSG00000168036 ENSG00000108654 ENSG00000148429 ENSG00000099381 ENSG00000133216 ENSG00000131669 ENSG00000159216 ENSG00000117472 ENSG00000149809 ENSG00000004487 ENSG00000167468 ENSG00000177469 ENSG00000102312 ENSG00000105810 ENSG00000133135 PMC3403928__F4 Caspase cascade ENSG00000157131 PMC12150590__F4 Therapeutic strategies of targeted drugs in Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000102312 ENSG00000168036 PMC12150590__F1 Mechanism of canonical Wnt pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC12150590__F2 Mechanism of non-canonical Wnt signaling pathways ENSG00000087095 ENSG00000070831 ENSG00000134982 ENSG00000177606 ENSG00000168036 PMC6893874__F1 Diphthamide biosynthetic pathway ENSG00000148399 ENSG00000134146 PMC8663935__F4 Autophagy-targeted therapy to modulate age-related diseases: Success, pitfalls, and new directions ENSG00000177169 ENSG00000112561 PMC8573099__F6 Branched-Chain Amino Acids Catabolism Pathway Regulation Plays a Critical Role in the Improvement of Leukopenia Induced by Cyclophosphamide in 4T1 Tumor-Bearing Mice Treated With Lvjiaobuxue Granule ENSG00000110721 ENSG00000090402 ENSG00000100288 ENSG00000276559 ENSG00000087085 ENSG00000163751 ENSG00000038002 ENSG00000105205 ENSG00000070669 ENSG00000129219 ENSG00000100253 ENSG00000169291 ENSG00000291507 ENSG00000105135 ENSG00000105198 ENSG00000234032 ENSG00000173599 ENSG00000165078 ENSG00000172482 ENSG00000140284 ENSG00000113790 ENSG00000105552 ENSG00000121053 ENSG00000091140 ENSG00000116120 ENSG00000149313 ENSG00000089597 ENSG00000167701 ENSG00000114999 ENSG00000167419 ENSG00000151376 ENSG00000262785 ENSG00000141401 ENSG00000160883 ENSG00000138029 ENSG00000145982 ENSG00000257335 ENSG00000168137 ENSG00000166816 ENSG00000214013 ENSG00000115850 ENSG00000171759 ENSG00000005381 ENSG00000166123 ENSG00000159399 ENSG00000116761 ENSG00000084774 PMC8573099__F7 Branched-Chain Amino Acids Catabolism Pathway Regulation Plays a Critical Role in the Improvement of Leukopenia Induced by Cyclophosphamide in 4T1 Tumor-Bearing Mice Treated With Lvjiaobuxue Granule ENSG00000141401 ENSG00000171759 ENSG00000243056 ENSG00000139131 ENSG00000105552 ENSG00000091140 ENSG00000116761 PMC8423577__F3 Remodeling of Macrophages in White Adipose Tissue under the Conditions of Obesity as well as Lipolysis ENSG00000184344 ENSG00000168610 PMC9020200__F3 Cardiovascular informatics: building a bridge to data harmony ENSG00000178307 ENSG00000185591 ENSG00000100347 ENSG00000109756 PMC6533522__F2 SUMOylation‐mediated signalling pathway of cardiac hypertrophy ENSG00000116030 ENSG00000188612 ENSG00000184900 PMC12016104__F1 Metabolic pathway of the engineered G ENSG00000197713 PMC8663935__F1 Autophagy-targeted therapy to modulate age-related diseases: Success, pitfalls, and new directions ENSG00000177169 ENSG00000155792 ENSG00000112561 ENSG00000167965 PMC8663935__F2 Autophagy-targeted therapy to modulate age-related diseases: Success, pitfalls, and new directions ENSG00000177169 ENSG00000110497 ENSG00000152348 ENSG00000123395 ENSG00000198382 ENSG00000144848 ENSG00000070540 ENSG00000145782 ENSG00000057663 PMC8266377__F2 Homozygous Co-Deletion of Type I Interferons and CDKN2A Genes in Thoracic Cancers: Potential Consequences for Therapy ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000276561 ENSG00000142166 PMC11973335__F1 MPC mesengenic and angiogenic differentiation pathways are mutually exclusive ENSG00000178860 ENSG00000128917 ENSG00000166278 PMC6996551__F1 Cyclin D1–CDK4/6–RB and PI3K/AKT/mTOR pathways in BC ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000146648 PMC6384427__F2 NFKB and IRF3 signaling pathway regulation by miRNAs implicated in inflammatory diseases ENSG00000102871 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC5979333__F2 The NF2/merlin signaling pathway ENSG00000145041 ENSG00000126016 ENSG00000198793 ENSG00000136997 ENSG00000026508 ENSG00000168036 ENSG00000150457 ENSG00000187772 ENSG00000132849 ENSG00000131023 ENSG00000072415 PMC8856834__F3 Roles of circRNAs in Intervertebral Disc Degeneration: Inflammation, Extracellular Matrix Metabolism, and Apoptosis ENSG00000166167 ENSG00000125398 ENSG00000103888 PMC7997185__F1 NEK1 and NEK2 play key roles in the DDR pathway ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000134086 ENSG00000117650 ENSG00000181163 ENSG00000137601 ENSG00000187741 ENSG00000138385 ENSG00000198586 PMC5743230__F2 HYPOXIA AND PLACENTAL DEVELOPMENT ENSG00000173163 ENSG00000134086 ENSG00000166135 PMC7997185__F3 Possible involvement of NEK6 and NEK7 in DDR ENSG00000149311 ENSG00000175054 ENSG00000119408 PMC7997185__F5 Signaling pathway of NEK10 and NEK11 upon DNA damage ENSG00000114670 ENSG00000149311 ENSG00000175054 PMC3934873__F1 Iron Transport Machinery of Human Cells: Players and Their Interactions ENSG00000177575 ENSG00000115107 PMC2169177__F10 Schematic view of Ras- and calcineurin-dependent pathways in T cells ENSG00000291603 ENSG00000167941 ENSG00000141968 PMC4369815__F6 Schematic diagram of the signalling pathways involved in DEHP-induced Beta-cell dysfunction ENSG00000128272 ENSG00000144895 PMC3535184__F4 Ingenuity pathway analysis reveals the close relationship between 14 of 17 of most relevant genes in rectal cancer ENSG00000087245 ENSG00000112877 ENSG00000185885 ENSG00000081189 ENSG00000245848 ENSG00000116194 ENSG00000008516 ENSG00000101255 ENSG00000175832 ENSG00000156427 ENSG00000172594 ENSG00000198125 ENSG00000120729 ENSG00000130513 PMC7122270__F2 Type I/II cells ENSG00000168040 PMC2593676__F6 Gene expression and metabolite levels in the distal network pathways related to Met- and Trp-derived GS biosynthesis ENSG00000110395 PMC5755497__F11 Ingenuity pathway analysis of differentially expressed genes unique to emerin-null cells during transition from day 1 to day 2 of differentiation ENSG00000124102 ENSG00000135547 ENSG00000172380 ENSG00000070831 ENSG00000134982 ENSG00000291971 ENSG00000138798 ENSG00000103241 ENSG00000081189 ENSG00000166135 ENSG00000089159 ENSG00000038382 ENSG00000182533 ENSG00000092054 ENSG00000165887 ENSG00000136383 ENSG00000155657 PMC5755497__F12 Ingenuity pathway analysis of genes differentially expressed during the transition from differentiation day 0 to day 1 common to emerin-null cells and wildtype cells ENSG00000145824 ENSG00000091879 ENSG00000164305 ENSG00000166135 ENSG00000149311 ENSG00000175054 ENSG00000245848 ENSG00000168283 ENSG00000169245 ENSG00000182533 ENSG00000101945 ENSG00000118503 ENSG00000144857 ENSG00000150907 ENSG00000123374 ENSG00000165887 ENSG00000115593 ENSG00000076770 ENSG00000138100 ENSG00000283060 ENSG00000111913 ENSG00000139687 ENSG00000169375 ENSG00000278693 PMC7931689__F2 Identification of a functional network and laryngeal cancer-associated DEGs from the red-green overlapping DEGs ENSG00000186340 ENSG00000133110 ENSG00000038427 ENSG00000113140 ENSG00000087303 PMC9645326__F2 Potential Protective Role of GS-441524, a Metabolite of the Prodrug Remdesivir, in Vaccine Breakthrough SARS-CoV-2 Infections ENSG00000064601 ENSG00000130234 ENSG00000163631 PMC8687399__F10 Petri Net modelling approach for analysing the behaviour of Wnt/ ‐catenin and Wnt/ Ca2+ signalling pathways in arrhythmogenic right ventricular cardiomyopathy ENSG00000291983 ENSG00000148798 ENSG00000127191 ENSG00000164305 PMC7944918__F8 Gene ontology enrichment analysis of co-upregulated DEGs in both systemic sclerosis and lung cancer ENSG00000239732 ENSG00000170458 ENSG00000136869 ENSG00000131323 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000143387 PMC8083443__F1 Immunohistochemical analysis of Nuclear Factor-kappa B (NFKB) between follicular and plexiform ameloblastomas: A pilot study ENSG00000095585 ENSG00000226275 ENSG00000213658 ENSG00000170458 ENSG00000102871 ENSG00000186716 ENSG00000136997 ENSG00000111321 ENSG00000131323 ENSG00000083799 ENSG00000150455 ENSG00000127948 PMC3035636__F1 Targeting Metabolic Remodeling in Glioblastoma Multiforme ENSG00000136997 ENSG00000159399 PMC12124647__F7 Relationship between Oxidative Stress and Angiogenesis in RA ENSG00000164430 ENSG00000105953 ENSG00000005381 ENSG00000158125 PMC12124647__F8 Angiogenesis in rheumatoid Arthritis: Pathological characterization, pathogenic mechanisms, and nano-targeted therapeutic strategies ENSG00000291971 ENSG00000198793 ENSG00000112715 PMC3245201__F1 Topography and signaling pathways triggered by selectin ligands in neutrophils ENSG00000026508 ENSG00000197943 ENSG00000010671 PMC12124647__F6 Impact of Glycolysis in RA Angiogenesis ENSG00000180210 PMC12124647__F4 Abnormalities in EPC Phenotype and Vascular Barriers in RA Synovium ENSG00000162692 PMC6581914__F10 Scheme and working model ENSG00000121351 ENSG00000173599 PMC6966445__F1 Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling pathways (simplified) ENSG00000159128 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000027697 ENSG00000099942 ENSG00000102104 ENSG00000168610 ENSG00000276561 ENSG00000142166 PMC3037729__F1 Interaction between PI3K/Akt and Wnt signaling pathways mediates diverse cellular effects through downstream messengers ENSG00000150907 ENSG00000198793 ENSG00000168036 PMC6830099__F6 Putative model for the role of WIP1 in HR and in PARP inhibitor sensitivity ENSG00000143799 ENSG00000012048 ENSG00000291803 PMC3944966__F1 p-Hydroxyphenylpyruvate, an Intermediate of the Phe/Tyr Catabolism, Improves Mitochondrial Oxidative Metabolism under Stressing Conditions and Prolongs Survival in Rats Subjected to Profound Hemorrhagic Shock ENSG00000074800 ENSG00000171759 PMC4243732__F1 Cyclooxygenase and 5-lipoxygenase pathways with special reference to aspirin exacerbated respiratory disease ENSG00000226275 PMC2631376__F3 Hypothalamic Malonyl-Coenzyme A and the Control of Energy Balance ENSG00000115138 ENSG00000026103 PMC2919048__F7 Comparative Analysis of Extra-Embryonic Endoderm Cell Lines ENSG00000049323 ENSG00000170365 ENSG00000111537 ENSG00000100387 ENSG00000198742 ENSG00000166402 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000185591 ENSG00000164093 ENSG00000137801 PMC2919048__F8 Comparative Analysis of Extra-Embryonic Endoderm Cell Lines ENSG00000087095 ENSG00000172680 ENSG00000170458 ENSG00000149269 ENSG00000177606 ENSG00000130159 ENSG00000127191 ENSG00000196844 ENSG00000146648 ENSG00000026103 PMC8199681__F1 Molecular Details of the Frataxin–Scaffold Interaction during Mitochondrial Fe–S Cluster Assembly ENSG00000136003 PMC2277413__F4 Gene Network A ENSG00000065717 ENSG00000101057 ENSG00000139613 ENSG00000087586 ENSG00000124205 ENSG00000130726 ENSG00000164105 ENSG00000168118 PMC7346436__F8 Pathway signalling network of the common gene regulators associated with the top-ranking 100 CpG sites ENSG00000008710 ENSG00000047410 ENSG00000002330 ENSG00000175866 ENSG00000145147 ENSG00000178999 ENSG00000080345 ENSG00000168036 ENSG00000196220 ENSG00000197442 ENSG00000049618 ENSG00000049768 ENSG00000158445 ENSG00000010671 ENSG00000108840 ENSG00000076864 ENSG00000112290 ENSG00000084676 ENSG00000168214 ENSG00000154133 ENSG00000184384 ENSG00000143393 ENSG00000183943 ENSG00000152217 ENSG00000084112 ENSG00000291761 ENSG00000196498 ENSG00000124181 ENSG00000141378 ENSG00000166167 ENSG00000064309 ENSG00000104880 ENSG00000152495 ENSG00000085185 ENSG00000110048 ENSG00000173039 ENSG00000067900 ENSG00000105639 ENSG00000167641 ENSG00000086015 ENSG00000081189 ENSG00000149311 ENSG00000124216 ENSG00000100592 ENSG00000150867 ENSG00000146648 ENSG00000145349 ENSG00000178568 PMC2277413__F5 Gene Network B ENSG00000172534 ENSG00000135903 ENSG00000143162 ENSG00000185591 ENSG00000274803 ENSG00000139687 ENSG00000125968 ENSG00000155090 PMC4038991__F4 Circadian Redox and Metabolic Oscillations in Mammalian Systems ENSG00000123360 ENSG00000105835 ENSG00000132326 ENSG00000179094 PMC7093020__F2 Overview of crosstalk pathways associated with renal fibrosis and inflammation ENSG00000170365 ENSG00000150782 ENSG00000163235 ENSG00000138798 ENSG00000146648 PMC4669103__F4 Role of Innate and Adaptive Immunity in Cardiac Injury and Repair ENSG00000010810 ENSG00000172936 ENSG00000136869 PMC3228878__F1 Several types of TG2-containing adhesive / signaling complexes present on the cell surface ENSG00000281324 ENSG00000162337 ENSG00000291971 ENSG00000168036 PMC6944044__F2 Linc00152 is involved in protein activation ENSG00000012048 ENSG00000146648 PMC7492540__F1 Schematic of known pathways regulated by AR in various breast cancer subtypes ENSG00000188064 ENSG00000136997 ENSG00000124766 ENSG00000168036 ENSG00000129514 PMC9250250__F5 Proteomics-based investigation of cerebrovascular molecular mechanisms in cerebral amyloid angiopathy by the FFPE-LMD-PCT-SWATH method ENSG00000172380 ENSG00000108861 ENSG00000175220 ENSG00000221914 ENSG00000124491 ENSG00000176014 ENSG00000104833 ENSG00000131095 ENSG00000120885 ENSG00000100243 ENSG00000166147 ENSG00000135624 ENSG00000013583 ENSG00000197956 ENSG00000004478 ENSG00000066044 ENSG00000165478 ENSG00000161533 ENSG00000171914 ENSG00000026508 ENSG00000110435 ENSG00000111540 ENSG00000140464 PMC8852695__F8 Short‐term tetrabromobisphenol A exposure promotes fibrosis of human uterine fibroid cells in a 3D culture system through TGF‐beta signaling ENSG00000133937 ENSG00000156574 ENSG00000276561 PMC8454773__F1 Interkingdom Comparison of Threonine Metabolism for Stem Cell Maintenance in Plants and Animals ENSG00000136877 ENSG00000175567 PMC7431475__F11 Additional examples on TA-based MECs ENSG00000196549 ENSG00000128602 PMC11703843__F1 LLPS and signalling pathways in the cytoplasm of healthy liver cells and HCC cells ENSG00000134070 ENSG00000139926 ENSG00000157625 ENSG00000175104 ENSG00000184216 PMC8756734__F1 Biological Clock Pathways Are Complex and May Yield Variable Outcomes ENSG00000198793 ENSG00000096717 PMC10036500__AF1 MACF1 overexpression in BMSCs alleviates senile osteoporosis in mice through TCF4/miR-335–5p signaling pathway ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC3291787__F1B Targeting the EGFR signaling pathway in cancer therapy ENSG00000113905 ENSG00000163235 ENSG00000113070 ENSG00000138798 PMC6682713__F1 LncRNAs regulate angiogenesis through modulating multiple signaling pathways ENSG00000164252 ENSG00000167772 ENSG00000198793 ENSG00000112715 ENSG00000168610 PMC6707130__F1 Developmental Alcohol and Circadian Clock Function ENSG00000146469 PMC10675562__F6 HS potential inhibitory mechanism of GA via TGFB/Smad signaling pathway PMC2724779__F1 Complexity of sphingolipid biosynthetic pathways ENSG00000139624 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000143418 PMC7189493__F7 Effect of X-rays on transcript expression of rat brain microvascular endothelial cells: role of calcium signaling in X-ray-induced endothelium damage ENSG00000182533 ENSG00000156026 ENSG00000186716 PMC7930566__F2 Schematic portrayal of the possible mechanisms of mifepristone as a chemo-sensitizing agent for glioblastoma ENSG00000170430 ENSG00000171791 PMC4421107__F1 Energetic and biosynthetic functions of de novo lipogenesis (DNL) in the control of metabolic homeostasis ENSG00000131473 ENSG00000079432 ENSG00000026103 PMC8600187__F4 Potential Application of Chinese Medicine in Liver Diseases: A New Opportunity ENSG00000181019 ENSG00000172005 ENSG00000113520 ENSG00000172936 ENSG00000136869 PMC8259581__F1 Corrigendum: Signaling Pathways Regulating Thermogenesis ENSG00000135482 ENSG00000106459 PMC9322645__F8 Molecular Processes of Dodder Haustorium Formation on Host Plant under Low Red/Far Red (R/FR) Irradiation ENSG00000189060 ENSG00000105227 ENSG00000084774 PMC8259581__F2 Corrigendum: Signaling Pathways Regulating Thermogenesis ENSG00000170365 PMC7295575__F5 Summary of the proposed pathway ENSG00000253506 ENSG00000148400 ENSG00000137845 ENSG00000103335 PMC8817700__F1 Targeting Toll-Like Receptors in Sepsis: From Bench to Clinical Trials ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC3432650__F1 How does Lin28 let-7 control development and disease? ENSG00000131914 ENSG00000187772 ENSG00000128191 ENSG00000113360 PMC3770684__F3 SNP (–617C>A) in ARE-Like Loci of the NRF2 Gene: A New Biomarker for Prognosis of Lung Adenocarcinoma in Japanese Non-Smoking Women ENSG00000178573 ENSG00000118777 ENSG00000079999 PMC4576673__F5 Summary of endogenous pathways of AHR ligand synthesis ENSG00000112715 ENSG00000073756 ENSG00000106546 PMC5578145__F8 Changes in the photosynthetic electron transfer chain, Calvin cycle, and biosynthesis pathway of sucrose and starch in response to rapid changes in temperature in M ENSG00000182511 ENSG00000173599 PMC4600508__F2 Schematic overview of the multiple signaling pathways to apoptosis, necroptosis and autophagy ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC6288939__F4 Expression differences in males and females in response to reduced insulin signaling for immune response genes ENSG00000112977 ENSG00000171759 ENSG00000168040 ENSG00000177084 PMC7677403__F2 Toll-like receptors (TLRs) mediated signal transduction pathway ENSG00000239732 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC9685408__F2 Mechanical forces in lymphatic vessel development: Focus on transcriptional regulation ENSG00000157557 ENSG00000176692 ENSG00000164736 ENSG00000117707 ENSG00000203883 ENSG00000111642 PMC7677403__F3 cGAS/STING- mediated signal transduction pathway ENSG00000183735 ENSG00000164430 ENSG00000276561 PMC6288939__F6 Expression differences within the IIS/TOR pathway for the four comparison types ENSG00000198793 ENSG00000136997 PMC12061282__F10 Schematic depicting the mechanisms by which miR‐31‐5p regulates M1/M2 balance in autoimmune dry eye ENSG00000089041 ENSG00000007171 PMC5770784__F1 Schematic drawing of the interactions between AB(1‐42) and IGF‐I receptor signaling ENSG00000140443 PMC7677403__F1 RIG-I-like receptors (RLRs) mediated signal transduction pathway ENSG00000088888 ENSG00000276561 PMC7795494__F2 Comparison between the opposite effects of probiotics and early-life use of antibiotics in NOD mice ENSG00000096395 ENSG00000172936 ENSG00000136869 PMC8070500__F2 JNK pathway in CNS pathologies ENSG00000119138 ENSG00000162772 PMC8070500__F1 JNK pathway is conserved between mammals and flies ENSG00000177606 ENSG00000132478 PMC3161872__F1 Summary of TNFR signalling ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC4470683__F7 Deciphering Signaling Pathway Networks to Understand the Molecular Mechanisms of Metformin Action ENSG00000136997 ENSG00000185591 ENSG00000124762 PMC4988307__F1 Sulforaphane regulates Keap1-Nrf2-ARE signaling pathway and induces phase II metabolic enzyme expression ENSG00000175793 ENSG00000079999 PMC9524954__F7 Alpha-KG production pathways that add net carbons to TCA cycle from glutamine ENSG00000125166 ENSG00000166123 PMC6571700__F8 Signaling pathways modulated by EV miRNAs associated with T2DM ENSG00000171105 ENSG00000148400 ENSG00000150907 ENSG00000073792 ENSG00000114166 PMC2516940__F2 Sepsis and insights from clinical trials ENSG00000172005 ENSG00000172936 ENSG00000136869 PMC5361607__F1 PRKCD-AKT-MTOR-ULK1 signaling pathway for autophagy suppression in cisplatin nephrotoxicity ENSG00000140992 ENSG00000177169 ENSG00000291971 ENSG00000198793 PMC3390502__F8 Mechanical stress-activated immune response genes via Sirtuin 1 expression in human periodontal ligament cells ENSG00000125538 ENSG00000096717 ENSG00000115009 PMC7677403__F4 Inflammasome-mediated signal transduction pathway ENSG00000162711 ENSG00000163568 ENSG00000163565 ENSG00000276561 ENSG00000164342 PMC8163070__F6 Phloretin protection against pathogen-induced mucin 5AC, oligomeric mucus/gel-forming (MUC5AC) ENSG00000291363 ENSG00000086991 ENSG00000136869 ENSG00000146648 PMC3761286__F1 Diagram showing Na-K-ATPase control of cell function by ouabain via its ion transport and signaling functions ENSG00000291971 ENSG00000146648 PMC8120650__F3 Autophagy-related signaling pathways are involved in cancer (Review) ENSG00000198793 ENSG00000136997 ENSG00000118515 ENSG00000155792 ENSG00000102007 ENSG00000164327 ENSG00000167965 ENSG00000188322 PMC8120650__F4 Autophagy-related signaling pathways are involved in cancer (Review) ENSG00000177169 ENSG00000198793 PMC8120650__F5 Autophagy-related signaling pathways are involved in cancer (Review) ENSG00000128272 ENSG00000070831 ENSG00000144895 ENSG00000138798 ENSG00000005893 ENSG00000171791 ENSG00000057663 ENSG00000079999 PMC6923169__F2 Biosynthesis of N-glycoproteins in eukaryotic cells ENSG00000101901 ENSG00000146416 ENSG00000069482 ENSG00000139133 ENSG00000033011 ENSG00000088035 ENSG00000214160 PMC6817752__F11 Schematic showing the proposed mechanism of action and regulation of HNRNPK/miR-7 ENSG00000171105 ENSG00000165119 ENSG00000185591 ENSG00000160179 ENSG00000119912 ENSG00000136826 PMC7463546__F1 NFKB signaling pathway and anti-multiple myeloma (MM) drug targets ENSG00000104856 ENSG00000138798 ENSG00000082512 ENSG00000173039 ENSG00000111321 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000146648 PMC8109088__F8 Proposed model illustrated the role of hsa_circ_0110102/miR-580-5p/PPARA/CCL2 signaling in regulating HCC metastasis ENSG00000108691 ENSG00000121807 PMC3086058__F1 Representation of genes of the vascular endothelial growth factor (VEGF) signaling pathway and the sites at which bevacizumab, sorafenib, sunitinib, brivanib, and cilengitide are known to act ENSG00000100234 ENSG00000128052 ENSG00000115904 ENSG00000112715 PMC9599894__F5 Radiotherapy-Related Gene Signature in Prostate Cancer ENSG00000072694 ENSG00000169550 ENSG00000198851 ENSG00000159461 ENSG00000274736 ENSG00000126353 ENSG00000273936 ENSG00000177106 PMC11209433__F5 Interactions among genes involved in the type 1 interferon signaling pathway using STRING (Search Tool for the Retrieval of Interacting Genes/Proteins) ENSG00000169248 ENSG00000116663 ENSG00000187608 ENSG00000163519 ENSG00000163739 ENSG00000157601 ENSG00000095015 ENSG00000163751 ENSG00000121236 ENSG00000049768 ENSG00000136695 ENSG00000144476 ENSG00000239732 ENSG00000134321 ENSG00000196549 ENSG00000163734 ENSG00000173578 ENSG00000277263 ENSG00000136697 ENSG00000145824 ENSG00000138795 ENSG00000081041 ENSG00000109320 ENSG00000204671 ENSG00000136694 ENSG00000108342 ENSG00000185745 ENSG00000140287 ENSG00000007908 ENSG00000285152 ENSG00000257335 ENSG00000116157 ENSG00000073756 ENSG00000169245 ENSG00000186810 ENSG00000112116 ENSG00000108691 ENSG00000110395 ENSG00000135114 ENSG00000131323 ENSG00000111331 PMC8450384__F4 Glucose Metabolism and Glucose Transporters in Breast Cancer ENSG00000092621 ENSG00000159399 PMC5899410__F3 TREM2 mediated innate immune regulation in Alzheimer’s disease ENSG00000125538 ENSG00000168036 PMC4232216__F1 BMP Family and Signaling Pathways ENSG00000170365 ENSG00000137834 ENSG00000130385 ENSG00000152785 ENSG00000135414 ENSG00000168487 ENSG00000163217 PMC5468173__F4 An illustration of potential mechanisms in injury-induced vascular intimal hyperplasia is depicted ENSG00000172936 ENSG00000136869 PMC9163386__F6 Component 1 Inhibitor Missense (Val480Met) Variant Is Associated With Gene Expression and Sepsis Development in Neonatal Lung Disease ENSG00000277571 ENSG00000009724 ENSG00000244731 ENSG00000088926 ENSG00000164344 ENSG00000122194 ENSG00000182326 ENSG00000104368 ENSG00000236625 PMC7354650__F4 Network Pharmacology Approach to Investigate the Active Compounds and Mechanisms of Musk for Ischemic Stroke ENSG00000162552 ENSG00000150594 ENSG00000184845 ENSG00000196591 ENSG00000125686 ENSG00000082556 ENSG00000127948 PMC3557799__F3 Structures of Get3, Get4, and Get5 Provide New Models for TA Membrane Protein Targeting ENSG00000198356 ENSG00000182093 ENSG00000239857 PMC9602906__F8 Exosomes Derived from Adipose-Derived Mesenchymal Stem Cells on Pyroptosis and Regeneration of Injured Liver ENSG00000278718 ENSG00000162711 ENSG00000168036 ENSG00000136869 PMC4641524__F4 Differential Somatostatin Receptor (SSTR) 1-5 Expression and Downstream Effectors in Histologic Subtypes of Growth Hormone Pituitary Tumors3.1 ENSG00000110711 ENSG00000291971 ENSG00000180616 PMC3357464__F3 Scaffolds can organize pleiotropic kinases into stimulus-specific signaling modules to direct them to one specific pathway ENSG00000065559 ENSG00000157625 ENSG00000127191 PMC5114727__F1 Enzymatic steps of the P ENSG00000138621 ENSG00000127125 PMC11119900__F3 PAI-1 alters TME and regulates tumor cell migration and invasion ENSG00000122194 PMC9506158__F3 ORF45 Protein of Kaposi’s Sarcoma-Associated Herpesvirus and Its Critical Role in the Viral Life Cycle ENSG00000183735 ENSG00000276561 PMC10041561__F17 Bakuchiol and Ethyl (Linoleate/Oleate) Synergistically Modulate Endocannabinoid Tone in Keratinocytes and Repress Inflammatory Pathway mRNAs ENSG00000089127 ENSG00000117480 ENSG00000183486 ENSG00000157601 ENSG00000196689 ENSG00000164342 PMC11206879__F3 Alterations in major signaling pathways that have been identified in OS development and metastasis: PI3K/AKT/mTOR, JAK/STAT, Wnt/Beta-catenin, NOTCH, Hedgehog/Gli, TGFB, MAPK, and receptor tyrosine kinases (RTKs) ENSG00000137834 ENSG00000281324 ENSG00000162337 ENSG00000198793 ENSG00000164690 ENSG00000114315 ENSG00000128602 ENSG00000128564 ENSG00000168610 PMC7365123__F1 Putative association between ACE2 shedding after SARS-CoV-2 infection and the poor outcomes in elderly COVID-19 patients with pre-existing age-related cardiovascular, cardiometabolic and cardiorenal diseases ENSG00000130234 ENSG00000198793 ENSG00000184012 PMC10041561__F15 Bakuchiol and Ethyl (Linoleate/Oleate) Synergistically Modulate Endocannabinoid Tone in Keratinocytes and Repress Inflammatory Pathway mRNAs ENSG00000115718 PMC6529740__F2 Potential and confirmed phenotypic features of C9orf72 HRE-associated microglia in FTLD/ALS ENSG00000173369 ENSG00000011600 ENSG00000129226 ENSG00000147894 ENSG00000132341 PMC8000072__F6 Proposed pathway by which SCFAs regulate lipid metabolism in a sex-specific manner in Long–Evans rats ENSG00000042832 ENSG00000167910 ENSG00000120437 PMC2652039__F8 Tumor Necrosis Factor-like Weak Inducer of Apoptosis (TWEAK) activates proinflammatory signaling pathways and gene expression through the activation of TGF-beta activated kinase 1 ENSG00000108691 ENSG00000082512 ENSG00000056558 ENSG00000131323 ENSG00000162692 ENSG00000127191 PMC5234130__F4 Terpene biosynthetic pathway, and heatmaps displaying the expression (log2 FPKM) of enzymes involved in the different reaction steps ENSG00000110921 ENSG00000197429 ENSG00000167508 ENSG00000082212 PMC8848383__F8 Activation of the AKT/GSK-3B/Beta-catenin pathway via photobiomodulation therapy promotes neural stem cell proliferation in neonatal rat models of hypoxic-ischemic brain damage ENSG00000077150 ENSG00000136997 ENSG00000168036 PMC9219473__F6 Iturin A Rescued STb-R-Induced Pork Skeletal Muscle Growth Restriction through the Hypothalamic-Pituitary-mTORC1 Growth Axis ENSG00000291972 ENSG00000169047 PMC4760220__F7 AAV backbone alone has no effect on interferon activation ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000033800 ENSG00000185745 ENSG00000125347 ENSG00000230034 PMC6438741__F3 At the intersection of DNA damage and immune responses ENSG00000095585 ENSG00000149311 ENSG00000002330 ENSG00000150907 ENSG00000137193 ENSG00000137265 ENSG00000175097 ENSG00000166211 ENSG00000168685 ENSG00000292210 PMC4891443__F5 Regulation of insulin-like growth factor 1 receptor signaling by microRNA-4458 ENSG00000149968 ENSG00000140443 PMC7711227__F2 CaMK, MAPK/ERK, and CaN Signaling From L-VSCCs to Transcription ENSG00000142178 ENSG00000105662 PMC9516679__F9 Alcohol promotes epithelial mesenchymal transformation-mediated premetastatic niche formation of colorectal cancer by activating interaction between lamininG2 and integrinB1 ENSG00000058085 ENSG00000170558 PMC6438741__F6 At the intersection of DNA damage and immune responses ENSG00000149311 ENSG00000160741 PMC7825147__F2 Tumor suppressor and promoting effects of the TGFB pathway ENSG00000149311 ENSG00000167772 ENSG00000276618 ENSG00000134982 ENSG00000283060 ENSG00000146648 ENSG00000125968 PMC6459935__F1 Bioinformatics analysis of direct ERRA target genes in mouse liver PMC8828488__F1 ROS-Induced NLRP3 Inflammasome Activation in the Formation of Calcium Oxalate Nephrolithiasis ENSG00000162711 ENSG00000125538 ENSG00000173786 ENSG00000026508 ENSG00000265972 PMC7825147__F1 Transforming growth factor B (TGFB) signaling pathway ENSG00000198793 ENSG00000132478 PMC6206158__F1 Complement activation pathway and regulation ENSG00000039537 ENSG00000009724 ENSG00000291559 ENSG00000203710 ENSG00000117335 ENSG00000244731 ENSG00000182326 ENSG00000236625 PMC8257394__F4 Network Pharmacology and Bioinformatics Methods Reveal the Mechanism of Zao-Jiao-Ci in the Treatment of LSCC ENSG00000139437 ENSG00000064601 ENSG00000099985 ENSG00000110799 ENSG00000165409 ENSG00000105402 ENSG00000132849 ENSG00000106346 ENSG00000092820 ENSG00000148848 ENSG00000174444 ENSG00000172530 PMC6540932__F6 Network view of infected dendritic cells ENSG00000104856 ENSG00000167207 ENSG00000187608 ENSG00000291971 ENSG00000198793 ENSG00000108342 ENSG00000106100 ENSG00000168811 ENSG00000277943 ENSG00000101695 ENSG00000150782 ENSG00000111537 ENSG00000150991 ENSG00000141480 ENSG00000136869 ENSG00000164342 PMC5135602__F1 PPARD mediated gene regulation ENSG00000111537 ENSG00000168036 ENSG00000184916 PMC3250080__F1 CR-associated signaling and some of its key players ENSG00000112964 ENSG00000169047 ENSG00000140443 PMC8820534__F1 High Cysteine Diet Reduces Insulin Resistance in SHR-CRP Rats ENSG00000137767 ENSG00000139531 ENSG00000116761 PMC4822853__F3 Functional Response of B Cells to Antigenic Stimulation: A Preliminary Report of Latent Tuberculosis ENSG00000111537 ENSG00000197272 ENSG00000113520 ENSG00000162892 PMC3023615__F2 In fibroblasts, Nod2 senses bacteria at the plasma membrane and recruits the autophagic machinery through direct interaction with ATG16L1 ENSG00000167207 ENSG00000120697 ENSG00000145782 PMC4309023__F6 Core Hedgehog pathway and its cross talks ENSG00000152266 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC5578810__F2A Fanconi Anemia Protein Interaction Network: Casting A Wide Net ENSG00000175054 ENSG00000164053 ENSG00000132646 PMC3690688__F8 Oestrogen promotes KCNQ1 potassium channel endocytosis and postendocytic trafficking in colonic epithelium ENSG00000001626 PMC9144222__F10 Crassolide Induces G2/M Cell Cycle Arrest, Apoptosis, and Autophagy in Human Lung Cancer Cells via ROS-Mediated ER Stress Pathways ENSG00000128272 ENSG00000144895 ENSG00000134057 ENSG00000164305 PMC6862548__F1 Pathways activated by several dysregulated hormones in central obesity ENSG00000002330 ENSG00000109320 ENSG00000010810 ENSG00000198793 ENSG00000115904 ENSG00000173039 ENSG00000159346 ENSG00000162924 ENSG00000285070 ENSG00000213341 ENSG00000168610 PMC6862548__F2 Estrogen biogenesis, and its metabolism ENSG00000291971 ENSG00000185591 PMC8622245__F1 An Overview of Recent Insights into the Response of TLR to SARS-CoV-2 Infection and the Potential of TLR Agonists as SARS-CoV-2 Vaccine Adjuvants ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC7919658__F3 Oxysterol and BA profiles by the hepatic endocannabinoid and immune system in male mice ENSG00000160867 ENSG00000167910 ENSG00000180432 ENSG00000172936 ENSG00000135929 PMC4668392__F1 Multiple regulation pathways and pivotal biological functions of STAT3 in cancer ENSG00000070831 ENSG00000291971 ENSG00000168610 PMC11215460__F1 Overexpression of Plakophilin2 Mitigates Capillary Leak Syndrome in Severe Acute Pancreatitis by Activating the p38/MAPK Signaling Pathway ENSG00000161798 ENSG00000168036 ENSG00000057294 PMC8948438__F2 Exploring the Pharmacological Mechanisms of Xihuang Pills Against Prostate Cancer via Integrating Network Pharmacology and Experimental Validation In Vitro and In Vivo ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000002330 ENSG00000179091 ENSG00000104894 ENSG00000291368 PMC2683291__F4 Mammalian target of rapamycin (mTOR) signalling cascade ENSG00000198793 PMC2757047__F3 Alternative functions of core cell cycle regulators in neuronal migration, neuronal maturation, and synaptic plasticity ENSG00000153993 ENSG00000122691 PMC5362541__F2 Inhibition of cancer antioxidant defense by natural compounds ENSG00000100387 ENSG00000079999 PMC4582071__F3 Intracellular pathways to canalicular and basolateral plasma membranes ENSG00000005471 ENSG00000073734 ENSG00000023839 PMC12064105__F7 Mechanism diagram of XSBO against AD (drawn by Figdraw 2 ENSG00000275565 ENSG00000102172 PMC8727999__F2 Concepts in Multifactorial Etiology of Developmental Disorders: Gene-Gene and Gene-Environment Interactions in Holoprosencephaly ENSG00000043355 ENSG00000064309 ENSG00000119977 ENSG00000177426 ENSG00000138002 ENSG00000180447 ENSG00000160973 ENSG00000138083 ENSG00000156574 ENSG00000011143 ENSG00000164690 ENSG00000077782 PMC8329661__F2 Can Nimesulide Nanoparticles Be a Therapeutic Strategy for the Inhibition of the KRAS/PTEN Signaling Pathway in Pancreatic Cancer? ENSG00000135446 ENSG00000120868 ENSG00000105810 PMC8329661__F3 Can Nimesulide Nanoparticles Be a Therapeutic Strategy for the Inhibition of the KRAS/PTEN Signaling Pathway in Pancreatic Cancer? ENSG00000159224 ENSG00000198793 ENSG00000146648 PMC5072448__F1 Molecular mechanisms and signaling pathways of ferroptosis ENSG00000168003 ENSG00000122025 ENSG00000167107 ENSG00000151012 ENSG00000078668 ENSG00000167468 ENSG00000167996 ENSG00000111684 ENSG00000136381 ENSG00000062485 PMC9303011__F2 Constraint-Based Reconstruction and Analyses of Metabolic Models: Open-Source Python Tools and Applications to Cancer PMC7044202__F9 MAPK regulated induction of cytokines in IL-33 stimulated ILC2s ENSG00000137033 ENSG00000198793 ENSG00000172936 PMC11019147__F4 Osteoclasts and osteoarthritis: Novel intervention targets and therapeutic potentials during aging ENSG00000124181 ENSG00000175104 ENSG00000131196 PMC8329661__F5 Can Nimesulide Nanoparticles Be a Therapeutic Strategy for the Inhibition of the KRAS/PTEN Signaling Pathway in Pancreatic Cancer? PMC7480187__F7 Alleviation prostate cancer progression via overexpresion of RIP3 ENSG00000134057 ENSG00000145386 ENSG00000168404 PMC10740485__F7 The proposed mechanism of Nrf2 in osteoporosis ENSG00000164935 ENSG00000175104 ENSG00000131196 PMC11019147__F3 Osteoclasts and osteoarthritis: Novel intervention targets and therapeutic potentials during aging ENSG00000177169 ENSG00000127528 ENSG00000171791 ENSG00000175104 PMC11019147__F1 Osteoclasts and osteoarthritis: Novel intervention targets and therapeutic potentials during aging ENSG00000293604 ENSG00000131323 ENSG00000124181 ENSG00000175104 ENSG00000131196 PMC5508477__F6 Representative scheme of the mechanisms involved in the induction of cell cycle arrest and senescence.MPM cell lines are frequently deleted in CDKN2A/ARF gene, coding for both p16INK4a and p14ARF ENSG00000135446 ENSG00000136997 ENSG00000105810 PMC9454318__F5 Alpiniae oxyphyllae fructus possesses neuroprotective effects on H2O2 stimulated PC12 cells via regulation of the PI3K/Akt signaling Pathway ENSG00000087085 ENSG00000171791 ENSG00000099194 ENSG00000121879 ENSG00000157212 ENSG00000164305 ENSG00000069667 ENSG00000104154 ENSG00000143801 ENSG00000109861 ENSG00000082175 ENSG00000128052 ENSG00000036530 ENSG00000123374 ENSG00000108821 ENSG00000283060 ENSG00000077782 ENSG00000146648 ENSG00000253729 ENSG00000125968 ENSG00000140443 ENSG00000172201 PMC8306267__F2 Coagulation and Complement Factors for Mast Cell Activation in the Pathogenesis of Chronic Spontaneous Urticaria ENSG00000180210 ENSG00000122194 PMC5143376__F8 Hypothetical model of TMEM2 exerting its antiviral functions ENSG00000213928 ENSG00000105397 ENSG00000089127 PMC4981961__F6 Phagocytosis and proteasome pathways ENSG00000213658 ENSG00000148798 ENSG00000188404 PMC6599063__F4 Simplified schematic representation of the affected pathways in an emerging honeybee worker that impact Varroa and DWV symptoms via their interactions ENSG00000198793 PMC5683946__F2 NMD degrades mRNAs encoding UPR components ENSG00000106701 ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000162772 ENSG00000127191 PMC4742123__F2 Adaptive responses of androgen receptor signaling in castration-resistant prostate cancer ENSG00000101871 ENSG00000291971 PMC10217556__F1 Urothelial Oxidative Stress and ERK Activation Mediate HMGB1-Induced Bladder Pain ENSG00000019582 ENSG00000189403 ENSG00000136869 ENSG00000121966 PMC3883113__F6 Neurodegenerative diseases and widespread aggregation are associated with supersaturated proteins ENSG00000132906 ENSG00000291983 ENSG00000142192 ENSG00000002330 ENSG00000104044 ENSG00000120868 ENSG00000168040 ENSG00000119912 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC5480880__F6 Bilateral blockade of MEK- and PI3K-mediated pathways downstream of mutant KRAS as a treatment approach for peritoneal mucinous malignancies ENSG00000157764 ENSG00000065361 ENSG00000148204 ENSG00000135333 PMC6431505__F6 Schematic graph of the proposed cardioprotective mechanism of H2 when rats were exposed to CIH ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC11046830__F2 Glycocalyx degradation in LPS or septic conditions ENSG00000003436 ENSG00000110799 ENSG00000134982 PMC11046830__F3 Oxidative stress response in ECs ENSG00000162711 ENSG00000182511 ENSG00000004142 ENSG00000086991 PMC5683946__F6 NMD and apoptosis have a complex regulatory relationship I ENSG00000118515 ENSG00000132478 ENSG00000116717 PMC8968663__F1 Revolution of vitamin E production by starting from microbial fermented farnesene to isophytol ENSG00000067064 ENSG00000173599 ENSG00000197429 PMC11046830__F4 Cascade of effects resulting from the release of IL-33 under the action of endothelial injury and other factors ENSG00000108702 ENSG00000087245 ENSG00000137033 ENSG00000100985 ENSG00000162692 ENSG00000005381 ENSG00000168610 PMC12192587__F4 Muscle Fiber Phenotype Shifts in Response to ECM Coatings ENSG00000117054 ENSG00000135218 ENSG00000106459 PMC4348787__F7 Fungus-induced changes in expression of the wheat jasmonate biosynthesis pathway ENSG00000090402 PMC8375153__F1 Mechanisms of Sevoflurane-Induced Neuroinflammation PMC11968360__F1 Organoid models of ovarian cancer from three different sources ENSG00000115221 ENSG00000159399 ENSG00000139618 ENSG00000164916 PMC12211009__F10 BACE1-AS in the regulation of the propagation of C ENSG00000171791 PMC4452147__F3 Schematic illustrations of a double-negative feedback loop and the ceRNA pathway PMC11506204__F3 Signal pathways of astragaloside IV in breast cancer ENSG00000134215 ENSG00000150907 PMC11506204__F1 Signal pathways of calycosin in breast cancer ENSG00000041353 ENSG00000156127 ENSG00000108551 ENSG00000049768 PMC11506204__F2 Signal pathways of formononetin in breast cancer ENSG00000135446 ENSG00000198793 ENSG00000171049 PMC2722780__F8 Putative BK-BKAP interactions derived from the BK interactome in mouse cochlea ENSG00000002330 ENSG00000148943 PMC4048824__F2 Pathways for sulfide biogenesis and clearance PMC3792444__F1 Induction of migratory heterogeneity during priming ENSG00000186810 ENSG00000111537 ENSG00000150907 ENSG00000145321 ENSG00000026508 ENSG00000127528 ENSG00000126353 ENSG00000092820 PMC8346999__F8 Signaling Pathways Regulated by UBR Box-Containing E3 Ligases ENSG00000012048 ENSG00000106683 ENSG00000111859 ENSG00000137275 ENSG00000056558 ENSG00000159459 ENSG00000102010 PMC8346999__F9 Signaling Pathways Regulated by UBR Box-Containing E3 Ligases ENSG00000175193 ENSG00000127481 ENSG00000158828 ENSG00000159459 PMC8346999__F7 Signaling Pathways Regulated by UBR Box-Containing E3 Ligases ENSG00000159459 ENSG00000107669 PMC8346999__F1 Signaling Pathways Regulated by UBR Box-Containing E3 Ligases ENSG00000156795 ENSG00000157045 ENSG00000127481 ENSG00000104517 ENSG00000159459 ENSG00000107669 PMC9368818__F9 Transcriptomic Analysis Reveals That Granulocyte Colony-Stimulating Factor Trigger a Novel Signaling Pathway (TAF9-P53-TRIAP1-CASP3) to Protect Retinal Ganglion Cells after Ischemic Optic Neuropathy ENSG00000276463 ENSG00000170855 ENSG00000164305 PMC3342370__F1 Role of autophagy during innate immunity ENSG00000125538 ENSG00000145782 ENSG00000057663 PMC11007101__F2 Therapeutic prospects of nectin-4 in cancer: applications and value ENSG00000291971 PMC4693592__F2 Monocytes from MS patients cluster independently from HV and display enhanced inflammatory pathways PMC10910240__F7 Mechanism of aerobic exercise combined with canagliflozin therapy against ISO-induced CHFCanagliflozin combined with aerobic exercise therapy modulates protein kinase activity ENSG00000003137 ENSG00000128918 ENSG00000140465 PMC11534688__F11 Blestriarene C exerts an inhibitory effect on triple-negative breast cancer through multiple signaling pathways ENSG00000002330 PMC9114368__F8 Illustrative model to show the mechanism of circLIFR in HCC ENSG00000168036 ENSG00000123908 PMC9084550__F2 Signaling pathways and therapeutic approaches in glioblastoma multiforme (Review) ENSG00000071564 ENSG00000138795 ENSG00000134982 ENSG00000140575 ENSG00000138798 ENSG00000168036 ENSG00000146648 PMC4438184__F10 Aldosterone-induced inflammatory responses: role of the ADAM-17/TGFA/EGFR axis and modulation by paricalcitol ENSG00000115415 ENSG00000163235 ENSG00000146648 PMC7424765__F1 Postulated targets of action of B2-adrenergic agonists in DOK7 patients ENSG00000134569 ENSG00000030304 PMC6291477__F2 AHR signaling pathway ENSG00000140465 ENSG00000106546 PMC9368818__F3 Transcriptomic Analysis Reveals That Granulocyte Colony-Stimulating Factor Trigger a Novel Signaling Pathway (TAF9-P53-TRIAP1-CASP3) to Protect Retinal Ganglion Cells after Ischemic Optic Neuropathy ENSG00000120656 ENSG00000166012 ENSG00000102387 ENSG00000187325 ENSG00000147133 ENSG00000197780 ENSG00000276833 ENSG00000135801 ENSG00000137413 ENSG00000115750 ENSG00000165632 ENSG00000166337 ENSG00000130699 ENSG00000198625 PMC10180667__F4 “Components-targets-pathways” network ENSG00000087245 ENSG00000109320 ENSG00000115415 ENSG00000050748 ENSG00000067606 ENSG00000150093 ENSG00000123374 ENSG00000136869 ENSG00000213341 ENSG00000007171 PMC10180667__F5 Effect of FS on toll-like receiver signaling pathway ENSG00000239732 ENSG00000170458 ENSG00000172936 ENSG00000131323 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 ENSG00000143387 PMC6085483__F2 Metabolic reprogramming of cancer cells in the tumor microenvironment (TME) ENSG00000198793 ENSG00000136997 ENSG00000078237 ENSG00000284194 ENSG00000115419 PMC6085483__F1 Metabolism is a key feature of every quiescent cell ENSG00000042832 ENSG00000198793 ENSG00000172005 ENSG00000026103 PMC3581603__F6 Bisphenol-A-induced inactivation of the p53 axis underlying deregulation of proliferation kinetics, and cell death in non-malignant human breast epithelial cells ENSG00000198793 PMC8511446__F5 Assessment of Alveolar Macrophage Dysfunction Using an in vitro Model of Acute Respiratory Distress Syndrome ENSG00000153208 ENSG00000198053 ENSG00000141968 PMC8210610__F8 Major vault protein (MVP) negatively regulates osteoclastogenesis via calcineurin-NFATc1 pathway inhibition ENSG00000100985 ENSG00000131196 ENSG00000143387 PMC4001531__F4 Melanoma NOS1 expression promotes dysfunctional IFN signaling ENSG00000213928 ENSG00000157764 ENSG00000105397 ENSG00000010810 ENSG00000125388 ENSG00000185745 ENSG00000125347 ENSG00000230034 PMC6350303__F9 Molecular mechanism of ZNF326-mediated regulation of Wnt signalling ENSG00000134982 ENSG00000061273 ENSG00000162664 ENSG00000196628 PMC7497304__F1 Models for the interactions between tumor cells and the tumor microenvironment in the brain ENSG00000108691 ENSG00000163599 ENSG00000184371 ENSG00000121807 ENSG00000168610 PMC9375293__F5 Targeting purine metabolism in ovarian cancer ENSG00000228716 ENSG00000198793 PMC5094991__F7 SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline ENSG00000144935 ENSG00000167323 ENSG00000293604 ENSG00000138798 ENSG00000146648 PMC9375293__F1 Targeting purine metabolism in ovarian cancer ENSG00000196839 ENSG00000291814 PMC4877093__F2 IL-4 Causes Hyperpermeability of Vascular Endothelial Cells through Wnt5A Signaling ENSG00000087095 ENSG00000156076 ENSG00000137673 ENSG00000162337 ENSG00000070831 ENSG00000198793 ENSG00000168036 ENSG00000112715 ENSG00000122194 ENSG00000141968 ENSG00000104368 ENSG00000106683 ENSG00000011422 ENSG00000149269 ENSG00000185591 PMC9375293__F2 Targeting purine metabolism in ovarian cancer ENSG00000168610 PMC5584303__F2 Epigenetic integrator UHRF1: on the road to become a universal biomarker for cancer ENSG00000100811 ENSG00000185591 ENSG00000129173 ENSG00000276043 PMC3773757__F6 Summary of the convergence of the E2–ERK and mTORC1 signaling pathways in regulating migration and invasion in LAM patient-derived cells ENSG00000169554 PMC5858571__F4 Schematic of the predicted signalling pathways for HagB-induced MMP production in dendritic cells ENSG00000262406 ENSG00000087245 ENSG00000137673 ENSG00000109320 ENSG00000169047 ENSG00000168036 ENSG00000166670 ENSG00000182621 ENSG00000160691 ENSG00000172216 ENSG00000115415 ENSG00000170458 ENSG00000149968 ENSG00000197943 ENSG00000172936 ENSG00000185591 ENSG00000100985 ENSG00000124181 ENSG00000175104 ENSG00000184216 ENSG00000112486 PMC5555084__F1 Similarities and Distinctions of Cancer and Immune Metabolism in Inflammation and Tumors PMC11491726__F2 Relationship of class I HDACs and NOXs in CVDs ENSG00000111537 ENSG00000171720 ENSG00000115415 ENSG00000086991 ENSG00000196591 ENSG00000079999 PMC10511904__F3 Diagram illustrates how IMD activates various downstream signaling pathways through different CLR/RAMP receptor complexes ENSG00000291507 ENSG00000145321 PMC11727316__F6 Molecular basis of Jusvinza’s mechanism of action on neutrophils ENSG00000104856 ENSG00000162711 ENSG00000284774 ENSG00000147649 ENSG00000105401 ENSG00000163739 ENSG00000130589 ENSG00000150455 ENSG00000166670 ENSG00000127191 ENSG00000273936 ENSG00000273592 ENSG00000180353 ENSG00000151702 ENSG00000065978 ENSG00000124216 ENSG00000082512 ENSG00000189403 ENSG00000136869 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC3100630__F1 EGFR biology ENSG00000146648 PMC7916193__F6 Pathways involved in cutaneous squamous cell carcinoma (cSCC) pathogenesis ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000114315 ENSG00000146648 PMC5122717__F7 Model representing the interaction of Arabidopsis thaliana plants/Brevipalpus mites/CiLV-C ENSG00000105722 ENSG00000136997 ENSG00000123908 PMC9439701__F8 Specific microRNA Profile and Functional Networks for Children with Allergic Asthma ENSG00000163914 ENSG00000145321 PMC7344258__F1 Cysteine is a core player in the cellular metabolism ENSG00000205221 ENSG00000173599 ENSG00000136997 PMC165090__F8 Schematic model for the roles of p120 catenin in the signaling pathways leading to growth factor–induced RhoA stimulation and cell migration ENSG00000291971 ENSG00000160293 PMC8697442__SF1 Novel targeted co-delivery nanosystem for enhanced ovarian cancer treatment via multidrug resistance reversion and mTOR-mediated signaling pathway ENSG00000198793 ENSG00000026508 ENSG00000184207 ENSG00000168610 PMC6523794__F4 PPI network for the upregulated genes in the AMPK signaling pathway ENSG00000135218 ENSG00000288174 ENSG00000110931 ENSG00000159346 ENSG00000285070 ENSG00000105568 ENSG00000079435 PMC11834262__F8 Graphical abstract illustrating the mechanism of SS in treating BC ENSG00000151012 ENSG00000167468 ENSG00000146648 PMC6457213__F7 Model of cytokine-mediated rescue ENSG00000137193 ENSG00000292210 PMC3597489__F4 Conjunctival MicroRNA Expression in Inflammatory Trachomatous Scarring ENSG00000103479 ENSG00000156574 ENSG00000134363 ENSG00000114739 PMC9107479__F1 Extrinsic and intrinsic apoptosis pathways, indicating pharmacological agents and their therapeutic targets ENSG00000111537 ENSG00000168040 PMC9352753__F3 Identification of differentially expressed microRNAs as potential biomarkers for carcinoma ex pleomorphic adenoma ENSG00000157404 ENSG00000105327 ENSG00000160710 ENSG00000108443 ENSG00000171791 ENSG00000102678 ENSG00000285069 ENSG00000172037 ENSG00000245848 ENSG00000157500 ENSG00000159216 ENSG00000078900 ENSG00000163914 ENSG00000150907 ENSG00000136997 ENSG00000077782 ENSG00000139687 ENSG00000155760 ENSG00000140443 ENSG00000282899 ENSG00000162889 ENSG00000087245 ENSG00000143549 ENSG00000101109 ENSG00000187840 ENSG00000076604 ENSG00000048392 ENSG00000110395 ENSG00000164161 ENSG00000175104 ENSG00000146648 ENSG00000130669 ENSG00000047410 ENSG00000185634 ENSG00000149212 ENSG00000117425 ENSG00000198793 ENSG00000115904 ENSG00000168036 ENSG00000150093 ENSG00000099942 ENSG00000112715 ENSG00000118971 ENSG00000164305 ENSG00000137801 ENSG00000175054 ENSG00000112242 ENSG00000130402 ENSG00000104365 ENSG00000005339 ENSG00000109320 ENSG00000174804 ENSG00000173039 ENSG00000134871 ENSG00000168040 ENSG00000073756 ENSG00000168610 ENSG00000221823 ENSG00000149311 ENSG00000066468 ENSG00000113328 ENSG00000172667 ENSG00000148660 ENSG00000102466 ENSG00000134057 ENSG00000135446 ENSG00000177606 ENSG00000104290 ENSG00000171848 ENSG00000143322 ENSG00000128602 PMC8620413__F4 Lipid signaling in cancer ENSG00000131473 ENSG00000135218 ENSG00000198793 ENSG00000169710 ENSG00000285482 ENSG00000153395 ENSG00000146648 ENSG00000123983 ENSG00000026103 PMC4076814__F6 Diagram depicting the role of GPX7 in regulating inflammation in esophageal epithelial cells ENSG00000102871 ENSG00000163739 ENSG00000127191 ENSG00000116157 PMC4729111__F2 Metabolic pathway of l-Phe ENSG00000125166 ENSG00000171759 PMC6862015__F5 Complement lectin pathway activation ENSG00000009724 ENSG00000244414 ENSG00000123843 ENSG00000124491 ENSG00000000971 ENSG00000088926 ENSG00000166278 ENSG00000122194 ENSG00000132693 ENSG00000157131 ENSG00000184500 ENSG00000163631 ENSG00000126218 ENSG00000277571 ENSG00000141480 ENSG00000015285 ENSG00000085265 ENSG00000117335 ENSG00000171560 ENSG00000062485 PMC9223478__F7 Lysine Deprivation Regulates Npy Expression via GCN2 Signaling Pathway in Mandarin Fish (Siniperca chuatsi) ENSG00000128272 ENSG00000144895 PMC5713242__F8 Cilia-dependent mTOR signaling PMC3174756__F5 Ephrin and neurotrophin signaling pathways in primary neurons PMC6461988__F4 Reconstructed key metabolic pathways of Thermoprofundales based on eight MAGs (a) ENSG00000102977 ENSG00000062485 PMC3174756__F6 CDK5 (A) and actin (B) signaling pathway in primary neurons ENSG00000125740 ENSG00000064300 PMC7556532__F8 HER2-mediated enhancement of Ebola virus entry ENSG00000167601 ENSG00000153208 ENSG00000092445 PMC5713242__F3 Cilia-dependent Hedgehog signaling ENSG00000166813 ENSG00000128602 PMC7383016__F1 HR pathway in PTEN-deficient EC cells ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000083093 ENSG00000138798 ENSG00000051180 ENSG00000146648 ENSG00000139618 PMC8752619__F4 Transcriptional alterations in bladder epithelial cells in response to infection with different morphological states of uropathogenic Escherichia coli ENSG00000162711 ENSG00000088888 ENSG00000165660 ENSG00000089041 ENSG00000265972 PMC11635689__S1 Metabolic Pathway of Conversion of 5-ALA to Protoporphyrin IX in Gram-Negative Bacterial Cells ENSG00000066926 ENSG00000126088 ENSG00000256269 PMC7915189__F2 Some examples of signaling pathways involved in OS resistant tumor cells to conventional treatment ENSG00000198793 ENSG00000168036 PMC8262654__F1 Banxia xiexin decoction affects drug sensitivity in gastric cancer cells by regulating MGMT expression via IL-6/JAK/STAT3-mediated PD-L1 activity ENSG00000170430 ENSG00000168610 ENSG00000146648 ENSG00000188389 PMC9603448__F6 Engineered Human Intervertebral Disc Model Inducing Degenerative Microglial Proinflammation ENSG00000108691 ENSG00000169429 PMC10892479__F4 Cytokine storm induced by SARS-CoV-2 proteins (ORF7a, ORF3A, M, and N proteins) mediated by the activation of NF-kB ENSG00000131142 ENSG00000137077 ENSG00000102970 ENSG00000006606 ENSG00000115009 PMC10892479__F5 Illustrates a diagrammatic representation of the intracellular signaling pathways activated by SARS-CoV-2 infection ENSG00000172936 ENSG00000164342 PMC5572672__F2 Inherited and Acquired Disorders of Magnesium Homeostasis ENSG00000159261 ENSG00000164007 ENSG00000113946 ENSG00000036828 PMC10892479__F2 Activation of the NF-kB signaling pathway induced by SARS-Co-V-2 and mediated by RIP/TRAF-dependent pathways or RIP-dependent/TRAF-independent IKKB activation ENSG00000102871 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000184216 PMC10892479__F1 NFKB signaling (canonical and non-canonical) pathways ENSG00000104856 ENSG00000186716 ENSG00000173039 ENSG00000111321 PMC7178465__F2 Danger-Associated Molecular Pattern (DAMP) binds to the Pattern Recognition Receptors (PRRs) expressed on the cytosol or in innate immune cell membranes ENSG00000162711 PMC7178465__F3 Increase of intracellular calcium activates neural nitric oxide synthase (nNOS), causing increased NO levels ENSG00000139180 ENSG00000142082 PMC8197470__F1 Advantages and Disadvantages of Different Treatment Methods in Achondroplasia: A Review ENSG00000152266 ENSG00000173786 PMC10796102__F6 Action of cerebral lymphatic system in brain diseases due to impaired renal function ENSG00000280962 ENSG00000138166 ENSG00000291431 ENSG00000132478 ENSG00000106546 PMC10796102__F4 Binding of CCL19/CCL21 to CCR7 activated signaling pathways in tumor cells, including PI3/Akt, MAPK/ERK and Jak/STAT, which enhanced the expression of VEGF-C and thus promoted lymphangiogenesis ENSG00000137077 ENSG00000126353 ENSG00000150630 PMC10796102__F5 Communication between the gastrointestinal tract and cerebral lymphatic system is mediated directly and indirectly by immune, neural and endocrine pathways ENSG00000162711 ENSG00000171885 PMC10796102__F3 Possible mechanisms of co-occurring neuroinflammatory response and brain edema in patients with hepatic encephalopathy and potential therapeutic targets for hepatic encephalopathy ENSG00000171885 ENSG00000150630 PMC7123501__F3 Simplified scenario model illustrating the intrinsic and extrinsic apoptotic pathways ENSG00000132906 ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC7123501__F4 Simplified scenario model of the necroptotic pathway ENSG00000137275 ENSG00000137033 ENSG00000102871 ENSG00000163739 ENSG00000125538 ENSG00000189403 ENSG00000136869 ENSG00000168404 ENSG00000127191 ENSG00000285379 ENSG00000164342 PMC3904234__F1 Interleukin-17 (IL-17) and IL-17 receptor family members and their biological roles ENSG00000082512 ENSG00000056736 ENSG00000175104 ENSG00000127191 ENSG00000163702 PMC8535311__F2 Genetic and Genomic Pathways of Melanoma Development, Invasion and Metastasis ENSG00000134982 ENSG00000168036 PMC6617489__F5 Lipotoxicity of VLDLs on mediating maladaptation of calcium regulation to derangement of sarcomere proteins in atrial myopathy ENSG00000167323 ENSG00000293604 PMC8535311__F3 Genetic and Genomic Pathways of Melanoma Development, Invasion and Metastasis ENSG00000198742 PMC4380664__F3 Pharmacological targets and signaling cascades proposed to be important in mediating synaptic plasticity underlying extinction ENSG00000291971 ENSG00000163914 ENSG00000145321 ENSG00000139890 PMC6061795__F8 An Orc1-2-centered network of DNA damage response in S ENSG00000115942 ENSG00000135336 ENSG00000091651 PMC7251178__F1 TGFB and BMP-7 pathways ENSG00000170365 ENSG00000163914 PMC7251178__F2 Inflammasome complex -dependent and -independent pathways involved in EMT ENSG00000162711 ENSG00000150782 ENSG00000172936 PMC6365421__F1 Chaperone mediated autophagy mechanism ENSG00000081913 ENSG00000131095 PMC6524193__F5 Functional prediction of key lncRNA-mRNAs network ENSG00000108515 ENSG00000008513 ENSG00000050748 ENSG00000159322 ENSG00000163755 ENSG00000184956 ENSG00000154582 ENSG00000100714 ENSG00000172992 ENSG00000276051 ENSG00000106603 ENSG00000185269 ENSG00000187210 PMC4081729__F5 Modification of the Nrf-2 and NFKB signaling pathways by phytochemicals upregulates antioxidant and detoxification enzymes and suppresses inflammation ENSG00000178573 ENSG00000171791 ENSG00000079999 PMC3171706__F3 G2/M transition and G2/M checkpoint induction ENSG00000149311 ENSG00000175054 ENSG00000166851 ENSG00000276876 PMC8250230__F5 An Integrative in silico Drug Repurposing Approach for Identification of Potential Inhibitors of SARS‐CoV‐2 Main Protease ENSG00000108691 ENSG00000130234 ENSG00000125538 ENSG00000169429 PMC3171706__F1 G1/S transition and G1/S checkpoint induction ENSG00000149311 ENSG00000094804 ENSG00000135446 ENSG00000167513 ENSG00000123374 ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000166508 ENSG00000093009 PMC2915738__F7 Metalloproteinase-dependent cross-talk between the PDGFRB and the EGFR/ERK1/2 signaling pathway ENSG00000146648 PMC8346230__F5 Representative diagram of the molecular interactions among AJUBA, CDH4, and CTNNB1 ENSG00000129474 ENSG00000179242 ENSG00000168036 PMC8317057__F4 Pathogenic Features of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Possible Mechanisms for Immune Evasion? ENSG00000108691 ENSG00000105397 ENSG00000110713 ENSG00000172936 ENSG00000185591 ENSG00000168610 ENSG00000121060 ENSG00000164342 PMC3995130__F2 mTOR Signaling in Cardiac Physiology and Disease ENSG00000155792 PMC9050958__F8 Interferon-gamma Induces Melanogenesis Via Post-Translational Regulation of Tyrosinase ENSG00000159128 ENSG00000111537 ENSG00000049130 ENSG00000115415 ENSG00000168036 ENSG00000027697 ENSG00000080166 ENSG00000107165 PMC3131090__F1 Negative regulation of the autophagy pathway ENSG00000177169 ENSG00000198793 ENSG00000144848 ENSG00000145782 PMC5139348__F3 PI3K Pathway in B Cell Metabolism ENSG00000122986 ENSG00000112182 PMC5139348__F1 PI3K Pathway in B Cell Metabolism ENSG00000131473 ENSG00000150907 ENSG00000186716 ENSG00000159399 PMC5139348__F2 PI3K Pathway in B Cell Metabolism ENSG00000131473 ENSG00000026103 PMC5753586__F2 Non-canonical NFKB pathway in immunity and inflammation ENSG00000104856 ENSG00000183735 ENSG00000264522 ENSG00000142405 ENSG00000131323 ENSG00000127191 PMC5753586__F3 Non-canonical NFKB pathway in immunity and inflammation ENSG00000186716 ENSG00000145321 PMC11871115__F7 Mechanism of action of polyphenols in Alzheimer's disease (AD) through modulation of the WBC signaling pathway ENSG00000134982 ENSG00000168036 PMC8360640__F2 Cellular and molecular mechanisms of perineural invasion of pancreatic ductal adenocarcinoma ENSG00000019991 ENSG00000107562 ENSG00000100985 ENSG00000168610 ENSG00000121966 ENSG00000064300 PMC11695688__F9 Simple signaling pathway diagram ENSG00000172667 ENSG00000150093 PMC3069928__F1 Biological actions of IGF-1 are mediated by IGF-1R and modulated by IGFBPs ENSG00000169047 PMC2386284__F5 The mechanism of retinoic acid stimulation of NIS expression by modifying signal transduction pathways in breast cancer and thyroid cells, based on the results of the inhibitor studies ENSG00000169047 PMC8126715__F1 KRAS-Mutant Non-Small Cell Lung Cancer: An Emerging Promisingly Treatable Subgroup ENSG00000070831 ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC5007117__F2 Schematic representing intrinsic and extrinsic apoptosis initiation ENSG00000120868 PMC8979796__F4 Metabolic pathways regulating the development and non-genomic heritable traits of germ cells ENSG00000284320 PMC8576268__F1 Deciphering glial scar after spinal cord injury ENSG00000168040 ENSG00000143258 PMC8891573__F1 Dysregulation of the Nitric Oxide/Dimethylarginine Pathway in Hypoxic Pulmonary Vasoconstriction—Molecular Mechanisms and Clinical Significance ENSG00000113492 PMC6250734__F8 Diagrammatic sketch of molecular mechanism ENSG00000134982 ENSG00000168036 PMC8102268__F4 Study of the differential expression profiles of Keshan disease lncRNA/mRNA genes based on RNA-seq ENSG00000145604 ENSG00000149311 ENSG00000087095 ENSG00000127528 ENSG00000111816 ENSG00000140743 PMC3938550__F5 Comparative Genomic and Transcriptomic Analyses of LNCaP and C4-2B Prostate Cancer Cell Lines ENSG00000110799 ENSG00000291971 ENSG00000189056 ENSG00000171608 PMC3407377__F3 TGFB signaling via TAK1 pathway: Role in kidney fibrosis PMC3407377__F2 TGFB signaling via TAK1 pathway: Role in kidney fibrosis ENSG00000175104 PMC6165716__F8 Schematic showing PDK4 as a checkpoint in NFKB/TNF-mediated apoptosis ENSG00000132906 ENSG00000164305 PMC8566352__F2 Plasmalogens and Chronic Inflammatory Diseases ENSG00000018510 ENSG00000197601 PMC3912139__F6 GNAS Mutation Found in Pancreatic Intraductal Papillary Mucinous Neoplasms Induces Drastic Alterations of Gene Expression Profiles with Upregulation of Mucin Genes ENSG00000291363 ENSG00000087460 ENSG00000293532 PMC2193446__F7 The hypothesized biochemical pathway responsible for the hyperproliferative phenotype of Nf1 +/− mast cells in response to SCF ENSG00000124102 ENSG00000149269 PMC8514721__F1 Microbiota and Colorectal Cancer: From Gut to Bedside ENSG00000150782 ENSG00000168610 PMC4570227__F4 Metabolic pathways with compounds that can be used as molecular imaging probes for HP MRI ENSG00000173599 ENSG00000080166 ENSG00000115419 ENSG00000062485 PMC4498995__F2 Metabolism and transport of acetaminophen in the liver at highly toxic doses ENSG00000196502 ENSG00000140505 ENSG00000130649 ENSG00000196620 ENSG00000118777 ENSG00000023839 PMC4367189__F2 Signal transduction pathways from the cell membrane to the nucleus discussed in this article ENSG00000160973 ENSG00000157933 ENSG00000198793 ENSG00000185591 PMC6466611__F6 Cyclin C-Cdk8/19/3 inhibit the Notch pathway by phosphorylating the Notch intracellular fragment (NICD) and promoting its degradation in leukemic T cells ENSG00000250506 ENSG00000132964 PMC4448604__F2 Drosophila Hippo pathway ENSG00000132471 ENSG00000142192 PMC8443079__F2 Regulation of renin in the collecting ducts ENSG00000167580 ENSG00000143839 PMC5289082__F5 Toll-like receptor-mediated actions ENSG00000172936 ENSG00000131323 ENSG00000175104 PMC7708378__F4 GHR activation and signaling ENSG00000169047 ENSG00000276051 PMC8021480__F1 Schematics of GSC niches and the redox signaling at play ENSG00000133937 PMC7969799__F1 The molecular mechanism of TRP channel-mediated pathogenesis of neurological disorders: (A) Alzheimer’s disease, (B) Parkinson’s disease, (C) Huntington’s disease, (D) Amyotrophic lateral sclerosis, and (E) epilepsy ENSG00000124102 ENSG00000092439 ENSG00000133107 ENSG00000144935 ENSG00000069018 ENSG00000198793 ENSG00000072315 ENSG00000196689 PMC7413060__F1 Innate immunity in the initial phase of infection ENSG00000162711 ENSG00000125538 ENSG00000254415 PMC12122306__F1 Insulin signaling pathway in cardiovascular changes in GDM ENSG00000169047 ENSG00000198793 PMC4982242__F1 Non-activated canonical Wnt signaling pathway and the drug targeted components ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000173273 PMC4982242__F2 Activated canonical Wnt signaling pathway and the drug targeted components ENSG00000281324 ENSG00000162337 ENSG00000102312 ENSG00000106483 PMC5662193__F6 Cytotoxic Vibrio T3SS1 Rewires Host Gene Expression to Subvert Cell Death Signaling and Activate Cell Survival Networks ENSG00000145632 ENSG00000128016 ENSG00000119508 ENSG00000165030 ENSG00000163739 ENSG00000130522 ENSG00000186480 ENSG00000127528 ENSG00000103522 ENSG00000162772 ENSG00000178726 ENSG00000136826 ENSG00000159167 ENSG00000159200 ENSG00000117525 ENSG00000172216 ENSG00000122691 ENSG00000118515 ENSG00000169429 ENSG00000152137 ENSG00000164400 ENSG00000128342 ENSG00000157514 ENSG00000084093 ENSG00000137834 ENSG00000081041 ENSG00000030419 ENSG00000100906 ENSG00000108342 ENSG00000221869 ENSG00000166278 ENSG00000139211 ENSG00000274746 ENSG00000073756 ENSG00000129250 ENSG00000108691 ENSG00000143507 ENSG00000177606 ENSG00000156427 ENSG00000258643 PMC3628101__F1 The novel NRP2A6B1-FAK-RAS-GLI1 axis involved in the regulation of tumour initiating cells in breast cancer ENSG00000168283 ENSG00000118257 PMC5483433__F2 The potential roles of miR-M4-5p and miR-K12-11 in regulating the TGFB signaling pathway and promoting tumorigenesis ENSG00000049323 ENSG00000105329 PMC2565686__F6 Merger of the interaction maps for the three human proteins ING1, MEKK, and p38a (p38MAPK) based on empirical data retrieved from the STRING database ENSG00000111057 ENSG00000120875 ENSG00000174744 ENSG00000134308 ENSG00000157601 ENSG00000170890 ENSG00000136997 ENSG00000196498 ENSG00000139687 ENSG00000089022 ENSG00000140464 ENSG00000162889 ENSG00000170027 ENSG00000065559 ENSG00000116717 ENSG00000101224 ENSG00000153487 ENSG00000156970 ENSG00000143507 ENSG00000132646 ENSG00000107485 ENSG00000164086 ENSG00000135218 ENSG00000280962 ENSG00000291603 ENSG00000070831 ENSG00000196591 ENSG00000099860 ENSG00000162302 ENSG00000164305 ENSG00000179295 ENSG00000125538 ENSG00000056558 ENSG00000130222 ENSG00000162521 ENSG00000185591 ENSG00000169375 ENSG00000101189 ENSG00000105204 ENSG00000158050 ENSG00000182718 ENSG00000005339 ENSG00000173039 ENSG00000150764 ENSG00000197045 ENSG00000081189 ENSG00000164105 ENSG00000185386 ENSG00000120899 ENSG00000115415 ENSG00000010810 ENSG00000177606 ENSG00000070770 ENSG00000145649 ENSG00000178028 ENSG00000129152 ENSG00000123268 PMC8699889__F10 Prognostic and Genomic Analysis of Proteasome 20S Subunit Alpha (PSMA) Family Members in Breast Cancer ENSG00000149311 ENSG00000175054 ENSG00000002330 ENSG00000175193 ENSG00000111837 ENSG00000121966 PMC11274491__F7 Proposed scheme for the anti-angiogenic activities of PZ-DHA ENSG00000112576 ENSG00000070831 ENSG00000198793 ENSG00000163914 PMC8699889__F11 Prognostic and Genomic Analysis of Proteasome 20S Subunit Alpha (PSMA) Family Members in Breast Cancer ENSG00000145604 ENSG00000068028 ENSG00000149311 ENSG00000175054 ENSG00000134982 ENSG00000113520 ENSG00000123374 ENSG00000166851 ENSG00000117399 PMC8699889__F12 Prognostic and Genomic Analysis of Proteasome 20S Subunit Alpha (PSMA) Family Members in Breast Cancer ENSG00000213658 ENSG00000186716 ENSG00000163914 ENSG00000116096 PMC7197128__F6 FAT4 silencing promotes epithelial-to-mesenchymal transition and invasion via regulation of YAP and Beta-catenin activity in ovarian cancer ENSG00000168036 ENSG00000133740 PMC7427672__F1 OI genes involved in collagen biosynthesis and maintenance of bone homeostasis ENSG00000166794 ENSG00000113140 ENSG00000206013 ENSG00000117899 ENSG00000168487 ENSG00000012174 ENSG00000125084 ENSG00000112773 ENSG00000117385 ENSG00000095209 ENSG00000170275 ENSG00000291837 ENSG00000171759 ENSG00000108821 ENSG00000152952 PMC8125483__F1 Insights on the Functional Role of Beta-Glucans in Fungal Immunity Using Receptor-Deficient Mouse Models ENSG00000104856 ENSG00000162711 ENSG00000150782 ENSG00000111537 ENSG00000085117 ENSG00000187796 PMC5680920__F8 Schematic representation of the regulatory mechanism about PLOD2 was summarized ENSG00000163235 ENSG00000138798 ENSG00000129514 ENSG00000152952 ENSG00000146648 PMC5010449__F3 Avoidance and subversion of eukaryotic homeostatic autophagy mechanisms by bacterial pathogens ENSG00000177169 ENSG00000057663 PMC12226309__F1 cGAS-STING pathway as a promising target for digestive diseases: insights from natural plant products ENSG00000183735 ENSG00000164430 PMC2719424__F8 DUOX1 involvement in TLR-mediated IL-8 production in response to bacterial stimuli ENSG00000137857 ENSG00000163235 ENSG00000291971 ENSG00000169429 ENSG00000146648 PMC12226309__F3 cGAS-STING pathway as a promising target for digestive diseases: insights from natural plant products ENSG00000164430 ENSG00000106546 PMC12226309__F4 cGAS-STING pathway as a promising target for digestive diseases: insights from natural plant products ENSG00000162711 ENSG00000164430 PMC9163066__F8 Schematic model for the circSCAF8-miR-140-3p/miR-335-LIF pathway ENSG00000128342 ENSG00000168610 PMC8395722__F2 Synthetic mRNAs; Their Analogue Caps and Contribution to Disease ENSG00000171791 PMC9008121__F2 Targeting non-coding RNAs to overcome cancer therapy resistance ENSG00000167601 ENSG00000169245 ENSG00000105664 ENSG00000065978 ENSG00000151012 ENSG00000141448 ENSG00000178999 ENSG00000131747 ENSG00000099246 ENSG00000110046 ENSG00000253729 ENSG00000123908 PMC6351746__F1 Biochemical pathways of R ENSG00000105697 PMC8648605__F6 Norcholic Acid Promotes Tumor Progression and Immune Escape by Regulating Farnesoid X Receptor in Hepatocellular Carcinoma PMC6476693__F1 Metabolic profiles influence macrophage inflammatory status ENSG00000135218 ENSG00000168610 PMC12118952__F3 LDH in the occurrence and development of liver cancer PMC7085230__F7 Mechanisms for the inhibition of SMAD2/SMAD3 and the activation of TET1 signaling by MSTN mutation ENSG00000111049 ENSG00000122180 PMC5352210__F5 Unconjugated secondary bile acids activate the unfolded protein response and induce golgi fragmentation via a src-kinase-dependant mechanism ENSG00000128272 ENSG00000162772 ENSG00000146648 PMC7456869__F4 SARS-CoV-2 in the RAAS pathway ENSG00000175054 ENSG00000183695 ENSG00000130234 PMC7456869__F5 SARS-CoV-2 in the complement system ENSG00000166278 ENSG00000236625 PMC8965836__F9 Parathyroid Hormone Promotes Human Umbilical Vein Endothelial Cell Migration and Proliferation Through Orai1-Mediated Calcium Signaling ENSG00000152266 ENSG00000167323 ENSG00000293604 ENSG00000108821 ENSG00000131196 PMC7456869__F6 SARS-CoV-2 in coagulation ENSG00000130234 ENSG00000122194 PMC3081520__F2 Autophagy in cigarette smoke-induced chronic obstructive pulmonary disease ENSG00000126775 ENSG00000198793 ENSG00000005893 ENSG00000182858 ENSG00000057663 PMC5653461__F1 Progesterone Receptors (PR) Mediate STAT Actions: PR and Prolactin Receptor Signaling Crosstalk in Breast Cancer Models ENSG00000125084 ENSG00000113494 PMC3081520__F4 Autophagy in cigarette smoke-induced chronic obstructive pulmonary disease ENSG00000126775 ENSG00000168040 ENSG00000145782 ENSG00000057663 PMC8943211__F7 Monoacylglycerol acyltransferase pathway contributes to triacylglycerol synthesis in HepG2 cells ENSG00000042832 ENSG00000168282 ENSG00000198670 PMC5041017__F1 IFN signalling pathways induced by IFNA/B and IFNG (see text for details) ENSG00000159128 ENSG00000105397 ENSG00000115415 ENSG00000027697 ENSG00000142166 PMC4915141__F7 The biologic role of TRIM11 in lung cancer ENSG00000154370 ENSG00000132646 PMC5593690__F1 PI3K/Akt pathway: a critical player in intervertebral disc degeneration ENSG00000002330 ENSG00000155792 PMC5593690__F2 The PI3K/Akt pathway: a critical player in intervertebral disc degeneration ENSG00000125398 ENSG00000198793 ENSG00000128928 PMC8620733__F9 CDK4 in the Pathogenesis of Pancreatic Cancer ENSG00000132906 ENSG00000288318 ENSG00000002330 ENSG00000135446 ENSG00000051180 ENSG00000168610 ENSG00000122008 ENSG00000139618 PMC8122967__F1 PARP Enzyme Family and the Hallmarks of Cancer Part 1. Cell Intrinsic Hallmarks ENSG00000023445 ENSG00000110330 ENSG00000118518 ENSG00000102871 ENSG00000171791 ENSG00000168040 ENSG00000138617 ENSG00000127191 ENSG00000176153 ENSG00000197063 ENSG00000103479 ENSG00000134853 ENSG00000120868 ENSG00000096717 ENSG00000227345 ENSG00000150630 PMC8122967__F2 PARP Enzyme Family and the Hallmarks of Cancer Part 1. Cell Intrinsic Hallmarks ENSG00000080345 ENSG00000291996 ENSG00000139618 ENSG00000149311 ENSG00000012048 ENSG00000169621 ENSG00000134574 ENSG00000041880 ENSG00000051180 ENSG00000128513 ENSG00000227345 ENSG00000136936 ENSG00000138385 PMC8122967__F3 PARP Enzyme Family and the Hallmarks of Cancer Part 1. Cell Intrinsic Hallmarks ENSG00000143799 ENSG00000177169 ENSG00000198793 ENSG00000291803 ENSG00000169710 ENSG00000164327 ENSG00000178685 ENSG00000197063 ENSG00000065833 ENSG00000134086 ENSG00000107854 ENSG00000096717 ENSG00000115419 ENSG00000159399 ENSG00000227345 ENSG00000173273 PMC3057977__F3 Comparison of Expression Profiles in Ovarian Epithelium In Vivo and Ovarian Cancer Identifies Novel Candidate Genes Involved in Disease Pathogenesis ENSG00000134982 ENSG00000117399 ENSG00000062485 ENSG00000132341 PMC1186689__F1 Interferon-Gamma-dependent tyrosine phosphorylation of MEKK4 via Pyk2 is regulated by annexin II and SHP2 in keratinocytes ENSG00000111537 PMC8620733__F8 CDK4 in the Pathogenesis of Pancreatic Cancer ENSG00000145604 ENSG00000118007 ENSG00000101972 ENSG00000108055 ENSG00000170458 ENSG00000132646 ENSG00000115942 ENSG00000123374 ENSG00000091651 ENSG00000277273 ENSG00000166508 PMC7045041__F1 Possible central and peripheral effects of asprosin ENSG00000136869 ENSG00000166147 PMC7911844__F2 Biosynthetic pathway of the mcm5s2U modification ENSG00000167118 PMC4601503__F3 Binding proteins ENSG00000198793 PMC2988681__F2 Programming anoikis induction ENSG00000291971 ENSG00000168040 ENSG00000026103 PMC6640697__F13 In vivo safety evaluations of MOv18 IgE ENSG00000120899 ENSG00000150093 ENSG00000273686 PMC5048206__F2 Schematic depicting the major proinflammatory glial-mediated changes to inhibitory synapses within the spinal dorsal horn that facilitate central sensitization ENSG00000108691 ENSG00000111537 ENSG00000125538 PMC8053610__F7 The underlying mechanism of calycosin effects on signaling pathways and the induction of apoptosis in GC cells ENSG00000002330 ENSG00000135446 ENSG00000168036 ENSG00000123374 ENSG00000105810 PMC8092118__F3 5-Fluorouracil: A Narrative Review on the Role of Regulatory Mechanisms in Driving Resistance to This Chemotherapeutic Agent ENSG00000140564 ENSG00000168214 ENSG00000283780 ENSG00000128917 ENSG00000148400 ENSG00000074181 ENSG00000100985 ENSG00000090932 PMC8092118__F1 5-Fluorouracil: A Narrative Review on the Role of Regulatory Mechanisms in Driving Resistance to This Chemotherapeutic Agent ENSG00000087095 ENSG00000138795 ENSG00000281324 ENSG00000116729 ENSG00000162337 ENSG00000134982 ENSG00000133067 ENSG00000168036 ENSG00000118777 ENSG00000168283 ENSG00000183579 ENSG00000026508 ENSG00000108375 ENSG00000083799 PMC2756491__F8 PPARA/p16INK4a Pathway inhibits Vascular Smooth Muscle Cell Proliferation by repressing Cell Cycle-dependent Telomerase Activation ENSG00000135446 ENSG00000164362 ENSG00000105810 PMC4047132__F2 Cellular functions of proteins commonly mutated in uveal melanoma ENSG00000012048 ENSG00000163930 ENSG00000115524 ENSG00000171456 PMC5595793__F1 Schematics of alcohol production via the iterative ketoacid elongation ENSG00000039537 PMC4477219__F2 Nrf2/ARE pathway and cAMP second messenger system together are the key regulators of cellular antioxidant defence ENSG00000096717 ENSG00000079999 PMC8586683__F6 Chemokine C‐C motif ligand 21 synergized with programmed death‐ligand 1 blockade restrains tumor growth ENSG00000137077 ENSG00000126353 PMC4073609__F2 By activating Sirt1, NAD+ conjoins two feedback loops necessary for cross-talk between the circadian clock and metabolite production ENSG00000105835 ENSG00000157064 ENSG00000173614 ENSG00000096717 PMC9529885__F7 Diesel exhaust particles induce human umbilical vein endothelial cells apoptosis by accumulation of autophagosomes and caspase-8 activation ENSG00000079950 ENSG00000099940 ENSG00000118640 ENSG00000136874 PMC6850919__F8 Resveratrol (Res)‐mediated suppression of ALI through STAT3/SOCS3 signalling ENSG00000096717 ENSG00000168610 PMC9426234__F1 HK2: a potential regulator of osteoarthritis via glycolytic and non-glycolytic pathways ENSG00000160883 ENSG00000159399 PMC8508942__F2 Vascular Smooth Muscle Cell Phenotype Switching in Arteriogenesis ENSG00000186260 ENSG00000196588 ENSG00000138798 ENSG00000163914 ENSG00000141052 ENSG00000136826 PMC7076804__F5 Cross-talk between activation of the DDR and the IR upon infection with genotoxin-producing bacteria ENSG00000149311 ENSG00000145839 ENSG00000125538 ENSG00000162892 PMC3080846__F1 Innate Immune Sensing of DNA ENSG00000239732 ENSG00000088888 ENSG00000163568 ENSG00000168036 ENSG00000172936 ENSG00000131323 PMC8431111__F10 circBTBD7 Promotes Immature Porcine Sertoli Cell Growth through Modulating miR-24-3p/MAPK7 Axis to Inactivate p38 MAPK Signaling Pathway ENSG00000166484 ENSG00000277222 ENSG00000123908 PMC3246677__F2 Regulation of viperin expression ENSG00000088888 ENSG00000136869 ENSG00000107201 ENSG00000125347 ENSG00000276561 ENSG00000164342 PMC8904240__F7 Punicalagin promotes autophagic degradation of human papillomavirus E6 and E7 proteins in cervical cancer through the ROS-JNK-BCL2 pathway ENSG00000126775 ENSG00000196455 ENSG00000171791 ENSG00000057663 PMC2911411__F3 Network analysis of BAL proteome changes under baseline conditions ENSG00000277571 ENSG00000081051 ENSG00000264424 PMC6603210__F1 IL-1F family signaling complexes ENSG00000137033 ENSG00000136696 ENSG00000136694 ENSG00000172936 ENSG00000115594 ENSG00000137496 PMC8733588__F2 What Happens to the Immune Microenvironment After PD-1 Inhibitor Therapy? ENSG00000108691 ENSG00000089692 PMC7031046__F6 Identification of cancer driver genes based on nucleotide context ENSG00000182901 ENSG00000104884 ENSG00000163930 ENSG00000157404 ENSG00000134982 ENSG00000198793 ENSG00000181555 ENSG00000116251 ENSG00000121879 ENSG00000160007 ENSG00000065833 ENSG00000134086 ENSG00000186575 ENSG00000163914 ENSG00000087842 ENSG00000177084 ENSG00000139687 ENSG00000198286 ENSG00000109670 ENSG00000118058 ENSG00000157764 ENSG00000137193 ENSG00000273686 ENSG00000143631 ENSG00000149311 ENSG00000066468 ENSG00000101972 ENSG00000224320 ENSG00000115524 ENSG00000183337 ENSG00000172936 ENSG00000146648 ENSG00000127948 ENSG00000102974 ENSG00000189079 PMC3360100__F3 Examples of signal transduction pathways in astroglial cells following P2Y1R activation ENSG00000132906 ENSG00000168610 ENSG00000164305 PMC3360100__F2 Examples of signal transduction pathways in astroglial cells following P2X7R activation ENSG00000163914 ENSG00000110218 PMC5125043__F1 The inflammatory response to extracorporeal membrane oxygenation (ECMO) ENSG00000039537 ENSG00000113600 ENSG00000125538 PMC4092924__F2 Schematic illustration of the current working hypothesis on IFNT signaling in ovine uterine stroma and uterine glandular epithelium compared to uterine luminal (LE) and supferficial glandular (sGE) epithelia ENSG00000169245 ENSG00000187608 ENSG00000105397 ENSG00000003989 ENSG00000115415 ENSG00000146678 ENSG00000168310 ENSG00000273686 ENSG00000125347 PMC4092924__F3 Proposed model of IFNT signal transduction cascades that is independent of STAT1 in the ovine uterine LE and sGE ENSG00000198793 ENSG00000168310 ENSG00000125347 PMC3495805__F1 Functional roles of pluripotency transcription factors in mesenchymal stem cells PMC3133882__F4 Diverse mechanisms for activation of Wnt signalling in the ovarian tumour microenvironment ENSG00000134982 ENSG00000198670 PMC9033251__F1 How compensatory mechanisms and adaptive rewiring have shaped our understanding of therapeutic resistance in cancer ENSG00000171105 ENSG00000135446 ENSG00000106070 ENSG00000198793 ENSG00000169047 ENSG00000164327 ENSG00000105810 ENSG00000146648 PMC11396105__F11 Schematic diagram reveals key genes and pathways involved in the heterosis formation of EFT ENSG00000137273 ENSG00000259207 ENSG00000167114 ENSG00000276559 ENSG00000163453 ENSG00000112715 ENSG00000076555 ENSG00000130304 ENSG00000105429 ENSG00000134824 ENSG00000141753 ENSG00000115138 ENSG00000285482 ENSG00000140284 ENSG00000175336 ENSG00000114279 ENSG00000115461 ENSG00000123689 ENSG00000026103 PMC8328821__F3 NUMB/NUMB isoforms in cancer stem cells ENSG00000002330 ENSG00000116717 ENSG00000133961 ENSG00000132964 ENSG00000184916 ENSG00000114315 ENSG00000137845 PMC8105388__F3 Transcriptome of wild-type and immortalized corneal epithelial cells ENSG00000094880 ENSG00000118007 ENSG00000108055 ENSG00000134982 ENSG00000112118 ENSG00000205250 ENSG00000091651 ENSG00000277273 ENSG00000117399 ENSG00000166508 ENSG00000093009 ENSG00000145604 ENSG00000175054 ENSG00000101972 ENSG00000100473 ENSG00000115942 ENSG00000123374 PMC11396105__F10 Interaction network of lipid metabolism-associated pathways and key genes ENSG00000177465 ENSG00000135218 ENSG00000276559 ENSG00000050748 ENSG00000091409 ENSG00000163453 ENSG00000076555 ENSG00000121879 ENSG00000062282 ENSG00000157184 ENSG00000105429 ENSG00000115138 ENSG00000285482 ENSG00000115461 PMC4122637__F3 PharmGKB summary: uric acid-lowering drugs pathway, pharmacodynamics ENSG00000124568 ENSG00000197901 ENSG00000124564 ENSG00000168065 ENSG00000168961 ENSG00000172940 ENSG00000118777 ENSG00000109667 PMC4400837__F2 RAS trafficking pathway ENSG00000116237 PMC5872601__F1 The signalling pathways of UPR ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC9255486__F3 Mitochondria: intracellular sentinels of infections ENSG00000164430 ENSG00000088888 ENSG00000169136 ENSG00000125656 PMC6073339__F2A Involvement of PPARs in the Peculiar Energetic Metabolism of Tumor Cells ENSG00000168036 ENSG00000175567 ENSG00000026103 PMC11779860__F6 Mechanistic diagram of HF against HAPH ENSG00000132646 ENSG00000105810 PMC5448185__F1 The role of ITSN1 in Reelin signaling in the forebrain ENSG00000166278 ENSG00000173406 PMC7982600__F1 Known signaling pathways involved in FGF21 expression from skeletal muscle ENSG00000144895 ENSG00000105550 ENSG00000129152 PMC5833071__F7 CXCL12 stimulates expression of connective tissue growth factor ENSG00000107562 ENSG00000121966 PMC5114407__F7 Cell-specific Kaiso (ZBTB33) Regulation of Cell Cycle through Cyclin D1 and Cyclin E1 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC6322655__F1 Immune responses of macrophages and dendritic cells regulated by mTOR signaling PMC9471422__F2 Contribution of the gut-liver axis to the immune signaling pathway of NAFLD ENSG00000162711 ENSG00000170458 ENSG00000167910 ENSG00000150907 ENSG00000172936 ENSG00000136869 ENSG00000117707 ENSG00000096717 PMC6885373__F1 DNA Replication Inhibitor Geminin and Retinoic Acid Signaling Participate in Complex Interactions Associated With Pluripotency ENSG00000136997 ENSG00000112312 PMC4865369__F7 Model for wntP-2, ptk7 and ndl-3 in control of patterning ENSG00000112655 ENSG00000155760 ENSG00000157240 PMC6073339__F1A Involvement of PPARs in the Peculiar Energetic Metabolism of Tumor Cells ENSG00000291971 ENSG00000127528 ENSG00000026103 PMC9368912__F2 Epidemiology and Molecular Biology of HPV Variants in Cervical Cancer: The State of the Art in Mexico ENSG00000168036 ENSG00000168646 PMC2413267__F1 Wnt Signaling and Skeletal Development ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9048904__F6 Thirty years of resistance: Zig-zag through the plant immune system ENSG00000171735 ENSG00000151461 ENSG00000108509 PMC6663587__F7 Signaling cascade in RANKL-RANK induced osteoclastogenesis: A model of IRF8-mediated regulation of osteoclast differentiation ENSG00000170909 ENSG00000204103 ENSG00000004948 ENSG00000140968 ENSG00000164935 ENSG00000102575 ENSG00000175104 ENSG00000131196 ENSG00000143387 PMC2430594__F1 Cartoon of two of the most promising DNA repair pathways for cancer therapeutics ENSG00000149311 ENSG00000175054 ENSG00000132646 PMC10921469__F9 TRPM4 and TRPM5 mediate Na+ influx upon stimulation with bitter compounds and carbachol (acetylcholine) in parietal cells from the cell line HGT-1 as major signaling pathway ENSG00000070985 ENSG00000166278 PMC8616751__F2 Therapeutic targeting opportunities in cancer cases with RSPO overactivation ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000133067 ENSG00000102312 ENSG00000183579 ENSG00000108375 PMC8616751__F1 Canonical Wnt pathway and the potentiating effect of RSPO ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000133067 ENSG00000177606 ENSG00000183579 ENSG00000108375 PMC2952500__F1 Schematic diagram showing the results of ras activation by Grb2 ENSG00000124102 ENSG00000141448 ENSG00000138798 ENSG00000132646 PMC6589336__F2 Synthetic Biology Tools for Programming Cell and Tissue ENSG00000177455 ENSG00000138336 PMC4232466__F2 Inflammophilic character of the periodontitis-associated microbiota ENSG00000174125 ENSG00000039537 ENSG00000198742 ENSG00000172005 ENSG00000172936 PMC4237952__F4 Complement-induced inflammation pathway: an important mediator of neuroinflammatory processes from M4 onwards ENSG00000140678 ENSG00000169896 ENSG00000259207 ENSG00000159189 ENSG00000236625 PMC4314091__F1 Unusual Case of Porcupine ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000167074 ENSG00000108375 PMC6326012__F1 The metabolic pathway for vitamin D (Adapted/modified from Schlingmann et al ENSG00000111012 ENSG00000118972 ENSG00000152266 ENSG00000019186 ENSG00000186104 PMC3574275__F1 Structural and functional characteristics of the human CD38 molecule ENSG00000177455 ENSG00000186716 ENSG00000110651 ENSG00000121966 PMC5888214__F4 The SREBP pathway regulates cellular cholesterol metabolism ENSG00000130164 ENSG00000113161 ENSG00000186480 ENSG00000141458 PMC9155920__F2 Beneficial Effects of Chinese Herbal Monomers on Ameliorating Diabetic Cardiomyopathy via Nrf2 Signaling ENSG00000162711 ENSG00000181019 ENSG00000172936 ENSG00000079999 PMC4841706__F5 Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases ENSG00000112576 ENSG00000134057 ENSG00000135446 ENSG00000106459 PMC9155920__F3 Beneficial Effects of Chinese Herbal Monomers on Ameliorating Diabetic Cardiomyopathy via Nrf2 Signaling ENSG00000079999 PMC7189101__F10 Proposed model showing the connecting link between AKT and MASTL signaling during mitosis ENSG00000143420 ENSG00000120539 PMC6372796__F9 Proposed model of IFN and inflammasome activation by HCMV and IL-1B inhibition by IE86 ENSG00000278718 ENSG00000164430 ENSG00000115415 ENSG00000163568 ENSG00000135517 ENSG00000142166 PMC9005190__F3 Receptor-specific signaling signatures ENSG00000198670 ENSG00000127948 ENSG00000026103 PMC5879765__F4 Osteogenic differentiation through p38 MAPK signaling pathway ENSG00000099985 ENSG00000214285 PMC8621500__F7 Global Analysis of Transcriptome and Translatome Revealed That Coordinated WNT and FGF Regulate the Carapacial Ridge Development of Chinese Soft-Shell Turtle ENSG00000087095 ENSG00000100592 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000196470 PMC8627637__F1 Transcriptional activation of antioxidant gene expression by Nrf2 protects against mitochondrial dysfunction and neuronal death associated with acute and chronic neurodegeneration ENSG00000010810 ENSG00000079999 PMC6513188__F8 Schematic diagram for the inhibitory mechanism of CYC116 in mast cell activation ENSG00000213658 ENSG00000010810 ENSG00000124181 PMC8291708__F1 De novo purine synthesis (DNPS) pathway ENSG00000128050 ENSG00000198931 PMC3722362__F3 Regulation of Iron Absorption in Hemoglobinopathies ENSG00000245848 ENSG00000010704 ENSG00000106327 ENSG00000105697 ENSG00000273686 ENSG00000168610 ENSG00000130513 PMC4937730__F1 Human polyamine biosynthesis, metabolism and transport and the methionine salvage pathway ENSG00000168003 ENSG00000099810 ENSG00000123505 ENSG00000116649 ENSG00000102172 PMC5296245__F2 Restoring sAPPA functions as a potential treatment for Alzheimer’s disease ENSG00000137845 PMC3836673__F1 Intracellular effects of estrogen are exerted through two main pathways, genomic and non-genomic ENSG00000291971 ENSG00000167941 ENSG00000185591 PMC9048097__F9 Luteolin attenuates the chemoresistance of osteosarcoma through inhibiting the PTN/Beta-catenin/MDR1 signaling axis by upregulating miR-384 ENSG00000105894 ENSG00000134982 ENSG00000168036 PMC3338341__F1 Repressed (left) and activated (right) canonical HH signaling pathways ENSG00000106571 ENSG00000164690 ENSG00000171791 ENSG00000139549 ENSG00000128602 ENSG00000118971 ENSG00000163501 PMC3338341__F2 Mechanisms of activation of HH signaling in hematological cancers ENSG00000164690 ENSG00000171791 ENSG00000139549 ENSG00000128602 ENSG00000118971 ENSG00000163501 ENSG00000118777 PMC3288889__F5 Ephrin-B cleavage and signaling ENSG00000291971 ENSG00000168036 PMC4026305__F1 Nox NADPH Oxidases and the Endoplasmic Reticulum ENSG00000128272 ENSG00000144895 ENSG00000086991 ENSG00000100219 PMC9130907__F1 Hemostasis and tumor immunity ENSG00000143839 PMC3219632__F11 Suppressor of Cytokine Signalling-6 Promotes Neurite Outgrowth via JAK2/STAT5-Mediated Signalling Pathway, Involving Negative Feedback Inhibition ENSG00000170677 PMC12109684__F7 Schematic diagram illustrating the proposed mechanism by which AHE-EA-C exerts its anti-leukemic effects in AML cells ENSG00000135446 PMC6946788__F2 Decorin and biglycan participate in multiple signaling pathways of innate and adaptive immune responses ENSG00000162711 ENSG00000105329 ENSG00000125538 ENSG00000172936 PMC5489557__F7 Mechanism for PE’s effects on hepatocellular carcinoma cells ENSG00000128272 ENSG00000144895 PMC6430464__F9 Proposed model depicting the possible mechanism of XIST on mediating cell proliferation, viability and apoptosis via generating a negative feedback regulation of NF‐KB/NLRP3 inflammasome pathway ENSG00000162711 ENSG00000125538 PMC3255271__F1 Study schema ENSG00000115415 ENSG00000118777 ENSG00000168610 PMC6350112__F1 COMMD7 Regulates NFKB Signaling Pathway in Hepatocellular Carcinoma Stem-like Cells ENSG00000173163 ENSG00000149600 PMC5746469__F3 Initiation of oocyte and follicular growth ENSG00000124102 ENSG00000198793 ENSG00000108443 ENSG00000187840 PMC5994511__F2 Summary of the speculative roles of UNC5C in AD pathogenesis PMC5896264__F1 Central C metabolic network of Brucella (adapted from ) ENSG00000197713 ENSG00000122966 ENSG00000172005 PMC8207419__F5 Cytoplasmic‐translocated Ku70 senses intracellular DNA and mediates interferon‐lambda1 induction ENSG00000183735 ENSG00000125347 ENSG00000276561 PMC4106657__F4 Cancer driver genes and pathways ENSG00000005339 ENSG00000157764 ENSG00000178188 ENSG00000133124 ENSG00000171791 ENSG00000171606 PMC3031497__F7 Amplification of the 20q Chromosomal Arm Occurs Early in Tumorigenic Transformation and May Initiate Cancer ENSG00000101146 ENSG00000025772 PMC9321618__F3 Sigma-1 Receptor in Retina: Neuroprotective Effects and Potential Mechanisms ENSG00000181019 ENSG00000079999 PMC5097897__F4 Divergent modulation of normal and neoplastic stem cells by thrombospondin-1 and CD47 signaling ENSG00000026508 ENSG00000146648 PMC7396672__F6 C1EIP as an activator of ENO1 to promote chicken PGC formation via inhibition of the Notch signaling pathway ENSG00000074800 ENSG00000168610 PMC4586789__F3 Inhibitors of the Hh signaling pathway target different Hh signaling components ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC8363310__F3 Expanding TOR Complex 2 Signaling: Emerging Regulators and New Connections ENSG00000198793 ENSG00000136997 ENSG00000118515 ENSG00000026508 ENSG00000168036 ENSG00000164327 ENSG00000167965 ENSG00000150457 ENSG00000114019 ENSG00000131023 PMC4647710__F2 Canonical and noncanonical NFKB signaling pathways ENSG00000186716 ENSG00000173039 ENSG00000111321 PMC8392837__F1 46,XX DSD: Developmental, Clinical and Genetic Aspects ENSG00000203859 ENSG00000179142 ENSG00000127948 PMC4502937__F8 Schematic representation of the molecular interactions following macrophage and cancer cell activation ENSG00000182578 ENSG00000122691 ENSG00000136869 ENSG00000121807 PMC7756641__F4 Adaptogens on adaptive stress response intracellular signaling pathways (updated from authors’ drawings) ENSG00000170458 PMC11682995__F4 Selected signaling pathways regulated by AKR1B10 ENSG00000198074 PMC8157222__F1 Lessons from Comparison of Hypoxia Signaling in Plants and Mammals ENSG00000134086 ENSG00000159459 ENSG00000117152 ENSG00000107669 PMC8157222__F2 Lessons from Comparison of Hypoxia Signaling in Plants and Mammals ENSG00000105722 ENSG00000205221 ENSG00000159459 ENSG00000107669 PMC6475831__F2 Regulation of intestinal organoid formation by different growth factors ENSG00000154342 ENSG00000138798 ENSG00000168610 PMC4159398__F2 Membrane receptors and intracellular signaling pathways activated by IL-4 and/or IL-13 ENSG00000123496 ENSG00000105639 PMC8750478__F9 Adipose-Specific PPARA Knockout Mice Have Increased Lipogenesis by PASK–SREBP1 Signaling and a Polarity Shift to Inflammatory Macrophages in White Adipose Tissue ENSG00000057252 ENSG00000073060 ENSG00000160179 ENSG00000026103 PMC7655096__F2 Major signaling pathways during the process of osteoclast differentiation ENSG00000170909 ENSG00000101307 ENSG00000131196 ENSG00000135605 ENSG00000010671 PMC6400107__F5A Laser Microdissection-Based Tissue-Specific Transcriptome Analysis Reveals a Novel Regulatory Network of Genes Involved in Heat-Induced Grain Chalk in Rice Endosperm ENSG00000105722 ENSG00000178860 ENSG00000111837 PMC8039187__F7 Findings in the study PMC4995293__F5 Extracellular pH‐sensitive ion channels in the PNS ENSG00000184156 ENSG00000196689 PMC6580174__F9 Ingenuity Pathway Analysis Molecule Activity Predictor algorithm indicated that loss of nuclear matrix protein 4 (Nmp4) elevates protein folding and attenuates endoplasmic reticulum (ER) stress-induced apoptosis ENSG00000182446 ENSG00000134109 ENSG00000159461 ENSG00000186480 ENSG00000165280 ENSG00000197442 ENSG00000162191 ENSG00000171791 ENSG00000198168 ENSG00000151092 ENSG00000135506 ENSG00000162298 ENSG00000136986 ENSG00000180667 ENSG00000126803 ENSG00000177239 ENSG00000100219 ENSG00000130939 ENSG00000127022 ENSG00000187522 ENSG00000127191 ENSG00000136731 ENSG00000128272 ENSG00000058262 ENSG00000130175 ENSG00000137055 PMC9675361__F1 DNA repair pathways as a novel therapeutic strategy in esophageal cancer: A review study ENSG00000149311 ENSG00000051180 ENSG00000139618 PMC9270569__F1 Cardiovascular Disease in Duchenne Muscular Dystrophy ENSG00000156026 ENSG00000198626 PMC5546706__F4 Reconstructing the regulatory circuit of cell fate determination in yeast mating response ENSG00000039537 ENSG00000166278 ENSG00000197601 PMC8642693__F9 Gentiopicroside promotes the osteogenesis of bone mesenchymal stem cells by modulation of B‐catenin‐BMP2 signalling pathway ENSG00000170365 ENSG00000168036 PMC9687157__F2 MicroRNAs as Mediators of Adipose Thermogenesis and Potential Therapeutic Targets for Obesity ENSG00000108691 ENSG00000157500 ENSG00000159346 ENSG00000136869 ENSG00000285070 ENSG00000121807 ENSG00000132170 PMC6056002__F1 Rho GTPase Effectors and NAD Metabolism in Cancer Immune Suppression ENSG00000105835 ENSG00000163914 ENSG00000168036 ENSG00000130669 PMC5026315__F1 Glomerular basement membrane heparan sulfate in health and disease: a regulator of local complement activation ENSG00000039537 ENSG00000009724 ENSG00000113600 ENSG00000291559 ENSG00000288512 ENSG00000166278 ENSG00000182326 PMC6056002__F2 Rho GTPase Effectors and NAD Metabolism in Cancer Immune Suppression ENSG00000105835 ENSG00000163914 ENSG00000168036 ENSG00000130669 PMC9469902__F1 COVID-19 and the potential of Janus family kinase (JAK) pathway inhibition: A novel treatment strategy ENSG00000130234 ENSG00000146648 PMC9469902__F3 COVID-19 and the potential of Janus family kinase (JAK) pathway inhibition: A novel treatment strategy ENSG00000213928 ENSG00000105397 PMC9469902__F4 COVID-19 and the potential of Janus family kinase (JAK) pathway inhibition: A novel treatment strategy ENSG00000115904 ENSG00000168610 PMC3265021__F2 Signal transduction events that link ER stress to inflammation ENSG00000128272 ENSG00000127191 PMC8877887__F2 THAB Immunological Pathway as Protective Immune Response against Prion Diseases: An Insight for Prion Infection Therapy ENSG00000115415 PMC3925795__F1 Simplified schematic of macroautophagy in mammals ENSG00000198793 PMC7595669__F7 Lipid metabolic pathway analysis of the identified differential lipid species ENSG00000042832 ENSG00000173599 ENSG00000026103 PMC409892__F2 Apoptotic and antiapoptotic signaling pathways ENSG00000149311 ENSG00000002330 PMC4018400__F4 De Novo Characterization of the Spleen Transcriptome of the Large Yellow Croaker (Pseudosciaena crocea) and Analysis of the Immune Relevant Genes and Pathways Involved in the Antiviral Response ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000168040 ENSG00000175104 ENSG00000164342 PMC6754541__F3 Genome-based metabolic model for cable bacteria with emphasis on electron flow and energy conservation during oxygen and nitrate-dependent sulfide oxidation ENSG00000080166 PMC4018400__F5 De Novo Characterization of the Spleen Transcriptome of the Large Yellow Croaker (Pseudosciaena crocea) and Analysis of the Immune Relevant Genes and Pathways Involved in the Antiviral Response ENSG00000110395 ENSG00000213658 ENSG00000010810 ENSG00000135446 ENSG00000163599 ENSG00000117335 ENSG00000166278 ENSG00000113263 PMC5341015__F6 Eggshell membrane powder ameliorates intestinal inflammation by facilitating the restitution of epithelial injury and alleviating microbial dysbiosis ENSG00000262785 ENSG00000074800 ENSG00000100412 ENSG00000117118 ENSG00000118520 ENSG00000036473 ENSG00000146701 ENSG00000136872 PMC6455062__F3 All currently known proteins required for germling communication and fusion in N ENSG00000070831 PMC6176282__F9 KEGG pathway suggested that various targets in p53 signaling were tightly associated with ADQ pharmacological action ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000134438 ENSG00000002330 ENSG00000135446 ENSG00000136997 ENSG00000123374 ENSG00000112378 ENSG00000164305 PMC3361329__F2 Signaling pathways of TNFAlpha-induced hepatocyte death ENSG00000078747 ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC7072595__F3 Multiple mechanisms of SFRP1 involvement in Wnt signaling pathway ENSG00000134982 ENSG00000168036 ENSG00000104332 PMC9305838__F3 Dual Function of Par3 in Tumorigenesis ENSG00000156299 ENSG00000134982 ENSG00000198742 ENSG00000168610 ENSG00000131023 PMC4113109__F2 Hedgehog signalling at a glance ENSG00000128602 PMC9305838__F4 Dual Function of Par3 in Tumorigenesis ENSG00000156299 PMC10380707__F2 Inflammation, Dopaminergic Brain and Bilirubin ENSG00000107562 ENSG00000136869 PMC5502590__F1 Diagram of major TLR pathways ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC7193097__F4 Schematic model presents the effect of tea polyphenols (TP) in attenuating STS-induced cytotoxicity in hippocampal neurons PMC9518217__F1 Toll-like receptor (TLRs) agonists and antagonists for COVID-19 treatments ENSG00000174125 ENSG00000239732 ENSG00000115993 ENSG00000170458 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC8889079__F1 NLRP3 Inflammasome in Alzheimer’s Disease and Potential Therapeutic Targets ENSG00000278718 ENSG00000162711 ENSG00000172936 PMC7787054__F3 Signal transduction pathways regulated by RIT1 ENSG00000205517 ENSG00000111537 ENSG00000002330 ENSG00000070831 ENSG00000149269 ENSG00000138798 ENSG00000006451 ENSG00000144118 ENSG00000143622 PMC7834957__F11 lncRNAS56464.1 as a ceRNA promotes the proliferation of fibroblast-like synoviocytes in experimental arthritis via the Wnt signaling pathway and sponges miR-152-3p ENSG00000134982 ENSG00000168036 ENSG00000106483 PMC7862225__F2 Build-UPS and break-downs: metabolism impacts on proteostasis and aging ENSG00000177169 ENSG00000284774 ENSG00000144895 ENSG00000112561 ENSG00000167658 ENSG00000120860 ENSG00000100219 PMC8950196__F6 CDH1 Germline Variants in a Tunisian Cohort with Hereditary Diffuse Gastric Carcinoma ENSG00000134982 ENSG00000168036 PMC7254133__F7 Model representing the hetIL-15 triggered pathway for tumor infiltration by lymphocytes and dendritic cells ENSG00000186810 ENSG00000111537 ENSG00000140968 ENSG00000138755 ENSG00000173578 ENSG00000143184 PMC12023894__F3 Natural compounds act on breast cancer (BC) through the Hedgehog (Hh) signaling pathway ENSG00000148400 ENSG00000074181 ENSG00000125538 ENSG00000272398 ENSG00000026508 ENSG00000168036 ENSG00000164690 ENSG00000114315 ENSG00000128602 PMC6379985__F9 Schematic diagram shows the mechanism underlying cTFRC as a ceRNA for miR-107 ENSG00000198793 ENSG00000072274 ENSG00000168036 PMC12023894__F1 Transmission of the classical Hedgehog (Hh) signaling pathway ENSG00000106571 ENSG00000117425 ENSG00000166813 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC12023894__F2 Transmission of the non-classical Hedgehog (Hh) signaling pathway ENSG00000138795 ENSG00000281324 ENSG00000002330 ENSG00000157764 ENSG00000162337 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000121879 ENSG00000106571 ENSG00000134057 ENSG00000163914 ENSG00000139549 ENSG00000164690 ENSG00000128602 ENSG00000163501 ENSG00000146648 PMC5810418__F10 Two B-hyperpaths computed in the full NCI-PID signaling pathway ENSG00000134982 ENSG00000168036 PMC4863690__F1 Emerging treatment options for myelofibrosis: focus on pacritinib ENSG00000198793 PMC6484401__F1 Lining up for quality control: linear ubiquitin and proteotoxicity ENSG00000197386 ENSG00000185591 ENSG00000154124 PMC11652534__F3 Annotated map of the target genes related to Beta-sitosterol in VR on RA-related signaling pathways ENSG00000087095 ENSG00000171105 ENSG00000002330 ENSG00000198793 ENSG00000127528 ENSG00000168610 ENSG00000177455 ENSG00000145604 ENSG00000149311 ENSG00000104894 ENSG00000123374 ENSG00000145782 ENSG00000176165 PMC7937946__F2 NetworkAnalyst visualization of Reactome pathway “neutrophil degranulation” genes with elevated expression in individuals from Endotype A ENSG00000277571 ENSG00000150991 ENSG00000140575 ENSG00000196549 ENSG00000163220 ENSG00000188229 PMC8465210__F3 Oncogenic Signaling Disruptor, NDRG1: Molecular and Cellular Mechanisms of Activity PMC9157408__F2 Is there a role for HSF1 in viral infections? ENSG00000284774 ENSG00000198793 PMC11893456__F8 The main pathological changes in COVID-19 brains and related molecular pathways identified ENSG00000168329 ENSG00000118785 ENSG00000026508 ENSG00000173614 ENSG00000005381 ENSG00000064012 PMC8268933__F3 Dietary n–3 and n–6 Polyunsaturated Fatty Acids in Inflammation and Cancerogenesis ENSG00000135446 ENSG00000105810 ENSG00000121966 ENSG00000104368 PMC3248191__F7 Network Modeling of MDM2 Inhibitor-Oxaliplatin Combination Reveals Biological Synergy in wt-p53 solid tumors ENSG00000111057 ENSG00000144802 ENSG00000185215 ENSG00000163739 PMC2966944__F8 Cartoon summary of expression and anatomical data, and a model for phases of A/P axis re-organization ENSG00000168036 ENSG00000104332 ENSG00000125084 PMC6279860__F2 PD-L1/PD-1 signaling pathway and the correlated network ENSG00000291603 ENSG00000156127 ENSG00000138798 ENSG00000146648 PMC10915952__F2 Small molecule compounds inducing the osteogenic differentiation of mesenchymal stem cells ENSG00000170365 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11816792__F3 LncRNAs involved in diabetic foot ulcer healing ENSG00000147099 ENSG00000122691 ENSG00000163291 ENSG00000125533 ENSG00000136826 PMC9223893__F1 Gene Expression of the D-Series Resolvin Pathway Predicts Activation of Anti-Tumor Immunity and Clinical Outcomes in Head and Neck Cancer ENSG00000171049 ENSG00000106853 ENSG00000125245 PMC2716493__F1 Two main pathways involved in apoptosis regulation ENSG00000002330 ENSG00000026103 PMC10915952__F3 The crosstalk between the Wnt and bone morphogenetic protein signaling pathways in osteogenesis ENSG00000178860 ENSG00000170365 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC8938628__SF1 Design, synthesis and evaluation of 4,7-disubstituted 8-methoxyquinazoline derivatives as potential cytotoxic agents targeting Beta-catenin/TCF4 signaling pathway ENSG00000281879 PMC6279860__F1 Targeted therapy for recurrent/metastatic head and neck cancers ENSG00000134982 ENSG00000291971 ENSG00000138798 ENSG00000163599 ENSG00000198793 ENSG00000112715 ENSG00000127191 ENSG00000168610 ENSG00000163235 ENSG00000082512 ENSG00000056558 ENSG00000131323 ENSG00000146648 ENSG00000150630 PMC11816792__F2 Wounds healing by exosomes derived from adipose stem cells containing lncRNA ENSG00000177169 ENSG00000162733 ENSG00000125398 ENSG00000122691 ENSG00000163291 ENSG00000112715 ENSG00000166147 ENSG00000168610 PMC11669685__F6 Schematic summary of the effect and mechanism of baicalin on H2O2-induced oxidative stress, inflammation and apoptosis in BMECs ENSG00000181019 ENSG00000079999 PMC12155367__F8 HH signaling pathway functions in the E ENSG00000165115 ENSG00000132646 ENSG00000168036 ENSG00000123374 ENSG00000128602 PMC3193228__F5 Possible mechanisms of involvement of nuclear receptor LRH-1 in development of pancreatic cancer ENSG00000168036 PMC8452524__F1A Cytokine storm in the pathophysiology of COVID-19: Possible functional disturbances of miRNAs ENSG00000162711 ENSG00000140564 ENSG00000086991 ENSG00000168610 ENSG00000276561 ENSG00000183735 ENSG00000088888 ENSG00000130234 ENSG00000184012 ENSG00000134070 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC1847401__F4 Genes of the insulin/IGF-2 signaling pathway are required for induced stress resistance and induced life extension ENSG00000118515 PMC4677197__F1 Canonical Wnt signalling pathway implicated in diabetic nephropathy ENSG00000134982 ENSG00000168036 PMC6374915__F1 Different forms of programmed cell death and associated cascades ENSG00000132906 ENSG00000162711 ENSG00000124256 ENSG00000137275 ENSG00000137757 ENSG00000196954 ENSG00000120868 ENSG00000168040 ENSG00000168404 ENSG00000064012 ENSG00000164305 ENSG00000285379 PMC4684823__F9 Schematic summary depicting fluoride-induced oxidative damage and adaptive response ENSG00000149311 ENSG00000175567 ENSG00000096717 PMC7918312__F7 Schematic illustration showing activation of the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway and how PRKAR1B-AS2 regulates it PMC7379154__F2 Proposed model of skin-associated B cell functions in Alpha-gal sensitization from tick bites ENSG00000239732 ENSG00000111537 ENSG00000105656 ENSG00000136869 ENSG00000112486 PMC5869742__F7 Inhibitors of prostaglandin synthesis in uterine fluid of pregnant mares ENSG00000106853 ENSG00000275565 PMC9144962__F1 Extracellular Vesicles—A New Potential Player in the Immunology of Renal Cell Carcinoma ENSG00000139193 ENSG00000276051 ENSG00000168610 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC3645738__F4 Hypothetical time course of the unfolded protein response in mammals ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC5869742__F5 Involvement of proteins found in the yolk sac fluid and the uterine fluid of pregnant mares in GO terms and pathways representing embryo-maternal interaction ENSG00000291931 ENSG00000105401 ENSG00000107798 ENSG00000121058 ENSG00000115904 ENSG00000060138 ENSG00000112715 ENSG00000137845 ENSG00000092820 ENSG00000164104 ENSG00000147274 ENSG00000165795 ENSG00000136807 ENSG00000111229 ENSG00000088247 ENSG00000163017 ENSG00000037280 ENSG00000169067 ENSG00000122862 ENSG00000276838 PMC2694616__F1 Genomic Strategy to Elucidate Modules of Oncogenic Pathway Signaling Networks ENSG00000149311 ENSG00000198793 ENSG00000177606 PMC4671004__F1 BIM and mTOR expression levels predict outcome to erlotinib in EGFR-mutant non-small-cell lung cancer ENSG00000065357 ENSG00000065989 ENSG00000198793 ENSG00000164327 ENSG00000171791 ENSG00000146648 PMC2696130__F3 Liquid Movement Across the Surface Epithelium of Large Airways ENSG00000001626 PMC2696130__F4 Liquid Movement Across the Surface Epithelium of Large Airways ENSG00000001626 PMC3637405__F2 Regulation of the p53-MDM2-MDMX pathway by DUBs ENSG00000106346 PMC7552962__F1 Proposed model of interactions between ion channels and Wnt signaling ENSG00000134982 ENSG00000072315 ENSG00000001626 PMC6430251__F1 Schematic diagram to illustrate the activation of the nuclear factorKB (NFKB) pathway in the radiation-induced rescue effect (RIRE) ENSG00000173039 ENSG00000127191 ENSG00000139618 PMC5805701__F10 An atypical IL-6-Stat3-RFX1-IL-17A regulatory pathway in CD4+ T cells of SLE patients ENSG00000151376 ENSG00000288283 ENSG00000112115 ENSG00000168610 PMC7333668__F1 Myosin light-chain phosphatase (MLCP) through regulation of myosin phosphatase target subunit 1 (MYPT1) ENSG00000171759 ENSG00000168938 PMC7694028__F1A BRAF Mutation in Colorectal Cancers: From Prognostic Marker to Targetable Mutation ENSG00000157764 ENSG00000138798 ENSG00000146648 PMC7893136__F3 Effect of treatment with EPS L (A,B) or EPS P (B) on apoptotic signaling pathway ENSG00000104689 ENSG00000137275 ENSG00000125538 ENSG00000127191 ENSG00000184216 PMC5266718__F8 Schematic model of the S ENSG00000138798 ENSG00000146648 PMC8473743__F5 Utilizing Network Pharmacology to Explore the Possible Mechanism of Coptidis Rhizoma in Kawasaki Disease ENSG00000104365 ENSG00000183735 ENSG00000198793 ENSG00000173039 ENSG00000121879 ENSG00000077782 ENSG00000073756 ENSG00000164305 ENSG00000007171 PMC3738179__F1 Molecular Pathways: The Role of Primary Cilia in Cancer Progression and Therapeutics with a Focus on Hedgehog Signaling ENSG00000145321 ENSG00000128602 PMC6627039__F1 Viral appropriation of cellular nucleocytoplasmic transport ENSG00000124789 ENSG00000115415 ENSG00000110713 ENSG00000058804 ENSG00000113569 ENSG00000213024 PMC8452524__F2A Cytokine storm in the pathophysiology of COVID-19: Possible functional disturbances of miRNAs ENSG00000162711 ENSG00000183735 ENSG00000140564 ENSG00000088888 ENSG00000130234 ENSG00000166260 ENSG00000184012 ENSG00000172936 ENSG00000168610 ENSG00000276561 ENSG00000164342 PMC3837323__F1 PI3K/Akt/mTOR signaling pathway ENSG00000145604 ENSG00000166349 ENSG00000002330 ENSG00000155792 ENSG00000175097 PMC5827530__F7 Gemcitabine/birinapant effects on upstream regulatory proteins ENSG00000142627 ENSG00000128951 ENSG00000183691 ENSG00000169710 ENSG00000120885 ENSG00000186847 ENSG00000103490 ENSG00000167880 ENSG00000134057 ENSG00000143320 ENSG00000015285 ENSG00000117528 ENSG00000118898 ENSG00000140464 ENSG00000136108 ENSG00000170477 ENSG00000026103 ENSG00000177425 ENSG00000087274 PMC8010701__F2 Mevalonate pathway ENSG00000160752 ENSG00000110921 ENSG00000112972 ENSG00000116133 ENSG00000172893 ENSG00000197429 ENSG00000113161 ENSG00000104549 ENSG00000120437 ENSG00000167508 ENSG00000075239 ENSG00000062485 PMC2781822__F2 Resolution of immune activation defines nonpathogenic SIV infection ENSG00000198793 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC5432227__F6 Metabolic heterogeneity signature of primary treatment-naïve prostate cancer ENSG00000059573 ENSG00000100033 ENSG00000115419 PMC6186045__F5 Regulatory network analysis of lncRNA-miRNA-mRNA and circRNA-miRNA-mRNA ENSG00000153107 ENSG00000063978 ENSG00000165119 ENSG00000137198 ENSG00000125818 ENSG00000059378 ENSG00000156521 ENSG00000138385 PMC8010701__F3 Cholesterol homeostatic processes governing the vertebrate retina ENSG00000110921 ENSG00000197713 ENSG00000135218 ENSG00000130164 ENSG00000116133 ENSG00000036530 ENSG00000113161 ENSG00000104549 ENSG00000075239 ENSG00000135929 PMC3738179__F2 Molecular Pathways: The Role of Primary Cilia in Cancer Progression and Therapeutics with a Focus on Hedgehog Signaling ENSG00000128602 PMC5693733__F3 Melatonin and its metabolites act as radioprotectors on epidermal keratinocytes and melanocytes ENSG00000108582 ENSG00000136936 ENSG00000079999 PMC3675167__F8 Caspase-11 Activation in Response to Bacterial Secretion Systems that Access the Host Cytosol ENSG00000162711 ENSG00000125538 ENSG00000172936 ENSG00000091106 PMC4696015__F2 Androgen pathway resistance in prostate cancer and therapeutic implications ENSG00000198793 PMC6832561__F3 MRNA-miRNA interactions associated with the vascular endothelial growth factor (VEGF) signaling pathway ENSG00000132906 ENSG00000142192 ENSG00000063176 ENSG00000101474 ENSG00000002330 ENSG00000291971 ENSG00000166501 ENSG00000073756 PMC7260598__F2 ACE/Angiotensin II/AT1R and ACE2/MasR axis ENSG00000239732 ENSG00000130234 ENSG00000136869 ENSG00000049768 PMC3122959__F1 Hedgehog signaling in skin cancers ENSG00000180447 ENSG00000112210 ENSG00000144857 ENSG00000166813 ENSG00000171791 ENSG00000128602 PMC6778014__F1 SIRTUIN 3, ENDOTHELIAL METABOLIC REPROGRAMMING AND HEART FAILURE WITH PRESERVED EJECTION FRACTION ENSG00000157764 PMC4009948__F1 Cap-dependent and elongation translational control by GNRH ENSG00000198793 ENSG00000284161 ENSG00000167658 PMC8463267__AF1 Combination therapy with miR34a and doxorubicin synergistically inhibits Dox-resistant breast cancer progression via down-regulation of Snail through suppressing Notch/NFKB and RAS/RAF/MEK/ERK signaling pathway ENSG00000170558 ENSG00000026508 PMC3757375__F1 Signal Transduction Pathways controlled by the activation of epidermal growth factor receptors (EGFR) ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000146648 PMC9099445__F1 DNA Double-Strand Breaks as Pathogenic Lesions in Neurological Disorders ENSG00000143799 ENSG00000149311 ENSG00000175054 ENSG00000197299 ENSG00000051180 ENSG00000140398 PMC3206016__F9 Putting into Practice Domain-Linear Motif Interaction Predictions for Exploration of Protein Networks ENSG00000151276 PMC7833977__F9 Interferon stimulating genes (ISGs) in the pathway ENSG00000159128 ENSG00000213928 ENSG00000187608 ENSG00000148660 ENSG00000105397 ENSG00000157601 ENSG00000111331 ENSG00000276561 PMC4935448__F4 Proposed model of miRNA regulation by simvastation and possible protective role of ubiquinol ENSG00000073734 ENSG00000171791 ENSG00000109586 ENSG00000175104 ENSG00000184216 PMC3995058__F4 Mechanism of rejection of MHCIINEG myeloma cells by Id-specific CD4+ T cells ENSG00000139193 ENSG00000169245 ENSG00000091972 ENSG00000134982 ENSG00000138755 ENSG00000026508 ENSG00000126353 PMC7826519__F3 Lipid synthetic pathway ENSG00000198793 ENSG00000155792 ENSG00000169710 ENSG00000167965 PMC4836208__F3 Targeting aberrant HH-GLI pathway ENSG00000128602 PMC9312479__F1 Mitochondrial Metabolism, AMPK-SIRT Mediated Pathway, LncRNA and MicroRNA in Osteoarthritis ENSG00000162711 ENSG00000198793 ENSG00000158828 ENSG00000162924 ENSG00000265972 ENSG00000142082 ENSG00000062485 PMC4836208__F1 Key components of the mammalian HH signalling pathway ENSG00000168283 ENSG00000106571 ENSG00000164161 ENSG00000078747 ENSG00000167779 ENSG00000134853 ENSG00000121067 ENSG00000171791 ENSG00000133961 ENSG00000114315 ENSG00000128602 ENSG00000081189 PMC6942366__F8 The role of HULC in hLCSCs ENSG00000144848 ENSG00000096717 PMC8629895__F9 Sestrin2 protects against lethal sepsis by suppressing the pyroptosis of dendritic cells ENSG00000278718 ENSG00000162711 ENSG00000128272 ENSG00000144895 ENSG00000125538 ENSG00000285069 PMC7938643__F1 Interplay between the renin-angiotensin-aldosterone system (RAAS) and the bradykinin (BK) system and chymase ENSG00000130234 ENSG00000122194 PMC5431483__F1 PI3K/Akt/mTOR signaling pathway and pharmacological compounds used to modulate its activity PMC2571037__F1 Anticancer therapy: boosting the bang of Bim ENSG00000002330 ENSG00000198793 PMC9499983__F6 RNA modifications: importance in immune cell biology and related diseases ENSG00000145388 ENSG00000284774 ENSG00000037897 ENSG00000198492 ENSG00000037474 ENSG00000168610 ENSG00000136231 ENSG00000065978 ENSG00000160193 ENSG00000149658 ENSG00000174173 ENSG00000073792 ENSG00000105246 ENSG00000275272 ENSG00000089195 ENSG00000165819 ENSG00000132275 PMC6316356__F2 Graphic representation of the hepatic Hepc pathway in conditions of systemic iron increase ENSG00000010704 ENSG00000106327 ENSG00000187045 PMC3307881__F5 Inhibition of the Nedd8 system sensitizes cells to DNA Inter-strand crosslinking agents ENSG00000149311 ENSG00000175054 ENSG00000144554 ENSG00000132646 PMC11274515__F1 Signaling cascades of autophagy in hepatocellular carcinoma cells (HCCs) ENSG00000177169 ENSG00000146648 PMC11274515__F3 Various natural compounds (EGCG, emodin, quercetin and crocin) inhibit HCC through interconnected signaling pathways ENSG00000198793 PMC9237249__F2 COVID-19 Causing ARDS: Exploring the Possibility of Preventing and Treating SARS-CoV-2 ENSG00000130234 ENSG00000026103 PMC6625100__F7 Showing Possible effect of the mutation in leptin–leptin receptor signaling pathway ENSG00000172680 ENSG00000168610 PMC5685683__F6 BMAL1 facilitates trophoblast migration and invasion via SP1-DNMT1/DAB2IP pathway in recurrent spontaneous abortion ENSG00000087245 ENSG00000136848 ENSG00000100985 PMC7389686__F1 Proteins associated with LGMD and other muscle diseases such as DMD ENSG00000168538 ENSG00000144647 ENSG00000009830 ENSG00000130714 ENSG00000121350 PMC4450280__F4 Estrogen regulates TNFA NFKB signaling pathway of osteoclasts ENSG00000103035 ENSG00000185627 ENSG00000108344 ENSG00000173692 ENSG00000163636 ENSG00000141655 PMC4450280__F5 Estrogen regulates apoptosis signaling pathway of osteoclasts ENSG00000132906 ENSG00000102871 ENSG00000138794 ENSG00000196954 ENSG00000095015 ENSG00000065559 ENSG00000168040 ENSG00000127191 ENSG00000164305 ENSG00000089685 ENSG00000177606 ENSG00000056558 ENSG00000131323 ENSG00000120868 ENSG00000064012 ENSG00000026103 PMC3224136__F7 Schematic pathway showing a possible role for STC2 in affecting the PERK signalling pathway ENSG00000128272 ENSG00000144895 ENSG00000162772 PMC4450280__F6 Estrogen regulates MAPK signaling pathway of osteoclasts ENSG00000132906 ENSG00000070831 ENSG00000138794 ENSG00000115590 ENSG00000149269 ENSG00000177606 ENSG00000095015 ENSG00000065559 ENSG00000064012 ENSG00000164305 PMC4450280__F7 Estrogen regulates cell adhesion and polarization signaling pathway of osteoclasts ENSG00000259207 ENSG00000070831 ENSG00000143878 ENSG00000050748 ENSG00000150093 ENSG00000115221 ENSG00000067900 ENSG00000099942 ENSG00000107263 ENSG00000169750 ENSG00000177606 ENSG00000092841 ENSG00000139626 PMC4791205__F11 YAP Induces High-Grade Serous Carcinoma in Fallopian Tube Secretory Epithelial Cells ENSG00000066468 ENSG00000160867 ENSG00000150457 ENSG00000077782 ENSG00000131023 PMC4450280__F8 Estrogen regulates Delta-Notch signaling pathway of osteoclasts ENSG00000148400 ENSG00000173039 ENSG00000196498 ENSG00000137845 PMC4747906__F1 Epidermal growth factor receptor (EGFR) is restricted to the basal surface of the airway epithelial cells ENSG00000138798 ENSG00000146648 PMC4931665__F1 NFKB signaling consists of two main branches: canonical and non-canonical ENSG00000104856 ENSG00000107562 ENSG00000026508 ENSG00000111321 ENSG00000100985 PMC9405087__F2 Neutrophils and Neutrophil Extracellular Traps in Cardiovascular Disease: An Overview and Potential Therapeutic Approaches ENSG00000110799 ENSG00000189403 PMC5763573__F6 TGF-Beta-induced fibrosis signaling pathway ENSG00000087245 ENSG00000100985 PMC6789908__F1 Rationale and workflow of CRISPR-BEST ENSG00000145321 ENSG00000174611 ENSG00000204941 PMC5054600__F7 Working model of lifespan extension induced by impt-1 knockdown in C ENSG00000089154 ENSG00000169136 ENSG00000154059 PMC10944225__F8 Schematic summary of the mechanism of the role of BMP2 and the BMPR/Smad1 signaling pathway in the modulation of CGRP expression and progression of BCP ENSG00000170365 ENSG00000110680 PMC2864407__F1 Description of the sex hormone metabolic pathway: genes involved in synthesis, bioactivation, metabolism, and inactivation of estrogen and other hormones ENSG00000082175 ENSG00000129214 PMC11817786__F5 Integrative multi-omics data analysis, including DEGs, DEPs, and DElncRNAs ENSG00000075223 ENSG00000068976 ENSG00000067606 PMC19384__F10 A model of thymic differentiation ENSG00000158825 ENSG00000168685 PMC2631307__F1 Glucocorticoids and neonatal brain injury: the hedgehog connection ENSG00000164690 ENSG00000128602 PMC4556222__F2 Androgen synthesis pathway ENSG00000086696 ENSG00000151632 ENSG00000196620 ENSG00000203857 ENSG00000187134 PMC5902856__F4 Comparison of phospholipid (PL) synthesis and lipoprotein (LP) formation pathways between 0.16, 2.5 and 10 g salmon ENSG00000135218 ENSG00000111666 ENSG00000184207 ENSG00000241878 ENSG00000188783 ENSG00000133027 PMC9545829__F7 miR‐378a regulates keratinocyte responsiveness to interleukin‐17A in psoriasis ENSG00000172216 ENSG00000100906 ENSG00000115009 ENSG00000163702 PMC7479481__F2 Major signalling pathways of DNA sensors ENSG00000164430 ENSG00000163568 ENSG00000163565 ENSG00000174953 ENSG00000172936 ENSG00000107201 ENSG00000276561 PMC6600158__F2 Ubiquitination-monitored regulation of the Wnt/Beta-Catenin pathway in colorectal cancer (CRC) cells ENSG00000175931 ENSG00000134982 ENSG00000168036 ENSG00000196470 ENSG00000108106 PMC8504117__F2 Advances in the study of emodin: an update on pharmacological properties and mechanistic basis ENSG00000057935 ENSG00000136535 ENSG00000148400 ENSG00000096717 ENSG00000114315 PMC4890888__F2 EGFR signalling pathway ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC6006192__F1 The intramitochondrial iron–sulfur cluster biosynthesis pathway (see text for details) ENSG00000121897 ENSG00000165898 ENSG00000155287 ENSG00000161513 ENSG00000136003 ENSG00000169599 ENSG00000135070 PMC3913761__F2 Emerging roles of store-operated Ca2+ entry through STIM and ORAI proteins in immunity, hemostasis and cancer ENSG00000175938 ENSG00000167323 ENSG00000293604 ENSG00000138798 PMC11307123__F6 Mechanism of diabetes promoting myocardial fibrosis via AMP-activated protein kinase (AMPK)/enhancer of zeste homolog 2 (EZH2)/peroxisome proliferator-activated receptor G (PPARG) signaling pathway ENSG00000074266 ENSG00000178691 PMC10137169__F1 One Carbon Metabolism and S-Adenosylmethionine in Non-Alcoholic Fatty Liver Disease Pathogenesis and Subtypes ENSG00000173599 ENSG00000116761 ENSG00000116984 ENSG00000133027 PMC6678221__F1 Role of the canonical Wnt/Beta-catenin pathway in cancer metabolism ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000099194 PMC6004076__F3 Mitotic errors can trigger activation of p53 ENSG00000149311 ENSG00000150457 PMC9600220__F2 Dual Immune Regulatory Roles of Interleukin-33 in Pathological Conditions ENSG00000127445 ENSG00000137033 ENSG00000198793 ENSG00000107485 ENSG00000172936 ENSG00000185187 ENSG00000175104 ENSG00000168610 ENSG00000184216 PMC6167061__F2 (A, B) Intracellular pharmacological chaperoning and matchmaking of G protein-coupled receptors (GPCRs) and downstream effects ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC2696319__F1 Sites of mutation which can result in activation of the Raf>MEK>ERK pathway ENSG00000157404 ENSG00000291971 PMC4720504__F1 Apoptosis pathway: (A) The different paths that a cell can take during the activation of cell death ENSG00000120868 ENSG00000168040 PMC9913267__F3 Synthesis and Significance of Arachidonic Acid, a Substrate for Cyclooxygenases, Lipoxygenases, and Cytochrome P450 Pathways in the Tumorigenesis of Glioblastoma Multiforme, Including a Pan-Cancer Comparative Analysis ENSG00000096088 ENSG00000106853 PMC9913267__F4 Synthesis and Significance of Arachidonic Acid, a Substrate for Cyclooxygenases, Lipoxygenases, and Cytochrome P450 Pathways in the Tumorigenesis of Glioblastoma Multiforme, Including a Pan-Cancer Comparative Analysis ENSG00000167261 ENSG00000283887 PMC6813721__F7 Inferred role of ACSL1 in sepsis ENSG00000151726 ENSG00000111537 PMC11959162__F2 Phosphorylation in signaling pathways involved in osteoblast differentiation ENSG00000170365 ENSG00000281324 ENSG00000125398 ENSG00000162337 ENSG00000120693 ENSG00000168036 ENSG00000128602 PMC10876676__F2 Upon infection with HIV, the virus infiltrates cluster differentiation positive (CD4+) T-lymphocytes and induce pro-inflammatory intracellular micro-environment marked by increased ILB ENSG00000162692 ENSG00000005381 ENSG00000132693 PMC11959162__F3 Ubiquitination in bone homeostasis and osteoporosis ENSG00000145604 ENSG00000066468 ENSG00000170365 ENSG00000069869 ENSG00000281324 ENSG00000162337 ENSG00000198742 ENSG00000168036 ENSG00000134588 ENSG00000103264 PMC3509680__F3 Functional roles of the arenavirus Z protein in the viral life cycle ENSG00000140464 PMC4226683__F6A Transcriptomic profile induced in bone marrow mesenchymal stromal cells after interaction with multiple myeloma cells: implications in myeloma progression and myeloma bone disease ENSG00000110944 ENSG00000163464 ENSG00000108691 ENSG00000081041 ENSG00000149968 ENSG00000163739 ENSG00000163734 ENSG00000124875 ENSG00000166670 ENSG00000100985 ENSG00000115009 PMC3701121__F3 Angiogenesis signaling pathways in epilepsy ENSG00000132906 ENSG00000291971 ENSG00000163914 ENSG00000112715 PMC7330666__F2 EGFL6 regulates angiogenesis by activating Akt/ERK signaling ENSG00000198759 ENSG00000198793 PMC9587056__F9 Hypothesis-driven dragging of transcriptomic data to analyze proven targeted pathways in Rhinella arenarum larvae exposed to organophosphorus pesticides ENSG00000211445 ENSG00000110711 ENSG00000088826 ENSG00000148832 ENSG00000104904 ENSG00000164294 ENSG00000106546 PMC7330666__F3 EGFL6 promotes tumor development by activating Wnt/Beta-catenin and Akt/ERK signaling pathways ENSG00000138795 ENSG00000134982 ENSG00000198759 ENSG00000198793 ENSG00000168036 PMC4570097__F1 T-MPs function as novel cell-free cancer vaccines ENSG00000164430 PMC9066134__F1 Coinfection of fungi with SARS-CoV-2 is a detrimental health risk for COVID-19 patients ENSG00000134982 ENSG00000130234 PMC3736525__F3 Lycopene induces cell-cycle arrest and apoptosis ENSG00000145604 ENSG00000002330 ENSG00000135446 ENSG00000169047 ENSG00000105810 ENSG00000089289 ENSG00000140443 PMC3736525__F4 Lycopene inhibits theWnt/Beta-catenin pathway ENSG00000134982 ENSG00000168036 ENSG00000185591 ENSG00000089289 ENSG00000140443 PMC11882405__F9 Reversal of chemotherapy resistance in gastric cancer with traditional Chinese medicine as sensitizer: potential mechanism of action ENSG00000149311 ENSG00000175054 ENSG00000151012 ENSG00000135446 ENSG00000167468 PMC4278306__F2 SOX15 and other SOX family members are important mediators of tumorigenesis in multiple cancer types ENSG00000182968 ENSG00000164736 ENSG00000106571 ENSG00000124766 ENSG00000168036 ENSG00000164690 ENSG00000114315 ENSG00000074219 PMC7996097__F8 Mechanism of how taurine relieves S ENSG00000177169 ENSG00000198793 ENSG00000136869 PMC8721187__F3 Insights into the role of paraoxonase 2 in human pathophysiology ENSG00000105854 ENSG00000144895 PMC7673844__F1 Sources of serine ENSG00000284320 ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC9463538__F12 MAP3K4 promotes fetal and placental growth by controlling the receptor tyrosine kinases IGF1R/IR and Akt signaling pathway ENSG00000094631 PMC4183925__F2 Metabolic pathway of insulin signalling pathway for unigenes by KEGG annotation ENSG00000171105 ENSG00000002330 ENSG00000005882 ENSG00000198793 ENSG00000026103 PMC4939337__F3 Circadian Rhythm Signaling pathway ENSG00000146469 ENSG00000132326 ENSG00000132639 PMC2964117__F2 Small-molecule inhibition of the parasite nicotinate mononucleotide adenylyltransferase (NMNAT) ENSG00000108582 ENSG00000008130 PMC4122293__F8 Fibronectin Stimulates Endothelin-1 Synthesis in Rat Hepatic Myofibroblasts via a Src/ERK Regulated Signaling Pathway ENSG00000291971 PMC6662310__F1 Schematic of TriPOINT ENSG00000170365 ENSG00000185386 ENSG00000120693 ENSG00000154059 ENSG00000188130 ENSG00000169032 ENSG00000121879 ENSG00000171608 ENSG00000213853 ENSG00000140443 PMC12026460__F3 Comprehensive mechanism by which Irisin influences fibrosis Via Sirtuin 1 (Sirt1), peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1A)/nuclear respiratory factor 1 (NRF-1), and related pathways ENSG00000158828 ENSG00000096717 ENSG00000106459 PMC11314475__F5 Investigating the Molecular Mechanisms of Resveratrol in Treating Cardiometabolic Multimorbidity: A Network Pharmacology and Bioinformatics Approach with Molecular Docking Validation ENSG00000197043 ENSG00000105835 ENSG00000123240 ENSG00000131482 ENSG00000075142 ENSG00000138792 ENSG00000175003 ENSG00000137857 ENSG00000118526 ENSG00000187049 ENSG00000140279 ENSG00000112499 ENSG00000171202 ENSG00000117114 ENSG00000169047 ENSG00000126088 ENSG00000160161 ENSG00000163918 ENSG00000125871 ENSG00000111271 ENSG00000137656 ENSG00000187266 ENSG00000131096 ENSG00000158445 ENSG00000178726 ENSG00000164430 ENSG00000082175 ENSG00000291814 ENSG00000104320 ENSG00000163914 ENSG00000147955 ENSG00000169174 ENSG00000197635 ENSG00000109321 ENSG00000173083 ENSG00000164120 ENSG00000173402 ENSG00000132693 ENSG00000106459 ENSG00000138378 ENSG00000274247 ENSG00000160224 ENSG00000102245 ENSG00000163794 ENSG00000132646 ENSG00000143126 ENSG00000140285 ENSG00000102119 ENSG00000080618 ENSG00000115808 ENSG00000167646 ENSG00000120833 ENSG00000167720 ENSG00000095015 ENSG00000196591 ENSG00000196468 ENSG00000197442 ENSG00000166484 ENSG00000135341 ENSG00000122194 ENSG00000106683 ENSG00000131238 ENSG00000133116 ENSG00000119655 ENSG00000111341 ENSG00000076662 ENSG00000034693 ENSG00000198947 ENSG00000167434 ENSG00000182718 ENSG00000118972 ENSG00000161544 ENSG00000003436 ENSG00000111262 ENSG00000086991 ENSG00000000971 ENSG00000141052 ENSG00000171824 ENSG00000273686 ENSG00000102003 ENSG00000176153 ENSG00000163217 ENSG00000185386 ENSG00000116761 ENSG00000138092 ENSG00000150630 ENSG00000228716 ENSG00000188641 ENSG00000070193 ENSG00000090534 ENSG00000042832 ENSG00000110799 ENSG00000123454 ENSG00000124491 ENSG00000143839 ENSG00000169710 ENSG00000120885 ENSG00000163737 ENSG00000171388 ENSG00000274619 ENSG00000171720 ENSG00000073060 ENSG00000084676 ENSG00000126247 ENSG00000285395 ENSG00000204520 ENSG00000077782 ENSG00000162896 ENSG00000138449 ENSG00000122180 ENSG00000112964 ENSG00000137310 ENSG00000131095 ENSG00000257335 ENSG00000231179 ENSG00000125347 ENSG00000143387 ENSG00000004948 ENSG00000172915 ENSG00000136160 ENSG00000198125 ENSG00000146648 ENSG00000019991 ENSG00000119888 ENSG00000172893 ENSG00000105550 ENSG00000141458 ENSG00000250722 ENSG00000138185 ENSG00000123104 ENSG00000148344 ENSG00000116830 ENSG00000106546 ENSG00000163631 ENSG00000072571 ENSG00000102081 ENSG00000188157 ENSG00000104918 ENSG00000074771 ENSG00000196839 ENSG00000134363 ENSG00000198626 ENSG00000168610 ENSG00000211445 ENSG00000111537 ENSG00000156110 ENSG00000163131 ENSG00000164362 ENSG00000048052 ENSG00000005381 ENSG00000114279 PMC3892938__F2 A schematic representation of IL-12 family cytokines and the corresponding receptors and JAK-STAT signaling pathways ENSG00000162594 ENSG00000096996 ENSG00000138378 ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000105246 ENSG00000168610 PMC6338918__F1A Toxicogenomic Approach Reveals a Novel Gene Regulatory Network Active in In Vitro and In Vivo Models of Thyroid Carcinogenesis ENSG00000169962 ENSG00000134996 ENSG00000142192 ENSG00000230989 ENSG00000174145 ENSG00000137449 ENSG00000127124 ENSG00000038532 ENSG00000155115 ENSG00000168779 ENSG00000126464 ENSG00000284017 PMC3798724__F2 Wnt signaling pathway in the primary cilia ENSG00000134982 ENSG00000104290 ENSG00000168036 PMC3798724__F3 Hedgehog signaling pathway in the primary cilia ENSG00000121067 ENSG00000128602 PMC2793049__F2 Leptin signaling and leptin resistance ENSG00000178188 ENSG00000291971 ENSG00000198793 ENSG00000168610 PMC5341618__F1 Mitophagy and Alzheimer’s disease: cellular and molecular mechanisms ENSG00000110497 ENSG00000152348 ENSG00000123240 ENSG00000101460 ENSG00000099968 ENSG00000083290 ENSG00000158828 ENSG00000069509 ENSG00000057663 ENSG00000135093 ENSG00000090432 ENSG00000197769 ENSG00000183735 ENSG00000188554 ENSG00000116688 ENSG00000145782 ENSG00000171109 ENSG00000214253 PMC11353125__F1 Receptor tyrosine kinases (RTKs), epidermal growth factor receptor (EGFR), and its variant EGFRvIII activate the PI3K/AKT signaling pathway, subsequently influencing mTOR activity ENSG00000177169 ENSG00000005882 ENSG00000164327 ENSG00000146648 PMC10484649__F4 Mitogen-activated protein kinase (MAPK) signal pathway in subchondral bone ENSG00000128272 PMC2993798__F6 A conserved insulin signaling pathway in C ENSG00000171105 ENSG00000118515 PMC8576031__F3 Therapeutic vulnerabilities and regulation of SLFN11-mediated cell death ENSG00000175054 ENSG00000172716 ENSG00000111537 ENSG00000108799 PMC6461634__F5 Proposed de novo synthetic pathway of monorhamnolipids in Pseudomonas guguanensis PMC3610926__F2 Transcriptional Responses of In Vivo Praziquantel Exposure in Schistosomes Identifies a Functional Role for Calcium Signalling Pathway Member CamKII ENSG00000182533 ENSG00000156026 ENSG00000186716 PMC3323126__F3 Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus ENSG00000026508 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC9549209__F7 Carotenoids in orange carrots mitigate non-alcoholic fatty liver disease progression ENSG00000157184 ENSG00000135218 ENSG00000042832 ENSG00000161533 PMC3317170__F3 Proposed models for the activation of intracellular TLR9 and TLR3 by Leishmania ENSG00000169245 ENSG00000239732 ENSG00000111537 ENSG00000164342 PMC3317170__F1 The activation of TLR2 by Leishmania sp., leading to a proinflammatory (left), or anti-inflammatory arm (centre and right) ENSG00000172936 ENSG00000136869 PMC6087481__F1 Type I IFN-dependent pathway and ER stress response-induced pathway of IFNAR1 degradation ENSG00000105397 ENSG00000142166 PMC3160333__F2 One Carbon Metabolism in SAR11 Pelagic Marine Bacteria PMC11882405__F6 Reversal of chemotherapy resistance in gastric cancer with traditional Chinese medicine as sensitizer: potential mechanism of action ENSG00000159399 PMC7237219__F7 The role of FGF signaling pathway in blood cell migration ENSG00000137573 ENSG00000112742 PMC6087481__F2 Influenza HA-induced degradation of IFNAR1 blocks the IFNAR signaling pathway ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC11882405__F7 Reversal of chemotherapy resistance in gastric cancer with traditional Chinese medicine as sensitizer: potential mechanism of action ENSG00000104856 ENSG00000183735 ENSG00000082512 ENSG00000173039 ENSG00000172936 ENSG00000111321 ENSG00000131323 ENSG00000127191 PMC11882405__F8 Reversal of chemotherapy resistance in gastric cancer with traditional Chinese medicine as sensitizer: potential mechanism of action ENSG00000002330 ENSG00000141068 ENSG00000026103 PMC9200072__F4 Mutual Shaping of Circadian Body-Wide Synchronization by the Suprachiasmatic Nucleus and Circulating Steroids PMC7826839__F1 Role of the adenosinergic pathway in the Glioblastoma microenvironment ENSG00000142192 ENSG00000089692 ENSG00000198053 ENSG00000133937 ENSG00000196839 ENSG00000163599 ENSG00000102970 ENSG00000168036 ENSG00000049768 ENSG00000146648 ENSG00000106546 PMC5223135__F4 Proposed mechanisms of kefir peptides-mediated modulation of the lipid metabolism pathway in 30% fructose-induced NAFLD mice ENSG00000042832 ENSG00000168610 PMC5983871__F11 Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3CD protein ENSG00000107862 ENSG00000143393 ENSG00000143761 ENSG00000182827 ENSG00000173599 ENSG00000115271 ENSG00000129744 PMC7785019__F4 Groundwater Elusimicrobia are metabolically diverse compared to gut microbiome Elusimicrobia and some have a novel nitrogenase paralog ENSG00000197429 ENSG00000105402 PMC7167271__F9 PPI plot of IR and fatty acid oxidation ENSG00000107537 ENSG00000198793 PMC5485763__F2 Therapeutic Wound Healing Targets of miR-21Schematic diagram of miR-21 targets TIMP3 and PTEN ENSG00000100234 ENSG00000002330 ENSG00000198793 ENSG00000128052 PMC8618084__F2 Syngas Fermentation for the Production of Bio-Based Polymers: A Review ENSG00000116984 PMC6696068__F1 Canonical Wnt/Beta-catenin signaling pathway ENSG00000089685 ENSG00000134982 ENSG00000173273 PMC3827157__F4 Transcriptome Analysis of PPARG Target Genes Reveals the Involvement of Lysyl Oxidase in Human Placental Cytotrophoblast Invasion ENSG00000151726 ENSG00000163947 ENSG00000167772 ENSG00000197635 ENSG00000186480 ENSG00000116717 ENSG00000118777 ENSG00000140443 ENSG00000132170 PMC8391952__F1 Erythropoietin (EPO) as a Key Regulator of Erythropoiesis, Bone Remodeling and Endothelial Transdifferentiation of Multipotent Mesenchymal Stem Cells (MSCs): Implications in Regenerative Medicine PMC6613612__F7 Differentially expressed genes in p53 signaling pathway ENSG00000184990 ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000136997 ENSG00000042286 ENSG00000112378 ENSG00000196470 ENSG00000164305 ENSG00000026103 PMC3946160__F4 Glutamate, BDNF, insulin and glucagon-like peptide 1 (GLP-1) improve neuronal bioenergetics and protect the neurons against neurodegenerative disease and traumatic injury ENSG00000198793 PMC9355329__F3 Copy Number Variation of Circulating Tumor DNA (ctDNA) Detected Using NIPT in Neoadjuvant Chemotherapy-Treated Ovarian Cancer Patients ENSG00000149311 ENSG00000133433 ENSG00000284774 ENSG00000143878 ENSG00000171540 ENSG00000185164 ENSG00000285272 PMC3861317__F3 Mechanistic Phenotypes: An Aggregative Phenotyping Strategy to Identify Disease Mechanisms Using GWAS Data ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000144554 ENSG00000188827 ENSG00000187741 ENSG00000139618 PMC5669809__F3 Mixed Chimerism-Based Transplant Tolerance ENSG00000134982 ENSG00000198793 ENSG00000105639 PMC3688869__F5 Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer ENSG00000132906 ENSG00000002330 ENSG00000134982 ENSG00000095002 ENSG00000164305 PMC4816162__F1 Mitochondria-mediated intrinsic (a) and death receptor-mediated extrinsic (b) pathway ENSG00000102871 ENSG00000168040 PMC5587377__F2 Tissue Elasticity Bridges Cancer Stem Cells to the Tumor Microenvironment Through microRNAs: Implications for a “Watch-and-Wait” Approach to Cancer ENSG00000169291 ENSG00000002330 PMC8064518__F1 Canonical PI3K-mTOR and GATOR1 signaling pathway and mTORC1-independent pathways ENSG00000100150 ENSG00000114388 ENSG00000198793 ENSG00000176165 PMC8934394__F1 Interaction Between Non-Coding RNAs and Calcium Binding Proteins ENSG00000162711 ENSG00000198793 ENSG00000135932 PMC7483747__F3 IPA TGFB signaling canonical pathway analysis overlaying the WT specific gene list: genes significantly differentially expressed (adjusted p < 0.05) with a |FC|> 2.0 uniquely in WT, E16.5 versus E14.5 ENSG00000157764 ENSG00000133937 ENSG00000115297 ENSG00000156574 ENSG00000171759 PMC9467392__F7 High expression of CCNB1 driven by ncRNAs is associated with a poor prognosis and tumor immune infiltration in breast cancer ENSG00000065833 ENSG00000179091 ENSG00000132646 ENSG00000172005 ENSG00000166482 ENSG00000198363 PMC6326983__F1 Interaction between reprogramming to pluripotency and tumorigenesis ENSG00000100811 ENSG00000168283 ENSG00000140044 ENSG00000136826 PMC4098942__F3 Cancer model pathway ENSG00000171956 ENSG00000114346 ENSG00000138798 ENSG00000141068 ENSG00000120075 ENSG00000146648 ENSG00000148943 ENSG00000179295 PMC3725543__F6 FAK-mediated growth of C2C12 cells in response to IGF-I ENSG00000198793 PMC3529810__F7 Central role for endothelial human deneddylase-1/SENP8 in fine-tuning the vascular inflammatory response ENSG00000111537 ENSG00000285246 ENSG00000136869 PMC3706856__F2 The Effect of Curcumin on Breast Cancer Cells ENSG00000132646 ENSG00000168036 PMC3676658__F1 Schematic diagram showing the main components of the TGFB signaling pathway PMC5817364__F2 Polyphenols for the treatment of NAFLD ENSG00000135218 ENSG00000169047 ENSG00000079999 PMC4794511__F3 miRNAs and TGFB signaling pathway ENSG00000115461 PMC2789270__F1 TGFB: A New Role for an Old AktTOR ENSG00000087245 ENSG00000198793 ENSG00000100985 PMC3649343__F1 The cholinergic anti-inflammatory pathway depicted ENSG00000134982 PMC7294406__F4 Gene product interaction network of “InterferonG” gene set—an up-regulated pathway in subcutaneous fat of OSA subjects relative to those without OSA ENSG00000111537 ENSG00000115415 ENSG00000168610 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC7294406__F6 Cholesterol biosynthesis—a pathway that was up-regulated in OSA subjects treated with CPAP ENSG00000160752 ENSG00000110921 ENSG00000132196 ENSG00000001630 ENSG00000172893 ENSG00000149809 ENSG00000113161 ENSG00000104549 ENSG00000120437 ENSG00000167508 ENSG00000052802 PMC5590639__F9 Possible interactions between PVN inflammation and sympathoexcitation in spontaneously hypertensive rats ENSG00000125538 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000121966 ENSG00000140443 PMC11451039__F2 Modulating mechanisms of the Ang/Tie signaling pathway ENSG00000002330 ENSG00000291971 ENSG00000150907 ENSG00000162692 PMC3131208__F4 NFKB signaling pathways ENSG00000104856 ENSG00000186716 ENSG00000173039 ENSG00000111321 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC3131208__F2 Cellular targets of the Tax viral oncoprotein ENSG00000099901 ENSG00000135446 ENSG00000105810 PMC7260445__F2 Molecular mechanisms that activate membrane damage ENSG00000278718 ENSG00000039537 ENSG00000137275 ENSG00000102871 ENSG00000125538 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC8868465__F2 Uncoupling Proteins: A Systematic Review on the Mechanism Used in the Prevention of Oxidative Stress ENSG00000175567 PMC8901995__F5 Evaluation of Public–Private Partnership in the Veterinary Domain Using Impact Pathway Methodology: In-depth Case Study in the Poultry Sector in Ethiopia ENSG00000154059 ENSG00000138119 PMC9428719__F7 Metabolic management of microenvironment acidity in glioblastoma ENSG00000125166 ENSG00000047936 ENSG00000083720 PMC7352995__F2 Role of fibroblasts in mammary gland branching and BC growth ENSG00000164056 ENSG00000134853 ENSG00000146648 PMC5785559__F8 Diagram of direct and alternative Runx2-Ihh regulation in chondrogenesis ENSG00000020633 ENSG00000163501 PMC7835514__F1 Mouse lung development and early pseudoglandular branching morphogenesis ENSG00000070193 ENSG00000125398 ENSG00000164161 ENSG00000244405 ENSG00000175832 ENSG00000168036 ENSG00000136352 ENSG00000164690 PMC5530473__F1 Considering the spectrum of colorectal cancer (CRC)—conventional adenomas progress by the sequential accumulation of genetic mutations and chromosomal instability causing microsatellite stable (MSS) tumours ENSG00000157764 ENSG00000134982 ENSG00000170430 ENSG00000168036 ENSG00000078098 ENSG00000095002 ENSG00000064933 ENSG00000122512 PMC5929452__F3 Non-invasive tumor genotyping using radiogenomic biomarkers, a systematic review and oncology-wide pathway analysis ENSG00000157404 ENSG00000167083 ENSG00000148926 ENSG00000141564 ENSG00000171791 ENSG00000187266 ENSG00000100485 ENSG00000178726 ENSG00000175707 ENSG00000145431 ENSG00000041982 ENSG00000121068 ENSG00000082175 ENSG00000150907 ENSG00000136997 ENSG00000139687 ENSG00000282899 ENSG00000196712 ENSG00000114450 ENSG00000133056 ENSG00000189056 ENSG00000108342 ENSG00000163453 ENSG00000213341 ENSG00000091879 ENSG00000171303 ENSG00000136603 ENSG00000170962 ENSG00000163235 ENSG00000140285 ENSG00000080823 ENSG00000136160 ENSG00000146648 ENSG00000127948 ENSG00000168685 ENSG00000157554 ENSG00000002330 ENSG00000001167 ENSG00000138798 ENSG00000117139 ENSG00000020633 ENSG00000168036 ENSG00000112715 ENSG00000121879 ENSG00000064300 ENSG00000157557 ENSG00000136457 ENSG00000105664 ENSG00000112242 ENSG00000145623 ENSG00000115457 ENSG00000129946 ENSG00000111341 ENSG00000170430 ENSG00000185591 ENSG00000037280 ENSG00000162188 ENSG00000137673 ENSG00000101057 ENSG00000173039 ENSG00000234829 ENSG00000168610 ENSG00000147145 ENSG00000166135 ENSG00000139352 ENSG00000071564 ENSG00000096996 ENSG00000284816 ENSG00000128272 ENSG00000134853 ENSG00000131196 PMC11702196__F7 Lipid Metabolism Regulatory Network Revealed by Multi-Omics Data Analysis ENSG00000185634 ENSG00000081041 ENSG00000198408 ENSG00000170606 ENSG00000213341 ENSG00000137841 ENSG00000052802 ENSG00000179295 ENSG00000111012 ENSG00000198380 ENSG00000170458 ENSG00000163558 ENSG00000120868 ENSG00000159399 ENSG00000026103 PMC11702196__F8 Pearson Correlation Network of Lipid Metabolism-Related Molecules in Bovine Hepatic Cells Following TMAO Treatment PMC8637577__F2 Sphingolipid metabolism in the development and progression of cancer: one cancer's help is another's hindrance ENSG00000100422 ENSG00000183018 ENSG00000102172 PMC6538961__F7 A Model for cFLIPs-Dependent Lethal Ileitis(A) The complex IIb spontaneously forms in IECs overexpressing cFLIPs ENSG00000137275 ENSG00000140279 ENSG00000125538 ENSG00000168404 ENSG00000285379 ENSG00000115009 PMC8534198__F4 Methylosystem for Cancer Sieging Strategy ENSG00000145388 ENSG00000198492 ENSG00000091542 ENSG00000146457 ENSG00000165819 PMC7725436__F3 Venn diagram of differentially expressed genes ENSG00000105329 ENSG00000100906 ENSG00000177606 ENSG00000136997 ENSG00000185591 ENSG00000168610 ENSG00000136826 PMC1508148__F1 Pathway diagram of genes tested for association ENSG00000111012 ENSG00000096996 ENSG00000118785 ENSG00000019186 ENSG00000145321 ENSG00000113302 ENSG00000186104 PMC3265661__F1 Putative role of the mTOR pathway in pathogenesis and epileptogenesis of focal cortical malformations ENSG00000266173 ENSG00000198793 PMC7979776__F7 Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCA and TSC2-mTOR downregulation ENSG00000122367 ENSG00000103266 ENSG00000173599 ENSG00000152137 ENSG00000151929 PMC5407490__F1 AhR signaling inhibits crosstalk with ERA in breast cancer cells and AhR agonists and antagonists are tumor-specific anticancer agents (24, 25) ENSG00000106546 PMC9496174__F1 Gut Microbiota Regulation of AHR Signaling in Liver Disease ENSG00000110711 ENSG00000291971 ENSG00000106546 PMC5710702__F1 Three interconnected intracellular signaling pathways in pancreatic B cells ENSG00000159224 ENSG00000146469 PMC11042538__F2 Cellular senescence in cancer: molecular mechanisms and therapeutic targets ENSG00000149311 ENSG00000175054 ENSG00000151376 ENSG00000100084 ENSG00000164430 ENSG00000172216 ENSG00000111875 ENSG00000285109 ENSG00000198793 ENSG00000168610 PMC5783597__F7 Schematic diagram of the CCL2/CCR2 axis activating Hh signaling ENSG00000108691 ENSG00000164690 ENSG00000121807 ENSG00000128602 PMC6684366__F2 Biosynthetic pathway of VLC-PUFAs in the mammalian retina ENSG00000118402 ENSG00000119915 ENSG00000066322 ENSG00000197977 PMC8702962__F1 Osteosarcoma and Metastasis ENSG00000178860 ENSG00000169710 ENSG00000125968 PMC6637205__F2 Multiple signaling pathways in Sertoli cells: recent findings in spermatogenesis ENSG00000170365 ENSG00000105550 ENSG00000185591 PMC6637205__F3 Multiple signaling pathways in Sertoli cells: recent findings in spermatogenesis ENSG00000145604 ENSG00000198793 ENSG00000155792 PMC8702962__F4 Osteosarcoma and Metastasis ENSG00000179242 ENSG00000113140 ENSG00000077782 ENSG00000121966 PMC6637205__F4 Multiple signaling pathways in Sertoli cells: recent findings in spermatogenesis ENSG00000070831 ENSG00000163914 ENSG00000198087 PMC8568515__F1 MANF: A Novel Endoplasmic Reticulum Stress Response Protein—The Role in Neurological and Metabolic Disorders ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8428093__F3 Cross talk between gastric cancer stem cells and the immune microenvironment: a tumor-promoting factor ENSG00000178860 ENSG00000163739 ENSG00000026508 ENSG00000168036 ENSG00000164690 ENSG00000168610 PMC10520887__F9 Porcine IKKE is involved in the STING-induced type I IFN antiviral response of the cytosolic DNA signaling pathway ENSG00000183735 ENSG00000164430 PMC4236746__F3 Largest key pathway obtained for the colorectal cancer case study ENSG00000117154 ENSG00000277586 ENSG00000016490 ENSG00000110395 ENSG00000100285 ENSG00000204103 ENSG00000182944 ENSG00000177606 ENSG00000276833 ENSG00000165702 ENSG00000185149 ENSG00000159788 PMC7223841__F4 NAD+ homeostasis in renal health and disease ENSG00000162882 ENSG00000183077 PMC3829926__F1 Phosphatidylinositol 5-phosphate is a second messenger important for cell migration ENSG00000124102 ENSG00000100330 ENSG00000115020 PMC4695805__F2 Mitochondrial dysfunction caused by inhibition of pyruvate transfer to mitochondria ENSG00000067992 ENSG00000005882 PMC11922957__F5 Mechanisms of the Draconis Resina on Cardiovascular Diseases ENSG00000127445 ENSG00000162692 ENSG00000073756 ENSG00000168610 ENSG00000122194 PMC11922957__F3 Multiple Pathways of Draconis Resina Treating MIRI ENSG00000168036 ENSG00000189403 PMC5874668__F4 Angiotensin peptides are derived from the precursor protein angiotensinogen through several enzymatic conversion pathways ENSG00000175054 ENSG00000019991 ENSG00000130234 PMC5788303__F1 Activation of the lipid signaling pathway by GluN1/GluN2A receptor and the creation of transporter mediated drug resistance ENSG00000118777 PMC11978822__F1 MPDOLs for treating primary lung tumors and brain metastases in NSCLC ENSG00000146648 ENSG00000136231 PMC3944267__F8 Proposed mechanism for the differential response of tenocytes to oxidative stress under different extracellular glucose concentrations ENSG00000125398 ENSG00000150907 PMC8582496__F4 Dual Effect of the BMP9–ALK1 Pathway in Blood Vessels: An Opportunity for Cancer Therapy Improvement? ENSG00000170365 ENSG00000125968 PMC5099257__F6 Multiple signal transduction pathways and transcriptional networks during cold acclimation in D ENSG00000164151 ENSG00000110395 ENSG00000099246 PMC6572835__F7 Caveolin-1 promotes invasion and metastasis by upregulating Pofut1 expression in mouse hepatocellular carcinoma ENSG00000101346 ENSG00000185591 PMC9399075__F1 Lard Works in Mysterious Ways: Ceramides in Nutrition-Linked Chronic Disease ENSG00000139624 ENSG00000100422 ENSG00000063176 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000119537 ENSG00000148154 ENSG00000102172 ENSG00000143418 PMC9399075__F2 Lard Works in Mysterious Ways: Ceramides in Nutrition-Linked Chronic Disease ENSG00000223802 ENSG00000172292 ENSG00000143418 PMC5679454__F4 Tissue force programs cell fate and tumor aggression ENSG00000163914 PMC9343627__F1 Activation of STING Based on Its Structural Features ENSG00000183735 ENSG00000213928 ENSG00000164430 ENSG00000115415 PMC8080439__F1 Antiphospholipid syndrome: Complement activation, complement gene mutations, and therapeutic implications ENSG00000291559 ENSG00000134982 ENSG00000166278 ENSG00000182326 ENSG00000236625 PMC5437952__F3 Cholesterol metabolism controls plasmacytoid dendritic cell (PDC) innate functions ENSG00000239732 ENSG00000130164 ENSG00000169710 ENSG00000160179 ENSG00000276561 PMC4605830__F3 Phosphoproteins down-regulated in PCP and PCPPPI compared to Sal and SalPPI, respectively, which were significantly enriched in LTP signaling pathway ENSG00000176884 ENSG00000005339 ENSG00000148660 ENSG00000102081 ENSG00000166501 ENSG00000198576 ENSG00000276429 ENSG00000169032 PMC4961996__F2 Transmembrane signaling by TGFB ENSG00000198742 ENSG00000198793 PMC5437952__F2 Metabolic changes in plasmacytoid dendritic cells (PDC) providing energy and affecting their innate immune functions: glycolysis versus fatty acid oxidation coupled with OXPHOS ENSG00000239732 ENSG00000276561 ENSG00000142166 PMC8960635__F3 Hyaluronan, a double-edged sword in kidney diseases ENSG00000170961 ENSG00000168610 PMC7920247__F1 PTEN and PI3K/Akt signaling pathway ENSG00000138798 PMC6433975__F2 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis of T cell receptor signaling pathway in asthma ENSG00000110395 ENSG00000213658 ENSG00000117091 ENSG00000010810 ENSG00000135446 ENSG00000163599 ENSG00000113263 PMC10530615__F1 Starving the Beast: Limiting Coenzyme A Biosynthesis to Prevent Disease and Transmission in Malaria ENSG00000138621 ENSG00000127125 PMC4170638__F6 Galectin-4 expression is associated with reduced lymph node metastasis and modulation of Wnt/Beta-catenin signalling in pancreatic adenocarcinoma ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000168610 PMC7772395__F2 This figure displays a suggested relationship between coagulation and inflammation in patients with a SARS-CoV-2-infection ENSG00000115008 ENSG00000134982 ENSG00000173599 ENSG00000184012 ENSG00000122194 PMC9555118__F3 Periostin: biology and function in cancer ENSG00000134982 ENSG00000138798 ENSG00000168487 ENSG00000168036 ENSG00000146648 PMC5138853__F6 Cancer-associated fibroblasts treated with cisplatin facilitates chemoresistance of lung adenocarcinoma through IL-11/IL-11R/STAT3 signaling pathway ENSG00000137070 ENSG00000168610 PMC7223841__F2 NAD+ homeostasis in renal health and disease ENSG00000105835 ENSG00000278488 ENSG00000112992 PMC8126620__F1 Naturally Occurring Genetic Alterations in Proximal TCR Signaling and Implications for Cancer Immunotherapy ENSG00000291603 ENSG00000213658 ENSG00000010810 ENSG00000141968 PMC6652073__F6 Proposed models of the CoQ10biosynthetic pathway in mammals showing two alternative sequences of reactions (the decaprenyl chain is abbreviated as R) ENSG00000132423 ENSG00000119723 ENSG00000110871 ENSG00000173085 ENSG00000167186 PMC7354282__F2 Role of the farnesoid X receptor (FXR) and bile acids ENSG00000175054 ENSG00000130208 ENSG00000138207 ENSG00000134982 ENSG00000120885 ENSG00000158874 ENSG00000146648 PMC8642280__F4 How alcohol affects insulin‐like growth factor‐1's influences on the onset of puberty: A critical review ENSG00000169047 ENSG00000198793 ENSG00000102104 PMC7818184__F4 VPS4B affects tooth development‐related gene expression through Wnt/B‐catenin pathway ENSG00000119541 ENSG00000134982 ENSG00000168036 ENSG00000101421 PMC7190874__F10 Liver analysis ENSG00000150991 PMC6895966__F4 Functional interactions network analysis of co-occurring mutations in pre-NAC samples ENSG00000070831 ENSG00000173039 ENSG00000163918 ENSG00000035928 ENSG00000160691 ENSG00000100632 ENSG00000110395 ENSG00000168214 ENSG00000132383 ENSG00000133961 ENSG00000139687 ENSG00000132341 ENSG00000100603 PMC7354282__F4 Renal diseases ENSG00000113905 ENSG00000134982 ENSG00000145192 ENSG00000145321 ENSG00000244731 ENSG00000132693 ENSG00000062485 ENSG00000236625 ENSG00000106927 PMC5894800__F1 Enzymes and binding proteins involved in vitamin A and retinoic acid metabolism ENSG00000095596 ENSG00000121207 ENSG00000003137 PMC6708892__F4 The mechanisms involved in the transformation from NSCLC to SCLC ENSG00000136997 ENSG00000139687 PMC6251040__F1 Three modes of programmed cell death ENSG00000198793 ENSG00000120868 ENSG00000168404 ENSG00000026103 PMC4577049__F1 Up-regulation of the inflammatory response biofunction in Rwandan adults during mild malaria compared with day 30 of convalescence ENSG00000174125 ENSG00000152409 ENSG00000204103 ENSG00000151835 ENSG00000104972 ENSG00000148926 ENSG00000186818 ENSG00000158869 ENSG00000105205 ENSG00000173369 ENSG00000275404 ENSG00000145839 ENSG00000173372 ENSG00000102245 ENSG00000134243 ENSG00000100985 ENSG00000073861 ENSG00000186832 PMC6571119__F3 Possible interactions between ASD causal genes and RA signaling ENSG00000109101 ENSG00000142599 ENSG00000169760 ENSG00000069667 PMC3241725__F2 Bacterial manipulation of mitochondrial cell death pathways ENSG00000132906 ENSG00000002330 ENSG00000073578 ENSG00000171791 ENSG00000146648 ENSG00000164305 PMC8080831__F3 Core components of the Hippo-YAP pathway ENSG00000129474 ENSG00000083857 ENSG00000113645 ENSG00000186575 ENSG00000139926 ENSG00000150457 ENSG00000131023 PMC3241725__F3 Bacterial manipulation of host pro-survival pathway ENSG00000171791 ENSG00000106100 ENSG00000164305 PMC6571119__F4 ASD causal genes affecting BMP signaling and potential crosstalk with other signaling pathways ENSG00000102081 ENSG00000164690 PMC2903433__F4 Chloride Regulation in the Pain Pathway ENSG00000196632 ENSG00000126562 ENSG00000143867 ENSG00000060237 ENSG00000220205 PMC11677427__F4 Under physiological conditions, insulin binding to its receptor (IR), which is auto phosphorylated at Tyr residues and consequently promotes the phosphorylation of its substrate, insulin receptor substrate 1 (IRS1), activates the signaling pathway ENSG00000197081 ENSG00000140575 ENSG00000169047 PMC9379893__F3 Integration of mechanotransduction pathways and innate immune cell activation ENSG00000150782 ENSG00000108691 ENSG00000196588 ENSG00000103335 PMC9379893__F1 An overview of mechanotransduction pathways in cells ENSG00000196588 ENSG00000291971 ENSG00000103335 PMC7460590__F2 Overall signaling cascades, including the TGF-beta SMAD cascade (reproduced with permission of Reactome Pathway, Fabregat et al ENSG00000198793 ENSG00000163914 PMC4861870__F3 Cellular innate response to rotavirus infection ENSG00000088888 ENSG00000115415 ENSG00000276561 ENSG00000164342 PMC7460590__F4 TSP-1-CD36 signaling is inducing apoptosis of tumor associated epithelial cells ENSG00000135218 ENSG00000026103 PMC9673340__F9 N6-methyladenosine-mediated SH3BP5-AS1 upregulation promotes GEM chemoresistance in pancreatic cancer by activating the Wnt signaling pathway ENSG00000091542 ENSG00000164949 PMC6359026__F3 Estrogen signaling pathways in cancer ENSG00000291971 ENSG00000113070 ENSG00000171791 ENSG00000146648 PMC6947155__F1 Schematic representation summarizing the main extrinsic (cell–cell contact and growth factors) signals that regulate the Hippo-YAP (Yes-associated protein) pathway ENSG00000198670 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC7106920__F1 Relationship between PCOS and immune cells ENSG00000169245 ENSG00000132478 ENSG00000080166 PMC6947155__F2 Hippo Pathway and YAP Signaling Alterations in Squamous Cancer of the Head and Neck ENSG00000083857 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC3388731__F5 Canonical Hedgehog signaling ENSG00000136997 ENSG00000128602 PMC7072820__F7 MiR-202-5p-mediated SF1 regulation of the canonical TGFB signaling pathway in GCs ENSG00000168066 PMC8837817__F1 Cholinergic anti-inflammatory pathway ENSG00000125538 ENSG00000136869 ENSG00000168610 ENSG00000274542 PMC12124646__F3 Schematic of the mechanism of NMs-mediated SCs in PNR ENSG00000197971 ENSG00000198793 ENSG00000168610 PMC5817803__F2 ALK signaling pathway ENSG00000002330 ENSG00000198793 ENSG00000128602 PMC9170953__F4 Diverse Roles of NETosis in the Pathogenesis of Lupus ENSG00000239732 ENSG00000189403 PMC7275233__F2 Curcumin-induced apoptotic pathway in human ENSG00000149311 ENSG00000175054 ENSG00000168040 PMC12124646__F5 Mechanisms mediated by NMs that influence macrophage functionality in PNR ENSG00000260314 ENSG00000198793 ENSG00000118520 PMC11538887__F8 Mechanism of exosome treatment of androgenetic alopecia ENSG00000091972 ENSG00000132646 PMC12027666__F2 S1P-mediated signaling pathways ENSG00000291971 ENSG00000163914 ENSG00000170989 ENSG00000180739 ENSG00000125910 ENSG00000168610 ENSG00000267534 ENSG00000183018 PMC11011983__F1 Alterations in Proteostasis Mechanisms in Niemann–Pick Type C Disease ENSG00000141458 PMC12027666__F1 Sphingolipid synthesis pathways ENSG00000100422 ENSG00000102172 PMC7040395__F7 LGK974 on ccRCC ENSG00000281324 ENSG00000162337 ENSG00000102312 ENSG00000168036 PMC9329277__F4 Integrated genomic sequencing in myeloid blast crisis chronic myeloid leukemia (MBC-CML), identified potentially important findings in the context of leukemogenesis model ENSG00000149311 ENSG00000171456 ENSG00000156531 ENSG00000274442 ENSG00000179348 ENSG00000139618 ENSG00000179295 ENSG00000183765 PMC8585665__F1 Major Ca2+-dependent pathways that could be affected by genes mutated in B-cell lymphomas (Table ) ENSG00000105369 ENSG00000172578 ENSG00000107562 ENSG00000007312 ENSG00000171791 ENSG00000267534 ENSG00000182162 ENSG00000010671 ENSG00000121966 ENSG00000239732 ENSG00000186716 ENSG00000104290 ENSG00000136869 ENSG00000172936 ENSG00000026103 PMC11788002__F1 Galactose metabolism and proposed pathophysiology PMC11851696__F7 Expression profiles of DEGs in pathways related to IAA, GA, and ABA hormones and reactive oxygen species accumulation PMC5993623__F2 Recycling endosome and bacterial pathogens ENSG00000170011 ENSG00000026508 ENSG00000136869 PMC4849425__F2 Immunomediated Pan-cancer Regulation Networks are Dominant Fingerprints After Treatment of Cell Lines with Demethylation ENSG00000245848 ENSG00000019991 ENSG00000277263 ENSG00000142273 PMC7653241__F1 S‐adenosylmethionine (SAM) biosynthesis and metabolism PMC4684384__F5 Brazilian Red Propolis Attenuates Inflammatory Signaling Cascade in LPS-Activated Macrophages ENSG00000170458 ENSG00000125538 ENSG00000172936 ENSG00000150455 PMC7453842__F1 Schematic depicting pantothenate uptake and transformation into CoA through the CoA biosynthetic pathway ENSG00000138621 ENSG00000127125 PMC9238361__F2 Sirtuin Family and Diabetic Kidney Disease ENSG00000187531 ENSG00000180773 ENSG00000221955 ENSG00000278488 ENSG00000262217 ENSG00000077463 ENSG00000103257 ENSG00000142082 ENSG00000172940 ENSG00000283100 ENSG00000124523 ENSG00000008130 ENSG00000096717 ENSG00000089163 PMC6128695__F1 Epigenetic regulation of Fgf1 transcription by CRTC1 and memory enhancement ENSG00000174576 ENSG00000198576 ENSG00000105662 PMC7316886__F3 Dysregulated IFN responses in COPD airway epithelial cells ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000096717 ENSG00000142166 PMC4104445__F1 Life in the bile duct ENSG00000123975 ENSG00000198901 ENSG00000140835 ENSG00000156970 ENSG00000108375 ENSG00000136869 ENSG00000185008 ENSG00000112742 ENSG00000117399 PMC8226258__F5 X-Inactive-Specific Transcript: Review of Its Functions in the Carcinogenesis ENSG00000169554 ENSG00000138336 ENSG00000026508 ENSG00000168036 ENSG00000100985 ENSG00000118777 ENSG00000136826 ENSG00000125084 PMC6912580__F3 Molecular pathways regarding neuronal survival on which QC seems to assess their effects within the brain ENSG00000198793 PMC7316886__F2 Innate immune responses of airway epithelial cells to RV ENSG00000169245 ENSG00000183735 ENSG00000088888 ENSG00000161921 ENSG00000163739 ENSG00000169429 ENSG00000172936 ENSG00000131323 ENSG00000125347 ENSG00000175104 ENSG00000007171 PMC6422901__F2 Schematic for arachidonic acid (AA) pathway: phospholipids from the plasma membrane are mobilized and converted to AA by phospholipase A2 (PLA2) enzyme activity ENSG00000283887 PMC6422901__F3 EP receptors and their downstream signaling: PGE2 binds to its cognate receptors, the E-series of prostaglandin receptors (EP1–EP4) on the plasma membrane and nuclear membrane ENSG00000176692 ENSG00000291971 ENSG00000168036 PMC3132735__F7 CCN2 Is Required for the TGFB Induced Activation of Smad1 - Erk1/2 Signaling Network ENSG00000151702 ENSG00000170365 ENSG00000291971 PMC8914027__F7 Emerging Roles of lncRNAs Regulating RNA-Mediated Type-I Interferon Signaling Pathway ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000101883 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000121060 ENSG00000164342 ENSG00000142166 PMC8914027__F5 Emerging Roles of lncRNAs Regulating RNA-Mediated Type-I Interferon Signaling Pathway ENSG00000183735 ENSG00000125826 ENSG00000123240 ENSG00000088888 ENSG00000167325 ENSG00000171848 ENSG00000138777 ENSG00000131323 PMC5736021__F2 PI3K signaling pathway ENSG00000002330 PMC4918391__F2 HVJ-E-mediated cancer cell death.Notes: (A) HVJ-E-mediated apoptosis signaling in cancer cells with CASP8 ENSG00000132906 ENSG00000088888 ENSG00000064012 ENSG00000164305 ENSG00000276561 PMC8914027__F6 Emerging Roles of lncRNAs Regulating RNA-Mediated Type-I Interferon Signaling Pathway ENSG00000213928 ENSG00000105397 ENSG00000125347 ENSG00000129351 PMC6422901__F4 Combating inflammation promoted by KSHV infection: KSHV infection promotes pro-inflammatory lipid mediators of arachidonic acid pathway and the enzymes involved in their synthesis ENSG00000087245 ENSG00000291971 ENSG00000112715 ENSG00000150630 PMC8914027__F3 Emerging Roles of lncRNAs Regulating RNA-Mediated Type-I Interferon Signaling Pathway ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000121060 PMC8914027__F4 Emerging Roles of lncRNAs Regulating RNA-Mediated Type-I Interferon Signaling Pathway ENSG00000183735 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC9146201__F1 Targeting Energy Metabolism in Cancer Treatment ENSG00000159399 PMC2990476__F3 Functional network identified by genes in the single nucleotide polymorphism (SNP) component using independent component analysis ENSG00000113504 ENSG00000100100 PMC8914027__F1 Emerging Roles of lncRNAs Regulating RNA-Mediated Type-I Interferon Signaling Pathway ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000121060 ENSG00000164342 ENSG00000142166 PMC9560141__F5 Similarities and differences in circadian control of transcript accumulation in key genes involved in primary metabolism and signalling PMC8438069__F6 Itaconic acid exerts anti-inflammatory and antibacterial effects via promoting pentose phosphate pathway to produce ROS ENSG00000049239 ENSG00000125538 PMC7395714__F1 Surface expression of PD-1, PD-L1 and CTLA-4 ENSG00000091317 ENSG00000183723 ENSG00000131446 ENSG00000143761 ENSG00000198589 ENSG00000198846 PMC3180107__F1 Intrinsic and extrinsic pathways of apoptosis ENSG00000132906 ENSG00000168040 ENSG00000164305 PMC6477581__F1 microRNA-Mediated Tumor–Microbiota Metabolic Interactions in Colorectal Cancer ENSG00000198793 ENSG00000169710 PMC3180107__F2 Molecular mechanism of autophagy and its role in cell death and survival ENSG00000198382 ENSG00000002330 ENSG00000198793 PMC9666758__F3 Baicalin regulates stem cells as a creative point in the treatment of climacteric syndrome ENSG00000126016 ENSG00000186575 ENSG00000160867 ENSG00000169435 PMC3035032__F3 Simplified schematic illustrating molecular mechanisms of neurite regulation ENSG00000070831 ENSG00000010810 ENSG00000163914 ENSG00000168610 ENSG00000106078 PMC2430620__F1 Broccoli Consumption Interacts with GSTM1 to Perturb Oncogenic Signalling Pathways in the Prostate ENSG00000105329 ENSG00000138798 PMC10497558__F3 BCAAs metabolism in Cancer ENSG00000144895 ENSG00000060982 ENSG00000198793 ENSG00000162607 ENSG00000089163 ENSG00000105552 PMC3143906__F3 Multiple factors and pathways affect insulin-like growth factor 1 (IGF1)-Akt signaling PMC10497558__F5 Aspartate, Arginine and Methionine metabolism ENSG00000099810 ENSG00000036473 ENSG00000070669 ENSG00000116984 PMC10497558__F6 Aspartate metabolism in solid tumor ENSG00000177542 ENSG00000128272 ENSG00000004864 ENSG00000126804 ENSG00000070669 PMC7690754__F17 Pathways involved in BCC pathogenesis ENSG00000164161 ENSG00000148400 ENSG00000138798 ENSG00000150457 ENSG00000128602 ENSG00000131023 PMC10497558__F8 Arginine metabolism in tumor cells ENSG00000081181 ENSG00000139514 ENSG00000118520 ENSG00000168610 PMC2570554__F4 Anti-apoptotic mechanism of survival and growth of serum-starved 5637 human bladder carcinoma cells ENSG00000019991 ENSG00000002330 ENSG00000110395 ENSG00000291971 ENSG00000113070 PMC8290157__F1 RNA Polymerase III, Ageing and Longevity ENSG00000101751 ENSG00000136997 ENSG00000179632 ENSG00000166169 PMC4271744__F1 Network analysis of genes significantly modulated in response to mood stabilisers ENSG00000130522 PMC3762125__F5 Synergy between RasGRP and SOS in TCR signaling ENSG00000213658 ENSG00000124181 PMC7918750__F3 Human cytomegalovirus (HCMV) factors that contribute to latency maintenance ENSG00000138386 ENSG00000174059 ENSG00000135503 PMC7918750__F4 Human cytomegalovirus (HCMV) microRNA- (miRNA)-mediated reactivation from latency ENSG00000146648 PMC10963930__F0 An active form of vitamin D, calcitriol, directly enhances the expression of Rspo2 by binding to the vitamin D receptor (VDR) ENSG00000134569 ENSG00000030304 ENSG00000165917 PMC2707261__F1 Regulation of glycolysis, glutaminolysis and de novo nucleotide biosynthesis in tumor cells ENSG00000291971 PMC7900187__F2 Immune cell amino acid metabolism following mycobacterial infection ENSG00000081181 ENSG00000118520 PMC7999836__F1 Metabolic pathway of PC and TG synthesis ENSG00000042832 ENSG00000173599 ENSG00000198670 ENSG00000026103 PMC4077819__F5 Inhibition of C3 Convertase Activity by Hepatitis C Virus as an Additional Lesion in the Regulation of Complement Components ENSG00000166278 ENSG00000236625 PMC9137834__F4 Oxidative Stress in Cancer Immunotherapy: Molecular Mechanisms and Potential Applications ENSG00000198793 ENSG00000077782 ENSG00000168610 ENSG00000079999 PMC2894844__F7 Schematic drawing of Akt/GSK-3B/tau signaling ENSG00000005882 PMC6895847__F2 The unfolded protein response (UPR) and its connection to cell death ENSG00000128272 ENSG00000144895 ENSG00000168040 ENSG00000127191 PMC4519949__F2 Proposed effects of salubrinal on the xenotoxicant-activated ER stress signaling pathways ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC8422786__F2 Wnt signaling pathway in tumorigenesis, pharmacological targets, and drug development for cancer therapy ENSG00000134982 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC3226689__F7 Hole-in-One Mutant Phenotypes Link EGFR/ERK Signaling to Epithelial Tissue Repair in Drosophila ENSG00000146648 PMC3428335__F8 Master Regulators in the Metabolic/Transcriptional Coupling in Breast Carcinomas ENSG00000160752 ENSG00000110921 ENSG00000112972 ENSG00000001630 ENSG00000152904 ENSG00000172893 ENSG00000149809 ENSG00000113161 ENSG00000104549 ENSG00000167508 PMC2828273__F1 Interconnections between p53 and IGF-1/AKT/mTOR pathways ENSG00000005882 PMC5852411__F2 NHERF1 pathways ENSG00000168036 ENSG00000146648 PMC4516163__F1 Numerous arrestin functions play a role in apoptosis and cell survival ENSG00000002330 PMC3426219__F2 Chondroitin sulfate proteoglycan 4 (CSPG4) Signaling Pathways ENSG00000019991 ENSG00000087245 ENSG00000173546 PMC4809875__F1 Reelin signaling pathway in adult synaptic plasticity ENSG00000010810 ENSG00000198793 ENSG00000173406 PMC4337036__F2 Schematic overview of intracellular antiviral immune signaling in teleosts ENSG00000183735 ENSG00000187608 ENSG00000160710 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC6572125__F5 Enriched integrin signaling pathway in non-type subtype of bladder carcinoma cell lines ENSG00000165983 ENSG00000070831 ENSG00000291971 ENSG00000010810 ENSG00000132478 ENSG00000137076 ENSG00000099942 ENSG00000146648 ENSG00000089159 ENSG00000197702 PMC3098223__F1 Integrative Analysis of Transgenic Alfalfa (Medicago sativa L.) Suggests New Metabolic Control Mechanisms for Monolignol Biosynthesis ENSG00000121807 ENSG00000084774 PMC9339597__F2 Complement System in Metabolic-Associated Kidney Diseases ENSG00000039537 ENSG00000244731 ENSG00000166278 PMC6152404__F6 Proposed mechanism for the proliferation inhibitory effects of ART in HCT116 cells ENSG00000169710 ENSG00000197142 ENSG00000105656 PMC9577175__F1 Activation of NOD1 and NOD2 in the development of liver injury and cancer ENSG00000167207 ENSG00000162601 ENSG00000175104 ENSG00000106100 PMC10158519__F7 Schematic diagram by GroA promotes of expressions of inflammatory mediator TNFA and COX-2 by activating NOD1/RIPK2-mediated JNK, ERK and p38 MAPK pathways in HNSCC progression and metastasis ENSG00000163464 ENSG00000106100 PMC4622660__F1 Canonical Wnt/Beta-catenin signaling pathway: OFF state ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC11899831__F3 Mechanotransduction in tumor cells: sensing and transducing mechanical signals from the ECM into intracellular biochemical signals ENSG00000291971 ENSG00000150457 ENSG00000131023 PMC7144542__F1 NFKB and MAPK signaling pathway in lumpfish ENSG00000087095 ENSG00000172680 ENSG00000107562 ENSG00000242689 ENSG00000138798 ENSG00000173039 ENSG00000081189 ENSG00000010671 ENSG00000095585 ENSG00000149311 ENSG00000170458 ENSG00000125538 ENSG00000107201 ENSG00000164949 ENSG00000101425 PMC3064559__F3 Interconnectivity of signaling pathways emanating from TLRs and TACI ENSG00000082512 ENSG00000172936 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC2846630__F1 Regulation of the mTOR pathway by nutrients (amino acids, glucose), stress and insulin/IGF-1 ENSG00000069482 ENSG00000169047 ENSG00000155792 ENSG00000164327 PMC3126020__F1 Hedgehog signaling pathway in vertebrates ENSG00000106571 ENSG00000128602 PMC2194118__F6 Molecular dissection of the signaling cascade underlying BCR-controlled integrin A4B1-mediated adhesion ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000197943 ENSG00000010671 PMC3126020__F2 Targeting the Hedgehog pathway in cancer ENSG00000171791 ENSG00000128602 PMC3461241__F3 Network analysis suggests an immune response and inflammation in ulcerative tissue and non-ulcerative tissue of patients with ulcerative interstitial cystitis (IC) ENSG00000243414 ENSG00000116701 ENSG00000043462 ENSG00000276561 ENSG00000141968 ENSG00000010671 ENSG00000110395 ENSG00000213658 ENSG00000120899 ENSG00000263528 ENSG00000163131 ENSG00000074966 ENSG00000172936 ENSG00000113263 ENSG00000124181 ENSG00000143184 PMC4790538__F3 Gene–gene networks generated by pathway analysis.Notes: The networks were generated through the use of QIAGEN’s Ingenuity Pathway Analysis (IPA®, QIAGEN Redwood City, www.qiagen.com/ingenuity) ENSG00000178999 ENSG00000291971 ENSG00000154001 ENSG00000167513 ENSG00000150687 ENSG00000171791 ENSG00000093009 ENSG00000137807 ENSG00000131242 ENSG00000082175 ENSG00000148773 ENSG00000089685 ENSG00000291948 ENSG00000171241 ENSG00000135336 ENSG00000137267 ENSG00000105672 ENSG00000115163 ENSG00000101057 ENSG00000137872 ENSG00000132478 ENSG00000154447 ENSG00000198901 ENSG00000134057 ENSG00000116106 ENSG00000171848 ENSG00000153066 ENSG00000197555 ENSG00000176619 PMC10255416__F7 Supplementation affects metabolic reprogramming of cumulus cells in aging ovarian patients ENSG00000074800 ENSG00000073578 ENSG00000100412 ENSG00000117118 ENSG00000146701 ENSG00000159399 ENSG00000062485 PMC4917114__F7 An Integrative Transcriptomic Analysis for Identifying Novel Target Genes Corresponding to Severity Spectrum in Spinal Muscular Atrophy ENSG00000018236 ENSG00000141448 ENSG00000171791 ENSG00000073756 PMC4918724__F5 Integrated microRNA, gene expression and transcription factors signature in papillary thyroid cancer with lymph node metastasis ENSG00000143252 ENSG00000065518 ENSG00000073578 ENSG00000138495 ENSG00000117118 ENSG00000119013 PMC7443001__F3 Localization of 38 DEGs in the MAPK signaling pathway ENSG00000157764 ENSG00000109320 ENSG00000102871 ENSG00000269335 ENSG00000213341 ENSG00000155903 ENSG00000127191 ENSG00000081189 ENSG00000197461 ENSG00000177189 ENSG00000160867 ENSG00000141480 ENSG00000143507 ENSG00000136997 ENSG00000130222 ENSG00000175104 ENSG00000026103 PMC7443001__F4 Interactions among 38 DEGs involved in the MAPK signaling pathway ENSG00000157764 ENSG00000109320 ENSG00000102871 ENSG00000269335 ENSG00000213341 ENSG00000155903 ENSG00000127191 ENSG00000081189 ENSG00000197461 ENSG00000177189 ENSG00000160867 ENSG00000141480 ENSG00000136997 ENSG00000130222 ENSG00000077782 ENSG00000026103 PMC7607189__F1 miRNA-1183-targeted regulation of Bcl-2 contributes to the pathogenesis of rheumatic heart disease ENSG00000281766 ENSG00000117525 ENSG00000213658 ENSG00000156127 ENSG00000126705 ENSG00000106483 ENSG00000143228 ENSG00000168040 PMC6537587__F1 Soluble amylin and pramlintide are capable of activating the endogenous AMYR which is responsible for recruiting adenylate cyclase ENSG00000084774 PMC4337782__F1 Manufacturing neurons from human embryonic stem cells: biological and regulatory aspects to develop a safe cellular product for stroke cell therapy ENSG00000138798 ENSG00000128342 ENSG00000164690 PMC182218__F2 Osteoblasts express components necessary for coordinating mineralization of ECM and phosphate handling by the kidney ENSG00000118972 ENSG00000152266 ENSG00000168036 PMC7370084__F3 Four p38 MAPK isoforms are p38A, p38B, p38G, and p38D ENSG00000167658 PMC9676924__F3 CD160 receptor in CLL: Current state and future avenues ENSG00000168610 PMC7370084__F4 P38 MAPK signaling pathways ENSG00000144895 ENSG00000115415 ENSG00000163914 ENSG00000136997 ENSG00000284161 ENSG00000172936 ENSG00000175104 ENSG00000127191 ENSG00000123268 PMC7370084__F1 Summary of the signal transduction pathways through which acupuncture treats nervous system diseases ENSG00000002330 ENSG00000115415 ENSG00000136997 ENSG00000172936 ENSG00000136869 ENSG00000123268 PMC8584200__F3 Rho/ROCK Pathway and Noncoding RNAs: Implications in Ischemic Stroke and Spinal Cord Injury ENSG00000141867 ENSG00000075213 PMC6334985__F7 Retinal phosphoproteome ENSG00000182901 ENSG00000171723 ENSG00000166402 ENSG00000198691 ENSG00000168615 ENSG00000134160 ENSG00000187672 ENSG00000172037 ENSG00000114349 ENSG00000129221 ENSG00000163914 ENSG00000175544 ENSG00000186765 ENSG00000197386 ENSG00000291761 ENSG00000164318 ENSG00000109103 ENSG00000170289 ENSG00000102104 ENSG00000166569 ENSG00000139687 ENSG00000042781 ENSG00000134376 ENSG00000277707 ENSG00000127928 ENSG00000105392 ENSG00000112619 ENSG00000078369 ENSG00000132518 ENSG00000104237 ENSG00000167468 ENSG00000149489 ENSG00000125533 ENSG00000125124 ENSG00000119715 ENSG00000114115 ENSG00000136936 PMC8652208__F3 Endocrine Regulation of Extra-skeletal Organs by Bone-derived Secreted Protein and the effect of Mechanical Stimulation ENSG00000118972 ENSG00000167941 PMC8652208__F2 Endocrine Regulation of Extra-skeletal Organs by Bone-derived Secreted Protein and the effect of Mechanical Stimulation ENSG00000118972 ENSG00000160867 ENSG00000167941 PMC3855681__F4 An Integrated Immune System Pathway in Homo sapiens and Its Interaction with Superantigen Producing Expression Regulatory Pathway in Staphylococcus aureus: Comparing Behavior of Pathogen Perturbed and Unperturbed Pathway ENSG00000291603 ENSG00000110395 ENSG00000213658 ENSG00000070831 ENSG00000010810 ENSG00000135446 ENSG00000163599 ENSG00000163914 ENSG00000177606 ENSG00000113520 ENSG00000113263 ENSG00000113525 PMC10919309__F4 Elucidating the role of Rhodiola rosea L. in sepsis-induced acute lung injury via network pharmacology: emphasis on inflammatory response, oxidative stress, and the PI3K-AKT pathway ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000136997 PMC7210457__F5 BT87Q-Globin Gene Therapy Reduces Sickle Hemoglobin Production, Allowing for Ex Vivo Anti-sickling Activity in Human Erythroid Cells ENSG00000128165 ENSG00000167693 ENSG00000178078 ENSG00000116106 ENSG00000177238 ENSG00000135069 ENSG00000174059 ENSG00000180730 ENSG00000277276 ENSG00000285069 ENSG00000215788 ENSG00000158258 PMC7555965__F4 Molecular pathways involved in aCML ENSG00000078369 ENSG00000198793 ENSG00000152217 ENSG00000168610 ENSG00000061938 PMC8196501__F8 Photoactivation of TGFB/SMAD signaling pathway ameliorates adult hippocampal neurogenesis in Alzheimer’s disease model ENSG00000170365 ENSG00000120693 ENSG00000077279 ENSG00000131095 PMC10980228__F6 H. Model for the BCM mode of action ENSG00000182511 ENSG00000163914 ENSG00000135605 PMC4810618__F7 Selective upregulation of Mcl-1 and HSP27 during HCMV infection of monocytes ENSG00000291971 ENSG00000198793 ENSG00000146648 PMC6602950__F6 The rheostat model proposed for Notch signaling network ENSG00000168214 ENSG00000168610 PMC8471532__F6 Resveratrol as an Adjunctive Therapy for Excessive Oxidative Stress in Aging COVID-19 Patients ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC8471532__F8 Resveratrol as an Adjunctive Therapy for Excessive Oxidative Stress in Aging COVID-19 Patients ENSG00000130234 ENSG00000079999 PMC8471532__F9 Resveratrol as an Adjunctive Therapy for Excessive Oxidative Stress in Aging COVID-19 Patients ENSG00000100985 ENSG00000005381 ENSG00000096717 ENSG00000167419 PMC4460146__F10 The role of Sag in regulation of KrasG12D-induced papillomagenesis ENSG00000113558 ENSG00000112851 ENSG00000281857 PMC2724778__F3 Hypothesis-driven two-factor common pathway model path diagram of the metabolic syndrome ENSG00000042832 ENSG00000105516 ENSG00000166278 PMC5623081__F7 TLR2 Plays a Key Role in Platelet Hyperreactivity and Accelerated Thrombosis Associated with Hyperlipidemia ENSG00000135218 ENSG00000291971 ENSG00000197943 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC3973216__F4 Simplified representation of the regulation of actin cytoskeleton pathway and differentially regulated genes ENSG00000124102 ENSG00000163435 ENSG00000070831 ENSG00000181104 ENSG00000102678 ENSG00000054277 ENSG00000159788 PMC5355309__F10 25-Hydroxycholesterol is involved in the pathogenesis of amyotrophic lateral sclerosis ENSG00000138135 ENSG00000136869 PMC8971568__F1 Lipid Metabolism: Immune Regulation and Therapeutic Prospectives in Systemic Lupus Erythematosus ENSG00000042832 ENSG00000113161 ENSG00000169710 PMC8899363__F3 Niban apoptosis regulator 1 promotes gemcitabine resistance by activating the focal adhesion kinase signaling pathway in bladder cancer ENSG00000086589 ENSG00000072274 ENSG00000124491 ENSG00000112118 ENSG00000073111 ENSG00000166147 ENSG00000071282 ENSG00000274619 ENSG00000164764 ENSG00000182004 ENSG00000285049 ENSG00000145216 ENSG00000172172 ENSG00000168807 ENSG00000177575 ENSG00000164508 ENSG00000156232 ENSG00000130340 ENSG00000179041 ENSG00000135636 ENSG00000106803 ENSG00000130826 ENSG00000173933 ENSG00000169756 ENSG00000261236 ENSG00000143569 ENSG00000167721 ENSG00000137509 ENSG00000138207 ENSG00000260314 ENSG00000113905 ENSG00000175899 ENSG00000160688 ENSG00000291971 ENSG00000134575 ENSG00000110651 ENSG00000120697 ENSG00000166387 ENSG00000104833 ENSG00000197702 ENSG00000197256 ENSG00000112578 ENSG00000084463 ENSG00000120690 ENSG00000108861 ENSG00000115221 ENSG00000176014 ENSG00000139343 ENSG00000162924 ENSG00000073712 ENSG00000211445 ENSG00000149311 ENSG00000175416 ENSG00000167491 ENSG00000072110 ENSG00000110713 ENSG00000092841 PMC4110034__F1 Microbial Egress: A Hitchhiker's Guide to Freedom ENSG00000137275 ENSG00000168404 ENSG00000164305 ENSG00000285379 PMC1775040__F4 WNT Pathways ENSG00000134982 ENSG00000163914 PMC4561339__F1 Schematic diagram of the protein components involved in the myelin protein-derived inhibition of neurite growth ENSG00000169783 PMC8929360__F3 New insights into the role of melatonin in diabetic cardiomyopathy ENSG00000128272 ENSG00000144895 ENSG00000096717 PMC7031270__F6 IPA generated networks of transcription factors and differentiation markers ENSG00000164379 ENSG00000186395 ENSG00000134317 ENSG00000109101 ENSG00000148400 ENSG00000167768 ENSG00000276644 ENSG00000134760 ENSG00000285348 ENSG00000143631 ENSG00000163435 ENSG00000163207 ENSG00000177606 ENSG00000043039 PMC6179272__F6 Hippo signaling pathway in Duchenne muscular dystrophy ENSG00000180667 ENSG00000078747 ENSG00000150457 ENSG00000131023 PMC2517590__F2 Schematic overview of the integrin signaling ENSG00000070831 ENSG00000291971 ENSG00000099942 PMC8966131__F4 Association Between Gut Microbiota and Osteoarthritis: A Review of Evidence for Potential Mechanisms and Therapeutics ENSG00000170458 ENSG00000163661 PMC5127598__F5 Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000136997 ENSG00000123374 ENSG00000196470 ENSG00000164305 ENSG00000026103 PMC8821656__F1 Approaches Toward Targeting Matrix Metalloproteases for Prognosis and Therapies in Gynecological Cancer: MicroRNAs as a Molecular Driver ENSG00000092847 ENSG00000128191 ENSG00000113360 ENSG00000134698 ENSG00000123908 ENSG00000132341 PMC7443474__F3 Exploring microRNAs in diabetic chronic cutaneous ulcers: Regulatory mechanisms and therapeutic potential ENSG00000140443 PMC7573103__F3 Signaling pathways in TNBC targeted by multiple components of the MD oils ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198793 PMC7443474__F2 Exploring microRNAs in diabetic chronic cutaneous ulcers: Regulatory mechanisms and therapeutic potential ENSG00000123091 ENSG00000281324 ENSG00000181274 ENSG00000162337 ENSG00000134982 ENSG00000173120 ENSG00000109906 ENSG00000173039 ENSG00000168036 ENSG00000175104 ENSG00000184216 PMC9077270__F8 Alpha-synuclein inhibits Snx3-retromer retrograde trafficking of the conserved membrane-bound proprotein convertase Kex2 in the secretory pathway of Saccharomyces cerevisiae ENSG00000112335 ENSG00000111237 ENSG00000069329 PMC7289845__F1 Prenatal exposure to bisphenol A alters the transcriptome-interactome profiles of genes associated with Alzheimer’s disease in the offspring hippocampus ENSG00000091656 ENSG00000173141 ENSG00000132824 ENSG00000176049 ENSG00000119401 ENSG00000105298 ENSG00000169612 ENSG00000183690 ENSG00000168385 ENSG00000144362 ENSG00000161642 ENSG00000062194 ENSG00000127993 ENSG00000120256 ENSG00000010671 ENSG00000171606 ENSG00000088727 ENSG00000119929 ENSG00000128482 ENSG00000140299 PMC11493653__F2 MiRNAs in key phases of diabetic wound healing ENSG00000170962 ENSG00000168610 PMC7876257__F1 Figure summarizes the potential diet—epigenetic axis in T1DM development ENSG00000065559 PMC11493653__F3 LncRNAs in main phases of diabetic wound healing ENSG00000162711 ENSG00000115415 ENSG00000140545 ENSG00000112715 ENSG00000168610 PMC6402888__F2 Fatty Acid-Binding Protein 4 in Cardiovascular and Metabolic Diseases ENSG00000136869 ENSG00000026103 PMC11784099__F9 Antiviral activity of myricetin against pseudorabies virus through regulation of the type I interferon signaling pathway ENSG00000213928 ENSG00000164430 ENSG00000187608 ENSG00000089127 ENSG00000115415 ENSG00000276561 PMC9648792__F8 Comprehensive analysis of prognostic significance of cadherin (CDH) gene family in breast cancer ENSG00000177455 ENSG00000002330 ENSG00000070831 ENSG00000186716 ENSG00000198793 ENSG00000163914 ENSG00000113520 ENSG00000162924 ENSG00000198286 PMC3748736__F1 Hippo pathway in Drosophila (a) and mammals (b) ENSG00000166341 ENSG00000134376 ENSG00000186575 ENSG00000130545 ENSG00000109321 ENSG00000148204 ENSG00000139926 ENSG00000150457 PMC3108053__F1 Fanconi anemia pathway and ICL repair: implications for cancer therapy ENSG00000131944 ENSG00000149311 ENSG00000175054 ENSG00000144554 ENSG00000077152 ENSG00000108384 ENSG00000115392 PMC3255710__F2 Fine adjustment of autophagy by the AMPK-mTORC1-Ulk1/2 kinase network ENSG00000177169 ENSG00000110497 ENSG00000083290 ENSG00000198793 PMC11550943__F3 Metabolic pathways for a metabolism of glucose via the classical hexosamine pathway has a rate-limiting step at phosphofructose kinase (PFK1) that is inhibited by ATP, low pH and citrate ENSG00000140263 ENSG00000138030 PMC9675801__F1 SPATA2 at the level of TNF-RSC ENSG00000137275 ENSG00000102871 ENSG00000166278 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000064012 ENSG00000285379 PMC11877844__F6 Possible signaling pathways that are partially stimulated by hCG and induce the synthesis of proteins with cell fusion-activating properties ENSG00000123999 ENSG00000187688 ENSG00000115884 ENSG00000198793 ENSG00000197905 ENSG00000163993 ENSG00000137270 ENSG00000168036 ENSG00000159346 ENSG00000185591 ENSG00000162772 ENSG00000176387 PMC6142439__F2 Complement-mediated hemolysis in cold agglutinin disease ENSG00000166278 PMC6784137__F4 Interactions between autophagy and immunity in response to viral infection ENSG00000105656 ENSG00000172936 PMC3472459__F5 Coordinate regulation by NR signaling pathways of genes encoding enzymes in the de novo purine base biosynthesis pathway ENSG00000284320 ENSG00000128050 ENSG00000132170 PMC11510019__F3 Illustration of MEHHs’ phenolic acids regulating lipid metabolism pathways ENSG00000161533 ENSG00000113161 ENSG00000096717 ENSG00000026103 PMC8190078__F6 RANKL immunisation inhibits prostate cancer metastasis by modulating EMT through a RANKL-dependent pathway ENSG00000291971 ENSG00000168036 PMC11510019__F6 Illustration of MEHH phenolic acids mitigating oxidative stress by modulating various pathways ENSG00000128272 ENSG00000181019 PMC5550366__F1 Revisiting the Role of Wnt/Beta-catenin Signaling in Prostate Cancer ENSG00000134982 ENSG00000136997 PMC6442983__F7 Proposed model for the induction of the Vps34-autophagy pathway in ETV6 RUNX1-positive B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cells ENSG00000102145 ENSG00000198382 ENSG00000179348 PMC2825293__F2 Nutrient sensing machinery in K- and L-cells ENSG00000179002 ENSG00000159224 ENSG00000147262 PMC9658128__F4 Emerging Effects of IL-33 on COVID-19 ENSG00000239732 ENSG00000137033 ENSG00000125538 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC2749258__F3 Approaches to biomarkers in human colorectal cancer ENSG00000087095 ENSG00000156076 ENSG00000137673 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000105698 ENSG00000167346 ENSG00000112715 ENSG00000196628 ENSG00000165879 ENSG00000026508 ENSG00000112851 ENSG00000095002 ENSG00000175792 PMC11510019__F4 Depiction of how MEHHs phenolic acids regulate the insulin pathway ENSG00000169047 PMC11837477__F8 EGFR role in brain development ENSG00000113070 ENSG00000138798 ENSG00000164690 ENSG00000133961 ENSG00000168610 ENSG00000146648 PMC9658128__F2 Emerging Effects of IL-33 on COVID-19 ENSG00000081041 ENSG00000137033 ENSG00000163739 ENSG00000005381 PMC11510019__F5 Illustration of MEHHs’ phenolic acids mitigating the inflammatory response by modulating various pathways ENSG00000162711 ENSG00000172936 ENSG00000265972 ENSG00000162692 ENSG00000079999 PMC11837477__F9 EGFR role in T cell regulation ENSG00000111537 ENSG00000137033 ENSG00000109321 ENSG00000113070 ENSG00000138798 PMC11837477__F6 EGFR roles in bone development ENSG00000170365 ENSG00000163235 ENSG00000113070 ENSG00000198793 ENSG00000116690 ENSG00000146648 ENSG00000140443 PMC11837477__F4 EGFR roles in IECs proliferation and gut regeneration ENSG00000070831 ENSG00000109321 ENSG00000124882 ENSG00000168610 ENSG00000146648 PMC11837477__F5 EGFR roles in liver regeneration and fibrosis ENSG00000109321 ENSG00000163235 ENSG00000291971 ENSG00000113070 ENSG00000167910 ENSG00000168610 ENSG00000146648 PMC11837477__F2 EGFR ligands and signaling pathways activation ENSG00000110395 ENSG00000182585 ENSG00000109321 ENSG00000163235 ENSG00000291971 ENSG00000124882 ENSG00000113070 ENSG00000138798 ENSG00000146648 PMC11837477__F3 EGFR role in the placenta development ENSG00000087245 ENSG00000138798 ENSG00000170498 ENSG00000100985 ENSG00000283060 ENSG00000168610 ENSG00000146648 PMC4823347__F5 Molecular signaling partners of ROCK1 ENSG00000106683 ENSG00000067900 PMC8421605__F4 Effect of Gender to Fat Deposition in Yaks Based on Transcriptomic and Metabolomics Analysis ENSG00000149084 ENSG00000167114 ENSG00000170522 ENSG00000138029 ENSG00000206527 ENSG00000099194 ENSG00000120437 PMC3321152__F4 Non-apoptotic functions of apoptosis-regulatory proteins ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000285379 PMC4461888__F3 p38 MAPK signaling in osteoclasts ENSG00000162889 ENSG00000115415 ENSG00000175104 ENSG00000127191 ENSG00000131196 PMC4665627__F6 Deletion of SPARC Enhances Retinal Vaso-Obliteration in Mouse Model of Oxygen-Induced Retinopathy ENSG00000113140 ENSG00000128052 PMC8963791__F1 Pathways leading to generation of disease biomarkers in NPC ENSG00000119655 ENSG00000141458 PMC4444374__F1A Suppression of Antigen Presentation by IL-10 ENSG00000183735 ENSG00000172936 ENSG00000136869 ENSG00000184216 PMC4461888__F1 p38 MAPK signaling in chondrocytes ENSG00000081189 PMC4461888__F2 p38 MAPK signaling in osteoblasts ENSG00000152266 ENSG00000070831 ENSG00000102302 PMC4671655__F1 MiR-192-Mediated Positive Feedback Loop Controls the Robustness of Stress-Induced p53 Oscillations in Breast Cancer Cells ENSG00000100811 ENSG00000070831 PMC5587057__F2 Connectivity analysis of gene products differentially expressed by tissue type and menstrual phase ENSG00000157554 ENSG00000106025 ENSG00000110799 ENSG00000118526 ENSG00000109906 ENSG00000274736 ENSG00000137825 ENSG00000180644 ENSG00000104332 ENSG00000131477 ENSG00000171345 ENSG00000100385 ENSG00000111796 ENSG00000082175 ENSG00000064989 ENSG00000156298 ENSG00000197958 ENSG00000277236 ENSG00000150625 ENSG00000154654 ENSG00000283060 ENSG00000162747 ENSG00000203883 ENSG00000125968 ENSG00000163884 ENSG00000100079 ENSG00000104689 ENSG00000132329 ENSG00000104880 ENSG00000163947 ENSG00000131094 ENSG00000100450 ENSG00000007312 ENSG00000284161 ENSG00000106483 ENSG00000113088 ENSG00000009790 ENSG00000165061 ENSG00000166510 ENSG00000177614 ENSG00000147642 ENSG00000187801 ENSG00000104814 ENSG00000138642 ENSG00000010030 ENSG00000115523 ENSG00000124440 ENSG00000115461 PMC5794471__F4 Calcium signaling pathway ENSG00000156026 ENSG00000186716 ENSG00000148175 PMC5441531__F2 The circadian transcription/translation loop is comprised of rhythmically expressed “clock genes” ENSG00000005812 ENSG00000114999 PMC11208996__F1 Schematic graph illustrating the TGFB/Smad signaling pathway and its roles in the regulation of various biological processes during chronic kidney disease ENSG00000049768 ENSG00000135605 PMC3746560__F7 TG2-containing adhesive/signaling complexes on the cell surface ENSG00000281324 ENSG00000162337 ENSG00000291971 ENSG00000168036 PMC3357465__F1 Gene mutations involved in PTC carcinogenesis ENSG00000157764 PMC3653431__F2 Targeting the Hepcidin-Ferroportin Axis to Develop New Treatment Strategies for Anemia of Chronic Disease and Anemia of Inflammation ENSG00000170365 ENSG00000168610 PMC8285596__F8 Virilizing doses of testosterone decrease circulating insulin levels and differentially regulate insulin signaling in liver and adipose tissue of females ENSG00000171105 ENSG00000150907 ENSG00000169047 ENSG00000132170 PMC4299585__F10 Mechanisms underlining the sphingosine-1-phosphate (S1P)/sphingosine kinase 1 (SphK1)/S1P receptor (S1PR) 2 signaling axis in pulmonary arterial hypertension (PAH) ENSG00000171759 ENSG00000168610 ENSG00000267534 ENSG00000183018 PMC9289270__F1 LncRNA, an Emerging Approach for Neurological Diseases Treatment by Regulating Microglia Polarization ENSG00000138135 ENSG00000100345 ENSG00000172936 ENSG00000136869 PMC9289270__F2 LncRNA, an Emerging Approach for Neurological Diseases Treatment by Regulating Microglia Polarization ENSG00000162711 ENSG00000150782 ENSG00000148400 ENSG00000253352 ENSG00000168610 PMC7261723__F8 Proposed model for the role of Isc1 and Cdc55 in the HU-induced signaling pathway ENSG00000136425 ENSG00000134982 ENSG00000173599 ENSG00000117399 ENSG00000149503 PMC12192587__F5 Predicted Regulatory Networks Influencing Muscle Fiber Type Transition by ECM Coatings ENSG00000109320 ENSG00000291971 ENSG00000150907 ENSG00000129152 ENSG00000291761 ENSG00000081189 PMC8584317__F3 Progress of Signaling Pathways, Stress Pathways and Epigenetics in the Pathogenesis of Skeletal Fluorosis ENSG00000198793 PMC2975074__F3 Cell stress response: activation of the aggresome pathway, HSPs, and transcriptional response ENSG00000094631 ENSG00000284774 ENSG00000165280 PMC8584317__F1 Progress of Signaling Pathways, Stress Pathways and Epigenetics in the Pathogenesis of Skeletal Fluorosis ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000168036 PMC2724661__F1 Complement system in AD ENSG00000113600 PMC8584317__F4 Progress of Signaling Pathways, Stress Pathways and Epigenetics in the Pathogenesis of Skeletal Fluorosis ENSG00000164690 ENSG00000128602 ENSG00000163501 PMC8960266__F1 Imaging Sub-Cellular Methionine and Insulin Interplay in Triple Negative Breast Cancer Lipid Droplet Metabolism PMC8623546__F11 Nephronophthisis-Pathobiology and Molecular Pathogenesis of a Rare Kidney Genetic Disease ENSG00000175054 ENSG00000164053 ENSG00000160602 ENSG00000051180 PMC8301100__F1 Contribution of the Nrf2 Pathway on Oxidative Damage and Mitochondrial Failure in Parkinson and Alzheimer’s Disease ENSG00000181019 ENSG00000100387 ENSG00000158828 ENSG00000079999 PMC4503872__F3 Results from a transcriptomic analysis of the OCM: Downregulated genes were, dependening on their level colored in green, upregulated in red ENSG00000284320 ENSG00000228716 ENSG00000100714 ENSG00000116984 PMC8301100__F2 Contribution of the Nrf2 Pathway on Oxidative Damage and Mitochondrial Failure in Parkinson and Alzheimer’s Disease ENSG00000010810 ENSG00000158828 PMC8623546__F10 Nephronophthisis-Pathobiology and Molecular Pathogenesis of a Rare Kidney Genetic Disease ENSG00000213658 ENSG00000163914 ENSG00000086730 PMC12071115__F2 Relationship between the regulation of TFPI2 expression in cancer cells and host cells ENSG00000019991 ENSG00000071655 ENSG00000138798 ENSG00000137648 ENSG00000197746 ENSG00000100345 ENSG00000130402 ENSG00000150455 PMC10882314__F2 Emerging role of SENP1 in tumorigenesis and cancer therapy ENSG00000102145 ENSG00000079387 ENSG00000087245 ENSG00000077152 ENSG00000136997 ENSG00000100985 ENSG00000142082 ENSG00000077782 ENSG00000168610 ENSG00000165819 ENSG00000159399 PMC4824625__F3 A-to-I editing of coding and non-coding RNAs by ADARs ENSG00000101945 ENSG00000173818 ENSG00000088888 ENSG00000160710 PMC7926383__F6 Genes of the VEGF-C/VEGFR-3 signaling pathway known to be involved in hereditary lymphedema ENSG00000140564 ENSG00000037280 ENSG00000122194 ENSG00000150630 PMC4824625__F4 A-to-I editing of coding and non-coding RNAs by ADARs ENSG00000160710 ENSG00000113360 PMC4495933__F3 Secreted Frizzled-related proteins (sFrps) ENSG00000154342 ENSG00000168487 PMC8357839__F6 Ketogenesis controls mitochondrial gene expression and rescues mitochondrial bioenergetics after cervical spinal cord injury in rats ENSG00000172005 ENSG00000168610 ENSG00000079999 PMC4495933__F2 Roles of Wnt/Beta-catenin signaling during vertebrate heart development ENSG00000166823 ENSG00000168036 PMC3104011__F2 miRNAs regulate DSB DDR through modulating the core protein components of various pathways ENSG00000012048 ENSG00000175054 ENSG00000163961 ENSG00000182185 ENSG00000108384 ENSG00000123374 ENSG00000051180 ENSG00000166851 ENSG00000139618 ENSG00000026103 PMC8416736__F2 Targeting non-coding RNAs in unstable atherosclerotic plaques: Mechanism, regulation, possibilities, and limitations ENSG00000125538 ENSG00000162692 ENSG00000137845 PMC6051890__F32 The diphthamide biosynthetic pathway and the mechanism of diphtheria toxicity ENSG00000154813 ENSG00000108963 PMC7155771__F2 The amino acid modulator arm of the mammalian target of rapamycin (mTOR) pathway ENSG00000177058 ENSG00000198793 ENSG00000145979 PMC4403556__F1 miR-137 Intersection Target Network of Neurological Disease ENSG00000157404 ENSG00000070831 ENSG00000148400 ENSG00000291971 ENSG00000166886 ENSG00000073756 ENSG00000136826 ENSG00000196136 ENSG00000100473 ENSG00000197860 ENSG00000114349 ENSG00000138166 ENSG00000137203 ENSG00000197386 ENSG00000053254 ENSG00000123374 ENSG00000134046 ENSG00000139687 ENSG00000277401 ENSG00000196712 PMC7729087__F4 Aminoacyl-tRNA synthetases and potential therapeutic applications ENSG00000178860 ENSG00000113361 ENSG00000106305 ENSG00000026103 PMC3344687__F7 Schematic diagram of the Heme/TLR4/MyD88 and/or TRIF hypothesis in ICH ENSG00000172936 ENSG00000136869 PMC4403556__F2 miR-137 targets within Protein Kinase A (PKA) Signaling Pathway ENSG00000106571 ENSG00000002330 ENSG00000107669 ENSG00000105246 ENSG00000128602 ENSG00000073756 ENSG00000196628 ENSG00000064300 PMC2972700__F1 Wnt Signaling During Fracture Repair ENSG00000138795 ENSG00000169071 ENSG00000162337 ENSG00000291971 ENSG00000134982 ENSG00000168036 ENSG00000104332 PMC5426069__F6 Analogue signalling pathway of TXNIP mediated by ER stress may be a novel therapeutic target in SAH-related EBI ENSG00000162711 ENSG00000144895 ENSG00000169136 ENSG00000265972 PMC3502657__F2 Signaling pathways for longevity ENSG00000129347 ENSG00000113649 PMC8713066__F1 Gut microbiota and probiotics on Alzheimer’s disease ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC3502657__F1 Signaling pathways for longevity ENSG00000118515 ENSG00000164327 PMC8861075__F1 Kynurenine Pathway Metabolites as Potential Clinical Biomarkers in Coronary Artery Disease ENSG00000188676 PMC12250041__F1 Experimental Models and Their Applicability in Inflammation Studies: Rodents, Fish, and Nematodes ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC5470738__F1 Novel Lipoprotein(a) Catabolism Pathway via Apolipoprotein(a) Recycling: Adding the Plasminogen Receptor PlgRKT to the List ENSG00000130164 ENSG00000107020 ENSG00000291836 ENSG00000198670 PMC11040350__F1 Platelet Membrane Nanocarriers Cascade Targeting Delivery System to Improve Myocardial Remodeling Post Myocardial Ischemia–Reperfusion Injury ENSG00000118520 ENSG00000168610 ENSG00000142224 PMC8629847__F1 MyD88 Signaling Leads to Cell Specific Functions in Cardiovascular Disease ENSG00000125538 ENSG00000134070 ENSG00000189403 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC12071115__F5 TFPI2 in pregnancy-induced hypertension, diabetes, and atherosclerosis ENSG00000108799 PMC6299090__F7 miR-100 maintains phenotype of tumor-associated macrophages by targeting mTOR to promote tumor metastasis via Stat5a/IL-1ra pathway in mouse breast cancer ENSG00000106571 ENSG00000198793 PMC3501616__F4 Expression and mutation analyses implicate ARHGAP29 as the etiologic gene for the cleft lip with or without cleft palate locus identified by genome wide association on chromosome 1p22 ENSG00000137203 PMC9626853__F1 Complement-targeting therapeutics for ischemia-reperfusion injury in transplantation and the potential for ex vivo delivery ENSG00000039537 ENSG00000291559 ENSG00000244731 ENSG00000166278 ENSG00000182326 ENSG00000236625 PMC6653007__F1 Ferroptosis induction ENSG00000168003 ENSG00000167107 ENSG00000128272 ENSG00000151012 ENSG00000167468 ENSG00000168610 ENSG00000062485 ENSG00000128965 PMC6524515__F1 ADAM17/TACE: a key molecule in brain injury regeneration ENSG00000163235 ENSG00000146648 PMC8992442__F2 Targeting of PI3K/AKT signaling and DNA damage response in acute myeloid leukemia: a novel therapeutic strategy to boost chemotherapy response and overcome resistance ENSG00000149311 ENSG00000171456 PMC6602878__F3 GDNF expression in Sertoli cells ENSG00000168214 ENSG00000148400 ENSG00000074181 ENSG00000184916 PMC7324848__F10 P-TEFb complex activation following activation of the A1-AR or ETR ENSG00000136807 ENSG00000141867 ENSG00000072364 PMC7226606__F1 Metabolic reprogramming in cancer cells ENSG00000131473 ENSG00000074800 ENSG00000291971 ENSG00000138798 ENSG00000142082 PMC9106060__F4 Determination of WWOX Function in Modulating Cellular Pathways Activated by AP-2A and AP-2G Transcription Factors in Bladder Cancer ENSG00000008710 ENSG00000159224 ENSG00000113456 ENSG00000213658 ENSG00000070831 ENSG00000163914 ENSG00000171540 ENSG00000084774 ENSG00000026103 PMC4845654__F4 Beyond Beta-catenin: prospects for a larger catenin network in the nucleus ENSG00000084093 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8548824__F3 Cabozantinib for HCC Treatment, From Clinical Back to Experimental Models ENSG00000122025 ENSG00000167601 ENSG00000198793 PMC10969083__F6 Low-Salt Diet Regulates the Metabolic and Signal Transduction Genomic Fabrics, and Remodels the Cardiac Normal and Chronic Pathological Pathways ENSG00000221914 ENSG00000050748 ENSG00000149782 ENSG00000121879 ENSG00000156475 ENSG00000168398 ENSG00000064012 ENSG00000101333 ENSG00000026103 ENSG00000104365 ENSG00000159128 ENSG00000198851 ENSG00000269335 ENSG00000173039 ENSG00000127955 ENSG00000027697 ENSG00000065559 ENSG00000060558 ENSG00000213341 ENSG00000168040 ENSG00000087460 ENSG00000007171 ENSG00000065135 ENSG00000117020 ENSG00000111537 ENSG00000177606 ENSG00000172936 ENSG00000175104 PMC10969083__F7 Low-Salt Diet Regulates the Metabolic and Signal Transduction Genomic Fabrics, and Remodels the Cardiac Normal and Chronic Pathological Pathways ENSG00000143158 ENSG00000067992 ENSG00000073578 ENSG00000131495 ENSG00000117118 ENSG00000156885 ENSG00000166136 ENSG00000147123 ENSG00000157184 ENSG00000139180 ENSG00000128609 ENSG00000110717 ENSG00000147684 ENSG00000184983 ENSG00000005882 ENSG00000126267 ENSG00000292058 ENSG00000165264 ENSG00000267855 ENSG00000108179 ENSG00000136521 ENSG00000127184 ENSG00000109390 ENSG00000131174 ENSG00000116459 ENSG00000213619 ENSG00000065518 ENSG00000151366 ENSG00000186010 ENSG00000189043 ENSG00000099795 ENSG00000119013 ENSG00000060762 ENSG00000160471 PMC8426249__F1 Increased presence of nuclear DNAJA3 and upregulation of cytosolic STAT1 and of nucleic acid sensors trigger innate immunity in the ClpP-null mouse ENSG00000171855 ENSG00000187608 ENSG00000115267 ENSG00000185745 ENSG00000276561 ENSG00000142166 ENSG00000150782 ENSG00000183735 ENSG00000117226 ENSG00000164430 ENSG00000088888 ENSG00000115415 ENSG00000125538 ENSG00000125656 PMC10969083__F4 Regulated genes in the Adrenergic signaling in cardiomyocyte KEGG-constructed pathway ENSG00000073711 ENSG00000221914 ENSG00000171791 ENSG00000156475 ENSG00000092054 ENSG00000157087 ENSG00000066027 ENSG00000007402 ENSG00000101333 ENSG00000112276 ENSG00000070961 ENSG00000178363 ENSG00000198626 ENSG00000143933 ENSG00000197616 ENSG00000137841 ENSG00000087460 ENSG00000068971 ENSG00000078304 ENSG00000118160 ENSG00000117020 ENSG00000128272 ENSG00000167535 ENSG00000112640 ENSG00000092020 ENSG00000100784 ENSG00000157445 ENSG00000121577 ENSG00000182389 PMC10969083__F5 Low-Salt Diet Regulates the Metabolic and Signal Transduction Genomic Fabrics, and Remodels the Cardiac Normal and Chronic Pathological Pathways ENSG00000142408 ENSG00000160789 ENSG00000196296 ENSG00000143549 ENSG00000166862 ENSG00000198626 ENSG00000197616 ENSG00000043591 ENSG00000087460 ENSG00000140416 ENSG00000118160 ENSG00000092054 ENSG00000167535 ENSG00000102119 ENSG00000157445 ENSG00000155657 ENSG00000182389 ENSG00000198947 PMC2173020__F1 Cross-talk between growth factors and integrins in endothelial cells ENSG00000291971 PMC4671844__F1 Molecular pathways leading to CRC ENSG00000157764 ENSG00000134982 ENSG00000095002 ENSG00000122512 PMC4671844__F2 MAPK signaling pathway in CRC ENSG00000198793 ENSG00000146648 PMC6292222__F3 T cell differentiation ENSG00000100385 ENSG00000134982 ENSG00000126353 PMC4428545__F2 Ratio heatmaps of identified canonical TCR signaling proteins that showed significant changes of phosphopeptide abundance for both types of stimulation (q value < 0.05; > 2–fold or < 0.5-fold) ENSG00000113263 PMC8261186__F3 Vitamin D Toxicity Managed with Peritoneal Dialysis ENSG00000111012 ENSG00000118972 ENSG00000152266 ENSG00000019186 ENSG00000186104 PMC3228973__F4 Proposed signal transduction pathways in nodose ganglia following receptor activation with leptin and cholecystokinin-8 (CCK-8) ENSG00000291971 ENSG00000163394 PMC5019079__F3 Hypothetical scheme of production and effects of oxidized fatty acids ENSG00000171759 PMC6538889__F1 Switch-on and switch-off of canonical and noncanonical Wnt signal pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000177606 ENSG00000168036 PMC8639147__F10 Mechanistic model of REST-dependent homeostatic rearrangement of inhibitory inputs in response to hyperactivity ENSG00000084093 ENSG00000174576 ENSG00000101438 PMC2938150__F3 Comparison of fluxes of central carbon metabolism determined by MFA and predicted from a genome-scale metabolic model ENSG00000167900 ENSG00000062485 PMC8136750__F2 NAD Metabolism and its biological role in mammalian cells ENSG00000105835 ENSG00000123572 PMC4399270__F4 Functions of Klotho ENSG00000111012 ENSG00000196839 ENSG00000150907 ENSG00000184481 PMC7645048__F7 LINC02381 effect on Wnt signaling pathway ENSG00000134982 ENSG00000168036 PMC3004524__F4 Model of pri-miRNA processing and localization ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC4870071__F1 Hepatocyte growth factor/mesenchymal epithelial transition factor and phosphoinositide 3-kinase/Akt/mammalian target of rapamycin pathway, and their inhibitors evaluated in gastric cancer patients ENSG00000019991 ENSG00000198793 PMC3094203__F3 Peroxisome proliferator-activated receptor G (PPARG) is a ligand-activated nuclear receptor with potent anti-inflammatory properties that modulates the immune inflammatory response ENSG00000177575 ENSG00000135218 ENSG00000113520 PMC8037155__F2 Leptin signaling pathway ENSG00000198793 ENSG00000173599 ENSG00000168610 PMC3329985__F4 Top Networks Associated With MK-801 Treatment Identified by Ingenuity Pathway Analysis ENSG00000100749 ENSG00000073578 ENSG00000175793 ENSG00000136997 ENSG00000197386 ENSG00000132639 PMC12030371__F1 Penoxsulam’s Effect on Chlorophyll Synthesis and the Metabolism of Foxtail Millet ENSG00000144410 ENSG00000126088 ENSG00000188690 ENSG00000127948 PMC3369606__F2 Role of DCs in the pathogenesis of GVHD ENSG00000125538 ENSG00000162692 ENSG00000026103 PMC9069066__F5 Differential Physiological, Transcriptomic, and Metabolomic Responses of Paspalum wettsteinii Under High-Temperature Stress ENSG00000117118 ENSG00000140464 PMC5482322__F1 The Plasticity of Cancer Cell Invasion ENSG00000145020 PMC5216695__F7 Beta-cell insulin receptor deficiency during in utero development induces an islet compensatory overgrowth response ENSG00000112715 ENSG00000140443 PMC4132766__F1 Metabolic pathways for PA production ENSG00000042832 ENSG00000198793 ENSG00000173599 ENSG00000198670 PMC12119316__F3 CHMs and natural compounds suppress the progression of AS by inhibiting the activation of NLRP3 inflammasome ENSG00000162711 ENSG00000172936 ENSG00000077463 ENSG00000096717 ENSG00000142082 PMC2856676__F1 Comparative Genomics of Flowering Time Pathways Using Brachypodium distachyon as a Model for the Temperate Grasses ENSG00000163435 ENSG00000102034 ENSG00000163933 ENSG00000100842 ENSG00000179632 ENSG00000203783 ENSG00000186654 ENSG00000125968 ENSG00000131188 ENSG00000135097 PMC7828702__F11 TGF-Beta-related oxidative stress signaling pathway in HTMCs (created in BioRender.com) PMC7246985__F6 Proposed model of Amuc_1434* effects on LS174T cells PMC8810793__F8 Overall schematic diagram ENSG00000188486 ENSG00000149311 ENSG00000131503 ENSG00000134057 PMC9653766__F1 Predictive and Prognostic Role of RAS–RAF–MEK–ERK Pathway Alterations in Breast Cancer: Revision of the Literature and Comparison with the Analysis of Cancer Genomic Datasets ENSG00000105722 ENSG00000120875 ENSG00000111344 ENSG00000115904 ENSG00000175592 ENSG00000141068 ENSG00000155903 ENSG00000169032 ENSG00000179295 ENSG00000157557 ENSG00000107263 ENSG00000136997 ENSG00000109756 ENSG00000187678 ENSG00000158050 ENSG00000136158 ENSG00000108861 ENSG00000152689 ENSG00000281877 ENSG00000116237 ENSG00000127445 ENSG00000171777 ENSG00000177189 ENSG00000105122 ENSG00000164050 ENSG00000164056 ENSG00000138166 ENSG00000171435 ENSG00000177606 ENSG00000280477 PMC3725129__F1 Proposed BP metabolic pathways and their representative metabolites ENSG00000163930 ENSG00000198610 ENSG00000187134 PMC9708800__F4 Targeting inflammasome-dependent mechanisms as an emerging pharmacological approach for osteoarthritis therapy ENSG00000278718 ENSG00000162711 ENSG00000150782 ENSG00000125538 ENSG00000086991 ENSG00000172936 ENSG00000096717 ENSG00000175104 ENSG00000184216 PMC6160134__F2 TGFB signaling and apoptosis ENSG00000137834 ENSG00000153094 ENSG00000095015 ENSG00000099860 ENSG00000171791 ENSG00000112715 ENSG00000100485 ENSG00000164305 ENSG00000276561 ENSG00000183735 ENSG00000136997 ENSG00000175104 ENSG00000064012 ENSG00000130513 ENSG00000158050 PMC4147234__F1 Infectious tolerance that depends on a nutrient depleted microenvironment maintained by Treg cells within tissues ENSG00000060982 ENSG00000129167 ENSG00000198793 ENSG00000140287 ENSG00000118520 ENSG00000049768 PMC4147234__F2 MTOR pathway in T cells ENSG00000164327 ENSG00000049768 PMC7886103__F9 Mechanism for protection of MgIG against ATO-treated cardiotoxicity ENSG00000136869 PMC7739562__F7 Diminished canonical Beta-catenin signaling during osteoblast differentiation contributes to osteopenia in progeria ENSG00000138795 ENSG00000134982 ENSG00000168036 PMC3880276__F9 Rapamycin Ameliorates Inflammation and Fibrosis in the Early Phase of Cirrhotic Portal Hypertension in Rats through Inhibition of mTORC1 but Not mTORC2 ENSG00000155792 ENSG00000186654 PMC5943138__F2 Control of B-1a cell development by instructive BCR signaling PMC7557502__F1 Neuregulins: protective and reparative growth factors in multiple forms of cardiovascular disease ENSG00000291971 ENSG00000198793 ENSG00000178568 PMC8965007__F5 Cross-Talks Among Bone Morphogenetic Protein (BMP) Signaling and Other Prominent Pathways Involved in Neural Differentiation ENSG00000170365 ENSG00000164690 ENSG00000128602 PMC8965007__F6 Cross-Talks Among Bone Morphogenetic Protein (BMP) Signaling and Other Prominent Pathways Involved in Neural Differentiation ENSG00000170365 ENSG00000134982 ENSG00000168036 PMC7564605__F1 IGF-1 signaling pathways ENSG00000177169 ENSG00000170365 ENSG00000169047 ENSG00000168036 ENSG00000140443 PMC9273796__F1 In silico structural and functional characterization of Antheraea mylitta cocoonase ENSG00000196531 ENSG00000141086 ENSG00000086730 PMC4919052__F10 Impact of Intramammary Escherichia coli Challenge on Liver and Mammary Transcriptome and Cross-Talk in Dairy Cows during Early Lactation Using RNAseq ENSG00000171855 ENSG00000128016 ENSG00000105329 ENSG00000122877 ENSG00000129514 ENSG00000009709 ENSG00000103490 ENSG00000172216 ENSG00000066336 ENSG00000150907 ENSG00000125538 ENSG00000189403 ENSG00000185591 ENSG00000100219 ENSG00000162892 ENSG00000113525 ENSG00000130513 ENSG00000116044 ENSG00000109320 ENSG00000173039 ENSG00000221869 ENSG00000162924 ENSG00000125347 ENSG00000168610 ENSG00000108691 ENSG00000111537 ENSG00000115415 ENSG00000177606 ENSG00000127616 PMC8785230__F1 ERRG, a new player in the type I IFN arena ENSG00000276561 ENSG00000142166 PMC6310611__F2 Metabolomics reveals the limitations for the in vivo application of GNF-351 due to poor absorption and high metabolism ENSG00000180210 ENSG00000117525 ENSG00000198734 ENSG00000140465 ENSG00000106546 PMC4452148__F2 Notch signaling pathway ENSG00000148400 ENSG00000074181 ENSG00000136997 ENSG00000133961 PMC2872207__F4 Akt signaling pathway ENSG00000198793 ENSG00000164327 PMC4452148__F3 Wnt/Beta-catenin signaling pathway ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000167074 PMC6372678__F6 Mitochondrial superoxide dismutase 2 mediates Gamma-irradiation-induced cancer cell invasion ENSG00000291971 ENSG00000168036 ENSG00000196562 ENSG00000168610 PMC3256499__F2 VEGF pathway and site of action of the inhibitors ENSG00000112715 ENSG00000150630 PMC6545365__F1 Schematic Representation of the Biogenesis and Secretion of ExosomesExosomes are formed as intraluminal vesicles (ILVs) ENSG00000041353 PMC4089153__F1 Sooner and later ENSG00000189403 ENSG00000145777 ENSG00000166090 PMC6682688__F5 ErbB/PI3K pathway regulation by miR-326 ENSG00000117020 ENSG00000002330 ENSG00000065361 ENSG00000198793 ENSG00000136997 ENSG00000112715 ENSG00000118971 PMC6406032__F2 Scheme summarizing the role of TRP channels in cardiac fibrosis ENSG00000187688 ENSG00000092439 ENSG00000133107 ENSG00000144935 ENSG00000137672 ENSG00000138741 ENSG00000196689 ENSG00000119121 PMC8416736__F3 Targeting non-coding RNAs in unstable atherosclerotic plaques: Mechanism, regulation, possibilities, and limitations ENSG00000108691 ENSG00000125538 ENSG00000168040 ENSG00000077463 ENSG00000136826 ENSG00000026103 PMC8416736__F4 Targeting non-coding RNAs in unstable atherosclerotic plaques: Mechanism, regulation, possibilities, and limitations ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC9595130__F3 Ferroptosis and musculoskeletal diseases: “Iron Maiden” cell death may be a promising therapeutic target ENSG00000168003 ENSG00000163930 ENSG00000151012 ENSG00000076554 ENSG00000167468 ENSG00000167996 ENSG00000111684 ENSG00000162772 ENSG00000142082 ENSG00000127948 ENSG00000123983 PMC5996875__F4 Fibroblast growth factor receptors and genes that are involved in FGF pathway were analyzed by IPA in KC iPSC compared with normal iPSC ENSG00000162889 ENSG00000019991 ENSG00000124181 ENSG00000077782 ENSG00000168610 PMC4637293__F1 Anticancer immune response of anti-PD-1/PD-L1 and the genetic determinants of response to anti-PD-1/PD-L1 antibodies in cancer patients ENSG00000156127 ENSG00000150907 ENSG00000198793 ENSG00000168610 PMC2872207__F1 TNF-induced NFKB pathway ENSG00000102871 PMC6350302__F5 Proposed model of PI3K activation in CM-RES clones ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC2860895__F1 TOM1L2 and genes associated with Alzheimer's disease in the human interactome ENSG00000142192 ENSG00000013016 ENSG00000174080 ENSG00000145147 ENSG00000136854 ENSG00000148842 ENSG00000175550 ENSG00000141485 ENSG00000154917 ENSG00000185236 ENSG00000132471 ENSG00000099889 ENSG00000143801 ENSG00000175662 ENSG00000117758 ENSG00000164756 ENSG00000140859 ENSG00000135519 ENSG00000024422 ENSG00000126432 ENSG00000005469 PMC2872207__F3 Jak/STAT signaling pathway ENSG00000128342 PMC7946999__F3 Different redox state between naïve CD4+ T cell and synovium in rheumatoid arthritis PMC3507479__F1 An expanded role of the tumor suppressor TSC1 in T cell tolerance ENSG00000122877 ENSG00000124181 PMC10144535__F7 Classical MAPK signaling pathway altered by 15 μM 7KCh treatment in mRPE cells and reversion effect exerted by 10 μM SA over this modulation ENSG00000117400 PMC10902464__F1 Galactose metabolism and CG pathophysiology PMC7566900__F2 BMAs-derived adipocytokines regulate behavior of metastatic breast cancer cells in the bone marrow ENSG00000174600 ENSG00000136869 PMC11977057__F6 Mechanism by which phanginin A activated SIK1 to promote glucose uptake in skeletal muscle ENSG00000142178 ENSG00000061273 ENSG00000108840 PMC7796379__F2 Scheme of the mechanisms underlying chemotherapy-induced peripheral neuropathy (CIPN) in mice treated with paclitaxel (A) or oxaliplatin (B) ENSG00000107562 ENSG00000134982 ENSG00000173599 ENSG00000189403 ENSG00000136869 ENSG00000121966 PMC7433558__F4 IVF-ET对胎盘绒毛FAK信号通路基因表达的影响Effect of IVF-ET on gene expression of FAK signaling pathway in placental villi ENSG00000002330 ENSG00000157764 ENSG00000070831 ENSG00000291971 ENSG00000168036 ENSG00000171791 PMC8065725__F6 Wnt/Beta-catenin signaling pathway in chronic HCV infection and HCV clearance without (A) or with (B) metformin treatment ENSG00000136997 ENSG00000168036 PMC8867697__F1 Inflammation and Cardiovascular Disease Associated With Hemodialysis for End-Stage Renal Disease ENSG00000062485 PMC4814460__F1 Autism spectrum disorders (ASD) candidate genes cluster into functional networks, and the two most prominent are synapse structure/function and protein translational control ENSG00000198793 ENSG00000173406 PMC11148314__F4 Emerging Perspectives of YAP/TAZ in Human Skin Epidermal and Dermal Aging ENSG00000164430 ENSG00000138071 PMC2805399__F8 A proposed working model of the complex Sertoli cell-germ cell interaction describing the mechanism by which Sertoli cells trigger germ cell apoptosis following MEHP-induced Sertoli cell injury ENSG00000087245 ENSG00000109320 ENSG00000185591 ENSG00000026103 PMC3236216__F5 Distinct Peripheral Blood RNA Responses to Salmonella in Pigs Differing in Salmonella Shedding Levels: Intersection of IFNG, TLR and miRNA Pathways ENSG00000101751 ENSG00000137033 ENSG00000163568 ENSG00000166169 ENSG00000276561 PMC10531892__F9 Thymoquinone, a Novel Multi-Strike Inhibitor of Pro-Tumorigenic Breast Cancer (BC) Markers: CALR, NLRP3 Pathway and sPD-L1 in PBMCs of HR+ and TNBC Patients ENSG00000162711 ENSG00000103490 PMC4563693__F7 Harnessing endogenous stem/progenitor cells for tendon regeneration ENSG00000041982 ENSG00000291748 ENSG00000260428 ENSG00000000005 PMC10531892__F8 Thymoquinone, a Novel Multi-Strike Inhibitor of Pro-Tumorigenic Breast Cancer (BC) Markers: CALR, NLRP3 Pathway and sPD-L1 in PBMCs of HR+ and TNBC Patients ENSG00000162711 ENSG00000103490 ENSG00000125538 ENSG00000040275 PMC4746415__F2 Expression of genes involved in the fibroblast growth factor (FGF) signaling pathway during goat pre-implantation development ENSG00000165556 ENSG00000285109 PMC10136283__F7 KEGG pathway map for Wnt signaling pathway ENSG00000087095 ENSG00000095739 ENSG00000100387 ENSG00000134982 ENSG00000167941 ENSG00000173156 ENSG00000148175 ENSG00000106483 ENSG00000196470 ENSG00000185269 PMC8218506__F4 Cornuside I promoted osteogenic differentiation of bone mesenchymal stem cells through PI3K/Akt signaling pathway ENSG00000123485 ENSG00000291964 ENSG00000262634 ENSG00000137807 ENSG00000138778 ENSG00000170775 ENSG00000089685 ENSG00000163734 ENSG00000169429 ENSG00000121621 ENSG00000131747 ENSG00000126787 ENSG00000117399 ENSG00000123219 ENSG00000117724 ENSG00000146670 ENSG00000117650 ENSG00000122952 ENSG00000156970 ENSG00000109805 ENSG00000280610 ENSG00000040275 ENSG00000112984 ENSG00000110200 ENSG00000170989 ENSG00000138180 ENSG00000151725 ENSG00000137804 ENSG00000197746 ENSG00000087586 ENSG00000124875 ENSG00000145386 ENSG00000144476 ENSG00000076382 ENSG00000180537 ENSG00000112742 ENSG00000108106 ENSG00000134690 ENSG00000007944 ENSG00000081041 ENSG00000277909 ENSG00000115163 ENSG00000184445 ENSG00000143228 ENSG00000138160 ENSG00000100162 ENSG00000198901 ENSG00000134057 ENSG00000171848 ENSG00000120334 PMC3709125__F1 Gene regulatory networks in mammalian sex determination ENSG00000162552 ENSG00000169218 ENSG00000104899 ENSG00000285109 ENSG00000146857 ENSG00000134363 ENSG00000096088 ENSG00000168036 ENSG00000102678 ENSG00000066468 ENSG00000173894 ENSG00000003137 ENSG00000125398 ENSG00000137090 ENSG00000005513 ENSG00000139549 ENSG00000054803 ENSG00000112299 PMC6776881__F1 Proposed working model of omega-3 PUFAs induced inhibitory effect on inflammation and autoimmunity ENSG00000138378 ENSG00000107485 PMC4710172__F2 Calcineurin-NFAT pathway: Activation and regulation ENSG00000285109 ENSG00000099991 ENSG00000127334 PMC4710172__F3 Promotion of cancer development and progression by NFAT ENSG00000099991 PMC4710172__F4 Inhibition of the calcineurin-NFAT pathway at multiple levels ENSG00000196388 PMC6357680__F9 Selected enriched KEGG pathways among DETs between S41 and S43 during tail resorption ENSG00000142192 ENSG00000168040 ENSG00000081051 PMC6557020__F2 Mechanisms of the SLIT/ROBO pathway as an oncogene in cancer ENSG00000145147 ENSG00000168036 ENSG00000154134 ENSG00000185008 PMC8249877__F1 Novel role of Hippo-Yap/TAZ signaling pathway in lymphatic vascular development ENSG00000126016 ENSG00000186575 ENSG00000291971 ENSG00000163914 ENSG00000131023 ENSG00000103335 ENSG00000150630 PMC8249877__F2 Novel role of Hippo-Yap/TAZ signaling pathway in lymphatic vascular development ENSG00000117707 ENSG00000150457 ENSG00000203883 ENSG00000131023 ENSG00000150630 PMC3853754__F1 The mitochondrial life cycle ENSG00000168958 ENSG00000116688 ENSG00000158828 ENSG00000171109 PMC9706587__F9 Development of functional nanomedicines for tumor associated macrophages-focused cancer immunotherapy ENSG00000182578 ENSG00000198053 PMC8096694__F1 Potential mechanisms by which Nrf2 signaling is regulated via protein interplay as a therapeutic process and in the pathogenesis of heart failure ENSG00000119682 ENSG00000167363 ENSG00000010810 ENSG00000077463 ENSG00000079999 PMC6832489__F1 Wnt/Beta-catenin signal transduction pathway in homeostasis ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000168646 PMC8096694__F2 Epigenetic regulations of Nrf2 signaling by noncoding RNAs in the pathogenesis of heart failure ENSG00000182809 ENSG00000077463 ENSG00000096717 ENSG00000156273 ENSG00000079999 PMC6832489__F2 Schematic view of sex determination ENSG00000162552 ENSG00000169218 ENSG00000104899 ENSG00000125398 ENSG00000168066 ENSG00000102678 PMC8096694__F3 MI-induced cardiac-derived EVs potentially regulate myocardial and brain Nrf2 signaling pathways by intra- and inter-organ communication ENSG00000119682 ENSG00000079999 PMC12209371__F1 Role and research progress of the MET signalling pathway in targeted therapy for osteosarcoma ENSG00000019991 ENSG00000198793 ENSG00000168036 ENSG00000183742 ENSG00000168610 PMC8385202__F3 Multi-functional roles of forkhead box protein O in skin aging and diseases ENSG00000148400 ENSG00000197632 ENSG00000115009 PMC11177995__F8 Schematic diagram for the mechanism underlying the apoVs-mediated rescue of the impaired OVX MSCs biological function and their capacity to improve osteoporosis ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC7338457__F8 PD-L1 promotes tumor growth and progression by activating WIP and Beta-catenin signaling pathways and predicts poor prognosis in lung cancer ENSG00000005882 ENSG00000198793 ENSG00000168036 PMC8249877__F3 Novel role of Hippo-Yap/TAZ signaling pathway in lymphatic vascular development ENSG00000176692 ENSG00000293604 ENSG00000117707 ENSG00000103335 ENSG00000150630 PMC4835216__F6 Prostaglandin-mediated inhibition of PTH-stimulated Beta-catenin signaling in osteoblasts by bone marrow macrophages ENSG00000152266 ENSG00000168036 PMC6661542__F2 Mechanisms involved in the regulation of glycometabolism in T2DM by RC ENSG00000138207 ENSG00000159224 ENSG00000171105 ENSG00000169047 ENSG00000175567 PMC4076815__F1 Typical PDA cell is depicted showing schematics of representative metabolic pathways that are altered in the disease in response to oncogenic Kras ENSG00000125166 ENSG00000065833 ENSG00000197713 ENSG00000198380 ENSG00000153574 ENSG00000115419 ENSG00000159399 PMC11491146__F7 Molecular mechanisms by which CCN2 regulates the activity of TRPV4 channels under mechanical stimulation in fibrochondrocytes ENSG00000125398 PMC10417430__F8 Synergistic effect of N3a with HSPs and mTOR inhibitors in lymphoma cells: Summary of the therapeutic scheme followed in our study, with major findings highlighted in bold ENSG00000198793 PMC8178367__F5 Microarray analysis reveals ONC201 mediated differential mechanisms of CHOP gene regulation in metastatic and nonmetastatic colorectal cancer cells ENSG00000291983 ENSG00000142192 ENSG00000128272 ENSG00000171791 ENSG00000127191 ENSG00000127948 PMC5927454__F15 Amelioration of CCl4 induced liver injury in swiss albino mice by antioxidant rich leaf extract of Croton bonplandianus Baill ENSG00000130649 PMC3871217__F12 Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways ENSG00000147162 ENSG00000150093 ENSG00000146648 PMC10417430__F4 Interruption of p53-MDM2 Interaction by Nutlin-3a in Human Lymphoma Cell Models Initiates a Cell-Dependent Global Effect on Transcriptome and Proteome Level ENSG00000112576 ENSG00000198793 ENSG00000134308 ENSG00000105647 ENSG00000164305 ENSG00000285069 ENSG00000080546 ENSG00000137801 ENSG00000171720 ENSG00000120868 ENSG00000116030 ENSG00000146007 ENSG00000188612 ENSG00000139687 ENSG00000140464 ENSG00000253729 ENSG00000026103 ENSG00000155827 ENSG00000170027 ENSG00000085117 ENSG00000175793 ENSG00000157106 ENSG00000127191 ENSG00000172667 ENSG00000168564 ENSG00000134574 ENSG00000134057 ENSG00000135446 ENSG00000171848 ENSG00000103460 ENSG00000092203 ENSG00000112378 ENSG00000075218 ENSG00000149554 ENSG00000171608 ENSG00000096717 ENSG00000127616 ENSG00000175305 ENSG00000149480 ENSG00000108312 PMC8616169__F4 Oncogenic KRAS: Signaling and Drug Resistance ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8074531__F1 Simplified model of insulin-stimulated translocation of the GLUT4 glucose transporter in skeletal muscle ENSG00000149269 ENSG00000169047 ENSG00000220205 PMC2752022__F2 FoxO factors in endothelial cells ENSG00000162692 PMC2752022__F3 Akt-FoxO pathway in regulation of heart size ENSG00000042832 ENSG00000198793 PMC8560795__F2 Targeting Sphingolipids for Cancer Therapy ENSG00000118785 ENSG00000102172 PMC11894248__F3 An example of the complexity of p21‐activated kinase (Pak1) signaling in a ventricular cardiac myocyte ENSG00000070831 ENSG00000149269 ENSG00000163914 PMC11894248__F4 Scheme illustrating ON and OFF states of the canonical Hippo signaling pathway ENSG00000114978 ENSG00000131023 ENSG00000291442 PMC8224699__F2 Recent Findings on Thymoquinone and Its Applications as a Nanocarrier for the Treatment of Cancer and Rheumatoid Arthritis ENSG00000163064 ENSG00000164778 PMC10451660__F3 AhR signaling pathway ENSG00000291971 ENSG00000106546 PMC6941088__F2 The classical and alternative nuclear factor-KB (NFKB) signaling pathways ENSG00000104856 ENSG00000125538 PMC6374618__F4 Schematic relationships between the wound-induced signal transduction mechanisms for the sesquiterpene biosynthesis and regulation in Aquilaria species for the agarwood production ENSG00000136997 ENSG00000197429 PMC11899273__F2 Schematic diagram of LPS clearance: LPS entering the systemic circulation binds to HDL in the blood to form an LPS–HDL complex ENSG00000172936 ENSG00000136869 ENSG00000162692 PMC2796930__F7 FGF-receptor signalling in the generation of hindbrain neural cell diversity ENSG00000125398 ENSG00000205927 ENSG00000164690 PMC11899273__F3 Increased expression of FABP4 in LSECs may represent a potential target for liver injury ENSG00000169245 ENSG00000186810 PMC8308051__F3 Reelin Alleviates Mesenchymal Stem Cell Senescence and Reduces Pathological Alpha-Synuclein Expression in an In Vitro Model of Parkinson’s Disease ENSG00000136457 ENSG00000135218 ENSG00000110799 ENSG00000026508 PMC3329512__F7 The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism ENSG00000173599 ENSG00000079432 ENSG00000026103 PMC3329512__F3 The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism ENSG00000196549 ENSG00000173599 PMC6478549__F1 An overview of major metabolic pathways in resting and activated fibroblasts ENSG00000180210 ENSG00000110711 ENSG00000092621 ENSG00000135069 ENSG00000146733 ENSG00000115419 PMC3329512__F4 The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism ENSG00000173599 ENSG00000079432 PMC4841705__F3 Regulation of Macrophage NO Production by H ENSG00000081181 ENSG00000003989 ENSG00000007171 PMC6165502__F1 The BMPR2 signaling pathway illustrating the potential canonical (green) and noncanonical (grey, blue) targets that can be activated ENSG00000170365 ENSG00000198742 ENSG00000283060 ENSG00000204217 ENSG00000125968 PMC3499814__F2 RIG-I signaling pathway and inhibition by influenza A viruses (Figure adapted from ) ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000175104 ENSG00000121060 PMC3499814__F3 Type I IFN signaling pathway and inhibition by influenza A viruses (Figure adapted from ) ENSG00000213928 ENSG00000187608 ENSG00000115415 ENSG00000276561 PMC4246236__F1 Cholesterol metabolism, lipid rafts and cellular prion propagation ENSG00000113161 ENSG00000141458 PMC8583941__F2 Deacetylation of Transcription Factors in Carcinogenesis ENSG00000145604 ENSG00000187531 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000283100 PMC7875488__F7 A HH/Gli-Foxf1-Wnt signaling network controlling Sox9+ chondrogenesis ENSG00000162552 ENSG00000125398 ENSG00000188064 ENSG00000103241 ENSG00000164690 ENSG00000185269 ENSG00000163501 PMC3737553__F6 Our proposed model for two distinct pathways in ICL-induced ATR signaling ENSG00000175054 ENSG00000164053 ENSG00000276618 PMC10874752__F13 miR-140-y targets TCF4 to regulate the Wnt signaling pathway and promote embryonic feather follicle development in Hungarian white goose ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC5702629__F5 Enriched canonical pathway for toll-like receptor signaling at 48 hps with dsRNA ENSG00000239732 ENSG00000144410 ENSG00000170458 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC4129529__F1 Cell-proliferative signaling pathways in lung cancer cell ENSG00000065361 ENSG00000146648 ENSG00000178568 PMC5410752__F1 Schema of the migratory modes of the excitatory neurons during neocortical development and molecular mechanisms downstream of Reelin signaling that control neuronal migration ENSG00000170558 PMC8313358__F2 Posttreatment Downregulation of Type III Interferons in Patients with Acute Brucellosis ENSG00000134982 ENSG00000110324 PMC7216002__F1 Heme biosynthesis pathway (left) and the principle of HAL mediated PpIX production enhancement with dimethylsulphoxide (DMSO) or deferoxamine mesylate salt (DFO) (right) ENSG00000144659 ENSG00000135776 ENSG00000066926 ENSG00000126088 ENSG00000256269 ENSG00000084110 ENSG00000188690 ENSG00000115657 ENSG00000118777 PMC4742122__F6 The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: new therapeutic targets ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC2593012__F2 Gene expression data mapped on the Mus musculus fatty acid synthesis pathway ENSG00000169710 PMC7730327__F2 TAp63A acts as the central integrator for DNA damage signaling in oocytes ENSG00000149311 ENSG00000175054 PMC2593012__F3 Gene expression data mapped on the mouse insulin signaling pathway ENSG00000177606 ENSG00000172005 ENSG00000078098 PMC9110800__F2 Genetic and Epigenetic Interplay Define Disease Onset and Severity in Repeat Diseases ENSG00000113318 ENSG00000145321 ENSG00000095002 ENSG00000102974 PMC3260921__F2 Integrin signalling pathway ENSG00000114209 PMC3825669__F3 KEGG “cell cycle” pathway relevant to NRF1 target genes ENSG00000039537 ENSG00000118007 ENSG00000108055 ENSG00000134982 ENSG00000205250 ENSG00000091651 ENSG00000277273 ENSG00000101224 ENSG00000117399 ENSG00000276876 ENSG00000145604 ENSG00000094804 ENSG00000101972 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000164754 PMC3825669__F4 KEGG “Parkinson’s disease” pathway relevant to NRF1 target genes ENSG00000132906 ENSG00000164305 ENSG00000174611 ENSG00000115317 PMC3825669__F6 IPA “regulation of eIF4 and p70S6K signaling” pathway relevant to NRF target genes ENSG00000163435 ENSG00000102034 ENSG00000169047 ENSG00000172239 PMC8481579__F5 Paeoniae Radix Alba in the Treatment of Non-alcoholic Fatty Liver Disease Based on Sequential Metabolites Identification Approach, Network Pharmacology, and Binding Affinity Measurement ENSG00000171105 ENSG00000169047 ENSG00000127191 PMC3383919__F1 Schematic model of the Hippo signaling cascade in mammals ENSG00000126016 ENSG00000109321 ENSG00000089685 ENSG00000132849 ENSG00000131023 PMC8381548__F1 Therapeutic strategies in METex14 skipping mutated non-small cell lung cancer ENSG00000019991 ENSG00000291971 ENSG00000168610 PMC1315902__F2 Multiple roles for kinases in DNA replication ENSG00000132646 ENSG00000166278 PMC6651423__F2 Mechanism of Activation for the Non-Canonical and Alternative NLRP3 Inflammasome Pathways ENSG00000162711 ENSG00000137275 ENSG00000172936 ENSG00000136869 ENSG00000168040 PMC3366472__F2 TLR-4 signaling in cancer ENSG00000170458 ENSG00000172005 ENSG00000189403 ENSG00000172936 ENSG00000150455 PMC3375870__F1 miR-23a, a critical regulator of “migR”ation and metastasis in colorectal cancer ENSG00000143878 ENSG00000291971 ENSG00000177606 ENSG00000136997 ENSG00000273529 ENSG00000109670 PMC8514722__F7 NFIL3 Facilitates Neutrophil Autophagy, Neutrophil Extracellular Trap Formation and Inflammation During Gout via REDD1-Dependent mTOR Inactivation ENSG00000165030 ENSG00000125538 ENSG00000198793 PMC3277529__F1 Proposed model for TIMP-1–mediated suppression of the Wnt/Beta-catenin pathway via let-7f in human mesenchymal stem cells (hMSCs) ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000135404 ENSG00000168646 PMC3032697__F15 Time course changes in cytokine network pathways of lungs from 9 V/null mice ENSG00000108702 ENSG00000177575 ENSG00000081181 ENSG00000117400 ENSG00000102996 PMC6709637__F9 Summary diagram ENSG00000105329 ENSG00000026508 PMC11766572__F1 MYD88 and IRAK signaling pathway ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC5099458__F1 Canonical and noncanonical Notch signaling pathways ENSG00000168036 ENSG00000079999 PMC5520166__F3 Regulatory role of ubiquitin on RIP1 and RIP3-dependent cell death ENSG00000173805 ENSG00000102871 ENSG00000083799 ENSG00000168404 PMC9325968__F2 Immunological Synapse: An Emerging Target for Immune Evasion by Bacterial Pathogens ENSG00000291603 ENSG00000213658 ENSG00000134982 PMC5427230__F1 The theophylline metabolic pathway ENSG00000140505 ENSG00000130649 PMC4374755__F7 Involvement of DNA-PKcs in the Type I IFN Response to CpG-ODNs in Conventional Dendritic Cells in TLR9-Dependent or -Independent Manners ENSG00000239732 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000175104 PMC4826884__F2 Immune signaling in C ENSG00000118515 PMC3654365__F5 Summary of the metabolic pathways in which the metabolites described in this paper are involved ENSG00000205221 ENSG00000122966 PMC6996089__F1 Bile acid synthesis pathways ENSG00000242110 ENSG00000276559 ENSG00000198610 ENSG00000036530 ENSG00000133835 ENSG00000180432 ENSG00000117528 ENSG00000099377 ENSG00000115271 ENSG00000083807 ENSG00000135929 PMC8202879__F7 LncRNAs induce oxidative stress and spermatogenesis by regulating endoplasmic reticulum genes and pathways ENSG00000211445 ENSG00000185591 ENSG00000140465 ENSG00000127948 ENSG00000158125 PMC11936574__F1 Interleukin-18 signaling pathway and its functional binding with IL-18 receptor ENSG00000162711 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000137496 PMC8052259__F1 m6A regulates innate immune signaling pathways ENSG00000183735 ENSG00000088888 ENSG00000198492 ENSG00000172936 ENSG00000136869 PMC4254984__F4 C-peptide-initiated signaling cascades ENSG00000169047 PMC8052259__F2 m6A regulates IFNB and the type I IFN response ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000149658 ENSG00000198492 ENSG00000142166 PMC8052259__F3 m6A regulates immune cell function ENSG00000149658 ENSG00000114737 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000105639 PMC6913124__F7 Putative role of miR-146a in CVB infection ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC3128433__F3 Complement cascade, hemolyisis, and eculizumab ENSG00000196352 PMC3562086__F1 Connecting the Insulin pathway to the Drosophila autophagy machinery ENSG00000152348 ENSG00000144848 ENSG00000164327 ENSG00000145782 ENSG00000057663 PMC9663387__F1 Optogenetic interrogation of cell signalling: human neuropsin (hOPN5) represents a potent tool for controlling the Gq pathway with light ENSG00000069482 ENSG00000137672 PMC5883378__F2 Two signaling pathways ENSG00000187554 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC4285539__F9 Signaling model for IP-10 production induced by MRP8/MRP14 ENSG00000183735 ENSG00000172936 ENSG00000136869 PMC9139286__F4 DEAD/H-Box Helicases in Immunity, Inflammation, Cell Differentiation, and Cell Death and Disease ENSG00000162711 ENSG00000168040 ENSG00000064012 ENSG00000215301 PMC8657588__F1 Toll-like Receptors (TLRs) Mediated Inflammation in Pancreatic Cancer Pathophysiology ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000115009 ENSG00000164342 PMC3597360__F4 Pathways leading to actin polymerization in the myogenic response ENSG00000070831 ENSG00000291971 PMC6717912__F1 Immune cell development and trafficking to the heart ENSG00000186810 ENSG00000081041 ENSG00000163739 ENSG00000125538 ENSG00000138755 ENSG00000105656 ENSG00000169429 ENSG00000162692 ENSG00000121807 PMC8516553__F5 Insights into the Role of Oxidative Stress in Ovarian Cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8600399__F8 MicroRNA-218-5p in sevoflurane-induced protective effects in hepatic ischemia/reperfusion injury mice by regulating GAB2/PI3K/AKT pathway ENSG00000033327 ENSG00000198793 PMC8323643__F1 Interleukin-10: A double-edged sword in breast cancer ENSG00000105397 ENSG00000110324 ENSG00000168610 PMC8019201__F3 Molecular mechanisms of the role of enhancer of zeste homolog 2 (EZH2) in a polycomb repressive complex 2 (PRC2)‐independent manner ENSG00000104856 ENSG00000285109 ENSG00000136997 ENSG00000173039 ENSG00000168036 ENSG00000105639 ENSG00000168610 ENSG00000069667 ENSG00000130726 PMC5860992__F1 Adapting Secretory Proteostasis and Function through the Unfolded Protein Response ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC6801718__F10 Summary of data showing TGFB1 recruitment of miR-143 and miR-145 to RISC to destabilize CFTR mRNA and impair the corrector/potentiator-mediated rescue of F508del-CFTR ENSG00000105329 ENSG00000001626 ENSG00000123908 PMC11816580__F1 In MASLD, CS affects the AMPK signaling pathway in different ways in the liver (A), adipose tissue (B), and ileum (C) to perturb lipid metabolism ENSG00000042832 ENSG00000169047 ENSG00000198793 ENSG00000005381 ENSG00000096717 ENSG00000079999 ENSG00000026103 PMC11816580__F2 Molecular mechanism of CS-induced hepatocellular damage ENSG00000278718 ENSG00000162711 ENSG00000065833 ENSG00000130649 ENSG00000171791 ENSG00000274768 ENSG00000168040 ENSG00000007171 ENSG00000026103 PMC11816580__F3 Downstream signaling in regard to the promotion of liver fibrosis by CS ENSG00000162552 ENSG00000004975 ENSG00000087245 ENSG00000291748 ENSG00000168036 ENSG00000108821 ENSG00000168610 ENSG00000062485 PMC7611882__F4 Non-canonical glutamine transamination sustains efferocytosis by coupling redox buffering to oxidative phosphorylation ENSG00000000419 ENSG00000100288 ENSG00000182197 ENSG00000159322 ENSG00000168803 ENSG00000077514 ENSG00000135069 ENSG00000163541 ENSG00000241878 ENSG00000104368 ENSG00000127884 ENSG00000101868 ENSG00000117054 ENSG00000003137 ENSG00000172292 ENSG00000100714 ENSG00000100412 ENSG00000291814 ENSG00000119523 ENSG00000188921 ENSG00000118520 ENSG00000109743 ENSG00000176597 ENSG00000084110 ENSG00000049860 ENSG00000058866 ENSG00000198363 ENSG00000143418 ENSG00000121897 ENSG00000137992 ENSG00000124357 ENSG00000188611 ENSG00000151498 ENSG00000068120 ENSG00000127948 ENSG00000084774 PMC5129526__F1 Transcriptional regulation of glucose metabolism during active TB disease and in PBMCs stimulated with Mtb ENSG00000151726 ENSG00000067992 ENSG00000073578 ENSG00000117118 ENSG00000169047 ENSG00000198793 ENSG00000163541 ENSG00000178685 ENSG00000150782 ENSG00000205138 ENSG00000146701 ENSG00000123983 ENSG00000062485 ENSG00000131473 ENSG00000108515 ENSG00000172340 ENSG00000101365 ENSG00000183648 ENSG00000109270 ENSG00000059378 ENSG00000197142 ENSG00000178467 ENSG00000159399 ENSG00000111224 ENSG00000152556 PMC4222074__F4 Network links between 23 genes in pathway of mismatch repair and three driver genes ENSG00000114125 ENSG00000099204 ENSG00000144749 ENSG00000113318 ENSG00000132383 ENSG00000168036 ENSG00000136153 ENSG00000077514 ENSG00000139263 ENSG00000064933 ENSG00000122512 PMC12141845__F1 Canonical Wnt signalling pathway with osteokine and pro-inflammatory marker inhibitors ENSG00000281324 ENSG00000162337 ENSG00000167941 PMC8550759__F8 RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy ENSG00000157764 ENSG00000169071 ENSG00000185483 ENSG00000108375 PMC9277259__F1 EMT in the DNA damage response, double‐strand break repair pathway choice and its implications in cancer treatment ENSG00000012061 ENSG00000143799 ENSG00000083093 ENSG00000128951 ENSG00000080345 ENSG00000253251 ENSG00000291803 ENSG00000171984 ENSG00000122376 ENSG00000310560 ENSG00000139618 ENSG00000112130 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000169621 ENSG00000144554 ENSG00000122691 ENSG00000197299 ENSG00000041880 ENSG00000051180 ENSG00000227345 PMC5888819__F1 Dysregulated genes and their associated microRNAs in the KEGG MAPK-signaling pathway in colorectal cancer ENSG00000087095 ENSG00000172680 ENSG00000158825 ENSG00000082212 ENSG00000026103 PMC1525228__F9 Diagram depicting the mechanism by which NGF may inhibit GSK-3B and promote axon growth PMC8096351__F8 Identification, Biological Activities and Biosynthetic Pathway of Dendrobium Alkaloids ENSG00000110921 ENSG00000100473 ENSG00000197429 ENSG00000167508 PMC3170890__F1 IL-10 signal transduction and hypothesized treatment by dual gene therapy ENSG00000168610 PMC5869528__F9 Toll-like receptor signaling pathway ENSG00000239732 ENSG00000144410 ENSG00000170458 ENSG00000136869 ENSG00000131323 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000164342 ENSG00000143387 PMC4169706__F2 Genome-wide association analysis of anti-TNF drug response in rheumatoid arthritis patients ENSG00000130037 ENSG00000039537 ENSG00000004864 ENSG00000169783 ENSG00000185532 ENSG00000197467 ENSG00000173406 ENSG00000069667 ENSG00000080644 PMC4701046__F2 Signaling pathways in melanoma ENSG00000002330 ENSG00000157764 ENSG00000070831 ENSG00000198793 ENSG00000196712 PMC4148370__F3 Differentially expressed genes (DEGs) in the T-cell receptor signaling pathway ENSG00000291603 ENSG00000110395 ENSG00000213658 ENSG00000010810 ENSG00000135446 ENSG00000113263 PMC4148370__F2 Differentially expressed genes (DEGs) in the B-cell receptor signaling pathway ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000110651 ENSG00000010671 PMC2854193__F1 Autophagy Genes as Tumor Suppressors ENSG00000110497 ENSG00000152348 ENSG00000123395 ENSG00000198382 ENSG00000198793 ENSG00000144848 ENSG00000145782 PMC11201619__F2 Targets to Search for New Pharmacological Treatment in Idiopathic Parkinson’s Disease According to the Single-Neuron Degeneration Model ENSG00000079999 PMC3759859__F2 Oncogenic role of the AKT signaling pathway ENSG00000002330 ENSG00000198793 ENSG00000164327 PMC3759859__F3 p53-induced cell cycle control and apoptosis ENSG00000149311 ENSG00000175054 PMC3759859__F4 Interplay between p53 and AKT/mTOR in regulating autophagy ENSG00000149311 ENSG00000175054 ENSG00000198793 PMC6102891__F7 Signaling pathway of OS and pregnancy (a brief view) ENSG00000079999 PMC9331760__F4 HDACs in the Response of Cancer Cells to Cellular Stress and the Potential for Therapeutic Intervention ENSG00000171720 ENSG00000178573 ENSG00000096717 ENSG00000156273 ENSG00000079999 PMC3359119__F1 mTORC1 signaling and regulation of pancreatic Beta-cell mass ENSG00000011566 ENSG00000006451 ENSG00000198793 ENSG00000169047 ENSG00000284161 ENSG00000155792 ENSG00000164327 PMC4403188__F6 GAi1/3-mediated activation of TLR4 in response to LPS ENSG00000170458 ENSG00000125538 ENSG00000173039 ENSG00000172936 ENSG00000136869 ENSG00000131323 PMC9213371__F1 NFKB in control of regulatory T cell development, identity, and function ENSG00000104856 ENSG00000173039 ENSG00000049768 ENSG00000185010 PMC7917472__F4 PI3K-Akt signaling pathway regulated by EZP ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000183979 ENSG00000198793 ENSG00000111816 PMC3612853__F1 Signaling and transcriptional regulation of Th17 polarization ENSG00000198793 ENSG00000103522 ENSG00000049768 ENSG00000168610 ENSG00000106546 ENSG00000069667 ENSG00000162594 ENSG00000138378 ENSG00000111537 ENSG00000159216 ENSG00000115415 ENSG00000156127 ENSG00000137265 ENSG00000107485 PMC10398793__F4 In the IPA data software the disease and function analysis of the RNA sequencing data from Primbio ENSG00000284774 ENSG00000101460 ENSG00000150907 ENSG00000198793 ENSG00000187837 ENSG00000136997 ENSG00000169429 ENSG00000188130 PMC6912474__F2 Organelle homeostasis imbalance signaling pathways ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000108788 PMC4848680__F4 Eicosanoid synthesis pathways: Arachidonic acid is a polyunsaturated fatty acid that is released from the cellular membranes by cytoplasmatic phospholipase A2 (PLA2) PMC3482945__F3 Pathway related to prostate cancer ENSG00000125834 ENSG00000066926 ENSG00000175793 ENSG00000044446 ENSG00000149091 ENSG00000285070 ENSG00000116649 ENSG00000169116 ENSG00000131844 PMC3696647__F7 Schematic diagram for HIF-1A functions in cap-dependent translation of selective mRNAs, cell proliferation, and tumorsphere growth of cancer cells in low O2 environment ENSG00000173933 ENSG00000198793 ENSG00000163412 PMC7162614__F6 Adding MASP1 to the lectin pathway—Leprosy association puzzle: Hints from gene polymorphisms and protein levels ENSG00000042832 ENSG00000203710 PMC12144611__F3 Decoding CD24: Roles of chemoradiotherapy resistance and potential as therapeutic targets ENSG00000272398 ENSG00000165527 ENSG00000168610 PMC8776696__F4 Transcriptomic profiling reveals gene expression in human peripheral blood after exposure to low-dose ionizing radiation ENSG00000122543 ENSG00000228278 ENSG00000100448 ENSG00000276051 ENSG00000232629 ENSG00000273686 ENSG00000111331 ENSG00000165264 PMC7661869__F1 ARHGAP24 inactivated Rac1/Akt/NFKB in acute pneumonia ENSG00000138639 ENSG00000125538 PMC9422807__F2 Comparing the Cytokine Storms of COVID-19 and Pandemic Influenza ENSG00000169245 ENSG00000138755 ENSG00000172005 ENSG00000026103 PMC3136090__F5 Signaling schematic representation: The postulated signaling pathway involved in this study ENSG00000166402 ENSG00000163914 ENSG00000123374 PMC7515907__F3 Interconnections between cilia, aging and Alzheimer’s disease genes ENSG00000140992 ENSG00000204104 ENSG00000008710 ENSG00000104450 ENSG00000092200 ENSG00000164327 ENSG00000120885 ENSG00000118997 ENSG00000171791 ENSG00000067369 ENSG00000114446 ENSG00000165506 ENSG00000138686 ENSG00000012048 ENSG00000108578 ENSG00000140463 ENSG00000109083 ENSG00000143801 ENSG00000187535 ENSG00000116133 ENSG00000100211 ENSG00000144061 ENSG00000139687 ENSG00000103266 ENSG00000168589 ENSG00000157212 ENSG00000132170 ENSG00000183395 ENSG00000155975 ENSG00000175899 ENSG00000147601 ENSG00000146648 ENSG00000291505 ENSG00000004838 ENSG00000165169 ENSG00000159625 ENSG00000185842 ENSG00000288174 ENSG00000112715 ENSG00000164305 ENSG00000149295 ENSG00000115317 ENSG00000102145 ENSG00000074800 ENSG00000132383 ENSG00000051180 ENSG00000119912 ENSG00000171105 ENSG00000119541 ENSG00000100906 ENSG00000074319 ENSG00000169379 ENSG00000250506 ENSG00000143933 ENSG00000170248 ENSG00000160691 ENSG00000120899 ENSG00000177606 ENSG00000164362 ENSG00000125124 ENSG00000128285 ENSG00000122970 PMC8956889__F2 Ileum transcriptional response to prolonged supplementation with phytogenic product containing menthol, carvacrol and carvone ENSG00000094804 ENSG00000167513 ENSG00000115942 ENSG00000135336 ENSG00000091651 ENSG00000093009 PMC4910530__F1 Lost & found: C9ORF72 and the autophagy pathway in ALS/FTD ENSG00000183735 ENSG00000106460 ENSG00000165280 ENSG00000147894 PMC5861487__F3 TGFB pathway ENSG00000049323 ENSG00000170365 ENSG00000137834 ENSG00000111537 ENSG00000095739 ENSG00000100387 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000185591 ENSG00000205250 ENSG00000137801 PMC2874810__F3 Ingenuity Pathway Analysis Network ENSG00000160888 ENSG00000125740 ENSG00000128016 ENSG00000105835 ENSG00000138670 ENSG00000106714 ENSG00000292288 ENSG00000138798 ENSG00000197746 ENSG00000122877 ENSG00000137699 ENSG00000121807 ENSG00000121966 ENSG00000076864 ENSG00000144802 ENSG00000125538 ENSG00000118515 ENSG00000179094 ENSG00000168263 ENSG00000158050 ENSG00000121552 ENSG00000106066 ENSG00000081041 ENSG00000090104 ENSG00000099985 ENSG00000100906 ENSG00000109321 ENSG00000101470 ENSG00000036828 ENSG00000073756 ENSG00000274665 ENSG00000124882 ENSG00000137575 ENSG00000288325 ENSG00000116218 ENSG00000141526 ENSG00000173334 PMC8307213__F6 Melatonin Treatment Improves Renal Fibrosis via miR-4516/SIAH3/PINK1 Axis ENSG00000215475 ENSG00000158828 ENSG00000171109 PMC4281589__F1 Retinoic acid (RA) synthesis pathway in the gut ENSG00000187554 PMC8493399__F8 Cyy260, a novel small molecule inhibitor, suppresses non-small cell lung cancer cell growth via JAK2/STAT3 pathway ENSG00000198793 ENSG00000168610 ENSG00000164305 PMC3246074__F2 Vitamin A and immune regulation: Role of retinoic acid in gut-associated dendritic cell education, immune protection and tolerance ENSG00000168036 ENSG00000172936 PMC6689321__F3 Cross-talk between the CDK4/6 and mitogenic signaling pathways in cancer ENSG00000135446 ENSG00000105810 PMC4288257__F5 Malonylated proteins in glucose and fatty acid metabolism pathways ENSG00000131473 ENSG00000151726 ENSG00000120437 ENSG00000102977 ENSG00000167107 ENSG00000173599 ENSG00000197142 ENSG00000100504 ENSG00000164708 ENSG00000075239 ENSG00000136872 ENSG00000113790 ENSG00000117305 ENSG00000026103 PMC7261485__F9 ATP11B deficiency leads to impairment of hippocampal synaptic plasticity ENSG00000198576 ENSG00000102003 ENSG00000132535 PMC7427992__F7 TG-resident HSV-specific memory CD8+ TRM cells downregulate the T cell exhaustion associated pathway and confer protection from ocular herpes in HSV-1 infected asymptomatic humans and HLA transgenic rabbits ENSG00000186810 ENSG00000089692 ENSG00000042832 ENSG00000181847 ENSG00000026508 ENSG00000126353 PMC5216743__F6 Expression of functional neuronal receptor latrophilin 1 in human acute myeloid leukaemia cells ENSG00000136869 ENSG00000010671 PMC3994729__F4 Expressional regulation of genes linked to immunity & programmed development in human early placental villi ENSG00000105397 ENSG00000185267 ENSG00000105639 ENSG00000168610 PMC7542157__F2 Molecular mechanisms of NADPH homeostasis in cancer ENSG00000228716 ENSG00000125166 ENSG00000151376 ENSG00000065833 ENSG00000065911 ENSG00000135423 ENSG00000100714 ENSG00000163738 ENSG00000112992 ENSG00000082212 PMC9710037__F2 Mathematical model of the cell signaling pathway based on the extended Boolean network model with a stochastic process ENSG00000146648 PMC4815038__F8 ATF4 induction through an atypical integrated stress response to ONC201 triggers p53-independent apoptosis in hematological malignancies ENSG00000168209 ENSG00000128272 ENSG00000171791 PMC7987945__F6 Transcriptome Analysis of Ovarian Follicles Reveals Potential Pivotal Genes Associated With Increased and Decreased Rates of Chicken Egg Production ENSG00000162975 ENSG00000145864 ENSG00000147684 ENSG00000198739 ENSG00000115392 ENSG00000149294 ENSG00000292058 ENSG00000180902 ENSG00000004779 ENSG00000153827 ENSG00000182256 ENSG00000135838 ENSG00000197265 ENSG00000102287 ENSG00000150672 ENSG00000213619 ENSG00000151366 ENSG00000113327 ENSG00000067191 ENSG00000154654 ENSG00000132535 ENSG00000177600 PMC5764779__F4 Pathway affected commonly in liver metastases irrespective of cancer types ENSG00000115956 ENSG00000170458 ENSG00000187720 ENSG00000146005 PMC6200414__F3 Phospholipid-binding tumor suppressor ANXA7 linked to the interrelated FGF8 and cyclin E pathways through Ca/phospholipid signaling in prostate cancer ENSG00000162889 ENSG00000019991 ENSG00000110395 ENSG00000120899 ENSG00000075142 ENSG00000167941 ENSG00000095321 ENSG00000168398 ENSG00000140465 ENSG00000168610 ENSG00000146648 ENSG00000116096 PMC7905841__F1 Ceramides in Metabolism: Key Lipotoxic Players ENSG00000139624 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000119537 ENSG00000148154 ENSG00000143418 PMC6850018__F1 Modeling therapy resistance via the EGFR signaling pathway ENSG00000198793 ENSG00000146648 ENSG00000069966 PMC4495601__F7 Novel drug target identification for the treatment of dementia using multi-relational association mining ENSG00000104626 ENSG00000087095 ENSG00000172680 ENSG00000170458 ENSG00000130159 ENSG00000127191 ENSG00000182667 ENSG00000026103 PMC6936066__F8 The explanation of TGFB regulates cell fate and plasticity as well as multifunctional cellular responses via SMADor non-SMAD pathways or ITGB1 pathway band with fibronectins and tenascin-C PI3K/AKT pathway ENSG00000150093 ENSG00000168036 PMC4200801__F3 Current strategies to generate tolDCs ENSG00000198793 ENSG00000107485 PMC3816662__F1 PI3K/Akt/mTOR signaling pathway ENSG00000002330 ENSG00000198793 ENSG00000136997 ENSG00000164327 ENSG00000167965 ENSG00000171791 PMC4040939__F2 Wnt pathway, sclerostin, and DKK1; effects of monoclonal antibodies on bone.(a) Scl and DKK1 bind Wnt coreceptors LRP5/6 to inhibit Wnt binding and signaling to decrease bone formation ENSG00000281324 ENSG00000162337 ENSG00000134569 PMC2692251__F2 HuR and/or AUF1 differentially regulate mRNAs encoding cell cycle and Erk1/Erk2 Mapk signaling-related genes in MCT-1–transformed cells ENSG00000169291 ENSG00000167941 PMC7933428__F7 Catalytic activity tunable ceria nanoparticles prevent chemotherapy-induced acute kidney injury without interference with chemotherapeutics ENSG00000105656 ENSG00000079999 PMC10929203__F1 Exosomes in psoriasis pathogenesis ENSG00000136688 PMC10931608__F11 Signaling pathways involving MISP ENSG00000104147 ENSG00000099812 ENSG00000168610 PMC8267809__F1 Activated PI3Kinase Delta Syndrome—A Multifaceted Disease ENSG00000177455 ENSG00000186716 ENSG00000168685 PMC3346900__F4 (A, B) Schematic view of the Fas/Fas-ligand (FasL) apoptotic signaling pathway ENSG00000115317 ENSG00000026103 PMC3236216__F8 Distinct Peripheral Blood RNA Responses to Salmonella in Pigs Differing in Salmonella Shedding Levels: Intersection of IFNG, TLR and miRNA Pathways ENSG00000213928 ENSG00000157601 ENSG00000158517 ENSG00000162772 ENSG00000141968 ENSG00000161955 ENSG00000274619 ENSG00000150782 ENSG00000157557 ENSG00000134755 ENSG00000182511 ENSG00000144802 ENSG00000172216 ENSG00000066336 ENSG00000144848 ENSG00000123610 ENSG00000196954 ENSG00000173039 ENSG00000221869 ENSG00000116717 ENSG00000043462 ENSG00000073921 ENSG00000143252 ENSG00000111537 ENSG00000117862 ENSG00000120899 ENSG00000170458 ENSG00000163131 ENSG00000135363 ENSG00000172936 ENSG00000137575 ENSG00000100365 ENSG00000108774 ENSG00000136689 PMC6593294__F1 Possible pathways underlying the DLL1/Notch signaling pathway defect ENSG00000170365 ENSG00000128272 ENSG00000283780 ENSG00000148400 ENSG00000196839 ENSG00000164690 ENSG00000137845 ENSG00000100603 PMC8679799__F1 Human NLRP1: From the shadows to center stage ENSG00000278718 ENSG00000125538 ENSG00000091592 ENSG00000142002 PMC9323564__F16 Altered Transcriptional Regulation of Glycolysis in Circulating CD8+ T Cells of Rheumatoid Arthritis Patients ENSG00000233954 ENSG00000167283 ENSG00000184752 ENSG00000148057 ENSG00000105953 ENSG00000091140 ENSG00000147123 PMC9589221__F6 Melatonin signalling in Schwann cells during neuroregeneration ENSG00000164690 PMC5553784__F3 Reactome functional interaction network corresponding to 520 genes showing differential expression in the T0 (fasting) vs T2 (7 h after eating) comparisons ENSG00000067141 ENSG00000103222 ENSG00000265972 ENSG00000162772 ENSG00000150455 ENSG00000125398 ENSG00000155011 ENSG00000197713 ENSG00000185022 ENSG00000119669 ENSG00000108349 ENSG00000105516 ENSG00000221869 ENSG00000007908 ENSG00000106829 ENSG00000108179 ENSG00000100084 ENSG00000008516 ENSG00000172602 ENSG00000144857 ENSG00000107485 ENSG00000162711 ENSG00000119508 ENSG00000153094 ENSG00000182899 ENSG00000141639 ENSG00000002746 ENSG00000288292 ENSG00000108840 ENSG00000275331 ENSG00000125414 ENSG00000105289 ENSG00000008988 ENSG00000186340 ENSG00000132326 ENSG00000043039 ENSG00000284194 ENSG00000095794 ENSG00000167114 ENSG00000138411 ENSG00000288335 ENSG00000133216 ENSG00000145604 ENSG00000050344 ENSG00000146592 ENSG00000084072 ENSG00000048052 ENSG00000074266 ENSG00000128965 PMC6121269__F2 Pathogenicity and factors associated with the disruption of the normal cellular activity ENSG00000134982 ENSG00000168036 PMC5669051__F4 Endocannabinoid System in Neurodegenerative Disorders ENSG00000159224 ENSG00000291507 ENSG00000198670 ENSG00000145020 PMC9323564__F13 Altered Transcriptional Regulation of Glycolysis in Circulating CD8+ T Cells of Rheumatoid Arthritis Patients ENSG00000145604 ENSG00000168003 ENSG00000198793 PMC12174527__F2 Metabolic Pathway of RFC ENSG00000284320 ENSG00000228716 ENSG00000100714 PMC5050510__F4 Repeatability of cortisol stress response in the European sea bass (Dicentrarchus labrax) and transcription differences between individuals with divergent responses ENSG00000113600 ENSG00000110799 ENSG00000244731 ENSG00000010278 ENSG00000088926 ENSG00000166278 ENSG00000122194 ENSG00000117322 ENSG00000185010 ENSG00000180210 ENSG00000126218 ENSG00000117525 ENSG00000173599 ENSG00000057593 ENSG00000175899 ENSG00000080618 ENSG00000198734 ENSG00000062485 PMC5669051__F1 Endocannabinoid System in Neurodegenerative Disorders ENSG00000198576 PMC5904274__F3 Molecular mechanisms of ZIKV underlying the neuropathogenesis ENSG00000117525 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000198793 ENSG00000142089 ENSG00000121060 PMC2796113__F2 Models of Merlin-dependent membrane receptor distribution in flies and mammalian cells ENSG00000186575 ENSG00000138798 ENSG00000109062 ENSG00000146648 PMC8114846__F2 Review of Recent Research on the Role of MicroRNAs in Renal Cancer ENSG00000132109 ENSG00000198793 ENSG00000050165 ENSG00000112715 ENSG00000175104 ENSG00000285379 PMC5471068__F2 Pathogenesis of ETV6/RUNX1-positive childhood acute lymphoblastic leukemia and mechanisms underlying its relapse ENSG00000198793 ENSG00000136997 ENSG00000187266 ENSG00000168610 PMC3917509__F1 The multiple roles of protein ubiquitylation ENSG00000188486 ENSG00000132646 ENSG00000130997 ENSG00000175104 PMC6977568__F1 HER2 signaling pathways in cancer cell and cardiac myocyte ENSG00000132326 PMC11351910__F7 Wnt/Beta-Catenin signaling pathway and miRNAs in pancreatic cancer ENSG00000281324 ENSG00000162337 ENSG00000006712 ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC7705175__F1 Autophagy-lysosomal pathway (ALP) PMC7069334__F1 Simplified Galactomannan biosynthetic pathway in coffee seed ENSG00000069482 ENSG00000119912 PMC3402068__F1 What Goes On Must Come Off: phosphatases gate-crash the DNA damage response ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000154920 ENSG00000188827 ENSG00000051180 ENSG00000139618 PMC4651738__F8 Schematic diagram illustrating the proposed signaling pathway ENSG00000112367 ENSG00000005381 PMC3022727__F6 IPA pathway graphical representation of Aryl Hydrocarbon Receptor Signaling ENSG00000174156 ENSG00000228716 ENSG00000170899 ENSG00000184254 ENSG00000109320 ENSG00000008394 ENSG00000145386 ENSG00000124762 ENSG00000106546 ENSG00000101868 ENSG00000059573 ENSG00000125686 ENSG00000085871 ENSG00000277897 ENSG00000105810 ENSG00000149554 ENSG00000139687 ENSG00000162599 PMC3059560__F1 Targeting the embryonic gene Cripto-1 in cancer and beyond ENSG00000156574 PMC11351910__F3 PI3K/AKT signaling pathway and miRNAs in pancreatic cancer ENSG00000138798 ENSG00000198793 ENSG00000146648 ENSG00000145113 PMC3022001__F12 Schematic representation of effect of depletion of the syntaxin-5 complex on the autophagic pathway ENSG00000265808 PMC2819159__F2 Obesity, Diet and Risk of Non-Hodgkin Lymphoma ENSG00000228716 ENSG00000116984 PMC11351910__F4 KRAS signaling pathway and miRNAs in pancreatic cancer ENSG00000136158 ENSG00000138798 ENSG00000146648 PMC11351910__F5 JAK/STAT signaling pathway and miRNAs in pancreatic cancer ENSG00000123609 ENSG00000136997 ENSG00000170677 ENSG00000007171 PMC11351910__F6 TGFB signaling pathway and miRNAs in pancreatic cancer PMC4373477__F1 Simplified diagram of the Ras/ERK pathway and SST effects through PTPs, SHP-1 and SHP-2 ENSG00000291971 ENSG00000157005 ENSG00000123268 PMC4373477__F2 Simplified diagram of PI3K/Akt pathway and SST effects through PTP SHP-1 ENSG00000002330 ENSG00000157005 PMC6122736__F7 Mechanism of XWL-1-48 inhibits growth of breast cancer cells ENSG00000188486 ENSG00000149311 PMC9173833__F35 SARS-CoV-2 infection impairs the insulin/IGF signaling pathway in the lung, liver, adipose tissue, and pancreatic cells via IRF1 ENSG00000125347 PMC4544746__F7 STALK CELL PHENOTYPE DEPENDS ON INTEGRATION OF NOTCH AND SMAD1/5 SIGNALING CASCADES ENSG00000114315 ENSG00000125968 PMC6770389__F1 The infectious spleen and kidney necrosis virus (ISKNV) induced the changes of glucose metabolism ENSG00000197713 ENSG00000122966 ENSG00000172005 ENSG00000110435 PMC4615001__F2 Mitoribosome assembly lines ENSG00000182810 ENSG00000101181 ENSG00000101546 ENSG00000197912 ENSG00000148824 PMC5797605__F1 mTOR signaling during autophagy ENSG00000177169 ENSG00000155792 ENSG00000112561 PMC5797605__F2 mTORC1 and mTORC2 complexes ENSG00000198793 ENSG00000155792 ENSG00000166278 PMC5882221__F2 Ubiquitin-mediated regulation of the core Hippo pathway components ENSG00000126016 ENSG00000118518 ENSG00000181788 ENSG00000150457 ENSG00000114019 ENSG00000131023 ENSG00000148634 ENSG00000123124 ENSG00000180667 ENSG00000069869 ENSG00000078747 ENSG00000139842 ENSG00000109670 PMC9406970__F2 Modulating Chaperone-Mediated Autophagy and Its Clinical Applications in Cancer ENSG00000081913 ENSG00000131095 PMC8076600__F4 Cytoskeleton Dynamics in Peripheral T Cell Lymphomas: An Intricate Network Sustaining Lymphomagenesis ENSG00000094631 ENSG00000070831 ENSG00000134215 ENSG00000198793 ENSG00000119969 ENSG00000087586 ENSG00000166851 ENSG00000141968 ENSG00000284984 PMC7917105__F4 Genome of Medicago polymorpha provides insights into its edibility and nutritional value as a vegetable and forage legume ENSG00000090402 ENSG00000084774 PMC5078608__F7 Ca2+Signaling Pathway Proteins that Are Regulated by Homeostatic ScalingIntracellular signaling pathways ENSG00000088256 ENSG00000111110 ENSG00000138834 ENSG00000109689 ENSG00000011566 ENSG00000156299 ENSG00000166501 ENSG00000007402 ENSG00000101333 ENSG00000165322 ENSG00000116983 ENSG00000167323 ENSG00000109320 ENSG00000070961 ENSG00000107863 ENSG00000087460 ENSG00000108179 ENSG00000186716 ENSG00000157445 ENSG00000136160 ENSG00000175175 ENSG00000146648 ENSG00000134909 ENSG00000162104 ENSG00000182389 ENSG00000145819 ENSG00000178568 PMC6913443__F2 Multifactorial regulation of hepcidin expression in hepatocytes ENSG00000170365 ENSG00000010704 ENSG00000106327 ENSG00000136869 ENSG00000168610 PMC5985159__F1 Acquired Resistance to Drugs Targeting Tyrosine Kinases ENSG00000132906 ENSG00000019991 ENSG00000138798 ENSG00000198793 ENSG00000169047 ENSG00000155792 ENSG00000140443 PMC8773742__F1 Recombinant Proteins-Based Strategies in Bone Tissue Engineering ENSG00000154342 ENSG00000170365 ENSG00000138795 ENSG00000134982 ENSG00000291837 ENSG00000168036 ENSG00000111186 ENSG00000204217 PMC8870354__F2 Drug Resistance and Endoplasmic Reticulum Stress in Hepatocellular Carcinoma ENSG00000128272 ENSG00000151012 ENSG00000100219 ENSG00000127191 PMC5994557__F1 Specific microRNAs (miRNAs) in T helper 17 (Th17) cell differentiation and targets for current treatments ENSG00000147162 ENSG00000070831 ENSG00000087085 ENSG00000103522 ENSG00000168610 ENSG00000106546 ENSG00000162594 ENSG00000141232 ENSG00000162676 ENSG00000150907 ENSG00000137265 ENSG00000175104 ENSG00000069345 PMC7431833__F6 Schematic diagram depicting the possible mechanisms ENSG00000142192 ENSG00000283100 PMC8087485__F1 Intestinal Microbiota and Liver Diseases: Insights into Therapeutic Use of Traditional Chinese Medicine ENSG00000130649 PMC7848966__F4 Crosstalk of the NF‐KB pathway involved in glioma angiogenesis with other signalling processes ENSG00000127191 PMC7505114__F3 IVM-induced PAK1/Akt/mTOR-mediated autophagy.IVM promotes degradation of PAK1 by ubiquitination/proteasome pathway, thereby inhibiting the Akt/mTOR signaling pathway ENSG00000126775 ENSG00000149269 ENSG00000198793 PMC10930821__F6 Enhancement of drug sensitivity via molecular therapies targeting tumor growth and antitumor immunity ENSG00000135446 ENSG00000105810 PMC7505114__F5 PAK1 cross regulate multiple signal pathways.RAS activation directly initiates PAK1, MAPK and PI3K/Akt pathway ENSG00000149269 ENSG00000198793 ENSG00000168036 PMC10930821__F5 Molecular mechanisms of immunogenic cell death and tumor-specific immune activation via unfolded protein response (UPR) activation by anticancer drugs ENSG00000111537 ENSG00000128272 ENSG00000175591 ENSG00000089041 ENSG00000189403 ENSG00000136869 ENSG00000171051 PMC10930821__F3 Summary model for the c-Jun N-terminal kinase (JNK)/c-Jun/activator protein 1 (AP-1)-mediated signaling pathway in anticancer drug-induced cell death ENSG00000026103 PMC11772327__F1 Proposed biosynthetic pathway of LC‐alkanes pentadecane and heptadecane in Pogostemon cablin ENSG00000147869 ENSG00000100294 ENSG00000026103 PMC5584126__F8 CD55 regulates self-renewal and cisplatin resistance in endometrioid tumors ENSG00000012048 ENSG00000169071 ENSG00000196352 PMC10930821__F1 Common intrinsic and extrinsic apoptotic signaling pathways induced by anticancer drugs ENSG00000102871 ENSG00000168040 ENSG00000115317 PMC4052759__F1 Autophagy regulates p62/SQSTM1 levels to control multiple pro-oncogenic signaling pathways ENSG00000177169 ENSG00000123395 ENSG00000198793 ENSG00000145782 ENSG00000057663 ENSG00000079999 PMC4742205__F7 INSM1 increases N-myc stability and oncogenesis via a positive-feedback loop in neuroblastoma ENSG00000173404 ENSG00000164690 PMC7994325__F2 Importance of ICOS+ Th1 cells in ICI therapy ENSG00000111537 ENSG00000134982 ENSG00000163599 PMC7470804__F8 Proposed mechanisms for the GluOC therapeutic effects on hyperglycemia and hepatic steatosis in KKAy mice ENSG00000042832 ENSG00000150907 ENSG00000026103 PMC7378634__F1 Cellular sources and effects of IL-22 ENSG00000105397 ENSG00000115415 ENSG00000168610 PMC10525260__F3 Multi-Faceted Role of Cancer-Associated Adipocytes in Colorectal Cancer ENSG00000154342 ENSG00000081041 ENSG00000142611 ENSG00000163739 ENSG00000169884 ENSG00000187772 ENSG00000152952 ENSG00000168610 PMC4826209__F6 WWOX modulates the ATR-mediated DNA damage checkpoint response ENSG00000149311 ENSG00000175054 ENSG00000078747 ENSG00000138385 PMC8721139__F1 Potential of Ferroptosis-Targeting Therapies for Alzheimer’s Disease: From Mechanism to Transcriptomic Analysis ENSG00000168003 ENSG00000116044 ENSG00000151012 ENSG00000205221 ENSG00000167468 ENSG00000115107 PMC4450766__F5 EGFR pathway and the model of the effect of EGFR/MEK/EGFR + MEK inhibition on the pathway in RAS‐active NSCLC cell lines ENSG00000146648 PMC7723971__F1 ROS/NLRP3 signaling pathway participates in sepsis-related immune responses ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC10960420__F12 Patterns of effectiveness of C ENSG00000049768 ENSG00000168610 PMC9664061__F1 Promising research direction for colorectal cancer immunotherapy: The regulatory mechanism of CCL5 in colorectal cancer ENSG00000178860 ENSG00000169245 ENSG00000168036 ENSG00000168610 PMC4613973__F8 Working models for the failure of PRL-PRLR-JAK2-STAT5 signaling to activate proliferation in adult human Beta-cells ENSG00000113494 PMC9999652__F3 Exosomal cargos-mediated metabolic reprogramming in tumor microenvironment ENSG00000131473 ENSG00000291507 ENSG00000136997 PMC9999652__F7 Exosomal cargos-mediated metabolic reprogramming in tumor microenvironment ENSG00000182718 ENSG00000161905 ENSG00000253352 ENSG00000103257 ENSG00000126778 PMC8641784__F3 SUMO-specific Isopeptidases Tuning Cardiac SUMOylation in Health and Disease ENSG00000161956 ENSG00000079387 ENSG00000163904 ENSG00000112701 ENSG00000063978 ENSG00000188612 ENSG00000081189 ENSG00000140464 ENSG00000184900 PMC9999652__F8 Exosomal cargos-mediated metabolic reprogramming in tumor microenvironment ENSG00000120913 PMC3248866__F2 HPV 16 E5 enhances growth factor signalling pathways ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC9999652__F5 Exosomal cargos-mediated metabolic reprogramming in tumor microenvironment ENSG00000198793 PMC12115344__F1 Diagrammatic overview of key pathways involved in ALD ENSG00000162711 ENSG00000183735 ENSG00000164430 ENSG00000168610 ENSG00000026103 PMC7971547__F3 Role of inflammasomes/pyroptosis and PANoptosis during fungal infection ENSG00000162711 ENSG00000124256 ENSG00000187796 ENSG00000163568 ENSG00000125538 ENSG00000172936 ENSG00000125347 PMC7905024__F1 CGAS-STING and TLR9 signaling in response to the recognition of host-derived self-DNA as a DAMP ENSG00000239732 ENSG00000164430 ENSG00000189403 ENSG00000172936 ENSG00000157625 ENSG00000150455 ENSG00000175104 PMC9641212__F1 Immune response induced by novel coronavirus infection ENSG00000137033 ENSG00000168404 ENSG00000125347 ENSG00000164305 PMC6955855__F5 Terpene and terpenoids biosynthesis ENSG00000067064 ENSG00000110921 ENSG00000197429 ENSG00000148377 PMC11395325__F7 Proposed mechanism by which HAE improves lactation ENSG00000155792 ENSG00000026103 PMC8867093__F2 Exploring the Metabolic Landscape of AML: From Haematopoietic Stem Cells to Myeloblasts and Leukaemic Stem Cells PMC4030844__F1 Simplified schema of interconnections between small ubiquitin-related modifier (SUMO) pathway proteins and other factors regulating androgen receptor (AR)-dependent transcription ENSG00000079387 ENSG00000163904 ENSG00000184900 PMC4030844__F2 AR-independent promotion of prostate cancer (PCa) cell proliferation and angiogenesis by the SUMO pathway ENSG00000161956 ENSG00000079387 ENSG00000116030 PMC6102867__F2 Regulation network of circRNAs in cancer ENSG00000023445 ENSG00000157827 ENSG00000070831 ENSG00000078747 ENSG00000168036 ENSG00000123374 ENSG00000133740 ENSG00000105810 ENSG00000112715 ENSG00000168610 ENSG00000146648 ENSG00000131023 PMC9523121__F1 Hypothalamic endoplasmic reticulum stress in schizophrenia and antipsychotic-induced weight gain: A narrative review ENSG00000128272 ENSG00000144895 ENSG00000115138 ENSG00000100219 PMC6433691__F7 Model of JS‐K‐induced anti‐tumour activity in gastric cancer ENSG00000120868 PMC4633914__F1 Functions and interactions of CIP2A and the “oncogenic nexus” of CIP2A are presented in a schematic representation of the major interacting partners of “oncogenic nexus” of CIP2A protein ENSG00000150907 ENSG00000105568 ENSG00000163507 PMC9658791__F3 Proteostasis Network: A Global Therapeutic Target for Neuroprotection after Spinal Cord Injury ENSG00000128272 ENSG00000100219 PMC5676474__F7 Oxidative Stress Alters the Profile of Transcription Factors Related to Early Development on In Vitro Produced Embryos ENSG00000116044 ENSG00000167468 ENSG00000116717 ENSG00000123562 PMC10968836__F2 Comparison of the signalling pathways triggered by TNFR1, Fas and TRAIL agonist receptors ENSG00000137275 ENSG00000102871 ENSG00000127191 ENSG00000026103 PMC3956136__F1 Canonical Wnt B catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC10968836__F3 TRAIL canonical signalling pro-apoptotic pathway ENSG00000137275 ENSG00000168040 PMC11812559__F2 Beyond Tumors: The Pivotal Role of TRIM Proteins in Chronic Non-Tumor Lung Diseases PMC10968836__F4 DR5 non-apoptotic signalling pathways ENSG00000108691 ENSG00000137275 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 ENSG00000121966 PMC10968836__F5 TRAIL-induced non-canonical pro-tumoral signalling via DR5 secondary complex formation ENSG00000108691 ENSG00000178772 ENSG00000102871 ENSG00000291971 ENSG00000198793 ENSG00000163914 ENSG00000132478 ENSG00000067900 ENSG00000168040 ENSG00000127191 ENSG00000168610 ENSG00000146648 PMC6829074__F1 microRNAs in Mycobacterial Infection: Modulation of Host Immune Response and Apoptotic Pathways ENSG00000102871 ENSG00000150907 ENSG00000168040 ENSG00000127191 PMC6829074__F2 microRNAs in Mycobacterial Infection: Modulation of Host Immune Response and Apoptotic Pathways ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000137496 PMC9043558__F1 Ror-Family Receptors in Development, Tissue Regeneration and Age-Related Disease ENSG00000169071 ENSG00000185483 PMC3929401__F1 Deficient Phosphorylation of Stat1 in Leukocytes Identifies Neutralizing Antibodies in Multiple Sclerosis Patients Treated with Interferon-Beta ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000157601 ENSG00000168610 ENSG00000142166 PMC4394599__F2 Molecular pathway of glycolysis in NSPCs ENSG00000074800 ENSG00000198793 ENSG00000136997 ENSG00000078237 ENSG00000284194 ENSG00000159399 PMC4394599__F3 Molecular pathway of glutaminolysis in NSPCs ENSG00000136997 ENSG00000017483 ENSG00000089163 ENSG00000115419 PMC3712731__F4 Display of wild-type and disease pathway diagrams ENSG00000144749 ENSG00000105401 ENSG00000138798 ENSG00000124181 ENSG00000146648 PMC5414760__F6 Potential role of CBX2 in the regulation of sex development ENSG00000116918 ENSG00000162552 ENSG00000136891 ENSG00000187189 ENSG00000173894 ENSG00000125398 ENSG00000121068 ENSG00000168066 ENSG00000171100 ENSG00000134595 ENSG00000248099 ENSG00000157240 PMC9357883__F3 Molecular mechanisms underlying the role of hypoxia-inducible factor-1 A in metabolic reprogramming in renal fibrosis ENSG00000198793 PMC10193374__F1 In wound healing, CTHRC1 can recruit additional M2 macrophages to the wound site to promote skin repair and activate the TGFB and Notch pathways ENSG00000164932 ENSG00000135547 ENSG00000148400 ENSG00000134982 ENSG00000172269 ENSG00000198793 ENSG00000067900 ENSG00000273529 ENSG00000114315 ENSG00000105723 PMC7376803__F1 AMH and FSH signaling pathways, cellular outcomes, and main functions in IVF practice ENSG00000104899 ENSG00000292096 ENSG00000170365 ENSG00000087245 ENSG00000137834 ENSG00000115297 ENSG00000291971 ENSG00000135409 ENSG00000150907 ENSG00000168036 ENSG00000123374 PMC5942524__F2 Organismal Injury and Abnormalities, Cardiovascular Disease, Nutritional Disease Ingenuity Pathway Analysis (IPA) Network ENSG00000276825 ENSG00000112038 ENSG00000226275 ENSG00000186716 ENSG00000169032 ENSG00000276996 ENSG00000073756 ENSG00000149295 PMC9554349__F3 Genetic and pharmacological tools to study the role of discoidin domain receptors in kidney disease ENSG00000135218 ENSG00000168036 ENSG00000168610 PMC5942524__F3 Hereditary Disorder, Organismal Injury and Abnormalities, Respiratory Disease Ingenuity Pathway Analysis (IPA) Network ENSG00000115008 ENSG00000132693 PMC8375320__F3 Strong as a Hippo’s Heart: Biomechanical Hippo Signaling During Zebrafish Cardiac Development ENSG00000018408 ENSG00000103335 PMC8375320__F1 Strong as a Hippo’s Heart: Biomechanical Hippo Signaling During Zebrafish Cardiac Development ENSG00000154864 ENSG00000018408 ENSG00000150457 ENSG00000037280 ENSG00000131023 ENSG00000103335 PMC3881602__F1 Interplay between regulatory T cells and metabolism in immune regulation ENSG00000135218 ENSG00000163599 ENSG00000198793 ENSG00000164327 ENSG00000107485 ENSG00000049768 PMC6407036__F3 Biomarkers in the Pathways in cancer ENSG00000132906 ENSG00000002330 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000164305 ENSG00000170365 ENSG00000110395 ENSG00000113318 ENSG00000172005 ENSG00000095002 ENSG00000127948 ENSG00000164949 ENSG00000122008 PMC6407036__F4 MiRNAs involve in different types of cancers and colorectal cancer biomarkers ENSG00000136158 ENSG00000149311 ENSG00000169554 ENSG00000185634 ENSG00000141627 ENSG00000156103 ENSG00000179091 ENSG00000134982 ENSG00000124766 ENSG00000171791 PMC4553385__F2 Treg suppression ENSG00000134982 PMC5661628__F1 CS synthesis ENSG00000147408 ENSG00000069482 ENSG00000123989 ENSG00000176022 ENSG00000285395 ENSG00000198108 ENSG00000131873 ENSG00000109956 PMC4621004__F1 RAGE signaling pathways ENSG00000070831 ENSG00000291971 ENSG00000189403 ENSG00000198670 PMC4306304__F1 Hereditary hemorrhagic telangiectasia is a genetically heterogeneous disorder caused by mutations in several genes in the TGFB/BMP signaling pathway ENSG00000170365 ENSG00000125968 PMC8668794__F3 Gene expression and epigenetic responses of the marine Cladoceran, Evadne nordmanni, and the copepod, Acartia clausi, to elevated CO2 PMC8148155__F1 Oral Supplementation of an Alkylglycerol Mix Comprising Different Alkyl Chains Effectively Modulates Multiple Endogenous Plasmalogen Species in Mice ENSG00000197601 ENSG00000133027 PMC7947364__F1 Summary of the cellular metabolic effects of hyperglycemia in cancer ENSG00000169710 ENSG00000148429 ENSG00000146648 ENSG00000159399 ENSG00000140443 PMC3774704__F1 Galectin-3 is a regulator of metaflammation in adipose tissue and pancreatic islets ENSG00000162711 ENSG00000136869 PMC2810660__F1 Autophagy and NFKB fight for fate ENSG00000162924 ENSG00000131323 ENSG00000127191 PMC5541893__F3 Mechanisms involved in initiation, perpetuation, and resolution of inflammatory responses ENSG00000143546 ENSG00000171049 ENSG00000005381 PMC7564048__F3 Crosstalk with the TGFB/BMP SMAD pathway at focal adhesions (FA) ENSG00000204217 PMC6480119__F9 Schematic diagram of EGCG anti-tumor mechanisms based on reverse docking ENSG00000145632 ENSG00000104365 ENSG00000065675 ENSG00000137193 ENSG00000065559 ENSG00000197442 ENSG00000277273 ENSG00000105639 ENSG00000007171 ENSG00000186716 ENSG00000134070 ENSG00000123374 ENSG00000041880 ENSG00000173846 ENSG00000120868 ENSG00000184216 PMC9143803__F2 New Insights into the Pathogenesis of Giant Cell Arteritis: Mechanisms Involved in Maintaining Vascular Inflammation ENSG00000168329 ENSG00000108691 ENSG00000275385 ENSG00000170458 ENSG00000137077 ENSG00000138755 ENSG00000126353 ENSG00000112149 ENSG00000049768 ENSG00000121807 PMC8466925__F2 Polymorphism in various potential genes on polycystic ovary syndrome susceptibility and pathogenesis ENSG00000129214 ENSG00000138039 PMC8554507__F1 Modular map of Bradykinin-mediated inflammatory signaling network ENSG00000170909 ENSG00000078369 ENSG00000198793 ENSG00000173039 ENSG00000088256 ENSG00000213341 ENSG00000155903 ENSG00000112715 ENSG00000121879 ENSG00000087460 ENSG00000089159 ENSG00000016602 ENSG00000095303 ENSG00000186469 PMC11101339__F4 KRAS pathway and KRAS inhibitors ENSG00000198793 PMC11101339__F5 Main mechanisms of therapy targeting TME in SMARCA4-UT ENSG00000111537 ENSG00000134982 ENSG00000138755 ENSG00000026103 PMC7056627__F1 LncRNA-GAS5/miR-221-3p/DKK2 Axis Modulates ABCB1-Mediated Adriamycin Resistance of Breast Cancer via the Wnt/Beta-Catenin Signaling Pathway ENSG00000155011 ENSG00000168036 PMC2447903__F8 TWEAK killing ENSG00000102871 ENSG00000131323 ENSG00000168040 ENSG00000127191 PMC7599155__F2 Dna2 is an essential gatekeeper to HR-dependent restart of stalled replication forks ENSG00000138346 ENSG00000140451 ENSG00000051180 PMC8136122__F5 TGFB1: Gentlemanly orchestrator in idiopathic pulmonary fibrosis (Review) ENSG00000134982 ENSG00000168036 PMC8136122__F6 TGFB1: Gentlemanly orchestrator in idiopathic pulmonary fibrosis (Review) ENSG00000163814 ENSG00000146648 PMC9364940__F1 Ionizing Radiation-Induced Ferroptosis Based on Nanomaterials ENSG00000149311 ENSG00000164430 ENSG00000151012 ENSG00000167468 ENSG00000111684 PMC8271933__F1 Targeting the PI3K/AKT/mTOR Signaling Pathway in Lung Cancer: An Update Regarding Potential Drugs and Natural Products ENSG00000171791 PMC9225571__F1 Yes-Associated Protein in Psoriasis and Skin Tumor Pathogenesis ENSG00000109321 ENSG00000026103 PMC8136122__F4 TGFB1: Gentlemanly orchestrator in idiopathic pulmonary fibrosis (Review) ENSG00000100234 ENSG00000168036 PMC5838215__F1 Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder ENSG00000004975 ENSG00000087095 ENSG00000281324 ENSG00000005339 ENSG00000162337 ENSG00000168036 ENSG00000101266 ENSG00000196470 ENSG00000182621 ENSG00000175029 ENSG00000116161 ENSG00000100592 ENSG00000100387 ENSG00000155011 ENSG00000070770 ENSG00000155760 PMC8271933__F2 Targeting the PI3K/AKT/mTOR Signaling Pathway in Lung Cancer: An Update Regarding Potential Drugs and Natural Products ENSG00000166278 PMC5838215__F2 Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder ENSG00000163637 ENSG00000087095 ENSG00000112576 ENSG00000281324 ENSG00000005339 ENSG00000162337 ENSG00000168036 ENSG00000196470 ENSG00000137841 ENSG00000221823 ENSG00000148660 ENSG00000100592 ENSG00000100387 ENSG00000070770 ENSG00000166501 ENSG00000155760 PMC8136122__F2 TGFB1: Gentlemanly orchestrator in idiopathic pulmonary fibrosis (Review) ENSG00000128272 ENSG00000145147 ENSG00000163430 ENSG00000163914 ENSG00000086991 ENSG00000189403 ENSG00000077463 ENSG00000288455 PMC6230982__F2 Metabolic pathways involved in anticancer drug resistance ENSG00000157764 ENSG00000092621 ENSG00000198793 ENSG00000169710 ENSG00000115419 ENSG00000159399 PMC9028275__F3 Entanglement between Mitochondrial DNA and Tumor Metastasis ENSG00000239732 ENSG00000164430 ENSG00000108688 ENSG00000112715 PMC3288605__F2 Pathway of formation and catabolism of HDL particles ENSG00000100979 PMC2782733__F2 EGFR signaling through the PI3K/Akt pathway ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC7760552__F2 Release of TEX and their molecular cargo composition ENSG00000134013 ENSG00000163914 ENSG00000146678 ENSG00000026508 ENSG00000010278 ENSG00000135404 ENSG00000115461 PMC7225257__F1 Recent mechanisms of resistance identified in lung adenocarcinoma ENSG00000143799 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000105613 ENSG00000135414 ENSG00000139618 PMC7219929__F3 Schematic depicting the response of steroidogenic cells to stressors such as polycyclic aromatic hydrocarbons and ROS ENSG00000185591 ENSG00000079999 PMC10529884__F1 Report from the 24th Annual Western Canadian Gastrointestinal Cancer Consensus Conference on Colorectal Cancer, Richmond, British Columbia, 28–29, October 2022 ENSG00000157764 ENSG00000095002 ENSG00000122512 PMC9510994__F8 Integrated volatile metabolomic and transcriptomic analysis provides insights into the regulation of floral scents between two contrasting varieties of Lonicera japonica ENSG00000110921 ENSG00000197429 ENSG00000113161 PMC10296705__F2 Biosynthesis pathways of isoprenoids and the biosensors that are responsive to isoprenoids and their precursors ENSG00000166402 ENSG00000197429 PMC5917100__F1 Viruses and the Autophagy Pathway ENSG00000284099 ENSG00000099940 PMC6438930__F2 Therapeutic targeting of glycolysis, lipid and redox metabolism in CSCs ENSG00000135218 ENSG00000115419 ENSG00000026103 PMC8441355__F6 Protective effect of Salidroside on hypoxia‐related liver oxidative stress and inflammation via Nrf2 and JAK2/STAT3 signaling pathways ENSG00000181019 ENSG00000130649 ENSG00000168610 PMC8149954__F1 Ironing Out the Details: How Iron Orchestrates Macrophage Polarization ENSG00000291873 ENSG00000162711 ENSG00000108691 ENSG00000128272 ENSG00000125538 ENSG00000086991 PMC3268617__F2 Dys–Syn–nNOS pathway and miRNAs coordinate the muscle differentiation program ENSG00000100811 ENSG00000101868 ENSG00000009709 PMC3954825__F2 DISC1 as a key lead in studying cortical development and associated brain disorders ENSG00000142192 ENSG00000065361 ENSG00000134982 ENSG00000168036 ENSG00000173406 PMC3355930__F1 Prostaglandin E2 (PGE2) biosynthesis and signaling PMC11750270__F8 Therapeutic potential of monomethyl fumarate and aluminum ion combination in alleviating inflammation and oxidative stress in psoriasis ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC7757125__F9 Metabolic pathways connecting gene expression, DNA methylation, and targeted metabolomic data ENSG00000143158 ENSG00000005882 ENSG00000169710 ENSG00000103150 ENSG00000076555 ENSG00000091140 ENSG00000060762 ENSG00000062485 PMC6230982__F1 Metabolic pathways associated with cancer ENSG00000180210 ENSG00000125166 ENSG00000092621 ENSG00000169710 ENSG00000115419 ENSG00000159399 PMC5916355__F5 Proposed model for nicotine-induced synaptic plasticity in the OFC ENSG00000178568 PMC7002027__F2 Phagocytosis checkpoints as new targets for cancer immunotherapy ENSG00000239732 ENSG00000164430 ENSG00000198053 ENSG00000104972 ENSG00000273686 PMC3996455__F1 Treg functional stability and its responsiveness to the microenvironment ENSG00000103266 ENSG00000198793 ENSG00000172936 ENSG00000049768 ENSG00000168610 PMC10280140__F11 TGF‐B‐induced PI3K/AKT/mTOR pathway ENSG00000169047 ENSG00000198793 ENSG00000144848 ENSG00000100985 ENSG00000057663 PMC9507923__F2 QishenYiqi dripping pill protects against myocardial ischemia/reperfusion injury via suppressing excessive autophagy and NLRP3 inflammasome based on network pharmacology and experimental pharmacology ENSG00000142192 ENSG00000146648 PMC4734073__F4 Strategies evolved by Staphylococcus aureus to counteract innate immune response ENSG00000171049 ENSG00000163734 ENSG00000006747 ENSG00000137845 PMC5681734__F1 NRG–ErbB signaling pathway ENSG00000065361 ENSG00000198793 ENSG00000158458 ENSG00000178568 PMC11873031__F5 Experimental design, analysis and validation ENSG00000167112 PMC2989686__F4 Canonical pathways for cardiovascular disease ENSG00000080618 ENSG00000198125 ENSG00000122194 ENSG00000276838 PMC3025468__F11 Compartmentalization of TNF-R1 signalling and A-SMase activation ENSG00000132906 ENSG00000102871 ENSG00000168040 ENSG00000164305 PMC5173045__F7 Proteinase-activated receptor 2 promotes TGF-Beta-dependent cell motility in pancreatic cancer cells by sustaining expression of the TGFB type I receptor ALK5 PMC5721944__F2 Hypothetical schematic connecting basal IP3R mediated Ca2+ release to protein translation, via AMPK and the TOR signalling pathway ENSG00000156026 PMC6914886__F6 The proposed mechanism by which green tea acts against NAFLD ENSG00000135218 ENSG00000150907 ENSG00000113161 ENSG00000136869 ENSG00000285070 ENSG00000175567 ENSG00000175104 ENSG00000123983 PMC6514668__F1 Schematic representation of the autophagy pathway from reference by Seiliez et al ENSG00000152348 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC3941218__F1 Insulin- and IGF-1-signaling pathways ENSG00000132906 ENSG00000002330 ENSG00000169047 ENSG00000136111 ENSG00000140443 PMC7113111__F1 Signaling pathways from three ER transmembrane stress sensors during unfolded protein response (UPR) in schizophrenia ENSG00000128272 ENSG00000144895 ENSG00000132478 ENSG00000127191 PMC4726830__F3 Emerging targets for glioblastoma stem cell therapy ENSG00000291971 ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC4120710__F6 Motility, Survival and Proliferation ENSG00000070831 ENSG00000291971 PMC8149954__F2 Ironing Out the Details: How Iron Orchestrates Macrophage Polarization ENSG00000178127 ENSG00000291873 ENSG00000139180 ENSG00000074800 ENSG00000117118 ENSG00000142599 ENSG00000159399 PMC8149954__F3 Ironing Out the Details: How Iron Orchestrates Macrophage Polarization ENSG00000171720 PMC12000394__F0 Molecular mechanisms of HBsAg suppression of the IFNB signaling pathway and triggering of early autophagy ENSG00000183735 ENSG00000099940 PMC11276560__F5 DEGs in selenium metabolic pathways of KEGG metabolic pathway map ENSG00000110395 ENSG00000007908 ENSG00000116761 PMC2566525__F8 Schematic view of part of the IGF-1 and integrin signaling pathway genes transcribed by hNCC ENSG00000002330 ENSG00000198062 PMC5870602__F8 Dorsal root ganglion neurons regulate the transcriptional and translational programs of osteoblast differentiation in a microfluidic platform ENSG00000242252 ENSG00000164761 ENSG00000291837 ENSG00000168036 ENSG00000108821 PMC11863469__F3 Signaling pathways in GBM ENSG00000149311 ENSG00000175054 ENSG00000134982 ENSG00000198793 ENSG00000171540 PMC3335800__F8 MEKK1-MKK4-JNK-AP1 Pathway Negatively Regulates Rgs4 Expression in Colonic Smooth Muscle Cells ENSG00000125538 ENSG00000177606 ENSG00000117152 PMC8875960__F1 Druggable Molecular Pathways in Chronic Lymphocytic Leukemia ENSG00000105369 ENSG00000186716 ENSG00000197943 ENSG00000010671 PMC8178581__F2 Notch signaling pathway involvement in innate lymphoid cell biology ENSG00000162594 ENSG00000111537 ENSG00000139187 ENSG00000107485 ENSG00000056736 ENSG00000114315 ENSG00000137845 ENSG00000135144 ENSG00000106829 PMC3374592__F1 Endocytic control of growth factor signalling: multivesicular bodies as signalling organelles ENSG00000291971 ENSG00000136997 PMC8178581__F1 Notch signaling pathway involvement in innate lymphoid cell biology ENSG00000122025 ENSG00000148400 ENSG00000109906 PMC8875960__F4 Druggable Molecular Pathways in Chronic Lymphocytic Leukemia ENSG00000023445 ENSG00000104856 ENSG00000131323 ENSG00000006062 ENSG00000127191 PMC7726878__F1 TLR-mediated signaling pathways in response to HSV ENSG00000174125 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000146648 ENSG00000276561 ENSG00000164342 PMC7726878__F2 Responses of TLRs to EBV and HCMV ENSG00000174125 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC7704407__F4 Proposed pathways of how cAMP and Ca2+ interact and result in increased AQP4 expression via Gs and Gq/11 in the pathology of HE during ALF ENSG00000171885 PMC7214667__F1 Janus kinase (JAK)-Signal transducer and activator of transcription (STAT) signaling pathway and its inhibition with jakinibs in synovial fibroblasts ENSG00000169248 ENSG00000169245 ENSG00000145623 ENSG00000099985 ENSG00000105397 ENSG00000149968 ENSG00000115415 ENSG00000138755 ENSG00000168610 PMC8616039__F1 Emerging Therapeutic Landscape of Peripheral T-Cell Lymphomas Based on Advances in Biology: Current Status and Future Directions ENSG00000198793 PMC1852708__F6 Illustration of key proteins in the Rho GTPase signal–transduction pathway, focusing on the KALRN, CDGAP, and MYLK genes ENSG00000070831 ENSG00000163914 ENSG00000133216 PMC3514620__F2 DNA repair pathways and implicated proteins ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000083093 ENSG00000187790 ENSG00000138385 PMC9606818__F2 Effect of narcotics on ferroptosis-related molecular mechanisms and signalling pathways ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000115107 ENSG00000115419 ENSG00000167419 PMC10537080__F2 Critical role of platelet in cancer progression and metastasis ENSG00000231179 ENSG00000162692 ENSG00000204520 PMC7982411__F1 MEK-mitogen activated protein kinase–extracellular signal-regulated kinase (ERK) signaling cascade of the mitogen-activated protein kinase (MAPK) pathway and phosphoinositide 3-kinase (PI3K)–AKT-serine/threonine protein kinase Akt pathway ENSG00000198793 ENSG00000169032 PMC6627192__F5 Ingenuity Pathway Analysis integrating differentially expressed genes and microRNAs between imatinib-naïve (IM-n) and imatinib-resistant (IM-r) gastrointestinal stromal tumor (GIST) samples ENSG00000137804 ENSG00000165891 ENSG00000125148 ENSG00000134982 ENSG00000131153 ENSG00000129173 ENSG00000112312 ENSG00000094804 ENSG00000065328 ENSG00000046889 ENSG00000143768 ENSG00000101003 ENSG00000174059 ENSG00000080839 PMC8533171__F8 Expression Profiles and Prognostic Value of FABPs in Colorectal Adenocarcinomas ENSG00000019991 ENSG00000070831 ENSG00000134982 ENSG00000143878 ENSG00000169047 ENSG00000168036 ENSG00000166484 ENSG00000147854 ENSG00000151702 ENSG00000110148 ENSG00000100387 ENSG00000135446 ENSG00000143476 ENSG00000167986 ENSG00000183742 ENSG00000028528 ENSG00000105810 ENSG00000124209 ENSG00000175305 ENSG00000109670 PMC2720036__F1 Selective Raf Inhibition in Cancer Therapy ENSG00000002330 ENSG00000157764 ENSG00000291971 ENSG00000138777 ENSG00000171791 PMC3938170__F1 Folate pathway ENSG00000228716 ENSG00000110195 PMC2078333__F1 Summary of known actions of activated ras-p21 in cells, beginning (top, left) when a growth factor binds to its cell receptor ENSG00000177606 ENSG00000136997 PMC3443512__F8 TARGETING THE eIF4A RNA HELICASE BLOCKS TRANSLATION OF THE MUC1-C ONCOPROTEIN ENSG00000198793 ENSG00000146648 PMC8303465__F1 Sex Maintenance in Mammals ENSG00000162552 ENSG00000104899 ENSG00000125398 ENSG00000137090 ENSG00000134363 PMC4290704__F1 Signalling pathway and endogenous antagonists of IL-1B and IL-18 ENSG00000115590 ENSG00000125538 ENSG00000172936 ENSG00000137496 PMC2577435__F9 Signaling from LMP1 and TLR to IRF7 activation ENSG00000239732 ENSG00000172936 ENSG00000175104 ENSG00000127191 ENSG00000276561 PMC1501125__F1 WNT Pathway in Colorectal Carcinomas Stratified by Microsatellite Instability ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC5890151__F2 Treg likely promote tissue repair and regeneration in a tissue-specific manner ENSG00000102962 ENSG00000107562 ENSG00000137033 ENSG00000109321 ENSG00000146648 ENSG00000277943 PMC2720036__F5 Selective Raf Inhibition in Cancer Therapy ENSG00000064490 ENSG00000111057 ENSG00000104147 ENSG00000002330 ENSG00000117153 ENSG00000291971 ENSG00000105401 ENSG00000134308 ENSG00000171791 ENSG00000166484 ENSG00000148484 ENSG00000062524 ENSG00000141968 ENSG00000171345 ENSG00000108061 ENSG00000138834 ENSG00000100385 ENSG00000103479 ENSG00000125249 ENSG00000104980 ENSG00000149269 ENSG00000136997 ENSG00000124181 ENSG00000139687 ENSG00000126458 ENSG00000133818 ENSG00000187678 ENSG00000136158 ENSG00000171105 ENSG00000157764 ENSG00000170027 ENSG00000078369 ENSG00000114757 ENSG00000127445 ENSG00000101161 ENSG00000176884 ENSG00000141480 ENSG00000171435 ENSG00000067606 ENSG00000185532 ENSG00000184371 ENSG00000146648 ENSG00000186469 PMC5130114__F1 Disorders of the mTORC1 signaling pathway PMC7231083__F1 Type I interferon immune response ENSG00000239732 ENSG00000088888 ENSG00000105397 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC6731276__F1 Pathway altered on both transcriptomic and epigenomic levels ENSG00000175868 ENSG00000134982 ENSG00000160013 ENSG00000146469 ENSG00000158748 ENSG00000176533 ENSG00000043591 ENSG00000064989 ENSG00000185231 ENSG00000115138 ENSG00000113749 ENSG00000166603 ENSG00000186469 PMC7231083__F3 Evasion and inhibition of respiratory virus-induced IFN-I signaling ENSG00000088888 ENSG00000105397 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000164342 PMC4728993__F1 Metabolic pathway of phenylalanine (Phe) ENSG00000125166 ENSG00000171759 PMC4339543__F2 The Role of the Protein Tyrosine Phosphatase SHP2 in Cardiac Development and Disease ENSG00000171105 ENSG00000291971 PMC139100__F8 Gelsolin-induced epithelial cell invasion is dependent on Ras–Rac signaling ENSG00000129219 ENSG00000143398 ENSG00000115904 ENSG00000165527 PMC4280834__F2 Proposed biosynthetic pathway of diphthamide ENSG00000148399 ENSG00000134146 ENSG00000154813 ENSG00000108963 PMC8447515__F6 Cancer and diabetes: the interlinking metabolic pathways and repurposing actions of antidiabetic drugs ENSG00000198793 ENSG00000168610 PMC8847900__F2 Human biosynthetic pathway for trace amines and catecholamines ENSG00000123454 ENSG00000141744 PMC5569945__F2 Role of mTORC1-S6K1 signaling pathway in regulation of hematopoietic stem cell and acute myeloid leukemia ENSG00000143761 ENSG00000169047 ENSG00000145979 ENSG00000284161 ENSG00000239282 PMC5569945__F3 Role of mTORC1-S6K1 signaling pathway in regulation of hematopoietic stem cell and acute myeloid leukemia ENSG00000169047 ENSG00000145979 PMC9290485__F3 Metabolomics reveals biomarkers in human urine and plasma to predict cytochrome P450 2D6 (CYP2D6) activity ENSG00000165841 ENSG00000197408 ENSG00000140505 PMC7391788__F7 Ingenuity pathway analysis of genes/molecules that are regulated by thymoquinone in relation to Alzheimer’s disease and inflammation (A), and osteoarthritis and inflammation (B) ENSG00000132906 ENSG00000170458 ENSG00000135446 ENSG00000104320 ENSG00000123374 ENSG00000136869 ENSG00000171791 ENSG00000005381 ENSG00000168610 ENSG00000164305 PMC3359641__F3 Prediction of susceptibility to major depression by a model of interactions of multiple functional genetic variants and environmental factors ENSG00000100811 ENSG00000291972 ENSG00000197442 ENSG00000175104 ENSG00000203857 ENSG00000064300 PMC8139735__F11 An Integrated Analysis of Network Pharmacology, Molecular Docking, and Experiment Validation to Explore the New Candidate Active Component and Mechanism of Cuscutae Semen-Mori Fructus Coupled-Herbs in Treating Oligoasthenozoospermia ENSG00000169291 ENSG00000171791 ENSG00000171345 PMC6004395__F3 ABA-dependent signaling pathway in response to temperature stress ENSG00000105722 ENSG00000136997 ENSG00000163788 PMC4350902__F3 Schematic depiction of PTEN functions in nucleus and cytosol with regard to its posttranslational modifications ENSG00000134982 ENSG00000131507 ENSG00000051180 PMC5501692__F3 Human endogenous retrovirus-derived gene that can contribute to oncogenesis by activating the ERK pathway and inducing migration and invasion ENSG00000136158 ENSG00000120875 ENSG00000244405 ENSG00000175832 ENSG00000136997 ENSG00000175592 ENSG00000187678 PMC7991784__F1 HBV-induced lipid metabolism changes in hepatocytes ENSG00000151726 ENSG00000130164 ENSG00000042832 ENSG00000167910 ENSG00000113161 ENSG00000099194 ENSG00000102172 ENSG00000026103 PMC7991784__F2 Changes in proteins or metabolites of lipid metabolism pathway affect the life cycle of HBV: potential targets for HBV suppression ENSG00000173599 ENSG00000113161 ENSG00000104549 ENSG00000026103 PMC3606625__F1 EGFR-Targeted Therapy in Malignant Glioma: Novel Aspects and Mechanisms of Drug Resistance ENSG00000132646 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC11766595__F9 TLR4 inflammatory pathway ENSG00000162711 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC9700084__F1 Intranasal nerve growth factor for prevention and recovery of the outcomes of traumatic brain injury ENSG00000136869 PMC11936551__F2 LncRNA-MALAT1 acting as ceRNAs and its involvement in the EMT process of retinopathy and regulating the corresponding signaling pathway factors ENSG00000156802 ENSG00000185527 ENSG00000168036 ENSG00000112715 ENSG00000048545 ENSG00000168610 ENSG00000281857 ENSG00000136874 ENSG00000136231 PMC12023943__F4 Keratinocyte differentiation mediated by either CD9 overexpression or calcium stimulation in mouse keratinocytes ENSG00000203782 ENSG00000168036 ENSG00000010278 PMC10311025__F8 Protective effects of IRG1/itaconate on acute colitis through the inhibition of gasdermins-mediated pyroptosis and inflammation response ENSG00000278718 ENSG00000162711 ENSG00000136457 PMC3668835__F4 Genomic landscape of small intestine neuroendocrine tumors ENSG00000122025 ENSG00000066468 ENSG00000291971 ENSG00000198793 ENSG00000121879 PMC10463219__F6 Resveratrol ameliorates insulin resistance by improving insulin signaling via the DDIT4/mTOR/IRS-1/PI3K/AKT/GLUT4 pathway ENSG00000168209 ENSG00000169047 ENSG00000198793 PMC3394947__F1 The proteins involved in the different pathways related to eicosanoid biosynthesis ENSG00000167261 ENSG00000283887 ENSG00000087008 ENSG00000143198 ENSG00000148344 ENSG00000106546 ENSG00000132170 PMC5672917__F1 The role of iron in brain ageing and neurodegenerative disorders ENSG00000091972 PMC4673238__F5 Gene expression patterns through oral squamous cell carcinoma development: PD-L1 expression in primary tumor and circulating tumor cells ENSG00000110395 ENSG00000213658 ENSG00000010810 ENSG00000177606 ENSG00000113263 ENSG00000135605 PMC8293989__F1 Comparisons of Underlying Mechanisms, Clinical Efficacy and Safety Between Anti-PD-1 and Anti-PD-L1 Immunotherapy: The State-of-the-Art Review and Future Perspectives ENSG00000134982 PMC4216462__F1 TGFB signalling pathway in the early mouse embryo ENSG00000170365 ENSG00000137834 ENSG00000241186 ENSG00000156574 ENSG00000283060 ENSG00000184344 ENSG00000125968 ENSG00000148377 PMC4741283__F1 IL10/IL10R signaling pathway ENSG00000105397 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000243646 ENSG00000105639 ENSG00000175104 ENSG00000168610 ENSG00000184216 PMC3702279__F5 Schematic diagram illustrating miR-185 and ATR function in radiation response ENSG00000175054 ENSG00000164053 ENSG00000276618 PMC5691663__F1 Thyroid hormone-induced interference with resveratrol-induced antiproliferation is blocked by tetrac and its nanoparticulate analog ENSG00000171848 ENSG00000168036 ENSG00000116030 PMC5402749__F1 Necroptosis and Cancer ENSG00000137275 ENSG00000157625 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC7041258__F4 Gene expression analysis by IPA software (FC ≥ 1.5 and p value < 0.001) showing nuclear factor erythroid 2-related factor 2 (NRF2) oxidative stress response path design activated in NR8383 cells after exposure to ¼ IC50 of NM403 for 4 h ENSG00000178573 ENSG00000117707 ENSG00000079999 PMC5940740__F2 Diabetic stressors lead to Schwann cell dysfunction and neurodegeneration ENSG00000002330 ENSG00000242689 ENSG00000163914 ENSG00000139549 PMC3058235__F1 Control of GnRH secretion by growth factors and small molecules produced by glial cells ENSG00000105329 ENSG00000163235 PMC7564143__F3 Four processes model of cardiac regeneration ENSG00000099985 PMC3663490__F5 Novel Integrative Genomics Approach for Associating GWAS Information with Intrinsic Subtypes of Breast Cancer ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000144554 ENSG00000276559 ENSG00000197299 ENSG00000149554 PMC6237934__F1 PD-1 signal inhibits T-cell receptor (TCR) signaling pathway ENSG00000145604 ENSG00000291603 ENSG00000134982 ENSG00000156127 ENSG00000150907 ENSG00000198793 ENSG00000131196 PMC3663490__F6 Novel Integrative Genomics Approach for Associating GWAS Information with Intrinsic Subtypes of Breast Cancer ENSG00000188486 ENSG00000149311 ENSG00000144554 ENSG00000187790 ENSG00000187741 ENSG00000197299 ENSG00000112039 ENSG00000158169 ENSG00000095002 ENSG00000139687 ENSG00000139618 PMC7564143__F4 Simplified overview of the classic Hippo-YAP signaling pathway ENSG00000126016 ENSG00000186575 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC3638243__F8 The plasminogen (Plg)-dependent pathway of foam cell formation ENSG00000135218 ENSG00000172216 ENSG00000129226 ENSG00000122194 ENSG00000162896 PMC7862249__F1 Ubiquitin signalling in neurodegeneration: mechanisms and therapeutic opportunities ENSG00000152348 ENSG00000188554 ENSG00000123240 ENSG00000069869 ENSG00000144848 ENSG00000175104 ENSG00000145782 ENSG00000057663 ENSG00000101557 PMC6839531__F11 Schematic showing the proposed dynamic changes in the localization of LHCGR, DENND1A.V2, and RAB5B in various cellular compartments ENSG00000138039 ENSG00000111540 PMC6369476__F1 Potential proinflammatory role of resistin in the pathogenesis of osteoarthritis ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC8533869__F1 TGFB Signaling in the Pancreatic Tumor Microenvironment PMC5666889__F2 A Summary of New Findings on the Biological Effects of Selenium in Selected Animal Species—A Critical Review ENSG00000211445 ENSG00000167468 ENSG00000126432 PMC3879372__F10 Murine Gammaherpesvirus M2 Protein Induction of IRF4 via the NFAT Pathway Leads to IL-10 Expression in B Cells ENSG00000167323 ENSG00000291971 ENSG00000137265 ENSG00000197943 PMC6548059__F1 Components of the autophagy pathway reported to be deviated in neuropsychiatric disorders ENSG00000144848 PMC8458828__F6 Metabolic Reprogramming and Immune Evasion in Nasopharyngeal Carcinoma ENSG00000106546 PMC8915814__F3 Versatile Functional Energy Metabolism Platform Working From Research to Patient: An Integrated View of Cell Bioenergetics ENSG00000166278 ENSG00000062485 PMC6172368__F3 PPI network based on the interaction of the differentially expressed genes between the M2 and M0 groups ENSG00000102962 ENSG00000134594 ENSG00000187796 ENSG00000155926 ENSG00000131153 ENSG00000145386 ENSG00000104921 ENSG00000124762 ENSG00000134480 ENSG00000135838 ENSG00000137265 ENSG00000073792 ENSG00000111186 ENSG00000135929 ENSG00000027075 ENSG00000284807 ENSG00000143546 ENSG00000067057 ENSG00000128918 ENSG00000163220 ENSG00000158485 ENSG00000103569 ENSG00000058091 ENSG00000116717 ENSG00000167900 ENSG00000132170 ENSG00000146670 ENSG00000173221 ENSG00000111729 ENSG00000138135 ENSG00000158481 ENSG00000158477 ENSG00000170458 ENSG00000102970 ENSG00000172936 ENSG00000090659 PMC5790950__F1 KSHV entry by macropinocytosis and trafficking in the human microvascular dermal endothelial cells ENSG00000176108 ENSG00000291971 ENSG00000074319 ENSG00000086065 PMC6172368__F2 PPI network constructed based on the genes with differential expression between the M2 and M0 groups in the intersection of GSE18686 and GSE35449 ENSG00000187608 ENSG00000163568 ENSG00000197272 ENSG00000158517 ENSG00000205362 ENSG00000137959 ENSG00000132530 ENSG00000150782 ENSG00000168062 ENSG00000134321 ENSG00000073060 ENSG00000125144 ENSG00000143320 ENSG00000152766 ENSG00000108679 ENSG00000071967 ENSG00000124201 ENSG00000002549 ENSG00000123610 ENSG00000135929 ENSG00000130208 ENSG00000117228 ENSG00000125148 ENSG00000115267 ENSG00000185885 ENSG00000125347 ENSG00000162654 ENSG00000073756 ENSG00000276561 ENSG00000169715 ENSG00000172183 ENSG00000211445 ENSG00000169245 ENSG00000138378 ENSG00000275214 ENSG00000136960 ENSG00000187554 ENSG00000108700 ENSG00000010030 ENSG00000026751 PMC7998878__F3 TRIM8, NFKB and JAK-STAT pathways ENSG00000050730 ENSG00000111537 ENSG00000171206 ENSG00000168610 PMC4859898__F4 mTOR signaling pathway regulated by CDDO-Me in Ec109 cells ENSG00000163435 ENSG00000198793 ENSG00000173599 ENSG00000164327 PMC6172368__F5 Sub-networks constructed based on the differentially expressed genes identified in the communities of interest in the protein-protein interaction network using CFinder software ENSG00000117228 ENSG00000103569 ENSG00000109654 ENSG00000125347 ENSG00000162654 ENSG00000172183 ENSG00000168062 ENSG00000132530 ENSG00000150782 ENSG00000275214 ENSG00000111729 ENSG00000170458 ENSG00000158481 ENSG00000172936 ENSG00000002549 ENSG00000090659 PMC6235888__F6 Schematic pathway summarizing the manipulation of GAL via the activation of A7 nAChR to mediate its anti-inflammatory effect ENSG00000069482 ENSG00000173039 ENSG00000189403 PMC7247338__F3 Proposed miRNA–mRNA interaction network of the 10 most abundant differentially expressed miRNAs (DEMs) with their potential target mRNAs ENSG00000186487 ENSG00000066735 ENSG00000126775 ENSG00000136826 ENSG00000136231 ENSG00000276876 ENSG00000112242 ENSG00000134371 ENSG00000011566 ENSG00000154553 ENSG00000184384 ENSG00000180329 ENSG00000100433 ENSG00000164989 ENSG00000204335 ENSG00000083290 ENSG00000114416 ENSG00000108960 ENSG00000152601 ENSG00000100345 ENSG00000067900 ENSG00000100664 ENSG00000081189 ENSG00000127334 ENSG00000185104 ENSG00000197879 ENSG00000204217 PMC9332480__F4 Multifunctional Role of S100 Protein Family in the Immune System: An Update ENSG00000108691 ENSG00000005381 ENSG00000277943 PMC11624271__F2 General signaling pathway of CLRs from Dectin-1 and Dectin-2 clusters ENSG00000187796 ENSG00000197992 ENSG00000010671 PMC4790585__F1 Wnt/Beta-catenin canonical pathway ENSG00000087095 ENSG00000004975 ENSG00000107404 ENSG00000138795 ENSG00000100592 ENSG00000134982 ENSG00000168036 ENSG00000146122 ENSG00000161202 PMC9133079__F3 Signaling events evoked by domain III of envelop glycoprotein of tick-borne encephalitis virus and West Nile virus in human brain microvascular endothelial cells ENSG00000167601 ENSG00000171855 ENSG00000137713 ENSG00000153208 ENSG00000138378 ENSG00000092445 ENSG00000115415 ENSG00000105639 ENSG00000168610 ENSG00000142166 PMC4790585__F2 Wnt cross talk ENSG00000033327 ENSG00000002330 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC12032345__F1 STING signaling pathwayDNA from damaged mitochondria or pathogens can be recognized by cGAS, and cGAS subsequently catalyzes the formation of 2′,3′-cGAMP ENSG00000183735 ENSG00000164430 ENSG00000105612 ENSG00000197594 ENSG00000093072 PMC6771394__F6 Allelic origins of the carotenoid pathway genes PMC8099721__F1 Identification of novel targets of miR-622 in hepatocellular carcinoma reveals common regulation of cooperating genes and outlines the oncogenic role of zinc finger CCHC-type containing 11 ENSG00000140931 ENSG00000125848 ENSG00000131914 ENSG00000107443 ENSG00000168143 ENSG00000119396 ENSG00000121966 PMC6587955__F1 BMPR signaling ENSG00000121989 ENSG00000137834 ENSG00000163914 ENSG00000283060 ENSG00000204217 ENSG00000125968 ENSG00000114739 PMC3065765__F3 Iron in regulating the mTOR signaling pathway ENSG00000140992 ENSG00000168209 ENSG00000164327 PMC4539557__F9 This cartoon summarizes our observations and integrates them into the context of previous studies ENSG00000151778 ENSG00000168036 ENSG00000164690 PMC12040678__F5 Pathogenesis of HMGB1 in alopecia areata ENSG00000281324 ENSG00000189403 ENSG00000136869 PMC11853802__F2 Schematic diagram summarizing the possible involvement of the GnIH system in endocrine axes and peripheral regulation ENSG00000115138 ENSG00000145321 ENSG00000170893 PMC8238245__F1 Action of PLK inhibition ENSG00000145632 ENSG00000198793 ENSG00000142731 ENSG00000173846 PMC12001862__F9 Protective function of DHM on renal oxidative stress, inflammation, and mitochondrial-induced apoptosis by regulating the EGFR/HSP27/STAT3 signaling pathway in CP-induced AKI ENSG00000168610 ENSG00000146648 PMC9166579__F8 Human amniotic mesenchymal stem cells-derived IGFBP-3, DKK-3, and DKK-1 attenuate liver fibrosis through inhibiting hepatic stellate cell activation by blocking Wnt/Beta-catenin signaling pathway in mice ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000050165 ENSG00000168036 ENSG00000140443 PMC4207242__F1 Pathways Modulating GLI1-expression/activity in Cancer ENSG00000105329 ENSG00000138798 ENSG00000164690 ENSG00000171791 ENSG00000128602 ENSG00000146648 PMC4344387__F1 Wnt/Beta-catenin and Notch signaling pathways and pathway crosstalk as illustrated herein ENSG00000168214 ENSG00000134982 ENSG00000100744 PMC7079523__F8 Pathway and temporal expressional patterns of oil accumulation ENSG00000173599 ENSG00000198670 PMC2526691__F2 Focal adhesion pathway interaction map PMC3063577__F2 Simplified diagram showing some of the identified BCR pathway members ENSG00000095585 ENSG00000100290 ENSG00000146094 ENSG00000010810 ENSG00000198793 ENSG00000197943 ENSG00000010671 PMC6597102__F2 Blood brain barrier disruption in cerebral malaria: Beyond endothelial cell activation ENSG00000169245 ENSG00000108691 ENSG00000226275 ENSG00000170558 ENSG00000125538 ENSG00000168036 ENSG00000111321 ENSG00000164690 PMC8024566__F1 CCR7 and the reactive LN ENSG00000137077 ENSG00000186716 ENSG00000126353 PMC5727251__F4 Inhibitors of the FZD/LRP/Wnt signalling cascade ENSG00000162337 ENSG00000167941 ENSG00000185269 PMC2691779__F1 Schematic overview of the human tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) apoptosis pathway ENSG00000149311 ENSG00000168040 PMC6815304__F3 The principal signaling events occurring during fluid shear stress in bone cells ENSG00000291971 ENSG00000167941 ENSG00000170558 ENSG00000198793 ENSG00000163914 ENSG00000168036 PMC7382829__F8 Fatty acid metabolic pathways in macrophages infected with Nc-Spain1H versus non-infected cells ENSG00000182511 ENSG00000169710 ENSG00000280548 ENSG00000026103 PMC7708060__F1 Cellular pathways for DNA double-strand break repair ENSG00000143799 ENSG00000012048 ENSG00000197299 ENSG00000051180 ENSG00000310560 ENSG00000139618 PMC7382829__F6 KEGG pathway maps represent the NF-ƙB signalling pathway in which DEG in (a) bovine macrophages infected with Nc-Spain1H and (b) Nc-Spain7 versus non-infected macrophages are highlighted ENSG00000143799 ENSG00000242689 ENSG00000102871 ENSG00000111321 ENSG00000150455 ENSG00000127191 ENSG00000010671 ENSG00000142224 ENSG00000095585 ENSG00000149311 ENSG00000226275 ENSG00000213658 ENSG00000170458 ENSG00000186716 ENSG00000125538 ENSG00000136869 ENSG00000131323 ENSG00000124181 ENSG00000175104 ENSG00000121060 PMC9421435__F4 Role and Therapeutic Potential of Macropinocytosis in Cancer ENSG00000163739 ENSG00000140416 PMC10774482__F1 Canonical signaling pathways of cGAS ENSG00000183735 ENSG00000164430 PMC3247754__F3 Simplified view of the glucose sensing mechanisms in S ENSG00000196511 ENSG00000171540 ENSG00000215845 ENSG00000174840 PMC7544984__F6 Crosstalk between SRSF3 and other splicing regulators in the regulation of gene expression PMC4503753__F7 EpCAM Aptamer-siRNA Chimera Targets and Regress Epithelial Cancer ENSG00000119888 ENSG00000026508 ENSG00000168036 ENSG00000171791 PMC4979999__F6 Exercise Activates p53 and Negatively Regulates IGF-1 Pathway in Epidermis within a Skin Cancer Model ENSG00000140443 PMC5302553__F2 Efferocytosis in Atherosclerosis ENSG00000153208 PMC3833078__F3 In addition to apoptosis, AR may also regulate other kinds of cell death ENSG00000163914 ENSG00000102977 PMC9157596__F4 Clozapine Long-Term Treatment Might Reduce Epigenetic Age Through Hypomethylation of Longevity Regulatory Pathways Genes ENSG00000149212 ENSG00000169047 ENSG00000023287 ENSG00000198793 ENSG00000105647 ENSG00000141564 ENSG00000121879 ENSG00000285069 ENSG00000080546 ENSG00000175634 ENSG00000157500 ENSG00000133116 ENSG00000150907 ENSG00000171105 ENSG00000182158 ENSG00000152495 ENSG00000132356 ENSG00000107175 ENSG00000111725 ENSG00000187840 ENSG00000132170 ENSG00000181929 ENSG00000164742 ENSG00000106617 ENSG00000128272 ENSG00000174233 ENSG00000162409 ENSG00000159346 ENSG00000285070 ENSG00000171608 ENSG00000162104 PMC7401857__F10 Pro-inflammatory signaling molecules release upon HMGB1 stimulation and its receptor blocking ENSG00000189403 ENSG00000136869 PMC4043871__F2 Testosterone signaling pathways in Sertoli cells ENSG00000291971 ENSG00000146648 PMC9674421__F11 Expression and Prognostic Significance of PDIA3 in Cervical Cancer ENSG00000128272 ENSG00000150991 ENSG00000113558 ENSG00000184787 ENSG00000198168 PMC9642324__F1 Immunomodulators: still having a role? ENSG00000137364 ENSG00000136159 PMC8538681__F1 Nucleotide Pool Imbalance and Antibody Gene Diversification ENSG00000124479 ENSG00000196839 ENSG00000291814 PMC5962346__F1 Molecular targets for therapy in the HH pathway web of collaboration ENSG00000164161 ENSG00000138798 ENSG00000198793 ENSG00000198670 ENSG00000128602 ENSG00000131023 PMC8421901__F3 Underlying mechanism of sorafenib resistance in hepatocellular carcinoma: a bioinformatics study based on validated resistance-related genes ENSG00000105664 ENSG00000142192 ENSG00000133116 ENSG00000172005 ENSG00000132341 PMC8269379__F1 New Paradigm in the Relationship between Melatonin and Breast Cancer: Gut Microbiota Identified as a Potential Regulatory Agent ENSG00000106546 PMC5559174__F8 Effects of graded levels of calorie restriction: XI. Evaluation of the main hypotheses underpinning the life extension effects of CR using the hepatic transcriptome ENSG00000188554 ENSG00000163625 ENSG00000198793 ENSG00000144848 ENSG00000005893 ENSG00000284099 ENSG00000171791 ENSG00000145782 ENSG00000057663 ENSG00000136874 PMC12040678__F2 Pathogenesis of HMGB1 in vitiligo ENSG00000161921 ENSG00000189403 ENSG00000136869 PMC11959080__F2 Subcellular localization and proposed molecular mechanisms of ZNFX1 ENSG00000162711 ENSG00000088888 ENSG00000124201 PMC12040678__F3 Pathogenesis of HMGB1 in psoriasis ENSG00000162594 ENSG00000189403 ENSG00000136869 PMC5559174__F7 Effects of graded levels of calorie restriction: XI. Evaluation of the main hypotheses underpinning the life extension effects of CR using the hepatic transcriptome ENSG00000138795 ENSG00000002330 ENSG00000291971 ENSG00000169047 ENSG00000132478 ENSG00000171791 ENSG00000168040 ENSG00000196628 ENSG00000071564 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000110395 ENSG00000010810 ENSG00000163914 ENSG00000136997 ENSG00000150907 ENSG00000080839 ENSG00000026103 PMC5559174__F4 Effects of graded levels of calorie restriction: XI. Evaluation of the main hypotheses underpinning the life extension effects of CR using the hepatic transcriptome ENSG00000143799 ENSG00000167553 ENSG00000284774 ENSG00000187531 ENSG00000123416 ENSG00000073578 ENSG00000168036 ENSG00000167552 ENSG00000172795 ENSG00000142082 ENSG00000283100 ENSG00000132170 ENSG00000103479 ENSG00000139180 ENSG00000115361 ENSG00000119912 ENSG00000096717 ENSG00000089163 ENSG00000139687 ENSG00000080839 PMC3375679__F2 Environmental regulation of GSC proliferation at developmental stages of the gonad ENSG00000115977 ENSG00000180447 ENSG00000100749 ENSG00000133937 ENSG00000007171 PMC5559174__F5 Effects of graded levels of calorie restriction: XI. Evaluation of the main hypotheses underpinning the life extension effects of CR using the hepatic transcriptome ENSG00000166794 ENSG00000253293 ENSG00000171105 ENSG00000132478 ENSG00000007908 ENSG00000149311 ENSG00000291983 ENSG00000128272 ENSG00000178573 ENSG00000177606 ENSG00000197299 ENSG00000189403 ENSG00000162692 PMC5559174__F2 Effects of graded levels of calorie restriction: XI. Evaluation of the main hypotheses underpinning the life extension effects of CR using the hepatic transcriptome ENSG00000163435 ENSG00000171105 ENSG00000198793 ENSG00000163914 ENSG00000173599 ENSG00000164327 ENSG00000102104 PMC5559174__F3 Effects of graded levels of calorie restriction: XI. Evaluation of the main hypotheses underpinning the life extension effects of CR using the hepatic transcriptome ENSG00000104856 ENSG00000291603 ENSG00000102871 ENSG00000138798 ENSG00000111321 ENSG00000168040 ENSG00000150455 ENSG00000127191 ENSG00000226275 ENSG00000244687 ENSG00000163235 ENSG00000197943 ENSG00000157625 ENSG00000172936 ENSG00000175104 ENSG00000198286 PMC4790585__F7 General role of the proteins used for in silico experiments ENSG00000134982 ENSG00000168036 ENSG00000276920 PMC5487560__F1 The kynurenine pathway of tryptophan degradation ENSG00000162882 PMC8722298__F2 Small extracellular vesicles: from mediating cancer cell metastasis to therapeutic value in pancreatic cancer ENSG00000159388 ENSG00000127324 PMC4382495__F2 Signaling pathways involved in thyroid carcinogenesis and tumor progression ENSG00000002330 ENSG00000157764 ENSG00000198793 ENSG00000168036 PMC7848457__F9 Proposed model of molecular targets of NSAIDs in enhancing Hsp90 inhibitor cytotoxicity of CD44highK562 cells ENSG00000284774 ENSG00000198793 ENSG00000026508 ENSG00000168610 PMC6413549__F4 Biochemical process networks of the differentially expressed proteins generated by MetaCore™ software using a transcription regulation algorithm ENSG00000070756 ENSG00000100519 ENSG00000134308 ENSG00000117707 ENSG00000069345 ENSG00000090520 PMC6613304__F5 Nicotinamide Adenine Dinucleotide (NAD+) Biosynthetic Pathways ENSG00000077009 ENSG00000105835 ENSG00000157064 ENSG00000173614 ENSG00000008130 ENSG00000106733 PMC5802197__F3 CAD backbone network ENSG00000148926 ENSG00000142273 ENSG00000163737 ENSG00000172216 ENSG00000157227 ENSG00000167941 ENSG00000136997 ENSG00000115138 ENSG00000071051 ENSG00000164400 ENSG00000196498 ENSG00000100219 ENSG00000160293 ENSG00000118257 ENSG00000077782 ENSG00000087245 ENSG00000160182 ENSG00000145777 ENSG00000131095 ENSG00000157017 ENSG00000091879 ENSG00000132693 ENSG00000007171 ENSG00000132170 ENSG00000061938 ENSG00000063245 ENSG00000110395 ENSG00000175745 ENSG00000063660 ENSG00000163235 ENSG00000026508 ENSG00000122779 ENSG00000146648 ENSG00000115145 ENSG00000127616 ENSG00000110944 ENSG00000019991 ENSG00000198053 ENSG00000105329 ENSG00000138798 ENSG00000198793 ENSG00000099942 ENSG00000112715 ENSG00000121879 ENSG00000173702 ENSG00000127129 ENSG00000106546 ENSG00000137801 ENSG00000179295 ENSG00000277571 ENSG00000150782 ENSG00000150991 ENSG00000149968 ENSG00000128052 ENSG00000104918 ENSG00000185591 ENSG00000037280 ENSG00000128342 ENSG00000102104 ENSG00000143333 ENSG00000196233 ENSG00000196367 ENSG00000136158 ENSG00000099985 ENSG00000242689 ENSG00000162512 ENSG00000173039 ENSG00000109654 ENSG00000131910 ENSG00000160691 ENSG00000144749 ENSG00000124882 ENSG00000121351 ENSG00000177606 ENSG00000028528 ENSG00000005381 ENSG00000150630 PMC6542018__F1 Estrogen receptor (ER) activity in breast cancer - canonical (classical; ligand-mediated) and non-canonical (alternative; ligand-independent) pathways of ER activation ENSG00000066468 ENSG00000070193 ENSG00000065978 ENSG00000147862 ENSG00000140285 ENSG00000129514 ENSG00000077782 PMC8722298__F1 Small extracellular vesicles: from mediating cancer cell metastasis to therapeutic value in pancreatic cancer ENSG00000183723 ENSG00000187772 PMC12208402__F12 Proposed RasV12 singling network leading to cell dissemination ENSG00000163914 PMC3110938__F2 Genome-wide dissection of microRNA functions and co-targeting networks using gene-set signatures ENSG00000019991 ENSG00000171105 ENSG00000070831 ENSG00000146592 ENSG00000198793 ENSG00000163914 ENSG00000124126 ENSG00000196396 PMC7018661__F6 The epithelial–stromal interactions in the tumor microenvironment of GC ENSG00000169554 ENSG00000137033 ENSG00000185591 PMC4741792__F6 GLI1 orchestrates CXCR4/CXCR7 signaling to enhance migration and metastasis of breast cancer cells ENSG00000107562 ENSG00000121966 ENSG00000136167 PMC8374895__F9 miR-200a-3p Attenuates Coronary Microembolization-Induced Myocardial Injury in Rats by Inhibiting TXNIP/NLRP3-Mediated Cardiomyocyte Pyroptosis ENSG00000278718 ENSG00000162711 ENSG00000265972 PMC9408967__F9 Dentin Particulate for Bone Regeneration: An In Vitro Study ENSG00000134982 ENSG00000168036 ENSG00000163132 PMC8610981__F1 Evaluation of selected IL6/STAT3 pathway molecules and miRNA expression in chronic obstructive pulmonary disease ENSG00000168610 PMC2896914__F2 Multiple genes involved in interferon production and regulation are associated with risk for lupus ENSG00000239732 ENSG00000118503 ENSG00000175104 ENSG00000276561 PMC4405010__F1 Sessile serrated and traditional serrated pathways ENSG00000157764 ENSG00000170430 ENSG00000163453 PMC5760291__F10 Brucella abortus triggers a cGAS-independent STING pathway to induce host protection that involves guanylate-binding proteins and inflammasome activation ENSG00000164430 ENSG00000163568 ENSG00000125538 ENSG00000118520 ENSG00000007171 PMC6391709__F5 PI3K/AKT/mTOR and ERK signalling pathways associated with cardiac hypertrophy ENSG00000169047 PMC6449425__F1 Biosynthesis of isoprenoids in X ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC7367500__F1 Canonical and Non-Canonical Wnt Signaling in Immune Cells ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000134982 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC6142582__F2 Targetable molecular features of primary mediastinal large B-cell lymphoma and mediastinal gray zone lymphoma ENSG00000177455 ENSG00000162924 ENSG00000196396 PMC4725315__F5 Ingenuity pathway analysis showing up (green) and down-regulation (red) of miRNAs involved in ovarian cancer tumor samples when compared to endometriosis samples ENSG00000169032 PMC9100681__F5 Unraveling the Role of Acetic Acid Bacteria Comparing Two Acetification Profiles From Natural Raw Materials: A Quantitative Approach in Komagataeibacter europaeus ENSG00000062485 PMC4014746__F1 Canonical Wnt pathway ] ENSG00000162337 ENSG00000134982 ENSG00000165879 ENSG00000168036 PMC2739756__F1 Bile acid synthesis ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC9444450__F4 Identification of Signal Pathways and Hub Genes of Pulmonary Arterial Hypertension by Bioinformatic Analysis ENSG00000147202 ENSG00000131747 ENSG00000140285 ENSG00000111530 ENSG00000100941 ENSG00000001626 ENSG00000131477 ENSG00000096401 ENSG00000146648 ENSG00000141367 PMC3204314__F7 Signalling by vitamin A and retinol-binding protein in regulation of insulin responses and lipid homeostasis PMC5133970__F7 Schematic representation of the proposed TCS pathogenesis model PMC10093344__F1 Innate immune signaling pathway that recognizes cytosolic DNA in tumor-infiltrating dendritic cells (TIDCs) ENSG00000278718 ENSG00000164430 ENSG00000163568 PMC2739756__F3 FXR regulation of enterohepatic circulation of bile acid ENSG00000160867 PMC2739756__F4 FXR-independent and bile acid-activated cell signaling pathways in regulation of CYP7A1 transcription ENSG00000019991 ENSG00000105329 ENSG00000167910 ENSG00000125538 ENSG00000136869 ENSG00000146648 PMC10093344__F3 Tumor immunosuppressive mechanism of AIM2 in TIDCs ENSG00000278718 ENSG00000169245 ENSG00000150782 ENSG00000183735 ENSG00000164430 ENSG00000163568 PMC7813598__F9 The inhibitory effect of black radish extract (BRE) in lipopolysaccharides (LPS)-stimulated RAW 264.7 cells ENSG00000128272 ENSG00000125538 ENSG00000168610 ENSG00000079999 PMC3213687__F2 Appearance frequencies of genes in the mTOR signaling pathway ENSG00000157764 ENSG00000198793 ENSG00000164327 PMC8746472__F3 Pharmacological Effects of Grifolin: Focusing on Anticancer Mechanisms ENSG00000135446 ENSG00000171791 PMC6144698__F1 STAT3 activation pathway ENSG00000019991 ENSG00000099985 ENSG00000242689 ENSG00000163235 ENSG00000138798 ENSG00000128342 ENSG00000168610 PMC6644047__F1 Simplified TGFB signaling pathways ENSG00000135446 ENSG00000198793 ENSG00000136997 ENSG00000156574 ENSG00000123374 ENSG00000105810 PMC3943571__F1 Ras signal transduction ENSG00000198793 ENSG00000062485 PMC8797453__F5 KRAS, YWHAE, SP1 and MSRA as biomarkers in endometrial cancer ENSG00000285250 PMC8277821__F8 Schematic diagram of miR-301a-3p based signalling circuit of trastuzumab resistance in HER2-positive GC ENSG00000144749 ENSG00000077782 ENSG00000140443 PMC6584407__F7 Signaling mechanism of MUS81 and CyclinB ENSG00000149311 ENSG00000175054 ENSG00000154920 ENSG00000197299 ENSG00000051180 PMC5922678__F1 Alterations in the steroid biosynthesis pathway in congenital adrenal hyperplasia (CAH) ENSG00000203859 ENSG00000179142 ENSG00000203857 PMC9110871__F3 Viral and cellular translation during SARS‐CoV‐2 infection ENSG00000183735 ENSG00000213928 ENSG00000132661 ENSG00000115415 ENSG00000131323 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC7855940__F1 Multifunctional APE1 DNA repair–redox signaling protein as a drug target in human disease ENSG00000115008 ENSG00000132646 ENSG00000039650 ENSG00000168610 PMC9209555__F3 Targeted Sequencing Identifies the Genetic Variants Associated with High-altitude Polycythemia in the Tibetan Population ENSG00000189056 ENSG00000187266 ENSG00000100721 PMC8953329__F1 An Evaluation of CXCR4 Targeting with PAMAM Dendrimer Conjugates for Oncologic Applications ENSG00000122966 ENSG00000188158 PMC6759660__F2 Different ncRNAs regulate PDCD4 in mutiple ways ENSG00000104814 ENSG00000135446 ENSG00000168036 ENSG00000105810 PMC6896012__F1 The KEGG calcium signaling pathway ENSG00000130528 ENSG00000156026 ENSG00000186716 PMC6524680__F6 PDGF effects in periosteum derived progenitor cells and its interaction with BMP2/Smad signaling ENSG00000170365 ENSG00000134853 PMC3578923__F8 Global Analysis of the Human Pathophenotypic Similarity Gene Network Merges Disease Module Components ENSG00000117054 ENSG00000175198 ENSG00000137992 ENSG00000036473 ENSG00000128928 ENSG00000091140 PMC8742263__F2 Enhancement of Bone Regeneration Through the Converse Piezoelectric Effect, A Novel Approach for Applying Mechanical Stimulation ENSG00000170365 ENSG00000167941 ENSG00000168036 PMC7982967__F2 Mechanistic actions of Ca2+ during myofibroblast differentiation ENSG00000092439 ENSG00000137672 ENSG00000108821 ENSG00000138741 PMC4742785__F4 Working model of an integrated axon degeneration signaling cascade ENSG00000157064 ENSG00000186187 PMC5318464__F1 Diagram of immune responses induced by Leptospira sp ENSG00000162711 ENSG00000170458 ENSG00000172936 ENSG00000136869 PMC4510916__F2 Lf intervention upregulates the neurotrophin-signaling pathway in postnatal piglets ENSG00000162889 ENSG00000002330 PMC1817805__F2 AMPK and cell proliferation – AMPK as a therapeutic target for atherosclerosis and cancer ENSG00000198793 ENSG00000026103 PMC6821213__F8 FAE therapy modifies the metabolic-epigenetic interplay in multiple sclerosis to reduce pathogenic CCR6+ CD4 and CD8 T cells ENSG00000112486 PMC8699029__F1 System-Level Mechanism of Anmyungambi Decoction for Obesity: A Network Pharmacological Approach ENSG00000102871 ENSG00000198793 ENSG00000115138 ENSG00000127191 ENSG00000168610 PMC8877377__F1 High Expression of Interferon Pathway Genes CXCL10 and STAT2 Is Associated with Activated T-Cell Signature and Better Outcome of Oral Cancer Patients ENSG00000169245 PMC2878924__F6 Two models for coupling the circadian clock to the cell cycle/checkpoint response ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000136936 PMC3901112__F1 Autophagy is initiated by stimuli that activate the phosphatidylinositol 3-phosphate kinase, Vps34 ENSG00000128272 ENSG00000144895 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC2878924__F5 DNA damage checkpoint pathways ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000276618 ENSG00000113456 ENSG00000093009 PMC6039551__F3 MicroRNAs (miRNAs) regulate innate host immune response against influenza infection by targeting intracellular signaling pathways ENSG00000183735 ENSG00000088888 ENSG00000163220 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC8578384__F3 Candidate genes of SARS-CoV-2 gender susceptibility ENSG00000102145 ENSG00000239732 ENSG00000138792 ENSG00000130234 ENSG00000184012 ENSG00000145321 ENSG00000189403 ENSG00000136869 ENSG00000137845 ENSG00000277943 PMC7392272__F2 Identifying the key regulators that promote cell-cycle activity in the hearts of early neonatal pigs after myocardial injury ENSG00000004975 ENSG00000141551 ENSG00000134982 ENSG00000168036 ENSG00000170365 ENSG00000186575 ENSG00000136997 ENSG00000129474 ENSG00000166167 ENSG00000107404 ENSG00000197905 ENSG00000139926 ENSG00000114978 ENSG00000153303 ENSG00000007866 ENSG00000018408 ENSG00000150457 ENSG00000081051 ENSG00000144791 ENSG00000072803 ENSG00000131023 ENSG00000291420 ENSG00000074219 ENSG00000068028 ENSG00000143514 ENSG00000115266 ENSG00000019549 ENSG00000161202 ENSG00000168646 ENSG00000169435 PMC9204329__F1 Of DEK proto-oncogene as a prognostic biomarker for colorectal cancer: An evidence-based review ENSG00000168036 ENSG00000124795 PMC5372848__F1 Activation of the RAS/ERK and phosphoinositide cell signaling pathways following the binding of cell survival signals to receptor tyrosine kinases (RTK) PMC8508836__F7 Survival Motor Neuron Gene Expression by Calcium Signaling ENSG00000042832 ENSG00000152495 ENSG00000111786 PMC2805009__F1 Cross-talk between TCR and TGFB signaling networks ENSG00000134460 ENSG00000177606 ENSG00000049768 PMC3445581__F2 Transcriptional Differences between Rhesus Embryonic Stem Cells Generated from In Vitro and In Vivo Derived Embryos ENSG00000159167 ENSG00000107562 ENSG00000136997 ENSG00000185591 ENSG00000112715 ENSG00000168610 PMC9442310__F7 miRNAs‐mediated control of MOV10 expression regulates L1 retrotransposition in mESCs ENSG00000128191 ENSG00000113360 ENSG00000155363 PMC6283569__F6 E4orf1: A protein for enhancing glucose uptake despite impaired proximal insulin signaling ENSG00000169047 PMC2928541__F2 Wnt signaling pathway ENSG00000134982 ENSG00000168036 ENSG00000105723 PMC11016262__F2 Intestinal Mucosal Immune Barrier: A Powerful Firewall Against Severe Acute Pancreatitis-Associated Acute Lung Injury via the Gut-Lung Axis ENSG00000167207 ENSG00000106100 PMC11899224__F10 Effect of BBR on NLRP3 inflammasome pathway and TLR7/NFKB pathway ENSG00000278718 ENSG00000162711 ENSG00000125538 ENSG00000172936 PMC11016262__F3 Immune cells along the gut-lung axis ENSG00000099866 ENSG00000137033 ENSG00000166090 PMC8151866__F1 BANK1 in B Cell Signaling and Disease ENSG00000291971 ENSG00000186716 ENSG00000153064 ENSG00000172936 ENSG00000083799 ENSG00000175104 ENSG00000276561 PMC5101451__F1 Signaling pathways of TLRs ENSG00000183735 ENSG00000239732 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC5506042__F6 Number of genes including those downstream of HIF-1 signaling pathway were up-regulated in the pancreas in response to HFD ENSG00000100234 ENSG00000167772 ENSG00000157150 ENSG00000128052 ENSG00000154059 ENSG00000171791 ENSG00000124212 ENSG00000124762 ENSG00000135919 PMC6988017__F3 PPI network analysis ENSG00000051523 ENSG00000164932 ENSG00000011600 ENSG00000186517 ENSG00000110799 ENSG00000136826 ENSG00000029559 ENSG00000011422 ENSG00000150907 ENSG00000277263 ENSG00000154096 ENSG00000121310 ENSG00000099204 ENSG00000143878 ENSG00000112562 ENSG00000284984 ENSG00000019582 ENSG00000138193 ENSG00000158714 ENSG00000161921 ENSG00000118785 ENSG00000170458 ENSG00000015285 ENSG00000100985 ENSG00000198734 ENSG00000162692 ENSG00000152952 ENSG00000100365 PMC7300300__F3 Schematic illustration of the intervened network with Gegen Qinlian Decoction (GQD) based on ingenuity pathway analysis (IPA) ENSG00000109819 ENSG00000117054 ENSG00000198380 ENSG00000288174 ENSG00000161533 ENSG00000151365 ENSG00000115361 ENSG00000076555 ENSG00000132170 PMC3004666__F1 Cetuximab in the treatment of colorectal cancer ENSG00000002330 ENSG00000138798 ENSG00000198793 ENSG00000140443 PMC7332664__F1 Cores of the HIF pathway and the Hippo pathway ENSG00000134086 ENSG00000150457 ENSG00000131023 PMC8617980__F1 Current Adenosinergic Therapies: What Do Cancer Cells Stand to Gain and Lose? ENSG00000156110 ENSG00000196839 ENSG00000291814 PMC8617980__F2 Current Adenosinergic Therapies: What Do Cancer Cells Stand to Gain and Lose? PMC8617980__F3 Current Adenosinergic Therapies: What Do Cancer Cells Stand to Gain and Lose? ENSG00000275331 ENSG00000185818 ENSG00000010671 PMC4159007__F8 Epigenetics and the Evolution of Darwin’s Finches ENSG00000175193 ENSG00000170458 ENSG00000168040 ENSG00000150455 ENSG00000143387 PMC5429547__F3 Differentiation of naïve Th cells into Th2 cells ENSG00000137033 ENSG00000163599 ENSG00000107485 ENSG00000166090 PMC4159007__F9 Epigenetics and the Evolution of Darwin’s Finches ENSG00000168036 ENSG00000080166 PMC10981339__F3 Anti-inflammatory effects of SIRT in IVDD ENSG00000101945 ENSG00000173039 ENSG00000136869 ENSG00000077463 ENSG00000096717 PMC4159007__F7 Epigenetics and the Evolution of Darwin’s Finches ENSG00000111537 ENSG00000113558 ENSG00000134363 PMC10187169__F2 Pathways included in the model ENSG00000134086 ENSG00000291971 ENSG00000114315 PMC4306671__F3 Pathway enrichment results: (A) hsa05200 (pathway in cancer); (B) hsa05218 (melanoma) ENSG00000157404 ENSG00000002330 ENSG00000157764 ENSG00000205221 ENSG00000135446 PMC11808223__F1 Intestinal changes in T2DM ENSG00000111537 ENSG00000125538 ENSG00000172936 ENSG00000131096 PMC5384647__F10 An ID2-dependent mechanism for VHL inactivation in cancer ENSG00000134086 PMC8297547__F1 Protein Kinase R in Bacterial Infections: Friend or Foe? ENSG00000162711 ENSG00000128272 ENSG00000144895 ENSG00000163568 ENSG00000125538 ENSG00000091592 ENSG00000091106 ENSG00000168040 PMC8463317__F4 lncRNA and breast cancer: Progress from identifying mechanisms to challenges and opportunities of clinical treatment ENSG00000088305 ENSG00000198793 ENSG00000123374 ENSG00000172936 ENSG00000105810 PMC7835797__F1 Epigenetic Alterations in Renal Cell Cancer With TKIs Resistance: From Mechanisms to Clinical Applications ENSG00000167601 ENSG00000115828 ENSG00000019991 ENSG00000169554 ENSG00000198793 ENSG00000168036 ENSG00000143499 PMC8422929__F1 Regulators of liver cancer stem cells ENSG00000019991 ENSG00000164938 ENSG00000135111 ENSG00000181555 ENSG00000168610 ENSG00000136826 PMC8832957__F2 Tumorigenic bacteria in colorectal cancer: mechanisms and treatments ENSG00000163961 ENSG00000051180 ENSG00000136869 PMC5332411__F3 IFN pathway of elephant shark ENSG00000120833 ENSG00000213928 ENSG00000140968 ENSG00000033800 ENSG00000137265 ENSG00000168310 ENSG00000180008 ENSG00000276561 PMC3747328__F1 The role of K+ channels during cell cycle progression and proliferation ENSG00000175938 ENSG00000144935 ENSG00000293604 ENSG00000135446 ENSG00000177606 ENSG00000165125 ENSG00000158887 ENSG00000123374 ENSG00000132478 PMC6144355__F1 Molecular mechanisms of TNBC ENSG00000167601 ENSG00000157557 ENSG00000134982 ENSG00000198793 ENSG00000136997 ENSG00000168036 ENSG00000146648 PMC6202827__F7 IL-1B signaling pathway in CXCR3-mediated MSC transendothelial migration ENSG00000178860 ENSG00000186810 ENSG00000125538 ENSG00000138755 PMC4779832__F4 Cross talk between ROS and Keap1-Nrf2-ARE signaling pathway ENSG00000010810 ENSG00000285246 ENSG00000105227 PMC4779832__F2 Cross talk between ROS and NFKB signaling pathway ENSG00000104856 ENSG00000173039 ENSG00000285246 PMC4779832__F3 Cross talk between ROS and MAPKs signaling pathway ENSG00000115415 ENSG00000291761 ENSG00000081189 PMC5971010__F1 Admixture Mapping Links RACGAP1 Regulation to Prostate Cancer in African Americans ENSG00000198435 ENSG00000137845 PMC8999833__F3 Candidate Genes and Pathways in Rice Co-Responding to Drought and Salt Identified by gcHap Network ENSG00000173805 ENSG00000148926 PMC7404102__F1 SARS-CoV(-2) host cell infection, replication (Phase I) and induction of immune response (Phase II) ENSG00000134982 ENSG00000130234 ENSG00000184012 PMC6888566__F1 Wnt signal transduction ENSG00000281324 ENSG00000162337 ENSG00000134569 ENSG00000134982 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC7284145__F7 Biological pathway related to TMPRSS2 predicted by KEGG ENSG00000157554 ENSG00000166145 ENSG00000115590 ENSG00000244405 ENSG00000175832 ENSG00000184012 ENSG00000104368 PMC9368248__F6 Molecular Regulation of Yak Preadipocyte Differentiation and Proliferation by LncFAM200B and ceRNA Regulatory Network Analysis ENSG00000273529 ENSG00000133961 ENSG00000114315 ENSG00000140464 ENSG00000117399 PMC196255__F1A Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway ENSG00000169047 ENSG00000198793 ENSG00000133124 PMC6888566__F4 Roles of non-canonical Wnt pathways in osteoclast differentiation and function ENSG00000162552 ENSG00000169071 ENSG00000164935 ENSG00000163914 ENSG00000177606 ENSG00000146122 ENSG00000185591 ENSG00000002745 ENSG00000160447 ENSG00000131196 PMC5751354__F4A Metabolic Pathways of the Warburg Effect in Health and Disease: Perspectives of Choice, Chain or Chance PMC6032409__F3 Signaling pathway that results in the production of tumor necrosis factor alpha (TNFA) in macrophages after the stimulation by lead and lipopolysaccharide (LPS) ENSG00000170458 ENSG00000172936 ENSG00000136869 PMC5786553__F1 Fatty acid synthesis in Mortierella alpina ENSG00000149485 PMC4942776__F6 Profiling of Host Cell Response to Successive Canine Parvovirus Infection Based on Kinetic Proteomic Change Identification ENSG00000142230 ENSG00000159461 ENSG00000001626 ENSG00000188612 PMC4916003__F1 Natural products as TLR agonists and antagonists affecting various stages in the signaling pathway, including downstream molecules MyD88 and IKK ENSG00000174125 ENSG00000239732 ENSG00000136869 ENSG00000175104 PMC7278058__F6 Pathway modeling ENSG00000134982 ENSG00000173039 ENSG00000141744 ENSG00000168036 ENSG00000122786 ENSG00000158517 ENSG00000241644 ENSG00000171791 ENSG00000127191 ENSG00000169245 ENSG00000100290 ENSG00000166813 ENSG00000164690 ENSG00000128602 PMC3939471__F1 Involvement of CD81 in Hepatitis C Virus (HCV) lifecycle ENSG00000130164 ENSG00000015520 ENSG00000110651 ENSG00000135404 ENSG00000146648 PMC7107758__F4 Resistance mechanisms to BRAF and MEK inhibitors in BRAF-V600E melanoma ENSG00000019991 ENSG00000138798 ENSG00000198793 ENSG00000196712 PMC7104317__F1 Development of Drugs Based on High-Polymeric Double-Stranded RNA for Antiviral and Antitumor Therapy ENSG00000150782 ENSG00000157625 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC6613635__F1 Simplified rationale for performing studies in NHP sepsis models of antibody inhibition of TNFA and IL-6 ENSG00000117525 ENSG00000134982 ENSG00000136869 ENSG00000122194 PMC4026009__F3 Network-Based Kernel Machine Test for the Identification of Risk Pathways in Genome-Wide Association Studies ENSG00000170608 ENSG00000262785 ENSG00000002330 ENSG00000157764 ENSG00000135100 ENSG00000169856 ENSG00000182759 ENSG00000122859 ENSG00000124762 ENSG00000106331 ENSG00000121351 ENSG00000135446 ENSG00000139515 ENSG00000114315 ENSG00000139687 PMC7999907__F1 Degradation of p53 induced by E6 variants of human papillomavirus (HPV) 16 favors metabolic reprogramming ENSG00000171105 ENSG00000078237 ENSG00000159399 PMC3249681__F8 Simplified diagram depicting the proposed signaling pathway of the CB1 activation that inhibits the activity of small GTPase RhoA to inhibit motility of PC-3 cells ENSG00000070831 PMC7999907__F3 Metabolic reprogramming is mediated by HPV 16 E6 variants through c-Myc, hypoxia-inducible factor (HIF)-1A, WNT, and miR-21 ENSG00000134086 ENSG00000135218 ENSG00000134982 ENSG00000169710 ENSG00000168036 ENSG00000168610 PMC7466715__F3 Signaling pathways of TGFB and Wnt involved in joint pathophysiology ENSG00000170365 ENSG00000162337 ENSG00000168036 PMC5943339__F3 Top networks of differentially expressed genes in PTvs.N as identified by Ingenuity Pathway Analysis show strong association to cancer and connective tissue disorders ENSG00000171195 ENSG00000140519 ENSG00000007306 ENSG00000163209 ENSG00000113140 ENSG00000140297 ENSG00000135373 ENSG00000282891 ENSG00000095585 ENSG00000117525 ENSG00000119514 ENSG00000133110 ENSG00000134827 ENSG00000149968 ENSG00000137573 ENSG00000117983 PMC5943339__F4 Top networks of differentially expressed genes in Mvs.PT as identified by Ingenuity Pathway Analysis show strong association to cancer and connective tissue disorders ENSG00000105722 ENSG00000173011 ENSG00000134762 ENSG00000144331 ENSG00000140968 ENSG00000127528 ENSG00000169032 ENSG00000134900 ENSG00000245848 ENSG00000144579 ENSG00000163171 ENSG00000102879 ENSG00000167880 ENSG00000136997 ENSG00000132698 ENSG00000187758 ENSG00000178773 ENSG00000075218 ENSG00000140743 PMC6059749__F11 miR-142-5p regulates CD4+ T cells in human non-small cell lung cancer (NSCLC) through PD-L1 expression via the PTEN pathway ENSG00000159128 ENSG00000027697 PMC7868342__F11 Signaling pathways involved in rhFGF20-mediated protection against BBB disruption both in vivo in TBI mice and an in vitro in a TNF-Alpha-induced HBMEC model ENSG00000125538 PMC3849582__F1 Network Diagram of the single C ENSG00000103569 ENSG00000149273 PMC8467361__F2 Diabetes Mellitus and Periodontitis Share Intracellular Disorders as the Main Meeting Point ENSG00000177169 ENSG00000198793 ENSG00000096717 PMC6336830__F3 Summary of the mechanisms involved in the stimulation of brown adipogenesis, mitochondrial biogenesis and energy expenditure by some dietary molecules ENSG00000142611 ENSG00000196689 PMC6184651__F7 ECM-receptor interaction pathway, (b) focal adhesion pathway, (c) regulation of actin cytoskeleton pathway, (d) TGFB signaling pathway PMC8582887__F2 PI3KD Inhibitors as Immunomodulatory Agents for the Treatment of Lymphoma Patients ENSG00000111537 ENSG00000150907 ENSG00000188404 ENSG00000126353 ENSG00000112182 ENSG00000049768 PMC9156734__F3 Roles of different molecules related to the PI3K/AKT pathway in CECs in diseases and therapeutic strategies ENSG00000019991 ENSG00000291971 ENSG00000138798 ENSG00000112561 ENSG00000189403 ENSG00000096717 ENSG00000140443 PMC9156734__F4 Localization and function of different molecules involved in the PI3K/AKT signalling pathway in the CE ENSG00000019991 PMC7643595__F1 Revisiting the Bacterial Phylum Composition in Metabolic Diseases Focused on Host Energy Metabolism ENSG00000131096 PMC9156734__F2 PI3K/AKT signalling pathway in CECs ENSG00000171105 ENSG00000002330 ENSG00000291971 ENSG00000288145 ENSG00000138798 ENSG00000132646 ENSG00000136997 ENSG00000196689 ENSG00000089159 ENSG00000140443 PMC4931961__F3 TNFA Regulates Endothelial Progenitor Cell Migration via CADM1 and NF-kB ENSG00000183735 ENSG00000023734 ENSG00000110514 ENSG00000102871 ENSG00000168040 ENSG00000145088 PMC12080927__F6 Distribution of targets in the MAPK signaling pathway ENSG00000087095 ENSG00000170458 ENSG00000138798 ENSG00000130159 ENSG00000127191 ENSG00000081189 ENSG00000026103 PMC3692130__F1 Graphical representation of Wnt pathway as described in the KEGG repository () ENSG00000087095 ENSG00000107404 ENSG00000156076 ENSG00000178585 ENSG00000137673 ENSG00000105656 ENSG00000196470 ENSG00000182621 ENSG00000072803 ENSG00000140807 ENSG00000163904 ENSG00000116161 ENSG00000164736 ENSG00000101849 ENSG00000100387 ENSG00000147869 ENSG00000177606 ENSG00000136997 ENSG00000102312 ENSG00000168772 PMC6423135__F5 Pathway scheme with marked involved proteins ENSG00000169291 ENSG00000002330 ENSG00000177606 ENSG00000175104 ENSG00000181026 PMC3198763__F2 MTORC1 pathway controls cellular metabolism ENSG00000131473 ENSG00000110921 ENSG00000149084 ENSG00000112972 ENSG00000067057 ENSG00000113161 ENSG00000169710 ENSG00000074800 ENSG00000134824 ENSG00000153982 ENSG00000115419 ENSG00000159399 ENSG00000169299 ENSG00000123983 PMC8958887__F7 M6A writers regulated by the IL-6/STAT3 inflammatory pathway facilitate cancer cell stemness in cholangiocarcinoma ENSG00000145388 ENSG00000168036 ENSG00000073792 ENSG00000146457 ENSG00000168610 ENSG00000165819 ENSG00000110693 PMC5125896__F1 Biosynthesis, remodeling and turnover of mitochondrial cardiolipin ENSG00000087157 ENSG00000198670 ENSG00000184207 PMC8541410__F2 An Update on Innate Immune Responses during SARS-CoV-2 Infection ENSG00000162711 ENSG00000213928 ENSG00000276561 ENSG00000142166 ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC11757636__F3 Influence of autophagy on the progression of pneumoconiosis ENSG00000130749 ENSG00000198793 ENSG00000136869 ENSG00000026103 PMC11757636__F4 Influences of apoptosis and pyroptosis on the progression of pneumoconiosis ENSG00000278718 ENSG00000162711 ENSG00000144895 ENSG00000026103 PMC9571513__F7 Gastrodin Ameliorates Cognitive Dysfunction in Vascular Dementia Rats by Suppressing Ferroptosis via the Regulation of the Nrf2/Keap1-GPx4 Signaling Pathway ENSG00000167468 ENSG00000079999 PMC8748174__F1 Roles, molecular mechanisms, and signaling pathways of TMEMs in neurological diseases ENSG00000135446 ENSG00000132646 ENSG00000123374 ENSG00000171791 ENSG00000162692 PMC8000702__F4 C-Peptide as a Therapy for Type 1 Diabetes Mellitus ENSG00000110799 ENSG00000125538 PMC4933106__F1 Role of reactive oxygen species in age‐related neuromuscular deficits ENSG00000284774 ENSG00000105227 PMC2881367__F7 CircleMap display of the ErbB2 pathway ENSG00000065361 ENSG00000198793 ENSG00000158458 PMC4500525__F1 Mammalian inositol phosphate metabolism ENSG00000274958 PMC8136122__F7 TGFB1: Gentlemanly orchestrator in idiopathic pulmonary fibrosis (Review) ENSG00000026103 PMC6562018__F2 Reduction in AAs (EAAs, BCAAs, and Met) induces uncharged tRNA and activates GCN2, eIF2A and ATF4/5, resulting in increased FGF21 production ENSG00000128272 PMC7533008__F4 Underlying glucometabolic mechanisms on pyruvate protection against diabetic nephropathy PMC7076852__F7 Summary diagram of the proposed mechanisms underlying protective effects of C3G against glutamate-induced oxidative/ER stress apoptosis in HT22 cells ENSG00000105656 PMC2964046__F1 Currently-known relationships among genes analyzed based on manually curated examination of the published literature within the Ingenuity Pathway Analysis® Knowledge Base ENSG00000197747 ENSG00000151726 ENSG00000135218 ENSG00000105329 ENSG00000181104 ENSG00000198793 ENSG00000186480 ENSG00000171209 ENSG00000169710 ENSG00000118777 ENSG00000158125 ENSG00000109861 ENSG00000126247 ENSG00000136997 ENSG00000285482 ENSG00000131473 ENSG00000087245 ENSG00000070404 ENSG00000151365 ENSG00000099194 ENSG00000062282 ENSG00000132170 ENSG00000149485 ENSG00000070770 ENSG00000124155 ENSG00000198911 ENSG00000115461 PMC5514720__F2 Transcriptomic analysis of HBCs reveals that the Notch pathway is differentially regulated during activation from dormancy ENSG00000128917 ENSG00000148400 ENSG00000074181 ENSG00000133961 ENSG00000184916 ENSG00000090932 PMC7474159__F9 New concept based on this study ENSG00000134853 PMC7027016__F4 Histone methylation plays a role in hypertension, aortic dissection, and pulmonary arterial hypertension ENSG00000057663 PMC8224166__F1 Microbial dysbiosis in carcinogenesis & cancer therapies ENSG00000168036 PMC3399249__F2 Interactions between cytokine and glucocorticoid receptor (GR) signaling pathways ENSG00000105397 ENSG00000115415 ENSG00000168610 PMC9356167__F6 Dietary supplementation of salidroside alleviates liver lipid metabolism disorder and inflammatory response to promote hepatocyte regeneration via PI3K/AKT/Gsk3B pathway ENSG00000042832 ENSG00000125538 PMC9007519__F6 Integrated Network Pharmacology and Experimental Verification to Explore the Molecular Mechanism of Hedysarum Multijugum Maxim–Curcumae Rhizoma Herb Pair for Treating Non-Small Cell Lung Cancer ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000169047 ENSG00000104894 PMC4040986__F2 An Expanded Genomic Representation of the Phylum Cyanobacteria ENSG00000039537 ENSG00000156110 ENSG00000062485 PMC4673013__F1 MicroRNA interactome in metabolic homeostasis ENSG00000164938 PMC7027016__F7 Histone methyltransferases and demethylases are involved in tumor angiogenesis ENSG00000102145 ENSG00000087245 ENSG00000183576 ENSG00000104885 ENSG00000112715 PMC5217345__F3 Fibroblast growth factor 21 (FGF21) regulates Sirt 1-mediated release of adiponectin from adipose tissue with relevance to NAFLD and the metabolic syndrome ENSG00000096088 ENSG00000096717 PMC7995212__F2 ACE2 in the second act of COVID‐19 syndrome: Peptide dysregulation and possible correction with oestrogen ENSG00000130234 PMC9407429__F6 microRNA Expression Profile of Purified Alveolar Epithelial Type II Cells ENSG00000037965 ENSG00000133937 ENSG00000183072 ENSG00000135503 ENSG00000175104 ENSG00000204217 PMC8306954__F2 Cell Death in Coronavirus Infections: Uncovering Its Role during COVID-19 ENSG00000162711 ENSG00000130234 ENSG00000131323 ENSG00000168404 PMC5406035__F5 RIPK3 interacts with MAVS to regulate type I IFN-mediated immunity to Influenza A virus infection ENSG00000088888 ENSG00000137275 ENSG00000285379 PMC9105267__F1 CXCR4/CXCL12 Activities in the Tumor Microenvironment and Implications for Tumor Immunotherapy ENSG00000107562 ENSG00000291603 ENSG00000198053 ENSG00000134982 ENSG00000124126 ENSG00000144476 ENSG00000121966 PMC8841526__F8 Identification of Key Genes Related With Aspartic Acid Metabolism and Corresponding Protein Expression in Human Colon Cancer With Postoperative Prognosis and the Underlying Molecular Pathways Prediction ENSG00000245848 ENSG00000243709 ENSG00000197408 ENSG00000070669 ENSG00000125968 PMC6018060__F2 Macrophage Phenotype in Regulating the Response to Radiation Therapy ENSG00000107485 ENSG00000168610 PMC8645898__F2 SOX9: Advances in Gynecological Malignancies ENSG00000125398 ENSG00000159399 PMC7186467__F1 Targeting mitochondria for the treatment of Parkinson’s disease (PD) ENSG00000117118 ENSG00000158828 PMC10573925__F1 Effect of sclerostin on the Wnt/Beta-catenin pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6113920__F1 The human adrenal cortex: growth control and disorders ENSG00000140691 ENSG00000185231 ENSG00000010310 PMC9574006__F2 Immune checkpoints in cardiovascular disease ENSG00000089692 ENSG00000111537 ENSG00000104760 ENSG00000168610 PMC9495572__F1 Harnessing the Therapeutic Potential of the Nrf2/Bach1 Signaling Pathway in Parkinson’s Disease ENSG00000178573 ENSG00000156273 ENSG00000079999 PMC3919531__F1 The Intertwined Roles of Transcription and Repair Proteins ENSG00000012061 ENSG00000188486 ENSG00000154920 ENSG00000188827 ENSG00000139618 ENSG00000149311 ENSG00000175054 ENSG00000292191 ENSG00000144554 ENSG00000132646 ENSG00000139372 ENSG00000051180 ENSG00000136936 PMC7611290__F3 REV7: Jack of many trades ENSG00000134982 ENSG00000159263 ENSG00000253251 ENSG00000122705 ENSG00000122376 ENSG00000106628 ENSG00000117399 ENSG00000196628 ENSG00000132341 PMC3481134__F7 PRb/E2F signaling pathway mediates three distinct arms of TGFB tumor-suppressive effects ENSG00000205250 ENSG00000164305 PMC12028493__F12 Proposed mechanism underlying the anti-PD effect of epicoccin A ENSG00000109819 ENSG00000123416 ENSG00000198793 ENSG00000158828 ENSG00000145782 ENSG00000132356 ENSG00000285069 PMC6100359__F1 Insulin signalling pathway activated in retina and RB ENSG00000171105 ENSG00000002330 ENSG00000110395 ENSG00000198793 ENSG00000132478 ENSG00000026103 PMC6932876__F1 Mechanisms of ADSCs differentiation into SMC and EC PMC2704234__F3 Immune activation induced by Beta-glucans ENSG00000187796 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC5400562__F8 Imidazoline I2 receptor inhibitor idazoxan regulates the progression of hepatic fibrosis via Akt-Nrf2-Smad2/3 signaling pathway ENSG00000181019 PMC5790215__F1 Prediction of reaction knockouts to maximize succinate production by Actinobacillus succinogenes ENSG00000122966 ENSG00000172005 PMC7767220__F4 Roles of MMPs and TIMPs in the pathogenesis of human inflammatory diseases ENSG00000100234 ENSG00000125538 ENSG00000198793 PMC9180633__F1 Gamma Secretase Inhibitors as Potential Therapeutic Targets for Notch Signaling in Uterine Leiomyosarcoma ENSG00000168214 ENSG00000198435 ENSG00000114315 ENSG00000137845 PMC5741248__F10 Restoration of type 1 iodothyronine deiodinase expression in renal cancer cells downregulates oncoproteins and affects key metabolic pathways as well as anti-oxidative system ENSG00000157827 ENSG00000171903 ENSG00000105835 ENSG00000151632 ENSG00000153317 ENSG00000095383 ENSG00000168610 ENSG00000187134 ENSG00000019582 ENSG00000077420 ENSG00000123609 ENSG00000198074 ENSG00000152465 PMC5831796__F1 Hedgehog signaling pathway ENSG00000180447 ENSG00000106571 ENSG00000144857 ENSG00000128602 PMC7190864__F4 Comparison of significant canonical pathways and upstream regulators in monocytes infected or non-infected with Mtb UT127 and UT205 isolates ENSG00000170909 ENSG00000170458 ENSG00000102245 ENSG00000163914 ENSG00000122877 ENSG00000189403 ENSG00000136869 ENSG00000163497 ENSG00000163737 ENSG00000073756 ENSG00000110876 ENSG00000062485 PMC12068291__F2 Graphical representation of normal functioning of Notch signaling pathway and its importance in controlling cellular and developmental processes ENSG00000281324 ENSG00000042832 ENSG00000162337 ENSG00000134982 ENSG00000128602 ENSG00000118971 PMC7190864__F5 Death Receptor Signaling pathway is illustrating inhibition of apoptosis in monocytes infected with Mtb ENSG00000160789 ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000111348 ENSG00000115317 ENSG00000026103 PMC11356816__F9 Interactions between BAs and Other Viruses ENSG00000256762 ENSG00000136869 PMC5831796__F4 GLI1-expressing hair follicle stem cells and their roles ENSG00000174059 PMC5794649__F2 FoxOs related signaling pathway in cancer progression and metastasis ENSG00000169554 ENSG00000002330 ENSG00000118515 ENSG00000123374 ENSG00000121966 ENSG00000283100 PMC5110612__F1 Proteins with known or inferred roles in autophagy that underlie muscle pathologies in mice and humans ENSG00000160789 ENSG00000188554 ENSG00000171100 ENSG00000005893 ENSG00000165280 ENSG00000152137 ENSG00000151929 ENSG00000171791 ENSG00000145782 ENSG00000160131 ENSG00000057663 PMC7327642__F8 Mechanism underlying Notch ability to promote drug resistance in multiple myeloma (MM) microenvironment ENSG00000105656 ENSG00000171791 ENSG00000114315 ENSG00000121966 PMC3116873__F1 Oncogenic CagA Promotes Gastric Cancer Risk via Activating ERK Signaling Pathways: A Nested Case-Control Study ENSG00000291971 ENSG00000099942 PMC3649461__F1 Signal transduction pathways of the amino acid (AA) response (AAR) ENSG00000128272 ENSG00000144895 PMC9114642__F1 Endoplasmic Reticulum Stress and the Unfolded Protein Response in Cerebral Ischemia/Reperfusion Injury ENSG00000128272 ENSG00000144895 ENSG00000171791 ENSG00000127191 PMC9114642__F2 Endoplasmic Reticulum Stress and the Unfolded Protein Response in Cerebral Ischemia/Reperfusion Injury ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC3540836__F1 Experimentally supported and inferred factors of Drosophila triacylglycerol synthesis and mobilization at lipid storage droplets ENSG00000166819 ENSG00000042832 ENSG00000173599 PMC7585053__F3 Graphical representation of the five candidate pathways and their significantly contributing genes ENSG00000101367 ENSG00000131462 ENSG00000160299 ENSG00000060982 ENSG00000011376 ENSG00000176101 ENSG00000166851 ENSG00000115207 ENSG00000119041 ENSG00000292191 ENSG00000163882 ENSG00000067704 ENSG00000234032 ENSG00000114107 ENSG00000204843 ENSG00000274803 ENSG00000105552 ENSG00000170027 ENSG00000161203 ENSG00000182923 ENSG00000042753 ENSG00000013503 ENSG00000100664 ENSG00000105568 ENSG00000131828 ENSG00000107295 ENSG00000196961 ENSG00000117650 ENSG00000183020 ENSG00000122705 ENSG00000142731 ENSG00000141367 PMC5356785__F1 ΔNp63A and microRNAs: leveraging the epithelial-mesenchymal transition ENSG00000198793 ENSG00000168036 PMC9025012__F2 Implications of Sphingolipid Metabolites in Kidney Diseases ENSG00000100422 ENSG00000166224 ENSG00000119537 ENSG00000102172 PMC7049903__F5 Angiotensin peptide synthesis and cyclic nucleotide modulation in sympathetic stellate ganglia ENSG00000130234 PMC3093412__F1 Viperin Links Lipid Bodies To Immune Defense ENSG00000239732 ENSG00000172936 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC9594894__F9 B3GALT4 remodels the tumor microenvironment through GD2-mediated lipid raft formation and the c-met/AKT/mTOR/IRF-1 axis in neuroblastoma ENSG00000169245 ENSG00000198793 ENSG00000138755 ENSG00000125347 PMC3386270__F8 IL-4 Engagement of the Type I IL-4 Receptor Complex Enhances Mouse Eosinophil Migration to Eotaxin-1 In Vitro ENSG00000070831 ENSG00000291971 ENSG00000183625 ENSG00000163914 PMC3116400__F1 DSBs in S and G2 phases of the cell cycle, collapsed replication forks, and daughter-strand gaps all require HR for their repair ENSG00000012048 ENSG00000083093 ENSG00000051180 ENSG00000139618 PMC3712126__F2 Bcl-2 family-regulated pathway and phenotypes in Bcl-2 knockout mice after status epilepticus ENSG00000002330 ENSG00000104081 PMC7674659__F4 Mitochondrial carnitine shuttle, one-carbon folate metabolism and trans-sulfuration pathway ENSG00000284320 ENSG00000157184 ENSG00000144659 ENSG00000100714 ENSG00000164466 ENSG00000079432 ENSG00000163738 ENSG00000164933 ENSG00000178445 ENSG00000026103 PMC4229513__F3 Outline of the targeted therapies, which are currently available or under development for the treatment of hepatocellular carcinoma, and the molecular targets on which they are believed to act upon ENSG00000002330 ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC1952644__F1 Alternative signaling: cardiomyocyte B1-adrenergic receptors signal through EGFRs ENSG00000291971 ENSG00000113070 ENSG00000146648 PMC2751538__F7 Proposed VEGF-C/D cell signaling pathway to transduce LAM cell proliferation ENSG00000198793 ENSG00000150630 PMC4614397__F1 Feedback regulation of PI3K/Akt/mTORC1 signaling by Grb10 ENSG00000106070 ENSG00000198793 PMC5976638__F3 The purinosome—a naturally occurring enzyme cluster? a Protein–protein interactions within the purinosome ENSG00000128050 PMC6733417__F2 Inflammation and renal fibrosis: recent developments on key signaling molecules as potential therapeutic targets ENSG00000019991 ENSG00000198793 ENSG00000163884 PMC506920__F6 Changes in transcripts associated with the DNA synthesis pathway ENSG00000094804 ENSG00000115942 ENSG00000123374 ENSG00000093009 PMC8319838__F3 Temozolomide resistance in glioblastoma - a comprehensive review ENSG00000002330 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8319838__F4 Temozolomide resistance in glioblastoma - a comprehensive review ENSG00000087095 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC8761945__F3 Emerging Role of Rho Guanine Nucleotide Exchange Factors in Cardiovascular Disorders: Insights Into Atherosclerosis: A Mini Review ENSG00000274726 ENSG00000116641 ENSG00000160145 ENSG00000128512 ENSG00000076928 ENSG00000102606 ENSG00000126217 ENSG00000070831 ENSG00000163914 PMC8319838__F5 Temozolomide resistance in glioblastoma - a comprehensive review ENSG00000149311 ENSG00000177169 ENSG00000198793 ENSG00000100219 ENSG00000168610 PMC4002322__F1 AMPK-p53-mTOR pathway in metabolic adaptation ENSG00000136048 PMC11079312__F8 Proposed lipogenic pathway regulated by MUL1 during conditions of HFD ENSG00000090432 ENSG00000169710 ENSG00000004779 PMC4002322__F2 p53 regulation of energy metabolism ENSG00000135423 ENSG00000078237 ENSG00000284194 ENSG00000159399 PMC7073173__F2 BMP signaling pathways ENSG00000198793 PMC5339410__F6 JAK-STAT and chemokine signaling pathwaysA ENSG00000108691 ENSG00000159128 ENSG00000213928 ENSG00000147168 ENSG00000291971 ENSG00000173757 ENSG00000105639 ENSG00000100485 ENSG00000168610 PMC8508623__F1 Signaling Enzymes and Ion Channels Being Modulated by the Actin Cytoskeleton at the Plasma Membrane ENSG00000171105 PMC7874141__F1 Hypothetical model to illustrate activation of the complement system, inflammation and coagulation following SARS-CoV-2 infection ENSG00000166278 PMC9569742__F1 Antiaging Activities of Phytochemicals in Dark-Colored Plant Foods: Involvement of the Autophagy- and Apoptosis-Associated Pathways ENSG00000123395 ENSG00000126775 ENSG00000144848 ENSG00000112561 ENSG00000145782 ENSG00000057663 PMC6726207__F1 Small molecules enhance knock-in efficiency ENSG00000149311 ENSG00000051180 ENSG00000102104 ENSG00000139618 PMC6441195__F3 Exo-circRNAs play a crucial role via their sponging function and can be secreted into body fluid in tumors ENSG00000142611 ENSG00000183742 ENSG00000145386 PMC7996181__F9 Mechanosensing by the nucleus ENSG00000160789 ENSG00000291971 PMC7996181__F8 Hippo pathway and the role of YAP and TAZ in mechanotransduction of SC activity ENSG00000126016 ENSG00000186575 ENSG00000163914 ENSG00000197905 ENSG00000198670 ENSG00000007866 ENSG00000150457 ENSG00000132849 ENSG00000131023 ENSG00000074219 PMC3951857__F1 Wnt/Beta-catenin signaling pathway ENSG00000162337 ENSG00000134982 ENSG00000167941 PMC2649571__F7 Beta-Catenin-Dependent Wnt Pathway Mediates Anteroposterior Axon Guidance in Motor Neurons ENSG00000134982 ENSG00000168036 PMC6589846__F1 Schematic illustration of the interleukin (IL)-12/IL-23 pathway ENSG00000162594 ENSG00000096996 ENSG00000138378 ENSG00000105397 ENSG00000168610 PMC5484415__F7 From Krebs to Clinic: Glutamine Metabolism to Cancer Therapy ENSG00000198793 ENSG00000136997 ENSG00000115419 PMC3185594__F8 Signaling pathways involved in JSRV Env-induced cell transformation ENSG00000291971 ENSG00000198793 ENSG00000136869 ENSG00000068001 PMC8126205__F6 Immunomodulatory Effects of Vitamin D Supplementation in a Deficient Population ENSG00000104365 ENSG00000170458 ENSG00000269335 ENSG00000136869 ENSG00000142089 PMC2291100__F1 Proposed biosynthetic pathway of Tcm PKS and a comparison of hypothetical intermediates for two possible folding pathways ENSG00000180210 ENSG00000100473 PMC5294827__F4 Sexual dimorphism in the axonal signaling pathway ENSG00000164050 ENSG00000070831 ENSG00000172602 ENSG00000150093 ENSG00000064300 PMC4991391__F4 N-glycans in colorectal cancer progression: potential biomarkers and therapeutic applications ENSG00000152127 ENSG00000138798 ENSG00000146648 PMC10619560__F4 Biosynthetic pathway of caproic acid and other organic acids in C. butyricum GD1-1 PMC5484415__F3 From Krebs to Clinic: Glutamine Metabolism to Cancer Therapy ENSG00000135069 ENSG00000070669 ENSG00000115419 ENSG00000167701 PMC5484415__F4 From Krebs to Clinic: Glutamine Metabolism to Cancer Therapy ENSG00000147162 ENSG00000128272 ENSG00000144895 ENSG00000115419 PMC5484415__F5 From Krebs to Clinic: Glutamine Metabolism to Cancer Therapy ENSG00000125166 ENSG00000065833 PMC4991391__F1 N-glycans in colorectal cancer progression: potential biomarkers and therapeutic applications ENSG00000157764 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000171791 ENSG00000146648 PMC5484415__F6 From Krebs to Clinic: Glutamine Metabolism to Cancer Therapy ENSG00000177058 ENSG00000143761 ENSG00000198793 ENSG00000115419 PMC5434854__F5 Top ranking gene network by gScore from the gene list uploaded from the SSRI versus control analysis ENSG00000019991 ENSG00000070831 ENSG00000156299 ENSG00000010810 ENSG00000185591 ENSG00000096264 PMC2801866__F3 Thrombospondin-1 (TSP1) binds to two receptors on endothelial cells that inhibit NO signaling ENSG00000135218 ENSG00000291971 ENSG00000010810 PMC5434854__F6 Most significant canonical pathway from the gene list obtained from the esciptalpram versus control analysis ENSG00000188486 ENSG00000164053 ENSG00000124614 ENSG00000131165 ENSG00000188582 ENSG00000140259 ENSG00000167968 ENSG00000163812 ENSG00000276876 ENSG00000012048 ENSG00000175054 ENSG00000198740 ENSG00000008988 ENSG00000125398 ENSG00000162607 ENSG00000167972 ENSG00000163728 ENSG00000186187 PMC2801866__F4 NO/cGMP pathway is a signaling node for pro- and anti-angiogenic signaling ENSG00000135218 ENSG00000291971 ENSG00000010810 PMC2435382__F11 Hypothetical scheme illustrates the putative intracellular signaling cascades serving as the context for the data collected in the current study PMC7502477__F3 Chemical Structure and Biosynthesis of NAD+ ENSG00000105835 ENSG00000278488 PMC7212029__F6 Wnt negative regulation in ligand-dependent (LD) and ligand-independent (LI) tumours ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000108375 ENSG00000185269 ENSG00000140807 PMC4684266__F1 Simplified scheme of sulfur metabolism with an emphasis on the H2S-generating reactions PMC2801866__F1 VEGF binding to VEGFR2 on endothelial cells activates its Tyr kinase activity and results in autophosphorylation of the receptor at several cytoplasmic sites ENSG00000107338 ENSG00000291971 PMC8117458__F7 Neuropathies and neurological dysfunction induced by coronaviruses ENSG00000130234 PMC4489419__F1 Speculative model of FGF23 gene transcriptional regulation ENSG00000152266 ENSG00000154342 ENSG00000168036 ENSG00000077782 PMC3407651__F1 STAT3 signalling pathway in ALK+ ALCL ENSG00000134460 ENSG00000213658 ENSG00000105639 ENSG00000168610 PMC10474093__F9 Working model ENSG00000102962 ENSG00000102970 PMC9139536__F3 Novel T Follicular Helper-like T-Cell Lymphoma Therapies: From Preclinical Evaluation to Clinical Reality ENSG00000178078 ENSG00000213658 ENSG00000134982 ENSG00000113263 ENSG00000124181 ENSG00000141968 PMC8733955__F2 Metabolism of invading and circulating (detached) cancer cells ENSG00000154342 ENSG00000135423 ENSG00000172497 ENSG00000291971 ENSG00000113140 ENSG00000173599 ENSG00000288335 ENSG00000110931 ENSG00000124766 ENSG00000169710 ENSG00000070669 ENSG00000150630 PMC8733955__F3 Metabolism of cancer cells colonizing in distant organs ENSG00000135218 ENSG00000092621 ENSG00000291971 ENSG00000173599 ENSG00000170145 ENSG00000169710 ENSG00000100033 PMC8035038__F8 Potential molecular mechanism of anticancer effects of SLT on ovarian cancer ENSG00000135446 ENSG00000170558 PMC8998816__F2 FTO m6A Demethylase in Obesity and Cancer: Implications and Underlying Molecular Mechanisms ENSG00000012061 ENSG00000245848 ENSG00000198492 ENSG00000099326 ENSG00000100146 ENSG00000188389 ENSG00000121966 ENSG00000278693 PMC7603193__F1 Interactions between non-coding RNAs and the TGFB signaling pathway in hereditary hemorrhagic telangiectasia (HHT) ENSG00000170365 ENSG00000128191 ENSG00000113360 PMC3407651__F2 MEK/ERK signalling pathway in ALK+ ALCL ENSG00000198793 PMC3407651__F3 PI3K/Akt signalling pathway in ALK+ ALCL ENSG00000198793 ENSG00000164690 ENSG00000128602 ENSG00000118971 PMC12243992__F2 Palmitoylation of EGFR, VEGFR, ER and GP130 ENSG00000163812 ENSG00000146648 ENSG00000177054 PMC9520191__F10 Polysaccharide from Atractylodes macrocephala Koidz binding with zinc oxide nanoparticles: Characterization, immunological effect and mechanism ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC5148674__F3 The p53 tumor suppressor in metabolism and diabetes ENSG00000135423 ENSG00000096088 ENSG00000166592 PMC2844217__F1 Schematic representation of the biosynthetic pathway of emetine, cephaeline, and related alkaloidal glucosides in P ENSG00000151376 ENSG00000065833 ENSG00000082212 PMC5378285__F8 A hypothetical mechanism for the anti‐tumor effects of verteporfin in pancreatic ductal adenocarcinoma (PDAC) cells ENSG00000087245 PMC3772385__F8 Model describing the relationship of osteoblast-produced Bmp2 and connections to VegfA production and increased microvascularization that serves as a major niche for mesenchymal stem cells ENSG00000178860 ENSG00000112715 ENSG00000108821 PMC5155150__F6 Bulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cells ENSG00000243709 ENSG00000147869 ENSG00000104332 PMC11818554__F7 Pathway regulating MSC osteogenic differentiation ENSG00000152266 ENSG00000128272 ENSG00000168036 ENSG00000128602 PMC11818554__F2 Wnt Signaling in MSC osteogenesis ENSG00000178860 ENSG00000124256 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000163914 ENSG00000173599 ENSG00000177606 ENSG00000168036 ENSG00000277641 ENSG00000125084 PMC6905465__F2 DNA damage response pathway ENSG00000149311 ENSG00000175054 ENSG00000051180 ENSG00000112039 PMC4007761__F2 Secretory pathway components studied in zebrafish and implicated in human diseases ENSG00000168538 ENSG00000152700 ENSG00000138674 ENSG00000167632 ENSG00000176986 PMC2905230__F1 Simplified Overview of TLR Signaling ENSG00000170458 ENSG00000136869 ENSG00000276561 ENSG00000184216 PMC8141582__F7 Synergistic Effect of Statins and Abiraterone Acetate on the Growth Inhibition of Neuroblastoma via Targeting Androgen Receptor ENSG00000160752 ENSG00000198793 ENSG00000113161 PMC4887533__F1 Overview of the ferroptosis pathway ENSG00000135423 ENSG00000072274 PMC7037253__F1 IL-10 production is metabolically regulated ENSG00000198793 ENSG00000117335 ENSG00000136869 ENSG00000096717 ENSG00000168610 ENSG00000106546 PMC7037253__F2 Anti-inflammatory response initiated downstream of the IL-10R ENSG00000019991 ENSG00000168209 ENSG00000128016 ENSG00000099985 ENSG00000165030 ENSG00000110324 ENSG00000168610 ENSG00000142224 ENSG00000278788 ENSG00000117036 ENSG00000105397 ENSG00000115415 ENSG00000128342 ENSG00000162892 PMC2756670__F3 Potential mechanisms of estrogen-mediated signaling through estrogen receptor (ESR) and G protein-coupled receptor 30 (GPR30) ENSG00000291971 ENSG00000113070 ENSG00000146648 PMC2756670__F4 The proposed model underlying the potential lithogenic mechanisms of estrogen through the estrogen receptor 1 (ESR1) pathway in the liver ENSG00000005471 ENSG00000138075 ENSG00000073734 ENSG00000143921 PMC4307189__F2 Network view of (A) 104, (B) 188, and (C) 299 putative drug-resistant cross-talks between pathways using Reactome, KEGG, and WikiPathway pathway databases in Breast Cancer Cell-line: SKBR3 (GSE38376) ENSG00000157404 ENSG00000163914 ENSG00000136997 ENSG00000128602 ENSG00000146648 ENSG00000087460 ENSG00000178568 PMC3035754__F1 Regulatory network governing mitochondrial functions orchestrated by PGC-1A ENSG00000134086 ENSG00000096717 PMC9495868__F4 Suppressing the PI3K/AKT Pathway by miR-30d-5p Mimic Sensitizes Ovarian Cancer Cells to Cell Death Induced by High-Dose Estrogen ENSG00000143799 ENSG00000110330 ENSG00000063322 ENSG00000187608 ENSG00000134308 ENSG00000089157 ENSG00000108654 ENSG00000170365 ENSG00000168283 ENSG00000134086 ENSG00000183735 ENSG00000105325 ENSG00000159216 ENSG00000136997 ENSG00000105810 ENSG00000184900 ENSG00000140443 ENSG00000023445 ENSG00000166167 ENSG00000142192 ENSG00000170027 ENSG00000110107 ENSG00000148400 ENSG00000197102 ENSG00000100345 ENSG00000150459 ENSG00000136603 ENSG00000069869 ENSG00000121481 ENSG00000132646 ENSG00000196363 ENSG00000182481 ENSG00000109332 ENSG00000196504 ENSG00000137818 ENSG00000109606 ENSG00000095015 ENSG00000196470 ENSG00000166266 ENSG00000043093 ENSG00000135341 ENSG00000164305 ENSG00000074800 ENSG00000134419 ENSG00000168310 ENSG00000122565 ENSG00000215301 ENSG00000253729 ENSG00000100811 ENSG00000108055 ENSG00000064393 ENSG00000153201 ENSG00000131508 ENSG00000170142 ENSG00000162924 ENSG00000143933 ENSG00000173226 ENSG00000186298 ENSG00000115875 ENSG00000070756 ENSG00000149311 ENSG00000176986 ENSG00000072401 ENSG00000177606 ENSG00000048052 ENSG00000115232 ENSG00000141367 PMC4503552__F1 Endocannabinoid system giving rise to endocannabinoids (2AG and AEA) and arachidonic acid and subsequently synthesis of prostaglandin glycerol esters, prostanoids, and prostamides ENSG00000117480 ENSG00000095303 ENSG00000073756 PMC12014746__F4 Impacts of sulfate polysaccharide JCS1S2 on retinal neovascularization in oxygen-induced retinopathy rats ENSG00000136869 ENSG00000112715 PMC9599575__F3 Glycation-Associated Diabetic Nephropathy and the Role of Long Noncoding RNAs ENSG00000138798 ENSG00000125538 ENSG00000096717 PMC12131810__F5 Signaling pathways for axonal regeneration within neurons ENSG00000198793 ENSG00000158828 ENSG00000110931 ENSG00000101298 ENSG00000168610 PMC3882535__F3 Novel GPCR-based signaling mechanisms in ASM ENSG00000117152 ENSG00000182621 PMC8478603__F1 Natural Killer T (NKT) Cells and Periodontitis: Potential Regulatory Role of NKT10 Cells PMC4478640__F8 Model for negative feedback loop by which the ARGOS family desensitizes ethylene signaling ENSG00000143867 ENSG00000164920 PMC7407804__F1 Signaling events downstream of EphA activation by ephrin-As ENSG00000134215 ENSG00000160293 PMC3408193__F9 Proposed protective pathway by E-LP against glutamate-induced apoptosis in RGCs ENSG00000175899 ENSG00000124181 PMC5404978__F10 Proposed model for FoxO1 and AMPK regulation of EtOH-induced autophagy ENSG00000177169 ENSG00000110497 ENSG00000126775 ENSG00000284099 PMC9027827__F3 Advances in the development of new biomarkers for Alzheimer’s disease ENSG00000132906 ENSG00000291983 ENSG00000198793 ENSG00000168040 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC8788185__F3 Molecular mechanism of therapeutic approaches for human gastric cancer stem cells ENSG00000168036 ENSG00000128602 ENSG00000168610 PMC9675776__F9 GediNET for discovering gene associations across diseases using knowledge based machine learning approach ENSG00000149311 ENSG00000138798 ENSG00000136997 ENSG00000164327 ENSG00000213341 ENSG00000112715 ENSG00000118257 ENSG00000158125 ENSG00000163631 PMC316360__F6 Interphase/S phase omission between the two meiotic divisions ENSG00000172680 ENSG00000276876 PMC5663306__F1 Bile acid metabolism and signaling in liver disease and therapy ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC6563994__F6 Social status regulates the hepatic miRNAome in rainbow trout: Implications for posttranscriptional regulation of metabolic pathways ENSG00000067057 ENSG00000135845 ENSG00000197616 ENSG00000131828 ENSG00000113742 ENSG00000074800 ENSG00000128272 ENSG00000173599 ENSG00000182255 ENSG00000124253 ENSG00000176358 ENSG00000132275 ENSG00000152556 ENSG00000060762 PMC9180999__F4 PQBP1: The Key to Intellectual Disability, Neurodegenerative Diseases, and Innate Immunity ENSG00000164430 PMC5434854__F1 Top ranking gene network by P‐value from the gene list uploaded from the NRI versus Control analysis ENSG00000149273 ENSG00000147133 ENSG00000158796 ENSG00000132964 ENSG00000107175 ENSG00000123268 ENSG00000172201 PMC5434854__F2 Top ranking gene network by gScore from the gene list uploaded from the NRI versus control analysis ENSG00000139574 ENSG00000169006 ENSG00000182687 ENSG00000150991 ENSG00000115993 ENSG00000164128 ENSG00000101188 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000182606 PMC5434854__F3 Association between the gene list and known processes pathways reveals a role for Glucocorticoids ENSG00000004478 ENSG00000100906 ENSG00000116030 ENSG00000155974 PMC5434854__F4 Top ranking gene network by P‐value from the gene list uploaded from SSRI versus control group analysis ENSG00000047410 ENSG00000134982 ENSG00000080819 ENSG00000139496 ENSG00000278224 ENSG00000108828 ENSG00000188582 ENSG00000138386 ENSG00000132182 ENSG00000196313 ENSG00000137221 ENSG00000117399 ENSG00000063177 ENSG00000142541 ENSG00000166685 PMC4073101__F3 Cilia and cilia-associated proteins in cancer ENSG00000019991 ENSG00000087245 ENSG00000134086 ENSG00000169071 ENSG00000111859 ENSG00000163235 ENSG00000291971 ENSG00000198793 ENSG00000087586 ENSG00000168610 ENSG00000146648 PMC6944116__F5 Protein interaction and functional clustering of identified hits and known UV‐G2 checkpoint components ENSG00000143799 ENSG00000160789 ENSG00000221914 ENSG00000159388 ENSG00000165280 ENSG00000120539 ENSG00000175054 ENSG00000182247 ENSG00000132383 ENSG00000061337 ENSG00000051180 ENSG00000130513 ENSG00000128989 ENSG00000143420 ENSG00000105568 ENSG00000168610 ENSG00000174307 ENSG00000145604 ENSG00000134574 ENSG00000135446 ENSG00000177606 ENSG00000132646 ENSG00000165392 ENSG00000167986 ENSG00000070950 ENSG00000127616 PMC4802403__F1 The mTOR pathway, it's classical upstream inputs and downstream targets.mTOR exists as two separate signalling complexes which are structurally distinct ENSG00000106070 ENSG00000169047 ENSG00000198793 ENSG00000145979 ENSG00000155792 ENSG00000164327 ENSG00000146648 PMC8617565__F4 Proteome Analysis of the Hypothalamic Arcuate Nucleus in Chronic High-Fat Diet-Induced Obesity ENSG00000002330 ENSG00000148082 PMC7961974__F8 Pathway activation patterns of the NOTCH pathway in the different CD-groups ENSG00000005339 ENSG00000248329 ENSG00000133961 ENSG00000106003 PMC11466965__F6 Signaling pathway of HO-1 in the protection of diabetic nephropathy ENSG00000162711 ENSG00000167468 PMC4876232__F1 FGF21 induces preventive effect on CVDs through multiple signaling pathways ENSG00000002330 ENSG00000105550 ENSG00000096717 PMC11466965__F4 HO-1 may be involved in diabetic cardiomyopathy by regulating various signaling pathways ENSG00000162711 ENSG00000167468 PMC6410037__F2 Telomere length maintenance mechanisms ENSG00000178971 ENSG00000257949 ENSG00000132646 ENSG00000164362 ENSG00000107960 ENSG00000051180 ENSG00000077514 PMC7842273__F1 Two major arginine metabolic pathways: NO synthesis vs ENSG00000081181 ENSG00000118520 ENSG00000036473 ENSG00000123505 PMC6364748__F2 Oncogenic and tumor suppressive signaling involving Dmp1 and Arf ENSG00000100811 ENSG00000149311 ENSG00000168283 ENSG00000121068 ENSG00000122691 ENSG00000135446 ENSG00000177606 ENSG00000136997 ENSG00000135111 PMC2753833__F4 Transition to endocycles in Drosophila ENSG00000094804 ENSG00000134982 PMC9363567__F3 Macrophages: A communication network linking Porphyromonas gingivalis infection and associated systemic diseases ENSG00000170458 PMC4698487__F2 Perspective on targeting copper metabolism for the treatment of hepatocellular carcinoma ENSG00000173992 ENSG00000138495 ENSG00000123191 ENSG00000177556 PMC3702256__F1 Pathview: an R/Bioconductor package for pathway-based data integration and visualization ENSG00000145604 ENSG00000149311 ENSG00000108055 ENSG00000073111 ENSG00000112742 ENSG00000093009 PMC4320984__F8 Activation of Beta-catenin Signaling by TFF1 Loss Promotes Cell Proliferation and Gastric Tumorigenesis ENSG00000160182 ENSG00000168036 PMC1369209__F3 Models for ECT-2 activation and its role in activating the EGFR/RAS/MAPK pathway ENSG00000114346 ENSG00000138798 ENSG00000146648 PMC5392598__F4 Schematic overview of the sex development gene regulation network ENSG00000162552 ENSG00000169218 ENSG00000143355 ENSG00000125398 ENSG00000168036 ENSG00000102678 PMC11906670__F2 Biosynthesis pathways and receptors of AA-derived eicosanoids and their influence on cDC migration ENSG00000226275 ENSG00000126353 PMC11906670__F3 S1P synthesis and influence on cDC migration ENSG00000063176 ENSG00000137077 ENSG00000126353 ENSG00000170989 ENSG00000180739 ENSG00000213694 ENSG00000125910 ENSG00000267534 PMC10136533__F2 Regulatory network of OTUD5 in immune response and DNA damage repair ENSG00000183735 ENSG00000164430 ENSG00000149136 ENSG00000104517 ENSG00000172936 ENSG00000131323 ENSG00000105185 ENSG00000276561 PMC8804138__F3 Single nucleotide variants of receptor for advanced glycation end-products (AGER) gene: is it a new opening in the risk assessment of diabetic retinopathy?—a review ENSG00000189403 ENSG00000198670 ENSG00000166278 PMC10136533__F3 OTUD5 is involved in the development of cancer (see also Table 1) ENSG00000198793 ENSG00000155792 ENSG00000292211 ENSG00000121807 ENSG00000105185 ENSG00000178828 ENSG00000121060 ENSG00000140464 PMC9208207__F5 Transcriptional changes in the peripheral blood leukocytes from Brangus cattle before and after tick challenge with Rhipicephalus australis ENSG00000102871 ENSG00000155313 ENSG00000163702 ENSG00000150782 ENSG00000183735 ENSG00000172216 ENSG00000066044 ENSG00000149968 ENSG00000263528 ENSG00000082512 ENSG00000125538 ENSG00000108688 ENSG00000113520 ENSG00000164400 ENSG00000157625 ENSG00000056736 ENSG00000064012 ENSG00000148346 ENSG00000100906 ENSG00000108342 ENSG00000173039 ENSG00000168040 ENSG00000127191 ENSG00000177663 ENSG00000073756 ENSG00000076604 ENSG00000108691 ENSG00000111537 ENSG00000102970 ENSG00000131323 ENSG00000100985 ENSG00000175104 ENSG00000115009 PMC4624682__F5 Proposed model illustrating the multiple signaling pathways by which PGRN (Atsttrin as well) exerts its anti-inflammatory actions ENSG00000102871 ENSG00000049768 ENSG00000127191 PMC11906670__F4 Biosynthesis and role of 7A,25-OHC in cDC localization within secondary lymphoid organs ENSG00000138135 ENSG00000137077 ENSG00000126353 PMC11788143__F2 Signalling pathways in pancreatic and peripancreatic cells whose abnormalities cause diabetes of the young at maturity (MODY) ENSG00000006071 ENSG00000198793 ENSG00000139515 ENSG00000159346 ENSG00000185002 ENSG00000106331 PMC7326080__F2 TNF induced cell death signaling ENSG00000102871 ENSG00000189403 ENSG00000168040 ENSG00000168404 ENSG00000127191 PMC7326080__F1 TNF induced canonical NFKB pathway ENSG00000102871 ENSG00000173039 ENSG00000157625 ENSG00000083799 ENSG00000154124 ENSG00000127191 PMC8508208__F1 Cancer Cell Death: Therapeutic Implications for Pancreatic Ductal Adenocarcinoma ENSG00000125166 ENSG00000065833 PMC8794746__F1 New Insights into LINC00346 and its Role in Disease ENSG00000134057 ENSG00000136997 ENSG00000172005 ENSG00000168036 ENSG00000065268 ENSG00000168610 PMC6354878__F4 Signaling pathway and GO analyses were performed to identify the biological functions of the subsets of differentially expressed genes after BP5 treatment ENSG00000134982 PMC8794746__F2 New Insights into LINC00346 and its Role in Disease ENSG00000197343 ENSG00000131503 ENSG00000291379 PMC6089846__F3 Rubone and the p53 pathway ENSG00000138795 ENSG00000026508 ENSG00000168036 PMC8508208__F4 Cancer Cell Death: Therapeutic Implications for Pancreatic Ductal Adenocarcinoma ENSG00000187608 ENSG00000099985 ENSG00000105329 ENSG00000198793 ENSG00000156574 ENSG00000164690 PMC8490884__F10 Neurodevelopmental Disorders in Patients With Complex Phenotypes and Potential Complex Genetic Basis Involving Non-Coding Genes, and Double CNVs ENSG00000140157 ENSG00000292354 ENSG00000100439 ENSG00000068383 ENSG00000137656 ENSG00000288461 PMC4740183__F3 Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease ENSG00000164904 ENSG00000118520 ENSG00000036473 ENSG00000132840 ENSG00000016391 PMC5844108__F10 Different metabolic responses in acquiring FK866 resistance in CEM RES (a) and MDA RES (b) cells ENSG00000105835 ENSG00000278488 PMC6089846__F5 Relationship between AR translocation and the AKT signaling pathway ENSG00000198793 ENSG00000177606 PMC3565434__F8 Schematic diagram of proposed CD44-regulated signaling pathway ENSG00000010810 ENSG00000026508 PMC7322178__F5 Metabolic impact of tyrosine kinase inhibitor (TKI) administration ENSG00000198793 ENSG00000166278 ENSG00000146648 PMC4611193__F2 The regulation of intestinal iron transport ENSG00000010704 PMC5540723__F3 VEGF/VEGFR signaling and the approved therapeutic agents targeting this signaling ENSG00000112715 ENSG00000150630 PMC4882508__F1 Pathway Compartmentalization in Peroxisome of Saccharomyces cerevisiae to Produce Versatile Medium Chain Fatty Alcohols ENSG00000288217 ENSG00000166278 PMC5540723__F1 PD-1 pathway signaling and the targeting of the PD-1 pathway during cancer immunotherapy ENSG00000134982 PMC4531352__F3 Maize Primary Metabolic Network Involving Key Genes and Metabolites Identified in This Study.Metabolites that were not identified in this study are shown in purple ENSG00000005882 ENSG00000151914 ENSG00000128928 ENSG00000062485 PMC7492291__F1 Apoptotic signaling pathways triggered in CD4+CD8+ double positive (DP) thymocytes during T ENSG00000145321 ENSG00000113494 ENSG00000026103 PMC6894428__F3 Simplified model of the molecular evolution of each colorectal cancer subtype ENSG00000165556 ENSG00000157764 ENSG00000134982 PMC5287404__F4 Roles of malyl-CoA/Beta-methylmalyl-CoA lyases and malyl-CoA lyase/thioesterases (red) in different acetate assimilation pathways: the methylaspartate cycle in H ENSG00000065833 ENSG00000082212 PMC4023931__F3 Digital Expression Profiling Identifies RUNX2, CDC5L, MDM2, RECQL4, and CDK4 as Potential Predictive Biomarkers for Neo-Adjuvant Chemotherapy Response in Paediatric Osteosarcoma ENSG00000105472 ENSG00000151835 ENSG00000113140 ENSG00000197565 ENSG00000150457 ENSG00000186716 ENSG00000136997 ENSG00000163554 ENSG00000054118 ENSG00000111786 ENSG00000139687 ENSG00000026103 ENSG00000204941 PMC8375225__F7 Discovery and Validation of Nitroxoline as a Novel STAT3 Inhibitor in Drug-resistant Urothelial Bladder Cancer ENSG00000135446 ENSG00000121058 ENSG00000168610 PMC4833098__F3 Canonical PPAR signaling pathway ENSG00000157184 ENSG00000150991 ENSG00000100979 ENSG00000165269 ENSG00000102977 PMC4083752__F1 Unexpected targets and triggers of autoimmunity ENSG00000162594 ENSG00000150907 ENSG00000118515 PMC8838632__F2 Alkaloids and Colon Cancer: Molecular Mechanisms and Therapeutic Implications for Cell Cycle Arrest ENSG00000177169 ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000120868 ENSG00000105810 ENSG00000171791 PMC3019561__F2 Mitochondria and the synthesis of phospholipids ENSG00000163624 ENSG00000173599 ENSG00000184207 PMC5489807__F3 Levels of crosstalk between the HIF and the NFKB pathways ENSG00000173120 ENSG00000173039 PMC7609840__F1 Relevant JAK-STAT signaling pathways in the pathogenesis of Spondyloarthritis ENSG00000162594 ENSG00000096996 ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000105639 ENSG00000168610 PMC5489807__F1 Activation pathways for canonical and non-canonical NFKB signalling ENSG00000104856 ENSG00000173039 ENSG00000157625 ENSG00000111321 ENSG00000168040 ENSG00000127191 PMC11598946__F3 Cytosolic sensing of BRSV by RIG-I, MDA-5, and NOD2 ENSG00000088888 ENSG00000167207 ENSG00000175104 PMC11598946__F5 Some of the respiratory syncytial virus’s immune-evading mechanisms ENSG00000088888 ENSG00000167207 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC9354928__F2 Research Progress on the Regulation Mechanism of Key Signal Pathways Affecting the Prognosis of Glioma ENSG00000198793 PMC8704013__F1 Arginine and Arginases Modulate Metabolism, Tumor Microenvironment and Prostate Cancer Progression ENSG00000108691 ENSG00000113520 PMC9354928__F3 Research Progress on the Regulation Mechanism of Key Signal Pathways Affecting the Prognosis of Glioma ENSG00000177169 ENSG00000083290 ENSG00000167965 PMC8704013__F2 Arginine and Arginases Modulate Metabolism, Tumor Microenvironment and Prostate Cancer Progression ENSG00000081181 ENSG00000108691 ENSG00000138798 ENSG00000198793 ENSG00000113520 ENSG00000121807 PMC8616477__F2 Melanoma Targeted Therapies beyond BRAF-Mutant Melanoma: Potential Druggable Mutations and Novel Treatment Approaches ENSG00000002330 ENSG00000157764 ENSG00000135446 ENSG00000198793 ENSG00000171791 PMC10820115__F3 Canonic polyamine biosynthetic pathway of mammals (hosts of trypanosomatids) ENSG00000288145 ENSG00000128513 PMC7606114__F4 Lysosome and pyroptosis ENSG00000278718 ENSG00000162711 PMC6851521__F2 The molecular mechanisms of LncRNA-correlated PKM2 in cancer metabolism ENSG00000198793 ENSG00000144848 ENSG00000168036 PMC4941807__F5 Schematic illustration of the coagulation pathway and its inhibitor systems ENSG00000019991 ENSG00000003436 ENSG00000196975 ENSG00000138772 ENSG00000175899 ENSG00000115718 ENSG00000178726 ENSG00000184500 PMC7887310__F1 IFN action on cellular metabolism pathways ENSG00000138135 ENSG00000026103 PMC4941807__F4 Ingenuity pathway analysis revealed hepatocyte growth factor (HGF) as an upstream regulator ENSG00000019991 ENSG00000138772 ENSG00000175899 ENSG00000168610 ENSG00000178726 PMC6379038__F2 Cholinergic signaling via nAChRs and muscarinic acetylcholine receptors (mAChRs) regulates striatal function ENSG00000168610 PMC5016220__F1 Critical role of the sphingolipid pathway in stroke: a review of current utility and potential therapeutic targets ENSG00000100422 ENSG00000197471 ENSG00000170989 ENSG00000180739 ENSG00000172057 ENSG00000213694 ENSG00000125910 ENSG00000267534 ENSG00000183018 ENSG00000102172 PMC5016220__F2 Critical role of the sphingolipid pathway in stroke: a review of current utility and potential therapeutic targets ENSG00000163914 ENSG00000170989 ENSG00000213694 ENSG00000125910 ENSG00000267534 PMC6851521__F1 Molecular mechanisms of LncRNA-correlated PKM2 in cancer metabolism ENSG00000198793 ENSG00000168610 PMC5584221__F9 EETs reduces LPS-induced hyperpermeability by targeting GRP78 mediated Src activation and subsequent Rho/ROCK signaling pathway ENSG00000291971 ENSG00000168036 PMC7770114__F7 Chronic administration of l-DOPA leads to a sensitization of D1 receptors, which maintain the over-activation of PKA in LIDs ENSG00000125740 ENSG00000117480 ENSG00000196689 PMC4315049__F2 Secretion of FABP4 in association with lipolysis ENSG00000169047 ENSG00000145321 ENSG00000165269 PMC8750774__F2 Metabolic Implications of Immune Checkpoint Proteins in Cancer ENSG00000182511 PMC8957101__F1 Hidden One: What We Know About Bitter Taste Receptor 39 ENSG00000185933 ENSG00000183128 ENSG00000070985 ENSG00000137841 PMC3887879__F3 Nutrient signaling to mTORC1 ENSG00000168003 ENSG00000130147 ENSG00000198793 ENSG00000167965 ENSG00000103257 ENSG00000115419 ENSG00000175792 PMC3887879__F1 MTOR signaling pathway ENSG00000145979 ENSG00000155792 PMC4555691__F1 Schematic representation of sarcosine pathway ENSG00000179761 PMC8979868__F2 Novel insights on GM1 and Parkinson's disease: A critical review ENSG00000069482 ENSG00000111728 ENSG00000101638 ENSG00000158470 ENSG00000115525 ENSG00000148154 PMC3498346__F1 Impaired Skeletal Muscle Regeneration in the Absence of Fibrosis during Hibernation in 13-Lined Ground Squirrels ENSG00000009709 ENSG00000111046 ENSG00000111049 PMC5701683__F2 Signal transduction in melanoma with regard to the role of the SOX10-MITF pathway ENSG00000092445 ENSG00000157764 ENSG00000261857 ENSG00000198793 PMC4318882__F7 The murine parturition pathway ENSG00000291507 ENSG00000173757 PMC8192743__F12 Mechanistic insights into TNFR1/MADD death domains in Alzheimer’s disease through conformational molecular dynamic analysis ENSG00000102871 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC8038160__F4 Flavonoids modulate growth pathways in cancer ENSG00000205221 ENSG00000138798 ENSG00000198793 ENSG00000284161 ENSG00000155792 ENSG00000167658 ENSG00000146648 PMC8038160__F2 Flavonoids modulate inflammation and immunity pathways in cancer ENSG00000162711 ENSG00000087245 ENSG00000205221 ENSG00000102871 ENSG00000291971 ENSG00000082512 ENSG00000136869 ENSG00000100985 ENSG00000175104 ENSG00000127191 ENSG00000168610 PMC3649201__F1 Current view on the complex interplay of pathogenic factors in cholesterol gallstone formation ENSG00000138075 ENSG00000143921 PMC7838196__F8 PI3K-AKT signaling pathway ENSG00000177455 ENSG00000002330 ENSG00000186716 ENSG00000198793 PMC8468898__F4 Validation and Selection of New Reference Genes for RT-qPCR Analysis in Pediatric Glioma of Different Grades ENSG00000131473 ENSG00000169710 ENSG00000099194 ENSG00000062485 PMC4710243__F1 Beta-Catenin participates in cadherin-mediated cell adhesion and is a transcriptional coactivator in the canonical Wnt signaling pathway ENSG00000134982 PMC4308835__F1 Nuclear factorK B activation pathways ENSG00000104856 ENSG00000170458 ENSG00000136869 PMC3703119__F5 Schematic representation of the pathogenetic mechanism of AD copper phenotype ENSG00000173163 ENSG00000123191 ENSG00000177556 PMC4046186__F1 Intrinsic and extrinsic apoptosis signaling pathways (adapted from ref ENSG00000132906 ENSG00000102871 ENSG00000138794 ENSG00000120868 ENSG00000168040 ENSG00000064012 ENSG00000164305 PMC4947825__F1 Cascades of the coagulation system ENSG00000003436 ENSG00000110799 ENSG00000173599 ENSG00000122194 PMC4947825__F2 Interactions between coagulation and inflammation during IAV infection ENSG00000003436 ENSG00000110799 ENSG00000162692 PMC4965186__F5 a) Systems modeling framework used in this study ENSG00000197713 ENSG00000102539 PMC11032739__F7 Musashi2 affecting radiosensitivity of lung cancer by modulating DNA damage repair ENSG00000188486 ENSG00000175054 PMC7226820__F3 Main signaling pathways involving LSEC during liver regeneration ENSG00000019991 ENSG00000148400 ENSG00000276799 PMC4629055__F2 Divergent macrophage activation pathway ENSG00000102962 ENSG00000108691 ENSG00000275385 ENSG00000102970 PMC9234708__F3 Biomineralization associated alkaline phosphatase as a potential marker of bone metastasis in the patients with invasive breast cancer ENSG00000110203 ENSG00000110244 ENSG00000138792 ENSG00000162551 ENSG00000020633 ENSG00000170262 ENSG00000163295 ENSG00000135324 ENSG00000112293 ENSG00000132170 ENSG00000143512 ENSG00000172901 ENSG00000159216 ENSG00000174059 ENSG00000163286 PMC8038136__F1 CK1A and CK2 regulate many cellular processes that sustain the tumor phenotype ENSG00000128272 ENSG00000134982 ENSG00000105401 ENSG00000198793 ENSG00000168036 ENSG00000198286 PMC3960188__F1 mTOR pathway in colorectal cancer: an update ENSG00000169047 PMC4669955__F2 Emerging Role of ABL Kinases in Solid Tumors ENSG00000038382 ENSG00000168214 ENSG00000291971 ENSG00000198793 ENSG00000163914 ENSG00000143322 ENSG00000173406 ENSG00000121966 PMC3960188__F2 mTOR pathway in colorectal cancer: an update ENSG00000106070 ENSG00000198793 ENSG00000118515 ENSG00000164327 PMC2688755__F2 Network of Conserved Damage Survival Pathways Revealed by a Genomic RNAi Screen ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000144554 ENSG00000132646 ENSG00000149273 ENSG00000139372 ENSG00000177084 ENSG00000139618 PMC3721286__F3 Simplified scheme presenting multiple feedback loops in the EGFR pathway ENSG00000128016 ENSG00000185022 ENSG00000144749 ENSG00000177606 ENSG00000136997 ENSG00000146648 PMC7864484__F2 Nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family apoptosis inhibitory protein (NAIP)-NLR family caspase recruitment domain-containing protein 4 (NLRC4) inflammasome-mediated PANoptosis, inflammatory cell death ENSG00000278718 ENSG00000140968 ENSG00000091106 ENSG00000168404 ENSG00000064012 ENSG00000164305 PMC3730684__F1 The Smad-dependent TGFB signalling pathway upon stimulation with TGFB and BMP ENSG00000170365 ENSG00000090402 ENSG00000205221 PMC9260904__F10 Genome-wide Meta-analysis Reveals New Gene Signatures and Potential Drug Targets of Hypertension ENSG00000148926 ENSG00000221869 ENSG00000146648 PMC7524949__F2 Synthesis, release, and metabolism of intra- and extra-cellular purines ENSG00000196839 ENSG00000291814 PMC2725405__F6 Regulation of IFN response genes by TLR3 signaling ENSG00000164342 PMC3832239__F2 Mitochondrial Retrograde Signaling at the crossroads of tumor bioenergetics, genetics and epigenetics ENSG00000196218 ENSG00000140443 PMC8946699__F1 New Directions and Challenges in Targeted Therapies of Advanced Bladder Cancer: The Role of FGFR Inhibitors ENSG00000198793 PMC4134018__F3 Molecular pathogenesis of the obligate intracellular bacterium Coxiella burnetii ENSG00000140379 ENSG00000171791 PMC4383015__F5 Foxp3-biding genes in ‘pathway in cancer’ ENSG00000134086 ENSG00000128602 PMC7048211__F4 Proposed direct role of HTRA1 in bone formation ENSG00000170365 ENSG00000029559 ENSG00000198793 PMC3919163__F2 LPS receptor signaling pathways ENSG00000183735 ENSG00000172005 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC3271653__F1 Testosterone signaling pathways ENSG00000291971 ENSG00000146648 PMC8538586__F3 Forms and Methods for Interferon’s Encapsulation ENSG00000088888 ENSG00000115415 ENSG00000157601 ENSG00000185745 ENSG00000243646 ENSG00000142166 PMC6174781__F4 Colon Epithelial MicroRNA Network in Fatty Liver ENSG00000087245 ENSG00000149968 ENSG00000066044 ENSG00000115268 ENSG00000157227 ENSG00000067606 ENSG00000115718 PMC10744281__F1 Interconnection of glycolysis with other metabolic pathways ENSG00000065833 ENSG00000122966 ENSG00000138798 ENSG00000198793 ENSG00000113161 ENSG00000114268 ENSG00000169710 ENSG00000146701 ENSG00000159399 PMC10744281__F3 Apoptotic process by glycolysis and lipid metabolism in glioma ENSG00000169710 ENSG00000171791 ENSG00000168040 ENSG00000159399 PMC10744281__F4 Autophagy by glycolysis, lipid metabolism, and glutamine in glioma ENSG00000177169 ENSG00000152348 ENSG00000083290 ENSG00000138798 ENSG00000198793 ENSG00000112561 ENSG00000113161 ENSG00000169710 ENSG00000171791 ENSG00000204673 ENSG00000096717 ENSG00000115419 ENSG00000159399 PMC5549471__F2 HN inhibits OS and ER stress in RPE by direct and indirect mechanisms ENSG00000128272 ENSG00000144895 ENSG00000168610 PMC6290495__F4 Regulatory model for the flow pathway of central carbon metabolism and a proposed scheme for lipid biosynthesis in T ENSG00000198670 ENSG00000105953 ENSG00000100294 ENSG00000062485 PMC5818417__F2 Anti-fibrotic effect of selected polyphenols ENSG00000086991 PMC4691085__F2 Crucial role of miRNAs in coordinating vast prostate cancer (PC) metabolic processes ENSG00000113161 ENSG00000169710 ENSG00000115419 PMC3841791__F9 Predicted upstream regulators inhibited in DA rats but activated in congenics ENSG00000100906 ENSG00000173039 ENSG00000175592 ENSG00000168036 ENSG00000124762 ENSG00000132170 ENSG00000245848 ENSG00000172216 ENSG00000177606 ENSG00000136997 ENSG00000150907 ENSG00000185591 ENSG00000079435 ENSG00000139687 PMC4563160__F8 FASN inhibition blocks metabolic and signal transduction pathways vital to cancer cell growth, proliferation, and survival ENSG00000281324 ENSG00000198793 ENSG00000136997 ENSG00000169710 ENSG00000168036 PMC3789231__F7 Mechanism for epithelial–mesenchymal transition and anoikis resistance in breast cancer triggered by zinc channel ZIP6 and STAT3 (signal transducer and activator of transcription 3) ENSG00000166167 ENSG00000134759 ENSG00000168610 ENSG00000146648 PMC6346071__F1 Cysteine anabolism and catabolism pathways ENSG00000125166 PMC4086482__F1 Phosphoinositide-3-kinase-Akt-mTOR pathway ENSG00000198793 PMC8394255__F2 Insights on the Regeneration Potential of Müller Glia in the Mammalian Retina ENSG00000145321 ENSG00000168036 ENSG00000168610 PMC4134018__F1 Molecular pathogenesis of the obligate intracellular bacterium Coxiella burnetii ENSG00000102189 ENSG00000174903 ENSG00000163914 PMC5635482__F1 DNA interstrand crosslink (ICL) repair: Crosstalk between the Fanconi Anemia (FA) pathway, translesion synthesis (TLS) and homologous recombination (HR) ENSG00000181544 ENSG00000187790 ENSG00000187741 ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000166508 ENSG00000093009 ENSG00000175054 ENSG00000144554 ENSG00000132646 ENSG00000162607 ENSG00000051180 PMC6927724__F8 MicroRNA-23a-3p improves traumatic brain injury through modulating the neurological apoptosis and inflammation response in mice ENSG00000198793 ENSG00000154059 PMC7227813__F2 Anti-lipolysis regulation by insulin on the morphological differences of adipose tissue ENSG00000169047 PMC8022592__F5 Differential regulation of breast cancer cell growth by methyljasmonate (MeJA) or MeJA‐treated leaf disks ENSG00000112576 ENSG00000094804 ENSG00000123374 PMC11079205__F3 GLP-1 effects on bone ENSG00000033327 ENSG00000026103 PMC11079205__F4 Incretin hormones’ effect on bone ENSG00000152266 ENSG00000159224 ENSG00000131096 ENSG00000010310 PMC3704444__F1 Interaction between quality control systems for ER protein folding and RNA biogenesis ENSG00000107371 ENSG00000144895 ENSG00000151461 ENSG00000083520 ENSG00000070366 ENSG00000157106 PMC11012798__F2 C and N metabolisms affected by N sources ENSG00000111816 PMC11079205__F1 Bone remodeling is a dynamic process that is completed with the participation of BMU ENSG00000178860 ENSG00000152266 PMC11079205__F2 The GM and gut hormones on bone metabolism ENSG00000205221 ENSG00000131096 PMC3961644__F8 Proposed model for the negative or positive regulation of chondrocyte maturation or apoptosis by Smpd3/nSMase2, respectively ENSG00000139219 ENSG00000170961 ENSG00000125398 ENSG00000157766 PMC11033413__F2 Progress of medicinal plants and their active metabolites in ischemia-reperfusion injury of stroke: a novel therapeutic strategy based on regulation of crosstalk between mitophagy and ferroptosis ENSG00000186575 ENSG00000167468 ENSG00000197429 ENSG00000113161 ENSG00000135245 ENSG00000115419 PMC12154018__F3 Inhibitors targeting the PI3K/Akt pathway, clinically approved for cancer treatment PMC12154018__F1 PI3K/Akt signaling pathway ENSG00000198793 ENSG00000155792 ENSG00000167965 ENSG00000146648 ENSG00000186654 PMC5924546__F3 Wnt signaling pathway regulates deiodinases ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC1860011__F2 PPARG as a new therapeutic target in inflammatory bowel diseases ENSG00000177606 ENSG00000162692 PMC4184787__F2 Gene Expression during the Generation and Activation of Mouse Neutrophils: Implication of Novel Functional and Regulatory Pathways ENSG00000150782 ENSG00000042832 ENSG00000100979 ENSG00000085871 ENSG00000167780 ENSG00000144959 PMC3409471__F2 Clinical Implications of Cancer Stem Cell Biology in Hepatocellular Carcinoma ENSG00000165556 ENSG00000087095 ENSG00000138795 ENSG00000141448 ENSG00000119888 ENSG00000134982 ENSG00000168036 ENSG00000118777 ENSG00000168610 ENSG00000146648 PMC6949069__F6 The breast cancer pathway ENSG00000157404 ENSG00000139618 PMC8194146__F5 Utilizing the Hippo pathway as a therapeutic target for combating endocrine-resistant breast cancer ENSG00000154342 ENSG00000132471 ENSG00000157933 ENSG00000177971 ENSG00000168036 ENSG00000111186 ENSG00000146648 PMC8194146__F7 Utilizing the Hippo pathway as a therapeutic target for combating endocrine-resistant breast cancer PMC4290680__F1 Structural model of and cell signaling pathways triggered by ManLAM and its biosynthetic precursors LM and PIMs ENSG00000174125 ENSG00000187796 ENSG00000170458 ENSG00000177606 ENSG00000141068 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC4290680__F2 ManLAM and PIM action on phagosome maturation and autophagy ENSG00000177169 ENSG00000111537 ENSG00000198793 ENSG00000119396 PMC7227813__F1 Anti-lipolytic action of insulin ENSG00000149311 PMC8194146__F2 Utilizing the Hippo pathway as a therapeutic target for combating endocrine-resistant breast cancer ENSG00000114978 ENSG00000150457 ENSG00000131023 PMC5710110__F2 Transforming growth factor B (TGFB)-induced Smad signaling pathway ENSG00000136807 ENSG00000135446 ENSG00000132964 ENSG00000283060 ENSG00000125968 PMC5710110__F3 Transforming growth factor B (TGFB)-induced transcriptional program and its alterations in cancer ENSG00000136997 ENSG00000205250 ENSG00000162772 ENSG00000176165 PMC8194146__F3 Utilizing the Hippo pathway as a therapeutic target for combating endocrine-resistant breast cancer ENSG00000150457 ENSG00000131023 PMC8194146__F4 Utilizing the Hippo pathway as a therapeutic target for combating endocrine-resistant breast cancer ENSG00000143320 ENSG00000165244 ENSG00000150457 ENSG00000131023 PMC6395693__F5 Transcription factor regulatory effect network identified using Ingenuity Pathway Analysis (IPA) ENSG00000122367 ENSG00000135547 ENSG00000142798 ENSG00000073614 ENSG00000285109 ENSG00000092054 ENSG00000183072 ENSG00000163565 ENSG00000100345 ENSG00000197616 PMC8393760__F4 Molecular Aspect of Nephrolithiasis Development ENSG00000036473 PMC8393760__F3 Molecular Aspect of Nephrolithiasis Development ENSG00000291814 ENSG00000198931 ENSG00000158125 PMC6834311__F2 The most common signaling pathways influenced by probiotic strains employed in C ENSG00000168036 PMC7763898__F2 MicroRNAs expressed in periodontitis and their target in alveolar bone ENSG00000204103 ENSG00000162599 PMC7219112__F7 Gene-Concept network plot shows the linkages between differentially expressed genes for MAPK pathway-mutated (versus MAPK-WT) HNSCC tumors and GSEA enriched biological concepts ENSG00000110700 ENSG00000291931 ENSG00000265681 ENSG00000241553 ENSG00000121067 ENSG00000180644 ENSG00000108107 ENSG00000078967 ENSG00000064666 ENSG00000063177 ENSG00000183735 ENSG00000105640 ENSG00000114503 ENSG00000144713 ENSG00000166441 ENSG00000159128 ENSG00000170860 ENSG00000164587 ENSG00000137033 ENSG00000162244 ENSG00000142534 ENSG00000108342 ENSG00000198242 ENSG00000109943 ENSG00000205220 ENSG00000010310 ENSG00000188389 ENSG00000130255 ENSG00000113384 ENSG00000101082 ENSG00000197070 ENSG00000172939 ENSG00000107020 ENSG00000013374 ENSG00000026751 ENSG00000172936 ENSG00000146070 ENSG00000163634 ENSG00000115523 ENSG00000204397 ENSG00000114737 ENSG00000163812 ENSG00000274513 ENSG00000168062 ENSG00000166527 ENSG00000166523 ENSG00000130775 ENSG00000197958 ENSG00000177600 ENSG00000168028 ENSG00000143185 ENSG00000115268 ENSG00000172239 ENSG00000164284 ENSG00000169230 ENSG00000129048 ENSG00000114745 ENSG00000141574 ENSG00000124279 ENSG00000288675 ENSG00000169359 ENSG00000284903 ENSG00000171680 ENSG00000174946 ENSG00000110852 ENSG00000182179 ENSG00000135655 ENSG00000173821 ENSG00000116663 ENSG00000197646 ENSG00000254999 ENSG00000136247 ENSG00000178445 ENSG00000173369 ENSG00000205809 ENSG00000163734 ENSG00000164068 ENSG00000186432 ENSG00000132109 ENSG00000125148 ENSG00000077984 ENSG00000167658 ENSG00000177954 ENSG00000185885 ENSG00000278270 ENSG00000154451 ENSG00000135077 ENSG00000164953 ENSG00000126264 ENSG00000012061 ENSG00000163512 ENSG00000164062 ENSG00000197728 ENSG00000138326 ENSG00000188846 ENSG00000143951 ENSG00000163528 ENSG00000121542 ENSG00000089012 ENSG00000239713 ENSG00000058729 ENSG00000291873 ENSG00000173208 ENSG00000172183 ENSG00000145604 ENSG00000142541 ENSG00000111537 ENSG00000175193 ENSG00000174748 ENSG00000164902 ENSG00000167535 ENSG00000146216 ENSG00000145649 ENSG00000090097 ENSG00000105287 ENSG00000127507 PMC3620096__F1 Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles ENSG00000118508 ENSG00000123892 ENSG00000107165 PMC3127250__F1 Autophagy and the integrated stress response ENSG00000177169 ENSG00000152348 ENSG00000110497 ENSG00000198382 ENSG00000083290 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000062716 PMC5557591__F5 Effect of masticatory stimulation on the quantity and quality of saliva and the salivary metabolomic profile ENSG00000081181 ENSG00000036473 ENSG00000146701 ENSG00000102977 PMC6052717__F2 Signalling pathways involved in ccRCC ENSG00000128602 ENSG00000168610 PMC4324684__F9 Proposed pathway of cytosolic jadomycin-induced ROS and their metabolism within MCF7 breast cancer cells ENSG00000105227 PMC3670238__F1 Spectrum of STAT functions in mammary gland development ENSG00000120833 ENSG00000105397 ENSG00000170458 ENSG00000033800 ENSG00000124107 ENSG00000107485 ENSG00000131724 ENSG00000128342 ENSG00000115461 ENSG00000113494 PMC7918168__F6 Action mechanism by gallic acid and rutin on mitochondrial functions in C2C12 myotubes ENSG00000090432 ENSG00000117118 ENSG00000116688 ENSG00000119013 ENSG00000171109 ENSG00000057663 ENSG00000106459 ENSG00000214253 PMC6140703__F8 A schematic model of GC development ENSG00000002330 ENSG00000166851 PMC7461761__F1 Evolutionary Origins of Programmed Cell Death Signaling ENSG00000278718 ENSG00000179041 ENSG00000102871 ENSG00000120868 ENSG00000168040 ENSG00000168404 ENSG00000064012 ENSG00000285379 PMC5591063__F4 Changes in Adipose Tissue During Weight Gain ENSG00000108691 PMC6187096__F2 Ginsenoside Rh2 epigenetically affects genes in the cell-mediated immune response pathway ENSG00000145362 ENSG00000146376 ENSG00000147437 ENSG00000230989 ENSG00000137757 ENSG00000149091 ENSG00000152689 ENSG00000175029 ENSG00000110693 ENSG00000291983 ENSG00000171777 ENSG00000073614 ENSG00000167964 ENSG00000110218 ENSG00000123636 ENSG00000127838 ENSG00000255501 PMC6517553__F3 General principle of the HSV-TK suicide gene system ENSG00000149311 ENSG00000168040 ENSG00000026103 PMC7060917__F4 Molecular docking and network connections of active compounds from the classical herbal formula Ding Chuan Tang ENSG00000134982 ENSG00000197971 ENSG00000186716 PMC7060917__F5 Molecular docking and network connections of active compounds from the classical herbal formula Ding Chuan Tang ENSG00000128052 ENSG00000146648 ENSG00000113448 ENSG00000132170 PMC5512555__F3 Notch signaling in the mammalian ovary ENSG00000152661 ENSG00000285109 ENSG00000146857 ENSG00000188372 ENSG00000184916 ENSG00000168610 ENSG00000203857 ENSG00000106003 ENSG00000187513 ENSG00000186766 ENSG00000164404 ENSG00000130385 ENSG00000128917 ENSG00000106410 ENSG00000183733 PMC3823599__F7 MiR-103 Controls Milk Fat Accumulation in Goat (Capra hircus) Mammary Gland during Lactation ENSG00000151726 ENSG00000135218 ENSG00000161533 ENSG00000169710 ENSG00000285482 ENSG00000160179 ENSG00000099194 PMC7221190__F2 Complement-driven accelerated renal senescence after IRI-AKI leading to CKD progression ENSG00000164151 ENSG00000162337 ENSG00000163235 ENSG00000157193 ENSG00000168036 ENSG00000062485 PMC8847224__F2 Dissecting the Crosstalk Between Nrf2 and NFKB Response Pathways in Drug-Induced Toxicity ENSG00000104856 ENSG00000173039 ENSG00000111321 PMC12079202__F6 Overall network diagram of “drug-target-disease-pathway” ENSG00000104368 PMC10607277__F9 Compound–disease–therapeutic targets-core pathways network; red triangles represent diseases, blue triangles represent compounds, purple ovals represent pathways, and green ovals represent targets ENSG00000162889 ENSG00000149968 ENSG00000135446 ENSG00000150907 ENSG00000125538 ENSG00000166501 ENSG00000196591 ENSG00000173039 ENSG00000123374 ENSG00000171791 PMC11022503__F8 Proposed mechanism of erroneous differentiation of TSPCs under high glucose ENSG00000189403 ENSG00000260428 ENSG00000108821 ENSG00000000005 PMC6612049__F1 Mechanisms of ionizing radiation sensitizing and resistant effects in various subtypes of breast cancer and irradiation-induced apoptosis ENSG00000012048 ENSG00000148346 ENSG00000109332 ENSG00000198793 ENSG00000168036 ENSG00000051180 ENSG00000171791 ENSG00000146648 PMC4136419__F1 Targeting the B cell receptor signaling pathway in B lymphoid malignancies ENSG00000177455 ENSG00000136997 ENSG00000197943 ENSG00000010671 ENSG00000198286 PMC4136419__F2 Targeting the B cell receptor signaling pathway in B lymphoid malignancies ENSG00000095585 ENSG00000166349 ENSG00000136997 ENSG00000112182 ENSG00000118971 ENSG00000104432 ENSG00000175097 ENSG00000010671 PMC9221006__F3 Histone Demethylase JMJD2D: A Novel Player in Colorectal and Hepatocellular Cancers ENSG00000087245 ENSG00000111537 ENSG00000125398 ENSG00000198793 ENSG00000168036 ENSG00000185591 ENSG00000100985 ENSG00000125347 ENSG00000168610 PMC4698274__F1 Innate Immunity against Leishmania Infections ENSG00000162711 ENSG00000150782 ENSG00000239732 ENSG00000125538 ENSG00000172936 ENSG00000164342 PMC10377042__F2 Potential Influence of Uremic Toxins on the Homeostasis of Bones and Muscles in Chronic Kidney Disease ENSG00000152266 ENSG00000106546 PMC9312989__F6 Target-Based Small Molecule Drug Discovery for Colorectal Cancer: A Review of Molecular Pathways and In Silico Studies ENSG00000157764 ENSG00000198793 ENSG00000143622 ENSG00000047936 ENSG00000169032 ENSG00000121879 ENSG00000146648 ENSG00000196712 PMC4536957__F2 Schema showing the multiple functions of FOXD1 lineage myofibroblasts in interstitial kidney disease ENSG00000137673 ENSG00000157227 ENSG00000164690 ENSG00000078098 ENSG00000087116 ENSG00000151388 PMC7796309__F1 Mitochondria-associated membranes (MAMs): a potential therapeutic target for treating Alzheimer’s disease ENSG00000113600 PMC7661798__F4 Cellular response to growth factor (GF) via its receptor ENSG00000198793 ENSG00000121879 PMC6111708__F2 Hippo-YAP signaling and the pathogenesis of gastric cancer ENSG00000124092 ENSG00000229859 ENSG00000108242 ENSG00000186009 ENSG00000113805 ENSG00000228278 ENSG00000229314 ENSG00000196344 ENSG00000183607 ENSG00000186340 ENSG00000108821 ENSG00000196620 ENSG00000078098 ENSG00000154096 ENSG00000164694 ENSG00000147606 ENSG00000160182 ENSG00000160181 ENSG00000106483 ENSG00000169605 ENSG00000157005 ENSG00000164120 ENSG00000151388 ENSG00000117122 ENSG00000134827 ENSG00000113296 ENSG00000198074 ENSG00000137573 ENSG00000256713 ENSG00000169435 PMC9312989__F3 Target-Based Small Molecule Drug Discovery for Colorectal Cancer: A Review of Molecular Pathways and In Silico Studies ENSG00000156076 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000292149 ENSG00000168036 ENSG00000106483 ENSG00000104332 ENSG00000106829 ENSG00000065717 ENSG00000184675 ENSG00000120057 ENSG00000155011 ENSG00000136997 ENSG00000050165 ENSG00000104371 ENSG00000108375 PMC3307371__F8 Exercise can increase small heat shock proteins (sHSP) and pre- and post-synaptic proteins in the hippocampus ENSG00000284774 ENSG00000105723 PMC4667791__F5 MAPK pathway has been invoked in phospholipase A2 activity that could release arachidonic acid, perhaps in concert with VEGF, and thereby amplify 20-HETE formation () ENSG00000186115 ENSG00000187048 ENSG00000186160 ENSG00000186377 PMC8626287__F2 Implication of the circadian clock in the regulation of neural signaling and behavior ENSG00000198793 ENSG00000132326 PMC8204249__F5 Inflammatory Pathophysiology as a Contributor to Myeloproliferative Neoplasms ENSG00000178860 ENSG00000125538 ENSG00000277943 PMC11987923__F3 Tumor immune microenvironment in cholangiocarcinoma ENSG00000066468 ENSG00000134982 PMC8204249__F3 Inflammatory Pathophysiology as a Contributor to Myeloproliferative Neoplasms ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000064012 ENSG00000285379 PMC8204249__F4 Inflammatory Pathophysiology as a Contributor to Myeloproliferative Neoplasms ENSG00000122025 ENSG00000143546 ENSG00000117400 ENSG00000173039 ENSG00000172936 ENSG00000105810 ENSG00000184216 PMC10218668__F1 Therapeutic peptides for lung diseases ENSG00000162711 ENSG00000105550 ENSG00000146469 ENSG00000173786 PMC3381956__F1 Signaling pathways and their targeted therapies in NSCLC ENSG00000019991 ENSG00000157404 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000168040 ENSG00000146648 PMC4598753__F1 Nuclear receptors can alter NFKB signaling and activity ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC3495118__F1 Transcriptional regulation of the cytoprotective phase 2 genes under control of the transcriptional factor nuclear factor-E2 p45-related factor 2 (Nrf2) ENSG00000062485 ENSG00000079999 PMC7750564__F1 NFKB signaling pathway is involved in the transcription of HIV which can be exploited for HIV cure studies ENSG00000023445 ENSG00000104856 ENSG00000110330 ENSG00000131323 ENSG00000127191 PMC7072180__F4 FUT8 overexpression promotes DNA replication ENSG00000132646 ENSG00000172005 ENSG00000123374 PMC6068284__F3 Fumarase functions in the human and yeast DNA damage response (DDR) to double-strand breaks (DSBs) PMC7281640__F2 Clinicopathological and prognostic significance and molecular mechanisms governing uveal melanoma ENSG00000163930 ENSG00000115524 ENSG00000173674 ENSG00000088256 PMC9144890__F5 CD44 Mediates Oral Squamous Cell Carcinoma-Promoting Activity of MRE11 via AKT Signaling ENSG00000026508 ENSG00000198125 PMC1839891__F10 In this model, the tumor growth process is replaced with the cell cycle model from figure 7 ENSG00000134982 ENSG00000128602 PMC9832433__F4 Neutrophil, neutrophil extracellular traps and endothelial cell dysfunction in sepsis ENSG00000134982 ENSG00000173599 ENSG00000136869 ENSG00000005381 PMC6180192__F1 Nuclear factor erythroid 2-related factor 2 (NRF2) activation ENSG00000100387 ENSG00000113558 ENSG00000062485 ENSG00000079999 PMC9832433__F2 Neutrophil, neutrophil extracellular traps and endothelial cell dysfunction in sepsis ENSG00000180210 ENSG00000150907 ENSG00000136869 ENSG00000162692 ENSG00000005381 PMC9709224__F7 Oleic acid-induced steatosis model establishment in LMH cells and its effect on lipid metabolism ENSG00000042832 ENSG00000138823 ENSG00000169710 PMC6094051__F6 Models for Golgi fragmentation induced by truncated APC ENSG00000134982 ENSG00000163914 ENSG00000115266 PMC8564353__F1 Exosome CTLA-4 Regulates PTEN/CD44 Signal Pathway in Spleen Deficiency Internal Environment to Promote Invasion and Metastasis of Hepatocellular Carcinoma ENSG00000026508 PMC8204249__F1 Inflammatory Pathophysiology as a Contributor to Myeloproliferative Neoplasms ENSG00000110395 ENSG00000117400 ENSG00000168610 PMC4983011__F1 Processes involved in particle-induced pro-IL-1B expression ENSG00000137033 ENSG00000189403 PMC5830721__F5 HIF-1 signalling pathway is enriched in proteins containing labile disulfide bonds ENSG00000134086 ENSG00000138030 ENSG00000198793 ENSG00000072274 ENSG00000136869 ENSG00000111816 ENSG00000168610 PMC7859462__F4 Impact of 3′UTR APA on its target mRNA and protein PMC8860994__F8 Network Pharmacology and Experimental Verification to Explore the Potential Mechanism of Yin-Huo-Tang for Lung Adenocarcinoma Recurrence ENSG00000033327 ENSG00000102871 ENSG00000010810 ENSG00000163914 ENSG00000127191 ENSG00000102172 PMC7355051__F3 Targeting mitochondria using endogenous cardioprotective strategies ENSG00000116688 ENSG00000145321 ENSG00000168610 PMC7490471__F1 ZEB1-Mediated Transcriptional Upregulation of circWWC3 Promotes Breast Cancer Progression through Activating Ras Signaling Pathway ENSG00000047644 ENSG00000138798 ENSG00000146648 PMC5173116__F7 Reverse-mode NCX1 activity inhibitor KB-R7943 promotes prostate cancer cell death by activating the JNK pathway and blocking autophagic flux ENSG00000099330 ENSG00000198793 ENSG00000173599 PMC5007556__F1 SPATA2 – Keeping the TNF signal short and sweet ENSG00000104856 ENSG00000064042 ENSG00000153820 ENSG00000137275 ENSG00000102871 ENSG00000138594 ENSG00000108443 ENSG00000127191 ENSG00000168610 ENSG00000183735 ENSG00000117020 ENSG00000060339 ENSG00000083799 ENSG00000168404 PMC5899030__F3 multiple neuropeptides and receptors regulate the activity of neurons in feeding circuits ENSG00000123901 ENSG00000173599 ENSG00000115138 ENSG00000166603 ENSG00000174946 PMC5770878__F6 The hypothesized protective effect of CR on retinal degeneration by ONVT: the pivotal role of elevated endogenous 3HB via ketolysis ENSG00000181019 ENSG00000075239 ENSG00000275544 ENSG00000062485 PMC534909__F2 Fas receptor pathway of apoptosis ENSG00000168040 ENSG00000084774 ENSG00000026103 PMC9484011__F2 Biosynthetic pathway leading to H2S production from L- and D-cysteine PMC534909__F3 Cell survival signaling pathways ENSG00000002330 ENSG00000026103 PMC3903252__F7 Schematic illustration of the TGFB/ENaC pathway in a generalized alveolar epithelial cell monolayer, described in this study ENSG00000173599 ENSG00000086991 ENSG00000143398 PMC7069061__F6 Pathway of multiregulatory effects in Chinese medicine ENSG00000169248 ENSG00000291971 ENSG00000163739 ENSG00000138798 ENSG00000198793 ENSG00000164399 ENSG00000168036 ENSG00000171791 ENSG00000112715 ENSG00000164305 ENSG00000169245 ENSG00000111537 ENSG00000108557 ENSG00000149968 ENSG00000102245 ENSG00000113520 ENSG00000104432 ENSG00000113525 ENSG00000146648 PMC10310766__F2 Canonical pathway of p53 that regulates ferroptosis ENSG00000130876 ENSG00000135423 ENSG00000161905 ENSG00000151012 ENSG00000155287 ENSG00000197635 ENSG00000066044 ENSG00000167468 ENSG00000161513 PMC10310766__F3 Noncanonical pathway of p53 that regulates ferroptosis ENSG00000108839 ENSG00000151012 PMC2674747__F1 Illustration of differences in the expression of genes for early steps of sphingolipid metabolism using a KEGG-based microarray analysis tool (GenMapp v2.1) that has been modified to display this pathway more completely (www.sphingomap.org) ENSG00000139624 ENSG00000100422 ENSG00000063176 ENSG00000223802 ENSG00000154227 ENSG00000188611 ENSG00000143418 ENSG00000163082 PMC9307469__F1 Can iron, zinc, copper and selenium status be a prognostic determinant in COVID-19 patients? ENSG00000140564 ENSG00000130234 ENSG00000184012 ENSG00000049768 ENSG00000276561 ENSG00000142166 PMC6935429__F3 Different DNA repair mechanisms ENSG00000132646 ENSG00000070950 PMC5507876__F8 The diagram of rGal3C regulating NDRG1 through integrin/FAK/SRC pathway ENSG00000291971 PMC3592845__F7 Gli1 Deletion Prevents Helicobacter-Induced Gastric Metaplasia and Expansion of Myeloid Cell Subsets ENSG00000125538 ENSG00000164690 PMC6493027__F2 Ingenuity Pathway Analysis (IPA) of ASS234 treatment ENSG00000087095 ENSG00000127445 ENSG00000156076 ENSG00000137673 ENSG00000134982 ENSG00000163914 ENSG00000026508 ENSG00000168036 ENSG00000104332 ENSG00000196628 PMC5874277__F3 Phospholipase D1 and neurogenesis of neural stem cells ENSG00000070831 ENSG00000173599 ENSG00000121905 ENSG00000168610 PMC9253713__AF1 SUFU suppresses ferroptosis sensitivity in breast cancer cells via Hippo/YAP pathway ENSG00000186575 ENSG00000131023 PMC6738809__F6 Mechanisms involved in vitamin D-mediated immunomodulation of neutrophils ENSG00000111012 ENSG00000172005 ENSG00000172936 ENSG00000175104 PMC8842010__F4 Identifying individualized risk subpathways reveals pan-cancer molecular classification based on multi-omics data ENSG00000002330 ENSG00000070831 ENSG00000134215 ENSG00000115904 ENSG00000164399 ENSG00000105647 ENSG00000169032 ENSG00000100485 ENSG00000121879 ENSG00000141968 ENSG00000156299 ENSG00000169750 ENSG00000149269 ENSG00000160293 ENSG00000077782 ENSG00000292332 ENSG00000104365 ENSG00000188386 ENSG00000100906 ENSG00000109320 ENSG00000027644 ENSG00000173039 ENSG00000065559 ENSG00000165059 ENSG00000213341 ENSG00000120910 ENSG00000221823 ENSG00000066468 ENSG00000017797 ENSG00000117020 ENSG00000160867 ENSG00000177606 ENSG00000006451 ENSG00000144118 ENSG00000134853 ENSG00000146648 PMC3855094__F13 Systematically Studying Kinase Inhibitor Induced Signaling Network Signatures by Integrating Both Therapeutic and Side Effects ENSG00000019991 ENSG00000163235 ENSG00000169047 PMC9301819__F5 Atopic dermatitis and Psoriasis vulgaris -specific DEGs segregate discretely based on unbiased pathway and network analysis ENSG00000265681 ENSG00000187608 ENSG00000162630 ENSG00000128656 ENSG00000163599 ENSG00000198743 ENSG00000203780 ENSG00000054654 ENSG00000122417 ENSG00000170500 ENSG00000120885 ENSG00000115970 ENSG00000135678 ENSG00000273562 ENSG00000146278 ENSG00000089692 ENSG00000111796 ENSG00000168214 ENSG00000172216 ENSG00000122691 ENSG00000183943 ENSG00000196914 ENSG00000056736 ENSG00000159335 ENSG00000213145 ENSG00000275031 ENSG00000023445 ENSG00000130340 ENSG00000107742 ENSG00000221869 ENSG00000185885 ENSG00000154451 ENSG00000292348 ENSG00000101082 ENSG00000087253 ENSG00000008516 ENSG00000118503 ENSG00000185201 ENSG00000164466 ENSG00000107485 ENSG00000115523 ENSG00000128016 ENSG00000123416 ENSG00000163629 ENSG00000181104 ENSG00000197728 ENSG00000115904 ENSG00000175352 ENSG00000103811 ENSG00000147408 ENSG00000150991 ENSG00000071073 ENSG00000104447 ENSG00000125534 ENSG00000112486 ENSG00000182463 ENSG00000175155 ENSG00000143013 ENSG00000124766 ENSG00000107863 ENSG00000291420 ENSG00000135916 ENSG00000112116 ENSG00000241343 ENSG00000010810 ENSG00000147324 ENSG00000177606 ENSG00000102007 ENSG00000167996 ENSG00000110852 ENSG00000152518 ENSG00000139112 PMC2864813__F4A Substance P in Polymicrobial Sepsis: Molecular Fingerprint of Lung Injury in Preprotachykinin-A−/− Mice ENSG00000134339 ENSG00000148346 ENSG00000143546 ENSG00000163220 ENSG00000125538 ENSG00000181374 ENSG00000100985 ENSG00000136689 ENSG00000171051 ENSG00000179295 PMC8842010__F6 Identifying individualized risk subpathways reveals pan-cancer molecular classification based on multi-omics data ENSG00000087095 ENSG00000005339 ENSG00000157764 ENSG00000134982 ENSG00000140575 ENSG00000130522 ENSG00000173083 ENSG00000168036 ENSG00000276876 ENSG00000100592 ENSG00000111837 ENSG00000136997 ENSG00000253729 PMC7156871__F3 MicroRNA (miR)‐302/367 family participates in networks that regulate cancer hallmarks ENSG00000147649 ENSG00000150457 ENSG00000231179 ENSG00000118971 ENSG00000043093 ENSG00000121966 ENSG00000115884 ENSG00000112242 ENSG00000112210 ENSG00000198838 ENSG00000204520 ENSG00000146648 ENSG00000140443 PMC4139671__F5 Wnt/Beta-catenin signaling pathway ENSG00000138795 ENSG00000134982 ENSG00000168036 PMC3283604__F6 TSC1/2 Signaling Complex Is Essential for Peripheral Naïve CD8+ T Cell Survival and Homeostasis in Mice ENSG00000198793 ENSG00000168685 PMC8157020__F1 Novel Target Opportunities in Non-Metastatic Castrate Resistant Prostate Cancer ENSG00000198793 PMC5905598__F4 Genes of complexes coding for the mitochondrial oxidative phosphorylation and tricarboxylic acid cycle (TCA) ENSG00000132423 ENSG00000139180 ENSG00000136521 ENSG00000184983 ENSG00000166278 ENSG00000112992 ENSG00000146701 ENSG00000082212 ENSG00000113845 ENSG00000166136 ENSG00000062485 PMC8157020__F2 Novel Target Opportunities in Non-Metastatic Castrate Resistant Prostate Cancer ENSG00000010810 ENSG00000168610 PMC4732299__F5 Alterations in the levels of metabolites and mRNA transcripts that are crucial to energy metabolism in NAF-1(−) MCF-7 cells ENSG00000131473 ENSG00000151376 ENSG00000159224 ENSG00000065833 ENSG00000100412 ENSG00000095321 ENSG00000169710 ENSG00000099194 ENSG00000076555 ENSG00000146701 ENSG00000145414 ENSG00000198721 PMC10572209__F7 Molecular pathways in Hep3B cell line ENSG00000002330 ENSG00000135446 ENSG00000198517 PMC11397714__F3 IFN signaling activates the JAK-STAT pathway, leading to the transcription of genes involved in the immune response (Created with https://www ENSG00000159128 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000185436 ENSG00000169047 ENSG00000027697 ENSG00000147896 ENSG00000142166 PMC6027339__F2 Chronic active BCR signaling in lymphoid malignancies ENSG00000177455 ENSG00000095585 ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000197943 ENSG00000010671 PMC4819199__F7 Intestinal Insulin Signaling Encodes Two Different Molecular Mechanisms for the Shortened Longevity Induced by Graphene Oxide in Caenorhabditis elegans PMC4693877__F2 Bacterial components that affect innate and adaptive immunity in the intestine ENSG00000106546 PMC11848412__F5 A, Schematic illustration of how calcium dysregulation in the aging association cortex leads to activation of calpain‐2 and an exacerbation in sporadic AD pathology ENSG00000106683 ENSG00000142192 ENSG00000067900 ENSG00000198626 PMC11397714__F1 Canonical TNFA signaling pathway activates NFKB through TNF receptor binding, involving TRADD, RIP-1, and the IKK complex, leading to the transcription of various genes that are involved in the immune response (Created with https://www ENSG00000173039 ENSG00000157625 PMC6417013__F1 Main aspects of folate receptor signaling and C1 metabolism discussed during the meeting ENSG00000284320 ENSG00000065911 ENSG00000168610 PMC11397714__F2 IL-1B signaling pathway activates NFKB and MAPKs through the IL-1 receptor, leading to the transcription of genes involved in inflammation and immune responses (Created with https://www ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC9017388__F6 SLC38A10 Regulate Glutamate Homeostasis and Modulate the AKT/TSC2/mTOR Pathway in Mouse Primary Cortex Cells ENSG00000140992 ENSG00000002330 ENSG00000198793 ENSG00000204673 ENSG00000108443 ENSG00000132356 ENSG00000111725 ENSG00000187840 PMC8476782__F2 Cellular Prion Protein in Cancer Biology: A Potential Therapeutic Target ENSG00000182568 ENSG00000148400 ENSG00000010810 ENSG00000185591 PMC2596750__F8 TNFR1 and LTBR ligation-induced signaling in vascular EC ENSG00000107562 ENSG00000081041 ENSG00000111321 PMC7225294__F11 Proposed model of action and mechanism by which CVB3 infection causes cardiomyocyte death ENSG00000171855 ENSG00000134755 ENSG00000088888 ENSG00000187608 ENSG00000168036 ENSG00000046604 PMC10873402__F5 JAK-STAT signaling pathway ENSG00000134460 ENSG00000213928 ENSG00000090534 ENSG00000185436 ENSG00000187266 ENSG00000100485 ENSG00000100385 ENSG00000172458 ENSG00000142677 ENSG00000123496 ENSG00000184995 ENSG00000117400 ENSG00000228083 ENSG00000164400 ENSG00000186803 ENSG00000147885 ENSG00000292332 ENSG00000120242 ENSG00000162892 ENSG00000214042 ENSG00000159128 ENSG00000112964 ENSG00000119535 ENSG00000147168 ENSG00000137070 ENSG00000108342 ENSG00000027697 ENSG00000145777 ENSG00000292363 ENSG00000138378 ENSG00000105397 ENSG00000115145 ENSG00000113494 ENSG00000016402 ENSG00000168685 ENSG00000110944 ENSG00000171855 ENSG00000188379 ENSG00000198793 ENSG00000115904 ENSG00000164399 ENSG00000103522 ENSG00000105647 ENSG00000168811 ENSG00000121879 ENSG00000174564 ENSG00000164485 ENSG00000291875 ENSG00000142166 ENSG00000137080 ENSG00000179295 ENSG00000150281 ENSG00000145623 ENSG00000177047 ENSG00000122756 ENSG00000292373 ENSG00000113520 ENSG00000147896 ENSG00000131724 ENSG00000288185 ENSG00000292357 ENSG00000128342 ENSG00000113525 ENSG00000104432 ENSG00000236637 ENSG00000099985 ENSG00000242689 ENSG00000110324 ENSG00000105639 ENSG00000234829 ENSG00000168610 ENSG00000162594 ENSG00000096996 ENSG00000117020 ENSG00000111537 ENSG00000145839 ENSG00000115415 ENSG00000173757 ENSG00000164136 ENSG00000291876 ENSG00000243646 ENSG00000113302 ENSG00000171608 PMC10873402__F4 Enrichment analysis for leading target genes ENSG00000178860 ENSG00000243130 PMC8846289__F1 Immune Reconstitution Following Autologous Hematopoietic Stem Cell Transplantation for Multiple Sclerosis: A Review on Behalf of the EBMT Autoimmune Diseases Working Party ENSG00000111537 ENSG00000204520 PMC4135580__F7 Working model for the PEX5L-PEX7-mediated import pathway ENSG00000124587 ENSG00000288217 ENSG00000121680 PMC2737901__F1 Putative biosynthetic pathway of PUFAs in Mortierella alpina 1S-4 ENSG00000100473 PMC5391973__F4 The immune response by Fonsecaea pedrosoi morphotypes in the course of experimental chromoblastomycosis and their role on inflammatory response chronicity ENSG00000170458 ENSG00000125538 ENSG00000177606 ENSG00000080823 ENSG00000172936 ENSG00000150455 ENSG00000276561 PMC8065571__F1 Schematics of the eicosanoids synthesis pathway for the production of prostanoids (Prostaglandins—PGs, Prostacyclin and Thromboxanes—TXs), Leukotrienes (LTs) and resolving mediators including D- and E-series resolvins (Rvs), protectins and maresins ENSG00000226275 PMC4837237__F7 A simplified overview of the ectodysplasin/EDA‐receptor/nuclear factor kappa B (EDA/EDAR/NF‐KB) pathway ENSG00000186197 ENSG00000135960 PMC3051261__F11 Schematic Models of Tap46/Tap42/A4 Functions in TOR Signaling Pathways in Eukaryotes.(A) TOR signaling in yeast ENSG00000198793 PMC8706757__F2 Necroptosis in disease and treatment ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000166278 ENSG00000127191 ENSG00000082512 ENSG00000157625 ENSG00000136869 ENSG00000083799 ENSG00000168404 ENSG00000285379 ENSG00000026103 ENSG00000164342 PMC1964512__F3 Type I IFN innate immune response to adenovirus-mediated IFNG gene transfer contributes to the regression of cutaneous lymphomas ENSG00000120833 ENSG00000102962 ENSG00000089127 ENSG00000105516 ENSG00000163568 ENSG00000196954 ENSG00000168961 ENSG00000102678 ENSG00000148935 ENSG00000276561 ENSG00000069667 ENSG00000135899 ENSG00000169245 ENSG00000067066 ENSG00000108691 ENSG00000134321 ENSG00000188313 ENSG00000115415 ENSG00000138755 ENSG00000123609 ENSG00000163394 ENSG00000115009 ENSG00000143184 PMC8372151__F3 Fibroblast Growth Factor 23 and Left Ventricular Hypertrophy in Chronic Kidney Disease—A Pediatric Perspective ENSG00000118972 ENSG00000152266 ENSG00000160867 PMC9569955__F7 Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation ENSG00000095585 ENSG00000183735 ENSG00000104814 ENSG00000088888 ENSG00000186716 ENSG00000184182 ENSG00000131323 ENSG00000162692 ENSG00000175104 ENSG00000121060 PMC6027339__F1 Oncogenic MyD88 mutations activate the canonical NFKB pathway ENSG00000175104 ENSG00000184216 PMC7765482__F8 Canonical pathways identified from protein co-expression network ENSG00000023445 ENSG00000140992 ENSG00000105329 ENSG00000291971 ENSG00000036672 ENSG00000170558 ENSG00000027697 ENSG00000065559 ENSG00000292363 ENSG00000171791 ENSG00000142166 ENSG00000135077 ENSG00000100290 ENSG00000120742 ENSG00000166501 PMC3612391__F2 Role and mechanism-of-action of Sema3E and Plexin-D1 in vascular and neural development ENSG00000170381 PMC5747488__F13 Parapoxviral virion protein targets the retinoblastoma protein to inhibit NFKB signaling ENSG00000102871 ENSG00000157625 ENSG00000127191 PMC3731808__F6 Comparison of gene expression changes in human bladder cancer and our mouse model based on KEGG pathway analysis ENSG00000149968 ENSG00000124882 ENSG00000135446 ENSG00000138798 ENSG00000136997 ENSG00000112715 ENSG00000139687 ENSG00000124762 ENSG00000137801 PMC5790345__F5 PD173074 inhibits the signal pathway downstream of FGFR1 in ESCC ENSG00000115415 ENSG00000198793 ENSG00000077782 PMC4752998__F1 Epithelial/mesenchymal status of MCs is due to the balance of signals delivered by multiple receptors ENSG00000019991 ENSG00000170365 ENSG00000125538 ENSG00000163914 ENSG00000168610 PMC3429478__F1 Development of Quinoxaline 1, 4-Dioxides Resistance in Escherichia coli and Molecular Change under Resistance Selection ENSG00000182511 ENSG00000042832 PMC5611863__F1 Landscape of new drugs in lymphoma ENSG00000105369 ENSG00000007312 ENSG00000102010 ENSG00000105639 ENSG00000010671 ENSG00000177455 ENSG00000095585 ENSG00000100290 ENSG00000186716 ENSG00000177606 ENSG00000074966 ENSG00000113263 ENSG00000146648 ENSG00000135605 ENSG00000178568 ENSG00000198286 PMC4185881__F1 Formal Modelling of Toll like Receptor 4 and JAK/STAT Signalling Pathways: Insight into the Roles of SOCS-1, InterferonB and Proinflammatory Cytokines in Sepsis ENSG00000183735 ENSG00000170458 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC8997162__F1 Molecularly Targeted Therapy towards Genetic Alterations in Advanced Bladder Cancer ENSG00000066468 ENSG00000065361 ENSG00000160867 ENSG00000077782 ENSG00000146648 PMC8976706__F4 Decellularized extracellular matrix mediates tissue construction and regeneration ENSG00000150457 ENSG00000131023 PMC4410875__F3A Differential microRNA expression tracks neoplastic progression in inflammatory bowel disease-associated colorectal cancer ENSG00000168036 PMC3633815__F1 MTOR signaling pathway ENSG00000177169 ENSG00000163914 ENSG00000118515 PMC2674738__F1 Circulating blood monocytes adhere to activated endothelium at sites of disease or injury ENSG00000173599 ENSG00000198670 ENSG00000121807 PMC6373401__F1 Neuroprotective mechanisms of antidiabetic drugs in the context of Parkinson’s disease dementia ENSG00000198793 ENSG00000119912 ENSG00000115594 PMC8812204__F2 Dual roles of autophagy and the GPCRs-mediating autophagy signaling pathway after cerebral ischemic stroke ENSG00000177169 ENSG00000188554 ENSG00000126775 ENSG00000198793 ENSG00000005893 ENSG00000284099 ENSG00000112561 ENSG00000181467 ENSG00000145782 ENSG00000057663 PMC8812204__F1 Dual roles of autophagy and the GPCRs-mediating autophagy signaling pathway after cerebral ischemic stroke ENSG00000177169 ENSG00000123395 ENSG00000126775 PMC7330432__F1 MicroRNA-4500 Inhibits Migration, Invasion, and Angiogenesis of Breast Cancer Cells via RRM2-Dependent MAPK Signaling Pathway ENSG00000132646 ENSG00000171848 PMC11547832__F8 DOE is involved in the Akt signaling pathway to regulate protein synthesis and lipogenesis ENSG00000125414 ENSG00000169047 PMC8432143__F2 Moving towards clinical trials for mitochondrial diseases ENSG00000143799 PMC7012475__F1 Monocytes in sickle cell disease ENSG00000261857 ENSG00000136869 ENSG00000162692 PMC6486704__F2 Chemoautotroph Ca ENSG00000124479 PMC5615340__F5 Crosslinks between integrin and wnt signalling ENSG00000168036 PMC2909359__F8 Interplay between Foxd3 and Mitf regulates cell fate plasticity in the zebrafish neural crest ENSG00000182578 ENSG00000187140 ENSG00000080166 ENSG00000113263 PMC8889909__F2 Physiological and Pathophysiological Roles of Metabolic Pathways for NET Formation and Other Neutrophil Functions ENSG00000197713 PMC9478117__F8 MiR-33a-5p/CROT axis mediates ovarian cancer cell behaviors and chemoresistance via the regulation of the TGFB signal pathway ENSG00000005469 PMC8445727__F8 Active Ingredients and Potential Mechanisms of the Gan Jiang-Huang Qin-Huang Lian-Ren Shen Decoction against Ulcerative Colitis: A Network Pharmacology and Molecular Docking-Based Study ENSG00000167601 ENSG00000019991 ENSG00000002330 ENSG00000138798 PMC10610499__F5 Interplay between EVs and the TLR4 signaling pathway in the context of HCC ENSG00000197747 ENSG00000189403 ENSG00000136869 ENSG00000146648 PMC11990295__F5 Anthocyanin in modulating PI3K/Akt/FOXO pathway in obesity ENSG00000150907 PMC10610499__F3 Liver manages a complex antigenic load from the blood, relying on immune tolerance mechanisms and mainly LPS tolerance ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC4515857__F3 PTEN localization and interactions with representative partners ENSG00000145241 ENSG00000134982 PMC10610499__F2 TLR4 downstream signaling pathways ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 PMC5446300__F4 T-Lymphocyte Homing: An Underappreciated yet Critical Hurdle for Successful Cancer Immunotherapy ENSG00000163464 ENSG00000186810 ENSG00000111537 ENSG00000163739 ENSG00000026508 ENSG00000162692 PMC3898353__F1 Complement activation pathways ENSG00000274619 ENSG00000039537 ENSG00000113600 ENSG00000291559 ENSG00000203710 ENSG00000000971 ENSG00000166278 PMC3410851__F9 Multiple Roles and Interactions of Tbx4 and Tbx5 in Development of the Respiratory System ENSG00000136158 ENSG00000066468 ENSG00000070193 ENSG00000125398 ENSG00000134245 ENSG00000121075 ENSG00000089225 PMC8522100__F2 Comprehensive analysis of oncogenic fusions in mismatch repair deficient colorectal carcinomas by sequential DNA and RNA next generation sequencing ENSG00000157764 PMC11672291__F7 The potential mechanism by which intracellular PC capsules exert anti‐inflammatory effects by inhibiting apoptosis ENSG00000173599 ENSG00000132478 PMC4232400__F5 E2F2 Transcription Factor Sustains Hepatic Glycerophospholipid Homeostasis in Mice ENSG00000110721 ENSG00000185813 ENSG00000174915 ENSG00000111684 ENSG00000111666 ENSG00000156471 ENSG00000241878 ENSG00000133027 PMC6920321__F2 NFKB Signaling Pathway(Left) Canonical pathway of NFKB activation ENSG00000104856 ENSG00000172936 ENSG00000162924 ENSG00000111321 ENSG00000127191 ENSG00000168610 ENSG00000146648 PMC3815777__F2 Putative intracellular cascades activated by cyclic di‐nucleotides ENSG00000239732 ENSG00000088888 ENSG00000105397 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC4730273__F3 The tryptophan (TRP) metabolic pathway ENSG00000162882 PMC11464522__F2 Molecular mechanism of ferroptosis in RCC ENSG00000147162 ENSG00000151012 ENSG00000197635 ENSG00000163568 ENSG00000103150 ENSG00000127528 ENSG00000079999 ENSG00000168003 ENSG00000128272 ENSG00000167468 ENSG00000155660 ENSG00000111684 ENSG00000115107 ENSG00000142002 PMC11464522__F1 Ferroptosis ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000115107 PMC11464522__F4 Molecular mechanism of ferroptosis in BCa ENSG00000103642 ENSG00000185070 ENSG00000151012 ENSG00000160408 ENSG00000146457 ENSG00000241878 ENSG00000132170 ENSG00000168003 ENSG00000092621 ENSG00000167468 ENSG00000111684 ENSG00000115107 ENSG00000134531 PMC11464522__F3 Molecular mechanism of ferroptosis in PCa ENSG00000129194 ENSG00000151012 ENSG00000198793 ENSG00000112561 ENSG00000103888 ENSG00000168003 ENSG00000111537 ENSG00000101049 ENSG00000092621 ENSG00000115415 ENSG00000167468 ENSG00000111684 ENSG00000115107 ENSG00000139687 ENSG00000104325 PMC7484992__F1 Signaling pathways activated by CXCR4 ENSG00000107562 ENSG00000291971 ENSG00000198793 ENSG00000144476 PMC2860937__F1 Caveat mTOR: aberrant signaling disrupts corticogenesis ENSG00000198793 ENSG00000160469 PMC8533503__F2 Pyrroloquinoline-Quinone Is More Than an Antioxidant: A Vitamin-like Accessory Factor Important in Health and Disease Prevention ENSG00000105835 ENSG00000175567 PMC4302085__F1 Networking of the PI3K/Akt/mTOR signaling pathway ENSG00000138798 ENSG00000198793 ENSG00000164327 ENSG00000146648 ENSG00000140443 PMC3441384__F4 Nanoparticle-induced autophagy ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC2858611__F3 Depiction of the “Reelin signalling in neurons” pathway generated by Ingenuity ENSG00000142192 ENSG00000131089 ENSG00000010810 ENSG00000150093 ENSG00000099942 ENSG00000173406 PMC4302085__F2 Proposed mechanisms accounting for resistance to inhibitors of the PI3K pathway ENSG00000169047 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC6480472__F1 Diagram of microRNAs and their involved pathways to cancer hallmarks ENSG00000169554 ENSG00000163599 ENSG00000198793 ENSG00000047936 ENSG00000168610 ENSG00000146648 ENSG00000026103 PMC8905141__F5 Transcriptomic and Metabolomic Analyses Reveal the Differential Regulatory Mechanisms of Compound Material on the Responses of Brassica campestris to Saline and Alkaline Stresses ENSG00000131473 ENSG00000117118 ENSG00000158104 PMC6714206__F7 Mechanism of PB2 on the protective effect in liver fibrosis ENSG00000112715 ENSG00000128602 PMC2238789__F4 Neuronal pathway containing proteins found in Lewy bodies ENSG00000104327 ENSG00000277586 ENSG00000100285 ENSG00000100906 ENSG00000141458 ENSG00000120885 ENSG00000102003 PMC2238789__F3 Hypothetical ‘super pathway’ not stratified for cell type illustrating known direct interactions between the 892 PD priority genes (regulation, expression and promoter binding only) ENSG00000074317 ENSG00000100285 ENSG00000070831 ENSG00000189056 ENSG00000087085 ENSG00000114948 ENSG00000132639 ENSG00000277586 ENSG00000131089 ENSG00000148408 ENSG00000213023 ENSG00000078053 ENSG00000220205 ENSG00000175426 ENSG00000103769 ENSG00000139970 ENSG00000276996 ENSG00000091140 ENSG00000164949 PMC3571341__F12 Proposed model of M-CSF-mediated organization of the osteoclast cytoskeleton ENSG00000159224 ENSG00000134215 PMC2238789__F2 a Cell processes predicted to be influenced by the top up-regulated priority genes (164 genes showing a differential expression >1 log2) based on in silico analysis employing the ResNet database (PathwayStudio 5.0, Ariadne) ENSG00000178573 ENSG00000123213 ENSG00000189056 ENSG00000283060 PMC7820501__F4 Summary of the molecular processes during COVID-19 infections that are affected in DS ENSG00000169245 ENSG00000140564 ENSG00000115415 ENSG00000130234 ENSG00000184012 ENSG00000135828 PMC2238789__F5 Interactions of known PD genes (marked yellow) with the priority genes of this study ENSG00000127445 ENSG00000074317 ENSG00000163064 ENSG00000102003 ENSG00000154096 PMC12066314__F9 Proposed model showing that apigenin promotes pigmentation through the c-KIT/Raf-1/MAPK/CREB signaling pathway ENSG00000115648 ENSG00000070831 ENSG00000169047 ENSG00000105662 PMC8222328__F4 Identification of biological pathway and process regulators using sparse partial least squares and triple-gene mutual interaction ENSG00000127948 ENSG00000084774 PMC8222328__F2 Identification of biological pathway and process regulators using sparse partial least squares and triple-gene mutual interaction ENSG00000149311 ENSG00000184517 ENSG00000115419 ENSG00000084774 PMC11586126__F4 CLACs are most significantly enriched in neurological pathways, including (A) glutamate receptor signaling pathway and (B) axon guidance signaling pathway ENSG00000043355 ENSG00000183734 ENSG00000122180 ENSG00000151657 ENSG00000156925 ENSG00000185008 PMC3762983__F2 Example of a pathway reconstruction experiment ENSG00000130385 ENSG00000163217 PMC4891133__F7 Sonic hedgehog signaling pathway stimulates anaplastic thyroid cancer cell motility and invasiveness by activating Akt and c-Met ENSG00000164690 ENSG00000128602 PMC7859355__F8 Schematic depiction of our proposed model of the role of ROS in the regulation of FGF2-induced AKT phosphorylation in hPSCs ENSG00000077782 PMC3782205__F2 Nephrin-adaptors complex ENSG00000010810 ENSG00000198087 ENSG00000137672 PMC11007890__F5 Polycomb repressive complex 2 and its core component EZH2: potential targeted therapeutic strategies for head and neck squamous cell carcinoma ENSG00000137673 ENSG00000134982 ENSG00000196591 ENSG00000168610 PMC8051677__F6 Harnessing the Benefits of Neuroinflammation: Generation of Macrophages/Microglia with Prominent Remyelinating Properties ENSG00000131473 ENSG00000178035 ENSG00000167658 ENSG00000131828 ENSG00000103811 ENSG00000173221 ENSG00000117862 ENSG00000004455 ENSG00000100412 ENSG00000113552 ENSG00000163131 ENSG00000271303 ENSG00000118520 ENSG00000075239 ENSG00000146701 ENSG00000141526 ENSG00000126432 ENSG00000117305 ENSG00000062485 PMC9334851__F1 Cross-Activation of Hemichannels/Gap Junctions and Immunoglobulin-Like Domains in Innate–Adaptive Immune Responses ENSG00000177455 ENSG00000165478 ENSG00000186716 ENSG00000117335 ENSG00000110218 PMC6290138__F2 Hypusine–polyamine pathway in human neuroblastoma ENSG00000151224 ENSG00000088826 ENSG00000095059 ENSG00000148832 ENSG00000129932 ENSG00000116649 ENSG00000102172 PMC4164328__F3 Intracellular pathway associated with IGF1R activation ENSG00000197081 ENSG00000198793 ENSG00000140443 PMC4164328__F2 Intracellular pathway associated with GHR activation in hepatocytes ENSG00000112964 ENSG00000146648 PMC8516344__F4 Ventricular voltage‐gated ion channels: Detection, characteristics, mechanisms, and drug safety evaluation PMC8516344__F3 Ventricular voltage‐gated ion channels: Detection, characteristics, mechanisms, and drug safety evaluation ENSG00000136158 ENSG00000198626 PMC7699713__F1 Redox Potential of Antioxidants in Cancer Progression and Prevention ENSG00000132478 PMC8487963__F1 MDS and current therapeutic options ENSG00000187266 PMC7699713__F2 Metabolic regulation of antioxidants: Highly proliferative cancer cells rely on glycolysis to meet its exceedingly high energy demands ENSG00000078237 PMC9356074__F1 NAD+ and its possible role in gut microbiota: Insights on the mechanisms by which gut microbes influence host metabolism ENSG00000105835 ENSG00000291814 ENSG00000123572 ENSG00000008130 PMC4942931__F9 Pathway analysis using IPA software suggests B3-adrenergic receptor signaling activation in T1D-MSCs, with upregulation of several downstream molecules ENSG00000291971 ENSG00000125388 ENSG00000168610 PMC5638116__F3 Targeting the mercapturic acid pathway and vicenin-2 for prevention of prostate cancer ENSG00000017797 ENSG00000284774 ENSG00000070831 ENSG00000138798 ENSG00000198793 ENSG00000136997 ENSG00000146648 PMC5638116__F2 Mechanism of synergistic action of VCN-2 and docetaxel (DTL) ENSG00000134057 ENSG00000135446 ENSG00000132646 ENSG00000164690 ENSG00000146648 ENSG00000140443 PMC8118237__F1 Intracellular and intercellular iron trafficking in the tumor microenvironment ENSG00000111537 ENSG00000151012 ENSG00000119686 ENSG00000026508 PMC6540260__F1 T-cell suppression and immune checkpoint blockage in tumor and organ rejection ENSG00000134982 ENSG00000198793 ENSG00000105639 PMC10669226__F4 Production of Nitric Oxide and Reactive Oxygen Species in Macrophages signaling pathways is predicted to be upregulated in EVPs from aged animals ENSG00000111537 ENSG00000198053 ENSG00000115415 ENSG00000141639 ENSG00000116701 PMC9445052__F7 Inhibition of mTOR in bovine monocyte derived macrophages and dendritic cells provides a potential mechanism for postpartum immune dysfunction in dairy cows ENSG00000177575 ENSG00000150782 ENSG00000081181 ENSG00000111537 ENSG00000198793 ENSG00000184371 ENSG00000164400 ENSG00000113520 ENSG00000113302 ENSG00000168811 ENSG00000007171 PMC11566422__F3 ENO1 and its targeted therapy in tumors ENSG00000091317 ENSG00000074800 ENSG00000137673 ENSG00000198053 ENSG00000291971 ENSG00000026508 ENSG00000168036 ENSG00000078098 PMC11566422__F2 ENO1 and its targeted therapy in tumors ENSG00000074800 ENSG00000137673 ENSG00000026508 ENSG00000168036 PMC5983129__F7 Cisplatin treatment to the induction of apoptosis ENSG00000128272 ENSG00000123374 ENSG00000162772 PMC3942282__F1 The molecular mechanisms and pathways of BBR in reducing oxidative stress and inflammation ENSG00000181019 ENSG00000163914 ENSG00000175567 PMC10669226__F3 Cardiac Hypertrophy Signaling pathway is predicted to be upregulated in EVPs from aged animals ENSG00000162889 ENSG00000198793 ENSG00000163914 ENSG00000169047 ENSG00000177606 ENSG00000108443 ENSG00000281877 PMC2767105__F2 Intracellular ascorbate (Asc) modulates redox-sensitive signaling pathways in microvascular endothelial cells during sepsis ENSG00000111537 ENSG00000115415 ENSG00000125347 PMC2747759__F1 Monoclonal antibodies in the treatment of pancreatic cancer ENSG00000168040 PMC8770286__F2 Crosstalk Among YAP, LncRNA, and Tumor-Associated Macrophages in Tumorigenesis Development ENSG00000181788 ENSG00000196470 ENSG00000150457 ENSG00000131023 PMC8342713__F7 Inhibitory mechanism of APG-1252 and gemcitabine against nasopharyngeal carcinoma ENSG00000168610 PMC8277227__F1 Interplay of DAMPs, TLR4, and proinflammatory cytokines in pulmonary fibrosis ENSG00000125538 ENSG00000189403 ENSG00000172936 PMC5732353__F4 Schematic representation of DAPs associated with theanine (A) and flavonoid (B) biosynthesis ENSG00000117525 ENSG00000145321 ENSG00000115419 PMC5932588__F1 Molecular mechanisms that connect cellular junctions to the Hippo pathway ENSG00000126016 ENSG00000130545 ENSG00000114978 ENSG00000132849 ENSG00000144791 ENSG00000072415 ENSG00000084774 PMC4107103__F6 Hypothetical model of molecular determinants of CLL cell survival, proliferation and migration in the PB, BM and LN microenvironments ENSG00000104856 ENSG00000107562 ENSG00000173039 ENSG00000104921 ENSG00000127191 ENSG00000118971 ENSG00000010671 ENSG00000121966 ENSG00000140379 ENSG00000156127 ENSG00000186716 ENSG00000056558 ENSG00000026508 ENSG00000126353 PMC8533985__F7 Increased Phosphatase of Regenerating Liver-1 by Placental Stem Cells Promotes Hepatic Regeneration in a Bile-Duct-Ligated Rat Model ENSG00000178860 ENSG00000067900 PMC5299404__F4 Mediterranean versus Red sea corals facing climate change, a transcriptome analysis ENSG00000087095 ENSG00000291971 ENSG00000074181 ENSG00000135341 ENSG00000146648 PMC9322955__F3 Molecular Mechanism of Polyphenols with Anti-Aging Activity in Aged Human Dermal Fibroblasts ENSG00000149311 ENSG00000175054 ENSG00000169245 ENSG00000135446 ENSG00000105810 PMC6628600__F5 UPLC-Q-TOF-MS profiling of the hippocampus reveals metabolite biomarkers for the impact of Dl-3-n-butylphthalide on the lipopolysaccharide-induced rat model of depression ENSG00000198793 ENSG00000101280 ENSG00000174946 PMC9322955__F2 Molecular Mechanism of Polyphenols with Anti-Aging Activity in Aged Human Dermal Fibroblasts PMC4117527__F5 Genome-Wide Analysis in Human Colorectal Cancer Cells Reveals Ischemia-Mediated Expression of Motility Genes via DNA Hypomethylation ENSG00000109332 ENSG00000134982 ENSG00000165113 ENSG00000171049 ENSG00000148926 ENSG00000249992 ENSG00000170606 ENSG00000101266 ENSG00000136826 ENSG00000130164 ENSG00000011422 ENSG00000196981 ENSG00000088247 ENSG00000138162 ENSG00000113520 ENSG00000130513 ENSG00000109670 ENSG00000162896 ENSG00000130208 ENSG00000115548 ENSG00000067057 ENSG00000122257 ENSG00000281877 ENSG00000158290 ENSG00000133048 ENSG00000164056 ENSG00000120616 PMC9322955__F1 Molecular Mechanism of Polyphenols with Anti-Aging Activity in Aged Human Dermal Fibroblasts ENSG00000079999 PMC6199368__F5 Hypothetical model to sensitize GC ENSG00000002330 ENSG00000136936 PMC8185927__F1 Overcoming the UCB HSCs –Derived NK cells Dysfunction through Harnessing RAS/MAPK, IGF-1R and TGFB Signaling Pathways ENSG00000291603 ENSG00000174059 PMC11277918__F2 cGAS-STING can transform a cold tumor into a hot tumor and promote tumor cell apoptosis ENSG00000164430 ENSG00000163235 ENSG00000125538 PMC10815231__F5 Graphical summary of the mechanisms of action of microRNAs and lncRNAs in renal fibrosis ENSG00000198793 ENSG00000135605 ENSG00000152556 PMC20445__F6 Schematic diagram showing steps in the signaling pathway by which P ENSG00000108849 ENSG00000291971 ENSG00000001626 PMC8304747__F5 Cisplatin Resistance and Redox-Metabolic Vulnerability: A Second Alteration ENSG00000157064 ENSG00000173614 ENSG00000049768 PMC4359951__F3 Genomic analysis of metastatic cutaneous squamous cell carcinoma ENSG00000019991 ENSG00000157404 ENSG00000005339 ENSG00000157764 ENSG00000100906 ENSG00000148400 ENSG00000198793 ENSG00000149311 ENSG00000175054 ENSG00000186575 ENSG00000105122 ENSG00000135446 ENSG00000136997 ENSG00000105810 ENSG00000139687 ENSG00000146648 ENSG00000178568 ENSG00000196712 ENSG00000198286 PMC8304747__F2 Cisplatin Resistance and Redox-Metabolic Vulnerability: A Second Alteration ENSG00000131473 ENSG00000169710 ENSG00000115419 PMC8730355__F1 Contribution of the cardiomyocyte to tissue inflammation in cardiomyopathies ENSG00000164430 ENSG00000163739 ENSG00000121807 PMC10385272__F5 Key gene expression patterns in carbohydrate metabolism and lipid metabolism pathways in the pulp and seeds of Symplocos paniculate ENSG00000131473 ENSG00000198670 ENSG00000105953 PMC6857099__F4 BRD4 is involved in the transforming growth factor B (TGF-ß)/SMAD signaling pathway ENSG00000141867 PMC10815231__F2 Therapeutic implications of miRNAs and lncRNAs in AKI ENSG00000113384 ENSG00000162711 ENSG00000108691 ENSG00000159216 ENSG00000137275 ENSG00000159399 ENSG00000163349 PMC10815231__F4 Graphical summary of the mechanisms of action of miRNAs and lncRNAs in DKD ENSG00000131914 ENSG00000116406 ENSG00000169213 ENSG00000198793 ENSG00000086991 ENSG00000168610 ENSG00000291368 ENSG00000214253 PMC10815231__F3 Action of ncRNAs in CKD ENSG00000102908 ENSG00000198793 PMC6370815__F7 KEGG cell cycle pathway analysis ENSG00000144063 ENSG00000118007 ENSG00000108055 ENSG00000205250 ENSG00000277273 ENSG00000276876 ENSG00000145604 ENSG00000094804 ENSG00000065833 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000164754 PMC7427467__F5 IL-27 tips the balance of immunity toward L ENSG00000108691 ENSG00000111537 PMC7504502__F3 Feedback loop on BMP4 pathway mediated by miR-125a/b and miR-23a-24-27a during both the exit of mESCs from naïve state and their neuroectodermal differentiation ENSG00000170365 PMC3628288__F2 Diagram of two potential molecular pathways of serrated neoplasia ENSG00000157764 PMC26984__F1 Proposed pathway of EGF-induced cell proliferation of ER− breast cancer cells ENSG00000124102 ENSG00000135446 ENSG00000138798 ENSG00000105810 ENSG00000146648 PMC9608775__F1 MicroRNA-383: A tumor suppressor miRNA in human cancer ENSG00000117724 ENSG00000169554 ENSG00000102317 ENSG00000176887 ENSG00000291803 ENSG00000154134 ENSG00000125347 ENSG00000143155 ENSG00000163507 PMC9189572__F11 Longitudinal intronic RNA-Seq analysis of Parkinson’s disease patients reveals disease-specific nascent transcription ENSG00000123240 ENSG00000128272 ENSG00000177606 ENSG00000112561 ENSG00000166278 PMC6593428__F7 Model describing the mechanism regarding the inhibitory effect of IFITM2 on Type I IFN signaling pathway ENSG00000183735 ENSG00000185201 PMC9189572__F10 Longitudinal intronic RNA-Seq analysis of Parkinson’s disease patients reveals disease-specific nascent transcription ENSG00000291983 ENSG00000128272 ENSG00000100387 ENSG00000113558 ENSG00000127191 ENSG00000198168 PMC8786807__F7 Naringenin Regulates FKBP4/NR3C1/NRF2 Axis in Autophagy and Proliferation of Breast Cancer and Differentiation and Maturation of Dendritic Cell ENSG00000004478 PMC6561916__F4 Stem cell-related signaling pathways in miR-25 overexpressing LX-2 cells ENSG00000112576 ENSG00000141551 ENSG00000154001 ENSG00000196782 ENSG00000160710 ENSG00000143801 ENSG00000168214 ENSG00000074181 ENSG00000163558 ENSG00000136997 ENSG00000169118 ENSG00000196498 ENSG00000108821 ENSG00000077782 ENSG00000087095 ENSG00000166167 ENSG00000148400 ENSG00000180447 ENSG00000112210 ENSG00000026508 ENSG00000119402 ENSG00000140564 ENSG00000107562 ENSG00000070831 ENSG00000050748 ENSG00000170558 ENSG00000175592 ENSG00000101266 ENSG00000118971 ENSG00000130164 ENSG00000163840 ENSG00000184384 ENSG00000283780 ENSG00000196549 ENSG00000205155 ENSG00000165879 ENSG00000100603 ENSG00000027075 ENSG00000005339 ENSG00000178498 ENSG00000175029 ENSG00000277641 ENSG00000090932 ENSG00000106003 ENSG00000091073 ENSG00000078304 ENSG00000133275 ENSG00000067606 ENSG00000177606 ENSG00000161202 ENSG00000128602 ENSG00000114166 PMC4351630__F6 Schematic summary of the effects mediated by RA-NPs against MPTP-induced injury in the dopaminergic (DA) nigrostriatal pathway of adult and old mice ENSG00000107859 PMC9317521__F3 New Insights into Bile Acids Related Signaling Pathways in the Onset of Colorectal Cancer ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC7723503__F8 Signaling pathway of CaOx-induced ferroptosis in HK-2 cells and rat renal tissues ENSG00000168003 ENSG00000151012 ENSG00000167468 PMC8764312__F1 Novel Targets and Therapeutic Strategies to Protect Against Hepatic Ischemia Reperfusion Injury ENSG00000162711 ENSG00000010810 ENSG00000071889 ENSG00000172936 ENSG00000136869 PMC6521546__F5 Superimposing mTOR signaling subgraphs from KEGG and WikiPathways ENSG00000101407 ENSG00000119487 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000175766 ENSG00000213341 ENSG00000141564 ENSG00000167965 ENSG00000187840 PMC3361581__F1 Depiction of arachidonic acid signaling pathway highlighting genes measured in this study ENSG00000108839 ENSG00000161905 ENSG00000122420 ENSG00000050628 ENSG00000160013 ENSG00000125384 ENSG00000168229 ENSG00000095303 ENSG00000275565 ENSG00000073756 ENSG00000160951 PMC6701280__F7 IH protection against liver fibrosis ENSG00000087245 PMC9015122__F2 Interaction types that are not found in ENSG00000196502 PMC5410960__F4 Rb1 pathway ENSG00000135446 ENSG00000139687 PMC7821926__F1 Unfolded protein response (UPR) pathway ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000171791 PMC8066821__F2 Biosynthetic (transsulfuration) and catabolic (oxidation) pathways of H2S ENSG00000137767 ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC8225085__F4 Isolation and Establishment of a Highly Proliferative, Cancer Stem Cell-Like, and Naturally Immortalized Triple-Negative Breast Cancer Cell Line, KAIMRC2 ENSG00000087245 ENSG00000111057 ENSG00000175793 ENSG00000175315 ENSG00000114948 ENSG00000171791 ENSG00000118971 ENSG00000118777 ENSG00000171345 ENSG00000139618 ENSG00000068028 ENSG00000012048 ENSG00000136457 ENSG00000103490 ENSG00000160180 ENSG00000177606 ENSG00000136997 ENSG00000170430 ENSG00000184371 ENSG00000123374 ENSG00000107485 ENSG00000100985 ENSG00000146648 ENSG00000125968 PMC6074780__F1 PD-1 in T-cell activation, exhaustion and effector function.Notes: (A) T-cells are activated via (1) binding of MHC plus peptide on an APC to the TCR and then (2) binding of APC CD80/86 to T-cell CD28 ENSG00000134982 PMC3173057__F11 Schematic view of the proposed HSP60-TLR4 signaling in response to myocardial ischemia ENSG00000172936 ENSG00000136869 ENSG00000168040 ENSG00000184216 PMC2913069__F1 Interconnected pathways that cause bone marrow failure ENSG00000166340 ENSG00000182774 ENSG00000124614 ENSG00000182899 ENSG00000197728 ENSG00000138326 ENSG00000171863 ENSG00000166848 ENSG00000175054 ENSG00000132604 ENSG00000144554 ENSG00000284764 ENSG00000051180 ENSG00000128513 ENSG00000145912 ENSG00000130826 ENSG00000109534 ENSG00000181544 ENSG00000291996 ENSG00000187790 ENSG00000115392 ENSG00000187741 ENSG00000112039 ENSG00000158169 ENSG00000092330 ENSG00000149311 ENSG00000164362 ENSG00000147601 PMC4291754__F4 Cell signaling pathways are allosterically elicited by the activated receptor tyrosine kinase (RTK) ENSG00000150907 PMC7901191__F9 Wnt signaling pathway associated with FZDs ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000133067 ENSG00000168036 ENSG00000196470 ENSG00000100592 ENSG00000095739 ENSG00000100387 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000183579 ENSG00000108375 ENSG00000185269 PMC2583931__F1 Migrating D-loop model of recombination ENSG00000057468 ENSG00000051180 ENSG00000054796 PMC10814950__F8 Key signalling pathways targeted by a combination of PI3Ki (PIK-75) and CDKi (dinaciclib) ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000139687 PMC6347506__F6 Integrative regulation of physiology by histone deacetylase 3 ENSG00000111537 ENSG00000171720 ENSG00000101849 ENSG00000288325 ENSG00000105552 ENSG00000177565 ENSG00000133805 PMC4504805__F1 Schematic of BH4 de novo synthesis, salvage, and regeneration pathways and its role in 5-HT synthesis ENSG00000228716 ENSG00000139287 ENSG00000085662 PMC6347506__F5 Integrative regulation of physiology by histone deacetylase 3 ENSG00000171720 ENSG00000136535 ENSG00000101849 ENSG00000173599 ENSG00000288325 ENSG00000168610 ENSG00000177565 PMC4029488__F2 HFPN model of extended center metabolism pathway in E ENSG00000261701 ENSG00000159224 ENSG00000150787 ENSG00000184207 ENSG00000177084 PMC7723674__F8 Mechanism of action of nimbolide in diethylnitrosamine and N-nitrosomorpholine induced hepatocellular carcinoma mice ENSG00000135446 ENSG00000132646 ENSG00000125538 PMC4029488__F1 Basic regulation mechanisms required in the process of a cell utilizing glucose and glycogen ENSG00000261701 ENSG00000150787 ENSG00000177084 ENSG00000132693 PMC6347506__F2 Integrative regulation of physiology by histone deacetylase 3 ENSG00000171720 ENSG00000101849 ENSG00000117707 ENSG00000288325 ENSG00000177565 PMC3791603__F1 Hh signaling in animals ENSG00000157933 ENSG00000154309 ENSG00000128602 PMC6347506__F4 Integrative regulation of physiology by histone deacetylase 3 ENSG00000171720 ENSG00000105329 ENSG00000101849 ENSG00000160685 ENSG00000138606 ENSG00000288325 ENSG00000177565 PMC7438472__F2 Activation of the AIM2 inflammasome ENSG00000278718 ENSG00000164430 ENSG00000163568 ENSG00000125538 ENSG00000125347 PMC11946830__F2 Hijacking cellular pathways and oncogenic mechanisms in Cryptosporidium infections: Cryptosporidium manipulates several key host cell signaling pathways to ensure its survival and potentially contribute to cancer development ENSG00000070831 ENSG00000134982 ENSG00000140575 ENSG00000173039 ENSG00000136869 ENSG00000167701 PMC5282877__F2 Signaling involved in CSCs that mediates melanoma progression ENSG00000125931 ENSG00000157764 ENSG00000148400 ENSG00000136997 ENSG00000133961 ENSG00000128602 ENSG00000115461 ENSG00000140443 PMC9350720__F1 Complement-mediated microvascular injury and thrombosis in the pathogenesis of severe COVID-19: A review ENSG00000009724 ENSG00000062485 ENSG00000236625 PMC8276946__F2 Molecular mechanisms of aluminum neurotoxicity: Update on adverse effects and therapeutic strategies ENSG00000168040 ENSG00000026103 PMC4054791__F1 Schematic representation of the photorespiratory pathway (in black) and the three circumvent pathways designed to overcome the photorespiratory losses ENSG00000166278 PMC7360684__F2 Canonical TGFB signaling pathway and TGFB signaling targeting therapies ENSG00000137834 ENSG00000136997 PMC3708179__F8 Enrichment of hyper- and hypophosphorylated peptides in the ERK/MAPK signaling pathway in the phosphoproteome of murine liver on treatment with high-fat versus low-fat diet ENSG00000172680 ENSG00000002330 ENSG00000291971 ENSG00000010810 ENSG00000136997 ENSG00000131196 PMC4678324__F3 Cell-intrinsic versus cell-extrinsic control of metastatic progression by miRNAs ENSG00000153208 ENSG00000154217 ENSG00000115457 ENSG00000140403 ENSG00000140443 ENSG00000156273 PMC4783254__F2 Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease ENSG00000167468 PMC2896712__F2 Metabolic pathway map constructed using the E-Cell RBC model ENSG00000111341 ENSG00000184207 PMC2744640__F4 Regulation of Mitochondrial Respiratory Chain Biogenesis by Estrogens/Estrogen Receptors and Physiological, Pathological and Pharmacological Implications ENSG00000096088 ENSG00000185591 ENSG00000106459 PMC11087094__F3 Four most related metabolic pathways in digestive system tumors ENSG00000173599 ENSG00000118520 ENSG00000036473 ENSG00000169154 ENSG00000115419 PMC8397173__F8 Histidine Kinase Sln1 and cAMP/PKA Signaling Pathways Antagonistically Regulate Sporisorium scitamineum Mating and Virulence via Transcription Factor Prf1 ENSG00000180644 ENSG00000123268 PMC5391460__F9 NEAT1 exerts antihantaviral effects by acting as positive feedback for RIG-I signaling ENSG00000088888 ENSG00000131323 ENSG00000276561 PMC3242749__F4 Idebenone and Resveratrol Extend Lifespan and Improve Motor Function of HtrA2 Knockout Mice ENSG00000128272 ENSG00000171791 ENSG00000115317 PMC3140140__F1 Variation in the suppressive abilities of Wnt antagonists with respect to canonical and non-canonical Wnt signaling pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC4312948__F7 Role of TRP channels in the vascular system ENSG00000092439 ENSG00000104321 ENSG00000144935 ENSG00000069018 ENSG00000137672 ENSG00000138741 ENSG00000196689 PMC7503523__F2 Polyomavirus JC: one virus, two stories ENSG00000149311 ENSG00000175054 ENSG00000186575 ENSG00000134982 ENSG00000169047 ENSG00000136997 ENSG00000168036 ENSG00000051180 ENSG00000140464 ENSG00000140443 PMC8969174__F1 Genetic architecture of childhood BMI exhibits dynamic changes over early childhood ENSG00000266265 ENSG00000135472 ENSG00000131096 ENSG00000112038 ENSG00000173442 ENSG00000009950 ENSG00000138193 ENSG00000164161 ENSG00000175426 ENSG00000196498 ENSG00000166603 ENSG00000160360 ENSG00000291608 ENSG00000132535 ENSG00000215529 ENSG00000118420 ENSG00000163660 ENSG00000120341 PMC9235413__F5 Site of action of the Wnt signaling pathway inhibitors that are in current or were in past clinical trials ENSG00000162337 ENSG00000134982 ENSG00000102312 ENSG00000168036 PMC9235413__F3 Crosstalk between Wnt and other major signaling pathways in uterine fibrosis ENSG00000281324 ENSG00000162337 ENSG00000198793 ENSG00000168036 ENSG00000133961 PMC9235413__F2 Wnt signaling in mechanotransduction and extracellular matrix (ECM) alterations in uterine fibrosis ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9235413__F1 Canonical and noncanonical Wnt signaling pathways ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000070831 ENSG00000134982 ENSG00000163914 ENSG00000177606 ENSG00000168036 PMC7349809__F1 Mechanisms for respiratory syncytial virus (RSV) inhibition of type I interferon (IFN) production ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000107201 ENSG00000131323 ENSG00000276561 ENSG00000142166 PMC6275424__F1 Ras/ERK signal transduction pathway with emphasis on p120-RasGAP interactions ENSG00000071564 ENSG00000169291 ENSG00000157764 ENSG00000163914 ENSG00000164107 ENSG00000155903 PMC2667382__F8 Phosphorylation of the Translation Initiation Factor eIF2A Increases BACE1 Levels and Promotes Amyloidogenesis ENSG00000144895 PMC8898246__F2 Where are we in 2021 with heart failure with reduced ejection fraction?—current outlook and expectations from new promising clinical trials ENSG00000140564 ENSG00000096088 ENSG00000145244 ENSG00000120937 PMC2976339__F5 Gene expression within cluster MCL2 is enriched in genes affecting NK cell-mediated cytotoxicity ENSG00000169291 ENSG00000291603 ENSG00000213658 ENSG00000154059 ENSG00000164305 ENSG00000026103 PMC8402548__F1 Analysis of Host Immunological Response of Adenovirus-Based COVID-19 Vaccines ENSG00000115266 PMC8089370__F1 Targeting SLC1A5 and SLC3A2/SLC7A5 as a Potential Strategy to Strengthen Anti-Tumor Immunity in the Tumor Microenvironment ENSG00000168003 ENSG00000128272 ENSG00000073350 ENSG00000166402 ENSG00000060138 ENSG00000103257 PMC11087094__F4 Three greatly important metabolic pathways in digestive system tumors ENSG00000086696 ENSG00000173599 ENSG00000179142 ENSG00000172482 ENSG00000184207 ENSG00000176387 ENSG00000062485 PMC11762646__F6 microRNAs regulate pathways by targeting multiple genes ENSG00000167910 ENSG00000169047 ENSG00000185591 ENSG00000115461 PMC5767248__F3 AMPAR trafficking during Alzheimer’s disease (AD): early and later phases ENSG00000010810 ENSG00000102172 PMC8481958__F1 Immunometabolism during inflammaging ENSG00000162711 ENSG00000125538 ENSG00000198793 ENSG00000184344 PMC4608483__F2 RNR regulation in S PMC6755339__F2 Main synthesis pathway of n-3 long-chain PUFA-derived lipid mediators ENSG00000170775 ENSG00000171049 PMC8837022__F3 Isoxazole Derivative of Usnic Acid Induces an ER Stress Response in Breast Cancer Cells That Leads to Paraptosis-like Cell Death ENSG00000291983 ENSG00000128272 ENSG00000100387 ENSG00000113558 ENSG00000188404 ENSG00000126261 ENSG00000171791 ENSG00000127191 ENSG00000198168 PMC3080176__F2 Diagrammatic representation of the top three canonical signaling pathways, proposed by the Ingenuity Pathways Analysis program, associated with differentially expressed genes in the microarray dataset ENSG00000149311 ENSG00000177084 ENSG00000155657 PMC5372523__F1 Nerve growth factor (NGF) and its Tyrosine Kinase A receptor (TRKA) are involved in several signaling pathways in epithelial ovarian cancer (EOC) PMC7990367__F3 Pathways regulating cellular senescence and the SASP ENSG00000149311 ENSG00000175054 ENSG00000115008 ENSG00000164430 ENSG00000285109 ENSG00000115415 ENSG00000056972 ENSG00000198793 ENSG00000096717 ENSG00000168610 PMC11642960__F4 Pathway and network analysis of the proteins identified in the AR/SRF interactome ENSG00000004478 ENSG00000105401 ENSG00000135446 ENSG00000111837 ENSG00000164362 ENSG00000168036 ENSG00000129514 ENSG00000106546 ENSG00000141456 PMC7963155__F4A MicroRNAs in the Cisplatin- and Radio-Resistance of Cervical Cancer PMC11642960__F6 Proposed common pathways of the SRF/AR interactome and the key proteins identified by APMS and bioinformatics ENSG00000188229 ENSG00000104833 ENSG00000132341 ENSG00000141456 PMC4860161__F1 Autophagy pathway ENSG00000177169 ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC4018747__F4 Pathways leading from ssDNA-bound RPA to the recruitment of an error-prone polymerase η, ι, K or Rev1 for bypass of a potential template lesion ENSG00000175054 ENSG00000164053 ENSG00000101751 ENSG00000132646 ENSG00000070950 ENSG00000130997 ENSG00000122008 PMC9147761__F1 Biomarkers of Cancer Stem Cells for Experimental Research and Clinical Application ENSG00000168283 ENSG00000119888 ENSG00000140044 PMC2721253__F2 Modes of neurite growth inhibition of molecules expressed on CNS myelin and oligodendrocytes ENSG00000143013 ENSG00000163914 ENSG00000169783 PMC107042__F1 Diagram showing the relationships among the regulatory factors governing srf transcription initiation ENSG00000105664 PMC6563036__F3 Proposed mechanism between mTOR Signaling Pathway, Inhibitors and Photodynamic Therapy (PDT) ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC6563036__F2 mTOR Signaling pathway ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC5860060__F4 Association network of linc-RPIA identified in co-module 1 ENSG00000005339 ENSG00000070182 ENSG00000291971 ENSG00000161203 ENSG00000010017 ENSG00000141564 ENSG00000100485 ENSG00000092820 ENSG00000038382 ENSG00000182175 ENSG00000084676 ENSG00000188157 ENSG00000186716 ENSG00000196935 ENSG00000196498 ENSG00000133961 ENSG00000118257 ENSG00000185008 ENSG00000146648 PMC2822437__F1 Heterotrimeric G Proteins and Apoptosis: Intersecting Signaling Pathways Leading to Context Dependent Phenotypes ENSG00000168040 PMC4744573__F1 Standing your Ground to Exoribonucleases: Function of Flavivirus Long Non-coding RNAs ENSG00000144535 ENSG00000114127 ENSG00000172795 PMC8041604__F4 Mechanisms of PI3K/Akt/mTOR pathway and MAPK pathway, and inhibitors in ovarian cancer clinical development ENSG00000002330 ENSG00000070831 ENSG00000156299 ENSG00000198793 ENSG00000171540 PMC10538272__F5 Irreversible repolarization of tumour‐associated macrophages by low‐Pi stress inhibits the progression of hepatocellular carcinoma ENSG00000102970 ENSG00000172936 ENSG00000126353 PMC11959054__F7 Role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout ENSG00000115415 ENSG00000172936 ENSG00000168610 PMC8699560__F1 Enhancing Therapeutic Approaches for Melanoma Patients Targeting Epigenetic Modifiers ENSG00000094631 ENSG00000163599 PMC2865177__F1 ER stress-induced apoptotic pathways ENSG00000128272 ENSG00000197930 ENSG00000144895 ENSG00000171791 ENSG00000127191 PMC8541136__F1 Heparanase Regulatory Network in Health and Disease ENSG00000118972 ENSG00000019991 ENSG00000157764 ENSG00000125538 ENSG00000173083 ENSG00000136869 ENSG00000185591 PMC6721072__F5 Ca2+ toolkit in endothelial colony forming cells (ECFC) ENSG00000144935 ENSG00000167323 ENSG00000293604 ENSG00000138741 ENSG00000196689 ENSG00000137841 PMC7516134__F1 Zoledronic acid on the bone metastatic niche and the “vicious cycle of bone metastases” ENSG00000107562 ENSG00000125538 ENSG00000121966 PMC6721072__F2 Ca2+-dependent activation of the extracellular signal-regulated kinase (ERK) pathway and of the Nuclear Factor of Activated T-cells (NFAT) ENSG00000171105 ENSG00000133107 ENSG00000293604 ENSG00000124181 ENSG00000138741 PMC8391121__F1 Invadopodia, a Kingdom of Non-Receptor Tyrosine Kinases ENSG00000169750 ENSG00000291971 ENSG00000138798 ENSG00000160293 ENSG00000146648 PMC6721072__F1 Pro-angiogenic Ca2+ toolkit in vascular endothelial cells ENSG00000171105 ENSG00000133107 ENSG00000144935 ENSG00000167323 ENSG00000293604 ENSG00000149782 ENSG00000137672 ENSG00000182621 ENSG00000124181 ENSG00000138741 ENSG00000137841 ENSG00000101333 PMC8262160__F6 Knockdown of GPSM1 Inhibits the Proliferation and Promotes the Apoptosis of B-Cell Acute Lymphoblastic Leukemia Cells by Suppressing the ADCY6-RAPGEF3-JNK Signaling Pathway ENSG00000174233 ENSG00000160360 PMC12207805__F8 Proposed mechanism by which L-Phe promotes liver steatosis ENSG00000198793 PMC7664917__F2 Signaling pathways in ferroptosis ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000115419 PMC2854301__F9 The Transcriptional Repressor REST/NRSF modulates Hedgehog Signaling ENSG00000084093 ENSG00000164690 PMC6801086__F8 Base excision repair pathway, homologous recombination pathway, and how BER intermediates may lead to HR ENSG00000012048 ENSG00000039650 ENSG00000130997 ENSG00000051180 ENSG00000177084 ENSG00000122008 ENSG00000139618 PMC3656715__F1 Hippocampal BDNF/TrkB signaling pathways that modulate depressive behavior and antidepressant responses ENSG00000070831 ENSG00000198793 ENSG00000168036 PMC7306092__F3 Progression of fibrosis caused by expression of ECM proteins after activation of TSP-1 ENSG00000135218 ENSG00000163914 PMC8186467__F2 Bidirectional Relationship Between Cancer Epigenetics and Metabolism ENSG00000168003 ENSG00000117713 ENSG00000163930 ENSG00000151012 ENSG00000060982 PMC7306092__F2 Activation of pathways triggered by hyperglycemia to induce TSP-1 expression ENSG00000185591 PMC7276297__F1 Biochemical pathway of steroidogenesis ENSG00000172893 ENSG00000179142 PMC7465134__F1 miRNA modulators of the p53 signaling pathway in Adrenocortical Carcinoma ENSG00000132906 ENSG00000164305 PMC10177463__F3 BRAF V600-Mutated Metastatic Melanoma and Targeted Therapy Resistance: An Update of the Current Knowledge ENSG00000019991 ENSG00000137713 ENSG00000198793 ENSG00000196712 ENSG00000107581 PMC5215973__F2 Deubiquitinases in breast cancer ENSG00000135655 ENSG00000152348 ENSG00000134982 ENSG00000036672 ENSG00000173039 ENSG00000168036 ENSG00000116717 ENSG00000158169 ENSG00000155313 ENSG00000134574 ENSG00000090686 ENSG00000083799 ENSG00000026103 ENSG00000122008 PMC7465134__F3 miRNA modulators of the Wnt/Beta-catenin signaling pathway in Adrenocortical Carcinoma ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC7465134__F2 miRNA modulators of the mTOR signaling pathway in Adrenocortical Carcinoma ENSG00000281324 ENSG00000162337 ENSG00000198793 ENSG00000146648 PMC9524263__F4 Melatonin pretreatment on exosomes: Heterogeneity, therapeutic effects, and usage ENSG00000096717 ENSG00000168610 PMC8044947__F1 Popular signaling pathway in the research of primary mediastinal large B-cell lymphoma ENSG00000273686 ENSG00000196396 PMC8033456__F1 STING and transplantation: can targeting this pathway improve outcomes? ENSG00000183735 ENSG00000164430 ENSG00000134982 ENSG00000163599 PMC6721734__F6 Molecular interplay between estrogen, EGF, and Notch signaling pathways in FTEC ciliogenesis ENSG00000129654 ENSG00000138798 ENSG00000146648 PMC8924130__F4 Glioma: molecular signature and crossroads with tumor microenvironment ENSG00000108691 ENSG00000135446 ENSG00000111837 ENSG00000198793 ENSG00000170430 ENSG00000105810 ENSG00000121807 ENSG00000146648 ENSG00000139687 ENSG00000196712 PMC8924130__F3 Glioma: molecular signature and crossroads with tumor microenvironment ENSG00000198793 ENSG00000170430 ENSG00000146648 PMC3937510__F2 Canonical Wnt signaling () ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC7824196__F2 Autophagy regulation by the mTOR signaling pathway ENSG00000177169 ENSG00000092439 ENSG00000198793 ENSG00000096717 PMC7824196__F1 Different steps of autophagy ENSG00000177169 ENSG00000188554 ENSG00000123395 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC2819754__F2 Transcriptional regulation of the differentiation of Th2 cells ENSG00000134982 ENSG00000107485 ENSG00000113520 PMC2819754__F1 Transcriptional regulation of the differentiation of Th1 cells ENSG00000138378 ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000134982 PMC6257326__F2 Network view of associated proteins created within Ingenuity Pathway Analysis software for visualizing molecular interrelationships ENSG00000215021 ENSG00000173221 ENSG00000142192 ENSG00000187608 ENSG00000115415 ENSG00000269335 ENSG00000126457 ENSG00000131095 ENSG00000168398 ENSG00000230034 PMC8156203__F3 Targeting Reactive Oxygen Species Metabolism to Induce Myeloma Cell Death ENSG00000092621 ENSG00000135069 ENSG00000146733 ENSG00000115419 ENSG00000159399 ENSG00000164778 PMC7552066__F4 JAK/STAT signalling pathway ENSG00000213928 ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000105639 ENSG00000168610 ENSG00000146648 PMC7552066__F6 HPV modulation of the STAT3 signalling pathway ENSG00000105397 ENSG00000105639 ENSG00000168610 ENSG00000146648 PMC5882332__F3 Signaling lymphocytic activation molecules Slam and cancers: friends or foes? ENSG00000138798 ENSG00000198793 ENSG00000166851 PMC7509487__F2 How a miRNA affects cellular function: Left, repression of one critical mRNA by an individual miRNA determines cell function ENSG00000138166 PMC3401939__F1 Targeting of oncogenes and miRNAs by retroviruses ENSG00000172680 ENSG00000291971 ENSG00000136997 ENSG00000137193 PMC7830227__F2 Targeting the Hippo signaling pathway ENSG00000136807 ENSG00000141867 ENSG00000131023 PMC213796__F7 EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer ENSG00000074266 ENSG00000178691 PMC2386416__F1 Illustrations of the 5 Alpha-reductase action and the pathway of androgen action on target gene expression ENSG00000163235 ENSG00000138798 PMC7830227__F1 Hippo signaling pathway in mammalian cells ENSG00000129474 ENSG00000131023 PMC7177258__F5 JNK signaling in the stem cell niche ENSG00000041982 ENSG00000118785 ENSG00000189403 PMC7177258__F1 Regulatory system of the C-JUN N-terminal kinase (JNK) signaling cascade ENSG00000141503 ENSG00000130522 ENSG00000099942 PMC8909726__F6 Translational Regulation by hnRNP H/F Is Essential for the Proliferation and Survival of Glioblastoma ENSG00000162607 ENSG00000169813 ENSG00000100985 PMC7177258__F3 JNK signaling in normal stem cells ENSG00000154342 ENSG00000168646 PMC8807551__F7 FGFC1 Selectively Inhibits Erlotinib-Resistant Non-Small Cell Lung Cancer via Elevation of ROS Mediated by the EGFR/PI3K/Akt/mTOR Pathway ENSG00000198793 ENSG00000146648 PMC7073129__F2 Schematic demonstration of the inhibition of the RAR pathway by BMS ENSG00000162337 ENSG00000134245 PMC7073129__F1 Interactions between retinoid signaling and the Wnt/Beta-catenin pathway on the cellular level for growth plate chondrocytes during endochondral ossification ENSG00000139219 ENSG00000125398 ENSG00000162337 ENSG00000168036 PMC7430027__F7 KEGG pathway classification map of the experimental group ENSG00000177455 ENSG00000103479 ENSG00000136457 ENSG00000135218 ENSG00000002330 ENSG00000168743 ENSG00000110799 ENSG00000198793 ENSG00000026508 ENSG00000171791 PMC7230796__F1 Metabolic pathway of vitamin D (based on Jenkinson 2019 and on Feldman et al ENSG00000111012 ENSG00000172893 ENSG00000019186 ENSG00000186104 ENSG00000135929 PMC6290262__F1 UPR activation ENSG00000128272 ENSG00000100219 PMC5819363__F1 Genomic Landscape of Pheochromocytoma and Paraganglioma ENSG00000135956 ENSG00000134086 ENSG00000136997 ENSG00000168036 ENSG00000128602 ENSG00000146701 ENSG00000064300 ENSG00000009307 ENSG00000196712 PMC10920911__F4 Lipid metabolic reprogramming on CRC ENSG00000162711 ENSG00000125538 ENSG00000198670 ENSG00000026652 ENSG00000168610 ENSG00000026103 PMC9407613__F2 New Insights into the Functions of MicroRNAs in Cardiac Fibrosis: From Mechanisms to Therapeutic Strategies ENSG00000140564 ENSG00000185591 PMC10920911__F3 Glucose metabolic reprogramming on CRC ENSG00000265972 ENSG00000168610 PMC3236061__F5 Cooperation of the genes in the DNA repair cluster ENSG00000143799 ENSG00000134982 ENSG00000165280 ENSG00000112118 ENSG00000073111 ENSG00000035928 ENSG00000064933 ENSG00000112312 ENSG00000012048 ENSG00000175054 ENSG00000113456 ENSG00000186575 ENSG00000276618 ENSG00000101773 ENSG00000132383 ENSG00000139372 ENSG00000051180 ENSG00000149806 ENSG00000185515 ENSG00000197275 ENSG00000092330 ENSG00000119048 ENSG00000139618 ENSG00000149311 ENSG00000094804 ENSG00000198576 ENSG00000164362 ENSG00000197299 ENSG00000005381 ENSG00000095002 ENSG00000132341 ENSG00000009413 PMC6305530__F1 Hepatitis C virus-induced inflammation ENSG00000162711 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC11608335__F1 Using Z. mobilis as the chassis for biochemical production ENSG00000197429 ENSG00000100842 ENSG00000166278 ENSG00000158125 PMC9394702__F3 miRNAs as Biomarkers and Possible Therapeutic Strategies in Synovial Sarcoma ENSG00000168036 PMC7239885__F3 Calcium signalling pathway enriched by 48 downregulated genes encoding 23 proteins marked by stars ENSG00000182533 ENSG00000130528 ENSG00000156026 ENSG00000186716 PMC7397015__F1 Summary of experimental approaches used in identification of major mTOR signaling components ENSG00000177058 ENSG00000198793 ENSG00000145979 ENSG00000052795 ENSG00000155792 ENSG00000164327 ENSG00000111737 PMC10473100__F1 Necroptosis and Alzheimer’s Disease: Pathogenic Mechanisms and Therapeutic Opportunities ENSG00000092439 ENSG00000137275 ENSG00000115415 ENSG00000102871 ENSG00000172936 ENSG00000136869 ENSG00000168040 ENSG00000168404 ENSG00000064012 ENSG00000285379 ENSG00000135517 ENSG00000164342 PMC9158378__F1 Sonic hedgehog signaling pathway is susceptible to both genetic and environmental dysregulation ENSG00000064309 ENSG00000180447 ENSG00000144857 ENSG00000154309 ENSG00000164690 ENSG00000128602 PMC6872739__F7 Differential statin effect on cytokine production of monocytes or macrophages is mediated by differential geranylgeranylation-dependent Rac1 activation ENSG00000177575 ENSG00000153208 ENSG00000125538 ENSG00000203710 PMC10473100__F3 Necroptosis and Alzheimer’s Disease: Pathogenic Mechanisms and Therapeutic Opportunities ENSG00000281879 ENSG00000168404 ENSG00000285379 PMC7909827__F3 Paracrine interaction between Beta-cells and D-cells ENSG00000158290 ENSG00000291507 ENSG00000198838 ENSG00000167986 ENSG00000152804 ENSG00000157005 ENSG00000178473 PMC7909827__F2 Nutrient-secretion coupling in D-cells ENSG00000069482 ENSG00000198838 ENSG00000157005 PMC6668790__F6 Defects of mitochondrial RNA turnover lead to the accumulation of double-stranded RNA in vivo ENSG00000107951 ENSG00000119705 PMC4555078__F1 RTK signaling pathways and representative regulatory microRNAs ENSG00000135446 ENSG00000198793 ENSG00000177606 ENSG00000105810 ENSG00000146648 PMC6393639__F6 Olaparib induced senescence under P16 or P53 dependent manner in ovarian cancer ENSG00000112576 ENSG00000135446 ENSG00000105810 PMC2949191__F6 Scheme outlining the novel role of Nogo-A in controlling neuronal survival in the ischemic brain PMC6813780__F2 Genomics of Apicomplexan Parasites ENSG00000069482 PMC4833551__F1 Pathways involved in physiological and in pathological cardiac hypertrophy actuated in calcific aortic valve disease (CAVD) ENSG00000198793 PMC7730145__F3 Novel strategy to facilitate neuronal Cl− extrusion and EGABA by coincident NKCC1 inhibition and KCC2 activation by inhibiting the WNK-SPAK/OSR1 kinases ENSG00000196632 ENSG00000143867 ENSG00000060237 PMC7552066__F7 HPV modulation of the STAT5 signalling pathway ENSG00000105397 ENSG00000105639 ENSG00000146648 ENSG00000292332 ENSG00000121440 ENSG00000109670 PMC8795890__F3 Action of Mesenchymal Stem Cell-Derived Exosomes in the Intervertebral Disc Degeneration Treatment and Bone Repair and Regeneration ENSG00000178860 ENSG00000150782 ENSG00000125398 ENSG00000128917 ENSG00000148400 ENSG00000198793 ENSG00000168036 PMC9604206__F2 Molecular Targets in Osteosarcoma Treatment ENSG00000184916 ENSG00000137845 ENSG00000146648 PMC8795890__F2 Action of Mesenchymal Stem Cell-Derived Exosomes in the Intervertebral Disc Degeneration Treatment and Bone Repair and Regeneration ENSG00000162711 ENSG00000002330 ENSG00000125398 ENSG00000149968 ENSG00000156273 PMC9371363__F2 Negative and positive regulators of IL-4 and IL-13 signaling: ENSG00000143799 ENSG00000105397 ENSG00000169047 ENSG00000131724 ENSG00000118520 ENSG00000105639 ENSG00000175104 ENSG00000168610 ENSG00000163702 PMC9371363__F1 Canonical and non-canonical IL-4 and IL-13 signaling pathways: ENSG00000124102 ENSG00000123496 ENSG00000105397 ENSG00000291971 ENSG00000169047 ENSG00000105639 ENSG00000168610 PMC5161243__F7 Downregulation of a GPCR by Beta-Arrestin2-mediated Switch from an Endosomal to a TGN Recycling Pathway ENSG00000159224 ENSG00000010310 PMC7432778__F6 IL-17A has two receptor complexes, IL-17RA/IL-17RC and IL-17RA/IL-17RD, in keratinocytes ENSG00000163207 ENSG00000175104 ENSG00000143631 ENSG00000163702 PMC5833450__F6 Melatonin-induced signaling pathway ENSG00000291507 ENSG00000173599 ENSG00000158517 ENSG00000171791 ENSG00000057663 PMC7674767__F1 Extrinsic and intrinsic pathways to apoptosis ENSG00000100290 ENSG00000002330 ENSG00000120868 ENSG00000135116 ENSG00000104081 PMC7790578__F9 KEGG pathway details identified by FB against COPD ENSG00000149311 ENSG00000175054 ENSG00000105656 ENSG00000168040 ENSG00000026103 PMC5735114__F2 Distribution of differentially expressed genes in astrocytes following hypoxia+ hypothermia vs ENSG00000043355 ENSG00000087095 ENSG00000180447 ENSG00000112210 ENSG00000095739 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000185269 ENSG00000128602 PMC6599034__F2 Label propagation defines signaling networks associated with recurrently mutated cancer genes ENSG00000149311 ENSG00000175054 ENSG00000169621 ENSG00000291507 ENSG00000065526 ENSG00000170558 ENSG00000198793 ENSG00000136997 ENSG00000164362 ENSG00000166851 ENSG00000166169 ENSG00000122678 PMC8131521__F2 C9ORF72: What It Is, What It Does, and Why It Matters ENSG00000177169 ENSG00000123395 ENSG00000164430 ENSG00000167461 ENSG00000112561 ENSG00000283741 PMC8776063__F13 Aurora Kinase A Is Involved in Controlling the Localization of Aquaporin-2 in Renal Principal Cells ENSG00000167580 ENSG00000087586 ENSG00000084112 PMC7014170__F5 Schematic model illustrating the signaling pathway by which ANG reduces the inflammatory responses involving Myd88 and the nuclear translocation of NFKB in LPS induced EIU ENSG00000125538 ENSG00000113520 ENSG00000172936 ENSG00000136869 PMC12179876__F1 Action and potential therapeutic targets of TGF-Beta-related signaling pathway and its downstream miRNA expression in pulmonary arterial hypertension PMC6298946__F1 IL-20 receptor cytokines and their receptors ENSG00000142677 ENSG00000162892 ENSG00000174564 ENSG00000142224 PMC8718573__F3 Abnormal sialylation and fucosylation of saliva glycoproteins: Characteristics of lung cancer-specific biomarkers ENSG00000125266 ENSG00000157404 ENSG00000198793 ENSG00000101280 ENSG00000110680 ENSG00000273686 ENSG00000081051 ENSG00000062524 ENSG00000104368 ENSG00000081026 ENSG00000132646 ENSG00000137672 ENSG00000146648 PMC2553363__F2 ER stress pathway ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC2553363__F1 Extrinsic and intrinsic pathways of hepatocyte apoptosis ENSG00000002330 PMC9197809__F1 Research progress on drugs targeting the TGFB signaling pathway in fibrotic diseases ENSG00000070831 ENSG00000163914 ENSG00000076604 PMC5297047__F6 The G-protein, cAMP/PKA signaling alterations found in the ZMEL-R1 cells ENSG00000291971 ENSG00000125388 ENSG00000168610 PMC6598629__F1 The supraspinal locomotor network ENSG00000173599 PMC9322890__F14 Recent Advances Regarding the Molecular Mechanisms of Triterpenic Acids: A Review (Part I) ENSG00000132906 ENSG00000138798 ENSG00000198793 ENSG00000120868 ENSG00000146648 ENSG00000164305 PMC4747023__F3 Unique genetic and epigenetic mechanisms driving signatures of paediatric diffuse high-grade glioma ENSG00000157764 ENSG00000134853 ENSG00000121879 ENSG00000077782 ENSG00000140443 PMC4090903__F2 TLR4 intracellular signaling cascade ENSG00000169245 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000184216 PMC9387879__F1 Remarkable Roles of the Receptor for Advanced Glycation End Products (RAGE) and Its Soluble Isoforms in COVID-19: The Importance of RAGE Pathway in the Lung Injuries ENSG00000189403 ENSG00000168610 PMC6152442__F1 SRSF1 regulates SUMO conjugation to different spliceosomal proteins ENSG00000144028 ENSG00000277707 ENSG00000100410 ENSG00000115128 ENSG00000163714 ENSG00000109606 ENSG00000145833 ENSG00000117360 ENSG00000179950 ENSG00000063244 ENSG00000274442 ENSG00000125870 ENSG00000085872 ENSG00000101161 ENSG00000131876 ENSG00000115524 ENSG00000099995 ENSG00000077312 ENSG00000128602 PMC5010983__F1 The (A) Wnt/Beta-catenin, (B) AKT/mTOR, (C) ERK/MAPK signaling networks that are important for oligodendrocyte development and myelination ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000169047 ENSG00000198793 ENSG00000168036 ENSG00000164327 PMC9322890__F11 Recent Advances Regarding the Molecular Mechanisms of Triterpenic Acids: A Review (Part I) ENSG00000162711 ENSG00000239732 ENSG00000125538 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000079999 PMC9322890__F10 Recent Advances Regarding the Molecular Mechanisms of Triterpenic Acids: A Review (Part I) ENSG00000138798 ENSG00000198793 ENSG00000129514 PMC9658772__F2 E3 Ligases in Cervical Cancer and Endometrial Cancer ENSG00000145604 ENSG00000167207 ENSG00000133606 ENSG00000122257 ENSG00000168036 ENSG00000108375 ENSG00000022267 ENSG00000146648 ENSG00000141569 PMC6728366__F7 The PCP and Wnt pathways act in parallel to establish coordinated hair cell polarity and orientation in the neuromast ENSG00000076716 PMC9503233__F1 Gut Non-Bacterial Microbiota: Emerging Link to Irritable Bowel Syndrome ENSG00000162711 ENSG00000187796 ENSG00000172936 ENSG00000136869 PMC4992866__F11 Quantitative phosphoproteomics reveals the role of the AMPK plant ortholog SnRK1 as a metabolic master regulator under energy deprivation ENSG00000288145 ENSG00000197746 PMC3499531__F6 Transcriptome Sequencing and Annotation for the Jamaican Fruit Bat (Artibeus jamaicensis) ENSG00000153487 ENSG00000170369 ENSG00000169750 PMC10382028__F1 Plant-derived extracts and metabolic modulation in leukemia: a promising approach to overcome treatment resistance ENSG00000107562 ENSG00000067057 ENSG00000132646 ENSG00000198793 ENSG00000177606 ENSG00000121966 PMC3470040__F1 MYCN-dependent apoptosis and the MDM2–p53 pathway ENSG00000168283 ENSG00000064393 PMC6040253__F1 Schematic model of the regulation of the Nrf2 signaling pathway ENSG00000181019 ENSG00000178573 ENSG00000100387 ENSG00000079999 PMC3034442__F3 Glycine synthesis and degradation ENSG00000291958 ENSG00000145020 ENSG00000091140 ENSG00000178445 PMC2677061__F1 Postnatal Roles of GDNF Family Members in Nociceptors Plasticity ENSG00000146013 PMC6947889__F7 Induction of pyroptosis via ER stress and the effects of SIRT1 on this process ENSG00000128272 ENSG00000144895 ENSG00000096717 PMC5979320__F2 BCAAs balance and its multiple roles via PI3K-AKT-mTOR signaling pathway ENSG00000101407 ENSG00000169047 ENSG00000198793 ENSG00000155792 ENSG00000164327 PMC11849169__F1 Pathway for triterpenoid saponin biosynthesis in S ENSG00000197429 PMC11876490__F3 Enrichment by Gene Ontology (GO) and pathway terms were visualized using the ClueGO/CluePedia plugin from Cytoscape ENSG00000100220 ENSG00000221914 ENSG00000104413 ENSG00000203485 ENSG00000198380 ENSG00000159720 ENSG00000138663 ENSG00000168090 ENSG00000184260 ENSG00000114503 ENSG00000084733 ENSG00000134440 ENSG00000111540 ENSG00000277401 ENSG00000197081 ENSG00000246705 ENSG00000072756 ENSG00000143376 ENSG00000273213 ENSG00000169756 ENSG00000144744 ENSG00000121390 ENSG00000069329 ENSG00000288859 ENSG00000124802 ENSG00000181029 ENSG00000276368 ENSG00000101811 ENSG00000173517 ENSG00000100664 ENSG00000132842 ENSG00000105568 ENSG00000291420 ENSG00000181704 ENSG00000120063 ENSG00000007168 ENSG00000106105 ENSG00000138777 ENSG00000137076 ENSG00000111786 ENSG00000124209 ENSG00000134108 ENSG00000132341 ENSG00000138801 ENSG00000111481 PMC11849169__F5 Construction of a biosynthetic pathway for CK production in S ENSG00000157554 ENSG00000074800 ENSG00000197429 PMC4530213__F5 Functional connections brought by the active clusters between T2D and obesity ENSG00000171105 ENSG00000213341 ENSG00000187266 ENSG00000099942 ENSG00000105639 ENSG00000179295 ENSG00000110395 ENSG00000105397 ENSG00000122756 ENSG00000067606 ENSG00000177606 ENSG00000292357 ENSG00000146648 ENSG00000113494 PMC8385664__F2 microRNAs, the Link Between Dengue Virus and the Host Genome ENSG00000172936 PMC11876490__F4 Enrichment by Gene Ontology (GO) and pathway terms were visualized using the ClueGO/CluePedia plugin from Cytoscape ENSG00000140263 ENSG00000070961 ENSG00000124635 ENSG00000288217 ENSG00000112667 ENSG00000038002 ENSG00000205220 ENSG00000159720 ENSG00000100387 ENSG00000132646 ENSG00000138768 ENSG00000137267 ENSG00000169567 PMC7544989__F10 Ouabain effects in cultured human skeletal muscle cells ENSG00000163399 ENSG00000291971 ENSG00000168610 PMC4344548__F1 Sites of canonical Wnt signaling deregulation in PD ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000277641 PMC9598597__F3 Protective Effects of Natural Antioxidants on Inflammatory Bowel Disease: Thymol and Its Pharmacological Properties ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC12066262__F1 Pancreatic intestinal lung pathway in acute pancreatitis PMC7053872__F5 Potential pathway of NAFLD development ENSG00000187048 ENSG00000125538 ENSG00000167419 PMC5797541__F1 Representation of proteins and protein complexes involved in the “Autophagy – animal” KEGG pathway ENSG00000144848 ENSG00000087842 PMC8990928__F1 Genotype-Guided Prescription of Azathioprine Reduces the Incidence of Adverse Drug Reactions in TPMT Intermediate Metabolizers to a Similar Incidence as Normal Metabolizers ENSG00000137364 ENSG00000136159 ENSG00000158125 PMC2604897__F2 Putative biochemical pathways involving MGAT3 ENSG00000140262 ENSG00000132478 PMC9698579__F3 Can Natural Products Targeting EMT Serve as the Future Anticancer Therapeutics? ENSG00000100234 ENSG00000170558 PMC3109034__F6 Working model for the role of the miR-29 family in TGFB2–mediated signaling PMC6321710__F9 Pathway visualization ENSG00000171105 ENSG00000110395 ENSG00000150907 PMC5123939__F1 Two-signal model for NLRP3 inflammasome activation ENSG00000162711 ENSG00000185515 ENSG00000088888 ENSG00000167207 ENSG00000125538 ENSG00000036828 ENSG00000168040 ENSG00000173612 ENSG00000106100 ENSG00000184216 PMC5123939__F2 Activation for non-canonical and alternative NLRP3 inflammasomes ENSG00000162711 ENSG00000137275 ENSG00000172936 ENSG00000136869 ENSG00000168040 PMC9428607__F2 Dopamine Receptors: Is It Possible to Become a Therapeutic Target for Depression? ENSG00000276825 ENSG00000184845 ENSG00000169676 ENSG00000105723 ENSG00000149295 PMC3949576__F2 Effective double whammy targets DNA synthesis in leukemia ENSG00000124479 ENSG00000167900 PMC7457014__F5 Knockdown of DAP alters gene expression of the mTOR signaling pathway during proliferation of turkey satellite cells ENSG00000177169 ENSG00000163435 ENSG00000198793 ENSG00000163914 PMC1782267__F2 TGF–TAK1 pathway PMC1782267__F1 TGFB1–Smad pathway ENSG00000137834 PMC8317223__F2 Properties, Pharmacology, and Pharmacokinetics of Active Indole and Oxindole Alkaloids in Uncaria Hook ENSG00000165841 PMC7581990__F1 Metabolic reprogramming is involved in malignant transformation of prostatic cells ENSG00000131473 ENSG00000169710 ENSG00000102977 PMC5832558__F1 Urinary excretion of citric acid (TCA) cycle metabolites and the renal expression of genes that regulate these metabolites were significantly reduced among participants with versus without non-diabetic CKD ENSG00000143252 ENSG00000073578 ENSG00000100412 ENSG00000197444 ENSG00000117118 ENSG00000163541 ENSG00000105953 ENSG00000172340 ENSG00000101365 ENSG00000062485 PMC8645640__F7 Metformin Downregulates PD-L1 Expression in Esophageal Squamous Cell Carcinoma by Inhibiting IL-6 Signaling Pathway ENSG00000168610 PMC4089598__F2 Regulatory T cells and co-stimulatory pathways ENSG00000134982 ENSG00000163599 PMC7923240__F8 De Novo Transcriptome Assembly of Two Microsorum Fern Species Identifies Enzymes Required for Two Upstream Pathways of Phytoecdysteroids ENSG00000110921 ENSG00000116133 ENSG00000172893 ENSG00000197429 ENSG00000167508 PMC9117991__F5 Lactate and the Lactate Dehydrogenase in Inflammatory Diseases and Major Risk Factors in COVID-19 Patients ENSG00000026508 PMC5240418__F1 The notch signalling pathway in prostate cancer ENSG00000148400 PMC8762210__F11 High Ratio of the Plasma miR-96/miR-99b Correlated With Poor Prognosis in Patients With Metastatic Colorectal Cancer ENSG00000140992 ENSG00000198793 ENSG00000169047 ENSG00000263014 ENSG00000118515 ENSG00000164327 ENSG00000141564 ENSG00000114573 ENSG00000121879 ENSG00000143882 ENSG00000140443 PMC8762210__F10 High Ratio of the Plasma miR-96/miR-99b Correlated With Poor Prognosis in Patients With Metastatic Colorectal Cancer ENSG00000132906 ENSG00000172380 ENSG00000183486 ENSG00000105639 ENSG00000242616 ENSG00000197461 ENSG00000156475 ENSG00000078304 ENSG00000105664 ENSG00000117020 ENSG00000160867 ENSG00000134853 ENSG00000154188 ENSG00000102104 PMC6352191__F7 Proposed regulatory network involved in Keratinocytes of Type 2 Diabetes ENSG00000239732 ENSG00000187608 ENSG00000183486 ENSG00000157601 ENSG00000111331 ENSG00000010671 PMC5926825__F1 Reactive Oxygen Species in Metabolic and Inflammatory Signaling ENSG00000149311 ENSG00000167323 ENSG00000198793 PMC6352191__F6 Protein–protein interaction (PPI) network in cluster 1 from the MCODE sub-network analysis ENSG00000213928 ENSG00000110330 ENSG00000167207 ENSG00000187608 ENSG00000291971 ENSG00000183486 ENSG00000157601 ENSG00000205413 ENSG00000135899 ENSG00000132530 ENSG00000150991 ENSG00000088888 ENSG00000133106 ENSG00000188313 ENSG00000066044 ENSG00000100142 ENSG00000145782 ENSG00000142192 ENSG00000185885 ENSG00000105953 ENSG00000125347 ENSG00000184979 ENSG00000115415 ENSG00000137965 ENSG00000138642 ENSG00000059378 ENSG00000111331 ENSG00000146648 PMC7857696__F1 Natural and synthetic mucin-type O-glycosylation pathways ENSG00000070526 ENSG00000166278 PMC7338805__F7 Proteasome subunit PSMC3 variants cause neurosensory syndrome combining deafness and cataract due to proteotoxic stress ENSG00000178573 ENSG00000106459 PMC9138239__F1 Key Molecules of Fatty Acid Metabolism in Gastric Cancer ENSG00000131473 ENSG00000172216 ENSG00000198793 ENSG00000169710 ENSG00000168036 ENSG00000174059 ENSG00000124795 ENSG00000152430 ENSG00000026103 PMC11591473__F6 Oxidative stress induced senescence pathway ENSG00000162889 ENSG00000171855 ENSG00000141503 ENSG00000177606 ENSG00000065559 ENSG00000074266 ENSG00000132510 ENSG00000178691 ENSG00000114738 PMC7381543__F2 Molecular and metabolic regulation of effector and memory T cell differentiation ENSG00000139193 ENSG00000186810 ENSG00000138795 ENSG00000138378 ENSG00000139187 ENSG00000115415 ENSG00000134982 ENSG00000197272 ENSG00000089041 ENSG00000168610 PMC11095605__F2 Activation and inhibition of the Wnt/Beta-catenin signaling pathway ENSG00000120057 ENSG00000167874 ENSG00000168036 PMC5124731__F1 Production of aromatic compounds via shikimate pathway in microbes ENSG00000108849 ENSG00000128602 PMC11591473__F4 Detoxification of reactive oxygen species pathway ENSG00000173992 ENSG00000086991 ENSG00000100348 ENSG00000176153 PMC9166526__F5 Hypoxia-inducible factors: master regulators of hypoxic tumor immune escape ENSG00000167601 ENSG00000291971 ENSG00000272398 ENSG00000168036 PMC8165473__F2 Anti-inflammatory and Proangiogenic Properties of High-Density Lipoproteins: An Emerging Role in Diabetic Wound Healing ENSG00000108691 ENSG00000163739 ENSG00000162692 PMC9501315__F2 Cardio-Oncology: Mechanisms, Drug Combinations, and Reverse Cardio-Oncology ENSG00000110799 ENSG00000198793 ENSG00000171791 ENSG00000079999 PMC11015399__F1 Hippo signalling pathway and its impact on eye diseases ENSG00000186575 ENSG00000163914 PMC5994134__F4 Reconstruction of metabolic pathway of Woesearchaeota in the central carbon (a) and comparison of genes relating to the ferredoxin-dependent pathways between organisms from oxic and anoxic biotopes (b) ENSG00000122218 ENSG00000105402 ENSG00000158516 PMC10529747__F3 TGFB as A Master Regulator of Aging-Associated Tissue Fibrosis ENSG00000149311 ENSG00000086991 PMC6168472__F7 Proposed mechanistic model of KMT2D in prostate cancer ENSG00000140992 ENSG00000099985 ENSG00000128342 ENSG00000136826 PMC2854285__F2A mTOR and cancer: many loops in one pathway ENSG00000155792 PMC4578605__F3 Depletion of Pkh affects glycogen metabolism ENSG00000169299 ENSG00000013375 PMC12154116__F10 KEGG pathway maps enriched with downregulated differentially expressed genes (DEGs) in THP-1 cells following treatment with Biochanin A (100 μM) ENSG00000118007 ENSG00000108055 ENSG00000179091 ENSG00000167513 ENSG00000164190 ENSG00000277273 ENSG00000129933 ENSG00000140534 ENSG00000276876 ENSG00000093009 ENSG00000141446 ENSG00000137812 ENSG00000145604 ENSG00000172167 ENSG00000101972 ENSG00000132646 ENSG00000081377 ENSG00000123374 ENSG00000164754 ENSG00000071539 PMC2861828__F1 Signaling pathway that connects store-operated Ca2+ entry with NFAT-dependent gene transcription in T cells ENSG00000213658 ENSG00000293604 ENSG00000156026 ENSG00000113263 PMC8277837__F5 Network and co-expression analysis of airway smooth muscle cell transcriptome delineates potential gene signatures in asthma ENSG00000167553 ENSG00000123416 ENSG00000188229 ENSG00000136826 ENSG00000170365 ENSG00000143379 ENSG00000197714 ENSG00000283060 ENSG00000118058 ENSG00000171105 ENSG00000151012 ENSG00000103150 ENSG00000176014 ENSG00000167552 ENSG00000197054 ENSG00000083812 ENSG00000076555 ENSG00000178338 ENSG00000251369 ENSG00000197808 ENSG00000075407 ENSG00000198182 ENSG00000198551 ENSG00000167772 ENSG00000196357 ENSG00000196437 ENSG00000171649 ENSG00000187554 ENSG00000180855 ENSG00000142556 PMC11876390__F1 Metabolic pathways of polyamines ENSG00000081181 ENSG00000095059 ENSG00000148832 ENSG00000288145 ENSG00000129932 ENSG00000036473 ENSG00000116649 ENSG00000102172 PMC2984459__F1 Schematic overview of Toll-like receptor (TLR)4 signaling pathway ENSG00000170458 ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC6417856__F10 The main findings are illustrated (A) ENSG00000196218 ENSG00000067191 ENSG00000132639 PMC6481626__F1 Pathways that influence uracil accumulation in DNA ENSG00000167900 PMC4231421__F7 LPA-dependent platelet-induced tumor cell metastasis ENSG00000138798 ENSG00000173599 ENSG00000198670 PMC6501144__F2 Angiogenesis signaling pathways induced by oxidative stress ENSG00000149311 ENSG00000172936 ENSG00000175104 ENSG00000164342 PMC3016978__F6 Model for a meiotic gene regulatory cascade initiated by inactivation of a pathway that promotes turnover of meiotic transcripts produced in vegetatively growing cells ENSG00000269964 ENSG00000285007 PMC9690211__F6 Transcriptome Analysis of Chinese Cabbage Provides Insights into the Basis of Understanding the Lignin Affected by Low Temperature ENSG00000084774 PMC5762868__F1 Schematic diagram of the metabolic cycle of THF and the C1 metabolic pathway ENSG00000065911 ENSG00000100714 ENSG00000145020 ENSG00000120254 PMC7163125__F10 LXA4, a potential therapeutic agent against KSHV ENSG00000198793 ENSG00000118515 ENSG00000106546 PMC7226428__F1 Growth hormone (GH) on the vascular endothelium ENSG00000169291 ENSG00000112964 ENSG00000291971 PMC3414427__F3 Schematic model showing the existence of distinct secretory pathways in pheochromocytoma ENSG00000163618 ENSG00000123454 ENSG00000141744 ENSG00000132639 PMC4613136__F2 CD8 Memory Cells Develop Unique DNA Repair Mechanisms Favoring Productive Division ENSG00000012061 ENSG00000143799 ENSG00000172613 ENSG00000291803 ENSG00000067369 ENSG00000064933 ENSG00000012048 ENSG00000175054 ENSG00000105486 ENSG00000113456 ENSG00000276618 ENSG00000079246 ENSG00000113318 ENSG00000182185 ENSG00000108384 ENSG00000170430 ENSG00000123415 ENSG00000139372 ENSG00000051180 ENSG00000188486 ENSG00000185379 ENSG00000139618 ENSG00000149311 ENSG00000151164 ENSG00000095002 ENSG00000136936 ENSG00000122512 ENSG00000138385 PMC4613136__F1 CD8 Memory Cells Develop Unique DNA Repair Mechanisms Favoring Productive Division ENSG00000012061 ENSG00000143799 ENSG00000172613 ENSG00000291803 ENSG00000067369 ENSG00000064933 ENSG00000012048 ENSG00000175054 ENSG00000105486 ENSG00000113456 ENSG00000276618 ENSG00000079246 ENSG00000113318 ENSG00000108384 ENSG00000170430 ENSG00000123415 ENSG00000139372 ENSG00000051180 ENSG00000253729 ENSG00000188486 ENSG00000185379 ENSG00000139618 ENSG00000149311 ENSG00000151164 ENSG00000095002 ENSG00000136936 ENSG00000122512 ENSG00000138385 PMC3131053__F1 Differential involvement of IKKB/NFKB signaling in neurons of the hypothalamic arcuate nucleus in the pathogenesis of obesity and hypertension ENSG00000115138 PMC4594510__F4 Schematic diagram for the signaling pathway involved in dexamethasone-induced TRPC4 channel activity ENSG00000133107 ENSG00000253506 ENSG00000108551 PMC8221613__F1 General schematic of astrocyte reprogramming using TFs and miRNAs ENSG00000139352 PMC7641965__F3 Integrating immunotherapy and targeted therapy in cancer treatment: mechanistic insights and clinical implications ENSG00000108702 ENSG00000169245 ENSG00000136997 ENSG00000108688 ENSG00000163734 ENSG00000168036 ENSG00000168610 ENSG00000146648 ENSG00000277943 PMC7641965__F1 Integrating immunotherapy and targeted therapy in cancer treatment: mechanistic insights and clinical implications ENSG00000089692 ENSG00000134982 ENSG00000118520 PMC5888911__F7 Schematic representation of the influence of high NT on FA anabolism and catabolism biosynthetic pathways ENSG00000173599 ENSG00000198670 PMC8740421__F7 Argonaute-2 protects the neurovascular unit from damage caused by systemic inflammation ENSG00000136869 ENSG00000123908 PMC3744802__F5 Model of regulation of the length of D-loop extension by PCNA and choice of polymerase ENSG00000132646 ENSG00000130997 ENSG00000122008 PMC11048329__F3 Schematic presentation of current evidence on Cx32 association with signaling pathways regulating proliferative and cell death processes ENSG00000137275 ENSG00000291971 ENSG00000198793 ENSG00000168404 ENSG00000146648 ENSG00000285379 PMC11048329__F2 Schematic presentation of current evidence on Cx32 association with EMT and the HCC chemotherapeutic resistance with oxaliplatin or doxorubicin ENSG00000168036 PMC3594782__F1 Serotonergic transcriptional networks and potential importance to mental health ENSG00000139287 ENSG00000116096 PMC7609422__F1 Core proteins involved in the autophagy pathway and its regulation in zebrafish, knockout (KO) zebrafish lines highlighted in red, and boxes show commonly used drugs which can activate (green) or inhibit (red) autophagy activity ENSG00000177169 ENSG00000110497 ENSG00000123395 ENSG00000123240 ENSG00000169682 ENSG00000198793 ENSG00000144848 ENSG00000005893 ENSG00000145782 ENSG00000057663 ENSG00000136048 PMC2196031__F8 Schematic presentation of the proposed sites of inhibition of the ceramide pathway by CrmA and Bcl-2 ENSG00000168040 ENSG00000026103 PMC6607964__F6 Snapshot of trastuzumab resistance pathway PMC3030666__F2 Impact of Aging on Dendritic Cell Functions in humans ENSG00000172936 PMC4682110__F5 Frequent alterations in cytoskeleton remodelling genes in primary and metastatic lung adenocarcinomas ENSG00000005339 ENSG00000157764 ENSG00000070831 ENSG00000168702 ENSG00000175793 ENSG00000134982 ENSG00000291971 ENSG00000198793 ENSG00000117139 ENSG00000181555 ENSG00000169032 ENSG00000131941 ENSG00000183765 ENSG00000038382 ENSG00000291754 ENSG00000169750 ENSG00000135446 ENSG00000136997 ENSG00000186765 ENSG00000105810 ENSG00000146648 ENSG00000127616 ENSG00000175305 PMC11528492__F5 Bioinformatic reconstruction of the L ENSG00000158104 ENSG00000171759 ENSG00000062485 PMC7901941__F1 Characterizing oligodendrocytes throughout the lineage ENSG00000184221 ENSG00000197971 ENSG00000134853 ENSG00000100146 ENSG00000237834 PMC3715049__F1 Proteomic strategies for studying the mechanism of miRNA processing and miRNA-mediated translation repression ENSG00000260428 ENSG00000116649 ENSG00000113360 PMC5937267__F1 Finally, expression of T-cell co-stimulatory and co-inhibitory receptors can be modulated by hypoxia as well ENSG00000151882 ENSG00000049768 PMC4026680__F1 Early life stress can influence development of the HPA axis, as well as regulation of satiety-related hormones, leptin, insulin, and ghrelin to alter feeding behavior long-term ENSG00000198576 PMC4391824__F3 Expression of the known genes involved in polo signaling in PAH HPASMC ENSG00000198901 ENSG00000065613 ENSG00000108055 ENSG00000134982 ENSG00000177084 PMC3807757__F1 MyD-88 dependent TLR signaling pathway: MyD-88 (*) associates with the cytoplasmic domain of TLR, recruiting IRAK1 and IRAK4 to activate TRAF6 ENSG00000174125 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC11379068__F8 The interaction between the PERK/ATF4 branch of endoplasmic reticulum stress response and mitochondrial one-carbon metabolism after ICH ENSG00000065911 ENSG00000128272 PMC11549785__F1 LncRNAs modulate MR of solid tumor cells by targeting glucose metabolism ENSG00000074800 ENSG00000198793 ENSG00000073792 ENSG00000145782 ENSG00000057663 PMC4768675__F9 RNA-Seq of the Caribbean reef-building coral Orbicella faveolata (Scleractinia-Merulinidae) under bleaching and disease stress expands models of coral innate immunity ENSG00000088888 ENSG00000132478 ENSG00000083799 ENSG00000145782 ENSG00000057663 PMC10537991__F4 Quantitative Differences in Rumen Epithelium Proteins in Lambs Fed Wheat, Perennial Wheat, or Perennial Wheat plus Lucerne ENSG00000116353 ENSG00000145439 ENSG00000206527 ENSG00000255154 ENSG00000176715 ENSG00000122971 ENSG00000100294 ENSG00000101365 PMC6305318__F2 Summary of the interactions between SIRT1 and the canonical Wnt pathway ENSG00000134982 ENSG00000168036 ENSG00000189403 ENSG00000096717 PMC4768675__F6 RNA-Seq of the Caribbean reef-building coral Orbicella faveolata (Scleractinia-Merulinidae) under bleaching and disease stress expands models of coral innate immunity ENSG00000196839 ENSG00000124232 PMC3714282__F1 Pharmacometabolomics of Response to Sertraline and to Placebo in Major Depressive Disorder – Possible Role for Methoxyindole Pathway PMC11549785__F4 LncRNAs orchestrate MR in solid tumor cells by influencing interactions between tumor and non-tumor cells in TME ENSG00000145824 PMC7074507__F1 TCR/CD3 complex and CD28 downstream signaling pathways leading to activation of transcription of genes for cytokines, chemokines, cell division, activation of effector function, and survival ENSG00000070831 ENSG00000163599 ENSG00000198793 PMC4768675__F7 RNA-Seq of the Caribbean reef-building coral Orbicella faveolata (Scleractinia-Merulinidae) under bleaching and disease stress expands models of coral innate immunity ENSG00000162711 ENSG00000087077 PMC3522553__F1 Components of the Hedgehog (Hh) Signaling Pathway and molecular sites targeted by Hh pathway inhibitors ENSG00000164690 ENSG00000128602 PMC11549785__F2 LncRNAs modulate MR of solid tumor cells by influencing lipid metabolism ENSG00000151726 ENSG00000135218 ENSG00000181163 ENSG00000092199 PMC9010455__F2 Upstream Regulator Analysis, based on “omics” integration using the Ingenuity Pathway Analysis software ENSG00000167601 ENSG00000087245 ENSG00000165119 ENSG00000187608 ENSG00000181163 ENSG00000100906 ENSG00000198793 ENSG00000173039 ENSG00000110651 ENSG00000166278 ENSG00000168610 ENSG00000143320 ENSG00000177606 ENSG00000026508 ENSG00000146648 ENSG00000127616 PMC7841890__F4 Activation of the antioxidant signalling pathway by natural remedies against polyQ-induced SCA PMC8235637__F3 Molecular and Functional Analysis of Sunitinib-Resistance Induction in Human Renal Cell Carcinoma Cells ENSG00000122025 ENSG00000157404 ENSG00000135218 ENSG00000198793 ENSG00000061273 ENSG00000005893 ENSG00000168036 ENSG00000064547 ENSG00000171517 ENSG00000147145 PMC3132554__F2 Small-molecule inhibitors of the PI3K signaling network ENSG00000132906 ENSG00000002330 PMC7484123__F1 Metabolism of hydrogen sulfide ENSG00000137767 ENSG00000139531 ENSG00000116761 PMC5546429__F8 Chronic diabetic states worsen Alzheimer neuropathology and cognitive deficits accompanying disruption of calcium signaling in leptin-deficient APP/PS1 mice ENSG00000198793 PMC11084413__F5 KEGG pathway analysis of carnosic acid downregulated proteins associated with glycolysis/gluconeogenesis ENSG00000159399 PMC8948419__F5 Molecular physiology regulating cold tolerance and acclimation of Caenorhabditis elegans PMC9294245__F4 Drug Resistance Mechanisms of Acute Myeloid Leukemia Stem Cells ENSG00000171791 PMC9294245__F2 Drug Resistance Mechanisms of Acute Myeloid Leukemia Stem Cells ENSG00000128602 ENSG00000146374 PMC6843238__F2 ALDH1A1-retinoic acid-HIF-1Alpha-VEGF pathway is activated in breast cancer MCF-7 cells (A) ENSG00000107562 ENSG00000291971 ENSG00000136997 ENSG00000121966 PMC4889241__F4 p27 in cell-cycle regulation ENSG00000163914 ENSG00000205250 ENSG00000166508 PMC12246546__F8 Research progress of ECT2 and RhoA-related signaling pathways in gynecological tumors ENSG00000179913 PMC5691642__F2 Suppression of type I IFN production by Flaviviridae viruses ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000276561 PMC12246546__F5 Research progress of ECT2 and RhoA-related signaling pathways in gynecological tumors ENSG00000149311 ENSG00000114346 ENSG00000143878 PMC6784043__F1 Novel insights into the dectin-1 signaling pathway ENSG00000187796 ENSG00000197943 ENSG00000116525 ENSG00000007171 PMC2896660__F2 Placing datasets into a functional context using pathway analysis ENSG00000142192 ENSG00000138326 ENSG00000198125 PMC5822656__F1 MiRNA biogenesis, function in cytoplasm and nucleus-cytoplasm transport ENSG00000172795 ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC6089847__F2 Pathways of T-cell inactivation and mechanisms of monoclonal antibodies ENSG00000135077 ENSG00000181847 ENSG00000163599 PMC7660678__F1 Pathway for the endogenous synthesis of arginine ENSG00000081181 ENSG00000118520 PMC5541427__F5 Effect of selecting different subsets of CpG sites in the “TNF signaling pathway” ENSG00000078747 ENSG00000137392 ENSG00000177606 ENSG00000038002 PMC6784043__F2 Crosstalk between different PRRs in antifungal immunity ENSG00000162711 ENSG00000187796 ENSG00000125538 ENSG00000132478 ENSG00000172936 ENSG00000125347 PMC5541427__F1 Snapshot of PiiL in group-wise view mode, showing the “cell cycle” pathway ENSG00000149311 ENSG00000198176 ENSG00000132646 ENSG00000136997 ENSG00000166851 ENSG00000167182 ENSG00000117399 PMC6991658__F9 Mechanism diagram ENSG00000149311 ENSG00000170558 ENSG00000123374 PMC5921923__F1 Using gene expression data to direct breast cancer therapy: Evidence from a pre-clinical trial ENSG00000291971 ENSG00000136997 ENSG00000168610 ENSG00000146648 PMC5541427__F2 “cytokine-cytokine receptor interaction” subsection of the “pathways in cancer” pathway, with (a) DNA methylation data, and (b) gene expression data ENSG00000019991 ENSG00000157404 ENSG00000101109 ENSG00000138798 ENSG00000169032 ENSG00000168610 ENSG00000068028 ENSG00000122025 ENSG00000017797 ENSG00000049130 ENSG00000163235 ENSG00000135446 ENSG00000148204 ENSG00000177606 ENSG00000136997 ENSG00000006451 ENSG00000134853 ENSG00000169429 ENSG00000124181 ENSG00000077782 ENSG00000146648 PMC7781009__F1 MET oncogenic activation ENSG00000047410 ENSG00000019991 ENSG00000110395 ENSG00000010270 PMC9047906__F5 Serglycin Is Involved in TGFB Induced Epithelial-Mesenchymal Transition and Is Highly Expressed by Immune Cells in Breast Cancer Tissue ENSG00000105329 ENSG00000026508 ENSG00000122862 PMC3887911__F4 CRAC channel regulation by multiple Ca2+-sensing molecules in the ER and cytoplasm ENSG00000130038 ENSG00000167323 ENSG00000293604 PMC3887911__F3 Interacting partners and posttranslational modification of Orai1 and STIM1 ENSG00000130038 ENSG00000167323 ENSG00000293604 PMC3887911__F2 Activation mechanism of Orai1 and STIM1 ENSG00000291603 ENSG00000213658 ENSG00000070831 ENSG00000167323 ENSG00000293604 ENSG00000141968 PMC9207250__F2 Vitamin D: A Potential Star for Treating Chronic Pancreatitis ENSG00000111012 ENSG00000152266 ENSG00000019186 ENSG00000186104 ENSG00000106546 ENSG00000135929 PMC6390244__F4 Target-pathway network analyses results ENSG00000151834 ENSG00000133019 ENSG00000150594 ENSG00000170214 ENSG00000103546 ENSG00000198125 ENSG00000120251 ENSG00000171033 ENSG00000276996 ENSG00000043591 ENSG00000073756 ENSG00000254550 PMC8866335__F2 Small, Dense Low-Density Lipoprotein-Cholesterol and Atherosclerosis: Relationship and Therapeutic Strategies ENSG00000130164 ENSG00000144935 ENSG00000163914 ENSG00000180432 ENSG00000162772 ENSG00000138741 PMC2645860__F2 Pathogenetic mechanisms of CCAAT enhancer binding protein alpha (C/EBPA) dysfunction ENSG00000071575 ENSG00000148400 ENSG00000186716 ENSG00000067955 PMC5015973__F8 Sexual Fate Change of XX Germ Cells Caused by the Deletion of SMAD4 and STRA8 Independent of Somatic Sex Reprogramming ENSG00000146857 ENSG00000156574 ENSG00000188425 PMC1779900__F6 Some signaling pathways that could mediate long-term changes in cellular plasticity as a function of sexual experience ENSG00000169291 ENSG00000198576 PMC8620571__F1 An Atypical Case of Congenital Erythropoietic Porphyria ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000158578 ENSG00000256269 ENSG00000188690 PMC4761092__F10 Scheme of the role of (+)‐naltrexone and (+)‐naloxone in TLR4 signalling ENSG00000172936 ENSG00000136869 PMC4864395__F5 Menadione Suppresses Benzo(A)pyrene-Induced Activation of Cytochromes P450 1A: Insights into a Possible Molecular Mechanism ENSG00000140465 ENSG00000106546 PMC12069246__F3 P38 MAPK signaling pathway is regulated by ubiquitination in MASLD ENSG00000184979 ENSG00000159069 ENSG00000112343 ENSG00000118503 ENSG00000082512 ENSG00000157625 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000221926 PMC3663533__F8 The regulation of TLR signaling by Lgr4 ENSG00000281324 ENSG00000162337 ENSG00000170458 ENSG00000168036 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC8998228__F1 Metazoans and Intrinsic Apoptosis: An Evolutionary Analysis of the Bcl-2 Family ENSG00000100290 ENSG00000002330 ENSG00000135116 ENSG00000104081 PMC10520882__F7 Biased M3 mAChR ligand PD 102807 mediates qualitatively distinct signaling to regulate airway smooth muscle phenotype ENSG00000004660 ENSG00000198793 ENSG00000110931 PMC7343490__F2 Network analysis including the 125 differentially expressed proteins at 24 h after SARS-CoV-2 in Caco-2 cells ENSG00000049323 ENSG00000118007 ENSG00000277909 ENSG00000058085 ENSG00000178999 ENSG00000122966 ENSG00000197746 ENSG00000153201 ENSG00000087586 ENSG00000081051 ENSG00000164934 ENSG00000126218 ENSG00000245848 ENSG00000291527 ENSG00000069869 ENSG00000186847 ENSG00000100142 ENSG00000185591 ENSG00000158874 ENSG00000123562 PMC3632385__F2 Schematic overview of estradiol-mediated genomic signaling pathway via ERA/B and rapid nongenomic signaling pathways via GPER, Gq-mER, and membrane subpopulation mERA/B ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC4522276__F1 Molecular Insight into Dengue Virus Pathogenesis and its Implications for Disease Control ENSG00000164430 ENSG00000115415 PMC7503882__F2 Molecular pathogenic signaling pathways in ACM ENSG00000186575 ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC5037500__F2 A glutamatergic synapse and the molecular circadian clockwork ENSG00000196531 ENSG00000131095 PMC5346417__F5 Diagram showing the hypothetical model for regulation of NCC phosphorylation in the DCT cell, and hence the level of transcellular NaCl flux ENSG00000126562 ENSG00000177807 ENSG00000080166 PMC4350352__F6 TAp73 promotes anabolism ENSG00000078900 ENSG00000220205 ENSG00000104888 PMC5548957__F2 Rotavirus interactions with the host innate system: viral entry into cells and viral double strand RNA (dsRNA) induce the generation of pathogen-associated molecular pathways (PAMPs) ENSG00000183735 ENSG00000213928 ENSG00000107201 ENSG00000276561 ENSG00000164342 PMC7911620__F1 TLR-activating adjuvants and the induced signalling pathway ENSG00000174125 ENSG00000108691 ENSG00000239732 ENSG00000117400 ENSG00000187554 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC6409969__F7 Cell Cycle Arrest and Cytotoxic Effects of SAHA and RG7388 Mediated through p21WAF1/CIP1 and p27KIP1 in Cancer Cells ENSG00000178999 PMC11808623__F5 Mechanism of CSEAE regulated angiogenesis in atherosclerosis by modulating the miR-126/VEGF signalling pathway (Created with BioRender ENSG00000167508 PMC2886300__F2 Role of ROS in TNFA induced endothelial dysfunction ENSG00000157933 ENSG00000076604 PMC4462130__F6 a, Gene interaction map of Reactome pathway analysis that discovers alteration of FGFR signaling as the most altered pathway ENSG00000118972 ENSG00000152495 ENSG00000102606 ENSG00000105401 ENSG00000169047 ENSG00000164327 ENSG00000121879 ENSG00000089159 ENSG00000081913 ENSG00000160867 ENSG00000174233 ENSG00000150907 ENSG00000134853 ENSG00000077782 ENSG00000171608 ENSG00000105723 ENSG00000178568 PMC3998024__F2 Top-ranked gene network ENSG00000139193 ENSG00000135148 ENSG00000162897 ENSG00000145777 ENSG00000277943 ENSG00000057663 ENSG00000226275 ENSG00000163625 ENSG00000165458 ENSG00000186716 ENSG00000168374 ENSG00000233816 ENSG00000169397 ENSG00000131323 PMC5799271__F2 TLR4 signaling pathways ENSG00000183735 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC10938783__F7 Multifaceted mechanism of KTC1101 in anti-tumor therapy and immunomodulation ENSG00000169245 ENSG00000111537 ENSG00000198793 PMC2874340__F1 Folate cycle, methionine cycle, and transsulfuration pathway PMC8507309__F5 RNA-Seq reveals different responses to drought in Neotropical trees from savannas and seasonally dry forests ENSG00000152348 ENSG00000123395 ENSG00000221818 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC5729411__F7 Summary of the main findings ENSG00000134982 ENSG00000168036 ENSG00000074266 ENSG00000100985 ENSG00000164342 PMC8228919__F1 Toll-Like Receptor Signaling in the Establishment and Function of the Immune System ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000110057 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC6891142__F4 The suppressive effects of Crabp1 in adipogenesis and adipocyte hypertrophy ENSG00000245848 ENSG00000172216 ENSG00000169047 ENSG00000168036 ENSG00000140443 PMC10857877__F6 RND3 induction and interaction with TLR4 and IFNG receptor signaling in activated proinflammatory macrophages ENSG00000169245 ENSG00000148400 PMC7487489__F7 MAPK signaling pathway ENSG00000087095 ENSG00000170458 ENSG00000102871 ENSG00000130159 ENSG00000127191 ENSG00000026103 PMC4768065__F7 Proposed model of the involvement of Spry2 and Spry2 siRNA in TLR, IFNG receptor, and growth factor signaling pathways for suppression of M1 polarization and enhancement of M2 polarization in macrophages ENSG00000136158 ENSG00000111537 ENSG00000138798 ENSG00000172936 ENSG00000118520 PMC7226927__F5 Action of Hedgehog signaling pathway ENSG00000106571 ENSG00000128602 PMC7985092__F1 Schematic diagram of the insulin-like growth factor (IGF) signal transduction and main downstream effects ENSG00000169291 ENSG00000171105 ENSG00000002330 ENSG00000197081 ENSG00000169047 ENSG00000155792 ENSG00000140443 PMC8904960__F1 Non-Canonical Roles of Apoptotic Caspases in the Nervous System ENSG00000120868 ENSG00000026103 PMC4666504__F7 Neuregulin-activated ERBB4 induces the SREBP-2 cholesterol biosynthetic pathway and increases low-density lipoprotein uptake ENSG00000138798 ENSG00000146648 ENSG00000178568 PMC6341984__F1 Tuberculosis and impaired IL-23-dependent IFNG immunity in humans homozygous for a common TYK2 missense variant ENSG00000162594 ENSG00000096996 ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000168610 ENSG00000142166 PMC7337897__F6 MDM2 regulates E2F1 synthesis during EBNA1 mRNA-induced translation stress ENSG00000135446 ENSG00000123374 PMC9565759__F4 Possible Synergies of Nanomaterial-Assisted Tissue Regeneration in Plasma Medicine: Mechanisms and Safety Concerns ENSG00000198901 ENSG00000173992 ENSG00000168610 PMC7985092__F2 Several proteins in the IGF signaling pathway such as IGF1, IGF2, IGF-1R, and IGFBPs are regulated by miRNAs ENSG00000163435 ENSG00000171105 ENSG00000002330 ENSG00000198793 ENSG00000169047 ENSG00000146678 ENSG00000133124 PMC8275668__F6 Application across species of a one health approach to liquid sample handling for respiratory based -omics analysis ENSG00000162368 ENSG00000291363 ENSG00000173369 ENSG00000113905 ENSG00000170558 ENSG00000168374 ENSG00000133661 ENSG00000134287 ENSG00000273686 ENSG00000159189 ENSG00000079557 PMC4365929__F3 Ultraviolet B (UVB)-induced cell cycle signaling and the relationship between p53 and phospho-Chk1 (Ser317) ENSG00000175054 ENSG00000134057 PMC3092200__F9 Hypothetic scheme of cell death induction pathway triggered roscovitine and CR8 in human neuroblastoma (NB) cells ENSG00000136807 ENSG00000277273 ENSG00000134480 PMC4881378__F1 Components of the TLR signaling network frequently mutated in lymphoid neoplasms ENSG00000187554 ENSG00000136997 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000083799 ENSG00000150455 ENSG00000175104 PMC6696953__F2 ASD gene networks constructed with PASCAL associated genes and its FunCoup interactors ENSG00000196839 ENSG00000143839 ENSG00000183684 ENSG00000143933 ENSG00000169813 ENSG00000080709 ENSG00000163938 ENSG00000188612 ENSG00000129351 ENSG00000145220 PMC8592893__F4 Adroitness of Andrographolide as a Natural Weapon Against Colorectal Cancer ENSG00000198793 ENSG00000172936 ENSG00000150455 PMC10815665__F3 Proposed conceptual framework for the involvement of CXCR signaling in modulating Th1/Th17-driven pathologies ENSG00000163464 ENSG00000111537 ENSG00000121966 PMC3871617__F5 NHE Isoform Switching and KChIP2 Upregulation in Aging Porcine Atria ENSG00000182533 ENSG00000186716 ENSG00000148175 ENSG00000171388 PMC10815665__F2 CXCR signaling pathway ENSG00000169248 ENSG00000169245 ENSG00000107562 ENSG00000081041 ENSG00000161921 ENSG00000163739 ENSG00000138755 ENSG00000169429 ENSG00000124875 ENSG00000105639 PMC6962170__F4 Integrated metabolic, proteomic and transcriptomic functional analysis ENSG00000123416 ENSG00000088826 ENSG00000101180 ENSG00000126457 ENSG00000099810 ENSG00000146282 ENSG00000168610 ENSG00000128965 PMC12107871__F5 Proposal of the main molecular signaling pathways by which celecoxib exerts its anti-inflammatory action as a promising strategy in breast cancer therapy PMC5336563__F2 Regulatory networks of selected lncRNAs involved in the development of HBx-HCC ENSG00000123454 ENSG00000168036 ENSG00000123374 ENSG00000105810 PMC4346366__F1 Consequences of tissue trauma on heme catabolism, reactive oxygen species, and polyunsaturated fatty acid metabolism.Notes: Top panel: following tissue trauma, release of free heme can serve as a signal for proinflammatory events ENSG00000182511 ENSG00000148344 ENSG00000124212 ENSG00000073756 PMC11758948__F9 Cell division regulation by the EphA2–Ephexin4–RhoG signaling pathway ENSG00000142627 PMC7141213__F2 Examples of mechanisms involved in the cellular response to low doses of phytochemicals–on the basis of findings presented in the current review ENSG00000096717 ENSG00000079999 PMC12107871__F3 Schematic description of the signaling process demonstrating the intricate cross-talk between NFKB and STAT3 in inflammation-induced cancer ENSG00000087245 ENSG00000171791 ENSG00000100985 ENSG00000168610 PMC12107871__F2 Graphical depiction of mechanisms responsible for inflammatory response mediating the onset of cancer via STAT3 signaling pathway ENSG00000089685 ENSG00000163235 ENSG00000168610 ENSG00000146648 ENSG00000121966 PMC12107871__F1 Inflammatory signaling mechanisms underlying cancer development mediated by the NF-kB signaling pathway ENSG00000104856 ENSG00000108691 ENSG00000138798 ENSG00000186716 ENSG00000169429 ENSG00000111321 ENSG00000171791 ENSG00000146648 ENSG00000121966 PMC7408754__F2 Gas6/Axl signaling promotes the immunosuppressive tumor microenvironment ENSG00000108691 ENSG00000277943 PMC8391332__F1 Microbiota-Gut-Brain Communication in the SARS-CoV-2 Infection ENSG00000169245 ENSG00000130234 ENSG00000198793 ENSG00000132693 PMC4324046__F2 Metabolic reprogramming in rheumatoid arthritis T cells ENSG00000169710 PMC4295378__F1 WNT signaling network ENSG00000087095 ENSG00000134982 ENSG00000168036 ENSG00000132693 PMC3599859__F1 CySBGN overview ENSG00000105664 PMC4000313__F2 Death receptor signaling and programmed necrosis ENSG00000102871 ENSG00000168040 PMC2991541__F3 Redox-control of Matrix Metalloproteinase-1: A critical link between free radicals, matrix remodeling and degenerative disease ENSG00000132478 PMC8891514__F1 Pattern-Recognition Receptor Signaling by HBX During Hepatitis B Virus Infection ENSG00000162711 ENSG00000163568 ENSG00000091106 ENSG00000130159 ENSG00000127191 ENSG00000276561 ENSG00000135899 ENSG00000150782 ENSG00000183735 ENSG00000088888 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC9481235__F1 AIM2 Gene and AIM2 Inflammasome in the Pathogenesis and Treatment of Psoriasis ENSG00000239732 ENSG00000163568 ENSG00000087586 ENSG00000255501 PMC7037245__F2 IL-2R signaling and modulation of T cell activity ENSG00000033327 ENSG00000173757 ENSG00000049768 ENSG00000105639 ENSG00000160691 PMC2581785__F1 Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum ENSG00000149485 ENSG00000173599 ENSG00000084774 PMC11880738__F5 Dual role of copper in melanoma ENSG00000177169 ENSG00000115318 ENSG00000157764 ENSG00000173992 ENSG00000083290 ENSG00000196154 PMC2894618__F2 Lineage relationships of cells originating in the otocyst ENSG00000135547 ENSG00000106571 ENSG00000078579 ENSG00000117707 ENSG00000164690 ENSG00000077782 ENSG00000172238 PMC7936661__F3 Short loop commonality and a landscape of short loop commonality among proteins with mutations in the AML PPIN ENSG00000122025 ENSG00000008710 ENSG00000157404 ENSG00000171105 ENSG00000110395 ENSG00000072694 ENSG00000117400 ENSG00000164078 ENSG00000186716 ENSG00000115904 ENSG00000160691 PMC8262770__F1 Metabolic Control of Smoldering Neuroinflammation ENSG00000198793 ENSG00000183160 ENSG00000159399 PMC3631012__F1 Mi-2/NuRD complex making inroads into DNA-damage response pathway ENSG00000188486 ENSG00000175054 ENSG00000132646 ENSG00000196591 ENSG00000128908 PMC8794704__F2 Inflammasome and Its Therapeutic Targeting in Rheumatoid Arthritis ENSG00000154370 ENSG00000163568 ENSG00000125538 ENSG00000091106 PMC9582432__F2 Microglial autophagy in cerebrovascular diseases ENSG00000177169 ENSG00000198793 PMC8363009__F6 Chemical-protein and protein-protein interaction network of cordycepin and unique proteins from DM+COR and shared protein from N+COR and DM+COR in livers on the hepatic metabolism pathway, analyzed by STITCH v 5.0 ENSG00000181929 ENSG00000106617 ENSG00000100412 ENSG00000162409 ENSG00000150907 ENSG00000198793 ENSG00000105953 ENSG00000132356 ENSG00000146701 ENSG00000111725 PMC6441168__F3 Functional network of cancer derived EVs in GC microenvironment ENSG00000178860 ENSG00000189403 ENSG00000136869 PMC9352673__F5 Exosomes rewire the cartilage microenvironment in osteoarthritis: from intercellular communication to therapeutic strategies ENSG00000177575 ENSG00000135218 ENSG00000125398 ENSG00000125538 ENSG00000118520 ENSG00000069956 ENSG00000168610 PMC8447721__F1 Effective function of circular RNA in colorectal cancer ENSG00000078747 ENSG00000164305 PMC11274312__F6 PPI network of the DEGs in immune-related pathways ENSG00000139193 ENSG00000186810 ENSG00000138378 ENSG00000213658 ENSG00000198851 ENSG00000163599 ENSG00000163736 ENSG00000113263 ENSG00000180644 ENSG00000073861 ENSG00000188389 PMC5348722__F2 Translating genomic profiling to gastrointestinal cancer treatment ENSG00000149311 ENSG00000175054 ENSG00000157764 ENSG00000134982 ENSG00000198793 ENSG00000136997 ENSG00000168036 ENSG00000146648 ENSG00000109670 PMC7892431__F3 Dysregulation of nucleic acid-induced signaling during HCC development ENSG00000169245 ENSG00000164430 ENSG00000115415 ENSG00000163568 ENSG00000138798 ENSG00000164342 PMC7892431__F2 Viral manipulation of DNA-sensing and directly antiviral signaling pathways ENSG00000162711 ENSG00000163568 ENSG00000163565 ENSG00000160710 ENSG00000169871 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000144895 ENSG00000125538 ENSG00000172936 ENSG00000135828 ENSG00000121060 PMC5348722__F1 Translating genomic profiling to gastrointestinal cancer treatment ENSG00000198793 ENSG00000112715 ENSG00000146648 PMC4295378__F3 The WNT signaling network on cancer cell metabolism ENSG00000134982 ENSG00000168036 PMC7892431__F1 RNA sensing and viral manipulation of TLR and RLR signaling pathways ENSG00000162711 ENSG00000183735 ENSG00000088888 ENSG00000172936 ENSG00000064012 ENSG00000276561 PMC5951828__F6 Potential role for AstC-R2 in nociceptor-bacterial-immune interactions in Drosophila ENSG00000104321 PMC5069610__F2 NMI influences cancer initiation ENSG00000149311 ENSG00000123609 ENSG00000136997 ENSG00000136048 PMC11575122__F9 CARMN mechanism involving transcriptional and post-transcriptional regulation ENSG00000065978 ENSG00000137203 ENSG00000185591 ENSG00000079999 PMC4504941__F1 Molecular mechanisms of cardioprotection provoked by netrin-1 and netrin-1-derived small peptides ENSG00000181788 ENSG00000196470 PMC5069610__F3 NMI inhibits cancer progression ENSG00000071564 ENSG00000154342 ENSG00000169554 ENSG00000138795 ENSG00000123609 ENSG00000168036 ENSG00000196628 PMC6606950__F4 Herbal medicines promote the activation of the HIF-1 pathway through different targets in ischemic stroke ENSG00000198793 ENSG00000168610 PMC6606950__F3 Chinese herbal medicines inhibit the activation of the HIF-1 pathway in cancer treatment through different targets ENSG00000198793 ENSG00000126838 ENSG00000175104 ENSG00000168610 PMC7476086__F8 Proposed schematic model: CRISPR/Cas9-mediated knockout of SHP2 inhibits breast cancer proliferation by regulating Cyclin D1 stability via the PI3K/AKT/GSK3B signaling pathway PMC5394831__F3 GnRH signaling pathway containing PLCB1 and MAP2K6 ENSG00000087245 ENSG00000070831 PMC6072563__F1 Schematic represents various signaling pathways that occur within tumor cells, which allow for cell growth, proliferation, and invasion ENSG00000135446 ENSG00000105810 ENSG00000168610 ENSG00000146648 PMC2747760__F1 Leptin signaling: A key pathway in immune responses ENSG00000115415 ENSG00000169047 ENSG00000168610 PMC3903477__F1 Characterization of Cyanobacterial Hydrocarbon Composition and Distribution of Biosynthetic Pathways ENSG00000134575 PMC4121847__F6 Diagram illustrating the proposed pathway by which TLR4/caspase-8/inflammasome up-regulation induces the processing of IL-1B and promotes the inflammatory response in acute glaucoma ENSG00000162711 ENSG00000091592 PMC7352588__F3 DUBs Activating the Hedgehog Signaling Pathway: A Promising Therapeutic Target in Cancer ENSG00000150991 PMC8101316__F1 Proposed Parkinson Disease Genetic Testing Pathway ENSG00000158828 PMC7352588__F1 Hedgehog signaling pathway ENSG00000106571 ENSG00000128602 PMC9490146__F3 Targeting cellular senescence to combat cancer and ageing ENSG00000183735 ENSG00000164430 ENSG00000111537 PMC6017243__F9 The above-mentioned findings ENSG00000005882 PMC7352588__F4 E3-ubiquitin ligases and DUBs involved in Smo regulation ENSG00000291431 ENSG00000128602 ENSG00000148634 PMC8262770__F2 Metabolic Control of Smoldering Neuroinflammation ENSG00000131473 ENSG00000168329 ENSG00000011600 ENSG00000135218 ENSG00000198793 ENSG00000079432 ENSG00000183160 PMC11880738__F1 Mechanisms responsible for copper uptake and homeostasis in cells ENSG00000173992 ENSG00000138495 ENSG00000123191 ENSG00000166260 ENSG00000177556 ENSG00000133028 ENSG00000284194 PMC10189745__F1 IL-36 signaling pathway ENSG00000136694 ENSG00000172936 ENSG00000175104 PMC6521881__F2 Network of Neurotrophin signaling pathway ENSG00000169047 ENSG00000169032 PMC8392047__F1 Selective Autophagy in Hyperglycemia-Induced Microvascular and Macrovascular Diseases ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000128272 ENSG00000126775 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC5557744__F11 Schematic summary of the interleukin-6 (IL-6)/STAT3 signaling pathway, highlighting its central role in regulating the expression of multiple genes and cellular functions in metastatic breast cancer cells ENSG00000168610 PMC4813224__F3 Argininosuccinate synthetase (ASS)-negative cell death induced by arginine deprivation ENSG00000198793 PMC6500763__F1 Signaling cascades involving EGR1, PTEN, DMP1, ARF, and the p53 network ENSG00000105327 ENSG00000105329 PMC8714937__F4 LKB1 Regulates Vascular Macrophage Functions in Atherosclerosis ENSG00000125538 ENSG00000198793 PMC6262272__F7A Mechanical Stretching Simulates Cardiac Physiology and Pathology through Mechanosensor Piezo1 ENSG00000281324 ENSG00000168036 ENSG00000103335 PMC8255928__F5 Integrative Analysis of lncRNA-mRNA Profile Reveals Potential Predictors for SAPHO Syndrome ENSG00000165801 ENSG00000205903 ENSG00000206560 ENSG00000172322 ENSG00000284774 ENSG00000254206 ENSG00000137494 ENSG00000092931 ENSG00000161405 ENSG00000204977 ENSG00000158869 ENSG00000178896 ENSG00000129071 ENSG00000105197 ENSG00000054690 ENSG00000008513 ENSG00000152601 ENSG00000172667 ENSG00000129038 ENSG00000172939 ENSG00000163683 ENSG00000278308 ENSG00000145819 ENSG00000127507 ENSG00000188227 PMC5668145__F5 Steady-state levels of TCA intermediates in control and KO livers and tumors and the expression of key enzymes in the glutaminolysis pathway ENSG00000135423 ENSG00000141086 ENSG00000062485 PMC5606117__F4 Crosstalk between the genes (in blue) obtained from the systematic review of LR and their biological functions in the dopaminergic neurons ENSG00000006071 ENSG00000150991 ENSG00000291971 ENSG00000010810 ENSG00000102468 ENSG00000149295 PMC8533862__F8 Comparative Analysis of Six IRF Family Members in Alveolar Epithelial Cell-Intrinsic Antiviral Responses ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000168310 ENSG00000125347 ENSG00000276561 PMC3640510__F2 Diagram representing possible mechanisms linking HCV-induced oxidative stress with hepatocarcinogenesis ENSG00000116133 ENSG00000140398 PMC3367861__F2 IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasis ENSG00000125266 ENSG00000090776 ENSG00000105639 ENSG00000168685 PMC2980759__F1 Examples of the inter-relationship between host, tumor, and environmental factors (pharmaco-epi-bio-genomic triad) that determine the response to tamoxifen in an individual patient (phenotype) ENSG00000196502 ENSG00000291971 PMC11893596__F3 MLKL-related pathophysiological events in the endoplasmic reticulum and nucleus ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC11893596__F2 Pathophysiological actions of MLKL in the lysosome and endosome ENSG00000081041 ENSG00000163739 ENSG00000198793 ENSG00000189403 ENSG00000168404 ENSG00000285379 PMC5216741__F6 MicroRNA-1291 targets the FOXA2-AGR2 pathway to suppress pancreatic cancer cell proliferation and tumorigenesis ENSG00000182809 ENSG00000105835 ENSG00000198793 ENSG00000135069 ENSG00000171345 ENSG00000101365 ENSG00000106546 ENSG00000127884 ENSG00000109814 ENSG00000162385 ENSG00000143320 ENSG00000132646 ENSG00000171759 PMC3367861__F1 IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasis ENSG00000070831 ENSG00000149269 ENSG00000150907 ENSG00000105639 PMC5807041__F11 Top deregulated networks in NL-20 cells: Hematological system development and function, immunological disease, lymphoid tissue structure and development network induced by Caki-2 cells defined by Ingenuity Pathway Analysis ENSG00000166167 ENSG00000138639 ENSG00000112964 ENSG00000196549 ENSG00000100142 ENSG00000119919 ENSG00000147601 ENSG00000134909 ENSG00000278211 ENSG00000138738 PMC4997391__F4 Urinary Metabolomic Approach Provides New Insights into Distinct Metabolic Profiles of Glutamine and N-Carbamylglutamate Supplementation in Rats ENSG00000173599 PMC5807041__F12 Significantly deregulated networks in NL-20 cells: Cell-to-cell signaling and interaction, connective tissue disorder and developmental disorder induced by Caki-2 cells defined by Ingenuity Pathway Analysis ENSG00000183287 ENSG00000170075 ENSG00000162923 ENSG00000179528 ENSG00000184956 ENSG00000137198 ENSG00000131351 ENSG00000072274 ENSG00000285199 ENSG00000152926 ENSG00000176971 ENSG00000284984 PMC8542015__F3 Probiotics Interactions and the Modulation of Major Signalling Pathways in Host Model Organism Caenorhabditis elegans ENSG00000129347 ENSG00000168036 PMC6073630__F3 Disruption of ncRNA Networks in Cancer ENSG00000144535 ENSG00000039537 ENSG00000101751 ENSG00000112242 ENSG00000150907 ENSG00000166169 ENSG00000123908 PMC5807041__F17 Deregulated networks in NL-20 cells: Cell-to-cell signaling and interaction, connective tissue disorder, developmental disorder networks induced by ACHN cells defined by Ingenuity Pathway Analysis ENSG00000118058 ENSG00000147162 ENSG00000168214 ENSG00000111727 ENSG00000076924 ENSG00000125686 ENSG00000141568 ENSG00000160360 ENSG00000072364 ENSG00000162896 PMC2224366__F9 Innate immune modulation of CTL response to LCMV through MyD88 signaling ENSG00000239732 ENSG00000172936 PMC7499473__F1 Targeting CXCR4 ENSG00000178860 ENSG00000107562 ENSG00000198793 ENSG00000121966 PMC9247256__F6 Alterations of Cardiac Protein Kinases in Cyclic Nucleotide-Dependent Signaling Pathways in Human Ischemic Heart Failure ENSG00000291931 ENSG00000124614 ENSG00000067057 ENSG00000068976 ENSG00000156482 ENSG00000149273 ENSG00000152556 PMC6759650__F5 Enrichment in multiple cancer-associated networks in breast cancer ENSG00000135549 ENSG00000087510 ENSG00000151725 ENSG00000125931 ENSG00000111057 ENSG00000077152 ENSG00000133985 ENSG00000160182 ENSG00000129514 ENSG00000171345 ENSG00000004478 ENSG00000248905 ENSG00000156802 ENSG00000003989 ENSG00000143126 ENSG00000162105 ENSG00000100219 ENSG00000183779 ENSG00000196208 ENSG00000106078 PMC6759650__F4 Mechanistic network analysis predicts multiple affected signaling networks ENSG00000087510 ENSG00000115457 ENSG00000150907 ENSG00000177606 ENSG00000101057 ENSG00000168036 ENSG00000185591 ENSG00000146648 ENSG00000124762 PMC5489426__F2 Dual role of cellular prion protein in normal host and Alzheimer’s disease ENSG00000291971 ENSG00000010810 PMC5779965__F5 Confirmation of some miRNA and target gene expression and integrative pathway analysis ENSG00000169291 ENSG00000135446 ENSG00000166147 PMC1785339__F4 Human and mouse mutations and the cognitive disorders affecting specific NRC/MASC signaling pathways and other postsynaptic proteins ENSG00000147044 ENSG00000125675 ENSG00000178568 PMC8229583__F7 17B Estradiol Rescued Immature Rat Brain against Glutamate-Induced Oxidative Stress and Neurodegeneration via Regulating Nrf2/HO-1 and MAP-Kinase Signaling Pathway ENSG00000131095 ENSG00000102003 ENSG00000167419 PMC6315507__F2 Intermediary thiol metabolism in renal proximal tubular cells ENSG00000197299 ENSG00000040531 PMC5470994__F3 DE genes are significantly overrepresented in the Toll-like receptor signaling pathway ENSG00000171855 ENSG00000213928 ENSG00000105327 ENSG00000089127 ENSG00000163743 ENSG00000157601 ENSG00000160710 ENSG00000168811 ENSG00000121879 ENSG00000183735 ENSG00000088888 ENSG00000078900 ENSG00000117335 ENSG00000113520 ENSG00000026103 ENSG00000109320 ENSG00000115267 ENSG00000213341 ENSG00000168610 ENSG00000276561 ENSG00000143387 ENSG00000111537 ENSG00000115415 ENSG00000010810 ENSG00000079435 ENSG00000090659 PMC8310949__F3 WNT3A rs752107(C > T) Polymorphism Is Associated With an Increased Risk of Essential Hypertension and Related Cardiovascular Diseases ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5808968__F1 KEGG database illustration of the MAP kinase pathway ENSG00000138798 ENSG00000146648 PMC5281575__F1 Metabolic control of macrophage activation ENSG00000131473 ENSG00000113520 ENSG00000136869 PMC5855670__F2 Death ligand pathway ENSG00000102871 ENSG00000168040 PMC9007636__F4 Expression Profiles of HOXC6 Predict the Survival of Glioblastoma Patients and Correlate with Cell Cycle ENSG00000144063 ENSG00000108582 ENSG00000105664 ENSG00000187682 ENSG00000197757 PMC4281031__F3 PI3K-AKT-mTOR signalling pathway and associated hamartoma/overgrowth syndromes (PI3K subsumes PIK3CA and PIK3R2, AKT subsumes AKT1-3) ENSG00000198793 PMC5812543__F1 Isoprenoid formation ENSG00000067064 ENSG00000197429 PMC10420029__F12 mTOR signaling pathway of P ENSG00000168003 ENSG00000198793 ENSG00000163914 ENSG00000118515 ENSG00000155792 ENSG00000164327 ENSG00000176641 ENSG00000285069 PMC10420029__F11 Fanconi anemia pathway of P ENSG00000012061 ENSG00000154920 ENSG00000077152 ENSG00000188827 ENSG00000012048 ENSG00000175054 ENSG00000144554 ENSG00000108384 ENSG00000162607 ENSG00000051180 ENSG00000276787 ENSG00000164053 ENSG00000101751 ENSG00000181544 ENSG00000197774 ENSG00000187790 ENSG00000115392 ENSG00000187741 ENSG00000112039 ENSG00000158169 ENSG00000139618 ENSG00000131944 ENSG00000175643 ENSG00000197299 ENSG00000178966 ENSG00000114315 ENSG00000122678 ENSG00000122512 ENSG00000122008 PMC3355730__F2 Co-expression of genes involved in lignin formation across species ENSG00000038382 ENSG00000157933 ENSG00000084774 PMC7855707__F2 In the absence of IFN (left), constitutively internalized IFNAR1 and IFNAR2 subunits may recycle from the sorting endosome to the PM ENSG00000112335 ENSG00000205302 ENSG00000129515 ENSG00000111237 ENSG00000069329 ENSG00000028528 ENSG00000142166 PMC8211811__F4 DCBLD1 is associated with the integrin signaling pathway and has prognostic value in non-small cell lung and invasive breast carcinoma ENSG00000162627 ENSG00000164932 ENSG00000087245 ENSG00000166130 ENSG00000155254 ENSG00000102359 ENSG00000164465 ENSG00000150093 ENSG00000168487 ENSG00000122786 ENSG00000089159 ENSG00000047932 ENSG00000087253 ENSG00000011422 ENSG00000145623 ENSG00000134013 ENSG00000157227 ENSG00000196923 ENSG00000011028 ENSG00000072110 ENSG00000196639 ENSG00000137076 ENSG00000006327 ENSG00000139278 PMC6584916__F4 Downstream targets of Slit/Robo ENSG00000145147 ENSG00000170558 ENSG00000154134 ENSG00000185008 PMC10944040__F1 Molecular mechanisms of IL‐1 release ENSG00000278718 ENSG00000162711 ENSG00000125538 ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000115594 PMC6584916__F1 Structure of the Slit/Robo protein family and their interaction ENSG00000154133 ENSG00000154134 ENSG00000185008 PMC10944040__F3 Antagonism of IL‐1 signaling pathway ENSG00000115590 ENSG00000172936 ENSG00000115594 PMC3409287__F3 ITIM-mediated signaling function of IDO ENSG00000104856 ENSG00000010810 ENSG00000184216 PMC6584916__F7 Roles of Slit/Robo in angiogenesis ENSG00000145147 ENSG00000154133 ENSG00000107731 PMC5480214__F2 Summary of ergot-alkaloid biosynthetic pathways with emphasis on Clavicipitaceae PMC10944040__F2 IL‐1 signaling pathway ENSG00000125538 ENSG00000172936 ENSG00000184216 ENSG00000115594 PMC6584916__F6 Roles of Slit/Robo in neurocyte navigation ENSG00000125848 ENSG00000291971 ENSG00000154134 ENSG00000185008 PMC6584916__F5 Upstream regulatory molecules of Slit/Robo ENSG00000145147 ENSG00000077254 ENSG00000184347 ENSG00000074266 ENSG00000154134 ENSG00000178691 ENSG00000185008 ENSG00000140464 PMC7176443__F3 Functional lncRNAs in signaling pathway ENSG00000070831 ENSG00000173039 PMC12234997__F5 Protein-protein interaction (PPI) network analysis related to IMP and IMF and identification of their major effect genes ENSG00000243364 ENSG00000163083 ENSG00000100385 ENSG00000157184 ENSG00000144644 ENSG00000138755 ENSG00000147162 ENSG00000108515 ENSG00000137033 ENSG00000125347 ENSG00000007171 ENSG00000172508 ENSG00000183648 ENSG00000135643 ENSG00000109270 ENSG00000115361 ENSG00000154188 ENSG00000166123 ENSG00000113448 ENSG00000152556 ENSG00000168685 ENSG00000101670 ENSG00000130957 ENSG00000107562 ENSG00000135218 ENSG00000221914 ENSG00000156885 ENSG00000184508 ENSG00000197442 ENSG00000099942 ENSG00000112715 ENSG00000147123 ENSG00000138764 ENSG00000125538 ENSG00000277236 ENSG00000118515 ENSG00000100504 ENSG00000167701 ENSG00000132906 ENSG00000184983 ENSG00000115221 ENSG00000198626 ENSG00000134871 ENSG00000182621 ENSG00000006534 ENSG00000225950 ENSG00000129048 ENSG00000148660 ENSG00000067606 ENSG00000174233 ENSG00000114268 ENSG00000133805 PMC7998429__F3 Nail organ markers and the requirement of the bone morphogenetic protein (BMP) signaling in proper nail development and differentiation ENSG00000133067 ENSG00000203782 ENSG00000139289 PMC5822808__F1 Overview of Hippo-Yap signaling pathway ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC4709767__F6 Proposed pathways by which NRG-1 stimulates GSH synthesis and Cbl metabolism ENSG00000124102 ENSG00000110395 PMC11697911__F7 Graphical overview of the canonical role and potential regulatory mechanisms of the Notch signaling pathway on porcine oocyte maturation ENSG00000135547 ENSG00000128917 ENSG00000069812 ENSG00000184916 ENSG00000114315 ENSG00000090932 PMC3346990__F3 The potential molecular mechanisms of crosstalk between nuclear receptors LXR and FXR–SHP–LRH-1 regulatory cascade in the liver and intestine ENSG00000160867 ENSG00000167910 PMC6013567__F2 Activation of the anticipatory unfolded protein response by estrogen receptor A (ERA) ENSG00000144895 ENSG00000284161 ENSG00000167658 PMC3623797__F7 Type I IFN Triggers RIG-I/TLR3/NLRP3-dependent Inflammasome Activation in Influenza A Virus Infected Cells ENSG00000162711 ENSG00000088888 ENSG00000125538 ENSG00000121060 ENSG00000164342 ENSG00000142166 PMC4212479__F1 Sphingolipid metabolism ENSG00000139624 ENSG00000100422 ENSG00000154227 ENSG00000102172 ENSG00000143418 PMC9650140__F1 Pathology and molecular mechanisms of Schistosoma japonicum-associated liver fibrosis ENSG00000145604 ENSG00000108821 ENSG00000168610 PMC4875603__F6 Expression of genes that function in leukocyte activation in uninfected fetuses ENSG00000138207 ENSG00000175206 ENSG00000288411 ENSG00000042832 ENSG00000118785 ENSG00000158887 ENSG00000100985 ENSG00000147588 ENSG00000101425 ENSG00000090659 PMC8450769__F10 Albuca Bracteate Polysaccharides Synergistically Enhance the Anti-Tumor Efficacy of 5-Fluorouracil Against Colorectal Cancer by Modulating Beta-Catenin Signaling and Intestinal Flora ENSG00000132646 ENSG00000168036 PMC6770018__F6 The key carbohydrate metabolic pathway and the miRNA–mRNA interactions in dmc ENSG00000159224 ENSG00000118094 ENSG00000167701 PMC9346324__F2 Retrospective analysis of endocrine disease in sphingosine-1-phosphate lyase insufficiency: case series and literature review ENSG00000139624 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000173599 ENSG00000102172 ENSG00000143418 PMC6263089__F4 MTOR/S6K intracellular signal transduction pathways in the osteoclast ENSG00000002330 ENSG00000070831 ENSG00000291971 ENSG00000198793 ENSG00000119408 ENSG00000175104 ENSG00000127191 PMC3467356__F1 Regulatory network analysis of the top genes with SNPs with p<0.001 using MetaCore’s shortest pathway algorithm (GeneGo Inc.); the nodes that are circled are the genes of interest ENSG00000151490 ENSG00000140968 ENSG00000185591 PMC9279119__F3 Periodontal Pathogens: A Crucial Link Between Periodontal Diseases and Oral Cancer ENSG00000087095 ENSG00000100985 PMC4113827__F2 TLR4 signaling pathway ENSG00000170458 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC2944875__F2 Gene Expression Study of Monocytes/Macrophages during Early Foreign Body Reaction and Identification of Potential Precursors of Myofibroblasts ENSG00000141232 ENSG00000169554 ENSG00000157933 ENSG00000111537 ENSG00000005339 ENSG00000138798 ENSG00000183691 ENSG00000177606 ENSG00000164399 ENSG00000167074 ENSG00000104432 ENSG00000137801 PMC3560666__F7 Pathway in MAS and differentially expressed genes: as shown in Figure, IGSF4, PTPRC (CD45) and CD3D belong to a family of cell surface adhesion molecules ENSG00000023445 ENSG00000081237 ENSG00000105656 ENSG00000142273 ENSG00000150637 ENSG00000115760 ENSG00000278624 ENSG00000163421 ENSG00000125538 ENSG00000272398 ENSG00000184371 ENSG00000164400 ENSG00000005381 PMC7188750__F4 Application of microbial extracellular carbohydrate polymeric substances in food and allied industries PMC8821549__F3 TR-binding and regulation of genes in the hedgehog signaling pathway in intestine based on ChIP-Seq and RNA-Seq data ENSG00000164161 ENSG00000166813 ENSG00000121067 ENSG00000171791 ENSG00000128602 PMC4735514__F2 Activation of the methylation cycle in cells reprogrammed into a stem cell-like state ENSG00000116761 ENSG00000133027 PMC9558279__F1 PTH, FGF-23, Klotho and Vitamin D as regulators of calcium and phosphorus: Genetics, epigenetics and beyond ENSG00000152266 ENSG00000081189 ENSG00000087460 PMC8304173__F4 Therapies Targeting Metabolic Pathways in Cancer Stem Cells ENSG00000157184 ENSG00000131473 ENSG00000169710 ENSG00000263163 ENSG00000275565 ENSG00000168610 PMC8304173__F2 Therapies Targeting Metabolic Pathways in Cancer Stem Cells ENSG00000074800 ENSG00000136997 ENSG00000143995 PMC4307326__F5 Some possible signaling pathways activated by SF-CSNPs which may regulate metabolism of proliferating cells through Ubiquitin C (UBC) ENSG00000137275 ENSG00000198793 ENSG00000131323 ENSG00000146648 PMC4307326__F4 Protein–protein interaction pathways are illustrated ENSG00000117713 ENSG00000150991 ENSG00000198793 ENSG00000126001 ENSG00000100813 ENSG00000121879 ENSG00000115760 PMC5358695__F4 Layered network between rituximab and myasthenia gravis (MG) ENSG00000203747 ENSG00000072694 ENSG00000150337 ENSG00000166278 ENSG00000143226 PMC5358695__F3 Identifying myasthenia gravis (MG) risk genes regulated by drugs and miRNAs in the hsa05200 pathway ENSG00000134982 ENSG00000099942 ENSG00000128602 ENSG00000132341 PMC5358695__F6 Layered network between sunitinib and myasthenia gravis (MG) ENSG00000157404 ENSG00000157764 ENSG00000171791 ENSG00000112715 ENSG00000117322 ENSG00000122025 ENSG00000226275 ENSG00000111537 ENSG00000122756 ENSG00000128052 ENSG00000136997 ENSG00000134853 ENSG00000196352 ENSG00000037280 ENSG00000178568 ENSG00000026103 PMC5358695__F5 Layered network between adalimumab and MG ENSG00000203747 ENSG00000111537 ENSG00000157764 ENSG00000072694 ENSG00000277263 ENSG00000166278 ENSG00000143226 ENSG00000162747 ENSG00000182326 ENSG00000026103 PMC3427262__F1 Crosstalk between the UPR and autophagy pathway contributes to handling cellular stress in neurodegenerative disease ENSG00000128272 ENSG00000144895 ENSG00000150907 ENSG00000171791 ENSG00000127191 ENSG00000145782 ENSG00000057663 PMC5358695__F7 Layered network between muromonab and myasthenia gravis (MG) ENSG00000134460 ENSG00000157764 ENSG00000198851 ENSG00000163599 ENSG00000143226 ENSG00000117322 ENSG00000188389 ENSG00000203747 ENSG00000224320 ENSG00000072694 ENSG00000113520 ENSG00000277263 ENSG00000026103 PMC8875223__F1 Cellular Metabolism during Candida-Host Interactions ENSG00000162711 ENSG00000074800 ENSG00000136997 ENSG00000049768 ENSG00000122194 ENSG00000026103 PMC11666815__F1 Schematic illustration of the natural compound–induced protective effects against CVD damage through AMPK/SIRT1/PGC‐1A signaling pathway ENSG00000162711 ENSG00000106459 PMC8811971__F1 IKK-mediated CYLD phosphorylation and cellular redox activity ENSG00000137275 ENSG00000083799 ENSG00000079999 PMC3152294__F1 Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism ENSG00000135547 ENSG00000148400 ENSG00000074181 ENSG00000273529 ENSG00000114315 PMC5671973__F1 Recognition of human immunodeficiency virus 1 (HIV-1) by innate immune system ENSG00000088888 ENSG00000172936 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC10036758__F1 The complosome in health and disease ENSG00000039537 ENSG00000009724 ENSG00000117335 ENSG00000166278 ENSG00000117322 ENSG00000182326 ENSG00000236625 PMC1448211__F7 Real time pathway analysis of cell-cycle related genes mediated via TS overexpression in HCT-C18 (TS+) cells using actual gene expression data ENSG00000175054 ENSG00000142192 ENSG00000105669 PMC11033207__F10 Redox signaling and skeletal muscle adaptation during aerobic exercise ENSG00000261371 ENSG00000086991 ENSG00000096717 PMC9633954__F2 Pattern recognition receptor signaling and innate immune responses to schistosome infection ENSG00000162711 PMC9101426__F2 Copy Number Alterations as Novel Biomarkers and Therapeutic Targets in Colorectal Cancer ENSG00000019991 ENSG00000198793 ENSG00000136997 ENSG00000121879 ENSG00000168610 PMC3117317__F3 NFKB signaling pathway ENSG00000104856 ENSG00000163235 ENSG00000138798 ENSG00000132692 ENSG00000173039 ENSG00000111321 PMC7137714__F6 Identification of microRNA-mRNA regulatory networks and pathways related to retinoblastoma across human and mouse ENSG00000023445 ENSG00000089685 ENSG00000129355 ENSG00000135476 ENSG00000112742 ENSG00000282899 PMC2662580__F1 Wnt therapy for bone loss: golden goose or Trojan horse? ENSG00000156076 ENSG00000134982 ENSG00000168036 ENSG00000125084 PMC7539779__F6 Mechanism by which SLFN5 regulates BRCA progression ENSG00000166750 PMC9184225__F6 Improvement of Biosynthetic Ansamitocin P-3 Production Based on Oxygen-Vector Screening and Metabonomics Analysis ENSG00000159224 ENSG00000122966 ENSG00000172005 PMC5686191__F8 Possible mechanisms underlying how YAP regulated LRP1 by promoting proliferation and metastasis of melanoma cells and also reducing apoptosis ENSG00000087245 ENSG00000100985 PMC3459659__F1 Lipopolysaccharide/TLR4 signalling lipopolysaccharide recognition.Notes: Overview of LPS/TLR4 signalling LPS recognition is facilitated by lipopolysaccharide-binding protein and CD14, and is mediated by TLR4/MD-2 receptor complex ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC3762672__F1 PI3-K signaling.Notes: Activation of class I PI3-K via RTK phosphorylates and activates downstream target PDK1, in turn phosphorylating AKT kinases at the threonine site PMC8151225__F9 3,3′-Diindolylmethane Suppresses the Growth of Hepatocellular Carcinoma by Regulating Its Invasion, Migration, and ER Stress-Mediated Mitochondrial Apoptosis ENSG00000170558 PMC4364827__F3 Activation of the DNA damage response (DDR) after DNA double-strand breaks (DSB) induction in young and old cells ENSG00000188486 ENSG00000149311 ENSG00000163961 ENSG00000197299 ENSG00000112130 PMC4454381__F4 Regulation of autophagy by protein post-translational modification ENSG00000147162 ENSG00000198408 ENSG00000197386 PMC150988__F1 JAK-STAT signaling and the generation of Th1 and Th2 cells ENSG00000138378 PMC3648520__F1 Roles of DNA Helicases in the Mediation and Regulation of Homologous Recombination ENSG00000115008 ENSG00000197299 ENSG00000051180 ENSG00000178966 ENSG00000139618 PMC4835209__F8 Conceptual schematic of the miRNA signal pathway regulated by TGFB2-OT1 in autophagy and inflammation ENSG00000116001 ENSG00000185818 ENSG00000155506 ENSG00000223802 ENSG00000125538 ENSG00000198793 ENSG00000144848 ENSG00000284099 ENSG00000173039 ENSG00000176046 PMC8957988__F2 An Update of Long-Noncoding RNAs in Acute Kidney Injury PMC7429250__F3 Hypoxia-mediated glucose metabolism promotes dynamic O-GlcNAcylation of G6PD facilitating the utilization of PPP to produce NADPH for ROS detoxification ENSG00000134086 ENSG00000147162 ENSG00000086991 PMC6507272__F3 Role and expression of proteins identified by proteomic analysis within NAD+ metabolism and signaling pathway ENSG00000077009 ENSG00000204653 ENSG00000105835 ENSG00000291814 ENSG00000152620 ENSG00000278488 ENSG00000157064 ENSG00000112874 ENSG00000112992 ENSG00000008130 ENSG00000106733 PMC11657277__F9 Function and mechanisms of Chiglitazar in CML cells ENSG00000067057 ENSG00000198793 ENSG00000159399 PMC9602982__F2 Impacts of Cholesterol, Oxysterols, and Cholesterol Lowering Dietary Compounds on the Immune System ENSG00000172893 ENSG00000113161 PMC3370667__F1 Schema of the FUS1 pathway ENSG00000132906 ENSG00000138798 ENSG00000120868 ENSG00000146648 PMC6090437__F7 Kyoto Encyclopedia of Genes and Genomes pathway analysis of the hub gene secreted LY6/PLAUR domain and its connected genes ENSG00000164754 ENSG00000116717 ENSG00000189308 ENSG00000091651 ENSG00000277273 ENSG00000121774 ENSG00000124762 PMC8482240__F3 Comprehensive Proteomic Analysis of Colon Cancer Tissue Revealed the Reason for the Worse Prognosis of Right-Sided Colon Cancer and Mucinous Colon Cancer at the Protein Level ENSG00000104365 ENSG00000009724 ENSG00000109320 ENSG00000113140 ENSG00000288335 ENSG00000168067 ENSG00000197442 ENSG00000244731 ENSG00000213341 ENSG00000169032 ENSG00000127191 ENSG00000176919 ENSG00000236625 ENSG00000157131 ENSG00000274619 ENSG00000126803 ENSG00000122691 PMC6368612__F4 Wnt signaling pathway ENSG00000134982 ENSG00000168036 ENSG00000125084 PMC3532379__F3 Functional “DASE” networks ENSG00000137674 ENSG00000187908 ENSG00000250254 ENSG00000129204 PMC4260922__F2 Transcriptomic Immune Response of the Cotton Stainer Dysdercus fasciatus to Experimental Elimination of Vitamin-Supplementing Intestinal Symbionts ENSG00000172936 ENSG00000130159 PMC8217552__F4 Autophagy induction limits SARS-CoV-2 growth in vitro ENSG00000145604 ENSG00000177169 ENSG00000288145 ENSG00000112561 ENSG00000145782 ENSG00000057663 PMC7179076__F2 Wild type (wt) p53 and mutant (mut) p53 expressed in tumor cells on anti-tumor immune responses and inflammation ENSG00000163220 ENSG00000102970 ENSG00000168610 PMC3152494__F7 The crosstalk between the NOTCH and AKT pathways at the molecular and cellular levels ENSG00000117400 PMC8630185__F1 Hemodialysis biocompatibility mathematical models to predict the inflammatory biomarkers released in dialysis patients based on hemodialysis membrane characteristics and clinical practices ENSG00000110799 ENSG00000288512 ENSG00000166278 ENSG00000182326 PMC10473147__F2 Neuroinflammation: A Common Pathway in Alzheimer’s Disease and Epilepsy ENSG00000125538 ENSG00000129226 ENSG00000131095 PMC9521765__F1 Free-cell therapeutics and mechanism of exosomes from adipose-derived stem cells in promoting wound healing: current understanding and future applications ENSG00000134982 ENSG00000168036 ENSG00000168610 PMC8027653__F1 BAP1-mediated malignant signaling ENSG00000163930 ENSG00000172534 ENSG00000145386 ENSG00000080839 PMC6158072__F23 Nrf2/AR signaling is at the crossroads of Wnt and Akt/FOXO signaling pathways ENSG00000168036 ENSG00000079999 PMC7720132__F6 Summary of major impacts of challenge with Vibrio coralliilyticus RE22 and probiotic treatments with Bacillus pumilus RI06–95 and Phaoebacter inhibens S4 on Crassostrea virginica larval immune responses ENSG00000175104 ENSG00000198925 PMC9170600__F1 Effects of nicotinamide adenine dinucleotide in cardiovascular diseases: Molecular mechanisms, roles and therapeutic potential ENSG00000105835 ENSG00000123572 ENSG00000278488 PMC9088190__F1 Methods for monitoring cancer cell pyroptosis ENSG00000278718 ENSG00000162711 ENSG00000015285 ENSG00000189403 ENSG00000147697 ENSG00000073605 PMC5943908__F6 Summary of the vasoconstriction signal transduction pathways showing points of intervention by Xyl-B ENSG00000093217 PMC8667473__F2 Review: The Role of Wnt/Beta-Catenin Signalling in Neural Crest Development in Zebrafish ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC8909674__F4 Mitochondrial Stress Response in Cancer Progression ENSG00000177169 ENSG00000123395 ENSG00000083290 ENSG00000144848 ENSG00000158828 ENSG00000069509 ENSG00000145782 ENSG00000057663 PMC2658594__F4 AHR-dependent misregulation of Wnt signaling disrupts tissue regeneration ENSG00000281324 ENSG00000125398 ENSG00000168036 PMC3549305__F4 GLUTATHIONE SYNTHESIS PMC11373551__F8 Identification of core regulatory genes and construction of partial correlation interaction networks related to taurine metabolism pathways ENSG00000019582 ENSG00000142192 ENSG00000128016 ENSG00000134982 ENSG00000163739 ENSG00000010810 ENSG00000156738 ENSG00000107175 ENSG00000073756 ENSG00000277943 ENSG00000113360 PMC6468754__F1 Hypoxia inducible factor (HIF) and vascular endothelial growth factor (VEGF) link the angiogenesis signaling pathways ENSG00000162692 PMC8482240__F7 Comprehensive Proteomic Analysis of Colon Cancer Tissue Revealed the Reason for the Worse Prognosis of Right-Sided Colon Cancer and Mucinous Colon Cancer at the Protein Level ENSG00000026297 ENSG00000064601 ENSG00000101160 ENSG00000100448 ENSG00000145384 ENSG00000197746 ENSG00000213614 ENSG00000196743 ENSG00000172009 ENSG00000163751 ENSG00000135678 ENSG00000137509 ENSG00000117054 ENSG00000166562 ENSG00000196549 ENSG00000123213 ENSG00000130234 ENSG00000291387 ENSG00000134121 ENSG00000263238 PMC5677954__F6 Osteoblastic differentiation-related molecular mechanism under combined cytokine treatment ENSG00000170365 ENSG00000198793 ENSG00000168036 PMC4875603__F4 T Cell Receptor (TCR) signaling pathway activation in endometrium of UNINF fetuses ENSG00000107338 ENSG00000213658 ENSG00000010810 ENSG00000185591 ENSG00000135605 PMC8299113__F1 Gold Nanomaterials and Bone/Cartilage Tissue Engineering: Biomedical Applications and Molecular Mechanisms ENSG00000168036 PMC8081922__F5 Beta-Catenin mediates glucose-dependent insulinotropic polypeptide increases in lysyl oxidase expression in osteoblasts ENSG00000159224 ENSG00000168036 ENSG00000010310 PMC4130595__F3 Identifying a Polymorphic ‘Switch’ That Influences miRNAs' Regulation of a Myasthenia Gravis Risk Pathway ENSG00000171791 ENSG00000140443 PMC8169871__F2 Alterations in brain metabolite concentrations and brain gene expression in AD ENSG00000110921 ENSG00000112972 ENSG00000172893 ENSG00000167910 ENSG00000113161 ENSG00000120437 ENSG00000167508 ENSG00000160752 ENSG00000138135 ENSG00000001630 ENSG00000116133 ENSG00000109929 ENSG00000149809 ENSG00000036530 ENSG00000015285 ENSG00000104549 ENSG00000135929 PMC5490603__F3 Anti-inflammatory signaling pathways influenced by free zinc ENSG00000134460 ENSG00000170365 ENSG00000105639 PMC5490603__F2 Pro-inflammatory signaling pathway influences by zinc ENSG00000102871 ENSG00000134070 ENSG00000172936 ENSG00000049768 ENSG00000175104 ENSG00000168610 ENSG00000184216 PMC5490603__F1 Activation of Toll-like receptor (TLR) signaling pathways is mediated by a complex array of proteins ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC7288943__F8 Schematic diagram showing the mechanisms by which S58 promotes antioxidant defense of HConFs against fibrosis PMC8923649__F5 Correlation of SARS-CoV-2 to cancer: Carcinogenic or anticancer? (Review) ENSG00000002330 ENSG00000130234 ENSG00000184012 PMC7868705__F1 Noncanonical NFKB Signaling Pathway in Liver Diseases ENSG00000104856 ENSG00000125538 ENSG00000173039 ENSG00000131323 PMC2679904__F1 TLR mediated signaling ENSG00000183735 ENSG00000172936 ENSG00000157625 ENSG00000168310 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC8969450__F2 Platelet-leukocyte crosstalk in COVID-19: How might the reciprocal links between thrombotic events and inflammatory state affect treatment strategies and disease prognosis? ENSG00000239732 ENSG00000130234 ENSG00000125538 ENSG00000184012 ENSG00000197943 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000168610 PMC7794007__F1 Diagrams depicting the Sestrins-mediated stress signaling pathways and functional domains of Sestrin2 in the regulation of metabolism and disease ENSG00000177169 ENSG00000100387 ENSG00000169047 ENSG00000178828 ENSG00000079999 PMC3874163__F8 A simplified view of siRNA-enhanced DNA-mediated IFN-λ1 signalling pathway ENSG00000183735 ENSG00000088888 ENSG00000163565 PMC8473587__F1 p53 regulates glucose, lipid, amino acid, nucleotide, and iron metabolism ENSG00000152782 ENSG00000151012 ENSG00000165349 ENSG00000005882 ENSG00000105697 ENSG00000070669 ENSG00000180210 ENSG00000182511 ENSG00000155287 ENSG00000092621 ENSG00000136997 ENSG00000167325 ENSG00000161513 ENSG00000171848 ENSG00000078237 ENSG00000171951 ENSG00000124253 ENSG00000159399 ENSG00000005469 PMC6925522__F2 LRRK2 and inflammatory signalling ENSG00000159200 ENSG00000125538 ENSG00000136869 ENSG00000091106 ENSG00000175104 ENSG00000276068 PMC3148026__F2 Pathway alterations involved in the development of low-grade serous carcinoma ENSG00000157764 ENSG00000198793 PMC11939912__F2 Phytochemicals Targeting BDNF Signaling for Treating Neurological Disorders ENSG00000169291 ENSG00000002330 ENSG00000163914 PMC11939912__F3 ProBDNF/p75NTR reverses the effects of BDNF/TrkB signaling, which activates the mTOR pathway to control actin remodeling and spine protein production, hence weakening dendritic spines [115] ENSG00000198793 PMC3077082__F6 Microbial manipulation of receptor crosstalk in innate immunity ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC12000012__F3 Divergent regulatory pathways in moderate erythropoiesis and excessive erythrocytosis ENSG00000187266 ENSG00000026103 PMC3077082__F4 Microbial manipulation of receptor crosstalk in innate immunity ENSG00000174125 PMC12000012__F5 Pathogenetic cascade of HAPC ENSG00000102145 ENSG00000079387 ENSG00000026103 PMC3077082__F3 Microbial manipulation of receptor crosstalk in innate immunity ENSG00000136869 ENSG00000121966 PMC12000012__F4 Hypoxia-regulated iron homeostasis and erythropoiesis ENSG00000106327 ENSG00000178752 ENSG00000158578 ENSG00000187266 PMC3077082__F2 Microbial manipulation of receptor crosstalk in innate immunity ENSG00000172936 ENSG00000258227 PMC3077082__F1 Microbial manipulation of receptor crosstalk in innate immunity PMC10723408__F1 Workflow and methodology used in this work ENSG00000205221 ENSG00000122966 ENSG00000102119 PMC7835030__F7 NLRC4 gene regulates inflammatory reaction and immune response of DCs in septic shock by mediating the NLR pathway ENSG00000167207 ENSG00000125538 ENSG00000091106 ENSG00000106100 PMC8057295__F1 SHH pathway in the (A) absence or (B) presence of the SHH ligand ENSG00000143147 ENSG00000106571 ENSG00000164161 ENSG00000166813 ENSG00000198742 ENSG00000121067 ENSG00000164690 ENSG00000128602 PMC3852078__F6 BDNF-related PPI network ENSG00000150991 ENSG00000107105 ENSG00000066044 PMC8057295__F2 Schematic presentation of upstream regulation of the SHH signaling pathway and its associations with other cancer-related cellular pathways ENSG00000043355 ENSG00000134371 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000133740 ENSG00000164690 ENSG00000069667 PMC8144890__F3 Energy metabolism disorders and potential therapeutic drugs in heart failure ENSG00000180210 ENSG00000145979 PMC8057295__F4 Models of the SHH signaling pathway in cancer ENSG00000164690 ENSG00000128602 PMC9573421__F5 Phytochemicals in Skeletal Muscle Health: Effects of Curcumin (from Curcuma longa Linn) and Sulforaphane (from Brassicaceae) on Muscle Function, Recovery and Therapy of Muscle Atrophy ENSG00000100387 ENSG00000125538 ENSG00000079999 PMC7508496__F2 BMP 7/Signaling Antagonizes TGFB−Induced Organ Fibrosis: MechanismBMP-7 and TGFB1 bind to distinct type II receptors that form complexes of specific type I serine-threonine kinase receptors ENSG00000170365 PMC3976861__F2 Representation of the p53 signaling pathway map from KEGG ENSG00000149311 ENSG00000132341 PMC4442748__F1 M1 and M2 Immune Activation in Parkinson’s Disease: Foe and Ally? ENSG00000105397 ENSG00000125538 ENSG00000118520 ENSG00000105639 ENSG00000168610 PMC6275025__F1 Insulin signalling pathway ENSG00000169047 ENSG00000133124 PMC5302945__F3 Seven protective miRNA signatures for prognosis of cervical cancer ENSG00000117713 ENSG00000149311 ENSG00000125398 ENSG00000214513 ENSG00000074181 ENSG00000136997 ENSG00000074266 ENSG00000112715 ENSG00000178691 ENSG00000073756 ENSG00000253729 PMC2593123__F1 A simplified schematic of the core left-right signaling pathway in the e8.5 (6 somite) mouse embryo ENSG00000143768 ENSG00000243709 ENSG00000156574 PMC6981493__F5 Representation of the cellular response after insulin stimulation ENSG00000002330 PMC7443512__F5 Unpuzzling COVID-19: tissue-related signaling pathways associated with SARS-CoV-2 infection and transmission ENSG00000130234 ENSG00000184012 PMC8719288__F1 Building Resilience with Aerobic Exercise: Role of FKBP5 ENSG00000145321 PMC5456285__F6 HCoVs on ER stress response ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC9929940__F5 Nanocell COVID-19 vaccine triggers a novel immune response pathway producing high-affinity antibodies which neutralize all variants of concern ENSG00000158473 ENSG00000111537 ENSG00000186716 ENSG00000102970 ENSG00000126353 PMC5456285__F5 HCoV viral proteins on innate immunity ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000125347 PMC6900528__F6 The proposed pathway of IPs synthesis ENSG00000274958 ENSG00000151151 PMC7443512__F2 Unpuzzling COVID-19: tissue-related signaling pathways associated with SARS-CoV-2 infection and transmission ENSG00000162711 ENSG00000125538 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC8849228__F8 Transcriptome Profiling During Muscadine Berry Development Reveals the Dynamic of Polyphenols Metabolism ENSG00000183978 ENSG00000039537 ENSG00000120438 ENSG00000062485 ENSG00000084774 PMC10433440__F6 (A and B) Illustration of classical and non-classical Wnt/Beta-catenin signaling pathways ENSG00000134982 ENSG00000168036 PMC6882007__F1 Hh signaling pathway transduction ENSG00000166813 ENSG00000128602 PMC2814417__F7 The postulated signaling of MAP kinase pathway in proliferating or differentiating HL60 cells ENSG00000170458 ENSG00000141068 PMC5342665__F1 Steps in the LDLR metabolic pathway ENSG00000130164 ENSG00000169174 PMC7287178__F2 Proposed model of the cardiac sarcostat ENSG00000164879 ENSG00000188554 ENSG00000152137 ENSG00000151929 PMC4982475__F6 Simvastatin and dLGG mediate formation of oxylipin mediators by regulation of MAPK-induced cPLA2 activation and downstream signaling cascades ENSG00000226275 PMC3841149__F9 WNT3 Inhibits Cerebellar Granule Neuron Progenitor Proliferation and Medulloblastoma Formation via MAPK Activation ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000164690 ENSG00000128602 ENSG00000277641 PMC9090832__F7 Olig2-Ddx20 axis-mediated suppression of p53 pathway ENSG00000142252 ENSG00000152147 ENSG00000046647 ENSG00000092208 ENSG00000205927 PMC7797087__F1 Schematic model illustrating the cross-talk between the ET-1R axis and the YAP pathway ENSG00000291971 PMC6881651__F10 The Action circTTN Competitively Sponging miR-432 Mediating Myoblast Proliferation and Differentiation ENSG00000111049 ENSG00000122180 ENSG00000132646 ENSG00000123374 ENSG00000129152 PMC7764760__F2 An EGFR-centric view of EV biogenesis ENSG00000138798 ENSG00000146648 PMC11352233__F7 HER2/epidermal growth factor receptor (EGFR) signalling pathway in breast cancer ENSG00000146648 PMC7764760__F3 Pathway diagram of EGFR post-endocytic fate ENSG00000129219 ENSG00000163235 ENSG00000138798 ENSG00000163914 ENSG00000074319 ENSG00000165527 ENSG00000146648 PMC5954861__F3 TBP-2 snd p38 MAPK-NFKB signaling pathway ENSG00000123240 ENSG00000127948 PMC12110717__F2 Schematic view of membrane channels, Ca2+ and inorganic phosphate (Pi) ion trafficking and amorphous calcium phosphate (ACP)/HA formation ENSG00000154143 ENSG00000143183 PMC7768823__F1 Actionable nodes of the autophagy pathway ENSG00000177169 ENSG00000152348 ENSG00000110497 ENSG00000123395 ENSG00000083290 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC5954861__F6 TBP-2 regulates autophagy and apoptosis of HLECs under oxidative stress ENSG00000198793 ENSG00000164305 PMC10917928__F2 TCM polysaccharides’ role in regulating tumor adaptive immune response ENSG00000186716 ENSG00000111837 PMC10917928__F1 TCM polysaccharides’ role in regulating tumor innate immune response ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC5068743__F5 Muscadine Grape Skin Extract Induces an Unfolded Protein Response-Mediated Autophagy in Prostate Cancer Cells: A TMT-Based Quantitative Proteomic Analysis ENSG00000086205 ENSG00000147649 ENSG00000128272 ENSG00000104517 ENSG00000084652 ENSG00000168615 ENSG00000175073 ENSG00000277276 ENSG00000175216 ENSG00000284868 PMC4409326__F2 MicroRNAs in the pathogenesis of cystic kidney disease ENSG00000128191 ENSG00000113360 PMC8599717__F2 Emerging Roles of N6-Methyladenosine (m6A) Epitranscriptomics in Toxicology ENSG00000149658 ENSG00000198492 ENSG00000114127 ENSG00000146457 ENSG00000165819 PMC8289871__F10 Cartoon depicting the putative molecular mechanism for insulin protection of pancreatic acinar cells during acute pancreatitis ENSG00000180210 ENSG00000196839 PMC11040167__F6 Nrf2/ARE pathway as a potential target to ameliorate atrazine-induced endocrine disruption in granulosa cells ENSG00000175054 ENSG00000178573 ENSG00000079999 PMC10140937__F4 Mitochondrial DNA Supplementation of Oocytes Has Downstream Effects on the Transcriptional Profiles of Sus scrofa Adult Tissues with High mtDNA Copy Number ENSG00000143252 ENSG00000151376 ENSG00000179344 ENSG00000277263 ENSG00000131323 ENSG00000105953 ENSG00000112186 ENSG00000172340 ENSG00000146701 ENSG00000082212 ENSG00000091140 ENSG00000062485 PMC7103059__F3 Signaling pathways in osteoclast activation ENSG00000291971 ENSG00000100985 ENSG00000175104 ENSG00000127191 PMC3585436__F3 p110D PI3K pathway in B cells ENSG00000177455 ENSG00000170458 ENSG00000186716 ENSG00000197943 ENSG00000113520 ENSG00000136869 ENSG00000010671 PMC3585436__F2 Simplified scheme showing the critical role of Class IA PI3Ks in multiple cellular functions ENSG00000002330 PMC3585436__F4 p110D PI3K mediates the effects of CSF-1 or EGF via RhoA and PTEN in macrophages and some solid tumor cells ENSG00000291971 ENSG00000138798 PMC3680388__F5 Novel Strategy to Increase the Proliferative Potential of Adult Human Beta-Cells While Maintaining Their Differentiated Phenotype ENSG00000180245 ENSG00000154342 ENSG00000162337 ENSG00000275190 ENSG00000020633 ENSG00000104332 ENSG00000277641 ENSG00000168610 ENSG00000196628 ENSG00000140807 ENSG00000111962 ENSG00000271271 ENSG00000065328 ENSG00000138336 ENSG00000105397 ENSG00000119655 ENSG00000134853 ENSG00000161202 ENSG00000155760 ENSG00000175792 PMC5608693__F6 Model of step-wise progression in DPN-like melanoma ENSG00000117713 ENSG00000157764 ENSG00000134982 ENSG00000164362 ENSG00000168036 PMC2727867__F1 Representation of some zinc-induced apoptotic pathways ENSG00000180210 ENSG00000117525 ENSG00000166278 PMC6007054__F8 Diagram showing effects of 4-HNE on Keap1- and GSK3Beta-mediated Nrf2 degradation ENSG00000079999 PMC10976824__F2 Infection of endothelial cells by pathogenic microorganisms triggers the activation of the NFKB pathway, resulting in increased levels of HIF-1A ENSG00000174125 ENSG00000088888 ENSG00000187796 ENSG00000137275 ENSG00000102871 ENSG00000291971 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000127191 PMC3926505__F3 Roles of Cu in synaptic function ENSG00000177556 PMC3926505__F1 Key organelles and proteins involved in cellular Cu homeostasis ENSG00000142192 ENSG00000173992 ENSG00000138495 ENSG00000177556 PMC5819894__F11 Metabolic enzymes targeted by p53 ENSG00000284194 ENSG00000159399 PMC4414174__F9 Cytoplasmic TRAF4 contributes to the activation of p70s6k signaling pathway in breast cancer ENSG00000198793 ENSG00000127191 ENSG00000076604 PMC6963500__F9 Activation of the Wnt/Fz ligand-receptor leads to the production of the second messengers IP3 and DAG from membrane-bound PIP2 via the action of membrane-bound enzyme PLC ENSG00000036828 PMC9420645__F1 Toll-Like Receptor 4: A Promising Therapeutic Target for Alzheimer's Disease ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 PMC4831844__F2 Computational Reconstruction of NFKB Pathway Interaction Mechanisms during Prostate Cancer ENSG00000160888 ENSG00000124216 ENSG00000135604 ENSG00000109321 ENSG00000163734 ENSG00000173039 ENSG00000128342 ENSG00000163661 ENSG00000125347 ENSG00000073756 ENSG00000166592 PMC8817839__F2 CGRP: A New Endogenous Cell Stemness Maintenance Molecule ENSG00000161798 ENSG00000164690 ENSG00000196689 PMC7746538__F2 Cathepsins in macrophage functions during bacterial infection ENSG00000162711 ENSG00000102189 ENSG00000163131 ENSG00000005893 ENSG00000172936 ENSG00000164342 ENSG00000143387 PMC4922528__F2 TLR and NLR signaling ENSG00000174125 ENSG00000162711 ENSG00000170458 ENSG00000187554 ENSG00000125538 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC3827948__F6 S4 controls FGF2-mediated signaling through RhoG-dependent macropinocytosis of the FGFR1-S4-FGF2 signaling complex ENSG00000077782 PMC9604716__F3 LL-37 in Bone and Periodontium Regeneration ENSG00000171049 ENSG00000136869 ENSG00000146648 ENSG00000140443 PMC8386479__F7 Cysteine Boosts Fitness Under Hypoxia-Mimicked Conditions in Ovarian Cancer by Metabolic Reprogramming PMC12044029__F6 Bone-derived factors regulate renal functions ENSG00000111012 ENSG00000118972 ENSG00000148346 ENSG00000167941 ENSG00000118515 PMC6305653__F2 Signaling pathway analysis of KEGG and PANTHER pathways shows that the miR‐34a/BCL‐2 axis is mostly involved in apoptotic pathways ENSG00000132906 ENSG00000002330 ENSG00000102871 ENSG00000138794 ENSG00000164399 ENSG00000168040 ENSG00000127191 ENSG00000164305 ENSG00000149311 ENSG00000291983 ENSG00000172936 ENSG00000064012 ENSG00000026103 PMC9656419__F3 Intestinal Flora Derived Metabolites Affect the Occurrence and Development of Cardiovascular Disease ENSG00000115415 ENSG00000136997 ENSG00000168610 PMC8377544__F5 Physiological Signaling Functions of Reactive Oxygen Species in Stem Cells: From Flies to Man ENSG00000086991 ENSG00000175567 ENSG00000096717 PMC9257083__F6 Gut Microbiota-Derived Diaminopimelic Acid Promotes the NOD1/RIP2 Signaling Pathway and Plays a Key Role in the Progression of Severe Acute Pancreatitis ENSG00000112977 ENSG00000106100 PMC8377544__F4 Physiological Signaling Functions of Reactive Oxygen Species in Stem Cells: From Flies to Man ENSG00000133937 ENSG00000146648 PMC2917144__F1 Toll-like receptor signaling pathway ENSG00000183735 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC3772104__F2 Involvement of the JAK-STAT signaling pathway in chronic inflammatory skin disease atopic dermatitis ENSG00000006606 ENSG00000142224 ENSG00000106178 PMC3772104__F1 The involvement of the JAK-STAT signaling pathway in chronic inflammatory skin disease atopic dermatitis ENSG00000203782 ENSG00000107485 ENSG00000049768 ENSG00000105639 PMC6947643__F2 The gamma secretase (Gamma-secretase) complex: It is comprised of presenilin enhancer (PEN-2), anterior pharynx-defective 1 (APH1) and nicastrin ENSG00000114315 ENSG00000137845 PMC11734646__F9 SCF involves in the regulation of immune response ENSG00000008710 ENSG00000110429 ENSG00000160224 ENSG00000099364 ENSG00000072803 PMC5802154__F8 Intracellular signaling mechanisms that induce epithelial mesenchymal transition during CSE-induced aberrant EGFR activation in human RPE cells ENSG00000197713 ENSG00000105329 ENSG00000291971 PMC8286839__F8A Figure 8.NFKB dependent inhibitory feedback at the receptor level ENSG00000170458 ENSG00000136869 PMC2610366__F1 Pathways involved in folate-dependent methionine transmethylation and transsulfuration PMC4945639__F2 WNT/Beta-catenin signaling pathway in adrenal tumorigenesis ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000183579 ENSG00000168036 PMC9313047__F3 Pathological Features and Neuroinflammatory Mechanisms of SARS-CoV-2 in the Brain and Potential Therapeutic Approaches ENSG00000108691 ENSG00000130234 ENSG00000277943 ENSG00000164342 PMC7281661__F6 LAB-mediated modulation of inflammatory responses in bovine mammary epithelial (BME) cells ENSG00000115008 ENSG00000081041 ENSG00000163734 ENSG00000172936 ENSG00000136869 ENSG00000185187 PMC4298363__F7 Suppression of ghrelin signaling mitigates age-associated thermogenic impairment ENSG00000116688 ENSG00000169047 ENSG00000121853 PMC6835776__F3 Proposed effects of ZnO nanocomposites on antigen-presenting cells and their potential role in inducing T cell responses in draining lymph node ENSG00000111537 ENSG00000214285 ENSG00000172936 PMC8529605__F5 Mechanisms and Molecular Targets of Compound Danshen Dropping Pill for Heart Disease Caused by High Altitude Based on Network Pharmacology and Molecular Docking ENSG00000134086 ENSG00000173156 ENSG00000127948 ENSG00000280548 ENSG00000101425 PMC7504796__F3 Interdependence of CAT:MST axis, glutathione (GSH) bioavailability and cysteine metabolism PMC7504796__F1 Role of the glutamate oxaloacetate transaminases: 3-mercaptopyruvate sulfurtransferase (CAT:MST) axis in promoting and sustaining cancer ENSG00000100294 ENSG00000079999 PMC9340905__F1 Next-generation selective estrogen receptor degraders and other novel endocrine therapies for management of metastatic hormone receptor-positive breast cancer: current and emerging role ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000146648 PMC9409144__F1 Oxidised Low-Density Lipoprotein-Induced Platelet Hyperactivity—Receptors and Signalling Mechanisms ENSG00000135218 ENSG00000010810 ENSG00000172572 ENSG00000132478 ENSG00000172936 ENSG00000184216 ENSG00000213523 PMC3123543__F4 Overlaid networks predicted by the PLS method and generated by IPA pathway designer ENSG00000167470 ENSG00000124882 PMC1297640__F1 Systems and molecular complexity in glycobiology ENSG00000159921 ENSG00000069482 ENSG00000198380 ENSG00000254685 ENSG00000124357 ENSG00000174059 ENSG00000174611 PMC9262756__F2 Aberrant expression of miRNAs in epilepsy ENSG00000128917 ENSG00000148400 ENSG00000134982 ENSG00000074181 ENSG00000273529 ENSG00000114315 ENSG00000137845 ENSG00000090932 PMC3233204__F4 DEVELOMENT AND NEUROGENIC POTENTIAL OF MÜLLER GLIAL CELLS IN THE VERTEBRATE RETINA ENSG00000112576 ENSG00000134438 ENSG00000138798 PMC6457004__F5 Schematic model in which HMW FGF2-mediated FGF23 stimulation of chondrocyte differentiation and OA is partially through modulation of the Wnt/Beta-catenin pathway ENSG00000118972 ENSG00000154736 ENSG00000167941 ENSG00000188064 ENSG00000168036 ENSG00000168646 PMC6103261__F1 Comprehensive high-resolution multiple-reaction monitoring mass spectrometry for targeted eicosanoid assays ENSG00000226275 ENSG00000173599 PMC5921900__F2 Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges ENSG00000102962 ENSG00000151882 ENSG00000108691 ENSG00000107562 ENSG00000102970 ENSG00000184371 PMC4110655__F2 Proposed mechanism of action of the erythroid regulator ERFE ENSG00000178752 PMC8064803__F2 Neuroinflammatory Mechanisms of Mitochondrial Dysfunction and Neurodegeneration in Glaucoma ENSG00000162711 ENSG00000172936 ENSG00000136869 ENSG00000166278 ENSG00000182326 PMC8300636__F1 Relevance of Plant-Derived Se Compounds to Human Health in the SARS-CoV-2 (COVID-19) Pandemic Era ENSG00000110395 ENSG00000179988 ENSG00000062485 PMC8783100__AF1 Secretory pathway Ca2+-ATPase SPCA2 regulates mitochondrial respiration and DNA damage response through store-independent calcium entry ENSG00000149311 ENSG00000175054 ENSG00000293604 PMC5161753__F5 Summary of the mechanisms for LAPTM4B promoting cancer development ENSG00000132906 ENSG00000087245 ENSG00000138798 ENSG00000100744 ENSG00000100985 ENSG00000104341 ENSG00000184481 ENSG00000146648 PMC7677142__F1 Subcellular localization of the cholesterol biosynthetic pathway in mammalian cells ENSG00000276559 ENSG00000186480 PMC9279817__F7 MiR-20a: a mechanosensitive microRNA that regulates fluid shear stress-mediated osteogenic differentiation via the BMP2 signaling pathway by targeting BAMBI and SMAD6 ENSG00000170365 ENSG00000137834 ENSG00000291837 PMC10963404__F6 Mode of action of DMXAA and its derivative HHMX in human and mice ENSG00000183735 ENSG00000164430 PMC5732764__F1 Dietary folate levels alter the kinetics and molecular mechanism of prostate cancer recurrence in the CWR22 model ENSG00000088826 ENSG00000148832 ENSG00000099810 ENSG00000123505 ENSG00000116649 ENSG00000102172 PMC2757227__F1 Regulation of ENaC and CFTR by SGK1/Nedd4-2 ENSG00000005882 ENSG00000118515 ENSG00000001626 PMC7319342__F7 ROS regulation of RAS and vulva development in Caenorhabditis elegans ENSG00000140279 PMC8167992__SF1 Targetable nanoparticle BAF312@cRGD-CaP-NP represses tumor growth and angiogenesis by downregulating the S1PR1/P-STAT3/VEGFA axis in triple-negative breast cancer ENSG00000170989 ENSG00000112715 ENSG00000168610 PMC8476858__F1 Editorial: Intracellular Mechanisms of Alpha-Synuclein Processing ENSG00000159335 PMC7468876__F2 Schematic representation in IPA of the ILK signalling pathway ENSG00000196531 ENSG00000111057 ENSG00000138795 ENSG00000198793 ENSG00000177606 ENSG00000164327 ENSG00000071051 ENSG00000132478 ENSG00000100985 ENSG00000164305 ENSG00000089159 PMC9377691__F3 Supramolecular organizing centers at the interface of inflammation and neurodegeneration ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000131323 ENSG00000175104 PMC5031543__F3 HGF signaling pathways; A) Representative structures, cMET binding affinities (KD) and dimerization of HGF, NK1 (cMET agonists) and NK2 (cMET antagonists ENSG00000019991 PMC5812256__F1 Bile Acids in Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis ENSG00000160867 ENSG00000276559 ENSG00000180432 ENSG00000135929 PMC7242157__F1 Metabolic, renal and neural health are impacted by a ketogenic diet ENSG00000162711 ENSG00000105550 ENSG00000130234 ENSG00000198793 ENSG00000060566 PMC7932549__F2 Overexpression of DNA repair genes in invasive ductal and lobular breast carcinomas: Insights on individual variations and precision medicine ENSG00000187608 ENSG00000039650 ENSG00000163918 ENSG00000115350 ENSG00000035928 ENSG00000183765 ENSG00000105486 ENSG00000104320 ENSG00000116030 ENSG00000164053 ENSG00000197774 ENSG00000187790 ENSG00000115392 ENSG00000187741 ENSG00000112039 ENSG00000158169 ENSG00000111602 ENSG00000100387 ENSG00000143476 ENSG00000132646 ENSG00000122008 ENSG00000182481 ENSG00000154920 ENSG00000188827 ENSG00000165280 ENSG00000175279 ENSG00000175054 ENSG00000169689 ENSG00000150991 ENSG00000132604 ENSG00000158019 ENSG00000109685 ENSG00000132383 ENSG00000064655 ENSG00000139372 ENSG00000129071 ENSG00000177084 ENSG00000106628 ENSG00000166803 ENSG00000185515 ENSG00000130997 ENSG00000092330 ENSG00000102977 ENSG00000131944 ENSG00000149311 ENSG00000197299 ENSG00000133119 ENSG00000227345 ENSG00000182179 PMC4650856__F4 Wnt signaling pathway involved in SPN ENSG00000138795 ENSG00000242110 ENSG00000198561 ENSG00000168036 PMC7985179__F2 Key proteins and interactions in coronavirus disease-related pulmonary fibrosis (COVID-PF) ENSG00000070193 ENSG00000140564 ENSG00000167207 ENSG00000105329 ENSG00000030304 ENSG00000113161 ENSG00000120885 ENSG00000112715 ENSG00000163631 ENSG00000213030 ENSG00000130234 ENSG00000125538 ENSG00000090376 ENSG00000142192 ENSG00000125817 ENSG00000115163 ENSG00000197635 ENSG00000164761 ENSG00000129226 ENSG00000169919 ENSG00000163661 ENSG00000132170 ENSG00000066468 ENSG00000156970 ENSG00000124882 ENSG00000102245 ENSG00000184371 PMC6079124__F1 Several Proposed important schematic signaling pathways for Gankyrin in tumorigenesis ENSG00000125538 ENSG00000173039 ENSG00000168036 ENSG00000168610 ENSG00000184216 PMC6643872__F2 ETC and ATP synthase are required for normal eye development ENSG00000073578 ENSG00000130414 ENSG00000131495 ENSG00000117118 ENSG00000166260 ENSG00000166136 ENSG00000147123 ENSG00000006695 ENSG00000139180 ENSG00000128609 ENSG00000184752 ENSG00000110717 ENSG00000147684 ENSG00000184983 ENSG00000138495 ENSG00000292058 ENSG00000004779 ENSG00000165264 ENSG00000178127 ENSG00000143252 ENSG00000267855 ENSG00000183648 ENSG00000136521 ENSG00000127184 ENSG00000213619 ENSG00000065518 ENSG00000151366 ENSG00000186010 ENSG00000189043 ENSG00000099795 ENSG00000119013 PMC8931059__F3 CD95-dependent non-apoptotic signaling ENSG00000293604 ENSG00000198793 ENSG00000124181 PMC8931059__F2 CD95-dependent apoptotic signaling ENSG00000168040 ENSG00000164305 PMC11643440__F2 Insulin signaling pathway in adipocytes in healthy and obese (pathologic) subjects ENSG00000117525 ENSG00000150907 PMC12090549__F5 For combining inhibition of the adenosinergic pathway and other cancer immunotherapies ENSG00000134982 ENSG00000196839 PMC8143539__F3 Using Pharmacogenetics of Direct Oral Anticoagulants to Predict Changes in Their Pharmacokinetics and the Risk of Adverse Drug Reactions ENSG00000262243 PMC12090549__F4 Immunosuppressive effects of adenosine within the tumor microenvironment ENSG00000107562 PMC7656123__F3 Identification of an important regulatory role for miR-574-3p-mediated signaling pathways (especially the EGFR/RAC1 pathway) in spinal chordoma by integrated analysis of both the miRNA-mRNA and protein-protein interaction networks data ENSG00000069869 ENSG00000133606 ENSG00000182585 ENSG00000113070 ENSG00000106299 ENSG00000165376 ENSG00000175591 ENSG00000137265 ENSG00000137845 ENSG00000146648 ENSG00000141367 PMC12090549__F1 Adenosine production and signaling pathway ENSG00000196839 ENSG00000291814 PMC7998716__F1 Activation of Tyro3, Axl and MerTK (TAM) receptors on cancer cells results in downstream oncogenic signaling ENSG00000167601 ENSG00000153208 ENSG00000092445 ENSG00000006451 ENSG00000144118 ENSG00000163914 ENSG00000100985 PMC8024568__F1 IL-10, 13, 17, and 33 interaction mechanism with their specific receptors ENSG00000105397 ENSG00000137033 ENSG00000172936 ENSG00000175104 ENSG00000168610 PMC10459248__F2 Cellular pathways modulated by ASFV ENSG00000182481 ENSG00000177575 ENSG00000177169 ENSG00000132109 ENSG00000162711 ENSG00000159128 ENSG00000213928 ENSG00000102753 ENSG00000185436 ENSG00000141458 ENSG00000027697 ENSG00000168610 ENSG00000276561 ENSG00000142166 ENSG00000116815 ENSG00000158473 ENSG00000164430 ENSG00000166887 ENSG00000105397 ENSG00000115415 ENSG00000005893 ENSG00000243646 ENSG00000186432 ENSG00000292357 PMC11890030__F1 Comprehensive strategies for paclitaxel production: insights from plant cell culture, endophytic microorganisms, and synthetic biology ENSG00000197429 PMC11890030__F3 Comprehensive strategies for paclitaxel production: insights from plant cell culture, endophytic microorganisms, and synthetic biology ENSG00000105722 ENSG00000136997 ENSG00000197429 PMC9633854__F3 Choroid plexus epithelium and its role in neurological diseases ENSG00000111537 PMC4451983__F2 Functions of lncRNAs in autoimmune cells, T cells, B cells, macrophages, NK, and dendritic cells ENSG00000111537 ENSG00000168610 ENSG00000196363 PMC5035020__F4 Transcriptomic Study on Ovine Immune Responses to Fasciola hepatica Infection ENSG00000157933 ENSG00000146872 ENSG00000133937 ENSG00000235376 ENSG00000156574 PMC5356817__F5 Aberrant expression of lncRNAs and mRNAs in patients with intracranial aneurysm ENSG00000112799 ENSG00000174125 ENSG00000051523 ENSG00000283934 ENSG00000067900 ENSG00000043462 ENSG00000159189 ENSG00000101605 ENSG00000109861 ENSG00000072694 ENSG00000170458 ENSG00000130775 ENSG00000185532 ENSG00000163017 ENSG00000120729 PMC7350910__F4 Crosstalk between the TNF-related pathway and CS response ENSG00000104689 ENSG00000145321 ENSG00000168040 PMC5074868__F8 MYELOID HSF1-Beta-CATENIN AXIS REGULATES NLRP3 INFLAMMASOME ACTIVATION IN MOUSE LIVER ISCHEMIA/REPERFUSION INJURY ENSG00000162711 ENSG00000284774 ENSG00000125538 ENSG00000168036 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC9359082__F2 CMTM6 and CMTM4 as two novel regulators of PD-L1 modulate the tumor microenvironment ENSG00000091317 ENSG00000125285 ENSG00000183723 ENSG00000198793 ENSG00000168036 PMC6771392__F7 Model of HROB function in homologous recombination ENSG00000125319 ENSG00000163312 ENSG00000051180 PMC8268587__F1 Osteoblast Differentiation and Signaling: Established Concepts and Emerging Topics ENSG00000150938 ENSG00000170365 ENSG00000137834 ENSG00000281324 ENSG00000162337 ENSG00000095739 ENSG00000134982 ENSG00000168036 PMC4714567__F6 Ah Receptor Pathway Intricacies; Signaling Through Diverse Protein Partners and DNA-Motifs ENSG00000123374 ENSG00000140465 ENSG00000106546 PMC4714567__F5 Ah Receptor Pathway Intricacies; Signaling Through Diverse Protein Partners and DNA-Motifs ENSG00000106546 PMC3530773__F3 Vasopressin signaling network ENSG00000005981 ENSG00000143514 ENSG00000002330 ENSG00000141503 ENSG00000102893 ENSG00000196218 ENSG00000087460 PMC4714567__F3 Ah Receptor Pathway Intricacies ENSG00000178573 ENSG00000173039 ENSG00000140465 ENSG00000106546 PMC7864232__F7 Diversity and Biology of Cancer-Associated Fibroblasts ENSG00000164690 ENSG00000128602 PMC4714567__F2 Ah Receptor Pathway Intricacies; Signaling Through Diverse Protein Partners and DNA-Motifs ENSG00000005421 ENSG00000106546 PMC7519530__F6 Hypothesized role of miR-142-5p and miR-365a-3p in CML signaling ENSG00000132906 ENSG00000002330 ENSG00000075142 ENSG00000198793 ENSG00000143322 PMC11918467__F6 H2 can protect H9c2 cells from H/R injury by inhibiting the Wnt/CX3CR1 signaling pathway ENSG00000168329 ENSG00000134982 ENSG00000168036 ENSG00000189403 ENSG00000136869 PMC8267696__F1 Metabolic Reprogramming: A Friend or Foe to Cancer Therapy? ENSG00000120868 ENSG00000168040 ENSG00000026103 PMC8869954__F1 RAF Kinase Inhibitor Protein (RKIP): Good as Tumour Suppressor, Bad for the Heart ENSG00000148400 ENSG00000291971 ENSG00000136997 ENSG00000168610 PMC5332476__F1 The role of Rho GTPase/Rho kinase signaling pathway in regulation of actin cytoskeletal organization and cellular processes in smooth muscle and non-smooth muscle cells ENSG00000163914 ENSG00000198670 PMC5332476__F2 Inhibitors of Rho GTPase and Rho kinase lower IOP by increasing aqueous humor outflow through the conventional pathway and exhibit neuroprotective effects by stimulating axonal outgrowth and retinal ganglion cell survival ENSG00000163914 PMC9180238__F1 MicroRNA-202 as a Diagnostic Biomarker and a Potential Tumor Suppressor ENSG00000147649 ENSG00000198793 ENSG00000189299 PMC6797603__F1 NLRX1 regulates immune system signaling ENSG00000162711 ENSG00000088888 ENSG00000140740 ENSG00000160703 PMC4857091__F6 Evaluation of energy metabolism and calcium homeostasis in cells affected by Shwachman-Diamond syndrome ENSG00000198793 ENSG00000242372 PMC9433407__F9 Suppression of PFKFB3-driven glycolysis restrains endothelial-to-mesenchymal transition and fibrotic response ENSG00000180210 ENSG00000182511 PMC6235699__F2 NAD+ and sirtuins in retinal degenerative diseases: a look at future therapies ENSG00000105835 ENSG00000157064 ENSG00000173614 PMC7323198__F2 Schematic summary of SARS‐CoV‐2 entry into host cells, replication, effect on host cells, and postulated effects of statins ENSG00000145604 ENSG00000162711 ENSG00000130234 ENSG00000125538 PMC5578165__F1 The Retinoblastoma (RB) Tumor Suppressor: Pushing Back against Genome Instability on Multiple Fronts ENSG00000149311 ENSG00000012048 ENSG00000051180 ENSG00000139618 PMC5645057__F1 TGFB signaling pathway in prostate cancer cells ENSG00000137834 PMC4100143__F1 Diagram of CD4 T cell differentiation and immunomodulation by the AhR signaling pathway ENSG00000115415 ENSG00000113520 ENSG00000107485 ENSG00000049768 ENSG00000106546 PMC8458263__F2 RSR blockade stimulates innate anti-tumor immunity through the cGAS-STING pathway ENSG00000169245 ENSG00000183735 ENSG00000111537 PMC4794670__F4 Network of type I interferon response- and UPR-related genes ENSG00000125740 ENSG00000187608 ENSG00000105516 ENSG00000185745 ENSG00000221869 ENSG00000162772 ENSG00000070669 ENSG00000172183 ENSG00000123685 ENSG00000245848 ENSG00000172216 ENSG00000101255 ENSG00000156127 ENSG00000108924 ENSG00000146592 ENSG00000153879 ENSG00000177606 ENSG00000123609 ENSG00000170653 ENSG00000092067 PMC6534082__F1 The mutIDH1 and mutIDH2 pathways and molecular mechanisms related to oncogenesis ENSG00000151376 ENSG00000138336 ENSG00000106397 ENSG00000083444 ENSG00000152952 PMC7507458__F3 Links between lncRNAs and Hippo signalling cascade ENSG00000163993 ENSG00000159399 PMC8603304__F1 Fungal cell wall components modulate our immune system ENSG00000162711 ENSG00000125538 ENSG00000198793 ENSG00000136869 PMC7507458__F2 Links between lncRNAs and Hippo signalling cascade ENSG00000068028 ENSG00000142731 ENSG00000253352 ENSG00000131023 PMC9264363__F7 Mitochondrial antiviral-signalling protein is a client of the BAG6 protein quality control complex ENSG00000088888 ENSG00000104969 ENSG00000204463 ENSG00000105726 ENSG00000102178 PMC7507458__F4 Reciprocal interaction between lncRNAs and Hippo cascade ENSG00000126016 ENSG00000150457 ENSG00000131023 PMC7879558__F1 NHEJ and antiviral innate immunity ENSG00000183735 ENSG00000276561 PMC1705513__F1 Inflammatory pathway in psoriasis ENSG00000163235 ENSG00000137077 ENSG00000184451 ENSG00000126353 ENSG00000112149 ENSG00000174059 ENSG00000162692 ENSG00000277943 ENSG00000115009 ENSG00000112486 PMC8202900__F7 Acetyl oxygen benzoate engeletin ester promotes KLF4 degradation leading to the attenuation of pulmonary fibrosis via inhibiting TGFB1–smad/p38MAPK–lnc865/lnc556–miR-29b-2-5p–STAT3 signal pathway ENSG00000105329 ENSG00000168610 ENSG00000136826 PMC8807838__F9 Promotion of the inflammatory response in mid colon of complement component 3 knockout mice ENSG00000162711 ENSG00000091138 ENSG00000001626 PMC7507458__F1 Molecular schematic of canonical Hippo signalling cascade in cancers ENSG00000150457 ENSG00000131023 PMC2168916__F7 Regulation of the AHR-XRE pathway by NRF2 ENSG00000106546 ENSG00000079999 PMC1361361__F7 Shp-1 mediates the anti-proliferative activity of TIMP-2 in human microvascular endothelial cells ENSG00000135446 ENSG00000123374 ENSG00000077782 PMC7267004__F1 Phagocytic receptors and modulating factors functioning in the phagocytosis as well as the antigen-presenting effect to naïve T cells in teleost phagocytic B cells ENSG00000239732 ENSG00000186716 PMC10341927__F10 Identification of Moesin (MSN) as a Potential Therapeutic Target for Colorectal Cancer via the Beta-Catenin-RUNX2 Axis ENSG00000168036 PMC6611515__F4 Comparative RNA-seq analysis reveals dys-regulation of major canonical pathways in ERG-inducible LNCaP cell progression model of prostate cancer ENSG00000135446 ENSG00000115942 ENSG00000135336 ENSG00000080839 ENSG00000093009 PMC9005906__F1 Immunomodulation as a Protective Strategy in Chronic Otitis Media ENSG00000273992 ENSG00000112977 ENSG00000162711 ENSG00000167207 ENSG00000172936 ENSG00000125347 ENSG00000106100 ENSG00000146648 PMC2999475__F8 Summary of metabolomic findings in Hnf1a-null mice ENSG00000135100 ENSG00000171759 PMC3819728__F1 Unfolded protein response and its regulation on cell activities ENSG00000128272 ENSG00000144895 ENSG00000106459 PMC11491690__F1 HOXA9/MEIS1 and FBXO22 promotion of KMT2A‐r acute leukemia ENSG00000118058 ENSG00000078399 ENSG00000168036 ENSG00000143995 ENSG00000156273 PMC4637163__F3 Immunological Basis in the Pathogenesis and Treatment of Bladder Cancer ENSG00000177575 ENSG00000125538 ENSG00000168610 PMC7911109__F1 Oxidative stress and antioxidants in the context of non-alcoholic fatty liver disease (NAFLD) ENSG00000128272 ENSG00000042832 PMC3621409__F5 Evolution of mirrregulation ENSG00000138798 ENSG00000079432 ENSG00000146648 PMC4637163__F2 Immunological Basis in the Pathogenesis and Treatment of Bladder Cancer ENSG00000108691 ENSG00000168610 ENSG00000277943 PMC6172046__F7 Taurine Upregulated Gene 1 signaling circuit in osteosarcoma ENSG00000124102 ENSG00000253352 ENSG00000121879 PMC8898369__F8 TSG-6 promotes Cancer Cell aggressiveness in a CD44-Dependent Manner and Reprograms Normal Fibroblasts to create a Pro-metastatic Microenvironment in Colorectal Cancer ENSG00000026508 ENSG00000146648 PMC6524718__F4 The Nodal signaling cascade ENSG00000143768 ENSG00000156574 ENSG00000164093 ENSG00000130283 PMC3448918__F8 Proposed mechanism for D10G-mediated suppression of NFKB-regulated gene expression ENSG00000187554 ENSG00000136869 PMC5951999__F7 Mechanism underlying how BYD exerts a cardioprotective effect ENSG00000162889 ENSG00000171791 PMC4656338__F2 Signal transduction pathway in HIF-1A regulation ENSG00000134086 ENSG00000198793 PMC8750610__F1 Heat Shock Protein 22 in Physiological and Pathological Hearts: Small Molecule, Large Potentials ENSG00000165280 ENSG00000151929 ENSG00000168610 PMC3571113__F1 Six important signaling networks of osteoblast differentiation ENSG00000196411 ENSG00000128272 ENSG00000162337 ENSG00000134982 ENSG00000167941 PMC5209547__F1 Quantification of thalamocortical dynamics using natural and artificial paired-pulse paradigm ENSG00000167323 ENSG00000109689 PMC5564849__F5 Integration of phytochemicals and phytotherapy into cancer precision medicine ENSG00000161647 ENSG00000105722 ENSG00000164932 ENSG00000096092 ENSG00000115207 ENSG00000169291 ENSG00000198062 ENSG00000178772 ENSG00000113558 ENSG00000170275 ENSG00000156990 ENSG00000197498 ENSG00000174579 ENSG00000064607 ENSG00000167232 ENSG00000119912 ENSG00000139687 ENSG00000091140 ENSG00000152518 ENSG00000125968 ENSG00000122678 PMC8692699__F2 Roles of long non-coding RNAs in lung cancer ENSG00000140992 ENSG00000105991 ENSG00000185591 ENSG00000165462 PMC3925027__F2 Cytokines and their receptors regulating peripheral B-cell survival ENSG00000019582 ENSG00000019991 ENSG00000186716 ENSG00000026508 ENSG00000292210 PMC3130501__F1 Intrinsic and extrinsic apoptotic pathways ENSG00000002330 ENSG00000168040 PMC5803919__F1 Systemic iron homeostasis ENSG00000010704 ENSG00000089472 ENSG00000106327 ENSG00000178752 ENSG00000105697 PMC4262241__F3 Network enrichment analysis of point mutations in genome TCGA-02-0014 ENSG00000119535 ENSG00000197893 ENSG00000050748 ENSG00000164796 ENSG00000133401 ENSG00000169184 ENSG00000166484 ENSG00000141968 ENSG00000139618 ENSG00000061938 ENSG00000183735 ENSG00000134853 ENSG00000131018 ENSG00000155957 ENSG00000151914 ENSG00000146648 ENSG00000253729 ENSG00000105287 PMC11615452__F2 Therapeutic strategies targeting Wnt/Beta-catenin signaling ENSG00000156076 ENSG00000168036 ENSG00000106483 PMC3075376__F1 Targeting GSK-3 family members in the heart: A very sharp double-edged sword ENSG00000162337 ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC11615452__F1 Wnt signaling pathway ENSG00000087095 ENSG00000070831 ENSG00000100592 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC8699097__F1 Therapeutic Targets of KRAS in Colorectal Cancer ENSG00000068028 PMC5070770__F8 Fine-Tuning of the Kaposi’s Sarcoma-Associated Herpesvirus Life Cycle in Neighboring Cells through the RTA-JAG1-Notch Pathway ENSG00000065717 ENSG00000138795 ENSG00000148400 PMC5625838__F2A Innate and Adaptive Immune Responses in Chronic HCV infection ENSG00000183735 ENSG00000088888 ENSG00000102871 ENSG00000082512 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC4799835__F3 TRAF6 in T lymphocyte activation and differentiation ENSG00000198793 ENSG00000107485 ENSG00000049768 ENSG00000175104 PMC10564417__F7 Schematic diagram showing the proposed mechanisms by which exosomal miR-486-5p derived from M2 macrophages regulates the osteogenic and adipogenic differentiation of BMMSCs PMC7175141__F1 Association between IDH1/2 mutation and NAD Production in Cancer ENSG00000228716 ENSG00000105835 ENSG00000278488 ENSG00000008130 PMC10649670__F6 Central illustration ENSG00000165197 ENSG00000259207 ENSG00000183625 ENSG00000113140 ENSG00000137801 ENSG00000128165 ENSG00000169245 ENSG00000186810 ENSG00000108691 ENSG00000100219 ENSG00000171951 ENSG00000163638 ENSG00000106178 PMC8072900__F3 Insulin Resistance in MAFLD ENSG00000042832 ENSG00000169047 PMC7895515__F1 TGFB signaling pathway PMC9490123__F1 DNA damage, inflammation and aging: Insights from mice ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000108582 ENSG00000164430 ENSG00000138385 PMC5751354__F2 Molecular changes driving the Warburg effect ENSG00000074800 ENSG00000198793 PMC5751354__F1 Glucose metabolism in cells PMC8131720__F8 Downregulation of miR-218 by porcine reproductive and respiratory syndrome virus facilitates viral replication via inhibition of type I interferon responses ENSG00000213928 ENSG00000105397 ENSG00000115415 PMC8906930__F4 NRF2 in Bone Metabolism – Friend or Foe? ENSG00000204103 ENSG00000004948 ENSG00000164935 ENSG00000136997 ENSG00000175104 ENSG00000131196 ENSG00000159788 ENSG00000143387 PMC4068281__F3 Signaling pathways and transcription factors supporting or affecting the barrier phenotype of CNS-ECs ENSG00000157554 ENSG00000181019 ENSG00000010810 ENSG00000168036 ENSG00000136352 ENSG00000164690 ENSG00000203883 PMC8906930__F1 NRF2 in Bone Metabolism – Friend or Foe? ENSG00000100387 ENSG00000196839 ENSG00000172005 ENSG00000079999 PMC5777696__F1 S1P/S1P5pathway in mitotic regulation ENSG00000166851 ENSG00000183018 PMC5466503__F4 Melanocyte differentiation ENSG00000138795 ENSG00000157933 ENSG00000135903 ENSG00000080166 ENSG00000100146 PMC9344019__F2 Emerging roles of ER-resident selenoproteins in brain physiology and physiopathology ENSG00000113811 ENSG00000183291 ENSG00000134910 ENSG00000165280 ENSG00000162430 ENSG00000198843 ENSG00000198832 PMC7696189__F7 Tyrosine kinase inhibitor (TKI)-based OFF-switch ENSG00000177455 ENSG00000291603 PMC5466503__F2 Melanocyte activation integrated in the schematic view of the UV-induced pigmentation pathway in the normal skin ENSG00000019991 ENSG00000125398 ENSG00000080166 ENSG00000128342 ENSG00000107165 PMC3227097__F6 Network of core pathways that mediate commitment of cells to the division cycle ENSG00000145604 ENSG00000104365 ENSG00000157933 ENSG00000002330 ENSG00000291971 ENSG00000136997 ENSG00000106299 PMC7447312__F7 Working model ENSG00000138378 PMC6795908__F5 Protein-protein network analysis using the DE genes (log2 fold > 2 and < 2) in the transcriptomic profiles of the cows with PTB-associated lesions versus the control group ENSG00000164172 ENSG00000122420 ENSG00000153130 ENSG00000160013 ENSG00000113070 ENSG00000275190 ENSG00000113140 ENSG00000007908 ENSG00000197780 ENSG00000164120 ENSG00000123219 ENSG00000157426 ENSG00000142892 ENSG00000117054 ENSG00000140835 ENSG00000068976 ENSG00000143315 ENSG00000124882 ENSG00000139133 ENSG00000107611 ENSG00000125255 ENSG00000116761 ENSG00000166446 PMC10607693__F5 Fatty acid biosynthesis and TAG assembly pathway reconstruction ENSG00000089127 ENSG00000158669 ENSG00000285482 ENSG00000186281 ENSG00000062282 ENSG00000026103 PMC7404843__F1 Immune responses and immunotherapy strategy in SARS‐CoV‐2 infection ENSG00000130234 ENSG00000142166 PMC7922062__F3 Glycan-lectin interactions within the breast cancer microenvironment modulate the phenotype of tumour-associated macrophages ENSG00000177575 ENSG00000069482 ENSG00000106178 PMC2671631__F1 The L-arginine biosynthetic pathway and its association to proline and polyamine biosynthesis ENSG00000124357 PMC7827907__F1 Updated Insights on EGFR Signaling Pathways in Glioma ENSG00000291971 ENSG00000198793 ENSG00000146648 ENSG00000196712 PMC8435626__F8 Integrated Phytochemical Analysis Based on UPLC–MS/MS and Network Pharmacology Approaches to Explore the Effect of Odontites vulgaris Moench on Rheumatoid Arthritis ENSG00000142192 PMC11540160__F1G SOX4 protein in the nucleus of CD31+ HemECs binds to the downstream target gene ESM1, further activating the PI3K/AKT signaling pathway ENSG00000164283 ENSG00000291971 ENSG00000198793 ENSG00000124766 ENSG00000112715 PMC99857__F9 The B(a)P-induced apoptotic signaling pathway, which is mediated by APIX ENSG00000070831 ENSG00000149269 PMC6037111__F2 Consequences of hepatic fructose metabolism ENSG00000131473 ENSG00000198670 ENSG00000026103 PMC4667854__F2 Molecular events involving IRFs in immune responses ENSG00000213928 ENSG00000239732 ENSG00000115415 ENSG00000140968 ENSG00000137265 ENSG00000172936 ENSG00000136869 ENSG00000168310 ENSG00000125347 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC5390468__F2 KEGG TGF-beta signalling pathway ENSG00000049323 ENSG00000123999 ENSG00000141232 ENSG00000262634 ENSG00000039319 ENSG00000095739 ENSG00000183691 ENSG00000134363 ENSG00000106100 PMC4813201__F1 Relevant intracellular signal transduction pathways of local anesthetic-induced toxicity ENSG00000002330 ENSG00000070831 ENSG00000291971 ENSG00000134982 ENSG00000010810 ENSG00000177606 ENSG00000136997 ENSG00000168036 ENSG00000168040 ENSG00000128602 ENSG00000168610 PMC7452060__F1 circSETD3 Contributes to Acquired Resistance to Gefitinib in Non-Small-Cell Lung Cancer by Targeting the miR-520h/ABCG2 Pathway ENSG00000183576 ENSG00000118777 PMC6135632__F10 The signaling pathway regulating RAB26-induced SRC degradation (a) Under normal physiological conditions, RAB26 interacts with ATG16L1, resulting in the induction of autophagy, which targets phosphorylated SRC for degradation ENSG00000291971 ENSG00000167964 PMC3886269__F4 Inducible antioxidant defense regulated by Nrf2/Keap1 and the antioxidant response element ENSG00000105227 ENSG00000079999 PMC11678013__F2 “Disease-Pathway-Target-Component-Drug” network ENSG00000172831 ENSG00000164129 ENSG00000114200 ENSG00000105835 ENSG00000178999 ENSG00000283082 ENSG00000069667 ENSG00000126218 ENSG00000082175 ENSG00000157227 ENSG00000188257 ENSG00000001626 ENSG00000112759 ENSG00000197506 ENSG00000262406 ENSG00000142192 ENSG00000161905 ENSG00000198408 ENSG00000100448 ENSG00000131747 ENSG00000101180 ENSG00000173083 ENSG00000099194 ENSG00000075073 ENSG00000132170 ENSG00000117480 ENSG00000107854 ENSG00000146070 ENSG00000074410 ENSG00000198355 ENSG00000162711 ENSG00000163629 ENSG00000291971 ENSG00000181104 ENSG00000087085 ENSG00000169032 ENSG00000135341 ENSG00000158125 ENSG00000177272 ENSG00000128052 ENSG00000166501 ENSG00000123374 ENSG00000037280 ENSG00000167434 ENSG00000168748 ENSG00000142627 ENSG00000150594 ENSG00000137673 ENSG00000157764 ENSG00000086991 ENSG00000135446 ENSG00000103546 ENSG00000177606 ENSG00000180616 ENSG00000142731 ENSG00000100985 ENSG00000105426 ENSG00000159399 ENSG00000173273 ENSG00000167601 ENSG00000143799 ENSG00000157404 ENSG00000168961 ENSG00000122025 ENSG00000134086 ENSG00000104549 ENSG00000101958 ENSG00000105810 ENSG00000077782 ENSG00000276996 ENSG00000106682 ENSG00000087245 ENSG00000162551 ENSG00000125384 ENSG00000007171 ENSG00000167780 ENSG00000108839 ENSG00000151617 ENSG00000146648 ENSG00000172893 ENSG00000113161 ENSG00000087586 ENSG00000148344 ENSG00000145386 ENSG00000166851 ENSG00000118777 ENSG00000010671 ENSG00000292210 ENSG00000106546 ENSG00000180210 ENSG00000117525 ENSG00000185015 ENSG00000165841 ENSG00000149968 ENSG00000129214 ENSG00000196549 ENSG00000170430 ENSG00000111142 ENSG00000253729 ENSG00000278195 ENSG00000263097 ENSG00000027075 ENSG00000086696 ENSG00000171105 ENSG00000235268 ENSG00000104365 ENSG00000188822 ENSG00000108786 ENSG00000132911 ENSG00000160013 ENSG00000081237 ENSG00000196839 ENSG00000170425 ENSG00000073756 ENSG00000132671 ENSG00000196411 ENSG00000177189 ENSG00000156110 ENSG00000164362 ENSG00000008130 ENSG00000198911 ENSG00000176387 PMC3174208__F1 Comprehensive Association Analysis of Homocysteine Metabolic Pathway Genes in Singaporean Chinese with Ischemic Stroke ENSG00000228716 ENSG00000065911 ENSG00000173638 ENSG00000116984 ENSG00000284320 ENSG00000151224 ENSG00000100714 ENSG00000134827 ENSG00000005421 ENSG00000124275 ENSG00000185339 ENSG00000123505 ENSG00000110195 ENSG00000116761 ENSG00000016391 PMC6545262__F2 The Notch pathway in human and mouse Th2 cell development and function ENSG00000111537 ENSG00000107485 PMC8533628__F16 Inhibition of Membrane-Associated Catalase, Extracellular ROS/RNS Signaling and Aquaporin/H2O2-Mediated Intracellular Glutathione Depletion Cooperate during Apoptosis Induction in the Human Gastric Carcinoma Cell Line MKN-45 ENSG00000167419 PMC4573851__F2 The roles of FANCM family proteins in replication fork repair and crossover control ENSG00000198887 ENSG00000187790 ENSG00000197299 ENSG00000178966 PMC4573851__F1 FANCM and partner proteins in coping with template lesions during DNA replication ENSG00000131944 ENSG00000175054 ENSG00000164053 ENSG00000187790 ENSG00000197299 PMC7896717__F3 Gene networks showing signatures of pervasive positive selection in Han Chinese and/or Japanese populations according to signet analysis performed on whole genome distribution of nSL scores and aimed at testing for polygenic adaptation ENSG00000067606 ENSG00000149782 ENSG00000127528 ENSG00000074771 PMC4114643__F2 Osteoclast differentiation and bone resorption by Rho GTPases ENSG00000070831 ENSG00000175104 ENSG00000082212 ENSG00000131196 ENSG00000284984 PMC11592687__F3 Oxidative stress activates Hippo signaling pathway ENSG00000186575 ENSG00000069869 ENSG00000150457 ENSG00000131023 ENSG00000079999 PMC11592687__F2 Hippo signaling pathway in ROS production ENSG00000150907 ENSG00000150457 ENSG00000131023 PMC11592687__F1 Core components of the Hippo signaling pathway and their upstream regulators ENSG00000186575 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC4535673__F3 Profiles of central and oxidative stress response metabolism pathways of K ENSG00000074800 ENSG00000100412 ENSG00000146701 PMC11772995__F6 Corticosterone-induced postpartum depression induces depression-like behavior and impairs hippocampal neurogenesis in adolescent offspring via HPA axis and BDNF-mTOR pathway ENSG00000198793 ENSG00000077279 PMC9152203__F3 Plasma proteomics reveals an improved cardio-metabolic profile in patients with type 2 diabetes post-liraglutide treatment ENSG00000196136 ENSG00000138207 ENSG00000186395 ENSG00000104760 ENSG00000169032 PMC8533628__F13 Inhibition of Membrane-Associated Catalase, Extracellular ROS/RNS Signaling and Aquaporin/H2O2-Mediated Intracellular Glutathione Depletion Cooperate during Apoptosis Induction in the Human Gastric Carcinoma Cell Line MKN-45 ENSG00000166402 ENSG00000167419 PMC4695067__F6 Trypsinogen 4 boosts tumor endothelial cells migration through proteolysis of tissue factor pathway inhibitor-2 ENSG00000138798 PMC8155723__F3 Pathogenesis and Function of Interleukin-35 in Rheumatoid Arthritis ENSG00000138378 ENSG00000115415 ENSG00000105246 PMC10376197__F4 TRP Channels in Tumoral Processes Mediated by Oxidative Stress and Inflammation ENSG00000092439 ENSG00000291971 PMC10243030__F7 NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway ENSG00000170558 ENSG00000113161 PMC5618535__F2 PALB2 in the DNA damage repair ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000083093 ENSG00000138346 ENSG00000051180 ENSG00000139618 PMC8961363__F3 Floral Scents and Fruit Aromas: Functions, Compositions, Biosynthesis, and Regulation ENSG00000039537 ENSG00000113600 PMC8001967__F3 Mitochondrial regulation of ferroptosis ENSG00000161016 ENSG00000167107 ENSG00000156398 ENSG00000196365 ENSG00000062485 PMC2787666__F2 The complex network of protein–protein interactions of Ape1 ENSG00000132906 ENSG00000039650 ENSG00000112039 ENSG00000112715 ENSG00000149554 ENSG00000064933 PMC5384343__F2 MTOR signaling pathway ENSG00000169047 ENSG00000155792 ENSG00000146648 PMC3260548__F1 The signaling cascade in response to the release of dsRNA from LRV particles, production of IFNB and secretion of proinflammatory cytokines and chemokines ENSG00000169245 ENSG00000239732 ENSG00000172936 ENSG00000164342 PMC8348654__F1 Failure to Guard: Mitochondrial Protein Quality Control in Cancer PMC7828172__F2 ROR1 signaling ENSG00000070831 ENSG00000291971 ENSG00000198793 ENSG00000173039 ENSG00000162849 ENSG00000185483 ENSG00000002745 ENSG00000171791 ENSG00000168610 ENSG00000164305 ENSG00000168283 ENSG00000124216 ENSG00000100592 ENSG00000134057 ENSG00000135446 ENSG00000177606 ENSG00000111186 PMC6595721__F2 Major mechanisms regulated by SUMOs and SUMOylation in kidney disease ENSG00000134086 ENSG00000157933 ENSG00000173039 ENSG00000159335 PMC4030106__F1 Roles of IL-21 and IRF4 in immune and metabolic regulation ENSG00000150907 ENSG00000137265 ENSG00000103522 ENSG00000049768 ENSG00000168610 PMC2787666__F1 Base excision repair (BER) pathway ENSG00000143799 ENSG00000132646 PMC7828172__F3 ROR2 signaling ENSG00000087245 ENSG00000169071 ENSG00000070831 ENSG00000291971 ENSG00000198793 ENSG00000162849 ENSG00000118971 ENSG00000168610 ENSG00000100592 ENSG00000132646 ENSG00000177606 ENSG00000019549 ENSG00000111186 ENSG00000100985 PMC4890876__F3 All of animal cells may be intrinsically programmed to self-destruct ENSG00000102871 ENSG00000171791 ENSG00000168040 PMC2667944__F1 Angiotensin converting enzyme 2 in the brain ENSG00000130234 PMC11575309__F7 DLL4-targeted CAR-T therapy sensitizes neoadjuvant chemotherapy via eliminating cancer stem cells and reshaping immune microenvironment in HER2+ breast cancer ENSG00000277571 ENSG00000168214 ENSG00000128917 ENSG00000155660 ENSG00000005381 PMC3348497__F1 Insulin-like growth factor (IGF)-1 signal transduction ENSG00000169047 ENSG00000140443 PMC7226328__F4 Network analysis by Ingenuity Pathway Analysis (IPA) ENSG00000171246 ENSG00000107562 ENSG00000005339 ENSG00000292234 ENSG00000152766 ENSG00000106483 ENSG00000112715 ENSG00000197467 ENSG00000179915 PMC10376197__F3 TRP Channels in Tumoral Processes Mediated by Oxidative Stress and Inflammation ENSG00000104321 ENSG00000138741 ENSG00000196689 PMC10376197__F2 TRP Channels in Tumoral Processes Mediated by Oxidative Stress and Inflammation ENSG00000092439 ENSG00000128272 PMC3926887__F6 Novel antioxidants are not toxic to normal tissues but effectively kill cancer cells ENSG00000087095 ENSG00000170458 ENSG00000130159 ENSG00000026103 PMC8533075__F10 Salvianolic Acid C Protects against Cisplatin-Induced Acute Kidney Injury through Attenuation of Inflammation, Oxidative Stress and Apoptotic Effects and Activation of the CaMKK–AMPK–Sirt1-Associated Signaling Pathway in Mouse Models ENSG00000211445 ENSG00000132478 ENSG00000136869 ENSG00000096717 PMC9387421__F3 Zinc delays the progression of lung disease by affecting a variety of signaling pathways ENSG00000002330 ENSG00000125538 ENSG00000198793 PMC3652739__F4 Microarray analysis also indicated an increase in Wnt signaling and cell cycle regulation in women ENSG00000228716 ENSG00000132646 ENSG00000136997 PMC7226441__F2 Innate and Adaptive Immunity Linked to Recognition of Antigens Shared by Neural Crest-Derived Tumors ENSG00000134982 ENSG00000170558 ENSG00000168610 ENSG00000121966 PMC9428319__F3 Pathomechanisms of bone loss in rheumatoid arthritis ENSG00000167941 PMC5751940__F1 TumorMap framework and application to the analysis of the TCGA Pan-Cancer-12 Dataset ENSG00000157557 ENSG00000157404 ENSG00000081237 ENSG00000177606 ENSG00000166501 ENSG00000122877 ENSG00000131196 PMC4753150__F4 Vitamin D and Calcium Regulation of Epidermal Wound Healing ENSG00000156076 ENSG00000168036 ENSG00000163132 ENSG00000104332 ENSG00000176153 ENSG00000117399 ENSG00000196628 ENSG00000214114 ENSG00000125285 ENSG00000169474 ENSG00000125686 ENSG00000026508 ENSG00000285438 ENSG00000168646 PMC3582304__F2 Therapeutic targets of the Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8706120__F3 Roles of the Virome in Cancer PMC3582304__F1 Diagrammatic representation of the canonical Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5568901__F1 Antiviral mechanisms in mammalian cells: IFN-based antiviral system, including IFN expression pathway (AE) and IFN response pathway (AR); the intrinsic antiviral pathway (B); and the RNAi antiviral pathway (C) ENSG00000164430 ENSG00000105397 ENSG00000135828 ENSG00000164342 PMC9170969__F1 Antiviral immune response by African swine fever virus (ASFV) ENSG00000159128 ENSG00000213928 ENSG00000164430 ENSG00000088888 ENSG00000111537 ENSG00000105397 ENSG00000136869 ENSG00000133135 ENSG00000164342 PMC9170969__F3 Antiviral immune response by African swine fever virus (ASFV) ENSG00000128272 ENSG00000144895 ENSG00000102871 ENSG00000083799 ENSG00000171791 ENSG00000127191 PMC6338618__F7 Proposed model for the role of inhibition of BCLM by Ponatinib ENSG00000167772 ENSG00000041982 ENSG00000177606 ENSG00000073756 PMC8255676__F1 Ferroptosis Holds Novel Promise in Treatment of Cancer Mediated by Non-coding RNAs ENSG00000151012 ENSG00000205221 ENSG00000167468 ENSG00000111371 ENSG00000115419 PMC8590218__F4 Gene profiling of Toll-like receptor signalling pathways in neutrophils of patients with acute-on-chronic liver failure ENSG00000135218 ENSG00000131323 ENSG00000150455 ENSG00000125347 ENSG00000175104 ENSG00000164342 ENSG00000143387 PMC2827926__F3 The refined scheme of the glyoxylate regeneration cycle, now termed ethylmalonyl-CoA pathway (right), and its connection to the serine cycle (left) ENSG00000261701 PMC8093191__F1 miRNAs affect animal behavior related to MDD and BD by regulating the expression of genes involved in serotonergic neurotransmission and signaling pathways activated by glucocorticoids, BDNF, Wnt, and guidance cues ENSG00000134982 ENSG00000118515 ENSG00000168036 ENSG00000096717 PMC4335796__F1 NLR-mediated suppression of canonical and non-canonical NFKB signaling ENSG00000104856 ENSG00000167207 ENSG00000160703 ENSG00000174885 ENSG00000142405 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC3312985__F4 Genes identified as part of the significant Para-ICA networks highlighted on a KEGG Alzheimer’s pathway diagram derived from the DAVID functional association tool ENSG00000002330 ENSG00000173599 ENSG00000168040 ENSG00000081051 ENSG00000119912 ENSG00000164305 PMC6895177__F8 Pyroptosis is a critical inflammatory pathway in the placenta from early onset preeclampsia and in human trophoblasts exposed to hypoxia and endoplasmic reticulum stressors ENSG00000162711 ENSG00000125538 ENSG00000189403 ENSG00000265972 PMC8387910__F1 Adiponectin gene polymorphisms associated with diabetes mellitus: A descriptive review ENSG00000159346 ENSG00000285070 PMC7827308__F8 Simplified representation of intracellular pathways activated upon TLR activation and working mechanism of B18R ENSG00000160710 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC8841753__F2 Peptide-Based Vaccines for Tuberculosis ENSG00000174125 ENSG00000108691 ENSG00000172936 PMC11597542__F2 TLR and RLR signaling pathways and LNP effects ENSG00000150782 ENSG00000239732 ENSG00000088888 ENSG00000163739 ENSG00000172936 ENSG00000175104 PMC8136793__F1 Repriming DNA synthesis: an intrinsic restart pathway that maintains efficient genome replication ENSG00000164306 ENSG00000051180 PMC5940413__F5 Functional significance of co-occurring mutations in PIK3CA and MAP3K1 in breast cancer ENSG00000169047 ENSG00000198793 ENSG00000095015 ENSG00000121879 PMC7338517__F6 Spermidine activates RIP1 deubiquitination to inhibit TNF-Alpha-induced NFKB/p65 signaling pathway in osteoarthritis ENSG00000149968 PMC2958230__F1 Effect of TBCD and its Regulatory Interactor Arl2 on Tubulin and Microtubule Integrity ENSG00000141556 ENSG00000213465 ENSG00000105254 ENSG00000284770 ENSG00000124659 PMC8136793__F3 Repriming DNA synthesis: an intrinsic restart pathway that maintains efficient genome replication ENSG00000132646 ENSG00000164306 PMC11641610__F3 Key signaling pathways involved in T cell senescence within the tumor microenvironment ENSG00000149311 ENSG00000291603 ENSG00000198793 ENSG00000276051 ENSG00000164362 PMC5195921__F8 G protein-coupled bile acid receptor plays a key role in bile acid metabolism and fasting-induced hepatic steatosis ENSG00000135218 ENSG00000112964 ENSG00000105550 ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC6704447__F11 Model for Rac1 involvement in TGFB1–driven renal fibrosis ENSG00000291971 ENSG00000146648 PMC3973904__F1 Cholesterol metabolism, lipid rafts and autism spectrum disorders ENSG00000130164 ENSG00000036530 ENSG00000113161 ENSG00000104549 PMC5411428__F1 Proteostasis network and ALS ENSG00000112367 ENSG00000183735 ENSG00000128272 ENSG00000106460 ENSG00000165280 ENSG00000100219 ENSG00000147894 PMC5579367__F1 Live and let die: ZBP1 senses viral and cellular RNAs to trigger necroptosis ENSG00000124256 ENSG00000164430 ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC9393224__F3 RNA binding proteins in osteoarthritis ENSG00000128016 ENSG00000125398 ENSG00000149658 ENSG00000156427 ENSG00000136869 ENSG00000276833 ENSG00000171791 ENSG00000163938 PMC4772380__F10 HCV induces transforming growth factor B1 through activation of endoplasmic reticulum stress and the unfolded protein response ENSG00000128272 ENSG00000162772 PMC6523516__F7 Molecular mechanism through which high glucose (HG) concentration promotes proliferation and migration in colorectal cancer (CRC) cells ENSG00000134057 ENSG00000291971 ENSG00000140443 PMC5053399__F1 Identification of novel peptoid agonists of fibroblast growth factor receptor using microarray-based screening PMC9162355__F10 1,2,3,6-Tetra-O-galoyl-Beta-D-glucose induced apoptosis signalling pathway in SGC7901 cells ENSG00000149311 ENSG00000120868 PMC6996149__F4 Major cholesterol metabolic pathways in brain ENSG00000138135 ENSG00000036530 ENSG00000099377 ENSG00000135929 PMC6996149__F3 Regulatory factors of the acidic pathway of bile acid synthesis ENSG00000197063 ENSG00000135929 PMC6996149__F2 Acidic pathway of bile acid synthesis in metabolic regulations ENSG00000138075 ENSG00000143921 ENSG00000026103 PMC6996149__F1 Two major pathways of bile acid synthesis in mammalian liver ENSG00000138135 ENSG00000167910 ENSG00000036530 ENSG00000180432 ENSG00000099377 ENSG00000135929 PMC8212140__F3 Reactive oxygen species produced by altered tumor metabolism impacts cancer stem cell maintenance ENSG00000136997 ENSG00000026508 ENSG00000159399 PMC5789368__F1 Key players in the mammalian autophagy pathway discussed in this review ENSG00000177169 ENSG00000126775 ENSG00000112561 PMC3689841__F1 Computational Model of Gab1/2-Dependent VEGFR2 Pathway to Akt Activation ENSG00000169291 ENSG00000033327 PMC6471273__F1 Biosynthetic pathway of ginsenosides according to ENSG00000110921 ENSG00000197429 ENSG00000139687 PMC11787699__F1 YAP/TAZ in soluble biological signals in bone ENSG00000170365 ENSG00000163914 ENSG00000198670 PMC5560141__F2 The EGFR signaling pathway involving CEMIP mediation ENSG00000291971 ENSG00000138798 ENSG00000103888 PMC4825606__F1 Diagram of the roles and its signaling pathway of Cyclin B3 in oocyte meiosis ENSG00000134057 ENSG00000134982 ENSG00000147082 PMC8042443__F7 A, schematic diagram showing two separate DGKζ signaling complexes, one for Rac1 activation (left) and one for RhoA activation (right) ENSG00000149269 ENSG00000198670 PMC6496019__F7 Schematic diagram proposed by the present research ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC2789784__F2 Signaling pathway downstream of PI3K affect cell death and cell survival ENSG00000124102 ENSG00000005882 ENSG00000198793 PMC2536507__F2 Pathogen recognition systems ENSG00000131323 ENSG00000175104 PMC4422111__F4 Kreb's cycle used to determine relative flux rates through acetyl-CoA synthetase (ACS), pyruvate dehydrogenase complex (PDH), pyruvate carboxylase (PC), and glutamate dehydrogenase (GDH) ENSG00000173599 ENSG00000172005 ENSG00000062485 PMC2330263__F2 Integration of Progesterone Receptor Action with Rapid Signaling Events in Breast Cancer Models ENSG00000291971 PMC5701508__F1 The crossroads of breast cancer progression: insights into the modulation of major signaling pathways ENSG00000113070 ENSG00000173039 ENSG00000185591 ENSG00000111816 ENSG00000146648 PMC11747557__F6 Active ingredients of Radix Codonopsis exert anticancer effects in gastric and livercancer PMC4397019__F7 Atypical Protein Kinase C Zeta: Potential Player in Cell Survival and Cell Migration of Ovarian Cancer ENSG00000259207 ENSG00000067606 PMC11747557__F5 Active components of Radix Codonopsis promote lung cancer cell death and inhibitinvasion and metastasis ENSG00000132906 ENSG00000002330 ENSG00000102871 ENSG00000082512 ENSG00000127191 PMC12023346__F7 The effects of intraamniotic LPS exposure on the TRP metabolic pathways in the placenta and fetal brain ENSG00000139287 ENSG00000129167 ENSG00000188676 PMC59539__F2 Schematic model of Shh/Fgf10/Bmp4 signalling during lung branching morphogenesis ENSG00000066468 ENSG00000070193 ENSG00000164690 ENSG00000128602 PMC59539__F1 The Hh signalling pathway, based on what is known in flies ENSG00000166278 ENSG00000128602 PMC11000535__F3 STAT3, EMT-TFs, miRNAs and lncRNAs form complex network to regulate EMT ENSG00000122691 ENSG00000168610 PMC4846185__F7 ARF1 in mediating gefitinib sensitivity in breast cancer cells ENSG00000167601 ENSG00000143761 ENSG00000291971 ENSG00000146648 PMC8216565__F10 Apoptosis signaling pathway ENSG00000149311 ENSG00000110711 ENSG00000142192 ENSG00000128272 ENSG00000168803 ENSG00000038002 ENSG00000168040 ENSG00000164949 ENSG00000084774 PMC12023346__F1 Tryptophan metabolic pathway ENSG00000162882 ENSG00000183077 PMC7169063__F1 IFN production pathway and different ways that the virus disrupts this pathway ENSG00000183735 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC3060584__F6 ‘Integrative Physiology 2.0’: integration of systems biology into physiology and its application to cardiovascular homeostasis ENSG00000106927 PMC7169063__F2 IFN signaling pathway and different ways that the virus interferes with this pathway ENSG00000213928 ENSG00000105397 PMC5354237__F2 Systemic damage responses of the fat body methionine metabolism (A) Methionine metabolism in Drosophila PMC5675701__F8 Long non-coding RNA CRNDE acts as a ceRNA and promotes glioma malignancy by preventing miR-136-5p-mediated downregulation of Bcl-2 and Wnt2 ENSG00000198793 PMC3035979__F2 Gene expression profile ENSG00000041982 PMC4406277__F4 Pathway visualization ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000112576 ENSG00000105329 ENSG00000197629 ENSG00000250254 ENSG00000118971 ENSG00000139687 ENSG00000134480 ENSG00000253729 ENSG00000175305 PMC3559342__F4 Genome-Wide Pathway Analysis Reveals Different Signaling Pathways between Secreted Lactoferrin and Intracellular Delta-Lactoferrin ENSG00000115216 ENSG00000136929 ENSG00000261832 ENSG00000071655 ENSG00000065000 ENSG00000140829 ENSG00000105613 ENSG00000263956 ENSG00000060069 ENSG00000124228 ENSG00000101811 ENSG00000105607 ENSG00000146192 ENSG00000106723 ENSG00000088002 ENSG00000215021 ENSG00000273772 ENSG00000147955 ENSG00000076321 ENSG00000205937 ENSG00000145216 PMC4542009__F1 Tumor Angiogenesis ENSG00000134086 ENSG00000291971 ENSG00000118257 ENSG00000146648 PMC3559342__F3 Genome-Wide Pathway Analysis Reveals Different Signaling Pathways between Secreted Lactoferrin and Intracellular Delta-Lactoferrin ENSG00000091972 ENSG00000110107 ENSG00000101115 ENSG00000147138 ENSG00000107447 ENSG00000177600 PMC3885718__F6 Resveratrol Induces Vascular Smooth Muscle Cell Differentiation through Stimulation of SirT1 and AMPK ENSG00000169047 ENSG00000096717 PMC4527020__F1 Location and signaling pathways of pattern recognition receptors ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000276561 ENSG00000164342 PMC8235326__F2 Ca2+ Signaling and Its Potential Targeting in Pancreatic Ductal Carcinoma ENSG00000002330 ENSG00000042832 ENSG00000167323 ENSG00000293604 ENSG00000156026 ENSG00000196154 PMC8235326__F1 Ca2+ Signaling and Its Potential Targeting in Pancreatic Ductal Carcinoma ENSG00000253506 ENSG00000167323 ENSG00000293604 ENSG00000156026 ENSG00000274112 PMC4034727__F1 LncRNAs associated with the p53 pathway ENSG00000141499 PMC8458797__F1 Complement Factor D as a Strategic Target for Regulating the Alternative Complement Pathway ENSG00000039537 PMC5701508__F2 PI3K signaling pathway.Notes: (A) Activation of receptor tyrosine kinase (RTK) by a ligand results in phosphorylation of the receptor and adaptor proteins ENSG00000069482 ENSG00000198793 PMC5701508__F5 Wnt pathways.Notes: (A) Planar cell polarity (PCP) Wnt pathway in “off” state, with no ligand bound to Fzd receptor leads to Beta-catenin proteasome degradation ENSG00000134982 ENSG00000163914 PMC5701508__F4 JAK–STAT signaling pathway.Notes: (A) Specific ligands bind to membrane receptors, leading to dimerization, which promotes JAK activation and transphosphorylation, which in turn phosphorylates STAT, prompting its dimerization ENSG00000120833 ENSG00000115415 ENSG00000168610 PMC5981260__F2 Tumor suppressor molecules signaling ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000178573 PMC8289457__F6 Pediatric Pulmonary Hypertension: Definitions, Mechanisms, Diagnosis, and Treatment ENSG00000137834 ENSG00000198742 ENSG00000168036 ENSG00000283060 ENSG00000204217 ENSG00000125968 PMC5701508__F8 NFKB pathway.Notes: (A) The canonical pathway starts with binding of TNF to its receptor, activating the IKK complex, which phosphorylates IKBA, promoting its polyubiquitination and further proteasome-dependent degradation ENSG00000104856 ENSG00000111321 PMC4684398__F6 Nontypeable Haemophilus influenzae-Induced MyD88 Short Expression Is Regulated by Positive IKKB and CREB Pathways and Negative ERK1/2 Pathway ENSG00000172936 ENSG00000184216 PMC12111433__F6 This illustration depicts the pathways and key genes involved in the synthesis of chlorophyll and SGAs during the photoinduced greening of potato tubers ENSG00000126088 ENSG00000163479 ENSG00000127948 PMC11954216__F5 Naturally occurring products that inhibit mTOR in BCSCs ENSG00000151376 ENSG00000198793 PMC7968835__F3 Towering genome: Experimentally validated adaptations to high blood pressure and extreme stature in the giraffe ENSG00000284953 PMC11954216__F2 The mTOR pathway in breast cancer stem cells (BCSCs): mechanisms and therapeutic potentials ENSG00000113905 ENSG00000142227 ENSG00000101000 ENSG00000111728 ENSG00000026508 ENSG00000140443 PMC11954216__F1 Cellular Mechanisms of mTOR in BCSCs: This schematic illustrates the multifaceted roles of mTOR in regulating cellular functions in BCSCs, with implications in metastasis, metabolism, autophagy, and ferroptosis ENSG00000094631 ENSG00000177169 ENSG00000125398 ENSG00000198793 PMC11954216__F3 Targeting the PI3K/Akt/mTOR Pathway in BCSCs with synthetic drugs: This figure depicts synthetic inhibitors targeting the PI3K/Akt/mTOR pathway in BCSCs to reduce survival, proliferation, and resistance ENSG00000148400 ENSG00000198793 ENSG00000146648 PMC3670175__F1 Quantitative proteomics by amino acid labeling identifies novel NHR-49 regulated proteins in C. elegans ENSG00000083857 ENSG00000161533 PMC9604078__F1 Rationale for Combining the BCL2 Inhibitor Venetoclax with the PI3K Inhibitor Bimiralisib in the Treatment of IDH2- and FLT3-Mutated Acute Myeloid Leukemia ENSG00000122025 ENSG00000168283 ENSG00000198793 ENSG00000171791 ENSG00000168610 ENSG00000124762 ENSG00000179295 PMC3186052__F6 Inhibition of prostate cancer cell proliferation through statin use, and its impact on the HMG-CoA pathway ENSG00000163914 PMC4731498__F2 Placental mTOR as a nutrient sensing signaling pathway PMC3744028__F9 Summary of the proposed role of Pak1 in mediating stretch-induced CTGF upregulation ENSG00000149269 ENSG00000146648 PMC11933022__F4 TMAO effect on CKD: Three main pathways are depicted: TMAO activates macrophages by stimulating NLRP3 (NOD-like receptor protein 3) and stimulates T cell differentiation to produce multiple inflammatory factors, such as TNFA, IL-6, etc ENSG00000162711 ENSG00000198793 ENSG00000132693 PMC8274167__F1 Metabolic regulators of enigmatic inflammasomes in autoimmune diseases and crosstalk with innate immune receptors ENSG00000278718 ENSG00000162711 ENSG00000226275 ENSG00000088888 ENSG00000163568 ENSG00000125538 ENSG00000160703 ENSG00000174885 ENSG00000091592 ENSG00000091106 ENSG00000175104 ENSG00000276068 PMC9627342__F3 Pathological implications of metabolic reprogramming and its therapeutic potential in medulloblastoma ENSG00000198125 PMC5809401__F9 Schematic representation demonstrating the mechanism by which silibinin inhibits NSCLC metastasis via the EGFR/LOX signaling pathway ENSG00000138798 ENSG00000146648 PMC5369987__F4 Comparative transcriptomic analysis of mice liver treated with different AMPK activators in a mice model of atherosclerosis ENSG00000146592 ENSG00000288174 ENSG00000133124 PMC4720882__F1 Alcohol and HIV-related neuroinflammation and cytotoxicity contribute astrocyte cPLA2 activation into the limelight ENSG00000125538 ENSG00000130649 PMC5216465__F8 Four possible pathways (circles) by which CNP could activate CFTR ENSG00000173786 ENSG00000145321 ENSG00000001626 PMC5852597__F1 The Wnt signaling pathway that determines stem cell self-renewal ENSG00000071564 ENSG00000134982 ENSG00000183579 ENSG00000108375 PMC4310010__F1 Alterations in selected pathways in head and neck squamous cell cancers ENSG00000116044 ENSG00000121879 ENSG00000146648 ENSG00000139687 ENSG00000079999 ENSG00000109670 PMC4704690__F1 Controlling the burn and fueling the fire - defining the role for the alarmin IL-33 in alloimmunity ENSG00000111537 ENSG00000137033 ENSG00000109321 PMC5303602__F6 Schematic describing the effects and proposed response on TLR4 signaling pathway and inflammatory cytokines resulting from resveratrol treatment and HFD ENSG00000170458 ENSG00000125538 ENSG00000136869 ENSG00000175104 PMC5369987__F5 Comparative transcriptomic analysis of mice liver treated with different AMPK activators in a mice model of atherosclerosis ENSG00000182533 ENSG00000171105 ENSG00000156026 ENSG00000186716 PMC3597666__F5 Representation of the top canonical pathway ‘interferon signalling’ detected when simultaneously analysing the mRNA and miRNA data sets with IPA ENSG00000213928 ENSG00000111537 ENSG00000115415 ENSG00000033800 ENSG00000185885 ENSG00000125347 ENSG00000230034 PMC6392285__F8 Calcium signaling pathway by hepatitis C virus core protein stimulates NLRP3 inflammasome activation ENSG00000162711 ENSG00000125538 PMC8293156__F2 Cellular Effects of Rhynchophylline and Relevance to Sleep Regulation ENSG00000132906 ENSG00000116106 ENSG00000078053 ENSG00000010810 ENSG00000172936 ENSG00000166278 ENSG00000164305 PMC8226128__F3 Inflammasomes and Fibrosis ENSG00000162711 ENSG00000189403 ENSG00000265972 ENSG00000079999 PMC4333878__F1 Apoptotic cell death pathways and (b) inhibition of the apoptosis signalling pathway ENSG00000115415 ENSG00000150907 ENSG00000168610 ENSG00000026103 PMC9334798__F1 Mechanisms of Ferroptosis and the Applications in Tumor Treatment: Enemies or Friends? ENSG00000168003 ENSG00000186575 ENSG00000135423 ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000162772 ENSG00000102967 ENSG00000135245 ENSG00000127948 PMC4394621__F7 Kinase targets and inhibitors ENSG00000102871 ENSG00000198793 ENSG00000127191 ENSG00000146648 PMC8237755__F2 WIP, YAP/TAZ and Actin Connections Orchestrate Development and Transformation in the Central Nervous System ENSG00000291971 ENSG00000169047 ENSG00000164327 PMC8237755__F1 WIP, YAP/TAZ and Actin Connections Orchestrate Development and Transformation in the Central Nervous System ENSG00000069482 ENSG00000291971 ENSG00000138798 ENSG00000136997 ENSG00000164327 PMC7281461__F2 Primary pancreatic cancer recruits fibroblasts to become cancer associated fibroblasts (CAFs) ENSG00000197043 ENSG00000050165 ENSG00000078098 PMC6460433__F7 Model for regulation of antiviral innate immunity by BA metabolism ENSG00000291971 ENSG00000137491 ENSG00000135929 PMC4935551__F2 Role of chaperone-mediated autophagy in metabolism ENSG00000130208 ENSG00000155008 ENSG00000062282 ENSG00000062485 PMC8343065__F1 Cell Cycle Commitment and the Origins of Cell Cycle Variability ENSG00000135446 ENSG00000136997 ENSG00000123374 ENSG00000105810 PMC7602737__F5 Suggested mechanisms of action of fenugreek on milk synthesis and secretion ENSG00000171105 ENSG00000112964 ENSG00000198793 ENSG00000169710 ENSG00000122971 PMC5288595__F5 Serum markers that change in response to treatment ENSG00000188379 ENSG00000135218 ENSG00000242689 ENSG00000115457 ENSG00000146678 ENSG00000149294 ENSG00000104918 PMC8954493__F7 Gene Expression over Time during Cell Transformation Due to Non-Genotoxic Carcinogen Treatment of Bhas 42 Cells ENSG00000284320 ENSG00000228716 ENSG00000067064 ENSG00000065911 ENSG00000100714 ENSG00000092621 ENSG00000197429 ENSG00000104549 ENSG00000135069 ENSG00000120437 ENSG00000167508 ENSG00000146733 PMC8795407__F1 The Hippo pathway signalling cascade and its stimuli ENSG00000186575 ENSG00000144560 ENSG00000197905 ENSG00000114978 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC5288595__F2 Steroid-specific protein markers ENSG00000029559 ENSG00000112964 ENSG00000089685 ENSG00000115263 ENSG00000288512 ENSG00000140545 ENSG00000115310 ENSG00000079557 PMC3317229__F4 P38 signalling cascade (adapted from http://www.sabiosciences.com/) ENSG00000162889 ENSG00000099985 ENSG00000170458 ENSG00000291971 ENSG00000130522 ENSG00000114738 PMC3317229__F3 JNK signalling pathway (adapted from http://www.sabiosciences.com/) ENSG00000070831 PMC5430417__F6 Mechanisms involved in the antagonist effect of sinapic acid against UVA-induced attenuation of stemness and differentiation properties of stem cells ENSG00000245848 ENSG00000127528 PMC11592827__F6 Integrative Network Pharmacology, Molecular Docking, and Dynamics Simulations Reveal the Mechanisms of Cinnamomum tamala in Diabetic Nephropathy Treatment: An In Silico Study ENSG00000140992 ENSG00000087245 ENSG00000171105 ENSG00000070831 ENSG00000291971 ENSG00000105639 ENSG00000164305 ENSG00000181019 ENSG00000115415 ENSG00000149968 ENSG00000158874 ENSG00000100985 ENSG00000077782 ENSG00000146648 ENSG00000178568 PMC7961376__F1 Molecular pathways of novel emerging targets in NSCLC and agents in clinical development ENSG00000019991 ENSG00000135446 ENSG00000198793 ENSG00000163914 ENSG00000105810 ENSG00000171119 ENSG00000117407 ENSG00000125650 PMC8674491__F3 Metabolic Reprogramming of Thyroid Cancer Cells and Crosstalk in Their Microenvironment ENSG00000042832 ENSG00000198793 ENSG00000106546 ENSG00000026103 PMC9052532__F3 Gut microbiota influence immunotherapy responses: mechanisms and therapeutic strategies ENSG00000111537 ENSG00000291814 PMC11953061__F3 Protein–protein interaction (PPI) networks of reproducible and differentially expressed proteins (RDEPs) were generated via the STRING database ENSG00000143799 ENSG00000087245 ENSG00000132646 ENSG00000198793 ENSG00000173039 ENSG00000167552 ENSG00000132356 ENSG00000124762 ENSG00000121966 ENSG00000132170 ENSG00000067715 PMC5458753__F1 ZIKV genome structure and signaling transductions underlying ZIKV infection ENSG00000167601 ENSG00000092445 ENSG00000198793 ENSG00000164342 PMC8052633__F3 Interplay between p62-mediated autophagy and the cGAS-STING-mediated DNA sensing pathway ENSG00000149311 ENSG00000177169 ENSG00000183735 ENSG00000164430 ENSG00000198793 PMC7026265__F4 Pharmacological strategies to control endoplasmic reticulum (ER) stress in diseases ENSG00000128272 ENSG00000144895 ENSG00000257727 ENSG00000100219 PMC7053098__F5 Cisplatin-induced P53 signaling pathway genes are differentially expressed between Sirt2-deficient and Sirt2-proficient cells ENSG00000149311 ENSG00000132906 ENSG00000175054 ENSG00000136997 ENSG00000123374 ENSG00000196470 ENSG00000164305 ENSG00000111962 PMC7096376__F2 NAD biosynthetic pathways ENSG00000105835 ENSG00000123572 ENSG00000278488 PMC7096376__F1 Intra/extra NAD interconnections and NAD-metabolizing enzymes ENSG00000105835 ENSG00000197594 PMC7026265__F1 Emerging Roles of Endoplasmic Reticulum Stress in Balancing Immunity and Tolerance in Health and Diseases: Mechanisms and Opportunities ENSG00000128272 ENSG00000144895 ENSG00000257727 ENSG00000100219 ENSG00000127191 PMC4843516__F2 Neuroendocrine pathways regulate stress tolerance in C ENSG00000118515 ENSG00000189430 ENSG00000096264 PMC8052633__F2 Interplay between autophagy and DDR ENSG00000143799 ENSG00000149311 ENSG00000012048 ENSG00000177169 ENSG00000163961 ENSG00000198793 ENSG00000051180 ENSG00000171791 PMC9163742__F3 Prospective Application of Melatonin in Treating Epigenetic Dysfunctional Diseases ENSG00000189079 PMC8859442__F2 Understanding Reactive Oxygen Species in Bone Regeneration: A Glance at Potential Therapeutics and Bioengineering Applications ENSG00000178860 ENSG00000086991 PMC8192769__F5 Schematic diagram of the effects of fadraciclib at 4 h ENSG00000002330 ENSG00000115317 PMC8001868__F5 Summary of some of the effects of allicin on eukaryotic cells ENSG00000154059 ENSG00000079999 PMC10343400__F6 Glycosides and UC-related receptors AND transcriptional regulation ENSG00000162711 ENSG00000181019 ENSG00000136869 PMC8453895__F3 Contribution of irisin pathway in protective effects of mandarin juice (Citrus reticulata Blanco) on metabolic syndrome in rats fed with high fat diet ENSG00000160097 ENSG00000132170 PMC5894358__F11 The schematic diagram of potential molecular mechanisms of anti-inflammation effects of recombinant human Netrin-1 (rh-NTN-1) through UNC5B/PPARG/NFKB signaling pathway after SAH ENSG00000065320 ENSG00000107731 ENSG00000005381 PMC6746704__F8 Elevated FAM83A expression in pancreatic cancers is driven by a MEK/ERK-JUNB-driven feed-forward signalling loop ENSG00000125740 ENSG00000147689 PMC134648__F8 Role of Axin2 in Wnt signal transduction ENSG00000134982 ENSG00000168036 ENSG00000167074 ENSG00000168646 PMC2860204__F4 Integrin signalling at focal adhesions ENSG00000033327 ENSG00000291971 ENSG00000010810 PMC9603070__F10 Melatonin Enhances Drought Tolerance in Rice Seedlings by Modulating Antioxidant Systems, Osmoregulation, and Corresponding Gene Expression PMC4221543__F1 The MAPK/ERK pathway ENSG00000124102 ENSG00000291971 ENSG00000198793 ENSG00000146648 PMC8750957__F2 TNF-Induced Osteoclast Differentiation ENSG00000104856 ENSG00000173039 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC8307807__F3 Wnt Signaling by FOX Transcription Factors in Cancer ENSG00000168036 ENSG00000204612 PMC3038089__F2 Biological consequences of methylation on Rho-RhoGDI interaction ENSG00000163914 ENSG00000171540 ENSG00000116237 PMC3382540__F1 ERK signaling pathway controls T-cell activation and anergy ENSG00000291603 PMC8307807__F1 Wnt Signaling by FOX Transcription Factors in Cancer ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC6292965__F9 DT-13 promoted mitochondrial apoptosis and inhibited metastasis via suppressing PI3K/Akt pathway ENSG00000132906 ENSG00000002330 ENSG00000164305 PMC3170456__F1 Autophagy in Cancer: Therapeutic Implications ENSG00000152348 ENSG00000198793 ENSG00000144848 ENSG00000005893 ENSG00000167965 ENSG00000171791 ENSG00000145782 ENSG00000140464 ENSG00000057663 PMC4333878__F2 EBV interaction with the Bcl family ENSG00000019582 PMC7665122__F2 Signaling pathway induced by aPL ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC9686959__F2 Ferroptosis and Its Potential Role in Glioma: From Molecular Mechanisms to Therapeutic Opportunities ENSG00000168003 ENSG00000167468 ENSG00000111684 PMC9542548__F5 Mitochondrial protein Sideroflexin 3 (SFXN3) influences neurodegeneration pathways in vivo ENSG00000178752 ENSG00000158578 ENSG00000105697 PMC3187864__F6 Axon viability depends on coordinated endocytic trafficking and signaling ENSG00000274145 PMC3491533__F8 Diagrammatic presentation shows how Notch and TGFB signaling pathway involved at each pathogenic stage of HBV infection ENSG00000049768 PMC8036441__F5 Quercetin apoptotic mechanism via death ligand and mitochondrial membrane ENSG00000002330 PMC6323527__F2 Variety of factors control Tn cell survival and metabolic pathway engagement after T cell activation ENSG00000151012 ENSG00000227345 ENSG00000132170 ENSG00000026103 PMC6323527__F1 Core metabolic pathways for T cell survival, activation, differentiation, and function ENSG00000291971 ENSG00000166278 PMC5757446__F2 Current and proposed molecular mechanisms augmenting myogenic reactivity in subarachnoid hemorrhage ENSG00000118785 ENSG00000001626 PMC3893574__F1 MiRNAs involved in the regulation of the IGF-1/Akt pathway and myostatin signaling ENSG00000169047 ENSG00000198793 ENSG00000140443 PMC4067963__F10 Model of Sox9, Sox10 and FGF function during lacrimal gland branching morphogenesis ENSG00000139219 ENSG00000066468 ENSG00000070193 ENSG00000112280 ENSG00000125398 ENSG00000100146 PMC11743681__F1 Cellular and Molecular mechanisms regulating Neural Crest (NC) cell migration and polarity ENSG00000064666 ENSG00000038382 ENSG00000070831 ENSG00000112655 ENSG00000121966 PMC8925056__F8 TSLP regulates mitochondrial ROS-induced mitophagy via histone modification in human monocytes ENSG00000108702 ENSG00000169245 ENSG00000102962 ENSG00000073578 ENSG00000158828 ENSG00000145777 PMC3547893__F1 Interplay between G protein-coupled receptor kinase 2 (GRK2) and histone deacetylase 6 (HDAC6) at the crossroads of epithelial cell motility ENSG00000094631 ENSG00000185591 ENSG00000171051 PMC7363821__F1 High temperature- and cortisol-induced changes in gene expression ENSG00000065833 ENSG00000100979 PMC5550896__F1 TGFB family member signaling and its target in CRC ENSG00000107779 ENSG00000121989 ENSG00000170365 ENSG00000123612 ENSG00000135503 ENSG00000204217 ENSG00000114739 PMC3710993__F1 Energy status of cells modulating cell signaling and mitochondrial function PMC8584016__F1 Systemic Review: Ozone: A Potential New Chemotherapy ENSG00000181019 ENSG00000079999 PMC3141289__F1 Signaling pathway leading to signal transducer and activator of transcription (STAT)-3 activation (see text for definitions of abbreviations) ENSG00000242689 ENSG00000163235 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC2646065__F8 Proposed model involving GSK-3 inhibition and the mTOR pathway to stimulate human Beta-cell growth and proliferation ENSG00000169047 ENSG00000198793 ENSG00000168036 PMC3923157__F2 Tumor necrosis factorA and its osteoblastogenesis paradoxical effects ENSG00000100422 ENSG00000281324 ENSG00000162337 ENSG00000167941 PMC8602361__F1 Alpha-Synuclein Induced Immune Cells Activation and Associated Therapy in Parkinson’s Disease ENSG00000162711 ENSG00000136869 PMC2819219__F7 Caspase Mediated Cleavage, IAP Binding and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NFKB Signaling ENSG00000112977 ENSG00000168040 PMC7886986__F1 Major immune cell checkpoints and associated signaling pathways ENSG00000089692 ENSG00000291603 ENSG00000117091 ENSG00000134982 ENSG00000082512 ENSG00000175104 ENSG00000127191 PMC7963908__F9 TNBS-induced activation of the toll-like receptor (TLR) 4 signal transduction signaling cascade, which leads to the activation of canonical NF-kB pathway ENSG00000136869 PMC8316766__F1 Genetic Polymorphisms Associated With the Pharmacokinetics, Pharmacodynamics and Adverse Effects of Olanzapine, Aripiprazole and Risperidone ENSG00000138115 ENSG00000275190 ENSG00000140505 ENSG00000244474 PMC5727528__F3 Metabolic interventions predicted by the OptForce algorithm ENSG00000197713 ENSG00000197429 ENSG00000131263 PMC5319818__F1 Gasotransmitters in cancer: from pathophysiology to experimental therapy PMC2572128__F1 Simplified model of translation initiation ENSG00000106682 ENSG00000163435 ENSG00000100842 ENSG00000100664 PMC8015171__F9 Basal cell-fibroblast interaction in IPF ENSG00000105329 ENSG00000198670 ENSG00000108821 PMC7247570__F3 Cross-talk of the mitogen-activated protein kinase (MAPK)/ERK signaling pathway and mechanism of cell death induction through the ERK-Hippo interplay ENSG00000171791 ENSG00000146648 ENSG00000164305 PMC6435939__F1 Proposed platelet-endothelial cell adhesion molecule-1 (PECAM1) and Src signaling pathway activation in ARDS and in ventilator-induced lung injury ENSG00000261371 ENSG00000291971 ENSG00000168610 PMC8467684__F6 Identification and Characterization of Novel circRNAs Involved in Muscle Growth of Blunt Snout Bream (Megalobrama amblycephala) ENSG00000132906 ENSG00000149089 ENSG00000002330 ENSG00000160224 ENSG00000198793 ENSG00000146648 ENSG00000164305 PMC7289300__F5 LncRNA-mRNA expression correlation network (co-expression network) analysis of core mRNAs and their correlated lncRNAs ENSG00000110711 ENSG00000136997 ENSG00000102316 ENSG00000282937 ENSG00000125743 PMC12063130__F2 Targets of JNK/p38 MAPK signaling pathway in OC drug resistance ENSG00000134057 ENSG00000135446 PMC7073664__F7 Putative fatty acid synthase pathway of Thraustochytriidae sp ENSG00000026103 PMC3328211__F2 Arterial-venous and lymphatic specification in vertebrate embryo ENSG00000196411 ENSG00000176692 ENSG00000135547 ENSG00000164736 ENSG00000285438 ENSG00000118257 ENSG00000203883 PMC3740204__F2 Angiogenesis pathway of FAK, EZH2 and Dll4/Notch in cancer-associated endothelial cells ENSG00000071246 ENSG00000112242 ENSG00000148400 ENSG00000291971 ENSG00000112715 PMC7697807__F1 Activation and negative regulation of NFKB and STAT3 ENSG00000168610 PMC12133565__F6 Loss of Hdac1 hyperactivates oncogenic transcription ENSG00000164742 ENSG00000154678 ENSG00000140044 ENSG00000112715 ENSG00000115896 ENSG00000007171 ENSG00000061938 ENSG00000008118 PMC3941008__F1 Complement activation pathways ENSG00000166278 PMC9485881__F3 Advances in the superhydrophilicity-modified titanium surfaces with antibacterial and pro-osteogenesis properties: A review ENSG00000066294 ENSG00000177575 ENSG00000125538 PMC3832913__F3 Alternative pathway ENSG00000039537 ENSG00000113600 ENSG00000000971 ENSG00000178726 ENSG00000062485 PMC8139965__F7 Hypothetical schema of the effect of IL-26 on EGFR-TKI resistance ENSG00000081041 ENSG00000128272 ENSG00000138798 ENSG00000162772 ENSG00000146648 PMC4670900__F4 The proposed pathway for energy production, based on the KEGG-associated proteins found in the proteome of L ENSG00000261701 ENSG00000073578 ENSG00000150787 PMC4606066__F1 Expression and function of the insulin/IGF system in normal and colorectal cancer cells ENSG00000197081 ENSG00000169047 ENSG00000198793 ENSG00000168036 PMC6567810__F7 Construction of a regulatory network for integrated miRNA-target genes ENSG00000106261 ENSG00000109819 ENSG00000182158 ENSG00000138336 ENSG00000084676 ENSG00000185591 ENSG00000180357 ENSG00000168610 ENSG00000080298 PMC8324686__F2 Function of the endolysosomal network in cholesterol homeostasis and metabolic-associated fatty liver disease (MAFLD) ENSG00000130164 ENSG00000169174 PMC9437888__F2 Developing a CRISPR‐assisted base‐editing system for genome engineering of Pseudomonas chlororaphis ENSG00000042832 ENSG00000115263 ENSG00000158104 PMC9204280__F10 FOXP4-AS1 May be a Potential Prognostic Biomarker in Human Cancers: A Meta−Analysis and Bioinformatics Analysis ENSG00000181163 ENSG00000131153 ENSG00000291964 ENSG00000163918 ENSG00000166508 ENSG00000112312 ENSG00000093009 ENSG00000128050 ENSG00000236826 ENSG00000101868 ENSG00000151465 ENSG00000183527 ENSG00000159055 ENSG00000130332 ENSG00000112578 ENSG00000197498 ENSG00000107833 ENSG00000071539 ENSG00000280548 ENSG00000124787 ENSG00000136982 ENSG00000130826 ENSG00000124802 ENSG00000096063 ENSG00000145604 ENSG00000110104 ENSG00000137168 ENSG00000156802 ENSG00000152455 ENSG00000149136 ENSG00000113460 ENSG00000166582 ENSG00000101003 ENSG00000126249 ENSG00000119203 ENSG00000163811 ENSG00000166965 ENSG00000133119 ENSG00000084774 ENSG00000175792 PMC8324686__F1 Function of the endolysosomal network in cholesterol homeostasis and metabolic-associated fatty liver disease (MAFLD) ENSG00000169228 ENSG00000130164 ENSG00000167461 ENSG00000119655 ENSG00000069329 ENSG00000141458 ENSG00000173456 PMC4128878__F1 Alpha-catenin ENSG00000134982 ENSG00000168036 PMC11898721__F11 QSAR-Based Drug Repurposing and RNA-Seq Metabolic Networks Highlight Treatment Opportunities for Hepatocellular Carcinoma Through Pyrimidine Starvation ENSG00000162368 ENSG00000128951 ENSG00000134326 ENSG00000138185 ENSG00000188833 ENSG00000171793 ENSG00000047230 ENSG00000102967 PMC7404279__F4 Depiction of a cancer cell motility and migration signaling network model that includes DEGs identified by RNA-seq analysis () as displaying upregulated genes in H ENSG00000070831 ENSG00000291971 ENSG00000163914 PMC11024251__F2 Signaling pathway of EGF ENSG00000110395 ENSG00000138798 ENSG00000146648 PMC9020058__F7 De novo identification of maximally deregulated subnetworks based on multi-omics data with DeRegNet ENSG00000154342 ENSG00000169427 ENSG00000175793 ENSG00000291971 ENSG00000263057 ENSG00000168036 ENSG00000164171 ENSG00000182621 ENSG00000166851 ENSG00000117399 ENSG00000139219 ENSG00000074211 ENSG00000263243 ENSG00000029559 ENSG00000118785 ENSG00000089685 ENSG00000113296 ENSG00000164362 ENSG00000188130 PMC7738817__F5 miR-133a involves in EGFR/c-Myc/P53 axis and the associated signaling pathway ENSG00000107562 ENSG00000146648 ENSG00000121966 PMC9248048__F3 Footprint of Kynurenine Pathway in Cardiovascular Diseases ENSG00000163739 ENSG00000113161 ENSG00000106546 PMC2661541__F1 Transforming growth factor-beta (TGFB) signaling pathway PMC8064165__F8 Dual activation of Hedgehog and Wnt/Beta-catenin signaling pathway caused by downregulation of SUFU targeted by miRNA-150 in human gastric cancer ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000128602 PMC3236571__F7 Resistance mechanisms in the TRAIL signaling pathway ENSG00000171791 ENSG00000168040 PMC3917155__F4 Inhibiting 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase to AMPK activation and anti-tumor activity ENSG00000198793 ENSG00000198931 ENSG00000145723 PMC7670868__F1 Outline of major DNA DSB repair pathway and its relationship with host anti-tumor immune response ENSG00000149311 ENSG00000175054 ENSG00000110721 ENSG00000123374 ENSG00000125347 PMC11020452__F4 Regulatory mechanism of tsRNAs in cancers ENSG00000134982 ENSG00000168036 ENSG00000184916 ENSG00000164916 PMC4693238__F3 Intracellular detection of viral RNA by PRRs and activation of the innate immune response ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000125538 ENSG00000160710 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC11000312__F3 Mechanisms underlying SALL4 regulation and function in colorectal cancer ENSG00000101115 ENSG00000168036 PMC6814794__F9 KEGG pathway enrichment analysis of methylated regions– ENSG00000102871 ENSG00000007908 ENSG00000168040 ENSG00000127191 ENSG00000073756 ENSG00000164305 ENSG00000157227 ENSG00000078747 ENSG00000177606 ENSG00000131323 ENSG00000168404 ENSG00000074410 ENSG00000026103 PMC11000312__F2 Mechanisms underlying SALL4 regulation and function in gastric cancer ENSG00000101115 ENSG00000145321 ENSG00000026508 ENSG00000168036 ENSG00000168610 ENSG00000159399 PMC9508095__F9 Influenza A virus use of BinCARD1 to facilitate the binding of viral NP to importin A7 is counteracted by TBK1-p62 axis-mediated autophagy ENSG00000183735 ENSG00000131323 PMC11000312__F1 Mechanisms underlying SALL4 regulation and function in esophageal cancer ENSG00000115216 ENSG00000154342 ENSG00000283780 ENSG00000148400 ENSG00000074181 ENSG00000101115 ENSG00000168036 ENSG00000143995 PMC3607645__F5 Epidermis model pathways ENSG00000143867 ENSG00000060237 PMC11000312__F4 Mechanisms underlying SALL4 regulation and function in liver cancer ENSG00000119888 ENSG00000101115 ENSG00000026508 ENSG00000171345 PMC5406704__F1 The phosphatidylinositol-3-kinase (PI3K) pathway ENSG00000198793 ENSG00000121966 PMC4053166__F1 Meet the terminator: the phosphatase PP2A puts brakes on IRF-3 activation ENSG00000094631 ENSG00000183735 PMC4891110__F8 Screening the yeast genome for energetic metabolism pathways involved in a phenotypic response to the anti-cancer agent 3-bromopyruvate ENSG00000074800 ENSG00000124253 PMC8217088__F6 Lipid metabolic alterations induced by EPHB2 deficiency in prostate cancer ENSG00000285482 ENSG00000062282 ENSG00000133216 PMC6689672__F3 Differential pathway regulation in advanced idiopathic pulmonary fibrosis (IPF) lung ENSG00000186810 ENSG00000169896 ENSG00000161921 ENSG00000170458 ENSG00000196371 ENSG00000158825 ENSG00000107485 ENSG00000121966 ENSG00000115009 ENSG00000106546 PMC4187736__F11 Model recapitulating the role played by HUWE1 in regulating Shoc2-supported ERK1/2 activity ENSG00000138798 ENSG00000086758 ENSG00000108061 PMC3896945__F1 Pharmacological approaches to restore mitochondrial function ENSG00000105835 ENSG00000198793 ENSG00000106459 PMC8983858__F2 Induction of Endothelial Autophagy and Its Role in the Development of Atherosclerosis ENSG00000261371 ENSG00000110799 ENSG00000198793 ENSG00000163914 ENSG00000127528 PMC8642070__F4 Bicuspid Aortic Valve: Genetic and Clinical Insights ENSG00000127616 ENSG00000008083 PMC9202500__F6 Functions of Viroporins in the Viral Life Cycle and Their Regulation of Host Cell Responses ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000167207 ENSG00000114030 ENSG00000147896 ENSG00000131323 ENSG00000146648 ENSG00000142166 PMC5187897__F1 Intrinsic and extrinsic apoptosis pathways in mammalian cells ENSG00000102871 ENSG00000120868 ENSG00000168040 ENSG00000026103 PMC9202500__F5 Functions of Viroporins in the Viral Life Cycle and Their Regulation of Host Cell Responses ENSG00000128272 ENSG00000100219 PMC9202500__F4 Functions of Viroporins in the Viral Life Cycle and Their Regulation of Host Cell Responses ENSG00000177169 ENSG00000198793 ENSG00000057663 ENSG00000140443 PMC4614139__F1 Mutations in PI3K, PTEN and AKT have dual effects on neuronal development leading to the formation of HMEG and FCD PMC5447936__F2 AUTS2-Rac signaling pathways in neuronal migration and neuritogenesis ENSG00000062598 ENSG00000158321 PMC4022194__F2 Signalling pathways that were altered in the high serum group ENSG00000065613 ENSG00000277909 ENSG00000165891 ENSG00000134982 ENSG00000087586 ENSG00000177519 ENSG00000126787 ENSG00000177084 ENSG00000117399 PMC9267958__F5 Pharmacological Properties of 4′, 5, 7-Trihydroxyflavone (Apigenin) and Its Impact on Cell Signaling Pathways ENSG00000138798 ENSG00000136869 PMC9267958__F4 Pharmacological Properties of 4′, 5, 7-Trihydroxyflavone (Apigenin) and Its Impact on Cell Signaling Pathways ENSG00000172936 ENSG00000136869 PMC9267958__F3 Pharmacological Properties of 4′, 5, 7-Trihydroxyflavone (Apigenin) and Its Impact on Cell Signaling Pathways ENSG00000111537 ENSG00000115415 ENSG00000291971 ENSG00000168610 PMC11654293__F8 Expression levels of differentially expressed genes related to galactose, starch and sucrose metabolism ENSG00000257335 ENSG00000118094 PMC6742699__F2 Complement-platelet interactions that can facilitate an inflammatory response that favors atheroma formation ENSG00000110799 ENSG00000244731 ENSG00000163737 PMC4062840__F2 Regulation of Akt phosphorylation ENSG00000081913 ENSG00000040199 PMC11050257__F3 Representation of the diversity of the AP-1 family of TF ENSG00000070831 ENSG00000156127 ENSG00000149269 ENSG00000081189 PMC9375713__F2 NLRP12 in Innate Immunity and Inflammation ENSG00000088888 ENSG00000125538 ENSG00000142405 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000121060 ENSG00000184216 ENSG00000164342 PMC9556725__F1 Neurobiology of pain and facial movements in rodents: Clinical applications and current research ENSG00000196689 PMC11050257__F5 MYC protein and its signaling pathway ENSG00000134982 ENSG00000136997 PMC7390965__F1 Differences between the UPR in mammalian and plant cells ENSG00000144895 ENSG00000100219 PMC3136489__F7 Pathways Activated during Human Asthma Exacerbation as Revealed by Gene Expression Patterns in Blood ENSG00000117228 ENSG00000187608 ENSG00000183486 ENSG00000157601 ENSG00000033800 ENSG00000115267 ENSG00000185745 ENSG00000185885 ENSG00000216490 ENSG00000125347 ENSG00000230034 ENSG00000172183 ENSG00000138378 ENSG00000111537 ENSG00000115415 ENSG00000185201 ENSG00000186803 PMC11050257__F2 Androgen receptor structure and signaling pathway in PCa ENSG00000129214 ENSG00000184012 PMC10570508__F2 PITX1 acts as a core gene that regulates the p53 signaling pathway ENSG00000127445 ENSG00000168066 ENSG00000198176 PMC8224422__F2 Synthetic Formatotrophs for One‐Carbon Biorefinery ENSG00000180210 ENSG00000226275 ENSG00000069482 ENSG00000084110 ENSG00000167701 PMC9065266__F3 Inflammasomes in Cancer Progression and Anti-Tumor Immunity ENSG00000278718 ENSG00000162711 ENSG00000111537 ENSG00000163568 ENSG00000174885 ENSG00000091106 ENSG00000147697 ENSG00000026103 PMC3294376__F4 O-linked N-acetylglucosamine (O-GlcNAc) is a nutrient sensor and underlies glucose toxicity ENSG00000147162 ENSG00000198408 ENSG00000169047 ENSG00000185591 ENSG00000182621 ENSG00000160741 PMC9065266__F2 Inflammasomes in Cancer Progression and Anti-Tumor Immunity ENSG00000162711 ENSG00000090402 ENSG00000163568 ENSG00000174885 ENSG00000091592 ENSG00000145777 ENSG00000091106 PMC9065266__F1 Inflammasomes in Cancer Progression and Anti-Tumor Immunity ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000174885 ENSG00000091592 ENSG00000274571 ENSG00000091106 ENSG00000276068 ENSG00000273992 ENSG00000143815 ENSG00000125538 ENSG00000142405 ENSG00000172936 ENSG00000185792 PMC5594744__F3 The MUST complex (MAGEL2-USP7-TRIM27) is important for the retromer-mediated endosomal protein recycling pathway ENSG00000069329 PMC4020352__F1 Noncanonical transforming growth factor B signaling in scleroderma fibrosis ENSG00000170365 ENSG00000291971 PMC4020352__F3 Noncanonical transforming growth factor B signaling in scleroderma fibrosis PMC9243368__F1 Advancements in prevention and intervention of sensorineural hearing loss ENSG00000168036 ENSG00000273529 ENSG00000184916 ENSG00000114315 ENSG00000172238 PMC3671705__F1 Targeted therapies for head and neck cancer ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC10224264__F3 Hypothesized mechanism of coronavirus-induced neuronal damage via oxidative stress and mitochondria dysfunction ENSG00000130234 ENSG00000125538 ENSG00000184012 PMC11922887__F1 Potential mechanisms of HDAC1 and HDAC2 in microglial activation and/or neuropathic pain ENSG00000041982 ENSG00000171720 ENSG00000196591 ENSG00000172936 ENSG00000136869 ENSG00000185591 PMC5960217__F1 Schematic depiction of the canonical and non-canonical Wnt pathways ENSG00000154342 ENSG00000070831 ENSG00000134982 ENSG00000168036 ENSG00000125084 PMC4340386__F1 Simplified diagram of the sphingolipid biosynthesis pathway in S ENSG00000159263 ENSG00000112246 ENSG00000229314 PMC5979467__F2 Role of survivin in caspase-mediated apoptosis ENSG00000002330 ENSG00000168040 ENSG00000062485 ENSG00000026103 PMC5979467__F3 Survivin regulation ENSG00000198793 ENSG00000168036 ENSG00000146648 ENSG00000140443 ENSG00000062485 PMC5405063__F1 Regulation of translation initiation by the (TOR) pathway, eIF4E activity and eIF2A phosphorylation in response to developmental and environmental cues in plants ENSG00000089154 ENSG00000144895 PMC12180219__S1 Bionic bearing-inspired lubricating microspheres characterized by immunomodulatory for osteoarthritis treatment ENSG00000125398 ENSG00000149968 ENSG00000157766 ENSG00000100985 ENSG00000122194 ENSG00000158859 PMC3814599__F1 The nuclear pore complex (NPC) and classical nuclear import pathway ENSG00000047410 ENSG00000111581 ENSG00000099901 ENSG00000124789 ENSG00000030066 ENSG00000126883 ENSG00000132182 ENSG00000113569 ENSG00000110713 ENSG00000125450 ENSG00000069248 ENSG00000213024 ENSG00000132341 PMC8143540__F2 Oxidative Stress in Cancer Cell Metabolism ENSG00000002330 ENSG00000291971 ENSG00000198793 PMC11922887__F3 Potential mechanisms of Sirt1 in microglial activation and/or neuropathic pain ENSG00000162711 ENSG00000198576 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000164690 ENSG00000096717 PMC8291349__F4 Regulation of the CYP7A1 gene ENSG00000019991 ENSG00000160867 ENSG00000167910 ENSG00000125538 ENSG00000117707 ENSG00000096717 ENSG00000197063 PMC11922887__F2 Potential mechanisms of HDAC3 in microglial activation and/or neuropathic pain ENSG00000164430 ENSG00000171720 ENSG00000115415 ENSG00000163568 ENSG00000096717 PMC10224264__F5 Anti-apoptotic and anti-inflammatory effects of Ginkgo biloba extract (EGb) and its constituents ENSG00000115415 ENSG00000168610 PMC8291349__F1 Bile acid and oxysterol synthesis in the liver and other tissues ENSG00000276559 ENSG00000167910 ENSG00000036530 ENSG00000180432 ENSG00000115271 ENSG00000135929 PMC7538629__F5 Changes of FAs metabolism in hamster liver of HFD group (A) and HFD+ADT group (B) ENSG00000135218 ENSG00000134824 ENSG00000149485 ENSG00000171109 ENSG00000026103 PMC6514289__F1 Metabolic pathway of vicagrel and clopidogrel in humans ENSG00000172831 ENSG00000114771 ENSG00000165841 ENSG00000197408 ENSG00000140505 PMC8143540__F3 Oxidative Stress in Cancer Cell Metabolism ENSG00000002330 ENSG00000168040 ENSG00000127191 PMC4261550__F1 Neuroprotective functions of resveratrol in AD pathogenesis ENSG00000115415 ENSG00000086991 ENSG00000168610 PMC4951507__F4 ICL repair ENSG00000012048 ENSG00000175054 ENSG00000144554 ENSG00000188827 ENSG00000187790 ENSG00000051180 ENSG00000139618 ENSG00000276043 PMC10994423__F5 Advances in the application of traditional Chinese medicine during the COVID-19 recovery period: A review ENSG00000111145 ENSG00000137275 ENSG00000115415 ENSG00000157625 ENSG00000127191 PMC4951507__F3 Main posttranslational modification events involved in the activation of response to ICLs ENSG00000149311 ENSG00000175054 ENSG00000112701 ENSG00000063978 ENSG00000144554 ENSG00000077152 ENSG00000033800 ENSG00000115392 ENSG00000162607 PMC6523687__F1 Epidermal growth factor receptor (EGFR)/EGFR variant III (EGFRvIII)-dependent biological signaling pathways ENSG00000198793 ENSG00000146648 PMC7346972__F1 Insulin growth factor pathway and its relationship to intracellular signaling molecules ENSG00000002330 ENSG00000198793 ENSG00000140443 PMC6376270__F5 Interleukin‐1B (IL‐1B) was up‐regulated in nerve regeneration ENSG00000081041 ENSG00000102871 ENSG00000138798 ENSG00000099860 ENSG00000150787 ENSG00000150455 ENSG00000073756 ENSG00000010671 ENSG00000095585 ENSG00000149311 ENSG00000100290 ENSG00000226275 ENSG00000213658 ENSG00000170458 ENSG00000186716 ENSG00000125538 ENSG00000136869 ENSG00000172936 ENSG00000121060 ENSG00000141655 PMC5960217__F3 Wnt signaling in hematopoietic stem cells and early B cell development ENSG00000272398 ENSG00000188763 PMC7348145__F8 WDFY3‐AS2 contributes to the suppression of cell proliferation and invasion by manipulating miR‐2355‐5p/SOCS2 signalling axis ENSG00000120833 PMC5960217__F4 Wnt signaling pathway and multiple myeloma ENSG00000162552 ENSG00000026508 ENSG00000168036 ENSG00000002745 PMC2694829__F6 HIV-1 TAT T cell receptor signaling pathway ENSG00000213658 PMC9300700__F4 Broad view of the role of Galectin-3 in microglia-associated neurodegenerative diseases ENSG00000162711 ENSG00000153208 ENSG00000172243 ENSG00000129226 ENSG00000136869 ENSG00000136235 PMC4990112__F3 RNF8 and RNF168 promote the accumulation of 53BP1 and RAP80 at DSB sites ENSG00000188486 ENSG00000185513 ENSG00000012048 ENSG00000163961 ENSG00000150991 ENSG00000174429 ENSG00000112130 PMC7687355__F4 Predicted activation of VEGF signaling after both APAP300 and PHX ENSG00000072571 ENSG00000167772 ENSG00000187048 ENSG00000171476 ENSG00000164109 ENSG00000178999 ENSG00000069122 ENSG00000076003 ENSG00000144476 ENSG00000112312 PMC4990112__F2 BRCA1 promotes DNA end resection, but the BRCA1-A complex suppresses excessive DNA end resection ENSG00000012048 ENSG00000083093 ENSG00000139618 PMC7687355__F3 Predicted activation of HGF signaling after both APAP300 and PHX ENSG00000072571 ENSG00000019991 ENSG00000069122 ENSG00000131910 ENSG00000071539 ENSG00000144476 ENSG00000125968 ENSG00000112312 PMC7687355__F6 Temporal differences in activation of IL6 signaling after APAP300 and PHX ENSG00000172216 ENSG00000127954 ENSG00000146678 ENSG00000221869 ENSG00000168610 ENSG00000146648 ENSG00000028137 ENSG00000124762 PMC3517178__F2 Polyploid cells rewire DNA damage response networks to overcome replication stress-induced barriers for tumour progression ENSG00000117724 ENSG00000087245 ENSG00000132646 ENSG00000125538 ENSG00000121966 ENSG00000069667 PMC2781439__F7 Speculative model depicting mono-ubiquitination-dependent and independent functions of the FA-BRCA pathway in DNA replication-associated repair processes ENSG00000175054 ENSG00000144554 ENSG00000077152 ENSG00000132646 ENSG00000162607 ENSG00000070950 PMC5118428__F7 K-state regulation in domesticated and undomesticated strains ENSG00000198894 ENSG00000125656 PMC12247361__F2 miR-1303 regulates cancer progression through targeting multiple genes across distinct cancer types ENSG00000050165 ENSG00000137076 ENSG00000104332 PMC9576687__F3 Premature senescence induced by ischemia/reperfusion injury ENSG00000135446 ENSG00000105810 PMC9576687__F2 Cellular senescence signaling pathways ENSG00000149311 ENSG00000175054 ENSG00000136997 PMC3909012__F7 Cell Surface Area and Membrane Folding in Glioblastoma Cell Lines Differing in PTEN and p53 Status ENSG00000198793 ENSG00000026103 PMC11898961__F1 Simplified 5-ALA metabolic pathway ENSG00000066926 ENSG00000115657 PMC3875676__F4 High-throughput screen identifies disulfiram as a potential therapeutic for triple-negative breast cancer cells ENSG00000130413 ENSG00000136997 ENSG00000146648 PMC11931053__F8 Huoshan Dendrobium Zengye Jiedu Formula mitigates radiation-induced oral mucositis and improves oral immune microenvironment by targeting the EGFR/PI3K/AKT pathway: evidence from network pharmacology, molecular docking, and experimental validation ENSG00000138798 ENSG00000146648 PMC7687355__F8 Predicted activation of EGF and PDGF signaling after APAP300 compared to PHX at 24 hr ENSG00000128016 ENSG00000143878 ENSG00000138798 ENSG00000122877 ENSG00000124766 ENSG00000175592 ENSG00000162772 ENSG00000178726 ENSG00000177426 ENSG00000157557 ENSG00000134057 ENSG00000136997 ENSG00000171848 ENSG00000152518 PMC8403340__F3 Glutamate-mediated, calcium-related signaling in glioma progression ENSG00000198793 ENSG00000148408 ENSG00000198838 ENSG00000291874 ENSG00000119782 ENSG00000132535 ENSG00000163873 ENSG00000171189 ENSG00000081248 ENSG00000006283 ENSG00000100345 ENSG00000106436 ENSG00000198626 ENSG00000143933 ENSG00000107736 ENSG00000198363 ENSG00000221823 ENSG00000156564 ENSG00000176884 ENSG00000125675 ENSG00000067191 ENSG00000108878 ENSG00000080845 ENSG00000291649 ENSG00000115155 ENSG00000291651 ENSG00000101608 PMC6807343__F8 Proposed model ENSG00000125538 ENSG00000169047 PMC6073120__F4 Endocytic trafficking of PAR1 ENSG00000185236 ENSG00000113369 ENSG00000103769 ENSG00000028528 PMC6393786__F2 Optogenetic switches ENSG00000132341 PMC4932542__F1 Models that have been proposed to explain the inhibition of tumor cell proliferation by metformin PMC5341926__F3 Proteomic analysis uncovers common effects of IFNG and IL-27 on the HLA class I antigen presentation machinery in human cancer cells ENSG00000228716 ENSG00000175054 ENSG00000067066 ENSG00000134982 ENSG00000177606 ENSG00000124275 ENSG00000111331 ENSG00000132963 PMC9367541__F2 Mutations Affecting Genes in the Proximal T-Cell Receptor Signaling Pathway in Peripheral T-Cell Lymphoma ENSG00000113263 PMC9367541__F1 Mutations Affecting Genes in the Proximal T-Cell Receptor Signaling Pathway in Peripheral T-Cell Lymphoma ENSG00000291603 ENSG00000070831 ENSG00000010810 ENSG00000198793 ENSG00000115904 ENSG00000113263 ENSG00000124181 ENSG00000141968 ENSG00000198286 PMC11799259__F2 Interaction between genes/pathways in prostate cancer (A) Rb deletion promotes the expression of genes downstream of the AR pathway through transcriptional activation of E2F and facilitating promoter recruitment of the AR ENSG00000136997 PMC4542378__F10 Activated signaling pathways that regulate KSHV lytic replication during primary infection ENSG00000142627 ENSG00000120899 ENSG00000291971 PMC4046911__F2 PI3K-AKT signaling is a downstream effector of retinoid prevention of murine basal cell carcinogenesis ENSG00000165030 ENSG00000176046 ENSG00000099860 ENSG00000120437 ENSG00000283060 PMC3466406__F7 Biological insights obtained by combining logical modeling and experimental data ENSG00000019991 ENSG00000135446 ENSG00000138798 ENSG00000105810 PMC4516713__F6 Brain signaling network reprogramming in response to mild mitochondrial uncoupling ENSG00000128272 ENSG00000118515 ENSG00000198576 ENSG00000140443 PMC9267148__F6 Prediction of CIAPIN1 (Cytokine-Induced Apoptosis Inhibitor 1) Signaling Pathway and Its Role in Cholangiocarcinoma Metastasis ENSG00000167601 ENSG00000135317 ENSG00000249709 ENSG00000033327 ENSG00000111783 ENSG00000167515 ENSG00000101266 ENSG00000196628 ENSG00000135776 ENSG00000140548 ENSG00000152926 ENSG00000108821 ENSG00000169218 ENSG00000114346 ENSG00000189056 ENSG00000221869 ENSG00000076555 ENSG00000160973 ENSG00000187510 ENSG00000040199 ENSG00000122705 ENSG00000080603 ENSG00000139154 ENSG00000119862 ENSG00000166037 PMC9313271__F1 Current Concepts of Vitiligo Immunopathogenesis ENSG00000169245 ENSG00000186810 ENSG00000138755 PMC10937991__F8 Graphical abstract ENSG00000159128 ENSG00000111537 PMC9267148__F7 Prediction of CIAPIN1 (Cytokine-Induced Apoptosis Inhibitor 1) Signaling Pathway and Its Role in Cholangiocarcinoma Metastasis ENSG00000005194 ENSG00000136603 ENSG00000148498 ENSG00000160973 ENSG00000157933 ENSG00000157077 ENSG00000065361 ENSG00000102981 ENSG00000101266 ENSG00000160691 PMC8514585__F2 PRMT5 in DNA damage response in prostate cancer ENSG00000012048 ENSG00000185379 ENSG00000051180 ENSG00000187736 ENSG00000139618 ENSG00000175792 ENSG00000111247 PMC3877845__F1 mTOR signalling pathway ENSG00000100811 ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC2808051__F20 Reversible phosphorylation regulation of the cell cycle ENSG00000149311 ENSG00000282899 PMC9008451__F2 Interleukin-22 in Renal Protection and Its Pathological Role in Kidney Diseases ENSG00000169245 ENSG00000162711 ENSG00000108691 ENSG00000002330 ENSG00000136869 ENSG00000168610 ENSG00000106546 PMC6396373__F9 Herpesviral antagonist m152 reveals differential activation of STING‐dependent IRF and NF‐KB signaling and STING's dual role during MCMV infection ENSG00000183735 ENSG00000164430 PMC8615124__F3 Mitochondrial Redox Metabolism: The Epicenter of Metabolism during Cancer Progression PMC8144889__F3 Regulatory control of the Na–Cl co-transporter NCC and its therapeutic potential for hypertension ENSG00000143867 ENSG00000060237 ENSG00000146021 PMC8144889__F2 Regulatory control of the Na–Cl co-transporter NCC and its therapeutic potential for hypertension ENSG00000152266 ENSG00000126562 ENSG00000143867 ENSG00000060237 ENSG00000118515 ENSG00000146021 PMC3466406__F2 The integrated large-scale logical model ENSG00000019991 ENSG00000112576 ENSG00000174989 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000149308 ENSG00000073111 ENSG00000118971 ENSG00000107829 ENSG00000175054 ENSG00000245848 ENSG00000172216 ENSG00000136997 ENSG00000152592 ENSG00000123374 ENSG00000185591 ENSG00000105810 ENSG00000067900 ENSG00000168610 ENSG00000081189 ENSG00000149311 ENSG00000145604 ENSG00000094804 ENSG00000135446 ENSG00000177606 ENSG00000132646 ENSG00000146648 PMC5239799__F1 Integration of non-genomic signaling and canonical signaling of androgen receptor (AR) ENSG00000002330 ENSG00000291971 PMC3801191__F1 Estrogen Regulation of Dkk1 and Wnt/Beta-Catenin Signaling in Neurodegenerative Disease ENSG00000134982 PMC6284793__F8 Known and novel BP associations in the TGFB signalling pathway ENSG00000121989 ENSG00000157933 ENSG00000133937 ENSG00000105329 ENSG00000115297 ENSG00000183072 ENSG00000156574 ENSG00000020633 ENSG00000276561 ENSG00000160973 ENSG00000198742 ENSG00000164093 ENSG00000126458 PMC5920792__F2 Feedback Regulation of RTK Signaling in Development ENSG00000198793 ENSG00000062485 PMC7203229__F3 Genomic competition for noise reduction shaped evolutionary landscape of mir-4673 ENSG00000071564 ENSG00000087510 ENSG00000008196 ENSG00000137203 ENSG00000214285 ENSG00000168036 ENSG00000196628 ENSG00000102974 PMC6543531__F8 Regulated Necrosis and Failed Repair in Cisplatin-Induced Chronic Kidney Disease ENSG00000148346 ENSG00000164938 ENSG00000065320 ENSG00000115718 ENSG00000158445 ENSG00000124762 ENSG00000133216 PMC4888836__F1 Model for the noncanonical HDR pathways at two-ended DSBs ENSG00000012061 ENSG00000051180 ENSG00000177084 PMC6657303__F4 Mitochondrial and Endoplasmic Reticulum Reactive Oxygen Species Production in Models of Perinatal Brain Injury ENSG00000162711 ENSG00000128272 ENSG00000144895 ENSG00000171791 ENSG00000079999 PMC6557692__F1 Pro-Inflammatory Cytokine Activation of NFKB in Synovial Fibroblasts ENSG00000173039 ENSG00000168040 PMC10377498__F5 Mitophagy: A Bridge Linking HMGB1 and Parkinson’s Disease Using Adult Zebrafish as a Model Organism ENSG00000189403 ENSG00000136869 ENSG00000214253 PMC3798933__F2 Insulin signaling pathways are inhibited by damage-associated molecular pattern (DAMP)-mediated, Toll-like receptor (TLR)-mediated pathways ENSG00000174125 ENSG00000124102 ENSG00000169047 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 PMC6299398__F5 Affected pathways in group 4 medulloblastoma ENSG00000106571 ENSG00000244694 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC9496697__F1 GSK3 Is a Central Player in Retinal Degenerative Diseases but a Challenging Therapeutic Target ENSG00000168036 ENSG00000162924 ENSG00000127948 PMC8365026__F1 Endoplasmic Reticulum Stress in Cerebral Ischemia ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC6299398__F3 Consequences of driver gene mutations in canonical Wnt signaling ENSG00000169047 ENSG00000168036 ENSG00000121879 ENSG00000109670 PMC6299398__F2 Affected pathways in SHH-activated medulloblastoma ENSG00000106571 ENSG00000100387 ENSG00000197102 ENSG00000113558 ENSG00000128602 PMC3469602__F4 Serum and Antibodies of Glaucoma Patients Lead to Changes in the Proteome, Especially Cell Regulatory Proteins, in Retinal Cells ENSG00000084774 ENSG00000115317 ENSG00000026103 PMC11055311__F1 Main signaling pathways involved in TPL in cancer ENSG00000156076 ENSG00000281324 ENSG00000164736 ENSG00000120057 ENSG00000173039 ENSG00000123374 ENSG00000134644 ENSG00000100985 ENSG00000168610 ENSG00000157240 PMC4994294__F4 Unigenes involved in the plant hormone signal transduction pathway in SAM of Oriental hybrid lily ENSG00000110934 ENSG00000221818 PMC4124034__F3 Translational Control by Heme-Regulated eIF2A Kinase during Erythropoiesis ENSG00000128272 ENSG00000144895 PMC9503257__F6 Intestinal microbiome-mediated resistance against vibriosis for Cynoglossus semilaevis ENSG00000174125 ENSG00000183735 ENSG00000161533 ENSG00000131323 ENSG00000276561 ENSG00000164342 ENSG00000135929 PMC5286530__F1 FGFR signaling pathway ENSG00000070388 ENSG00000070193 ENSG00000115415 ENSG00000105550 ENSG00000140285 ENSG00000167900 ENSG00000168610 PMC7701218__F9 Proposed CCN3-mediated signaling pathways in placental diseases PE and AIP ENSG00000148400 ENSG00000135446 ENSG00000123374 PMC11928779__F8 A‐KG and tRNA deoxygenation in the cytosol and mitochondria ENSG00000178694 ENSG00000037474 ENSG00000068438 PMC4036111__F3 Schematic of the FGFR signaling pathway ENSG00000077782 PMC3616322__F2 Signalling regulation of mammalian autophagy ENSG00000169047 PMC10530385__F1 Tet1 regulates pathways responding to PM2.5-induced oxidative stress ENSG00000181019 ENSG00000137033 ENSG00000109321 ENSG00000163235 ENSG00000125538 ENSG00000100219 ENSG00000127191 ENSG00000140465 ENSG00000146648 ENSG00000106546 ENSG00000079999 PMC8365026__F3 Endoplasmic Reticulum Stress in Cerebral Ischemia ENSG00000144895 ENSG00000127191 PMC7377944__F2 Human telomerase in homeostasis and disease ENSG00000100836 ENSG00000164362 ENSG00000114127 ENSG00000137574 ENSG00000172795 PMC8645129__F8 Development and characterization of efficient xylose utilization strains of Zymomonas mobilis ENSG00000084093 ENSG00000104237 ENSG00000178573 PMC7643412__F4 Crosstalk between ferroptosis and apoptosis, necroptosis, autophagy-dependent cell death and pyroptosis ENSG00000115884 ENSG00000151012 ENSG00000137275 ENSG00000167468 ENSG00000120868 ENSG00000168404 ENSG00000285379 ENSG00000128965 PMC7643412__F3 Published molecular mechanisms of ferroptosis in breast cancer ENSG00000147649 ENSG00000128272 ENSG00000151012 ENSG00000144895 ENSG00000137275 ENSG00000291971 ENSG00000167468 ENSG00000168404 ENSG00000168610 ENSG00000285379 ENSG00000128965 PMC11928134__F7 HPS1 and ITK function in melanocyte and T-Cell ENSG00000107521 ENSG00000113263 PMC7643412__F1 Ferroptosis pathways ENSG00000163930 ENSG00000197635 ENSG00000167468 ENSG00000197429 ENSG00000113161 ENSG00000111684 ENSG00000079999 PMC7730978__F1 Gain of function (GOF) effect of mutant p53 and regulation of autophagy by p53 in nucleus ENSG00000127445 ENSG00000198793 ENSG00000140464 PMC6752729__F1 Summary of molecular basis on which epigallocatechin-3-gallate (EGCG) prevents chronic kidney disease (CKD) and renal fibrosis based on preclinical evidence ENSG00000162711 ENSG00000181019 ENSG00000170558 ENSG00000168036 ENSG00000005381 PMC11928779__F5 MTOR signaling network ENSG00000155792 ENSG00000179632 ENSG00000167965 ENSG00000239282 PMC5676564__F1 Representative signalling pathway of human TLRs in the cell membrane (TLR1/2, TLR2/6, TLR4, TLR5, and TLR10) and endosome (TLR3, TLR4, TLR7, and TLR9) ENSG00000174123 ENSG00000183735 ENSG00000239732 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000276561 ENSG00000164342 PMC6433747__F1 Androgenic-inducible miRNAs involved in the process of BC progression ENSG00000124766 ENSG00000026508 PMC11927577__F3 KEGG signaling pathway analysis of up-DEGs and down-DEGs in AD ENSG00000103811 ENSG00000177595 ENSG00000108669 ENSG00000163131 ENSG00000196743 ENSG00000061676 ENSG00000136068 PMC8774449__F1 Serum Vitamin D as a Biomarker in Autoimmune, Psychiatric and Neurodegenerative Diseases ENSG00000172893 ENSG00000019186 ENSG00000186104 PMC7738566__F3 Enhancer effects in establishing cancer signaling environments ENSG00000121989 ENSG00000109452 ENSG00000112576 ENSG00000157404 ENSG00000149930 ENSG00000141551 ENSG00000160551 ENSG00000135090 ENSG00000134982 ENSG00000196782 ENSG00000164327 ENSG00000141564 ENSG00000124762 ENSG00000183765 ENSG00000122025 ENSG00000065717 ENSG00000187957 ENSG00000143801 ENSG00000073614 ENSG00000155011 ENSG00000136997 ENSG00000123933 ENSG00000108375 ENSG00000174197 ENSG00000196498 ENSG00000116990 ENSG00000105810 ENSG00000165323 ENSG00000077782 ENSG00000139687 ENSG00000140443 ENSG00000196712 ENSG00000109670 ENSG00000113645 ENSG00000134376 ENSG00000166341 ENSG00000101109 ENSG00000156076 ENSG00000292149 ENSG00000105568 ENSG00000106829 ENSG00000197070 ENSG00000110395 ENSG00000065526 ENSG00000146648 ENSG00000178568 ENSG00000198793 ENSG00000115904 ENSG00000168036 ENSG00000169032 ENSG00000047936 ENSG00000104332 ENSG00000118971 ENSG00000179295 ENSG00000083857 ENSG00000070444 ENSG00000186575 ENSG00000120057 ENSG00000104371 ENSG00000183579 ENSG00000143622 ENSG00000123374 ENSG00000108788 ENSG00000135503 ENSG00000281178 ENSG00000005339 ENSG00000157764 ENSG00000065361 ENSG00000114978 ENSG00000106483 ENSG00000184916 ENSG00000131023 ENSG00000074219 ENSG00000079999 ENSG00000149311 ENSG00000066468 ENSG00000160867 ENSG00000135446 ENSG00000148204 ENSG00000050165 ENSG00000134853 ENSG00000213347 ENSG00000168646 ENSG00000114166 ENSG00000198625 PMC8152475__F9 Multi-Functional MPT Protein as a Therapeutic Agent against Mycobacterium tuberculosis ENSG00000183735 ENSG00000159399 PMC9339490__F2 Glioma-neuronal interactions in tumor progression: Mechanism, therapeutic strategies and perspectives (Review) ENSG00000149968 ENSG00000291971 ENSG00000100985 ENSG00000137845 PMC5798144__F6 Egulation of actin cytoskeleton pathway and the differentially expressed genes on the bare and the TiN-coated NiTi alloys ENSG00000180210 ENSG00000069482 ENSG00000070831 ENSG00000134982 ENSG00000138443 ENSG00000163914 ENSG00000089159 PMC5798144__F4 TGFB signaling pathway and the differentially expressed genes in both the bare and the TiN-coated NiTi alloy groups ENSG00000049323 ENSG00000111537 ENSG00000095739 ENSG00000100387 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000185591 ENSG00000164093 ENSG00000205250 ENSG00000111816 PMC9610432__F4 Foot-and-Mouth Disease Virus: Molecular Interplays with IFN Response and the Importance of the Model PMC9610432__F3 Foot-and-Mouth Disease Virus: Molecular Interplays with IFN Response and the Importance of the Model ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000170458 ENSG00000135341 ENSG00000121060 PMC523881__F1 The monolignol biosynthetic pathway ENSG00000102977 ENSG00000084774 PMC10454457__F3 Constitutively expressed genes of class I and II major histocompatibility complex processes of endogenous and exogenous antigen processing pathways found in chicken thrombocytes ENSG00000019582 ENSG00000232326 ENSG00000127022 ENSG00000273686 ENSG00000231925 PMC10454457__F2 Genes of the TLR signaling pathway observed in chicken thrombocytes ENSG00000174125 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC11871217__F7 Deduced signaling pathways regulated by LvMmd2 ENSG00000002330 ENSG00000136297 ENSG00000163291 ENSG00000131023 PMC11705844__F7 The mechanism by which BMAL1 deficiency impairs cognitive function ENSG00000142192 ENSG00000109321 ENSG00000146648 PMC9118424__F6 Transcriptome and Metabolome Analysis of the Synthesis Pathways of Allelochemicals in Eupatorium adenophorum ENSG00000160752 ENSG00000167508 PMC9464914__F1 Pinocytotic engulfment of lipoproteins by macrophages ENSG00000117020 ENSG00000070831 ENSG00000163510 ENSG00000136869 ENSG00000075239 PMC9160457__F9 Attenuation effect of potassium 2‐(1‐hydroxypentyl)‐benzoate in a mouse model of diabetes‐associated cognitive decline: The protein expression in the brain ENSG00000102385 ENSG00000163539 ENSG00000063854 ENSG00000116586 ENSG00000198793 ENSG00000169567 PMC6435963__F1 Complement activation cascades and functions ENSG00000009724 ENSG00000291559 ENSG00000244731 PMC3930409__F10 Epidermal growth factor (EGF-EGFR) signalling pathway in hepatocellular carcinoma (HCC) inflammatory microenvironment ENSG00000138798 ENSG00000169429 ENSG00000146648 PMC3901225__F2 Protein complexes and their connection with metabolism ENSG00000101751 ENSG00000150787 PMC6435963__F2 Regulation of complement activation by RCAs or parasite-expressed proteins targeting different complement components at the different steps of complement activation ENSG00000291559 ENSG00000203710 PMC6600670__F8 Mechanism by which EPD attenuates IMQ-induced psoriasis by inhibiting the inflammation responses via TLR7/8–MyD88–NFKB–NLRP3 inflammasome signaling pathways ENSG00000162711 ENSG00000172936 ENSG00000175104 PMC8306788__F1 Hippo Signaling Pathway as a New Potential Target in Non-Melanoma Skin Cancers: A Narrative Review ENSG00000150457 ENSG00000131023 PMC4025940__F1 Roles of TGFB in the tumour microenvironment ENSG00000198793 PMC2874439__F3 Schematic representing the significant changes in gene expression in the lung of Keap1Δ2–3/Δ2–3;CctCre+ mice compared with Keap1flox/flox mice ENSG00000103222 ENSG00000176153 ENSG00000023909 ENSG00000138356 ENSG00000156273 PMC7122036__F1 Transforming growth factor B (TGFB) signaling in aortic aneurysms and dissections (AAD) PMC8229934__F5 Sildenafil Counteracts the In Vitro Activation of CXCL-9, CXCL-10 and CXCL-11/CXCR3 Axis Induced by Reactive Oxygen Species in Scleroderma Fibroblasts ENSG00000169248 ENSG00000169245 ENSG00000186810 ENSG00000115415 ENSG00000138755 PMC3328609__F3 Development of the Bile Ducts: Essentials for the Clinical Hepatologist ENSG00000134982 ENSG00000168036 PMC11505293__F4 Polycystic Ovary Syndrome and Ferroptosis: Following Ariadne’s Thread ENSG00000171195 ENSG00000197635 ENSG00000116044 ENSG00000109320 ENSG00000135365 ENSG00000072274 ENSG00000105697 ENSG00000158828 ENSG00000142082 ENSG00000149311 ENSG00000138336 ENSG00000167468 ENSG00000187855 ENSG00000135503 ENSG00000110911 PMC5372284__F4 Phospho-sites identified in proteins of the RAS-RAF-MAPK and PI3K-AKT signaling pathway in a lung adenocarcinoma cell line harboring a L858R mutation in the kinase domain of EGFR, which is reactive to treatment with erlotinib ENSG00000138798 ENSG00000141564 PMC11505293__F2 Updated PCOS network: network depicting the associations (connecting lines) of PCOS-relevant genes/gene products (nodes) ENSG00000116731 ENSG00000135451 ENSG00000135365 ENSG00000109906 ENSG00000072274 ENSG00000111615 ENSG00000147124 ENSG00000171791 ENSG00000115970 ENSG00000143379 ENSG00000204843 ENSG00000169429 ENSG00000136869 ENSG00000104899 ENSG00000292286 ENSG00000197635 ENSG00000105697 ENSG00000158828 ENSG00000170498 ENSG00000158169 ENSG00000278270 ENSG00000125347 ENSG00000138336 ENSG00000130385 ENSG00000150672 ENSG00000115263 ENSG00000167468 ENSG00000103460 ENSG00000178568 ENSG00000130726 ENSG00000101367 ENSG00000153094 ENSG00000142330 ENSG00000150093 ENSG00000146833 ENSG00000068438 ENSG00000142082 ENSG00000179295 ENSG00000121903 ENSG00000130164 ENSG00000129214 ENSG00000130234 ENSG00000004487 ENSG00000125538 ENSG00000182255 ENSG00000112578 ENSG00000121853 ENSG00000135503 ENSG00000167701 ENSG00000116014 ENSG00000171195 ENSG00000115008 ENSG00000151012 ENSG00000116044 ENSG00000285109 ENSG00000109320 ENSG00000109163 ENSG00000135409 ENSG00000152804 ENSG00000187855 ENSG00000110911 PMC7865768__F4 Domain structure of SPAK and the phosphorylation target sites on NKCC1 and KCC3 ENSG00000196632 ENSG00000143867 PMC7462086__F2 SOS1 Gain of Function Variants in Dilated Cardiomyopathy ENSG00000019991 ENSG00000157764 ENSG00000115904 ENSG00000169032 ENSG00000062485 PMC1456930__F5 The molecular pathways controlling AB generation during aging ENSG00000140443 PMC3163738__F3 IFNA (type-I IFN) and IFN-λ (type-III IFN) signal through distinct receptor complexes, but activate the same intracellular signaling pathway ENSG00000105397 ENSG00000115415 ENSG00000157601 ENSG00000147896 ENSG00000276561 ENSG00000142166 PMC10222048__F3 KEGG pathway analysis of glycolysis and gluconeogenesis ENSG00000074800 ENSG00000278373 ENSG00000135678 ENSG00000131828 ENSG00000169299 ENSG00000006534 PMC8446806__F1 Complement cascade in the regulation of neuroinflammation, nociceptive sensitization, and pain ENSG00000039537 ENSG00000113600 ENSG00000134830 ENSG00000291559 ENSG00000288512 ENSG00000203710 ENSG00000197405 ENSG00000166278 ENSG00000117322 ENSG00000182326 ENSG00000236625 PMC3956809__F4 Tissue-specific expression within individual functions—a case of insulin signaling pathway ENSG00000130957 ENSG00000163558 ENSG00000162409 ENSG00000198793 ENSG00000169710 ENSG00000235194 ENSG00000078098 ENSG00000102974 PMC6786387__F11 Proposed model illustrating the mechanism that underlies NTZ in the amelioration of AD pathology ENSG00000181019 ENSG00000198793 PMC12210724__F1 Association of SNPs in carbohydrate metabolism genes with insulin resistance indicators in the Mexican population ENSG00000130957 ENSG00000067992 ENSG00000059804 ENSG00000073578 ENSG00000117118 ENSG00000288174 ENSG00000163541 ENSG00000197496 ENSG00000173262 ENSG00000197241 ENSG00000100191 ENSG00000162426 ENSG00000281165 ENSG00000074800 ENSG00000100412 ENSG00000173599 ENSG00000100170 ENSG00000146701 ENSG00000091140 ENSG00000062485 ENSG00000109667 ENSG00000125166 ENSG00000197713 ENSG00000160883 ENSG00000067057 ENSG00000108515 ENSG00000005882 ENSG00000153574 ENSG00000105953 ENSG00000172340 ENSG00000117834 ENSG00000131828 ENSG00000101365 ENSG00000143252 ENSG00000163114 ENSG00000172840 ENSG00000110435 ENSG00000164708 ENSG00000124253 ENSG00000136872 ENSG00000159399 PMC6993488__F3 Inhibiting T cell activity causes anti-PD-1/PD-L1 immunotherapy resistance PMC5235905__F9 LPS/TLR4 engagement promotes AMPK dephosphorylation and decreased kinase activity in peritoneal macrophages ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC7096153__F2 Ingenuity Pathway Analysis ENSG00000157764 ENSG00000134308 ENSG00000164082 ENSG00000198626 ENSG00000152402 ENSG00000182621 ENSG00000119383 ENSG00000081189 ENSG00000187980 ENSG00000169967 ENSG00000007168 ENSG00000164742 ENSG00000117020 ENSG00000125675 ENSG00000166501 ENSG00000291761 ENSG00000115419 ENSG00000177425 PMC5338169__F2 The endothelial cell and monocyte in early stages of atherosclerosis: potential mechanisms of milk derived bioactive peptides ENSG00000135218 ENSG00000136869 ENSG00000121807 PMC9033766__F6 Sphingosine-1-phosphate hinders the osteogenic differentiation of dental pulp stem cells in association with AKT signaling pathways ENSG00000108821 PMC5524345__F9 Dkk3 gene encodes a vital intracellular regulator of cell proliferation ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8632642__F8 Co-Exposure of Cardiomyocytes to IFNG and TNFA Induces Mitochondrial Dysfunction and Nitro-Oxidative Stress: Implications for the Pathogenesis of Chronic Chagas Disease Cardiomyopathy ENSG00000115415 ENSG00000096717 ENSG00000007171 PMC8594130__F6 Knockdown of long noncoding RNA GAS5 reduces vascular smooth muscle cell apoptosis by inactivating EZH2-mediated RIG-I signaling pathway in abdominal aortic aneurysm ENSG00000183735 PMC8234993__F4 Molecular Human Targets of Bioactive Alkaloid-Type Compounds from Tabernaemontana cymose Jacq. ENSG00000177455 ENSG00000149089 ENSG00000103479 ENSG00000002330 ENSG00000179091 ENSG00000186716 PMC8204019__F4 Radiation Resistance: A Matter of Transcription Factors ENSG00000181019 ENSG00000148400 ENSG00000167468 ENSG00000114315 ENSG00000146648 ENSG00000079999 PMC8204019__F3 Radiation Resistance: A Matter of Transcription Factors ENSG00000149311 ENSG00000134057 PMC9564311__F5 Potential Fatty Acid Metabolism-Related Gene Signature for Prognosis in Clear Cell Renal Cell Carcinoma ENSG00000157184 ENSG00000108515 ENSG00000072210 ENSG00000080819 ENSG00000115361 ENSG00000164120 PMC11853788__F4 Proposed regulatory network involving relevant metabolic pathways in Longissimus dorsi muscle (LDM) after composite plant extracts (CPE) addition ENSG00000188089 ENSG00000117215 ENSG00000141086 ENSG00000173599 PMC2981398__F1 Role of the N-end rule pathway in RGS protein degradation ENSG00000182901 ENSG00000135824 ENSG00000143248 ENSG00000150681 ENSG00000148908 ENSG00000090104 ENSG00000157045 ENSG00000091844 ENSG00000117152 ENSG00000116741 ENSG00000107669 ENSG00000127074 PMC7256023__F1 TGFBeta-induced epithelial-to-mesenchymal transition ENSG00000169554 ENSG00000124216 ENSG00000122691 ENSG00000170558 ENSG00000163914 ENSG00000288335 PMC4105632__F1 Nigrostriatal, mesocortical, and mesolimbic pathways ENSG00000157005 PMC4405749__F6 Resveratrol protects against doxorubicin-induced cardiotoxicity in aged hearts through the SIRT1-USP7 axis ENSG00000150907 ENSG00000096717 PMC6129280__F5 piMGM: incorporating multi-source priors in mixed graphical models for learning disease networks ENSG00000124102 ENSG00000117020 ENSG00000185386 ENSG00000188130 ENSG00000121879 ENSG00000171608 ENSG00000131196 PMC8284093__F7 Genomic Response to TGFB1 Dictates Failed Repair and Progression of Fibrotic Disease in the Obstructed Kidney ENSG00000170365 ENSG00000126016 ENSG00000134982 ENSG00000081051 ENSG00000132849 ENSG00000168646 ENSG00000169435 PMC9201920__F3 Non-Coding RNAs as Novel Regulators of Neuroinflammation in Alzheimer’s Disease ENSG00000125538 ENSG00000172936 PMC7256023__F5 Lipid and choline metabolism in TGFBeta-induced EMT ENSG00000131473 ENSG00000110721 ENSG00000124216 ENSG00000137673 ENSG00000136535 ENSG00000169710 ENSG00000102172 PMC7256023__F3 TCA cycle is active in TGFBeta-induced EMT ENSG00000143252 ENSG00000073578 ENSG00000117118 PMC8069677__F4 Effect and regulation of the NLRP3 inflammasome during fibrosis ENSG00000162711 ENSG00000125538 ENSG00000086991 ENSG00000136869 PMC6314405__F1 Immunological pathways targeted by the main novel therapies for IBD ENSG00000099866 ENSG00000105656 PMC11907837__F2 Wnt/Beta-catenin-related ncRNAs that regulate tumour cell proliferation, metastasis and invasion ENSG00000141867 ENSG00000134982 ENSG00000168036 ENSG00000126003 ENSG00000189299 ENSG00000101558 PMC11907837__F1 Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11052502__F4 Results of PPI, KEGG, Reactome, and GO analysis of 19 common proteins that were targets of 1-MNA and RA-associated gene targets ENSG00000143799 ENSG00000126218 ENSG00000140992 ENSG00000171105 ENSG00000149968 ENSG00000123374 ENSG00000100985 ENSG00000113448 PMC4794722__F2 Kcne2 deletion causes early-onset nonalcoholic fatty liver disease via iron deficiency anemia ENSG00000214456 ENSG00000171503 ENSG00000107798 ENSG00000197746 ENSG00000131910 ENSG00000109819 ENSG00000157184 ENSG00000159197 ENSG00000117054 ENSG00000187048 ENSG00000083720 ENSG00000122971 ENSG00000105379 PMC5223024__F1 TLR and the related TNFR and IL-1R signaling pathways ENSG00000170458 ENSG00000102871 ENSG00000125538 ENSG00000173039 ENSG00000172936 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000127191 PMC7560924__F5 Resistance and response to insulin by mTORC1 PMC3787928__F2 Action of Smac mimetics.Notes: IAPs are important regulators of NFKB-activating signaling pathways ENSG00000104856 ENSG00000102871 ENSG00000173039 ENSG00000168040 ENSG00000127191 ENSG00000102172 PMC3418637__F1 Context-dependent effect of PI3K signaling on Treg development, differentiation and maintenance ENSG00000049768 PMC8670233__F2 Elastin Structure, Synthesis, Regulatory Mechanism and Relationship With Cardiovascular Diseases PMC8527296__F1 Putative type I interferonopathy genotypes ENSG00000187608 ENSG00000122218 ENSG00000089127 ENSG00000197785 ENSG00000230034 ENSG00000151092 ENSG00000142166 ENSG00000101868 ENSG00000173369 ENSG00000138035 ENSG00000177409 ENSG00000164430 ENSG00000197594 ENSG00000093072 ENSG00000026297 ENSG00000104889 ENSG00000155858 ENSG00000172922 ENSG00000205220 ENSG00000159189 ENSG00000184979 ENSG00000149311 ENSG00000105612 ENSG00000173372 ENSG00000115415 ENSG00000197299 ENSG00000132963 PMC2394659__F3 Aged Retinal Pigment Epithelium/Choroid: A Potential Substratum for the Pathogenesis of Age-Related Macular Degeneration ENSG00000292348 ENSG00000026508 ENSG00000154721 ENSG00000100365 ENSG00000089159 ENSG00000154096 PMC9139716__F3 Brain Organization and Human Diseases ENSG00000170365 ENSG00000138083 ENSG00000183691 ENSG00000156574 ENSG00000164690 ENSG00000128602 ENSG00000077782 PMC317355__F3 Wnt-signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000167074 PMC10520073__F7 Graphical representation of the regulation mechanism underlying ABC variant rs4810856 and CRC risk ENSG00000124126 PMC9030470__F3 Epigenetic Regulation of Chondrocytes and Subchondral Bone in Osteoarthritis ENSG00000281766 ENSG00000198901 ENSG00000151376 ENSG00000162521 PMC6959099__F2 Metabolic changes associated with innate immune responses in lung disease ENSG00000137033 ENSG00000145777 ENSG00000026103 PMC2409816__F1 Schematic representation of the major pathways of ganglioside biosynthesis ENSG00000069482 ENSG00000111728 PMC5372671__F1 Mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway ENSG00000155792 ENSG00000288461 ENSG00000196712 PMC6959099__F1 Catabolic and anabolic metabolism in the cell ENSG00000081181 PMC4387288__F2 BCL6 targets Tfh genes mainly involved in T cell signaling, differentiation, and migration pathways to drive the GC Tfh phenotype ENSG00000134460 ENSG00000198793 ENSG00000027697 ENSG00000127528 ENSG00000049768 ENSG00000168610 ENSG00000069667 ENSG00000162594 ENSG00000100385 ENSG00000138378 ENSG00000111537 ENSG00000115415 ENSG00000107485 ENSG00000126353 ENSG00000073861 ENSG00000112486 ENSG00000115594 PMC3101870__F1 Three levels of regulation of the IGF-IR pathwayand its components ENSG00000002330 ENSG00000197081 ENSG00000291972 ENSG00000198793 ENSG00000140443 PMC4335252__F10 Molecular mechanism of attenuation of the PI3K/Akt signaling pathway by gingipains ENSG00000002330 ENSG00000198793 PMC3145576__F5 Pathway analysis of proteins detected at elevated concentrations during time course analysis in lung following intratracheal instillation of 20 μg carbon nanoparticles (CNP) ENSG00000102962 ENSG00000110799 ENSG00000057593 ENSG00000125538 ENSG00000113520 PMC3266776__F2 Understanding pRb: toward the necessary development of targeted treatments for retinoblastoma ENSG00000145604 ENSG00000120868 ENSG00000282899 PMC6014593__F2 Summary schematic of eye morphogenesis pathways ENSG00000038382 ENSG00000197713 ENSG00000070831 PMC5138592__F5 Identification of critical paralog groups with indispensable roles in the regulation of signaling flow ENSG00000138795 ENSG00000110492 ENSG00000148400 ENSG00000132478 ENSG00000100060 ENSG00000184916 ENSG00000137845 ENSG00000135144 ENSG00000090932 ENSG00000110042 ENSG00000106003 ENSG00000128917 ENSG00000078747 PMC7789255__F2 Possible paracrine mechanisms controlling differentiation of spermatogonia in adult testis ENSG00000121207 ENSG00000138207 ENSG00000003137 ENSG00000121039 ENSG00000143320 ENSG00000146857 ENSG00000188425 ENSG00000120669 PMC7789255__F1 Possible paracrine mechanisms controlling self-renewal of spermatogonia in juvenile testis ENSG00000095596 ENSG00000187553 ENSG00000121207 ENSG00000003137 ENSG00000121039 ENSG00000165643 ENSG00000143320 ENSG00000109906 ENSG00000285007 ENSG00000187772 ENSG00000120669 PMC5883534__F4 BRAF kinase inhibitor resistance and alternative activation of MAPK targets and pigmentation ENSG00000019991 ENSG00000142627 ENSG00000104044 ENSG00000120693 ENSG00000107175 ENSG00000099617 ENSG00000145431 ENSG00000164742 ENSG00000134853 ENSG00000136160 ENSG00000080166 ENSG00000077782 ENSG00000101333 ENSG00000158050 PMC4439419__F1 Cell cycle arrest in senescent cells ENSG00000134982 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC2633067__F2A Beyond Good and Evil in the Oral Cavity: Insights into Host-Microbe Relationships Derived from Transcriptional Profiling of Gingival Cells ENSG00000180210 ENSG00000134982 ENSG00000138443 ENSG00000163914 ENSG00000135905 ENSG00000089159 PMC3982775__F1 Structure of the systems model of type C4 photosynthesis ENSG00000261701 ENSG00000159224 ENSG00000172005 ENSG00000115271 PMC4051248__F9 LPS up-regulates the PhT2 signaling pathway ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC7509264__F1 Resolution of inflammation in immune and nonimmune cells by interleukin-19 ENSG00000168610 ENSG00000174564 ENSG00000142224 ENSG00000016402 PMC3191051__F9 Model for TGFB1-mediated signaling to the miR143/145 regulatory region ENSG00000105329 ENSG00000141052 PMC3257565__F2 HSC cell cycle entry is regulated by a complex network of cell-intrinsic and cell-extrinsic factors ENSG00000168283 ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 ENSG00000114315 PMC8291015__F1 Impact of the COVID-19 pandemic on inflammatory bowel disease patients: A review of the current evidence ENSG00000130234 ENSG00000184012 PMC3405739__F2 The processes included in the insulin model ENSG00000124102 PMC8114202__F5 Thyrotrophin and thyroxine support immune homeostasis in humans ENSG00000239732 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC3007169__F1 Arsenic: a potentially useful poison for Hedgehog-driven cancers ENSG00000128602 PMC9379413__F3 Phase separation in Cancer: From the Impacts and Mechanisms to Treatment potentials ENSG00000141867 ENSG00000134982 ENSG00000125686 ENSG00000168036 ENSG00000131023 ENSG00000165617 PMC4101819__F1 Key signaling pathways involved in genetic methylation of lymphoid malignancies ENSG00000134982 ENSG00000168036 PMC8453085__F5 Th17 Cells in Periodontitis and Its Regulation by A20 ENSG00000278718 ENSG00000162711 ENSG00000137275 PMC5759028__F8 KRAS/TGFB/p15Ink4b pathway controls the cell fate ENSG00000105329 ENSG00000139687 PMC3736320__F1 Déjà vu: EGF receptors drive resistance to BRAF inhibitors ENSG00000019991 ENSG00000138798 ENSG00000140443 PMC6520855__F2 Targeting the Hedgehog pathway ENSG00000141867 ENSG00000166813 ENSG00000128602 ENSG00000105204 PMC6520855__F1 Hedgehog pathway in absence (a) and in presence (b) of HH ligand ENSG00000157540 ENSG00000106571 ENSG00000166813 ENSG00000166851 ENSG00000128602 ENSG00000127334 PMC6751615__F5 Possible pathways for the synthesis of bioactive stress mediators from the arachidonic acid (AA) cascade in the immune tissues of chickens PMC9395317__F4 Cytokine‐ and chemokine‐induced inflammatory colorectal tumor microenvironment: Emerging avenue for targeted therapy ENSG00000019991 ENSG00000107562 ENSG00000134982 ENSG00000291971 ENSG00000005882 ENSG00000138798 ENSG00000170558 ENSG00000168036 ENSG00000168610 ENSG00000121966 ENSG00000150782 ENSG00000108691 ENSG00000100985 PMC7900639__F2 Drug induced ER stress response regulation in trypanosomes: (a) Elevated expression of Sirtuins in ER stress might activate autophagy by deacetylating ATG proteins, and sirtuins regulate subsequent switch to apoptosis at a higher stress level ENSG00000144895 ENSG00000120686 ENSG00000081307 ENSG00000057663 PMC6992650__F5 Kaposi sarcoma-associated herpesvirus infection pathway from KEGG ENSG00000261857 ENSG00000149308 ENSG00000111816 PMC8268416__F1 Plant responses to geminivirus infection: guardians of the plant immunity ENSG00000171189 ENSG00000066629 ENSG00000057663 PMC1937548__F4 Comparison of nonsynonymous substitution rates among members of RB and p53 signaling pathways ENSG00000135446 ENSG00000105810 PMC5835320__F7 Canonical pathway analysis for genes determining cellular responsiveness to As2O3 using Ingenuity Pathway Analysis ENSG00000167693 ENSG00000183723 ENSG00000138772 ENSG00000178999 ENSG00000184363 ENSG00000138071 ENSG00000151693 ENSG00000141934 ENSG00000065833 ENSG00000099995 ENSG00000116221 ENSG00000119397 ENSG00000198838 ENSG00000292170 ENSG00000163914 ENSG00000136997 ENSG00000146678 ENSG00000162521 ENSG00000115271 ENSG00000168310 ENSG00000112182 ENSG00000124664 ENSG00000125968 ENSG00000101290 ENSG00000099204 ENSG00000109320 ENSG00000213390 ENSG00000137310 ENSG00000108582 ENSG00000144366 ENSG00000115884 ENSG00000126698 ENSG00000068120 ENSG00000146648 ENSG00000023839 PMC5835320__F6 Network pharmacology for genes determining cellular responsiveness to As2O3 using Ingenuity Pathway Analysis ENSG00000167693 ENSG00000183723 ENSG00000138772 ENSG00000120756 ENSG00000178999 ENSG00000166260 ENSG00000184363 ENSG00000146143 ENSG00000138071 ENSG00000099995 ENSG00000116221 ENSG00000119397 ENSG00000198838 ENSG00000136997 ENSG00000138162 ENSG00000146678 ENSG00000162521 ENSG00000160808 ENSG00000115271 ENSG00000168310 ENSG00000112182 ENSG00000124664 ENSG00000125968 ENSG00000099204 ENSG00000109320 ENSG00000213390 ENSG00000137310 ENSG00000108582 ENSG00000114126 ENSG00000068120 PMC6912660__F1 The main estrogen receptors signaling pathways: in the genomic pathway, classic estrogen receptors (ER A and B) act as transcription factors upon homo- or heterodimers ENSG00000157764 ENSG00000138798 ENSG00000115904 PMC3390969__F2 Impact of a negative regulator on pathogenesis and the development of sepsis, secondary to acute insults ENSG00000177575 ENSG00000170458 ENSG00000172936 ENSG00000175104 PMC9513370__F3 Crosstalk between dendritic cells and regulatory T cells: Protective effect and therapeutic potential in multiple sclerosis ENSG00000049768 ENSG00000106546 PMC9513370__F2 Crosstalk between dendritic cells and regulatory T cells: Protective effect and therapeutic potential in multiple sclerosis ENSG00000089692 ENSG00000145777 ENSG00000049768 PMC4887024__F5 Feed Efficiency within a Pedigree Male Broiler Line: I. Highlight on Mitochondria ENSG00000166794 ENSG00000171105 ENSG00000116044 ENSG00000156482 ENSG00000164327 ENSG00000163631 ENSG00000122367 ENSG00000143761 ENSG00000175166 ENSG00000197958 ENSG00000198838 ENSG00000171759 ENSG00000138777 ENSG00000119912 ENSG00000173692 ENSG00000116761 ENSG00000152556 ENSG00000143632 PMC10239456__F3 Interaction graph and dynamic behavior of the PanNETs Boolean model ENSG00000145604 ENSG00000133895 ENSG00000139515 ENSG00000136997 PMC7022928__F1 Retinoic acid signaling pathway ENSG00000121207 ENSG00000138207 ENSG00000143320 PMC2908393__F5 Apolipoprotein E and its receptors in Alzheimer’s disease: pathways, pathogenesis and therapy ENSG00000130164 PMC5275772__F4 Beneficial effects of hepatic CAV‐1 on atherosclerosis protection in DKO mice ENSG00000130164 ENSG00000042832 ENSG00000135929 ENSG00000026103 PMC5854367__F1 Most of Theileria parva proteins involved in glycolysis and tricarboxylic acid cycles were identified in this study ENSG00000173599 ENSG00000105953 PMC2908393__F4 Apolipoprotein E and its receptors in Alzheimer’s disease: pathways, pathogenesis and therapy ENSG00000130164 ENSG00000119912 PMC2908393__F3 Apolipoprotein E and its receptors in Alzheimer’s disease: pathways, pathogenesis and therapy ENSG00000168702 PMC4845657__F7 Nuclear factor KB1/RelA mediates inflammation in human lung epithelial cells at atmospheric oxygen levels ENSG00000109320 ENSG00000173039 PMC9647533__F7 MicroRNA-16 inhibits the TLR4/NFKB pathway and maintains tight junction integrity in irritable bowel syndrome with diarrhea ENSG00000125538 ENSG00000136869 PMC9684507__F6 rs28714259 risk (A) allele dysregulates genes following dexamethasone/doxorubicin combination treatment and contributes to an attenuated hypertrophy signaling ENSG00000147202 ENSG00000179598 ENSG00000163914 ENSG00000187840 ENSG00000140443 PMC6750724__F5 Proposed biosynthetic pathway of pepticinnamin E ENSG00000087250 ENSG00000166278 ENSG00000078674 PMC8225795__F3 Comparison of genetic alterations of signaling pathways in AFPGC and TCGA-GC ENSG00000065361 ENSG00000198793 ENSG00000137193 ENSG00000169032 ENSG00000112715 ENSG00000139618 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000066468 ENSG00000135446 ENSG00000136997 ENSG00000105810 ENSG00000077782 ENSG00000139687 ENSG00000146648 ENSG00000178568 ENSG00000196712 PMC10034899__F1 Sirtuins in attenuating plaque vulnerability in atherosclerosis ENSG00000162711 ENSG00000189403 PMC3730813__F2 Pattern Recognition Receptors in Intestinal Inflammation ENSG00000167207 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000106100 ENSG00000164342 PMC10486880__F4 Anti-cancer mechanisms of leeks and their active compounds ENSG00000198793 ENSG00000057663 PMC3730813__F1 Pattern Recognition Receptors in Intestinal Inflammation ENSG00000162711 ENSG00000125538 ENSG00000091106 PMC4996775__F9 Alpha-synuclein modulates retinal iron homeostasis by facilitating the uptake of transferrin-bound iron: Implications for visual manifestations of Parkinson’s disease ENSG00000197713 PMC9309601__F2 Cytokine storm: behind the scenes of the collateral circulation after acute myocardial infarction ENSG00000124102 ENSG00000170365 ENSG00000108691 ENSG00000139567 ENSG00000125538 ENSG00000121807 PMC6316710__F1 NCOA4-mediated ferritinophagy pathway is regulated by intracellular iron ENSG00000121058 ENSG00000167996 PMC9289867__F4 Salvia miltiorrhiza polysaccharides alleviates florfenicol-induced liver metabolic disorder in chicks by regulating drug and amino acid metabolic signaling pathways PMC5859839__F11 Pathway of compound-known target-ER-positive breast cancer network (blue circle stands for compound target; red diamond stands for pathway; green hexagon stands for herb) ENSG00000090402 ENSG00000138798 ENSG00000198793 ENSG00000171791 ENSG00000149968 ENSG00000128052 ENSG00000136997 ENSG00000125538 ENSG00000166501 ENSG00000113520 ENSG00000087245 ENSG00000104365 ENSG00000171105 ENSG00000081041 ENSG00000100906 ENSG00000173039 ENSG00000007908 ENSG00000213341 ENSG00000125347 ENSG00000073756 ENSG00000007171 ENSG00000108691 ENSG00000111537 ENSG00000118785 ENSG00000102245 ENSG00000177606 ENSG00000096717 ENSG00000159399 PMC8141035__F5 The actions of Pirh2 and KLHDC10 in mammalian RQC ENSG00000128607 ENSG00000163516 ENSG00000187024 ENSG00000165525 PMC8786145__F2 Renal Sensing of Bacterial Metabolites in the Gut-kidney Axis ENSG00000198793 PMC8650627__F8 Prediction of the Molecular Mechanisms Underlying Erlong Zuoci Treatment of Age-Related Hearing Loss via Network Pharmacology-Based Analyses Combined with Experimental Validation ENSG00000142192 ENSG00000188822 ENSG00000050628 ENSG00000291971 ENSG00000164082 ENSG00000112715 ENSG00000073756 ENSG00000007171 ENSG00000149295 ENSG00000132170 ENSG00000179295 ENSG00000112038 ENSG00000276825 ENSG00000150782 ENSG00000115415 ENSG00000149968 ENSG00000173599 ENSG00000177606 ENSG00000180616 ENSG00000146648 ENSG00000062485 PMC3893527__F4 Signal pathways involved in renal IRI ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC4314580__F2 Signaling pathways in T/NK-cell proliferation ENSG00000102871 ENSG00000082512 ENSG00000056558 ENSG00000168036 ENSG00000131323 ENSG00000127191 PMC3004747__F1 Fucose is on the TRAIL of colon cancer ENSG00000138798 ENSG00000101346 ENSG00000186866 PMC4314580__F4 Treatment strategies for inactivating EBV infection or EBV-associated oncogenic pathways ENSG00000186716 PMC7767644__F1 Autophagy is mediated by multiple signaling pathways that creating an interaction network system ENSG00000177169 ENSG00000198793 PMC6588588__F2 T cells are differentiated into multiple T cell subtypes including Th1, Th2, T-fh, Th17 and T-reg cells ENSG00000138378 ENSG00000115415 ENSG00000107485 ENSG00000049768 ENSG00000073861 PMC1133795__F3 Functions of NFKB1 and NFKB2 in immune cell biology ENSG00000104856 ENSG00000226275 ENSG00000173039 PMC11431580__F2 Schematic presentation of the interaction between estrogen receptor (ER) and the PI3K/AKT/mTOR pathway ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000173846 ENSG00000105810 PMC6140770__F9 Regulation of AMPK signaling in DM1 muscle ENSG00000152601 ENSG00000096717 PMC11431580__F4 PI3K (phosphatidylinositide 3-kinases)/PTEN (phosphatase and tensin homolog gene)/Akt pathway ENSG00000198793 PMC8998487__F3 SUMO E3 Ligases in Signaling Pathway of Cancer Cells ENSG00000188827 ENSG00000288335 ENSG00000140464 PMC7396583__F8 Model illustrating potential regulation mechanism of membrane lipid metabolism in peanut cold tolerance ENSG00000173599 ENSG00000161533 ENSG00000285482 ENSG00000198670 ENSG00000186281 PMC5938282__F5 Unique genetic cassettes in a Thermoanaerobacterium contribute to simultaneous conversion of cellulose and monosugars into butanol ENSG00000074800 ENSG00000285395 ENSG00000150787 PMC4208312__F1 B-cell receptor (BCR) and its downstream pathways ENSG00000177455 ENSG00000095585 ENSG00000167601 ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000198793 ENSG00000197943 ENSG00000010671 PMC120784__F8 Outline of the cell integrity pathway ENSG00000149489 PMC6235217__F2 Pathway analysis within the identified metabolites in the (a) tocilizumab plus methotrexate, (b) tocilizumab, and (c) methotrexate strategy arms ENSG00000172292 ENSG00000173599 ENSG00000198670 PMC7755393__F10 Oxidant quenching cycle drives the proton leak in MS-275-treated adipocytes ENSG00000157184 ENSG00000117054 ENSG00000115361 ENSG00000122971 ENSG00000126432 ENSG00000127884 PMC4208312__F4 Multiple event model for B-cell lymphomagenesis ENSG00000177455 ENSG00000095585 ENSG00000167601 ENSG00000186716 ENSG00000198793 ENSG00000197943 ENSG00000010671 ENSG00000198286 PMC9647636__F10 Crosstalk between TBK1/IKKE and the type I interferon pathway contributes to tubulointerstitial inflammation and kidney tubular injury ENSG00000183735 ENSG00000105397 ENSG00000115415 ENSG00000136869 PMC11854110__F2 Action of circRNAs participated in the chemotherapy resistance of cancer ENSG00000065978 ENSG00000168036 ENSG00000134245 ENSG00000168610 PMC7318814__F6 Summary of mechanisms of action underlying MEMP HT in BC cells PMC9686736__F4 Targeting Mitochondrial Metabolism to Reverse Radioresistance: An Alternative to Glucose Metabolism ENSG00000149311 ENSG00000168610 ENSG00000138385 PMC8867251__F7 Inhibition of the VEGF signaling pathway attenuates tumor-associated macrophage activity in liver cancer ENSG00000198793 PMC9386506__F6 Microsatellite DNA-derived oligodeoxynucleotide attenuates lipopolysaccharide-induced acute lung injury in mice by inhibiting the HMGB1-TLR4-NFKB signaling pathway ENSG00000189403 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC6425874__F3 Protein networks around RXFP2 (red) ENSG00000114450 ENSG00000133105 ENSG00000173080 ENSG00000288269 ENSG00000078369 ENSG00000107014 ENSG00000288474 ENSG00000248099 ENSG00000010310 ENSG00000115263 ENSG00000166073 ENSG00000277069 ENSG00000126895 ENSG00000179921 PMC10932966__F1 Two Sphks play different roles ENSG00000162711 ENSG00000063176 ENSG00000168610 PMC7472175__F1 Schematic model for T-cell receptor signaling ENSG00000213658 ENSG00000186834 PMC10932966__F3 Distribution of S1P is strictly controlled and involved in innate and adaptive immunity ENSG00000134982 ENSG00000183018 PMC6591247__F8 FOXP1-induced CLRN1-AS1 suppressed pituitary prolactinoma by acting as a ceRNA to regulate DKK1/Wnt/Beta-catenin pathway PMC7287590__F3 Canonical aryl hydrocarbon receptor (AhR) activation pathway ENSG00000110711 ENSG00000106546 PMC7287590__F4 Proposed models of NLRP3 inflammasome inhibition via AhR pathway ENSG00000162711 ENSG00000125538 ENSG00000106546 PMC11872079__F8 Schematic model illustrates the role of Sirtuin 5 (SIRT5) in the regulation of follicular recruitment in chickens through its influence on the autophagy-lysosome pathway in granulosa cells (GCs) ENSG00000180210 ENSG00000117525 ENSG00000124523 ENSG00000198734 PMC3754142__F3 Oncogenic and antiapoptotic functions of KSHV ENSG00000145604 ENSG00000149311 ENSG00000135446 PMC5738879__F9 Signaling pathway in the adhesion of stem cells to bone biomaterials ENSG00000136457 ENSG00000291971 ENSG00000149269 PMC9099768__F1 Obesity as a Risk Factor for Dementia and Alzheimer’s Disease: The Role of Leptin ENSG00000198793 ENSG00000168610 PMC5431132__F2 Endoplasmic reticulum‐associated degradation (ERAD) and unfolded protein responses (UPR) ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC9128097__F1 Rhythm disturbance in osteoarthritis ENSG00000154736 ENSG00000105835 ENSG00000105516 ENSG00000139219 ENSG00000170365 ENSG00000041982 ENSG00000125398 ENSG00000157227 ENSG00000157766 ENSG00000125538 ENSG00000132326 ENSG00000179094 ENSG00000096717 PMC8524703__F1 Glioblastoma pharmacotherapy: A multifaceted perspective of conventional and emerging treatments (Review) ENSG00000135446 ENSG00000198793 ENSG00000134853 ENSG00000283059 ENSG00000105810 ENSG00000146648 ENSG00000139687 ENSG00000196712 ENSG00000198625 PMC7549271__F1 Brain Penetrable Inhibitors of Ceramide Galactosyltransferase for the Treatment of Lysosomal Storage Disorders ENSG00000174607 PMC5261002__F2 Gene network associated with ‘cell death and survival, DNA replication, recombination, and repair' in sPIF-treated EVT ENSG00000099954 ENSG00000030582 ENSG00000111537 ENSG00000125735 ENSG00000156574 ENSG00000171791 ENSG00000157212 ENSG00000161714 PMC12240642__F1 Ubiquitination‐mediated degradation of EGFR‐EGF complex and inhibition of downstream signalling in EGFR‐mutated cancer ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC3235907__F1 Clopidogrel activation and platelet aggregation pathways ENSG00000180210 ENSG00000110799 ENSG00000181104 ENSG00000140505 PMC2575400__F2 MiRNA Signature of Prion Induced Neurodegeneration ENSG00000183283 ENSG00000102753 ENSG00000153037 ENSG00000132388 ENSG00000100219 ENSG00000170035 ENSG00000164305 PMC4072629__F3 VPA Alleviates Neurological Deficits and Restores Gene Expression in a Mouse Model of Rett Syndrome ENSG00000160551 ENSG00000165030 ENSG00000134215 ENSG00000138964 ENSG00000018236 ENSG00000099365 ENSG00000170469 ENSG00000101333 ENSG00000111262 ENSG00000101180 ENSG00000177301 ENSG00000134871 ENSG00000164120 ENSG00000084453 ENSG00000129159 ENSG00000151276 ENSG00000145604 ENSG00000001630 ENSG00000197959 ENSG00000101188 ENSG00000291631 ENSG00000188611 ENSG00000136160 ENSG00000139190 ENSG00000145349 ENSG00000182253 PMC9477374__F6 EA activated EPO mediated Src signaling pathway and VEGF signaling pathway to promote angiogenesis in CIRI rat brain tissue ENSG00000291971 ENSG00000187266 PMC3660836__F6 O-GlcNAcylation in FGF signaling ENSG00000147162 ENSG00000198408 PMC4249544__F3 Central carbon metabolism, including glycolysis, the pentose phosphate pathway, and the tricarboxylic acid cycle ENSG00000122966 ENSG00000172005 PMC4866030__F1 NFKB signaling pathway with genes associated with objective PNMS ENSG00000104856 ENSG00000163235 ENSG00000138798 ENSG00000173039 ENSG00000197943 ENSG00000172936 ENSG00000157625 ENSG00000150455 ENSG00000198286 PMC7312833__F6 Functional relationship between GFAP+ (glial fibrillary acidic protein) reactive astrocytes and IBA+ (ionized calcium-binding adapter molecule) activated microglia ENSG00000169245 ENSG00000148346 ENSG00000186810 ENSG00000189403 ENSG00000136869 ENSG00000131095 PMC7312833__F5 Chemokine signaling pathway ENSG00000169245 ENSG00000148346 ENSG00000186810 ENSG00000108691 ENSG00000259207 ENSG00000131095 ENSG00000121807 ENSG00000168610 PMC7312833__F2 Canonical and non-canonical inflammasome pathways ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC7312833__F1 Toll-like receptors (TLRs) signaling pathway ENSG00000183735 ENSG00000125538 ENSG00000189403 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000115594 ENSG00000164342 PMC4586772__F1 Inhibitors have been developed for their ability to block Hh signaling at various signaling nodes in the pathway ENSG00000128602 PMC7312833__F4 Interleukin (IL)-6/Grp130-JAK-STAT signaling pathway ENSG00000168610 PMC7312833__F3 Tumor necrosis factor A (TNFA)/TNFR1 signaling pathway ENSG00000137275 ENSG00000125538 ENSG00000127191 PMC4702912__F6 ‘Wnt Signaling pathway’ from KEGG () (ID hsa04310) ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000100592 ENSG00000095739 ENSG00000100387 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000168036 ENSG00000196470 PMC6966455__F8 Signaling pathway involved in GR cells with ROCK2 inhibition ENSG00000185591 PMC3612035__F7 Non-Canonical CRL4A/4BCDT2 Interacts with RAD18 to Modulate Post Replication Repair and Cell Survival ENSG00000149311 ENSG00000175054 ENSG00000167513 ENSG00000132646 ENSG00000070950 PMC4127377__F9 MAF mediates crosstalk between Ras-MAPK and mTOR signaling in NF1 ENSG00000125398 ENSG00000178573 ENSG00000155792 PMC5576693__F4 Study on molecular mechanism of ANOS1 promoting development of colorectal cancer ENSG00000011201 ENSG00000164932 ENSG00000138795 ENSG00000169071 ENSG00000155011 ENSG00000106483 ENSG00000104332 ENSG00000165617 ENSG00000157240 PMC7682230__F3 Hypoxia signaling pathway involves EGLN1-mediated hydroxylation and VHL-dependent ubiquitination of HIF-1A/2A subunits leading to its proteosomal degrardation under normoxic conditions ENSG00000134086 ENSG00000185591 PMC6235775__F4 Intracellular calcium regulates muscle atrophy via calpain regulated Ub-proteasome pathway and apoptosis PMC3712188__F3 Autophagy and polyglutamine diseases ENSG00000181467 ENSG00000171791 PMC3712188__F2 Inducing autophagy by inhibiting the mTOR pathway.mTOR is a downstream effector of the class I phosphoinositol 3-kinase (PI3K) pathway ENSG00000177169 ENSG00000167965 PMC3966871__F3 High-Throughput Quantitative Proteomic Analysis of Dengue Virus Type 2 Infected A549 Cells ENSG00000167601 ENSG00000175866 ENSG00000134851 ENSG00000187608 ENSG00000086589 ENSG00000178999 ENSG00000100883 ENSG00000120885 ENSG00000160131 ENSG00000148719 ENSG00000242265 ENSG00000018236 ENSG00000102910 ENSG00000144231 ENSG00000177303 ENSG00000185246 ENSG00000165934 ENSG00000124541 ENSG00000142192 ENSG00000089351 ENSG00000131747 ENSG00000099194 ENSG00000198363 ENSG00000134824 ENSG00000112984 ENSG00000082805 ENSG00000100353 ENSG00000168288 ENSG00000100325 ENSG00000197746 ENSG00000087586 ENSG00000132182 ENSG00000284868 ENSG00000148396 ENSG00000147123 ENSG00000180957 ENSG00000071889 ENSG00000170266 ENSG00000123374 ENSG00000163681 ENSG00000108106 ENSG00000101210 ENSG00000005339 ENSG00000114346 ENSG00000173039 ENSG00000129911 ENSG00000163435 ENSG00000292222 ENSG00000134057 ENSG00000135446 ENSG00000177606 ENSG00000106263 ENSG00000102007 ENSG00000106153 ENSG00000187244 ENSG00000152291 PMC8293491__F6 Circulating miR-146a as a possible candidate biomarker in the indeterminate phase of Chagas disease ENSG00000140992 ENSG00000160789 ENSG00000168329 ENSG00000107562 ENSG00000102908 ENSG00000050748 ENSG00000072274 ENSG00000158195 ENSG00000095015 ENSG00000091409 ENSG00000173391 ENSG00000171791 ENSG00000118971 ENSG00000141968 ENSG00000089159 ENSG00000102189 ENSG00000159216 ENSG00000103490 ENSG00000168214 ENSG00000145623 ENSG00000156299 ENSG00000149269 ENSG00000138755 ENSG00000166501 ENSG00000154096 ENSG00000114450 ENSG00000172380 ENSG00000116701 ENSG00000043462 ENSG00000168610 ENSG00000291420 ENSG00000131828 ENSG00000187840 ENSG00000160691 ENSG00000169245 ENSG00000186810 ENSG00000138378 ENSG00000115415 ENSG00000134324 ENSG00000073861 ENSG00000131196 ENSG00000186469 PMC9465167__F1 Human immunodeficiency virus-1 core: The Trojan horse in virus–host interaction ENSG00000111605 ENSG00000183735 ENSG00000164430 PMC4730296__F1 Outline of melatonin biosynthesis and function ENSG00000065833 PMC8745614__F4A Reduced RBPMS Levels Promote Cell Proliferation and Decrease Cisplatin Sensitivity in Ovarian Cancer Cells ENSG00000104856 ENSG00000125266 ENSG00000006062 PMC6095005__F3 Mechanisms involved in the induction of depressive symptoms in inflammatory conditions (gray arrows) and potential therapeutic implications following pharmacological or nutritional interventions (blue arrows) ENSG00000171759 PMC6095005__F2 Inflammation-associated BH4 pathway ENSG00000228716 ENSG00000171759 PMC4437198__F1 Genetic Variants in the Fibroblast Growth Factor Pathway as Potential Markers of Ovarian Cancer Risk, Therapeutic Response, and Clinical Outcome ENSG00000066468 ENSG00000140285 ENSG00000077782 PMC8204019__F1 Radiation Resistance: A Matter of Transcription Factors ENSG00000115415 ENSG00000168610 PMC8293691__F2 Novel Insights and Current Evidence for Mechanisms of Atherosclerosis: Mitochondrial Dynamics as a Potential Therapeutic Target ENSG00000162711 ENSG00000239732 ENSG00000164430 ENSG00000198793 ENSG00000142082 ENSG00000171109 ENSG00000214253 PMC8226175__F1 Targeting the MYC Ubiquitination-Proteasome Degradation Pathway for Cancer Therapy ENSG00000079387 ENSG00000124422 ENSG00000063978 ENSG00000104517 ENSG00000119401 ENSG00000055483 ENSG00000121067 ENSG00000105656 ENSG00000131263 ENSG00000086758 ENSG00000127585 ENSG00000135913 ENSG00000136997 ENSG00000048028 PMC7563533__F2 Key databases as primary resources for drug repositioning ENSG00000152266 PMC3606591__F1 Novel approaches to inhibitor design for the p110B PI 3-kinase ENSG00000163914 ENSG00000135605 PMC3676754__F2A The Brassinosteroid Signaling Pathway—New Key Players and Interconnections with Other Signaling Networks Crucial for Plant Development and Stress Tolerance ENSG00000110934 PMC1065305__F1 Components of the AhR-mediated lacZ reporter assay ENSG00000069482 ENSG00000106546 PMC10818625__F2 Pharmacological interventions against necroptosis in pneumonia ENSG00000137275 ENSG00000136869 ENSG00000168404 ENSG00000285379 ENSG00000026103 PMC10818625__F1 Mechanism by which pathogenic infection causes cell necroptosis ENSG00000124256 ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000125347 ENSG00000115415 ENSG00000157625 ENSG00000136869 ENSG00000168404 ENSG00000285379 ENSG00000026103 ENSG00000164342 PMC6166407__F1 Pro-tumorigenic functions of GPNMB ENSG00000122882 ENSG00000291971 ENSG00000136235 ENSG00000137845 ENSG00000146648 PMC11898298__F6 Ironomycin cytotoxic effects alone and in combination with other drugs ENSG00000167468 ENSG00000186716 ENSG00000010671 ENSG00000198286 PMC6726297__F1 Cholesterol-dependent inflammatory response and cell death in the hepatocyte ENSG00000138075 ENSG00000042832 ENSG00000125538 ENSG00000143921 ENSG00000026103 PMC8705762__F3 Sperm-Guiding Unconventional Prostaglandins in C. elegans: Synthesis and Signaling ENSG00000118515 PMC4711336__F1 TGFB signaling and regulation ENSG00000095739 PMC4160341__F3 Rho GTPases as regulators of mitosis and cytokinesis in mammalian cells ENSG00000102606 ENSG00000114346 ENSG00000149269 PMC4142219__F3 Characterization of glycoproteins in pancreatic cyst fluid using a high performance multiple lectin affinity chromatography platform ENSG00000175535 ENSG00000240038 ENSG00000141086 ENSG00000001626 PMC7346227__F2 Primary cilia control Hedgehog pathway output ENSG00000143147 ENSG00000106571 ENSG00000136997 ENSG00000164690 ENSG00000128602 PMC5429551__F2 The dual role of TGFB in tumor progression and its association with RAC1b and RAC1 expression PMC9047778__F2 Providing a Helping Hand: Metabolic Regulation of T Follicular Helper Cells and Their Association With Disease ENSG00000198793 PMC8222406__F10 CSC-associated AKT/TSPYL5/PTEN loop signaling pathway ENSG00000184254 ENSG00000180543 ENSG00000026508 ENSG00000146648 PMC3360606__F1 Integrative Gene Regulatory Network Analysis Reveals Light-Induced Regional Gene Expression Phase Shift Programs in the Mouse Suprachiasmatic Nucleus ENSG00000146469 ENSG00000177606 ENSG00000102239 ENSG00000135577 PMC8358691__F1 Physiological impact of in vivo stable isotope tracing on cancer metabolism ENSG00000173599 ENSG00000145321 ENSG00000115419 PMC8286839__F14 Recruitment of repressors leads to termination of transcriptional responses ENSG00000087095 ENSG00000132693 PMC2720262__F1 Summary of consequences on signal transduction and brain architecture of conditional Pten or Pdk1 deletion, alone or in combination ENSG00000198793 ENSG00000102104 ENSG00000105723 PMC11274695__F4 Protein interactions in plant hormone pathways confirmed using BiFC ENSG00000143761 ENSG00000119383 ENSG00000024422 PMC11274695__F3 Interacting proteins in the classical cell signaling pathway validated using BiFC ENSG00000129474 ENSG00000142227 ENSG00000172663 ENSG00000134982 ENSG00000168036 ENSG00000109854 ENSG00000123685 ENSG00000116161 ENSG00000125249 ENSG00000136997 ENSG00000144848 ENSG00000102007 ENSG00000172936 ENSG00000175104 PMC6078990__F1 YAP regulates innate antiviral immunity via a transcription-independent mechanism ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000197905 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC6025041__F4 Metabolic pathways influenced by transcriptional factor O-GlcNAcylation ENSG00000147162 ENSG00000198408 ENSG00000185591 ENSG00000026103 PMC11825788__F2 Neuropeptides released from nerve endings and receptors on GCs are illustrated ENSG00000170608 ENSG00000291363 ENSG00000064989 ENSG00000146469 ENSG00000070985 ENSG00000124664 ENSG00000146648 ENSG00000196689 PMC6690701__F8 Several H2S-sensitive metabolite changes map to redox active nodes in central carbon metabolism ENSG00000172005 PMC4870087__F7 Dominant-negative GA subunits are a mechanism of dysregulated heterotrimeric G protein signaling in human disease ENSG00000006377 ENSG00000101333 PMC6025041__F3 HBP modulates cancer metabolism through the O-GlcNAcylation ENSG00000169710 PMC8175487__F8 Nobiletin enhances the development and quality of bovine embryos in vitro during two key periods of embryonic genome activation ENSG00000123374 PMC8323274__F6 NR1D1 suppressed the growth of ovarian cancer by abrogating the JAK/STAT3 signaling pathway ENSG00000168610 PMC6025041__F1 Hexosamine biosynthesis pathway ENSG00000147162 ENSG00000198408 ENSG00000124357 ENSG00000013375 PMC4693901__F2 Protein kinase C (PKC) involvement in cytoplasmic signal transduction pathways in the immune system ENSG00000183735 ENSG00000111537 ENSG00000134982 ENSG00000186716 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000124181 ENSG00000175104 ENSG00000276561 PMC6248440__F2 Schematic representation of miRNA (left) and piRNA (right) biogenesis ENSG00000128191 ENSG00000113360 ENSG00000132341 PMC3180046__F2 NFKB signaling pathways ENSG00000104856 ENSG00000186716 ENSG00000173039 ENSG00000111321 ENSG00000131323 ENSG00000083799 ENSG00000120913 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC8943305__F8 Clinical and Apoptotic Factors Defining and Predicting Steroid Resistance in Nephrotic Syndrome in Children ENSG00000171791 PMC10816282__F7 Proposed scheme for transcriptome stress response to APS ENSG00000144895 ENSG00000177606 PMC10745077__F6 Pro-apoptotic Bax-induced release of cytochrome stimulates the caspase signaling pathway in the mitochondria, resulting in enhanced hepatic cell apoptosis ENSG00000132906 ENSG00000164305 PMC10816282__F6 Transcription response to APS of the JNK/MAPK (A), JAK/STAT (B), Toll and Imd (C) signaling pathway genes in the control and GagrRNAi females and males ENSG00000026103 PMC11529284__F3 Sodium taurocholate co-transporting polypeptide expression ENSG00000160867 ENSG00000096717 PMC5979829__F8 LIF and the PI3K/Akt signaling pathway ENSG00000135111 ENSG00000128342 PMC5750128__F7 Schematic drawing showing the effects of IGF-1 and ALC on prepubertal Kp synthesis and release ENSG00000169047 ENSG00000198793 ENSG00000102104 ENSG00000140443 PMC8674954__F8 Committed Human CD23-Negative Light-Zone Germinal Center B Cells Delineate Transcriptional Program Supporting Plasma Cell Differentiation ENSG00000186716 ENSG00000173599 ENSG00000203710 ENSG00000145321 ENSG00000103522 ENSG00000117322 PMC4413635__F1 Cyclin alterations in diverse cancers: outcome and co-amplification network ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 ENSG00000139687 PMC8889522__F2 An insight into the mechanisms of COVID-19, SARS-CoV2 infection severity concerning Beta-cell survival and cardiovascular conditions in diabetic patients ENSG00000130234 ENSG00000184012 PMC11995161__F2 Role and regulatory mechanism of LAPTM4B in tumors ENSG00000167258 ENSG00000069869 ENSG00000112561 ENSG00000104341 ENSG00000165794 ENSG00000146648 ENSG00000057663 PMC8235525__F2 Metabolic Choreography of Maize Plants Treated with a Humic Substance-Based Biostimulant under Normal and Starved Conditions ENSG00000172005 ENSG00000154059 PMC3195649__F2 Targeted therapies for breast cancer PMC5893285__F3 Involvement of miR-126 targetome in focal adhesion signaling pathway from KEGG is shown ENSG00000169291 ENSG00000002330 ENSG00000010810 ENSG00000177606 PMC5893285__F2 miR-126 is involved in neurotrophin signaling pathway pathways including IRS1, PI3K and IKB, which their partial diagram collected from KEGG pathway is demonstrated ENSG00000182511 ENSG00000101146 ENSG00000002330 ENSG00000169047 ENSG00000175104 PMC10552782__F2 Regulatory Mechanism of Iguratimod on Signaling Pathway (IFN, interferon; TNF, Tumor necrosis factor; IL, Interleukin; Th, helper T cells; Treg, Regulatory T cells) ENSG00000111537 ENSG00000177606 PMC3948174__F1 Regulation of G protein-mediated signaling by RGS2 in the heart ENSG00000096088 ENSG00000116741 ENSG00000115271 PMC6328940__EV1 B‐RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9 R239X mice ENSG00000132423 ENSG00000167113 ENSG00000123815 ENSG00000119723 ENSG00000110871 ENSG00000088682 ENSG00000173085 ENSG00000167186 ENSG00000135469 PMC7747191__F2 Toll-like receptor signalling in B cells during systemic lupus erythematosus ENSG00000089692 ENSG00000111537 ENSG00000186716 PMC11904754__F6 GALNT proteins involved in lung cancer and pathway related ENSG00000115339 ENSG00000139629 ENSG00000257594 PMC11904754__F5 The GALNT14 protein regulates the occurrence and development of lung cancer ENSG00000058085 ENSG00000134982 ENSG00000168036 ENSG00000169851 PMC9009290__F9 Chrysin Ameliorates Influenza Virus Infection in the Upper Airways by Repressing Virus-Induced Cell Cycle Arrest and Mitochondria-Dependent Apoptosis ENSG00000135446 ENSG00000123374 PMC3849657__F1 YAP/TAZ are effectors of mechanical stress, GPCR signaling, and the Wnt signaling pathway. Mechanisms of YAP and TAZ regulation by mechanical stress, GPCR signaling, and the Wnt pathway as well as YAP/TAZ as modulators of the Wnt pathway are shown ENSG00000183734 ENSG00000109321 ENSG00000089685 ENSG00000163914 ENSG00000168036 ENSG00000198670 ENSG00000176105 ENSG00000150457 ENSG00000131023 ENSG00000089225 PMC2948275__F1 Putative functions of caspase-2 ENSG00000149311 ENSG00000175054 ENSG00000134057 PMC2100434__F2 Growth hormone-mediated JAK/STAT signal transduction ENSG00000120833 ENSG00000112964 PMC9318484__F2 Natural Products and Their Multitargeted Approach to Treat Solid Cancer ENSG00000002330 ENSG00000150907 ENSG00000169047 ENSG00000198793 PMC4196962__F6 Interleukin-1B Induces Blood–Brain Barrier Disruption by Downregulating Sonic Hedgehog in Astrocytes ENSG00000108691 ENSG00000081041 ENSG00000125538 ENSG00000164690 ENSG00000128602 ENSG00000115009 PMC7211213__F3 Therapeutic targets associated with activation of the Wnt signaling pathway ENSG00000134982 ENSG00000168036 PMC7643360__F5 Summarized diagram proposing that IGFBPs secreting PD-MSCsPRL-1 are the key antiadipogenic factors inhibiting adipogenesis in OFs from GO patients through upregulation of FAK and downregulation of the PI3K/AKT/mTOR signaling pathway ENSG00000169047 ENSG00000155792 PMC6813133__F3 ADHD gene-networks constructed with PASCAL associated genes and its FunCoup interactors ENSG00000176248 ENSG00000087586 ENSG00000136146 ENSG00000120438 ENSG00000112312 PMC6088210__F1 TLRs mediated the T cells response and programmed cell death process toward tumor environment ENSG00000183735 ENSG00000102871 ENSG00000172936 ENSG00000168040 ENSG00000150455 ENSG00000175104 PMC7760785__F2 Crosstalk between the major signaling pathway regulating autophagy and liver tumorigenesis ENSG00000177169 ENSG00000134982 ENSG00000155792 PMC2667769__F5 Defective respiration of Δisc1 in the post-diauxic phase ENSG00000122966 PMC5445208__F6 Genes involved in B-cell receptor signaling which converges to mitogen-activated protein (MAP) kinase pathway, nuclear factor KB (NFKB) pathway, and phosphoinositide 3-kinase (PI3K) pathway are the therapeutic targets of B-cell lymphomas ENSG00000124102 ENSG00000105369 ENSG00000007312 ENSG00000198793 ENSG00000010671 ENSG00000198286 PMC8350857__F2 Promoting Effect of Traumatic Brain Injury on the Incidence and Progression of Glioma: A Review of Clinical and Experimental Research ENSG00000284774 ENSG00000149212 ENSG00000141448 ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC5161407__F4 Nuclear DNA damage signalling to mitochondria in ageing ENSG00000132906 ENSG00000177169 ENSG00000123395 ENSG00000002330 ENSG00000158828 ENSG00000168040 ENSG00000164305 ENSG00000136048 ENSG00000149311 ENSG00000120868 ENSG00000096717 ENSG00000064012 ENSG00000026103 PMC7211213__F1 Simplified overview of canonical Wnt signaling pathway activation ENSG00000134982 ENSG00000168036 PMC6586148__F6 SHP2–ERK1/2 inhibition and STAT3 activation by Sunitinib ENSG00000122180 ENSG00000135424 PMC6190667__F8 Carbon contribution of medium ingredients to riboflavin based on combined parallel 13C-labeled tracer studies using [13C2] glycine, [13C] formate, [13C5] glutamate, and [U13C] yeast extract ENSG00000159224 ENSG00000172005 ENSG00000078098 PMC8833570__F1 KRAS and RAS-MAPK Pathway Deregulation in Mature B Cell Lymphoproliferative Disorders ENSG00000177455 ENSG00000095585 ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000198793 ENSG00000197943 ENSG00000010671 ENSG00000196712 PMC3328893__F1 Physiological and pathophysiological stimuli regulate tonicity-responsive enhanced binding protein (TonEBP) in diverse cell types PMC7484670__F6 MTOR-miR-143 signaling axis in the pathogenesis of AD ENSG00000163207 ENSG00000131724 ENSG00000143631 PMC4026357__F1 Importance of Breast Cancer Subtype in the Development of Androgen Receptor Directed Therapy ENSG00000065361 ENSG00000168036 PMC8850641__F9 Identification of Potential Blind-Side Hypermelanosis-Related lncRNA–miRNA–mRNA Regulatory Network in a Flatfish Species, Chinese Tongue Sole (Cynoglossus semilaevis) ENSG00000080166 ENSG00000107165 PMC8137895__F1 Implications the Role of miR-155 in the Pathogenesis of Autoimmune Diseases ENSG00000128191 ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC6457262__F1 Galantamine-memantine combination superior to donepezil-memantine combination in Alzheimer’s disease: critical dissection with an emphasis on kynurenic acid and mismatch negativity PMC6611005__F9 Anti-pancreatic cancer pathway of Wumei Pill ENSG00000132906 ENSG00000104365 ENSG00000002330 ENSG00000100906 ENSG00000109320 ENSG00000102871 ENSG00000138798 ENSG00000269335 ENSG00000173039 ENSG00000213341 ENSG00000171791 ENSG00000168040 ENSG00000127191 ENSG00000073756 ENSG00000164305 ENSG00000128052 ENSG00000177606 ENSG00000136997 ENSG00000123374 ENSG00000172936 ENSG00000175104 ENSG00000146648 PMC5233600__F1 NLRP3 and AIM2 in inflammasome activation during Brucella abortus infection ENSG00000162711 ENSG00000163568 ENSG00000172936 PMC8966686__F10 Integrative Transcriptomics and Proteomics Analysis Provide a Deep Insight Into Bovine Viral Diarrhea Virus-Host Interactions During BVDV Infection ENSG00000162711 ENSG00000172893 ENSG00000138794 ENSG00000198793 ENSG00000169710 ENSG00000168040 ENSG00000099194 ENSG00000135341 ENSG00000164305 ENSG00000276561 ENSG00000111537 ENSG00000151778 ENSG00000088888 ENSG00000184995 ENSG00000116133 ENSG00000177606 ENSG00000147896 ENSG00000131323 ENSG00000175104 PMC3744088__F6 Extent to which glutamate (GLU) is oxidized in astrocytes seems to increase particularly during higher glutamate concentrations ENSG00000122966 ENSG00000173599 ENSG00000172005 PMC12188105__F1 Glutamine signaling pathway and metabolism in cancer ENSG00000125166 ENSG00000151012 ENSG00000136997 ENSG00000112561 ENSG00000166123 ENSG00000115419 PMC6886699__F9 Adenoviral Transduction of EGFR into Pregnancy-Adapted Uterine Artery Endothelial Cells Remaps Growth Factor Induction of Endothelial Dysfunction ENSG00000291971 ENSG00000138798 ENSG00000112715 ENSG00000138741 ENSG00000146648 PMC7374824__F1 TLR signaling ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000276561 ENSG00000164342 PMC2311275__F4 Following biological functions (central carbon pathway, redox and respiration coordination, phosphate starvation, nitrogen gestion, carbohydrates, nucleotide and amino acids metabolism, ribosome activity) ENSG00000122966 ENSG00000122218 ENSG00000173599 ENSG00000172005 ENSG00000105697 PMC12188105__F4 Targeting glutamine metabolic reprogramming in cancers ENSG00000125166 ENSG00000151012 ENSG00000198793 ENSG00000136997 ENSG00000111371 ENSG00000103257 ENSG00000089163 ENSG00000166123 ENSG00000146648 PMC12188105__F2 LncRNAs regulate glutamine metabolism in cancer ENSG00000128272 ENSG00000253352 ENSG00000115419 PMC6504851__F2 Diagram showing differentially expressed genes in BXW-resistant and BXW-susceptible genotypes of banana after inoculation with Xanthomonas campestris pv ENSG00000105722 ENSG00000178860 PMC3261702__F4 Structural coverage of the core vision pathway and its links to other functional modules ENSG00000167553 ENSG00000123416 ENSG00000077522 ENSG00000165527 ENSG00000169032 ENSG00000163914 ENSG00000168374 ENSG00000166501 ENSG00000130402 ENSG00000288263 ENSG00000184304 ENSG00000281857 ENSG00000168530 ENSG00000109061 ENSG00000186326 ENSG00000109047 ENSG00000197694 ENSG00000198515 ENSG00000156219 ENSG00000120805 ENSG00000006451 ENSG00000144118 ENSG00000145321 ENSG00000072110 ENSG00000127824 PMC5821407__F4 Proteomic analysis of the human retina reveals region-specific susceptibilities to metabolic- and oxidative stress-related diseases ENSG00000178127 ENSG00000211445 ENSG00000267855 ENSG00000100412 ENSG00000117118 ENSG00000178741 ENSG00000126267 ENSG00000110717 ENSG00000099795 ENSG00000010256 ENSG00000159399 ENSG00000062485 PMC37430__F1 Simplified steps of Okazaki fragment maturation during DNA lagging strand synthesis (for further details see refs ENSG00000138346 PMC8894711__F2 Novel Molecular Therapeutics Targeting Signaling Pathway to Control Hepatitis B Viral Infection ENSG00000164430 ENSG00000168036 PMC8894711__F1 Novel Molecular Therapeutics Targeting Signaling Pathway to Control Hepatitis B Viral Infection ENSG00000172936 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000064012 ENSG00000184216 PMC12123228__F2 Proposed mechanisms of BTKi-induced hypertension ENSG00000148400 ENSG00000010671 PMC3973006__F8 Schematic model of TGFB signaling pathways for CRP2 induction in VSMCs ENSG00000175183 PMC12123228__F1 BCR signaling pathway and mechanism of action of BTKi ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000198793 ENSG00000197943 ENSG00000010671 PMC5952256__F1 The mechanism of extracellular vesicles (EVs) release differs among different types of EV ENSG00000106683 ENSG00000165527 PMC3469596__F8 Neutral lipid and phospholipid biosynthetic pathways ENSG00000166819 ENSG00000130164 ENSG00000042832 ENSG00000173599 ENSG00000198670 PMC8375160__F10 Mutual regulation between chicken telomerase reverse transcriptase and the Wnt/Beta-catenin signalling pathway inhibits apoptosis and promotes the replication of ALV-J in LMH cells ENSG00000168036 ENSG00000196628 PMC7167271__F11 Effect of RPMP and emodin on genes expression profiles ENSG00000042832 ENSG00000161533 PMC5584530__F8 Cell surface HSPGs consists of a protein core linking several linear heparan sulfate (HS) chains ENSG00000281324 ENSG00000134982 ENSG00000168036 ENSG00000132964 PMC2921605__F1 PIK3/Akt/mTOR Pathway ENSG00000198793 PMC3022184__F2 A proposed mechanism of TGFA/EGFR/ras-MAPK activation loop in HNSCC ENSG00000110395 ENSG00000163235 ENSG00000146648 PMC7307792__F4 Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei ENSG00000100033 PMC7564912__F8 Diagram indicating the mechanism of IITZ-01-induced TRAIL sensitization ENSG00000110395 ENSG00000168040 PMC6082928__F3 LMP1 in the carcinogenesis of nasopharyngeal carcinomas ENSG00000149311 ENSG00000105639 ENSG00000168610 ENSG00000146648 PMC11829765__F8 Lineage diversification in the ureteric mesenchyme ENSG00000128918 ENSG00000188064 ENSG00000141052 ENSG00000164690 PMC8889569__F4 Phosphatidylcholine-Derived Lipid Mediators: The Crosstalk Between Cancer Cells and Immune Cells ENSG00000198793 ENSG00000198670 ENSG00000064547 ENSG00000171517 ENSG00000147145 PMC6082928__F6 Signaling pathways engaged by the LMP2A gene ENSG00000186716 ENSG00000168036 PMC4766172__F1 Lysine degradation pathways in mammals ENSG00000179761 ENSG00000105607 ENSG00000181192 ENSG00000127884 PMC6191511__F1 Functional analysis of genes differentially expressed in response to L-lactate after 1 h ENSG00000109320 ENSG00000111837 ENSG00000166484 PMC6530608__F1 Mitochondria and ER in activation of the NLRP3 inflammasome ENSG00000162711 ENSG00000134326 ENSG00000163568 PMC3617401__F2 Emerging actions of the nuclear receptor LRH-1 in the gut ENSG00000168036 ENSG00000196628 PMC9195630__F10 Long Non-Coding RNA TMPO-AS1 Promotes GLUT1-Mediated Glycolysis and Paclitaxel Resistance in Endometrial Cancer Cells by Interacting With miR-140 and miR-143 ENSG00000157227 ENSG00000159399 PMC5839790__F1 Classic autophagy compared with related trafficking pathways ENSG00000177169 ENSG00000198382 ENSG00000265808 ENSG00000083290 ENSG00000126775 ENSG00000144848 ENSG00000189403 ENSG00000099940 ENSG00000118640 ENSG00000057663 ENSG00000136874 PMC2992267__F8 A schematic model showing the proposed biosynthetic pathway for cutin ENSG00000158669 ENSG00000198670 PMC6912224__F2 SMAD- and Non-SMAD-dependent TGFB signaling ENSG00000198793 ENSG00000163914 PMC11855511__F8 Construction of DEmiRNA-mRNA expression regulatory network based on JAK-STAT signaling pathway and phagosome ENSG00000047597 PMC7864954__F6 miR156-based regulation of SPL13 enhances photosynthesis, phenylpropanoid, and ABA biosynthesis in response to flooding ENSG00000115263 ENSG00000173599 PMC7919044__F2 G protein-coupled receptor (GPCR) kinase 5 (GRK5) activities within cardiomyocytes, cancer, and neuronal cells ENSG00000094631 ENSG00000291971 ENSG00000113070 ENSG00000138798 ENSG00000171791 ENSG00000146648 PMC5811627__F1 Outline of main altered pathways in pancreatic neuroendocrine tumours ENSG00000100150 ENSG00000133895 ENSG00000083093 ENSG00000182944 ENSG00000198793 ENSG00000181555 ENSG00000139618 ENSG00000183765 ENSG00000151702 ENSG00000012048 ENSG00000134086 ENSG00000132781 ENSG00000051180 ENSG00000055609 ENSG00000127616 ENSG00000189079 ENSG00000125650 PMC4415242__F8 The three axes of the UPR in Drosophila brains activated by HTorAΔE ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC4234565__F3 Circadian pathways ENSG00000177455 ENSG00000065361 ENSG00000198793 ENSG00000128052 ENSG00000112715 ENSG00000178568 ENSG00000110042 ENSG00000140443 ENSG00000168685 PMC8072385__F2 Metabolic Syndrome and Autophagy: Focus on HMGB1 Protein ENSG00000198793 ENSG00000272398 ENSG00000189403 ENSG00000162924 ENSG00000057663 PMC9320351__F3 Vitamin D Derivatives in Acute Myeloid Leukemia: The Matter of Selecting the Right Targets ENSG00000019186 PMC5362547__F2A Hippo signaling pathway provides novel anti-cancer drug targets ENSG00000126016 ENSG00000186575 ENSG00000163914 ENSG00000114978 ENSG00000150457 ENSG00000131023 PMC8909913__F1 Cancer-Associated Fibroblasts: Mechanisms of Tumor Progression and Novel Therapeutic Targets ENSG00000170365 ENSG00000126016 ENSG00000134982 ENSG00000168036 ENSG00000081051 ENSG00000132849 PMC7456423__F6 Squalene synthase promotes the invasion of lung cancer cells via the osteopontin/ERK pathway ENSG00000157933 ENSG00000291971 PMC3720596__F1 NRAS mutant melanoma – undrugable? ENSG00000198793 PMC6346552__F9 Proposed molecular model of non-coding RNAs involved in CXCL12/CXCR4-induced CRC invasion and progression ENSG00000107562 ENSG00000163914 ENSG00000121966 PMC9204587__F1 Cholesterol and Its Derivatives: Multifaceted Players in Breast Cancer Progression ENSG00000160752 ENSG00000113161 PMC8533474__F5 Combined Metabolic Activators Decrease Liver Steatosis by Activating Mitochondrial Metabolism in Hamsters Fed with a High-Fat Diet ENSG00000183549 ENSG00000275543 ENSG00000065911 ENSG00000132840 ENSG00000100033 ENSG00000101473 ENSG00000131844 ENSG00000120254 ENSG00000111058 ENSG00000115850 ENSG00000100714 ENSG00000092621 ENSG00000167468 ENSG00000111181 ENSG00000005187 ENSG00000083807 ENSG00000166123 ENSG00000105552 ENSG00000116761 ENSG00000126432 ENSG00000026103 ENSG00000167701 PMC7577395__F2 Representative contributions of ion channels to glioma cell proliferation ENSG00000092439 ENSG00000198793 PMC6592760__F2 Metabolic regulation of cell growth and proliferation ENSG00000128272 ENSG00000092621 ENSG00000135069 ENSG00000070669 PMC9009531__F1 Lipid Metabolic Process Involved in Oocyte Maturation During Folliculogenesis ENSG00000157184 ENSG00000005187 ENSG00000123983 PMC8063501__F2 DSB repair pathway choice ENSG00000143799 ENSG00000012048 ENSG00000105486 ENSG00000080345 ENSG00000253251 ENSG00000171984 ENSG00000122376 ENSG00000051180 ENSG00000177084 ENSG00000310560 ENSG00000139618 PMC11357158__F2 TGFB1/Smad pathway mediated by identified ncRNAs ENSG00000163430 ENSG00000143768 ENSG00000108423 ENSG00000108821 PMC11357158__F1 Biological pathways and interactions of three ncRNAs ENSG00000128191 ENSG00000113360 PMC3267157__F2 P73 pathway and its regulators.A simplified view of the p73 pathway, of its regulators, and of the molecules that directly or indirectly can modulate its function ENSG00000149311 ENSG00000127445 ENSG00000078747 ENSG00000198793 ENSG00000274089 PMC11357158__F3 Hippo and Hedgehog pathways mediated by identified ncRNAs ENSG00000166813 ENSG00000197905 ENSG00000114978 ENSG00000007866 ENSG00000128602 ENSG00000131023 ENSG00000074219 ENSG00000109670 PMC4232283__F8 Proposed working model ENSG00000138185 PMC11357158__F5 Wnt/Beta-catenin pathway and associated ncRNAs ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC9100112__F9 Gp130-Mediated STAT3 Activation Contributes to the Aggressiveness of Pancreatic Cancer through H19 Long Non-Coding RNA Expression ENSG00000128342 ENSG00000168610 PMC3498840__F1 TLR signaling overview: the TLR family can be subdivided into two categories ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000276561 ENSG00000164342 PMC12013188__F14 Signaling pathways regulating the HAG ENSG00000162711 ENSG00000113070 ENSG00000172936 ENSG00000136869 ENSG00000166670 ENSG00000175104 ENSG00000106100 ENSG00000168610 ENSG00000146648 ENSG00000079999 PMC4993044__F3 Proposed sequence of events following aberrant fatty acid reabsorption at the apical surface of the proximal tubule in the setting of nephrotic syndrome ENSG00000151726 ENSG00000042832 ENSG00000163631 PMC2522278__F2 Comparative Analysis of mRNA Targets for Human PUF-Family Proteins Suggests Extensive Interaction with the miRNA Regulatory System ENSG00000181788 ENSG00000070831 ENSG00000134982 ENSG00000143878 ENSG00000138798 ENSG00000168036 ENSG00000090776 ENSG00000196628 ENSG00000160691 ENSG00000112685 ENSG00000115415 ENSG00000139725 ENSG00000177606 ENSG00000077782 ENSG00000146648 ENSG00000105723 PMC2682371__F2 ErbB proteins are type I transmembrane receptor tyrosine kinases ENSG00000065361 ENSG00000291971 ENSG00000167941 ENSG00000198793 ENSG00000136997 ENSG00000168610 ENSG00000146648 ENSG00000178568 PMC8712868__F2 Sprifermin: Effects on Cartilage Homeostasis and Therapeutic Prospects in Cartilage-Related Diseases ENSG00000168958 ENSG00000150907 ENSG00000125538 ENSG00000198793 ENSG00000156427 PMC4889588__F1 Schematic depiction of oncogenic MYC signal transduction ENSG00000198793 ENSG00000177606 ENSG00000136997 PMC4591983__F6 Identification of Target Genes Involved in Wound Healing Angiogenesis of Endothelial Cells with the Treatment of a Chinese 2-Herb Formula ENSG00000176884 ENSG00000115415 ENSG00000137203 ENSG00000189108 ENSG00000171951 ENSG00000168610 PMC4936107__F1 (Left) Model for sulfur assimilation ENSG00000182511 ENSG00000110395 PMC4591983__F5 Identification of Target Genes Involved in Wound Healing Angiogenesis of Endothelial Cells with the Treatment of a Chinese 2-Herb Formula ENSG00000113196 ENSG00000119888 ENSG00000089685 ENSG00000120211 ENSG00000172404 ENSG00000006062 PMC4432002__F2 Role of the BM niche in MM pathogenesis ENSG00000108691 ENSG00000101751 ENSG00000107562 ENSG00000163235 ENSG00000113520 ENSG00000101425 PMC4049967__F1 IL-15 and IL-17F are differentially regulated and expressed in mycosis fungoides (MF) ENSG00000105639 ENSG00000112115 ENSG00000168610 PMC6816428__F1 Crosstalk between the Hippo pathway and Multi-vulval class B (MuvB) complexes ENSG00000157540 ENSG00000205250 ENSG00000150457 PMC8817131__F3 PGC‐1A protects from myocardial ischaemia‐reperfusion injury by regulating mitonuclear communication ENSG00000181019 ENSG00000106459 PMC3991464__F1 Four pathways of androgen metabolism ENSG00000151632 PMC5789791__F1 Quantitative Proteomic Profiling Reveals Hepatic Lipogenesis and Liver X Receptor Activation in the PANDER Transgenic Model ENSG00000042832 ENSG00000260428 PMC8105286__F1 Biophysics of Notch Signaling ENSG00000168214 ENSG00000138798 ENSG00000166278 ENSG00000137845 PMC6436556__F3 A model showing how the cargo in exosomes can potentially change ENSG00000146648 ENSG00000011347 ENSG00000111737 PMC9255252__F1 Characteristics of leukemic stem cells in acute leukemia and potential targeted therapies for their specific eradication ENSG00000134982 PMC8036803__F2 Msi1 impact on cell cycle and division ENSG00000118007 ENSG00000134982 ENSG00000167513 ENSG00000077514 ENSG00000205250 ENSG00000073111 ENSG00000091651 ENSG00000198056 ENSG00000276876 ENSG00000093009 ENSG00000012048 ENSG00000101868 ENSG00000138778 ENSG00000101945 ENSG00000144554 ENSG00000101773 ENSG00000078900 ENSG00000089685 ENSG00000014138 ENSG00000077782 ENSG00000137267 ENSG00000282899 ENSG00000135097 ENSG00000138346 ENSG00000092853 ENSG00000164109 ENSG00000131747 ENSG00000101224 ENSG00000161888 ENSG00000118655 ENSG00000117399 ENSG00000139618 ENSG00000094804 ENSG00000146670 ENSG00000111602 ENSG00000156970 ENSG00000109805 ENSG00000132646 ENSG00000198554 ENSG00000149503 ENSG00000137804 ENSG00000123416 ENSG00000188229 ENSG00000087586 ENSG00000135476 ENSG00000277273 ENSG00000145386 ENSG00000092470 ENSG00000132383 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000122565 ENSG00000253729 ENSG00000171320 ENSG00000108055 ENSG00000145604 ENSG00000198901 ENSG00000101972 ENSG00000151503 ENSG00000176208 ENSG00000171848 ENSG00000197299 ENSG00000149554 ENSG00000133119 ENSG00000080839 ENSG00000175305 PMC7923925__F1 The Hippo Pathway in Breast Cancer Carcinogenesis, Prognosis, and Treatment: A Systematic Review ENSG00000129474 ENSG00000167601 ENSG00000186575 ENSG00000136997 ENSG00000197905 ENSG00000007866 ENSG00000074219 PMC8807040__F8 Liensinine Inhibits Osteosarcoma Growth by ROS-Mediated Suppression of the JAK2/STAT3 Signaling Pathway ENSG00000135446 ENSG00000105810 ENSG00000168610 PMC5620328__F1 Long non-coding RNAs associated with non-small cell lung cancer ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8378993__F1 Computer-aided prediction of inhibitors against STAT3 for managing COVID-19 associated cytokine storm ENSG00000099985 ENSG00000242689 ENSG00000128342 ENSG00000168610 PMC9558278__F2 Identification of key gene networks controlling polysaccharide accumulation in different tissues of Polygonatum cyrtonema Hua by integrating metabolic phenotypes and gene expression profiles ENSG00000109814 ENSG00000112699 PMC5346727__F3 Investigating the mechanism of hepatocellular carcinoma progression by constructing genetic and epigenetic networks using NGS data identification and big database mining method ENSG00000162889 ENSG00000130522 ENSG00000269335 ENSG00000148926 ENSG00000168067 ENSG00000197442 ENSG00000105647 ENSG00000169032 ENSG00000101224 ENSG00000221823 ENSG00000148660 ENSG00000126247 ENSG00000177606 ENSG00000048052 ENSG00000083799 ENSG00000145349 ENSG00000146648 PMC1905373__F7 Mechanism of complement-dependent haemolysis via the lectin pathway: role of the complement regulatory proteins ENSG00000166278 ENSG00000182326 PMC10816532__F3 Potential mechanisms underlying the inhibitory effects of magnesium on vascular calcification ENSG00000092439 ENSG00000168036 ENSG00000036828 PMC7432830__F4 HSP90 involvement in TGFB signaling cascade PMC5346727__F5 Investigating the mechanism of hepatocellular carcinoma progression by constructing genetic and epigenetic networks using NGS data identification and big database mining method ENSG00000152782 ENSG00000137834 ENSG00000285109 ENSG00000109320 ENSG00000269335 ENSG00000099860 ENSG00000205250 ENSG00000101224 ENSG00000127191 ENSG00000168610 ENSG00000142166 ENSG00000169967 ENSG00000077150 ENSG00000117650 ENSG00000126247 ENSG00000177606 ENSG00000136997 ENSG00000125538 ENSG00000083799 ENSG00000292332 ENSG00000168685 PMC5346727__F4 Investigating the mechanism of hepatocellular carcinoma progression by constructing genetic and epigenetic networks using NGS data identification and big database mining method ENSG00000152782 ENSG00000162889 ENSG00000137834 ENSG00000285109 ENSG00000109320 ENSG00000130522 ENSG00000269335 ENSG00000148926 ENSG00000168067 ENSG00000205250 ENSG00000101224 ENSG00000127191 ENSG00000117650 ENSG00000126247 ENSG00000177606 ENSG00000136997 ENSG00000048052 ENSG00000083799 PMC9355870__F7 SLC35B2 is a vulnerability in YAP1-driven MAPKi-resistant, BRAF mutant melanoma ENSG00000167601 ENSG00000065361 ENSG00000113070 ENSG00000157593 ENSG00000146648 PMC11748510__F10 Scheme summarizing the inhibitory effect of baicalein on PRRSV infection ENSG00000291971 ENSG00000178732 ENSG00000146648 PMC7902093__F3 Environmental mechanisms of orofacial clefts ENSG00000070193 ENSG00000141448 ENSG00000168036 ENSG00000164690 ENSG00000164305 PMC2731267__F1 Some putative molecular mechanisms that underlie the antineoplastic activity of mesalazine ENSG00000134982 ENSG00000146648 PMC7902093__F2 Environmental mechanisms of orofacial clefts ENSG00000110711 ENSG00000163235 ENSG00000291971 ENSG00000106546 PMC2912554__F6 Tumor suppressor pathways control Mdm2 function ENSG00000135446 ENSG00000105810 PMC7902093__F1 Environmental mechanisms of orofacial clefts ENSG00000162624 ENSG00000148400 ENSG00000120149 ENSG00000163132 ENSG00000106546 PMC5501134__F5 Complex and context dependent functions of the Slit/Robo signaling in angiogenesis ENSG00000145147 ENSG00000154133 ENSG00000291971 ENSG00000163914 ENSG00000165527 PMC6002803__F1 Reciprocal Signaling Between Translational Control Pathways and Synaptic Proteins in Autism Spectrum Disorders PMC9421970__F2 microRNA expression in acute myeloid leukaemia: New targets for therapy? ENSG00000120833 ENSG00000165891 ENSG00000130758 ENSG00000078399 ENSG00000198793 ENSG00000100697 ENSG00000169032 ENSG00000118971 ENSG00000166068 ENSG00000144677 ENSG00000102145 ENSG00000004660 ENSG00000117525 ENSG00000150907 ENSG00000189403 ENSG00000105810 ENSG00000096717 ENSG00000026103 ENSG00000143995 ENSG00000109670 PMC6320978__F1 Schematic overview of the Nucleotide Excision Repair (NER) pathway ENSG00000012061 ENSG00000132646 ENSG00000136936 PMC6405523__F4 IIP-effectors in FOXJ1 regulatory network and their probable ciliary associations ENSG00000110330 ENSG00000135547 ENSG00000175866 ENSG00000134982 ENSG00000112530 ENSG00000110274 ENSG00000114446 ENSG00000140463 ENSG00000148498 ENSG00000134086 ENSG00000183735 ENSG00000129654 ENSG00000164066 ENSG00000163914 ENSG00000113558 ENSG00000136997 ENSG00000148175 ENSG00000113971 ENSG00000128513 ENSG00000173406 ENSG00000277707 ENSG00000023445 ENSG00000166167 ENSG00000142192 ENSG00000147162 ENSG00000167632 ENSG00000130638 ENSG00000170264 ENSG00000117399 ENSG00000136603 ENSG00000102981 ENSG00000147601 ENSG00000285379 ENSG00000264364 ENSG00000197579 ENSG00000070831 ENSG00000119401 ENSG00000077522 ENSG00000165280 ENSG00000168036 ENSG00000166848 ENSG00000169967 ENSG00000150991 ENSG00000100629 ENSG00000197386 ENSG00000185591 ENSG00000132535 ENSG00000078668 ENSG00000269335 ENSG00000173039 ENSG00000106511 ENSG00000168040 ENSG00000092330 ENSG00000102977 ENSG00000145604 ENSG00000143156 ENSG00000188878 ENSG00000067606 ENSG00000167131 ENSG00000125124 PMC6317572__F2 Common downstream targets for cancers of the breast (blue dots), colon (green dots), lung (red dots), and prostate (brown dots) ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000124762 PMC4089452__F2 Genetic mechanisms and signaling pathways in autosomal dominant polycystic kidney disease ENSG00000291971 ENSG00000136997 ENSG00000168036 ENSG00000096717 PMC4003878__F2 GSK3B and the control of infectious bacterial diseases ENSG00000168036 ENSG00000105639 PMC7911491__F3 Effects of squalene in the NF-ƙB pathway ENSG00000170458 ENSG00000125538 ENSG00000172936 PMC9575701__F3 An emerging role for cellular crosstalk in the cancer stem cell niche ENSG00000137033 PMC3836174__F5 Hallmarks of Aging ENSG00000198793 ENSG00000096717 PMC9575701__F1 An emerging role for cellular crosstalk in the cancer stem cell niche ENSG00000041982 ENSG00000128342 ENSG00000112715 ENSG00000049768 ENSG00000073756 ENSG00000115594 ENSG00000135605 PMC8813987__F9 Pathway that signal prolonged cutaneous allodynia elicited by CGRP released and associated with neurogenic inflammation ENSG00000132329 ENSG00000104321 ENSG00000196689 PMC7288655__F9 TGFB signaling pathway ENSG00000111537 ENSG00000095739 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000164093 ENSG00000111816 PMC9549367__F1 Irisin in physiology and pathology ENSG00000100234 ENSG00000162711 ENSG00000137845 ENSG00000204217 PMC3541267__F3 Signaling pathways driving mesenchymal stem cells to differentiate into lineages found in reparative disorders ENSG00000169884 ENSG00000168036 ENSG00000111186 PMC6774117__F10 NGF-driven differentiation of PC12 cells requires a signal(s) generated from the UPAR immediate-early gene product ENSG00000173599 PMC4346319__F2 HIF Transcription Factors, Inflammation, and Immunity ENSG00000111537 ENSG00000075213 ENSG00000007171 PMC5161754__F7 EGFR activation during CRC progression through demethylation and subsequent upregulation of EREG at the adenoma–carcinoma transition ENSG00000134982 ENSG00000124882 ENSG00000146648 PMC10671577__F3 MAPK signaling pathway containing T ENSG00000172680 ENSG00000157764 ENSG00000138798 ENSG00000213341 ENSG00000130159 ENSG00000101224 ENSG00000127191 ENSG00000102678 ENSG00000117020 ENSG00000170458 ENSG00000134853 ENSG00000183864 ENSG00000146648 ENSG00000026103 PMC7917723__F1 Absorption, and excretion pathway of gut-derived uremic toxins ENSG00000196502 ENSG00000130649 PMC9313309__F2 Mouse Models for Application in Colorectal Cancer: Understanding the Pathogenesis and Relevance to the Human Condition ENSG00000134982 ENSG00000168036 ENSG00000170989 ENSG00000168610 PMC5991449__F3 Overview of the pathways involved in odd and even fatty acid production including the link with the TCA and methyl citrate cycles in Yarrowia lipolytica ENSG00000100412 ENSG00000026103 PMC7586293__F2 |Central metabolic pathways are driven not only by post-transcriptional changes but also by the adaptation of protein concentration upon the induction of insulin resistance ENSG00000100412 ENSG00000198793 ENSG00000141564 ENSG00000105953 ENSG00000160999 ENSG00000196396 ENSG00000251493 ENSG00000026103 PMC6476316__F4 Mutations in the bone morphogenetic protein-signaling pathway are linked to hereditary hemorrhagic telangiectasia and pulmonary artery hypertension ENSG00000139567 ENSG00000120693 ENSG00000204217 ENSG00000113360 PMC10313365__F8 Roadmap of molecular changes and cellular phenotypes when cells lose MLL3/4-COMPASS ENSG00000129691 ENSG00000162961 ENSG00000196363 PMC11012155__F1 Endocrine Disruption Chemical-Regulated Aryl Hydrocarbon Receptor Activity in the Pathogenesis of Pancreatic Diseases and Cancer ENSG00000110711 ENSG00000140465 ENSG00000106546 PMC8499523__F6 Transcriptomic analysis of the seminal vesicle response to the reproductive toxicant acrylamide ENSG00000181104 ENSG00000056972 ENSG00000122877 ENSG00000168036 ENSG00000150093 ENSG00000145386 ENSG00000166147 ENSG00000106546 ENSG00000072571 ENSG00000196557 ENSG00000011422 ENSG00000138755 ENSG00000164400 ENSG00000125810 ENSG00000135124 ENSG00000179348 ENSG00000135919 ENSG00000168028 ENSG00000100906 ENSG00000269335 ENSG00000100526 ENSG00000119147 ENSG00000204361 ENSG00000071564 ENSG00000169245 ENSG00000275214 ENSG00000111537 ENSG00000224320 ENSG00000162409 ENSG00000137077 ENSG00000108700 ENSG00000170989 ENSG00000127948 PMC4419739__F4 Cellular and signaling pathway view of gene expression changes during alcohol withdrawal ENSG00000065833 ENSG00000177606 PMC3267732__F4 Deeply Branching Thermophilic Bacterium with an Ancient Acetyl-CoA Pathway Dominates a Subsurface Ecosystem ENSG00000197713 ENSG00000127948 PMC3912487__F1 The sphingolipid rheostat in AD context ENSG00000063176 ENSG00000196591 PMC8072960__F3 Androgens and Androgen Receptor in Human Bladder Cancer ENSG00000163464 ENSG00000149968 ENSG00000277893 PMC8072960__F1 Androgens and Androgen Receptor in Human Bladder Cancer ENSG00000129214 ENSG00000277893 PMC12024137__F4 Research Progress on Hypoglycemic Effects and Molecular Mechanisms of Flavonoids: A Review ENSG00000128272 ENSG00000144895 PMC4442386__F8 Model for the overall disruption of IFN responses by SFTSV through NSs hijacking of signaling proteins in IBs ENSG00000183735 ENSG00000213928 ENSG00000115415 PMC6262249__F2 Role of macrophages in hepatitis C virus infection-associated inflammation ENSG00000174125 ENSG00000162711 ENSG00000125538 ENSG00000172936 PMC9466593__F1 Effect of antifungal resistance development on the virulence of Candida species ENSG00000140743 ENSG00000163631 PMC6831489__F5 Schematic summary of the responses on energy metabolic pathway reprogramming by genotoxic or non-genotoxic hepatocarcinogens in rat liver cells ENSG00000143158 ENSG00000285390 ENSG00000115419 PMC12024137__F3 Research Progress on Hypoglycemic Effects and Molecular Mechanisms of Flavonoids: A Review ENSG00000150907 ENSG00000169047 ENSG00000139515 PMC8846368__F2 Targeting Nutrient Dependency in Cancer Treatment ENSG00000163930 ENSG00000151012 ENSG00000136997 ENSG00000099810 ENSG00000121879 ENSG00000079999 PMC8846368__F1 Targeting Nutrient Dependency in Cancer Treatment ENSG00000151012 ENSG00000070669 ENSG00000115419 PMC4378640__F4 Schematic presentation of chloroplast proteins affected in executer mutants and WT plants after light treatment compared to WT plants under normal or growth light conditions, as shown in Table 3 ENSG00000047410 ENSG00000197713 ENSG00000173599 PMC4982039__F1 Hypoxia‐induced changes in mitochondrial metabolism ENSG00000122966 ENSG00000100412 ENSG00000173599 ENSG00000172005 PMC8894956__F4 First-line immunotherapy or angiogenesis inhibitor plus chemotherapy for HER2-altered NSCLC: a retrospective real-world POLISH study ENSG00000183735 ENSG00000164430 ENSG00000111537 PMC9508558__F8 Carboxylesterase 2 induces mitochondrial dysfunction via disrupting lipid homeostasis in oral squamous cell carcinoma ENSG00000172831 ENSG00000136997 ENSG00000026103 PMC6375688__F1 Proteostasis regulation ENSG00000128272 ENSG00000144895 PMC6487307__F1 Polyamine metabolic pathway ENSG00000168003 ENSG00000088826 ENSG00000148832 ENSG00000123505 ENSG00000182551 ENSG00000116649 ENSG00000102172 PMC8186080__F7 Spermidine induces cytoprotective autophagy of female germline stem cells in vitro and ameliorates aging caused by oxidative stress through upregulated sequestosome-1/p62 expression ENSG00000198793 ENSG00000145782 PMC5882219__F3 Reciprocal regulation of YAP by TRIO-RAC1 signaling and the Hippo pathway ENSG00000038382 ENSG00000020633 PMC3056141__F1 DNA-mediated activation of innate immune signaling ENSG00000183735 ENSG00000163568 ENSG00000131323 ENSG00000168040 PMC4885841__F6 Schematic diagram demonstrating the immunomodulatory and therapeutic effects that grafted stem cells exerted on the recipient upon transplantation ENSG00000178860 ENSG00000138798 ENSG00000136869 ENSG00000164342 PMC9209741__F3 Medulloblastoma and the DNA Damage Response ENSG00000149311 ENSG00000175054 ENSG00000002330 PMC7847335__F1 Toll-like receptor-signaling pathway during pulmonary infections ENSG00000136869 ENSG00000150455 PMC3173728__F1 In this figure we show the two main pathways to apoptosis, and their interaction through the molecule BID, since death receptors activate the intrinsic pathway by activating BID ENSG00000120868 ENSG00000171791 ENSG00000168040 ENSG00000026103 PMC2862880__F3 Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer ENSG00000151632 ENSG00000277893 ENSG00000203857 ENSG00000187134 PMC7199629__F2 Regulatory mechanisms and biological functions of MTHFD2 in cancer ENSG00000065911 ENSG00000128272 ENSG00000285438 PMC4651701__F1 Targeting IL4/IL4R for the treatment of epithelial cancer metastasis ENSG00000105397 ENSG00000169047 ENSG00000198793 ENSG00000113520 ENSG00000131724 ENSG00000105639 PMC4825019__F5 Ingenuity pathway analysis identifies two highly enriched networks for the Tau-interacting proteins ENSG00000062485 PMC4347943__F1 wRAPping up early monocyte and neutrophil recruitment in atherogenesis via AnnexinA1/FPR2 signaling ENSG00000108691 ENSG00000171049 PMC8782720__F8 Proposed model of the role of DAB2IP’s phosphorylation in SAC maintenance and cancer development suppression ENSG00000134982 ENSG00000136848 ENSG00000117399 PMC3588168__F1 Simplified schematic of signaling pathways driving resistance to BRAF inhibitors ENSG00000157764 ENSG00000140443 PMC8472725__F1 Alpha-Synuclein and the Endolysosomal System in Parkinson’s Disease: Guilty by Association ENSG00000102189 ENSG00000005893 PMC6277637__F11 Inflammatory pathways in osteoarthritis ENSG00000152266 ENSG00000125538 PMC7497193__F1 Two major signalling pathways implicated in melanoma ENSG00000157404 ENSG00000198793 ENSG00000146648 ENSG00000101333 ENSG00000196712 PMC6560203__F3 Hydrogen sulfide interaction and effects upon the activity of its biological targets ENSG00000175054 ENSG00000149273 ENSG00000079999 PMC9032563__F1 Mapping Molecular Networks within Clitoria ternatea Linn. against LPS-Induced Neuroinflammation in Microglial Cells, with Molecular Docking and In Vivo Toxicity Assessment in Zebrafish ENSG00000163914 PMC7195008__F1 Pathophysiologic Model of Immunothrombisis in COVID-19 ENSG00000130234 PMC4324508__F1 Microbiota modulation of myeloid cells in cancer therapy ENSG00000175054 ENSG00000239732 ENSG00000111537 ENSG00000189403 ENSG00000136869 ENSG00000139687 ENSG00000026103 PMC9372905__F1 Rare Variants in the Norrin-FZD4 Signaling Pathway and Familial Exudative Vitreoretinopathy (FEVR) With Extraocular Phenotypes ENSG00000124479 ENSG00000162337 ENSG00000106025 ENSG00000134982 ENSG00000174804 ENSG00000168036 PMC5052620__F10 Role of areca nut induced JNK/ATF2/Jun axis in the activation of TGFB pathway in precancerous Oral Submucous Fibrosis ENSG00000177606 ENSG00000137801 PMC2719559__F2 Paracrine and autocrine mechanisms of Akt-mediated tumor-stromal interactions ENSG00000121966 PMC4156720__F1 Cotargeting the PI3K/AKT and AR pathways in CRPC ENSG00000198793 PMC6272897__F5 Putative pathway for the inhibition of inflammatory signaling events by AQCA in in vitro inflammatory responses ENSG00000291971 ENSG00000172936 ENSG00000136869 ENSG00000184216 PMC8670943__F1 Chinese Herbal Medicine Alleviates Myocardial Ischemia/Reperfusion Injury by Regulating Endoplasmic Reticulum Stress ENSG00000136457 ENSG00000128272 ENSG00000144895 PMC6233323__F1 Integration of Drosophila and Human Genetics to understand Notch signaling related diseases ENSG00000133961 ENSG00000132964 ENSG00000101752 PMC7753942__F2 Summary of immunopathogenesis in early and late SARS-CoV-2 infections ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000130234 PMC9428632__F4 Roles of glycolysis in osteosarcoma ENSG00000169071 ENSG00000198793 ENSG00000146648 PMC7398066__F2 ABC transporter-related signaling pathways ENSG00000138075 ENSG00000150907 ENSG00000173599 ENSG00000120088 ENSG00000136869 ENSG00000288325 ENSG00000143921 PMC5034715__F4 Metabolomics analysis of hormone-responsive and triple-negative breast cancer cell responses to paclitaxel identify key metabolic differences ENSG00000047849 ENSG00000118777 ENSG00000023839 PMC8377944__F1 Secondary hypertension: An update on the diagnosis and localisation of a pheochromocytoma or paraganglioma ENSG00000141744 PMC9145792__F9 Artonin F Induces the Ubiquitin-Proteasomal Degradation of c-Met and Decreases Akt-mTOR Signaling ENSG00000019991 ENSG00000198793 PMC7601870__F2 Crosstalk between CK2 and signaling pathways (A) regulating fatty acid synthesis or (B) controlled by phospholipases ENSG00000129219 ENSG00000131473 ENSG00000130164 ENSG00000169710 ENSG00000185591 ENSG00000099194 ENSG00000165527 PMC11792405__F3 TSC1-TSC2 complex in ovarian GSCs, Nephron progenitor cells and ISCs ENSG00000281324 ENSG00000134982 ENSG00000136997 ENSG00000183579 ENSG00000168036 PMC9707069__F2 From mesenchymal niches to engineered in vitro model systems: Exploring and exploiting biomechanical regulation of vertebrate hedgehog signalling ENSG00000180447 ENSG00000144857 ENSG00000166813 ENSG00000128602 PMC3684428__F2 IRE1Alpha- and PERK-mediated cell death pathways ENSG00000128272 ENSG00000144895 ENSG00000171791 ENSG00000162772 ENSG00000127191 PMC3684428__F1 The adaptive unfolded protein response (UPR) ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8494682__F1 Increased biosynthesis of acetyl-CoA in the yeast Saccharomyces cerevisiae by overexpression of a deregulated pantothenate kinase gene and engineering of the coenzyme A biosynthetic pathway ENSG00000157554 ENSG00000153989 ENSG00000138621 ENSG00000127125 PMC7854640__F7 Tumour heterogeneity and intercellular networks of nasopharyngeal carcinoma at single cell resolution ENSG00000168329 ENSG00000078081 ENSG00000146648 PMC9441498__F6 Insight into the interplay between mitochondria-regulated cell death and energetic metabolism in osteosarcoma PMC9596393__F4 Understanding the molecular mechanisms of macrophage polarization and metabolic reprogramming in endometriosis: A narrative review PMC2794560__F1 Metabolic pathways of tamoxifen ENSG00000165841 PMC4367126__F1 Induced regulatory T cells in inhibitory microenvironments created by cancer ENSG00000089692 ENSG00000049768 PMC4926327__F7 Mechanism of stimulated VSMC proliferation through the Wnt4/Dvl-1/Beta-catenin signaling pathway ENSG00000162552 ENSG00000134982 ENSG00000168036 ENSG00000157240 PMC5332939__F1 Diagrammatic representation of the EGF signaling pathway ENSG00000146648 PMC3384069__F1 Wnt/Beta-catenin signaling pathway ENSG00000134982 ENSG00000168036 PMC7381619__F1 Crosstalk between noncoding RNAs and ferroptosis: new dawn for overcoming cancer progression ENSG00000182511 ENSG00000189060 ENSG00000145321 ENSG00000079999 PMC11852973__F3 Therapeutic strategies targeting the AIM2 inflammasome in cancer ENSG00000169245 ENSG00000163568 PMC4285816__F6 A pro-inflammatory signalome is constitutively activated by C33Y mutant TNF receptor 1 in TNF receptor-associated periodic syndrome (TRAPS) ENSG00000177606 ENSG00000127191 ENSG00000168610 ENSG00000123268 PMC11852973__F1 Tumor-derived double-stranded DNA (dsDNA), which can be derived by genomic instability, activates AIM2 inflammasome and cGAS-STING signaling pathway ENSG00000164430 ENSG00000163568 PMC3976626__F8 By simultaneously inhibiting CBS activity and inhibiting GOT1, a key enzyme of the malate/aspartate shuttle, AOAA acts as an inducer of ‘synthetic lethality’ in cancer cells ENSG00000125166 PMC7551862__F7 FO promotes bone formation and growth by activating the IGF-1/IGF-1R signaling pathway ENSG00000140443 PMC4255622__F1 Signaling pathways: HN exerts its function through both extracellular receptors and intracellular binding partners ENSG00000132821 ENSG00000154370 ENSG00000242689 ENSG00000168610 PMC3489928__F4 Proposed Reaction Pathway ENSG00000090402 ENSG00000062485 PMC9647168__F1 Modification of phosphoinositides by the Shigella effector IpgD during host cell infection ENSG00000156299 ENSG00000146648 PMC7042182__F8 Sketch map of the signaling axis with the most significant co-expression pattern including YY1 (Yin and Yang 1 Transcription Factor), Hepatitis A Virus Cellular Receptor 2 (HAVCR2) and mTOR signaling pathway ENSG00000100811 ENSG00000135077 ENSG00000170458 ENSG00000198793 ENSG00000168961 PMC11676689__F4 FoxO signaling KEGG pathway; (B) ABC transporters KEGG pathway ENSG00000087095 ENSG00000182712 ENSG00000127528 ENSG00000173208 ENSG00000168610 ENSG00000005471 ENSG00000145604 ENSG00000149311 ENSG00000065833 ENSG00000135776 ENSG00000198576 ENSG00000123374 ENSG00000198125 ENSG00000096717 ENSG00000145782 ENSG00000128513 ENSG00000133027 PMC10488162__F4 The Nrf2 signaling pathway in environmental pollutant-related ovarian aging ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC3071166__F3 Hypothetical scheme of the proposed mechanisms contributing to the induction of tolerance by SIT PMC7092629__F2 Predicted protein-protein interactions in aSyn pathology: hypothesis and bioinformatic analysis ENSG00000288145 ENSG00000164104 ENSG00000177700 ENSG00000163882 ENSG00000164405 ENSG00000005893 ENSG00000149273 ENSG00000109670 ENSG00000103266 ENSG00000143420 ENSG00000110107 ENSG00000164587 ENSG00000158828 ENSG00000100442 ENSG00000010256 ENSG00000132639 ENSG00000008056 ENSG00000177542 ENSG00000161526 ENSG00000069869 ENSG00000004864 ENSG00000116459 ENSG00000184076 ENSG00000144566 ENSG00000108433 ENSG00000166794 ENSG00000144028 ENSG00000181788 ENSG00000140740 ENSG00000136854 ENSG00000196470 ENSG00000185615 ENSG00000143858 ENSG00000004478 ENSG00000159720 ENSG00000150991 ENSG00000152137 ENSG00000197386 ENSG00000189403 ENSG00000291761 ENSG00000178913 ENSG00000169021 ENSG00000161203 ENSG00000156467 ENSG00000114573 ENSG00000102003 ENSG00000117385 ENSG00000196961 ENSG00000100280 ENSG00000163625 ENSG00000292099 ENSG00000064692 PMC10488162__F3 The Nrf2 signaling pathway in age-related ovarian aging ENSG00000181019 ENSG00000178573 ENSG00000134057 ENSG00000167468 ENSG00000096717 PMC2834432__F1 Phosphatidylinositol 3-kinase (PI3K) signaling cascade ENSG00000002330 ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC4009396__F2 microRNAs in cancer ENSG00000124571 ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC2721377__F1 Molecular toll-like receptors (TLRs) of the human gastrointestinal (GI) tract which act as sensors and are the first responders in the major pathway by which the immune system detects infection or damaged tissue ENSG00000226275 ENSG00000170458 ENSG00000187554 ENSG00000177606 ENSG00000136869 PMC7432706__F2 Leptin receptor signaling pathway, and alterations in signaling that characterize various ganglioside-deficient KO mouse models ENSG00000178188 ENSG00000115138 ENSG00000168610 PMC7432706__F1 Biosynthetic pathway of ganglio-series gangliosides ENSG00000135454 ENSG00000158470 ENSG00000115525 ENSG00000148154 PMC6710477__F1 Schematic overview of cytoplasmic 60S subunit assembly ENSG00000168724 ENSG00000140598 ENSG00000169251 ENSG00000041802 ENSG00000185721 ENSG00000149547 ENSG00000242372 PMC10854734__F5 SADS-CoV infection induces apoptosis and complete autophagy ENSG00000101901 ENSG00000132906 ENSG00000177169 ENSG00000126775 ENSG00000198793 ENSG00000168040 ENSG00000064012 PMC8964401__F7 Dynamics and Functional Interplay of Nonhistone Lysine Crotonylome and Ubiquitylome in Vascular Smooth Muscle Cell Phenotypic Remodeling ENSG00000197713 ENSG00000073578 ENSG00000153574 ENSG00000091140 ENSG00000062485 PMC8103580__F1 Targeting programmed cell death in metabolic dysfunction-associated fatty liver disease (MAFLD): a promising new therapy ENSG00000120868 ENSG00000171791 ENSG00000168040 ENSG00000084774 ENSG00000115317 ENSG00000026103 PMC8103580__F4 Targeting programmed cell death in metabolic dysfunction-associated fatty liver disease (MAFLD): a promising new therapy ENSG00000177169 ENSG00000152348 ENSG00000110497 ENSG00000083290 ENSG00000126775 ENSG00000144848 ENSG00000171791 ENSG00000145782 ENSG00000057663 PMC8103580__F3 Targeting programmed cell death in metabolic dysfunction-associated fatty liver disease (MAFLD): a promising new therapy ENSG00000137033 ENSG00000102871 ENSG00000082512 ENSG00000189403 ENSG00000157625 ENSG00000136869 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC7933775__F1 Hippo signaling pathway ENSG00000113645 ENSG00000186575 ENSG00000109321 ENSG00000114978 ENSG00000150457 ENSG00000131023 PMC2956014__F2 Neutrophil apoptosis ENSG00000102871 ENSG00000120868 ENSG00000168040 ENSG00000127191 PMC3565545__F9 BRCA pathway showing the role of BRCA1 in DNA damage response and crosstalk with other biological pathways, notably the P53 pathway.Notes: Double circles indicate complex interactions involving multiple genes ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000111537 ENSG00000115415 ENSG00000197299 ENSG00000166851 ENSG00000095002 ENSG00000123268 ENSG00000156273 PMC8860543__F8 TNFA Antagonizes the Effect of Leptin on Insulin Secretion through FOXO1-Dependent Transcriptional Suppression of LepRb in INS-1 Cells ENSG00000150907 ENSG00000168610 PMC5081415__F4 KEGG analysis of STRING network of C ENSG00000183463 ENSG00000188895 ENSG00000275111 ENSG00000138433 ENSG00000124253 ENSG00000135097 PMC4539002__F1 Proteostasis network (PN) ENSG00000149196 ENSG00000188554 ENSG00000127022 ENSG00000151929 ENSG00000057663 PMC7176878__F2 NFKBIA is involved in the NF‐KB signalling pathway ENSG00000143799 ENSG00000102871 ENSG00000138798 ENSG00000111321 ENSG00000150455 ENSG00000127191 ENSG00000010671 ENSG00000095585 ENSG00000149311 ENSG00000226275 ENSG00000213658 ENSG00000170458 ENSG00000186716 ENSG00000082512 ENSG00000056558 ENSG00000197943 ENSG00000172936 ENSG00000131323 ENSG00000124181 ENSG00000175104 ENSG00000162692 ENSG00000121060 ENSG00000184216 PMC4629839__F1 MTOR pathway ENSG00000169047 ENSG00000198793 ENSG00000284161 ENSG00000164327 ENSG00000087842 PMC3439567__F2 P2 Receptors for Extracellular Nucleotides in the Central Nervous System: Role of P2X7 and P2Y2 Receptor Interactions in Neuroinflammation ENSG00000142192 ENSG00000291971 ENSG00000163914 ENSG00000146648 PMC4523019__F2 Interferon signaling upstream regulator pathway, with subcellular compartmentalization indicated ENSG00000213928 ENSG00000106785 ENSG00000187608 ENSG00000089127 ENSG00000163739 ENSG00000114737 ENSG00000232326 ENSG00000168961 ENSG00000135899 ENSG00000173369 ENSG00000134321 ENSG00000188313 ENSG00000078081 ENSG00000138755 ENSG00000141753 ENSG00000135116 ENSG00000104081 ENSG00000187678 ENSG00000164342 ENSG00000087245 ENSG00000117228 ENSG00000184979 ENSG00000128284 ENSG00000059378 ENSG00000142089 ENSG00000291555 ENSG00000111331 ENSG00000128965 PMC8513137__F4 Glucagon’s Metabolic Action in Health and Disease ENSG00000288269 ENSG00000170145 ENSG00000124253 ENSG00000160741 PMC3578033__F2 Inflammation and Diabetes-Accelerated Atherosclerosis: Myeloid Cell Mediators ENSG00000151726 ENSG00000023516 ENSG00000173599 ENSG00000108599 ENSG00000105127 PMC3076854__F2 Global transcriptome analysis reveals CB1R-dependent, PHX-induced up-regulation of key cell-cycle proteins ENSG00000105664 ENSG00000138798 ENSG00000291953 PMC8647113__F11 Study of Baicalin toward COVID-19 Treatment: In silico Target Analysis and in vitro Inhibitory Effects on SARS-CoV-2 Proteases ENSG00000169291 ENSG00000002330 ENSG00000070831 ENSG00000173156 ENSG00000124126 ENSG00000113263 PMC8647113__F10 Study of Baicalin toward COVID-19 Treatment: In silico Target Analysis and in vitro Inhibitory Effects on SARS-CoV-2 Proteases ENSG00000180210 ENSG00000142192 ENSG00000101474 ENSG00000069482 ENSG00000170458 ENSG00000102871 ENSG00000175104 ENSG00000127191 ENSG00000135517 ENSG00000026103 PMC2958130__F5 Intertwining Threshold Settings, Biological Data and Database Knowledge to Optimize the Selection of Differentially Expressed Genes from Microarray ENSG00000154589 ENSG00000170458 ENSG00000136869 ENSG00000100985 ENSG00000162692 ENSG00000175104 PMC8637208__F5 Hepatectomy-Induced Alterations in Hepatic Perfusion and Function - Toward Multi-Scale Computational Modeling for a Better Prediction of Post-hepatectomy Liver Function ENSG00000010810 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC10674800__F6 Transcriptomics and Physiological Analyses Reveal Changes in Paclitaxel Production and Physiological Properties in Taxus cuspidata Suspension Cells in Response to Elicitors ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC11242595__F2 TGFB Modulated Pathways in Colorectal Cancer: New Potential Therapeutic Opportunities ENSG00000291971 ENSG00000253352 ENSG00000175104 ENSG00000168610 PMC8304794__F5 Transcriptomic Profiling of Femoral Veins in Deep Vein Thrombosis in a Porcine Model ENSG00000142192 ENSG00000023734 ENSG00000226275 PMC3517905__F1 Summary of the signaling pathways of PKMζ-mediated late-LTP ENSG00000127445 ENSG00000067606 ENSG00000198793 PMC3923158__F2 Components that determine the establishment and tolerance-inducing capacity of tolerogenic effector DCs ENSG00000146469 ENSG00000168610 ENSG00000026103 PMC1856765__F7 Apoptosis of T cells and the control of inflammatory bowel disease: therapeutic implications ENSG00000168040 ENSG00000062485 PMC8504858__F2 Inductive Materials for Regenerative Engineering ENSG00000170365 ENSG00000137834 ENSG00000134982 ENSG00000167941 ENSG00000168036 ENSG00000128602 ENSG00000137845 PMC8874480__F2 JAK2 in Myeloproliferative Neoplasms: Still a Protagonist ENSG00000117400 ENSG00000168610 PMC3814363__F4 Structure-based phylogenetic tree of ATPase enzymes ENSG00000109911 ENSG00000163914 ENSG00000198356 ENSG00000151611 ENSG00000100206 ENSG00000001626 PMC6278419__F5 PPI network and module analysis ENSG00000134982 ENSG00000145192 ENSG00000122194 ENSG00000171560 ENSG00000106927 ENSG00000163631 PMC3583555__F1 Simple model for regulation of breast cancer initiating cells (BT-IC) self-renewal in breast cancer ENSG00000168283 ENSG00000128602 PMC9687165__F3 Self-Renewal of Macrophages: Tumor-Released Factors and Signaling Pathways ENSG00000182578 ENSG00000204103 ENSG00000096717 ENSG00000136826 PMC1856765__F3 Apoptosis of T cells and the control of inflammatory bowel disease: therapeutic implications ENSG00000168040 ENSG00000026103 PMC3583555__F2 Regulation of apoptosis by several pathways ENSG00000114993 ENSG00000259207 PMC3433902__F5 Immune response to phagosome in antigen presentation network pathway map associated with the proteins identified as differentially regulated during zebrafish caudal fin regeneration ENSG00000095585 ENSG00000019582 ENSG00000157782 ENSG00000213658 ENSG00000149269 ENSG00000006451 ENSG00000165527 ENSG00000099942 ENSG00000132693 PMC7483256__F2 Small-molecule drug repurposing to target DNA damage repair and response pathways ENSG00000012061 ENSG00000187790 ENSG00000131944 ENSG00000105486 ENSG00000134574 ENSG00000132646 ENSG00000167986 ENSG00000051180 ENSG00000276787 ENSG00000177084 ENSG00000095002 ENSG00000136936 ENSG00000122512 PMC8471347__F3 NFKB Nucleolar Stress Response Pathway ENSG00000101751 ENSG00000135446 ENSG00000173039 ENSG00000166169 PMC8471347__F1 NFKB Nucleolar Stress Response Pathway ENSG00000173163 ENSG00000173039 PMC7580254__F9 Schematic diagram representing the role of Bruton's tyrosine kinase (BTK) in the pathophysiology of sepsis ENSG00000163739 ENSG00000125538 ENSG00000010671 PMC7483256__F3 Small-molecule drug repurposing to target DNA damage repair and response pathways ENSG00000149311 ENSG00000012048 ENSG00000165392 ENSG00000197299 ENSG00000051180 ENSG00000178966 ENSG00000177084 ENSG00000139618 PMC12210561__F2 Gln modulates multiple signalling pathways to regulate cancer cell proliferation ENSG00000142627 ENSG00000146648 ENSG00000131023 ENSG00000070669 ENSG00000115419 PMC7425451__F5 Downregulation of miR-135a on RAB1B and the RAS signaling pathway in NSCLC cell progression ENSG00000174903 PMC7297132__F1 Characteristics of astrocyte senescence ENSG00000188486 ENSG00000189403 ENSG00000131095 PMC7346762__F2 TrkB signaling-mediated cell survival and the Nrf2-ARE antioxidant system ENSG00000178573 PMC8234271__F2 MAPK/ERK Signaling Pathway in Hepatocellular Carcinoma ENSG00000157404 ENSG00000157764 ENSG00000065361 ENSG00000115904 ENSG00000047936 ENSG00000169032 ENSG00000179295 ENSG00000122025 ENSG00000066468 ENSG00000110395 ENSG00000160867 ENSG00000134853 ENSG00000143622 ENSG00000077782 ENSG00000146648 ENSG00000178568 ENSG00000196712 ENSG00000140443 PMC8234271__F1 MAPK/ERK Signaling Pathway in Hepatocellular Carcinoma ENSG00000157404 ENSG00000146648 PMC10340761__F4 Gene interaction pathways and their regulation in cancer ENSG00000185633 PMC8069355__F3 Speculative model of theta-mediated end joining (TMEJ)/Polθ activity as back-up repair of DSB in homologous recombination (HR) deficient cells ENSG00000012048 ENSG00000051180 ENSG00000177084 PMC6629462__F1 Transport processes and regulatory mechanisms in A- and B- and non-A, non-B IC ENSG00000140519 ENSG00000173599 ENSG00000132677 PMC6027519__F2 Regulation of innate and adaptive immunity by hypoxia and HIF signaling pathway ENSG00000154059 ENSG00000169429 PMC11058607__F2 Pathways in HNSCC cells involving growth factor receptors like TGFB causing cell migration and invasion leading to metastasis ENSG00000198793 ENSG00000135341 PMC7048923__F6 PPI network of “drug-compound-target-pathway” of cinobufotalin injection for lung cancer ENSG00000188641 ENSG00000167601 ENSG00000157404 ENSG00000291971 ENSG00000198793 ENSG00000087586 ENSG00000181555 ENSG00000171791 ENSG00000121879 ENSG00000164305 ENSG00000183765 ENSG00000122025 ENSG00000277571 ENSG00000134086 ENSG00000082175 ENSG00000196549 ENSG00000128052 ENSG00000087245 ENSG00000196839 ENSG00000164120 ENSG00000073756 ENSG00000132170 ENSG00000189283 ENSG00000066468 ENSG00000120899 ENSG00000164362 ENSG00000151617 ENSG00000005381 PMC8847160__F1 Ferroptosis in Rheumatoid Arthritis: A Potential Therapeutic Strategy ENSG00000167468 PMC7763058__F1 TGFB signaling in fibroblasts ENSG00000163914 ENSG00000182541 PMC3857155__F1 Basic depiction of the classical view of the PI3K signaling network (black arrows) as well as the novel signaling pathway revealed in the study by Tan et al ENSG00000198793 ENSG00000136997 ENSG00000166851 PMC6343466__F1 The rationale for Janus kinase inhibitors for the treatment of spondyloarthritis ENSG00000105397 ENSG00000105639 PMC4111858__F5 Two-step model for OR-instructed axonal projection of OSNs ENSG00000114554 ENSG00000126259 ENSG00000149571 PMC7969115__F3 Biomarkers play role in pathology of OA by multiple signaling pathways including NFKB pathway, MAPK pathway, Wnt-signaling pathway, and TLR pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000136869 ENSG00000100985 ENSG00000162692 PMC5854644__F9 MicroRNAs (miRNAs) related to the epigenetic control of genes involved in demyelination, epithelial–mesenchymal transition (EMT), inflammation, pain, and loss of sensation were differentially expressed in leprosy patient (LP) ENSG00000163399 ENSG00000169554 ENSG00000037965 ENSG00000105329 ENSG00000070831 ENSG00000067900 ENSG00000100146 ENSG00000081189 ENSG00000260027 ENSG00000125398 ENSG00000177606 ENSG00000147955 ENSG00000019549 ENSG00000026508 ENSG00000112851 ENSG00000120075 ENSG00000196689 PMC8394875__F3 Ovarian Cancer and Cancer Stem Cells—Cellular and Molecular Characteristics, Signaling Pathways, and Usefulness as a Diagnostic Tool in Medicine and Oncology ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000133067 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000168646 PMC10944252__F2 Enrichment analysis of KEGG signaling pathway, hub gene screening and PPI network analysis based on Genemania database ENSG00000131469 ENSG00000116898 ENSG00000166441 ENSG00000165733 ENSG00000145912 ENSG00000283018 ENSG00000143314 ENSG00000167658 ENSG00000138326 ENSG00000126749 ENSG00000170515 ENSG00000134987 PMC9142523__F7 Adipokine human Resistin promotes obesity-associated inflammatory intervertebral disc degeneration via pro-inflammatory cytokine cascade activation ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC3349963__F1 Canonical and non-canonical IL-13 signaling in cells ENSG00000105397 ENSG00000131724 ENSG00000168610 PMC3001886__F5 Coxiella burnetii, the Agent of Q Fever, Replicates within Trophoblasts and Induces a Unique Transcriptional Response ENSG00000142192 ENSG00000123496 ENSG00000111537 ENSG00000105329 ENSG00000148926 ENSG00000113520 ENSG00000168610 PMC11274159__F2 EBV-affected signaling pathways associated with ferroptosis ENSG00000168003 ENSG00000138449 ENSG00000151012 ENSG00000197635 ENSG00000144554 ENSG00000066044 ENSG00000167468 ENSG00000162772 ENSG00000124762 ENSG00000127948 PMC7093293__F4 Role of Rho/Rho-kinase pathway in the pathogenesis of cardiovascular diseases ENSG00000163914 ENSG00000220205 PMC8394875__F4 Ovarian Cancer and Cancer Stem Cells—Cellular and Molecular Characteristics, Signaling Pathways, and Usefulness as a Diagnostic Tool in Medicine and Oncology ENSG00000168283 ENSG00000136997 ENSG00000026508 PMC1526619__F1 Wnt/Beta-catenin signaling pathway ENSG00000134982 ENSG00000168036 ENSG00000125084 PMC1526619__F2 The canonical transforming growth factor (TGF)B/Smad signaling pathway PMC33831__F1 The branch of the flavonoid pathway for the synthesis of flavones in maize ENSG00000166278 PMC4349862__F6 Overexpression of the Transcription Factor Sp1 Activates the OAS-RNAse L-RIG-I Pathway ENSG00000088888 ENSG00000135828 PMC8127782__F4 Canine Parvovirus and Its Non-Structural Gene 1 as Oncolytic Agents: Mechanism of Action and Induction of Anti-Tumor Immune Response ENSG00000120868 ENSG00000171791 PMC6359724__F1 Oxygen- and hydroxylase-dependent mechanisms regulating hypoxia-inducible factor 1 (HIF-1) activity ENSG00000136878 PMC9360036__F7 Proposed model of MAP4K4 and STRN3 regulation of cell migration and proliferation in MB ENSG00000196792 PMC7824611__F4 Diphthamide synthesis and ADP-ribosylation ENSG00000154813 ENSG00000167658 ENSG00000108963 PMC6359724__F2 HIF-1-dependent reprogramming of the glucose metabolic pathway, and resultant radioresistance ENSG00000136997 PMC7838823__F4 Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses ENSG00000118058 ENSG00000100811 ENSG00000100906 ENSG00000060982 ENSG00000196839 ENSG00000127955 ENSG00000176105 ENSG00000170425 ENSG00000168610 ENSG00000117020 ENSG00000112242 ENSG00000291814 ENSG00000177606 ENSG00000136997 ENSG00000135250 PMC7824611__F5 Proposed model of Cholix-induced cell death pathways ENSG00000140564 ENSG00000167658 ENSG00000067900 PMC6813369__F2 Proposed role of the immunogenic cell death in pemphigus foliaceus ENSG00000198053 ENSG00000105656 PMC6995557__F5 Schematic diagram of the proposed mechanisms by which betulinic acid ameliorates T-2-toxin-induced oxidative stress and diminishes T-2-toxin-induced apoptosis via the JAK2/STAT3 and BAX/BCL-2/caspase-3 pathways PMC6255967__F4 Canonical IRF5 signaling pathway and its negative regulation ENSG00000132109 ENSG00000137265 ENSG00000170145 ENSG00000172936 ENSG00000140577 ENSG00000175104 PMC7345582__F3 Oncogene miRs that activate the STAT3 signaling pathway and promote the proliferation and invasion of GC cells ENSG00000120833 ENSG00000136997 ENSG00000180008 ENSG00000168610 ENSG00000142166 PMC7345582__F2 Onco-suppressor microRNAs in the inhibition of STAT3 and the malignant behavior of gastric cancer cells ENSG00000122691 ENSG00000168610 PMC7345582__F5 STAT3 signaling pathway as an oncogene factor in GC cells ENSG00000177575 ENSG00000026508 ENSG00000168610 PMC5003917__F2 Aberrations in the cyclic AMP-dependent signaling pathway in adrenocortical tumors ENSG00000133895 ENSG00000140691 ENSG00000185231 ENSG00000128655 ENSG00000168036 PMC11490128__F7 Schematic model delineating the mechanisms of SEC14L3 in ccRCC ENSG00000109320 ENSG00000149273 PMC7345582__F4 Long non-coding RNAs and their downstream targets in the regulation of the STAT3 signaling pathway in GC cells ENSG00000168610 PMC7563732__F4 Enzymes from the purine salvage cycles identified in the L ENSG00000137198 ENSG00000198931 ENSG00000119125 PMC7960772__F1 Immune environment surrounding a transplanted organ ENSG00000089692 ENSG00000181847 ENSG00000134982 ENSG00000105656 ENSG00000118520 PMC3134325__F1 Action of ErbB receptor ENSG00000163235 ENSG00000138798 PMC5575491__F5 Model of melatonin regulation of bone mass ENSG00000129167 PMC8924487__F1 Extracellular Vesicles in Systemic Lupus Erythematosus ENSG00000178860 ENSG00000085117 ENSG00000005893 ENSG00000185591 ENSG00000175104 PMC6896143__F4 A diagrammatic representation of the pathways that can indirectly lead to inhibition of apoptosis in a cancer cell ENSG00000019991 ENSG00000168036 ENSG00000168610 PMC3418714__F3 Kinase inhibitors in CLL ENSG00000095585 ENSG00000186716 ENSG00000010671 PMC3418714__F2 Integrin signaling in CLL ENSG00000095585 ENSG00000186716 ENSG00000010671 PMC3564018__F7 Transcription factors predicted to be inhibited by battlefield-like stressors and their targets among stress-modulated genes ENSG00000104856 ENSG00000105369 ENSG00000115008 ENSG00000109320 ENSG00000163739 ENSG00000170558 ENSG00000173039 ENSG00000170606 ENSG00000273686 ENSG00000081051 ENSG00000163737 ENSG00000125347 ENSG00000276561 ENSG00000124762 ENSG00000019582 ENSG00000150782 ENSG00000100241 ENSG00000175899 ENSG00000026508 ENSG00000277263 ENSG00000189403 ENSG00000126353 ENSG00000173846 ENSG00000108821 PMC6527602__F2 ERM structure and function in immune cells ENSG00000180210 ENSG00000117525 ENSG00000107562 ENSG00000291971 ENSG00000121058 PMC12097394__F2 TLR/NFKB mediated inflammatory signaling and involvement of E3 and DUBs ENSG00000164164 ENSG00000125538 ENSG00000121067 ENSG00000172936 ENSG00000150455 ENSG00000162601 ENSG00000175104 PMC3418714__F1 B-cell receptor signaling in CLL ENSG00000095585 ENSG00000010810 ENSG00000197943 ENSG00000010671 PMC12097394__F4 Involvement of E3 ligases and DUBs in calcium handling ENSG00000110395 ENSG00000198626 ENSG00000155313 PMC12097394__F3 Extrinsic and intrinsic apoptosis signaling pathway and involvement of E3 and DUBs ENSG00000162402 ENSG00000102871 ENSG00000120868 ENSG00000168040 ENSG00000273820 PMC7097917__F1 L-serine synthesis pathway ENSG00000284320 ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC10746942__F2 The function of SAMMSON in different cancers ENSG00000151376 ENSG00000178585 ENSG00000185591 PMC10746942__F1 SAMMSON via different mechanisms exerts its oncogenic roles in melanoma ENSG00000138380 PMC5955117__F6 p53 and metabolism: from mechanism to therapeutics ENSG00000198793 ENSG00000078237 PMC12005349__F1 Signalling scheme of the TGFB‐SMAD signalling pathway ENSG00000170365 PMC8981989__F2 Glucose, Fatty Acid and Amino Acid Metabolism by Ubiquitination and SUMOylation for Cancer Progression ENSG00000154370 ENSG00000132109 ENSG00000079387 ENSG00000124422 ENSG00000103266 ENSG00000155827 ENSG00000134982 ENSG00000142230 ENSG00000126261 ENSG00000134086 ENSG00000074800 ENSG00000175104 ENSG00000188612 ENSG00000277276 PMC5955117__F1 P53 regulates critical points in cell signaling and metabolism ENSG00000135423 ENSG00000092621 ENSG00000078237 ENSG00000284194 PMC6643298__F9 The conclusion of the results in this study ENSG00000173599 ENSG00000111666 PMC4355577__F2 Cancer Stem Cell Niche: How Essential is the Niche in Regulating Stemness of Tumor Cells? ENSG00000178860 ENSG00000019991 ENSG00000087245 ENSG00000107562 ENSG00000041982 ENSG00000149968 ENSG00000113520 ENSG00000166670 ENSG00000100985 ENSG00000112715 PMC10918892__F5 Schematic diagram illustrating the role of miR-223-3p on NLRP3 inflammasome signaling pathway in LPS-induced HTR8/SVneo cells ENSG00000278718 ENSG00000162711 ENSG00000172936 ENSG00000136869 PMC9327246__F8 d-Borneol enhances cisplatin sensitivity via p21/p27-mediated S-phase arrest and cell apoptosis in non-small cell lung cancer cells and a murine xenograft model ENSG00000123374 ENSG00000105810 ENSG00000184207 PMC6697022__F2 Tyrosine kinases in the development of atopic dermatitis ENSG00000186716 ENSG00000145777 ENSG00000105639 PMC5745276__F2B Non-Canonical Wnt Pathway and the Notch and Sonic Hedgehog Pathway-The two major non-canonical pathways are Wnt/calcium and Planar Cell Polarity (PCP) pathways ENSG00000168036 ENSG00000114315 ENSG00000128602 PMC5745276__F2A Canonical Wnt Pathway and Inhibitors of the Wnt/beta-Catenin Signaling Pathway ENSG00000134982 ENSG00000229894 ENSG00000168036 ENSG00000154310 PMC8110204__F2 Sirtuin-1 in Immune Response and Systemic Lupus Erythematosus ENSG00000029363 ENSG00000150782 ENSG00000145839 ENSG00000198793 ENSG00000189403 ENSG00000172936 ENSG00000049768 ENSG00000096717 ENSG00000168610 PMC8329528__F1 Branched-chain Amino Acids: Catabolism in Skeletal Muscle and Implications for Muscle and Whole-body Metabolism ENSG00000177169 ENSG00000177058 ENSG00000169047 PMC4621929__F3 STRING network analysis reveals a database of known and predicted protein interactions ENSG00000006607 ENSG00000077235 ENSG00000291971 ENSG00000138798 ENSG00000197150 ENSG00000115816 ENSG00000076003 ENSG00000123552 ENSG00000157890 ENSG00000187957 ENSG00000108830 ENSG00000178573 ENSG00000176396 ENSG00000213024 ENSG00000172530 ENSG00000101333 ENSG00000138795 ENSG00000067900 ENSG00000043462 ENSG00000162591 ENSG00000127334 ENSG00000276043 ENSG00000101082 ENSG00000111145 ENSG00000106780 ENSG00000198855 ENSG00000013810 ENSG00000105429 ENSG00000112232 ENSG00000143126 ENSG00000012822 ENSG00000175899 ENSG00000146648 ENSG00000023839 PMC5854419__F1 Mitogen-activated protein kinase signaling in plant pathogenic fungi ENSG00000168066 PMC4023360__F1 Role of Heat shock protein-27 (HSP27) and clusterin (CLU) in cancer cell survival ENSG00000002330 ENSG00000120885 ENSG00000140443 ENSG00000026103 PMC5545725__F4 Proposed model of dopamine dysregulation in the nigrostriatal pathway in schizophrenia ENSG00000149295 PMC3994501__F9 Signaling pathways for LTM formation upon associative olfactory conditioning of honeybees ENSG00000063180 ENSG00000062485 PMC3633862__F6 Interferon-Beta Induces Distinct Gene Expression Response Patterns in Human Monocytes versus T cells ENSG00000213928 ENSG00000070831 ENSG00000089127 ENSG00000157601 ENSG00000185885 ENSG00000230034 ENSG00000068079 ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000163914 ENSG00000189403 ENSG00000136869 ENSG00000185591 ENSG00000162692 PMC7532351__F4 Signalling Pathway Underlying PAK1-Blockers and Viral Infections ENSG00000108691 ENSG00000130234 ENSG00000149269 PMC11599025__F1 Innate immune responses against ASFV infection ENSG00000162711 ENSG00000213928 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000136869 ENSG00000131323 ENSG00000164342 PMC5351205__F1 Sub-pathway enrichment analysis of differentially expressed genes (DEGs) ENSG00000117054 ENSG00000111058 ENSG00000114054 ENSG00000124370 ENSG00000163541 PMC5847475__F2 Mechanism of PD-1 and PDL-1 pathway in tumor environment and the complex crosstalk between cancer, tumor, T-cell, APC and macrophage and tumor stroma ENSG00000019991 ENSG00000134982 ENSG00000174136 PMC6838750__F2 Main processes involved in exercise-induced and neurotrophin-mediated increased viability of dopaminergic neurons ENSG00000171791 PMC10778705__F3 cGAS-STING antitumoral and protumoral mechanisms ENSG00000183735 ENSG00000164430 ENSG00000059378 ENSG00000168610 PMC11625754__F4 Effect of AB on the NMJ formation process ENSG00000142192 ENSG00000134569 ENSG00000030304 PMC10374777__F2 Molecular mechanism of ferulic acid and its derivatives in tumor progression ENSG00000135446 ENSG00000132646 ENSG00000198793 ENSG00000123374 ENSG00000105810 PMC11667055__F6 Peroxiredoxin 1-Toll-like receptor 4-p65 axis inhibits receptor activator of nuclear factor kappa-B ligand-mediated osteoclast differentiation ENSG00000102794 ENSG00000136869 ENSG00000131196 PMC9181281__F10 Artemisinin Attenuates Amyloid-Induced Brain Inflammation and Memory Impairments by Modulating TLR4/NFKB Signaling ENSG00000136869 PMC7327948__F3 Diagram describing the possibility for Roflumilast to increase DCX and MAP2 expression ENSG00000077279 PMC6351175__F7 Hypothesized regulatory relationships between TGFB, Tgif1, miR‐18a, and NeuroD during photoreceptor differentiation ENSG00000177426 PMC2869029__F1 Regulation of macrophage function in tumors: the multifaceted role of NFKB ENSG00000169245 ENSG00000081181 ENSG00000125538 ENSG00000172936 ENSG00000118520 ENSG00000125347 ENSG00000168610 ENSG00000276561 ENSG00000142166 PMC8143176__F1 Store-Operated Calcium Entry: Shaping the Transcriptional and Epigenetic Landscape in Pancreatic Cancer ENSG00000284774 PMC8323226__F5 Exosome-derived noncoding RNAs in gastric cancer: functions and clinical applications ENSG00000177575 PMC7131993__F1 Increased matrix stiffness can affect cells in different signaling pathways in colorectal cancer (CRC) ENSG00000281324 ENSG00000162337 ENSG00000291971 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC11484773__F2 Schematic diagram illustrating the interaction between neuroinflammation and microglial activation, as well as a separate schematic diagram depicting the TREM2 signaling pathway ENSG00000137845 PMC5522997__F9 Representative gene networks that were significantly regulated (P < 0.05 with the Fisher's exact test) in response to cocaine in WT compared to SERT Met172 mice ENSG00000198918 ENSG00000137601 ENSG00000168702 ENSG00000110799 ENSG00000108551 ENSG00000157193 ENSG00000249992 ENSG00000169116 ENSG00000163171 ENSG00000137941 ENSG00000144285 ENSG00000111262 ENSG00000196090 ENSG00000198626 ENSG00000145592 ENSG00000157106 ENSG00000130037 ENSG00000277586 ENSG00000108797 ENSG00000133124 ENSG00000291834 ENSG00000111785 ENSG00000127588 ENSG00000132164 ENSG00000170340 ENSG00000069966 PMC10152446__F7 Structure Elucidation and Biosynthesis of Nannosterols A and B, Myxobacterial Sterols from Nannocystis sp. MNa10993 ENSG00000110921 ENSG00000116133 ENSG00000172893 ENSG00000197429 PMC7851492__F1 Conflicting metabolic alterations in CSCs ENSG00000136997 PMC5549772__F2 Salmonella enterica serovar-specific transcriptional reprogramming of infected cells ENSG00000213928 ENSG00000105835 ENSG00000187608 ENSG00000148926 ENSG00000162772 ENSG00000288411 ENSG00000041982 ENSG00000163734 ENSG00000196639 ENSG00000023445 ENSG00000117228 ENSG00000204103 ENSG00000125148 ENSG00000143878 ENSG00000185745 ENSG00000221869 ENSG00000116741 ENSG00000185885 ENSG00000164176 ENSG00000125347 ENSG00000169245 ENSG00000118503 ENSG00000143507 ENSG00000134070 ENSG00000115009 ENSG00000104856 ENSG00000120833 ENSG00000102962 ENSG00000169248 ENSG00000152661 ENSG00000114737 ENSG00000087085 ENSG00000127129 ENSG00000011422 ENSG00000145623 ENSG00000140379 ENSG00000146072 ENSG00000125538 ENSG00000056558 ENSG00000108688 ENSG00000146678 ENSG00000128342 ENSG00000171560 ENSG00000081041 ENSG00000115008 ENSG00000259207 ENSG00000100906 ENSG00000115267 ENSG00000130589 ENSG00000188710 ENSG00000164171 ENSG00000169242 ENSG00000073756 ENSG00000168610 ENSG00000172183 ENSG00000167772 ENSG00000108691 ENSG00000186716 ENSG00000177606 ENSG00000135114 ENSG00000114268 PMC6944711__F3 Functional intersection of the GPCR-senescence system ENSG00000178573 ENSG00000177606 ENSG00000288263 PMC3480664__F1 Neurotrophin Regulation of Energy Balance in the Adult CNS and PNS ENSG00000242689 ENSG00000198576 ENSG00000115138 PMC8666469__F3 Baricitinib combination therapy: a narrative review of repurposed Janus kinase inhibitor against severe SARS-CoV-2 infection ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000138798 ENSG00000168610 ENSG00000142224 PMC3118279__F2 Ingenuity Pathway Analysis of epidermal genetic information retrieval-harvested melanoma specimens identifies overexpressed genes involved in melanocyte development and pigmentation ENSG00000157404 ENSG00000291971 ENSG00000135903 ENSG00000171791 ENSG00000100146 PMC4426221__F2 Schematic summary graph shows the postsynaptic effects of mGluR2/3 agonists on the regulation of both AMPA and NMDA receptors ENSG00000291971 ENSG00000132639 PMC8098721__F1 Canonical and non-canonical Wnt signaling pathways ENSG00000156076 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000155011 ENSG00000050165 ENSG00000104371 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000185269 PMC6305219__F1 Cdon, Boc, and Gas1 act as positive regulators of Shh signaling during optic vesicle formation ENSG00000064309 ENSG00000180447 ENSG00000144857 ENSG00000164690 ENSG00000128602 PMC6915081__F7 The possible mechanism of sotetsuflavone inhibited progression of non-small cell lung cancer ENSG00000198793 ENSG00000057663 PMC11693700__F8 Key proteins in the HIF, ferroptosis, PI3K/AKT/mTOR, and p53 signaling pathways are subjected to ubiquitination modifications by deubiquitinases and E3 ubiquitin ligases ENSG00000163930 ENSG00000134086 ENSG00000125826 ENSG00000165312 ENSG00000109189 ENSG00000135913 ENSG00000167468 ENSG00000198793 ENSG00000086991 ENSG00000132481 ENSG00000109670 PMC11693700__F7 Deubiquitylase in the p53 signaling pathway signaling pathway ENSG00000125826 ENSG00000198793 ENSG00000132481 PMC11693700__F6 Deubiquitylase in the PI3K/AKT/mTOR signaling pathway signaling pathway ENSG00000134086 ENSG00000163818 ENSG00000165312 ENSG00000109189 ENSG00000103257 ENSG00000186187 ENSG00000109670 PMC11693700__F5 BAP1 in the Ferroptosis signaling pathway ENSG00000163930 ENSG00000134086 ENSG00000151012 ENSG00000167468 PMC2815132__F1 Dopamine Synthesis Pathway: Dopamine’s synthesis pathway begins with the amino acid tyrosine and is regulated by the activity of tyrosine hydroyxylase ENSG00000123454 ENSG00000141744 PMC11693700__F4 VHL and Beta-TrCP in the Ferroptosis signaling pathway ENSG00000163930 ENSG00000134086 ENSG00000135913 PMC11693700__F3 BAP1 and USP37 in the HIF signaling pathway ENSG00000086991 ENSG00000135245 ENSG00000134531 PMC3829308__F1 Interferon beta signaling pathway ENSG00000105397 ENSG00000142166 PMC3683326__F3 GenMAPP schematic of cell cycle pathway genes ENSG00000145604 ENSG00000124102 ENSG00000132646 ENSG00000123374 ENSG00000277273 ENSG00000276876 PMC3784533__F1 Emerging concepts in immunity to hepatitis C virus infection ENSG00000169245 ENSG00000183735 ENSG00000088888 ENSG00000130164 ENSG00000105397 ENSG00000110651 ENSG00000131323 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC7798030__F2 p21 is regulated by multiple pathways ENSG00000102226 ENSG00000132646 ENSG00000136826 ENSG00000119147 ENSG00000110693 PMC6545597__F1 Proposed model showing the interactions of Nm23-H1 with cellular pathways ENSG00000070831 ENSG00000163914 ENSG00000152193 PMC6085137__F1 FOXO1 regulates activation and function of dendritic cells ENSG00000150907 ENSG00000198793 ENSG00000164327 ENSG00000126353 PMC3381238__F1 Schematic representation of APP processing and role of its products in AD pathology ENSG00000142192 ENSG00000184634 ENSG00000087085 PMC4990059__F2 Canonical Wnt signalling pathway ENSG00000134982 ENSG00000168036 PMC2783967__F6 Global Gene Expression Analysis Reveals Evidence for Decreased Lipid Biosynthesis and Increased Innate Immunity in Uninvolved Psoriatic Skin ENSG00000057252 ENSG00000151657 ENSG00000119915 ENSG00000095321 ENSG00000151365 ENSG00000186480 ENSG00000169710 ENSG00000179593 ENSG00000203857 ENSG00000069482 ENSG00000134824 ENSG00000149485 ENSG00000134324 PMC10885964__F2 Advancements in Genetic Marker Exploration for Livestock Vertebral Traits with a Focus on China ENSG00000067141 ENSG00000137834 ENSG00000010704 ENSG00000142227 ENSG00000157933 ENSG00000187720 ENSG00000196591 ENSG00000156574 ENSG00000134363 ENSG00000205250 ENSG00000137801 ENSG00000170365 ENSG00000111537 ENSG00000095739 ENSG00000106327 ENSG00000100387 ENSG00000147255 ENSG00000113558 ENSG00000164093 ENSG00000169375 PMC8615223__F1 Immunomodulatory Effects of a Concoction of Natural Bioactive Compounds—Mechanistic Insights ENSG00000181019 ENSG00000198793 ENSG00000164400 ENSG00000113520 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 ENSG00000079999 PMC5505220__F3 Modeled mechanism by which FSH via PKA inhibits MKP3/DUSP6 to promote the accumulation of phosphorylated ERK in preantral GCs ENSG00000146648 PMC8505973__F1 Resistance to Hypomethylating Agents in Myelodysplastic Syndrome and Acute Myeloid Leukemia From Clinical Data and Molecular Mechanism ENSG00000136807 ENSG00000178860 ENSG00000178694 ENSG00000158825 ENSG00000162692 ENSG00000175104 PMC5567910__F8 A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development ENSG00000103241 ENSG00000164690 ENSG00000128602 PMC8615223__F6 Immunomodulatory Effects of a Concoction of Natural Bioactive Compounds—Mechanistic Insights ENSG00000198793 ENSG00000136869 ENSG00000079999 PMC8615223__F5 Immunomodulatory Effects of a Concoction of Natural Bioactive Compounds—Mechanistic Insights ENSG00000002330 ENSG00000135446 ENSG00000123374 ENSG00000120868 ENSG00000105810 ENSG00000171791 ENSG00000168040 ENSG00000026103 PMC8615223__F4 Immunomodulatory Effects of a Concoction of Natural Bioactive Compounds—Mechanistic Insights ENSG00000002330 ENSG00000198793 ENSG00000171791 PMC8615223__F3 Immunomodulatory Effects of a Concoction of Natural Bioactive Compounds—Mechanistic Insights ENSG00000002330 ENSG00000135446 ENSG00000198793 ENSG00000169047 ENSG00000123374 ENSG00000120868 ENSG00000105810 ENSG00000171791 ENSG00000168040 ENSG00000146648 ENSG00000026103 PMC5946330__F7 Proposed role of TGFB1 signaling in HASM cell shortening and hyperresponsiveness ENSG00000166278 PMC6156841__F1 Human Disease Phenome construction ENSG00000178127 ENSG00000139180 ENSG00000142192 ENSG00000143801 ENSG00000073578 ENSG00000205155 ENSG00000158828 ENSG00000110717 ENSG00000064692 ENSG00000115317 PMC10960765__F2 Ubiquitination enzymes in the Wnt/Beta-catenin signaling pathway of CRC ENSG00000118518 ENSG00000134982 ENSG00000137699 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000108106 PMC11545986__F3 Circadian dysregulation of lipid metabolism and adverse pregnancy outcomes ENSG00000132326 ENSG00000198670 PMC7603577__F9 Relaxin signaling pathway in the treatment of gout and hyperuricemia with plantain ENSG00000087245 ENSG00000163235 ENSG00000277069 ENSG00000100985 PMC9540480__F1 Applying Modeling and Simulations for Rational Dose Selection of Novel Toll‐Like Receptor 7/8 Inhibitor Enpatoran for Indications of High Medical Need ENSG00000276561 PMC7603577__F7 IL-17 signaling pathway of plantain in the treatment of gout and hyperuricemia ENSG00000102871 ENSG00000157625 ENSG00000100985 ENSG00000168040 ENSG00000056736 ENSG00000175104 ENSG00000163702 PMC7956553__F3 Simplified cartoon of potential crosstalk between activated canonical Wnt/Beta-catenin and mTORC1 pathways ENSG00000198793 ENSG00000168036 PMC4197875__F2 Hippo signaling pathway in stem cell biology and cancer ENSG00000165556 ENSG00000126016 ENSG00000113196 ENSG00000186575 ENSG00000168036 ENSG00000107485 ENSG00000150457 ENSG00000131023 PMC7956553__F2 Cartoon of major proteins in the wingless-related integration site (Wnt)/Beta-catenin growth pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC4197875__F1 Hippo signaling pathway in stem cell biology and cancer ENSG00000126016 ENSG00000149930 ENSG00000142178 ENSG00000160551 ENSG00000135090 ENSG00000135903 ENSG00000139926 ENSG00000114978 ENSG00000007047 ENSG00000150457 ENSG00000132849 ENSG00000131023 ENSG00000186575 ENSG00000160584 ENSG00000163914 ENSG00000170145 ENSG00000165323 ENSG00000169435 PMC6406015__F1 Regulation of B cell receptor (BCR) signaling on B cell survival ENSG00000177455 ENSG00000105369 ENSG00000002330 ENSG00000007312 ENSG00000186716 ENSG00000152689 ENSG00000171791 ENSG00000112186 ENSG00000010671 ENSG00000198286 PMC7956553__F1 Cartoon of major proteins in the mechanistic target of rapamycin (mTOR) growth pathway PMC5539260__F7 Overview of the pathogenic model of C. difficile infection ENSG00000117335 ENSG00000162924 ENSG00000168077 ENSG00000146648 PMC4197875__F4 Hippo signaling pathway in stem cell biology and cancer ENSG00000042832 ENSG00000168036 PMC11788642__F8 Schema of Rnf111 regulating the development of hematopoietic stem and progenitor cells by maintaining Smad2/3 phosphorylation and activating the Gcsfr/NO signaling pathway ENSG00000172216 PMC4197875__F3 Hippo signaling pathway in stem cell biology and cancer ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC11356930__F5 MEHTCMPs on intestinal flora ENSG00000172936 ENSG00000136869 PMC11356930__F4 MEHTCMPs on the NLRP3 signaling pathway ENSG00000162711 ENSG00000172936 ENSG00000136869 PMC11356930__F3 MEHTCMPs on the MAPK signaling pathway ENSG00000115415 ENSG00000172936 ENSG00000175104 ENSG00000168610 ENSG00000184216 PMC7956553__F4 Cartoon of mTORC1, Wnt/Beta-catenin, and estrogen receptor A (ERA) molecular pathway interplay in the female-specific, Tsc2-null, rare lung disease lymphangioleiomyomatosis (LAM) ENSG00000154342 ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000118971 PMC11356930__F2 MEHTCMPs on the signaling pathway of TLRs ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC8064164__F1 Role of cannabidiol in Parkinson’s disease by targeting the WNT/Beta-catenin pathway, oxidative stress and inflammation ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6746018__F1 PI3K/Ras signaling pathway ENSG00000157764 ENSG00000110395 ENSG00000198793 ENSG00000115904 ENSG00000196712 PMC9139230__F1 How Phosphofructokinase-1 Promotes PI3K and YAP/TAZ in Cancer: Therapeutic Perspectives ENSG00000180210 ENSG00000131473 ENSG00000198793 ENSG00000115904 ENSG00000168036 ENSG00000146648 ENSG00000159399 PMC5539260__F5 Host/pathogen cross-talk mechanism through core pathways at the early stage of C ENSG00000100811 ENSG00000156298 ENSG00000141480 ENSG00000149269 ENSG00000149273 ENSG00000168077 PMC8358930__F1 Biological Significance of YAP/TAZ in Pancreatic Ductal Adenocarcinoma ENSG00000150457 ENSG00000131023 PMC9258583__F8 Determinants of RPA megafoci localization to the nuclear periphery in response to replication stress ENSG00000163624 ENSG00000148204 ENSG00000051180 ENSG00000128908 PMC8874408__F6 3, 3′- (3, 5-DCPBC) Down-Regulates Multiple Phosphokinase Dependent Signal Transduction Pathways in Malignant Melanoma Cells through Specific Diminution of EGFRY1086 Phosphorylation ENSG00000149311 ENSG00000291971 ENSG00000173757 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000168610 ENSG00000146648 PMC9713001__F2 Review of the endocrine organ–like tumor hypothesis of cancer cachexia in pancreatic ductal adenocarcinoma ENSG00000125166 ENSG00000198380 ENSG00000103257 ENSG00000115419 ENSG00000159399 PMC10759355__F1 Helicobacter pylori infection and Parkinson’s Disease: etiology, pathogenesis and levodopa bioavailability ENSG00000172936 ENSG00000136869 ENSG00000038002 PMC5982750__F5 SNPs in predicting clinical efficacy and toxicity of chemotherapy: walking through the quicksand ENSG00000138115 PMC9713001__F4 Review of the endocrine organ–like tumor hypothesis of cancer cachexia in pancreatic ductal adenocarcinoma ENSG00000168003 ENSG00000177169 ENSG00000151012 ENSG00000167468 ENSG00000198793 ENSG00000144848 ENSG00000168610 PMC5982750__F4 SNPs in predicting clinical efficacy and toxicity of chemotherapy: walking through the quicksand ENSG00000172831 ENSG00000134982 ENSG00000262243 PMC9713001__F6 Review of the endocrine organ–like tumor hypothesis of cancer cachexia in pancreatic ductal adenocarcinoma ENSG00000087510 ENSG00000169554 ENSG00000134086 ENSG00000172216 ENSG00000115415 ENSG00000105991 ENSG00000150907 ENSG00000170677 ENSG00000168610 PMC5982750__F1 Fluoropyrimidines pathway ENSG00000188641 PMC9072012__F3 CTNNB1 in Endometrial Cancer ENSG00000134982 ENSG00000168036 PMC3145575__F3 CSR pathways for primary non-HCC hepatocytes and HCC (Huh7) cell types ENSG00000087095 ENSG00000112977 ENSG00000111537 ENSG00000163235 ENSG00000148798 ENSG00000198793 PMC5982750__F3 SNPs in predicting clinical efficacy and toxicity of chemotherapy: walking through the quicksand ENSG00000012061 PMC6019481__F10 Estrogen signaling pathway ENSG00000087245 ENSG00000291971 ENSG00000113070 ENSG00000115904 ENSG00000127955 ENSG00000178363 ENSG00000143933 ENSG00000169032 ENSG00000182621 ENSG00000121879 ENSG00000087460 ENSG00000160691 ENSG00000112038 ENSG00000004478 ENSG00000128272 ENSG00000177606 ENSG00000185591 ENSG00000146648 PMC6122186__F1 Hippo signaling pathway ENSG00000150457 ENSG00000131023 PMC6122186__F2 Simplified illustration of YAP/TAZ and glycolysis ENSG00000176692 ENSG00000147162 ENSG00000159399 PMC2729314__F2 Wnt signaling network ENSG00000281324 ENSG00000134982 ENSG00000163914 ENSG00000148175 ENSG00000168036 PMC5621106__F1 Double-strand break (DSB) repair pathway choice ENSG00000138346 ENSG00000165392 ENSG00000197299 PMC3671630__F1 Nucleotide excision repair ENSG00000012061 ENSG00000134574 ENSG00000132646 ENSG00000163945 ENSG00000167986 ENSG00000177084 ENSG00000136936 ENSG00000122008 PMC7986633__F4 Proposed model of how deflavination of ACAD9 by ECSIT permits the coordinated regulation of the FAO and OXPHOS pathways ENSG00000137806 ENSG00000166278 ENSG00000130159 ENSG00000177646 PMC3109492__F2 Intestinal Effector T Cells in Health and Disease ENSG00000145777 ENSG00000166090 ENSG00000049768 PMC8129117__F6 Proposed model of ROS generation and regulation of survival signals in CLL cells ENSG00000167601 ENSG00000186716 ENSG00000198793 ENSG00000010671 PMC7402427__F8 Summary for nuclear and cytoplasmic roles for EZH2 during osteoclastogenesis ENSG00000204103 ENSG00000198793 PMC1828067__F7 Osteopontin/AvB3 signaling in the regulation of prostate cancer cell migration ENSG00000291971 ENSG00000163914 ENSG00000026508 PMC11824814__F8 Dietary DHA Regulated the Androgen Production in Male Chinese Tongue Sole Cynoglossus semilaevis ENSG00000086696 ENSG00000108786 ENSG00000203857 ENSG00000176387 PMC11491976__F3 PI3K/AKT/mTOR signaling pathway ENSG00000138798 ENSG00000169047 ENSG00000146648 ENSG00000140443 PMC11491976__F2 PI3K and PIP2-mediated pathway ENSG00000198793 ENSG00000124253 PMC4766410__F5 Extracellular calcium-sensing receptor regulates human fetal lung development via CFTR ENSG00000016490 ENSG00000001626 ENSG00000036828 ENSG00000114859 PMC8770601__F2 Effect of oxidized lipids of function of myeloid cells in cancer ENSG00000135218 ENSG00000005381 PMC8770601__F1 Major metabolic pathways leading to the formation of signaling molecules from PUFA-GPL and pGPL ENSG00000133895 ENSG00000005381 PMC7941238__F2 Mechanisms by which ADSCs‐EXOs may promote wound healing ENSG00000138207 ENSG00000149968 ENSG00000170558 ENSG00000132646 PMC4552732__F4 A Biochemical Approach to Understand the Pathogenesis of Advanced Pulmonary Arterial Hypertension: Metabolomic Profiles of Arginine, Sphingosine-1-Phosphate, and Heme of Human Lung ENSG00000164023 ENSG00000171759 ENSG00000188611 ENSG00000172296 ENSG00000035681 PMC6749995__F4 Lung microenvironment: an important regulator of tumour growth and metastasis ENSG00000108691 ENSG00000143546 ENSG00000163220 ENSG00000125538 ENSG00000203710 ENSG00000136869 ENSG00000100985 ENSG00000121807 ENSG00000275565 ENSG00000277943 PMC5571607__F2 DAMP/ TLR/ inflammasome interactions ENSG00000162711 ENSG00000134070 ENSG00000026508 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC6503994__F8 Potential role for TXNIP in HG-mediated RPE dysfunction ENSG00000162711 ENSG00000197713 ENSG00000265972 PMC5395201__F3 Inactivation of Retinoblastoma Protein in Uveal Melanoma by Phosphorylation of Sites in the COOH-Terminal Region ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC5824774__F5 Result of ‘Networks’ query way ENSG00000084093 ENSG00000103266 ENSG00000063978 ENSG00000065361 ENSG00000143878 ENSG00000105401 ENSG00000138798 ENSG00000158458 ENSG00000160182 ENSG00000160181 ENSG00000187764 ENSG00000169032 ENSG00000166266 ENSG00000169752 ENSG00000160691 ENSG00000213658 ENSG00000163235 ENSG00000124882 ENSG00000172602 ENSG00000136997 ENSG00000112851 ENSG00000146648 ENSG00000178568 PMC7527574__F1 Therapeutic targeting of HGF/c-Met pathway ENSG00000167601 ENSG00000019991 ENSG00000002330 ENSG00000291971 ENSG00000198793 PMC8144308__F1 Reciprocal Relationship Between Calcium Signaling and Circadian Clocks: Implications for Calcium Homeostasis, Clock Function, and Therapeutics ENSG00000069667 PMC8012701__F2 Lipid metabolisms change in dormant cancer cells ENSG00000007944 ENSG00000143815 ENSG00000149809 ENSG00000113161 ENSG00000099194 ENSG00000005187 ENSG00000052802 ENSG00000198911 PMC4576413__F3 Redox control of protein degradation ENSG00000134086 ENSG00000100387 ENSG00000125538 ENSG00000079999 PMC3983080__F1 Multiple Model-Informed Open-Loop Control of Uncertain Intracellular Signaling Dynamics ENSG00000291603 ENSG00000213658 ENSG00000113263 ENSG00000124181 PMC6108937__F3 Androgen receptor signaling R promotes diverse metabolic processes ENSG00000131473 ENSG00000169710 PMC2576041__F9 The role of the IGF-1/phosphatidylinositol 3-kinase (PI3K)/Akt pathway and atrogin-1 and MuRF-1 in SI-induced atrophy and in the amelioration of atrophy by high-load isometric contractions ENSG00000090402 ENSG00000169047 ENSG00000198793 PMC1574111__F3 Proposed mechanism for FK506-potentiated neurite outgrowth ENSG00000070831 PMC8144308__F2 Reciprocal Relationship Between Calcium Signaling and Circadian Clocks: Implications for Calcium Homeostasis, Clock Function, and Therapeutics ENSG00000159200 PMC6788940__F2 Targetable pathways in ESR1 mutant cells identified in preclinical studies ENSG00000198793 ENSG00000123374 ENSG00000277273 ENSG00000140443 PMC9406846__F2 Clinical and Molecular Implications of Osteopontin in Heart Failure ENSG00000197444 ENSG00000026508 PMC5940273__F3 Repressing the repressor: Ezh2 mediates macrophage activation ENSG00000172936 ENSG00000175104 PMC6500576__F2 Melanocortin pathway and control of appetite- progress and therapeutic implications ENSG00000104044 ENSG00000150907 ENSG00000067900 ENSG00000072315 ENSG00000168610 PMC6675248__F1 Various molecular inhibitors and stimulators in mTOR signalling pathway ENSG00000101407 ENSG00000163914 ENSG00000118515 ENSG00000155792 ENSG00000112561 ENSG00000196712 PMC6675248__F3 Role of mTOR signalling pathway during protein translation ENSG00000163435 ENSG00000198793 PMC6675248__F2 Cell signalling dysfunction in mTOR signalling pathway leading to syndromic and idiopathic autism ENSG00000187840 ENSG00000196712 PMC9390702__F1 Targeting KRAS: Crossroads of Signaling and Immune Inhibition ENSG00000135446 ENSG00000198793 ENSG00000115904 ENSG00000105810 ENSG00000146648 PMC7541823__F5 Pathway of phagosome biogenesis, maturation, and phagolysosome fusion for efficient clearance of Mtb ENSG00000003056 ENSG00000102189 ENSG00000123576 ENSG00000100330 ENSG00000135404 ENSG00000165527 ENSG00000119383 ENSG00000274145 PMC7541823__F1 Receptors implicated in the internalisation of Mycobacterium sp ENSG00000162711 ENSG00000239732 ENSG00000135218 ENSG00000167207 ENSG00000170458 ENSG00000134982 ENSG00000163568 ENSG00000163565 ENSG00000203710 ENSG00000105656 ENSG00000164342 PMC10963452__F4 Schematic plots illustrate the signaling mechanism of other organokines in intervertebral disc cells ENSG00000167772 ENSG00000130173 ENSG00000163430 ENSG00000178573 ENSG00000198793 ENSG00000112561 ENSG00000121853 ENSG00000079999 PMC4788929__F6 MELK and stathmin signaling ENSG00000169291 PMC10963452__F3 Schematic plots illustrate the signaling mechanism of various osteokines in intervertebral disc cells ENSG00000163464 ENSG00000113140 ENSG00000168036 ENSG00000164690 PMC6054915__F6 Engineered MBP-specific human Tregs ameliorate MOG-induced EAE through IL-2-triggered inhibition of effector T cells ENSG00000134982 ENSG00000197971 ENSG00000167074 ENSG00000237834 PMC10963452__F2 Schematic plots illustrate the signaling mechanism of various adipokines in intervertebral disc cells ENSG00000039537 ENSG00000174600 ENSG00000157500 ENSG00000168036 ENSG00000159346 ENSG00000172936 ENSG00000285070 ENSG00000096717 ENSG00000168610 PMC8305053__F1 Mutations in TSC Genes on Neurodevelopment and Synaptic Transmission ENSG00000169047 ENSG00000198793 ENSG00000164327 PMC5400646__F8 Quantitative proteomic analysis of gastric cancer tissue reveals novel proteins in platelet-derived growth factor B signaling pathway ENSG00000197956 ENSG00000126432 PMC4260148__F3 Details of genes in the ‘acute phase response’ biological pathway identified in Ingenuity Pathway Analysis, which are differentially expressed in the frontal section of SHRSP vs. WKY rats at 5 weeks of age ENSG00000180210 ENSG00000198793 ENSG00000171560 ENSG00000132693 PMC7541823__F7 Antigen presentation, T‐cell responses and activation of the cytosolic surveillance pathway (CSP) in the case of Mycobacterial infection of APCs ENSG00000164430 ENSG00000158481 ENSG00000158477 ENSG00000273686 PMC8539333__F1 Ochratoxin A-Induced Nephrotoxicity: Up-to-Date Evidence ENSG00000162711 ENSG00000135446 ENSG00000140505 ENSG00000123374 ENSG00000140465 ENSG00000168610 ENSG00000106546 PMC9039735__F3 Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns ENSG00000143799 ENSG00000105835 ENSG00000102699 ENSG00000123572 ENSG00000291803 ENSG00000278488 ENSG00000157064 ENSG00000173614 PMC8708448__F4 Nanoparticle-Based RNAi Therapeutics Targeting Cancer Stem Cells: Update and Prospective ENSG00000106571 ENSG00000166813 ENSG00000128602 PMC3844392__F1 Cross-talk between HIF and p53 as mediators of molecular responses to physiological and genotoxic stresses ENSG00000120868 ENSG00000078237 ENSG00000162772 PMC8708448__F3 Nanoparticle-Based RNAi Therapeutics Targeting Cancer Stem Cells: Update and Prospective ENSG00000168283 ENSG00000150457 ENSG00000131023 PMC7676498__F2 The Microenvironment in Controlling the Fate of Bioprinted Stem Cells ENSG00000019991 ENSG00000138798 ENSG00000198793 ENSG00000168036 PMC8708448__F2 Nanoparticle-Based RNAi Therapeutics Targeting Cancer Stem Cells: Update and Prospective ENSG00000112576 ENSG00000283780 ENSG00000198435 ENSG00000136997 ENSG00000124762 PMC8708448__F1 Nanoparticle-Based RNAi Therapeutics Targeting Cancer Stem Cells: Update and Prospective ENSG00000281324 ENSG00000137673 ENSG00000116729 ENSG00000162337 ENSG00000135100 ENSG00000026508 ENSG00000168036 ENSG00000154310 ENSG00000132170 PMC12171307__F3 Common regular pathways of ncRNAs ENSG00000135547 ENSG00000107562 ENSG00000281324 ENSG00000275385 ENSG00000198793 ENSG00000170558 ENSG00000124107 ENSG00000168036 ENSG00000168610 ENSG00000230034 ENSG00000170365 ENSG00000170961 ENSG00000052850 ENSG00000148498 ENSG00000117020 ENSG00000143320 ENSG00000102312 ENSG00000123374 ENSG00000154310 ENSG00000282899 PMC11910855__F8 Schematic diagram illustrates the impact of targeted activation of ErbB4 receptor on hippocampal neuronal damage, neuroinflammation, and cognitive functions in mice exposed to PS-MPs ENSG00000162711 ENSG00000136869 ENSG00000088538 ENSG00000142082 ENSG00000102003 ENSG00000178568 ENSG00000067715 PMC12171307__F1 EMT and Tumors ENSG00000012048 ENSG00000117020 ENSG00000291971 ENSG00000116132 ENSG00000112715 ENSG00000168610 ENSG00000146648 PMC3335376__F8 Therapeutic modulation of the TP53 pathway ENSG00000149311 ENSG00000175054 ENSG00000152409 ENSG00000172167 ENSG00000165392 ENSG00000124766 ENSG00000139372 ENSG00000197299 ENSG00000168040 ENSG00000168610 ENSG00000140464 PMC4227160__F4 Proposed model of the roles of CDKN1A and KIF20A in cell cycle control via RB/E2F pathway ENSG00000149311 ENSG00000175054 ENSG00000138778 ENSG00000135446 ENSG00000112984 ENSG00000123374 ENSG00000105810 ENSG00000124762 PMC3335376__F4 Illustration of p53 TIAs in lymphocytes ENSG00000132906 ENSG00000065833 ENSG00000002330 ENSG00000198793 ENSG00000164305 PMC4747358__F3 Personalized comprehensive molecular profiling of high risk osteosarcoma: Implications and limitations for precision medicine ENSG00000128310 ENSG00000274382 ENSG00000133105 ENSG00000163209 ENSG00000077585 ENSG00000136997 ENSG00000168412 ENSG00000168036 ENSG00000132478 ENSG00000198049 PMC9406846__F4 Clinical and Molecular Implications of Osteopontin in Heart Failure ENSG00000175054 ENSG00000198793 PMC8923702__F7 Mannan-Binding Lectin Regulates the Th17/Treg Axis Through JAK/STAT and TGFB/SMAD Signaling Against Candida albicans Infection ENSG00000105639 ENSG00000168610 PMC3737294__F1 Pancreatic cancers rely on a novel glutamine metabolism pathway to maintain redox balance ENSG00000125166 ENSG00000065833 ENSG00000122966 ENSG00000172005 PMC2714846__F6 Estradiol-17B, prostaglandin E2 (PGE2) and the prostaglandin E2 receptor are involved in PGE2 positive feedback loop in the porcine endometrium ENSG00000125384 ENSG00000073756 PMC11695279__F4 M6A-mediated tumor regulation in the immune microenvironment ENSG00000145388 ENSG00000149658 ENSG00000073792 ENSG00000136869 ENSG00000091542 ENSG00000168610 ENSG00000165819 ENSG00000141526 ENSG00000136231 PMC12179417__F6 Endoplasmic reticulum stress promotes the immunosuppressive activity of M2 macrophages and myeloid‐derived suppressor cells to enhance tumor immune escape ENSG00000128272 ENSG00000198053 ENSG00000118520 ENSG00000100219 ENSG00000168610 ENSG00000007171 PMC12179417__F5 Endoplasmic reticulum stress affects the function of dendritic cells and T cells, leading to immune evasion ENSG00000128272 ENSG00000197930 ENSG00000100219 PMC5989534__F10 Schematic summary showing how VPS35 might regulate LRRK2 and LRRK2 protein kinase activity and hence PD ENSG00000111237 ENSG00000069329 PMC9004553__F8 Construction and evaluation of a nomogram for predicting survival in patients with lung cancer ENSG00000123975 ENSG00000277909 ENSG00000077152 ENSG00000131747 ENSG00000101057 ENSG00000100526 ENSG00000167900 ENSG00000117399 ENSG00000072571 ENSG00000145604 ENSG00000111665 ENSG00000094804 ENSG00000156970 ENSG00000089685 ENSG00000171848 ENSG00000076382 ENSG00000071539 ENSG00000108106 PMC12179417__F4 Endoplasmic reticulum stress on antigen–MHC‐I complex and natural killer cells ENSG00000128272 ENSG00000100219 ENSG00000204520 PMC3656827__F2 Suppressive and pro-inflammatory roles for IL-4 in the pathogenesis of experimental drug-induced liver injury: a review ENSG00000105639 PMC4978167__F1 Integration of Endothelial Protease-activated Receptor-1 Inflammatory Signaling by Ubiquitin ENSG00000163914 PMC9611148__F3 STING in Non-Alcoholic Fatty Liver Diseases: Potential Therapeutic Targets in Inflammation-Carcinogenesis Pathway ENSG00000183735 ENSG00000164430 PMC3514733__F1 Chemotactic signaling pathway in sperm ENSG00000145321 PMC9611148__F2 STING in Non-Alcoholic Fatty Liver Diseases: Potential Therapeutic Targets in Inflammation-Carcinogenesis Pathway ENSG00000164430 ENSG00000144895 PMC6679869__F1 The role of inflammasomes in lupus nephritis ENSG00000163568 ENSG00000163565 ENSG00000136869 PMC2721475__F1 Downstream targets of IGF-1R ENSG00000169047 ENSG00000198793 PMC8622815__F1 AHR Ligands in Skin Homeostasis and Cutaneous Inflammation ENSG00000110711 ENSG00000291971 ENSG00000171759 ENSG00000106546 PMC7585866__F2 Pathogenesis of renin-angiotensin system in acute lung injury caused by viral infections ENSG00000130234 ENSG00000184012 PMC7585866__F1 Diagram of regulatory mechanism of renin-angiotensin system (RAS) ENSG00000130234 PMC10949864__F3 Mechanisms for the extracellular acidification inducing alterations of Ca2+ fluxes ENSG00000133107 ENSG00000144935 ENSG00000173786 ENSG00000177464 ENSG00000072315 ENSG00000196689 PMC9384336__F5 Comprehensive analysis of pathways in Coronavirus 2019 (COVID-19) using an unsupervised machine learning method ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC9437842__F4 GRPR neural and signalling pathways ENSG00000164128 ENSG00000078747 PMC10949864__F2 Cancer-associated alterations of Ca2+ fluxes at acidic tumor microenvironment and targets ENSG00000133107 ENSG00000144935 ENSG00000144895 ENSG00000118515 ENSG00000168036 ENSG00000067900 ENSG00000072315 ENSG00000184207 ENSG00000168610 ENSG00000196689 PMC4403492__F1 HPV carcinogenesis ENSG00000135446 ENSG00000164362 ENSG00000132510 ENSG00000139687 PMC5532627__F2 Linking processing of clustered DNA damage and immune response ENSG00000149311 ENSG00000108691 PMC4005972__F4 Proteins involved in the BCR signaling pathways ENSG00000100290 ENSG00000002330 ENSG00000010810 ENSG00000135446 ENSG00000198793 ENSG00000197943 ENSG00000076641 ENSG00000105810 PMC10378342__F2 Intravenous Immunoglobulin in Kawasaki Disease—Evolution and Pathogenic Mechanisms ENSG00000162711 ENSG00000150782 ENSG00000125538 ENSG00000082512 PMC3735686__F1 Nucleotide excision DNA repair pathway as a therapeutic target in patients with high-risk diffuse large B cell lymphoma ENSG00000012061 ENSG00000132646 ENSG00000177084 ENSG00000136936 PMC8907745__F2 Molecular Brakes of Adipose Tissue Lipolysis ENSG00000169047 ENSG00000177666 PMC8907745__F1 Molecular Brakes of Adipose Tissue Lipolysis ENSG00000166819 ENSG00000042832 ENSG00000135245 ENSG00000123689 ENSG00000132170 PMC7290982__F1 GD T cells activation ENSG00000134982 ENSG00000197429 ENSG00000231179 ENSG00000204520 PMC7968373__F1 Swimming towards solutions: using fish and frogs as models for understanding RASopathies ENSG00000110395 ENSG00000166068 ENSG00000108061 ENSG00000196712 PMC199174__F9 Models for the function of Ser307 phosphorylation ENSG00000125538 PMC2533145__F10 Rap1 and glycolytic/TCA cycle reaction ENSG00000074800 ENSG00000172955 PMC4592441__F4 Myc-regulated metabolic pathways in cancer ENSG00000131473 ENSG00000136997 ENSG00000115419 PMC10158029__F12 The regulator mechanism of S100A16 in Glioma ENSG00000188643 ENSG00000139842 ENSG00000131023 PMC11699442__F4 Dietary acrylamide on kidney and liver health: Molecular mechanisms and pharmacological implications ENSG00000198793 PMC11763285__F5 Regulatory pathways controlling cell proliferation and differentiation ENSG00000119723 ENSG00000186575 ENSG00000203485 ENSG00000070831 ENSG00000149269 ENSG00000198793 ENSG00000143622 PMC8324353__F6 Antitumor Effect of Lenvatinib Combined with Alisertib in Hepatocellular Carcinoma by Targeting the DNA Damage Pathway ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000101224 ENSG00000138385 ENSG00000139618 PMC6201924__F4 Proteomic analysis of Lactobacillus casei GCRL163 cell-free extracts reveals a SecB homolog and other biomarkers of prolonged heat stress ENSG00000197713 ENSG00000186063 PMC4190558__F1 Repair of oxidative DNA lesions by the MMR pathway ENSG00000105486 ENSG00000132781 ENSG00000132646 ENSG00000070950 ENSG00000095002 ENSG00000122512 PMC4629217__F2 Roles of FXR in regulating lipid and glucose metabolism ENSG00000166278 ENSG00000026103 PMC156758__F1 NEW EMBO MEMBER’S REVIEW ENSG00000113520 ENSG00000127191 PMC6909742__F2 NADPH Oxidases in the Etiology of Obesity and Metabolic Syndrome: Contribution of Individual Isoforms and Cell Biology ENSG00000137857 ENSG00000140279 ENSG00000086991 PMC7696043__F1 Nuclear factor-kappa light chain enhancer of activated B cells (NFKB) pathways ENSG00000104856 ENSG00000226275 ENSG00000173039 PMC5084660__F3 Putative molecular pathway that links GSK3B activity with the resistance of pancreatic cancer cells to DNA damage induced by gemcitabine and ionizing radiation ENSG00000135446 ENSG00000170430 ENSG00000168036 ENSG00000105810 PMC6909742__F5 NADPH Oxidases in the Etiology of Obesity and Metabolic Syndrome: Contribution of Individual Isoforms and Cell Biology ENSG00000196591 PMC5380843__F8 Proposed model for activation of IFN by doxorubicin bypassing IFN antagonism by Ebola virus VP35 protein ENSG00000149311 ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000131747 ENSG00000276561 PMC5078034__F8 Inulanolide A as a new dual inhibitor of NFAT1-MDM2 pathway for breast cancer therapy ENSG00000175054 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000171791 PMC9631451__F8 Quantification of promoting efficiency and reducing toxicity of Traditional Chinese Medicine: A case study of the combination of Tripterygium wilfordii hook. f. and Lysimachia christinae hance in the treatment of lung cancer ENSG00000132906 ENSG00000104365 ENSG00000185386 ENSG00000157764 ENSG00000177606 ENSG00000166501 ENSG00000269335 ENSG00000169032 ENSG00000112715 ENSG00000073756 ENSG00000164305 PMC6696055__F2 Regulation of autophagy by ROS ENSG00000149311 ENSG00000177169 ENSG00000126775 ENSG00000057663 PMC7459008__F1 PI3K-Akt pathway mediated antiviral mechanism in silkworm Antheraea mylitta ENSG00000107338 ENSG00000005882 ENSG00000169047 ENSG00000198793 ENSG00000118515 PMC7843495__F3 Mitochondria-related core genes and TF-miRNA-hub mrDEGs network in breast cancer ENSG00000079435 PMC7493965__F10 Empagliflozin reduces high glucose-induced oxidative stress and miR-21-dependent TRAF3IP2 induction and RECK suppression, and inhibits human renal proximal tubular epithelial cell migration and epithelial-tomesenchymal transition ENSG00000100234 ENSG00000087245 ENSG00000125538 ENSG00000056972 PMC6443597__F8 miR-4739/BMP-7/Smad1/5/9 pathway induces pleural fibrosis ENSG00000170365 ENSG00000120693 ENSG00000108821 PMC8121554__F6 Isoquercitrin protects HUVECs against high glucose-induced apoptosis through regulating p53 proteasomal degradation ENSG00000171791 PMC4292169__F1 The meiotic recombination pathway ENSG00000054796 PMC6218458__F1 Canonical Wnt pathway and the role of the LRP6 receptor ENSG00000281324 ENSG00000134982 ENSG00000168036 PMC5845557__F2 Invariant NKT (iNKT) cell activity within the tumor microenvironment (TME) ENSG00000158473 ENSG00000111537 ENSG00000134982 PMC1955758__F2 How both apoptotic death and immunity may be triggered by dsRNA ENSG00000002330 ENSG00000168040 ENSG00000135828 ENSG00000026103 PMC11828848__F4 Enzymes of energy metabolic pathways divergent in UGT2B17-deficient livers ENSG00000136731 ENSG00000049239 ENSG00000173599 PMC3555518__F1 Mechanism of miRNA expression and/or function perturbation ENSG00000108654 ENSG00000128191 ENSG00000113360 PMC3079374__F1 Simplified schematics of the MAPK and PI3K pathways in melanoma and the clinical compounds available for their inhibition ENSG00000157764 ENSG00000198793 ENSG00000164327 PMC6957369__F3 Core analysis of genes differentially regulated by SP-D nitrosylation ENSG00000134460 ENSG00000115008 ENSG00000081041 ENSG00000137673 ENSG00000007908 ENSG00000116717 ENSG00000166670 ENSG00000125347 ENSG00000073756 ENSG00000007171 ENSG00000102245 ENSG00000125538 ENSG00000172936 ENSG00000162692 ENSG00000115009 ENSG00000026103 PMC6781692__F1 Shh signaling pathway in hepatocellular carcinoma ENSG00000124216 ENSG00000106571 ENSG00000164690 ENSG00000171791 ENSG00000128602 ENSG00000131873 PMC6989408__F5 Mitochondria-associated ER membranes in normal versus cancer cells ENSG00000139921 ENSG00000116688 ENSG00000179364 ENSG00000171109 PMC3298638__F2 Screening for small molecule inhibitors of embryonic pathways: Sometimes you gotta crack a few eggs ENSG00000281324 ENSG00000162337 ENSG00000283780 ENSG00000168036 ENSG00000128602 PMC6627123__F5 Involvement of FGFR4-related signaling pathways ENSG00000107338 ENSG00000291971 ENSG00000167910 ENSG00000198793 PMC12217889__F4 Crosstalk Between the C1 Subpopulation and EndoCs, ECs, and Macrophages ENSG00000105894 ENSG00000107562 ENSG00000110492 ENSG00000144476 PMC3989895__F2 Simplified pathway map of CCN1 and CCN2-dependent outside-in signaling pathways regulating endothelial cell function and behavior ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000130881 ENSG00000134569 ENSG00000291971 ENSG00000118816 ENSG00000146648 ENSG00000065802 PMC4850435__F6 Evolutionary redesign of the Atlantic cod (Gadus morhua L.) Toll-like receptor repertoire by gene losses and expansions ENSG00000174125 ENSG00000169248 ENSG00000154589 ENSG00000168040 ENSG00000150455 ENSG00000277943 ENSG00000169245 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000138755 ENSG00000125538 ENSG00000136869 ENSG00000172936 ENSG00000064012 ENSG00000164342 PMC6117946__F3 Non-enzymatic Krebs cycle-like reactions that occur in the presence of peroxydisulfate and FeS form a network that closely mimics the typical (oxidative) Krebs cycle and the glyoxylate shunt ENSG00000182511 ENSG00000122966 ENSG00000172005 PMC8438071__F8 In situ delivery of biobutyrate by probiotic Escherichia coli for cancer therapy ENSG00000143799 ENSG00000143839 PMC6006503__F1 Role and molecular pathway of IL-32 in cancer ENSG00000125538 ENSG00000168036 ENSG00000168610 PMC12172856__F7 Interaction network of key signaling pathway-mRNA-miRNA ENSG00000169554 ENSG00000124216 ENSG00000070831 ENSG00000169047 ENSG00000095015 ENSG00000134363 ENSG00000281877 ENSG00000114739 ENSG00000130513 PMC7169114__F2 Long noncoding RNAs (lncRNAs) regulate innate immune responses through activation of RIG‐I and via deregulation of epigenetic mechanisms ENSG00000173039 ENSG00000136869 PMC8004488__F8 Astrocytes morpho-functional alterations in ADLD phenotype ENSG00000141086 ENSG00000128342 ENSG00000168610 PMC6349383__F3 Summary of the oncogenic pathways genetically disrupted in the UM-SCC oral cavity cell line panel ENSG00000116044 ENSG00000148400 ENSG00000168036 ENSG00000111321 ENSG00000079999 ENSG00000083857 ENSG00000136997 ENSG00000105810 ENSG00000077782 ENSG00000064012 ENSG00000139687 ENSG00000146648 ENSG00000140443 PMC8125319__F2 Senescent Cells in Acquired Drug Resistance and Secondary Cancer in BRAFi-Treated Melanoma ENSG00000157764 ENSG00000198793 PMC64750__F4 Metabolic pathways related to cell-wall formation ENSG00000084774 PMC4033425__F3 Cell-cell coupling in the somitogenesis clock ENSG00000111537 ENSG00000090402 ENSG00000106003 PMC2718282__F8 The role of Mal connecting PI3K to TLR2/6 ENSG00000174125 ENSG00000172005 ENSG00000172936 PMC3069496__F1 miRNA biogenesis pathway ENSG00000092847 ENSG00000128191 ENSG00000113360 ENSG00000134698 ENSG00000123908 PMC6619735__F9 Proposed model illustrating the mechanism of arctigenin-mediated AB production inhibition and AB clearance promotion ENSG00000177169 ENSG00000142192 ENSG00000144895 ENSG00000198793 PMC3395995__F1 Alloantigen presentation via the direct, semi-direct and indirect pathways following organ transplantation, and (B) the relative intensity of each antigen-presentation pathway during the post-transplantation (post-Tx) period ENSG00000134982 ENSG00000162924 PMC9586542__F6 Lipid pathway dysfunction is prevalent in patients with Parkinson’s disease ENSG00000042832 ENSG00000173599 PMC3067333__F5 Schematic presentation of Nag PTS and parts of the central metabolism of R ENSG00000261701 ENSG00000150787 ENSG00000131828 PMC5682418__F5 Selected miRNA-mRNA interaction networks involved in Jak-STAT signaling pathway ENSG00000110711 ENSG00000213928 ENSG00000122756 ENSG00000198793 ENSG00000137193 ENSG00000171791 ENSG00000168610 PMC7093977__F3 Phenotypic response of microglia on dietary fatty acid exposure ENSG00000136535 ENSG00000172936 ENSG00000136869 PMC5682418__F4 Selected miRNA-mRNA interaction networks involved in T cell receptor signaling pathway ENSG00000291603 ENSG00000111537 ENSG00000110395 ENSG00000213658 ENSG00000010810 ENSG00000135446 ENSG00000163599 ENSG00000113263 ENSG00000130669 PMC7962119__F3 Cellular senescence (i.e., permanent cessation of cell division) is triggered by a variety of stresses ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000171791 ENSG00000184481 PMC7037145__F3 Conflicting role of JNKs in dermal fibroblast biology ENSG00000108821 PMC7697568__F1 Wnt signaling pathway ENSG00000134982 ENSG00000108375 ENSG00000185269 PMC7388440__F6 RA pathway model ENSG00000185483 ENSG00000168036 PMC5702396__F1 Apoptotic Pathways in Glioblastoma PMC8450475__F1 Manifestations and Management of Hepatic Dysfunction in Congenital Disorders of Glycosylation ENSG00000134851 ENSG00000086848 ENSG00000120697 ENSG00000182220 ENSG00000214160 ENSG00000136710 ENSG00000244045 ENSG00000182858 PMC10933834__F9 Biosynthesis pathway and gene cluster of erythromycin ENSG00000175198 ENSG00000134575 ENSG00000014257 PMC8012461__F2 Biomaterials Regulate Mechanosensors YAP/TAZ in Stem Cell Growth and Differentiation ENSG00000166167 ENSG00000126016 ENSG00000186575 ENSG00000078900 ENSG00000109321 ENSG00000044115 ENSG00000163914 ENSG00000136997 ENSG00000150457 ENSG00000131023 ENSG00000089225 ENSG00000178568 PMC7697568__F3 Target therapies for ligand-dependent tumors ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000108375 PMC1584297__F9 Cross-talk between the NFKB and the STAT3 pathways ENSG00000168610 PMC10917541__F3 NMN-mediated longevity and the main reasons for decreasing NAD+ level with age ENSG00000096717 ENSG00000173273 PMC5833861__F2 Cell death-based treatments of melanoma:conventional treatments and new therapeutic strategies ENSG00000134982 PMC5468379__F1 Viral RNA detection by RLRs and TLRs, signaling pathways and overview of FMDV strategies aimed at its supression ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000164342 ENSG00000142166 PMC9697406__F1 Emerging Role of Chromatin Remodeling Complexes in Ovarian Cancer ENSG00000094631 ENSG00000117713 ENSG00000175054 ENSG00000118007 ENSG00000151012 ENSG00000198793 ENSG00000196591 ENSG00000164362 ENSG00000176105 ENSG00000095002 ENSG00000100100 PMC4428707__F11 SP-R210 (Myo18A) Isoforms as Intrinsic Modulators of Macrophage Priming and Activation ENSG00000170458 ENSG00000136869 PMC7802216__F5 Roles of palmitoylation during structural LTP ENSG00000100151 ENSG00000106683 ENSG00000070831 ENSG00000170558 PMC8273837__F4 Upregulation of receptor tyrosine kinase-like orphan receptor 2 in idiopathic pulmonary fibrosis ENSG00000163904 ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000175592 ENSG00000168036 ENSG00000118971 PMC3055758__F8 Mechanism of cAMP inhibition of MAPK activity ENSG00000291971 ENSG00000146469 ENSG00000138798 PMC5672329__F3 Outside-in signaling through class I PI3Ks ENSG00000291971 ENSG00000280477 ENSG00000135605 ENSG00000010671 PMC8636777__F4 Weighted Gene Co-Expression Network Analysis and Treatment Strategies of Tumor Recurrence-Associated Hub Genes in Lung Adenocarcinoma ENSG00000166349 ENSG00000112276 ENSG00000171992 ENSG00000070831 ENSG00000285109 ENSG00000150672 ENSG00000163914 ENSG00000162924 ENSG00000166278 ENSG00000001626 ENSG00000150051 ENSG00000072415 PMC9412801__F2 Clinical Utility of the Sivelestat for the Treatment of ALI/ARDS: Moving on in the Controversy? ENSG00000174125 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC6274719__F1 Three apoptotic pathways (Extrinsic, intrinsic and granzyme pathways) ENSG00000145649 ENSG00000168040 PMC7175142__F4 Influence of lipid mediators on ER stress-dependent pathway.Disorders in synthesis or action of exogenous factors, like lipid mediators (black) may lead to the generation and accumulation of abnormal proteins (AP) ENSG00000100219 ENSG00000171791 PMC6415584__F1 Pyruvate and glutamate are 2 major metabolic hubs in GSCs ENSG00000173599 ENSG00000115419 ENSG00000159399 ENSG00000026103 PMC3895844__F3 Dopamine-DARPP32 feedback in cAMP signalling is a significant canonical pathway in an olanzapine-treated hippocampus ENSG00000171540 ENSG00000095794 PMC7175142__F3 Influence of lipid mediators on the mitochondrial pathway PMC3895844__F2 Ephrin receptor signalling is the most significant canonical pathway in an olanzapine-treated cerebellum ENSG00000160145 ENSG00000010810 ENSG00000138798 ENSG00000168610 ENSG00000089159 PMC7753989__F6 Schematic model depicting the role of ADAM17/HB‐EGF/EGFR signalling pathway in directional collective migration of epidermal cells ENSG00000113070 ENSG00000146648 PMC7175142__F1 Main apoptotic pathways ENSG00000102871 ENSG00000100219 ENSG00000171791 ENSG00000168040 PMC4483595__F4 Proposed mechanism to explain the protective effect of CFHR1,3 deletion on the development of IgAN ENSG00000116785 ENSG00000244414 PMC4483595__F1 Three pathways of complement activation ENSG00000039537 ENSG00000113600 ENSG00000291559 ENSG00000203710 ENSG00000244731 ENSG00000166278 PMC9033378__F7 Psoriasis Vulgaris of Blood Heat Syndrome in Plasma Based on Widely Targeted Techniques ENSG00000100473 ENSG00000173599 ENSG00000178922 PMC9033378__F6 Psoriasis Vulgaris of Blood Heat Syndrome in Plasma Based on Widely Targeted Techniques ENSG00000168003 ENSG00000115107 PMC8799876__F2 Targeting PI3K/AKT signaling for treatment of idiopathic pulmonary fibrosis ENSG00000128052 ENSG00000122194 PMC6247912__F2 Somatic mutations of the canonical signal transduction and tumor suppressor pathways in HCC ENSG00000116254 ENSG00000186532 ENSG00000108799 ENSG00000198793 ENSG00000181555 ENSG00000077463 ENSG00000107077 ENSG00000166164 ENSG00000183765 ENSG00000117713 ENSG00000012048 ENSG00000134899 ENSG00000144554 ENSG00000113318 ENSG00000177084 ENSG00000140464 ENSG00000196712 ENSG00000128908 ENSG00000118058 ENSG00000106682 ENSG00000005339 ENSG00000157764 ENSG00000173575 ENSG00000181544 ENSG00000103510 ENSG00000173674 ENSG00000163104 ENSG00000100888 ENSG00000126012 ENSG00000149311 ENSG00000138336 ENSG00000108604 ENSG00000165409 ENSG00000177200 ENSG00000055609 ENSG00000080603 ENSG00000149554 ENSG00000095002 ENSG00000146648 ENSG00000139718 ENSG00000198586 ENSG00000122512 ENSG00000016391 ENSG00000111642 ENSG00000197724 PMC12027943__F5 Compound–target–pathway interaction network ENSG00000143799 ENSG00000137561 ENSG00000228716 ENSG00000262406 ENSG00000291971 ENSG00000198793 ENSG00000113161 ENSG00000087586 ENSG00000101266 ENSG00000166851 ENSG00000122194 ENSG00000179295 ENSG00000183765 ENSG00000163631 ENSG00000126218 ENSG00000163558 ENSG00000077782 ENSG00000149554 ENSG00000146648 ENSG00000113448 ENSG00000127948 ENSG00000140443 PMC7680500__F6 Quantitative proteomics revealed energy metabolism pathway alterations in human epithelial ovarian carcinoma and their regulation by the antiparasite drug ivermectin: data interpretation in the context of 3P medicine ENSG00000135776 ENSG00000166278 ENSG00000146648 PMC8066409__F2 Non-transcriptional activation of IRF3 by RIPA causes cell death ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC3475405__F3 Blood–brain barrier (BBB) transport in homeostasis of brain AB ENSG00000125538 PMC2949529__F2 O-GlcNAc Signaling: A Metabolic Link Between Diabetes and Cancer? ENSG00000147162 ENSG00000169047 PMC8066409__F1 Transcriptional and non-transcriptional activation of IRF3 by virus-activated signaling pathways lead to host antiviral response ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000144895 ENSG00000291971 ENSG00000168036 ENSG00000131323 ENSG00000127191 ENSG00000146648 ENSG00000164342 PMC7426728__F2 DNA methylation regulates the PI3K/PTEN/AKT/mTOR signaling pathway in the resistance to therapy in cancer ENSG00000002330 ENSG00000088305 ENSG00000198793 ENSG00000155792 PMC7426728__F1 Activation of the Wnt/Beta-catenin signaling pathway in the resistance to therapy in cancer by methylation ENSG00000156076 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000050165 ENSG00000168036 ENSG00000104332 PMC7680500__F3 Quantitative proteomics revealed energy metabolism pathway alterations in human epithelial ovarian carcinoma and their regulation by the antiparasite drug ivermectin: data interpretation in the context of 3P medicine ENSG00000197444 ENSG00000172340 ENSG00000146701 ENSG00000101365 ENSG00000062485 PMC9675292__F1 Insulin Receptor Substrate Signaling Controls Cardiac Energy Metabolism and Heart Failure ENSG00000180210 ENSG00000173599 ENSG00000169710 PMC7680500__F2 Quantitative proteomics revealed energy metabolism pathway alterations in human epithelial ovarian carcinoma and their regulation by the antiparasite drug ivermectin: data interpretation in the context of 3P medicine ENSG00000074800 ENSG00000067057 PMC5904231__F2 Process diagram indicating the p16INK4a/p14ARF–RB–p53 pathway in normal conditions ENSG00000149311 ENSG00000175054 ENSG00000116254 PMC6626430__F6 Proposed model illustrating the anti-IL-1B activity of matrine ENSG00000168872 ENSG00000162711 ENSG00000125538 ENSG00000174953 ENSG00000172936 ENSG00000136869 PMC9466978__F1 Decoding the Role of Familial Parkinson’s Disease-Related Genes in DNA Damage and Repair ENSG00000012048 ENSG00000158828 ENSG00000138385 PMC5216946__F13 Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer ENSG00000163914 ENSG00000197429 ENSG00000113161 ENSG00000185591 PMC3612034__F3 Identifying Resistance Mechanisms against Five Tyrosine Kinase Inhibitors Targeting the ERBB/RAS Pathway in 45 Cancer Cell Lines ENSG00000119888 ENSG00000010278 ENSG00000116977 PMC6627955__F4 Sphingolipids (SLs) together with the responsible key genes involved in regulating the pathway ENSG00000100422 ENSG00000262785 ENSG00000134824 ENSG00000149485 ENSG00000169710 ENSG00000099194 ENSG00000148154 ENSG00000124253 ENSG00000026103 PMC9218363__AF1 Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A ENSG00000198793 ENSG00000168040 PMC10374032__F1 Genome-scale metabolic modeling and in silico analysis of opportunistic skin pathogen Cutibacterium acnes ENSG00000181924 ENSG00000065833 ENSG00000197713 ENSG00000165996 ENSG00000122966 ENSG00000196549 ENSG00000172005 ENSG00000256269 ENSG00000062485 PMC4612707__F5 Quantitative analysis of transcriptional levels of genes in the xylose metabolic pathway and the central carbon metabolism pathway ENSG00000074800 ENSG00000172005 ENSG00000124253 PMC7082774__F1 Emerging roles for branched chain amino acid metabolism in cancer ENSG00000131473 ENSG00000198793 ENSG00000163644 PMC8137995__F4 Modeling the Th17 and Tregs Paradigm: Implications for Cancer Immunotherapy ENSG00000162594 ENSG00000198793 ENSG00000113263 ENSG00000049768 ENSG00000149806 PMC8160296__F5 Circular RNAs in Hepatocellular Carcinoma: Emerging Functions to Clinical Significances ENSG00000002330 PMC9343399__F7 Key role of aminoacylase-1 in myocardial fibrosis and the regulatory effect of 20(S)-ginsenoside Rg3 in heart failure PMC12231332__F3 Relationships between pro-inflammatory cytokines and bone signaling pathways affecting osteoblastogenesis and osteoclastogenesis ENSG00000167941 ENSG00000125538 ENSG00000168036 ENSG00000100985 ENSG00000175104 ENSG00000132693 ENSG00000131196 PMC8592284__F4 Functional Amino Acids and Autophagy: Diverse Signal Transduction and Application ENSG00000131473 ENSG00000128272 ENSG00000285250 ENSG00000103257 ENSG00000115419 PMC7527140__F2 Deduced sterol biosynthesis pathways in Symbiodiniaceae ENSG00000172893 ENSG00000197429 PMC4012865__F9 Activation of DCs by HKBA showing the stimulation of TLR2 and TLR9 and cross-talk between their respective signal transduction pathways ENSG00000239732 ENSG00000172936 PMC4388554__F11 Role of Notch Signalling in CD34+ Chronic Myeloid Leukaemia Cells: Cross-Talk between Notch and BCR-ABL ENSG00000186716 ENSG00000198793 ENSG00000168036 ENSG00000114315 PMC4262066__F3 Schematic presentation of mechanisms leading to cell cycle deregulation in growth plate dtd chondrocytes ENSG00000135446 ENSG00000168036 ENSG00000105810 PMC8468939__F8 Mechanistic Insights of Anti-Immune Evasion by Nobiletin through Regulating miR-197/STAT3/PD-L1 Signaling in Non-Small Cell Lung Cancer (NSCLC) Cells ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC7001001__F4 Bioinformatics Analysis of miR-124-3p and Its Downstream Targeted Genes(A) The genetic interaction network of miR-124-3p built by Biovista Vizit ENSG00000198964 ENSG00000140564 ENSG00000196975 ENSG00000163251 ENSG00000198561 ENSG00000102081 ENSG00000173039 ENSG00000150093 ENSG00000067900 ENSG00000198626 ENSG00000160691 PMC5582996__F1 Configuring a robust nervous system with Fat cadherins ENSG00000166341 ENSG00000142192 ENSG00000165323 PMC3693462__F1 BRCA1: A Missing Link in the Fanconi Anemia/BRCA Pathway ENSG00000012048 ENSG00000083093 ENSG00000108384 ENSG00000162607 ENSG00000139618 PMC7847682__F1 External and intrinsic mechanisms to mediate immunotherapy resistance for CSCs in HCC ENSG00000134982 ENSG00000168036 ENSG00000115009 PMC6618483__F8 Model describing Etv4 and Etv5 induction following distal NGF stimulation ENSG00000244405 ENSG00000175832 PMC3591264__F7 Dissection of Regulatory Networks that Are Altered in Disease via Differential Co-expression ENSG00000168028 ENSG00000291931 ENSG00000166441 ENSG00000198918 ENSG00000124614 ENSG00000162244 ENSG00000213741 ENSG00000101361 ENSG00000138326 ENSG00000145592 ENSG00000136942 ENSG00000083845 ENSG00000172809 ENSG00000071082 ENSG00000241343 ENSG00000197958 PMC4409526__F4 Diagram depicting molecules involved in actin cytoskeletal regulation mediated by NMDA signaling pathways and having altered mRNA expression in bipolar disorder ENSG00000070087 ENSG00000160145 ENSG00000102606 ENSG00000070831 ENSG00000143776 ENSG00000077522 ENSG00000079482 ENSG00000108819 ENSG00000113758 ENSG00000067900 ENSG00000186298 PMC3591264__F6 Dissection of Regulatory Networks that Are Altered in Disease via Differential Co-expression PMC4409526__F3 Diagram depicting altered mRNA expression of molecules involved in the regulation of the actin cytoskeleton by NMDA signaling pathways in schizophrenia ENSG00000148498 ENSG00000106683 ENSG00000160145 ENSG00000070831 ENSG00000077522 ENSG00000079482 ENSG00000108819 ENSG00000113758 ENSG00000067900 ENSG00000186298 PMC7392137__F1 The original model for Wg signaling in Drosophila, the core of the current model for the canonical Wnt signal transduction (the Wnt/Beta-Catenin pathway) ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000105656 ENSG00000168036 PMC7392137__F2 Two well-known non-canonical Wnt signalling pathways, including Wnt/Ca2+ (right) and Wnt/PCP (left) ENSG00000169071 ENSG00000100592 ENSG00000177606 ENSG00000185483 PMC3386597__F4 AhR-related signaling molecules are enriched within the AML Signalisome ENSG00000145632 ENSG00000087245 ENSG00000173894 ENSG00000178573 ENSG00000088305 ENSG00000138185 ENSG00000105810 ENSG00000114166 ENSG00000134686 ENSG00000106546 ENSG00000069667 PMC3386597__F3 AML Signalisome ENSG00000280831 ENSG00000157657 ENSG00000110315 ENSG00000181274 ENSG00000109113 ENSG00000118729 ENSG00000134759 ENSG00000106546 ENSG00000291944 ENSG00000069667 ENSG00000006194 ENSG00000173894 ENSG00000178573 ENSG00000125686 ENSG00000197386 ENSG00000174197 ENSG00000087842 ENSG00000112182 ENSG00000177600 ENSG00000149806 ENSG00000168807 ENSG00000087245 ENSG00000092439 ENSG00000115163 ENSG00000099985 ENSG00000119919 ENSG00000099864 ENSG00000198363 ENSG00000159921 ENSG00000122566 ENSG00000157800 ENSG00000158270 ENSG00000142149 ENSG00000152377 ENSG00000213347 ENSG00000162599 ENSG00000114166 ENSG00000134686 PMC3819341__F1 Summary of therapeutic invention points in the myostatin signaling pathway ENSG00000198793 ENSG00000070404 PMC5808457__F1 Tumor Suppressor Candidate 2 (TUSC2; FUS-1) and Human Cancers ENSG00000114383 ENSG00000146648 PMC4905210__F1 Targeting the mevalonate pathway using statins and its feedback loop using dipyridamole induces tumor cell apoptosis ENSG00000112972 ENSG00000130164 ENSG00000113161 PMC4428041__F3 Stem cell and progenitor fate in the mammalian intestine: Notch and lateral inhibition in homeostasis and disease ENSG00000152484 ENSG00000078747 ENSG00000048028 ENSG00000172238 PMC2639036__F1 Single-strand break repair pathways ENSG00000132646 ENSG00000039650 ENSG00000127948 ENSG00000138385 PMC4168797__F7 Paraquat hijacks the PPP to induce oxidative stress and cell death ENSG00000105953 ENSG00000115419 PMC4515436__F12 Short range signalling between germline stem cell and its niche ENSG00000133937 ENSG00000184371 PMC6874879__F2 LKB1 loss alters cancer cell biology ENSG00000177169 ENSG00000168958 ENSG00000198793 ENSG00000171109 ENSG00000079999 ENSG00000026103 PMC6874879__F1 LKB1-proficient tumors display coordinated control of metabolism, DNA repair, and mitochondrial dynamics ENSG00000168958 ENSG00000266173 ENSG00000198793 PMC7177879__F2 Regulatory network controlling SE induction in which the auxin-related epigenetic processes play a central role ENSG00000047410 ENSG00000134287 ENSG00000165527 PMC5835590__F9 Summary of the main differences between NE high and low subtypes of SCLC ENSG00000084093 ENSG00000183734 ENSG00000136997 ENSG00000136352 ENSG00000090932 ENSG00000139352 PMC8614792__F4 MicroRNA Sequencing Analysis in Obstructive Sleep Apnea and Depression: Anti-Oxidant and MAOA-Inhibiting Effects of miR-15b-5p and miR-92b-3p through Targeting PTGS1-NFKB-SP1 Signaling ENSG00000149311 ENSG00000175054 ENSG00000109220 ENSG00000285109 ENSG00000135446 ENSG00000123374 PMC10223772__F5 Proteins related to resistance in HIGS lines infected with A. flavus ENSG00000105722 ENSG00000188452 PMC5367635__F1 Metabolic reprogramming in T cell fate and function ENSG00000042832 ENSG00000198793 ENSG00000168685 ENSG00000026103 PMC7488620__F7 Parental RHC reverses ischemia-induced changes in rod phototransduction pathway proteins ENSG00000120500 ENSG00000078369 ENSG00000061918 ENSG00000109047 ENSG00000167083 ENSG00000128617 ENSG00000198515 ENSG00000132518 ENSG00000112599 ENSG00000114349 ENSG00000101890 ENSG00000095464 ENSG00000163914 ENSG00000281857 ENSG00000069966 PMC10390225__F2 Mononuclear phagocyte system in IgA nephropathy: pathogenesis and prognosis ENSG00000170458 PMC7373735__F1 General mechanism of ferroptosis associated with lipid, amino acid, and iron metabolism ENSG00000196839 ENSG00000167468 ENSG00000111684 ENSG00000115107 PMC8662361__F6 Aging Affects KV7 Channels and Perivascular Adipose Tissue-Mediated Vascular Tone ENSG00000214456 ENSG00000143252 ENSG00000150991 ENSG00000100412 ENSG00000134824 ENSG00000117118 ENSG00000169710 ENSG00000163541 ENSG00000105647 ENSG00000146701 ENSG00000062485 PMC4987476__F8 Graphical summary of anti-inflammatory activity of bee venom in LPS-activated BV2 glial cells ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC8395232__F1 Mitochondria-Induced Immune Response as a Trigger for Neurodegeneration: A Pathogen from Within ENSG00000183735 ENSG00000213928 ENSG00000239732 ENSG00000164430 ENSG00000163568 PMC3468610__F4 Genome-Wide Characterization of Pancreatic Adenocarcinoma Patients Using Next Generation Sequencing ENSG00000140992 ENSG00000019991 ENSG00000100906 ENSG00000109758 ENSG00000173039 ENSG00000162924 ENSG00000213341 ENSG00000168040 ENSG00000122194 ENSG00000164305 ENSG00000104368 ENSG00000132170 ENSG00000066468 ENSG00000117020 ENSG00000017797 ENSG00000078900 ENSG00000156299 ENSG00000177606 ENSG00000136997 ENSG00000006451 ENSG00000173535 ENSG00000171608 ENSG00000133027 PMC8220211__F6 JAK/STAT-Dependent Chimeric Antigen Receptor (CAR) Expression: A Design Benefiting From a Dual AND/OR Gate Aiming to Increase Specificity, Reduce Tumor Escape and Affect Tumor Microenvironment ENSG00000138378 PMC3262999__F1 Interaction between Jak2/Stat5 signaling and the PI3K/Akt1 pathway in mammary epithelial cells ENSG00000291971 ENSG00000113494 PMC8220211__F3 JAK/STAT-Dependent Chimeric Antigen Receptor (CAR) Expression: A Design Benefiting From a Dual AND/OR Gate Aiming to Increase Specificity, Reduce Tumor Escape and Affect Tumor Microenvironment ENSG00000138378 PMC7393602__F1 Nav1.5 promotes the activity of NHE-1, resulting in the acidification of the peri-membrane, which favors the proteolytic activity of Cat and MMPs (yellow line) ENSG00000124216 ENSG00000026508 PMC6721482__F2 The regulation of Keratin 6, 16 and 17 during skin wounding and in psoriasis ENSG00000111537 ENSG00000115415 ENSG00000198793 ENSG00000168610 ENSG00000146648 ENSG00000164342 PMC2878914__F1 Cross-regulation of signaling pathways: an example of nuclear hormone receptors and the canonical Wnt pathway ENSG00000168036 PMC3340364__F6 Genome-Wide Profiling Identified a Set of miRNAs that Are Differentially Expressed in Glioblastoma Stem Cells and Normal Neural Stem Cells ENSG00000132906 ENSG00000175054 ENSG00000164305 PMC6704427__F1 Genetic abnormalities in HNSCC contribute to poor tumor immunogenicity ENSG00000198793 ENSG00000121879 PMC5661397__F6 Pentose phosphate pathway (dotted lines) and associated metabolic pathways (solid lines) ENSG00000140263 PMC5866017__F6 Enriched pathways in cholangiocarcinoma ENSG00000143799 ENSG00000132906 ENSG00000030582 ENSG00000101146 ENSG00000039650 ENSG00000111530 ENSG00000112118 ENSG00000073111 ENSG00000127191 ENSG00000166508 ENSG00000105894 ENSG00000169245 ENSG00000069869 ENSG00000112242 ENSG00000076928 ENSG00000010810 ENSG00000088247 ENSG00000162521 ENSG00000253729 ENSG00000127948 PMC7141137__F3 Intracellular regulators that link morphogen signaling pathways during DV and AP patterning of the ectoderm in vertebrate embryos ENSG00000171956 ENSG00000138083 ENSG00000168036 PMC8601834__F2 Mitochondrial Mechanisms of Apoptosis and Necroptosis in Liver Diseases ENSG00000102871 ENSG00000120868 ENSG00000168040 ENSG00000285379 ENSG00000026103 PMC2713381__F8 MMP-9 controls Schwann cell proliferation and phenotypic remodeling via IGF-1 and ErbB receptor-mediated activation of MEK/ERK pathway ENSG00000005882 PMC6831629__F8 Hypothetical model to depict the role of Trpc1 channels in linking the inhibition of BMP pathway by noggin, and the activation of Cav1.2 channels in ectodermal cells ENSG00000144935 ENSG00000156925 PMC6597298__F7 Schematic diagram showing the critical role of FDPS in normal prostate and prostate cancer and its associated potential mecahnism (s) ENSG00000160752 ENSG00000115415 PMC7330943__F8 Estrogen signalling pathway (a) is solid active instead, prolactin pathway (b) results are not in the group of the strongest expression level ENSG00000120833 ENSG00000087245 ENSG00000186847 ENSG00000126803 ENSG00000115904 ENSG00000173908 ENSG00000262164 ENSG00000213341 ENSG00000100485 ENSG00000171446 ENSG00000113494 PMC5519011__F3 redGEM: Systematic reduction and analysis of genome-scale metabolic reconstructions for development of consistent core metabolic models ENSG00000144063 ENSG00000065833 ENSG00000122966 ENSG00000172005 ENSG00000082212 ENSG00000062485 PMC4408933__F3 Adipocytokine signaling pathway as represented in the Kyoto Encyclopedia of Genes and Genomes (KEGG; http://www.genome.jp/kegg/kegg1.html) (; , ) ENSG00000102871 ENSG00000198793 ENSG00000127191 ENSG00000168610 PMC2564730__F3 Use of MIMO models to infer regulatory interactions in breast cancer cells ENSG00000138798 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC9006445__F3 Targeting regulated cell death (RCD) with small-molecule compounds in triple-negative breast cancer: a revisited perspective from molecular mechanisms to targeted therapies ENSG00000168003 ENSG00000175054 ENSG00000151012 ENSG00000137275 ENSG00000129596 ENSG00000102871 ENSG00000167468 ENSG00000198793 ENSG00000123374 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC9006445__F2 Targeting regulated cell death (RCD) with small-molecule compounds in triple-negative breast cancer: a revisited perspective from molecular mechanisms to targeted therapies ENSG00000177169 ENSG00000110497 ENSG00000123395 ENSG00000126775 PMC8632930__F1 Antitumor effect of PARP inhibitors ENSG00000149311 ENSG00000012048 ENSG00000083093 ENSG00000173575 ENSG00000051180 ENSG00000138385 ENSG00000139618 PMC6995234__F7 Expression of genes in central metabolic pathway in wild-type (WT) and engineered M ENSG00000130957 ENSG00000197713 ENSG00000105953 ENSG00000167900 PMC9006445__F1 Targeting regulated cell death (RCD) with small-molecule compounds in triple-negative breast cancer: a revisited perspective from molecular mechanisms to targeted therapies ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000168610 ENSG00000026103 PMC4211430__F7 Indian Hedgehog Mediates Gastrin-Induced Proliferation in Stomach of Adult Mice ENSG00000110148 ENSG00000128602 ENSG00000163501 PMC4959089__F1 General schematic model of a NR signaling pathway ENSG00000173599 ENSG00000145321 PMC6948370__F11 Diagramatic representation of the possible molecular mechanism of CXXC4-mediated tamoxifen resistance ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000135446 ENSG00000168036 ENSG00000105810 ENSG00000168772 PMC9258696__F1 Osteoimmunology: The correlation between osteoclasts and the Th17/Treg balance in osteoporosis ENSG00000100985 ENSG00000131196 ENSG00000143387 PMC8523237__F1 Kidney Cell Pyroptosis in Chronic Kidney Disease and the Effects of Traditional Chinese Medicine ENSG00000162711 ENSG00000163568 ENSG00000091592 ENSG00000198947 PMC10305000__F6 Reconstructed fatty acid synthesis pathway of ST7-B ENSG00000091140 PMC8787129__F11 Liver Fibrosis—From Mechanisms of Injury to Modulation of Disease ENSG00000163914 PMC4954849__F1 Interplay between VEGF and Notch signaling is important for tip and stalk cell differentiation in physiological angiogenesis ENSG00000128917 ENSG00000168036 PMC8946298__F3 Cross-Talk between p53 and Wnt Signaling in Cancer ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC3646015__F6 Developmental Gene Discovery in a Hemimetabolous Insect: De Novo Assembly and Annotation of a Transcriptome for the Cricket Gryllus bimaculatus ENSG00000128602 PMC9006445__F4 Targeting regulated cell death (RCD) with small-molecule compounds in triple-negative breast cancer: a revisited perspective from molecular mechanisms to targeted therapies ENSG00000278718 ENSG00000162711 ENSG00000065675 ENSG00000102871 ENSG00000291971 ENSG00000126353 ENSG00000168040 ENSG00000168610 ENSG00000146648 PMC5533789__F6 Hypothetical signalling network and status in bovine cumulus cells modified by FSH-priming based on RNA-seq expression signature ENSG00000170961 ENSG00000105329 ENSG00000163661 ENSG00000276561 ENSG00000123610 PMC7869011__F4 Retinoic acid (RA) synthesis and signaling activation during in vitro cardiac differentiation ENSG00000121207 ENSG00000138207 ENSG00000121039 ENSG00000114115 PMC11545013__F10 Elevated RBP4 in Subclinical Ketosis Cows Inhibits Follicular Granulosa Cell Proliferation and Steroid Hormone Synthesis ENSG00000111012 ENSG00000138207 ENSG00000175305 PMC6593264__F2 Dual aspects of GM-CSF immunomodulatory effects ENSG00000168329 PMC7053436__F5 Central role for Ras-MAPK signaling in habituation learning ENSG00000104884 ENSG00000147044 ENSG00000169554 ENSG00000157764 ENSG00000106367 ENSG00000143442 ENSG00000104889 ENSG00000006283 ENSG00000095787 ENSG00000101680 ENSG00000004848 ENSG00000179915 ENSG00000109323 ENSG00000179295 ENSG00000006695 ENSG00000181090 ENSG00000156110 ENSG00000175115 ENSG00000048342 ENSG00000196712 ENSG00000292254 PMC3136877__F1 mTOR signaling cascade in the pathogenesis and prevention of skin cancer PMC9418006__F7 Metabolic pathways encoded by Comchoano-1 and Comchoano-2 consolidated from Pathway Tools ENSG00000112977 ENSG00000198125 PMC7912095__F2 Loss of LKB1 drives the tumor immune escape ENSG00000107562 PMC2926929__F1 The Effects of EPA, DHA, and Aspirin Ingestion on Plasma Lysophospholipids and Autotaxin ENSG00000198670 PMC8321592__F1 Cancer Genomic Profiling in Colorectal Cancer: Current Challenges in Subtyping Colorectal Cancers Based on Somatic and Germline Variants ENSG00000125398 ENSG00000157764 ENSG00000134982 ENSG00000168036 ENSG00000108375 ENSG00000121879 ENSG00000177084 PMC8461181__F3 GnIH in Biological Rhythms and Social Behaviors ENSG00000168036 PMC6957567__F1 Brief overview of DDR signalling ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000083093 ENSG00000138346 ENSG00000197299 ENSG00000051180 ENSG00000139618 PMC5123406__F1 Conceptual model of viral integration ENSG00000149311 ENSG00000175054 ENSG00000141867 ENSG00000051180 ENSG00000101425 PMC6299275__F3 Canonical pathway analysis using MetaCore identified EGFR, PDGFR, and mTOR signalling as the top 3 canonical pathways modulated in FCD type II patients ENSG00000101407 ENSG00000162889 ENSG00000140992 ENSG00000112964 ENSG00000138798 ENSG00000198793 ENSG00000155792 ENSG00000136869 ENSG00000175104 ENSG00000159335 ENSG00000146648 PMC4872954__F1 Obesity versus osteoarthritis: beyond the mechanical overload ENSG00000102871 ENSG00000172936 ENSG00000175104 ENSG00000127191 ENSG00000168610 PMC5833784__F2 Immunological consequences of kidney cell death ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC6856869__F4 Recognition of HSV-1 infection by pattern recognition receptors (PRRs) ENSG00000164430 ENSG00000163565 ENSG00000276561 PMC6765066__F7 HMGB1, a Nuclear Damage-Associated Molecular Pattern Molecule, in the Pathogenesis of Lung Diseases ENSG00000172005 ENSG00000189403 ENSG00000169429 ENSG00000136869 ENSG00000168610 PMC8897942__F1 MUC1 is a potential target to overcome trastuzumab resistance in breast cancer therapy ENSG00000198793 ENSG00000168036 ENSG00000168610 PMC8888544__F5 Gamma-tocotrienol, a radiation countermeasure, reverses proteomic changes in serum following total-body gamma irradiation in mice ENSG00000110944 ENSG00000169896 ENSG00000099985 ENSG00000100906 ENSG00000109320 ENSG00000113070 ENSG00000196954 ENSG00000173039 ENSG00000229314 ENSG00000106546 ENSG00000132170 ENSG00000163631 ENSG00000141867 ENSG00000110395 ENSG00000115415 ENSG00000177606 ENSG00000125538 ENSG00000184371 ENSG00000164400 ENSG00000136869 ENSG00000146648 PMC3532456__F3 Interleukin (IL)-13 and IL-4 signaling pathway ENSG00000123496 ENSG00000105397 ENSG00000131724 ENSG00000105639 ENSG00000168610 PMC3532456__F2 Transforming growth factor (TGF)B signaling pathway ENSG00000122194 PMC8471880__F2 Anti-Inflammatory Effect of Muscle-Derived Interleukin-6 and Its Involvement in Lipid Metabolism ENSG00000162711 ENSG00000168610 PMC6555274__F4 TGFB signalling pathway with FOXN3 ENSG00000049323 ENSG00000111537 ENSG00000095739 ENSG00000100387 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000053254 ENSG00000185591 ENSG00000164093 PMC7642035__F6 Therapeutic Interaction of WNT Pathway Activation and Asparaginase ENSG00000134982 ENSG00000168036 PMC4091806__F1 A New Lnc in Metastasis: Long Non-Coding RNA Mediates the Pro-metastatic Functions of TGFB ENSG00000169554 ENSG00000168610 PMC7094958__F2 RIG-I-like receptors: their regulation and roles in RNA sensing ENSG00000183735 ENSG00000088888 ENSG00000276561 PMC6642071__F1 Methionine–homocysteine cycle and biosynthesis of betaine ENSG00000148450 ENSG00000285250 ENSG00000291928 ENSG00000016391 PMC5331612__F1 ChREBP regulates fructolytic gene expression ENSG00000262785 ENSG00000138030 ENSG00000169710 PMC1183479__F8 Activation of protein synthesis in cardiomyocytes by the hypertrophic agent phenylephrine requires the activation of ERK and involves phosphorylation of tuberous sclerosis complex 2 (TSC2) ENSG00000198793 PMC7863575__F1 Steroidogenic pathway ENSG00000277893 ENSG00000203859 PMC7348953__F1 Therapeutic Targeting of the Wnt Signaling Pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000102312 ENSG00000168036 ENSG00000173273 PMC5267499__F1 Proteomics Analysis of Ovarian Cancer Cell Lines and Tissues Reveals Drug Resistance-associated Proteins ENSG00000002330 ENSG00000198793 ENSG00000127948 ENSG00000213523 PMC7094958__F4 RIG-I-like receptors: their regulation and roles in RNA sensing ENSG00000183735 ENSG00000088888 ENSG00000109606 ENSG00000135114 ENSG00000142405 ENSG00000083799 ENSG00000247315 ENSG00000121060 ENSG00000276561 ENSG00000101695 PMC5097370__F4 Regulation of myofibroblast formation by TGFB1 ENSG00000177606 PMC4435618__F2 Preclinical and Clinical Studies for Sodium Tungstate: Application in Humans ENSG00000198793 ENSG00000187840 PMC4435618__F1 Preclinical and Clinical Studies for Sodium Tungstate: Application in Humans PMC7918075__F4 Putative model for the involvement of cell signaling pathways in the induction of survival by type I (A/B) and II (G) IFNS in CLL cells ENSG00000105397 ENSG00000291971 ENSG00000168610 PMC4287622__F4 Protein Interactome of Muscle Invasive Bladder Cancer ENSG00000135446 ENSG00000177606 ENSG00000291748 ENSG00000146648 ENSG00000124762 ENSG00000137801 PMC8021683__F1 Summary of signaling pathways regulating cardiomyocyte proliferation ENSG00000129757 ENSG00000134982 ENSG00000168036 ENSG00000150457 ENSG00000178568 PMC4287622__F3 Protein Interactome of Muscle Invasive Bladder Cancer ENSG00000002330 ENSG00000058085 ENSG00000168036 ENSG00000091409 ENSG00000171791 ENSG00000112715 ENSG00000164305 ENSG00000124762 ENSG00000137801 ENSG00000053747 ENSG00000041982 ENSG00000128052 ENSG00000123374 ENSG00000026103 ENSG00000065361 ENSG00000198561 ENSG00000197565 ENSG00000073756 ENSG00000197461 ENSG00000065135 ENSG00000135446 ENSG00000067606 ENSG00000177606 ENSG00000146648 ENSG00000178568 PMC4538335__F1 Lesser-Known Molecules in Ovarian Carcinogenesis ENSG00000291971 ENSG00000198793 PMC2955921__F2 Scheme summarizing the differential effect of PARP-1 inhibition versus silencing on SSB repair via the BER pathway ENSG00000132646 ENSG00000116096 ENSG00000138385 PMC8008798__F1 General scheme illustrating the potential mechanistic pathway of Notch signaling in the pathogenesis of pulmonary fibrosis ENSG00000168214 ENSG00000283780 ENSG00000184384 ENSG00000196782 PMC8349779__F2 Reprogramming of TCA cycle, fatty acid and glutamine metabolism in renal cancer ENSG00000132382 ENSG00000136997 ENSG00000198670 ENSG00000115419 ENSG00000026103 PMC8349779__F1 Reprogramming of glucose transport and glucose metabolism in renal cancer ENSG00000173599 ENSG00000168610 PMC11663741__F10 Hypothesized immune mechanisms of fish spleen against N ENSG00000291603 ENSG00000166523 ENSG00000007312 ENSG00000288512 ENSG00000167996 ENSG00000197943 ENSG00000172936 ENSG00000180644 ENSG00000171608 ENSG00000123983 ENSG00000182326 PMC6592250__F5 Coordinated interactions between glycolysis, citrate cleavage enzyme, and glutaminolysis for the fatty acids biosynthesis in growing tumor cells ENSG00000112992 ENSG00000026103 PMC6283168__F3 Triacylglycerol (TAG) lipolysis in Drosophila: biochemistry and main regulatory pathways ENSG00000166819 ENSG00000160584 PMC7215558__F2 Autophagy and UPS alterations bridging altered proteostasis with neuroinflammation, the paradigm of protein glycation ENSG00000198793 PMC3439854__F2 Transcriptional regulation of PDPN expression ENSG00000115415 ENSG00000162493 ENSG00000125538 ENSG00000177606 ENSG00000168610 PMC6283168__F2 Triacylglycerol (TAG) synthesis in Drosophila: biochemistry and main regulatory pathways ENSG00000185813 ENSG00000158669 ENSG00000169710 ENSG00000198670 ENSG00000160216 ENSG00000062282 PMC12114829__F1 Biosynthesis of BRs in plants ENSG00000187475 ENSG00000150787 ENSG00000005381 PMC4580081__F2 Interactions of chaperone proteins with Stat3 panel (A) and Jak2 panel (B) ENSG00000105401 PMC6903413__F5 NFKB activation in inflammatory cells ENSG00000162711 ENSG00000150782 ENSG00000102871 ENSG00000172936 ENSG00000162692 ENSG00000127191 PMC6903413__F4 NFKB pathway in pancreatic acinar cells PMC4315934__F4 Cardiac muscle contraction and changes with exercise ENSG00000019991 ENSG00000285109 PMC3430718__F7 SOCS1 regulates the IFN but not NFKB pathway in TLR-stimulated human monocytes and macrophages ENSG00000172005 ENSG00000136869 ENSG00000125347 PMC3870464__F2 Protein components of the pheromone response network constructed by the PCST approach ENSG00000186635 ENSG00000130234 ENSG00000117399 PMC1133850__F10 Vaccinia virus-stimulated mitogen-activated protein kinase (MAPK) pathway is required for virus multiplication ENSG00000123268 PMC5114008__F2 Adaptive Stress Responses During Tumor Metastasis and Dormancy ENSG00000128272 ENSG00000144895 ENSG00000132478 PMC8276772__F1 Centric view of JAK/STAT5 in intestinal homeostasis, infection, and inflammation ENSG00000171476 ENSG00000101751 ENSG00000099985 ENSG00000181163 ENSG00000291971 ENSG00000198793 ENSG00000158806 ENSG00000012048 ENSG00000168283 ENSG00000198901 ENSG00000183734 ENSG00000138336 ENSG00000084676 ENSG00000102837 ENSG00000183337 ENSG00000149269 ENSG00000163914 ENSG00000196498 ENSG00000102974 PMC7181577__F7 Proposed effect of NgR reduction on APP traffic to lysosome through Rho/ROCK2 pathway ENSG00000169783 PMC8945922__F7 Chemotherapy Resistance: Role of Mitochondrial and Autophagic Components ENSG00000152348 ENSG00000156026 ENSG00000144848 ENSG00000145782 PMC4540028__F3 Comprehensive analyses of genomes, transcriptomes and metabolites of neem tree ENSG00000110921 ENSG00000196839 ENSG00000197429 PMC8945922__F5 Chemotherapy Resistance: Role of Mitochondrial and Autophagic Components ENSG00000128272 ENSG00000126775 ENSG00000144895 ENSG00000198793 ENSG00000144848 ENSG00000078237 PMC9652280__F4 Non-responsiveness to cardioprotection by ischaemic preconditioning in Ossabaw minipigs with genetic predisposition to, but without the phenotype of the metabolic syndrome ENSG00000213658 ENSG00000080823 PMC9663771__F2 Angiopoietins in Neovascular Diabetes-Related Retinal Diseases PMC8663872__F7 To explore the Radix Paeoniae Rubra-Flos Carthami herb pair's potential mechanism in the treatment of ischemic stroke by network pharmacology and molecular docking technology ENSG00000002330 ENSG00000070831 ENSG00000168040 ENSG00000150455 ENSG00000177455 ENSG00000226275 ENSG00000069482 ENSG00000213658 ENSG00000078747 ENSG00000111837 ENSG00000136997 ENSG00000198517 ENSG00000174197 PMC3428775__F3 Model depicting effects of Wnt-stabilized Beta-catenin through Tcf proteins in mESCs ENSG00000071564 PMC10468808__F2 Activation of NFKB and MAPK signaling pathways regulates the expression of catabolic factors ENSG00000175104 ENSG00000127191 PMC2727709__F1 Multiple previously established signaling cascades in activated mast cells with quantitative proteomic data from MCP5 cells represented as heatmap bars beside individual proteins ENSG00000033327 ENSG00000105397 ENSG00000291971 ENSG00000010810 ENSG00000173599 ENSG00000164399 ENSG00000010671 PMC7855580__F2 Systemic inflammatory response from SARS-Cov-2 may trigger atherosclerosis ENSG00000162711 PMC2795398__F1 Endotoxin binds to CD14 and Toll-like receptor 4 (TLR4) on the surface of monocytes and endothelial cells ENSG00000170458 ENSG00000172936 ENSG00000136869 PMC4110479__F3 Tolerogenic properties of plasmacytoid dendritic cells (pDCs) ENSG00000102962 ENSG00000239732 ENSG00000291971 ENSG00000145777 ENSG00000049768 ENSG00000168610 ENSG00000106546 PMC4110479__F2 Proinflammatory properties of plasmacytoid dendritic cells (pDCs) ENSG00000183735 ENSG00000239732 ENSG00000167207 ENSG00000105397 ENSG00000291971 ENSG00000125538 ENSG00000136869 ENSG00000106100 ENSG00000168610 ENSG00000276561 ENSG00000164342 PMC4428674__F1 Mediators released from activated MCs ENSG00000157404 ENSG00000049130 ENSG00000125538 PMC5814196__F1 Expression of Wnt-signaling pathway genes and their associations with miRNAs in colorectal cancer ENSG00000087095 ENSG00000281324 ENSG00000095739 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000196470 ENSG00000185269 PMC7533603__F4 Modeling the metabolic modifiers of T-cell function in Tconv and Treg, showing differential impacts of glycolysis and oxidative phosphorylation on each and the role of the mTOR pathway in mediating this ENSG00000141564 ENSG00000049768 PMC4295541__F2 Generation of ceramide and FTY720-P ENSG00000139624 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000143418 PMC8476624__F6 Investigation of proteins important for microcirculation using in vivo microdialysis after glucose provocation: a proteomic study ENSG00000113889 ENSG00000169814 ENSG00000228278 ENSG00000143839 ENSG00000081051 ENSG00000161031 ENSG00000229314 ENSG00000079557 ENSG00000106927 ENSG00000163631 ENSG00000180210 ENSG00000126218 ENSG00000138207 ENSG00000101981 ENSG00000121410 ENSG00000117601 ENSG00000145192 ENSG00000158874 ENSG00000168398 PMC8476624__F5 Investigation of proteins important for microcirculation using in vivo microdialysis after glucose provocation: a proteomic study ENSG00000113889 ENSG00000169814 ENSG00000228278 ENSG00000161031 ENSG00000229314 ENSG00000079557 ENSG00000106927 ENSG00000163631 ENSG00000117724 ENSG00000138207 ENSG00000121410 ENSG00000145192 ENSG00000158874 PMC5908130__F5 Perturbed gene network in placenta that may be reflected by the changes of circulating miRNAs in PTL ENSG00000041982 ENSG00000291971 ENSG00000010810 ENSG00000198793 ENSG00000128052 ENSG00000136997 ENSG00000277401 PMC2894843__F3 Ingenuity Pathway Assist (IPA) analysis of significant genes involved in cell death ENSG00000149311 ENSG00000150782 ENSG00000151490 ENSG00000172936 ENSG00000091106 ENSG00000168610 ENSG00000164305 PMC7324605__F5 Polyamine pathway in patients with Diffuse Cutaneous Leishmaniasis ENSG00000116649 ENSG00000102172 PMC8024183__F7 The differentially expressed genes mapped in p53 signalling pathway, which are upregulated after radiation exposure (highlighted in red) ENSG00000149311 ENSG00000175054 ENSG00000196839 ENSG00000145020 PMC8541835__F1 RNases H1 and H2: guardians of the stability of the nuclear genome when supply of dNTPs is limiting for DNA synthesis PMC6146604__F1 Lignin biosynthesis ENSG00000197713 ENSG00000062485 ENSG00000084774 PMC2746245__F2 Toll-like receptor (TLR) pathway ENSG00000187554 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000164342 PMC7744622__F4 Roles of p53 and PTEN signaling pathways in the regulation of autophagy ENSG00000177169 ENSG00000110497 ENSG00000123395 ENSG00000126775 ENSG00000198793 ENSG00000167965 ENSG00000078237 PMC7744622__F3 Major signaling pathways involved in the regulation of autophagy ENSG00000124102 ENSG00000177169 ENSG00000110497 ENSG00000127837 ENSG00000123395 ENSG00000126775 ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC8613976__F1 NLRP3 inflammasome activation in COVID-19: an interlink between risk factors and disease severity ENSG00000278718 ENSG00000162711 ENSG00000172936 PMC2746245__F6 Injury-induced changes in the nociceptive pathway ENSG00000186810 ENSG00000121807 ENSG00000196689 ENSG00000121966 PMC10519534__F8 DZP active constituents on myopia through the “AGE-RAGE diabetic complication signaling” pathway ENSG00000087245 ENSG00000135446 ENSG00000007908 ENSG00000168610 PMC7867275__F1 Heme synthesis pathway and mechanism of 5-aminolevulinic acid (5-ALA) fluorescence ENSG00000080819 ENSG00000118777 ENSG00000146648 PMC11171322__F8 Graphical overview of representative exclusively differentially expressed genes from our RNA sequencing data in the myeloid and lymphoid group that are clearly assigned to the BMP/TGFB signaling pathway ENSG00000105329 ENSG00000164761 ENSG00000120149 ENSG00000134871 ENSG00000168040 ENSG00000260001 ENSG00000029559 ENSG00000171812 ENSG00000188763 ENSG00000090376 ENSG00000184216 ENSG00000105723 ENSG00000127863 ENSG00000049089 PMC5790522__F7 Transcriptome profiling identified differentially expressed genes and pathways associated with tamoxifen resistance in human breast cancer ENSG00000101441 ENSG00000100485 ENSG00000096006 ENSG00000112038 ENSG00000149972 ENSG00000148082 ENSG00000146013 ENSG00000293532 ENSG00000157542 ENSG00000124102 ENSG00000087245 ENSG00000118402 ENSG00000182158 ENSG00000127955 ENSG00000257335 ENSG00000107175 ENSG00000156219 ENSG00000164742 ENSG00000146648 ENSG00000162104 ENSG00000185634 ENSG00000138083 ENSG00000291971 ENSG00000149782 ENSG00000105647 ENSG00000169032 ENSG00000155495 ENSG00000115290 ENSG00000179869 ENSG00000167536 ENSG00000162728 ENSG00000004478 ENSG00000159871 ENSG00000225556 ENSG00000103355 ENSG00000172382 ENSG00000005513 ENSG00000126803 ENSG00000129946 ENSG00000185591 ENSG00000164128 ENSG00000113070 ENSG00000169885 ENSG00000178363 ENSG00000165059 ENSG00000143933 ENSG00000182621 ENSG00000137841 ENSG00000087460 ENSG00000129007 ENSG00000014914 ENSG00000065135 ENSG00000117020 ENSG00000128272 ENSG00000174233 ENSG00000146592 ENSG00000177606 ENSG00000094755 ENSG00000060566 ENSG00000100985 ENSG00000143882 PMC7363309__F1 Utilizing cooled liquid chromatography and chemical derivatization to separate and quantify C3-epimers of 25-hydroxy vitamin D and low abundant 1A,25(OH)2D3: application in a pediatric population ENSG00000111012 ENSG00000019186 ENSG00000135929 PMC5382784__F1 Schematic illustration of extracellular oligopeptide metabolism in P ENSG00000197635 ENSG00000119383 ENSG00000176978 PMC8524104__F1 Lactate in the tumour microenvironment: From immune modulation to therapy ENSG00000198793 PMC3446895__F5 Arginine Consumption by the Intestinal Parasite Giardia intestinalis Reduces Proliferation of Intestinal Epithelial Cells ENSG00000116717 PMC7916160__F2 Overview of phosphatidylinositol-3-kinase (PI3K)/AKT/mTOR signaling pathway and inhibitors ENSG00000169047 PMC10915960__F1 Preconditioned mesenchymal stem cells with high therapeutic potential in various pathologies ENSG00000178860 PMC11841260__F3 Application of spatial transcriptomics to rheumatoid arthritis ENSG00000143546 ENSG00000149968 ENSG00000091972 ENSG00000078098 PMC9681882__F3 Plasma proteomic profiling in postural orthostatic tachycardia syndrome (POTS) reveals new disease pathways ENSG00000105664 ENSG00000189058 ENSG00000150656 ENSG00000113296 PMC7059589__F2 Neuronal roles of atypical protein kinases (aPKCs).(a) aPKCs mediates nerve growth factor (NGF) response ENSG00000144366 ENSG00000281324 ENSG00000162337 ENSG00000169047 ENSG00000198793 PMC8535591__F2 Insulin-like Growth Factor 1 Signaling in Mammalian Hearing ENSG00000177169 ENSG00000123395 ENSG00000002330 ENSG00000123374 ENSG00000140443 PMC6113426__F3 Summary of apolipoprotein B mRNA editing enzyme catalytic polypeptide‐like (APOBEC)3B transcriptional regulations in cancer cells ENSG00000104856 ENSG00000149311 ENSG00000175054 ENSG00000173599 ENSG00000205250 PMC7164249__F1 Merlin regulates different developmental signaling pathways ENSG00000070831 ENSG00000134982 ENSG00000168036 ENSG00000112851 ENSG00000146648 PMC2814006__F1 IL-1 and TNF signal transduction events ENSG00000102871 ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC4626744__F2 Enzymes involved in PGE2 synthesis and metabolism ENSG00000151632 ENSG00000188257 ENSG00000095303 ENSG00000148344 ENSG00000164120 ENSG00000073756 ENSG00000127472 ENSG00000187134 PMC4626744__F4 PGE2 synthesis, action, transport and metabolism in granulosa cells ENSG00000148344 ENSG00000174640 ENSG00000164120 ENSG00000073756 PMC9611771__F3 Identification of differentially expressed genes in mouse paraspinal muscle in response to microgravity ENSG00000142192 ENSG00000002330 ENSG00000069482 ENSG00000213658 ENSG00000178209 PMC4872542__F9 Local anesthetic bupivacaine induced ovarian and prostate cancer apoptotic cell death and underlying mechanisms in vitro ENSG00000132906 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC2882184__F1 Pathway analysis using all altered genes and proteins ENSG00000253293 ENSG00000168283 ENSG00000259207 ENSG00000105193 ENSG00000115415 ENSG00000168036 ENSG00000161970 ENSG00000162521 ENSG00000125347 ENSG00000146648 PMC3119709__F1 Macrophages as a Battleground for Toxoplasma Pathogenesis ENSG00000110944 ENSG00000120833 ENSG00000164400 ENSG00000118520 ENSG00000168610 PMC4383688__F1 Molecular Pathways: Aspirin and Wnt Signaling—A Molecularly Targeted Approach to Cancer Prevention and Treatment ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC8111291__F8 FOXC1 Negatively Regulates DKK1 Expression to Promote Gastric Cancer Cell Proliferation Through Activation of Wnt Signaling Pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8027476__F6 Schematic diatgram of CAFs induced renal cancer progression ENSG00000110711 ENSG00000291971 ENSG00000168610 ENSG00000106546 PMC5109916__F1 Probing the PI3K/Akt/mTor pathway using 31P-NMR spectroscopy: routes to glycogen synthase kinase 3 PMC4060523__F2 Signaling pathways that positively regulate ecdysteroidogenesis in the PG in Drosophila melanogaster PMC12239316__F6 Genetic model for evolution from all-black to all-white yak ENSG00000157404 ENSG00000080166 ENSG00000169032 ENSG00000107165 PMC8834284__F1 Characterization of Gfat1 (zeppelin) and Gfat2, Essential Paralogous Genes Which Encode the Enzymes That Catalyze the Rate-Limiting Step in the Hexosamine Biosynthetic Pathway in Drosophila melanogaster ENSG00000147162 ENSG00000013375 PMC4461826__F1 Mammalian cells employ two principal DNA double-strand break (DSB) repair pathways ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000083093 ENSG00000197299 ENSG00000051180 PMC6019448__F7 Avian and mammalian OASL involvement in RNase L and RIG-I signaling ENSG00000141527 ENSG00000088888 ENSG00000135114 ENSG00000135828 PMC3435458__F7 RGS10 exerts a neuroprotective role through the PKA/c-AMP response-element (CREB) pathway in dopaminergic neuron-like cells ENSG00000148908 ENSG00000102871 ENSG00000168040 PMC3258432__F6 Factors shown to promote or inhibit the vascular normalization phenotype in tumors ENSG00000145431 ENSG00000143248 ENSG00000170962 ENSG00000143878 ENSG00000198793 ENSG00000112715 ENSG00000146648 PMC7578900__F7 Signal pathway of PIO on mitochondria‐mediated apoptosis in cisplatin nephrotoxicity ENSG00000096717 PMC4564205__F3 Complete Genome Sequence of a High Lipid-Producing Strain of Mucor circinelloides WJ11 and Comparative Genome Analysis with a Low Lipid-Producing Strain CBS 277.49 ENSG00000110921 ENSG00000197713 ENSG00000122966 ENSG00000197429 ENSG00000113161 ENSG00000153574 ENSG00000167508 ENSG00000102977 ENSG00000067064 ENSG00000152904 ENSG00000173599 ENSG00000172005 ENSG00000162390 ENSG00000026103 ENSG00000062485 PMC2808176__F1 Example of pathway segments corresponding to FALZ identified from breast cancer data (Figure drawn with Cytoscape) ENSG00000116918 ENSG00000104365 ENSG00000065978 ENSG00000065361 ENSG00000276463 ENSG00000169047 ENSG00000100219 ENSG00000171791 ENSG00000134480 ENSG00000136936 ENSG00000104368 PMC2722219__F1 The TSC/mTOR signaling pathway ENSG00000169047 ENSG00000198793 ENSG00000196712 PMC6700727__F5 In vivo induction of demyelination by direct Mycobacterium leprae injection into sciatic nerves PMC8750547__F1 Long Noncoding RNAs Regulate the Inflammatory Responses of Macrophages ENSG00000172936 ENSG00000136869 ENSG00000079432 ENSG00000175104 PMC9367915__F2 Interplay of Developmental Hippo–Notch Signaling Pathways with the DNA Damage Response in Prostate Cancer ENSG00000149311 ENSG00000157554 ENSG00000175054 ENSG00000137601 ENSG00000148400 ENSG00000121067 ENSG00000150457 ENSG00000198586 PMC8308723__F1 Signaling Pathway and Transcriptional Regulation in Osteoblasts during Bone Healing: Direct Involvement of Hydroxyapatite as a Biomaterial ENSG00000170365 ENSG00000168036 PMC4652152__F8 Comparison of gene networks affected by ozone exposure in males and females ENSG00000163739 ENSG00000073756 ENSG00000277943 ENSG00000007171 ENSG00000150782 ENSG00000169245 ENSG00000226275 ENSG00000108691 ENSG00000111537 ENSG00000170458 ENSG00000187554 ENSG00000102245 ENSG00000163734 ENSG00000184371 ENSG00000084774 PMC4652152__F7 Ingenuity Pathway Analysis for inflammatory gene expression in females vs ENSG00000174125 ENSG00000239732 ENSG00000111537 ENSG00000154589 ENSG00000170458 ENSG00000136869 ENSG00000164342 PMC9367915__F1 Interplay of Developmental Hippo–Notch Signaling Pathways with the DNA Damage Response in Prostate Cancer ENSG00000149311 ENSG00000157554 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000101109 ENSG00000136997 ENSG00000150457 ENSG00000131023 ENSG00000139618 PMC2826600__F4 Insulin and IGF1 signaling pathway to promote glucose uptake by GluT3 in neurons (shown) or GlutT4 in muscle (not shown) ENSG00000198793 ENSG00000100979 ENSG00000079999 PMC11121248__F7 Two separate mechanisms for the role of MerTK and ENG in TNBC progression ENSG00000153208 ENSG00000136997 PMC5937133__F1 Type 1 diabetes pathogenesis and B cell protective factors ENSG00000111537 ENSG00000134982 PMC6163247__F2 Endoplasmic reticulum (ER) and mitochondria interactions ENSG00000110711 ENSG00000223802 ENSG00000172292 ENSG00000002330 ENSG00000156026 ENSG00000171791 PMC6163247__F1 Metabolic implications associated to ceramide synthesis ENSG00000135218 PMC7591521__F6 CsIVa-mediated inhibition of miR-155/GSK-3Beta-NFKB signaling pathway ENSG00000170458 ENSG00000125538 ENSG00000136869 PMC9343252__F7 MiR-146a targets CD147 in ALK+ ALCL promoting increased energy metabolism ENSG00000172216 ENSG00000168610 PMC9294232__F1 Research Progress on the Anticancer Activities and Mechanisms of Polysaccharides From Ganoderma ENSG00000149311 ENSG00000138798 ENSG00000170558 ENSG00000132646 ENSG00000123374 ENSG00000198890 ENSG00000175104 ENSG00000146648 PMC3805541__F3 MicroRNA Profiling in Prostate Cancer - The Diagnostic Potential of Urinary miR-205 and miR-214 ENSG00000100234 ENSG00000168209 ENSG00000157404 ENSG00000151726 ENSG00000102908 ENSG00000198793 ENSG00000007908 ENSG00000151615 ENSG00000112715 ENSG00000125686 ENSG00000100219 ENSG00000120075 ENSG00000162892 ENSG00000104081 PMC5482989__F7 Proposed mechanisms for crosstalk between AR and GDNF signaling and inhibition of prostate development by RET-mediated GDNF signaling PMC7843612__F6 TGFB pathway regulation by miR-331 ENSG00000118971 PMC6952807__F1 TNFR1-mediated survival and cell death pathways ENSG00000137275 ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000064012 ENSG00000285379 PMC6105893__F10 Role of cFP as a virulence factor while in the host and also as a signal to induce expression of genes to protect the pathogen ENSG00000047936 PMC4543283__F1 New pathway for memory B-cell activation in systemic lupus erythematosus (SLE) ENSG00000186716 PMC7504726__F2 Antioxidant effect of quercetin on enzyme activity, signal transduction pathways and reactive oxygen species (ROS) ENSG00000178573 PMC7367293__F4 Ingenuity pathway analysis (IPA) of actin cytoskeleton signaling in the Xenopus laevis whole brain after exposure to the predatory salamander larva, Hynobius lichenatus ENSG00000038382 ENSG00000142192 ENSG00000172380 ENSG00000175866 ENSG00000291971 ENSG00000134982 ENSG00000138443 ENSG00000138798 ENSG00000089159 PMC7367293__F6 CREB signaling in the Xenopus laevis whole brain after exposure to 24 h of a predation threat from the larval salamander, Hynobius lichenatus PMC3011108__F1 Schematic showing that when a cell membrane is injured the arachidonic acid pathway is activated to initiate the local inflammatory response through the production of prostaglandins, thromboxanes, and leukotrienes PMC5940296__F1 Latest advances in the interplay of physical and biochemical signaling pathways leading to transcription in the tumor microenvironment ENSG00000138757 ENSG00000136997 ENSG00000168036 ENSG00000162692 ENSG00000168646 PMC9096795__F5 Hereditary Systemic Autoinflammatory Diseases: Therapeutic Stratification ENSG00000093072 PMC11591163__F3 Mechanistic diagram of the Nrf-2/AREs signaling pathway ENSG00000181019 ENSG00000085662 ENSG00000079999 PMC11591163__F1 Blood–brain barrier is severely damaged during ischemic stroke ENSG00000151012 ENSG00000167468 ENSG00000197429 ENSG00000104549 ENSG00000179988 ENSG00000115107 PMC6357531__F3 Proposed model by which polyphenols may modulate oxidative stress-induced pathways including Ang II, VEGF and TNFA ENSG00000087245 ENSG00000198793 ENSG00000086991 ENSG00000100985 ENSG00000096717 PMC4920993__F2 Predicted FA and TAG biosynthetic pathways in perilla seeds ENSG00000173599 ENSG00000285482 ENSG00000198670 ENSG00000062282 PMC6397698__F4 Mechanism of action for combined TGFB and PD-1 pathway inhibition ENSG00000159128 ENSG00000111537 ENSG00000027697 PMC8349779__F5 Altered metabolic events in renal cell carcinoma (RCC) ENSG00000134086 ENSG00000145321 ENSG00000198670 PMC6321920__F1 HPV induces, yet tolerates, replication stress (RS) to promote viral replication through the ATR-dependent RS response ENSG00000132646 ENSG00000171848 ENSG00000123374 ENSG00000132510 PMC108819__F8 Signalling pathways for EGF activation of c-jun ENSG00000138798 ENSG00000291761 ENSG00000123268 PMC12029499__F1 Vitamin D synthesis and activation pathway ENSG00000111012 ENSG00000205221 ENSG00000019186 ENSG00000186104 PMC11694028__F3 Interaction of FBXW7 with signaling pathways and key molecules in gastrointestinal cancers ENSG00000182718 ENSG00000148400 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000123374 ENSG00000047849 ENSG00000146648 ENSG00000108061 ENSG00000109670 PMC3614663__F1 Diagram showing the crosstalk between the DNA damage response pathway and BMP-controlled osterix expression and osteoblast differentiation ENSG00000149311 ENSG00000170365 PMC6590643__F4 Simplified figure depicting the roles of RORC consensus pathway members, adapted from Yu et al ENSG00000110944 ENSG00000112116 ENSG00000105329 ENSG00000156127 ENSG00000137265 ENSG00000049768 ENSG00000168610 PMC2567351__F2 MAPK Signaling Pathway ENSG00000213658 PMC2567351__F1 T Cell Receiptor Signaling Pathway ENSG00000213658 ENSG00000135446 ENSG00000149308 PMC4684475__F2 Inflammatory targets of therapy in sickle cell disease ENSG00000102871 ENSG00000172936 PMC4238899__F1 Organisation and lineage control in the intestine ENSG00000183734 ENSG00000172238 PMC9498478__F5 Stress Response Mechanisms of Salmonella Enteritidis to Sodium Hypochlorite at the Proteomic Level ENSG00000257218 ENSG00000118520 ENSG00000150787 ENSG00000182263 PMC7582682__F1 On the hematopoietic cell surface, transient receptor potential cation channel subfamily M member 7 (TRPM7) and magnesium transporter 1(MagT1) facilitate magnesium influx into the cell ENSG00000092439 ENSG00000102158 ENSG00000132646 ENSG00000125538 ENSG00000198793 PMC4808760__F6 Kinetic models describing the in vivo metabolism of the HDL apolipoproteins on each HDL size fraction ENSG00000197713 ENSG00000110244 ENSG00000134982 ENSG00000158874 PMC5745449__F1 Modular Schema of the Stress Response Network ENSG00000198793 PMC12009910__F9 Notch signaling pathway: curcumin can bind Notch-1 protein and the bHLH domain of Hes1 ENSG00000135547 ENSG00000144485 ENSG00000179111 ENSG00000273529 ENSG00000114315 PMC12009910__F8 Research progress on the mechanism of curcumin anti-oxidative stress based on signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000276920 PMC6791470__F1 T Helper 9 Cells: A New Player in Immune-Related Diseases ENSG00000156127 ENSG00000150907 ENSG00000137265 ENSG00000107485 ENSG00000049768 PMC12009910__F3 Research progress on the mechanism of curcumin anti-oxidative stress based on signaling pathway ENSG00000157625 PMC3773342__F5 Genes expressed higher in mutant mice revealed networks of interacting genes ENSG00000019582 ENSG00000128016 ENSG00000185022 ENSG00000138792 ENSG00000177606 ENSG00000122877 ENSG00000086015 ENSG00000065802 PMC12009910__F2 Research progress on the mechanism of curcumin anti-oxidative stress based on signaling pathway ENSG00000181019 ENSG00000079999 PMC11130833__F1 Molecular activity of BTK- and BCL2- inhibitors in CLL ENSG00000095585 ENSG00000186716 ENSG00000198793 ENSG00000197943 ENSG00000171791 ENSG00000010671 PMC6475113__F5 EZH2 and Foxm1 as likely upstream regulators of PRLR-dependent gene expression ENSG00000001167 ENSG00000109906 ENSG00000105656 ENSG00000205250 ENSG00000145386 ENSG00000166851 ENSG00000104332 ENSG00000124762 ENSG00000064300 ENSG00000292210 ENSG00000114738 ENSG00000009709 ENSG00000102145 ENSG00000012048 ENSG00000072571 ENSG00000151702 ENSG00000288411 ENSG00000148773 ENSG00000164458 ENSG00000136997 ENSG00000130222 ENSG00000269404 ENSG00000154721 ENSG00000121621 ENSG00000162430 ENSG00000172530 ENSG00000274811 ENSG00000172238 ENSG00000023445 ENSG00000078399 ENSG00000088305 ENSG00000131747 ENSG00000178363 ENSG00000186111 ENSG00000121774 ENSG00000117724 ENSG00000288210 ENSG00000101004 ENSG00000136960 ENSG00000112984 ENSG00000134853 ENSG00000142731 ENSG00000178691 ENSG00000128709 ENSG00000090520 ENSG00000175305 ENSG00000113494 ENSG00000124783 PMC5003019__F8 HIV-1 Tat disrupts CX3CL1-CX3CR1 axis in microglia via the NFKB-YY1 pathway ENSG00000100811 ENSG00000168329 ENSG00000203710 PMC3773342__F9 Proposed signaling process for GDNF-independent UB outgrowth PMC5999746__F3 Reactive oxygen species (ROS) produce oxidative stress which in return converts the normal epithelium to early adenoma which leads to the next stage that is intermediate adenoma by the activation of EGFR signaling ENSG00000146648 PMC2443854__F1 The Essential Components of Nodal SignalingTGFB proteins are synthesized as pre-pro-proteins requiring cleavage of the signal peptide (black) and prodomain (orange) prior to dimerization of active ligand (red diamonds) ENSG00000160973 ENSG00000156574 ENSG00000130283 PMC3637951__F7 FOXM1’s role in thyroid cancer ENSG00000145604 ENSG00000134057 ENSG00000178999 ENSG00000166851 PMC8630372__F1 Clinical Development of AKT Inhibitors and Associated Predictive Biomarkers to Guide Patient Treatment in Cancer Medicine ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000121879 PMC9271868__F2 Regulatory Roles of Phospholipase A2 Enzymes and Bioactive Lipids in Mast Cell Biology ENSG00000087253 ENSG00000283887 ENSG00000226275 ENSG00000167323 ENSG00000293604 ENSG00000137055 PMC9271868__F1 Regulatory Roles of Phospholipase A2 Enzymes and Bioactive Lipids in Mast Cell Biology ENSG00000120436 ENSG00000087253 ENSG00000283887 ENSG00000226275 ENSG00000170775 ENSG00000165370 ENSG00000133067 ENSG00000173599 ENSG00000198670 PMC5991297__F7 Pro-inflammatory AGE-RAGE signaling is activated during arousal from hibernation in ground squirrel adipose ENSG00000102908 ENSG00000177606 ENSG00000189403 PMC2528845__F2 Intracellular signaling activated through FGFRs ENSG00000169291 PMC5991297__F1 AGE-RAGE signaling can activate ERK1/2 signaling ENSG00000102908 ENSG00000177606 ENSG00000189403 PMC9669388__F2 Astragalus and its formulas as a therapeutic option for fibrotic diseases: Pharmacology and mechanisms ENSG00000278718 ENSG00000162711 ENSG00000137033 ENSG00000148400 ENSG00000167468 ENSG00000168036 ENSG00000136869 ENSG00000133961 ENSG00000096717 ENSG00000079999 ENSG00000026103 PMC2528845__F4 Opposing signals regulate sex determination in the bipotential gonad ENSG00000162552 ENSG00000066468 ENSG00000125398 ENSG00000102678 PMC8046021__F1 Heparanase triggers multiple pathways that drive myeloma progression ENSG00000169245 ENSG00000019991 ENSG00000169047 ENSG00000173083 ENSG00000087842 PMC7720107__F5 TLR signaling adapter BCAP regulates inflammatory to reparatory macrophage transition by promoting histone lactylation ENSG00000172936 ENSG00000118520 PMC2891025__F6 Deep mRNA Sequencing for In Vivo Functional Analysis of Cardiac Transcriptional Regulators: Application to GAq ENSG00000175206 ENSG00000197893 ENSG00000118729 ENSG00000159388 ENSG00000174429 ENSG00000081189 ENSG00000120937 ENSG00000172037 ENSG00000159200 ENSG00000136026 ENSG00000103647 ENSG00000146648 ENSG00000143632 ENSG00000274137 PMC7000407__F2 Circadian rhythm in intervertebral disc degeneration: an autophagy connection ENSG00000177169 ENSG00000128272 ENSG00000144895 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC8692627__F6 Representative mechanisms of tsRNAs in malignancies ENSG00000163935 ENSG00000065978 ENSG00000159216 ENSG00000104290 ENSG00000100697 ENSG00000150457 ENSG00000184916 ENSG00000135341 ENSG00000123908 PMC8572706__F4 Therapeutic effects of Bombyx mori sericin on rat skin psoriasis through modulated epidermal immunity and attenuated cell proliferation ENSG00000213658 ENSG00000183979 ENSG00000177606 ENSG00000106546 ENSG00000069667 PMC5633085__F6 Tumor-induced osteomalacia ENSG00000118972 ENSG00000198793 ENSG00000077782 PMC6997863__F1 Different pathomechanisms linking DM and AD ENSG00000142192 PMC7442608__F4 Folate cycle is coupled to the methionine cycle through distinct mechanisms ENSG00000115902 ENSG00000092621 ENSG00000135069 ENSG00000163738 ENSG00000146733 PMC3957735__F2 Short-patch base excision repair pathway ENSG00000143799 ENSG00000132646 PMC7318773__F3 Maintenance of Foot-and-Mouth Disease Virus Persistence Inferred From Genes Differentially Expressed in Nasopharyngeal Epithelia of Virus Carriers and Non-carriers ENSG00000189377 ENSG00000087095 ENSG00000010818 ENSG00000127191 ENSG00000197885 ENSG00000183735 ENSG00000163141 ENSG00000161921 ENSG00000115415 ENSG00000281449 ENSG00000188211 ENSG00000183718 ENSG00000131323 ENSG00000175104 ENSG00000133135 PMC7761452__F2 Metazoan MOB proteins present extensive regulation between isotypes ENSG00000116641 ENSG00000130158 ENSG00000176390 ENSG00000073712 ENSG00000150457 ENSG00000166851 ENSG00000131023 PMC3767399__F4 The metabolic roles of the endosymbiotic organelles of Toxoplasma and Plasmodium spp ENSG00000144410 ENSG00000066926 ENSG00000126088 ENSG00000188690 PMC6290938__F10 Proposed mechanisms by which Adam8 deficiency in leukocytes and/or lung parenchymal cells leads to exaggerated cigarette smoke (CS)-induced chronic obstructive pulmonary disease in mice ENSG00000125538 ENSG00000146648 PMC9122509__F6 Prostate cancer pathway ENSG00000157554 ENSG00000002330 ENSG00000179091 ENSG00000184012 ENSG00000123374 ENSG00000171791 ENSG00000104368 PMC7926735__F1 Transforming growth factor B (TGFB) signaling regulation by actin remodeling induced by extracellular matrix (ECM) stiffness ENSG00000196588 ENSG00000174106 PMC10537408__F8 miRNAs in the HSV-2 infection of macrophages ENSG00000105397 ENSG00000198793 ENSG00000115904 PMC3153113__F7 Hypoxia Induced Energy Stress Regulates mRNA Translation and Cell Growth ENSG00000144895 ENSG00000198793 ENSG00000167658 PMC7441816__F2 PVAT regulates VSMC dilation and contraction ENSG00000100842 PMC11103502__F9 Pharmacological activation of the HIF pathway improves the ischemic tolerance of brain-resident cells by reprogramming of glucose metabolism PMC3687869__F2 Phosphatidylinositol-3-kinase/Akt signaling pathway ENSG00000002330 PMC11788444__F5 Crosstalk between dysregulation of metal ions and pathological proteins in neurodegenerative diseases ENSG00000142192 ENSG00000197386 ENSG00000185591 PMC11788444__F4 Iron dysregulation in the lysosome and mitochondria of PD ENSG00000116688 ENSG00000112561 ENSG00000181867 ENSG00000171109 PMC3134295__F1 Apoptotic Process ENSG00000120868 ENSG00000168040 PMC5127716__F4 Immune signaling cascades triggered by Cryptococcus neoformans recognition ENSG00000162711 ENSG00000187796 ENSG00000125538 ENSG00000197943 PMC6668592__F2A GC/MS and LC/MS-based Tissue Metabolomic Analysis Detected Increased Levels of Antioxidant Metabolites in Colorectal Cancer PMC7136162__F2 Prevention of atherothrombotic events in patients with diabetes mellitus: from antithrombotic therapies to new-generation glucose-lowering drugs ENSG00000003436 PMC6291828__F1 B cell receptor (BCR) signaling pathways ENSG00000177455 ENSG00000095585 ENSG00000167601 ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000198793 ENSG00000197943 ENSG00000010671 ENSG00000198286 PMC5366820__F2 PDK1 contributes to polarization of signaling downstream to PI3K during cell migration ENSG00000124181 PMC4327875__F2 Accredited translational medicine centre: Human renal fibrotic disease: Translational research at the Center for Cell Biology and Cancer Research (CCBCR), Albany Medical College, Albany, NY ENSG00000149311 ENSG00000105698 ENSG00000146648 PMC5496032__F7 Mechanisms on EET-mediated signaling in response to cardiac hypertrophy and fibrosis PMC7883590__F2 Myd88- and TRIF-Dependent Toll Like-Receptor 4 Inflammatory Signaling ENSG00000183735 ENSG00000170458 ENSG00000125538 ENSG00000172005 ENSG00000134070 ENSG00000136869 ENSG00000131323 ENSG00000175104 PMC99013__F3 Signal transduction cascades regulating pseudohyphal differentiation in S ENSG00000196511 ENSG00000070831 PMC6158335__F2 Accessory Toxins of Vibrio Pathogens and Their Role in Epithelial Disruption During Infection ENSG00000001626 PMC4650980__F1 Receptor tyrosine kinases and their targeted therapies in gastroesophageal cancers: EGFR, VEGFR and MET ENSG00000019991 ENSG00000138798 ENSG00000146648 PMC6889937__F5 Proposed action pathway through which Hnk protects cardio-myocytes against Dox-induced senescence ENSG00000162711 ENSG00000125538 ENSG00000265972 PMC6189490__F1 Salvage and de novo synthesis pathways for UTP synthesis ENSG00000094841 ENSG00000254550 PMC5357492__F1 Interactions of the AKT signaling pathway with the GSK3B signaling pathways ENSG00000134982 ENSG00000005882 ENSG00000168036 PMC6395781__F1 Mammalian O-mannosyl glycans: Biochemistry and glycopathology ENSG00000144647 ENSG00000185900 ENSG00000009830 ENSG00000130714 ENSG00000174684 ENSG00000181027 ENSG00000282880 PMC5852959__F6 CDK5RAP3 - AKT - GSK3B - Beta-catenin pathway in gastric cancer ENSG00000138795 ENSG00000168036 ENSG00000108465 PMC5545849__F1 TGFB signaling pathway ENSG00000070831 PMC2942073__F1 Genetics of Psychosis in Alzheimer Disease: A Review ENSG00000274542 ENSG00000137642 PMC11395074__F4 Schematic representation highlights how miRNAs involved in the metastatic process through modulation of key molecular pathways such as TGFB, PI3K/AKT, Wnt/Beta-catenin, JNK/STAT, and Hippo/YAP, which are vital for cancer cell invasion and migration ENSG00000182481 ENSG00000104221 ENSG00000085117 ENSG00000142178 ENSG00000148400 ENSG00000198561 ENSG00000124766 ENSG00000168036 ENSG00000067900 ENSG00000099942 ENSG00000168610 ENSG00000140807 ENSG00000169967 ENSG00000155011 ENSG00000196498 ENSG00000185591 ENSG00000168646 PMC11395074__F3 miRNAs play a pivotal role in maintaining the delicate balance between cell survival and death by modulating the activity of key pathways such as PI3K/AKT/mTOR, MAPK, TGFB, Wnt/Beta-catenin, and JAK/STAT ENSG00000169967 ENSG00000019991 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000168610 PMC2752373__F1 Selected transformation pathways of tamoxifen and the main CYP enzymes involved ENSG00000165841 ENSG00000197408 PMC5827395__F1 Evasion of the DNA-sensor-mediated IFN-I signal pathway by HSV-1 ENSG00000183735 ENSG00000164430 PMC8508636__F1 RNA Modifications and Epigenetics in Modulation of Lung Cancer and Pulmonary Diseases ENSG00000100234 ENSG00000163435 ENSG00000149658 ENSG00000198492 ENSG00000091542 ENSG00000174197 ENSG00000165819 ENSG00000107581 PMC5233495__F1 Canonical and non-canonical hippo pathway in ischemic heart disease ENSG00000186575 ENSG00000131023 PMC5636945__F1 Linear modules for conversion of glucose ENSG00000261701 ENSG00000030582 ENSG00000155657 PMC3103528__F5 Inhibitory Actions of Anti-Müllerian Hormone (AMH) on Ovarian Primordial Follicle Assembly ENSG00000111537 ENSG00000113558 ENSG00000152785 ENSG00000156574 ENSG00000185483 ENSG00000185591 ENSG00000137801 PMC6274944__F1 Schematic representation of the extracellular matrix (ECM) components implicated in the regulation of c-MET signaling ENSG00000019991 ENSG00000138798 ENSG00000146648 PMC7276298__F8 MnTE-2-PyP prevents myofibroblast formation ENSG00000181019 ENSG00000079999 PMC11620105__F7 Distribution of key targets in the PI3K/AKT signaling pathway ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000169047 PMC2259386__F1 Prototypical myelin-derived neurite growth inhibitors, their receptors and intracellular signaling pathway ENSG00000163914 ENSG00000169783 ENSG00000146648 PMC6722227__F3 Immunopathology of Trichomoniasis (TV) ENSG00000124107 PMC6021006__F6 Salidroside and liver fibrosis PMC7509416__F5 p38 functions in neurological and psychiatric disorders ENSG00000196689 PMC7593574__F2 Dab2 modulates inflammatory pathways in macrophages and dendritic cells ENSG00000182578 ENSG00000111537 ENSG00000291971 ENSG00000184371 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC3110060__F1 MicroRegulators come of age in senescence ENSG00000168283 ENSG00000135446 ENSG00000105810 ENSG00000096717 ENSG00000184216 ENSG00000175305 PMC7509416__F1 P38 MAP kinase signaling pathway ENSG00000132535 ENSG00000123268 PMC5748609__F3 ASFV entry and uncoating ENSG00000102189 ENSG00000149269 ENSG00000135404 ENSG00000146648 PMC3030591__F4 Comparative Transcriptomic Analysis of Uveal Melanoma and Normal Uveal Melanocyte ENSG00000172680 ENSG00000149930 ENSG00000138798 ENSG00000166484 ENSG00000099942 ENSG00000164305 ENSG00000178573 ENSG00000149269 ENSG00000276870 ENSG00000136997 ENSG00000125538 ENSG00000162889 ENSG00000087095 ENSG00000027075 ENSG00000104365 ENSG00000188386 ENSG00000115008 ENSG00000157764 ENSG00000254445 ENSG00000081189 ENSG00000120910 ENSG00000117020 ENSG00000128272 ENSG00000141480 ENSG00000067606 ENSG00000143507 ENSG00000177606 PMC3365480__F1 Pro- and anti-inflammatory effects of heat and heat shock proteins ENSG00000170458 ENSG00000125538 ENSG00000189403 ENSG00000175104 PMC3030591__F7 Comparative Transcriptomic Analysis of Uveal Melanoma and Normal Uveal Melanocyte ENSG00000149311 ENSG00000175054 ENSG00000123374 ENSG00000164305 ENSG00000164949 ENSG00000026103 PMC7237311__F5 Brain proteins identified to be interacting with GFP-CASK through GFP-Trap mass spectrometry analysis are plotted using the STRING database interface ENSG00000168807 ENSG00000147044 ENSG00000110711 ENSG00000230930 ENSG00000161682 ENSG00000108861 ENSG00000134982 ENSG00000176014 ENSG00000148943 ENSG00000136731 ENSG00000140323 ENSG00000092621 ENSG00000165023 ENSG00000113558 ENSG00000162521 ENSG00000014138 ENSG00000171533 ENSG00000119125 ENSG00000291368 PMC7060278__F4 KEGG maps analysis ENSG00000180210 ENSG00000134086 ENSG00000113456 ENSG00000182511 ENSG00000173156 ENSG00000172602 ENSG00000158825 ENSG00000198670 PMC3182762__F1 TLR signaling pathways ENSG00000150455 ENSG00000175104 ENSG00000276561 PMC7060278__F7 LPA metabolism, KLHL and KCNE3 as novel EMT controller genes ENSG00000129219 ENSG00000173599 ENSG00000197705 ENSG00000198670 ENSG00000158445 PMC8231117__F3 Irisin in Cancer Disease ENSG00000170558 ENSG00000198793 ENSG00000168610 PMC4518442__F3 Possible effects of soy isoflavone genistein and tea polyphenolic compound EGCG on the Wnt pathway in breast cancer stem cells ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC8231117__F2 Irisin in Cancer Disease ENSG00000170558 ENSG00000168610 PMC4440769__F11 TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation ENSG00000056558 ENSG00000157625 ENSG00000127191 PMC5833426__F7 Lenalidomide regulates CNS autoimmunity by promoting M2 macrophages polarization ENSG00000260314 ENSG00000118520 ENSG00000168610 PMC2820080__F5 Transcriptome Profiles of Carcinoma-in-Situ and Invasive Non-Small Cell Lung Cancer as Revealed by SAGE ENSG00000145194 ENSG00000175166 ENSG00000173599 ENSG00000104368 ENSG00000168490 PMC2820080__F4 Transcriptome Profiles of Carcinoma-in-Situ and Invasive Non-Small Cell Lung Cancer as Revealed by SAGE ENSG00000144063 ENSG00000160789 ENSG00000105835 ENSG00000090402 ENSG00000167720 ENSG00000148926 ENSG00000121807 ENSG00000119681 ENSG00000186847 ENSG00000141753 ENSG00000173599 ENSG00000174197 ENSG00000136235 ENSG00000105370 ENSG00000188505 ENSG00000151914 ENSG00000105427 ENSG00000024422 ENSG00000189001 ENSG00000145824 ENSG00000121552 ENSG00000124102 ENSG00000010327 ENSG00000175793 ENSG00000113140 ENSG00000100526 ENSG00000172889 ENSG00000156535 PMC11585160__F2 Smad5 Signal Path Diagram ENSG00000136997 ENSG00000283060 ENSG00000125968 PMC7563548__F11 Partial of the NRF2-mediated Oxidative Stress Response pathway in Fayoumi birds with acute heat stress ENSG00000077232 ENSG00000100302 ENSG00000177606 ENSG00000163017 ENSG00000140403 ENSG00000171608 ENSG00000077782 ENSG00000127948 ENSG00000101557 PMC7612652__F8 Graphical summary ENSG00000291971 ENSG00000146648 PMC12040833__F10 Pathways (Beta-alanine metabolic pathway; monoterpenoid biosynthesis pathway; glutathione metabolic pathway) enriched by differentially expressed genes (DEGs)/differentially abundant metabolites (DAMs) ENSG00000002549 PMC11787465__F4 Intricate signaling pathways and functional networks of miR-23 in tumor cell biology ENSG00000102962 ENSG00000107562 ENSG00000052802 ENSG00000115419 ENSG00000118946 ENSG00000079999 ENSG00000026103 PMC11787465__F5 Functional roles of miR-23 in organ development ENSG00000170961 ENSG00000198830 ENSG00000168036 ENSG00000106483 PMC7497309__F2 FOXO regulation by phosphorylation ENSG00000149269 ENSG00000123374 PMC11809362__F3 Major function of RECK: (A) RECK is a metal protease negative regulatory factor: (a) RECK binds to MT1-MMP and binds it to the GEEC-CLIC endocytic pathway for degradation ENSG00000087245 ENSG00000154764 ENSG00000168036 ENSG00000137845 PMC6714079__F4 Central carbon metabolism of T ENSG00000122966 ENSG00000172005 PMC11809362__F2 RECK as a Potential Crucial Molecule for the Targeted Treatment of Sepsis ENSG00000185591 PMC7456147__F1 Human placental chorionic villus showing the different trophoblast subtypes: vCTB, STB, and EVTs in the maternal decidua, the latter arising from differentiation of vCTB through the cell column ENSG00000102243 ENSG00000197905 ENSG00000206538 ENSG00000007866 ENSG00000074219 PMC9589499__F1 Isoniazid and rifampicin-induced liver injury and the effects of natural medicinal ingredients: A review ENSG00000181019 ENSG00000291971 ENSG00000125538 ENSG00000079999 PMC9589499__F3 Isoniazid and rifampicin-induced liver injury and the effects of natural medicinal ingredients: A review ENSG00000128272 ENSG00000125538 ENSG00000189403 ENSG00000026103 PMC7306093__F2 Schematic representation of Trp metabolism and its influence on Tregs ENSG00000089692 ENSG00000049768 ENSG00000106546 PMC5371856__F1 Outer membrane protein-mediated pathogenesis ENSG00000176597 ENSG00000146648 PMC7806375__F7 Working model of this study ENSG00000117020 ENSG00000168036 PMC6961090__F1 Epidermal growth factor receptor pathway and mechanism of action of osimertinib ENSG00000163235 ENSG00000138798 ENSG00000198793 ENSG00000168610 PMC5803867__F6 TLR4-NLRP3 inflammasome and PI3K/Akt signaling pathway ENSG00000162711 ENSG00000118777 PMC8220159__F2 Recent Advances in the Roles of Autophagy and Autophagy Proteins in Host Cells During Toxoplasma gondii Infection and Potential Therapeutic Implications ENSG00000177169 ENSG00000171791 PMC9270875__F2 Metabolic Requirements for Pathogen Response ENSG00000115419 PMC8351524__F9 Apolipoprotein C‐II induces EMT to promote gastric cancer peritoneal metastasis via PI3K/AKT/mTOR pathway ENSG00000087245 ENSG00000145321 ENSG00000100985 PMC7598617__F4 IL-17A as a Potential Therapeutic Target for Patients on Peritoneal Dialysis ENSG00000162711 ENSG00000205221 ENSG00000198793 ENSG00000049768 ENSG00000168610 PMC11831194__F3 Neuroprotective role of OPN in Alzheimer's disease pathology ENSG00000172936 PMC3543073__F2 Three examples of chromatin-modifying complexes and their mode of action ENSG00000198901 ENSG00000071655 ENSG00000143379 ENSG00000196591 ENSG00000140320 ENSG00000134046 PMC9312354__F7 N6-Methyladenosine Methylome Profiling of Muscle and Adipose Tissues Reveals Methylase–mRNA Metabolic Regulatory Networks in Fat Deposition of Rex Rabbits ENSG00000145388 ENSG00000101474 ENSG00000011566 ENSG00000150907 ENSG00000047188 ENSG00000165269 ENSG00000168610 ENSG00000000005 PMC3543073__F4 Bacterial nucleomodulins targeting chromatin ENSG00000140320 PMC5868510__F5 The molecular mechanism by which miR-134 aggravates atherogenesisMiR-134 downregulates ANGPTL4 expression by directly binding to the 3′UTR of ANGPTL4, leading to increased expression and activity of LPL ENSG00000167772 PMC9515028__F2 Possible role of long non-coding RNAs in recurrent miscarriage ENSG00000150782 ENSG00000259207 ENSG00000088836 ENSG00000168036 ENSG00000169429 ENSG00000123374 PMC4654680__F1 Emerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancer ENSG00000186575 ENSG00000109321 ENSG00000089685 ENSG00000144560 ENSG00000019549 ENSG00000150457 ENSG00000132849 ENSG00000114019 ENSG00000227345 ENSG00000089225 PMC11060011__F8 Molecular action schematic ENSG00000168958 ENSG00000050165 ENSG00000168036 ENSG00000196628 ENSG00000165819 PMC4654680__F4 Emerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancer ENSG00000186575 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC4910294__F2 Differentially expressed proteins involved in the pathway of Alzheimer׳s disease ENSG00000132906 ENSG00000142192 ENSG00000002330 ENSG00000168040 ENSG00000119912 ENSG00000164305 PMC12164340__F6 Alpha-Linolenic Acid from Zanthoxylum Seed Powder Regulates Fatty Acid Metabolism and Influences Meat Quality of Pekin Duck via the ADIPOQ/AMPK/CPT‑1 Pathway ENSG00000135218 PMC5808733__F7 Activation of the JAK-STAT pathway by viruses and the biogenesis, fission and fusion life cycle of mitochondria ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC8548342__F5 MinION sequencing from sea ice cryoconites leads to de novo genome reconstruction from metagenomes ENSG00000128602 ENSG00000143631 ENSG00000127948 PMC3669661__F2 Phosphatidic Acid and Lipid Sensing by mTOR ENSG00000173599 ENSG00000198670 PMC3669661__F1 Phosphatidic Acid and Lipid Sensing by mTOR ENSG00000198793 PMC5204211__F1 The status of Nrf2-based therapeutics: current perspectives and future prospects ENSG00000178573 ENSG00000100387 ENSG00000156273 ENSG00000079999 PMC3408695__F1 Part of the metabolic pathway of estradiol and the role of various enzymes involved: Estradiol is metabolized into 2-hydroxyestradiol (2-OHE2) and 4-hdroxyestradiol (4-OHE2) by CYP1A1 and CYP1B1 respectively ENSG00000181019 ENSG00000140465 PMC2806519__F8 Prostaglandin F2Alpha-F-prostanoid receptor regulates CXCL8 expression in endometrial adenocarcinoma cells via the calcium–calcineurin–NFAT pathway ENSG00000159200 ENSG00000169429 ENSG00000117602 PMC3369817__F8 Pathway diagram of the cyanobacterial core metabolic network ENSG00000197713 ENSG00000122966 ENSG00000172005 ENSG00000062485 PMC7290734__F2 Type 2 immune response via ILC2s in asthma patients ENSG00000137033 ENSG00000145777 ENSG00000166090 PMC6099186__F2 The role played by TCL1 in multiple signaling pathways ENSG00000149311 ENSG00000186716 ENSG00000198793 ENSG00000100219 ENSG00000010671 PMC3777916__F3 Using Biological Pathway Data with Paxtools ENSG00000197713 ENSG00000153574 PMC3777916__F2 Using Biological Pathway Data with Paxtools ENSG00000078369 ENSG00000186469 PMC3247963__F7 Model illustrating that early and late ISGs induction is regulated by multiple STAT1 posttranslational modifications ENSG00000105397 ENSG00000142166 PMC5745837__F7 Molecular interactions in the Akt/mTOR signaling pathway.IP3K: Inositol-triphosphate 3-kinase; PDK: phosphoinositide-dependent kinase; TSC: tuberous sclerosis complex; Rheb: Ras homolog enriched in brain; mTOR: mammalian target of rapamycin ENSG00000198793 ENSG00000166278 PMC8708596__F4 An Insight on Novel Molecular Pathways in Metastatic Prostate Cancer: A Focus on DDR, MSI and AKT PMC25571__F9 A model of cnxPg action ENSG00000071564 ENSG00000134982 PMC9198215__F2 Sirtuins in Osteogenic Differentiation of Vascular Smooth Muscle Cells and Vascular Calcification ENSG00000149311 ENSG00000168036 ENSG00000077463 ENSG00000096717 ENSG00000142082 PMC3165779__F3 Cellular PA-interaction networks ENSG00000182481 ENSG00000000419 ENSG00000185215 ENSG00000149084 ENSG00000122218 ENSG00000169710 ENSG00000107862 ENSG00000148175 ENSG00000144021 ENSG00000184432 ENSG00000106305 ENSG00000184575 ENSG00000253729 ENSG00000086200 ENSG00000064419 ENSG00000119705 ENSG00000155229 ENSG00000105438 ENSG00000102900 ENSG00000198561 ENSG00000197102 ENSG00000065559 ENSG00000083312 ENSG00000130227 ENSG00000174903 ENSG00000101161 ENSG00000115415 ENSG00000197879 ENSG00000146648 ENSG00000132341 PMC7839487__F1 Intermediate filaments cross talk with different signaling pathways ENSG00000178860 ENSG00000134982 ENSG00000168036 ENSG00000131095 PMC6288394__F1 Summary of the potential mechanisms of vaccine NSEs ENSG00000167207 ENSG00000125538 ENSG00000198793 PMC3764329__F2 Metabolic pathways for fatty acid and acetate utilization ENSG00000062485 PMC10965438__F13 Nanomaterials modulating TAMs polarization for the treatment of pancreatic cancer ENSG00000177575 ENSG00000214285 ENSG00000136869 ENSG00000171791 PMC6188698__F1 Regulation of Neurogenesis by DISC1 ENSG00000166579 ENSG00000149557 ENSG00000168036 ENSG00000168646 PMC10965438__F15 Macrophage membrane-coated nanomaterials and macrophage-based microrobot for the treatment of digestive system tumor ENSG00000198793 ENSG00000214285 ENSG00000189403 ENSG00000146648 PMC6190866__F6 Differentially regulated genes by IRF7 overexpression upon H6N2 infection ENSG00000121989 ENSG00000184254 ENSG00000157933 ENSG00000140044 ENSG00000176692 ENSG00000172216 ENSG00000105808 ENSG00000111837 ENSG00000259330 ENSG00000244462 ENSG00000125968 ENSG00000172201 ENSG00000169218 ENSG00000154736 ENSG00000189184 ENSG00000131095 ENSG00000154016 ENSG00000052802 ENSG00000166033 ENSG00000091073 ENSG00000160752 ENSG00000154856 ENSG00000133110 ENSG00000108924 ENSG00000050165 ENSG00000115266 ENSG00000198517 ENSG00000146122 ENSG00000048052 ENSG00000198355 ENSG00000128965 PMC5834288__F5 Myostatin regulates phosphorylation of key enzymes in glycogen metabolism and glycolysis pathway ENSG00000104812 ENSG00000130957 ENSG00000108515 ENSG00000068976 ENSG00000149269 ENSG00000102893 ENSG00000067177 ENSG00000152556 PMC8168458__F1 Crosstalk between metabolic pathways and the tissues in which they are implicated in aging regulation ENSG00000171105 ENSG00000105835 ENSG00000169047 ENSG00000096717 ENSG00000105662 PMC6642871__F2 The glycolytic switch in different cell types ENSG00000198793 PMC7531435__F1 Key Figure ENSG00000163914 ENSG00000139116 PMC8301451__F1 Dual Roles of the Activin Signaling Pathway in Pancreatic Cancer ENSG00000170365 ENSG00000137834 ENSG00000177606 ENSG00000132478 PMC4975146__F3 Signal transducer and activator of transcription tyrosine kinase domain c-Kit in cancer cell.Notes: The Ras-Erk pathway, PI3K/AKT pathway, and Src-signaling pathway have been demonstrated in this schematic picture ENSG00000120833 ENSG00000291971 ENSG00000171791 PMC7585454__F3 Myocardial Phosphodiesterases and their Role in cGMP Regulation ENSG00000138735 ENSG00000116741 ENSG00000137672 ENSG00000115271 ENSG00000138741 PMC4975146__F2 Signal transducer and activator of transcription tyrosine kinase domain c-Kit in normal cell.Notes: Ras/Erk pathway directs to activate of the proliferation genes ENSG00000198793 PMC2666391__F2 Toll-Like Receptors and Corneal Innate Immunity ENSG00000226275 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC6058517__F1 Schematic representation of the rough PTX-PLGA-MS fabrication technique, tumor site injection and intracellular drug delivery pathway ENSG00000134057 PMC5624538__F1 Role of FXR in Liver Inflammation during Nonalcoholic Steatohepatitis ENSG00000148346 ENSG00000108691 ENSG00000081041 PMC4077879__F1 Selective autophagy against membranous compartments ENSG00000126775 ENSG00000023287 ENSG00000116209 PMC1892626__F3 Regulation of hypoxia-inducible factor-1A (HIF-1A) and drug interventions currently in use ENSG00000134086 ENSG00000198793 ENSG00000146648 ENSG00000121966 PMC11677460__F10 Hypothetical model ENSG00000178860 ENSG00000151012 PMC7734207__F2 Schematic diagram of the regulation of mitochondrial apoptosis, Wnt/Beta-catenin, JAK-STAT, and PI3K/AKT signaling pathways via different miRNAs in various human cancers ENSG00000159128 ENSG00000002330 ENSG00000115415 ENSG00000134982 ENSG00000174804 ENSG00000165879 ENSG00000168036 ENSG00000027697 ENSG00000120868 ENSG00000168610 ENSG00000196628 PMC5520878__F8 Schematic diagram illustrating signaling of EZH2 and its upstream activator and its downstream effectors in GC ENSG00000185591 PMC11814426__F1 miMOMP activates mtDNA-cGAS-STING pathway and promotes cellular senescence and tissue aging ENSG00000115008 PMC7963035__F1 NAD+ metabolism and its roles in cellular processes during ageing ENSG00000187531 ENSG00000105835 ENSG00000180773 ENSG00000221955 ENSG00000278488 ENSG00000262217 ENSG00000077463 ENSG00000103257 ENSG00000142082 ENSG00000172940 ENSG00000283100 ENSG00000157064 ENSG00000124523 ENSG00000173614 ENSG00000122696 ENSG00000008130 ENSG00000096717 ENSG00000089163 PMC2711774__F2 Proposed biosynthetic pathway for the disorazoles ENSG00000134575 ENSG00000014257 PMC2888641__F1 Targeting Hedgehog - a Cancer Stem Cell Pathway ENSG00000106571 ENSG00000128602 PMC7880682__F6 Effect of curcumin mediated by PPARa in mouse liver ENSG00000039537 PMC6858476__F1 Schematic overview of steroidogenesis and corresponding urine steroid metabolites ENSG00000086696 ENSG00000203859 ENSG00000179142 ENSG00000127948 ENSG00000176387 PMC3411916__F3 [LM5]Strategies for treatment of traumatic central nervous system (CNS) injuries ENSG00000198793 PMC4852799__F1 Appropriate activation and feedback control of TP53 activity is critical to effective tumor suppression ENSG00000149311 ENSG00000175054 PMC11506335__F3 Comparison of ATR activation and signaling pathway in interphase and in mitosis ENSG00000175054 ENSG00000164053 ENSG00000143971 PMC10215119__F1 Mechanisms involved in the regulation of macrophage polarization by exosomal ncRNA in AS ENSG00000160179 ENSG00000168610 ENSG00000136826 PMC9231089__F15 Sorafenib Chemosensitization by Caryophyllane Sesquiterpenes in Liver, Biliary, and Pancreatic Cancer Cells: The Role of STAT3/ABC Transporter Axis ENSG00000291971 ENSG00000138798 ENSG00000184207 ENSG00000168610 ENSG00000146648 PMC8097443__F7 Ethylzingerone, a Novel Compound with Antifungal Activity ENSG00000074800 ENSG00000164778 PMC3787764__F8 Proposed molecular pathway governing multiciliogenesis ENSG00000171444 ENSG00000129654 PMC9312280__F4 Evaluation of Proanthocyanidins from Kiwi Leaves (Actinidia chinensis) against Caco-2 Cells Oxidative Stress through Nrf2-ARE Signaling Pathway ENSG00000178573 ENSG00000079999 PMC5731897__F3 Transcriptomic pathway analysis of urokinase receptor silenced breast cancer cells: a microarray study ENSG00000027075 ENSG00000170961 ENSG00000105835 ENSG00000157764 ENSG00000011422 ENSG00000149968 ENSG00000198561 ENSG00000148926 ENSG00000140092 ENSG00000073756 ENSG00000168610 ENSG00000171388 PMC6028781__F4 Central carbon and nitrogen metabolism of Arabidopsis thaliana active in most growth stages and conditions simulated ENSG00000159224 ENSG00000122966 ENSG00000172005 PMC4925073__F1 Pathway of codeine metabolism in a CYP2D6 extensive metabolizer ENSG00000171234 PMC7531435__F3 Integrins Control Vesicular Trafficking; New Tricks for Old Dogs ENSG00000133961 PMC8254040__F1 Crosstalk between nucleocytoplasmic trafficking and the innate immune response to viral infection ENSG00000047410 ENSG00000111581 ENSG00000138750 ENSG00000124789 ENSG00000101146 ENSG00000108559 ENSG00000030066 ENSG00000102900 ENSG00000163002 ENSG00000095319 ENSG00000139496 ENSG00000126883 ENSG00000058804 ENSG00000155561 ENSG00000113569 ENSG00000196313 ENSG00000132661 ENSG00000110713 ENSG00000125450 ENSG00000069248 ENSG00000213024 ENSG00000132341 PMC3492658__F1 NOD1 and NOD2 signaling pathways and interaction partners ENSG00000112977 ENSG00000162711 ENSG00000088888 ENSG00000167207 ENSG00000187796 ENSG00000125538 ENSG00000145782 ENSG00000106100 ENSG00000057663 PMC4846800__F2 Resistance mechanisms in MAPK-inhibitor treated melanoma ENSG00000157764 ENSG00000140379 ENSG00000135446 ENSG00000123374 ENSG00000196712 PMC4379579__F9 Fate of plasmids and their expressed antigens after electroporation (A); The Fas/FasL signaling pathway and some of the key molecules involved (B) ENSG00000134982 ENSG00000168040 ENSG00000026103 PMC4258820__F1 Representative ARG biosynthesis routes in prokaryotes ENSG00000122966 ENSG00000038002 PMC3260860__F6 Scheme of the EGR-1/GGPPS/ERK 1/2 pathway PMC7593815__F2 Illustration of the cellular context and key processes in which MPEG1 is implicated ENSG00000111537 ENSG00000172936 PMC11653477__F1 Physical exercise-mediated neuroprotective mechanisms in Parkinson's disease, Alzheimer's disease, and epilepsy ENSG00000096717 ENSG00000079999 PMC3021368__F5 Foxo3 controls DCs functions ENSG00000163599 ENSG00000171791 PMC8661833__F2 Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity ENSG00000154059 ENSG00000173976 ENSG00000076716 ENSG00000164342 PMC3943226__F1 Apoptosis signaling pathway ENSG00000067900 ENSG00000171791 ENSG00000115760 ENSG00000084774 PMC10478613__F2 Structure and function of kartogenin ENSG00000159216 ENSG00000168036 ENSG00000067955 PMC8732860__F7 Inhibition of HMGB1 Ameliorates the Maternal-Fetal Interface Destruction in Unexplained Recurrent Spontaneous Abortion by Suppressing Pyroptosis Activation ENSG00000278718 ENSG00000162711 ENSG00000189403 PMC6769940__F1 Interference of hepatitis C virus (HCV) with the nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2)/ Keap1-signaling pathway ENSG00000197930 ENSG00000178573 ENSG00000169047 ENSG00000198793 ENSG00000130649 ENSG00000140443 ENSG00000079999 PMC6613992__F1 Endogenous oxalate synthesis pathway in hepatocytes PMC4762423__F1 Metabolism reprogramming in PDAC ENSG00000065833 ENSG00000197713 ENSG00000198380 ENSG00000136997 ENSG00000153574 PMC8739690__F5 Transcriptomics analysis reveals the signal transduction mechanism of brassinolides in tea leaves and its regulation on the growth and development of Camellia sinensis ENSG00000110934 ENSG00000102034 ENSG00000163166 PMC5784953__F7 Critical comparison of topology-based pathway analysis methods ENSG00000140992 ENSG00000002330 ENSG00000157764 ENSG00000101109 ENSG00000138798 ENSG00000115904 ENSG00000121879 ENSG00000100485 ENSG00000068028 ENSG00000163235 ENSG00000166501 ENSG00000197943 ENSG00000124181 ENSG00000146648 PMC9302576__F1 Metabolic Reprogramming Induces Macrophage Polarization in the Tumor Microenvironment ENSG00000115415 ENSG00000134070 ENSG00000136869 ENSG00000168610 PMC4130202__F2 New molecules targeting angiogenesis and crosstalks between angiogenesis and tumor microenvironment ENSG00000112715 PMC309687__F10 Postsenescence survival in telomerase-deficient (tlc1Δ) budding yeast cells is controlled by three distinct Rad52-based homologous recombination pathways ENSG00000136425 ENSG00000051180 PMC1782192__F2 Direct and indirect activation of human natural killer (NK) cells ENSG00000164342 PMC3854201__F4 Biological interaction networking of PSME1 and RPS12 in chronic atrophic gastritis (CAG) ENSG00000157764 ENSG00000261857 ENSG00000125538 ENSG00000263528 ENSG00000198734 ENSG00000112306 PMC4675703__F1 Therapeutic control of complement activation at the level of the central component C3 ENSG00000166278 ENSG00000062485 PMC5193490__F2 Nrf2 affects mitochondrial function at multiple levels ENSG00000065833 ENSG00000026103 PMC9160246__F3 Neuroinflammation in PD ENSG00000125538 PMC6928941__F2 Ca2+ is mostly involved in mTOR-independent autophagy induction ENSG00000110497 ENSG00000205221 ENSG00000126775 ENSG00000198793 ENSG00000112561 PMC6166529__F1 Cancer Genome Atlas of glioblastoma multiforme ENSG00000135446 ENSG00000134853 ENSG00000105810 ENSG00000118971 ENSG00000146648 ENSG00000139687 ENSG00000196712 ENSG00000198625 PMC7405025__F2 Pathogenesis and management of myocardial injury in coronavirus disease 2019 ENSG00000108691 ENSG00000130234 ENSG00000184012 PMC9160246__F9 Mechanistic view of roles of different K+-channels in the diagnosis and treatment of the PD pathogenesis ENSG00000177606 ENSG00000127948 PMC3368264__F1 An overview of the folate metabolism pathway in formation of essential intermediates in Leishmania ENSG00000228716 PMC11013124__F1 Neuroinflammation of Microglial Regulation in Alzheimer’s Disease: Therapeutic Approaches ENSG00000162711 ENSG00000198793 PMC7699002__F1 Sulfur Metabolism Under Stress ENSG00000182511 ENSG00000116761 ENSG00000116984 PMC9650603__F2 FOXK2 transcription factor and its roles in tumorigenesis (Review) ENSG00000163930 ENSG00000138336 ENSG00000177606 ENSG00000196591 ENSG00000168036 ENSG00000141568 ENSG00000169375 ENSG00000164105 PMC10760828__F9 Schematic representation of overall outcome of the study ENSG00000067066 ENSG00000140464 PMC8001769__F2 Schematic view of controlling cancer hallmarks and associated signaling pathway by lncRNAs ENSG00000149311 ENSG00000198793 ENSG00000140443 PMC6497095__F9 Schematic view of signaling events elicited by LPS in RPE cells ENSG00000129219 ENSG00000197713 ENSG00000173599 PMC5006627__F1 Interaction between the canonical WNT signaling pathway and other signaling pathways implicated in MPNST tumorigenesis ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000089685 ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000121966 ENSG00000173273 PMC11351389__F3 Mechanistic Insights and Therapeutic Strategies in Osteoporosis: A Comprehensive Review ENSG00000178860 ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000168646 PMC11641583__F2 YAP activation in KCs ENSG00000182718 ENSG00000109321 ENSG00000291971 ENSG00000134757 ENSG00000197905 ENSG00000081277 ENSG00000007866 ENSG00000150457 ENSG00000134760 ENSG00000131023 ENSG00000136826 ENSG00000291442 ENSG00000074219 ENSG00000117713 ENSG00000186081 ENSG00000186575 ENSG00000144283 ENSG00000186847 ENSG00000146648 ENSG00000154096 PMC4344549__F1 Canonical Wnt signaling ENSG00000281324 ENSG00000134982 ENSG00000168036 PMC4440880__F1 Activation and targeting of prosurvival pathways mediating FLT3 resistance ENSG00000122025 ENSG00000107562 ENSG00000198793 ENSG00000137193 ENSG00000121966 PMC9459503__F6 Histone methyltransferase KMT2D mediated lipid metabolism via peroxisome proliferator-activated receptor gamma in prostate cancer ENSG00000131473 ENSG00000169710 PMC11351389__F2 Mechanistic Insights and Therapeutic Strategies in Osteoporosis: A Comprehensive Review ENSG00000118972 ENSG00000242252 ENSG00000291837 PMC5343023__F3 Fatty acid (FA) and cholesterol sensing in T cell immune responses ENSG00000049768 PMC9236130__F1 Autotaxin/Autotaxin-Lysophosphatidic Acid Axis in the Initiation and Progression of Liver Cancer ENSG00000163914 ENSG00000198670 PMC8762220__F2 Altered BMP2/4 Signaling in Stem Cells and Their Niche: Different Cancers but Similar Mechanisms, the Example of Myeloid Leukemia and Breast Cancer ENSG00000178860 ENSG00000122691 ENSG00000148175 PMC9005057__F1 SI-MOIRAI: a new method to identify and quantify the metabolic fate of nucleotides ENSG00000291814 ENSG00000120885 PMC2918880__F1 Schematic depiction of selected core elements of the unfolded protein response (UPR), featuring the components measured herein (; ; ; ) ENSG00000144895 ENSG00000100219 ENSG00000171791 PMC5528145__F2 Mechanistic association of insulin signaling with mitochondrial function in normal and diabetic brain ENSG00000096717 ENSG00000105723 PMC3021368__F2 PI3K in immune system ENSG00000177455 ENSG00000186716 PMC8966389__F3 Zika Virus Neuropathogenesis: The Different Brain Cells, Host Factors and Mechanisms Involved ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000134057 ENSG00000142166 PMC11641583__F3 YAP and TAZ interactions with signalling pathways and TFs ENSG00000167601 ENSG00000281324 ENSG00000109321 ENSG00000291971 ENSG00000144560 ENSG00000168036 ENSG00000002745 ENSG00000090932 ENSG00000136826 ENSG00000066468 ENSG00000170365 ENSG00000141867 ENSG00000124216 ENSG00000171631 ENSG00000019549 ENSG00000164690 ENSG00000146648 ENSG00000102974 PMC9236130__F2 Autotaxin/Autotaxin-Lysophosphatidic Acid Axis in the Initiation and Progression of Liver Cancer ENSG00000019991 ENSG00000291971 ENSG00000198793 ENSG00000198670 ENSG00000064547 ENSG00000171517 ENSG00000087077 ENSG00000168610 PMC5585656__F1 Proposed role of molecular and small molecule chaperones in proteostasis PMC9159919__F7 Acute Intoxication With Alcohol Reduces Trauma-Induced Proinflammatory Response and Barrier Breakdown in the Lung via the Wnt/Beta-Catenin Signaling Pathway ENSG00000134982 ENSG00000167941 ENSG00000163739 ENSG00000168036 PMC9340220__F1 Antioxidants in Human Milk on Bronchopulmonary Dysplasia Prevention and Treatment: A Review ENSG00000079387 ENSG00000181019 ENSG00000096717 PMC5519008__F2 lumpGEM: Systematic generation of subnetworks and elementally balanced lumped reactions for the biosynthesis of target metabolites ENSG00000065833 ENSG00000122966 ENSG00000196839 ENSG00000172005 ENSG00000082212 ENSG00000062485 PMC3116598__F1 p21-activated kinases in Erbb2-positive breast cancer ENSG00000198793 ENSG00000136997 PMC3467778__F3 Skewed Th17/Treg cell differentiation in patients with BD, a hypothesis ENSG00000049768 ENSG00000168610 PMC2992967__F2 Sonic hedgehog (SHH) pathway ENSG00000106571 ENSG00000095739 ENSG00000115457 ENSG00000136997 ENSG00000164690 ENSG00000104332 ENSG00000114315 ENSG00000128602 PMC5894198__F8 Schematic diagram of GDF15 activating the PI3K/AKT and MAPK pathway in cervical cancer progression ENSG00000135446 ENSG00000136997 ENSG00000123374 ENSG00000130513 PMC8304001__F1 Prostate Cancer Therapy Enzalutamide Compared with Abiraterone Acetate/Prednisone Impacts Motivation for Exploration, Spatial Learning and Alters Dopaminergic Transmission in Aged Castrated Mice PMC10869801__F0 Macrophage TSC1-mediated AKT/MST1/NRF2 signaling pathway in I/R-triggered liver inflammation ENSG00000189403 ENSG00000136869 ENSG00000175104 ENSG00000079999 PMC6052671__F1 TGFB1 signaling cascade leading to EMT ENSG00000170558 ENSG00000001626 PMC2849646__F3 Frequent amplification and overexpression of multiple EGFR-family-signaling components in non-small cell lung cancer (NSCLC) ENSG00000146648 ENSG00000160691 PMC11609662__F8 Metabolic pathway map of detected metabolites ENSG00000254550 ENSG00000026103 PMC6044387__F5 The two co-occurring pathways in PDAC that are predicted to drive oncogenesis based on the mutational landscape representing two common driver pathways ENSG00000124102 ENSG00000157764 ENSG00000065361 ENSG00000122733 ENSG00000198793 ENSG00000141564 ENSG00000171791 ENSG00000118971 ENSG00000121879 ENSG00000149311 ENSG00000012048 ENSG00000136997 ENSG00000134853 ENSG00000105810 ENSG00000116690 ENSG00000064012 ENSG00000139687 ENSG00000178568 ENSG00000198625 PMC6044387__F6 MAPK heat diffusion sub-network: pathway extracted from the TieDIE subnetwork using heat diffusion analysis from the MAPK1 network node ENSG00000162889 ENSG00000100906 ENSG00000147168 ENSG00000135439 ENSG00000109320 ENSG00000138798 ENSG00000095015 ENSG00000115904 ENSG00000173039 ENSG00000281877 ENSG00000162772 ENSG00000105639 ENSG00000010671 ENSG00000160691 ENSG00000177455 ENSG00000107295 ENSG00000177189 ENSG00000171720 ENSG00000110395 ENSG00000177606 ENSG00000100784 ENSG00000146648 PMC5079184__F3 IL-15 functions as a danger signal to regulate tissue-resident T cells and tissue destruction ENSG00000105639 ENSG00000168610 PMC8388923__F7 Nepetoidin B from Salvia plebeia R. Br. Inhibits Inflammation by Modulating the NFKB and Nrf2/HO-1 Signaling Pathways in Macrophage Cells ENSG00000079999 PMC10618387__F5 Crosstalk between the signaling pathway of pyroptosis, apoptosis, and autophagy ENSG00000278718 ENSG00000162711 ENSG00000198793 ENSG00000285069 PMC8515020__F1 Hyperinflammatory Immune Response and COVID-19: A Double Edged Sword ENSG00000278718 ENSG00000162711 ENSG00000108691 ENSG00000111537 ENSG00000108688 ENSG00000189403 ENSG00000136869 ENSG00000164342 PMC3317017__F4 Altered signaling pathways and inhibitors ENSG00000134982 ENSG00000164690 ENSG00000128602 ENSG00000146648 PMC8637543__F2 Zinc Finger Proteins in Neuro-Related Diseases Progression ENSG00000080822 ENSG00000127528 ENSG00000099326 PMC10618387__F3 Apoptosis is mediated by intrinsic and extrinsic pathways ENSG00000278718 ENSG00000002330 ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000026103 PMC2665727__F5 Ty retrotransposition cycle ENSG00000236826 ENSG00000170860 ENSG00000138231 ENSG00000130332 ENSG00000130520 ENSG00000164167 ENSG00000114127 ENSG00000172795 PMC8194305__F4 Therapeutic Landscape of Rheumatoid Arthritis: Current State and Future Directions ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000102871 ENSG00000172936 ENSG00000168404 ENSG00000105639 ENSG00000175104 ENSG00000127191 ENSG00000168610 ENSG00000115594 ENSG00000163702 PMC6823372__F3 KEGG pathways involved in the lipid methabolism of zebrafish enriched after MPs exposure ENSG00000112977 PMC6322225__F2 Health to disease (HTD) network ENSG00000213658 ENSG00000101213 PMC6834863__F2 The different apelinergic signaling pathways ENSG00000117525 ENSG00000130234 ENSG00000128052 ENSG00000112715 ENSG00000142082 PMC4594611__F1 Hypothetical Model for the Transduction of Synaptic Stimuli to Long-Term Plasticity ENSG00000143799 ENSG00000101751 ENSG00000198793 PMC4409285__F1 Schematic intracellular network required for lipid metabolism, Apo B biogenesis, and CM assembly in the enterocyte ENSG00000042832 ENSG00000120437 PMC8745771__F3 Rigosertib and Cholangiocarcinoma: A Cell Cycle Affair ENSG00000166851 PMC6268691__F1 Biosynthesis pathway for gangliosides ENSG00000257218 ENSG00000069482 ENSG00000111728 PMC7483331__F2 Protein signaling networks regulating autophagy ENSG00000123395 ENSG00000291971 ENSG00000135404 ENSG00000145782 ENSG00000168610 PMC1555658__F2 Cholesterol precursors and facial clefting ENSG00000164690 ENSG00000128602 PMC2922518__F1 Schematic illustration depicting the cellular pathways that lead to eIF4E activation and phosphorylation by Mnk1/2 ENSG00000163435 ENSG00000108691 ENSG00000149968 ENSG00000108688 ENSG00000100985 PMC4211376__F7 DAPK2 is a novel modulator of TRAIL-induced apoptosis ENSG00000120868 ENSG00000168040 PMC8745771__F1 Rigosertib and Cholangiocarcinoma: A Cell Cycle Affair ENSG00000134982 ENSG00000166851 ENSG00000117399 PMC5709754__F1 CD30 mediates its effects through a number of diverse signaling pathways, which in concert confer a survival benefit to the cells on which CD30 is upregulated ENSG00000056558 ENSG00000127191 PMC8534091__F1 Intersection of Purine and Mitochondrial Metabolism in Cancer ENSG00000128050 ENSG00000125166 ENSG00000100714 ENSG00000198931 PMC6877939__F1 Overview of PI3K/AKT/mTOR signaling pathway and downstream effects ENSG00000124102 ENSG00000146648 PMC6918475__F1 Bile acids in glucose metabolism and insulin signalling — mechanisms and research needs ENSG00000167910 ENSG00000180432 ENSG00000115271 PMC3403084__F5 Necrosis signaling pathways ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 PMC9331965__F1 IRIDA Phenotype in TMPRSS6 Monoallelic-Affected Patients: Toward a Better Understanding of the Pathophysiology ENSG00000010704 ENSG00000106327 ENSG00000178752 ENSG00000168610 PMC5393505__F3 Network of damaging mutations in ACC associates to the TP53 pathway ENSG00000186575 ENSG00000106123 ENSG00000147601 ENSG00000072422 ENSG00000126778 PMC2808316__F5 Metabolic model for Aspergillus niger ENSG00000148798 ENSG00000172005 PMC5715147__F1 Schematic of albumin/AlbiVax nanocomplexes for efficient vaccine delivery and combination cancer immunotherapy ENSG00000134982 PMC10528955__F1 Neuroinflammation: A Modifiable Pathway Linking Obesity, Alzheimer’s disease, and Depression ENSG00000042832 ENSG00000125538 ENSG00000136869 PMC11083345__F5 DEGs and DEPs involved in Alpha-linolenic acid metabolism, terpenoid biosynthesis and phenylalanine metabolism pathway ENSG00000167508 PMC5997167__F3 Gene networks involved in the analyses of males with HCB exposure ENSG00000277258 ENSG00000102977 PMC3065826__F1 Metabolism, Cell Surface Organization, and Disease ENSG00000069482 ENSG00000131446 ENSG00000168282 ENSG00000152127 ENSG00000146648 PMC5997167__F5 Networks involved in the analyses involving males with nPFOS exposure ENSG00000136541 ENSG00000111300 ENSG00000078579 ENSG00000169891 ENSG00000147133 ENSG00000234545 ENSG00000126467 ENSG00000075240 ENSG00000147082 ENSG00000139687 ENSG00000122042 PMC3546058__F1 DNA Sequence Variants in PPARGC1A, a Gene Encoding a Coactivator of the omega-3 LCPUFA Sensing PPAR-RXR Transcription Complex, Are Associated with NV AMD and AMD-Associated Loci in Genes of Complement and VEGF Signaling Pathways ENSG00000142192 ENSG00000000971 ENSG00000132170 PMC8836889__F1 Promoting Apoptosis, a Promising Way to Treat Breast Cancer With Natural Products: A Comprehensive Review ENSG00000149311 ENSG00000120868 ENSG00000171791 PMC2517789__F2 Two pathways from gp130 to hypertrophic gene expression ENSG00000115415 ENSG00000128342 ENSG00000168610 PMC2517789__F1 Cytokines and their receptors in cardiovascular diseases ENSG00000145623 ENSG00000099985 ENSG00000242689 ENSG00000122756 ENSG00000128342 PMC8807626__F3 Context-dependent modulation of TGFB pathway by LRG1 ENSG00000170365 PMC8745569__F1 Intriguing Thyroid Hormones–Lung Cancer Association as Exemplification of the Thyroid Hormones–Cancer Association: Three Decades of Evolving Research ENSG00000198793 ENSG00000103316 PMC8836889__F5 Promoting Apoptosis, a Promising Way to Treat Breast Cancer With Natural Products: A Comprehensive Review ENSG00000171791 PMC8836889__F3 Promoting Apoptosis, a Promising Way to Treat Breast Cancer With Natural Products: A Comprehensive Review ENSG00000198793 ENSG00000171791 PMC8836889__F2 Promoting Apoptosis, a Promising Way to Treat Breast Cancer With Natural Products: A Comprehensive Review ENSG00000168040 ENSG00000026103 PMC7925333__F3 Major intestinal host defense pathways identified in C. elegans ENSG00000169136 ENSG00000112561 ENSG00000170653 ENSG00000100219 PMC3116140__F2 The core pathway of Notch signaling ENSG00000168214 ENSG00000273529 ENSG00000133961 ENSG00000114315 PMC5893262__F3 TCR complex activation ENSG00000213658 PMC3542954__F1 Epstein-Barr virus interactions with the Bcl-2 protein family and apoptosisEBV infection disrupts normal cell death and survival pathways in various human tumor cells, including lymphocytes, fibroblasts, and epithelial cells ENSG00000019582 ENSG00000111537 ENSG00000186716 ENSG00000171791 ENSG00000026103 PMC4670612__F10 Ingenuity Pathway Analysis of the subset of day-one genes that differentiate long-term success or failure, divided into two groups (F and G) following an unsupervised cluster analysis ENSG00000129437 ENSG00000196705 ENSG00000139985 ENSG00000180210 ENSG00000164338 ENSG00000111726 ENSG00000181045 ENSG00000150991 ENSG00000136997 ENSG00000128510 ENSG00000139687 ENSG00000291941 ENSG00000197587 ENSG00000159348 ENSG00000154144 ENSG00000162408 ENSG00000153015 ENSG00000197121 ENSG00000141314 ENSG00000162510 ENSG00000105642 ENSG00000166801 ENSG00000178401 ENSG00000198792 ENSG00000159147 ENSG00000138660 ENSG00000156110 ENSG00000276276 PMC8147474__F3 Maintenance of Skeletal Muscle to Counteract Sarcopenia in Patients with Advanced Chronic Kidney Disease and Especially Those Undergoing Hemodialysis PMC9389749__F1 Transfection with Plasmid-Encoding lncRNA-SLERCC nanoparticle-mediated delivery suppressed tumor progression in renal cell carcinoma ENSG00000168283 ENSG00000205277 ENSG00000112715 PMC9586778__F4 Network Pharmacology-Based Exploration on the Intervention of Qinghao Biejia Decoction on the Inflammation-Carcinoma Transformation Process of Chronic Liver Disease via MAPK and PI3k/AKT Pathway ENSG00000142192 ENSG00000005339 ENSG00000291971 ENSG00000112715 ENSG00000121879 ENSG00000168610 ENSG00000146648 PMC6363635__F1 Pathways to DHT synthesis (modified from Ref ENSG00000135437 ENSG00000086696 ENSG00000108786 ENSG00000151632 ENSG00000073737 PMC9370349__F1 Alleviating Effects of Black Soybean Peptide on Oxidative Stress Injury Induced by Lead in PC12 Cells via Keap1/Nrf2/TXNIP Signaling Pathway ENSG00000265972 ENSG00000079999 PMC6621164__F9 Model of the function of CTTNBP2 at dendritic spines ENSG00000291971 PMC8125491__F3 Epigenetic Regulation of Neuroinflammation in Parkinson’s Disease PMC6131612__F1 PI3K/Akt signaling pathway in HI ENSG00000198793 ENSG00000171791 PMC5923353__F1 Lytic cycle proteins contribution to tumor initiation and tumor maintenance through enhanced survival, inflammation and immunomodulation ENSG00000107562 ENSG00000125538 ENSG00000121966 PMC6147765__F3 Different modalities of cell death ENSG00000152348 ENSG00000150782 ENSG00000167468 ENSG00000163914 ENSG00000144848 ENSG00000168040 ENSG00000145782 ENSG00000164305 ENSG00000057663 ENSG00000026103 PMC3247287__F8 Profiling Insulin Like Factor 3 (INSL3) Signaling in Human Osteoblasts ENSG00000133105 ENSG00000291971 ENSG00000149782 ENSG00000168036 PMC5597216__F1 Pituitary genomic expression profiles of steers are altered by grazing of high vs. low endophyte-infected tall fescue forages ENSG00000145681 ENSG00000069482 ENSG00000291972 ENSG00000084676 ENSG00000146469 ENSG00000115138 ENSG00000170893 ENSG00000112715 ENSG00000101680 PMC3863956__F1 Using PainNetworks to reproduce the NGF-TrkA signalling pathway ENSG00000167941 ENSG00000160691 PMC6937654__F1 miRNAs regulate the HSC activation and schistosomiasis liver fibrosis through modulating TGFB/SMAD signaling pathway ENSG00000105329 ENSG00000291748 PMC10473946__F1 Impact of inhaled and intranasal corticosteroids on glucose metabolism and diabetes mellitus: A mini review ENSG00000167772 ENSG00000169047 ENSG00000145321 PMC7895386__F5 Wide range of metabolic adaptations to the acquisition of the Calvin cycle revealed by comparison of microbial genomes ENSG00000122966 ENSG00000172005 PMC8145311__F7 Distinguishing Alzheimer’s Disease Patients and Biochemical Phenotype Analysis Using a Novel Serum Profiling Platform: Potential Involvement of the VWF/ADAMTS13 Axis ENSG00000049323 ENSG00000091010 ENSG00000030582 ENSG00000142798 ENSG00000135439 ENSG00000134569 ENSG00000110799 ENSG00000080345 ENSG00000203710 ENSG00000119681 ENSG00000166716 ENSG00000281244 ENSG00000138744 ENSG00000088247 ENSG00000182463 ENSG00000168807 ENSG00000163399 ENSG00000140678 ENSG00000151461 ENSG00000167491 ENSG00000102699 ENSG00000118503 ENSG00000144857 ENSG00000288142 ENSG00000138303 ENSG00000163872 ENSG00000116584 ENSG00000230031 ENSG00000083799 ENSG00000102974 PMC8890945__F6 Inhibitory effect on melanogenesis via PKA/CREB/MITF axis by DPN PMC11885516__F2 Dual role of reactive astrocytes ENSG00000169071 ENSG00000148400 ENSG00000114315 ENSG00000115594 PMC8876623__F1 mTOR Signaling and Potential Therapeutic Targeting in Meningioma ENSG00000186575 ENSG00000155792 ENSG00000026508 ENSG00000167965 PMC4646847__F4 Oligonucleotide discriminators of the TLR9-cholinergic links ENSG00000114200 ENSG00000239732 ENSG00000087085 PMC8111166__F2 Kynurenine pathway ENSG00000183077 PMC6021586__F5 Potential effects of miR-143 and miR-135a on signaling pathways ENSG00000291363 ENSG00000107485 ENSG00000131724 PMC7879635__F9 Signaling pathways affected by exosomal miR-199a-3p/145-5p ENSG00000139193 ENSG00000110395 ENSG00000010278 ENSG00000135404 PMC8073974__F7 Curcumin Inhibits Lysophosphatidic Acid Mediated MCP-1 Expression via Blocking ROCK Signalling ENSG00000198670 PMC8237754__F1 Epigenetic Regulation of Autophagy Beyond the Cytoplasm: A Review ENSG00000141867 ENSG00000150907 ENSG00000096717 PMC4754913__F3 Diagram summarizing the reviewed mechanisms by which CCR9 induces different aspects of tumor metastasis ENSG00000131142 PMC8960601__F2 Immunomodulatory Activity of Mesenchymal Stem Cells in Lupus Nephritis: Advances and Applications ENSG00000178860 ENSG00000108691 ENSG00000168610 ENSG00000121966 PMC4318143__F8 A Dlg5-mediated bifurcation in Smo activity during Hh response ENSG00000143147 ENSG00000274429 ENSG00000106571 ENSG00000166813 ENSG00000128602 PMC5182003__F2 AKT signaling pathway map ENSG00000132906 ENSG00000157404 ENSG00000002330 ENSG00000163235 ENSG00000134982 ENSG00000198793 ENSG00000136997 ENSG00000026508 ENSG00000168036 ENSG00000146648 PMC2759144__F4 Model depicting the E2Fs-FA/BRCA axis in the control of cell fate ENSG00000012048 ENSG00000144554 ENSG00000181544 ENSG00000187790 ENSG00000115392 ENSG00000187741 ENSG00000112039 ENSG00000158169 PMC5574030__F1 An overview of central carbon metabolism ENSG00000062485 ENSG00000084774 PMC7817765__F1 Activation pattern of NF-KB pathway in lung cell lines infected with SARS-CoV-2 ENSG00000104365 ENSG00000117020 ENSG00000226275 ENSG00000110330 ENSG00000170458 ENSG00000109320 ENSG00000177606 ENSG00000169032 ENSG00000164342 PMC11914309__F9 Differentially expressed genes in TNF Signaling Pathway (rno04668) using transcriptomic data at 168 h after TMT administration ENSG00000102871 ENSG00000177606 ENSG00000213341 ENSG00000083799 ENSG00000168040 PMC11914309__F7 Differentially expressed genes in Chemokine Signaling Pathway (rno04062) using transcriptomic data at 168 h after TMT administration ENSG00000002330 ENSG00000169032 ENSG00000099942 PMC4754913__F2 Diagram summarizing the reviewed mechanisms by which CCR9 induces different aspects of tumor chemoresistance ENSG00000198793 ENSG00000168036 PMC5796186__F1 Malignant pleural mesothelioma disease progression ENSG00000145041 ENSG00000163930 ENSG00000186575 ENSG00000106571 ENSG00000102312 ENSG00000026508 ENSG00000168036 ENSG00000150457 ENSG00000128602 ENSG00000131023 PMC8565650__F4 Polyphenols as Antitumor Agents Targeting Key Players in Cancer-Driving Signaling Pathways ENSG00000169047 PMC10308129__F7 Krüppel-like factor 10 (KLF10) as a critical signaling mediator: Versatile functions in physiological and pathophysiological processes ENSG00000163083 ENSG00000155090 PMC8583909__F1 Effect of Epigallocatechin-3-Gallate on EGFR Signaling and Migration in Non-Small Cell Lung Cancer ENSG00000138798 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC6417506__F3 Chemical induction of proximity is sufficient for the regulation of diverse cellular processes ENSG00000167986 ENSG00000139842 ENSG00000113851 PMC10308129__F4 Krüppel-like factor 10 (KLF10) as a critical signaling mediator: Versatile functions in physiological and pathophysiological processes ENSG00000170365 ENSG00000142611 ENSG00000155090 PMC4973703__F2 Main lipid classes and biochemical pathways involved in the production of TAG in developing seeds ENSG00000173599 ENSG00000198670 PMC5709591__F5 Interactome of negatively and positively changed genes comparing differentiated NIKS with differentiated NIKS16 cells ENSG00000110944 ENSG00000100234 ENSG00000284774 ENSG00000134533 ENSG00000105329 ENSG00000072274 ENSG00000124107 ENSG00000171791 ENSG00000166484 ENSG00000112715 ENSG00000010671 ENSG00000106546 ENSG00000163631 ENSG00000057149 ENSG00000134086 ENSG00000077150 ENSG00000144802 ENSG00000137265 ENSG00000168310 ENSG00000136235 ENSG00000082556 ENSG00000162892 ENSG00000196712 ENSG00000136158 ENSG00000152266 ENSG00000087245 ENSG00000177575 ENSG00000147437 ENSG00000155827 ENSG00000274205 ENSG00000129911 ENSG00000186827 ENSG00000153208 ENSG00000175193 ENSG00000134013 ENSG00000152669 ENSG00000163131 ENSG00000152804 ENSG00000140743 ENSG00000114166 PMC10308129__F2 Krüppel-like factor 10 (KLF10) as a critical signaling mediator: Versatile functions in physiological and pathophysiological processes ENSG00000078747 ENSG00000177606 ENSG00000196470 ENSG00000155090 PMC6060409__F2 Innate immune response to RSV: Advances in our understanding of critical viral and host factors ENSG00000213928 ENSG00000088888 ENSG00000115415 ENSG00000172936 ENSG00000136869 PMC3432348__F1 Pathways activating and inhibiting complement ENSG00000039537 ENSG00000113600 ENSG00000203710 ENSG00000166278 ENSG00000236625 PMC3899953__F6 A model for the role of ATP-mediated interaction between Rtg2 and Mks1 in ATP homeostasis ENSG00000011143 PMC3263309__F1 Notch, Wnt, and Hedgehog signaling pathways regulate normal and stem cell fate ENSG00000283780 ENSG00000134982 ENSG00000136997 ENSG00000026508 ENSG00000168036 ENSG00000128602 PMC6627707__F1 Biogenesis of extracellular vesicles (EVs) carrying micro RNAs (miRNAs) in viral infection ENSG00000110651 ENSG00000010278 ENSG00000135404 PMC2949777__F5 JAK/STAT pathway in infected EPCs ENSG00000068079 ENSG00000213928 ENSG00000115415 ENSG00000033800 PMC6701977__F3 Adenocarcinoma genotypes encode for transformation via the Ras pathway supported by the calcium pathway and the integrator complex ENSG00000179344 ENSG00000123104 ENSG00000146143 ENSG00000124762 ENSG00000111247 PMC7527139__F1 Summary of metabolic networks in iFermCell215 ENSG00000122966 ENSG00000171444 ENSG00000172005 PMC9205143__F2 Long non-coding RNA MIR4435-2HG: a key molecule in progression of cancer and non-cancerous disorders ENSG00000170558 ENSG00000124766 PMC9205143__F4 Long non-coding RNA MIR4435-2HG: a key molecule in progression of cancer and non-cancerous disorders ENSG00000058091 PMC8533303__F6 Anticancer Targets and Signaling Pathways Activated by Britannin and Related Pseudoguaianolide Sesquiterpene Lactones ENSG00000198793 ENSG00000136997 PMC5191957__F2 Carcinogenic Effects of Oil Dispersants: a KEGG Pathway-based RNA-seq Study of Human Airway Epithelial Cells ENSG00000023445 ENSG00000104365 ENSG00000005961 ENSG00000100906 ENSG00000173039 ENSG00000091409 ENSG00000162924 ENSG00000213341 ENSG00000134871 ENSG00000164171 ENSG00000121879 ENSG00000076604 ENSG00000053747 ENSG00000136997 ENSG00000175104 ENSG00000139687 PMC7313573__F1 Figures show the metabolism and role of biotin, cobalamin, and pyridoxine in various pathways ENSG00000123454 PMC8753429__F6 Ginsenoside Rh2 reduces depression in offspring of mice with maternal toxoplasma infection during pregnancy by inhibiting microglial activation via the HMGB1/TLR4/NFKB signaling pathway ENSG00000189403 ENSG00000172936 ENSG00000136869 PMC9092887__F10 miR-23b-3p rescues cognition in Alzheimer’s disease by reducing tau phosphorylation and apoptosis via GSK-3B signaling pathways ENSG00000137845 PMC9503744__F1 Crosstalk between Ca2+ Signaling and Cancer Stemness: The Link to Cisplatin Resistance ENSG00000132906 ENSG00000175054 ENSG00000164305 PMC2745643__F1 Beta-catenin signaling and its regulation ENSG00000134982 ENSG00000168036 PMC11551840__F6 Proposed modes of mechanism of action of AZD5582 in OSCC ENSG00000102871 ENSG00000285152 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000064012 PMC2939005__F1 Two major insulin signaling pathways PMC12114876__F2 Medicinal Chemistry Strategies in Targeting TGFBR1 Kinase Domain: Unveiling Insights into Inhibitor Structure–Activity Relationship (SAR) PMC6925247__F7 TIPRL potentiates survival of lung cancer by inducing autophagy through the eIF2Alpha-ATF4 pathway ENSG00000188554 ENSG00000128272 ENSG00000144895 ENSG00000143155 PMC2898064__F10 Views of predicted functional interactions ENSG00000026103 PMC3639655__F4 Schematic depiction of c-Myc functional interactions with other pathways (for full discussion, see section Induction–Reversion Tumorigenesis in Animal Models by Oncogene-Driven Cancer Network Formation) ENSG00000135446 ENSG00000136997 ENSG00000123374 ENSG00000105810 PMC8026474__F2 Simplified overview of PRR signalling pathways in gastrointestinal epithelial cells ENSG00000174125 ENSG00000239732 ENSG00000073331 ENSG00000167207 ENSG00000145365 ENSG00000187554 ENSG00000174885 ENSG00000091592 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000164342 PMC5037548__F4 Apoptosis signaling pathways induced by icariin and icariside II ENSG00000102871 ENSG00000168040 PMC6677617__F4 Shh activates the PI3K/AKT and INSM1 signaling pathways to stabilize and prevent N-myc from entering the proteasomal degradation pathway ENSG00000173404 ENSG00000164690 ENSG00000139352 PMC8397734__F4 Sulfur energy metabolism and physiological interaction scheme of E. rectale and B. wadsworthia in the human gut ENSG00000095059 ENSG00000155926 ENSG00000293532 PMC3533556__F7 IL-13–induced airway mucus production is attenuated by MAPK13 inhibition ENSG00000291363 ENSG00000016490 PMC5686390__F1 Mucosal-associated invariant T (MAIT) cell activation ENSG00000089692 ENSG00000134982 ENSG00000153029 ENSG00000281857 PMC2704469__F8 Scheme indicating expression of Tcf4 proteins and effects of Wnt–Beta-catenin signaling to inhibit the transition from premyelinating to mature oligodendrocyte ENSG00000184221 ENSG00000134982 ENSG00000134853 ENSG00000205927 ENSG00000196628 PMC8879721__F8 Ginsenoside Rh4 Suppressed Metastasis of Lung Adenocarcinoma via Inhibiting JAK2/STAT3 Signaling ENSG00000135446 ENSG00000170558 ENSG00000168610 PMC3233564__F3 Mammalian MAPK signaling pathways ENSG00000178573 ENSG00000127191 PMC6881749__F4 A proposed model of the impact of elevated levels of circulating IL-6 on skeletal muscle redox balance ENSG00000181019 ENSG00000196591 PMC6431020__F5 Schematic diagram of molecular mechanisms underlying PA-induced GC metastasis ENSG00000185591 PMC3097097__F2 Characterization of the myometrial transcriptome and biological pathways of spontaneous human labor at term ENSG00000112116 ENSG00000108688 ENSG00000185591 ENSG00000175104 ENSG00000163702 ENSG00000062485 PMC10970955__F1 Systematic engineering for the de novo biosynthesis of genistein and glycosylated derivatives ENSG00000169299 ENSG00000102977 ENSG00000026103 PMC9046764__F6 Genomic signatures of artificial selection in the Pacific oyster, Crassostrea gigas ENSG00000132906 ENSG00000110330 ENSG00000259207 ENSG00000070831 ENSG00000108861 ENSG00000134363 ENSG00000174804 ENSG00000011566 ENSG00000135446 ENSG00000134245 ENSG00000185269 ENSG00000064012 ENSG00000146648 PMC8642467__F4 Mutations that switch genes from two-hit to one-hit drivers in six cancer types ENSG00000149311 ENSG00000157764 ENSG00000148400 ENSG00000198793 ENSG00000121879 ENSG00000196712 ENSG00000079999 PMC8123811__F3 On Iron Metabolism and Its Regulation ENSG00000170365 ENSG00000010704 ENSG00000106327 ENSG00000105697 PMC8219471__F1 STING and liver disease ENSG00000164430 PMC9320502__F3 Reconnoitering the Therapeutic Role of Curcumin in Disease Prevention and Treatment: Lessons Learnt and Future Directions ENSG00000162711 ENSG00000178573 ENSG00000175104 PMC2880289__F6 Complex deregulation of the Neuregulin/ERBB2 signaling pathway ENSG00000090402 ENSG00000002330 ENSG00000163558 ENSG00000124882 ENSG00000198793 ENSG00000136997 ENSG00000108443 ENSG00000169032 ENSG00000100485 ENSG00000178568 PMC3494627__F3 Cancer-suppressive inflammation ENSG00000125538 ENSG00000172936 ENSG00000175104 PMC7463798__F3 Proposed signaling pathways affected by SphK inhibitors ENSG00000063176 ENSG00000198793 ENSG00000168036 PMC3728269__F1 Signaling pathways in melanoma.Notes: Oncoprotein Ras activates both the MAPK and PI3K/Akt survival pathways ENSG00000157764 ENSG00000168610 PMC4772274__F2 Ingenuity pathway analysis of miR-221 and miR-483 target genes ENSG00000100234 ENSG00000157404 ENSG00000095321 ENSG00000159388 ENSG00000064393 ENSG00000064218 ENSG00000141068 ENSG00000107669 ENSG00000161642 ENSG00000166068 ENSG00000073670 ENSG00000221823 ENSG00000007168 ENSG00000164742 ENSG00000102466 ENSG00000115415 ENSG00000102081 ENSG00000136997 ENSG00000162105 ENSG00000182389 PMC3910500__F6 Canonical PI3K and MAPK pathway activation determined by reverse phase protein arrays and compared between GBM subclasses: Proneural (P, purple, n=55) and Mesenchymal (M, red, n=45) ENSG00000169047 PMC3199248__F1 TLR induction of inflammation by parasitic infection ENSG00000172936 ENSG00000276561 PMC8985231__F8 Intercellular Communication in the Islet of Langerhans in Health and Disease ENSG00000116106 ENSG00000135333 ENSG00000180616 PMC5749594__F3B Association of the activity of metagene 19 with two distinct image phenotypes ENSG00000124102 ENSG00000144749 ENSG00000138798 ENSG00000146648 PMC9653095__F3 NAD+ synthesis from the de novo, Preiss-Handler and Salvage pathways ENSG00000278488 PMC5749594__F3A Association of the activity of metagene 19 with two distinct image phenotypes ENSG00000124102 ENSG00000144749 ENSG00000138798 ENSG00000146648 PMC9653095__F6 Graphic summary representation of tryptophan metabolism and disposition in cancer biology and proposed therapeutic strategies ENSG00000168003 ENSG00000103257 PMC3521040__F2 Molecular mechanisms of activation, amplification, regulation, and evasion of the AP C3 convertase ENSG00000196352 ENSG00000165280 ENSG00000006747 ENSG00000117335 PMC11800460__F7 Graphical abstract image illustrating the mechanism of EPN3-mediated EGFR stability and its role in NSCLC development ENSG00000138798 ENSG00000049283 ENSG00000146648 PMC3695632__F3 Case 19-2010: A 35-Year-Old Man with Adenocarcinoma of the Cecum ENSG00000002330 ENSG00000198793 ENSG00000136997 ENSG00000164327 ENSG00000146648 PMC8144931__F5 Next-generation sequencing analysis reveals that MTH-3, a novel curcuminoid derivative, suppresses the invasion of MDA-MB-231 triple-negative breast adenocarcinoma cells ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000069482 ENSG00000186716 ENSG00000197601 PMC3891682__F2 Putative miRNAs for the diagnosis of dyslexia, dyspraxia, and specific language impairment ENSG00000125266 ENSG00000099204 ENSG00000135622 ENSG00000135333 ENSG00000065320 ENSG00000137872 ENSG00000067900 ENSG00000184349 ENSG00000169242 ENSG00000182541 ENSG00000065135 ENSG00000196411 ENSG00000153993 ENSG00000092421 ENSG00000076356 ENSG00000137843 ENSG00000130669 ENSG00000198910 PMC5606116__F2 Signaling pathways of IL-2 ENSG00000198793 ENSG00000105639 PMC11837473__F1 Integrated stress response signaling pathway ENSG00000128272 PMC11837473__F3 Integrated stress response in neurodegenerative disorders ENSG00000111537 ENSG00000128272 ENSG00000101255 PMC10884763__F3 Illustrative representation of molecular mechanisms of obesity-induced non-communicable diseases PMC11837473__F2 Mitochondrial dysfunction and ISR: The activation of the integrated stress response (ISR) during mitochondrial dysfunction is triggered by various mechanisms ENSG00000128272 ENSG00000162600 ENSG00000081791 PMC8206782__F3 Cytokine Overproduction and Immune System Dysregulation in alloHSCT and COVID-19 Patients ENSG00000278718 ENSG00000124256 ENSG00000111537 ENSG00000130234 ENSG00000111837 ENSG00000198793 ENSG00000136869 ENSG00000276561 PMC10884763__F5 WATME-specific immunotherapy for obesity-induced coronary heart disease (CHD) ENSG00000162711 ENSG00000136869 ENSG00000169174 PMC12164274__F5 Mapping of transcriptomic data to the nonsmall cell lung cancer pathway ENSG00000132906 ENSG00000189283 ENSG00000019991 ENSG00000105639 ENSG00000122008 PMC7476772__F2 Immune Response to SARS-CoV2 & pharmacodynamics of rheumatology medications ENSG00000134982 ENSG00000168610 PMC4997642__F1 Canonical Wnt signaling pathway (reproduced with permission from) ENSG00000134982 ENSG00000168036 PMC9587158__F1 Emerging Therapies and Novel Targets for TDP-43 Proteinopathy in ALS/FTD ENSG00000104435 ENSG00000177971 PMC6804710__F1 Canonical and non-canonical Wnt signalling pathways known or needed to be proven to participate in rat tooth germ development.,,,,,,,,,,,,,,,,,,,, ENSG00000087095 ENSG00000100592 ENSG00000095739 ENSG00000100387 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000168036 ENSG00000196470 PMC9569894__F8 Transcriptome Analysis Reveals the Complex Regulatory Pathway of Background Color in Juvenile Plectropomus leopardus Skin Color Variation ENSG00000167941 ENSG00000169047 ENSG00000168036 ENSG00000080166 ENSG00000107165 PMC3294429__F4 The NDT80 transcriptional induction pathway PMC2804177__F9 The signaling pathways regulating osteoblast-like cells proliferation in response to OSS ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC5658232__F1 PI3K/Akt/mTor pathway and effects of mTOR-inhibitors ENSG00000140992 ENSG00000169047 PMC6335494__F7 Schematic model of intracellular signaling mechanisms regulating proteasome inhibitor-induced apoptosis by FLT3-ITD involving the STAT5/Pim axis and the mTORC1/eIF4F/Mcl-1 pathway PMC4240309__F2 Smad-dependent and Smad-independent TGFB family signaling ENSG00000070831 ENSG00000198793 ENSG00000175104 PMC7019324__F3 Pathways of macro-autophagy ENSG00000177169 ENSG00000152348 ENSG00000126775 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC7019324__F2 Extrinsic and intrinsic apoptotic pathway ENSG00000102871 ENSG00000168040 ENSG00000254550 PMC6077207__F8 Schematic presentation elucidating proposed mechanisms that TLB protects PC12 cells against oxidative stress-induced injury ENSG00000142082 ENSG00000079999 PMC5223235__F3 Processing and presentation of MHC class I and II restricted antigens for CD8+ and CD4+ T cell recognition, respectively ENSG00000134982 ENSG00000273686 PMC7019324__F7 Routes of the complement system with its inhibitors currently studied in kidney transplantation ENSG00000113600 ENSG00000244731 ENSG00000166278 ENSG00000182326 ENSG00000062485 ENSG00000236625 PMC7019324__F6 Toll-like receptor 4 signalling ENSG00000183735 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC11678759__F3 Signaling pathways of melatonin ENSG00000065833 ENSG00000144712 ENSG00000069956 PMC3470116__F6 Simplified schema of putative signaling pathways accountable for the differential responses of A549 (A) and SNB19 (B) cell lines to Hsp90 inhibition and IR ENSG00000135446 PMC3469673__F1 Activated CD47 is a proximate regulator of multiple cell survival and cell death pathways ENSG00000291971 ENSG00000145321 PMC6454043__F1 Ceramide (Cer) synthesis pathways and their cellular compartmentalization ENSG00000184381 ENSG00000100422 ENSG00000198793 ENSG00000292130 ENSG00000158828 ENSG00000069329 ENSG00000136869 ENSG00000135587 PMC6969104__F9 MUC1-C regulates lineage plasticity driving progression to neuroendocrine prostate cancer ENSG00000135446 ENSG00000173599 ENSG00000136997 PMC9001082__F3 PM2.5 Exposure and Asthma Development: The Key Role of Oxidative Stress ENSG00000198793 ENSG00000086991 PMC6318317__F1 Wnt signaling pathways and the intervention targets of Wnt pathway inhibitors ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC9001082__F4 PM2.5 Exposure and Asthma Development: The Key Role of Oxidative Stress ENSG00000198793 ENSG00000007171 ENSG00000106546 ENSG00000079999 PMC2748726__F1 Therapeutic targeting of the BCL6 oncogene for diffuse large B-cell lymphomas ENSG00000175054 ENSG00000137265 ENSG00000149554 ENSG00000124762 ENSG00000101425 PMC12069271__F5 Pathway diagram of the NF signaling pathway (available at https://www ENSG00000102871 ENSG00000163739 ENSG00000163734 ENSG00000164136 ENSG00000007908 ENSG00000131323 ENSG00000128342 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000164305 PMC6484783__F2 Histone chaperoning pathway: from ribosome to nucleosome ENSG00000292096 ENSG00000146872 ENSG00000143379 ENSG00000140326 ENSG00000198586 ENSG00000198700 PMC12069271__F4 Pathway diagram of lipid and atherosclerosis (available at https://www ENSG00000132906 ENSG00000162711 ENSG00000128272 ENSG00000002330 ENSG00000170458 ENSG00000172005 ENSG00000140287 ENSG00000007908 ENSG00000136869 ENSG00000150455 ENSG00000115718 ENSG00000168610 PMC4166933__F1 Multiple leptin signaling pathways ENSG00000168610 PMC2675987__F1 Calmodulin-dependent nuclear import and disease ENSG00000125398 ENSG00000132341 PMC10979123__F7 Schematic diagram illustrates the multifaceted role of the redox-sensitive GSK3B in podocyte injury upon type 2 diabetic insult and the protective effect of targeting GSK3B ENSG00000181019 ENSG00000169047 PMC3731217__F7 Cited1 Deficiency Suppresses Intestinal Tumorigenesis ENSG00000125931 ENSG00000134982 ENSG00000168036 PMC4066587__F2 The stomatal signaling pathway ENSG00000105722 ENSG00000110934 PMC7241242__F8 Metabolic pathway showing the reactions involved in drought stress response at day 13: Red and blue arrows represent active reactions in drought and control, respectively ENSG00000261701 ENSG00000122966 ENSG00000120438 ENSG00000062485 PMC8413067__F1 The Wound Healing through Noncoding RNA Interplay and GSK-3B/NFKB Signaling Interaction ENSG00000104365 ENSG00000107562 ENSG00000121966 PMC3564524__F10 Novel signaling pathways involved in apo(a)-mediated effects on vascular endothelial cells ENSG00000135218 ENSG00000291971 ENSG00000163914 ENSG00000168036 PMC3005738__F1 Metabolic pathway of tamoxifen ENSG00000196502 ENSG00000165841 ENSG00000197408 PMC4398509__F1 Working model for pathway for bacterial lipoic acid metabolism and its possible regulation ENSG00000107798 ENSG00000132693 PMC3606489__F3 TGFB/BMP and the Wnt pathway ENSG00000168036 PMC6664756__F4 Predicted mechanisms of ELF1 regulation of doxorubicin-induced apoptosis ENSG00000149311 ENSG00000139579 ENSG00000117408 ENSG00000100109 ENSG00000171791 ENSG00000180089 PMC8607587__F1 Multiocular organoids from human induced pluripotent stem cells displayed retinal, corneal, and retinal pigment epithelium lineages ENSG00000197713 PMC4526153__F4 The Biophysics and Cell Biology of Lipid Droplets ENSG00000173599 ENSG00000285482 ENSG00000198670 ENSG00000062282 PMC11312736__F7 Glycolysis/gluconeogenesis, pentose phosphate pathway, photosynthesis and sucrose and starch metabolism in zygotic embryos of Yucatan green dwarf and Mexican Pacific tall cultivars PMC10835843__F8 Expression heat map of related genes and metabolites in phenylpropane biosynthesis, ascorbic acid, succinic acid and glutamic acid metabolic pathway ENSG00000070444 ENSG00000104237 ENSG00000105953 ENSG00000115419 ENSG00000159399 ENSG00000062485 PMC11312736__F8 Saturated and unsaturated fatty acid metabolic pathways and mevalonate and isoprenoid biosynthesis at intermediate and mature stages of YGD and MPT zygotic embryos ENSG00000067064 ENSG00000113161 ENSG00000120437 ENSG00000167508 ENSG00000100294 PMC11542157__F2 Signaling pathways regulating CMA activity ENSG00000198793 ENSG00000112561 ENSG00000131095 PMC4850081__F23 Central Metabolism probed by hyperpolarized 13C enriched precursors ENSG00000172005 ENSG00000115419 PMC9258700__F4 Gynostemma pentaphyllum against non‐alcoholic fibre liver disease based on network pharmacology and molecular docking ENSG00000002330 ENSG00000026103 PMC9097439__F2 Regulatory role of short-chain fatty acids in inflammatory bowel disease ENSG00000162711 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC7904562__F5 Network of transcriptional NR1I3-mediated response elicited by pesticides (here shown: IMZ) in rat liver, as computed with Ingenuity Pathway Analysis software ENSG00000142192 ENSG00000197408 ENSG00000125686 ENSG00000140465 PMC11542157__F6 CMA dysfunction contributes to multiple diseases ENSG00000162711 ENSG00000138798 ENSG00000075891 ENSG00000146648 PMC11542157__F5 CMA and neurodegenerative diseases ENSG00000162711 ENSG00000112561 ENSG00000291761 PMC4905058__F2 General overview of the class I PI3K signaling pathway ENSG00000033327 ENSG00000002330 ENSG00000166278 ENSG00000010671 PMC4655250__F2 Endoplasmic reticulum stress-mediated pathways to both apoptosis and autophagy: Significance for melanoma treatment ENSG00000128272 ENSG00000157764 ENSG00000198793 ENSG00000162772 PMC8935059__F9 Mitochondria Related Cell Death Modalities and Disease ENSG00000104365 ENSG00000100906 ENSG00000109320 ENSG00000269335 ENSG00000173039 PMC8924541__F4 Antidiabetic Activity of Elephant Grass (Cenchrus Purpureus (Schumach.) Morrone) via Activation of PI3K/AkT Signaling Pathway, Oxidative Stress Inhibition, and Apoptosis in Wistar Rats ENSG00000042832 ENSG00000132646 ENSG00000171791 PMC8811214__F2 Cross-Talk Between EGFR and E-Cadherin ENSG00000087245 ENSG00000138798 ENSG00000168036 ENSG00000100985 ENSG00000168610 ENSG00000146648 PMC2911128__F1 PI3K/Akt/mTOR signaling pathway ENSG00000002330 ENSG00000198793 ENSG00000155792 PMC6895153__F5 Hormone-related pathways enriched in DEGs of the brain and gonads ENSG00000112964 ENSG00000138039 ENSG00000165409 ENSG00000113494 ENSG00000140416 PMC6406801__F6 Kinetochore PP2A-B56 and PP1 promote the stability of microtubule attachments and efficient Spindle Assembly Checkpoint silencing in animal cells ENSG00000137812 ENSG00000277909 ENSG00000143228 ENSG00000161888 ENSG00000166851 PMC5356307__F7 Model describing the effect of a synergy between extracellular TGFB1 and Hsp90B on downstream signalling in colon cancer cells ENSG00000105329 ENSG00000026103 PMC3911027__F4 Metabolic potential of Acidilobus-like populations from YNP deduced from coding sequences obtained from metagenome assemblies ENSG00000172005 ENSG00000168040 ENSG00000127948 PMC2384123__F8 Possible model for CCL5-mediated mRNA translation in CD4+ T cells ENSG00000198793 PMC3520613__F5 Macrophage VLDL Receptor Promotes PAFAH Secretion in Mother’s Milk and Suppresses Systemic Inflammation in Nursing Neonates ENSG00000146070 PMC8242269__F10 Large-scale Proteomic and Phosphoproteomic Analyses of Maize Seedling Leaves During De-etiolation ENSG00000197713 ENSG00000173599 PMC11775980__F2 Lipid Pathways Located at MAM ENSG00000100596 ENSG00000099194 ENSG00000075239 PMC8391210__F3 Follistatin-Like Proteins: Structure, Functions and Biomedical Importance ENSG00000150907 ENSG00000198793 PMC7602614__F3 STAT3 regulates the transcription of gene sets involved in cancer development ENSG00000275331 ENSG00000019991 ENSG00000122691 ENSG00000112715 ENSG00000168610 ENSG00000023839 PMC7602614__F2 JAK/STAT signaling drives the differentiation of T helper cells (Tregs) ENSG00000138378 ENSG00000115415 ENSG00000125538 ENSG00000107485 ENSG00000049768 ENSG00000168610 PMC5881442__F1 Mechanisms for visual chromophore production in the retina relevant to cone pigment regeneration ENSG00000180210 ENSG00000116745 ENSG00000197713 PMC3605242__F6 Ingenuity Pathway Analysis visualization of oncogene interactions ENSG00000167601 ENSG00000157404 ENSG00000111859 ENSG00000067369 ENSG00000183765 ENSG00000156475 ENSG00000100385 ENSG00000012048 ENSG00000180353 ENSG00000157500 ENSG00000239732 ENSG00000172216 ENSG00000272398 ENSG00000139687 ENSG00000140464 ENSG00000170027 ENSG00000105568 ENSG00000110395 ENSG00000118503 ENSG00000187554 ENSG00000172936 ENSG00000184216 ENSG00000146648 ENSG00000127616 ENSG00000141456 ENSG00000180182 ENSG00000135218 ENSG00000130522 ENSG00000276644 ENSG00000178209 ENSG00000150093 ENSG00000197442 ENSG00000117707 ENSG00000277273 ENSG00000164305 ENSG00000121966 ENSG00000010671 ENSG00000196586 ENSG00000175054 ENSG00000011422 ENSG00000051180 ENSG00000171105 ENSG00000259207 ENSG00000081237 ENSG00000065361 ENSG00000269335 ENSG00000168040 ENSG00000105639 ENSG00000168610 ENSG00000160691 ENSG00000149311 ENSG00000177606 ENSG00000114166 PMC9026097__F9 Transcriptomic Analysis of Fumarate Compounds Identifies Unique Effects of Isosorbide Di-(Methyl Fumarate) on NRF2, NF-kappaB and IRF1 Pathway Genes ENSG00000178573 ENSG00000196954 ENSG00000169429 ENSG00000125347 PMC6962519__F3 Mechanistic target of rapamycin (mTOR) complex 1 (mTORC1)-independent regulation of protein translation ENSG00000198793 ENSG00000155792 ENSG00000167658 PMC4051995__F2 Mammary Development and Breast Cancer: The Role of Stem Cells ENSG00000148400 ENSG00000074181 PMC11394644__F1 NAD+ biosynthesis pathways ENSG00000105835 ENSG00000162882 ENSG00000278488 ENSG00000183077 ENSG00000174611 PMC11394644__F3 Summary reaction schemes depicting the influence NAD+ biosynthesis pathway reactions on the tumor microenvironment (TME) ENSG00000105835 ENSG00000278488 ENSG00000157064 ENSG00000138617 PMC11394644__F2 Reaction schemes for NAD+-consuming enzymes ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000089163 ENSG00000283100 PMC6856900__F4 Gene expression profiles of the PI3K-AKT signaling pathway in treated HepG2 cell ENSG00000104812 ENSG00000002330 ENSG00000153094 ENSG00000169047 ENSG00000198793 ENSG00000115904 ENSG00000214827 ENSG00000141564 ENSG00000171791 ENSG00000169032 ENSG00000121879 ENSG00000103479 ENSG00000136997 ENSG00000118515 ENSG00000123374 ENSG00000136869 ENSG00000119535 ENSG00000109320 ENSG00000108342 ENSG00000213341 ENSG00000132356 ENSG00000160741 ENSG00000187840 ENSG00000151276 ENSG00000128272 ENSG00000040199 ENSG00000154188 PMC12084782__F7 Graphical abstract of this work PMC8989389__F1 Malignant glioma subset from actuate 1801: Phase I/II study of 9-ING-41, GSK-3B inhibitor, monotherapy or combined with chemotherapy for refractory malignancies ENSG00000171791 PMC8940245__F3 Akt: A Potential Drug Target for Metabolic Syndrome ENSG00000042832 ENSG00000144857 ENSG00000150907 ENSG00000169047 PMC11754404__F7 The effect of Formononetin (FMN) on porcine oocyte in vitro maturation and early embryo in vitro ENSG00000173992 ENSG00000095303 ENSG00000026508 ENSG00000073756 ENSG00000079999 PMC8597313__F2 New perspectives on cytoskeletal dysregulation and mitochondrial mislocalization in amyotrophic lateral sclerosis ENSG00000104435 ENSG00000277586 ENSG00000164430 ENSG00000123240 ENSG00000100285 ENSG00000148798 ENSG00000158828 ENSG00000123143 ENSG00000164305 PMC10299206__F2 TGFB signaling pathway ENSG00000137834 ENSG00000198793 ENSG00000163914 ENSG00000177606 ENSG00000113360 ENSG00000076604 PMC10299206__F3 Relationship between genes related to TGFB signaling pathway and pathogenesis of oral cancers ENSG00000135446 ENSG00000136997 ENSG00000020633 ENSG00000118520 ENSG00000175104 PMC3601079__F3 Maslinic Acid-Enriched Diet Decreases Intestinal Tumorigenesis in ApcMin/+ Mice through Transcriptomic and Metabolomic Reprogramming ENSG00000132906 ENSG00000002330 ENSG00000134982 ENSG00000177606 ENSG00000168036 ENSG00000164305 PMC5706558__F1 Strategy for analysis of ERBB2-driven gastric cancer ENSG00000136997 ENSG00000146648 PMC10384322__F2 Free Radical and Viral Infection: A Review from the Perspective of Ferroptosis ENSG00000167468 ENSG00000136869 ENSG00000047936 ENSG00000167419 PMC5006950__F1 PD and PK pathways of HMGCo A reductase inhibitors (Statins) ENSG00000113161 PMC5706558__F8 Summation of the proteomic values for the ERBB2− sample set for genes present in the regulation of actin cytoskeleton pathway for ERBB2− set from KEGG ENSG00000180210 ENSG00000197721 ENSG00000134982 ENSG00000163914 ENSG00000089159 PMC2727866__F1 EGFR-dependent MAPK activation ENSG00000113070 ENSG00000198670 ENSG00000146648 ENSG00000140443 PMC5706558__F7 ERBB signaling pathway analysis ENSG00000169291 ENSG00000163235 PMC4733034__F2 Assay for defining the immunostimulatory potential of different RNAs ENSG00000213928 ENSG00000276561 PMC9637655__F1 Dual role of the hexosamine biosynthetic pathway in cardiac physiology and pathophysiology ENSG00000198408 ENSG00000100219 PMC5750051__F3 Proposed pathway for B12 targeting to methionine synthase for MeCbl synthesis ENSG00000168288 ENSG00000132763 PMC7600793__F6 Scheme of N9 microglia NF-kB, NFAT, MAPK, and IL-10/STAT3 inflammatory pathways modulated by 2J19 GIB fraction ENSG00000168610 PMC3406917__F3 Schematic Diagram of Matrix Protein Import into Peroxisomes.Cytosolic PEX5 and PEX7 recognize their cargo proteins (square and round shapes) via binding of specific targeting sequences, PTS1 and PTS2, respectively ENSG00000124587 ENSG00000288217 PMC9637655__F3 Dual role of the hexosamine biosynthetic pathway in cardiac physiology and pathophysiology ENSG00000084093 ENSG00000135218 ENSG00000198793 ENSG00000086991 ENSG00000100219 ENSG00000099940 PMC5112273__F2 How autism-risk genes regulate neuronal structure and their sites of action ENSG00000157540 ENSG00000197283 ENSG00000198793 ENSG00000041515 ENSG00000198010 ENSG00000154654 ENSG00000164506 ENSG00000292254 PMC5736463__F7 RUNX2-I is an early regulator of epithelial-mesenchymal cell transition in the chick embryo ENSG00000169554 ENSG00000124216 ENSG00000133110 ENSG00000122691 ENSG00000019549 PMC5406241__F1 Schematic illustrating our strategy to generate iPSCs resistant to IL-1-mediated signaling for tissue engineering applications ENSG00000102871 ENSG00000132478 ENSG00000172936 PMC3959765__F3 RANKL-perturbed network and master regulators ENSG00000033327 ENSG00000070831 ENSG00000105329 ENSG00000291971 ENSG00000170558 ENSG00000087586 ENSG00000150093 ENSG00000135341 ENSG00000112715 ENSG00000196628 ENSG00000125398 ENSG00000122691 ENSG00000038427 ENSG00000136997 ENSG00000125968 ENSG00000155090 ENSG00000133895 ENSG00000141448 ENSG00000173039 ENSG00000006062 ENSG00000277641 ENSG00000132170 ENSG00000117020 ENSG00000110395 ENSG00000131323 ENSG00000175104 ENSG00000150630 PMC4189458__F2 Progesterone functions via intrinsic (mitochondria-centered) and extrinsic (cell membrane-mediated) pathway of apoptosis ENSG00000168040 ENSG00000026103 PMC4459083__F1 Scheme for producing fatty acid-derived biofuels in yeast ENSG00000171759 ENSG00000026103 PMC3475164__F1 Biosynthesis of glycerophospholipids ENSG00000173599 ENSG00000171759 ENSG00000133027 PMC7798998__F2 Innate immune signaling pathways sensing SARS-CoV-2 ENSG00000164430 ENSG00000088888 ENSG00000172936 ENSG00000164342 PMC1564158__F2 Predicting Essential Components of Signal Transduction Networks: A Dynamic Model of Guard Cell Abscisic Acid Signaling ENSG00000173599 ENSG00000145321 PMC2709272__F1 Wnt/Beta-catenin signaling in adipogenesis and metabolism ENSG00000120057 ENSG00000169884 ENSG00000111186 PMC7989008__F5 Re-analysis of 29 selected genes by KEGG pathway enrichment ENSG00000184990 ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000275679 ENSG00000142192 ENSG00000182511 ENSG00000112378 ENSG00000105810 ENSG00000164305 PMC10377129__F9 Active Estrogen–Succinate Metabolism Promotes Heme Accumulation and Increases the Proliferative and Invasive Potential of Endometrial Cancer Cells ENSG00000144659 ENSG00000084676 ENSG00000117118 PMC9500712__F8 Molecular Mechanisms of Cassia fistula against Epithelial Ovarian Cancer Using Network Pharmacology and Molecular Docking Approaches ENSG00000157404 ENSG00000181104 ENSG00000168036 ENSG00000087586 ENSG00000171791 ENSG00000121879 ENSG00000179295 ENSG00000163631 ENSG00000126218 ENSG00000150782 ENSG00000169291 ENSG00000082175 ENSG00000149968 ENSG00000128052 ENSG00000123374 ENSG00000131473 ENSG00000087245 ENSG00000171105 ENSG00000131747 ENSG00000173039 ENSG00000073756 ENSG00000274247 ENSG00000164362 ENSG00000100985 ENSG00000005381 PMC7258299__F3 Metabolic pathways that produce and interconvert acyl-CoAs involved in histone acylations ENSG00000131473 ENSG00000153046 ENSG00000105607 PMC7510089__F5 Key genes analysis in the AD ENSG00000157404 ENSG00000142627 ENSG00000107562 ENSG00000091879 ENSG00000112715 ENSG00000168610 ENSG00000132170 ENSG00000145431 ENSG00000107263 ENSG00000170962 ENSG00000049130 ENSG00000177606 ENSG00000136997 ENSG00000140285 ENSG00000026508 ENSG00000169429 ENSG00000154188 ENSG00000227345 ENSG00000150630 PMC8290582__F3 Alpha- and Beta-adrenergic signaling in phenotypic targeting: significance in benign and malignant urologic disease ENSG00000002330 ENSG00000177606 PMC7510089__F4 Key gene analysis in the OS ENSG00000087245 ENSG00000284832 ENSG00000107562 ENSG00000143878 ENSG00000162551 ENSG00000169047 ENSG00000099860 ENSG00000087586 ENSG00000116717 ENSG00000168610 ENSG00000132170 ENSG00000245848 ENSG00000134057 ENSG00000177606 ENSG00000118515 ENSG00000026508 ENSG00000142731 ENSG00000146648 ENSG00000139112 ENSG00000150630 PMC7500440__F1 Pro-tumour activities of neutrophils.a) Neutrophils can express ligands of immune checkpoints expressed on T cells, such as PD-L1 ENSG00000163464 ENSG00000138798 ENSG00000169047 ENSG00000118520 ENSG00000100985 PMC6770430__F2 Hyperglycemia associated metabolic reprogramming in cancer cells and potential targets ENSG00000042832 ENSG00000078237 PMC8313570__F1 Regulatory pathways of ferroptosis ENSG00000167468 ENSG00000127948 ENSG00000115419 PMC5835589__F1 Targeting DDR vulnerabilities of SCLC ENSG00000149311 ENSG00000175054 ENSG00000136997 ENSG00000123374 ENSG00000101224 ENSG00000139687 PMC545806__F7 Different pathways use the RecQ helicase in response to replication stalling ENSG00000260314 ENSG00000051180 PMC9099610__F2 Poultry Meat and Eggs as an Alternative Source of n-3 Long-Chain Polyunsaturated Fatty Acids for Human Nutrition ENSG00000197977 PMC6763782__F3 Regulation of the main phases of the autophagic pathway by the C2‐WW‐HECT E3s ENSG00000177169 ENSG00000123395 ENSG00000198382 ENSG00000150991 ENSG00000123124 PMC10253478__F1 Action of probiotics ENSG00000174123 ENSG00000184956 ENSG00000145321 ENSG00000113520 ENSG00000049768 ENSG00000117983 ENSG00000145113 ENSG00000173702 ENSG00000293532 PMC4404113__F5 Unigenes involved in the three metabolic pathways ENSG00000186063 ENSG00000119125 PMC8008218__F6 Study findings ENSG00000170558 PMC9561884__F4 Roles and targeting options of TRIM family proteins in tumor ENSG00000166326 ENSG00000163462 ENSG00000151657 ENSG00000105298 ENSG00000015285 ENSG00000119283 ENSG00000183718 ENSG00000174611 PMC5614325__F2 SASP regulation ENSG00000149311 ENSG00000141867 ENSG00000148400 ENSG00000198793 PMC9561884__F5 Roles and targeting options of TRIM family proteins in tumor ENSG00000154370 ENSG00000213186 ENSG00000166326 ENSG00000119401 ENSG00000198793 ENSG00000168036 ENSG00000132481 ENSG00000134253 ENSG00000166436 ENSG00000168610 PMC4771746__F2 Example pathway (Alzheimer's disease) overlaid with gene expression data from BBB cell line ENSG00000132906 ENSG00000196296 ENSG00000142192 ENSG00000002330 ENSG00000073578 ENSG00000168040 ENSG00000137845 ENSG00000164305 ENSG00000178607 ENSG00000196549 ENSG00000198838 ENSG00000125538 ENSG00000120868 ENSG00000119912 ENSG00000064012 ENSG00000026103 PMC11808201__F2 Mass Spectrometry as a First-Line Diagnostic Aid for Congenital Disorders of Glycosylation ENSG00000000419 ENSG00000136152 ENSG00000164414 ENSG00000134851 ENSG00000153989 ENSG00000134910 ENSG00000120697 ENSG00000117682 ENSG00000136710 ENSG00000244045 ENSG00000128039 ENSG00000160131 ENSG00000213380 ENSG00000168538 ENSG00000138821 ENSG00000173540 ENSG00000114850 ENSG00000198856 ENSG00000166685 ENSG00000168282 ENSG00000185344 ENSG00000102158 ENSG00000157353 ENSG00000180879 ENSG00000163933 ENSG00000182220 ENSG00000214160 ENSG00000136908 ENSG00000177239 ENSG00000292209 ENSG00000089597 ENSG00000101901 ENSG00000126091 ENSG00000104723 ENSG00000244038 ENSG00000139133 ENSG00000163527 ENSG00000088035 ENSG00000117620 ENSG00000164597 ENSG00000130175 PMC12212355__F2 Preventing T cell exhaustion and enhancing cytotoxicity through metabolic reprogramming ENSG00000291603 ENSG00000156127 ENSG00000155903 ENSG00000096717 ENSG00000115523 PMC2043390__F9 Biphasic expression and up-regulation of HWP1 at the bud-hypha transition ENSG00000070831 PMC6037732__F8 Cell cycle arrest and apoptosis of hepatocytes ENSG00000078304 PMC3059259__F2 Autophagy, inflammation and neurodegenerative disease ENSG00000111537 ENSG00000125538 PMC3367549__F4 BMP signaling pathway and regulation of SMAD activity ENSG00000170365 ENSG00000137834 PMC3367549__F3 Sonic hedgehog (SHH) signaling pathway ENSG00000125820 ENSG00000180447 ENSG00000106571 ENSG00000112210 ENSG00000144857 ENSG00000166813 ENSG00000164690 ENSG00000128602 PMC8576332__F7 Suppression of EGFR/PKCD/NFKB Signaling Associated With Imipramine-Inhibited Progression of Non-Small Cell Lung Cancer ENSG00000138798 ENSG00000100985 ENSG00000168040 ENSG00000146648 ENSG00000026103 PMC5770391__F4 Changes in brain energy metabolism during worker maturation elucidated by pathway analysis of data from brain RNA-seq experiments ENSG00000131473 ENSG00000173599 ENSG00000105953 ENSG00000062485 PMC7885061__F2 Altered gene expression profiles and signaling pathways in vitiligo ENSG00000108443 ENSG00000080166 ENSG00000171791 ENSG00000107165 ENSG00000049768 PMC8211512__F2 Mitochondrial Quality Control in Cardiac Ischemia/Reperfusion Injury ENSG00000116688 PMC3864900__F6 Ubiquitylation in immune defence and pathogen evasion ENSG00000078747 ENSG00000175104 PMC3428099__F1 FAM83A and FAM83B: candidate oncogenes and TKI resistance mediators ENSG00000002330 ENSG00000157764 ENSG00000138798 ENSG00000198793 ENSG00000136997 ENSG00000168143 ENSG00000146648 ENSG00000147689 PMC3864900__F3 Ubiquitylation in immune defence and pathogen evasion ENSG00000183735 ENSG00000167207 ENSG00000197530 ENSG00000113595 ENSG00000169871 ENSG00000121060 ENSG00000101752 PMC9018712__F10 Compound mutant phenotypes of Vangl2, Grhl3, Usp39, and Ube1 genes during mouse development and schematic model of USP39/GRHL3 complex in the de-ubiquitination pathway ENSG00000158055 PMC5562757__F9 Mechanistic model for ATF3-mediated negative regulation of antiviral and autophagy pathways in the absence of type I IFN ENSG00000213928 ENSG00000187608 ENSG00000115415 ENSG00000162772 ENSG00000057663 PMC8888345__F2 Adaptive chromatin remodeling and transcriptional changes of the functional kinome in tumor cells in response to targeted kinase inhibition ENSG00000291971 ENSG00000198793 ENSG00000136997 ENSG00000008086 ENSG00000129514 ENSG00000111816 ENSG00000146648 PMC3367549__F2 Canonical (left) and noncanonical (right) WNT signaling pathways ENSG00000281324 ENSG00000162337 ENSG00000100592 ENSG00000163914 ENSG00000177606 ENSG00000168036 PMC3367549__F1 FGF signaling cascades, an example of RTK signaling ENSG00000002330 ENSG00000070831 ENSG00000244405 ENSG00000163914 ENSG00000175832 ENSG00000177606 PMC11202107__F1 Suppressor of Cytokine Signaling Proteins 3 and 5 Potentially Delineate Polarization of Th cells in Chronic Rhinosinusitis ENSG00000138378 ENSG00000105397 ENSG00000171150 ENSG00000107485 ENSG00000105639 ENSG00000168610 PMC7409382__F1 S1PRs signaling regulating endothelial barrier function ENSG00000163914 ENSG00000213694 ENSG00000267534 ENSG00000183018 PMC2983445__F3 Growth factor signaling pathways mediating survival in multipotential stromal cells ENSG00000019991 ENSG00000002330 ENSG00000138798 ENSG00000150907 ENSG00000171791 ENSG00000146648 PMC2983445__F2 Growth factor signaling pathways mediating proliferation in multipotential stromal cells ENSG00000154342 ENSG00000019991 ENSG00000134982 ENSG00000138798 ENSG00000168036 ENSG00000146648 PMC6273666__F6 The possible inhibitory mechanism of ethyl acetate fraction of M ENSG00000125538 ENSG00000136869 PMC9502517__F2 Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach ENSG00000168040 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC8591777__F5 Application of Lipidomics for Assessing Tissue Lipid Profiles of Patients With Squamous Cell Carcinoma ENSG00000173599 ENSG00000163064 ENSG00000154059 ENSG00000164778 PMC3467044__F9 Model depicting the molecular underpinnings of lamin B2 origin licensing ENSG00000151376 ENSG00000094804 ENSG00000167513 ENSG00000136997 ENSG00000115942 ENSG00000139372 PMC3678724__F1 Alterations of the AKT pathway in human cancer ENSG00000134086 ENSG00000002330 ENSG00000025293 ENSG00000196712 PMC6056347__F3 The complex interplay between ER stress and liver damage and transformation(1) Unremediable ER stress in hepatocytes can elicit cell death, which might proceed through apoptotic, necrotic, or pyroptotic pathways or a combination thereof ENSG00000162711 ENSG00000164305 PMC10556370__F3 Mechanisms underlying TAX-mediated neuroprotection against AD or CAA ENSG00000142192 ENSG00000096717 PMC6716635__F3 Sequential analysis of myocardial gene expression with phenotypic change: Use of cross-platform concordance to strengthen biologic relevance ENSG00000123700 ENSG00000159200 ENSG00000135547 ENSG00000130234 ENSG00000113296 ENSG00000160808 ENSG00000120937 PMC3292500__F3 Top scored pathway map affected by BaP "Apoptosis and survival_Endoplasmic reticulum stress response" ENSG00000128272 PMC4732899__F6 Epidermal growth factor receptor signaling regulates granulocyte-macrophage colony-stimulating factor production by airway epithelial cells and established allergic airway disease ENSG00000109321 ENSG00000134982 ENSG00000113520 ENSG00000112115 ENSG00000146648 PMC9320762__F4 Non-Canonical Programmed Cell Death in Colon Cancer ENSG00000137275 ENSG00000136869 ENSG00000168040 ENSG00000168404 ENSG00000285379 ENSG00000164342 PMC9320762__F2 Non-Canonical Programmed Cell Death in Colon Cancer ENSG00000167468 ENSG00000072274 ENSG00000136381 PMC9320762__F1 Non-Canonical Programmed Cell Death in Colon Cancer ENSG00000149311 ENSG00000175054 ENSG00000123374 ENSG00000138385 PMC11011199__F2 Prediction of Response to Anti-Angiogenic Treatment for Advanced Colorectal Cancer Patients: From Biological Factors to Functional Imaging ENSG00000002330 ENSG00000291971 PMC5626732__F8 Signalling disruptions in Depdc5 FS/FS mice ENSG00000100150 ENSG00000114388 ENSG00000169047 PMC2700035__F6 Load-driven signaling pathways predicted with ankle loading at 1 h after the last loading ENSG00000262634 ENSG00000136457 ENSG00000134982 ENSG00000147869 ENSG00000229894 ENSG00000134363 ENSG00000168036 ENSG00000115718 ENSG00000139687 PMC6295338__F3 TPS EGF Response Pathway Model ENSG00000173821 ENSG00000105722 ENSG00000029363 ENSG00000204842 ENSG00000128512 ENSG00000102606 ENSG00000138798 ENSG00000050748 ENSG00000171475 ENSG00000101266 ENSG00000169032 ENSG00000099942 ENSG00000159216 ENSG00000149269 ENSG00000165458 ENSG00000198087 ENSG00000076641 ENSG00000072135 ENSG00000124181 ENSG00000161542 ENSG00000163399 ENSG00000142627 ENSG00000106299 ENSG00000167552 ENSG00000160691 ENSG00000063245 ENSG00000110395 ENSG00000164056 ENSG00000133124 ENSG00000100348 ENSG00000141198 ENSG00000146648 PMC3442837__F1 Regulation of phenotypic transitions in the fungal pathogen Candida albicans ENSG00000196511 ENSG00000070831 PMC1852792__F6 A hypothetical model for association of four subcomplexes in the FA core complex ENSG00000131944 ENSG00000077152 PMC3169732__F6 Schematic diagram illustrating the proposed signaling pathway involved in cigarette smoke extract-induced increase in expressions of inflammatory genes in airway smooth muscle cells ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC5627668__F1 N-Arachidonoyl Dopamine: A Novel Endocannabinoid and Endovanilloid with Widespread Physiological and Pharmacological Activities ENSG00000117480 ENSG00000196689 PMC8810792__F7 Transcriptome of human neuroblastoma SH-SY5Y cells in response to 2B protein of enterovirus-A71 ENSG00000023445 ENSG00000104856 ENSG00000108691 ENSG00000049249 ENSG00000148344 ENSG00000104368 PMC8822417__F8 Activation of PPARG in bladder cancer via introduction of the long arm of human chromosome 9 ENSG00000129514 ENSG00000107485 ENSG00000132170 PMC12199311__F7 Efficient Generation of Megakaryocyte Progenitors and Platelets From HSPCs via JAK2/STAT3 Signaling ENSG00000179111 ENSG00000168610 PMC6761106__F2 Suggestive model for receptor-mediated pathway involved in CD biology ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000128602 ENSG00000237834 PMC7801250__F3 Synopsis of lysine monomethylation events involved in photosynthesis and carbon metabolism in SynechocystisA ENSG00000182511 ENSG00000117118 PMC6226306__F1 New Therapies in Head and Neck Cancer ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC8076159__F6 Novel circGFRA1 Promotes Self-Renewal of Female Germline Stem Cells Mediated by m6A Writer METTL14 ENSG00000145388 ENSG00000187871 PMC7063815__F1 Relationship between mTOR and tumors ENSG00000188486 ENSG00000264522 ENSG00000163961 ENSG00000198793 ENSG00000155792 ENSG00000127191 PMC8994166__F5 Defining the Role of Mitochondrial Fission in Corneal Myofibroblast Differentiation ENSG00000116688 ENSG00000171109 PMC7876650__F2 Contrast effects of autophagy in the treatment of bladder cancer ENSG00000177169 ENSG00000123395 ENSG00000083290 ENSG00000112561 ENSG00000189298 PMC4601263__F5 CLN3 and sphingolipid signaling pathway interactions analyzed using Pathway Studio ENSG00000261832 ENSG00000172292 ENSG00000174607 ENSG00000168350 ENSG00000143418 PMC9354743__F2 RNA m6A modification orchestrates the rhythm of immune cell development from hematopoietic stem cells to T and B cells ENSG00000145388 ENSG00000198492 ENSG00000165819 PMC7758733__F7 Proposed signal transduction pathways by which quercetin induces apoptosis in AML cells ENSG00000198793 ENSG00000171791 PMC6838415__F8 Gut microbiota from colorectal cancer patients enhanced the progression of intestinal adenoma in Apcmin/+ mice ENSG00000162711 ENSG00000134982 ENSG00000125538 ENSG00000168036 PMC7437582__F1 New insights into Wnt signaling alterations in amyotrophic lateral sclerosis: a potential therapeutic target? ENSG00000134982 ENSG00000112655 ENSG00000168036 PMC5039377__F4 DNA-damage response pathway-network ENSG00000149311 ENSG00000175054 ENSG00000134574 ENSG00000104320 ENSG00000132646 ENSG00000136997 ENSG00000132383 ENSG00000095002 ENSG00000123268 ENSG00000136936 PMC8847669__F1 Multi-Level Computational Modeling of Anti-Cancer Dendritic Cell Vaccination Utilized to Select Molecular Targets for Therapy Optimization ENSG00000169429 ENSG00000127191 PMC11619685__F4 Activation of the p38 MAPK-mediated senescence pathway can occur because of pH changes or stimulation of ASIC1 or ASIC3, which initiates the ATM/ATR pathway ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 ENSG00000096717 PMC8009543__F1 NLRP3 activation ENSG00000162711 ENSG00000088888 ENSG00000116688 ENSG00000125538 ENSG00000172936 ENSG00000265972 PMC5650369__F8 Fasting inhibits colorectal cancer growth by reducing M2 polarization of tumor-associated macrophages ENSG00000168610 ENSG00000057663 PMC3169577__F1 Evolution of the TGFB Signaling Pathway and Its Potential Role in the Ctenophore, Mnemiopsis leidyi ENSG00000170365 ENSG00000137834 PMC8603464__F1 Regulatory role of the transforming growth factorB signaling pathway in the drug resistance of gastrointestinal cancers ENSG00000178860 ENSG00000170558 ENSG00000019549 ENSG00000272398 ENSG00000121966 PMC11619685__F2 Exploration and breakthrough in the mode of intervertebral disc cell death may lead to significant advances in treatments for intervertebral disc degeneration ENSG00000278718 ENSG00000162711 PMC10669584__F1 APE1/Ref-1 role in inflammatory bowel disease and the potential of redox signaling inhibition ENSG00000136869 ENSG00000168610 PMC11619685__F1 Exploration and breakthrough in the mode of intervertebral disc cell death may lead to significant advances in treatments for intervertebral disc degeneration ENSG00000002330 ENSG00000140379 ENSG00000168040 PMC7167255__F7 STYX/FBXW7 axis participates in the development of endometrial cancer cell via Notch–mTOR signaling pathway ENSG00000198252 ENSG00000198793 ENSG00000109670 PMC2819730__F1 Urine-based assays for the detection of bladder cancer ENSG00000164161 ENSG00000078369 ENSG00000044115 ENSG00000157193 ENSG00000159461 ENSG00000072274 ENSG00000162772 ENSG00000119004 PMC9456256__F2 Metabolic and Cellular Compartments of Acetyl-CoA in the Healthy and Diseased Brain ENSG00000131473 ENSG00000079432 ENSG00000062485 ENSG00000026103 PMC2948663__F1 Molecular and genetic events in mammalian sex determination and differentiation ENSG00000162552 ENSG00000169218 ENSG00000104899 ENSG00000143355 ENSG00000173894 ENSG00000170370 ENSG00000125398 ENSG00000137090 ENSG00000285109 ENSG00000139549 ENSG00000102678 PMC2675653__F1 CART analysis of NER pathway and esophageal cancer risk ENSG00000012061 ENSG00000136936 PMC6952788__F6 Cartoon illustrating the role of RAC1B in negative regulation of the epithelial-mesenchymal transition (EMT) program in (pancreatic) epithelial cells ENSG00000124216 ENSG00000105329 PMC4389820__F1 Major interconnected signaling pathways that regulate EMT ENSG00000170558 ENSG00000168036 ENSG00000175104 ENSG00000128602 PMC3458820__F8 Acute Erythemal Ultraviolet Radiation Causes Systemic Immunosuppression in the Absence of Increased 25-Hydroxyvitamin D3 Levels in Male Mice ENSG00000111012 ENSG00000019186 ENSG00000186104 PMC4926486__F12 Mechanism of cell death in murine lung epithelial cells after repeated cycles of hyperoxia, radiation, and double-hit combination challenge ENSG00000171791 ENSG00000164305 PMC8895238__F1 Hypoxia in the Interferon Response ENSG00000183735 ENSG00000213928 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000163565 ENSG00000160710 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC6672053__F4 Cellular response to T–R conflicts ENSG00000012048 ENSG00000175054 ENSG00000144554 ENSG00000187790 ENSG00000139618 PMC3572003__F1 Altered energy metabolism in cancer ENSG00000136997 PMC8754411__F8 Schematic drawing showing that MSC-exo eye drops alleviate GVHD-associated dry eye disease by reprogramming M1 macrophages to M2 via miR-204–mediated targeting of IL-6R/Stat3 pathway ENSG00000110651 ENSG00000010278 ENSG00000135404 ENSG00000118520 ENSG00000168610 PMC8841219__F2 The renin-angiotensin system in NETosis in the coronavirus disease 2019 (COVID-19) ENSG00000130234 ENSG00000137509 PMC9035226__F6 Summary & conceptualized pathway ENSG00000163739 ENSG00000198742 ENSG00000125968 ENSG00000284984 PMC1538848__F3 Expression data analysis and visualization on the PANTHER website ENSG00000213658 ENSG00000119912 PMC7577645__F2 TNFA and Reactive Oxygen Signaling in Vascular Smooth Muscle Cells in Hypertension and Atherosclerosis ENSG00000102189 ENSG00000102871 ENSG00000127191 ENSG00000188747 PMC6591147__F3 Mechanisms promoting regulatory T cell (Treg) development and immunosuppression in the tumor microenvironment ENSG00000102962 ENSG00000123374 ENSG00000049768 PMC7885861__F1 Expression and function of the insulin/insulin-like growth factor system in glioblastoma cells ENSG00000171105 ENSG00000115457 ENSG00000169047 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC6444363__F6 Tat promotes astrogliogenesis over neurogenesis through its binding to Notch to activate the Notch signaling pathway ENSG00000168214 ENSG00000273529 ENSG00000114315 PMC12211004__F7 Schematic diagram regarding key parts of this study ENSG00000145623 ENSG00000099985 PMC7138577__F7 Proposed model of the combinatorial effect of DDP and melatonin on NPC cells ENSG00000125398 ENSG00000134982 ENSG00000026508 ENSG00000168036 ENSG00000118971 ENSG00000125084 PMC9496650__F2 Inhibition and potential treatment of colorectal cancer by natural compounds via various signaling pathways ENSG00000134982 ENSG00000168036 PMC10987652__F7 GSK3B inhibition inhibits microtubule dynamics ENSG00000071246 ENSG00000114999 ENSG00000177868 PMC10239817__F1 Peptides in reversing chemoresistance of breast cancer: current facts and future prospects PMC2772826__F1 Apoptosis in animal models of virus-induced disease ENSG00000168040 PMC7722149__F1 Topical L-thyroxine: The Cinderella among hormones waiting to dance on the floor of dermatological therapy? ENSG00000198793 PMC10375937__F13 Cardioprotective effects of arjunolic acid in LPS-stimulated H9C2 and C2C12 myotubes via the My88-dependent TLR4 signaling pathway ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC11890417__F8 The role of LINC01305 and LAD1 in ESCC ENSG00000159166 ENSG00000170558 PMC3606520__F6 Summary of the putative biosynthetic pathway of non-arthro and arthro-series neutral GSLs in the cyst of the brine shrimp ENSG00000147869 PMC3155178__F1 Synthesis of Dihydrotestosterone via the Classic and Alternative (Backdoor) PathwaysThe classic pathway of steroidogenesis leading to dihydrotestosterone is shown on the left, and the alternative pathway is shown on the right ENSG00000086696 ENSG00000151632 ENSG00000203859 ENSG00000127948 PMC2546909__F1 Signal transduction pathway elicited by Env interaction with CCR5 required for Rac-1 activation and membrane fusion ENSG00000042832 ENSG00000156299 PMC10887283__F2 Therapeutic potential of anti-IL-1 agents in hidradenitis suppurativa ENSG00000115008 ENSG00000081041 ENSG00000163739 ENSG00000136696 ENSG00000136694 ENSG00000125538 ENSG00000134070 ENSG00000169429 ENSG00000172936 ENSG00000112149 ENSG00000184216 ENSG00000115009 ENSG00000115594 PMC5564228__F2 Genomics, Biology, and Human Illness: Advances in the Monogenic Autoinflammatory Diseases ENSG00000183735 ENSG00000213928 ENSG00000164430 ENSG00000105397 ENSG00000115415 PMC7727076__F6 p53 signal pathway and cell cycle pathway regulated by CDK1 and CCNA2 in pancreatic adenocarcinoma (PAAD) ENSG00000132906 ENSG00000196470 ENSG00000164305 ENSG00000276876 ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000132646 ENSG00000042286 ENSG00000123374 ENSG00000112378 ENSG00000140743 PMC3540985__F1 CYTOKINES, INFLAMMATION AND COLON CANCER ENSG00000173039 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC10375937__F14 Cardioprotective effects of arjunolic acid in LPS-stimulated H9C2 and C2C12 myotubes via the My88-dependent TLR4 signaling pathway ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC8023278__F10 Estrogen signaling pathway ranked first in Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment terms ENSG00000082175 ENSG00000163235 ENSG00000160182 ENSG00000147654 ENSG00000171345 PMC8079281__F8 TGF-Beta-induced cell motility requires downregulation of ARHGAPs to sustain Rac1 activity ENSG00000138639 ENSG00000160293 ENSG00000141968 PMC8023278__F11 Osteoclast differentiation signaling pathway ranked twenty-first in Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment terms ENSG00000120833 ENSG00000170909 ENSG00000213928 ENSG00000101307 ENSG00000163235 ENSG00000291971 ENSG00000073910 ENSG00000083799 ENSG00000010671 ENSG00000143387 PMC6289038__F2 Protein–protein network and pathway analysis ENSG00000110330 ENSG00000105327 ENSG00000164327 ENSG00000171791 ENSG00000170890 ENSG00000134086 ENSG00000188257 ENSG00000136997 ENSG00000095303 ENSG00000275565 ENSG00000269858 ENSG00000023445 ENSG00000087245 ENSG00000142192 ENSG00000100448 ENSG00000187840 ENSG00000108839 ENSG00000115884 ENSG00000145192 ENSG00000175899 ENSG00000026508 ENSG00000100234 ENSG00000153094 ENSG00000291971 ENSG00000198793 ENSG00000170558 ENSG00000148344 ENSG00000112715 ENSG00000124212 ENSG00000121879 ENSG00000164305 ENSG00000122194 ENSG00000163631 ENSG00000160049 ENSG00000129219 ENSG00000113520 ENSG00000120868 ENSG00000005339 ENSG00000157764 ENSG00000109320 ENSG00000173039 ENSG00000110324 ENSG00000073756 ENSG00000166135 ENSG00000100151 ENSG00000157766 ENSG00000177606 ENSG00000243646 ENSG00000100985 ENSG00000005381 ENSG00000171608 PMC9405677__F18 Arc Regulates Transcription of Genes for Plasticity, Excitability and Alzheimer’s Disease ENSG00000125740 ENSG00000164305 ENSG00000180210 ENSG00000106683 ENSG00000140937 ENSG00000102081 ENSG00000220205 ENSG00000157103 ENSG00000099365 ENSG00000132535 ENSG00000182580 ENSG00000064012 ENSG00000140443 ENSG00000095794 ENSG00000118058 ENSG00000142192 ENSG00000282830 ENSG00000125814 ENSG00000152495 ENSG00000164082 ENSG00000073756 ENSG00000139352 ENSG00000104327 ENSG00000117020 ENSG00000132872 ENSG00000125675 ENSG00000177606 ENSG00000198576 ENSG00000132164 ENSG00000101327 ENSG00000181195 ENSG00000168081 PMC6322225__F4 Treatment to health (HTD) network ENSG00000173599 ENSG00000175899 ENSG00000102977 PMC8301018__F5 3H-1,2-Dithiole-3-Thione Protects Lens Epithelial Cells against Fructose-Induced Epithelial-Mesenchymal Transition via Activation of AMPK to Eliminate AKR1B1-Induced Oxidative Stress in Diabetes Mellitus ENSG00000170558 ENSG00000085662 ENSG00000100985 PMC9307586__F12 MicroRNA expression profiling of endocrine sensitive and resistant breast cancer cell lines ENSG00000149201 ENSG00000110330 ENSG00000070831 ENSG00000150093 ENSG00000118971 ENSG00000112715 ENSG00000166147 ENSG00000080573 ENSG00000101558 ENSG00000204262 ENSG00000186340 ENSG00000168461 ENSG00000108375 ENSG00000168807 ENSG00000081052 ENSG00000134871 ENSG00000156011 ENSG00000148848 ENSG00000139219 ENSG00000117020 ENSG00000134013 ENSG00000134853 ENSG00000291748 ENSG00000107485 ENSG00000013297 PMC4918817__F2 Molecular circuitry of stem cell fate in skeletal muscle regeneration, ageing, and disease ENSG00000009709 ENSG00000111049 ENSG00000148400 PMC6925523__F3 Cellular signalling pathways in response to pathogenic viral infection or mtDNA release ENSG00000162711 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000276561 PMC8132124__F3 Surviving the odds: From perception to survival of fungal phytopathogens under host-generated oxidative burst ENSG00000149311 ENSG00000116649 PMC8596933__F6 CXCL14 facilitates the growth and metastasis of ovarian carcinoma cells via activation of the Wnt/Beta-catenin signaling pathway ENSG00000145824 ENSG00000168036 ENSG00000168646 PMC3140170__F10 Nicotine signal transduction pathways ENSG00000002330 PMC7685213__F1 Simple Rx for congenital erythropoietic porphyria ENSG00000066926 ENSG00000126088 ENSG00000158578 ENSG00000256269 ENSG00000188690 PMC5267352__F1 Reviving the promise of transcription factor Nrf2 based therapeutics for kidney diseases ENSG00000187097 ENSG00000181019 ENSG00000079999 PMC6193498__F1 Homology-directed repair (HDR) and other pathways for the repair of double-strand breaks (DSBs) ENSG00000012048 ENSG00000083093 ENSG00000051180 ENSG00000139618 PMC10813911__F3 Astroglial Cells: Emerging Therapeutic Targets in the Management of Traumatic Brain Injury ENSG00000131095 PMC1502564__F3 Model diagrams indicating regulation and function of E47 activity ENSG00000162676 ENSG00000165702 PMC3967838__F1 DNA2 Resolves Expanding Flap in Mitochondrial Base Excision Repair ENSG00000138346 PMC5450421__F4 Key enzymes in the glycolytic, pentose phosphate, pyruvate, and UDP-N-acetyl-galactosamine pathways are upregulated in the in vivo Giardia foci ENSG00000172005 PMC12222133__F3 Apoptosis in NPCs ENSG00000120868 ENSG00000168040 PMC12222133__F6 PANoptosis in NPCs ENSG00000278718 ENSG00000162711 ENSG00000124256 ENSG00000137275 ENSG00000138794 ENSG00000163568 ENSG00000142405 ENSG00000168040 ENSG00000168404 ENSG00000064012 ENSG00000164305 ENSG00000285379 PMC8274905__F6 Metformin Inhibits Lipoteichoic Acid–Induced Oxidative Stress and Inflammation Through AMPK/NRF2/NFKB Signaling Pathway in Bovine Mammary Epithelial Cells ENSG00000226275 ENSG00000125538 PMC6015873__F1 CAMKK2 as a molecular hub downstream in the bone–prostate cancer (PCa) microenvironment ENSG00000110931 ENSG00000168036 ENSG00000131196 ENSG00000213024 PMC5796897__F3 The fatty acid (FA) synthesis in different cell types ENSG00000131473 ENSG00000135218 ENSG00000042832 ENSG00000169710 PMC10778290__F7 Schematic diagram shows that tumor-derived ESM1 combines with the c-Met expressed by endothelial cells to promote GC peritoneal metastasis by inducing angiogenesis ENSG00000164283 ENSG00000100985 ENSG00000112715 PMC5064021__F9 Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals ENSG00000137265 ENSG00000149357 ENSG00000118520 PMC8535522__F1 Development of New Cancer Treatment by Identifying and Focusing the Genetic Mutations or Altered Expression in Gynecologic Cancers ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000198793 ENSG00000146648 ENSG00000139618 PMC8055404__F3 Long Noncoding RNA UCA1 in Gastrointestinal Cancers: Molecular Regulatory Roles and Patterns, Mechanisms, and Interactions ENSG00000162889 ENSG00000198793 ENSG00000168036 PMC3667790__F7 DSG3 Facilitates Cancer Cell Growth and Invasion through the DSG3-Plakoglobin-TCF/LEF-Myc/Cyclin D1/MMP Signaling Pathway ENSG00000137673 ENSG00000134757 PMC8602894__F7 Hsa_circRNA_103124 Upregulation in Crohn’s Disease Promotes Cell Proliferation and Inhibits Autophagy by Regulating the Hsa-miR-650/AKT2 Signaling Pathway ENSG00000123374 PMC5480600__F3 Tumor-Associated Macrophages as Treatment Targets in Oncology ENSG00000089012 ENSG00000166278 ENSG00000121807 PMC8148341__F2 Microglial Exosomes in Neurodegenerative Disease ENSG00000172680 ENSG00000111737 PMC8148341__F1 Microglial Exosomes in Neurodegenerative Disease ENSG00000100568 ENSG00000110651 ENSG00000010278 ENSG00000135404 ENSG00000151532 PMC8461092__F2 Interaction Between PEDV and Its Hosts: A Closer Look at the ORF3 Accessory Protein ENSG00000144895 ENSG00000136100 PMC5494974__F3 Haploinsufficient tumor suppressor genes ENSG00000149311 ENSG00000135446 ENSG00000177606 ENSG00000136997 ENSG00000123374 ENSG00000105810 PMC4545641__F1 The Expanding Role of Delta-like 4 Mediated Notch Signaling in Cardiovascular and Metabolic Diseases ENSG00000148400 ENSG00000074181 PMC5517784__F5 Figure illustrating cumulative flux index in glycolysis, TCA cycle and electron transport chain in glucose metabolic pathway ENSG00000105953 ENSG00000146701 ENSG00000062485 PMC8706317__F2 Improving the Health-Benefits of Kales (Brassica oleracea L. var. acephala DC) through the Application of Controlled Abiotic Stresses: A Review ENSG00000175793 ENSG00000079999 PMC5494974__F5 Haploinsufficient tumor suppressor genes ENSG00000157933 ENSG00000198742 PMC6042022__F7 Interactions between membrane–lipid metabolism, APP processing and Beta-secretase (BACE) activity, cholesterol uptake/efflux and cell cycle regulation ENSG00000123975 ENSG00000142192 ENSG00000130164 ENSG00000123374 ENSG00000160179 ENSG00000112378 ENSG00000166851 PMC8705541__F2 Thyroid Hormone Nuclear Receptor TRA1 and Canonical WNT Pathway Cross-Regulation in Normal Intestine and Cancer ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC11590683__F1 Catabolic pathways of glucose metabolism in KT2440 ENSG00000197713 ENSG00000153574 PMC6445864__F7 Schematic illustration showing anti-inflammatory responses in RAW 264.7 cells after treatment with AS-6 ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC4368090__F3 Interleukin-1B and its interacting proteins in Alzheimer’s disease ENSG00000002330 ENSG00000069482 ENSG00000213658 ENSG00000170458 ENSG00000186716 ENSG00000113520 ENSG00000166278 ENSG00000150455 ENSG00000146648 ENSG00000081189 ENSG00000062485 PMC6538222__F3 The Keap1-Nrf2-ARE pathway ENSG00000178573 ENSG00000100387 ENSG00000079999 PMC3154190__F5 Characterization of the MDSC Proteome Associated with Metastatic Murine Mammary Tumors Using Label-Free Mass Spectrometry and Shotgun Proteomics ENSG00000121552 ENSG00000148346 ENSG00000161905 ENSG00000110799 ENSG00000143878 ENSG00000163736 ENSG00000163737 ENSG00000137801 ENSG00000120899 ENSG00000198087 ENSG00000178732 ENSG00000220205 ENSG00000122705 ENSG00000118520 PMC9071071__F3 Early programming of reproductive health and fertility: novel neuroendocrine mechanisms and implications in reproductive medicine ENSG00000170498 ENSG00000074266 ENSG00000096717 PMC7306218__F4 Identification of hydatidosis-related modules and key regulatory genes ENSG00000156574 ENSG00000120885 ENSG00000184344 ENSG00000196620 PMC2929951__F8 Mapping Drug Physico-Chemical Features to Pathway Activity Reveals Molecular Networks Linked to Toxicity Outcome ENSG00000277586 ENSG00000110395 ENSG00000100285 ENSG00000100592 ENSG00000163235 ENSG00000291971 ENSG00000134982 ENSG00000177606 ENSG00000136997 ENSG00000168036 PMC4000238__F2 The canonical Wnt, Ihh, Bmp and PTH/PTHrP signaling pathways in regulating the differentiation of mesenchymal precursors ENSG00000139219 ENSG00000152266 ENSG00000125398 ENSG00000163501 PMC4000238__F1 Wnt pathway and its interactions with other pathways in bone ENSG00000152266 ENSG00000169071 ENSG00000134982 ENSG00000177606 ENSG00000185483 PMC9331941__F1 Immune Checkpoint Inhibitors in Cancer Therapy—How to Overcome Drug Resistance? ENSG00000089692 ENSG00000198053 ENSG00000181847 ENSG00000272398 ENSG00000168610 ENSG00000010671 PMC5912161__F1 Drug-Free Macromolecular Therapeutics Induce Apoptosis via Calcium Influx and Mitochondrial Signaling Pathway ENSG00000172005 ENSG00000188158 PMC3603002__F6 T cell signaling pathways and protein phosphorylation sites identified to be differential between NOD and B6g7 mice in stimulated cells ENSG00000213658 ENSG00000070831 ENSG00000110448 ENSG00000122224 ENSG00000163914 ENSG00000074966 ENSG00000076641 ENSG00000089159 ENSG00000160691 ENSG00000179295 PMC2661789__F1 In endothelial cells, after activation, VEGFR2 is able to stimulate the AKT/mTOR signalling pathway through PI3K ENSG00000163435 ENSG00000005882 ENSG00000112715 PMC3852343__F3 Oxygen-regulated COX subunit isoform switch in yeast and mammals ENSG00000179091 ENSG00000178741 PMC9658148__F3 Generation of Lens Progenitor Cells and Lentoid Bodies from Pluripotent Stem Cells: Novel Tools for Human Lens Development and Ocular Disease Etiology ENSG00000107859 ENSG00000186847 ENSG00000137203 ENSG00000156574 ENSG00000164690 ENSG00000126778 ENSG00000176165 PMC6325770__F7 Proposed CLIC4/Arf6 signaling pathway ENSG00000157985 ENSG00000135439 ENSG00000171759 ENSG00000165527 ENSG00000204217 ENSG00000111737 PMC9199004__F5 Major Downregulation of Circulating microRNAs in Zika Acutely Infected Patients: Potential Implications in Innate and Adaptive Immune Response Signaling Pathways ENSG00000171855 ENSG00000147649 ENSG00000099985 ENSG00000153094 ENSG00000108551 ENSG00000120889 ENSG00000169032 ENSG00000119383 ENSG00000168610 ENSG00000160691 ENSG00000239732 ENSG00000133048 ENSG00000145623 ENSG00000105397 ENSG00000115415 ENSG00000149968 ENSG00000177606 ENSG00000136869 ENSG00000175104 ENSG00000067955 ENSG00000184216 PMC9199004__F4 Major Downregulation of Circulating microRNAs in Zika Acutely Infected Patients: Potential Implications in Innate and Adaptive Immune Response Signaling Pathways ENSG00000107798 ENSG00000173327 ENSG00000164933 ENSG00000164305 ENSG00000008083 ENSG00000177426 ENSG00000112242 ENSG00000073060 ENSG00000102081 ENSG00000153879 ENSG00000137265 ENSG00000139726 ENSG00000104432 ENSG00000162896 ENSG00000115008 ENSG00000100697 ENSG00000143933 ENSG00000125347 ENSG00000169245 ENSG00000111537 ENSG00000142089 ENSG00000172936 ENSG00000166224 ENSG00000067955 ENSG00000159399 PMC6385418__F1 Homologous recombination (HR) repair deficiency represents an opportunity for a synthetic lethality approach through the use of PARP inhibitors (PARPi) ENSG00000143799 ENSG00000138385 PMC9199004__F7 Major Downregulation of Circulating microRNAs in Zika Acutely Infected Patients: Potential Implications in Innate and Adaptive Immune Response Signaling Pathways ENSG00000070831 ENSG00000291971 PMC3978568__F1 Schematic representation and overview of PTEN/PI3K/AKT signaling and a model of the mechanism of peroxisome proliferator-activated receptor (PPAR) action ENSG00000198793 ENSG00000168036 PMC11123998__F5 Supplementation influences the metabolic reprogramming of cumulus cells in aging ovarian patients ENSG00000074800 ENSG00000073578 ENSG00000100412 ENSG00000117118 ENSG00000159399 ENSG00000062485 PMC6243101__F1 Autophagy as an anti-inflammatory process ENSG00000150782 ENSG00000125538 ENSG00000198793 PMC8339131__F8 TRAIP as a key prognostic DEG between CTCs and metastatic lesions in osteosarcoma ENSG00000183763 ENSG00000107104 PMC8444451__F4 Identification of microRNAs and gene regulatory networks in cleft lip common in humans and mice ENSG00000004975 ENSG00000154342 ENSG00000187140 ENSG00000120868 ENSG00000164690 ENSG00000168646 ENSG00000176165 ENSG00000178919 PMC4376601__F1 Sphingosine-1-phosphate receptor 2: a novel bile acid receptor and regulator of hepatic lipid metabolism? ENSG00000160867 ENSG00000138823 ENSG00000167910 ENSG00000169047 ENSG00000100979 ENSG00000267534 PMC3096022__F1 Biochemical pathways leading to the synthesis of TAG and cholesterol ENSG00000113161 ENSG00000169710 ENSG00000099194 PMC4737457__F4 Crosstalk between Wnt, Notch, and JAK-STAT signaling pathways ENSG00000168214 ENSG00000168610 PMC11039990__F7 Genomic overview of INA-induced NPR1 targeting and transcriptional cascades in Arabidopsis ENSG00000148798 PMC8306599__F2 Advanced Glycation End Products: New Clinical and Molecular Perspectives ENSG00000115415 ENSG00000162692 PMC4621888__F1 Mastocytosis: a mutated KIT receptor induced myeloproliferative disorder ENSG00000157404 ENSG00000033327 ENSG00000171456 ENSG00000115415 ENSG00000149269 ENSG00000067900 ENSG00000168610 PMC11147929__F6 LSS affects endothelial cell pyroptosis through IKKE/STAT1/NLRP3 signaling pathway ENSG00000278718 ENSG00000162711 ENSG00000150782 ENSG00000115415 PMC3192838__F7 Hepatitis C Virus Reveals a Novel Early Control in Acute Immune Response ENSG00000088888 ENSG00000187608 ENSG00000144895 ENSG00000131323 ENSG00000121060 PMC11858545__F8 Danggui Beimu Kushen Pill Alleviates Colitis-Induced Inflammation in Mice by Regulating the IL-6/IL-6R and IL-17A/IL-17RA Signaling Pathways ENSG00000175104 ENSG00000168610 PMC4600500__F4 Interactomic analysis by ingenuity pathway analysis (IPA) of significant molecules ENSG00000108691 ENSG00000111537 ENSG00000173039 ENSG00000169429 ENSG00000162924 PMC4772101__F2 Mechanical signaling and tissue growth ENSG00000168036 PMC8825714__F5 UHPLC‐QTOF/MS‐based comparative metabolomics in pectoralis major of fast‐ and slow‐growing chickens at market ages ENSG00000125772 ENSG00000087085 ENSG00000173868 ENSG00000006007 PMC8024479__F3 Intrinsic apoptotic pathway ENSG00000063176 ENSG00000128272 ENSG00000144895 ENSG00000127191 ENSG00000115317 PMC5037772__F5 Pin1 regulates multiple signal transductions in metabolic organs ENSG00000127445 ENSG00000164935 ENSG00000169047 ENSG00000168036 ENSG00000168610 ENSG00000081189 ENSG00000160741 PMC8458575__F2 Metabolic Reprogramming of Immune Cells at the Maternal-Fetal Interface and the Development of Techniques for Immunometabolism ENSG00000065911 ENSG00000128272 ENSG00000084774 PMC5037772__F4 Pin1 has biphasic effects on insulin signaling ENSG00000124102 ENSG00000127445 ENSG00000169047 PMC6089072__F3 Methods for observation and quantification of apoptosis ENSG00000254550 ENSG00000026103 PMC7276052__F7 Main components of RAAS pathway active in small bowel (SB) Crohn’s disease (left) compared to non-IBD (right) ENSG00000174358 ENSG00000130234 PMC7826706__F1 Hedgehog (Hh) signaling pathway contributes to hepatic carcinogenesis ENSG00000103222 ENSG00000026508 ENSG00000128602 PMC6403405__F8 Functional mechanisms of COL2A1 on the BMP-SMAD1 pathway ENSG00000170365 ENSG00000140678 ENSG00000150093 ENSG00000204217 PMC8389254__F3 Hypoxia Signaling in Parkinson’s Disease: There Is Use in Asking “What HIF?” ENSG00000177169 ENSG00000198793 ENSG00000005893 PMC6942938__F1 Proteome alterations in aqueous humour of primary open angle glaucoma patients ENSG00000156076 ENSG00000050165 ENSG00000115266 ENSG00000168036 ENSG00000125084 PMC11360076__F4 Protein–protein interaction map of the upstream regulators that significantly altered after the exposure to V ENSG00000155506 ENSG00000128641 ENSG00000059804 ENSG00000119969 ENSG00000178980 ENSG00000146457 ENSG00000139625 ENSG00000137845 ENSG00000137764 ENSG00000183018 ENSG00000163694 ENSG00000009950 ENSG00000011422 ENSG00000292234 ENSG00000072210 ENSG00000102081 ENSG00000170043 ENSG00000188404 ENSG00000197386 ENSG00000125850 ENSG00000051180 ENSG00000100219 ENSG00000125656 ENSG00000142552 ENSG00000077279 ENSG00000116741 ENSG00000109654 ENSG00000160679 ENSG00000134900 ENSG00000111012 ENSG00000138378 ENSG00000158290 ENSG00000128272 ENSG00000164136 ENSG00000069248 ENSG00000183495 ENSG00000163082 PMC2730725__F1 Nm23-H1suppression of tumor metastasis may depend on at least three pathways ENSG00000023734 ENSG00000198910 PMC3248218__F3 NUAK2: an emerging acral melanoma oncogene ENSG00000198793 PMC6628314__F1 Preclinical Characteristics of the Irreversible Pan-HER Kinase Inhibitor Neratinib Compared with Lapatinib: Implications for the Treatment of HER2-Positive and HER2-Mutated Breast Cancer ENSG00000291971 ENSG00000158458 ENSG00000146648 ENSG00000169752 PMC4544004__F8 The Architecture of the TIR Domain Signalosome in the Toll-like Receptor-4 Signaling Pathway ENSG00000172005 ENSG00000136869 ENSG00000131323 ENSG00000168040 ENSG00000175104 PMC9116428__F1 Strategies for Biomaterial-Based Spinal Cord Injury Repair via the TLR4-NFKB Signaling Pathway ENSG00000108691 ENSG00000102871 ENSG00000198793 ENSG00000169429 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000130159 ENSG00000168040 ENSG00000175104 ENSG00000127191 PMC4544004__F1 Architecture of the TIR Domain Signalosome in the Toll-like Receptor-4 Signaling Pathway ENSG00000174125 ENSG00000239732 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000168040 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC8175077__F2 Intracellular Free Neu5Ac Metabolism and Associated Genetic Disorders ENSG00000159921 ENSG00000135838 ENSG00000164414 ENSG00000119899 PMC10993482__F5 Gal-1 pathways promoting EMT in cancer ENSG00000198793 ENSG00000168036 ENSG00000136869 ENSG00000170989 PMC10993482__F4 Gal-1- and Gal-3 pathways promoting EMT in fibrosis ENSG00000168036 PMC5731874__F6 Osteopontin production by TM4SF4 signaling drives a positive feedback autocrine loop with the STAT3 pathway to maintain cancer stem cell-like properties in lung cancer cells ENSG00000169903 ENSG00000291971 ENSG00000026508 ENSG00000168036 ENSG00000168610 PMC4032097__F9 CNTF-induced gliosis in the retina after ONC and Pen1-C6DN + siCASP2 treatment ENSG00000242689 ENSG00000122756 ENSG00000138794 PMC7829348__F2 Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions ENSG00000183735 ENSG00000170458 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC11566834__F8 Optogenetic stimulation of the “Zusanli” acupoint alleviates inflammatory pain through active Wnt/Beta-Catenin and MAPK signaling pathway in rats ENSG00000134982 ENSG00000168036 PMC10993482__F6 Gal-3, Gal-4 and Gal-8 pathways to EMT in cancer ENSG00000168036 ENSG00000146648 ENSG00000140443 PMC9496846__F4A Systematic Analysis of Genetic and Pathway Determinants of Eribulin Sensitivity across 100 Human Cancer Cell Lines from the Cancer Cell Line Encyclopedia (CCLE) ENSG00000142192 ENSG00000186395 ENSG00000140262 ENSG00000108055 ENSG00000138798 ENSG00000101558 ENSG00000110395 ENSG00000132646 ENSG00000136997 ENSG00000001626 ENSG00000146648 ENSG00000184575 ENSG00000102974 PMC2901811__F4 II S and TOR-signaling pathway in Drosophila PMC11011897__F3 Proteomic Analysis of Salivary Extracellular Vesicles from COVID-19 Patients Reveals a Specific Anti-COVID-19 Response Protein Signature ENSG00000142798 ENSG00000130702 ENSG00000120885 ENSG00000134871 ENSG00000108821 ENSG00000166147 ENSG00000171560 ENSG00000163631 PMC10458543__F5 Protein interaction network created using STRING database based on Bos taurus genome ENSG00000110944 ENSG00000243414 ENSG00000171855 ENSG00000162711 ENSG00000109320 ENSG00000276561 ENSG00000142166 ENSG00000169245 ENSG00000239732 ENSG00000105397 ENSG00000172936 ENSG00000175104 ENSG00000164342 PMC7491318__F11 Protein interaction network for 105 DAPs listed in ENSG00000167601 ENSG00000104812 ENSG00000122694 ENSG00000104324 ENSG00000080608 ENSG00000181061 ENSG00000168894 ENSG00000100227 ENSG00000105258 ENSG00000113621 ENSG00000168002 ENSG00000164934 ENSG00000236625 ENSG00000138778 ENSG00000157227 ENSG00000083444 ENSG00000106070 ENSG00000183624 ENSG00000108821 ENSG00000143179 ENSG00000078808 ENSG00000142552 ENSG00000123975 ENSG00000284832 ENSG00000106333 ENSG00000198860 ENSG00000140264 ENSG00000161888 ENSG00000221968 ENSG00000117399 ENSG00000107223 ENSG00000127586 ENSG00000068028 ENSG00000180447 ENSG00000122952 ENSG00000151366 ENSG00000189043 ENSG00000142546 ENSG00000152952 ENSG00000137804 ENSG00000163064 ENSG00000242616 ENSG00000284868 ENSG00000160584 ENSG00000139209 ENSG00000276463 ENSG00000113140 ENSG00000066135 ENSG00000073756 ENSG00000174307 ENSG00000115946 ENSG00000162733 ENSG00000034510 ENSG00000137575 ENSG00000156535 ENSG00000047315 PMC7583982__F2 Functions of miRNAs in EOC metastasis ENSG00000170558 ENSG00000198793 PMC3075242__F6 Differential Expression of MicroRNAs in Tumors from Chronically Inflamed or Genetic (APCMin/+) Models of Colon Cancer ENSG00000149311 ENSG00000099330 ENSG00000138795 ENSG00000002330 ENSG00000134982 ENSG00000177606 ENSG00000136997 ENSG00000168040 ENSG00000119912 ENSG00000132693 ENSG00000080839 ENSG00000196712 PMC5882792__F1 Mitochondrial UPRmt and UPRam stress response pathways ENSG00000088888 ENSG00000128272 ENSG00000169136 ENSG00000125656 PMC8553480__F3 MicroRNAs as Biomarkers for Early Diagnosis, Prognosis, and Therapeutic Targeting of Ovarian Cancer ENSG00000087245 ENSG00000169554 ENSG00000118526 ENSG00000150672 ENSG00000020633 ENSG00000168036 ENSG00000166670 ENSG00000112715 PMC9555037__F7 Ruscogenin Protects Against Deoxynivalenol-Induced Hepatic Injury by Inhibiting Oxidative Stress, Inflammation, and Apoptosis Through the Nrf2 Signaling Pathway: An In vitro Study ENSG00000181019 ENSG00000079999 PMC8553480__F2 MicroRNAs as Biomarkers for Early Diagnosis, Prognosis, and Therapeutic Targeting of Ovarian Cancer ENSG00000124571 ENSG00000128191 ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC2776915__F1 A genetic model for sex determination, controlled by a balance of antagonistic pathways ENSG00000162552 ENSG00000169218 ENSG00000186766 ENSG00000125398 ENSG00000168036 ENSG00000102678 PMC7325493__F1 Complex Signaling Network Driving Macropinocytosis in Cancer ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000146648 PMC3249400__F1 AMP-activated protein kinase (AMPK) signaling pathway coordinates cell growth, autophagy, & metabolism ENSG00000104812 ENSG00000177169 ENSG00000174996 ENSG00000107862 ENSG00000169047 ENSG00000061273 ENSG00000110931 ENSG00000160741 ENSG00000108840 PMC7291262__F2 MiRNAs/CD133 axis in glioblastoma signaling pathways ENSG00000129219 ENSG00000164690 PMC3249400__F2 AMP-activated protein kinase (AMPK) signaling pathway coordinates cell growth, autophagy, & metabolism ENSG00000149311 ENSG00000177169 ENSG00000010810 ENSG00000198793 ENSG00000217128 ENSG00000196712 PMC6332464__F2 Schematic representation of glycolysis, the pentose phosphate pathway (PPP), glutaminolysis and lipid synthesis and their inhibition by polyphenols in breast cancer cells ENSG00000180210 ENSG00000092621 PMC8421037__F2 YAP/TAZ activity is central to coordinating cell migration ENSG00000110237 ENSG00000146376 ENSG00000197905 ENSG00000007866 ENSG00000074219 ENSG00000137801 PMC8421037__F1 Mitosis by the Hippo pathway and YAP/TAZ ENSG00000134982 ENSG00000197905 ENSG00000176386 ENSG00000007866 ENSG00000150457 ENSG00000132964 ENSG00000131023 ENSG00000102974 ENSG00000074219 PMC3249400__F4 AMP-activated protein kinase (AMPK) signaling pathway coordinates cell growth, autophagy, & metabolism ENSG00000169710 ENSG00000096717 ENSG00000108840 PMC8136213__F7 Symbiotic relationship between Caenorhabditis elegans and members of its microbiome contributes to worm fitness and lifespan extension ENSG00000205795 ENSG00000291814 ENSG00000118515 PMC11936079__F3 Involvement of EMR2 in Wnt/Beta-catenin signaling pathway ENSG00000162493 ENSG00000108654 ENSG00000173467 ENSG00000196712 PMC8760362__F2 Zika virus infection of the placenta alters extracellular matrix proteome ENSG00000157404 ENSG00000145192 ENSG00000111837 ENSG00000115271 ENSG00000204520 PMC3145765__F9 Cardiomyocyte Specific Ablation of p53 Is Not Sufficient to Block Doxorubicin Induced Cardiac Fibrosis and Associated Cytoskeletal Changes ENSG00000047849 ENSG00000164305 PMC8772744__F5 Molecular Mechanistic Pathways Targeted by Natural Antioxidants in the Prevention and Treatment of Chronic Kidney Disease PMC8772744__F4 Molecular Mechanistic Pathways Targeted by Natural Antioxidants in the Prevention and Treatment of Chronic Kidney Disease ENSG00000079999 PMC3070572__F4 Schematic analysis of the regulatory pathways in BOO in AROM+/6J male mice ENSG00000132646 ENSG00000291748 PMC4648799__F2 P2Y receptor (P2YR) signaling in neurons counteracts oxidative stress and Alzheimer’s pathology ENSG00000142192 ENSG00000137845 PMC8772744__F2 Molecular Mechanistic Pathways Targeted by Natural Antioxidants in the Prevention and Treatment of Chronic Kidney Disease ENSG00000177169 ENSG00000198793 PMC8772744__F1 Molecular Mechanistic Pathways Targeted by Natural Antioxidants in the Prevention and Treatment of Chronic Kidney Disease ENSG00000137275 ENSG00000102871 ENSG00000172936 ENSG00000166278 ENSG00000168040 ENSG00000127191 ENSG00000184216 PMC2828280__F2 Canonical Wnt pathway ENSG00000281324 ENSG00000137673 ENSG00000162337 ENSG00000149968 ENSG00000156299 ENSG00000134982 ENSG00000168036 ENSG00000137845 PMC4061726__F1 Targeting Wnt signaling at the neuroimmune interface for dopaminergic neuroprotection/repair in Parkinson’s disease ENSG00000138795 ENSG00000169071 ENSG00000162337 ENSG00000070831 ENSG00000134982 ENSG00000133067 PMC3701522__F1 Wnt signalling pathways implicated in diabetic nephropathy ENSG00000070831 ENSG00000100592 ENSG00000134982 ENSG00000168036 ENSG00000132478 PMC6385756__F7 Diagram depicting the prostanoid synthesis pathway and the effects of PGE2 on its receptor subtypes ENSG00000183134 ENSG00000122420 ENSG00000050628 ENSG00000160013 ENSG00000125384 ENSG00000095303 ENSG00000148344 ENSG00000106853 ENSG00000164120 ENSG00000073756 ENSG00000160951 PMC8123861__F1 PGC-1A in the Mitochondrial NAD+ Pool in Metabolic Diseases ENSG00000105835 ENSG00000157064 ENSG00000173614 PMC5588108__F3 The Hedgehog signaling pathway ENSG00000168283 ENSG00000164690 ENSG00000128602 PMC3705708__F1 Hedgehog Signal Transduction Network ENSG00000144857 ENSG00000166813 ENSG00000128602 PMC9024590__F3 Boolean Model of the Proliferative Role of the lncRNA XIST in Non-Small Cell Lung Cancer Cells ENSG00000149311 PMC7583982__F1 Biogenesis and functions of miRNA ENSG00000135473 ENSG00000152520 ENSG00000128191 ENSG00000113360 PMC2648546__F8 A new feedback loop for p53 pathway ENSG00000123374 PMC9271889__F5 Autophagy in health and disease: From molecular mechanisms to therapeutic target ENSG00000177169 ENSG00000130234 ENSG00000099940 ENSG00000145782 ENSG00000166471 ENSG00000136874 PMC3936891__F1 Overview of the folate-methionine metabolic pathway investigated in this study ENSG00000124275 PMC9218499__F1 Taste Receptors in Innate Immunity and Oral Health ENSG00000185933 ENSG00000070985 ENSG00000166090 ENSG00000137841 PMC6789489__F1 Action of methylxanthine (MTXs) in glioblastoma (GBM) ENSG00000198793 ENSG00000196591 ENSG00000131095 PMC10034056__F2 Effect of Bifidobacterium on osteoclasts: TNFA/NFKB inflammatory signal pathway-mediated mechanism ENSG00000175104 ENSG00000131196 PMC10034056__F1 Effect of Bifidobacterium on osteoclasts: TNFA/NFKB inflammatory signal pathway-mediated mechanism ENSG00000102871 ENSG00000127191 ENSG00000131196 PMC2676446__F1 Regulation of p53 and MDM2 and the outcomes of p53 activation ENSG00000149311 ENSG00000175054 ENSG00000026103 PMC8834112__F4 Drosophila melanogaster: A Model System to Study Distinct Genetic Programs in Myoblast Fusion ENSG00000124102 ENSG00000143761 ENSG00000149269 PMC6441234__F1 Illustrative diagram for exosome-mediated transfer of therapeutic resistance in the tumor microenvironment (TME) ENSG00000074319 ENSG00000010278 ENSG00000135404 ENSG00000185272 ENSG00000146648 PMC9035423__F4 Lactate-induced effects on bovine granulosa cells are mediated via PKA signaling ENSG00000112303 ENSG00000138039 ENSG00000116741 PMC6637313__F1 Cellular and molecular responses to extracellular and intracellular DNA ENSG00000213918 ENSG00000164430 ENSG00000105612 ENSG00000111537 ENSG00000186716 ENSG00000189403 ENSG00000172936 ENSG00000163687 PMC5087334__F6 MALT1 protease activation triggers acute disruption of endothelial barrier integrity via CYLD cleavage ENSG00000038382 ENSG00000163914 ENSG00000083799 PMC10531837__F2 Exploring the Complex and Multifaceted Interplay between Melanoma Cells and the Tumor Microenvironment ENSG00000157764 ENSG00000134982 ENSG00000196712 PMC10531837__F1 Melanin production ENSG00000185664 ENSG00000080166 ENSG00000107165 PMC10531837__F4 Phenotype switching in melanoma ENSG00000167601 ENSG00000169554 ENSG00000135903 ENSG00000187140 ENSG00000076706 ENSG00000100146 ENSG00000064300 ENSG00000196628 ENSG00000110693 ENSG00000124216 ENSG00000125398 ENSG00000122691 ENSG00000008196 ENSG00000177606 ENSG00000019549 ENSG00000137265 ENSG00000080166 ENSG00000078098 ENSG00000146648 PMC10886467__F2 An illustrative representation and overview of PINK1, Parkin, and related molecules in the regulatory pathway for mitophagy ENSG00000183735 ENSG00000123240 ENSG00000175193 ENSG00000116688 ENSG00000158828 ENSG00000171109 PMC7790891__F2 Regulatory network of ginsenosides in macrophage ENSG00000198793 ENSG00000132693 ENSG00000139687 PMC9214054__F8 Gentiopicroside targets PAQR3 to activate the PI3K/AKT signaling pathway and ameliorate disordered glucose and lipid metabolism ENSG00000134574 ENSG00000163291 PMC7790891__F1 Regulatory mechanisms of ginsenosides in HUVEC ENSG00000162692 ENSG00000139687 ENSG00000079999 PMC6643028__F1 GPCR signaling ENSG00000070831 ENSG00000198793 ENSG00000163914 ENSG00000168036 ENSG00000164690 PMC6313651__F1 Gut Microbiota, Fusobacteria, and Colorectal Cancer ENSG00000181847 ENSG00000168036 ENSG00000106546 PMC5237710__F2 PI3K/Akt/mTOR pathway involved in tumorigenesis and metastasis ENSG00000002330 PMC3368076__F6 Proposed mechanisms of leptin and glucocorticoid stress hormones in the GSK3B/Beta-catenin signaling pathway ENSG00000168036 ENSG00000168610 PMC10886467__F1 Relevant signaling pathway potentially being involved in the pathogenesis of polycystic kidney disease (PKD) and/or chronic kidney disease (CKD) ENSG00000198793 ENSG00000164327 PMC3832598__F7 CD43 Promotes Cells Transformation by Preventing Merlin-Mediated Contact Inhibition of Growth ENSG00000026103 PMC3399969__F5 State-of-the-science: An update on renal cell carcinoma PMC7147542__F2 Sonic hedgehog (SHH) pathway ENSG00000164690 ENSG00000128602 PMC9532747__F1 MicroRNAs: Potential mediators between particulate matter 2.5 and Th17/Treg immune disorder in primary membranous nephropathy ENSG00000171759 ENSG00000106546 PMC12133616__F5 Stepwise presentation of the NF-kB signaling pathway ENSG00000149273 PMC6713153__F2 Signalling pathway induced by ManLAM ENSG00000174125 ENSG00000172936 PMC7136098__F2 Signaling options initiated via wnt5a and the concluded outcome ENSG00000178860 ENSG00000169071 ENSG00000100592 ENSG00000163914 ENSG00000131196 PMC8522911__F1 Toll-Like Receptors as a Therapeutic Target in the Era of Immunotherapies ENSG00000174125 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC10571545__F5 TF–FVIIa–driven PAR2 activation triggers EV generation from human TNBC cells, which promotes EMT in non–metastatic breast cancer cells, leading to the induction of proliferation, migration, invasion, and anti–apoptosis ENSG00000170558 PMC8367394__F12 PPAR signaling pathway regulated by high the concentration of ciglitazone ENSG00000150991 ENSG00000100979 ENSG00000165269 PMC7136098__F1 Canonical and noncanonical signaling options initiated via wnt3a and the concluded outcome ENSG00000178860 ENSG00000154342 ENSG00000281324 ENSG00000162337 ENSG00000100592 ENSG00000134982 ENSG00000163914 ENSG00000168036 ENSG00000131196 PMC3381650__F3 Signaling Networks of the Herpesvirus Entry Mediator (TNFRSF14) in Immune Regulation ENSG00000134982 PMC6317263__F2 Milk exosomes and allergy prevention ENSG00000113263 ENSG00000049768 PMC3109223__F1 MTOR signaling pathway ENSG00000168036 PMC5612430__F1 Choline and methyl group metabolism and its relation to DNA methylation and influence on regulation of gene expression: a simplified diagram ENSG00000151224 ENSG00000016391 ENSG00000116984 PMC4174543__F3 Activated STING in a Vascular and Pulmonary Syndrome ENSG00000183735 ENSG00000164430 ENSG00000105397 PMC10570830__F2 PIFs are the key regulators of skotomorphogenesis ENSG00000110934 ENSG00000167986 ENSG00000140543 PMC4958499__F1 Looking beyond structure: membrane phospholipids of skeletal muscle mitochondria ENSG00000173599 ENSG00000102125 ENSG00000133027 PMC6953096__F4 Representation of DEGs in major signal transduction pathways, in 5a treated cells ENSG00000198793 ENSG00000163914 ENSG00000127948 PMC3866156__F1 Proposed mechanisms of aspirin, the single nucleotide polymorphism rs6983267, and their interaction on the WNT/CTNNB1 pathway ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC9028943__F2 Fate of Leydig Cells in Men with Spermatogenic Failure PMC4582105__F3 Defects in ribosomal biogenesis activate p53 and other stress-response mechanisms ENSG00000101751 ENSG00000136997 ENSG00000166169 PMC8301837__F3 Wrestling and Wrapping: A Perspective on SUMO Proteins in Schwann Cells ENSG00000161956 ENSG00000149269 ENSG00000112561 PMC8301837__F2 Wrestling and Wrapping: A Perspective on SUMO Proteins in Schwann Cells ENSG00000148400 ENSG00000149269 ENSG00000100146 PMC6707613__F9 Synergistic effect of nano-selenium and metformin on type 2 diabetic rat model: Diabetic complications alleviation through insulin sensitivity, oxidative mediators and inflammatory markers ENSG00000169047 PMC3482395__F2 Canonical biogenesis pathway and mechanisms of miRNA deregulation ENSG00000136997 ENSG00000128191 ENSG00000113360 PMC9164068__F6 Luteolin on Human Breast Cancer Using Gene Expression Array: Inferring Novel Genes ENSG00000112367 ENSG00000160194 ENSG00000231021 ENSG00000142192 ENSG00000000971 ENSG00000235194 ENSG00000103888 ENSG00000112715 ENSG00000169760 ENSG00000073464 ENSG00000213625 ENSG00000137801 ENSG00000010244 ENSG00000091986 ENSG00000221823 ENSG00000104140 ENSG00000134057 ENSG00000113296 ENSG00000167941 ENSG00000277263 ENSG00000198670 ENSG00000136235 ENSG00000184985 ENSG00000169174 PMC7376433__F1 Molecular pathways involved in hereditary cancer risk ENSG00000149311 ENSG00000083093 ENSG00000198793 ENSG00000095002 ENSG00000196712 ENSG00000122512 ENSG00000183765 PMC6406288__F3 Consequences of indoleamine 2,3 dioxygenase (IDO) overexpression on the antitumoral immune response ENSG00000157404 ENSG00000111537 ENSG00000175832 ENSG00000106546 PMC7343507__F7 The regulatory role of miR-9 and miR-29a in DPN ENSG00000164690 ENSG00000016082 PMC3074148__F5 Schematic representation of the two degradation pathways followed by MicA ENSG00000169397 ENSG00000204520 PMC9269291__F5 Potentilla paradoxa Nutt. Ethanol Extract Exhibits Anti-Inflammatory Effects by Suppression of the Src/NFKB Signaling Pathway ENSG00000291971 ENSG00000172936 ENSG00000136869 PMC8773732__F1 Macrophage Involvement in Medication-Related Osteonecrosis of the Jaw (MRONJ): A Comprehensive, Short Review ENSG00000162711 ENSG00000111537 ENSG00000115415 ENSG00000125538 ENSG00000163914 ENSG00000136869 ENSG00000175104 PMC8657824__F1 The Membrane Trafficking of the Mechanosensitive Ion Channels TRPV1 and TRPV4 by Zonular Tension, Osmotic Stress and Activators in the Mouse Lens ENSG00000143867 ENSG00000196689 PMC4822134__F2 Ubiquitin regulation of TLR signaling ENSG00000174125 ENSG00000183735 ENSG00000173039 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000184216 ENSG00000164342 PMC151358__F5 JNK-dependent apoptosis signaling pathway ENSG00000104081 ENSG00000115317 PMC7007115__F2 Dietary Restriction PMC4822134__F1 Main signaling pathways of PRRs ENSG00000174125 ENSG00000167207 ENSG00000150455 ENSG00000127191 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000187554 ENSG00000082512 ENSG00000134070 ENSG00000136869 ENSG00000157625 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC7175140__F6 TGFB non-SMAD signaling pathways ENSG00000137834 ENSG00000070831 ENSG00000198742 ENSG00000175104 ENSG00000168610 ENSG00000076604 PMC7175140__F3 TGFB/SMAD signaling pathway PMC8695973__F2 Multiple Functions of the Dmrt Genes in the Development of the Central Nervous System ENSG00000142700 ENSG00000176399 ENSG00000170370 ENSG00000064218 ENSG00000176165 ENSG00000139352 PMC7398577__F3 Viral miR-mediated evasion of adaptive immune responses ENSG00000169248 ENSG00000216490 ENSG00000231179 ENSG00000204520 PMC7398577__F2 Viral miR-mediated suppression of host innate immune pathways ENSG00000174125 ENSG00000150455 ENSG00000168610 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000088888 ENSG00000170458 ENSG00000134070 ENSG00000136869 ENSG00000157625 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC8935981__F8 Comprehensive Analysis of Prognostic and Genetic Signatures for General Transcription Factor III (GTF3) in Clinical Colorectal Cancer Patients Using Bioinformatics Approaches ENSG00000168036 PMC3527608__F6 Green Tea Polyphenols Induce p53-Dependent and p53-Independent Apoptosis in Prostate Cancer Cells through Two Distinct Mechanisms ENSG00000159224 ENSG00000002330 ENSG00000171791 ENSG00000168040 ENSG00000026103 PMC8935981__F7 Comprehensive Analysis of Prognostic and Genetic Signatures for General Transcription Factor III (GTF3) in Clinical Colorectal Cancer Patients Using Bioinformatics Approaches ENSG00000149311 ENSG00000175054 ENSG00000143379 ENSG00000111837 ENSG00000095015 ENSG00000188130 ENSG00000116030 ENSG00000132341 PMC8935981__F9 Comprehensive Analysis of Prognostic and Genetic Signatures for General Transcription Factor III (GTF3) in Clinical Colorectal Cancer Patients Using Bioinformatics Approaches ENSG00000169710 ENSG00000099194 ENSG00000095794 PMC2833108__F7 TNFSFR and NFKB signaling activation during macrophage activation: CpG late responses ENSG00000132906 ENSG00000102871 ENSG00000138794 ENSG00000177606 ENSG00000056558 ENSG00000172936 ENSG00000131323 ENSG00000168040 ENSG00000175104 ENSG00000064012 ENSG00000164305 ENSG00000084774 PMC8268514__F1 Review of mechanisms of disease across PIK3CA-related disorders with vascular manifestations ENSG00000002330 ENSG00000070831 ENSG00000291971 ENSG00000198793 PMC2833108__F6 Sonic Hedgehog, Wnt and TGFB signaling pathway gene expression in CpG late treated macrophages [; ; ; ], see discussion ENSG00000134982 ENSG00000168036 ENSG00000164690 ENSG00000154654 ENSG00000128602 PMC7052372__F2 Innate immune receptors present in cholangiocytes ENSG00000162711 ENSG00000088888 ENSG00000172936 ENSG00000136869 ENSG00000184216 ENSG00000164342 PMC3241960__F5 Sarcolemmal actin assembly and nuclear signaling ENSG00000163914 ENSG00000172005 PMC9694420__F1 PIK3CAMutations in Breast Cancer Subtypes Other Than HR-Positive/HER2-Negative ENSG00000124102 ENSG00000166278 ENSG00000010671 PMC8348432__F8 Trans-(−)-Kusunokinin: A Potential Anticancer Lignan Compound against HER2 in Breast Cancer Cell Lines? ENSG00000134057 ENSG00000135446 ENSG00000006451 ENSG00000105810 PMC9446754__F5 CD47 as a promising therapeutic target in oncology ENSG00000164654 PMC3624606__F1 Oncogenes and tumor suppressor modulate metabolic reprograming in cancer cells ENSG00000136997 ENSG00000078237 ENSG00000115419 PMC6754502__F5 Broiler thymus predicted to have less cell migration in response to the Thermoneutral + LPS treatment compared to Fayoumi ENSG00000143878 ENSG00000184371 ENSG00000187908 ENSG00000213694 PMC4405775__F1 Dependence on signaling pathways based upon tumor suppressor status ENSG00000124102 ENSG00000291971 ENSG00000168610 PMC5118777__F3 Schematic indicating the role of cellular and EBV miRNAs in EBV latency and reactivation ENSG00000169554 ENSG00000172216 ENSG00000010818 PMC3520003__F1 Simplified summary of the role of ATGL in macrophages.FFAs which are taken up by macrophages are incorporated into TGs (and cholesteryl esters) ENSG00000042832 ENSG00000070831 PMC10905161__F2 Nrf2/Keap1 signaling pathway ENSG00000177169 ENSG00000065911 ENSG00000136436 ENSG00000135218 ENSG00000181019 ENSG00000100387 ENSG00000023909 ENSG00000156273 ENSG00000079999 ENSG00000026103 PMC3779571__F1 Chondrocyte gene network of CSGalNAcT-1 was classified as glycan biosynthesis and metabolism and functional pathway ENSG00000123989 ENSG00000168282 ENSG00000173039 ENSG00000213625 ENSG00000111962 PMC6027307__F1 Noncanonical NFKB signaling pathway ENSG00000104856 ENSG00000131323 ENSG00000127191 PMC7304783__F6 Possible mechanism associated with the tumor-suppressing effect of Romidepsin in DEN-induced HCC mouse model ENSG00000281324 ENSG00000002330 ENSG00000168036 ENSG00000083799 PMC11600033__F12 HA/PEI-RH NYPs for UC treatment ENSG00000214285 ENSG00000026508 ENSG00000172936 PMC4422447__F1 Angiotensin II, transforming growth factorB, and Smad signaling pathways PMC5783849__F9 TIPE1 and Wnt/beta‐catenin signalling pathway in gastric cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9150370__F2 Is Arsenic Exposure a Risk Factor for Metabolic Syndrome? A Review of the Potential Mechanisms ENSG00000162711 ENSG00000142082 PMC6374752__F1 Tryptophan-kynurenine pathway and major functional consequences in the context of GBM growth ENSG00000188676 PMC8944478__F6 Identification and Molecular Analysis of m6A-circRNAs from Cashmere Goat Reveal Their Integrated Regulatory Network and Putative Functions in Secondary Hair Follicle during Anagen Stage ENSG00000067141 ENSG00000107562 ENSG00000134982 ENSG00000110931 ENSG00000150093 ENSG00000112715 ENSG00000106546 ENSG00000130164 ENSG00000095739 ENSG00000196914 ENSG00000101333 ENSG00000125266 ENSG00000084093 ENSG00000138795 ENSG00000157764 ENSG00000169439 ENSG00000120693 ENSG00000139926 ENSG00000018408 ENSG00000164171 ENSG00000182621 ENSG00000277641 ENSG00000120910 ENSG00000136603 ENSG00000128710 ENSG00000117020 ENSG00000150672 ENSG00000164093 ENSG00000145349 ENSG00000204217 ENSG00000186469 PMC5831768__F2 Non-canonical Shh signaling in commissural axon guidance ENSG00000164161 ENSG00000063660 ENSG00000144857 ENSG00000164690 ENSG00000128602 PMC3238080__F2 Regulation of intracellular signaling by antiepileptics and modulators of glutamate, acetylcholine, and melatonin systems ENSG00000196531 ENSG00000167658 PMC8831078__F2 Ubiquitination of AMPA receptor subunits ENSG00000108523 ENSG00000134982 ENSG00000072401 ENSG00000109189 PMC11206339__F1 Common synthesis pathway for testosterone from cholesterol and its subsequent conversion into estrogenic and androgenic active metabolites ENSG00000203857 PMC5321522__F1 Clinical imaging of cancer metabolism ENSG00000180210 ENSG00000078237 ENSG00000115419 ENSG00000026103 PMC4134348__F1 Lung cell-specific modulation of LPS-induced TLR4 receptor and adaptor localization ENSG00000136869 ENSG00000150455 PMC8369426__F2 Phytochemicals: Targeting Mitophagy to Treat Metabolic Disorders ENSG00000177169 ENSG00000175193 ENSG00000116688 ENSG00000158828 ENSG00000069509 ENSG00000247077 PMC8010610__F1 RAS Signalling Pathway (90% of JMML cases involve mutations in the RAS pathway): N/KRAS proteins (in Pink) alternate between “ACTIVE” and “INACTIVE” states ENSG00000033327 ENSG00000198793 ENSG00000196712 ENSG00000179295 PMC9535022__F3 Signaling pathways and targeted therapies in lung squamous cell carcinoma: mechanisms and clinical trials ENSG00000168003 ENSG00000079999 PMC9535022__F2 Signaling pathways and targeted therapies in lung squamous cell carcinoma: mechanisms and clinical trials ENSG00000135446 ENSG00000123374 ENSG00000077782 ENSG00000146648 PMC9535022__F4 Signaling pathways and targeted therapies in lung squamous cell carcinoma: mechanisms and clinical trials ENSG00000151376 ENSG00000198793 ENSG00000162521 ENSG00000147548 ENSG00000178691 ENSG00000082212 ENSG00000109670 PMC9535022__F6 Signaling pathways and targeted therapies in lung squamous cell carcinoma: mechanisms and clinical trials ENSG00000169245 ENSG00000105325 ENSG00000135446 ENSG00000138755 ENSG00000121067 ENSG00000164399 PMC6808435__F10 RNA-Seq analysis reveals an essential role of tyrosine metabolism pathway in response to root-rot infection in Gerbera hybrida PMC4511781__F1 Insulin and IGF-1 signaling in gray mouse lemursIR and IGF-IR share a similar signaling pathway which invokes downstream changes in two main branches – the mitogenic pathway (Ras/Raf/MEK/ERK) and the metabolic pathway (PI3K/Akt) ENSG00000169047 ENSG00000198793 ENSG00000140443 PMC6025294__F2A JMY in p53 Regulation ENSG00000149311 ENSG00000152409 ENSG00000023734 PMC6149912__F1 Inhibition of DDR1-BCR signaling by nilotinib ENSG00000186716 ENSG00000177606 ENSG00000136997 ENSG00000026508 ENSG00000168036 PMC5165017__F1 Working Hypothesis of mechanotransduction in EC cells ENSG00000154864 PMC7462039__F2 Engineering Brain-Specific Pericytes from Human Pluripotent Stem Cells ENSG00000170365 ENSG00000170558 ENSG00000168036 ENSG00000112715 PMC7462039__F1 Engineering Brain-Specific Pericytes from Human Pluripotent Stem Cells ENSG00000150907 ENSG00000198793 ENSG00000163914 ENSG00000185591 ENSG00000146648 PMC3933348__F1 Overview of tamoxifen metabolism pathway and the main enzymes involved ENSG00000165841 ENSG00000197408 PMC8664518__F1 Acupuncture for Primary Dysmenorrhea: A Potential Mechanism from an Anti-Inflammatory Perspective ENSG00000162711 ENSG00000142224 PMC6491677__F1 Metacore™ map showing the signaling context of the genes contained in the “Vascular endothelial cell damage in SLE” pathway ENSG00000019991 ENSG00000108691 ENSG00000189403 ENSG00000112715 ENSG00000127191 PMC10743522__F3 The signaling pathways regulated by phase separation during development ENSG00000136997 ENSG00000168036 PMC1087795__F1 Schematic depiction of the S ENSG00000146005 ENSG00000173599 PMC9524038__F2 Runx2 and Nell-1 in dental follicle progenitor cells regulate bone remodeling and tooth eruption ENSG00000134982 ENSG00000168036 PMC3726950__F2 Regulation of autophagy pathways and targets for modulating autophagy by drugs/compounds ENSG00000198793 ENSG00000146648 PMC7915952__F1 Canonical pathway of microRNA (miRNA) processing ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC7225923__F2 Cancer cell dormancy ENSG00000133110 ENSG00000198793 ENSG00000112715 PMC3193409__F4 Expanding role of ubiquitination in protein kinase activation in diverse NFKB pathways ENSG00000149311 ENSG00000183735 ENSG00000088888 ENSG00000157625 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000121060 PMC9520190__F3 Molecular pathogenesis: Connections between viral hepatitis-induced and non-alcoholic steatohepatitis-induced hepatocellular carcinoma ENSG00000169047 ENSG00000140443 PMC7546851__F1 Neutrophils in TME ENSG00000178860 ENSG00000019991 ENSG00000262406 ENSG00000081041 ENSG00000163235 ENSG00000163739 ENSG00000171791 ENSG00000168610 ENSG00000121966 PMC2845723__F2 The bile salt synthetic pathway ENSG00000167910 ENSG00000099377 ENSG00000135929 PMC5069771__F2 Genes upregulated after RSV infection ENSG00000160789 ENSG00000187608 ENSG00000138772 ENSG00000089127 ENSG00000183486 ENSG00000158578 ENSG00000157601 ENSG00000150337 ENSG00000180644 ENSG00000162772 ENSG00000168961 ENSG00000230034 ENSG00000177409 ENSG00000111796 ENSG00000134321 ENSG00000079246 ENSG00000078081 ENSG00000134326 ENSG00000138755 ENSG00000169429 ENSG00000233816 ENSG00000161905 ENSG00000117228 ENSG00000185745 ENSG00000160181 ENSG00000185885 ENSG00000237693 ENSG00000162654 ENSG00000276561 ENSG00000007171 ENSG00000133048 ENSG00000102837 ENSG00000170458 ENSG00000123609 ENSG00000291834 ENSG00000127324 ENSG00000172936 ENSG00000111331 ENSG00000115523 ENSG00000110077 ENSG00000169248 ENSG00000163568 ENSG00000186818 ENSG00000086548 ENSG00000137496 ENSG00000196136 ENSG00000277571 ENSG00000168062 ENSG00000152778 ENSG00000285176 ENSG00000133106 ENSG00000145623 ENSG00000276051 ENSG00000108688 ENSG00000139970 ENSG00000002549 ENSG00000103534 ENSG00000148346 ENSG00000081041 ENSG00000100906 ENSG00000137198 ENSG00000163221 ENSG00000183684 ENSG00000130589 ENSG00000277943 ENSG00000172183 ENSG00000184979 ENSG00000291363 ENSG00000111537 ENSG00000285318 ENSG00000177606 ENSG00000135114 ENSG00000108700 ENSG00000164136 ENSG00000291905 ENSG00000291555 ENSG00000142089 ENSG00000100985 ENSG00000204936 ENSG00000005381 ENSG00000115155 PMC9504325__F1 Host Cell Antimicrobial Responses against Helicobacter pylori Infection: From Biological Aspects to Therapeutic Strategies ENSG00000285433 ENSG00000106100 PMC11906358__F5 Balancing dopamine levels by clock components ENSG00000132326 PMC8426673__F1 Lethal internal face of the coronaviruses: Kidney tropism of the SARS, MERS, and COVID19 viruses ENSG00000130234 PMC11906358__F4 Molecular model of light-induced signalling pathways for clock phase shifting ENSG00000142178 ENSG00000120875 ENSG00000177606 ENSG00000132326 ENSG00000179094 ENSG00000105662 ENSG00000164949 PMC8892088__F1 Metabolic regulation of ferroptosis in the tumor microenvironment ENSG00000168003 ENSG00000151012 ENSG00000167468 PMC5068231__F7 Cpb1–C3–C3aR pathway amplifying p38 MAPK signaling downstream of TLR4 and Ifnar activation in macrophages ENSG00000111537 ENSG00000136869 ENSG00000007171 ENSG00000153002 PMC7385189__F2 Primary resistance ENSG00000169245 ENSG00000089692 ENSG00000163599 ENSG00000198793 ENSG00000138755 ENSG00000168036 ENSG00000169429 ENSG00000198846 ENSG00000273686 ENSG00000146648 PMC8892088__F4 Metabolic regulation of ferroptosis in the tumor microenvironment ENSG00000168003 ENSG00000111537 ENSG00000151012 ENSG00000115415 ENSG00000167468 PMC8892088__F5 Metabolic regulation of ferroptosis in the tumor microenvironment ENSG00000135218 ENSG00000167468 PMC4984446__F1 The importance of ribosome production, and the 5S RNP–MDM2 pathway, in health and disease PMC7465818__F1 Canonical NFKB pathway can be activated via multiple different ligand/receptor interactions ENSG00000104856 ENSG00000186716 PMC3956512__F1 The unfolded protein response (UPR) pathway in Cryptococcus ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC7352466__F2 Biological effect of PARPi on cancer cells ENSG00000169245 ENSG00000183735 ENSG00000164430 PMC3569094__F1 Novel therapeutic approaches for overcoming limitations in the gemcitabine pathway ENSG00000167325 ENSG00000171848 ENSG00000158825 PMC11764055__F2 Mechano-transduction pathways regulating YAP/TAZ activity ENSG00000186575 ENSG00000114978 ENSG00000150457 ENSG00000131023 PMC8334851__F2 Impacts of Immunometabolism on Male Reproduction ENSG00000049768 PMC3331705__F1 Tumor suppressors and oncogenes in the Wnt pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000102312 PMC3701596__F3 Sleep specific effects on protein processing and the unfolded protein response ENSG00000128272 ENSG00000146469 ENSG00000126261 ENSG00000105669 ENSG00000198168 PMC6789122__F7 Proposed model for the role of RarA in adrenocortical development ENSG00000071564 ENSG00000162552 ENSG00000138795 ENSG00000179142 ENSG00000168036 ENSG00000112715 PMC5122440__F2 Sweet trap in tumors: aerobic glycolysis and potential targets for therapy ENSG00000198793 ENSG00000078237 PMC3613825__F8 Proposed model of regulation of pro-apoptotic signaling pathway by miR-128 ENSG00000096717 ENSG00000115461 PMC3775871__F1 Epigenetic Regulation of SOX9 by the NFKB Signaling Pathway in Pancreatic Cancer Stem Cells ENSG00000104856 ENSG00000226275 ENSG00000163235 ENSG00000138798 ENSG00000173039 ENSG00000197943 ENSG00000157625 ENSG00000150455 PMC3636549__F2 HEDGEHOG SIGNALING IN CHOLANGIOCYTES ENSG00000164161 ENSG00000128602 PMC4746688__F8 A Novel Pathway for Triacylglycerol Biosynthesis Is Responsible for the Accumulation of Massive Quantities of Glycerolipids in the Surface Wax of Bayberry (Myrica pensylvanica) Fruit ENSG00000171759 ENSG00000198670 PMC9534503__F6 Species unique MEGENA modules ENSG00000182481 ENSG00000114346 ENSG00000169682 ENSG00000101057 ENSG00000108828 ENSG00000112039 ENSG00000273686 ENSG00000146192 ENSG00000065328 ENSG00000168268 ENSG00000033030 ENSG00000166887 ENSG00000160051 ENSG00000188739 ENSG00000163131 ENSG00000276051 ENSG00000204673 PMC6534790__F2 Coagulation factors and their connection to monocyte activation ENSG00000180210 ENSG00000110799 PMC7230958__F1 Summary of the metabolic pathway for n-6 and n-3 polyunsaturated fatty acids ENSG00000196839 PMC11769975__F2 Fusobacterium nucleatum reshapes the tumor milieu in CRC cells and immune cells [This figure was created using MedPeer (www ENSG00000081041 ENSG00000181847 ENSG00000138798 ENSG00000118520 PMC11769975__F1 Mechanisms by which Fusobacterium nucleatum may contribute to colorectal carcinogenesis [This figure was created using MedPeer (www ENSG00000154764 ENSG00000188064 ENSG00000149269 ENSG00000136997 ENSG00000168036 ENSG00000172936 ENSG00000136869 PMC6337850__F6 A working model: N-Myc differentially regulating miR-421/ATM pathway contributes to ADT resistance and Enzalutamide resistance development of prostate cancer ENSG00000149311 ENSG00000105656 PMC6823248__F5 HDAC6 inhibition repressed B cell signaling pathways in NZB/NZW mice ENSG00000095585 ENSG00000070190 ENSG00000010810 ENSG00000177606 ENSG00000110651 ENSG00000113520 ENSG00000136869 ENSG00000134061 PMC9687725__F6 Comparative Transcriptomics and Proteomics of Cancer Cell Lines Cultivated by Physiological and Commercial Media ENSG00000111837 ENSG00000127022 PMC5733345__F1 Principal pathways of cell death ENSG00000002330 ENSG00000137275 ENSG00000125538 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC12204001__F1 Molecular mechanisms of cGAS-STING pathway activation ENSG00000183735 ENSG00000164430 PMC11769975__F5 Apoptotic effect and immune invasion of Porphyromonas gingivalis in OSCC [This figure was created using MedPeer (www ENSG00000162711 ENSG00000002330 ENSG00000168610 PMC12204001__F3 Protumor role of cGAS-STING pathway ENSG00000183735 ENSG00000164430 PMC4139969__F3 Role and targeting of Aurora kinases in head and neck cancer ENSG00000129474 ENSG00000111581 ENSG00000071655 ENSG00000100906 ENSG00000178999 ENSG00000037474 ENSG00000087586 ENSG00000291938 ENSG00000160783 ENSG00000086827 ENSG00000012048 ENSG00000138778 ENSG00000163516 ENSG00000149269 ENSG00000112640 ENSG00000074054 ENSG00000196116 PMC12204001__F2 Anti-tumor role of cGAS-STING pathway ENSG00000169248 ENSG00000169245 ENSG00000164430 ENSG00000231179 ENSG00000204520 ENSG00000159335 PMC11769975__F3 Possible molecular mechanisms of Fusobacterium nucleatum in tumor progression [This figure was created using MedPeer (www ENSG00000023445 ENSG00000162711 ENSG00000168036 ENSG00000136869 PMC8460903__F5 Mechanotransduction Regulates Reprogramming Enhancement in Adherent 3D Keratocyte Cultures ENSG00000170365 ENSG00000163914 PMC3750319__F2 Canonical, non-canonical and the atypical NFKB signaling pathway ENSG00000149311 PMC8502110__F5 MiR-361-5p/abca1 and MiR-196-5p/arhgef12 Axis Involved in Gamma-Sitosterol Inducing Dual Anti-Proliferative Effects on Bronchial Epithelial Cells of Chronic Obstructive Pulmonary Disease ENSG00000060982 ENSG00000198793 ENSG00000196914 PMC9687725__F3 Comparative Transcriptomics and Proteomics of Cancer Cell Lines Cultivated by Physiological and Commercial Media ENSG00000125414 PMC8647069__F8 COVID-19 with obliterating endothelialitis associated with complement activation and accumulation of C5aR1-expressing macrophages around vessels ENSG00000177575 ENSG00000130234 ENSG00000129226 PMC9687725__F2 Comparative Transcriptomics and Proteomics of Cancer Cell Lines Cultivated by Physiological and Commercial Media ENSG00000159224 ENSG00000138798 ENSG00000176533 ENSG00000174946 ENSG00000100985 ENSG00000126458 PMC3750319__F5 Crosstalk of the canonical NFKB pathway with other signaling processes ENSG00000157554 ENSG00000173039 ENSG00000083799 ENSG00000162692 ENSG00000168610 PMC2772702__F6 The PI3k/Akt signaling pathway depicting the possible sites of action by the PI3k inhibitors LY294002 and wortmannin and the Akt inhibitors Akt-VIII, Akt-V, and Akt-IV ENSG00000198793 ENSG00000166278 PMC5908099__F4 Signalling interaction of the death receptor pathway and mitochondrial pathway ENSG00000108582 ENSG00000100504 PMC7958858__F2 Signaling pathways involved in TJ formation and modulation ENSG00000170458 ENSG00000173039 ENSG00000175104 ENSG00000146648 ENSG00000184216 PMC8285369__F1 Melatonin interferes with COVID-19 at several distinct ROS-related steps ENSG00000005381 PMC4450212__F4 Significant signaling pathway networks mined from phosphotyrosine-containing proteins in a glioblastoma tissue ENSG00000213614 ENSG00000107521 ENSG00000074800 ENSG00000183808 ENSG00000105991 ENSG00000132294 ENSG00000064886 ENSG00000166073 ENSG00000130695 ENSG00000158792 ENSG00000059769 ENSG00000166800 ENSG00000165799 ENSG00000100558 ENSG00000166341 ENSG00000172794 ENSG00000101639 ENSG00000291941 ENSG00000176894 ENSG00000004399 ENSG00000156011 ENSG00000186635 ENSG00000196437 ENSG00000105426 ENSG00000169067 PMC11865073__F5 Neuroinflammation signaling pathway activity and member DEGs from mThy1-Alpha-synuclein overexpression at 10 months ENSG00000243414 ENSG00000168329 ENSG00000011600 ENSG00000169562 ENSG00000168036 ENSG00000171791 ENSG00000150455 ENSG00000125084 ENSG00000157240 ENSG00000150782 ENSG00000183735 ENSG00000103490 ENSG00000113520 ENSG00000189403 ENSG00000119912 ENSG00000090376 ENSG00000115594 ENSG00000026103 ENSG00000023445 ENSG00000073756 ENSG00000185652 ENSG00000108691 ENSG00000111537 ENSG00000172936 ENSG00000100985 ENSG00000114739 PMC6381083__F9 Canonical and non-canonical NFKB pathway ENSG00000104856 ENSG00000173039 ENSG00000172936 ENSG00000111321 ENSG00000131323 ENSG00000127191 PMC11865073__F3 Neuroinflammation signaling pathway activity and member DEGs from mThy1-Alpha-synuclein overexpression at 7 months ENSG00000145864 ENSG00000243414 ENSG00000168329 ENSG00000107562 ENSG00000169562 ENSG00000168036 ENSG00000171791 ENSG00000125084 ENSG00000150782 ENSG00000103490 ENSG00000149968 ENSG00000113520 ENSG00000189403 ENSG00000135503 ENSG00000119912 ENSG00000116044 ENSG00000073756 ENSG00000132693 ENSG00000276561 ENSG00000169245 ENSG00000185652 ENSG00000108691 ENSG00000111537 ENSG00000146592 ENSG00000131323 ENSG00000100985 ENSG00000132164 PMC6162708__F1 Canonical and DNA damage-induced NFKB signalling pathways ENSG00000095585 ENSG00000149311 ENSG00000175054 ENSG00000291603 ENSG00000102871 ENSG00000186716 ENSG00000175104 PMC3575708__F8 Model for Ctip2 functions in the proliferation and differentiation of epidermal keratinocytes ENSG00000148400 ENSG00000138798 ENSG00000146648 PMC2574996__F15 Our difficulty in suppressing epimerization at the bis-benzylic stereocenter bearing the ester in the azide displacement led us to pursue an alternate route to amurensinine via intermediates with attenuated acidity at the bis-benzylic carbon () ENSG00000149311 ENSG00000062485 PMC2574996__F12 We then examined the Pd-catalyzed oxidative kinetic resolution of hydroxyester (±)-15 ENSG00000149311 ENSG00000062485 PMC4754450__F1 Abbreviated pathway for the biosynthesis and metabolism of Orn in plants in connection to polyamines, amino acids, TCA cycle metabolites, and alkaloids ENSG00000124357 ENSG00000036473 ENSG00000100033 PMC7310007__F2 cGAS-STING pathway ENSG00000183735 ENSG00000164430 PMC11121637__F1 Schematic representation illustrates the role of miRNAs in the regulation of FOSL1 ENSG00000175592 PMC2948329__F2 TSC1/2 integrates multiple signals to control cell growth and proliferation ENSG00000123374 PMC11121637__F4 FOSL1 in promoting drug resistance and radio resistance ENSG00000175592 ENSG00000164086 PMC5989100__F2 Major signalling pathways involved in the control of skeletal muscle hypertrophy and mitochondrial biogenesis ENSG00000198793 PMC4848843__F2 Regulation of lipid metabolism by BAF60a and BAF60c in periportal and perivenous hepatocytes, respectively, under the control of nutritional and hormonal signals ENSG00000096717 ENSG00000026103 PMC7330533__F2 Network pharmacology of targets of anemoside B4 against pneumonia ENSG00000132906 ENSG00000105329 ENSG00000109320 ENSG00000064012 ENSG00000164305 PMC7330533__F8 Schematic of anemoside B4’s anti-inflammatory mechanism ENSG00000172936 ENSG00000136869 PMC8120178__F2 Phytochemicals in Chemoprevention: A Cost-Effective Complementary Approach ENSG00000002330 ENSG00000198793 PMC10669348__F3 Schematic and simplified overview of the intracellular transduction cascades induced by 5-HT2AR TrkB and Sig-1R receptor activation by psychedelics ENSG00000198793 PMC8661100__F3 Evidence of myomiR regulation of the pentose phosphate pathway during mechanical load‐induced hypertrophy ENSG00000284320 ENSG00000065911 ENSG00000100714 ENSG00000092621 ENSG00000164466 ENSG00000135069 ENSG00000111371 ENSG00000146733 PMC10142331__F2 SFTSV mediates cell cycle, apoptosis, and the cGAS-STING pathway to achieve immune escape ENSG00000183735 ENSG00000164430 PMC10142331__F1 Mechanisms by which SFTS inhibits key immune signalling pathways and promotes inflammation ENSG00000132109 ENSG00000162711 ENSG00000213928 ENSG00000088888 ENSG00000121060 ENSG00000276561 PMC4499842__F7 UCB-MSC therapy is curative for IC bladder ENSG00000138798 ENSG00000196468 PMC11606877__F3 Anticancer role of RES against NMSC: Focusing on oxidative stress, cellular, and molecular mechanisms ENSG00000168036 PMC8617551__F2 Antagonism of interferon signalling by SARS-CoV-2 and related coronaviruses ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000177606 ENSG00000135828 ENSG00000175104 ENSG00000121060 ENSG00000276561 ENSG00000142166 PMC7299535__F7 Increased CHST15 follows decline in arylsulfatase B (ARSB) and disinhibition of non-canonical WNT signaling: potential impact on epithelial and mesenchymal identity ENSG00000050165 ENSG00000107485 PMC6005202__F2 Towards a sustainable bio-based economy: Redirecting primary metabolism to new products with plant synthetic biology ENSG00000039537 PMC4442140__F3 Results from validation screens for Listeria infection ENSG00000140564 ENSG00000147202 ENSG00000070831 ENSG00000163519 ENSG00000182899 ENSG00000198793 ENSG00000150093 ENSG00000061676 ENSG00000196586 ENSG00000111737 ENSG00000182541 ENSG00000106683 ENSG00000131089 ENSG00000196923 ENSG00000136997 ENSG00000084733 ENSG00000184432 ENSG00000149806 ENSG00000115091 ENSG00000124102 ENSG00000101282 ENSG00000146469 ENSG00000288461 ENSG00000161016 ENSG00000110395 ENSG00000122705 ENSG00000112378 ENSG00000137076 ENSG00000141367 PMC3635523__F7 Schematic model put forward the potential role of P4HB at different GBM cell states to TMZ treatment ENSG00000128272 ENSG00000144895 PMC9589302__F6 Inhibition of IRAK 1/4 alleviates colitis by inhibiting TLR 4/NFKB pathway and protecting the intestinal barrier ENSG00000136869 ENSG00000184216 PMC5850280__F1 Wnt activity is necessary for heart development and becomes very low in the adult heart ENSG00000178860 ENSG00000156076 ENSG00000168036 PMC9107641__F2 Metabolic engineering of Clostridium ljungdahlii for the production of hexanol and butanol from CO2 and H2 ENSG00000100473 ENSG00000060339 ENSG00000127948 PMC6984455__F1 Brief mechanisms of Ub-dependent and Ub-independent mitophagy ENSG00000099968 PMC4550852__F7 FABP4 reversed the regulation of leptin on mitochondrial fatty acid oxidation in mice adipocytes ENSG00000198793 ENSG00000138356 PMC3023586__F1 Host-cell signalling induced by EPEC Tir ENSG00000010810 ENSG00000135605 PMC9021824__F5 miR-1908 Dysregulation in Human Cancers ENSG00000157933 ENSG00000130164 PMC9021824__F2 miR-1908 Dysregulation in Human Cancers ENSG00000130522 ENSG00000168256 ENSG00000081189 PMC1951772__F8 PI3K activation by eIF2A kinases ENSG00000144895 ENSG00000198793 ENSG00000164327 PMC7217141__F2 Summary of the processes thought to be involved in thoracic aortopathy development ENSG00000291748 ENSG00000185532 ENSG00000166147 PMC3490280__F2 Recipient T-lymphocytes govern Mesenchymal stem cell (MSC)-based bone regeneration via IFNG and TNFA ENSG00000178860 ENSG00000137834 ENSG00000026103 PMC7912581__F8 Complex mechanism of FASIS and (B) GPR40 receptor part ENSG00000159224 ENSG00000042832 ENSG00000167323 ENSG00000146469 ENSG00000086991 ENSG00000131096 ENSG00000142082 ENSG00000147262 ENSG00000144935 ENSG00000293604 ENSG00000070985 ENSG00000138741 ENSG00000174611 PMC4893201__F1 Interplay between metabolism and epigenetics: a nuclear adaptation to environmental changes ENSG00000105835 ENSG00000077463 ENSG00000096717 PMC2543934__F5 PPARG in Type 1/Type 2 T (NK) cell differentiation ENSG00000159128 ENSG00000138378 ENSG00000115415 ENSG00000107485 ENSG00000113520 PMC11669335__F3 Canonical and non-canonical inflammasome pathways in pyroptosis ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC5440090__F2 Anti-tumor immune response through CTLA-4 and PD-1 pathway blockade, and T-cell signaling in the treatment of melanoma ENSG00000168502 PMC11669335__F2 Extrinsic and intrinsic apoptotic pathways ENSG00000120868 ENSG00000168040 PMC7117992__F2 Key longevity-regulating pathway proteins whose functions may be altered or enhanced by differential PTMs/proteoforms in long-lived species ENSG00000143799 ENSG00000171105 ENSG00000198793 ENSG00000077463 ENSG00000096717 ENSG00000057663 PMC9315936__F4 JAK2 Alterations in Acute Lymphoblastic Leukemia: Molecular Insights for Superior Precision Medicine Strategies ENSG00000145777 ENSG00000292363 PMC7912581__F2 New paradigm in the mechanism of GSIS in the context of the regulation of insulin secretion ENSG00000159224 ENSG00000167323 ENSG00000146469 ENSG00000086991 ENSG00000131096 ENSG00000157005 ENSG00000132639 ENSG00000065833 ENSG00000144935 ENSG00000293604 ENSG00000173599 ENSG00000070985 ENSG00000174611 PMC8923340__F3 COVID-19 pandemic: the delta variant, T-cell responses, and the efficacy of developing vaccines ENSG00000140564 ENSG00000276561 ENSG00000183735 ENSG00000130234 ENSG00000138755 ENSG00000184012 ENSG00000169429 ENSG00000172936 ENSG00000107201 ENSG00000131323 ENSG00000175104 ENSG00000090376 ENSG00000164342 PMC7829997__F2 Altered Gut Microbial Metabolites in Amnestic Mild Cognitive Impairment and Alzheimer’s Disease: Signals in Host–Microbe Interplay ENSG00000106546 PMC11669335__F5 Classical autophagy pathway ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000144848 ENSG00000145782 PMC11669335__F4 Necroptosis pathway ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC3778193__F6 Notch1 promotes the pro-osteogenic response of human aortic valve interstitial cells via modulation of ERK1/2 and NFKB activation ENSG00000148400 ENSG00000136869 PMC8471547__F6 SMAD4 Feedback Activates the Canonical TGFB Family Signaling Pathways ENSG00000185591 ENSG00000135503 ENSG00000204217 PMC3141288__F3 Roles of NFKB-mediated inflammatory pathway in cellular transformation, cancer survival, proliferation, invasion, angiogenesis and metastasis ENSG00000162692 ENSG00000121966 PMC3691323__F6 Role of Helicase-Like Transcription Factor (Hltf) in the G2/M Transition and Apoptosis in Brain ENSG00000134982 ENSG00000105127 ENSG00000149503 PMC8431051__F2 Somatic Mutations on the Immune Response of the Tumor Microenvironment in Prostate Cancer ENSG00000157554 ENSG00000108691 ENSG00000154059 ENSG00000184371 ENSG00000169429 ENSG00000049768 PMC8238692__F1 Periodontitis Exacerbates and Promotes the Progression of Chronic Kidney Disease Through Oral Flora, Cytokines, and Oxidative Stress ENSG00000167207 ENSG00000168036 ENSG00000136869 ENSG00000121966 PMC7779530__F2 TGFB signaling PMC6161786__F2 Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy ENSG00000175104 ENSG00000184216 PMC6721808__F7 Simplified model of fatty acid (FA) metabolism ENSG00000135218 ENSG00000169710 ENSG00000140464 PMC4977549__F1 ‘Atherothrombosis-associated microRNAs in Antiphospholipid syndrome and Systemic Lupus Erythematosus patients’ ENSG00000162889 ENSG00000230930 ENSG00000140564 ENSG00000259207 ENSG00000164761 ENSG00000173039 ENSG00000213341 ENSG00000171791 ENSG00000166484 ENSG00000121807 ENSG00000168610 ENSG00000087460 ENSG00000180210 ENSG00000065135 ENSG00000110395 ENSG00000115415 ENSG00000134070 ENSG00000136869 ENSG00000172936 ENSG00000131196 PMC11831195__F3 Molecular docking of PD and targets ENSG00000149968 ENSG00000073756 ENSG00000168610 PMC6721808__F1 Simplified scheme of the cellular metabolism pathways important for AML pathophysiology ENSG00000198793 ENSG00000166278 ENSG00000103257 PMC7281175__F2 Metabolic pathways in hepatocarcinogenesis ENSG00000131473 ENSG00000042832 ENSG00000276559 ENSG00000172893 ENSG00000167468 ENSG00000113161 ENSG00000180432 ENSG00000099377 ENSG00000167508 ENSG00000135929 PMC11591849__F3 The diverse mechanisms through which anti-diabetic pharmacotherapy may affect tumor microenvironment dynamics ENSG00000169245 ENSG00000162711 ENSG00000108691 ENSG00000169429 ENSG00000168610 PMC11591849__F1 Impact of metformin on cancer-related signaling pathways via AMPK activation ENSG00000177169 ENSG00000169047 ENSG00000198793 ENSG00000140443 PMC8263695__F1 Targeting the eicosanoid pathway in hepatocellular carcinoma PMC10389832__F1 CGAS-STING in Age-Related Diseases from Mechanisms to Therapies ENSG00000183735 ENSG00000164430 PMC6141902__F1 The two commonly activated pathways and genetic aberrations involved in thyroid cancer, as well as the targeted therapies studied in thyroid cancer ENSG00000198793 ENSG00000164362 ENSG00000146648 ENSG00000196712 PMC8382522__F9 Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/Beta-Catenin Signaling Pathway ENSG00000134982 ENSG00000125538 ENSG00000168036 PMC7177281__F1 Neurotrophins and their effect on angiogenesis and neurogenesis in the skin ENSG00000197081 ENSG00000138798 ENSG00000146648 ENSG00000140443 PMC10389832__F4 CGAS-STING in Age-Related Diseases from Mechanisms to Therapies ENSG00000143799 ENSG00000197594 ENSG00000168610 PMC7729630__F5 Schematic model illustrating an effect of PEA on CORT-induced depression-like mice model ENSG00000146399 ENSG00000102003 PMC6836709__F9 Pathways to autoimmunity and autoinflammation in ABIN1[D485N] mice ENSG00000172936 ENSG00000167900 ENSG00000184216 PMC5855695__F1 MicroRNA biosynthesis pathway ENSG00000092847 ENSG00000128191 ENSG00000113360 ENSG00000134698 ENSG00000123908 PMC6292306__F2 Serotonin directly increases PTHrP synthesis in the mammary gland and indirectly through regulation of the Hedgehog signaling pathway ENSG00000293604 ENSG00000164690 ENSG00000036828 PMC4671741__F5 Profiling the role of mammalian target of rapamycin in the vascular smooth muscle metabolome in pulmonary arterial hypertension ENSG00000141086 ENSG00000171759 ENSG00000116984 PMC6292306__F1 Calcium movement into the mammary gland regulates maternal calcium homeostasis during lactation ENSG00000293604 ENSG00000036828 PMC8593415__F8 Multidimensional Mutational Profiling of the Indian HNSCC Sub-Population Provides IRAK1, a Novel Driver Gene and Potential Druggable Target ENSG00000203867 ENSG00000092054 ENSG00000198793 ENSG00000116830 ENSG00000166407 ENSG00000133818 PMC3731598__F1 An immune synapse and downstream events ENSG00000139193 ENSG00000089692 ENSG00000163599 PMC11352355__F2 Cell functions of K6, K16, and K17 ENSG00000188486 ENSG00000198830 ENSG00000111537 ENSG00000160224 ENSG00000115415 ENSG00000198793 ENSG00000168610 ENSG00000146648 ENSG00000186832 PMC11040904__F2 Regulatory pathways governing PD-L1 via phosphorylation and ubiquitination ENSG00000091317 ENSG00000103266 ENSG00000183723 ENSG00000134982 ENSG00000134910 ENSG00000138798 ENSG00000036672 ENSG00000185745 ENSG00000121067 ENSG00000086758 ENSG00000101695 ENSG00000197530 ENSG00000118503 ENSG00000135446 ENSG00000105810 ENSG00000064012 PMC11040904__F4 Regulatory pathways of PD-L1 via deubiquitination ENSG00000184979 ENSG00000223573 ENSG00000124422 ENSG00000136878 ENSG00000134982 ENSG00000036672 ENSG00000247746 PMC11040904__F3 Negative regulatory pathways of PD-L1 mediated by other posttranslational modifications ENSG00000137673 ENSG00000187608 ENSG00000014123 ENSG00000134982 ENSG00000120686 ENSG00000111653 ENSG00000100985 ENSG00000145391 PMC3831322__F5 Scheme illustrating potential mechanisms by which nandrolone reduces bone loss after SCI ENSG00000154342 ENSG00000163251 ENSG00000162337 PMC11040904__F6 Positive regulatory pathways of PD-L1 mediated by other posttranslational modifications ENSG00000065485 ENSG00000188706 ENSG00000134982 ENSG00000138798 ENSG00000196591 ENSG00000169710 ENSG00000165527 ENSG00000163812 PMC11040904__F5 Emerging therapeutic frontiers in cancer: insights into posttranslational modifications of PD-1/PD-L1 and regulatory pathways ENSG00000134982 ENSG00000134910 ENSG00000138798 ENSG00000132432 ENSG00000168036 ENSG00000179913 ENSG00000151948 PMC5403977__F12 EGF and GLP-2 signaling to attenuate mucosal atrophy in a mouse TPN model ENSG00000138798 PMC11040904__F7 Posttranslational modification of PD-1 ENSG00000114737 PMC8960869__F8 Mechanism by which HORMAD1 functions to promote the malignant phenotypes of lung cancer cells ENSG00000138795 ENSG00000137673 ENSG00000134982 ENSG00000168036 ENSG00000100985 PMC6600647__F4 Uncovering the assembly pathway of human ribosomes and its emerging links to disease ENSG00000179041 PMC9504097__F2 Significance of Gut Microbiota and Short-Chain Fatty Acids in Heart Failure ENSG00000162711 ENSG00000150782 ENSG00000277401 PMC3820966__F1 Cellular response to oxidative stress mediating by Beta-adrenergic response and sirtuins involvement ENSG00000116717 PMC9266407__F3 Evaluation of Adverse Effects of Resorbable Hyaluronic Acid Fillers: Determination of Macrophage Responses ENSG00000100473 ENSG00000176248 ENSG00000136997 PMC11586797__F1 Mammalian target of rapamycin signaling pathway and its interaction with EZH2 expression in hepatocellular carcinoma: Mechanisms and implications ENSG00000198793 PMC7859916__F2 Role of Eps8 in the regulation of the malignant phenotype of a tumour ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC3783819__F3 Pathogenesis of RON receptor tyrosine kinase in cancer cells: activation mechanism, functional crosstalk, and signaling addiction ENSG00000019991 ENSG00000087245 ENSG00000033327 ENSG00000163739 ENSG00000138798 ENSG00000136997 ENSG00000173039 ENSG00000026508 ENSG00000168036 ENSG00000168610 ENSG00000146648 ENSG00000140443 PMC3783819__F2 Pathogenesis of RON receptor tyrosine kinase in cancer cells: activation mechanism, functional crosstalk, and signaling addiction ENSG00000198793 ENSG00000177606 PMC9238060__F2 Epigenetic modifications in drug resistance and treatment of breast cancer ENSG00000151376 ENSG00000139372 PMC9238060__F1 Epigenetic modifications in drug resistance and treatment of breast cancer ENSG00000134982 ENSG00000168036 ENSG00000146648 PMC6299639__F2 Mechanism of HSV evades host immune responses ENSG00000183735 ENSG00000088888 ENSG00000144895 ENSG00000115415 ENSG00000163565 ENSG00000172936 ENSG00000131323 ENSG00000135828 ENSG00000175104 ENSG00000164342 PMC7585181__F2 Participation of SUMOylation in molecular signalling pathways involved in atherosclerosis ENSG00000163904 ENSG00000173039 PMC8397972__F4 Convergent Functional Genomics Analysis to Identify Biological Regulators Mediating Effects of Creatine Supplementation ENSG00000124102 ENSG00000001167 ENSG00000143867 ENSG00000198793 ENSG00000136997 ENSG00000115020 ENSG00000185591 ENSG00000265972 ENSG00000178691 PMC3736728__F2 Folate, Alcohol, and Liver Disease PMC11640331__F1 Radiation, Immunotherapy, and Chemotherapy in the Management of Locally Advanced or Metastatic Cutaneous Malignancies ENSG00000106571 ENSG00000128602 PMC6829497__F1 Canonical Wnt ligands induce two mutually exclusive Dvl2- and Fyn-dependent arms ENSG00000154342 ENSG00000281324 ENSG00000162337 ENSG00000291971 ENSG00000168610 PMC6274068__F1 Capsaicin mediates saliva secretion via transient receptor potential vanilloid subtype 1 (TRPV1) ENSG00000161798 ENSG00000196689 PMC8951683__F9 Effect of mitochondrial fusion on chondrogenic differentiation of cartilage progenitor/stem cells via Notch2 signal pathway ENSG00000125398 ENSG00000157766 ENSG00000168036 ENSG00000114315 ENSG00000102172 PMC8649804__F7 Flavonoids: Classification, Function, and Molecular Mechanisms Involved in Bone Remodelling ENSG00000170365 PMC11941340__F1 Interaction of the WNT pathway, Hippo pathway, and Notch pathway ENSG00000113645 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000197905 ENSG00000168036 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000151718 ENSG00000074219 ENSG00000047644 ENSG00000198125 PMC8066746__F3 Schematic model of “Common Pathways Underlying Drug dependence” is an output (FDR p < 0.01) of the Wikipathway functional pathway analysis ENSG00000276825 ENSG00000164742 ENSG00000184845 ENSG00000152495 ENSG00000125675 ENSG00000166501 ENSG00000165059 ENSG00000120251 ENSG00000149295 PMC6204183__F3 Neuropeptide signalling pathway (GO:0007218) enriched by genes that showed higher expression level in the hypothalamus of 3-week-old than 6-week-old cockerels ENSG00000291972 ENSG00000291631 ENSG00000115138 ENSG00000183395 PMC7771963__F1 Interconversion of phosphoinositides in eukaryotic cells ENSG00000112367 ENSG00000124102 ENSG00000148384 PMC3092273__F1 Complementary signaling pathways activated in human cancer cells ENSG00000198793 ENSG00000136997 PMC11669362__F6 Activation profile of the Growth hormone signaling pathway (gene expression via SRF, ELK1, STAT5B, CEBPD, STAT1, STAT3) in the experimental NSCLC groups of RECIST responders (A) and non-responders (B) to PD(L)1 ICI immunotherapy ENSG00000112964 ENSG00000172216 ENSG00000169047 PMC4778065__F9 Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases ENSG00000108840 PMC11669362__F8 Activation profile of the Interleukin 10 signaling pathway in the experimental NSCLC groups of RECIST responders (A) and non-responders (B) to PD(L)1 ICI immunotherapy ENSG00000116001 ENSG00000128016 ENSG00000105397 ENSG00000170458 ENSG00000136869 PMC2907165__F1 Type I IFN Signaling ENSG00000213928 ENSG00000105397 ENSG00000169047 ENSG00000198793 ENSG00000099942 ENSG00000141968 ENSG00000142166 PMC10820555__F3 Study on the Pharmacological Mechanism of Icariin for the Treatment of Alzheimer’s Disease Based on Network Pharmacology and Molecular Docking Techniques ENSG00000100290 ENSG00000072274 ENSG00000136869 ENSG00000168610 PMC5783486__F4 Network of differentially expressed proteins in KD with CAD and CAA ENSG00000261701 ENSG00000113889 ENSG00000113600 ENSG00000000971 ENSG00000244731 ENSG00000120885 ENSG00000115718 ENSG00000122194 ENSG00000236625 ENSG00000163631 ENSG00000180210 ENSG00000113905 ENSG00000291998 ENSG00000117601 ENSG00000175899 ENSG00000100979 ENSG00000198670 ENSG00000158874 ENSG00000122862 ENSG00000171560 ENSG00000165471 PMC6322547__F1 Transcriptomic analysis of axon guidance signaling pathways in liver fibrogenesis ENSG00000107562 ENSG00000145147 ENSG00000137601 ENSG00000070831 ENSG00000173156 ENSG00000288455 ENSG00000113456 ENSG00000182511 ENSG00000172602 ENSG00000144857 ENSG00000010810 ENSG00000164690 ENSG00000128602 ENSG00000185008 PMC3430210__F1 TRAIL signaling pathway and mechanisms of TRAIL resistance ENSG00000168040 PMC7458154__F2 Three Examples of Metabolic Transitions Influencing the Activation of Transcriptional Programs That Have an Instrumental Effect on Cell Fate Transitions ENSG00000168036 PMC7397164__F1 Canonical and non-canonical Wnt signaling pathways ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000100592 ENSG00000134982 PMC7458154__F1 Connections of Metabolic Pathways with PTM Reactions through Intermediate Metabolites and Impact of Growth Factor Signaling on Modulation of Glucose Metabolism ENSG00000150907 ENSG00000136997 PMC8232639__F1 Insulin in Health and Disease: An Update ENSG00000002330 PMC7817532__F2 Toxoplasma and Eimeria co-opt the host cFos expression for intracellular development in mammalian cells ENSG00000163399 ENSG00000106571 ENSG00000146592 ENSG00000125675 ENSG00000070961 ENSG00000163914 ENSG00000177606 ENSG00000157017 ENSG00000001626 ENSG00000145349 ENSG00000133818 PMC5035631__F1 Sweet path to metabolic demise: fructose and lipid synthesis ENSG00000262785 ENSG00000138823 ENSG00000138030 ENSG00000111713 ENSG00000169710 ENSG00000136872 PMC1952636__F9 Beta-Arrestin–mediated B1-adrenergic receptor transactivation of the EGFR confers cardioprotection ENSG00000291971 ENSG00000113070 ENSG00000146648 PMC5452883__F1 Intratumoral synthesis of E2 and its inactivation by sulfate conjugation from circulating steroid hormone precursors in cancer cells ENSG00000086696 ENSG00000108786 PMC6959903__F6 MiRNA-mRNA regulatory networks in adenoid cystic carcinoma (ACC) ENSG00000117724 ENSG00000131747 PMC8714803__F7 Differential Co-Expression Network Analysis Reveals Key Hub-High Traffic Genes as Potential Therapeutic Targets for COVID-19 Pandemic ENSG00000164151 ENSG00000135439 ENSG00000130758 ENSG00000105726 ENSG00000177606 ENSG00000103222 ENSG00000104973 ENSG00000169710 ENSG00000102977 ENSG00000061938 PMC8832142__F1 Interaction Between Intracellular Energy Metabolism and Signaling Pathways During Osteogenesis ENSG00000152266 ENSG00000134086 ENSG00000115419 PMC8832142__F2 Interaction Between Intracellular Energy Metabolism and Signaling Pathways During Osteogenesis ENSG00000147162 ENSG00000198408 ENSG00000198793 ENSG00000168036 ENSG00000115419 PMC3557298__F4 mRNA-seq Analysis of the Gossypium arboreum transcriptome Reveals Tissue Selective Signaling in Response to Water Stress during Seedling Stage ENSG00000110934 ENSG00000221818 PMC3994912__F2 Can Transcriptomics Provide Insight into the Chemopreventive Mechanisms of Complex Mixtures of Phytochemicals in Humans? ENSG00000140992 ENSG00000111537 ENSG00000128272 ENSG00000135903 ENSG00000136869 ENSG00000131323 ENSG00000116030 ENSG00000168040 ENSG00000175104 ENSG00000127191 ENSG00000127666 ENSG00000104081 PMC7662794__F1 Risk factors/loci and associated cellular processes identified by genome wide association studies (GWAS) involved in Alzheimer’s Disease (AD) converge to the proteostasis network ENSG00000284816 ENSG00000142192 ENSG00000143801 ENSG00000203710 ENSG00000120885 ENSG00000073921 ENSG00000137845 ENSG00000137642 PMC3104565__F1 Simplified diagrams for agrin-induced signaling ENSG00000134569 ENSG00000010810 ENSG00000030304 PMC6235774__F1 Signaling reactions induced by thrombopoietin ENSG00000090534 ENSG00000291507 ENSG00000157764 ENSG00000117400 ENSG00000198793 ENSG00000135605 ENSG00000127948 PMC3838875__F4 Cancer Cells Incorporate and Remodel Exogenous Palmitate into Structural and Oncogenic Signaling Lipids ENSG00000173599 ENSG00000198670 PMC2613484__F3 Targeting lymphocyte activation through the lymphotoxin and LIGHT pathways ENSG00000104856 ENSG00000111321 ENSG00000162692 PMC4972037__F1 Understanding Extranuclear (Nongenomic) Androgen Signaling: What a frog oocyte can tell us about human biology ENSG00000172680 ENSG00000291971 ENSG00000146648 ENSG00000141456 PMC1937523__F3 Comparison between the gene expression profiles and predicted substrate uptake rates ENSG00000159224 ENSG00000122966 ENSG00000197487 ENSG00000172005 ENSG00000150787 ENSG00000091140 PMC8605121__F2 Dysfunction of miR‐802 in tumors ENSG00000112210 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000128602 ENSG00000077782 ENSG00000146648 ENSG00000132341 PMC8605121__F1 Dysfunction of miR‐802 in tumors ENSG00000007944 ENSG00000128989 ENSG00000198793 ENSG00000170558 ENSG00000020633 ENSG00000065559 ENSG00000168036 ENSG00000196628 ENSG00000140807 ENSG00000112210 ENSG00000157741 ENSG00000154485 ENSG00000173599 ENSG00000145741 ENSG00000145321 ENSG00000083799 ENSG00000111786 ENSG00000132341 PMC6469084__F7 Relationship between USP6NL and the pathway ENSG00000168036 ENSG00000148429 PMC2613484__F7 Targeting lymphocyte activation through the lymphotoxin and LIGHT pathways ENSG00000104856 ENSG00000111321 PMC8551324__F8 NRIP1 is activated by C-JUN/C-FOS and activates the expression of PGR, ESR1 and CCND1 in luminal A breast cancer ENSG00000108557 ENSG00000065361 ENSG00000113070 ENSG00000168036 ENSG00000123374 ENSG00000168610 ENSG00000146648 PMC10920326__F2 Differential cellular components within the bone marrow microenvironment involved in immune evasion of MM ENSG00000170458 ENSG00000163220 PMC8971914__F1 Interactions of circRNAs with methylation: An important aspect of circRNA biogenesis and function ENSG00000149658 ENSG00000198492 ENSG00000275272 ENSG00000180357 ENSG00000165819 PMC6584587__F5 Pathway map for “LRRK2 in neurons in Parkinson’s disease” ENSG00000196961 ENSG00000062485 PMC2788512__F7 Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway ENSG00000107859 ENSG00000162761 ENSG00000163132 ENSG00000164690 ENSG00000125084 PMC9288030__F2 Noncoding RNAs as sensors of tumor microenvironmental stress ENSG00000125538 PMC3047785__F5 CD28 signaling events ENSG00000002330 ENSG00000070831 ENSG00000198793 ENSG00000141968 PMC9632440__F7 Network pharmacology analysis reveals neuroprotective effects of the Qin-Zhi-Zhu-Dan Formula in Alzheimer’s disease ENSG00000002330 ENSG00000177606 ENSG00000171791 ENSG00000073756 PMC7601648__F2 Non-canonical NFKB signalling pathway and the role of ubiquitination ENSG00000104856 ENSG00000186660 ENSG00000264522 ENSG00000131323 ENSG00000127191 PMC2918459__F1 Biosynthetic pathway of ω3 and ω6 polyunsaturated fatty acids (PUFAs) ENSG00000134824 ENSG00000149485 ENSG00000197977 ENSG00000026103 PMC8930976__F2 Queueing theory model of pentose phosphate pathway ENSG00000197713 PMC4885105__F2 Infection cycle of HCV ENSG00000130164 ENSG00000015520 ENSG00000110651 ENSG00000146648 PMC5145800__F1 Astrocytes and neuronal activity play distinct, cooperative roles in neuronal redox homeostasis ENSG00000178573 ENSG00000023909 ENSG00000079999 PMC8074089__F4 Rho Family GTPases and Rho GEFs in Glucose Homeostasis ENSG00000106070 ENSG00000169047 PMC1819569__F6 The signalling pathways involved in Pam3Cys-induced degranulation and cytokine/chemokine production in human LAD 2, MLMC and BMMC ENSG00000174125 ENSG00000108691 PMC2658783__F2 The erbB family and the IGF/IGF-1R system ENSG00000163235 ENSG00000140443 PMC4139483__F1 An Unexpected Journey: Lysine Methylation Across the Proteome ENSG00000103037 ENSG00000173039 ENSG00000143499 PMC7044062__F8 Changes in the urea cycle following LPS stimulation with or without DCA pretreatment ENSG00000148926 ENSG00000036473 PMC8599256__F2 Endogenous estrogens—breast cancer and chemoprevention ENSG00000140505 ENSG00000140465 PMC11989623__F2 Main mechanisms of resistance to ET and/or CDK4/6is in advanced ER+/HER2− breast cancer ENSG00000198793 ENSG00000087586 ENSG00000150457 ENSG00000131023 ENSG00000139618 ENSG00000183765 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000139687 ENSG00000146648 ENSG00000196712 PMC11989623__F1 Complexity of the molecular pathways governing the function of the cyclin-dependent kinases (CDKs) through the cell-division cycle ENSG00000135446 ENSG00000136997 ENSG00000123374 ENSG00000105810 PMC9405369__F1 Clinical Research Progress of Small Molecule Compounds Targeting Nrf2 for Treating Inflammation-Related Diseases ENSG00000181019 ENSG00000178573 ENSG00000023909 ENSG00000079999 PMC9456568__F2 NAD/NAMPT and mTOR Pathways in Melanoma: Drivers of Drug Resistance and Prospective Therapeutic Targets ENSG00000178860 ENSG00000105835 ENSG00000157764 ENSG00000136869 PMC2715958__F2 One possible pathway which regulates cell migration in response to strain on fibronectin ENSG00000291971 PMC2715958__F1 One possible pathway which regulates cell proliferation in response to strain on collagen ENSG00000291971 PMC6163134__F2 Proposed signaling pathways in the development of hepatic portal hypertension ENSG00000108924 ENSG00000163914 PMC5733019__F8 GHK on pulmonary fibrosis ENSG00000197299 ENSG00000100985 PMC5542379__F2 miR-206/133b Cluster: A Weapon against Lung Cancer? ENSG00000071575 ENSG00000164483 ENSG00000171791 PMC5542379__F1 miR-133b/206 Associates with Various Genes Mediating NSCLC Cell Migration and InvasionmiR-206 promoted lung cancer cell apoptosis by targeting c-Met and Bcl2, as well as governed EGFR, MET, and its downstream phosphorylation of ERK1/2 and AKT ENSG00000125398 ENSG00000164483 ENSG00000171791 ENSG00000258643 ENSG00000146648 PMC5404780__F2 Mechanism of action of various Hedgehog pathway inhibitors ENSG00000128602 PMC9682161__F2 Prostaglandin E2 in neuroblastoma: Targeting synthesis or signaling? ENSG00000281324 ENSG00000162337 ENSG00000291971 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC5837124__F3 Various strategies to target Myc ENSG00000136807 ENSG00000141867 ENSG00000136997 ENSG00000087586 ENSG00000277273 ENSG00000166851 PMC8687853__F5 H2A.X Phosphorylation in Oxidative Stress and Risk Assessment in Plasma Medicine ENSG00000164053 ENSG00000002330 ENSG00000171791 ENSG00000168938 ENSG00000138385 ENSG00000084774 PMC11200984__F6 Action of Isoflavone Derived from Soy-Based Tempeh as an Antioxidant and Breast Cancer Inhibitor via Potential Upregulation of miR-7-5p: A Multimodal Analysis Integrating Pharmacoinformatics and Cellular Studies ENSG00000143799 ENSG00000198793 ENSG00000103222 ENSG00000047936 ENSG00000168610 ENSG00000146648 ENSG00000140443 PMC5295490__F4 B3AR signaling activation in cardiomyocytes ENSG00000198626 PMC6685439__F1 Cholesterol biosynthetic/protein prenylation pathway ENSG00000070831 ENSG00000163914 ENSG00000197429 PMC137069__F1 Hh-signaling pathway ENSG00000180447 ENSG00000112210 ENSG00000128602 PMC6627634__F1 Diagram showing the different molecular mechanisms of canonical nucleotide-binding oligomerization domain leucine rich repeat and pyrin domain-containing protein 3 (NLRP3) inflammasome activation ENSG00000162711 ENSG00000172936 ENSG00000168040 ENSG00000168404 PMC7778498__F1 Endosteal, reticular, and vascular niches in the context of bone marrow ENSG00000152266 ENSG00000107562 ENSG00000111537 ENSG00000125538 ENSG00000155011 ENSG00000169884 ENSG00000198125 PMC4052696__F9 Pathway Bridge Based Multiobjective Optimization Approach for Lurking Pathway Prediction ENSG00000145247 PMC11660123__F3 AIM2 in regulating the development of breast cancer and LUAD independent of inflammasome ENSG00000002330 ENSG00000163568 ENSG00000168610 PMC6627634__F2 Diagram showing the different molecular mechanisms of non-canonical NLRP3 inflammasome activations ENSG00000162711 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000168040 PMC11660123__F2 AIM2 regulation in CRC, HCC, and RCC in inflammasome-independent manner ENSG00000163568 ENSG00000198793 ENSG00000277263 PMC4052696__F7 Based on experimental data GDS3634, miR-205 expression effect on prostate cancer cell line, from NCBI public database browser, P value of 8 samples of Student's t-test, microarray data was applied as the link cost for predicted paths ENSG00000064309 ENSG00000163235 ENSG00000087460 PMC9003967__F11 Uncarboxylated osteocalcin promotes proliferation and metastasis of MDA-MB-231 cells through TGFB/SMAD3 signaling pathway ENSG00000087245 ENSG00000170558 ENSG00000132646 PMC6280921__F1 Cross-talk among different signaling pathways involved in MDSCs expansion, activation and function ENSG00000172936 PMC8356724__F1 The BMP-2 signaling pathway ENSG00000170365 PMC9374760__F1 Absolute protein quantitation of the mouse macrophage Toll-like receptor and chemotaxis pathways ENSG00000104856 ENSG00000213928 ENSG00000183735 ENSG00000056558 ENSG00000136869 ENSG00000157625 ENSG00000090376 ENSG00000064012 ENSG00000137275 ENSG00000173039 ENSG00000130159 ENSG00000174516 ENSG00000168040 ENSG00000154124 ENSG00000168610 ENSG00000276561 ENSG00000102034 ENSG00000115415 ENSG00000170458 ENSG00000177606 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000184216 PMC8430922__F3 Nerve Growth Factor: A Potential Therapeutic Target for Lung Diseases PMC4172957__F6 Expression of genes in the canonical complement system pathway ENSG00000039537 ENSG00000244731 ENSG00000062485 ENSG00000236625 PMC4172957__F5 Expression of genes in the Th1 response network and interferon signaling pathway ENSG00000153208 ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000189403 ENSG00000196639 ENSG00000230034 ENSG00000237834 PMC5130170__F1 Modeling Cellular Noise Underlying Heterogeneous Cell Responses in the Epidermal Growth Factor Signaling Pathway ENSG00000138798 ENSG00000146648 PMC9555085__F2 Current understanding of epigenetics role in melanoma treatment and resistance ENSG00000151376 ENSG00000291971 ENSG00000197380 ENSG00000143379 ENSG00000150907 ENSG00000136848 ENSG00000168036 ENSG00000115461 ENSG00000140443 PMC8566418__F2 Estetrol and Mammary Gland: Friends or Foes? ENSG00000082175 ENSG00000291971 ENSG00000160182 ENSG00000152137 ENSG00000196208 PMC4960006__F7 Diagram represents the proposed model of APC regulation of miR-17-92 cluster ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC8898846__F4 Comprehensive Analysis of Immune Infiltrates of Ferroptosis-Related Long Noncoding RNA and Prediction of Colon Cancer Patient Prognoses ENSG00000142192 ENSG00000134982 ENSG00000148798 ENSG00000136997 ENSG00000122008 PMC9128303__F1 IGF-I structure and activity ENSG00000198793 PMC2953417__F1 REGULATION OF NITRIC OXIDE PRODUCTION IN HEALTH AND DISEASE ENSG00000036473 PMC7327052__F3 Centrosome aberrations trigger an immunosuppressive microenvironment ENSG00000183735 ENSG00000167772 ENSG00000164430 ENSG00000134982 PMC7327052__F2 Centrosome aberration-associated molecular pathways in cellular senescence ENSG00000101639 ENSG00000078674 PMC4693897__F8 Proposed mechanism for zinc‐mediated inhibition of interleukin‐1B (IL‐1B) signalling and its role for repression of human T helper type 17 (Th17) responses ENSG00000125538 ENSG00000172936 ENSG00000175104 ENSG00000115594 PMC7790916__F1 Insulin resistance and exaggerated insulin sensitivity triggered by single-gene mutations in the insulin signaling pathway ENSG00000136111 ENSG00000179295 PMC6608000__F8 EtOH metabolism pathway regulates KLF4 expression and function ENSG00000260314 ENSG00000125538 ENSG00000130649 ENSG00000118520 ENSG00000136826 PMC3662904__F1 Transforming growth factor (TGF)B signaling cascade ENSG00000157933 ENSG00000198742 PMC5536940__F1 Transduction of platinum-induced DNA damage: DNA repair or apoptosis ENSG00000149311 ENSG00000012048 ENSG00000083093 ENSG00000139618 PMC8569351__F2 FOXO1: a pivotal pioneer factor in oral squamous cell carcinoma ENSG00000126775 ENSG00000150907 ENSG00000118515 ENSG00000198890 ENSG00000096717 PMC9579336__F3 Synthesis, function, and regulation of sterol and nonsterol isoprenoids ENSG00000113161 ENSG00000120942 PMC9579336__F2 Synthesis, function, and regulation of sterol and nonsterol isoprenoids ENSG00000130164 ENSG00000197429 ENSG00000113161 ENSG00000120942 PMC9579336__F1 Synthesis, function, and regulation of sterol and nonsterol isoprenoids ENSG00000123728 ENSG00000113161 ENSG00000104549 ENSG00000181467 PMC9133562__F3 Auxiliary Role of Heparin in Bone Regeneration and its Application in Bone Substitute Materials ENSG00000198793 ENSG00000134853 ENSG00000122194 PMC9654076__F1 Molecular Targeting of the Most Functionally Complex Gene in Precision Oncology: p53 ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000111837 ENSG00000105810 PMC5580270__F4 Changes in hepatic gene expression associated with the PPARA signalling pathway and fatty acid metabolism between broilers (n = 6) and layers (n = 6) ENSG00000131473 ENSG00000151726 ENSG00000065833 ENSG00000135218 ENSG00000169710 ENSG00000115361 ENSG00000099194 PMC8525106__F4 Key radioresistance regulation models and marker genes identified by integrated transcriptome analysis in nasopharyngeal carcinoma ENSG00000057935 ENSG00000157764 ENSG00000181852 ENSG00000170027 ENSG00000153201 ENSG00000188229 ENSG00000116717 ENSG00000184481 ENSG00000149311 ENSG00000012048 ENSG00000132646 ENSG00000113558 ENSG00000177606 ENSG00000125818 ENSG00000123374 ENSG00000149554 PMC9563254__F5 p21-Activated Kinase: Role in Gastrointestinal Cancer and Beyond ENSG00000136997 ENSG00000168036 ENSG00000168610 PMC8475945__F3 Unfolded Protein Response Pathway in PC3 (A) and ARCaP(M) (B) cells ENSG00000128272 ENSG00000159461 ENSG00000165280 ENSG00000127022 ENSG00000100219 ENSG00000171791 ENSG00000127191 ENSG00000135506 ENSG00000086619 PMC3486458__F7 AMPK/ERK/TSC2/mTOR signaling in PCV2-induced autophagy in PK-15 cells ENSG00000198793 PMC3842585__F2 Mutations in the ERK/MAPK signaling pathway and related second messenger systems ENSG00000231213 ENSG00000172456 ENSG00000116717 ENSG00000173230 ENSG00000164675 PMC5717006__F2 Mevalonate metabolism in immune and cancer cells ENSG00000135218 ENSG00000198793 ENSG00000136997 ENSG00000197429 ENSG00000026103 PMC9374760__F3 Absolute protein quantitation of the mouse macrophage Toll-like receptor and chemotaxis pathways ENSG00000108702 ENSG00000185436 ENSG00000274571 ENSG00000292250 ENSG00000245848 ENSG00000164430 ENSG00000172216 ENSG00000184995 ENSG00000228083 ENSG00000233816 ENSG00000164400 ENSG00000092067 ENSG00000186803 ENSG00000168404 ENSG00000162892 ENSG00000147573 ENSG00000123091 ENSG00000176624 ENSG00000137275 ENSG00000136694 ENSG00000108342 ENSG00000154124 ENSG00000276561 ENSG00000127445 ENSG00000226275 ENSG00000105397 ENSG00000170458 ENSG00000187554 ENSG00000172005 ENSG00000102970 ENSG00000161929 ENSG00000185792 ENSG00000121060 ENSG00000285379 ENSG00000115009 ENSG00000174123 ENSG00000188379 ENSG00000105329 ENSG00000119401 ENSG00000163568 ENSG00000174885 ENSG00000168811 ENSG00000142224 ENSG00000150782 ENSG00000088888 ENSG00000049130 ENSG00000078747 ENSG00000056558 ENSG00000147896 ENSG00000185591 ENSG00000128342 ENSG00000164342 ENSG00000236637 ENSG00000174125 ENSG00000124256 ENSG00000275718 ENSG00000275385 ENSG00000173039 ENSG00000130159 ENSG00000174516 ENSG00000168040 ENSG00000127191 ENSG00000234829 ENSG00000168610 ENSG00000277943 ENSG00000276068 ENSG00000090432 ENSG00000108691 ENSG00000128272 ENSG00000111537 ENSG00000102034 ENSG00000177606 ENSG00000164136 ENSG00000291876 ENSG00000083799 ENSG00000123268 PMC9374760__F2 Absolute protein quantitation of the mouse macrophage Toll-like receptor and chemotaxis pathways ENSG00000138639 ENSG00000107562 ENSG00000090104 ENSG00000070831 ENSG00000291971 ENSG00000100852 ENSG00000116741 ENSG00000124126 ENSG00000121879 ENSG00000128617 ENSG00000267534 ENSG00000121966 ENSG00000159788 ENSG00000120063 ENSG00000281614 ENSG00000076928 ENSG00000170989 PMC9374760__F4 Absolute protein quantitation of the mouse macrophage Toll-like receptor and chemotaxis pathways ENSG00000140992 ENSG00000138639 ENSG00000175866 ENSG00000102606 ENSG00000153823 ENSG00000134982 ENSG00000138443 ENSG00000158195 ENSG00000100852 ENSG00000124126 ENSG00000254999 ENSG00000171791 ENSG00000061676 ENSG00000128617 ENSG00000149781 ENSG00000136002 ENSG00000159788 ENSG00000112290 ENSG00000148498 ENSG00000107263 ENSG00000076928 ENSG00000126247 ENSG00000173599 ENSG00000090104 ENSG00000065559 ENSG00000116741 ENSG00000267534 ENSG00000120063 ENSG00000116584 ENSG00000170989 ENSG00000107562 ENSG00000002330 ENSG00000070831 ENSG00000291971 ENSG00000095015 ENSG00000168036 ENSG00000158517 ENSG00000169032 ENSG00000121879 ENSG00000092820 ENSG00000121966 ENSG00000089159 ENSG00000113263 ENSG00000157764 ENSG00000109320 ENSG00000173039 ENSG00000281614 ENSG00000177189 ENSG00000120899 ENSG00000067606 ENSG00000010810 ENSG00000177606 ENSG00000015285 ENSG00000115020 PMC8576142__F3 Myeloid dysregulation and therapeutic intervention in COVID-19 ENSG00000108691 ENSG00000172936 PMC8389562__F5 Non-Coding RNAs in the Regulation of the Proto-Oncogene MYC in Different Types of Cancer ENSG00000141867 ENSG00000178585 ENSG00000110395 ENSG00000197961 ENSG00000171634 ENSG00000136997 ENSG00000048028 PMC8389562__F4 Non-Coding RNAs in the Regulation of the Proto-Oncogene MYC in Different Types of Cancer ENSG00000107164 ENSG00000136997 ENSG00000121067 ENSG00000073792 ENSG00000187772 PMC8389562__F3 Non-Coding RNAs in the Regulation of the Proto-Oncogene MYC in Different Types of Cancer ENSG00000131914 ENSG00000158290 ENSG00000147162 ENSG00000197961 ENSG00000136997 ENSG00000274089 ENSG00000048028 ENSG00000187772 ENSG00000163507 PMC8476494__F8 Hypothalamic-pituitary adrenal-axis, toll-like receptors, and macrophage polarization in pre-atherosclerotic changes induced by social isolation stress in mice ENSG00000136869 ENSG00000162692 PMC7378251__F3 Expression of genes related to starch and sucrose metabolism, glycolysis, TCA cycle and amino acids pathway under CK, MD, AT and SD ENSG00000131473 ENSG00000070669 ENSG00000091140 PMC4381956__F1 Complement in Monoclonal Antibody Therapy of Cancer ENSG00000039537 ENSG00000113600 ENSG00000244414 ENSG00000203710 ENSG00000154059 ENSG00000244731 ENSG00000166278 ENSG00000236625 PMC1780025__F2 Heterogeneity of Pacemaking Ability among SCN Neurons Robust rhythm generation in SCN neurons PMC5527950__F2 Internalization routes influence signaling output ENSG00000154342 ENSG00000281324 ENSG00000168036 ENSG00000146648 PMC9133562__F2 Auxiliary Role of Heparin in Bone Regeneration and its Application in Bone Substitute Materials ENSG00000121989 ENSG00000204217 ENSG00000114739 PMC3150418__F9 NFKB signaling participates in both Receptor Activator of NFKB Ligand- (RANKL) and interleukin-4- (IL-4) induced macrophage fusion: Receptor cross-talk leads to alterations in NFKB pathways ENSG00000104856 ENSG00000164935 ENSG00000173039 ENSG00000026508 PMC5680911__F7 Simplified graphical scheme representing the effect of Caspase-8 depletion on hepatic apoptosis and steatosis in the pathogenesis of ALD ENSG00000132906 ENSG00000042832 ENSG00000130649 ENSG00000064012 ENSG00000164305 PMC4081080__F3 miR-143/145 modulate signaling through the Ras-MAPK pathway ENSG00000146648 ENSG00000124782 PMC5614474__F2 Multiple and bidirectional connections between actin dynamics and endocytosis ENSG00000019991 ENSG00000156299 ENSG00000132698 ENSG00000165527 PMC7357716__F3 Metabolic Messengers: Adiponectin ENSG00000171105 ENSG00000096717 PMC5460571__F4 Representation of the molecular interaction pathway analysis of the associated and causal genes linked to aneuploidy ENSG00000142192 ENSG00000124275 ENSG00000291561 ENSG00000122512 PMC11507252__F7 Protective and Detoxifying Effects of Resveratrol on Zearalenone-Mediated Toxicity: A Review ENSG00000198793 ENSG00000057663 PMC4533766__F7 Expression profile of P ENSG00000170430 ENSG00000134575 ENSG00000166278 ENSG00000142513 PMC7931557__F8 Proposed model of the mechanism underlying the expression and function of LINC00958 in TSCC cell proliferation ENSG00000123219 ENSG00000123908 PMC11507252__F6 Protective and Detoxifying Effects of Resveratrol on Zearalenone-Mediated Toxicity: A Review ENSG00000096717 ENSG00000106459 PMC5614474__F3 Transcriptional programs controlling endocytosis and genetic reprogramming by endocytosis ENSG00000112561 ENSG00000164695 ENSG00000146648 ENSG00000136048 PMC11507252__F5 Protective and Detoxifying Effects of Resveratrol on Zearalenone-Mediated Toxicity: A Review ENSG00000162711 ENSG00000172936 ENSG00000136869 PMC8405670__F4 Comparative analysis of therapeutic effects between medium cut-off and high flux dialyzers using metabolomics and proteomics: exploratory, prospective study in hemodialysis ENSG00000113889 ENSG00000138207 ENSG00000117601 ENSG00000148702 ENSG00000120885 ENSG00000184500 PMC3845601__F2 Wnt/Beta-catenin signaling pathway ENSG00000156076 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000168036 PMC6279509__F9 Untangling the response of bone tumor cells and bone forming cells to matrix stiffness and adhesion ligand density by means of hydrogels ENSG00000087245 ENSG00000168036 ENSG00000100985 PMC9465090__F1 System Xc −/GSH/GPX4 axis: An important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy ENSG00000168003 ENSG00000148346 ENSG00000128272 ENSG00000151012 ENSG00000167468 ENSG00000197429 ENSG00000171848 ENSG00000185591 ENSG00000162772 ENSG00000146648 PMC4654121__F6 Suppression of the GTPase-activating protein RGS10 increases Rheb-GTP and mTOR signaling in ovarian cancer cells ENSG00000148908 ENSG00000198793 PMC10940142__F1 Schematic overview describing the target pathway and overall metabolic strategies for heme production ENSG00000108582 ENSG00000105251 PMC11727420__F2 Signaling interactions between the Wnt/Frizzled pathway, MINK1, Prickle1, and their downstream effects on cellular processes ENSG00000163539 ENSG00000144824 ENSG00000141503 PMC5764090__F2 HiJAKing the Epigenome in Leukemia and Lymphoma ENSG00000077150 ENSG00000144802 ENSG00000140379 ENSG00000100906 ENSG00000156127 ENSG00000177606 ENSG00000136997 ENSG00000137265 ENSG00000118515 ENSG00000172936 ENSG00000168610 PMC5838326__F4 Changes in the hepatic expression levels of genes for gluconeogenesis pathway following castration of bulls ENSG00000262785 ENSG00000111058 ENSG00000175198 ENSG00000124370 ENSG00000114054 ENSG00000173599 ENSG00000124253 ENSG00000131828 ENSG00000091140 ENSG00000159399 PMC6316656__F2 Hedgehog pathway activation in cancer ENSG00000128602 PMC11727420__F5 MINK1 and Hippo pathway regulation ENSG00000141503 ENSG00000150457 ENSG00000131023 PMC5764090__F1 HiJAKing the Epigenome in Leukemia and Lymphoma ENSG00000164399 ENSG00000128342 ENSG00000168610 PMC11727420__F4 MINK1 and JNK signaling pathway interaction ENSG00000141503 ENSG00000154310 PMC11011055__F7 Targeting Siglec–Sialylated MUC1 Immune Axis in Cancer ENSG00000159921 ENSG00000069482 ENSG00000095380 PMC11854358__F8 Analysis of cell cycle pathways and differentially expressed genes because of different levels of PFESA-BP2 exposure ENSG00000120833 ENSG00000198901 ENSG00000114346 ENSG00000013810 ENSG00000164109 ENSG00000135446 ENSG00000131747 ENSG00000136997 ENSG00000123374 ENSG00000073111 ENSG00000145386 ENSG00000104081 PMC11854358__F7 Proposed effect of low-dose PFESA-BP2 exposure on the hepatic fibrosis signaling pathway in the liver [59] ENSG00000089685 ENSG00000136997 ENSG00000145386 ENSG00000146648 PMC8730820__F2 Multiple MuSK signaling pathways and the aging neuromuscular junction ENSG00000180210 ENSG00000170365 ENSG00000134569 ENSG00000030304 ENSG00000168036 ENSG00000084774 PMC6115007__F2 Iron in Type 1 Diabetes Etiology: A Systematic Review of New Evidence on a Long-Standing Mystery ENSG00000010704 PMC5576560__F2 Ten Strategies of Interferon Evasion by Viruses ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000135828 ENSG00000142166 PMC6868788__F8 Long noncoding RNA 00976 promotes pancreatic cancer progression through OTUD7B by sponging miR-137 involving EGFR/MAPK pathway ENSG00000087245 ENSG00000264522 ENSG00000123374 ENSG00000100985 PMC8779696__F1 Host Non-Coding RNA Regulates Influenza A Virus Replication ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000160710 ENSG00000276561 ENSG00000140464 PMC11292300__F4 The rationale for possible targeted therapies in CMTC ENSG00000157764 ENSG00000134982 ENSG00000198793 ENSG00000136997 ENSG00000102312 ENSG00000168610 PMC11292300__F2 WNT signaling pathway in CMTC ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC5337177__F2 Mechanisms by which mild mitochondrial uncoupling protects neurons against oxidative stress, excitotoxicity and the accumulation of disease-related self-aggregating proteins such as amyloid Beta-peptide, Tau and Alpha-synuclein ENSG00000156026 ENSG00000198793 ENSG00000198576 ENSG00000142082 PMC7933988__F7 Action of mesenchymal stem cells in the vestibular microenvironment ENSG00000178860 ENSG00000123609 ENSG00000136997 ENSG00000168610 PMC7289712__F6 KEGG relationship network diagram ENSG00000108691 ENSG00000125538 ENSG00000113520 PMC7189706__F5 Hyperglycaemia may influence ten-eleven translocation (TET)-dependent O-GlcNAcylation of the histone methyltransferase SET1/COMPASS complex ENSG00000147162 ENSG00000187605 PMC5714221__F9 H1 involvement in the repression of the interferon response ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000125347 ENSG00000276561 PMC4471797__F1 Wnt/Beta-catenin signaling pathway ENSG00000134982 PMC6217807__F6 Hydrogel Environment Supports Cell Culture Expansion of a Grade IV Astrocytoma ENSG00000169291 ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000138430 ENSG00000146648 PMC5282855__F1 Biosynthetic pathways of tetrapyrrole compounds ENSG00000106078 ENSG00000062485 PMC6217807__F5 Hydrogel Environment Supports Cell Culture Expansion of a Grade IV Astrocytoma ENSG00000002330 PMC7688918__F3 In response to I/R injury, neutrophils migrate from the circulation to the injured heart in response to CXCL and release S100A8/A9 ENSG00000143546 ENSG00000163739 ENSG00000136869 ENSG00000106459 PMC8746635__F7 Anti-Inflammatory Activities of the Ethanol Extract of Prasiola japonica, an Edible Freshwater Green Algae, and Its Various Solvent Fractions in LPS-Induced Macrophages and Carrageenan-Induced Paw Edema via the AP-1 Pathway ENSG00000087245 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000100985 PMC8881374__F2 10 Years of GWAS discovery in endometrial cancer: Aetiology, function and translation ENSG00000135547 ENSG00000105193 ENSG00000123454 ENSG00000136942 ENSG00000281244 ENSG00000280858 ENSG00000281165 ENSG00000131242 ENSG00000105640 ENSG00000136997 ENSG00000166073 ENSG00000105810 ENSG00000162552 ENSG00000108298 ENSG00000182742 ENSG00000280584 ENSG00000284869 ENSG00000173917 ENSG00000196990 ENSG00000042429 ENSG00000106299 ENSG00000137876 ENSG00000280479 ENSG00000281022 ENSG00000281245 ENSG00000276920 ENSG00000230778 ENSG00000281879 ENSG00000180592 ENSG00000281024 ENSG00000197859 ENSG00000164363 ENSG00000002919 ENSG00000161016 ENSG00000128944 ENSG00000102981 ENSG00000128829 ENSG00000108511 ENSG00000140319 ENSG00000070831 ENSG00000140320 ENSG00000087586 ENSG00000135111 ENSG00000104081 ENSG00000123096 ENSG00000137841 ENSG00000174358 ENSG00000260027 ENSG00000135446 ENSG00000164362 ENSG00000153395 ENSG00000112306 PMC2877394__F1 ER and SR interactions within mammalian cells ENSG00000177169 ENSG00000198382 ENSG00000167323 ENSG00000198793 ENSG00000100219 ENSG00000171791 PMC3239234__F3 Various signaling pathways modulated by the primary cilium ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC4161976__F7 MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer ENSG00000077463 PMC9259972__F2 Long Non-coding RNA HOTAIR in Central Nervous System Disorders: New Insights in Pathogenesis, Diagnosis, and Therapeutic Potential ENSG00000152348 ENSG00000162711 ENSG00000127328 ENSG00000125538 ENSG00000172936 PMC5779720__F2 Distribution of fluxes in the central metabolism predicted by pFBA for the models: iFF708 (green), iMM904 (blue), iTO977 (orange) and Yeast 6 (black) ENSG00000122966 ENSG00000172005 PMC2720726__F1 IFNB activated pathway ENSG00000213928 ENSG00000115415 ENSG00000125347 ENSG00000142166 PMC9376318__F3 CXCL5: A coachman to drive cancer progression ENSG00000186810 ENSG00000125398 ENSG00000168610 PMC5779720__F4 Flux distributions simulated with lMOMA for the mevalonate mutant (A) and the acetate mutant (B) using the improved flux distribution as the reference ENSG00000122966 ENSG00000173599 ENSG00000172005 ENSG00000094975 PMC6803553__F3 Signal transduction of GDF11 ENSG00000095739 ENSG00000135414 ENSG00000175104 PMC6202106__F7 The TGFB/BAMBI pathway ENSG00000095739 ENSG00000049768 PMC2238720__F2 Monarch-1/PYPAF7 and other CATERPILLER (CLR, NOD, NLR) proteins with negative regulatory functions ENSG00000104856 ENSG00000173039 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC5190068__F3 KCNN4 and S100A14 act as predictors of recurrence in optimally debulked patients with serous ovarian cancer ENSG00000189334 ENSG00000104783 ENSG00000136826 PMC7550684__F1 Signaling pathway of Interleukin-17A (IL-17A) ENSG00000196843 ENSG00000082512 ENSG00000175104 ENSG00000127191 PMC10178416__F2 Schematic drawing presenting signaling pathways affected by ferulic acid ENSG00000105329 ENSG00000136869 ENSG00000079999 PMC9495760__F1 Tyrosine Phosphatase SHP2: A New Target for Insulin Resistance? ENSG00000171105 ENSG00000125538 ENSG00000169047 PMC4331476__F4 Representative illustration of key gene distribution (hsa04720 and LAP_hsa04720s) ENSG00000118898 PMC3232027__F2 Identification and development of mPGES-1 inhibitors: where we are at? PMC4030640__F2 Molecular and biophysical characterization of the human blood-nerve barrier: Current concepts ENSG00000168036 PMC3994981__F2 PI3K and Cancer: Lessons, Challenges and Opportunities ENSG00000177169 ENSG00000106070 ENSG00000198793 ENSG00000136997 ENSG00000164327 PMC3994981__F1 PI3K and Cancer: Lessons, Challenges and Opportunities ENSG00000198793 ENSG00000121879 PMC6101676__F1 Mevalonate-isoprenoid-cholesterol pathway and pharmacological agents that inhibit the synthesis of key intermediates ENSG00000163914 ENSG00000197429 ENSG00000113161 PMC10272955__F8 Graphical summary of the signaling pathway that mediates fenofibrate (FF)-induced cytoprotection against cisplatin toxicity ENSG00000106546 ENSG00000079999 PMC4839493__F1 The metabolic pathway for vitamin D ENSG00000111012 ENSG00000118972 ENSG00000152266 ENSG00000019186 ENSG00000186104 PMC4839493__F7 1,25(OH)2D3-induced signaling pathways involved in the regulation of cell proliferation, apoptosis, and inflammation in cancer ENSG00000134982 ENSG00000123374 ENSG00000146648 PMC8106830__F1 Cascade of innate immune response against intestinal fungi ENSG00000163464 ENSG00000187796 PMC2653622__F2 PRIMARY CILIUM: AT THE CROSSROADS OF MAMMALIAN HEDGEHOG SIGNALING ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC8146326__F8 Extracellular Vesicle Release Promotes Viral Replication during Persistent HCV Infection ENSG00000067900 ENSG00000165527 PMC4452063__F2 The Wnt/Beta-catenin signaling pathway and the regeneration therapy drug candidates discussed in the paper ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000168036 PMC4452063__F1 The Wnt/Beta-catenin signaling pathway and the oncology-indication drug candidates discussed in the paper ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC7645992__F10 Prosed schematic proposed mechanism underlying the impact of DDP4 inhibition on protecting the cell from apoptosis and oxidative stress through regulating the PI3K/AKT/m-TOR signaling pathway ENSG00000125538 ENSG00000198793 PMC4434706__F1 Two S-phase checkpoint responses in S ENSG00000276618 ENSG00000260314 ENSG00000138346 PMC7550684__F3 Relationship between IL-17A and astrocytes ENSG00000125538 ENSG00000168610 PMC11993841__F6 Influence of porous metal materials on osteogenesis ENSG00000168036 PMC11899827__F1 IL-17 signaling pathway in the pathophysiology of spondyloarthritis ENSG00000162594 ENSG00000163702 PMC9187083__F9 Understanding pathogen–host interplay by expression profiles of lncRNA and mRNA in the liver of Echinococcus multilocularis-infected mice ENSG00000169245 ENSG00000115415 ENSG00000122877 ENSG00000172936 ENSG00000150455 ENSG00000049768 ENSG00000168610 PMC2692823__F2 Hypoxic pulmonary vasoconstriction and their roles in pulmonary hypertension: new findings for an old problem ENSG00000167323 ENSG00000137672 ENSG00000174611 PMC9585190__F7 Metformin on Sonic hedgehog subgroup medulloblastoma progression: In vitro and in vivo studies ENSG00000164690 ENSG00000128602 PMC8062309__F2 T helper cell changes locally and peripherally in healthy pregnancy and preeclampsia ENSG00000111537 PMC8062309__F1 Local and systemic complement activation in preeclampsia and healthy pregnancy and complement-modulating medications ENSG00000244414 ENSG00000288512 ENSG00000196352 ENSG00000117335 ENSG00000000971 ENSG00000166278 ENSG00000182326 PMC4487780__F1 NAD+ metabolism and the control of energy homeostasis - a balancing act between mitochondria and the nucleus ENSG00000105835 ENSG00000278488 ENSG00000157064 ENSG00000173614 PMC3316974__F1 AKT-mTOR signaling pathway showing rapamycin inhibition sites in astrocytomas ENSG00000198793 PMC3159974__F4 Predicted synthetic lethal gene pairs in TCA cycle (A), phosphatidylserine biosynthesis (B) and pentose-phosphate pathway (C) ENSG00000197713 ENSG00000185813 ENSG00000174915 ENSG00000173599 ENSG00000153574 ENSG00000111666 ENSG00000134255 ENSG00000156471 PMC209477__F2 gp130 cytokine family pathways on anterior pituitary cells ENSG00000099985 ENSG00000242689 ENSG00000170458 ENSG00000128342 PMC8328385__F1 Alopecia Areata: An Autoimmune Disease of Multiple Players ENSG00000169248 ENSG00000169245 ENSG00000186810 ENSG00000138755 ENSG00000105656 PMC5592089__F1 PI3K/AKT/mTOR pathway and interaction with PTEN and TSC1/TSC2 ENSG00000125482 ENSG00000002330 ENSG00000169047 ENSG00000198793 ENSG00000146648 PMC5520933__F1 The lithium targeted cellular and molecular mechanism by activating several neurotrophic and associated signaling in Alzheimer’s disease ENSG00000084093 ENSG00000142192 ENSG00000105723 PMC6513185__F4 Effects of flavonoids on signaling pathway of NLRP3 inflammasome activation ENSG00000162711 ENSG00000125538 ENSG00000136869 ENSG00000265972 PMC6412533__F10 Gemcitabine pathway extracted from PharmGkb database ENSG00000162368 ENSG00000167325 ENSG00000171848 ENSG00000158825 ENSG00000112759 ENSG00000129187 ENSG00000197506 PMC4468843__F1 NFKB pathway ENSG00000125538 ENSG00000172936 PMC7235190__F5 Regulatory mechanism of HDAC2/3 on LPL expression in SH-SY5Y cells ENSG00000171720 ENSG00000196591 PMC4061164__F1 Cisplatin-induced inflammation is mediated through multiple effectors including activation of NFkB, TNFA, and PARP ENSG00000019991 ENSG00000162692 ENSG00000168610 PMC6513185__F2 Flavonoids on the expression of MMP and ADAMTS in osteoarthritis ENSG00000115415 PMC6099536__F1 IL-33 signaling pathway ENSG00000137033 ENSG00000132478 ENSG00000172936 ENSG00000185187 ENSG00000184216 PMC3094853__F1 CHS-catalyzed synthesis of unnatural polyphenols from cinnamoyl-SNAc starter substrates with a) malonyl-CoA and b) methylmalonyl-CoA as extender units ENSG00000180245 PMC9253771__F3 Combinatorial CRISPR Interference Library for Enhancing 2,3-BDO Production and Elucidating Key Genes in Cyanobacteria ENSG00000166278 PMC3780472__F2 Biochemical changes during EMT in fibrosis ENSG00000169554 ENSG00000170558 PMC5929146__F1 Metabolomics Applied to Islet Nutrient Sensing Mechanisms ENSG00000173599 ENSG00000079432 PMC3270883__F1 Exiting from uncharted territory: hepatitis C virus assembles in mouse cell lines ENSG00000130164 ENSG00000073060 ENSG00000110651 PMC6539061__F2 Polycystin-associated pathogenic mechanisms in human diseases ENSG00000115415 ENSG00000168610 PMC7177523__F2 Schematic figures showing various signaling molecules influenced by the CO-HO-1 pathway ENSG00000198793 ENSG00000145979 ENSG00000139211 ENSG00000096717 PMC7345337__F5 Gene–gene interaction network analysis ENSG00000172680 ENSG00000171105 ENSG00000005339 ENSG00000157764 ENSG00000102226 ENSG00000050748 ENSG00000106070 ENSG00000118515 ENSG00000145782 PMC6406504__F2 Differentiated insulin-producing cells (IPCs) for transplantation ENSG00000019991 ENSG00000139515 ENSG00000182759 ENSG00000164690 ENSG00000106331 PMC11534612__F1 Pathophysiologic roles of IL-17 signaling in cardiac fibrosis ENSG00000165556 ENSG00000169245 ENSG00000163739 ENSG00000082512 ENSG00000169429 ENSG00000056736 ENSG00000175104 ENSG00000127191 ENSG00000163702 PMC7957753__F9 Signal transduction and regulation of secondary metabolism in response to salt stress in S ENSG00000136997 PMC4032892__F1 Schema of PI3K/mTOR and other oncogenic signaling pathways in hematologic malignancies ENSG00000198793 PMC4516161__F4 CIB1 regulation of TNBC cell survival and potential role of CIB1 in non-oncogene addiction ENSG00000149269 PMC4316650__F3 Pathways and networks associated with proteins with differential abundance according to IPA ENSG00000129455 ENSG00000180210 ENSG00000009724 ENSG00000142798 ENSG00000134982 ENSG00000171560 ENSG00000132693 ENSG00000062485 ENSG00000106927 PMC4956769__F4 Features of an altered AMPK metabolic pathway in Gilbert’s Syndrome, and its role in metabolic health ENSG00000096088 ENSG00000096717 PMC4283800__F1 Hypoxia and the extracellular matrix: drivers of tumour metastasis ENSG00000115318 ENSG00000129038 ENSG00000138131 ENSG00000149380 ENSG00000134013 ENSG00000106397 ENSG00000083444 ENSG00000152952 PMC4766460__F2 Plasticity of gene‐regulatory networks controlling sex determination: of masters, slaves, usual suspects, newcomers, and usurpators ENSG00000169218 ENSG00000125398 ENSG00000168066 ENSG00000137090 ENSG00000005513 ENSG00000135409 ENSG00000168229 ENSG00000168036 ENSG00000134595 ENSG00000102678 PMC6554024__F5 Decoding type I and III interferon signalling during viral infection ENSG00000213928 ENSG00000105397 ENSG00000115415 PMC6554024__F4 Decoding type I and III interferon signalling during viral infection ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000172936 ENSG00000107201 ENSG00000276561 ENSG00000164342 PMC5417569__F6 Transcriptome analysis of muskrat scented glands degeneration mechanism ENSG00000049323 ENSG00000170365 ENSG00000137834 ENSG00000111537 ENSG00000100387 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000185591 ENSG00000164093 PMC4404594__F1 Model of CIP2A involvement in the EGFR-RAS signaling pathways ENSG00000146648 ENSG00000163507 PMC5417569__F5 Transcriptome analysis of muskrat scented glands degeneration mechanism ENSG00000182533 ENSG00000041982 ENSG00000156026 ENSG00000186716 PMC10539698__F3 Emerging roles of metabolism in the crosstalk between breast cancer cells and tumor-associated macrophages ENSG00000198793 ENSG00000121807 ENSG00000168610 PMC5938036__F2 The metabolites generated from alternative vitamin D metabolic pathway ENSG00000111012 ENSG00000019186 ENSG00000069667 ENSG00000135929 PMC5287080__F3 Transforming growth factor B (TGFB)-induced activation of the PI3K-Akt pathway ENSG00000122691 PMC5287080__F2 Transforming growth factor B (TGFB)-induced activation of c-Jun amino terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) signaling, and the IKB kinase (IKK) pathway ENSG00000137834 ENSG00000175104 PMC5287080__F1 Transforming growth factor B (TGFB)-induced activation of the extracellular signal-regulated kinase (Erk) mitogen-activated protein kinase (MAPK) pathway PMC3397508__F1 Possible molecular mechanisms of Ngb neuroprotection by modulating cell death/survival signaling pathways ENSG00000179091 ENSG00000166278 PMC4306509__F6 Human disease mutations in short linear motifs ENSG00000002330 ENSG00000198793 ENSG00000123374 ENSG00000171791 ENSG00000167034 PMC7809767__F3 AURKA interactome and related signaling pathways ENSG00000129474 ENSG00000104365 ENSG00000115163 ENSG00000100906 ENSG00000153094 ENSG00000151849 ENSG00000168036 ENSG00000087586 ENSG00000150457 ENSG00000010244 ENSG00000182541 ENSG00000104064 ENSG00000186575 ENSG00000013810 ENSG00000006451 PMC8905338__F5 Personalized Management of Pheochromocytoma and Paraganglioma ENSG00000135956 ENSG00000153208 ENSG00000180616 ENSG00000077782 ENSG00000146648 ENSG00000196712 PMC2907875__F8 Estrogen and Xenoestrogens in Breast Cancer ENSG00000168952 ENSG00000164056 PMC5742588__F3 The folate cycle is fueled by the serine synthesis pathway (SSP) and extracellular serine ENSG00000284320 ENSG00000100714 ENSG00000135069 ENSG00000146733 PMC3387977__F3 Targets for inhibition within the EGFR signaling pathway ENSG00000163235 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8669111__AF1 Glutathione synthesis primes monocytes metabolic and epigenetic pathway for Beta-glucan-trained immunity ENSG00000122966 ENSG00000198793 ENSG00000115419 ENSG00000159399 PMC3804751__F7 Model showing the cRAF-dependent modulation of DC responses by TcES ENSG00000172936 ENSG00000136869 PMC6933576__F11 Apoptotic pathway and targets for complexes 1, 2, 3, and 4 ENSG00000132906 ENSG00000064012 ENSG00000164305 PMC4401614__F1 Cbl pathways ENSG00000110395 ENSG00000134982 PMC4046670__F6 Prioritized genes in apoptosis and TNFR2 signaling pathways ENSG00000002330 ENSG00000026103 PMC4086377__F1 TGFB Signaling in Wound Epithelialization ENSG00000137834 ENSG00000105329 PMC9162042__F3 Multifaceted regulation and functions of 53BP1 in NHEJ-mediated DSB repair (Review) ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000080345 ENSG00000143476 ENSG00000139842 ENSG00000185591 ENSG00000164916 ENSG00000101557 PMC6171999__F1 Targeting B-cell receptor signaling in leukemia and lymphoma: how and why? ENSG00000095585 ENSG00000186716 ENSG00000010671 PMC5356579__F2 Somatic POLE P286R mutation defines a unique subclass of colorectal cancer featuring hypermutation, representing a potential genomic biomarker for immunotherapy ENSG00000121989 ENSG00000157764 ENSG00000162337 ENSG00000065361 ENSG00000134982 ENSG00000168036 ENSG00000117713 ENSG00000149311 ENSG00000125398 ENSG00000155011 ENSG00000136997 ENSG00000050165 ENSG00000104371 ENSG00000168646 ENSG00000140443 ENSG00000109670 PMC5122439__F2 RAS-MAPK pathway epigenetic activation in cancer: miRNAs in action ENSG00000157764 ENSG00000115904 ENSG00000166068 ENSG00000146648 ENSG00000140443 PMC3693464__F1 Transcriptional Control of Cellular Metabolism by mTOR Signaling ENSG00000149311 ENSG00000146648 ENSG00000196712 PMC3806867__F5 High-Throughput 3D Screening Reveals Differences in Drug Sensitivities between Culture Models of JIMT1 Breast Cancer Cells ENSG00000100234 ENSG00000148400 ENSG00000113140 ENSG00000150093 ENSG00000124107 ENSG00000104368 ENSG00000168461 ENSG00000175832 ENSG00000005893 ENSG00000163993 ENSG00000111186 ENSG00000115461 ENSG00000125968 ENSG00000134531 PMC8818677__F9 Everolimus Alleviates Renal Allograft Interstitial Fibrosis by Inhibiting Epithelial-to-Mesenchymal Transition Not Only via Inducing Autophagy but Also via Stabilizing IKBA ENSG00000145604 ENSG00000177169 ENSG00000198793 PMC9708732__F3 Microglia autophagy in ischemic stroke: A double-edged sword ENSG00000177169 ENSG00000162711 ENSG00000136869 ENSG00000127191 ENSG00000145782 ENSG00000057663 PMC12078810__F7 ART inhibits hepatocellular carcinoma cells ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC5954603__F1 Involvement of exosomes in peritoneal dissemination ENSG00000026508 ENSG00000146648 PMC3061884__F9 100 frequent associations obtained after p value cut off in MCL with CDCOCA ENSG00000073584 ENSG00000156482 ENSG00000035681 ENSG00000076604 ENSG00000198286 PMC8977221__F1 Systemic Therapy for Hepatocellular Carcinoma: Current Updates and Outlook PMC9484955__F6 Protective Effect of Natural Medicinal Plants on Cardiomyocyte Injury in Heart Failure: Targeting the Dysregulation of Mitochondrial Homeostasis and Mitophagy ENSG00000133895 ENSG00000069509 ENSG00000214253 PMC7247011__F5 Fe deficiency responses in photosynthetic organisms ENSG00000182511 ENSG00000173599 ENSG00000166278 PMC8745381__F3 Melatonin in Obesity: A Review ENSG00000162711 ENSG00000167772 ENSG00000165030 ENSG00000136869 ENSG00000005381 ENSG00000096717 ENSG00000168610 PMC7247011__F3 Fe-responsive proteins with relevance for photosynthesis in Cyanobacteria, Chlamydomonas, and land plants ENSG00000196531 ENSG00000182511 ENSG00000173599 PMC9484955__F1 Protective Effect of Natural Medicinal Plants on Cardiomyocyte Injury in Heart Failure: Targeting the Dysregulation of Mitochondrial Homeostasis and Mitophagy ENSG00000162711 ENSG00000150782 ENSG00000198626 PMC8955027__F2 Glucose Metabolism and Aging of Hematopoietic Stem and Progenitor Cells ENSG00000095321 ENSG00000117118 ENSG00000163541 ENSG00000127884 ENSG00000117054 ENSG00000074800 ENSG00000178537 ENSG00000092621 ENSG00000100412 ENSG00000100504 ENSG00000146701 ENSG00000091140 ENSG00000164778 ENSG00000062485 ENSG00000125166 ENSG00000178860 ENSG00000131473 ENSG00000262785 ENSG00000067057 ENSG00000138029 ENSG00000100994 ENSG00000018510 ENSG00000105953 ENSG00000172340 ENSG00000131828 ENSG00000115361 ENSG00000110435 ENSG00000122971 ENSG00000152556 PMC7910587__F6 Campylobacter jejuni CiaD effector co-opts the host cell protein IQGAP1 to promote cell entry ENSG00000070831 ENSG00000291971 ENSG00000140575 ENSG00000160293 ENSG00000146648 PMC3061884__F7 100 frequent associations obtained after p value cut off in BLCA with CDCOCA ENSG00000120910 ENSG00000175166 ENSG00000168522 PMC6005571__F10 Neurogenesis and mediators of neuroendocrine stress responses ENSG00000145864 ENSG00000097033 ENSG00000105835 ENSG00000152495 ENSG00000164176 ENSG00000118816 ENSG00000171450 ENSG00000164326 ENSG00000170419 ENSG00000164754 ENSG00000181195 ENSG00000196689 ENSG00000173406 ENSG00000102974 ENSG00000177425 ENSG00000135919 PMC5979342__F5 miR-302s target genes are involved in the loss of epithelial phenotype ENSG00000008710 ENSG00000138795 ENSG00000177485 ENSG00000134982 ENSG00000077279 ENSG00000135414 ENSG00000163083 ENSG00000168615 ENSG00000102678 ENSG00000053747 ENSG00000184845 ENSG00000162761 ENSG00000116132 ENSG00000113361 ENSG00000104290 ENSG00000026508 ENSG00000043039 ENSG00000114166 ENSG00000169851 PMC6072839__F2 Molecular signalling of TRAIL ENSG00000137275 ENSG00000168040 ENSG00000127191 PMC5396384__F3 Inositol polyphosphates synthetic pathway ENSG00000274958 ENSG00000137825 ENSG00000168781 ENSG00000176095 ENSG00000086544 ENSG00000151151 PMC8410881__F1 Alzheimer's disease alters oligodendrocytic glycolytic and ketolytic gene expression ENSG00000171105 ENSG00000067057 ENSG00000102104 ENSG00000159399 ENSG00000152556 PMC8121456__F2 CGAS-STING pathway: The role of self-DNA sensing in inflammatory lung disease ENSG00000183735 ENSG00000213928 ENSG00000164430 ENSG00000115415 PMC8121456__F1 CGAS-STING pathway: The role of self-DNA sensing in inflammatory lung disease ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000163568 ENSG00000125538 ENSG00000172936 ENSG00000276561 PMC11956211__F6 Apoptosis signaling pathway in KEGG ENSG00000188486 ENSG00000149311 ENSG00000162711 ENSG00000099985 ENSG00000137033 ENSG00000196839 ENSG00000083799 ENSG00000100504 ENSG00000168040 ENSG00000168404 ENSG00000143258 ENSG00000084774 PMC8745310__F1 Ubiquitin Signaling in Innate Immune Response by Herpesviruses ENSG00000135655 ENSG00000132109 ENSG00000183735 ENSG00000133874 ENSG00000088888 ENSG00000078747 ENSG00000165312 ENSG00000137699 ENSG00000121060 ENSG00000141569 ENSG00000101695 PMC8131930__F3 Aspergillus fumigatus and aspergillosis: From basics to clinics ENSG00000180210 ENSG00000166278 PMC8660704__F7 DCZ0014, a novel compound in the therapy of diffuse large B-cell lymphoma via the B cell receptor signaling pathway ENSG00000177455 ENSG00000135446 ENSG00000186716 ENSG00000198793 ENSG00000105810 ENSG00000168610 PMC10925712__F1 Schematic biosynthetic pathways of tocopherol and tocotrienol synthesis ENSG00000197429 PMC8745310__F3 Ubiquitin Signaling in Innate Immune Response by Herpesviruses ENSG00000185515 ENSG00000163568 ENSG00000163565 ENSG00000091592 ENSG00000170242 PMC8745310__F2 Ubiquitin Signaling in Innate Immune Response by Herpesviruses ENSG00000090432 ENSG00000183735 ENSG00000136878 ENSG00000164430 ENSG00000146063 ENSG00000119401 ENSG00000137699 ENSG00000083799 ENSG00000138942 ENSG00000169871 ENSG00000136014 PMC11674646__F1 Interactions and connections between the gut microbiota, metabolites, and cellular components with IBS ENSG00000106546 PMC8787237__F3 STING1 in sepsis: Mechanisms, functions, and implications ENSG00000164305 PMC11795048__F1 Design and application of A@HAP NPs in cancer therapy ENSG00000214285 ENSG00000189403 ENSG00000168610 PMC2376838__F8 LRG-Accelerated Differentiation Defines Unique G-CSFR Signaling Pathways Downstream of PU.1 and C/EBPE That Modulate Neutrophil Activation ENSG00000168610 PMC7181720__F1 Proteomic analysis of the OTULIN protein complex ENSG00000119401 ENSG00000091039 ENSG00000134644 ENSG00000017260 ENSG00000154124 ENSG00000159399 PMC5045091__F2 Modification of the HIF-mediated switch to anaerobic respiration in osteoclasts.Notes: Osteoclasts specifically increase flux through both the glycolytic pathway and mitochondrial ETC to provide ATP and ROS necessary for bone resorption ENSG00000114268 ENSG00000131196 PMC8955970__F1 Endometrial Cancer Stem Cells: Where Do We Stand and Where Should We Go? ENSG00000138798 ENSG00000198793 ENSG00000168036 PMC3546980__F7 Irradiated Riboflavin Diminishes the Aggressiveness of Melanoma In Vitro and In Vivo ENSG00000166813 ENSG00000198793 ENSG00000136997 ENSG00000164690 ENSG00000128602 PMC10559930__F1 Mechanism involved in ZNF703 including the signaling pathway, upstream regulation network and downstream targets ENSG00000136485 ENSG00000198793 ENSG00000196498 ENSG00000183779 ENSG00000139687 PMC10897204__F6 Newly identified APA-linked cancer susceptibility genes are enriched in metabolic reprogramming and apoptosis-related pathways ENSG00000152348 ENSG00000070193 ENSG00000168894 ENSG00000186141 ENSG00000124126 ENSG00000183765 ENSG00000012048 ENSG00000105808 ENSG00000291948 ENSG00000266173 ENSG00000113761 ENSG00000148400 ENSG00000139618 ENSG00000105771 ENSG00000005075 ENSG00000101194 ENSG00000198863 ENSG00000170632 ENSG00000167523 ENSG00000188820 ENSG00000141570 ENSG00000144445 ENSG00000149483 ENSG00000152219 ENSG00000198586 ENSG00000151327 ENSG00000140319 ENSG00000082146 ENSG00000213246 ENSG00000100410 ENSG00000119820 ENSG00000104093 ENSG00000118418 ENSG00000178927 ENSG00000285302 ENSG00000291971 ENSG00000271383 ENSG00000158517 ENSG00000169032 ENSG00000121879 ENSG00000129933 ENSG00000166263 ENSG00000171634 ENSG00000197912 ENSG00000026103 ENSG00000262788 ENSG00000023902 ENSG00000069329 ENSG00000115486 ENSG00000147454 ENSG00000164362 ENSG00000182534 ENSG00000125124 PMC8656491__F1 Impact of DNA Damage Response—Targeted Therapies on the Immune Response to Tumours ENSG00000143799 ENSG00000149311 ENSG00000291803 ENSG00000138385 PMC5803917__F4 AP1 and CEBP mediated skin barrier impairment by BM ENSG00000172216 ENSG00000010810 ENSG00000177606 ENSG00000026508 ENSG00000185591 ENSG00000036828 ENSG00000121879 ENSG00000124181 ENSG00000065243 PMC5803917__F3 TNF mediated anti-inflammatory effect of BM ENSG00000108691 ENSG00000145321 ENSG00000007908 PMC5803917__F6 Factors implicated in manifestation of disease during drug treatment ENSG00000173599 ENSG00000166501 ENSG00000139687 ENSG00000089159 PMC7882032__F4 Decline in biological resilience as key manifestation of aging: Potential mechanisms and role in health and longevity ENSG00000149311 ENSG00000175054 ENSG00000285069 ENSG00000080546 PMC8626541__F1 FA-BRCA Pathway ENSG00000131944 ENSG00000083093 ENSG00000144554 ENSG00000188827 ENSG00000077152 ENSG00000187790 ENSG00000051180 ENSG00000139618 PMC6493882__F2 Two potential grounds for attenuation of IFN‐B bioactivity by statins ENSG00000111537 ENSG00000115415 ENSG00000113520 PMC7498011__F5 Rps27a might act as a controller of microglia activation in triggering neurodegenerative diseases ENSG00000051523 ENSG00000150045 ENSG00000291971 ENSG00000125508 ENSG00000197272 ENSG00000161980 ENSG00000180424 ENSG00000150093 ENSG00000111321 ENSG00000104921 ENSG00000149295 ENSG00000108561 ENSG00000150782 ENSG00000102879 ENSG00000188313 ENSG00000263528 ENSG00000233816 ENSG00000113263 ENSG00000186652 ENSG00000162892 ENSG00000132109 ENSG00000204671 ENSG00000188389 ENSG00000186827 ENSG00000116489 ENSG00000243646 ENSG00000131323 ENSG00000049249 ENSG00000171608 PMC5206550__F1 Hypothetical representation of the link between the Hog1 MAPK and the lipid metabolic pathways activated in R ENSG00000163624 ENSG00000146005 PMC2808241__F7 Genomic Profiling of Messenger RNAs and MicroRNAs Reveals Potential Mechanisms of TWEAK-Induced Skeletal Muscle Wasting in Mice ENSG00000110330 ENSG00000197893 ENSG00000148400 ENSG00000197905 ENSG00000106483 ENSG00000087303 ENSG00000166407 ENSG00000143631 ENSG00000264424 ENSG00000175130 ENSG00000187957 ENSG00000074800 ENSG00000291507 ENSG00000117122 ENSG00000074181 ENSG00000163207 ENSG00000177606 ENSG00000136997 ENSG00000165887 ENSG00000164708 ENSG00000108344 ENSG00000155657 ENSG00000188783 ENSG00000109670 PMC12133740__F1 Integrated schematic of glycolysis, mitochondrial metabolism, and lipid pathways in NSCLC cells ENSG00000169710 ENSG00000159399 ENSG00000060762 PMC3703418__F2 Cellular mechanisms of BBR in reverting dysfunction in NAFLD ENSG00000171105 PMC12133740__F3 Targetable metabolic pathways and inhibitors in NSCLC ENSG00000131473 ENSG00000198793 ENSG00000169710 ENSG00000135069 ENSG00000138074 ENSG00000099194 ENSG00000103257 ENSG00000146733 ENSG00000168003 ENSG00000092621 ENSG00000136997 ENSG00000118520 ENSG00000036473 ENSG00000146648 ENSG00000026103 PMC4935775__F1 Na+-Cl− cotransporter (NCC) regulation by the cullin-3 (CUL3)/kelch-like 3 (KLHL3)-with no lysine (WNK)-STE20/SPS-1-related proline/alanine-rich kinase (SPAK)/oxidative stress response kinase (OSR1) pathway ENSG00000143867 ENSG00000146021 PMC10498649__F2 Lipid metabolic alterations induced by oncogenic events and TME cues ENSG00000131473 ENSG00000135218 ENSG00000136997 ENSG00000169710 PMC3671288__F2 Inhibitory pathway of PGE2 in effector T cells ENSG00000049768 PMC3671288__F1 General overview of synthesis pathways for eicosanoids ENSG00000173599 PMC8703113__F3 Caveolin-1 Regulates Cellular Metabolism: A Potential Therapeutic Target in Kidney Disease ENSG00000198793 PMC9017014__F1 Dysregulation of Wnt signaling in bone of type 2 diabetes mellitus and diabetic Charcot arthropathy ENSG00000154342 ENSG00000162337 PMC3871639__F5 Inflammation Regulates TMPRSS6 Expression via STAT5 ENSG00000170365 ENSG00000187045 ENSG00000168610 PMC9266358__F8 Transcriptomic and Metabolomic Analysis of Quality Changes during Sweet Cherry Fruit Development and Mining of Related Genes ENSG00000131473 ENSG00000140263 ENSG00000138030 ENSG00000084774 PMC3188880__F2 Stat3 interactions in glioma biology ENSG00000111537 ENSG00000099985 ENSG00000128342 ENSG00000168610 PMC6257835__F7 Involvement of circRNAs in the Hippo signaling pathway ENSG00000137713 ENSG00000105327 ENSG00000044115 ENSG00000134308 ENSG00000169884 ENSG00000156475 ENSG00000157240 ENSG00000148498 ENSG00000163251 ENSG00000078900 ENSG00000089685 ENSG00000163558 ENSG00000155760 ENSG00000107779 ENSG00000113645 ENSG00000134376 ENSG00000166167 ENSG00000138795 ENSG00000170027 ENSG00000109321 ENSG00000105568 ENSG00000143514 ENSG00000150672 ENSG00000169435 ENSG00000105329 ENSG00000221914 ENSG00000168036 ENSG00000118971 ENSG00000186575 ENSG00000116985 ENSG00000132535 ENSG00000125968 ENSG00000174804 ENSG00000139926 ENSG00000114978 ENSG00000153303 ENSG00000002745 ENSG00000007866 ENSG00000018408 ENSG00000150457 ENSG00000072803 ENSG00000131023 ENSG00000186298 ENSG00000074211 ENSG00000019549 ENSG00000104290 ENSG00000161202 ENSG00000168646 ENSG00000124171 ENSG00000204217 ENSG00000178184 PMC6257835__F6 Involvement of circRNAs in the ErbB signaling pathway ENSG00000185634 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000115904 ENSG00000108443 ENSG00000105647 ENSG00000169032 ENSG00000099942 ENSG00000100485 ENSG00000121879 ENSG00000124762 ENSG00000175634 ENSG00000148082 ENSG00000149269 ENSG00000166501 ENSG00000071051 ENSG00000197943 ENSG00000137843 ENSG00000157764 ENSG00000065361 ENSG00000109321 ENSG00000113070 ENSG00000158458 ENSG00000065559 ENSG00000169752 ENSG00000160691 ENSG00000117020 ENSG00000110395 ENSG00000148660 ENSG00000163235 ENSG00000124882 ENSG00000173757 ENSG00000177606 ENSG00000143322 ENSG00000146648 ENSG00000145349 ENSG00000130669 ENSG00000178568 PMC8438979__F4 UHPLC-MS-MS analysis of oxylipins metabolomics components of follicular fluid in infertile individuals with diminished ovarian reserve ENSG00000226275 PMC5737940__F2 Cellular signaling pathways through which NELL-1 works ENSG00000281324 ENSG00000106571 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000128602 PMC10887358__F2 Signaling pathways of B cell receptor (BCR) ENSG00000095585 ENSG00000105369 ENSG00000007312 ENSG00000010810 ENSG00000186716 ENSG00000197943 PMC12154347__F7 Dihydrocapsaicin Enhances Tumor Necrosis Factor-Alpha-Induced Apoptosis and G1 Cell Cycle Arrest in Human Cervical Cancer Cells Through TAK1-Mediated NFKB and EGFR Pathways ENSG00000146648 PMC8610843__F3 Endothelial contribution to COVID-19: an update on mechanisms and therapeutic implications ENSG00000162711 ENSG00000107562 ENSG00000291971 ENSG00000130234 ENSG00000168036 ENSG00000189403 ENSG00000136869 ENSG00000112715 PMC7320752__F6 Protein interaction pathway analysis in metastasis ENSG00000135547 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000288145 ENSG00000188064 ENSG00000169884 ENSG00000146143 ENSG00000198056 ENSG00000100485 ENSG00000124762 ENSG00000175634 ENSG00000163251 ENSG00000082175 ENSG00000148082 ENSG00000076043 ENSG00000014138 ENSG00000116030 ENSG00000188612 ENSG00000184900 ENSG00000155760 ENSG00000140443 ENSG00000282899 ENSG00000138795 ENSG00000151461 ENSG00000120211 ENSG00000107295 ENSG00000198176 ENSG00000140285 ENSG00000100479 ENSG00000004975 ENSG00000115904 ENSG00000196468 ENSG00000105647 ENSG00000169032 ENSG00000121879 ENSG00000077150 ENSG00000092621 ENSG00000129946 ENSG00000123374 ENSG00000185591 ENSG00000154310 ENSG00000037280 ENSG00000089289 ENSG00000118972 ENSG00000119541 ENSG00000157764 ENSG00000142230 ENSG00000277641 ENSG00000065328 ENSG00000117020 ENSG00000135446 ENSG00000156427 ENSG00000177606 ENSG00000161202 ENSG00000070193 ENSG00000154764 ENSG00000157404 ENSG00000181274 ENSG00000108443 ENSG00000141068 ENSG00000112118 ENSG00000091651 ENSG00000073111 ENSG00000163960 ENSG00000076003 ENSG00000102678 ENSG00000125084 ENSG00000166508 ENSG00000012048 ENSG00000105325 ENSG00000084676 ENSG00000128917 ENSG00000143222 ENSG00000074181 ENSG00000136997 ENSG00000105810 ENSG00000177283 ENSG00000077782 ENSG00000139687 ENSG00000276799 ENSG00000162552 ENSG00000107404 ENSG00000148400 ENSG00000292149 ENSG00000169756 ENSG00000139618 ENSG00000134574 ENSG00000162692 ENSG00000146648 ENSG00000100711 ENSG00000070388 ENSG00000103494 ENSG00000185634 ENSG00000128951 ENSG00000105550 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000288422 ENSG00000132485 ENSG00000166140 ENSG00000061492 ENSG00000129351 ENSG00000129187 ENSG00000148426 ENSG00000152359 ENSG00000141580 ENSG00000112242 ENSG00000115942 ENSG00000165879 ENSG00000111186 ENSG00000135336 ENSG00000139970 ENSG00000177084 ENSG00000154342 ENSG00000077721 ENSG00000002745 ENSG00000132478 ENSG00000184916 ENSG00000090932 ENSG00000119048 ENSG00000160691 ENSG00000078579 ENSG00000115266 ENSG00000273529 ENSG00000171608 ENSG00000114315 ENSG00000115232 ENSG00000175305 PMC5518631__F1 Agrin signaling and YAP in neuromuscular junction formation (NMJ) and liver cancer development ENSG00000134569 ENSG00000030304 PMC7191280__F1 SARS-CoV-2 receptor ACE2-dependent implications on the cardiovascular system: From basic science to clinical implications ENSG00000175054 ENSG00000111537 ENSG00000130234 ENSG00000184012 PMC7086350__F1 DDR core gene amplification across pan-cancer ENSG00000012061 ENSG00000143799 ENSG00000104884 ENSG00000083093 ENSG00000178295 ENSG00000154920 ENSG00000077152 ENSG00000067369 ENSG00000064933 ENSG00000183765 ENSG00000012048 ENSG00000134899 ENSG00000175054 ENSG00000189046 ENSG00000181625 ENSG00000079246 ENSG00000101773 ENSG00000144554 ENSG00000148229 ENSG00000113318 ENSG00000104320 ENSG00000170430 ENSG00000101654 ENSG00000139372 ENSG00000051180 ENSG00000177084 ENSG00000166169 ENSG00000253729 ENSG00000164053 ENSG00000136492 ENSG00000166199 ENSG00000181544 ENSG00000187790 ENSG00000115392 ENSG00000130997 ENSG00000187741 ENSG00000158169 ENSG00000139618 ENSG00000149311 ENSG00000197299 ENSG00000149554 ENSG00000187736 ENSG00000095002 ENSG00000042088 ENSG00000122678 ENSG00000122512 ENSG00000009413 PMC8130467__F5 Improved COVID-19 ICU admission and mortality outcomes following treatment with statins: a systematic review and meta-analysis ENSG00000110799 ENSG00000130234 ENSG00000184012 ENSG00000172936 PMC3594545__F2 Regulation of NFKB by Ubiquitination ENSG00000183735 ENSG00000088888 ENSG00000121060 PMC3594545__F1 Regulation of NFKB by Ubiquitination ENSG00000125538 ENSG00000157625 ENSG00000175104 PMC6779827__F2 Innate immune pathways inhibition by calicivirus infection ENSG00000101981 PMC8105803__F7 Map of p53 signaling pathway regulated by LEP gene drawn through the KEGG database ENSG00000002330 ENSG00000186716 ENSG00000136869 PMC8105803__F6 Map of PI3K/AKT/mTOR signaling pathway regulated by the LEP gene drawn through the KEGG database ENSG00000149311 ENSG00000132906 ENSG00000175054 ENSG00000136997 ENSG00000042286 ENSG00000112378 PMC6311566__F1 Overview of metabolic pathways implicated in epigenetic modifications in NSC ENSG00000096717 PMC8902310__F3 Type I Interferon Responses to Influence Tumor-Immune Cross Talk in PDAC ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000197594 ENSG00000131323 ENSG00000164342 PMC4914279__F8 Epidermal growth factor receptor regulates cofilin activity and promotes transmissible gastroenteritis virus entry into intestinal epithelial cells ENSG00000070831 ENSG00000067900 ENSG00000146648 PMC3361682__F2 UCB interaction with neural plasma membrane (A) and pathways by which UCB may affect neuronal function (B) ENSG00000113600 ENSG00000127191 PMC4935960__F6 Independent Tumor Origin in Two Cases of Synchronous Bilateral Clear Cell Renal Cell Carcinoma ENSG00000070193 ENSG00000170365 ENSG00000134086 ENSG00000140367 ENSG00000198793 ENSG00000128602 ENSG00000146648 ENSG00000126012 ENSG00000123124 PMC6678135__F7 Compounds that inhibit and activate autophagy ENSG00000177169 ENSG00000152348 ENSG00000198382 ENSG00000083290 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC8446193__F2 Murine Models Provide New Insights Into Pathogenesis of Chronic Graft-Versus-Host Disease in Humans ENSG00000134982 ENSG00000168610 ENSG00000135605 PMC6538418__F1 Key players in autophagosome formation ENSG00000177169 ENSG00000083290 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000171791 ENSG00000145782 ENSG00000057663 PMC11356322__F3 Metabolic pathway interaction network of Cluster-0 metabolite (4-hydroxybenzoic acid) ENSG00000119723 ENSG00000110871 ENSG00000196502 ENSG00000088682 ENSG00000104549 ENSG00000148459 ENSG00000173085 PMC7002700__F5 Schematic showing the signaling pathway of miR-125a-3p- Fyn–NRP1 interaction by TNFA in DPSCs ENSG00000010810 ENSG00000168036 ENSG00000152591 PMC5642637__F2 miR-708-5p: a microRNA with emerging roles in cancer ENSG00000053438 ENSG00000026508 ENSG00000186432 PMC6788064__F2 Signaling pathways participating in the function of cadherins in cancer ENSG00000134982 ENSG00000170558 PMC8610843__F1 Endothelial contribution to COVID-19: an update on mechanisms and therapeutic implications ENSG00000130234 ENSG00000184012 PMC9652569__F5 Hedysarum multijugum Maxim treats ulcerative colitis through the PI3K-AKT and TNF signaling pathway according to network pharmacology and molecular docking ENSG00000138798 ENSG00000140505 ENSG00000124107 ENSG00000171791 ENSG00000145386 ENSG00000112715 ENSG00000164305 ENSG00000124762 ENSG00000106546 ENSG00000183765 ENSG00000112038 ENSG00000149968 ENSG00000128052 ENSG00000136997 ENSG00000125538 ENSG00000166501 ENSG00000169429 ENSG00000113520 ENSG00000139687 ENSG00000132906 ENSG00000087245 ENSG00000104365 ENSG00000081041 ENSG00000115008 ENSG00000100906 ENSG00000131747 ENSG00000173039 ENSG00000007908 ENSG00000213341 ENSG00000257335 ENSG00000140465 ENSG00000132693 ENSG00000007171 ENSG00000169245 ENSG00000108691 ENSG00000111537 ENSG00000118785 ENSG00000102245 ENSG00000177606 ENSG00000100985 ENSG00000005381 ENSG00000149554 ENSG00000146648 PMC6197473__F2 Snapshot of protein-protein interactions involving p85A (the “p85A network”).The binding to PTEN and to BRD7-XBP1 has a negative effect on PI3K activity (red color), the first by stabilizing PTEN, the second via p85A depletion (, , –) ENSG00000070831 ENSG00000100219 ENSG00000166164 PMC6179164__F6 Mechanisms by which IFNA disrupts thyrocytes to trigger AITDs ENSG00000132109 ENSG00000169245 ENSG00000042832 PMC9652569__F1 Hedysarum multijugum Maxim treats ulcerative colitis through the PI3K-AKT and TNF signaling pathway according to network pharmacology and molecular docking ENSG00000100906 ENSG00000111837 ENSG00000177606 ENSG00000173039 PMC9639746__F1 Cancer immunotherapy strategies that target the cGAS-STING pathway ENSG00000164430 ENSG00000134982 ENSG00000121058 PMC9652569__F7 Hedysarum multijugum Maxim treats ulcerative colitis through the PI3K-AKT and TNF signaling pathway according to network pharmacology and molecular docking ENSG00000177606 ENSG00000173039 PMC12141126__F2 Systemic lupus erythematosus-induced endothelial dysfunction and atherosclerosis ENSG00000110799 ENSG00000162692 ENSG00000132693 PMC3946543__F4 A Lipidomic Perspective on Inflammatory Macrophage Eicosanoid Signaling ENSG00000166278 PMC7327152__F1 Deciphering Macrophage Phenotypes upon Lipid Uptake and Atherosclerosis ENSG00000162711 ENSG00000108691 ENSG00000135218 ENSG00000111537 ENSG00000115415 ENSG00000137077 ENSG00000125538 ENSG00000172936 ENSG00000160179 ENSG00000162692 ENSG00000121807 PMC8070608__F2 Plasmin and Plasminogen System in the Tumor Microenvironment: Implications for Cancer Diagnosis, Prognosis, and Therapy ENSG00000176692 ENSG00000105329 ENSG00000198793 ENSG00000122194 ENSG00000140464 PMC8563889__F1 Ferroptosis, radiotherapy, and combination therapeutic strategies ENSG00000228716 ENSG00000149311 ENSG00000128272 ENSG00000151012 ENSG00000197429 ENSG00000111684 ENSG00000099194 ENSG00000127948 PMC7829660__F3 Natural and synthetic carbohydrate-based vaccine adjuvants and their mechanisms of action ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC9630482__F2 Extracellular vesicles as advanced therapeutics for the resolution of organ fibrosis: Current progress and future perspectives ENSG00000170365 ENSG00000168036 PMC10816780__F15 Transgenerational Transmission of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Effects in Human Granulosa Cells: The Role of MicroRNAs ENSG00000136997 ENSG00000171791 ENSG00000168610 ENSG00000026103 ENSG00000150630 PMC5545727__F3 List of 24 CMMDh genes (left), genes enriched to the top canonical signaling pathways (middle) and the network of these genes with mood disorders and the CMD-Rs (right) ENSG00000084093 ENSG00000150594 ENSG00000134640 ENSG00000130287 ENSG00000115138 ENSG00000136869 ENSG00000055955 ENSG00000036565 ENSG00000043591 ENSG00000087460 PMC7804279__F2 The Hippo pathway in the pathogenesis of inflammatory bowel disease ENSG00000150457 ENSG00000131023 PMC7804279__F1 The Hippo pathway in the pathogenesis of inflammatory bowel disease ENSG00000186575 ENSG00000144560 ENSG00000150457 ENSG00000131023 PMC7804279__F4 The Hippo pathway in the pathogenesis of inflammatory bowel disease ENSG00000150457 ENSG00000112715 ENSG00000131023 PMC7804279__F3 The Hippo pathway in the pathogenesis of inflammatory bowel disease ENSG00000049768 ENSG00000168610 PMC8803653__F2 Rituximab in the Treatment of Interstitial Lung Diseases Related to Anti-Melanoma Differentiation-Associated Gene 5 Dermatomyositis: A Systematic Review ENSG00000121966 PMC8232320__F1 Monogenic Autoinflammatory Diseases: State of the Art and Future Perspectives ENSG00000101868 ENSG00000162711 ENSG00000150782 ENSG00000110921 ENSG00000164430 ENSG00000167207 ENSG00000172922 ENSG00000125538 ENSG00000136869 ENSG00000154124 ENSG00000102172 PMC3989450__F3 Wnt-dependent interactions between cardiac myocytes and cardiac fibroblasts after acute myocardial infarction ENSG00000154342 ENSG00000168036 ENSG00000106483 ENSG00000104332 ENSG00000125084 PMC5346041__F1 Major pattern recognition receptors (PRRs) that sense RNA and DNA virus pathogen associated molecular patterns (PAMPs) in the cytosol ENSG00000094631 ENSG00000164430 ENSG00000088888 ENSG00000163568 ENSG00000163565 ENSG00000121060 PMC3989450__F2 Canonical Wnt signalling ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4485953__F2 New Model of Reverse Cholesterol Transport: EnTICEing Strategies to Stimulate Intestinal Cholesterol Excretion ENSG00000138075 ENSG00000130164 ENSG00000015520 ENSG00000120437 ENSG00000169174 ENSG00000143921 PMC3620567__F1 Ischemia-reperfusion injury in the diabetic myocardium is multi-factorial and complex ENSG00000002330 PMC10379778__F2 ARHGAP1 in Rho GTPase Inactivation during Metastasizing of Breast Cancer Cell Line MCF-7 after Treatment with Doxorubicin ENSG00000151276 ENSG00000138795 ENSG00000070831 ENSG00000291971 ENSG00000134982 ENSG00000140575 ENSG00000170558 ENSG00000168036 PMC10379778__F1 ARHGAP1 in Rho GTPase Inactivation during Metastasizing of Breast Cancer Cell Line MCF-7 after Treatment with Doxorubicin ENSG00000100811 ENSG00000140992 ENSG00000137834 ENSG00000005339 ENSG00000157764 ENSG00000070831 ENSG00000134982 ENSG00000095015 ENSG00000115904 ENSG00000099860 ENSG00000067900 ENSG00000135341 ENSG00000160691 ENSG00000136603 ENSG00000105325 ENSG00000172216 ENSG00000149269 ENSG00000102981 ENSG00000177606 ENSG00000185591 ENSG00000175104 PMC6691199__F3 Proposed pathophysiological mechanisms that could explain the presence or absence of response to treatment in myocarditis ENSG00000125538 ENSG00000151929 ENSG00000198626 ENSG00000057294 PMC9405832__F1 MTHFR SNPs (Methyl Tetrahydrofolate Reductase, Single Nucleotide Polymorphisms) C677T and A1298C Prevalence and Serum Homocysteine Levels in >2100 Hypofertile Caucasian Male Patients ENSG00000228716 PMC5638334__F10 De novo transcriptome sequencing of Isaria cateniannulata and comparative analysis of gene expression in response to heat and cold stresses ENSG00000115561 ENSG00000165527 PMC12065808__F1 Comprehensive network featuring genetic regulation and glucose, fatty acid, and glutamine metabolism in cancer ENSG00000131473 ENSG00000135423 ENSG00000135218 ENSG00000198793 ENSG00000173599 ENSG00000136997 ENSG00000062485 ENSG00000026103 PMC4537692__F8 Angiotensin II Induces Skeletal Muscle Atrophy by Activating TFEB-Mediated MuRF1 Expression ENSG00000008710 ENSG00000112561 ENSG00000108840 PMC9293965__F2 Clusters of significantly enriched biological pathways for AD and GERD ENSG00000275111 ENSG00000018869 PMC11791101__F3 Paracrine of the hedgehog signaling pathway ENSG00000180447 ENSG00000117425 ENSG00000144857 ENSG00000166813 ENSG00000171791 ENSG00000128602 ENSG00000118971 PMC11791101__F2 Autocrine of the hedgehog signaling pathway ENSG00000180447 ENSG00000117425 ENSG00000144857 ENSG00000166813 ENSG00000171791 ENSG00000112715 ENSG00000128602 ENSG00000118971 PMC11791101__F1 Normal activation mechanism of hedgehog signaling pathway ENSG00000180447 ENSG00000106571 ENSG00000173040 ENSG00000117425 ENSG00000166813 ENSG00000128602 PMC4344782__F9 Alzheimer-related protein association network in AD-iPS5 neurons ENSG00000142192 ENSG00000169021 ENSG00000147684 ENSG00000073578 ENSG00000117118 ENSG00000143933 ENSG00000004779 ENSG00000164305 ENSG00000165264 ENSG00000178127 ENSG00000120910 ENSG00000131174 ENSG00000205155 ENSG00000189043 ENSG00000099795 ENSG00000119013 PMC6047437__F1 Genetic biomarkers of drug response for small-molecule therapeutics targeting the RTK/Ras/PI3K, p53 or Rb pathway in glioblastoma ENSG00000157764 ENSG00000198793 ENSG00000274089 ENSG00000146648 PMC4631295__F2 Canonical Wnt signaling pathway ENSG00000134982 ENSG00000168036 PMC5536816__F3 Benefits of physical exercise (PE) act through or require a healthy, functional endothelium (beige cells) ENSG00000168036 ENSG00000162692 ENSG00000142082 PMC6985271__F1 Type-I interferon signaling and ISG15 ENSG00000184979 ENSG00000145604 ENSG00000187608 ENSG00000105397 ENSG00000142166 PMC9025460__F1 Exploring Thermal Sensitivities and Adaptations of Oxidative Phosphorylation Pathways ENSG00000137767 ENSG00000100033 ENSG00000102967 PMC5088510__F3 Proteins modified by lysine methylation from the PhosphoSitePlus database were mapped onto the Kyoto Encyclopedia of Genes and Genomes (KEGG) prostate cancer pathway ENSG00000277893 ENSG00000198793 ENSG00000168036 ENSG00000123374 ENSG00000171791 PMC4129668__F1 Roles of PGs/GAGs on the breast cancer motile phenotype ENSG00000291971 ENSG00000146648 PMC5342467__F9 RGS6 is an essential tumor suppressor that prevents bladder carcinogenesis by promoting p53 activation and DNMT1 downregulation ENSG00000149311 ENSG00000178028 PMC8110983__F2 Tumour-derived factors associated with cachexia in pancreatic adenocarcinoma ENSG00000125538 ENSG00000198793 ENSG00000115138 ENSG00000168610 PMC10275075__F5 Population response of intestinal microbiota to acute Vibrio alginolyticus infection in half-smooth tongue sole (Cynoglossus semilaevis) ENSG00000151702 ENSG00000182263 PMC7840052__F7 Chinese wolfberry and Astragalus extract on the antioxidant capacity of Tibetan pig liver ENSG00000142655 ENSG00000176894 ENSG00000124587 ENSG00000157911 ENSG00000101417 ENSG00000108733 ENSG00000150787 ENSG00000164751 ENSG00000162928 ENSG00000121680 PMC7072125__F8 Molecular regulatory mechanism of Wnt/Beta-catenin signaling, induction of extrinsic apoptosis pathway by natural bioactive TA in NCCIT cells, and role of mROS in TRAIL-mediated extrinsic apoptosis induction with TA treatment ENSG00000102871 ENSG00000168036 PMC7072296__F2 Regulatory models of the Nrf2-ARE pathway induced by arsenic ENSG00000100387 ENSG00000079999 PMC8071157__F4 MicroRNAs involved in aromatase regulation in breast cancer ENSG00000168036 PMC8071157__F3 MicroRNAs involved in aromatase regulation in breast cancer ENSG00000198793 PMC8886228__F2 Metabolic Reprogramming, Gut Dysbiosis, and Nutrition Intervention in Canine Heart Disease ENSG00000135218 PMC12227620__F8 Graphical representation of the working model ENSG00000026508 ENSG00000168036 ENSG00000046604 PMC2966484__F3 Activation of the NFKB signaling pathway ENSG00000100387 ENSG00000113558 PMC6206851__F1 Cellular Mechanisms of Estrogen Action ENSG00000138798 ENSG00000177606 ENSG00000145321 ENSG00000129514 PMC6745301__F2 MicroRNAs and Regeneration in the Animal Models of CNS Disorders ENSG00000170365 ENSG00000164327 PMC6383596__F2 Effector cytokines can stimulate transcription of proinflammatory signals through the Janus kinase–signal transducers and activators of transcription (JAK-STAT) signalling pathway ENSG00000105397 ENSG00000105639 PMC2762102__F5 Tim–Tipin dysfunction creates an indispensible reliance on the ATR–Chk1 pathway for continued DNA synthesis ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000132646 ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000166508 PMC5038225__F1 IGF-1R downstream signaling cascades ENSG00000169047 ENSG00000198793 ENSG00000168610 ENSG00000140443 PMC3553500__F7 NleB, a bacterial effector with glycosyltransferase activity targets GADPH function to inhibit NFKB activation ENSG00000102871 ENSG00000127191 PMC9456096__F10 Metal Ion Periplasmic-Binding Protein YfeA of Glaesserella parasuis Induces the Secretion of Pro-Inflammatory Cytokines of Macrophages via MAPK and NFKB Signaling through TLR2 and TLR4 ENSG00000172005 ENSG00000172936 ENSG00000175104 PMC2909548__F4 Protein-protein interaction maps comprising the transforming growth factor B signaling pathway of transcription factors associated with liver cell proliferation ENSG00000133884 ENSG00000128272 ENSG00000182158 ENSG00000112245 ENSG00000100906 ENSG00000162772 ENSG00000283060 ENSG00000088038 ENSG00000166526 PMC2909548__F3 Protein-protein interaction comprising the transforming growth factor B signaling pathway ENSG00000125834 ENSG00000110429 ENSG00000109113 ENSG00000172007 ENSG00000213341 ENSG00000169242 ENSG00000166266 ENSG00000131941 ENSG00000108518 ENSG00000204262 ENSG00000141232 ENSG00000115956 ENSG00000177606 ENSG00000284099 ENSG00000291748 ENSG00000072422 ENSG00000133818 PMC5507649__F2 Targeting the ALK signaling pathway ENSG00000105894 ENSG00000115808 ENSG00000168610 PMC4516574__F5 An unexpected inhibition of antiviral signaling by virus-encoded tumor suppressor p53 in pancreatic cancer cells ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000089127 ENSG00000115415 ENSG00000033800 ENSG00000185745 ENSG00000185885 ENSG00000125347 ENSG00000230034 PMC6799822__F7 Signaling pathways contributing to mucus production ENSG00000291363 ENSG00000016490 ENSG00000185591 ENSG00000114315 ENSG00000146648 PMC6531857__F4 Regulated necrosis: disease relevance and therapeutic opportunities ENSG00000167468 ENSG00000116761 ENSG00000115419 PMC3862456__F3 Neutral AA transporters and activation of the mTORC1 signaling pathway ENSG00000169047 PMC6531857__F1 Regulated necrosis: disease relevance and therapeutic opportunities ENSG00000115008 ENSG00000137275 ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC4204437__F1 Fanconi anemia (FA) proteins implicated in interstrand cross-link (ICL) repair ENSG00000012048 ENSG00000188827 ENSG00000108384 PMC6913815__F1 An overview of the 3 unfolded protein response pathways ENSG00000128272 ENSG00000144895 ENSG00000105516 ENSG00000100219 ENSG00000162772 ENSG00000127191 PMC8799033__F3 Identification of key biomarkers and potential signaling pathway associated with poor progression of gastric cancer ENSG00000118785 ENSG00000111799 ENSG00000113140 ENSG00000108821 ENSG00000105669 PMC4938382__F2 Whole Genome Pathway Analysis Identifies an Association of Cadmium Response Gene Loss with Copy Number Variation in Mutant p53 Bearing Uterine Endometrial Carcinomas ENSG00000156642 ENSG00000134982 ENSG00000158856 ENSG00000138621 ENSG00000205362 ENSG00000136826 ENSG00000069667 ENSG00000159167 ENSG00000157890 ENSG00000125144 ENSG00000291669 ENSG00000038427 ENSG00000179772 ENSG00000147896 ENSG00000113263 ENSG00000291355 ENSG00000145708 ENSG00000140263 ENSG00000113140 ENSG00000073712 ENSG00000109738 ENSG00000081189 ENSG00000102287 ENSG00000164326 ENSG00000157766 ENSG00000168484 ENSG00000291649 PMC8799033__F6 Identification of key biomarkers and potential signaling pathway associated with poor progression of gastric cancer ENSG00000136457 ENSG00000135218 ENSG00000110799 ENSG00000026508 PMC7601648__F1 Canonical NFKB signalling pathway induced by TNFA and IL-1B and the role of ubiquitination ENSG00000123091 ENSG00000181788 ENSG00000113595 ENSG00000102871 ENSG00000120913 ENSG00000127191 ENSG00000103404 ENSG00000136878 ENSG00000078747 ENSG00000111653 ENSG00000090686 ENSG00000172936 ENSG00000083799 ENSG00000175104 ENSG00000143258 ENSG00000184216 PMC4160340__F2 Rho-GTPases as key regulators of T lymphocyte biology ENSG00000291603 ENSG00000213658 ENSG00000070831 ENSG00000134982 ENSG00000163914 ENSG00000124181 ENSG00000141968 PMC3730427__F8 Glucose deprivation in cancer cells activates UPR following HBP flux reduction ENSG00000128272 ENSG00000100219 ENSG00000171791 PMC4601190__F2 Epithelial cell recognition and discrimination of Candida albicans yeast and hyphae ENSG00000198793 PMC11586749__F6 Analysis of classical signaling pathways and immune infiltration ENSG00000019485 ENSG00000160789 ENSG00000166477 ENSG00000147133 ENSG00000108654 ENSG00000129514 ENSG00000088038 ENSG00000136826 ENSG00000196628 ENSG00000107077 ENSG00000136807 ENSG00000151702 ENSG00000245848 ENSG00000170365 ENSG00000141867 ENSG00000125398 ENSG00000172216 ENSG00000082175 ENSG00000150907 ENSG00000136997 ENSG00000137203 ENSG00000125686 ENSG00000188612 ENSG00000077782 ENSG00000179348 ENSG00000120837 ENSG00000100888 ENSG00000125347 ENSG00000106459 ENSG00000174720 ENSG00000166478 ENSG00000175745 ENSG00000156127 ENSG00000198517 ENSG00000067955 ENSG00000122779 ENSG00000132964 ENSG00000121060 ENSG00000130726 ENSG00000157554 ENSG00000087510 ENSG00000028277 ENSG00000178951 ENSG00000001167 ENSG00000020633 ENSG00000164190 ENSG00000277273 ENSG00000099381 ENSG00000008083 ENSG00000106546 ENSG00000077150 ENSG00000171456 ENSG00000172534 ENSG00000171634 ENSG00000090447 ENSG00000004487 ENSG00000137265 ENSG00000196235 ENSG00000185591 ENSG00000100811 ENSG00000118058 ENSG00000071655 ENSG00000143390 ENSG00000005339 ENSG00000140262 ENSG00000173575 ENSG00000108055 ENSG00000109320 ENSG00000066135 ENSG00000154832 ENSG00000168610 ENSG00000291420 ENSG00000139352 ENSG00000071564 ENSG00000165632 ENSG00000183337 ENSG00000115415 ENSG00000177606 ENSG00000019549 ENSG00000105610 ENSG00000164754 ENSG00000126353 ENSG00000074266 ENSG00000167182 ENSG00000089902 ENSG00000102974 PMC7609400__F2 Extrinsic function of the PD-1/PD-L1 signaling axis in cancer ENSG00000291603 ENSG00000213658 ENSG00000134982 PMC7444376__F3 GCN5 enhances the osteogenic differentiation of PDLSCs ENSG00000281324 ENSG00000162337 ENSG00000183762 ENSG00000168036 PMC10571700__F5 Gene expression (CAMs) ENSG00000291603 ENSG00000169896 ENSG00000197471 ENSG00000198851 ENSG00000138798 ENSG00000163599 ENSG00000170558 ENSG00000021645 ENSG00000188389 ENSG00000123685 ENSG00000168062 ENSG00000117020 ENSG00000111537 ENSG00000018236 ENSG00000213658 ENSG00000110076 ENSG00000181847 ENSG00000154654 ENSG00000171608 ENSG00000146648 PMC8557044__F1 Ferroptosis: Opportunities and Challenges in Myocardial Ischemia-Reperfusion Injury ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000115107 PMC7477662__F1 Main signaling pathways regulating autophagy PMC7659517__F2 Schematic view of M1 and M2 macrophage metabolism.Left side, M1 macrophage triggers a pro-inflammatory response ENSG00000131473 ENSG00000135218 ENSG00000198793 ENSG00000162772 ENSG00000115419 PMC7659517__F1 Warburg effect likely supports replication of SARS CoV2 in airway cells.Enhanced aerobic glycolysis sustains the replication of many viruses in a similar way to the Warburg effect ENSG00000131473 ENSG00000130234 PMC6761220__F3 Strategies for immunomodulation to mitigate periprosthetic osteolysis induced by wear particles ENSG00000177575 ENSG00000125538 ENSG00000172936 ENSG00000118520 PMC4373664__F1 Canonical Rho GTPase signaling motifs regulate actin cytoskeletal dynamics ENSG00000070831 ENSG00000100592 ENSG00000149269 ENSG00000184922 PMC4644376__F12 Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression ENSG00000109321 ENSG00000163235 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC6664079__F3 Potential targets for immune modulation during chronic progression of implant-related bone infections ENSG00000089692 ENSG00000181847 ENSG00000163599 PMC10910037__F2 Crosstalk between NFKB signaling and other signaling pathways ENSG00000105369 ENSG00000134982 ENSG00000168036 ENSG00000172936 ENSG00000136869 ENSG00000168685 PMC5285449__F1 Hippo Signaling in the Liver Regulates Organ Size, Cell Fate, and Carcinogenesis ENSG00000126016 ENSG00000186575 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC5422478__F4 Autoantibodies in the pathogenesis of Graves’ orbitopathy ENSG00000169047 ENSG00000198793 ENSG00000165409 ENSG00000140443 PMC7881399__F3 Sub-network including 12 hub-bottleneck nodes and two seeds of clusters 1 and 2 ENSG00000291363 ENSG00000115263 ENSG00000113520 ENSG00000169429 ENSG00000112715 ENSG00000073756 ENSG00000146648 ENSG00000163631 PMC7881399__F6 Action relationships including activation (green), inhibition (red), expression (yellow), and binding (blue) between the genes which were related to the determined biochemical pathways ENSG00000291363 ENSG00000169429 ENSG00000112715 ENSG00000146648 ENSG00000163631 PMC7881399__F5 Results of biochemical pathway analysis of hub-bottlenecks plus seeds of cluster-1 and 2 via ClueGO+CluePedia analysis ENSG00000291363 ENSG00000169429 ENSG00000112715 ENSG00000073756 ENSG00000146648 ENSG00000163631 PMC5858916__F7 Rotavirus infection ENSG00000166167 ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC5341901__F4 On metabolic reprogramming and tumor biology: A comprehensive survey of metabolism in breast cancer ENSG00000136997 ENSG00000115419 PMC5898751__F6 Phytohormone and MAPK signaling pathway ENSG00000069956 PMC6539695__F7 EGF and TPA mediated pathway to phosphorylate serines in the SCFBTRCP recognition site of PDCD4-protein in Huh7 hepatoma cells ENSG00000138798 ENSG00000198793 PMC7544845__F6 Druggable signaling cascades in vasculitogenic T cells ENSG00000291603 ENSG00000148400 ENSG00000114315 PMC7544845__F5 NOTCH signaling pathway in giant cell arteritis ENSG00000148400 ENSG00000114315 PMC11872466__F10 KEGG pathway enrichment analyses of screened compounds in the treatment of AD ENSG00000132906 ENSG00000142192 ENSG00000002330 ENSG00000162337 ENSG00000126775 ENSG00000134982 ENSG00000156026 ENSG00000198793 ENSG00000183691 ENSG00000148572 ENSG00000115310 ENSG00000168040 ENSG00000164305 ENSG00000291983 ENSG00000198435 ENSG00000273529 ENSG00000133961 ENSG00000114315 ENSG00000119912 PMC11567945__F1 Alterations of paracellular permeability in Alzheimer's disease (AD) patients and numerous AD models ENSG00000100985 ENSG00000171885 PMC4075250__F5 Ingenuity network analysis of differentially regulated labeled-pairs ENSG00000143761 ENSG00000197971 ENSG00000288174 ENSG00000136997 ENSG00000173786 ENSG00000167419 ENSG00000067715 ENSG00000119125 PMC5404269__F8 CYP2J2 and Its Metabolites EETs Attenuate Insulin Resistance via Regulating Macrophage Polarization in Adipose Tissue ENSG00000177606 ENSG00000118520 ENSG00000134716 PMC5321202__F1 CORM-2 influences IBA-1- and GFAP-positive cells and many nociceptive factors and signaling pathways as measured on day 7 after CCI ENSG00000162711 ENSG00000137496 PMC6539695__F4 Pathways of EGF mediated protein synthesis and PDCD4 degradation ENSG00000198793 PMC7862811__F1 PI3K/AKT signaling pathway activation and potential functions of LAPTM4B in cancers ENSG00000104341 PMC3402681__F1 Proposed mechanistic model on how SHARPIN regulates TNF-induced NFKB activation through linear ubiquitination-mediated mechanisms ENSG00000102871 ENSG00000173039 ENSG00000157625 ENSG00000127191 PMC6212953__F1 Hepatitis C Virus (HCV)-induced oncogenic signaling ENSG00000134982 ENSG00000080603 ENSG00000168610 ENSG00000146648 PMC7881399__F2 Cluster-2 including 19 nodes and 111 edges ENSG00000108849 ENSG00000143546 ENSG00000096395 ENSG00000115263 ENSG00000214285 ENSG00000110680 ENSG00000145777 PMC7881399__F1 Cluster-1 including 24 nodes and 176 edges ENSG00000146469 ENSG00000169429 ENSG00000136869 ENSG00000112715 ENSG00000131096 ENSG00000073756 ENSG00000146648 ENSG00000167701 PMC8635784__F5 Low Molecular Weight Heparin Improves the Inflammatory State of Acute Sinusitis Rats Through Inhibiting the TLR4-MyD88-NFKB Signaling Pathway ENSG00000172936 ENSG00000136869 ENSG00000184216 PMC2577715__F15 Notch, Wnt, and SHH signaling pathways ENSG00000106571 ENSG00000134982 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC7701056__F1 PI3K/Akt/mTOR pathway ENSG00000005882 ENSG00000155792 PMC4102824__F1 Flow diagram of the monoamine neurotransmitter biosynthesis pathway ENSG00000123454 ENSG00000141744 ENSG00000116096 PMC6386234__F1 Molecular pathways of cellular senescence ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000198793 ENSG00000123374 PMC4588145__F1 Fish nucleic acid PRR signaling pathways ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC7346763__F2 The transmembrane receptors for CSPGs and myelin-associated inhibitors and the signaling pathways downstream of two receptor protein tyrosine phosphatases (RPTPs) ENSG00000134982 PMC4348434__F2 Oxidative Krebs cycle ENSG00000157184 ENSG00000173599 ENSG00000115419 ENSG00000062485 PMC4098898__F2 Glutamate Metabolism and HIV-Associated Neurocognitive Disorders ENSG00000124102 ENSG00000115415 ENSG00000121966 PMC2864663__F5 Aging-related upregulation of NFKB signaling in VSMC ENSG00000104856 ENSG00000162692 PMC2864663__F4 Aging-related upregulation of AP-1 signaling in VSMC ENSG00000132646 ENSG00000177606 PMC4685044__F1 Signaling pathways activated by cytokine receptor binding ENSG00000136997 ENSG00000168610 PMC5147022__F1 MicroRNA biogenesis pathway genes polymorphisms and cancer risk: a systematic review and meta-analysis ENSG00000100697 ENSG00000092847 ENSG00000128191 ENSG00000113360 ENSG00000134698 ENSG00000123908 ENSG00000132341 PMC2930664__F1 One-Carbon Metabolism and Alzheimer’s Disease: Focus on Epigenetics ENSG00000124275 ENSG00000035928 ENSG00000116984 PMC3518570__F2 Energy Intake and Exercise as Determinants of Brain Health and Vulnerability to Injury and Disease PMC6859457__F7 The HPV18 pathway regulates Tim-3/galectin-9 through EZH2-H2K27me3-DNMT3A ENSG00000135077 ENSG00000168961 PMC8042688__F1 Biological interactions among the formaldehyde-related genes, a hematological malignancies, and b cell processes ENSG00000143799 ENSG00000188486 ENSG00000105329 ENSG00000181104 ENSG00000164399 ENSG00000273686 ENSG00000171791 ENSG00000187266 ENSG00000180644 ENSG00000112715 ENSG00000073756 ENSG00000164305 ENSG00000124762 ENSG00000149311 ENSG00000150782 ENSG00000108691 ENSG00000111537 ENSG00000125538 ENSG00000113520 ENSG00000136869 ENSG00000112115 ENSG00000162692 ENSG00000005381 ENSG00000026103 PMC4623426__F4 Regulation of Janus activated kinase (JAK)-Stat and nuclear factor kappa B (NFKB) signaling by TGFB through MKP-1 ENSG00000115415 ENSG00000102871 ENSG00000127191 PMC4623426__F3 Transforming growth factor B (TGFB) signaling pathways and aging PMC4623426__F5 Reciprocal regulation of TGFB and Jak-Stat signaling ENSG00000111537 ENSG00000115415 PMC11643850__F4 Protective Effects of Pungent Flavor Components in Neurodegenerative Diseases ENSG00000128272 ENSG00000100219 PMC11643850__F3 Signaling of Wnt and calcium ions through MCOLN: CUR can activate Wnt signaling way by increasing the stability of Beta-cyclin, leading to its accumulation in the cytoplasm ENSG00000134982 ENSG00000136997 ENSG00000112561 ENSG00000168036 PMC11643850__F2 Signaling pathways for the neuroprotective effects of CAP and CB: CAP acts on TRPV1 and activates the PI3K/AKT/mTOR signaling pathway, enhances the phagocytosis of microglia, and activates the promoter of BDNF ENSG00000198793 ENSG00000196689 PMC4222256__F8 Supposed mechanism of EVE-induced EMT ENSG00000198793 ENSG00000173083 ENSG00000164327 ENSG00000167965 ENSG00000186654 PMC3108840__F7 Functional pathway analysis of glycoproteins overexpressed in PC3-ML2 ENSG00000088888 ENSG00000133110 ENSG00000105135 ENSG00000148798 ENSG00000132874 ENSG00000100941 PMC3108840__F6 Functional pathway analysis of glycoproteins overexpressed in PC3-N2 ENSG00000173821 ENSG00000136891 ENSG00000176986 ENSG00000095319 ENSG00000198561 ENSG00000134910 ENSG00000196504 ENSG00000196352 ENSG00000099864 ENSG00000136167 PMC6689970__F1 Schematic overview of NAD biosynthesis pathways ENSG00000105835 ENSG00000123572 ENSG00000278488 PMC9554879__F5 Immunogenic cell death related risk model to delineate ferroptosis pathway and predict immunotherapy response of patients with GBM ENSG00000105656 PMC2270353__F4 NPTX2 pathway obtained by means of the Resnet 5.0 eukaryotic database of molecular interactions (Ariadne) overlayed with microarray expression values ENSG00000171246 ENSG00000125675 ENSG00000106236 ENSG00000221890 ENSG00000120251 PMC6114477__F1 Tumor-associated macrophages and epithelial-to-mesenchymal transition in hepatocellular carcinoma ENSG00000163464 ENSG00000169554 ENSG00000070831 ENSG00000138798 ENSG00000170558 ENSG00000168036 ENSG00000100985 ENSG00000168610 PMC4784721__F1 Major AGTR1 signalling pathways linked to cancer cell proliferation, angiogenesis and EMT ENSG00000146648 PMC6114477__F5 Virus-related products in the inflammatory tumor microenvironment ENSG00000100985 ENSG00000168610 PMC6114477__F4 Inflammatory mediators in hepatocellular carcinoma ENSG00000124102 ENSG00000169245 ENSG00000087245 ENSG00000156103 ENSG00000134013 ENSG00000163739 ENSG00000100985 PMC9214699__F5 Analysis of the expression, function and signaling of glycogen phosphorylase isoforms in hepatocellular carcinoma ENSG00000120833 ENSG00000044446 ENSG00000100994 ENSG00000050748 ENSG00000105647 ENSG00000143933 ENSG00000169032 ENSG00000076555 ENSG00000099942 ENSG00000132356 ENSG00000186298 ENSG00000111725 ENSG00000187840 ENSG00000109819 ENSG00000181929 ENSG00000106617 ENSG00000163558 ENSG00000067606 ENSG00000150907 ENSG00000171608 ENSG00000124253 ENSG00000125968 PMC6214858__F7 Schematic flow diagram of signal transmission from regulatory factors secreted by TM4 cells to ADSCs ENSG00000105329 ENSG00000138798 ENSG00000105656 PMC5508315__F2 Direct, indirect and semidirect pathway of allorecognition ENSG00000134982 ENSG00000026508 PMC6747268__F4 Signaling pathways involved in the switch between proliferation and dormancy ENSG00000135446 ENSG00000198793 PMC5508315__F1 Mechanism of regulatory T cell (Treg) suppression ENSG00000134982 PMC8569813__F2 Colon Cancer Progression Is Reflected to Monotonic Differentiation in Gene Expression and Pathway Deregulation Facilitating Stage–specific Drug Repurposing ENSG00000180210 ENSG00000109819 ENSG00000016490 ENSG00000184292 ENSG00000155850 PMC9379408__F10 Human CPTP promotes growth and metastasis via sphingolipid metabolite ceramide and PI4KA/AKT signaling in pancreatic cancer cells ENSG00000185591 PMC11793009__F9 Potential regulation loop of MET and ETS collaboration ENSG00000019991 ENSG00000109321 ENSG00000121966 PMC5506222__F4 Schematic model showing AA sensing signaling pathways that might modulate neuronal activity of central olfactory areas ENSG00000168003 ENSG00000124140 ENSG00000070985 ENSG00000036828 ENSG00000103257 PMC6289335__F1 Molecular actions of CTLA-4 and PD-1 on inhibiting T cell function ENSG00000198793 ENSG00000138777 PMC6877505__F1 Schematic view of microglial activation and cross-talks between microglia and other immune factors in the pathogenesis of Parkinson’s disease ENSG00000108691 ENSG00000125538 ENSG00000115009 PMC3191464__F2 Model depicting the pathway of TGFBeta-mediated Bim regulation and apoptosis ENSG00000159216 PMC8672524__F7 Transcriptomics of single dose and repeated carbon black and ozone inhalation co-exposure highlight progressive pulmonary mitochondrial dysfunction ENSG00000115163 ENSG00000122952 ENSG00000134057 ENSG00000184445 ENSG00000149503 PMC2727921__F1 Genetic polymorphisms, their allele combinations and IFNB treatment response in Irish multiple sclerosis patients ENSG00000159128 ENSG00000213928 ENSG00000117228 ENSG00000033800 ENSG00000027697 ENSG00000110324 ENSG00000164305 ENSG00000142166 ENSG00000162594 ENSG00000096996 ENSG00000138035 ENSG00000105397 ENSG00000115415 ENSG00000243646 ENSG00000105246 PMC6420874__F1 Mechanisms by which radiation enhances immunotherapy ENSG00000164430 ENSG00000198053 ENSG00000189403 PMC3122316__F1 F igure 1.— PMC8495383__F3 Enolase 1, a Moonlighting Protein, as a Potential Target for Cancer Treatment ENSG00000074800 ENSG00000136869 ENSG00000166484 ENSG00000081189 ENSG00000162896 PMC4223001__F1 Harnessing Hippo in the heart: Hippo/YAP1 signaling and applications to heart regeneration and rejuvenation ENSG00000126016 ENSG00000186575 ENSG00000291971 ENSG00000163914 ENSG00000168036 ENSG00000198670 PMC7312732__F6 Activation of the TRPV1 ligand-gated ion channel and subsequent [Ca2+]i and protein signaling influence the balance between proliferation and apoptosis ENSG00000149311 ENSG00000128272 ENSG00000132478 ENSG00000100219 ENSG00000146648 ENSG00000196689 PMC6769685__F5 Apoptotic pathways triggered by inosine 5′-monophosphate dehydrogenase (IMPDH) inhibitors ENSG00000291971 ENSG00000198793 PMC7407888__F1 Scheme illustrating the IL-10 signaling pathway ENSG00000105397 ENSG00000168610 PMC9478028__F3 Hepatitis B virus DNA integration as a novel biomarker of hepatitis B virus-mediated pathogenetic properties and a barrier to the current strategies for hepatitis B virus cure ENSG00000164362 ENSG00000168036 ENSG00000135476 ENSG00000145386 PMC3396155__F5 The balance in signalling through either ALK-1 or ALK-5 regulates leptin expression in MSC ENSG00000170365 PMC7312732__F2 TRPV1 induces proliferation through Ca2+ entry, ATP release and membrane P2Y2 receptor activation, and the transactivation of epidermal growth factor receptor (EGFR) ENSG00000291971 ENSG00000005882 ENSG00000146648 ENSG00000196689 PMC8583859__F2 Mechanistic Insight from Preclinical Models of Parkinson’s Disease Could Help Redirect Clinical Trial Efforts in GDNF Therapy ENSG00000162711 ENSG00000135218 ENSG00000125538 ENSG00000136869 PMC8531643__F1 Aberrant Metabolism as Inductor of Epigenetic Changes in Breast Cancer: Therapeutic Opportunities ENSG00000101945 ENSG00000198793 ENSG00000169710 ENSG00000081692 PMC7518150__F5 Molecular mechanism of Wnt/Beta-catenin signaling pathway activation ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3918842__F2 Pathways for the synthesis of phospholipids and their interconnection ENSG00000185813 ENSG00000173599 ENSG00000133027 PMC5828202__F10 Silibinin sensitizes TRAIL-mediated apoptosis by upregulating DR5 through ROS-induced endoplasmic reticulum stress-Ca2+-CaMKII-Sp1 pathway ENSG00000128272 ENSG00000144895 ENSG00000185591 PMC5468621__F5 Summary of signaling events and downstream transcription factors driving specification of the blood stem cell lineage ENSG00000105672 ENSG00000148400 ENSG00000152804 ENSG00000179348 PMC8964100__F8 Dihydromyricetin Alleviates Pulmonary Fibrosis by Regulating Abnormal Fibroblasts Through the STAT3/p-STAT3/GLUT1 Signaling Pathway ENSG00000197299 ENSG00000108821 ENSG00000168610 PMC6093060__F7 NFKB inflammatory signaling pathway ENSG00000172936 ENSG00000136869 PMC8876671__F3 SALL4 Oncogenic Function in Cancers: Mechanisms and Therapeutic Relevance ENSG00000135547 ENSG00000283780 ENSG00000074181 ENSG00000101115 ENSG00000114315 ENSG00000143995 PMC5481366__F1 Estrogen biosynthesis ENSG00000086696 ENSG00000149084 ENSG00000132196 ENSG00000108786 PMC3875949__F1 Regulation of metabolism in maligant gliomas ENSG00000131473 ENSG00000146648 ENSG00000115419 ENSG00000159399 ENSG00000026103 PMC5811730__F4 Distinct mechanisms of small-molecule inhibitors and monoclonal antibodies for targeting receptor tyrosine kinases in cancer cells ENSG00000138798 ENSG00000203710 ENSG00000146648 ENSG00000117322 PMC8666372__F3 Activated and inactivated canonical Wnt signaling ENSG00000156076 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000120057 PMC5811730__F3 Rationale for targeting both the Ras/Raf/MEK/ERK and Ras/PI3K/PTEN/Akt/mTOR pathways for suppressing cancer growth ENSG00000169291 ENSG00000002330 ENSG00000108557 ENSG00000198793 ENSG00000146648 PMC8666372__F1 Activated and inactivated canonical Wnt signaling ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC8876671__F2 SALL4 Oncogenic Function in Cancers: Mechanisms and Therapeutic Relevance ENSG00000168283 ENSG00000101115 PMC8876671__F1 SALL4 Oncogenic Function in Cancers: Mechanisms and Therapeutic Relevance ENSG00000154342 ENSG00000168283 ENSG00000101255 ENSG00000101115 ENSG00000168036 ENSG00000168646 ENSG00000196628 PMC8231959__F1 Coenzyme Q Biosynthesis: An Update on the Origins of the Benzenoid Ring and Discovery of New Ring Precursors ENSG00000132423 ENSG00000267673 ENSG00000119723 ENSG00000110871 ENSG00000163914 ENSG00000161513 ENSG00000197429 ENSG00000137714 ENSG00000173085 ENSG00000167186 PMC3342071__F2 FcERI signaling events in WT, NTAL−/−, and LAT−/− cells ENSG00000033327 ENSG00000213658 PMC8920690__F1 Nervous System Contributes to the Tumorigenesis and Progression of Human Digestive Tract Cancer ENSG00000291971 ENSG00000140443 PMC5905346__F1 GCs stimulate GSK3ß and inhibit Wnt signaling ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC7927137__F5 Circadian clock machinery regulates the biosynthesis of NAD+ through control of the NAD+ salvage pathway ENSG00000105835 ENSG00000096717 PMC2744278__F3 Phosphatidylinositol 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) signaling pathways ENSG00000002330 ENSG00000198793 PMC6041767__F2 Example module (L1) more densely connected in ER- group with red nodes indicate genes belonging to the immune response pathway ENSG00000145147 ENSG00000140092 ENSG00000143226 ENSG00000104332 ENSG00000141968 ENSG00000182326 ENSG00000266964 ENSG00000184500 ENSG00000155307 ENSG00000166292 ENSG00000112182 ENSG00000275565 ENSG00000086730 ENSG00000283934 ENSG00000137033 ENSG00000101265 ENSG00000198851 ENSG00000000971 ENSG00000205220 ENSG00000078596 ENSG00000128284 ENSG00000164056 ENSG00000132514 ENSG00000112149 ENSG00000143196 ENSG00000164949 PMC2830970__F1 Schematics of the retroviral replication cycle ENSG00000121966 PMC6084457__F1 Metabolic pathways contributing to HSC self-renewal and differentiation ENSG00000157184 ENSG00000205221 ENSG00000060982 ENSG00000136997 ENSG00000110536 PMC10138908__F7 Which OBHS remodels abnormal glycometabolism, referring the experiment results ENSG00000074800 PMC6782151__F11 Mechanism of microglial activation by fibrillarBA and PrP peptides responsible for neurotoxicity PMC1134761__F4 Essential tension and constructive destruction: the spindle checkpoint and its regulatory links with mitotic exit ENSG00000134982 ENSG00000167434 PMC7281073__F1 PI3K/AKT/mTOR pathway activation leads to cell growth, increased protein synthesis, inhibited apoptosis, cell cycle progression and proliferation ENSG00000002330 ENSG00000144554 ENSG00000146648 PMC3625357__F11 IPA-generated gene network linking 88 of 445 genes shown by microarray analysis to be significantly (P < 0.01) up- (blue) or down- (red) regulated >twofold in bovine TCs in response to BMP6 treatment ENSG00000169908 ENSG00000111057 ENSG00000112972 ENSG00000111859 ENSG00000109906 ENSG00000170558 ENSG00000117298 ENSG00000149294 ENSG00000169710 ENSG00000140092 ENSG00000112715 ENSG00000163815 ENSG00000064300 ENSG00000119681 ENSG00000136826 ENSG00000104368 ENSG00000196136 ENSG00000123999 ENSG00000011422 ENSG00000038427 ENSG00000116133 ENSG00000129214 ENSG00000011028 ENSG00000125538 ENSG00000133134 ENSG00000283060 ENSG00000125968 ENSG00000135919 ENSG00000158859 ENSG00000138039 ENSG00000197632 ENSG00000008394 ENSG00000248099 ENSG00000164120 ENSG00000073756 ENSG00000184481 ENSG00000203857 ENSG00000007171 ENSG00000066468 ENSG00000167772 ENSG00000242247 ENSG00000118495 ENSG00000172602 ENSG00000019549 ENSG00000151617 ENSG00000114315 ENSG00000115009 PMC10383966__F4 Pellino Proteins in Viral Immunity and Pathogenesis ENSG00000172936 ENSG00000276561 ENSG00000184216 PMC5445144__F4 Regulatory T cell (Treg) action mechanisms ENSG00000089692 ENSG00000163599 PMC10383966__F1 Pellino Proteins in Viral Immunity and Pathogenesis ENSG00000278718 ENSG00000183735 ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC7473936__F12 Vascular permeability disruption explored in the proteomes of mouse lungs and human microvascular cells following acute bromine exposure ENSG00000106683 ENSG00000104140 ENSG00000070831 ENSG00000143878 ENSG00000169750 ENSG00000149269 ENSG00000163914 PMC7246454__F1 DNA Damage Response and HIV-Associated Pulmonary Arterial Hypertension ENSG00000149311 ENSG00000012048 ENSG00000175054 PMC3248879__F1 Network images of FTO and candidates genes ENSG00000070087 ENSG00000138078 ENSG00000145687 ENSG00000036672 ENSG00000105568 ENSG00000109738 ENSG00000115464 ENSG00000148660 ENSG00000123213 ENSG00000117758 ENSG00000220205 ENSG00000183741 ENSG00000145029 ENSG00000140743 PMC9680067__F4 Teleost NOD-like receptors and their downstream signaling pathways: A brief review ENSG00000162711 ENSG00000198793 ENSG00000112715 ENSG00000175104 ENSG00000168610 PMC3248879__F4 In silico analysis and gene expression studies suggests functional coupling between FTO and the BDNF/NTRK2-signalling pathway ENSG00000172216 ENSG00000122877 PMC9680067__F6 Teleost NOD-like receptors and their downstream signaling pathways: A brief review ENSG00000162711 ENSG00000150782 ENSG00000226275 ENSG00000125538 ENSG00000174885 ENSG00000091592 ENSG00000142405 PMC9680067__F3 Teleost NOD-like receptors and their downstream signaling pathways: A brief review ENSG00000088888 ENSG00000167207 ENSG00000106100 ENSG00000276561 PMC8339999__F9 Kaempferol Alleviates Murine Experimental Colitis by Restoring Gut Microbiota and Inhibiting the LPS-TLR4-NFKB Axis ENSG00000162711 ENSG00000172936 PMC4468292__F1 Influence of the inflammatory cytokines on the status of insulin resistance ENSG00000169047 ENSG00000136869 ENSG00000168610 PMC5704542__F8 Model for regulation of nitrogen availability response PMC9483726__F3 Comprehensive elaboration of circular RNA in multiple myeloma ENSG00000145604 ENSG00000141867 ENSG00000117020 ENSG00000126775 ENSG00000141639 ENSG00000105810 ENSG00000118777 PMC2824707__F1 Tissue level and signalling pathways for PGE2 is presented ENSG00000168036 ENSG00000146648 PMC5207147__F13 Proposed model on the cross-talk between HGF/c-Met and SphK1/S1P/Spns2/S1P1signaling axis in HGF-mediated lamellipodia formation ENSG00000019991 ENSG00000183018 PMC4373397__F2 Mucosal barrier integrity and inflammation ENSG00000108691 ENSG00000096395 ENSG00000137033 ENSG00000125538 ENSG00000145777 ENSG00000166090 PMC4440219__F7 MiR-503 mediates constitutive suppression of the IGF-1R pathway leading to a less aggressive glioma phenotype ENSG00000002330 ENSG00000140443 PMC8256367__F3 How Transmembrane Inner Ear (TMIE) plays role in the auditory system: A mystery to us ENSG00000181585 ENSG00000149488 ENSG00000165091 PMC8608616__F4 Redox regulation of DUBs and its therapeutic implications in cancer ENSG00000081913 ENSG00000102226 ENSG00000163235 ENSG00000125538 ENSG00000172046 ENSG00000162607 ENSG00000048028 ENSG00000083799 ENSG00000168610 PMC3460412__F1 Activation of p38 MAPK downstrem of TNFR1 ENSG00000102871 ENSG00000082512 ENSG00000127191 PMC1867237__F3 ErbB/Ras pathway and Wnt pathway ENSG00000107404 ENSG00000134982 ENSG00000136997 ENSG00000169884 ENSG00000168036 PMC4872445__F2 Distinct roles of enzymes MTHFD1L and MTHFR in the folate-related one-carbon cycle ENSG00000100714 ENSG00000120254 PMC6028513__F2 TRIMming TGFB signals in Th17 cells ENSG00000049768 PMC5488350__F1 The Taste of Caffeine ENSG00000185933 ENSG00000070985 ENSG00000137841 PMC2886325__F3 PI3K-Akt-mTOR pathway and cross-talk with other signaling cascades: (Ras/Raf/MAPK and BCR-ABL) ENSG00000138798 ENSG00000198793 PMC3319521__F1 The CD47-SIRPA Pathway in Cancer Immune Evasion and Potential Therapeutic Implications ENSG00000198053 PMC4971811__F7 Proposed model for increased IL-6 and leptin production caused by global Zip14 deletion ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000168610 PMC8396208__F3 GDF15 and Cardiac Cells: Current Concepts and New Insights ENSG00000178860 ENSG00000130513 PMC8396208__F2 GDF15 and Cardiac Cells: Current Concepts and New Insights ENSG00000178860 ENSG00000187871 ENSG00000105550 ENSG00000130513 PMC4940573__F1 Strategies for modulating the BMP pathway ENSG00000170365 ENSG00000198742 PMC3875463__F1 MTOR pathway and epilepsy ENSG00000117020 ENSG00000121879 PMC7751413__F1 P53 signaling pathway of the large yellow croaker (Larimichthys crocea) responds to acute cold stress: evidence via spatiotemporal expression analysis of p53, p21, MDM2, IGF-1, Gadd45, Fas, and Akt ENSG00000135446 ENSG00000198793 ENSG00000196470 ENSG00000105810 ENSG00000064012 ENSG00000026103 PMC5217378__F6 Ingenuity Pathway Analysis showing the top molecular network in HSPC-derived myeloid cells collected at 6 months after exposure of mice to 0.25 Gy of 48Ti ions ENSG00000159166 ENSG00000170075 ENSG00000018510 ENSG00000291431 ENSG00000243056 ENSG00000170454 ENSG00000102710 ENSG00000169752 ENSG00000154451 ENSG00000182585 ENSG00000139687 ENSG00000164086 ENSG00000292033 PMC9136582__F1 Development of small molecule extracellular signal-regulated kinases (ERKs) inhibitors for cancer therapy ENSG00000149930 ENSG00000160551 ENSG00000163914 ENSG00000081189 PMC4295939__F8 Inactivation of PNKP by Mutant ATXN3 Triggers Apoptosis by Activating the DNA Damage-Response Pathway in SCA3 ENSG00000149311 ENSG00000039650 ENSG00000173599 PMC5217378__F7 Ingenuity Pathway Analysis showing the top molecular network in HSPC-derived myeloid cells collected at 6 months after exposure of mice to 0.5 Gy of 48Ti ions ENSG00000172809 ENSG00000101361 ENSG00000136942 PMC2665873__F1 Fatty acid synthesis pathways in C ENSG00000083857 ENSG00000165323 ENSG00000026103 PMC5217378__F2 Ingenuity Pathway Analysis showing the top molecular Network in HSPC-derived myeloid cells collected at 1 week after exposure of mice to 0.1 Gy of 48Ti ions ENSG00000215421 ENSG00000134970 ENSG00000278718 ENSG00000169976 ENSG00000172869 ENSG00000137133 ENSG00000125912 ENSG00000183011 ENSG00000159322 ENSG00000125827 ENSG00000274779 ENSG00000115806 ENSG00000095380 ENSG00000133313 ENSG00000150991 ENSG00000048707 ENSG00000151366 ENSG00000146386 ENSG00000035141 ENSG00000130309 ENSG00000126464 PMC6747541__F3 Syntenin-mediated signaling in the regulation of membrane structure and cell motility ENSG00000087245 ENSG00000070831 ENSG00000291971 ENSG00000135404 PMC6890838__F3 Mutant proteasomes from CANDLE/PRAAS subjects have a potential pro-inflammatory potential due to the negative impact they exert on mTORC1 ENSG00000183735 ENSG00000128272 ENSG00000144895 ENSG00000155792 ENSG00000285069 PMC6890838__F2 Defective proteasomes in CANDLE/PRAAS subjects provoke ER stress and trigger the so-called unfolded protein response (UPR) which is associated with inflammation ENSG00000183735 ENSG00000088888 ENSG00000128272 ENSG00000144895 PMC9618966__F6 Macrophage scavenger receptor 1 (MSR1) in inflammatory disorders and cancer ENSG00000226275 ENSG00000177606 ENSG00000136997 ENSG00000172936 ENSG00000164342 PMC3095999__F2 Literature-based connections among genes in altered modules of head and neck squamous cell carcinoma (HNSCC) ENSG00000196136 ENSG00000133110 ENSG00000109321 ENSG00000125538 ENSG00000136997 ENSG00000100985 ENSG00000146648 ENSG00000115009 PMC7321691__F1 RT activates the IFNs-JAK/STAT1 pathway in cancer cells ENSG00000213928 ENSG00000108515 ENSG00000089127 ENSG00000183486 ENSG00000157601 ENSG00000163064 ENSG00000185745 ENSG00000185885 ENSG00000125347 ENSG00000184979 ENSG00000169245 ENSG00000152778 ENSG00000275214 ENSG00000074800 ENSG00000111537 ENSG00000188313 ENSG00000105397 ENSG00000115415 ENSG00000138755 ENSG00000137965 ENSG00000177606 ENSG00000164778 PMC8268006__F1 Beyond RAS and BRAF: HER2, a New Actionable Oncotarget in Advanced Colorectal Cancer ENSG00000157764 ENSG00000198793 ENSG00000121879 ENSG00000168610 ENSG00000146648 PMC5078854__F1 Metabolic pathway of citrate and isocitrate on the citric acid cycle in the mitochondrial matrix and in the cytosol ENSG00000100412 PMC6363433__F2 Folate decomposition and damage repair ENSG00000284320 ENSG00000228716 ENSG00000136371 PMC11074409__F2 Activity of probiotics, synbiotics and postbiotics ENSG00000111537 ENSG00000168036 ENSG00000113520 ENSG00000171791 PMC2577687__F1 Metabolic scheme ENSG00000122966 ENSG00000173599 ENSG00000172005 PMC11731763__F9 Signaling pathway of LH resist apoptosis and promote proliferation of freeze-thaw folliculars and granulosa cells by TGFB and its superfamily members ENSG00000164404 ENSG00000130385 PMC3375400__F1 Comparison of the pathways responsible for the anti-apoptotic and pro-apoptotic effects of immune complexes containing oxidized LDL (oxLDL-IC) and malondialdehyde-modified LDL (MDA-LDL-IC) ENSG00000135218 ENSG00000002330 PMC7555004__F3 Some proposed mechanisms of aging involving xanthine oxidoreductase (XOR) and its products ENSG00000149311 ENSG00000162711 ENSG00000125538 ENSG00000198793 ENSG00000096717 PMC8533761__F1 Impairments in Brain Bioenergetics in Aging and Tau Pathology: A Chicken and Egg Situation? ENSG00000180210 PMC11970819__F1 Pathophysiology and emerging therapeutic targets of IBD ENSG00000162594 ENSG00000134982 ENSG00000020633 ENSG00000103522 PMC2613125__F6 Interleukin-6 and Neural Stem Cells: More Than Gliogenesis ENSG00000242689 ENSG00000138798 PMC8059031__F3 ncRNA regulatory network map of acute myocardial infarction ENSG00000253352 PMC2528847__F2 Integration of genomic and nongenomic/rapid ER signaling and its crosstalk with growth factor receptor and cell kinase pathways in endocrine resistance: a working model ENSG00000113070 ENSG00000146648 PMC4157971__F7 Ligation of ICAM-1 on human aortic valve interstitial cells induces the osteogenic response: a critical role of the Notch1–NFKB pathway in BMP-2 expression ENSG00000148400 ENSG00000136869 PMC7191956__F5 Tomatidine-targeted genes-related part of the top five shared KEGG pathways ENSG00000177189 ENSG00000281877 ENSG00000169032 ENSG00000152430 PMC7388413__F1 The PI3K pathway in cancer cells ENSG00000124102 ENSG00000198793 ENSG00000146648 PMC7312293__F2 Key negative and positive regulators for NLRP3 inflammasome ENSG00000162711 ENSG00000173599 ENSG00000086991 ENSG00000175567 ENSG00000183484 PMC9248759__F6 Is Estrogen a Missing Culprit in Thyroid Eye Disease? Sex Steroid Hormone Homeostasis Is Key to Other Fibrogenic Autoimmune Diseases – Why Not This One? ENSG00000140443 PMC8787213__F2 Research Advances in Multi-Omics on the Traditional Chinese Herb Dendrobium officinale ENSG00000109814 ENSG00000111816 ENSG00000047597 PMC4415653__F6 Genetic regulatory network based on published interactions ENSG00000128272 ENSG00000173039 ENSG00000185591 PMC8787213__F1 Research Advances in Multi-Omics on the Traditional Chinese Herb Dendrobium officinale ENSG00000110921 ENSG00000197429 ENSG00000174607 PMC5715731__F9 Model illustrating the intracellular signaling pathway leading to cell proliferation and survival in response to NRG-1B treatment ENSG00000065361 PMC8115506__F1 Excess levels of cytoplasmic TDP-43 lead to mitochondrial penetration of TDP-43 which may trigger mtDNA release with ensuing activation of the cGAS/STING immune sensor ENSG00000180210 ENSG00000183735 ENSG00000164430 PMC7768821__F9 Possible mechanism(s) of suppression of alcoholic hepatosteatosis by physcion ENSG00000162711 ENSG00000125538 PMC4415653__F3 SP1, JUN and STAT1 subnetwork from the Brown module ENSG00000196531 ENSG00000143549 ENSG00000128272 ENSG00000115415 ENSG00000177606 ENSG00000198554 ENSG00000185591 PMC6517835__F9 Foxi3 inhibits epithelial differentiation and promotes suprabasal cell formation ENSG00000120057 ENSG00000214336 PMC7054714__F5 Immune Responses to Viral Gene Therapy Vectors ENSG00000164430 ENSG00000125538 ENSG00000198793 PMC8801025__F3 Organoids to model the endometrium: implantation and beyond ENSG00000154342 ENSG00000070193 ENSG00000138798 PMC7054714__F3 Immune Responses to Viral Gene Therapy Vectors ENSG00000239732 ENSG00000111537 ENSG00000125538 ENSG00000172936 ENSG00000142166 PMC6633015__F8 The signaling pathway mediated by GABAB receptor in CGN neuroprotection ENSG00000124102 ENSG00000291971 ENSG00000140443 PMC6123661__F8 Planar cell polarity gene Fuz triggers apoptosis in neurodegenerative disease models ENSG00000156299 ENSG00000010361 PMC3138369__F1 Signaling pathway for epidermal growth factor receptor (EGFR) ENSG00000151657 ENSG00000198793 ENSG00000146648 PMC4322317__F6 Protein Complex Discovery by Interaction Filtering from Protein Interaction Networks Using Mutual Rank Coexpression and Sequence Similarity ENSG00000171311 ENSG00000107371 ENSG00000030066 ENSG00000083520 ENSG00000292130 ENSG00000291737 ENSG00000077348 ENSG00000176095 ENSG00000178896 PMC8615581__F2 Ferroptosis in Non-Alcoholic Fatty Liver Disease and Its Implications for Therapeutic Strategies ENSG00000167468 ENSG00000197429 ENSG00000111684 ENSG00000079999 PMC9375325__F2 PI3K/AKT pathway in squamous cell carcinoma with an especial focus on head and neck cancers ENSG00000140992 ENSG00000002330 ENSG00000058085 ENSG00000170558 ENSG00000150907 ENSG00000143590 ENSG00000119681 ENSG00000109670 PMC6887790__F4 Biochemical pathway in neutrophils showing the signaling cascade and the effects related to DAG and PA activation ENSG00000163464 ENSG00000169429 PMC9375325__F1 PI3K/AKT pathway in squamous cell carcinoma with an especial focus on head and neck cancers ENSG00000087245 ENSG00000170558 ENSG00000198793 ENSG00000155792 ENSG00000167965 PMC4151153__F2 Toll-like receptor 4 (TLR4) signaling pathway by Lactobacillus casei OLL2768, Bifidobacterium adolescentis MCC-75, and Bifidobacterium adolescentis ATCC15705 in bovine intestinal epithelial epitheliocytes (BIE cells) ENSG00000170458 ENSG00000177606 ENSG00000134070 ENSG00000113520 ENSG00000136869 ENSG00000185187 PMC7297493__F1 Schematic representation of the hypothesized downstream pathways to ASCL1 and MYT1L during transdifferentiation ENSG00000186487 ENSG00000272333 ENSG00000139352 PMC2691592__F7 Caenorhabditis elegans Protein Arginine Methyltransferase PRMT-5 Negatively Regulates DNA Damage-Induced Apoptosis PMC9167730__F3 TLR-dependent signaling pathways are modulated by allosteric activation of CD11b ENSG00000291971 ENSG00000172936 PMC9322956__F1 Computational Methods in Cooperation with Experimental Approaches to Design Protein Tyrosine Phosphatase 1B Inhibitors in Type 2 Diabetes Drug Design: A Review of the Achievements of This Century ENSG00000065361 ENSG00000291971 ENSG00000169047 ENSG00000168610 PMC3156870__F1 Resistance to RAF inhibitors in melanoma ENSG00000117020 ENSG00000157764 ENSG00000104081 ENSG00000140443 PMC7415163__F1 Complement activation pathways and narsoplimab mechanism of action ENSG00000288512 ENSG00000166278 ENSG00000182326 PMC11790847__F1 Multiple post-transcriptional modifications regulate cancer progression via manipulating the activity of the Hippo signalling pathway ENSG00000152484 ENSG00000198492 ENSG00000150457 ENSG00000131023 ENSG00000165819 PMC10312162__F4 Changes in the metabolic pathways of young and old leaves in the two soybean ecotypes ENSG00000180210 ENSG00000144063 PMC3534236__F3 Autophagy and selective deployment of Atg proteins in antiviral defense ENSG00000174125 ENSG00000239732 ENSG00000057663 ENSG00000164342 PMC11853365__F1 Multifaceted roles of ApoE4-induced Glial dysfunction in Alzheimer’s disease pathology ENSG00000162711 PMC7244030__F8 LOC646616/miR-637/WNT3 ceRNA network in EH ENSG00000168036 ENSG00000163888 ENSG00000277641 PMC7243138__F2 Pin1-mediated APP processing ENSG00000127445 ENSG00000142192 PMC6755804__F4 Selection of enriched pathways and genes and their involvement in various tumorigenic pathways ENSG00000124092 ENSG00000169925 ENSG00000125740 ENSG00000092758 ENSG00000058085 ENSG00000162496 ENSG00000181274 ENSG00000163739 ENSG00000198793 ENSG00000197746 ENSG00000095951 ENSG00000140961 ENSG00000064300 ENSG00000136002 ENSG00000157557 ENSG00000156299 ENSG00000119397 ENSG00000163914 ENSG00000183579 ENSG00000187908 ENSG00000177519 ENSG00000120008 ENSG00000145824 ENSG00000164128 ENSG00000182568 ENSG00000101265 ENSG00000153201 ENSG00000100815 ENSG00000163530 ENSG00000184481 ENSG00000106003 ENSG00000132170 ENSG00000166033 ENSG00000068028 ENSG00000019582 ENSG00000101972 ENSG00000189334 ENSG00000100387 ENSG00000161513 ENSG00000165288 ENSG00000198728 ENSG00000164362 ENSG00000107485 ENSG00000126947 ENSG00000128602 ENSG00000146648 PMC12071403__F6 Correlation between stress-mediated inflammation and major depression ENSG00000168209 ENSG00000155926 ENSG00000019186 ENSG00000198793 ENSG00000197728 ENSG00000164399 ENSG00000196350 ENSG00000283060 ENSG00000132356 ENSG00000148730 ENSG00000174607 PMC6349770__F2 Implementation of metabolic engineering strategies in S ENSG00000158125 PMC9363121__F7 Possible model of Banp functions in stalled fork recovery, DNA damage repair, and chromosome segregation during mitosis ENSG00000149311 ENSG00000124535 ENSG00000175054 ENSG00000109805 ENSG00000172530 PMC12071403__F4 Inflammatory Factors: A Key Contributor to Stress-Induced Major Depressive Disorder ENSG00000104856 ENSG00000082512 ENSG00000056558 ENSG00000131323 ENSG00000124181 ENSG00000175104 ENSG00000127191 ENSG00000076604 PMC5550428__F6 Regulation of ΔF508 CFTR stability by inhibitors to the PI3K/Akt/mTOR pathway ENSG00000284774 ENSG00000151929 ENSG00000001626 PMC6755804__F5 Network of pathways and genes induced by P152Lp53 expression ENSG00000171777 ENSG00000181274 ENSG00000198793 ENSG00000163914 ENSG00000197746 ENSG00000131477 ENSG00000146648 ENSG00000173230 PMC7467273__F2 Genome-wide analysis of DNA methylation in testis of male rat exposed to chlorpyrifos ENSG00000142192 ENSG00000113456 ENSG00000291603 ENSG00000002330 ENSG00000213658 ENSG00000111837 ENSG00000163914 ENSG00000178209 ENSG00000198125 ENSG00000127948 PMC6292568__F2 Candida–streptococcal interactions in biofilm-associated oral diseases PMC11581872__F8 Huyang Yangkun formula regulates the mitochondria pathway of ovarian granulosa cell apoptosis through FTO/m6A-P53 pathway ENSG00000145388 ENSG00000171791 ENSG00000164305 ENSG00000165819 PMC11676253__F1 Anti-Müllerian Hormone (AMH), signaling pathway in granulosa cells ENSG00000104899 ENSG00000135409 PMC8654699__F6 Targeting SOS1 overcomes imatinib resistance with BCR-ABL independence through uptake transporter SLC22A4 in CML ENSG00000115904 ENSG00000197208 PMC7237910__F3 Spiking Pandemic Potential: Structural and Immunological Aspects of SARS-CoV-2 ENSG00000130234 ENSG00000184012 PMC6671871__F1 Lignin biosynthetic pathway ENSG00000165757 ENSG00000084774 PMC4550414__F5 Network Topologies Decoding Cervical Cancer ENSG00000135446 ENSG00000198793 ENSG00000112715 PMC5923480__F2 Feline restriction factors and FIV counteraction mechanisms ENSG00000132824 ENSG00000121966 PMC8348676__F2 Mechanism and Effect of Autophagy, Apoptosis, and Pyroptosis on the Progression of Silicosis ENSG00000144895 ENSG00000026103 PMC8348676__F1 Mechanism and Effect of Autophagy, Apoptosis, and Pyroptosis on the Progression of Silicosis ENSG00000130749 ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000184743 PMC2173691__F7 Mechanisms of E-cadherin regulation in sparse and dense cultures of colon cancer cells ENSG00000168036 ENSG00000084774 PMC7338763__F1 What Matters for C4 Transporters: Evolutionary Changes of Phosphoenolpyruvate Transporter for C4 Photosynthesis ENSG00000172005 ENSG00000145321 ENSG00000062485 PMC8784274__F3 Transcriptomic Analysis Reveals a Link Between Hippo Signaling Pathway and Macrophages in Lungs of Mice with OVA-Induced Allergic Asthma ENSG00000112576 ENSG00000154764 ENSG00000105327 ENSG00000134982 ENSG00000169884 ENSG00000157240 ENSG00000148498 ENSG00000213658 ENSG00000163251 ENSG00000089685 ENSG00000163558 ENSG00000136997 ENSG00000111186 ENSG00000134245 ENSG00000177283 ENSG00000125968 ENSG00000134376 ENSG00000162552 ENSG00000129474 ENSG00000113645 ENSG00000154342 ENSG00000126016 ENSG00000138795 ENSG00000109321 ENSG00000174804 ENSG00000197905 ENSG00000139926 ENSG00000018408 ENSG00000276920 ENSG00000150457 ENSG00000074219 ENSG00000140807 ENSG00000068028 ENSG00000074211 ENSG00000148204 ENSG00000115266 ENSG00000019549 ENSG00000168646 ENSG00000124171 ENSG00000204217 ENSG00000178184 PMC7005212__F4 Compound-potential targets-disease network (Blue diamond represents compound target; red circle represents pathway; purple hexagon represents disease) ENSG00000173039 ENSG00000073756 ENSG00000102977 PMC8278527__F7 SFRP5 inhibits melanin synthesis of melanocytes in vitiligo by suppressing the Wnt/Beta-catenin signaling ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000120057 ENSG00000168036 PMC5388917__F5 Regulation of Akt signaling pathways after (A) vehicle, and (B) melatonin treatments following ischemic-stroke ENSG00000002330 ENSG00000198793 ENSG00000105723 PMC9218606__F4 Epigenetic Therapeutics Targeting NRF2/KEAP1 Signaling in Cancer Oxidative Stress ENSG00000181019 ENSG00000079999 PMC9506554__F1 Genetic Variants in One-Carbon Metabolism and Their Effects on DHA Biomarkers in Pregnant Women: A Post-Hoc Analysis ENSG00000284320 ENSG00000100714 ENSG00000133027 PMC3497272__F2 ErbB signaling and inhibition in tumour cell ENSG00000033327 ENSG00000002330 ENSG00000065361 ENSG00000171791 ENSG00000168610 PMC5769965__F10 Cocaine and HIV-1 Tat Disrupt Cholesterol Homeostasis in Astrocytes: Implications for HIV-Associated Neurocognitive Disorders in Cocaine User Patients ENSG00000130164 PMC2732569__F2 The role of PTEN-induced kinase 1 in mitochondrial dysfunction and dynamics ENSG00000158828 ENSG00000079557 ENSG00000214253 PMC2097959__F2 INTEGRATING RADIOTHERAPY WITH EGFR ANTAGONISTS AND OTHER MOLECULAR THERAPEUTICS FOR THE TREATMENT OF HEAD AND NECK CANCER ENSG00000198793 ENSG00000146648 PMC5143322__F1 AHR signaling pathway ENSG00000177606 ENSG00000173039 ENSG00000106546 PMC5768915__F1 HN1L Promotes Triple-Negative Breast Cancer Stem Cells through LEPR-STAT3 Pathway ENSG00000066468 ENSG00000125398 ENSG00000168610 PMC4113076__F7 Comprehensive and High Resolution Genome-wide Response of p53 to Stress ENSG00000147162 ENSG00000132467 ENSG00000285069 ENSG00000076604 ENSG00000126012 ENSG00000172167 ENSG00000048392 ENSG00000257218 ENSG00000134574 ENSG00000132646 ENSG00000108384 ENSG00000117528 ENSG00000173846 ENSG00000078808 PMC3932967__F2 Role of Notch signaling in the mammalian heart ENSG00000087245 ENSG00000121068 ENSG00000163217 PMC4095017__F2 Signaling and cross talk of the parathyroid hormone and Wnt signaling pathways in the late osteoblast (osteocyte) ENSG00000180210 ENSG00000152266 ENSG00000154342 ENSG00000281324 ENSG00000162337 ENSG00000168646 PMC11663867__F4 Cerebrotendinous xanthomatosis: a literature review and case study ENSG00000167910 ENSG00000099377 ENSG00000135929 PMC9142813__F1 Cellular and molecular basis of thyroid autoimmunity ENSG00000042832 ENSG00000165409 PMC4204733__F3 Schematic diagrams of Wingless and Arm structure, and pathway relationships ENSG00000134982 ENSG00000167074 PMC8691188__F1 Mathematical Model to Characterize the Role of Light Adaptation in Mammalian Circadian Clock ENSG00000142178 ENSG00000132326 ENSG00000179094 PMC4518444__F6 Checkpoint clamp and clamp loader in crossover formation ENSG00000175054 ENSG00000051180 ENSG00000100206 PMC3666388__F5 Adult haemangioblast genetic regulatory network ENSG00000151702 ENSG00000105672 ENSG00000111145 ENSG00000172889 ENSG00000285438 ENSG00000037280 ENSG00000112715 ENSG00000179348 PMC3515549__F7 Screening the Budding Yeast Genome Reveals Unique Factors Affecting K2 Toxin Susceptibility ENSG00000159063 ENSG00000006715 PMC3250521__F4 Inhibition of isoprenoid biosynthetic pathway by ATST [modified from Holstein et al ENSG00000143878 ENSG00000197429 PMC4007119__F6 ZZ primary bronchial epithelial cells show an enhanced inflammatory response dependent of the ERK/EGFR/ADAM17 pathway ENSG00000109321 ENSG00000163235 ENSG00000146648 PMC7952751__F4 Interplay between autophagy and apoptosis, and the regulation of autophagy and apoptosis by foot-and-mouth disease virus (FMDV) infection ENSG00000128272 ENSG00000126775 ENSG00000144895 ENSG00000102871 PMC9505762__F1 Impact of Environmental Risk Factors on Mitochondrial Dysfunction, Neuroinflammation, Protein Misfolding, and Oxidative Stress in the Etiopathogenesis of Parkinson’s Disease ENSG00000162711 ENSG00000125538 ENSG00000171791 PMC7952751__F3 Schematic representation showing the interaction between foot-and-mouth disease virus (FMDV) viral proteins and host proteins in the innate immune system ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000089127 ENSG00000008952 ENSG00000157601 ENSG00000131323 ENSG00000168610 ENSG00000276561 PMC7974548__F3 Mechanisms of cardiotoxicityAbnormalities in action potential duration or conduction velocity are associated with a direct block of ionic currents or inhibition of their trafficking from nucleus to cell membrane ENSG00000148798 ENSG00000146648 PMC4868481__F7 Both the EMP (red) and the OPP (blue) pathways share intermediates with the Calvin–Benson cycle (circled in red), but not the ED (green) pathway ENSG00000197713 PMC3914444__F2 Scheme of PI3K/PTEN/AKT signaling network activated by heterodimerization of HER2/HER3 receptors induced by heregulin (HRG) and inhibited by pertuzumab, 2C4 ENSG00000113905 PMC8558833__F9 Anatase and Rutile TiO2 Nanoparticles Lead Effective Bone Damage in Young Rat Model via the IGF-1 Signaling Pathway ENSG00000214285 ENSG00000140443 ENSG00000143387 PMC329503__F9 The roles of Ras and Mob2 in S ENSG00000196511 ENSG00000130234 ENSG00000163914 ENSG00000076641 ENSG00000291442 PMC6460507__F5 Notch and APP signalling pathways ENSG00000142192 ENSG00000137845 PMC4362832__F2 Standard pathway by which microRNAs are processed and loaded onto RISC to regulate gene expression ENSG00000128191 ENSG00000113360 PMC4362832__F1 Endocrine resistance in breast cancer cells ENSG00000077782 ENSG00000146648 PMC8700759__F5 C4d Deposition after Allogeneic Renal Transplantation in Rats Is Involved in Initial Apoptotic Cell Clearance ENSG00000111537 ENSG00000134982 PMC2814179__F1 Therapeutic targeting of NOTCH1 signaling in T-ALL ENSG00000283780 ENSG00000148400 ENSG00000137845 PMC4300045__F3 Gene ontology (GO) analysis using the DAVID software ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000182511 ENSG00000136997 ENSG00000123374 ENSG00000112378 ENSG00000164305 PMC8700759__F6 C4d Deposition after Allogeneic Renal Transplantation in Rats Is Involved in Initial Apoptotic Cell Clearance ENSG00000196954 ENSG00000067900 ENSG00000120868 ENSG00000148935 ENSG00000115317 PMC9263262__F1 MicroRNA/lncRNA Intertwined With the Wnt/Beta-Catenin Axis in Regulating the Pathogenesis of Triple-Negative Breast Cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4216940__F2 Majority of mitochondrial proteins/enzymes undergo reversible lysine acetylation ENSG00000171503 ENSG00000156467 ENSG00000062485 ENSG00000127884 PMC9520263__F3 Tumor resistance to immune checkpoint blockade and combination strategies to overcome resistance ENSG00000136869 ENSG00000168610 ENSG00000164342 PMC5989870__F1 Schematic diagram ENSG00000125398 ENSG00000137673 ENSG00000143867 ENSG00000134982 ENSG00000168036 PMC6449344__F1 CpgA is pivotal in prevention of 4PE-mediated metabolic gridlock ENSG00000261701 ENSG00000197713 ENSG00000198951 PMC6049507__F7 MiRNA and host targets are involved in common pathways ENSG00000066136 ENSG00000169032 ENSG00000118971 PMC7578260__F2 TRIM-mediated regulation of the TLR signaling pathway ENSG00000132109 ENSG00000112343 ENSG00000113595 ENSG00000204977 ENSG00000137699 ENSG00000171206 ENSG00000121236 ENSG00000116525 ENSG00000169871 ENSG00000276561 ENSG00000127445 ENSG00000100505 ENSG00000172005 ENSG00000134070 ENSG00000136869 ENSG00000157625 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 ENSG00000130726 PMC8101438__F2 MTOR signaling pathway and its role in metabolic programs and differentiation of T-cell subsets ENSG00000138378 ENSG00000002330 ENSG00000171150 ENSG00000112561 ENSG00000126353 ENSG00000084774 ENSG00000026103 PMC3675586__F1 Sugar nucleotide biosynthetic pathways identified in the genome of P ENSG00000069482 PMC4324580__F5 Proposed mechanism of action of glycyrrhetinic acid (GA)-induced G1-phase arrest in non-small cell lung cancer (NSCLC) cells ENSG00000228716 ENSG00000101945 ENSG00000144895 ENSG00000135446 ENSG00000132646 ENSG00000123374 ENSG00000105810 PMC8997602__F1 Impact of Lipid Metabolism on Antitumor Immune Response ENSG00000115415 ENSG00000140284 ENSG00000168610 PMC6341304__F1 Mitochondrial dysfunction and diabetic retinopathy PMC7704563__F8 Schematic overview of the distinct roles of p38A depending on the disease stages during NAFLD progression ENSG00000163739 ENSG00000171791 ENSG00000164305 PMC8097353__F1 Deubiquitinating enzyme USP42 stabilizes RNF43/ZNRF3 at the plasma membrane ENSG00000133067 ENSG00000183579 ENSG00000108375 ENSG00000106346 PMC2752535__F4 Common features of host-Flaviviridae interactions ENSG00000051523 ENSG00000284774 ENSG00000070814 ENSG00000291603 ENSG00000133937 ENSG00000060982 ENSG00000196504 ENSG00000114737 ENSG00000101266 ENSG00000116525 ENSG00000109689 ENSG00000183735 ENSG00000095777 ENSG00000009950 ENSG00000102226 ENSG00000066044 ENSG00000198742 ENSG00000291483 ENSG00000137203 ENSG00000037280 ENSG00000127337 ENSG00000185825 ENSG00000196367 ENSG00000158859 ENSG00000137834 ENSG00000074590 ENSG00000125148 ENSG00000291938 ENSG00000007866 ENSG00000213341 ENSG00000105568 ENSG00000006062 ENSG00000168610 ENSG00000181444 ENSG00000171303 ENSG00000157823 ENSG00000047056 ENSG00000136603 ENSG00000157110 ENSG00000163848 PMC7945298__F9 NcRNAs involved the PI3K-Akt signaling pathway ENSG00000204262 ENSG00000198793 ENSG00000141564 ENSG00000167965 ENSG00000112715 ENSG00000108821 ENSG00000124762 PMC6049507__F6 MiRNA targets in cancer pathways ENSG00000005339 PMC7945298__F8 Subnetwork of PVT1 and HOTAIR ENSG00000182481 ENSG00000087510 ENSG00000064601 ENSG00000167470 ENSG00000123728 ENSG00000175352 ENSG00000137699 ENSG00000129255 ENSG00000112715 ENSG00000124762 ENSG00000008083 ENSG00000106683 ENSG00000117525 ENSG00000135709 ENSG00000112245 ENSG00000154122 ENSG00000146072 ENSG00000167670 ENSG00000179431 ENSG00000108256 ENSG00000139687 ENSG00000158050 ENSG00000114554 ENSG00000087245 ENSG00000135414 ENSG00000124766 ENSG00000139926 ENSG00000095383 ENSG00000137266 ENSG00000136603 ENSG00000167123 ENSG00000172667 ENSG00000134247 ENSG00000103326 ENSG00000171848 ENSG00000029993 ENSG00000138180 PMC3674463__F1 EGFR pathway and downstream signaling pathways, including KRAS ENSG00000157764 ENSG00000146648 PMC3626681__F1 Molecular and biochemical studies in hyperlysinemia patients ENSG00000164904 ENSG00000179761 ENSG00000105607 ENSG00000127884 PMC8290102__F1 Streptococcus pneumoniae, S. pyogenes and S. agalactiae membrane phospholipid remodelling in response to human serum ENSG00000197471 ENSG00000173599 ENSG00000184207 ENSG00000182326 PMC6923788__F1 Signaling by the phosphatidylinositol-3-kinase (PI3K)-AKT- mammalian target of rapamycin (mTOR) pathway ENSG00000077782 PMC11510507__F5 Signaling pathway diagram of phagosome (the images are sourced from the DAVID database 2024 ENSG00000135218 ENSG00000170458 ENSG00000168818 ENSG00000136869 ENSG00000005381 ENSG00000274145 PMC6429784__F4 Schematic diagram for anti-ethanol caused damage in K ENSG00000157554 ENSG00000096088 PMC4278533__F4 Gene set variation analysis of the antigen processing and presentation pathway (APP) and the natural killer (NK) cell gene set ENSG00000168329 ENSG00000149294 ENSG00000127022 ENSG00000231925 ENSG00000180644 ENSG00000136213 ENSG00000100385 ENSG00000183734 ENSG00000174600 ENSG00000111537 ENSG00000067840 ENSG00000169583 ENSG00000115523 PMC7913835__F3 Protein–protein interaction network between gene products with high-impact variants contained in the top enriched pathways and those presenting differentially methylated sites in CLZ-treated patients ENSG00000006071 ENSG00000124140 ENSG00000259207 ENSG00000145863 ENSG00000136111 ENSG00000157193 ENSG00000198626 ENSG00000100346 ENSG00000087460 ENSG00000182256 ENSG00000117020 ENSG00000186472 ENSG00000008838 ENSG00000198838 ENSG00000183185 ENSG00000166501 ENSG00000185532 ENSG00000198010 ENSG00000080709 ENSG00000124181 ENSG00000143603 ENSG00000162104 ENSG00000156113 ENSG00000157542 PMC12021615__F4 Other E3s and DUBs in NAFLD ENSG00000145604 ENSG00000135655 ENSG00000131473 ENSG00000162711 ENSG00000111058 ENSG00000284774 ENSG00000055483 ENSG00000150907 ENSG00000169710 ENSG00000169871 ENSG00000075239 ENSG00000131828 PMC12021615__F3 E3s and DUBs in NAFLD-related ERS, mitochondrial malfunction, and lipid autophagy ENSG00000042832 ENSG00000144895 ENSG00000101255 ENSG00000130649 ENSG00000169710 ENSG00000189403 ENSG00000265972 ENSG00000178828 ENSG00000101557 PMC3855612__F4 Human myometrium differentially expresses mTOR signalling components before and during pregnancy: evidence for regulation by progesterone ENSG00000169047 ENSG00000198793 ENSG00000155792 ENSG00000164327 PMC12021615__F2 E3s and DUBs in SIRT, TGFB, JAK, TLR4 and STING signaling pathway in NAFLD ENSG00000124422 ENSG00000082996 ENSG00000142453 ENSG00000109654 ENSG00000136869 ENSG00000096717 ENSG00000189079 PMC12021615__F1 E3s and DUBs in TAK1, ASK1 and mTOR signaling pathway in NAFLD ENSG00000162711 ENSG00000129667 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000108654 ENSG00000197442 ENSG00000135341 ENSG00000184979 ENSG00000090432 ENSG00000131323 ENSG00000083799 ENSG00000175104 PMC5244594__F12 Working model of how the glucose dual-affinity transport system functions in glucose transport, signaling, and CCR ENSG00000138433 PMC5324334__F7 TSPC induces cell cycle G1 arrest probably mediated by CDKN1A and CDKN1B CKIs in a TP53-independent manner, while CDDP induces S and G2/M arrest via TP53/CDKN1A pathway in SK-MEL-5, and preventing dephosphorylation of CDK1 in both cell lines ENSG00000123374 ENSG00000124762 ENSG00000175305 PMC7309952__F6 Regulatory network of the BCL2 family in gynaecologic and breast cancer ENSG00000100290 ENSG00000136997 ENSG00000121879 ENSG00000127948 PMC8622331__F4 Bacterial Ghosts-Based Vaccine and Drug Delivery Systems ENSG00000174125 ENSG00000170458 ENSG00000187554 ENSG00000136869 ENSG00000091106 ENSG00000150455 PMC7343851__F7 SSP regulation of PI3K/Akt signaling pathway ENSG00000105656 ENSG00000164327 PMC4823950__F1 NGF FLIPs TrkA onto the death TRAIL in neuroblastoma cells ENSG00000132906 ENSG00000168040 ENSG00000164305 PMC8747764__F7 TPMT mRNA Expression: A Novel Prognostic Biomarker for Patients with Colon Cancer by Bioinformatics Analysis ENSG00000100522 ENSG00000142798 ENSG00000091409 ENSG00000164305 ENSG00000095380 ENSG00000169231 ENSG00000065833 ENSG00000105664 ENSG00000198380 ENSG00000186340 ENSG00000112699 ENSG00000108788 ENSG00000140443 ENSG00000026103 ENSG00000013375 ENSG00000112695 ENSG00000184983 ENSG00000254685 ENSG00000118680 ENSG00000124370 ENSG00000004779 ENSG00000172340 ENSG00000129007 ENSG00000178127 ENSG00000109390 ENSG00000213619 ENSG00000093144 ENSG00000184076 ENSG00000065615 ENSG00000072110 ENSG00000137076 ENSG00000082212 ENSG00000159399 PMC6323238__F1 Regulatory system of ERK1/2 signaling ENSG00000169291 ENSG00000138166 ENSG00000120875 ENSG00000171435 ENSG00000136997 ENSG00000141068 ENSG00000146648 ENSG00000158050 ENSG00000164086 PMC8322647__F1 Contemporary View of Natriuretic Peptides in the SARS-CoV-2 Era ENSG00000130234 ENSG00000214285 PMC4498564__F1 Heme biosynthetic pathway ENSG00000110711 ENSG00000144410 ENSG00000066926 ENSG00000188690 PMC4649622__F4 Dynamic changes in host gene expression associated with H5N8 avian influenza virus infection in mice ENSG00000068079 ENSG00000213928 ENSG00000105397 ENSG00000033800 ENSG00000157601 ENSG00000125347 ENSG00000230034 PMC12248764__F5 Fatty acid synthesis pathway in L ENSG00000069812 PMC4649622__F5 Dynamic changes in host gene expression associated with H5N8 avian influenza virus infection in mice ENSG00000160789 ENSG00000110330 ENSG00000102871 ENSG00000105939 ENSG00000168040 ENSG00000127191 ENSG00000111348 ENSG00000197694 ENSG00000148935 ENSG00000115317 ENSG00000276068 ENSG00000106683 ENSG00000183735 ENSG00000100813 ENSG00000026103 PMC4343025__F1 Genome organization and biogenesis of microRNAs (miRNAs) ENSG00000092847 ENSG00000128191 ENSG00000113360 ENSG00000134698 ENSG00000123908 ENSG00000132341 PMC5000672__F6 Proposed signal pathway activated by HMDB in HeLa cervical cancer cells ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 PMC8997602__F4 Impact of Lipid Metabolism on Antitumor Immune Response ENSG00000089692 PMC7500051__F5 Opposite immune effects of M1-like and M2-like TAMs in the tumor microenvironment ENSG00000102962 ENSG00000111537 ENSG00000172216 ENSG00000118520 ENSG00000049768 ENSG00000115009 PMC10243463__F1 BMP4 signaling in trophoblast emergence from pluripotency ENSG00000107779 ENSG00000121989 ENSG00000123612 ENSG00000204217 ENSG00000114739 PMC5702246__F6 The PTHLH/PTH1R-ATF2 negative-feedback loop ENSG00000132478 PMC3364790__F4 Boswellic acid induces epigenetic alterations by modulating DNA methylation in colorectal cancer cells ENSG00000186051 ENSG00000135373 PMC11046856__F4 Crosstalk between Wnt/Beta-catenin, Notch, and TGFB signaling pathways during wound healing ENSG00000112715 ENSG00000108821 ENSG00000114315 ENSG00000168646 PMC9179857__F3 Loss of CHGA Protein as a Potential Biomarker for Colon Cancer Diagnosis: A Study on Biomarker Discovery by Machine Learning and Confirmation by Immunohistochemistry in Colorectal Cancer Tissue Microarrays ENSG00000151490 ENSG00000113140 ENSG00000148175 PMC11046856__F2 Non-canonical Wnt signaling pathways ENSG00000169071 ENSG00000177606 PMC11046856__F1 Canonical Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC7017008__F2 Main molecular mechanisms underlying EMT activation ENSG00000019991 ENSG00000122691 ENSG00000138798 ENSG00000163914 ENSG00000168610 PMC6476857__F12 Graphical abstract shows the protective mechanism of SFN against Ar-induced damage in the kidney tissue via PI3K/Akt-mediated Nrf2 signaling pathway ENSG00000175793 ENSG00000079999 PMC6277854__F2 Major signaling pathways and therapeutic targets in CLL cells ENSG00000138795 ENSG00000002330 ENSG00000186716 ENSG00000163914 ENSG00000177606 ENSG00000136997 ENSG00000168036 ENSG00000100985 ENSG00000010671 ENSG00000121966 PMC8580341__F4 Differential expression of long non-coding RNAs as diagnostic markers for lung cancer and other malignant tumors ENSG00000105397 ENSG00000137193 ENSG00000171791 ENSG00000168610 ENSG00000136826 PMC8580341__F3 Differential expression of long non-coding RNAs as diagnostic markers for lung cancer and other malignant tumors ENSG00000260027 ENSG00000169291 PMC8580341__F2 Differential expression of long non-coding RNAs as diagnostic markers for lung cancer and other malignant tumors ENSG00000087095 ENSG00000134982 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000102974 PMC8529754__F2 An update on extra-oral bitter taste receptors ENSG00000185933 ENSG00000183128 ENSG00000070985 ENSG00000137841 PMC5777140__F5 Blood genome-wide transcriptional profiles reflect broad molecular impairments and strong blood-brain links in Alzheimer’s disease ENSG00000136457 ENSG00000135218 ENSG00000168743 ENSG00000110799 ENSG00000026508 PMC8580341__F6 Differential expression of long non-coding RNAs as diagnostic markers for lung cancer and other malignant tumors ENSG00000002330 PMC7559526__F8 Melanin synthesis pathway related genes in dorsal and ventral skin of LBM ducks ENSG00000101440 ENSG00000115138 PMC7565286__F1 Summary diagram of transport, signaling and degradation of vitamin A metabolism and RA synthesis ENSG00000184254 ENSG00000138207 ENSG00000128918 ENSG00000162496 PMC8580341__F5 Differential expression of long non-coding RNAs as diagnostic markers for lung cancer and other malignant tumors ENSG00000096717 PMC9343736__F3 Endothelial cells in vascular calcification ENSG00000150782 ENSG00000111341 PMC7039698__F1 Topical cholesterol/lovastatin for the treatment of porokeratosis: a pathogenesis-directed therapy ENSG00000160752 ENSG00000067064 ENSG00000110921 ENSG00000112972 ENSG00000152904 ENSG00000113161 ENSG00000120437 ENSG00000167508 ENSG00000075239 ENSG00000148377 PMC5951830__F7 Metabolism of bicarbonate and t6A37 formation in cytoplasm and mitochondria ENSG00000196449 ENSG00000128694 PMC5882218__F1 Models of the Hippo pathway in mammals ENSG00000150457 ENSG00000131023 PMC6037882__F4 Role of mucins in CSCs ENSG00000145113 PMC5325457__F5 Ubc13: the Lys63 ubiquitin chain building machine ENSG00000102871 ENSG00000157625 ENSG00000131323 ENSG00000168040 ENSG00000175104 ENSG00000127191 ENSG00000184216 ENSG00000112130 PMC11853667__F1 mTOR signaling pathway in cells ENSG00000154342 ENSG00000177169 ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC7013532__F1 Pathway associated with terpene synthesis in Camellia sinensis ENSG00000110921 ENSG00000197429 ENSG00000026103 PMC9416350__F2 Peptide-Based Vaccines in Clinical Phases and New Potential Therapeutic Targets as a New Approach for Breast Cancer: A Review ENSG00000169248 ENSG00000169245 ENSG00000138755 ENSG00000277943 PMC7048048__F2 Directionality of transketolase 2 (TKT2) impacts the in silico essentiality of two genes encoding EDD and EDA from the Entner–Doudoroff pathway ENSG00000197713 PMC7048048__F1 Core networks generated by the redGEM algorithm from iJN1411 genome-scale model ENSG00000197713 ENSG00000173599 ENSG00000172005 ENSG00000008130 ENSG00000082212 ENSG00000062485 PMC7229984__F1 Retrospective clinical trial experimentally validates glioblastoma genome-wide pattern of DNA copy-number alterations predictor of survival ENSG00000117020 ENSG00000146872 ENSG00000106571 ENSG00000073614 ENSG00000135446 ENSG00000205155 ENSG00000270629 ENSG00000164690 ENSG00000128602 ENSG00000146648 ENSG00000090932 ENSG00000198625 PMC9224267__F2 EGFR-Mutated Non-Small Cell Lung Cancer and Resistance to Immunotherapy: Role of the Tumor Microenvironment ENSG00000168610 ENSG00000146648 PMC6248540__F2 Pathway analysis infers molecular pathway of relapse ENSG00000042832 ENSG00000163914 ENSG00000026508 ENSG00000153317 PMC2975936__F1 Classical pathway of complement activation by antibody ENSG00000244731 ENSG00000236625 PMC8192181__F5 Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NFKB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways ENSG00000169245 ENSG00000168610 PMC8063837__F2 Models of signaling in Hedgehog pathway activation in cancer ENSG00000115008 ENSG00000125538 ENSG00000128602 PMC7401422__F3 Visualization of the cell cycle pathway from WikiPathways ENSG00000132646 ENSG00000100479 ENSG00000177084 PMC6209826__F10 We observed that chlorogenic acid showed binding affinity to interact with ctDNA, VEGF and VEGF receptors ENSG00000100234 ENSG00000087245 ENSG00000105329 ENSG00000198793 ENSG00000112715 ENSG00000121879 ENSG00000150782 ENSG00000157150 ENSG00000157227 ENSG00000149968 ENSG00000128052 ENSG00000177606 ENSG00000150907 ENSG00000100985 ENSG00000171608 ENSG00000146648 ENSG00000150630 PMC8063837__F1 Hedgehog signaling pathway and its possible inhibitions ENSG00000143147 ENSG00000144857 ENSG00000128602 PMC4621741__F1 Mutant SPOP promotes genomic rearrangements within chromosomes ENSG00000121067 ENSG00000135341 PMC10302997__F1 Emerging role of autophagy in colorectal cancer: Progress and prospects for clinical intervention ENSG00000124102 ENSG00000177169 ENSG00000152348 ENSG00000198382 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC5732091__F6 CHOLANGIOCYTE PRIMARY CILIUM IN HEALTH AND DISEASE ENSG00000134982 ENSG00000168036 ENSG00000132478 PMC3924769__F6 DAF-12, a nuclear hormone receptor regulating development and lifespan ENSG00000196839 ENSG00000099377 ENSG00000135929 PMC3961794__F1 Mononuclear Phagocyte System in Homeostasis and Disease: A Role for Heme Oxygenase-1 ENSG00000105397 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC3294814__F1 Proposed biosynthetic pathway of RQ (compound 1) ENSG00000132423 ENSG00000119723 ENSG00000110871 ENSG00000173085 ENSG00000167186 PMC4849794__F7 Rotenone Susceptibility Phenotype in Olfactory Derived Patient Cells as a Model of Idiopathic Parkinson’s Disease ENSG00000115415 ENSG00000177606 ENSG00000205250 PMC6025799__F2 Roles of IGF2BP1 in promoting and suppressing tumor growth and invasion via regulating different mRNA targets, under the modulation of upstream non-coding RNAs ENSG00000148773 ENSG00000141639 ENSG00000026508 ENSG00000117152 ENSG00000166278 ENSG00000073756 PMC3063194__F1 Elicitation of innate immune response in EBV infection ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000131323 ENSG00000276561 ENSG00000164342 PMC4694849__F4 PI3K/AKT/mTOR pathway is a potential predictor of distinct invasive and migratory capacities in human ovarian cancer cell lines ENSG00000198793 ENSG00000166501 ENSG00000121879 ENSG00000171608 PMC10299455__F2 NOTCH signaling pathway, ligands, and inhibitors ENSG00000168214 ENSG00000010810 ENSG00000136997 ENSG00000114315 PMC3127069__F1 The mTOR-signalling pathway from growth factor receptor through mTOR ENSG00000198793 PMC8869290__F1 Oligomannose-Type Glycan Processing in the Endoplasmic Reticulum and Its Importance in Misfolding Diseases ENSG00000136731 ENSG00000134109 ENSG00000116406 ENSG00000088298 PMC3281277__F1 Proteolytic processing of the BACE1 substrates APP and NRG1 ENSG00000138798 ENSG00000137845 PMC5882331__F2 Therapeutic targets of TP53 gene in the context of its classically canonical functions and its latest non-canonical functions in human cancer ENSG00000149311 ENSG00000175054 ENSG00000078237 ENSG00000284194 PMC3063194__F2 Evasion of immune responses by individual EBV products ENSG00000169248 ENSG00000213928 ENSG00000137265 ENSG00000168040 ENSG00000164305 ENSG00000276561 ENSG00000026103 PMC6326993__F2 Schematic overview on a striatal medium spiny neuron synapse PMC8259786__F4 NOTCH Signaling in Aortic Valve Development and Calcific Aortic Valve Disease ENSG00000125398 ENSG00000111341 PMC8259786__F3 NOTCH Signaling in Aortic Valve Development and Calcific Aortic Valve Disease ENSG00000162552 ENSG00000148400 ENSG00000113070 ENSG00000168036 PMC8259786__F2 NOTCH Signaling in Aortic Valve Development and Calcific Aortic Valve Disease ENSG00000125266 ENSG00000168214 ENSG00000128917 ENSG00000090932 ENSG00000124762 PMC8869508__F3 Interplay of Hypoxia Signaling on Mitochondrial Dysfunction and Inflammation in Cardiovascular Diseases and Cancer: From Molecular Mechanisms to Therapeutic Approaches ENSG00000162711 ENSG00000088888 ENSG00000125538 ENSG00000160703 ENSG00000091106 PMC3706396__F6 S100A8/A9 (Calprotectin) Negatively Regulates G2/M Cell Cycle Progression and Growth of Squamous Cell Carcinoma ENSG00000143546 ENSG00000134057 ENSG00000163220 ENSG00000123374 PMC6587703__F2 Mechanistic interactions between VEGF-targeted anti-angiogenic therapy and checkpoint inhibitors in the systemic treatment of mRCC ENSG00000134086 ENSG00000069482 ENSG00000070831 ENSG00000163235 PMC4865041__F7 Generating Gene Ontology-Disease Inferences to Explore Mechanisms of Human Disease at the Comparative Toxicogenomics Database ENSG00000143799 ENSG00000112530 ENSG00000171791 PMC6336016__F2 Application of built-in adjuvants for epitope-based vaccines ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC7568023__F2 Engineered nanomaterials as fighters against SARS-CoV-2: The way to control and treat pandemics ENSG00000130234 ENSG00000214285 ENSG00000236625 PMC4159649__F6 Identified glycotransferases involved in O-glycosylation and associated biosynthetic pathway ENSG00000167080 ENSG00000121578 ENSG00000069482 ENSG00000135702 ENSG00000183778 ENSG00000130383 ENSG00000154252 ENSG00000198488 ENSG00000140297 ENSG00000179913 PMC3697962__F2 Insulin-like signaling pathway ENSG00000171105 PMC8666273__F5 Runx3 regulates iron metabolism via modulation of BMP signalling ENSG00000105697 ENSG00000020633 PMC8036928__F3 Antioxidant metabolism in circulating tumour cells (CTC) ENSG00000065833 ENSG00000172005 PMC9483553__F2 Prominent Role of miR-942 in Carcinogenesis of Tumors ENSG00000134982 ENSG00000106483 ENSG00000168062 ENSG00000103449 ENSG00000052850 ENSG00000158290 ENSG00000180447 ENSG00000048392 ENSG00000162676 ENSG00000095739 ENSG00000150672 ENSG00000196263 ENSG00000165471 PMC11797775__F2 The main cell signalling pathway mechanisms reportedly disrupted by hyperglycaemia-associated oxidative stress and AGEs in MSCs, osteoblasts and osteocytes, potentially contributing to impaired bone healing in T2DM patients ENSG00000134982 ENSG00000198793 PMC4664460__F3 Commonalities between pain and memory mechanisms and their meaning for understanding chronic pain PMC8656569__F1 miRNAs in the Regulation of Cancer Immune Response: Effect of miRNAs on Cancer Immunotherapy ENSG00000102871 ENSG00000172936 ENSG00000083799 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC9327201__F4 Reprogramming of glutamine metabolism and its impact on immune response in the tumor microenvironment ENSG00000108342 ENSG00000115419 PMC3351343__F6 Working model for onset of emphysema in Fut8+/− mice upon exposure to CS PMC3734825__F7 Upregulation of HSP70 and the phosphorylation of STAT1 induced by bortezomib (BTZ) decrease the cytotoxic activity against ovarian cancer cells ENSG00000284774 ENSG00000002330 ENSG00000115415 PMC5932138__F6A Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin–Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H–Related Protein-5 (FHR5) Deposition ENSG00000013441 ENSG00000236625 PMC8502867__F2 Safe Path at the Fork: Ensuring Replication-Associated DNA Double-Strand Breaks are Repaired by Homologous Recombination ENSG00000197774 ENSG00000164306 ENSG00000051180 ENSG00000198056 ENSG00000122547 ENSG00000138385 PMC8960495__F9 In utero exposure to electronic-cigarette aerosols decreases lung fibrillar collagen content, increases Newtonian resistance and induces sex-specific molecular signatures in neonatal mice ENSG00000087586 ENSG00000185917 ENSG00000284984 PMC2475726__F10 F igure 10.— PMC8960495__F7 In utero exposure to electronic-cigarette aerosols decreases lung fibrillar collagen content, increases Newtonian resistance and induces sex-specific molecular signatures in neonatal mice ENSG00000050165 ENSG00000150764 ENSG00000284984 PMC11016009__F4 B7-H3 at the crossroads between tumor plasticity and colorectal cancer progression: a potential target for therapeutic intervention ENSG00000131015 ENSG00000168610 PMC5913290__F1 Key elements in the DNA damage response (DDR) pathway ENSG00000149311 ENSG00000175054 ENSG00000138385 PMC4246027__F1 NEUROTROPHINS IN THE VENTRAL TEGMENTAL AREA: ROLE IN SOCIAL STRESS, MOOD DISORDERS AND DRUG ABUSE ENSG00000175104 ENSG00000076604 PMC8387624__F5 Functions of Hepatitis B Virus Encoding Proteins: Viral Persistence and Liver Pathogenesis ENSG00000168036 ENSG00000179750 ENSG00000123374 ENSG00000168610 PMC8387624__F4 Functions of Hepatitis B Virus Encoding Proteins: Viral Persistence and Liver Pathogenesis ENSG00000087245 ENSG00000178764 ENSG00000078668 ENSG00000150907 ENSG00000169136 ENSG00000198793 ENSG00000168036 ENSG00000185591 ENSG00000100985 ENSG00000168610 PMC8574196__F3 ApoE and AB interaction ENSG00000130164 PMC6518354__F1 Schematic drawing presents the detail signaling pathways of endometrial carcinogenesis ENSG00000002330 ENSG00000291971 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000168036 PMC7127985__F1 Molecular pathways involved in PKD, autophagy and apoptosis ENSG00000177169 ENSG00000002330 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000186654 PMC8194326__F1 T follicular helper cells: linking cancer immunotherapy and immune-related adverse events PMC6130072__F2 Transcription factor interactions in endothelial cell functions ENSG00000105672 ENSG00000176692 ENSG00000150907 ENSG00000163914 PMC9338502__F3 Bioinformatics analysis and experimental verification of Notch signalling pathway-related miRNA–mRNA subnetwork in extracellular vesicles during Echinococcus granulosus encystation ENSG00000273529 ENSG00000133961 ENSG00000114315 PMC7793262__F2 Systems biology predicts that fibrosis in tuberculous granulomas may arise through macrophage-to-myofibroblast transformation ENSG00000111537 ENSG00000115415 ENSG00000168610 PMC4963951__F2 The roles of monocytes and polarized macrophages in HTS formation ENSG00000118520 ENSG00000168610 ENSG00000121966 ENSG00000007171 PMC2818240__F5 Oxidative stress and glutathione in TGF-Beta-mediated fibrogenesis ENSG00000185591 PMC3414727__F2 AKT/mTOR signaling and crosstalk with glycolysis and mitochondrial oxidative phosphorylation PMC9556184__F1 Potential Role of Voltage-Dependent Anion Channel in the Treatment of Parkinson's Disease ENSG00000078668 ENSG00000158828 PMC408363__F1 Complexity of the CD28/CD152–B7-1/B7-2 T-cell costimulatory pathway ENSG00000134982 ENSG00000163599 PMC3414727__F1 AKT/mTOR signaling pathway ENSG00000177169 ENSG00000149212 ENSG00000002330 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC8510628__F1 Formyl Peptide Receptors in Neurological Diseases via Regulating Inflammation ENSG00000291971 ENSG00000125538 PMC2949778__F1 Folate metabolic pathway ENSG00000124275 ENSG00000035928 ENSG00000116984 PMC5359927__F1 Main signaling pathways involved in vasculogenic mimicry ENSG00000087245 ENSG00000142627 ENSG00000122691 ENSG00000157227 ENSG00000241186 ENSG00000156574 PMC6990917__F8 Mechanism of the protective effect of fenofibrate against diabetic nephropathy ENSG00000181019 ENSG00000105550 ENSG00000010810 PMC3536591__F2 Ingenuity pathway analysis (IPA) top network that incorporates 9 genes identified as differentially methylated between methotrexate-naïve cases and controls by HM27 analysis ENSG00000180228 ENSG00000144895 ENSG00000117400 ENSG00000139546 ENSG00000136997 ENSG00000189308 ENSG00000100739 ENSG00000143556 ENSG00000121764 ENSG00000101680 ENSG00000175305 PMC7758122__F4 Cross-talks between seven primary regulatory pathways of RDNI for inflammation ENSG00000198626 ENSG00000073756 PMC7709275__F1 Role of the unfolded protein response (UPR) in cancer ENSG00000128272 ENSG00000144895 PMC5893845__F6 Schematic diagram on the transcriptomic profiles of metabolic pathway genes involved in the enhanced MCFA production of mutant cC14TE_B3 D ENSG00000159224 ENSG00000138433 PMC7709275__F3 MiRNAs regulate tumor characteristics including apoptosis, invasion, EMT, and metastasis by regulating the UPR ENSG00000124216 ENSG00000128272 ENSG00000144895 ENSG00000078081 ENSG00000177606 ENSG00000189403 ENSG00000130513 ENSG00000104723 PMC8222490__F2 Molecular alterations in oral cancer using high-throughput proteomic analysis of formalin-fixed paraffin-embedded tissue ENSG00000135218 ENSG00000142798 ENSG00000168743 ENSG00000110799 ENSG00000150093 ENSG00000091409 ENSG00000072571 ENSG00000136457 ENSG00000213949 ENSG00000169704 ENSG00000105664 ENSG00000041982 ENSG00000029559 ENSG00000278316 ENSG00000188157 ENSG00000203618 ENSG00000152592 ENSG00000108821 ENSG00000139626 ENSG00000259207 ENSG00000005961 ENSG00000189056 ENSG00000115221 ENSG00000164171 ENSG00000138759 ENSG00000173402 ENSG00000115884 ENSG00000122012 ENSG00000118785 ENSG00000164946 ENSG00000178732 ENSG00000026508 ENSG00000135424 ENSG00000115232 PMC7709275__F5 LncRNAs regulate the tumor characteristics apoptosis (a), invasion and metastasis (b), and metabolism (c) by regulating the UPR ENSG00000128272 ENSG00000144895 ENSG00000269858 PMC6735501__F1 Initiating events in autophagy ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000196455 ENSG00000023287 ENSG00000144848 ENSG00000284099 ENSG00000145782 ENSG00000057663 PMC3440368__F7 Disturbed Relaxin Signaling Pathway and Testicular Dysfunction in Mouse Offspring upon Maternal Exposure to Simazine ENSG00000100985 ENSG00000007171 PMC10538757__F2 STRING analysis of protein–protein interactions ENSG00000021776 ENSG00000002330 ENSG00000086589 ENSG00000110107 ENSG00000148400 ENSG00000117614 ENSG00000036672 ENSG00000172005 ENSG00000162924 ENSG00000168610 PMC8355346__F1 Molecular mechanisms and signaling pathways of ferroptosis interact with AS ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000105697 ENSG00000136869 ENSG00000162772 PMC5748821__F1 Nuclear factor-E2-related factor 2 (NRF2) pathway with a focus on skin barrier function and environmental stress protection ENSG00000151012 ENSG00000124107 ENSG00000171791 ENSG00000067369 ENSG00000023909 ENSG00000124762 ENSG00000057663 ENSG00000079999 ENSG00000065833 ENSG00000182585 ENSG00000181019 ENSG00000100387 ENSG00000284099 ENSG00000271303 ENSG00000051180 PMC5587385__F7 InterferonA Negatively Regulates the Expression of Endothelial Nitric Oxide Synthase and Nitric Oxide Production: Implications for SLE ENSG00000169047 ENSG00000162692 PMC6601327__F6 Proposed model of OLFM4‐induced STAT3 activation mediated by the LGR5‐Wnt signaling pathway in HCC ENSG00000102837 ENSG00000134982 ENSG00000168610 PMC11120359__F1 Representation of the signaling pathway in the activation of CXCR4 (left) and ACKR3 (right) ENSG00000107562 ENSG00000198793 ENSG00000144476 ENSG00000121966 PMC7426575__F5 Schematic Model for Major Immune Escape-Initiating Domains and Immune Escape Points in Tumor-T Cell Interaction(A) Major immune escape points depicted in schematic model, highlighting tumor-T cell interaction at last stage of cancer-immunity cycle ENSG00000186810 ENSG00000111537 ENSG00000138755 PMC5789323__F2 Simplified relationship between ROS-induced redox signaling and mitochondrial dynamics ENSG00000079999 PMC7859329__F2 Thyroid hormones, Wnt pathway, and miRNAs crosstalk ENSG00000104371 ENSG00000168036 ENSG00000108510 PMC10218387__F3 Major pathways of carbon and energy metabolism in M382 ENSG00000113492 ENSG00000261857 ENSG00000128602 PMC3733085__F2 Simplified scheme of the pathways of complement activation ENSG00000288512 ENSG00000196352 ENSG00000117335 ENSG00000182326 PMC2844310__F3 Relationship of NFKB to genes identified as “linearly” changing with age on the basis of cocitation analysis (Genomatix BibliosphereTM) is shown as a Bibliosphere image ENSG00000122882 ENSG00000109320 ENSG00000131477 ENSG00000161270 PMC5966807__F4 A schematic showing the proposed signaling pathways in type II cells activated by neurochemicals at the carotid body sensory synapse ENSG00000187837 ENSG00000110218 PMC2680180__F1 Mitochondria—A Nexus for Aging, Calorie Restriction, and Sirtuins? ENSG00000124523 ENSG00000142082 ENSG00000089163 PMC9318003__F2 Will We Unlock the Benefit of Metformin for Patients with Lung Cancer? Lessons from Current Evidence and New Hypotheses ENSG00000138798 ENSG00000198793 ENSG00000096717 PMC5693226__F1 Rationale for mTOR inhibitor + NOTCH inhibitor combination ENSG00000132541 ENSG00000128917 ENSG00000198793 ENSG00000114315 PMC8168945__F1 Cholesterol Contributes to Male Sex Differentiation Through Its Developmental Role in Androgen Synthesis and Hedgehog Signaling ENSG00000132196 ENSG00000001630 ENSG00000116133 ENSG00000172893 ENSG00000109929 PMC5457688__F4 Précis of signaling pathways involved in glioma and inhibition by mTOR, AKT, PI3K and ERK inhibitors and genetic configuration of TSC1 and TSC2 ENSG00000198793 PMC8168945__F6 Cholesterol Contributes to Male Sex Differentiation Through Its Developmental Role in Androgen Synthesis and Hedgehog Signaling ENSG00000164690 ENSG00000139549 ENSG00000163501 PMC11307883__F3 Metabolic pathways of the microRNAs and their target genes ENSG00000145604 ENSG00000135423 ENSG00000119535 ENSG00000135446 ENSG00000113558 ENSG00000123374 ENSG00000105810 ENSG00000139687 ENSG00000084774 PMC6562905__F2 Role for fibroblast-derived metabolites in tumor-stroma interactions ENSG00000181026 PMC9585453__F4 Systematic review of the research progress of non-coding RNA in neuroinflammation and immune regulation in cerebral infarction/ischemia-reperfusion injury ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9496700__F1 Emerging Roles of miRNA, lncRNA, circRNA, and Their Cross-Talk in Pituitary Adenoma ENSG00000134057 ENSG00000125844 ENSG00000198793 ENSG00000135333 ENSG00000185885 ENSG00000253352 ENSG00000088992 PMC6431727__F5 RANKL-RANK signaling pathway via Btk in osteoclast differentiationTec family kinases are activated by RANK and bind to scaffolding proteins (BLNK or SLP76) activated by ITAM signaling, thereby forming a complex that cooperates to activate PLCG2 ENSG00000095585 ENSG00000197943 ENSG00000131196 ENSG00000135605 ENSG00000010671 PMC2440410__F3 Regulation of post-cushion valve maturation to thin fibrous leaflets also includes EGF receptor signalling in addition to differential signalling of the pathways in c ENSG00000170365 ENSG00000137834 ENSG00000065361 ENSG00000113070 ENSG00000138798 ENSG00000146648 ENSG00000178568 PMC10671144__F7 Network analysis of oxaliplatin revealed that oxaliplatin as a master regulator was predicted to be inhibited and the SPINK1 pancreatic cancer pathway was inactivated in ischemic cardiomyopathy ENSG00000274247 ENSG00000105329 ENSG00000164251 ENSG00000137392 ENSG00000284099 ENSG00000164266 ENSG00000154646 PMC10671144__F1 Carboplatin molecular network in cancer ENSG00000012048 ENSG00000109320 ENSG00000139515 ENSG00000177606 ENSG00000173039 ENSG00000073861 ENSG00000124762 PMC10671144__F3 Upstream regulator analysis of cisplatin revealed the upregulation in FAS, PRKCA, and CDKN1A, and involvement of tumor microenvironment pathway (lung adenocarcinoma (LUAD) [lung] cisplatin 9800) ENSG00000159388 ENSG00000177954 ENSG00000116717 ENSG00000162772 PMC4889031__F1 Deletion of ERA in uterine epithelial cells leads to infertility, however, this receptor loss does not prevent estrogen induced epithelial cell proliferation () ENSG00000138798 ENSG00000128342 ENSG00000168610 ENSG00000146648 ENSG00000140443 PMC4821530__F5 GUIdock: Using Docker Containers with a Common Graphics User Interface to Address the Reproducibility of Research ENSG00000169249 ENSG00000157764 ENSG00000099995 ENSG00000121067 ENSG00000100219 ENSG00000121879 ENSG00000099942 ENSG00000196712 ENSG00000126012 ENSG00000123124 PMC8535854__F1 Metabolic reprogramming orchestrates primary tumor cell invasion and supports PMN priming via exosomes ENSG00000144848 PMC5900707__F1 Schematic diagram of RIPK1 domains, interacting proteins, post-translational modifications, and the catalytic enzymes that read or write these modifications ENSG00000123240 ENSG00000137275 ENSG00000102871 ENSG00000083799 ENSG00000127191 ENSG00000285379 PMC8535854__F2 Metabolic changes allow cancer cells to survive in circulation and promote colonization of distant organs ENSG00000291971 ENSG00000100033 PMC6096407__F5 Several lncRNAs work at the post-transcriptional level as competing endogenous RNAs for microRNAs, titrating microRNA effector complexes away from their mRNA targets (e.g ENSG00000096717 PMC6096407__F4 LncRNAs can regulate gene expression by participating in chromatin looping (e.g ENSG00000183734 ENSG00000168036 ENSG00000196628 PMC6096407__F1 Several lncRNAs interact with transcription factors recruiting them to their target genes (e.g ENSG00000168036 ENSG00000196628 PMC8843871__F3 Paradoxical functions of long noncoding RNAs in hepatocellular carcinoma: Implications in therapeutic opportunities and precision medicine ENSG00000182718 ENSG00000221914 ENSG00000168036 ENSG00000139842 ENSG00000111641 PMC6627906__F1 Signaling pathways and receptors involved in uveal melanoma (UM) and cutaneous melanoma (CM) ENSG00000019991 ENSG00000107562 ENSG00000157764 ENSG00000198793 ENSG00000088256 ENSG00000121966 ENSG00000140443 PMC6096407__F3 LncRNAs activate (e.g ENSG00000215021 ENSG00000168036 PMC6096407__F2 Several lncRNAs bind to specific combinations of regulatory proteins, potentially acting as scaffold elements within ribonucleoprotein complexes, stabilizing their targets (e.g ENSG00000165119 ENSG00000168036 ENSG00000105810 ENSG00000168646 ENSG00000196628 PMC2746247__F1 Pathway Engineered Enzymatic de novo Purine Nucleotide Synthesis ENSG00000124479 ENSG00000146676 PMC5900707__F2 Activation of TNFR1 may promote multiple alternative signaling pathways, including the activation of NFKB, RIPK1-independent apoptosis (RIA), RDA, and necroptosis ENSG00000137275 ENSG00000102871 ENSG00000082512 ENSG00000157625 ENSG00000083799 ENSG00000168040 ENSG00000127191 ENSG00000285379 PMC10519225__F5 Genome-Wide Association Study of Alopecia Areata in Taiwan: The Conflict Between Individuals and Hair Follicles ENSG00000273686 ENSG00000115718 PMC6862675__F4 IPA® analysis of signalling pathways of the genes differentially expressed upon lysozyme treatment ENSG00000121931 ENSG00000090104 ENSG00000150991 ENSG00000011422 ENSG00000010810 ENSG00000148926 ENSG00000136694 ENSG00000130283 ENSG00000121774 PMC6518697__F6 Tenascin-C expression contributes to pediatric brainstem glioma tumor phenotype and represents a novel biomarker of disease ENSG00000134775 ENSG00000134339 ENSG00000183914 ENSG00000110711 ENSG00000135547 ENSG00000138346 ENSG00000137673 ENSG00000127528 ENSG00000112715 ENSG00000168961 ENSG00000146197 ENSG00000168610 ENSG00000106003 ENSG00000099617 ENSG00000041982 ENSG00000132692 ENSG00000134853 ENSG00000164266 ENSG00000154188 PMC7026191__F3 CEACAM3 signaling connections ENSG00000187796 ENSG00000170956 ENSG00000291971 PMC11302569__F3 Four key mechanisms of gut microbiome associated with the occurrence and progression of colorectal cancer a ENSG00000019991 ENSG00000142192 ENSG00000112486 PMC6252326__F1 Schematic representation of the tryptophan metabolism pathway PMC4935337__F6 Proposed model for the action of KP-A021 on the RANK signaling pathways in osteoclast differentiation, bone resorption, and cytoskeletal rearrangement ENSG00000291971 ENSG00000175104 ENSG00000127191 ENSG00000131196 PMC2606944__F9 Role of Small GTPases and AvB5 Integrin in Pseudomonas aeruginosa–Induced Increase in Lung Endothelial Permeability ENSG00000168036 PMC7876385__F3 Major mechanisms of drug resistance in BCSCs ENSG00000281324 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000118777 ENSG00000168610 PMC7876385__F4 Novel strategies of drug resistance reversal in BCSCs ENSG00000168036 ENSG00000164327 ENSG00000164690 ENSG00000171791 ENSG00000139549 ENSG00000168040 ENSG00000128602 ENSG00000118777 PMC5482964__F3 Signal transduction by BG ENSG00000183735 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC11434829__F1 Simplified overview of the omega-6 and omega-3 PUFAs metabolism, focusing on the AA metabolic pathway components with relevance in CF ENSG00000283887 PMC6940896__F13 A sketch map of immunoregulatory induced by LTAa ENSG00000125538 ENSG00000172936 ENSG00000175104 PMC9051099__F8 MyD88 signaling in HSCs in fibrosis model ENSG00000169245 ENSG00000186810 ENSG00000115415 ENSG00000172936 ENSG00000007171 PMC8899859__F10 Obstructive Sleep Apnea Affects Lacrimal Gland Function ENSG00000135218 ENSG00000026103 PMC9208186__F7 Blockade of the Arid5a/IL-6/STAT3 axis underlies the anti-inflammatory effect of Rbpjl in acute pancreatitis ENSG00000196843 ENSG00000168214 ENSG00000125538 ENSG00000168610 PMC4490005__F3 Vav1 regulates T cell activation through a feedback mechanism and crosstalk between the T cell receptor and CD28 ENSG00000010810 ENSG00000177606 ENSG00000162924 ENSG00000113263 ENSG00000124181 ENSG00000141968 PMC7016661__F2 TNF-TNFR2 signaling pathway ENSG00000137275 ENSG00000127191 PMC7300552__F1 ACE2 function and its regulation in severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection ENSG00000175054 ENSG00000130234 ENSG00000184012 PMC4306584__F7 Extracellular Hsp90 mediates an NFKB dependent inflammatory stromal program: Implications for the prostate tumor microenvironment ENSG00000173039 ENSG00000168610 PMC11009184__F7 Translatability of mouse muscle-aging for humans: the role of sex ENSG00000117020 ENSG00000133056 ENSG00000169047 ENSG00000198793 PMC11843152__F7 NCAPH Promotes the Proliferation of Prostate Cancer Cells Via Modulating the E2F1 Mediated PI3K/AKT/mTOR Axis ENSG00000134057 ENSG00000198793 PMC3309942__F1 Interaction motifs and domains of RANKL signal intermediaries ENSG00000121058 ENSG00000175104 ENSG00000159335 PMC10216531__F1 The fundamental parts of TLR4 signaling ENSG00000183735 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000285379 PMC5842063__F1 METABOLIC SWITCHING AND CELL FATE DECISIONS: IMPLICATIONS FOR PLURIPOTENCY, REPROGRAMMING AND DEVELOPMENT ENSG00000178860 ENSG00000136997 ENSG00000128342 ENSG00000096717 ENSG00000136826 PMC4291019__F6 ARF6 inhibition stabilizes the vasculature and enhances survival during endotoxic shock ENSG00000172936 ENSG00000165527 ENSG00000150455 PMC3309942__F2 p62 in osteoclast signaling and protein trafficking ENSG00000083799 ENSG00000175104 PMC4053506__F8 D-PDMP inhibits ox-LDL induced LCS activity and atherosclerosis development ENSG00000135218 ENSG00000167910 ENSG00000113161 ENSG00000198911 PMC8208232__F1 Cross-talk between lipid homeostasis and endoplasmic reticulum stress in neurodegeneration: insights for HIV-1 associated neurocognitive disorders (HAND) ENSG00000042832 ENSG00000144895 ENSG00000173599 PMC11546859__F12 Analysis of the pentose phosphate metabolic pathway PMC11546859__F11 Analysis of the glycolysis/gluconeogenesis metabolic pathway ENSG00000091140 PMC3421730__F6 The antiviral IFN response in infected THP-1 cells ENSG00000236637 ENSG00000127445 ENSG00000183735 ENSG00000088888 ENSG00000111537 ENSG00000187608 ENSG00000137275 ENSG00000177606 ENSG00000132478 ENSG00000131323 ENSG00000168040 ENSG00000175104 PMC9196867__F1 Current Concepts on Pathogenic Mechanisms and Histopathology in Cutaneous Lupus Erythematosus ENSG00000186810 ENSG00000183735 ENSG00000164430 ENSG00000172936 PMC4349428__F2 The relationship between genotypes and phenotypes of the nucleotide excision repair pathway and risk of SCCHN ENSG00000012061 ENSG00000136936 PMC8304822__F1 Targeting PI3K/AKT/mTOR Signaling Pathway in Breast Cancer ENSG00000011451 PMC9463785__F1 Weipiling decoction alleviates N-methyl-N-nitro-N′-nitrosoguanidine-induced gastric precancerous lesions via NFKB signalling pathway inhibition ENSG00000135218 ENSG00000169710 ENSG00000088256 ENSG00000171791 ENSG00000112715 ENSG00000164305 ENSG00000277571 ENSG00000117525 ENSG00000150991 ENSG00000110148 ENSG00000136997 ENSG00000276051 ENSG00000001626 ENSG00000121853 ENSG00000139687 ENSG00000171105 ENSG00000005339 ENSG00000197635 ENSG00000116044 ENSG00000173039 ENSG00000273686 ENSG00000140465 ENSG00000157005 ENSG00000073756 ENSG00000168610 ENSG00000108691 ENSG00000224320 ENSG00000177606 ENSG00000132646 ENSG00000005381 ENSG00000146648 ENSG00000127948 ENSG00000023839 PMC3279601__F1 The Immunologic Revolution: Photoimmunology ENSG00000116031 ENSG00000158473 ENSG00000137033 ENSG00000121966 PMC9463785__F3 Weipiling decoction alleviates N-methyl-N-nitro-N′-nitrosoguanidine-induced gastric precancerous lesions via NFKB signalling pathway inhibition ENSG00000143799 ENSG00000135218 ENSG00000291971 ENSG00000163739 ENSG00000130649 ENSG00000198793 ENSG00000168036 ENSG00000169710 ENSG00000088256 ENSG00000171791 ENSG00000112715 ENSG00000121879 ENSG00000124762 ENSG00000121966 ENSG00000150782 ENSG00000117525 ENSG00000110148 ENSG00000149968 ENSG00000136997 ENSG00000276051 ENSG00000123374 ENSG00000087842 ENSG00000001626 ENSG00000121853 ENSG00000108821 ENSG00000263238 ENSG00000087245 ENSG00000171105 ENSG00000005339 ENSG00000109320 ENSG00000131747 ENSG00000173039 ENSG00000140465 ENSG00000157005 ENSG00000007171 ENSG00000132170 ENSG00000108691 ENSG00000111537 ENSG00000177606 ENSG00000005381 ENSG00000096717 ENSG00000146648 ENSG00000116096 ENSG00000023839 PMC9491525__F6 Putative BvrR/BvrS TCS regulon in B. abortus upon entry into the host cell ENSG00000185129 PMC6913305__F4 Regulatory network of transcription factors in OA includes dark green quadrilateral module and light green rectangle module ENSG00000064490 ENSG00000253293 ENSG00000124496 ENSG00000122877 ENSG00000020633 ENSG00000168036 ENSG00000127528 ENSG00000136826 ENSG00000012048 ENSG00000157557 ENSG00000245848 ENSG00000127663 ENSG00000082175 ENSG00000066336 ENSG00000105991 ENSG00000175832 ENSG00000145741 ENSG00000176046 ENSG00000185591 ENSG00000291761 ENSG00000100219 ENSG00000139687 ENSG00000064835 ENSG00000133111 ENSG00000100811 ENSG00000143390 ENSG00000137273 ENSG00000109320 ENSG00000183072 ENSG00000078399 ENSG00000173039 ENSG00000162924 ENSG00000105698 ENSG00000168610 ENSG00000149311 ENSG00000128272 ENSG00000115415 ENSG00000177606 ENSG00000111653 ENSG00000198911 PMC5002303__F2 Insulin signaling pathway ENSG00000171105 ENSG00000002330 ENSG00000005882 ENSG00000150907 ENSG00000198793 ENSG00000026103 PMC3004338__F4 Ingenuity Pathway Analysis (IPA) of differentially expressed genes between 24 DSS and 56 uncomplicated dengue patients ENSG00000196136 ENSG00000196388 ENSG00000003436 ENSG00000173933 ENSG00000167074 ENSG00000169397 ENSG00000110876 PMC7728626__F3 C-Jun N‑terminal kinase (JNK) activation in obesity-induced diet: ENSG00000105550 PMC8763135__F3 Immune-targeted therapeutics and mechanisms of action investigated in major depressive disorder ENSG00000162711 ENSG00000150782 PMC4945937__F8 Metabonomics applied in exploring the antitumour mechanism of physapubenolide on hepatocellular carcinoma cells by targeting glycolysis through the Akt-p53 pathway ENSG00000078237 ENSG00000115419 PMC10526115__F3 Why Is Iron Deficiency/Anemia Linked to Alzheimer’s Disease and Its Comorbidities, and How Is It Prevented? ENSG00000117020 ENSG00000128272 ENSG00000169047 ENSG00000136003 ENSG00000112115 PMC5659989__F1 Overview of the role of adiponectin in the crosstalk between AT and the cardiovascular system for the regulation of cardiovascular redox state PMC2742468__F1 Metabolic cooperativity between oocytes and cumulus cells, and the role of oocyte-derived paracrine factors in promoting metabolism in cumulus cells ENSG00000160752 ENSG00000110921 ENSG00000074800 ENSG00000164404 ENSG00000067057 ENSG00000130385 ENSG00000104549 ENSG00000188338 PMC5529882__F3 Detailed molecular network of pathways of the cell cycle (Kyoto Encyclopedia of Genes and Genomes ID, has04110) ENSG00000145604 ENSG00000094804 ENSG00000108055 ENSG00000132646 ENSG00000136997 ENSG00000123374 ENSG00000164754 ENSG00000277273 PMC10813163__F1 Schematic illustration of leptin-induced signaling pathways ENSG00000198793 ENSG00000168610 PMC8613079__F1 Complement in metabolic disease: metaflammation and a two-edged sword ENSG00000166278 PMC11813047__F1 STAT3 signaling pathway ENSG00000291971 ENSG00000168610 PMC3749067__F1 Wnt/Beta-catenin signaling pathway ENSG00000134982 ENSG00000168036 PMC5621755__F2 AhRR with the canonical and non-canonical AhR pathways ENSG00000108702 ENSG00000104856 ENSG00000106546 PMC5621755__F1 Schematic illustration of the repression of the canonical AhR signaling pathway by AhRR ENSG00000106546 PMC10033548__F7 SFRP1 induces a stem cell phenotype in prostate cancer cells ENSG00000134982 ENSG00000168036 ENSG00000104332 PMC7522570__F9 Expression of orthologs annotated for the Kyoto Encyclopedia of Genes and Genomes (KEGG) tricarboxylic acid cycle (ko00020) pathway present in pleural ventral caudal sensory neuron (PVC) expression clusters with decreasing trend (P4 and P5) ENSG00000131473 ENSG00000073578 ENSG00000173599 ENSG00000105953 ENSG00000172340 ENSG00000124253 ENSG00000131828 ENSG00000091140 ENSG00000062485 PMC7522570__F8 Expression of orthologs annotated for the Kyoto Encyclopedia of Genes and Genomes (KEGG) glycolysis and gluconeogenesis (ko00010) pathway present in pleural ventral caudal sensory neuron (PVC) expression clusters with decreasing trend (P4 and P5) ENSG00000262785 ENSG00000074800 ENSG00000159322 ENSG00000226784 ENSG00000187758 ENSG00000124253 ENSG00000131828 ENSG00000091140 ENSG00000107789 PMC4753283__F1 The kynurenine pathway of tryptophan catabolism and markers of interferon-Gamma-mediated immune activation PMC7651821__F2 Tumor progression by E3 ligases and DUBs ENSG00000157764 ENSG00000134982 ENSG00000198793 ENSG00000169710 ENSG00000127191 ENSG00000117399 ENSG00000101557 ENSG00000145604 ENSG00000100387 ENSG00000113558 ENSG00000150907 ENSG00000083799 ENSG00000175104 ENSG00000198625 ENSG00000109670 PMC3894167__F1 Is Non-Homologous End-Joining Really an Inherently Error-Prone Process? ENSG00000143799 ENSG00000149311 PMC2930641__F2 MAPK Signaling Pathway ENSG00000087095 ENSG00000172680 ENSG00000130522 ENSG00000138798 ENSG00000130159 ENSG00000101224 ENSG00000127191 ENSG00000081189 ENSG00000170458 ENSG00000149269 ENSG00000175104 ENSG00000146648 ENSG00000196712 ENSG00000026103 PMC7185488__F3 Hypothesized Human Endogenous Retrovirus (HERV)-Mediated Activation Cascades Leading to the Pathogenesis of Multiple Sclerosis (MS) ENSG00000134982 ENSG00000136869 ENSG00000281857 PMC1868540__F1 Canonical Wnt Signaling Pathway ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3742224__F3 Structure of human cine-N-methyltransferase (GNMT) gene in connection with scheme of sarcosine genesis in biochemical pathway PMC7107779__F7 Diagram revealing the impact of p62 on the initiation and development of tumors in prostate tissues through the Keap1/Nrf2/ARE pathway ENSG00000181019 ENSG00000023909 ENSG00000079999 PMC1551980__F4 Ubiquitin Signaling in the NFKB Pathway ENSG00000167207 ENSG00000102871 ENSG00000172936 ENSG00000175104 ENSG00000127191 PMC1551980__F3 Ubiquitin Signaling in the NFKB Pathway ENSG00000172936 ENSG00000083799 ENSG00000175104 PMC2919275__F2 PD-1 Pathway in Tolerance and Autoimmunity ENSG00000198793 PMC2919275__F3 PD-1 Pathway in Tolerance and Autoimmunity ENSG00000134982 ENSG00000049768 PMC4402192__F2 Role of antagonists in Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000163914 PMC4402192__F1 Canonical and noncanonical Wnt signaling pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000163914 PMC5312537__F6 Changes in upper glycolysis, glycerolipid metabolism and pentose phosphate pathway during aging ENSG00000067057 ENSG00000159399 PMC5843704__F8 Proposed model for the role of DAPK1‐mediated Beclin‐1 phosphorylation and TTP‐mediated Bcl‐2 mRNA destabilization in autophagy leading to the suppression of inflammatory responses by gAcrp in macrophages ENSG00000159346 ENSG00000172936 ENSG00000175104 PMC1551980__F1 Ubiquitin Signaling in the NFKB Pathway ENSG00000104856 ENSG00000082512 ENSG00000162924 ENSG00000127191 PMC9035186__F3 Signaling cascades in the failing heart and emerging therapeutic strategies ENSG00000198576 ENSG00000168040 PMC9224119__F1 TLR/WNT: A Novel Relationship in Immunomodulation of Lung Cancer ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC8037234__F3 E2s participate in the DNA repair pathway ENSG00000155827 ENSG00000144554 ENSG00000077152 ENSG00000132646 ENSG00000112130 PMC10036296__F1 An Evolving Understanding of the Basis and Management of Vascular Complications of COVID-19: Where Do We Go From Here? ENSG00000110799 ENSG00000130234 ENSG00000132693 PMC12059369__F5 Key signaling pathways involved in the therapeutic mechanism of andrographolide (AD) in diabetic nephropathy (DN) ENSG00000087245 ENSG00000084093 ENSG00000142192 ENSG00000002330 ENSG00000183979 ENSG00000172936 ENSG00000007908 ENSG00000162692 ENSG00000168610 PMC3202988__F1 Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells ENSG00000147162 ENSG00000198408 PMC7984363__F2 HIF regulation and function on POMC ENSG00000134086 ENSG00000115138 ENSG00000166603 PMC12238214__F6 Hepatocyte nuclear factor 4-Alpha: a key regulator in liver carcinogenesis PMC12238214__F5 HNF4A Downregulation Drives Hepatocellular Carcinoma Proliferation and Genomic Instability: Downregulation of HNF4A promotes HCC progression through key molecular pathways PMC6029659__F6 H2S targets key host factors and viral steps to perturb replication of enveloped RNA viruses ENSG00000102871 ENSG00000185591 ENSG00000079999 PMC8020248__F2 Dysregulated MET activation, signaling pathway, and tumorigenic consequence ENSG00000124102 ENSG00000019991 ENSG00000168036 ENSG00000146648 ENSG00000140443 PMC6190278__F1 Heterologous effects of infant BCG vaccination: potential mechanisms of immunity ENSG00000170458 ENSG00000138798 ENSG00000198793 ENSG00000136869 PMC5386972__F2 MYC promotes anabolic metabolism ENSG00000136997 ENSG00000159399 PMC8037234__F5 E2s participate in the NFKB pathway ENSG00000104856 ENSG00000244687 ENSG00000102871 ENSG00000186716 ENSG00000082512 ENSG00000111321 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000127191 PMC5683310__F2 Molecular pathways regulated by ZNFs in physiological conditions ENSG00000122180 ENSG00000141579 ENSG00000198336 ENSG00000133710 ENSG00000237165 ENSG00000168036 ENSG00000081277 ENSG00000175029 ENSG00000143631 ENSG00000136826 ENSG00000133055 ENSG00000132170 ENSG00000101773 ENSG00000004487 ENSG00000118898 ENSG00000051128 ENSG00000089902 ENSG00000274137 PMC6664754__F2 Proposed model of the Lgr5-mediated stimulation of cancer growth through activation of the Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC8496198__F7 PI3KG/AKT Signaling in High Molecular Weight Hyaluronan (HMWH)-Induced Anti-Hyperalgesia and Reversal of Nociceptor Sensitization ENSG00000198793 ENSG00000026508 PMC9322180__F1 Genetics in Familial Intrahepatic Cholestasis: Clinical Patterns and Development of Liver and Biliary Cancers: A Review of the Literature ENSG00000160867 ENSG00000148400 ENSG00000167910 ENSG00000173599 ENSG00000001626 PMC6738120__F1 BRAF pathway ENSG00000157764 ENSG00000198793 ENSG00000146648 PMC5549800__F6 Vascular Endothelial Growth Factor A and Leptin Expression Associated with Ectopic Proliferation and Retinal Dysplasia in Zebrafish Optic Pathway Tumors ENSG00000168209 ENSG00000163435 ENSG00000173599 PMC6406361__F7 Main steps of arginine metabolism ENSG00000036473 PMC6943877__F1 Pattern recognition receptors and inflammasome sensing mechanism during influenza A virus (IAV) infection ENSG00000162711 ENSG00000213928 ENSG00000088888 ENSG00000115415 ENSG00000125538 ENSG00000172936 ENSG00000164342 PMC9479306__F1 Non-coding RNAs and epithelial mesenchymal transition in cancer: molecular mechanisms and clinical implications ENSG00000169554 ENSG00000070831 ENSG00000134982 ENSG00000170558 ENSG00000168036 ENSG00000113360 PMC7104260__F1 Internal cues and the mating-pheromone-response pathway converge on the activation of Cdc42 ENSG00000070831 ENSG00000173976 ENSG00000177084 ENSG00000197601 PMC3429544__F8 Autophagy is induced through the ROS-TP53-DRAM1 pathway in response to mitochondrial protein synthesis inhibition ENSG00000132591 ENSG00000136048 PMC2989726__F5 CFTR Chloride Channel in the Apical Compartments: Spatiotemporal Coupling to its Interacting Partners ENSG00000065054 ENSG00000198670 ENSG00000001626 PMC6406361__F1 TNF-related apoptosis-inducing ligand (TRAIL)-induced signaling pathways ENSG00000132906 ENSG00000137275 ENSG00000157625 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000164305 ENSG00000285379 PMC6743792__F7 Executable pathway analysis using ensemble discrete-state modeling for large-scale data ENSG00000140992 ENSG00000112576 ENSG00000110330 ENSG00000134215 ENSG00000100852 ENSG00000091409 ENSG00000171791 ENSG00000100485 ENSG00000138964 ENSG00000213949 ENSG00000107263 ENSG00000140443 ENSG00000023445 ENSG00000124102 ENSG00000077157 ENSG00000145949 ENSG00000002330 ENSG00000070831 ENSG00000050748 ENSG00000115904 ENSG00000168036 ENSG00000150093 ENSG00000105647 ENSG00000169032 ENSG00000099942 ENSG00000118971 ENSG00000121879 ENSG00000141968 ENSG00000089159 ENSG00000160007 ENSG00000169231 ENSG00000149269 ENSG00000166501 ENSG00000130402 ENSG00000139626 ENSG00000136068 ENSG00000157764 ENSG00000118680 ENSG00000186111 ENSG00000067900 ENSG00000291420 ENSG00000186298 ENSG00000160691 ENSG00000117020 ENSG00000010810 ENSG00000177606 ENSG00000072110 ENSG00000154059 ENSG00000137076 ENSG00000171608 ENSG00000115232 ENSG00000101608 PMC7937231__F8 Bacterial invasion of epithelial cells pathway (KEGG ID:hsa05100) in the CoPS vs ENSG00000110395 ENSG00000106299 ENSG00000122705 PMC5751331__F1 Lysophospholipid-mediated PPARG signaling ENSG00000129219 ENSG00000173599 ENSG00000198670 ENSG00000047936 PMC2782452__F1 Different views of the Akt pathway/network ENSG00000002330 ENSG00000198793 ENSG00000135605 PMC7540110__F1 Cell cycle regulation through cyclin E ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC7033644__F2 EV trafficking between leukemia and stromal cells reduces sensitivity to chemotherapeutics ENSG00000163464 ENSG00000178860 ENSG00000173599 PMC2644070__F2 Homologies between mammalian and insect immune defense pathways ENSG00000102871 ENSG00000056558 ENSG00000168040 ENSG00000175104 ENSG00000127191 PMC5290198__F7 BRD4 regulates breast cancer dissemination through Jagged1/Notch1 signaling ENSG00000141867 ENSG00000148400 PMC3616609__F2 The multi-step pathway of CENP-A-containing centromeric chromatin replication utilizing sequential, temporally separated steps across the mammalian cell cycle ENSG00000114346 ENSG00000070831 ENSG00000134982 ENSG00000123485 ENSG00000123374 PMC7146499__F2 Dehydration alters hippocampal transcriptional networks ENSG00000149084 ENSG00000181788 ENSG00000169241 ENSG00000130396 ENSG00000142178 ENSG00000167470 ENSG00000137094 ENSG00000291971 ENSG00000159388 ENSG00000112715 ENSG00000179588 ENSG00000291507 ENSG00000068976 ENSG00000197971 ENSG00000197283 ENSG00000132326 ENSG00000120251 ENSG00000132535 ENSG00000144655 ENSG00000147044 ENSG00000160145 ENSG00000152495 ENSG00000168724 ENSG00000189056 ENSG00000179915 ENSG00000150551 ENSG00000100151 ENSG00000001630 ENSG00000150672 ENSG00000198576 ENSG00000137575 ENSG00000184216 PMC8316210__F8 Latent Membrane Protein 1 Promotes Tumorigenesis Through Upregulation of PGC1B Signaling Pathway ENSG00000106459 PMC3635124__F1 Shh signalling pathway1 ENSG00000064309 ENSG00000187240 ENSG00000101052 ENSG00000121067 ENSG00000150459 ENSG00000114446 ENSG00000138002 ENSG00000180447 ENSG00000168014 ENSG00000106571 ENSG00000164161 ENSG00000164066 ENSG00000144857 ENSG00000166813 ENSG00000010361 ENSG00000154309 ENSG00000164690 ENSG00000128602 PMC2859499__F7 TAK1·TAB2·NLK complex negatively regulating canonical Wnt pathway ENSG00000087095 ENSG00000138795 PMC12133520__F2 Thymus cell development and regulation mechanism ENSG00000165030 ENSG00000020633 ENSG00000107485 PMC5666637__F5 Transforming growth factor B (TGFB) and bone morphogenetic protein (BMP) signaling in bone homeostasis ENSG00000087245 ENSG00000167941 ENSG00000100985 PMC5666637__F3 Summary of the bone morphogenetic protein (BMP) and growth and differentiation factor (GDF) signaling pathway and mutations causing connective tissue and skeletal disorders ENSG00000170365 ENSG00000281324 ENSG00000162337 ENSG00000167941 PMC3276354__F1 Canonical Wnt (Wnt/Beta-catenin) signaling pathway (adapted from Ref ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000198793 ENSG00000168036 ENSG00000167074 PMC4355017__F6 Drugging the undruggable Ras: mission possible? ENSG00000065833 ENSG00000197713 ENSG00000074800 ENSG00000153574 PMC6085474__F7 Regulatory pathways of ERBB2+ GC ENSG00000136997 ENSG00000158458 PMC6890986__F1 Apoptosis and necrosis pathways ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC6890986__F3 Mitochondrial apoptosis pathway ENSG00000100290 ENSG00000002330 ENSG00000135116 ENSG00000104081 PMC6890986__F7 Pyroptosis ENSG00000278718 ENSG00000162711 ENSG00000088888 PMC12070581__F9 Map of specific pathways under imazapyr acid stress ENSG00000105486 ENSG00000132646 ENSG00000198168 PMC7072176__F3 Viral miRNAs affect the pathways involved in the carcinogenesis of host cells ENSG00000159216 ENSG00000239282 ENSG00000164305 PMC6447583__F8 Notch signaling in astrocytes mediates their morphological response to an inflammatory challenge ENSG00000273529 PMC6491837__F2 Positive and negative feedback signals for neuronal polarization ENSG00000070831 ENSG00000156299 ENSG00000149269 ENSG00000170558 ENSG00000163914 ENSG00000133961 ENSG00000075213 PMC6604281__F1 Fanconi anemia curated map, based in the KEGG FA pathway ENSG00000164053 ENSG00000083093 ENSG00000187790 ENSG00000168411 ENSG00000139618 ENSG00000131944 ENSG00000175054 ENSG00000144554 ENSG00000108384 ENSG00000051180 ENSG00000009413 ENSG00000122008 ENSG00000122512 PMC3701722__F1 Autophagy and endocrine resistance in breast cancer ENSG00000177169 ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC8490548__F2 MTHFR (methylenetetrahydrofolate reductase: EC 1.5.1.20) SNPs (single-nucleotide polymorphisms) and homocysteine in patients referred for investigation of fertility ENSG00000228716 PMC11939858__F1 Influence of RANKL, sclerostin, and DKK1 on glucose metabolism and the corresponding signaling cascade ENSG00000281324 ENSG00000162337 ENSG00000197635 ENSG00000134982 ENSG00000163739 ENSG00000198793 ENSG00000168036 ENSG00000131323 PMC5871764__F2 Notch pathway ENSG00000005339 ENSG00000138613 ENSG00000163840 ENSG00000196591 ENSG00000273529 ENSG00000133961 ENSG00000114315 ENSG00000175029 ENSG00000106003 ENSG00000114166 PMC5871764__F1 Notch pathway ENSG00000004975 ENSG00000005339 ENSG00000138613 ENSG00000163840 ENSG00000196591 ENSG00000100060 ENSG00000273529 ENSG00000133961 ENSG00000114315 ENSG00000175029 ENSG00000114166 ENSG00000091073 PMC3871277__F1 Panitumumab and epidermal growth factor receptor (EGFR) signaling pathway ENSG00000169291 ENSG00000198793 ENSG00000146648 PMC6893313__F8 Representative model of the MMP-2 and MMP-9 secretion induced by leptin in a cultured model for breast cancer ENSG00000291971 ENSG00000168610 PMC8197283__F2 WNT4 Balances Development vs Disease in Gynecologic Tissues and Women’s Health ENSG00000162552 ENSG00000253293 ENSG00000143768 ENSG00000150907 ENSG00000146678 ENSG00000168036 PMC4518644__F5 Example of using “Effect on Metabolism” tool to see the overall proteome result mapped on carbon fixation metabolism ENSG00000291355 ENSG00000172005 PMC4518644__F4 Example of using “Inter-pathways” tool to query interactions between two pathways (left─syn00710: Carbon fixation; right─syn00480: glutathione metabolism) ENSG00000074266 ENSG00000002549 PMC6801436__F2 JAK1-TYK2 heterodimer signaling pathway ENSG00000111537 ENSG00000105397 ENSG00000115415 PMC9358975__F1 Correlation Between MicroRNAs and Diabetic Retinopathy ENSG00000128272 ENSG00000154485 ENSG00000148400 ENSG00000179091 PMC7311964__F1 Wnt pathway drug targets ENSG00000134982 ENSG00000168036 ENSG00000117899 ENSG00000104332 PMC9185696__F1 Interplay of retinol binding protein 4 with obesity and associated chronic alterations ENSG00000138207 ENSG00000086991 ENSG00000136869 ENSG00000069956 ENSG00000162692 ENSG00000175104 ENSG00000214253 PMC8402498__F9 Escherichia coli Alpha-Hemolysin HlyA Induces Host Cell Polarity Changes, Epithelial Barrier Dysfunction and Cell Detachment in Human Colon Carcinoma Caco-2 Cell Model via PTEN-Dependent Dysregulation of Cell Junctions ENSG00000136997 PMC3552883__F8 Autophagy-dependent EIF2AK3 activation compromises ursolic acid-induced apoptosis through upregulation of MCL1 in MCF-7 human breast cancer cells ENSG00000057663 PMC3653120__F4 Effect of physical activity and obesity on the growth and development of colon carcinogenesis ENSG00000132646 ENSG00000136997 ENSG00000168036 PMC3653120__F3 Effect of cigarette smoke on the etiology of colon carcinogenesis ENSG00000157764 ENSG00000146648 PMC1681473__F1B (B) The bow-tie architecture also exists at the signal transduction level ENSG00000138378 ENSG00000226275 ENSG00000115415 ENSG00000107485 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000164342 PMC4684962__F5 Methylome-wide Sequencing Detects DNA Hypermethylation Distinguishing Indolent from Aggressive Prostate Cancer ENSG00000109452 ENSG00000104221 ENSG00000065618 ENSG00000261857 ENSG00000123064 ENSG00000031003 ENSG00000116754 ENSG00000198785 ENSG00000185942 ENSG00000160710 ENSG00000127511 ENSG00000164327 ENSG00000100246 ENSG00000105085 ENSG00000151693 ENSG00000074201 ENSG00000148606 ENSG00000128849 ENSG00000172037 ENSG00000198569 ENSG00000084628 ENSG00000183943 ENSG00000110717 ENSG00000104973 ENSG00000135932 ENSG00000008300 ENSG00000014138 ENSG00000163017 ENSG00000099365 ENSG00000180008 ENSG00000140464 ENSG00000179348 ENSG00000170608 ENSG00000165934 ENSG00000182158 ENSG00000125107 ENSG00000063244 ENSG00000108510 ENSG00000140807 ENSG00000197461 ENSG00000147642 ENSG00000080802 ENSG00000101161 ENSG00000291470 ENSG00000187554 ENSG00000070371 ENSG00000143126 ENSG00000140285 ENSG00000146122 ENSG00000130309 ENSG00000133961 ENSG00000136448 ENSG00000127616 ENSG00000167553 ENSG00000175221 ENSG00000136425 ENSG00000175220 ENSG00000123066 ENSG00000175550 ENSG00000135966 ENSG00000105647 ENSG00000104332 ENSG00000143858 ENSG00000127129 ENSG00000147123 ENSG00000038382 ENSG00000117713 ENSG00000106683 ENSG00000162572 ENSG00000011422 ENSG00000099995 ENSG00000115457 ENSG00000175832 ENSG00000088247 ENSG00000132383 ENSG00000124181 ENSG00000162188 ENSG00000136068 ENSG00000116044 ENSG00000106477 ENSG00000173011 ENSG00000007312 ENSG00000105402 ENSG00000177565 ENSG00000103942 ENSG00000101972 ENSG00000117020 ENSG00000111319 ENSG00000137074 ENSG00000243646 ENSG00000142089 ENSG00000099795 ENSG00000161202 ENSG00000136940 ENSG00000141367 ENSG00000087274 ENSG00000176102 ENSG00000011600 ENSG00000118007 ENSG00000160075 ENSG00000275700 ENSG00000102606 ENSG00000185436 ENSG00000072274 ENSG00000141068 ENSG00000112118 ENSG00000160783 ENSG00000100385 ENSG00000170365 ENSG00000239732 ENSG00000291507 ENSG00000066336 ENSG00000172216 ENSG00000128159 ENSG00000083444 ENSG00000106070 ENSG00000123810 ENSG00000175766 ENSG00000220205 ENSG00000276111 ENSG00000076641 ENSG00000164344 ENSG00000184304 ENSG00000172201 ENSG00000166341 ENSG00000185022 ENSG00000160145 ENSG00000105438 ENSG00000169783 ENSG00000105568 ENSG00000112293 ENSG00000183785 ENSG00000111145 ENSG00000183648 ENSG00000115884 ENSG00000242247 ENSG00000130052 ENSG00000134574 ENSG00000173372 ENSG00000082805 ENSG00000116584 ENSG00000151617 ENSG00000213672 ENSG00000136936 ENSG00000100196 ENSG00000139567 ENSG00000157193 ENSG00000198793 ENSG00000087008 ENSG00000123104 ENSG00000124875 ENSG00000110801 ENSG00000064300 ENSG00000197702 ENSG00000175216 ENSG00000104368 ENSG00000184381 ENSG00000160584 ENSG00000078747 ENSG00000196235 ENSG00000168310 ENSG00000072422 ENSG00000213024 ENSG00000253729 ENSG00000089597 ENSG00000100811 ENSG00000163399 ENSG00000027075 ENSG00000104365 ENSG00000172380 ENSG00000140262 ENSG00000109320 ENSG00000162924 ENSG00000143228 ENSG00000092199 ENSG00000139880 ENSG00000079999 ENSG00000160691 ENSG00000172183 ENSG00000136099 ENSG00000100280 ENSG00000148660 ENSG00000101849 ENSG00000008838 ENSG00000101440 ENSG00000115020 ENSG00000143322 ENSG00000110713 ENSG00000204217 ENSG00000114739 PMC9338328__F2 Radiotherapy combined with immunotherapy: the dawn of cancer treatment ENSG00000049768 ENSG00000168610 PMC9338328__F5 Radiotherapy combined with immunotherapy: the dawn of cancer treatment ENSG00000108691 ENSG00000107562 ENSG00000121807 ENSG00000168610 ENSG00000121966 PMC9338328__F6 Radiotherapy combined with immunotherapy: the dawn of cancer treatment ENSG00000183735 ENSG00000108691 ENSG00000164430 ENSG00000121807 ENSG00000168610 PMC6128898__F9 Expression patterns of T ENSG00000197429 ENSG00000104549 PMC7814595__F3 Different T cell subsets infiltrate the injured brain ENSG00000109321 ENSG00000138755 PMC5536086__F1 Proposed model for UCP2-SIRT3 (uncoupling protein 2-sirtuin 3) signaling pathway on cerebral ischemia–reperfusion injury ENSG00000047936 ENSG00000175567 ENSG00000142082 PMC8255631__F2 Autoimmunity as an Etiological Factor of Cancer: The Transformative Potential of Chronic Type 2 Inflammation ENSG00000134982 ENSG00000163599 ENSG00000113520 PMC7814595__F2 Functions of T cell subsets in the acute and chronic phases after ischaemic stroke ENSG00000109321 ENSG00000106546 PMC7531772__F5 Genome of the Softshell Clam Mya arenaria and the Evolution of Apoptosis ENSG00000132906 ENSG00000110711 ENSG00000002330 ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000115317 ENSG00000149311 ENSG00000291983 ENSG00000128272 ENSG00000144895 ENSG00000135116 ENSG00000064012 ENSG00000026103 ENSG00000084774 PMC5666637__F2 Summary of the transforming growth factor B (TGFB) signaling pathway and mutations causing connective tissue disorders ENSG00000157933 PMC5312359__F7 MicroRNA 10b promotes abnormal expression of the proto-oncogene c-Jun in metastatic breast cancer cells ENSG00000128710 ENSG00000196712 PMC3924561__F1 Functional Relevance of Biased Signaling at the Angiotensin II Type 1 Receptor ENSG00000002330 ENSG00000113070 ENSG00000146648 PMC7017938__F1 Opioid activity in cancer ENSG00000087245 ENSG00000163914 ENSG00000100985 ENSG00000168610 ENSG00000146648 PMC6541264__F2 Molecular mechanisms involved in drug-induced liver injury caused by urate-lowering Chinese herbs ENSG00000181163 ENSG00000171444 ENSG00000291971 ENSG00000095015 ENSG00000165280 ENSG00000170606 ENSG00000168036 ENSG00000087586 ENSG00000073111 ENSG00000012048 ENSG00000168283 ENSG00000134086 ENSG00000079246 ENSG00000150991 ENSG00000198742 ENSG00000263528 ENSG00000123374 ENSG00000001626 ENSG00000253729 ENSG00000166167 ENSG00000187531 ENSG00000142192 ENSG00000005339 ENSG00000170027 ENSG00000269335 ENSG00000173039 ENSG00000143933 ENSG00000173226 ENSG00000105568 ENSG00000127191 ENSG00000072803 ENSG00000086758 ENSG00000168610 ENSG00000160691 ENSG00000069869 ENSG00000141480 ENSG00000121481 ENSG00000177606 ENSG00000132646 ENSG00000147601 ENSG00000074266 ENSG00000162692 ENSG00000115232 ENSG00000146648 ENSG00000141367 PMC5700130__F4 Representative terpenoid biosynthesis pathway with cognate heat maps for transcript levels of genes from transcriptome data with substrates and products, colored arrows connect substrates to their corresponding products ENSG00000067064 ENSG00000152904 ENSG00000197429 ENSG00000148377 PMC8584528__F1 Model Identifies Genetic Predisposition of Alzheimer’s Disease as Key Decider in Cell Susceptibility to Stress ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC12246121__F11 Translation regulations in PRRs ENSG00000116001 ENSG00000163435 ENSG00000166523 ENSG00000288145 ENSG00000198793 ENSG00000167658 ENSG00000127666 PMC3343135__F2 Differential expression of mRNA and proteins encoding factors in the Notch signaling pathway ENSG00000133961 PMC5992987__F4 Putative signaling pathway composed of FOXM1, MYC and miR-34a ENSG00000143799 ENSG00000115163 ENSG00000119403 ENSG00000112118 ENSG00000111641 ENSG00000136231 ENSG00000145604 ENSG00000012048 ENSG00000138778 ENSG00000117650 ENSG00000132646 ENSG00000112984 ENSG00000136997 ENSG00000171848 ENSG00000146410 ENSG00000282899 ENSG00000175305 ENSG00000176619 PMC12246121__F14 PRR in ageing ENSG00000239732 ENSG00000164430 ENSG00000187554 ENSG00000140968 ENSG00000189403 ENSG00000136869 PMC9106063__F7 ST2825, a Small Molecule Inhibitor of MyD88, Suppresses NFKB Activation and the ROS/NLRP3/Cleaved Caspase-1 Signaling Pathway to Attenuate Lipopolysaccharide-Stimulated Neuroinflammation ENSG00000162711 ENSG00000170458 ENSG00000125538 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC7573235__F4 Signaling pathways activated by AKT1(E17K) ENSG00000169047 ENSG00000137193 ENSG00000175104 ENSG00000292210 PMC7573235__F3 Signaling pathways activated by AKT ENSG00000169047 ENSG00000137193 ENSG00000175104 ENSG00000292210 PMC8391653__F2 Extra- and Intra-Cellular Mechanisms of Hepatic Stellate Cell Activation ENSG00000135547 ENSG00000281324 ENSG00000196839 ENSG00000163914 ENSG00000291748 ENSG00000168036 ENSG00000108821 ENSG00000114315 ENSG00000128602 PMC1783691__F1 Differential Roles of Costimulatory Signaling Pathways in Type 1 Diabetes Mellitus ENSG00000134982 PMC6338529__F1 VGF/BDNF/TrkB autoregulatory feedback loop stimulates synaptic plasticity changes in response to rapid-acting antidepressant treatment ENSG00000165119 ENSG00000284161 ENSG00000128564 ENSG00000123908 PMC4172882__F1 (Rspo)s in canonical Wnt signaling pathway and the general architecture of (Rspo)s ENSG00000168036 ENSG00000167074 ENSG00000117322 PMC2826212__F2 An intricate gene regulatory network controls OL differentiation ENSG00000100811 ENSG00000184221 ENSG00000196591 ENSG00000205927 ENSG00000273529 ENSG00000100146 ENSG00000172201 PMC3646863__F4 Prognostic signature of G₂ checkpoint function in melanoma cell lines ENSG00000206560 ENSG00000157404 ENSG00000134982 ENSG00000103035 ENSG00000173482 ENSG00000129514 ENSG00000101224 ENSG00000135905 ENSG00000149311 ENSG00000175054 ENSG00000136169 ENSG00000137770 ENSG00000102878 ENSG00000128791 ENSG00000177606 ENSG00000198554 ENSG00000146122 ENSG00000166793 ENSG00000112029 ENSG00000146263 ENSG00000114166 PMC9016174__F1 Endometriosis-Associated Angiogenesis and Anti-angiogenic Therapy for Endometriosis ENSG00000134982 ENSG00000168036 PMC6245608__F3 Physiological regulation of autophagy in the heart ENSG00000177169 ENSG00000117525 ENSG00000150907 ENSG00000169047 ENSG00000112561 PMC3988467__F1 Amino acid signalling upstream of mTOR ENSG00000155792 ENSG00000167965 PMC8576330__F6 Involvement of the TGFB Signaling Pathway in the Development of YAP-Driven Osteosarcoma Lung Metastasis ENSG00000087245 ENSG00000136535 ENSG00000288335 ENSG00000100985 PMC6309606__F6 RAS/ERK, PI3K/AKT, WNT and Beta-catenin signaling pathways are involved in different stages of brain development and are commonly disrupted in ASD ENSG00000168036 PMC2826040__F5 miR-223 is implicated in the CREB signaling pathway ENSG00000125734 ENSG00000140443 PMC2826040__F4 miR-200a is implicated in the type I interferon signaling pathway ENSG00000138378 ENSG00000142166 PMC10526530__F2 What General Neurologists Should Know about Autoinflammatory Syndromes? ENSG00000162711 ENSG00000150782 ENSG00000110921 ENSG00000140368 ENSG00000164430 ENSG00000167207 ENSG00000154124 ENSG00000102172 PMC6338642__F7 BMP4-mediated anti-cancer effects in ER+ breast cancer ENSG00000170365 ENSG00000135446 ENSG00000105810 PMC8851529__F5 Alleles of AGT and HIF1A gene affect the risk of hypertension in plateau residents ENSG00000134086 ENSG00000138798 ENSG00000198793 ENSG00000072274 ENSG00000136869 ENSG00000168610 PMC5067143__F2 (Opposite and overleaf) Visualizing drug action ENSG00000115415 ENSG00000138798 ENSG00000146648 PMC5647276__F2 Daily and annual timing share neurobiological and molecular pathways ENSG00000158161 ENSG00000108924 ENSG00000167074 PMC10874285__F2 Interplay between HCV-induced autophagy and host innate immune response ENSG00000183735 ENSG00000164430 ENSG00000175104 PMC11707604__F3 Signal transduction via interleukin (IL)-4R complexes and mechanism of action of dupilumab ENSG00000105397 ENSG00000105639 PMC8851529__F2 Alleles of AGT and HIF1A gene affect the risk of hypertension in plateau residents ENSG00000064601 ENSG00000096395 ENSG00000100448 ENSG00000196549 ENSG00000130234 ENSG00000143839 ENSG00000172938 ENSG00000163751 ENSG00000137509 PMC10874285__F1 HCV inhibits the innate immune response ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000172936 ENSG00000175104 ENSG00000142166 PMC11707604__F1 Severe asthma immunopathogenesis in type 2 (T2)-high asthma and the specific targets of biologic therapies ENSG00000137033 ENSG00000145777 ENSG00000166090 PMC7274521__F6 Schematic description of resveratrol-mediated suppression of inflammation in IL-1Beta-induced SW1353 cells ENSG00000172936 ENSG00000136869 PMC7267026__F3 Positive and negative regulation of MAVS activity antiviral immunity ENSG00000087095 ENSG00000132109 ENSG00000147162 ENSG00000164164 ENSG00000162191 ENSG00000127191 ENSG00000185104 ENSG00000088888 ENSG00000198742 ENSG00000082512 ENSG00000179873 ENSG00000131323 ENSG00000175104 ENSG00000100304 PMC7267026__F2 RLR signaling pathways ENSG00000088888 ENSG00000082512 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000276561 PMC9048811__F2 Epigenetic mechanisms involved in mitochondrial dysfunction: Implication for Parkinson’s disease ENSG00000158828 ENSG00000142082 ENSG00000106459 PMC3689575__F1 Modeling the genetic basis for human sleep disorders in Drosophila ENSG00000170965 ENSG00000143815 ENSG00000006451 ENSG00000162924 PMC5347907__F3 Functional long noncoding RNAs (lncRNAs) in inflammatory pathways ENSG00000136869 ENSG00000197451 ENSG00000164342 PMC8281237__F1 Amino Acid Metabolic Vulnerabilities in Acute and Chronic Myeloid Leukemias ENSG00000284320 ENSG00000092621 ENSG00000060982 ENSG00000171759 ENSG00000135069 ENSG00000100033 ENSG00000146733 ENSG00000105552 ENSG00000070669 ENSG00000116761 ENSG00000115419 PMC9130726__F1 Molecular signaling pathways, pathophysiological features in various organs, and treatment strategies in SARS-CoV2 infection ENSG00000150782 ENSG00000125538 PMC8076548__F8 Baricitinib Ameliorates Experimental Autoimmune Encephalomyelitis by Modulating the Janus Kinase/Signal Transducer and Activator of Transcription Signaling Pathway ENSG00000138378 ENSG00000115415 ENSG00000168610 PMC6997398__F7 Pathological biological network construction of high calorie diet combined with pneumonia ENSG00000038382 ENSG00000108691 ENSG00000107562 ENSG00000197746 ENSG00000157017 ENSG00000096717 ENSG00000132693 ENSG00000275031 PMC4444189__F6 MicroRNAs Regulate Cellular ATP Levels by Targeting Mitochondrial Energy Metabolism Genes during C2C12 Myoblast Differentiation ENSG00000156885 ENSG00000099795 PMC6997227__F2 PI3K/PIP3 signaling activates Akt signaling via Akt/PDK-1 activation, which results in the downregulation of apoptosis ENSG00000169047 PMC6429226__F5 Apoptosis can be modulated by the activity of polyphenols in prostate cancer ENSG00000039537 ENSG00000100290 ENSG00000113600 ENSG00000002330 ENSG00000166278 ENSG00000120868 ENSG00000168040 ENSG00000104081 ENSG00000026103 PMC6429226__F3 The effects of polyphenols on signaling pathways in prostate cancer ENSG00000019991 ENSG00000291971 ENSG00000134982 ENSG00000138798 ENSG00000168036 PMC8998814__F4 Metastasis and MAPK Pathways ENSG00000070831 ENSG00000146648 PMC8998814__F3 Metastasis and MAPK Pathways ENSG00000176692 ENSG00000136535 ENSG00000070831 ENSG00000138798 ENSG00000198793 ENSG00000163914 ENSG00000175104 ENSG00000146648 PMC2818318__F4 Regulation of Cell Cycle and RNA Transcription Genes Identified by Microarray Analysis of PC-3 Human Prostate Cancer Cells Treated with Luteolin ENSG00000112576 ENSG00000145386 ENSG00000118971 ENSG00000166851 ENSG00000134480 ENSG00000137558 ENSG00000145604 ENSG00000094804 ENSG00000198176 ENSG00000134057 ENSG00000135446 ENSG00000132646 ENSG00000123374 ENSG00000105810 ENSG00000147082 ENSG00000139687 ENSG00000080839 ENSG00000175305 PMC8998814__F5 Metastasis and MAPK Pathways ENSG00000143842 ENSG00000124766 ENSG00000077782 ENSG00000123268 PMC8211510__F1 Huang-Pu-Tong-Qiao Formula Ameliorates the Hippocampus Apoptosis in Diabetic Cognitive Dysfunction Mice by Activating CREB/BDNF/TrkB Signaling Pathway ENSG00000161634 ENSG00000141086 PMC5905170__F1 Summary of the workflow followed in the present study PMC9263770__F9 Yinzhihuang oral liquid protects against non-alcoholic steatohepatitis via modulation of the gut-liver axis in mice ENSG00000125538 PMC8909699__F2 Advance of SOX Transcription Factors in Hepatocellular Carcinoma: From Role, Tumor Immune Relevance to Targeted Therapy ENSG00000164379 ENSG00000107562 ENSG00000177732 ENSG00000176887 ENSG00000198793 ENSG00000143842 ENSG00000124766 ENSG00000168036 ENSG00000176476 ENSG00000118777 ENSG00000110693 ENSG00000164736 ENSG00000125398 ENSG00000160867 ENSG00000005513 ENSG00000285438 ENSG00000037280 ENSG00000083799 ENSG00000137440 ENSG00000155760 ENSG00000203883 ENSG00000039600 PMC5024698__F8 Mechanism for HKa-induced endothelial apoptosis and inhibition of angiogenesis ENSG00000076641 PMC4580722__F2 Regulation of autophagy by amino acids ENSG00000177169 ENSG00000110497 ENSG00000123395 ENSG00000011566 ENSG00000198382 ENSG00000002330 ENSG00000126775 ENSG00000155792 ENSG00000112561 ENSG00000102104 ENSG00000151151 PMC4580722__F1 Autophagic machinery ENSG00000169228 ENSG00000177169 ENSG00000110497 ENSG00000123395 ENSG00000126775 ENSG00000196455 ENSG00000005893 ENSG00000070540 ENSG00000157954 PMC3340168__F13 Apoptotic and necrotic targets modulate viability of epithelial responder cells by eliciting multiple recognition-dependent signaling pathways ENSG00000002330 ENSG00000168036 PMC7848376__F6 A, On the left, the Neurotrophin signaling pathway (modified from KEGG hsa04722), showing genes targeted by miRNAs (n = 15) involved in its modulation ENSG00000002330 PMC4032270__F3 Oak Root Response to Ectomycorrhizal Symbiosis Establishment: RNA-Seq Derived Transcript Identification and Expression Profiling ENSG00000180210 ENSG00000062485 PMC7848376__F5 A, On the left, HIF‐1 signaling pathway (modified from KEGG hsa04066), showing genes targeted by miRNAs (n = 16) involved in its modulation ENSG00000002330 ENSG00000168040 PMC3577904__F3 Gene Expression Analyses Implicate an Alternative Splicing Program in Regulating Contractile Gene Expression and Serum Response Factor Activity in Mice ENSG00000159200 ENSG00000171476 ENSG00000143318 ENSG00000022267 ENSG00000120937 ENSG00000143632 PMC5363613__F6 Integrin A2B1 inhibits MST1 kinase phosphorylation and activates Yes-associated protein oncogenic signaling in hepatocellular carcinoma ENSG00000167601 PMC7787797__F8 PTP1B in IFN-Gamma-induced neuroinflammation and 6-OHDA-induced neuronal death ENSG00000120690 PMC8235304__F1 Opportunities for Ferroptosis in Cancer Therapy ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000197429 ENSG00000113161 ENSG00000023909 PMC11009036__F1 Nonsense-mediated RNA decay pathway ENSG00000162385 ENSG00000198952 ENSG00000151461 ENSG00000070366 ENSG00000125351 ENSG00000157106 PMC8844686__F6 Transcriptome analysis of inseminated sperm storage tubules throughout the duration of fertility in the domestic turkey, Meleagris gallopavo ENSG00000164171 ENSG00000112715 ENSG00000116906 ENSG00000276561 ENSG00000133216 ENSG00000159167 ENSG00000134321 ENSG00000177409 ENSG00000117226 ENSG00000178538 ENSG00000133106 ENSG00000082175 ENSG00000284838 ENSG00000134326 ENSG00000123609 ENSG00000135114 ENSG00000184371 ENSG00000142089 ENSG00000188820 ENSG00000115232 ENSG00000164342 PMC1992444__F3 Interaction map of the Notch signaling pathway ENSG00000111537 ENSG00000179111 ENSG00000188095 ENSG00000114315 ENSG00000106003 PMC3373577__F4 Increased Levels of BAFF and APRIL Related to Human Active Pulmonary Tuberculosis ENSG00000140564 ENSG00000100906 ENSG00000164761 ENSG00000173039 ENSG00000162924 ENSG00000158869 ENSG00000273936 ENSG00000132693 ENSG00000164305 ENSG00000040608 ENSG00000111537 ENSG00000077150 ENSG00000063660 ENSG00000102245 ENSG00000136997 ENSG00000131323 ENSG00000026103 PMC4609028__F1 Cell Cycle Regulators and Cell Death in Immunity ENSG00000149311 ENSG00000175054 PMC9511043__F4 Function and mechanism of histone Beta-hydroxybutyrylation in health and disease ENSG00000196591 PMC7867063__F2 Roles of NRF2 in cancer metabolism ENSG00000065833 ENSG00000065911 ENSG00000023909 PMC9196267__F3 Focusing on Formononetin: Recent Perspectives for its Neuroprotective Potentials ENSG00000142192 ENSG00000178573 ENSG00000136869 ENSG00000137845 ENSG00000079999 PMC4161521__F6 NFAT5/REDD1/mTOR/Notch pathway model ENSG00000102908 PMC11065696__F7 Mechanistic scheme of UBB in ccRCC ENSG00000185591 ENSG00000112715 PMC3996587__F1 Extended model for the cyclin/Cdk network driving the mammalian cell cycle ENSG00000145604 ENSG00000123374 ENSG00000117399 PMC7912633__F2 Activation of NFKB and regulation of downstream transcriptional antioxidant and pro-oxidant targets in the canonical pathway (adapted from [,,,,,,]) ENSG00000186716 ENSG00000173039 ENSG00000087250 ENSG00000132693 PMC7560826__F1 Janus-like role of proline metabolism in cancer ENSG00000100033 PMC12222209__F3 Aberrant localization of glycolytic enzymes on cancer MDR ENSG00000091317 ENSG00000067057 ENSG00000168036 ENSG00000171791 ENSG00000184207 ENSG00000118777 ENSG00000149311 ENSG00000074800 ENSG00000171720 ENSG00000132646 ENSG00000172977 ENSG00000146648 ENSG00000159399 PMC9011221__F3 Critical role and molecular mechanisms of ferroptosis in antioxidant systems: a narrative review ENSG00000163930 ENSG00000128272 ENSG00000151012 ENSG00000167468 ENSG00000162772 PMC7560826__F3 Janus-like role of proline metabolism in cancer ENSG00000128272 ENSG00000198793 ENSG00000100033 ENSG00000168610 PMC7560826__F4 Janus-like role of proline metabolism in cancer ENSG00000120868 ENSG00000168040 ENSG00000100033 PMC7576031__F2 Protein tyrosine phosphatase receptor type D (PTPRD)—mediated signaling pathways for the potential treatment of hepatocellular carcinoma: a narrative review ENSG00000138798 ENSG00000026508 ENSG00000168036 ENSG00000169429 ENSG00000168610 PMC3064425__F2 Dietary agents on the extrinsic and intrinsic pathways of apoptosis in prostate cancer ENSG00000168040 ENSG00000026103 PMC3518132__F8 Alkylphospholipid (ODPC)-induced raft-based inhibition of cell signaling ENSG00000213658 ENSG00000086730 PMC7576031__F3 Protein tyrosine phosphatase receptor type D (PTPRD)—mediated signaling pathways for the potential treatment of hepatocellular carcinoma: a narrative review ENSG00000291603 ENSG00000213658 ENSG00000198793 ENSG00000168610 PMC6258166__F6 Brain hyperserotonemia and Sert knockouts ENSG00000134376 ENSG00000118972 ENSG00000003436 ENSG00000144468 ENSG00000167333 ENSG00000153721 ENSG00000275331 ENSG00000100151 ENSG00000198754 ENSG00000136883 ENSG00000173757 ENSG00000179097 ENSG00000177606 ENSG00000152785 ENSG00000153930 ENSG00000179954 ENSG00000164362 ENSG00000146856 ENSG00000214160 ENSG00000080618 ENSG00000185591 ENSG00000158792 ENSG00000162777 ENSG00000146648 PMC8999556__F4 New Perspectives in Treating Acute Myeloid Leukemia: Driving towards a Patient-Tailored Strategy ENSG00000122025 ENSG00000157404 PMC6953121__F6 Schematic representation of the molecular interplay between S1T-dependent ER Ca2+ leak, ER stress, BAPP processing, and neuroinflammation likely contributing to AD setting and/or progression ENSG00000142192 ENSG00000128272 ENSG00000144895 PMC8980928__F6 Synovial tissue‐derived extracellular vesicles induce chondrocyte inflammation and degradation via NF‐KB signalling pathway: An in vitro study ENSG00000154736 PMC9436901__F8 Triptolide promotes autophagy to inhibit mesangial cell proliferation in IgA nephropathy via the CARD9/p38 MAPK pathway ENSG00000187796 ENSG00000057663 PMC4544949__F1 The flow diagram represents the sphingolipid metabolism pathways both in mammals and in yeast ENSG00000102172 ENSG00000135517 PMC7528698__F1 Transcriptional regulation of macropinocytosis ENSG00000167601 PMC8608863__F6 Molecular mechanism of Met against HCT116 cells ENSG00000132906 ENSG00000064012 ENSG00000164305 PMC3267756__F9 Coxiella burnetii Induces Apoptosis during Early Stage Infection via a Caspase-Independent Pathway in Human Monocytic THP-1 Cells ENSG00000102871 ENSG00000168040 PMC7600811__F13 Simplified representation of the Rho/ROCK signaling pathway ENSG00000163914 PMC4515393__F1 Ceramide metabolic pathways ENSG00000139624 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000102172 ENSG00000143418 PMC4662490__F3 Tracking sub-clonal TP53 mutated tumor cells in human metastatic renal cell carcinoma ENSG00000149212 ENSG00000085117 ENSG00000175793 ENSG00000164305 ENSG00000137801 ENSG00000149311 ENSG00000175054 ENSG00000172667 ENSG00000134574 ENSG00000136997 ENSG00000130222 ENSG00000123374 ENSG00000112378 ENSG00000177519 ENSG00000115107 ENSG00000026103 ENSG00000198625 PMC7600811__F12 Simplified representation of the canonical and non-canonical Wnt signaling pathway ENSG00000070831 ENSG00000168036 PMC5772162__F2 Progranulin ENSG00000003056 ENSG00000030582 ENSG00000106460 ENSG00000112561 PMC11489006__F3 Hippo pathway and crosstalk with other signaling pathways in CRC ENSG00000159224 ENSG00000168036 ENSG00000196628 PMC11489006__F2 Upstream regulators of Hippo signaling pathway in CRC ENSG00000198125 ENSG00000150457 ENSG00000131023 PMC11489006__F1 Hippo signaling pathway ENSG00000150457 ENSG00000131023 PMC5661614__F3 Simplified signaling pathway network where Wnt/Beta-catenin, Notch and Hedgehog pathways, along with critical transcription factors including Bmi-1, c-myc, Slug and Sox9, interact with one another and contribute to the maintenance of MaSC state ENSG00000168283 ENSG00000125398 ENSG00000168036 PMC8630984__F1 Mapping the molecular architecture required for lipid-binding pockets using a subset of established and orphan GPCRs ENSG00000122420 ENSG00000050628 ENSG00000119737 ENSG00000160013 ENSG00000125384 ENSG00000171049 ENSG00000168229 ENSG00000198670 ENSG00000138271 ENSG00000160951 PMC6249229__F5 13C metabolic flux analysis and RNASeq explain the overflow metabolism ENSG00000074800 ENSG00000122966 ENSG00000172005 ENSG00000186051 ENSG00000159399 PMC8395233__F1 Repair Mechanisms of the Neurovascular Unit after Ischemic Stroke with a Focus on VEGF ENSG00000291971 ENSG00000125538 ENSG00000162692 PMC2839281__F4 Pigmentation Pathway Evolution after Whole-Genome Duplication in Fish ENSG00000157404 ENSG00000138795 ENSG00000101440 ENSG00000135903 ENSG00000080166 ENSG00000107165 ENSG00000100146 ENSG00000124205 PMC9112456__F3 Noncoding RNAs related to the hedgehog pathway in cancer: clinical implications and future perspectives ENSG00000253352 ENSG00000128602 PMC9112456__F1 Noncoding RNAs related to the hedgehog pathway in cancer: clinical implications and future perspectives ENSG00000166813 ENSG00000128602 PMC3432272__F1 HIV’s double strike at the brain ENSG00000121966 PMC5003333__F1 Genetic Insights into Pulmonary Arterial Hypertension. Application of Whole-Exome Sequencing to the Study of Pathogenic Mechanisms ENSG00000074181 ENSG00000171303 PMC5069093__F1 Regulation of TLR folding, trafficking, and cleavage ENSG00000239732 ENSG00000172005 ENSG00000115020 ENSG00000172936 ENSG00000136869 ENSG00000110057 ENSG00000138760 PMC10909982__F5 Wnt/Beta-catenin signaling pathway potentially contributes to PTC progress ENSG00000134982 ENSG00000168036 PMC2630471__F5 DAF-2 Insulin-like Signaling Pathway Independently Regulates Aging and Immunity ENSG00000118515 PMC6721659__F3 Signaling pathways downstream urokinase-type plasminogen activator (uPA) receptor (uPAR) and its co-receptors ENSG00000291971 ENSG00000168610 ENSG00000122194 PMC6997353__F2 Ferroptosis: past, present and future ENSG00000161905 ENSG00000151012 ENSG00000167468 ENSG00000197429 ENSG00000111684 ENSG00000115107 ENSG00000057663 ENSG00000136381 ENSG00000079999 PMC7214843__F2 RAD51-mediated RF reversal (A) and an overview of replication fork restart mechanisms (B) ENSG00000138346 ENSG00000132646 ENSG00000165392 ENSG00000051180 ENSG00000077514 PMC5011625__F5 Endothelial Mechanosignaling: Does One Sensor Fit All? ENSG00000156299 ENSG00000162692 PMC8400620__F5 Comparative Pan-Genome Analysis of Oral Veillonella Species ENSG00000171174 ENSG00000117118 ENSG00000124370 ENSG00000173599 ENSG00000023697 ENSG00000082212 PMC3563505__F6 Functional partners of RB1 protein through STRING database ENSG00000112242 ENSG00000198176 ENSG00000135446 ENSG00000123374 ENSG00000162521 ENSG00000139687 ENSG00000282899 PMC7725906__F6 Action mechanism diagram of MXSG ENSG00000198793 ENSG00000168040 ENSG00000125347 ENSG00000276561 ENSG00000115415 ENSG00000130234 ENSG00000125538 ENSG00000136869 ENSG00000172936 ENSG00000127463 ENSG00000175104 ENSG00000064012 ENSG00000184216 ENSG00000164342 PMC9148527__F4 Plasmodium manipulates the expression of host long non-coding RNA during red blood cell intracellular infection ENSG00000049323 ENSG00000019991 ENSG00000137834 ENSG00000101146 ENSG00000105516 ENSG00000156574 ENSG00000134363 ENSG00000110651 ENSG00000111537 ENSG00000095739 ENSG00000100387 ENSG00000113558 ENSG00000136869 ENSG00000185591 PMC8966751__F4 Expression and Regulation Network of HDAC3 in Acute Myeloid Leukemia and the Implication for Targeted Therapy Based on Multidataset Data Mining ENSG00000144063 ENSG00000142192 ENSG00000285109 ENSG00000291971 ENSG00000173786 ENSG00000145321 ENSG00000137672 PMC4226790__F1 Development of mononuclear phagocytes ENSG00000168329 ENSG00000204103 ENSG00000174059 PMC6879860__F3 Schematic of the components of the integrated model ENSG00000122966 ENSG00000198793 ENSG00000172005 PMC9596219__F7 DAZAP1 facilitates the alternative splicing of KITLG to promote multiple myeloma cell proliferation via ERK signaling pathway ENSG00000049130 ENSG00000071626 PMC8899159__F5 Sex‐related differential susceptibility to ponatinib cardiotoxicity and differential modulation of the Notch1 signalling pathway in a murine model ENSG00000111537 ENSG00000105329 ENSG00000100906 ENSG00000150907 ENSG00000169047 ENSG00000177606 ENSG00000136997 ENSG00000168036 ENSG00000185591 ENSG00000007171 ENSG00000132170 PMC8213343__F1 Targeting Bruton’s Tyrosine Kinase in Inflammatory and Autoimmune Pathologies ENSG00000104856 ENSG00000107562 ENSG00000125347 ENSG00000105669 ENSG00000010671 ENSG00000177455 ENSG00000239732 ENSG00000111537 ENSG00000186716 ENSG00000172005 ENSG00000136869 ENSG00000172936 ENSG00000164342 PMC5849056__F1 Complement System and Preeclampsia ENSG00000039537 ENSG00000113600 ENSG00000291559 ENSG00000203710 ENSG00000196352 ENSG00000117335 ENSG00000166278 PMC3279748__F2 GSK-3 in NMDAR-LTD ENSG00000132906 ENSG00000174996 ENSG00000002330 ENSG00000006451 ENSG00000144118 ENSG00000168610 ENSG00000164305 PMC9672095__F4 Sirt3 deficiency induced down regulation of insulin degrading enzyme in comorbid Alzheimer’s disease with metabolic syndrome ENSG00000142192 ENSG00000171105 ENSG00000134982 ENSG00000156026 ENSG00000281879 ENSG00000119912 ENSG00000101425 PMC3432498__F1 Activation of the IKK-NFKB pathway by radiotherapy and chemotherapy ENSG00000149311 ENSG00000175104 PMC2933845__F4 Genistein inhibits critical pathways in cancer invasion ENSG00000162889 ENSG00000170365 PMC6925521__F1 NHEJ occurs at all stages of the cell cycle ENSG00000012048 ENSG00000163961 ENSG00000051180 PMC11512513__F3 Signaling pathway with UPS-related muscle wasting in cardiac cachexia ENSG00000158022 ENSG00000169047 ENSG00000198793 ENSG00000140443 PMC4795702__F2 Immune-Mediated Inflammation May Contribute to the Pathogenesis of Cardiovascular Disease in Mucopolysaccharidosis Type I ENSG00000011600 ENSG00000107798 ENSG00000146477 ENSG00000120885 ENSG00000057149 ENSG00000138744 ENSG00000095303 ENSG00000100979 ENSG00000163681 ENSG00000163017 ENSG00000022267 ENSG00000136235 ENSG00000079101 ENSG00000145936 ENSG00000198947 ENSG00000101425 ENSG00000106066 ENSG00000291560 ENSG00000283934 ENSG00000125148 ENSG00000163431 ENSG00000112562 ENSG00000129226 ENSG00000172403 ENSG00000025039 ENSG00000277943 ENSG00000143387 ENSG00000142892 ENSG00000163131 ENSG00000167996 ENSG00000146070 ENSG00000107165 ENSG00000154146 ENSG00000182253 PMC6051722__F4 Remnant-Like Particle Cholesterol, Low-Density Lipoprotein Triglycerides and Incident Cardiovascular Disease ENSG00000130164 ENSG00000042832 PMC11633002__F3 Network constructed based on the interaction test within the small cell lung cancer pathway from KEGG ENSG00000172037 PMC7189798__F2 Death receptor and mitochondrial apoptosis signaling pathways and blocking TNFR1-mediated apoptosis by c-FLIP ENSG00000078747 ENSG00000102871 ENSG00000171791 ENSG00000168040 ENSG00000127191 PMC6815639__F7 Pathview analysis of the NFKB signaling pathway ENSG00000149311 ENSG00000100290 ENSG00000226275 ENSG00000213658 ENSG00000102871 ENSG00000186716 ENSG00000150455 ENSG00000135517 ENSG00000145919 PMC9497241__F1 From Molecular Mechanisms to Therapeutics: Understanding MicroRNA-21 in Cancer ENSG00000128191 ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC11551531__F3 NFKB signaling pathway in macrophage polarization ENSG00000172936 PMC11551531__F5 Notch signaling pathway in macrophage polarization ENSG00000069812 ENSG00000172936 ENSG00000273529 ENSG00000114315 PMC10334824__F5 Prospective application of lncRNAs in the treatment of diabetic wounds ENSG00000162711 ENSG00000125398 ENSG00000117707 PMC11551531__F4 JAK/STAT signaling pathway in macrophage polarization ENSG00000105639 ENSG00000168610 PMC12223783__F11 Exogenous spermidine inhibits trastuzumab-induced cardiomyocyte pyroptosis Schematic illustration of trastuzumab-induced cardiomyocyte pyroptosis, and exogenous spermidine blocking the action of trastuzumab by promoting mitochondrial biosynthesis ENSG00000278718 ENSG00000142082 PMC11551531__F6 TGFB/SMAD signaling pathway in macrophage polarization ENSG00000137834 PMC12112249__F2 MDK oncogenic signaling network ENSG00000213420 ENSG00000198793 ENSG00000168036 ENSG00000168610 ENSG00000007171 PMC7702235__F2 miR regulatory mechanisms in experimental VCID ENSG00000220205 ENSG00000136531 ENSG00000132639 ENSG00000067715 PMC7251091__F8 Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathway ENSG00000137558 ENSG00000087245 ENSG00000112245 ENSG00000185591 ENSG00000100985 PMC4051924__F5 Top-ranked signaling networks related to Na+/K+/2Cl- cotransporter 1 downregulation according to ingenuity pathway analysis ENSG00000198901 ENSG00000094804 ENSG00000151503 ENSG00000277909 ENSG00000144554 ENSG00000134982 ENSG00000177606 ENSG00000140044 ENSG00000117399 ENSG00000282899 ENSG00000093009 PMC7762932__F1 PC and PE biosynthesis via two branches of the Kennedy pathway ENSG00000283781 ENSG00000110721 ENSG00000100288 ENSG00000173599 ENSG00000134255 PMC3735985__F1 Simplified schematic representation of the insulin and TOR signaling pathways as they have been described in mammals and for which orthologous components have been described in D PMC7312033__F2 IL-33, as pro-inflammatory and regulatory, on the central nervous system, liver, cardiovascular system, and pulmonary system ENSG00000137033 ENSG00000172936 ENSG00000175104 ENSG00000113525 ENSG00000184216 PMC4046645__F2 Overview of molecular pathways of oxidative stress and potential points of intervention in T cells in SLE ENSG00000198793 ENSG00000049768 PMC6033382__F2 Identification of a gene-expression predictor for diagnosis and personalized stratification of lupus patients ENSG00000172936 ENSG00000183479 ENSG00000115594 PMC7432853__F2 Different mechanisms of crosstalk between pancreatic ductal adenocarcinoma (PDAC) cancer cells and cancer-associated fibroblasts (CAFs) ENSG00000167601 ENSG00000156574 ENSG00000128342 ENSG00000164690 PMC8706168__F9 Homophilic Interaction of CD147 Promotes IL-6-Mediated Cholangiocarcinoma Invasion via the NFKB-Dependent Pathway ENSG00000163464 PMC10779012__F3 Mechanisms by which pitavastatin and metformin act to (A) turn cancer cells sensitive to chemotherapy and (B) help to revert the exhaustion state of CD8+ T cells ENSG00000198793 ENSG00000113161 PMC10706934__F1 Hypothetic signalling pathway triggered by FK506 ENSG00000170365 ENSG00000163217 PMC10779012__F2 Insulin-like growth factor 1 (IGF1) signaling pathway and major downstream effects on cancer cells ENSG00000002330 ENSG00000198793 ENSG00000140443 PMC10779012__F1 Metabolism of cholesterol within an ovarian cancer cell ENSG00000130164 ENSG00000113161 ENSG00000104549 ENSG00000160179 PMC9374094__F2 Targeting Indoleamine Dioxygenase and Tryptophan Dioxygenase in Cancer Immunotherapy: Clinical Progress and Challenges ENSG00000173599 ENSG00000106546 PMC5055212__F6 Gene network construction ENSG00000145604 ENSG00000087245 ENSG00000117020 ENSG00000138795 ENSG00000006451 ENSG00000172037 PMC7413390__F5 Canonical pathway represented by differentially expressed proteins in the BALF between progressive and non-progressive sarcoidosis implementing Overlapping Canonical Pathway functionality in IPA ENSG00000070831 ENSG00000163914 PMC5452982__F3 Regulation of muscle growth and regeneration by the immune system ENSG00000122180 ENSG00000148400 ENSG00000127191 ENSG00000125347 ENSG00000009709 ENSG00000108691 ENSG00000111537 ENSG00000115415 ENSG00000138755 ENSG00000189403 ENSG00000136869 ENSG00000172936 ENSG00000175104 PMC3132181__F2 Analysis of Individual Molecular Events of DNA Damage Response by Flow and Image Assisted Cytometry ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000123374 ENSG00000140464 PMC10745105__F6 Working model of GAH-dependent vascular repair ENSG00000170365 ENSG00000120693 PMC3132181__F1 Analysis of Individual Molecular Events of DNA Damage Response by Flow and Image Assisted Cytometry ENSG00000188486 ENSG00000149311 ENSG00000012048 PMC8004487__F3 Role of sphingolipid associated loci in major sphingolipid metabolic pathways ENSG00000182327 ENSG00000172292 ENSG00000285281 ENSG00000172296 PMC8834450__F2 Punicic Acid and Its Role in the Prevention of Neurological Disorders: A Review ENSG00000036530 ENSG00000198793 PMC10937367__F3 Effect of uridine on disease through O-GlcNAcylation ENSG00000142192 ENSG00000150907 ENSG00000198793 PMC8148009__F3 Musashi–1—A Stemness RBP for Cancer Therapy? ENSG00000145604 ENSG00000094804 ENSG00000112242 ENSG00000135446 ENSG00000123374 ENSG00000205250 ENSG00000105810 ENSG00000149554 ENSG00000282899 ENSG00000093009 PMC7837592__F3 Understanding Patterns of Brain Metastasis in Triple-Negative Breast Cancer and Exploring Potential Therapeutic Targets ENSG00000291971 ENSG00000146648 PMC6598292__F4 Main biosynthetic pathway for the biosynthesis of cellulose ENSG00000172005 PMC9029324__F2 Colorectal Cancer Diagnosis: The Obstacles We Face in Determining a Non-Invasive Test and Current Advances in Biomarker Detection ENSG00000087095 ENSG00000095739 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000173156 PMC6712175__F10 Schematic depicting the role of the C/EBP-Beta-lcn2 signaling pathway in MA-induced microglial apoptosis ENSG00000148346 ENSG00000172216 ENSG00000171791 PMC3270028__F6 Coronavirus Papain-like Proteases Negatively Regulate Antiviral Innate Immune Response through Disruption of STING-Mediated Signaling ENSG00000183735 ENSG00000088888 PMC6245940__F4 Dysfunctional HDL and atherosclerotic cardiovascular disease ENSG00000073060 ENSG00000042832 ENSG00000160179 PMC6664293__F2 KEGG AD pathway ENSG00000132906 ENSG00000291983 ENSG00000142192 ENSG00000002330 ENSG00000120868 ENSG00000168040 ENSG00000119912 ENSG00000164305 PMC6664293__F4 Network visualization of the calcium signaling pathway with expression and GWAS information ENSG00000149782 ENSG00000133019 ENSG00000110148 ENSG00000183943 ENSG00000163394 ENSG00000166501 ENSG00000115353 ENSG00000113749 ENSG00000160951 ENSG00000156049 ENSG00000130204 ENSG00000152495 ENSG00000170214 ENSG00000065361 ENSG00000140795 ENSG00000081248 ENSG00000078668 ENSG00000070961 ENSG00000158748 ENSG00000178363 ENSG00000198626 ENSG00000101306 ENSG00000182621 ENSG00000075073 ENSG00000099957 ENSG00000102468 ENSG00000007171 ENSG00000187848 ENSG00000156873 ENSG00000118160 ENSG00000221823 ENSG00000123360 ENSG00000164742 ENSG00000138193 ENSG00000083454 ENSG00000144935 ENSG00000169676 ENSG00000166863 ENSG00000154678 ENSG00000108405 ENSG00000145349 PMC2774770__F1 IL-4 induces an alternate pathway for BCR signalling ENSG00000095585 ENSG00000132906 ENSG00000002330 ENSG00000291971 ENSG00000177606 ENSG00000010671 PMC6944396__F1 Schematic of the proposed pathways whereby mitochondrial dysfunction impacts chronic obstructive pulmonary disease pathogenesis ENSG00000158828 ENSG00000168404 ENSG00000285379 PMC7308236__F6 Electric Stimulation Hyperthermia Relieves Inflammation via the Suppressor of Cytokine Signaling 3-Toll Like Receptor 4 Pathway in a Prostatitis Rat Model ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC4515050__F2 Activation of complement system by the amyloid plaques and its dual role in neuronal death ENSG00000288512 ENSG00000182326 PMC4905256__F8 Hierarchical protein binding at the rDNA locus and intersections with SUMO PMC7199433__F1 Mammalian kidney development ENSG00000143867 ENSG00000107485 ENSG00000126778 ENSG00000251493 PMC7290425__F2 Breast cancer cells use HSFs to drive various tumor-promoting mechanisms ENSG00000162783 ENSG00000284774 ENSG00000102878 ENSG00000080371 ENSG00000214160 PMC7290425__F3 Hepatocellular carcinoma (HCC) cells use HSFs to promote metabolic reprograming and cancer invasion ENSG00000284774 ENSG00000102878 ENSG00000159399 PMC8778098__F1 Replication and Spread of Oncolytic Herpes Simplex Virus in Solid Tumors ENSG00000164430 ENSG00000144895 ENSG00000175104 ENSG00000064012 ENSG00000184216 PMC10993167__F2 Related regulators of N6‐methyladenosine (m6A), 5‐methylcytosine (m5C) and N7‐methylguanosine (m7G) are involved in the signalling pathways of drug resistance during tumour treatment ENSG00000145388 ENSG00000253293 ENSG00000149968 ENSG00000091542 ENSG00000166670 ENSG00000146457 ENSG00000168610 PMC10993167__F5 Molecular mechanism of action of the FTO inhibitor 18097 ENSG00000166340 ENSG00000152348 ENSG00000142627 ENSG00000135423 ENSG00000134574 ENSG00000159388 ENSG00000170430 ENSG00000116717 ENSG00000078237 ENSG00000140464 ENSG00000285069 ENSG00000080546 PMC10993167__F6 FTO, ALKBH5 and pseudouridine synthase partial inhibitors and their inhibitory pathways are introduced ENSG00000245848 ENSG00000136997 ENSG00000170430 ENSG00000091542 ENSG00000278693 PMC8814829__F4 Comparison of porcine milk microRNA expression in milk exosomes versus whole swine milk and prediction of target genes ENSG00000177455 ENSG00000180210 ENSG00000012048 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198125 PMC4052186__F2 Cross-talk between mitochondrial metabolism and the IIS pathway is required to trigger the mitohormetic response in C PMC10976794__F3 Schematic overview of LMNA mutant pathways and MAPK3/1 (ERK1/2) initiated changes in cardiac remodeling ENSG00000160789 ENSG00000120875 ENSG00000198793 ENSG00000177606 ENSG00000018408 ENSG00000164690 PMC6061680__F1 Toolbar, graphical elements supported in SPV and the mTOR pathway ENSG00000141564 ENSG00000132170 PMC10976794__F2 Schematic overview of the Hippo signaling pathway ENSG00000175793 ENSG00000197905 ENSG00000198576 ENSG00000114978 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC4068945__F4 Nrf2-mediated oxidative stress response pathway is altered at multiple levels by DNA methylation in COPD airways ENSG00000100387 ENSG00000130522 ENSG00000167996 ENSG00000138356 ENSG00000197063 ENSG00000079999 PMC12187747__F2 ROS-induced cellular signalling in cancer cells ENSG00000002330 ENSG00000291971 ENSG00000271303 PMC6280103__F5 Cholesterol biosynthetic pathway and relative expression changes for genes encoding related enzymes ENSG00000110921 ENSG00000112972 ENSG00000172893 ENSG00000113161 ENSG00000167508 ENSG00000052802 ENSG00000160752 ENSG00000067064 ENSG00000132196 ENSG00000109929 ENSG00000149809 ENSG00000104549 ENSG00000075239 PMC5003378__F9 Statistical Techniques Complement UML When Developing Domain Models of Complex Dynamical Biosystems ENSG00000170458 ENSG00000172936 ENSG00000162924 ENSG00000175104 ENSG00000184216 PMC7925335__F2 Airway and small intestinal tuft cell signaling ENSG00000133019 ENSG00000283887 ENSG00000090402 ENSG00000198829 ENSG00000078369 ENSG00000214415 ENSG00000123104 ENSG00000070985 ENSG00000166090 ENSG00000127588 ENSG00000275565 ENSG00000137841 PMC471568__F2 Schematic illustrating the current working hypothesis on the hormonal servomechanism regulating uterine gland morphogenesis and function in the ovine endometrium during pregnancy ENSG00000112964 ENSG00000105397 ENSG00000113494 PMC11905258__F6 Potential therapeutic role of MSCs and EVs in treating CKD ENSG00000178860 ENSG00000019991 ENSG00000108691 ENSG00000149968 ENSG00000158481 ENSG00000132646 ENSG00000100985 PMC6448884__F5 GTS-21 has cell-specific anti-inflammatory effects independent of A7 nicotinic acetylcholine receptors ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000127191 PMC4807992__F1 Prostate cancer stem cells: the role of androgen and estrogen receptors ENSG00000291971 ENSG00000105204 PMC11545229__F8 ENAH-mediated OSCC progression ENSG00000291971 ENSG00000134982 ENSG00000138798 ENSG00000168036 ENSG00000146648 PMC2716750__F1 Gene regulatory networks in kidney development ENSG00000176692 ENSG00000145147 ENSG00000164056 ENSG00000075891 ENSG00000166278 ENSG00000185008 ENSG00000251493 PMC4813636__F1 Direct and indirect inhibition of MYC ENSG00000141867 ENSG00000136997 ENSG00000196367 PMC9595552__F4 Pyruvate metabolism–original version ENSG00000151376 ENSG00000262785 ENSG00000164904 ENSG00000063854 ENSG00000119640 ENSG00000120437 ENSG00000166816 ENSG00000076555 ENSG00000065833 ENSG00000072210 ENSG00000172497 ENSG00000170634 ENSG00000173599 ENSG00000103253 ENSG00000146701 ENSG00000082212 PMC2882796__F1 Does Activation of the Blood Coagulation Cascade Play a Role in Malaria Pathogenesis? ENSG00000125538 ENSG00000162692 PMC7697007__F7 TRIP12 in the DNA damage repair (DDR) pathway in response to DNA double-strand break (DSB) [,,,,,,] ENSG00000149311 ENSG00000012048 ENSG00000163961 ENSG00000153827 ENSG00000112130 PMC7697007__F6 TRIP12, ARF, and P53 pathway ENSG00000102871 ENSG00000153827 PMC10559929__F5 Explain the correlation among the chemical components, candidate targets, involved pathways and corresponding pharmacological effects of AGNHW ENSG00000143799 ENSG00000169245 ENSG00000172216 ENSG00000115415 ENSG00000173039 ENSG00000171791 ENSG00000100985 ENSG00000118777 ENSG00000164305 PMC7911310__F1 Methionine metabolism ENSG00000123505 ENSG00000116649 ENSG00000102172 PMC4097023__F6 Working model of apigenin-induced DNA damage ENSG00000188486 ENSG00000149311 ENSG00000113456 ENSG00000136997 ENSG00000282899 ENSG00000156273 PMC3696572__F1 Linking MLL and the HGF-MET signaling pathway in liver cancer ENSG00000019991 PMC12119490__F2 Tumor-derived vesicles and induced signaling modulation in various immune cells ENSG00000107562 ENSG00000128272 ENSG00000177606 ENSG00000136869 ENSG00000168610 ENSG00000121966 PMC6002513__F3 SIRTl/PGC-1A (FNDC5) pathway ENSG00000160097 ENSG00000142192 PMC10996278__F5 Major TCR signalling pathways ENSG00000065357 ENSG00000160185 ENSG00000114125 ENSG00000291603 ENSG00000070831 ENSG00000110448 ENSG00000173039 ENSG00000149091 ENSG00000166266 ENSG00000141968 ENSG00000101082 ENSG00000213658 ENSG00000010810 ENSG00000177606 ENSG00000113263 ENSG00000124181 PMC9114485__F2 Pathways Linking Nicotinamide Adenine Dinucleotide Phosphate Production to Endoplasmic Reticulum Protein Oxidation and Stress ENSG00000284320 ENSG00000065833 ENSG00000065911 ENSG00000100714 PMC7419058__F1 P53 activity by FBXO22 during senescence ENSG00000167196 ENSG00000066135 ENSG00000025293 PMC8804006__F1 Metabolic Transporters in the Peripheral Nerve—What, Where, and Why? ENSG00000110218 PMC10996278__F6 Critical genes and signalling pathways engage in T cell anti-tumour responses ENSG00000156127 ENSG00000137265 ENSG00000173039 ENSG00000107485 ENSG00000111321 ENSG00000198846 ENSG00000166266 ENSG00000049768 ENSG00000198286 PMC9040001__F6 Comparative transcriptomics discloses the regulatory impact of carbon/nitrogen fermentation on the biosynthesis of Monascus kaoliang pigments ENSG00000042832 ENSG00000062485 ENSG00000026103 PMC2913631__F3 Schematic model of crosstalk between PPARG and Wnt-5a signaling in MSC ENSG00000087095 ENSG00000143379 PMC8888930__F1 Microglia Polarization From M1 to M2 in Neurodegenerative Diseases ENSG00000172936 ENSG00000136869 ENSG00000096717 ENSG00000175104 PMC6462501__F2 Signaling network of the MSC components related to protein synthesis and cancer ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000198793 ENSG00000112715 ENSG00000127191 ENSG00000026103 PMC8632544__F1 Wnt/Beta-Catenin-Dependent Transcription in Autism Spectrum Disorders ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000177606 ENSG00000168036 PMC11545787__F1 Effect of Probiotics on Gastrointestinal Health Through the Aryl Hydrocarbon Receptor Pathway: A Systematic Review ENSG00000140505 ENSG00000106546 PMC3793056__F5 Predictive metabolic pathway of biosynthesis in M ENSG00000112977 ENSG00000116984 PMC2581573__F1 The IL-1 signaling pathway ENSG00000172936 ENSG00000175104 PMC6462501__F5 Systematic association of the MSC components with mTOR and DNA repair pathways ENSG00000104365 ENSG00000171105 ENSG00000198793 ENSG00000156976 ENSG00000025039 ENSG00000149311 ENSG00000175054 ENSG00000113384 ENSG00000117020 ENSG00000162409 ENSG00000132383 ENSG00000118515 ENSG00000051180 ENSG00000106305 ENSG00000140464 PMC4552335__F6 Proposed pathways through which ethanol administration elicits alterations in cytokine gene expression ENSG00000170458 ENSG00000189403 ENSG00000136869 PMC9301130__F2 Effect of Lithocholic Acid on the Gut-Liver Axis ENSG00000138378 ENSG00000115415 PMC6761006__F1 Glucose metabolism via hexosamine biosynthesis pathway links amino acid, fatty acid and nucleotide metabolisms to regulate cell physiology and pathology via protein O-GlcNAcylation ENSG00000147162 ENSG00000198408 PMC7040003__F5 Differential expressed genes in the hormone-mediated ovarian maturation pathways in the polychaete-fed group ENSG00000109163 ENSG00000134982 ENSG00000145782 ENSG00000117399 PMC8107278__F1 Using Biosensors to Study Protein–Protein Interaction in the Hippo Pathway ENSG00000131023 ENSG00000291442 PMC8750061__F5 Co-Expression Analysis of microRNAs and Proteins in Brain of Alzheimer’s Disease Patients ENSG00000101871 PMC9606346__F7 Combined analysis of the transcriptome and proteome of Eucommia ulmoides Oliv. (Duzhong) in response to Fusarium oxysporum ENSG00000128272 ENSG00000171791 PMC10856016__F2 Phosphatidylinositol 3-kinase (PI3K) protein kinase B (AKT)/mammalian target of rapamycin (mTOR), PI3K/AKT/mTOR, and mitogen-activated protein kinase (MAPK) signaling pathway activation in gastric cancer (GC) ENSG00000066468 ENSG00000002330 ENSG00000065361 ENSG00000150907 ENSG00000198793 ENSG00000145321 ENSG00000121879 ENSG00000146648 PMC5652672__F3 Somatic mutations in salivary duct carcinoma and potential therapeutic targets ENSG00000198793 ENSG00000121879 PMC5652672__F2 Somatic mutations in salivary duct carcinoma and potential therapeutic targets PMC6489558__F7 Hypothesis: after surgery, PTFs can stimulate surrounding hepatocytes to transform into a malignant phenotype, leading to hepatocarcinogenesis and tumor recurrence ENSG00000168610 PMC9243434__F1 Sigma-1 Receptors in Depression: Mechanism and Therapeutic Development ENSG00000198793 ENSG00000100219 PMC5726598__F8 PIK3CA cellular signaling pathway ENSG00000198793 ENSG00000146648 PMC9011221__F1 Critical role and molecular mechanisms of ferroptosis in antioxidant systems: a narrative review ENSG00000167468 ENSG00000197429 ENSG00000111371 ENSG00000115107 ENSG00000115419 PMC5007815__F7 MAPK/MSK1/Histone H3 pathway on target gene transcription ENSG00000125968 PMC3847587__F5 Significantly affected canonical pathway “Interferon signaling”, as determined by IPA™ analysis ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000125347 ENSG00000230034 PMC7068598__F2 Emerging signaling pathways in CSCs ENSG00000137033 ENSG00000198793 ENSG00000136997 ENSG00000168036 ENSG00000132478 ENSG00000096717 ENSG00000128602 ENSG00000168610 ENSG00000146648 ENSG00000136231 PMC4489702__F1 miRNAs as biological and clinical determinants in colorectal cancer ENSG00000183742 PMC8106640__F6 PLPPR1 modulates RhoA-ROCK pathway ENSG00000276539 ENSG00000198670 PMC4090290__F1 Epidermal growth factor receptor (EGFR) pathway activation during HNSCC carcinogenic process ENSG00000163235 ENSG00000138798 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC5458189__F7 Novel Akt activator SC-79 is a potential treatment for alcohol-induced osteonecrosis of the femoral head ENSG00000198793 ENSG00000168036 PMC10224166__F3 Anti-inflammatory effect and mechanism of atractylenolide I and III ENSG00000172936 ENSG00000136869 ENSG00000168610 ENSG00000171051 PMC3157425__F4 Apoptosis Induced by Piroxicam plus Cisplatin Combined Treatment Is Triggered by p21 in Mesothelioma ENSG00000108679 ENSG00000100526 PMC10224166__F4 Anti-cancer effects and mechanism of atractylenolide I, II, and III ENSG00000002330 ENSG00000181019 ENSG00000198793 ENSG00000123374 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC4823096__F7 Novel PAD4/SOX4/PU.1 signaling pathway is involved in the committed differentiation of acute promyelocytic leukemia cells into granulocytic cells ENSG00000122966 ENSG00000124766 ENSG00000280908 PMC7671546__F8 G ATA2 mediates the negative regulation of the prepro-thyrotropin-releasing hormone gene by liganded T3 receptor B2 in the rat hypothalamic paraventricular nucleus ENSG00000170893 ENSG00000179348 ENSG00000168610 ENSG00000134200 PMC10138955__F5 Comparative Genomic Analysis of a Methylorubrum rhodesianum MB200 Isolated from Biogas Digesters Provided New Insights into the Carbon Metabolism of Methylotrophic Bacteria ENSG00000172005 ENSG00000105656 PMC7764203__F5 Metabolic pathways involved in lactate-based or ethanol-based chain elongation and production of acetate, n-butyrate, iso-butyrate, and n-caproate as predicted from the genome annotation of strains BL-3, BL-4, and BL-6 ENSG00000196839 ENSG00000105379 PMC11355043__F1 Current model of the blood coagulation cascade, depicting NOACs’ mechanism of action ENSG00000003436 ENSG00000134982 ENSG00000122194 PMC7039088__F1 KEGG pathway map of the JAK-STAT signaling pathway obtained from the KEGG website ENSG00000198793 ENSG00000131095 PMC5517452__F7 A putative signaling pathway of parkin expression induced by MIDN ENSG00000128272 ENSG00000167470 PMC4949713__F3 WNT/B‐catenin signalling pathway ENSG00000134982 ENSG00000168036 PMC7784988__F6 Myofiber necroptosis promotes muscle stem cell proliferation via releasing Tenascin-C during regeneration ENSG00000041982 ENSG00000138798 ENSG00000146648 PMC8130321__F5 Signature RNAS and related regulatory roles in type 1 diabetes mellitus based on competing endogenous RNA regulatory network analysis ENSG00000165898 ENSG00000041353 ENSG00000241945 ENSG00000124882 ENSG00000040933 ENSG00000181104 ENSG00000150867 ENSG00000187266 ENSG00000062485 ENSG00000078304 PMC4992754__F1 Sonic hedgehog (SHH) signaling pathway ENSG00000136997 ENSG00000171791 ENSG00000128602 ENSG00000118971 PMC10473922__F9 Huangqin decoction alleviates lipid metabolism disorders and insulin resistance in nonalcoholic fatty liver disease by triggering Sirt1/NFKB pathway ENSG00000135218 ENSG00000096717 ENSG00000026103 PMC8742202__F5 SMAD4 contributes to chondrocyte and osteocyte development ENSG00000170365 ENSG00000281324 ENSG00000125398 ENSG00000162337 ENSG00000174804 ENSG00000168036 ENSG00000163501 PMC10906782__F8 Different biological activities of DCV-derived soluble CPE and sEV-CPE ENSG00000168830 ENSG00000171791 PMC9121642__F2 Compound Kushen injection inhibits EMT of gastric cancer cells via the PI3K/AKT pathway ENSG00000142192 ENSG00000081041 ENSG00000198793 ENSG00000087085 ENSG00000173083 ENSG00000007908 ENSG00000213341 ENSG00000143228 ENSG00000112715 ENSG00000171033 ENSG00000104368 ENSG00000132170 ENSG00000150782 ENSG00000169245 ENSG00000132646 ENSG00000177606 ENSG00000136997 ENSG00000159399 ENSG00000127948 PMC2716751__F2 The concept of angiotensin II-growth factor cross-talk in ureteric bud morphogenesis ENSG00000070193 ENSG00000176692 ENSG00000145147 ENSG00000164056 ENSG00000140285 ENSG00000075891 ENSG00000166278 ENSG00000185008 ENSG00000146648 ENSG00000251493 ENSG00000276799 PMC5516298__F1 FAM13A regulates the CPT1A–FAO pathway in chronic obstructive pulmonary disease (COPD) ENSG00000157184 ENSG00000138640 PMC7526732__F4 Plasma Dehydroepiandrosterone Sulfate and Cardiovascular Disease Risk in Older Men and Women ENSG00000173714 ENSG00000142655 ENSG00000162729 ENSG00000139610 ENSG00000133110 ENSG00000108947 ENSG00000175315 ENSG00000142615 ENSG00000173467 ENSG00000088926 ENSG00000187244 ENSG00000130175 PMC9266892__F1 Contribution of Wnt Signaling to Vascular Complications in Type 2 Diabetes Mellitus ENSG00000134982 PMC7158706__F4 Upregulation of interferon signaling pathways ENSG00000068079 ENSG00000213928 ENSG00000180447 ENSG00000111537 ENSG00000105397 ENSG00000033800 ENSG00000125347 ENSG00000230034 PMC9220294__F8 Activation of the MAC1-ERK1/2-NOX2 Pathway Is Required for LPS-Induced Sustaining Reactive Microgliosis, Chronic Neuroinflammation and Neurodegeneration ENSG00000169704 ENSG00000189403 ENSG00000172936 ENSG00000136869 PMC8671294__F1 Purinergic Signaling in the Regulation of Gout Flare and Resolution ENSG00000162711 ENSG00000172936 ENSG00000087842 PMC4138046__F1 Multi-Level Kinetic Model Explaining Diverse Roles of Isozymes in Prokaryotes ENSG00000261701 ENSG00000115271 PMC6978517__F7 TGFB2-induced formation of lipid droplets supports acidosis-driven EMT and the metastatic spreading of cancer cells ENSG00000151726 ENSG00000135218 ENSG00000170558 ENSG00000285482 PMC8226215__F1 Assembling Disease Networks From Causal Interaction Resources ENSG00000138798 ENSG00000146648 PMC8107841__F6 Investigation of the association between imbalance of the intestinal flora and infantile spasms: a pilot case-control study ENSG00000175536 ENSG00000173239 PMC8560834__F8 Incorporating Transcriptomic-Metabolomic analysis reveal the effect of ultrasound on ethanol production in Saccharomyces Cerevisiae ENSG00000146701 PMC8254453__F6 Circulating mtDNA-mediated acute lung injury during sepsis due to STING-dependent autophagy dysfunction ENSG00000183735 ENSG00000164430 PMC3539261__F2 Initiation of the inflammatory response to monosodium urate crystals (MSU) by the innate immune system ENSG00000162711 ENSG00000125538 PMC9266554__F0 3-keto-DON, but Not 3-epi-DON, Retains the in Planta Toxicological Potential after the Enzymatic Biotransformation of Deoxynivalenol ENSG00000144063 ENSG00000149311 ENSG00000083093 ENSG00000084093 ENSG00000002330 ENSG00000182185 ENSG00000108384 ENSG00000197299 ENSG00000131096 ENSG00000138385 ENSG00000139618 ENSG00000084774 PMC3547110__F3 Amplifying phase ENSG00000095585 ENSG00000033327 ENSG00000197943 ENSG00000175104 ENSG00000135605 ENSG00000010671 PMC5076476__F2 Pathogenic viruses target RLR regulation for immune evasion ENSG00000183735 ENSG00000088888 ENSG00000159335 ENSG00000121060 ENSG00000057663 PMC5573165__F1 The polyamine-hypusine pathway ENSG00000095059 ENSG00000288145 ENSG00000129932 ENSG00000136997 ENSG00000123505 ENSG00000128602 ENSG00000116649 ENSG00000102172 PMC6321707__F1 Putative Celangulin V biosynthetic pathway in C ENSG00000067064 ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC7797476__F4 CILP function and regulation in NP cells by TGFB and IGF-1 ENSG00000138615 ENSG00000128928 PMC8786143__F1 Quantitative Alterations in Complement Alternative Pathway and Related Genetic Analysis in Severe Phenotype Preeclampsia ENSG00000244414 ENSG00000244731 ENSG00000166278 ENSG00000132693 ENSG00000236625 PMC3077819__F2 Widespread extracellular matrix (ECM) pathway silencing by DNA hypermethylation in colon cancer ENSG00000100234 ENSG00000145681 ENSG00000149968 ENSG00000113140 ENSG00000138829 ENSG00000168036 ENSG00000136235 ENSG00000122194 ENSG00000101680 ENSG00000156535 PMC3217183__F5 Signaling components of the RAS/MAPK pathway found to harbor activating mutations in various types of nevi and melanoma ENSG00000157764 ENSG00000088256 PMC4418726__F3 RNA-Seq Based De Novo Transcriptome Assembly and Gene Discovery of Cistanche deserticola Fleshy Stem ENSG00000084774 PMC7999169__F6 mRNA-lncRNA co-expression network of the blue module ENSG00000136158 ENSG00000081041 ENSG00000117228 ENSG00000187608 ENSG00000127325 ENSG00000109321 ENSG00000148926 ENSG00000010818 ENSG00000185885 ENSG00000162772 ENSG00000161955 ENSG00000156802 ENSG00000124882 ENSG00000134824 ENSG00000135363 ENSG00000104447 ENSG00000114315 PMC9277795__F8 circCYP24A1 promotes Docetaxel resistance in prostate Cancer by Upregulating ALDH1A3 ENSG00000184254 ENSG00000198793 ENSG00000123908 PMC3607621__F1 Dark face of AMPK as an essential tumor promoter ENSG00000131473 ENSG00000065833 ENSG00000110931 ENSG00000026103 PMC3336066__F2 Double-strand break repair in mammalian cells ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000138346 ENSG00000197299 ENSG00000051180 PMC2805706__F3 Brain foods: the effects of nutrients on brain function ENSG00000198793 PMC11667780__F4 mTORis reduce the number and function of Tregs via multiple mechanisms to inhibit tumor progression ENSG00000049768 PMC2842986__F2 General synthetic route to the racemic vinyl, ethyl, n-propyl, n-butyl, i-butyl, 2-propenyl, allyl, ethynyl, and 1-propynyl mevalonate lactone analogues (1a–e, g, i–k) is shown in ENSG00000015285 ENSG00000166278 PMC2984612__F1 Cellular FLICE-inhibitory protein: an attractive therapeutic target? ENSG00000168040 ENSG00000084774 ENSG00000026103 PMC4707216__F4 Met inactivation by S-allylcysteine suppresses the migration and invasion of nasopharyngeal cancer cells induced by hepatocyte growth factor ENSG00000019991 ENSG00000087245 ENSG00000291971 ENSG00000100985 PMC5128915__F2 THD-Module Extractor: An Application for CEN Module Extraction and Interesting Gene Identification for Alzheimer’s Disease ENSG00000149311 ENSG00000175054 ENSG00000136997 ENSG00000123374 ENSG00000112378 ENSG00000164305 PMC5166507__F1 Model for the cycling of ULK1 protein levels, which modulates the oscillatory mode of the autophagy response during prolonged starvation ENSG00000177169 ENSG00000198793 PMC11667780__F3 Mechanisms underlying mTOR regulation in macrophage differentiation ENSG00000155792 PMC7972846__F7 Effect of ECT on MAPK, AhR, and NFKB signaling pathways in CS-induced lung injury in mice ENSG00000106546 ENSG00000062485 PMC3008185__F1 Two-loop model of iADE ENSG00000183735 ENSG00000187608 ENSG00000115415 ENSG00000131323 ENSG00000168610 PMC11667780__F2 mTORis inhibit tumor metastasis to the lungs by suppressing EMT, tumor proliferation, and angiogenesis, whereas CNIs exert the opposite effect ENSG00000119888 ENSG00000155792 ENSG00000167965 PMC8146403__F1 Transport Proteins Enabling Plant Photorespiratory Metabolism ENSG00000284320 ENSG00000089159 PMC5954140__F7 Gene regulation of ESRRG and Wnt signaling ENSG00000138795 ENSG00000168036 ENSG00000196628 PMC3089562__F7 Proposed model of how endocardial Jarid2 expression regulates myocardial development ENSG00000148400 ENSG00000008083 ENSG00000178568 PMC9393759__F2 Circulating inflammatory cells in patients with metastatic breast cancer: Implications for treatment ENSG00000198053 ENSG00000184371 ENSG00000121807 ENSG00000078098 PMC6274312__F5 Interactomic analysis by Ingenuity Pathway Analysis (IPA) of significant molecules ENSG00000188486 ENSG00000124102 ENSG00000159128 ENSG00000168395 ENSG00000109320 ENSG00000173039 ENSG00000145777 ENSG00000130159 ENSG00000100429 ENSG00000140465 ENSG00000080546 ENSG00000134321 ENSG00000138674 ENSG00000109084 ENSG00000026508 ENSG00000188130 ENSG00000173846 PMC11825815__F2 Macrophages in the progression of CP to PC: M2 macrophages interact with PSCs and contribute to the fibrotic process in the pancreas ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC5119517__F1 The PI3K/mTOR signaling pathway PMC3875464__F3 PKG regulation of TRPC current and signaling ENSG00000039537 ENSG00000144935 ENSG00000117152 ENSG00000116741 PMC11953522__F2 String pathway analysis of the significant genes with k means clustering → Red: apoptosis network (Bcl-2 family protein complex), yellow: Aspartyl transferase activity, Green: S100 protein pathway (1 ENSG00000100290 ENSG00000143546 ENSG00000110395 ENSG00000205846 ENSG00000153094 ENSG00000163220 ENSG00000163221 ENSG00000142273 ENSG00000258643 ENSG00000135116 ENSG00000160999 ENSG00000104081 PMC4286392__F9 Notch and Eph / ephrin signaling pathways of non-myelinating oligodendrocytes relative to corresponding ones of their myelinating counterpart ENSG00000067141 ENSG00000135547 ENSG00000107562 ENSG00000160145 ENSG00000148400 ENSG00000144455 ENSG00000188342 ENSG00000196562 ENSG00000038002 ENSG00000070669 ENSG00000139352 ENSG00000121966 ENSG00000137947 ENSG00000142731 ENSG00000119396 PMC5579652__F1 MYD88-mediated TLR4 signaling pathway results in the production of pro-inflammatory cytokines ENSG00000170458 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC8943949__F7 Ciclopirox targets cellular bioenergetics and activates ER stress to induce apoptosis in non-small cell lung cancer cells ENSG00000087245 ENSG00000135446 ENSG00000170558 ENSG00000100985 ENSG00000164305 PMC4665974__F4 Overexpression of Human Fatty Acid Transport Protein 2/Very Long Chain Acyl-CoA Synthetase 1 (FATP2/Acsvl1) Reveals Distinct Patterns of Trafficking of Exogenous Fatty Acids ENSG00000173599 PMC8160449__F1 Therapeutic Potential of Exploiting Autophagy Cascade Against Coronavirus Infection ENSG00000177169 ENSG00000188554 ENSG00000123395 ENSG00000083290 ENSG00000126775 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC6412963__F1 Overview of cholesterol trafficking in enterocytes ENSG00000138075 ENSG00000130164 ENSG00000015520 ENSG00000143921 PMC6808435__F6 RNA-Seq analysis reveals an essential role of tyrosine metabolism pathway in response to root-rot infection in Gerbera hybrida PMC4590592__F8 Schematic view of the signaling pathways involved in healthy and CMML monocytes during CSF1-induced differentiation ENSG00000177169 ENSG00000171631 ENSG00000149782 ENSG00000110931 ENSG00000184371 ENSG00000197943 ENSG00000132356 PMC7075910__F7 Protein interactions for ECM and summary of regulators ENSG00000108684 ENSG00000111321 ENSG00000166147 ENSG00000139055 ENSG00000121068 ENSG00000196352 ENSG00000108821 ENSG00000117228 ENSG00000085117 ENSG00000137033 ENSG00000173917 ENSG00000079150 ENSG00000189056 ENSG00000077279 ENSG00000163453 ENSG00000221869 ENSG00000162849 ENSG00000145777 ENSG00000007908 ENSG00000005243 ENSG00000163661 ENSG00000148848 ENSG00000033100 ENSG00000123989 ENSG00000164107 ENSG00000100234 ENSG00000019991 ENSG00000184347 ENSG00000139567 ENSG00000102359 ENSG00000168032 ENSG00000135914 ENSG00000140937 ENSG00000154133 ENSG00000145623 ENSG00000108688 ENSG00000152049 ENSG00000185591 ENSG00000182463 ENSG00000118946 ENSG00000144057 ENSG00000003436 ENSG00000149380 ENSG00000291559 ENSG00000113140 ENSG00000173039 ENSG00000134871 ENSG00000163217 ENSG00000108691 ENSG00000177606 ENSG00000291748 ENSG00000128285 PMC8160449__F2 Therapeutic Potential of Exploiting Autophagy Cascade Against Coronavirus Infection ENSG00000188554 ENSG00000130234 ENSG00000184012 PMC9184561__F7 Mechanism of sorafenib-inhibiting inflammation induced by LPS ENSG00000175104 PMC10149254__F5 Chemical composition of pigeon crop milk and factors affecting its production: a review ENSG00000173757 PMC7097628__F3 Rewiring cellular networks by members of the Flaviviridae family ENSG00000128272 ENSG00000144895 ENSG00000115415 ENSG00000110048 ENSG00000113161 ENSG00000169710 ENSG00000100219 ENSG00000145782 ENSG00000168610 ENSG00000215301 PMC3427795__F1 Interplay between FOXO, TOR, and Akt ENSG00000117020 ENSG00000117525 ENSG00000149212 PMC7068675__F5 Candidate drug repurposing based on dysregulated lnc-FFLs associated with GDM ENSG00000002330 ENSG00000136997 ENSG00000168036 ENSG00000112394 PMC6367546__F8 Schematic illustrating that CD9/ADAM17 axis plays a key role in keratinocyte migration via activation of EGFR/ERK signaling pathway ENSG00000113070 ENSG00000138798 ENSG00000010278 ENSG00000146648 PMC4621978__F9 D receptor‐mediated ERK1/2 activation via the PKCD/EGFR/B‐arrestin2 signalling pathway in response to specific agonist stimulation ENSG00000291971 ENSG00000113070 ENSG00000146648 PMC2808051__F1 Summary of the insulin/IGF signaling pathway, using the terminology for mammalian systems ENSG00000149311 ENSG00000147162 ENSG00000198793 PMC3206266__F3 Androgen biosynthesis in the prostate ENSG00000151632 ENSG00000203857 ENSG00000187134 PMC3281420__F1 Schematic overview of the multifunctional roles of c-FLIP in the TRAIL-triggered apoptosis pathway as well as activating various anti-apoptotic and cell survival signaling pathways ENSG00000056558 ENSG00000168040 ENSG00000127191 PMC2808051__F6 Mammalian target of rapamycin (mTOR) activation pathway ENSG00000198793 ENSG00000284161 ENSG00000167658 ENSG00000166278 PMC8198874__F3 Comprehensive Review: Sphingolipid Metabolism and Implications of Disruption in Sphingolipid Homeostasis ENSG00000100422 ENSG00000135454 ENSG00000173599 ENSG00000102172 PMC3756396__F1 Simplified scheme of the possible involvement of cAMP/PKA pathway in cancer ENSG00000164690 ENSG00000171791 PMC7183669__F9 miR-135b-regulation of JADE-1 inhibited the growth of cancer stem cells and tumors in PC via the AKT/mTOR pathway ENSG00000198793 PMC4867329__F2 Molecular mechanisms involved in glucosensing in the gastrointestinal tract ENSG00000169962 ENSG00000179002 ENSG00000159224 PMC7289296__F4 1A, 25-dihydroxyvitamin D3 promotes the translocation of Beta-catenin from the nucleus to the plasma membrane, and competes with T-cell transcription factor 4 (TCF4) for Beta-catenin binding ENSG00000168036 PMC4737482__F1 Network mapping of genes with >5-fold expression change using IPA ENSG00000169245 ENSG00000100290 ENSG00000117650 ENSG00000140379 ENSG00000175832 ENSG00000173039 ENSG00000205250 ENSG00000166886 PMC8348889__F1 SARS-CoV-2 and Acute Cerebrovascular Events: An Overview ENSG00000003436 ENSG00000110799 ENSG00000130234 ENSG00000122194 PMC6604619__F10 Identification of a novel function of hepatic long-chain acyl-CoA synthetase-1 (ACSL1) in bile acid synthesis and its regulation by bile acid-activated farnesoid X receptor ENSG00000151726 ENSG00000180432 ENSG00000135929 PMC5602287__F1 Summary of iAs effects on regulators of G1/(S)phase ENSG00000123374 ENSG00000282899 ENSG00000175305 PMC8102306__F1 Intrinsic drivers of metabolic pathways ENSG00000074800 ENSG00000136997 ENSG00000113161 PMC5285325__F3 Nuclear Dynamics of Heterochromatin Repair ENSG00000198887 ENSG00000145321 ENSG00000140464 PMC5499621__F10 The scheme for target of 4-O-Methylhonokiol on the TGFB pathway ENSG00000086991 ENSG00000185591 PMC7146986__F9 Mechanism investigation of miR-195 in different stroke mediators, with a particular emphasis on the KLF5/ JNK axis ENSG00000168329 ENSG00000070831 ENSG00000075213 PMC5085216__F8 Prevention effect of rare ginsenosides against stress-hormone induced MTOC amplification ENSG00000012048 ENSG00000134086 ENSG00000134363 ENSG00000051180 PMC8450353__F7 Cyclosporin A: A Repurposable Drug in the Treatment of COVID-19? ENSG00000162889 ENSG00000130234 ENSG00000184012 ENSG00000172936 ENSG00000164342 PMC6470667__F1 IL-1, IL-36, IL-37, and IL-38 receptors and intracellular signaling ENSG00000125538 ENSG00000136696 ENSG00000136694 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000115594 PMC8194077__F1 Therapeutic Targeting of Notch Signaling: From Cancer to Inflammatory Disorders ENSG00000128917 ENSG00000184916 PMC4024417__F1 Crosstalk between TGFB signaling and the renin-angiotensin system in fibrosis ENSG00000130234 PMC2978721__F8 Functional Interaction between Acyl-CoA Synthetase 4, Lipooxygenases and Cyclooxygenase-2 in the Aggressive Phenotype of Breast Cancer Cells PMC6670035__F6 Proposed role of TGFB1 in HASM cell contractile responses in asthma ENSG00000113448 ENSG00000106546 PMC9695027__F3 NTRK Gene Fusions in Solid Tumors and TRK Inhibitors: A Systematic Review of Case Reports and Case Series ENSG00000198793 PMC6020112__F2 Mechanisms involved in osteocyte mechanotransduction ENSG00000281324 ENSG00000162337 PMC5815915__F8 Nrf2/ARE pathway attenuates oxidative and apoptotic response in human osteoarthritis chondrocytes by activating ERK1/2/ELK1-P70S6K-P90RSK signaling axis ENSG00000002330 ENSG00000086991 ENSG00000171791 PMC5867005__F1 UPR signalling pathway ENSG00000128272 ENSG00000144895 ENSG00000185591 ENSG00000167182 PMC7066582__F3 Retinoid signaling pathways leading to lung cancer stem cell (CSC) differentiation and cell cycle arrest ENSG00000141448 ENSG00000146648 ENSG00000145113 PMC3995826__F2 Pathways for (A) Maturity Onset Diabetes of the Young (hsa04950), (B) type 2 diabetes (hsa04930), and (C) Notch signaling pathway (hsa04330); adapted from Kanehisa, et al ENSG00000171105 ENSG00000184384 ENSG00000067606 ENSG00000198793 ENSG00000196782 ENSG00000100060 ENSG00000182759 ENSG00000090932 ENSG00000106003 PMC7457384__F1 Source of IL-33 and the IL-33/ST2 signaling pathway ENSG00000137033 ENSG00000172936 PMC6555088__F3 GSK-3 signalling in heart ENSG00000137834 ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC4535771__F1 Using DeDaL for visualizing Fanconi pathway in breast cancer ENSG00000197299 PMC10949534__F11 Integrating network pharmacology with molecular docking to rationalize the ethnomedicinal use of Alchornea laxiflora (Benth.) Pax & K. Hoffm. for efficient treatment of depression ENSG00000291971 ENSG00000168610 ENSG00000146648 PMC10949534__F10 KEGG pathway analysis: (A) PI3K-AKT signaling pathway and (B) MAPK signaling pathway ENSG00000177455 ENSG00000087095 ENSG00000103479 ENSG00000142192 ENSG00000002330 ENSG00000102871 ENSG00000198793 ENSG00000104894 ENSG00000081189 ENSG00000026103 PMC6861014__F7 Model depicting the regulation of the host cellular response to systemic LM infection by C5aR1 and C5aR2 ENSG00000134830 ENSG00000197405 PMC3061251__F1 Viral infection triggers the IFNB signal transduction pathway of the host innate immune system, activating the antiviral state ENSG00000105397 ENSG00000115415 ENSG00000164342 ENSG00000142166 PMC6340394__F4 Black-Box Illuminated: Signals and Signaling ENSG00000117525 ENSG00000069869 ENSG00000198435 ENSG00000136997 ENSG00000105810 ENSG00000169375 PMC10239166__F1 Transcriptional regulation on effector T cells in the pathogenesis of psoriasis ENSG00000134460 ENSG00000049768 PMC8750102__F8 Amino Acid Metabolism in Cancer Drug Resistance ENSG00000151012 ENSG00000115419 PMC6068465__F5 p53 signaling pathway ENSG00000149311 ENSG00000175054 ENSG00000136997 ENSG00000112378 ENSG00000196470 ENSG00000164305 ENSG00000026103 PMC2637179__F2 Role of IRS-1 in insulin and IGF-1 signaling ENSG00000044090 ENSG00000169047 ENSG00000198793 PMC8750102__F6 Amino Acid Metabolism in Cancer Drug Resistance ENSG00000092621 ENSG00000135069 ENSG00000116761 PMC12152130__F4 Relationship between cuproptosis and autophagy ENSG00000177169 ENSG00000136868 ENSG00000182511 ENSG00000198793 ENSG00000123191 ENSG00000161513 ENSG00000137714 PMC10377916__F2 Revisiting Estrogen for the Treatment of Endocrine-Resistant Breast Cancer: Novel Therapeutic Approaches ENSG00000291971 ENSG00000100219 ENSG00000168040 ENSG00000168610 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC7835541__F3 Effect of Maxing Shigan decoction against coronavirus disease 2019 (COVID-19) revealed by network pharmacology and experimental verification ENSG00000213928 ENSG00000154016 PMC4687794__F7 Signalling pathways downstream of CCK‐8s in pancreatic beta cells ENSG00000002330 ENSG00000163394 PMC6556479__F1 MC4R signaling pathway plays a vital role in regulating appetite and energy balance ENSG00000177551 ENSG00000174483 ENSG00000072364 ENSG00000138686 ENSG00000140463 ENSG00000122507 ENSG00000108557 ENSG00000163421 ENSG00000115138 ENSG00000175426 ENSG00000181004 ENSG00000288188 ENSG00000112246 ENSG00000116127 ENSG00000087460 ENSG00000135324 ENSG00000183395 ENSG00000177189 ENSG00000112210 ENSG00000178188 ENSG00000171435 ENSG00000198576 ENSG00000124089 ENSG00000179941 ENSG00000166603 ENSG00000125124 PMC3387006__F8 miRNA-mRNA Correlation-Network Modules in Human Prostate Cancer and the Differences between Primary and Metastatic Tumor Subtypes ENSG00000135446 ENSG00000133740 ENSG00000124762 PMC3387006__F7 miRNA-mRNA Correlation-Network Modules in Human Prostate Cancer and the Differences between Primary and Metastatic Tumor Subtypes ENSG00000049323 ENSG00000134363 ENSG00000133740 ENSG00000172201 ENSG00000137801 PMC8945680__F1 NFKB Signaling and Inflammation—Drug Repurposing to Treat Inflammatory Disorders? ENSG00000104856 ENSG00000186716 ENSG00000173039 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC4052840__F2 Therapeutics in development that target survival pathways activated by LMP1 and LMP2a ENSG00000010810 ENSG00000198793 PMC3409438__F2 Broad receptor antagonism and attenuation of downstream signaling cascades mediated by decorin in tumor cells ENSG00000100234 ENSG00000087245 ENSG00000136997 ENSG00000168036 ENSG00000112715 ENSG00000113302 ENSG00000124762 ENSG00000137801 PMC8073517__F1 Adaptor Protein Myeloid Differentiation 88 (MyD88) in Post-Subarachnoid Hemorrhage Inflammation: A Systematic Review ENSG00000172936 ENSG00000150455 ENSG00000175104 PMC4348149__F1 Signaling-mediated Regulation of MicroRNA Processing ENSG00000012048 ENSG00000083223 ENSG00000108654 ENSG00000124571 ENSG00000134744 ENSG00000146648 ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC12195072__F4 In the kidney and parathyroid glands, FGF23 signaling requires the presence of FGFR (fibroblast growth factor receptor) and the coreceptor klotho ENSG00000118972 ENSG00000152266 ENSG00000160867 PMC6371191__F5 Role of PAK signaling in response to inflammation, altered microbiota and hyperglycemia ENSG00000134982 ENSG00000149269 ENSG00000177606 ENSG00000173039 ENSG00000168036 ENSG00000136869 PMC9260738__F1 Hypoxia-inducible factor-1A: A critical target for inhibiting the metastasis of hepatocellular carcinoma ENSG00000134086 ENSG00000064393 PMC12255092__F1 Cholesterol structure and synthesis ENSG00000116133 ENSG00000172893 ENSG00000113161 PMC12255092__F6 Therapies that target lipid metabolism ENSG00000160179 PMC7016950__F8 Schematic outline representing neuronal adiponectin signaling pathway in the brain upon consumption of HFD ENSG00000150782 ENSG00000159346 ENSG00000131095 ENSG00000102003 ENSG00000167419 PMC7093169__F2 Molecular mechanisms driving renal fibrosis are wide-ranging and complex, among which signaling pathways are very important ENSG00000157500 ENSG00000086991 ENSG00000285070 PMC9318993__F7 Flightless I Negatively Regulates Macrophage Surface TLR4, Delays Early Inflammation, and Impedes Wound Healing ENSG00000284571 ENSG00000172936 ENSG00000136869 PMC6857536__F2 Role of Ras pathway proteins in exo-some biogenesis, cargo selection and release ENSG00000070831 ENSG00000138798 ENSG00000163914 ENSG00000185591 ENSG00000146648 PMC9513835__F7 Molecular Mechanisms of Spawning Habits for the Adaptive Radiation of Endemic East Asian Cyprinid Fishes ENSG00000070087 ENSG00000175899 ENSG00000284588 ENSG00000062485 PMC3776053__F7 A model for mid-day contrast sensitivity regulation ENSG00000164742 PMC4514180__F4 Signal transduction pathways drive cancer metastasis ENSG00000169291 ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000140443 PMC6830116__F4 Signaling pathways involved in Epithelial-to-Mesenchymal Transition ENSG00000019991 ENSG00000124216 ENSG00000070831 ENSG00000138798 ENSG00000170558 ENSG00000163914 ENSG00000150457 ENSG00000128602 ENSG00000168610 ENSG00000146648 ENSG00000131023 PMC4514180__F2 Roadmap of peptide vaccine versus peptide mimic strategies ENSG00000183691 PMC3355967__F1 Schematic of exosome secretion in a cancer cell model ENSG00000041353 ENSG00000144566 ENSG00000123595 PMC7039994__F7 Chromatin accessibility is associated with the changed expression of miRNAs that target members of the Hippo pathway during myoblast differentiation ENSG00000066468 ENSG00000070193 ENSG00000157764 ENSG00000108861 ENSG00000174233 ENSG00000291431 ENSG00000115904 ENSG00000155903 ENSG00000087460 ENSG00000133818 PMC4276927__F4 Three intracellular signaling pathways are shown schematically ENSG00000198793 ENSG00000169032 ENSG00000121879 ENSG00000196712 PMC11855151__F6 displays the chemokine signaling pathway with all top-ranking lncRNAs and their interaction with pathway genes ENSG00000084093 ENSG00000169291 ENSG00000002330 PMC11855151__F5 Antigen processing and presentation pathway (KEGG: 04612) displaying DE gene expression between AU and EU and the influence of the top-ranking lncRNAs in the prostate ENSG00000111537 ENSG00000163131 ENSG00000127022 ENSG00000273686 ENSG00000231925 PMC5819365__F1 Fanconi Anemia Signaling and Cancer ENSG00000149311 ENSG00000187790 ENSG00000078098 PMC11855151__F9 Antigen processing and presentation pathway (KEGG: 04612) displaying gene regulation of AF vs ENSG00000111537 ENSG00000127022 ENSG00000102786 ENSG00000231925 ENSG00000088926 ENSG00000079435 ENSG00000132639 PMC8867096__F2 Unraveling Muscle Impairment Associated With COVID-19 and the Role of 3D Culture in Its Investigation ENSG00000130234 ENSG00000132693 PMC8379503__F8 Impaired mitochondrial homeostasis and NAD+ metabolism in a model of mitochondrial heart disease exhibiting redox active iron accumulation ENSG00000105835 ENSG00000173614 ENSG00000096717 ENSG00000106459 PMC4496188__F10 The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1 ENSG00000291971 ENSG00000149269 ENSG00000138798 ENSG00000146648 PMC6671870__F6 The role of IDO/kynurenine in cancer immunoediting ENSG00000049768 PMC7327075__F1 Interaction between ferroptosis and lipid metabolism in cancer ENSG00000168003 ENSG00000135423 ENSG00000151012 ENSG00000196839 ENSG00000167468 ENSG00000111684 ENSG00000145321 ENSG00000167419 PMC6671870__F5 Sirtuins and epigenetic regulation of immune cell functions ENSG00000187531 ENSG00000136869 ENSG00000124523 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000089163 ENSG00000283100 PMC7534081__F1 Simplified schematic representation of the synthesis and metabolism of vitamin D.7-dehydrocholesterol in the skin is converted to previtamin D3 by UV-B and then is thermally isomerized to vitamin D3 ENSG00000111012 ENSG00000019186 ENSG00000186104 PMC7718039__F3 Mitochondria-mediated regulated cell death ENSG00000143799 ENSG00000137275 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC5722548__F1 CYP19A1 polymorphisms associated with coronary artery disease and circulating sex hormone levels in a Chinese population ENSG00000108786 ENSG00000196502 ENSG00000140505 ENSG00000140465 ENSG00000203857 PMC7039994__F4 Chromatin accessibility is associated with the changed expression of miRNAs that target members of the Hippo pathway during myoblast differentiation ENSG00000113645 ENSG00000004975 ENSG00000162552 ENSG00000122180 ENSG00000141551 ENSG00000101109 ENSG00000221914 ENSG00000174804 ENSG00000139926 ENSG00000018408 ENSG00000131023 ENSG00000186298 ENSG00000074219 ENSG00000068028 ENSG00000186575 ENSG00000115266 ENSG00000019549 PMC8742449__F5 Induction and application of ferroptosis in cancer therapy ENSG00000168003 ENSG00000159128 ENSG00000111537 ENSG00000151012 ENSG00000105329 ENSG00000115415 ENSG00000167468 ENSG00000027697 ENSG00000118520 ENSG00000168610 ENSG00000057663 PMC3768199__F1 Schematic overview of hippocampal signaling pathways following sleep deprivation ENSG00000164879 ENSG00000187531 ENSG00000102317 ENSG00000036672 ENSG00000162409 ENSG00000198793 ENSG00000111725 PMC2405914__F4 Catenins: Keeping Cells from Getting Their Signals Crossed ENSG00000070831 ENSG00000163914 ENSG00000168036 ENSG00000164690 PMC8051110__F10 Combination of RRM2 silencing and radiotherapy promotes the activation of cGAS/STING signaling pathway in LUAD cells ENSG00000169245 ENSG00000164430 ENSG00000171848 PMC5632571__F1 Transcriptional regulation of Th9 cell generation ENSG00000134982 ENSG00000156127 ENSG00000137265 ENSG00000107485 PMC6044872__F2 Biosynthetic pathway of O-glycans ENSG00000008513 ENSG00000070526 ENSG00000070731 ENSG00000151914 PMC8669353__F3 DNA methylation profile of liver of mice conceived by in vitro fertilization ENSG00000131473 ENSG00000171105 ENSG00000002330 ENSG00000110395 ENSG00000010810 ENSG00000106070 ENSG00000198793 ENSG00000220205 ENSG00000079435 PMC8533760__F1 ERK: A Double-Edged Sword in Cancer. ERK-Dependent Apoptosis as a Potential Therapeutic Strategy for Cancer ENSG00000138166 ENSG00000115415 ENSG00000185591 ENSG00000158050 ENSG00000164086 PMC8476258__F2 Association Analysis of LEP Signaling Pathway with Type 2 Diabetes Mellitus in Chinese Han Population from South China ENSG00000162409 ENSG00000132356 ENSG00000168610 ENSG00000115592 PMC3786574__F2 Molecular mechanisms of T cell co-stimulation and co-inhibition ENSG00000070831 ENSG00000163599 ENSG00000198793 PMC5520447__F8 The functions of miR-26a/b-Jagged/Notch axis in modulation of EMT and fibrosis PMC12210845__F6 Analysis of protein-protein interaction network of combined DEPs and DEPPs related to ABA signaling pathway under HS in nucleus (a) and in chloroplast (b) ENSG00000196839 ENSG00000135605 PMC8229348__F2 Description of the relationship in healthy longevity and aging-related disease: from gene to protein ENSG00000118972 ENSG00000042832 ENSG00000133116 ENSG00000167910 ENSG00000198793 ENSG00000136997 ENSG00000057663 PMC12183514__F1 Mechanism of estrogen improving brain function, regulating lipid metabolism and alleviating osteoporosis ENSG00000042832 PMC8099713__F2 Host innate immune sensing pathway targeted by coronavirus ENSG00000183735 ENSG00000088888 ENSG00000102900 ENSG00000185745 ENSG00000172936 ENSG00000276561 PMC4447342__F2 Causal Modeling of Cancer-Stromal Communication Identifies PAPPA as a Novel Stroma-Secreted Factor Activating NFKB Signaling in Hepatocellular Carcinoma ENSG00000213928 ENSG00000151693 ENSG00000132510 ENSG00000124762 ENSG00000012048 ENSG00000144802 ENSG00000198742 ENSG00000196923 ENSG00000108375 ENSG00000105810 ENSG00000023445 ENSG00000104689 ENSG00000122257 ENSG00000143878 ENSG00000027697 ENSG00000221869 ENSG00000154127 ENSG00000131941 ENSG00000136603 ENSG00000080031 ENSG00000110395 ENSG00000118503 ENSG00000172602 ENSG00000123609 ENSG00000134070 ENSG00000104856 ENSG00000128016 ENSG00000105329 ENSG00000120889 ENSG00000229314 ENSG00000089159 ENSG00000137801 ENSG00000109819 ENSG00000157557 ENSG00000011422 ENSG00000125968 ENSG00000100065 ENSG00000187678 ENSG00000100906 ENSG00000175793 ENSG00000285109 ENSG00000109320 ENSG00000125733 ENSG00000163874 ENSG00000107863 ENSG00000163435 ENSG00000107338 ENSG00000072401 ENSG00000177606 ENSG00000184371 PMC8099713__F1 Sensing of RNA virus invasion by RLRs and TLRs ENSG00000183735 ENSG00000088888 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC3263689__F2 VHL complex targets HIF-1A and HIF-2A for ubiquitin-mediated degradation ENSG00000134086 ENSG00000100387 ENSG00000163235 ENSG00000146648 PMC8099713__F3 Antagonizing IFN-mediated immune responses by coronavirus ENSG00000213928 ENSG00000187608 ENSG00000105397 ENSG00000144895 ENSG00000115415 ENSG00000276561 ENSG00000142166 PMC3263689__F5 FLCN pathway ENSG00000002330 ENSG00000052795 ENSG00000217128 PMC8224678__F1 Bovine Endometrial Cell Receptors and Signaling Pathways as a Nanotherapeutic Exploration against Dairy Cow Postpartum Endometritis ENSG00000162711 ENSG00000239732 ENSG00000150455 ENSG00000175104 ENSG00000164342 ENSG00000276068 PMC6722770__F3A Prebiotics: Mechanisms and Preventive Effects in Allergy ENSG00000108691 ENSG00000125538 ENSG00000198793 ENSG00000168610 PMC4631758__F3 Gene regulatory networks involved in photoreceptor development ENSG00000105392 ENSG00000119614 ENSG00000285493 ENSG00000168267 PMC11015775__F1 Treatment algorithms of relapsing multiple sclerosis: an exploration based on the available disease-modifying therapies in China ENSG00000163235 ENSG00000134982 PMC9479353__F5 Genetic regulation of RNA splicing in human pancreatic islets ENSG00000150594 ENSG00000108298 ENSG00000104408 ENSG00000065135 ENSG00000161016 ENSG00000163032 ENSG00000105640 ENSG00000184110 ENSG00000100353 ENSG00000091844 ENSG00000149100 ENSG00000160360 ENSG00000112306 PMC7371520__F2 Caspase-1-dependent and -independent pyroptosis ENSG00000278718 ENSG00000163568 ENSG00000125538 ENSG00000163914 PMC9552028__F1 Organoids as a Model System for Studying Notch Signaling in Intestinal Epithelial Homeostasis and Intestinal Cancer ENSG00000114315 ENSG00000137845 ENSG00000172238 PMC8709313__F2 TKI Era in Chronic Leukemias ENSG00000177455 ENSG00000095585 ENSG00000105369 ENSG00000007312 ENSG00000198793 ENSG00000197943 ENSG00000010671 PMC8709313__F1 TKI Era in Chronic Leukemias ENSG00000186716 ENSG00000177606 PMC7324530__F1 PI3K/Akt pathway in health (A), cancer (B) and AD brain (C) cells ENSG00000169047 ENSG00000100744 PMC8431328__F1 Influence of the Aryl Hydrocarbon Receptor Activating Environmental Pollutants on Autism Spectrum Disorder ENSG00000140505 ENSG00000140465 ENSG00000106546 PMC7441741__F3 Tumorigenic mechanism in somatotroph cells ENSG00000110711 ENSG00000291972 ENSG00000165370 ENSG00000010310 PMC3648157__F7 Dysregulation of cellular networks in the presence of PAN RNA expression ENSG00000162711 ENSG00000102962 ENSG00000125740 ENSG00000167207 ENSG00000187796 ENSG00000119508 ENSG00000122877 ENSG00000151929 ENSG00000162772 ENSG00000115718 ENSG00000064300 ENSG00000074181 ENSG00000160013 ENSG00000160182 ENSG00000089041 ENSG00000243509 ENSG00000274538 ENSG00000276561 ENSG00000277943 ENSG00000131015 ENSG00000163435 ENSG00000138378 ENSG00000138166 ENSG00000186716 ENSG00000028137 PMC5799368__F7 Model for the regulation of BMI1 on androgen receptor independently of PRC1 ENSG00000198901 ENSG00000184012 ENSG00000074266 PMC3764819__F4 Enrichment of the Notch signaling pathway in glioma CSCs ENSG00000168214 ENSG00000148400 ENSG00000074181 ENSG00000108773 ENSG00000273529 ENSG00000161202 ENSG00000178498 ENSG00000184916 ENSG00000168610 PMC7922135__F8 Hippo signaling pathway in OC (A) The main genes involved in Hippo signaling as regards OC and the associated miRNAs ENSG00000105327 ENSG00000078900 ENSG00000167074 ENSG00000150457 ENSG00000131023 PMC3957914__F5 IFN-Beta-mediated regulation of PI3K/Akt/mTOR signaling and pharmacological agents active in this pathway ENSG00000105397 ENSG00000169047 ENSG00000198793 ENSG00000167965 ENSG00000142166 PMC4302648__F4 Schematic plot of lncRNAs expressed in NSCLCs and their functions ENSG00000170558 ENSG00000136997 ENSG00000276920 PMC6330346__F3 Rapamycin inhibits the de-differentiation of vascular smooth muscle cells ENSG00000125538 ENSG00000198793 ENSG00000077782 PMC8832753__F2 B-cell maturation antigen targeting strategies in multiple myeloma treatment, advantages and disadvantages ENSG00000177455 ENSG00000095585 ENSG00000104856 ENSG00000124102 ENSG00000002330 ENSG00000197943 ENSG00000131323 ENSG00000127191 ENSG00000010671 PMC10770335__F3 Regulation mechanisms of KCC2 in mature neurons ENSG00000143867 ENSG00000124181 PMC8832753__F1 B-cell maturation antigen targeting strategies in multiple myeloma treatment, advantages and disadvantages ENSG00000173599 ENSG00000145321 PMC11001198__F6 Age-related changes after intracerebral hemorrhage: a comparative proteomics analysis of perihematomal tissue ENSG00000177575 ENSG00000155229 ENSG00000010704 ENSG00000138449 ENSG00000138798 ENSG00000178752 ENSG00000090674 ENSG00000072274 ENSG00000105697 ENSG00000211584 ENSG00000168610 ENSG00000166595 ENSG00000182511 ENSG00000060566 PMC11001198__F5 Age-related changes after intracerebral hemorrhage: a comparative proteomics analysis of perihematomal tissue ENSG00000177575 ENSG00000010704 ENSG00000138449 ENSG00000138798 ENSG00000178752 ENSG00000090674 ENSG00000072274 ENSG00000105697 ENSG00000146648 ENSG00000211584 ENSG00000130513 PMC6096230__F1 NOTCH signaling and graft-versus-host disease ENSG00000148400 ENSG00000184916 ENSG00000114315 PMC10308667__F2 Comprehensive insight into the correlation between ncRNAs and the Wnt/Beta-catenin signalling pathway in gastric cancer pathogenesis ENSG00000134982 ENSG00000168036 ENSG00000140807 PMC10308667__F1 Comprehensive insight into the correlation between ncRNAs and the Wnt/Beta-catenin signalling pathway in gastric cancer pathogenesis ENSG00000169071 ENSG00000134982 ENSG00000168036 PMC6096230__F2 Notch signaling in mesenchymal stem cells ENSG00000148400 ENSG00000049768 ENSG00000184916 ENSG00000114315 PMC10308667__F3 Comprehensive insight into the correlation between ncRNAs and the Wnt/Beta-catenin signalling pathway in gastric cancer pathogenesis ENSG00000154342 ENSG00000134982 ENSG00000155011 ENSG00000124766 ENSG00000058091 ENSG00000168036 ENSG00000125084 PMC8028134__F6 Pathway of flavonoid biosynthesis in the leaves of C ENSG00000180210 ENSG00000117525 PMC4077930__F3 mTORC2 in the center of cancer metabolic reprogramming ENSG00000067057 ENSG00000153574 ENSG00000115419 ENSG00000159399 PMC3070553__F11 Signaling modules identified by correlational analysis of end points ENSG00000002330 ENSG00000291971 ENSG00000168036 ENSG00000168610 ENSG00000146648 ENSG00000105723 PMC7949100__F1 Central role of AR signaling in prostate cancer and targets in CRPC ENSG00000125686 ENSG00000277273 PMC5794831__F1 KEGG NFKB Signalling Network with dysregulated mRNAs highlighted and their associated miRNAs included ENSG00000242689 ENSG00000102871 ENSG00000109654 ENSG00000111321 ENSG00000150455 ENSG00000166278 ENSG00000127191 ENSG00000010671 ENSG00000095585 ENSG00000149311 ENSG00000226275 ENSG00000213658 ENSG00000170458 ENSG00000186716 ENSG00000125538 ENSG00000136869 ENSG00000107201 ENSG00000131323 ENSG00000175104 PMC10121351__F8 Schematic of the molecular mechanism underlying UA anticancer activity in NSCLC cells ENSG00000138798 ENSG00000118777 ENSG00000168610 ENSG00000146648 PMC4124246__F1 Signaling pathway induced by malarial ligand during liver-stage infection ENSG00000175054 ENSG00000183735 ENSG00000088888 ENSG00000111537 ENSG00000172936 ENSG00000276561 PMC9654982__F1 Advancements on the Multifaceted Roles of Sphingolipids in Hematological Malignancies ENSG00000100422 ENSG00000147869 ENSG00000102172 PMC4150215__F7 CREB-dependent cell cycle factor expression signalling network in GBM tumour cells ENSG00000134057 ENSG00000132646 PMC10369979__F1 An oligonucleotide-based cGAS agonist for cancer immunotherapy ENSG00000164430 ENSG00000214285 PMC2879143__F4 Signaling cluster and integrin signaling ENSG00000157933 ENSG00000143839 ENSG00000146648 PMC4646463__F1 Dynamic Bayesian Network Modeling of the Interplay between EGFR and Hedgehog Signaling ENSG00000164161 ENSG00000109321 ENSG00000138798 ENSG00000198793 ENSG00000128602 ENSG00000146648 PMC5492466__F3 Transcriptional changes of genes involved in basic metabolism in Bgt during asexual development on Chancellor ENSG00000167113 ENSG00000047597 ENSG00000062485 PMC6693483__F2 Basic schematic representation of the cAMP-PKA pathway (green) and three MAPK pathways in Candida albicans which are important for morphogenesis, adaptation to stress and survival ENSG00000196511 ENSG00000070831 PMC7222375__F3 Main cell signaling pathway involved in red cell homeostasis PMC4568928__F1 Proposed model for multiple-target inhibitory action in TT cells ENSG00000157764 ENSG00000291971 ENSG00000198793 PMC10304357__F1 Targeting cGAS/STING signaling-mediated myeloid immune cell dysfunction in TIME ENSG00000164430 ENSG00000175104 PMC9490147__F5 DNA repair as a shared hallmark in cancer and ageing ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000138346 ENSG00000039650 ENSG00000137074 ENSG00000197299 ENSG00000051180 ENSG00000138375 ENSG00000136936 PMC8482189__F3 New Insights into the Biology and Diagnosis of Splenic Marginal Zone Lymphomas ENSG00000023445 ENSG00000118503 ENSG00000186716 ENSG00000127528 ENSG00000172936 ENSG00000131323 ENSG00000006062 ENSG00000100721 ENSG00000198286 PMC7412551__F3 K-bZIP inhibits antiviral innate immune signaling and anti-proliferative signaling ENSG00000183735 ENSG00000164430 ENSG00000123374 PMC8482189__F4 New Insights into the Biology and Diagnosis of Splenic Marginal Zone Lymphomas ENSG00000023445 ENSG00000118503 ENSG00000148400 ENSG00000127528 ENSG00000172936 ENSG00000131323 PMC1682015__F2 Example pathway structures based on Z-scores of reactions, which demonstrate the metabolomic response of the selected reactions in the reported case studies, namely, the effect of an altered redox metabolism and aerobic/anaerobic growth ENSG00000122966 ENSG00000124253 PMC2879143__F3 Activation of apoptotic signaling via caspase 3 and gelsolin ENSG00000134982 ENSG00000100813 ENSG00000067900 ENSG00000168522 PMC6039341__F3 RAS signaling cascade and EMT: Growth factors including EGF, FGF, HGF, VEGF, PDGF, IGF act through RTKs and activate PI3K–AKT, RAS-RAF-MEK-ERK MAPK and SRC signaling cascade ENSG00000169554 ENSG00000291971 ENSG00000138798 ENSG00000113140 ENSG00000132849 ENSG00000072415 PMC5732092__F2 Interleukin (IL)-17RA/RC signaling pathways ENSG00000082512 ENSG00000175104 ENSG00000127191 ENSG00000163702 PMC4538579__F1 BAFF-induced activation of NFKB signaling and increased expression of proinflammatory cytokines as procachectic mediators ENSG00000104856 ENSG00000082512 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC7606751__F1 Role of BCAA metabolism in cancer progression ENSG00000213658 ENSG00000291971 ENSG00000103507 ENSG00000163644 ENSG00000143995 PMC9600986__F2 Recent Advancements in Molecular Therapeutics for Corneal Scar Treatment ENSG00000100985 ENSG00000127948 PMC3504641__F1 Schema of the cholesterol pathway ENSG00000001630 ENSG00000116133 ENSG00000149809 ENSG00000104549 PMC5436279__F5 Several roles of scrapie responsive gene 1 (SCRG1) suggested in this study and our previous reports ENSG00000178860 ENSG00000102962 ENSG00000109743 ENSG00000170458 ENSG00000136869 PMC4215229__F6 A model of FGFR4-mediated metabolic regulations ENSG00000160867 ENSG00000105550 ENSG00000167910 PMC11967072__F5 miRNA-mRNA regulatory network analysis and screening of the hub miRNAs ENSG00000002330 ENSG00000198793 ENSG00000169047 ENSG00000213341 ENSG00000118971 ENSG00000177455 ENSG00000103479 ENSG00000073060 ENSG00000173757 ENSG00000186716 ENSG00000150907 ENSG00000026508 ENSG00000185591 ENSG00000105810 ENSG00000096717 ENSG00000139687 ENSG00000140443 ENSG00000109670 PMC5041020__F1 Leptin and jak-stat in cancer ENSG00000157554 ENSG00000019991 ENSG00000087245 ENSG00000105329 ENSG00000138798 ENSG00000198793 ENSG00000171791 ENSG00000112715 ENSG00000168610 ENSG00000291972 ENSG00000115415 ENSG00000136997 ENSG00000100985 ENSG00000139687 PMC3822800__F5 Diagram represents the molecular cross-talk between TLR2 heterodimers with TLR6/TLR1 and GR through the participation of PI3K ENSG00000174125 ENSG00000172936 ENSG00000150455 PMC2829067__F1 Caspase-1 Activation via Rho GTPases: A Common Theme in Mucosal Infections? ENSG00000167207 ENSG00000070831 ENSG00000163568 ENSG00000125538 PMC6125368__F2 Scheme of possible mechanisms by which autoimmune diseases are mediated by IGF-IGFBP signaling pathways ENSG00000169047 ENSG00000198793 PMC4177473__F1 S-adenosylmethionine is produced from methionine by methionine adenosyltransferase PMC9409318__F7 Multiplexed Human Gene Expression Analysis Reveals a Central Role of the TLR/mTOR/PPARG and NFkB Axes in Burn and Inhalation Injury-Induced Changes in Systemic Immunometabolism and Long-Term Patient Outcomes ENSG00000174125 ENSG00000177169 ENSG00000142192 ENSG00000187554 ENSG00000163914 ENSG00000136869 ENSG00000118520 ENSG00000186654 PMC3073847__F1 TGFB signaling pathway TGFB is secreted in a latent form and activation is mediated by several molecules including furin and emilin ENSG00000170365 ENSG00000140564 ENSG00000139567 ENSG00000138080 ENSG00000135341 PMC7226514__F2 “Prion diseases pathway” from the Kyoto Encyclopedia of Genes and Genomes (KEGG) database with genes significantly modulated in brain samples from ASD patients that have been color-coded from blue (downregulated) to red (upregulated) ENSG00000146909 PMC8389414__F5 LM pathway analysis highlights upregulation of AA-derived LM in non-survivors patients ENSG00000146469 ENSG00000148344 ENSG00000168765 PMC8389414__F2 LM pathway analysis identifies an upregulation in ALOX5 activity in patients with severe disease ENSG00000146469 ENSG00000148344 ENSG00000168765 PMC9681083__F9 Schematic for the plausible mechanisms by which PI3K pathway inhibition mediated the anti-leukemic activity of FD268 AML cells ENSG00000002330 ENSG00000198793 PMC4349374__F1 Molecular events in the autophagy pathway ENSG00000152348 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC11091328__F1 Regulatory mechanisms of SIRT1 on ER stress and NFKB signaling pathways ENSG00000128272 ENSG00000100219 ENSG00000096717 PMC8530467__F1 Does infection with or vaccination against SARS-CoV-2 lead to lasting immunity? ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000115415 ENSG00000130234 ENSG00000184012 ENSG00000106100 PMC4594309__F1 Neurogenic niches and Eph:ephrin signaling ENSG00000108702 ENSG00000116106 PMC4674750__F3 Infection with Mycobacterium tuberculosis induces the Warburg effect in mouse lungs ENSG00000180210 ENSG00000074800 ENSG00000067057 ENSG00000159399 PMC7269991__F1 SOCS family genes were re-analyzed by KEGG pathway enrichment ENSG00000213928 ENSG00000198793 ENSG00000137193 ENSG00000131095 PMC3335938__F1 Key therapeutic targets in the PI3K/Akt and MAPK pathways together with pharmacological agents inhibiting members of these signaling cascades ENSG00000124102 ENSG00000117020 ENSG00000002330 ENSG00000198793 PMC7910854__F8 Schematics of neural circuit involved in phototaxis behavior ENSG00000104321 ENSG00000258429 PMC3727154__F1 Immunomodulatory functions of type I interferons ENSG00000159128 ENSG00000213928 ENSG00000138378 ENSG00000111537 ENSG00000105397 ENSG00000198793 ENSG00000027697 ENSG00000168610 ENSG00000073861 ENSG00000142166 PMC2697290__F1 Phenomics of cardiac chloride channels: the systematic study of chloride channel function in the heart ENSG00000016490 ENSG00000001626 PMC4292735__F1 Insulin growth factor 1 (IGF-1) signaling pathway ENSG00000002330 ENSG00000198793 ENSG00000169047 ENSG00000155792 ENSG00000164327 ENSG00000140443 PMC4943968__F5 KEGG pathway (pathways in cancer) analysis with predicated target genes from all selected differentially expressed miRNAs ENSG00000145604 ENSG00000108055 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000205250 ENSG00000277273 ENSG00000117399 ENSG00000276876 ENSG00000093009 PMC9385303__F10 Network Pharmacology Analysis, Molecular Docking, and In Vitro Verification Reveal the Action Mechanism of Prunella vulgaris L. in Treating Breast Cancer ENSG00000142192 ENSG00000102871 ENSG00000026103 PMC7884707__F4 Wnt/Beta-Catenin signaling pathway-mediated therapy resistance in CSCs ENSG00000281324 ENSG00000162337 ENSG00000005513 ENSG00000134982 ENSG00000112562 ENSG00000026508 ENSG00000168036 ENSG00000125968 PMC7884707__F3 Hedgehog (Hh) signaling pathway-mediated therapy resistance in CSCs ENSG00000106571 ENSG00000164690 PMC3243341__F3 Conversion of major constituents in the stem cuticular wax biosynthetic pathway ENSG00000166278 ENSG00000062485 PMC7744569__F4 Summary of metabolic engineering performed to increase fatty alcohol production in S ENSG00000157911 ENSG00000128513 PMC7769624__F10 Development of a hybrid model for a partially known intracellular signaling pathway through correction term estimation and neural network modeling ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC5063567__F2 The Kynurenine Pathway Is a Double-Edged Sword in Immune-Privileged Sites and in Cancer: Implications for Immunotherapy ENSG00000167074 ENSG00000106546 PMC12029365__F4 TME lactate signaling ENSG00000184254 ENSG00000109321 ENSG00000198793 ENSG00000183484 PMC4943968__F4 KEGG pathway (pathways in cancer) analysis with predicated target genes from downregulated miRNAs ENSG00000145604 ENSG00000094804 ENSG00000132646 ENSG00000135336 ENSG00000123374 ENSG00000164754 ENSG00000205250 ENSG00000277273 ENSG00000276876 ENSG00000093009 PMC4943968__F3 KEGG pathway (pathways in cancer) analysis with predicated target genes from upregulated miRNAs ENSG00000145604 ENSG00000108055 ENSG00000132646 ENSG00000135336 ENSG00000123374 ENSG00000205250 ENSG00000277273 ENSG00000166851 ENSG00000276876 ENSG00000093009 PMC8294037__F2 Functional Polymorphisms in the p53 Pathway Genes on the Genetic Susceptibility to Zika Virus Teratogenesis ENSG00000042832 ENSG00000145321 ENSG00000128342 PMC4382528__F2 Metabolic pathway of rotigotine ENSG00000165841 ENSG00000196620 ENSG00000140465 PMC5630306__F7 Lyn mediates FIP1L1-PDGFRA signal pathway facilitating IL-5RA intracellular signal through FIP1L1-PDGFRA/JAK2/Lyn/Akt network complex in CEL ENSG00000197971 ENSG00000113525 PMC3238353__F2 Crosstalk between UPR signalling pathways and lipogenesis ENSG00000128272 ENSG00000144895 ENSG00000186480 PMC7941261__F5 Skeletogenic cell gene regulatory network (GRN) ENSG00000157554 ENSG00000167074 ENSG00000170802 PMC3238353__F1 ER stress and activation of the UPR signalling pathways ENSG00000128272 PMC10388482__F9 SALL4 promotes angiogenesis in gastric cancer by regulating VEGF expression and targeting SALL4/VEGF pathway inhibits cancer progression ENSG00000112715 ENSG00000150630 PMC3681689__F6 Working model for the roles of the mitochondrial chaperones Ssq1-Jac1 and the glutaredoxin Grx5 in Fe/S protein maturation in eukaryotes ENSG00000169599 PMC6123662__F2 Brown adipocyte glucose metabolism: a heated subject ENSG00000104812 ENSG00000151726 ENSG00000042832 ENSG00000111713 ENSG00000103569 ENSG00000169710 ENSG00000165269 ENSG00000062282 ENSG00000102977 ENSG00000173599 ENSG00000124253 ENSG00000159399 ENSG00000060762 ENSG00000062485 PMC3644409__F7 Proposed model showing molecular mechanisms of dysregulated immune pathways in diabetic renal tissues ENSG00000145824 ENSG00000232326 ENSG00000007908 ENSG00000285250 ENSG00000145777 ENSG00000185187 ENSG00000175567 ENSG00000168610 ENSG00000211445 ENSG00000224320 ENSG00000172216 ENSG00000113520 ENSG00000136869 ENSG00000175104 ENSG00000135517 PMC5369916__F4 Summary of detected genes associated with the MTX toxicity in RA patients in previous studies ENSG00000228716 ENSG00000118596 ENSG00000116748 ENSG00000136877 ENSG00000196839 ENSG00000103222 ENSG00000124275 ENSG00000035928 ENSG00000137563 ENSG00000118777 ENSG00000023839 ENSG00000076351 PMC2786873__F9 Model of amino acid starvation-induced AARE-dependent transcription in human cells ENSG00000128272 ENSG00000070831 ENSG00000144895 ENSG00000162772 PMC7157599__F2 An overview of intracellular signaling pathway regulation by the HECT E3 ubiquitin ligases ENSG00000069869 ENSG00000103657 ENSG00000078747 ENSG00000104517 ENSG00000198742 ENSG00000136997 ENSG00000086758 ENSG00000148634 ENSG00000123124 PMC8350904__EV4 Schematic depiction of the metabolic networks active during latent HIV‐1 infection in microglial cells ENSG00000131473 ENSG00000262785 ENSG00000074800 ENSG00000073578 ENSG00000049239 ENSG00000153574 ENSG00000226784 ENSG00000124253 ENSG00000166800 PMC7953519__F7 Novel compound variants of the AR and MAP3K1 genes are related to the clinical heterogeneity of androgen insensitivity syndrome ENSG00000125398 ENSG00000095015 ENSG00000168036 PMC2719801__F3 Gene Expression in Skeletal Muscle Biopsies from People with Type 2 Diabetes and Relatives: Differential Regulation of Insulin Signaling Pathways ENSG00000169967 ENSG00000171105 ENSG00000011566 ENSG00000162409 ENSG00000288174 ENSG00000136111 ENSG00000108443 ENSG00000121879 ENSG00000135341 ENSG00000100485 ENSG00000179295 PMC2719801__F2 Gene Expression in Skeletal Muscle Biopsies from People with Type 2 Diabetes and Relatives: Differential Regulation of Insulin Signaling Pathways ENSG00000104812 ENSG00000140992 ENSG00000104365 ENSG00000171105 ENSG00000065675 ENSG00000288174 ENSG00000141639 ENSG00000142273 ENSG00000121879 ENSG00000179295 ENSG00000107263 ENSG00000141503 ENSG00000220205 ENSG00000188130 ENSG00000079435 ENSG00000171608 PMC7600158__F1 MicroRNA (miRNA)-mediated modulating response to gemcitabine ENSG00000186575 ENSG00000291971 ENSG00000134982 ENSG00000168036 ENSG00000128342 ENSG00000168610 ENSG00000165795 PMC12237979__F2 Necroptotic pathways ENSG00000124256 ENSG00000102871 ENSG00000136869 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 ENSG00000164342 ENSG00000026103 PMC2517664__F2 A simplified diagram of the key type-1 cytokine/receptor interactions relevant for immunity against intracellular bacteria, derived from published gene knockout mouse studies ENSG00000096996 ENSG00000159128 ENSG00000111537 ENSG00000027697 PMC6345051__F5 Visual representation of molecular interactions in the TSF flock ENSG00000110492 ENSG00000184232 ENSG00000183844 ENSG00000169783 ENSG00000153064 ENSG00000007866 ENSG00000182985 ENSG00000134871 ENSG00000087303 ENSG00000116962 ENSG00000169116 ENSG00000115290 ENSG00000159556 ENSG00000092096 ENSG00000144857 ENSG00000090530 ENSG00000132819 ENSG00000187955 ENSG00000188783 ENSG00000182253 PMC3410677__F9 Schematic representation of potential interaction between the Rho GTPase signaling pathway, CTGF, and NMU in regulation of actomyosin-based contractile force and ECM protein profiles in TM cells ENSG00000163914 PMC6345051__F4 Visual representation of molecular interactions in the HSF flock ENSG00000177455 ENSG00000102962 ENSG00000162894 ENSG00000132465 ENSG00000105369 ENSG00000007312 ENSG00000104921 ENSG00000117322 PMC3798767__F5 p53 regulated developmental pathways ENSG00000162889 ENSG00000047410 ENSG00000142192 ENSG00000156076 ENSG00000134982 ENSG00000111837 ENSG00000133961 ENSG00000104332 PMC9097798__F1 Development of novel agents for the treatment of early estrogen receptor positive breast cancer ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC2679052__F7 Diagram summarizing differences in expression of interaction genes enriched within the KEGG p53 signaling pathway, and possible interactions of corresponding proteins with the androgen receptor ENSG00000124762 PMC4298213__F1 Generalized central metabolic pathway adapted and modified from a previous study ENSG00000125166 ENSG00000173599 ENSG00000213614 ENSG00000118094 ENSG00000146701 PMC5359264__F3 ReactomeFIViz: from disease pathway to PPI network ENSG00000105722 ENSG00000112242 ENSG00000150991 ENSG00000198176 ENSG00000185591 ENSG00000282899 PMC7553876__F1 Hypothetical mechanism by which SARS-CoV-2 successfully evade the immune system while maintaining an inflammatory feedback loop ENSG00000130234 ENSG00000125538 ENSG00000184012 PMC9546682__F7 Yangxin Tongmai Decoction in the Treatment of Coronary Heart Disease with Blood Stasis Syndrome Based on Network Pharmacology and Molecular Docking ENSG00000105664 ENSG00000142192 ENSG00000002330 ENSG00000069482 ENSG00000101440 ENSG00000198793 ENSG00000136997 PMC10931763__F8 “Component–gene–pathway” network ENSG00000182578 ENSG00000173083 ENSG00000112715 ENSG00000135914 ENSG00000121879 ENSG00000073756 ENSG00000122194 ENSG00000168610 ENSG00000164305 ENSG00000102468 ENSG00000149295 ENSG00000132170 ENSG00000184845 ENSG00000177606 ENSG00000164362 ENSG00000170989 ENSG00000100985 ENSG00000077782 ENSG00000196689 ENSG00000139687 ENSG00000115232 ENSG00000146648 ENSG00000113448 ENSG00000140443 PMC9942259__F7 LAPTM5 regulated by FOXP3 promotes the malignant phenotypes of breast cancer through activating the Wnt/B‑catenin pathway ENSG00000087245 ENSG00000170558 ENSG00000100985 ENSG00000049768 PMC8105340__F9 Endovascular progenitors cell fate ENSG00000125398 ENSG00000168214 ENSG00000134853 ENSG00000174059 ENSG00000114315 PMC8102455__F2 Fabry Disease: The Current Treatment Landscape ENSG00000170266 ENSG00000213614 PMC4367559__F2 Mechanisms of resistance due to MET/HGF pathway and potential interventional strategies ENSG00000019991 ENSG00000138798 ENSG00000112715 ENSG00000146648 PMC6162868__F1 Signaling pathways of high-risk HPV oncogenes ENSG00000135446 PMC4367559__F1 MET/HGF signaling and functional cross-talk with other pathways ENSG00000019991 ENSG00000169291 ENSG00000002330 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000112715 ENSG00000146648 PMC8955100__F1 Expression Profile and Biological Role of Immune Checkpoints in Disease Progression of HIV/SIV Infection ENSG00000089692 ENSG00000291603 ENSG00000117091 ENSG00000181847 PMC11241432__F3 MyD88-independent signaling pathway ENSG00000172005 ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000184216 PMC5693225__F6 RPL23 links oncogenic RAS signaling to p53-mediated tumor suppression ENSG00000125691 ENSG00000198793 PMC5779689__F2 Convergence of miR-143 overexpression, oxidative stress and cell death in HCT116 human colon cancer cells ENSG00000168028 ENSG00000182718 ENSG00000099901 ENSG00000074800 ENSG00000104969 ENSG00000132646 ENSG00000119608 ENSG00000120438 ENSG00000002549 ENSG00000170515 ENSG00000092820 ENSG00000161960 PMC6154708__F5 Epigenetic mechanisms of nanotopography-guided osteogenic differentiation of mesenchymal stem cells via high-throughput transcriptome sequencing ENSG00000124102 ENSG00000116176 ENSG00000162711 ENSG00000135636 ENSG00000147437 ENSG00000130528 ENSG00000167749 ENSG00000158578 ENSG00000070404 ENSG00000084110 ENSG00000165269 ENSG00000197769 ENSG00000292348 ENSG00000164309 ENSG00000112812 ENSG00000169688 ENSG00000086159 ENSG00000162438 ENSG00000143196 ENSG00000086730 PMC5730046__F3 Human iPSCs harbor homoplasmic and heteroplasmic mitochondrial DNA mutations while maintaining hESC-like metabolic reprogramming ENSG00000262785 ENSG00000065833 ENSG00000197713 ENSG00000160883 ENSG00000151229 ENSG00000173599 ENSG00000153574 ENSG00000105953 ENSG00000164708 ENSG00000132356 ENSG00000146701 PMC6086774__F1 Lipid metabolism in tumor cells ENSG00000131473 ENSG00000151726 ENSG00000135218 ENSG00000042832 ENSG00000169710 PMC6029376__F7 Working model of the mechanistic interaction of miR-335-5p and CPNE1 in the control of the EGFR signaling pathway: miR-335-5p regulates CPNE1 expression via EGFR signaling in NSCLC ENSG00000214078 ENSG00000291971 ENSG00000138798 ENSG00000170558 ENSG00000100985 PMC7139634__F6 Most common target genes and mTOR pathway regulated by the differentially expressed exosomal miRNAs ENSG00000140992 ENSG00000171105 ENSG00000198793 ENSG00000187840 ENSG00000089159 PMC7913176__F4 Degree Adjusted Large-Scale Network Analysis Reveals Novel Putative Metabolic Disease Genes ENSG00000112038 ENSG00000090316 ENSG00000167601 ENSG00000142192 ENSG00000143476 ENSG00000131747 ENSG00000203760 ENSG00000010017 ENSG00000146648 ENSG00000291944 PMC7465132__F2 Cell death receptor-associated signaling pathway ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 PMC7795579__F1 Inflammation-Induced Protein Unfolding in Airway Smooth Muscle Triggers a Homeostatic Response in Mitochondria ENSG00000116688 ENSG00000156026 PMC7984080__F1 Brain death‐induced lung injury is complement dependent, with a primary role for the classical/lectin pathway ENSG00000039537 ENSG00000113600 PMC3281591__F4 Mitochondrial-dependent apoptosis ENSG00000132906 ENSG00000171791 PMC6961632__F1 Unique Features of Nodules.(A) Nod factor activation of the CSSP ENSG00000070444 ENSG00000134398 ENSG00000080166 ENSG00000157005 PMC5653517__F1 Resistance to BRAF inhibitors can occur through stromal extracellular signals (blue) leading to ERK reactivation upstream of MEK (orange) or to enhanced survival signaling(green) ENSG00000157764 ENSG00000065361 ENSG00000146648 ENSG00000196712 ENSG00000140443 PMC8784536__F2 Immunomodulatory effects and mechanisms of distraction osteogenesis PMC7710763__F1 Interaction between gut microbiota, immune system and tryptophan metabolism in brain tumor development ENSG00000115902 ENSG00000128272 ENSG00000151012 ENSG00000115415 ENSG00000138798 ENSG00000125538 ENSG00000106546 PMC5390343__F6 Regulation of Fn expression in macrophages after S ENSG00000170458 ENSG00000291971 ENSG00000172936 ENSG00000175104 PMC2886982__F3 Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes ENSG00000026103 PMC8584042__F2 Mechanotransduction at the Plasma Membrane-Cytoskeleton Interface ENSG00000291971 ENSG00000163914 ENSG00000150457 ENSG00000131023 ENSG00000103335 PMC9485670__F2 Advances in the research of the mechanism of secondary resistance to imatinib in gastrointestinal stromal tumors ENSG00000140443 PMC7679160__F8 PPM1G restricts innate immune signaling mediated by STING and MAVS and is hijacked by KSHV for immune evasion ENSG00000183735 ENSG00000088888 PMC8037620__F1 Spectrum of changes in a senescent cell ENSG00000143799 ENSG00000198793 ENSG00000112715 ENSG00000115457 ENSG00000149968 ENSG00000141753 ENSG00000108688 ENSG00000189403 ENSG00000164400 ENSG00000123374 ENSG00000026103 ENSG00000262406 ENSG00000081041 ENSG00000115008 ENSG00000285109 ENSG00000109320 ENSG00000197632 ENSG00000108342 ENSG00000125347 ENSG00000108691 ENSG00000111537 ENSG00000108700 ENSG00000184371 ENSG00000100985 ENSG00000162692 PMC4217731__F7 Rho-Kinase Inhibition Ameliorates Metabolic Disorders through Activation of AMPK Pathway in Mice ENSG00000109819 ENSG00000131143 PMC6487791__F3 Therapeutic strategies targeting mutant p53 ENSG00000149311 ENSG00000135655 ENSG00000175054 ENSG00000124762 PMC6487791__F2 Representative working modes of mutant p53 GOF ENSG00000127445 ENSG00000151012 ENSG00000135446 PMC5915168__F1 MIF signaling pathway and its role in tumorigenesis ENSG00000019582 ENSG00000291971 ENSG00000026508 PMC5514692__F7 Dietary hemoglobin rescues young piglets from severe iron deficiency anemia: Duodenal expression profile of genes involved in heme iron absorption ENSG00000089472 ENSG00000156273 PMC2840235__F1 Blockade of the VEGF pathway with mAbs ENSG00000112715 ENSG00000150630 PMC12108901__F7 Comprehensive model of nitrogen and phosphorus interaction at different levels ENSG00000177971 PMC5053787__F1 Complement cascade ENSG00000288512 ENSG00000182326 ENSG00000236625 PMC9658871__F8 Exosome Secretion and Epithelial-Mesenchymal Transition in Ovarian Cancer Are Regulated by Phospholipase D ENSG00000129219 ENSG00000133110 PMC4648367__F7 Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway targetgenes and promote cell migration ENSG00000138798 ENSG00000198670 ENSG00000146648 ENSG00000131023 ENSG00000178568 PMC7783759__F7 Cezanne deubiquitinated IGF-1R and regulated IGF-1R signaling pathways ENSG00000169047 ENSG00000140443 PMC9368778__F5 Computational Analysis of Short Linear Motifs in the Spike Protein of SARS-CoV-2 Variants Provides Possible Clues into the Immune Hijack and Evasion Mechanisms of Omicron Variant ENSG00000183735 ENSG00000164430 ENSG00000150457 ENSG00000131023 PMC2807212__F3 TGFB superfamily and FGF signaling pathways ENSG00000137834 PMC10255413__F2 Biosynthetic pathway of chlorophyll ENSG00000080819 ENSG00000111341 ENSG00000127948 PMC8536449__F9 GNG4 Promotes Tumor Progression in Colorectal Cancer ENSG00000177455 ENSG00000124102 ENSG00000139610 ENSG00000115956 ENSG00000002330 ENSG00000069482 ENSG00000198793 ENSG00000136997 PMC2807212__F2 Hh and Wnt signaling pathways ENSG00000134982 ENSG00000168036 ENSG00000128602 PMC8507869__F3 Molecular Mechanism of EGFR-TKI Resistance in EGFR-Mutated Non-Small Cell Lung Cancer: Application to Biological Diagnostic and Monitoring ENSG00000167601 ENSG00000157764 ENSG00000135446 ENSG00000198793 ENSG00000047936 ENSG00000118971 ENSG00000146648 ENSG00000139687 PMC9268608__F11 Stereoselective Binding of Trans-(±)-Kusunokinin and Cis-(±)-Kusunokinin Isomers to CSF1R ENSG00000182578 ENSG00000157368 ENSG00000138798 ENSG00000184371 ENSG00000123374 ENSG00000085662 ENSG00000105639 ENSG00000168610 ENSG00000146648 PMC3514894__F1 Interplay between Smoking-induced Genotoxicity and Altered Signaling in Pancreatic Carcinogenesis ENSG00000138798 ENSG00000170558 ENSG00000177606 ENSG00000136997 ENSG00000145321 ENSG00000171759 ENSG00000171791 ENSG00000100985 ENSG00000139880 ENSG00000168610 ENSG00000146648 PMC5292191__F2 Extrinsic and intrinsic pathways of apoptosis ENSG00000168040 ENSG00000026103 PMC5292191__F1 TGFB signaling pathways ENSG00000159224 ENSG00000169291 ENSG00000291971 ENSG00000113140 ENSG00000163914 PMC4572424__F2 Effect of purple corn anthocyanins (PCA) on CCN2 expression ENSG00000115415 ENSG00000168610 PMC4156078__F7 Schematic diagram depicting the proposed role of miR-130a in BMP-SMAD signaling and hepcidin regulation under iron-deficient conditions ENSG00000170365 PMC8123809__F1 Effect of Space Travel on Bone Metabolism: Considerations on Today’s Major Challenges and Advances in Pharmacology ENSG00000168036 PMC9631428__F1 Research progress on microRNA in gout ENSG00000162711 ENSG00000169554 ENSG00000142627 ENSG00000172936 ENSG00000175104 PMC5684415__F1 Highest confidence network of genes significantly dysregulated by miR-7 ENSG00000137807 ENSG00000137834 ENSG00000134057 ENSG00000109805 ENSG00000171848 ENSG00000087586 ENSG00000138160 ENSG00000071539 ENSG00000117399 ENSG00000134690 ENSG00000144959 PMC5824027__F3 Hippo Pathway in Cancer Stem Cell Biology ENSG00000291971 ENSG00000134982 ENSG00000144560 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC5078657__F2 Cancer pathway targets affected by curcumin ENSG00000012061 ENSG00000134057 ENSG00000198793 ENSG00000004897 ENSG00000164690 ENSG00000112715 ENSG00000118777 ENSG00000168610 ENSG00000146648 ENSG00000121966 PMC3650722__F3 Network was generated using Ingenuity Pathway Analysis (Ingenuity Systems, www.ingenuity.com) ENSG00000170962 ENSG00000107798 ENSG00000134243 PMC9587083__F7 Hyaluronan-related genes HAS2, HYAL1-4, PH20 and HYALP1 are associated with prognosis, cell viability and spheroid formation capacity in ovarian cancer ENSG00000072571 ENSG00000170961 ENSG00000186792 ENSG00000038427 ENSG00000106302 ENSG00000276286 ENSG00000127415 ENSG00000026508 ENSG00000068001 ENSG00000169919 PMC5824027__F1 Hippo Pathway in Cancer Stem Cell Biology ENSG00000109321 ENSG00000144560 ENSG00000150457 ENSG00000131023 PMC4660682__F5 Relative functions and pathways in DN ENSG00000108679 ENSG00000138798 ENSG00000105697 ENSG00000184371 ENSG00000010278 ENSG00000158874 ENSG00000132693 PMC5039640__F6 Unravelling molecular mechanisms from floral initiation to lipid biosynthesis in a promising biofuel tree species, Pongamia pinnata using transcriptome analysis ENSG00000198670 ENSG00000102977 PMC3193279__F1 VEGF Signaling Pathway within endothelial cells ENSG00000100234 ENSG00000128052 ENSG00000115904 ENSG00000196396 PMC10367548__F8 The mechanism by purinergic receptor P2Y12 drives ConA-mediated autoimmune hepatitis through hexokinase 2-dependent glycolysis pathway ENSG00000111537 ENSG00000159399 PMC6889474__F3 mTOR Signaling Pathway ENSG00000284161 ENSG00000118515 ENSG00000187778 PMC6729444__F7 p35/Cdk5 involvement in RasGRF2 signaling ENSG00000138798 ENSG00000146648 PMC5037594__F7 Signaling pathways in EGF-induced AREG mRNA expression ENSG00000109321 ENSG00000138798 ENSG00000146648 PMC3722917__F3 Naive CD8+ T cells differentiate into cytotoxic T lymphocytes (CTLs) on exposure to antigens ENSG00000134982 PMC11040418__F2 Network pharmacological analysis of chondrocyte apoptosis modulation by RJNTF ENSG00000143799 ENSG00000094631 ENSG00000291931 ENSG00000044090 ENSG00000166402 ENSG00000170606 ENSG00000151929 ENSG00000073111 ENSG00000134086 ENSG00000136997 ENSG00000149273 ENSG00000142192 ENSG00000111530 ENSG00000285246 ENSG00000007908 ENSG00000063244 ENSG00000125347 ENSG00000007171 ENSG00000169245 ENSG00000127445 ENSG00000121481 ENSG00000139842 ENSG00000175104 ENSG00000162692 ENSG00000096717 ENSG00000146648 ENSG00000291971 ENSG00000182944 ENSG00000095015 ENSG00000196591 ENSG00000165280 ENSG00000087586 ENSG00000129351 ENSG00000089159 ENSG00000150991 ENSG00000263528 ENSG00000125538 ENSG00000132383 ENSG00000123374 ENSG00000100603 ENSG00000081041 ENSG00000100906 ENSG00000109320 ENSG00000173039 ENSG00000073756 ENSG00000070756 ENSG00000108691 ENSG00000141480 ENSG00000177606 ENSG00000115232 ENSG00000096401 ENSG00000141367 PMC8209426__F10 An Integrated Analysis of the Response of Colorectal Adenocarcinoma Caco-2 Cells to X-Ray Exposure ENSG00000149311 ENSG00000276876 PMC7584388__F5 Mechanisms underlying T cell ageing ENSG00000291603 ENSG00000164430 ENSG00000213658 ENSG00000285109 ENSG00000198793 PMC8428233__F2 Thyroid Hormone Receptor Beta as Tumor Suppressor: Untapped Potential in Treatment and Diagnostics in Solid Tumors ENSG00000115415 ENSG00000136997 ENSG00000272398 ENSG00000168610 PMC7906381__F2 Pathway enrichment analysis of (a) DE-miRNAs and (b) DCGs ENSG00000157404 ENSG00000006451 ENSG00000198793 PMC9593040__F2 Mitophagy in the aging nervous system ENSG00000158828 PMC3337681__F7 Putative inhibitory pathway of inflammatory signaling events by CA ENSG00000291971 ENSG00000136869 ENSG00000184216 PMC11939404__F9 Proposed mechanism of action of GAD037 ENSG00000171105 ENSG00000144857 ENSG00000130402 PMC9025382__F6 RNA-Seq of Cyst Nematode Infestation of Potato (Solanum tuberosum L.): A Comparative Transcriptome Analysis of Resistant and Susceptible Cultivars ENSG00000105722 PMC8340210__F2 Development of PARP inhibitor combinations for castration resistant prostate cancer unselected for homologous recombination repair mutations ENSG00000291803 ENSG00000129514 PMC11013310__F6 Our results are summarized in this diagram ENSG00000019991 ENSG00000132646 ENSG00000168036 PMC2390572__F9 MCF10A Pathway 1 affected by TFIIS knockdown ENSG00000198830 ENSG00000095739 ENSG00000087074 ENSG00000136997 ENSG00000013588 ENSG00000107281 ENSG00000172543 ENSG00000164136 ENSG00000136327 ENSG00000112378 ENSG00000106829 PMC2390572__F8 Major pathways affected by TFIIS knockdown in MCF7 ENSG00000131469 ENSG00000274700 ENSG00000136942 ENSG00000206075 ENSG00000125691 ENSG00000137947 ENSG00000063177 ENSG00000049130 ENSG00000134365 ENSG00000136997 ENSG00000139613 ENSG00000118257 ENSG00000184216 ENSG00000117475 ENSG00000127616 ENSG00000130827 PMC5325772__F4 Summary of relationship between B-catenin, MEN1, and NCOR1 mutations and the Wnt signaling pathway that upregulates aerobic glycosylation ENSG00000133895 ENSG00000168036 PMC8303858__F4 Bioinformatics Analysis of Allele Frequencies and Expression Patterns of ACE2, TMPRSS2 and FURIN in Different Populations and Susceptibility to SARS-CoV-2 ENSG00000118972 ENSG00000087245 ENSG00000140564 ENSG00000288174 ENSG00000143839 ENSG00000112715 ENSG00000137845 ENSG00000171388 ENSG00000120937 ENSG00000111537 ENSG00000130234 ENSG00000184012 ENSG00000100985 PMC3765220__F4 Pathway Studio analysis of the differentially expressed proteins of extremely severe HFMD serum samples. Proteins identified in Table  were imported into PathwayAssist and an interaction map was created ENSG00000012048 ENSG00000135437 ENSG00000116745 ENSG00000138207 ENSG00000167768 ENSG00000151655 ENSG00000175899 ENSG00000140464 PMC7349719__F2 GH/IGF on the Aging Mitochondria ENSG00000112964 ENSG00000140443 ENSG00000062485 PMC3046063__F7 Proposed working model and protein–protein interaction map ENSG00000143799 ENSG00000166579 ENSG00000124102 ENSG00000152348 ENSG00000198382 ENSG00000198793 ENSG00000127955 ENSG00000171791 ENSG00000057663 ENSG00000065135 ENSG00000138778 ENSG00000188554 ENSG00000163625 ENSG00000280610 ENSG00000144848 ENSG00000188487 ENSG00000146648 PMC5963164__F7 Prostate cancer pathway enriched in KEGG ENSG00000002330 ENSG00000198793 ENSG00000123374 ENSG00000171791 ENSG00000111816 PMC5963164__F8 ERK/MAPK signaling enriched in IPA ENSG00000172680 ENSG00000002330 ENSG00000291971 ENSG00000010810 ENSG00000173599 ENSG00000123268 ENSG00000089159 PMC7349719__F6 GH/IGF on the Aging Mitochondria ENSG00000100290 ENSG00000002330 ENSG00000171791 ENSG00000135116 ENSG00000104081 ENSG00000140443 PMC12256062__F8 Antagonists of cGAS-STING pathway for liver diseases therapy ENSG00000162711 ENSG00000183735 ENSG00000164430 ENSG00000100219 PMC6581679__F1 Canonical activation of HH-GLI signaling ENSG00000106571 ENSG00000128602 PMC6409748__F2 TLR-7/-8 signaling in dendritic cells ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC6581679__F3 Non-canonical activation of HH-GLI signaling by oncogenic pathways ENSG00000141867 ENSG00000157540 ENSG00000125398 ENSG00000198793 ENSG00000133961 ENSG00000146648 ENSG00000127334 ENSG00000105204 PMC1087583__F5 The secretory pathway and UPR under different conditions ENSG00000006715 PMC3502714__F3 Fibroblast growth factor 23: State of the field and future directions ENSG00000118972 ENSG00000140564 ENSG00000160867 ENSG00000115339 PMC3502714__F2 Fibroblast growth factor 23: State of the field and future directions ENSG00000118972 ENSG00000152266 ENSG00000140564 ENSG00000115339 ENSG00000109062 ENSG00000077782 PMC9477627__F8 Identification of Molecular Targets and Underlying Mechanisms of Xiaoji Recipe against Pancreatic Cancer Based on Network Pharmacology ENSG00000157933 ENSG00000136997 ENSG00000112186 ENSG00000026103 PMC8340210__F1 Development of PARP inhibitor combinations for castration resistant prostate cancer unselected for homologous recombination repair mutations ENSG00000167258 ENSG00000143799 ENSG00000136492 ENSG00000083093 ENSG00000115392 ENSG00000139618 ENSG00000183765 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000108384 ENSG00000149554 ENSG00000138385 PMC10530558__F6 Illustration of Altered Glucose Dependency in Drug-Resistant Cancer Cells PMC10530558__F2 Illustration of Altered Glucose Dependency in Drug-Resistant Cancer Cells ENSG00000136997 ENSG00000159399 PMC10530558__F1 Illustration of Altered Glucose Dependency in Drug-Resistant Cancer Cells ENSG00000136997 PMC6215910__F7 Model illustrating the potential pathway from pseudohypoxia-induced cilia loss to increased cell proliferation and dysregulation of tumorigenesis relevant cilia-mediated signaling pathways in PCCs ENSG00000094631 ENSG00000134086 PMC2564980__F5 Genes with differential expression in the carcinoma and papillary adenocarcinoma tumors were assembled into distinct metabolic pathways ENSG00000070831 ENSG00000134982 ENSG00000291971 ENSG00000134363 ENSG00000168036 ENSG00000118971 ENSG00000196628 ENSG00000137801 ENSG00000175054 ENSG00000170365 ENSG00000117020 ENSG00000163914 ENSG00000188763 ENSG00000177283 ENSG00000146648 PMC2564980__F7 Higher expression of genes involved in O-glycan synthesis in the carcinoma compared to the papillary adenocarcinoma tumors ENSG00000164574 ENSG00000109586 PMC8556325__F1 KRAS pathway and targeted preclinical and clinical agents ENSG00000198793 ENSG00000146648 PMC6021495__F10 Working model proposed for the synergistic action of GH and insulin on IGF-I and -II expression in the carp liver ENSG00000171105 ENSG00000112964 ENSG00000198793 PMC5795449__F4 IDO1-mediated Tryptophan Depletion ENSG00000159128 ENSG00000111537 ENSG00000027697 PMC9576517__F2 Mouse models of nonalcoholic fatty liver disease (NAFLD): pathomechanisms and pharmacotherapies ENSG00000170608 ENSG00000183735 ENSG00000153208 ENSG00000108691 ENSG00000163235 ENSG00000150907 ENSG00000169710 ENSG00000179094 PMC9313121__F4 Differential Neuropathology, Genetics, and Transcriptomics in Two Kindred Cases with Alzheimer’s Disease and Lewy Body Dementia ENSG00000132639 PMC8944741__F7 Phyto-Carbazole Alkaloids from the Rutaceae Family as Potential Protective Agents against Neurodegenerative Diseases ENSG00000114200 ENSG00000125538 ENSG00000087085 ENSG00000167419 PMC9377080__F2 Diverse functions of FAT1 in cancer progression: good, bad, or ugly? ENSG00000083857 ENSG00000281324 ENSG00000162337 ENSG00000113070 ENSG00000138798 ENSG00000169047 ENSG00000198793 ENSG00000158458 ENSG00000146648 PMC9052917__F7 Complement dysregulation is associated with severe COVID-19 illness ENSG00000000971 ENSG00000166278 ENSG00000132693 ENSG00000062485 PMC8108610__F1 Entry, egress and vertical transmission of SARS-CoV-2 ENSG00000130234 ENSG00000184012 PMC4809647__F3 Highly heterogeneous, activated and short-lived regulatory T cells during chronic filarial infection ENSG00000213658 ENSG00000163599 ENSG00000277943 PMC6761256__F10 Putative mechanism of necroptosis and relative inflammatory responses during the development of CCI ENSG00000162711 ENSG00000118503 ENSG00000125538 ENSG00000189403 ENSG00000168404 PMC12112630__F17 Overexpression of miR-454-3p leads to the inhibition of STAT3 and ATG12, which are involved in molecular pathways promoting Chondrosarcoma cell proliferation and evasion of apoptotic and autophagic mechanisms ENSG00000152348 ENSG00000145782 ENSG00000168610 ENSG00000057663 PMC9681860__F1 Copper homeostasis and cuproptosis in health and disease ENSG00000136868 ENSG00000173992 ENSG00000138495 ENSG00000123191 ENSG00000166260 ENSG00000177556 ENSG00000133028 PMC9681860__F2 Copper homeostasis and cuproptosis in health and disease ENSG00000121897 ENSG00000182511 ENSG00000137714 PMC2673236__F1 Schematic illustration of one-carbon metabolism pathway ENSG00000124275 ENSG00000116984 PMC6681663__F1 Everolimus for the treatment of advanced pancreatic ductal adenocarcinoma (PDAC) ENSG00000102034 ENSG00000198793 ENSG00000164327 PMC6394863__F6 Fluid forces shape the embryonic heart: insights from zebrafish ENSG00000173706 ENSG00000018408 ENSG00000276799 PMC6934083__F1 Autophagy regulates the expression of HDAC proteins which in turn leads to altered transcription and enhanced tumor cell immunogenicity ENSG00000144895 ENSG00000198793 ENSG00000057663 PMC10136927__F3 Targeting Wnt signaling pathway by the latest technologies ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000112655 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000155760 PMC11667779__F3 Adenosine signaling in TAMs ENSG00000118520 PMC3843886__F2 Schematic of common signalling pathways underlying activity-dependent and leptin-dependent synaptic plasticity ENSG00000168610 PMC6850109__F1 Pathogenesis of antibody‐mediated rejection and potential therapeutic targets ENSG00000119912 PMC7921060__F6 BMP/Hippo signaling modulating VEGFR pathway and angiogenic phenotype of endothelial cells ENSG00000128917 ENSG00000109321 ENSG00000019549 PMC5059634__F3 Parental vitamin deficiency affects the embryonic gene expression of immune-, lipid transport- and apolipoprotein genes ENSG00000291507 ENSG00000062485 PMC3967813__F2 IFNAlpha-2b signaling via JAK-STAT pathway, adapted from ENSG00000105397 ENSG00000099942 PMC3151145__F1 Intracellular lipid flux and membrane microdomains as organizing principles in inflammatory cell signaling ENSG00000135218 ENSG00000130164 ENSG00000170458 ENSG00000119655 ENSG00000113161 ENSG00000141458 ENSG00000136869 ENSG00000160179 ENSG00000075239 PMC8508945__F2 Translation Initiation Machinery as a Tumor Selective Target for Radiosensitization PMC6657652__F6 Antibactericidal mechanisms of C5a-TLR2 cross-talk induced by P ENSG00000172936 ENSG00000150455 PMC3854412__F7 SIRT1 negatively regulates amyloid-beta-induced inflammation via the NFKB pathway ENSG00000197713 ENSG00000096717 PMC5037286__F2 The NLRP3 inflammasome by the ubiquitin system ENSG00000162711 ENSG00000185515 ENSG00000136869 ENSG00000127191 PMC5378051__F3 Homologous mammalian and fungal host-defense pathways that signal through prion conversion ENSG00000162711 ENSG00000174145 PMC6657652__F2 Contrast inflammatory signals in human gingival fibroblasts triggered by the different acylation structures of P ENSG00000170458 ENSG00000136869 PMC6314538__F3 Cell cycle timing and regulation of replicative histone genes ENSG00000083223 ENSG00000136997 ENSG00000149308 PMC5661375__F2 Function of TGFB1 in normal lung and lung cancer cell responses to radiotherapy PMC5661375__F1 TGFB1 signaling pathway PMC4424078__F1 Viral Activation of Cellular Metabolism ENSG00000169710 ENSG00000159399 PMC6524506__F1 Hydrogen peroxide mediates pro-inflammatory cell-to-cell signaling: a new therapeutic target for inflammation? ENSG00000124102 ENSG00000125538 ENSG00000136869 PMC5721733__F8 Trimethylamine‐N‐Oxide Induces Vascular Inflammation by Activating the NLRP3 Inflammasome Through the SIRT3‐SOD2‐mtROS Signaling Pathway ENSG00000162711 ENSG00000142082 PMC6721535__F1 The catecholamine biosynthetic pathway in an adrenomedullary chromaffin cell or a pheochromocytoma cell ENSG00000205221 ENSG00000213658 ENSG00000123454 ENSG00000141744 PMC6387316__F3 Pathways controlling the response of physioxia MSC chondrogenesis ENSG00000139219 ENSG00000125398 ENSG00000157766 ENSG00000150907 ENSG00000158859 PMC7109575__F1 Role of the Wnt/Beta-catenin signaling pathway in chemoresistance of colorectal cancer ENSG00000137673 ENSG00000134982 ENSG00000168036 ENSG00000026103 PMC8345981__F1 TGF-Beta as a Master Regulator of Diabetic Nephropathy ENSG00000134871 PMC11688252__F2 Key signaling events underlying D-lactate-induced metabolic reprogramming in bFLS PMC6930194__F1 Schematic illustrating interaction of key elements in the tumor stroma in CCA progression ENSG00000178860 ENSG00000108691 ENSG00000170962 ENSG00000163739 ENSG00000112715 ENSG00000150630 PMC10688450__F4 Link between U2AF1 and NFKB signalling in MDS and AML ENSG00000115524 ENSG00000172936 ENSG00000135341 ENSG00000064012 PMC8592571__F8 Proposed cold-induced vasoconstriction signalling pathway in young and aged mice ENSG00000104321 PMC6160385__F5 Βeta-TRCP in regulating the Wnt signaling ENSG00000071564 ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000113558 ENSG00000136997 ENSG00000183579 ENSG00000026508 ENSG00000168036 PMC8533541__F2 Bioactive Scaffolds Integrated with Liposomal or Extracellular Vesicles for Bone Regeneration ENSG00000123374 ENSG00000204217 PMC5713305__F2 Nuclear factor erythroid 2-related factor 2 (Nrf2) regulatory pathway ENSG00000066926 ENSG00000178573 ENSG00000023909 ENSG00000079999 PMC3384412__F2 UPR signaling in diseases ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC1327682__F3 Schematic overview of the Saccharomyces cerevisiae central carbon metabolism ENSG00000074800 ENSG00000122966 ENSG00000172005 PMC4853753__F5 Cerebellum Development and Tumorigenesis: a p53-centric Perspective ENSG00000164690 ENSG00000128602 ENSG00000069667 ENSG00000172238 PMC6465609__F8 Schematic model of DHAV-1 inhibiting type I interferon signaling by hijacking the SOCS3 protein ENSG00000111537 ENSG00000115415 ENSG00000157601 ENSG00000135114 ENSG00000168610 ENSG00000164342 PMC9205118__F8 Identification of the key flavonoid and lipid synthesis proteins in the pulp of two sea buckthorn cultivars at different developmental stages ENSG00000101751 ENSG00000173599 ENSG00000285482 ENSG00000198670 ENSG00000166169 PMC11878485__F1 The role of signaling pathways in the mechanisms of glaucoma in retinal ganglion cells apoptosis, optical nerve protection and regeneration, and the LC damage and remodeling ENSG00000163914 PMC10137309__F3 Extravasation steps in lung cancer brain metastasis ENSG00000108691 ENSG00000163914 ENSG00000198074 ENSG00000168615 PMC10137309__F2 Extravasation steps in melanoma brain metastasis ENSG00000186810 ENSG00000087245 ENSG00000196154 ENSG00000100985 ENSG00000052126 ENSG00000122194 PMC11878485__F2 Review of glaucoma related signaling pathways and their mechanisms ENSG00000002330 ENSG00000102871 ENSG00000127191 ENSG00000122194 PMC4192461__F11 Proposed schematic for the maturation of mNT and its role in exporting mitochondrial Fe-S and reactivating the cytosolic apo-IRP1 into Fe-S aconitase after H2O2-induced oxidative and nitrosative stress ENSG00000005194 ENSG00000103274 ENSG00000070444 ENSG00000136003 PMC11878485__F4 The Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC7641192__F3 Calcium signalling pathway (map04020) obtained from KEGG database with official permission and guidance from Kanehisha Laboratories (permission ref 200,290) ENSG00000182533 ENSG00000156026 ENSG00000186716 PMC10137309__F1 Extravasation steps in breast cancer brain metastasis ENSG00000117228 ENSG00000113070 ENSG00000272398 ENSG00000173083 ENSG00000026508 ENSG00000187764 ENSG00000100985 ENSG00000121966 PMC4388007__F4 Significantly affected canonical pathway “interferon signaling”, as determined by IPA® analysis ENSG00000068079 ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000089127 ENSG00000033800 ENSG00000157601 ENSG00000171791 ENSG00000125347 ENSG00000230034 PMC6365940__F9 Pathway involved in gemcitabine-resistant pancreatic cancer cells with digoxin treatment ENSG00000114770 ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC8264328__F1 One carbon metabolism in human lung cancer ENSG00000065911 ENSG00000100714 PMC4659372__F1 PD-1 signaling in effector T cells ENSG00000145604 ENSG00000094631 ENSG00000061273 ENSG00000048052 ENSG00000049768 ENSG00000096717 PMC3385961__F1 Evolution of Wnt pathways ENSG00000291971 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC3031560__F5 Identification of Novel Molecular Targets for Endometrial Cancer Using a Drill-Down LC-MS/MS Approach with iTRAQ ENSG00000165119 ENSG00000145192 ENSG00000106483 ENSG00000158874 ENSG00000171560 PMC8551152__F6 Schematic diagram ENSG00000163958 ENSG00000133048 ENSG00000105329 ENSG00000026508 ENSG00000205250 PMC3973207__F8 Schematic diagram showing differences in the thyroid cancer cell lines sensitive or resistant to apoptosis ENSG00000002330 PMC4918620__F4 MAPK signaling pathway (orange nodes are associated with upregulated or only whole dataset genes and green nodes have no significance) ENSG00000170458 ENSG00000127191 ENSG00000081189 ENSG00000026103 PMC3518257__F7 14-3-3 signaling canonical pathway from IPA ENSG00000110711 ENSG00000002330 ENSG00000110395 ENSG00000131095 PMC4867619__F3 IPA analysis: (Panel a) Top Network Cell Death and Survival, Inflammatory Response, Cancer ENSG00000262406 ENSG00000102245 ENSG00000254445 ENSG00000117983 ENSG00000164342 PMC4405237__F1 Diversification of importinA isoforms in cellular trafficking and disease states ENSG00000099901 ENSG00000132341 PMC7698114__F2 Difference of two variants of CDK20 ENSG00000143553 ENSG00000123374 ENSG00000134480 PMC4483546__F1 Metformin on hepatocyte energy status and the mammalian target of rapamycin pathway, in turn affecting metabolism and inflammation ENSG00000138798 ENSG00000198793 ENSG00000155792 PMC9573519__F2 Research Progress on the Positive and Negative Regulatory Effects of Rhein on the Kidney: A Review of Its Molecular Targets ENSG00000175567 ENSG00000168040 ENSG00000026103 PMC9573519__F1 Research Progress on the Positive and Negative Regulatory Effects of Rhein on the Kidney: A Review of Its Molecular Targets ENSG00000239732 ENSG00000125538 ENSG00000198793 ENSG00000163064 ENSG00000100985 PMC8069505__F3 Important molecular mechanisms by which AEG-1 induces chemoresistance ENSG00000188641 ENSG00000198793 ENSG00000057663 PMC9194098__F2 Traditional Chinese Medicine in Bone Regeneration and Osteoporosis ENSG00000168036 ENSG00000075213 PMC10812436__F3 Main anti-inflammatory properties of HDLs ENSG00000108691 ENSG00000162692 PMC8348456__F1 Inflammatory Response in COVID-19 Patients Resulting from the Interaction of the Inflammasome and SARS-CoV-2 ENSG00000278718 ENSG00000162711 ENSG00000130234 ENSG00000125538 ENSG00000184012 PMC9360520__F1 Deciphering the myth of icariin and synthetic derivatives in improving erectile function from a molecular biology perspective: a narrative review PMC11600669__F1 Signaling pathway according to KEGG (A) NAFLD and (B) PPAR PMC7803009__F1 Congenital Malformations in Pregnancies with Pre-existing Diabetes ENSG00000088305 ENSG00000135903 PMC10494486__F7 Signaling model for late-phase IP-10 induction by MRP8/14 in endotoxic mice ENSG00000186810 ENSG00000105397 ENSG00000115415 ENSG00000136869 ENSG00000276561 PMC6161739__F5 Current model of NLRP3 subcellular localization during its activation process.Notes: Primed NLRP3 is both cytosolic and associated with endoplasmic reticulum (eR) ENSG00000278718 ENSG00000162711 ENSG00000088888 ENSG00000116688 ENSG00000007047 PMC2603035__F3 Hereditary haemorrhagic telangiectasia: current views on genetics and mechanisms of disease ENSG00000105329 ENSG00000171759 PMC8875910__F1 Multifaceted Roles of Mast Cells in Immune Homeostasis, Infections and Cancers ENSG00000172936 ENSG00000150455 ENSG00000010671 PMC7092503__F7 Differentially expressed interactors of APE1 in colorectal cancer ENSG00000128951 ENSG00000140740 ENSG00000117118 ENSG00000152620 ENSG00000169710 ENSG00000129351 ENSG00000111737 ENSG00000127884 ENSG00000004478 ENSG00000105486 ENSG00000132781 ENSG00000104980 ENSG00000097021 ENSG00000149273 ENSG00000148175 ENSG00000002549 ENSG00000185825 ENSG00000130204 ENSG00000072756 ENSG00000164587 ENSG00000173786 ENSG00000105953 ENSG00000010256 ENSG00000131828 ENSG00000101365 ENSG00000215021 ENSG00000137992 ENSG00000106554 ENSG00000165688 ENSG00000096717 ENSG00000196290 ENSG00000105379 PMC7754013__F1 MicroRNAs in osteogenic transdifferentiation of VSMCs ENSG00000121989 ENSG00000136011 ENSG00000178585 ENSG00000143878 ENSG00000120149 ENSG00000188064 ENSG00000196591 ENSG00000288488 ENSG00000203727 ENSG00000108840 PMC6161739__F2 NLRP3 inflammasome assembly ENSG00000278718 ENSG00000162711 PMC7507121__F2 TGFB signaling pathway ENSG00000143799 ENSG00000136807 ENSG00000140564 ENSG00000132964 PMC7468432__F1 Development and differentiation of Breg cells ENSG00000177455 ENSG00000272398 ENSG00000026508 ENSG00000121966 PMC6161739__F1 Canonical and non-canonical inflammasomes.Notes: Canonical inflammasomes assemble downstream of cytosolic PRRs including NLRP1, NLRP3, NLRC4, AIM2, and pyrin and control the activation of caspase-1 ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000091592 ENSG00000091106 PMC2803240__F8 Model of VA metabolism in neonatal rat lung ENSG00000121207 ENSG00000003137 PMC6161739__F3 NLRP3 priming following TLR activation ENSG00000162711 ENSG00000172936 ENSG00000136869 ENSG00000168040 ENSG00000184216 ENSG00000164342 PMC7507121__F3 Tumor suppressor and promoting functions of TGFB signaling ENSG00000167772 ENSG00000121966 PMC7468432__F2 Activation of Breg cells ENSG00000186716 ENSG00000137265 ENSG00000172936 ENSG00000103522 PMC5009326__F3 Integration of transcriptomic and genomic data suggests candidate mechanisms for APOE4-mediated pathogenic action in Alzheimer’s disease ENSG00000135547 ENSG00000142192 ENSG00000005339 ENSG00000108773 ENSG00000196782 ENSG00000021645 ENSG00000160691 ENSG00000103769 ENSG00000196498 ENSG00000133961 ENSG00000114315 ENSG00000114166 ENSG00000100603 PMC8003624__F3 Fungal induction of necroptosis ENSG00000187796 ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC4266326__F2A Comprehensive analysis of the transcriptional response of human decidual cells to lipopolysaccharide stimulation ENSG00000171855 ENSG00000166090 ENSG00000162892 PMC4881529__F4 GPCR-mediated transactivation of EGFR ENSG00000291971 ENSG00000138798 ENSG00000137845 ENSG00000146648 ENSG00000148848 PMC4286677__F8 Scheme of interactions hypothesized to connect the receptor protein Draper to the execution of the engulfment process ENSG00000070831 ENSG00000291971 ENSG00000163914 PMC4881529__F3 Diversity in GPCR-mediated regulation of Wnt/Beta-catenin ENSG00000134982 ENSG00000168036 PMC7236057__F8 Possible mechanisms of La2O3 NPs contributing to the apoptosis of testes tissues ENSG00000125538 ENSG00000214285 ENSG00000079999 PMC4181723__F7 Proposed TLR signaling mechanism by CS14K: a hypothetical model of TLR4 signaling, pathway activated by fusion protein, in a MyD88-independent fashion ENSG00000115415 ENSG00000172936 ENSG00000175104 PMC8361327__F2 Functional and Clinical Characteristics of Cell Adhesion Molecule CADM1 in Cancer ENSG00000122691 ENSG00000182985 PMC8361327__F1 Functional and Clinical Characteristics of Cell Adhesion Molecule CADM1 in Cancer ENSG00000139926 ENSG00000182985 PMC5534384__F2 The diversity and plasticity of adult hepatic progenitor cells and their niche ENSG00000019991 ENSG00000168283 ENSG00000226275 ENSG00000163235 ENSG00000138798 ENSG00000168036 PMC7773908__F7 Positive crosstalk between epidermal growth factor receptor (EGFR) and the platelet-activating factor (PAF) pathway in cervical cancer cells ENSG00000087253 ENSG00000173599 ENSG00000146648 PMC7157599__F3 Molecular mechanisms used by members of the HECT E3 ubiquitin ligases to regulate Wnt, TGFB and Notch signaling pathways ENSG00000069869 ENSG00000078747 ENSG00000134982 ENSG00000104517 ENSG00000198742 ENSG00000168036 ENSG00000086758 ENSG00000123124 PMC1828071__F2 Insulin-mediated activation of PI3K signaling pathways ENSG00000002330 ENSG00000005882 ENSG00000198793 ENSG00000164327 ENSG00000105723 PMC8472694__F2 Perspectives on Mitochondria–ER and Mitochondria–Lipid Droplet Contact in Hepatocytes and Hepatic Lipid Metabolism ENSG00000119737 ENSG00000116688 ENSG00000156026 ENSG00000173599 ENSG00000171109 ENSG00000133027 PMC1828071__F3 Diagrammatic representation of insulin on growth factor signaling through the Ras-Raf, MEK-ERK signaling pathway with downstream effects on gene transcription through ERK translocation ENSG00000106070 PMC3501223__F1 Role of Esrrb in ESC self-renewal and reprogramming ENSG00000071564 ENSG00000101115 ENSG00000128342 ENSG00000119715 PMC6450419__F4 Watch what you (self-) eat: Autophagic mechanisms that modulate metabolism ENSG00000123240 ENSG00000083635 ENSG00000284099 ENSG00000158828 PMC3866688__F5 Targets of immunosuppressive drugs used in solid organ transplantation, according to the 3-signal model of T-cell activation ENSG00000198793 ENSG00000105639 PMC7890028__F1 Wnt signaling pathways and their modulation by pharmacological molecules ENSG00000134982 ENSG00000168036 PMC5428427__F8 Proposed model for the suppression of inflammatory cytokine production by globular adiponectin in LPS-stimulated macrophages ENSG00000159346 ENSG00000285070 ENSG00000175104 ENSG00000079999 PMC6966193__F2 S1PC induces the degradation of MyD88 and Pax5 by activating autophagy ENSG00000108691 ENSG00000196092 ENSG00000172936 ENSG00000100219 PMC8484567__F6 Dramatic transcriptomic differences in Macaca mulatta and Macaca fascicularis with Plasmodium knowlesi infections ENSG00000104365 ENSG00000213928 ENSG00000187608 ENSG00000140968 ENSG00000163739 ENSG00000163568 ENSG00000178752 ENSG00000157601 ENSG00000127191 ENSG00000125347 ENSG00000276561 ENSG00000172183 ENSG00000184979 ENSG00000150782 ENSG00000169245 ENSG00000111537 ENSG00000088888 ENSG00000163840 ENSG00000105397 ENSG00000138755 ENSG00000135114 ENSG00000136869 ENSG00000131323 PMC7889583__F1 Multiple MDSC-mediated immunosuppressive mechanisms ENSG00000115415 ENSG00000134982 ENSG00000136997 ENSG00000172936 ENSG00000118520 ENSG00000100985 ENSG00000168610 PMC3986565__F1 Molecular pathways leading to cross-presentation in DCs ENSG00000232326 PMC3902304__F1 TWEAK/Fn14 signaling cascade ENSG00000104856 ENSG00000140564 ENSG00000082512 ENSG00000173039 ENSG00000175104 ENSG00000127191 PMC7889583__F3 Resistance mechanisms to MDSC immunosuppression ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC12250417__F4 Signal transduction mediated by BCR, FcRL1, CD19, and BCMA receptors on B-cells ENSG00000177455 ENSG00000070831 ENSG00000132646 ENSG00000186716 ENSG00000115904 ENSG00000197943 ENSG00000010671 ENSG00000163534 PMC9598604__F1 Impact of an Adapted Physical Activity Program on Bone Turnover, Physical Performance and Fear of Falling in Osteoporotic Women with Vertebral Fractures: A Quasi-Experimental Pilot Study ENSG00000178860 ENSG00000152266 ENSG00000125538 PMC9440249__F10 E-375i elicited anti-PCa effects ENSG00000143799 ENSG00000088179 ENSG00000137673 ENSG00000171791 ENSG00000100985 ENSG00000168610 PMC12119567__F4 Immune-metabolic crosstalk in HNSCC: mechanisms and therapeutic opportunities ENSG00000057252 ENSG00000198793 ENSG00000132326 PMC8389199__F8 Luteolin Alleviates AflatoxinB1-Induced Apoptosis and Oxidative Stress in the Liver of Mice through Activation of Nrf2 Signaling Pathway ENSG00000181019 ENSG00000079999 PMC10379831__F1 Deciphering the Signaling Mechanisms of Osteosarcoma Tumorigenesis ENSG00000167601 ENSG00000169554 ENSG00000002330 ENSG00000125398 ENSG00000198793 ENSG00000136997 ENSG00000171791 ENSG00000128602 PMC7438746__F4 Transcriptional regulation by mTORC1 ENSG00000101751 ENSG00000178573 ENSG00000112561 ENSG00000168610 PMC3176402__F4 Zn and Zn transporters are indispensable for FcERI-mediated mast cell activation ENSG00000033327 ENSG00000010810 PMC7438746__F3 Indirect transcriptional control by AMPK through metabolites of intermediary metabolism ENSG00000147162 ENSG00000187605 ENSG00000138336 ENSG00000198408 ENSG00000077463 PMC3547956__F6 Transcriptional and Gene Regulatory Network of Lactococcus lactis MG1363 during Growth in Milk ENSG00000147162 ENSG00000156110 ENSG00000173039 ENSG00000146676 PMC5334292__F1 The possible role of the polyol pathway in diabetes atherosclerosis ENSG00000124479 ENSG00000105835 PMC5105243__F2 Possible mechanisms for neuroprotective function of exercise and differences between sexes ENSG00000168209 ENSG00000197081 ENSG00000121742 PMC3082570__F1 Simultaneous siRNA Targeting of Src and Downstream Signaling Molecules Inhibit Tumor Formation and Metastasis of a Human Model Breast Cancer Cell Line ENSG00000002330 ENSG00000291971 ENSG00000198793 ENSG00000168610 PMC2322867__F2 Rapid Signaling Mechanisms of Estrogens in the Developing Cerebellum ENSG00000291971 ENSG00000113070 ENSG00000146648 PMC8551128__F1 Complement activation in IgA nephropathy ENSG00000039537 ENSG00000009724 ENSG00000291559 ENSG00000013441 ENSG00000288512 ENSG00000166278 ENSG00000182326 PMC4301092__F2 Examples of PTM-mediated biological processes ENSG00000126457 ENSG00000159335 PMC3587843__F4 Lipids in The Control of Autophagy ENSG00000124102 ENSG00000173599 ENSG00000115020 PMC11097647__F6 B cell receptor signaling pathway-enriched Module_01 ENSG00000174123 ENSG00000117971 ENSG00000065357 ENSG00000172578 ENSG00000007312 ENSG00000196839 ENSG00000176928 ENSG00000188372 ENSG00000177455 ENSG00000176399 ENSG00000161791 ENSG00000113749 ENSG00000169851 ENSG00000171798 PMC5689203__F1 Schematic representation of secretory protein folding and quality control, the unfolded protein response pathway, and the heat shock response ENSG00000094631 ENSG00000284774 PMC9171972__F2 YAP1 in liver cancer stem cells: proven and potential mechanisms ENSG00000197081 ENSG00000162337 ENSG00000168036 ENSG00000131023 ENSG00000140443 PMC3475803__F7 A model depicting ATM- and NEMO-mediated NFKB activation upon accumulation of prelamin A isoforms ENSG00000149311 ENSG00000163739 ENSG00000173039 PMC3742223__F1 Ageing-dependent decline in thyroid activity, leading to compensatory increases in cellular D1 activity and thyroid hormone metabolites that may, through non-genomic pathways, be involved in amelioration of ageing related metabolic disturbances ENSG00000171105 ENSG00000154059 ENSG00000096717 PMC8204022__F4 MicroRNA-Based Network Provides Potential Predictive Signatures and Reveals the Crucial Role of PI3K/AKT Signaling for Hepatic Lineage Maturation ENSG00000253293 ENSG00000151726 ENSG00000109906 ENSG00000162772 ENSG00000146278 ENSG00000136826 ENSG00000196628 ENSG00000069667 ENSG00000151702 ENSG00000245848 ENSG00000168283 ENSG00000159216 ENSG00000172216 ENSG00000078900 ENSG00000122691 ENSG00000179348 ENSG00000282899 ENSG00000172530 ENSG00000182578 ENSG00000165891 ENSG00000168874 ENSG00000187772 ENSG00000183734 ENSG00000124216 ENSG00000106780 ENSG00000164107 ENSG00000107485 ENSG00000067955 ENSG00000096717 ENSG00000113448 ENSG00000180694 ENSG00000157554 ENSG00000104856 ENSG00000100234 ENSG00000120519 ENSG00000176422 ENSG00000119401 ENSG00000117139 ENSG00000168036 ENSG00000049768 ENSG00000110801 ENSG00000180210 ENSG00000131914 ENSG00000188811 ENSG00000185591 ENSG00000116044 ENSG00000109320 ENSG00000138411 ENSG00000066135 ENSG00000173039 ENSG00000168610 ENSG00000185652 ENSG00000260027 ENSG00000128272 ENSG00000115415 ENSG00000100784 ENSG00000074266 ENSG00000126778 ENSG00000114166 PMC10373120__F5 Regulatory pathway involving lncRNA H19, miR-124-3p and ITGB3 in modulating ectopic endometrial cell proliferation and invasion in endometriosis ENSG00000259207 PMC5077967__F8 microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NFKB ENSG00000104856 ENSG00000081041 ENSG00000140379 ENSG00000102871 ENSG00000108342 ENSG00000173039 ENSG00000184371 ENSG00000162924 PMC6915012__F7 Schematic representation of the PAME-induced G2/M arrest in hBM-MSCs PMC10880550__F1 Effect of acetylcholine released from cholinergic neuron on heart, visceral smooth muscles and the brain ENSG00000133107 ENSG00000072315 PMC9511018__F2 Non-cytotoxic functions of CD8 T cells: “repentance of a serial killer” ENSG00000169245 ENSG00000111537 ENSG00000138755 ENSG00000026103 PMC6061679__F1 Parkinson’s disease genes reveal an association of multiple variants that converge on deficiencies in cellular clearance ENSG00000129003 ENSG00000155961 ENSG00000078081 ENSG00000103510 ENSG00000119899 ENSG00000078070 ENSG00000158828 ENSG00000069329 ENSG00000141458 ENSG00000127419 ENSG00000167186 PMC7118073__F7 Exosome-transmitted lncRNA UFC1 promotes non-small-cell lung cancer progression by EZH2-mediated epigenetic silencing of PTEN expression ENSG00000143222 PMC10880550__F5 Complex interactions among GIRK, TRPC1/4/5 and KCNQ channels with GPCRs via G proteins A or BG subunits and PIP2 in neurons ENSG00000133107 ENSG00000144935 ENSG00000170893 ENSG00000072315 PMC2173816__F3 Down-regulation of the inflammatory response ENSG00000132906 ENSG00000164305 PMC7946926__F8 Transport mechanism ENSG00000135605 PMC6596994__F7 A Conserved PLPLRT/SD Motif of STING Mediates the Recruitment and Activation of TBK1 ENSG00000183735 ENSG00000164430 PMC6905042__F2 Proposed mechanisms of Wnt/Beta-catenin dysregulation in ovarian cancer ENSG00000281324 ENSG00000138764 ENSG00000162337 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000285438 ENSG00000234616 ENSG00000119396 ENSG00000173273 PMC3243033__F1 Regulation of epidermal homeostasis by PCP signaling ENSG00000164932 ENSG00000169071 ENSG00000158055 ENSG00000070831 ENSG00000100592 ENSG00000173218 ENSG00000143126 ENSG00000075275 ENSG00000010361 ENSG00000112655 ENSG00000008300 ENSG00000076716 PMC8721007__F2 Targeting Metabolic Pathways of Myeloid Cells Improves Cancer Immunotherapy ENSG00000117054 ENSG00000135218 ENSG00000115419 ENSG00000159399 PMC6905042__F1 The Wnt/Beta-catenin signalling pathway ENSG00000134982 ENSG00000168036 PMC155355__F7 Model outlining the roles of GAI/RGA-like GA-signaling components in the plant life cycle ENSG00000205517 ENSG00000171560 PMC4562157__F5 Genes involved in metabolism (EMP pathway, TCA cycle, and inositol metabolism), rhizosphere adaptation, biocontrol, and plant growth promotion in SQR9 and their expression patterns in response to root exudates ENSG00000105664 ENSG00000093217 ENSG00000169299 PMC8721007__F3 Targeting Metabolic Pathways of Myeloid Cells Improves Cancer Immunotherapy ENSG00000074800 ENSG00000135218 ENSG00000159399 PMC7185105__F9 Hypothetical scheme of molecular and cellular events in the cochleae of aging Tg-B1 mice leading to accelerated hearing loss ENSG00000177169 ENSG00000198793 PMC10380881__F1 Genetic Modulation of the Erythrocyte Phenotype Associated with Retinopathy of Prematurity—A Multicenter Portuguese Cohort Study ENSG00000228716 ENSG00000004487 ENSG00000124275 ENSG00000116984 PMC3374856__F3 Mutations in glutamate signaling pathway and its associated proteins in melanoma ENSG00000158458 ENSG00000169752 ENSG00000178568 PMC8866648__F2 Vascular Stem/Progenitor Cells in Vessel Injury and Repair ENSG00000281324 ENSG00000162337 ENSG00000050165 ENSG00000168036 PMC12138082__F2 Antiviral mechanism of miR-124, miR-24, and miR-744 ENSG00000115415 ENSG00000136997 PMC8012850__F6 Schematic representations of the gene regulatory pathway controlled by Oc factors in the chordate retina ENSG00000089116 ENSG00000013293 ENSG00000145863 ENSG00000135903 ENSG00000117707 ENSG00000285493 ENSG00000179104 ENSG00000145920 ENSG00000009709 ENSG00000151834 ENSG00000079689 ENSG00000111837 ENSG00000157445 PMC2810615__F1 Simplified overview of the canonical Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC7145982__F1 Autophagy process and regulation of ATG proteins by PTMs ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000198382 ENSG00000083290 ENSG00000144848 ENSG00000158828 ENSG00000145782 ENSG00000182858 ENSG00000057663 PMC10974036__F12 Recent Advances in the Nutritional Value, Chemical Compositions, Pharmacological Activity, and Application Value of Orychophragmus violaceus: A Comprehensive Review ENSG00000128272 ENSG00000178573 ENSG00000130522 ENSG00000079999 PMC10937455__F1 The intrinsic immune system in the pathogenesis of GN ENSG00000162711 ENSG00000170458 ENSG00000172936 PMC12138082__F8 Vital role of the AMPK signaling pathway in cellular progress ENSG00000126775 ENSG00000198793 ENSG00000265972 PMC3917352__F1 Major metabolic pathways in tumour cells ENSG00000131473 ENSG00000115419 PMC3403522__F2 Intracellular HIF-1A regulation pathway in normoxia and hypoxia ENSG00000134086 ENSG00000198793 ENSG00000146648 PMC4453221__F1 Wnt/Beta-catenin signalling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000104332 PMC8830536__F2 Lipoprotein(a), a Lethal Player in Calcific Aortic Valve Disease ENSG00000168036 ENSG00000136869 ENSG00000198670 ENSG00000121807 PMC12138082__F4 Proviral mechanisms of miRNAs ENSG00000213928 ENSG00000107562 ENSG00000125347 ENSG00000168610 ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000160219 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC12138082__F3 Mechanism of miR-342-5p regulating sterol metabolism ENSG00000067064 ENSG00000115415 ENSG00000113161 ENSG00000160179 ENSG00000125347 PMC11046063__F1 NRF2 signalling pathway ENSG00000100387 ENSG00000079999 PMC2789670__F5 Summary of glutathione (l-Gamma-glutamyl-l-cysteinylglycine, GSH) homeostasis pathway identified in C ENSG00000173221 ENSG00000185022 ENSG00000023909 ENSG00000156273 ENSG00000079999 PMC9032805__F3 Tumor Microenvironment Drives Intrahepatic Cholangiocarcinoma Progression ENSG00000214513 ENSG00000189043 ENSG00000132698 ENSG00000169032 ENSG00000164953 PMC6287681__F3 Signaling pathways by which NPs induce apoptosis ENSG00000132906 ENSG00000291983 ENSG00000138794 ENSG00000120868 ENSG00000168040 ENSG00000064012 ENSG00000164305 PMC6287681__F2 Signaling pathways that induce necroptosis ENSG00000137275 ENSG00000168040 ENSG00000064012 ENSG00000285379 PMC10145673__F2 Molecular pathways involved in pituitary tumorigenesis ENSG00000002330 ENSG00000134982 ENSG00000168036 ENSG00000128602 ENSG00000146648 ENSG00000131023 ENSG00000140443 PMC10145673__F1 G-protein-coupled receptor (GPCR) signaling pathway ENSG00000110711 ENSG00000291971 ENSG00000198793 ENSG00000146648 ENSG00000106546 PMC12069192__F2 Regulation mechanisms of LMM proteins in rice ENSG00000144566 ENSG00000166278 ENSG00000080839 PMC6287681__F4 Autophagy signaling pathways induced by NPs ENSG00000124102 ENSG00000177169 ENSG00000152348 ENSG00000042832 ENSG00000126775 ENSG00000196455 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC3185509__F1 Activation of antiviral and proinflammatory responses during HSV infections ENSG00000239732 ENSG00000088888 ENSG00000119487 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC3185509__F3 Innate immune evasion mechanisms of HSV ENSG00000239732 ENSG00000088888 ENSG00000135828 ENSG00000164342 PMC3625183__F7 Zoledronic Acid Restores Doxorubicin Chemosensitivity and Immunogenic Cell Death in Multidrug-Resistant Human Cancer Cells ENSG00000171540 ENSG00000184207 PMC9179574__F3 Genetic Structure and Molecular Mechanisms Underlying the Formation of Tassel, Anther, and Pollen in the Male Inflorescence of Maize (Zea mays L.) ENSG00000066336 ENSG00000115904 PMC11357136__F2 Several modulator molecules linked to the signaling of GLP-1 receptor within the PI3K/AKT/mTOR pathway are demonstrated ENSG00000177169 ENSG00000164327 PMC8431684__F2 Therapeutic Potential of Targeting the SUMO Pathway in Cancer ENSG00000157554 ENSG00000079387 ENSG00000033800 ENSG00000116030 ENSG00000140464 PMC8579463__F8 miR-34a-5p functions as a tumor suppressor in head and neck squamous cell cancer progression by targeting Flotillin-2 ENSG00000135446 ENSG00000170558 ENSG00000105810 PMC4882535__F5 Identifications of novel mechanisms in breast cancer cells involving duct-like multicellular spheroid formation after exposure to the Random Positioning Machine ENSG00000132906 ENSG00000148346 ENSG00000112715 ENSG00000164305 ENSG00000092820 ENSG00000188153 ENSG00000148498 ENSG00000053747 ENSG00000082175 ENSG00000163558 ENSG00000102981 ENSG00000169429 ENSG00000101162 PMC4882535__F4 Identifications of novel mechanisms in breast cancer cells involving duct-like multicellular spheroid formation after exposure to the Random Positioning Machine ENSG00000132906 ENSG00000148346 ENSG00000112715 ENSG00000164305 ENSG00000092820 ENSG00000188153 ENSG00000148498 ENSG00000053747 ENSG00000082175 ENSG00000163558 ENSG00000102981 ENSG00000128052 ENSG00000169429 ENSG00000101162 PMC5413082__F1 Schematic of growth hormone and IGF-1 axis ENSG00000291972 ENSG00000112964 ENSG00000140443 PMC9417995__F7 Schematic description of TRAF4/SMURF2-mediated regulation of HER2 signaling and Trastuzumab resistance in HER2+breast cancer cells ENSG00000198793 ENSG00000076604 PMC4655423__F1 Development of innate lymphoid cells ENSG00000111537 ENSG00000137033 ENSG00000165030 ENSG00000125538 ENSG00000020633 ENSG00000107485 ENSG00000145777 ENSG00000198846 ENSG00000166090 ENSG00000106546 ENSG00000069667 PMC3117004__F2 Updated most likely pathway for acylCer formation (November 2010) ENSG00000118402 ENSG00000042832 ENSG00000062282 PMC2150790__F9 The signaling pathways activated by N ENSG00000070831 ENSG00000291971 ENSG00000163914 ENSG00000026508 PMC11983503__F3 Regulatory mechanisms of D-catenin associated with neural development and function ENSG00000134982 ENSG00000164327 ENSG00000292254 PMC6520728__F6 Schematic diagram for a proposed molecular mechanism of CFH regulation in lung cancers ENSG00000138378 ENSG00000000971 PMC11983503__F2 CTNND2 involved in the WNT/Beta-catenin pathway ENSG00000103037 ENSG00000134982 ENSG00000168036 ENSG00000077782 ENSG00000130669 PMC2967651__F1 A model for interplay between alloimmunity and autoreactivity in graft rejection ENSG00000111537 PMC7764362__F4 Main action mechanisms of chloroquine (CQ) and hydroxychloroquine (HCQ) related to antiviral and immunomodulators properties ENSG00000213928 ENSG00000239732 ENSG00000115415 ENSG00000276561 ENSG00000164342 PMC3343200__F5 IL-6 contributes to a positive feedback cycle of growth and invasion between CAFs (myofibroblasts) and its underlying tumor (afferent pathway) and between invading tumor and the recruitment of fibroblasts to myofibroblasts (efferent pathway) ENSG00000074181 ENSG00000138798 ENSG00000168610 PMC2697824__F3 Improving gemcitabine-mediated radiosensitization using molecularly targeted therapy: A review ENSG00000149311 ENSG00000175054 ENSG00000051180 ENSG00000146648 PMC7764362__F2 Negative regulation of interferons (IFNs) by autophagy ENSG00000213928 ENSG00000167207 ENSG00000276561 ENSG00000142166 ENSG00000183735 ENSG00000239732 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000160703 ENSG00000134070 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000164342 PMC3843069__F1 Tryptophan metabolic pathway ENSG00000183077 PMC11722366__F2 Key signaling pathways involved in kidney fibrosis ENSG00000136535 ENSG00000105397 ENSG00000168610 PMC3291810__F8 PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling ENSG00000149269 ENSG00000168610 PMC8833906__F1 Nuclear Receptor PXR in Drug-Induced Hypercholesterolemia ENSG00000116133 ENSG00000113161 ENSG00000186480 ENSG00000104549 ENSG00000169174 PMC3147301__F3 Towards an understanding of the adjuvant action of aluminium ENSG00000162711 ENSG00000137033 ENSG00000172936 PMC4412056__F1 LC-PUFA biosynthesis pathway {adapted from Refs ENSG00000134824 ENSG00000149485 ENSG00000197977 PMC5407765__F9 IL-33 receptor ST2 regulates the cognitive impairments associated with experimental cerebral malaria ENSG00000169245 ENSG00000137033 ENSG00000138755 PMC9613427__F1 Gain-of-function TLR7 and loss-of-function A20 gene variants identify a novel pathway for Mendelian lupus and lupus nephritis ENSG00000186716 ENSG00000172936 ENSG00000276561 PMC7879300__F1 Toll-Like Receptors Regulate the Development and Progression of Renal Diseases ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC313952__F6 Caenorhabditis elegans SOS-1 is necessary for multiple RAS-mediated developmental signals ENSG00000110395 ENSG00000138433 ENSG00000138798 ENSG00000115904 ENSG00000146648 PMC11900975__F2 Multiple mechanisms of T-cell exhaustion induced by neutrophils in the TME ENSG00000105835 ENSG00000162551 ENSG00000168610 PMC3594247__F1 Hippo on the move ENSG00000150457 ENSG00000131023 PMC8776955__F5 Calcineurin-dependent NFAT signaling as shared signaling pathway for IBD and SCZ ENSG00000002330 ENSG00000170027 ENSG00000175793 ENSG00000126883 ENSG00000101266 ENSG00000171791 ENSG00000164305 ENSG00000120910 ENSG00000221823 ENSG00000067606 ENSG00000166501 ENSG00000291761 ENSG00000131196 ENSG00000132341 PMC11931784__F8 Heatmap of DEGs involved in the JA synthesis pathway ENSG00000136997 PMC5110454__F1 DRAStic RHOAdblock of Pyrin inflammasome activation ENSG00000110921 ENSG00000123143 ENSG00000065243 PMC9482886__F2 AMPK regulation of the mTOR pathway and control of cell growth and autophagy ENSG00000177169 ENSG00000155792 ENSG00000167965 PMC3926678__F5 Repetitive hypoxic preconditioning suppresses adaptive immune responses in resident B cells prior to stroke ENSG00000005339 ENSG00000282905 ENSG00000168036 ENSG00000162924 ENSG00000125347 ENSG00000168811 ENSG00000177663 ENSG00000179344 ENSG00000115415 ENSG00000276051 ENSG00000137265 ENSG00000113520 ENSG00000274183 ENSG00000277263 ENSG00000126353 PMC5506009__F1 Functions of experimentally verified target genes of miR-17-92 were analyzed by GeneMANIA using genetic interactions, pathway, and physical interaction parameters ENSG00000108702 ENSG00000151490 ENSG00000115137 ENSG00000157404 ENSG00000178951 ENSG00000153094 ENSG00000127528 ENSG00000149308 ENSG00000176105 ENSG00000171791 ENSG00000139625 ENSG00000118971 ENSG00000112715 ENSG00000124762 ENSG00000137801 ENSG00000103479 ENSG00000117525 ENSG00000112242 ENSG00000128052 ENSG00000136997 ENSG00000124201 ENSG00000168310 ENSG00000291761 ENSG00000157514 ENSG00000139687 ENSG00000064012 ENSG00000282899 ENSG00000007944 ENSG00000142192 ENSG00000077585 ENSG00000137449 ENSG00000007908 ENSG00000168610 ENSG00000149311 ENSG00000066468 ENSG00000140299 ENSG00000103264 ENSG00000114166 ENSG00000204217 PMC6770178__F1 Substance P/neurokinin-1 receptor (SP/NK-1R) system regulates several cell signaling pathways involved in cancer progression ENSG00000134982 ENSG00000198793 ENSG00000163914 ENSG00000168036 PMC4401129__F1 Tie2 (Tie2 tyrosine kinase receptor) structure and Ang-1-Tie2 signallingsignaling ENSG00000198517 ENSG00000118520 ENSG00000122194 PMC4364006__F2 The molecular regulation of autophagy ENSG00000177169 ENSG00000110497 ENSG00000152348 ENSG00000198382 ENSG00000083290 ENSG00000126775 ENSG00000144848 ENSG00000145782 ENSG00000057663 ENSG00000062716 PMC7654218__F6 Effects of extracellular antagonists in the Wnt/Beta-cat signaling pathway during the proliferation and differentiation in human osteoblast ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000050165 ENSG00000104371 PMC3715701__F1 Myosin 1c in cellular signaling pathways ENSG00000070831 ENSG00000291971 ENSG00000149269 ENSG00000169047 PMC6520171__F3 Depiction of RBP4 immunomodulatory actions locally within and how this gives rise to insulin resistance ENSG00000138207 ENSG00000134982 ENSG00000125538 PMC5501910__F3 Rescuing the BMPRII signaling pathway in pulmonary arterial hypertension ENSG00000170365 PMC3660063__F3 Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response ENSG00000002330 ENSG00000198793 ENSG00000155792 ENSG00000168036 PMC8301375__F4 XBP1s in Transcriptional Regulation of Target Genes ENSG00000127445 ENSG00000136997 ENSG00000100219 ENSG00000096717 PMC3660063__F2 Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response ENSG00000138166 ENSG00000138798 ENSG00000146648 PMC3660063__F1 Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response ENSG00000177169 ENSG00000196455 ENSG00000198793 ENSG00000155792 ENSG00000133124 ENSG00000100442 ENSG00000121879 ENSG00000196712 PMC6928565__F1 Notch3 signalling and vascular remodelling in pulmonary arterial hypertension ENSG00000168214 ENSG00000184916 ENSG00000137845 PMC8301375__F1 XBP1s in Transcriptional Regulation of Target Genes ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC6766623__F12 Molecular mechanisms by which pretreatment with monophosphoryl lipid A (MPLA) suppresses LPS signaling in the medullary thick ascending limb ENSG00000172936 ENSG00000136869 ENSG00000184216 PMC12153709__F7 Graphical representation of the IL-4/IL-13 signaling pathway, including the genes described in Table 1 ENSG00000123496 ENSG00000105397 ENSG00000131724 ENSG00000006606 ENSG00000105639 ENSG00000168610 PMC3069698__F1 The Fanconi Anemia and Breast Cancer Susceptibility Pathways ENSG00000175054 ENSG00000144554 ENSG00000162607 ENSG00000139618 PMC8044463__F3 Metabolic genes regulated by Mondo family ENSG00000131473 ENSG00000151726 ENSG00000042832 ENSG00000138030 ENSG00000265972 ENSG00000062282 ENSG00000180210 ENSG00000065833 ENSG00000166391 ENSG00000198380 ENSG00000170522 ENSG00000138823 ENSG00000134824 ENSG00000149485 ENSG00000285482 ENSG00000080166 ENSG00000026103 PMC5916398__F1 Initial stages of the sensitization in contact dermatites ENSG00000125538 ENSG00000145777 ENSG00000136869 PMC9304701__F1 Trained Immunity and HIV Infection ENSG00000136869 ENSG00000140443 PMC3660063__F4 Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response ENSG00000177169 ENSG00000169047 ENSG00000198793 ENSG00000155792 ENSG00000167965 ENSG00000196712 PMC8082500__F8 KLF4, a Key Regulator of a Transitive Triplet, Acts on the TGFB Signaling Pathway and Contributes to High-Altitude Adaptation of Tibetan Pigs ENSG00000137834 ENSG00000189409 ENSG00000168874 ENSG00000128052 ENSG00000136826 PMC4343072__F6 Consequences of mutant BRAF V600E in LCH ENSG00000157764 ENSG00000172936 PMC8082500__F7 KLF4, a Key Regulator of a Transitive Triplet, Acts on the TGFB Signaling Pathway and Contributes to High-Altitude Adaptation of Tibetan Pigs ENSG00000137834 ENSG00000189409 ENSG00000168874 ENSG00000128052 ENSG00000136826 PMC8131834__F2 Targeting Parthanatos in Ischemic Stroke ENSG00000186063 ENSG00000173599 ENSG00000096717 PMC7916866__F1 Oxidative Stress, Plant Natural Antioxidants, and Obesity ENSG00000169047 ENSG00000140443 PMC8698543__F3 Understanding the Role of Estrogen Receptor Status in PRODH/POX-Dependent Apoptosis/Survival in Breast Cancer Cells ENSG00000102871 ENSG00000168040 ENSG00000026103 PMC6210393__F7 MAPK signaling pathway from KEGG database ENSG00000087095 ENSG00000170458 ENSG00000102871 ENSG00000138798 ENSG00000136997 ENSG00000198517 ENSG00000130159 ENSG00000081189 ENSG00000026103 PMC11978054__F5 Visualize interactions between the hub-genes in a co-expression blue module using GeneMAINA ENSG00000089472 ENSG00000214357 ENSG00000183111 ENSG00000172572 ENSG00000058091 ENSG00000291600 ENSG00000285222 ENSG00000110888 ENSG00000187772 ENSG00000171345 ENSG00000188153 ENSG00000110693 ENSG00000136231 ENSG00000071282 ENSG00000182247 PMC2785525__F1 The Anticoagulant APC Pathway ENSG00000134982 ENSG00000088926 ENSG00000122194 PMC11076649__F8 JCYSTLF exerted an anti-senescence effect through regulating the HIF-1A/autophagy pathway in diabetic kidneys ENSG00000057663 ENSG00000136874 PMC10139088__F6 Metabolic regulation on tumour metastasis ENSG00000124216 ENSG00000019549 PMC7010257__F5 miRNA expression in advanced Algerian breast cancer tissues ENSG00000065361 ENSG00000146648 ENSG00000187840 PMC7642854__F3 Endothelial dysfunction due to selective insulin resistance in vascular endothelium: insights from mechanistic modeling ENSG00000124102 ENSG00000169047 PMC10139088__F5 Metabolic plasticity regulation on tumour microenvironment ENSG00000079432 PMC2785525__F2 Cytoprotective APC pathway ENSG00000134982 ENSG00000162692 PMC7381294__F5 Differentially methylated genes enriched in the insulin signaling pathway ENSG00000005882 ENSG00000150907 ENSG00000198793 ENSG00000026103 PMC3049195__F1 Proposed diphthamide biosynthesis pathway ENSG00000154813 ENSG00000108963 PMC7381294__F7 Differentially methylated genes enriched in the AMPK signaling pathway ENSG00000168610 ENSG00000026103 PMC7381294__F6 Differentially methylated genes enriched in the adipocytokine signaling pathway ENSG00000168610 PMC6770718__F1 Schematic drawing presents the detailed signaling pathways of breast carcinogenesis ENSG00000019991 ENSG00000138798 ENSG00000168036 ENSG00000175104 PMC7172007__F1 Canonical Wnt/Beta-catenin signaling pathway and pharmacologic pathway mediators ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000106483 PMC4988654__F1 Major steps in the retinol signaling pathway of vertebrates ENSG00000121039 ENSG00000128918 ENSG00000162496 ENSG00000105991 PMC2246264__F9 Proposed mechanism for MnSOD-mediated mitochondria to nucleus signaling and crosstalk with the IIS pathway ENSG00000077150 ENSG00000143507 ENSG00000162924 PMC7211957__F7 Model illustrating the Thbs1/integrin/YAP signaling pathway in remodeling of vessel walls ENSG00000150457 ENSG00000131023 ENSG00000137801 PMC5342520__F2 Subpathway-LNCE: Identify dysfunctional subpathways competitively regulated by lncRNAs through integrating lncRNA-mRNA expression profile and pathway topologies ENSG00000196296 ENSG00000149091 ENSG00000178363 ENSG00000137825 ENSG00000067900 ENSG00000182621 ENSG00000118971 ENSG00000186298 ENSG00000161714 ENSG00000160691 ENSG00000182533 ENSG00000108179 ENSG00000130402 ENSG00000086544 PMC3160828__F1 More than just a T-box: the role of T-bet as a possible biomarker and therapeutic target in autoimmune diseases ENSG00000096996 ENSG00000138378 ENSG00000115415 ENSG00000020633 ENSG00000107485 PMC8898375__F10 Atractylenolide III ameliorates Non-Alcoholic Fatty Liver Disease by activating Hepatic Adiponectin Receptor 1-Mediated AMPK Pathway ENSG00000096717 ENSG00000142082 ENSG00000184743 PMC9286785__F5 BACE1: More than just a B‐secretase ENSG00000168610 PMC9286785__F4 BACE1: More than just a B‐secretase ENSG00000169047 ENSG00000168610 PMC4191651__F3 Schematic illustrating mechanisms of SR-A intracellular signaling ENSG00000239732 ENSG00000172936 ENSG00000164342 PMC11977285__F3 Extracellular vesicles (EVs) in mitigating MASLD ENSG00000019991 ENSG00000118520 ENSG00000176165 ENSG00000168610 PMC3356623__F6 Influence of Tc-axin and Tc-pangolin on canonical Wnt signaling and role of Wnt signaling in axis formation in the bilateria ENSG00000134982 ENSG00000168036 PMC7263617__F4 Expression of high mobility group B1 and toll-like receptor-nuclear factor KB signaling pathway in chronic subdural hematomas ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC9219682__F1 Enhanced 3T3-L1 Differentiation into Adipocytes by Pioglitazone Pharmacological Activation of Peroxisome Proliferator Activated Receptor-Gamma (PPARG) PMC5920280__F1 Metabotropic actions of kainate receptors (KARs) in the regulation of glutamate release in the hippocampus ENSG00000164879 PMC11968765__F2 Signal transduction mechanism of SWELL1 in different tissues and cells ENSG00000065978 ENSG00000150907 ENSG00000177606 ENSG00000037474 ENSG00000123374 ENSG00000171791 PMC8660088__F6 System Pharmacology Model for Decoding the Synergistic Mechanisms of Compound Kushen Injection in Treating Breast Cancer ENSG00000177455 ENSG00000104899 ENSG00000002330 ENSG00000119535 ENSG00000186716 ENSG00000169047 ENSG00000177606 ENSG00000136997 ENSG00000108342 ENSG00000136869 ENSG00000001626 ENSG00000121879 PMC4096159__F2 Emerging Role of Autophagy in Alcoholic Liver Disease ENSG00000198793 PMC11173950__F3 Oxidative stress: Nrf2 signaling pathway (adapted from Hammad et al ENSG00000100387 ENSG00000079999 PMC11782603__F8 Using SEC-MX to provide molecular insights ENSG00000100150 ENSG00000114388 ENSG00000155792 ENSG00000155876 ENSG00000065559 ENSG00000108443 ENSG00000281877 ENSG00000167965 ENSG00000285069 ENSG00000187840 ENSG00000183765 ENSG00000136807 ENSG00000175054 ENSG00000204673 PMC8544255__F4 Deregulation of the canonical Notch signalling pathway during CRC treatment ENSG00000112576 ENSG00000171791 ENSG00000114315 ENSG00000118777 PMC8544255__F3 Deregulation of the canonical Wnt/Beta-catenin signalling pathway during CRC treatment ENSG00000124422 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000171791 PMC8911851__F6 Investigating the Neurotoxic Impacts of Arsenic and the Neuroprotective Effects of Dictyophora Polysaccharide Using SWATH-MS-Based Proteomics ENSG00000088682 ENSG00000117480 ENSG00000140612 ENSG00000117500 ENSG00000196712 PMC5666614__F3 Lipids at membrane contact sites: cell signaling and ion transport ENSG00000167323 ENSG00000293604 ENSG00000139641 PMC7848762__F4 This network represents the interactions among the top-ranked genes participating in fusions in (A)T-cell acute lymphoblastic leukemia and (B) B-cell acute lymphoblastic leukemia ENSG00000118058 ENSG00000112576 ENSG00000151657 ENSG00000135363 ENSG00000166407 PMC8544255__F2 Deregulation of the canonical PI3K signalling pathway during CRC treatment ENSG00000033327 ENSG00000002330 ENSG00000109534 ENSG00000146648 PMC6781449__F10 Kindlin-3/leupaxin complex regulates paxillin tyrosine phosphorylation and podosome stability ENSG00000180210 ENSG00000117525 ENSG00000105370 PMC8544255__F1 Deregulation of the canonical MAPK signalling pathway during CRC treatment ENSG00000151657 ENSG00000157764 ENSG00000070831 ENSG00000115415 ENSG00000177606 ENSG00000136997 ENSG00000108443 PMC4702137__F8 Enhancement of hepatocyte differentiation from human embryonic stem cells by Chinese medicine Fuzhenghuayu ENSG00000168036 ENSG00000133961 PMC5028860__F1 Red nodes indicate the query proteins and the proteins present in the dotted circles, VTN, PRKACA, RELA, EP300, AKT1, EIF2C1, are the common proteins associated with the query proteins ENSG00000124422 ENSG00000135547 ENSG00000113140 ENSG00000173039 ENSG00000163453 ENSG00000112715 ENSG00000057663 ENSG00000133216 ENSG00000065978 ENSG00000101440 ENSG00000128052 ENSG00000115138 ENSG00000118257 ENSG00000172977 ENSG00000132275 PMC3985661__F8 Schematic representation of PARP1–TDP1 coupling for the repair of Top1–DNA covalent complexes ENSG00000143799 ENSG00000042088 PMC10390051__F3 Enteric nervous system as a target and source of SARS-CoV-2 and other viral infections ENSG00000130234 ENSG00000184012 ENSG00000154059 ENSG00000131095 PMC8774252__F2 Responsible Genes for Neuronal Migration in the Chromosome 17p13.3: Beyond Pafah1b1(Lis1), Crk and Ywhae(14-3-3E) ENSG00000166579 ENSG00000173406 PMC5427221__F1 Various roles of C3 in complement activation and effector functions ENSG00000186716 ENSG00000203710 ENSG00000117335 ENSG00000081051 ENSG00000117322 PMC8881125__F7 4-Octyl Itaconate Prevents Free Fatty Acid-Induced Lipid Metabolism Disorder through Activating Nrf2-AMPK Signaling Pathway in Hepatocytes ENSG00000079999 ENSG00000026103 PMC8843894__F2 Pathogenesis of premature coronary artery disease: Focus on risk factors and genetic variants ENSG00000162711 ENSG00000125538 ENSG00000132693 PMC5423858__F1 MicroRNA function in Drosophila memory formation ENSG00000101751 ENSG00000166169 ENSG00000132341 PMC7294616__F10 Anti-inflammatory signaling pathway mediated via OXA and OXR2 in ICH ENSG00000164830 PMC2925528__F1 Summary of the systemic involvement of choline-containing species and their potential relationship with inflammatory processes ENSG00000226275 ENSG00000173599 PMC1850660__F1 Summary of established Beta-catenin pathways ENSG00000134982 ENSG00000168036 PMC4755791__F3 Toward an Orofacial Gene Regulatory Network ENSG00000087510 ENSG00000158055 ENSG00000148400 ENSG00000008196 ENSG00000172818 ENSG00000175707 PMC3537922__F1 Unique host defense pathway: TRIF mediates both antiviral and antibacterial immune responses ENSG00000183735 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000110057 ENSG00000175104 ENSG00000164342 PMC8662335__F7 REC8 enhances stemness and promotes metastasis of colorectal cancer through BTK/Akt/Beta-catenin signaling pathway ENSG00000285007 ENSG00000168036 ENSG00000010671 PMC8650799__F3 Metabolic alterations reinforce pro- and anti-inflammatory macrophage phenotypes ENSG00000111537 ENSG00000125538 ENSG00000118520 PMC7164247__F8 Proposed model for antigen presentation by astrocytes in the PD brain PMC7858229__F1 Major forms of inflammatory cell death ENSG00000278718 ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000064012 ENSG00000164305 ENSG00000285379 PMC6357482__F6 Schema of miR-21 regulated PTEN, PDCD4, SPRY2 pathway ENSG00000136158 ENSG00000198670 PMC6357482__F8 Schema of miR-205 regulated ZEB1, ZEB2, EMT pathway ENSG00000169554 PMC9317057__F1 Transcriptional Regulation of the Hippo Pathway: Current Understanding and Insights from Single-Cell Technologies ENSG00000126016 ENSG00000186575 ENSG00000149930 ENSG00000160551 ENSG00000135090 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC9620778__F8 MAPK signaling pathway. The red nodes represent CN–NI-related genes ENSG00000142192 ENSG00000069482 ENSG00000170458 ENSG00000121058 ENSG00000256762 ENSG00000127191 ENSG00000026103 PMC9098816__F2 Reactive Oxygen Species Induce Fatty Liver and Ischemia-Reperfusion Injury by Promoting Inflammation and Cell Death ENSG00000189403 ENSG00000172936 PMC8948417__F4 RET receptor signaling: Function in development, metabolic disease, and cancer ENSG00000187871 ENSG00000130513 PMC8074527__F1 Mevalonate pathway involvement in viral mechanisms ENSG00000160752 ENSG00000143878 ENSG00000197429 PMC5777751__F6 Protein–protein interaction networks of differentially expressed proteins ENSG00000186810 ENSG00000291971 PMC3295657__F6 Pathway model for interleukin (IL)-1A and tumor necrosis factor (TNF)-Alpha-induced inhibition of human skeletal muscle cell (HuSKMC) differentiation PMC7285260__F6 N starvation and disruption of cyto-nuclear coadaptation on allantoin synthesis and degradation PMC7864210__F1 ERA:E2 signaling network and crosstalk with growth factor signaling ENSG00000291971 ENSG00000198793 PMC9104295__F3 Procyanidins and Their Therapeutic Potential against Oral Diseases ENSG00000002330 ENSG00000148400 ENSG00000198793 PMC8203325__F4 Targeting Signaling Pathway Networks in Several Malignant Tumors: Progresses and Challenges ENSG00000102871 ENSG00000172936 ENSG00000168040 ENSG00000127191 PMC8203325__F3 Targeting Signaling Pathway Networks in Several Malignant Tumors: Progresses and Challenges ENSG00000087245 ENSG00000140564 ENSG00000100985 PMC7081551__F1 Summary diagram of miRNAs, lncRNAs and circRNAs participated in the drug resistance of gastric cancer PMC5123688__F6 TLR8 couples SOCS-1 and restrains TLR7-mediated antiviral immunity exacerbating West Nile virus infection in mice ENSG00000164362 PMC6306791__F8 Possible molecular targets of the preventive effects of PT in Cr(VI)-induced ACD ENSG00000162711 ENSG00000125538 ENSG00000102977 PMC4479417__F10 PI3K-C2G is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling ENSG00000124102 ENSG00000157500 ENSG00000198793 PMC7996871__F2 PERK pathway and small molecule modulators ENSG00000128272 ENSG00000079999 PMC7996871__F1 Unfolded protein response (UPR) pathways ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 ENSG00000079999 PMC4013413__F2 Roles of ALK in the pathogenesis of ALK+ anaplastic large cell lymphoma (ALCL) ENSG00000143553 ENSG00000002330 ENSG00000291971 ENSG00000169047 ENSG00000198793 ENSG00000105639 ENSG00000168610 PMC11638488__F7 Mechanism of Trp in alleviating MS ENSG00000160867 ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC7772020__F1 Central metabolic regulation of ferroptosis ENSG00000196839 ENSG00000104549 PMC7782843__F1 Integrated molecular characterisation of the MAPK pathways in human cancers reveals pharmacologically vulnerable mutations and gene dependencies ENSG00000142192 ENSG00000284774 ENSG00000002330 ENSG00000157764 ENSG00000070831 ENSG00000291971 ENSG00000177606 ENSG00000136997 ENSG00000171791 ENSG00000127191 ENSG00000160691 PMC9468923__F5 Key player in the pathogenesis of environmental influence of systemic lupus erythematosus: Aryl hydrocarbon receptor ENSG00000198793 ENSG00000106546 PMC4643087__F3 Ingenuity pathway analysis (IPA) revealed a key role for the Molecular Mechanisms of Cancer set of pathways ENSG00000138795 ENSG00000002330 ENSG00000134982 ENSG00000169047 ENSG00000171791 ENSG00000168040 ENSG00000149311 ENSG00000110395 ENSG00000163914 ENSG00000173599 ENSG00000177606 ENSG00000136997 ENSG00000128602 ENSG00000080839 ENSG00000196712 PMC9468923__F1 Key player in the pathogenesis of environmental influence of systemic lupus erythematosus: Aryl hydrocarbon receptor ENSG00000106546 PMC4909418__F1 Smoothened-dependent and Forkhead box C1 transcription factor-induced Smoothened-independent Hedgehog signaling ENSG00000128602 PMC5973839__F1 Hyperglycemia enriches metabolic flux to glycolysis and five principal branches including the polyol pathway, pentose phosphate pathway (PPP), hexosamine pathway, protein kinase C (PKC) pathway, and advanced glycation end-products (AGE) pathway ENSG00000074800 ENSG00000140263 ENSG00000063854 PMC7936150__F6 Heme and protoporphyrin IX biosynthetic pathway ENSG00000066926 ENSG00000126088 ENSG00000188690 ENSG00000115657 PMC8107692__F6 Resistin-Like Molecule A Dysregulates Cardiac Bioenergetics in Neonatal Rat Cardiomyocytes ENSG00000117054 ENSG00000122971 PMC4122349__F2 Serum miRNA Signature in Moyamoya Disease ENSG00000198793 ENSG00000164327 PMC9686909__F2 Systematic Review of the Therapeutic Role of Apoptotic Inhibitors in Neurodegeneration and Their Potential Use in Schizophrenia ENSG00000168040 ENSG00000026103 PMC2666541__F1 (panel A) ODC expression is regulated by a number of signaling pathways ENSG00000134982 ENSG00000136997 PMC4478945__F8 Folate- and vitamin B-12–mediated one-carbon metabolism ENSG00000228716 ENSG00000065911 ENSG00000116984 PMC11726948__F8 Summary diagram of AGH treatment in mdx mice ENSG00000122180 ENSG00000150907 ENSG00000198947 PMC5308739__F3 Dihydroartemisinin suppresses pancreatic cancer cells via a microRNA-mRNA regulatory network ENSG00000117020 ENSG00000002330 ENSG00000163235 ENSG00000138798 ENSG00000006451 ENSG00000111816 PMC2901551__F1 mTOR signal pathway ENSG00000169047 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 ENSG00000186654 PMC8185338__F1 Autophagy as a Target for Drug Development Of Skin Infection Caused by Mycobacteria ENSG00000177169 ENSG00000083290 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000005893 PMC11816720__F3 Molecular mechanisms of kynurenine pathway in liver diseases ENSG00000087074 ENSG00000140465 ENSG00000106546 PMC12174442__F4 CO2-fixation metabolic pathways in autotrophic microorganisms ENSG00000131473 ENSG00000137996 PMC11816720__F1 Kynurenine pathway (KP) ENSG00000188676 PMC5479626__F7 Illustration of Hippo-p53 pathway in megakaryocytes (MKs) ENSG00000150457 PMC3731320__F1 Identification of Benzimidazole Diamides as Selective Inhibitors of the Nucleotide-Binding Oligomerization Domain 2 (NOD2) Signaling Pathway ENSG00000167207 PMC6262325__F1 Canonical hedgehog signaling pathway ENSG00000166813 ENSG00000128602 PMC2754444__F5 T-Cell Activation Pathways Generated by HIV-Modulated Proteins ENSG00000291603 ENSG00000110395 ENSG00000291971 ENSG00000015285 ENSG00000131910 ENSG00000099942 ENSG00000160691 PMC5597599__F2 Model Signaling Network PMC5597599__F1 Model Signaling Network PMC8632388__F7 Hyperlipidemia May Synergize with Hypomethylation in Establishing Trained Immunity and Promoting Inflammation in NASH and NAFLD ENSG00000131473 ENSG00000170899 ENSG00000162711 ENSG00000135218 ENSG00000198793 ENSG00000173599 ENSG00000136869 PMC9659888__F2 Noncoding RNA-mediated regulation of pyroptotic cell death in cancer ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000091592 PMC9659888__F1 Noncoding RNA-mediated regulation of pyroptotic cell death in cancer ENSG00000278718 ENSG00000162711 ENSG00000137275 ENSG00000125538 ENSG00000168040 ENSG00000168610 ENSG00000147697 ENSG00000073605 PMC11620901__F4 ACL injury management: a comprehensive review of novel biotherapeutics ENSG00000149269 ENSG00000138798 PMC3269300__F1 DN Tregs employ multiple mechanisms to exert antigen-specific control over immune responses ENSG00000111537 ENSG00000163599 PMC5738678__F1 Functional mechanism of the Notch signaling pathway ENSG00000128917 ENSG00000148400 ENSG00000074181 ENSG00000184916 ENSG00000090932 PMC7991918__F7 Targeted molecular and biological pathways’ interaction map analysis performed on the genes from the red module ENSG00000070087 ENSG00000133313 ENSG00000125249 ENSG00000028528 ENSG00000138071 ENSG00000196396 ENSG00000132639 ENSG00000101558 PMC8552375__F1 NAD+, Senolytics, or Pyruvate for Healthy Aging? ENSG00000173599 PMC8611496__F9 Noni on cellular viability and osteogenic differentiation of gingiva-derived stem cells demonstrated by RNA sequencing and quantitative PCR ENSG00000067141 ENSG00000111537 ENSG00000095739 ENSG00000187720 ENSG00000100387 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000164093 ENSG00000205250 ENSG00000137801 PMC3956536__F5 Heterogenic final cell cycle of chicken retinal Lim1 horizontal cells is not regulated by the DNA damage response pathway ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000134057 ENSG00000051180 PMC8417127__F2 Gut Microbiota in Lung Cancer: From Carcinogenesis to Immunotherapy ENSG00000115009 ENSG00000112486 PMC6081569__F10 Nuclear effects of DRD1/PKA pathway and reactive species on postsynaptic neurons ENSG00000125740 ENSG00000101751 PMC5892644__F6 Cycloartobiloxanthone Induces Human Lung Cancer Cell Apoptosis via Mitochondria-dependent Apoptotic Pathway ENSG00000171791 PMC8372480__F1 SARS-CoV-2 infection of islet B cells: Evidence and implications ENSG00000130234 ENSG00000184012 PMC7494909__F5 Intercalated disc protein XinB is required for Hippo-YAP signaling in the heart ENSG00000186575 ENSG00000170558 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC3421055__F3 IMPACT OF ALTERED METHYLATION IN CYTOKINE SIGNALING AND PROTEASOME FUNCTION IN ALCOHOL AND VIRAL-MEDIATED DISEASES ENSG00000173599 ENSG00000133027 PMC6416106__F2 Glutamine metabolism and macrophage polarization PMC9219854__F2 Importance and Value of Porcine Species in Sialic Acid Research ENSG00000064225 ENSG00000008513 ENSG00000111728 ENSG00000160408 ENSG00000070731 ENSG00000115525 ENSG00000126091 ENSG00000073849 ENSG00000095380 ENSG00000159921 ENSG00000170191 ENSG00000111726 ENSG00000101638 ENSG00000148488 ENSG00000070526 ENSG00000113532 ENSG00000144057 PMC5723588__F2 Haem synthetic pathway ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000188690 PMC6287190__F1 Classic and alternative pathways of bile acids synthesis ENSG00000276559 ENSG00000180432 ENSG00000135929 PMC4918816__F2 Comprehensive Review of Pacritinib in Myelofibrosis PMC6822144__F6 Schematic diagram showing role of Tbx15 on adipocyte browning and obesity ENSG00000142611 PMC6888001__F8 G Protein-Coupled Receptors (GPCRs)-Mediated Calcium Signaling in Ovarian Cancer: Focus on GPCRs activated by Neurotransmitters and Inflammation-Associated Molecules ENSG00000146648 ENSG00000150630 PMC6523352__F2 Heme activator proteins (HAP) complex ENSG00000006695 ENSG00000185608 ENSG00000039537 ENSG00000113600 ENSG00000179091 ENSG00000178741 ENSG00000166260 ENSG00000178449 ENSG00000174547 PMC9235271__F5 Metabolomics profile in acute respiratory distress syndrome by nuclear magnetic resonance spectroscopy in patients with community-acquired pneumonia ENSG00000122966 ENSG00000132693 ENSG00000163631 PMC8836080__F1 Genetics and Epigenetics of Bone Remodeling and Metabolic Bone Diseases ENSG00000281324 ENSG00000162337 ENSG00000134569 ENSG00000167941 ENSG00000106483 PMC4789259__F1 Canonical miRNA biogenesis pathway ENSG00000128191 ENSG00000113360 ENSG00000132341 PMC3099728__F8 Molecular model of Foxo1 and IGF1/insulin regulation of osteocalcin expression ENSG00000150907 PMC4026919__F1 Wnt signaling pathway ENSG00000134982 ENSG00000163914 ENSG00000168036 ENSG00000102678 PMC5294960__F1 Canonical and non-canonical TGFB signaling pathways ENSG00000198793 ENSG00000175104 ENSG00000135341 ENSG00000076604 PMC4695108__F3 Regulation of Bim in Health and Disease ENSG00000012048 ENSG00000116717 PMC4705949__F10 Proposed mechanism utilized by HDACi to inhibit osteoblast-mediated protection of AML cells ENSG00000109062 ENSG00000118898 PMC2648232__F6 Pathway mapping of OPC differentiation inducer genes ENSG00000133107 ENSG00000197971 ENSG00000143507 ENSG00000132535 PMC8742403__F9 ROS/PI3K/Akt and Wnt/Beta-catenin signalings activate HIF-1Alpha-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer ENSG00000074800 ENSG00000168036 ENSG00000159399 PMC3146023__F3 Human spermatogonial stem cells: a possible origin for spermatocytic seminoma PMC6297255__F8 Model proposing ROCK inhibition mediates morphological shift and neurite outgrowth-promoting property of OECs ENSG00000198910 PMC8188762__F2 SARS-CoV-2 plays a pivotal role in inducing hyperthyroidism of Graves’ disease ENSG00000042832 ENSG00000165409 PMC8375263__F1 One Gene, Many Facets: Multiple Immune Pathway Dysregulation in SOCS1 Haploinsufficiency ENSG00000172936 ENSG00000150455 PMC4230790__F3 Key signaling nodes in prostate cancer that regulate epithelial plasticity ENSG00000157554 ENSG00000170558 ENSG00000168036 ENSG00000120885 ENSG00000168610 ENSG00000146648 PMC9322748__F11 Differential Transcriptomic Profiles Following Stimulation with Lipopolysaccharide in Intestinal Organoids from Dogs with Inflammatory Bowel Disease and Intestinal Mast Cell Tumor ENSG00000276559 ENSG00000182240 PMC9207015__F1 Molecular mechanisms of Shigella effector proteins: a common pathogen among diarrheic pediatric population ENSG00000172936 ENSG00000157625 ENSG00000175104 PMC12010937__F7 Illustrated summary of the proposed roles of hepatic and intestinal FXR signaling pathways in TPHP-induced bile acid metabolic disorder and MASLD development in mice, based on the findings of this study ENSG00000167910 PMC4240281__F4 Molecular mechanisms of epithelial–mesenchymal transition ENSG00000175104 ENSG00000128602 ENSG00000168610 PMC3960720__F8 Q43L mutant of neuregulin 2B is a pan-ErbB receptor antagonist ENSG00000158458 ENSG00000146648 ENSG00000178568 PMC7275069__F3 FOXF2 acts as a crucial molecule in tumours and embryonic development ENSG00000137273 ENSG00000137491 ENSG00000156427 ENSG00000135903 ENSG00000134853 ENSG00000103241 ENSG00000164690 ENSG00000175104 ENSG00000168779 ENSG00000182606 ENSG00000127863 ENSG00000197461 PMC7275069__F2 FOXF2 acts as a crucial molecule in tumours and embryonic development ENSG00000100234 ENSG00000176692 ENSG00000137273 ENSG00000122691 ENSG00000168036 ENSG00000185591 ENSG00000150630 PMC8391356__F5 Galanin during Bacterial Infection in Larval Zebrafish ENSG00000182578 ENSG00000119535 ENSG00000198793 ENSG00000131095 ENSG00000103522 ENSG00000110324 ENSG00000177663 ENSG00000064300 ENSG00000145623 ENSG00000102245 ENSG00000113520 ENSG00000173578 ENSG00000131724 ENSG00000026103 ENSG00000016402 PMC3961843__F1 Selected glucose metabolic genes and their potential roles in tumor development ENSG00000147162 ENSG00000198380 ENSG00000159399 PMC4156617__F1 Updated working model for the AR showing a bifurcated signaling pathway downstream of cAMP/Epac PMC11083344__F4 BCAR3 in cell cycle progression ENSG00000070831 ENSG00000291971 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC7988727__F6 Prenatal indole-3-carbinol administration activates aryl hydrocarbon receptor-responsive genes and attenuates lung injury in a bronchopulmonary dysplasia model  ENSG00000102871 ENSG00000127191 PMC8203325__F2 Targeting Signaling Pathway Networks in Several Malignant Tumors: Progresses and Challenges PMC8203325__F1 Targeting Signaling Pathway Networks in Several Malignant Tumors: Progresses and Challenges ENSG00000162337 ENSG00000100592 ENSG00000134982 ENSG00000168036 PMC9051474__F2 Comparison of Metabolome and Functional Properties of Three Korean Cucumber Cultivars ENSG00000197429 PMC7483234__F3 Correlation of multiple markers of cell death signaling pathway in the hippocampal dentate gyrus (DG) of postmortem AUD human brain ENSG00000102871 ENSG00000215788 ENSG00000026103 PMC2570545__F2 EGFR signalling pathway in lipid rafts ENSG00000124102 ENSG00000002330 ENSG00000198793 ENSG00000173599 ENSG00000146648 PMC5712312__F1 Synthesis of glucosylceramide (GlcCer) and its complex glycoshingolipid metabolites ENSG00000069482 ENSG00000070610 ENSG00000188158 PMC8122946__F6 Gene Coexpression Network Analysis Indicates that Hub Genes Related to Photosynthesis and Starch Synthesis Modulate Salt Stress Tolerance in Ulmus pumila ENSG00000159224 PMC3432059__F6 Establishment of Mouse Teratocarcinomas Stem Cells Line and Screening Genes Responsible for Malignancy ENSG00000087095 ENSG00000134982 ENSG00000147869 ENSG00000113558 ENSG00000148175 ENSG00000196470 PMC8875122__F1 Fungal Colonization and Infections—Interactions with Other Human Diseases ENSG00000187796 ENSG00000198793 PMC6456212__F8 A carnosine analog with therapeutic potentials in the treatment of disorders related to oxidative stress ENSG00000142082 PMC6885086__F4 Effects of sulforaphane on Nrf2 and NFKB pathways ENSG00000175793 ENSG00000178573 ENSG00000079999 PMC7868022__F4 EBV-induced oncogenesis through the MAPK signaling pathway ENSG00000291431 ENSG00000138443 PMC7868022__F3 EBV-induced oncogenesis through the JAK/STAT signaling pathway ENSG00000153094 ENSG00000269404 ENSG00000165066 ENSG00000105639 ENSG00000168610 ENSG00000136630 PMC5108588__F8 Hypothetical model explaining the dysfunctional Wnt–Beta-catenin signaling in PPARG deficiency ENSG00000100744 ENSG00000171388 PMC5034935__F3 Proposed mechanisms by which the interaction of dietary long-chain n-3 polyunsaturated fatty acids from fish oil and butyrate from bacterial fermentation of dietary fiber may reduce colon tumorigenesis ENSG00000138794 ENSG00000164305 PMC7868022__F5 EBV-induced oncogenesis through the TGFB signaling pathway PMC7868022__F2 EBV-induced oncogenesis through the PI3K/AKT signaling pathway ENSG00000198793 ENSG00000168036 PMC3928694__F2 TLR signalling pathways: TLRs signal through myeloid differentiation primary response gene 88 (MyD88) or/and TIR-domain-containing adapter-inducing interferonB (TRIF)-dependent pathways ENSG00000174125 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC7868022__F1 EBV-induced oncogenesis through the NFKB signaling pathway ENSG00000113361 ENSG00000284764 ENSG00000168256 PMC12227979__F5 Exploring the Therapeutic Potential of Oxo berberine Compound in Arcangelisia flava Root Extract for Breast Cancer Treatment: Metabolite Profiling, Pharmacological Network Analysis, and In Silico and In Vitro Evaluation ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000183979 ENSG00000198793 ENSG00000127948 PMC4721599__F4 Network of genes located within high-level copy number changes and deregulated across all of the cell lines and tumors ENSG00000094804 ENSG00000156802 ENSG00000154553 ENSG00000130826 ENSG00000131747 ENSG00000136997 ENSG00000087586 ENSG00000112378 PMC6139685__F16 Tentative Model Explaining Redirection of Metabolism in the Absence of MDH2 during Photoautotrophic N Deprivation.FA degradation starts with hydrolysis of TAGs and membrane lipids by lipases ENSG00000172005 ENSG00000146701 ENSG00000026103 PMC6365454__F2 Chronic hyperglycemia impairs neuron function ENSG00000196689 PMC4979470__F1 The NLRP3 inflammasome signaling pathway ENSG00000162711 ENSG00000125538 PMC9183236__F9 Regulating alveolar formation through mitochondrial activity and distribution ENSG00000126858 ENSG00000108960 ENSG00000134853 ENSG00000197461 PMC6296439__F6 A model for the effect of JCAD CAD risk genotype on the Hippo signaling pathway ENSG00000163914 ENSG00000150457 ENSG00000165757 ENSG00000131023 PMC4288261__F2 N-terminal tyrosine residues of SLP-76 on the canonical TCR signaling pathway ENSG00000010810 ENSG00000177606 ENSG00000162924 ENSG00000113263 ENSG00000124181 PMC3126106__F3 Chemosensory processing in the taste – reward pathway ENSG00000104321 ENSG00000070985 ENSG00000137841 PMC4848008__F3 The HA/CD44 signaling pathway leading to the malignant phenotype of cancer cells ENSG00000026508 ENSG00000168610 PMC3248170__F1 Therapeutic Strategies to Overcome Acquired Resistance to BRAF or MEK Inhibitors in BRAF Mutant Cancers ENSG00000157764 ENSG00000140443 PMC4848008__F2 The hedgehog (Hh) signaling pathway and FAK cooperation with NANOG and p53 in the CSC phenotype ENSG00000117425 ENSG00000128602 PMC5341142__F2 Pharmacological targeting of the PDGF-CC signaling pathway for blood-brain barrier restoration in neurological disorders ENSG00000134853 ENSG00000185591 PMC7859453__F3 Activation of ERBB family receptors by growth factors can activate RAS MAPK signaling ENSG00000109321 ENSG00000124882 ENSG00000138798 ENSG00000163914 ENSG00000198670 PMC7859453__F2 MST activation center is the Hippo path ENSG00000186575 ENSG00000109321 ENSG00000124882 ENSG00000138798 PMC7859453__F1 MOB, RASSF, SAV scaffolding proteins play an essential role in activating the Hippo pathway ENSG00000129474 ENSG00000186575 ENSG00000109321 ENSG00000124882 ENSG00000138798 PMC7658374__F1 TGF beta SMAD-dependent signaling pathway ENSG00000121989 ENSG00000204217 PMC4062952__F1 Four androgen metabolism pathways to DHT synthesis ENSG00000151632 PMC6916680__F5 Suppression of proliferation and invasion and enhanced apoptosis of breast cancer cells by inhibition of expression of PI3K and its downstream signaling pathway by oxymatrine ENSG00000123374 ENSG00000100985 PMC10934115__F1 Genome-wide DNA methylation profiling identifies hypermethylated genes that are linked to regulation of multiple oncogenic signaling pathways in response to resveratrol (RSV) in breast cancer cells ENSG00000162552 ENSG00000117020 ENSG00000184384 ENSG00000198793 ENSG00000166501 ENSG00000197943 ENSG00000002745 ENSG00000164093 PMC10910747__F8 Working model: BMP9/BMP10/ALK1/SMAD4 Signaling drives the regulation of direct and indirect pathways in ECs ENSG00000157554 ENSG00000170365 ENSG00000137834 ENSG00000170961 ENSG00000135446 ENSG00000007908 ENSG00000073756 ENSG00000125968 ENSG00000163217 PMC4271587__F3 Flux map for accession 3231 (13C-MFA) ENSG00000122966 ENSG00000172005 PMC5964128__F3 Dex represses expression of phagosome formation-associated genes ENSG00000226275 ENSG00000172243 ENSG00000163914 PMC3606787__F8 Significant signaling pathway networks mined from nitroproteomic dataset ENSG00000144596 ENSG00000105329 ENSG00000100852 ENSG00000171791 ENSG00000185947 ENSG00000171055 ENSG00000159167 ENSG00000118508 ENSG00000170322 ENSG00000150991 ENSG00000168461 ENSG00000187017 ENSG00000112186 ENSG00000050405 ENSG00000104081 ENSG00000169851 ENSG00000167757 ENSG00000108960 ENSG00000288335 ENSG00000138594 ENSG00000131941 ENSG00000291973 ENSG00000105223 ENSG00000065609 ENSG00000134070 ENSG00000256646 PMC9476772__F10 Assessment of pulmonary infectious disease treatment with Mongolian medicine formulae based on data mining, network pharmacology and molecular docking ENSG00000142192 ENSG00000173039 ENSG00000174611 PMC9323014__F8 Runx2 in Microtubule Acetylation in Bone Metastatic Breast Cancer Cells ENSG00000094631 PMC3434621__F5 Interactions of Rex with host pathways, uncovered and covered ENSG00000067066 ENSG00000168036 ENSG00000126261 PMC3637685__F2 GAIT-mediated translational control ENSG00000163435 PMC2903975__F1 TLR signalling pathways: All TLRs except TLR3 share a common initial signalling pathway through MyD88 to the IRAK1/2/4TRAF6 complex ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC5845754__F10 Proposed model for Marf-mediated ER stress in FRDA flies PMC9448792__F8 Altered glucocorticoid receptor signaling in the diabetic proximal tubule ENSG00000124253 ENSG00000136872 PMC12128433__F7 Cbl-b inhibitor NX-1607 activates MAPK/ERK signaling pathway and enhances T-cell activation ENSG00000111537 ENSG00000134982 ENSG00000124181 PMC7427806__F5 New preclinical models for angioimmunoblastic T-cell lymphoma: filling the GAP ENSG00000104856 ENSG00000127191 PMC8487962__F1 Complement activation and its effects in periodontitis ENSG00000009724 ENSG00000291559 PMC2940266__F2 Phosphatase and Tensin Homologue deleted on Chromosome 10: Extending its PTENtacles ENSG00000002330 ENSG00000134982 ENSG00000168036 PMC2940266__F1 Phosphatase and Tensin Homologue deleted on Chromosome 10: Extending its PTENtacles ENSG00000002330 ENSG00000198793 ENSG00000105723 PMC7427806__F4 New preclinical models for angioimmunoblastic T-cell lymphoma: filling the GAP PMC5316546__F1 Our strategy to increase seed oil accumulation by overexpressing the plastidial pyruvate transporter BASS2 under the control of a seed-specific promoter in developing A ENSG00000173599 ENSG00000154258 ENSG00000026103 ENSG00000167701 PMC8349734__F5 Drug-repurposing against COVID-19 by targeting a key signaling pathway: An in silico study ENSG00000171791 PMC8349734__F4 Drug-repurposing against COVID-19 by targeting a key signaling pathway: An in silico study ENSG00000171791 ENSG00000026103 PMC11941171__F11 Mechanism of action of SJB2-043 in A549 cells ENSG00000198793 ENSG00000162607 ENSG00000168036 PMC7659166__F4 CeRNA network directly associated with hypertensive nephropathy ENSG00000117020 ENSG00000253352 PMC7188552__F2 Bile acid synthesis pathways ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC4475396__F1 REV7/MAD2L2: the multitasking maestro emerges as a barrier to recombination ENSG00000012048 ENSG00000116670 ENSG00000080345 ENSG00000134982 ENSG00000130997 ENSG00000117399 PMC6970952__F3 Pathview analysis of the EGFR tyrosine kinase inhibitor resistance signaling pathway ENSG00000167601 ENSG00000019991 ENSG00000002330 ENSG00000157764 ENSG00000138798 ENSG00000198793 ENSG00000171791 ENSG00000112715 ENSG00000121879 ENSG00000168610 ENSG00000160691 ENSG00000163235 ENSG00000134853 ENSG00000146648 ENSG00000140443 PMC7218056__F3 Hippo pathways in lymphocytes ENSG00000117525 ENSG00000150907 ENSG00000114978 ENSG00000205744 ENSG00000150457 ENSG00000131023 PMC4833475__F1 Insulin Signaling and Heart Failure ENSG00000140992 ENSG00000177169 ENSG00000135218 ENSG00000198793 ENSG00000169047 ENSG00000171791 PMC4243705__F4 CHROMOSOMAL INSTABILITY PATHWAY IN COLON CANCER ENSG00000183735 ENSG00000156299 ENSG00000163914 PMC10878151__F4 Phosphorylated SMAD2/3 signaling pathways regulate the process of HCC PMC10878151__F2 Crosstalk between TGF‑B/SMAD and other pathways ENSG00000198793 ENSG00000177606 PMC10878151__F1 Structure of the SMAD family and overview of TGFB/SMAD and BMP/SMAD signaling pathway ENSG00000170365 ENSG00000137834 PMC4389409__F2 Plant phytochemicals achieve hormesis through multifocal pathway inhibition ENSG00000198793 ENSG00000096717 PMC3996849__F3 Intestinal cholesterol absorption is a multistep process regulated by multiple genes ENSG00000138075 ENSG00000042832 ENSG00000138823 ENSG00000015520 ENSG00000113161 ENSG00000120437 ENSG00000143921 PMC11855393__F5 Targets of immunotherapy in triple-negative breast cancer (TNBC) ENSG00000089692 ENSG00000181847 PMC11855393__F4 EGFR, FGFR, PI3K and MEK pathways and their potential inhibitors in triple-negative breast cancer (TNBC) ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC3270101__F6 Pathway map related to cisplatin-induced hepatotoxicity based on proteomic and genomic analysis ENSG00000081181 ENSG00000138823 ENSG00000169710 ENSG00000277897 ENSG00000118520 ENSG00000146701 ENSG00000065802 PMC11855393__F3 Cancer stem cell-associated pathways and their potential inhibitors in triple-negative breast cancer (TNBC) ENSG00000122882 ENSG00000281324 ENSG00000162337 ENSG00000112655 ENSG00000168036 ENSG00000168610 PMC11855393__F2 AR and associated pathways and their potential inhibitors in triple-negative breast cancer (TNBC) ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC8403114__F2 Genetic Epidemiology of Joint Shape and the Development of Osteoarthritis ENSG00000125398 ENSG00000260428 ENSG00000163501 PMC8355560__F2 An Overview of Novel Agents for Cervical Cancer Treatment by Inducing Apoptosis: Emerging Drugs Ongoing Clinical Trials and Preclinical Studies ENSG00000149311 ENSG00000090402 ENSG00000118785 ENSG00000148400 ENSG00000198793 ENSG00000189403 ENSG00000168610 ENSG00000146648 ENSG00000095002 ENSG00000026103 PMC7352566__F1 DNA Double Strand Break repair by Homologous Recombination or Non-Homologous End-Joining pathway ENSG00000012048 ENSG00000080345 ENSG00000253251 ENSG00000122376 ENSG00000051180 ENSG00000139618 PMC7284830__F1 Examined genetic variants involved in folate and vitamin D metabolic pathways ENSG00000228716 ENSG00000100714 ENSG00000124275 ENSG00000035928 ENSG00000116984 PMC9356005__F3 Underlying mechanism of Treg in skeletal muscle repair and regeneration ENSG00000108691 ENSG00000137033 ENSG00000109321 PMC8617942__F2 Mechanisms Driving Palmitate-Mediated Neuronal Dysregulation in the Hypothalamus ENSG00000115138 ENSG00000168610 PMC8617942__F1 Mechanisms Driving Palmitate-Mediated Neuronal Dysregulation in the Hypothalamus ENSG00000171105 ENSG00000150907 ENSG00000198793 ENSG00000115138 PMC3904668__F1 CD180 is a close relative of TLR4 and together with BCR signaling can promote B-cell activation and differentiation ENSG00000186716 ENSG00000172936 ENSG00000136869 ENSG00000134061 ENSG00000141968 PMC3626870__F4 Arsenic-mediated disruption of PI3K/AKT signaling pathway ENSG00000002330 ENSG00000070831 ENSG00000198793 PMC6934036__F5 Inhibitors used for antitumoral therapy ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000136997 ENSG00000058091 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC9929774__F5 Bioinformatics analysis of differentially expressed genes in diabetic foot ulcer and preliminary experimental verification ENSG00000145604 ENSG00000149311 ENSG00000087095 ENSG00000171105 ENSG00000127528 PMC7045974__F2 Differential dependency network focused on the KEGG apoptosis pathway () ENSG00000149311 ENSG00000002330 ENSG00000102871 ENSG00000138794 ENSG00000172936 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC12080384__F2 Mode of action of non-coding RNAs in tumors ENSG00000185591 ENSG00000168610 PMC12080384__F4 Multifaceted roles of RBP-regulated non-coding RNAs in tumors ENSG00000142892 ENSG00000186575 ENSG00000119707 ENSG00000072274 ENSG00000136997 ENSG00000162191 ENSG00000092199 ENSG00000168610 ENSG00000131023 ENSG00000100320 ENSG00000113360 PMC3350990__F2 Bioinformatic analysis of the differentially expressed proteins.The list of the MS-identified protein spots from 2D-DIGE was subjected to String (v ENSG00000108861 ENSG00000138757 ENSG00000132535 PMC3253915__F2 Innovative Therapy for Classic Galactosemia - Tale of Two HTS ENSG00000138798 ENSG00000146648 PMC12114667__F1 CK1E’s role in the Wnt/Beta-catenin signaling pathway ENSG00000124216 ENSG00000163032 ENSG00000089685 ENSG00000134982 ENSG00000136997 ENSG00000019549 ENSG00000168036 PMC4802755__F1 Schematic depiction on exogenous LIF mediated intra-cellular signaling pathways for robust self-renewal in mESCs ENSG00000128342 ENSG00000168610 PMC8349295__F7 Bilirubin Oxidation End Products (BOXes) Induce Neuronal Oxidative Stress Involving the Nrf2 Pathway ENSG00000174156 ENSG00000079999 PMC7432680__F1 Rewiring of Lipid Metabolism in Adipose Tissue Macrophages in Obesity: Impact on Insulin Resistance and Type 2 Diabetes ENSG00000149311 ENSG00000135218 ENSG00000042832 ENSG00000136869 ENSG00000160179 ENSG00000026103 PMC7985688__F6 Illustrative model of the mechanism underlying the neuroprotective effects of PROG and ALLO against ketamine-induced cognitive deficits ENSG00000146648 PMC8332860__F8 Doxycycline potentiates the anti-proliferation effects of gemcitabine in pancreatic cancer cells ENSG00000188486 ENSG00000134042 ENSG00000099985 ENSG00000137033 ENSG00000136869 ENSG00000168040 ENSG00000127948 ENSG00000164342 ENSG00000164949 PMC9322447__F3 Fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2 ENSG00000087245 PMC8332860__F7 Doxycycline potentiates the anti-proliferation effects of gemcitabine in pancreatic cancer cells ENSG00000177455 ENSG00000149089 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000127948 ENSG00000164949 PMC8332860__F6 Doxycycline potentiates the anti-proliferation effects of gemcitabine in pancreatic cancer cells ENSG00000172680 ENSG00000002330 ENSG00000143839 ENSG00000168040 ENSG00000180210 ENSG00000175054 ENSG00000110395 ENSG00000049130 ENSG00000198670 ENSG00000128602 ENSG00000127948 ENSG00000164949 ENSG00000084774 ENSG00000167419 PMC4074825__F3 FHIT-substrate complex as a signaling molecule ENSG00000189283 ENSG00000291971 ENSG00000138798 PMC6826306__F6 Pathway enrichment analysis of genes with eQTL associations with identified disease-associated SNPs ENSG00000064490 ENSG00000291603 ENSG00000135218 ENSG00000147168 ENSG00000196839 ENSG00000232326 ENSG00000105656 ENSG00000175097 ENSG00000010671 ENSG00000177455 ENSG00000095585 ENSG00000160224 ENSG00000293604 ENSG00000133111 PMC10944245__F10 Cytotoxic effect of flavonoids resulted from nuclear factor erythroid 2 (Nerf-2), Ak strain transforming (Akt), and nuclear factor kappa B (NFƙB) pathways ENSG00000172936 ENSG00000079999 PMC4338832__F2 Drug targets in the autophagic pathway to treat human cancers ENSG00000177169 PMC6842984__F1 Diagrammatic representation of known mechanisms of action of lithium in endocrine cancers ENSG00000168036 ENSG00000171791 PMC8027318__F2 Proposed model of signaling crosstalk for the BCR to induce CSR ENSG00000104856 ENSG00000186716 ENSG00000173039 ENSG00000197943 ENSG00000172936 ENSG00000131323 ENSG00000127191 ENSG00000010671 PMC7058824__F1 Vitamin D Metabolic Pathway ENSG00000111012 ENSG00000172893 ENSG00000145321 ENSG00000186104 PMC9267050__F2 Therapeutic Potential of the Restoration of the p53 Protein Family Members in the EGFR-Mutated Lung Cancer ENSG00000146648 PMC7056731__F5 Interplays between Hippo signaling and ROS production ENSG00000174125 ENSG00000172936 ENSG00000136869 ENSG00000150457 ENSG00000127191 ENSG00000131023 ENSG00000184216 ENSG00000079999 PMC8083902__F2 Relationship Between Autophagy and Metabolic Syndrome Characteristics in the Pathogenesis of Atherosclerosis ENSG00000042832 ENSG00000158828 PMC8585639__F6 Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets ENSG00000278718 ENSG00000162711 ENSG00000130234 ENSG00000125538 ENSG00000285379 PMC7056731__F2 Reciprocal augment of Hippo-YAP signaling and innate antiviral response ENSG00000213928 ENSG00000150457 ENSG00000131023 ENSG00000142166 ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000134070 ENSG00000131323 ENSG00000184216 ENSG00000164342 PMC8001359__F9 ISL effect on TGFB1 induced epithelial-mesenchymal transition (EMT) in human endometrial cancer ENSG00000105329 ENSG00000170558 PMC7056731__F1 Simple scheme of the Hippo pathway in mammalian cells ENSG00000186575 ENSG00000138798 ENSG00000150457 ENSG00000131023 PMC8585639__F4 Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets ENSG00000137275 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC7056731__F4 Crosstalk between Hippo-YAP pathway and NFKB signaling ENSG00000174125 ENSG00000081041 ENSG00000102871 ENSG00000163739 ENSG00000150457 ENSG00000127191 ENSG00000131023 ENSG00000163702 ENSG00000239732 ENSG00000187554 ENSG00000082512 ENSG00000136869 ENSG00000157625 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC7056731__F3 Mutual activation of Hippo-Yorkie pathway and Toll/IMD mediated anti-bacterial response in Drosophila ENSG00000172936 ENSG00000168040 PMC5037084__F1 Molecular mechanisms contributing to liver steatosis following hepatitis B virus infection ENSG00000042832 ENSG00000099194 ENSG00000026103 PMC12034938__F8 Plantamajoside Promotes NGF/TrkA Pathway to Inhibit Neuronal Apoptosis and Improve Diabetic Peripheral Neuropathy ENSG00000171791 PMC7226887__F1 Role of PTEN in the control of cell signaling ENSG00000002330 ENSG00000096717 ENSG00000026103 PMC6260831__F2 Deregulated Signaling Networks in Pancreatic Cancer ENSG00000157764 ENSG00000134982 ENSG00000198793 ENSG00000197905 ENSG00000114978 ENSG00000168036 ENSG00000007866 ENSG00000131023 ENSG00000168610 ENSG00000074219 ENSG00000135446 ENSG00000105810 ENSG00000196712 PMC11124422__F3 APS on ICIs, CAR-T therapy, and DC cancer vaccines within the TME ENSG00000198793 PMC6771966__F1 Mutual interactions of the mitochondrial compartment with hepatitis viruses and the consequences on the infections ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000111537 ENSG00000276561 PMC11124422__F2 Mechanism by which APS induces apoptosis in cancer cells by interfering with the cell cycle, inhibiting signal transduction pathways, and inducing apoptosis ENSG00000135446 ENSG00000198793 ENSG00000173039 ENSG00000168036 ENSG00000172936 ENSG00000136869 ENSG00000105810 ENSG00000150455 ENSG00000175104 ENSG00000168610 ENSG00000076604 PMC9144176__F1 Targeting Membrane Trafficking as a Strategy for Cancer Treatment ENSG00000168036 PMC9469619__F1 Emerging role of non-coding RNAs in the regulation of Sonic Hedgehog signaling pathway ENSG00000106571 ENSG00000166813 ENSG00000288335 ENSG00000164690 ENSG00000128602 PMC9469619__F2 Emerging role of non-coding RNAs in the regulation of Sonic Hedgehog signaling pathway ENSG00000064309 ENSG00000106571 ENSG00000144857 ENSG00000166813 ENSG00000136997 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 ENSG00000150630 PMC8714827__F2 EGFR-Dependent Extracellular Matrix Protein Interactions Might Light a Candle in Cell Behavior of Non-Small Cell Lung Cancer ENSG00000138798 ENSG00000198793 ENSG00000140092 ENSG00000146648 PMC7000168__F1 Summary of myocardial cellular effects and the injury response induced by doxorubicin ENSG00000102908 ENSG00000285109 ENSG00000198793 ENSG00000136869 ENSG00000164305 ENSG00000139618 ENSG00000026103 PMC1783401__F6 Integration of Runx1 and the BMP signaling pathway into the SCL transcriptional network ENSG00000157554 ENSG00000170365 ENSG00000137834 ENSG00000159216 ENSG00000179348 PMC8714827__F3 EGFR-Dependent Extracellular Matrix Protein Interactions Might Light a Candle in Cell Behavior of Non-Small Cell Lung Cancer ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000172936 ENSG00000146648 PMC8305424__F3A Genomic Approach to Delineating the Occurrence of Scoliosis in Arthrogryposis Multiplex Congenita ENSG00000038382 ENSG00000172380 ENSG00000175866 ENSG00000070831 ENSG00000134982 ENSG00000138798 ENSG00000089159 PMC7334043__F2 Primary metabolic pathways of R ENSG00000067064 ENSG00000065833 ENSG00000100412 ENSG00000157911 ENSG00000198670 ENSG00000146701 ENSG00000138356 PMC8613465__F2 Signaling pathways and intervention therapies in sepsis ENSG00000278718 ENSG00000163568 ENSG00000198793 ENSG00000158828 ENSG00000189403 ENSG00000136869 ENSG00000285069 PMC6155173__F5 RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation ENSG00000137275 ENSG00000102871 ENSG00000136869 ENSG00000168404 ENSG00000285379 ENSG00000164342 PMC8613465__F1 Signaling pathways and intervention therapies in sepsis ENSG00000278718 ENSG00000150782 ENSG00000183735 ENSG00000164430 ENSG00000167468 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000265972 ENSG00000146648 PMC8613465__F3 Signaling pathways and intervention therapies in sepsis ENSG00000003436 ENSG00000134982 ENSG00000127528 ENSG00000187266 PMC4427301__F4 Downregulation of Notch Signaling Pathway in Late Preterm and Term Placentas from Pregnancies Complicated by Preeclampsia ENSG00000135547 ENSG00000128917 ENSG00000074181 ENSG00000184916 ENSG00000090932 PMC8516728__F2 Triumvirate of NFKB, inflammation and cytokine storm in COVID-19 ENSG00000213928 ENSG00000102871 ENSG00000130234 ENSG00000184012 ENSG00000168610 ENSG00000276561 ENSG00000164342 PMC8516728__F1 Triumvirate of NFKB, inflammation and cytokine storm in COVID-19 ENSG00000104856 PMC6784827__F1 Schematic presentation of mechanotransduction and inflammasome signaling ENSG00000162711 ENSG00000163568 ENSG00000123143 ENSG00000065243 PMC5882306__F7 Transcriptome and proteome profiling reveals stress-induced expression signatures of imiquimod-treated Tasmanian devil facial tumor disease (DFTD) cells ENSG00000132906 ENSG00000291983 ENSG00000128272 ENSG00000144895 ENSG00000171791 ENSG00000164305 PMC5882306__F5 Transcriptome and proteome profiling reveals stress-induced expression signatures of imiquimod-treated Tasmanian devil facial tumor disease (DFTD) cells ENSG00000094804 ENSG00000167513 ENSG00000115942 ENSG00000135336 ENSG00000091651 ENSG00000093009 PMC5606087__F8 Connection among hub genes predicted on KEGG pathways ENSG00000126016 ENSG00000170027 PMC3646763__F7 Beyond the Binding Site: In Vivo Identification of tbx2, smarca5 and wnt5b as Molecular Targets of CNBP during Embryonic Development ENSG00000070814 ENSG00000153147 ENSG00000111186 PMC5882306__F4 Transcriptome and proteome profiling reveals stress-induced expression signatures of imiquimod-treated Tasmanian devil facial tumor disease (DFTD) cells ENSG00000087095 ENSG00000002330 ENSG00000042832 ENSG00000291971 ENSG00000064393 ENSG00000132478 ENSG00000168040 ENSG00000185010 ENSG00000149311 ENSG00000175054 ENSG00000110395 ENSG00000148204 ENSG00000177606 ENSG00000136997 ENSG00000080839 PMC5882306__F3 Transcriptome and proteome profiling reveals stress-induced expression signatures of imiquimod-treated Tasmanian devil facial tumor disease (DFTD) cells ENSG00000159224 ENSG00000128272 ENSG00000159461 ENSG00000165280 ENSG00000127022 ENSG00000100219 ENSG00000171791 ENSG00000127191 PMC3684427__F5 The regulation of clot formation (colored entities) ENSG00000003436 ENSG00000134982 PMC3841024__F4 Representative ingenuity pathway analysis (IPA) of relationship between significant genes involved in the response to mechanical stretch and/or BIRB796 treatment in engineered cardiac tissues ENSG00000170962 ENSG00000124882 ENSG00000175592 ENSG00000110680 ENSG00000073756 ENSG00000115461 PMC8480435__F2 Example of oncogenic signaling and downstream metabolic and physiologic imaging changes during molecular therapies ENSG00000136997 PMC8300228__F2 Antimicrobial Peptides from Black Soldier Fly (Hermetia illucens) as Potential Antimicrobial Factors Representing an Alternative to Antibiotics in Livestock Farming ENSG00000172936 ENSG00000168040 PMC5858852__F7 Pathways enriched for genes associated with ovarian cancer ENSG00000123975 ENSG00000086696 ENSG00000137673 ENSG00000248144 ENSG00000135069 ENSG00000171517 ENSG00000104332 ENSG00000116039 ENSG00000102678 ENSG00000178445 ENSG00000138356 ENSG00000147408 ENSG00000164736 ENSG00000095739 ENSG00000144644 ENSG00000134245 PMC6518377__F1 The old dog ENSG00000115138 ENSG00000166603 PMC4449096__F1 Signaling pathways through which macrophages regulate Beta-cell replication ENSG00000138798 ENSG00000168036 ENSG00000146648 PMC2697617__F1 Live Longer Sans the AT1A Receptor ENSG00000138798 ENSG00000169047 ENSG00000198793 ENSG00000146648 PMC3142910__F5 Schematic representation showing proposed role of TMPRSS6 regulation by the BMP6-SMAD signaling pathway and iron via ID1 ENSG00000170365 ENSG00000010704 ENSG00000187045 ENSG00000125968 PMC3280674__F1 Fatty Heart, Cardiac Damage, and Inflammation ENSG00000135218 ENSG00000042832 PMC5149523__F3 PD-1/PD-L1 blockade enhances tumor rejection by activating T cells ENSG00000213658 ENSG00000198793 PMC2694804__F2 Summary of the pathways transduced by the primary cilium ENSG00000134853 ENSG00000164690 ENSG00000128602 ENSG00000197461 PMC5149523__F1 Effect of PD-1 on major signaling pathways and subsequent metabolic reprograming in T cells ENSG00000213658 ENSG00000134982 ENSG00000198793 PMC2864762__F13 CFTR Depletion Results in Changes in Fatty Acid Composition and Promotes Lipogenesis in Intestinal Caco 2/15 Cells ENSG00000042832 PMC4851838__F1 Recurrent genetic alterations and targeted therapies under investigation in iCCA ENSG00000117713 ENSG00000066468 ENSG00000163930 ENSG00000138798 ENSG00000198793 ENSG00000105810 ENSG00000047936 ENSG00000146648 PMC10143509__F3 Involvement of p53 in activation of interferon genes, of interferon-stimulated genes, and in feedback loops regulating these processes ENSG00000213928 ENSG00000122694 ENSG00000187608 ENSG00000157601 ENSG00000115267 ENSG00000185745 ENSG00000276561 ENSG00000178685 ENSG00000281614 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 PMC8913072__F8 Cyclic Polypeptide D7 Protects Bone Marrow Mesenchymal Cells and Promotes Chondrogenesis during Osteonecrosis of the Femoral Head via Growth Differentiation Factor 15-Mediated Redox Signaling ENSG00000139219 ENSG00000125398 ENSG00000198793 ENSG00000171791 ENSG00000130513 PMC6776190__F10 Kyoto Encyclopedia of Genes and Genomes pathway analysis in SK-BR-3 vs ENSG00000043355 ENSG00000180447 ENSG00000112210 ENSG00000128602 PMC9115561__F2 RNA Therapeutic Options to Manage Aberrant Signaling Pathways in Hepatocellular Carcinoma: Dream or Reality? ENSG00000108691 ENSG00000089685 ENSG00000188042 ENSG00000198793 ENSG00000136997 ENSG00000164362 ENSG00000168036 ENSG00000121807 ENSG00000146648 ENSG00000121966 PMC8436520__F1 Phenotypic and immune functional profiling of patients with suspected Mendelian Susceptibility to Mycobacterial Disease in South Africa ENSG00000096996 ENSG00000138378 ENSG00000187608 ENSG00000105397 ENSG00000115415 ENSG00000140968 PMC5210527__F4 Insulin signaling pathway is significantly enriched in human cycling genes (the hypergeometric test, p-value = 9.70E-7, E-ratio = 2.26) ENSG00000171105 ENSG00000110395 ENSG00000005882 ENSG00000150907 ENSG00000198793 ENSG00000026103 PMC8141194__F1 Non-coding RNAs modulate autophagy in myocardial ischemia-reperfusion injury: a systematic review ENSG00000198793 ENSG00000144848 ENSG00000057663 PMC6196657__F1 Expression and regulation of hepcidin in brain cells ENSG00000105697 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC3404846__F1 Mechanism of the tandem DRA/N-Boc protection proposed in this study based on the known pathway ENSG00000144857 PMC5216829__F1 Relationship between hypoxia and response to antiangiogenic therapy in metastatic colorectal cancer ENSG00000157404 ENSG00000198793 PMC5594543__F4 Influence of PM10 exposure on coagulation ENSG00000180210 ENSG00000173599 ENSG00000080618 ENSG00000122194 PMC9133800__F3 Biological nitrogen fixation and prospects for ecological intensification in cereal-based cropping systems ENSG00000135838 ENSG00000136997 PMC4985183__F6 Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer ENSG00000143799 ENSG00000005339 ENSG00000134982 ENSG00000126883 ENSG00000168036 ENSG00000166508 ENSG00000149311 ENSG00000103479 ENSG00000198176 ENSG00000136997 ENSG00000149273 ENSG00000132383 ENSG00000167670 ENSG00000123374 ENSG00000196498 ENSG00000139687 ENSG00000140464 ENSG00000253729 ENSG00000111642 ENSG00000100603 ENSG00000130726 PMC4985183__F5 Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer ENSG00000172613 ENSG00000134982 ENSG00000168036 ENSG00000197442 ENSG00000166508 ENSG00000183765 ENSG00000103479 ENSG00000079246 ENSG00000136997 ENSG00000132383 ENSG00000123374 ENSG00000196498 ENSG00000177084 ENSG00000139687 ENSG00000140464 ENSG00000253729 ENSG00000198947 ENSG00000100603 ENSG00000005339 ENSG00000101057 ENSG00000126883 ENSG00000149311 ENSG00000198176 ENSG00000162409 ENSG00000146648 ENSG00000130726 PMC3774688__F1 Helicopter Perspective on TB Biomarkers: Pathway and Process Based Analysis of Gene Expression Data Provides New Insight into TB Pathogenesis ENSG00000071575 ENSG00000105664 ENSG00000108691 ENSG00000081041 ENSG00000033327 ENSG00000105835 ENSG00000213658 ENSG00000081237 ENSG00000291971 ENSG00000138071 ENSG00000132185 ENSG00000273936 PMC4985183__F3 Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer ENSG00000143799 ENSG00000092201 ENSG00000284774 ENSG00000134982 ENSG00000164190 ENSG00000168036 ENSG00000073111 ENSG00000162302 ENSG00000076003 ENSG00000166508 ENSG00000179295 ENSG00000165684 ENSG00000101945 ENSG00000079246 ENSG00000033030 ENSG00000136997 ENSG00000132383 ENSG00000167670 ENSG00000122565 ENSG00000177084 ENSG00000139687 ENSG00000140464 ENSG00000253729 ENSG00000198947 ENSG00000100603 ENSG00000005339 ENSG00000198648 ENSG00000101057 ENSG00000033800 ENSG00000163902 ENSG00000126883 ENSG00000162924 ENSG00000131023 ENSG00000149311 ENSG00000162409 ENSG00000165392 ENSG00000164754 ENSG00000122779 ENSG00000146648 ENSG00000130726 ENSG00000141456 ENSG00000111642 PMC8524440__F2 Applications of Magnetite Nanoparticles in Cancer Immunotherapies: Present Hallmarks and Future Perspectives ENSG00000163599 PMC8145606__F11 Anti-Tumor Effect and Mechanism of Triterpenoids in Rhus chinensis Mill. on Reversing Effector CD8+ T-cells Dysfunction by Targeting Glycolysis Pathways in Colorectal Cancer ENSG00000111537 ENSG00000134982 ENSG00000173611 ENSG00000198793 ENSG00000026103 PMC6691976__F1 Metabolic pathways regulated during T cell differentiation ENSG00000136997 ENSG00000113161 ENSG00000169710 ENSG00000198670 ENSG00000175104 PMC5541251__F6 Illustration of AHR activity in pituitary cells ENSG00000110711 ENSG00000140465 ENSG00000124762 ENSG00000106546 PMC5806108__F3 Upstream cell signaling pathway of autophagy ENSG00000198793 PMC7886651__F1 Revisiting the role of CD4+ T cells in cancer immunotherapy—new insights into old paradigms ENSG00000111537 ENSG00000115415 ENSG00000137265 ENSG00000107485 ENSG00000049768 ENSG00000168610 PMC5806108__F1 NSAIDs significantly induce autophagy ENSG00000019991 ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC7139730__F3 The autophagy-induced anti-HCC polyphenols signaling pathways ENSG00000177169 ENSG00000126775 PMC3114309__F1 The NFAT structure ENSG00000185591 ENSG00000167182 PMC7139730__F1 Major cell death pathways: Apoptosis, autophagy, and necroptosis ENSG00000102871 ENSG00000120868 ENSG00000168040 ENSG00000168404 ENSG00000145782 ENSG00000285379 PMC3613096__F2 Signalling pathways involved in airway smooth muscle contraction ENSG00000086991 PMC7493323__F1 CX3CR1/ Fractalkine signalling—different roles in Microglia: In Alzheimer’s disease, chronic neuroinflammation increases the pro-inflammatory stimuli such as LPS, TNFA and IL-6 in the CNS ENSG00000168329 ENSG00000084093 ENSG00000159335 PMC4515126__F1 Sirt1 controls the immune responses in macrophages ENSG00000105835 ENSG00000077463 ENSG00000096717 PMC9535406__F5 Role of TGFΒ and autophagy in early crebellum development ENSG00000170558 ENSG00000149294 ENSG00000168036 ENSG00000150394 PMC8347150__F3 Impact of Hypoxia over Human Viral Infections and Key Cellular Processes ENSG00000086102 ENSG00000198793 ENSG00000163914 PMC8347150__F2 Impact of Hypoxia over Human Viral Infections and Key Cellular Processes ENSG00000180210 ENSG00000169710 PMC7642368__F5 Airway neutrophils are activated in intubated children with compared to children without PARDS ENSG00000135404 ENSG00000213694 ENSG00000005381 PMC3726753__F2 Morphoproteomic Profiling of the Mammalian Target of Rapamycin (mTOR) Signaling Pathway in Desmoplastic Small Round Cell Tumor (EWS/WT1), Ewing’s Sarcoma (EWS/FLI1) and Wilms’ Tumor(WT1) ENSG00000151702 ENSG00000198793 ENSG00000164327 ENSG00000167965 ENSG00000146648 ENSG00000140443 PMC3039931__F1 Cytoplasmic tyrosine kinases in the activating signaling pathways utilizing ITAM-containing adapters ENSG00000163914 ENSG00000135605 PMC8743650__F1 Mitochondrial dynamics and diabetic kidney disease: Missing pieces for the puzzle of therapeutic approaches ENSG00000100253 ENSG00000168958 ENSG00000116688 ENSG00000158828 ENSG00000067900 ENSG00000171109 PMC4301880__F1 Experimental design ENSG00000069943 ENSG00000000419 ENSG00000100564 ENSG00000197563 ENSG00000185808 ENSG00000129255 ENSG00000165282 ENSG00000275600 ENSG00000142892 ENSG00000143315 ENSG00000163964 ENSG00000108474 ENSG00000060642 ENSG00000101464 ENSG00000124155 ENSG00000148985 ENSG00000197858 ENSG00000136908 PMC3039931__F3 Inhibitory pathways in innate cells utilizing ITIM or “inhibitory” ITAM signaling pathways ENSG00000198053 ENSG00000163914 ENSG00000135605 PMC5275769__F4 miRNAs enriched with OSCC target mRNAs of the neurotrophin signaling pathway ENSG00000169291 ENSG00000157764 ENSG00000177606 ENSG00000173039 PMC4671616__F7 TGFB Controls miR-181/ERK Regulatory Network during Retinal Axon Specification and Growth ENSG00000198742 ENSG00000113360 PMC3039931__F2 Tyrosine kinase pathways leading to CARD9 and TLR signaling responses ENSG00000187796 ENSG00000172936 ENSG00000135605 PMC7161517__F3 Renin-Angiotensin System Interaction With COVID-19Normally, angiotensin I (Ang I) is converted to Ang II via angiotensin-converting enzyme (ACE), which could be inhibited by ACE inhibitors ENSG00000130234 PMC7950759__F3 Smurf ubiquitin ligase activity and protein levels in cancers ENSG00000126457 ENSG00000076604 PMC6330595__F1 Graphical representation of glutamine/2-HG pathway and therapeutics options in renal cancer based on Shelar et al ENSG00000087299 ENSG00000180902 PMC6611700__F1 Outside-in and inside-out signal transduction in myofibroblastic activation PMC10143579__F1 Brain Kynurenine Pathway Metabolite Levels May Reflect Extent of Neuroinflammation in ALS, FTD and Early Onset AD PMC3769666__F1 Extrinsic and intrinsic apoptotic pathways ENSG00000102871 PMC3382265__F1 Molecular network of protein degradation, amino acid metabolism, and behavior for NC-treated cells in comparison with TC extract-treated cells ENSG00000146950 ENSG00000123416 ENSG00000033327 ENSG00000244486 ENSG00000170027 ENSG00000172725 ENSG00000115263 ENSG00000099942 PMC7234984__F1 Cross-disorder genetic analyses implicate dopaminergic signaling as a biological link between Attention-Deficit/Hyperactivity Disorder and obesity measures ENSG00000133275 ENSG00000073711 ENSG00000154415 ENSG00000115896 PMC5819875__F2 Wnt/Beta-catenin signaling during early vertebrate neural development ENSG00000204335 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000136997 ENSG00000102312 ENSG00000168036 ENSG00000167074 PMC6857659__F1 TGFB signaling pathway and its role in tumor immune microenvironment ENSG00000102962 ENSG00000172936 ENSG00000049768 ENSG00000125968 PMC1885790__F3 Diagram illustrating how the Rb and p53 pathways are linked to form a complex tumor suppressor network ENSG00000135446 ENSG00000136997 PMC11125669__F1 Pattern recognition receptors (PRRs) involved in intracellular viral sensing and downstream signaling ENSG00000183735 ENSG00000213928 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000115415 ENSG00000172936 ENSG00000276561 PMC2993245__F2 Negative regulation of junctional stability in RPE by the PI3K–ROS circuit ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC6681176__F1 Immunometabolism in atherosclerosis ENSG00000162711 ENSG00000111537 ENSG00000125538 PMC6051466__F2 Low antiviral gene expressions at the time of antiretroviral therapy (ART) initiation in cryptococcosis-associated immune reconstitution inflammatory syndrome (C-IRIS) group ENSG00000171855 ENSG00000152778 ENSG00000187608 ENSG00000089127 ENSG00000137965 ENSG00000157601 ENSG00000135114 ENSG00000185745 ENSG00000115267 ENSG00000111331 ENSG00000276561 PMC9549294__F5 Interleukin-1 receptor associated kinase 1 (IRAK1) is epigenetically activated in luminal epithelial cells in prostate cancer ENSG00000157554 ENSG00000180257 ENSG00000182944 ENSG00000109787 ENSG00000121406 ENSG00000151702 ENSG00000157557 ENSG00000173480 ENSG00000077150 ENSG00000183647 ENSG00000198046 ENSG00000197134 ENSG00000244405 ENSG00000083817 ENSG00000136997 ENSG00000175832 ENSG00000142065 ENSG00000184012 ENSG00000088876 ENSG00000185591 ENSG00000182141 ENSG00000176293 ENSG00000130803 ENSG00000178187 ENSG00000177932 ENSG00000084110 ENSG00000107175 ENSG00000143578 ENSG00000071564 ENSG00000115415 ENSG00000177606 ENSG00000010030 ENSG00000196092 ENSG00000128602 PMC9282724__F3 Models of autophagy dysfunction in neurodegenerative diseases ENSG00000112367 ENSG00000123240 ENSG00000030582 ENSG00000158828 ENSG00000069329 ENSG00000165280 ENSG00000073921 ENSG00000105223 ENSG00000147894 ENSG00000184381 ENSG00000108582 ENSG00000183735 ENSG00000188021 ENSG00000198087 PMC4069269__F1 IL-18 signaling ENSG00000162711 ENSG00000285109 ENSG00000172936 ENSG00000185187 ENSG00000125347 ENSG00000175104 ENSG00000137496 PMC6198264__F3 Pathway of biosynthesis and metabolism of testosterone, primary estrogens and progesterone during pregnancy ENSG00000108786 ENSG00000160870 ENSG00000140465 ENSG00000203857 PMC8024309__F8 LncRNA MALAT1 promotes gastric cancer progression via inhibiting autophagic flux and inducing fibroblast activation ENSG00000066044 ENSG00000198793 ENSG00000284099 ENSG00000145321 PMC8549280__F1 SREBP (Sterol Regulatory Element-Binding Protein) pathway: a regulatory bridge between carotenogenesis and sterol biosynthesis in the carotenogenic yeast Xanthophyllomyces dendrorhous ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC11674137__F1 DOX-induced cardiotoxicity in cardiomyocytes ENSG00000239732 ENSG00000189403 ENSG00000168610 PMC11767473__F1 Importance of mesenchymal stem cells (MSC) in the bone-formation mechanism ENSG00000178860 ENSG00000136011 ENSG00000128272 ENSG00000159216 ENSG00000150907 ENSG00000169884 ENSG00000096717 ENSG00000105996 PMC7977035__F1 Postlanosterol cholesterol biosynthesis pathway ENSG00000116133 ENSG00000172893 ENSG00000109929 PMC5889750__F5 Platyfish significantly down modulate the IGF signaling pathway leading to a suppression of cell proliferation, cell growth and cell survival in skin following FL exposure ENSG00000069869 ENSG00000002330 ENSG00000106070 ENSG00000168610 ENSG00000089159 PMC3047613__F2 Model: The kinase IKK may activate Htt degradation by a mammalian version of the yeast Cvt pathway ENSG00000197386 ENSG00000096717 PMC11674137__F2 Landscape of the mitophagy mechanisms ENSG00000090432 ENSG00000177169 ENSG00000183735 ENSG00000123240 ENSG00000198742 ENSG00000158828 ENSG00000069509 PMC5889750__F9 Platyfish skin (A) significantly down modulates the PPARA/RXRA signaling pathway in response to FL; however, both medaka (B) and zebrafish (C) significantly up-modulate the PPARA/RXRA pathway in skin following FL exposure ENSG00000177606 ENSG00000131910 ENSG00000175104 PMC5889750__F8 The telomerase signaling pathway is oppositely modulated in platyfish (A) compared to medaka (B) and zebrafish (C) following FL exposure ENSG00000169291 ENSG00000164362 PMC5889750__F7 In zebrafish following FL exposure, the most significantly modulated pathway in skin is the oncostatin M pathway ENSG00000099985 ENSG00000125148 ENSG00000149968 PMC5889750__F6 Acute phase signaling pathway in fish ENSG00000113905 ENSG00000102871 ENSG00000198793 ENSG00000166278 ENSG00000130159 ENSG00000137055 PMC5397662__F2 A simplified diagram showing the major steps in short-patch base excision repair pathway PMC9575659__F9 Comparative physiological, transcriptomic, and WGCNA analyses reveal the key genes and regulatory pathways associated with drought tolerance in Tartary buckwheat ENSG00000102878 PMC3439829__F4 Diverse cohesinopathy phenotypes ENSG00000171320 ENSG00000147099 ENSG00000164190 ENSG00000129933 ENSG00000083642 ENSG00000141446 PMC4724579__F2 Toll-like receptor 2’s signalling pathways contributing to hepatocarcinoma ENSG00000189403 PMC4724579__F5 Toll-like receptor 9’s signalling pathways influencing hepatocarcinoma ENSG00000239732 ENSG00000189403 PMC8366499__F1 Genetic and Physiological Effects of Insulin on Human Urate Homeostasis ENSG00000169291 ENSG00000118777 PMC4724579__F4 Toll-like receptor 4’s signalling pathways influencing hepatocarcinogenesis ENSG00000189403 ENSG00000136869 PMC3121779__F15 Protective effects of OxPLs against acute lung injury and endothelial barrier dysfunction ENSG00000070831 ENSG00000170458 ENSG00000163914 ENSG00000168036 PMC6856358__F8 Proposed signaling pathway of this study ENSG00000198793 ENSG00000136997 ENSG00000146648 ENSG00000292195 PMC5415275__F9 The putative role of central insulin resistance in attenuating leptin modulation of rHypoE-19 hypothalamic neurons ENSG00000150907 ENSG00000168610 PMC2937585__F1 Folate metabolic pathway ENSG00000228716 PMC7720011__F3 Possible relation of prostate cancer to viral pathogenesis ENSG00000143799 ENSG00000157554 ENSG00000169554 ENSG00000130234 ENSG00000166145 ENSG00000137193 PMC10179893__F5 PS inhibits macrophage M2 polarization via IL-4/STAT6 signaling pathway, and in turn suppresses TAM-induced tumor progression ENSG00000118520 PMC7720011__F1 Functional pathway of androgens and its receptor ENSG00000157554 ENSG00000105329 ENSG00000184012 PMC4394497__F11 Findings from our laboratory using an animal model of the autoimmune disease, RA, reveal disease-related changes in B2-AR signaling that are dependent upon the lymphoid tissue examined PMC10534981__F1 Biomedical engineering approaches for the delivery of JAGGED1 as a potential tissue regenerative therapy ENSG00000186603 ENSG00000114315 PMC5851248__F5 Summary of excitotoxic pathways, mediators and potential therapeutics ENSG00000110218 PMC3884689__F7 Modulators of the microRNA biogenesis pathway via arrayed lentiviral enabled RNAi screening for drug and biomarker discovery ENSG00000137275 ENSG00000143878 ENSG00000088305 ENSG00000100697 ENSG00000160710 ENSG00000171863 ENSG00000105953 ENSG00000162772 ENSG00000096063 ENSG00000012048 ENSG00000170365 ENSG00000128272 ENSG00000159216 ENSG00000244687 ENSG00000126803 ENSG00000130147 ENSG00000130402 ENSG00000077312 ENSG00000099795 ENSG00000120868 ENSG00000113360 PMC6659691__F3 Interferon-gamma (IFNG) pathway and its modeled representation to demonstrate the step-by-step calculations for protein-protein interactions at each node in this pathway and as an annexure section of other pathways ENSG00000033327 ENSG00000135218 ENSG00000163739 ENSG00000169047 ENSG00000118971 ENSG00000168811 ENSG00000112715 ENSG00000121966 ENSG00000138755 ENSG00000136997 ENSG00000102104 ENSG00000026103 ENSG00000104365 ENSG00000081041 ENSG00000159128 ENSG00000151657 ENSG00000109320 ENSG00000027697 ENSG00000213341 ENSG00000277943 ENSG00000108691 ENSG00000111537 ENSG00000115415 ENSG00000102245 ENSG00000010810 ENSG00000164136 ENSG00000112115 PMC6659691__F2 A modeled signaling pathway using a G Protein Coupled Receptor activation as an example ENSG00000171540 ENSG00000087460 PMC12137166__F1 CA PD-OTC of CZ019 displays enhanced glycolysis and noncanonical Krebs cycle metabolism ENSG00000125166 ENSG00000065833 ENSG00000077279 ENSG00000036473 ENSG00000115419 PMC5312414__F1 Triple negative breast cancer: shedding light onto the role of pi3k/akt/mtor pathway ENSG00000198793 PMC2556249__F2 Insulin receptor signaling ENSG00000124102 ENSG00000169047 PMC6659691__F1 Computational Models Accurately Predict Multi-Cell Biomarker Profiles in Inflammation and Cancer ENSG00000169245 ENSG00000150782 ENSG00000159128 ENSG00000111537 ENSG00000102245 ENSG00000164400 ENSG00000113520 ENSG00000136869 ENSG00000112715 ENSG00000115009 PMC5478692__F1 Schematic overview of Imd pathway in Drosophila melanogaster ENSG00000083799 ENSG00000168040 PMC8221540__F8 Immunometabolic Endothelial Phenotypes ENSG00000180210 ENSG00000150907 PMC3928701__F1 Normal signaling pathways and alterations in aged DCs in response to lipopolysaccharide (LPS)/bacteria (A), and in response to self antigen (DNA) ENSG00000172936 PMC5773512__F6 Schematic to illustrate calcimimetic R-467 reversed Cd-induced signaling pathways, followed reinstated intracellular Ca2+ level and ROS generation, restored autophagic flux, alleviated cell apoptosis and stimulated cell proliferation ENSG00000214285 ENSG00000036828 PMC5609950__F9 Identification of LEFTY as a molecular marker for ovarian clear cell carcinoma ENSG00000243709 ENSG00000171791 PMC5354695__F1 Long noncoding RNAs in head and neck cancer ENSG00000088305 ENSG00000165409 ENSG00000105810 ENSG00000112715 PMC9433211__F2 Ferroptosis and Its Relationships with Other Types of Programmed Cell Death: Insights for Potential Therapeutic Benefits in Traumatic Brain Injury ENSG00000090402 ENSG00000083799 PMC10526262__F2 Importance of M1-and M2-Polarized Macrophages in Glioma and as Potential Treatment Targets ENSG00000133048 ENSG00000108679 ENSG00000198793 ENSG00000165819 PMC3377006__F1 Enhanced 15-lipoxygenase activity and elevated eicosanoid production in kidney tumor microenvironment contribute to the inflammation and immune suppression ENSG00000049768 PMC10243706__F1 Necrotizing enterocolitis in premature infants—A defect in the brakes? Evidence from clinical and animal studies ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000185187 ENSG00000168610 ENSG00000184216 PMC8535782__F1 Control of ovarian follicle development by TGFB family signaling ENSG00000157404 ENSG00000164404 ENSG00000130385 ENSG00000180875 PMC4945497__F1 Epigenome-wide DNA Methylation Analysis Implicates Neuronal and Inflammatory Signaling Pathways in Adult Murine Hepatic Tumorigenesis following Perinatal Exposure to Bisphenol A ENSG00000213928 ENSG00000198793 PMC11622655__F1 Effect of Triolein on brain damage after ischemic stroke ENSG00000198793 PMC4945497__F2 Epigenome-wide DNA Methylation Analysis Implicates Neuronal and Inflammatory Signaling Pathways in Adult Murine Hepatic Tumorigenesis following Perinatal Exposure to Bisphenol A ENSG00000087095 ENSG00000172680 ENSG00000170458 ENSG00000138798 ENSG00000175104 ENSG00000127191 ENSG00000111816 ENSG00000146648 ENSG00000026103 PMC9453879__F7 Bailing capsule (Cordyceps sinensis) ameliorates renal triglyceride accumulation through the PPARA pathway in diabetic rats ENSG00000183760 ENSG00000150991 ENSG00000173599 ENSG00000100979 PMC6986448__F3 KISS1 in breast cancer progression and autophagy ENSG00000087245 ENSG00000147437 ENSG00000149968 ENSG00000109320 ENSG00000157227 ENSG00000137203 ENSG00000173039 ENSG00000185591 ENSG00000100985 ENSG00000177548 PMC6176931__F3 Multiple phases and regulation of cilium assembly ENSG00000166579 ENSG00000167461 ENSG00000007047 ENSG00000148384 ENSG00000100379 PMC10873884__F3 Different self-incompatibility systems ENSG00000050748 ENSG00000047936 ENSG00000197121 PMC6804657__F1 Autophagy induced via cGAS-STING and its signaling pathway ENSG00000164430 ENSG00000176986 ENSG00000157954 PMC7915848__F4A Increased Tenascin C, Osteopontin and HSP90 Levels in Plasmatic Small Extracellular Vesicles of Pediatric ALK-Positive Anaplastic Large Cell Lymphoma: New Prognostic Biomarkers? ENSG00000291355 ENSG00000142192 ENSG00000113600 ENSG00000123843 ENSG00000149294 ENSG00000150093 ENSG00000117411 ENSG00000112715 ENSG00000163661 ENSG00000132693 ENSG00000168610 ENSG00000288411 ENSG00000041982 ENSG00000134419 ENSG00000118785 ENSG00000038427 ENSG00000177606 ENSG00000118257 ENSG00000146648 ENSG00000089597 ENSG00000123610 PMC9657932__F6 Enhancing an Oxidative “Trojan Horse” Action of Vitamin C with Arsenic Trioxide for Effective Suppression of KRAS-Mutant Cancers: A Promising Path at the Bedside ENSG00000182511 PMC11354614__F2 Glucose and stress metabolism ENSG00000104812 ENSG00000109511 ENSG00000168748 ENSG00000197043 ENSG00000108515 ENSG00000177238 ENSG00000144712 ENSG00000112992 ENSG00000164879 ENSG00000074800 ENSG00000178538 ENSG00000185015 ENSG00000068976 ENSG00000143412 ENSG00000063180 ENSG00000164708 ENSG00000074410 ENSG00000126432 ENSG00000152556 ENSG00000167434 PMC10531451__F6 Heatmap of DEPs participated in the mevalonate (MEV) and methylerythritol phosphate (MEP) pathways of terpenoid biosynthesis ENSG00000197429 ENSG00000167508 PMC6442683__F4 Dendritic structural plasticity and neuropsychiatric disease ENSG00000038382 ENSG00000198793 ENSG00000284161 ENSG00000167658 PMC1440856__F1 Omega-6 and -3 fatty acids & Prostate Cancer ENSG00000161905 ENSG00000166278 ENSG00000179593 PMC6442683__F3 Dendritic structural plasticity and neuropsychiatric disease ENSG00000038382 ENSG00000147044 ENSG00000160145 ENSG00000197283 ENSG00000166862 ENSG00000167371 ENSG00000132535 ENSG00000179915 ENSG00000292254 ENSG00000182389 ENSG00000196712 PMC8799442__F1 Purinergic signaling elements are correlated with coagulation players in peripheral blood and leukocyte samples from COVID-19 patients ENSG00000196839 ENSG00000087842 ENSG00000110218 PMC9271571__F1 NFKB Inducing Kinase Regulates Intestinal Immunity and Homeostasis ENSG00000104856 ENSG00000173039 ENSG00000162924 ENSG00000166278 ENSG00000131323 ENSG00000127191 PMC8295173__F1 T cell metabolism drives T cell fate and function in to eliminate tumors ENSG00000134982 ENSG00000163599 ENSG00000118520 PMC7653700__F3 T cell senescence-related signaling pathways ENSG00000149311 ENSG00000291603 ENSG00000164430 ENSG00000285109 ENSG00000115415 ENSG00000198793 ENSG00000164362 ENSG00000168610 PMC4646736__F2 Proposed pathway of prostaglandin synthesis and interaction with the cyclooxygenase pathways and VEGFA ENSG00000112715 PMC8042281__F1 Pre-existing chromatin features and damage-induced histone modifications regulate the DNA repair pathways ENSG00000188486 ENSG00000115548 ENSG00000151376 ENSG00000133247 ENSG00000110066 ENSG00000173120 ENSG00000066135 ENSG00000132510 ENSG00000126012 ENSG00000065833 ENSG00000127663 ENSG00000073614 ENSG00000186280 ENSG00000082212 PMC8042281__F3 Histone modifications, dynamically added or removed around the DNA damage site, constitute an integrated signal for the DSBs repair pathway choice ENSG00000188486 ENSG00000185513 ENSG00000151376 ENSG00000133247 ENSG00000083093 ENSG00000110066 ENSG00000173120 ENSG00000011258 ENSG00000196591 ENSG00000066135 ENSG00000165280 ENSG00000112130 ENSG00000012048 ENSG00000198901 ENSG00000065833 ENSG00000163961 ENSG00000051180 ENSG00000082212 PMC4131284__F6 CHK2 kinase promotes pre-mRNA splicing via phosphorylating CDK11p110 ENSG00000149311 ENSG00000012048 ENSG00000140464 PMC5485420__F10 Graphical representation for Mel regulation in DRG neurons ENSG00000065833 ENSG00000148408 ENSG00000125538 ENSG00000069667 PMC5336175__F10 Differential phosphorylation of YBX1 on Ser-176 and Ser-165 and their role in NFKB activation ENSG00000065978 ENSG00000141086 ENSG00000125538 PMC8540409__F6A Metabolomics Investigation of the Metabolic Changes of Raji B Lymphoma Cells Undergoing Apoptosis Induced by Zinc Ions ENSG00000125772 ENSG00000173599 ENSG00000124181 ENSG00000146648 PMC7072361__F1 Potential role of podocalyxin (PODXL) in mature B-cell non-Hodgkin lymphoma (B-NHL) progression ENSG00000107562 ENSG00000169710 ENSG00000109062 PMC9306053__F3 Mitochondria dysfunction in CD8+ T cells as an important contributing factor for cancer development and a potential target for cancer treatment: a review ENSG00000116688 ENSG00000150907 ENSG00000171109 PMC4540474__F6 HTLV-1 Tax Stimulates Ubiquitin E3 Ligase, Ring Finger Protein 8, to Assemble Lysine 63-Linked Polyubiquitin Chains for TAK1 and IKK Activation ENSG00000157625 ENSG00000112130 PMC4959441__F1 RAS-mediated signal transduction pathways and post-translational modification of RAS ENSG00000100473 ENSG00000006451 ENSG00000144118 ENSG00000198793 ENSG00000146648 PMC7396046__F2 Suggested signaling pathway for glucose-induced increase in glucagon synthesis, glucagon secretion, and alpha cell proliferation ENSG00000291971 ENSG00000198793 ENSG00000146648 PMC9657932__F2 Enhancing an Oxidative “Trojan Horse” Action of Vitamin C with Arsenic Trioxide for Effective Suppression of KRAS-Mutant Cancers: A Promising Path at the Bedside ENSG00000146648 PMC8197596__F1 Severe COVID-19 in Alzheimer’s disease: APOE4’s fault again? ENSG00000163818 ENSG00000148400 ENSG00000157227 ENSG00000130234 ENSG00000173039 ENSG00000168036 ENSG00000096717 PMC7504526__F4 mtDNA-triggered cGAS-YAP pathway ENSG00000183735 ENSG00000164430 ENSG00000131023 PMC6910929__F3 Regulation of PI3K/AKT signaling pathways ENSG00000002330 PMC12012199__F7 Targeted demethylation of EphA7 inhibits tumorigenesis via the SP1/DNMT1 & PI3K/AKT axis and improves the response to multiple therapies in cervical cancer ENSG00000135333 ENSG00000185591 ENSG00000184349 PMC7313447__F7 Astragaloside IV attenuates high glucose-induced EMT by inhibiting the TGFB/Smad pathway in renal proximal tubular epithelial cells ENSG00000170558 PMC5265847__F3 TP53-centered protein–protein interaction network identified based on the Level 2 gene set using Ingenuity Pathway Analysis ENSG00000163564 ENSG00000134460 ENSG00000143514 ENSG00000099985 ENSG00000074181 ENSG00000086991 ENSG00000276644 ENSG00000124766 ENSG00000049249 ENSG00000164695 ENSG00000127074 PMC7419982__F5 Sodium (Na+) and potassium (K+) ion homeostasis by SOS pathway ENSG00000115904 ENSG00000100485 PMC6627931__F1 Role of Leukotriene B4 Receptor-2 in Mast Cells in Allergic Airway Inflammation ENSG00000137033 ENSG00000172936 ENSG00000136869 PMC4700430__F2 Blood-based gene expression signatures of medication-free outpatients with major depressive disorder: integrative genome-wide and candidate gene analyses ENSG00000291368 PMC4037924__F1 Ancestral Ca2+ Signaling Machinery in Early Animal and Fungal Evolution ENSG00000101871 ENSG00000168924 ENSG00000204520 PMC7699248__F2 Wnt/Beta-catenin signaling pathway represses VDR expression ENSG00000168036 PMC7699248__F1 Mechanisms by which 1,25(OH)2D3 interferes the Wnt/Beta-catenin signaling pathway in human CRC cells ENSG00000125538 ENSG00000168036 ENSG00000196628 PMC6857441__F7 Schematic overview of the pathways linking glucocorticoids and their precursors to their urine metabolites ENSG00000176387 PMC2681001__F1 Biosynthetic Pathway of Coenzyme Q10 ENSG00000132423 ENSG00000115520 ENSG00000119723 ENSG00000162377 ENSG00000088682 ENSG00000183513 ENSG00000148459 ENSG00000173085 ENSG00000135469 PMC6857441__F3 Schematic overview of androgen biosynthesis ENSG00000086696 ENSG00000151632 ENSG00000161513 ENSG00000203859 ENSG00000127948 ENSG00000176387 PMC8273916__F8 Kaempferol Alleviates Steatosis and Inflammation During Early Non-Alcoholic Steatohepatitis Associated With Liver X Receptor Alpha-Lysophosphatidylcholine Acyltransferase 3 Signaling Pathway ENSG00000128272 PMC7552065__F2 HBV infection pathway ENSG00000107338 PMC4335176__F2 Pathways leading to stimulation of extracellular-regulated kinase (ERK) and AKT phosphorylation by fluoxetine in astrocytes ENSG00000113070 ENSG00000138798 ENSG00000146648 PMC7397420__F12 Demonstration of the putative mechanism of action of lithium in the NFKB signalling pathway ENSG00000166167 ENSG00000162433 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC3570922__F1 PI3K/AKT/GSK3/mTOR signaling ENSG00000198793 ENSG00000168036 PMC8745344__F8A Multi-Omics Approach Profiling Metabolic Remodeling in Early Systolic Dysfunction and in Overt Systolic Heart Failure ENSG00000130304 ENSG00000157184 ENSG00000069482 ENSG00000118729 ENSG00000198626 ENSG00000168924 ENSG00000142082 ENSG00000161714 PMC8876702__F2 Reservoir of Persistent Human Papillomavirus Infection; Strategies for Elimination Using Anti-Viral Therapies ENSG00000187957 ENSG00000168214 ENSG00000198793 ENSG00000103335 PMC7916890__F3 Crosstalk between mTOR signaling and PI3K/Akt pathway ENSG00000106070 ENSG00000169047 PMC7916890__F2 Amino acids and growth factors-mediated activation of the mTORC1 signaling ENSG00000114388 ENSG00000177058 ENSG00000198198 ENSG00000127580 ENSG00000164654 ENSG00000103091 PMC8283590__F2 Molecular pathways in viral hepatitis-associated liver carcinogenesis: An update ENSG00000081041 ENSG00000291971 PMC8283590__F1 Molecular pathways in viral hepatitis-associated liver carcinogenesis: An update ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC2192627__F1 Signaling mechanisms involved in lifespan regulation and the cellular response to genotoxic stress ENSG00000149311 ENSG00000169047 ENSG00000198793 ENSG00000096717 ENSG00000140443 PMC8283590__F3 Molecular pathways in viral hepatitis-associated liver carcinogenesis: An update ENSG00000166167 ENSG00000126016 ENSG00000186575 ENSG00000168036 ENSG00000150457 ENSG00000131023 ENSG00000196628 PMC10941343__F9 Elucidating the anti-hypertensive mechanisms of Uncaria rhynchophylla-Alisma plantago-aquatica L: an integrated network pharmacology, cluster analysis, and molecular docking approach ENSG00000142192 ENSG00000169291 ENSG00000173786 ENSG00000127528 PMC8432043__F1 Exploring the pathways to chronic lymphocytic leukemia ENSG00000108702 ENSG00000107562 ENSG00000117425 ENSG00000137077 ENSG00000026508 ENSG00000185483 ENSG00000126353 ENSG00000162692 ENSG00000128602 ENSG00000277943 ENSG00000121966 PMC8269276__F1 Promising Treatment Options for Axial Spondyloarthritis: An Overview of Experimental Pharmacological Agents ENSG00000111537 ENSG00000105639 PMC4591212__F1 Altered modulation of the IL-8 signaling pathway in AH livers with MDBs ENSG00000127955 ENSG00000186469 ENSG00000182541 PMC11997178__F5 TRAF2 roles in cancer ENSG00000163251 ENSG00000198793 ENSG00000185483 ENSG00000112186 ENSG00000127191 PMC7478739__F6 SOAT1 abrogates cholesterol feedback inhibition to promote mevalonate pathway dependency in PDAC ENSG00000057252 ENSG00000130164 ENSG00000163914 ENSG00000113161 PMC11997178__F2 TRAF2 role in the TNFR1 and TNFR2 signaling pathways ENSG00000137275 ENSG00000115415 ENSG00000102871 ENSG00000157625 ENSG00000168040 ENSG00000102010 ENSG00000127191 ENSG00000285379 PMC11997178__F3 TRAF2 role in the canonical and noncanonical Wnt signaling pathways ENSG00000185483 ENSG00000168036 ENSG00000154310 ENSG00000127191 ENSG00000196628 PMC5013308__F5 Pathway map of quantitative comparisons of metabolic proteins in RKO cell lines ENSG00000131473 ENSG00000125166 ENSG00000197713 ENSG00000160883 ENSG00000090402 ENSG00000117118 ENSG00000169710 ENSG00000023697 ENSG00000172340 ENSG00000146733 ENSG00000284320 ENSG00000128050 ENSG00000074800 ENSG00000100412 ENSG00000136872 ENSG00000091140 ENSG00000152556 ENSG00000062485 PMC5013308__F4 Pathway map of quantitative comparisons of metabolic proteins in DLD-1 cell lines ENSG00000131473 ENSG00000125166 ENSG00000197713 ENSG00000160883 ENSG00000117118 ENSG00000169710 ENSG00000135069 ENSG00000023697 ENSG00000172340 ENSG00000146733 ENSG00000284320 ENSG00000128050 ENSG00000074800 ENSG00000092621 ENSG00000100412 ENSG00000136872 ENSG00000146701 ENSG00000091140 ENSG00000115419 ENSG00000159399 ENSG00000152556 ENSG00000062485 PMC2865574__F3 Wnt signaling is a complex pathway, believed to be involved in the regulation of divergent processes, including the maintenance of pluripotency and commitment to differentiation ENSG00000196154 ENSG00000168036 ENSG00000168646 PMC9604538__F2 Pathways for ATG16L1-mediated conjugation of LC3 to membranes during autophagy and LAP/CASM conjugation via the V-ATPase-ATG16L1 axis ENSG00000198382 ENSG00000126775 ENSG00000144848 ENSG00000157954 ENSG00000145782 ENSG00000057663 PMC11186359__F8 Schematic diagram showing how PM increases AREG-dependent glutamine metabolism and lung cancer proliferation ENSG00000109321 ENSG00000198793 ENSG00000146648 PMC5716183__F1 One-carbon metabolism, transmethylation reactions and DNA demethylation ENSG00000099860 ENSG00000116984 PMC3175556__F7 Schematic diagrams of the signal transduction in TCDD-induced MUC5AC gene expression and the conventional AhR pathway in the activation of CYP1A1 expression ENSG00000185591 ENSG00000146648 ENSG00000106546 PMC5215528__F1 ARE gene product interactome ENSG00000023445 ENSG00000087245 ENSG00000107562 ENSG00000081041 ENSG00000105329 ENSG00000138798 ENSG00000164399 ENSG00000171791 ENSG00000112715 ENSG00000102678 ENSG00000073756 ENSG00000007171 ENSG00000108691 ENSG00000177606 ENSG00000136997 ENSG00000125538 ENSG00000163734 ENSG00000184371 ENSG00000164400 ENSG00000169429 ENSG00000123374 ENSG00000100985 ENSG00000162692 PMC8001969__F4 MTOR signaling pathway and its important regulatory functions are shown ENSG00000101407 ENSG00000177169 ENSG00000169047 ENSG00000118515 ENSG00000155792 ENSG00000112561 PMC9214030__F2 From a Hetero- to a Methylotrophic Lifestyle: Flash Back on the Engineering Strategies to Create Synthetic Methanol-User Strains ENSG00000197713 ENSG00000226275 ENSG00000136371 ENSG00000084110 ENSG00000167701 PMC7521558__F7 Schematic model summarizing the effects and signaling pathway of SRA in RCC ENSG00000135446 ENSG00000170558 ENSG00000272398 ENSG00000026508 ENSG00000105810 ENSG00000118777 PMC2793058__F10 IFNG signaling pathway in retinal pigment epithelium ENSG00000115415 ENSG00000001626 PMC7747940__F2 Porphyromonas gingivalis: Immune subversion activities and role in periodontal dysbiosis ENSG00000174125 ENSG00000172936 ENSG00000150455 ENSG00000121966 PMC8927572__F3 Proposed precision treatment strategies for MAPK pathway-mutated head and neck cancer ENSG00000157764 ENSG00000065361 ENSG00000146648 PMC8927572__F2 Components of the MAPK pathway are mutated in both HNSCC (at somatic level) and in various RASopathies at germline level ENSG00000108861 ENSG00000138166 ENSG00000166068 ENSG00000196712 ENSG00000164086 PMC5861627__F3 Crosstalk between Shh pathway and others ENSG00000157404 ENSG00000281324 ENSG00000002330 ENSG00000157764 ENSG00000162337 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000121879 ENSG00000125879 ENSG00000166813 ENSG00000164690 ENSG00000128602 ENSG00000146648 PMC5861627__F1 Canonical activation of Shh pathway in vertebrates ENSG00000157404 ENSG00000128602 PMC8262573__F1 Translational Control is an Emerging Mechanism of Programmed Cell Death Ligand 1 (PD-L1)/Programmed Cell Death Protein 1 (PD-1) Regulation in Cancer ENSG00000111537 ENSG00000144895 ENSG00000115415 ENSG00000136997 PMC8761741__F2 Criminal of Adverse Pregnant Outcomes: A Perspective From Thyroid Hormone Disturbance Caused by SARS-CoV-2 ENSG00000042832 ENSG00000125538 ENSG00000170893 PMC6771534__F2 Evasion of the IFN‐I signaling pathway by HSV1 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000164342 PMC9367940__F9 Taste Receptor Activation in Tracheal Brush Cells by Denatonium Modulates ENaC Channels via Ca2+, cAMP and ACh ENSG00000070985 ENSG00000001626 PMC2761115__F2 Gonad function and sexual differentiation ENSG00000162552 ENSG00000169218 ENSG00000104899 ENSG00000143355 ENSG00000170370 ENSG00000125398 ENSG00000168066 ENSG00000163083 ENSG00000134363 ENSG00000139549 ENSG00000102678 PMC11662631__F8 Schematic show that the mechanism of hsa_circ_100791 promote the progression of allergic rhinitis ENSG00000137033 ENSG00000135387 ENSG00000204977 ENSG00000113520 PMC4016907__F5 Both images were created using IPA ENSG00000162889 ENSG00000104365 ENSG00000152495 ENSG00000178999 ENSG00000108443 ENSG00000213341 ENSG00000183765 ENSG00000117020 ENSG00000117650 ENSG00000166501 ENSG00000118515 ENSG00000105723 ENSG00000253729 PMC12000036__F2 Functions of TREM2 ENSG00000115415 ENSG00000291971 ENSG00000146094 ENSG00000198793 ENSG00000115904 ENSG00000168036 ENSG00000172936 ENSG00000075239 PMC4874901__F8 JNK mediates mouse liver injury through a novel Sab (SH3BP5) dependent pathway leading to inactivation of intramitochondrial Src ENSG00000291971 ENSG00000125170 PMC8614257__F8 Equine Endometrosis Pathological Features: Are They Dependent on NFKB Signaling Pathway? ENSG00000170961 ENSG00000173039 PMC12000036__F1 TREM2 signaling pathway ENSG00000291971 ENSG00000146094 ENSG00000198793 ENSG00000197943 ENSG00000137845 PMC1420312__F5 Impact of SV40 ST on the Notch, Wnt, and Hedgehog Pathways ENSG00000138795 ENSG00000154764 ENSG00000137673 ENSG00000196975 ENSG00000090863 ENSG00000134982 ENSG00000089127 ENSG00000197471 ENSG00000138829 ENSG00000261236 ENSG00000168036 ENSG00000135069 ENSG00000106829 ENSG00000156298 ENSG00000004455 ENSG00000149968 ENSG00000026508 ENSG00000111186 ENSG00000285438 ENSG00000164690 ENSG00000154188 ENSG00000128602 ENSG00000155760 PMC7492727__F4 Proposed pathological mechanisms of MuSK autoantibodies at the NMJ ENSG00000030304 ENSG00000087085 ENSG00000291368 PMC8092973__F1 Simplified schematics of the mechanisms of replication fork restart upon replication stress ENSG00000143799 ENSG00000083093 ENSG00000188827 ENSG00000147231 ENSG00000121988 ENSG00000077514 ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000099381 ENSG00000166508 ENSG00000093009 ENSG00000012048 ENSG00000144554 ENSG00000125319 ENSG00000108384 ENSG00000051180 ENSG00000138375 ENSG00000124535 ENSG00000101751 ENSG00000164306 ENSG00000130997 ENSG00000187741 ENSG00000139618 ENSG00000132646 ENSG00000111642 ENSG00000122008 PMC8840702__F1 Ferroptosis in cancer therapy: a novel approach to reversing drug resistance ENSG00000148346 ENSG00000167468 ENSG00000112984 ENSG00000111684 ENSG00000165527 ENSG00000162772 ENSG00000127948 PMC4488672__F5 Hierarchical signaling pathway expression regulates regeneration ENSG00000154342 ENSG00000138795 ENSG00000168036 ENSG00000164690 ENSG00000163501 PMC10950698__F9 IL-13 facilitates ferroptotic death in asthmatic epithelial cells via SOCS1-mediated ubiquitinated degradation of SLC7A11 ENSG00000168003 ENSG00000151012 ENSG00000131724 PMC9605170__F4 Incorporation of Suppression of Tumorigenicity 2 into Random Survival Forests for Enhancing Prediction of Short-Term Prognosis in Community-ACQUIRED Pneumonia ENSG00000137033 ENSG00000172936 ENSG00000184216 ENSG00000076604 PMC7920043__F1 Schema of “signaling” pathways for CS effects ENSG00000146648 PMC4521272__F1 Polymorphism Near the Interleukin-28B Gene and Anti-Hepatitis C Viral Response ENSG00000236637 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC9604538__F5 Interactions between pathogens and LAP/CASM ENSG00000145782 ENSG00000118640 ENSG00000057663 PMC8495264__F7 Thrombospondin-4 Is a Soluble Dermal Inflammatory Signal That Selectively Promotes Fibroblast Migration and Keratinocyte Proliferation for Skin Regeneration and Wound Healing ENSG00000107404 ENSG00000060558 ENSG00000168036 ENSG00000164327 ENSG00000171791 ENSG00000084628 ENSG00000160973 ENSG00000263014 ENSG00000258659 ENSG00000291649 ENSG00000171819 ENSG00000146038 ENSG00000162599 PMC3706794__F8 Proposed mechanism demonstrating the interplay of heme oxygenase 1 (HO-1) and the Wnt canonical pathway in the modulation of adipogenesis in mesenchymal stem cells (MSC)-derived adipocytes ENSG00000178860 ENSG00000135218 ENSG00000169884 ENSG00000168036 PMC6580798__F3 Proposed pathway for metabolic detoxication of AAI ENSG00000181019 ENSG00000140505 ENSG00000140465 ENSG00000132693 PMC8227208__F4 p53/p73 Protein Network in Colorectal Cancer and Other Human Malignancies ENSG00000245848 ENSG00000181019 ENSG00000078747 ENSG00000161970 ENSG00000102921 ENSG00000146648 ENSG00000064300 ENSG00000164609 PMC8623382__F1 Comprehensive Review on the Interplay between Neisseria spp. and Host Sphingolipid Metabolites ENSG00000100422 ENSG00000063176 ENSG00000102172 PMC6689986__F1 Autophagy in the differentiation/function of osteoclast, osteoblast and osteocyte ENSG00000170365 ENSG00000057663 PMC7047114__F6 NFKB-pathway ENSG00000173221 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC8256831__F2 Adult Hippocampal Neurogenesis and Alzheimer's Disease: Novel Application of Mesenchymal Stem Cells and their Role in Hippocampal Neurogenesis ENSG00000178860 PMC8631414__F5 Low-intensity extracorporeal shock wave therapy promotes recovery of sciatic nerve injury and the role of mechanical sensitive YAP/TAZ signaling pathway for nerve regeneration PMC9074275__F6 Tetraspanin 7 promotes osteosarcoma cell invasion and metastasis by inducing EMT and activating the FAK-Src-Ras-ERK1/2 signaling pathway ENSG00000156298 ENSG00000291971 ENSG00000170558 PMC5329892__F3 WNK kinases in development and disease ENSG00000143867 ENSG00000134982 ENSG00000168036 ENSG00000080166 PMC9389066__F2 Pyroptosis and inflammasomes in diabetic wound healing ENSG00000278718 ENSG00000162711 ENSG00000147697 PMC12073904__F7 Mechanistic model of inflammation, mitochondrial dysfunction, and neuromuscular junction characteristics of HF and LF octogenarians ENSG00000142192 ENSG00000129910 ENSG00000105550 ENSG00000154639 ENSG00000181104 ENSG00000148926 ENSG00000167772 ENSG00000277586 ENSG00000188157 ENSG00000173614 ENSG00000154654 ENSG00000008130 ENSG00000130513 PMC9389066__F1 Pyroptosis and inflammasomes in diabetic wound healing ENSG00000162711 ENSG00000163568 ENSG00000091592 PMC3622708__F8 Wnt3a/Beta-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signaling program ENSG00000148400 ENSG00000151379 ENSG00000179111 ENSG00000106003 PMC3871231__F2 New and emerging HDAC inhibitors for cancer treatment ENSG00000094631 ENSG00000171720 ENSG00000101849 ENSG00000147099 ENSG00000196591 ENSG00000150459 ENSG00000100429 ENSG00000288325 ENSG00000177565 ENSG00000164105 PMC8401922__F3 AMPK and Its Downstream Signals in Pain Regulation ENSG00000182578 ENSG00000177169 ENSG00000184371 ENSG00000167965 PMC11352841__F2 Bioactive compounds targeting NFKB signaling pathway to prevent inflammatory changes and mastitis ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC11352841__F1 Bacterial induced mastitis via activating TLR2/TLR4/NFKB signaling pathways in mammary gland cells ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC3965010__F1 Example of disease curation and visualization in Reactome ENSG00000160190 ENSG00000278373 ENSG00000079432 ENSG00000105205 ENSG00000281500 PMC7339281__F2 METTL3 regulates cell proliferation ENSG00000138795 ENSG00000156802 ENSG00000136997 ENSG00000168036 ENSG00000146648 ENSG00000072364 ENSG00000128191 ENSG00000165819 PMC6316632__F1 Simple central carbon network of the Xanthomonas oryzae pv. oryzae BXO43 strain ENSG00000122966 ENSG00000166863 ENSG00000172005 PMC7396579__F3 Glucocorticoid resistance (GCR) in sepsis ENSG00000145321 ENSG00000124253 ENSG00000157514 PMC11352841__F3 Probiotic targetingTLR2/TLR4 /NFKB signaling pathway to prevent inflammatory changes and mastitis ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC4694690__F1 Clinical use of cobicistat as a pharmacoenhancer of human immunodeficiency virus therapy ENSG00000142494 ENSG00000112499 ENSG00000197375 ENSG00000184207 ENSG00000197208 ENSG00000118777 ENSG00000180638 ENSG00000023839 PMC5436210__F2 Comprehensive analysis of a microRNA expression profile in pediatric medulloblastoma ENSG00000147649 ENSG00000204103 ENSG00000113070 ENSG00000115904 ENSG00000066739 ENSG00000169710 ENSG00000131910 ENSG00000099194 ENSG00000109819 ENSG00000159216 ENSG00000130222 ENSG00000055609 ENSG00000113263 ENSG00000096717 ENSG00000185129 ENSG00000198286 ENSG00000171885 ENSG00000138385 PMC7339281__F3 METTL3 regulates cell apoptosis ENSG00000141579 ENSG00000102466 ENSG00000112561 ENSG00000164690 ENSG00000138668 ENSG00000165819 PMC9231174__F3 Calcifediol for Use in Treatment of Respiratory Disease ENSG00000111012 ENSG00000118972 ENSG00000111537 ENSG00000167207 ENSG00000198793 ENSG00000105697 ENSG00000136869 PMC5436210__F3 Comprehensive analysis of a microRNA expression profile in pediatric medulloblastoma ENSG00000160789 ENSG00000100697 ENSG00000099194 ENSG00000119912 ENSG00000184481 ENSG00000081189 ENSG00000123908 PMC4194559__F1 Presents an overview of the Rho/Rho-associated protein kinases signaling pathway ENSG00000070831 ENSG00000163914 ENSG00000067900 PMC2858867__F1 ALPS – Ten Lessons from an International Workshop on a Genetic Disease of Apoptosis ENSG00000168040 ENSG00000064012 PMC11989906__F4 Adipose Tissue Metabolism in Naturally Grazing Sheep at Different Growth Stages: Insights from mRNA and miRNA Profiles ENSG00000067057 ENSG00000288174 ENSG00000110931 ENSG00000169710 ENSG00000099194 PMC7338975__F1 Molecular Mechanisms of Ferroptosis and Its Role in Pulmonary Disease ENSG00000151012 ENSG00000196839 ENSG00000167468 ENSG00000167996 ENSG00000111684 ENSG00000023909 ENSG00000115107 ENSG00000057663 ENSG00000136381 ENSG00000079999 PMC4140250__F1 Schematic view of the sphingolipid metabolism in S ENSG00000228278 ENSG00000229314 PMC5415104__F9 Anti-microbial peptide TP359 attenuates inflammation in human lung cells infected with Pseudomonas aeruginosa via TLR5 and MAPK pathways ENSG00000187554 ENSG00000172936 ENSG00000136869 PMC5415376__F3 Targeted knockdown of polo-like kinase 1 alters metabolic regulation in melanoma ENSG00000067992 ENSG00000164708 ENSG00000124253 ENSG00000146701 ENSG00000105723 ENSG00000159399 ENSG00000062485 PMC7011072__F3 Curated interactions for HES1, NOTCH1, and TNFA genes using SIGNOR database ENSG00000168214 ENSG00000148400 ENSG00000263528 ENSG00000132170 PMC8969013__F1 STING1 in Different Organelles: Location Dictates Function ENSG00000183735 ENSG00000164430 ENSG00000088888 PMC5713689__F3 Signal pathway of the immune inhibitory receptors.Notes: PD-1 crosslinks the TCR and recruits the SHP-2, which can dephosphorylate the ZAP-70 to prevent the SLP-76 and LAT from being phosphorylated ENSG00000089692 ENSG00000291603 ENSG00000213658 ENSG00000181847 ENSG00000198793 ENSG00000049768 ENSG00000175104 PMC7020470__F6 Schematic diagram depicting MetAP2 implication in different pathways ENSG00000002330 ENSG00000070831 ENSG00000111142 PMC7513295__F4 PPI network analysis ENSG00000110944 ENSG00000089127 ENSG00000072274 ENSG00000186818 ENSG00000110057 ENSG00000069667 ENSG00000103811 ENSG00000155307 ENSG00000103490 ENSG00000263528 ENSG00000076641 ENSG00000136869 ENSG00000169508 ENSG00000023445 ENSG00000105369 ENSG00000122122 ENSG00000081237 ENSG00000197471 ENSG00000159905 ENSG00000178386 ENSG00000196378 ENSG00000213341 ENSG00000204920 ENSG00000105639 ENSG00000162594 ENSG00000131019 ENSG00000135077 ENSG00000067066 ENSG00000226275 ENSG00000179344 ENSG00000117091 ENSG00000115415 ENSG00000118503 ENSG00000156127 ENSG00000074966 ENSG00000026751 ENSG00000135605 PMC7056469__F4 Oxidative stress are targets of antioxidant dietary compounds ENSG00000205221 ENSG00000079999 PMC10876307__F5 Suppression of Migration and Invasion by 4-Carbomethoxyl-10-Epigyrosanoldie E from the Cultured Soft Coral Sinularia sandensis through the MAPKs Pathway on Oral Cancer Cells ENSG00000185015 ENSG00000063180 ENSG00000074410 PMC7355474__F8 Graphical representation to elaborate on the possible mechanism underlying antioxidative and anti-inflammatory potential of A3 against the p-MCAO-induced brain injury ENSG00000178573 ENSG00000136869 ENSG00000171791 PMC3974768__F8 Stem and Progenitor Cell Subsets Are Affected by JAK2 Signaling and Can Be Monitored by Flow Cytometry ENSG00000161647 ENSG00000117091 ENSG00000108852 PMC12237660__F3 TREM2/TREM2+macrophages in MASH ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC12237660__F2 Targeting TREM2 signal pathway ENSG00000137845 PMC12237660__F1 MASH (Metabolism and immune response) ENSG00000121807 ENSG00000026103 PMC9006795__F1 Aneurysmal subarachnoid haemorrhage—cerebral vasospasm and prophylactic ibuprofen: a randomised controlled pilot trial protocol ENSG00000163914 ENSG00000166278 ENSG00000174611 PMC5118702__F5 Molecular and biological pathway interaction map analysis of altered proteins from the CCI samples (1 vs ENSG00000074800 ENSG00000136854 PMC6943653__F1 Scheme of the insulin/IGF-1 signaling pathway (IIS) in C ENSG00000118515 PMC4007207__F9 Model of the role of an epidermal barrier defect in tumour protection ENSG00000101146 ENSG00000145777 PMC6030864__F1 Pathway relationship network ENSG00000111837 ENSG00000198793 ENSG00000172005 PMC8234459__F3 Paradoxical Roles of Desmosomal Components in Head and Neck Cancer ENSG00000137673 ENSG00000138798 ENSG00000134757 ENSG00000168036 ENSG00000081277 ENSG00000184363 ENSG00000134760 ENSG00000046604 ENSG00000134755 ENSG00000167754 ENSG00000019549 ENSG00000112851 ENSG00000146648 PMC7878744__F1 Renal metabolism and hypertension ENSG00000115419 ENSG00000062485 PMC3026934__F2 Signaling pathway induced by Dectin-1 ENSG00000187796 ENSG00000291971 PMC7023692__F3 Representative diagram of circRNA mediated ceRNA network and oncogene signaling pathways ENSG00000078747 ENSG00000188064 ENSG00000100697 ENSG00000168036 ENSG00000160410 ENSG00000174963 ENSG00000168610 ENSG00000155760 ENSG00000155363 PMC3140958__F6 Protein interaction maps of the defined ratio clusters, (A) [G1_S]#3 and (B) [G1_S]#2 ENSG00000103365 PMC4981436__F4 The Integration of Epistasis Network and Functional Interactions in a GWAS Implicates RXR Pathway Genes in the Immune Response to Smallpox Vaccine ENSG00000132170 PMC3256462__F1 Basic signaling pathways and relevant targets together with their inhibitors associated with endocrine resistance Estrogen receptor alpha (ER) and the growth factors (esp ENSG00000291971 ENSG00000138798 PMC6369349__F1 Molecular signaling pathway of TNFR2 ENSG00000102871 ENSG00000056558 ENSG00000157625 ENSG00000131323 ENSG00000168040 ENSG00000127191 PMC4713888__F1 Immune evasion mechanisms seen in acute leukemia.Multiple immune pathways and functions are targeted by acute leukemia ENSG00000089692 ENSG00000204520 ENSG00000168610 PMC3499976__F1 Wnt transduction pathways and their functions during synapse development, function and plasticity ENSG00000134982 ENSG00000030304 ENSG00000163914 ENSG00000168036 PMC8678454__F7 Global Profiling of N-Glycoproteins and N-Glycans in the Diatom Phaeodactylum tricornutum ENSG00000182858 PMC8636065__F7 Hippocampal Transcriptome-Wide Association Study Reveals Correlations Between Impaired Glutamatergic Synapse Pathway and Age-Related Hearing Loss in BXD-Recombinant Inbred Mice ENSG00000171189 ENSG00000125675 ENSG00000179603 ENSG00000164082 ENSG00000120251 ENSG00000115419 ENSG00000292254 PMC5814228__F6 Deciphering microRNA targets in pancreatic cancer using miRComb R package ENSG00000163840 ENSG00000273529 ENSG00000133961 ENSG00000114315 ENSG00000110042 PMC6089339__F7 Summary of the location pattern of CFP (blue), YFP (yellow), neuronal (PV) and activity markers (Arc) in the hippocampus ENSG00000164879 ENSG00000173599 ENSG00000198576 ENSG00000145321 PMC5855671__F2 Integrins act as “double agents” during Helicobacter pylori infection in the stomach, serving to potentiate bacterial pathogenicity while also aiding in the immune response ENSG00000146648 ENSG00000065802 PMC11234204__F5 Regulatory factors involved in sensitivity and resistance to ferroptosis in HCC patients treated with sorafenib ENSG00000148346 ENSG00000151012 ENSG00000169710 ENSG00000099194 ENSG00000189376 ENSG00000168610 ENSG00000168003 ENSG00000006194 ENSG00000186575 ENSG00000128272 ENSG00000167468 ENSG00000145354 ENSG00000071626 PMC7672575__F5 Signaling pathways of MD-2/TLR4 axis that lead to stimulating the immune responses ENSG00000183735 ENSG00000125538 ENSG00000172005 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC4701050__F3 Origin and in vitro generation of eCPCs ENSG00000166823 ENSG00000285109 ENSG00000128052 ENSG00000156574 ENSG00000138606 ENSG00000081189 ENSG00000016082 ENSG00000197461 PMC7672575__F7 Potential antiviral mechanisms of action for honey contain caffeic acid, CAPE, galangin, and chrysin against SARS-CoV-2 ENSG00000069482 ENSG00000130234 PMC5882022__F1 The regulatory roles of different sirtuins in the reprogramming of human skin fibroblasts to generate induced pluripotent stem cells ENSG00000187531 ENSG00000124523 ENSG00000128342 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000089163 ENSG00000168610 ENSG00000283100 PMC7716408__F6 Proposed molecular mechanisms for PA regulating ferroptosis in IRI-AKI ENSG00000168003 ENSG00000151012 ENSG00000167468 PMC11234204__F1 Canonical mechanism of ferroptosis ENSG00000168003 ENSG00000135423 ENSG00000161905 ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000111371 ENSG00000102967 ENSG00000115107 ENSG00000123983 PMC11234204__F4 Metabolic dysregulation mediates ferroptosis in HCC ENSG00000168003 ENSG00000115946 ENSG00000151012 ENSG00000167114 ENSG00000172893 ENSG00000167468 ENSG00000099194 ENSG00000105677 ENSG00000105552 PMC3243079__F2 Non-genomic ERA pathway ENSG00000291971 ENSG00000177606 PMC2896911__F8 Regulatory network that links the activities of an ensemble of transcriptional regulators, signaling components and survival factors in developing B cells into a common pathway ENSG00000157554 ENSG00000020633 ENSG00000171791 ENSG00000142082 ENSG00000121966 ENSG00000095585 ENSG00000177455 ENSG00000157557 ENSG00000172216 ENSG00000150907 ENSG00000137265 ENSG00000283060 ENSG00000282899 ENSG00000166349 ENSG00000138795 ENSG00000105369 ENSG00000148400 ENSG00000140968 ENSG00000007312 ENSG00000124766 ENSG00000168610 ENSG00000128218 ENSG00000169575 ENSG00000061273 ENSG00000107485 ENSG00000196092 ENSG00000122592 ENSG00000102974 PMC7766288__F2 Mechanisms of several lncRNAs in CC ENSG00000281406 ENSG00000132646 ENSG00000198793 ENSG00000168036 PMC11234204__F3 NRF2 is involved in preventing lipid peroxidation and ferroptosis in HCC ENSG00000151012 ENSG00000100577 ENSG00000145920 ENSG00000136231 ENSG00000079999 ENSG00000168003 ENSG00000160097 ENSG00000181019 ENSG00000167468 ENSG00000167996 ENSG00000159346 ENSG00000096717 ENSG00000083807 PMC5994595__F3 Excitatory toxicity model of methamphetamine ENSG00000128272 ENSG00000176046 PMC5506270__F1 T cell signaling, activation and antigen recognition ENSG00000134982 PMC7897342__F2 Role of the ATF/CREB family in the pathway involved in hepatic lipid metabolism ENSG00000063176 ENSG00000128272 ENSG00000137504 ENSG00000042832 ENSG00000144895 ENSG00000110244 ENSG00000105550 ENSG00000158874 ENSG00000096717 ENSG00000026103 PMC3711318__F10 Proposed model for activation of the ATR/Chk1 signaling pathway and G2/M phase cell cycle arrest induced by HNE ENSG00000134057 PMC8080578__F4 New paradigm for the regulation of STAT2 protein in melanoma formation ENSG00000105723 ENSG00000109670 PMC3856238__F6 Global Proteomics and Pathway Analysis of Pressure-overload Induced Heart Failure and Its Attenuation by Mitochondrial Targeted Peptides ENSG00000178127 ENSG00000131473 ENSG00000073578 ENSG00000196839 ENSG00000197444 ENSG00000117118 ENSG00000186010 ENSG00000138777 ENSG00000119013 ENSG00000146701 ENSG00000147123 PMC4207979__F1 One-carbon metabolism is required for the synthesis of purines, thymidylate (dTMP), and methionine ENSG00000228716 ENSG00000065911 PMC3515668__F1 Schematic representation of the potential disruption of the hepatic GHR-JAK2-STAT5b signal transduction pathway by TCDD ENSG00000112964 ENSG00000106546 PMC6082850__F8 Antidepressant and anxiolytic mechanism of acupuncture in a PTSD rat model ENSG00000198793 ENSG00000008056 PMC7860207__F2 Significantly enriched Cell Cycle pathway from genes with high DE prior probabilities ENSG00000118007 ENSG00000105329 ENSG00000205250 ENSG00000073111 ENSG00000277273 ENSG00000091651 ENSG00000145386 ENSG00000166851 ENSG00000124762 ENSG00000134480 ENSG00000093009 ENSG00000113558 ENSG00000136997 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000112742 ENSG00000139687 ENSG00000108055 ENSG00000175793 ENSG00000116717 ENSG00000117399 ENSG00000149311 ENSG00000145604 ENSG00000094804 ENSG00000134057 ENSG00000198176 ENSG00000135446 ENSG00000132646 ENSG00000004897 ENSG00000149554 ENSG00000080839 ENSG00000175305 PMC6828713__F1 Otub1-mediated regulation of the IL-15 signaling pathway ENSG00000198793 ENSG00000164136 PMC8499812__F6 DeepDRIM: a deep neural network to reconstruct cell-type-specific gene regulatory network using single-cell RNA-seq data ENSG00000110031 ENSG00000128951 ENSG00000173141 ENSG00000112335 ENSG00000161405 ENSG00000155926 ENSG00000196839 ENSG00000165280 ENSG00000160710 ENSG00000081189 ENSG00000164305 ENSG00000164104 ENSG00000161960 ENSG00000010244 ENSG00000176083 ENSG00000067066 ENSG00000011304 ENSG00000167468 ENSG00000168374 ENSG00000124201 ENSG00000282899 ENSG00000185088 PMC6521935__F7 Mechanism of salidroside-induced apoptosis, cell cycle arrest and suppressed invasion of osteosarcoma cells via inhibition of the JAK2/STAT3 signaling pathway ENSG00000168610 PMC8698620__F8 Murine Neonatal Oxidant Lung Injury: NRF2-Dependent Predisposition to Adulthood Respiratory Viral Infection and Protection by Maternal Antioxidant ENSG00000149573 ENSG00000166477 ENSG00000105327 ENSG00000244694 ENSG00000157601 ENSG00000186480 ENSG00000122877 ENSG00000137270 ENSG00000174996 ENSG00000116017 ENSG00000104320 ENSG00000101654 ENSG00000139687 ENSG00000062485 ENSG00000178860 ENSG00000185022 ENSG00000157005 ENSG00000084764 ENSG00000169220 ENSG00000110841 ENSG00000109805 ENSG00000125675 ENSG00000172005 ENSG00000139116 ENSG00000185339 ENSG00000110921 ENSG00000145365 ENSG00000101447 ENSG00000168811 ENSG00000166592 ENSG00000197063 ENSG00000064607 ENSG00000150051 ENSG00000126458 ENSG00000106178 ENSG00000148346 ENSG00000023516 ENSG00000175793 ENSG00000184661 ENSG00000132467 ENSG00000157833 ENSG00000149218 ENSG00000104983 ENSG00000150201 ENSG00000183891 ENSG00000158055 ENSG00000171872 ENSG00000072786 ENSG00000015285 ENSG00000143322 PMC7387650__F3 Regulation on the suppressive nature of MDSCs by subset composition and the tumor microenvironment ENSG00000101751 ENSG00000198793 ENSG00000118520 ENSG00000049768 PMC5402913__F1 Profile of romosozumab and its potential in the management of osteoporosis ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000167074 PMC3696710__F1 Constitutive components and the transduced mechanisms of Hh signaling pathway ENSG00000180447 ENSG00000106571 ENSG00000128602 PMC8001022__F2 RAGE structure and signaling pathway ENSG00000239732 ENSG00000189403 ENSG00000172936 ENSG00000166278 ENSG00000150455 PMC11021430__F5 Representative scheme illustrating regulatory mechanisms of PTEN in BMSCs ENSG00000149311 ENSG00000175054 ENSG00000128917 ENSG00000178573 ENSG00000134982 ENSG00000198793 ENSG00000171462 ENSG00000090932 PMC11021430__F7 Representative scheme illustrating regulatory mechanisms of PTEN in HSCFs, SCs, ISCs and SSCs ENSG00000152348 ENSG00000157404 ENSG00000283780 ENSG00000291971 ENSG00000133116 ENSG00000150907 ENSG00000144848 ENSG00000145782 ENSG00000146648 ENSG00000057663 PMC11021430__F6 Representative scheme illustrating regulatory mechanisms of PTEN in RPCs ENSG00000198793 ENSG00000169047 ENSG00000168036 ENSG00000164690 ENSG00000273529 ENSG00000114315 ENSG00000128602 ENSG00000281857 ENSG00000136826 PMC3545532__F2 Model depicting the canonical Nrf2 stress response pathway in each of the different phases: basal, preinduction, induction, postinduction ENSG00000010810 ENSG00000156273 PMC5977125__F1 Overview of the cap-dependent translation initiation ENSG00000163435 ENSG00000120690 ENSG00000198793 ENSG00000100664 PMC9425624__F2 Mast Cells in the Pathogenesis of Pruritus in Mastocytosis ENSG00000132329 ENSG00000183695 ENSG00000078747 ENSG00000064989 PMC1995566__F7 Oxidative stress initiates a cascade of reactions leading to cell death via one or more sequences of molecular events ENSG00000132906 ENSG00000002330 ENSG00000164305 PMC6049067__F6 MiR‐26a‐5p as a novel HB repressor ENSG00000087586 ENSG00000187772 ENSG00000132341 PMC4081859__F2A Complement regulation of T cell immunity ENSG00000134982 PMC8050425__F5 Can1 and Mup1 endocytic pathways triggered by distinct signals ENSG00000171444 PMC7215397__F3A Prenatal S-Adenosine Methionine (SAMe) Induces Changes in Gene Expression in the Brain of Newborn Mice That Are Prevented by Co-Administration of Valproic Acid (VPA) ENSG00000128052 ENSG00000089159 PMC9120625__F6 Antidepressant-like effect of ginsenoside Rb1 on potentiating synaptic plasticity via the miR-134–mediated BDNF signaling pathway in a mouse model of chronic stress-induced depression ENSG00000168036 ENSG00000139687 PMC6206761__F2 Interconnected responsible pathways to cause amyloid and tau accumulation ENSG00000284816 ENSG00000203710 ENSG00000198087 ENSG00000120885 ENSG00000073921 PMC6104488__F2 Schematic illustration of the PTEN regulated PI3K-AKT-mTOR signaling pathways in CNS axon regeneration PMC8469189__F2 Oral Cavity as a Source of Mesenchymal Stem Cells Useful for Regenerative Medicine in Dentistry ENSG00000178860 ENSG00000026103 PMC11563972__F3 Curcumin in the treatment of Parkinson’s disease (PD) ENSG00000168036 ENSG00000136869 ENSG00000079999 PMC11588630__F1 AIM2 inflammasome activation signaling pathway ENSG00000154451 ENSG00000278718 ENSG00000183735 ENSG00000164430 ENSG00000117228 ENSG00000105397 ENSG00000163568 PMC3936406__F1 Molecular signaling pathways mediated by MET receptor tyrosine kinase in neurons ENSG00000167601 ENSG00000019991 ENSG00000070831 ENSG00000291971 ENSG00000198793 ENSG00000163914 ENSG00000026508 ENSG00000099942 ENSG00000168610 PMC7809845__F4 Prolactin signaling pathway (KEGG ID: hsa04917) ENSG00000117020 ENSG00000291971 ENSG00000129946 ENSG00000114737 ENSG00000173039 ENSG00000118971 ENSG00000113494 PMC12178017__F6 EGb761 suppressed vascular dementia via modulating Wnt/Beta-catenin signaling pathway-induced apoptosis and autophagy in hippocampal neuronal cells ENSG00000284099 ENSG00000112561 ENSG00000237693 PMC2045624__F1 OX40 signaling directly triggers the antitumor effects of NKT cells ENSG00000158473 PMC5221490__F6 Intrinsic and extrinsic factors used during vertebrate lens development ENSG00000170365 ENSG00000182968 ENSG00000107859 ENSG00000281324 ENSG00000168214 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000117707 ENSG00000114315 PMC4613668__F2 MAPK/JNK signalling: a potential autophagy regulation pathway ENSG00000110497 ENSG00000083290 ENSG00000145782 ENSG00000057663 PMC4148035__F6 A negative feedback role of miR-326 in the Shh signaling pathway ENSG00000164690 ENSG00000128602 PMC7584566__F5 Schemes depicting hormonal axes involving insulin-producing cells (IPCs) in adult flies ENSG00000134982 ENSG00000258429 PMC8222562__F1 SCR7, a potent cancer therapeutic agent and a biochemical inhibitor of nonhomologous DNA end‐joining ENSG00000051180 PMC11588630__F4 Regulatory mechanism of AIM2 in tumor cell proliferation and migration ENSG00000163568 ENSG00000198793 ENSG00000168610 PMC11588630__F3 Regulatory mechanism of AIM2 in inflammatory response ENSG00000169245 ENSG00000186810 ENSG00000163568 ENSG00000198793 ENSG00000136997 ENSG00000091106 ENSG00000125347 PMC11588630__F2 Other signaling pathways of AIM2 ENSG00000162594 ENSG00000278718 ENSG00000162711 ENSG00000164430 ENSG00000163568 ENSG00000137265 ENSG00000168040 ENSG00000168404 ENSG00000285379 ENSG00000115594 PMC6150497__F3 Biologically anchored knowledge expansion approach uncovers KLF4 as a novel insulin signaling regulator ENSG00000104812 ENSG00000204842 ENSG00000169047 ENSG00000136111 ENSG00000164327 ENSG00000084733 ENSG00000089902 ENSG00000136826 ENSG00000105723 PMC7600282__F4 Target points of the dietary compounds on mitochondrial dynamics and mitogenesis, with a particular focus on mitophagy ENSG00000175193 ENSG00000198742 ENSG00000150907 ENSG00000198793 ENSG00000144848 ENSG00000158828 ENSG00000069509 ENSG00000112561 ENSG00000142082 ENSG00000106459 ENSG00000214253 PMC6876298__F2 Dysregulation of the complement cascade in C3 glomerulopathy ENSG00000203710 ENSG00000117335 ENSG00000244731 ENSG00000117322 ENSG00000182326 ENSG00000062485 ENSG00000236625 PMC2993855__F2 Pathways correcting DNA polymerase errors ENSG00000113318 ENSG00000095002 ENSG00000122512 PMC4511812__F1 Hematologic malignancies: at the forefront of immunotherapeutic innovation ENSG00000134982 ENSG00000189403 ENSG00000104432 ENSG00000168685 PMC6057898__F3 Interplay between melatonin and clock genes in joint during OA ENSG00000139219 ENSG00000125398 ENSG00000165030 ENSG00000157766 ENSG00000125538 ENSG00000132326 ENSG00000179094 ENSG00000096717 PMC7280868__F1 Canonical autophagy pathway ENSG00000152348 ENSG00000070540 ENSG00000157954 ENSG00000145782 ENSG00000057663 PMC11855613__F1 Diagrams summing up the pathogenetic pathways relevant to BBB disruption in TBE and discussed in the paper ENSG00000137673 ENSG00000149968 ENSG00000100985 PMC8276315__F8 Small-molecule modulators of INAVA cytosolic condensate and cell–cell junction assemblies ENSG00000167207 ENSG00000163362 ENSG00000198793 ENSG00000175104 PMC3405863__F4 EGFR pathway in Drosophila ENSG00000146648 PMC2721689__F1 Structural and functional modules in RNA interference ENSG00000169397 ENSG00000128191 ENSG00000113360 PMC3405863__F5 Segmentation clock oscillator ENSG00000281324 ENSG00000198435 ENSG00000134982 ENSG00000179111 ENSG00000168036 ENSG00000273529 ENSG00000114315 ENSG00000106003 PMC3513309__F3 Gene Expression Profile of Peripheral Blood Lymphocytes from Renal Cell Carcinoma Patients Treated with IL-2, InterferonA and Dendritic Cell Vaccine ENSG00000177455 ENSG00000070831 ENSG00000007312 ENSG00000198793 ENSG00000113263 ENSG00000135605 PMC8799543__F2 Macrophage migration inhibitory factor family proteins are multitasking cytokines in tissue injury ENSG00000110700 ENSG00000019582 ENSG00000162711 ENSG00000125538 ENSG00000026508 ENSG00000144476 PMC3970144__F6 HCV assembly involves a concerted action of all viral proteins and hijacks the host lipoprotein synthesis pathway ENSG00000285482 PMC7365859__F1 Legend: A schematic view of the involvement of zinc in various signaling pathways ENSG00000136997 PMC6704288__F5 Proposed model of the combined effect of ROR1 inhibition and erlotinib treatment in non-small cell lung cancer cell lines via inhibition of the AKT/mTOR signaling pathway ENSG00000169047 ENSG00000198793 ENSG00000185483 ENSG00000146648 PMC6115979__F3 TRPM7 kinase in T cell signalling and transcriptional regulation ENSG00000092439 ENSG00000083457 ENSG00000168610 PMC6932917__F10 RXFP3 in DNA damage response and repair ENSG00000143799 ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000288474 ENSG00000277069 ENSG00000051180 ENSG00000253729 ENSG00000139618 PMC3513309__F4 Gene Expression Profile of Peripheral Blood Lymphocytes from Renal Cell Carcinoma Patients Treated with IL-2, InterferonA and Dendritic Cell Vaccine ENSG00000122025 ENSG00000033327 ENSG00000291603 ENSG00000002330 ENSG00000070831 ENSG00000285109 ENSG00000100387 ENSG00000163599 ENSG00000186716 ENSG00000198793 ENSG00000010671 PMC3103499__F3 Computational Identification of Transcriptional Regulators in Human Endotoxemia ENSG00000131473 ENSG00000081041 ENSG00000119535 ENSG00000125538 ENSG00000163083 ENSG00000173535 ENSG00000099326 ENSG00000146701 ENSG00000090376 ENSG00000115009 ENSG00000026103 PMC8604044__F2 Dysregulation of Neuronal Nicotinic Acetylcholine Receptor–Cholesterol Crosstalk in Autism Spectrum Disorder ENSG00000113161 ENSG00000104549 PMC5828651__F5 RNA-editing regulated genes in LUAD are enriched in apoptosis and innate immune-related genes ENSG00000088888 ENSG00000026103 ENSG00000160049 PMC7870930__F3 Progress in understanding the role of lncRNA in programmed cell death ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC6307844__F1 Pathways participate in tumourigenesis of CCA ENSG00000134982 ENSG00000168036 PMC3809585__F3 TAM-regulated cycle of inflammation in dendritic cells ENSG00000167601 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC7904626__F1 Biosynthetic pathway of oxetanocin-A (1) ENSG00000182511 ENSG00000110395 PMC3809585__F2 TAM receptor signaling pathways ENSG00000115415 PMC4977063__F7 Model deciphering the signalling pathway hijacked by EspT leading to induction of inflammatory responses in macrophages ENSG00000070831 ENSG00000125538 PMC9522918__F4 Metabolic remodeling of pyrimidine synthesis pathway and serine synthesis pathway in human glioblastoma PMC11351628__F1 PPAR targets and contributing factors in MASLD/MASH ENSG00000130304 ENSG00000135218 ENSG00000042832 ENSG00000138823 ENSG00000112561 ENSG00000124003 ENSG00000113790 ENSG00000062282 ENSG00000026103 PMC8261853__F2 Host Modulation and Treatment of Periodontal Disease ENSG00000168036 PMC4174666__F4 Generation of a biological network of genes related to the upstream regulator IRF2 ENSG00000105835 ENSG00000123609 ENSG00000105697 ENSG00000130589 ENSG00000168310 ENSG00000162692 ENSG00000163737 ENSG00000125347 ENSG00000168610 ENSG00000135919 PMC6794554__F1 Wnt signaling with two intersecting networks: Canonical Wnt (or Beta-catenin-dependent) and non-canonical Wnt (or Beta-catenin-independent) pathways ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000070831 ENSG00000134982 ENSG00000058091 ENSG00000185483 ENSG00000168036 PMC7515827__F2 Metabolic rewiring in the promotion of cancer metastasis: mechanisms and therapeutic implications ENSG00000188641 ENSG00000131473 ENSG00000117480 ENSG00000122691 ENSG00000170558 ENSG00000113161 ENSG00000146648 ENSG00000070669 PMC6927537__F2 Kinase alterations and signaling pathways dysregulated in Ph-like ALL ENSG00000100385 ENSG00000182578 ENSG00000122025 ENSG00000105397 ENSG00000198793 ENSG00000134853 ENSG00000143322 ENSG00000292363 ENSG00000099942 ENSG00000105639 ENSG00000077782 ENSG00000127948 PMC7766727__F3 PI3K/AKT signaling pathway with plant-based inhibitors (created by BioRender.com) ENSG00000281324 ENSG00000002330 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000168040 ENSG00000026103 PMC8507398__F10 Molecular biology of autoinflammatory diseases ENSG00000167207 ENSG00000137275 ENSG00000102871 ENSG00000082512 ENSG00000172936 ENSG00000083799 ENSG00000150455 ENSG00000154124 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC7084529__F11 Altered sphingolipid and gene transcript levels in ASAH1KD SH-SY5Y cells ENSG00000139624 ENSG00000100422 ENSG00000198964 ENSG00000223802 ENSG00000143753 ENSG00000188611 ENSG00000119537 ENSG00000078124 ENSG00000285281 ENSG00000143418 ENSG00000135587 PMC12144744__F4 Antitumour mechanisms of statins ENSG00000183735 ENSG00000137033 ENSG00000163914 ENSG00000197429 ENSG00000113161 ENSG00000145321 ENSG00000168036 PMC12144744__F1 Mechanism linking dyslipidaemia and gastric cancer ENSG00000102962 ENSG00000135218 ENSG00000291971 ENSG00000102970 ENSG00000145321 ENSG00000171791 ENSG00000162692 ENSG00000168610 ENSG00000106178 ENSG00000150630 PMC4842340__F2 Involvement of the prohibitin (PHB/PHB1) in granulosa cell (GCs) survival and differentiation functions ENSG00000171791 PMC8887676__F7 Therapeutic potential of the PI3K/AKT/mTOR axis for the management of AD and cancer ENSG00000198793 ENSG00000123374 PMC3675076__F5 Gli2 Acetylation at Lysine 757 Regulates Hedgehog-Dependent Transcriptional Output by Preventing Its Promoter Occupancy ENSG00000128602 PMC5003605__F1 Metabolic pathways and genes involved in the utilization of nonfermentable carbons ENSG00000180210 ENSG00000101193 ENSG00000124253 ENSG00000146701 PMC4730127__F3 Targeting of the genes and pathways for stem cell maintenance by miR-200 family miRNAs ENSG00000168283 ENSG00000169554 ENSG00000184384 ENSG00000168036 ENSG00000196782 PMC3590494__F4 Significant molecular network of combination therapy related metabolites ENSG00000165983 ENSG00000157933 PMC7303382__F8 Neuroactive ligand–receptor interaction pathway ENSG00000122420 ENSG00000248329 ENSG00000102539 ENSG00000198670 ENSG00000121853 ENSG00000075073 ENSG00000010310 ENSG00000196689 PMC6423002__F1 AMPK/Ulk1-dependent autophagy as a key mTOR regulator in the context of cell pluripotency ENSG00000177169 ENSG00000125285 ENSG00000198793 PMC11894577__F8 KEGG website to retrieve a map of the key pathways of CE action in ovarian cancer ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000136869 PMC7063117__F3 Regulatory role of miRNAs in OP-associated pathways ENSG00000157554 ENSG00000281324 ENSG00000110395 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000099194 ENSG00000175104 ENSG00000146648 ENSG00000131196 PMC8035314__F3 Signaling via the IR and IGF-1R ENSG00000002330 PMC8151052__F1 Targeting the Fibroblast Growth Factor Receptor (FGFR) Family in Lung Cancer ENSG00000110395 PMC8035314__F2 Functional outcomes of the IR/IGF-1R/IRS pathway in normal and breast cancer settings ENSG00000129214 ENSG00000140443 PMC3590501__F6 Proposed mechanism for the protective effects of carvacrol against hepatic steatosis in mice ENSG00000160752 ENSG00000135218 ENSG00000170458 ENSG00000172893 ENSG00000198793 ENSG00000113161 ENSG00000172936 ENSG00000026103 PMC9618889__F6 Major pathways involved in macrophage polarization in cancer ENSG00000291971 ENSG00000168610 PMC7407119__F2 The antioxidative landscape in the cell, and the corresponding modulators of key players ENSG00000175793 ENSG00000079999 PMC6509080__F2 Mechanistic pathways underlying reverse cholesterol transport from macrophages to liver ENSG00000130164 ENSG00000042832 ENSG00000100979 ENSG00000160179 PMC7407119__F1 The major sources of reactive oxygen species (ROS) in the cell and the corresponding inhibitors of those sites ENSG00000197930 ENSG00000086991 ENSG00000102967 PMC5854933__F1 WNT pathway ENSG00000165556 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167874 ENSG00000168036 ENSG00000154310 ENSG00000086758 ENSG00000155760 ENSG00000165617 PMC7299226__F6 Metabolic pathway showing lysoPL (lysophosphospholipids)/lysoPA (lysophosphatidic acid) regulatory genes that are significantly altered by ANRIL knockdown in HEK cells.Genes that metabolize these lipids are shown ENSG00000065357 ENSG00000105499 ENSG00000067113 ENSG00000141934 ENSG00000087253 ENSG00000136960 ENSG00000173599 ENSG00000105520 ENSG00000111684 ENSG00000121316 ENSG00000146070 ENSG00000153395 ENSG00000164398 ENSG00000177666 PMC5877728__F1 Overview of the stress-activated protein kinase (SAPK) pathway ENSG00000291603 ENSG00000154310 PMC4005386__F2 Signaling networks for brain, lung, and bone metastases of breast cancer ENSG00000104365 ENSG00000282905 ENSG00000070831 ENSG00000109320 ENSG00000164587 ENSG00000269335 ENSG00000095015 ENSG00000196591 ENSG00000173039 ENSG00000177954 ENSG00000162924 ENSG00000101224 ENSG00000121774 ENSG00000291420 ENSG00000174444 ENSG00000148396 ENSG00000101945 ENSG00000092621 ENSG00000010810 ENSG00000128052 ENSG00000011243 ENSG00000124171 ENSG00000198625 ENSG00000280548 PMC7738904__F1 Essentials of TGFB signaling pathway PMC2854249__F2 Mammalian autophagy: core molecular machinery and signaling regulation ENSG00000002330 ENSG00000169047 PMC4960093__F3 General summary of altered mitochondrial functions in cancer cell life and death ENSG00000136997 ENSG00000171791 PMC3495133__F1 Schematic of the desaturation and elongation biosynthetic pathway of essential dietary fatty acids to longer chain fats ENSG00000134824 ENSG00000149485 PMC2854249__F1 Mammalian autophagy: core molecular machinery and signaling regulation ENSG00000177169 ENSG00000110497 ENSG00000198382 ENSG00000078804 ENSG00000062716 PMC4699388__F7 Overexpression of E2F-2 abolishes the PPP-mediated inhibition of terminal differentiation in Gata1S310A erythroid cells ex vivo ENSG00000153487 ENSG00000158578 ENSG00000140443 PMC7946848__F3 Possible roles of circRNAs in SLE ENSG00000144895 ENSG00000135828 PMC5869074__F1 Cross-talk between protein synthesis, energy metabolism and autophagy in cancer ENSG00000177169 ENSG00000123395 ENSG00000128272 ENSG00000144895 ENSG00000169047 ENSG00000284161 ENSG00000167658 ENSG00000145782 PMC11774878__F4 Functions of non-coding RNAs that target ferroptosis and EMT in TNBC metastasis ENSG00000126858 ENSG00000151012 ENSG00000167468 ENSG00000168610 PMC8983758__F2 Feedlot diets containing different starch levels and additives change the cecal proteome involved in cattle’s energy metabolism and inflammatory response ENSG00000125166 ENSG00000130957 ENSG00000143158 ENSG00000160883 ENSG00000059804 ENSG00000108515 ENSG00000067057 ENSG00000288174 ENSG00000131828 ENSG00000163114 ENSG00000074800 ENSG00000173599 ENSG00000110435 ENSG00000164708 ENSG00000124253 ENSG00000136872 ENSG00000146701 ENSG00000091140 ENSG00000159399 ENSG00000152556 ENSG00000060762 PMC11774878__F3 Crosstalk between ferroptosis and EMT in TNBC metastasis ENSG00000186575 ENSG00000065911 ENSG00000122691 ENSG00000170558 ENSG00000167468 ENSG00000072274 ENSG00000150457 ENSG00000131023 PMC1857267__F2 Altered macrophage differentiation and immune dysfunction in tumor development ENSG00000172216 ENSG00000118520 ENSG00000105639 ENSG00000007171 PMC8036852__F3 Brucella can inhibit the secretion of IL-2 by antigen presenting cells, and then prevent natural killer cells (NK) from secreting inflammatory factors such as IFNG and TNFA ENSG00000134982 PMC11774878__F2 EMT in TNBC metastasis ENSG00000137807 ENSG00000144642 ENSG00000116132 ENSG00000275272 PMC8482137__F4 Differential Expression of Non-Coding RNA Signatures in Thyroid Cancer between Two Ethnic Groups ENSG00000271271 ENSG00000275190 ENSG00000244474 ENSG00000174684 ENSG00000197165 ENSG00000173610 PMC8482137__F3 Differential Expression of Non-Coding RNA Signatures in Thyroid Cancer between Two Ethnic Groups ENSG00000177606 ENSG00000136997 ENSG00000169429 ENSG00000169032 PMC3962195__F1 Biological processes and genes implicated in the Parkinson's disease ENSG00000132906 ENSG00000164305 ENSG00000174611 ENSG00000115317 PMC2907698__F4 An example of combined analysis of three identified regulatory modules ENSG00000002330 ENSG00000157764 ENSG00000120875 ENSG00000130522 ENSG00000183943 ENSG00000132646 ENSG00000163914 ENSG00000177606 ENSG00000143933 ENSG00000171791 ENSG00000146648 ENSG00000026103 PMC7279161__F4 Comparison of Nrf1 and sterol regulatory element-binding protein (SREBP) activation pathway ENSG00000197312 ENSG00000178573 ENSG00000151092 ENSG00000106459 PMC3972652__F1 Biosynthesis pathway for gangliosides ENSG00000257218 ENSG00000069482 ENSG00000111728 PMC5424241__F5 Leukocyte extravasation signaling pathway ENSG00000087245 ENSG00000137673 ENSG00000168036 ENSG00000132478 ENSG00000158517 ENSG00000116701 ENSG00000257335 ENSG00000010671 ENSG00000121966 ENSG00000089159 ENSG00000292348 ENSG00000156103 ENSG00000166501 ENSG00000026508 ENSG00000074966 ENSG00000154721 ENSG00000013297 ENSG00000113263 ENSG00000100985 ENSG00000115232 ENSG00000100365 ENSG00000135605 PMC3731064__F2 Chromatin and the genome integrity network ENSG00000138346 ENSG00000101773 ENSG00000197299 PMC8753987__F6 Top-Down Enrichment Strategy to Co-cultivate Lactic Acid and Lignocellulolytic Bacteria From the Megathyrsus maximus Phyllosphere ENSG00000197713 ENSG00000047597 PMC12179905__F1 Pathways of apoptosis ENSG00000128272 ENSG00000026103 PMC8148105__F1 IDARE2—Simultaneous Visualisation of Multiomics Data in Cytoscape ENSG00000245848 ENSG00000039537 ENSG00000171759 ENSG00000166278 ENSG00000132170 PMC12179905__F2 Common signaling pathways affecting apoptosis: Phosphatidylinositol 3-kinases/protein kinase B/mammalian target of rapamycin signaling pathway and wnt/Beta-catenin signaling pathway ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC3433899__F3 Single gene and protein network generated by Approach 3 (Network 1) that demonstrated significance as a clinical relapse predictor following a stringent permutation based test ENSG00000143799 ENSG00000064666 ENSG00000131473 ENSG00000143320 ENSG00000167996 ENSG00000187955 ENSG00000236625 PMC3977653__F1 At Loose Ends: Resecting a Double-Strand Break ENSG00000138346 ENSG00000051180 PMC3406577__F6 Restoration of cell death by ABT-737 in cancer cells that overexpress Bcl-2 and caspase activity is blocked ENSG00000115317 PMC6007953__F1 XIAP regulates apoptotic and inflammatory signaling pathways ENSG00000167207 ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC8567306__F5 Clinical translation of immunomodulatory therapeutics ENSG00000105639 PMC7567935__F15 Pre-treatment of rats with melatonin (10 mg/kg bw) prior to ISO treatment (25 mg/kg bw) prevented occurrence of myocardial infarction and averted mitochondrial dysfunction caused by ISO mediated oxidative stress ENSG00000096088 ENSG00000096717 ENSG00000142082 ENSG00000167419 PMC5425951__F2 Ingenuity Pathway Analysis network showing the relationships between several assayed genes (emphasized with black arrows) ENSG00000224320 ENSG00000101160 ENSG00000105397 ENSG00000187908 ENSG00000132514 ENSG00000186818 PMC10933033__F3 Pro-inflammatory cytokine expression by interleukin receptors via STAT and IRF transcription factors ENSG00000115415 ENSG00000137265 PMC10933033__F2 TOLLIP-mediated regulation of IL-1R signaling ENSG00000175104 ENSG00000184216 PMC5149546__F7 Putative triterpenoid saponins biosynthesis pathway in A ENSG00000067064 ENSG00000197429 PMC6291243__F2 Biosynthesis of the ADR-GlyU disaccharide core 17a ENSG00000204020 ENSG00000204021 ENSG00000173239 PMC4864225__F3 Hypothesis on skeletal muscle adiponectin resistance in chronic heart failure ENSG00000150907 ENSG00000159346 ENSG00000096717 PMC10933033__F4 Adaptor protein SLAP-2 regulates CSF1R-mediated differentiation and survival of macrophages ENSG00000182578 ENSG00000033327 PMC2997336__F1 Model illustrating the signaling pathways activated by optimal DA and hyperdopamine ENSG00000168036 PMC8476809__F2 Skeletal Muscle Deconditioning in Breast Cancer Patients Undergoing Chemotherapy: Current Knowledge and Insights From Other Cancers ENSG00000009709 ENSG00000177169 ENSG00000128272 ENSG00000144895 ENSG00000116688 ENSG00000198793 ENSG00000158828 ENSG00000145782 ENSG00000057663 ENSG00000214253 PMC10933033__F1 Adaptor proteins mediating the signaling of TLR receptors ENSG00000167941 ENSG00000146094 ENSG00000172936 ENSG00000136869 ENSG00000115295 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC8135095__F1 Microglia: A Double-Edged Sword in Intracerebral Hemorrhage From Basic Mechanisms to Clinical Research ENSG00000111537 ENSG00000115415 ENSG00000136869 PMC8044534__F2 Diverse range of signals in the TME which could induce HMOX1 expression ENSG00000168610 ENSG00000156273 ENSG00000079999 PMC8392882__F5 Critical Role of Growth Factors in Gastric Ulcer Healing: The Cellular and Molecular Mechanisms and Potential Clinical Implications ENSG00000138798 PMC3035360__F1 Synthetic view of the p53 pathway ENSG00000145632 ENSG00000127445 ENSG00000136997 ENSG00000140464 ENSG00000172201 PMC4329310__F4 Detailed view of protein secretion pathway ENSG00000136731 ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000079999 PMC9142883__F7 Metabolomics Study Suggests the Mechanism of Different Types of Tieguanyin (Oolong) Tea in Alleviating Alzheimer’s Disease in APP/PS1 Transgenic Mice ENSG00000196531 ENSG00000168925 ENSG00000141086 ENSG00000086730 PMC3933272__F4 WNT signaling pathway ENSG00000087095 ENSG00000090402 ENSG00000134982 PMC6015534__F1 Schematic describes the major developmental steps that underlie the differentiation of preskeletal mesenchymal cells toward endochondral (right) and intramembranous (left) ossification ENSG00000128272 ENSG00000125398 ENSG00000020633 ENSG00000291761 ENSG00000081189 ENSG00000110693 PMC11658145__F7 Schematic summary of the effects of PEVs on the MV3 and A2058 spheroids ENSG00000110651 ENSG00000010278 ENSG00000135404 ENSG00000132693 PMC8054189__F1 Aminoglycerophospholipid biosynthetic pathways in yeast, Saccharomyces cerevisiae ENSG00000163624 ENSG00000146005 ENSG00000173599 PMC7664432__F1 Complex regulation of E-cadherin expression ENSG00000128602 ENSG00000168610 PMC4380406__F1 Impact of Host Diet on Wolbachia Titer in Drosophila ENSG00000136997 PMC8220701__F1 Genome-wide expression and network analyses of mutants in key brassinosteroid signaling genes ENSG00000110934 ENSG00000163788 PMC9261067__F7 Circ-FOXM1 promotes the proliferation, migration and EMT process of osteosarcoma cells through FOXM1-mediated Wnt pathway activation ENSG00000087245 ENSG00000168036 ENSG00000100985 PMC7468828__F7 Monophosphoryl lipid A pretreatment suppresses sepsis- and LPS-induced proinflammatory cytokine production in the medullary thick ascending limb ENSG00000172936 ENSG00000136869 ENSG00000184216 PMC4800028__F1 CrossTalk proposal: Intramyocellular ceramide accumulation does modulate insulin resistance ENSG00000135218 ENSG00000159346 ENSG00000136869 ENSG00000285070 PMC11741906__F5 Effect of differentially expressed miRNAs related to cisplatin resistance on MAPK signaling pathway ENSG00000087095 ENSG00000117020 PMC7779440__F3 TNF Signaling Pathway (Retrieved from KEGG) as One of the Pathways of Brazilin Targets in Metastatic Breast Cancer ENSG00000078747 ENSG00000157227 ENSG00000196549 ENSG00000007908 ENSG00000128342 ENSG00000168040 ENSG00000164305 PMC3097535__F5 Global gene expression and Ingenuity biological functions analysis on PCB 153 and 138 induced human PBMC in vitro reveals differential mode(s) of action in developing toxicities ENSG00000115415 ENSG00000080644 PMC8305863__F2 Of helper-dependent Adenoviral vectors in CRISPR-cas9-mediated lung gene therapy ENSG00000150782 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000167207 ENSG00000134982 ENSG00000186716 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000276561 PMC3097535__F4 Global gene expression and Ingenuity biological functions analysis on PCB 153 and 138 induced human PBMC in vitro reveals differential mode(s) of action in developing toxicities ENSG00000169862 ENSG00000164251 ENSG00000198242 PMC11171836__F11 Mechanism by which Pin1 regulates NAFLD ENSG00000127445 ENSG00000169710 PMC6700826__F7 Putative regulatory pattern of PoSet1 and PoSet2 on cellulolytic enzyme gene expression ENSG00000151376 ENSG00000065833 ENSG00000082212 PMC8870972__F3A Eutopic Endometrium Proteome in Endometriosis Reveals Candidate Markers and Molecular Mechanisms of Physiopathology ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000104894 PMC3165467__F6 Results of Ingenuity pathway analysis ENSG00000277571 PMC3878201__F4 miR-34a mediates paclitaxel resistance via both direct and indirect mechanisms ENSG00000169554 ENSG00000105810 ENSG00000171791 ENSG00000096717 PMC12075250__F2 AECAs pro-apoptotic and pro-inflammatory effects in ECs ENSG00000168040 ENSG00000162692 ENSG00000026103 PMC1770611__F2 Axin in Wnt signalling ENSG00000134982 ENSG00000168036 PMC6328866__F3 Gene expression profiles analysis identifies a novel two-gene signature to predict overall survival in diffuse large B-cell lymphoma ENSG00000130338 ENSG00000138136 ENSG00000154027 ENSG00000213160 ENSG00000105835 ENSG00000185915 ENSG00000197756 ENSG00000130182 ENSG00000171612 ENSG00000109906 ENSG00000176533 ENSG00000100346 ENSG00000104921 ENSG00000170802 ENSG00000262634 ENSG00000137807 ENSG00000059573 ENSG00000139278 ENSG00000172794 ENSG00000035499 ENSG00000164109 ENSG00000009790 ENSG00000126787 ENSG00000161055 ENSG00000111816 ENSG00000274473 ENSG00000117399 ENSG00000129173 ENSG00000122952 ENSG00000156970 ENSG00000101003 ENSG00000143476 ENSG00000280610 ENSG00000132646 ENSG00000180543 ENSG00000165462 ENSG00000165480 ENSG00000010818 ENSG00000134575 ENSG00000101447 ENSG00000256683 ENSG00000099822 ENSG00000117602 ENSG00000120539 ENSG00000276825 ENSG00000112578 ENSG00000124795 ENSG00000136235 ENSG00000215845 ENSG00000071539 ENSG00000106305 ENSG00000112742 ENSG00000112486 ENSG00000134690 ENSG00000111247 ENSG00000137547 ENSG00000138622 ENSG00000101057 ENSG00000145040 ENSG00000140259 ENSG00000143228 ENSG00000175857 ENSG00000065328 ENSG00000111231 ENSG00000024526 ENSG00000171848 ENSG00000178015 ENSG00000110665 ENSG00000197933 ENSG00000167971 ENSG00000152518 ENSG00000182557 PMC10750287__F4 Cross-Communication of Cuproptosis and Regulated Cell Death in Human Pathophysiology ENSG00000278718 ENSG00000162711 ENSG00000091106 ENSG00000064012 ENSG00000164305 PMC8634458__F1 Therapeutic Development by Targeting the cGAS-STING Pathway in Autoimmune Disease and Cancer ENSG00000183735 ENSG00000164430 PMC10750287__F6 Molecular mechanisms of autophagy triggered by excess Cu ENSG00000180210 ENSG00000177169 ENSG00000173992 ENSG00000138495 ENSG00000198793 ENSG00000123191 ENSG00000177556 ENSG00000133028 ENSG00000284194 ENSG00000079999 PMC11741906__F4 Effect of differentially expressed miRNAs related to cisplatin resistance on PI3K-Akt signaling pathway ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 PMC8071856__F1 Endothelial and Vascular Functions by Carbon Monoxide via Crosstalk With Nitric Oxide ENSG00000105835 ENSG00000096717 ENSG00000106459 PMC8898094__F4 Kinase-Catalyzed Biotinylation to Map Cell Signaling Pathways: Application to Epidermal Growth Factor Signaling ENSG00000148606 ENSG00000134371 ENSG00000166685 ENSG00000173599 ENSG00000149273 ENSG00000058668 ENSG00000148175 ENSG00000077312 ENSG00000122140 ENSG00000185825 ENSG00000166441 ENSG00000157827 ENSG00000113649 ENSG00000106803 ENSG00000173933 ENSG00000070961 ENSG00000111530 ENSG00000130811 ENSG00000124802 ENSG00000158941 ENSG00000154124 ENSG00000120063 ENSG00000101161 ENSG00000100836 ENSG00000112208 ENSG00000175390 ENSG00000130726 ENSG00000165280 ENSG00000150093 ENSG00000198700 ENSG00000107581 ENSG00000131238 ENSG00000100354 ENSG00000104980 ENSG00000205937 ENSG00000215301 ENSG00000119471 ENSG00000074695 ENSG00000108828 ENSG00000127022 ENSG00000165219 ENSG00000172340 ENSG00000291420 ENSG00000131828 ENSG00000215021 ENSG00000196961 ENSG00000107371 ENSG00000138674 ENSG00000115524 ENSG00000106263 ENSG00000167996 ENSG00000011243 ENSG00000096401 ENSG00000137055 ENSG00000111642 ENSG00000100519 ENSG00000147649 ENSG00000108588 ENSG00000121940 ENSG00000103222 ENSG00000146963 ENSG00000281309 ENSG00000112118 ENSG00000048828 ENSG00000103257 ENSG00000076003 ENSG00000171262 ENSG00000170802 ENSG00000166508 ENSG00000130706 ENSG00000076554 ENSG00000165119 ENSG00000018510 ENSG00000105568 ENSG00000129173 ENSG00000100029 ENSG00000224320 ENSG00000265808 ENSG00000058262 ENSG00000175198 ENSG00000137992 ENSG00000080371 ENSG00000026508 ENSG00000166224 ENSG00000110435 ENSG00000185567 ENSG00000146648 ENSG00000104325 ENSG00000140319 ENSG00000167768 ENSG00000109606 ENSG00000037474 ENSG00000101558 ENSG00000197956 ENSG00000168259 ENSG00000163993 ENSG00000170515 ENSG00000102316 ENSG00000005339 ENSG00000274779 ENSG00000163902 ENSG00000126883 ENSG00000083312 ENSG00000073921 ENSG00000178718 ENSG00000102007 ENSG00000100941 ENSG00000152291 ENSG00000069345 ENSG00000087087 ENSG00000149480 PMC6873421__F2 MET amplification causes EGFR-TKI resistance by activating EGFR-independent phosphorylation of ErbB3 and consequent downstream activation of the PI3K/AKT pathway, providing a resistance mechanism that can bypass the effects of an EGFR-TKI ENSG00000065361 ENSG00000005882 ENSG00000146648 PMC4099115__F4 IPA metabolic interaction network of plasma metabolites having a significant correlation with polyp counts in association with aGenotypebyDietinteraction effect ENSG00000110711 ENSG00000142192 PMC4099115__F3 Metscape gene-compounds metabolic network views of top IPA canonical pathway and biological function/disease ENSG00000143799 ENSG00000109743 ENSG00000291803 ENSG00000161980 ENSG00000013503 ENSG00000168002 ENSG00000138617 ENSG00000132664 ENSG00000111339 ENSG00000178685 ENSG00000156219 ENSG00000167311 ENSG00000102699 ENSG00000107854 ENSG00000147669 ENSG00000100142 ENSG00000059378 ENSG00000041880 ENSG00000144231 ENSG00000047315 ENSG00000173273 ENSG00000111224 PMC2777340__F4 Drosophila insulin signaling pathway ENSG00000169291 ENSG00000164327 PMC1622797__F5 Proposed molecular model of dietary omega-3 fatty acid interference with IL-1 signaling pathways leading to COX-2 induction in EC ENSG00000169704 PMC9367715__F2 NRF2 and Mitochondrial Function in Cancer and Cancer Stem Cells ENSG00000083093 ENSG00000254986 ENSG00000100387 ENSG00000079999 PMC9367715__F1 NRF2 and Mitochondrial Function in Cancer and Cancer Stem Cells ENSG00000100387 ENSG00000079999 PMC5712004__F3 Model depicting targets of CHOP-dependent apoptosis ENSG00000144895 ENSG00000168040 PMC8966655__F6 Propofol Protects Myocardium From Ischemia/Reperfusion Injury by Inhibiting Ferroptosis Through the AKT/p53 Signaling Pathway ENSG00000151012 ENSG00000167468 PMC3961481__F1 Novel pathway links telomeres to NK-cell activity ENSG00000166340 ENSG00000149311 ENSG00000175054 ENSG00000182601 ENSG00000128513 PMC9108237__F11 MicroRNA-382 Promotes M2-Like Macrophage via the SIRPA/STAT3 Signaling Pathway in Aristolochic Acid-Induced Renal Fibrosis ENSG00000198053 ENSG00000118520 ENSG00000168610 PMC6315745__F1 Chemoresistance ENSG00000170558 ENSG00000150457 ENSG00000168610 ENSG00000131023 PMC9652818__F1 N6-methyladenosine (m6A) modifications in gynecologic cancers: mechanisms and therapeutic targeting ENSG00000145388 ENSG00000167601 ENSG00000253293 ENSG00000033178 ENSG00000135451 ENSG00000198492 ENSG00000137699 ENSG00000091542 ENSG00000057663 ENSG00000149658 ENSG00000184110 ENSG00000154678 ENSG00000165819 ENSG00000104081 PMC7924916__F1 Severe acute respiratory syndrome coronaviruses’ lifecycle and possible mechanisms of interference with p53 and its regulatory pathways ENSG00000166794 ENSG00000215021 ENSG00000117400 ENSG00000214285 PMC7795259__F1 Fibrosis related intracellular Ca2+signaling pathways ENSG00000198793 ENSG00000173599 PMC9652818__F3 N6-methyladenosine (m6A) modifications in gynecologic cancers: mechanisms and therapeutic targeting ENSG00000145388 ENSG00000198492 ENSG00000198793 ENSG00000169047 ENSG00000124766 ENSG00000091542 ENSG00000146457 ENSG00000242265 ENSG00000149658 ENSG00000040199 ENSG00000291387 ENSG00000186654 ENSG00000165819 ENSG00000140443 PMC8599155__F3 Transient Receptor Potential Vanilloid Subtype 1: Potential Role in Infection, Susceptibility, Symptoms and Treatment of COVID-19 ENSG00000130234 ENSG00000184012 ENSG00000196689 PMC7403443__F1 Crosstalk between intestine and liver in the pathophysiology of NAFLD ENSG00000159224 ENSG00000136869 ENSG00000267534 PMC1839882__F9 Schematic illustration of the principal signaling pathways that are affected by sodium arsenite (As) treatment ENSG00000157764 ENSG00000168610 ENSG00000146648 ENSG00000026103 PMC5368685__F2 Pro-inflammatory response through TLR: various antigenic molecules are recognized differentially by TLRs, which produce pro-inflammatory responses ENSG00000174125 ENSG00000239732 ENSG00000172936 ENSG00000136869 PMC12134845__F2 Amino acid metabolism in osteoporosis: Effects on the bone microenvironment and treatment strategies (Review) ENSG00000107562 ENSG00000171720 ENSG00000198793 ENSG00000168610 ENSG00000115419 ENSG00000106546 PMC12134845__F1 EAAs are crucial for osteoblast function; their deficiency activates MAPK signaling, causing cell cycle arrest, ROS accumulation, DNA damage and apoptosis ENSG00000108849 ENSG00000136997 ENSG00000131196 PMC6667378__F1 Graph representation of the Signaling by NOTCH2 pathway as extracted from the Reactome database ENSG00000013619 ENSG00000110492 ENSG00000214357 ENSG00000196782 ENSG00000184916 ENSG00000137845 ENSG00000150991 ENSG00000143801 ENSG00000018236 ENSG00000197530 ENSG00000138613 ENSG00000168214 ENSG00000283780 ENSG00000184384 ENSG00000128917 ENSG00000205155 ENSG00000101752 PMC5558095__F7 Noncanonical GLI1 signaling sustaining LAC growth and CSC maintenance ENSG00000164690 ENSG00000112715 ENSG00000128602 ENSG00000118257 ENSG00000118777 PMC4742232__F6 Estrogen Enhances the Cell Viability and Motility of Breast Cancer Cells through the ERAlpha-ΔNp63-Integrin B4 Signaling Pathway ENSG00000164690 PMC3966702__F7 ABCA1 expression and function can be induced by GPR119 to protect from atherosclerosis ENSG00000125538 ENSG00000147262 PMC7077540__F9 CXCL12 and receptor CXCR4/CXCR7 in placenta accrete spectrum disorders (PAS) ENSG00000107562 ENSG00000070831 ENSG00000163914 ENSG00000121966 PMC8348042__F2 Transient Receptor Potential Channels in the Epithelial-to-Mesenchymal Transition ENSG00000019991 ENSG00000187688 ENSG00000092439 ENSG00000144935 ENSG00000138798 ENSG00000019549 ENSG00000124766 ENSG00000168036 ENSG00000137672 ENSG00000072315 ENSG00000138741 PMC6126184__F6 Pathway diagram presenting chaetominine mode of action associated with cell cycle regulation in SW1116 and K562 cells ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000123374 PMC9695749__F7 Mulberry Leaf (Morus alba L.) Extracts and Its Chlorogenic Acid Isomer Component Improve Glucolipotoxicity-Induced Hepatic Lipid Accumulation via Downregulating miR-34a and Decreased Inflammation ENSG00000169710 ENSG00000096717 PMC4522377__F1 Multifaceted Control of DNA Repair Pathways by the Hypoxic Tumor Microenvironment ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000276618 ENSG00000144554 ENSG00000198586 PMC3607745__F2 Cytokine and downstream signalling pathways in liver ischaemia reperfusion injury ENSG00000169245 ENSG00000138378 ENSG00000136869 PMC4145026__F1 Non-coding RNA regulation of synaptic plasticity and memory: implications for aging ENSG00000100811 ENSG00000096717 PMC7866901__F1 Expression characteristics and prognostic roles of autophagy-related genes in gastric cancer ENSG00000152348 ENSG00000123395 ENSG00000126775 ENSG00000101460 ENSG00000023287 ENSG00000165861 ENSG00000258102 ENSG00000198925 ENSG00000057663 ENSG00000168010 ENSG00000062716 ENSG00000197769 ENSG00000144848 ENSG00000070540 ENSG00000181652 ENSG00000145782 ENSG00000177169 ENSG00000110497 ENSG00000083290 ENSG00000196455 ENSG00000148572 ENSG00000066739 ENSG00000157954 ENSG00000110046 ENSG00000034713 ENSG00000168038 ENSG00000139112 PMC8854490__F1 Variety of Nucleic Acid Species Are Sensed by cGAS, Implications for Its Diverse Functions ENSG00000183735 ENSG00000164430 PMC9222487__F8 Comparative Transcriptome Analysis of Organ-Specific Adaptive Responses to Hypoxia Provides Insights to Human Diseases ENSG00000136869 ENSG00000168610 PMC7697665__F4 Role of RNF11 in the NFKB signaling pathway ENSG00000183735 ENSG00000123091 ENSG00000102871 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000168040 ENSG00000175104 ENSG00000127191 ENSG00000121060 ENSG00000184216 PMC7658606__F6 Diagram showing the mechanism of Tanshinone IIA on EMT and metastasis in colorectal cancer ENSG00000134982 ENSG00000170558 ENSG00000168036 PMC7441421__F2 Signaling pathways mediated by CTHRC1 involved in the progression and metastasis of tumor ENSG00000163235 ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC5881740__F1 JAK-STAT signalling pathway ENSG00000111537 ENSG00000105397 ENSG00000105639 PMC5031078__F1 RAF/MEK dependence of KRAS mutant pancreatic ductal adenocarcinomas ENSG00000169047 ENSG00000196712 PMC5501956__F3 KEGG MAPK signaling pathway (KEGG ID: hs04010) ENSG00000087095 ENSG00000170458 ENSG00000130522 ENSG00000130159 ENSG00000175104 ENSG00000127191 ENSG00000111816 ENSG00000081189 ENSG00000196712 ENSG00000026103 PMC4745004__F8 Colorectal cancer characterization and therapeutic target prediction based on microRNA expression profile ENSG00000124102 ENSG00000111537 ENSG00000095739 ENSG00000100387 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000067900 ENSG00000205250 ENSG00000137801 PMC7864517__F2 In the absence of Hedgehog (HH) ligand (SHH, IHH, and DHH), the Patched 1 (PTCH) transmembrane receptor at the base of the primary cilium maintains inhibition of Smoothened (SMO) G protein coupled receptor (GPCR) signaling ENSG00000106571 ENSG00000166813 ENSG00000288335 ENSG00000164690 ENSG00000171791 ENSG00000128602 ENSG00000150630 PMC8901637__F6 Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased B2 adrenergic agonist ENSG00000110330 ENSG00000137673 ENSG00000163914 ENSG00000114268 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC4568905__F5 2-Hydroxy Acids in Plant Metabolism PMC8386020__F4 Antimetastatic Effects of Curcumin in Oral and Gastrointestinal Cancers ENSG00000203485 ENSG00000146648 PMC6031751__F8 CS negatively regulates IL-1B secretion in murine macrophages ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC7738619__F1 Summary of the epigenetic regulation of the GSC phenotype ENSG00000198901 ENSG00000084093 ENSG00000151376 ENSG00000117650 ENSG00000005483 ENSG00000004487 ENSG00000253352 ENSG00000122779 ENSG00000168610 ENSG00000082212 PMC9104610__F6 Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling ENSG00000105329 ENSG00000064989 ENSG00000091879 ENSG00000112715 ENSG00000154188 ENSG00000150630 PMC4932205__F4 Genes which are involved in the telomere maintenance and telomerase activity pathway ENSG00000149311 ENSG00000132604 ENSG00000079246 ENSG00000130826 ENSG00000104320 ENSG00000164362 ENSG00000291791 ENSG00000147601 ENSG00000128513 ENSG00000092330 PMC5477652__F1 Targeting the cyclin D–cyclin-dependent kinase (CDK)4/6–retinoblastoma pathway with selective CDK 4/6 inhibitors in hormone receptor-positive breast cancer: rationale, current status, and future directions ENSG00000169291 ENSG00000135446 ENSG00000198793 ENSG00000185591 ENSG00000105810 PMC3808847__F1 Kisspeptin and Neurokinin B Pathway Deficiencies and Resulting Phenotypes in Mice and Men ENSG00000170498 ENSG00000163501 PMC3822533__F3 Unfolded protein response in mammalian cells ENSG00000128272 ENSG00000127191 PMC7146376__F2 Location of CYP27B1 activity in the metabolic pathway of vitamin D (based on Jenkinson 2019 and Feldman et al ENSG00000111012 ENSG00000172893 ENSG00000019186 ENSG00000186104 ENSG00000135929 PMC4020326__F2 Glucogen‐like peptide‐1 and cancer ENSG00000140443 PMC7893032__F1 Cell death in head and neck cancer pathogenesis and treatment ENSG00000102871 ENSG00000168404 ENSG00000285379 PMC9170601__F3 Emerging roles of activating transcription factor (ATF) family members in tumourigenesis and immunity: Implications in cancer immunotherapy ENSG00000169136 ENSG00000170653 ENSG00000162772 ENSG00000123268 PMC8199938__F5 Therapeutic Attributes of Endocannabinoid System against Neuro-Inflammatory Autoimmune Disorders ENSG00000117480 ENSG00000196689 PMC7893032__F2 Cell death in head and neck cancer pathogenesis and treatment ENSG00000278718 ENSG00000162711 ENSG00000125538 ENSG00000189403 PMC7193099__F2 Hippo pathway in heart development and homeostasis ENSG00000160551 ENSG00000150457 ENSG00000131023 PMC7327153__F2 TLR10 and Its Unique Anti-Inflammatory Properties and Potential Use as a Target in Therapeutics ENSG00000174123 ENSG00000174125 ENSG00000125538 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC6389705__F1 Intrinsic and extrinsic pathways of neutrophil apoptosis ENSG00000102871 ENSG00000168040 PMC4268391__F1 RTK-PI3K-AKT signaling pathway ENSG00000198793 ENSG00000136997 ENSG00000140443 PMC9325865__F1 Cell death induction in Aspergillus fumigatus: accentuating drug toxicity through inhibition of the unfolded protein response (UPR) ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8905337__F1 Myostatin/Activin Receptor Ligands in Muscle and the Development Status of Attenuating Drugs ENSG00000170365 ENSG00000241186 ENSG00000135414 ENSG00000130283 ENSG00000266524 ENSG00000184344 PMC3018096__F1 Adapters in the organization of mast cell signaling ENSG00000033327 ENSG00000010810 ENSG00000086730 PMC9406569__F4 Cathepsin K: A Versatile Potential Biomarker and Therapeutic Target for Various Cancers ENSG00000198793 ENSG00000112561 ENSG00000175104 ENSG00000143387 PMC3149150__F2 Regulation of STEP phosphorylation ENSG00000010810 ENSG00000178568 PMC9406569__F6 Cathepsin K: A Versatile Potential Biomarker and Therapeutic Target for Various Cancers ENSG00000170458 ENSG00000135439 ENSG00000140968 ENSG00000172936 ENSG00000150455 ENSG00000168610 ENSG00000132341 ENSG00000143387 PMC5056850__F2 Signaling via PINCH: functions, binding partners and implications in human diseases ENSG00000071051 ENSG00000148484 PMC9406569__F5 Cathepsin K: A Versatile Potential Biomarker and Therapeutic Target for Various Cancers ENSG00000198793 ENSG00000143387 PMC3989668__F2 Ubiquitin-proteasome system maintains the balance between quiescence, self-renewal, and differentiation of HSCs.(A) The E3 ligases Itch, SCFFbxw7,CBL and SCFSkp2 maintain the quiescence of the HSC by targeting Notch, c-Myc, and STAT5, among others ENSG00000145604 ENSG00000134086 ENSG00000110395 ENSG00000144554 ENSG00000078747 ENSG00000162607 ENSG00000109670 PMC4156155__F1 INFLAMMATION AND LIPID SIGNALING IN THE ETIOLOGY OF INSULIN RESISTANCE ENSG00000291971 ENSG00000136869 PMC4030154__F2 Metals and cholesterol implicated in AB processing and neurotoxicity ENSG00000130164 ENSG00000119912 PMC3630242__F1 Leptin and adiponectin activate signaling components that integrate PI3K/Akt, RAS/MAPK, and pAMPK/mTor pathways ENSG00000157500 ENSG00000169047 ENSG00000177606 ENSG00000159346 ENSG00000138777 ENSG00000285070 ENSG00000132693 PMC3989668__F3 Ubiquitylation maintains the equilibrium between differentiation and transformation in adult stem cells ENSG00000078747 ENSG00000134982 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000109670 PMC7665057__F6 Predicted pathway and network of all the 11 miRNAs ENSG00000144366 ENSG00000153989 ENSG00000178537 ENSG00000078579 ENSG00000132326 ENSG00000169429 ENSG00000112715 ENSG00000285112 ENSG00000109787 PMC9039247__F2 Cellular Metabolism in the Formation of Neutrophil Extracellular Traps in Airway Diseases ENSG00000110218 ENSG00000005381 ENSG00000115419 PMC1716221__F1 Dominant role for glucose in B cell compensation of insulin resistance ENSG00000140992 ENSG00000171105 ENSG00000150907 PMC7763279__F2 Wingless and Int-1 (WNT) signaling pathways and their role during the osteochondrogenic transition of synthetic vascular smooth muscle cells (VSMC) ENSG00000139219 ENSG00000154342 ENSG00000281324 ENSG00000125398 ENSG00000169071 ENSG00000162337 ENSG00000157766 ENSG00000185483 ENSG00000168036 ENSG00000110693 PMC7055192__F3 Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies ENSG00000130164 ENSG00000160179 PMC3218875__F2 Noncanonical NFKB signalling ENSG00000104856 ENSG00000056558 ENSG00000111321 ENSG00000131323 ENSG00000127191 PMC8534120__F2 Sphingolipids in Hematopoiesis: Exploring Their Role in Lineage Commitment ENSG00000167769 ENSG00000285281 ENSG00000135587 ENSG00000143418 ENSG00000139624 ENSG00000198964 ENSG00000063176 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000100596 ENSG00000173599 ENSG00000292130 ENSG00000164023 ENSG00000188611 ENSG00000166224 ENSG00000078124 ENSG00000119537 ENSG00000168350 ENSG00000163082 PMC7763279__F3 Interplay of WNT and PPARG Signaling in Vascular Calcification ENSG00000281324 ENSG00000171720 ENSG00000162337 ENSG00000134982 ENSG00000120057 ENSG00000168036 PMC3902114__F1 Targeting inflammatory cytokines-androgen receptor (AR) signaling with ASC-J9® to better battle prostate cancer progression ENSG00000108691 ENSG00000121807 ENSG00000277943 PMC4516600__F4 A schematic pathway for one mechanisms of cisplatin-induced ototoxicity involves TRPV1 activation by cisplatin leads to NOX3-dependent generation of ROS to trigger STAT1 activation ENSG00000115415 ENSG00000074771 ENSG00000196689 PMC9433531__F4 Mobocertinib, a new irreversible tyrosine kinase inhibitor indicated for the treatment of non-small-cell lung cancer harboring EGFR exon 20 insertion mutations ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC5812366__F1 Major mechanisms of therapeutic resistance to androgen axis-targeting therapies in prostate cancer ENSG00000138798 ENSG00000198793 ENSG00000171791 ENSG00000122779 PMC7333666__F1 Simple overview of the Hippo signaling pathway and YAP ENSG00000186575 ENSG00000159216 ENSG00000197905 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000089225 ENSG00000178568 ENSG00000074219 PMC7002859__F1 Steroidogenesis pathway involved in testosterone synthesis from cholesterol in testicular Leydig cells ENSG00000203857 PMC4128657__F4 An Interferon Response Gene Signature Is Associated with the Therapeutic Response of Hepatitis C Patients ENSG00000135828 PMC4128657__F5 An Interferon Response Gene Signature Is Associated with the Therapeutic Response of Hepatitis C Patients ENSG00000213928 ENSG00000250361 ENSG00000187608 ENSG00000137275 ENSG00000177606 PMC4491880__F1 Deoxycytidine biosynthetic pathway ENSG00000161634 ENSG00000128951 ENSG00000254550 PMC8387860__F2 Senescence and senolytics in cardiovascular disease: Promise and potential pitfalls ENSG00000002330 ENSG00000291971 ENSG00000120868 PMC9203694__F6 Microrchidia CW-Type Zinc Finger 2, a Chromatin Modifier in a Spectrum of Peripheral Neuropathies ENSG00000131473 ENSG00000133422 ENSG00000026103 PMC9203694__F5 Microrchidia CW-Type Zinc Finger 2, a Chromatin Modifier in a Spectrum of Peripheral Neuropathies ENSG00000143799 ENSG00000149311 ENSG00000149269 ENSG00000133422 PMC5797330__F3 Endothelial Progenitor Cells for the Vascularization of Engineered Tissues ENSG00000070831 ENSG00000163914 ENSG00000173599 ENSG00000172889 ENSG00000168036 PMC8346997__F2 GPR39 in Neurovascular Homeostasis and Disease ENSG00000163914 ENSG00000183840 PMC12240974__F1 BAF60c in skeletal muscle glucose metabolism and regeneration ENSG00000050165 ENSG00000155792 ENSG00000100625 PMC4824131__F1 NRAS mutant skin cell lines mutations in the TLR3 Cascade pathway ENSG00000100906 ENSG00000134070 ENSG00000100784 ENSG00000135341 ENSG00000114738 PMC7477231__F8 Exosome-transferred LINC01559 promotes the progression of gastric cancer via PI3K/AKT signaling pathway ENSG00000178860 ENSG00000151376 ENSG00000145321 PMC9565660__F1 Personalized quantitative models of NAD metabolism in hepatocellular carcinoma identify a subgroup with poor prognosis ENSG00000166278 PMC7333666__F3 Role of YAP in the cytoplasm and nucleus regarding central nervous system disease ENSG00000120833 ENSG00000186575 ENSG00000168610 ENSG00000178568 ENSG00000074219 PMC8943788__F6 rs2671655 single nucleotide polymorphism modulates the risk for gastric cancer in Helicobacter pylori–infected individuals: a genome-wide association study in the Korean population ENSG00000198740 ENSG00000145321 ENSG00000121067 PMC6830101__F12 Graphical summary of perceived crosstalk of BMP2-mediated signaling and the NO pathway ENSG00000170365 PMC10341762__F1 One-carbon metabolism ENSG00000228716 ENSG00000002330 ENSG00000100714 ENSG00000124275 PMC6651320__F1 Schematic representation of MVA pathway ENSG00000116133 ENSG00000172893 ENSG00000113161 ENSG00000104549 PMC9069407__F3 Generation of PD-L1 and PD-L2 in cancer cells: From nuclear chromatin reorganization to extracellular presentation ENSG00000182481 ENSG00000091317 ENSG00000118007 ENSG00000101972 ENSG00000111537 ENSG00000183723 ENSG00000121067 ENSG00000168610 ENSG00000147697 PMC7565951__F2 Roles of TRIM proteins in pattern recognition receptors (PRRs)-mediated immune signaling pathway ENSG00000135655 ENSG00000166326 ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000121060 ENSG00000276561 PMC7235403__F7 Lysosome pathway in DEX-treated sarcoid AMs ENSG00000198951 ENSG00000107798 ENSG00000181523 ENSG00000134575 ENSG00000150967 ENSG00000038002 ENSG00000169919 ENSG00000110719 ENSG00000143387 ENSG00000291507 ENSG00000159720 ENSG00000166501 ENSG00000189067 PMC7235403__F6 Effect of DEX on metabolic pathways in sarcoid AMs ENSG00000169021 ENSG00000164904 ENSG00000073578 ENSG00000184983 ENSG00000166260 ENSG00000087008 ENSG00000126267 ENSG00000105953 ENSG00000010256 ENSG00000120437 ENSG00000101365 ENSG00000233954 ENSG00000074800 ENSG00000100412 ENSG00000131480 ENSG00000122971 ENSG00000146701 ENSG00000159399 PMC4724610__F1 Systematic representation of microRNA biogenesis, deregulation and function ENSG00000128191 ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC12119277__F3 Mechanisms by which mediators of inflammation resolution regulate neutrophil apoptosis and survival ENSG00000002330 ENSG00000170775 ENSG00000133067 ENSG00000171049 ENSG00000120868 ENSG00000005381 PMC1851054__F6 SFK-dependent PI3K-ERK2 and phospholipase CG-JNK1 pathways ENSG00000117091 ENSG00000149269 ENSG00000204520 ENSG00000141968 PMC12119277__F2 Neutrophil apoptosis ENSG00000120868 PMC3395736__F1 Glycolytic pathway and its metabolic interconnection with the pentose-phosphate pathway PMC6412216__F5 Mediation of the maturation and activation of BMDCs during Mycobacterium bovis infection by the cGAS pathway ENSG00000183735 ENSG00000164430 ENSG00000142166 PMC3639292__F3 Metabolic rewiring in melanoma engages more carbon than just glucose ENSG00000092621 ENSG00000115419 ENSG00000026103 ENSG00000167701 PMC4628764__F1 Heme biosynthetic pathway in erythroid cells ENSG00000123643 ENSG00000205221 ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000158578 ENSG00000256269 ENSG00000188690 ENSG00000115657 ENSG00000144659 ENSG00000135776 ENSG00000284936 ENSG00000115107 PMC5406702__F3 EGFR family members regulate autophagy affecting cancer cell survival and death ENSG00000177169 ENSG00000110497 ENSG00000198382 ENSG00000126775 ENSG00000104341 ENSG00000145782 ENSG00000146648 PMC5777650__F6 Parallel PI3K, AKT and mTOR inhibition is required to control feedback loops that limit tumor therapy ENSG00000198793 ENSG00000164327 ENSG00000087842 PMC2999286__F1 The involvement of the Unfolded Protein Response (UPR) signaling in lipid metabolism ENSG00000042832 ENSG00000144895 ENSG00000100219 PMC5070725__F1 Schematic model of metabolic regulation by S6K1 in two ways ENSG00000169884 PMC6925592__F2 Smad7 Restricts DC Responsiveness to TGFB and Their Ability to Induce Tregs ENSG00000104899 ENSG00000133937 ENSG00000134363 ENSG00000124766 ENSG00000049768 ENSG00000123999 ENSG00000141232 ENSG00000159216 ENSG00000096395 ENSG00000095739 ENSG00000135409 ENSG00000136997 ENSG00000125968 ENSG00000134531 PMC8510449__F6 Recent Advances in Understanding the Mechanisms of Elemene in Reversing Drug Resistance in Tumor Cells: A Review ENSG00000012061 ENSG00000002330 ENSG00000132964 ENSG00000168610 PMC8510449__F5 Recent Advances in Understanding the Mechanisms of Elemene in Reversing Drug Resistance in Tumor Cells: A Review ENSG00000169554 ENSG00000272398 ENSG00000026508 ENSG00000146648 PMC8306430__F3 Early Functional Impairment in Experimental Glaucoma Is Accompanied by Disruption of the GABAergic System and Inceptive Neuroinflammation ENSG00000145864 ENSG00000161681 ENSG00000173369 ENSG00000138642 ENSG00000079432 ENSG00000205220 ENSG00000182256 PMC5220041__F5 Thyroid cancer-related signaling pathway relational graph ENSG00000157764 ENSG00000198793 ENSG00000100985 PMC7105005__F2 CGAS/STING-signaling through Post-Translational Modifications (PTMs) ENSG00000177169 ENSG00000112343 ENSG00000119401 ENSG00000159461 ENSG00000137699 ENSG00000186480 ENSG00000169871 ENSG00000184979 ENSG00000090432 ENSG00000163904 ENSG00000183735 ENSG00000136878 ENSG00000164430 ENSG00000138468 ENSG00000138942 ENSG00000173456 PMC8510449__F7 Recent Advances in Understanding the Mechanisms of Elemene in Reversing Drug Resistance in Tumor Cells: A Review ENSG00000134057 PMC3302314__F2 Left half, signaling via IPS-1 following dsRNA/ssRNA recognition by RIG-I and MDA5 ENSG00000162711 ENSG00000102871 ENSG00000125538 ENSG00000131323 ENSG00000168040 ENSG00000276561 PMC3302314__F1 Signaling cascade following TLR2/TLR4, TLR7/TLR8, and TLR3 activation with envelope glycoprotein, ssRNA, and dsRNA, respectively ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC6550017__F5 GLI proteins are regulated by PKA ENSG00000143147 ENSG00000147256 ENSG00000128602 PMC11004261__F5 Revolutionizing pediatric neuroblastoma treatment: unraveling new molecular targets for precision interventions ENSG00000291971 ENSG00000135446 ENSG00000198793 ENSG00000177606 ENSG00000111186 ENSG00000171791 ENSG00000168610 ENSG00000164305 PMC2925066__F1 Major Apoptotic pathways ENSG00000120868 ENSG00000168040 ENSG00000115317 ENSG00000026103 PMC6550017__F1 HH signaling ENSG00000128602 PMC11004261__F4 Revolutionizing pediatric neuroblastoma treatment: unraveling new molecular targets for precision interventions PMC6824835__F2 AKAP5 and AKAP12 in modulating oxidative stress in cardiac cells ENSG00000105329 PMC11004261__F3 Revolutionizing pediatric neuroblastoma treatment: unraveling new molecular targets for precision interventions PMC9453300__F3 Emerging role of different DNA methyltransferases in the pathogenesis of cancer ENSG00000124102 ENSG00000002330 PMC11994733__F1 Suitable concentrations of brassinolide application enhances growth performance and saikosaponin biosynthesis by transcriptional activation of triterpenoid pathway genes in Bupleurum chinense DC ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC4977886__F4 Differentially expressed proteins regulated cellular processes/diseases and hypothetical depiction of BPA action ENSG00000117118 PMC2720436__F1 Hippo pathway, a vital growth regulator of cell proliferation and apoptosis was initially identified by mosaic screens in Drosophila melanogaster (,) ENSG00000110330 ENSG00000089685 ENSG00000131023 PMC8332859__F8 CR13626: a novel oral brain penetrant tyrosine kinase inhibitor that reduces tumor growth and prolongs survival in a mouse model of glioblastoma ENSG00000133116 ENSG00000010810 PMC3223252__F7 A refined model shows MEHP-decreased TIMP2 expression in Sertoli cells is mediated by the inactivation of CEBPA and the activation of MYC and is dependent upon the FSH-stimulated cAMP signaling pathway ENSG00000245848 ENSG00000087245 ENSG00000136997 PMC3897272__F1 Eicosanoid biosynthetic pathway ENSG00000166278 ENSG00000146648 PMC11994733__F6 Expression of key genes in the saikosaponin biosynthesis pathway in B ENSG00000143815 ENSG00000197429 ENSG00000102239 PMC5462947__F4 Metabolic traits of KF-JG30-18 (A) and DA052 (B) as derived from the genetic potential of RH2 MAG 17b and RH1 MAG20 ENSG00000121897 ENSG00000122966 ENSG00000172005 PMC4038253__F1 Simplified scheme of the N-glycosylation pathway ENSG00000101901 ENSG00000168282 ENSG00000119523 ENSG00000139133 ENSG00000033011 ENSG00000172269 ENSG00000163933 ENSG00000088035 ENSG00000214160 ENSG00000128268 ENSG00000182858 PMC8123211__F3 PARP Enzyme Family and the Hallmarks of Cancer Part 2: Hallmarks Related to Cancer Host Interactions ENSG00000143799 ENSG00000108691 ENSG00000107562 ENSG00000291971 ENSG00000291803 PMC8123211__F2 PARP Enzyme Family and the Hallmarks of Cancer Part 2: Hallmarks Related to Cancer Host Interactions ENSG00000143799 ENSG00000126016 ENSG00000118518 ENSG00000281324 ENSG00000162337 ENSG00000121481 ENSG00000026508 ENSG00000041880 ENSG00000178685 PMC7062835__F1 Molecular network identified using the “Interaction search” algorithm in KeyMolnet ENSG00000084764 ENSG00000125814 ENSG00000078369 ENSG00000153823 ENSG00000134982 ENSG00000136997 ENSG00000121905 ENSG00000163631 PMC6276090__F4 Signaling pathways in osteoclasts involving V-ATPases ENSG00000182578 ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000175104 PMC6627782__F3 mTOR signaling in spermatozoa from older men ENSG00000155792 ENSG00000204673 ENSG00000108443 ENSG00000167965 PMC9659959__F1 Nucleic acid-sensing toll-like receptors: Important players in Sjögren’s syndrome ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000131323 ENSG00000110057 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC6627782__F2 Network of the sperm proteins differentially associated with male age ENSG00000002330 ENSG00000067057 ENSG00000138772 ENSG00000198793 ENSG00000134308 ENSG00000100345 ENSG00000169710 ENSG00000170606 ENSG00000108443 ENSG00000120885 ENSG00000164305 ENSG00000181786 ENSG00000135624 ENSG00000197956 ENSG00000117020 ENSG00000185386 ENSG00000126803 ENSG00000204673 ENSG00000171053 ENSG00000188130 ENSG00000100304 PMC5564615__F7 Estrogen-activated MDM2 disrupts mammary tissue architecture through a p53-independent pathway ENSG00000185591 PMC2995824__F1 Regulation of muscle protein synthesis ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000186654 PMC3786361__F1 Epidermal growth factor receptor family and targeted agents ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000146648 PMC9597983__F2 Concanavalin A as a promising lectin-based anti-cancer agent: the molecular mechanisms and therapeutic potential ENSG00000171105 ENSG00000002330 ENSG00000188613 ENSG00000123374 ENSG00000146648 ENSG00000026103 ENSG00000126246 PMC3829478__F9 Wnt3a binds to Fz7 and cross-activate the IGF-1-PI3k-Akt pathway inducing initial axonal outgrowth and neuronal polarization ENSG00000154342 ENSG00000277641 ENSG00000155760 ENSG00000140443 PMC4772995__F2 Whole Transcriptome Analysis (RNA Sequencing) of Peripheral Blood Mononuclear Cells of Vitiligo Patients ENSG00000074964 ENSG00000064490 ENSG00000185340 ENSG00000105612 ENSG00000125912 ENSG00000118363 ENSG00000089127 ENSG00000274779 ENSG00000276051 ENSG00000175550 PMC22365__F5 Evolutionary conservation of the DNA damage and the replication checkpoints ENSG00000149311 ENSG00000175054 ENSG00000163624 PMC7844014__F6 Network of interactions significantly enriched for genes displaying altered methylation patterns following treatment with valeric acid ENSG00000094631 ENSG00000072571 ENSG00000182400 ENSG00000122068 ENSG00000274891 ENSG00000153914 ENSG00000143622 ENSG00000130803 ENSG00000100442 ENSG00000231377 ENSG00000145782 ENSG00000155363 PMC6497933__F6 Summary of the DEPs involved in central carbon metabolism and fatty acids synthesis ENSG00000122966 ENSG00000172005 ENSG00000111816 PMC2843167__F7 Summary of the findings presented here ENSG00000132646 ENSG00000196591 PMC4223335__F10 Concerted regulation of NFATc3 by electrical activity and NGF in sensory neurons PMC5831770__F1 Sonic hedgehog signaling pathway ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC6003838__F2 The spatio-temporal cell dynamics of the G-protein/Pth11 and cAMP-signaling pathway during surface sensing and appressorium morphogenesis ENSG00000090104 PMC4090390__F2 Metabolic fluxes, NLRP3 and IL-1B ENSG00000162711 ENSG00000121351 ENSG00000136869 PMC4669123__F1 Mammalian “Obesogen” Tributyltin Targets Hepatic Triglyceride Accumulation and the Transcriptional Regulation of Lipid Metabolism in the Liver and Brain of Zebrafish ENSG00000161533 ENSG00000169710 ENSG00000062282 PMC4090390__F1 Pathogenesis of T2D: adipose tissue, the pancreas, NLRP3 and T2D ENSG00000121351 ENSG00000125538 ENSG00000169047 PMC4957946__F1 Differentiating mTOR Inhibitors in Renal Cell Carcinoma ENSG00000134086 ENSG00000138798 ENSG00000198793 ENSG00000284161 ENSG00000164327 ENSG00000167965 ENSG00000146648 ENSG00000140443 PMC5649368__F3 Nuclear receptors outside the nucleus: extranuclear signalling by steroid receptors ENSG00000291971 ENSG00000146648 ENSG00000026103 PMC5649368__F1 Nuclear receptors outside the nucleus: extranuclear signalling by steroid receptors ENSG00000145321 ENSG00000185591 PMC4824563__F3 Network analysis ENSG00000023445 ENSG00000145632 ENSG00000071575 ENSG00000169908 ENSG00000147649 ENSG00000117228 ENSG00000128951 ENSG00000143878 ENSG00000232326 ENSG00000221869 ENSG00000169242 ENSG00000125347 ENSG00000038382 ENSG00000160224 ENSG00000140455 ENSG00000196792 ENSG00000143322 ENSG00000028137 ENSG00000125968 ENSG00000123983 PMC6992624__F3 An integrated computational and experimental study to investigate Staphylococcus aureus metabolism ENSG00000144063 ENSG00000124479 ENSG00000159224 ENSG00000065833 ENSG00000197713 ENSG00000173599 ENSG00000172005 ENSG00000096088 ENSG00000082212 ENSG00000062485 PMC9319476__F2 Transporter Regulation in Critical Protective Barriers: Focus on Brain and Placenta ENSG00000134982 ENSG00000168036 PMC9580404__F3 Regulatory role of KCa3.1 in immune cell function and its emerging association with rheumatoid arthritis ENSG00000084093 ENSG00000105639 ENSG00000115594 PMC8585775__F7 Proteomic Phenotyping of Stimulated Müller Cells Uncovers Profound Pro-Inflammatory Signaling and Antigen-Presenting Capacity ENSG00000111537 PMC5572303__F5 Proteomic Analysis of Normal and Cancer Cervical Cell Lines Reveals Deregulation of Cytoskeleton-associated Proteins ENSG00000172380 ENSG00000138443 ENSG00000138798 ENSG00000181104 ENSG00000089159 PMC3413225__F7 Model describing the mechanisms of quercetin-induced cholesterol efflux in macrophages ENSG00000145321 ENSG00000185591 PMC3570300__F5 Ingenuity Pathway Analysis of proteins induced by DNP.A, overview of 15 specific functional networks, each of which contains 11 or more “focus” proteins (proteins that were significantly up- or down-regulated) ENSG00000087245 ENSG00000182568 ENSG00000114416 ENSG00000091409 ENSG00000171824 ENSG00000171791 ENSG00000166278 ENSG00000168610 ENSG00000089159 ENSG00000116984 ENSG00000166136 ENSG00000109854 ENSG00000011422 ENSG00000078900 ENSG00000285482 ENSG00000146648 PMC7697665__F2 Role of RNF11 in the transforming growth factor beta (TGFB) signaling pathway ENSG00000123091 ENSG00000078747 ENSG00000198742 ENSG00000123124 PMC3914023__F3 A model of the EZH2 functional switch from a polycomb repressor to a transcriptional activator in castration-resistant prostate cancer ENSG00000084093 ENSG00000074266 ENSG00000178691 PMC6829404__F8 Leptin-induced EMT via Src and FAK signaling pathways ENSG00000291971 ENSG00000138798 ENSG00000168036 ENSG00000146648 PMC3527145__F1 The left-right asymmetry pathway ENSG00000143768 ENSG00000156574 ENSG00000164093 PMC6539494__F4 Single-Cell RNA-Sequencing Identifies Activation of TP53 and STAT1 Pathways in Human T Lymphocyte Subpopulations in Response to Ex Vivo Radiation Exposure ENSG00000136997 PMC3690365__F2 Pathways that control levels of macroautophagy ENSG00000126775 ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC6708273__F6 Contribution of Oxidative Stress and Impaired Biogenesis of Pancreatic Beta-Cells to Type 2 Diabetes ENSG00000198793 ENSG00000136997 ENSG00000182759 PMC5209821__F4 Working hypothesis of the mechanism through which different miRNAs regulate the PTEN pathway, PI3K/AKT and STAT signalling in sperm ENSG00000104812 ENSG00000198793 ENSG00000111713 ENSG00000136997 ENSG00000137193 ENSG00000171791 ENSG00000164305 PMC8616451__F1 Therapeutic Potential of MRGPRX2 Inhibitors on Mast Cells ENSG00000183695 ENSG00000137033 ENSG00000172936 PMC9369061__F1 JAK/STAT Pathway and Its Selective Inhibition in the Treatment of Atopic Dermatitis: A Systematic Review ENSG00000105397 ENSG00000115415 ENSG00000204671 ENSG00000113520 ENSG00000145777 ENSG00000105639 ENSG00000168610 ENSG00000113525 PMC8497618__F8 Proposed model of how Enpp4/S1pr5 controls pronephros patterning ENSG00000162552 ENSG00000001561 ENSG00000180739 PMC5564786__F6 MiR-650 represses high-risk non-metastatic colorectal cancer progression via inhibition of AKT2/GSK3B/E-cadherin pathway ENSG00000168036 PMC6115855__F7 Anti-cancer mechanism of the PEC treatment in both AGS and MKN28 cells ENSG00000198793 PMC11884773__F1 Coptisine ameliorates colitis in mice by modulating cPLA2/TRPM8/CGRP-1 signaling pathways and strengthening intestinal barrier function ENSG00000104321 ENSG00000196689 PMC7542154__F3 Immunoregulation of PD-L1/PD-1 in GBC ENSG00000065361 ENSG00000198793 ENSG00000146648 PMC5711031__F10 Interleukin-1beta (IL-1B)-induced Notch ligand Jagged1 suppresses mitogenic action of IL-1B on human dystrophic myogenic cells ENSG00000074181 ENSG00000125538 ENSG00000108342 ENSG00000164400 PMC8452392__F7 Exploring the Molecular Mechanism of Liuwei Dihuang Pills for Treating Diabetic Nephropathy by Combined Network Pharmacology and Molecular Docking ENSG00000087245 ENSG00000108582 ENSG00000135446 ENSG00000137193 ENSG00000007908 PMC4802778__F2 Role of sortilin in EV biogenesis PMC3608394__F6 Enriched pathways and GO functional annotations are: (a) ErbB signaling pathway: p=9.10e-13; Signal transduction p=2.33e-07 ENSG00000171105 ENSG00000148400 ENSG00000291971 ENSG00000100060 ENSG00000091879 ENSG00000137801 ENSG00000160691 ENSG00000143801 ENSG00000178188 ENSG00000074181 ENSG00000101346 ENSG00000146648 ENSG00000101213 ENSG00000100603 PMC8624197__F3 Bioconversion of Lignocellulosic Biomass into Value Added Products under Anaerobic Conditions: Insight into Proteomic Studies PMC3608394__F5 Subnetworks identified from TCGA ovarian cancer gene expression data set ENSG00000012048 ENSG00000142192 ENSG00000005339 ENSG00000291971 ENSG00000136997 ENSG00000087586 ENSG00000051180 ENSG00000139687 ENSG00000106003 PMC8548690__F6 Can the Cytokine Profile According to ABO Blood Groups Be Related to Worse Outcome in COVID-19 Patients? Yes, They Can ENSG00000130234 ENSG00000112115 PMC3608394__F7 Enriched pathways and GO functional annotations are: (a) NFKB signaling pathway p=7.03e-05 ENSG00000141232 ENSG00000104365 ENSG00000109332 ENSG00000160973 ENSG00000282905 ENSG00000188191 ENSG00000005339 ENSG00000148660 ENSG00000172216 ENSG00000109320 PMC8539121__F1 In Vitro Analysis of Deoxynivalenol Influence on Steroidogenesis in Prostate PMC11010822__F7 MTA1/mTOR pathway in prostate cancer ENSG00000198793 PMC2409614__F3 Development of tamoxifen (TAM)-resistant breast cancer and the changing role of oestradiol (E2) in the life and death of ER-positive cancer cells ENSG00000168040 ENSG00000146648 ENSG00000026103 PMC2601665__F1 Hh-Gli pathway and the Gli code in tissue patterning and stem-cell lineages ENSG00000078747 ENSG00000143839 ENSG00000133961 ENSG00000128602 PMC3148240__F1 Simulating EGFR-ERK Signaling Control by Scaffold Proteins KSR and MP1 Reveals Differential Ligand-Sensitivity Co-Regulated by Cbl-CIN85 and Endophilin ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC8857760__F3 Oncopreventive and oncotherapeutic potential of licorice triterpenoid compound glycyrrhizin and its derivatives: Molecular insights ENSG00000120868 ENSG00000026103 PMC8857760__F2 Oncopreventive and oncotherapeutic potential of licorice triterpenoid compound glycyrrhizin and its derivatives: Molecular insights ENSG00000187554 ENSG00000189403 ENSG00000172936 PMC3517080__F5 Putative Altered Signaling Events occurring upon treatment of GSI ENSG00000132646 ENSG00000100345 ENSG00000131095 ENSG00000170515 PMC4657516__F5 Antioxidants in Translational Medicine ENSG00000178573 ENSG00000079999 PMC9289522__F1 Distinct Cell-specific Roles of NOX2 and MyD88 in Epileptogenesis ENSG00000162711 ENSG00000172936 ENSG00000136869 PMC8815087__F4 Phosphodiesterase 1 (PDE1) regulated cAMP and cGMP signaling pathway in cancer and neurological disorders ENSG00000123360 ENSG00000253506 ENSG00000173786 ENSG00000276043 PMC9142082__F1 Double-Stranded Break Repair in Mammalian Cells and Precise Genome Editing ENSG00000169621 ENSG00000039650 ENSG00000165392 ENSG00000310560 PMC4155268__F5 The cytoprotective signaling of EPCR-APC ENSG00000134982 PMC11674240__F2 TRIM proteins in the signaling pathways ENSG00000154370 ENSG00000132109 ENSG00000213186 ENSG00000166326 ENSG00000106785 ENSG00000134982 ENSG00000102871 ENSG00000119401 ENSG00000137699 ENSG00000168036 ENSG00000168040 ENSG00000141569 ENSG00000183718 ENSG00000132481 ENSG00000122779 ENSG00000162722 ENSG00000121060 ENSG00000221926 ENSG00000130726 PMC3976840__F2 FASN related metabolic and signal transduction pathways ENSG00000131473 ENSG00000169710 PMC8826578__F3 Review of LINC00707: A Novel LncRNA and Promising Biomarker for Human Diseases ENSG00000111665 ENSG00000070831 ENSG00000058091 PMC8579148__F4 Cooperation of cell adhesion and autophagy in the brain: Functional roles in development and neurodegenerative disease ENSG00000177169 ENSG00000291971 ENSG00000138798 ENSG00000057663 PMC8618147__F6 Unravelling the Immunomodulatory Effects of Viral Ion Channels, towards the Treatment of Disease ENSG00000162711 ENSG00000213928 ENSG00000115415 ENSG00000130234 ENSG00000125538 ENSG00000112561 ENSG00000131323 PMC8231629__F3 Impact of Hydrogen Peroxide on Protein Synthesis in Yeast ENSG00000144895 PMC4104069__F2 Pathways to Tumorigenesis and Persistent Infection ENSG00000172936 ENSG00000136869 ENSG00000184216 ENSG00000164342 PMC2668926__F1 EGFR Signaling Pathway ENSG00000135446 ENSG00000105810 PMC8831132__F1 NAD+ in COVID-19 and viral infections ENSG00000143799 ENSG00000105835 ENSG00000123572 PMC8665869__F5 Ginsenoside Rg1 Inhibits Microglia Pyroptosis Induced by Lipopolysaccharide Through Regulating STAT3 Signaling ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000168610 PMC7813757__F1 Mechanism underlying the role of TLRs in tumor immunity ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000136869 PMC5349223__F6 Regulation of Posttranslational Modifications of HMGB1 During Immune Responses ENSG00000189403 ENSG00000172936 ENSG00000130159 ENSG00000150455 ENSG00000175104 PMC8929128__F1 Impact of Vitamin D Supplementation on Inflammatory Markers’ Levels in Obese Patients ENSG00000158234 ENSG00000135929 PMC2875058__F2 Several disease pathways involved in AD pathogenesis ENSG00000185933 ENSG00000203710 ENSG00000120885 ENSG00000073921 ENSG00000137642 PMC5493925__F3 Regulation of the zebra finch RLR pathway ENSG00000184995 ENSG00000083799 ENSG00000168040 ENSG00000127191 PMC8174116__F5 Bioinformatics Analysis of a Prognostic miRNA Signature and Potential Key Genes in Pancreatic Cancer ENSG00000109452 ENSG00000185070 ENSG00000164283 ENSG00000159388 ENSG00000170500 ENSG00000151693 ENSG00000168615 ENSG00000185010 ENSG00000136231 ENSG00000204262 ENSG00000137807 ENSG00000109084 ENSG00000170927 ENSG00000133958 ENSG00000157227 ENSG00000038427 ENSG00000180263 ENSG00000170786 ENSG00000170537 ENSG00000163492 ENSG00000165434 ENSG00000112394 ENSG00000136155 ENSG00000205502 ENSG00000108821 ENSG00000118257 ENSG00000124374 ENSG00000169851 ENSG00000182010 ENSG00000136379 ENSG00000115648 ENSG00000164946 ENSG00000003989 ENSG00000111799 ENSG00000070526 ENSG00000115361 ENSG00000147576 ENSG00000151617 ENSG00000185567 ENSG00000115461 ENSG00000143954 ENSG00000132031 ENSG00000119508 ENSG00000104112 ENSG00000117707 ENSG00000173391 ENSG00000185518 ENSG00000116194 ENSG00000072657 ENSG00000181019 ENSG00000186340 ENSG00000079689 ENSG00000136153 ENSG00000146038 ENSG00000164379 ENSG00000135423 ENSG00000164694 ENSG00000115221 ENSG00000164171 ENSG00000014914 ENSG00000116106 ENSG00000121351 ENSG00000094755 ENSG00000291748 ENSG00000164756 ENSG00000100985 ENSG00000055732 ENSG00000156535 PMC7831039__F1 mut-p53 alters the communication of tumor cells with their microenvironment ENSG00000169245 ENSG00000065357 ENSG00000183735 ENSG00000157500 PMC10407612__F8 Ghrelin in promotion of ADMSCs cardiomyocyte differentiation ENSG00000285109 ENSG00000168036 ENSG00000106483 PMC11810460__F3 Schematic representation of cellular targets of HDACi and targeted BRAF mutant therapy concepts of relevance for cell death mechanisms ENSG00000157764 ENSG00000151012 ENSG00000198793 ENSG00000154059 PMC4866972__F1 Intrinsic and extrinsic pathways of apoptosis ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC4866972__F3 Principal cell death pathways involved in intervertebral disc (IVD) degeneration ENSG00000198793 ENSG00000168040 PMC6710443__F10 Schematic diagram of the mechanisms about the role of HDAC3/NF-kappaB pathway in pathogenesis and exercise therapy of OA ENSG00000154736 ENSG00000171720 ENSG00000125538 PMC3303591__F1 Stimulation of PI-3K/Akt signaling pathway after activation of IR/IGF-1R mediates insulin neuroprotection against damaging conditions PMC2529154__F4 Four components to yield MDP chromophore ENSG00000039537 ENSG00000124479 ENSG00000166278 PMC6378136__F2 Endosomal sorting and trafficking, the retromer complex and neurodegeneration ENSG00000142192 ENSG00000069329 PMC5572632__F2 Salvianolic acid B protects against diabetic atherosclerosis via the Nrf2 signalling pathway ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC5483877__F1 Strategies of effective targeting of hepatocyte growth factor (HGF)/c-Met signaling for the prevention of hepatocellular carcinoma (HCC) ENSG00000124102 ENSG00000019991 PMC8741925__F7 Mechanical stress dampens the CR, resulting in the degeneration of IVDs through the Rho/ROCK pathway ENSG00000149968 ENSG00000100985 ENSG00000158859 PMC3952039__F1 To Bud or not to Bud: The RET perspective in CAKUT ENSG00000291971 PMC3063605__F1 Simplified cartoon of PRR signaling in epithelial cells showing only the canonical pathway of NFKB activation and some of the key receptors, adaptors, and kinases involved ENSG00000174125 ENSG00000112977 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 PMC5572632__F1 NFKB signalling pathway is involved in the diabetic atherosclerosis ENSG00000101255 ENSG00000169047 ENSG00000173599 PMC3271045__F4 Schematic summary of striatal gene expression changes in response to SNCA overexpression ENSG00000116133 ENSG00000164326 ENSG00000081189 ENSG00000149295 PMC4465570__F3 Genome-wide association study points to multiple loci predicting antidepressant treatment outcome in depression ENSG00000170961 ENSG00000135218 ENSG00000105854 ENSG00000146072 ENSG00000120915 ENSG00000101057 ENSG00000198626 ENSG00000105426 PMC10454149__F1 MiRNA-146a—A Key Player in Immunity and Diseases ENSG00000174125 ENSG00000170458 ENSG00000187554 ENSG00000134070 ENSG00000172936 ENSG00000175104 PMC8193053__F9 Ligustrazine Alleviate Acute Lung Injury Through Suppressing Pyroptosis and Apoptosis of Alveolar Macrophages ENSG00000162711 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000168040 ENSG00000175104 ENSG00000184216 PMC6770479__F1 Molecular mechanisms involved in inflammasome activation ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000091592 ENSG00000091106 PMC6770479__F3 Chemotherapy-induced apoptosis and pyroptosis in cancer cell ENSG00000168040 PMC3514612__F7 Synthesis of nitric oxide and transduction cascades ENSG00000198576 PMC10454149__F3 MiRNA-146a—A Key Player in Immunity and Diseases ENSG00000168884 ENSG00000104856 ENSG00000104365 ENSG00000100906 ENSG00000109320 ENSG00000173039 ENSG00000162924 ENSG00000213341 PMC3533650__F10 Regulation of the FOXO3a survival, and glycolysis pathways under hypoxia in Spalax ENSG00000198793 ENSG00000136997 ENSG00000159399 PMC10454149__F2 MiRNA-146a—A Key Player in Immunity and Diseases ENSG00000143799 ENSG00000102871 ENSG00000135253 ENSG00000111321 ENSG00000150455 ENSG00000010671 ENSG00000095585 ENSG00000149311 ENSG00000226275 ENSG00000213658 ENSG00000135960 ENSG00000170458 ENSG00000186716 ENSG00000144118 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000121060 PMC6904929__F2 MicroRNA Mediated Regulation of Immunity against Gram-Negative Bacteria ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC9038741__F5 Metabolic reconstruction of Angelarchaeales-1 genome ENSG00000122966 ENSG00000172005 PMC6478758__F3 Pervasive regulation of TLR signaling pathway by miR-146a/b family and miR-125a~99b~let-7e cluster ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000168610 ENSG00000184216 PMC8870611__F2 Prognostic and Predictive Molecular Markers in Cholangiocarcinoma ENSG00000019991 ENSG00000066468 ENSG00000138798 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC5030800__F10 The regulation of lysosomal biogenesis and autophagy by cathepsin B in response to infection with F ENSG00000177169 ENSG00000198793 ENSG00000112561 PMC4698384__F3 Downstream gene targets of predicted cytokine and transcriptional regulators ENSG00000169047 ENSG00000102575 ENSG00000143226 ENSG00000178726 ENSG00000064666 ENSG00000274619 ENSG00000245848 ENSG00000066336 ENSG00000167779 ENSG00000125538 ENSG00000111341 ENSG00000057252 ENSG00000148346 ENSG00000142227 ENSG00000154736 ENSG00000100906 ENSG00000148400 ENSG00000105516 ENSG00000196954 ENSG00000168610 ENSG00000081189 ENSG00000089225 ENSG00000109814 ENSG00000019582 ENSG00000260314 ENSG00000111537 ENSG00000133110 ENSG00000163131 ENSG00000028137 ENSG00000187955 PMC7056466__F1 Hydroxytyrosol (HT) and its main biological actions ENSG00000168610 PMC4336643__F8 Proposed signaling pathway ENSG00000177606 ENSG00000132478 PMC3436686__F6 Ensemble representation of EGF signalling network ENSG00000136158 ENSG00000291971 ENSG00000138798 ENSG00000115904 ENSG00000171791 ENSG00000169032 ENSG00000089159 ENSG00000160691 ENSG00000179295 ENSG00000110395 ENSG00000067606 ENSG00000177606 ENSG00000106070 ENSG00000146648 ENSG00000184304 PMC3186711__F8 A model of the role of TLR4 signaling pathways in regulating TNFA expression ENSG00000172005 ENSG00000172936 ENSG00000136869 PMC4046345__F2 dsRNA-Activation of TLR3 and RLR Signaling: Gene Induction-Dependent and Independent Effects ENSG00000094631 ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC5601671__F6 The apoptotic signaling pathway of microRNA-155 in splenic lymphocytes ENSG00000028137 PMC11755087__F2 Schematic diagram showing insulin pathway in C ENSG00000118515 PMC4985526__F1 Molecular signature of pancreatic adenocarcinoma: an insight from genotype to phenotype and challenges for targeted therapy ENSG00000124102 ENSG00000198793 ENSG00000146648 PMC4044299__F4 TG2-mediated adhesion/signaling at the cell surface ENSG00000291971 ENSG00000168036 PMC4655955__F1 IPA prediction of the interactive network between the differentially expressed genes in the blood of triple negative compared to ER/PR+ breast cancer patients.Notes: Red – genes overexpressed; Green – genes underexpressed ENSG00000161955 ENSG00000188379 ENSG00000099985 ENSG00000006606 PMC6566669__F1 Set of motor neuron proteins in the MAPK signaling pathway ENSG00000070831 ENSG00000130522 PMC12068639__F2 TRIM proteins positively regulate innate immune signaling pathways ENSG00000132109 ENSG00000213928 ENSG00000106785 ENSG00000112343 ENSG00000146833 ENSG00000171206 ENSG00000169871 ENSG00000141569 ENSG00000276561 ENSG00000127445 ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000132256 ENSG00000121060 ENSG00000164342 PMC9319447__F4 Identification, Characteristics and Function of Phosphoglucomutase (PGM) in the Agar Biosynthesis and Carbon Flux in the Agarophyte Gracilariopsis lemaneiformis (Rhodophyta) ENSG00000150787 PMC4765060__F5 Canonical pathway analysis ENSG00000141639 ENSG00000173039 ENSG00000213341 ENSG00000036828 ENSG00000126458 ENSG00000084774 ENSG00000115317 ENSG00000026103 PMC4051169__F8 Mitotic roles of Polo-like kinase pathway ENSG00000105325 ENSG00000065613 ENSG00000134982 ENSG00000177084 ENSG00000117399 ENSG00000276876 PMC3415586__F2 Estrogen receptors regulate an inflammatory pathway of dendritic cell differentiation: mechanisms and implications for immunity ENSG00000137265 PMC4931361__F1 Intrinsic and extrinsic apoptotic signalling pathways and points of therapeutic intervention ENSG00000168040 PMC6712451__F5 Subnetworks of special pathogenic pathways corresponded to different metastasis lesions ENSG00000138795 ENSG00000090905 ENSG00000138798 ENSG00000113070 ENSG00000129691 ENSG00000020633 ENSG00000174804 ENSG00000131095 ENSG00000137801 ENSG00000102145 ENSG00000177426 ENSG00000159216 ENSG00000136997 ENSG00000055609 ENSG00000001626 ENSG00000157450 ENSG00000272333 ENSG00000146648 ENSG00000078687 ENSG00000080839 ENSG00000178568 ENSG00000114166 PMC6109778__F3 Simplified ketone body metabolic pathway ENSG00000167107 ENSG00000122971 ENSG00000075239 ENSG00000275544 ENSG00000117305 ENSG00000127884 PMC11117695__F9 MAs protect IPEC-1 cells from H2O2-induced oxidative stress, inflammation and tight junction protein disruption via activating the Nrf2 pathway to inhibit the ROS/NLRP3/IL-1B signaling pathway ENSG00000162711 ENSG00000181019 ENSG00000175793 PMC4445654__F1 Atlas of tissue renin-angiotensin-aldosterone system in human: A transcriptomic meta-analysis ENSG00000064601 ENSG00000197081 ENSG00000254986 ENSG00000198610 ENSG00000138792 ENSG00000100448 ENSG00000180772 ENSG00000143839 ENSG00000172009 ENSG00000122787 ENSG00000176393 ENSG00000113441 ENSG00000196549 ENSG00000123213 ENSG00000130234 ENSG00000179142 ENSG00000146648 ENSG00000176387 PMC1664647__F1 Schematic representation of the Fas pathway used in the mechanistic model ENSG00000138794 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC6918121__F1 Molecular composition, biogenesis, secretion, and uptake of the exosomes ENSG00000085117 ENSG00000074319 ENSG00000110651 ENSG00000010278 ENSG00000135404 PMC5343412__F7 Phylogenetic relationships of algae thiorredoxin-like ferredoxin domains ENSG00000047936 ENSG00000116649 PMC8082066__F7 SIRT1 Deacetylates TET2 and Promotes Its Ubiquitination Degradation to Achieve Neuroprotection Against Parkinson's Disease ENSG00000135446 ENSG00000096717 PMC6280608__F6 The search page of prescription category as seen by submitting different names ENSG00000143839 PMC2712749__F1 T cell receptor signalling canonical pathway obtained by IPA obtained in comparison MM8_PM8 ENSG00000177971 ENSG00000213658 PMC6280608__F2 The shared targets and pathways in Yu Ping Feng ENSG00000142192 ENSG00000213658 ENSG00000105251 PMC9204954__F2 Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia ENSG00000129167 ENSG00000115271 PMC4826167__F2 The role of the oncofetal H19 lncRNA in tumor metastasis ENSG00000168036 PMC8196589__F1 Estrogens and Progestogens in Triple Negative Breast Cancer: Do They Harm? ENSG00000291971 ENSG00000146648 PMC4837658__F1 Mouse T cell development ENSG00000157554 ENSG00000157404 ENSG00000138795 ENSG00000122025 ENSG00000157557 ENSG00000104903 ENSG00000159216 ENSG00000162676 ENSG00000135363 ENSG00000107485 ENSG00000283060 ENSG00000114315 ENSG00000168685 PMC9513977__F5 Mechanism of abscisic acid regulation of wild Fragaria species in response to cold stress ENSG00000113492 ENSG00000179761 ENSG00000016391 PMC4696971__F2 NOD-Like Receptors in Infection, Immunity, and Diseases ENSG00000273992 ENSG00000162711 ENSG00000167207 ENSG00000091592 ENSG00000274571 ENSG00000142405 ENSG00000172936 ENSG00000091106 ENSG00000175104 ENSG00000106100 ENSG00000276068 PMC2847023__F3 Vitamin D3-driven signals for myeloid cell differentiation - Implications for differentiation therapy ENSG00000170458 PMC8869775__F1 Assays Used for Discovering Small Molecule Inhibitors of YAP Activity in Cancers ENSG00000114978 ENSG00000150457 ENSG00000131023 PMC8065657__F1 Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)/death receptor signaling in the regulation of apoptosis and metastasis of cancer cells ENSG00000137275 ENSG00000291971 ENSG00000168040 ENSG00000127191 ENSG00000168610 PMC7199609__F2 Noncanonical functions of MAPK are emerging targets for BRAFV600E-mutated cancers ENSG00000164430 ENSG00000157764 ENSG00000087842 PMC5830368__F2 Current evidence for extracellular vesicle crosstalk in the homeostatic bone marrow microenvironment ENSG00000178860 ENSG00000132855 ENSG00000162692 ENSG00000136859 PMC12146543__F4 Integrative figure of molecular mechanism of traditional Chinese medicine (TCM) monomers-loaded exosomes for the treatment of cerebral ischemia and reperfusion (CI/R) PMC12146543__F3 Integrative figure of molecular mechanism of traditional Chinese medicine (TCM) monomers-loaded exosomes for the treatment of neurodegenerative disease ENSG00000142192 ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC101920__F1 Late steps of AdoCbl biosynthesis in S ENSG00000142192 ENSG00000082212 PMC4641948__F2 Thrombin effects in endothelial cells involve S1P signaling ENSG00000163914 ENSG00000183018 PMC6803569__F4 PVT1 participates in the downstream signaling pathway of c-Myc by regulating key molecules ENSG00000122691 ENSG00000135446 ENSG00000171791 ENSG00000159399 PMC7198842__F3 Chronic phase-CHIKV mediated joint pathology: in the joints, osteoblast cells (Bone-forming cells) are susceptible to CHIKV infection causing over-expression of IL-6 and RANKL and inhibition of osteoprotegerin (OPG) ENSG00000108691 ENSG00000175104 ENSG00000111816 PMC3402799__F2 Networks generated by Ingenuity Pathway Analysis of the expression signature ENSG00000134308 ENSG00000276644 ENSG00000166266 ENSG00000185518 ENSG00000101152 ENSG00000065613 ENSG00000069431 ENSG00000213023 ENSG00000166073 ENSG00000284099 ENSG00000116985 ENSG00000197386 ENSG00000157103 ENSG00000135503 ENSG00000157551 ENSG00000168060 ENSG00000278693 ENSG00000278195 ENSG00000162366 ENSG00000104899 ENSG00000125384 ENSG00000120693 ENSG00000197208 ENSG00000145920 ENSG00000160741 ENSG00000124568 ENSG00000162009 ENSG00000124357 ENSG00000109572 ENSG00000134070 ENSG00000180616 ENSG00000139190 ENSG00000196517 PMC5719148__F1 Models for post-translational control of CHMP5 during T-cell development ENSG00000171791 ENSG00000086065 PMC7920452__F4 Representation of the gastrointestinal signaling pathway ENSG00000150594 ENSG00000186847 ENSG00000065361 ENSG00000160867 ENSG00000185479 ENSG00000167754 ENSG00000019186 ENSG00000136848 ENSG00000277069 ENSG00000006606 ENSG00000090932 PMC4571319__F1 ERRs are key transcriptional factors that regulate cellular energy metabolism ENSG00000117054 ENSG00000074800 ENSG00000112695 ENSG00000100412 ENSG00000288174 ENSG00000117118 ENSG00000184076 ENSG00000146411 ENSG00000105953 ENSG00000159399 ENSG00000062485 PMC11019495__F3 Recent advances of nanoparticles on bone tissue engineering and bone cells ENSG00000152785 PMC7920452__F3 Representation of the dermatological signaling pathway ENSG00000095917 ENSG00000092445 ENSG00000178078 ENSG00000186395 ENSG00000117152 ENSG00000076706 ENSG00000124875 ENSG00000184292 ENSG00000096264 ENSG00000163435 ENSG00000129214 ENSG00000137077 ENSG00000132517 ENSG00000158258 ENSG00000134531 PMC5574901__F2 Most significantly relevant pathways and highly linked molecules (identified molecules from 17 preclinical studies which to explore the potential mechanisms of TLs for pancreatic cancer) relevant to the merged bionetwork ENSG00000168209 ENSG00000177426 ENSG00000157557 ENSG00000198793 ENSG00000185591 ENSG00000169032 ENSG00000112715 ENSG00000283060 ENSG00000114315 ENSG00000149554 PMC8773784__F2 Nephropathic Cystinosis: Pathogenic Roles of Inflammation and Potential for New Therapies ENSG00000273992 ENSG00000162711 ENSG00000125538 PMC6628503__F6 Proposed model of gga- miR-1306-5p regulation on activation of pro-inflammatory responses via targeting Tollip in chickens (Red arrow: up-regulation or down-regulation) ENSG00000125538 ENSG00000172936 ENSG00000184216 PMC8269128__F3 Hypoxia and Hypoxia-Inducible Factor Signaling in Muscular Dystrophies: Cause and Consequences ENSG00000009709 ENSG00000111049 ENSG00000122180 PMC8658031__F4 Natural Bioactive Molecules: An Alternative Approach to the Treatment and Control of COVID-19 ENSG00000162711 ENSG00000150782 ENSG00000130234 ENSG00000131323 PMC8269128__F4 Hypoxia and Hypoxia-Inducible Factor Signaling in Muscular Dystrophies: Cause and Consequences ENSG00000074800 ENSG00000171791 ENSG00000159399 PMC3642384__F2 Hypothetical evolutionary and functional relationship between Beta-catenin and nuclear transport receptors ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000132341 PMC9569508__F3 Drosophila as a Model Organism to Study Basic Mechanisms of Longevity ENSG00000101751 ENSG00000158104 ENSG00000166169 PMC9569508__F4 Drosophila as a Model Organism to Study Basic Mechanisms of Longevity ENSG00000162924 ENSG00000168040 PMC3893888__F4 Signal transduction pathways leading to increased HIF-1A protein levels PMC5622284__F4 Upregulated genes involved in apoptosis signaling at 1 day after a single dose of 2 Gy Fe ions ENSG00000182511 ENSG00000226275 ENSG00000002330 ENSG00000102871 ENSG00000136997 PMC3724057__F7 MOMA analysis identifies double-gene knockouts in primary metabolism that funnel carbon toward DHA ENSG00000122966 ENSG00000172005 PMC5622284__F6 Irradiated ECs differentially expressed proteins after X-ray exposure involved in caveolar-mediated endocytosis and cell-cell adhesion ENSG00000170558 ENSG00000168374 ENSG00000168036 ENSG00000137076 ENSG00000108518 ENSG00000196396 PMC7400218__F5 Cervical cancer in low and middle-income countries ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC139817__F7 Regulatory interactions between SRF and TCF ENSG00000069482 ENSG00000075142 ENSG00000163914 PMC3498232__F9 Expression Profile in Rice Panicle: Insights into Heat Response Mechanism at Reproductive Stage ENSG00000105722 ENSG00000105227 PMC5622284__F2 Upregulated genes involved in cell cycle regulated processes at 7 days after a single dose of 2 Gy X-rays ENSG00000112576 ENSG00000105329 ENSG00000134982 ENSG00000134308 ENSG00000196591 ENSG00000184182 ENSG00000087586 ENSG00000197629 ENSG00000250254 ENSG00000058804 ENSG00000112118 ENSG00000205250 ENSG00000073111 ENSG00000145386 ENSG00000118971 ENSG00000166851 ENSG00000134480 ENSG00000175054 ENSG00000171720 ENSG00000112242 ENSG00000143761 ENSG00000115942 ENSG00000135336 ENSG00000014138 ENSG00000076382 ENSG00000108106 ENSG00000253729 ENSG00000282899 ENSG00000133895 ENSG00000123975 ENSG00000170027 ENSG00000101057 ENSG00000149311 ENSG00000145604 ENSG00000134057 ENSG00000198176 ENSG00000061273 ENSG00000132646 ENSG00000147082 ENSG00000080839 ENSG00000175305 PMC2635620__F2 Inhibition of each signaling molecules by natural products in insulin signaling ENSG00000291971 ENSG00000198793 PMC6526932__F1 Targeting cancer vulnerabilities with high-dose vitamin C PMC4365328__F1 HA precursors biosynthesis and main HAS2 regulation in SMCs ENSG00000109814 ENSG00000170961 ENSG00000159224 ENSG00000147162 PMC4611209__F1 Sporadic traditional/CIN/suppressor pathway: sequential pathological stages and molecular events ENSG00000134982 ENSG00000078098 PMC7981899__F1 Chemokines and their receptors’ roles in acute lymphoblastic leukemia ENSG00000186810 ENSG00000107562 ENSG00000291603 ENSG00000131142 ENSG00000148400 ENSG00000291971 ENSG00000136997 ENSG00000126353 ENSG00000100985 ENSG00000168610 PMC5408584__F5 Fatty acid binding protein-1 (FABP1) and the human FABP1 T94A Variant: Roles in the Endocannabinoid System and Dyslipidemias ENSG00000138744 ENSG00000117480 ENSG00000026103 PMC5408584__F4 Fatty acid binding protein-1 (FABP1) and the human FABP1 T94A Variant: Roles in the Endocannabinoid System and Dyslipidemias ENSG00000157184 ENSG00000138744 ENSG00000117480 ENSG00000026103 PMC4235722__F2 Conservation between the Drosophila and the mammalian JAK/STAT pathway and their commonalities in inducing systemic and localized immune response and tissue growth ENSG00000142166 PMC3782367__F1 Unfolded protein response (UPR) is activated in the autosomal dominant retinitis pigmentosa (adRP) retina and proposed to be a target for modulating the rate of retinal degeneration ENSG00000143799 ENSG00000100290 ENSG00000105392 ENSG00000128272 ENSG00000144895 ENSG00000198793 ENSG00000163914 ENSG00000285493 ENSG00000127191 PMC8897452__F6 Colorectal liver metastasis: molecular mechanism and interventional therapy ENSG00000148400 ENSG00000074181 ENSG00000026508 ENSG00000133961 ENSG00000135097 PMC11552248__F1 Adhesin RadD: the secret weapon of Fusobacterium nucleatum ENSG00000181847 ENSG00000132646 ENSG00000100985 PMC8897452__F7 Colorectal liver metastasis: molecular mechanism and interventional therapy ENSG00000168610 ENSG00000121966 PMC4671959__F7 Mechanism of the Redox-Dependent Brf2 Blockade during Oxidative Stress and Carcinogenesis, Related to , , , , , , and During normal growth conditions (A) Brf2- and Nrf2-dependent transcripts are synthesized at basal levels ENSG00000104221 PMC5454446__F2 ‘Eat-me' signals, phagocytic machinery and signaling pathways ENSG00000136011 ENSG00000153208 ENSG00000144366 ENSG00000145794 PMC6964096__F4 Wiki pathway analysis of the differentially expressed proteins (DEPs) during rhesus hippocampal aging ENSG00000110700 ENSG00000131469 ENSG00000124614 ENSG00000198755 ENSG00000105193 ENSG00000130414 ENSG00000156482 ENSG00000141564 ENSG00000176533 ENSG00000100485 ENSG00000116251 ENSG00000108107 ENSG00000172037 ENSG00000166136 ENSG00000280858 ENSG00000103479 ENSG00000107263 ENSG00000105640 ENSG00000149273 ENSG00000110717 ENSG00000175766 ENSG00000170899 ENSG00000114450 ENSG00000166441 ENSG00000160194 ENSG00000108298 ENSG00000078369 ENSG00000164587 ENSG00000142534 ENSG00000198242 ENSG00000161970 ENSG00000213341 ENSG00000004779 ENSG00000278270 ENSG00000132356 ENSG00000174444 ENSG00000083845 ENSG00000165264 ENSG00000178127 ENSG00000161016 ENSG00000267855 ENSG00000183648 ENSG00000109390 ENSG00000213619 ENSG00000065518 ENSG00000151366 ENSG00000189043 ENSG00000182774 ENSG00000131495 ENSG00000073578 ENSG00000182899 ENSG00000117118 ENSG00000136854 ENSG00000137818 ENSG00000198793 ENSG00000171863 ENSG00000242616 ENSG00000125691 ENSG00000197958 ENSG00000115364 ENSG00000119396 ENSG00000177600 ENSG00000171105 ENSG00000172380 ENSG00000151012 ENSG00000116044 ENSG00000147684 ENSG00000109320 ENSG00000111713 ENSG00000173039 ENSG00000281877 ENSG00000143252 ENSG00000142541 ENSG00000177189 ENSG00000174748 ENSG00000109475 ENSG00000162409 ENSG00000129824 ENSG00000167996 ENSG00000099795 ENSG00000119013 ENSG00000112306 ENSG00000114279 ENSG00000262243 PMC3653945__F6 Toll-Like Receptor -1, -2, and -6 Polymorphisms and Pulmonary Tuberculosis Susceptibility: A Systematic Review and Meta-Analysis ENSG00000174125 ENSG00000177606 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC9588339__F5 Exploring Anti-Type 2 Diabetes Mellitus Mechanism of Gegen Qinlian Decoction by Network Pharmacology and Experimental Validation ENSG00000131323 ENSG00000127191 PMC6724083__F2 Hypothetical network of metabolism in F ENSG00000115419 ENSG00000062485 PMC7770494__F33 International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function ENSG00000070831 ENSG00000077279 ENSG00000196712 PMC4224695__F3 Interactions of Acvr1b with other proteins in primary infection ENSG00000075856 ENSG00000284774 ENSG00000100568 ENSG00000102317 ENSG00000139567 ENSG00000205302 ENSG00000166402 ENSG00000168610 ENSG00000123124 ENSG00000196531 ENSG00000171566 ENSG00000110395 ENSG00000129214 ENSG00000263528 ENSG00000291791 ENSG00000028528 ENSG00000102104 ENSG00000256646 ENSG00000166228 ENSG00000114739 PMC7097117__F4 ISG15 in antiviral immunity and beyond ENSG00000184979 ENSG00000187608 ENSG00000138642 ENSG00000121060 PMC3311926__F1 Mitochondrial regulation of apoptosis PMC5490213__F5 Representation of secondary metabolic pathway genes and tissue specific expression in response to MeJA and wounding in Bacopa monnieri ENSG00000197429 ENSG00000113161 ENSG00000084774 PMC7097117__F1 ISG15 in antiviral immunity and beyond ENSG00000213928 ENSG00000005339 ENSG00000187608 ENSG00000185436 ENSG00000276561 ENSG00000142166 ENSG00000184979 ENSG00000183735 ENSG00000166233 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000138642 ENSG00000136869 ENSG00000121060 PMC5709539__F1 Emerging mechanisms underlying astrogenesis in the developing mammalian brain ENSG00000168036 ENSG00000131095 PMC5993950__F2 DYSREGULATION OF mRNA TRANSLATION AND ENERGY METABOLISM IN CANCER ENSG00000167658 PMC3743503__F8 GeneGo pathway map translation regulation of eIF2 activity ENSG00000145191 ENSG00000138798 ENSG00000146648 ENSG00000127334 ENSG00000086232 PMC8122391__F3 Overcoming the Immunosuppressive Tumor Microenvironment in Multiple Myeloma ENSG00000002330 ENSG00000168610 PMC3743503__F9 Evidence for indirect influence of kinases on tau phosphorylation ENSG00000123374 ENSG00000185591 ENSG00000173846 ENSG00000086232 PMC8059748__F1 PI3 kinase signaling pathway ENSG00000002330 ENSG00000198793 PMC8100938__F3 Platelets orchestrate the prothrombotic immune response in venous thrombosis ENSG00000150782 ENSG00000110799 ENSG00000189403 PMC4918253__F2 Canonical and noncanonical pathways of inflammasome activation.Notes: (A) Canonical inflammasome activation (canonical pathway) ENSG00000125538 ENSG00000136869 PMC6365678__F7 CXCL16/CXCR6 interaction promotes endometrial decidualization via PI3K-PDK1-AKT-Cyclin D1 pathway ENSG00000161921 ENSG00000146678 PMC5419541__F3 Signaling Pathways for Permitting Cross Talk between WNT and GnRHThe shaded pathway represents the skeletal features of the canonical Wnt/Beta-catenin signal transduction pathway ENSG00000070831 ENSG00000291971 ENSG00000134982 ENSG00000177606 ENSG00000168036 PMC4918253__F1 Schematic view of the TLR4 signaling pathway.Notes: Upon binding of lipopolysaccharide (LPS) to the TLR4 complex (TLR4–LBP–CD14–MD2), TLR4 signals through MyD88-dependent and/or MyD88-independent pathways ENSG00000183735 ENSG00000170458 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC8196612__F3 Neuroprotective and Immunomodulatory Action of the Endocannabinoid System under Neuroinflammation ENSG00000117480 ENSG00000196689 ENSG00000147262 PMC4835495__F2 Control of the FA pathway by SUMO and SUMO-like modifications ENSG00000012061 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000112701 ENSG00000163961 ENSG00000063978 ENSG00000144554 ENSG00000188827 ENSG00000132646 ENSG00000033800 ENSG00000162607 PMC4383338__F9 Scavenger Receptor SREC-I Mediated Entry of TLR4 into Lipid Microdomains and Triggered Inflammatory Cytokine Release in RAW 264.7 Cells upon LPS Activation ENSG00000170458 ENSG00000172936 ENSG00000136869 PMC10836493__F3 Mechanism by which GPX3 is involved in maintaining the stemness of OCSCs in the TME ENSG00000211445 ENSG00000042832 ENSG00000026508 ENSG00000099194 PMC4113420__F4 PCNA and Msh2-Msh6 Activate an Mlh1-Pms1 Endonuclease Pathway Required for Exo1-independent Mismatch Repair ENSG00000132646 ENSG00000064933 PMC11810530__F2 IHD‐mediated pyroptosis occurs through canonical, noncanonical and alternative pathways ENSG00000278718 ENSG00000162711 ENSG00000136869 ENSG00000131323 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC11810530__F1 Pyroptosis signalling cascade in IHD involves a series of events ENSG00000278718 ENSG00000162711 ENSG00000136869 ENSG00000131323 PMC12074965__F5 UDP-GlcNAc And CMP-Neu5Ac Synthesis In Mammary Epithelial Cells: In the cytoplasm, glucose (Glu) enters the cell via glucose transporter 1 (GLUT1) and is phosphorylated by hexokinase (HK) to form glucose-6-phosphate (Glu-6-P) ENSG00000159921 ENSG00000170191 ENSG00000111726 ENSG00000095380 PMC2778342__F2 Roles of the selected genes in the DSBR pathway ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000136492 ENSG00000079246 ENSG00000164754 ENSG00000051180 ENSG00000256683 ENSG00000139618 ENSG00000183765 PMC3053440__F1 Toll-like receptor signaling pathway ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC3423541__F2 Biological targets under investigation for treatment of SLE ENSG00000198793 ENSG00000137265 PMC11998019__F3 Exploration of Traditional Chinese Medicine Comprehensive Treatment of Triple Negative Breast Cancer Based on Molecular Pathological Mechanism ENSG00000143815 ENSG00000198793 ENSG00000168036 ENSG00000128342 PMC6381741__F2 Differential expression of A ENSG00000128272 ENSG00000144895 PMC7933966__F6 Schematic underlying mediation mechanism of CRKL on glucose metabolism in hepatocarcinoma ENSG00000099942 PMC4651023__F4 Biophysical Approaches for Oral Wound Healing: Emphasis on Photobiomodulation ENSG00000177606 ENSG00000173039 PMC8053626__F6 The mechanism of abnormal cholesterol transport in the 827G cybrids ENSG00000138075 ENSG00000113161 ENSG00000143921 PMC7851442__F2 DCs in cancer therapies ENSG00000122025 ENSG00000169245 ENSG00000162711 ENSG00000186810 ENSG00000164430 ENSG00000138755 ENSG00000089041 ENSG00000189403 ENSG00000136869 ENSG00000164342 PMC8283010__F3 Matrix Metalloproteinase 3: A Promoting and Destabilizing Factor in the Pathogenesis of Disease and Cell Differentiation ENSG00000172216 ENSG00000149968 ENSG00000125538 ENSG00000127191 ENSG00000122194 PMC7183768__F8 CREB signaling in neurons in response to granisetron treatment with the IPA molecule activity predictor PMC5328851__F2 Schematic diagram demonstrating the mechanism of action of perlecan and endorepellin in angiogenesis and autophagy ENSG00000198793 ENSG00000112715 ENSG00000198300 PMC3695728__F2 Exploring mechanisms of FGF signalling through the lens of structural biology ENSG00000002330 ENSG00000124181 PMC7010080__F2 NAD+ in cancer metabolic reprogramming ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000283100 PMC12074965__F2 Glycosyltransferases: glycoengineers in human milk oligosaccharide synthesis and manufacturing ENSG00000069482 PMC7010080__F1 Compartmentalized NAD+ metabolome in humans ENSG00000143799 ENSG00000187531 ENSG00000123572 ENSG00000278488 ENSG00000157064 ENSG00000124523 ENSG00000077463 ENSG00000173614 ENSG00000096717 ENSG00000142082 ENSG00000089163 ENSG00000283100 PMC7781229__F1 Mechanism and function of therapy-induced senescence ENSG00000149311 ENSG00000175054 ENSG00000101945 ENSG00000135446 ENSG00000105810 ENSG00000140464 PMC10244546__F1 Potential of epigallocatechin gallate in the chemoprevention and therapy of hepatocellular carcinoma ENSG00000198793 ENSG00000110651 ENSG00000168610 PMC9112071__F6 Chromosome-Level Genome of the Camphor Tree and the Underlying Genetic and Climatic Factors for Its Top-Geoherbalism ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC11946974__F1 Bitter Taste Signaling Pathway ENSG00000185933 ENSG00000183128 ENSG00000070985 PMC11200880__F1 Oxytocin signaling brain pathway ENSG00000124140 ENSG00000115474 ENSG00000144895 ENSG00000116741 ENSG00000136869 ENSG00000166484 ENSG00000146648 ENSG00000196689 PMC12095162__F3 NOD2 receptor signaling pathway ENSG00000167207 ENSG00000157625 PMC8442909__F4 Characterization of the Potential Role of NTPCR in Epithelial Ovarian Cancer by Integrating Transcriptomic and Metabolomic Analysis ENSG00000117228 ENSG00000183486 ENSG00000276561 PMC9049047__F1 All roads lead to DSBs ENSG00000012048 ENSG00000051180 ENSG00000139618 PMC6669812__F2 Leptin binds to the LEPR and mediates multiple downstream pathways ENSG00000137673 ENSG00000198793 ENSG00000168610 ENSG00000084774 PMC7775514__F1 Toll-like receptor 4 (TLR4) signaling in Alzheimer disease (AD) ENSG00000183735 ENSG00000135218 ENSG00000070831 ENSG00000170458 ENSG00000189403 ENSG00000197943 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC7916307__F2 IAP-p53 axis is an essential regulator of a multitude of cellular pathways ENSG00000132530 ENSG00000089685 ENSG00000033800 ENSG00000196591 ENSG00000168610 ENSG00000146648 ENSG00000113360 ENSG00000276068 PMC8998929__F3 Hippo Signaling in the Endometrium ENSG00000101109 PMC8998929__F1 Hippo Signaling in the Endometrium ENSG00000101109 ENSG00000198793 ENSG00000139926 PMC5360391__F6 Proposed hypothesis for the effect of melittin on formation of osteoclast-like MNCs ENSG00000125538 ENSG00000175104 ENSG00000131196 PMC5665463__F6 Model for HCN4 function in establishing laterality ENSG00000138622 ENSG00000156574 ENSG00000164093 PMC3733232__F1 TGFBeta-mediated signaling and transcriptional regulation in pancreatic development and cancer ENSG00000111537 ENSG00000138798 ENSG00000125538 PMC6943435__F1 Metabolic remodelling in lung cancer ENSG00000131473 ENSG00000173599 ENSG00000146648 ENSG00000159399 PMC9049047__F5 All roads lead to Gaps ENSG00000012048 ENSG00000051180 ENSG00000175857 ENSG00000139618 PMC3381938__F5 Alternative Macrophage Activation and Metabolism ENSG00000118520 ENSG00000026103 PMC3778921__F4 Integrative Analysis Reveals an Outcome-associated and Targetable Pattern of p53 and Cell Cycle Deregulation in Diffuse Large B-cell Lymphoma ENSG00000112576 ENSG00000126453 ENSG00000161970 ENSG00000171791 ENSG00000132510 ENSG00000103479 ENSG00000114126 ENSG00000198176 ENSG00000135446 ENSG00000123374 ENSG00000112378 ENSG00000105810 ENSG00000139687 ENSG00000026103 ENSG00000198625 PMC2771153__F9 Schematic presentation of a model of induction of beta cell apoptosis during viral infections ENSG00000089127 ENSG00000135828 ENSG00000164342 PMC10966608__F4 EcDNA in drug resistance ENSG00000228716 ENSG00000157764 ENSG00000146648 PMC6858087__F1 Structural variability in the RLR-MAVS pathway and sensitive detection of viral RNAs ENSG00000088888 ENSG00000082512 ENSG00000175104 ENSG00000127191 PMC5522741__F1 Aging is a complicated process, often characterized by increased ROS and inflammation ENSG00000150907 ENSG00000096717 PMC4076843__F2 Use of natural AhR ligands as potential therapeutic modalities against inflammatory disorders ENSG00000140465 ENSG00000106546 PMC3151428__F3 Suppression of anaerobic metabolism by p53 is mediated through multiple pathways ENSG00000078237 ENSG00000159399 PMC12131575__F6 Schematic diagram showing the possible mechanism of noise-induced cognitive decline ENSG00000118515 PMC9288732__F2 Crosstalk of organelles in Parkinson’s disease – MiT family transcription factors as central players in signaling pathways connecting mitochondria and lysosomes ENSG00000129003 ENSG00000184381 ENSG00000198793 ENSG00000158828 ENSG00000069329 ENSG00000182220 PMC5912981__F1 GCN5L1/BLOS1 links acetylation, organelle remodeling and metabolism ENSG00000141665 ENSG00000112561 PMC8236063__F8 Mechanistic scheme of DNA-methylation-mediated RSPO2 regulating GCs proliferation, apoptosis and E2 secretion ENSG00000145321 ENSG00000168036 PMC5835171__F1 INNATE IMMUNE CONTROL OF ALPHAVIRUS INFECTION ENSG00000187608 ENSG00000059378 ENSG00000185745 ENSG00000142089 ENSG00000111331 ENSG00000135828 ENSG00000178685 PMC4382242__F2 Autophagy in cellular metabolism and cancer ENSG00000177169 ENSG00000057663 PMC9106601__F1 WNT and NOTCH signaling in human trophoblast development and differentiation ENSG00000134982 ENSG00000168036 ENSG00000185269 PMC2766863__F2 Signalling crosstalk in B cells: managing worth and need ENSG00000177455 ENSG00000095585 ENSG00000104856 ENSG00000186716 ENSG00000197943 ENSG00000162924 ENSG00000131323 ENSG00000127191 PMC7411000__F1 Illustration of BPA on LC development ENSG00000073060 PMC3525024__F7 Schematic representation of canonical and noncanonical Hh signaling activation in MM ENSG00000164690 ENSG00000128602 PMC8578498__F4 VGF as a biomarker and therapeutic target in neurodegenerative and psychiatric diseases ENSG00000198793 ENSG00000128564 ENSG00000008056 PMC8701796__F6 Genome-Wide RNA-Sequencing Reveals Massive Circular RNA Expression Changes of the Neurotransmission Genes in the Rat Brain after Ischemia–Reperfusion ENSG00000065135 ENSG00000114450 ENSG00000161681 ENSG00000144935 ENSG00000078369 ENSG00000162105 ENSG00000174021 PMC3628696__F5 Ingenuity Pathway Analysis (IPA) was performed with proteins where SUMO3 conjugation was 2- or more fold up-regulated in any gel slice ENSG00000159216 ENSG00000113649 ENSG00000269405 ENSG00000196498 ENSG00000169813 ENSG00000116030 ENSG00000100146 ENSG00000166886 ENSG00000105323 ENSG00000140464 ENSG00000184900 ENSG00000110693 PMC10743592__F2 Presentation of the action of ghrelin on autophagy ENSG00000177169 ENSG00000083290 ENSG00000198793 PMC10743592__F3 Presentation of association between apoptosis and necroptosis ENSG00000137275 ENSG00000102871 ENSG00000171791 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC7395694__F9 Model for miR-214 regulation upon CC cell progression ENSG00000168610 ENSG00000101213 PMC5980154__F6 Schematic diagram illustrating how ɑ‐LA, via regulation of Grb2 expression, modulates different signalling pathways that participate in proliferation‐related stress responses ENSG00000019991 ENSG00000291971 ENSG00000138798 ENSG00000198793 PMC7260346__F5 De novo transcriptome analysis unravels tissue-specific expression of candidate genes involved in major secondary metabolite biosynthetic pathways of Plumbago zeylanica: implication for pharmacological potential ENSG00000136152 ENSG00000148798 PMC8741861__F10 Follicle stimulating hormone and its receptors in reproduction and in stem cells and cancer stem cells ENSG00000157500 PMC4666507__F1 Described mechanisms involved in steroid hormone regulation of cancer stem cell populations ENSG00000135111 ENSG00000107485 ENSG00000102678 ENSG00000146648 ENSG00000136826 PMC11640042__F1 Wnt signaling pathway ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8222790__F4 Cellular Metabolomics Profiles Associated With Drug Chemosensitivity in AML ENSG00000154059 PMC11640042__F3 Wnt Signaling in Hepatocellular Carcinoma: Biological Mechanisms and Therapeutic Opportunities ENSG00000169908 ENSG00000281324 ENSG00000162337 ENSG00000130700 ENSG00000134982 ENSG00000168036 ENSG00000104332 PMC11640042__F2 Wnt signaling regulates HCC biological behavior ENSG00000087095 ENSG00000129194 ENSG00000176887 ENSG00000133169 ENSG00000020633 ENSG00000138100 ENSG00000105810 ENSG00000134046 ENSG00000050405 ENSG00000196628 ENSG00000221926 ENSG00000133216 PMC1781473__F3 Exploitation of Eukaryotic Ubiquitin Signaling Pathways by Effectors Translocated by Bacterial Type III and Type IV Secretion Systems ENSG00000285246 ENSG00000157625 PMC8046533__F3 KEGG Pathway analysis of IFNg protein in tuberculosis disease ENSG00000132906 ENSG00000110514 ENSG00000170458 ENSG00000148798 ENSG00000136997 ENSG00000113520 PMC7527722__F7 Klebsiella pneumoniae ablates SUMOylation via distinct pathways in epithelial cells or macrophages ENSG00000163904 ENSG00000285246 ENSG00000136869 ENSG00000146648 PMC5753009__F3 ATX-LPA axis promotes cancer-related inflammation ENSG00000291971 ENSG00000198793 ENSG00000177606 ENSG00000164362 ENSG00000198670 ENSG00000100985 ENSG00000168610 PMC7246870__F5 Ingenuity Pathway Analysis (IPA) of five genes (CXCL10, FOS, UBE2N, IL1A, and TLR4) that are commonly regulated by both regorafenib and lenvatinib showed a close association with cell proliferation signaling pathways (red color) ENSG00000115008 ENSG00000136869 PMC5938431__F3 Interferon regulatory factor 1 inactivation in human cancer ENSG00000136492 ENSG00000187608 ENSG00000105397 ENSG00000123374 PMC4008226__F8 A mechanism for integrated regulation of motility and adhesion in T cells and its role for transendothelial migration ENSG00000107562 ENSG00000121966 PMC4342183__F6 MAPK signaling pathway in the target list of hsa-miR-181a-5p based on miRTarBase 4.0.Notes: hsa-miR-181a-5p can regulate MAPK signaling pathways ENSG00000087095 ENSG00000170458 ENSG00000130522 ENSG00000149269 ENSG00000138798 ENSG00000127191 ENSG00000146648 ENSG00000081189 ENSG00000026103 PMC3980725__F1 PI3K pathway inhibitors for the treatment of brain metastases with a focus on HER2+ breast cancer ENSG00000109452 ENSG00000169047 ENSG00000146648 PMC7063406__F2 Epithelial and Epidermal barrier dysfunction: Various molecules involved in the signaling pathways shown in figure are maintaining the epithelial and epidermal barrier ENSG00000172936 ENSG00000146648 ENSG00000070019 PMC4342183__F8 VEGF signaling pathway in the target list of hsa-miR-181a-5p based on miRTarBase 4.0.Notes: hsa-miR-181a-5p can regulate the VEGF signaling pathway ENSG00000132906 ENSG00000002330 ENSG00000070831 ENSG00000291971 PMC3744771__F1 Inhibitory molecules and therapeutic targets within the Rhopathway ENSG00000182175 ENSG00000116106 ENSG00000169783 PMC4342183__F7 Notch signaling pathway in the target list of hsa-miR-181a-5p based on miRTarBase 4.0.Notes: hsa-miR-181a-5p can regulate the function of the Notch signaling pathway ENSG00000273529 ENSG00000133961 ENSG00000114315 PMC5382886__F1 TLR4, MyD88 and TRAF6 down-regulation following glutamine administration in LPS-stimulated peripheral blood leukocytes of pancreatic cancer patients ENSG00000170458 ENSG00000172936 ENSG00000150455 ENSG00000175104 PMC3621284__F2 Proposed role of aPKCs in synaptic plasticity: At most CNS synapses, strong synaptic input leads to an activation of PI3K signaling and PDK1 activation thereby (1) thereby leading to mTORC1 activation ENSG00000163435 PMC3077378__F7 Multifaceted Intervention by the Hsp90 Inhibitor Ganetespib (STA-9090) in Cancer Cells with Activated JAK/STAT Signaling ENSG00000122025 ENSG00000146648 PMC4342183__F2 Wnt signaling pathway in the target list of hsa-miR-181a-5p, based on TarBase 6.0.Notes: hsa-181a-5p is a regulator of Wnt ENSG00000087095 ENSG00000100592 ENSG00000095739 ENSG00000100387 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000168036 ENSG00000196470 PMC4342183__F4 p53 pathway in the target list of hsa-miR-181a-5p, based on TarBase 6.0.Notes: hsa-miR-181a-5p can regulate the p53 signaling pathway ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000039537 ENSG00000006712 ENSG00000136997 ENSG00000112378 ENSG00000196470 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC4342183__F3 Cell cycle pathway in the target list of hsa-miR-181a-5p, based on TarBase 6.0.Notes: hsa-miR-181a-5p can regulate a number of important proteins that control the cell cycle ENSG00000118007 ENSG00000108055 ENSG00000134982 ENSG00000205250 ENSG00000277273 ENSG00000166851 ENSG00000117399 ENSG00000276876 ENSG00000145604 ENSG00000101972 ENSG00000135446 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000105810 PMC7057932__F2 Cellular signaling pathways associated with the mutated genes of the biliary tract cancer (BTC) cases ENSG00000124102 ENSG00000157764 ENSG00000198793 ENSG00000105647 ENSG00000183765 ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000136997 ENSG00000105810 ENSG00000149554 ENSG00000139687 ENSG00000146648 ENSG00000178568 ENSG00000196712 PMC8777554__F2 Wnt/Beta-catenin signal transduction pathway in prostate cancer and associated drug resistance ENSG00000095739 ENSG00000134982 ENSG00000168036 ENSG00000108375 PMC8777554__F1 Wnt/Beta-catenin signal transduction pathway in prostate cancer and associated drug resistance ENSG00000100592 PMC8358957__F2 Endocannabinoid system – current implications for drug development ENSG00000163686 ENSG00000138744 ENSG00000164535 ENSG00000117480 ENSG00000134780 PMC4741978__F3 SNP-SNP interaction analysis of NFKB signaling pathway on breast cancer survival ENSG00000077150 ENSG00000109320 ENSG00000131323 ENSG00000127191 PMC7068866__F6 Metastasis prediction: optimum centered Bayesian network found ENSG00000019485 ENSG00000101782 ENSG00000266265 ENSG00000134369 ENSG00000002746 ENSG00000161681 ENSG00000138755 ENSG00000140464 ENSG00000026103 ENSG00000100811 ENSG00000144642 ENSG00000291559 ENSG00000156486 ENSG00000174705 ENSG00000120693 ENSG00000070495 ENSG00000100987 ENSG00000167981 ENSG00000186376 ENSG00000205730 ENSG00000138759 ENSG00000184374 ENSG00000251369 ENSG00000159714 ENSG00000118785 ENSG00000074266 ENSG00000170779 ENSG00000167646 PMC6201246__F6 Overview of current understanding of the pathogenesis of HIT ENSG00000110799 ENSG00000105656 ENSG00000163737 PMC6273515__F3 Bound sulfur activates the nuclear factor erythroid related factor 2 (Nrf2) system through a structural change of Kelch-like ECH-associated protein 1 (Keap1) and promotion of the AKT/phosphoinositide 3-kinase (PI3K) signaling pathway PMC8638743__F2 Cross Talk Between p53 and mTOR Pathways in Response to Physiological and Genotoxic Stresses ENSG00000198793 ENSG00000198625 PMC8638743__F1 Cross Talk Between p53 and mTOR Pathways in Response to Physiological and Genotoxic Stresses ENSG00000198793 ENSG00000155792 ENSG00000164327 PMC5942188__F1 Review of craniofacial and dental findings of the RASopathies ENSG00000157764 ENSG00000115904 ENSG00000143622 ENSG00000196712 ENSG00000062485 PMC10501637__F5 PPI network analysis of total DEGs in ELMOD3mut and ELMOD3corrected iPSCs ENSG00000145864 ENSG00000148926 ENSG00000124875 ENSG00000070886 ENSG00000171388 ENSG00000106631 ENSG00000133019 ENSG00000110148 ENSG00000148082 ENSG00000157087 ENSG00000115138 ENSG00000143590 ENSG00000168398 ENSG00000102104 ENSG00000132681 ENSG00000169174 ENSG00000011677 ENSG00000113889 ENSG00000143185 ENSG00000081041 ENSG00000107014 ENSG00000166573 ENSG00000110680 ENSG00000060558 ENSG00000124493 ENSG00000169242 ENSG00000274473 ENSG00000277586 ENSG00000118785 ENSG00000126895 ENSG00000136160 ENSG00000156113 ENSG00000115461 PMC3342043__F1 TLR2 signaling ENSG00000174125 ENSG00000115415 ENSG00000134070 ENSG00000172936 ENSG00000168310 ENSG00000150455 ENSG00000125347 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC6689183__F8 Dropwort extract exerts broad anticancer effects on MPM cells affecting cell proliferation, viability, migration, metabolism and in vivo tumor growth of MPM cell lines ENSG00000074590 ENSG00000198793 ENSG00000197905 ENSG00000168036 ENSG00000007866 ENSG00000166508 ENSG00000074219 PMC2723150__F1 Eukaryotic gene expression is controlled by multiple mechanisms, and its regulation is central for physiological responses to extracellular and intracellular signals ENSG00000170191 ENSG00000130643 ENSG00000053438 ENSG00000172005 ENSG00000171540 ENSG00000132341 PMC3159004__F2 TLR-independent innate immune responses ENSG00000166278 ENSG00000131196 PMC5370040__F1 Tumour-derived exosomes as a signature of pancreatic cancer - liquid biopsies as indicators of tumour progression ENSG00000110651 ENSG00000010278 ENSG00000135404 PMC6172067__F5 Prognostic biomarkers in clear cell renal carcinoma ENSG00000135218 ENSG00000066336 ENSG00000113263 ENSG00000112715 PMC5983591__F1 Growth hormone releasing peptide (GHRP)-peroxisome proliferator-activated receptor-gamma (PPARG) pathway in lipid and energy metabolism ENSG00000135218 ENSG00000186480 ENSG00000160179 PMC4118128__F9 The proposed model for the regulation of the IRS-1-PI3K-mTOR pathway by PRCP and PREP ENSG00000169047 ENSG00000198793 ENSG00000137509 PMC7820188__F2 Wnt signaling, structure and activation: Wnt signaling is activated when glycoprotein ligands of the Wnt family bind Frizzled transmembrane receptors located at cell membrane level ENSG00000070831 ENSG00000134982 ENSG00000163914 PMC9404549__F9 Salvia chinensis Benth Inhibits Triple-Negative Breast Cancer Progression by Inducing the DNA Damage Pathway ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000144554 ENSG00000051180 PMC2642591__F1 Retinoic acid dependent regulation of immune responses by dendritic cells and macrophages ENSG00000134982 ENSG00000049768 PMC2254474__F1 P2Y receptor-mediated signalling cascades in C6 cells ENSG00000177606 ENSG00000131095 PMC6687752__F7 CXCR2 expression on granulocyte and macrophage progenitors under tumor conditions contributes to mo-MDSC generation via SAP18/ERK/STAT3 ENSG00000163739 ENSG00000150459 ENSG00000168610 PMC4800795__F10 FAF1 action on the innate-immunity signaling pathway ENSG00000183735 ENSG00000088888 ENSG00000187608 ENSG00000157601 ENSG00000185745 ENSG00000185104 PMC4762492__F1 PI3K/AKT/mTOR signaling pathway and examples of drugs targeting each of its components.Note: RSK, 90 kDa ribosomal protein S6 kinase ENSG00000109452 ENSG00000002330 ENSG00000146648 PMC2818872__F8 Ras signaling in early B cell development ENSG00000120833 ENSG00000121966 PMC11659631__F8 Mechanism of GGO inhibited cervical cancer cell proliferation and angiogenesis ENSG00000136158 ENSG00000087245 ENSG00000198793 ENSG00000100985 PMC10296830__F1 The Hippo pathway and YAP/TAZ mechanosignaling ENSG00000166484 ENSG00000150457 ENSG00000069956 ENSG00000131023 PMC3875462__F1 Regulation of the mTOR signaling pathway ENSG00000266173 PMC3659299__F4 Scheme depicting the current knowledge on PAC1-mediated signaling cascades resulting in a variety of neuronal outcomes ENSG00000291971 ENSG00000132478 PMC4013678__F2 Bayesian Brain Immune and Microglia Module ENSG00000011600 ENSG00000030582 ENSG00000186517 ENSG00000138964 ENSG00000163694 ENSG00000136286 ENSG00000171051 ENSG00000159216 ENSG00000103490 ENSG00000110446 ENSG00000095303 ENSG00000277263 ENSG00000131724 ENSG00000153551 ENSG00000086730 ENSG00000121552 ENSG00000091317 ENSG00000130208 ENSG00000231021 ENSG00000081237 ENSG00000162924 ENSG00000100060 ENSG00000110719 ENSG00000019582 ENSG00000239998 ENSG00000163131 ENSG00000243646 ENSG00000028137 PMC5652852__F1 Chromosomal instability and acquired drug resistance in multiple myeloma ENSG00000012061 ENSG00000104884 ENSG00000134982 ENSG00000117399 PMC4461483__F4 Possible role of Naa10 in cellular hypoxia ENSG00000131473 PMC10943832__F2 Metabolic pathway of tryptophan (Trp) ENSG00000162882 ENSG00000130649 ENSG00000183077 PMC10943832__F5 AhR signaling pathway ENSG00000162711 ENSG00000158290 ENSG00000100387 ENSG00000291971 ENSG00000167986 ENSG00000168036 ENSG00000291938 ENSG00000106546 PMC3469769__F2 Multiple roles of COUP-TFII in cancer initiation and progression ENSG00000175206 ENSG00000114113 ENSG00000110244 ENSG00000129214 ENSG00000128052 ENSG00000124253 PMC5641361__F4 Cell signaling pathway scheme of metabolic alterations due to Zika virus infection ENSG00000064601 ENSG00000196549 ENSG00000130234 ENSG00000198793 ENSG00000115020 ENSG00000163751 PMC8220449__F7 Schematic diagram depicting the effect of TMJ-12 on the PI3K/AKT signaling pathway leading to the induction of apoptosis and cell cycle arrest in BPH-1 cells ENSG00000002330 ENSG00000198793 PMC7330089__F8 Regulatory model of the MBW complexes for juvenile red fading in sweetpotato leaves ENSG00000166278 PMC5404519__F1 Biosynthetic pathway of the major phospholipids in bacteria ENSG00000184207 ENSG00000182326 PMC5992185__F4 Molecular structure, posttranslational modifications, and protein–protein interactions of the Ski and SnoN proteins ENSG00000157933 ENSG00000064393 ENSG00000023287 ENSG00000033800 ENSG00000197905 ENSG00000087586 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 ENSG00000102145 ENSG00000171720 ENSG00000106571 ENSG00000158161 ENSG00000177606 ENSG00000096717 ENSG00000126778 ENSG00000140464 ENSG00000196712 PMC4467754__F14 Scheme of possible mechanisms by which AT-101 enhances the anticancer activity of CDDP in NSCLC ENSG00000108924 ENSG00000196092 ENSG00000168610 PMC5641207__F1 Single-cell genomic analysis of head and neck squamous cell carcinoma ENSG00000136997 ENSG00000173039 ENSG00000185591 ENSG00000112715 PMC11810091__F7 Changes in mucosa branched N-glycosylation impacts gut microbial balance, leading to an intestinal inflammatory response ENSG00000167207 ENSG00000152127 PMC3291999__F3 MTOR signalling pathway (see text for details) ENSG00000169047 PMC5992185__F5 Ski and SnoN protein stability by the TGFB/Smad signaling pathway ENSG00000157933 ENSG00000134982 PMC8399070__F1 Nanocarriers as a Tool for the Treatment of Colorectal Cancer ENSG00000168040 ENSG00000026103 PMC5342415__F3 Meta-dimensional data integration identifies critical pathways for susceptibility, tumorigenesis and progression of endometrial cancer ENSG00000141384 ENSG00000181104 ENSG00000188784 ENSG00000143198 ENSG00000188342 ENSG00000129355 ENSG00000118971 ENSG00000122194 ENSG00000141968 ENSG00000183765 ENSG00000126218 ENSG00000112290 ENSG00000175054 ENSG00000166337 ENSG00000158786 ENSG00000078900 ENSG00000203618 ENSG00000132383 ENSG00000164344 ENSG00000171560 ENSG00000139687 ENSG00000142192 ENSG00000125651 ENSG00000081237 ENSG00000008394 ENSG00000116701 ENSG00000116157 ENSG00000102172 ENSG00000117322 ENSG00000139618 ENSG00000139219 ENSG00000100422 ENSG00000048392 ENSG00000188191 ENSG00000134057 ENSG00000198176 ENSG00000057593 ENSG00000161533 ENSG00000197299 ENSG00000164023 ENSG00000277897 ENSG00000166224 ENSG00000105127 ENSG00000131196 ENSG00000168350 PMC5706051__F7 Diagram depicting epinecidin-1-mediated degradation of MyD88a and downstream events ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC3908416__F8 Panx3 signaling pathways inhibit osteoprogenitor cell proliferation and promote cell cycle exit ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000154143 PMC3616489__F3 Emerging roles of E2Fs in cancer: an exit from cell cycle control ENSG00000135446 ENSG00000133740 ENSG00000205250 ENSG00000105810 PMC3596655__F8 Proposed molecular mechanisms of the anti-inflammatory effects of allosteric SHIP1 activation ENSG00000124102 ENSG00000010671 PMC8150642__F1 KRAS, A Prime Mediator in Pancreatic Lipid Synthesis through Extra Mitochondrial Glutamine and Citrate Metabolism ENSG00000198793 ENSG00000177606 ENSG00000136997 PMC5992185__F2 Regulation of Ski and SnoN expression by different mechanisms ENSG00000019991 ENSG00000157933 ENSG00000156574 PMC8150642__F2 KRAS, A Prime Mediator in Pancreatic Lipid Synthesis through Extra Mitochondrial Glutamine and Citrate Metabolism ENSG00000125166 ENSG00000131473 ENSG00000100325 ENSG00000115419 ENSG00000123983 ENSG00000026103 PMC5992185__F1 Regulation of the TGFB/Smad signaling pathway by Ski and SnoN ENSG00000136603 ENSG00000157933 PMC6079274__F2 JAK2 protein in intracellular crosstalk ENSG00000169047 ENSG00000198793 PMC8772740__F6 Konjac Ceramide (kCer)-Mediated Signal Transduction of the Sema3A Pathway Promotes HaCaT Keratinocyte Differentiation PMC4898659__F3 Signalling pathways modulated by NF1 ENSG00000198793 ENSG00000196712 PMC10215719__F7 Proposed mechanisms of the effect of Ptn overexpression (A) and the pharmacological inhibition of RPTPB/ζ with MY10 (B) on some of the principal signaling pathways implicated in ethanol and/or LPS acute response in adolescent mice ENSG00000105894 ENSG00000010810 ENSG00000136869 PMC5545101__F3 mTORC1 signaling and the metabolic control of cell growth ENSG00000128272 ENSG00000136997 ENSG00000084774 ENSG00000254550 PMC8533248__F2 Novel Concepts in Systemic Sclerosis Pathogenesis: Role for miRNAs ENSG00000281324 ENSG00000162337 ENSG00000198793 ENSG00000291748 ENSG00000168036 ENSG00000131724 ENSG00000108821 ENSG00000136826 PMC2562939__F1 The diphthamide modification on elongation factor-2 renders mammalian cells resistant to ricin ENSG00000154813 ENSG00000108963 PMC3656947__F3 PKC Activation Induces Inflammatory Response and Cell Death in Human Bronchial Epithelial Cells ENSG00000104856 ENSG00000104689 ENSG00000184254 ENSG00000185215 ENSG00000176597 ENSG00000144560 ENSG00000173039 ENSG00000162924 ENSG00000116514 ENSG00000166016 ENSG00000166401 ENSG00000120910 ENSG00000170961 ENSG00000281165 ENSG00000144802 ENSG00000147324 ENSG00000072786 ENSG00000006747 ENSG00000173846 ENSG00000163638 ENSG00000123689 ENSG00000189079 PMC5972910__F11 Putative role of Wnt signaling pathway during BoHV-1 latency-reactivation cycle ENSG00000117020 ENSG00000156076 ENSG00000168036 PMC11107893__F1 Molecular targets and therapeutic interventions in non-small cell lung cancer treatment ENSG00000157764 ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000047936 ENSG00000146648 ENSG00000143924 PMC7735419__F4 Image of the potential transcription factors of GPX8 ENSG00000215421 ENSG00000105392 ENSG00000177732 ENSG00000182568 ENSG00000164294 ENSG00000276561 ENSG00000196628 ENSG00000284923 ENSG00000071564 ENSG00000186777 ENSG00000215397 ENSG00000164736 ENSG00000137265 ENSG00000269404 ENSG00000113722 ENSG00000203883 ENSG00000123268 PMC9006080__F5 Molecular Signatures of Mitochondrial Complexes Involved in Alzheimer's Disease via Oxidative Phosphorylation and Retrograde Endocannabinoid Signaling Pathways ENSG00000169021 ENSG00000073578 ENSG00000117118 ENSG00000123901 ENSG00000133318 ENSG00000115310 ENSG00000004779 ENSG00000129007 ENSG00000221823 ENSG00000133019 ENSG00000164742 ENSG00000113732 ENSG00000198838 ENSG00000182240 ENSG00000188763 ENSG00000127824 ENSG00000173692 ENSG00000137267 ENSG00000163636 ENSG00000143882 PMC8435904__F5 LncRNA GAS5 Competitively Combined With miR-21 Regulates PTEN and Influences EMT of Peritoneal Mesothelial Cells via Wnt/Beta-Catenin Signaling Pathway ENSG00000168036 PMC9016245__F3 Mitochondria signaling pathways in allergic asthma ENSG00000126457 PMC7735419__F8 Proposed molecular mechanisms of GPX8 in gastric cancer cells ENSG00000134982 ENSG00000168036 ENSG00000164294 PMC6644836__F4 Partial diagram of the “Signaling by SCF-KIT” pathway showing the feedback loop that generates the “p-STAT dimers” complex annotated in Reactome ENSG00000157404 ENSG00000141968 ENSG00000179295 PMC12240780__F5 LLPS in mutant tumor suppressor genes driving carcinogenesis ENSG00000186575 ENSG00000134982 ENSG00000121067 ENSG00000168036 PMC12240780__F4 LLPS in tumorigenesis due to FOs ENSG00000196591 ENSG00000115904 PMC12240780__F3 LLPS regulates cellular phenotypes ENSG00000177169 ENSG00000123395 ENSG00000099204 PMC4633218__F7 Green Tea Extract Rich in Epigallocatechin-3-Gallate Prevents Fatty Liver by AMPK Activation via LKB1 in Mice Fed a High-Fat Diet ENSG00000285070 ENSG00000096717 ENSG00000026103 PMC7910492__F8 Mechanism for the synergistic effects of BKM120 and olaparib on the death of MDA-MB-231 cells ENSG00000143799 ENSG00000012048 ENSG00000150907 ENSG00000291803 ENSG00000051180 ENSG00000138385 ENSG00000139618 PMC11921546__F2 LPS-TLR4 mediated signal transduction pathway ENSG00000092439 ENSG00000183735 ENSG00000170458 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC5256158__F5 Schematics of multitargeted actions of T1AM on metabolic and steroidogenic pathways ENSG00000042832 ENSG00000122966 ENSG00000172005 ENSG00000198911 ENSG00000132170 ENSG00000026103 PMC6053305__F10 PERK signaling pathway in modulating skeletal phenotype ENSG00000128272 ENSG00000125398 ENSG00000105550 PMC139401__F2 TLR signal transduction pathways ENSG00000115415 ENSG00000125538 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC6407245__F1 Nongenomic and Genomic actions of Thyroid hormone and thyroid hormone receptor ENSG00000151376 ENSG00000291971 ENSG00000198793 ENSG00000168610 PMC8449055__F2 New strategies for targeting kinase networks in cancer ENSG00000167601 ENSG00000157764 ENSG00000146648 PMC2820927__F3 Model illustrating the dynamic overlapping phases of early events of KSHV infection in endothelial and fibroblast cells and KSHV-induced signal pathways and their role in infection ENSG00000291971 ENSG00000163914 PMC3215943__F4 MOLECULAR MECHANISMS OF FEAR LEARNING AND MEMORY ENSG00000174576 ENSG00000198793 ENSG00000198576 PMC2875805__F10 Cartoon illustrates genomic and nongenomic actions of VDR signaling in inhibition of human CYP7A1 gene transcription in human hepatocytes ENSG00000291971 PMC3215943__F3 MOLECULAR MECHANISMS OF FEAR LEARNING AND MEMORY ENSG00000198793 ENSG00000198576 PMC6537015__F8 The proposed mechanism underlying TRPA1-mediated CMF transdifferentiation and cardiac fibrosis after MI injury ENSG00000104321 ENSG00000133110 PMC5045229__F4 Cabozantinib provides dual inhibition of MET and VEGFR2 preventing the MET pathway from acting as an alternative pathway in the development of VEGF TKI resistance ENSG00000019991 ENSG00000002330 ENSG00000198793 PMC2219551__F7 Signaling Pathway Involved in Neutrophil Elastase–Stimulated MUC1 Transcription ENSG00000291363 ENSG00000137857 ENSG00000163235 ENSG00000185591 ENSG00000146648 PMC8413298__F9 Many gCIS function on the same pathway as the oncogenic driver responsible for tumor initiation ENSG00000019991 ENSG00000033327 ENSG00000005339 ENSG00000104517 ENSG00000160999 ENSG00000131023 ENSG00000151348 ENSG00000281766 ENSG00000178188 ENSG00000171150 ENSG00000111837 ENSG00000128052 ENSG00000026508 ENSG00000122779 PMC5795421__F2 Human micro RNA (miRNA) pathway ENSG00000128191 ENSG00000113360 PMC2713330__F1 Innate Immunity in the Lungs ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC8097099__F1 SUMOylation Wrestles With the Occurrence and Development of Breast Cancer ENSG00000142230 ENSG00000153201 ENSG00000116030 ENSG00000188612 ENSG00000184900 PMC4338202__F5 Whole Transcriptome Analysis Using Next-Generation Sequencing of Sterile-Cultured Eisenia andrei for Immune System Research ENSG00000172936 ENSG00000150455 ENSG00000184216 PMC4499885__F5 Homoharringtonine induces apoptosis and inhibits STAT3 via IL-6/JAK1/STAT3 signal pathway in Gefitinib-resistant lung cancer cells ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC7012612__F4 IGF1 signaling pathway is under increased evolutionary constraint in long-lived, large-bodied mammals ENSG00000124102 ENSG00000140992 ENSG00000002330 ENSG00000291971 ENSG00000169047 ENSG00000115904 ENSG00000099942 ENSG00000196396 ENSG00000089159 ENSG00000160691 ENSG00000179295 ENSG00000067606 ENSG00000163914 ENSG00000106070 ENSG00000071051 ENSG00000184304 ENSG00000140443 PMC4083591__F1 Type I Interferon in the Pathogenesis of Lupus ENSG00000138378 ENSG00000164430 ENSG00000105397 ENSG00000118503 ENSG00000166278 ENSG00000276561 ENSG00000184216 ENSG00000057663 PMC7142266__F3 Functional domains of BRCA1/2 protein with pathogenic mutations ENSG00000149311 ENSG00000012048 ENSG00000136492 ENSG00000108384 ENSG00000099194 ENSG00000139618 PMC7142266__F2 Mechanisms of tumorigenesis attributable to FA mutations ENSG00000012048 ENSG00000175054 ENSG00000144554 ENSG00000115392 ENSG00000187741 ENSG00000112039 ENSG00000158169 ENSG00000149554 PMC8171373__F1 Hijacking the Pathway: Perspectives in the Treatment of Mature T-cell Leukemias ENSG00000149311 ENSG00000113263 ENSG00000171791 PMC5589605__F4 Systematic analysis of coronary artery disease datasets revealed the potential biomarker and treatment target ENSG00000071564 ENSG00000245848 ENSG00000110203 ENSG00000118520 ENSG00000280908 PMC6467965__F2 Schematic presentation of the cytotoxic pathways, induced in cancer cells by the complement C5b-9, the counteractive cellular resistance mechanisms, and postulated approaches to overcome this cancer evasion ENSG00000196352 ENSG00000117335 ENSG00000168404 ENSG00000285379 PMC8107084__F6 MiR‐155 promotes colitis‐associated intestinal fibrosis by targeting HBP1/Wnt/B‐catenin signalling pathway ENSG00000134982 ENSG00000168036 PMC5882217__F3 Hippo pathway and cross-talk with other signaling pathways in mammals ENSG00000087095 ENSG00000126016 ENSG00000186575 ENSG00000147162 ENSG00000109321 ENSG00000134982 ENSG00000144560 ENSG00000163914 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC5133786__F1 Proteolytic processing of the amyloid precursor protein (APP) and its modulation by vitamins A, D, E, and K ENSG00000142192 ENSG00000205221 ENSG00000168615 ENSG00000119912 PMC3829599__F1 mTOR pathway signaling cascade ENSG00000102034 ENSG00000106070 ENSG00000169047 PMC6997601__F2 MVA pathway and the synthesis of astaxanthin and ergosterol in X ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC6743006__F3 Exposure to high fat diets over time, enriched in saturated fatty acids, would promote the glial activation and an increased mitochondrial oxidative stress ENSG00000142192 ENSG00000169047 PMC3277712__F1 Importance of cytokine signalling for CD4+ T-cell differentiation ENSG00000107485 ENSG00000049768 PMC3899195__F6 ZNF365 promotes stalled replication forks recovery to maintain genome stability ENSG00000134982 ENSG00000117399 PMC8844036__F8 Schematic diagram of sEVs DNAJB8 based signaling pathway in CRC L-OHP resistance ENSG00000184207 PMC7842149__F3 Angiotensin II and T lymphocytes activation during COVID-19 best scenario ENSG00000184012 PMC9562224__F11 HOCI Probe CPP Induces the Differentiation of Human Dermal Fibroblasts into Vascular Endothelial Cells through PHD2/HIF-1A/HEY1 Signaling Pathway ENSG00000110799 ENSG00000128052 PMC11951404__F1 Transcriptional and posttranslational regulation of CONSTANS (CO) CO acts as the core regulator of the photoperiod response pathway to integrate external and internal signals into the photoperiodic flowering pathway PMC7842149__F1 Roles of the RAAS in health and COVID-19: A better and worse scenarios—(A) Basal angiotensin system ENSG00000130234 ENSG00000184012 ENSG00000154016 PMC4384112__F3 IFN-induced signaling through the JAK-STAT pathway ENSG00000213928 ENSG00000105397 ENSG00000033800 ENSG00000142166 PMC9773994__F3 Edible plant extracellular vesicles: An emerging tool for bioactives delivery PMC10215861__F3 Roles of RONSs during skeletal muscle pathologies ENSG00000177169 ENSG00000169047 ENSG00000198793 ENSG00000198947 PMC10975450__F2 Signaling pathway molecular mechanisms: Several signaling pathways play a major role in tissue development and thus in PSC differentiation, specifically into cardiac tissue ENSG00000281324 ENSG00000117425 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000169047 ENSG00000156574 ENSG00000168036 ENSG00000150457 ENSG00000131023 ENSG00000160691 ENSG00000170365 ENSG00000117525 ENSG00000106571 ENSG00000150907 ENSG00000139549 ENSG00000164690 ENSG00000128602 ENSG00000163501 PMC6638919__F10 NADPH oxidase 4 mediates TGFB1/Smad signaling pathway induced acute kidney injury in hypoxia ENSG00000086991 PMC2702690__F9 Molecular Mechanisms of HIF-1A Modulation Induced by Oxygen Tension and BMP2 in Glioblastoma Derived Cells ENSG00000198793 ENSG00000168610 PMC3690774__F5 Global gene expression analysis reveals pathway differences between teratogenic and non-teratogenic exposure concentrations of bisphenol A and 17Beta-estradiol in embryonic zebrafish ENSG00000138002 ENSG00000115718 ENSG00000128602 ENSG00000196689 ENSG00000172238 PMC5925819__F2 CDP-DAG and Kennedy pathways ENSG00000163624 ENSG00000101290 PMC10341943__F3 Role of the Notch pathway in cell-fate decisions in the somite ENSG00000138136 ENSG00000261371 ENSG00000135903 PMC7477297__F3 Hypothetical OT signaling pathways targeting the nucleus and mitochondria in the cardiac cells ENSG00000285109 ENSG00000167658 ENSG00000096088 ENSG00000168610 ENSG00000081189 PMC8299209__F2 Pathophysiological and tissue regenerative functions of MSCs mediated via the WNT signaling pathway ENSG00000087095 ENSG00000169071 ENSG00000010810 ENSG00000168036 ENSG00000168610 PMC8299209__F1 Pathophysiological and tissue regenerative functions of MSCs mediated via the WNT signaling pathway ENSG00000134982 ENSG00000168036 PMC5562273__F2 A simple answer to complex questions: C. elegans as an experimental model for examining the DNA damage response and disease genes ENSG00000012061 ENSG00000167986 ENSG00000136936 PMC4172058__F1 Schematic diagram depicting the most representative signaling of the PI3K/AKT pathway ENSG00000002330 ENSG00000198793 ENSG00000164327 PMC6269490__F1 Roles of CO in metabolic homeostasis ENSG00000128272 ENSG00000144895 ENSG00000105550 ENSG00000285069 PMC3177572__F6 Schematic diagram summarizing the bidirectional role of PIAS1 in regulating JNK-dependent oxidative stress responses ENSG00000079387 ENSG00000033800 ENSG00000116030 PMC8299209__F3 Pathophysiological and tissue regenerative functions of MSCs mediated via the WNT signaling pathway ENSG00000087095 ENSG00000125538 ENSG00000177606 ENSG00000168036 ENSG00000157625 ENSG00000131323 ENSG00000175104 PMC9578543__F8 Enhanced Apoptosis in Choroidal Tissues in Lens-Induced Myopia Guinea Pigs by Activating the RASA1 Signaling Pathway ENSG00000002330 PMC4368378__F1 PINK1-Parkin signalling ENSG00000135655 ENSG00000158828 ENSG00000247077 ENSG00000135093 PMC7222508__F6 Network of 145 candidate genes with main drug metabolism pathway genes ENSG00000151490 ENSG00000064601 ENSG00000171444 ENSG00000134982 ENSG00000198793 ENSG00000160710 ENSG00000196498 ENSG00000073921 ENSG00000100485 ENSG00000113360 PMC10343931__F4 Possible mechanisms by which exercise upregulates NAD+ to improve mitochondrial autophagy ENSG00000157064 ENSG00000122696 ENSG00000096717 ENSG00000164087 PMC6913091__F3 Pushing the envelope: LPS modifications and their consequences ENSG00000172936 ENSG00000136869 ENSG00000076641 PMC5778108__F1 Canonical and non-canonical NFKB signaling in humans ENSG00000104856 ENSG00000186716 ENSG00000173039 ENSG00000111321 PMC8417591__F2 Extracellular Vesicles in Sickle Cell Disease: Plasma Concentration, Blood Cell Types Origin Distribution and Biological Properties ENSG00000162711 ENSG00000136869 ENSG00000162692 PMC4439968__F1 Toll-like receptor 4 signaling pathway ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC6684943__F1 Regulation of C/EBPB in MDSCs ENSG00000172216 ENSG00000118520 ENSG00000007171 PMC8540846__F1 Molecular Targets and Promising Therapeutics of Triple-Negative Breast Cancer ENSG00000012048 ENSG00000083093 ENSG00000117525 ENSG00000120875 ENSG00000198793 ENSG00000146648 ENSG00000139618 PMC3690116__F1 Schematic model of FGF-2 and FGF-18 signaling pathways in articular cartilage and IVD ENSG00000132478 ENSG00000077782 PMC2841329__F1 Model for the role of ΔNp73B in the DDR ENSG00000188486 ENSG00000149311 PMC4354324__F3 Multiple promising targets for regulating cancer metabolism ENSG00000131473 ENSG00000065833 ENSG00000169710 PMC2781055__F3 Ingenuity pathway analysis (IPA) of microarray data generated several genetic networks ENSG00000142192 ENSG00000284774 ENSG00000164128 ENSG00000112964 ENSG00000065361 ENSG00000134363 ENSG00000132478 ENSG00000170498 ENSG00000169032 ENSG00000143226 ENSG00000131096 ENSG00000121807 ENSG00000168610 ENSG00000105954 ENSG00000121966 ENSG00000183395 ENSG00000178188 ENSG00000170893 ENSG00000136160 ENSG00000115009 PMC11546116__F3 Vascular regeneration after MI ENSG00000178860 ENSG00000128917 ENSG00000148400 PMC11546116__F2 Regulatory mechanisms involved in myocardial regeneration ENSG00000178860 ENSG00000135446 ENSG00000168036 ENSG00000123374 ENSG00000205250 ENSG00000164532 ENSG00000282899 ENSG00000178568 PMC2732336__F1 Outline of the major cell surface receptor-mediated signaling pathways important in the differentiation, survival, and function of melanocytes ENSG00000002330 ENSG00000170558 ENSG00000198793 ENSG00000168036 PMC4630409__F1 Schematic overview of TLR and NLR signaling pathways ENSG00000239732 ENSG00000167207 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000276561 ENSG00000164342 PMC4659591__F10 MicroRNA Profiling Implies New Markers of Gemcitabine Chemoresistance in Mutant p53 Pancreatic Ductal Adenocarcinoma ENSG00000002330 ENSG00000135446 ENSG00000136997 ENSG00000123374 ENSG00000105810 ENSG00000140443 PMC10985960__F10 Hypothesis of possible IFN-I signaling pathway regulatory mechanism based on our findings in PD ENSG00000213928 PMC9027317__F10 Fucoxanthin Attenuates Free Fatty Acid-Induced Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism/Oxidative Stress/Inflammation via the AMPK/Nrf2/TLR4 Signaling Pathway ENSG00000172936 ENSG00000136869 ENSG00000079999 ENSG00000026103 PMC4379939__F1 As yet unknown side of DC secretion post-TLR activation, and trafficking molecules currently identified in DC function ENSG00000265808 ENSG00000172005 ENSG00000103769 ENSG00000172936 ENSG00000175104 ENSG00000118640 PMC3101238__F7 Omeprazole Inhibits Proliferation and Modulates Autophagy in Pancreatic Cancer Cells ENSG00000130021 ENSG00000173599 ENSG00000254550 PMC9334696__F2 Biopolymeric nanoparticles based effective delivery of bioactive compounds toward the sustainable development of anticancerous therapeutics ENSG00000163914 PMC6080592__F3 Developments in toxicogenomics: understanding and predicting compound-induced toxicity from gene expression data ENSG00000051523 ENSG00000138798 ENSG00000181104 ENSG00000167083 ENSG00000100033 ENSG00000092820 ENSG00000178726 ENSG00000141968 ENSG00000104368 ENSG00000182541 ENSG00000173369 ENSG00000213949 ENSG00000166501 ENSG00000036473 ENSG00000023445 ENSG00000087245 ENSG00000259207 ENSG00000005961 ENSG00000063854 ENSG00000145384 ENSG00000231925 ENSG00000291983 ENSG00000127445 ENSG00000019582 ENSG00000281614 ENSG00000250799 ENSG00000161921 ENSG00000010810 ENSG00000163131 ENSG00000134853 ENSG00000291748 ENSG00000175899 PMC9123807__F1 Repurposing of cyclophilin A inhibitors as broad-spectrum antiviral agents ENSG00000187608 ENSG00000125347 PMC9693393__F2 DNA Damage Stress Response and Follicle Activation: Signaling Routes of Mammalian Ovarian Reserve ENSG00000149311 ENSG00000175054 ENSG00000104899 ENSG00000198793 PMC5384128__F1 Adaptive resistance and innate resistance ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC7257252__F5 Fibroblast Growth Factor–21 ameliorates hepatic encephalopathy by activating the STAT3-SOCS3 pathway to inhibit activated hepatic stellate cells ENSG00000105550 ENSG00000138798 ENSG00000168610 PMC4963952__F5 Regulation of genes of Cell Cycle pathway during senescence induction in HFF strains ENSG00000108055 ENSG00000091651 ENSG00000145386 ENSG00000166851 ENSG00000117399 ENSG00000093009 ENSG00000094804 ENSG00000116670 ENSG00000156970 ENSG00000134057 ENSG00000132646 ENSG00000172005 ENSG00000123374 ENSG00000149554 ENSG00000112742 ENSG00000080839 ENSG00000253729 PMC5653149__F15 Regulation of Cellular Redox Signaling by Matricellular Proteins in Vascular Biology, Immunology, and Cancer ENSG00000176463 ENSG00000265972 ENSG00000168938 ENSG00000205220 ENSG00000073756 ENSG00000007171 PMC11604586__F1 Progress and perspectives on BMP9-ID1 activation of HIF-1A and VEGFA to promote angiogenesis in hepatic alveolar echinococcosis ENSG00000198793 ENSG00000061273 ENSG00000112715 ENSG00000125968 PMC9693393__F1 DNA Damage Stress Response and Follicle Activation: Signaling Routes of Mammalian Ovarian Reserve ENSG00000157404 ENSG00000086730 PMC4963952__F6 Regulation of genes of cell cycle pathway during senescence induction in MRC-5 strains ENSG00000112118 ENSG00000091651 ENSG00000073111 ENSG00000277273 ENSG00000076003 ENSG00000117399 ENSG00000276876 ENSG00000146670 ENSG00000122375 ENSG00000132646 ENSG00000136997 ENSG00000115942 ENSG00000130222 ENSG00000123374 ENSG00000112742 ENSG00000282899 PMC7884039__F12 Molecular mechanism of p75NTR in regulating age‐associated changes in the homeostatic of synaptic plasticity ENSG00000106683 ENSG00000198576 PMC5974538__F1 Occurrence of plant photodynamic stress ENSG00000144410 ENSG00000066926 ENSG00000126088 ENSG00000188690 PMC4075272__F2 Signaling pathways altered by MVNP and mutant p62 ENSG00000120656 ENSG00000096717 ENSG00000175104 PMC3091694__F6 Toll-like Receptor signalling canonical pathway ENSG00000170458 ENSG00000150455 PMC5578405__F10 Schematic summary of the possible link between IGF-1R signaling, synaptic changes, neurotransmitter function and inflammatory response ENSG00000198793 ENSG00000189403 ENSG00000136869 ENSG00000140443 PMC8555850__F1 Bile acid regulation ENSG00000160867 ENSG00000167910 ENSG00000180432 ENSG00000099377 ENSG00000115271 ENSG00000135929 PMC6973012__F1 Molecular mechanisms in allergic inflammation ENSG00000137033 ENSG00000197971 ENSG00000105656 ENSG00000145777 ENSG00000166090 PMC6701793__F2 Biological processes associated with up-regulated genes after cecal ligation and puncture and back-regulated by landiolol infusion ENSG00000071246 ENSG00000198755 ENSG00000142330 ENSG00000123454 ENSG00000138185 ENSG00000101558 ENSG00000073536 ENSG00000164938 ENSG00000158825 ENSG00000170893 ENSG00000288297 ENSG00000095794 ENSG00000275544 ENSG00000162889 ENSG00000148346 ENSG00000178035 ENSG00000142192 ENSG00000115163 ENSG00000102900 ENSG00000008513 ENSG00000109320 ENSG00000173598 ENSG00000136938 ENSG00000198929 ENSG00000168610 ENSG00000160691 ENSG00000100422 ENSG00000185652 ENSG00000127080 ENSG00000100596 ENSG00000145192 ENSG00000168297 ENSG00000213699 ENSG00000175899 ENSG00000075420 ENSG00000136160 ENSG00000085871 PMC9234285__F3 Biological Characteristics of HLA-G and Its Role in Solid Organ Transplantation ENSG00000186810 ENSG00000276051 ENSG00000121807 PMC11671501__F3 Apoptotic caspase-mediated pyroptosis PMC8027873__F2 STRING diagram representing protein interaction pathway derived from the 77 proteins quantified in at least 80% of OCT and in none FFPE samples ENSG00000156642 ENSG00000084073 ENSG00000073712 ENSG00000091140 PMC7142266__F1 Schematic elucidation of the FA pathway mechanism used during DNA repair ENSG00000012061 ENSG00000175054 ENSG00000083093 ENSG00000188827 ENSG00000162607 ENSG00000276787 PMC3111844__F1 Overview of Androgen Metabolism Pathway Genes Considered, Including Candidate Genes and Genetic Variants Studied ENSG00000277893 ENSG00000143375 PMC6912814__F1 Summary of the main mentioned markers of the autophagy-lysosomal pathway (ALP) ENSG00000005893 ENSG00000158828 PMC8281110__F6 M6A in osteoporosis, arthritis and osteosarcoma (Review) ENSG00000138795 ENSG00000156802 ENSG00000198492 ENSG00000168036 ENSG00000091542 ENSG00000185721 ENSG00000165819 PMC4404310__F1 Proposed schema of aberrant signal transduction mediated by the TSLPR heterodimer in CRLF2-overexpressing ALL ENSG00000198793 ENSG00000145777 PMC8281110__F3 M6A in osteoporosis, arthritis and osteosarcoma (Review) ENSG00000178860 ENSG00000245848 ENSG00000135414 ENSG00000172936 ENSG00000174197 ENSG00000175104 ENSG00000165819 PMC5879898__F6 MAPK signaling pathway and the JAK-ATAT signaling pathway ENSG00000142192 ENSG00000137193 ENSG00000146648 PMC9428757__F5 Thioredoxin-interacting protein: A new therapeutic target in bone metabolism disorders? ENSG00000278718 ENSG00000162711 ENSG00000265972 PMC8762245__F2 Exosomes Regulate NLRP3 Inflammasome in Diseases ENSG00000178860 ENSG00000162711 ENSG00000011198 PMC7250321__F9 EV71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS accumulation ENSG00000178573 ENSG00000161533 ENSG00000156273 PMC6983994__F4 This study showed that after 24 hours of treatment with YM155, the miR-9 expression levels increased significantly compared to control cells; in addition, the expression of two target genes, including MDR1 and SIRT1, decreased significantly ENSG00000169554 ENSG00000171791 ENSG00000096717 PMC2788021__F3 A model for torpor induction in mammals that links reduced availability of food in the environment with the energy status of the cell, the mammalian circadian clock, and response to oxidative stress ENSG00000105835 ENSG00000096717 PMC3982918__F1 Notch signaling pathway and agents in clinical development ENSG00000112576 ENSG00000140564 ENSG00000128917 ENSG00000136997 ENSG00000184916 ENSG00000090932 PMC8891342__F1 Impact of intracellular innate immune receptors on immunometabolism ENSG00000157184 ENSG00000160883 ENSG00000136872 ENSG00000159399 PMC5366816__F2 Drug targets in AR signaling pathway ENSG00000198793 ENSG00000146648 PMC7078111__F1 HGF/c-Met signaling and lncRNA/miRNA/c-Met interaction ENSG00000019991 ENSG00000198793 PMC6881418__F3 Roles of CAFs in drug resistance ENSG00000145431 ENSG00000019991 ENSG00000107562 ENSG00000151778 PMC8455403__F7 Increased uterine androgen receptor protein abundance results in implantation and mitochondrial defects in pregnant rats with hyperandrogenism and insulin resistance ENSG00000005073 ENSG00000082175 ENSG00000118785 ENSG00000113070 ENSG00000146678 ENSG00000106459 PMC9166529__F2 Characteristics of the cancer stem cell niche and therapeutic strategies ENSG00000198793 PMC8849249__F2 Low Bone Mineral Density in Hemophiliacs ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC7705238__F1 IL-23/IL-17 signaling transduction ENSG00000162594 ENSG00000131323 ENSG00000127191 ENSG00000168610 ENSG00000163702 ENSG00000076604 PMC4888770__F1 Radiation induced activation of canonical and non-canonical hedgehog (Hh) signaling pathway ENSG00000164161 ENSG00000128602 PMC9166529__F4 Characteristics of the cancer stem cell niche and therapeutic strategies ENSG00000134982 ENSG00000168036 ENSG00000128602 PMC4503712__F3 Candida albicans proteins for metabolic pathway ENSG00000146701 PMC7705238__F2 T-cell immune axis and associated cytokines in the pathogenesis of psoriasis, hidradenitis suppurativa, atopic dermatitis, and alopecia areata ENSG00000162711 ENSG00000143546 ENSG00000163220 ENSG00000143556 ENSG00000143631 ENSG00000115009 ENSG00000112486 PMC8208619__F6 CXCR4 blockade sensitizes osteosarcoma to doxorubicin by inducing autophagic cell death via PI3K-Akt-mTOR pathway inhibition ENSG00000090402 ENSG00000198793 ENSG00000121966 PMC9254464__F7 Repurposing Oxiconazole against Colorectal Cancer via PRDX2-mediated Autophagy Arrest ENSG00000198793 PMC3379883__F2 Leptin and the CNS Control of Glucose Metabolism ENSG00000168610 PMC8998760__F1 Interplay between PARP Inhibitors and Immunotherapy in Ovarian Cancer: The Rationale behind a New Combination Therapy ENSG00000164430 PMC3045854__F1 Memory genes identified in model systems overlap with genes identified in human mental retardation ENSG00000163235 ENSG00000138798 ENSG00000198793 ENSG00000163914 ENSG00000079482 ENSG00000196712 PMC7564838__F1 The metabolic pathway for MA biosynthesis in E ENSG00000128602 ENSG00000062485 PMC9163322__F1 Novel Immune Checkpoints in Esophageal Cancer: From Biomarkers to Therapeutic Targets ENSG00000089692 ENSG00000181847 PMC7653260__F4 Signalling pathway of programmed necrosis in hearing loss ENSG00000102871 ENSG00000168040 ENSG00000168404 PMC7653260__F3 Signalling pathway of autophagy in HL ENSG00000177169 ENSG00000198793 ENSG00000145782 PMC8345080__F1 Osteopontin as a Regulator of Colorectal Cancer Progression and Its Clinical Applications ENSG00000170365 ENSG00000151376 ENSG00000138795 ENSG00000134982 ENSG00000168036 ENSG00000152592 ENSG00000152591 ENSG00000204217 ENSG00000196628 PMC2702150__F3 FIBROTIC DISEASE AND THE TH1/TH2 PARADIGM ENSG00000135218 ENSG00000131724 ENSG00000100985 ENSG00000122194 ENSG00000007171 PMC8479066__F6 Receptor tyrosine kinase ROR1 ameliorates AB1–42 induced cytoskeletal instability and is regulated by the miR146a-NEAT1 nexus in Alzheimer’s disease PMC6940991__F3 Mutant p53 GOF and hypoxia ENSG00000094631 PMC6940991__F2 Mutant p53 gain of function (GOF) in metabolism and invasion ENSG00000138764 ENSG00000134057 ENSG00000168610 PMC7753939__F5 Top significantly related pathways of “herb-ingredient-target” networks in JZD against NAFLD: (a) nuclear receptor transcription pathway; (b) regulation of lipid metabolic process ENSG00000180210 ENSG00000066468 ENSG00000189171 ENSG00000164399 ENSG00000136869 ENSG00000132170 PMC6906418__F1 Intracellular sensing of viral genomes and viral evasion ENSG00000094631 ENSG00000135655 ENSG00000109332 ENSG00000112343 ENSG00000101782 ENSG00000204977 ENSG00000146833 ENSG00000141569 ENSG00000183735 ENSG00000088888 ENSG00000140455 ENSG00000067248 ENSG00000164068 ENSG00000143258 ENSG00000109670 ENSG00000133874 ENSG00000176624 ENSG00000276561 ENSG00000101695 ENSG00000101557 ENSG00000138378 ENSG00000175489 ENSG00000131323 ENSG00000083799 ENSG00000247315 ENSG00000121060 ENSG00000138385 PMC3820944__F6 Representative Tyr phosphorylation sites affected by erlotinib in the EGFR and ErbB2 canonical pathways ENSG00000185634 ENSG00000065361 ENSG00000291971 ENSG00000165458 ENSG00000105647 ENSG00000124181 ENSG00000160293 ENSG00000146648 ENSG00000105723 ENSG00000089159 ENSG00000160691 ENSG00000179295 PMC5899637__F1 Drug resistance in HER2-positive breast cancer brain metastases: blame the barrier or the brain? PMC10635689__F8 BJ-5ta Exo exert a protective effect against UVB-induced photoaging ENSG00000105329 ENSG00000051180 PMC7295987__F4 Outline of the signaling pathways activated by CpG ENSG00000177455 ENSG00000140992 ENSG00000239732 ENSG00000170458 ENSG00000172936 ENSG00000184216 PMC6412245__F9 Schematic diagram shows the therapeutic effects of ergosterol on diabetic nephropathy ENSG00000132646 PMC6906418__F2 Intracellular sensing of viral genomes and viral evasion ENSG00000106785 ENSG00000146063 ENSG00000112343 ENSG00000169871 ENSG00000276561 ENSG00000163904 ENSG00000171720 ENSG00000164430 ENSG00000135114 ENSG00000135912 ENSG00000138468 ENSG00000170703 ENSG00000138942 ENSG00000247315 PMC11771162__F3 Statins exhibit pro-angiogenic properties ENSG00000163914 PMC6825561__F1 Proposed scenario of current strategies targeting different traits of dysfunctional mitochondria in Alzheimer disease (AD), including mitochondrial bioenergetics and mitochondrial homeostasis ENSG00000177169 ENSG00000142192 ENSG00000083290 ENSG00000198793 ENSG00000096717 ENSG00000106459 PMC3538421__F3 Summary of P450 enzymes in cholesterol and bile acid biosynthesis ENSG00000001630 ENSG00000167910 ENSG00000036530 ENSG00000180432 ENSG00000135929 PMC11998530__F8 Abortive PDCoV infection triggers Wnt/Beta-catenin pathway activation, enhancing intestinal stem cell self-renewal and promoting chicken resistance ENSG00000134982 ENSG00000168036 PMC11432203__F7 Causality of CD4+ TEM markers and PTB and COVID-19 infection based on MR analysis (by Figdraw 2 ENSG00000089692 PMC8116604__F4 Evolving landscape of N6-methyladenosine modification in the tumor microenvironment ENSG00000145388 ENSG00000037897 ENSG00000128272 ENSG00000173599 ENSG00000136997 ENSG00000145321 ENSG00000040199 ENSG00000091542 ENSG00000165819 PMC3397898__F6 Signaling pathways that regulate cAMP-mediated WPB exocytosis ENSG00000006451 PMC4863711__F2 An overview of different signaling pathways activated by high glucose ambience, which leads to an altered expression of various ECM glycoproteins, and of genes relevant to EMT and apoptosis processes ENSG00000143546 ENSG00000134982 ENSG00000198793 ENSG00000167658 ENSG00000168036 ENSG00000172936 ENSG00000136869 PMC3538421__F5 Diagram showing the fundamental steps and P450 enzymes involved in vitamin D biosynthesis and degradation pathway ENSG00000111012 ENSG00000019186 ENSG00000186104 PMC3634798__F1 Stress response pathways ENSG00000181019 ENSG00000005421 ENSG00000130649 ENSG00000171759 ENSG00000140465 ENSG00000106546 PMC8728107__F2 Neural regulations of the tumor microenvironment ENSG00000132329 ENSG00000291971 ENSG00000064989 PMC3717064__F1 NK cell activating and inhibitory receptors and their downstream signaling molecules ENSG00000167613 ENSG00000291603 ENSG00000213658 ENSG00000010810 ENSG00000104972 ENSG00000173599 PMC8728107__F1 Neural regulations of the tumor microenvironment ENSG00000102145 ENSG00000291971 ENSG00000168610 PMC8891342__F3 Impact of intracellular innate immune receptors on immunometabolism ENSG00000111537 ENSG00000163568 ENSG00000150907 ENSG00000198793 ENSG00000160703 ENSG00000049768 ENSG00000175104 PMC8027849__F1 Resistance to CDK4/6 inhibitors ENSG00000083857 ENSG00000019991 ENSG00000135446 ENSG00000198793 ENSG00000136997 ENSG00000121067 ENSG00000123374 ENSG00000105810 ENSG00000151876 ENSG00000077782 ENSG00000168610 ENSG00000131023 PMC9316979__F7 Transcriptome Analysis Reveals Key Gene Expression Changes in Blue Catfish Sperm in Response to Cryopreservation ENSG00000188486 ENSG00000110711 ENSG00000162711 ENSG00000124256 ENSG00000213928 ENSG00000002330 ENSG00000099985 ENSG00000168040 ENSG00000164305 ENSG00000149311 ENSG00000150782 ENSG00000148798 ENSG00000083799 ENSG00000168404 ENSG00000285379 ENSG00000143258 ENSG00000164342 ENSG00000084774 ENSG00000062485 PMC8989532__F8 RNA polymerase pausing, stalling and bypass during transcription of damaged DNA: from molecular basis to functional consequences ENSG00000163914 ENSG00000135605 PMC2889604__F7 The regulation of neuronal migration and neurite outgrowth by the MRTF/Srf pathway ENSG00000149269 ENSG00000163914 PMC4123481__F3 Role of STAT1 and STAT3 in Foxp3 expression and cytokine production in Tregs ENSG00000111537 ENSG00000115415 ENSG00000049768 ENSG00000168610 PMC5615630__F7 RSV inhibiting NKTCL cells ENSG00000149311 ENSG00000002330 ENSG00000168610 PMC4498148__F1 WNT pathway is significantly upregulated in invasive mutant TP53 cells ENSG00000095739 ENSG00000149968 ENSG00000196549 ENSG00000108688 ENSG00000168036 ENSG00000150764 ENSG00000099194 ENSG00000145386 ENSG00000283060 ENSG00000118971 ENSG00000125084 ENSG00000171345 PMC12018449__F1 AS-IV in the pathogenesis of arrhythmia ENSG00000162711 ENSG00000178573 ENSG00000136869 ENSG00000079999 PMC6795678__F1 Scheme of the parietal cell of a gastric gland ENSG00000036828 PMC9131857__F9 Peste Des Petits Ruminants Virus N Protein Is a Critical Proinflammation Factor That Promotes MyD88 and NLRP3 Complex Assembly ENSG00000162711 ENSG00000172936 ENSG00000175104 PMC22753__F6 A signal transduction pathway leading to the phosphorylation and activation of mTOR in response to insulin ENSG00000005882 ENSG00000198793 PMC7053123__F4 Gemcitabine resistance and metabolism ENSG00000105835 ENSG00000198793 ENSG00000171848 ENSG00000169710 ENSG00000168610 ENSG00000086730 PMC6541752__F1 Comparison of nucleic acid signalling pathways leading to type I interferon (IFN) production in an autoimmune disease and bacterial infection ENSG00000183735 ENSG00000164430 ENSG00000167207 ENSG00000136869 PMC5374984__F1 The autophagy pathway ENSG00000177169 ENSG00000110497 ENSG00000198793 PMC3042782__F2 Models for HJV cleavage by furin-like activity and matriptase-2 ENSG00000140564 PMC9312358__F4 Oxidative Stress in the Pathogenesis of Atherothrombotic Diseases ENSG00000148400 ENSG00000162692 ENSG00000096717 ENSG00000114315 ENSG00000142082 PMC6896241__F1 Representation of causal interaction data in a standardized format ENSG00000166813 ENSG00000136997 ENSG00000128602 PMC8998102__F3 Pyroptosis and Sarcopenia: Frontier Perspective of Disease Mechanism ENSG00000278718 ENSG00000162711 ENSG00000150782 PMC3857153__F8 Transcriptome profiling and genome-wide DNA binding define the differential role of fenretinide and all-trans RA in regulating the death and survival of human hepatocellular carcinoma Huh7 cells ENSG00000023445 ENSG00000120833 ENSG00000157764 ENSG00000118503 ENSG00000127191 ENSG00000169174 PMC3157269__F3 Sensing the HP-PRRSV infection by host cell ENSG00000115415 ENSG00000123609 ENSG00000172936 ENSG00000276561 ENSG00000164342 ENSG00000278788 PMC10181252__F1 Wnt/Beta-catenin signaling pathway in tumor progression ENSG00000134982 ENSG00000168036 PMC11172503__F2 Anti-senescence effect and molecular mechanisms of royal jelly (RJ) and its components on cellular senescence, healthy aging, and longevity induced by endogenous and exogenous factors ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC4926373__F1 Schematic overview of DNA damaging agents, radiotherapy, DNA damage, the cellular response upon DNA damage, genetic variation, epigenetic regulation and cancer therapy response ENSG00000143799 ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000051180 PMC6791057__F2 Mechanisms underlying the sex-specific establishment of the Wolffian duct ENSG00000066468 ENSG00000244405 ENSG00000138798 ENSG00000175832 ENSG00000077782 ENSG00000146648 PMC11172503__F1 Nrf2 and NFKB signaling pathways by royal jelly (RJ) ENSG00000087245 ENSG00000181019 ENSG00000178573 ENSG00000100985 PMC10439834__F1 IL-17 signaling pathway: transduction and amplification ENSG00000082512 ENSG00000127191 ENSG00000076604 PMC10181252__F2 Various flavonoids on the Wnt/Beta-catenin pathway ENSG00000134982 ENSG00000168036 PMC4979424__F8 Proposed model of VacA effects on Cx43 and autophagy, followed by apoptosis ENSG00000102189 PMC9272004__F2 Heme Synthesis by Mitochondrial Homeostasis Proteins ENSG00000144659 ENSG00000166855 ENSG00000135776 ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000256269 ENSG00000188690 ENSG00000115657 ENSG00000284936 PMC7364656__F7 Sal and Das together synergistically inhibited the BRCA1 pathway in the MDA-MB-468 cell line ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000115415 ENSG00000166851 ENSG00000123268 ENSG00000156273 PMC5938062__F6 TAK-733 under an Ang II-induced signaling pathway in vascular remodeling ENSG00000162692 PMC9456253__F4 Downstream Effects of Mutations in SOD1 and TARDBP Converge on Gene Expression Impairment in Patient-Derived Motor Neurons ENSG00000087510 ENSG00000028277 ENSG00000001167 ENSG00000198755 ENSG00000163064 ENSG00000147133 ENSG00000089157 ENSG00000138326 ENSG00000129514 ENSG00000166337 ENSG00000116017 ENSG00000137203 ENSG00000130699 ENSG00000130332 ENSG00000168310 ENSG00000179348 ENSG00000177932 ENSG00000109705 ENSG00000178913 ENSG00000100811 ENSG00000120656 ENSG00000137273 ENSG00000109320 ENSG00000173039 ENSG00000105698 ENSG00000168610 ENSG00000064995 ENSG00000132170 ENSG00000106459 ENSG00000115415 ENSG00000175745 ENSG00000177606 ENSG00000075891 ENSG00000107485 ENSG00000148835 ENSG00000198911 PMC6664006__F8 Proposed model to explain how COX-2 might be essential in the stimulatory pathway for ROS production and increased expression of profibrotic genes mediated by PRR activation ENSG00000086991 PMC529535__F1 Two models relating Akt and Tsc2 in cell growth control in Drosophila PMC4333106__F2 Canonical and alternative androgen biosynthesis pathways PMC5753567__F1 Relation between activated WNT/Beta-catenin pathway and Warburg effect in ASD ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC8377336__F3 On the nutritional and therapeutic effects of ketone body d-Beta-hydroxybutyrate ENSG00000162711 PMC4429755__F1 Regulation of miRNA biogenesis as an integrated component of growth factor signaling ENSG00000291507 ENSG00000128191 ENSG00000113360 PMC4429755__F3 Regulation of miRNA biogenesis as an integrated component of growth factor signaling ENSG00000128191 ENSG00000113360 PMC8552790__F9 Schematic diagram of GTF2F2 related functions ENSG00000136807 ENSG00000136997 ENSG00000171791 PMC8585009__F5 Diagram depicting the 2 branches of the fat remodeling program controlled by neuronal activation of Hsf-1 PMC8170687__F1 Integrin function is regulated by conformational activation and vesicular traffic and is crucially involved in mechanosensing and TKR signaling ENSG00000103365 ENSG00000026508 PMC9505042__F7 TGFB/SMAD Signaling Pathway Prevents Follicular Atresia by Upregulating MORC2 ENSG00000171791 ENSG00000133422 PMC7893589__F3 Effects of miR-320 on glucose and lipid metabolism in cardiomyocytes ENSG00000135218 ENSG00000123908 PMC9348444__F4 Comprehensive role of SARS‐CoV‐2 spike glycoprotein in regulating host signaling pathway ENSG00000174125 ENSG00000130234 ENSG00000184012 PMC7571393__F2 Summary of the regulatory network and mechanisms of circ_ASPH in CCA cells.Abbreviations: ASPH: aspartate B‐hydroxylase; CCA: cholangiocarcinoma ENSG00000160179 ENSG00000198363 PMC3045450__F4 NAViGaTing the Micronome – Using Multiple MicroRNA Prediction Databases to Identify Signalling Pathway-Associated MicroRNAs ENSG00000150907 ENSG00000108443 ENSG00000105647 ENSG00000121879 ENSG00000187840 PMC5242433__F6 Cell-Based Systems Biology Analysis of Human AS03-Adjuvanted H5N1 Avian Influenza Vaccine Responses: A Phase I Randomized Controlled Trial ENSG00000145604 ENSG00000132646 ENSG00000123374 ENSG00000091651 ENSG00000277273 ENSG00000276876 ENSG00000093009 PMC10886007__F3 TGFB/SMAD signaling pathway ENSG00000170365 ENSG00000137834 ENSG00000135414 PMC10886007__F2 Mitochondria-dependent apoptosis pathway ENSG00000171791 ENSG00000115317 PMC9604720__F1 Brain-Derived Neurotrophic Factor in Immune-Related Diseases: A Narrative Review ENSG00000087245 ENSG00000140564 ENSG00000100985 ENSG00000122194 PMC3552884__F8 Integrated regulation of autophagy and apoptosis by EEF2K controls cellular fate and modulates the efficacy of curcumin and velcade against tumor cells ENSG00000168209 ENSG00000128272 ENSG00000198793 ENSG00000284161 PMC10886007__F5 PI3K/Akt/mTOR signaling pathway ENSG00000150907 PMC5661609__F1 Dysregulation of KRAS signaling pathway in PDAC tumors compared with that in the paired adjacent non-malignant tissues ENSG00000157764 ENSG00000291971 ENSG00000198793 ENSG00000115904 ENSG00000127955 ENSG00000155903 ENSG00000169032 ENSG00000121879 ENSG00000160691 ENSG00000065135 ENSG00000017797 ENSG00000149269 ENSG00000006451 PMC10886007__F4 AMPK/SIRT1/PGC-1A signaling pathway ENSG00000096717 ENSG00000106459 ENSG00000079999 PMC4895609__F1 Simplified schematic illustration of PI3K/Akt and mitogen‐activated protein kinase (MAPK) signaling pathways in thyroid cancer ENSG00000157764 ENSG00000198793 PMC9418004__F8 Mechanistic illustration showed PLAA-METTL3-TRPC3 axis in ovarian cancer ENSG00000138741 ENSG00000137055 ENSG00000165819 PMC6855007__F10 Illustration representing the mechanisms of compound 1-induced human breast cancer cell apoptosis ENSG00000149311 ENSG00000175054 ENSG00000002330 ENSG00000146648 PMC9163393__F3 Metabolic and Non-Metabolic Roles of UCK2 in Tumor Progression ENSG00000087245 ENSG00000138798 ENSG00000143179 ENSG00000168610 ENSG00000146648 PMC5973841__F2 Filoviruses inhibit the type I IFN response at multiple steps ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000142166 PMC7854502__F5 Developmental pathways in liver cancer ENSG00000125398 ENSG00000168214 ENSG00000118785 ENSG00000168036 ENSG00000163501 PMC7826004__F3 Pernio (Chilblains), SARS-CoV-2, and COVID Toes Unified Through Cutaneous and Systemic Mechanisms ENSG00000090402 ENSG00000130234 ENSG00000184012 PMC9657162__F8 Z. morio Hemolymph Relieves E. coli-Induced Mastitis by Inhibiting Inflammatory Response and Repairing the Blood–Milk Barrier ENSG00000162711 ENSG00000145782 ENSG00000057663 PMC5655367__F4 Modulations of adaptable responsive genes in acclimation ENSG00000002330 ENSG00000288269 ENSG00000291971 ENSG00000138798 ENSG00000169047 ENSG00000198793 ENSG00000182759 ENSG00000169291 ENSG00000136997 ENSG00000158825 ENSG00000198670 ENSG00000121853 ENSG00000171105 ENSG00000112964 ENSG00000174417 ENSG00000113070 ENSG00000158458 ENSG00000102539 ENSG00000075073 ENSG00000285456 ENSG00000110395 ENSG00000177606 ENSG00000185231 ENSG00000196689 ENSG00000113494 PMC2939362__F1 Domain organization of proteins in the Hh signaling pathway ENSG00000180447 ENSG00000164161 ENSG00000144857 ENSG00000138798 ENSG00000128602 PMC7793976__F1 Action of emapalumab ENSG00000115415 PMC7852140__F3 Metabolic pathway of norvancomycin biosynthesis up-regulated in high-yield strain ENSG00000122966 ENSG00000172005 PMC6059757__F15 PPI networks for key KEGG pathways ENSG00000107562 ENSG00000166086 ENSG00000169031 ENSG00000135111 ENSG00000182985 ENSG00000066405 ENSG00000134245 ENSG00000283060 ENSG00000120903 ENSG00000078549 ENSG00000154342 ENSG00000112964 ENSG00000088827 ENSG00000119535 ENSG00000197471 ENSG00000120693 ENSG00000099957 ENSG00000171596 ENSG00000066468 ENSG00000171777 ENSG00000127533 ENSG00000160867 ENSG00000126895 ENSG00000174059 ENSG00000162104 ENSG00000204217 PMC5074086__F1 Pheochromocytoma: The First Metabolic Endocrine Cancer ENSG00000131473 ENSG00000146701 ENSG00000062485 PMC11627363__F7 Golgi apparatus stress response pathway activated by AIV infection ENSG00000064225 ENSG00000168282 ENSG00000114573 PMC3289121__F5 IPA illustrating the predicted effect of milk removal on PI3K signaling in T lymphocytes ENSG00000112977 PMC6021929__F5 Pharmacoepigenomics informatics pipeline defines a pathway of novel and known warfarin pharmacogenomics variants ENSG00000281879 ENSG00000198734 ENSG00000171560 ENSG00000151006 PMC7870789__F1 Tumorigenic mechanisms in somatotroph cells ENSG00000110711 ENSG00000165370 ENSG00000010310 PMC5370075__F4A Biomechanical relationships between the corneal endothelium and Descemet’s membrane ENSG00000163914 ENSG00000198670 ENSG00000150457 ENSG00000131023 PMC9951170__F2 When AHR signaling pathways meet viral infections ENSG00000291971 ENSG00000106546 PMC8899182__F2 Regulation of PBXs and their emerging role in cancer ENSG00000074181 ENSG00000168610 PMC3192251__F2 NPC and CF converge on multiple intracellular trafficking pathways ENSG00000119655 ENSG00000141458 ENSG00000001626 PMC9576519__F9 Neurotrophin3 promotes hepatocellular carcinoma apoptosis through the JNK and P38 MAPK pathways ENSG00000185652 ENSG00000171720 PMC6274888__F1 Response to immunotherapy in pancreatic ductal adenocarcinoma (PDAC) relies on destroying cancer cells as well as on breaking the stromal barrier and flaring up immune function ENSG00000118520 ENSG00000164690 ENSG00000121966 PMC9598694__F9 Thiamine Supplementation Alleviates Lipopolysaccharide-Triggered Adaptive Inflammatory Response and Modulates Energy State via Suppression of NFKB/p38 MAPK/AMPK Signaling in Rumen Epithelial Cells of Goats ENSG00000136869 ENSG00000096717 PMC5838032__F5 Overview of the metabolism of sugars, amino acids, and related compounds ENSG00000069482 ENSG00000145020 PMC6157734__F2 Human CARD9 signaling pathway ENSG00000081041 ENSG00000187796 ENSG00000163739 ENSG00000125538 ENSG00000164400 PMC7648118__F2 Therapeutic strategies targeting the NMJ in dystrophic muscle ENSG00000134569 ENSG00000030304 ENSG00000165917 PMC3634610__F2 Signaling network of Dectin-1 ENSG00000104856 ENSG00000162711 ENSG00000187796 ENSG00000197943 PMC6711424__F1 CNVs, SNVs/indels on histamine‐related metabolism and signalling pathways ENSG00000100290 ENSG00000185386 ENSG00000112499 ENSG00000140287 ENSG00000188130 ENSG00000118640 PMC6021929__F2 Pharmacoepigenomics informatics pipeline defines a pathway of novel and known warfarin pharmacogenomics variants ENSG00000038427 ENSG00000167720 ENSG00000172572 ENSG00000116741 ENSG00000154310 ENSG00000132535 ENSG00000189001 PMC3634610__F3 ITAM-like-bearing CTLRs within the Dectin-1 cluster ENSG00000197992 ENSG00000197943 PMC5943343__F7 Proposed Model: The figure shows that mutation in GNE inhibits sialic acid synthesis that may cause hyposialylation of IGF-1R ENSG00000159921 ENSG00000002330 ENSG00000171791 PMC8071448__F2 Examples of functions of human disease-related retrocopies ENSG00000171105 PMC9226217__F2 Therapeutic cell engineering: designing programmable synthetic genetic circuits in mammalian cells ENSG00000174125 ENSG00000170458 ENSG00000172005 ENSG00000172936 PMC8351721__F7 Prognoses and genomic analyses of proteasome 26S subunit, ATPase (PSMC) family genes in clinical breast cancer ENSG00000106683 ENSG00000070831 ENSG00000134982 ENSG00000163914 PMC9603894__F1 Oncolyic Virotherapy for Prostate Cancer: Lighting a Fire in Winter ENSG00000131323 ENSG00000276561 PMC8790913__F8 SPI1-TYROBP-FCER1G network in oncogenesis and prognosis of osteosarcoma, and its association with immune infiltration ENSG00000182578 ENSG00000135077 ENSG00000011600 ENSG00000277263 ENSG00000158869 ENSG00000277943 PMC8750882__F12 Extracellular Vesicles Derived from Bone Marrow in an Early Stage of Ionizing Radiation Damage Are Able to Induce Bystander Responses in the Bone Marrow ENSG00000087095 ENSG00000163251 ENSG00000162337 ENSG00000095739 ENSG00000169884 ENSG00000168036 ENSG00000175029 PMC11266911__F2 Molecular mechanism of antitumoral properties of 6‐shogaol ENSG00000112576 ENSG00000148400 ENSG00000134057 ENSG00000170558 ENSG00000132646 ENSG00000198793 ENSG00000114315 ENSG00000168610 PMC6510997__F1 Immune signaling network in MS ENSG00000171105 ENSG00000111537 ENSG00000291971 ENSG00000177606 ENSG00000173039 ENSG00000150455 PMC6414715__F10 Activation of antiviral pathways in Atlantic cod ENSG00000159128 ENSG00000239732 ENSG00000111537 ENSG00000100906 ENSG00000109320 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000168040 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC5010470__F1 NF-kB signaling pathways ENSG00000104856 ENSG00000118503 ENSG00000173039 ENSG00000127311 PMC9014844__F3 Using Intermittent Fasting as a Non-pharmacological Strategy to Alleviate Obesity-Induced Hypothalamic Molecular Pathway Disruption ENSG00000111537 PMC9306208__F4 Senescence in osteoarthritis: from mechanism to potential treatment ENSG00000149311 ENSG00000175054 ENSG00000197635 ENSG00000204520 PMC8780935__F3 Research progress on the hedgehog signalling pathway in regulating bone formation and homeostasis ENSG00000128272 ENSG00000164161 ENSG00000168036 ENSG00000164690 ENSG00000128602 ENSG00000163501 ENSG00000125084 PMC6092675__F8 Inhibition of mTOR activity with rapamycin ENSG00000198793 PMC3365794__F2 Model showing arterial, venous, and lymphatic cell fate specification in the developing embryos ENSG00000196411 ENSG00000117707 ENSG00000118257 ENSG00000203883 PMC7333391__F5 Postulated mechanism by which CagA promotes the expression of IL-6 in gastric cancer ENSG00000145623 ENSG00000099985 ENSG00000168610 PMC4827621__F9 Deletion of KvB1.1 subunit leads to electrical and haemodynamic changes causing cardiac hypertrophy in female murine hearts ENSG00000285109 ENSG00000125538 ENSG00000197616 PMC3311240__F11 Muscle cell signaling in response to 1E3 ENSG00000070831 ENSG00000167941 ENSG00000149269 PMC3978640__F6 Blocking the transforming growth factor B (TGFB) signalling pathway PMC3324906__F1 Pivotal role of E-cadherin, Beta-catenin, and transforming growth factor B (TGFB) and Wnt signaling pathways in an epithelial-mesenchymal transition (EMT) program ENSG00000134982 PMC8693183__F5 Gill Transcriptomic Responses to Toxin-producing Alga Prymnesium parvum in Rainbow Trout ENSG00000162889 ENSG00000175899 ENSG00000127191 ENSG00000168610 ENSG00000132693 PMC9013079__F8 L-theanine prevents progression of nonalcoholic hepatic steatosis by regulating hepatocyte lipid metabolic pathways via the CaMKKBeta-AMPK signaling pathway ENSG00000042832 ENSG00000198793 ENSG00000169710 PMC8267469__F7 Systems Pharmacology–Based Dissection of Anti-Cancer Mechanism of Traditional Chinese Herb Saussurea involucrata ENSG00000132906 ENSG00000226275 ENSG00000002330 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000131323 ENSG00000127191 ENSG00000168610 PMC5075921__F4 Knowledge-guided fuzzy logic modeling to infer cellular signaling networks from proteomic data ENSG00000115008 ENSG00000163235 ENSG00000095015 ENSG00000135341 PMC6882011__F4 Pathway display visualisation of significant changes in primary/intermediary metabolite abundances observed between COL2246 and ECU72 during the infestation cycle ENSG00000197429 ENSG00000132478 ENSG00000119912 PMC8317513__F5 FHL1 Inhibits the Progression of Colorectal Cancer by Regulating the Wnt/Beta-Catenin Signaling Pathway ENSG00000138795 ENSG00000281324 ENSG00000137673 ENSG00000162337 ENSG00000134982 ENSG00000135446 ENSG00000168036 ENSG00000022267 ENSG00000196628 PMC5260790__F3 Differential methylation network of schizophrenia ENSG00000131469 ENSG00000173821 ENSG00000109452 ENSG00000005073 ENSG00000147596 ENSG00000275700 ENSG00000130414 ENSG00000169710 ENSG00000125871 ENSG00000163541 ENSG00000137845 ENSG00000070669 ENSG00000163882 ENSG00000170775 ENSG00000122741 ENSG00000134371 ENSG00000126247 ENSG00000105991 ENSG00000164068 ENSG00000198010 ENSG00000136146 ENSG00000085719 ENSG00000144535 ENSG00000132329 ENSG00000135482 ENSG00000119669 ENSG00000284869 ENSG00000136877 ENSG00000213782 ENSG00000143458 ENSG00000164654 ENSG00000187840 ENSG00000106829 ENSG00000120063 ENSG00000111145 ENSG00000182240 ENSG00000167775 ENSG00000076321 ENSG00000198783 ENSG00000107938 ENSG00000248643 ENSG00000105705 ENSG00000122034 ENSG00000181315 ENSG00000132128 ENSG00000148832 ENSG00000117625 ENSG00000135341 ENSG00000114859 ENSG00000070444 ENSG00000119608 ENSG00000166501 ENSG00000108599 ENSG00000168310 ENSG00000104081 ENSG00000184983 ENSG00000138594 ENSG00000099957 ENSG00000135698 ENSG00000167522 ENSG00000143512 ENSG00000123685 ENSG00000123364 ENSG00000148660 ENSG00000197299 ENSG00000112697 ENSG00000164690 ENSG00000128602 PMC9409657__F6 Angiotensin II Receptor Blocker Irbesartan Enhanced SIRT1 longevity Signaling Replaces the Mitochondrial Biogenetic Survival Pathway to Attenuate Hypertension-Induced Heart Apoptosis ENSG00000168040 ENSG00000096717 ENSG00000026103 PMC2757955__F10 Proposed model of IGFBP-3 modulation of growth factor receptor activation mediated by S1P ENSG00000157933 ENSG00000138798 ENSG00000146648 PMC2100073__F6 Filamentation signaling pathway recovered completely ENSG00000070831 ENSG00000197601 PMC86880__F1 Receptor proximal signaling pathway for IL-1 ENSG00000172936 ENSG00000175104 PMC6585752__F2 Characterization of network connectivity between highly expressed interferon (IFN) response genes ENSG00000088827 ENSG00000089127 ENSG00000157601 ENSG00000115267 ENSG00000185745 ENSG00000184979 ENSG00000132530 ENSG00000152778 ENSG00000134321 ENSG00000133106 ENSG00000134326 ENSG00000138642 ENSG00000135114 ENSG00000059378 ENSG00000111331 PMC8047301__F3 Leucine sensing signaling pathway upstream of mTORC1 and the potential role of exercise PMC2949481__F2 Insulin, IGF-I and IGF-II signaling through the IGF-IR ENSG00000002330 ENSG00000169047 ENSG00000198793 PMC7035994__F2 Polarity proteins in oncogenesis ENSG00000274429 ENSG00000073350 PMC3073074__F1 The pathway of propionyl-CoA to succinyl-CoA metabolism is displayed ENSG00000175198 ENSG00000114054 ENSG00000124370 ENSG00000151611 PMC4163915__F11 Model is presented whereby serine phosphorylation of IRS-1 serves as a mediator of Ang II to inhibit insulin-induced Akt Thr308 phosphorylation ENSG00000113070 ENSG00000198793 ENSG00000146648 PMC7035994__F1 Apico-basal polarity proteins play a critical role in homeostatic control of cell density ENSG00000274429 ENSG00000073350 ENSG00000131899 ENSG00000007047 ENSG00000132849 ENSG00000072415 PMC4564397__F1 HOCl signaling pathway A ENSG00000167419 PMC1526464__F8 Bile acid and cytokine inhibition of CYP7A1 gene transcription ENSG00000167910 ENSG00000125538 PMC6230871__F7 Differentially expressed miRNA-mRNA pairs in nuclear factor of activated T cells (NFAT) cardiac hypertrophy pathway from NHE1 transgenic mouse hearts ENSG00000150281 ENSG00000069482 ENSG00000253506 ENSG00000095321 ENSG00000128342 ENSG00000140443 PMC4564397__F2 The NO/peroxynitrite signaling pathway A ENSG00000127948 ENSG00000167419 PMC4564397__F4 Salicylic acid and anthocyanidins use different strategies to inhibit tumor cell protective catalase ENSG00000108582 ENSG00000184357 PMC6230871__F3 Genes altered in NHE1 transgenic hearts were enriched in KEGG hypertrophic cardiomyopathy (HCM) pathway ENSG00000102683 ENSG00000160808 ENSG00000197616 ENSG00000170624 ENSG00000198947 PMC6360084__F8 Identification, expression, and phylogenetic analyses of terpenoid biosynthesis-related genes in secondary xylem of loblolly pine (Pinus taeda L.) based on transcriptome analyses ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC3793031__F2 Symbiotic signaling downstream of oscillations ENSG00000178607 ENSG00000136997 PMC8847772__F1 Search for Biomarkers and Treatments in Chagas Disease: Insights From TGF-Beta Studies and Immunogenetics PMC6340093__F1 Interacting enzyme in the monolignol biosynthetic pathway ENSG00000104237 ENSG00000102977 ENSG00000084774 PMC7022462__F2 Phytochemicals and Gastrointestinal Cancer: Cellular Mechanisms and Effects to Change Cancer Progression ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC10532123__F6 Myogenetic Oligodeoxynucleotide Induces Myocardial Differentiation of Murine Pluripotent Stem Cells ENSG00000166823 ENSG00000285109 ENSG00000147869 ENSG00000183072 ENSG00000128052 ENSG00000174804 ENSG00000134853 ENSG00000204531 ENSG00000188095 ENSG00000197616 ENSG00000089225 ENSG00000016082 PMC3809361__F1 Metabolism of cancer cells is regulated by signaling pathways related to oncogenes and tumor-suppressor genes ENSG00000198793 ENSG00000136997 ENSG00000078237 ENSG00000284194 PMC3979678__F3 Global Changes in Gene Expression of Barrett's Esophagus Compared to Normal Squamous Esophagus and Gastric Cardia Tissues ENSG00000128016 ENSG00000135218 ENSG00000105329 ENSG00000197632 ENSG00000138594 ENSG00000010278 ENSG00000157005 ENSG00000145113 ENSG00000150782 ENSG00000138764 ENSG00000163235 ENSG00000169474 ENSG00000131724 ENSG00000151914 ENSG00000277401 ENSG00000136689 PMC7693871__F7 The pathway of Ac2-26 effect: (A) the mechanism of the anti-inflammatory responses of Ac2-26 in HaCaT cells ENSG00000168610 PMC6978911__F8 Schematic comparison between CiTLR22a- and CiTLR22b-mediated signaling pathways ENSG00000172936 ENSG00000090376 ENSG00000276561 PMC11534861__F2 Histone lactylation in cancer ENSG00000170775 ENSG00000136261 ENSG00000179094 PMC8431490__F3 The BH4 Cofactor in Nitric Oxide Synthase Activity and Cancer Progression: Two Sides of the Same Coin ENSG00000049323 ENSG00000168036 ENSG00000112715 ENSG00000162692 ENSG00000168610 PMC6249275__F3 Keap1-dependent and Keap1-independent mediated Nrf2 signaling ENSG00000178573 ENSG00000100387 ENSG00000106546 ENSG00000079999 PMC6249275__F1 Natural products activating Nrf2 signaling pathway ENSG00000135218 ENSG00000100387 ENSG00000160179 ENSG00000079999 PMC8087812__F2 Response of green leaf volatile (GLV) biosynthesis in MeJA-primed fresh tea leaves PMC4592906__F2 TNF-induced programmed cell death pathways ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 PMC8247436__F4 Diverse Roles of TgMIC1/4/6 in the Toxoplasma Infection ENSG00000172936 ENSG00000204520 PMC8056770__F1 Pleiotropic roles of leptin in metabolism, immunity, and cancer ENSG00000198793 ENSG00000049768 ENSG00000168610 PMC8841363__F2 Network based systems biology approach to identify diseasome and comorbidity associations of Systemic Sclerosis with cancers ENSG00000135549 ENSG00000088826 ENSG00000148832 ENSG00000163739 ENSG00000067798 ENSG00000140044 ENSG00000178726 ENSG00000038382 ENSG00000204262 ENSG00000173369 ENSG00000149089 ENSG00000163734 ENSG00000155659 ENSG00000125810 ENSG00000285049 ENSG00000116771 ENSG00000177575 ENSG00000112280 ENSG00000081041 ENSG00000119943 ENSG00000142920 ENSG00000171033 ENSG00000159189 ENSG00000102172 ENSG00000260314 ENSG00000185946 ENSG00000173372 ENSG00000170458 ENSG00000111799 ENSG00000084636 ENSG00000099810 ENSG00000136160 ENSG00000123505 ENSG00000182551 ENSG00000038945 ENSG00000116649 ENSG00000123689 PMC4329480__F1 Molecular mechanisms regulating mitophagy ENSG00000038532 ENSG00000158828 ENSG00000135093 PMC11534861__F4 Relevant mechanisms of lactylation in the development of cancer by modulating TME ENSG00000112715 ENSG00000049768 ENSG00000165819 PMC2981143__F1 Folate metabolism and its contributions to physiological processes ENSG00000228716 ENSG00000133027 PMC4423527__F1 Neddylation pathways influencing NFKB and HIF-1A ENSG00000111537 PMC5319840__F3 Tgfbr2 cKO CD34+ SCC cells upregulate genes implicated in invasive human cancers ENSG00000047410 ENSG00000039537 ENSG00000101265 ENSG00000155926 ENSG00000033122 ENSG00000126860 ENSG00000043462 ENSG00000087303 ENSG00000236625 ENSG00000274619 ENSG00000108691 ENSG00000069482 ENSG00000118785 ENSG00000060491 ENSG00000015285 ENSG00000167996 ENSG00000277263 ENSG00000136160 ENSG00000100985 ENSG00000122862 ENSG00000187955 PMC2640984__F3 Distribution between short and long flap removal pathways ENSG00000138346 ENSG00000140451 PMC3181439__F1 Jun N-terminal kinase signaling pathway ENSG00000142192 ENSG00000284774 ENSG00000127191 ENSG00000168610 ENSG00000162999 PMC6831194__F5 Discovery of metabolic pathway identified in both optimal cutting temperature-embedded and formalin-fixed paraffin-embedded samples ENSG00000151376 ENSG00000081181 ENSG00000262785 ENSG00000135423 ENSG00000162396 ENSG00000196839 ENSG00000173627 ENSG00000198931 ENSG00000205309 ENSG00000102967 ENSG00000070669 ENSG00000158125 ENSG00000156110 ENSG00000173599 ENSG00000158825 ENSG00000143179 ENSG00000166123 ENSG00000091140 ENSG00000115419 ENSG00000119125 ENSG00000084774 PMC4834538__F7 Knee loading inhibits osteoclast lineage in a mouse model of osteoarthritis ENSG00000154342 ENSG00000131196 PMC10758155__F6 Huaier suppresses cell viability, migration and invasion in human non-small cell lung cancer via lncRNA DLEU2/miR-212-5p/ELF3 axis ENSG00000163435 ENSG00000074181 PMC11988921__F1 Unfolded protein response (UPR) signaling pathway consists of three major branches: activating transcription factor 6 (ATF6), inositol-requiring enzyme-1A (IRE1A), and PKR-like ER kinase (PERK) ENSG00000128272 ENSG00000100219 ENSG00000127191 PMC9199543__F3 Understanding the Role of Histone Deacetylase and their Inhibitors in Neurodegenerative Disorders: Current Targets and Future Perspective ENSG00000198793 ENSG00000196591 ENSG00000095303 ENSG00000283100 PMC5905465__F1 Structure of NFKB members.Notes: The NFKB family consists of three proteins with a transactivation domain (RelA [p65], cRel, and RelB) and two proteins lacking a transactivation domain (p105/p50 and p100/p52) ENSG00000104856 ENSG00000111321 PMC4084552__F1 IL-33/ST2 signaling pathway ENSG00000137033 ENSG00000172936 ENSG00000185187 ENSG00000175104 PMC2932466__F3 Signal transduction mechanisms involved in the mediation of cellular responses induced by secreted MIC-1 cytokine in certain cancer cells ENSG00000146648 PMC7066027__F5 Roles of miR-30c family members in drug resistance ENSG00000151239 ENSG00000146648 PMC7066027__F4 Roles of miR-30c family members in carcinogenesis, metastasis and invasion ENSG00000151239 PMC1380241__F1 CoQ10biosynthetic pathway with eight known biosynthetic enzymes denoted as COQ1–COQ8 ENSG00000132423 ENSG00000119723 ENSG00000110871 ENSG00000173085 ENSG00000167186 PMC4928589__F2 Autophagy–Lysosomal Pathway in Neurodegeneration: A TFEB Perspective ENSG00000177169 ENSG00000198793 ENSG00000155792 ENSG00000164327 PMC11049089__F1 Signaling cascades of TLR4 and TLR2 receptors ENSG00000226275 ENSG00000167207 ENSG00000154589 ENSG00000177606 ENSG00000172936 ENSG00000175104 ENSG00000106100 ENSG00000184216 PMC5520418__F2 PTEN functions in T-cell development, activation and differentiation ENSG00000134982 PMC8999457__F2 Neurotropic RNA Virus Modulation of Immune Responses within the Central Nervous System ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000125347 ENSG00000276561 ENSG00000101695 ENSG00000164342 PMC1383660__F6 Intracellular signalling pathways activated by leptin ENSG00000245848 ENSG00000168610 PMC8290198__F1 Multiple Roles of the Cytosolic Adapter Proteins ADAP, SKAP1 and SKAP2 for TCR/CD3 -Mediated Signaling Events ENSG00000113263 ENSG00000124181 PMC1383660__F5 Intracellular signalling pathways activated by leptin ENSG00000124102 PMC2494808__F3 Graphical representation of connections between receptors and pathways implicated in NTS baroreflex modulation by pharmacological studies ENSG00000002330 ENSG00000070831 ENSG00000148926 ENSG00000111816 PMC1829419__F4 Hypothetical regulatory network influencing honeybee pollen foraging behavior modulated by insulin-like signaling and its effects on ovarian development ENSG00000127445 ENSG00000102309 PMC4682888__F2 Integration of Akt and mTORC1 signaling into the IL-4R and TLR4 pathways ENSG00000136869 ENSG00000105639 PMC4518158__F1 Unfolded protein response ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC7277983__F2 TNF-TNFR2 signalling pathway in the immunosuppressive cells ENSG00000137275 ENSG00000127191 PMC7400846__F2 Cholesterol and bile acid biosynthesis ENSG00000138075 ENSG00000169291 ENSG00000130164 ENSG00000186480 ENSG00000073734 ENSG00000185591 ENSG00000120437 ENSG00000167182 ENSG00000143921 PMC7564116__F3 Functions of circRNAs in colorectal cancer (CRC) ENSG00000105810 PMC7007672__F3 Molecular pathways in embryogenesis of the liver ENSG00000119547 ENSG00000245848 ENSG00000285109 ENSG00000135111 ENSG00000117707 ENSG00000152804 PMC8859251__F9 Biomarker Value of miR-221 and miR-222 as Potential Substrates in the Differential Diagnosis of Papillary Thyroid Cancer Based on Data Synthesis and Bioinformatics Approach ENSG00000090402 ENSG00000002330 ENSG00000067057 ENSG00000285109 ENSG00000291971 ENSG00000166278 PMC9686346__F3 Health benefits of Nigella sativa on diabetes mellitus and its complications: A review from laboratory studies to clinical trials ENSG00000042832 ENSG00000167419 PMC2885511__F2 Diagram of PDGF-D cross-talks with other pathways ENSG00000170962 ENSG00000198793 ENSG00000122194 PMC8068079__F2 Base excision repair, nucleotide excision repair and mismatch repair pathway ENSG00000143799 ENSG00000132646 ENSG00000177084 PMC8615493__F6A Mechanical Stretching-Induced Traumatic Brain Injury Is Mediated by the Formation of GSK-3Beta-Tau Complex to Impair Insulin Signaling Transduction ENSG00000169047 PMC2782433__F1 COPPER ACTIVATION OF NFKB SIGNALING IN HEPG2 CELLS ENSG00000104856 ENSG00000109320 ENSG00000010818 ENSG00000172336 ENSG00000091879 ENSG00000120937 ENSG00000137801 ENSG00000171631 ENSG00000138166 ENSG00000106070 ENSG00000284099 ENSG00000173846 ENSG00000115009 ENSG00000155657 PMC8502815__F7 Beta-Carotene in Colonic Inflammation and Intestinal Barrier Integrity ENSG00000170458 ENSG00000125538 ENSG00000136869 ENSG00000132693 PMC8636732__F2 Understanding the Complex Milieu of Epithelial-Mesenchymal Transition in Cancer Metastasis: New Insight Into the Roles of Transcription Factors ENSG00000019991 ENSG00000169554 ENSG00000134982 ENSG00000149269 ENSG00000170558 ENSG00000168036 ENSG00000146648 ENSG00000133027 PMC4509066__F2 Signaling pathway of cell apoptosis under cordycepin stress ENSG00000102871 ENSG00000120868 ENSG00000168040 PMC6874977__F3 PPI network analysis ENSG00000163464 ENSG00000172410 ENSG00000179934 ENSG00000107562 ENSG00000163739 ENSG00000171049 ENSG00000124875 ENSG00000188958 ENSG00000171388 ENSG00000171051 ENSG00000108849 ENSG00000288411 ENSG00000163421 ENSG00000163734 ENSG00000169429 ENSG00000164220 ENSG00000127928 ENSG00000151882 ENSG00000081041 ENSG00000164128 ENSG00000166573 ENSG00000163736 ENSG00000157005 ENSG00000124205 ENSG00000183395 ENSG00000069482 ENSG00000115263 ENSG00000255398 ENSG00000180616 ENSG00000177464 PMC9408960__F1 Ectodysplasin A (EDA) Signaling: From Skin Appendage to Multiple Diseases ENSG00000104856 ENSG00000186197 ENSG00000135960 ENSG00000049249 ENSG00000175104 PMC10179184__F2 Mechanism of CYLD function in oxidative stress-induced DNA damage ENSG00000083799 ENSG00000154124 PMC11332896__F2 Signaling pathways involved in muscle atrophy during cachexia ENSG00000198793 ENSG00000140443 PMC10236263__F6 Models of the positive regulatory feedback loop of p65/miR-27a-3p/TAB3/NFKB axis ENSG00000157625 ENSG00000131323 ENSG00000006062 PMC4357015__F1 Structure, Function and Inhibition of the Phosphoethanolamine Methyltransferases of the Human Malaria Parasites Plasmodium vivax and Plasmodium knowlesi ENSG00000173599 PMC8394995__F2 BRCAness as a Biomarker of Susceptibility to PARP Inhibitors in Glioblastoma Multiforme ENSG00000149311 ENSG00000175054 ENSG00000127663 ENSG00000198793 ENSG00000136997 ENSG00000066135 ENSG00000051180 ENSG00000146648 PMC7857921__F4 Selected pathways up- and downregulated by the additional hemorrhagic shock ENSG00000143546 ENSG00000170458 ENSG00000163220 ENSG00000197405 ENSG00000136869 ENSG00000168615 ENSG00000150455 PMC9537693__F8 4-(2-Butyl-6,7-dichloro-2-cyclopentyl-indan-1-on-5-yl) oxobutyric acid inhibits angiogenesis via modulation of vascular endothelial growth factor receptor 2 signaling pathway ENSG00000112715 ENSG00000168610 PMC11909752__F8 The proposed mechanism for chronic adrenergic stimulation induced heart failure via cAMP-PKA-PDE4D signaling pathway and protective mechanism of PDE4D inhibition ENSG00000158828 ENSG00000096717 ENSG00000113448 PMC4876997__F6 Establishment of a Conditionally Immortalized Wilms Tumor Cell Line with a Homozygous WT1 Deletion within a Heterozygous 11p13 Deletion and UPD Limited to 11p15 ENSG00000164690 ENSG00000163501 PMC524028__F2 Regulation of the mTOR signaling pathway PMC12055817__F2 Possible mechanisms underlying crosstalk between microglia and astroglia ENSG00000169245 ENSG00000162711 ENSG00000108691 ENSG00000163235 ENSG00000007171 ENSG00000106546 PMC11772370__F3 Protein lactonylation modification is an important influence in the process that is HIF-1-mediated HMGB1 activity ENSG00000198793 ENSG00000189403 ENSG00000172936 ENSG00000136869 PMC12055817__F3 Antidepressant mechanism of natural anti-inflammatory products ENSG00000162711 ENSG00000136869 PMC3755464__F3 Recombination-independent interstrand crosslink repair pathway in vertebrates PMC5354803__F3 Oxidative stress, a trigger of hepatitis C and B virus-induced liver carcinogenesis ENSG00000116133 ENSG00000168036 PMC11772370__F1 Metabolic crosstalk between neurons and glia involving lactate is implicated in epilepsy ENSG00000162711 ENSG00000189403 PMC5354803__F5 Oxidative stress, a trigger of hepatitis C and B virus-induced liver carcinogenesis ENSG00000124216 ENSG00000125538 ENSG00000020633 ENSG00000168610 PMC6753173__F5 Schematic diagram of the pathogen-derived molecules used to escape cytokine-sensing pathways in cells ENSG00000213928 ENSG00000105397 ENSG00000144895 ENSG00000115415 ENSG00000142166 PMC6753173__F4 A schematic diagram of pathogen-derived molecules used to escape intracellular DNA sensing pathways ENSG00000183735 ENSG00000164430 ENSG00000163568 ENSG00000163565 PMC2777122__F2 Step 2: T-cell activation and costimulation ENSG00000134982 PMC6397695__F2 IDO1-Kynurenine-AhR signaling in TME immunosuppression ENSG00000111537 ENSG00000106546 PMC4215179__F1 Protein trafficking of pericellular proteases ENSG00000087245 ENSG00000100985 PMC6514093__F3 Predicted arsenic resistance pathway in R ENSG00000116984 PMC7956936__F8 Mechanistic view of anthracycline-induced cardiotoxicity ENSG00000120868 ENSG00000168040 PMC9242064__F2 Inflammatory bowel disease and cardiovascular diseases: a concise review ENSG00000180210 ENSG00000003436 ENSG00000198734 PMC4303261__F6 Computational Approach to Identifying Gene-microRNA Modules in Cancer ENSG00000100234 ENSG00000282830 ENSG00000150093 ENSG00000137801 ENSG00000143387 ENSG00000105664 ENSG00000011422 ENSG00000154553 ENSG00000186340 ENSG00000038427 ENSG00000084636 ENSG00000083782 ENSG00000123342 ENSG00000078098 PMC4303261__F5 Computational Approach to Identifying Gene-microRNA Modules in Cancer ENSG00000087245 ENSG00000262635 ENSG00000148848 ENSG00000080573 ENSG00000143387 ENSG00000186340 ENSG00000134013 ENSG00000038427 ENSG00000291748 ENSG00000123342 ENSG00000106624 ENSG00000078098 ENSG00000143196 PMC9688668__F2 Targeting mTOR as a Cancer Therapy: Recent Advances in Natural Bioactive Compounds and Immunotherapy ENSG00000124102 ENSG00000169047 ENSG00000155792 PMC7766850__F8 Scheme of the effects of AMPAR antagonists on spontaneous seizure activity in epilepsy rats based on a previous and the present studies ENSG00000291971 PMC3837137__F6 A diverse range of signaling pathways that can lead to persistent PKC activation to support cell migration ENSG00000092871 ENSG00000157764 ENSG00000138798 ENSG00000136997 ENSG00000198670 PMC8507231__F1 Emerging roles of dysregulated adenosine homeostasis in brain disorders with a specific focus on neurodegenerative diseases ENSG00000156110 ENSG00000196839 PMC5359747__F1 Emerging therapeutic strategies to prevent infection-related microvascular endothelial activation and dysfunction ENSG00000154133 ENSG00000291971 ENSG00000172936 ENSG00000165527 PMC3843239__F7 Mechanism of myosin II–mediated release of microparticles from endothelial cells activated by antiB2GPI antibodies ENSG00000163914 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC8307395__F3 Two-Pore Channels Regulate Expression of Various Receptors and Their Pathway-Related Proteins in Multiple Ways ENSG00000147862 ENSG00000070831 ENSG00000111837 ENSG00000067900 ENSG00000117322 ENSG00000132676 PMC8708574__F4 CXCL13 in Cancer and Other Diseases: Biological Functions, Clinical Significance, and Therapeutic Opportunities ENSG00000002330 ENSG00000291971 ENSG00000170558 ENSG00000105723 PMC3148231__F12 MicroRNA 144 Impairs Insulin Signaling by Inhibiting the Expression of Insulin Receptor Substrate 1 in Type 2 Diabetes Mellitus ENSG00000110395 ENSG00000169047 PMC3224437__F4 Fatty acid biosynthesis model and pathway distance calculation method ENSG00000134824 ENSG00000149485 ENSG00000173599 ENSG00000099194 ENSG00000026103 PMC3355926__F1 Activation of the Pi3K/Tor pathway by insulin and glutamate ENSG00000102081 ENSG00000196712 PMC1899924__F8 Signaling pathways activated by mitogenic concentrations of TNFA and roles of furin, MT1-MMP, and MMP2 in the activation of the nSMase in mesenchymal cells ENSG00000087245 ENSG00000140564 PMC4837277__F1 Involvement of ROS in regulating M1 responsible phagocytic activity and inflammatory response ENSG00000150782 ENSG00000130159 ENSG00000175104 PMC6329517__F6 Impaired autophagic and mitochondrial functions are partially restored by ERT in Gaucher and Fabry diseases ENSG00000198793 ENSG00000112561 PMC4993159__F2 Hepcidin Regulation in the Anemia of Inflammation ENSG00000105697 ENSG00000168610 PMC6769473__F3 Genetic network and functions of PSGs (positively selected genes) related with the KEGG pathway of the PPAR signaling pathway, fat digestion and absorption, vitamin digestion and absorption ENSG00000125166 ENSG00000121207 ENSG00000166391 ENSG00000114113 ENSG00000167114 ENSG00000138823 ENSG00000099194 ENSG00000124253 ENSG00000123983 PMC4993159__F1 Hepcidin Regulation in the Anemia of Inflammation ENSG00000010704 ENSG00000187045 ENSG00000105697 ENSG00000168610 PMC10475367__F2 Kyoto Encyclopedia of Genes and Genomes pathway of target genes in CRC ENSG00000132906 ENSG00000117020 ENSG00000002330 ENSG00000157764 ENSG00000134982 ENSG00000113318 ENSG00000168036 ENSG00000095002 ENSG00000164305 PMC5709727__F7 TNF‐p100 pathway subverts noncanonical NF‐KB signaling in inflamed secondary lymphoid organs ENSG00000104856 ENSG00000111321 ENSG00000131323 ENSG00000127191 PMC5115901__F10 Plasticity Related Gene 3 (PRG3) overcomes myelin-associated growth inhibition and promotes functional recovery after spinal cord injury ENSG00000156575 ENSG00000198670 PMC2758233__F2 P75NTR-mediated signal transduction pathways ENSG00000177606 ENSG00000175104 PMC4340752__F1 UPR, autophagy and mitochondria crosstalk underlies the ER stress response ENSG00000152348 ENSG00000128272 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC7615304__F4 Germline and somatic mutations associated with primary aldosteronism ENSG00000163399 ENSG00000196557 ENSG00000138039 ENSG00000185231 ENSG00000179142 ENSG00000168036 ENSG00000088256 ENSG00000101558 PMC2225459__F2 Schema illustrating the effects of (a) metformin- or AICAR-induced AMPK activation, (b)adiponectin, and (c) TZDs or PPAR alpha ligands on the rat granulosa cell steroidogenesis ENSG00000159346 ENSG00000285070 ENSG00000140443 PMC5706455__F4 Red Carpet for Iron Metabolism ENSG00000121989 ENSG00000010704 ENSG00000106327 ENSG00000187045 ENSG00000178752 ENSG00000072274 ENSG00000168610 ENSG00000204217 PMC8924081__F4 G-protein coupled receptor 34 regulates the proliferation and growth of LS174T cells through differential expression of PI3K subunits and PTEN ENSG00000291971 PMC2276852__F7 Schematic representation of the proposed events triggered by exposure to replication inhibitors such as APH ENSG00000175054 ENSG00000197299 PMC3110730__F1 Wnt signaling and regulation of Beta-catenin in tumorigenesis ENSG00000005339 ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC5403405__F7 Proposed mechanism for oridonin-induced G2/M arrest and apoptosis in prostate cancer cells PMC7674641__F1 Metabolic pathways connected to protein prenylation ENSG00000131473 ENSG00000197429 ENSG00000113161 ENSG00000116237 PMC6771146__F3A Pituitary Transcriptional Response Related to Feed Conversion in Pigs ENSG00000118058 ENSG00000005339 ENSG00000172534 ENSG00000184634 ENSG00000099381 ENSG00000127616 ENSG00000139718 ENSG00000183495 PMC10778733__F3 Visualization of CAC-related genes and their functional cross-talks ENSG00000049323 ENSG00000162711 ENSG00000121807 ENSG00000122194 ENSG00000229314 ENSG00000064300 ENSG00000104368 ENSG00000115828 ENSG00000171720 ENSG00000126247 ENSG00000100170 ENSG00000136869 ENSG00000023445 ENSG00000104365 ENSG00000109320 ENSG00000109321 ENSG00000269335 ENSG00000173039 ENSG00000213341 ENSG00000006062 ENSG00000168610 ENSG00000087460 ENSG00000167522 ENSG00000110876 ENSG00000007171 ENSG00000132170 ENSG00000185652 ENSG00000100985 ENSG00000134243 ENSG00000096717 PMC4383151__F1 Metformin action to inhibit cancer ENSG00000291971 ENSG00000198793 PMC3670858__F1 Acetylsalicylic acid metabolic pathway ENSG00000066813 ENSG00000281857 PMC10778733__F7 PPI is related to adipocytokine signaling ENSG00000007171 ENSG00000132170 PMC12249733__F5 Involvement of the DEGs of NC and IC associated with effects of ACTH(6-9)PGP peptide a day after IR conditions in striatum ENSG00000070388 ENSG00000134215 ENSG00000158517 ENSG00000186818 ENSG00000173391 ENSG00000121966 ENSG00000150556 ENSG00000149968 ENSG00000263528 ENSG00000101438 ENSG00000058668 ENSG00000186297 ENSG00000157542 ENSG00000171189 ENSG00000011677 ENSG00000150594 ENSG00000156026 ENSG00000145040 ENSG00000007908 ENSG00000169860 ENSG00000276561 ENSG00000185386 ENSG00000173805 ENSG00000004948 ENSG00000113296 ENSG00000180616 ENSG00000181195 ENSG00000171608 ENSG00000145349 ENSG00000141655 PMC5910405__F1 Our multi-omics integrative analysis of the monolignol biosynthetic pathway in P ENSG00000009830 ENSG00000121807 PMC9336020__F1 Myricetin: targeting signaling networks in cancer and its implication in chemotherapy ENSG00000198793 ENSG00000136997 ENSG00000105697 ENSG00000198576 ENSG00000175104 ENSG00000168610 PMC5897502__F1 Antigen receptor signaling in naïve and anergic B cells PMC5819928__F1 EMT activation via TGFB ENSG00000169554 ENSG00000170558 ENSG00000288335 PMC7685798__F7 Reanalysis of 14 designated genes via KEGG pathway enrichment ENSG00000145604 ENSG00000108055 ENSG00000132646 ENSG00000136997 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000277273 PMC5519084__F5 Activation of aromatase promoter I.4 and promoters I.3/II in breast adipose fibroblasts and promoter I.7 in breast endothelial cells ENSG00000124102 ENSG00000168066 ENSG00000185591 ENSG00000179348 ENSG00000168610 ENSG00000160741 PMC8137893__F1 Immunomodulatory Effects of BRAF, MEK, and CDK4/6 Inhibitors: Implications for Combining Targeted Therapy and Immune Checkpoint Blockade for the Treatment of Melanoma ENSG00000157764 ENSG00000135446 ENSG00000105810 PMC6650552__F6 AnvM-mediated regulation and its interaction with host cell ENSG00000187554 ENSG00000125538 ENSG00000175104 PMC6136787__F4 Newborn blood DNA epigenetic variations and signaling pathway genes associated with Tetralogy of Fallot (TOF) ENSG00000065833 ENSG00000087842 PMC9632414__F1 Editorial: Dissection of the molecular basis of fatty acid composition in oil crops and molecular breeding of oil crops with improved fatty acid composition ENSG00000198670 ENSG00000062282 ENSG00000163788 ENSG00000026103 PMC4764103__F1 The CoA biosynthetic pathway ENSG00000138621 ENSG00000127125 PMC6878783__F2 Astaxanthin improves insulin sensitivity and glucose uptake ENSG00000169047 ENSG00000084733 ENSG00000119396 PMC5102108__F7 Hypothetical model of macrophage-to-Huh7 cell transmission of TLR3-induced anti-HCV activity by exosomes ENSG00000113360 ENSG00000164342 PMC6789757__F5 Mitogen-activated protein kinase (MAPK) signaling pathway and related miRNAs ENSG00000087095 ENSG00000170458 ENSG00000102871 ENSG00000117400 ENSG00000124733 ENSG00000143839 ENSG00000127191 ENSG00000026103 PMC3809754__F1 Biogenesis and function of microRNAs ENSG00000135473 ENSG00000128191 ENSG00000113360 ENSG00000242372 PMC10971110__F3 Immune response and gene expression through the NF-kB signaling pathway in sepsis ENSG00000174125 ENSG00000108691 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC4751587__F2 PI3K/AKT/mTOR signaling pathway and a proposed model for its regulation through the evaluated miRNAs ENSG00000065361 ENSG00000169047 ENSG00000198793 ENSG00000155792 PMC9289477__F1 Neonatal Innate Immune Response to Sepsis: Checkpoint Proteins as Novel Mediators of This Response and as Possible Therapeutic/Diagnostic Levers ENSG00000291603 ENSG00000213658 ENSG00000134982 ENSG00000010810 PMC8514054__F1 JAK-STAT pathway mutations and variants in human disease ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000173757 ENSG00000105639 ENSG00000168610 PMC5818603__F1 Chromatin structure of human and mouse telomeres ENSG00000166340 ENSG00000101945 ENSG00000187605 ENSG00000138336 ENSG00000080345 ENSG00000088305 ENSG00000143379 ENSG00000077514 ENSG00000180532 PMC9268676__F2 Current Advancements in Antitumor Properties and Mechanisms of Medicinal Components in Edible Mushrooms ENSG00000113520 PMC7387847__F10 Nrf2/SIKE-mediated hepatic injury induced by long-term PM2.5exposure ENSG00000183735 ENSG00000023909 ENSG00000079999 PMC7584080__F1 Pathway map highlighting all seven genes modified during this study in red ENSG00000090316 ENSG00000122966 ENSG00000172005 PMC7162985__F1 AKT-mTOR signaling pathway ENSG00000155792 PMC11700868__F1 Scheme of establishment and application of Nano-IFNG/Zole for remodeling the suppressive TIME induced by iRFA ENSG00000159128 ENSG00000111537 ENSG00000115415 ENSG00000197429 ENSG00000137265 ENSG00000112561 ENSG00000027697 ENSG00000118520 ENSG00000007171 PMC4034063__F1 Core hypothalamic energy homeostatic circuit and the dopamine reward pathway ENSG00000198576 ENSG00000115138 ENSG00000166603 PMC3728801__F1 Canonical and non-canonical NFKB pathways ENSG00000104856 ENSG00000148798 ENSG00000173039 PMC8809547__F2 EBV-driven 1C pathway drives nucleotide and glutathione synthesis ENSG00000065911 ENSG00000100714 ENSG00000092621 ENSG00000164466 ENSG00000135069 ENSG00000146733 ENSG00000164933 ENSG00000120254 PMC12003768__F5 Studying the efficacy of JBOL volatile components in idiopathic pulmonary fibrosis (IPF) using GC-MS and network pharmacology ENSG00000163464 ENSG00000157404 ENSG00000117298 ENSG00000143839 ENSG00000108443 ENSG00000171791 ENSG00000121807 ENSG00000239732 ENSG00000188257 ENSG00000001626 ENSG00000275565 ENSG00000077782 ENSG00000140443 ENSG00000262406 ENSG00000100448 ENSG00000131747 ENSG00000007908 ENSG00000102468 ENSG00000007171 ENSG00000132170 ENSG00000138735 ENSG00000138207 ENSG00000274247 ENSG00000136960 ENSG00000162438 ENSG00000169397 ENSG00000151617 ENSG00000162692 ENSG00000146648 ENSG00000151490 ENSG00000065989 ENSG00000070831 ENSG00000291971 ENSG00000181104 ENSG00000113161 ENSG00000255974 ENSG00000165280 ENSG00000169032 ENSG00000121879 ENSG00000164305 ENSG00000122194 ENSG00000158125 ENSG00000104368 ENSG00000179295 ENSG00000163631 ENSG00000180210 ENSG00000277571 ENSG00000133019 ENSG00000117525 ENSG00000149968 ENSG00000196549 ENSG00000125538 ENSG00000137672 ENSG00000037280 ENSG00000148346 ENSG00000133895 ENSG00000137673 ENSG00000157764 ENSG00000116044 ENSG00000160013 ENSG00000109320 ENSG00000163220 ENSG00000086991 ENSG00000133063 ENSG00000168487 ENSG00000140465 ENSG00000073756 ENSG00000168610 ENSG00000145321 ENSG00000134853 ENSG00000164362 ENSG00000164690 ENSG00000100985 ENSG00000005381 PMC4754612__F1 Stimulator of interferon genes (STING)‐mediated cytosolic DNA sensing pathway ENSG00000183735 ENSG00000164430 ENSG00000105612 ENSG00000159461 PMC9693028__F3 Antioxidant Properties of Hemp Proteins: From Functional Food to Phytotherapy and Beyond ENSG00000125538 ENSG00000079999 PMC9901261__F1 Emerging role of triggering receptor expressed on myeloid cell-2 in malignant tumor ENSG00000291971 ENSG00000137845 PMC6618772__F1 Simplified metabolism of thiopurines in a target cell ENSG00000042832 ENSG00000137364 ENSG00000167701 PMC9656488__F2 DNA Repair Mechanisms, Protein Interactions and Therapeutic Targeting of the MRN Complex ENSG00000149311 ENSG00000175054 ENSG00000149554 ENSG00000183765 PMC8071014__F2 Glucose and lipid metabolism in TAMs ENSG00000135218 ENSG00000118520 PMC7017203__F4 ING proteins are involved in the DNA Damage Response ENSG00000149311 ENSG00000012048 ENSG00000153487 ENSG00000168395 ENSG00000112130 PMC4795487__F5 KEGG pathway analysis., The integrated pathway showing the interactions of differentially expressed proteins in apoptotic and survival pathways ENSG00000149311 ENSG00000132906 ENSG00000291983 ENSG00000002330 ENSG00000102871 ENSG00000164399 ENSG00000168040 ENSG00000127191 ENSG00000164305 PMC8800112__F3 New blood-based RNA signature (R9), for monitoring effectiveness of tuberculosis treatment in a South Indian longitudinal cohort ENSG00000168062 ENSG00000142192 ENSG00000115884 ENSG00000138772 ENSG00000109654 ENSG00000132478 ENSG00000100985 ENSG00000127948 PMC8899158__F9 CTNNAL1 participates in the regulation of mucus overproduction in HDM‐induced asthma mouse model through the YAP‐ROCK2 pathway ENSG00000291363 ENSG00000113520 PMC2577004__F1 Oncogenic NOTCH1 control of MYC and PI3K: challenges and opportunities for anti-NOTCH1 therapy in T-ALL ENSG00000283780 ENSG00000148400 ENSG00000198793 ENSG00000136997 ENSG00000114315 ENSG00000109670 PMC3085544__F1 Intracellular signaling by the leptin (LepRb - cyan) and insulin receptor (magenta) ENSG00000168610 PMC8786676__F3 Deep models of integrated multiscale molecular data decipher the endothelial cell response to ionizing radiation ENSG00000108691 ENSG00000113140 ENSG00000136997 ENSG00000026508 ENSG00000171791 PMC8739787__F2 HIF-1A Is a Rational Target for Future Ovarian Cancer Therapies ENSG00000087245 ENSG00000134086 ENSG00000198793 ENSG00000170145 ENSG00000106236 ENSG00000100985 ENSG00000168610 PMC11172598__F1 Gene interaction network map of each group ENSG00000151657 ENSG00000128918 PMC9131029__F2 Plasmalogens and Photooxidative Stress Signaling in Myxobacteria, and How it Unmasked CarF/TMEM189 as the Δ1′-Desaturase PEDS1 for Human Plasmalogen Biosynthesis ENSG00000018510 ENSG00000116906 ENSG00000197601 ENSG00000240849 ENSG00000133027 PMC12021866__F7 Baicalein ameliorates cognitive decline induced by chronic cerebral hypoperfusion through the SIRT1-mediated Notch1 pathway to improve angiogenesis and suppress neuroinflammation ENSG00000128917 ENSG00000148400 ENSG00000096717 ENSG00000114315 PMC9360701__F2 Hypothesized neuroprotective effect of minocycline against COVID-19-induced stroke and neurological dysfunction: possible role of matrix metalloprotease signaling pathway ENSG00000087245 ENSG00000140564 ENSG00000149968 ENSG00000157227 ENSG00000125538 ENSG00000100985 ENSG00000122194 PMC6678131__F6 Role of LOXL3 in tumor ENSG00000008710 ENSG00000115318 ENSG00000196591 ENSG00000051180 ENSG00000095002 ENSG00000139618 PMC2706143__F3 Endoplasmic Reticulum and the Unfolded Protein Response ENSG00000132906 ENSG00000291983 ENSG00000128272 ENSG00000127191 ENSG00000164305 PMC4452354__F1 Schematic illustration of the transduction of signals from inflammatory bone diseases to brain-resident microglia through the leptomeninges and two different pathways for the IL-1B production activated by CGA and AB in microglia ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC4054417__F3 Distinct regulation of apoptosis pathway genes in neurons and fibroblasts in response to VZV infection ENSG00000282905 ENSG00000102871 ENSG00000172936 ENSG00000151929 ENSG00000120868 ENSG00000171791 ENSG00000168040 ENSG00000127191 PMC4817280__F2 Partial biosynthesis pathway for major brain gangliosides ENSG00000111728 ENSG00000115525 PMC2706143__F2 The Endoplasmic Reticulum and the Unfolded Protein Response ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC3565264__F4A Quantitative Profiling of DNA Damage and Apoptotic Pathways in UV Damaged Cells Using PTMScan Direct ENSG00000149311 ENSG00000175054 ENSG00000157927 ENSG00000132646 ENSG00000197299 ENSG00000105402 ENSG00000126458 PMC8786676__F6 Deep models of integrated multiscale molecular data decipher the endothelial cell response to ionizing radiation ENSG00000026508 PMC3017607__F2 The kinetic framework for programmed –1 ribosomal frameshifting ENSG00000127948 PMC5006677__F1 The Akt/mTORC1 signaling pathway leading to accelerated translation and increased protein synthesis ENSG00000169047 PMC6101557__F1 Inflammatory caspases (caspase-1 and caspase-4/5/11) are activated through canonical or non-canonical inflammasomes, triggered by microorganism infection ENSG00000150782 ENSG00000163568 ENSG00000125538 PMC2374589__F1 Programmed cell death can be executed via extrinsic and intrinsic pathways depending on the stimulus leading to apoptosis ENSG00000115317 PMC7432699__F7 Schematic summary of the miR-targeting of RSU1 ENSG00000148484 PMC8306961__F3 Arginine Signaling and Cancer Metabolism ENSG00000128272 ENSG00000102034 ENSG00000116688 ENSG00000198793 ENSG00000197905 ENSG00000070669 PMC8306961__F2 Arginine Signaling and Cancer Metabolism ENSG00000177058 ENSG00000173612 PMC7935942__F5 Expanding the drug discovery space with predicted metabolite–target interactions ENSG00000149782 ENSG00000112115 ENSG00000179921 PMC8306961__F6 Arginine Signaling and Cancer Metabolism ENSG00000167601 ENSG00000108691 ENSG00000157764 ENSG00000198793 ENSG00000136997 ENSG00000121807 ENSG00000168610 ENSG00000010671 PMC2578840__F8 Proposed signaling pathway PMC6637848__F9 L-proline-mediated differentiation of mESCs to EPL cells ENSG00000128272 ENSG00000144895 ENSG00000198793 PMC6637848__F7 Cell signalling events that mediate the switch between self-renewal and differentiation in mouse embryonic stem cells ENSG00000198793 ENSG00000128342 ENSG00000168610 ENSG00000125968 PMC3798256__F1 Pathways involved in stem cell hemostasis via regulation of nutrient sensing ENSG00000096717 PMC3089033__F8 Diagram of the proposed cell survival signaling pathway in ER+ breast cancer cells with PI3KCA mutations and low phosphorylated Akt ENSG00000002330 ENSG00000284571 PMC6836728__F5 Schematic representation of the proposed intracellular trafficking pathways of NPRA through the multi-organelle systems in cell compartments: ENSG00000145321 PMC5037386__F5 Gene expression profiling reveals aryl hydrocarbon receptor as a possible target for photobiomodulation when using blue light ENSG00000102871 ENSG00000291971 ENSG00000140505 ENSG00000140465 ENSG00000146648 ENSG00000106546 ENSG00000079999 PMC2869518__F3 Proximal signaling events in the TCR-coupled signaling pathway ENSG00000213658 ENSG00000070831 PMC8329526__F2 Context-Dependent Roles of Claudins in Tumorigenesis ENSG00000159216 ENSG00000105397 ENSG00000119888 ENSG00000134982 ENSG00000276463 ENSG00000136997 ENSG00000114315 ENSG00000134548 PMC5823598__F1 Preclinical evaluation of the PI3K/Akt/mTOR pathway in animal models of multiple sclerosis ENSG00000171723 ENSG00000104142 ENSG00000108443 ENSG00000164327 ENSG00000141564 ENSG00000006715 ENSG00000115207 ENSG00000083750 ENSG00000100290 ENSG00000134371 ENSG00000046889 ENSG00000128052 ENSG00000112578 ENSG00000179632 ENSG00000145782 ENSG00000198947 ENSG00000119487 ENSG00000005882 ENSG00000173156 ENSG00000155876 ENSG00000132478 ENSG00000025039 ENSG00000112079 ENSG00000129460 ENSG00000132356 ENSG00000115956 ENSG00000162409 PMC7563273__F1 The activation and regulation of the PI3K/Akt/mTOR signaling pathway ENSG00000169047 ENSG00000155792 PMC3317163__F2 One-carbon metabolism ENSG00000214435 ENSG00000116984 PMC7563273__F3 Targeting the PI3K/Akt/mTOR pathway in AML ENSG00000169047 PMC9447342__F7 CircPRKCH modulates extracellular matrix formation and metabolism by regulating the miR-145/HGF axis in osteoarthritis ENSG00000019991 ENSG00000149968 PMC4712330__F3 PTEN tumor suppressor gene and its role in lymphoma pathogenesis ENSG00000069869 ENSG00000145241 ENSG00000169047 ENSG00000198793 ENSG00000051180 ENSG00000132341 PMC4367908__F2 The network of molecules involved in the control of VPC fate determination and the cell cycle in C ENSG00000134982 ENSG00000135446 ENSG00000140598 ENSG00000123374 PMC4712330__F4 PTEN tumor suppressor gene and its role in lymphoma pathogenesis ENSG00000177455 ENSG00000198793 ENSG00000198286 PMC8909472__F2 Direct Targeting KRAS Mutation in Non-Small Cell Lung Cancer: Focus on Resistance ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC7684877__F6 Putative mechanism by which metabolite secretions of L ENSG00000087245 ENSG00000100985 ENSG00000112715 PMC7873381__F1 ZBTB20 regulates WNT/CTNNB1 signalling pathway by suppressing PPARG during hepatocellular carcinoma tumourigenesis ENSG00000134982 ENSG00000168036 ENSG00000132170 PMC11354764__F3 Three main UPR pathways induced by ER stress ENSG00000128272 ENSG00000144895 ENSG00000169047 PMC11354764__F2 Main pathways involved in the development of insulin resistance ENSG00000169047 ENSG00000177606 ENSG00000172936 ENSG00000115290 PMC11354764__F1 Insulin signaling pathway ENSG00000002330 ENSG00000110395 ENSG00000169047 PMC12111366__F1 Hemp iron plays a role in muscle regeneration, lipid metabolism, and cholesterol management ENSG00000010704 ENSG00000106327 PMC3885992__F5 Polarization of immune cells in the tumour environment by TGFB PMC8125586__F3 Psoriasis: From Pathogenesis to Pharmacological and Nano-Technological-Based Therapeutics ENSG00000111012 ENSG00000019186 ENSG00000186104 PMC7815509__F1 Oligodendrocyte lineage cells and depression ENSG00000148400 ENSG00000197971 ENSG00000173599 ENSG00000134853 ENSG00000205927 ENSG00000100146 ENSG00000166164 ENSG00000237834 PMC3757382__F1 Modified Fearson and Volgenstein Model ENSG00000157764 ENSG00000134982 PMC4529978__F1 ROS-dependent cellular senescence pathways in MSCs ENSG00000088305 ENSG00000096717 PMC3443885__F3 Molecular interaction between estrogen and thyroid hormone ENSG00000115415 ENSG00000291971 PMC3930904__F1 Global view on the intracellular proteome profile change in P ENSG00000074800 ENSG00000138356 PMC7143281__F4 Tricarboxylic acid (TCA) cycle showing differences in gene expression and metabolite abundances in mouse liver ENSG00000067992 ENSG00000073578 ENSG00000117118 ENSG00000005882 ENSG00000105953 ENSG00000172340 ENSG00000131828 ENSG00000101365 ENSG00000143252 ENSG00000163114 ENSG00000100412 ENSG00000110435 ENSG00000146701 ENSG00000091140 ENSG00000062485 PMC4595469__F7 Contrasting Effects of the Cytotoxic Anticancer Drug Gemcitabine and the EGFR Tyrosine Kinase Inhibitor Gefitinib on NK Cell-Mediated Cytotoxicity via Regulation of NKG2D Ligand in Non-Small-Cell Lung Cancer Cells ENSG00000231179 ENSG00000204520 ENSG00000146648 PMC7564814__F2 Intracellular cytoplasmic pattern-recognition receptor RIG-I is essential for the control of RNA virus infection ENSG00000162711 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000121060 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC11696735__F5 Biosynthetic pathway of steroidal saponins in P ENSG00000116133 ENSG00000172893 ENSG00000149809 PMC9203969__F1 NRF2 in Fibrotic Diseases: From Mechanisms to Therapeutic Approaches ENSG00000079999 PMC4369322__F1 A model for the integral role of the Rad6 DNA damage tolerance pathway in coordinating the activities of Fanconi anemia (FA) network and homologous recombination repair (HRR) pathway in interstrand DNA crosslink (ICL) repair ENSG00000012048 ENSG00000144554 ENSG00000132646 ENSG00000115392 ENSG00000070950 ENSG00000051180 ENSG00000139618 PMC3714590__F5 Known and Predicted Interactions between the Products of the 352 Genes Bound Preferentially by Pol II in Neuroepithelial CellsAnalysis was performed using STRING with a medium confidence score of 0.4 and all interaction methods available ENSG00000125166 ENSG00000087245 ENSG00000173992 ENSG00000163914 ENSG00000138606 ENSG00000185269 ENSG00000146648 ENSG00000076604 ENSG00000124827 PMC11950302__F8 Simultaneous targeted delivery of doxorubicin and KRAS suppression by a hybrid molecule containing miR-143 and AS1411 aptamer PMC2782644__F5 Differentiating Human Multipotent Mesenchymal Stromal Cells Regulate microRNAs ENSG00000110395 ENSG00000105329 ENSG00000172534 ENSG00000109320 ENSG00000136997 ENSG00000134853 ENSG00000168610 ENSG00000106546 PMC11975384__F1 Comprehensive examination of the Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5239825__F4 NRF2 as a hub connecting proteotoxic-derived emergency signals to a protective transcriptional response ENSG00000177169 ENSG00000103035 ENSG00000066739 ENSG00000023909 ENSG00000164294 ENSG00000057663 ENSG00000079999 ENSG00000185627 ENSG00000095261 ENSG00000159352 ENSG00000108671 ENSG00000173692 ENSG00000256646 ENSG00000132963 ENSG00000041357 PMC7178451__EV1 STAT3‐dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer ENSG00000134086 ENSG00000111537 ENSG00000148798 ENSG00000131095 PMC6304530__F1 The reprogramming of metabolism in cancer ENSG00000198793 ENSG00000136997 ENSG00000115419 PMC6982088__F1 Cyclic production of melatonin, from external (e.g., pineal and possibly extrapineal sources) or internal uterine sources, is responsible for promoting decidualization and improving implantation ENSG00000113070 ENSG00000128342 ENSG00000266524 ENSG00000163501 ENSG00000073756 ENSG00000178568 ENSG00000130513 PMC3689263__F2 Signaling mechanisms important for endocrine resistance and which are currently targeted in clinical trials, combined with aromatase inhibitors ENSG00000291971 ENSG00000135446 ENSG00000138798 PMC8619591__F1 Bridging Radiotherapy to Immunotherapy: The IFN–JAK–STAT Axis ENSG00000159128 ENSG00000213928 ENSG00000105397 ENSG00000198793 ENSG00000027697 ENSG00000125347 ENSG00000142166 PMC5339807__F4 Sequential activation of different pathway networks in ischemia-affected and non-affected myocardium, inducing intrinsic remote conditioning to prevent left ventricular remodeling ENSG00000196549 ENSG00000120885 ENSG00000159399 PMC3353781__F8 Signaling pathways mediating Beta-adrenergic effects on the cardiac microtubule network ENSG00000149269 ENSG00000047849 PMC2911442__F5 WRN participates in the regulation of PCNA mono-ubiquitination and subsequent TLS through interaction with PCNA ENSG00000149311 ENSG00000132646 ENSG00000165392 ENSG00000070950 PMC7372553__F9 CTNND1 function in systemic disease ENSG00000168036 PMC7004516__F3 Association of efficacy of 5‐fluorouracil (5‐FU) and metabolic changes in cultured colorectal cancer cells ENSG00000131473 ENSG00000197713 ENSG00000067057 ENSG00000117118 ENSG00000153574 ENSG00000163541 ENSG00000120437 ENSG00000101365 ENSG00000173599 ENSG00000164398 ENSG00000146701 ENSG00000091140 ENSG00000152556 PMC5541032__F3 Antibody-dependent enhancement (ADE) of Zika virus (ZIKV) and strategies to limit it ENSG00000115415 PMC6491625__F5 Network analysis of Ly6D, Ly6E, Ly6K, and Ly6H genes ENSG00000139193 ENSG00000198851 ENSG00000278032 ENSG00000135903 ENSG00000175592 ENSG00000112715 ENSG00000131126 ENSG00000106546 ENSG00000163631 ENSG00000095585 ENSG00000167656 ENSG00000111537 ENSG00000274488 ENSG00000172216 ENSG00000177606 ENSG00000160886 PMC4465499__F4 Plasma Proteomic Profiling in Hereditary Breast Cancer Reveals a BRCA1-Specific Signature: Diagnostic and Functional Implications ENSG00000284774 ENSG00000170430 ENSG00000171560 ENSG00000102977 PMC4556940__F8 Network representation of microRNA ENSG00000121989 ENSG00000152661 ENSG00000105329 ENSG00000123454 ENSG00000175592 ENSG00000064300 ENSG00000117054 ENSG00000095303 ENSG00000177674 ENSG00000120251 ENSG00000171885 ENSG00000131473 ENSG00000090104 ENSG00000050628 ENSG00000091972 ENSG00000100994 ENSG00000086991 ENSG00000110680 ENSG00000117152 ENSG00000073756 ENSG00000285456 ENSG00000226275 ENSG00000125675 ENSG00000177606 ENSG00000106853 ENSG00000028137 ENSG00000136689 ENSG00000167186 PMC4465499__F3 Plasma Proteomic Profiling in Hereditary Breast Cancer Reveals a BRCA1-Specific Signature: Diagnostic and Functional Implications ENSG00000224320 ENSG00000150991 ENSG00000166278 ENSG00000181026 ENSG00000171560 PMC8889667__F1 Targeting PD-1/PD-L1 pathway in myelodysplastic syndromes and acute myeloid leukemia ENSG00000163220 ENSG00000136997 PMC3100722__F1 The neuroendocrine (a), limbic (b), and brainstem (c) inter-related, stress-activated corticotropin releasing hormone (CRH) loops ENSG00000164879 PMC8266859__F8 Possible role of BA3/A1-crystallin in the EGFR signaling network and RPE polarity ENSG00000197713 ENSG00000146648 ENSG00000108255 PMC8889667__F2 Targeting PD-1/PD-L1 pathway in myelodysplastic syndromes and acute myeloid leukemia ENSG00000091972 ENSG00000136869 ENSG00000118971 PMC9687343__F5 Cancer Metastasis and Treatment Resistance: Mechanistic Insights and Therapeutic Targeting of Cancer Stem Cells and the Tumor Microenvironment ENSG00000168036 PMC6561919__F7 ATR mediates cisplatin resistance in 3D-cultured breast cancer cells via translesion DNA synthesis modulation ENSG00000175054 ENSG00000132646 ENSG00000009413 PMC9687343__F4 Cancer Metastasis and Treatment Resistance: Mechanistic Insights and Therapeutic Targeting of Cancer Stem Cells and the Tumor Microenvironment ENSG00000281324 ENSG00000130234 ENSG00000198793 ENSG00000168036 PMC7078475__F1 Biochemical pathways involved in central carbon catabolism in P ENSG00000090316 ENSG00000074800 ENSG00000073578 ENSG00000122966 ENSG00000117118 ENSG00000172005 ENSG00000094975 PMC8566972__F3 Ku70 as a Cytosolic DNA Sensor in Innate Immunity and Beyond ENSG00000143799 ENSG00000183735 ENSG00000111537 ENSG00000198793 ENSG00000125347 ENSG00000276561 PMC3733021__F1 Schematic diagram of the ZFN, TALEN, and CRISPR/Cas9 genome editing tools ENSG00000089692 ENSG00000181847 ENSG00000134982 PMC8634046__F7 Histone deacetylase 5 deacetylates the phosphatase PP2A for positively regulating NFKB signaling ENSG00000108840 PMC3829921__F1 Small GTPases as regulators of cell division ENSG00000080371 ENSG00000165527 ENSG00000111737 PMC1904229__F12 Schematic model of Zfra/WOX1 involvement in TNF signaling ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC6907041__F7 PBR-BuOH suppressed IgE/Ag-mediated allergic responses that are initiated by FcERI signaling pathway ENSG00000033327 ENSG00000010810 PMC7694686__F1 Summary of MEMO1′s role in a variety of signaling pathways, including the: (A) ERBB-family, (B) FGFR-family, (C) IGF1R-family, (D) estrogen receptor and (E) PDGFR and S1P/S1PR families ENSG00000163539 ENSG00000291971 ENSG00000134982 ENSG00000140443 PMC8533565__F1 Virus-Induced Tumorigenesis and IFN System ENSG00000198793 ENSG00000166750 ENSG00000099942 ENSG00000168610 ENSG00000276561 ENSG00000239732 ENSG00000164430 ENSG00000184995 ENSG00000105397 ENSG00000115415 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC2764428__F4 MiRNA/TF-mediated regulatory pathway associated with tumorigenesis ENSG00000037965 ENSG00000112242 ENSG00000136997 ENSG00000137203 ENSG00000135903 ENSG00000112182 ENSG00000168610 PMC9259489__F3 Intestinal epithelial cell mitochondria serve as metabolic signaling platform translating microbiome-derived signals into mucosal responses ENSG00000162711 ENSG00000108179 ENSG00000088888 ENSG00000167207 ENSG00000197375 ENSG00000237693 ENSG00000130159 ENSG00000175104 PMC2559887__F3 Ingenuity pathway analysis on NFKB related gene network ENSG00000128016 ENSG00000105516 ENSG00000113140 ENSG00000099860 ENSG00000119681 ENSG00000137801 ENSG00000157184 ENSG00000261371 ENSG00000186010 ENSG00000082512 ENSG00000175899 ENSG00000130222 ENSG00000281500 PMC2559887__F2 Ingenuity pathway analysis on AP-1 related gene network ENSG00000159921 ENSG00000126858 ENSG00000163947 ENSG00000111057 ENSG00000127184 ENSG00000130522 ENSG00000159388 ENSG00000132478 ENSG00000124664 ENSG00000076662 PMC3541122__F6 MiR-29 family is involved in multiple cellular processes ENSG00000115415 ENSG00000105810 PMC9277821__F2 Emerging roles of circular RNAs in gastric cancer metastasis and drug resistance ENSG00000103266 ENSG00000134982 ENSG00000168036 ENSG00000112715 ENSG00000136231 ENSG00000104814 ENSG00000134086 ENSG00000136997 ENSG00000150907 ENSG00000088247 ENSG00000145321 ENSG00000136504 ENSG00000026508 PMC5645395__F6 Illustration of the cooperative regulation of a miRNA module that contains four miRNAs: miR-18a-3p, -320a, -193b-3p, and -92b-3p (pink diamonds) ENSG00000107263 ENSG00000002330 ENSG00000129946 ENSG00000149269 ENSG00000010810 ENSG00000130402 ENSG00000137076 ENSG00000186111 ENSG00000160293 ENSG00000138964 ENSG00000130669 ENSG00000136068 PMC5645395__F5 MiRNA-mediated gene regulation involved in two functional pathways in the early stage of KIRC and KIRP (miRNAs: pink diamonds; genes: ellipses) ENSG00000149311 ENSG00000101972 ENSG00000005339 ENSG00000136997 PMC9607910__F1 Applications of Exosomes in Diagnosing Muscle Invasive Bladder Cancer ENSG00000164362 ENSG00000139687 PMC5693858__F10 A schematic of the mechanism of Panax notoginseng root (PNR) in its enhancing of antiviral interferon-mediated immune responses and natural killer (NK) cell activity ENSG00000183735 ENSG00000105397 ENSG00000115415 PMC4498560__F1 HPVs infect host epithelial cells (keratinocytes) by interacting with different cell surface receptors such as integrin and heparan sulfate proteoglycans (HSPGs) ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC5966753__F7 Action of testosterone (T) in inducing hepatic steatosis/steatohepatitis ENSG00000042832 ENSG00000144895 ENSG00000285482 ENSG00000100219 ENSG00000127191 ENSG00000026103 PMC4108232__F1 Mitochondrial dysfunctions in cancer ENSG00000062485 PMC3583171__F3 Significantly differentially expressed genes identified by KEGG as involved in toll-like receptor signaling ENSG00000170458 ENSG00000198517 ENSG00000168040 ENSG00000150455 PMC9326066__F2 Single-Cell Metabolomics in Hematopoiesis and Hematological Malignancies ENSG00000135218 ENSG00000070669 ENSG00000115419 ENSG00000159399 ENSG00000026103 PMC5430701__F1 Chemokine signalling pathway (source-http://www.kegg.jp/kegg/kegg1.html) ENSG00000169291 ENSG00000113263 PMC7361144__F3 Type I interferon pathway during SARS‐CoV infection and modulatory mechanisms, PLpro excluded ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000115415 ENSG00000131323 ENSG00000175104 PMC3917856__F6 NRF2-KEAP1 Pathway Is an Early Responsive Gene Network in Arsenic Exposed Lymphoblastoid Cells ENSG00000166794 ENSG00000128272 ENSG00000177606 ENSG00000167996 ENSG00000165280 ENSG00000115657 ENSG00000125656 ENSG00000176153 ENSG00000023909 ENSG00000135624 ENSG00000138356 ENSG00000101557 PMC10258460__F1 Novel Metabolic Detour for Pancreatic Cancer Survival ENSG00000116649 ENSG00000102172 PMC7774460__F2 RT induces local immunogenic effects ENSG00000111537 ENSG00000158825 PMC7748218__F6 Model showing contribution of CXCR6-CXCL16 axis in overcoming the effect of DTX: ENSG00000002330 ENSG00000105329 ENSG00000161921 ENSG00000138798 ENSG00000154059 ENSG00000168036 ENSG00000137845 ENSG00000168610 PMC6288349__F7 Signaling in HIV-1-mediated inflammation ENSG00000162711 ENSG00000125538 ENSG00000121966 PMC9213747__F2 Malignant Myeloid Leukemia by Mesenchymal Stem Cells ENSG00000178860 ENSG00000167601 ENSG00000019582 ENSG00000105329 ENSG00000163739 ENSG00000125538 ENSG00000198576 ENSG00000168036 ENSG00000162692 ENSG00000154188 PMC9637482__F8 Cigarette smoke-promoted increases in osteopontin expression attract mesenchymal stem cell recruitment and facilitate lung cancer metastasis ENSG00000178860 ENSG00000026508 ENSG00000168610 PMC12124685__F11 HIV-1 infection stages, deregulated miRNAs, targeted hub genes, and principal enriched signaling pathways in macrophages ENSG00000198793 PMC5979540__F7 Signalling pathways regulating pluripotency of stem cells regulated by detected differentially expressed miRNAs depend on muscle mass ENSG00000123999 ENSG00000178860 ENSG00000134982 ENSG00000167074 PMC5979540__F6 Hippo signalling pathway identified as the most regulated by detected differentially expressed miRNAs depends on muscle mass ENSG00000129474 ENSG00000004975 ENSG00000124102 ENSG00000126016 ENSG00000109321 ENSG00000134982 ENSG00000136997 ENSG00000139926 ENSG00000081051 ENSG00000132535 ENSG00000116962 ENSG00000140807 PMC6203874__F1 Cholesterol-dependent cytolysin ENSG00000160752 ENSG00000152904 ENSG00000113161 PMC4621609__F10 Schematic of a proposed model for GLP1-mediated signaling pathway protecting cardiomyocytes from PA-induced lipotoxicity ENSG00000135218 ENSG00000168036 ENSG00000171791 PMC5130051__F2 Engineered nanoparticles induce cell apoptosis: potential for cancer therapy ENSG00000168040 ENSG00000096717 ENSG00000026103 PMC4747889__F3 Highest confidence network constructed with differentially methylated genes by proton beam treatment on the MCF-7 cell ENSG00000173163 ENSG00000115163 ENSG00000060138 ENSG00000197045 ENSG00000148484 ENSG00000168256 ENSG00000102710 ENSG00000119048 ENSG00000086827 ENSG00000270800 ENSG00000137947 ENSG00000278023 ENSG00000182504 ENSG00000288475 ENSG00000146411 ENSG00000126458 ENSG00000281500 ENSG00000117305 PMC7847386__F1 Nucleic acid-sensing pathways and their evasion by SARS-CoV-2 during COVID-19 infection ENSG00000278718 ENSG00000162711 ENSG00000183735 ENSG00000111405 ENSG00000164430 ENSG00000088888 ENSG00000130234 ENSG00000125538 ENSG00000172936 ENSG00000107201 ENSG00000276561 ENSG00000164342 PMC12190939__F2 Roles of DDR1 in tumor immunology PMC8950262__F1 Tissue-Specific Expression of the Terpene Synthase Family Genes in Rosa chinensis and Effect of Abiotic Stress Conditions ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC5948768__F12 ATP6AP2-induced neural differentiation ENSG00000069482 ENSG00000182220 ENSG00000131095 PMC7815874__F1 Increasing glycolysis by deletions of kcs1 and arg82 improved SAM production in Saccharomyces cerevisiae ENSG00000133116 PMC4654653__F2 Implications of microbiota and bile acid in liver injury and regeneration ENSG00000198610 ENSG00000180432 ENSG00000099377 ENSG00000115271 ENSG00000122787 ENSG00000135929 PMC7695834__F8 Borax induces osteogenesis by stimulating NaBC1 transporter via activation of BMP pathway ENSG00000107779 ENSG00000170365 PMC4397621__F1 Schematic model of novel inhibitors in Fas-associated death domain-Procaspase 8 interaction and Caspase 3 activation via Caspase 8 ENSG00000102871 ENSG00000168040 PMC7441375__F9 Action of MPA ENSG00000163914 ENSG00000145321 ENSG00000132915 PMC1779657__F2 Recent observations on the regulation of fetal metabolism by glucose PMC5286961__F1 A scheme of the mutant p53–Nrf2–proteasome pathway with chemotherapeutic intervention targeted at mutant p53 and the proteasome ENSG00000157764 ENSG00000079999 PMC6556055__F10 Schematic diagram of mechanism on this research ENSG00000181019 ENSG00000178573 ENSG00000125538 ENSG00000079999 PMC6073315__F1 Schematic illustration of hypothalamic regulation of energy homeostasis ENSG00000198793 ENSG00000173599 ENSG00000198576 ENSG00000115138 ENSG00000170893 ENSG00000166603 PMC9329830__F1 Adipokines, Hepatokines and Myokines: Focus on Their Role and Molecular Mechanisms in Adipose Tissue Inflammation ENSG00000148346 ENSG00000138207 ENSG00000197635 ENSG00000113140 ENSG00000130513 PMC3224806__F1 Deciphering the role of Th17 cells in human disease ENSG00000169245 ENSG00000111537 ENSG00000134982 ENSG00000138755 PMC6978354__F6 Differential methylation of genes in the B-cell receptor signalling pathway ENSG00000070190 ENSG00000104365 ENSG00000105369 ENSG00000100906 ENSG00000109320 ENSG00000269335 ENSG00000185885 ENSG00000213341 ENSG00000121879 ENSG00000100485 ENSG00000117322 ENSG00000010671 ENSG00000177455 ENSG00000095585 ENSG00000166501 ENSG00000197943 ENSG00000160293 PMC7855922__F1 PI3K Driver Mutations: A Biophysical Membrane-Centric Perspective ENSG00000157764 ENSG00000198793 PMC6139279__F1 ROS signaling and ER stress in cardiovascular disease ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC6330712__F3 Simplified pathway for the synthesis of the GPI-core (based on Cardoso et al., ) ENSG00000000419 ENSG00000100564 ENSG00000136908 PMC12245687__F6 Mechanism of the Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8867516__F1 Rare Autoinflammatory Diseases ENSG00000183735 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC12245687__F8 Schematic diagram summarizing the mechanisms of intestinal signaling pathways ENSG00000278718 ENSG00000162711 ENSG00000239732 ENSG00000198793 ENSG00000163914 ENSG00000172936 ENSG00000136869 ENSG00000067900 ENSG00000175104 PMC12245687__F7 Mechanism of the Nrf2 signaling pathway ENSG00000189403 ENSG00000079999 PMC12245687__F4 Mechanism of Rho/Rock signaling pathway ENSG00000163914 ENSG00000067900 PMC6073797__F9 Mechanisms underlying the effects of Stachys sieboldii (SS) PMC12245687__F3 Signaling pathway mechanism of TLRs ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC8714987__F8 Endothelial upregulation of mechanosensitive channel Piezo1 in pulmonary hypertension ENSG00000148400 ENSG00000074181 ENSG00000103335 PMC3246295__F2 Gab2 interactions with binding partners PMC5411014__F3 Pathophysiology and management of CVD ENSG00000039537 ENSG00000166278 ENSG00000162692 PMC5228698__F1 Diagram of genes in the PI3K/AKT signaling pathway ENSG00000140992 ENSG00000131482 ENSG00000058085 ENSG00000154001 ENSG00000105401 ENSG00000169047 ENSG00000134308 ENSG00000101280 ENSG00000091409 ENSG00000167393 ENSG00000167965 ENSG00000176533 ENSG00000171791 ENSG00000187266 ENSG00000100485 ENSG00000124762 ENSG00000065243 ENSG00000156475 ENSG00000172037 ENSG00000177455 ENSG00000145431 ENSG00000103479 ENSG00000053747 ENSG00000041982 ENSG00000228083 ENSG00000233816 ENSG00000120235 ENSG00000136869 ENSG00000186803 ENSG00000147885 ENSG00000108821 ENSG00000120242 ENSG00000214042 ENSG00000170027 ENSG00000108342 ENSG00000081052 ENSG00000068971 ENSG00000197461 ENSG00000139219 ENSG00000170962 ENSG00000118785 ENSG00000112640 ENSG00000092020 ENSG00000140285 ENSG00000127588 ENSG00000154188 ENSG00000124253 ENSG00000069966 ENSG00000113494 ENSG00000168685 ENSG00000188379 ENSG00000171855 ENSG00000073711 ENSG00000153094 ENSG00000221914 ENSG00000181104 ENSG00000115904 ENSG00000196468 ENSG00000164399 ENSG00000184349 ENSG00000137801 ENSG00000142166 ENSG00000049130 ENSG00000145623 ENSG00000128052 ENSG00000143590 ENSG00000123374 ENSG00000037280 ENSG00000104432 ENSG00000162188 ENSG00000167414 ENSG00000118972 ENSG00000132906 ENSG00000127928 ENSG00000112280 ENSG00000142627 ENSG00000005961 ENSG00000099985 ENSG00000111713 ENSG00000169242 ENSG00000234829 ENSG00000078304 ENSG00000128272 ENSG00000081913 ENSG00000102466 ENSG00000135446 ENSG00000113296 ENSG00000156427 ENSG00000134853 ENSG00000040199 ENSG00000155629 ENSG00000049089 ENSG00000186469 ENSG00000104812 ENSG00000112576 ENSG00000134460 ENSG00000137713 ENSG00000070193 ENSG00000157404 ENSG00000243364 ENSG00000110799 ENSG00000130702 ENSG00000167083 ENSG00000108443 ENSG00000141564 ENSG00000174021 ENSG00000102678 ENSG00000012048 ENSG00000100385 ENSG00000213949 ENSG00000136997 ENSG00000066027 ENSG00000175766 ENSG00000105810 ENSG00000077782 ENSG00000292332 ENSG00000182578 ENSG00000114450 ENSG00000112964 ENSG00000147168 ENSG00000078369 ENSG00000189056 ENSG00000064547 ENSG00000091879 ENSG00000132356 ENSG00000105568 ENSG00000070388 ENSG00000019991 ENSG00000002330 ENSG00000105550 ENSG00000138798 ENSG00000198793 ENSG00000118971 ENSG00000242616 ENSG00000064300 ENSG00000101680 ENSG00000169231 ENSG00000099617 ENSG00000137080 ENSG00000149089 ENSG00000136457 ENSG00000105664 ENSG00000029559 ENSG00000206384 ENSG00000213231 ENSG00000186340 ENSG00000113520 ENSG00000160447 ENSG00000236637 ENSG00000171105 ENSG00000172380 ENSG00000134871 ENSG00000164171 ENSG00000147145 ENSG00000160741 ENSG00000066468 ENSG00000074211 ENSG00000160867 ENSG00000078579 ENSG00000162409 ENSG00000184371 ENSG00000135424 ENSG00000123143 ENSG00000115232 ENSG00000114279 ENSG00000175305 PMC5618562__F2 Interplay between G-Protein Coupled Receptors (GPCR) signaling regulated by melatonin and GPCR signaling regulating YAP/TAZ ENSG00000163914 ENSG00000168036 ENSG00000131023 ENSG00000089225 PMC4583820__F1 Involvement of IAP proteins and IAP antagonists in the apoptosis and NFKB pathways [, ] ENSG00000104856 ENSG00000137275 ENSG00000102871 ENSG00000131323 ENSG00000168040 ENSG00000127191 PMC5514949__F7 Negative regulation of tumor-infiltrating NK cell in clear cell renal cell carcinoma patients through the exosomal pathway PMC11685696__F4 Intestinal microbiota mediate CID through the TLR receptor and cGAS-STING pathway ENSG00000183735 ENSG00000226275 ENSG00000239732 ENSG00000164430 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC5618562__F4 Interplay between melatonin signaling, cell contact-cell polarity complexes, mechanotransduction, and YAP/TAZ ENSG00000198929 ENSG00000168036 ENSG00000131023 ENSG00000089225 PMC11685696__F3 Mechanism by which intestinal microbiota regulates intestinal mucosal injury through STING pathways ENSG00000183735 ENSG00000164430 PMC5618562__F3 Interplay between melatonin, YAP/TAZ, and metabolic pathways ENSG00000169047 ENSG00000198793 ENSG00000133124 ENSG00000168036 ENSG00000089225 PMC4791395__F3 Stealth strategies of Brucella ENSG00000105656 ENSG00000136869 PMC4890468__F2 The mammalian target of rapamycin (mTOR) signaling pathway and crosstalk with the mitogen-activated protein kinase (MAPK) pathway and the phosphatidylinositol 3-kinase (PI3K) pathway ENSG00000174307 ENSG00000169047 ENSG00000136997 ENSG00000146648 ENSG00000196712 PMC4791395__F2 Strategies of Brucella to evade the innate and adaptive immunity ENSG00000239732 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC8650121__F1 Antioxidant Activity, Molecular Docking, Quantum Studies and In Vivo Antinociceptive Activity of Sulfonamides Derived From Carvacrol ENSG00000092439 ENSG00000137672 ENSG00000138741 PMC1899380__F1 Late steps in corrin ring biosynthesis in serovar Typhimurium ENSG00000142192 ENSG00000124479 ENSG00000196839 PMC6493983__F1 Pathways to cellular senescence in eukaryotic cells ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC10384366__F1 Natural Products Regulation of Molecular Signaling Pathway in Dermal Papilla Stem Cells ENSG00000168036 ENSG00000128602 PMC8391142__F3 The Hedgehog Pathway in Chemoresistance of Gastrointestinal Cancers ENSG00000141867 ENSG00000138336 ENSG00000288145 ENSG00000198793 ENSG00000134121 ENSG00000168610 PMC3879068__F3 Networks showing metabolic pathways differentially modulated between H and L groups ENSG00000100591 ENSG00000174080 ENSG00000170522 ENSG00000151365 ENSG00000158887 ENSG00000169710 ENSG00000117152 ENSG00000123104 ENSG00000152689 ENSG00000099194 ENSG00000140299 ENSG00000109956 PMC8391142__F2 The Hedgehog Pathway in Chemoresistance of Gastrointestinal Cancers ENSG00000125538 PMC4576950__F2 Processing of the Notch signaling pathway and the nuclear cycle ENSG00000140564 ENSG00000065526 ENSG00000148400 ENSG00000273529 ENSG00000132964 ENSG00000114315 PMC8391142__F1 The Hedgehog Pathway in Chemoresistance of Gastrointestinal Cancers ENSG00000157933 ENSG00000125398 ENSG00000148400 ENSG00000103222 ENSG00000272398 ENSG00000026508 ENSG00000128602 ENSG00000118777 PMC9179862__F9 CXCL12/CXCR4/ACKR3 Signaling Axis Regulates PKM2 and Glycolysis ENSG00000107562 ENSG00000144476 ENSG00000121966 PMC3756614__F11 Signaling pathways used by EGF to stimulate goblet cell proliferation ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC3099575__F5 Model of relationship among Hfe, Tmprss6, and the Bmp/Smad signaling pathway in hepcidin regulation ENSG00000010704 ENSG00000187045 ENSG00000105697 ENSG00000125968 PMC3088084__F4 Therapeutic effects can be monitored using DMR on scant cell populations ENSG00000198793 ENSG00000146648 PMC8915145__F3 Common pathways control autoimmune susceptibility and TFH cell homeostasis ENSG00000163599 ENSG00000198589 PMC6109707__F8 Complement activation and involvement during alcoholic liver disease ENSG00000166278 ENSG00000236625 PMC9658582__F5 Tocotrienol-Rich Fraction and Levodopa Regulate Proteins Involved in Parkinson’s Disease-Associated Pathways in Differentiated Neuroblastoma Cells: Insights from Quantitative Proteomic Analysis ENSG00000156026 ENSG00000015285 ENSG00000127948 PMC3499881__F1 Regulation of the polyamines putrescine, spermidine and spermine by biosynthetic enzymes (shown in green) and catabolic enzymes (shown in red) ENSG00000168003 ENSG00000088826 ENSG00000148832 ENSG00000123505 ENSG00000116649 ENSG00000102172 PMC8749860__F1 BRCA1 and Metastasis: Outcome of Defective DNA Repair ENSG00000149311 ENSG00000012048 ENSG00000083093 ENSG00000051180 ENSG00000139618 PMC6932941__F3 Diagram of the pathways involved in the metabolic interaction of glycolysis, mitochondrial respiration, and hyaluronan synthesis ENSG00000147162 ENSG00000026508 ENSG00000079432 PMC3892099__F8 Summary of parthenolide-induced signaling pathway in NSCLC cell lines ENSG00000128272 ENSG00000144895 ENSG00000120889 PMC8117419__F2 Ferroptosis in Ovarian Cancer: A Novel Therapeutic Strategy ENSG00000167468 PMC11983172__F11 Xuanfei Baidu Decoction Alleviated Sepsis-Induced ALI by Modulating Gut Microbial Homeostasis and Promoting Inflammation Resolution: Bioinformatics and Experimental Study ENSG00000136869 ENSG00000125245 PMC2939232__F10 Acute hyperglycemia rapidly stimulates VEGF mRNA translation in the kidney. Role of angiotensin type 2 receptor (AT2) ENSG00000198793 ENSG00000284161 ENSG00000167658 PMC4033012__F2 Schematic representation of the NALCN channelosome ENSG00000133958 ENSG00000102452 ENSG00000036828 ENSG00000144406 PMC9354910__F3 Common regulatory pathway of COVID-19 and multiple inflammatory diseases and the molecular mechanism of cepharanthine in the treatment of COVID-19 ENSG00000180210 ENSG00000169245 ENSG00000081041 ENSG00000224320 ENSG00000161921 ENSG00000105397 ENSG00000198793 ENSG00000106546 PMC9252571__F1 Metabolic pathways implicated in ferroptosis ENSG00000167468 ENSG00000115107 ENSG00000079999 PMC6766640__F3 Convergence of the TGFB and collateral signaling pathways regulates transcription of the profibrotic PAI-1 and CTGF genes ENSG00000126016 ENSG00000109321 ENSG00000134982 ENSG00000136997 ENSG00000142920 ENSG00000168036 ENSG00000150457 ENSG00000081051 ENSG00000132849 ENSG00000131023 ENSG00000169435 PMC3666170__F3 Role of Cx43 and Panx1 hemichannels in paracrine signaling in taste transduction ENSG00000070985 ENSG00000110218 ENSG00000137841 PMC3046528__F6 Monosodium urate (MSU)-mediated inflammation and the roles of spleen tyrosine kinase (Syk) and Nlrp3 ENSG00000187796 PMC7690394__F1 Folic acid metabolism and 5-MTHF transport across the choroid plexus epithelium in the brain ENSG00000228716 ENSG00000136371 PMC6647482__F3 The interplay between purinergic signaling and ComC activation during sterile brain inflammation ENSG00000163220 ENSG00000189403 PMC9146749__F7 Infectious Bronchitis Virus Nsp14 Degrades JAK1 to Inhibit the JAK-STAT Signaling Pathway in HD11 Cells ENSG00000115415 PMC3351347__F7 Control of Pax3 expression in the caudal neurectoderm via NCE2 ENSG00000135903 ENSG00000168036 ENSG00000164690 ENSG00000074219 PMC6678794__F1 Delta-like ligand 4 (DLL4) and Jagged1 exert different effects on Th subsets differentiation ENSG00000128917 ENSG00000134982 PMC115962__F5 IFNG signaling pathway showing the defects in the human fibroblast mutants B3, B9, and B10 ENSG00000111537 ENSG00000115415 PMC6261508__F1 MTOR pathway in treatment of epilepsy: a clinical update ENSG00000100150 ENSG00000114388 ENSG00000266173 ENSG00000198793 ENSG00000164327 PMC3503525__F1 WNTS AND TGFB IN SYNAPTOGENESIS: OLD FRIENDS SIGNALLING AT NEW PLACES ENSG00000134982 ENSG00000168036 PMC6079151__F4 WNT pathway promoting endometrial carcinogenesis ENSG00000134982 ENSG00000168036 PMC7600741__F3 Ca2+-signaling pathways and HCC cell apoptosis ENSG00000167323 ENSG00000293604 ENSG00000156026 PMC9259665__F2 Trends in insulin resistance: insights into mechanisms and therapeutic strategy ENSG00000131473 ENSG00000168792 ENSG00000150907 ENSG00000124253 PMC2712099__F2 The aryl hydrocarbon receptor (AHR) signalling pathway ENSG00000106546 PMC10984988__F9 Insights from bioinformatics analysis reveal that lipopolysaccharide induces activation of chemokine-related signaling pathways in human nasal epithelial cells ENSG00000023445 ENSG00000104856 ENSG00000148346 ENSG00000288411 ENSG00000144802 ENSG00000108342 ENSG00000134070 ENSG00000184371 ENSG00000115009 PMC8727603__F2 Rotavirus Interactions With Host Intestinal Epithelial Cells ENSG00000169245 ENSG00000213928 ENSG00000088888 ENSG00000115415 ENSG00000157601 ENSG00000164342 PMC5746415__F1 Regulation of PD-1/PD-L1 pathway and resistance to PD-1/PD-L1 blockade ENSG00000089692 ENSG00000108688 ENSG00000168036 ENSG00000169429 ENSG00000273686 ENSG00000049768 PMC9058838__F4 Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway ENSG00000100288 ENSG00000087085 ENSG00000074800 ENSG00000068976 ENSG00000088766 ENSG00000172482 ENSG00000153395 ENSG00000111666 ENSG00000124253 ENSG00000166123 ENSG00000115419 ENSG00000159399 ENSG00000101290 ENSG00000084774 PMC3471948__F4 Cross-Species Genome Wide Expression Analysis during Pluripotent Cell Determination in Mouse and Rat Preimplantation Embryos ENSG00000145604 ENSG00000100906 ENSG00000140795 ENSG00000006451 ENSG00000136997 PMC4285772__F7 SOCS3-mediated regulation of inflammatory cytokines in PTEN and p53 inactivated triple negative breast cancer model ENSG00000173039 ENSG00000168610 PMC3916724__F1 Molybdenum metabolism in higher plant cells ENSG00000182511 ENSG00000158125 PMC4810800__F2 TGFB1/SMAD signaling pathways in hepatic fibrosis ENSG00000170365 PMC12136530__F8 Proposed mechanism by which arginine inhibits tumor growth ENSG00000036473 ENSG00000084774 PMC3594520__F1 TLR3 immunity to infection in mice and humans ENSG00000132109 ENSG00000183735 ENSG00000102871 ENSG00000179387 ENSG00000131323 ENSG00000255690 ENSG00000215301 ENSG00000164342 PMC2752832__F7 Scheme for up-regulation of the PAI-1 gene by EGF in glioblastoma ENSG00000291971 ENSG00000138798 ENSG00000163814 ENSG00000146648 PMC6204952__F4 GC-C activation, intracellular effects ENSG00000111537 ENSG00000125538 ENSG00000001626 PMC5800892__F7 TRAF-STOP Treatment Reduces Atherosclerosis and Preserves ImmunityBinding of CD40L to CD40 results in the recruitment of tumor necrosis factor receptor-associated factors (TRAFs), and propagation of signaling ENSG00000105656 ENSG00000175104 PMC7014934__F1 An overview of autophagy machinery ENSG00000123395 ENSG00000145782 ENSG00000057663 PMC3969300__F1 Establishment of left/right (LR) asymmetry during development ENSG00000152093 ENSG00000156574 ENSG00000114739 PMC9455056__F4 MYCN and Metabolic Reprogramming in Neuroblastoma ENSG00000128050 ENSG00000102967 ENSG00000084774 ENSG00000254550 PMC4801062__F3 ZBIT Bioinformatics Toolbox: A Web-Platform for Systems Biology and Expression Data Analysis ENSG00000138798 ENSG00000258429 ENSG00000197461 PMC9455056__F3 MYCN and Metabolic Reprogramming in Neuroblastoma ENSG00000065911 ENSG00000100714 ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC9655262__F4 Necroptosis: A Pathogenic Negotiator in Human Diseases ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC11024365__F9 Proposed modeling of antioxidant mechanisms in H ENSG00000105227 ENSG00000084774 PMC8658611__F5 Impact of Cigarette Smoking on the Expression of Oxidative Stress-Related Genes in Cumulus Cells Retrieved from Healthy Women Undergoing IVF ENSG00000167996 ENSG00000117707 ENSG00000176153 ENSG00000135624 ENSG00000101557 ENSG00000079999 PMC9455056__F1 MYCN and Metabolic Reprogramming in Neuroblastoma ENSG00000092621 ENSG00000159399 PMC9124882__F2 Recent advances in cancer immunotherapy: Modulation of tumor microenvironment by Toll-like receptor ligands ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC6881706__F1 Circular RNAs Regulate Cancer Onset and Progression via Wnt/Beta-Catenin Signaling Pathway ENSG00000134982 ENSG00000115266 ENSG00000168036 PMC6348061__F2 Simplified diagram of the acetylcholine (ACh)-signaling pathway in human lung cells ENSG00000114200 ENSG00000087085 PMC6540157__F1 RNA granules and caprin-1-associated tumorigenesis ENSG00000144895 ENSG00000135387 ENSG00000136997 ENSG00000172795 ENSG00000123908 PMC6287147__F8 Schematic illustration of a working model for the TGFB1/SMAD/Snail pathway in modulation of EMT-dependent fibrosis in SGEC PMC10380572__F2 Fc Epsilon RI–Neuroimmune Interplay in Pruritus Triggered by Particulate Matter in Atopic Dermatitis Patients ENSG00000213658 ENSG00000010671 PMC7729937__F11 Proposed mechanism of the differential actions of arecoline on cell growth among RWPE-1 (A), PC-3 (B), and LNCaP (C) cells ENSG00000112576 ENSG00000134057 ENSG00000135446 PMC8117014__F4 Research Progress of circRNAs in Head and Neck Cancers ENSG00000150938 ENSG00000164379 ENSG00000138798 ENSG00000120868 ENSG00000146648 PMC3961947__F1 Molecular pathways altered by green tea extract ENSG00000171791 PMC6065049__F6 PKC pathway for prolactin regulation of the metabolic genes for citrate-producing prostate cells ENSG00000177606 PMC4689760__F1 Cholesterol biosynthesis pathway is altered in CEM/R2 cells ENSG00000057252 ENSG00000112972 ENSG00000172893 ENSG00000107798 ENSG00000197429 ENSG00000113161 ENSG00000052802 ENSG00000167780 ENSG00000067064 ENSG00000132196 ENSG00000001630 ENSG00000116133 ENSG00000109929 ENSG00000149809 ENSG00000104549 PMC6435069__F2 Complement regulators ENSG00000113600 ENSG00000117335 ENSG00000244731 ENSG00000166278 ENSG00000062485 ENSG00000236625 PMC6435069__F1 Complement pathways ENSG00000244731 ENSG00000166278 ENSG00000062485 ENSG00000236625 PMC6609813__F2 Suppressive mechanism of regulatory T (Treg) cells ENSG00000089692 ENSG00000134982 ENSG00000049768 ENSG00000026103 PMC7993742__F3 Protein-protein interaction (PPI) of differentially expressed aging-related genes ENSG00000178999 ENSG00000072274 ENSG00000091409 ENSG00000120885 ENSG00000136942 ENSG00000064666 ENSG00000138778 ENSG00000063177 ENSG00000136997 ENSG00000169429 ENSG00000135919 ENSG00000280548 ENSG00000151882 ENSG00000262406 ENSG00000123975 ENSG00000173156 ENSG00000101224 ENSG00000166816 ENSG00000117399 ENSG00000117724 ENSG00000133048 ENSG00000133110 ENSG00000161921 ENSG00000118785 ENSG00000132646 ENSG00000163584 ENSG00000175899 ENSG00000134070 ENSG00000127824 ENSG00000143196 ENSG00000135218 ENSG00000181163 ENSG00000106397 ENSG00000120149 ENSG00000137563 ENSG00000145386 ENSG00000112715 ENSG00000118971 ENSG00000166851 ENSG00000157557 ENSG00000115828 ENSG00000186340 ENSG00000149968 ENSG00000197958 ENSG00000181374 ENSG00000122565 ENSG00000148346 ENSG00000150594 ENSG00000081041 ENSG00000137673 ENSG00000101057 ENSG00000169860 ENSG00000273686 ENSG00000164171 ENSG00000291973 ENSG00000125743 ENSG00000140416 ENSG00000066468 ENSG00000160867 ENSG00000163131 ENSG00000291748 ENSG00000145649 ENSG00000092841 PMC9569594__F10 Novel Thieno [2,3-b]pyridine Anticancer Compound Lowers Cancer Stem Cell Fraction Inducing Shift of Lipid to Glucose Metabolism ENSG00000069482 ENSG00000135454 PMC4219530__F1 Transcriptome analysis of human adipocytes implicates the NOD-like receptor pathway in obesity-induced adipose inflammation ENSG00000023445 ENSG00000162711 ENSG00000104365 ENSG00000167207 ENSG00000187796 ENSG00000163739 ENSG00000269335 ENSG00000132357 ENSG00000091106 ENSG00000213341 ENSG00000106100 ENSG00000108691 ENSG00000140368 ENSG00000103490 ENSG00000125538 ENSG00000169900 ENSG00000175104 ENSG00000064012 PMC4250958__F1 Differential Apoptosis in Mucosal and Dermal Wound Healing ENSG00000132906 ENSG00000102871 ENSG00000138794 ENSG00000064012 ENSG00000164305 PMC4086428__F4 Predicted network linking pancreatic cancer miRNA markers, known pancreatic cancer genetic lesions, and DAMPs ENSG00000012048 ENSG00000169554 ENSG00000189403 ENSG00000171791 ENSG00000139618 PMC4086428__F3 Three commonly differentially expression MicroRNAs in pancreatic cancer tissue and patient blood: MicroRNAs 21, 155, and 200 ENSG00000169554 ENSG00000157764 ENSG00000164938 ENSG00000172936 PMC11652788__F5 TsRNA in neurodegenerative diseases ENSG00000037474 ENSG00000172409 PMC6723754__F3 Signaling pathways elicited by stabilin-mediated phagocytosis of apoptotic cells ENSG00000144366 PMC7669705__F2 Opportunities for combination therapy ENSG00000134057 ENSG00000135446 ENSG00000198793 ENSG00000087586 ENSG00000166851 ENSG00000139687 ENSG00000196712 PMC8038661__F2 Extracellular regulators of adipogenesis ENSG00000154342 ENSG00000170365 ENSG00000106571 ENSG00000148400 ENSG00000198793 ENSG00000145321 ENSG00000168036 ENSG00000107485 ENSG00000164690 ENSG00000179348 PMC7599682__F2 SRC structure and regulation ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC10533267__F7 sNASP Mutation Aggravates to the TLR4-Mediated Inflammation in SLE by TAK1 Pathway ENSG00000183735 ENSG00000131323 ENSG00000175104 PMC4835424__F1 Plausible biosynthetic pathway leading to atisine in A ENSG00000110921 ENSG00000197429 ENSG00000184207 PMC5139139__F4 Linking identical processes found between two metabolic maps ENSG00000159128 ENSG00000111537 ENSG00000125347 ENSG00000105669 PMC5739856__F1 Neutrophils promote tumour growth through direct and indirect mechanisms ENSG00000102970 ENSG00000118520 PMC2924908__F2 Complement - a key system for immune surveillance and homeostasis ENSG00000134982 ENSG00000132693 PMC10474740__F2 Angiogenesis modulated by CD93 and its natural ligands IGFBP7 and MMRN2: a new target to facilitate solid tumor therapy by vasculature normalization ENSG00000173269 ENSG00000291971 ENSG00000113070 ENSG00000150907 ENSG00000169047 ENSG00000163453 ENSG00000125810 ENSG00000140443 PMC2729336__F3 Transcriptional control of HC and amacrine cell development ENSG00000138083 ENSG00000143032 ENSG00000117707 ENSG00000168267 ENSG00000016082 PMC10474740__F3 Angiogenesis modulated by CD93 and its natural ligands IGFBP7 and MMRN2: a new target to facilitate solid tumor therapy by vasculature normalization ENSG00000070831 ENSG00000173269 ENSG00000291971 ENSG00000163453 ENSG00000125810 ENSG00000108774 PMC10452661__F2 Crosstalk between IL-6 signaling and the PI3K/AKT/mTOR pathway in EAOC ENSG00000117713 ENSG00000198793 PMC10452661__F1 PI3K/AKT/mTOR pathway-related gene alterations involved in the pathogenesis of Endometriosis and Endometriosis-Associated Ovarian Cancer ENSG00000117713 ENSG00000121879 PMC11947373__F1 COVID-19-induced molecular mechanisms that propel OSCC development and chemoresistance ENSG00000162711 ENSG00000130234 ENSG00000198793 PMC5096733__F1 Simplified diagram of mTORC1 and ERK1/2 signaling following muscle contraction ENSG00000284161 ENSG00000167658 PMC8046170__F3 Human complement cascades ENSG00000039537 ENSG00000113600 ENSG00000013441 ENSG00000244731 ENSG00000166278 ENSG00000132693 ENSG00000182326 ENSG00000236625 PMC7882174__F2 Role of leonurine in cardiovascular disease ENSG00000002330 ENSG00000198793 PMC7779461__F5 Chemokine Signaling Pathway Based on DAVID Analysis of KEGG Pathway Database ENSG00000002330 PMC8351522__F2 Biomarkers and targets of mitochondrial dynamics ENSG00000094631 ENSG00000215021 ENSG00000110497 ENSG00000183735 ENSG00000203485 ENSG00000175193 ENSG00000162600 ENSG00000134982 ENSG00000158828 ENSG00000086758 ENSG00000247077 PMC8351522__F5 Biomarkers and targets of mitochondrial dynamics ENSG00000162711 ENSG00000111537 ENSG00000163568 PMC8351522__F4 Biomarkers and targets of mitochondrial dynamics ENSG00000101574 ENSG00000171759 ENSG00000108561 PMC10865418__F5 Schematic diagram illustrating the hypothesis of signaling regulation in aGVHD ENSG00000198793 ENSG00000049768 PMC8351522__F1 Biomarkers and targets of mitochondrial dynamics ENSG00000094631 ENSG00000203485 ENSG00000168958 ENSG00000175193 ENSG00000162600 ENSG00000134278 ENSG00000134982 ENSG00000163568 ENSG00000116688 ENSG00000158828 ENSG00000086758 ENSG00000171109 PMC3136902__F1 IL-1RI signaling ENSG00000125538 ENSG00000177606 ENSG00000134070 ENSG00000172936 ENSG00000185187 ENSG00000175104 ENSG00000184216 PMC3531074__F3 Network exploration options ENSG00000183878 PMC6290135__F1 Polyamine biosynthetic pathway in single-celled parasitic eukaryotes ENSG00000112977 ENSG00000042832 ENSG00000288145 ENSG00000129932 PMC7254625__F1 Pathogenesis of non-hereditary brain arteriovenous malformation and therapeutic implications ENSG00000196411 ENSG00000157764 ENSG00000198793 PMC8928114__F4 Immunology of Inflammatory Bowel Disease: Molecular Mechanisms and Therapeutics ENSG00000162594 ENSG00000105397 ENSG00000102871 ENSG00000103522 ENSG00000105639 ENSG00000127191 ENSG00000168610 ENSG00000168685 PMC3355968__F2 Regulation of Mcl-1 and Snail by AKT, ERK, and IKK signaling pathway ENSG00000127445 PMC3355968__F1 Regulation of FOXO3 and Beta-catenin by AKT, ERK, and IKK signaling pathway ENSG00000145604 ENSG00000168036 PMC6433688__F11 Illustration of the FGF16 signalling pathway to regulate Leydig cell development ENSG00000196468 PMC2822851__F1 Signal transduction pathway from integrin receptors to actin cytoskeleton ENSG00000145362 ENSG00000157404 ENSG00000147202 ENSG00000128512 ENSG00000070831 ENSG00000143878 ENSG00000291971 ENSG00000134215 ENSG00000106299 ENSG00000171475 ENSG00000099942 ENSG00000092820 ENSG00000141968 ENSG00000112290 ENSG00000156299 ENSG00000169750 ENSG00000010810 ENSG00000163914 ENSG00000015285 ENSG00000088538 ENSG00000163554 ENSG00000163017 ENSG00000160293 ENSG00000198947 PMC8693951__F1 TLR7 signaling in lupus B cells ENSG00000239732 ENSG00000111537 ENSG00000120280 ENSG00000115415 ENSG00000139370 ENSG00000186716 ENSG00000153064 ENSG00000172936 ENSG00000110057 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC4792934__F10 Proposed store-operated signaling mechanisms in end-feet of Müller glia ENSG00000196531 ENSG00000144935 ENSG00000167323 PMC3857640__F5 Conditioned media from mouse osteosarcoma cells promote MC3T3-E1 cell proliferation using JAKs and PI3-K/Akt signal crosstalk ENSG00000105639 ENSG00000168610 PMC6479272__F13 Partly hypothetical model describing the characteristic shifts of balance within the sphingomyelin/salvage pathway attributed to immune low and immune high tumor subtypes/subgroups of patients ENSG00000177575 ENSG00000129226 ENSG00000064547 ENSG00000171517 ENSG00000285281 ENSG00000135587 ENSG00000143418 ENSG00000139624 ENSG00000100422 ENSG00000138744 ENSG00000198964 ENSG00000063176 ENSG00000223802 ENSG00000172292 ENSG00000136960 ENSG00000154227 ENSG00000170458 ENSG00000164023 ENSG00000198670 ENSG00000170989 ENSG00000163082 PMC6880815__F3 Putative biosynthetic pathway to the nanangenines ENSG00000126218 ENSG00000088926 PMC9578081__F5 11-Oxygenated C19 steroids are the predominant androgens responsible for hyperandrogenemia in Cushing’s disease ENSG00000203859 ENSG00000179142 ENSG00000176387 PMC7339600__F5 Protein-protein interaction network for the DEGs in the brown, blue and red modules ENSG00000130957 ENSG00000157404 ENSG00000169562 ENSG00000159461 ENSG00000115718 ENSG00000137766 ENSG00000087303 ENSG00000131730 ENSG00000128052 ENSG00000101438 ENSG00000181374 ENSG00000214872 ENSG00000125810 ENSG00000152128 ENSG00000101162 ENSG00000175984 ENSG00000177504 ENSG00000142661 ENSG00000146409 ENSG00000105369 ENSG00000197893 ENSG00000120915 ENSG00000079257 ENSG00000033800 ENSG00000076706 ENSG00000101306 ENSG00000140465 ENSG00000172508 ENSG00000145949 ENSG00000164708 ENSG00000146648 ENSG00000156535 ENSG00000143882 ENSG00000152556 PMC4314775__F7 Proposed mechanism of differential regulations of NFKB – miR-29b – p53 pathway by S100A7 in different types of breast cancer cells ENSG00000100811 ENSG00000070831 ENSG00000143556 PMC5056381__F8 The anti-hyperglycemic efficacy of a lipid-lowering drug Daming capsule and the underlying signaling mechanisms in a rat model of diabetes mellitus ENSG00000159224 ENSG00000168036 PMC7339600__F6 miRNA-TF-target regulatory network ENSG00000131730 ENSG00000157404 ENSG00000134871 ENSG00000112715 ENSG00000140465 PMC6412338__F3 mTOR signaling network ENSG00000177169 ENSG00000117525 ENSG00000150907 ENSG00000284161 ENSG00000118515 ENSG00000155792 PMC10916191__F8 Working model of lipid synthesis induces by PPAR and cell cycle regulation in GCs after MLN4924 treatment ENSG00000135218 ENSG00000135446 ENSG00000132646 ENSG00000169710 ENSG00000105810 ENSG00000171791 PMC5308742__F8 De-novo NAD+ synthesis regulates SIRT1-FOXO1 apoptotic pathway in response to NQO1 substrates in lung cancer cells ENSG00000105835 ENSG00000150907 ENSG00000096717 PMC6883191__F2 Evaluation of the immunobiological effects of a regenerative far-infrared heating system in pigs ENSG00000111537 ENSG00000154589 ENSG00000170458 ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC3843070__F5 Model illustrating the potential role of CRKL in recruiting NleH1 to inhibit RPS3/NFKB signaling during A/E pathogen infection ENSG00000149273 ENSG00000099942 PMC10898168__S1 Inhalable hybrid nanovaccines (NVRBD-MLipo) with virus-biomimetic structure against SARS-CoV-2 infection ENSG00000136869 PMC11554530__F2 Functional plasticity of Tregs and Th17 cells ENSG00000181847 ENSG00000049768 ENSG00000168610 PMC6685593__F10 Piezo1 promotes tumorigenesis of prostate cancer ENSG00000135446 ENSG00000198793 ENSG00000103335 PMC8146082__F2 Unfolded Protein Response: An Overview ENSG00000128272 ENSG00000144895 ENSG00000162772 PMC3023029__F2 Intracellular transport pathway of Shiga toxin ENSG00000013016 ENSG00000120805 ENSG00000070831 ENSG00000172780 ENSG00000205302 ENSG00000107863 ENSG00000028528 ENSG00000172007 ENSG00000106266 ENSG00000151532 PMC7586431__F5 Statin therapy for cancer ENSG00000198793 ENSG00000164305 PMC7586431__F3 Statin therapy for coronary heart disease ENSG00000123374 ENSG00000076003 ENSG00000166508 PMC6966530__F11 Effect of tyrosine phosphorylation of PDHK1 and PKM2 on the fates of pyruvate and acetyl-CoA in normal and cancer cells (modified according to ) ENSG00000131473 ENSG00000169710 PMC3742712__F2 Inflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000091106 PMC6332483__F6 Schematic model of SNHG6 in CRC cells PMC5907676__F1 Wnt signaling pathway ENSG00000124102 ENSG00000156076 ENSG00000134982 ENSG00000168036 PMC6269119__F1 The activation of an intracellular channel promotes the trafficking and secretion of a cytokine ENSG00000108691 ENSG00000136869 PMC8263212__F1 Mechanisms Underlying the Role of Myeloid-Derived Suppressor Cells in Clinical Diseases: Good or Bad ENSG00000115415 ENSG00000134982 ENSG00000118520 ENSG00000168610 PMC3109490__F1 Francisella tularensis tularensis targets the PI3K/Akt pathway at multiple levels PMC11524448__F8 T3SS triggered LTB4 synthesis differs between neutrophils and macrophages ENSG00000162711 ENSG00000167323 PMC6963649__F2 Simplified schematic diagram showing synergistic and antagonistic interactions between the ABA signaling pathway and other hormonal signaling pathways during abiotic and biotic stress ENSG00000105722 ENSG00000136997 PMC3766375__F2 Fat side of Prostate Cancer ENSG00000131473 ENSG00000065833 ENSG00000172005 ENSG00000113161 ENSG00000169710 PMC2742086__F2 Functional and structural organization of migratory mesenchymal cells ENSG00000070831 ENSG00000134982 ENSG00000133961 PMC8946764__F2 Unravelling the Role of Kinases That Underpin Androgen Signalling in Prostate Cancer ENSG00000110721 ENSG00000159322 ENSG00000064393 ENSG00000198648 ENSG00000060237 ENSG00000110931 ENSG00000065559 ENSG00000137764 ENSG00000168610 ENSG00000165238 ENSG00000136807 ENSG00000153721 ENSG00000135446 ENSG00000162545 ENSG00000105810 ENSG00000132964 ENSG00000068120 ENSG00000146648 ENSG00000159399 ENSG00000135250 PMC5907676__F3 Cross-talk between Wnt and signaling pathways ENSG00000198793 ENSG00000168036 ENSG00000196470 PMC3543749__F2 Telomere maintenance pathway ENSG00000166340 ENSG00000145912 ENSG00000291996 ENSG00000164362 ENSG00000128513 PMC3543749__F1 Insulin/IGF-1 signaling pathway ENSG00000171105 ENSG00000153094 ENSG00000169047 ENSG00000142082 ENSG00000118971 ENSG00000283100 ENSG00000145604 ENSG00000103479 ENSG00000117020 ENSG00000138764 ENSG00000081913 ENSG00000101049 ENSG00000150907 ENSG00000133124 ENSG00000118515 ENSG00000040199 ENSG00000096717 PMC3766375__F3 Fat side of Prostate Cancer ENSG00000131473 ENSG00000198793 ENSG00000136997 ENSG00000172005 ENSG00000113161 ENSG00000169710 PMC3408141__F8 The molecular pathway required for NOD2-dependent autophagy ENSG00000177169 ENSG00000167207 ENSG00000105568 PMC2615558__F4 Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus ENSG00000132906 ENSG00000100234 ENSG00000108342 ENSG00000162772 ENSG00000166147 ENSG00000104368 ENSG00000281766 ENSG00000011422 ENSG00000066336 ENSG00000116132 ENSG00000064012 ENSG00000080839 ENSG00000026103 PMC8467246__F1 Landscape of IFN/ISG Signaling in HIV-1-Infected Macrophages and Its Possible Role in the HIV-1 Latency ENSG00000184979 ENSG00000145388 ENSG00000169245 ENSG00000187608 ENSG00000183486 ENSG00000198492 ENSG00000157601 ENSG00000239713 ENSG00000091542 ENSG00000125347 ENSG00000165819 ENSG00000172183 PMC7037436__F8 Andrographolide biosynthetic gene activation by MJ elicitation in Andrographis paniculata ENSG00000110921 ENSG00000197429 ENSG00000151151 PMC7226813__F4 JNK enhances fibrosis via crosstalk with TGFB, PDGF, STAT3, and WNT signaling pathways ENSG00000177606 ENSG00000168036 ENSG00000168610 PMC7226813__F3 JNK modulates keratinocyte production of inflammatory cytokine/chemokines and recruitment of immune cells in psoriasis ENSG00000111537 ENSG00000115009 PMC7226813__F2 JNK regulation of cell cycle progression, cell adhesion, and cell apoptosis ENSG00000002330 ENSG00000102871 ENSG00000177606 ENSG00000100985 ENSG00000127191 PMC7226813__F5 Differential roles of JNK1 and JNK2 in skin cancers ENSG00000177606 ENSG00000083799 ENSG00000164690 PMC4973244__F8 Soluble egg antigens of Schistosoma japonicum induce senescence in activated hepatic stellate cells by activation of the STAT3/p53/p21 pathway ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC6203147__F10 Activation of EGFR/PI3K/Akt signaling pathway ENSG00000144749 PMC8338901__F2 Contributions of EV cargoes in inflammation in CVD ENSG00000135218 ENSG00000198793 ENSG00000172936 ENSG00000162692 ENSG00000175104 ENSG00000184216 ENSG00000026103 PMC5745765__F8 Design of disease network based on mRNA expression analysis and effects of cytokines, chemokines and growth factors described in the literature ENSG00000019991 ENSG00000111537 ENSG00000105329 ENSG00000137033 ENSG00000158477 ENSG00000145777 PMC5943524__F8 Tumor suppressor p53 links ceramide metabolism to DNA damage response through alkaline ceramidase 2 ENSG00000063176 PMC5745765__F7 Design of disease network based on mRNA expression analysis and effects of cytokines, chemokines and growth factors described in the literature ENSG00000019991 ENSG00000111537 ENSG00000105329 ENSG00000137033 ENSG00000158477 ENSG00000145777 PMC5745765__F6 Design of disease network based on mRNA expression analysis and effects of cytokines, chemokines and growth factors described in the literature ENSG00000019991 ENSG00000111537 ENSG00000105329 ENSG00000137033 ENSG00000158477 ENSG00000145777 PMC3321383__F2 Linking Lipids to Alzheimer’s Disease: Cholesterol and Beyond ENSG00000142192 PMC5745765__F5 Design of disease network based on mRNA expression analysis and effects of cytokines, chemokines and growth factors described in the literature ENSG00000019991 ENSG00000111537 ENSG00000105329 ENSG00000137033 ENSG00000158477 ENSG00000145777 PMC5745765__F4 Design of disease network based on mRNA expression analysis and effects of cytokines, chemokines and growth factors described in the literature ENSG00000019991 ENSG00000111537 ENSG00000105329 ENSG00000137033 ENSG00000158477 ENSG00000145777 PMC209479__F2 Inhibitory effects of SOCS-3 and SHP-1 on LIF-mediated gene expression ENSG00000128342 ENSG00000168610 PMC5369969__F14 HDAC inhibitor AR42 interacts with pazopanib to kill trametinib/dabrafenib-resistant melanoma cells in vitro and in vivo ENSG00000094631 ENSG00000149311 ENSG00000177169 ENSG00000002330 ENSG00000198793 ENSG00000196591 ENSG00000100429 ENSG00000163517 ENSG00000108840 PMC209479__F1 Corticotroph SOCS-3 as an intracellular suppressor of cytokine signaling ENSG00000115138 ENSG00000171759 ENSG00000128342 ENSG00000168610 PMC7760347__F2 Mechanisms governing bile acid (BA) enterohepatic circulation ENSG00000160867 ENSG00000131096 ENSG00000179921 PMC8285010__F1 Transcriptomic Changes and the Roles of Cannabinoid Receptors and PPARG in Developmental Toxicities Following Exposure to Δ9-Tetrahydrocannabinol and Cannabidiol ENSG00000065833 ENSG00000150991 ENSG00000167910 ENSG00000180432 ENSG00000100979 ENSG00000165269 ENSG00000173391 PMC8285010__F2 Transcriptomic Changes and the Roles of Cannabinoid Receptors and PPARG in Developmental Toxicities Following Exposure to Δ9-Tetrahydrocannabinol and Cannabidiol ENSG00000121207 ENSG00000284807 ENSG00000187048 ENSG00000197713 ENSG00000292155 ENSG00000140465 PMC5777317__F1 Regulation of the immune response by the aryl hydrocarbon receptor ENSG00000110711 ENSG00000106546 PMC8427239__F1 MicroRNA-9 as a paradoxical but critical regulator of cancer metastasis: Implications in personalized medicine ENSG00000186160 ENSG00000150907 ENSG00000136997 ENSG00000133121 PMC8427239__F3 MicroRNA-9 as a paradoxical but critical regulator of cancer metastasis: Implications in personalized medicine ENSG00000100811 ENSG00000281766 ENSG00000112715 PMC5745765__F9 Design of disease network based on mRNA expression analysis and effects of cytokines, chemokines and growth factors described in the literature ENSG00000019991 ENSG00000111537 ENSG00000105329 ENSG00000137033 ENSG00000158477 ENSG00000145777 PMC9399743__F1 Another level of complex-ity: The role of metabolic channeling and metabolons in plant terpenoid metabolism ENSG00000157554 ENSG00000144410 ENSG00000197429 ENSG00000128602 PMC8188681__F2 Review of the biological and clinical implications of RAS-MAPK pathway alterations in neuroblastoma ENSG00000002330 ENSG00000135446 ENSG00000136997 ENSG00000105810 PMC4065011__F5 Ablation of Coactivator Med1 Switches the Cell Fate of Dental Epithelia to That Generating Hair ENSG00000175264 ENSG00000154342 ENSG00000186395 ENSG00000143546 ENSG00000110799 ENSG00000167768 ENSG00000163220 ENSG00000288335 ENSG00000101280 ENSG00000129514 ENSG00000165816 ENSG00000285348 ENSG00000167772 ENSG00000125398 ENSG00000115457 ENSG00000132205 ENSG00000177606 ENSG00000166482 ENSG00000026508 ENSG00000164690 ENSG00000119912 ENSG00000171819 ENSG00000186832 ENSG00000188783 PMC9941074__F2 Regulating the microenvironment with nanomaterials: Potential strategies to ameliorate COVID-19 ENSG00000162711 ENSG00000213928 ENSG00000276561 ENSG00000142224 ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000130234 ENSG00000184012 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC8188681__F1 Review of the biological and clinical implications of RAS-MAPK pathway alterations in neuroblastoma ENSG00000115904 ENSG00000077782 ENSG00000146648 PMC4973584__F1 Lmx1b and miR135a2 in modulating the Wnt pathway and influencing midbrain size, mDA progenitor specification and neurogenesis ENSG00000134982 ENSG00000125084 PMC7431397__F2 GPCR-mediated proinflammatory signaling via signalosomes and endosomes ENSG00000083799 PMC3060239__F5 Model of the RBP-ROH/STRA6/JAK/STAT pathway PMC8341163__F3 Cas-induced nick processing and strand replacement ENSG00000143799 ENSG00000105486 ENSG00000138346 ENSG00000132646 PMC6701981__F1 Muscle Wasting Diseases: Novel Targets and Treatments ENSG00000112964 ENSG00000169047 ENSG00000112561 ENSG00000168610 ENSG00000105552 ENSG00000163884 ENSG00000140443 PMC8341163__F4 CBE outcomes in gDNA ENSG00000105486 ENSG00000122966 ENSG00000132646 ENSG00000130997 ENSG00000177084 ENSG00000122008 PMC9397555__F2 Involvement of phosphatidylserine receptors in the skeletal muscle regeneration: therapeutic implications ENSG00000167601 ENSG00000135218 ENSG00000291971 ENSG00000140545 PMC11008420__F1 MicroRNAs: A novel signature in the metastasis of esophageal squamous cell carcinoma ENSG00000019991 ENSG00000169554 ENSG00000138798 ENSG00000170558 ENSG00000198793 ENSG00000146648 PMC11008420__F2 MicroRNAs: A novel signature in the metastasis of esophageal squamous cell carcinoma ENSG00000169554 ENSG00000134982 ENSG00000170558 ENSG00000026508 ENSG00000168036 ENSG00000168610 PMC5665169__F3 RNA editing-dependent epitranscriptome diversity in cancer stem cells ENSG00000070756 ENSG00000030419 ENSG00000153944 ENSG00000078399 ENSG00000136997 ENSG00000140391 ENSG00000133961 PMC7407942__F1 Schematic process of the autophagic pathway ENSG00000280616 ENSG00000177169 ENSG00000152348 ENSG00000198382 ENSG00000149212 ENSG00000083290 ENSG00000126775 ENSG00000104142 ENSG00000112561 ENSG00000145782 ENSG00000146648 ENSG00000057663 PMC4754448__F1 Actin associated proteins regulate YAP activity ENSG00000126016 ENSG00000186575 ENSG00000163914 ENSG00000197905 ENSG00000168036 ENSG00000198670 ENSG00000007866 ENSG00000150457 ENSG00000132849 ENSG00000131023 ENSG00000074219 PMC4716054__F1 TrkB-mediated signaling pathways and possible therapeutic targets in cancer ENSG00000002330 ENSG00000198793 PMC7072634__F1 Ultra-structures, components, and functions of intermitochondrial cement (IMC) and mitochondria-associated ER membranes (MAMs) in male germ cells are summarized ENSG00000170627 ENSG00000095627 ENSG00000143194 ENSG00000180113 ENSG00000114127 ENSG00000073146 PMC3507180__F2 Hypothetic regulation of gene expression by HNF-4A by spherical cell shape in FLC-4 cells ENSG00000172955 ENSG00000136997 ENSG00000196498 ENSG00000023839 ENSG00000123610 ENSG00000026103 ENSG00000150630 PMC2746202__F1 Pathway from PI3K to TOR PMC5773178__F2 Signalling pathway impact analysis of gene expression data from H226 MM cells expressing C91A-mutant (mt BAP1) or wild-type BAP1 (wt BAP1) ENSG00000149311 ENSG00000182511 ENSG00000002330 ENSG00000102871 ENSG00000172936 ENSG00000168040 ENSG00000127191 PMC7405480__F3 The PI3K/AKT pathway by binding and ubiquitylation of tumor-regulating proteins in gastric cancer ENSG00000081913 ENSG00000198742 ENSG00000136848 ENSG00000123124 PMC7405480__F2 The p53 signaling pathway by binding and ubiquitylation of tumor-regulating proteins in GC ENSG00000213186 ENSG00000133606 PMC9669386__F1 Ferroptosis in lymphoma: Emerging mechanisms and a novel therapeutic approach ENSG00000168003 ENSG00000128272 ENSG00000151012 ENSG00000115415 ENSG00000167468 ENSG00000111684 ENSG00000099194 ENSG00000115107 ENSG00000123983 PMC7405480__F1 Important signaling pathways by E3 ubiquitin ligases in gastric cancer ENSG00000137075 ENSG00000104517 ENSG00000168036 ENSG00000108375 ENSG00000138942 ENSG00000127191 ENSG00000168610 ENSG00000109670 PMC9121204__F1 Myocardial ischemia/reperfusion injury: Mechanisms of injury and implications for management (Review) ENSG00000196531 ENSG00000102871 ENSG00000198793 ENSG00000168040 ENSG00000168404 ENSG00000168610 ENSG00000285379 PMC6721579__F4 Role of heat shock protein 27 (HSP27) in different cellular apoptotic processes ENSG00000168040 PMC9548139__F1 Sex steroid hormones and risk of breast cancer: a two-sample Mendelian randomization study ENSG00000149084 ENSG00000179142 PMC11747284__F4 Schematic represents the PRLR signaling pathways, including both long and short isoforms ENSG00000010810 ENSG00000169047 ENSG00000113494 PMC6133069__F8 Schematic depiction of the results and proposed hypothesis ENSG00000010810 ENSG00000112992 PMC8657749__F1 Phytosterols in Seaweeds: An Overview on Biosynthesis to Biomedical Applications ENSG00000172680 ENSG00000197429 PMC7751007__F3 Notch signaling pathway ENSG00000122882 ENSG00000112576 ENSG00000283780 ENSG00000138798 ENSG00000114315 PMC5019383__F3 DenHunt - A Comprehensive Database of the Intricate Network of Dengue-Human Interactions ENSG00000104856 ENSG00000242689 ENSG00000113595 ENSG00000102871 ENSG00000138798 ENSG00000150455 ENSG00000142224 ENSG00000095585 ENSG00000149311 ENSG00000226275 ENSG00000213658 ENSG00000184995 ENSG00000170458 ENSG00000186716 ENSG00000136869 ENSG00000175104 PMC10374640__F5 Pharmacological mechanism of Beta-elemene in the treatment of esophageal cancer revealed by network pharmacology and experimental verification ENSG00000132906 ENSG00000109320 ENSG00000198793 ENSG00000170558 ENSG00000168036 ENSG00000171791 ENSG00000112715 ENSG00000073756 ENSG00000168610 ENSG00000124762 ENSG00000183765 ENSG00000089685 ENSG00000132646 ENSG00000116990 ENSG00000100985 ENSG00000139687 ENSG00000146648 PMC8583837__F3 Long Non-Coding RNAs in Endometriosis ENSG00000087245 ENSG00000100985 PMC3436227__F2 MyD-88 dependent TLR signaling pathway ENSG00000174125 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC8900001__F2 Glycolysis in the progression of pancreatic cancer ENSG00000164949 PMC4422156__F1 Schematic of TLR signaling and gene expression following stroke ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC8900001__F1 Glycolysis in the progression of pancreatic cancer ENSG00000140740 ENSG00000147854 ENSG00000164949 PMC3358876__F1 H. pylori-induced miR-155 expression in macrophage immune cells ENSG00000174125 ENSG00000134324 ENSG00000172936 ENSG00000136869 ENSG00000108219 PMC6372777__F2 Figure describes the different effects of gut and brain serotonin on the osteoblast ENSG00000128272 ENSG00000134982 ENSG00000129167 ENSG00000168036 ENSG00000118971 PMC4422156__F2 Poly-IC postconditioning activates the TLR3/IRF3 signaling pathway and increases the IFNB levels and subsequently downregulates TLR/NFKB signaling to decrease the levels of pro-inflammatory cytokines ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC5624635__F1 MicroRNA-16 feedback loop with p53 and Wip1 can regulate cell fate determination between apoptosis and senescence in DNA damage response ENSG00000149311 ENSG00000175054 PMC4904898__F2 PI3K/AKT pathway ENSG00000198793 ENSG00000164327 PMC6000073__F1 LKB1及其下游相关靶点信号通路示意结构图Schematic illustration of LKB1 signaling pathway and related downstream targets for cancer therapy ENSG00000198793 PMC3250525__F3 Visualization of the quantity of genes differentially regulated by Gamma-tocotrienol (GT3) and Alpha-tocopherol (aTOC) using the KEGG cell cycle pathway ENSG00000145604 ENSG00000180210 ENSG00000182628 ENSG00000094804 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000205250 ENSG00000276876 PMC10757967__F3 Advances in the regulatory mechanisms of mTOR in necroptosis ENSG00000137275 ENSG00000102871 ENSG00000198793 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000064012 ENSG00000285379 PMC10757967__F2 Advances in the regulatory mechanisms of mTOR in necroptosis ENSG00000124256 ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000154124 ENSG00000127191 ENSG00000133116 ENSG00000136869 ENSG00000083799 ENSG00000168404 ENSG00000064012 ENSG00000285379 ENSG00000026103 ENSG00000164342 PMC5547476__F9 Cartoon depicts the role of MYBL2 and FoxM1 in glioma progression ENSG00000087245 ENSG00000170558 ENSG00000101057 ENSG00000123374 PMC10757967__F1 Advances in the regulatory mechanisms of mTOR in necroptosis ENSG00000101407 ENSG00000143761 ENSG00000155792 ENSG00000274070 PMC8750056__F2 Genetic Mutations of Pancreatic Cancer and Genetically Engineered Mouse Models ENSG00000124102 PMC5306280__F1 Activation of the canonical NFKB pathway ENSG00000291603 ENSG00000124181 ENSG00000175104 ENSG00000127191 PMC7250567__F6 Proposed model of K. pneumoniae-stimulated signaling pathway ENSG00000198053 PMC2695202__F2 Emerging anti-inflammatory therapy ENSG00000108691 ENSG00000163739 ENSG00000196591 ENSG00000124107 ENSG00000121807 PMC7957534__F3 Role and regulation of CTHRC1 in canonical and noncanonical Wnt signaling ENSG00000164932 ENSG00000169071 ENSG00000100592 ENSG00000134982 ENSG00000172269 ENSG00000168036 PMC7957534__F2 CTHRC1 modulating collagen deposition and vascular repair following injury through the TGFB signaling pathway ENSG00000164932 PMC9261164__F2 Pleiotropic effects of cell competition between normal and transformed cells in mammalian cancers ENSG00000142627 ENSG00000204577 ENSG00000163914 ENSG00000267534 PMC6817417__F1 PI3K/Akt signaling pathway regulated by PTEN ENSG00000198793 PMC5157014__F3 Microcystin-Leucine Arginine Causes Cytotoxic Effects in Sertoli Cells Resulting in Reproductive Dysfunction in Male Mice ENSG00000203734 ENSG00000163832 ENSG00000127533 ENSG00000157211 ENSG00000130287 ENSG00000160336 ENSG00000148798 ENSG00000128610 ENSG00000076641 ENSG00000118997 ENSG00000155508 ENSG00000155657 PMC484174__F8 A testable model for the modulating role of Dcs1 in the yeast stress response ENSG00000111341 ENSG00000172795 PMC2692634__F1 THE ENZYMES OF THE 10-FORMYL-TETRAHYDROFOLATE SYNTHETIC PATHWAY ARE FOUND EXCLUSIVELY IN THE CYTOSOL OF THE TRYPANOSOMATID PARASITE LEISHMANIA MAJOR ENSG00000065911 ENSG00000100714 PMC11658190__F2 Functions of the Ddx family in the development, differentiation, and homeostasis of oligodendrocytes ENSG00000123064 ENSG00000197971 ENSG00000108654 PMC7868698__F2 Deep Look into the Program of Rapid Tumor Growth of Hepatocellular Carcinoma ENSG00000077935 ENSG00000149311 ENSG00000090402 ENSG00000136997 ENSG00000143839 ENSG00000115942 ENSG00000139687 PMC9155226__F1 Trimming the fat: is there a health economic case for the use of new lipid-lowering drugs in chronic kidney disease? A scoping review ENSG00000130164 ENSG00000198670 ENSG00000160179 PMC11658190__F4 Dual inhibition mechanism of the p53 pathway by Olig2 ENSG00000142252 ENSG00000152147 ENSG00000046647 ENSG00000092208 ENSG00000205927 PMC10610144__F7 SBP effects on BMP2-Smad1/5/9-Runx2 signaling pathway ENSG00000170365 ENSG00000113140 ENSG00000120693 PMC9178561__F6 First study on the effect of crocodile oil from Crocodylus siamensis on hepatic mitochondrial function for energy homeostasis in rats ENSG00000131473 ENSG00000198793 ENSG00000119431 ENSG00000164327 ENSG00000108443 ENSG00000141564 ENSG00000001626 ENSG00000187840 PMC2897911__F1 Induction of Type I Interferons by Bacteria ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC6337367__F1 Kinases in the insulin signaling cascades and its interaction with nutrients in control of FOXO1-mediated physiological function ENSG00000147162 ENSG00000169047 PMC9513079__F2 Interaction between LSC and BMM ENSG00000178860 ENSG00000107562 ENSG00000198793 ENSG00000026508 ENSG00000121966 PMC6429987__F2 AMPK-mTOR signaling pathways during Mtb infection ENSG00000177169 ENSG00000167207 ENSG00000198793 ENSG00000112561 ENSG00000237693 PMC6429987__F1 Brief summary of reciprocal regulation between AMPK and mTOR pathways ENSG00000198793 PMC7349502__F2 N-glycan trimming of the HBV envelope glycoproteins ENSG00000134109 ENSG00000116406 ENSG00000088298 PMC7434793__F1 Resistance to BRAF-targeted therapy ENSG00000157764 ENSG00000138798 ENSG00000198793 ENSG00000122778 ENSG00000146648 PMC7232129__F7 HBV-miR-3 activation of innate immunity to restrain HBV replication ENSG00000089127 ENSG00000115415 ENSG00000157601 ENSG00000142166 PMC4590661__F3 Regulation of autophagy by the MTORC1 signaling pathway in cancer cells ENSG00000149311 ENSG00000177169 ENSG00000123395 ENSG00000023287 ENSG00000284099 ENSG00000112561 ENSG00000155876 ENSG00000103257 ENSG00000025039 ENSG00000115419 ENSG00000083750 PMC5716985__F1 Mechanism of epithelial-to-mesenchymal transition (EMT) ENSG00000019991 ENSG00000176692 ENSG00000138798 ENSG00000170558 ENSG00000168036 PMC8319800__F3 Do changes in microglial status underlie neurogenesis impairments and depressive-like behaviours induced by psychological stress? A systematic review in animal models ENSG00000162711 ENSG00000077279 ENSG00000189403 PMC8491217__F2 Lipid metabolism in cancer progression and therapeutic strategies ENSG00000131473 ENSG00000096088 ENSG00000169710 ENSG00000150457 ENSG00000131023 PMC5834531__F6 This figure summarizes the central s-resistin downregulation effects on hypothalamic and peripheral insulin and leptin sensitivity ENSG00000169047 ENSG00000115138 ENSG00000168610 PMC9062983__F1 Effect of Fluoride on Cytotoxicity Involved in Mitochondrial Dysfunction: A Review of Mechanism ENSG00000162711 ENSG00000073578 ENSG00000171791 ENSG00000084774 PMC8232269__F4 One Hundred Candidate Genes and Their Roles in Drought and Salt Tolerance in Wheat ENSG00000173599 PMC7105613__F1 Tryptophan catabolic pathway ENSG00000162882 ENSG00000188676 PMC8789279__F7 Schematics for the BNP-NPRC facilitated signaling pathway and distinct neuropeptide pathways for histamine-dependent and -independent itch ENSG00000078747 ENSG00000291631 ENSG00000135577 PMC7246682__F6 Action of fractalkine on JEG-3 trophoblast cells Fractalkine binds to its cognate receptor on the surface of trophoblast cells activating MAPK and AKT pathways ENSG00000087245 ENSG00000168329 ENSG00000100985 PMC6029864__F1 Notch signaling on T cells ENSG00000283780 ENSG00000134982 ENSG00000163599 PMC11535288__F7 Overall metabolic pathways altered in systemic (plasma) and lung tissue of OVA-induced asthma mice after BS012 administration ENSG00000042832 ENSG00000173599 PMC7905103__F5 Diagram depicting a potential mechanism of interactions ENSG00000170458 ENSG00000136869 ENSG00000101425 PMC11722561__F1 Recent Updates and Advances in the Association Between Vitamin D Deficiency and Risk of Thrombotic Disease ENSG00000205221 ENSG00000132693 PMC8137704__F4 Whole transcriptome RNA-seq reveals key regulatory factors involved in type 2 diabetes pathology in peripheral fat of Asian Indians ENSG00000109819 ENSG00000171720 ENSG00000116044 ENSG00000135446 ENSG00000064393 ENSG00000123374 ENSG00000129152 ENSG00000101266 ENSG00000116030 ENSG00000131910 PMC2859933__F9 Evidence for Alteration of Gene Regulatory Networks through MicroRNAs of the HIV-Infected Brain: Novel Analysis of Retrospective Cases ENSG00000143420 ENSG00000292357 PMC6948367__F3 Alternative STING pathway activation ENSG00000149311 ENSG00000125347 ENSG00000175104 PMC11879837__F10 Illustration of the JAK2/STAT3 and PI3K/AKT signaling pathways implicated in the protective effect of SM on kidneys injured by DN ENSG00000198793 ENSG00000168610 PMC6948367__F2 Canonical STING pathway activation ENSG00000169245 ENSG00000183735 ENSG00000164430 ENSG00000163565 ENSG00000277943 PMC4121105__F1 KEAP1/CUL3/RBX1 E3-ligase protein complex ENSG00000100387 ENSG00000079999 PMC6948367__F1 Homologous recombination repair pathway (adapted from De Picciotto et al.) ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000136492 ENSG00000083093 ENSG00000051180 ENSG00000112130 ENSG00000139618 PMC3298518__F2 Pathogenesis of neurodegenerative diseases is significantly associated with oxidative stress ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC3973444__F7 Alterations in the levels of vesicular trafficking proteins involved in HIV replication in the brains and CSF of patients with HIV-associated neurocognitive disorders ENSG00000130724 ENSG00000176108 ENSG00000187608 ENSG00000074319 ENSG00000086065 PMC6885354__F4 Analysis of miRNA expression profiles in the liver of Clock-delta19 mutant mice ENSG00000121989 ENSG00000111049 ENSG00000165030 ENSG00000148926 ENSG00000108654 ENSG00000164327 ENSG00000105085 ENSG00000162772 ENSG00000124762 ENSG00000163251 ENSG00000150907 ENSG00000179348 ENSG00000155760 ENSG00000280548 ENSG00000166167 ENSG00000138795 ENSG00000142192 ENSG00000090104 ENSG00000170027 ENSG00000143878 ENSG00000197102 ENSG00000110680 ENSG00000065559 ENSG00000157106 ENSG00000108510 ENSG00000132170 ENSG00000164742 ENSG00000156802 ENSG00000110395 ENSG00000172602 ENSG00000006451 ENSG00000107485 ENSG00000164292 ENSG00000182389 ENSG00000198829 ENSG00000050748 ENSG00000095015 ENSG00000169032 ENSG00000104332 ENSG00000169967 ENSG00000157557 ENSG00000028839 ENSG00000185591 ENSG00000083642 ENSG00000170214 ENSG00000101057 ENSG00000174804 ENSG00000182621 ENSG00000036828 ENSG00000133216 ENSG00000071564 ENSG00000007168 ENSG00000101972 ENSG00000117020 ENSG00000116106 ENSG00000177606 ENSG00000142731 ENSG00000131196 ENSG00000114166 ENSG00000163930 ENSG00000160551 ENSG00000123728 ENSG00000142453 ENSG00000150681 ENSG00000138755 ENSG00000066027 ENSG00000148400 ENSG00000174705 ENSG00000116717 ENSG00000123219 ENSG00000124216 ENSG00000291754 ENSG00000122952 ENSG00000143507 ENSG00000156127 ENSG00000177200 ENSG00000213694 ENSG00000096717 ENSG00000130669 ENSG00000019991 ENSG00000140575 ENSG00000116791 ENSG00000104833 ENSG00000176105 ENSG00000181555 ENSG00000118971 ENSG00000196396 ENSG00000072571 ENSG00000174136 ENSG00000153147 ENSG00000118515 ENSG00000132326 ENSG00000291761 ENSG00000179094 ENSG00000137834 ENSG00000027075 ENSG00000171105 ENSG00000177971 ENSG00000275835 ENSG00000198042 ENSG00000186867 ENSG00000072803 ENSG00000147145 ENSG00000152455 ENSG00000185532 ENSG00000164754 PMC3574816__F1 Polyamines as mediators of APC-dependent intestinal carcinogenesis and cancer chemoprevention ENSG00000134982 ENSG00000168036 PMC7403467__F1 Quantification of CpG Motifs in rAAV Genomes: Avoiding the Toll ENSG00000239732 ENSG00000111537 ENSG00000113520 ENSG00000172936 PMC5148003__F1 AM251 Suppresses Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells ENSG00000087245 ENSG00000138795 ENSG00000108821 PMC5082787__F10 Schematic illustration of Ro inhibiting autophagic flux and sensitizing chemoresistant esophageal cancer cells to 5-Fu-induced cell death ENSG00000158517 ENSG00000149554 PMC9166453__F2 Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases ENSG00000070831 ENSG00000198793 ENSG00000163914 PMC5864191__F2 Mevalonate pathway and mutp53 ENSG00000160752 ENSG00000110921 ENSG00000163914 ENSG00000167508 PMC3583581__F2 Recent advances in prostate development and links to prostatic diseases ENSG00000087245 ENSG00000164690 ENSG00000104332 ENSG00000128602 PMC8616517__F3 Kinase Inhibitors’ Effects on Innate Immunity in Solid Cancers ENSG00000134982 PMC8900217__F2 DNA Damage and Activation of cGAS/STING Pathway Induce Tumor Microenvironment Remodeling ENSG00000102962 ENSG00000164430 ENSG00000134982 PMC3146975__F3 Coordinate Regulation of mRNA Decay Networks by GU-rich Elements and CELF1 ENSG00000128310 ENSG00000150594 ENSG00000070831 ENSG00000123411 ENSG00000171049 ENSG00000178209 ENSG00000127955 ENSG00000196220 ENSG00000166006 ENSG00000121966 ENSG00000169715 ENSG00000065135 ENSG00000123268 PMC8900217__F1 DNA Damage and Activation of cGAS/STING Pathway Induce Tumor Microenvironment Remodeling ENSG00000183735 ENSG00000164430 PMC5864191__F4 Functional association between mutp53 and mevalonate pathway-associated oncogenic proteins (Ras, RhoA, YAP/TAZ) ENSG00000146648 PMC3146975__F1 Coordinate Regulation of mRNA Decay Networks by GU-rich Elements and CELF1 ENSG00000107338 ENSG00000213658 ENSG00000291971 ENSG00000010810 ENSG00000184371 ENSG00000095794 ENSG00000108061 PMC9357935__F2 Research Progress of Myocardial Fibrosis and Atrial Fibrillation ENSG00000172936 ENSG00000136869 PMC10387486__F4 Cellular mechanotransduction in health and diseases: from molecular mechanism to therapeutic targets ENSG00000170365 ENSG00000164828 ENSG00000105329 ENSG00000277222 ENSG00000103335 PMC9281132__F2 Wnt signaling in colorectal cancer: pathogenic role and therapeutic target ENSG00000101282 ENSG00000281324 ENSG00000134982 ENSG00000168036 ENSG00000108375 ENSG00000166526 PMC11578537__F7 Iron-dependent hepatic regulation of hepcidin ENSG00000010704 ENSG00000106327 ENSG00000105697 ENSG00000168610 PMC3583581__F4 Recent advances in prostate development and links to prostatic diseases ENSG00000129514 ENSG00000164690 PMC4172644__F1 Geographical and ethnic distribution of single nucleotide polymorphisms within genes of the folate/homocysteine pathway metabolism ENSG00000086205 ENSG00000100714 ENSG00000205221 ENSG00000173638 ENSG00000124275 ENSG00000185339 ENSG00000116984 PMC1601945__F1 Model of RNF11 interactions in the TGFB receptor signaling pathway ENSG00000123091 PMC2685981__F1 Gene Expression Profiling of Lymphoblasts from Autistic and Nonaffected Sib Pairs: Altered Pathways in Neuronal Development and Steroid Biosynthesis ENSG00000125166 ENSG00000115008 ENSG00000135218 ENSG00000143013 ENSG00000158195 ENSG00000163565 ENSG00000173039 ENSG00000178104 ENSG00000010278 ENSG00000121966 ENSG00000171502 ENSG00000073060 ENSG00000144802 ENSG00000067606 ENSG00000169696 ENSG00000157087 ENSG00000173599 ENSG00000113520 ENSG00000136869 ENSG00000185591 ENSG00000078098 ENSG00000110987 ENSG00000189067 PMC5979336__F10 Scheme of possible signaling pathways involved in regulating the functional state of Cx43 HCs, Panx1 Chs, P2X7Rs and Cx GJs in mesangial cells stimulated with AngII ENSG00000125538 ENSG00000110218 PMC12188374__F2 (1) Treatment with EGFR-TKI or KRAS inhibitors may lead to AST ENSG00000163734 ENSG00000168610 PMC12188374__F1 (1) The EML4-ALK fusion protein produced by ALK rearrangement can activate the JAK-STAT signaling pathway ENSG00000169554 ENSG00000136997 ENSG00000163734 ENSG00000129514 ENSG00000136352 ENSG00000136451 ENSG00000168610 PMC7166227__F3 Different mechanisms are triggered when stimulated by the different nucleotides in the CeCa TME ENSG00000146648 PMC2685981__F3 Gene Expression Profiling of Lymphoblasts from Autistic and Nonaffected Sib Pairs: Altered Pathways in Neuronal Development and Steroid Biosynthesis ENSG00000019991 ENSG00000105329 ENSG00000291971 ENSG00000108342 ENSG00000110651 ENSG00000010278 ENSG00000163737 ENSG00000121966 ENSG00000132170 ENSG00000073060 ENSG00000144802 ENSG00000163235 ENSG00000125538 ENSG00000115138 ENSG00000164136 ENSG00000113520 ENSG00000107485 ENSG00000164690 ENSG00000113525 PMC5228603__F3 Reparative inflammation takes charge of tissue regeneration ENSG00000154342 ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000185483 ENSG00000168036 ENSG00000150457 ENSG00000168610 ENSG00000131023 PMC4357208__F1 Metabolic network for flux analysis ENSG00000122966 ENSG00000172005 ENSG00000167900 PMC5829655__F1 Hypothetical model summarizing the probable mechanisms of severe inflammation in malaria ENSG00000125538 ENSG00000107485 ENSG00000172936 ENSG00000131323 PMC1526546__F1 Innate model of lupus pathogenesis: central role of TLR-activated MZ-B cells and pDCs ENSG00000239732 PMC4196647__F2 E-cadherin on RTK signalling ENSG00000115415 ENSG00000146648 ENSG00000178568 PMC6336458__F1 Molecular mechanisms of viral oncogenesis in humans ENSG00000283780 ENSG00000134982 ENSG00000186716 ENSG00000136869 ENSG00000175104 ENSG00000137845 ENSG00000184216 PMC3887674__F1 Factors influencing the reprogramming of unipotent SSCs into pluripotent stem cells ENSG00000141384 ENSG00000188425 PMC8866866__F1 Nerve Dependence in Colorectal Cancer ENSG00000137673 ENSG00000170558 ENSG00000100985 ENSG00000146648 PMC8517930__F7 Novel insights into the regulation of LATS2 kinase in prehierarchical follicle development via the Hippo pathway in hen ovary ENSG00000101109 ENSG00000007866 ENSG00000150457 PMC3788359__F3 Pathways linking hypoxia to CSCs and EMT in tumor aggressiveness ENSG00000169554 PMC7059351__F2 Alteration of synthesis and degradation pathways of glycosphingolipids in the physiopathology of HSP ENSG00000135454 ENSG00000070610 PMC6805914__F7 EPHB4 inhibition activates ER stress to promote immunogenic cell death of prostate cancer cells ENSG00000196411 ENSG00000144895 ENSG00000291971 ENSG00000136997 PMC4476649__F1 Regulation of Lymphocyte Function by Adenosine ENSG00000158473 ENSG00000113520 ENSG00000049768 PMC4088370__F3 KEGG Cell-cycle pathway ENSG00000145604 ENSG00000132646 ENSG00000164754 ENSG00000277273 ENSG00000276876 PMC6627635__F3 Predicted/established targets of selective flavonoids in platelets: Flavonoids modulate platelet activation through multiple mechanisms ENSG00000213658 ENSG00000010810 PMC4088370__F2 KEGG MAPK signalling pathway ENSG00000113905 ENSG00000170458 ENSG00000130159 ENSG00000196712 ENSG00000026103 PMC11280061__F6 Auxin-regulated TFRN attenuates lignin biosynthesis ENSG00000171735 ENSG00000113430 ENSG00000121807 PMC9204003__F2 Long Noncoding RNA and Circular RNA: Two Rising Stars in Regulating Epithelial-Mesenchymal Transition of Pancreatic Cancer ENSG00000162711 ENSG00000187240 ENSG00000171150 ENSG00000115415 ENSG00000253352 ENSG00000077782 ENSG00000146648 ENSG00000251493 PMC11280061__F7 Auxin-regulated TFRN attenuates ABA transport, conjugation and signaling ENSG00000211445 ENSG00000171735 ENSG00000108798 PMC3415708__F5 Novel fumarate hydratase-deficient HLRCC kidney cancer cell line, UOK268: a model of the Warburg effect in cancer ENSG00000100412 ENSG00000105953 ENSG00000105607 ENSG00000100294 ENSG00000127884 PMC3415708__F4 A novel fumarate hydratase-deficient HLRCC kidney cancer cell line, UOK268: a model of the Warburg effect in cancer ENSG00000142192 ENSG00000105953 PMC4088370__F4 KEGG Apoptosis pathway ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC7063119__F1 Apelin/APJ system–mediated signaling pathways ENSG00000127528 ENSG00000108840 PMC12208858__F2 Intravascular release and mechanism of pH-responsive TwHF nanocarrier ENSG00000162692 ENSG00000168610 PMC3568227__F2 Role of mesothelin in cancer progressionOverexpression of mesothelin leads to higher IL-6 production by constitutively activating NFKB ENSG00000002330 ENSG00000123374 ENSG00000102854 ENSG00000168610 PMC3088358__F7 The extracellular network of proteins that control D–V patterning PMC305326__F1 The development, activation, and maintenance of the satellite cell ENSG00000009709 ENSG00000019991 ENSG00000111049 PMC4273559__F2 KEGG pathways significantly associated with NPG ENSG00000162552 ENSG00000112972 ENSG00000115904 ENSG00000081189 ENSG00000075429 ENSG00000151348 ENSG00000114738 ENSG00000127884 ENSG00000072210 ENSG00000075461 ENSG00000170458 ENSG00000164161 ENSG00000169750 ENSG00000243708 ENSG00000285395 ENSG00000010810 ENSG00000130222 ENSG00000113790 ENSG00000275544 PMC3554567__F4 Integration of Nodal and BMP Signals in the Heart Requires FoxH1 to Create Left–Right Differences in Cell Migration Rates That Direct Cardiac Asymmetry ENSG00000160973 ENSG00000156574 PMC5423040__F2 Hunger-satiety circuit and energy balance ENSG00000171105 ENSG00000198576 ENSG00000115138 ENSG00000166603 ENSG00000121853 ENSG00000131096 PMC8906956__F8 Postconditioning with Irisin Attenuates Lung Ischemia/Reperfusion Injury by Suppressing Ferroptosis via Induction of the Nrf2/HO-1 Signal Axis ENSG00000168003 ENSG00000151012 ENSG00000167468 PMC4273559__F3 Butanonate metabolic pathway (KEGG pathway hsa00650) ENSG00000183549 ENSG00000164904 ENSG00000112972 ENSG00000087299 ENSG00000120437 ENSG00000131828 ENSG00000215009 ENSG00000127884 ENSG00000066813 ENSG00000163114 ENSG00000072210 ENSG00000143149 ENSG00000198754 ENSG00000005187 ENSG00000164039 ENSG00000083720 ENSG00000122971 ENSG00000075239 ENSG00000113790 ENSG00000275544 ENSG00000183747 ENSG00000117305 PMC4929427__F2 Cross-talk of mammalian Hippo signalling with the MAPK, PI3K and intrinsic and extrinsic apoptotic pathways ENSG00000149311 ENSG00000175054 ENSG00000132471 ENSG00000126016 ENSG00000156709 ENSG00000168036 ENSG00000171791 ENSG00000140464 PMC5954090__F7 The metabolic characteristics of a low-carnitine zebrafish model ENSG00000171105 ENSG00000198793 PMC8804323__F1 FGF19 and MALRD1 in Enterohepatic Bile Acid Signaling ENSG00000167910 ENSG00000180432 ENSG00000099377 ENSG00000135929 PMC7242447__F3 Genetic variation and evolutionary history of a mycorrhizal fungus regulate the currency of exchange in symbiosis with the food security crop cassava ENSG00000113456 ENSG00000173599 ENSG00000198670 ENSG00000131828 ENSG00000091140 ENSG00000062485 PMC4061845__F2 Sphingolipid involvement in ethanol-induced apoptosis in the P7 mouse brain ENSG00000063176 ENSG00000170989 PMC7326156__F7 Newcastle Disease virus infection activates PI3K/Akt/mTOR and p38 MAPK/Mnk1 pathways to benefit viral mRNA translation via interaction of the viral NP protein and host eIF4E ENSG00000198793 PMC9178120__F5 Contribution of the Tumor Microenvironment to Metabolic Changes Triggering Resistance of Multiple Myeloma to Proteasome Inhibitors ENSG00000151012 ENSG00000092621 ENSG00000165280 PMC2413330__F3 Working hypothesis on the mechanism by which plasminogen activator inhibitor-1 (PAI-1) causes hepatic steatosis ENSG00000019991 ENSG00000138823 PMC9178120__F4 Contribution of the Tumor Microenvironment to Metabolic Changes Triggering Resistance of Multiple Myeloma to Proteasome Inhibitors ENSG00000135423 ENSG00000101146 ENSG00000111371 PMC9178120__F2 Contribution of the Tumor Microenvironment to Metabolic Changes Triggering Resistance of Multiple Myeloma to Proteasome Inhibitors ENSG00000019991 ENSG00000179934 ENSG00000026751 ENSG00000162692 ENSG00000121966 ENSG00000140443 PMC8920443__F37 2022 WHO Classification of Adrenal Cortical Tumors ENSG00000067842 ENSG00000163399 ENSG00000196557 ENSG00000185231 PMC11005288__F5 Compound Shenma Jingfu granule alleviates cerebral ischemia via HIF-1Alpha-mediated promotion of angiogenesis ENSG00000134086 ENSG00000198793 ENSG00000072274 ENSG00000198517 ENSG00000136869 PMC8721229__F4 Differential Effects of Propylthiouracil and Methimazole as Graves’ Disease Treatment on Vascular Atherosclerosis Markers: A Randomized Clinical Trial ENSG00000162692 PMC4371960__F6 E2-induced signal transduction pathways in the uterine epithelium leading to DNA and protein synthesis ENSG00000198793 ENSG00000140443 PMC5877395__F1 Annexin A2 (ANXA2) in cancer progression ENSG00000182718 ENSG00000197747 ENSG00000170558 ENSG00000122194 ENSG00000141741 PMC8533518__F1 Enhancement of Beta-Alanine Biosynthesis in Escherichia coli Based on Multivariate Modular Metabolic Engineering ENSG00000122966 ENSG00000172005 PMC6006330__F8 BMP2/4 increase neurogenesis from adult hippocampal NSPCs and synergize with WNT3A ENSG00000107779 ENSG00000138795 PMC5622154__F2 Differentially expressed genes upon congenital neonatal human cytomegalovirus (HCMV) infection form distinct subnetworks ENSG00000167671 ENSG00000250361 ENSG00000158578 ENSG00000180644 ENSG00000100225 ENSG00000134321 ENSG00000184792 ENSG00000136908 ENSG00000178719 ENSG00000162722 ENSG00000132819 ENSG00000117228 ENSG00000198336 ENSG00000063854 ENSG00000100450 ENSG00000137198 ENSG00000166947 ENSG00000162654 ENSG00000108309 ENSG00000105374 ENSG00000154451 ENSG00000197465 ENSG00000185883 ENSG00000198858 ENSG00000115415 ENSG00000159346 ENSG00000099804 ENSG00000004939 PMC12222446__F1 Polyamines at the crossroad between cell metabolism and epigenetic regulation in acute leukemias ENSG00000168003 ENSG00000081181 ENSG00000088826 ENSG00000063660 ENSG00000148832 ENSG00000099810 ENSG00000118520 ENSG00000123505 ENSG00000100033 ENSG00000116649 ENSG00000102172 ENSG00000115419 PMC3395153__F1 Roles of Platelets and the Signal Transductions Identified as the Major Cascades in Hepatocyte Proliferation ENSG00000019991 ENSG00000163235 ENSG00000198793 ENSG00000168610 PMC5661633__F2 NFKB in the regulation of NLRP3 inflammasome ENSG00000162711 ENSG00000125538 ENSG00000172936 ENSG00000175104 PMC9647118__F2 Homologous recombination ENSG00000083093 ENSG00000051180 ENSG00000139618 PMC12222446__F5 Polyamines at the crossroad between cell metabolism and epigenetic regulation in acute leukemias ENSG00000081181 ENSG00000088826 ENSG00000148832 ENSG00000099810 ENSG00000118520 ENSG00000123505 ENSG00000116649 ENSG00000102172 PMC4673348__F5 Proposed schematic showing targets of SA transcriptional regulation of insulin signaling pathway ENSG00000171105 ENSG00000067606 ENSG00000198793 PMC9368916__F3 Comparative Transcriptome Analysis Reveals Coordinated Transcriptional Regulation of Central and Secondary Metabolism in the Trichomes of Cannabis Cultivars ENSG00000180447 ENSG00000197429 ENSG00000167508 PMC6913448__F1 Structures of CLEC-2 and podoplanin ENSG00000213658 ENSG00000291971 ENSG00000010671 PMC4134368__F2 Biosynthesis of spiruchostatins ENSG00000269404 ENSG00000166278 ENSG00000145020 PMC2844056__F7 Genes involved in cell-cell signaling significantly associated with ERbreast cancer cells in response to AA ENSG00000132906 ENSG00000101955 ENSG00000230930 ENSG00000002330 ENSG00000169857 ENSG00000091592 ENSG00000105483 ENSG00000170367 PMC2844056__F6 Insulin receptor cascade was uniquely up regulated in ER− cells when treated with AA ENSG00000159200 ENSG00000185652 ENSG00000170961 ENSG00000226275 ENSG00000119535 ENSG00000137265 ENSG00000113520 ENSG00000269404 ENSG00000112715 ENSG00000121774 ENSG00000076604 ENSG00000169575 PMC2844056__F5 Ingenuity pathway analysis of genes up regulated in ER+ cell in response to AA shows that the ERK/MEK pathway was significantly associated with ER+ ENSG00000002330 ENSG00000109654 ENSG00000168610 PMC2844056__F2 Ingenuity pathway analysis and expression profiles of genes involved in apoptosis that were uniquely up regulated in ER+ cells in response to EPA ENSG00000115415 ENSG00000146247 ENSG00000164754 ENSG00000130255 ENSG00000177425 PMC4052811__F2 Deduced pathway of sterol biosynthesis in N ENSG00000116133 ENSG00000197429 ENSG00000128602 PMC3114846__F5 Gene-Disease Network Analysis Reveals Functional Modules in Mendelian, Complex and Environmental Diseases ENSG00000004846 ENSG00000111796 ENSG00000078399 ENSG00000101440 ENSG00000080166 ENSG00000213809 ENSG00000136874 ENSG00000170178 PMC11674819__F2 PD-1/PD-L1 signaling pathway ENSG00000134982 PMC8591899__F1 SARS-CoV-2 infection and oxidative stress: Pathophysiological insight into thrombosis and therapeutic opportunities ENSG00000169245 ENSG00000108691 ENSG00000088888 ENSG00000111537 ENSG00000130234 ENSG00000184012 ENSG00000113520 PMC11576170__F3 The ICE1-CBF-COR signaling cascade ENSG00000164151 ENSG00000110934 ENSG00000140451 PMC8591899__F5 SARS-CoV-2 infection and oxidative stress: Pathophysiological insight into thrombosis and therapeutic opportunities ENSG00000178573 ENSG00000079999 PMC11576170__F2 Perception and transduction of cold signals in plants ENSG00000164151 ENSG00000136152 ENSG00000110395 PMC6857111__F11 Huaier inhibited breast cancer progression through linc00339/miR-4656/CSNK2B signaling pathway PMC11576170__F4 ROS homeostasis regulates plant cold tolerance ENSG00000120438 PMC9016203__F5 Therapeutic Applications of Physalins: Powerful Natural Weapons ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000128602 ENSG00000168610 PMC9025601__F3 Epigenome-Wide Analysis of DNA Methylation in Parkinson’s Disease Cortex ENSG00000078900 ENSG00000130649 PMC8518235__F8 Endometrial regenerative cells with galectin-9 high-expression attenuate experimental autoimmune hepatitis ENSG00000069482 ENSG00000213658 PMC8245853__F2 CD8+ T lymphocyte cells: Interplay with stromal cells in tumor microenvironment ENSG00000094631 ENSG00000107562 ENSG00000162493 ENSG00000112715 ENSG00000121966 ENSG00000169245 ENSG00000089692 ENSG00000133048 ENSG00000115415 ENSG00000138755 ENSG00000276051 ENSG00000184371 ENSG00000164690 ENSG00000026103 PMC6680919__F4 Leptin signaling ENSG00000115138 ENSG00000168610 PMC2978002__F7 Model demonstrating the specific apoptotic effect of SREBP-1 and FAS inhibition on GBM cells bearing EGFRvIII ENSG00000198793 ENSG00000146648 ENSG00000026103 PMC11004450__F6 Single cell and bulk RNA expression analyses identify enhanced hexosamine biosynthetic pathway and O-GlcNAcylation in acute myeloid leukemia blasts and stem cells ENSG00000100522 ENSG00000147162 ENSG00000198408 ENSG00000124357 ENSG00000013375 PMC9601999__F4 Genes Related to Cognition after tDCS in an Intermittent Hypoxic Brain Injury Rat Model ENSG00000169291 ENSG00000107338 ENSG00000070831 ENSG00000173156 PMC5302168__F8 Transcriptional regulation of SPROUTY 2 by MYB influences myeloid cell proliferation and stem cell properties by enhancing responsiveness to IL-3 ENSG00000136158 ENSG00000198793 ENSG00000155903 PMC6279925__F4 Network visualization of top primary hits ENSG00000169071 ENSG00000117425 ENSG00000171723 ENSG00000205302 ENSG00000197272 ENSG00000104885 ENSG00000110931 ENSG00000112715 ENSG00000100385 ENSG00000108578 ENSG00000113456 ENSG00000166263 ENSG00000167779 ENSG00000173578 ENSG00000047230 ENSG00000116030 ENSG00000187210 ENSG00000291608 ENSG00000105662 ENSG00000130513 ENSG00000123700 ENSG00000185022 ENSG00000152495 ENSG00000163453 ENSG00000105953 ENSG00000173610 ENSG00000112874 ENSG00000154016 ENSG00000075073 ENSG00000110719 ENSG00000131944 ENSG00000143315 ENSG00000069018 ENSG00000078579 ENSG00000104290 ENSG00000183864 ENSG00000099804 ENSG00000128602 PMC2685661__F10 NO/cGMP and calcium signaling in osteoblast mechanotransduction ENSG00000125740 PMC9175095__F8 Exosomal CTCF Confers Cisplatin Resistance in Osteosarcoma by Promoting Autophagy via the IGF2-AS/miR-579-3p/MSH6 Axis ENSG00000102974 PMC5649483__F1 Showing a putative Th17/Treg/Th1/Th2 regulatory axis ENSG00000107485 ENSG00000049768 PMC8921682__F3 Decline in Liver Mitochondria Metabolic Function Is Restored by Hochuekkito Through Sirtuin 1 in Aged Mice With Malnutrition ENSG00000095321 ENSG00000167910 ENSG00000016391 PMC5436301__F1 DNA repair pathways in mammalian cells ENSG00000143799 ENSG00000012061 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000138346 ENSG00000080345 ENSG00000051180 ENSG00000177084 ENSG00000136936 ENSG00000138385 ENSG00000139618 PMC5436301__F2 Interstrand crosslinks can be repaired by replication-independent (left) and replication-dependent (right) mechanisms ENSG00000131944 ENSG00000012048 ENSG00000175054 ENSG00000188827 ENSG00000187790 ENSG00000122008 PMC11004450__F1 Single cell and bulk RNA expression analyses identify enhanced hexosamine biosynthetic pathway and O-GlcNAcylation in acute myeloid leukemia blasts and stem cells ENSG00000100522 ENSG00000147162 ENSG00000198408 ENSG00000124357 ENSG00000013375 PMC5436301__F6 Repression of or mutation in several upstream regulators of homologous recombination (HR) can be synthetically lethal with PARP1 inhibition because they can cause a variety of HR repair defects that prevent fork restart ENSG00000143799 ENSG00000188486 ENSG00000102226 ENSG00000165392 ENSG00000197299 ENSG00000051180 ENSG00000177084 PMC7260582__F1 Action of cetuximab, encorafenib and binimetinib ENSG00000019991 ENSG00000138798 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC12004712__F10 KEGG “Leukocyte transendothelial migration” pathwayKEGG “Leukocyte transendothelial migration” pathway highlighting the associated AC contrast DEGs ENSG00000292348 ENSG00000169896 ENSG00000166086 ENSG00000070831 ENSG00000150093 ENSG00000154721 ENSG00000115718 ENSG00000115232 ENSG00000135605 ENSG00000121966 ENSG00000154096 PMC10526380__F3 Molecular Classifiers in Skin Cancers: Challenges and Promises ENSG00000198793 ENSG00000136997 PMC11992302__F2 Six signaling pathways associated with the PD-L1 and PD-1 pathways in melanoma ENSG00000106571 ENSG00000198793 PMC8154588__F5 Synthetic lethal interactions in SWI/SNF-mutant cancers with chemical tools for targeted cancer therapy ENSG00000094631 ENSG00000175054 ENSG00000291971 ENSG00000135446 ENSG00000049618 ENSG00000105810 ENSG00000127616 ENSG00000198625 PMC3848582__F5 Schematic model demonstrating functional involvement of NPM1, RAD50 and XRCC5 in DSB-repair in the progression of ovarian cancer cells ENSG00000149311 ENSG00000079246 ENSG00000181163 PMC150381__F2 Interplay of the major genetic alteration in pancreatic carcinoma with the cell cycle ENSG00000135446 ENSG00000105810 PMC2672935__F2 Regulated molecules in canonical signalling pathways identified by IPA ENSG00000145604 ENSG00000175793 ENSG00000115415 ENSG00000105401 ENSG00000163914 ENSG00000231925 ENSG00000168040 ENSG00000127191 ENSG00000124762 PMC6766639__F4 Impact of IT on mitochondrion-related gene expression and on selected mitochondrial outcomes in tissues collected from UCD-T2DM rats at 1.5 mo-post surgery ENSG00000163624 ENSG00000088766 ENSG00000087157 ENSG00000184207 ENSG00000101290 ENSG00000062485 ENSG00000110536 PMC4553756__F3 Delta-1-pyrroline-5-carboxylate synthase (P5CS) pathway ENSG00000059573 ENSG00000118520 ENSG00000036473 PMC12130906__F2 Regulatory functions of the TGFB/Smad signaling pathway in the renal fibrosis ENSG00000102974 PMC7582884__F1 PI3K/Akt signal pathway, p53 signal pathway, and mTOR signal pathway in NPC ENSG00000102317 ENSG00000110492 ENSG00000138798 ENSG00000150907 ENSG00000198793 ENSG00000284099 ENSG00000100345 ENSG00000100526 ENSG00000135018 ENSG00000157106 ENSG00000108821 ENSG00000146648 PMC11934714__F5 HERV in the pathogenesis of ALS ENSG00000183735 ENSG00000164430 ENSG00000276561 PMC11934714__F4 HERV in schizophrenia ENSG00000168003 ENSG00000164430 ENSG00000167468 ENSG00000138741 ENSG00000149295 PMC11934714__F2 The roles of retrotransposons in adult neurogenesis ENSG00000083223 ENSG00000138336 ENSG00000176887 ENSG00000168036 ENSG00000275272 PMC5856294__F3 GPCR signaling and the organization of the stem cells niche ENSG00000152266 ENSG00000134982 ENSG00000183579 ENSG00000108375 ENSG00000168610 ENSG00000146648 PMC4872111__F1 Genes involved in CRC pathway ENSG00000132906 ENSG00000107404 ENSG00000002330 ENSG00000134982 ENSG00000168036 ENSG00000171791 ENSG00000100485 ENSG00000164305 ENSG00000157500 ENSG00000163914 ENSG00000104290 ENSG00000161202 ENSG00000095002 PMC9509228__F2 Mitochondrial-Endoplasmic Reticulum Communication-Mediated Oxidative Stress and Autophagy ENSG00000144895 ENSG00000198793 ENSG00000069509 ENSG00000127191 PMC7854732__F10 Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer ENSG00000157554 ENSG00000184012 ENSG00000121067 PMC8001237__F1 An overview of various approaches used in myostatin inhibition PMC9609640__F7 SmMYB4 Is a R2R3-MYB Transcriptional Repressor Regulating the Biosynthesis of Phenolic Acids and Tanshinones in Salvia miltiorrhiza ENSG00000197429 PMC6925860__F8 The schematic diagram depicts the mechanism of CPP-induced enhancement of sensitivity to TRAIL in ESCC cells ENSG00000168036 ENSG00000168040 ENSG00000049768 PMC4326572__F1 Main molecular pathways activated in the presence or absence of nutrients ENSG00000177169 ENSG00000110497 PMC4872111__F6 Downstream effects of miR-145 ectopic expression ENSG00000070831 ENSG00000149269 ENSG00000135446 ENSG00000123374 ENSG00000213341 ENSG00000105810 ENSG00000124762 PMC5356793__F4 Na+/H+ exchanger 1 has tumor suppressive activity and prognostic value in esophageal squamous cell carcinoma ENSG00000183011 ENSG00000070404 ENSG00000158104 ENSG00000145740 ENSG00000164007 ENSG00000113946 ENSG00000144485 ENSG00000021300 ENSG00000103351 ENSG00000108557 ENSG00000178750 ENSG00000143393 ENSG00000170310 ENSG00000171772 ENSG00000112984 ENSG00000077080 ENSG00000217442 ENSG00000134709 ENSG00000088992 ENSG00000100865 ENSG00000114739 PMC7333179__F1 Proposed estradiol-induced hypothalamic astrocyte steroidogenesis of neuroP that activates a membrane classical progesterone receptor (PGR)-Src tyrosine kinase (Src) signaling pathway in RP3V kisspeptin neurons to trigger the luteinizing (LH) surge ENSG00000082175 ENSG00000291971 ENSG00000170498 ENSG00000116014 PMC4407676__F2 The two representative networks by ingenuity pathway analysis (IPA) for differentially methylated whole gene set derived from HF-dNK-treated EVT ENSG00000160293 PMC5462754__F6 Ingenuity Pathway Analysis showing a network biology system for the interaction between both the miRNAs and the metabolites identified from the metabonomic analysis ENSG00000142192 ENSG00000171105 ENSG00000110395 ENSG00000113161 ENSG00000196914 ENSG00000120251 ENSG00000043591 ENSG00000139687 ENSG00000095794 PMC3533466__F1 Genes whose mRNA expression is suppressed by nicotine in RAW264.7 cells under poly(I:C) stimulation compared with those under poly(I:C) stimulation only are mapped to three gene networks, as predicted by ingenuity pathway analysis (IPA) ENSG00000111537 ENSG00000168040 ENSG00000150455 ENSG00000276561 PMC3155176__F4 FRAM Is Characterized by Increased Signaling of the BRAF/MEK/ERK Pathway(A) IPA analysis led to the generation of a gene-interaction network of genes differentially expressed in patients ENSG00000157764 ENSG00000100592 ENSG00000138185 ENSG00000007908 ENSG00000107551 ENSG00000144339 ENSG00000158050 PMC8909695__F2 Organic UV Filters Induce Toll-like-Receptors and Related Signaling Pathways in Peripheral Blood Mononuclear Cells of Juvenile Loggerhead Sea Turtles (Caretta caretta) ENSG00000174125 ENSG00000117020 ENSG00000167419 PMC11973847__F3 PRR signaling pathways associated with autoinflammatory diseases ENSG00000162711 ENSG00000164430 ENSG00000088888 ENSG00000137275 ENSG00000091106 PMC7640965__F1 SARS-CoV-2 infection and proliferation process mediated by host and viral proteases ENSG00000140564 ENSG00000130234 ENSG00000137648 ENSG00000184012 ENSG00000122194 PMC10137236__F1 TGFB signaling pathway PMC12025273__F6 Mechanism map of cerebral ischemia in JU ENSG00000150991 ENSG00000066044 ENSG00000177606 ENSG00000188612 ENSG00000115232 ENSG00000106459 PMC2803288__F4 Schematic diagram depicting the pathway via which GC-A signaling inhibits cardiac hypertrophy ENSG00000145321 ENSG00000117152 ENSG00000115271 PMC3533466__F5 Nicotine’s effect on multiple signal transducers in the downstream pathway of calcium ENSG00000033327 ENSG00000291971 ENSG00000149269 ENSG00000198793 ENSG00000136997 ENSG00000173402 ENSG00000146648 ENSG00000141968 ENSG00000160691 PMC5016702__F8 The signaling pathway by which FSH, via PKA, regulates the PI3K and ERK pathways in GCs ENSG00000169047 ENSG00000146648 PMC5130074__F1 Scheme depicting the possible mechanism of VEGFR-2-mediated vascular effects (cell proliferation, survival, migration, and enhanced permeability) related to vascular formation ENSG00000107338 ENSG00000002330 ENSG00000070831 ENSG00000291971 PMC5867880__F3 CD99wt and CD99sh in tumor cells ENSG00000292348 ENSG00000100985 PMC4925727__F3 Tyrosine kinase receptors and their signalling pathways involved in angiogenesis ENSG00000002330 ENSG00000291971 ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC4427058__F7 The identified epigenetic regulatory mechanism involved in the miR-124/STAT3 pathway in pediatric-UC ENSG00000171791 ENSG00000100985 ENSG00000168610 PMC8288060__F7 Canonical Wnt Signaling Drives Myopia Development and Can Be Pharmacologically Modulated ENSG00000134982 ENSG00000168036 PMC4052206__F6 Ingenuity pathway analysis (IPA) displaying regulatory relationships among highly expressed (green) and lower (red) placental transcripts in less muscular women as compared with women with high arm muscle area ENSG00000173369 ENSG00000067066 ENSG00000111537 ENSG00000173372 ENSG00000230791 ENSG00000173039 ENSG00000125347 ENSG00000230034 PMC11790818__F3 Notch signaling pathway ENSG00000140564 ENSG00000136997 PMC4292729__F1 Molecular and cellular mechanisms of immunogenic cell death ENSG00000111537 ENSG00000125538 PMC9626530__F3 Therapeutic potential of triptolide and celastrol in neurological diseases ENSG00000162711 ENSG00000137033 ENSG00000198793 ENSG00000189403 PMC9626530__F2 Therapeutic potential of triptolide and celastrol in neurological diseases ENSG00000198793 PMC6535773__F6 Dimensionality and the cell malignancy potential on lipid species amounts in the MCF10A breast cancer in vitro model ENSG00000042832 ENSG00000173599 ENSG00000119537 ENSG00000102172 PMC9161693__F1 Astrocytic Calcium and cAMP in Neurodegenerative Diseases ENSG00000196839 ENSG00000156026 PMC7914425__F5 NOD-like receptor-signaling pathway constructed based on full-length sequencing and annotation results of the skin transcriptome of a sperm whale ENSG00000088888 ENSG00000167207 ENSG00000276561 PMC5593685__F1 The reverse Warburg effect is likely to be an Achilles' heel of cancer that can be exploited for cancer therapy ENSG00000112715 PMC6824681__F10 The SGK3 signaling pathway ENSG00000100568 ENSG00000170310 ENSG00000135823 ENSG00000117758 ENSG00000079950 ENSG00000118640 PMC7595665__F3 m6A modulators involved in cardiovascular disease and bioprocess ENSG00000019991 ENSG00000112561 ENSG00000143933 ENSG00000138668 ENSG00000169180 PMC5495885__F3 MiRNA discovery ENSG00000137834 ENSG00000160973 ENSG00000157933 ENSG00000133937 ENSG00000070831 ENSG00000115297 ENSG00000198742 ENSG00000156574 ENSG00000164093 ENSG00000276561 PMC8268320__F3 TGFB Pathway: A Pharmacological Target in Hepatocellular Carcinoma? ENSG00000163599 ENSG00000164136 PMC9682260__F4 Alteration of cholesterol distribution at the plasma membrane of cancer cells: From evidence to pathophysiological implication and promising therapy strategy ENSG00000134982 ENSG00000026508 ENSG00000168040 PMC8268320__F2 TGFB Pathway: A Pharmacological Target in Hepatocellular Carcinoma? ENSG00000108691 ENSG00000161921 ENSG00000198793 ENSG00000108688 ENSG00000204520 PMC12063356__F5 Combined Ibr + AS treatment modulates both upstream and downstream effectors of the BCR (A, B) PI3K-AKT signaling pathways ENSG00000177455 ENSG00000095585 ENSG00000103479 ENSG00000101146 ENSG00000002330 ENSG00000186716 ENSG00000183979 ENSG00000145321 ENSG00000110651 ENSG00000115718 ENSG00000010671 PMC3974512__F1 Hepatitis C virus entry into hepatocytes ENSG00000130208 ENSG00000142627 ENSG00000130164 ENSG00000163914 ENSG00000015520 ENSG00000146648 ENSG00000160691 PMC8268320__F1 TGFB Pathway: A Pharmacological Target in Hepatocellular Carcinoma? ENSG00000140564 ENSG00000163914 ENSG00000086991 ENSG00000168036 ENSG00000146648 PMC7682108__F1 Intracellular cholesterol homeostasis ENSG00000138075 ENSG00000130164 ENSG00000113161 ENSG00000160179 ENSG00000143921 PMC9394213__F2 Roles and functions of SARS-CoV-2 proteins in host immune evasion ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000276561 PMC9394213__F3 Roles and functions of SARS-CoV-2 proteins in host immune evasion ENSG00000213928 ENSG00000088888 ENSG00000115415 ENSG00000110713 PMC5354945__F2 Therapeutic small-molecules target inhibitor of apoptosis proteins in cancers with deregulation of extrinsic and intrinsic cell death pathways ENSG00000104856 ENSG00000102871 ENSG00000173039 ENSG00000131323 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000164305 PMC3917351__F4 Ca2+ transport remodelling in tumour vascularization ENSG00000187688 ENSG00000092439 ENSG00000133107 ENSG00000137672 ENSG00000138741 ENSG00000119121 PMC3917351__F3 Ca2+ transport remodelling in the promotion of cancer cell metastasis ENSG00000187688 ENSG00000092439 ENSG00000165125 ENSG00000196154 ENSG00000196689 PMC3917351__F2 Ca2+ transport remodelling in conferring apoptosis resistance in cancer cells ENSG00000133107 ENSG00000144935 ENSG00000167323 ENSG00000293604 ENSG00000165125 ENSG00000196689 PMC3917351__F1 Ca2+ transport remodelling in promotion of cancer cell proliferation ENSG00000092439 ENSG00000175938 ENSG00000167323 ENSG00000293604 ENSG00000165125 ENSG00000137672 ENSG00000138741 PMC5813531__F3 Retrograde signaling during photooxidative stress in chloroplasts ENSG00000173599 ENSG00000069956 PMC4115292__F1 The one carbon (methyl group) metabolism in vivo PMC3627223__F1 The BAFF Receptor Transduces Survival Signals by Co-opting the B Cell Receptor Signaling Pathway ENSG00000077150 ENSG00000186716 PMC4590954__F5 Non-Smad signaling in response to TGFB1 and BMP-7 ENSG00000170558 ENSG00000198793 ENSG00000168036 ENSG00000175104 PMC2912210__F1 Targeting the mitogen-activated protein kinase pathway: physiological feedback and drug response ENSG00000136997 ENSG00000146648 ENSG00000196712 PMC5571864__F1 Daily Rhythm in Plasma N-Acetyltryptamine ENSG00000139287 ENSG00000129167 PMC7767853__F4 Interactions between picornavirus 2C protein and the NFKB and retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) pathways ENSG00000088888 ENSG00000167207 PMC6211389__F3 Type I interferon (IFN) gene induction by IFN regulatory factors (IRFs) on innate recognition of cytosolic nucleic acids ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000140968 ENSG00000163565 ENSG00000276561 PMC6211389__F2 Schematic view of Toll-like receptor (TLR)-mediated type I interferon (IFN) gene induction by IFN regulatory factors (IRFs) ENSG00000183735 ENSG00000239732 ENSG00000140968 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000125347 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC6581447__F2 Construction of the signaling network of cell migration regulators and their classification based on biological functions ENSG00000143549 ENSG00000070831 ENSG00000134982 ENSG00000138443 ENSG00000125733 ENSG00000149091 ENSG00000100852 ENSG00000139926 ENSG00000237693 ENSG00000150787 ENSG00000167613 ENSG00000117020 ENSG00000172725 ENSG00000163914 ENSG00000168546 ENSG00000137265 ENSG00000143322 ENSG00000154162 ENSG00000118257 ENSG00000130669 ENSG00000145819 ENSG00000140443 ENSG00000087274 PMC3980263__F3 The LNG1 data set ENSG00000281324 ENSG00000291971 ENSG00000138798 ENSG00000113161 ENSG00000171791 ENSG00000166484 ENSG00000118777 ENSG00000149295 ENSG00000116161 ENSG00000112242 ENSG00000168772 ENSG00000132906 ENSG00000023445 ENSG00000087095 ENSG00000005339 ENSG00000100906 ENSG00000213341 ENSG00000131910 ENSG00000087460 ENSG00000007171 ENSG00000189283 ENSG00000145604 ENSG00000163904 ENSG00000174233 ENSG00000102312 ENSG00000119402 ENSG00000146648 PMC8898366__F9 PrPC Promotes Endometriosis Progression by Reprogramming Cholesterol Metabolism and Estrogen Biosynthesis of Endometrial Stromal Cells through PPARA Pathway ENSG00000113161 PMC3248195__F1 Elevated PI3K signaling drives multiple Breast Cancer subtypes ENSG00000109452 ENSG00000002330 ENSG00000169047 ENSG00000146678 ENSG00000140443 PMC4757520__F2 Signaling pathway alterations in Kupffer cells after alcohol and/or burn injury ENSG00000170458 ENSG00000136869 PMC9526616__F7 Early Development of Cardiac Fibrosis in Young Old-Father Offspring ENSG00000112837 ENSG00000118526 PMC4526690__F3 Comparison of the Transcriptional Profiles of Melanocytes from Dark and Light Skinned Individuals under Basal Conditions and Following Ultraviolet-B Irradiation PMC4017424__F1 NFKB signaling pathways ENSG00000168040 PMC3896749__F9 Hypothesis for the development of tactile allodynia following nerve injury ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC8490010__F3 From APC to the genetics of hereditary and familial colon cancer syndromes ENSG00000107779 ENSG00000121989 ENSG00000132781 ENSG00000134982 ENSG00000132646 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000095002 ENSG00000114739 ENSG00000122512 PMC8221416__F3 TLR signalling pathway ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000276561 ENSG00000164342 PMC8221416__F2 NLR signalling pathway ENSG00000167207 ENSG00000125538 ENSG00000177606 ENSG00000091592 ENSG00000106100 PMC4017424__F4 Activation of IKK pathway ENSG00000291971 ENSG00000198793 PMC5302996__F1 LncRNAs in pancreatic cancer ENSG00000135446 ENSG00000087586 ENSG00000143228 ENSG00000105810 ENSG00000130513 ENSG00000196363 PMC10473144__F3 Resveratrol Mediated Regulation of Hippocampal Neuroregenerative Plasticity via SIRT1 Pathway in Synergy with Wnt Signaling: Neurotherapeutic Implications to Mitigate Memory Loss in Alzheimer’s Disease ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC10473144__F2 Resveratrol Mediated Regulation of Hippocampal Neuroregenerative Plasticity via SIRT1 Pathway in Synergy with Wnt Signaling: Neurotherapeutic Implications to Mitigate Memory Loss in Alzheimer’s Disease ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8883733__F2 Mucor circinelloides: a model organism for oleaginous fungi and its potential applications in bioactive lipid production ENSG00000122966 ENSG00000172005 ENSG00000197429 PMC6240607__F4 Schematic depiction of GDNF/RET/GFRA1 signaling in the ureteric bud (UB) tip during kidney development ENSG00000164056 ENSG00000244405 ENSG00000175832 PMC9455009__F1 Programmed Necrosis in Colorectal Cancer ENSG00000102871 ENSG00000167468 ENSG00000145649 ENSG00000168040 ENSG00000127191 PMC11870059__F8 Metabolic pathway reconstruction graphs of the starch, nitrogen, and lipid in the rumen of sheep fed different forage and grain sources ENSG00000189060 ENSG00000124575 ENSG00000124610 ENSG00000184357 ENSG00000187837 PMC4271074__F8 OAA effects and inter-effect relationships ENSG00000198793 ENSG00000077279 ENSG00000106459 PMC10452754__F2 The molecular interaction between HLA-G and decidual NK cells at the maternal–fetal interface ENSG00000105894 ENSG00000005882 ENSG00000276051 PMC6830889__F1 Main TLR-mediated signaling pathways triggered upon stimulation by LPS and LPG ENSG00000174125 ENSG00000162711 ENSG00000167461 ENSG00000125538 ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC8932105__F7 Tumor-associated macrophage derived IL-6 enriches cancer stem cell population and promotes breast tumor progression via Stat-3 pathway ENSG00000168610 PMC9179504__F1 Small Extracellular Vesicles: Key Forces Mediating the Development and Metastasis of Colorectal Cancer ENSG00000163220 ENSG00000112699 ENSG00000168610 ENSG00000121966 PMC6527583__F4 Acute phase response network: The acute phase response was the most-significantly represented pathway common to all CAPN5-NIV stages ENSG00000180210 ENSG00000138207 ENSG00000113905 ENSG00000113600 ENSG00000203485 ENSG00000288512 ENSG00000244731 ENSG00000229314 ENSG00000171560 ENSG00000182326 ENSG00000236625 ENSG00000106927 PMC5711380__F7 Schematic summary of the IL-1B–IL-1 receptor signaling cascades identified in decidualizing human ESCs ENSG00000104856 ENSG00000109320 ENSG00000198793 PMC9489753__F2 Liver Regeneration in Chronic Liver Injuries: Basic and Clinical Applications Focusing on Macrophages and Natural Killer Cells ENSG00000154342 ENSG00000168329 ENSG00000108691 ENSG00000125538 ENSG00000112715 ENSG00000121807 ENSG00000168610 PMC9489753__F1 Liver Regeneration in Chronic Liver Injuries: Basic and Clinical Applications Focusing on Macrophages and Natural Killer Cells ENSG00000019991 ENSG00000140285 ENSG00000111321 ENSG00000102678 PMC7695717__F6 Oxytocin signalling network enriched in the analysis of the interaction of diet and n-3 PUFA supplementation in pregnant heifers ENSG00000105664 ENSG00000105656 ENSG00000254550 PMC4269339__F2 Signal transducer and activator of transcription 3 (STAT3) pathways involved in immune escape ENSG00000111537 ENSG00000115415 ENSG00000138798 ENSG00000232326 ENSG00000168610 ENSG00000146648 PMC6016836__F3 Herpesvirus-encoded microRNAs detected in human gingiva alter host cell transcriptome and regulate viral infection ENSG00000115091 ENSG00000172380 ENSG00000070831 ENSG00000163558 ENSG00000291971 ENSG00000113070 ENSG00000083457 ENSG00000149269 ENSG00000099942 ENSG00000146648 ENSG00000196570 PMC3272142__F4 Signaling pathways promoting trophoblast invasion and migration ENSG00000198793 ENSG00000163914 ENSG00000168036 PMC5794834__F1 Complement amplification loop ENSG00000274619 ENSG00000039537 ENSG00000113600 PMC7069124__F4 Overlaying the consensus TLR4 signaling pathway in databases with HemeKG (A: original overlaid network, B: overlaid network after inclusion of literature evidence for effectors) ENSG00000169248 ENSG00000104365 ENSG00000100906 ENSG00000269335 ENSG00000065559 ENSG00000213341 ENSG00000169032 ENSG00000150455 ENSG00000276561 ENSG00000169245 ENSG00000281614 ENSG00000170458 ENSG00000138755 ENSG00000125538 ENSG00000134070 ENSG00000169429 ENSG00000136869 ENSG00000157625 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000090376 ENSG00000171533 ENSG00000184216 PMC7069124__F3 Consensus around the TLR4 signaling pathway in three major pathway databases ENSG00000141639 ENSG00000136869 ENSG00000213341 ENSG00000150455 PMC5842404__F4 AMP‐dependent protein kinase (AMPK) signalling pathway ENSG00000148798 ENSG00000167419 PMC5842404__F3 B cell receptor (BCR) signalling pathway ENSG00000095585 ENSG00000067066 ENSG00000169896 ENSG00000151693 ENSG00000081051 ENSG00000010671 PMC8145847__F3 Hepatitis C Virus Uses Host Lipids to Its Own Advantage ENSG00000130164 ENSG00000110651 PMC8308767__F4 Phytomedicines Targeting Cancer Stem Cells: Therapeutic Opportunities and Prospects for Pharmaceutical Development ENSG00000168036 ENSG00000164690 ENSG00000128602 ENSG00000139687 PMC9165556__F1 Deleterious Genetic Variation Across the NOD Signaling Pathway Is Associated With Reduced NFKB Signaling Transcription and Upregulation of Alternative Inflammatory Transcripts in Pediatric Inflammatory Bowel Disease ENSG00000023445 ENSG00000162711 ENSG00000150782 ENSG00000110330 ENSG00000167207 ENSG00000103490 ENSG00000187796 ENSG00000078747 ENSG00000125538 ENSG00000154059 PMC3509712__F1 Signal transduction pathways used by superantigens and mediators ENSG00000213928 ENSG00000291603 ENSG00000213658 ENSG00000198793 ENSG00000163914 ENSG00000168040 ENSG00000125347 ENSG00000175104 PMC7961492__F1 Mechanisms and molecules involved in cholesterol metabolism and homeostasis and the regulatory effects of Non-encoding RNAs are depicted in a foam cell ENSG00000120437 PMC9683098__F6 ECM-associated protein secretion and intracellular accumulation in dermal fibroblasts PMC4177547__F1 PI3K/Akt/mTOR pathway and relative inhibitors in NHL ENSG00000198793 ENSG00000164327 PMC3403008__F3 Regulation of TLS in replication-associated ICL repair ENSG00000132646 ENSG00000070950 ENSG00000276787 PMC6584837__F1 PI3K/AKT and cell cycle signaling pathway model of NKTCL ENSG00000198793 ENSG00000164327 ENSG00000155629 PMC6527025__F7 Apoptosis Signalling in T-Helper Cells During HIV Infection.HIV proteins are involved in apoptosis ENSG00000120868 ENSG00000171791 ENSG00000121966 ENSG00000026103 PMC6527025__F6 UPR Signaling During Influenza A Virus Infection.Upon IAV infection, BiP is released from UPR proteins (e.g ENSG00000134109 ENSG00000128272 ENSG00000144895 ENSG00000088298 ENSG00000100219 PMC4546216__F5 Scheme of the phenylpropanoid pathway ENSG00000084774 PMC6527025__F5 Apoptosis Signaling During Influenza A Virus Infection.IAV infection affects apoptosis in early and late infection ENSG00000094631 ENSG00000002330 ENSG00000125538 ENSG00000108375 ENSG00000120885 PMC3528279__F3 RIG-I/MAVS signaling pathway regulating hMPV-induced NFKB and IRF activation in airway epithelial cells ENSG00000183735 ENSG00000088888 PMC3528279__F2 Toll-Like Receptors (TLR) signaling pathway involved in hMPV-induced gene expression in primary immune cells ENSG00000183735 ENSG00000170458 ENSG00000173039 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC7885587__F6 Pathway analysis ENSG00000162552 ENSG00000105329 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000112715 ENSG00000135341 ENSG00000125084 ENSG00000187134 ENSG00000106683 ENSG00000084676 ENSG00000082175 ENSG00000136997 ENSG00000146648 ENSG00000140443 ENSG00000172201 PMC6527025__F2 Apoptosis Signaling During Arbovirus Infection.Arboviruses exert their effect on apoptosis through different signaling routes ENSG00000002330 ENSG00000144895 ENSG00000102871 ENSG00000168040 ENSG00000135116 PMC6527025__F1 The roles of apoptosis, autophagy and unfolded protein response in arbovirus, influenza virus, and HIV infections ENSG00000088888 ENSG00000145782 ENSG00000057663 PMC3542934__F1 TGFB signalling pathway ENSG00000166147 PMC8927915__F1 Teaching cancer imaging in the era of precision medicine: Looking at the big picture ENSG00000134982 ENSG00000138798 ENSG00000146648 PMC6764500__F3 Significant metabolic pathways, Ubiquitin‐mediated proteolysis pathway and Adherens junction and Wnt signaling pathway for regulated genes associated with IS‐SM when compared to IS‐NSM ENSG00000012048 ENSG00000138795 ENSG00000132604 ENSG00000101871 ENSG00000169359 ENSG00000176928 ENSG00000288368 ENSG00000131480 ENSG00000115419 PMC4826512__F3 Targeting of the Wnt/Beta-catenin signaling pathway by Tat altered miRNAs ENSG00000087095 ENSG00000127445 ENSG00000137673 ENSG00000291971 ENSG00000168036 ENSG00000196628 PMC6689752__F1 Regulatory effects of micro-RNAs (miR) on specific stages of neuronal development ENSG00000106683 ENSG00000011304 PMC4826512__F4 Targeting of the axonal guidance signaling by Tat altered miRNA ENSG00000006607 ENSG00000182511 ENSG00000173156 ENSG00000010810 ENSG00000172602 ENSG00000169439 ENSG00000184661 ENSG00000121966 ENSG00000089159 PMC2679127__F2 PRRs and their corresponding ligands ENSG00000174123 ENSG00000174125 ENSG00000239732 ENSG00000167207 ENSG00000187554 ENSG00000172936 ENSG00000175104 ENSG00000164342 PMC7193471__F8 Signaling model of the IL6R-ADAR1-STAT3 interplay in multiple myeloma ENSG00000171791 ENSG00000168610 PMC9153132__F2 Intratumor microbiome in cancer progression: current developments, challenges and future trends ENSG00000181847 ENSG00000168036 ENSG00000078098 ENSG00000106546 PMC5357760__F2 Epidermal growth factor receptor (EGFR)–related signaling pathway in metastatic colorectal cancer ENSG00000198793 ENSG00000121879 ENSG00000146648 PMC9424811__F2 RING finger protein family in health and disease ENSG00000181852 ENSG00000034677 ENSG00000285152 ENSG00000265491 ENSG00000158717 ENSG00000120925 ENSG00000239732 ENSG00000124226 ENSG00000136869 ENSG00000137522 ENSG00000172936 ENSG00000131323 ENSG00000176641 ENSG00000175104 ENSG00000180537 ENSG00000133135 ENSG00000164342 PMC9548363__F8 Juniperus communis extract ameliorates lipopolysaccharide‐induced acute kidney injury through the adenosine monophosphate–activated protein kinase pathway ENSG00000108691 ENSG00000125538 ENSG00000136869 PMC9424811__F4 RING finger protein family in health and disease ENSG00000183735 ENSG00000164430 ENSG00000124226 ENSG00000265491 ENSG00000138942 ENSG00000157450 ENSG00000173456 ENSG00000133135 PMC7262792__F3 Possible mechanisms for growth hormone (GH) deficiency in children with mosaic gain-of-function mutations in the PI3K-AKT-MTOR pathway: ENSG00000291972 ENSG00000198793 ENSG00000140443 PMC9424811__F3 RING finger protein family in health and disease ENSG00000133874 ENSG00000123091 ENSG00000137275 ENSG00000265491 ENSG00000116514 ENSG00000101695 ENSG00000183735 ENSG00000088888 ENSG00000124226 ENSG00000164068 ENSG00000137522 ENSG00000131323 ENSG00000170633 ENSG00000133135 PMC8757826__F2 Oral Cancer Stem Cells: Therapeutic Implications and Challenges ENSG00000168283 ENSG00000138798 ENSG00000272398 ENSG00000026508 ENSG00000168036 ENSG00000128602 ENSG00000146648 PMC9424811__F5 RING finger protein family in health and disease ENSG00000173821 ENSG00000213928 ENSG00000163961 ENSG00000187608 ENSG00000105397 ENSG00000115415 ENSG00000121481 ENSG00000187147 ENSG00000285152 ENSG00000265491 ENSG00000116514 ENSG00000142166 PMC5579609__F3 PC-DHA levels depend on nutrition, liver and brain synthesis by PEMT and transport of LPC-DHA across the blood-brain barrier catalyzed by MFSD2A ENSG00000026103 ENSG00000116984 ENSG00000133027 PMC5974170__F3 Lipid droplets and the immune response during protozoan infection ENSG00000145321 ENSG00000237693 ENSG00000128915 PMC5090835__F1 Anesthesia-induced pathways of neuronal apoptosis.Anesthesia induces apoptosis by seven different pathways ENSG00000026103 PMC2948618__F3 3rd US-EU Workshop Systems level understanding of DNA damage responses ENSG00000149311 ENSG00000175054 ENSG00000101224 PMC2832236__F5 BS and M chloroplast distribution of proteins involved in primary carbon metabolism ENSG00000159224 ENSG00000197713 ENSG00000184207 ENSG00000169299 PMC7215321__F3 Necroptotic signaling pathway exemplified by tumor necrosis factor alpha (TNFA)-mediated activation of tumor necrosis factor receptor (TNFR)1 ENSG00000137275 ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC6142519__F3 Aberrations in the Ras signaling pathway that lead to excessive proliferation ENSG00000033327 ENSG00000110395 ENSG00000196712 PMC2830120__F3 Nicotinic Acetylcholine Receptor Signalling: Roles in Alzheimer's Disease and Amyloid Neuroprotection ENSG00000010810 ENSG00000168610 PMC5501852__F6 Interaction network of cancer cells and their microenvironment associated with the EMT process ENSG00000049323 ENSG00000019991 ENSG00000157404 ENSG00000130545 ENSG00000070831 ENSG00000105329 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000173482 ENSG00000100852 ENSG00000168036 ENSG00000104332 ENSG00000206075 ENSG00000049130 ENSG00000186340 ENSG00000122691 ENSG00000136869 ENSG00000164619 ENSG00000169903 ENSG00000137834 ENSG00000168610 ENSG00000197461 ENSG00000124216 ENSG00000163235 ENSG00000102981 ENSG00000177606 ENSG00000015285 ENSG00000164690 ENSG00000128602 ENSG00000146648 PMC3862457__F1 Signaling pathways that modulate amino acid, insulin/IGF-I, and resistance exercise–induced activation of mTORC1 signaling ENSG00000100150 ENSG00000114388 ENSG00000145979 ENSG00000085415 ENSG00000127580 ENSG00000167965 ENSG00000164654 ENSG00000103091 PMC7463266__F9 Illustration of this study’s results and a working model ENSG00000170365 ENSG00000168874 PMC9460414__F1 Plant-Derived (Poly)phenols and Their Metabolic Outcomes: The Pursuit of a Role for the Gut Microbiota ENSG00000105516 ENSG00000197971 PMC7377092__F1 ERK signaling ENSG00000012061 ENSG00000149311 ENSG00000175054 ENSG00000138798 PMC8374228__F3 Lymphadenopathy at the crossroad between immunodeficiency and autoinflammation: An intriguing challenge ENSG00000134982 ENSG00000173757 ENSG00000186716 ENSG00000198589 ENSG00000112182 ENSG00000168040 ENSG00000049768 ENSG00000168610 ENSG00000026103 PMC11937136__F6 Proposed mechanism for reproductive damage induced by ICIs through testicular inflammation, oxidative stress, and ferroptosis, as well as the protective role of RSV against ICIs-induced reproductive toxicity ENSG00000168003 ENSG00000151012 ENSG00000181019 ENSG00000167468 ENSG00000079999 PMC12140338__S1 Potential mechanism by which viridicatol (VDC), derived from deep‐sea fungus, enhances osteoblastogenesis through modulation of the Wnt/SHN3 signaling pathway ENSG00000029559 ENSG00000242252 ENSG00000134982 ENSG00000162551 ENSG00000291837 ENSG00000168036 PMC4314728__F9 Schematic of the signaling pathways activated by the P2Y2R in endothelial cells that are thought to regulate vascular permeability ENSG00000291507 ENSG00000160293 PMC4405894__F3 Pathway of all possible EGFR family dimer combinations showing various growth factors known to activate EGFR family and all possible dimer combinations ENSG00000065361 ENSG00000163235 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000168610 ENSG00000146648 ENSG00000178568 PMC5295437__F8 Growth factor progranulin promotes tumorigenesis of cervical cancer via PI3K/Akt/mTOR signaling pathway PMC5594916__F6 Schematic illustration shows targeting of the hnRNPA1/pri-miRNA-18*/K-RAS pathway by miR-25-3p and miR-15a-5p ENSG00000128191 ENSG00000113360 PMC4270387__F1 Examples of non-stress-related peroxide signaling ENSG00000138798 ENSG00000198670 ENSG00000105227 ENSG00000062485 PMC10669195__F1 Unleashing the Potential of Nrf2: A Novel Therapeutic Target for Pulmonary Vascular Remodeling ENSG00000178573 ENSG00000100387 ENSG00000113361 ENSG00000079999 PMC6682991__F1 Representation of the various selenium metabolic pathways leading to selenoprotein synthesis ENSG00000138018 ENSG00000183291 ENSG00000250722 ENSG00000178980 ENSG00000179918 ENSG00000176153 ENSG00000198832 ENSG00000211445 ENSG00000113811 ENSG00000198704 ENSG00000184470 ENSG00000167468 ENSG00000197763 ENSG00000211450 ENSG00000162430 ENSG00000186838 ENSG00000198843 ENSG00000073169 PMC2879321__F1 Signal transduction induced in endothelial cells by growth factor receptors involved in angiogenesis ENSG00000291971 ENSG00000172936 ENSG00000146648 ENSG00000174611 PMC11945442__F11 Proposed mechanism by which ACA affects the TNF-Alpha-induced NFKB pathway and ICAM-1 expression ENSG00000137275 ENSG00000102871 ENSG00000127191 PMC6494926__F1 Granulin biogenesis, quality control at the ribosome during its synthesis, and molecular mechanism of FTLD associated with mutations in the signal peptide of the granulin precursor ENSG00000003056 ENSG00000030582 ENSG00000197746 PMC6533287__F5 Human mTOR pathway ENSG00000106070 ENSG00000198793 ENSG00000163914 ENSG00000169047 ENSG00000145979 ENSG00000118515 ENSG00000155792 ENSG00000164327 PMC8568331__F2 Targeting cyclin-dependent kinase 4/6 as a therapeutic approach for mucosal melanoma ENSG00000157404 ENSG00000157764 ENSG00000168036 ENSG00000155903 ENSG00000146648 ENSG00000173327 ENSG00000139687 ENSG00000196712 PMC1781062__F1 CCM2 as a Scaffold for p38 MAPK Activation ENSG00000162889 ENSG00000065559 ENSG00000089022 PMC6104565__F5 Pharmacological targets of ErbB2 signaling pathway in Her2-enriched subtype ENSG00000169291 ENSG00000002330 ENSG00000110395 ENSG00000113070 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000136997 ENSG00000158458 ENSG00000169752 PMC4786834__F1 Linkage between the mechanisms of thrombocytopenia and thrombopoiesis ENSG00000151702 ENSG00000117400 ENSG00000105610 PMC4122595__F2 AB oligomers activate several ‘stress-response’ kinase pathways in neurons ENSG00000121351 ENSG00000198793 ENSG00000110931 PMC2784807__F5 Ingenuity Pathway Analysis® network depicting relationships among genes involved in immune and metabolic responses due to IMI with Streptococcus uberis ENSG00000135218 ENSG00000011422 ENSG00000170458 ENSG00000134324 ENSG00000099194 PMC10728021__F5 Proposed combination treatment strategy to tackle p53‐mutant esophageal squamous cell carcinoma (ESCC) tumors with a WEE1 inhibitor ENSG00000149311 ENSG00000175054 PMC2784807__F3 Cyclin-dependent kinase (CDK) 5 (A) and Insulin-like growth factor (IGF)-1 signaling pathways (B) among 2,102 differentially expressed genes due to intramammary infection with Streptococcus uberis ENSG00000175054 ENSG00000142192 ENSG00000108474 ENSG00000149269 ENSG00000140443 PMC2784807__F1 IL-10 and IL-6 signaling pathways among 2,102 DEG due to IMI with Streptococcus uberis ENSG00000169291 ENSG00000168610 ENSG00000026103 PMC9376115__F5 Regulated cell death (RCD) in cancer: key pathways and targeted therapies ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000091592 ENSG00000091106 ENSG00000147697 ENSG00000073605 PMC3260452__F2 Simplified model of the leptin signaling pathway ENSG00000173599 ENSG00000170893 ENSG00000124089 ENSG00000166603 PMC9376115__F6 Regulated cell death (RCD) in cancer: key pathways and targeted therapies ENSG00000163930 ENSG00000167468 ENSG00000111684 ENSG00000162772 ENSG00000127948 ENSG00000079999 PMC4251064__F2 Dataset was analyzed with the IPA software (Ingenuity Systems®, www.ingeuity.com) ENSG00000078900 ENSG00000169375 PMC4251064__F4 Canonical pathway of TP53 signaling: dataset was analyzed with the IPA software (Ingenuity Systems®, www.ingeuity.com) ENSG00000104499 ENSG00000175054 ENSG00000069188 ENSG00000112378 ENSG00000078237 ENSG00000140464 ENSG00000026103 ENSG00000198625 PMC12195631__F8 Regulatory mechanism of BB in the treatment of CAG ENSG00000170558 ENSG00000198793 PMC9376115__F3 Regulated cell death (RCD) in cancer: key pathways and targeted therapies ENSG00000177169 ENSG00000110497 ENSG00000123395 ENSG00000126775 ENSG00000144848 ENSG00000158828 ENSG00000168036 PMC9376115__F2 Regulated cell death (RCD) in cancer: key pathways and targeted therapies ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000168610 ENSG00000026103 PMC11275360__F6 Function and Mechanism of Long Noncoding RNAs in Adipogenic Differentiation ENSG00000198793 PMC5674931__F5 The role of metabolism and microRNA (miRNA) in daunorubicin and cytarabine treatment PMC11275360__F5 Function and Mechanism of Long Noncoding RNAs in Adipogenic Differentiation ENSG00000172680 ENSG00000159216 ENSG00000291971 PMC5674931__F4 The interactions between microRNAs (miRNAs) and cell death-related proteins in drug resistant cells ENSG00000171791 ENSG00000057663 ENSG00000026103 PMC11275360__F4 lncRNA regulates adipocyte differentiation through TGFB/BMPs/Smad signaling pathway ENSG00000135414 PMC11275360__F3 Function and Mechanism of Long Noncoding RNAs in Adipogenic Differentiation ENSG00000134982 ENSG00000168036 ENSG00000161202 PMC6929101__F3 TGFB activation in the tumor microenvironment ENSG00000178860 ENSG00000107562 PMC6929101__F2 TGFB alteration in colorectal cancer (CRC) cells ENSG00000111537 ENSG00000163739 ENSG00000163914 ENSG00000168036 ENSG00000112715 ENSG00000150630 PMC10483926__F7 Illustration of a hypothetical model in which TgESPs regulate aerobic glycolysis to promote osteogenic differentiation through the Wnt/Beta-catenin signaling pathway ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000159399 PMC6929101__F1 Schematic representation of Transforming growth factor-beta (TGFB) superfamily signaling pathway ENSG00000170365 ENSG00000163914 PMC5345933__F2A Cell cycle proteins as promising targets in cancer therapy ENSG00000228716 ENSG00000149311 ENSG00000039537 ENSG00000117525 ENSG00000135446 ENSG00000150907 ENSG00000136997 ENSG00000168036 ENSG00000123374 ENSG00000145386 ENSG00000105723 PMC4429713__F1 Radioactive 125I seeds inhibit cell growth and epithelial-mesenchymal transition in human glioblastoma multiforme via a ROS-mediated signaling pathway ENSG00000149311 ENSG00000175054 ENSG00000074266 PMC8068500__F2 Bioengineering strategies to control epithelial-to-mesenchymal transition for studies of cardiac development and disease ENSG00000168036 PMC8079716__F2 From purines to purinergic signalling: molecular functions and human diseases ENSG00000128050 PMC4258159__F5 The PI3K/mTOR signaling pathway upon stimulation with growth factors, with an emphasis on the phosphoregulation of PRAS40 ENSG00000169047 ENSG00000198793 ENSG00000155792 PMC5961053__F1 Production, elimination, and signaling of ROS ENSG00000105227 PMC9489683__F5 Maintaining the regulatory T cell program during inflammation: a delicate balance ENSG00000103266 ENSG00000187605 ENSG00000137033 ENSG00000165030 ENSG00000181847 ENSG00000125538 ENSG00000049768 ENSG00000136014 PMC9489683__F3 Treg suppression of conventional T cells ENSG00000089692 ENSG00000181847 ENSG00000134982 ENSG00000164120 ENSG00000168610 ENSG00000106546 ENSG00000026103 PMC9028246__F4 Genomic Hippo Pathway Alterations and Persistent YAP/TAZ Activation: New Hallmarks in Head and Neck Cancer ENSG00000126016 ENSG00000291971 ENSG00000163914 ENSG00000114978 ENSG00000146648 ENSG00000131023 ENSG00000173273 PMC4357373__F11 Identification of microRNAs and their target genes in Alport syndrome using deep sequencing of iPSCs samples ENSG00000196839 ENSG00000254550 PMC9028246__F2 Genomic Hippo Pathway Alterations and Persistent YAP/TAZ Activation: New Hallmarks in Head and Neck Cancer ENSG00000129474 ENSG00000113645 ENSG00000083857 ENSG00000126016 ENSG00000186575 ENSG00000160551 ENSG00000291971 ENSG00000163914 ENSG00000139926 ENSG00000114978 ENSG00000131023 PMC9028246__F1 Genomic Hippo Pathway Alterations and Persistent YAP/TAZ Activation: New Hallmarks in Head and Neck Cancer ENSG00000114978 ENSG00000131023 PMC11632667__F3 1) BMPs activates the SMAD pathway, which increases inflammatory cytokines VEGF, tumor necrosis factor alpha (TNFA), and Interleukin-6 (IL-6) ENSG00000178860 ENSG00000170365 ENSG00000137834 PMC7661081__F1 MRI Spectrum of Brain Involvement in Sphingosine-1-Phosphate Lyase Insufficiency Syndrome ENSG00000170989 ENSG00000180739 ENSG00000213694 ENSG00000125910 ENSG00000267534 PMC3901996__F2 Transmembrane signaling of IL-6, which is a major growth factor for MM ENSG00000115415 ENSG00000115904 ENSG00000168610 PMC8175905__F5 Intersecting Mechanisms of Hypoxia and Prostaglandin E2-Mediated Inflammation in the Comparative Biology of Oral Squamous Cell Carcinoma ENSG00000198793 ENSG00000168036 PMC3287579__F1 Adapted from ENSG00000173599 PMC9010499__F2 Intratumoral cancer immunotherapy exploiting anti-viral immunity ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC3730324__F1 HIFs are involved in crucial aspects of tumor progression and metastasis in sarcomas ENSG00000134086 PMC9641156__F3 Novel insight into the functions of N6-methyladenosine modified lncRNAs in cancers (Review) ENSG00000149658 ENSG00000173599 ENSG00000145321 ENSG00000165819 PMC11955304__F5 STAT3 signaling pathway can be targeted using various therapeutic agents ENSG00000091704 ENSG00000291971 ENSG00000168610 PMC11955304__F3 STAT3 Signaling Pathway in Health and Disease ENSG00000291971 ENSG00000168610 PMC5529905__F1 Signaling pathway resulting in TNFAlpha-mediated necroptosis, and specific necroptotic inhibitors targeting RIP1 and MLKL ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 PMC9028270__F2 Regulatory Processes of the Canonical Wnt/Beta-Catenin Pathway and Photobiomodulation in Diabetic Wound Repair ENSG00000134982 ENSG00000168036 PMC5670164__F2 Non-canonical activation of the sonic hedgehog (Shh) pathway ENSG00000164690 ENSG00000128602 PMC4341198__F8 Responses of Solid Tumor Cells in DMEM to Reactive Oxygen Species Generated by Non-Thermal Plasma and Chemically Induced ROS Systems ENSG00000188486 PMC5670164__F1 Sonic hedgehog (Shh) signaling pathway in a mammalian system ENSG00000164161 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC4041829__F1 Overview of cellular Na+ transport mechanisms and important components of the salt stress response network in plant root cells ENSG00000105722 ENSG00000100485 PMC4247580__F10 Arabidopsis Lipins, PDAT1 Acyltransferase, and SDP1 Triacylglycerol Lipase Synergistically Direct Fatty Acids toward Beta-Oxidation, Thereby Maintaining Membrane Lipid Homeostasis ENSG00000173599 ENSG00000026103 PMC8662819__F1 Single-Cell RNA Sequencing Reveals Multiple Pathways and the Tumor Microenvironment Could Lead to Chemotherapy Resistance in Cervical Cancer ENSG00000089692 ENSG00000188389 PMC5670164__F3 Regulation of thyroid cancer stem cell (CSC) self-renewal by the sonic hedgehog (Shh) pathway ENSG00000131914 ENSG00000168283 ENSG00000198793 ENSG00000184371 ENSG00000164690 ENSG00000128602 ENSG00000136826 PMC5822876__F6 Rheumatoid Arthritis-related molecular signaling pathway PMC3355898__F2 Somatic alterations in the PI3K pathway in prostate cancer ENSG00000109452 ENSG00000121879 PMC6476484__F1 Biological functions of IL-32 in inflammatory tumors ENSG00000087245 ENSG00000081041 ENSG00000137077 ENSG00000100985 PMC7769460__F6 The MAD2-TLR4-MyD88 axis in paclitaxel resistance in ovarian cancer ENSG00000237521 ENSG00000157404 ENSG00000112972 ENSG00000183287 ENSG00000058085 ENSG00000119888 ENSG00000109321 ENSG00000113070 ENSG00000186480 ENSG00000099194 ENSG00000117399 ENSG00000123219 ENSG00000187800 ENSG00000254550 ENSG00000128944 ENSG00000100290 ENSG00000011422 ENSG00000114126 ENSG00000135535 ENSG00000026508 ENSG00000136869 ENSG00000204217 PMC8467271__F3 Roles and Mechanisms of Deubiquitinases (DUBs) in Breast Cancer Progression and Targeted Drug Discovery ENSG00000135655 ENSG00000136535 ENSG00000165312 ENSG00000076604 PMC1773546__F3 The key proinflammatory pathway induced by enteric pathogens results in nuclear factor kappa B (NFKB) mediated transcription of interleukin 8 (IL-8) ENSG00000187554 ENSG00000172936 ENSG00000165527 ENSG00000175104 ENSG00000127191 PMC7794175__F1 Genomic alterations in the cyclin pathway in patients with cancer ENSG00000112576 ENSG00000135446 ENSG00000105810 ENSG00000118971 ENSG00000139687 ENSG00000124762 PMC3627353__F2 Genes and signaling pathways involved in ureteric budding ENSG00000103449 ENSG00000176692 ENSG00000145147 ENSG00000075891 ENSG00000107485 ENSG00000126778 ENSG00000185008 PMC8582360__F2 HGF/MET Signaling in Metastatic Uveal Melanoma ENSG00000019991 ENSG00000291971 ENSG00000198793 ENSG00000168610 PMC6533683__F10 Regulating EMT by targeting autophagy ENSG00000168036 ENSG00000189403 PMC2681266__F1 NFKB activation in cancer ENSG00000173039 ENSG00000146648 PMC6656421__F8 IPA Network ENSG00000171105 ENSG00000141448 ENSG00000138039 ENSG00000203859 ENSG00000111540 PMC4493903__F1 LIF is a new p53 negative regulator ENSG00000128342 ENSG00000168610 ENSG00000125968 PMC6640532__F1 Ubiquitin/26S proteasome system (UPS) ENSG00000100387 ENSG00000113558 ENSG00000291973 PMC7504089__F7 Differential gene expression in apoptosis and death receptor signaling pathway in ‘ECACC vs ENSG00000023445 ENSG00000125740 ENSG00000104365 ENSG00000142192 ENSG00000110330 ENSG00000002330 ENSG00000282905 ENSG00000137275 ENSG00000102871 ENSG00000269335 ENSG00000065559 ENSG00000213341 ENSG00000171791 ENSG00000168040 ENSG00000127191 ENSG00000111348 ENSG00000148935 ENSG00000115317 ENSG00000160049 ENSG00000178607 ENSG00000177606 ENSG00000120868 PMC3499997__F2 Main therapeutic targets along the BCR signaling pathway in CLL cells ENSG00000095585 ENSG00000186716 ENSG00000197943 ENSG00000010671 PMC3593794__F6 CDK5 phosphorylation substrates during neuronal migration ENSG00000166579 ENSG00000106683 ENSG00000077279 PMC9450390__F2 DNA damage repair (DDR) system in response to immune checkpoint inhibitor (ICI) therapy ENSG00000125347 ENSG00000168610 ENSG00000183735 ENSG00000111537 ENSG00000164430 ENSG00000088888 ENSG00000115415 ENSG00000138755 ENSG00000189403 ENSG00000169429 ENSG00000136869 ENSG00000172936 ENSG00000138385 PMC9450390__F1 DNA damage repair (DDR) system in response to immune checkpoint inhibitor (ICI) therapy ENSG00000145649 ENSG00000180644 ENSG00000138385 PMC3627353__F3 Genes and signaling pathways involved in ureter development ENSG00000121297 ENSG00000112837 ENSG00000157404 ENSG00000168036 ENSG00000263324 ENSG00000164690 ENSG00000128602 PMC9471952__F2 Neuregulin-1, a potential therapeutic target for cardiac repair ENSG00000162711 ENSG00000065361 ENSG00000109321 ENSG00000168036 ENSG00000146648 ENSG00000178568 PMC2603427__F5 Hierarchical layout of the EGFR1 pathway downloaded from the HPRD pathway database ENSG00000132906 ENSG00000291971 ENSG00000198561 ENSG00000168610 ENSG00000061938 ENSG00000107295 ENSG00000129219 ENSG00000188313 ENSG00000173757 ENSG00000067606 ENSG00000177606 ENSG00000136997 ENSG00000166501 ENSG00000124181 ENSG00000143333 PMC7199893__F4 FATE OF ALT-INHIBITED CANCER CELLS ENSG00000175054 ENSG00000149346 ENSG00000284238 ENSG00000198887 ENSG00000187790 ENSG00000180543 ENSG00000197299 ENSG00000140464 ENSG00000111247 PMC9546849__F3 RNA m6A writer WTAP in diseases: structure, roles, and mechanisms ENSG00000138798 ENSG00000146457 ENSG00000142166 PMC8599985__F2 Emerging Role of Non-Coding RNAs in Regulation of T-Lymphocyte Function ENSG00000118503 ENSG00000164400 ENSG00000136869 ENSG00000049768 ENSG00000168610 ENSG00000146648 PMC2603427__F6 Hierarchical layout of the B-cell receptor pathway downloaded from the HPRD pathway database ENSG00000108443 ENSG00000105647 ENSG00000010671 ENSG00000095585 ENSG00000180353 ENSG00000197943 ENSG00000123374 ENSG00000072135 ENSG00000105810 ENSG00000139687 ENSG00000184304 ENSG00000198286 ENSG00000132906 ENSG00000157764 ENSG00000007312 ENSG00000281877 ENSG00000160691 ENSG00000221823 ENSG00000110395 ENSG00000120899 ENSG00000135446 ENSG00000010810 ENSG00000155629 ENSG00000131196 ENSG00000135605 ENSG00000105723 PMC8599985__F1 Emerging Role of Non-Coding RNAs in Regulation of T-Lymphocyte Function ENSG00000163464 ENSG00000105397 ENSG00000291971 ENSG00000138798 ENSG00000169047 ENSG00000177606 ENSG00000136997 ENSG00000127528 ENSG00000099942 ENSG00000146648 ENSG00000168685 PMC6332659__F3 Tissue-specific gene regulatory network of the top KDs in psoriasis ENSG00000151500 ENSG00000241839 ENSG00000140463 ENSG00000136997 ENSG00000023445 ENSG00000139193 ENSG00000182578 ENSG00000213341 ENSG00000166278 ENSG00000110876 ENSG00000224320 ENSG00000110395 ENSG00000179344 ENSG00000197296 ENSG00000170458 ENSG00000118503 ENSG00000163938 ENSG00000173692 ENSG00000146648 ENSG00000002330 ENSG00000291603 ENSG00000102871 ENSG00000181104 ENSG00000110651 ENSG00000216490 ENSG00000112715 ENSG00000103811 ENSG00000150782 ENSG00000077150 ENSG00000168461 ENSG00000125538 ENSG00000276051 ENSG00000056558 ENSG00000122862 ENSG00000026103 ENSG00000039537 ENSG00000275385 ENSG00000100906 ENSG00000198851 ENSG00000162924 ENSG00000110324 ENSG00000231925 ENSG00000273936 ENSG00000215788 ENSG00000019582 ENSG00000065978 ENSG00000175416 ENSG00000117091 ENSG00000163131 ENSG00000164136 ENSG00000145649 PMC7068214__F7 Investigation of the Genome-Wide Genetic and Epigenetic Networks for Drug Discovery Based on Systems Biology Approaches in Colorectal Cancer ENSG00000162552 ENSG00000170190 ENSG00000176142 ENSG00000178078 ENSG00000114098 ENSG00000110799 ENSG00000102924 ENSG00000062096 ENSG00000113140 ENSG00000143401 ENSG00000167393 ENSG00000197063 ENSG00000106546 ENSG00000160193 ENSG00000001561 ENSG00000148175 ENSG00000152208 ENSG00000178732 ENSG00000101213 ENSG00000293532 PMC9546849__F6 Other functions of WTAP in cancers ENSG00000137673 ENSG00000134982 ENSG00000168036 ENSG00000271447 ENSG00000146457 ENSG00000146648 ENSG00000167434 PMC6826908__F1 Canonical Wnt signaling pathway ENSG00000134982 ENSG00000183579 ENSG00000108375 PMC2361115__F1 Cytoplasmic/traditional and nuclear modes of the EGFR signalling pathway ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC4847613__F6 Regulation of trophectoderm (TE) lineage specification by mevalonate pathway ENSG00000165556 ENSG00000163914 ENSG00000113161 ENSG00000197905 ENSG00000107485 PMC5458287__F1 Targeting HOX/PBX dimers in cancer ENSG00000162772 ENSG00000146648 ENSG00000064012 ENSG00000164305 PMC8801368__F1 Progesterone Receptors in Breast Cancer ENSG00000162552 ENSG00000107562 ENSG00000121966 PMC5356509__F2 Intrinsic and extrinsic apoptotic pathways, the TRADD/NFKB survival pathway, and the growth factor (GF) receptors PI3K/AKT pro-survival signaling axis in CSCs ENSG00000002330 ENSG00000102871 ENSG00000168040 PMC9225081__F2 Post-Translational Modifications of PCNA: Guiding for the Best DNA Damage Tolerance Choice ENSG00000132646 ENSG00000070950 ENSG00000051180 PMC6523766__F2 Metabolic reprogramming in RCC ENSG00000117118 ENSG00000115419 ENSG00000026103 PMC6523766__F1 Genetic mutations, HIF-1A activation and metabolism of RCC ENSG00000163235 ENSG00000105656 PMC7226520__F3 Adipocytokine signaling pathway in humans (KEGG hsa04920) ENSG00000102871 ENSG00000198793 ENSG00000127191 ENSG00000168610 PMC5486005__F1 Key miRNAs in the resistance to BC treatment ENSG00000198793 ENSG00000168610 PMC5831670__F4 Inhibition of Butyrylcholinesterase with Fluorobenzylcymserine, An Experimental Alzheimer’s Drug Candidate: Validation of Enzoinformatics Results by Classical and Innovative Enzyme Kinetic Analyses ENSG00000189403 PMC7226520__F7 Comparative downstream pathway analysis of the effect of the adipocytokine pathway in breast cancer using the SEanalysis web tool for super enhancer associated regulatory analysis ENSG00000179862 ENSG00000115648 ENSG00000111057 ENSG00000291560 ENSG00000179058 ENSG00000114019 ENSG00000124171 ENSG00000127129 ENSG00000076604 PMC5642638__F2 Role of PLZF as a tumor suppressor in prostate cancer ENSG00000157764 ENSG00000167749 ENSG00000138798 PMC7774091__F8 Proposed apoptotic pathway for the anticancer compound, SYA013 ENSG00000006712 ENSG00000171791 PMC6162242__F8 A schematic for an miR-532-5p/KRAS-NAP1L1/P-ERK/ETS1 feedback loop PMC9654658__F1 Transcriptomic Analysis in Human 3D Skin Model Injected with Resorbable Hyaluronic Acid Fillers Reveals Foreign Body Response ENSG00000111537 ENSG00000105329 ENSG00000121058 ENSG00000164136 ENSG00000277263 PMC8897182__F2 Interplay of Low-Density Lipoprotein Receptors, LRPs, and Lipoproteins in Pulmonary Hypertension ENSG00000130164 ENSG00000171759 ENSG00000204217 PMC6776600__F11 Complement inhibitors target different levels and steps of the complement cascade ENSG00000009724 PMC9654658__F3 Transcriptomic Analysis in Human 3D Skin Model Injected with Resorbable Hyaluronic Acid Fillers Reveals Foreign Body Response ENSG00000172680 ENSG00000198576 ENSG00000198363 ENSG00000026103 PMC8416576__F4 Repurposing new drug candidates and identifying crucial molecules underlying PCOS Pathogenesis Based On Bioinformatics Analysis ENSG00000138207 ENSG00000121410 ENSG00000105329 ENSG00000110244 ENSG00000138798 ENSG00000113140 ENSG00000112715 ENSG00000130175 ENSG00000122194 ENSG00000106927 PMC6250919__F1 Genetic polymorphisms more consistently associated with non-alcoholic fatty liver disease and their suggested physiopathological role ENSG00000213996 ENSG00000100344 ENSG00000084734 ENSG00000273592 PMC8416576__F5 Repurposing new drug candidates and identifying crucial molecules underlying PCOS Pathogenesis Based On Bioinformatics Analysis ENSG00000100519 ENSG00000100412 ENSG00000146701 ENSG00000089597 PMC8343402__F5 Impaired Lung Development and Ciliation in Mannosidase-1-Alpha-2 (Man1a2) Mutants ENSG00000123240 ENSG00000160551 ENSG00000178999 ENSG00000108641 ENSG00000173905 ENSG00000112118 ENSG00000101843 ENSG00000073111 ENSG00000162772 ENSG00000198056 ENSG00000076003 ENSG00000145020 ENSG00000230034 ENSG00000166508 ENSG00000213380 ENSG00000093009 ENSG00000134086 ENSG00000135720 ENSG00000168214 ENSG00000166685 ENSG00000150907 ENSG00000136997 ENSG00000204843 ENSG00000100219 ENSG00000144061 ENSG00000048342 ENSG00000078674 ENSG00000196712 ENSG00000148400 ENSG00000197102 ENSG00000167552 ENSG00000291348 ENSG00000205220 ENSG00000068971 ENSG00000109805 ENSG00000167468 ENSG00000164597 ENSG00000124440 ENSG00000096717 ENSG00000108587 ENSG00000108433 ENSG00000100196 ENSG00000000419 ENSG00000131446 ENSG00000134910 ENSG00000172269 ENSG00000136854 ENSG00000135823 ENSG00000117411 ENSG00000104833 ENSG00000166851 ENSG00000110801 ENSG00000072364 ENSG00000198162 ENSG00000196547 ENSG00000126803 ENSG00000177084 ENSG00000112893 ENSG00000119977 ENSG00000125814 ENSG00000109320 ENSG00000184445 ENSG00000163902 ENSG00000144791 ENSG00000105402 ENSG00000138160 ENSG00000291973 ENSG00000138674 ENSG00000185627 ENSG00000177606 ENSG00000167325 ENSG00000163527 ENSG00000171848 ENSG00000164690 ENSG00000149554 PMC4490948__F2 IRE1–RIDD–RIG-I pathway ENSG00000088888 ENSG00000100219 ENSG00000127191 PMC4357785__F6 Important pathways in HCC Shown is the mTOR/AKP/PIP3 pathway that contributes to transformation of nodules into metastatic counterparts ENSG00000002330 ENSG00000112964 ENSG00000148204 ENSG00000198793 ENSG00000163914 PMC9679411__F6 Delamanid suppresses CXCL10 expression via regulation of JAK/STAT1 signaling and correlates with reduced inflammation in tuberculosis patients ENSG00000169245 PMC5330314__F7 High-fat diet-induced complement activation mediates intestinal inflammation and neoplasia, independent of obesity ENSG00000125538 PMC3593794__F3 PAFAH1B1 (platelet-activating factor acetylhydrolase 1 regulatory subnuit 1, formerly known as LIS1)-binding partners ENSG00000166579 ENSG00000090273 ENSG00000007168 ENSG00000070831 ENSG00000140575 ENSG00000077279 ENSG00000173406 PMC6911354__F1 MYC as master regulator of proliferative lipid metabolic pathways: fatty acid synthesis, fatty acid elongation, and glycerophospholipid synthesis ENSG00000131473 ENSG00000163624 ENSG00000170522 ENSG00000136997 ENSG00000197977 ENSG00000169710 ENSG00000198670 ENSG00000099194 ENSG00000026103 PMC7076845__F7 Modulating NF-kappa B signaling pathway of DHI against UA ENSG00000102871 ENSG00000138798 ENSG00000099860 ENSG00000111321 ENSG00000150455 ENSG00000010671 ENSG00000095585 ENSG00000213658 ENSG00000186197 ENSG00000135960 ENSG00000082512 ENSG00000125538 ENSG00000056558 ENSG00000197943 ENSG00000242689 ENSG00000127191 ENSG00000149311 ENSG00000226275 ENSG00000170458 ENSG00000186716 ENSG00000172936 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000121060 PMC10584331__F2 Reverse of liver fibrosis by inducing ferroptosis by bioactivated compounds in HSCs ENSG00000163930 ENSG00000128016 ENSG00000105550 ENSG00000167468 PMC7216212__F3 Dichotomic Role of Macrophage Migration Inhibitory Factor in Neurodegeneration ENSG00000171720 ENSG00000131095 PMC10584331__F1 Ferroptosis mechanisms ENSG00000196839 ENSG00000167468 ENSG00000111684 PMC2835321__F6 Retrograde mechanisms in NMJ formation PMC3069769__F1 Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy ENSG00000169047 ENSG00000118515 ENSG00000155792 PMC7297083__F2 Interaction between pattern recognition receptors (PRRs) from dendritic cells (DCs) and VLPs PMC4398389__F1 Unraveling the Molecular Signatures of Oxidative Phosphorylation to Cope with the Nutritionally Changing Metabolic Capabilities of Liver and Muscle Tissues in Farmed Fish ENSG00000140740 ENSG00000073578 ENSG00000130414 ENSG00000131495 ENSG00000117118 ENSG00000116885 ENSG00000166136 ENSG00000147123 ENSG00000205138 ENSG00000139180 ENSG00000164405 ENSG00000184752 ENSG00000167985 ENSG00000160194 ENSG00000169021 ENSG00000185633 ENSG00000171953 ENSG00000147684 ENSG00000184983 ENSG00000179091 ENSG00000156467 ENSG00000292058 ENSG00000010256 ENSG00000165264 ENSG00000178127 ENSG00000143252 ENSG00000267855 ENSG00000183648 ENSG00000136521 ENSG00000127184 ENSG00000109390 ENSG00000213619 ENSG00000065518 ENSG00000151366 ENSG00000186010 ENSG00000189043 ENSG00000184076 ENSG00000099795 ENSG00000119013 PMC6937732__F8 Schematic model depicting the promotion of esophageal squamous cell carcinoma (ESCC) cell metastasis ENSG00000291971 ENSG00000168610 PMC4284611__F7 A model of enhanced cancer invasiveness and proliferation elicited by adjacent fibroblasts ENSG00000106025 ENSG00000168036 ENSG00000124875 PMC9315629__F5 Circular RNA in Brain Tumor Development ENSG00000117020 ENSG00000078747 ENSG00000026508 ENSG00000112715 ENSG00000109670 PMC7762545__F3 The conventional Kyoto Encyclopedia of Genes and (KEGG)-determined ccRCC pathway in the three cancer nodules with respect to the normal tissue from the right kidney ENSG00000134086 ENSG00000005339 ENSG00000100387 ENSG00000163235 ENSG00000112715 ENSG00000269858 PMC6332805__F3 Selective Autophagy degrades cell cycle proteins ENSG00000094631 ENSG00000103266 ENSG00000134086 ENSG00000123374 ENSG00000051180 ENSG00000149554 PMC6332805__F2 Different types of autophagy ENSG00000126775 ENSG00000145782 ENSG00000057663 PMC9315629__F4 Circular RNA in Brain Tumor Development ENSG00000087245 ENSG00000165480 ENSG00000110713 ENSG00000112715 ENSG00000198018 ENSG00000080298 ENSG00000093009 PMC9315629__F3 Circular RNA in Brain Tumor Development ENSG00000102699 ENSG00000124766 ENSG00000000971 ENSG00000100985 ENSG00000160410 ENSG00000188994 PMC6177508__F1 Schematic model for phosphorylation-dependent YAP translocation by DVL ENSG00000168036 ENSG00000150457 PMC6034857__F11 MAPK signaling pathway ENSG00000172680 ENSG00000170458 ENSG00000138798 ENSG00000177606 ENSG00000130159 ENSG00000127191 ENSG00000026103 PMC7886700__F1 Growth factor mediated activation of AKT1 PMC6034857__F10 Transcriptome study on Macrobrachium nipponense hepatopancreas experimentally challenged with white spot syndrome virus (WSSV) ENSG00000177455 ENSG00000103479 ENSG00000065833 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000169047 ENSG00000120885 PMC2590699__F1 Current model for Okazaki fragment maturation ENSG00000138346 ENSG00000140451 PMC3165799__F1 Schematic diagram of the ER stress response ENSG00000128272 ENSG00000144895 PMC9116919__F2 Vascular Calcification in Chronic Kidney Disease: An Update and Perspective ENSG00000152266 ENSG00000147162 ENSG00000125398 ENSG00000162337 ENSG00000120149 ENSG00000198793 ENSG00000168036 ENSG00000172936 ENSG00000136869 ENSG00000096717 ENSG00000168610 PMC11361845__F5 Analysis of changes in the proteome and phosphoproteome according to DNK72 treatment in patient derived glioblastoma cells ENSG00000069482 ENSG00000163914 PMC10378680__F5 The Piezo1 Mechanosensitive Channel in Heart Failure ENSG00000105329 ENSG00000125538 ENSG00000121807 ENSG00000103335 PMC3175149__F1 IL-33 release and signaling via ST2L ENSG00000137033 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC8835847__F8 microRNA-21 Regulates Stemness in Pancreatic Ductal Adenocarcinoma Cells ENSG00000272398 ENSG00000026508 ENSG00000168036 ENSG00000121966 PMC4863577__F1 Hh pathway critical components which could be targeted by potential antibasal cell carcinoma drugs.Notes: The mechanism of action of each single drug is explained in the text ENSG00000128602 ENSG00000146648 PMC8167111__F6 FGF2/MAST4/ERM pathway in SSC self-renewal ENSG00000107562 PMC7753217__F2 IFITM3’s mode of action in cancer ENSG00000115415 ENSG00000198793 ENSG00000168036 ENSG00000142089 ENSG00000168610 ENSG00000136826 PMC12025613__F1 Key pathways involved in hepatocellular carcinoma metastasis ENSG00000137834 ENSG00000106571 ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC6031408__F8 Schematic describing the proposed role of MYC and CDKN1A in Wnt/Beta-catenin (CTNNB1) and angiopoietin pathway-dependent hyaloid vessel regression ENSG00000281324 ENSG00000162337 ENSG00000188064 ENSG00000168036 ENSG00000124762 PMC3712086__F5 Diagram illustrating the signaling mechanism of how CARD9 may be inhibiting apoptosis from TNF-alpha ENSG00000187796 ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC5863305__F1 Role of miR-146a in diabetic microvascular complications ENSG00000148400 ENSG00000134070 ENSG00000175104 ENSG00000168610 ENSG00000184216 ENSG00000178568 PMC3069839__F5 Regulation of Atm pathway genes after Rif-Phen-MCT ENSG00000149311 ENSG00000012048 ENSG00000078900 ENSG00000177606 ENSG00000183765 PMC7142218__F1 FGF2 functions through FGFR dependent or independent pathways ENSG00000066468 ENSG00000088888 ENSG00000160867 ENSG00000077782 ENSG00000276561 PMC6345046__F5 Relationship between autophagy and cytokines ENSG00000198793 ENSG00000136869 ENSG00000175104 ENSG00000057663 ENSG00000164342 PMC3146511__F6 Expression and Functional Roles of Angiopoietin-2 in Skeletal Muscles ENSG00000065328 ENSG00000115163 ENSG00000277909 ENSG00000134982 ENSG00000138709 ENSG00000171848 ENSG00000143228 ENSG00000126787 ENSG00000138160 ENSG00000093009 PMC6814598__F1 Damaged nuclear DNA export, sensing and clearance in aging-related inflammation ENSG00000183735 ENSG00000164430 PMC8125157__F2 Cholinergic Modulation of Neuroinflammation: Focus on A7 Nicotinic Receptor ENSG00000168610 PMC6678477__F1 Rac1 activation is regulated by GEFs and GAP ENSG00000156299 ENSG00000115904 ENSG00000160293 PMC10380735__F1 Molecular Mechanisms of Neuroinflammation in Alzheimer’s Disease, the Consequence of Neural Cell Death ENSG00000102871 ENSG00000120868 ENSG00000168040 ENSG00000026103 PMC3380518__F1 IL-33 signalling pathways ENSG00000137033 ENSG00000172936 ENSG00000185187 ENSG00000184216 PMC7349525__F3 PD-related proteins and chaperones involved in proteostasis: Other well-characterized PD-related proteins, their cellular localization and functional pathways involved are depicted in this figure ENSG00000105401 ENSG00000158828 ENSG00000112208 ENSG00000069329 ENSG00000116675 PMC9170603__F3 MicroRNAs and JAK/STAT3 signaling: A new promising therapeutic axis in blood cancers ENSG00000145839 ENSG00000291971 ENSG00000197272 ENSG00000168610 PMC9570382__F1 Non-Coding RNA Related to MAPK Signaling Pathway in Liver Cancer ENSG00000102678 PMC9570382__F3 Non-Coding RNA Related to MAPK Signaling Pathway in Liver Cancer ENSG00000214194 PMC9570382__F2 Non-Coding RNA Related to MAPK Signaling Pathway in Liver Cancer ENSG00000169967 ENSG00000142627 PMC9292941__F3 Genome of a nonphotosynthetic diatom provides insights into the metabolic shift to heterotrophy and constraints on the loss of photosynthesis ENSG00000173599 ENSG00000062485 PMC7058049__F9 Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation ENSG00000118503 PMC3980848__F1 MicroRNA Regulation of T Helper Cell Differentiation and Plasticity ENSG00000100385 ENSG00000111537 ENSG00000138166 ENSG00000150907 ENSG00000198793 ENSG00000167074 ENSG00000175104 ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC11539687__F2 This figure illustrates the neuroprotective mechanisms of GLP-1 receptor agonists (GLP-1RAs) in neurons and microglia, highlighting the key molecular pathways involved in neurodegeneration and inflammation ENSG00000162711 ENSG00000198793 PMC9457923__F1 ABCC4 inhibition as a potential therapeutic strategy against SHH-MB ENSG00000164690 ENSG00000128602 PMC3980848__F3 MicroRNA Regulation of T Helper Cell Differentiation and Plasticity ENSG00000115415 ENSG00000196498 ENSG00000049768 ENSG00000113360 PMC7861947__F6 Probable mechanisms of apigenin against liver fibrosis ENSG00000087245 ENSG00000163235 PMC4836414__F1 The butanone biosynthetic pathway ENSG00000261701 ENSG00000166278 ENSG00000150787 PMC6694253__F3 Sub-network of SNHG12 ENSG00000124102 ENSG00000073584 ENSG00000002330 ENSG00000168743 ENSG00000197471 ENSG00000198793 ENSG00000171791 ENSG00000166851 ENSG00000182459 ENSG00000247596 ENSG00000177455 ENSG00000162437 ENSG00000137807 ENSG00000103479 ENSG00000160193 ENSG00000146054 ENSG00000186716 ENSG00000276051 ENSG00000079950 ENSG00000139372 ENSG00000174197 ENSG00000196639 PMC8446364__F1 She Doesn’t Even Go Here: The Role of Inflammatory Astrocytes in CNS Disorders ENSG00000169245 ENSG00000115008 ENSG00000108691 ENSG00000125538 ENSG00000198793 ENSG00000131095 ENSG00000197063 PMC6826838__F7 Complement and coagulation cascades signaling pathway and RT-qPCR verification ENSG00000003436 ENSG00000140678 ENSG00000113600 ENSG00000110799 ENSG00000088926 ENSG00000166278 ENSG00000117322 ENSG00000152430 ENSG00000126218 ENSG00000173599 ENSG00000080618 ENSG00000198734 ENSG00000062485 PMC9265562__F3 Endothelial Autophagy in Coronary Microvascular Dysfunction and Cardiovascular Disease ENSG00000123240 ENSG00000099968 ENSG00000158828 ENSG00000069509 PMC7279331__F3 Calmodulin and protein kinase C (PKC) modulating critical features of KRas-driven tumourigenesis ENSG00000171791 PMC7279331__F2 Key signalling events modulated by Ca2+/calmodulin and decisive for cell proliferation and survival ENSG00000113070 ENSG00000146648 PMC4916957__F2 IDO in the Tumor Microenvironment: Inflammation, Counter-regulation and Tolerance PMC3888876__F2 MONOGENIC AUTOINFLAMMATORY DISEASES: DISORDERS OF AMPLIFIED DANGER SENSING AND CYTOKINE DYSREGULATION ENSG00000141527 ENSG00000162711 ENSG00000105397 PMC7056705__F2 Major mechanisms underlying induction of the host immune response by VPM1002 and M ENSG00000164430 ENSG00000163568 ENSG00000125538 PMC11726887__F10 Effect of echinacoside in HepG2 cells ENSG00000168003 ENSG00000151012 ENSG00000167468 PMC9570382__F4 Non-Coding RNA Related to MAPK Signaling Pathway in Liver Cancer ENSG00000135446 ENSG00000105810 ENSG00000146648 PMC3534598__F1 Cartoon depicting the role of sialidases during the multistep process of myogenesis ENSG00000162139 ENSG00000115488 ENSG00000146648 PMC6756057__F2 Schematic overview of genetic and epigenetic abnormalities in Wnt pathway components in MM and drugs that target canonical Wnt signaling ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000136997 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000087586 ENSG00000083799 PMC2748802__F18 Hypothesized descending pathway for translating emotional states or appetitive need for food, salt or water into goal-directed motor tasks ENSG00000090402 ENSG00000198576 PMC3323190__F7 Summary of the effects of leptin in the hypothalamus of control (A) and ob/ob mice (B), as revealed by Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) and 13C High-Resolution-Magic Angle Spinning (HR-MAS) ENSG00000198576 PMC8656934__F2 Targeting Metabolism to Control Immune Responses in Cancer and Improve Checkpoint Blockade Immunotherapy ENSG00000135218 ENSG00000134982 ENSG00000198793 ENSG00000136997 ENSG00000049768 ENSG00000159399 ENSG00000026103 PMC8307196__F7 Silibinin Regulates Tumor Progression and Tumorsphere Formation by Suppressing PD-L1 Expression in Non-Small Cell Lung Cancer (NSCLC) Cells ENSG00000173757 ENSG00000138798 ENSG00000146648 PMC4376961__F3 Schematic overview of autophagy machinery and its regulation by sphingolipids ENSG00000177169 ENSG00000123395 ENSG00000126775 ENSG00000144848 PMC8656934__F3 Targeting Metabolism to Control Immune Responses in Cancer and Improve Checkpoint Blockade Immunotherapy ENSG00000135218 ENSG00000118520 ENSG00000159399 ENSG00000026103 PMC4376961__F2 Key events in the apoptotic pathway and regulation of apoptosis by sphingolipids ENSG00000002330 ENSG00000171791 ENSG00000168040 ENSG00000104081 PMC5518849__F1 An overview of one-carbon metabolism and the established/future therapeutics that target this pathway ENSG00000228716 ENSG00000100714 ENSG00000092621 PMC9358979__F1 Mitochondrial impairment and repair in the pathogenesis of systemic lupus erythematosus ENSG00000162711 ENSG00000164430 ENSG00000125538 ENSG00000158828 PMC3609811__F1 Gene Expression Profile of the Hippocampus of Rats Subjected to Chronic Immobilization Stress ENSG00000136457 ENSG00000135218 ENSG00000168743 ENSG00000110799 ENSG00000162512 ENSG00000291748 ENSG00000115221 ENSG00000026508 ENSG00000115232 PMC3367552__F6 Interaction map showing potential links between the Par proteins and components of the Hippo pathway ENSG00000163914 ENSG00000168036 ENSG00000072415 PMC5892236__F1 Resveratrol inhibits the mTOR signaling pathway in the repair of SCI ENSG00000169047 ENSG00000198793 ENSG00000164327 PMC3609811__F2 Gene Expression Profile of the Hippocampus of Rats Subjected to Chronic Immobilization Stress ENSG00000110944 ENSG00000102962 ENSG00000138798 ENSG00000139269 ENSG00000164399 ENSG00000274736 ENSG00000103522 ENSG00000064300 ENSG00000121966 ENSG00000122025 ENSG00000131142 ENSG00000145623 ENSG00000135960 ENSG00000117400 ENSG00000128052 ENSG00000277236 ENSG00000147896 ENSG00000113520 ENSG00000164400 ENSG00000037280 ENSG00000128342 ENSG00000006606 ENSG00000162892 ENSG00000026103 ENSG00000143185 ENSG00000099985 ENSG00000242689 ENSG00000147168 ENSG00000108342 ENSG00000145777 ENSG00000226275 ENSG00000108691 ENSG00000145839 ENSG00000137077 ENSG00000146648 ENSG00000204217 ENSG00000115009 PMC8215697__F1 Developing Clostridia as Cell Factories for Short- and Medium-Chain Ester Production ENSG00000291368 PMC5396623__F4 SPARC overexpression alters microRNA expression profiles involved in tumor progression ENSG00000125571 ENSG00000109861 ENSG00000156103 ENSG00000163221 ENSG00000136696 ENSG00000136694 ENSG00000136695 ENSG00000168610 ENSG00000136688 PMC8748963__F9 NLK/SRF/ELK Pathway ENSG00000087095 ENSG00000163914 PMC6627638__F10 Epigenetic regulation of survivin in transformed cells ENSG00000173120 ENSG00000066135 PMC8626591__F1 Combined treatment of non‐small cell lung cancer using radiotherapy and immunotherapy: challenges and updates ENSG00000089041 ENSG00000189403 PMC6716297__F7 SUCO related genes involved in the cell cycle pathway ENSG00000118007 ENSG00000108055 ENSG00000205250 ENSG00000277273 ENSG00000117399 ENSG00000276876 ENSG00000093009 ENSG00000145604 ENSG00000094804 ENSG00000132646 ENSG00000135336 ENSG00000123374 ENSG00000164754 PMC11837758__F1 The metabolic pathway for the biosynthesis of monocyclic aromatic chemicals ENSG00000197487 ENSG00000150787 ENSG00000047597 ENSG00000158125 ENSG00000198947 PMC6678865__F4 Altered metabolism as the source of nadph biosynthesis ENSG00000125166 ENSG00000065833 ENSG00000135069 ENSG00000112992 ENSG00000146733 PMC3282946__F4 miR-23b and tretinoin, which was associated with this miRNA in thyroid cancer, shared the common target genes, ALDH1A1 and ALDH1A2 ENSG00000157764 ENSG00000170458 ENSG00000198793 ENSG00000119912 ENSG00000127191 ENSG00000026103 PMC6832683__F10 Schematic diagram illustrating the distinct roles of Nrp2 in corticostriatal pathway development, maintenance, and function ENSG00000197471 ENSG00000118257 PMC1885811__F4 Web-accessible pathway navigator ENSG00000102871 ENSG00000107201 ENSG00000150455 ENSG00000175104 PMC10179549__F10 HMGB2 in the development of the diseases ENSG00000087245 ENSG00000164430 ENSG00000145321 ENSG00000168036 ENSG00000164104 PMC7473503__F2 Androgen receptor pathway inhibitors and their mechanism of action PMC6770608__F10 Diallyl trisulfide (DATS) protected the brain tissue against the damage induced by ischemia/reperfusion (IR) ENSG00000100387 ENSG00000079999 PMC7412691__F6 Schematic diagram of the mechanism underlies miR‐155 function in chondrocyte apoptosis and catabolic activity ENSG00000149968 ENSG00000125538 PMC10926087__F1 Activated hedgehog gene pattern correlates with dismal clinical outcome and tumor microenvironment heterogeneity in hepatocellular carcinoma ENSG00000143147 ENSG00000064309 ENSG00000140323 ENSG00000106571 ENSG00000173040 ENSG00000144857 ENSG00000166813 ENSG00000128602 PMC1852964__F2 APC-Beta-catenin-Tcf (Wingless-Wnt signaling) pathway ENSG00000134982 ENSG00000168036 PMC3965671__F6 Mechanisms by which Th17 and Th22 pathways contribute to psoriasis and atopic dermatitis ENSG00000081041 ENSG00000163739 ENSG00000125538 ENSG00000108700 ENSG00000145321 ENSG00000169429 ENSG00000006606 ENSG00000166090 ENSG00000115009 ENSG00000106178 ENSG00000106546 PMC8096904__F5 Control Analysis of Protein-Protein Interaction Network Reveals Potential Regulatory Targets for MYCN ENSG00000121989 ENSG00000281178 ENSG00000121879 ENSG00000066468 ENSG00000070444 ENSG00000136997 ENSG00000123933 ENSG00000174197 ENSG00000108788 ENSG00000116990 ENSG00000135503 ENSG00000213347 ENSG00000077782 ENSG00000146648 ENSG00000140443 PMC4666791__F1 Schematic diagram shows major signaling pathways stimulated by IFNA/B (mediated by the type I IFN receptor) and viral pathogen-associated molecular patterns (PAMPs) and/or ICs-containing nucleic acids (mediated by endosomal TLRs) ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000177606 ENSG00000172005 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000168610 ENSG00000276561 ENSG00000142166 PMC3965671__F5 The Th17 Pathway and Inflammatory Diseases of the Intestines, Lungs and Skin ENSG00000081041 ENSG00000163739 ENSG00000108688 ENSG00000145321 ENSG00000169429 ENSG00000006606 ENSG00000166090 ENSG00000115009 ENSG00000106178 ENSG00000106546 PMC3965671__F4 Immunopathogenesis of inflammatory bowel disease (IBD) ENSG00000081041 ENSG00000167207 ENSG00000096395 ENSG00000137033 ENSG00000163739 ENSG00000125538 ENSG00000145321 ENSG00000169429 ENSG00000115009 PMC8579729__F1 Complement in ischaemia–reperfusion injury and transplantation ENSG00000009724 ENSG00000291559 ENSG00000062485 PMC7923337__F8 Overexpressed WDR3 induces the activation of Hippo pathway by interacting with GATA4 in pancreatic cancer ENSG00000285109 PMC9619106__F7 Transcriptome analysis reveals the proline metabolic pathway and its potential regulation TF-hub genes in salt-stressed potato ENSG00000250799 ENSG00000100033 PMC8436174__F1 HER2-Directed Therapy in Advanced Gastric and Gastroesophageal Adenocarcinoma: Triumphs and Troubles ENSG00000198793 ENSG00000146648 PMC8494520__F2 Immunology and Immune Checkpoint Inhibition in Ovarian Cancer – Current Aspects ENSG00000169245 ENSG00000164430 PMC4508762__F3 Transcripts regulating the Wnt signaling pathway are putatively affected by up-regulated miRNAs expression in the PCOS patients when compared with control ENSG00000087095 ENSG00000100592 ENSG00000100387 ENSG00000134982 ENSG00000147869 ENSG00000113558 ENSG00000148175 ENSG00000196470 PMC3185234__F1 Enterohepatic circulation of the bile ENSG00000138075 ENSG00000167910 ENSG00000143921 PMC6727741__F8 WDR92 in the axonemal dynein assembly pathway ENSG00000005175 ENSG00000104872 ENSG00000150773 ENSG00000121058 ENSG00000104450 ENSG00000165506 ENSG00000175792 PMC5166530__F2 CTHRC1 in multi-signaling pathways ENSG00000154342 ENSG00000164932 ENSG00000170365 ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000172269 ENSG00000168036 ENSG00000100985 ENSG00000125084 PMC6986204__F2 Molecular mechanism(s) regulating human Beta-cell proliferation ENSG00000157540 ENSG00000169047 ENSG00000140443 PMC4163633__F1 Innate recognition of HCV RNA ENSG00000183735 ENSG00000088888 ENSG00000187608 ENSG00000102871 ENSG00000082512 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000164342 PMC7589980__F1 Susceptibility genes present in the double-strand DNA break repair pathway for ovarian and breast cancer and its different correspondent risks levels in each disease ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000136492 ENSG00000083093 ENSG00000185379 ENSG00000104320 ENSG00000108384 ENSG00000149554 ENSG00000139618 ENSG00000183765 PMC4485443__F1 Structural determinants of SMAD function in TGFB signaling ENSG00000170365 ENSG00000137834 PMC8387325__F2 Recent findings within the C. elegans neuro-gut axis ENSG00000118515 PMC2953617__F2 JS genes implicated in the Shh, Wnt, and PDGFA signaling pathway ENSG00000169379 ENSG00000148384 ENSG00000164690 ENSG00000078674 PMC3632658__F1 Interplay between viruses and host mRNA degradation ENSG00000236826 ENSG00000170860 ENSG00000130332 ENSG00000111341 ENSG00000130520 ENSG00000164167 ENSG00000114127 ENSG00000135828 ENSG00000172795 PMC2886162__F5 SIRT1-dependent Regulation of Chromatin and Transcription: Linking NAD+ Metabolism and Signaling to the Control of Cellular Functions ENSG00000105835 ENSG00000132464 ENSG00000173614 ENSG00000096717 PMC2810404__F6 Hepatocyte expression of Serum Response Factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in mice ENSG00000086696 ENSG00000065328 ENSG00000112964 ENSG00000134057 ENSG00000131747 ENSG00000203859 ENSG00000051180 ENSG00000073111 ENSG00000146648 ENSG00000117399 PMC4257614__F4 Accounting for eXentricities: Analysis of the X Chromosome in GWAS Reveals X-Linked Genes Implicated in Autoimmune Diseases ENSG00000121310 ENSG00000142192 ENSG00000115163 ENSG00000125651 ENSG00000187790 ENSG00000196591 ENSG00000174804 ENSG00000183690 ENSG00000061938 ENSG00000143537 ENSG00000120063 ENSG00000198853 ENSG00000123496 ENSG00000062725 ENSG00000126247 ENSG00000128408 ENSG00000186675 ENSG00000224902 ENSG00000164107 ENSG00000215274 ENSG00000188677 ENSG00000170340 PMC2693450__F3 Lipodystrophies: Disorders of adipose tissue biology ENSG00000042832 ENSG00000158825 ENSG00000198670 PMC7185127__F2 Regulatory mechanism of mitochondrial quality control ENSG00000168958 ENSG00000069509 ENSG00000171109 ENSG00000214253 PMC3356061__F2 Molecular pathway of activation of autophagy ENSG00000177169 ENSG00000110497 ENSG00000123395 ENSG00000198382 ENSG00000198793 PMC7738881__F8 Schematic model depicting how 14-3-3σ performs anoikis resistance effects in HCC ENSG00000138798 ENSG00000146648 ENSG00000164305 PMC3840213__F8 Graphic summary of factors regulating Beta-cell proliferation and size as a function of pancreas developmental stages ENSG00000113494 PMC6163343__F1 HH-GLI signaling pathway ENSG00000143147 ENSG00000180447 ENSG00000106571 ENSG00000173040 ENSG00000164161 ENSG00000144857 ENSG00000171791 ENSG00000128602 PMC8610101__F1 Complement Pathways ENSG00000113600 ENSG00000244731 ENSG00000166278 ENSG00000236625 PMC4420620__F2 Novel functions of viral anti-apoptotic factors ENSG00000105397 ENSG00000137265 ENSG00000276561 PMC4420620__F1 Novel functions of viral anti-apoptotic factors ENSG00000198382 ENSG00000144848 PMC5086033__F1 Microenvironmental Regulation of Hematopoietic Stem Cells and Its Implications in Leukemogenesis ENSG00000178860 ENSG00000107562 ENSG00000163629 ENSG00000170558 ENSG00000168036 PMC8533566__F7 SOD3 Levels Is Detrimental to Retinal Homeostasis ENSG00000091664 ENSG00000109113 ENSG00000168818 PMC4087507__F1 NOD2/TLR4 signaling pathway ENSG00000167207 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC7356051__F1 Mammalian Arg/N-degron pathway ENSG00000156795 ENSG00000157045 ENSG00000127481 ENSG00000104517 ENSG00000159459 ENSG00000107669 PMC3141878__F1 TLR4 signaling cascade and evidence for modulation by neuropathic pain and opioids ENSG00000170458 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000150455 PMC2864389__F1 PI3K/AKT signaling pathway ENSG00000124102 ENSG00000002330 ENSG00000184481 PMC6265572__F6 MiRNA regulation in fetal cardiomyocytes, cardiac maturation and the risk of heart disease in adults ENSG00000134982 ENSG00000168036 ENSG00000150457 ENSG00000131023 ENSG00000140443 PMC4069271__F1A Hypoxia-Inducible Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) (HIF-1B): Is It a Rare Exception? ENSG00000134086 ENSG00000106546 PMC9168372__F2 Anti-Inflammatory Activities of Betulinic Acid: A Review ENSG00000162692 PMC6322862__F1 Schematic diagram of a simplified model for glucose-mediated mitochondrial transport regulation ENSG00000147162 ENSG00000291507 ENSG00000198408 PMC7897195__F4 SFRP2 overexpression in tumor endothelium leads to enhanced tumor angiogenesis via the Wnt/Ca2+signaling pathway ENSG00000163251 ENSG00000135605 PMC7897195__F2 SFRP2 and the canonical Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4861365__F1 The Fanconi anemia/BRCA repair pathway ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000144554 ENSG00000162607 ENSG00000051180 ENSG00000139618 PMC7057837__F1 Role of RUNX Family Transcription Factors in DNA Damage Response ENSG00000149311 ENSG00000175054 ENSG00000144554 ENSG00000116717 ENSG00000124762 PMC9251345__F5 Review of the Potential Effects of Melatonin in Compromised Mitochondrial Redox Activities in Elderly Patients With COVID-19 ENSG00000110711 ENSG00000139133 ENSG00000158828 ENSG00000172339 ENSG00000120868 ENSG00000182858 ENSG00000057663 ENSG00000115317 ENSG00000214253 PMC8039963__F7 Genetic and molecular signal dynamics that ZEN mainly affected during PF assembly ENSG00000162552 ENSG00000015285 ENSG00000125968 ENSG00000074219 PMC2556568__F2 Molecular processes that handle — and mishandle — dietary lipids ENSG00000138075 ENSG00000152700 ENSG00000042832 ENSG00000111701 ENSG00000015520 ENSG00000173599 ENSG00000120437 ENSG00000062282 ENSG00000143921 PMC7057837__F3 Role of RUNX Family Transcription Factors in DNA Damage Response ENSG00000143799 ENSG00000175054 ENSG00000159216 ENSG00000144554 ENSG00000020633 ENSG00000197299 PMC5847265__F1 Pediatric Pharmacogenomics: A systematic assessment of ontogeny and genetic variation to guide the design of statin studies in children ENSG00000057252 ENSG00000138075 ENSG00000130208 ENSG00000073060 ENSG00000130164 ENSG00000110244 ENSG00000167910 ENSG00000113161 ENSG00000100979 ENSG00000104549 ENSG00000143921 PMC4436943__F1 Wnt/Beta-catenin signalling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5078078__F6 NLRX1 suppresses tumorigenesis and attenuates histiocytic sarcoma through the negative regulation of NF-λB signaling ENSG00000104856 ENSG00000291603 ENSG00000125735 ENSG00000198793 ENSG00000095015 ENSG00000120889 ENSG00000111321 ENSG00000183735 ENSG00000077150 ENSG00000263528 ENSG00000164400 ENSG00000100065 ENSG00000198286 ENSG00000139193 ENSG00000104365 ENSG00000189056 ENSG00000269335 ENSG00000108342 ENSG00000168040 ENSG00000106100 ENSG00000226275 ENSG00000111537 ENSG00000177606 ENSG00000184371 ENSG00000131323 ENSG00000175104 ENSG00000146648 ENSG00000028137 ENSG00000184216 PMC10526378__F3 Angiogenesis in Lung Cancer: Understanding the Roles of Growth Factors ENSG00000168610 PMC10526378__F1 Angiogenesis in Lung Cancer: Understanding the Roles of Growth Factors ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC9099213__F1 “Self-Sacrifice” of ImmuneCells in Sepsis ENSG00000278718 ENSG00000091106 PMC2888584__F7 Endothelin-1 Inhibits Prolyl Hydroxylase Domain 2 to Activate Hypoxia-Inducible Factor-1A in Melanoma Cells ENSG00000198793 ENSG00000112715 PMC7802795__F13 Possible mechanism of anticancer activity of SnO2-ZnO/rGO NCs ENSG00000214285 ENSG00000164305 PMC11275100__F1 PARPi effect in cancer cells and immune cells ENSG00000012048 ENSG00000164430 ENSG00000139618 PMC3496044__F7 Sialic acid biosynthetic and degradative pathways ENSG00000159921 ENSG00000170191 ENSG00000111726 PMC5823602__F4 UBASH3B promotes tamoxifen resistance and could be negatively regulated by ESR1 ENSG00000154127 PMC5023837__F2 Ingenuity Pathways Analysis of the identified methylated targets ENSG00000154305 ENSG00000149968 ENSG00000148826 ENSG00000168036 ENSG00000173641 PMC1487177__F7 AKT-1/PKB Signaling ENSG00000171105 PMC5329888__F3 Sex determination within individual XY supporting cells depends on the level of Sox9 expression.A ENSG00000169218 ENSG00000125398 ENSG00000168036 ENSG00000102678 PMC10529750__F6 Oxidative Stress in Multiple Exercise-Regulated Bone Homeostasis ENSG00000172938 ENSG00000142082 PMC7854989__F2 Novel insights provided by single cell transcriptomics regarding hepatocytes and hepatic NPCs in nomal liver and during various injuries and pathological conditions ENSG00000197956 ENSG00000135218 ENSG00000143546 ENSG00000118785 ENSG00000163220 ENSG00000125538 ENSG00000138755 ENSG00000134853 ENSG00000010278 ENSG00000112715 ENSG00000121807 ENSG00000064300 PMC8250138__F2 Tetraspanins: Novel Molecular Regulators of Gastric Cancer ENSG00000085117 ENSG00000135446 ENSG00000011105 ENSG00000168785 ENSG00000110651 ENSG00000146648 PMC8250138__F1 Tetraspanins: Novel Molecular Regulators of Gastric Cancer ENSG00000138798 ENSG00000127324 ENSG00000214063 ENSG00000146648 PMC6482252__F2 The physiological generation and function of lipid mediators in immunity ENSG00000226275 ENSG00000161533 PMC6482252__F1 Mechanism of foam cell formation ENSG00000135218 ENSG00000130164 ENSG00000125538 ENSG00000160179 ENSG00000075239 PMC4865504__F1 Human and rodent adrenal steroidogenic pathways ENSG00000130164 ENSG00000203859 ENSG00000179142 PMC2856637__F1 Simplified scheme of early FcERI-mediated signaling events ENSG00000033327 ENSG00000167323 ENSG00000010810 ENSG00000010671 PMC3508169__F2 Known relationships between the candidate genes ENSG00000171105 ENSG00000291971 ENSG00000166501 ENSG00000133124 ENSG00000091409 ENSG00000169710 ENSG00000136869 ENSG00000137845 ENSG00000156535 PMC11008418__F8 Silent information regulator sirtuin 1 ameliorates acute liver failure via the p53/glutathione peroxidase 4/gasdermin D axis ENSG00000168003 ENSG00000278718 ENSG00000151012 ENSG00000167468 ENSG00000096717 PMC9016198__F1 Long COVID: The Nature of Thrombotic Sequelae Determines the Necessity of Early Anticoagulation ENSG00000130234 ENSG00000184012 PMC7962940__F7 Role of miR-548m in regulating EMT in breast cancer ENSG00000019549 ENSG00000100985 ENSG00000106546 PMC7376987__F2 Summary of recent advancement toward heart regeneration ENSG00000107562 ENSG00000164093 ENSG00000121966 PMC10535706__F8 Akkermansia muciniphila inhibits tryptophan metabolism via the AhR/Beta-catenin signaling pathway to counter the progression of colorectal cancer ENSG00000129167 ENSG00000168036 ENSG00000106546 PMC7312731__F1 Differential activation of downstream molecules of the insulin-like growth factor (IGF) signaling network ENSG00000002330 ENSG00000169047 ENSG00000168610 ENSG00000089159 PMC3924581__F1 AEG-1/MTDH/LYRIC promotes hepatocarcinogenesis ENSG00000163453 ENSG00000168036 ENSG00000100985 PMC3028977__F6 CD36 contributes to inflammation and impaired insulin signalling in adipocytes and macrophages ENSG00000135218 ENSG00000010810 PMC6434857__F2 Possible therapeutic implications of resveratrol/metformin/exercise in cognition through osteocalcin signalling ENSG00000096717 ENSG00000151025 PMC3414724__F2 Role of the PI3K pathway in B cell antigen presentation functions ENSG00000124102 ENSG00000186716 ENSG00000010671 PMC3414724__F1 Major components of the PI3K pathway in B cells discussed in this review ENSG00000177455 ENSG00000124102 ENSG00000186716 PMC3414724__F4 Alterations in the PI3K pathway in malignant B cells ENSG00000177455 ENSG00000124102 ENSG00000186716 PMC9120413__F7 Annexin-A1 Tripeptide Attenuates Surgery-Induced Neuroinflammation and Memory Deficits Through Regulation the NLRP3 Inflammasome ENSG00000162711 ENSG00000125538 ENSG00000172936 PMC7000863__F1 Unfolded protein response (UPR) pathway ENSG00000128272 ENSG00000144895 ENSG00000198793 PMC7973386__F1 Representation of NAD+biosynthesis pathways ENSG00000187531 ENSG00000105835 ENSG00000278488 ENSG00000124523 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000089163 PMC4454471__F3 Model for generation of repeat expansions during MMR and BER ENSG00000113318 ENSG00000132646 ENSG00000165392 ENSG00000095002 PMC5062167__F8 Combined Transcriptomics and Chemical-Genetics Reveal Molecular Mode of Action of Valproic acid, an Anticancer Molecule using Budding Yeast Model ENSG00000159335 PMC7016612__F3 Crosstalk between primordial follicle activation and DDR pathway ENSG00000149311 ENSG00000012048 ENSG00000157404 ENSG00000133116 ENSG00000051180 ENSG00000139618 PMC7278809__F1 NAD+ biosynthesis pathways ENSG00000105835 ENSG00000291814 ENSG00000278488 PMC7016612__F5 Molecular relationship between phosphoinositide 3-kinase/protein kinase (PTEN/Akt) activation, DNA damage and decreased ovarian reserve ENSG00000188486 ENSG00000149311 ENSG00000104899 PMC8982613__F6 Infantile hepatic hemangiomas: looking backwards and forwards ENSG00000198793 ENSG00000159399 PMC4576203__F2 Participation of HPV oncogenes at different levels of Wnt/Beta-catenin cell signaling regulation ENSG00000134982 ENSG00000168036 ENSG00000196470 ENSG00000136352 ENSG00000099326 PMC4576203__F1 Wnt/Beta-catenin cell signaling pathway ENSG00000134982 ENSG00000168036 PMC8833126__F9 Novel pyroptosis-related signature predicts prognosis and response to treatment in breast carcinoma ENSG00000162711 ENSG00000150782 ENSG00000152661 ENSG00000117228 ENSG00000105550 ENSG00000136696 ENSG00000147697 ENSG00000136688 PMC5056258__F1 PI3K/AKT/mTOR pathway is a critical pro-survival cell signaling pathway within NETs that mediates cell growth and peptide translation ENSG00000198793 PMC10308444__F5 Integrated transcriptome and microRNA sequencing analyses reveal gene responses in poplar leaves infected by the novel pathogen bean common mosaic virus (BCMV) ENSG00000157404 ENSG00000173599 PMC10884126__F8 Interaction networks of “pathways-differentially expressed lncRNAs-target genes” ENSG00000170458 ENSG00000198759 ENSG00000291748 ENSG00000175592 ENSG00000178172 ENSG00000172752 ENSG00000108821 ENSG00000163218 ENSG00000100625 PMC5071376__F2 Diagrammatic representation of the integration of leptin and insulin signals in the regulation of energy homeostasis in the central nervous system ENSG00000115138 ENSG00000168610 PMC5896366__F2 EGF receptor (EGFR) effects on ABC transporters ENSG00000138798 ENSG00000118777 ENSG00000146648 PMC6948191__F3 Combination Cancer Therapy with Immune Checkpoint Blockade: Mechanisms and Strategies ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000163568 ENSG00000135446 ENSG00000148798 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC5477576__F4 Intrinsic apoptosis pathway ENSG00000002330 ENSG00000144895 ENSG00000127191 PMC5477576__F3 Extrinsic apoptosis pathway ENSG00000102871 ENSG00000157625 ENSG00000168040 ENSG00000026103 PMC7379086__F2 Regulatory Effects of O-GlcNAcylation in Vascular Smooth Muscle Cells on Diabetic Vasculopathy ENSG00000147162 ENSG00000198408 PMC3104927__F6 RHIM-dependent signaling ENSG00000183735 ENSG00000173039 ENSG00000136869 ENSG00000164342 PMC9411667__F3 Nrf2-mediated anti-inflammatory polarization of macrophages as therapeutic targets for osteoarthritis ENSG00000162711 ENSG00000115415 ENSG00000198793 ENSG00000172936 ENSG00000105639 ENSG00000175104 ENSG00000168610 ENSG00000156273 ENSG00000079999 PMC9411667__F2 Nrf2-mediated anti-inflammatory polarization of macrophages as therapeutic targets for osteoarthritis ENSG00000162711 ENSG00000137834 ENSG00000148400 ENSG00000115415 ENSG00000198793 ENSG00000172005 ENSG00000172936 ENSG00000105639 ENSG00000175104 ENSG00000168610 PMC9574357__F2 IgA vasculitis update: Epidemiology, pathogenesis, and biomarkers ENSG00000164879 ENSG00000239732 ENSG00000069482 ENSG00000172936 ENSG00000128342 PMC3922145__F3 Differential expression of mTOR and HIF-1A pathways between leiomyoma, HLRCC and leiomyosarcoma ENSG00000198793 PMC8196684__F1 Methylation Patterns of DKK1, DKK3 and GSK3B Are Accompanied with Different Expression Levels in Human Astrocytoma ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC10929826__F8 MUC1 promotes RIF by regulating macrophage ROS-SHP2 signaling pathway to up-regulate inflammatory response and inhibit angiogenesis ENSG00000183735 ENSG00000111537 ENSG00000198793 PMC8085163__F1 Isoprenoid biosynthetic pathway ENSG00000160752 ENSG00000197429 PMC8237035__F1 SARS-CoV-2 signaling pathway map: A functional landscape of molecular mechanisms in COVID-19 ENSG00000120885 PMC3091670__F3 Complement pathway ENSG00000039537 ENSG00000009724 ENSG00000291559 ENSG00000203710 ENSG00000166278 ENSG00000117322 ENSG00000182326 ENSG00000236625 PMC3091670__F2 Interferon signalling cascade ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000183486 ENSG00000157601 ENSG00000232326 ENSG00000185745 ENSG00000185885 ENSG00000125347 ENSG00000230034 ENSG00000007171 PMC4838842__F7 Resveratrol enhances HBV replication through activating Sirt1-PGC-1Alpha-PPARA pathway ENSG00000096717 PMC10523328__F2 Tactile twist: decoding the phenomena of mechanical itch and alloknesis ENSG00000154864 ENSG00000004948 ENSG00000078747 ENSG00000120937 ENSG00000178473 ENSG00000103335 PMC4062953__F2 Classical and non-classical pathways of androgen biosynthesis ENSG00000135437 ENSG00000086696 ENSG00000171234 ENSG00000151632 ENSG00000197888 ENSG00000196620 ENSG00000088002 ENSG00000187134 PMC7835009__F6 VEGFR1-specific signaling pathway that HIF1A participates in ENSG00000140992 ENSG00000110395 ENSG00000129946 ENSG00000198087 ENSG00000143933 ENSG00000112715 ENSG00000124181 ENSG00000118257 ENSG00000179295 PMC4062953__F1 Steroid hormone synthesis pathways in the adrenal gland and testis ENSG00000203859 ENSG00000179142 ENSG00000176387 PMC7774019__F8 EBV early protein BFRF1 inhibiting RLR-mediated IFNB signaling pathway ENSG00000183735 ENSG00000131323 PMC9599947__F2 STAT3 Inhibitors: A Novel Insight for Anticancer Therapy of Pancreatic Cancer ENSG00000172748 ENSG00000168610 ENSG00000146648 PMC6722688__F1 A simplified diagram of the metabolic fate of maternal dietary choline and its delivery to the developing fetus ENSG00000173599 ENSG00000034693 ENSG00000133027 PMC9243343__F2 Mechanism and effect of stress granule formation in cancer and its potential roles in breast cancer therapy ENSG00000198793 ENSG00000067900 PMC4114106__F2 Ubiquitination of RIP1 is an early pro-survival checkpoint in TNF signaling ENSG00000102871 ENSG00000157625 ENSG00000168040 ENSG00000164305 PMC8505648__F4 Targeted therapy of BCBM treatment ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000112715 PMC4034039__F5 Proposed lignin degradation pathway in C ENSG00000187475 ENSG00000166278 PMC6278600__F1 Postulated cellular mechanisms of 20-HETE bioactions in the blood vessel wall ENSG00000119737 ENSG00000146648 PMC5392205__F10 Atorvastatin inhibits the immediate-early response gene EGR1 and improves the functional pro of CD4+T-lymphocytes in acute coronary syndromes ENSG00000172936 ENSG00000136869 ENSG00000121807 PMC12175327__F1 Neutrophils interact with CTCs through both direct and indirect mechanisms ENSG00000198053 ENSG00000163739 ENSG00000162692 PMC11032202__F6 Intratumoural heterogeneity informs intertumoural heterogeneity ENSG00000134086 PMC11032202__F3 Oncogenes versus tumour suppressor genes in glioblastoma ENSG00000136997 ENSG00000121879 ENSG00000146648 ENSG00000139687 ENSG00000196712 PMC12175327__F4 Nanomaterials for driving neutrophil repolarization toward the N1 phenotype, degrading ENTs and modulating neutrophil infiltration ENSG00000164430 ENSG00000121058 ENSG00000214285 ENSG00000100985 PMC3499024__F2 Bone anabolism regulated by statins ENSG00000163914 PMC5140697__F1 Targeting cancer metabolism: dietary and pharmacological interventions ENSG00000131473 ENSG00000092621 ENSG00000198793 ENSG00000136997 ENSG00000169710 ENSG00000146733 ENSG00000115419 PMC4965903__F1 IL-7RA pathway mutations provide potential targets for acute lymphoblastic leukemia therapy ENSG00000198793 ENSG00000145777 PMC5140697__F2 Targeting cancer metabolism: dietary and pharmacological interventions ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC4673467__F2 Wnt signaling pathways ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC9382782__F2 Dual roles of interleukin-33 in cognitive function by regulating central nervous system inflammation ENSG00000108691 ENSG00000137033 PMC7612338__F1 ISR signaling pathway ENSG00000128272 ENSG00000144895 ENSG00000162600 ENSG00000154059 ENSG00000081791 PMC8505648__F3 Interactions between cancer cells and resident cells ENSG00000115415 ENSG00000136997 ENSG00000171791 ENSG00000146648 ENSG00000182793 ENSG00000026103 PMC8613896__F2 New perspectives on the treatment of hidradenitis suppurativa ENSG00000169248 ENSG00000162711 ENSG00000108691 ENSG00000163739 ENSG00000169429 ENSG00000124875 ENSG00000115009 PMC6886244__F1 Scheme of the N-linked glycosylation pathway ENSG00000101901 ENSG00000254685 ENSG00000120697 ENSG00000151092 ENSG00000095380 ENSG00000159921 ENSG00000170191 ENSG00000111726 ENSG00000173540 ENSG00000253710 ENSG00000119523 ENSG00000112699 ENSG00000182858 ENSG00000084774 ENSG00000013375 PMC7016612__F2 DNA double-strand breaks (DSBs) response pathway ENSG00000149311 ENSG00000135446 ENSG00000123374 ENSG00000051180 ENSG00000100206 ENSG00000171791 ENSG00000139618 PMC3370283__F2 Somatic Activating PIK3CA Mutations in CLOVES Syndrome(A) Demonstration of the PIK3CA c.1624G>A somatic mosaic mutation in participant CL4 ENSG00000198793 ENSG00000121879 PMC10990851__F9 Integrated transcriptomic and metabolomic analysis reveals the regulation mechanism of early bolting and flowering in two cultivars of Angelica sinensis ENSG00000163435 ENSG00000203783 ENSG00000131188 PMC10990851__F8 Metabolic pathway map of biosynthesis related to photosynthesis ENSG00000182511 ENSG00000002330 ENSG00000173599 PMC10148099__F7 Metabolic role of the hepatic valine/3-hydroxyisobutyrate (3-HIB) pathway in fatty liver disease ENSG00000073578 ENSG00000117118 ENSG00000060982 ENSG00000176715 ENSG00000169710 ENSG00000163541 ENSG00000138356 ENSG00000100412 ENSG00000113790 ENSG00000146701 ENSG00000105552 ENSG00000091140 ENSG00000062485 ENSG00000117305 ENSG00000124370 ENSG00000105953 ENSG00000172340 ENSG00000101365 ENSG00000111058 ENSG00000172497 ENSG00000175198 ENSG00000137992 ENSG00000114054 ENSG00000198125 ENSG00000122971 PMC3006139__F6 Subversion of Innate Defenses by the Interplay between DENV and Pre-Existing Enhancing Antibodies: TLRs Signaling Collapse ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC8046925__F6 Visual pigment cycle reactions in vertebrate and invertebrate photoreceptors: (A) Pathways for visual pigment regeneration in the vertebrate retina, including both the classical and non-classical pathways ENSG00000121207 ENSG00000197713 PMC8511580__F1 Biological signaling networks related to PM10 & PM2.5 exposure inducing skin-related cellular processes and diseases ENSG00000115718 ENSG00000112715 ENSG00000136826 ENSG00000137801 ENSG00000041982 ENSG00000186847 ENSG00000125398 ENSG00000164400 ENSG00000128342 ENSG00000137440 ENSG00000081041 ENSG00000108342 ENSG00000134363 ENSG00000173039 ENSG00000213341 ENSG00000099194 ENSG00000127191 ENSG00000087460 ENSG00000277943 ENSG00000132170 ENSG00000197461 ENSG00000169245 ENSG00000108691 ENSG00000177606 ENSG00000005381 ENSG00000146648 ENSG00000115009 PMC4905302__F1 Autophagy regulatory pathway ENSG00000152348 ENSG00000126775 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC3721080__F6 Spatio-temporal analysis of type 2 diabetes mellitus based on differential expression networks ENSG00000198793 ENSG00000166278 ENSG00000102104 ENSG00000127948 ENSG00000214140 PMC4811737__F1 Cellular and molecular mechanisms implicated in regulating the balance between tolerance and rejection in the mouse liver transplant model ENSG00000111537 ENSG00000026103 PMC5460589__F2 The folate biosynthesis pathway and its compartmentalisation in plants (modified from ) ENSG00000228716 ENSG00000095059 ENSG00000136877 PMC2710681__F4 Model describing TLS across CPD in human cells ENSG00000122008 ENSG00000122678 PMC2773638__F4 Coordination of extracellular and intracellular signaling regulates cytoskeletal dynamics and axon formation ENSG00000070831 ENSG00000134982 PMC5112569__F6 Regulation of Sirt1/Nrf2/TNFA signaling pathway by luteolin is critical to attenuate acute mercuric chloride exposure induced hepatotoxicity ENSG00000088727 ENSG00000102871 ENSG00000198793 ENSG00000096717 ENSG00000079999 PMC4736967__F1 Wnt/Beta-catenin signaling in ASDs ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC5540363__F1 Oxygen regulation of ESC metabolism and epigenetic landscape ENSG00000159921 ENSG00000145321 PMC2684849__F3 Transcriptional regulation of human small nuclear RNA genes ENSG00000104221 ENSG00000274803 PMC11703929__F1 Mitochondrial damage causes inflammation via cGAS-STING signaling in ketamine-induced cystitis ENSG00000183735 ENSG00000164430 PMC5082570__F1 Mammalian choline degradation pathway with DMGDH as metabolic branch point ENSG00000002330 ENSG00000179761 PMC8450567__F5 Transcriptome Analysis of Immune Receptor Activation and Energy Metabolism Reduction as the Underlying Mechanisms in Interleukin-6-Induced Skeletal Muscle Atrophy PMC4941269__F4 Repulsive guidance molecule B inhibits metastasis and is associated with decreased mortality in non-small cell lung cancer ENSG00000124216 ENSG00000002330 ENSG00000125968 PMC8546664__F2 Alterations of DNA damage response pathway: Biomarker and therapeutic strategy for cancer immunotherapy ENSG00000149311 ENSG00000175054 ENSG00000164430 ENSG00000111537 PMC8546664__F1 Alterations of DNA damage response pathway: Biomarker and therapeutic strategy for cancer immunotherapy ENSG00000104884 ENSG00000039650 ENSG00000163918 ENSG00000115350 ENSG00000077514 ENSG00000274675 ENSG00000012048 ENSG00000292191 ENSG00000132781 ENSG00000148229 ENSG00000104320 ENSG00000204086 ENSG00000166169 ENSG00000111358 ENSG00000109674 ENSG00000292286 ENSG00000275045 ENSG00000157216 ENSG00000139618 ENSG00000102699 ENSG00000134574 ENSG00000132646 ENSG00000151164 ENSG00000139842 ENSG00000100479 ENSG00000136936 ENSG00000188827 ENSG00000291803 ENSG00000277273 ENSG00000134480 ENSG00000175054 ENSG00000113318 ENSG00000132383 ENSG00000170430 ENSG00000139372 ENSG00000129071 ENSG00000177084 ENSG00000106628 ENSG00000253729 ENSG00000107447 ENSG00000149311 ENSG00000272047 ENSG00000165392 ENSG00000197299 ENSG00000041880 ENSG00000133119 ENSG00000095002 ENSG00000047315 ENSG00000122678 ENSG00000122512 PMC7789510__F6 Simplified schema and functions of SAUR genes in plant evolution ENSG00000165527 PMC9604794__F15 Network Pharmacological Analysis of the Red Sea Sponge Hyrtios erectus Extract to Reveal Anticancer Efficacy of Corresponding Loaded Niosomes ENSG00000112977 ENSG00000172680 ENSG00000166402 PMC3214273__F1 Pathogenic microbes and community service through manipulation of innate immunity ENSG00000174125 ENSG00000164879 ENSG00000136869 ENSG00000121966 PMC7606465__F7 Next-generation sequencing analysis of circulating micro-RNA expression in response to parabolic flight as a spaceflight analogue ENSG00000149311 ENSG00000135446 ENSG00000123374 PMC6050486__F5 Schematic drawing of epigenetic reprogramming in Dnmts, Sfrp4 and Wnt/B‐catenin pathway from the foetus to offspring ENSG00000162337 ENSG00000134982 ENSG00000175592 ENSG00000106483 PMC7541692__F1 Dysregulation of the mitogen-activated protein kinase (MAPK) signaling pathway in melanoma ENSG00000157764 ENSG00000196712 PMC7586430__F2 Regulation and functions of NEDD4 E3 ligases in cardiac disease ENSG00000170365 ENSG00000065978 ENSG00000105329 ENSG00000134057 ENSG00000078747 ENSG00000265972 ENSG00000145386 ENSG00000123124 PMC9162043__F7 Receptor for activated C kinase 1 promotes cervical cancer lymph node metastasis via the glycolysis-dependent AKT/mTOR signaling ENSG00000028277 ENSG00000198793 ENSG00000159399 ENSG00000140443 PMC7586430__F1 Ubiquitination-proteasome of NEDD4 E3 ligases pathway ENSG00000069869 ENSG00000078747 ENSG00000123124 PMC3919808__F9 Pathophysiology of Acute Kidney Injury ENSG00000168040 ENSG00000115317 ENSG00000026103 PMC7586430__F3 Regulation and functions of NEDD4 E3 ligases in vascular disease ENSG00000108387 ENSG00000105329 ENSG00000198742 PMC6159944__F9 Schematic pathway representing findings of this study ENSG00000135218 ENSG00000160179 ENSG00000135929 ENSG00000026103 ENSG00000262243 PMC6834859__F1 Effect of GPCRs on RTK transactivation ENSG00000291971 ENSG00000198793 ENSG00000146648 PMC5866970__F2 Regulation of the Hippo pathway in endothelial cells ENSG00000163914 ENSG00000162692 PMC5653513__F2 PD1-dependent inhibitory mechanisms ENSG00000291603 ENSG00000078747 ENSG00000123374 PMC5866970__F1 Components of the Hippo/YAP pathway ENSG00000150457 ENSG00000131023 PMC7937835__F3 Lessons from mitochondrial proteostasis in adipose tissue ENSG00000128272 ENSG00000169136 ENSG00000130513 PMC9138536__F2 Central and Peripheral Immune Dysregulation in Posttraumatic Stress Disorder: Convergent Multi-Omics Evidence ENSG00000182718 ENSG00000185634 ENSG00000081041 ENSG00000291603 ENSG00000065675 ENSG00000271605 ENSG00000099985 ENSG00000122574 ENSG00000000971 ENSG00000187764 ENSG00000095585 ENSG00000169245 ENSG00000163131 ENSG00000163734 ENSG00000145321 ENSG00000123374 ENSG00000184988 ENSG00000136869 ENSG00000198771 PMC5866970__F3 Regulation of the Hippo pathway in smooth muscle cells ENSG00000163914 ENSG00000136997 PMC2586935__F4 TGFB pathway as affected by IGF2 administration based on Pathway-Express ENSG00000170365 ENSG00000137834 ENSG00000111537 ENSG00000100387 ENSG00000198742 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000067900 ENSG00000164093 ENSG00000205250 ENSG00000137801 PMC5889571__F2 CD109 and TGFB signaling ENSG00000156535 PMC3562293__F2 Choline-releasing glycerophosphodiesterase EDI3 links the tumor metabolome to signaling network activities ENSG00000198793 ENSG00000163914 ENSG00000173599 ENSG00000198670 PMC8213678__F8 Discovery and function exploration of microRNA-155 as a molecular biomarker for early detection of breast cancer ENSG00000113456 ENSG00000113494 PMC7487321__F3 Oxygen-dependent pathway of plasmalogens biosynthesis in animals ENSG00000173599 ENSG00000197601 ENSG00000026103 PMC2453072__F3 The relationship between dNTP pool levels and mutagenesis in an Escherichia coli NDP kinase mutant ENSG00000161634 ENSG00000128951 PMC10573127__F3 Secretory cell (SC) differentiation programs ENSG00000168447 ENSG00000170608 ENSG00000161798 ENSG00000050628 ENSG00000169550 ENSG00000205835 ENSG00000168878 ENSG00000136826 ENSG00000291363 ENSG00000016490 ENSG00000133661 ENSG00000001626 ENSG00000116990 ENSG00000124664 ENSG00000234602 PMC10573127__F2 Molecular pathways involved in multiciliogenesis ENSG00000148400 ENSG00000152669 ENSG00000171444 ENSG00000129654 ENSG00000087903 ENSG00000205250 ENSG00000234602 ENSG00000080298 PMC10573127__F1 Airway epithelial differentiation pathways ENSG00000087903 ENSG00000164287 ENSG00000165325 ENSG00000170465 ENSG00000080298 ENSG00000186081 ENSG00000291363 ENSG00000186847 ENSG00000078900 ENSG00000152669 ENSG00000001626 ENSG00000117983 ENSG00000124664 ENSG00000170477 ENSG00000186832 PMC2676730__F5 The Pathway Less Traveled: Moving from Candidate Genes to Candidate Pathways in the Analysis of Genome-Wide Data from Large Scale Pharmacogenetic Association Studies PMC5006437__F1 Regulation of molecules in the NMDAR signaling pathway on learning and memory ENSG00000198576 PMC5799812__F6 A convergent model for the pathogenesis of ANKL ENSG00000136997 PMC6996369__F6 Scheme of predicted AJP001 signaling and the antibody production induced by the AJP001 conjugate peptide vaccine ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC2959043__F3 Wnt/Beta-catenin signaling Ctenophore pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC2688747__F4 Fgf and Sdf-1 Pathways Interact during Zebrafish Fin Regeneration ENSG00000111186 ENSG00000077782 PMC9477422__F7 Ptprh mutant mouse tumors failing to dephosphorylate EGFR ENSG00000080031 ENSG00000123374 ENSG00000146648 PMC7707548__F6 Inhibition of the de novo pyrimidine biosynthesis pathway limits ribosomal RNA transcription causing nucleolar stress in glioblastoma cells ENSG00000188486 ENSG00000145321 ENSG00000170430 ENSG00000102967 PMC2724309__F2 Steroidogenesis pathway: Steroids are in bold; enzymes and cholesterol transport proteins are in italics PMC8236385__F1 Research progress on Toll-like receptor signal transduction and its roles in antimicrobial immune responses ENSG00000172005 ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC4063840__F2 In vivo gut transcriptome responses to Lactobacillus rhamnosus GG and Lactobacillus acidophilus in neonatal gnotobiotic piglets ENSG00000111837 ENSG00000189403 PMC6892982__F1 Autophagy regulators and functions associated with anti-aging effects ENSG00000188554 ENSG00000083635 ENSG00000112561 ENSG00000069509 PMC4002088__F7 Schematic representation of the proposed novel TXNIP/miR-124a/FOXA2/IAPP signaling pathway ENSG00000121351 ENSG00000265972 PMC9287895__F3 Emerging strategies to overcome resistance to third-generation EGFR inhibitors ENSG00000167601 ENSG00000291971 ENSG00000198793 ENSG00000136997 ENSG00000047936 ENSG00000168610 ENSG00000146648 PMC3936199__F3 Iron homeostasis in the liver ENSG00000245848 ENSG00000010704 ENSG00000106327 ENSG00000187045 ENSG00000187266 ENSG00000168610 PMC5344902__F2 Type I interferon (IFN) signaling ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC5344902__F1 Pattern recognition receptor signaling that leads to the induction of type I interferons (IFNs) ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000102871 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC5316308__F2 DREAM as a novel therapeutic target for anti-thrombotic agents ENSG00000213658 ENSG00000291971 ENSG00000010810 ENSG00000197943 ENSG00000135605 ENSG00000010671 PMC12250001__F3 Principal microRNAs and targets involved in inflammation and cartilage destruction in OA ENSG00000154736 ENSG00000126453 ENSG00000149968 ENSG00000113070 ENSG00000185591 ENSG00000162692 ENSG00000096717 PMC6551314__F8 Proposed model for the role of Them2 in hepatic VLDL secretion ENSG00000042832 ENSG00000158669 ENSG00000285482 ENSG00000198670 ENSG00000062282 PMC2691965__F2 Toll-like receptor (TLR) activation ENSG00000174125 ENSG00000170458 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC7880350__F8 Schematic illustration the contribution of FGF23 induced by post-infarct heart failure to promoting renal fibrosis ENSG00000118972 ENSG00000160867 ENSG00000015285 ENSG00000168036 PMC5497057__F2 Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer ENSG00000149311 ENSG00000171105 ENSG00000134982 ENSG00000135446 ENSG00000198793 ENSG00000134853 ENSG00000168036 ENSG00000105810 ENSG00000146648 ENSG00000139687 ENSG00000196712 PMC12250001__F2 Principal molecular mechanisms involved in the MAPK, NFKB, and PI3K/Akt signaling pathways activated by oxidative stress in OA ENSG00000154736 ENSG00000155090 PMC11942346__F1 Mechanisms of adhesion formation: (1) Inhibition of fibrinolysis and ECM deposition ENSG00000122194 PMC9465188__F1 Recent advances in the therapeutic efficacy of hepatocyte growth factor gene‐modified mesenchymal stem cells in multiple disease settings ENSG00000019991 ENSG00000170989 ENSG00000162692 ENSG00000049768 ENSG00000121966 PMC6767550__F2 Canonical and noncanonical signaling pathways of NOD1 and NOD2 ENSG00000183735 ENSG00000088888 ENSG00000167207 ENSG00000106100 PMC8606592__F1 Long Non-Coding RNAs in Epithelial-Mesenchymal Transition of Pancreatic Cancer ENSG00000253352 PMC6986015__F9 Schematic depiction of main conclusions ENSG00000128272 ENSG00000064012 ENSG00000164305 PMC3648641__F1 Unraveling Mechanisms Regulating Systemic Iron Homeostasis ENSG00000010704 ENSG00000106327 ENSG00000187045 PMC4661576__F1 The fate of chemoresistance in triple negative breast cancer (TNBC) ENSG00000118777 ENSG00000095002 PMC6981617__F2 General metabolism and elemental sulfur-mediated cellular responses in Palaeococcus pacificus DY20341T ENSG00000182511 ENSG00000169291 ENSG00000198931 ENSG00000184207 ENSG00000127948 PMC6180304__F2 Three key innate immune pathways for the most common retinal degenerative diseases ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000161640 ENSG00000142166 PMC6743306__F6 Proposed model illustrating the roles of CHL1 during NPC carcinogenesis ENSG00000070831 ENSG00000134121 PMC1899901__F6 A schematic model depicting the role of Artemis in the cellular response to IR ENSG00000149311 ENSG00000166851 PMC5003840__F1 Proposed biosynthetic pathway to the synthesis of xanthanolides ENSG00000100473 ENSG00000291507 ENSG00000150787 PMC9239773__F6 Identification of CXCR4 Upregulation in Diffuse Large B-Cell Lymphoma Associated with Prognostic Significance and Clinicopathological Characteristics ENSG00000107562 PMC151822__F2 Signaling UPR-mediated cell death ENSG00000128272 ENSG00000127191 PMC10177044__F2 Ratio of p38 signaling to ERK determines whether cancer cells enter a dormant state or undergo proliferation ENSG00000019991 ENSG00000087245 ENSG00000161921 ENSG00000134013 ENSG00000100985 ENSG00000266524 ENSG00000121966 PMC6736652__F1 Predictive biomarkers for bevacizumab efficacy in breast cancer ENSG00000087245 ENSG00000100985 ENSG00000112715 ENSG00000167508 PMC8465904__F4 Crosstalk of the Wnt/Beta-Catenin Signaling Pathway in the Induction of Apoptosis on Cancer Cells ENSG00000134982 ENSG00000168036 ENSG00000168040 ENSG00000026103 PMC8465904__F3 Crosstalk of the Wnt/Beta-Catenin Signaling Pathway in the Induction of Apoptosis on Cancer Cells ENSG00000175336 ENSG00000026103 PMC9684870__F3 Disease-specific tissue glycosylation ENSG00000108691 ENSG00000134982 ENSG00000130714 PMC8465904__F2 Crosstalk of the Wnt/Beta-Catenin Signaling Pathway in the Induction of Apoptosis on Cancer Cells ENSG00000019991 ENSG00000087245 ENSG00000101751 ENSG00000137673 ENSG00000134982 ENSG00000005882 ENSG00000138798 ENSG00000108342 ENSG00000168036 ENSG00000150457 ENSG00000131023 ENSG00000132646 ENSG00000026508 ENSG00000184371 ENSG00000164400 ENSG00000100985 ENSG00000146648 PMC9237610__F1 Genetic Manipulation of Biosynthetic Pathways in Mint ENSG00000082175 ENSG00000113161 PMC5407862__F1 Management of EGFR-mutated non-small-cell lung cancer: practical implications from a clinical and pathology perspective ENSG00000019991 ENSG00000157764 ENSG00000198793 ENSG00000146648 PMC8465904__F1 Crosstalk of the Wnt/Beta-Catenin Signaling Pathway in the Induction of Apoptosis on Cancer Cells ENSG00000070831 ENSG00000134982 ENSG00000163914 ENSG00000168036 ENSG00000163631 PMC2423297__F9 The role of cAMP-stimulated adipogenesis via PKA- end Epac1-dependent processes ENSG00000163914 PMC9217905__F1 Molecular Pathogenesis of Sporadic Desmoid Tumours and Its Implications for Novel Therapies: A Systematised Narrative Review ENSG00000137673 ENSG00000134982 ENSG00000168036 PMC6367888__F6 Gene-pathway network of 26 DEGs ENSG00000169245 ENSG00000134321 ENSG00000117228 ENSG00000187608 ENSG00000157601 ENSG00000135114 PMC3387493__F1 Dual Aspects of Altered Bone Remodeling in Psoriatic Arthritis ENSG00000187764 ENSG00000010671 PMC2910898__F1 During normoxia, HIF-1A is rapidly degraded by the ubiquitin-proteasome pathway PMC10380201__F7 Small-Extracellular-Vesicle-Derived miRNA Profile Identifies miR-483-3p and miR-326 as Regulators in the Pathogenesis of Antiphospholipid Syndrome (APS) ENSG00000117525 ENSG00000198793 ENSG00000162692 PMC6522926__F5 Schematic representation of the E2/ESR1/CD36/PPARA pathway in skeletal muscle cells ENSG00000135218 ENSG00000042832 ENSG00000169710 PMC9217905__F6 Molecular Pathogenesis of Sporadic Desmoid Tumours and Its Implications for Novel Therapies: A Systematised Narrative Review ENSG00000137673 ENSG00000134982 ENSG00000168036 PMC5902023__F1 Mammalian isoprenoid biosynthetic pathway with associated inhibitors ENSG00000160752 ENSG00000163914 ENSG00000197429 PMC3091595__F2 Bcl-2 as an attractive target for modulating different modes of cell death in cancer therapy due to close communications with mediators of apoptosis, programmed necrosis, and autophagy ENSG00000102871 ENSG00000168040 PMC3947362__F7 The proposed model for the signaling events in mature, human oligodendrocytes in response to B. burgdorferi ENSG00000108691 ENSG00000169429 PMC8753521__F5 Recent progress (2015–2020) in the investigation of the pharmacological effects and mechanisms of ginsenoside Rb1, a main active ingredient in Panax ginseng Meyer ENSG00000087095 ENSG00000147162 ENSG00000198793 ENSG00000198626 ENSG00000112715 ENSG00000168610 ENSG00000023909 ENSG00000121966 ENSG00000163914 ENSG00000159346 ENSG00000189403 ENSG00000285070 ENSG00000096717 ENSG00000139687 ENSG00000060762 PMC9217541__F7 Study the Mechanism of Gualou Niubang Decoction in Treating Plasma Cell Mastitis Based on Network Pharmacology and Molecular Docking ENSG00000082175 ENSG00000291748 ENSG00000007908 ENSG00000125347 ENSG00000132170 PMC8045279__F1 Leptin signaling pathways ENSG00000173599 ENSG00000115138 ENSG00000168610 PMC9368893__F3 Molecular Mechanisms Underlying Intensive Care Unit-Acquired Weakness and Sarcopenia ENSG00000198793 PMC7869230__F9 IL-17 signaling pathway cascades obtained from the global proteome data by KEGG pathway analysis ENSG00000102871 ENSG00000105656 ENSG00000168040 ENSG00000155313 ENSG00000127191 ENSG00000163702 ENSG00000076604 ENSG00000152430 ENSG00000172458 ENSG00000108691 ENSG00000149968 ENSG00000108688 ENSG00000026508 ENSG00000100985 ENSG00000056736 ENSG00000175104 PMC9631787__F1 Plant polysaccharides with anti-lung injury effects as a potential therapeutic strategy for COVID-19 ENSG00000130234 ENSG00000172936 ENSG00000005381 PMC2172900__F9 A model of how the Tor1/2 and Lst8 proteins affect amino acid biosynthesis and Gap1p sorting ENSG00000011143 PMC9631787__F3 Plant polysaccharides with anti-lung injury effects as a potential therapeutic strategy for COVID-19 ENSG00000105329 ENSG00000130234 ENSG00000138798 ENSG00000170558 ENSG00000198793 ENSG00000175104 PMC4524397__F5 Role of Regulatory T Cells (Treg) and the Treg Effector Molecule Fibrinogen-like Protein 2 in Alloimmunity and Autoimmunity ENSG00000181847 ENSG00000049768 PMC3119514__F3 IL-1 and TLR activation pathways ENSG00000183735 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000115594 PMC7710592__F1 Short-term heritable variation overwhelms two hundred generations of mutational variance for metabolic traits in Caenorhabditis elegans ENSG00000156110 ENSG00000196839 ENSG00000198931 PMC3119514__F2 TNFA and TCR activation pathways ENSG00000141527 ENSG00000291603 ENSG00000187796 ENSG00000102871 ENSG00000082512 ENSG00000168040 ENSG00000124181 ENSG00000175104 ENSG00000127191 ENSG00000100065 PMC6650964__F5A Proteomic Analysis of Morphologically Changed Tissues after Prolonged Dexamethasone Treatment ENSG00000122566 ENSG00000157087 ENSG00000183020 ENSG00000124795 ENSG00000134108 PMC3177043__F2 Different pathways of myostatin signalling ENSG00000198793 PMC3119514__F6 RNA polymerase II transcription complex ENSG00000056558 ENSG00000185591 PMC5266810__F1 Interorgan crosstalk involved in Beta-cell failure ENSG00000121351 ENSG00000125538 PMC8014382__F1 Tumor cell and T cells: the pathways that involve MDSC cells, CD8+ T cells, Tumor cells, NK cells and chemotherapy drugs were constructed ENSG00000157404 ENSG00000134982 ENSG00000112715 PMC5054393__F7 Differential transcriptional responses to Ebola and Marburg virus infection in bat and human cells ENSG00000159128 ENSG00000280962 ENSG00000157077 ENSG00000138166 ENSG00000115415 ENSG00000120875 ENSG00000143507 ENSG00000291431 ENSG00000198793 ENSG00000137193 PMC7212460__F2 Canonical Wnt/Beta-catenin pathway ENSG00000134982 ENSG00000168036 PMC4636403__F5 Investigation into the effects of antioxidant-rich extract of Tamarindus indica leaf on antioxidant enzyme activities, oxidative stress and gene expression profiles in HepG2 cells ENSG00000113889 ENSG00000003436 ENSG00000110799 ENSG00000157601 ENSG00000122194 ENSG00000185010 ENSG00000180210 ENSG00000126218 ENSG00000101981 ENSG00000117525 ENSG00000116133 ENSG00000175899 ENSG00000198734 ENSG00000276838 ENSG00000168765 PMC3129504__F2 Ras/Raf/mitogen-activated protein kinase pathway ENSG00000157764 ENSG00000138798 ENSG00000146648 PMC8014382__F2 APC cells and T cells: the pathways that involve OX40/OX40L, PD-1/PD-L1, mTOR/Akt, NKKB/NFAT and Cyclin A/CDK were analyzed ENSG00000123685 ENSG00000187531 ENSG00000134982 ENSG00000156127 ENSG00000198793 ENSG00000113520 ENSG00000049768 ENSG00000096717 PMC6395653__F3 The metabolic network ENSG00000122966 ENSG00000172005 ENSG00000099864 PMC7912842__F1 Fibroblast growth factor-FGF receptor (FGF-FGFR) and cyclin D-cyclin-dependent kinase (CDK)4/6 pathways in breast cancer ENSG00000039537 ENSG00000135446 ENSG00000198793 ENSG00000168036 ENSG00000123374 ENSG00000105810 ENSG00000163661 PMC3548172__F3 Cooperation of esBAF and PRC2 during pluripotency maintenance ENSG00000128342 ENSG00000168610 PMC7407918__F3 Signaling pathways involved in exacerbating oxidative damage and liver injury ENSG00000170458 ENSG00000102871 ENSG00000125538 ENSG00000086991 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC8164580__F1 Neuronal dysfunction in HIV-associated neurocognitive disorders ENSG00000107562 ENSG00000291971 ENSG00000121966 PMC4277124__F12 Proposed underlying mechanism for the effect of SCE on drug metabolizing enzymes and drug transporters via Nrf2-mediated signaling pathway ENSG00000170899 ENSG00000181019 ENSG00000178573 ENSG00000023909 ENSG00000079999 PMC11003951__F8 Inflammatory Factor IL1A Induces Aberrant Astrocyte Proliferation in Spinal Cord Injury Through the Grin2c/Ca2+/CaMK2b Pathway ENSG00000115008 PMC8825588__F2 Tumor-derived extracellular vesicles as messengers of natural products in cancer treatment ENSG00000149311 ENSG00000175054 ENSG00000106683 ENSG00000134982 ENSG00000163599 ENSG00000198793 ENSG00000136997 ENSG00000166278 ENSG00000171791 ENSG00000165527 ENSG00000168040 PMC12222815__F7 GCRSZXD- Chinese herb - active ingredient - hub gene - signaling pathway – disease network ENSG00000291971 ENSG00000145321 ENSG00000146648 PMC8825588__F5 Tumor-derived extracellular vesicles as messengers of natural products in cancer treatment ENSG00000178860 ENSG00000136869 PMC4367656__F1 Physiological changes with aging () ENSG00000198793 ENSG00000096717 PMC8164580__F2 Neuronal dysfunction in HIV-associated neurocognitive disorders ENSG00000291971 ENSG00000125538 PMC4592361__F7 Involvement of LRP6 in the PTH-stimulated anabolic bone effect ENSG00000152266 ENSG00000281324 ENSG00000167941 ENSG00000168036 PMC8072315__F1 Major signaling pathways and key mediators of macrophages in acute kidney injury ENSG00000198793 ENSG00000136869 ENSG00000105639 ENSG00000168610 PMC7059563__F4 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis.A KEGG pathway analysis revealed 15 substantially enriched pathways corresponding to transcripts dysregulated after spinal cord injury (SCI) ENSG00000102871 ENSG00000128342 ENSG00000164305 PMC4278302__F6 Acellular fraction of ovarian cancer ascites induce apoptosis by activating JNK and inducing BRCA1, Fas and FasL expression in ovarian cancer cells ENSG00000012048 ENSG00000026103 PMC8566438__F1 Where the Aryl Hydrocarbon Receptor Meets the microRNAs: Literature Review of the Last 10 Years ENSG00000110711 ENSG00000291971 ENSG00000106546 PMC9112604__F3 Endotheliitis, Shunts, and Ventilation–Perfusion Mismatch in Coronavirus Disease 2019: A Literature Review of Disease Mechanisms ENSG00000140564 ENSG00000130234 ENSG00000184012 PMC8083806__F2 An update on genetic basis of generalized pustular psoriasis (Review) ENSG00000141527 ENSG00000081041 ENSG00000152056 ENSG00000100448 ENSG00000127954 ENSG00000163739 ENSG00000172936 ENSG00000005381 ENSG00000136695 PMC2783576__F2 Mitotic removal of cohesin in humans: In humans, cohesins (pink) are removed from chromosome arms in prophase in a Plk1-dependent pathway ENSG00000108055 ENSG00000134982 ENSG00000166851 PMC6523301__F1 Main cellular protein clearance mechanisms, the ubiquitin–proteasome system (UPS), and the autophagy pathway ENSG00000152348 ENSG00000126775 ENSG00000163902 ENSG00000144848 ENSG00000145782 ENSG00000291973 ENSG00000057663 PMC5823444__F8 Microsomal prostaglandin E synthase-1 gene deletion impairs neuro-immune circuitry of the cholinergic anti-inflammatory pathway in endotoxaemic mouse spleen ENSG00000125538 PMC3942890__F1 ER stress signaling pathway ENSG00000128272 ENSG00000144895 PMC9424857__F1 Entner-Doudoroff pathway in Synechocystis PCC 6803: Proposed regulatory roles and enzyme multifunctionalities ENSG00000261701 ENSG00000115718 PMC11560437__F4 Aquaporins in sepsis- an update ENSG00000103569 ENSG00000185591 PMC6498404__F4 High-affinity IgE is derived from the CD80+ pro-PC subset of IgG1 memory cells in mouse memory responses ENSG00000150907 ENSG00000173599 ENSG00000145321 ENSG00000112182 PMC5705153__F8 Cisplatin or LA-12 enhance killing effects of TRAIL in prostate cancer cells through Bid-dependent stimulation of mitochondrial apoptotic pathway but not caspase-10 ENSG00000168040 PMC5207552__F1 Identified molecular mechanism of interaction between environmental risk factors and differential expression genes in cartilage of Kashin–Beck disease ENSG00000002330 ENSG00000153094 ENSG00000105401 ENSG00000138794 ENSG00000108551 ENSG00000064393 ENSG00000171791 ENSG00000157240 ENSG00000100290 ENSG00000133110 ENSG00000115457 ENSG00000141753 ENSG00000277897 PMC11488446__F2 Alterations in the WNT/PCP Signalling Pathway During the Progression of OA ENSG00000004975 ENSG00000107404 ENSG00000100592 ENSG00000173218 ENSG00000075275 ENSG00000008300 ENSG00000179431 ENSG00000161202 PMC9025114__F3 Selectin-Mediated Signaling—Shedding Light on the Regulation of Integrin Activity in Neutrophils ENSG00000291971 ENSG00000197943 ENSG00000010671 PMC8463915__F2 Diverse roles of TMEM16A Ca2+-activated Cl− channels in inflammation ENSG00000138798 ENSG00000136869 ENSG00000168610 ENSG00000146648 PMC7205878__F2 Autophagy and microbial pathogenesis ENSG00000168404 ENSG00000137845 ENSG00000145782 ENSG00000057663 PMC4986634__F7 Mechanism of hepatocarcinogenesis promotion via HBV-induced ROS accumulation ENSG00000168610 PMC3527322__F1 Amniotic fluid stem cells to study mTOR signaling in differentiation ENSG00000177169 ENSG00000106070 ENSG00000198793 ENSG00000169047 ENSG00000118515 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC8198588__F2 Cellular and Chemical Biology of Endocytic Trafficking and Intracellular Delivery—The GL–Lect Hypothesis ENSG00000069482 ENSG00000176597 ENSG00000008513 ENSG00000147869 ENSG00000135454 ENSG00000111728 ENSG00000101638 ENSG00000183778 ENSG00000158470 ENSG00000115525 PMC3726008__F5 Dose-dependent MeHg-induced gene expression alterations within the Wnt-signaling pathway ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000060982 ENSG00000104332 ENSG00000100888 ENSG00000177565 ENSG00000157240 ENSG00000100592 ENSG00000101849 ENSG00000100387 ENSG00000113558 ENSG00000075275 PMC8210554__F3 Circular RNAs as novel potential biomarkers for pancreatic cancer ENSG00000108821 PMC5423134__F9 Proposed mechanism of action by the combination of VCP inhibitors and ER stress‐prolonging agent Salubrinal ENSG00000128272 ENSG00000144895 ENSG00000165280 PMC3586206__F1 Schematic summarizing the effects of MIF on the canonical MAPK pathways ENSG00000019582 ENSG00000121966 PMC7011147__F2 Interactions between cells in the tumour microenvironment ENSG00000138798 PMC3289531__F2 A, Hepatic BCAA metabolism ENSG00000042832 ENSG00000169047 ENSG00000198793 ENSG00000062485 ENSG00000026103 PMC5938061__F7 Gastrin-CCKBR–GA12/13–RhoA–ROCK signaling in pancreatic cancer ENSG00000110148 ENSG00000026103 PMC12033294__F7 MAPK signalling pathway (KEGG:04,010, 31 counts; https://www ENSG00000087095 ENSG00000170458 ENSG00000117400 ENSG00000138798 ENSG00000130159 ENSG00000081189 ENSG00000196712 ENSG00000135517 ENSG00000026103 PMC8406585__F10 TAK1 mediates neuronal pyroptosis in early brain injury after subarachnoid hemorrhage ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC12033294__F8 cAMP signalling pathway (KEGG:04,024, 7 counts; https://www ENSG00000159224 ENSG00000069482 ENSG00000146469 ENSG00000001626 PMC7555106__F3 MDSC-mediated events in intestinal epithelial dysplasia ENSG00000143546 ENSG00000136997 ENSG00000168036 ENSG00000170989 PMC3458425__F6 Docosahexaenoic acid on mouse brain synaptic plasma membrane proteome analyzed by mass spectrometry and 16O/18O labeling ENSG00000100811 ENSG00000185518 PMC8243426__F1 Phase II study of the PI3K inhibitor copanlisib in combination with the anti-CD20 monoclonal antibody rituximab for patients with marginal zone lymphoma: treatment rationale and protocol design of the COUP-1 trial ENSG00000186716 ENSG00000198793 ENSG00000010671 PMC3861642__F9 Genes in the insulin signaling KEGG pathway that are directly or indirectly regulated by EBF1 ENSG00000104812 ENSG00000130957 ENSG00000185634 ENSG00000002330 ENSG00000169047 ENSG00000198793 ENSG00000100485 ENSG00000121879 ENSG00000180008 ENSG00000026103 ENSG00000171105 ENSG00000067057 ENSG00000044446 ENSG00000100994 ENSG00000005882 ENSG00000132356 ENSG00000076555 ENSG00000186298 ENSG00000111725 ENSG00000156873 ENSG00000181929 ENSG00000106617 ENSG00000117020 ENSG00000162409 ENSG00000133124 ENSG00000171608 ENSG00000159399 ENSG00000067177 ENSG00000152556 PMC7004076__F4 Molecular mechanisms of YQCT ENSG00000066468 ENSG00000070193 ENSG00000198793 ENSG00000166278 ENSG00000164342 PMC8659262__F1 Co-Production of Isoprene and Lactate by Engineered Escherichia coli in Microaerobic Conditions ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC7799400__F1 COVID-19 pathogenesis and MSCs role in the elimination of SARS-CoV-2 related complications (1) SARS-CoV-2 enters alveolar type II cells through binding ACE2 ENSG00000178860 ENSG00000019991 ENSG00000130234 ENSG00000001626 PMC6367542__F6 Proposed mechanisms of adiponectin-induced growth inhibition of pancreatic cancer ENSG00000168036 ENSG00000159346 ENSG00000285070 PMC1603434__F6 TSC1/TSC2 in the canonical Beta-catenin signaling pathway ENSG00000165879 ENSG00000168036 PMC6302460__F3 Comparison of four TPs in breast cancer subtypes ENSG00000002330 PMC4783948__F5 Highest-scoring and fifth highest-scoring pathway maps for the last two time points post-TBI (24 and 72 h) ENSG00000140992 ENSG00000070831 ENSG00000173039 ENSG00000145386 ENSG00000166851 ENSG00000168610 ENSG00000182541 ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000141232 ENSG00000100387 ENSG00000135446 ENSG00000149269 ENSG00000163914 ENSG00000113558 ENSG00000006451 ENSG00000123374 ENSG00000105810 ENSG00000099804 PMC4075129__F3 Molecular targets based on the predominant PI3K/AKT/GSK-3B pathway ENSG00000168036 PMC4075129__F1 PI3K/AKT/GSK-3B signaling pathway in neuronal cells of Alzheimer’s disease PMC3573419__F1 Germinal-center B-cell-like (GCB) diffuse large B-cell lymphoma (DLBCL) derived from normal germinal-center centroblasts ENSG00000153487 ENSG00000198793 ENSG00000171791 PMC4137950__F1 Human respriatory syncytial virus (hRSV) recognition by airways epithelial cells: upon infection, different hRSV components activate pattern recognition receptors (PRRs) ENSG00000169245 ENSG00000088888 ENSG00000167207 ENSG00000170458 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC7655645__F3 Protein interactions associated with signaling pathways enriched in diabetes mellitus-associated coronary heart disease ENSG00000174080 ENSG00000160299 ENSG00000291603 ENSG00000167083 ENSG00000133466 ENSG00000109956 ENSG00000168090 ENSG00000173914 ENSG00000284850 ENSG00000148798 ENSG00000187024 ENSG00000007402 ENSG00000152049 ENSG00000115419 ENSG00000158050 ENSG00000100450 ENSG00000172543 ENSG00000130638 ENSG00000005448 ENSG00000175048 ENSG00000173402 ENSG00000015676 ENSG00000087460 ENSG00000213413 ENSG00000159884 ENSG00000135631 ENSG00000105374 ENSG00000114993 ENSG00000182173 ENSG00000067840 ENSG00000065029 ENSG00000178028 ENSG00000165688 ENSG00000170779 PMC2727431__F1 Various states of pluripotency ENSG00000128342 ENSG00000136826 PMC4524600__F6 Comparative Transcriptome Analysis of Differentially Expressed Genes and Signaling Pathways between XY and YY Testis in Yellow Catfish ENSG00000112964 ENSG00000004948 ENSG00000102539 ENSG00000180616 ENSG00000170498 ENSG00000168398 ENSG00000285456 ENSG00000113494 PMC6277997__F6 Mechanisms of DMTN in the invasion and metastasis of CRC ENSG00000158856 ENSG00000149269 ENSG00000116584 PMC4524600__F5 Comparative Transcriptome Analysis of Differentially Expressed Genes and Signaling Pathways between XY and YY Testis in Yellow Catfish ENSG00000177455 ENSG00000182578 ENSG00000049130 ENSG00000105401 ENSG00000186716 ENSG00000136869 PMC4414328__F8 We propose three possible pathways that could lead to liver NKT cell anergy ENSG00000154342 ENSG00000168036 PMC3573419__F2 Activated B-cell-like (ABC) diffuse large B-cell lymphomas (DLBCLs) are derived from plasmablasts that are characterized by a block in differentiation ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000198793 ENSG00000172936 ENSG00000269404 ENSG00000171791 ENSG00000168610 ENSG00000131196 ENSG00000010671 ENSG00000198286 PMC8159877__F4 Changes associated with IMR in the anterior leaflets at 4 weeks post-MI within the TGFB signaling pathway ENSG00000170365 ENSG00000137834 ENSG00000111537 ENSG00000095739 ENSG00000175104 PMC4720912__F2 Insulin signaling pathway ENSG00000171105 ENSG00000002330 PMC4945843__F1 Major cholesterol metabolism pathways in the liver ENSG00000130164 ENSG00000167910 ENSG00000113161 ENSG00000169710 ENSG00000160179 PMC9444456__F2 Translocator Protein 18 kDa (TSPO) as a Novel Therapeutic Target for Chronic Pain ENSG00000163739 PMC11641026__F4 Biosynthesis of aminonucleosides ENSG00000121552 PMC4325931__F6 Overlay of gene expression on the p53 signaling pathway ENSG00000175793 ENSG00000135446 ENSG00000112378 ENSG00000120868 ENSG00000026103 PMC5088662__F5 Schematic diagram elucidating signalling pathway of TLR4 and TLR9 responsible for GFNs-induced cytotoxicity ENSG00000239732 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC8549894__F2 Pathophysiology of Exercise-Induced Muscle Damage and Its Structural, Functional, Metabolic, and Clinical Consequences ENSG00000115020 PMC5350147__F1 Akt/mTOR signaling schematic ENSG00000169047 ENSG00000198793 ENSG00000196712 PMC9314012__F2 Periodontitis, chronic liver diseases, and the emerging oral‐gut‐liver axis ENSG00000125538 ENSG00000169047 ENSG00000172936 ENSG00000136869 PMC6617469__F4 Expressional change of genes for the central carbon metabolic network in Kmmig1 ENSG00000240303 ENSG00000172955 ENSG00000175097 ENSG00000146701 PMC3540890__F1 Biosynthetic pathway of prostaglandins PMC5335622__F2 Theoretical concept of combined application of checkpoint blockade therapy and DGK-inhibition ENSG00000291603 ENSG00000111537 PMC3084054__F1 Synthesis-enabled functional group deletions to probe predicted intermolecular interactions involving the C41 carboxylic acid and/or the C19 mycosamine appendages of AmB ENSG00000213626 PMC3822825__F2 E2F1-induced apoptosis ENSG00000149311 ENSG00000175054 ENSG00000120868 PMC6885770__F1 Nrf2/HO-1 pathway ENSG00000178573 ENSG00000100387 ENSG00000079999 PMC8843872__F1 Ferroptosis: An emerging therapeutic opportunity for cancer ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000111684 PMC5088662__F4 MAPKs, TGF-beta and TNFA dependent pathways involved in GFNs toxicity PMC4925704__F2 Anti-Cancer Properties of the Naturally Occurring Aphrodisiacs: Icariin and Its Derivatives ENSG00000168036 ENSG00000168040 ENSG00000168610 ENSG00000146648 ENSG00000026103 PMC3069932__F9 Proposed role of Nodal in human placental development and mechanism of Nodal-regulated trophoblast invasion ENSG00000087245 ENSG00000156574 PMC3836323__F2 Vascular smooth muscle cells mechanotransduction mechanisms in stretch-dependent interconnected signalling PMC4268999__F2 PI3K/Akt signalling pathway ENSG00000002330 ENSG00000198793 ENSG00000171791 PMC4268999__F1 Wnt/Beta-catenin pathway ENSG00000281324 ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000167074 PMC10958678__F7 P53 and mut‐p53 in the TME during cancer development ENSG00000131015 ENSG00000187608 PMC4461458__F2 Prevalent mutations in acute myeloid leukemia (AML) potentially affect HIF levels in cancer cells ENSG00000134086 ENSG00000198793 PMC10958678__F6 Functional activities of mut‐p53 in cancers ENSG00000107562 ENSG00000185022 ENSG00000151012 ENSG00000159388 ENSG00000100697 ENSG00000205250 ENSG00000167900 ENSG00000164305 ENSG00000196628 ENSG00000012048 ENSG00000157557 ENSG00000160973 ENSG00000128272 ENSG00000171872 ENSG00000132646 ENSG00000150907 ENSG00000026508 ENSG00000146648 ENSG00000140464 ENSG00000175305 PMC6682527__F4 KLF5-targeted genes in the pancreatic cancer pathway ENSG00000017797 ENSG00000002330 ENSG00000112242 ENSG00000163235 ENSG00000138798 ENSG00000198793 ENSG00000051180 ENSG00000168610 ENSG00000146648 ENSG00000282899 ENSG00000122008 ENSG00000139618 PMC9514046__F2 Interleukin 22 and its association with neurodegenerative disease activity ENSG00000186810 ENSG00000184451 ENSG00000128342 ENSG00000112486 PMC8685420__F3 Identification and Characterization of Key Differentially Expressed Genes Associated With Metronomic Dosing of Topotecan in Human Prostate Cancer ENSG00000169896 ENSG00000011422 ENSG00000109320 ENSG00000177606 ENSG00000171791 ENSG00000091879 ENSG00000112715 ENSG00000124762 ENSG00000137801 PMC5987683__F3 Mitogen-activated protein kinase signalling pathway ENSG00000087095 ENSG00000172680 ENSG00000157764 ENSG00000109320 ENSG00000138798 ENSG00000130159 ENSG00000127191 ENSG00000081189 ENSG00000128272 ENSG00000170458 ENSG00000177606 ENSG00000136997 ENSG00000175104 ENSG00000026103 PMC7526126__F3 InterferonG mediated cancer regression ENSG00000168003 ENSG00000132906 ENSG00000151012 ENSG00000163064 ENSG00000112715 ENSG00000064012 ENSG00000164305 PMC7399975__F6 Tec kinase signaling and FAT10 pathway ENSG00000291971 ENSG00000168040 ENSG00000135605 ENSG00000010671 ENSG00000186469 PMC7526126__F1 InterferonG signaling ENSG00000115415 ENSG00000198793 ENSG00000125347 PMC8557551__F6 Synergistic stimulation of osteoblast differentiation of rat mesenchymal stem cells by leptin and 25(OH)D3 is mediated by inhibition of chaperone-mediated autophagy ENSG00000111012 ENSG00000108821 PMC3179548__F2 PE intoxication pathway ENSG00000140564 ENSG00000168702 ENSG00000167658 PMC8909190__F2 Transcriptomics Reveals Discordant Lipid Metabolism Effects between In Vitro Models Exposed to Elafibranor and Liver Samples of NAFLD Patients after Bariatric Surgery ENSG00000142192 ENSG00000069482 ENSG00000119912 PMC7748976__F1 Interaction of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) virus with the renin-angiotensin system and phagocyte activation cascade ENSG00000130234 PMC4811771__F16 SLE risk haplotype upregulates the antigen presentation pathway (APP) ENSG00000136250 ENSG00000166478 ENSG00000124226 ENSG00000284099 ENSG00000137265 ENSG00000123810 ENSG00000281877 ENSG00000166278 ENSG00000107874 ENSG00000169871 PMC9249764__F4 Effect of VEN incubation on gene expression of apoptotic signaling cascades in SEM (upper panel) and RS4;11 cells (lower panel) ENSG00000110330 ENSG00000002330 ENSG00000153094 ENSG00000102871 ENSG00000095015 ENSG00000119969 ENSG00000171791 ENSG00000146072 ENSG00000136997 ENSG00000137265 ENSG00000168310 ENSG00000140443 ENSG00000026103 ENSG00000104365 ENSG00000100906 ENSG00000109320 ENSG00000269335 ENSG00000173039 ENSG00000065559 ENSG00000213341 ENSG00000168040 ENSG00000127191 ENSG00000276561 ENSG00000215788 ENSG00000226275 ENSG00000144857 ENSG00000258643 PMC8609049__F1 “Aerobic glycolytic imaging” of human gliomas using combined pH-, oxygen-, and perfusion-weighted magnetic resonance imaging ENSG00000213658 ENSG00000198793 ENSG00000115419 ENSG00000159399 ENSG00000116984 PMC2600878__F6 Syk signaling is necessary for E-selectin-induced LFA-1-ICAM-1 association and rolling but not arrest ENSG00000163739 PMC2843172__F8 Schematic drawing summarizing the signaling pathway downstream from CB1 receptors in cerebellar granule cell precursors ENSG00000168036 PMC12121766__F2 Sites of activity of genes encoded by SNPs observed to be associated in our study in the NO signaling pathway downstream of Cit ENSG00000135643 ENSG00000198890 PMC4963810__F2 Comparison of the Drosophila and vertebrate non-canonical Wnt pathways applicable to this proposal ENSG00000162552 ENSG00000171444 ENSG00000111186 PMC4546915__F1 Adaptive stress signaling in targeted therapy resistance in cancer ENSG00000140992 ENSG00000183735 ENSG00000002330 ENSG00000070831 ENSG00000006451 ENSG00000144118 ENSG00000169047 ENSG00000136111 PMC2922838__F2 Gene expression profiling in whole blood of patients with coronary artery disease ENSG00000119013 ENSG00000164305 ENSG00000084774 PMC7137347__F1 LncRNA in regulating stem cell pluripotency ENSG00000156574 ENSG00000077463 PMC5460107__F2 FLT3 signaling pathway ENSG00000122025 ENSG00000198793 PMC5247290__F3 TGF-b/BMP signaling pathway in osteoblast differentiation ENSG00000170365 PMC4415606__F4 Arginine deiminase (ADI) hydrolyzes arginine into citrulline ENSG00000198793 PMC5247290__F2 Canonical Wnt/b-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC12205714__F8 The potential protective mechanism of BJOE in irinotecan-induced delayed diarrhea mice ENSG00000183735 ENSG00000164430 PMC11354818__F12 Integrative Analyses Reveal the Physiological and Molecular Role of Prohexadione Calcium in Regulating Salt Tolerance in Rice ENSG00000110934 ENSG00000221818 ENSG00000138443 PMC11354818__F14 Integrative Analyses Reveal the Physiological and Molecular Role of Prohexadione Calcium in Regulating Salt Tolerance in Rice ENSG00000140505 ENSG00000130649 PMC8582658__F1 Key Role of the WNT/Beta-Catenin Pathway in Metabolic Reprogramming in Cancers under Normoxic Conditions ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3736482__F3 Associated intracellular cascades to physiopathology of vascular remodeling ENSG00000291971 ENSG00000162692 ENSG00000146648 PMC8872751__F6 Transcriptome analysis reveals transforming growth factorB1 prevents extracellular matrix degradation and cell adhesion during the follicular-luteal transition in cows ENSG00000149564 ENSG00000115884 ENSG00000105329 ENSG00000138798 ENSG00000108821 PMC8817718__F3 Damage-Associated Molecular Patterns As Double-Edged Swords in Sepsis ENSG00000162711 ENSG00000239732 ENSG00000136869 PMC8817718__F2 Damage-Associated Molecular Patterns As Double-Edged Swords in Sepsis ENSG00000162711 ENSG00000172936 ENSG00000168610 PMC8724844__F7A Cellular RhoA Functions by the Integrated Application of Gene Set Enrichment Analysis ENSG00000135604 ENSG00000135823 ENSG00000168818 ENSG00000111450 ENSG00000099940 ENSG00000118640 ENSG00000136874 ENSG00000292366 ENSG00000053501 ENSG00000170310 ENSG00000220205 ENSG00000079950 ENSG00000139190 PMC6887687__F1 Main signalling pathways of programmed necrosis in cardiomyocytes ENSG00000102871 ENSG00000133116 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 PMC2844426__F4 Mutations in CHMP2B in Lower Motor Neuron Predominant Amyotrophic Lateral Sclerosis (ALS) ENSG00000196712 PMC8582658__F6 Key Role of the WNT/Beta-Catenin Pathway in Metabolic Reprogramming in Cancers under Normoxic Conditions ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8582658__F5 Key Role of the WNT/Beta-Catenin Pathway in Metabolic Reprogramming in Cancers under Normoxic Conditions ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8582658__F3 Key Role of the WNT/Beta-Catenin Pathway in Metabolic Reprogramming in Cancers under Normoxic Conditions ENSG00000281324 ENSG00000162337 ENSG00000005882 ENSG00000168036 ENSG00000168610 PMC8582658__F2 Key Role of the WNT/Beta-Catenin Pathway in Metabolic Reprogramming in Cancers under Normoxic Conditions ENSG00000127445 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5341220__F2 Canonical signalling pathways activated by the EP receptors ENSG00000168036 PMC5516996__F3 Heterogeneity of p53 dependent genomic responses following ethanol exposure in a developmental mouse model of fetal alcohol spectrum disorder ENSG00000149311 ENSG00000175054 ENSG00000136997 ENSG00000123374 ENSG00000112378 ENSG00000196470 ENSG00000026103 PMC5516996__F5 Heterogeneity of p53 dependent genomic responses following ethanol exposure in a developmental mouse model of fetal alcohol spectrum disorder ENSG00000145604 ENSG00000108055 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000205250 ENSG00000091651 ENSG00000277273 ENSG00000117399 ENSG00000276876 ENSG00000093009 PMC4266525__F1 Pathway for corticosteroid synthesis in the human adrenal gland ENSG00000203859 ENSG00000179142 ENSG00000176387 PMC11522771__F2 Signaling pathways involved in cardiac fibrosis ENSG00000137834 ENSG00000198742 ENSG00000198732 PMC2852570__F1 Semaphorin signaling ENSG00000163914 PMC8615192__F5 Transcriptomic Profile of New Gene Markers Encoding Proteins Responsible for Structure of Porcine Ovarian Granulosa Cells ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000069482 ENSG00000186716 ENSG00000197601 PMC8615192__F4 Transcriptomic Profile of New Gene Markers Encoding Proteins Responsible for Structure of Porcine Ovarian Granulosa Cells ENSG00000169291 ENSG00000002330 ENSG00000177606 PMC8615192__F7 Transcriptomic Profile of New Gene Markers Encoding Proteins Responsible for Structure of Porcine Ovarian Granulosa Cells ENSG00000213658 ENSG00000171540 ENSG00000115718 ENSG00000084774 PMC8615192__F6 Transcriptomic Profile of New Gene Markers Encoding Proteins Responsible for Structure of Porcine Ovarian Granulosa Cells ENSG00000145604 ENSG00000149311 ENSG00000087095 ENSG00000171105 ENSG00000179091 ENSG00000127528 ENSG00000123374 ENSG00000166278 ENSG00000145782 PMC4644734__F1 Steps in the macroautophagy pathway ENSG00000177169 ENSG00000126775 ENSG00000198793 PMC3617041__F6 TGFB restoration by SMAD6 knockdown ENSG00000137834 PMC7056928__F4 Cholesterol auxotrophic lymphomas accumulate squalene, an antioxidant-like metabolite ENSG00000130164 ENSG00000151012 ENSG00000167468 ENSG00000104549 ENSG00000115419 PMC8444957__F1 Advances in research on pharmacotherapy of sarcopenia ENSG00000291971 ENSG00000130234 ENSG00000198793 ENSG00000134363 PMC1601946__F1 E3 ubiquitin ligases regulating the TGFB signaling pathway ENSG00000078747 ENSG00000134982 ENSG00000198742 ENSG00000123124 PMC8615192__F1 Transcriptomic Profile of New Gene Markers Encoding Proteins Responsible for Structure of Porcine Ovarian Granulosa Cells ENSG00000137834 ENSG00000095739 ENSG00000187720 ENSG00000100387 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000205250 ENSG00000137801 PMC8615192__F3 Transcriptomic Profile of New Gene Markers Encoding Proteins Responsible for Structure of Porcine Ovarian Granulosa Cells ENSG00000124102 ENSG00000118007 ENSG00000108055 ENSG00000112118 ENSG00000205250 ENSG00000073111 ENSG00000277273 ENSG00000093009 ENSG00000145604 ENSG00000101972 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000164754 PMC8685420__F8 Identification and Characterization of Key Differentially Expressed Genes Associated With Metronomic Dosing of Topotecan in Human Prostate Cancer ENSG00000206075 ENSG00000163914 ENSG00000122194 PMC8615192__F2 Transcriptomic Profile of New Gene Markers Encoding Proteins Responsible for Structure of Porcine Ovarian Granulosa Cells ENSG00000136457 ENSG00000135218 ENSG00000110799 ENSG00000026508 ENSG00000152592 PMC9335949__F7 Explore the Potential Ingredients for Detoxification of Honey-Fired Licorice (ZGC) Based on the Metabolic Profile by UPLC-Q-TOF-MS ENSG00000277897 PMC11662066__SF3 Clinical pathway, Cohort II ENSG00000156026 ENSG00000132693 PMC3292309__F3 Activation of inflammatory mediators in pancreatic Beta-cells in type 1 diabetes ENSG00000150782 ENSG00000115415 ENSG00000102871 ENSG00000172936 ENSG00000127191 PMC8940899__F7 MiR-323a-3p inhibits gefitinib resistance acquisition by targeting ErbB3/PI3K/Akt-EGFR/Erk1/2 signaling in colorectal cancer ENSG00000065361 ENSG00000146648 PMC2850427__F2 Simplified Overview of the Purine Metabolism PathwayThe scheme is derived from KEGG Pathways hsa00230 (purine metabolism) and hsa00240 (pyrimidine metabolism) ENSG00000196839 ENSG00000291814 PMC5673628__F12 Schematic summary of baicalin-driven regulation of autophagy and inflammation during Mtb infection ENSG00000162711 ENSG00000198793 PMC10388552__F6 Aberrations in ion channels interacting with lipid metabolism and epithelial–mesenchymal transition in esophageal squamous cell carcinoma ENSG00000171105 ENSG00000099985 ENSG00000128342 ENSG00000146648 ENSG00000197461 PMC7960610__F2 Schematic presentation of common molecular genetic aberrancies in parathyroid adenoma (PA; left) and carcinoma (PC; right) ENSG00000134982 ENSG00000130522 ENSG00000168036 PMC2879972__F4 Illustration of different mechanisms of MUC1 and MUC4 for the repression of apoptosis ENSG00000168040 ENSG00000145113 PMC8216764__F1 Potential Role for Integrin-Linked Kinase in Colorectal Cancer Growth and Progression via Regulating Senescence and Immunity ENSG00000132323 ENSG00000291971 ENSG00000164327 ENSG00000071051 ENSG00000136869 ENSG00000105370 PMC3412266__F1 Atypical PKC signaling pathways leading to lymphocyte activation and/or differentiation ENSG00000186716 ENSG00000173039 ENSG00000175104 ENSG00000131196 PMC1891745__F1 Diagram illustrating Functional JAK STAT PathwayThis “JAK STAT” pathway appears to be ubiquitous amongst vertebrates PMC5120225__F2 Signaling pathway of liver fibrogenisisThe injured liver produces various cell factors, which can activate transforming growth factor beta (TGFB) and platelet-derived growth factor beta (PDGFB), and bone morphogenetic protein (BMP) PMC3584306__F3 Obesity Pharmacotherapy: Current Perspectives and Future Directions ENSG00000198576 ENSG00000112246 ENSG00000170893 ENSG00000166603 PMC5812347__F2 Biochemical, Cell Biological, Pathological, and Therapeutic Aspects of Krabbe Disease PMC2742785__F8 Cluster 2 genes significantly overlapped with those in the eicosanoid signaling pathway (P = 4.6E-05) ENSG00000179477 ENSG00000158786 ENSG00000188784 ENSG00000100577 ENSG00000100078 ENSG00000182621 ENSG00000073756 ENSG00000285456 ENSG00000127472 ENSG00000187980 PMC2607021__F4 Genome-Wide Association Study Identifies Novel and Functionally Related Susceptibility Loci for Kawasaki Disease ENSG00000070193 ENSG00000152495 ENSG00000139517 ENSG00000133961 ENSG00000145349 ENSG00000072201 PMC5558921__F2 BER pathway is essential in the nervous system ENSG00000105486 ENSG00000132646 ENSG00000039650 ENSG00000177084 ENSG00000042088 PMC11900433__F11 Unfolded protein response (UPR) pathway ENSG00000128272 ENSG00000100219 ENSG00000127191 PMC8678597__F1 Crosstalk Between Autophagy and the cGAS–STING Signaling Pathway in Type I Interferon Production ENSG00000183735 ENSG00000164430 PMC7435717__F5 Effect of Icariin, Purmorphamine, U0126, and PD98059 on osteogenic signaling pathways ENSG00000242252 ENSG00000168036 ENSG00000128602 PMC10376516__F4 Recent Advances in Nanomaterials-Based Targeted Drug Delivery for Preclinical Cancer Diagnosis and Therapeutics ENSG00000198793 PMC6991638__F7 Inhibitory effect of WKYMVm on osteoclast formation and bone resorption activity ENSG00000171049 ENSG00000010278 ENSG00000168610 PMC8120466__F6 MUC3A induces PD-L1 and reduces tyrosine kinase inhibitors effects in EGFR-mutant non-small cell lung cancer ENSG00000138798 ENSG00000146648 PMC8902048__F1 Rotenone Modulates Caenorhabditis elegans Immunometabolism and Pathogen Susceptibility ENSG00000169136 ENSG00000198793 ENSG00000170653 PMC4051228__F1 The folate/Hcy metabolic pathway ENSG00000228716 ENSG00000124275 ENSG00000035928 ENSG00000116984 PMC5734931__F2 Formation of autophagasomes in autophagy ENSG00000177169 ENSG00000152348 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC4622843__F4 Interaction network of differentially methylated diabetic genes ENSG00000053747 ENSG00000105329 ENSG00000138798 ENSG00000197632 ENSG00000136997 ENSG00000134871 ENSG00000166147 PMC5065302__F6 Mechanisms through which rolipram (ROL) attenuates pain behavior in bone cancer pain ENSG00000108691 ENSG00000125538 ENSG00000121807 PMC5920380__F1 Molecular mechanisms of suppressor of fused in regulating the hedgehog signalling pathway ENSG00000106571 ENSG00000166813 ENSG00000121067 ENSG00000128602 PMC4348071__F1 Exploiting the head and neck cancer oncogenome: Widespread PI3K-mTOR pathway alterations and novel molecular targets ENSG00000083857 ENSG00000175634 ENSG00000148400 ENSG00000198793 ENSG00000164327 ENSG00000133961 ENSG00000121879 ENSG00000146648 PMC3669657__F6 Observed effects of Hedgehog and Wnt inhibition, and Sox17 overexpression in HOG cells ENSG00000281324 ENSG00000164736 ENSG00000162337 ENSG00000168036 ENSG00000164690 ENSG00000139549 ENSG00000104332 ENSG00000128602 ENSG00000163501 ENSG00000196628 PMC3310485__F4 Schematic of the role of BDNF in the brain reward pathway associated with addiction PMC3408604__F1 Cardiac myocyte signaling coupled to phosphodiesterase (PDE) 5 ENSG00000285109 ENSG00000137672 PMC9136126__F6 Gut microbiota-derived metabolites contribute negatively to hindgut barrier function development at the early weaning goat model ENSG00000131142 ENSG00000140284 ENSG00000170231 PMC4526101__F3 The type I diabetes mellitus pathway in which HLA-A, HLA-B, HLA-C, HLA-DPB1 and GAD1 are involved ENSG00000111537 ENSG00000180644 ENSG00000026103 PMC3390457__F1 Neuroprotective signaling pathways employed by Erythropoietin ENSG00000187266 PMC3514635__F4 Intracellular trafficking proteins involved in CMT neuropathy ENSG00000112367 ENSG00000116688 ENSG00000087053 ENSG00000122877 ENSG00000104381 ENSG00000158887 PMC4526101__F2 The systemic lupus erythematosus pathway in which HLA-DPB1, HIST1H4J, HIST1H2BO, H3F3C, H2AFY, H3F3A, HIST2H3D, HIST1H4D, HIST2H4B, HIST1H2BL and HIST1H4K are involved ENSG00000205323 ENSG00000134982 ENSG00000186716 ENSG00000172005 ENSG00000166278 ENSG00000062485 PMC11058998__F4 Pleiotropic physiological functions of Piezo1 in human body and its effect on malignant behavior of tumors ENSG00000156026 ENSG00000198793 ENSG00000150457 ENSG00000131023 ENSG00000108774 PMC11058998__F3 Piezo1 affects the occurrence and development of diseases through multiple signaling pathways ENSG00000162711 ENSG00000198793 ENSG00000103335 PMC2287275__F2 Mesenchymal stem cell dysfunction in HGPS ENSG00000178860 ENSG00000135547 ENSG00000173673 ENSG00000273529 ENSG00000114315 PMC6651655__F3 Representation of S100B effects on Caco-2 cells ENSG00000198793 ENSG00000105656 PMC11854313__F2 Biosynthetic pathway of terpenoids ENSG00000110921 ENSG00000197429 PMC7256186__F1 Warburg effect in melanoma cells caused by BRAFV600E mutation leading to constitutive activation of MAPK pathway ENSG00000074800 ENSG00000136997 ENSG00000159399 PMC7513299__F1 Adipocytes in EOC metastasis ENSG00000019991 ENSG00000026508 PMC11612565__F4 Mechanisms of EC pyroptosis in sepsis ENSG00000278718 ENSG00000162711 ENSG00000285176 ENSG00000164430 ENSG00000137033 ENSG00000189403 ENSG00000136869 PMC11612565__F3 Specific pathophysiological mechanisms of EC apoptosis in sepsis ENSG00000120742 ENSG00000145147 ENSG00000198793 ENSG00000137193 ENSG00000084112 ENSG00000067900 ENSG00000253352 ENSG00000118257 ENSG00000168610 PMC11612565__F6 Relationship of EC autophagy and function and EC autophagy-related mechanisms in sepsis ENSG00000145604 ENSG00000019582 ENSG00000162711 ENSG00000011304 ENSG00000105835 ENSG00000198793 ENSG00000096717 PMC11612565__F5 Mechanisms related to ferroptosis of ECs in sepsis ENSG00000115884 ENSG00000167468 ENSG00000086991 ENSG00000164647 ENSG00000135414 ENSG00000073792 ENSG00000162772 ENSG00000096717 ENSG00000079999 PMC10865661__F15 Apium extract alleviates indomethacin-induced gastric ulcers in rats via modulating the VEGF and IKKB/NFKB p65 signaling pathway: insights from in silico and in vivo investigations ENSG00000002330 ENSG00000070831 PMC8088756__F2 Demyelination as a result of an immune response in patients with COVID-19 ENSG00000170458 ENSG00000172936 PMC4445098__F6 Network between MAPK signaling pathway-related genes and miRNAs ENSG00000149930 ENSG00000105329 ENSG00000141480 ENSG00000167535 ENSG00000067191 ENSG00000006062 ENSG00000139625 ENSG00000126458 ENSG00000136068 PMC5387690__F7 A Caenorhabditis elegans Genome-Scale Metabolic Network Model ENSG00000144063 PMC9227929__F2 Interactions between Tryptophan Metabolism, the Gut Microbiome and the Immune System as Potential Drivers of Non-Alcoholic Fatty Liver Disease (NAFLD) and Metabolic Diseases ENSG00000188676 PMC8447597__EV3 Drugs targeting SARS‐CoV‐2 and host protein interaction ENSG00000110700 ENSG00000228716 ENSG00000291931 ENSG00000110921 ENSG00000182774 ENSG00000099624 ENSG00000061918 ENSG00000170558 ENSG00000146143 ENSG00000198056 ENSG00000206075 ENSG00000101868 ENSG00000292234 ENSG00000113558 ENSG00000147955 ENSG00000220205 ENSG00000014138 ENSG00000037280 ENSG00000120265 ENSG00000107779 ENSG00000108298 ENSG00000197081 ENSG00000140263 ENSG00000198242 ENSG00000278270 ENSG00000215021 ENSG00000037241 ENSG00000117020 ENSG00000241837 ENSG00000161634 ENSG00000175899 ENSG00000146648 ENSG00000178568 PMC9694790__F2 Advances in Fucoxanthin Research for the Prevention and Treatment of Inflammation-Related Diseases ENSG00000125538 ENSG00000172936 ENSG00000175104 PMC9694790__F4 Advances in Fucoxanthin Research for the Prevention and Treatment of Inflammation-Related Diseases ENSG00000135446 ENSG00000123374 ENSG00000116717 ENSG00000105810 ENSG00000171791 PMC8197962__F1 ZNF-281 as the Potential Diagnostic Marker of Oral Squamous Cell Carcinoma ENSG00000124766 ENSG00000168036 ENSG00000100985 PMC7345850__F9 Left panel: Balanced autophagic flux ENSG00000003056 ENSG00000284099 PMC11612565__F2 Effect of DAMPs on vascular ECs during sepsis or severe bacterial infections ENSG00000162711 ENSG00000189403 PMC8958883__F1 Wnt/Beta-catenin signaling pathway in the tumor microenvironment of hepatocellular carcinoma ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6907065__F2 The mechanism of UVA-modulated HO-1 regulation through the PERK and Nrf2 signal pathway ENSG00000128272 ENSG00000144895 ENSG00000079999 PMC8944161__F1 Clinical benefits of PD-1/PD-L1 inhibitors in patients with metastatic colorectal cancer: a systematic review and meta-analysis ENSG00000291603 ENSG00000213658 ENSG00000134982 PMC11671274__F1 Intestinal changes in T2DM ENSG00000111537 ENSG00000125538 ENSG00000172936 ENSG00000131096 PMC4773818__F6 Pharmacoproteomic analysis reveals that metapristone (RU486 metabolite) intervenes E-cadherin and vimentin to realize cancer metastasis chemoprevention PMC5790278__F7 Molecular mechanism of inhibitory effects of bovine lactoferrin on the growth of oral squamous cell carcinoma ENSG00000198793 ENSG00000168610 PMC7708728__F1 Systematic Review of the Kynurenine Pathway and Psychoneurological Symptoms Among Adult Cancer Survivors ENSG00000132693 PMC6086625__F5 Kinases associated with the CX3CL1/CX3CR1 axis ENSG00000259207 ENSG00000120899 ENSG00000291971 ENSG00000146648 PMC11513491__F3 Schematic illustration proposed for the probable role of PI3K axis in AML cells ENSG00000198793 PMC4151374__F2 Interaction network using Pathway studio ENSG00000053747 ENSG00000143952 ENSG00000203772 ENSG00000164344 ENSG00000122194 PMC4151374__F1 Biological network inferences for a protection mechanism against familial Creutzfeldt-Jakob disease with E200K pathogenic mutation ENSG00000053747 ENSG00000110076 ENSG00000164344 ENSG00000122194 PMC4334309__F2 Directed evolution of the nonribosomal peptide synthetase AdmK.Notes: Andrimid is biosynthesized by a hybrid nonribosomal peptide synthetase/polyketide synthase pathway ENSG00000042832 ENSG00000148926 PMC7836194__F2 Curcumin mediates miRNA regulation in PC ENSG00000088305 ENSG00000135446 ENSG00000187140 ENSG00000066739 ENSG00000168036 PMC3875780__F3 Human intestinal innate myeloid cells ENSG00000170458 ENSG00000187554 ENSG00000137265 ENSG00000136869 PMC6315509__F1 Notch and Wnt signaling pathways ENSG00000281324 ENSG00000162337 PMC7356262__F8 Canonical pathway “Osteoarthritis Signaling” for Epi C vs ENSG00000188786 ENSG00000100234 ENSG00000105835 ENSG00000171720 ENSG00000168214 ENSG00000291837 ENSG00000189403 ENSG00000185591 ENSG00000166670 ENSG00000100985 ENSG00000114315 PMC7356262__F7 Canonical pathway “NF-kB Signaling” for VA vs ENSG00000104856 ENSG00000102871 ENSG00000138798 ENSG00000173039 ENSG00000162924 ENSG00000168040 ENSG00000150455 ENSG00000226275 ENSG00000244687 ENSG00000163235 ENSG00000197943 ENSG00000157625 ENSG00000172936 PMC4661887__F4 Mechanism of action of soy peptides in HepG2 cells ENSG00000130164 ENSG00000198793 ENSG00000164327 PMC7356262__F6 Canonical pathway “Osteoarthritis Signaling” for VA vs ENSG00000139219 ENSG00000105835 ENSG00000125398 ENSG00000171720 ENSG00000291837 ENSG00000168036 ENSG00000189403 ENSG00000185591 ENSG00000166670 PMC3461959__F3 Blastocyst Lineage Segregation and Stem Cells ENSG00000164736 ENSG00000141448 ENSG00000285109 PMC4465084__F1 Investigational approaches targeting the factors contributing to celiac disease pathogenesis ENSG00000134982 ENSG00000231179 ENSG00000204520 PMC9097215__F2 Tumor Suppressor Kinase LKB1: Metabolic Nexus ENSG00000074800 ENSG00000159399 PMC8064323__F10 Gene clusters annotated to drug addiction pathways in HIV+ prefrontal cortex and the effect of Meth use ENSG00000130643 ENSG00000198785 ENSG00000086065 ENSG00000102001 ENSG00000112038 ENSG00000151834 ENSG00000148408 ENSG00000180879 ENSG00000152208 ENSG00000120251 ENSG00000165646 ENSG00000173406 ENSG00000163873 ENSG00000157542 ENSG00000189056 ENSG00000143578 ENSG00000102468 ENSG00000132518 ENSG00000164742 ENSG00000197576 ENSG00000139287 ENSG00000105737 ENSG00000125675 ENSG00000112640 ENSG00000162104 ENSG00000125740 ENSG00000065989 ENSG00000157193 ENSG00000184845 ENSG00000129167 ENSG00000197283 ENSG00000132535 ENSG00000171189 ENSG00000011677 ENSG00000081248 ENSG00000178363 ENSG00000127022 ENSG00000164082 ENSG00000163285 ENSG00000182256 ENSG00000123360 ENSG00000102287 ENSG00000176884 ENSG00000174233 ENSG00000113327 ENSG00000154678 ENSG00000171759 ENSG00000145349 ENSG00000171408 PMC7867092__F2 Leptin-promoted lipid metabolic reprogramming in cancer cells ENSG00000135218 ENSG00000168610 PMC3707630__F7 CD44 Is the Signaling Component of the Macrophage Migration Inhibitory Factor-CD74 Receptor Complex ENSG00000019582 ENSG00000291971 ENSG00000163914 ENSG00000026508 PMC9133699__F9 Reconstruction of a Genome-Scale Metabolic Network for Shewanella oneidensis MR-1 and Analysis of its Metabolic Potential for Bioelectrochemical Systems ENSG00000134982 ENSG00000172005 PMC8380940__F1 Engineering Biological Electron Transfer and Redox Pathways for Nanoparticle Synthesis PMC6506734__F1 Downstream signaling pathway of adiponectin ENSG00000157500 ENSG00000185591 PMC6952810__F2 MicroRNAs regulating key genes of the TGFB signaling pathway PMC5085112__F7 Organochloride pesticides induced hepatic ABCG5/G8 expression and lipogenesis in Chinese patients with gallstone disease ENSG00000005471 ENSG00000138075 ENSG00000130164 ENSG00000113161 ENSG00000073734 ENSG00000026103 PMC5364554__F9 Acceleration of bone regeneration by activating Wnt/Beta-catenin signalling pathway via lithium released from lithium chloride/calcium phosphate cement in osteoporosis ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000165879 ENSG00000168036 PMC6291520__F6 Graphical summary ENSG00000198793 ENSG00000057663 PMC5962649__F4 Historic and updated model of IRS signaling ENSG00000044090 ENSG00000182511 ENSG00000033327 ENSG00000106070 ENSG00000169047 ENSG00000164327 ENSG00000102104 ENSG00000106546 PMC12137631__F4 Molecular mapping of HFD-induced liver inflammation and metabolic dysregulation HFD induced liver steatosis through activating key inflammatory and lipid metabolism genes ENSG00000171105 ENSG00000161921 ENSG00000109320 ENSG00000169047 ENSG00000160179 ENSG00000099194 ENSG00000121879 ENSG00000132170 PMC5463358__F3 Microglial M1 and M2 signaling in neurodegeneration, and potential targets for neuroprotection ENSG00000108691 ENSG00000159128 ENSG00000111537 ENSG00000105397 ENSG00000170458 ENSG00000115415 ENSG00000189403 ENSG00000027697 ENSG00000172936 ENSG00000136869 ENSG00000118520 ENSG00000105639 PMC3296080__F1 Interactions between insulin-like growth factor-1 receptor (IGF-1R), insulin receptor (IR), and epidermal growth factor receptor (EGFR) signaling pathways ENSG00000002330 ENSG00000197081 ENSG00000005882 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC12137631__F3 High fat diet disrupts Insulin signalling Pathway ENSG00000171105 ENSG00000169047 ENSG00000121879 ENSG00000196396 PMC2241839__F3 Cholesterol biosynthesis pathway ENSG00000110921 ENSG00000172893 ENSG00000113161 ENSG00000166278 ENSG00000120437 ENSG00000167508 ENSG00000160752 ENSG00000132196 ENSG00000116133 ENSG00000152904 ENSG00000109929 ENSG00000149809 ENSG00000104549 PMC8407594__F1 Combined overview of all qualitative Wnt (sub-)models found within the 19 Wnt simulation studies ENSG00000281324 ENSG00000164736 ENSG00000134982 ENSG00000138798 ENSG00000179111 ENSG00000168646 ENSG00000146648 ENSG00000106003 ENSG00000140807 PMC6297716__F4 Scheme illustrating the signaling pathways and transcription factors contributing to SND1 promoter activation ENSG00000185591 ENSG00000100219 PMC5354998__F10 Integrated genomic and molecular characterization of cervical cancer ENSG00000167601 ENSG00000087510 ENSG00000100234 ENSG00000152661 ENSG00000140564 ENSG00000002330 ENSG00000066926 ENSG00000134308 ENSG00000129514 ENSG00000175567 ENSG00000171791 ENSG00000099942 ENSG00000123124 ENSG00000105664 ENSG00000166263 ENSG00000186847 ENSG00000082175 ENSG00000167880 ENSG00000292234 ENSG00000136997 ENSG00000167972 ENSG00000100219 ENSG00000009307 ENSG00000162889 ENSG00000160194 ENSG00000175793 ENSG00000292149 ENSG00000196839 ENSG00000176153 ENSG00000181026 ENSG00000138378 ENSG00000111537 ENSG00000141480 ENSG00000123892 ENSG00000162972 ENSG00000167996 ENSG00000133661 ENSG00000112378 ENSG00000164690 ENSG00000168646 ENSG00000095002 ENSG00000136872 ENSG00000196689 ENSG00000196208 ENSG00000159399 PMC3248194__F3 RIP Kinase-Mediated Necrosis as an Alternative Mechanism of Photoreceptor Death ENSG00000157625 ENSG00000083799 ENSG00000100504 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC6866135__F1 IRAK1 kinase drives distinct prosurvival responses to microbial infection and ionizing radiation ENSG00000127445 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC6031874__F1 Simplified scheme of transsulfuration pathway ENSG00000205221 PMC3294197__F3 Ingenuity Pathway Analysis of genes that are differentially methylated (P<1.8 × 10−6) between normal mucosa of cancer patients and controls ENSG00000138764 ENSG00000138798 ENSG00000167565 ENSG00000130307 ENSG00000198125 ENSG00000146834 PMC7085392__F3 Activation of Akt after joining to PIP3 by its PH domain PMC11039944__F2 Alpha-fetoprotein in the tumor microenvironment of hepatocellular carcinoma ENSG00000119888 ENSG00000026508 ENSG00000081051 ENSG00000121966 PMC6207598__F2 Toll-like receptors (TLRs) and their role in the evasion of the immune response induced by hMPV ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000164342 PMC7504460__F1 Mechanisms of obesity-induced development of endometrial cancer (EC) ENSG00000129214 ENSG00000159346 ENSG00000140443 PMC8074203__F3 Fructose in Non-Alcoholic Steatohepatitis: Old Relationship and New Insights ENSG00000162711 ENSG00000150782 ENSG00000138030 ENSG00000136869 ENSG00000142224 ENSG00000026103 PMC7504460__F2 Insulin-PI3K signaling facilitates cell proliferation and glucose metabolism via serine/threonine protein kinase B (AKT)-dependent and -independent mechanisms ENSG00000198793 ENSG00000265972 PMC6862746__F9 HCC microenvironment inhibits SIRT4 expression in TAMs and modulates alternative activation of TAMs, which contributes to HCC development ENSG00000118520 ENSG00000089163 ENSG00000168610 PMC7314952__F3 Ferroptosis, NRF2/antioxidant response element (ARE)–GPX4 pathway ENSG00000151012 ENSG00000167468 ENSG00000079999 PMC11037416__F2 Non‐apoptotic regulated cell death mediates reprogramming of the tumour immune microenvironment by macrophages ENSG00000278718 ENSG00000137275 ENSG00000102871 ENSG00000136869 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC11037416__F1 Non‐apoptotic regulated cell death mediates reprogramming of the tumour immune microenvironment by macrophages ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000083290 ENSG00000196839 ENSG00000198793 ENSG00000057663 ENSG00000167468 ENSG00000144848 ENSG00000111684 ENSG00000187855 ENSG00000145782 ENSG00000115419 PMC11028018__F5 Proposed model illustrating the inhibitory effects of GBE on TGFB downstream signaling pathways ENSG00000108821 PMC7252250__F4 Pathway 1: Insufficient activation of immune response in the middle ear epithelium cells in otitis media ENSG00000243414 ENSG00000171855 ENSG00000162711 ENSG00000167207 ENSG00000187796 ENSG00000091592 ENSG00000171791 ENSG00000135341 ENSG00000150782 ENSG00000183735 ENSG00000088888 ENSG00000103490 ENSG00000263528 ENSG00000125538 ENSG00000064012 ENSG00000164342 ENSG00000104365 ENSG00000115008 ENSG00000100906 ENSG00000109320 ENSG00000285433 ENSG00000137757 ENSG00000115267 ENSG00000132357 ENSG00000106100 ENSG00000127666 ENSG00000276561 ENSG00000198183 ENSG00000177606 ENSG00000172936 ENSG00000131323 ENSG00000184216 PMC8377014__F1 Screening of Potential Biomarkers for Gastric Cancer with Diagnostic Value Using Label-free Global Proteome Analysis ENSG00000145321 PMC4437509__F5 Downstream components of ERK in SCN neurons ENSG00000198793 ENSG00000179094 PMC11037416__F5 Pyroptosis mediates macrophage reprogramming of the tumour immune microenvironment ENSG00000278718 ENSG00000162711 ENSG00000145649 ENSG00000189403 ENSG00000136869 ENSG00000168610 ENSG00000147697 ENSG00000073605 PMC4437509__F7 JNK MAPK in the circadian clock ENSG00000132326 ENSG00000179094 PMC4437509__F6 P38 MAPK in the circadian clock ENSG00000132326 ENSG00000179094 PMC11037416__F3 Non‐apoptotic regulated cell death mediates reprogramming of the tumour immune microenvironment by macrophages ENSG00000169245 ENSG00000162711 ENSG00000108691 ENSG00000198053 ENSG00000198793 ENSG00000136869 ENSG00000121807 PMC11993993__F2 LPS proinflammatory signaling pathway ENSG00000108691 ENSG00000170458 ENSG00000125538 ENSG00000172005 ENSG00000172936 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC5346319__F4 p53 dependent and independent tumor suppressive functions of ARF ENSG00000149311 ENSG00000175054 ENSG00000165392 ENSG00000175029 PMC10957552__F1 Unravelling the role of HAS2, GREM1, and PTGS2 gene expression in cumulus cells: implications for human oocyte development competency - a systematic review and integrated bioinformatic analysis ENSG00000170961 ENSG00000164404 ENSG00000130385 ENSG00000073756 PMC11771717__F1 KRAS signaling pathway functions differently in normal cells compared to cancer cells ENSG00000146648 PMC8773878__F5 Extracellular Vesicles as Mediators of Therapy Resistance in the Breast Cancer Microenvironment ENSG00000146648 PMC9636624__F4 Lipidomics combined with transcriptomic and mass spectrometry imaging analysis of the Asiatic toad (Bufo gargarizans) during metamorphosis and bufadienolide accumulation ENSG00000150991 ENSG00000167910 ENSG00000100979 PMC7570648__F2 Each herb in fighting cancer through oxidative stress pathways PMC3957730__F27 Glycolysis and gluconeogenesis in the mesophilic halophile Haloferax volcanii ENSG00000138030 ENSG00000150787 ENSG00000010310 PMC8712267__F5 Proteomic and metabolomic profiling of urine uncovers immune responses in patients with COVID-19 ENSG00000134339 ENSG00000070831 ENSG00000228278 ENSG00000138798 ENSG00000170558 ENSG00000088256 ENSG00000174021 ENSG00000112715 ENSG00000229314 ENSG00000092820 ENSG00000111348 ENSG00000163631 ENSG00000101981 ENSG00000163914 ENSG00000163017 ENSG00000158874 ENSG00000133818 ENSG00000148965 ENSG00000172380 ENSG00000078369 ENSG00000123843 ENSG00000169439 ENSG00000106299 ENSG00000100345 ENSG00000132693 ENSG00000087460 ENSG00000108518 ENSG00000120063 ENSG00000138207 ENSG00000113905 ENSG00000006451 ENSG00000123838 ENSG00000092841 ENSG00000060566 ENSG00000213694 ENSG00000198734 ENSG00000137575 ENSG00000162692 PMC6717289__F6 Our proposed model of KRAS and TP53 oncogenes driving PDAC malignancy via the ARF6–AMAP1 pathway ENSG00000185236 ENSG00000115109 ENSG00000198793 ENSG00000175832 ENSG00000007866 ENSG00000165527 PMC5948914__F2 Gemcitabine pharmacologic pathway ENSG00000284832 ENSG00000060069 ENSG00000118777 ENSG00000129187 ENSG00000127311 ENSG00000114770 ENSG00000124479 ENSG00000048392 ENSG00000167325 ENSG00000171848 ENSG00000158825 ENSG00000014138 ENSG00000124574 ENSG00000112759 ENSG00000177084 ENSG00000198246 ENSG00000197506 PMC5579704__F3 Proposed mechanisms by which dietary polyphenols inhibit EMT and cancer metastasis ENSG00000019991 ENSG00000138798 ENSG00000168036 ENSG00000128602 PMC9273153__F3 Regulation and Signaling of TGFB Autoinduction ENSG00000198793 ENSG00000177606 PMC4103658__F7 GATA6 Levels Modulate Primitive Endoderm Cell Fate Choice and Timing in the Mouse Blastocyst ENSG00000141448 PMC4323494__F9 Schematic model for the involvement of TAK1-NLK in IL-1Beta-triggered ATF5 stabilization and C/EBP activation ENSG00000087095 ENSG00000125538 ENSG00000169136 PMC7438931__F1 mTORC1 pathway and regulation ENSG00000177169 ENSG00000198793 ENSG00000155792 ENSG00000112561 ENSG00000167965 PMC9185982__F6 SRF: a seriously responsible factor in cardiac development and disease ENSG00000172602 ENSG00000119401 ENSG00000168036 ENSG00000141052 ENSG00000122779 ENSG00000136826 PMC2640456__F1A Meta-analysis of microarray-derived data from PACAP-deficient adrenal gland in vivo and PACAP-treated chromaffin cells identifies distinct classes of PACAP-regulated genes ENSG00000108298 ENSG00000100285 ENSG00000198755 ENSG00000110841 ENSG00000189403 ENSG00000171951 ENSG00000111142 ENSG00000215301 ENSG00000161960 PMC6491842__F4 Enriched genes from the ANOVA statistically significant disease status gene list (p-value < 0.05) found in the KEGG Alzheimer's disease pathway (hsa05010) [Kanehisa and Goto, ; Kanehisa et al., , ] ENSG00000132906 ENSG00000159921 ENSG00000142192 ENSG00000002330 ENSG00000144410 ENSG00000197721 ENSG00000120868 ENSG00000168040 ENSG00000119912 ENSG00000164305 PMC4011321__F8 Putative pathway of the inhibition of LPS-activated inflammatory signaling by compound 7 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC7911745__F1 NFKB signaling pathway and the genes associated with BD-like phenotypes ENSG00000104856 ENSG00000137275 ENSG00000109320 ENSG00000102871 ENSG00000172936 ENSG00000175104 ENSG00000127191 PMC4467640__F1 Cellular regulation mediated by extracellular matrix (ECM).Notes: The action of ECM components on the major signaling pathways of tyrosine kinase receptors, their links, and the outcome on tumor cell and chemotherapeutic response ENSG00000162889 ENSG00000002330 ENSG00000198793 ENSG00000136997 PMC7145977__F4 Hypothetical model showing the possible role of Sirtuins and circadian system in the pathogenesis of diabetic lung ENSG00000077463 ENSG00000096717 ENSG00000142082 PMC8165182__F1 An Overview of Lung Cancer in Women and the Impact of Estrogen in Lung Carcinogenesis and Lung Cancer Treatment ENSG00000107562 ENSG00000291971 ENSG00000146648 ENSG00000121966 ENSG00000140443 PMC9175535__F4 Reposition of the fungicide ciclopirox for cancer treatment ENSG00000198793 ENSG00000167965 PMC2684656__F1 Diagrammatic representation of the signalling pathways activated in the unfolded protein response following ER stress ENSG00000144895 ENSG00000127191 PMC8582018__F2 Molecular Mechanisms of Ferroptosis and Its Roles in Hematologic Malignancies ENSG00000108839 ENSG00000151012 ENSG00000167468 PMC8582018__F1 Molecular Mechanisms of Ferroptosis and Its Roles in Hematologic Malignancies ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000197429 ENSG00000111684 ENSG00000115107 ENSG00000127948 ENSG00000057663 ENSG00000136381 ENSG00000079999 PMC3632609__F1 Expression of Tryptophan 2,3-Dioxygenase and Production of Kynurenine Pathway Metabolites in Triple Transgenic Mice and Human Alzheimer's Disease Brain ENSG00000183077 ENSG00000188676 PMC10648005__F1 Main molecular consequences of phosphoinositide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway activation ENSG00000150907 ENSG00000198793 PMC7936154__F1 Examples of potential miRNA-mediated regulation of metabolic pathways in chickens ENSG00000002330 PMC3822721__F3 FHL1 isoform KyoT2 and Notch signaling ENSG00000148400 ENSG00000074181 ENSG00000033800 PMC5919742__F7 Cell-type expression patterns of carbon metabolism-related genes in V ENSG00000159224 ENSG00000198408 ENSG00000197971 ENSG00000134575 ENSG00000154330 ENSG00000124253 PMC4598307__F7 Adenylosuccinate is an insulin secretagogue derived from glucose-induced purine metabolism ENSG00000079387 ENSG00000196839 PMC9530844__F7 Receptor-kinase EGFR-MAPK adaptor proteins mediate the epithelial response to Candida albicans via the cytolytic peptide toxin, candidalysin ENSG00000146648 PMC6890664__F4 Altered cancer pathways in ASL, CCA and HCC ENSG00000070193 ENSG00000185515 ENSG00000138798 ENSG00000168036 ENSG00000087460 ENSG00000141298 ENSG00000149311 ENSG00000163558 ENSG00000163914 ENSG00000150907 ENSG00000155657 ENSG00000196367 ENSG00000130726 PMC7791126__F3 The TGFBeta-induced canonical SMAD and noncanonical signaling pathways ENSG00000087245 ENSG00000198793 ENSG00000171791 ENSG00000049768 ENSG00000076604 ENSG00000111537 ENSG00000163914 ENSG00000107485 ENSG00000100985 ENSG00000175104 ENSG00000204520 ENSG00000125968 ENSG00000104081 ENSG00000026103 PMC6304934__F7 FSIP1 regulates autophagy in breast cancer ENSG00000177169 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000150667 PMC4315163__F4 G protein-coupled receptor pathway is involved in transmembrane signaling and diverse physiological functions including hormone signaling, regulation of cell contraction, cell migration, growth and differentiation ENSG00000010810 PMC7660609__F2 Role of HO-1 in I/R injury and cardioprotection PMC8853744__F2 Senescence in chronic wounds and potential targeted therapies ENSG00000167986 PMC5721403__F1 Targeting to bile acid and lipid metabolism in NASH treatment ENSG00000087245 ENSG00000002330 ENSG00000108821 ENSG00000135929 PMC7460084__F1 Schematic presentation of transforming growth factor-beta (TGFB) signaling pathways ENSG00000198793 PMC8020338__F4 Ingenuity pathway analysis of the TREM1 signaling pathway in the DH82 cell line treated with B ENSG00000184216 PMC8020338__F3 Ingenuity pathway analysis of the Toll-like receptor (TLR) signaling pathway in the DH82 cell line treated with B ENSG00000177606 ENSG00000175104 PMC11351392__F3 Targeting the Nrf2/HO-1 axis for the treatment of IBD ENSG00000162711 ENSG00000167468 PMC1431703__F5 Comparison of results with the known response pathway ENSG00000134371 ENSG00000070831 ENSG00000102007 ENSG00000143436 ENSG00000086504 ENSG00000159111 ENSG00000240682 ENSG00000166902 ENSG00000197601 PMC5824365__F6 String pathway to show the node of PD effects ENSG00000071655 ENSG00000005339 ENSG00000110492 ENSG00000153094 ENSG00000196591 ENSG00000173039 ENSG00000168036 ENSG00000136826 ENSG00000121966 ENSG00000197063 ENSG00000138378 ENSG00000177606 ENSG00000135363 ENSG00000185591 ENSG00000174059 PMC5357489__F3 Cross talk of the Wnt/Beta-catenin pathway with the epidermal growth factor receptor (EGFR) and fibroblast growth factor (FGF) pathways in hepatitis C virus (HCV)-related hepatocellular carcinoma ENSG00000281324 ENSG00000162337 ENSG00000276920 ENSG00000146648 PMC8530779__F7 Triple jeopardy in ageing: COVID-19, co-morbidities and inflamm-ageing ENSG00000088888 ENSG00000125538 ENSG00000172936 ENSG00000131323 ENSG00000276561 ENSG00000164342 PMC9222488__F1 Clinical and Mutation Spectrum of Autosomal Recessive Non-Syndromic Oculocutaneous Albinism (nsOCA) in Pakistan: A Review ENSG00000104044 ENSG00000188467 ENSG00000080166 ENSG00000164175 PMC3840450__F1 The main actors intervening in the canonical and noncanonical NFKB activation pathways ENSG00000104856 ENSG00000173039 PMC10892344__F6 Schematic diagram generated by IPA of the death receptor signaling pathway with which the DEPs with |FC| ≥ 1 ENSG00000160789 ENSG00000100813 ENSG00000168040 ENSG00000175334 PMC3612647__F1 A lithium-sensitive family of small-molecule phosphatases and the sulfate assimilation pathway PMC3840450__F2 Mechanisms of NFKB activation in T-ALL leukemic cells ENSG00000077150 ENSG00000173039 ENSG00000083799 ENSG00000114315 PMC9693004__F3 Hematotoxic Effect of Respiratory Exposure to PHMG-p and Its Integrated Genetic Analysis ENSG00000103642 ENSG00000087245 ENSG00000135218 ENSG00000111537 ENSG00000105397 ENSG00000181610 ENSG00000121940 ENSG00000163914 ENSG00000105697 ENSG00000139687 ENSG00000089820 PMC8838174__F5 In Vitro Anti-Cancer Activities and Mechanisms of Action of 9-Methoxycanthin-6-one from Eurycoma longifolia in Selected Cancer Cell Lines ENSG00000182718 ENSG00000002330 ENSG00000067900 ENSG00000120868 ENSG00000148935 ENSG00000115760 ENSG00000084774 ENSG00000115317 ENSG00000026103 PMC4013580__F6 A schematic model presenting the pathway of BMP4 to affect foam cell formation ENSG00000170365 ENSG00000160179 ENSG00000204217 PMC5454932__F2 Intracellular GH signaling ENSG00000291971 ENSG00000198793 PMC1297590__F2 Ubiquitination of key signaling in anergic T cells ENSG00000069869 ENSG00000078747 ENSG00000173599 ENSG00000177606 PMC6389164__F3 The genes and their functional relationships within the RLR signaling pathway ENSG00000187608 ENSG00000100906 ENSG00000137275 ENSG00000269335 ENSG00000173039 ENSG00000115267 ENSG00000135341 ENSG00000127191 ENSG00000276561 ENSG00000169245 ENSG00000183735 ENSG00000108691 ENSG00000088888 ENSG00000115415 ENSG00000118503 ENSG00000263528 ENSG00000113302 ENSG00000064012 ENSG00000121060 ENSG00000120242 ENSG00000215301 PMC5125391__F2 Role of HDACs in optic nerve damage-induced nuclear atrophy of retinal ganglion cells ENSG00000105327 ENSG00000171720 ENSG00000196591 PMC2603135__F6 Integrated Bioinformatics for Radiation-Induced Pathway Analysis from Proteomics and Microarray Data ENSG00000149311 ENSG00000012048 ENSG00000113456 ENSG00000002330 ENSG00000144554 ENSG00000167325 ENSG00000132646 ENSG00000171848 ENSG00000197299 ENSG00000073111 ENSG00000095002 ENSG00000092330 PMC2603135__F5 Integrated Bioinformatics for Radiation-Induced Pathway Analysis from Proteomics and Microarray Data ENSG00000168209 ENSG00000147649 ENSG00000105497 ENSG00000167749 ENSG00000007237 ENSG00000171848 ENSG00000088247 ENSG00000148308 PMC8276974__F2 Both calcium channel signaling and ITIM containing receptor signaling are involved in leukemia progression by binding to and activating the Ca2+/calmodulin dependent protein kinase family ENSG00000144857 ENSG00000168036 ENSG00000168610 PMC3153165__F1 Roles of the NFKB-mediated inflammatory pathway in cellular transformation and in cancer cell survival, proliferation, invasion, angiogenesis, and metastasis ENSG00000100985 ENSG00000162692 ENSG00000121966 PMC9069786__F11 Interleukin-6 mediated inflammasome activation promotes oral squamous cell carcinoma progression via JAK2/STAT3/Sox4/NLRP3 signaling pathway ENSG00000162711 ENSG00000125538 ENSG00000124766 ENSG00000168610 PMC8591178__F1 Inborn errors of IL-6 family cytokine responses ENSG00000145623 ENSG00000099985 ENSG00000213658 ENSG00000122756 ENSG00000137070 ENSG00000128342 ENSG00000105205 PMC7004353__F9 Cyp1b1 directs Srebp-mediated cholesterol and retinoid synthesis in perinatal liver; Association with retinoic acid activity during fetal development ENSG00000121207 ENSG00000121039 PMC7235771__F1 NGF and TrkA binding, just as BDNF and TrkB, leads to dimerization and autophosphorylation of receptors at tyrosine residues ENSG00000163914 PMC7069804__F2 Schematic of microRNA networks affected by HIV virus ENSG00000064419 ENSG00000070831 PMC5688216__F1 Regulatory T cell development (Churlaud et al ENSG00000049768 ENSG00000135605 PMC5650366__F8 Global gene expression profile of cerebral ischemia-reperfusion injury in rat MCAO model ENSG00000152348 ENSG00000128272 ENSG00000126775 ENSG00000144848 ENSG00000127191 ENSG00000145782 PMC2213224__F8 Interaction of CagA with Crk plays an important role in Helicobacter pylori–induced loss of gastric epithelial cell adhesion ENSG00000291971 ENSG00000099942 PMC4535695__F1 Classical pathway for T cell activation PMC3807853__F9 IL-33 markedly activates murine eosinophils by an NFKB-dependent mechanism differentially dependent upon an IL-4-driven autoinflammatory loop ENSG00000169245 ENSG00000105967 ENSG00000081041 ENSG00000166523 ENSG00000137033 ENSG00000102970 ENSG00000170425 PMC8676434__F4 Evolution of regulated cell death pathways in animals and their evasion by pathogens ENSG00000137275 ENSG00000102871 ENSG00000168040 PMC8761471__F14 Long non‐coding RNA MIR31HG as a prognostic predictor for malignant cancers: A meta‐ and bioinformatics analysis ENSG00000177455 ENSG00000149089 ENSG00000112977 ENSG00000103479 ENSG00000002330 ENSG00000069482 ENSG00000213658 ENSG00000179091 ENSG00000186716 ENSG00000076641 ENSG00000084774 PMC10556577__F1 TGFB signaling pathways (Activin and Bone Morphogenetic Protein) ENSG00000088826 PMC5348720__F1 Viral infections in type 1 diabetes mellitus — why the B cells? ENSG00000184979 ENSG00000103811 ENSG00000105397 ENSG00000115415 ENSG00000107249 ENSG00000125538 ENSG00000137265 ENSG00000112182 ENSG00000276561 PMC3834158__F3 Diets Containing Sea Cucumber (Isostichopus badionotus) Meals Are Hypocholesterolemic in Young Rats ENSG00000130164 ENSG00000073060 ENSG00000042832 ENSG00000170522 ENSG00000113161 ENSG00000169710 ENSG00000160179 PMC6885838__F10 Effects of hydrostatin-SN10 on the JAK2/STAT3 signaling pathway ENSG00000105397 ENSG00000171791 ENSG00000168610 PMC3834158__F4 Diets Containing Sea Cucumber (Isostichopus badionotus) Meals Are Hypocholesterolemic in Young Rats ENSG00000042832 ENSG00000170522 ENSG00000169710 ENSG00000132170 ENSG00000062485 ENSG00000005469 PMC6981958__F1 Interaction of p53 with different E3 ligases ENSG00000291501 PMC10967197__F10 The role of the IGF2BP2-TRPM2-AS/PABPC1-NUMB-NOTCH1 axis in GBC angiogenesis ENSG00000070756 ENSG00000148400 ENSG00000073792 ENSG00000133961 ENSG00000114315 ENSG00000123908 PMC10239798__F7 Swine acute diarrhoea syndrome coronavirus (SADS-CoV) Nsp5 antagonizes type I interferon signaling by cleaving DCP1A ENSG00000115415 ENSG00000272886 PMC7285825__F11 Ingenuity pathway analysis of functional relationships among genes involved in the IFN signaling pathway ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000033800 ENSG00000125347 PMC11820142__SF7_3. Graphical abstract ENSG00000130234 ENSG00000172936 ENSG00000067900 ENSG00000175104 ENSG00000184216 ENSG00000115594 PMC4382988__F4 Ingenuity pathway analysis (IPA) of differentially expressed proteins ENSG00000130300 ENSG00000145681 ENSG00000187608 ENSG00000167768 ENSG00000231925 ENSG00000125999 ENSG00000229314 ENSG00000172183 ENSG00000158125 ENSG00000162510 ENSG00000114993 ENSG00000103490 ENSG00000126803 ENSG00000198183 ENSG00000163131 ENSG00000111331 ENSG00000002549 ENSG00000213672 ENSG00000143196 ENSG00000140464 ENSG00000170477 ENSG00000135919 PMC7584092__F10 Drug-compound-target-pathway network ENSG00000126218 ENSG00000057593 ENSG00000095303 ENSG00000275565 ENSG00000073756 ENSG00000164305 PMC5798330__F2 Transcripts relating to the classical complement pathway are overabundant in subclinical and active TB ENSG00000039537 ENSG00000173369 ENSG00000009724 ENSG00000113600 ENSG00000291559 ENSG00000203710 ENSG00000150337 ENSG00000244731 ENSG00000281123 ENSG00000166278 ENSG00000117322 ENSG00000236625 PMC5955724__F1 Working model for Eph receptor function in tumor promotion and tumor suppression ENSG00000146648 PMC3752772__F2 NFKB activation pathways triggered by TNF family signaling ENSG00000104856 ENSG00000173039 PMC5819904__F1 Core components of the Hippo pathway ENSG00000163914 ENSG00000197905 ENSG00000198670 ENSG00000007866 ENSG00000074219 PMC5819904__F2 Regulation of the Wnt/Beta-catenin signaling pathway ENSG00000162337 ENSG00000134982 PMC8873791__F6 Shenkang Pills on Early-Stage Diabetic Nephropathy in db/db Mice via Inhibiting AURKB/RacGAP1/RhoA Signaling Pathway ENSG00000154736 ENSG00000117650 ENSG00000178999 ENSG00000175591 ENSG00000164362 ENSG00000087586 ENSG00000126895 ENSG00000080709 ENSG00000164171 ENSG00000285348 ENSG00000148848 ENSG00000133216 PMC5819904__F5 Regulation amongst the Wnt/Beta-catenin, LPA and TGFB/Smad signaling pathways and YAP/TAZ of the Hippo pathway ENSG00000134982 ENSG00000138798 ENSG00000163914 ENSG00000198670 ENSG00000131023 PMC6986449__F2 Differentially methylated promoter regions of genes in PI3K-Akt and NFKB signaling pathways during acute malaria ENSG00000002330 ENSG00000105401 ENSG00000198793 ENSG00000168036 ENSG00000198846 PMC11853522__F3 Interaction between nutrient-sensing pathways and mitochondrial oxidative stress and chronic inflammation ENSG00000128606 ENSG00000187531 ENSG00000164430 ENSG00000198793 ENSG00000158828 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000140443 PMC2847476__F3 Immunoregulatory Functions of mTOR Inhibition ENSG00000127528 ENSG00000126353 ENSG00000049768 ENSG00000292210 PMC7378638__F5 Enterohepatic action of FXR and FATP5 ENSG00000042832 ENSG00000160867 PMC4829974__F3 Genomic profiling of Sézary Syndrome identifies alterations of key T-cell signaling and differentiation genes ENSG00000176601 ENSG00000112576 ENSG00000065675 ENSG00000291603 ENSG00000070831 ENSG00000163599 ENSG00000115904 ENSG00000124762 ENSG00000179295 ENSG00000183765 ENSG00000117713 ENSG00000175054 ENSG00000117525 ENSG00000116017 ENSG00000213658 ENSG00000136997 ENSG00000123374 ENSG00000113263 ENSG00000124181 ENSG00000139687 ENSG00000198286 ENSG00000104365 ENSG00000005339 ENSG00000081237 ENSG00000078399 ENSG00000281877 ENSG00000043462 ENSG00000101224 ENSG00000188389 ENSG00000149311 ENSG00000134057 ENSG00000135446 ENSG00000198734 ENSG00000149554 PMC10374588__F2 Pathways controlling pyroptosis, apoptosis, ferroptosis, and cuproptosis ENSG00000278718 ENSG00000162711 ENSG00000136868 ENSG00000138449 ENSG00000137275 ENSG00000102871 ENSG00000163568 ENSG00000123191 ENSG00000072274 ENSG00000091592 ENSG00000168040 ENSG00000127191 ENSG00000121897 ENSG00000182511 ENSG00000084676 ENSG00000111684 ENSG00000042286 ENSG00000136869 ENSG00000137714 PMC7487264__F3 Activation of the PI3-kinase/Akt pathway by VacA ENSG00000124102 ENSG00000134982 ENSG00000168036 PMC4736209__F2 Schematic illustration of an inflammatory IDO activation by LPS and inflammatory cytokines and possible regulatory mechanisms on transcriptional, posttranscriptional, and posttranslational level ENSG00000213658 PMC4736209__F1 Main pathways of TRP degradation including enzymes and their potential stimuli (modified after [, , , ]) PMC6039108__F3 Hematopoietic Stem Cell Gene Therapy –Progress and Lessons Learned ENSG00000143799 ENSG00000012048 ENSG00000083093 ENSG00000051180 ENSG00000177084 ENSG00000139618 PMC10374588__F4 Graphical depiction of the mechanism of classical pyroptosis pathway and non-classical pyroptosis pathway ENSG00000278718 ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC4201220__F2 Wnt/Beta-catenin signaling pathways and a strategy for the phenotype-based drug identification using C ENSG00000134982 ENSG00000204070 ENSG00000168036 PMC9267148__F12 Prediction of CIAPIN1 (Cytokine-Induced Apoptosis Inhibitor 1) Signaling Pathway and Its Role in Cholangiocarcinoma Metastasis ENSG00000005194 PMC9267148__F11 Prediction of CIAPIN1 (Cytokine-Induced Apoptosis Inhibitor 1) Signaling Pathway and Its Role in Cholangiocarcinoma Metastasis ENSG00000136603 ENSG00000157933 ENSG00000105329 ENSG00000157077 PMC4008712__F1 Increases in Insulin Sensitivity among Obese Youth are Associated with Gene Expression Changes in Whole Blood ENSG00000160883 ENSG00000110395 PMC4736209__F3 Possible interaction between inflammatory IDO activation and AhR-mediated effects ENSG00000291971 ENSG00000168610 ENSG00000106546 PMC11536562__F2 Alpha-KG homeostasis and m6A regulation ENSG00000245848 ENSG00000067057 ENSG00000136997 PMC5348361__F9 Components of Huang-Lian-Jie-Du-Decoction act synergistically to exert protective effects in a rat ischemic stroke model ENSG00000178573 PMC7205831__F8 Systems pharmacology reveals the mechanism of activity of Physalis alkekengi L. var. franchetii against lipopolysaccharide‐induced acute lung injury ENSG00000125538 ENSG00000136869 PMC9321602__F1 Impact of DNA damage response defects in cancer cells on response to immunotherapy and radiotherapy ENSG00000143799 ENSG00000012048 ENSG00000083093 ENSG00000105486 ENSG00000138346 ENSG00000197299 ENSG00000051180 ENSG00000310560 PMC3814314__F5 Genome Wide Analysis Reveals Zic3 Interaction with Distal Regulatory Elements of Stage Specific Developmental Genes in Zebrafish ENSG00000087095 ENSG00000157933 ENSG00000146872 ENSG00000133937 ENSG00000291971 ENSG00000134982 ENSG00000183072 ENSG00000156574 ENSG00000168036 ENSG00000164093 ENSG00000198125 ENSG00000104332 PMC11536562__F4 Promotion of ILC3 cell proliferation in m6A-dependent manner ENSG00000091542 PMC11536562__F3 m6A modifications in fetal hematopoiesis and HSC maintenance ENSG00000002330 ENSG00000148400 ENSG00000198492 ENSG00000171791 ENSG00000157240 ENSG00000168283 ENSG00000159216 ENSG00000164736 ENSG00000115415 ENSG00000136997 ENSG00000275272 ENSG00000135828 ENSG00000179348 ENSG00000165819 PMC5389546__F3 let-7c is predicted to target the RAS signaling pathway and miR-98 ENSG00000065833 ENSG00000147862 ENSG00000146909 ENSG00000002330 ENSG00000213658 ENSG00000163914 ENSG00000196712 PMC3814314__F6 Genome Wide Analysis Reveals Zic3 Interaction with Distal Regulatory Elements of Stage Specific Developmental Genes in Zebrafish ENSG00000004975 ENSG00000087510 ENSG00000138795 ENSG00000113140 ENSG00000156574 ENSG00000187140 ENSG00000041982 ENSG00000143801 ENSG00000164161 ENSG00000155011 ENSG00000156925 ENSG00000164093 ENSG00000127616 PMC8740130__F6 Differentially Expressed lncRNAs Related to the Development of Abdominal Fat in Gushi Chickens and Their Interaction Regulatory Network ENSG00000090402 PMC3980586__F1 Molecular Pathways: Emerging Roles of Mammalian Sirtuin SIRT7 in Cancer ENSG00000187531 ENSG00000223367 ENSG00000164587 ENSG00000198793 ENSG00000136997 ENSG00000171863 PMC8382834__F1 Impact of severe hypoglycemia on the heat shock and related protein response ENSG00000103266 ENSG00000121351 ENSG00000120885 ENSG00000184787 ENSG00000089022 PMC9351103__F8 Astragalus mongholicus Bunge and Curcuma aromatica Salisb. inhibits liver metastasis of colon cancer by regulating EMT via the CXCL8/CXCR2 axis and PI3K/AKT/mTOR signaling pathway ENSG00000170558 ENSG00000125538 ENSG00000198793 ENSG00000169429 PMC4033570__F5 Simplified network diagram showing the involvement of JNK and p38 in the system ENSG00000099985 ENSG00000175104 ENSG00000168610 PMC12205809__F6 Pro-inflammatory C-X-C motif chemokines (CXCs) play a crucial role in the progression and development of breast cancer in aged patients, postmenopausal women, animal models, and senescent cells ENSG00000169248 ENSG00000169245 ENSG00000186810 ENSG00000107562 ENSG00000164946 ENSG00000163739 ENSG00000138755 ENSG00000124766 ENSG00000169429 ENSG00000121966 PMC12205809__F5 Stroma phenotype of catabolic tumor ENSG00000164690 ENSG00000168610 PMC6089851__F2 Major downstream targets of ERK1/2 in the MAPK pathway ENSG00000291971 ENSG00000010810 ENSG00000177606 ENSG00000136997 PMC4926232__F7 FGFR2IIIb-MAPK Activity Is Required for Epithelial Cell Fate Decision in the Lower Müllerian Duct ENSG00000159216 ENSG00000140285 ENSG00000163217 PMC6089851__F1 Major RAS family numbers ENSG00000123728 ENSG00000108551 ENSG00000165527 ENSG00000168256 ENSG00000008853 ENSG00000197885 ENSG00000125249 ENSG00000138175 ENSG00000163914 ENSG00000168374 ENSG00000113966 ENSG00000128045 ENSG00000214087 ENSG00000162595 ENSG00000134287 ENSG00000284984 ENSG00000100302 ENSG00000139725 ENSG00000172602 ENSG00000152214 ENSG00000088320 ENSG00000164292 ENSG00000164949 ENSG00000179674 ENSG00000175906 ENSG00000141748 ENSG00000070831 ENSG00000185305 ENSG00000134533 ENSG00000196503 ENSG00000113595 ENSG00000103710 ENSG00000176490 ENSG00000152213 ENSG00000122035 ENSG00000167550 ENSG00000100276 ENSG00000104140 ENSG00000108830 ENSG00000169750 ENSG00000143761 ENSG00000165023 ENSG00000270885 ENSG00000072422 ENSG00000126458 ENSG00000133818 ENSG00000187682 ENSG00000213465 ENSG00000169379 ENSG00000181467 ENSG00000139890 ENSG00000120805 ENSG00000132341 PMC9452894__F3 Chemistry and efficacy benefits of polysaccharides from Atractylodes macrocephala Koidz ENSG00000168036 PMC2455793__F1 Interaction between two known Egr1 target genes, PTEN and fibronectin achieves a delicate balance between attachment and apoptosis of detached cells (anoikis) ENSG00000002330 ENSG00000168036 ENSG00000026103 PMC6089851__F3 Activation and feedback regulation of the MAPK pathway ENSG00000138166 ENSG00000163235 ENSG00000291971 ENSG00000113070 ENSG00000010810 ENSG00000171791 PMC9138619__F3A Molecular Signature of Neuroinflammation Induced in Cytokine-Stimulated Human Cortical Spheroids ENSG00000104856 ENSG00000278718 ENSG00000169248 ENSG00000213928 ENSG00000107562 ENSG00000165197 ENSG00000187266 ENSG00000121807 ENSG00000122194 ENSG00000121966 ENSG00000010671 ENSG00000095585 ENSG00000150782 ENSG00000077150 ENSG00000135960 ENSG00000149968 ENSG00000163734 ENSG00000037280 ENSG00000006327 ENSG00000081041 ENSG00000099985 ENSG00000108342 ENSG00000188729 ENSG00000007908 ENSG00000006062 ENSG00000073756 ENSG00000276561 ENSG00000169245 ENSG00000186810 ENSG00000226275 ENSG00000170962 ENSG00000177606 ENSG00000184371 ENSG00000126353 ENSG00000115009 ENSG00000150630 PMC8888757__F8 Proposed simplified model of ADAP1-mediated T cell signaling stimulation leading to latent HIV-1 reactivation ENSG00000177606 ENSG00000163631 PMC9027133__F5 Research Status of the Orphan G Protein Coupled Receptor 158 and Future Perspectives ENSG00000182901 ENSG00000076716 ENSG00000151025 PMC9118275__F3 MicroRNA-96: A therapeutic and diagnostic tumor marker ENSG00000134982 ENSG00000106236 ENSG00000168036 ENSG00000106483 PMC11898300__F5 Diagram of tumor cell biomechanical perception, conduction, and effect mechanism ENSG00000198793 ENSG00000163914 ENSG00000103335 PMC8243062__F3 NRF2 signalling pathway and antioxidant therapeutic approaches ENSG00000012048 ENSG00000183735 ENSG00000178573 ENSG00000156273 ENSG00000079999 PMC8806153__F3 Metabolism of memory CD8+ T cell differentiation ENSG00000103569 ENSG00000026103 PMC9340488__F4 Inflammatory pathways in COVID‐19: Mechanism and therapeutic interventions ENSG00000104856 ENSG00000213928 ENSG00000102871 ENSG00000168610 ENSG00000276561 ENSG00000169245 ENSG00000108691 ENSG00000105397 ENSG00000115415 ENSG00000130234 ENSG00000138755 ENSG00000125538 ENSG00000184012 ENSG00000136869 ENSG00000172936 ENSG00000164342 PMC9340488__F2 Inflammatory pathways in COVID‐19: Mechanism and therapeutic interventions ENSG00000174125 ENSG00000239732 ENSG00000130234 ENSG00000184012 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC3328890__F1 ROS-dependent and -independent apoptosis induced by particulate pollutants ENSG00000002330 ENSG00000198125 ENSG00000106546 PMC5891223__F5 Epidermal Growth Factor Receptor Signaling to the MAPK Pathway Bypasses RAS in Pancreatic Cancer Cells ENSG00000070831 ENSG00000149269 ENSG00000138798 ENSG00000146648 PMC8517597__F2 Interaction between intestinal microbiota and tumour immunity in the tumour microenvironment ENSG00000169245 ENSG00000154059 ENSG00000143387 PMC2949087__F5 Mitochondria and neuroplasticity ENSG00000142192 ENSG00000158828 ENSG00000197386 PMC6876280__F1 An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer ENSG00000074266 ENSG00000178691 PMC1890373__F2 Molecular system bioenergetics: regulation of substrate supply in response to heart energy demands ENSG00000175054 ENSG00000135218 PMC7912608__F5 Diversity of NO functioning in cancer ENSG00000105894 ENSG00000168036 ENSG00000121966 PMC8429462__F8 Oxidized mitochondrial DNA sensing by STING signaling promotes the antitumor effect of an irradiated immunogenic cancer cell vaccine ENSG00000183735 PMC5448443__F1 Amyloidogenic and non-amyloidogenic processing of the APP ENSG00000142192 ENSG00000138798 PMC4450051__F4 Regulation of Toll-like Receptor Signaling by the SF3a mRNA Splicing Complex ENSG00000101146 ENSG00000105656 ENSG00000168040 ENSG00000150455 ENSG00000276561 ENSG00000143387 ENSG00000239732 ENSG00000144410 ENSG00000170458 ENSG00000125538 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC8113849__F1 Estrogen and estrogen receptor-mediated pathways in thyroid cancer ENSG00000124102 ENSG00000140575 ENSG00000198793 ENSG00000086991 ENSG00000168036 ENSG00000146648 ENSG00000125084 ENSG00000221926 PMC8621031__F2 Resveratrol against Cardiac Fibrosis: Research Progress in Experimental Animal Models ENSG00000096717 PMC4904902__F1 AMBRA1, a novel mitophagy receptor ENSG00000110497 ENSG00000158828 ENSG00000171791 PMC4560339__F1 Multimodality targeting of MM in the context of the BM microenvironment ENSG00000019991 ENSG00000141867 ENSG00000107562 ENSG00000136997 ENSG00000026751 ENSG00000112715 PMC5149521__F3 PKB associated signal transduction pathways ENSG00000002330 ENSG00000198793 ENSG00000084774 PMC9578220__F6 Novel chromatin regulator-related immune checkpoint related gene prognostic signature and potential candidate drugs for endometrial cancer patients ENSG00000102245 ENSG00000276051 ENSG00000186827 PMC6103702__F5 Representative cell cycle pathway between PCOS arrested and non-arrested 2-cell embryos ENSG00000145604 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000164754 ENSG00000277273 ENSG00000093009 PMC7662147__F2 Life cycle and cleavage of SARS-CoV-2 and ENaC in airway cells ENSG00000140564 ENSG00000130234 ENSG00000184012 PMC5751286__F2 Schematic view of (A) the NFKB signaling pathway and (B) the JAK-STAT signaling pathway that contribute to the pathogenesis of psoriasis and its novel targeting molecules ENSG00000088888 ENSG00000162892 ENSG00000142224 PMC4230721__F3 Compounds used as anti-fibrotic therapies in other organs and their mode of action ENSG00000019991 ENSG00000198793 PMC7576264__F9 Rab27A promotes ROS production and apoptosis via suppressing miR‐124‐3p and increasing STAT3/RelA pathway in inflammatory colonic cells ENSG00000173039 ENSG00000168610 PMC2605487__F2 Signalling pathways involved in the induction of astrocyte specification/differentiation ENSG00000170365 ENSG00000242689 ENSG00000131095 ENSG00000128342 ENSG00000168610 PMC4578651__F4 Chymomyza costata exposed to Long Day (LD), Short Day (SD) and Transfer (T) from LD to SD photoperiodic conditions ENSG00000282899 ENSG00000162961 ENSG00000123908 ENSG00000276876 PMC7962892__F1 TNFAlpha-induced signaling pathway of cell survival, apoptosis and necroptosis ENSG00000102871 ENSG00000082512 ENSG00000168040 ENSG00000168404 ENSG00000127191 PMC8530315__F7 VitD3 effects in D3-MDMs during DENV-2 infection ENSG00000111012 ENSG00000213928 ENSG00000239732 ENSG00000089127 ENSG00000115415 ENSG00000164342 PMC6488436__F1 Sphingolipid metabolism ENSG00000139624 ENSG00000100422 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000102172 ENSG00000143418 PMC5816341__F1 Schematic diagram of the three pathways of the complement system, highlighting the upregulator (properdin) and downregulator (factor H) of the alternative pathway ENSG00000039537 ENSG00000244731 ENSG00000158526 ENSG00000166278 ENSG00000167721 ENSG00000007520 ENSG00000182326 ENSG00000062485 PMC8050350__F5 Metabolic Signature of Autoreactive T cells in Rheumatoid Arthritis ENSG00000148942 ENSG00000172340 PMC7156472__F6 Identification of a novel tumor angiogenesis inhibitor targeting Shh/Gli1 signaling pathway in Non-small cell lung cancer ENSG00000164690 ENSG00000167508 PMC3377280__F7 Aurora-A expressing tumour cells are deficient for homology-directed DNA double strand-break repair and sensitive to PARP inhibition ENSG00000051180 ENSG00000166851 PMC9614365__F1 Metabolic requirements of Th17 cells and of B cells: Regulation and defects in health and in inflammatory diseases ENSG00000138795 ENSG00000111537 ENSG00000049768 ENSG00000115419 PMC7411130__F3 Regulators of the complement pathway ENSG00000039537 ENSG00000203710 ENSG00000166278 ENSG00000236625 PMC6938958__F8 Identification of Regulatory Modules That Stratify Lupus Disease Mechanism through Integrating Multi-Omics Data ENSG00000213928 ENSG00000120690 ENSG00000187608 ENSG00000205250 ENSG00000230034 ENSG00000070444 ENSG00000152778 ENSG00000105397 ENSG00000115415 ENSG00000182185 ENSG00000136997 ENSG00000197299 ENSG00000133740 ENSG00000051180 ENSG00000041357 PMC2136409__F7 Genetic and epigenetic mechanisms of gene regulation during lens development ENSG00000178573 PMC3253704__F1 Prominent signaling pathways involved with PDAC tumoral compartment and stromal compartment crosstalk ENSG00000164690 ENSG00000128602 PMC7913053__F1 Senotherapeutics: Targeting senescence in idiopathic pulmonary fibrosis ENSG00000166340 ENSG00000130826 ENSG00000086991 ENSG00000164362 ENSG00000128513 PMC3232381__F1 Tumour necrosis factor receptor 1 (TNFR1) and its signalling pathways ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC4742793__F9 Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin ENSG00000154764 ENSG00000281324 ENSG00000162337 PMC5624958__F7 Schematic diagram of the proposed mechanism by which OCA may modulate the IL-6/Jak-2/STAT3 signalling pathway in HCC cells ENSG00000125538 ENSG00000168610 PMC6939459__F10 Conceptual models of mitochondrial metabolite transport and the consequence of metabolic perturbations on Th1 cell activation ENSG00000122966 ENSG00000172005 ENSG00000026103 PMC8383068__F1 Proteomics Mapping of the ISGylation Landscape in Innate Immunity ENSG00000184979 ENSG00000159128 ENSG00000213928 ENSG00000187608 ENSG00000291971 ENSG00000156587 ENSG00000027697 ENSG00000142166 ENSG00000182179 PMC6933925__F2 Possible rational combination treatments for HH/GLI-associated cancers simultaneously targeting HH/GLI and HH-regulated immunosuppressive and tumor-promoting signals ENSG00000111537 ENSG00000125538 ENSG00000274736 ENSG00000164690 ENSG00000121807 ENSG00000168610 PMC3562341__F4 Accumulation of Splice Variants and Transcripts in Response to PI3K Inhibition in T Cells ENSG00000291603 ENSG00000107338 ENSG00000213658 ENSG00000010810 ENSG00000113263 ENSG00000135605 PMC5908737__F3 MUC1-C ACTIVATES POLYCOMB REPRESSIVE COMPLEXES AND DOWNREGULATES TUMOR SUPPRESSOR GENES IN HUMAN CANCER CELLS ENSG00000168283 ENSG00000042832 ENSG00000136997 PMC6940409__F2 Photic- and non-photic-responsive MAPK signaling pathways in the brain PMC5416959__F10 RFC-PCNA complex inhibiting cell proliferation ENSG00000132646 ENSG00000163918 ENSG00000035928 ENSG00000133119 PMC9539821__F2 Epigenetic factors in breast cancer therapy ENSG00000134982 ENSG00000050165 ENSG00000168036 PMC3142564__F1 Targeting the phosphoinositide 3-kinase (PI3K) pathway in cancer ENSG00000002330 ENSG00000198793 ENSG00000198670 PMC6625911__F1 CaMKK2 and advanced glycation endproducts (AGEs) within the bone microenvironment ENSG00000245848 ENSG00000125398 ENSG00000172216 ENSG00000162551 ENSG00000110931 ENSG00000136869 ENSG00000102575 ENSG00000131196 ENSG00000143387 PMC2657945__F1 The TSC-mTOR signaling ENSG00000118515 PMC7983599__F1 Effect of Thyroid Hormones on Adipose Tissue Flexibility ENSG00000170893 PMC2657945__F2 Regulation of the mTORC1 pathway by two distinct small GTPases PMC6497036__F10 Proposed mode of action for RHOA to maintain TE characteristics in the expanding blastocyst ENSG00000126016 ENSG00000186575 PMC9138619__F2A Molecular Signature of Neuroinflammation Induced in Cytokine-Stimulated Human Cortical Spheroids ENSG00000169248 ENSG00000167207 ENSG00000125735 ENSG00000183625 ENSG00000111321 ENSG00000187266 ENSG00000121807 ENSG00000122194 ENSG00000010671 ENSG00000095585 ENSG00000164400 ENSG00000037280 ENSG00000128342 ENSG00000026103 ENSG00000081041 ENSG00000099985 ENSG00000188729 ENSG00000173039 ENSG00000007908 ENSG00000162924 ENSG00000125347 ENSG00000127191 ENSG00000169245 ENSG00000186810 ENSG00000226275 ENSG00000108691 ENSG00000115009 ENSG00000150630 PMC8273970__F10 EIF4A3-induced circ_0084615 contributes to the progression of colorectal cancer via miR-599/ONECUT2 pathway ENSG00000119547 ENSG00000169554 ENSG00000112715 ENSG00000123908 ENSG00000198363 PMC5859524__F1 Regulation of the cell cycle ENSG00000149311 ENSG00000175054 PMC2424193__F6 Chemical Rescue of ΔF508-CFTR Mimics Genetic Repair in Cystic Fibrosis Bronchial Epithelial Cells ENSG00000111537 ENSG00000109320 ENSG00000263528 ENSG00000269335 ENSG00000170606 ENSG00000113520 ENSG00000001626 ENSG00000175104 ENSG00000127191 ENSG00000168610 PMC3539910__F2 Carcinogenesis of colorectal cancer cells and role of different miRNAs in cancer pathways ENSG00000132906 ENSG00000002330 ENSG00000134982 ENSG00000168036 ENSG00000146648 ENSG00000164305 PMC8678087__F1 Histone Lysine Methylation and Long Non-Coding RNA: The New Target Players in Skeletal Muscle Cell Regeneration ENSG00000009709 ENSG00000111049 ENSG00000122180 ENSG00000135903 PMC4270317__F5 Cell cycle pathway ENSG00000144063 ENSG00000123374 ENSG00000277273 ENSG00000198734 ENSG00000078098 PMC11994677__F1 Crosstalk between KTRM and renal cellular networks ENSG00000143546 ENSG00000163220 ENSG00000164400 ENSG00000172936 ENSG00000168610 PMC5345622__F1 Occurrence and regulatory mechanisms of ferroptosis in a cell ENSG00000167107 ENSG00000167468 ENSG00000197429 ENSG00000136381 ENSG00000062485 PMC7512067__F6 Summary diagram outlines the working mechanisms of oridonin in FaDu cells ENSG00000170558 ENSG00000168036 ENSG00000277641 PMC4780413__F6 Reduced PARP1 as a Serum Biomarker for Graft Rejection in Kidney Transplantation ENSG00000143799 ENSG00000140992 ENSG00000019991 ENSG00000105329 ENSG00000171723 ENSG00000100883 ENSG00000197746 ENSG00000087085 ENSG00000168036 ENSG00000162772 ENSG00000171791 ENSG00000076864 ENSG00000116918 ENSG00000112290 ENSG00000129757 ENSG00000143801 ENSG00000213658 ENSG00000125538 ENSG00000113520 ENSG00000162521 ENSG00000164506 ENSG00000102935 ENSG00000026103 ENSG00000104365 ENSG00000259207 ENSG00000168040 ENSG00000073756 ENSG00000007171 ENSG00000149311 ENSG00000111537 ENSG00000160224 ENSG00000160180 ENSG00000139351 ENSG00000136940 PMC9027478__F1 Notch signaling network in muscle stem cells during development, homeostasis, and disease ENSG00000009709 ENSG00000168214 ENSG00000128917 PMC2637474__F7 Hypothetical pathway involved in general cerebellum-mediated motor learning ENSG00000145321 ENSG00000062485 PMC4412130__F1 Eukaryotic mechanisms that manage replication– transcription conflicts ENSG00000175054 ENSG00000260314 ENSG00000140451 ENSG00000183479 PMC12205809__F4 Interleukin (IL)-10/11/tumor necrosis factor (TNF) and transforming growth factor (TGF) pro-inflammatory cytokines play a role in breast cancer in postmenopausal women and senescence cells, as shown in the illustration ENSG00000115884 ENSG00000137070 ENSG00000185591 ENSG00000168610 PMC12205809__F3 Pro-inflammatory cytokines (interleukins/ILs) play a role in aged/postmenopausal breast cancer women or animal model/senescence cells, as depicted in the illustration ENSG00000164430 ENSG00000115415 ENSG00000173120 ENSG00000168610 PMC7967218__F2 Histone acetylation regulates genes involved in cancer progression ENSG00000168283 ENSG00000119888 ENSG00000132698 ENSG00000103241 ENSG00000104413 ENSG00000128602 ENSG00000149418 PMC4323104__F7 Clinical Proteomics Identifies Urinary CD14 as a Potential Biomarker for Diagnosis of Stable Coronary Artery Disease ENSG00000180210 ENSG00000122694 ENSG00000170458 ENSG00000274334 ENSG00000170266 ENSG00000170293 ENSG00000065243 ENSG00000116977 ENSG00000179163 PMC12065104__F5 Molecular and signaling changes between a normal melanocyte and a melanocytic melanocyte ENSG00000111537 ENSG00000115415 ENSG00000135446 ENSG00000105810 ENSG00000125347 ENSG00000196712 PMC5350610__F3 The consequences of perturbation of CUL4CRBN E3 ligase function ENSG00000167986 ENSG00000113851 PMC3618441__F1 Membrane-initiated Actions of Estradiol that Regulate Reproduction, Energy Balance and Body Temperature ENSG00000124181 ENSG00000168610 PMC7160552__F3 Recent advances in unraveling the molecular mechanisms and functions of HOXA11-AS in human cancers and other diseases ENSG00000156103 ENSG00000052344 ENSG00000156574 ENSG00000145321 ENSG00000168036 ENSG00000127528 ENSG00000105996 PMC7160552__F2 Schematic diagram that introduces in detail the molecular mechanisms, clinical values and cell phenotypes affected by HOXA11-AS in different tumor types, including (A) NSCLC, (B) HCC, (C) glioma, (D) CC, and (E) BC ENSG00000138166 ENSG00000135446 ENSG00000291387 ENSG00000123374 ENSG00000168610 ENSG00000105996 ENSG00000131023 ENSG00000113448 PMC8509647__F3 Pathogenesis of IgA Nephropathy: Current Understanding and Implications for Development of Disease-Specific Treatment ENSG00000039537 ENSG00000113600 ENSG00000116785 ENSG00000244414 ENSG00000134365 ENSG00000203710 ENSG00000292002 ENSG00000244731 ENSG00000166278 ENSG00000292003 ENSG00000236625 PMC7853511__F8 Cross-effect of TRPV1 and EP3 receptor on coughs and bronchopulmonary C-neural activities ENSG00000134982 ENSG00000196689 PMC5299705__F7 The regulatory network of HOTAIRM1 involved in the autophagy pathway and the degradation of PML-RARA ENSG00000177169 ENSG00000156171 PMC9576592__F7 Schematic model depicting the functions of SNHG5 during the proliferation and cancer stem cell-like properties of HCC ENSG00000154342 ENSG00000026508 ENSG00000168036 ENSG00000196628 ENSG00000125084 PMC2257939__F2 Bimodal genes highlighted in KEGG ECM-receptor interaction diagram ENSG00000136457 ENSG00000135218 ENSG00000110799 ENSG00000026508 PMC7843937__F8 An overview of pathways involved in mediating Cor and DDP-induced cellular effects ENSG00000198793 ENSG00000164305 PMC7768751__F1 Role of Diet and Phospholipase D enzyme in the complex network of choline pathways and Choline-Mediated 1C metabolism ENSG00000173599 ENSG00000133027 PMC7456829__F4 Pathways of anti-TNF monoclonal antibodies action in Crohn's disease (CD) ENSG00000203747 ENSG00000028137 ENSG00000026103 PMC7037830__F3 Binding mechanism of LPS for TLR4 activation ENSG00000170458 ENSG00000136869 PMC4536973__F1 Physiopathological actions of periostin activation ENSG00000124102 ENSG00000277641 ENSG00000146648 PMC9312508__F10 Host-Genome Similarity Characterizes the Adaption of SARS-CoV-2 to Humans ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC9329783__F1 Sweet Taste Signaling: The Core Pathways and Regulatory Mechanisms ENSG00000185933 ENSG00000070985 ENSG00000137841 PMC4423042__F6 Cartoon representing LPA-activated signaling cascades that regulate OHC motility, as suggested by our results and previous studies (in black font), as well as potential mediators and interactions that require confirmation (gray font) ENSG00000106683 ENSG00000198670 PMC7691485__F3 Basic components and rough characteristics of each indicated signaling pathway in relation to primary cilia ENSG00000134853 ENSG00000128602 ENSG00000146648 PMC5789373__F2 Cross-talk of mTOR with other signaling pathways ENSG00000157933 PMC7770202__F1 Signaling pathways of interest in the peripheral and central nociceptive pathway ENSG00000132329 ENSG00000104321 ENSG00000109320 ENSG00000125538 ENSG00000173039 ENSG00000115353 ENSG00000110680 ENSG00000162772 ENSG00000196689 PMC9329783__F3 Sweet Taste Signaling: The Core Pathways and Regulatory Mechanisms ENSG00000185933 ENSG00000070985 ENSG00000168610 ENSG00000137841 PMC7770202__F8 Response to aging in the mouse somatosensory nervous system ENSG00000132329 ENSG00000104321 ENSG00000109320 ENSG00000173039 ENSG00000110680 ENSG00000162772 PMC6613841__F8 Proposed mechanisms underlying the regulation of innate immune response by influenza virus H5N1/HM M2 protein ENSG00000088888 ENSG00000276561 ENSG00000057663 PMC2984239__F5 Merged network pathway analysis of proteins involved in cellular assembly and organization, cellular compromise, and protein folding that were identified in cytoplasmic fraction ENSG00000215021 ENSG00000173113 ENSG00000099246 ENSG00000104907 PMC6192633__F8 GPR108 works as a dual functional regulator to balance the TLR-triggered immune response ENSG00000125734 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC4350884__F8 EtOH and INK128 impact on the mTOR pathway and cellular response ENSG00000198793 ENSG00000164327 PMC11215396__F1 CXCL8 and its cognate receptors CXCR1/CXCR2 in primary myelofibrosis ENSG00000117400 ENSG00000187266 PMC6722206__F1 miRNAs orchestrate T cell metabolic reprogramming ENSG00000198793 PMC6166692__F2 Redox-Sensitive Innate Immune Pathways During Macrophage Activation in Type 1 Diabetes ENSG00000111537 ENSG00000115415 ENSG00000172936 ENSG00000177688 PMC6365085__F9 MicroRNA-223 attenuates LPS-induced inflammation in acute lung injury model via the NLRP3 inflammasome ENSG00000162711 ENSG00000143878 ENSG00000125538 ENSG00000136869 PMC9589179__F7 Mining of transcriptome identifies CD109 and LRP12 as possible biomarkers and deregulation mechanism of T cell receptor pathway in Acute Myeloid Leukemia ENSG00000089692 ENSG00000153283 ENSG00000181847 ENSG00000134982 ENSG00000104760 ENSG00000150637 PMC2921074__F1 Modulating immune function and controlling inflammation ENSG00000189403 ENSG00000168610 PMC8257046__F8 SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects ENSG00000004975 ENSG00000067900 PMC4227186__F6 TCDD induced HIF-1A molecular signaling ENSG00000175567 ENSG00000112715 ENSG00000106546 PMC5421298__F6 Gene expression changes in the TGFB signaling pathway ENSG00000107779 ENSG00000005339 ENSG00000157077 ENSG00000183691 ENSG00000134363 ENSG00000108443 ENSG00000205250 ENSG00000137801 ENSG00000170365 ENSG00000095739 ENSG00000198176 ENSG00000175189 ENSG00000198742 ENSG00000113558 ENSG00000136997 ENSG00000185591 ENSG00000135503 ENSG00000080839 ENSG00000204217 PMC5421298__F5 Gene expression changes in the Wnt/Beta-catenin signaling pathway ENSG00000004975 ENSG00000166167 ENSG00000005339 ENSG00000149782 ENSG00000118971 ENSG00000164736 ENSG00000148660 ENSG00000095739 ENSG00000177606 ENSG00000136997 ENSG00000102312 ENSG00000185269 ENSG00000175792 PMC7037830__F4 Illustration of TLR4 signaling pathway ENSG00000183735 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC4859668__F3 DDX3 is involved in Wnt/Beta-catenin pathway ENSG00000281324 ENSG00000137673 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC10472599__F8 Single-cell transcriptomics reveals multiple chemoresistant properties in leukemic stem and progenitor cells in pediatric AML ENSG00000178860 ENSG00000107562 ENSG00000198793 ENSG00000105810 ENSG00000174059 ENSG00000121966 PMC2681728__F8 Proposed model of the role of p47 in E ENSG00000010810 ENSG00000180628 PMC8469604__F6 Uncovering the Metabolic and Stress Responses of Human Embryonic Stem Cells to FTH1 Gene Silencing ENSG00000181019 ENSG00000175567 ENSG00000079999 PMC2933544__F3 Proposed model of epidermal growth factor receptor (EGFR) aberrant activation and trafficking in the setting of cigarette smoke (CS) ENSG00000138798 ENSG00000146648 ENSG00000062485 PMC4464707__F4 Integrated regulatory graph was constructed as a prediction for the regulatory pathway of IMP metabolism ENSG00000165556 ENSG00000152661 ENSG00000126803 ENSG00000170606 ENSG00000092067 ENSG00000101425 ENSG00000006007 ENSG00000137801 PMC4078307__F1 Disruption of aminergic signalling reveals novel compounds with distinct inhibitory effects on mosquito reproduction, locomotor function and survival ENSG00000123454 ENSG00000141744 PMC7304430__F12 Development of a novel in vitro insulin resistance model in primary human tenocytes for diabetic tendinopathy research ENSG00000102871 ENSG00000169047 ENSG00000127191 PMC3726197__F1 Signaling axis exploited in the phosphatase and tensin homologue deleted on chromosome 10 (PTEN) mutant mouse model of prostate tumorigenesis ENSG00000002330 ENSG00000198793 PMC5869686__F5 Representation of the TCA cycle and glyoxylate shunt pathway ENSG00000143252 ENSG00000073578 ENSG00000117118 PMC6500618__F7 A Network Pharmacology Study on the Active Ingredients and Potential Targets of Tripterygium wilfordii Hook for Treatment of Rheumatoid Arthritis ENSG00000110944 ENSG00000177606 ENSG00000173039 ENSG00000164305 PMC9653866__F2 BTN3A: A Promising Immune Checkpoint for Cancer Prognosis and Treatment ENSG00000111537 ENSG00000111801 ENSG00000134982 ENSG00000113520 ENSG00000168610 PMC4160455__F1 Multiple mechanisms lead to the development of PPCM in mice ENSG00000168610 ENSG00000178568 PMC11121000__F1 Insights into Salinity Tolerance in Wheat ENSG00000105205 PMC5349926__F2 Discovery and replication of microRNAs for breast cancer risk using genome-wide profiling ENSG00000105327 ENSG00000181274 ENSG00000162595 ENSG00000153094 ENSG00000088305 ENSG00000176058 ENSG00000171791 ENSG00000166851 ENSG00000132693 ENSG00000136826 ENSG00000198901 ENSG00000183735 ENSG00000170775 ENSG00000110148 ENSG00000188130 ENSG00000185591 ENSG00000105810 ENSG00000104081 ENSG00000158050 PMC9041553__F2 Ex Vivo Test for Measuring Complement Attack on Endothelial Cells: From Research to Bedside ENSG00000039537 ENSG00000113600 ENSG00000203710 ENSG00000122194 ENSG00000062485 ENSG00000084774 PMC8393646__F9 Metformin Is a Pyridoxal-5′-phosphate (PLP)-Competitive Inhibitor of SHMT2 PMC3110099__F14 Schematic diagram to show that knockdown of Akt1 leads to upregulation of Akt2 in response to oxidative stress and its regulation of oxidative-stress-induced apoptosis through three pathways PMC4324359__F2 Differentially expressed gene enrichment of the top scored pathway maps ENSG00000128272 ENSG00000177606 ENSG00000100219 ENSG00000127191 PMC5601305__F1 Mechanisms used by Toxoplasma gondii, type I strain, to modulate mainly immune system at its favor ENSG00000111537 ENSG00000105329 ENSG00000138798 ENSG00000007171 ENSG00000026103 PMC7890269__F7 Proposed model ENSG00000112561 PMC7457135__F1 Protective and detrimental roles of mitochondrial reactive oxygen species (mtROS) during infection ENSG00000174125 ENSG00000162711 ENSG00000088888 ENSG00000198793 ENSG00000136869 ENSG00000130159 ENSG00000142082 ENSG00000175104 ENSG00000079999 PMC8455891__F1 Neurodevelopmental Disorders (NDD) Caused by Genomic Alterations of the Ubiquitin-Proteasome System (UPS): the Possible Contribution of Immune Dysregulation to Disease Pathogenesis ENSG00000108395 ENSG00000044090 ENSG00000113851 ENSG00000143756 ENSG00000153827 ENSG00000124356 ENSG00000278787 ENSG00000008853 ENSG00000169918 ENSG00000187566 ENSG00000103657 ENSG00000101871 ENSG00000078747 ENSG00000143222 ENSG00000174943 ENSG00000273820 ENSG00000124422 ENSG00000103266 ENSG00000119669 ENSG00000288188 ENSG00000138411 ENSG00000109654 ENSG00000072803 ENSG00000086758 ENSG00000101695 ENSG00000184979 ENSG00000120925 ENSG00000163961 ENSG00000158290 ENSG00000085382 ENSG00000066427 ENSG00000103264 ENSG00000148356 ENSG00000138081 PMC10531449__F3 Transcriptomics of Canine Inflammatory Mammary Cancer Treated with Empty Cowpea Mosaic Virus Implicates Neutrophils in Anti-Tumor Immunity ENSG00000148346 ENSG00000121058 ENSG00000198517 ENSG00000105656 ENSG00000157625 ENSG00000168040 PMC3243339__F8 Depiction of how D1 and c-Myc proteins regulate CDDP-induced cell death, with arrow indicating induction and hyphen (-|) indicating inhibition ENSG00000104856 ENSG00000109320 ENSG00000089685 ENSG00000173039 PMC3567827__F1 Hh signal transduction in Drosophila and mammalian systems ENSG00000180447 ENSG00000166813 ENSG00000183098 ENSG00000121067 ENSG00000076716 ENSG00000128602 PMC11943624__F3 Key metabolic pathway components and targets for nanomedicine-based targeting (rectangles represent components, rounded rectangles represent enzymes, and dashed lines and multiple arrows indicate omitted multistep reactions) ENSG00000228716 ENSG00000106348 ENSG00000178035 ENSG00000135218 ENSG00000015520 ENSG00000113161 ENSG00000102967 ENSG00000084774 ENSG00000026103 PMC7773645__F1 NLRP3 inflammasome pathway associated with potential blockade sites of various pharmacological inhibitors to treat fibrosis ENSG00000162711 ENSG00000070444 ENSG00000135218 ENSG00000169047 ENSG00000198793 ENSG00000086991 ENSG00000136869 ENSG00000265972 PMC8392679__F3 Hidden Treasures: Macrophage Long Non-Coding RNAs in Lung Cancer Progression ENSG00000177575 ENSG00000154342 ENSG00000168036 ENSG00000107485 ENSG00000118520 ENSG00000196628 ENSG00000125967 PMC2118167__F7 Proposed model for the intersection of innate and adaptive immunity during polysaccharide-induced abscess formation in the peritoneal cavity ENSG00000138378 PMC7244458__F2 Mast cells (MCs) respond to a wide range of pathologic and environmental stimuli owing to the expression of toll-like receptors (TLRs), NOD-like receptors (NLRs), and RIG-1-like receptors (RLRs) ENSG00000163464 ENSG00000186810 ENSG00000033327 ENSG00000010810 ENSG00000183625 ENSG00000126353 ENSG00000164342 PMC10991391__F3 TGFB influences cellular metabolism through canonical and non-canonical pathways ENSG00000092621 ENSG00000198793 ENSG00000132170 PMC10991391__F5 Cellular metabolism and myofibroblast contraction cascades ENSG00000092621 ENSG00000198793 ENSG00000163914 PMC10991391__F2 Integrin receptors influence cellular metabolism through ECM sensing ENSG00000132109 ENSG00000198793 ENSG00000163914 ENSG00000134324 PMC8801022__F2 Mitophagy during oocyte aging in human, mouse, and Drosophila: implications for oocyte quality and mitochondrial disease ENSG00000158828 ENSG00000069509 ENSG00000171791 PMC7794837__F1 Altered Ca2+signaling in T cells during aging—impact of ion channel expression and function ENSG00000092439 ENSG00000291603 ENSG00000293604 ENSG00000049768 PMC3160099__F7 Pathways that control the onset of adulthood and the terminal differentiation of specific cell lineages are conserved from C ENSG00000168066 ENSG00000187772 PMC5496266__F6 The roles of microRNA families in hepatic fibrosis ENSG00000019991 PMC34619__F2 Signaling to eukaryotic translation initiation and elongation factors ENSG00000198793 ENSG00000284161 ENSG00000167658 PMC10141515__F6 Differentially expressed proteins of the serine metabolic pathway in ovarian cancer ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC10572723__F3 Interacting compounds and PTMs of PPARG that regulate its function in the endothelium ENSG00000150907 ENSG00000033800 ENSG00000168036 ENSG00000146648 PMC12017852__F5 Signaling pathways of RGS12 in tumor ENSG00000005810 ENSG00000130675 ENSG00000198793 ENSG00000159788 PMC12017852__F4 Relevant signaling pathways of RGS12 in arthritis ENSG00000159788 PMC5496266__F2 The roles of microRNA families in hepatic fibrosis ENSG00000145431 ENSG00000117020 PMC9030597__F1 Pathway-Based Genetic Score for Oxidative Stress: An Indicator of Host Vulnerability to Phthalate-Associated Adverse Neurodevelopment ENSG00000109320 ENSG00000086991 ENSG00000185591 ENSG00000140465 PMC8270011__F2 Lower Extremity Vein Dysfunction in Chronic Venous Disease and Implications in Management of Varicose Veins ENSG00000039537 ENSG00000166278 ENSG00000162692 PMC5504108__F2 Therapeutic targets that regulate YAP/Hippo activity in mesothelioma ENSG00000136807 ENSG00000186575 ENSG00000163914 ENSG00000067900 ENSG00000131023 PMC7938710__F3 Network analysis using the Ingenuity®Pathway Analysis (IPA®) software program ENSG00000132906 ENSG00000128310 ENSG00000074319 ENSG00000132478 ENSG00000146192 ENSG00000149295 ENSG00000104941 ENSG00000132671 ENSG00000173264 ENSG00000101850 ENSG00000069122 ENSG00000136872 ENSG00000127507 PMC8438004__F1 St8sia1-deficiency in mice alters tumor environments of gliomas, leading to reduced disease severity ENSG00000042832 ENSG00000131095 PMC3115327__F3 Scheme of the signal transduction pathway in response to DNA damage ENSG00000149311 ENSG00000164053 ENSG00000113456 ENSG00000116717 PMC4717889__F1 TLRs play critical roles in gastrointestinal inflammatory disorders at the mucosa ENSG00000174125 ENSG00000168036 ENSG00000185187 ENSG00000150455 ENSG00000069667 ENSG00000183735 ENSG00000239732 ENSG00000170458 ENSG00000177606 ENSG00000136869 ENSG00000172936 ENSG00000175104 ENSG00000146648 ENSG00000164342 PMC4598795__F6 Cd-elevated genes associated with mitochondrial oxidative phosphorylation pathway that occurs in electron transport system ENSG00000136521 ENSG00000119013 ENSG00000167985 PMC5982776__F4 The novel anti-androgen candidate galeterone targets deubiquitinating enzymes, USP12 and USP46, to control prostate cancer growth and survival ENSG00000152484 ENSG00000134438 ENSG00000109189 ENSG00000198793 ENSG00000197746 ENSG00000131095 ENSG00000196470 ENSG00000149311 ENSG00000175054 ENSG00000069482 ENSG00000112378 ENSG00000120868 ENSG00000026103 ENSG00000119125 PMC5245710__F6 Human SRMAtlas: A resource of targeted assays to quantify the complete human proteome ENSG00000137804 ENSG00000198830 ENSG00000131747 ENSG00000073111 ENSG00000198056 ENSG00000166508 ENSG00000276043 ENSG00000284320 ENSG00000137807 ENSG00000148773 ENSG00000109805 ENSG00000132646 ENSG00000167325 ENSG00000171848 ENSG00000100941 ENSG00000133119 ENSG00000116649 ENSG00000076382 ENSG00000253729 ENSG00000176619 PMC8431517__F4 Network Pharmacology Study on Morus alba L. Leaves: Pivotal Functions of Bioactives on RAS Signaling Pathway and Its Associated Target Proteins against Gout ENSG00000196839 ENSG00000088305 ENSG00000291803 ENSG00000122194 ENSG00000102967 ENSG00000069667 ENSG00000132170 ENSG00000183765 ENSG00000063176 ENSG00000188257 ENSG00000129214 ENSG00000291814 ENSG00000158825 ENSG00000136869 ENSG00000196689 ENSG00000176387 PMC3930975__F1 The unfolded protein response pathway ENSG00000128272 ENSG00000100219 PMC7793096__F3 Carbon monoxide-induced phenotypic switch of macrophages PMC8772992__F3 Preventive Effects of Beta-Cryptoxanthin, a Potent Antioxidant and Provitamin A Carotenoid, on Lifestyle-Related Diseases—A Central Focus on Its Effects on Non-Alcoholic Fatty Liver Disease (NAFLD) ENSG00000135437 ENSG00000184254 ENSG00000121207 ENSG00000284807 ENSG00000121039 ENSG00000128918 ENSG00000162496 ENSG00000248144 ENSG00000062282 ENSG00000095596 ENSG00000138207 ENSG00000003137 ENSG00000143320 ENSG00000198074 ENSG00000285482 ENSG00000187758 PMC4934035__F5 The pathway of LysoPC16:0 ENSG00000173599 ENSG00000198670 PMC5617461__F9 Overexpression of stathmin plays a pivotal role in the metastasis of esophageal squamous cell carcinoma ENSG00000213949 ENSG00000117228 ENSG00000177606 ENSG00000150093 ENSG00000186832 PMC3666557__F2 Endoplasmic Reticulum and the Unfolded Protein Response: Dynamics and Metabolic Integration ENSG00000128272 ENSG00000144895 PMC8269281__F1 Implications of Pruritogens in the Pathogenesis of Atopic Dermatitis ENSG00000137033 ENSG00000078747 ENSG00000145777 PMC11039397__GA1 StemRegenin 1 attenuates the RANKL-induced osteoclastogenesis via inhibiting AhR-c-src-NFKB/p-ERK MAPK-NFATc1 signaling pathway ENSG00000110711 ENSG00000147614 ENSG00000164935 ENSG00000102575 ENSG00000131196 ENSG00000106546 ENSG00000143387 PMC6001649__F2 Salivary Exosomes: Emerging Roles in Systemic Disease PMC7564398__F1 A high-fat diet (HFD) and chronic cannabidiol (CBD) administration on the sphingolipid metabolic pathway in rat myocytes ENSG00000063176 ENSG00000148154 PMC5846707__F1 Signal transduction by TGFBs and BMPs TGFB and BMP ligands induce formation of heteromeric complex between specific Type II and Type I receptors ENSG00000106683 ENSG00000163914 ENSG00000113360 PMC8614664__F2 Animal Models of Coenzyme Q Deficiency: Mechanistic and Translational Learnings ENSG00000132423 ENSG00000167113 ENSG00000123815 ENSG00000119723 ENSG00000175193 ENSG00000088682 ENSG00000148459 ENSG00000173085 ENSG00000167186 ENSG00000135469 PMC6041399__F1 Schematic presentation of JNK signaling pathway in cerebral ischemia/reperfusion injury ENSG00000002330 ENSG00000135116 ENSG00000026103 PMC3966557__F1 RGS proteins in the regulation of GPCR, PTH, and Wnt signaling pathways during bone remodeling ENSG00000152266 ENSG00000143248 ENSG00000150681 ENSG00000148908 ENSG00000168036 ENSG00000116741 ENSG00000036828 ENSG00000168646 ENSG00000131196 ENSG00000159788 PMC11657104__F1 Biosynthetic pathway of L-Homoserine in E ENSG00000122966 ENSG00000197487 PMC4803542__F1 Monogenic Mouse Models of Autism Spectrum Disorders: Common Mechanisms and Missing Links ENSG00000198576 PMC2808458__F2 Toll-like receptor signaling in cell proliferation and survival ENSG00000198793 ENSG00000172936 ENSG00000276561 PMC3827118__F2 Hh signaling in mammals ENSG00000128602 PMC2808458__F1 Toll-like receptor signaling in cell proliferation and survival ENSG00000183735 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC4414131__F2 Multiple cellular functions of the oncoprotein Golgi phosphoprotein 3 ENSG00000113384 ENSG00000147162 ENSG00000198793 ENSG00000069329 PMC3827118__F1 Wnt-dependent pathway responses ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000102312 ENSG00000168036 PMC12219892__F10 Pathways associated with DOX-induced cardiotoxicity ENSG00000198793 ENSG00000189403 ENSG00000096717 PMC7142847__F1 Metabolic reprogramming in triple-negative breast cancer (TNBC) ENSG00000180210 ENSG00000065833 ENSG00000092621 ENSG00000135069 ENSG00000070669 ENSG00000115419 ENSG00000013375 ENSG00000167701 PMC10141515__F5 Differentially expressed proteins of the glutamine metabolic pathway in ovarian cancer ENSG00000060982 ENSG00000115419 PMC5535862__F1 Schematic model proposing a differentiated cell as the cell of origin of skin squamous cell carcinoma (SCC) ENSG00000158055 ENSG00000198793 ENSG00000079432 PMC9240209__F2 Endless Wars: Severe Fever With Thrombocytopenia Syndrome Virus, Host Immune and Genetic Factors ENSG00000183735 ENSG00000088888 ENSG00000164342 PMC2945552__F11 Proposed signaling pathway modulated by TH2-3 in LPS-induced RAW264.7 cells ENSG00000170458 ENSG00000172936 ENSG00000113448 PMC6636823__F1 Canonical Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC7097090__F3 Counter-regulatory renin–angiotensin system in cardiovascular disease PMC10474042__F2 Calcium signaling in efferocytosis ENSG00000153208 ENSG00000167323 ENSG00000293604 ENSG00000156026 ENSG00000113851 PMC9502831__F1 Modulators of Wnt Signaling Pathway Implied in Dentin Pulp Complex Engineering: A Literature Review ENSG00000137834 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC7878452__F1 Glucose metabolism in the brain PMC8847181__F2 Functional and Therapeutic Significance of Tumor-Associated Macrophages in Colorectal Cancer ENSG00000164379 ENSG00000198793 ENSG00000173039 ENSG00000169429 ENSG00000073712 ENSG00000105639 ENSG00000168610 PMC4186533__F6 Src family kinases in Gq- and Gi-coupled receptor signaling ENSG00000010810 PMC8664592__F8 HSP27 Protein Dampens Encephalomyocarditis Virus Replication by Stabilizing Melanoma Differentiation-Associated Gene 5 ENSG00000183735 ENSG00000088888 PMC7552046__F6 Natural 5′ terminally deleted group-B enterovirus RNA forms can modulate type I interferon signaling pathway activation ENSG00000136457 ENSG00000088888 ENSG00000276561 ENSG00000142166 PMC7552046__F5 Group-B enterovirus proteinase activities impair type 1 signaling pathway activation in infected cells ENSG00000183735 ENSG00000088888 ENSG00000157625 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC7590177__F1 Detection of poxviruses by anti-viral pattern recognition receptors (PRRs) leads to the activation of IRFs ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000125538 ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000198933 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC7136464__F1 IFN-I and IFN-II signaling ENSG00000159128 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000027697 ENSG00000142166 PMC4157144__F3 L-Serine Biosynthesis PathwayDe novo biosynthesis of serine is crucial to provide the organism with sufficient levels of this amino acid ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC8199451__F1 Autophagy, Unfolded Protein Response, and Neuropilin-1 Cross-Talk in SARS-CoV-2 Infection: What Can Be Learned from Other Coronaviruses ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8042134__F3 Factors produced in the obese breast microenvironment contribute to the growth of breast cancer ENSG00000198793 ENSG00000168610 PMC6057142__F1 Wnt/Beta-catenin signing pathway ENSG00000281324 ENSG00000134982 ENSG00000168036 PMC6854528__F2 Model of the AhR signaling pathway ENSG00000140465 ENSG00000106546 PMC9163667__F2 Activation of Wnt/Beta-Catenin Signaling Pathway as a Promising Therapeutic Candidate for Cerebral Ischemia/Reperfusion Injury ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3690850__F7 Working model for rotavirus cell entry ENSG00000102189 ENSG00000070831 ENSG00000130402 PMC4256868__F7 Isoprenoid metabolism in photosynthetic plant cells and its relationship to photosynthesis, glycolysis, respiration, and photorespiration ENSG00000197429 ENSG00000062485 PMC5467707__F3 Pathway of Huntington’s disease enriched in target DEGs of DEmiRNAs of AD ENSG00000084093 ENSG00000130699 ENSG00000197386 ENSG00000120868 ENSG00000169375 ENSG00000164305 ENSG00000164087 PMC3923765__F2 BiNA: A Visual Analytics Tool for Biological Network Data ENSG00000149311 ENSG00000291983 ENSG00000002330 ENSG00000100906 ENSG00000109320 ENSG00000138794 ENSG00000120868 ENSG00000171791 ENSG00000006062 ENSG00000127191 ENSG00000164305 ENSG00000026103 PMC5467707__F4 Pathway of AD enriched in target DEGs of DEmiRNAs of AD ENSG00000132906 ENSG00000291983 ENSG00000142192 ENSG00000002330 ENSG00000133318 ENSG00000115310 ENSG00000120868 ENSG00000168040 ENSG00000119912 ENSG00000164305 PMC5045435__F2 Notch signaling: its roles and therapeutic potential in hematological malignancies ENSG00000148400 ENSG00000074181 PMC9523540__F3 Resveratrol: A potential therapeutic natural polyphenol for neurodegenerative diseases associated with mitochondrial dysfunction ENSG00000177169 ENSG00000156026 ENSG00000198793 ENSG00000096717 ENSG00000105227 ENSG00000106459 PMC6675305__F4 Genes enriched in the VS (shaded) are contained in the canonical pathway for Ras/MAPK signaling ENSG00000172680 ENSG00000002330 ENSG00000115415 ENSG00000291971 ENSG00000010810 ENSG00000254999 PMC6416842__F1 Simplified overview of one-carbon metabolism pathway ENSG00000124275 ENSG00000116984 PMC5664647__F1 Working Figure of the Angiogenesis Pathway Genes ENSG00000163464 ENSG00000105329 ENSG00000125538 ENSG00000169047 ENSG00000128052 ENSG00000122877 ENSG00000169429 ENSG00000146648 PMC6881465__F1 Animal cell cytokinesis ENSG00000198901 ENSG00000114346 ENSG00000166851 PMC8624911__F1 Macrophage Reprogramming and Cancer Therapeutics: Role of iNOS-Derived NO ENSG00000169245 ENSG00000260314 ENSG00000115415 ENSG00000137265 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC4530521__F1 Mini but Mighty - microRNAs in the Pathobiology of Periodontal Disease ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC4262777__F4 Tumor-derived exosomes are secreted via a constitutive/inducible pathway that can be activated by a p53-mediated response ENSG00000041353 ENSG00000026103 PMC4118469__F1 Molecular Mechanisms of Neurodegeneration in PD ENSG00000158828 ENSG00000283100 ENSG00000115317 PMC1351245__F1 Delayed Dark Adaptation in 11-cis-Retinol Dehydrogenase-deficient Mice ENSG00000135437 ENSG00000197713 PMC9441916__F5 Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy ENSG00000029363 ENSG00000163599 ENSG00000020633 ENSG00000197629 ENSG00000103522 ENSG00000110876 ENSG00000167780 ENSG00000019582 ENSG00000141867 ENSG00000226275 ENSG00000111537 ENSG00000130475 ENSG00000056558 ENSG00000074266 ENSG00000113263 ENSG00000125910 ENSG00000067955 ENSG00000073861 PMC2527618__F4 Graphic illustrating the roles of 8 genes implicated in the present study in lithium-sensitive signaling pathways ENSG00000167693 ENSG00000292149 ENSG00000168036 PMC4826168__F2 DAB2IP in cancer ENSG00000102871 ENSG00000291971 ENSG00000198793 ENSG00000136848 ENSG00000168036 PMC7746447__F2 TRPV2 regulation is involved in cellular responses relevant to cancer ENSG00000187688 PMC8415548__F5 Lipid Metabolism Regulates Oxidative Stress and Ferroptosis in RAS-Driven Cancers: A Perspective on Cancer Progression and Therapy ENSG00000151012 ENSG00000072274 ENSG00000197429 ENSG00000169710 ENSG00000168003 ENSG00000167468 ENSG00000167996 ENSG00000111371 ENSG00000136003 ENSG00000145354 ENSG00000115419 ENSG00000127948 ENSG00000123983 ENSG00000167419 PMC9316955__F2 Metabolic Plasticity of Tumor-Associated Macrophages in Shaping the Tumor Microenvironment Immunity ENSG00000125538 PMC6703955__F4 Proteostatic regulation of Ci/Gli proteinsAll Ci/Gli proteins, except mammalian Gli1, have an N-terminal repressor (R), a central zinc-figure (ZnF) and a C-terminal activator (A) domain ENSG00000121067 PMC10820833__F2 Cellular senescence pathways affected by Tax ENSG00000149311 ENSG00000175054 ENSG00000138385 PMC6703955__F1 Outlines of Hh signaling(A) In Drosophila, Ptc keeps Smo inactive, partly by promoting its internalization and degradation ENSG00000106571 ENSG00000166813 ENSG00000128602 PMC6563445__F2 The proposed mechanisms of IRF5 activation ENSG00000239732 ENSG00000167207 ENSG00000187796 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000159335 ENSG00000184216 PMC4858804__F7 Recycling and regulation of eIF2 by eIF2B ENSG00000100664 ENSG00000213626 PMC9563910__F1 Glucose 6-P Dehydrogenase—An Antioxidant Enzyme with Regulatory Functions in Skeletal Muscle during Exercise ENSG00000197713 PMC6859529__F5 Redox regulation of apoptosis under ER stress ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC6703304__F3 Schematic picture of the type I interferon production and different nucleic acid sensors ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000140968 ENSG00000163565 ENSG00000172936 ENSG00000175104 ENSG00000276561 PMC6859529__F3 UPR pathway under ER stress ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC6703304__F2 Inducers and regulators of IFNA production by plasmacytoid dendritic cell ENSG00000239732 ENSG00000134982 PMC10669635__F3 Partial epithelial to mesenchymal transition (p-EMT) and full EMT with associated biological markers ENSG00000170558 ENSG00000168036 PMC6703304__F1 Interferon receptors and signalling ENSG00000159128 ENSG00000111537 ENSG00000184995 ENSG00000105397 ENSG00000115415 ENSG00000027697 ENSG00000147896 ENSG00000142166 PMC10669635__F2 PI3K-Akt signalling pathway PMC9314177__F6 Cebpb Regulates Skeletal Stem Cell Osteogenic Differentiation and Fracture Healing via the WNT/Beta-Catenin Pathway ENSG00000172216 ENSG00000291837 ENSG00000167074 PMC4307112__F4 Differentially expressed genes in appetite control pathway between grass carp before and after food habit transition from transcriptome analysis ENSG00000184845 ENSG00000069482 ENSG00000100979 ENSG00000170893 ENSG00000115419 PMC3628402__F6 Splicing-factor oncoprotein SRSF1 stabilizes p53 via RPL5 and induces cellular senescence ENSG00000167325 ENSG00000171848 PMC4307112__F6 Differentially expressed genes in digestion and metabolism pathway between grass carp before and after food habit transition from transcriptome analysis ENSG00000141086 ENSG00000150907 ENSG00000087842 ENSG00000001626 ENSG00000104368 ENSG00000026103 PMC4858804__F1 Pathway for yeast cytoplasmic translation initiation ENSG00000100664 PMC4307112__F3 Differentially expressed genes in cell proliferation and differentiation pathway between grass carp before and after food habit transition from transcriptome analysis ENSG00000172680 ENSG00000138798 ENSG00000026103 PMC8864631__F7 Therapeutic siRNAs Targeting the JAK/STAT Signalling Pathway in Inflammatory Bowel Diseases ENSG00000111537 ENSG00000105639 PMC3317991__F6 RLIP76 Regulates PI3K/Akt Signaling and Chemo-Radiotherapy Resistance in Pancreatic Cancer ENSG00000135446 ENSG00000198793 ENSG00000171791 PMC5594453__F3 Signaling pathways that are activated by TMEM16A in cancer ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC1395315__F1 Methionine-Homocysteine metabolism and related pathways ENSG00000228716 ENSG00000156110 ENSG00000136371 ENSG00000124275 ENSG00000099810 ENSG00000116761 PMC4482759__F3 From pathways to networks: connecting dots by establishing protein-protein interaction networks in signaling pathways using affinity purification and mass spectrometry ENSG00000082397 ENSG00000134982 ENSG00000167005 ENSG00000198265 ENSG00000169032 ENSG00000166851 ENSG00000153107 ENSG00000116161 ENSG00000166263 ENSG00000186575 ENSG00000074800 ENSG00000163558 ENSG00000113558 ENSG00000132383 ENSG00000170921 ENSG00000136153 ENSG00000129474 ENSG00000113645 ENSG00000101901 ENSG00000168807 ENSG00000106066 ENSG00000126016 ENSG00000110711 ENSG00000111605 ENSG00000175793 ENSG00000138029 ENSG00000122966 ENSG00000197905 ENSG00000007866 ENSG00000150457 ENSG00000160410 ENSG00000197694 ENSG00000131023 ENSG00000074219 ENSG00000116641 ENSG00000240303 ENSG00000090273 ENSG00000196961 ENSG00000196365 PMC4158839__F2 The development of the auditory sense organ ENSG00000136158 ENSG00000004975 ENSG00000135547 ENSG00000104290 PMC5833124__F1 CX3CR1-CX3CL1 signaling pathway and migration process of immune cells via their interactions ENSG00000163464 ENSG00000203710 ENSG00000137845 PMC6352210__F4 Internalization and cellular trafficking of FGFRs ENSG00000066468 ENSG00000160867 ENSG00000291971 ENSG00000149269 ENSG00000077782 PMC2234347__F2 CNX/CRT cycle ENSG00000116406 ENSG00000088298 ENSG00000135506 PMC4766407__F7 Specific regulation of PRMT1 expression by PIAS1 and RKIP in BEAS-2B epithelia cells and HFL-1 fibroblasts in lung inflammation ENSG00000125538 ENSG00000126457 ENSG00000172936 ENSG00000175104 ENSG00000115594 PMC4963347__F2 Schematic representation of de novo and salvage pathways for NAD+ biosynthesis ENSG00000105835 ENSG00000123572 PMC1395315__F5 Elevated Homocysteine is associated with atherosclerosis ENSG00000135218 ENSG00000113161 ENSG00000100985 PMC6363996__F7 Model summarizing the inhibition of the cGAS-STING pathway by MDV VP23 ENSG00000183735 ENSG00000164430 ENSG00000276561 PMC11731210__F10 Work model ENSG00000165891 ENSG00000101057 ENSG00000145321 PMC7605163__F6 TGFB Promotes Metabolic Reprogramming in Lung Fibroblasts via mTORC1-dependent ATF4 Activation ENSG00000128272 ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC9658487__F5 Hallmarks of Cancer Expression in Oral Lichen Planus: A Scoping Review of Systematic Reviews and Meta-Analyses ENSG00000198793 PMC3694890__F8 Novel Phosphopeptide Microarray Based Interactome Map in Breast Cancer Cells Reveals Phosphoprotein-GRB2 Cell Signaling Networks ENSG00000291603 ENSG00000119535 ENSG00000085514 ENSG00000291971 ENSG00000169047 ENSG00000115904 ENSG00000187266 ENSG00000168610 ENSG00000141968 ENSG00000160691 ENSG00000179295 ENSG00000122025 ENSG00000122188 ENSG00000213658 ENSG00000010810 ENSG00000133124 ENSG00000124181 ENSG00000146648 PMC8373148__F7 Towards a global investigation of transcriptomic signatures through co-expression networks and pathway knowledge for the identification of disease mechanisms ENSG00000128272 ENSG00000152495 PMC9415972__F1 Harnessing Immune Evasion Strategy of Lymphatic Filariae: A Therapeutic Approach against Inflammatory and Infective Pathology ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC8745448__F1 Lipid-Induced Adaptations of the Pancreatic Beta-Cell to Glucotoxic Conditions Sustain Insulin Secretion ENSG00000163686 ENSG00000135218 ENSG00000291507 ENSG00000126266 ENSG00000198670 PMC5713354__F2 Current possible strategies to bypass AVPR2 mutations responsible for X-linked NDI ENSG00000167580 ENSG00000126895 ENSG00000146648 ENSG00000274473 PMC8621388__F1 Cell Behavior of Non-Small Cell Lung Cancer Is at EGFR and MicroRNAs Hands ENSG00000198793 ENSG00000168040 ENSG00000168610 ENSG00000146648 ENSG00000159399 PMC10378552__F2 Exploring the Molecular Complexity of Medulloblastoma: Implications for Diagnosis and Treatment ENSG00000198793 ENSG00000164690 ENSG00000128602 PMC6859529__F7 Redox regulation of IRE1A to control UPR ENSG00000100219 ENSG00000127191 PMC11360082__F2 Catechol estrogens synthesis pathway in humans and the possible homologs identified in schistosome species ENSG00000108786 ENSG00000140505 ENSG00000140465 PMC9162805__F3 IKKE in the Metabolic Diseases: Physiology, Pathophysiology, and Pharmacology ENSG00000276561 PMC8377231__F1 Mechanisms and Boundary Conditions of Drug Memory Reconsolidation ENSG00000128272 ENSG00000144895 PMC12104430__F7 The OMD-induced regulation in hDPSCs upon LPS stimulation ENSG00000162711 ENSG00000291355 ENSG00000115594 PMC9243319__F1 Revisiting chemoresistance in ovarian cancer: Mechanism, biomarkers, and precision medicine ENSG00000143799 ENSG00000291803 ENSG00000227345 PMC8729140__F8 Adiponectin triggers breast cancer cell death via fatty acid metabolic reprogramming ENSG00000159346 ENSG00000285070 ENSG00000096717 ENSG00000026103 PMC4484411__F1 Genetic/molecular alterations of meningiomas and the signaling pathways targeted ENSG00000186575 ENSG00000135446 ENSG00000138798 ENSG00000198793 ENSG00000105810 ENSG00000124181 ENSG00000168610 ENSG00000139687 PMC6005538__F6 Plasmatic membrane toll-like receptor expressions in human astrocytomas ENSG00000172936 ENSG00000150455 PMC7534289__F1 Two-Signal Models of Costimulatory and Inhibitory Pathways PMC5743771__F1 Challenges and Promise of Targeting the Liver X Receptors for Treatment of Inflammatory Disease ENSG00000162711 ENSG00000115415 ENSG00000033800 ENSG00000160179 ENSG00000116030 ENSG00000125347 ENSG00000188612 ENSG00000288325 PMC5743771__F2 Challenges and Promise of Targeting the Liver X Receptors for Treatment of Inflammatory Disease ENSG00000138075 ENSG00000130164 ENSG00000042832 ENSG00000015520 ENSG00000160179 ENSG00000143921 ENSG00000026103 PMC4979589__F7 MUC4 is negatively regulated through the Wnt/Beta-catenin pathway via the Notch effector Hath1 in colorectal cancer ENSG00000134982 ENSG00000168036 ENSG00000114315 ENSG00000145113 PMC9300463__F2 Expression analysis of candidate genes in S. nux-vomica (strychnine producer) and Strychnos sp. (diaboline producer) ENSG00000169682 ENSG00000183018 PMC4621423__F2 Schematic diagram that gintonin-mediated in vitro cellular effects through LPA receptors in neurons and astrocytes is linked to in vivo pharmacological effects ENSG00000087085 ENSG00000198670 PMC5660607__F7 Crosstalk of KDG molecular and network pathways ENSG00000123338 ENSG00000162711 ENSG00000146094 ENSG00000115904 ENSG00000172936 ENSG00000136869 ENSG00000213523 PMC6157710__F1 Directing the use of DDR kinase inhibitors in cancer treatment ENSG00000012061 ENSG00000164053 ENSG00000198793 ENSG00000181555 ENSG00000136807 ENSG00000117713 ENSG00000149311 ENSG00000175054 ENSG00000276618 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000128602 PMC3674242__F7 Proteolysis of MOB1 by the ubiquitin ligase praja2 attenuates Hippo signalling and supports glioblastoma growth ENSG00000150457 ENSG00000131023 PMC11612265__F3 Glycolytic reprogramming in macrophages orchestrates NLRP3 inflammasome activation in ALI/ARDS ENSG00000180210 ENSG00000162711 PMC7461872__F3 Fve-type FIPs on the immune system, adapted from Hsu et al ENSG00000291971 ENSG00000134982 ENSG00000112149 PMC6429113__F8 Proposed model for role of MARK4 in regulating lipogenesis in pig placental trophoblast cells ENSG00000168036 ENSG00000007047 PMC11612265__F1 Possible activation mechanism of NLRP3 inflammasome ENSG00000278718 ENSG00000162711 ENSG00000088888 ENSG00000136869 ENSG00000168040 PMC2887259__F5 Signaling cascades that regulate A ENSG00000033327 ENSG00000010810 ENSG00000146469 ENSG00000169047 ENSG00000168398 ENSG00000127191 ENSG00000165646 PMC6653805__F6 Autophagy in Adipose Tissue Physiology and Pathophysiology ENSG00000162711 ENSG00000125538 ENSG00000005893 ENSG00000136869 ENSG00000145782 ENSG00000057663 PMC7655160__F8 Graphical model displaying the mechanisms of ARHGEF11 in regulating cell cycle and EMT via activating Beta-catenin ENSG00000168036 PMC3339894__F2 Putative molecular mechanisms of Wnt signaling, lipid metabolism, and IL-6 effects on insulin signaling in nonobese PCOS adipose tissue ENSG00000042832 ENSG00000134982 ENSG00000169047 ENSG00000177606 ENSG00000026508 ENSG00000168036 ENSG00000079435 ENSG00000168610 PMC7759910__F2 SRC kinase during platelet activation ENSG00000197943 ENSG00000137076 ENSG00000089159 PMC3218922__F6 Pathway generated by ingenuity pathway analysis with proteins identified as specific target antigens ENSG00000182718 ENSG00000109814 ENSG00000160789 ENSG00000178035 ENSG00000074800 ENSG00000181163 ENSG00000089157 ENSG00000113520 ENSG00000187764 ENSG00000138668 ENSG00000092820 PMC7858073__F5 Signaling and molecular network mapping of genes differentially expressed in the ileal transcriptome of NCFM-colonized versus germfree mice (24 genes) using the Ingenuity Pathway Analysis software ENSG00000133105 ENSG00000105516 ENSG00000140279 ENSG00000274736 ENSG00000110324 ENSG00000140274 ENSG00000248099 ENSG00000147697 ENSG00000125995 ENSG00000168062 ENSG00000103018 ENSG00000111537 ENSG00000188167 ENSG00000162949 ENSG00000124508 ENSG00000136997 ENSG00000108700 ENSG00000168924 ENSG00000186912 ENSG00000176358 ENSG00000144559 PMC10837142__F5 Terpenoid biosynthesis pathway in T ENSG00000152904 ENSG00000104549 ENSG00000167508 PMC10837142__F7 Peroxisome biogenesis pathway in T ENSG00000142655 ENSG00000176894 ENSG00000124587 ENSG00000288217 ENSG00000157911 ENSG00000101417 ENSG00000108733 ENSG00000150787 ENSG00000164751 ENSG00000162928 ENSG00000034693 ENSG00000121680 PMC10837142__F6 Common symbiosis signalling pathway in T ENSG00000113456 ENSG00000125450 ENSG00000069248 PMC8861971__F7 An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer ENSG00000135446 ENSG00000123374 ENSG00000139687 PMC7646582__F1 Diagram illustrating the diagnostic features of cutaneous melanoma and uveal melanoma ENSG00000163930 ENSG00000157404 ENSG00000115524 ENSG00000173674 ENSG00000088256 ENSG00000101333 PMC11724797__F17 KEGG NF-kappa B signaling pathway—Homo sapiens (human) ENSG00000242689 ENSG00000102871 ENSG00000138798 ENSG00000150455 ENSG00000095585 ENSG00000149311 ENSG00000226275 ENSG00000213658 ENSG00000135960 ENSG00000170458 ENSG00000186716 ENSG00000136869 ENSG00000172936 ENSG00000083799 ENSG00000175104 ENSG00000121060 PMC5837819__F2 CK1 in Developmental signaling: Hedgehog and Wnt ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000128602 PMC12008652__F7 Application of biodegradable implants in pediatric orthopedics: shifting from absorbable polymers to biodegradable metals ENSG00000152266 ENSG00000170365 ENSG00000092439 PMC9521521__F2 Deciphering the role of transforming growth factor-beta 1 as a diagnostic-prognostic-therapeutic candidate against hepatocellular carcinoma ENSG00000198793 PMC12008652__F5 Cellular and molecular mechanisms revealing the potential effects of magnesium ions on bone repair ENSG00000092439 ENSG00000281324 ENSG00000162337 ENSG00000102158 ENSG00000291837 ENSG00000136869 ENSG00000175104 ENSG00000131196 ENSG00000143387 PMC9120647__AF1 20 (S)-ginsenoside Rh2 inhibits colorectal cancer cell growth by suppressing the Axl signaling pathway in vitro and in vivo ENSG00000167601 ENSG00000291971 ENSG00000198793 PMC10495745__F4 Activation of MAPK and TGF‐B‐SMAD signaling pathways in macrophages ENSG00000138798 ENSG00000146648 PMC10953212__F4 Relationship between inflammation and NASH disease progression ENSG00000162711 ENSG00000168610 PMC6381062__F2 A working model of NPR1, NPR3, and NPR4 ENSG00000184900 PMC10495745__F3 Activation of PI3K/Akt and Notch signaling pathways in macrophages ENSG00000008710 ENSG00000168214 ENSG00000283780 ENSG00000150907 PMC10953212__F2 Glucose–insulin signaling pathway ENSG00000150907 ENSG00000084734 ENSG00000197594 ENSG00000169047 ENSG00000169710 PMC10495745__F2 Activation of the JAK‐STAT signaling pathway in macrophages ENSG00000213928 ENSG00000105397 PMC5133678__F14 ‘Apoptotic execution phase’ gene enrichment in cisplatin-treated samples ENSG00000182568 ENSG00000092853 ENSG00000189403 ENSG00000164104 PMC7277093__F1 Role of CBS and other enzymes in the regulation of mammalian sulfur amino acid metabolism ENSG00000116761 PMC10495745__F1 Activation of the NF‐KB signaling pathway in macrophages ENSG00000183735 ENSG00000102871 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000168040 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC10953212__F1 Lipid metabolism in NAFLD ENSG00000213996 ENSG00000135218 ENSG00000170509 ENSG00000138823 ENSG00000100344 ENSG00000198670 ENSG00000273592 PMC9510030__F1 Molecular inhibition of RAS signalling to target ageing and age-related health ENSG00000169047 PMC10495745__F5 Activation of GPCR signaling pathway in macrophages ENSG00000108691 ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000115415 ENSG00000134982 ENSG00000168610 PMC9456310__F7 SP and KLF Transcription Factors in Cancer Metabolism ENSG00000109814 ENSG00000198901 ENSG00000119138 ENSG00000185591 ENSG00000073756 PMC9456310__F6 SP and KLF Transcription Factors in Cancer Metabolism ENSG00000147162 ENSG00000067057 ENSG00000102349 ENSG00000185591 ENSG00000136826 PMC8429580__F2 NLRP3 inflammasome activation and cell death ENSG00000278718 ENSG00000162711 ENSG00000102871 ENSG00000082512 ENSG00000172936 ENSG00000136869 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC4556964__F4 Frankincense and myrrh suppress inflammation via regulation of the metabolic profiling and the MAPK signaling pathway ENSG00000173599 ENSG00000198670 PMC3311515__F1 Scheme for the intracellular renal RAS on the nuclear membrane ENSG00000130234 PMC11171484__F4 Systemic inhibition of TGFB signaling in the fibrotic lung by pirfenidone and localized inhibition of TGFB signaling in the fibrotic niche by bexotegrast (A,B) ENSG00000164932 ENSG00000291748 PMC8997969__F2 Metabolic Reprogramming and Its Relationship to Survival in Hepatocellular Carcinoma ENSG00000131473 ENSG00000148926 ENSG00000173599 ENSG00000198670 PMC1963416__F1 Signaling mechanisms for the activation of HAT and HDAC ENSG00000147099 ENSG00000196591 PMC8525887__F1 Schematic showing regulation of PAI-1 activation and its role in hepatocytes ENSG00000119888 ENSG00000136997 ENSG00000122194 PMC8087647__F3 autophagy in immune cells in the tumour microenvironment ENSG00000177169 ENSG00000081181 ENSG00000123395 ENSG00000136997 ENSG00000079432 ENSG00000118520 ENSG00000171791 ENSG00000049768 ENSG00000123908 PMC8087647__F2 Impact of tumour autonomous autophagy on immunity ENSG00000169245 ENSG00000188554 ENSG00000107562 ENSG00000163568 ENSG00000138755 PMC7247521__F6 Component-target-pathway-disease network ENSG00000188822 ENSG00000125384 ENSG00000143839 ENSG00000107036 ENSG00000167780 ENSG00000149295 ENSG00000131730 ENSG00000065833 ENSG00000223572 ENSG00000082175 ENSG00000138823 ENSG00000134824 ENSG00000158874 ENSG00000127948 ENSG00000162896 PMC8699356__F1 Interleukin (IL)-9 Supports the Tumor-Promoting Environment of Chronic Lymphocytic Leukemia ENSG00000002330 ENSG00000115415 ENSG00000169047 ENSG00000105639 ENSG00000168610 PMC4488505__F5 Dendritic Cell-Mediated Phagocytosis but Not Immune Activation Is Enhanced by Plasmin ENSG00000120833 ENSG00000181163 ENSG00000291971 ENSG00000198793 ENSG00000108443 ENSG00000100526 ENSG00000171791 ENSG00000169032 ENSG00000166484 ENSG00000102010 ENSG00000120899 ENSG00000177606 ENSG00000204673 ENSG00000123374 PMC8087647__F1 Machinery of canonical and non-canonical autophagy ENSG00000177169 ENSG00000110497 ENSG00000123395 ENSG00000198382 ENSG00000126775 ENSG00000144848 ENSG00000157954 ENSG00000145782 PMC8429580__F1 NLRP3 inflammasome activation and cell death ENSG00000278718 ENSG00000162711 ENSG00000172936 ENSG00000136869 ENSG00000168040 PMC3858477__F4 Transcriptomics of Glucocorticoid Receptor Signaling in Developing Zebrafish ENSG00000147649 ENSG00000149573 ENSG00000105401 ENSG00000127528 ENSG00000103241 ENSG00000157184 ENSG00000066583 ENSG00000134086 ENSG00000144554 ENSG00000139515 ENSG00000113430 ENSG00000163497 ENSG00000112182 ENSG00000170549 ENSG00000077782 ENSG00000062485 ENSG00000282830 ENSG00000136535 ENSG00000171385 ENSG00000115392 ENSG00000148843 ENSG00000131095 ENSG00000137880 ENSG00000103034 ENSG00000115648 ENSG00000139287 ENSG00000172602 ENSG00000115263 ENSG00000205927 ENSG00000166224 ENSG00000073578 ENSG00000135111 ENSG00000136630 ENSG00000117525 ENSG00000109861 ENSG00000160588 ENSG00000148798 ENSG00000115041 ENSG00000175832 ENSG00000121053 ENSG00000091482 ENSG00000024422 ENSG00000136158 ENSG00000168438 ENSG00000145708 ENSG00000170561 ENSG00000074695 ENSG00000100060 ENSG00000184916 ENSG00000168610 ENSG00000139352 ENSG00000016082 ENSG00000113328 ENSG00000277586 ENSG00000132872 ENSG00000153944 ENSG00000123892 ENSG00000186716 ENSG00000172346 ENSG00000114315 PMC3952878__F4 FAK functions in cancer stem cells ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000136997 ENSG00000026508 ENSG00000168036 ENSG00000164690 PMC3313462__F4 Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes ENSG00000160214 ENSG00000159399 PMC4964743__F3 Regulation of HER3 and downstream signaling ENSG00000069869 ENSG00000198793 PMC12217143__F7 TgFLP12 function in Toxoplasma gondii lipid metabolism ENSG00000011007 ENSG00000198670 ENSG00000154582 PMC5865879__F1 Chemokine signaling pathway significantly enriched in differentially expressed genes ENSG00000169291 ENSG00000124126 PMC8888875__F2 Indole-Based Small Molecules as Potential Therapeutic Agents for the Treatment of Fibrosis ENSG00000111537 ENSG00000178573 ENSG00000134982 ENSG00000125538 ENSG00000291748 ENSG00000168036 ENSG00000108821 ENSG00000079999 PMC4800799__F7 Model depicting the proposed effect of starvation on microRNA in cancer cells ENSG00000129219 ENSG00000173599 PMC5556034__F6 Simplified scheme of the enzymes and transcription factors involved in de novo lipogenesis pathway ENSG00000170522 ENSG00000169710 PMC4403007__F3 Intricacies of cardiac damage in coxsackievirus B3 infection: Implications for therapy ENSG00000164342 PMC4725058__F2 Length of interaction alters the activation of specific transcription factors ENSG00000291603 ENSG00000213658 ENSG00000070831 ENSG00000167323 ENSG00000177606 ENSG00000132478 PMC6689553__F4 Proposed metabolic pathway of the relevant eicosanoids ENSG00000161905 ENSG00000167468 PMC8873175__F1 Therapeutic Potential of Glutamine Pathway in Lung Cancer ENSG00000167005 ENSG00000127528 ENSG00000102967 ENSG00000115419 ENSG00000188338 PMC12015589__F7 Schematic diagram illustrating the beneficial effects of IL-7 during porcine early embryonic development PMC6387269__F3 For using mTOR in PD treatment ENSG00000198793 PMC8964978__F1 IL-6/JAK/STAT3 Signaling in Breast Cancer Metastasis: Biology and Treatment ENSG00000137845 ENSG00000168610 PMC4618674__F2 Global Gene Expression Profiling in Omental Adipose Tissue of Morbidly Obese Diabetic African Americans ENSG00000105722 ENSG00000132604 ENSG00000070831 ENSG00000163914 ENSG00000127948 PMC3435478__F2 Age-related alterations in receptors and signaling molecules of CD8 T cells ENSG00000139193 ENSG00000168685 PMC8872633__F4 Protein cysteine palmitoylation in immunity and inflammation ENSG00000291603 ENSG00000213658 ENSG00000113263 ENSG00000124181 PMC5182094__F2 Biosynthetic pathway connects cryptic ribosomally synthesized posttranslationally modified peptide genes with pyrroloquinoline alkaloids ENSG00000084110 ENSG00000145020 PMC6559733__F1 Hypothesized therapeutic role of blocking IL6 pathway in Sarcoidosis ENSG00000111537 ENSG00000198793 PMC7412712__F2 Schematic description of TRAIL signaling cascade and interaction of lncRNA ENSG00000198914 ENSG00000100290 ENSG00000120868 ENSG00000171791 ENSG00000168040 PMC3998825__F1 Alternatively Activated Macrophages Revisited: New Insights into the Regulation of Immunity, Inflammation and Metabolic Function following Parasite Infection ENSG00000137033 ENSG00000137265 ENSG00000131724 ENSG00000103522 ENSG00000136826 PMC3263596__F3 TGFB pathway in NetSlim ENSG00000262406 ENSG00000157933 ENSG00000041982 ENSG00000070831 ENSG00000078747 ENSG00000134982 ENSG00000164362 ENSG00000067900 ENSG00000182759 PMC6947814__F3 Regulatory roles of cellular IRES trans-acting factors (ITAFs) in EV-A71 translation ENSG00000130957 PMC3772106__F1 How are STAT1 and cholesterol metabolism associated in antiviral responses? ENSG00000138135 ENSG00000115415 ENSG00000164342 PMC10540347__F10 SQLE Knockdown inhibits bladder cancer progression by regulating the PTEN/AKT/GSK3B signaling pathway through P53 ENSG00000104549 PMC7756907__F1 One ring to bring them all and in the darkness bind them: The Trafficking of Heme without Deliverers. ENSG00000177575 ENSG00000119686 ENSG00000118777 PMC8992556__F1 Intracrine androgen biosynthesis and drug resistance ENSG00000086696 ENSG00000151632 ENSG00000133835 ENSG00000203857 PMC7023715__F7 Activation of the PDGFRAlpha-Nrf2 anti-adipogenic signaling pathway impairs adipocyte differentiation in Nck1-deficient BM-MSCs ENSG00000134853 PMC7381711__F3 Summary of potential therapeutic effects of heparin in coronavirus disease 2019 (COVID-19) ENSG00000003436 ENSG00000134982 ENSG00000130234 PMC6429018__F8 Knockdown of PCAT-1 inhibited cell proliferation, metastasis, and promoted cell apoptosis in ECC cell lines ENSG00000168036 ENSG00000125084 PMC3584589__F9 Two mechanisms by which miR-200a regulates the activity of Beta-catenin ENSG00000169554 ENSG00000168036 PMC4872787__F6 IL-32θ inhibits stemness and epithelial-mesenchymal transition of cancer stem cells via the STAT3 pathway in colon cancer ENSG00000168283 ENSG00000168610 PMC3338086__F1 Canonical and non canonical NF-kB pathways and related drugs inhibition ENSG00000104856 ENSG00000186716 ENSG00000173039 PMC3068560__F4 Proteome of sickle cell disease: insights from exploratory proteomic profiling ENSG00000120438 ENSG00000122194 ENSG00000166128 PMC7836100__F2 Structural changes capture multiple regulatory events in yeast responding to osmotic shockA schematic of the yeast HOG-MAPK pathway and its links to glycolytic and glycerol biosynthesis pathways ENSG00000180210 PMC7255347__F1 Type I and Type III Interferons – Induction, Signaling, Evasion, and Application to Combat COVID-19 ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000185885 ENSG00000172936 ENSG00000136869 ENSG00000135828 ENSG00000125347 ENSG00000276561 ENSG00000164342 PMC3877020__F4 UVA and UVB Irradiation Differentially Regulate microRNA Expression in Human Primary Keratinocytes ENSG00000143878 ENSG00000143126 ENSG00000124275 ENSG00000100985 ENSG00000106628 ENSG00000146701 PMC5220330__F1 Interleukin-33 (IL-33)/ST2 signaling pathway ENSG00000137033 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC2817430__F1 Phylogenomics of Sterol Synthesis: Insights into the Origin, Evolution, and Diversity of a Key Eukaryotic Feature ENSG00000116133 ENSG00000172893 ENSG00000149809 ENSG00000197429 PMC2278091__F1 F igure 1.— ENSG00000134086 ENSG00000291971 ENSG00000163914 ENSG00000198576 ENSG00000168036 ENSG00000146648 PMC7246871__F5 Closer examination of all drugs and pathways associated with the gene TNF ENSG00000186575 ENSG00000011422 ENSG00000082175 ENSG00000132170 PMC5454339__F3 Suppression of BCR signaling is detrimental to growth and sensitizes B-ALL to dex ENSG00000071564 ENSG00000198793 ENSG00000105647 ENSG00000081189 ENSG00000126458 ENSG00000010671 ENSG00000168685 PMC8781679__F2 An Updated Review on the Modulation of Carbon Partitioning and Allocation in Arbuscular Mycorrhizal Plants ENSG00000026103 PMC9667637__F3 Neutrophil extracellular traps in cancer progression, metastasis and therapy ENSG00000163464 ENSG00000239732 ENSG00000136869 ENSG00000005381 PMC11822647__F8 Schematic image shows the role of neuronal CTSS in the process of aging and Alzheimer's disease (AD) ENSG00000168329 ENSG00000163131 ENSG00000168610 PMC5585150__F1 Pro- and antitumoral effects of tumor-immune cell heterotypic GJICs PMC7140419__F4 Main signaling pathways playing role in autophagy activation ENSG00000123395 ENSG00000198793 ENSG00000096717 PMC9667637__F2 Neutrophil extracellular traps in cancer progression, metastasis and therapy ENSG00000239732 ENSG00000147419 ENSG00000136869 PMC8040471__F7 Proposed model of PAK5-AIF signaling pathway in breast cancer proliferation ENSG00000171791 PMC7330710__F1 Representation of some of the metabolic adaptation and reprogramming of cancer stem cells ENSG00000125166 ENSG00000169710 PMC5514546__F2 KEAP1-NRF2 Signaling and Autophagy in Protection against Oxidative and Reductive Proteotoxicity ENSG00000152348 ENSG00000144848 ENSG00000189403 PMC2990540__F1 APC/C inhibition is regulated by signalling within the cytoplasm (a) and at the kinetochore (b) ENSG00000137812 ENSG00000171444 ENSG00000117399 ENSG00000108106 PMC9694162__F6 PI3K/Akt-Mediated Nrf2/HO-1 Signaling Pathway in Resveratrol Alleviation of Zearalenone-Induced Oxidative Stress and Apoptosis in TM4 Cells ENSG00000171791 ENSG00000079999 PMC8889620__F2 Involvement of LDL and ox-LDL in Cancer Development and Its Therapeutical Potential ENSG00000130164 ENSG00000198793 ENSG00000100985 ENSG00000168610 ENSG00000150637 ENSG00000128536 PMC9114649__F3 Influence of Arginine Methylation in Immunity and Inflammation ENSG00000169248 ENSG00000169245 ENSG00000100906 ENSG00000125538 ENSG00000056558 ENSG00000115009 PMC9457753__F2 Lipopolysaccharide-Induced Model of Neuroinflammation: Mechanisms of Action, Research Application and Future Directions for Its Use ENSG00000162711 ENSG00000104321 ENSG00000170458 ENSG00000172005 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000127666 ENSG00000276561 ENSG00000196689 PMC9114649__F2 Influence of Arginine Methylation in Immunity and Inflammation ENSG00000100906 ENSG00000134982 ENSG00000126457 ENSG00000277263 PMC2897958__F4 Regulation of Lipid and Glucose Metabolism by Phosphatidylcholine Transfer Protein ENSG00000157184 ENSG00000042832 PMC5797008__F5 Activation of MAPK signalling results in resistance to saracatinib (AZD0530) in ovarian cancer ENSG00000291971 ENSG00000196712 PMC9114649__F4 Influence of Arginine Methylation in Immunity and Inflammation ENSG00000169245 ENSG00000142453 ENSG00000126457 ENSG00000185745 ENSG00000132600 ENSG00000049768 ENSG00000276561 PMC4115244__F3 Pak Signaling in the Development and Progression of Cancer ENSG00000002330 ENSG00000070831 ENSG00000136997 PMC1553197__F8 Model of CISK-mediated inhibition of CXCR4 sorting and degradation ENSG00000124102 ENSG00000107562 ENSG00000121966 PMC6208316__F2 Analysis of pathways responsible for the expression of TGFB target genes ENSG00000125735 ENSG00000112715 ENSG00000164305 ENSG00000115607 ENSG00000115602 ENSG00000122223 ENSG00000198742 ENSG00000177606 ENSG00000134070 ENSG00000172936 ENSG00000173846 ENSG00000175104 ENSG00000184216 ENSG00000086730 ENSG00000026103 PMC9105177__F2 Roles of Ubiquitination in Pathogenesis of Influenza Virus Infection ENSG00000183735 ENSG00000088888 ENSG00000121060 PMC7471650__F1 Signaling pathways underlying Sirt3-mediated regulation of autophagy ENSG00000198793 ENSG00000142082 PMC5539950__F1 Oxidative estrogen metabolism causes DNA adduct formation ENSG00000140465 PMC4758903__F1 MicroRNA-based Therapeutic Strategies for Targeting Mutant and Wild Type RAS in Cancer ENSG00000164056 ENSG00000166068 ENSG00000196712 PMC8351592__F2 Type I Interferon Induction in Cutaneous DNA Damage Syndromes ENSG00000164430 PMC9367737__F2 Crucial Roles of Bmi-1 in Cancer: Implications in Pathogenesis, Metastasis, Drug Resistance, and Targeted Therapies ENSG00000168283 ENSG00000135446 ENSG00000105810 PMC9448891__F6 Toll-like receptor signaling pathway triggered by inhibition of serpin A1 stimulates production of inflammatory cytokines by endometrial stromal cells ENSG00000115415 ENSG00000125538 ENSG00000169429 ENSG00000172936 ENSG00000136869 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC2358943__F1 Metabolism of PtdIns(4,5)P2 by PLCG and PI3K ENSG00000124102 ENSG00000198793 ENSG00000135605 PMC9222172__F3 Good and the Bad: Monocytes’ and Macrophages’ Diverse Functions in Inflammation ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000168610 PMC9470863__F1 Toxoplasma gondii infection possibly reverses host immunosuppression to restrain tumor growth ENSG00000172936 PMC8600858__F4 Transcriptome provides potential insights into how calcium affects the formation of stone cell in Pyrus ENSG00000105722 ENSG00000084774 PMC9569901__F1 Genome-Wide Identification, Characterization and Expression Analysis of Toll-like Receptors in Marbled Rockfish (Sebastiscus marmoratus) ENSG00000239732 ENSG00000170458 ENSG00000172936 ENSG00000131323 ENSG00000150455 ENSG00000164342 ENSG00000143387 PMC6289770__F3 The lipoyl relay pathway of lipoyl-protein assembly.A ENSG00000107798 ENSG00000188992 ENSG00000079435 ENSG00000173239 PMC8120713__F4 Functional conservation in genes and pathways linking ageing and immunity ENSG00000107779 ENSG00000170365 ENSG00000088826 ENSG00000123612 ENSG00000135503 ENSG00000146648 PMC4055924__F6 CD28 signaling in myeloma cells PMC6478827__F6 Cell cycle regulation in GCs of small follicles ENSG00000198793 ENSG00000136997 ENSG00000118971 PMC11607693__F1 Genome engineering Drosophila TGFB/BMP signaling ENSG00000113140 ENSG00000100304 PMC10945329__F13 MSC-EV effect on bone regeneration ENSG00000178860 ENSG00000152266 ENSG00000154342 ENSG00000162711 ENSG00000105472 ENSG00000116962 ENSG00000136689 PMC4326213__F3 Immune-initiated, complement-mediated erythrocyte destruction in cold agglutinin disease (CAD) and cold agglutinin syndrome (CAS) ENSG00000166278 PMC10945329__F10 Exosomes generated from human adipose mesenchymal stem cells reduce hepatic fibrosis by suppressing the PI3K/Akt/mTOR signaling pathway and altering choline metabolism ENSG00000198793 ENSG00000111666 PMC7139953__F3 Mucins signaling in the benign and malignant pathologies of the colon ENSG00000281324 ENSG00000065361 ENSG00000291971 ENSG00000026508 ENSG00000168036 ENSG00000175104 ENSG00000168610 ENSG00000145113 ENSG00000173702 ENSG00000293532 ENSG00000178568 PMC8787114__F2 Mechanoregulation of Vascular Endothelial Growth Factor Receptor 2 in Angiogenesis ENSG00000107338 ENSG00000070831 ENSG00000291971 ENSG00000010810 ENSG00000163914 ENSG00000067900 PMC7049507__F4 Analysis of miRNA‐mRNA regulatory network concerning Phospholipase D signaling pathway ENSG00000049130 PMC7589708__F2 Wnt non-canonical signalling pathways ENSG00000169071 ENSG00000100592 ENSG00000163914 PMC12149821__F1 Representation of phosphoinositide 3-kinase/protein kinase B/mechanistic target of rapamycin sequential signaling pathway in breast cancer ENSG00000002330 ENSG00000150907 PMC3045367__F1 Exploring the Evolutionary Relationship of Insulin Receptor Substrate Family Using Computational Biology ENSG00000169047 ENSG00000133124 PMC6407099__F4 Role of Itch in Type I non-canonical Hh pathway ENSG00000078747 ENSG00000128602 PMC6407099__F3 Role of Itch in canonical Hh pathway ENSG00000106571 ENSG00000078747 ENSG00000166278 ENSG00000133961 ENSG00000128602 PMC2634101__F1 Model summarizing some of the pathways described in this review leading to chemotaxis and cell motility ENSG00000070831 ENSG00000145321 PMC5739549__F1 Mechanisms leading to transitory or sustained PD-1 expression in activated and exhausted T cells ENSG00000181847 ENSG00000134982 PMC3977192__F8 LTP pathway components and interacting proteins: response in hippocampus ENSG00000166869 ENSG00000142192 ENSG00000188386 ENSG00000157540 ENSG00000002330 ENSG00000187446 ENSG00000198793 ENSG00000168036 ENSG00000171791 ENSG00000159200 ENSG00000148660 ENSG00000010810 ENSG00000178568 PMC8085045__F7 Alantolactone inhibits cervical cancer progression by downregulating BMI1 ENSG00000168283 ENSG00000170558 ENSG00000168610 ENSG00000285379 PMC3260807__F4 Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health ENSG00000149311 ENSG00000157764 ENSG00000168036 ENSG00000079432 PMC3260807__F2 Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health ENSG00000169291 ENSG00000002330 ENSG00000291971 ENSG00000198793 ENSG00000146648 PMC3260807__F1 Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health ENSG00000198793 PMC6504273__F1 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway network for Kashin-Beck disease (KBD)-related genes ENSG00000125735 ENSG00000181104 ENSG00000124491 ENSG00000150093 ENSG00000091409 ENSG00000105499 ENSG00000115718 ENSG00000122194 ENSG00000185010 ENSG00000274619 ENSG00000101981 ENSG00000130164 ENSG00000109861 ENSG00000120868 ENSG00000171560 ENSG00000165471 ENSG00000009724 ENSG00000259207 ENSG00000113600 ENSG00000005961 ENSG00000000971 ENSG00000198626 ENSG00000088926 ENSG00000166278 ENSG00000162104 PMC2490815__F4 IL-12, IL-23 and IL-27 are heterodimeric cytokines signals through Jak-Stat pathway and induce Th1/Th17 differentiation and T-bet expression in T cells ENSG00000162594 ENSG00000138378 ENSG00000111537 ENSG00000105397 ENSG00000168610 PMC9237599__F7 Exosomes-mediated tumor treatment: One body plays multiple roles ENSG00000002330 PMC2490815__F3 Regulation of NFKB pathway by PPAR agonists in CNS diseases ENSG00000239732 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC3750075__F1 ACK1/TNK2, a non-receptor tyrosine kinase (NRTK), represents a paradigm of tyrosine kinase signaling that appears to be addictive in cancer cells ENSG00000138798 PMC5220089__F4 IPA-mapped CVD pathway for the 1890 compounds distributed in the top 10 herbs ENSG00000197372 ENSG00000112977 ENSG00000149930 ENSG00000291971 ENSG00000073756 ENSG00000171596 PMC3251006__F5 ECM-receptor interaction and focal adhesion pathway ENSG00000169291 PMC8931742__F1 Schematic depicting the ER stress response signaling pathway after SCI ENSG00000128272 ENSG00000100219 PMC8146469__F1 Unlocking the Non-IgE-Mediated Pseudo-Allergic Reaction Puzzle with Mas-Related G-Protein Coupled Receptor Member X2 (MRGPRX2) ENSG00000183695 ENSG00000137033 ENSG00000146469 PMC12111248__F9 Cdh23 regulating rod cell calcium ion transport (image created by Figdraw) ENSG00000112599 ENSG00000114349 ENSG00000163914 ENSG00000145321 ENSG00000107736 PMC10929194__F1 Canonical pathways downstream of KRAS mutations ENSG00000006451 ENSG00000144118 ENSG00000198793 ENSG00000177606 ENSG00000277276 PMC10929194__F3 Signaling pathways in the TME ENSG00000167601 ENSG00000163734 ENSG00000265972 PMC11353192__F7 Lactate and LOX regulation of the HCAR1-RAS/PI3K signaling cascades ENSG00000115904 PMC5084369__F5 PHBHHx synthesis pathway with R-specific enoyl-CoA hydratase ENSG00000039537 ENSG00000173611 ENSG00000166278 PMC9289230__F1 Neutrophils: New Critical Regulators of Glioma ENSG00000189403 ENSG00000108654 ENSG00000026103 PMC4823071__F7 In silico pathway analysis in cervical carcinoma reveals potential new targets for treatment ENSG00000149311 PMC3978517__F2 The replication checkpoint pathway activated following DNA damage ENSG00000188486 ENSG00000175054 ENSG00000164053 PMC3059437__F1 Shmt1 Heterozygosity Impairs Folate-Dependent Thymidylate Synthesis Capacity and Modifies Risk of Apcmin-Mediated Intestinal Cancer Risk ENSG00000284320 ENSG00000228716 PMC8361660__F6 Early evolutionary landscape of osteosarcoma provides clues for targeted treatment strategies ENSG00000012048 ENSG00000112576 ENSG00000135446 ENSG00000123374 ENSG00000139687 PMC8790521__F2 Metabolic Reprogramming in Gastric Cancer: Trojan Horse Effect ENSG00000163599 ENSG00000145321 ENSG00000049768 PMC9353726__F8 Network of deregulated genes that were differentially expressed upon c-MYC inhibition after lomitapide treatment as determined by Ingenuity Pathway Analysis. Color code: green, downregulation; red, upregulation ENSG00000282905 ENSG00000002330 ENSG00000100906 ENSG00000109320 ENSG00000089685 ENSG00000136997 ENSG00000217236 ENSG00000164938 ENSG00000258643 ENSG00000178685 ENSG00000010671 PMC2913512__F2 G Protein-Coupled Receptor 87: a Promising Opportunity for Cancer Drug Discovery ENSG00000163914 ENSG00000138271 PMC9637672__F12 Rapid genomic changes by mineralotropic hormones and kinase SIK inhibition drive coordinated renal Cyp27b1 and Cyp24a1 expression via CREB modules ENSG00000118972 ENSG00000152266 ENSG00000037897 ENSG00000019186 ENSG00000160741 PMC6433803__F2 Influence of non-oncogenic viruses on the components of non-canonical NFKB signaling ENSG00000104856 ENSG00000088888 ENSG00000131323 ENSG00000127191 PMC6667742__F7 A model demonstrating the multiple platelet activation pathways inhibited by the methylated metabolites of quercetin ENSG00000213658 ENSG00000197943 PMC6433803__F1 Non-canonical NFKB activation pathway ENSG00000104856 ENSG00000131323 ENSG00000127191 PMC8652378__F1 Oxalate synthesis pathway and molecular mechanisms leading to primary hyperoxaluria ENSG00000241935 PMC3684282__F10 Schematic of myelin-mediated activation of the TGFB signaling pathway and downregulation of Smad2 by SLPI ENSG00000124107 PMC7523359__F7 Roles and locations of CCND2 and CTNNB1 in Hippo signaling pathway and HPV infection pathway ENSG00000168036 ENSG00000118971 PMC4001324__F1 Simplified overview of the receptor tyrosine kinase (RTK)-RAS and RAS-related RHEB signaling pathways ENSG00000110395 ENSG00000198793 ENSG00000115904 ENSG00000108061 ENSG00000196712 PMC3502886__F1 PI3K/Akt/mTOR pathway regulates central carbon metabolism ENSG00000122966 ENSG00000198793 PMC7532541__F8 AFP promotes HCC progression by suppressing the HuR-mediated Fas/FADD apoptotic pathway ENSG00000168040 ENSG00000081051 ENSG00000064012 ENSG00000026103 PMC9145061__F1 Functional Properties of Cancer Epithelium and Stroma-Derived Exosomes in Head and Neck Squamous Cell Carcinoma ENSG00000091317 ENSG00000105401 ENSG00000146648 PMC4915121__F1 Conserved longevity-regulatory components of insulin/IGF-1 signaling pathway in C PMC6073358__F9 Signaling pathways were regulated by HSAF ENSG00000135446 ENSG00000105810 PMC2683723__F6 Insulin–EGF signal integration ENSG00000291971 ENSG00000087842 ENSG00000146648 PMC3939313__F1 Quantitative Lipid Metabolomic Changes in Alcoholic Micropigs with Fatty Liver Disease ENSG00000042832 ENSG00000173599 ENSG00000099194 ENSG00000133027 PMC3499189__F2 Synopsis of major pathways activating mTORC1 ENSG00000213658 ENSG00000169047 ENSG00000140443 PMC4077447__F2 6-Thioguanine: A Drug With Unrealized Potential for Cancer Therapy ENSG00000198931 ENSG00000099810 ENSG00000116984 PMC3499189__F3 Aberrations of PI3K-Akt-mTORC1 signaling pathway in prostate cancer ENSG00000213658 ENSG00000169047 ENSG00000140443 PMC9125579__F5 Contribution of Mitochondria to Insulin Secretion by Various Secretagogues ENSG00000151376 ENSG00000065833 ENSG00000122966 ENSG00000173599 ENSG00000086991 ENSG00000172005 ENSG00000169710 ENSG00000112992 ENSG00000062485 PMC11900999__F3 This figure shows the role of NETs in AS and its related mechanisms ENSG00000162711 ENSG00000003436 ENSG00000239732 ENSG00000110799 ENSG00000005381 PMC9125579__F4 Contribution of Mitochondria to Insulin Secretion by Various Secretagogues ENSG00000144935 ENSG00000156026 ENSG00000172005 PMC11900999__F2 This figure shows a schematic diagram of the molecular mechanism of neutrophil suicidal NETosis ENSG00000278718 ENSG00000135446 ENSG00000105810 ENSG00000005381 PMC4519337__F3 Transcriptome Profiling of Wild-Type and pga-Knockout Mutant Strains Reveal the Role of Exopolysaccharide in Aggregatibacter actinomycetemcomitans ENSG00000117400 ENSG00000198951 ENSG00000124357 PMC4589489__F3 Schematic of the ERBB(EGFR)/KRAS/BRAF/MAPK signaling axis, and its connection with the PI3 Kinase pathway ENSG00000140992 ENSG00000198793 ENSG00000146648 PMC9583506__F2 TRIM family contribute to tumorigenesis, cancer development, and drug resistance ENSG00000154370 ENSG00000108395 ENSG00000166326 ENSG00000106785 ENSG00000113595 ENSG00000134982 ENSG00000102871 ENSG00000119401 ENSG00000204977 ENSG00000198793 ENSG00000137699 ENSG00000168036 ENSG00000171206 ENSG00000121236 ENSG00000116525 ENSG00000278211 ENSG00000163462 ENSG00000183579 ENSG00000119283 ENSG00000183718 ENSG00000166436 ENSG00000162722 ENSG00000213186 ENSG00000132109 ENSG00000109654 ENSG00000168040 ENSG00000026508 ENSG00000132481 ENSG00000122779 ENSG00000291501 ENSG00000121060 ENSG00000221926 ENSG00000130726 PMC4034385__F1 Chromatin modifications as therapeutic targets in MLL-rearranged Leukemia ENSG00000141867 ENSG00000128886 ENSG00000104885 PMC4491517__F1 Schematic diagraming central role of pyruvate in glycolytic, citric acid cycle (CAC), and accessory pathways ENSG00000135218 ENSG00000147162 ENSG00000198793 ENSG00000173599 PMC10921743__F10 AMPK involvement in central sensitization of chronic migraine ENSG00000041982 ENSG00000118520 ENSG00000276043 PMC3912804__F1A Hedgehog signaling pathways in vertebrates-without hedgehog ligand ENSG00000128602 PMC8114223__F1 Implications of the germline variants of DNA damage response genes detected by cancer precision medicine for radiological risk communication and cancer therapy decisions ENSG00000188486 ENSG00000136492 ENSG00000083093 ENSG00000185379 ENSG00000187790 ENSG00000112039 ENSG00000158169 ENSG00000139618 ENSG00000149311 ENSG00000012048 ENSG00000144554 ENSG00000182185 ENSG00000108384 ENSG00000051180 PMC4496349__F6 MiR-193a-3p-regulated ING5 gene activates the DNA damage response pathway and inhibits multi-chemoresistance in bladder cancer ENSG00000168395 ENSG00000168214 ENSG00000109320 ENSG00000136997 ENSG00000169635 ENSG00000106459 PMC11125340__F7 Platelet-Derived Growth Factor Receptor Beta and JAK2/STAT3 Pathway ENSG00000102145 ENSG00000159216 ENSG00000134057 ENSG00000163914 ENSG00000123374 ENSG00000168610 PMC8395054__F3 CDK4, CDK6/cyclin-D1 Complex Inhibition and Radiotherapy for Cancer Control: A Role for Autophagy ENSG00000139687 PMC4836462__F5 Morphogens involved in BBB development and integrity influence signaling of common pathways ENSG00000157404 ENSG00000070831 ENSG00000198793 ENSG00000163914 ENSG00000187840 PMC7314312__F2 PI3K-AKT network at the interface of oncogenic signalling and cancer metabolism ENSG00000131473 ENSG00000265972 ENSG00000008130 ENSG00000084774 PMC7314312__F1 PI3K-AKT network at the interface of oncogenic signalling and cancer metabolism ENSG00000128272 ENSG00000136997 PMC8714965__F5 Compendium of Information on the Lysosome ENSG00000177169 ENSG00000177058 ENSG00000134108 PMC7314312__F4 PI3K-AKT network at the interface of oncogenic signalling and cancer metabolism ENSG00000065911 ENSG00000128272 ENSG00000084774 PMC7314312__F5 PI3K-AKT network at the interface of oncogenic signalling and cancer metabolism ENSG00000228716 ENSG00000131473 ENSG00000124479 ENSG00000169710 ENSG00000008130 PMC8874499__F3 Deciphering the Interactions of SARS-CoV-2 Proteins with Human Ion Channels Using Machine-Learning-Based Methods ENSG00000152661 ENSG00000104321 ENSG00000078668 ENSG00000149782 ENSG00000143839 ENSG00000123104 ENSG00000167371 ENSG00000169032 ENSG00000171388 ENSG00000137841 ENSG00000105642 ENSG00000179002 ENSG00000150782 ENSG00000186815 ENSG00000159248 ENSG00000080709 ENSG00000127588 ENSG00000143603 ENSG00000196689 PMC10376127__F2 New Insights on the Uptake and Trafficking of Coenzyme Q ENSG00000132423 ENSG00000115520 ENSG00000167113 ENSG00000123815 ENSG00000119723 ENSG00000110871 ENSG00000163050 ENSG00000088682 ENSG00000197429 ENSG00000267673 ENSG00000161513 ENSG00000148459 ENSG00000137714 ENSG00000173085 ENSG00000135469 ENSG00000167186 PMC10376127__F1 Coenzyme Q functions ENSG00000171503 ENSG00000181019 ENSG00000166278 ENSG00000100033 ENSG00000102967 ENSG00000016391 PMC11519791__F10 An illustration of the proposed role of cholinergic and calcium signaling pathways in ISIAF and WK treatment in neuronal and non-neuronal (cardiac) systems ENSG00000133019 ENSG00000087085 PMC4538308__F1 The mechanism by which DHA may interfere with the molecular signalling by activating glycolytic phenotype ENSG00000134086 PMC3912804__F2D Hedgehog signaling pathway in cancers -Type IIIb-Reverse Paracrine Ligand-dependent cancers ENSG00000128602 PMC3912804__F2C Hedgehog signaling pathway in cancers -Type III- Paracrine Ligand-dependent cancers ENSG00000128602 PMC4933505__F1 Emerging role of coagulation proteases in kidney disease ENSG00000180210 ENSG00000003436 ENSG00000134982 ENSG00000173599 PMC3912804__F2B Hedgehog signaling pathway in cancers -Type II- Autocrine Ligand-dependent cancers ENSG00000128602 PMC3912804__F2A Hedgehog signaling pathway in cancers-Type I-Ligand-independent cancers ENSG00000128602 PMC5796261__F1 TREM2-DAP12 signaling ENSG00000168036 ENSG00000126353 PMC7047281__F3 Interaction network of differentially expressed miRNAs (DERs) and genes ENSG00000103479 ENSG00000171105 ENSG00000124882 ENSG00000130522 ENSG00000135446 ENSG00000169047 ENSG00000177606 ENSG00000172543 ENSG00000118971 ENSG00000146648 ENSG00000163815 ENSG00000160691 PMC7862576__F7 Mdfi overexpression promoted C2C12 cell differentiation and positively modulated fast-to-slow-twitch muscle fibers transformation ENSG00000159173 ENSG00000117054 ENSG00000112559 ENSG00000161533 ENSG00000198125 ENSG00000198734 ENSG00000062485 ENSG00000186469 PMC9701405__F6 Modular networks and genomic variation during progression from stable angina pectoris through ischemic cardiomyopathy to chronic heart failure ENSG00000019991 ENSG00000087245 ENSG00000108691 ENSG00000169291 ENSG00000188822 ENSG00000149968 ENSG00000143839 ENSG00000091879 ENSG00000132693 ENSG00000127948 ENSG00000150630 PMC3962345__F4 Searching for Novel Cdk5 Substrates in Brain by Comparative Phosphoproteomics of Wild Type and Cdk5−/− Mice ENSG00000176884 ENSG00000070831 PMC8526972__F1 Inter-Kingdom Signaling of Stress Hormones: Sensing, Transport and Modulation of Bacterial Physiology ENSG00000123454 ENSG00000141744 PMC3005418__F8 Rapid activation of the bivalent gene Sox21 requires displacement of multiple layers of gene-silencing machinery ENSG00000198901 ENSG00000101751 ENSG00000196591 PMC2801289__F1 UDP-galactose synthesis in L PMC5580928__F1 Post-translational Modifications (PTMs) that Modulate the Retinoic Acid-Inducible Gene I (RIG-I)-like receptor (RLR)–Mitochondrial Antiviral Signaling Protein (MAVS) Signaling Pathway ENSG00000094631 ENSG00000135655 ENSG00000133874 ENSG00000176624 ENSG00000101782 ENSG00000146833 ENSG00000166278 ENSG00000101695 ENSG00000183735 ENSG00000088888 ENSG00000140455 ENSG00000083799 ENSG00000121060 ENSG00000143258 PMC3538326__F7 Proposed mechanisms of the reduced activation of G3139 in RIT-INPs ENSG00000239732 ENSG00000171791 PMC7435027__F4 Illustration of the effects of acetaminophen on glutathione, antioxidant processes, and metabolic processes ENSG00000065833 ENSG00000100714 ENSG00000082212 PMC6397284__F4 Promoter hypomethylation of genes involved in myogenesis, structural dynamics of muscles and CDC42 signaling ENSG00000070831 ENSG00000102302 PMC7443979__F6 The molecular mechanism of the ascorbic acid anticancer effect ENSG00000106327 ENSG00000117118 PMC4400383__F3 Insulin binding causes activation of the insulin receptor (IR), which phosphorylates different substrate adaptors such as the insulin receptor substrate (IRS) PMC3532605__F7 NFKB signalling pathway ENSG00000174123 ENSG00000104856 ENSG00000226275 ENSG00000291603 ENSG00000163235 ENSG00000138798 ENSG00000173039 ENSG00000197943 ENSG00000198125 ENSG00000150455 ENSG00000164342 PMC11624796__F7 Natural lung-tropic TH9 cells: a sharp weapon for established lung metastases ENSG00000107562 ENSG00000078747 ENSG00000175104 ENSG00000121966 PMC3758882__F1 Normal complement activation cascade and its regulation ENSG00000039537 ENSG00000113600 ENSG00000166278 ENSG00000236625 PMC6358298__F3 PTEN- and IPMK-mediated nuclear phosphoinositide signaling through SF-1 ENSG00000151151 PMC4871119__F1 (Adapted from Alinari, Quinion, and Blum ENSG00000177455 ENSG00000186716 ENSG00000010671 ENSG00000121966 PMC5374451__F3 Molecular signaling involved in nephrogenesis ENSG00000128713 ENSG00000162552 ENSG00000145147 ENSG00000168036 ENSG00000138759 ENSG00000103449 ENSG00000164056 ENSG00000107485 ENSG00000126778 ENSG00000185008 ENSG00000100625 ENSG00000075213 ENSG00000177045 PMC4545518__F6 Simplified schematic of the canonical Notch signaling pathway ENSG00000159921 ENSG00000168214 ENSG00000114315 PMC2884164__F5 Significant signaling pathway networks mined from pituitary adenoma comparative dataset ENSG00000133116 ENSG00000116990 PMC5300302__F7 The trans-sulphuration pathway coupled with glutathione synthesis ENSG00000151224 ENSG00000116761 PMC2915700__F6 Schematic representation of the line of events by which HA modulates the leukocyte-EC interaction ENSG00000170961 ENSG00000125538 ENSG00000026508 PMC9678227__F9 Xuanfei Baidu Decoction suppresses complement overactivation and ameliorates IgG immune complex-induced acute lung injury by inhibiting JAK2/STAT3/SOCS3 and NFKB signaling pathway ENSG00000125538 ENSG00000168610 PMC4638034__F3 Signaling pathways ENSG00000100714 ENSG00000173599 ENSG00000168610 ENSG00000146648 PMC3528620__F4 Chemokine Signaling Pathway from the KEGG database (ID: mmu04062) overlaid with log2 fold change values for genes differentially expressed between DBA/2 and C57BL/6 at day 14 ENSG00000067606 PMC6277787__F12 LPS signaling pathway in teleost macrophages ENSG00000167207 ENSG00000106100 PMC2884164__F9 ERK/MAPK signaling pathway that is involved with pituitary adenoma comparative-proteomic data ENSG00000172680 ENSG00000002330 ENSG00000107669 PMC3607163__F2 Role of the Wnt-Frizzled system in cardiac pathophysiology: a rapidly developing, poorly understood area with enormous potential ENSG00000100592 ENSG00000168036 PMC3607163__F1 Role of the Wnt-Frizzled system in cardiac pathophysiology: a rapidly developing, poorly understood area with enormous potential ENSG00000107404 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6542591__F1 Adaptive and pro-apoptotic pathways of the UPR ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC4554646__F2 Proposed biosynthetic pathway of the prodiginines and the related 4- m ethoxybipyrrole, YP1 ENSG00000065833 ENSG00000135845 ENSG00000124155 ENSG00000206177 ENSG00000133028 PMC2634657__F2 Leptin Neuroprotection in the Central Nervous System: Mechanisms and Therapeutic Potentials ENSG00000005882 ENSG00000150907 PMC8621753__F3 Melatonin and Pathological Cell Interactions: Mitochondrial Glucose Processing in Cancer Cells ENSG00000096717 ENSG00000142082 PMC12067801__F4 ANO1 participates in various signaling pathways ENSG00000198793 ENSG00000146648 PMC8664842__F8 Working model of KDM6B inhibition in neuroblastoma ENSG00000135446 ENSG00000105810 ENSG00000132510 ENSG00000102974 PMC6857641__F1 The tryptophan catabolism pathway ENSG00000262635 PMC5836032__F3 Outline of melatonin biosynthesis in the fish pineal gland ENSG00000065833 ENSG00000105251 PMC5481368__F1 Scheme tentatively summarizing the involvement of ACBD7 and its related product NDN in the effects of leptin in the ARC ENSG00000115138 ENSG00000166603 ENSG00000176244 PMC8987581__F8 Anti-Inflammatory Effects of Ginsenoside Rb3 in LPS-Induced Macrophages Through Direct Inhibition of TLR4 Signaling Pathway ENSG00000125538 ENSG00000136869 PMC4975561__F1 Roles of the PtdIns(3,4,5)P3/Akt pathway on insulin signaling in liver fat and muscle tissue with representative substrates indicated ENSG00000186480 PMC2811067__F2 Some of the stress response transcription factor pathways with homologs in N ENSG00000178573 ENSG00000106546 ENSG00000079999 PMC6385390__F4 Networks representing protein-protein interactions in differentially regulated proteins from the NOD1 (HS578T/NOD1) (a) and NOD2 (HS578T/NOD2) (b) experimental groups ENSG00000166340 ENSG00000184254 ENSG00000167207 ENSG00000137815 ENSG00000147604 ENSG00000188846 ENSG00000182985 ENSG00000163820 ENSG00000063177 ENSG00000154553 ENSG00000171241 ENSG00000132382 ENSG00000165502 ENSG00000171490 ENSG00000128228 ENSG00000144713 ENSG00000166974 ENSG00000214753 ENSG00000155438 ENSG00000106100 ENSG00000174444 ENSG00000101310 ENSG00000142541 ENSG00000174748 ENSG00000113460 ENSG00000173757 ENSG00000138303 ENSG00000171848 PMC2269037__F3 PI3K/AKT signaling pathway activated by 3Alpha-diol ENSG00000002330 PMC6895449__F7 Illustration of the NEK2/Beta-catenin/Myc/KDM5B/H3K4me3 pathway ENSG00000151376 ENSG00000117650 ENSG00000117139 ENSG00000168036 PMC6415318__F7 Schematic diagram of molecular mechanisms of Shuangyu Tiaozhi Granule (STG) attenuates hypercholesterolemia in rat fed HC diet ENSG00000138075 ENSG00000130164 ENSG00000167910 ENSG00000113161 ENSG00000120437 ENSG00000143921 PMC9204297__F3 NLRP3-Dependent Pyroptosis: A Candidate Therapeutic Target for Depression ENSG00000278718 ENSG00000162711 ENSG00000135218 ENSG00000136869 ENSG00000062485 PMC9204297__F2 NLRP3-Dependent Pyroptosis: A Candidate Therapeutic Target for Depression ENSG00000278718 ENSG00000162711 ENSG00000130164 ENSG00000163568 ENSG00000091592 PMC3059896__F2 Genetics and molecular pathology of Stargardt-like macular degeneration ENSG00000173976 ENSG00000158169 PMC4001025__F1 Vpr induces G2/M arrest through activation of the SLX4 complex ENSG00000175054 ENSG00000154920 ENSG00000134057 ENSG00000188827 ENSG00000166851 PMC387762__F5 CREB pathway and possible positions of proteins whose genes contain CREB1 binding sites ENSG00000099991 PMC8678610__F5 Lactic Acid Transport Mediated by Aquaporin-9: Implications on the Pathophysiology of Preeclampsia ENSG00000143158 ENSG00000103569 ENSG00000060762 PMC9253674__F7 Protective Effect of Danshen Zexie Decoction Against Non-Alcoholic Fatty Liver Disease Through Inhibition of ROS/NLRP3/IL-1B Pathway by Nrf2 Signaling Activation ENSG00000278718 ENSG00000162711 ENSG00000178573 ENSG00000125538 ENSG00000023909 ENSG00000079999 PMC9256000__F3 Response biomarkers of inhalation exposure to cigarette smoke in the mouse lung ENSG00000186074 ENSG00000189377 ENSG00000102962 ENSG00000135077 ENSG00000115008 ENSG00000111537 ENSG00000161921 ENSG00000138755 ENSG00000136689 PMC5912671__F2 Fanconi Anemia ENSG00000149311 ENSG00000175054 ENSG00000111537 ENSG00000115415 PMC5912671__F1 Fanconi Anemia ENSG00000012048 ENSG00000197299 ENSG00000051180 PMC4464398__F5 MAPK signaling pathway and neurotrophin signaling pathway maps ENSG00000087095 ENSG00000172680 ENSG00000169291 ENSG00000101146 ENSG00000002330 ENSG00000157764 ENSG00000170458 ENSG00000177606 ENSG00000130159 ENSG00000101224 ENSG00000026103 PMC8666374__F1 Schematic diagram showing common components and pathways driving cirrhosis-associated immune dysfunction and novel coronavirus-related disease ENSG00000111537 ENSG00000170458 PMC8839250__F10 Biological Properties of Vitamins of the B-Complex, Part 1: Vitamins B1, B2, B3, and B5 ENSG00000105835 ENSG00000123572 ENSG00000278488 PMC8091792__F1 Pyroptosis: a new paradigm of cell death for fighting against cancer ENSG00000162711 ENSG00000150782 ENSG00000002330 ENSG00000163568 ENSG00000125538 ENSG00000091592 ENSG00000145649 ENSG00000189403 ENSG00000091106 PMC4595979__F1 LOX pathway ENSG00000062485 PMC3672007__F2 Ingenuity pathways analysis canonical pathway IGF1 signaling This figure shows the IGF1 signaling pathway, with significantly upregulated genes in red, downregulated genes in green, and genes that did not meet our criteria for significance in gray ENSG00000099330 ENSG00000002330 ENSG00000106070 ENSG00000177606 ENSG00000168610 ENSG00000140443 PMC11911380__F2 Inflammatory crosstalk and anti-inflammatory mechanisms in the angiotensin II-induced fibrosis pathway ENSG00000111837 PMC9480600__F5 Exosomes in Pharyngucutaneous Fistula After Total Laryngectomy ENSG00000162711 ENSG00000156709 ENSG00000198793 ENSG00000142082 ENSG00000247077 ENSG00000079999 PMC8891295__F1 Opposing transcriptional programs ensure cholesterol homeostasis in macrophages ENSG00000130164 ENSG00000160179 PMC4133945__F1 Dickkopf-1 is a key regulator of myeloma bone disease: opportunities and challenges for therapeutic intervention ENSG00000134982 ENSG00000168036 PMC8471303__F1 Age-Dependent Decrease in Hepatic Geranylgeranoic Acid Content in C3H/HeN Mice and Its Oral Supplementation Prevents Spontaneous Hepatoma ENSG00000197429 ENSG00000100083 PMC5731927__F6 Genipin suppresses colorectal cancer cells by inhibiting the Sonic Hedgehog pathway ENSG00000171791 PMC5962057__F1 Monoclonal antibody targeting amyloid B (AB) restores complement factor I bioactivity: Potential implications in age-related macular degeneration and Alzheimer’s disease ENSG00000039537 ENSG00000197713 ENSG00000113600 ENSG00000125538 PMC5414755__F1 Signaling pathway regulating the initiation of autophagy and the formation of autophagosomes ENSG00000110497 ENSG00000123395 ENSG00000145782 PMC12112713__F2 Notch signaling pathway ENSG00000140564 ENSG00000128917 ENSG00000158828 ENSG00000184916 ENSG00000090932 PMC7975703__F7 Proposed Schematic for AKR1B10 activating TLR4/NFKB signaling pathway by promoting FFA synthesis in NPC ENSG00000198074 ENSG00000172936 ENSG00000136869 PMC1988867__F7 Ingenuity pathway analysis showing regulatory relationships among differentially expressed transcripts ENSG00000211445 ENSG00000125148 ENSG00000100906 ENSG00000118785 ENSG00000197632 ENSG00000147133 ENSG00000203857 ENSG00000115461 ENSG00000104368 ENSG00000137801 PMC10942021__F9 Crosstalk between mTOR and AMPK ENSG00000145604 ENSG00000102871 ENSG00000123374 ENSG00000100554 PMC7239059__F5 SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing ENSG00000119397 ENSG00000184012 PMC6864306__F5 Relevant signaling pathways deregulated in glioblastoma: receptor tyrosine kinase/PI3K/PTEN/AKT/mTOR pathway is shown in blue, CDKN2A/CDK4/6/ retinoblastoma is shown in green and p53/MDM2/p14ARF signaling pathway is shown in red ENSG00000124102 ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000146648 PMC5742740__F1 Hippo signalling pathway in Drosophila and mammals ENSG00000150457 ENSG00000131023 PMC4623399__F6 Summary of protein and metabolites data at t = 8 h ENSG00000166278 ENSG00000146701 PMC6251731__F6 Involvement of Akt in Mitomycin C and Its Analog Triggered Cytotoxicity in MCF-7 and K562 cancer cells ENSG00000143878 ENSG00000105401 ENSG00000198793 ENSG00000130513 PMC7335506__F2 Therapeutic targets on the interleukin‐1 pathway ENSG00000115590 ENSG00000125538 ENSG00000172936 ENSG00000175104 ENSG00000115594 PMC8375987__F3 Three visualizations of part of the “PKC-gamma calcium signaling pathway in ataxia” at WikiPathways (wikipathways:WP4760) ENSG00000157087 ENSG00000138741 PMC8202022__F5 Host-Parasite Interaction of Atlantic salmon (Salmo salar) and the Ectoparasite Neoparamoeba perurans in Amoebic Gill Disease ENSG00000150782 ENSG00000169896 ENSG00000181847 ENSG00000125538 ENSG00000173039 ENSG00000168036 ENSG00000027697 ENSG00000136869 ENSG00000243646 ENSG00000164305 ENSG00000293532 ENSG00000007171 PMC4011807__F1 Pathophysiology of anthrax illustrated as a series of steps ENSG00000140564 ENSG00000281324 PMC2839261__F1 Effector pathways stimulated by Beta-ARs ENSG00000147488 ENSG00000166484 ENSG00000069956 ENSG00000146648 PMC3443208__F4 Prenatal Exposure to TCDD Triggers Significant Modulation of microRNA Expression Profile in the Thymus That Affects Consequent Gene Expression ENSG00000007944 ENSG00000110711 ENSG00000142627 ENSG00000185215 ENSG00000119888 ENSG00000159322 ENSG00000196468 ENSG00000150457 ENSG00000166484 ENSG00000187266 ENSG00000109586 ENSG00000047056 ENSG00000095739 ENSG00000152669 ENSG00000274334 ENSG00000291814 ENSG00000076321 ENSG00000166971 ENSG00000204217 ENSG00000127948 ENSG00000186832 ENSG00000163884 PMC9495176__F6 Bioinformatics and Genomic Analyses of the Suitability of Eight Riboswitches for Antibacterial Drug Targets ENSG00000284320 ENSG00000291958 ENSG00000092621 ENSG00000178445 PMC11529186__F6 Peripheral nerve injury exacerbated progression of muscle HO, caused by the release of NRG3, which induced osteogenic differentiation of FAPs via the ErbB4/PI3K/Akt signaling pathway ENSG00000178568 PMC7661519__F4 Gene pathway analysis of the co-expression and co-localization of mRNAs in this study ENSG00000182809 ENSG00000135931 ENSG00000198793 ENSG00000172159 ENSG00000151692 ENSG00000130304 ENSG00000134321 ENSG00000197530 ENSG00000134013 ENSG00000134326 ENSG00000137965 ENSG00000189403 ENSG00000196712 ENSG00000141971 PMC9207209__F3 Yeast as a Model to Unravel New BRCA2 Functions in Cell Metabolism ENSG00000074800 ENSG00000173805 ENSG00000100412 ENSG00000179091 ENSG00000178741 ENSG00000169299 PMC3713775__F2 MicroRNA and Signal Transduction Pathways in Tumor Radiation Response ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000051180 ENSG00000139618 PMC3713775__F1 MicroRNA and Signal Transduction Pathways in Tumor Radiation Response ENSG00000149311 ENSG00000178691 PMC8508046__F3 Targeted Sequencing Revealed Distinct Mutational Profiles of Ocular and Extraocular Sebaceous Carcinomas ENSG00000118058 ENSG00000005339 ENSG00000157764 ENSG00000105647 ENSG00000121879 ENSG00000149311 ENSG00000283780 ENSG00000113558 ENSG00000139613 ENSG00000108375 ENSG00000095002 ENSG00000139687 ENSG00000196712 ENSG00000127616 ENSG00000198625 ENSG00000109670 PMC11823264__F4 JNK signaling pathway ENSG00000070831 ENSG00000102871 ENSG00000100985 PMC6864436__F7 The schematic diagram of ICA activation of BMP2–induced osteoblast differentiation in C2C12 cells ENSG00000170365 ENSG00000120693 PMC10879531__F6 Mechanism of action of Gal-3 in the A-ED through the TLR4/MyD88/NFKB pathway ENSG00000172936 ENSG00000136869 PMC4818970__F3 Growth factor signaling pathway ENSG00000136997 PMC8874510__F1 Structural View of miRNA Biogenesis and Function ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC7272522__F2 Antioxidant and detoxifying processes involved in genoprotective activities ENSG00000106546 ENSG00000079999 PMC5870609__F5 Differential network of cancer pathway between BRCA tumor samples and controls ENSG00000183978 ENSG00000132906 ENSG00000104365 ENSG00000107562 ENSG00000138798 ENSG00000109906 ENSG00000196591 ENSG00000176533 ENSG00000175029 ENSG00000121879 ENSG00000197461 ENSG00000245848 ENSG00000066468 ENSG00000053747 ENSG00000117020 ENSG00000136160 ENSG00000151617 ENSG00000095002 ENSG00000186469 PMC4026869__F6 Gene network of 32 genes with pathway level expression change and mutation via GeneMANIA ENSG00000104365 ENSG00000157764 ENSG00000065618 ENSG00000065559 ENSG00000090776 ENSG00000092820 ENSG00000137801 ENSG00000145604 ENSG00000172167 ENSG00000157500 ENSG00000117020 ENSG00000177189 ENSG00000113790 ENSG00000146648 PMC2831005__F10 Yeast cell cycle ENSG00000261832 ENSG00000134982 ENSG00000197601 ENSG00000117399 PMC3940872__F7 Synthetic Alpha-Bromo-2′,3,4,4′-Tetramethoxychalcone (Alpha-Br-TMC) Inhibits the JAK/STAT Signaling Pathway ENSG00000099985 PMC6129988__F1 Current pathogenic model of psoriasis ENSG00000169248 ENSG00000169245 ENSG00000148346 ENSG00000115415 ENSG00000163739 ENSG00000138755 ENSG00000112149 ENSG00000168610 ENSG00000115009 ENSG00000112486 ENSG00000142224 PMC3199787__F4 Graphical representation of the IL-6 signaling pathway reveals significant gene expression changes following sarin-induced seizure ENSG00000177606 ENSG00000175899 ENSG00000132478 ENSG00000127191 PMC3923671__F1 Impairment of T Cell Function in Parasitic Infections ENSG00000026103 PMC8097256__F1 Human cell receptors: potential drug targets to combat COVID-19 ENSG00000178860 ENSG00000140564 ENSG00000197635 ENSG00000130234 ENSG00000182240 ENSG00000184012 PMC2626169__F1 A simplified view of the sex-determination pathway in XX animals (A) and XO animals (B) ENSG00000115884 ENSG00000162512 ENSG00000169439 ENSG00000115317 PMC7319585__F2 Molecular steps of FEME carrier formation ENSG00000124102 ENSG00000070831 ENSG00000079482 PMC4314372__F1 Biology of Castrate Resistant Prostate Cancer ENSG00000157554 ENSG00000125398 ENSG00000291971 ENSG00000198793 ENSG00000136997 ENSG00000124766 ENSG00000168036 PMC4785274__F1 H2S biosynthesis, functions, and metabolism PMC6085621__F7 Gold nanoparticles and Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC2837947__F2 Disruption of metabolic pathways involved in fat pad mass trait in mouse models of the candidate genes ENSG00000211445 ENSG00000103642 ENSG00000065833 ENSG00000042832 ENSG00000007237 ENSG00000184939 PMC9170767__F1 FunHoP: Enhanced Visualization and Analysis of Functionally Homologous Proteins in Complex Metabolic Networks ENSG00000156017 ENSG00000184254 ENSG00000117215 ENSG00000150656 ENSG00000140287 ENSG00000084110 ENSG00000105499 ENSG00000127472 ENSG00000241878 ENSG00000138308 ENSG00000133313 ENSG00000188089 ENSG00000158786 ENSG00000032444 ENSG00000243708 ENSG00000276870 ENSG00000125772 ENSG00000111684 ENSG00000160282 ENSG00000134255 ENSG00000159650 ENSG00000133027 PMC7471649__F6 Protein-protein interaction analysis by STRING ENSG00000105329 PMC9170767__F3 FunHoP: Enhanced Visualization and Analysis of Functionally Homologous Proteins in Complex Metabolic Networks ENSG00000174197 PMC11045904__F3 Intricate relationship between the gut and brain axes in PD is delineated by the schematic signaling pathway, with a focus on the inflammatory cascade triggered by dysbiosis at the gut lumen and BBB ENSG00000136869 PMC2846056__F3 Making the blastocyst: lessons from the mouse ENSG00000165556 ENSG00000197905 ENSG00000150457 ENSG00000131023 PMC11045904__F2 Inflammatory signaling pathway involved in AD is depicted in the figure ENSG00000162711 ENSG00000142192 ENSG00000125538 PMC9277163__F11 Protective Effects of Cinnamaldehyde on the Oxidative Stress, Inflammatory Response, and Apoptosis in the Hepatocytes of Salmonella Gallinarum-Challenged Young Chicks ENSG00000198793 PMC4947689__F1 Hcy metabolism PMC6678355__F5 Unigenes involved in the Wnt signaling pathway: Red and green represent upregulated and downregulated genes, respectively ENSG00000087095 ENSG00000100592 ENSG00000095739 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000196470 ENSG00000127948 PMC3051184__F9 Proposed model explaining upregulation of CREB expression by RA in NHTBE cells ENSG00000185591 ENSG00000167182 PMC6414239__F1 Metabolic perturbations in classic galactosemia beyond the Leloir pathway: insights from an untargeted metabolomic study PMC8027222__F6 Mating type specific transcriptomic response to sex inducing pheromone in the pennate diatom Seminavis robusta ENSG00000149311 ENSG00000099330 ENSG00000145321 ENSG00000051180 ENSG00000284844 ENSG00000117399 PMC5222372__F1 Overproduction of Alpha-Lipoic Acid by Gene Manipulated Escherichia coli ENSG00000189058 ENSG00000107798 PMC4659438__F4 Molecular pathogenesis and potential treatments for thrombotic microangiopathy in the glomerular endothelium ENSG00000110799 ENSG00000134982 ENSG00000162692 PMC6054450__F3 Merkel cell carcinoma ENSG00000118058 ENSG00000171444 ENSG00000148400 ENSG00000198793 ENSG00000049618 ENSG00000139618 ENSG00000117713 ENSG00000149311 ENSG00000012048 ENSG00000171456 ENSG00000183337 ENSG00000055609 ENSG00000095002 ENSG00000139687 ENSG00000127616 PMC7758635__F7 Hedgehog co-receptor BOC differentially regulates SHH signaling during craniofacial development ENSG00000144857 ENSG00000128602 PMC7746424__F2 Immunomodulation and cell apoptosis induced by the dopamine pathway ENSG00000184845 ENSG00000168610 ENSG00000149295 PMC3109102__F1 Basic intracellular molecular pathways regulating MN survival during development ENSG00000132906 ENSG00000198793 ENSG00000120868 ENSG00000064012 ENSG00000164305 PMC6306858__F1 Primer of the inflammatory cascade ENSG00000125538 ENSG00000172936 ENSG00000026103 PMC5595802__F1 Melanoma (Skin) tumorigenesis pathway, collected from KEGG ENSG00000002330 ENSG00000157764 ENSG00000135446 PMC5524810__F1 Angiotensin II signaling pathway underlying vascular aging ENSG00000087245 ENSG00000100985 PMC8962104__F2 Cellular stress signaling and the unfolded protein response in retinal degeneration: mechanisms and therapeutic implications ENSG00000123240 ENSG00000128272 ENSG00000067900 ENSG00000100219 ENSG00000143183 PMC4349622__F3 Schematic diagram showing the multi-regulation loops of LRRC4/NGL-2, miRNAs, TFs and target genes in glioma ENSG00000128594 ENSG00000136997 ENSG00000185591 ENSG00000166164 PMC4349622__F2 Schematic diagram showing the signaling regulation network of LRRC4/NGL-2 in glioma ENSG00000135446 ENSG00000123374 ENSG00000168610 ENSG00000121966 PMC5610024__F4 The dual role and therapeutic potential of high-mobility group box 1 in cancer ENSG00000189403 ENSG00000136869 PMC1304643__F2 Probability flux distributions for human red blood cell ENSG00000151657 ENSG00000196839 PMC7815415__F5 PPAR signaling pathway of potential targets of allicin ENSG00000150991 ENSG00000100979 PMC11611192__F8 The signaling pathway by which high glucose participates in the GEnCs injury via the RXRA/circ8411/miR-23a-5p/ABCA1 pathway ENSG00000278718 PMC3960371__F4 Autophagy Paradox and Ceramide ENSG00000223802 ENSG00000198793 PMC5658785__F4 Roles of microglia/macrophages in tumor progression of brain cancer and metastatic disease ENSG00000087245 ENSG00000125538 PMC8159759__F1 Bacterial Postbiotics as Promising Tools to Mitigate Cardiometabolic Diseases ENSG00000162711 ENSG00000135218 ENSG00000167207 ENSG00000136869 ENSG00000106100 ENSG00000213523 PMC5343846__F2 Effects of the loss of cell division cycle 73 (CDC73)/parafibromin on epigenetic regulatory mechanisms in PCas ENSG00000134371 ENSG00000155827 ENSG00000168036 PMC5343846__F1 Wnt/Beta-catenin pathway is potentially deregulated in PCas ENSG00000134371 ENSG00000281324 ENSG00000134982 ENSG00000168036 ENSG00000168646 PMC5975105__F1 Posttranscriptional regulation of lipid metabolism by non-coding RNAs and RNA binding proteins ENSG00000130164 ENSG00000119655 ENSG00000113161 ENSG00000141458 ENSG00000160179 ENSG00000079156 PMC8350729__F2 Anticancer Mechanisms of Salinomycin in Breast Cancer and Its Clinical Applications ENSG00000143799 ENSG00000198793 ENSG00000177606 ENSG00000171791 ENSG00000128602 ENSG00000168610 PMC9364366__F1 Key role of sphingolipid metabolism in cancer: New therapeutic targets, diagnostic and prognostic values, and anti-tumor immunotherapy resistance ENSG00000100422 ENSG00000102172 PMC6428898__F3 Mec1/Rad53 pathway senses ongoing DNA replication to inhibit mitotic entry ENSG00000260314 ENSG00000167941 ENSG00000141744 ENSG00000084072 ENSG00000118898 PMC8669377__F2 Targeting the “sweet spot” in septic shock – A perspective on the endothelial glycocalyx regulating proteins Heparanase-1 and -2 ENSG00000003436 ENSG00000170458 PMC7181071__F1 Main pathway for autophagy modulation ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000198382 ENSG00000144848 ENSG00000112561 ENSG00000145782 ENSG00000057663 PMC7935919__F3 Schematic illustration showing altered coagulation pathway proteins in polycystic ovary syndrome (PCOS) ENSG00000160752 ENSG00000003436 ENSG00000110799 ENSG00000122194 PMC9146244__F2 Neurotrophin Signaling Impairment by Viral Infections in the Central Nervous System ENSG00000168036 PMC7903350__F6 Compound-target network of EIF ENSG00000291971 ENSG00000138798 ENSG00000169047 ENSG00000198793 ENSG00000115904 ENSG00000169032 ENSG00000112715 ENSG00000121879 ENSG00000196396 ENSG00000124762 ENSG00000084676 ENSG00000128052 ENSG00000140443 ENSG00000171105 ENSG00000147437 ENSG00000005339 ENSG00000127955 ENSG00000170498 ENSG00000075073 ENSG00000140465 ENSG00000087460 ENSG00000169836 ENSG00000149311 ENSG00000291972 ENSG00000120899 ENSG00000166863 ENSG00000146648 ENSG00000113494 ENSG00000186469 ENSG00000141456 PMC7903350__F5 Pathways related to hypothalamic-pituitary-gonads axis and targets of EIF ENSG00000087245 ENSG00000171105 ENSG00000130164 ENSG00000070831 ENSG00000130385 ENSG00000113070 ENSG00000111837 PMC7412063__F4 Interactions between network molecules and DNA damage checkpoint pathways ENSG00000149311 ENSG00000008438 ENSG00000184232 ENSG00000157766 ENSG00000188784 ENSG00000166851 PMC5940270__F2 CGAS–cGAMP–STING pathway detects cytoplasmic DNA after DNA damage and activate type I IFNs and other cytokines ENSG00000183735 ENSG00000164430 PMC6096065__F7 Protein-protein interaction network of predicted target genes of hsa-miR-203 ENSG00000226492 ENSG00000196839 ENSG00000113140 PMC6096065__F6 Protein-protein interaction network of predicted target genes of hsa-miR-1 ENSG00000198521 ENSG00000121207 ENSG00000126016 ENSG00000105708 ENSG00000186532 ENSG00000291674 ENSG00000214513 ENSG00000138443 ENSG00000108960 ENSG00000241644 ENSG00000130224 ENSG00000111962 ENSG00000281766 ENSG00000154065 ENSG00000152214 ENSG00000154059 ENSG00000162105 ENSG00000100294 PMC4963809__F2 Schematic illustration of the canonical Wnt signal transduction cascade ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8227153__F4 Rintatolimod Induces Antiviral Activities in Human Pancreatic Cancer Cells: Opening for an Anti-COVID-19 Opportunity in Cancer Patients? ENSG00000187608 ENSG00000185745 ENSG00000172936 ENSG00000111331 ENSG00000135828 ENSG00000125347 ENSG00000127666 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC3236209__F6 Transcriptome Analysis of H2O2-Treated Wheat Seedlings Reveals a H2O2-Responsive Fatty Acid Desaturase Gene Participating in Powdery Mildew Resistance ENSG00000105722 PMC5794417__F8 Schematic diagram on regulation of PCSK9 on apoB via modulating the autophagy pathway affecting atherogenesis ENSG00000177169 ENSG00000126775 ENSG00000198793 ENSG00000057663 ENSG00000169174 PMC7255975__F2 Hypothetical mechanism by SARS-CoV-2 in establishing an inflammatory feedback loop between IL-6 and angiotensin II ENSG00000130234 PMC8888908__F1 Autophagy in the Neuronal Ceroid Lipofuscinoses (Batten Disease) ENSG00000177169 ENSG00000152348 ENSG00000198382 ENSG00000126775 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC5731853__F7 Let-7g suppresses both canonical and non-canonical NFKB pathways in macrophages leading to anti-atherosclerosis ENSG00000104856 ENSG00000173039 ENSG00000198911 PMC3465517__F5 Network analysis of proteins found to be significantly altered in abundance in the CSF proteome by ANOVA (p value <0.05) following analysis of individual subject samples ENSG00000142798 ENSG00000228278 ENSG00000105290 ENSG00000196743 ENSG00000120885 ENSG00000229314 ENSG00000184500 ENSG00000196136 ENSG00000274619 ENSG00000162729 ENSG00000018236 ENSG00000167779 ENSG00000171951 ENSG00000089199 ENSG00000154096 ENSG00000142192 ENSG00000000971 ENSG00000281931 ENSG00000138207 ENSG00000113905 ENSG00000118785 ENSG00000132692 ENSG00000288512 ENSG00000175899 ENSG00000026508 ENSG00000184371 ENSG00000276838 PMC9367204__F1 Of targeting host cell calcium dynamics to curtail SARS-CoV-2 infection and COVID-19 pathogenesis ENSG00000124102 ENSG00000167323 ENSG00000130234 ENSG00000293604 ENSG00000115020 ENSG00000184012 PMC5890336__F1 Canonical PI3K/AKT/mTOR signaling pathway ENSG00000065361 ENSG00000169047 ENSG00000155792 PMC3077214__F1 Signaling pathway components used to test gene–compound interactions ENSG00000138798 ENSG00000177606 ENSG00000128602 ENSG00000116096 PMC5582926__F9 Schematic description of EET-mediated perturbations in the Wnt1-NOV-PGC-1Alpha-HO-1 pathway in cardiac and adipose tissue of db/db mice ENSG00000125538 ENSG00000168036 ENSG00000125084 PMC7302136__F9 LncRNA LINC00314/miR-129-5p/GRM5 in osteogenic differentiation of ADSCs ENSG00000168036 PMC8210162__F11 Novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells ENSG00000188529 ENSG00000130726 ENSG00000198625 PMC10758056__F8 NRF2 promotes radiation resistance by cooperating with TOPBP1 to activate the ATR-CHK1 signaling pathway ENSG00000175054 ENSG00000164053 PMC10742465__F7 The proposed cardioprotective mechanism of hydrogen after CIH exposure ENSG00000182511 ENSG00000118564 ENSG00000079999 PMC2881280__F1 Schematic representation of the proposed enzymatic steps in the FAC -elicited JA biosynthesis pathway regulated by SIPK, WIPK and NPR1 PMC4586799__F4A The Potential Role of Hedgehog Signaling in the Luminal/Basal Phenotype of Breast Epithelia and in Breast Cancer Invasion and Metastasis ENSG00000074800 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC3975884__F1 EGFR associated signaling pathways in lung cancer ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC9603893__F3 Integrin Alpha v Beta 6 (AvB6) and Its Implications in Cancer Treatment PMC84608__F12 The central role of the E2F transcription factors in cell proliferation and apoptosis ENSG00000094804 PMC5998975__F8 Proposed crosstalk pathway between A2AR signaling and Semas ENSG00000187764 ENSG00000075213 PMC11123779__F5 Protein–protein gene network in RA-infected ducks ENSG00000213928 ENSG00000110330 ENSG00000135218 ENSG00000163629 ENSG00000114737 ENSG00000124875 ENSG00000162772 ENSG00000123496 ENSG00000089692 ENSG00000144802 ENSG00000134321 ENSG00000172216 ENSG00000082175 ENSG00000196549 ENSG00000036473 ENSG00000166228 ENSG00000095794 ENSG00000087245 ENSG00000142192 ENSG00000159128 ENSG00000138640 ENSG00000197217 ENSG00000100906 ENSG00000109743 ENSG00000050628 ENSG00000196358 ENSG00000164761 ENSG00000163874 ENSG00000116701 ENSG00000166670 ENSG00000276561 ENSG00000277943 ENSG00000007171 ENSG00000184979 ENSG00000117245 ENSG00000108691 ENSG00000129048 ENSG00000102970 ENSG00000134070 ENSG00000141655 PMC7204509__F4 EP remodels purine and arginine metabolism, glutathione homeostasis, and the Krebs cycle in BMDMs ENSG00000122966 ENSG00000172005 PMC6676405__F2 Putative Cripto-1 targets the MAPK, FA and ErbB signalling pathways ENSG00000291971 ENSG00000171791 ENSG00000077782 ENSG00000089159 PMC9241025__F3 Gene Regulatory Circuits in Innate and Adaptive Immune Cells ENSG00000138378 ENSG00000168214 ENSG00000137033 ENSG00000161405 ENSG00000107485 ENSG00000168610 PMC10342783__F9 Phenylalanine metabolism (a) and neuroactive ligand-receptor interaction (b) KEGG pathway ENSG00000122420 ENSG00000171388 ENSG00000161610 ENSG00000170893 ENSG00000198670 ENSG00000121853 ENSG00000152266 ENSG00000112964 ENSG00000174417 ENSG00000146469 ENSG00000102539 ENSG00000181408 ENSG00000157017 ENSG00000075073 ENSG00000157005 ENSG00000285456 ENSG00000010310 ENSG00000274473 ENSG00000169836 ENSG00000183395 ENSG00000109163 ENSG00000139574 ENSG00000096395 ENSG00000069482 ENSG00000291972 ENSG00000004948 ENSG00000166863 ENSG00000165409 ENSG00000113494 PMC6566886__F4 Adiponectin-induced signaling pathway ENSG00000157500 ENSG00000169047 ENSG00000198793 ENSG00000159346 ENSG00000285070 ENSG00000168610 PMC6566886__F3 Leptin-induced signaling pathway ENSG00000110711 ENSG00000169047 ENSG00000157036 ENSG00000168610 PMC9180116__F4 O-GlcNAcylation: The Underestimated Emerging Regulators of Skeletal Muscle Physiology ENSG00000159921 ENSG00000197713 ENSG00000147162 ENSG00000198408 ENSG00000169047 ENSG00000197487 ENSG00000124357 ENSG00000062485 PMC10603888__F10 Signal path analysis: (A) thyroid hormone synthesis (Calcium ions within the cell are transported outside the cell via the transmembrane, as indicated by the red boxes ENSG00000042832 ENSG00000140279 ENSG00000165409 ENSG00000116830 PMC7707960__F2 Putative schematic of the Rac1 signaling pathways involved in different neurodevelopmental disorders ENSG00000062598 ENSG00000158321 ENSG00000197386 ENSG00000292254 ENSG00000178568 PMC7707960__F1 Regulation and interaction of Rac1-related signaling pathways at the postsynaptic terminal ENSG00000062598 ENSG00000158321 ENSG00000008086 ENSG00000292254 PMC7218999__F7 Protein-protein interaction analysis based on STRING with an interaction confidence score (0.400) ENSG00000005882 ENSG00000149273 ENSG00000078070 ENSG00000163541 ENSG00000085662 ENSG00000116030 ENSG00000146676 PMC8440935__F4 Spermine-Related DNA Hypermethylation and Elevated Expression of Genes for Collagen Formation are Susceptible Factors for Chemotherapy-Induced Hand-Foot Syndrome in Chinese Colorectal Cancer Patients ENSG00000197576 ENSG00000129167 ENSG00000099810 ENSG00000116984 PMC4945713__F3 Molecular and cellular neurocardiology: development, and cellular and molecular adaptations to heart disease ENSG00000128342 PMC8263651__F8 Mortalin maintains breast cancer stem cells stemness via activation of Wnt/GSK3B/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4821805__F1 Evolution of haem biosynthetic and degradative pathways ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000256269 ENSG00000188690 PMC7883771__F3 RA signaling and OFCs ENSG00000095596 ENSG00000184254 ENSG00000003137 ENSG00000281324 ENSG00000142599 ENSG00000164690 PMC5142116__F1 Mutations in PROSC Disrupt Cellular Pyridoxal Phosphate Homeostasis and Cause Vitamin-B6-Dependent Epilepsy ENSG00000291814 ENSG00000108924 ENSG00000105516 ENSG00000167074 PMC9582522__F3 Brain-gut-muscle axis in human health and energy homeostasis ENSG00000120833 ENSG00000163235 ENSG00000142166 ENSG00000106546 PMC9582522__F2 Brain-gut-muscle axis in human health and energy homeostasis ENSG00000134070 ENSG00000184216 PMC5503659__F1 Roles of long noncoding RNAs in colorectal cancer metastasis PMC4885862__F4 Survival strategies used by E ENSG00000140564 ENSG00000069869 ENSG00000122218 ENSG00000136869 PMC4885862__F3 Hacker within! Ehrlichia chaffeensis Effector Driven Phagocyte Reprogramming Strategy ENSG00000183283 ENSG00000281324 ENSG00000117153 ENSG00000163251 ENSG00000111237 ENSG00000168264 ENSG00000102312 ENSG00000168036 ENSG00000049618 ENSG00000132510 PMC5728441__F1 Found in translation: how preclinical research is guiding the clinical development of the BCL-2-selective inhibitor venetoclax ENSG00000100290 ENSG00000002330 ENSG00000135116 PMC5503659__F3 Roles of long noncoding RNAs in colorectal cancer metastasis ENSG00000165119 ENSG00000136997 ENSG00000026508 ENSG00000168036 ENSG00000171791 ENSG00000124209 PMC3684061__F4 Genetic Risk Factors for Pancreatic Disorders ENSG00000274247 ENSG00000162438 ENSG00000165376 ENSG00000164266 ENSG00000001626 ENSG00000036828 PMC9279633__F1 Pharmacological modulation of autophagy for Alzheimer's disease therapy: Opportunities and obstacles ENSG00000177169 ENSG00000142192 ENSG00000198382 ENSG00000083290 ENSG00000126775 ENSG00000198793 ENSG00000148572 ENSG00000112561 ENSG00000099940 ENSG00000073921 ENSG00000136874 ENSG00000057663 ENSG00000144848 ENSG00000145782 PMC3109860__F4 CHK1 Inhibitors in Combination Chemotherapy ENSG00000143799 ENSG00000149311 ENSG00000175054 ENSG00000291971 PMC8007787__F1 Reverse transsulfuration pathway and inputs from associated pathways ENSG00000205221 PMC4383754__F1 Cholesterol synthesis and metabolism in the brain ENSG00000116133 ENSG00000172893 ENSG00000113161 ENSG00000141458 PMC8268312__F3 Innate Immune Response to SARS-CoV-2 Infection: From Cells to Soluble Mediators ENSG00000088888 ENSG00000105397 ENSG00000115415 PMC9173833__F6 SARS-CoV-2 infection impairs the insulin/IGF signaling pathway in the lung, liver, adipose tissue, and pancreatic cells via IRF1 ENSG00000125347 PMC8268312__F1 Innate Immune Response to SARS-CoV-2 Infection: From Cells to Soluble Mediators ENSG00000088888 ENSG00000130234 ENSG00000184012 ENSG00000172936 PMC2939656__F4 Complement/Coagulation pathway activation ENSG00000110799 ENSG00000181104 ENSG00000203710 ENSG00000244731 ENSG00000115718 ENSG00000122194 ENSG00000178726 ENSG00000185010 ENSG00000104368 ENSG00000236625 ENSG00000184500 ENSG00000180210 ENSG00000126218 ENSG00000101981 ENSG00000117525 ENSG00000011422 ENSG00000164344 ENSG00000039537 ENSG00000113600 ENSG00000088926 ENSG00000166278 ENSG00000117322 ENSG00000057593 ENSG00000175899 ENSG00000080618 ENSG00000198734 PMC9372463__F2 Influence of metabolic syndrome on age-related hearing loss from the perspective of mitochondrial dysfunction ENSG00000096717 ENSG00000142082 PMC3563405__F1 represents the melanin synthesis in human, plants, fungi and bacteria starting from tyrosine whereas; (B & C) shows melanogenesis from secondary metabolites in fungi and bacteria respectively ENSG00000080166 ENSG00000099194 ENSG00000107165 PMC6329659__F4 Trax: A versatile signaling protein plays key roles in synaptic plasticity and DNA repair ENSG00000188486 ENSG00000149311 PMC7273800__F3 Gene–gene networks generated by pathway analysis from the 17-gene set ENSG00000136011 ENSG00000109452 ENSG00000105472 ENSG00000164761 ENSG00000255974 ENSG00000144648 ENSG00000111729 ENSG00000136842 ENSG00000121351 ENSG00000198604 ENSG00000160179 ENSG00000109103 ENSG00000196233 ENSG00000292254 PMC11856986__F6 Associations between stroke and vascular dementia combing Mendelian randomization with network pharmacology ENSG00000167601 ENSG00000019991 ENSG00000169291 ENSG00000002330 ENSG00000157764 ENSG00000163235 ENSG00000121879 ENSG00000168610 ENSG00000146648 PMC6039250__F5 NRF2 and the hallmarks of cancer ENSG00000284320 ENSG00000065833 ENSG00000065911 ENSG00000169710 ENSG00000146733 ENSG00000023909 ENSG00000115419 PMC7923894__F2 Investigating the Convergent Mechanisms between Major Depressive Disorder and Parkinson's Disease ENSG00000145321 ENSG00000136869 ENSG00000171885 PMC8897867__F1 Activation of cryptic xylose metabolism by a transcriptional activator Znf1 boosts up xylitol production in the engineered Saccharomyces cerevisiae lacking xylose suppressor BUD21 gene ENSG00000105708 ENSG00000074800 ENSG00000172005 PMC7920504__F4 Candidate genes for osimertinib resistance presented within cancer-related signal pathway ENSG00000169291 ENSG00000002330 ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000136997 ENSG00000158458 ENSG00000169752 PMC6039250__F2 NRF2 and the hallmarks of cancer ENSG00000100387 ENSG00000113558 ENSG00000105723 ENSG00000079999 PMC7888496__F4 Proposed model of the role of the JAK-STAT signaling pathway in the development of FLHS in chickens ENSG00000242689 ENSG00000168610 ENSG00000196396 PMC8584061__F4 Emerging Importance of Tyrosine Kinase Inhibitors against Cancer: Quo Vadis to Cure? ENSG00000157404 ENSG00000157764 ENSG00000065361 ENSG00000115904 ENSG00000047936 ENSG00000169032 ENSG00000121879 ENSG00000179295 ENSG00000122025 ENSG00000066468 ENSG00000110395 ENSG00000160867 ENSG00000134853 ENSG00000143622 ENSG00000077782 ENSG00000146648 ENSG00000178568 ENSG00000196712 ENSG00000140443 PMC3270095__F4 Regulatory network for PACAP-responsive genes ENSG00000128272 ENSG00000159388 ENSG00000136826 PMC5890889__F4 Proposed ferritin-mediated feed-forward inflammatory loop ENSG00000177575 ENSG00000239732 PMC4910120__F4 Therapeutics in development target the IFN pathway in SLE ENSG00000213918 ENSG00000239732 ENSG00000105397 ENSG00000172936 PMC4910120__F3 Overlapping type I, II and III IFN signaling pathways ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000147896 PMC9686445__F9 Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations ENSG00000183625 ENSG00000006606 PMC9686445__F6 Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations ENSG00000120088 PMC4397892__F2 Inhibition of the classical apoptosis and autophagy pathway by Gamma-herpesvirus proteins ENSG00000198382 ENSG00000026103 PMC6683665__F5 Interplay between shrimp NFKB pathways and WSSV ENSG00000172936 ENSG00000175104 PMC8771831__F3 Melatonin in the treatment of type 2 diabetes mellitus and Alzheimer's disease ENSG00000169047 PMC6683665__F4 Comparison of the shrimp IMD pathways (A) and Drosophila IMD pathways (B) and Human TNFR signaling (C) ENSG00000102871 ENSG00000157625 ENSG00000168040 PMC6683665__F3 Positive and negative regulatory events in shrimp Toll pathways ENSG00000172936 ENSG00000175104 PMC12090863__F1 Paclitaxel, interferons and functional reprogramming of tumor-associated macrophages in optimized chemo-immunotherapy ENSG00000163464 ENSG00000169248 ENSG00000169245 ENSG00000186810 ENSG00000111537 ENSG00000138755 ENSG00000189403 ENSG00000136869 ENSG00000121966 PMC6097677__F1 Trans-chalcone increases p53 activity via DNAJB1/HSP40 induction and CRM1 inhibition ENSG00000132646 ENSG00000112378 PMC11065698__F1 5-LO-dependent oxylipin formation from ARA, EPA and DHA ENSG00000283887 ENSG00000085871 PMC3999940__F3 Case study of the RegPhos-discovered phosphorylation networks involved in BCR signaling pathway ENSG00000177455 ENSG00000095585 ENSG00000163624 ENSG00000110395 ENSG00000186716 ENSG00000010671 PMC3177754__F4 RIG-I Like Receptors and Their Signaling Crosstalk in the Regulation of Antiviral Immunity ENSG00000167207 ENSG00000187796 ENSG00000125538 PMC6038340__F8 Intra-pathway feedbacks and BRAF/MEK growth-inhibitory synergism ENSG00000157764 ENSG00000146648 PMC7377942__F7 Mechanism of metformin‐mediated improvement of mouse oocyte apoptosis defects induced by arecoline ENSG00000132906 ENSG00000164305 PMC9113573__F6 Proposed mechanism by which proHp inhibits the TGF-Beta-induced EMT in SK-Hep1 liver cancer cells ENSG00000170365 ENSG00000170558 PMC10031043__F1 Maintenance of genome integrity by the late-acting cytoplasmic iron-sulfur assembly (CIA) complex ENSG00000155229 ENSG00000138346 ENSG00000132781 ENSG00000103245 ENSG00000144021 ENSG00000122873 ENSG00000146143 ENSG00000188566 ENSG00000177084 ENSG00000145354 ENSG00000166595 PMC11560026__F11 Mechanism by which SH3KBP1 impairs PRRSV replication, created in BioRender ENSG00000183735 ENSG00000088888 ENSG00000121060 PMC7604490__F2 Genetic pathways implicated in vascular anomalies ENSG00000157404 ENSG00000156049 ENSG00000157764 ENSG00000198793 ENSG00000088256 ENSG00000196712 PMC1288263__F2 Mammalian sex determination: a molecular view ENSG00000125398 ENSG00000168066 PMC3764474__F1 SIRT1-dependent deacetylation of substrate proteins ENSG00000105835 ENSG00000157064 ENSG00000173614 ENSG00000096717 PMC7600400__F2 Reactive oxygen species (ROS) removal and effects ENSG00000112992 ENSG00000105227 PMC5390489__F5 Metabolic switch between MEP and MEC ENSG00000112977 PMC3290818__F1 TLR signalling pathway ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC6636231__F2 Proposed working model of RGS proteins in the regulation of the Ca2+ oscillation-NFATc1 signal pathway for osteoclast (OC) differentiation ENSG00000148908 ENSG00000170909 ENSG00000101307 ENSG00000131196 ENSG00000159788 PMC11889778__F1 NaHS@Cy5@MS@SP nanoparticles improve rheumatoid arthritis by inactivating the Hedgehog signaling pathway through sustained and targeted release of H2S into the synovium ENSG00000164690 ENSG00000128602 PMC9274608__F3 Regulatory mechanisms and potential medical applications of HNF1A-AS1 in cancers ENSG00000167565 ENSG00000065559 PMC6332435__F1 An overview of cellular endocytic mechanisms ENSG00000070831 ENSG00000143761 ENSG00000165527 PMC9274608__F2 Regulatory mechanisms and potential medical applications of HNF1A-AS1 in cancers ENSG00000115507 ENSG00000168036 PMC8198078__F2 Elevating the Levels of Calcium Ions Exacerbate Alzheimer’s Disease via Inducing the Production and Aggregation of Beta-Amyloid Protein and Phosphorylated Tau ENSG00000144935 ENSG00000167323 ENSG00000198838 ENSG00000293604 ENSG00000198626 PMC9369367__F1 Harnessing the Power of Purple Sweet Potato Color and Myo-Inositol to Treat Classic Galactosemia ENSG00000128272 ENSG00000144895 PMC3351834__F2 Transcriptional changes in TGFB1 signaling pathway ENSG00000121989 ENSG00000157077 ENSG00000105329 ENSG00000139269 ENSG00000163083 ENSG00000156574 ENSG00000108443 ENSG00000205250 ENSG00000137801 ENSG00000169231 ENSG00000175634 ENSG00000105664 ENSG00000039319 ENSG00000186340 ENSG00000175189 ENSG00000113558 ENSG00000136997 ENSG00000116985 ENSG00000133740 ENSG00000183682 ENSG00000283060 ENSG00000172201 ENSG00000104899 ENSG00000137834 ENSG00000183691 ENSG00000120693 ENSG00000134363 ENSG00000111537 ENSG00000143768 ENSG00000100387 ENSG00000198176 ENSG00000135409 ENSG00000113296 ENSG00000164093 ENSG00000204217 ENSG00000114739 PMC8905584__F7 To detect potential pathways and target genes in infantile Pompe patients using computational analysis ENSG00000087095 ENSG00000095739 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000148175 ENSG00000196470 ENSG00000185269 PMC8496196__F9 CDK14 Promotes Axon Regeneration by Regulating the Noncanonical Wnt Signaling Pathway in a Kinase-Independent Manner ENSG00000070831 ENSG00000058091 PMC7323084__F4 Rationale for targeting complement in COVID‐19 ENSG00000130234 ENSG00000197405 PMC8047423__F1 Complex regulation of HSC – and possibly hibernators – cell cycle entry ENSG00000177169 ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 ENSG00000114315 PMC8465370__F5 Insights into Alexandrium minutum Nutrient Acquisition, Metabolism and Saxitoxin Biosynthesis through Comprehensive Transcriptome Survey ENSG00000122966 ENSG00000036473 ENSG00000145020 PMC3177754__F3 RIG-I Like Receptors and Their Signaling Crosstalk in the Regulation of Antiviral Immunity ENSG00000121060 PMC6269465__F1 Effect of SPPL2a deficiency on IFNG machinery ENSG00000138600 ENSG00000134982 PMC6475670__F5 Tumor necrosis factorA signaling in gastric cancer ENSG00000102871 ENSG00000056558 ENSG00000168040 ENSG00000127191 PMC4043736__F3 Patterns of Gene Expression Associated with Pten Deficiency in the Developing Inner Ear ENSG00000069482 ENSG00000187017 ENSG00000274665 PMC7870860__F1 Central role of self-nucleic acids in obesity-mediated metaflammation ENSG00000162711 ENSG00000239732 ENSG00000164430 ENSG00000163568 ENSG00000189403 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC7926708__F8 Brief overview of the autophagy pathway, which is a catabolic process that includes a specific intracellular cargo, such as organelles or endosomal contents that are intended for degradation ENSG00000177169 ENSG00000196455 ENSG00000144848 PMC8895457__F7 Targeting mitochondrial respiration and the BCL2 family in high‐grade MYC‐associated B‐cell lymphoma ENSG00000136997 ENSG00000171791 PMC6475670__F4 Interaction network showing miRNAs and their predicted and validated targets ENSG00000077150 ENSG00000109320 ENSG00000102871 ENSG00000127191 ENSG00000064012 ENSG00000164305 PMC5377794__F6 Diagrams demonstrating the processing of Okazaki fragments ENSG00000138346 ENSG00000177084 PMC9285942__F1 WNT/B‐catenin dependent transcription: A tissue‐specific business ENSG00000134982 ENSG00000168036 PMC7886502__F1 Regulatory effects of the estrogen-BDNF-mTORC1 signaling pathway in depression PMC3588029__F3 Regulation of PGC-1A—this schematic represents the relationship between nutrition, circadian clock and other regulatory factors involved in post-translational modification of PGC-1A and its consequent impact on metabolic genes and aging ENSG00000100811 ENSG00000105835 ENSG00000096717 PMC8511346__F1 Sleep and Diet: Mounting Evidence of a Cyclical Relationship ENSG00000139287 ENSG00000129167 PMC3790664__F1 Comparing feedback mechanisms in morphogen signaling ENSG00000162496 ENSG00000138798 PMC6980728__F3 NAD+ biosynthetic pathways and model for SARM1-mediated degeneration ENSG00000105835 ENSG00000123572 ENSG00000278488 ENSG00000157064 ENSG00000173614 PMC8320431__F1 Regulatory Roles of GRK2 in Endothelial Cell Activity and Pathological Angiogenesis ENSG00000170989 PMC3138532__F1 HNSCC tumor microenvironment ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000168610 ENSG00000146648 ENSG00000140443 PMC2194763__F5 Cell cycle pathway diagram obtained from GenMAPP (Gene Map Annotator and Pathway Profiler, Gladstone Institutes, University of San Francisco, San Francisco, CA [38] ENSG00000105329 ENSG00000184182 ENSG00000197629 ENSG00000135476 ENSG00000145386 ENSG00000118971 ENSG00000166851 ENSG00000134480 ENSG00000183765 ENSG00000175054 ENSG00000116670 ENSG00000204634 ENSG00000123374 ENSG00000139687 ENSG00000253729 ENSG00000170027 ENSG00000164109 ENSG00000101224 ENSG00000117399 ENSG00000149311 ENSG00000145604 ENSG00000094804 ENSG00000134057 ENSG00000198176 ENSG00000156970 ENSG00000132646 ENSG00000149554 ENSG00000147082 ENSG00000080839 ENSG00000175305 PMC7155752__F3 Signal transduction in the early Drosophila follicle stem cell lineage ENSG00000112210 ENSG00000128602 PMC7155752__F2 Signal transduction in the early Drosophila follicle stem cell lineage ENSG00000087245 ENSG00000134982 ENSG00000146648 PMC8306262__F4 Statins: a repurposed drug to fight cancer ENSG00000167468 ENSG00000197429 PMC8306262__F3 Statins: a repurposed drug to fight cancer ENSG00000130164 ENSG00000163914 ENSG00000197429 ENSG00000113161 PMC4573392__F1 Emerging concepts in the regulation of hematopoiesis by inflammatory signaling ENSG00000178860 ENSG00000111537 ENSG00000168610 PMC8122924__F2 Lipin-1, a Versatile Regulator of Lipid Homeostasis, Is a Potential Target for Fighting Cancer ENSG00000169047 ENSG00000140443 PMC9445272__F8 CDK9 binds and activates SGK3 to promote cardiac repair after injury via the GSK-3B/Beta-catenin pathway ENSG00000136807 ENSG00000168036 PMC7242365__F4 GWSS host support of nutritional metabolisms in Sulcia-GWSS and Baumannia ENSG00000205221 ENSG00000144644 ENSG00000171759 ENSG00000138621 ENSG00000068120 ENSG00000127125 PMC8635159__F3 An Overview of Glycosylation and its Impact on Cardiovascular Health and Disease ENSG00000100522 ENSG00000198408 PMC5479992__F1 Iron homeostasis ENSG00000010704 ENSG00000182511 ENSG00000106327 ENSG00000105697 PMC7663173__F5 YZT-mediated network analysis reveals UPS as potential target ENSG00000084093 ENSG00000137275 ENSG00000036672 ENSG00000157423 ENSG00000285246 ENSG00000168811 ENSG00000149187 ENSG00000185883 ENSG00000150991 ENSG00000186847 ENSG00000263528 ENSG00000115353 ENSG00000048028 PMC7058704__F2 Autophagy regulation under various stresses ENSG00000188554 ENSG00000144848 ENSG00000147133 PMC3926866__F1 Diagram of the steroid hormone biosynthetic pathway in the human adrenal cortex ENSG00000203859 ENSG00000179142 PMC7058704__F1 Autophagy process ENSG00000152348 ENSG00000123395 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC8348198__F3A R-loop modulated epigenetic regulation in T helper cells mechanistically associates coronary artery disease and non-small cell lung cancer ENSG00000108702 ENSG00000140992 ENSG00000179934 ENSG00000168329 ENSG00000105835 ENSG00000089157 ENSG00000274736 ENSG00000171791 ENSG00000121807 ENSG00000163734 ENSG00000169429 ENSG00000164400 ENSG00000115594 ENSG00000140443 ENSG00000062485 ENSG00000137033 ENSG00000108342 ENSG00000124391 ENSG00000068028 ENSG00000169245 ENSG00000163235 ENSG00000102245 ENSG00000112115 ENSG00000146648 ENSG00000115009 ENSG00000107562 ENSG00000138798 ENSG00000163739 ENSG00000183625 ENSG00000115904 ENSG00000197272 ENSG00000112715 ENSG00000121879 ENSG00000125538 ENSG00000108688 ENSG00000181374 ENSG00000006606 ENSG00000113525 ENSG00000106178 ENSG00000081041 ENSG00000115008 ENSG00000275718 ENSG00000157764 ENSG00000099985 ENSG00000273686 ENSG00000110324 ENSG00000112116 ENSG00000108691 ENSG00000108700 ENSG00000164136 ENSG00000184371 ENSG00000243646 ENSG00000275095 ENSG00000136689 PMC8877168__F4 The NFKB Signaling Pathway Inhibitor BAY11-7082 in the Replication of ASFV ENSG00000077150 ENSG00000125538 ENSG00000056558 ENSG00000143839 ENSG00000073756 ENSG00000277943 PMC8408990__F2 Transcriptome-wide association study of Alzheimer’s disease using prediction models of relevant tissues identifies novel candidate susceptibility genes ENSG00000130208 ENSG00000130202 ENSG00000184831 ENSG00000198087 ENSG00000120885 ENSG00000161929 ENSG00000213413 ENSG00000267467 PMC3391249__F8 Defence Signalling Triggered by Flg22 and Harpin Is Integrated into a Different Stilbene Output in Vitis Cells ENSG00000178860 ENSG00000143631 PMC5335504__F9 Proposed model for the role of ADAP2 in antiviral response ENSG00000183735 ENSG00000088888 ENSG00000184060 ENSG00000131323 PMC8172903__F1 STING1 network regulates autophagy and cell death ENSG00000164430 ENSG00000109320 PMC6436758__F7 Cellular response to small molecules that selectively stall protein synthesis by the ribosome ENSG00000152684 ENSG00000291534 ENSG00000100325 ENSG00000173545 ENSG00000165525 ENSG00000138303 ENSG00000242372 PMC8172903__F3 STING1 network regulates autophagy and cell death ENSG00000132906 ENSG00000183735 ENSG00000164430 ENSG00000109320 ENSG00000120868 ENSG00000168040 ENSG00000168404 ENSG00000064012 ENSG00000164305 ENSG00000285379 PMC8172903__F2 STING1 network regulates autophagy and cell death ENSG00000177169 ENSG00000183735 ENSG00000198793 ENSG00000284099 ENSG00000157954 ENSG00000057663 PMC11854789__F1 Mechanism and Applications of Vagus Nerve Stimulation ENSG00000135414 ENSG00000168610 PMC4658161__F7 Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NFKB Signaling ENSG00000064655 ENSG00000285152 PMC2722148__F1 MAPK transduction signaling pathway ENSG00000066468 ENSG00000095015 PMC3814597__F2 General activation of interferonB (IFNB) transcription and induction of IFN-stimulated genes ENSG00000213928 ENSG00000105397 ENSG00000115415 PMC8306508__F5 Acquisition of New Migratory Properties by Highly Differentiated CD4+CD28null T Lymphocytes in Rheumatoid Arthritis Disease ENSG00000117525 ENSG00000070831 ENSG00000134982 ENSG00000138443 ENSG00000181104 ENSG00000198670 ENSG00000154096 PMC7060471__F2 Pharmacological manipulation of the activity of Wnt/B‐catenin signaling pathway ENSG00000134982 ENSG00000102312 ENSG00000168036 ENSG00000173273 PMC7060471__F1 A, Position frequency matrix of the T‐cell factor (TCF) motif was obtained from the JASPAR database (http://jaspar.genereg.net) ENSG00000168036 ENSG00000084110 PMC3824408__F1 Unveiling the last missing link of the cardiolipin synthetic pathway in mitochondria ENSG00000167311 ENSG00000163624 ENSG00000087157 ENSG00000184207 PMC5088199__F1 Cellular pathways currently being targeted in the treatment of endometrial cancer (EC) and the potential actionable genes in EC identified via Next Generation Sequencing (NGS) ENSG00000117713 ENSG00000002330 ENSG00000115350 ENSG00000100479 ENSG00000077514 ENSG00000105568 ENSG00000121879 ENSG00000106628 ENSG00000177084 ENSG00000109670 PMC4079587__F5 Interaction of kisspeptin, estrogen and BMP-4 in regulation of GnRH production by GT1-7 cells ENSG00000170365 ENSG00000137834 PMC4726671__F1 Hepatitis C virus life cycle ENSG00000130164 ENSG00000163914 ENSG00000015520 ENSG00000110651 ENSG00000146648 PMC4077471__F3 Examples of pathway engineering and combinatorial biosynthesis to generate new analogs: A ENSG00000084110 ENSG00000135605 PMC9126881__F8 M2 macrophage-derived extracellular vesicles (EVs) on the development of ankylosing spondylitis (AS) through by transferring of microRNA-22-3p ENSG00000188064 ENSG00000132326 ENSG00000168036 PMC8462485__F9 Oridonin Prolongs the Survival of Mouse Cardiac Allografts by Attenuating the NFKB/NLRP3 Pathway ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC5499174__F1 The assayed components of the IIS/TOR pathway and their proposed interactions in D ENSG00000136997 ENSG00000170145 PMC3745370__F8 High expression of the ppGalNAc-T13 gene enhances cancer metastasis by formation of trimeric Tn antigen ENSG00000115884 ENSG00000150093 ENSG00000155657 PMC4276719__F10 Fatty acid metabolism in bacteria ENSG00000168040 ENSG00000100294 PMC7796222__F5 Postulated metabolic pathway of Alpha-PHP and 4F-Alpha-PVP ENSG00000180210 ENSG00000117525 ENSG00000198734 PMC4867327__F9 Schematic diagram illustrating lipid droplet formation, VLDL secretion, and pathways involving hepatic inflammation ENSG00000162711 ENSG00000042832 ENSG00000138823 ENSG00000125538 ENSG00000173599 ENSG00000102172 ENSG00000133027 PMC2864659__F6 APE1 has dual roles in redox and DNA repair ENSG00000108924 PMC9197245__F7 Strontium Regulates the Proliferation and Differentiation of Isolated Primary Bovine Chondrocytes via the TGFB/SMAD Pathway ENSG00000139219 ENSG00000170365 ENSG00000105329 ENSG00000118785 ENSG00000162551 ENSG00000157766 ENSG00000120693 PMC6491380__F9 Reversion of HIV-1 latency regulated by DCs ENSG00000124102 ENSG00000163624 ENSG00000110651 ENSG00000010278 ENSG00000112149 PMC8613610__F2 Updates of Podocyte Lipid Metabolism in Proteinuric Kidney Disease ENSG00000173599 ENSG00000103222 ENSG00000160179 ENSG00000183018 ENSG00000062485 PMC6652211__F6 Possible EPO signaling pathway ENSG00000196411 ENSG00000186716 ENSG00000187266 ENSG00000124181 PMC2683382__F2 Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites ENSG00000137033 ENSG00000172936 ENSG00000145777 ENSG00000166090 ENSG00000056736 ENSG00000175104 ENSG00000168610 ENSG00000135605 PMC3730428__F8 Schematic diagram summarizing the key findings ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000064012 ENSG00000164305 PMC3906322__F2 STAT2 and IRF9 ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000140279 ENSG00000132478 ENSG00000107201 ENSG00000140274 ENSG00000175104 ENSG00000142166 PMC6163297__F6 Schematic drawing of the possible signalling pathways regulated by PACAP in bone formation ENSG00000170365 ENSG00000164690 ENSG00000128602 ENSG00000163501 PMC5814345__F6 Ezrin mediates both HGF/Met autocrine and non-autocrine signaling-induced metastasis in melanoma ENSG00000019991 ENSG00000185591 PMC7961955__F7 Common signaling pathways in liver disease (primarily HCC) and the kinase inhibitors aimed at these pathways ENSG00000122025 ENSG00000167601 ENSG00000157404 ENSG00000291971 ENSG00000198793 ENSG00000146648 PMC2080843__F5 Simulation of the Apoptosis pathway under FasL stimulation (black starred line), bacterial only (red circled line) and both (blue triangled line) ENSG00000132906 ENSG00000064012 ENSG00000164305 PMC5986551__F5 Network analysis of differentially expressed genes in glioma cells exposed to exosomes ENSG00000108691 ENSG00000125538 ENSG00000108342 ENSG00000165606 ENSG00000164400 ENSG00000169429 ENSG00000116183 ENSG00000143184 ENSG00000145861 PMC4977841__F1 Hedgehog signaling inhibition by the small molecule Smoothened inhibitor GDC-0449 in the bone forming prostate cancer xenograft MDA PCa 118b ENSG00000164690 ENSG00000128602 PMC10151263__F8 Grain-sized moxibustion at Zusanli (ST36) promotes hepatic autophagy in rats with hyperlipidemia by regulating the ULK1 and TFEB expression through the AMPK/mTOR signaling pathway ENSG00000177169 ENSG00000198793 ENSG00000112561 ENSG00000196689 PMC3360921__F8 IQGAP1 regulates cell homeostasis through mTORC1 ENSG00000070831 ENSG00000140575 ENSG00000138798 ENSG00000198793 PMC5986551__F2 MS and network analysis of hypoxic exosomal proteome ENSG00000160789 ENSG00000047410 ENSG00000105835 ENSG00000116521 ENSG00000030582 ENSG00000181163 ENSG00000100129 ENSG00000163064 ENSG00000196591 ENSG00000170606 ENSG00000169710 ENSG00000197451 ENSG00000166147 ENSG00000172037 ENSG00000137801 ENSG00000107581 ENSG00000004478 ENSG00000077150 ENSG00000138663 ENSG00000149968 ENSG00000184110 ENSG00000149273 ENSG00000184432 ENSG00000140464 ENSG00000164619 ENSG00000253729 ENSG00000135919 ENSG00000185088 ENSG00000108298 ENSG00000165119 ENSG00000164587 ENSG00000198242 ENSG00000158941 ENSG00000177733 ENSG00000049860 ENSG00000274442 ENSG00000278270 ENSG00000105669 ENSG00000122566 ENSG00000134013 ENSG00000175166 ENSG00000125844 ENSG00000130147 ENSG00000106263 ENSG00000130175 PMC6235777__F1 Graphical representation of IFNG signaling pathway ENSG00000112977 ENSG00000109321 ENSG00000291971 ENSG00000144857 ENSG00000137055 PMC8016451__F8 Schematic diagram showing the mechanism by which Rspo1/Rspo3-LGR4 signaling inhibits hepatic cholesterol synthesis ENSG00000112972 ENSG00000130164 ENSG00000113161 PMC9025063__F6 Genome Integrity and Neurological Disease ENSG00000149311 ENSG00000138346 ENSG00000101773 ENSG00000154920 ENSG00000197299 ENSG00000051180 ENSG00000310560 ENSG00000139618 PMC11648684__F10 Main mechanisms involved in the regulation of oxidative stress by m6A ENSG00000145388 ENSG00000092096 ENSG00000178741 ENSG00000154265 ENSG00000173064 ENSG00000146457 ENSG00000128191 ENSG00000165819 ENSG00000106459 ENSG00000079999 PMC9025063__F5 Genome Integrity and Neurological Disease ENSG00000105486 ENSG00000177084 ENSG00000136936 PMC10198048__F7 Working model of how Cas regulates osteoclastogenesis ENSG00000164935 ENSG00000100985 ENSG00000175104 ENSG00000131196 ENSG00000143387 PMC4499510__F1 WNT/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000173273 PMC9025063__F4 Genome Integrity and Neurological Disease ENSG00000143799 ENSG00000105486 ENSG00000132646 PMC8798237__F4 Key genes involved in cell cycle arrest and DNA damage repair identified in anaplastic thyroid carcinoma using integrated bioinformatics analysis ENSG00000149311 ENSG00000175054 ENSG00000179091 ENSG00000136997 ENSG00000042286 ENSG00000123374 ENSG00000164305 PMC2639448__F1 Intrafollicular predictors and regulators of oocyte quality within the oocyte–somatic cell regulatory loop ENSG00000170365 ENSG00000170961 ENSG00000164404 ENSG00000130385 ENSG00000073756 PMC5445212__F1 Endosomal transport channels and regulation of lipoprotein-derived cholesterol in hepatocytes.In many models, it was thought that cholesterol from all sources would enter a common regulatory pool before subsequent trafficking and regulatory steps ENSG00000138075 ENSG00000130164 ENSG00000113161 ENSG00000120437 ENSG00000143921 PMC8047423__F2 Molecular mechanism governing cell quiescence and torpidity in contrast with cell proliferation and euthermia ENSG00000005882 ENSG00000198793 ENSG00000140464 ENSG00000143995 PMC11648684__F11 M6A is involved in regulating the immune function of innate immune cells neutrophils, macrophages, NK cells and adaptive immune cells T cells and B cells ENSG00000145388 ENSG00000041982 ENSG00000060237 ENSG00000198492 ENSG00000091542 ENSG00000173572 ENSG00000165819 PMC140192__F7 Epidermal growth factor signaling via Ras controls the Smad transcriptional co-repressor TGIF ENSG00000156574 ENSG00000146648 PMC4884928__F4 Systematic drug perturbations on cancer cells reveal diverse exit paths from proliferative state ENSG00000188786 ENSG00000117153 ENSG00000138798 ENSG00000157601 ENSG00000168036 ENSG00000112118 ENSG00000112715 ENSG00000092820 ENSG00000179295 ENSG00000274619 ENSG00000150782 ENSG00000213949 ENSG00000165841 ENSG00000116688 ENSG00000170266 ENSG00000113558 ENSG00000115138 ENSG00000139687 ENSG00000104365 ENSG00000142192 ENSG00000125148 ENSG00000130826 ENSG00000143878 ENSG00000285433 ENSG00000073756 ENSG00000276561 ENSG00000186298 ENSG00000102710 ENSG00000100029 ENSG00000109814 ENSG00000055163 ENSG00000177606 ENSG00000114268 ENSG00000184371 ENSG00000142089 ENSG00000092841 ENSG00000111331 ENSG00000164690 ENSG00000175792 ENSG00000132341 PMC3159954__F3 Antiretroviral Therapy Down-regulates Innate Antiviral Response Genes in Patients with AIDS in Sub-Saharan Africa ENSG00000187608 ENSG00000100387 PMC3159954__F2 Antiretroviral Therapy Down-regulates Innate Antiviral Response Genes in Patients with AIDS in Sub-Saharan Africa ENSG00000213928 ENSG00000105397 ENSG00000230034 PMC7763666__F5 Wingless-type (WNT) signaling pathway ENSG00000087095 ENSG00000291971 ENSG00000134982 ENSG00000177606 ENSG00000104332 PMC8798237__F3 Key genes involved in cell cycle arrest and DNA damage repair identified in anaplastic thyroid carcinoma using integrated bioinformatics analysis ENSG00000145604 ENSG00000179091 ENSG00000132646 ENSG00000172005 ENSG00000115942 ENSG00000123374 ENSG00000205250 ENSG00000277273 ENSG00000276876 ENSG00000093009 PMC4815022__F4 Identified signaling pathways downstream to glycine in NSCs ENSG00000156049 ENSG00000156076 ENSG00000149212 ENSG00000152495 ENSG00000164161 ENSG00000164690 ENSG00000064012 ENSG00000124762 ENSG00000285069 ENSG00000080546 PMC4884928__F5 Systematic drug perturbations on cancer cells reveal diverse exit paths from proliferative state ENSG00000132906 ENSG00000213928 ENSG00000187608 ENSG00000115415 ENSG00000142089 ENSG00000168610 ENSG00000276561 PMC7596088__F3 Role of TGFB, IL-6, and IL-1B signaling pathways in PDAC EMT ENSG00000107562 ENSG00000125538 ENSG00000115009 PMC5567228__F6 Wnt/FZD4 signaling pathways through the interaction of miR-204 with FZD4-miR-SNP (rs713065) variant in NSCLC cells ENSG00000004975 ENSG00000087095 ENSG00000156076 ENSG00000281324 ENSG00000105329 ENSG00000134982 ENSG00000291971 ENSG00000168036 ENSG00000143933 ENSG00000104332 ENSG00000196628 ENSG00000157557 ENSG00000136997 ENSG00000026508 PMC8865078__F7 Transforming Growth Factor-Beta-Regulated LncRNA-MUF Promotes Invasion by Modulating the miR-34a Snail1 Axis in Glioblastoma Multiforme ENSG00000110888 PMC8472533__F1 New Player in Neuroblastoma: YAP and Its Role in the Neuroblastoma Microenvironment ENSG00000131023 PMC7559338__F6 Experimental verification of TFAP2C regulating EGFR in A549 cancer cells ENSG00000087510 ENSG00000146648 PMC10759702__F7 Leukocyte differential gene expression prognostic value for high versus low seizure frequency in temporal lobe epilepsy ENSG00000245848 ENSG00000111537 ENSG00000172216 ENSG00000109320 ENSG00000125538 ENSG00000177606 ENSG00000185591 ENSG00000168610 ENSG00000164342 PMC5298863__F4 Intracellular signalling pathways that are activated by insulin and amino acids after feeding and that lead to the activation of translation initiation in the immature skeletal muscle ENSG00000198793 ENSG00000164327 PMC9344793__F3 Cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics ENSG00000138075 ENSG00000135218 ENSG00000130164 ENSG00000160179 ENSG00000120437 ENSG00000075239 ENSG00000143921 ENSG00000213523 PMC6590595__F1 WNT signaling model ENSG00000134982 ENSG00000168036 PMC8577929__F1 Target Sestrin2 to Rescue the Damaged Organ: Mechanistic Insight into Its Function ENSG00000177169 ENSG00000079999 PMC6618143__F3 Macrophage metabolic pathways ENSG00000131473 ENSG00000198829 ENSG00000102794 ENSG00000118520 ENSG00000026103 PMC10375641__F5 Super-enhancers complexes zoom in transcription in cancer ENSG00000136997 ENSG00000146648 PMC11364386__F1 Blockade of secretory vesicle biogenesis provides a therapeutic strategy for targeting cancer ENSG00000113384 ENSG00000011422 ENSG00000173905 ENSG00000017260 PMC4419472__F9 Schematic diagram describing the effect of oroxylin A on the inhibition of p53 degradation through the suppression of PTEN-regulated MDM2 expression ENSG00000142082 PMC8089133__F4 Multi-omics reveals age-related differences in the diaphragm response to mechanical ventilation: a pilot study ENSG00000144063 ENSG00000183735 ENSG00000157625 ENSG00000168040 ENSG00000285200 ENSG00000127191 ENSG00000127948 PMC8452151__F4 Mechanisms that decode combinatorial and temporal codes of pathway activity to achieve stimulus-specific responses ENSG00000171855 ENSG00000221869 ENSG00000162772 PMC9313267__F2 Mechanism and Role of ADAMTS Protein Family in Osteoarthritis ENSG00000105664 ENSG00000146469 ENSG00000007171 PMC8452151__F2 Molecular mechanisms for combinatorial encoding to achieve stimulus-specific responses ENSG00000088888 ENSG00000102871 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000164342 PMC8588641__F7 Umbilical cord blood plasma-derived exosomes as a novel therapy to reverse liver fibrosis ENSG00000125968 PMC2949386__F6 Preclinical Evaluation of Novel Triphenylphosphonium Salts with Broad-Spectrum Activity ENSG00000019991 ENSG00000177606 ENSG00000099942 ENSG00000073756 ENSG00000168610 ENSG00000089159 ENSG00000179295 PMC6110613__F2 Exploiting vita-PAMPs in vaccines ENSG00000125538 ENSG00000115594 PMC4493053__F7 Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition ENSG00000198793 ENSG00000164690 ENSG00000128602 PMC2731733__F5 Cytoskeletal Remodeling: FAK Signaling pathway is enriched for HeLa and TOV edge hits using PIPA but not node hits using HGA enrichment ENSG00000006607 ENSG00000169291 ENSG00000070831 ENSG00000163914 ENSG00000131323 PMC4450261__F1 Activation of the Keap1-Nrf2-ARE pathway by oxidants/electrophiles ENSG00000178573 ENSG00000079999 PMC5945923__F1 Cross talk between E2–estrogen receptorA (ERA) signaling pathways and circadian rhythms in breast cancer ENSG00000087245 ENSG00000291971 ENSG00000132326 PMC7179206__F6 (−)-epicatechin anticancer activity in MDA-MB-231 and MCF-7 cells ENSG00000002330 ENSG00000115317 PMC5528412__F1 Simplified representation of the PI3K signaling pathway ENSG00000124102 ENSG00000109452 PMC5536354__F7 Hox complex activates and potentiates the Epidermal Growth Factor signaling pathway to specify Drosophila oenocytes ENSG00000002330 ENSG00000138798 ENSG00000163914 ENSG00000075891 ENSG00000146648 PMC2722335__F1 Adipocyte lineage commitment and terminal differentiation PMC10706592__F3 TRAIL signaling pathway indicating the therapeutic targets modulated by flavonoid compounds ENSG00000168040 PMC10706592__F1 TRAIL signaling pathway ENSG00000168040 PMC9414016__F1 Dual role of fucosidase in cancers and its clinical potential ENSG00000196968 ENSG00000196371 ENSG00000172728 ENSG00000101346 ENSG00000112699 ENSG00000180549 ENSG00000130383 ENSG00000186866 ENSG00000001036 ENSG00000179163 PMC6295312__F1 Gene-level alterations in muscle-invasive bladder cancer in the context of curated pathways ENSG00000121989 ENSG00000109452 ENSG00000112576 ENSG00000157404 ENSG00000149930 ENSG00000141551 ENSG00000162337 ENSG00000160551 ENSG00000135090 ENSG00000134982 ENSG00000196782 ENSG00000164327 ENSG00000141564 ENSG00000124762 ENSG00000122025 ENSG00000065717 ENSG00000187957 ENSG00000184675 ENSG00000143801 ENSG00000073614 ENSG00000155011 ENSG00000136997 ENSG00000108375 ENSG00000174197 ENSG00000116990 ENSG00000105810 ENSG00000165323 ENSG00000077782 ENSG00000139687 ENSG00000140443 ENSG00000196712 ENSG00000109670 ENSG00000113645 ENSG00000134376 ENSG00000166341 ENSG00000101109 ENSG00000156076 ENSG00000105568 ENSG00000106829 ENSG00000197070 ENSG00000110395 ENSG00000065526 ENSG00000146648 ENSG00000178568 ENSG00000198793 ENSG00000115904 ENSG00000168036 ENSG00000169032 ENSG00000047936 ENSG00000104332 ENSG00000118971 ENSG00000179295 ENSG00000083857 ENSG00000070444 ENSG00000186575 ENSG00000104371 ENSG00000183579 ENSG00000143622 ENSG00000108788 ENSG00000135503 ENSG00000281178 ENSG00000005339 ENSG00000157764 ENSG00000065361 ENSG00000184916 ENSG00000131023 ENSG00000074219 ENSG00000079999 ENSG00000149311 ENSG00000066468 ENSG00000177189 ENSG00000160867 ENSG00000135446 ENSG00000148204 ENSG00000050165 ENSG00000134853 ENSG00000168646 ENSG00000114166 ENSG00000198625 PMC6152364__F4 Relation between mammalian MAPK cascades and other kinases capable to induce cell responses involved in cancer ENSG00000070831 ENSG00000198793 PMC9120629__F1 Complement Dependent Synaptic Reorganisation During Critical Periods of Brain Development and Risk for Psychiatric Disorder ENSG00000039537 ENSG00000113600 ENSG00000166278 ENSG00000182326 ENSG00000062485 ENSG00000236625 PMC7479251__F4 Notch signaling pathway, including targets and drugs that could be employed to inhibit it ENSG00000168214 ENSG00000128917 ENSG00000184916 ENSG00000090932 PMC7479251__F6 Hippo pathway including targets and drugs that could be employed to inhibit it ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC7479251__F5 Sonic Hedgehog canonical signaling, including targets and drugs that could be employed to inhibit it ENSG00000166813 PMC8526190__F1 Neutrophil Extracellular Traps (NETs): Opportunities for Targeted Therapy ENSG00000005381 ENSG00000062485 PMC7479251__F7 TLRs pathway including targets and drugs that could be employed to inhibit it ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC3049553__F1 MAPK pathway activation in melanoma ENSG00000291971 ENSG00000198793 PMC8602415__F7 Transcriptome analysis reveals that long noncoding RNAs contribute to developmental differences between medium-sized ovarian follicles of Meishan and Duroc sows ENSG00000091409 ENSG00000150093 ENSG00000139626 ENSG00000137801 PMC8602415__F6 Transcriptome analysis reveals that long noncoding RNAs contribute to developmental differences between medium-sized ovarian follicles of Meishan and Duroc sows ENSG00000172318 ENSG00000053702 ENSG00000140279 ENSG00000175352 ENSG00000162437 ENSG00000067842 ENSG00000073060 ENSG00000006327 ENSG00000077782 ENSG00000275565 ENSG00000109321 ENSG00000140465 ENSG00000087460 ENSG00000173200 ENSG00000171657 ENSG00000150433 ENSG00000151778 ENSG00000158714 ENSG00000118785 ENSG00000143768 ENSG00000120533 ENSG00000101255 ENSG00000138166 ENSG00000164754 ENSG00000197562 PMC8211227__F3 Schemetic drawing of carbon fixation in photosynthetic process (adapted from KEGG pathway zma00710) ENSG00000151376 ENSG00000005882 ENSG00000082212 PMC3060875__F3 Acute Endotoxin-Induced Thymic Atrophy Is Characterized By Intrathymic Inflammatory and Wound Healing Responses ENSG00000177606 ENSG00000108688 ENSG00000185591 ENSG00000115009 PMC3060875__F5 Acute Endotoxin-Induced Thymic Atrophy Is Characterized By Intrathymic Inflammatory and Wound Healing Responses ENSG00000291603 ENSG00000213658 ENSG00000010810 ENSG00000141968 PMC4959673__F6 HRPII recognition by human brain endothelial cells and the intracellular pathway that leads to BBB leakage ENSG00000125538 ENSG00000172936 ENSG00000162692 PMC8399750__F1 Nrf2 Pathway in Ischemic Stroke: A Review ENSG00000172458 ENSG00000177169 ENSG00000136436 ENSG00000135218 ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC7262827__F6 KEGG pathway analysis of differentially regulated genes in MCF7 cells after treatment with isopicrinine alkaloid, depicting the affected genes that play significant role in cell cycle and cell proliferation ENSG00000145604 ENSG00000132646 ENSG00000135336 ENSG00000123374 ENSG00000205250 ENSG00000277273 ENSG00000276876 PMC9500598__F2 Circular RNAs Involved in the Regulation of the Age-Related Pathways ENSG00000171105 ENSG00000198793 ENSG00000155792 ENSG00000255690 PMC9500181__F1 Molecular mechanism of ferroptosis and its role in the occurrence and treatment of diabetes ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000102967 ENSG00000079999 PMC7262827__F5 KEGG pathway analysis of differentially regulated genes in MCF7 cells after treatment with isopicrinine alkaloid, depicting the affected genes in p53 signaling pathway ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000182511 ENSG00000123374 ENSG00000112378 ENSG00000164305 PMC7602998__F1 Events after colorectal surgery leading to AL ENSG00000197971 ENSG00000125538 ENSG00000172936 ENSG00000171051 PMC3652374__F4 PPARG as a key regulator of lipogenesis in adipocytes and hypothetical major target for inhibitors of insulin-stimulated lipogenesis in obesity ENSG00000111537 ENSG00000125538 ENSG00000026103 PMC7016007__F7 Crosstalk of metabolic pathways in AMD ENSG00000291803 ENSG00000141564 ENSG00000096717 PMC3426783__F4 IPA network analyses were applied to differentially expressed genes in mouse brain after in vivo ketamine exposure ENSG00000124102 ENSG00000130545 ENSG00000197081 ENSG00000109321 ENSG00000169562 ENSG00000091409 ENSG00000106331 ENSG00000134186 ENSG00000176903 ENSG00000288250 ENSG00000129993 ENSG00000125820 ENSG00000165724 ENSG00000001630 ENSG00000158022 ENSG00000198728 ENSG00000185532 PMC4593152__F4 Conditional probability and local structure extracted from the simplified network, for calculating the indirect effect of this specific pathway (NAFLD, GGT1, GGT2, dyslipidemia, hypertension and MetS) PMC3652374__F2 Insulin signalling exerts rapid stimulation of glucose transport as well as fatty acid uptake, synthesis and esterification to triacylglycerol (TG) ENSG00000042832 ENSG00000026103 PMC3652374__F1 Insulin signalling attenuates cAMP-mediated lipolysis at multiple steps in adipocytes ENSG00000166819 ENSG00000138735 ENSG00000171105 ENSG00000042832 ENSG00000106070 ENSG00000169047 PMC5891907__F1 Scheme of the innate immune response to injury ENSG00000108691 ENSG00000172936 ENSG00000136869 PMC5466160__F1 Autophagy pathway ENSG00000177169 ENSG00000152348 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC8800599__F1 Oxidative Stress Signaling Mediated Pathogenesis of Diabetic Cardiomyopathy ENSG00000162711 ENSG00000079999 PMC4533772__F3 Analyses of interactions among SHRSP-specific genes ENSG00000146276 ENSG00000120915 ENSG00000109906 ENSG00000196218 ENSG00000177674 ENSG00000140465 ENSG00000172530 PMC5098802__F2 Injury site-specific targeting of complement inhibitors for treating stroke ENSG00000203710 ENSG00000122194 ENSG00000132693 ENSG00000084774 PMC4765310__F2A Importance of the Non Obese Diabetic (NOD) mouse model in autoimmune diabetes ENSG00000183735 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC3721730__F2 TRAIL-mediated extrinsic pathway of apoptosis ENSG00000061273 ENSG00000168040 PMC11436262__F4 PPM1G participates in the occurrence and development of hepatocellular carcinoma and liver fibrosis via different pathways ENSG00000074181 ENSG00000126457 ENSG00000114315 ENSG00000064012 PMC3721730__F1 Intrinsic and ER pathways of apoptosis ENSG00000002330 PMC11436262__F3 PPM1G-associated signaling pathways ENSG00000125968 PMC4533772__F2 Analyses of interactions among SHR-specific genes ENSG00000100285 ENSG00000120915 ENSG00000109906 ENSG00000213949 ENSG00000198483 ENSG00000117472 ENSG00000078900 ENSG00000019186 ENSG00000177606 ENSG00000145321 ENSG00000177674 ENSG00000269404 ENSG00000001626 PMC11881679__F2 AAT is involved in the regulation of the cell signaling pathways and the pathogenesis of disease ENSG00000172936 ENSG00000157625 ENSG00000168040 ENSG00000175104 ENSG00000127191 PMC5841291__F8 Sotetsuflavone inhibits non-small-cell lung cancer cell invasion and metastasis ENSG00000170558 ENSG00000198793 PMC5083753__F3 Anticancer and analgesic activities of B‐caryophyllene (BCP) and B‐caryophyllene oxide (BCPO) ENSG00000198793 ENSG00000171791 ENSG00000168610 PMC2953155__F5 Model schematic of Nipah virus-triggered DC immune response mechanisms and antagonist activity of the response ENSG00000105397 ENSG00000276561 ENSG00000277943 PMC10471462__F2 Hippo pathway is involved in T cell development ENSG00000117525 ENSG00000150907 ENSG00000114978 ENSG00000049768 ENSG00000168610 PMC6461132__F1 PRR signalling pathways ENSG00000162711 ENSG00000167207 ENSG00000197943 ENSG00000131323 ENSG00000106100 ENSG00000184216 PMC10471462__F1 Hippo pathway is a signaling pathway that regulates the self-renewal and differentiation of hematopoietic stem cells (HSCs) ENSG00000186575 ENSG00000159216 ENSG00000070831 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC6461132__F3 Negative Regulation of PRR-induced signalling ENSG00000162711 ENSG00000007171 PMC10471462__F3 Hippo pathway is involved in megakaryopoiesis (upper panel) and erythropoiesis (bottom panel) ENSG00000163430 ENSG00000174059 PMC4083854__F2 Diagram showing the effects of knockout or blockade of specific elements of the alternative, classical and lectin pathways of complement activation on the pathogenesis of anti-MPO induced murine crescentic glomerulonephritis ENSG00000039537 ENSG00000009724 ENSG00000291559 ENSG00000244731 PMC11019012__F2 Natural products targeting autophagy and apoptosis in NSCLC: a novel therapeutic strategy ENSG00000002330 ENSG00000168040 PMC8087671__F3 Proteomic and phosphoproteomic profiling of shammah induced signaling in oral keratinocytes ENSG00000143799 ENSG00000188486 ENSG00000184254 ENSG00000162711 ENSG00000092439 ENSG00000124256 ENSG00000099985 ENSG00000067057 ENSG00000137275 ENSG00000137033 ENSG00000171791 ENSG00000168040 ENSG00000127191 ENSG00000189403 ENSG00000136869 ENSG00000083799 ENSG00000100504 ENSG00000168404 ENSG00000285379 ENSG00000143258 ENSG00000026103 ENSG00000164342 PMC7813674__F1 NFKB signaling pathway ENSG00000239732 ENSG00000102871 ENSG00000187554 ENSG00000082512 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000175104 ENSG00000127191 ENSG00000184216 ENSG00000164342 PMC8558653__F5 Mucin 1 promotes tumor progression through activating WNT/Beta-catenin signaling pathway in intrahepatic cholangiocarcinoma ENSG00000137673 ENSG00000168036 PMC9646327__F8 Virtual Screening and Network Pharmacology-Based Study to Explore the Pharmacological Mechanism of Clerodendrum Species for Anticancer Treatment ENSG00000140992 ENSG00000291971 ENSG00000198793 ENSG00000121058 ENSG00000087586 ENSG00000121879 ENSG00000164305 ENSG00000139618 ENSG00000183765 ENSG00000012048 ENSG00000082175 ENSG00000128052 ENSG00000164362 ENSG00000026508 ENSG00000100985 ENSG00000146648 ENSG00000113494 PMC3759173__F3A Microarray Analysis in a Cell Death Resistant Glioma Cell Line to Identify Signaling Pathways and Novel Genes Controlling Resistance and Malignancy ENSG00000145362 ENSG00000148346 ENSG00000144802 ENSG00000154589 ENSG00000277263 ENSG00000198626 ENSG00000135341 ENSG00000127863 PMC3469060__F6 Putative mechanisms responsible for UPR activation by CD147 in human HCC cells ENSG00000100811 PMC7526978__F2 Z-nucleic acid-dependent inflammatory signaling pathway ENSG00000124256 ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC8042276__F4 Epigenetic Modifiers: Anti-Neoplastic Drugs With Immunomodulating Potential ENSG00000111537 ENSG00000107485 ENSG00000132510 ENSG00000049768 ENSG00000096717 ENSG00000112115 ENSG00000073861 ENSG00000163517 ENSG00000108840 PMC7924357__F1 Angiogenesis pathways in malignancy and targeted therapies commonly used ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC9059429__F1 Rodent Genetic Models of Ah Receptor Signaling ENSG00000106546 PMC7920551__F8 Model depicting lymph gland progenitor heterogeneity and response to immune challenge ENSG00000213658 ENSG00000164362 PMC3852779__F2 Hepatic genes differentially regulated by 17Beta-trenbolone: Impacts on metabolic pathways ENSG00000051523 ENSG00000161544 ENSG00000142973 ENSG00000262635 ENSG00000197838 ENSG00000179091 ENSG00000117707 ENSG00000143252 ENSG00000001630 ENSG00000019186 ENSG00000036530 ENSG00000198125 ENSG00000005381 ENSG00000121053 ENSG00000135929 PMC6941129__F4 Regulation of the G1/S transition by the Greatwall-Endosulfine-PP2A/Cdc55 pathway in budding yeast ENSG00000261832 ENSG00000123374 PMC9451157__F5 Pathway and mechanism analysis of F1-mediated chemoenzymatic synthesis of benzimidazole ENSG00000244731 PMC4663159__F7 The integration of the DUOX2 system into the intestinal epithelial defense response ENSG00000134982 ENSG00000163739 ENSG00000140279 ENSG00000115009 ENSG00000143954 PMC12109299__F1 HER2 signaling ENSG00000146648 PMC6723600__F1 IL-38 signaling pathways ENSG00000172936 ENSG00000185187 ENSG00000115594 PMC11478363__F5 Research Progress on the Mechanisms of Protocatechuic Acid in the Treatment of Cognitive Impairment ENSG00000132906 ENSG00000115415 ENSG00000065559 ENSG00000172936 ENSG00000171791 ENSG00000169032 ENSG00000096717 ENSG00000164305 PMC6321632__F2 mRNA translation stress feedback to ribosome biogenesis and cell proliferation ENSG00000101751 ENSG00000198793 PMC7367634__F6 Resistance mechanism to vemurafenib ENSG00000198793 ENSG00000196712 PMC8732282__F8 Proposed model depicting the therapeutic mechanism of GRB7-PLK1 axis inhibition to overcome MEKi resistance in KRAS mutant colon cancer cells ENSG00000166851 ENSG00000168610 PMC3905281__F5 Wnt signalling pathway in developing muscle-less humeri ENSG00000107105 ENSG00000185669 ENSG00000168036 ENSG00000184916 ENSG00000146374 ENSG00000292214 ENSG00000103449 ENSG00000107859 ENSG00000116106 ENSG00000167178 ENSG00000155011 ENSG00000108878 ENSG00000026508 ENSG00000154310 ENSG00000164093 ENSG00000180875 ENSG00000116690 ENSG00000147082 PMC11677171__F2 Molecular mechanisms responsible for the suppression of T:B cell cross-talk in inflamed glandular tissues ENSG00000178860 ENSG00000049768 ENSG00000168610 ENSG00000026103 PMC3516044__F3 Changes in the Plasmodium falciparum redox flux network after MB drug action.Notes: Results incorporating the transcription data and experimental mRNA expression data nine hours after incubation with methylene blue are shown ENSG00000188219 PMC3759173__F4A Microarray Analysis in a Cell Death Resistant Glioma Cell Line to Identify Signaling Pathways and Novel Genes Controlling Resistance and Malignancy ENSG00000110031 ENSG00000163565 ENSG00000140044 ENSG00000292357 ENSG00000185010 ENSG00000143387 PMC11677171__F1 Effects of MSC-derived immunomodulatory and growth factors on survival, migration, phenotype and function of immune cells and parenchymal cells in inflamed and injured lacrimal and salivary glands ENSG00000178860 ENSG00000019991 ENSG00000002330 ENSG00000049768 PMC5843896__F7 Our working model ENSG00000168036 ENSG00000079999 PMC8099467__F4 Transcription factor networks of oligodendrogliomas treated with adjuvant radiotherapy or observation inform prognosis ENSG00000134086 ENSG00000132326 ENSG00000179094 ENSG00000060566 PMC8087671__F2 Proteomic and phosphoproteomic profiling of shammah induced signaling in oral keratinocytes ENSG00000110921 ENSG00000135218 ENSG00000115425 ENSG00000242110 ENSG00000110799 ENSG00000276559 ENSG00000148832 ENSG00000095321 ENSG00000158125 ENSG00000136457 ENSG00000107537 ENSG00000140876 ENSG00000152592 ENSG00000162928 ENSG00000034693 ENSG00000005469 ENSG00000121680 ENSG00000117305 ENSG00000142655 ENSG00000284807 ENSG00000176894 ENSG00000120915 ENSG00000018510 ENSG00000105516 ENSG00000124587 ENSG00000103150 ENSG00000288217 ENSG00000157911 ENSG00000150787 ENSG00000108733 ENSG00000112874 ENSG00000138759 ENSG00000164751 ENSG00000150893 ENSG00000164946 ENSG00000213965 ENSG00000026508 ENSG00000179761 ENSG00000101417 ENSG00000126432 PMC5159197__F1 IgA Nephropathy Enigma ENSG00000069482 ENSG00000079432 PMC1599906__F3 TGFB signaling pathway ENSG00000170365 ENSG00000137834 ENSG00000156574 PMC6097464__F5 Focal adhesion signaling highlighted in KEGG pathway analysis in parallel with SPIA pathway analysis by using microarray result of SNU-2335 set ENSG00000023445 ENSG00000112576 ENSG00000185634 ENSG00000002330 ENSG00000058085 ENSG00000077522 ENSG00000169032 ENSG00000164171 ENSG00000118971 ENSG00000197702 ENSG00000089159 ENSG00000137801 ENSG00000170962 ENSG00000010810 ENSG00000171914 ENSG00000160293 ENSG00000146648 PMC11062983__F7 pDNA-tachyplesin treatment stimulates the immune system and increases the probability of apoptosis in MC4-L2 tumor cells ENSG00000168610 PMC6097464__F7 TGF-beta signaling highlighted in KEGG pathway analysis in parallel with SPIA pathway analysis by using microarray result of SNU-2335 set ENSG00000049323 ENSG00000095739 ENSG00000198742 ENSG00000183691 ENSG00000134363 ENSG00000133740 ENSG00000204217 ENSG00000137801 PMC8313741__AF1 miR-301 regulates the SIRT1/SOX2 pathway via CPEB1 in the breast cancer progression ENSG00000096717 PMC6097464__F6 MAPK signaling highlighted in KEGG pathway analysis in parallel with SPIA pathway analysis by using microarray result of SNU-2335 set ENSG00000104856 ENSG00000066468 ENSG00000105329 ENSG00000075461 ENSG00000143507 ENSG00000078579 ENSG00000111837 ENSG00000269335 ENSG00000146648 ENSG00000081189 ENSG00000126458 PMC6097464__F9 Focal adhesion signaling highlighted in KEGG pathway analysis in parallel with SPIA pathway analysis by using microarray result of SNU-2414 set ENSG00000053747 ENSG00000226275 ENSG00000095739 ENSG00000058085 ENSG00000203618 ENSG00000134363 ENSG00000137801 PMC6097464__F8 TGF-beta adhesion signaling highlighted in KEGG pathway analysis in parallel with SPIA pathway analysis by using microarray result of SNU-2404 set ENSG00000168028 ENSG00000065613 ENSG00000128951 ENSG00000111837 ENSG00000100485 ENSG00000026103 PMC4935144__F1 Mammalian or mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway ENSG00000101407 ENSG00000106070 ENSG00000169047 ENSG00000198793 ENSG00000155792 PMC7367634__F1 MAPK and PI3K‐AKT‐mTOR signaling pathways ENSG00000157764 ENSG00000198793 ENSG00000163453 PMC8455332__F1 Suppressive actions of regulatory T cells ENSG00000134982 ENSG00000163599 PMC4015186__F1 MiRNA Regulation of the Human Glycome ENSG00000101901 ENSG00000172269 ENSG00000033011 ENSG00000128268 ENSG00000253710 ENSG00000168282 ENSG00000090581 ENSG00000139133 ENSG00000103174 ENSG00000088035 ENSG00000214160 ENSG00000177239 ENSG00000130175 ENSG00000111670 ENSG00000182050 ENSG00000089597 PMC7907026__F2 Diverse roles of the immune checkpoint in tumor cells that drive to the stimulation or inhibition of metastasis ENSG00000198793 ENSG00000168610 ENSG00000146648 ENSG00000007171 PMC4015186__F4 Insights into MiRNA Regulation of the Human Glycome ENSG00000281879 PMC4556941__F2 Key mechanisms regulating vascular smooth muscle tone ENSG00000173786 ENSG00000043591 PMC11481580__F7 Transcriptome sequencing analysis of overexpressed SikCDPK1 in tobacco reveals mechanisms of cold stress response ENSG00000111837 ENSG00000136997 ENSG00000011143 ENSG00000132341 PMC6249818__F6 Therapeutic targeting of the FOXM1 genetic network in myeloma ENSG00000117650 ENSG00000135446 PMC8173054__F1 Endocannabinoids and Precision Medicine for Mood Disorders and Suicide ENSG00000275723 ENSG00000117480 ENSG00000196689 ENSG00000147262 PMC7288916__F8 H19 in regulating dopaminergic neuron loss in PD ENSG00000107859 ENSG00000168036 PMC9095977__F3 Complement System and Alarmin HMGB1 Crosstalk: For Better or Worse ENSG00000107562 ENSG00000189403 ENSG00000121966 PMC4409212__F1 Novel Cancer Chemotherapy Hits by Molecular Topology: Dual Akt and Beta-Catenin Inhibitors ENSG00000002330 ENSG00000070831 ENSG00000198793 ENSG00000164327 PMC7140443__F1 Off state (left): In the absence of Sonic Hedgehog (SHH) ligand, Ptch inhibits signal transduction by SMO ENSG00000136997 ENSG00000164690 ENSG00000128602 PMC7140443__F4 Role of SHH/Gli cascade in Ewing sarcoma development ENSG00000151702 ENSG00000164690 ENSG00000128602 PMC4800317__F6 Non-canonical or alternative NFKB pathway ENSG00000104856 ENSG00000111321 ENSG00000131323 ENSG00000127191 PMC4800317__F5 Canonical or classical NFKB pathway ENSG00000144895 ENSG00000102871 ENSG00000186716 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC5889982__F1 Beta-arr is a potential therapeutic target for various diseases ENSG00000107562 ENSG00000198793 ENSG00000168036 ENSG00000167965 ENSG00000146648 ENSG00000121966 PMC5473974__F2 The glucocorticoid receptor and nitric oxide signaling pathways PMC6721829__F2 Role of miRNA-Regulated Cancer Stem Cells in the Pathogenesis of Human Malignancies ENSG00000198793 ENSG00000168610 PMC11652206__F2 Mechanisms by which phthalates affected sex steroids-related pathways ENSG00000070193 ENSG00000073060 ENSG00000105516 ENSG00000277893 ENSG00000164690 PMC6331208__F1 Neuroprotective effects of DBS at the synapse ENSG00000112561 ENSG00000164305 PMC6721829__F3 Role of miRNA-Regulated Cancer Stem Cells in the Pathogenesis of Human Malignancies ENSG00000168036 ENSG00000171791 ENSG00000168610 PMC11652206__F4 Mechanisms by which phthalates affected autophagy ENSG00000164161 ENSG00000105516 ENSG00000198793 PMC3742248__F2 Role of miR-302 during human ESCs (hESC) neural differentiation ENSG00000071564 ENSG00000143768 ENSG00000243709 ENSG00000156574 PMC11652206__F3 Mechanisms by which phthalates affect epithelial-mesenchymal transition (EMT) ENSG00000070087 ENSG00000105516 ENSG00000170558 ENSG00000067900 PMC5209621__F7 Classic mechanism for E2 action is E2 diffusing into the nucleus, binding to the nucleus estrogen receptor (ER), combining with ERE on DNA, starting transcription translation and inducing the cycle of multiplication in cancer cells ENSG00000198793 ENSG00000185591 PMC11652206__F7 Hypothesized macro-mechanism by which phthalates induce hypospadias ENSG00000277893 ENSG00000112715 ENSG00000168610 PMC8869699__F3 TLR2 in Infectious Diseases Caused by Mycobacteria: From Cell Biology to Therapeutic Target ENSG00000174125 ENSG00000170458 ENSG00000172005 ENSG00000160703 ENSG00000172936 ENSG00000083799 ENSG00000291918 ENSG00000162772 ENSG00000150455 ENSG00000175104 PMC8699626__F2 Hippo Signaling Pathway in Cancer: A Cell Cycle Perspective ENSG00000129474 ENSG00000186575 ENSG00000135446 ENSG00000123374 ENSG00000112118 ENSG00000105810 ENSG00000073111 ENSG00000150457 ENSG00000166851 ENSG00000076003 ENSG00000131023 ENSG00000166508 PMC8699626__F1 Hippo Signaling Pathway in Cancer: A Cell Cycle Perspective ENSG00000129474 ENSG00000186575 ENSG00000073910 ENSG00000150457 PMC7808154__F2 Interleukin‐17 and ischaemic stroke ENSG00000082512 ENSG00000157625 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000174611 ENSG00000076604 PMC10916417__F6 Relationship between PS, PC, and PE in the glycerophospholipid metabolic pathway ENSG00000185813 ENSG00000174915 ENSG00000173599 ENSG00000173868 ENSG00000156471 ENSG00000241878 PMC8693975__F1 Modeling and analysis of the macronutrient signaling network in budding yeast ENSG00000144895 PMC9354686__F6 Oncogenic Role of miR-217 During Clear Cell Renal Carcinoma Progression ENSG00000073792 ENSG00000165238 PMC9670321__F2 GNAQ mutations drive port wine birthmark-associated Sturge-Weber syndrome: A review of pathobiology, therapies, and current models ENSG00000038382 ENSG00000126016 ENSG00000198793 ENSG00000163914 PMC9104338__F9 In Vitro Effects of Papaverine on Cell Migration and Vascular Endothelial Growth Factor in Cancer Cell Lines ENSG00000198793 ENSG00000189403 ENSG00000171791 PMC8548662__F3 Roles of Exosomes as Future Therapeutic Agents and Diagnostic Tools for Glioma ENSG00000148400 PMC4167215__F1 The mitochondrial unfolded protein response in mammalian physiology ENSG00000144895 ENSG00000196365 PMC3157194__F4 Interaction between MAPK signaling pathway–related genes and miRNAs ENSG00000087095 ENSG00000185652 ENSG00000146648 PMC4039991__F1 Upregulation of a Steroid Synthesis Pathway in Th2 Cells In Vitro(A) Schematic representation of integrated steroid biosynthesis pathway with abbreviated metabolites (black) and protein factors (blue) ENSG00000160752 ENSG00000110921 ENSG00000132196 ENSG00000112972 ENSG00000130164 ENSG00000116133 ENSG00000172893 ENSG00000149809 ENSG00000109929 ENSG00000113161 ENSG00000104549 ENSG00000167508 PMC5559108__F3 Subtyping Chronic Obstructive Pulmonary Disease Using Peripheral Blood Proteomics ENSG00000105329 ENSG00000163739 ENSG00000138798 ENSG00000166670 ENSG00000112715 ENSG00000064300 ENSG00000225950 ENSG00000185652 ENSG00000049130 ENSG00000132692 ENSG00000100985 ENSG00000118257 ENSG00000005381 ENSG00000171560 PMC5675652__F6 Differential regulation of mRNAs and lncRNAs related to lipid metabolism in two pig breeds ENSG00000135218 ENSG00000101255 ENSG00000122877 ENSG00000099194 ENSG00000136826 PMC6231613__F3 Novel protein signatures suggest progression to muscular invasiveness in bladder cancer ENSG00000137807 ENSG00000102034 ENSG00000134824 ENSG00000198793 ENSG00000102890 ENSG00000164327 ENSG00000158435 ENSG00000100219 ENSG00000111371 ENSG00000170367 ENSG00000203783 ENSG00000155850 PMC4084821__F3 Irinotecan Pathway, view of a model human liver cell showing blood, bile, and intestinal compartments, indicating tissue-specific involvement of genes in the irinotecan pathway ENSG00000172831 ENSG00000114200 ENSG00000134982 ENSG00000103222 ENSG00000118777 ENSG00000023839 ENSG00000262243 PMC5623821__F9 Self‐sustaining cancer cells in 3D ENSG00000167601 ENSG00000019991 ENSG00000153208 ENSG00000092445 ENSG00000291971 ENSG00000198793 ENSG00000146648 ENSG00000184500 PMC8267694__F1 Enigmatic Role of TP53 in Germ Cell Tumours: Are We Missing Something? ENSG00000002330 ENSG00000171791 ENSG00000026103 PMC9693344__F3 Anticarcinogenic Effects of Isothiocyanates on Hepatocellular Carcinoma ENSG00000168040 PMC9693344__F2 Anticarcinogenic Effects of Isothiocyanates on Hepatocellular Carcinoma ENSG00000181019 ENSG00000100387 ENSG00000079999 PMC9832176__F2 TGFB signaling in the placenta via miR-574–5p mediated SMAD2/4 regulation PMC8390275__F5 Sirtuin3 rs28365927 functional variant confers to the high risk of non-alcoholic fatty liver disease in Chinese Han population ENSG00000142082 PMC3519901__F7 Quantification of the Host Response Proteome after Mammalian Reovirus T1L Infection ENSG00000213928 ENSG00000250361 ENSG00000184995 ENSG00000137275 ENSG00000177606 ENSG00000168040 PMC11799081__F1 Apoptosis and Necroptosis ENSG00000278718 ENSG00000137275 ENSG00000168040 PMC8186445__F2 Astrocytes in the Neurorepair Process ENSG00000107859 ENSG00000134982 ENSG00000168036 PMC8912934__F3 Tinker, Tailor, Tumour Suppressor: The Many Functions of PRP4K ENSG00000198793 ENSG00000146648 PMC6876279__F1 The JAK-Stat signalling pathway ENSG00000111537 PMC11668132__F1 Quercetin on cancer cell growth and proliferation ENSG00000149311 ENSG00000134982 ENSG00000146648 PMC5817811__F2 HGF/c-MET signaling pathway ENSG00000019991 ENSG00000198793 ENSG00000168610 PMC11220218__F1 Metabolic reprogramming in thyroid cancer and therapeutic resistance ENSG00000284320 ENSG00000157764 ENSG00000198793 ENSG00000079432 PMC11668132__F2 Quercetin on cancer cellular biomolecules and functions ENSG00000149311 ENSG00000002330 ENSG00000198793 PMC11058799__F7 Gene network crosstalk between selected DEGs (TYK2, STAT1 and TLR7) created with NetworkAnalyst software [44] ENSG00000275214 ENSG00000105397 ENSG00000115415 PMC5420131__F1 Canonical Wnt/Beta-catenin pathway: “WNT ON state”: WNT proteins, by binding to frizzled receptors and the LRP co-receptor, act to suppress the activity of glycogen synthase kinase-3B (GSK-3B) ENSG00000183579 ENSG00000168036 ENSG00000167074 PMC4245912__F2 The secretory pathways used by NMDARs ENSG00000117245 ENSG00000147044 ENSG00000130294 PMC9682745__F3 Innate immunity, cytokine storm, and inflammatory cell death in COVID-19 ENSG00000124256 ENSG00000137275 ENSG00000115415 ENSG00000125347 PMC8036620__F4 Apoptotic pathways involved in CIAKI ENSG00000128272 ENSG00000102871 ENSG00000168040 PMC9510148__F2 Contribution of altered neuronal autophagy to neurodegeneration ENSG00000177169 ENSG00000123395 ENSG00000083290 ENSG00000198793 PMC5429338__F2 Main potential molecular mechanism of the antitumour effect of anthocyanins in vitro ENSG00000087245 ENSG00000291971 ENSG00000138798 ENSG00000132646 ENSG00000100985 ENSG00000168610 PMC3633842__F6 Decreased Pattern Recognition Receptor Signaling, Interferon-Signature, and Bactericidal/Permeability-Increasing Protein Gene Expression in Cord Blood of Term Low Birth Weight Human Newborns ENSG00000163435 ENSG00000171105 ENSG00000144895 ENSG00000095321 PMC3633842__F5 Decreased Pattern Recognition Receptor Signaling, Interferon-Signature, and Bactericidal/Permeability-Increasing Protein Gene Expression in Cord Blood of Term Low Birth Weight Human Newborns ENSG00000134321 ENSG00000117226 ENSG00000115415 ENSG00000157601 ENSG00000135114 ENSG00000185745 ENSG00000115267 ENSG00000160710 ENSG00000111331 ENSG00000276561 PMC3633842__F4 Decreased Pattern Recognition Receptor Signaling, Interferon-Signature, and Bactericidal/Permeability-Increasing Protein Gene Expression in Cord Blood of Term Low Birth Weight Human Newborns ENSG00000213928 ENSG00000105397 ENSG00000089127 ENSG00000115415 ENSG00000157601 ENSG00000185745 ENSG00000230034 PMC5420131__F3 Immune exclusion through Wnt/beta-catenin pathway: Activation of Wnt/beta-catenin pathway in tumor leads to noninflammatory milieu through multiple mechanisms ENSG00000125538 ENSG00000168036 ENSG00000162772 ENSG00000049768 ENSG00000277943 PMC3633842__F2 Decreased Pattern Recognition Receptor Signaling, Interferon-Signature, and Bactericidal/Permeability-Increasing Protein Gene Expression in Cord Blood of Term Low Birth Weight Human Newborns ENSG00000236637 ENSG00000187608 PMC5420131__F2 Therapeutic targets in Wnt/Beta-catenin pathway and developmental therapeutics ENSG00000102312 ENSG00000168036 ENSG00000167074 PMC5070917__F1 Bruton’s tyrosine kinase in autoimmunity and implications for therapy ENSG00000095585 ENSG00000197943 ENSG00000010671 PMC8154153__F6 Compartmentalized Proteomic Profiling Outlines the Crucial Role of the Classical Secretory Pathway during Recombinant Protein Production in Chinese Hamster Ovary Cells ENSG00000118508 ENSG00000175115 ENSG00000134287 ENSG00000092108 ENSG00000162300 ENSG00000181789 ENSG00000136874 PMC3946959__F1 Proposed signaling pathway for PCB detoxification in vivo ENSG00000140465 ENSG00000106546 ENSG00000105227 PMC5027289__F7 PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development ENSG00000162552 ENSG00000168066 ENSG00000185231 ENSG00000179142 ENSG00000164690 PMC8802865__F10 Allosteric inhibition reveals SHP2-mediated tumor immunosuppression in colon cancer by single-cell transcriptomics ENSG00000183735 ENSG00000164430 PMC3364135__F1 EpCAM and its potential role in tumor-initiating cells ENSG00000138795 ENSG00000119888 ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000288292 PMC11900955__F2 TBK1 in key mechanisms of inflammation-associated diseases ENSG00000183735 PMC4815185__F7 Visualization of all differentially expressed proteins mapped to the TCA cycle pathway in the development of RAW 264.7 cells into osteoclasts in low serum culture system ENSG00000163114 ENSG00000067992 ENSG00000073578 ENSG00000100412 ENSG00000117118 ENSG00000005882 ENSG00000105953 ENSG00000110435 ENSG00000146701 ENSG00000131828 ENSG00000101365 ENSG00000062485 PMC9386326__F8 Dysregulated glucuronic acid metabolism exacerbates hepatocellular carcinoma progression and metastasis through the TGFB signalling pathway ENSG00000109814 ENSG00000119314 ENSG00000079999 PMC11900955__F1 Different immune cells by TBK1 ENSG00000183735 ENSG00000164430 PMC6109055__F6 Model: SIRT6 levels regulate resistance or sensitivity to MAPKi ENSG00000115457 ENSG00000077463 ENSG00000140443 PMC8738926__F4 Starvation-induced negative energy balance on endoplasmic reticulum stress in the liver of cows ENSG00000161533 ENSG00000100219 PMC9502833__F2 Prospects and Challenges of Electrospun Cell and Drug Delivery Vehicles to Correct Urethral Stricture ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6040832__F2 Progranulin, lysosomal regulation and neurodegenerative disease ENSG00000173372 ENSG00000112561 PMC3131688__F1 Autophagy in immunity and inflammation ENSG00000107562 ENSG00000167207 ENSG00000198793 ENSG00000171791 ENSG00000175505 ENSG00000106100 ENSG00000168610 ENSG00000062716 ENSG00000112977 ENSG00000188554 ENSG00000144848 ENSG00000113520 ENSG00000117335 ENSG00000189403 ENSG00000172936 ENSG00000128342 ENSG00000123268 PMC4909416__F1 The CDC20-APC/SOX2 pathway in human GSCs ENSG00000134982 ENSG00000117399 PMC7823972__F2 MSC-exosomes are capable of protecting against radiation-induced damage to hematopoietic and nonhematopoietic systems ENSG00000178860 ENSG00000138798 PMC7957490__F1 Crosstalk between MSCs and immune cells in the initial phase of tissue injury ENSG00000178860 ENSG00000108691 ENSG00000081041 ENSG00000107562 PMC7116639__F5 Regulatory R-loops as effectors of gene expression and genome stability ENSG00000012048 ENSG00000175054 ENSG00000083093 ENSG00000051180 ENSG00000139618 PMC7059126__F1 Illuminating insights into opsin 3 function in the skin ENSG00000104321 ENSG00000173599 PMC12043700__F4 Main regulatory mechanism of irisin in osteoclasts ENSG00000170909 ENSG00000131196 PMC12043700__F3 The improvement of osteoblast activity by irisin ENSG00000128272 ENSG00000167941 ENSG00000198793 ENSG00000168036 PMC12043700__F6 Regulatory functions of irisin in osteoarthritis relief through modulation of chondrocyte metabolism ENSG00000162711 ENSG00000142082 ENSG00000115594 ENSG00000171109 PMC9490861__F3 Osteogenic differentiation of periodontal membrane stem cells in inflammatory environments ENSG00000174125 ENSG00000172936 ENSG00000136869 PMC9592761__F3 Neuroinflammation of microglia polarization in intracerebral hemorrhage and its potential targets for intervention ENSG00000198793 ENSG00000087085 ENSG00000057663 ENSG00000132170 PMC5602294__F1 Biosynthetic pathway of NAD+ production starting from Na ENSG00000172890 ENSG00000278488 ENSG00000173614 PMC12043700__F2 Irisin in the regulation of MSC proliferation and differentiation ENSG00000139219 ENSG00000245848 ENSG00000170365 ENSG00000125398 ENSG00000167941 ENSG00000157766 ENSG00000198793 ENSG00000120693 ENSG00000168036 ENSG00000145782 ENSG00000204217 ENSG00000057663 PMC4769825__F2 Schematic illustration of pathways associated with Nrf2 signal ENSG00000178573 ENSG00000079999 PMC6737584__F3 Phosphorylation of central carbon metabolic enzymes ENSG00000143252 PMC7890031__F2 IL-17A on osteoblasts ENSG00000125538 ENSG00000168610 PMC7890031__F1 IL-17A on osteoclasts ENSG00000131323 ENSG00000007171 PMC6276815__F3 Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience ENSG00000106852 ENSG00000186487 ENSG00000084093 ENSG00000107859 ENSG00000163497 ENSG00000176165 ENSG00000179348 ENSG00000139352 ENSG00000016082 PMC10298151__F7 Diagram showing the mechanisms involved in D2R Beta-arrestin-dependent pathway-mediated ERK activation ENSG00000291971 PMC9060145__F4 Preclinical assessment of dual CYP26[A1/B1] inhibitor, DX308, as an improved treatment for keratinization disorders ENSG00000115956 ENSG00000175567 ENSG00000115718 PMC9434538__F2 JMJD family proteins in cancer and inflammation ENSG00000065833 ENSG00000070495 ENSG00000137265 ENSG00000082212 PMC10040548__F6 Sirtuin-dependent metabolic and epigenetic regulation of macrophages during tuberculosis ENSG00000092621 ENSG00000146733 ENSG00000116984 PMC10040548__F5 Sirtuin-dependent metabolic and epigenetic regulation of macrophages during tuberculosis ENSG00000105835 ENSG00000122966 ENSG00000092621 ENSG00000172005 PMC5508010__F5 To Eat and to Be Eaten: Mutual Metabolic Adaptations of Immune Cells and Intracellular Bacterial Pathogens upon Infection ENSG00000136997 ENSG00000078237 PMC8295685__F1 Sonic Hedgehog Pathway in the Development of the Central Nervous System and Aging-Related Neurodegenerative Diseases ENSG00000106571 ENSG00000166813 ENSG00000164690 ENSG00000128602 PMC3060380__F1 Myostatin activity and muscle growth ENSG00000095587 ENSG00000168487 ENSG00000114739 PMC2857179__F1 Mechanisms and pathways targeted by mutations in MPN ENSG00000110395 ENSG00000117400 ENSG00000187266 ENSG00000196712 PMC7109607__F3 SOX2-expressing tumor cells as potential therapeutic targets ENSG00000134982 ENSG00000164690 PMC8351602__F1 Intrinsic and extrinsic apoptotic signaling pathways ENSG00000168040 PMC3868569__F1 TATN-1 Mutations Reveal a Novel Role for Tyrosine as a Metabolic Signal That Influences Developmental Decisions and Longevity in Caenorhabditis elegans PMC3154417__F2 mTOR signaling pathway ENSG00000198793 ENSG00000163914 PMC9489775__F5 Selected transcripts of developmental signaling pathway genes implicated in dorsoventral and/or anteroposterior patterning containing two or more RNA editing sites detected at their 3′-UTR region ENSG00000004975 ENSG00000118518 ENSG00000131899 ENSG00000138443 ENSG00000120875 ENSG00000169439 ENSG00000073712 ENSG00000120925 ENSG00000105486 ENSG00000163251 ENSG00000006712 ENSG00000110906 ENSG00000143322 ENSG00000114739 PMC4110478__F1 Hypoxia inducible factor and VEGF link the HIF/VHL and PI3K/Akt/mTOR signaling pathways ENSG00000134086 ENSG00000148926 PMC7347234__F7 System-wide biochemical analysis reveals ozonide antimalarials initially act by disrupting Plasmodium falciparum haemoglobin digestion ENSG00000173599 ENSG00000102967 PMC5508010__F4 Quiescent (A) and activated (B) metabolism in differentiated mammalian cells ENSG00000180210 ENSG00000157404 ENSG00000197713 ENSG00000122966 ENSG00000172005 ENSG00000105953 PMC2937518__F4 Overview of predicted carbohydrate uptake and metabolism systems in bifidobacteria ENSG00000069482 ENSG00000150787 ENSG00000135517 PMC5508010__F2 Schematic presentation of the basic catabolic and anabolic processes of a typical heterotrophic prokaryotic cell: glycolytic pathway (GL), pentose-phosphate pathway (PPP) with its oxidative and non-oxidative arms, and tricarboxylic acid cycle (TCA) ENSG00000197713 ENSG00000122966 ENSG00000172005 ENSG00000105953 ENSG00000062485 PMC8384663__F1 Multifactorial pathogenesis of psoriatic disease ENSG00000162594 ENSG00000096996 ENSG00000141527 ENSG00000138378 ENSG00000159216 ENSG00000105397 ENSG00000118503 ENSG00000167755 ENSG00000127948 ENSG00000115009 PMC9459018__F4 Metabolome and RNA-seq Analysis of Responses to Nitrogen Deprivation and Resupply in Tea Plant (Camellia sinensis) Roots ENSG00000172005 ENSG00000127948 PMC9609565__F7 Morinda officinalis Polysaccharides Ameliorates Bone Growth by Attenuating Oxidative Stress and Regulating the Gut Microbiota in Thiram-Induced Tibial Dyschondroplasia Chickens PMC11959002__F2 ncRNAs promote PCa metastasis through the PAM signaling pathway ENSG00000094804 ENSG00000158290 ENSG00000146648 ENSG00000115009 PMC7159845__F3 Cellular model of insulin and leptin signaling in Kiss1ARH neurons ENSG00000170498 ENSG00000072315 PMC9459018__F6 Metabolome and RNA-seq Analysis of Responses to Nitrogen Deprivation and Resupply in Tea Plant (Camellia sinensis) Roots ENSG00000157404 ENSG00000156110 ENSG00000173599 ENSG00000151360 ENSG00000119125 PMC11959002__F1 ncRNAs inhibit PCa metastasis through the PAM signaling pathway ENSG00000158290 ENSG00000033327 ENSG00000117650 ENSG00000065361 ENSG00000171940 ENSG00000104341 PMC3585121__F6 Plant-Symbiotic Fungi as Chemical Engineers: Multi-Genome Analysis of the Clavicipitaceae Reveals Dynamics of Alkaloid Loci ENSG00000213658 ENSG00000145321 PMC7147028__F8 Schematic diagram showing potential involvement of miR-761 inhibiting EMT in CRS mice through targeting LCN2 in the LCN2/Twist1 signaling pathway ENSG00000148346 ENSG00000122691 ENSG00000170558 PMC11959002__F4 ncRNAs inhibit PCa growth through the PAM signaling pathway ENSG00000158290 ENSG00000136826 ENSG00000164778 ENSG00000134313 PMC11959002__F3 ncRNAs promote PCa growth through the PAM signaling pathway ENSG00000146648 ENSG00000115009 PMC11959002__F6 ncRNAs regulate PCa tumor stemness through the PAM signaling pathway ENSG00000168283 ENSG00000077782 ENSG00000146648 ENSG00000136826 ENSG00000140443 PMC11959002__F5 ncRNAs regulate PCa angiogenesis through the PAM signaling pathway ENSG00000198793 ENSG00000164327 ENSG00000134313 PMC8190037__F3 Analysis of the role of PurA in the pathogenesis of Alzheimer's disease based on RNA-seq and ChIP-seq ENSG00000132906 ENSG00000291983 ENSG00000002330 ENSG00000120868 ENSG00000168040 ENSG00000119912 ENSG00000164305 PMC3462655__F2 The signaling pathways involved in T-cell activation ENSG00000213658 ENSG00000062524 PMC5427104__F1 Activation and evasion of lectin pathway (LP) of complement ENSG00000166278 ENSG00000236625 PMC11508835__F4 Amino acid pathway interaction with mTORC1 ENSG00000145604 ENSG00000168003 ENSG00000134248 ENSG00000177058 ENSG00000052795 ENSG00000274070 ENSG00000176641 ENSG00000239282 ENSG00000103257 ENSG00000285069 PMC4310328__F1 Schematic figure of the complement system ENSG00000039537 ENSG00000009724 ENSG00000113600 ENSG00000203710 ENSG00000166278 ENSG00000132693 PMC11508835__F3 AMPK signaling pathway ENSG00000082146 ENSG00000145979 PMC6599710__F2 Genomic correlates of response to immune checkpoint blockade ENSG00000159128 ENSG00000183496 ENSG00000115415 ENSG00000027697 ENSG00000273686 ENSG00000125347 PMC9578007__F5 Regulatory network and interplay of hepatokines, stellakines, myokines and adipokines in nonalcoholic fatty liver diseases and nonalcoholic steatohepatitis ENSG00000160097 ENSG00000105835 ENSG00000170509 ENSG00000113140 ENSG00000250722 ENSG00000134363 ENSG00000164136 ENSG00000104918 ENSG00000146648 ENSG00000275031 PMC11508835__F2 Insulin/PI3K/AKT signaling interactions with mTOR ENSG00000140992 ENSG00000106070 ENSG00000169047 ENSG00000145979 ENSG00000115904 ENSG00000213341 ENSG00000169032 PMC9578007__F4 Regulatory network and interplay of hepatokines, stellakines, myokines and adipokines in nonalcoholic fatty liver diseases and nonalcoholic steatohepatitis ENSG00000109819 ENSG00000129214 ENSG00000145826 ENSG00000169710 ENSG00000132170 PMC11508835__F1 mTOR signaling pathway ENSG00000082146 ENSG00000104365 ENSG00000107404 ENSG00000281324 ENSG00000162337 ENSG00000169047 ENSG00000155792 ENSG00000274070 ENSG00000285069 ENSG00000145604 ENSG00000106070 ENSG00000176641 ENSG00000239282 PMC9578007__F3 Regulatory network and interplay of hepatokines, stellakines, myokines and adipokines in nonalcoholic fatty liver diseases and nonalcoholic steatohepatitis ENSG00000109819 ENSG00000288174 ENSG00000145192 ENSG00000134363 ENSG00000136869 ENSG00000175567 ENSG00000146648 ENSG00000132170 PMC9578007__F2 Regulatory network and interplay of hepatokines, stellakines, myokines and adipokines in nonalcoholic fatty liver diseases and nonalcoholic steatohepatitis ENSG00000109819 ENSG00000138207 ENSG00000197635 ENSG00000288174 ENSG00000169710 ENSG00000136869 ENSG00000197442 ENSG00000173262 ENSG00000079435 ENSG00000112115 ENSG00000146648 ENSG00000132170 PMC8525330__F3 CREB1 coordinates transcriptional networks in DCs and CD4+ T cells which drive key immune effector functions ENSG00000051523 ENSG00000153898 ENSG00000109332 ENSG00000011600 ENSG00000156642 ENSG00000185658 ENSG00000127511 ENSG00000197442 ENSG00000205250 ENSG00000116830 ENSG00000124762 ENSG00000069275 ENSG00000069667 ENSG00000150782 ENSG00000183735 ENSG00000157500 ENSG00000121068 ENSG00000276051 ENSG00000162892 ENSG00000140464 ENSG00000162889 ENSG00000005339 ENSG00000091972 ENSG00000197471 ENSG00000162520 ENSG00000129691 ENSG00000213341 ENSG00000231925 ENSG00000106100 ENSG00000273936 ENSG00000284984 ENSG00000132170 ENSG00000080802 ENSG00000169245 ENSG00000127445 ENSG00000100280 ENSG00000120899 ENSG00000102034 ENSG00000198517 ENSG00000122705 ENSG00000126353 ENSG00000135018 ENSG00000107874 PMC5889818__F3 Schematic overview of three different modes of cell death: apoptosis, necrosis and necroptosis ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC3745930__F5 Roles of hnRNPs in the impaired granulocytic differentiation of BCR/ABL transformed myeloid progenitor cells ENSG00000186716 PMC3577828__F6 Jejunal Proteins Secreted by db/db Mice or Insulin-Resistant Humans Impair the Insulin Signaling and Determine Insulin Resistance ENSG00000169047 PMC4863733__F2 Birth of a Carcinoma-associated fibroblasts ENSG00000081041 ENSG00000135218 ENSG00000162493 ENSG00000113140 ENSG00000134853 ENSG00000103241 ENSG00000164690 ENSG00000078098 PMC4267804__F6 RNA-Seq Analysis of Equine Conceptus Transcripts during Embryo Fixation and Capsule Disappearance ENSG00000132906 ENSG00000002330 ENSG00000291971 ENSG00000122194 PMC10526236__F4 MicroRNAs in the Regulation of RIG-I-like Receptor Signaling Pathway: Possible Strategy for Viral Infection and Cancer ENSG00000088888 ENSG00000164068 ENSG00000175104 ENSG00000121060 ENSG00000276561 PMC5838471__F1 Metabolic pathway of AB and GPCRs in Alzheimer's disease ENSG00000142192 ENSG00000002330 ENSG00000105723 PMC11506742__F1 TLR/IL-1R signaling pathway ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000168610 ENSG00000184216 PMC11506742__F2 IRAK1 in the metastatic cascade ENSG00000163739 ENSG00000170558 ENSG00000073111 ENSG00000162692 ENSG00000184216 ENSG00000115009 ENSG00000093009 PMC7432832__F1 Aryl hydrocarbon receptor (AhR) pathway ENSG00000106546 PMC7432832__F3 AhR pathway interactions in cancer breast cells ENSG00000136997 ENSG00000106546 PMC6280631__F2 The melanogenesis pathway shows where common ENAMs affect the pathway ENSG00000132464 ENSG00000157764 ENSG00000107165 PMC2537559__F5 Alterations in adhesion-mediated signaling and cytoskeleton remodeling in metastatic cancer ENSG00000038382 ENSG00000106682 ENSG00000011422 ENSG00000148204 ENSG00000112715 ENSG00000141968 ENSG00000104368 PMC2537559__F4 Alterations in extraceullular matrix and secreted proteins associated with metastatic cancer ENSG00000100234 ENSG00000011422 ENSG00000156103 ENSG00000138798 ENSG00000026508 ENSG00000166670 ENSG00000146648 ENSG00000122194 ENSG00000104368 ENSG00000135919 PMC2537559__F3 Glycolysis pathway ENSG00000074800 ENSG00000108515 ENSG00000164708 ENSG00000062485 PMC4995061__F1 Plasticity of Arterial and Venous Endothelial Cell Identity – Some Nerve! ENSG00000125266 ENSG00000196411 PMC6892980__F2 Macrophage exposure to Magnéli phases activates gene expression profiles associated with apoptosis and mitochondria dysfunction ENSG00000120868 ENSG00000083799 ENSG00000171791 ENSG00000057663 PMC4910072__F2 Respiratory metabolism and calorie restriction relieve persistent endoplasmic reticulum stress induced by calcium shortage in yeast ENSG00000167074 ENSG00000099194 ENSG00000123219 ENSG00000159399 PMC7322824__F1 STRING connectivity network analysis identified protein–protein interactions between CUL2, EGLN1, RBX1, LDHA, TFRC, and PFKL ENSG00000100387 PMC8945049__F4 Differential Transcriptome Profiling Unveils Novel Deregulated Gene Signatures Involved in Pathogenesis of Alzheimer’s Disease ENSG00000145864 ENSG00000135297 ENSG00000100413 ENSG00000070831 ENSG00000134982 ENSG00000117118 ENSG00000147133 ENSG00000254999 ENSG00000038002 ENSG00000089159 ENSG00000169231 ENSG00000004487 ENSG00000166501 ENSG00000135932 ENSG00000071051 ENSG00000089169 ENSG00000114125 ENSG00000143549 ENSG00000147162 ENSG00000170027 ENSG00000140795 ENSG00000117152 ENSG00000042753 ENSG00000143933 ENSG00000184787 ENSG00000102003 ENSG00000143252 ENSG00000173805 ENSG00000125675 ENSG00000147669 ENSG00000135407 ENSG00000128285 PMC11033503__F1 C/EBPB regulates signaling pathways associated with brain inflammation in AD ENSG00000168398 ENSG00000163606 PMC4023866__F1 Bacterial effectors that target and manipulate the innate immune and inflammatory pathways ENSG00000166855 ENSG00000170458 ENSG00000136869 ENSG00000175104 PMC11851453__F1 Two-end black (TEB) coat color phenotype, schematic diagram of EDNRB transcripts and their encoded protein, three-dimensional structure prediction of the EDNRB protein, and an EDNRB melanin pathway diagram ENSG00000136160 PMC11033503__F2 C/EBPB: A transcription factor associated with the irreversible progression of Alzheimer's disease ENSG00000142192 ENSG00000135250 PMC11033503__F4 C/EBPB: A transcription factor associated with the irreversible progression of Alzheimer's disease ENSG00000144935 ENSG00000167323 ENSG00000293604 PMC4300719__F6 Pathway analysis in groups A (A) and B (B) ENSG00000068028 ENSG00000132906 ENSG00000189283 ENSG00000033327 ENSG00000002330 PMC6057902__F2 Extended, context‐specific melatonin receptor signalling pathways ENSG00000150907 ENSG00000171791 ENSG00000096717 ENSG00000142082 PMC2934775__F9 Fluxmap of the glycolysis, penthose phosphate pathway, and citric acid cycle for the experiment where nitrogen-limiting medium is changed to carbon-limiting medium at time zero ENSG00000122966 ENSG00000172005 ENSG00000150787 PMC2934775__F8 Fluxmap of the glycolysis, penthose phosphate pathway, and citric acid cycle for the experiment where carbon-limiting medium is changed to nitrogen-limiting medium at time zero ENSG00000122966 ENSG00000172005 ENSG00000150787 PMC8530873__F1A Stress stimulus produces a physiological response which involves the central nervous system (CNS) and the periphery ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000142178 ENSG00000160584 ENSG00000170145 ENSG00000051180 PMC3038194__F1 Therapeutic strategies and mechanisms of tumorigenesis of HER2-overexpressing breast cancer ENSG00000002330 ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000158458 ENSG00000146648 PMC2515336__F2 Representation of the two NFKB signaling pathways ENSG00000104856 ENSG00000173039 PMC2709856__F1 It’s all in the family: multiple Toll-like receptors offer promise as novel therapeutic targets for stroke neuroprotection ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC5859251__F6 TRIM29 regulating anti-DNA virus immune response through targeting STING ENSG00000183735 ENSG00000164430 ENSG00000137699 PMC2707763__F6 PROK1 induction of RCAN1-4 and IL-8 ENSG00000169618 ENSG00000159200 ENSG00000164879 ENSG00000166278 ENSG00000117602 ENSG00000143125 PMC2268661__F2 The diagram of GSH redox cycle ENSG00000167468 ENSG00000023909 PMC8245224__F9 Loss of Function of von Hippel-Lindau Trigger Lipocalin 2-Dependent Inflammatory Responses in Cultured and Primary Renal Tubular Cells ENSG00000148346 ENSG00000134086 ENSG00000159399 PMC6366148__F3 PI3K/Akt/mTOR pathway activated by IL-2 and CD28 signaling and growth factors ENSG00000198793 ENSG00000168685 PMC5833125__F2 Signaling networks in osteoclastogenesis ENSG00000095585 ENSG00000170909 ENSG00000033327 ENSG00000134215 ENSG00000175104 ENSG00000127191 ENSG00000131196 ENSG00000135605 ENSG00000010671 PMC7520308__F1 Biosynthetic pathway of tetrahydrobiopterin: de novo pathway from GTP and two other salvage pathways from sepiapterin and 1′‐hydroxy‐2′‐oxopropyl‐tetrahydropterin, respectively ENSG00000228716 ENSG00000116096 PMC2875112__F1A Targeting Multiple Kinase Pathways. A Change In Paradigm ENSG00000002330 PMC8394096__F1 Pathogenic Role of PI3K/AKT Pathway in Cancer Onset and Drug Resistance: An Updated Review ENSG00000002330 ENSG00000149269 PMC10750291__F4 Biological mechanism and emerging therapeutic interventions of liver aging ENSG00000087095 ENSG00000102871 PMC3146512__F2 Genome Sequence of a Mesophilic Hydrogenotrophic Methanogen Methanocella paludicola, the First Cultivated Representative of the Order Methanocellales ENSG00000127948 PMC10750291__F6 Biological mechanism and emerging therapeutic interventions of liver aging ENSG00000148346 ENSG00000171320 ENSG00000108055 ENSG00000134982 ENSG00000102871 ENSG00000163220 ENSG00000205250 ENSG00000277273 ENSG00000168040 ENSG00000143556 ENSG00000129933 ENSG00000117399 ENSG00000140534 ENSG00000141446 ENSG00000145604 ENSG00000094804 ENSG00000172167 ENSG00000135446 ENSG00000132646 ENSG00000136997 ENSG00000123374 ENSG00000164754 ENSG00000105810 ENSG00000071539 PMC1681468__F6 Combinations of multiple states of complexes ENSG00000065361 ENSG00000158458 PMC10750291__F5 Biological mechanism and emerging therapeutic interventions of liver aging ENSG00000110711 ENSG00000239732 ENSG00000128272 ENSG00000170458 ENSG00000172936 ENSG00000131323 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000084774 ENSG00000143387 PMC1681468__F5 Ellipsis in drawing association states of proteins using an 'address' ENSG00000169291 ENSG00000138798 ENSG00000146648 PMC4140976__F2 Tissue-specific Insulin Signaling in the Regulation of Metabolism and Aging ENSG00000169047 ENSG00000140443 PMC4140976__F1 Tissue-specific Insulin Signaling in the Regulation of Metabolism and Aging ENSG00000177169 ENSG00000157500 ENSG00000002330 ENSG00000106070 ENSG00000198793 PMC7366241__F1 Non-coding RNA in GC ENSG00000143222 ENSG00000145321 ENSG00000168036 ENSG00000187772 ENSG00000140807 PMC8465902__F5 Iron–Sulfur Cluster Biogenesis as a Critical Target in Cancer ENSG00000182511 ENSG00000116688 PMC8465902__F4 Iron–Sulfur Cluster Biogenesis as a Critical Target in Cancer ENSG00000005194 ENSG00000103274 ENSG00000124479 ENSG00000155229 ENSG00000103245 ENSG00000144021 ENSG00000122873 ENSG00000188566 ENSG00000145354 ENSG00000166595 PMC1992519__F2 Signaling on the endocytic pathway ENSG00000102189 ENSG00000138798 ENSG00000146648 PMC6941297__F1 Protein expression, molecular pahtways, facilitators and mutations involved in the genesis of brain metastases from melanoma, breast and lung cancer ENSG00000169594 ENSG00000107562 ENSG00000157764 ENSG00000288490 ENSG00000163131 ENSG00000198793 ENSG00000163914 ENSG00000131747 ENSG00000146648 ENSG00000121966 ENSG00000079999 PMC4186342__F1 Trafficking of TLR4 ENSG00000134970 ENSG00000170458 ENSG00000103769 ENSG00000136869 ENSG00000084733 ENSG00000276600 PMC5839936__F2 Proteins significantly altered by torcetrapib associated with aldosterone synthesis or function ENSG00000105329 ENSG00000146469 ENSG00000050165 ENSG00000115138 ENSG00000091879 ENSG00000131096 ENSG00000120937 PMC10779133__F2 Neuroprotective effects of KBs and KD by providing energy source and improving mitochondrial dysfunction in the brain ENSG00000150907 ENSG00000096717 ENSG00000142082 ENSG00000283100 PMC10779133__F1 Ketogenic and ketolytic pathways in the liver and brain cells ENSG00000075239 ENSG00000275544 ENSG00000062485 ENSG00000117305 PMC10779133__F4 Signaling functions of KBs and KD for anti-neuroinflammation and autophagic flux ENSG00000177169 ENSG00000162711 ENSG00000150907 ENSG00000163914 ENSG00000005893 ENSG00000112561 ENSG00000168610 PMC5839936__F3 Proteins significantly altered by torcetrapib associated with insulin sensitivity or pancreatic Beta-cell function ENSG00000087245 ENSG00000135218 ENSG00000065675 ENSG00000112964 ENSG00000105329 ENSG00000070404 ENSG00000105723 PMC10779133__F3 Signaling functions of KBs and KD for anti-apoptosis, antioxidant defense, and epigenetic and post-translational modifications ENSG00000150907 ENSG00000086991 ENSG00000175567 PMC4286324__F3 Schematic diagram describing Src regulation by trafficking ENSG00000143878 ENSG00000291971 PMC11846620__F6 Molecular Mechanisms of Immunoinflammatory Infiltration and Ferroptosis in Arthritis Revealed by a Combination of Bioinformatics and Single-Cell Analysis ENSG00000180210 ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000181867 ENSG00000115107 ENSG00000057663 PMC2615463__F1 Arc function in mGluR-LTD ENSG00000284161 ENSG00000198576 ENSG00000167658 PMC3049852__F1 Multifunctional effects of CMKLR1 activation ENSG00000174600 ENSG00000291971 ENSG00000198793 PMC8929637__F2 An illustration of the known proteins involved in glycerolipid synthesis in Apicomplexa parasites ENSG00000011007 ENSG00000198670 ENSG00000154582 ENSG00000026103 PMC6292430__F2 Does Axl have potential as a therapeutic target in pancreatic cancer? ENSG00000167601 ENSG00000115415 ENSG00000146648 PMC10037252__F2 Systemic treatment for metastatic colorectal cancer ENSG00000169047 ENSG00000198793 ENSG00000146648 PMC2676302__F5 Major trends in mRNA expression at 56 days on experimental diets and summary network analysis among genes ENSG00000130304 ENSG00000131473 ENSG00000134824 ENSG00000151365 ENSG00000169710 ENSG00000099194 ENSG00000101577 ENSG00000132356 ENSG00000132170 PMC9138678__F1 Brain-Derived Neurotropic Factor in Neurodegenerative Disorders ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000172936 PMC8230033__F1 Altered Bone Status in Rett Syndrome ENSG00000281324 ENSG00000162337 ENSG00000134569 ENSG00000168036 ENSG00000106483 PMC4376959__F2 Sphingolipid metabolism ENSG00000139624 ENSG00000100422 ENSG00000063176 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000143418 PMC2817888__F3 ATM/ATR DNA damage response pathway and its downstream effectors leading to either G1/S or G2/M phase arrest ENSG00000149311 ENSG00000175054 ENSG00000123374 PMC4286324__F1 Membrane dynamics and the endocytic pathway ENSG00000013016 ENSG00000274145 PMC4484234__F1 Structures of schweinfurthin B and 3-deoxyschweinfurthin B (3dSB) ENSG00000160752 ENSG00000197429 PMC9793423__F1 Pleiotropic role, functions and targeted therapies of LIF/LIFR axis in cancer: Old spectacles with new insights ENSG00000099985 ENSG00000242689 ENSG00000128342 ENSG00000105205 PMC4888213__F3 Multiple somatic alterations in components within the same pathways ENSG00000149311 ENSG00000281614 ENSG00000134982 ENSG00000198793 ENSG00000155011 ENSG00000065559 ENSG00000139687 PMC3262546__F1 The p14-p53-p21 and p16-Rb signaling pathways involved in fibroblast senescence ENSG00000135446 ENSG00000123374 PMC9793423__F5 Pleiotropic role, functions and targeted therapies of LIF/LIFR axis in cancer: Old spectacles with new insights ENSG00000087245 ENSG00000168036 ENSG00000107485 ENSG00000128342 ENSG00000168610 ENSG00000125968 PMC2778684__F1 Canonical and non-canonical Wnt signaling pathways ENSG00000162337 ENSG00000100592 ENSG00000134982 PMC2915874__F4 Effect of estrogen on endothelium-dependent pathways of vascular relaxation ENSG00000291971 ENSG00000145321 PMC2915874__F3 ER-activated postreceptor mechanisms ENSG00000291971 ENSG00000113070 ENSG00000146648 PMC3516599__F1 Proposed Multicompartmental Degradative Pathway of L-lysineL-Lysine degradation is initiated by either peroxisomal Alpha-deamination (pipecolate pathway) or mitochondrial E-deamination (saccharopine pathway) ENSG00000157426 ENSG00000179761 ENSG00000105607 ENSG00000181192 PMC7518784__F2 Inflammatory induction of the colorectal cancer (CRC) occurrence ENSG00000163464 ENSG00000157764 ENSG00000112115 ENSG00000168610 PMC5682390__F1 Metabolic pathways for engineering oleaginous yeasts to produce a variety of different compounds ENSG00000168040 ENSG00000084774 ENSG00000026103 PMC4281941__F10 miR-93-directed down-regulation of DAB2 defines a novel oncogenic pathway in lung cancer ENSG00000117525 ENSG00000153094 ENSG00000291837 ENSG00000164938 ENSG00000150457 ENSG00000112715 ENSG00000124762 PMC2575183__F7 Proposed signaling mechanism that stimulates EMT ENSG00000138795 ENSG00000168036 PMC10558021__F2 Cyclophosphamide metabolic pathway ENSG00000165841 ENSG00000197408 PMC10095465__F1 Apoptotic signaling pathway ENSG00000002330 ENSG00000102871 ENSG00000168040 ENSG00000135116 ENSG00000104081 ENSG00000026103 PMC3093880__F8 miR-122 and liver-related functions and diseases ENSG00000104812 ENSG00000132612 ENSG00000139514 ENSG00000137673 ENSG00000114923 ENSG00000175220 ENSG00000196396 ENSG00000089159 ENSG00000113552 ENSG00000158825 ENSG00000047849 ENSG00000105552 ENSG00000062485 PMC9563233__F1 ITGB5 promotes innate radiation resistance in pancreatic adenocarcinoma by promoting DNA damage repair and the MEK/ERK signaling pathway ENSG00000188486 ENSG00000149311 ENSG00000183765 PMC8807479__F4 Functions and Regulation of Translation Elongation Factors ENSG00000148399 ENSG00000134146 ENSG00000182511 ENSG00000154813 ENSG00000167658 ENSG00000108963 PMC3093880__F9 Associations among miR-122-identified targets ENSG00000137673 ENSG00000059804 ENSG00000175220 ENSG00000175592 ENSG00000169032 ENSG00000087077 ENSG00000196396 ENSG00000089159 ENSG00000172216 ENSG00000177606 ENSG00000158825 ENSG00000220205 ENSG00000100941 ENSG00000111142 ENSG00000130669 ENSG00000127616 PMC6822533__F1 Engineering anti-cancer nanovaccine based on antigen cross-presentation ENSG00000265808 ENSG00000103769 PMC6207917__F6 Mechanism of DQP on cardiac lipid and glucose metabolism ENSG00000115361 PMC6053540__F4 Biogenesis of miR-451 ENSG00000145321 ENSG00000113360 ENSG00000123908 PMC5993488__F2B Cumulative HLA class I and APM defects across gliomas from TCGA ENSG00000232326 ENSG00000231925 ENSG00000125347 PMC3836075__F5 The role of Ang II and its metabolites in the adrenal gland vasculature ENSG00000130234 ENSG00000137509 PMC9325158__F1 Activation of Stimulation of Interferon Genes (STING) Signal and Cancer Immunotherapy ENSG00000104856 ENSG00000213928 ENSG00000164430 ENSG00000175104 ENSG00000142166 PMC10142234__F1 Graphical representation of JAK-STAT signaling pathway and therapeutic compounds suppressing it through the inhibition of one or several members of the family ENSG00000105397 ENSG00000105639 PMC2713566__F1 Mitochondrial pathways of electron flow resulting from the substrates and inhibitors used in this study ENSG00000182511 ENSG00000122966 ENSG00000172005 PMC8905312__F1 Candida albicans stress response pathways in antifungal tolerance and resistance ENSG00000196511 PMC6262299__F2 Neurotrophic factor (NTFs) signaling pathways ENSG00000002330 ENSG00000242689 PMC5891588__F1 Development of NEPC by the SRRM4-mediated RNA splicing network ENSG00000135365 ENSG00000129514 PMC8255319__F2 Molecular biology of pancreatic adenocarcinoma: translational challenges and clinical perspectives ENSG00000057252 ENSG00000131473 ENSG00000065833 ENSG00000197713 ENSG00000130164 ENSG00000198380 ENSG00000113161 ENSG00000169710 ENSG00000153574 ENSG00000103257 ENSG00000159399 PMC6146607__F1 Lipogenesis and cholesterol synthesis pathways ENSG00000131473 ENSG00000170522 ENSG00000169710 ENSG00000099194 ENSG00000075239 ENSG00000026103 PMC8198029__F4 SARS-CoV-2-Induced Gut Microbiome Dysbiosis: Implications for Colorectal Cancer ENSG00000143799 ENSG00000198793 ENSG00000150782 ENSG00000070444 ENSG00000239732 ENSG00000181847 ENSG00000113520 ENSG00000189403 ENSG00000136869 ENSG00000105246 ENSG00000174125 ENSG00000115008 ENSG00000154589 ENSG00000100906 ENSG00000109320 ENSG00000269335 ENSG00000173039 ENSG00000073756 ENSG00000168610 ENSG00000007171 ENSG00000132170 ENSG00000169245 ENSG00000111537 ENSG00000115415 ENSG00000164136 ENSG00000026508 ENSG00000126353 ENSG00000100985 ENSG00000112115 PMC8198029__F3 SARS-CoV-2-Induced Gut Microbiome Dysbiosis: Implications for Colorectal Cancer ENSG00000157764 ENSG00000291971 ENSG00000168036 ENSG00000112715 ENSG00000125347 ENSG00000168811 ENSG00000073756 ENSG00000168610 ENSG00000136826 ENSG00000069667 ENSG00000145839 ENSG00000125398 ENSG00000163558 ENSG00000125538 ENSG00000166501 ENSG00000026508 ENSG00000113520 ENSG00000189403 ENSG00000172936 ENSG00000112115 ENSG00000196689 ENSG00000140464 PMC7862565__F24 Molecular signaling pathway ENSG00000136997 ENSG00000136869 ENSG00000168040 PMC8198029__F1 SARS-CoV-2-Induced Gut Microbiome Dysbiosis: Implications for Colorectal Cancer ENSG00000165556 ENSG00000152661 ENSG00000119888 ENSG00000134982 ENSG00000138798 ENSG00000101843 ENSG00000141564 ENSG00000148344 ENSG00000162772 ENSG00000121879 ENSG00000137801 ENSG00000150782 ENSG00000176692 ENSG00000011422 ENSG00000168090 ENSG00000168214 ENSG00000115457 ENSG00000004487 ENSG00000113722 ENSG00000115548 ENSG00000148400 ENSG00000109321 ENSG00000116237 ENSG00000274205 ENSG00000071564 ENSG00000177189 ENSG00000111537 ENSG00000163235 ENSG00000124882 ENSG00000156427 ENSG00000073861 ENSG00000175792 PMC6335273__F4 Three main features (GSIS, beta cell mass and insulin action) and insulin secretion pathway in GK rat ENSG00000006071 ENSG00000102001 ENSG00000002330 ENSG00000183844 ENSG00000048052 ENSG00000235194 ENSG00000121853 ENSG00000119912 ENSG00000162104 PMC9650235__F3 IL-7: A promising adjuvant ensuring effective T cell responses and memory in combination with cancer vaccines? ENSG00000002330 ENSG00000150907 ENSG00000105639 PMC8839962__F1 Metabolic Features of Brain Function with Relevance to Clinical Features of Alzheimer and Parkinson Diseases ENSG00000082175 ENSG00000169047 ENSG00000198793 ENSG00000102104 PMC3794211__F2 MiRNAs implicated in neurodegeneration ENSG00000084093 ENSG00000142192 ENSG00000197386 ENSG00000137845 PMC7369905__F4 NRF2 regulates inflammation and immunity PMC7369905__F3 NRF2 regulates metabolism ENSG00000180210 ENSG00000065833 ENSG00000065911 ENSG00000135423 ENSG00000074800 ENSG00000151012 ENSG00000188316 ENSG00000149485 ENSG00000124253 ENSG00000166123 ENSG00000023909 PMC8462294__F2 Progression on the Roles and Mechanisms of Tumor-Infiltrating T Lymphocytes in Patients With Hepatocellular Carcinoma ENSG00000168036 ENSG00000049768 ENSG00000168610 PMC4986688__F1A Immune mediators of chronic pelvic pain syndrome ENSG00000184995 ENSG00000113520 PMC2689776__F7 Proteomics and Pathway Analysis Identifies JNK Signaling as Critical for High Linear Energy Transfer Radiation-induced Apoptosis in Non-small Lung Cancer Cells ENSG00000140443 ENSG00000026103 PMC4654485__F2 Computational Model of MicroRNA Control of HIF-VEGF Pathway: Insights into the Pathophysiology of Ischemic Vascular Disease and Cancer ENSG00000134086 ENSG00000138823 ENSG00000092847 ENSG00000112715 ENSG00000166135 PMC3821857__F7 DOK2 Inhibits EGFR-Mutated Lung Adenocarcinoma ENSG00000138798 ENSG00000146648 PMC5569050__F5 Mechanism of skin dopaminergic sensory modulation ENSG00000154864 ENSG00000123454 ENSG00000196689 PMC8149214__F5 Epidermal Growth Factor Protects Against High Glucose-Induced Podocyte Injury Possibly via Modulation of Autophagy and PI3K/AKT/mTOR Signaling Pathway Through DNA Methylation ENSG00000181104 ENSG00000198793 PMC6522820__F2 Effect of the PI3K/AKT signaling pathway on gynecological tumors PMC6522820__F1 The PI3K/AKT signaling pathway ENSG00000138798 PMC2769250__F3A Trafficking of Heme and Porphyrins in Metazoa ENSG00000080819 ENSG00000126088 ENSG00000188690 ENSG00000115657 PMC11528219__F2 Stomatal development by environmental signaling in Arabidopsis ENSG00000105722 ENSG00000164151 ENSG00000167434 PMC8492792__F4 Multiple strategies for inhibiting Hh signal transduction pathway ENSG00000141867 ENSG00000128602 PMC2829367__F1 Selective matrix metalloproteinase (MMP) inhibitors in cancer therapy ENSG00000138795 ENSG00000122691 ENSG00000026508 ENSG00000168036 PMC8492792__F3 Hh signaling in cancer ENSG00000143147 ENSG00000128602 PMC8492792__F1 Conserved Hh signal transduction pathway ENSG00000166813 ENSG00000121067 ENSG00000128602 PMC7857091__F1 Deciphering the Intricate Roles of Radiation Therapy and Complement Activation in Cancer ENSG00000039537 ENSG00000009724 ENSG00000113600 ENSG00000120054 ENSG00000203710 ENSG00000196352 ENSG00000166278 PMC8616011__F3 Immunotherapy in Breast Cancer: When, How, and What Challenges? ENSG00000108691 ENSG00000273686 PMC7758290__F1 Complement system ENSG00000203710 ENSG00000196352 ENSG00000117335 ENSG00000120885 ENSG00000166278 ENSG00000182326 PMC3828559__F1 RAS-RAF pathway and immunohistochemical staining of colorectal cancer specimens with BRAF V600E mutation specific monoclonal antibody ENSG00000157764 ENSG00000146648 PMC5260505__F6 Proposed function of CDK1 in regulating pluripotency PMC5362072__F3 Cell-intrinsic effect of STING activation in tumor cellsThe functionality of the STING signaling pathway can be altered in tumors.A) Oncolytic viruses like HPV or adenoviruses drive E7 or E1A oncoprotein expression ENSG00000164430 ENSG00000101146 PMC4831676__F7 Hypoxia Induces Autophagy through Translational Up-Regulation of Lysosomal Proteins in Human Colon Cancer Cells ENSG00000177169 ENSG00000128272 ENSG00000144895 ENSG00000136643 ENSG00000198793 ENSG00000243056 ENSG00000162302 PMC4370290__F3 Pathways involved to block cell cycle progression ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000101224 PMC2827616__F8 Signaling pathways controlling ENS precursor migration and lamellipodia formation ENSG00000169291 ENSG00000070831 ENSG00000163914 PMC4819324__F1 Targeting geranylgeranylation reduces adrenal gland tumor burden in a murine model of prostate cancer metastasis ENSG00000160752 ENSG00000197429 PMC9441940__F1 Multiple myeloma metabolism – a treasure trove of therapeutic targets? ENSG00000115902 ENSG00000092621 PMC11985624__F2 Conceptual representation of potential mechanisms for osteogenic effects of exercise ENSG00000178860 ENSG00000167941 ENSG00000154059 PMC8093649__F6 Nuclear Factor Kappa B (NF-kB) signaling in cancer development and immune diseases ENSG00000127191 PMC7313746__F4 Signature genes associated with immunological non-responsiveness to anti-retroviral therapy in HIV-1 subtype-c infection ENSG00000198918 ENSG00000182568 ENSG00000150093 ENSG00000138326 ENSG00000091409 ENSG00000177733 ENSG00000174444 ENSG00000123219 ENSG00000111602 ENSG00000004700 ENSG00000150991 ENSG00000134419 ENSG00000115232 PMC11985624__F1 Osteocytic changes in sclerostin expression mediate bone mechanotransduction to skeletal loading ENSG00000178860 ENSG00000134982 ENSG00000168036 PMC8093649__F3 Nuclear Factor Kappa B (NF-kB) signaling in cancer development and immune diseases ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 PMC7353046__F7 Adams–Oliver Syndrome and Notch signaling ENSG00000168214 ENSG00000130158 ENSG00000128917 PMC7353046__F6 Dowling Degos Diseases and Notch signaling ENSG00000186081 ENSG00000205155 ENSG00000101346 PMC8615798__F6 Association of Mutations Identified in Xanthinuria with the Function and Inhibition Mechanism of Xanthine Oxidoreductase ENSG00000124217 ENSG00000164172 ENSG00000171723 ENSG00000124615 ENSG00000075643 PMC8093260__F1 An update on the regulatory mechanisms of NLRP3 inflammasome activation ENSG00000162711 ENSG00000124256 ENSG00000135218 ENSG00000137275 ENSG00000265972 ENSG00000168040 ENSG00000036828 ENSG00000267534 ENSG00000141867 ENSG00000088888 ENSG00000134830 ENSG00000116688 ENSG00000010810 ENSG00000125538 ENSG00000136869 ENSG00000172936 ENSG00000168404 ENSG00000175104 ENSG00000285379 ENSG00000164342 PMC12123091__F4 Key metabolic pathways of proline and hydroxyproline in the cell ENSG00000125246 ENSG00000100033 PMC12123091__F3 Metabolic pathway of hydroxyproline as an initial product for intracellular interconversions and processes ENSG00000250799 ENSG00000100033 ENSG00000167701 PMC7246457__F5 Network analysis of proteins related to inflammation-driven pathology of ARPE-19 cells ENSG00000284774 ENSG00000166086 ENSG00000291971 ENSG00000115904 ENSG00000168036 ENSG00000168040 ENSG00000023909 ENSG00000102879 ENSG00000162409 ENSG00000153395 ENSG00000099810 ENSG00000185591 ENSG00000124181 ENSG00000186174 ENSG00000146648 ENSG00000115419 ENSG00000116761 ENSG00000127948 ENSG00000127616 ENSG00000026103 PMC5749905__F1 mTOR signaling pathway and its upstream elements ENSG00000164362 ENSG00000196712 PMC4900950__F3 Signaling pathways regulating Müller glia cell dedifferentiation and proliferation following retinal injury in zebrafish ENSG00000177426 ENSG00000173404 ENSG00000113070 ENSG00000168036 ENSG00000168610 ENSG00000139352 PMC3982454__F8 CD44 protein-protein interaction pathways were performed by String 9.0 Web software ENSG00000150991 ENSG00000150907 ENSG00000198793 ENSG00000164362 ENSG00000026508 ENSG00000159335 PMC2577715__F9 Nrf2 and transcriptional regulation of Gamma-GCSh expression ENSG00000198517 ENSG00000079999 PMC9524569__F2 Protective role of ethyl pyruvate in spinal cord injury by inhibiting the high mobility group box-1/toll-like receptor4/nuclear factor-kappa B signaling pathway ENSG00000162711 ENSG00000173039 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC2577715__F4 NFKB signaling and MDR gene expression ENSG00000104856 ENSG00000172936 PMC9695095__F2 The NLRP3 inflammasome in chronic inflammation in asthma and chronic obstructive pulmonary disease ENSG00000278718 ENSG00000162711 ENSG00000291363 ENSG00000104321 ENSG00000160710 ENSG00000136869 ENSG00000087842 ENSG00000096717 ENSG00000196689 ENSG00000106546 PMC3525581__F7 Toxicogenomic Analysis Suggests Chemical-Induced Sexual Dimorphism in the Expression of Metabolic Genes in Zebrafish Liver PMC6025455__F4 Endothelial targeting to boost endogenous antithrombotic and anti-inflammatory pathways ENSG00000134982 ENSG00000173599 PMC8842666__F6 ASB17 Facilitates the Burst of LPS-Induced Inflammation Through Maintaining TRAF6 Stability ENSG00000154007 ENSG00000173039 ENSG00000175104 PMC9139376__F6 Three-Dimensional Organotypic Cultures Reshape the microRNAs Transcriptional Program in Breast Cancer Cells ENSG00000138395 ENSG00000183831 ENSG00000124762 ENSG00000196739 ENSG00000078804 ENSG00000198742 ENSG00000113558 ENSG00000135932 ENSG00000196498 ENSG00000105810 ENSG00000115594 ENSG00000087245 ENSG00000130826 ENSG00000182568 ENSG00000067057 ENSG00000100526 ENSG00000094804 ENSG00000180447 ENSG00000154217 ENSG00000198176 ENSG00000163235 ENSG00000111799 ENSG00000112378 ENSG00000152952 ENSG00000138798 ENSG00000050748 ENSG00000198793 ENSG00000095015 ENSG00000123104 ENSG00000087586 ENSG00000175066 ENSG00000166266 ENSG00000118971 ENSG00000179295 ENSG00000131669 ENSG00000112242 ENSG00000145623 ENSG00000185591 ENSG00000137834 ENSG00000005339 ENSG00000183691 ENSG00000058091 ENSG00000067900 ENSG00000134871 ENSG00000168610 ENSG00000174307 ENSG00000221823 ENSG00000198435 ENSG00000135446 ENSG00000050165 ENSG00000243646 ENSG00000080839 ENSG00000204217 ENSG00000102974 ENSG00000176619 PMC5146659__F5 Role and mechanism of the AMPK pathway in waterborne Zn exposure influencing the hepatic energy metabolism of Synechogobius hasta ENSG00000008710 ENSG00000198793 ENSG00000026103 PMC6186122__F3 Schematic of the extrinsic and intrinsic coagulation cascade ENSG00000180210 ENSG00000003436 ENSG00000134982 ENSG00000173599 ENSG00000088926 PMC6153639__F1 Folate structure and metabolic pathway ENSG00000228716 ENSG00000124479 ENSG00000095059 ENSG00000136877 PMC8534845__F1 Immunotherapy in Extensive-Stage Small Cell Lung Cancer ENSG00000149311 ENSG00000175054 ENSG00000169245 ENSG00000172716 ENSG00000136997 ENSG00000087586 ENSG00000090932 ENSG00000139687 ENSG00000139352 PMC5435901__F3 Curcumin plays a protective role at the priming and the activation stage of renal fibrosis ENSG00000069869 ENSG00000177606 ENSG00000168036 ENSG00000126353 PMC8692700__F2 Functional role of Pescadillo ribosomal biogenesis factor 1 in cancer ENSG00000141867 ENSG00000168036 ENSG00000168646 ENSG00000196628 ENSG00000100029 PMC2413058__F7 Myopic acts in the endocytic pathway to enhance signaling by the Drosophila EGF receptor ENSG00000110395 ENSG00000146648 PMC6952538__F3 Intermediates of the cholesterol biosynthetic pathway function as RORGagonists ENSG00000112972 ENSG00000172893 ENSG00000167910 ENSG00000113161 ENSG00000132196 ENSG00000138135 ENSG00000001630 ENSG00000116133 ENSG00000109929 ENSG00000149809 ENSG00000036530 ENSG00000104549 ENSG00000075239 PMC3781481__F2 Classic and alternative lipogenic pathways of fructose ENSG00000042832 ENSG00000100412 ENSG00000138030 ENSG00000116337 ENSG00000026103 PMC1601944__F1 HIF-dependent VHL pathways in oncogenesis ENSG00000134086 ENSG00000163235 ENSG00000146648 PMC6588196__F1 Possible sex effects on aspects of the CR/Met R mechanistic pathways ENSG00000105550 ENSG00000198793 PMC7934455__AF1 lncRNA SNHG11 Promotes Gastric Cancer Progression by Activating the Wnt/Beta-Catenin Pathway and Oncogenic Autophagy ENSG00000168036 ENSG00000139842 ENSG00000145782 PMC9410805__F7 Proanthocyanidins Activate Nrf2/ARE Signaling Pathway in Intestinal Epithelial Cells by Inhibiting the Ubiquitinated Degradation of Nrf2 ENSG00000178573 ENSG00000100387 ENSG00000173599 ENSG00000156273 ENSG00000079999 PMC8572421__F1 Contradictory roles of lipid metabolism in immune response within the tumor microenvironment ENSG00000135218 ENSG00000113161 ENSG00000169710 ENSG00000026103 PMC8303588__F2 TGFB Signaling: From Tissue Fibrosis to Tumor Microenvironment ENSG00000198793 PMC5595361__F1 Signaling pathways involved in GBM-induced apoptosis ENSG00000026103 PMC3417337__F1 Platinum drug action pathway ENSG00000012061 ENSG00000134899 ENSG00000136868 ENSG00000181019 ENSG00000167325 ENSG00000123191 ENSG00000005381 ENSG00000118777 ENSG00000134480 ENSG00000023839 ENSG00000136936 PMC8303588__F1 TGFB Signaling: From Tissue Fibrosis to Tumor Microenvironment PMC8572421__F3 Contradictory roles of lipid metabolism in immune response within the tumor microenvironment ENSG00000135218 ENSG00000198793 ENSG00000169710 ENSG00000118520 ENSG00000049768 ENSG00000038945 ENSG00000168610 PMC2575467__F5 A model of KCNQ1/KCNE1 function in embryogenesis ENSG00000100146 PMC6990114__F3 Hippo pathway plays vital role in mammalian immune system ENSG00000183735 ENSG00000164430 ENSG00000150907 ENSG00000049768 PMC5595361__F4 Interrelationships between programmed cell death ENSG00000102871 ENSG00000198793 ENSG00000172936 ENSG00000168040 ENSG00000175104 PMC6770252__F3 Biological origin of free radicals and their effect on cell viability ENSG00000128272 ENSG00000086991 ENSG00000100219 PMC6770252__F2 Three major branches of the Unfolded Protein Response (UPR) signaling pathway and their interconnections ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC6171904__F1 miR-451-AMPK-mTOR-cell cycle signaling pathway ENSG00000198793 ENSG00000135932 ENSG00000129355 PMC9257764__F5 Research progress of signaling pathways of the natural substances intervene dyslipidemia (Review) ENSG00000168610 ENSG00000026103 PMC9257764__F4 Research progress of signaling pathways of the natural substances intervene dyslipidemia (Review) ENSG00000150907 PMC12174925__F3 Dual Role of Autophagy in Periodontal Tissue under Periodontal Pathogen Infection and Diabetes Environment ENSG00000019991 ENSG00000185883 ENSG00000125538 ENSG00000198793 ENSG00000145782 PMC9281521__F5 Preliminary Study on Gene Regulation and its Pathways in Chinese Holstein Cows with Clinical Mastitis Caused by Staphylococcus Aureus ENSG00000171100 ENSG00000149782 ENSG00000049860 ENSG00000164171 ENSG00000281879 ENSG00000087460 ENSG00000158467 ENSG00000253710 ENSG00000143753 ENSG00000093217 ENSG00000115419 ENSG00000159399 ENSG00000116761 PMC6365498__F8 IPKB analysis of relationships among upregulated genes on silk film topography ENSG00000135547 ENSG00000148400 ENSG00000133961 ENSG00000105568 ENSG00000184916 ENSG00000168610 ENSG00000136068 ENSG00000091073 PMC6193676__F1 Importance of diphthamide modified EF2 for translational accuracy and competitive cell growth in yeast ENSG00000148399 ENSG00000134146 ENSG00000108963 PMC10298365__F5 Neonatal Meningitis-Causing Escherichia coli Induces Microglia Activation which Acts as a Double-Edged Sword in Bacterial Meningitis ENSG00000125538 PMC3514292__F1 Schematic representation depicting A; the protein synthesis pathway in skeletal muscle involving the mammalian target of rapamycin complex 1 (mTORC1) ENSG00000150907 ENSG00000169047 ENSG00000198793 ENSG00000096717 PMC4526643__F2 Transcriptomic Profiling of Virus-Host Cell Interactions following Chicken Anaemia Virus (CAV) Infection in an In Vivo Model ENSG00000291470 ENSG00000116044 ENSG00000182568 ENSG00000161533 PMC6952538__F1 RORGt functions play a central intermediary role in linking the control of cholesterol biosynthesis and metabolism to the regulation of immune responses and autoimmune disease ENSG00000084676 ENSG00000106546 PMC5916931__F4 Dual role for glucocorticoid-induced leucine zipper in glucocorticoid function: tumor growth promotion or suppression? ENSG00000288269 ENSG00000145321 ENSG00000174059 PMC6741141__F5 Metabolic pathway of aerial and submerged mycelia in the liquid surface culture of Cordyceps militaris ENSG00000144410 PMC4810089__F3 ARE- and GRE-signaling pathways stimulated through growth factors and growth hormones ENSG00000182901 ENSG00000291971 ENSG00000198793 ENSG00000116741 ENSG00000141068 ENSG00000117152 ENSG00000148908 ENSG00000172216 ENSG00000135446 ENSG00000010810 ENSG00000177606 ENSG00000136997 ENSG00000106070 ENSG00000185591 PMC11542495__F2 Cytoprotective Mechanisms of HO-1: Heme oxygenase 1 is an enzyme responsible for the breakdown of heme into Fe²⁺, CO, and bilirubin, which is subsequently converted to bilirubin by BVR ENSG00000167196 ENSG00000156273 ENSG00000079999 PMC4810089__F2 Kinase signaling pathways involved in T cell receptor activation ENSG00000291603 ENSG00000198793 ENSG00000020633 ENSG00000245848 ENSG00000117525 ENSG00000107338 ENSG00000159216 ENSG00000110395 ENSG00000213658 ENSG00000172216 ENSG00000010810 ENSG00000150907 ENSG00000113263 ENSG00000124181 ENSG00000135605 PMC11542495__F1 Schematic diagram of Nrf2 and Keap1 domain structure: Nrf2, is a transcription factor characterized by multiple functional domains, including Neh2, Neh4, Neh5, Neh6, Neh7, Neh1, and Neh3 ENSG00000079999 PMC7390945__F4 Some involved pathways in C8- and C10-treated cells, on the basis of Metabolic Pathway analysis ENSG00000131473 ENSG00000115419 ENSG00000026103 PMC6089198__F8 Mutation frequency of selected pathways ENSG00000134982 ENSG00000060237 ENSG00000232326 ENSG00000168036 ENSG00000108375 ENSG00000273686 ENSG00000100888 ENSG00000121879 ENSG00000175029 ENSG00000064012 ENSG00000164305 PMC7854758__F11 On the effect of antiresorptive drugs on the bone remodeling of the mandible after dental implantation: a mathematical model ENSG00000152266 ENSG00000117322 PMC3827695__F4 Women and Lung Cancer: What’s New? ENSG00000168610 ENSG00000146648 PMC3057165__F1 Pathways by which toll-like-receptor signals and ligation of FcG receptor lead to the production of interleukin ENSG00000172936 ENSG00000175104 PMC2770656__F4 The tyrosine metabolism pathway where the differentially expressed genes of lung cancer were annotated PMC9552026__F5 Development of degradable magnesium-based metal implants and their function in promoting bone metabolism (A review) ENSG00000092439 ENSG00000119121 PMC8774087__F1 Calcium Signaling Pathway Is Involved in the Shedding of ACE2 Catalytic Ectodomain: New Insights for Clinical and Therapeutic Applications of ACE2 for COVID-19 ENSG00000002330 ENSG00000130234 PMC11542495__F3 Regulatory mechanisms for Nrf2/HO-1 signaling pathway: Under normal conditions, Keap1 mediates the ubiquitination and proteasomal degradation of Nrf2 by binding to Nrf2 and interacting with the CUL3 ubiquitin ligase complex ENSG00000181019 ENSG00000178573 ENSG00000167468 ENSG00000177606 ENSG00000079999 PMC7317223__F4 Cell cycle and signalling pathway cascades in the Chinese ESCC subtypes ENSG00000134982 ENSG00000087586 ENSG00000145386 ENSG00000166851 ENSG00000145604 ENSG00000198901 ENSG00000148773 ENSG00000134057 ENSG00000109805 ENSG00000135446 ENSG00000112984 ENSG00000136997 ENSG00000123374 PMC10573125__F1 The JAK-STAT signaling pathway by LNK in hormone receptor-positive breast cancer and non-tumor cells ENSG00000137193 ENSG00000168610 ENSG00000113494 PMC4853852__F5 Genes under multiple regulatory controls in the PTEN pathway ENSG00000002330 ENSG00000292218 ENSG00000171791 ENSG00000164305 ENSG00000124762 ENSG00000081026 ENSG00000153721 ENSG00000046889 ENSG00000077782 ENSG00000126458 ENSG00000171105 ENSG00000197081 ENSG00000269335 ENSG00000164171 ENSG00000086015 ENSG00000066468 ENSG00000117020 ENSG00000110395 ENSG00000160867 ENSG00000067606 ENSG00000171608 ENSG00000115232 ENSG00000204217 ENSG00000105723 ENSG00000141655 PMC8267719__F3 Long Noncoding RNA GAS5 in Breast Cancer: Epigenetic Mechanisms and Biological Functions ENSG00000150907 ENSG00000198793 PMC7485347__F3 Functional and clinical significance of INI‐1/SMARCB1 ENSG00000168036 PMC3581421__F8 Coupling and S1P signaling in mesenchymal cells ENSG00000170989 ENSG00000267534 PMC4357835__F2 KEGG pathway analysis ENSG00000039537 ENSG00000003436 ENSG00000110799 ENSG00000181104 ENSG00000244731 ENSG00000166278 ENSG00000115718 ENSG00000185010 ENSG00000104368 ENSG00000180210 ENSG00000126218 ENSG00000117525 ENSG00000011422 PMC524335__F7 Regulation of angiogenesis by the ancillary receptor endoglin ENSG00000170365 PMC4674888__F12 LRRK2 in neurons in Parkinson's disease which is the fifth scored pathway map in MetaCore enrichment analysis results ENSG00000196961 ENSG00000183020 PMC8490651__F6 Curcumin Extraction, Isolation, Quantification and Its Application in Functional Foods: A Review With a Focus on Immune Enhancement Activities and COVID-19 ENSG00000069869 PMC4674888__F10 Cell cycle Role of SCF complex in cell cycle regulation which is the third scored pathway map in MetaCore enrichment analysis results ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000100387 ENSG00000134982 ENSG00000135446 ENSG00000113558 ENSG00000099804 ENSG00000166851 PMC2967529__F8 Model for vertebrate limb induction and outgrowth ENSG00000066468 ENSG00000070193 ENSG00000196923 ENSG00000089225 PMC6164894__F2 Canonical TGFB1 signaling pathway ENSG00000105329 PMC10551897__F9 SX Components-top 8 Targets-Pathways Network (Green hexagon node shows SX, pink circle nodes show the components, purple rectangle nodes show target genes, orange V-shape nodes show pathways and edges show the interaction between two nodes) ENSG00000291971 ENSG00000168610 ENSG00000146648 PMC10551897__F8 SX Components-Targets-Pathways Network (Green hexagon node shows SX, pink diamond nodes show the components, blue rectangle nodes show target genes, orange ellipse-shape nodes show pathways and edges show the interaction between two nodes) ENSG00000182578 ENSG00000157404 ENSG00000291971 ENSG00000198793 ENSG00000087586 ENSG00000101224 ENSG00000166851 ENSG00000073756 ENSG00000164305 ENSG00000122025 ENSG00000128052 ENSG00000123374 ENSG00000064012 ENSG00000146648 PMC11706781__F1 Angiogenic cascade and metabolic reprogramming of ECs in tumorigenesis ENSG00000092621 ENSG00000148400 ENSG00000169710 ENSG00000135069 ENSG00000070669 ENSG00000026103 PMC3009898__F6 Model for an alternative Okazaki fragment-processing pathway in vivo ENSG00000105486 ENSG00000138346 ENSG00000140451 PMC8533981__F5 Mechanisms of Plant-Derived Natural Products in the Treatment of Cervical Cancer ENSG00000198793 ENSG00000168036 PMC11706781__F3 Interactions between immune cells and tumor endothelial cells in the tumor microenvironment ENSG00000169710 ENSG00000112715 ENSG00000070669 ENSG00000135605 PMC1993906__F16 Adenylyl cyclases are targets of multiple regulatory signaling pathways and respond differently, depending on which group they belong to ENSG00000070831 ENSG00000291971 ENSG00000163914 ENSG00000149782 ENSG00000182621 ENSG00000137841 ENSG00000101333 PMC1993906__F13 The G12/13 signaling pathway ENSG00000135605 ENSG00000010671 PMC6595688__F1 PKM2: Junction of Metabolic Networks and Signal Cascades ENSG00000180210 ENSG00000122966 ENSG00000172005 PMC514949__F9 Multiple pathways involved in tumorigenesis by VEGF-null tumor cells ENSG00000173599 PMC7676225__F6 Caloric Restriction and Ketogenic Diet Therapy for Epilepsy: A Molecular Approach Involving Wnt Pathway and KATP Channels ENSG00000134982 ENSG00000198793 ENSG00000145979 ENSG00000168036 PMC7311749__F1 Multiple oxidative stress factors induce pneumonia and AMPK-Nrf2 pathway inhibits pulmonary ROS accumulation ENSG00000181019 ENSG00000175567 PMC3706521__F3 Gene expression changes in aging retinal microglia: relationship to microglial support functions and regulation of activation ENSG00000033327 ENSG00000002330 ENSG00000170458 ENSG00000149269 ENSG00000177606 ENSG00000164362 ENSG00000173039 ENSG00000164399 ENSG00000113520 ENSG00000185591 ENSG00000146648 ENSG00000026103 PMC8393955__F6 Implications of a ‘Third Signal’ in NK Cells ENSG00000162594 ENSG00000169245 ENSG00000096996 ENSG00000138378 ENSG00000105397 ENSG00000183625 ENSG00000138755 ENSG00000172936 ENSG00000105246 ENSG00000175104 ENSG00000069667 PMC3364930__F5 Subcellular localization of components of the PIWI-piRNA pathway and the proposed mechanism of TE suppression by this pathway ENSG00000142182 ENSG00000095627 ENSG00000143194 ENSG00000073146 PMC3706521__F4 Gene expression changes in aging retinal microglia: relationship to microglial support functions and regulation of activation ENSG00000135218 ENSG00000070831 ENSG00000163235 ENSG00000128052 ENSG00000100985 ENSG00000112715 PMC4955761__F8 Pulmonary Epithelial Toll-like Receptor 4 Activation leads to Lung Injury in Neonatal Necrotizing Enterocolitis ENSG00000189403 ENSG00000136869 PMC10502204__F2 ctDNA as a novel and promising approach for cancer diagnosis: a focus on hepatocellular carcinoma ENSG00000149311 ENSG00000175054 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000164362 ENSG00000168036 ENSG00000171863 PMC5434066__F8 Schematic diagram of Bc-specific induction of regulatory T cells via suppression of mTOR signaling pathway ENSG00000118515 ENSG00000107485 ENSG00000049768 ENSG00000168610 PMC8047446__EV5 GOLPH3‐driven functional enzyme module ENSG00000113384 ENSG00000141086 PMC4198693__F5 Identification of molecular pathways that are altered by Atbf1 inactivation in mouse prostates ENSG00000153898 ENSG00000138792 ENSG00000123411 ENSG00000184292 ENSG00000197208 ENSG00000135373 ENSG00000070669 ENSG00000106546 ENSG00000053747 ENSG00000065328 ENSG00000291507 ENSG00000156427 ENSG00000118849 ENSG00000166123 PMC4066335__F3 All diabetes drugs are likely to have indirect effects in the CNS by affecting circulating concentrations of glucose and insulin ENSG00000169047 ENSG00000168610 PMC5893801__F1 Therapeutic strategies to enhance immune checkpoint inhibitors by targeting tumor-associated macrophages (TAM) ENSG00000182578 ENSG00000118520 PMC5927721__F1 MiRNAs targeting the IGF1R pathway in its entirety ENSG00000169291 ENSG00000002330 ENSG00000150907 PMC5711834__F16 Schematic model of the Keap1/Nrf2 signaling pathway ENSG00000178573 ENSG00000079999 PMC6592248__F8 Proposed model to explain the molecular mechanism of Bmal1 deficiency influenced the HIF1Alpha-VEGF axis in the chondrocytes ENSG00000173599 PMC8920499__F1 Expression levels of sonic hedgehog pathway genes and their targets are upregulated in early clear cell renal cell carcinoma ENSG00000106571 ENSG00000136997 ENSG00000164690 ENSG00000171791 ENSG00000112715 ENSG00000128602 PMC5850311__F1 Research and therapeutics—traditional and emerging therapies in systemic lupus erythematosus PMC6652233__F3 Stimulation of TLRs activates multiple signaling pathways ENSG00000170458 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000164342 PMC9524569__F1 Protective role of ethyl pyruvate in spinal cord injury by inhibiting the high mobility group box-1/toll-like receptor4/nuclear factor-kappa B signaling pathway ENSG00000242689 ENSG00000163235 ENSG00000138798 ENSG00000125538 PMC7281705__F3 Ang1 and Ang2 bind to Tie2 with similar affinities; however, whereas Ang1 is an agonist, the ability of Ang2 to activate Tie2 appears to depend on the cell type and context ENSG00000149269 ENSG00000138798 ENSG00000099194 PMC7676225__F1 Metabolic effect of Wnt promotes the absorption of glucose in the neuron by increasing the affinity of the GLUT3 transporter for its substrate ENSG00000134982 ENSG00000198793 ENSG00000145979 ENSG00000168036 PMC6437932__F8 Working model ENSG00000146457 PMC10380571__F2 Vascular Ageing: Mechanisms, Risk Factors, and Treatment Strategies ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000163961 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC8353884__F7 Proposed Model of IKK:NFKB:Notch Signaling Control by SLX4IP and RAP1 ENSG00000149346 ENSG00000135547 ENSG00000168214 ENSG00000188827 ENSG00000033800 ENSG00000164362 ENSG00000114315 PMC7175209__F1 Induction and initiation of cellular growth control and senescence via p53 or P16INK4A pathways ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000105810 PMC6683960__F1 Gold nanoparticles-loaded hydroxyapatite composites guide osteogenic differentiation of human mesenchymal stem cells through Wnt/Beta-catenin signaling pathway ENSG00000134982 ENSG00000168036 PMC9531660__F3 Species-specific transcriptomic changes upon respiratory syncytial virus infection in cotton rats ENSG00000132906 ENSG00000112576 ENSG00000160710 ENSG00000168040 ENSG00000122194 ENSG00000164305 ENSG00000276561 ENSG00000150782 ENSG00000111537 ENSG00000135446 ENSG00000125538 ENSG00000160703 ENSG00000110713 ENSG00000136869 ENSG00000131323 ENSG00000105810 ENSG00000135828 ENSG00000121060 ENSG00000140464 ENSG00000026103 ENSG00000164342 PMC7663720__F2 Pharmacological inhibitors targeting the Wnt pathway that are currently being tested for cancer treatment ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC7663720__F1 Wnt signaling pathway ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000070831 ENSG00000134982 ENSG00000163914 ENSG00000177606 ENSG00000185483 ENSG00000168036 PMC7226210__F2 The most relevant molecular pathways and targeted agents in TNBC ENSG00000012048 ENSG00000169047 PMC6271057__F5 GSK3B and phospho-GSK3B regulate milk synthesis and DCMEC proliferation via the mTOR/S6K1 signaling pathway ENSG00000198793 ENSG00000099194 ENSG00000026103 PMC9280125__F1 Homocysteine Metabolism in Pregnancy and Developmental Impacts ENSG00000228716 PMC11932845__F1 FGF/FGFR signalling pathway in mammary epithelium and TNBC PMC10242111__F4 Venetoclax durable response in adult relapsed/refractory Philadelphia-negative acute lymphoblastic leukemia with JAK/STAT pathway alterations ENSG00000120833 ENSG00000119535 ENSG00000112964 ENSG00000117400 ENSG00000173757 ENSG00000198793 ENSG00000136997 ENSG00000171791 ENSG00000168610 PMC6358786__F4 Alterations of the PI3K/Akt-Cyclin D1 pathway in cell cycle progression from G1 to S phase in 2-cell embryos ENSG00000149311 ENSG00000184524 ENSG00000135446 ENSG00000069188 ENSG00000105810 PMC9288709__F5 Transcriptome profiling and co-expression network analysis of lncRNAs and mRNAs in colorectal cancer by RNA sequencing ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000136997 ENSG00000104894 PMC8246550__F3 Epigenetic regulation of cancer stem cell formation and maintenance ENSG00000151376 ENSG00000187605 ENSG00000138336 ENSG00000139372 ENSG00000088926 ENSG00000113360 PMC4114568__F4 PleiotRHOpic ENSG00000038382 ENSG00000070831 ENSG00000177963 ENSG00000204138 ENSG00000149269 ENSG00000112655 ENSG00000136160 ENSG00000121966 ENSG00000284984 PMC7403980__F7 Mechanistic scheme of anti-inflammatory signaling pathways of KMU-470 ENSG00000162711 ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC6458768__F1 CD22 structure and signaling pathway ENSG00000186716 PMC6502913__F7 USP7 functions in several canonical signaling pathways ENSG00000148400 ENSG00000168036 PMC3040416__F3 Proteins oxidized by extracellular EhCySS control cell signaling and morphology ENSG00000182774 ENSG00000133110 ENSG00000073578 ENSG00000105193 ENSG00000197102 ENSG00000198743 ENSG00000100345 ENSG00000197879 ENSG00000136026 ENSG00000165280 ENSG00000174444 PMC6284331__F1 Effect of changes in ECM‐mediated signalling pathways ENSG00000162733 ENSG00000291971 ENSG00000163914 ENSG00000026508 ENSG00000132478 PMC4107774__F1 The Hippo signalling core cassette in mammals ENSG00000150457 ENSG00000131023 PMC8396993__F1 Perspectives on Precision Medicine in Chronic Lymphocytic Leukemia: Targeting Recurrent Mutations—NOTCH1, SF3B1, MYD88, BIRC3 ENSG00000128917 ENSG00000198435 ENSG00000136997 ENSG00000184916 ENSG00000137845 ENSG00000090932 ENSG00000124762 PMC3083963__F1 Brain-derived neurotrophic factor (BDNF) gene and stimulated intracellular signaling cascades after activation of tropomyosin-related kinase (Trk)B ENSG00000169291 PMC8394001__F3 Guardians of the Genome: BRCA2 and Its Partners ENSG00000012048 ENSG00000083093 ENSG00000134086 ENSG00000138346 ENSG00000144554 ENSG00000164306 ENSG00000187741 ENSG00000051180 ENSG00000077514 ENSG00000138375 ENSG00000139618 PMC10840523__F1 Therapeutic Potential of Fingolimod in Diabetes Mellitus and Its Chronic Complications ENSG00000170989 ENSG00000180739 ENSG00000213694 ENSG00000125910 ENSG00000267534 PMC11978054__F11 Impact of hydroxyurea and metformin on Gamma-globin induction involves complex molecular pathways ENSG00000102145 ENSG00000185022 ENSG00000002330 ENSG00000285222 ENSG00000105610 ENSG00000135363 ENSG00000185591 ENSG00000136826 PMC3437205__F3 Pathway analysis of the hypermethylated genes in lymph node metastasis including their biological processes and association to breast carcinogenesis and neoplasm metastasis ENSG00000012048 ENSG00000134982 PMC9603382__F1 Pathogenesis of Port-Wine Stains: Directions for Future Therapies ENSG00000198793 ENSG00000149782 ENSG00000091879 ENSG00000112715 PMC3748765__F1 TCDD-induced CTLA-4 on AhR-Treg activating the tolerogenic IDO pathway and suppressing the acute GVH response ENSG00000111537 ENSG00000115415 ENSG00000106546 PMC7840460__F7 Dmrt1 repressing immune response but promoting proliferation of mGSCs ENSG00000137090 ENSG00000136869 ENSG00000131323 ENSG00000175104 PMC8964056__F4 Phosphorylation-Dependent Regulation of WNT/Beta-Catenin Signaling ENSG00000169071 ENSG00000100592 ENSG00000185483 PMC10308077__F2 Friend or foe for obesity: How hepatokines remodel adipose tissues and translational perspective ENSG00000115226 ENSG00000105550 ENSG00000026508 ENSG00000132855 ENSG00000136235 ENSG00000096717 ENSG00000132170 PMC4810646__F1 OAS-RNase L pathway ENSG00000187608 ENSG00000105397 ENSG00000115415 ENSG00000185745 ENSG00000135828 ENSG00000142166 PMC8251975__F3 Wnt/B‐catenin signaling: Structure, assembly and endocytosis of the signalosome ENSG00000102189 ENSG00000070831 ENSG00000149269 ENSG00000074319 PMC4294682__F6 Proposed model of hPer2 and hp53 interaction and function ENSG00000175793 PMC9038718__F7 Mechanism by which LINC00858 affects colon cancer ENSG00000081154 ENSG00000168610 PMC4736325__F2 Synaptic binding partners and signaling pathways of BAI adhesion-GPCRs ENSG00000131094 ENSG00000156299 ENSG00000163914 PMC11554578__F2 Exemplary Ca2+ signaling microdomains ENSG00000092439 ENSG00000167323 ENSG00000198838 ENSG00000293604 ENSG00000196218 ENSG00000198626 PMC3675375__F1 Wnt signaling pathway in diabetes mellitus ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4266039__F7 Biological activities of triterpenoids and saponins in animals ENSG00000163739 ENSG00000171791 ENSG00000100985 ENSG00000168610 ENSG00000146648 ENSG00000121966 PMC3543845__F2 Top network, “DNA Replication, Recombination, and Repair, Gene Expression, Cancer”, formed by genes exhibiting altered expression in MLT-pretreated MCF-7 cells upon MMS exposure relative to untreated MMS-exposed cells ENSG00000264364 ENSG00000157617 ENSG00000170043 ENSG00000182923 ENSG00000165392 ENSG00000204524 ENSG00000108506 ENSG00000174428 ENSG00000196407 ENSG00000076382 ENSG00000117322 ENSG00000111224 PMC9540430__F8 Transcriptomics for child and adolescent tuberculosis ENSG00000180182 ENSG00000159128 ENSG00000213928 ENSG00000285321 ENSG00000187608 ENSG00000089127 ENSG00000157601 ENSG00000173039 ENSG00000185745 ENSG00000027697 ENSG00000185885 ENSG00000038002 ENSG00000111537 ENSG00000105397 ENSG00000185201 PMC7033203__F2 Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis ENSG00000110921 ENSG00000197429 ENSG00000038002 ENSG00000167508 PMC5297991__F3 Functional analysis of the network containing validated segregating variants ENSG00000105397 PMC4215617__F3 MAPKs in the DAMP perception in innate immune cells ENSG00000175352 ENSG00000172936 ENSG00000136869 PMC9682695__F1 Early postnatal alterations in follicular stress response and survival in a mouse model of Classic Galactosemia ENSG00000128272 PMC11215075__F5 Ezetimibe, Niemann-Pick C1 like 1 inhibitor, modulates hepatic phospholipid metabolism to alleviate fat accumulation ENSG00000151726 ENSG00000042832 ENSG00000134824 ENSG00000173599 ENSG00000133027 PMC3586350__F8 Proposed Adipose Stromal Cell-derived IL-6 signaling pathway ENSG00000105397 ENSG00000168610 PMC6175696__F5 CA biosynthetic pathway starting from C3 and C5 precursors ENSG00000171759 ENSG00000084774 PMC8704776__F2 Telomeres and Cancer ENSG00000166340 ENSG00000178971 ENSG00000145912 ENSG00000291996 ENSG00000116754 PMC4813474__F10 Proposed model of the p8-regulated autophagy signaling pathway in response to palmitic acid stress ENSG00000128272 ENSG00000144895 PMC3143721__F5 Putative crosstalk between D1and TrkB receptors in striatal direct pathway neurons controlling PPD mRNA expression ENSG00000078053 PMC4126105__F1 Proposed integrated model for tissue-type plasminogen activator (tPA)- and plasminogen (Plgn)-mediated modulation of blood–brain barrier (BBB) permeability during thrombolysis in ischemic stroke ENSG00000130164 ENSG00000134853 ENSG00000197563 ENSG00000121807 PMC8458751__F7 Analysis of miRNAs Profiles in Serum of Patients With Steatosis and Steatohepatitis ENSG00000122966 ENSG00000107798 ENSG00000127948 PMC6966475__F3 EMT inducers from the chronic tumor microenvironment and EMT repressors from natural anti-inflammatory compounds and pro-resolving lipids ENSG00000138798 ENSG00000170558 ENSG00000189403 ENSG00000096717 ENSG00000175104 ENSG00000168610 PMC3921497__F4 Chitinase 3-like 1-associated Beta-catenin activation signaling pathway, which is inhibited by methylxanthine derivatives ENSG00000168036 PMC3392648__F1 Insulin signaling pathways ENSG00000171105 ENSG00000002330 PMC3025702__F2 Combination Treatment with Progesterone and Vitamin D Hormone May Be More Effective than Monotherapy for Nervous System Injury and Disease ENSG00000002330 PMC9388302__F2 Essential Role of FoxO1 in the Regulation of Macrophage Function ENSG00000150907 ENSG00000077463 ENSG00000096717 ENSG00000140464 PMC9530868__F7 Ubiquitin‐specific protease 28 deubiquitinates TCF7L2 to govern the action of the Wnt signaling pathway in hepatic carcinoma ENSG00000134982 ENSG00000168036 ENSG00000048028 ENSG00000109670 PMC11126050__F7 KIT structure and signalling ENSG00000157404 ENSG00000198793 ENSG00000167900 PMC5489693__F7 Gene interaction network related to lipid metabolism of DEGs between WC and WRR chickens ENSG00000130304 ENSG00000112977 ENSG00000138347 ENSG00000143970 ENSG00000010818 ENSG00000107372 ENSG00000152492 PMC6405884__F3 Schematics shown miRNAs which might regulate mGluR/mTOR/LTD signaling ENSG00000198793 PMC6156597__F13 Mapping of the DE genes exclusive to the oval morphotype on KEGG metabolic pathways– ENSG00000163930 ENSG00000187957 ENSG00000128272 ENSG00000160224 ENSG00000188404 ENSG00000162924 ENSG00000198168 ENSG00000140464 PMC3281623__F9 Toxoplasma acquires fatty acids through a complex network of synthesis and uptake ENSG00000011007 ENSG00000154582 PMC8744729__F2 Ribosomal Protein S6: A Potential Therapeutic Target against Cancer? ENSG00000130413 ENSG00000023287 ENSG00000170558 ENSG00000166851 ENSG00000292210 ENSG00000129219 ENSG00000134086 ENSG00000011566 ENSG00000184110 ENSG00000136997 ENSG00000135932 ENSG00000123374 ENSG00000105810 ENSG00000124181 ENSG00000177169 ENSG00000168209 ENSG00000151632 ENSG00000168610 ENSG00000136048 ENSG00000187134 ENSG00000149311 ENSG00000173805 ENSG00000144895 ENSG00000135446 ENSG00000106263 ENSG00000205629 ENSG00000132646 ENSG00000198074 ENSG00000096717 PMC7864206__F1 Essential molecules of the mammalian Hedgehog signaling pathway and their interactions ENSG00000106571 ENSG00000154309 ENSG00000128602 PMC4003416__F2 Targets of Twist proteins in the DNA damage response pathway ENSG00000149311 ENSG00000175054 ENSG00000136997 PMC1502028__F4 EGFR and mTOR signaling network, and signaling mediator effects associated with rapamycin and/or EKI-785 treatments ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC8004491__F1 Two pathways that collect and deliver axonal cargo for degradation in lysosomes ENSG00000145782 ENSG00000057663 PMC6156597__F14 Mapping of the DE genes exclusive to the oval morphotype on the SNARE interactions in vesicular transport pathway issued from the KEGG metabolic pathway– ENSG00000053501 ENSG00000135604 ENSG00000170310 ENSG00000135823 ENSG00000168818 ENSG00000079950 ENSG00000111450 ENSG00000099940 ENSG00000102003 ENSG00000149418 ENSG00000292366 PMC7595202__F6 Indole hydrazide compound ZJQ-24 inhibits angiogenesis and induces apoptosis cell death through abrogation of AKT/mTOR pathway in hepatocellular carcinoma ENSG00000169047 PMC7230310__F6 Knockout of IRF7 Highlights its Modulator Function of Host Response Against Avian Influenza Virus and the Involvement of MAPK and TOR Signaling Pathways in Chicken ENSG00000150782 ENSG00000183735 ENSG00000115415 ENSG00000157601 ENSG00000175104 ENSG00000276561 ENSG00000160917 PMC5842190__F5 Proposed pathway for regulation of endothelial cell signaling by breast cancer cell-derived EVs and a function-blocking CD47 antibody ENSG00000198053 PMC3193436__F1 Model describing the proposed role of Rap1GAP in the control of GDNF-induced Ret signaling ENSG00000076864 ENSG00000070831 ENSG00000156299 ENSG00000125170 ENSG00000160293 PMC5811339__F1 Hydrolytic enzymes tested in this study participate in sphingolipid metabolism in the lysosome as indicated by their respective gene names (blue) ENSG00000170266 PMC4304881__F5 Summary of results of RPPA analysis of EGFR signaling in MCF‐10A + EGF, MCF‐10A + AREG and SUM‐149 cells ENSG00000172680 ENSG00000033327 ENSG00000109321 ENSG00000291971 ENSG00000134982 ENSG00000198793 ENSG00000169710 ENSG00000150093 ENSG00000164327 ENSG00000168610 ENSG00000146648 PMC5864190__F1 Models of RIPK1 regulation by IKKA/B and MK2 phosphorylation ENSG00000137275 ENSG00000136869 PMC3733802__F2 Prioritizing Disease Candidate Proteins in Cardiomyopathy-Specific Protein-Protein Interaction Networks Based on “Guilt by Association” Analysis ENSG00000160808 ENSG00000198947 PMC4402072__F5 Schematic model of AREG in the Warburg effect and tumorigenesis ENSG00000109321 ENSG00000108788 ENSG00000146648 PMC8327086__F8 Berberine Reduces AB42 Deposition and Tau Hyperphosphorylation via Ameliorating Endoplasmic Reticulum Stress ENSG00000142192 ENSG00000042832 PMC8469852__F3 Kynurenine Pathway of Tryptophan Metabolism in Migraine and Functional Gastrointestinal Disorders ENSG00000110711 ENSG00000106546 PMC6941108__F3 Visualization of lncRNAs and mRNAs in enriched pathways ENSG00000163568 ENSG00000123485 ENSG00000131153 ENSG00000196743 ENSG00000158517 ENSG00000166851 ENSG00000093009 ENSG00000072571 ENSG00000137807 ENSG00000169429 ENSG00000282899 ENSG00000171320 ENSG00000131747 ENSG00000101057 ENSG00000167900 ENSG00000117399 ENSG00000117724 ENSG00000094804 ENSG00000019582 ENSG00000146670 ENSG00000275214 ENSG00000065328 ENSG00000117650 ENSG00000134057 ENSG00000156970 ENSG00000109805 ENSG00000112984 ENSG00000171848 ENSG00000175305 ENSG00000090659 PMC5364818__F2 Canonical and Noncanonical Inflammasome ENSG00000162711 ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000168040 PMC9688488__F4 HIF-1A Regulates Bone Homeostasis and Angiogenesis, Participating in the Occurrence of Bone Metabolic Diseases ENSG00000100234 ENSG00000087245 ENSG00000137673 ENSG00000149968 ENSG00000198793 ENSG00000166670 ENSG00000100985 PMC12162297__F1 Mechanisms by which a high-fat diet (HFD) affects hematopoietic stem cells (HSCs) ENSG00000148400 ENSG00000136869 PMC9688488__F1 HIF-1A Regulates Bone Homeostasis and Angiogenesis, Participating in the Occurrence of Bone Metabolic Diseases ENSG00000137033 ENSG00000148400 ENSG00000168610 PMC12162297__F2 High-fat diet (HFD) and energy-restricted diet modulate the function of hematopoietic stem cells (HSCs) ENSG00000198198 PMC8238937__F1 MYD88, NFKB1, and IL6 transcripts overexpression are associated with poor outcomes and short survival in neonatal sepsis ENSG00000174125 ENSG00000108691 ENSG00000239732 ENSG00000115415 ENSG00000187554 ENSG00000169429 ENSG00000172936 ENSG00000136869 ENSG00000184216 ENSG00000164342 PMC7791172__F1 NOD2 regulates AMP A‐defensins expression and AMPs sorting in PCs ENSG00000104856 ENSG00000167207 ENSG00000162924 ENSG00000104388 ENSG00000102678 PMC4710177__F2 Ribosomal Proteins and Human Diseases: Pathogenesis, Molecular Mechanisms, and Therapeutic Implications ENSG00000149311 ENSG00000175054 PMC3255869__F1 TLR4 signaling pathway ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC8774788__F5 Metformin Affects the Transcriptomic Profile of Chicken Ovarian Cancer Cells ENSG00000099866 ENSG00000019991 ENSG00000089154 ENSG00000134321 ENSG00000137673 ENSG00000109320 ENSG00000170231 ENSG00000091879 ENSG00000167900 ENSG00000168610 PMC10384366__F11 Natural Products Regulation of Molecular Signaling Pathway in Dermal Papilla Stem Cells ENSG00000071564 ENSG00000125398 ENSG00000168036 ENSG00000136826 PMC7785807__F4 miRNA expression on cellular connectivity and activities with different Toll-like receptor regulation and molecular function of the cellular signaling pathways (A) ENSG00000174125 ENSG00000183625 ENSG00000168040 ENSG00000150455 ENSG00000276561 ENSG00000143387 ENSG00000183735 ENSG00000144410 ENSG00000170458 ENSG00000187554 ENSG00000113520 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC6614373__F3 Signaling crosstalk at receptors and adaptors ENSG00000170458 ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC6614373__F2 NFKB signaling pathway ENSG00000239732 ENSG00000102871 ENSG00000082512 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000127191 ENSG00000184216 ENSG00000164342 PMC6614373__F1 Pathogen-Responsive NFKB ENSG00000111537 ENSG00000170458 ENSG00000115415 ENSG00000172936 ENSG00000136869 PMC8981087__F2 Autophagy in the Function of CD4+ T Cells and the Development of Chronic Inflammatory Diseases ENSG00000026508 ENSG00000047936 PMC8116828__F1 Targeting Sphingosine-1-Phosphate Signaling in Immune-Mediated Diseases: Beyond Multiple Sclerosis ENSG00000215021 ENSG00000118785 ENSG00000183018 ENSG00000174611 ENSG00000072080 PMC5851872__F1 Molecular Regulation of Follicle-Stimulating Hormone Synthesis, Secretion and Action ENSG00000109163 ENSG00000168066 ENSG00000168036 ENSG00000162772 PMC7982593__F7 Graph abstract HCC manifestation is typically preceded by hepatic fibrosis and cirrhosis ENSG00000136997 ENSG00000150457 PMC12036158__F3 Regulation of epithelial-mesenchymal transition (EMT) in idiopathic pulmonary fibrosis (IPF) by ferroptosis ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000156273 PMC12036158__F2 Regulatory pathways of ferroptosis ENSG00000168003 ENSG00000151012 ENSG00000197635 ENSG00000111684 ENSG00000102967 ENSG00000127948 PMC9570383__F2 Metabolic Reprogramming in Tumor Endothelial Cells ENSG00000180210 ENSG00000092621 ENSG00000135069 ENSG00000083720 ENSG00000070669 ENSG00000135605 ENSG00000115419 ENSG00000159399 PMC7911352__F2 Cyst(e)ine-glutathione-GPX4 axis regulates ferroptosis ENSG00000163930 ENSG00000128272 ENSG00000151012 ENSG00000167468 ENSG00000179918 PMC6337248__F1 Intracellular signaling pathways that regulate Nrf2 ENSG00000178573 ENSG00000079999 PMC7911352__F4 Other metabolic pathways that regulate ferroptosis ENSG00000135423 ENSG00000069869 ENSG00000078668 ENSG00000167468 ENSG00000284099 ENSG00000017483 PMC3694431__F5 Interaction networks of significantly regulated genes from interconnected neurons 7 days post-infarct ENSG00000100234 ENSG00000160789 ENSG00000097033 ENSG00000143248 ENSG00000163083 ENSG00000138071 ENSG00000132510 ENSG00000092820 ENSG00000089159 ENSG00000066044 ENSG00000171150 ENSG00000198742 ENSG00000220205 ENSG00000197386 ENSG00000185591 ENSG00000138100 ENSG00000132535 ENSG00000126458 ENSG00000171885 ENSG00000107779 ENSG00000110711 ENSG00000114450 ENSG00000291355 ENSG00000100285 ENSG00000148400 ENSG00000078369 ENSG00000127955 ENSG00000065135 ENSG00000145604 ENSG00000277586 ENSG00000112232 ENSG00000132692 ENSG00000185033 ENSG00000165156 ENSG00000101327 ENSG00000167755 PMC4087127__F2 Scheme of ErbB dimers related MAPK and PI3K pathway activation ENSG00000113905 ENSG00000065361 ENSG00000138798 ENSG00000198793 PMC9143262__F2 Platelet-Derived Growth Factor Pathway in Pulmonary Arterial Hypertension: Still an Interesting Target? ENSG00000145431 ENSG00000170962 PMC3567829__F9 miR-486 sustains NFKB activity by disrupting multiple NFKB-negative feedback loops ENSG00000078747 ENSG00000102871 ENSG00000083799 PMC11153983__F6 Illustration of the mechanism of DHA inhibiting T-ALL cell viability, inducing ferroptosis by modulating the SLC7A11-GPX4 signaling pathway and provoking ER stress ENSG00000168003 ENSG00000128272 ENSG00000151012 ENSG00000167468 PMC9143262__F4 Platelet-Derived Growth Factor Pathway in Pulmonary Arterial Hypertension: Still an Interesting Target? ENSG00000167323 ENSG00000115415 ENSG00000293604 ENSG00000198793 ENSG00000036828 ENSG00000184481 ENSG00000168610 PMC2951227__F7 Hypothetical model for Rad18-dependent activation of the FA pathway in response to bulky DNA adducts ENSG00000132646 ENSG00000070950 ENSG00000130997 ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000166508 PMC8235983__F5 Study on the Molecular Mechanism of the Herbal Couple Sparganii Rhizoma-Curcumae Rhizoma in the Treatment of Lung Cancer Based on Network Pharmacology ENSG00000149311 ENSG00000142192 ENSG00000136997 ENSG00000124795 ENSG00000174611 PMC12061915__F1 Macrophages in cSCC ENSG00000133048 ENSG00000146072 ENSG00000091972 ENSG00000118520 ENSG00000143387 PMC11174690__F5 SIRT signaling pathway by active ingredients in goji berries ENSG00000150907 ENSG00000096717 ENSG00000142082 ENSG00000106459 ENSG00000026103 PMC8178373__F2 Two common mechanisms of aurora kinase A (AURKA) synthetic lethal interactions ENSG00000117713 ENSG00000087586 ENSG00000139687 ENSG00000127616 PMC11174690__F4 PI3K-Akt signaling pathway by active ingredients in goji berries ENSG00000162711 ENSG00000150907 ENSG00000198793 ENSG00000171791 PMC11174690__F3 Fas/Fasl signaling pathway by active ingredients in goji berries ENSG00000168040 ENSG00000164305 ENSG00000026103 PMC8149889__F2 Decidual Natural Killer Cells: A Good Nanny at the Maternal-Fetal Interface During Early Pregnancy ENSG00000105894 ENSG00000277336 ENSG00000143185 ENSG00000104972 ENSG00000276051 ENSG00000276387 PMC7692643__F6 Proposed mechanisms of YAP/TAZ activation in CMS4 CRC ENSG00000134982 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC7692643__F2 Hippo pathway ENSG00000150457 ENSG00000131023 PMC2971463__F3 SLIT/ROBO pathway: a regulator of cell function with implications for the reproductive system ENSG00000124102 ENSG00000019991 ENSG00000168036 ENSG00000121966 PMC6670099__F10 The role of PLIP1 in TAG biosynthesis during development of wild-type (WT) and dgat1 seed ENSG00000087253 ENSG00000173599 ENSG00000285482 ENSG00000198670 ENSG00000026103 PMC3983565__F4 MAPK signalling cooperates with loss of APC to promote adenoma development ENSG00000134982 ENSG00000168036 ENSG00000146648 ENSG00000104081 PMC5026403__F2 Complement activation and immune regulation ENSG00000274619 ENSG00000166278 PMC7520283__F2 DNA methylation and histone acetylation involved in OA‐FLS inflammation ENSG00000125538 ENSG00000169047 ENSG00000162692 ENSG00000175104 ENSG00000168610 PMC7520283__F1 MiRNAs involved in OA‐FLS inflammation ENSG00000108691 ENSG00000125538 ENSG00000198793 ENSG00000185591 PMC9616825__F8 Schematic illustrating the working model of diabetes-induced bone marrow dysfunction ENSG00000107562 ENSG00000105329 ENSG00000291837 ENSG00000132170 PMC7520283__F4 Wnt/B‐catenin signalling pathway in OA‐FLS inflammation ENSG00000134982 ENSG00000168036 ENSG00000168610 PMC7520283__F3 Activated NF‐KB signalling pathway in OA‐FLS inflammation ENSG00000125538 ENSG00000162692 PMC3017463__F4 Schematic illustartion of microglial (A) and astrocytic (B) events taking place in the spinal cord in neuropathic pain ENSG00000108691 PMC10573612__F2 Exploring the Cellular and Molecular Mechanism of Discoidin Domain Receptors (DDR1 and DDR2) in Bone Formation, Regeneration, and Its Associated Disease Conditions ENSG00000162733 ENSG00000163914 PMC8070386__F2 Influence of extracellular acidification on melanoma progression ENSG00000167601 ENSG00000087245 ENSG00000100985 ENSG00000136826 ENSG00000084774 PMC8273913__F4 Integrated Analysis of Microarray and RNA-Seq Data for the Identification of Hub Genes and Networks Involved in the Pancreatic Cancer ENSG00000112977 ENSG00000019991 ENSG00000070831 ENSG00000163235 ENSG00000138798 ENSG00000198793 ENSG00000112715 PMC9223566__F6 Exercise Training Enhances BDNF/TrkB Signaling Pathway and Inhibits Apoptosis in Diabetic Cerebral Cortex ENSG00000002330 ENSG00000171791 ENSG00000168040 PMC6321433__F3 Cholesterol biosynthesis deficiency syndromes ENSG00000162711 ENSG00000110921 ENSG00000125538 ENSG00000127948 PMC8273913__F3 Integrated Analysis of Microarray and RNA-Seq Data for the Identification of Hub Genes and Networks Involved in the Pancreatic Cancer ENSG00000070831 ENSG00000138798 ENSG00000163914 PMC7468434__F1 Mitochondrial dysfunction in microglia ENSG00000162711 ENSG00000135218 ENSG00000156026 PMC8533960__F3 Systems Approach to Interrogate Gene Expression Patterns in African American Men Presenting with Clinically Localized Prostate Cancer ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000002330 ENSG00000069482 ENSG00000186716 ENSG00000169047 ENSG00000183691 ENSG00000115718 ENSG00000197601 PMC8662355__F2 Roles of Gasdermin D in Coronavirus Infection and Evasion ENSG00000278718 ENSG00000162711 ENSG00000081051 PMC3382127__F7 Toll-Like Receptor 3 and Suppressor of Cytokine Signaling Proteins Regulate CXCR4 and CXCR7 Expression in Bone Marrow-Derived Human Multipotent Stromal Cells ENSG00000115415 ENSG00000125347 ENSG00000121966 ENSG00000164342 PMC8533960__F5 Systems Approach to Interrogate Gene Expression Patterns in African American Men Presenting with Clinically Localized Prostate Cancer ENSG00000136457 ENSG00000135218 ENSG00000110799 ENSG00000026508 PMC8485071__F6 Stress Granules Involved in Formation, Progression and Metastasis of Cancer: A Scoping Review PMC8162686__F2 Peg3 downstream genes involved in major metabolic pathways ENSG00000131473 ENSG00000113161 ENSG00000169710 ENSG00000101365 PMC11754522__F1 Ceramide biosynthesis pathways (created by Figdraw 2 ENSG00000139624 ENSG00000100422 ENSG00000223802 ENSG00000154227 ENSG00000102172 ENSG00000143418 ENSG00000026103 PMC11754522__F3 Mechanisms by which nutritional interventions alter ceramide metabolism (created by Figdraw 2 ENSG00000139624 ENSG00000223802 ENSG00000154227 ENSG00000102172 ENSG00000143418 PMC10382948__F1 Hylemon-Björkhem pathway of bile acid 7-dehydroxylation: history, biochemistry, and microbiology ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC5041507__F1 Pathway interaction network of targets of apoptomiRs in breast cancer ENSG00000167601 ENSG00000100234 ENSG00000147649 ENSG00000152642 ENSG00000138792 ENSG00000107443 ENSG00000198793 ENSG00000108443 ENSG00000175592 ENSG00000101266 ENSG00000171791 ENSG00000187266 ENSG00000164305 ENSG00000179361 ENSG00000136807 ENSG00000150907 ENSG00000164938 ENSG00000151012 ENSG00000148400 ENSG00000137193 ENSG00000127191 ENSG00000140416 ENSG00000114993 ENSG00000142235 ENSG00000106780 ENSG00000100330 ENSG00000054267 ENSG00000258643 ENSG00000175104 ENSG00000096717 ENSG00000184216 PMC4695870__F2 Melanoma cells develop resistance to MAPK inhibitors by mutating (mut) or altering expression of a number of proteins which reactivate MAPK signaling and/or activate alternative survival pathways such as the PI3K pathway ENSG00000167601 ENSG00000019991 ENSG00000157764 ENSG00000171634 ENSG00000187140 ENSG00000066135 ENSG00000146648 ENSG00000196712 PMC6951973__F5 ClueGO pathway enrichment analysis of genes in the yellow module ENSG00000197635 ENSG00000170369 ENSG00000101000 ENSG00000114737 ENSG00000166278 ENSG00000104368 ENSG00000131015 ENSG00000121335 ENSG00000134755 ENSG00000136457 ENSG00000130234 ENSG00000177519 ENSG00000001626 ENSG00000074410 ENSG00000293532 ENSG00000186832 PMC8282197__F6 Identifying Biomarkers from Transcriptomic Signatures in Renal Allograft Biopsies Using Deceased and Living Donors ENSG00000177575 ENSG00000184254 ENSG00000166589 ENSG00000154589 ENSG00000038427 ENSG00000170458 ENSG00000137077 ENSG00000163221 ENSG00000132478 ENSG00000136869 ENSG00000137573 ENSG00000168765 PMC7589702__F7A Resveratrol Rescue Indoxyl Sulfate-Induced Deterioration of Osteoblastogenesis via the Aryl Hydrocarbon Receptor /MAPK Pathway ENSG00000132478 ENSG00000106546 PMC7724827__F2 Interplay between EVA71 infection and autophagy ENSG00000177169 ENSG00000239713 ENSG00000172936 ENSG00000099940 ENSG00000276561 ENSG00000140464 ENSG00000136874 PMC5103287__F1 DGKA and DGKζ in T cell activation and anergy ENSG00000065357 ENSG00000150907 ENSG00000122877 ENSG00000149091 ENSG00000124181 PMC3861040__F5 Parathyroid-Specific Deletion of Klotho Unravels a Novel Calcineurin-Dependent FGF23 Signaling Pathway That Regulates PTH Secretion ENSG00000118972 ENSG00000152266 PMC9256556__F1 TNF in the liver: targeting a central player in inflammation ENSG00000137275 ENSG00000102871 ENSG00000082512 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC7073155__F2 BPA action on placental growth ENSG00000171791 PMC7547615__F1 Pathogenesis and immunomodulation of COVID -19: 1 ENSG00000169245 ENSG00000173992 ENSG00000137033 ENSG00000130234 PMC9256556__F2 TNF in the liver: targeting a central player in inflammation ENSG00000102871 ENSG00000082512 ENSG00000056558 ENSG00000166278 ENSG00000127191 PMC7720688__F3 Biological mechanism of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection ENSG00000130234 ENSG00000125538 ENSG00000184012 PMC1859939__F5 Signal transduction pathways involved in Ha-ras-mediated AEG-1 induction ENSG00000136997 PMC6886443__F5 Proposed model of (defective) AP-3 dependent acquisition of VAMP8 during Weibel-Palade bodies (WPB) maturation ENSG00000110799 ENSG00000135404 ENSG00000118640 PMC7338464__F7 CXCL5 promotes gastric cancer metastasis by inducing epithelial-mesenchymal transition and activating neutrophils ENSG00000170558 ENSG00000145321 PMC4139831__F1 Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000173273 PMC4191885__F5 Reconstruction of the Gene Regulatory Network Involved in the Sonic Hedgehog Pathway with a Potential Role in Early Development of the Mouse Brain ENSG00000107485 ENSG00000164690 PMC5390594__F2 Notch signaling pathways are shown mainly above ENSG00000140968 ENSG00000134070 PMC5390594__F1 AMPK and JNK signaling pathways are shown above ENSG00000125538 ENSG00000096717 PMC8125975__F3 Pediatric Rhabdomyosarcoma: Epidemiology and Genetic Susceptibility ENSG00000157764 ENSG00000115904 ENSG00000108061 ENSG00000196712 ENSG00000179295 PMC5308909__F7 Schematic diagram illustrating the possible interplay between the EGFR and CK2 signaling pathways that regulate GBM cell proliferation ENSG00000105401 ENSG00000168036 ENSG00000146648 PMC8721005__F8 Mfn2 Regulates High Glucose-Induced MAMs Dysfunction and Apoptosis in Podocytes via PERK Pathway ENSG00000128272 ENSG00000116688 PMC8577836__F7 Schematic model of the role of tumor-derived extracellular vesicle (TEV) and CD300a in tumor immunity ENSG00000291918 ENSG00000164342 PMC7291288__F4 ER stress is involved in NLRP3 inflammasome activation ENSG00000162711 ENSG00000125538 ENSG00000162924 PMC8670134__F2 gcMECM: graph clustering of mutual exclusivity of cancer mutations ENSG00000157764 ENSG00000090402 ENSG00000165891 ENSG00000101265 ENSG00000115904 ENSG00000173039 ENSG00000141068 ENSG00000187741 ENSG00000104368 ENSG00000139618 ENSG00000179295 ENSG00000012048 ENSG00000066468 ENSG00000160867 ENSG00000148082 ENSG00000167941 ENSG00000172005 ENSG00000134853 ENSG00000064012 ENSG00000146648 PMC9390238__F6 An Evidence-Based Narrative Review of Mechanisms of Resistance Exercise–Induced Human Skeletal Muscle Hypertrophy ENSG00000198793 ENSG00000151929 PMC4731230__F2 MuSC function are altered in aging ENSG00000135414 ENSG00000168036 ENSG00000168610 PMC5366789__F1 Suggested signaling pathways for induction of the immunosuppressive catabolic enzyme indoleamine 2,3-dioxygenase (IDO1) in vertebrate dendritic cells (DCs) ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC7205985__F7 REGGamma-dependent regulation in ATC dedifferentiation PMC9926763__F8 Sirtuin 3 regulation: a target to alleviate Beta-hydroxybutyric acid-induced mitochondrial dysfunction in bovine granulosa cells ENSG00000177169 ENSG00000198793 ENSG00000142082 ENSG00000026103 PMC4535331__F1 Reflex control of immunity ENSG00000198576 ENSG00000189403 PMC6799818__F5 Additional gut microbial metabolites regulate host immunity and metabolism ENSG00000125538 ENSG00000168036 ENSG00000166090 ENSG00000277641 ENSG00000106546 PMC6412895__F2 Signal transduction pathway of EGFR ENSG00000198793 ENSG00000146648 PMC3989546__F1 Molecular Pathways: Interleukin-15 Signaling in Health and in Cancer ENSG00000033327 ENSG00000105397 ENSG00000088305 ENSG00000136997 ENSG00000113520 ENSG00000105639 ENSG00000168610 PMC6147766__F2 Role of Helicobacter pylori in the reprograming of cellular and molecular programs related to invasive behavior ENSG00000026508 ENSG00000168036 ENSG00000185591 ENSG00000122194 PMC6487278__F4 Schematic model for Cbl-b in BCR- and CD40-mediated signaling pathways Activation of CD40-dependent signaling pathway is mediated primarily by several TNFR-associated factor (TRAF) protein family members including TRAF2, 3, 5, and 6 ENSG00000095585 ENSG00000186716 ENSG00000082512 ENSG00000197943 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000010671 PMC9390238__F2 An Evidence-Based Narrative Review of Mechanisms of Resistance Exercise–Induced Human Skeletal Muscle Hypertrophy ENSG00000177058 ENSG00000167658 ENSG00000151929 ENSG00000239282 PMC8141729__F7 Beta-Asarone Ameliorates Beta-Amyloid–Induced Neurotoxicity in PC12 Cells by Activating P13K/Akt/Nrf2 Signaling Pathway ENSG00000178573 ENSG00000079999 PMC7547615__F3 Mode of action of MSC's for treating COVID-19: 1.Ifusion of MSC's 2 ENSG00000178860 ENSG00000019991 ENSG00000130234 ENSG00000138798 PMC6296341__F1 Two synthesis pathways of fucosylation ENSG00000196968 ENSG00000196371 ENSG00000172728 ENSG00000112699 ENSG00000180549 ENSG00000130383 PMC6428271__F5 Comparative proteomic study reveals the enhanced immune response with the blockade of interleukin 10 with anti-IL-10 and anti-IL-10 receptor antibodies in human U937 cells ENSG00000160789 ENSG00000002330 ENSG00000102871 ENSG00000105401 ENSG00000198793 ENSG00000168040 ENSG00000127191 ENSG00000111348 ENSG00000197694 ENSG00000148935 ENSG00000115317 ENSG00000160049 ENSG00000106683 ENSG00000183735 ENSG00000100813 ENSG00000026103 PMC8274634__F1 Hypothalamic GPCR Signaling Pathways in Cardiometabolic Control ENSG00000198576 ENSG00000116741 PMC3238469__F2 Gene expression changes in cell cycle pathways ENSG00000162889 ENSG00000149311 ENSG00000175054 ENSG00000187741 ENSG00000205089 ENSG00000158169 ENSG00000177084 ENSG00000073756 ENSG00000095002 PMC3547545__F1 An illustration of the IIF pathway genes.Notes: Arrows indicate the direction of signal transduction ENSG00000117020 ENSG00000117525 ENSG00000171105 ENSG00000067992 ENSG00000115457 ENSG00000005882 ENSG00000167779 ENSG00000141753 ENSG00000146678 ENSG00000105647 ENSG00000121879 ENSG00000115461 PMC5516854__F3 Visualizations of Wnt pathway reconstructions ENSG00000004975 ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000291971 ENSG00000170558 ENSG00000149782 ENSG00000168036 ENSG00000101266 ENSG00000135341 ENSG00000121879 ENSG00000125084 ENSG00000196628 ENSG00000157240 ENSG00000170365 ENSG00000163251 ENSG00000001626 ENSG00000177283 ENSG00000155760 ENSG00000101333 ENSG00000138795 ENSG00000107404 ENSG00000148400 ENSG00000182621 ENSG00000137841 ENSG00000071564 ENSG00000104290 ENSG00000075891 ENSG00000161202 ENSG00000146648 PMC6034273__F10 Interaction among MCP-1/CCR2 signaling, TLR4, and GSK3B in ethanol-induced neuroinflammation ENSG00000172936 ENSG00000136869 ENSG00000121807 PMC11865046__F7 TMYXP's key blood components and mechanisms for treating the elderly CHD ENSG00000139193 ENSG00000105329 ENSG00000169429 ENSG00000108443 ENSG00000213341 ENSG00000115232 ENSG00000073756 ENSG00000164305 ENSG00000139687 ENSG00000026103 PMC5507964__F1 TLR7/TLR9 and B cell receptor (BCR) ligands incite B cell signaling cascades ENSG00000153064 ENSG00000110057 ENSG00000168610 ENSG00000276561 ENSG00000010671 ENSG00000095585 ENSG00000100290 ENSG00000239732 ENSG00000186716 ENSG00000197943 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC5336341__F2 Proteomics and tracing experiments reveal the presence of previously unappreciated metabolic pathways in mature RBC.(A) An overview of the central metabolic pathways that are reasonably active in RBC in the light of proteomics evidence ENSG00000284320 ENSG00000131473 ENSG00000100714 ENSG00000213658 ENSG00000173638 ENSG00000172005 ENSG00000118520 ENSG00000146733 ENSG00000116761 ENSG00000102172 PMC10239240__F5 Mettl3 Mediated m6A Methylation Involved in Epithelial-Mesenchymal Transition by Targeting SOCS3/STAT3/SNAI1 in Cigarette Smoking-Induced COPD ENSG00000168610 PMC4958247__F10 Ehrlichia chaffeensis TRP120-mediated activation of canonical Notch signaling pathway and inhibition of TLR2/4 expression ENSG00000148400 ENSG00000136869 PMC8848293__F2 Maintenance of protein homeostasis in glia extends lifespan in C. elegans ENSG00000128272 ENSG00000100219 PMC8085043__F1 Current Concepts and Advances in Graft-Versus-Host Disease Immunology ENSG00000163599 ENSG00000118520 ENSG00000026103 PMC3293584__F1 Schematic of folate-mediated one-carbon metabolism in the cytoplasm and nucleus ENSG00000284320 ENSG00000228716 PMC10854459__F8 Anticancer role of JAC in AGS cells ENSG00000154342 ENSG00000002330 ENSG00000135446 ENSG00000170558 ENSG00000168036 ENSG00000123374 ENSG00000105810 ENSG00000168610 PMC8458965__F2 MAVS: A Two-Sided CARD Mediating Antiviral Innate Immune Signaling and Regulating Immune Homeostasis ENSG00000087095 ENSG00000132109 ENSG00000183735 ENSG00000088888 ENSG00000147162 ENSG00000165312 ENSG00000160703 ENSG00000170633 ENSG00000121060 ENSG00000101695 ENSG00000185104 PMC7461825__F1 Role CRP on the innate immune system and tumor progression ENSG00000198793 ENSG00000132693 PMC7565831__F3 Amino acid sensing by mTORC1 ENSG00000177058 ENSG00000143761 ENSG00000239282 PMC7906923__F1 Molecular signaling pathways implicated in neuroblastoma ENSG00000198793 ENSG00000168036 ENSG00000146648 ENSG00000157240 PMC2890581__F7 Inflammatory Mediator TAK1 Regulates Hair Follicle Morphogenesis and Anagen Induction Shown by Using Keratinocyte-Specific TAK1-Deficient Mice ENSG00000186197 ENSG00000135960 ENSG00000168036 ENSG00000175104 PMC9048116__F7 Autotaxin signaling facilitates B cell dedifferentiation and dysfunction induced by Sirtuin 3 deficiency ENSG00000136960 ENSG00000198670 ENSG00000142082 PMC6336527__F2 UV-induced cutaneous tanning response ENSG00000173599 ENSG00000115138 ENSG00000080166 ENSG00000107165 PMC8712140__F13 To Predict Anti-Inflammatory and Immunomodulatory Targets of Guizhi Decoction in Treating Asthma Based on Network Pharmacology, Molecular Docking, and Experimental Validation ENSG00000104365 ENSG00000117020 ENSG00000100906 ENSG00000109320 ENSG00000269335 ENSG00000173039 ENSG00000184371 ENSG00000213341 ENSG00000169032 ENSG00000006062 ENSG00000135341 ENSG00000146648 PMC1617297__F2 Cell-signaling networks induced by Pichinde virus infection as analyzed using the Ingenuity pathway analysis knowledge base ENSG00000104884 ENSG00000173039 ENSG00000122877 ENSG00000035928 ENSG00000182621 ENSG00000189283 ENSG00000112242 ENSG00000110395 ENSG00000082175 ENSG00000078900 ENSG00000163558 ENSG00000136997 ENSG00000204843 ENSG00000164362 ENSG00000163848 ENSG00000151617 ENSG00000283060 ENSG00000143196 ENSG00000139687 ENSG00000282899 ENSG00000136936 PMC6053276__F1 A simplified representation of the HIPPO pathway ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC6492170__F1 Schematic representation of iron metabolism in the yeast model ENSG00000153815 ENSG00000182511 PMC7445288__F6 Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate ENSG00000157764 ENSG00000065361 ENSG00000134982 ENSG00000065559 ENSG00000164985 ENSG00000135373 ENSG00000146374 ENSG00000149311 ENSG00000163435 ENSG00000108375 ENSG00000139687 ENSG00000196712 ENSG00000189079 ENSG00000109670 PMC8198587__F3 Circular RNAs: Emerging Regulators of the Major Signaling Pathways Involved in Cancer Progression ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000172977 ENSG00000175792 PMC8458965__F3 MAVS: A Two-Sided CARD Mediating Antiviral Innate Immune Signaling and Regulating Immune Homeostasis ENSG00000180210 ENSG00000183735 ENSG00000088888 ENSG00000160703 ENSG00000102471 PMC12014800__F2 Value-added products derived from fatty acids and derivatives, which can be synthesized by yeast cell factories with tuned fatty acid profiles ENSG00000099864 ENSG00000026103 PMC9367355__F5 The Cancer Stem Phenotype by Long Non-Coding RNAs PMC9367355__F4 The Cancer Stem Phenotype by Long Non-Coding RNAs ENSG00000215021 ENSG00000168036 PMC10559995__F1 Signaling Pathway of Estrogen Receptor ENSG00000138798 ENSG00000146648 PMC10559995__F3 Estrogen metabolism pathway in humans PMC5866458__F1 A change of view: homologous recombination at single-molecule resolution ENSG00000051180 ENSG00000100206 ENSG00000138385 PMC7731470__F4 Illustration of the effects of polycystins dysfunctioning on EGFR and MAPK/ERK pathway ENSG00000138798 ENSG00000146648 PMC8353397__F9 Antiatherogenic Effects of Quercetin in the THP-1 Macrophage Model In Vitro, With Insights Into Its Signaling Mechanisms Using In Silico Analysis ENSG00000177606 ENSG00000121966 ENSG00000135517 PMC7922523__F4 TGFB/EMT signalling in pSS PMC6316148__F2 Relationship between mechanical loading and sclerostin expression ENSG00000281324 ENSG00000162337 ENSG00000167941 PMC10552500__F3 Nutraceutical-mediated signaling pathways underlying some neuroprotective processes ENSG00000142192 ENSG00000137845 PMC9367355__F3 The Cancer Stem Phenotype by Long Non-Coding RNAs ENSG00000026508 ENSG00000100211 PMC11827473__F6 Anti-tumor effects of ArcA on the aggressive behavior of metastatic melanoma cells ENSG00000135446 ENSG00000100985 PMC8261167__F2 Emerging mechanisms and targeted therapy of ferroptosis in cancer ENSG00000196839 ENSG00000167468 ENSG00000113161 ENSG00000111684 ENSG00000127948 ENSG00000136381 ENSG00000079999 PMC8261167__F1 Emerging mechanisms and targeted therapy of ferroptosis in cancer ENSG00000168003 ENSG00000163930 ENSG00000151012 ENSG00000167468 ENSG00000111371 ENSG00000162772 ENSG00000116761 ENSG00000115419 PMC5492138__F5 Mechanism of encoding the NSC modules ENSG00000291507 ENSG00000115263 ENSG00000115271 PMC8261167__F4 Emerging mechanisms and targeted therapy of ferroptosis in cancer ENSG00000168003 ENSG00000111537 ENSG00000151012 ENSG00000105329 ENSG00000167468 ENSG00000189403 ENSG00000118520 ENSG00000168610 PMC2263022__F6 Superposition of 'omics' data on maps ENSG00000117724 ENSG00000149311 ENSG00000138778 ENSG00000115163 ENSG00000134982 ENSG00000132646 ENSG00000112742 ENSG00000076604 PMC6695732__F6 Model of ESRP1-mediated cell cycle G1-phase arrest ENSG00000104413 ENSG00000145386 ENSG00000117399 PMC7322029__F7 Cartoon comparing canonical Hippo signaling with signaling by Legionella LegK7 ENSG00000131023 PMC7793796__F5 CAM-DR in leukemia ENSG00000026508 ENSG00000168036 ENSG00000162692 PMC5713154__F4 Cell signaling pathway scheme of metabolic alterations due to Zika virus infection ENSG00000064601 ENSG00000196549 ENSG00000130234 ENSG00000198793 ENSG00000115020 ENSG00000163751 PMC8424139__F5 Diagram depicts the regulation of retinoid metabolism by PI3K-AKT pathway in RPE ENSG00000135437 ENSG00000121207 ENSG00000116745 ENSG00000197713 ENSG00000121039 ENSG00000196344 ENSG00000080511 PMC3761196__F8 This figure depicts a model of the lipid synthesis genes in the human mammary epithelial cell during secretory activation according to cell compartment ENSG00000131473 ENSG00000042832 ENSG00000152642 ENSG00000151365 ENSG00000186480 ENSG00000169710 ENSG00000175066 ENSG00000076555 ENSG00000158125 ENSG00000073060 ENSG00000138135 ENSG00000134324 ENSG00000285482 ENSG00000160179 ENSG00000005187 PMC3761196__F7 Cell compartment view for network of lipid metabolic genes highlighting the role of SREBF1, THRSP, and ESRRA curated by ingenuity pathway analysis (IPA) ENSG00000131473 ENSG00000151726 ENSG00000135218 ENSG00000112972 ENSG00000108786 ENSG00000172893 ENSG00000117118 ENSG00000113161 ENSG00000169710 ENSG00000076555 ENSG00000167508 ENSG00000132170 ENSG00000160752 ENSG00000067064 ENSG00000117054 ENSG00000073060 ENSG00000170522 ENSG00000107537 ENSG00000134824 ENSG00000161533 ENSG00000104549 ENSG00000113790 ENSG00000198911 PMC11353167__F2 MAPK signaling pathway ENSG00000070831 ENSG00000130522 ENSG00000163914 PMC7999830__F7 The proposed model ENSG00000116044 ENSG00000125538 PMC11353167__F1 FCERI signaling pathway ENSG00000033327 ENSG00000213658 ENSG00000010810 PMC6065096__F8 R431C mutation induces hyperproliferation, hypermotility and ER stress-induced apoptosis in podocytes ENSG00000198793 ENSG00000198087 PMC3282414__F2 Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities ENSG00000005882 ENSG00000198793 ENSG00000198576 ENSG00000162105 ENSG00000292254 ENSG00000196712 PMC7022340__F6 Working model of the roles of Beta-catenin and US3 in the DNA-sensing signaling pathway ENSG00000183735 ENSG00000164430 ENSG00000134982 ENSG00000168036 PMC11313500__F2 Molecular pathway mechanisms of cytokines and chemokines associated with inflammation for the progression of pulmonary hypertension ENSG00000172936 PMC6921378__F5 Molecular models of the potential role of proteins involved in the Nrf2 – mediated response to NCC exposure ENSG00000128272 ENSG00000134982 PMC3761885__F2 Proposed regulation of cardiac Per2 ENSG00000100387 ENSG00000113558 ENSG00000132326 ENSG00000285246 ENSG00000170425 ENSG00000146648 PMC9489100__F2 Lung involvement in monogenic interferonopathies ENSG00000213928 ENSG00000187608 ENSG00000122218 ENSG00000102575 ENSG00000151092 ENSG00000142166 ENSG00000184979 ENSG00000149311 ENSG00000183735 ENSG00000105612 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000093072 ENSG00000132963 PMC6076434__F8 Schematic view of pathways regulating IL-1A expression in hRPE cells ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000276561 PMC3283716__F1 Novel Classification of Lung Cancer into Molecular Subtypes ENSG00000002330 ENSG00000198793 ENSG00000171791 PMC5331196__F1 Sensing infection and tissue damage ENSG00000213928 ENSG00000088888 ENSG00000115415 PMC5580489__F3 Host DNA damage response pathways ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000144554 ENSG00000187741 ENSG00000139618 PMC7471766__F3 Classic and trans-signaling IL-6R ENSG00000168610 PMC10551140__F7 Sestrin2 protects against hypoxic nerve injury by regulating mitophagy through SESN2/AMPK pathway ENSG00000198793 ENSG00000160703 PMC4339430__F6 Proposed role of CCL21/CCR7 axis in lymphangiogenesis ENSG00000137077 ENSG00000126353 ENSG00000121807 ENSG00000150630 PMC7497240__F2 A) Comparison of the putative biosynthetic gene cluster (BGC) of tjipanazole biosynthesis in F ENSG00000277401 PMC8542988__F3 Shedding Light on Microbial “Dark Matter”: Insights Into Novel Cloacimonadota and Omnitrophota From an Antarctic Lake ENSG00000132341 PMC2900152__F9 Proposed DAP12 signaling pathway in macrophages and osteoclasts ENSG00000134215 PMC7907466__F1 Complement Cascade in HIE ENSG00000039537 ENSG00000113600 ENSG00000166278 PMC4474341__F1 Biochemical pathways ENSG00000171444 ENSG00000128928 PMC8466551__F1 Smoothened-Dependent and -Independent Hedgehog Signaling Pathway in Tumorigenesis ENSG00000143147 ENSG00000128602 PMC3913970__F1 BCR/BTK signaling pathway ENSG00000186716 ENSG00000198793 ENSG00000010671 PMC8466551__F3 Smoothened-Dependent and -Independent Hedgehog Signaling Pathway in Tumorigenesis ENSG00000087245 ENSG00000169554 ENSG00000170558 ENSG00000171791 ENSG00000112715 ENSG00000118971 ENSG00000118777 ENSG00000108691 ENSG00000124216 ENSG00000125398 ENSG00000157227 ENSG00000149968 ENSG00000122691 ENSG00000100985 ENSG00000118257 PMC3679383__F1 Pathways of GPL biosynthesis in eukaryotic cells: temporal regulation of GPL-synthesizing enzyme activities ENSG00000105894 ENSG00000173599 ENSG00000198670 ENSG00000184207 ENSG00000133027 PMC8466551__F6 Smoothened-Dependent and -Independent Hedgehog Signaling Pathway in Tumorigenesis ENSG00000281324 ENSG00000162337 ENSG00000198793 ENSG00000168036 ENSG00000164690 ENSG00000112715 ENSG00000118257 PMC2642659__F2 Visualization of molecular interaction and reaction networks in the KEGG database ENSG00000087095 ENSG00000159224 ENSG00000171105 ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000134982 ENSG00000291971 ENSG00000140575 ENSG00000168036 ENSG00000196470 ENSG00000115718 ENSG00000100592 ENSG00000100387 ENSG00000147869 ENSG00000113558 ENSG00000136153 ENSG00000077782 ENSG00000140443 PMC8466551__F5 Smoothened-Dependent and -Independent Hedgehog Signaling Pathway in Tumorigenesis ENSG00000185591 ENSG00000164690 ENSG00000128602 PMC5785435__F2 Bevacizumab-Induced Hypertension: Clinical Presentation and Molecular Understanding ENSG00000132906 ENSG00000142192 ENSG00000002330 PMC5564072__F5 T cell receptor (TCR) signaling pathway in melanoma (modified from the BioCarta database) ENSG00000291603 ENSG00000213658 ENSG00000010810 PMC8965842__F4 MiR-223 as a Regulator and Therapeutic Target in Liver Diseases ENSG00000169245 ENSG00000162711 ENSG00000081041 ENSG00000130164 ENSG00000009844 ENSG00000168610 PMC11930265__F9 LTA promotes aerobic glycolysis (AG) and M1 polarization in macrophages by activating the NFKB signaling pathway ENSG00000226275 ENSG00000002330 ENSG00000159399 PMC3959571__F1 Q6 biosynthesis in S ENSG00000132423 ENSG00000167113 ENSG00000039537 ENSG00000110871 ENSG00000088682 ENSG00000164597 ENSG00000173085 ENSG00000167186 PMC3711327__F7 A model for the regulation of transcriptional induction of ICL1 and FBP1 by the PIPTC ENSG00000124102 PMC5943571__F1 Pathway for glycosphingolipids (GSLs) biosynthesis PMC11049046__F6 KEGG pathway of the PI3K-Akt signaling pathway with target genes of our known miRNAs shown in red stars and targets of novel miRNA NC_060925 ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000104894 PMC11049046__F5 KEGG pathway of the MAPK signaling pathway with target genes of our known miRNAs shown in red stars and targets of novel miRNA NC_060925 ENSG00000087095 ENSG00000170458 ENSG00000102871 ENSG00000138798 ENSG00000130159 ENSG00000127191 ENSG00000081189 ENSG00000010671 ENSG00000026103 PMC4550685__F1 Intracellular pathways of factors regulating adipogenesis, lipogenesis and lipolysis in the adipocyte ENSG00000171105 ENSG00000042832 ENSG00000004455 ENSG00000145321 ENSG00000168610 ENSG00000026103 PMC7646947__F3 Receptors and substances involved in metabolism that affect muscle protein synthesis and degradation in cancer cachexia PMC7646947__F1 Molecules and signaling pathways involved in muscle protein synthesis and degradation ENSG00000198793 ENSG00000168610 ENSG00000140443 PMC8018731__F11 NOX1/NADPH Oxidase Promotes Synaptic Facilitation Induced by Repeated D2 Receptor Stimulation: Involvement in Behavioral Repetition ENSG00000291971 ENSG00000062485 PMC7851083__F1 Important events during research development of macropinocytosis in cancers ENSG00000070831 ENSG00000099864 PMC8466551__F7 Smoothened-Dependent and -Independent Hedgehog Signaling Pathway in Tumorigenesis ENSG00000125398 ENSG00000113558 ENSG00000184634 ENSG00000121067 ENSG00000140443 PMC3031870__F1 MTORC1 and mTORC2 signaling branches PMC3335081__F9 Resveratrol Mediated Modulation of Sirt-1/Runx2 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells: Potential Role of Runx2 Deacetylation ENSG00000178860 ENSG00000096717 PMC7851083__F3 Mechanism of extracellular proteins internalization through macropinocytosis ENSG00000128272 ENSG00000146648 PMC3285217__F1 Drosophila signaling pathways that regulate humoral responses ENSG00000112977 ENSG00000172936 ENSG00000168040 PMC3331679__F2 mTOR signaling in growth control and disease ENSG00000100811 ENSG00000177169 ENSG00000011566 ENSG00000163914 ENSG00000284161 ENSG00000118515 ENSG00000167658 ENSG00000179632 ENSG00000196712 ENSG00000151151 PMC4149926__F1 Cytomegalovirus microRNAs ENSG00000185883 ENSG00000185515 ENSG00000166974 ENSG00000070831 ENSG00000103769 ENSG00000231179 ENSG00000174059 ENSG00000108774 ENSG00000255302 ENSG00000175305 PMC9308931__F8 Unveiling of brain transcriptome of masked palm civet (Paguma larvata) with chronic infection of Toxoplasma gondii ENSG00000174125 ENSG00000239732 ENSG00000140968 ENSG00000172936 ENSG00000136869 ENSG00000185187 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000010671 ENSG00000164342 PMC7984366__F2 Endogenous estrogen regulates the proliferation and differentiation of NSPCs ENSG00000291971 ENSG00000146648 PMC7984366__F3 Estrogen-like molecules activate the classical estrogen signaling cascade and alternative pathways ENSG00000168036 ENSG00000096717 PMC5332937__F1 Canonical WNT signaling pathway ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000105723 PMC10297136__F3 Signal pathways associated with lung adenocarcinoma ENSG00000149311 ENSG00000134982 ENSG00000198793 ENSG00000146648 ENSG00000196712 PMC6743980__F2 Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics ENSG00000163914 ENSG00000146648 ENSG00000122194 PMC8692119__F1 Novel contributors to B cell activation during inflammatory CNS demyelination; An oNGOing process ENSG00000177455 ENSG00000104856 ENSG00000186716 ENSG00000198793 ENSG00000173039 ENSG00000127191 PMC5759931__F6 Proposed working model by which boehmenan exerted anti-proliferative activities in A431 cells ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC8085043__F2 Current Concepts and Advances in Graft-Versus-Host Disease Immunology ENSG00000182578 ENSG00000145321 ENSG00000184371 ENSG00000103522 ENSG00000168610 ENSG00000010671 PMC10297136__F5 Glioblastoma multiforme (GBM)-related signal pathways ENSG00000135446 ENSG00000198793 ENSG00000146648 ENSG00000139687 ENSG00000196712 PMC11700987__F2 Staphylococcus aureus prevents Nrf2 pathway activation in THP-1 macrophages through upregulation of MAPK/p38 and downregulation of p62/SQTM1, scheme modified from [35] ENSG00000108691 ENSG00000079999 PMC11700987__F1 NRF2/KEAP1 signaling pathway adapted from [17] ENSG00000181019 ENSG00000100387 ENSG00000023909 ENSG00000079999 PMC11700987__F6 Keap1/Nrf2 signaling pathway plays a crucial role in the cellular response to P ENSG00000198830 ENSG00000163235 ENSG00000113070 ENSG00000146648 ENSG00000079999 PMC11700987__F4 Listeria monocytogenes evades the host immune response by Tim-3-dependent inhibition of the Keap1/Nrf2 signaling pathway ENSG00000135218 ENSG00000079999 PMC9592927__F3 Emerging role of circular RNAs in drug resistance of non-small cell lung cancer ENSG00000102349 ENSG00000168036 ENSG00000168610 ENSG00000146648 ENSG00000147689 PMC11700987__F3 Activation of Nrf2 in S ENSG00000175793 ENSG00000178573 ENSG00000079999 PMC7272282__F1 PI3K pathway ENSG00000124102 ENSG00000109452 PMC4367834__F5 Dopamine biosynthesis and degradation and the genes coding key enzymes ENSG00000072210 ENSG00000123454 ENSG00000141744 ENSG00000171759 ENSG00000085662 PMC6770301__F2 Regulation of EMT at different molecular levels: upregulation of the WNT pathway, PI3K/AKT pathway, and RAS/RAF/MEK/ERK/MAPK pathway and downregulation of the TGFB/Smad pathway lead to the activation of EMT through downregulation of E-cadherin ENSG00000176692 ENSG00000134982 ENSG00000185669 ENSG00000125538 ENSG00000168036 ENSG00000168610 ENSG00000196628 PMC7272282__F3 Crosstalk between PI3K signaling and DNA damage repair pathways ENSG00000149311 ENSG00000012048 ENSG00000144554 ENSG00000158636 ENSG00000051180 ENSG00000108106 ENSG00000139618 PMC7272282__F2 Cell cycle checkpoints ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000138385 PMC4626177__F6 Pathway network analyses of upregulated genes from early stage (stages II and IIIa) TNBC ENSG00000164761 ENSG00000169862 ENSG00000115415 ENSG00000115457 ENSG00000167754 ENSG00000170558 ENSG00000120885 PMC4626177__F7 Pathway network analyses on upregulated genes from late stage (stage IIIc) TNBC ENSG00000124216 ENSG00000138795 ENSG00000169213 ENSG00000120149 ENSG00000138798 ENSG00000075891 ENSG00000132639 PMC3928651__F2 Solving Glycosylation Disorders: Fundamental Approaches Reveal Complicated Pathways ENSG00000101901 ENSG00000000419 ENSG00000134910 ENSG00000033011 ENSG00000104723 ENSG00000173540 ENSG00000163463 ENSG00000086848 ENSG00000244038 ENSG00000139133 ENSG00000102158 ENSG00000159063 ENSG00000163933 ENSG00000163527 ENSG00000214160 ENSG00000136908 ENSG00000182858 PMC9592927__F2 Emerging role of circular RNAs in drug resistance of non-small cell lung cancer ENSG00000168610 ENSG00000146648 PMC5578163__F1 Physiology of the VHL-HIF pathway along with proposed etiopathogenesis that leads to metastatic ccRCC ENSG00000168283 ENSG00000134086 ENSG00000122691 ENSG00000198793 ENSG00000126353 ENSG00000164690 ENSG00000146648 ENSG00000121966 PMC4775036__F5 Main canonical pathways induced by cigarette smoke extract ENSG00000122025 ENSG00000242689 ENSG00000168036 PMC1609106__F8 Regulation of insulin pathway phenotypes by AKT-1 and PDK-1 activation PMC6059118__F1 USE1 is a critical ubiquitin-conjugating enzyme in lung cancer cells ENSG00000033178 ENSG00000053501 ENSG00000117152 PMC11539471__F2 Mechanisms of action of clinically studied CAR-T targets in gliomas ENSG00000142627 ENSG00000123496 ENSG00000198793 ENSG00000112715 ENSG00000168610 PMC7845757__F7 Mechanisms underlying DAC-paracetamol interaction ENSG00000130649 PMC7177421__F1 Receptor 4 (TLR4) general signalling transduction pathway ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC8869442__F2 Targeting the Ubiquitylation and ISGylation Machinery for the Treatment of COVID-19 ENSG00000184979 ENSG00000135655 ENSG00000088888 ENSG00000187608 ENSG00000136869 ENSG00000083799 ENSG00000121060 ENSG00000276561 ENSG00000277276 PMC7105732__F1 “Four Hits” Hypothesis of IgA Nephropathy ENSG00000239732 ENSG00000136869 PMC3558870__F1 The potential disruption of hepatic GH signaling pathways by MC ENSG00000112964 ENSG00000169047 PMC7522543__F6 The prostate cancer pathway ENSG00000157554 ENSG00000002330 ENSG00000198793 ENSG00000115904 ENSG00000168036 ENSG00000171791 ENSG00000169032 ENSG00000100485 ENSG00000121879 ENSG00000124762 ENSG00000104368 ENSG00000145431 ENSG00000112242 ENSG00000244405 ENSG00000277893 ENSG00000150907 ENSG00000184012 ENSG00000077782 ENSG00000139687 ENSG00000282899 ENSG00000132906 ENSG00000124102 ENSG00000104365 ENSG00000005339 ENSG00000157764 ENSG00000182158 ENSG00000100906 ENSG00000109320 ENSG00000292149 ENSG00000269335 ENSG00000173039 ENSG00000213341 ENSG00000107175 ENSG00000167034 ENSG00000197461 ENSG00000066468 ENSG00000117020 ENSG00000128272 ENSG00000170962 ENSG00000163235 ENSG00000134853 ENSG00000100985 ENSG00000171608 ENSG00000146648 ENSG00000175305 PMC4362880__F1 Beta-amyloid precursor protein (BAPP) processing in Alzheimer’s disease (AD) and age-related macular degeneration (AMD) ENSG00000011600 ENSG00000106025 ENSG00000137845 PMC3808429__F7 Prediction of Oncogenic Interactions and Cancer-Related Signaling Networks Based on Network Topology ENSG00000291971 ENSG00000168036 ENSG00000112715 ENSG00000124181 ENSG00000168610 ENSG00000146648 ENSG00000160691 PMC3808429__F6 Prediction of Oncogenic Interactions and Cancer-Related Signaling Networks Based on Network Topology ENSG00000100906 ENSG00000109320 ENSG00000168036 ENSG00000213341 ENSG00000146648 PMC2665046__F3 Multivalency-Assisted Control of Intracellular Signaling Pathways: Application for Ubiquitin-Dependent N-End Rule Pathway ENSG00000157045 ENSG00000107669 PMC7051146__F1 Pro-viral roles of autophagy during virus infection ENSG00000177169 ENSG00000088888 ENSG00000198793 ENSG00000145782 PMC7969890__F1 Elements of the classical and alternative complement pathways, separated by the unique and common aspects ENSG00000166278 ENSG00000236625 PMC4276135__F2 Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signalling ENSG00000095585 ENSG00000166349 ENSG00000112576 ENSG00000137265 ENSG00000283060 ENSG00000175097 ENSG00000168685 PMC4682379__F4 Transcription_P53 signaling pathway ENSG00000149311 ENSG00000175054 ENSG00000033800 ENSG00000153201 ENSG00000168036 ENSG00000139372 ENSG00000116030 ENSG00000112715 ENSG00000047849 ENSG00000136936 ENSG00000149480 PMC7676935__F2 Summary of the possible signaling pathway between gut microbiota-bile acids axis and IBS-D PMC5053351__F7 The Pga1-mediated signal transduction pathway, showing the effectors AC and PKA previously reported in different fungi, along with newly identified effectors and proteins and their relation with the cellular processes regulated by Pga1 ENSG00000167900 ENSG00000132341 PMC3499368__F1 Evolution of Minimal Specificity and Promiscuity in Steroid Hormone Receptors PMC6013028__F2 Direct effects of thyroid hormones on hepatic lipid metabolism ENSG00000138075 ENSG00000165556 ENSG00000160752 ENSG00000130164 ENSG00000167910 ENSG00000113161 ENSG00000167780 ENSG00000143921 PMC7199749__F1 Genomic stabilization by TTK ENSG00000137812 ENSG00000112742 PMC8453015__F3 Function of Protein S-Palmitoylation in Immunity and Immune-Related Diseases ENSG00000183735 ENSG00000164430 PMC4452497__F9 UVB Stimulates the Expression of Endothelin B Receptor in Human Melanocytes via a Sequential Activation of the p38/MSK1/CREB/MITF Pathway Which Can Be Interrupted by a French Maritime Pine Bark Extract through a Direct Inactivation of MSK1 ENSG00000136160 PMC11477111__F6 Regulatory role of FMR1/FMRP on BMPR2 in granulosa cells ENSG00000164404 ENSG00000130385 ENSG00000102081 ENSG00000204217 PMC5915462__F1 Pathways of deoxyribonucleotide metabolism in mammalian cells ENSG00000102967 PMC11667896__F2 GLP-1 (glucagon-like peptide-1) plays a vital role in neuroprotection and regeneration through multiple mechanisms ENSG00000132906 ENSG00000164305 ENSG00000106459 PMC3519947__F1 Simplified diagram illustrating the mTOR signaling pathway ENSG00000198793 PMC9122672__F1 Bile Acids and Nuclear Receptors in Acupuncture in Improving Crohn's Disease ENSG00000167910 ENSG00000180432 ENSG00000099377 ENSG00000135929 PMC4395138__F1 Extrinsic and intrinsic pathways of apoptosis ENSG00000142192 ENSG00000168040 ENSG00000026103 PMC2736107__F2 In addition to the hypothesis outlined in , a number of other mechanistic pathways could potentially lead to the formation of products 3-5 () ENSG00000004848 PMC7590567__F1 Viral Infections: Negative Regulators of Apoptosis and Oncogenic Factors ENSG00000100290 ENSG00000002330 ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000135116 ENSG00000104081 PMC5143325__F1 Reactions induced by oxytocin ENSG00000187688 ENSG00000175206 ENSG00000162551 ENSG00000198793 ENSG00000173039 ENSG00000110013 ENSG00000213341 ENSG00000137055 ENSG00000113441 PMC2610675__F6 Arrestin-3 is essential for the activation of Fyn by the luteinizing hormone receptor (LHR) in MA-10 cells ENSG00000120500 ENSG00000010810 ENSG00000146648 PMC6616656__F2 Long non-coding RNA acting within the NODAL signalling pathway ENSG00000160973 ENSG00000143768 ENSG00000243709 ENSG00000156574 ENSG00000179284 ENSG00000164093 PMC5817857__F2 An RTK and the downstream PI3K/AKT pathway ENSG00000198793 ENSG00000155792 ENSG00000164327 PMC9574935__F1 SARS-CoV-2 accessory proteins in immune evasion ENSG00000088888 ENSG00000121060 PMC2939266__F3 Dopamine-sensitive signaling via adenylyl cyclase (AC), phospholipase C (PLC), and phosphatidylinositol-3-kinase (PI3K) systems ENSG00000198793 ENSG00000149295 PMC114459__F1 Mechanisms of ISG induction ENSG00000105397 ENSG00000115415 PMC3044944__F6 Hypothetic model for TGF-Beta-regulated KLF4 proteolysis ENSG00000134982 ENSG00000136826 PMC5386709__F7 Identification of downstream metastasis-associated target genes regulated by LSD1 in colon cancer cells ENSG00000175054 ENSG00000030582 PMC4272576__F2 Candidate genes influenced by Zn2+ or involved in Zn2+signaling and metal ion homeostasis associated with the development of ASDs ENSG00000188786 ENSG00000173163 ENSG00000162105 ENSG00000292254 PMC5577170__F7 Schematic representing the key role of IFNA and LPS-activated monocyte-derived exosomes in brain endothelial stimulation ENSG00000105894 ENSG00000108691 ENSG00000125538 ENSG00000136869 ENSG00000162692 PMC7587305__F3 XRCC1 participates in BER by facilitating transfer of DNA damage ENSG00000143799 PMC9529500__F3 Effectiveness and Mechanisms of Low-Intensity Pulsed Ultrasound on Osseointegration of Dental Implants and Biological Functions of Bone Marrow Mesenchymal Stem Cells ENSG00000170365 ENSG00000134982 ENSG00000173156 ENSG00000120693 ENSG00000168036 ENSG00000164690 ENSG00000128602 ENSG00000204217 ENSG00000121966 PMC6099164__F2 Transforming growth factor‐B (TGF‐B) promotes T helper 17 (Th17) differentiation through multiple mechanisms ENSG00000134460 ENSG00000159216 ENSG00000163235 ENSG00000137265 ENSG00000103522 ENSG00000049768 ENSG00000168610 PMC9098327__F4 Cross-Talk between Polyphenols and the Target Enzymes Related to Oxidative Stress-Induced Thyroid Cancer ENSG00000181019 ENSG00000178573 ENSG00000100387 ENSG00000106546 PMC8080601__F3 Processing, extracellular regulation, and signaling mechanisms of GDF11 and MSTN ENSG00000121989 ENSG00000170365 ENSG00000120693 ENSG00000070404 ENSG00000135414 ENSG00000168487 PMC3541634__F1 Schematic of TGFB1 signaling pathway and its regulation ENSG00000198742 PMC8468667__F7 MicroRNA-Based Risk Score for Predicting Tumor Progression Following Radioactive Iodine Ablation in Well-Differentiated Thyroid Cancer Patients: A Propensity-Score Matched Analysis ENSG00000112242 ENSG00000136997 ENSG00000100697 ENSG00000171791 ENSG00000096717 ENSG00000123908 PMC7587305__F5 XRCC1-APLF – an interaction between two DNA scaffolds ENSG00000169621 ENSG00000039650 ENSG00000137074 PMC2800820__F1 Multiple pro-inflammatory mediators in the tumor microenvironment increase the accumulation of MDS cells and enhance their immunosuppressive activity ENSG00000125538 PMC6011883__F2 Complexes formed by mutant p53 and their roles in breast cancer ENSG00000079387 ENSG00000171105 ENSG00000136848 PMC8230471__F8 Sustained Release of Insulin-Like Growth Factor-1 from Bombyx mori L. Silk Fibroin Delivery for Diabetic Wound Therapy ENSG00000002330 ENSG00000138798 ENSG00000169047 ENSG00000198793 PMC3518431__F2 Autophagy modulation as a potential therapeutic target for diverse diseases ENSG00000124102 ENSG00000177169 ENSG00000188554 PMC10299133__F1 HGF/MET signaling pathway and most frequent alterations in NSCLC ENSG00000019991 ENSG00000168610 PMC3518431__F1 Autophagy modulation as a potential therapeutic target for diverse diseases ENSG00000177169 ENSG00000171105 ENSG00000112561 ENSG00000181467 PMC2841835__F1 Host defence signaling pathways in Caenorhabditis elegans model ENSG00000129167 ENSG00000118515 PMC7028286__F5 Top two modules from the PPI interaction networks ENSG00000142192 ENSG00000072274 ENSG00000110651 ENSG00000010278 ENSG00000135404 ENSG00000106688 ENSG00000115419 ENSG00000159399 PMC5415012__F1 Schematic representations of selected modes of cross-talk between autophagy and the secretory pathway ENSG00000177169 ENSG00000196663 ENSG00000083290 ENSG00000148396 PMC8709197__F7 Global Metabolic Map Defines the Effects of a Si-Based Biostimulant on Tomato Plants under Normal and Saline Conditions ENSG00000090402 ENSG00000185129 PMC7662679__F1 Monoclonal antibodies: types and mechanisms of action PMC4721243__F4 DDN, (b) GDNPN, and (c) GDNnon-PN of PI3K events in ERBB2 signaling (M570) pathway ENSG00000132906 ENSG00000002330 ENSG00000065361 ENSG00000138798 ENSG00000113070 ENSG00000158458 ENSG00000164327 ENSG00000181418 ENSG00000213341 ENSG00000121879 ENSG00000184481 ENSG00000124762 ENSG00000175634 ENSG00000117020 ENSG00000124882 ENSG00000146648 ENSG00000105723 ENSG00000178568 PMC4721243__F3 DDN, (b) GDNMES, and (c) GDNnon-MES of Integrin AIIb B3 signaling (M760) pathway ENSG00000140992 ENSG00000259207 ENSG00000291971 ENSG00000077420 ENSG00000115904 ENSG00000137076 ENSG00000181418 ENSG00000196396 ENSG00000171560 ENSG00000160691 PMC3446651__F2 Viral proteins inhibit nucleic acid receptors of the intracytosolic innate immune response ENSG00000039537 ENSG00000183735 ENSG00000088888 ENSG00000175104 PMC11676821__F3 Action of PAK2 in the regulation of different signaling pathways in different cancers ENSG00000167258 ENSG00000198793 ENSG00000185591 ENSG00000166508 ENSG00000136874 PMC7418434__F1 Pathways controlling ferroptosis, necroptosis, and pyroptosis ENSG00000162711 ENSG00000137275 ENSG00000167468 ENSG00000168404 ENSG00000285379 PMC6959074__F3 Roles of sirtuins may be involved in nicotine/nAChR-mediated signaling pathway ENSG00000117971 ENSG00000187531 ENSG00000124523 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000089163 ENSG00000283100 ENSG00000080644 PMC6959074__F2 nAChR-mediated signaling pathways that lead to lung cancer progression ENSG00000102145 ENSG00000162711 ENSG00000291971 ENSG00000138798 ENSG00000172936 ENSG00000185591 ENSG00000168610 ENSG00000146648 PMC9368800__F1 Delivery of Nucleotide Sugars to the Mammalian Golgi: A Very Well (un)Explained Story ENSG00000164414 ENSG00000205060 ENSG00000117620 ENSG00000292209 PMC12128733__F14 Effect of Withania extracts in two doses on the eicosanoid signaling pathway ENSG00000108839 ENSG00000161905 ENSG00000122420 PMC4498740__F3 Transcriptomic-Wide Discovery of Direct and Indirect HuR RNA Targets in Activated CD4+ T Cells ENSG00000213658 ENSG00000173039 PMC7417311__F6 Current Sarcoidosis Models and the Importance of Focusing on the Granuloma ENSG00000177606 PMC4498740__F2 Transcriptomic-Wide Discovery of Direct and Indirect HuR RNA Targets in Activated CD4+ T Cells ENSG00000105664 ENSG00000213658 PMC6599319__F1 Simplified schematic illustration of pathways for Wnt/Beta-catenin, ERK/MAPK and PI3K/Akt and PGE2-metabolism ENSG00000134982 ENSG00000166278 ENSG00000148344 PMC5002928__F3 Overlapping RAS/MAPK and PIK3CA/AKT/mTOR signaling pathways and potential therapeutic targets ENSG00000157764 ENSG00000198793 ENSG00000115904 ENSG00000196712 PMC3744367__F1 mTOR couples cellular nutrient sensing to organismal metabolic homeostasis ENSG00000198793 ENSG00000167965 PMC3360922__F1 Murine mutants in the study of systemic iron metabolism and its disorders: an update on recent advances ENSG00000134086 ENSG00000010704 ENSG00000066926 ENSG00000106327 ENSG00000187045 ENSG00000173757 ENSG00000131507 ENSG00000105697 PMC6484299__F7 Schematic representation showing that B‐arrestin2 (ARRB2) negatively regulated NOD2 signalling pathway through the association with TRAF6 in cerebral ischaemia/reperfusion injury ENSG00000167207 ENSG00000141480 ENSG00000100985 ENSG00000175104 PMC7041253__F2 Lipoprotein metabolism dysregulation in lysosomal acid lipase deficiency a) The liver secretes VLDL, which is lipolyzed in the periphery by LPL and HL to generate LDL ENSG00000130164 ENSG00000119655 ENSG00000141458 PMC6207572__F1 Dual functions of IFITM3 in the innate antiviral immune response ENSG00000115415 ENSG00000142089 PMC1359062__F1 Ciliated cell differentiation into goblet cells requires 2 signals ENSG00000163235 ENSG00000138798 ENSG00000146648 PMC12105221__F3 Several classical mechanisms of EDCs that contribute to the development of endometriosis [79, 80] ENSG00000087245 ENSG00000100985 ENSG00000049768 ENSG00000106546 PMC12105221__F2 Estrogenoids contribute to the development of uterine fibroids through alterations in epigenetic pathways [17, 56] ENSG00000151376 ENSG00000266524 ENSG00000115461 PMC8964223__F3 Bile Acids and the Microbiome: Making Sense of This Dynamic Relationship in Their Role and Management in Crohn's Disease ENSG00000167910 PMC11704687__F6 Signaling pathway model ENSG00000133083 ENSG00000109321 ENSG00000089685 ENSG00000150457 ENSG00000131023 PMC5644625__F1 Activation of the complement system ENSG00000039537 ENSG00000113600 ENSG00000244731 ENSG00000166278 ENSG00000182326 ENSG00000236625 PMC3876738__F2 Therapeutic targets in cancer cell metabolism and autophagy ENSG00000152348 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC12105221__F4 How BPA contributes to the development of endometrial hyperplasia, endometrial cancer and infertility through DNA methylation alterations [12, 100] ENSG00000148346 ENSG00000088305 ENSG00000164107 ENSG00000134046 PMC8358862__F8 Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy ENSG00000162711 ENSG00000136869 ENSG00000265972 ENSG00000164690 ENSG00000128602 ENSG00000079999 PMC8313886__F2 N6-methyladenosine methyltransferases: functions, regulation, and clinical potential ENSG00000100811 ENSG00000154370 ENSG00000145388 ENSG00000116731 ENSG00000198793 ENSG00000168036 ENSG00000146457 ENSG00000076003 ENSG00000072364 ENSG00000147421 ENSG00000136997 ENSG00000040199 ENSG00000112378 ENSG00000113360 PMC2040891__F5 UVB acts at both the switch and the switched pathway to trigger UV-induced apoptosis PMC3652575__F2 Activation pathway of pDCs responding to viral nucleic acids and negative regulation of the pDC function by surface receptors ENSG00000239732 ENSG00000172936 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000010671 PMC6543964__F2 Complement cascade and complement regulatory proteins (CRP) ENSG00000274619 ENSG00000000971 ENSG00000178726 PMC7699880__F2 Leptin–melanocortin pathway ENSG00000198576 ENSG00000112246 ENSG00000166603 PMC7071158__F3 Leptin-induced pathways ENSG00000150907 ENSG00000198793 ENSG00000115138 ENSG00000168610 PMC8470674__F1 Sialyltransferase Inhibitors for the Treatment of Cancer Metastasis: Current Challenges and Future Perspectives ENSG00000159921 ENSG00000170191 ENSG00000111726 ENSG00000095380 PMC8464874__F6 L-Plastin Phosphorylation: Possible Regulation by a TNFR1 Signaling Cascade in Osteoclasts ENSG00000291971 ENSG00000163914 ENSG00000175104 PMC3670280__F3 STAT1 as a central mediator of IFNG and TLR4 signal integration in vascular dysfunction ENSG00000105397 ENSG00000140968 ENSG00000172936 ENSG00000136869 ENSG00000125347 PMC6405305__F4 Network modeling of the epithelial-to-mesenchymal transition (EMT) ENSG00000164690 PMC1940036__F6 Wnt/Axin1/Beta-Catenin Signaling Regulates Asymmetric Nodal Activation, Elaboration, and Concordance of CNS Asymmetries ENSG00000156574 ENSG00000164093 PMC6405305__F1 Towards control of cellular decision-making networks in the epithelial-to-mesenchymal transition ENSG00000170558 ENSG00000136997 ENSG00000156273 PMC3960348__F2 Schematic overview of the mTOR signaling pathway with the target position of drugs ENSG00000198793 PMC3960348__F1 Schematic overview of the mTOR signaling pathway with the most important factors and their action ENSG00000177169 ENSG00000118515 ENSG00000168610 PMC4852160__F1 Adenosine monophosphate-activated protein kinase (AMPK) activators for the prevention, treatment and potential reversal of pathological pain PMC3148828__F4 KEGG pathway: cell cycle ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000132646 ENSG00000123374 ENSG00000277273 ENSG00000117399 PMC9562239__F1 Advances in Biomarkers and Endogenous Regulation of Breast Cancer Stem Cells ENSG00000112576 ENSG00000140937 ENSG00000134982 ENSG00000135913 ENSG00000163914 ENSG00000168036 ENSG00000158470 ENSG00000164690 ENSG00000128602 ENSG00000118257 PMC3046919__F7 Proposed model of the process of A20 PMC7565722__F6 TRAIL of oncogenes to apoptosis ENSG00000047936 ENSG00000125995 PMC10459989__F5 Schematic diagram of the plant hormone signal transduction pathway and its correlation with DEGs in response to B ENSG00000105722 ENSG00000291931 ENSG00000083845 PMC6798329__F6 Activation of AhR pathway by mycotoxins (Myctx) ENSG00000110711 ENSG00000140465 ENSG00000106546 PMC4914023__F1 Melanosome biogenesis is a typical model for studying LRO biogenesis ENSG00000118508 ENSG00000123892 ENSG00000107165 ENSG00000123595 ENSG00000292366 PMC7961911__F5 Network/pathway analyses: KDM1A is directly linked to the androgen receptor signaling pathway (green) and is indirectly linked to the immune response, DNA damage response, and cancer cell cycle pathway, among others ENSG00000092853 ENSG00000072274 ENSG00000196591 ENSG00000073111 ENSG00000164104 ENSG00000162961 ENSG00000093009 ENSG00000183765 ENSG00000149311 ENSG00000175054 ENSG00000132646 ENSG00000004487 ENSG00000197299 ENSG00000132341 PMC10526140__F4 Understanding the Clinical Use of Levosimendan and Perspectives on its Future in Oncology ENSG00000012048 ENSG00000175054 ENSG00000136997 ENSG00000145020 ENSG00000139618 PMC10296711__F8 Schematic illustration of the TLR/IL1/IRAK/NFKB inflammatory signaling pathway axis ENSG00000115008 ENSG00000173039 ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000090376 ENSG00000184216 PMC10296711__F5 Schematic illustration of the activation process of TLR receptors and their downstream signaling molecules upon activation forming the TLR-MYD88-IRAK1/4-TRAF6-NFKB/IRF or TLR3/TLR4-TRIF-IRF/NFKB signaling pathways ENSG00000174123 ENSG00000174125 ENSG00000108691 ENSG00000226275 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC6482253__F1 Eukaryotic cell metabolism ENSG00000116688 ENSG00000171109 PMC549180__F2 ErbB signaling pathway ENSG00000169291 ENSG00000002330 ENSG00000198793 PMC4480226__F1 Immune Responses to HCV and Other Hepatitis Viruses ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000164342 PMC10531306__F2 Exon 3-Deleted Growth Hormone Receptor (d3GHR) Polymorphism—A Favorable Backdoor Mechanism for the GHR Function ENSG00000112964 ENSG00000291971 PMC11881607__F3 Deubiquitinases functioning in asthma pathology ENSG00000162711 ENSG00000185515 ENSG00000196591 ENSG00000107485 ENSG00000131323 ENSG00000083799 ENSG00000155313 ENSG00000143258 PMC11881607__F2 E3 ubiquitin ligases inhibit asthma pathology ENSG00000132109 ENSG00000162711 ENSG00000158290 ENSG00000137033 ENSG00000078747 ENSG00000099364 ENSG00000125538 ENSG00000107485 ENSG00000166266 PMC3149764__F3 Emerging roles of JAK–STAT signaling pathways in adipocytes ENSG00000111537 ENSG00000099985 ENSG00000128342 PMC11881607__F1 E3 ubiquitin ligases promote asthma pathology ENSG00000101871 ENSG00000159461 ENSG00000166090 PMC6704453__F8 The Mb maturation process ENSG00000266967 ENSG00000105401 ENSG00000198125 PMC3380732__F7 Analysis of the cell cycle pathway ENSG00000147862 ENSG00000135446 ENSG00000135363 ENSG00000106331 ENSG00000198911 PMC9578007__F1 Regulatory network and interplay of hepatokines, stellakines, myokines and adipokines in nonalcoholic fatty liver diseases and nonalcoholic steatohepatitis ENSG00000105550 ENSG00000288174 ENSG00000169710 ENSG00000132170 ENSG00000109819 ENSG00000150782 ENSG00000108691 ENSG00000189403 ENSG00000136869 ENSG00000100219 ENSG00000112115 ENSG00000079435 ENSG00000096717 ENSG00000146648 ENSG00000106178 PMC8721856__F2 Research progress on SLC7A11 in the regulation of cystine/cysteine metabolism in tumors ENSG00000168003 ENSG00000141867 ENSG00000163930 ENSG00000128272 ENSG00000151012 ENSG00000144895 ENSG00000162772 ENSG00000079999 PMC9086235__F1 Interaction Between Autophagy and JAK/STAT3 Signaling Pathway in Tumors ENSG00000111537 ENSG00000105397 ENSG00000105639 PMC7707178__F2 Sterol regulatory element-binding protein Sre1 regulates carotenogenesis in the red yeast Xanthophyllomyces dendrorhous ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC2831042__F7 Proposed model of neurite outgrowth pathway in postnatal SVZ/RMS-derived neurons ENSG00000070831 PMC11635660__F2 Transcriptomic analysis of dietary G ENSG00000131473 ENSG00000129596 ENSG00000186480 PMC4837953__F2 Characteristics of the interplay among RIPPLY2, TBX6, and MESP2 and their relation in the notch signaling pathway and L/R axis determination ENSG00000156574 ENSG00000203877 ENSG00000188095 ENSG00000149922 PMC3638770__F4 Two major pathways to apoptosis ENSG00000149311 ENSG00000002330 ENSG00000168040 PMC6311798__F1 Red arrowhead represents inhibition ENSG00000171105 ENSG00000005882 PMC11765430__F7 Schematic diagram illustrating the molecular mechanism by which lactate promotes granulosa cell autophagy via the HIF-1A/BNIP3/Beclin-1 signaling pathway ENSG00000171791 PMC4423646__F1 Ischemia/ reperfusion-induced and sepsis-induced endothelial dysfunction is initiated by increased amounts of reactive oxygen species ENSG00000115415 ENSG00000125347 PMC4515436__F4 Short range signalling between the germline stem cells and their niche, which consists of the hub cells and the cyst stem cells ENSG00000133937 ENSG00000128602 ENSG00000146648 PMC9700707__F6 In silico and in vitro analysis of microRNAs with therapeutic potential in atherosclerosis ENSG00000135218 ENSG00000119655 ENSG00000100979 PMC8471358__F3A Ketogenic Diets in Pancreatic Cancer and Associated Cachexia: Cellular Mechanisms and Clinical Perspectives ENSG00000198793 ENSG00000140443 PMC6442489__F7 Schematic illustration of SAA attenuating kidney oxidative stress in 5/6Nx rats ENSG00000086991 ENSG00000079999 PMC2682636__F4 The comorbidity of HIV-associated neurocognitive disorders and Alzheimer’s disease: a foreseeable medical challenge in post-HAART era ENSG00000135218 ENSG00000119912 PMC8637759__F9 Pharmacological Inhibition of HMGB1 Prevents Muscle Wasting ENSG00000189403 PMC4443741__F4 CD44 interferes with apoptosis resistance in HSC/LIC ENSG00000019991 ENSG00000170961 ENSG00000002330 ENSG00000137673 ENSG00000105401 ENSG00000113070 ENSG00000026508 ENSG00000178568 PMC9344092__F2 Phagocytic microglia and macrophages in brain injury and repair ENSG00000135218 ENSG00000137033 ENSG00000118520 PMC5450035__F1 Neuroimmune interface and the role of glia in the pain response ENSG00000108691 ENSG00000111537 ENSG00000198793 ENSG00000189403 ENSG00000121807 ENSG00000115594 PMC6442705__F7 Mechanistic illustration of the effect of alcohol on the dysregulation of genes involving several metabolic pathways leading to alterations in serum metabolomic profiles ENSG00000151224 ENSG00000105550 ENSG00000167910 ENSG00000180432 ENSG00000115271 ENSG00000116761 ENSG00000135929 ENSG00000116984 PMC9497316__F8 Proteomic Analysis of Retinal Mitochondria-Associated ER Membranes Identified Novel Proteins of Retinal Degeneration in Long-Term Diabetes ENSG00000132906 ENSG00000153208 ENSG00000100053 ENSG00000128052 ENSG00000109572 ENSG00000163499 PMC8427189__F2 Recent Progress in the Understanding of the Effect of Sympathetic Nerves on Hair Follicle Growth ENSG00000115138 PMC6907743__F1 Autophagy during viral infection — a double-edged sword ENSG00000177169 ENSG00000213928 ENSG00000119401 ENSG00000169047 ENSG00000163904 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000144895 ENSG00000115415 ENSG00000172936 ENSG00000145782 ENSG00000164342 PMC9588458__F7 Working model of hyperglycemia in DCM ENSG00000128272 ENSG00000171791 PMC5488809__F2 Cancer metabolism as a central driving force of glioma pathogenesis ENSG00000164362 ENSG00000121879 PMC6907743__F3 Autophagy during viral infection — a double-edged sword ENSG00000177169 ENSG00000198382 ENSG00000134109 ENSG00000169047 ENSG00000237693 ENSG00000099940 ENSG00000136874 ENSG00000057663 ENSG00000183735 ENSG00000107862 ENSG00000144895 ENSG00000144848 ENSG00000145782 PMC8287779__F2 Exosomes in lung cancer metastasis and clinical applications: an updated review ENSG00000100985 ENSG00000133422 ENSG00000168610 PMC8796122__F2 Hepatocellular carcinoma (HCC): Epidemiology, etiology and molecular classification ENSG00000291971 ENSG00000134982 ENSG00000100345 ENSG00000173039 ENSG00000168036 ENSG00000162924 PMC7436330__F1 Red arrow shows the classical pathway of LPS-mediated activation of TLR4 that further leads to pyroptosis and releases of IL-1B and IL-18 ENSG00000278718 ENSG00000136869 PMC5635916__F6 Model for how cytosine deamination, base excision repair, and Mlh1-Mlh3 cleavage cooperate to cause R-loop–induced CAG repeat fragility and contractions ENSG00000113456 PMC1975829__F1 Viral infections: beneficial role of eosinophils ENSG00000169896 ENSG00000121053 PMC8253640__F2 Autophagy Regulation on Pyroptosis: Mechanism and Medical Implication in Sepsis ENSG00000198793 ENSG00000198125 ENSG00000285069 PMC9387558__F1 Hormone supply to the pituitary gland: A comprehensive investigation of female-related tumors (Review) ENSG00000291972 ENSG00000112964 ENSG00000157005 PMC3520616__F1 Upstream events in BCR signaling ENSG00000186716 ENSG00000197943 ENSG00000010671 PMC3368902__F1 Postprandial Regulation of Hepatic MicroRNAs Predicted to Target the Insulin Pathway in Rainbow Trout ENSG00000169047 ENSG00000198793 PMC6115711__F3 SUMOylation system and TGFB signaling interplay ENSG00000169554 ENSG00000033800 ENSG00000128602 PMC9576590__F5 Senescence-associated secretory phenotype (SASP) ENSG00000149311 ENSG00000198793 PMC5622153__F3 BACE1-dependent NRG1/ErbB4 signaling pathway involving in the pathogenies of schizophrenia ENSG00000138798 ENSG00000178568 PMC6207918__F10 TGFB/ALK1 signaling at the BBB and regulation of the Slco1a4 gene ENSG00000170365 PMC5622153__F2 Neuregulins proteolytic cleavage pattern by BACE1 ENSG00000138798 ENSG00000178568 PMC6333596__F2 Sonic hedgehog signaling pathway ENSG00000164690 ENSG00000128602 PMC3137255__F2 A simplified model for Hh signaling in mammalian cells ENSG00000144857 ENSG00000166813 ENSG00000128602 PMC4728015__F4 Galactose-1 phosphate uridylyltransferase (GalT) gene: a novel positive regulator of the PI3K/Akt signaling pathway in mouse fibroblasts PMC6611727__F3 Caspases in cell death, inflammation and disease ENSG00000278718 ENSG00000132906 ENSG00000162711 ENSG00000124256 ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000164305 ENSG00000157625 ENSG00000168404 ENSG00000064012 ENSG00000285379 PMC2933570__F1 Coordinated upregulation of cytoprotective genes occurs as a result of Nrf2 activation ENSG00000023909 ENSG00000105227 PMC3225028__F2 WT1/EGR1-mediated Control of STIM1 Expression and Function in Cancer Cells ENSG00000167323 PMC9411204__F4 Proposed biosynthetic pathway of triptonide (2) from 14-hydroxy-dehydroabietadiene (5) in S. cerevisiae ENSG00000184357 PMC3205852__F10 Schematic illustrating the potential role of integrin B3 (ITGB3) in ROS-induced migration and invasion of colorectal cancer cells ENSG00000291971 PMC11491057__F3 Epigenetic modulation and tumor immune efficacy ENSG00000224320 ENSG00000136997 ENSG00000073861 PMC11491057__F2 Tumor immune efficacy by the cGAS-STING pathway ENSG00000134982 PMC4489259__F2 Output of a fictitious combination of gene expression and mutations in version of the Calcium signaling pathway modified for illustrating the examples ENSG00000196296 ENSG00000152495 ENSG00000109743 ENSG00000169885 ENSG00000088256 ENSG00000182621 ENSG00000274542 ENSG00000161714 ENSG00000164742 ENSG00000138193 ENSG00000144935 ENSG00000124181 ENSG00000146648 ENSG00000067177 PMC11491057__F4 Illustrates the mechanisms of metabolic regulation in tumor immune evasion ENSG00000135218 ENSG00000136997 PMC9037156__F9 Icariin: A Potential Molecule for Treatment of Knee Osteoarthritis ENSG00000113070 ENSG00000146648 PMC8255141__F4 Age-Dependent Sensitivity to the Neurotoxic Environmental Metabolite, 1,2-Diacetylbenzene ENSG00000137757 ENSG00000161911 ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC10844364__F4 Novel acylations act as significant regulators in HCC metastasis ENSG00000259207 ENSG00000004455 ENSG00000062485 PMC8869096__F1 Relevance of miR-223 as Potential Diagnostic and Prognostic Markers in Cancer ENSG00000162711 ENSG00000150782 ENSG00000198793 ENSG00000155792 ENSG00000167965 PMC9356732__F4 Comparative Genomics of the Waterfowl Innate Immune System ENSG00000169245 ENSG00000100906 ENSG00000111837 ENSG00000121067 ENSG00000213341 ENSG00000127191 ENSG00000145782 ENSG00000168811 PMC9356732__F3 Comparative Genomics of the Waterfowl Innate Immune System ENSG00000142192 ENSG00000213341 ENSG00000143387 PMC6721756__F7 Role of distinct STAT2 and/or IRF9-dependent pathways in the regulation of distinct subset of antiviral and immunoregulatory genes in response to IFNB and TNF ENSG00000105397 ENSG00000115415 PMC8844014__F8 Alpha-Conotoxin TxIB Improved Behavioral Abnormality and Changed Gene Expression in Zebrafish (Danio rerio) Induced by Alcohol Withdrawal ENSG00000124102 ENSG00000041982 ENSG00000130528 ENSG00000156026 ENSG00000186716 PMC10844364__F1 Main functions and metabolic origins of novel acylations ENSG00000100410 ENSG00000138594 ENSG00000123374 ENSG00000167965 PMC10844364__F2 Novel acylations participate in head and neck cancer metastasis ENSG00000171720 ENSG00000042832 ENSG00000146648 ENSG00000177054 PMC10179672__F4 Ligands, receptors, and transcriptional regulators of Hedgehog signaling pathway ENSG00000128602 PMC10179672__F5 Key components involved in the regulation of activation/inactivation of the canonical or Wnt/Beta-catenin pathway ENSG00000134982 ENSG00000168036 PMC4562871__F1 Conceptual barriers to understanding physical barriers PMC6935754__F1 Hypotheses for the accumulation of amyloidB42 and tau pathology linked to cognitive impairment and epileptogenesis in TLE ENSG00000142192 ENSG00000198793 ENSG00000137845 PMC4522091__F1 Simulation of metabolic flux changes in the central metabolism of the redox reaction manipulated strains ENSG00000122966 ENSG00000166816 PMC5974030__F7 Alterations in Morphology and Adult Neurogenesis in the Dentate Gyrus of Patched1 Heterozygous Mice ENSG00000178403 ENSG00000135547 ENSG00000077279 ENSG00000131095 ENSG00000164690 PMC6975221__F5 KEGG pathway of cardiac muscle contraction (a) and PI3K-Akt signaling pathway (b) ENSG00000041982 ENSG00000002330 ENSG00000130528 ENSG00000118729 ENSG00000198793 ENSG00000136997 ENSG00000198626 ENSG00000182326 PMC8187902__F2 Breast Cancer Resistance to Cyclin-Dependent Kinases 4/6 Inhibitors: Intricacy of the Molecular Mechanisms ENSG00000105325 ENSG00000134982 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000277273 ENSG00000112715 ENSG00000139687 ENSG00000134480 PMC8187902__F3 Breast Cancer Resistance to Cyclin-Dependent Kinases 4/6 Inhibitors: Intricacy of the Molecular Mechanisms ENSG00000178573 ENSG00000135446 ENSG00000198793 ENSG00000160182 ENSG00000129514 ENSG00000123374 ENSG00000185591 ENSG00000105810 ENSG00000146648 PMC9491322__F10 Organic acid metabolism in Chinese dwarf cherry [Cerasus humilis (Bge.) Sok.] is controlled by a complex gene regulatory network ENSG00000090402 ENSG00000146701 PMC6039344__F1 IL-33 signaling ENSG00000102962 ENSG00000105329 ENSG00000099364 ENSG00000198793 ENSG00000149968 ENSG00000113520 ENSG00000164400 ENSG00000160179 ENSG00000118520 ENSG00000106178 ENSG00000163515 ENSG00000137033 ENSG00000109320 ENSG00000109321 ENSG00000173039 ENSG00000007908 ENSG00000145777 ENSG00000185187 ENSG00000099203 ENSG00000143631 ENSG00000007171 ENSG00000115602 ENSG00000108691 ENSG00000177606 ENSG00000132646 ENSG00000102970 ENSG00000172936 ENSG00000115009 PMC6945043__F1 Embryonic origin of the E blastomere and simplified diagram of the gene regulatory network for endomesoderm specification in C ENSG00000184634 ENSG00000125686 PMC4531144__F1 Schematic demonstration of PHB-mediated survival or apoptosis responses in multiple cellular compartments of different cell types and molecular mechanism involved ENSG00000215021 PMC7689594__F6 Sub-network of hub genes related to the disease phenotype of chronic ITP ENSG00000160789 ENSG00000108055 ENSG00000177606 ENSG00000165059 PMC4618091__F2 Scheme of biosynthesis of bile acids and of traditional steroidogenesis ENSG00000167910 ENSG00000179142 ENSG00000099377 ENSG00000135929 PMC8507042__F1 Metabolic reprogramming in epithelial ovarian cancer ENSG00000180210 ENSG00000092621 ENSG00000168610 ENSG00000159399 PMC7042886__F2 APP and ΑB Metabolism ENSG00000142192 ENSG00000119912 PMC8910500__F1 Signal Transduction during Metabolic and Inflammatory Reprogramming in Pulmonary Vascular Remodeling ENSG00000067992 ENSG00000146648 PMC8955121__F6 Rotavirus-Mediated Suppression of miRNA-192 Family and miRNA-181a Activates Wnt/Beta-Catenin Signaling Pathway: An In Vitro Study ENSG00000281324 ENSG00000168036 ENSG00000118971 PMC6095619__F1 cGAS and STING: At the intersection of DNA and RNA virus-sensing networks ENSG00000183735 ENSG00000164430 PMC7709568__F5 Pathway enrichment analysis of (A) significantly higher expressed genes and (B) significantly lower expressed genes in T47D cells after glucose deprivation ENSG00000228716 ENSG00000198743 ENSG00000163918 ENSG00000077514 ENSG00000146143 ENSG00000112118 ENSG00000073111 ENSG00000162772 ENSG00000076003 ENSG00000183765 ENSG00000093009 ENSG00000101868 ENSG00000144554 ENSG00000101773 ENSG00000014138 ENSG00000092853 ENSG00000131747 ENSG00000187741 ENSG00000023909 ENSG00000139618 ENSG00000094804 ENSG00000132646 ENSG00000100479 ENSG00000135476 ENSG00000145386 ENSG00000166851 ENSG00000112312 ENSG00000168003 ENSG00000175054 ENSG00000178607 ENSG00000178573 ENSG00000284099 ENSG00000189403 ENSG00000123374 ENSG00000051180 ENSG00000177084 ENSG00000112742 ENSG00000188486 ENSG00000136492 ENSG00000151012 ENSG00000176153 ENSG00000145604 ENSG00000065328 ENSG00000134057 ENSG00000101255 ENSG00000167325 ENSG00000167996 ENSG00000171848 ENSG00000178966 ENSG00000149554 ENSG00000133119 ENSG00000080839 ENSG00000175305 PMC9583871__F1 Anti-cancer immune responses to DNA damage response inhibitors: Molecular mechanisms and progress toward clinical translation ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000183735 ENSG00000164430 ENSG00000115415 ENSG00000123374 ENSG00000125347 ENSG00000175104 ENSG00000276561 PMC2736391__F2 Simplified model of the leptin signaling pathway ENSG00000173599 ENSG00000170893 ENSG00000124089 ENSG00000166603 PMC8294160__F4 Oxyresveratrol Modulates Genes Associated with Apoptosis, Cell Cycle Control and DNA Repair in MCF-7 Cells ENSG00000172680 ENSG00000148175 ENSG00000164949 PMC8793120__F1 BMI1 in the Initiation, Progression, and Treatment of Hepatocellular Carcinoma ENSG00000168283 ENSG00000168036 PMC7600646__F1 Role of dietary flavonoids in the regulation of the Nrf2/ARE pathway in normal cells ENSG00000079999 PMC8877312__F3 Induced Expression of BPV E4 Gene in Equine Adult Dermal Fibroblast Cells as a Potential Model of Skin Sarcoid-like Neoplasia ENSG00000118007 ENSG00000108055 ENSG00000179091 ENSG00000205250 ENSG00000073111 ENSG00000277273 ENSG00000117399 ENSG00000276876 ENSG00000093009 ENSG00000145604 ENSG00000094804 ENSG00000101972 ENSG00000135446 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000105810 PMC8948490__F1 Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase Pathway in Osteoblasts ENSG00000070831 ENSG00000163914 ENSG00000196712 PMC5548104__F4 Reelin-LIS1-tubulins pathway ENSG00000183785 ENSG00000166579 ENSG00000131462 ENSG00000077279 ENSG00000167552 ENSG00000220205 ENSG00000075702 PMC3003620__F1 PI3K/Akt signaling pathway ENSG00000198793 PMC3147278__F3 Cross-talk between TLR4 and IL-1 signaling pathways ENSG00000115008 ENSG00000115590 ENSG00000136869 ENSG00000175104 ENSG00000115594 PMC5548104__F3 The PI3K-AKT-mTOR signaling pathway ENSG00000140992 ENSG00000134086 ENSG00000002330 ENSG00000198793 ENSG00000136997 ENSG00000105647 ENSG00000121879 ENSG00000124762 ENSG00000025293 ENSG00000187840 ENSG00000196712 PMC4169452__F2 An Integrated Ontology Resource to Explore and Study Host-Virus Relationships ENSG00000088888 ENSG00000121060 PMC7658045__F7 Distinct cation gradients power cholesterol transport at different key points in the Hedgehog signaling pathway ENSG00000154309 ENSG00000164690 ENSG00000128602 PMC8931408__F2 Innate Immune Evasion by Human Respiratory Syncytial Virus ENSG00000162711 ENSG00000213928 ENSG00000167207 ENSG00000187608 ENSG00000142166 ENSG00000183735 ENSG00000088888 ENSG00000115415 ENSG00000135114 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000121060 ENSG00000164342 PMC3844930__F1 Defining mitochondrial dynamics ENSG00000094631 ENSG00000168958 ENSG00000116688 ENSG00000171109 ENSG00000106459 ENSG00000214253 PMC9494868__F7 TOP2A deficit-induced abnormal decidualization leads to recurrent implantation failure via the NFKB signaling pathway ENSG00000131747 ENSG00000146678 PMC11842293__F7 Mechanisms by which OPC mitigates LPS-induced renal tubular injury PMC7865281__F4 Notch-dependent signaling events and signaling crosstalk during the differentiation of MSCs towards osteocytes ENSG00000178860 PMC3844930__F5 Mitophagy pathways ENSG00000116688 ENSG00000158828 PMC8131909__F1 Molecular-targeted therapy toward precision medicine for gastrointestinal caner: Current progress and challenges ENSG00000134982 ENSG00000135446 ENSG00000198793 ENSG00000168036 ENSG00000105810 ENSG00000128602 ENSG00000146648 ENSG00000010671 PMC8581356__F1 Immune Evasion Mechanism and AXL ENSG00000167601 ENSG00000108691 ENSG00000163599 ENSG00000049768 ENSG00000277943 PMC7060614__F1 Alterations of the propionate pathway in times of acute metabolic decompensation ENSG00000175198 ENSG00000171444 ENSG00000124370 ENSG00000168288 ENSG00000036473 ENSG00000116761 PMC2645295__F1 Airway Smooth Muscle Cell as an Inflammatory Cell ENSG00000105397 ENSG00000102871 ENSG00000127191 PMC2753863__F1 Examination of Association of Genes in the Serotonin System to Autism ENSG00000139287 ENSG00000129167 PMC7780675__F8 Schematic illustrating the role of MGMT in HR signaling in NPC cells ENSG00000012048 ENSG00000170430 ENSG00000051180 ENSG00000139618 PMC8056677__F7 Calvin (left) and C4-Dicarboxylic acid cycle (right) in S ENSG00000197713 PMC11874147__F3 FAO signaling pathway and ferroptosis in BC ENSG00000169554 ENSG00000111537 ENSG00000151012 ENSG00000134824 ENSG00000167468 ENSG00000149485 ENSG00000136997 ENSG00000168610 ENSG00000026103 PMC11874147__F2 Dysregulation of lipid synthesis and related pro-oncogenic signaling pathways involved in BC development ENSG00000131473 ENSG00000113161 ENSG00000146648 ENSG00000026103 PMC4071059__F3 Molecular Signals Elicited by GPCR Agonists in Hypertension, Cardiovascular Remodeling: Are MMPs and ADAMs Elusive Therapeutic Targets? ENSG00000137834 ENSG00000136535 ENSG00000285109 ENSG00000198793 ENSG00000284161 PMC7979820__F2 Epigenetic mechanisms in breast cancer therapy and resistance ENSG00000050165 ENSG00000168036 ENSG00000164690 PMC7979820__F4 Epigenetic mechanisms in breast cancer therapy and resistance ENSG00000117713 ENSG00000117139 ENSG00000129514 ENSG00000055609 PMC2909599__F1 GLP-1 acts by means of the GLP-1-R to stimulate adenylyl cyclase (AC), and thereby cAMP production, and to activate the cAMP-binding proteins PKA and Epac ENSG00000150907 ENSG00000146648 ENSG00000140443 PMC11912584__F1 HRS-4642 can inhibit KRAS G12D binding to SOS or RAF1 and inhibit downstream MEK-ERK signaling pathways KRAS: Kirsten rat sarcoma viral oncogene homologue SOS: Guanine nucleotide exchange factors (GEFs, e ENSG00000183735 ENSG00000002330 ENSG00000070831 ENSG00000156299 ENSG00000138798 ENSG00000198793 PMC8571914__F2 S1P Signaling Pathways in Pathogenesis of Type 2 Diabetes ENSG00000163914 ENSG00000127191 ENSG00000183018 PMC8359440__F5 Enantiomer‐specific pharmacokinetics of D,L‐3‐hydroxybutyrate: Implications for the treatment of multiple acyl‐CoA dehydrogenase deficiency ENSG00000131473 ENSG00000117305 PMC4874878__F6 Altogether, our findings are summarized in ENSG00000150782 ENSG00000167910 ENSG00000125538 ENSG00000169710 PMC6826160__F5 ROS‐dependent priming and activation of the intrinsic cell death pathway ENSG00000132906 PMC4755889__F3 Interconnections between the Hippo and RB/E2F pathways ENSG00000101868 ENSG00000094804 ENSG00000162521 ENSG00000112118 ENSG00000150457 ENSG00000076003 ENSG00000131023 PMC10813042__F3 Antioxidant mechanism of estrodiol ENSG00000291971 ENSG00000146648 PMC4755889__F1 Regulation of transcription by YAP/TAZ transcriptional co-factors and the regulation of YAP/TAZ activity in mammalian cells ENSG00000126016 ENSG00000134982 ENSG00000109321 ENSG00000135903 ENSG00000168036 ENSG00000150457 ENSG00000076003 ENSG00000131023 ENSG00000089225 ENSG00000186575 ENSG00000089685 ENSG00000164690 ENSG00000146648 PMC7400965__F2 Difference between SHARPIN presence and absence in regulating the NFKB signaling pathway ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC6358228__F1 Canonical pathway network analysis ENSG00000291972 ENSG00000105329 ENSG00000125851 ENSG00000170893 ENSG00000175426 ENSG00000112715 PMC7400965__F3 SHARPIN regulates multiple signaling pathways in tumorigenesis ENSG00000135903 ENSG00000100146 PMC4152724__F2 Immunoregulatory molecules are master regulators of inflammation during the immune response ENSG00000291603 ENSG00000111537 ENSG00000115415 ENSG00000134982 ENSG00000116717 ENSG00000168610 PMC4152724__F1 Immunoregulatory molecules are master regulators of inflammation during the immune response ENSG00000111537 ENSG00000134982 PMC6351787__F5 Hexosamine pathway ENSG00000039537 ENSG00000147162 ENSG00000198408 ENSG00000166278 PMC9132697__F2 Mechanisms Involved in Gut Microbiota Regulation of Skeletal Muscle ENSG00000198793 ENSG00000277140 PMC5892012__F1 TERT levels affect EBV latent/lytic status ENSG00000156127 ENSG00000164362 PMC5448608__F5 Schema of BTB and CNC homology 2 (BACH2) interaction in the nuclear factor‐KB (NFKB) signaling pathway ENSG00000157625 ENSG00000175104 PMC5834263__F11 Sensitization of multidrug-resistant cancer cells to Hsp90 inhibitors by NSAIDs-induced apoptotic and autophagic cell death ENSG00000284774 ENSG00000198793 ENSG00000168610 PMC3432834__F2 Two NFKB activation pathways induced by RANK, CD40, and LtB R signaling ENSG00000104856 ENSG00000173039 ENSG00000111321 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC10153643__F2 Thermogenic adipose tissue in lipid metabolism and atherosclerotic cardiovascular disease: lessons from studies in mice and humans ENSG00000130164 ENSG00000169174 PMC7291112__F1 Roles of gga-miRNAs in host response to infectious bursal disease virus (IBDV) infection ENSG00000170677 ENSG00000168310 PMC7917704__F6 HMGA2 is regulated by the RAF kinase inhibitor protein (RKIP) pathway ENSG00000169439 PMC7917704__F5 HMGA2 induces EMT by activation of different signaling transducers ENSG00000170961 ENSG00000074181 ENSG00000198793 ENSG00000168610 PMC3110682__F1 Hypothesized mechanisms of physical activity in colon cancer ENSG00000134982 PMC6216001__F6 Network generation of CDK1, YWHAZ and PRKDC based on significantly differential genes found between cells with PAX2 over-expression and those that lack that over-expression ENSG00000066933 ENSG00000152661 ENSG00000145147 ENSG00000186638 ENSG00000119969 ENSG00000087586 ENSG00000057294 ENSG00000138138 ENSG00000169118 ENSG00000184203 ENSG00000128833 ENSG00000100504 ENSG00000139687 ENSG00000140443 ENSG00000253729 ENSG00000147044 ENSG00000166130 ENSG00000167987 ENSG00000130638 ENSG00000138594 ENSG00000114127 ENSG00000099246 ENSG00000165219 ENSG00000104408 ENSG00000149311 ENSG00000177189 ENSG00000156110 ENSG00000013441 ENSG00000138756 ENSG00000159352 ENSG00000127824 PMC12187357__F1 Microenvironment drivers of the EMT ENSG00000169554 ENSG00000275385 PMC7982393__F1 Physiological and pathological functions of the RAS ENSG00000175054 ENSG00000130234 PMC6277881__F4 Subolesin/Akirin function in immune response pathways PMC7268348__F7 MYC and HIF-1 regulate glucose metabolism ENSG00000136997 PMC12187357__F5 Signaling pathways responsible for EMT-induced drug resistance in HCC ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC12187357__F4 miRNAs cause EMT-induced drug resistance ENSG00000107562 ENSG00000134982 ENSG00000168036 ENSG00000121966 PMC4426090__F6 Proteomic Profiling of a Biomimetic Drug Delivery Platform ENSG00000292348 ENSG00000136541 ENSG00000169896 ENSG00000166086 ENSG00000070831 ENSG00000154721 ENSG00000115232 ENSG00000135605 ENSG00000121966 ENSG00000154096 PMC1557825__F4 Ordering and correlation network diagrams for the significant pathways ENSG00000164904 ENSG00000122420 ENSG00000128918 ENSG00000050628 ENSG00000120915 ENSG00000160013 ENSG00000125384 ENSG00000148344 ENSG00000182621 ENSG00000124212 ENSG00000073756 ENSG00000134716 ENSG00000095596 ENSG00000111012 ENSG00000072210 ENSG00000143149 ENSG00000019186 ENSG00000095303 ENSG00000198074 ENSG00000160951 PMC12187357__F3 NFKB causes EMT-induced drug resistance ENSG00000169554 ENSG00000148400 ENSG00000122691 PMC4492816__F6 Definition of the early fracture healing pathwaySchematic detailing the role of the early inflammatory pathway in fracture healing ENSG00000108691 ENSG00000099985 ENSG00000121807 PMC9102269__F9 Is P-Glycoprotein Functionally Expressed in the Limiting Membrane of Endolysosomes? A Biochemical and Ultrastructural Study in the Rat Liver ENSG00000102189 ENSG00000103769 ENSG00000184207 PMC9695947__F1 Farnesoid X Receptor as a Master Regulator of Hepatotoxicity ENSG00000138075 ENSG00000167910 ENSG00000180432 ENSG00000143921 ENSG00000135929 PMC4638128__F2 Microhomology-mediated end joining: a back-up survival mechanism or dedicated pathway? ENSG00000143799 ENSG00000105486 ENSG00000177084 PMC8290460__F1 MicroRNA-129 in cancer and non-cancerous diseases (Review) ENSG00000198793 PMC4638128__F4 Microhomology-mediated end joining: a back-up survival mechanism or dedicated pathway? ENSG00000051180 ENSG00000177084 PMC3792734__F1 Main biosynthetic pathway of saturated and monounsaturated fatty acids ENSG00000170522 ENSG00000169710 ENSG00000099194 PMC3863344__F2 Downstream targets of p38 MAPK ENSG00000115415 ENSG00000136997 PMC2930200__F1 Molecular machinery of myelin gene transcription in Schwann cells ENSG00000197971 ENSG00000158887 ENSG00000100146 PMC10376943__F4 FGF1 Protects MCF-7 Cells against Taltobulin through Both the MEKs/ERKs and PI3K/AKT Signaling Pathway ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC3579281__F1 Simplified overview of inflammation-orchestrated signal transduction that induces pro-tumourigenic responses in glioblastoma ENSG00000163464 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC8107475__F1 Abscisic Acid as an Emerging Modulator of the Responses of Plants to Low Oxygen Conditions ENSG00000105722 ENSG00000107669 ENSG00000163788 PMC6873535__F2 Effect of RAS signaling components on neural stem cell differentiation ENSG00000157764 ENSG00000196712 ENSG00000179295 PMC6873535__F1 RAS-ERK signaling pathway and associated disorders ENSG00000157764 ENSG00000115904 ENSG00000196712 ENSG00000062485 PMC2904042__F2 Concurrent deregulation of the top five canonical pathways in retinoblastoma (RB) tumors ENSG00000149311 ENSG00000012048 ENSG00000144554 PMC4626012__F1 Role of epidermal growth factor receptor in acute and chronic kidney injury ENSG00000291971 ENSG00000113070 ENSG00000198793 ENSG00000146648 PMC7218232__F5 Metabolite and miRNA changes associated with 3R4F CS-induced immune response ENSG00000081181 ENSG00000100412 ENSG00000197629 ENSG00000118520 ENSG00000036473 ENSG00000116649 ENSG00000102172 ENSG00000007171 PMC8864926__F1 Metabolic engineering of Escherichia coli for efficient biosynthesis of butyl acetate ENSG00000123268 PMC3109859__F6 Finding Homes for Orphan Cytochrome P450s: CYP4V2 and CYP4F22 in Disease States ENSG00000179148 ENSG00000179477 ENSG00000171954 PMC6139646__F6 Metabolic pathways impacted by PEPCK in the small intestine of mice ENSG00000122966 ENSG00000172005 PMC8126328__F1 G-Protein-coupled Estrogen Receptor 1 Agonist G-1 Perturbs Sunitinib Resistance-related Phosphoproteomic Signatures in Renal Cell Carcinoma ENSG00000291971 ENSG00000198793 ENSG00000164327 ENSG00000141564 ENSG00000089159 ENSG00000160007 ENSG00000163558 ENSG00000149269 ENSG00000106070 ENSG00000129245 ENSG00000130402 ENSG00000119396 ENSG00000177600 ENSG00000136068 ENSG00000142627 ENSG00000100345 ENSG00000132356 ENSG00000160741 ENSG00000063245 ENSG00000204120 ENSG00000177606 ENSG00000112640 ENSG00000204673 ENSG00000184371 ENSG00000137076 ENSG00000146648 ENSG00000130669 ENSG00000101608 PMC11506648__F6 AREG’s role in ESCC-MSC interactions ENSG00000178860 ENSG00000109321 ENSG00000078098 ENSG00000146648 PMC8869630__F1 Small Hero with Great Powers: Vaccinia Virus E3 Protein and Evasion of the Type I IFN Response ENSG00000124256 ENSG00000213928 ENSG00000276561 ENSG00000142166 ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000131323 ENSG00000168404 ENSG00000135828 ENSG00000175104 ENSG00000285379 PMC4427618__F2 Coordination of developmental signalling pathways by USP9X ENSG00000078747 ENSG00000198742 ENSG00000138798 ENSG00000198793 ENSG00000164327 ENSG00000101752 PMC8082835__F7 Glutaminolysis dynamics during astrocytoma progression correlates with tumor aggressiveness ENSG00000125166 ENSG00000135423 ENSG00000166123 PMC8678479__F2 Pyroptosis: A New Insight Into Eye Disease Therapy ENSG00000162711 ENSG00000172936 ENSG00000157625 ENSG00000174611 PMC11033252__F6 Mechanisms of human NLRP6 inflammasome activation ENSG00000278718 ENSG00000162711 ENSG00000226275 ENSG00000174885 ENSG00000136869 PMC11033252__F5 Mechanisms of human NLRP3 inflammasome activation and regulation ENSG00000278718 ENSG00000162711 ENSG00000088888 ENSG00000172936 ENSG00000064012 ENSG00000267534 ENSG00000115594 PMC9117271__F1 Apoptotic signaling in VC ENSG00000067900 ENSG00000168040 ENSG00000115317 ENSG00000026103 PMC6906145__F1 Regulatory pathways for Arid5a under TLR4 signaling ENSG00000196843 ENSG00000136869 ENSG00000168610 ENSG00000123124 PMC10253673__F1 Potential mechanisms by which alcohol modulates Alzheimer’s disease (AD) pathology ENSG00000142192 ENSG00000198793 PMC7219141__F6 Hypothetical signalling pathway showing that dysfunctional TGFB network signalling regulates tissue fibrosis and may play a role in this PCOS-specific insulin resistance and its limited response to exercise training ENSG00000169047 ENSG00000198793 PMC3840259__F9 A summary schematic overview highlights the signaling pathway proposed in the present study PMC5501176__F4 Roles of Autophagy signaling pathway in cancer in type 2 diabetes ENSG00000140992 ENSG00000164327 PMC8995973__F2 Pyroptosis by ncRNA: A Novel Research Direction ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000091592 ENSG00000145649 ENSG00000147697 ENSG00000073605 PMC8526866__F7 SUZ12 Loss Amplifies the Ras/ERK Pathway by Activating Adenylate Cyclase 1 in NF1-Associated Neurofibromas ENSG00000164742 ENSG00000108799 ENSG00000162521 ENSG00000074266 ENSG00000178691 PMC5501176__F3 Roles of SIRT1 signaling pathway in cancer in type 2 diabetes ENSG00000109819 ENSG00000149311 ENSG00000109320 ENSG00000198793 ENSG00000112715 ENSG00000096717 PMC5501176__F2 Roles of mTOR signaling pathway in cancer in type 2 diabetes ENSG00000140992 ENSG00000104365 ENSG00000169710 ENSG00000112715 ENSG00000096717 ENSG00000187840 PMC7374064__F6 Mechanical stretch regulates the expression of specific miRNA in extracellular vesicles released from lung epithelial cells ENSG00000147649 ENSG00000142192 ENSG00000112242 ENSG00000181163 ENSG00000136997 ENSG00000185129 ENSG00000168610 ENSG00000139687 ENSG00000123908 PMC8403526__F2 SOCS, SPRED, and NR4a: Negative regulators of cytokine signaling and transcription in immune tolerance ENSG00000111537 PMC10536258__F3 Brain pericyte biology: from physiopathological mechanisms to potential therapeutic applications in ischemic stroke ENSG00000163739 ENSG00000112715 ENSG00000142224 PMC7264673__F1 Does High Cardiorespiratory Fitness Confer Some Protection Against Proinflammatory Responses After Infection by SARS‐CoV‐2? ENSG00000125538 ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000184216 PMC10536258__F2 Brain pericyte biology: from physiopathological mechanisms to potential therapeutic applications in ischemic stroke ENSG00000198793 ENSG00000173786 ENSG00000183840 PMC5868458__F3 Protein expression levels of healthy cerebral cortex cells mapped onto the GBM pathway map from the TCGA data set ENSG00000148798 ENSG00000145321 PMC6275123__F1 Wnt/Beta-catenin pathway ENSG00000281324 ENSG00000134982 PMC6275123__F3 The IGF2 signaling pathway ENSG00000002330 ENSG00000005882 ENSG00000198793 ENSG00000140443 PMC9289111__F6 Bifidobacterium infantis Promotes Foxp3 Expression in Colon Cells via PD-L1-Mediated Inhibition of the PI3K-Akt-mTOR Signaling Pathway ENSG00000198793 ENSG00000049768 PMC4483763__F5 Key signals mediating progenitor fate decisions during hepatogenesis ENSG00000019991 ENSG00000099985 ENSG00000156574 PMC4037363__F3 Trafficking of endosomal Toll-like receptors ENSG00000172936 ENSG00000276561 PMC4901281__F7 In-depth comparative transcriptome analysis of intestines of red swamp crayfish, Procambarus clarkii, infected with WSSV ENSG00000110395 ENSG00000136997 ENSG00000137193 PMC8427320__F3 Potentials of carbon monoxide-releasing molecules in cancer treatment: An outlook from ROS biology and medicine ENSG00000291971 ENSG00000170558 ENSG00000198793 PMC8269350__F1 Possible Link between SARS-CoV-2 Infection and Parkinson’s Disease: The Role of Toll-Like Receptor 4 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC3082271__F5 NVN for Putative CHS-Mediated (CHS4) Medicarpin Biosynthesis.Nodes in the network resemble individual genes, and the connecting edges represent coexpressed links ENSG00000116984 PMC8781535__F2 Deciphering Respiratory-Virus-Associated Interferon Signaling in COPD Airway Epithelium ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000185436 ENSG00000142166 PMC7804410__F4 The selected miRNAs target genes in KF-Tx cells ENSG00000177455 ENSG00000132906 ENSG00000124102 ENSG00000103479 ENSG00000171105 ENSG00000002330 ENSG00000186716 ENSG00000173039 PMC5840987__F1 Canonical and non-canonical Wnt signaling pathways.(Left) Unstimulated Wnt pathway results in constitutive Beta-catenin degradation ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000177606 ENSG00000168036 PMC12042445__F8 Antioxidant and mitochondrial protective effects of EPS in PD ENSG00000079999 PMC3273421__F2 Myostatin and activin signaling in muscle PMC4817802__F4 Role of histone PTMs in DNA damage repair ENSG00000188486 ENSG00000137075 ENSG00000155827 ENSG00000101236 ENSG00000285152 ENSG00000112130 ENSG00000163481 ENSG00000149311 ENSG00000012048 ENSG00000163961 ENSG00000121481 ENSG00000105982 ENSG00000170633 ENSG00000173456 PMC1900132__F1 HCMV MIE promoter/enhancer and its cis-acting elements ENSG00000105722 ENSG00000100811 ENSG00000185591 PMC3947622__F1 Molecular programming of B cell memory ENSG00000186716 ENSG00000145321 PMC8117345__F5 DNA Repair Repertoire of the Enigmatic Hydra ENSG00000012061 ENSG00000134574 ENSG00000167986 ENSG00000136936 PMC8797306__F2 Screening and verifying key genes with poor prognosis in colon cancer through bioinformatics analysis ENSG00000145604 ENSG00000108055 ENSG00000134982 ENSG00000115942 ENSG00000123374 ENSG00000205250 ENSG00000277273 PMC7448422__F7 Schematic diagram of the potential mechanism underlying the miR-590/LRP6/EMT axis in ESCC ENSG00000281324 ENSG00000170558 PMC7518857__F4 Hedgehog signalling is initiated at primary cilia ENSG00000143147 ENSG00000128602 ENSG00000281857 PMC7518857__F6 INPP5E regulates Hedgehog signalling via ciliary phosphoinositide metabolism ENSG00000143147 ENSG00000148384 ENSG00000128602 PMC9229940__F3 Toxic Effects and Tumor Promotion Activity of Marine Phytoplankton Toxins: A Review ENSG00000205221 PMC7987878__F1 NRs promote tolerance increasing recognition and degradation of apoptotic cells ENSG00000153208 ENSG00000135218 ENSG00000057663 PMC9548020__F5 Treatment effects of the EGFR pathway drugs on head and neck cancer stem cells ENSG00000138798 ENSG00000026508 ENSG00000146648 PMC5931986__F3 Nucleolar response to nuclear or nucleolar DNA damage ENSG00000149311 ENSG00000175054 ENSG00000101751 ENSG00000181163 ENSG00000134982 ENSG00000081377 ENSG00000166851 ENSG00000166169 PMC3941198__F1 Milk lipid secretion: recent biomolecular aspects ENSG00000158669 ENSG00000285482 ENSG00000198670 PMC9259951__F2 Trends in the Contribution of Genetic Susceptibility Loci to Hyperuricemia and Gout and Associated Novel Mechanisms ENSG00000159167 ENSG00000162711 ENSG00000281178 ENSG00000009950 ENSG00000102908 ENSG00000100344 ENSG00000084734 ENSG00000136869 ENSG00000118777 ENSG00000140443 ENSG00000109667 PMC4361071__F1 Notch signaling pathway.(a) Schematic depiction of mammalian Notch receptors and DSL ligands ENSG00000140564 ENSG00000148400 ENSG00000074181 ENSG00000138798 PMC3514827__F1 Using components of the Vitamin D pathway to prevent/treat colon cancer ENSG00000134982 ENSG00000168036 ENSG00000196628 ENSG00000125968 PMC7692253__F2 Identified B lymphocyte‐induced maturation protein‐1 (Blimp‐1) targets in mononuclear phagocytes (MNPs) ENSG00000169245 ENSG00000108691 ENSG00000204103 ENSG00000088827 ENSG00000140968 ENSG00000163131 ENSG00000108700 ENSG00000137265 ENSG00000142405 PMC8129319__F5 WW45 inhibits breast cancer cell proliferation by the Hedgehog signaling pathway ENSG00000164161 ENSG00000164690 ENSG00000128602 PMC4322894__F1 CXCL12 is highly expressed in tissues like lungs, liver, and bone marrow and is also secreted by tumor and stromal cells ENSG00000107562 ENSG00000002330 ENSG00000070831 ENSG00000163914 ENSG00000168036 ENSG00000138777 ENSG00000121966 PMC16561__F6 The signaling pathway from the upstream protein-tyrosine kinases, Lyn/Syk/Btk, to cytokine gene expression through intermediate signaling proteins, PKCBI/JNK ENSG00000010671 PMC9632461__F6 CA regulates the mitochondrial quality and enhances the vitality of LMSCs ENSG00000116688 ENSG00000158828 ENSG00000171109 ENSG00000214253 PMC3605164__F2 New insight into the mechanisms underlying the function of the incretin hormone glucagon-like peptide-1 in pancreatic Beta-cells ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8924518__F3 Therapeutic Effects of Berberine on Liver Fibrosis are associated With Lipid Metabolism and Intestinal Flora ENSG00000105550 PMC2997801__F1 Positioning NFKB in multiple myeloma ENSG00000124102 ENSG00000111321 ENSG00000131323 ENSG00000083799 ENSG00000127191 ENSG00000168610 ENSG00000140443 PMC12028784__F7 This study ENSG00000136869 ENSG00000162692 PMC4905465__F6 Distinct lymphocyte antigens 6 (Ly6) family members Ly6D, Ly6E, Ly6K and Ly6H drive tumorigenesis and clinical outcome ENSG00000139193 ENSG00000198851 ENSG00000278032 ENSG00000135903 ENSG00000112715 ENSG00000131126 ENSG00000106546 ENSG00000163631 ENSG00000095585 ENSG00000167656 ENSG00000111537 ENSG00000274488 ENSG00000172216 ENSG00000177606 ENSG00000160886 PMC8158527__F1 Clinical Application of Porous Tantalum and Its New Development for Bone Tissue Engineering ENSG00000170365 ENSG00000291837 ENSG00000168036 PMC9157711__F2 Hepatitis B virus in development of hepatocellular carcinoma: Focus on covalently closed circular DNA ENSG00000244509 ENSG00000128917 ENSG00000148400 ENSG00000132646 ENSG00000179750 ENSG00000129514 ENSG00000174579 ENSG00000168610 PMC3103888__F1 TIRs signaling pathway ENSG00000174123 ENSG00000174125 ENSG00000183735 ENSG00000187554 ENSG00000172936 ENSG00000184216 ENSG00000164342 PMC2432088__F1 WNT SIGNALING PATHWAY: AGING GRACEFULLY AS A PROTECTIONIST? ENSG00000163914 ENSG00000168036 PMC8180168__F1 Stem cells and exosomes: promising candidates for necrotizing enterocolitis therapy ENSG00000160180 ENSG00000168036 ENSG00000293532 PMC6284771__F8 Schematic model illustrating that miR-10b mediated function in osteogenic and adipogenic differentiation of hADSCs PMC7161552__F10 Modeling Neoadjuvant chemotherapy resistance in vitro increased NRP‐1 and HER2 expression and converted MCF7 breast cancer subtype ENSG00000134057 ENSG00000146648 PMC6175900__F2 Evolutionarily selected pathway (ESP) map ENSG00000105613 ENSG00000174799 ENSG00000169047 ENSG00000173905 ENSG00000101868 ENSG00000117154 ENSG00000103449 ENSG00000018236 ENSG00000130340 ENSG00000143546 ENSG00000135636 ENSG00000135473 ENSG00000103510 ENSG00000092847 ENSG00000151615 ENSG00000197694 ENSG00000105397 ENSG00000144589 ENSG00000146054 ENSG00000204120 ENSG00000144857 ENSG00000070371 ENSG00000132964 ENSG00000136448 ENSG00000127616 ENSG00000110237 ENSG00000163064 ENSG00000105647 ENSG00000049618 ENSG00000112659 ENSG00000169032 ENSG00000121879 ENSG00000292366 ENSG00000160796 ENSG00000166501 ENSG00000197386 ENSG00000136518 ENSG00000272333 ENSG00000124181 ENSG00000155657 ENSG00000198947 ENSG00000118058 ENSG00000074590 ENSG00000164379 ENSG00000157764 ENSG00000116044 ENSG00000138411 ENSG00000138759 ENSG00000086758 ENSG00000131023 ENSG00000149311 ENSG00000127481 ENSG00000156925 ENSG00000134853 ENSG00000134460 ENSG00000142798 ENSG00000164091 ENSG00000115970 ENSG00000155974 ENSG00000101407 ENSG00000137203 ENSG00000106070 ENSG00000125686 ENSG00000189132 ENSG00000198028 ENSG00000106346 ENSG00000292332 ENSG00000196712 ENSG00000130939 ENSG00000134376 ENSG00000148400 ENSG00000139618 ENSG00000110841 ENSG00000109805 ENSG00000026508 ENSG00000080603 ENSG00000130254 ENSG00000178568 ENSG00000137474 ENSG00000104517 ENSG00000023287 ENSG00000168036 ENSG00000104833 ENSG00000099381 ENSG00000101680 ENSG00000163631 ENSG00000175054 ENSG00000186575 ENSG00000107862 ENSG00000100412 ENSG00000177084 ENSG00000112742 ENSG00000253729 ENSG00000196367 ENSG00000005339 ENSG00000081237 ENSG00000064393 ENSG00000153201 ENSG00000131508 ENSG00000120899 ENSG00000054118 ENSG00000175305 ENSG00000149480 PMC6036173__F2 Screening Mammalian Cochlear Hair Cells to Identify Critical Processes in Aminoglycoside-Mediated Damage ENSG00000105664 ENSG00000070831 ENSG00000291971 ENSG00000135446 ENSG00000198793 ENSG00000136869 ENSG00000146648 PMC5114520__F1 Double-strand break can be repaired by cNHEJ with minimal end processing ENSG00000143799 ENSG00000012048 ENSG00000105486 ENSG00000051180 ENSG00000139618 PMC3095949__F3 Functional pathway analysis of the 28-gene prognostic signature using Ingenuity Pathway Analysis ENSG00000169908 ENSG00000262406 ENSG00000117228 ENSG00000142798 ENSG00000213341 ENSG00000100290 ENSG00000109084 ENSG00000138166 ENSG00000188021 ENSG00000165458 ENSG00000165392 ENSG00000171848 ENSG00000163993 ENSG00000185591 ENSG00000213809 ENSG00000101138 ENSG00000095002 ENSG00000122512 PMC7084279__F7 Detailed analysis of the 13 out of the 23 screened genes in “monoamine GPCRs” pathway ENSG00000180720 ENSG00000158748 ENSG00000135914 ENSG00000043591 ENSG00000102468 ENSG00000149295 ENSG00000168830 ENSG00000276825 ENSG00000133019 ENSG00000184845 ENSG00000169676 ENSG00000179097 ENSG00000148680 ENSG00000113749 ENSG00000196639 ENSG00000179546 PMC7397304__F6 Possible antioxidant signaling pathways regulating dexamethasone-induced muscle apoptosis by quercetin ENSG00000002330 ENSG00000150907 PMC6073502__F3 Interaction of proteins 3 days after hyperoxia ENSG00000074800 ENSG00000184900 ENSG00000163631 PMC8548344__F2 Crosstalk between Hedgehog and other pathways in the intestinal tract ENSG00000167207 ENSG00000168036 ENSG00000134245 ENSG00000133961 ENSG00000128602 PMC8548344__F1 Paracrine Hh signalling in the mammalian intestine ENSG00000180447 ENSG00000164161 ENSG00000128602 PMC6073502__F2 Proteins with influence on cell-death related signal transduction (green/light green: up-regulation, red/light red: down-regulation) ENSG00000168028 ENSG00000172867 ENSG00000074800 ENSG00000221914 ENSG00000112818 ENSG00000165283 ENSG00000163631 ENSG00000119125 PMC6073502__F1 Ingenuity pathways analysis (IPA) functional network generated for data of NH0-, NH3-, and NH7-groups ENSG00000172867 ENSG00000162889 ENSG00000171105 ENSG00000065559 ENSG00000112818 ENSG00000165283 ENSG00000125538 ENSG00000100078 ENSG00000146678 ENSG00000184900 ENSG00000198911 ENSG00000119125 ENSG00000062485 PMC9310475__F1 Which patients are prone to suffer liver metastasis? A review of risk factors of metachronous liver metastasis of colorectal cancer ENSG00000157764 ENSG00000134982 ENSG00000198793 ENSG00000145321 ENSG00000168036 ENSG00000146648 PMC11607765__F1 Clinical role of Aldehyde dehydrogenase-1A1 (ALDH1A1) in pancreatic cancer ENSG00000291971 PMC4899241__F6 Biological function of extracellular HMGB1 is redox dependent ENSG00000107562 ENSG00000189403 ENSG00000150455 PMC8981326__F5 Glycosphingolipid-Glycan Signatures of Acute Myeloid Leukemia Cell Lines Reflect Hematopoietic Differentiation ENSG00000102145 ENSG00000121578 ENSG00000159216 ENSG00000064225 ENSG00000198408 ENSG00000180549 PMC3187860__F1 Brain Arteriovenous Malformation Pathogenesis: A Response-to-Injury Paradigm ENSG00000196411 PMC5450331__F1 Signaling pathways of TLRs include MYD-88 independent and MYD-88 dependent pathways ENSG00000239732 ENSG00000187554 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000168040 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC7251742__F9 Hypothetical scheme furtherly illustrates the mechanism of which polydatin improves osteogenic differentiation of hBMSCs via stimulating the expression of TAZ in the BMP2-Wnt/Beta-catenin pathway ENSG00000134982 ENSG00000168036 PMC5954114__F2 GAS6/TAM signaling pathway PMC5954114__F1 GAS6 and representative TAM family receptor ENSG00000138798 PMC8397419__F8 Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Improve Ovarian Function and Proliferation of Premature Ovarian Insufficiency by Regulating the Hippo Signaling Pathway ENSG00000178860 ENSG00000150457 ENSG00000131023 PMC10138370__F6 GCN2/eIF2A/ATF4 Pathway in the Liver and Induction of FGF21 in Young Goats Fed a Protein- and/or Phosphorus-Reduced Diet ENSG00000284320 ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC4878851__F5 Lifecycle of cardiac Nav1.5 and potential phenotypic modifiers ENSG00000182533 ENSG00000069869 ENSG00000150907 ENSG00000089225 PMC4615692__F1 Bile acid metabolism and signaling in cholestasis, inflammation and cancer ENSG00000180432 ENSG00000099377 ENSG00000135929 PMC4125208__F4 Ingenuity pathway analysis (IPA) revealed TGF-beta signaling as the top “connected” network of differentially methylated candidates in HDM-exposed group ENSG00000157933 ENSG00000137504 ENSG00000292099 ENSG00000164326 ENSG00000136696 ENSG00000152785 ENSG00000110057 ENSG00000038945 ENSG00000284017 PMC3368606__F2 Assembly of targeting patches and inside–out orientation of the secretory pathway ENSG00000070831 ENSG00000163914 PMC5752491__F3 Integrated analysis of chromosome copy number variation and gene expression in cervical carcinoma ENSG00000134982 ENSG00000091651 ENSG00000277273 ENSG00000117399 ENSG00000276876 ENSG00000093009 ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000094804 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 PMC3801100__F1 RSK isoforms control motility and other aspects of tumor cell invasion and metastasis ENSG00000163914 ENSG00000177606 PMC9200208__F3 Low-dose tissue plasminogen activator in patients with refractory hypoxia due to presumed microthrombi in pulmonary vasculature in coronavirus disease 2019: A case series and review of the literature ENSG00000122194 PMC10266771__F1 Proposed mechanism for the regulation of NRAS mutation-driven hematopoietic malignancies involves the CBL/JAK2/RAB27B signaling axis ENSG00000041353 ENSG00000188706 ENSG00000110395 PMC9681929__F3 Circular RNAs as emerging regulators in COVID-19 pathogenesis and progression ENSG00000198793 ENSG00000136997 ENSG00000171791 ENSG00000135828 PMC4278301__F1 Regulation of circulating endocannabinoids associated with cancer and metastases in mice and humans ENSG00000138744 ENSG00000117480 ENSG00000173599 ENSG00000006007 PMC7312468__F1 The MNK1/2-eIF4E axis ENSG00000157764 ENSG00000198793 ENSG00000196712 PMC9181879__F1 Natural Products in Preventing Tumor Drug Resistance and Related Signaling Pathways ENSG00000134982 ENSG00000168036 ENSG00000146648 PMC9681929__F2 Circular RNAs as emerging regulators in COVID-19 pathogenesis and progression ENSG00000135655 ENSG00000125107 ENSG00000075420 ENSG00000152377 ENSG00000081189 PMC6800061__F2 TARGETING INFLAMMATION IN METABOLIC SYNDROME ENSG00000277494 ENSG00000226275 ENSG00000130164 ENSG00000042832 ENSG00000162692 PMC6445151__F3 Differential network for the pathway “Signaling by NOTCH1” in the lateral compartment ENSG00000005339 ENSG00000150991 ENSG00000168214 ENSG00000283780 ENSG00000184384 ENSG00000148400 ENSG00000078747 ENSG00000184916 ENSG00000135144 ENSG00000114166 ENSG00000100603 PMC3967171__F2 Sex hormones and SREBP selectively regulate expression of Aldh1 ENSG00000184254 ENSG00000128918 PMC7608746__F1 SPRED proteins and their roles in signal transduction, development, and malignancy ENSG00000166068 PMC6912516__F2 Schematic representation of main ACVR1 signal transduction ENSG00000121989 ENSG00000170365 ENSG00000163914 ENSG00000204217 ENSG00000114739 PMC6445151__F4 The differential network for the pathway “InlA-mediated entry of Listeria monocytogenes into host cells” in neuroblastoma tumors between HR and non-HR patients ENSG00000150991 ENSG00000291971 ENSG00000198561 PMC4010328__F5 TOB1 was involved in regulation of tumor growth and metastasis via the PI3K/PTEN signaling pathway ENSG00000141232 ENSG00000138798 ENSG00000168036 PMC7752859__F15 The immunomodulatory activity of Ligilactobacillus salivarius TUCO-L2 isolated from llama (Lama glama) milk in porcine intestinal epithelial (PIE) cells ENSG00000169248 ENSG00000185187 ENSG00000169245 ENSG00000170458 ENSG00000138755 ENSG00000177606 ENSG00000125538 ENSG00000108700 ENSG00000134070 ENSG00000169429 ENSG00000136869 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC4704494__F3 Chemical–genetic interaction map of small molecules using high‐throughput imaging in cancer cells ENSG00000168036 PMC9589297__F4 Traditional Chinese medicine for hypertrophic scars—A review of the therapeutic methods and potential effects ENSG00000092439 PMC9589297__F5 Traditional Chinese medicine for hypertrophic scars—A review of the therapeutic methods and potential effects ENSG00000105329 ENSG00000168036 ENSG00000168610 PMC6128439__F6 mTOR pathway ENSG00000177169 ENSG00000163435 ENSG00000171105 ENSG00000198793 ENSG00000173599 ENSG00000141564 ENSG00000102104 PMC6674869__F8 Intracellular signaling pathways downstream of p75NTR and TrkA in sensory neurons ENSG00000104321 ENSG00000196689 PMC316957__F9 How ECSIT may participate in Toll/IL-1 signaling ENSG00000102871 ENSG00000082512 ENSG00000172936 ENSG00000130159 ENSG00000175104 ENSG00000127191 PMC4299612__F2 Regulation of Toll-like receptor (TLR) signaling during bacterial lung infections ENSG00000174125 ENSG00000183735 ENSG00000081041 ENSG00000163739 ENSG00000026508 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000083799 ENSG00000150455 ENSG00000276561 PMC2649968__F4 Participation of DNA repair in the response to 5-fluorouracil ENSG00000175054 ENSG00000123415 ENSG00000095002 ENSG00000122512 PMC5548615__F1 Emerging role of PI3K/AKT-mediated epigenetic regulation in cancer ENSG00000132646 ENSG00000140464 PMC5641208__F1 S100A4 in cancer progression and metastasis: A systematic review ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000196154 ENSG00000168036 PMC3375057__F2 Neurotrophins, the ERK MAP kinase signaling cascade, and GSK-3 ENSG00000002330 ENSG00000168036 PMC8043969__F1 Germline Variants that Affect Tumor Progression ENSG00000115524 ENSG00000198793 ENSG00000172543 ENSG00000079432 ENSG00000088256 ENSG00000121879 PMC6800568__F1 Innate immune mechanisms in SLE ENSG00000169245 ENSG00000239732 ENSG00000164430 ENSG00000125538 ENSG00000172936 ENSG00000163687 PMC5581236__F7 SUMOylation Negatively Regulates Angiogenesis by Targeting Endothelial NOTCH Signaling ENSG00000079387 ENSG00000135547 ENSG00000128917 ENSG00000148400 ENSG00000116030 ENSG00000114315 PMC3418056__F5 Postulated interactions between 20-HETE and RAS in the vascular endothelium ENSG00000146648 PMC5412423__F6 Ceramide metabolism in desipramine-pretreated mice undergoing septic cardiomyopathy ENSG00000139624 ENSG00000063176 ENSG00000143753 ENSG00000188611 ENSG00000285281 ENSG00000102172 ENSG00000143418 ENSG00000135587 PMC3197858__F1 Fatty acid synthase as a potential therapeutic target in cancer ENSG00000131473 ENSG00000169710 PMC2592794__F1 Monosodium urate (MSU) crystals activate monocytes via the Toll-like receptor (TLR) pathway and the inflammasome ENSG00000170458 ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC84916__F8 The mechanism of regulation of PLCG2 tyrosine phosphorylation and activation by LAT ENSG00000213658 ENSG00000010810 ENSG00000197943 PMC7895520__F7 Mechanism of the protective effect of spermine against high glucose-induced diabetic podocyte injury ENSG00000198793 ENSG00000284099 ENSG00000057663 PMC11050262__F8 Gene expression changes in GO terms: (A) base excision repair, (B) mismatch repair, and (C) homologous recombination pathways in response to high–THC extract #18 compared to DMSO control in the HT–29 CRC cell line ENSG00000149311 ENSG00000083093 ENSG00000105664 ENSG00000113318 ENSG00000182185 ENSG00000173599 ENSG00000197299 ENSG00000095002 ENSG00000139618 PMC6443116__F7 Localized decidualization in the cycling human endometrium ENSG00000146678 ENSG00000148344 ENSG00000124212 PMC3091668__F4 Putative TLR signal pathway ENSG00000174125 ENSG00000185187 ENSG00000150455 ENSG00000276561 ENSG00000010671 ENSG00000183735 ENSG00000088888 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC3913210__F2 Hedgehog signaling from the primary cilium to the nucleus: an emerging picture of ciliary localization, trafficking and transduction ENSG00000081870 ENSG00000143147 ENSG00000187240 ENSG00000106571 ENSG00000173040 ENSG00000169379 ENSG00000128602 ENSG00000168778 ENSG00000138686 ENSG00000132341 PMC3913210__F1 Hedgehog signaling from the primary cilium to the nucleus: an emerging picture of ciliary localization, trafficking and transduction ENSG00000143147 ENSG00000064309 ENSG00000144857 ENSG00000166813 ENSG00000128602 PMC3091668__F5 Putative TCR signal pathway ENSG00000291603 ENSG00000213658 ENSG00000070831 ENSG00000010810 ENSG00000163599 ENSG00000113263 PMC11987372__F2 Expression and mechanism of action of chemokine family members in PNI ENSG00000162711 ENSG00000168329 ENSG00000107562 ENSG00000081041 ENSG00000143546 ENSG00000163739 ENSG00000163220 ENSG00000198793 ENSG00000162772 ENSG00000121807 ENSG00000121966 ENSG00000108691 ENSG00000143379 ENSG00000108688 ENSG00000136869 ENSG00000172936 ENSG00000128342 ENSG00000100219 ENSG00000161298 ENSG00000164342 PMC3035594__F3 Integrated view of Wnt pathway ENSG00000004975 ENSG00000137713 ENSG00000177606 ENSG00000136997 ENSG00000276920 PMC7870078__F5 Identification of differentially expressed genes involved in amino acid and lipid accumulation of winter turnip rape (Brassica rapa L.) in response to cold stress ENSG00000172482 PMC9530455__F4 mRNA-miRNA networks identify metabolic pathways associated to the anti-tumorigenic effect of thyroid hormone on preneoplastic nodules and hepatocellular carcinoma ENSG00000131096 PMC7771966__F1 Identification of UDP-glucose:glycoprotein glucosyltransferase (UGGT) 1/2 substrates ENSG00000101901 ENSG00000019991 ENSG00000145147 ENSG00000033011 ENSG00000001036 ENSG00000139133 ENSG00000197594 ENSG00000083444 ENSG00000088035 ENSG00000214160 ENSG00000152952 ENSG00000182858 ENSG00000086619 PMC6906582__F1 Toll‐like receptors (TLRs) and their downstream signaling ENSG00000276561 PMC11965705__F1 Important pathways and their functions in pancreatic ductal adenocarcinoma ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC4032125__F7 Molecular Evolution of the Yap/Yorkie Proto-Oncogene and Elucidation of Its Core Transcriptional Program PMC2929006__F5 Genetic basis of kidney cancer: a metabolic disease ENSG00000002330 ENSG00000052795 ENSG00000217128 PMC6906582__F4 Viral RNA sensing proteins and their downstream signaling ENSG00000111331 ENSG00000135828 ENSG00000276561 PMC7291824__F4 Ingenuity Pathway Analysis of gene networks ENSG00000122986 ENSG00000274211 ENSG00000187796 ENSG00000122218 ENSG00000136100 ENSG00000178999 ENSG00000204136 ENSG00000054654 ENSG00000265972 ENSG00000145088 ENSG00000141441 ENSG00000146094 ENSG00000011143 ENSG00000170379 ENSG00000145911 ENSG00000139193 ENSG00000149599 ENSG00000102221 ENSG00000123091 ENSG00000147162 ENSG00000132622 ENSG00000140545 ENSG00000131019 ENSG00000132465 ENSG00000162894 ENSG00000186810 ENSG00000080031 ENSG00000026751 ENSG00000116539 ENSG00000048462 ENSG00000105939 ENSG00000103522 ENSG00000170262 ENSG00000169032 ENSG00000010671 ENSG00000275331 ENSG00000135457 ENSG00000128283 ENSG00000178764 ENSG00000149658 ENSG00000188157 ENSG00000081377 ENSG00000158796 ENSG00000146678 ENSG00000125968 ENSG00000086730 ENSG00000007312 ENSG00000198951 ENSG00000096088 ENSG00000196562 ENSG00000281877 ENSG00000112874 ENSG00000008283 ENSG00000177189 ENSG00000111537 ENSG00000102858 ENSG00000175215 ENSG00000173757 ENSG00000186716 ENSG00000114268 ENSG00000040199 ENSG00000162545 ENSG00000138080 PMC3842494__F8 The proposed role of high CORT levels on the proinflammatory response triggered by LPS and related to MAP kinase–NFKB pathway in rat brain ENSG00000125538 ENSG00000145321 ENSG00000136869 PMC9369058__F6 Spotlight on Exosomal Non-Coding RNAs in Breast Cancer: An In Silico Analysis to Identify Potential lncRNA/circRNA-miRNA-Target Axis ENSG00000196388 ENSG00000111837 ENSG00000198793 ENSG00000139618 PMC3624394__F4 Comparative analysis of NOTCH signaling pathway components in calcium-differentiated 8E6-iHFKs and GSI-treated C-HFKs by qRT-PCR ENSG00000135547 ENSG00000148400 ENSG00000100060 ENSG00000184916 ENSG00000137845 ENSG00000135144 ENSG00000090932 ENSG00000106003 ENSG00000143801 ENSG00000168214 ENSG00000283780 ENSG00000074181 ENSG00000184384 ENSG00000128917 ENSG00000205155 ENSG00000196498 ENSG00000273529 ENSG00000133961 ENSG00000114315 ENSG00000100603 PMC9671940__F2 Growth stimulation expressed gene 2 (ST2): Clinical research and application in the cardiovascular related diseases ENSG00000137033 ENSG00000175104 PMC9107782__F6 Manipulating the Wnt/Beta-catenin signaling pathway to promote anti-tumor immune infiltration into the TME to sensitize ovarian cancer to ICB therapy ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000102312 ENSG00000168036 PMC8396260__F9 Inhibition of Cell Proliferation and Metastasis by Scutellarein Regulating PI3K/Akt/NFKB Signaling through PTEN Activation in Hepatocellular Carcinoma ENSG00000170558 PMC9107782__F1 Manipulating the Wnt/Beta-catenin signaling pathway to promote anti-tumor immune infiltration into the TME to sensitize ovarian cancer to ICB therapy ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000102312 ENSG00000168036 PMC8934553__F7 LECT2 Ameliorates Blood–Retinal Barrier Impairment Secondary to Diabetes Via Activation of the Tie2/Akt/mTOR Signaling Pathway ENSG00000145826 ENSG00000198793 PMC4743122__F1 Schematic illustration of the mechanisms impairing VEGF-A/VEGFR-2 angiogenic signal in SSc ENSG00000151702 ENSG00000112715 PMC2515871__F2 Roles of cis- and trans-Changes in the Regulatory Evolution of Genes in the Gluconeogenic Pathway in Yeast ENSG00000124253 ENSG00000146701 PMC9516650__F1 Liquid biopsy to detect resistance mutations against anti-epidermal growth factor receptor therapy in metastatic colorectal cancer ENSG00000157764 ENSG00000198793 ENSG00000121879 ENSG00000146648 PMC7779046__F2 The ‘Hedgehog Signaling Pathway’ page includes a description of the pathway, links to sub-groups and other related gene groups ENSG00000213658 ENSG00000128602 PMC10922197__F9 Mechanism by which NBP inhibits osteoclastogenesis is demonstrated ENSG00000102575 ENSG00000175104 ENSG00000131196 ENSG00000079999 ENSG00000143387 PMC6586838__F2 Association between miRNAs of interest and their predicted targets in the insulin signaling pathway (A) and Type II diabetes mellitus pathway (B) ENSG00000171105 ENSG00000002330 ENSG00000110395 ENSG00000005882 ENSG00000150907 ENSG00000198793 ENSG00000182759 ENSG00000026103 PMC2810358__F2 Comparative protein profiling reveals minichromosome maintenance (MCM) proteins as novel potential tumor markers for meningiomas ENSG00000092201 ENSG00000108055 ENSG00000054654 ENSG00000139613 ENSG00000073111 ENSG00000095002 PMC7892432__F2 Mechanism of pyroptosis affecting endothelial cells in ALI ENSG00000278718 ENSG00000162711 ENSG00000164430 ENSG00000189403 ENSG00000136869 PMC7892432__F1 Mechanism of pyroptosis affecting alveolar macrophages in ALI ENSG00000278718 ENSG00000162711 ENSG00000164430 ENSG00000189403 ENSG00000172936 ENSG00000136869 PMC8911031__F1 Coenzyme A Restriction as a Factor Underlying Pre-Eclampsia with Polycystic Ovary Syndrome as a Risk Factor ENSG00000101670 ENSG00000174915 ENSG00000169710 ENSG00000114698 ENSG00000143418 ENSG00000139624 ENSG00000063176 ENSG00000188257 ENSG00000165389 ENSG00000153395 ENSG00000177666 ENSG00000156471 ENSG00000163082 PMC8494658__F3 Where are we now? Emerging opportunities and challenges in the management of secondary hyperparathyroidism in patients with non-dialysis chronic kidney disease ENSG00000111012 ENSG00000205221 ENSG00000019186 ENSG00000135929 PMC6434466__F7 Osteopontin (OPN) stimulated monocyte chemoattractant protein 1 (MCP-1) production and migration of monocytes ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC4390087__F5 Beyond Mitophagy: Cytosolic PINK1 as a Messenger of Mitochondrial Health ENSG00000123240 ENSG00000158828 ENSG00000069509 PMC6372909__F1 Human epidermal growth factor receptor targeted inhibitors for the treatment of ovarian cancer ENSG00000113905 ENSG00000109321 ENSG00000163235 ENSG00000124882 ENSG00000113070 ENSG00000138798 ENSG00000198793 PMC4194117__F1 SIRT2 controls the pentose phosphate switch ENSG00000096717 ENSG00000283100 PMC5415203__F6 Kaposi Sarcoma Herpesvirus (KSHV) Latency-Associated Nuclear Antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latency ENSG00000183735 ENSG00000164430 ENSG00000187796 PMC3356999__F1 Fatty acid regulation of hepatic lipid metabolism ENSG00000170522 ENSG00000134824 ENSG00000149485 ENSG00000197977 ENSG00000169710 ENSG00000099194 PMC6803550__F7 Model illustrating metabolic processes ENSG00000198793 ENSG00000173599 ENSG00000154059 ENSG00000081051 PMC5487993__F9 Paraquat hijacks the pentose phosphate pathway to induce oxidative stress and cell death ENSG00000105953 ENSG00000115419 ENSG00000062485 PMC7412275__F2 Entry mechanisms of Old World (OW) and New World (NW) arenaviruses ENSG00000102189 ENSG00000135404 ENSG00000118257 PMC6007949__F6 CD300A promotes tumor progression by PECAM1, ADCY7 and AKT pathway in acute myeloid leukemia ENSG00000261371 ENSG00000198793 ENSG00000291918 PMC3100327__F1 De novo Biosynthesis of Biodiesel by Escherichia coli in Optimized Fed-Batch Cultivation ENSG00000168040 PMC4521418__F3 Brca1 pathway is involved in microglia from hSOD1G93A mice ENSG00000001167 ENSG00000112715 ENSG00000139618 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000111537 ENSG00000134574 ENSG00000101773 ENSG00000115415 ENSG00000134057 ENSG00000132646 ENSG00000164362 ENSG00000095002 ENSG00000123268 PMC2760836__F2 New concepts in herpes simplex virus vaccine development: notes from the battlefield ENSG00000172936 PMC3871878__F2 Hypoxia inducible factor pathway inhibitors as anticancer therapeutics ENSG00000134086 ENSG00000198793 PMC10931690__F9 Diagram depicting the mechanism of neuroprotective effect of siponimod/BAF312 ENSG00000118972 ENSG00000169245 ENSG00000115009 ENSG00000186827 PMC5741702__F2 Localization of the polycystic kidney disease (PKD) proteins, the pathways implicated in its pathogenesis, and putative therapeutic targets ENSG00000198793 ENSG00000173599 ENSG00000096717 ENSG00000130175 ENSG00000089597 PMC6170780__F4 Prediction of antiviral targets [reactions] from single-reaction perturbations in a virus-optimized system for CHIKV, DENV and ZIKV ENSG00000254550 PMC7409333__F1 Sphingolipid metabolic pathway (plus five sphingosine-1-phosphate receptors) ENSG00000167769 ENSG00000100422 ENSG00000198964 ENSG00000143753 ENSG00000119537 ENSG00000078124 ENSG00000148154 ENSG00000285281 ENSG00000113163 PMC5702304__F3 Overview of human TLRs activated by exogenous and endogenous ligands, such as fragmented DNA from necrotic cells; adapted by permission from Macmillan Publishers Ltd, Nature Reviews Gastroenterology and Hepatology, 2006, vol ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000276561 ENSG00000164342 PMC4730344__F4 Induction of DNA repair by EGFR signaling ENSG00000149311 ENSG00000012048 ENSG00000051180 ENSG00000146648 ENSG00000253729 ENSG00000139618 PMC4730344__F2 Cell death pathways after irradiation ENSG00000135446 ENSG00000123374 ENSG00000120868 ENSG00000105810 ENSG00000171791 ENSG00000168040 ENSG00000139687 ENSG00000125968 PMC9370344__F7 Waterlogging Stress Induces Antioxidant Defense Responses, Aerenchyma Formation and Alters Metabolisms of Banana Plants ENSG00000131473 ENSG00000074800 ENSG00000117118 ENSG00000159399 PMC5071566__F8 Modulation of host AKT pathway by L ENSG00000164379 ENSG00000168036 PMC3260274__F5 Tumour Suppressive Function and Modulation of Programmed Cell Death 4 (PDCD4) in Ovarian Cancer PMC4778253__F4 Mesenchymal and endodermal signaling events ENSG00000070193 ENSG00000183691 ENSG00000134245 ENSG00000164690 ENSG00000182580 PMC6949159__F5 KEGG pathway: CELL CYCLE (A) and P53 SIGNALING PATHWAY (B) ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000136997 ENSG00000042286 ENSG00000112378 ENSG00000196470 ENSG00000276876 PMC8896082__F1 Effects of the probiotic cocktail on modulation of the NF-kB and JAK/STAT signaling pathways involved in the inflammatory response in bowel disease model ENSG00000167207 ENSG00000172936 ENSG00000150455 ENSG00000105639 PMC8514763__F3 Non-Coding RNAs Inducing Drug Resistance in Ovarian Cancer: A New Perspective for Understanding Drug Resistance ENSG00000087095 ENSG00000175832 ENSG00000168036 ENSG00000079432 ENSG00000150457 ENSG00000104332 ENSG00000168610 ENSG00000131023 PMC4501477__F4 What’s the Damage? The Impact of Pathogens on Pathways that Maintain Host Genome Integrity ENSG00000149311 ENSG00000175054 ENSG00000163961 ENSG00000112130 PMC12025106__F3 The activated PI3K/Akt/mTOR/c-MYC pathway in metabolic reprogramming to dietary methionine sources PMC4501477__F3 What’s the Damage? The Impact of Pathogens on Pathways that Maintain Host Genome Integrity ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000163961 ENSG00000112130 PMC7312541__F1 Canonical Wnt/Beta-catenin pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC12025106__F1 Helicobacter pylori infection in methionine metabolism PMC8539574__F2 Glycation and Glycosylation in Cardiovascular Remodeling: Focus on Advanced Glycation End Products and O-Linked Glycosylations as Glucose-Related Pathogenetic Factors and Disease Markers ENSG00000100522 ENSG00000147162 ENSG00000198408 PMC7407016__F1 Regulatory circuits driven by liganded ER-alpha for DNA stabilization (A), cell proliferation (B), and fuel supply (C) ENSG00000012048 ENSG00000169047 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC6857900__F3 The Links between FTO and Colon Cancer ENSG00000168610 PMC8192426__F1 Contraction in airway smooth muscle (ASM) ENSG00000167323 ENSG00000163914 PMC9396278__F7 Novel regulated network mediated by downregulation HIF1A-AS2 lncRNA impairs placental angiogenesis by promoting ANGPTL4 expression in preeclampsia ENSG00000167772 PMC6857900__F2 Simplified Version of the Canonical Wnt/ Beta-Catenin Pathway ENSG00000134982 ENSG00000168036 PMC4874655__F3 COLORECTAL CANCER ENSG00000157764 ENSG00000162337 ENSG00000065361 ENSG00000134982 ENSG00000168036 PMC2815016__F4 Activation of the NFKB signaling pathway by farnesol is related to ER stress ENSG00000144895 ENSG00000163734 ENSG00000127191 PMC8313979__F3 Systems-based framework to computationally describe putative transcription factors and signaling pathways regulating glycan biosynthesis ENSG00000262102 ENSG00000173575 ENSG00000131446 ENSG00000176597 ENSG00000111728 ENSG00000020633 ENSG00000140044 ENSG00000073849 ENSG00000143578 ENSG00000081189 ENSG00000171310 ENSG00000198162 ENSG00000111962 ENSG00000151702 ENSG00000147408 ENSG00000122863 ENSG00000152127 ENSG00000196371 ENSG00000137265 ENSG00000113532 ENSG00000180549 PMC2815016__F3 Farnesol induces ER stress and activation of the unfolded protein response ENSG00000128272 ENSG00000144895 ENSG00000155660 ENSG00000100219 ENSG00000127191 PMC8313979__F2 Systems-based framework to computationally describe putative transcription factors and signaling pathways regulating glycan biosynthesis ENSG00000073849 PMC6966677__F6 Cell proliferation and metastasis of gastric cancer by modulation of VGLL1 expression and activity ENSG00000102243 ENSG00000138795 ENSG00000197905 ENSG00000168036 ENSG00000100985 ENSG00000196628 PMC7957263__F1 Signalling pathways DKK4 involved in different kinds of cancer ENSG00000134982 ENSG00000104371 ENSG00000168036 PMC8688647__F6 Network map of Elabela signaling pathway in physiological and pathological conditions ENSG00000087245 ENSG00000108691 ENSG00000291748 ENSG00000171791 ENSG00000100985 ENSG00000108821 ENSG00000121879 ENSG00000142082 ENSG00000164305 PMC8688647__F5 Network map of Elabela signaling pathway in physiological and pathological conditions ENSG00000141480 PMC8688647__F2 Network map of Elabela signaling pathway in physiological and pathological conditions ENSG00000175206 ENSG00000148346 ENSG00000105329 ENSG00000198793 ENSG00000143839 ENSG00000171791 ENSG00000142082 ENSG00000121879 ENSG00000164305 ENSG00000119681 ENSG00000120937 ENSG00000150782 ENSG00000108691 ENSG00000111537 ENSG00000171992 ENSG00000133110 ENSG00000092054 ENSG00000130234 ENSG00000108821 ENSG00000112115 ENSG00000116218 ENSG00000123268 PMC8688647__F1 Network map of Elabela signaling pathway in physiological and pathological conditions ENSG00000162711 ENSG00000105329 ENSG00000198793 ENSG00000134363 ENSG00000108443 ENSG00000158517 ENSG00000116701 ENSG00000121879 ENSG00000150782 ENSG00000164458 ENSG00000204673 ENSG00000108821 ENSG00000184344 PMC8688647__F4 Network map of Elabela signaling pathway in physiological and pathological conditions ENSG00000125538 ENSG00000198793 ENSG00000171791 PMC6744284__F7 Differentially expressed transcripts in FSGS were enriched in the JAK-STAT pathway in the glomeruli ENSG00000111537 ENSG00000170458 ENSG00000198793 PMC8688647__F3 Network map of Elabela signaling pathway in physiological and pathological conditions ENSG00000143799 ENSG00000188486 ENSG00000105329 ENSG00000198793 ENSG00000108443 ENSG00000164305 ENSG00000258102 ENSG00000187840 ENSG00000057663 ENSG00000175054 ENSG00000108691 ENSG00000149554 ENSG00000145782 PMC6744284__F6 Differentially expressed transcripts in FSGS were enriched in the JAK-STAT pathway in the tubulointerstitium ENSG00000111537 ENSG00000002330 ENSG00000197296 ENSG00000198793 ENSG00000177606 ENSG00000164342 PMC6149884__F1 VAV1 signaling in lymphocytes ENSG00000148400 ENSG00000163914 ENSG00000141968 PMC8079762__F1 Targeting Solid Tumors With BTK Inhibitors ENSG00000002330 ENSG00000010671 PMC4281466__F1 TGF-beta signaling pathways ENSG00000023734 ENSG00000163914 PMC6397804__F2 Poly(I:C)-toll-like receptor 3 signaling pathway and polarization of mesenchymal stem cells ENSG00000178860 ENSG00000136869 ENSG00000164342 PMC11510049__F9 Comparative analysis of transcript and protein abundance in the HSP60-HSP70-TLR2/4 signaling pathway in children with severe malarial anemia ENSG00000170458 ENSG00000172005 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000112149 ENSG00000175104 PMC9178347__F2 Critical metabolic pathways and SAD/FADs, WRI1s, and DGATs cooperate for high-oleic acid oil production in developing oil tea (Camellia oleifera) seeds ENSG00000047597 PMC3926427__F1 FGF/FGFR signaling pathway ENSG00000138798 ENSG00000198793 PMC3376383__F2 Growth Control by Committee – Intercellular Junctions, Cell Polarity, and the Cytoskeleton Regulate Hippo Signaling ENSG00000126016 ENSG00000130545 ENSG00000132849 ENSG00000072415 PMC7880612__F1 Molecular tracing of prostate cancer lethality ENSG00000125398 ENSG00000104960 ENSG00000118785 ENSG00000160182 ENSG00000124766 ENSG00000026508 ENSG00000139352 ENSG00000116977 PMC6443331__F5 AMPK-dependent anticancer activities of honokiol in ovarian cancer cells ENSG00000198793 ENSG00000100985 PMC9437103__F3 Exercise training maintains cardiovascular health: signaling pathways involved and potential therapeutics ENSG00000179862 ENSG00000177169 ENSG00000083290 ENSG00000285109 ENSG00000198793 PMC4106164__F1 PD-L1 expression and tumor-infiltrating lymphocytes ENSG00000102962 ENSG00000159128 ENSG00000027697 ENSG00000049768 PMC5609723__F2 Aryl hydrocarbon receptor-mediated hepatotoxicity is a cumulative response to the overall burden of multiple disrupted pathways rather than a single adverse effect ENSG00000105550 ENSG00000106546 PMC9437103__F2 Exercise training maintains cardiovascular health: signaling pathways involved and potential therapeutics ENSG00000140443 PMC8236548__F1 Other side of the coin: dissecting molecular mechanisms behind hereditary breast cancer in search of therapeutic opportunities ENSG00000149311 ENSG00000175054 ENSG00000083093 ENSG00000123374 ENSG00000139618 PMC9315891__F3 Exploring Yeast Diversity to Produce Lipid-Based Biofuels from Agro-Forestry and Industrial Organic Residues ENSG00000197713 ENSG00000047597 ENSG00000158125 PMC9315891__F2 Exploring Yeast Diversity to Produce Lipid-Based Biofuels from Agro-Forestry and Industrial Organic Residues ENSG00000198670 ENSG00000026103 ENSG00000158125 PMC7710690__F2 PD-1 and PD-L1 interactions and mechanism of T cell inhibition ENSG00000291603 ENSG00000134982 ENSG00000156127 ENSG00000198793 ENSG00000124181 PMC3338748__F1 High-Throughput Sequencing of mGluR Signaling Pathway Genes Reveals Enrichment of Rare Variants in Autism ENSG00000005882 ENSG00000197283 ENSG00000198793 ENSG00000198576 ENSG00000162105 ENSG00000292254 ENSG00000196712 PMC8229352__F1 Multifaceted Functions of Autophagy in Breast Cancer Development and Treatment ENSG00000177169 ENSG00000198793 ENSG00000144848 ENSG00000070540 ENSG00000145782 ENSG00000057663 PMC8229352__F5 Multifaceted Functions of Autophagy in Breast Cancer Development and Treatment ENSG00000148400 ENSG00000291971 ENSG00000198793 ENSG00000026508 ENSG00000168036 ENSG00000168610 ENSG00000146648 ENSG00000125084 PMC8001024__F1 Cohesin cycle in human cells ENSG00000171320 ENSG00000166851 ENSG00000274473 ENSG00000141446 PMC5855797__F6 Signal transduction in relation to the IR ENSG00000005882 ENSG00000169047 ENSG00000121853 PMC2948497__F6 cDNA Microarray Gene Expression Profiling of Hedgehog Signaling Pathway Inhibition in Human Colon Cancer Cells ENSG00000168209 ENSG00000178999 ENSG00000131747 ENSG00000145386 ENSG00000167900 ENSG00000124762 ENSG00000117399 ENSG00000094804 ENSG00000134057 ENSG00000100479 ENSG00000123374 ENSG00000177084 ENSG00000282899 ENSG00000175305 PMC5855797__F2 GPCR agonism bias towards insulin receptor activation ENSG00000169047 ENSG00000100985 ENSG00000135577 PMC8561165__F1 Kynurenine pathway activation and deviation to anthranilic and kynurenic acid in fibrosing chronic graft-versus-host disease ENSG00000205221 ENSG00000138755 PMC8561165__F3 Kynurenine pathway activation and deviation to anthranilic and kynurenic acid in fibrosing chronic graft-versus-host disease ENSG00000150782 ENSG00000138755 PMC9486121__F3 Key signal transduction pathways and crosstalk in cancer: Biological and therapeutic opportunities ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC9486121__F2 Key signal transduction pathways and crosstalk in cancer: Biological and therapeutic opportunities ENSG00000198793 PMC8126045__F1 Lytic Viral Replication and Co-Infections in the Oncogenesis and Immune Control of the Epstein–Barr Virus ENSG00000139193 ENSG00000117091 ENSG00000102158 ENSG00000113263 ENSG00000124181 PMC7199655__F1 Coupled-clock pacemaker system of the sinoatrial node PMC10571979__F8 Norrin signals through DVL1 to stimulate barrier properties ENSG00000107404 ENSG00000281324 ENSG00000162337 ENSG00000106025 ENSG00000184113 ENSG00000174804 PMC9659209__F1 Histone Deacetylase Functions in Gastric Cancer: Therapeutic Target? ENSG00000196591 ENSG00000026508 ENSG00000133422 PMC8243427__F2 MicroRNAs: emerging driver of cancer perineural invasion ENSG00000128191 ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC8576699__F6 Synergistic effect of chidamide and venetoclax on apoptosis in acute myeloid leukemia cells and its mechanism ENSG00000123374 ENSG00000168610 PMC4046179__F5 98 proteins that showed significant changes in oxidation levels with HFHS diet were subjected to IPA ENSG00000143252 ENSG00000090402 ENSG00000073578 ENSG00000179091 ENSG00000117118 ENSG00000126267 PMC6008255__F1 Different Wnt signaling pathways ENSG00000281324 ENSG00000162337 ENSG00000100592 ENSG00000134982 ENSG00000163914 ENSG00000112655 ENSG00000168036 ENSG00000167074 PMC3271860__F7 THE ROLE OF IGF-1 SIGNALING PATHWAY IN CISPLATIN-RESISTANT LUNG CANCER CELLS ENSG00000140443 PMC3877826__F9 Model of Interaction with the b-Dependent Developmental Control Pathway.(A) Filamentous growth is triggered by bE/bW-dependent induction of rbf1 expression ENSG00000172409 ENSG00000180644 PMC2654411__F6 Time-course Comparison of Xenobiotic Activators of CAR and PPARA in Mouse Liver ENSG00000139193 ENSG00000120837 ENSG00000038002 ENSG00000076003 ENSG00000064300 ENSG00000008056 ENSG00000108061 ENSG00000166508 ENSG00000276043 ENSG00000150782 ENSG00000073060 ENSG00000133110 ENSG00000122756 ENSG00000167325 ENSG00000125538 ENSG00000115942 ENSG00000185591 ENSG00000168310 ENSG00000146648 ENSG00000105825 PMC7432002__F3 Interaction among MyD88, Toll-like receptor 4, IL-1 receptor signalling pathway in the innate immune response to tick-borne pathogens that could positively control the IFNG secretion; meanwhile, there is lack of IL-18 and IL-12 due to MAS ENSG00000150782 ENSG00000115008 ENSG00000111537 ENSG00000173757 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000168811 PMC10982647__F8 Metabolic rewiring mechanisms in drug-resistant breast cancer cells ENSG00000092621 ENSG00000126457 ENSG00000169710 PMC8328898__F2 Membrane-Associated Mucins of the Human Ocular Surface in Health and Disease ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC7432002__F5 Interaction between IL-1B and I-kB kinase/NF-kB signalling pathway, which have positive activation of Nuclear Factor Kappa B Subunit 1 ENSG00000104689 ENSG00000096996 ENSG00000150782 ENSG00000104365 ENSG00000109320 ENSG00000125538 ENSG00000168040 ENSG00000105639 ENSG00000112115 ENSG00000064012 ENSG00000026103 PMC8824439__F1 CCM in Mtb ENSG00000122966 ENSG00000171444 ENSG00000172005 PMC2654411__F3 Time-course Comparison of Xenobiotic Activators of CAR and PPARA in Liver ENSG00000138115 PMC3271860__F3 IGF-1 SIGNALING PATHWAY IN CISPLATIN-RESISTANT LUNG CANCER CELLS ENSG00000281324 ENSG00000167768 ENSG00000134215 ENSG00000124107 ENSG00000112818 ENSG00000176058 ENSG00000057294 ENSG00000122194 ENSG00000171388 ENSG00000163631 ENSG00000242265 ENSG00000150782 ENSG00000272398 ENSG00000197386 ENSG00000113263 ENSG00000139687 ENSG00000126458 ENSG00000089169 ENSG00000106066 ENSG00000147044 ENSG00000109061 ENSG00000169554 ENSG00000134815 ENSG00000165891 ENSG00000100448 ENSG00000079257 ENSG00000134363 ENSG00000073910 ENSG00000111450 ENSG00000000971 ENSG00000168938 ENSG00000163661 ENSG00000171033 ENSG00000110693 ENSG00000136603 ENSG00000115648 ENSG00000010810 ENSG00000111052 PMC7432002__F4 Interaction between MyD88 and JAK-STAT pathway, linked to IFNA; this interaction is mediated by suppressors of cytokine signalling 3, SOCS family proteins which are part of a classical negative feedback system regulating cytokine signal transduction ENSG00000188379 ENSG00000134070 ENSG00000172936 ENSG00000120235 ENSG00000186803 ENSG00000234829 ENSG00000105639 ENSG00000147885 ENSG00000120242 ENSG00000214042 ENSG00000137080 PMC8888851__F1 Coping With Stress: The Mitokine GDF-15 as a Biomarker of COVID-19 Severity ENSG00000111537 ENSG00000130234 ENSG00000130513 PMC7277837__F13 Hypothesized pathway for the production of prokaryotic glycolipids in C ENSG00000069482 ENSG00000173599 ENSG00000198670 ENSG00000026103 PMC7664215__F2 Bioactivities and possible mechanisms of pterostilbene ENSG00000087245 ENSG00000291971 ENSG00000125538 ENSG00000198793 ENSG00000100985 ENSG00000168610 PMC8450498__F1 Structural Analysis of SARS-CoV-2 ORF8 Protein: Pathogenic and Therapeutic Implications ENSG00000171246 ENSG00000116406 ENSG00000127452 ENSG00000169972 ENSG00000079150 ENSG00000184277 ENSG00000139269 ENSG00000150093 ENSG00000137563 ENSG00000168615 ENSG00000177663 ENSG00000105223 ENSG00000134901 ENSG00000104368 ENSG00000175895 ENSG00000033100 ENSG00000123989 ENSG00000119655 ENSG00000171004 ENSG00000152952 PMC8752802__F6 IFNG signaling integrity in colorectal cancer immunity and immunotherapy ENSG00000169245 ENSG00000115415 ENSG00000138755 ENSG00000027697 PMC8752802__F3 IFNG signaling integrity in colorectal cancer immunity and immunotherapy ENSG00000111537 ENSG00000065000 ENSG00000027697 PMC9234286__F2 Insight Into Rho Kinase Isoforms in Obesity and Energy Homeostasis ENSG00000067900 PMC9234286__F1 Insight Into Rho Kinase Isoforms in Obesity and Energy Homeostasis ENSG00000105550 PMC8752802__F1 IFNG signaling integrity in colorectal cancer immunity and immunotherapy ENSG00000169245 ENSG00000159128 ENSG00000111537 ENSG00000138755 ENSG00000027697 PMC7158223__F1 Post-transcriptional mechanisms influence proteome content ENSG00000155506 ENSG00000198793 PMC7709131__F3 Complement functions in the context of cancer ENSG00000163661 ENSG00000117322 ENSG00000026103 PMC7709131__F1 Complement system schematic summary ENSG00000291559 ENSG00000196352 ENSG00000117335 ENSG00000166278 ENSG00000236625 PMC12071759__F1 TAM metabolization pathway ENSG00000165841 ENSG00000140505 ENSG00000130649 ENSG00000244474 ENSG00000140465 PMC7158223__F2 Post-transcriptional regulation of stem cell identity under conditions of stress ENSG00000284774 ENSG00000128272 ENSG00000100219 PMC9491571__F2 Over- and under-expressed genes are highlighted in WNT signaling pathway ENSG00000087095 ENSG00000095739 ENSG00000134982 ENSG00000147869 ENSG00000113558 ENSG00000148175 ENSG00000166278 ENSG00000185269 PMC2533280__F1 Wnt, Activin, and BMP Signaling Regulate Distinct Stages in the Developmental Pathway from Embryonic Stem Cells to Blood ENSG00000166823 ENSG00000147869 ENSG00000120094 PMC6741067__F14 The signaling cascade activated by the CaSR that induces the arrival of ZO-2 to TJs ENSG00000126562 ENSG00000173599 ENSG00000036828 PMC3174204__F6 Conserved Regulation of p53 Network Dosage by MicroRNA–125b Occurs through Evolving miRNA–Target Gene Pairs ENSG00000149311 ENSG00000175054 ENSG00000002330 ENSG00000180228 PMC2242750__F1 Schematic representation of GADS-related signaling in T cells ENSG00000033327 ENSG00000213658 ENSG00000113263 ENSG00000124181 PMC4185231__F6 TLR2-dependent activation of Beta-catenin pathway in dendritic cells induces regulatory responses and attenuates autoimmune inflammation ENSG00000128918 ENSG00000049768 PMC9024760__F1 Cell Culture Media, Unlike the Presence of Insulin, Affect Alpha-Synuclein Aggregation in Dopaminergic Neurons ENSG00000198793 PMC11279058__F2 Mycoplasma hyopneumoniae generates immune evasion by modulating the host immune system ENSG00000125538 ENSG00000136869 ENSG00000100219 PMC3423339__F7 BMP9 induces EphrinB2 expression in endothelial cells through an Alk1-BMPRII/ActRII-ID1/ID3-dependent pathway: Implications for Hereditary Hemorrhagic Telangiectasia Type II ENSG00000168214 ENSG00000283060 ENSG00000125968 PMC3935825__F1 Accurate measurement of nicotinamide adenine dinucleotide (NAD+) with high-performance liquid chromatography ENSG00000105835 ENSG00000123572 PMC4580256__F1 PI3K pathway inhibitors: potential prospects as adjuncts to vaccine immunotherapy for glioblastoma ENSG00000198793 PMC9317725__F1 Microbial Poly-Gamma-Glutamic Acid (Gamma-PGA) as an Effective Tooth Enamel Protectant ENSG00000039537 PMC7070543__F9 Schematic presentation of erinacine A prevention against MPP+-induced neurotoxicity via either induction of the p-PAK1/cdc42/PI3K/AKT/LIMK2 cell survival pathways or the reduction of the IRE1A/TRAF2/ASK1/GADD45/p21 cell death pathway ENSG00000070831 ENSG00000149269 ENSG00000127191 ENSG00000182541 PMC8529123__F3 MCM3AP-AS1: An Indispensable Cancer-Related LncRNA ENSG00000113140 ENSG00000164916 PMC6064744__F2 Schematic representation of cellular mechanisms possibly implicated in miRNA dysregulation in prion diseases ENSG00000111701 ENSG00000160710 ENSG00000113360 PMC8529123__F2 MCM3AP-AS1: An Indispensable Cancer-Related LncRNA ENSG00000117724 ENSG00000079387 ENSG00000128989 ENSG00000137273 ENSG00000135446 ENSG00000129514 PMC5529928__F1 CXCL12/CXCR4 signaling and related pathways in HCC progression ENSG00000107562 ENSG00000121966 PMC6099188__F1 Bile acids are synthesized in the liver from cholesterol by two metabolic pathways known as the neutral (or classical) and the acidic (alternative) pathways ENSG00000276559 ENSG00000167910 ENSG00000180432 ENSG00000115271 ENSG00000135929 PMC7052306__F1 Activity-dependent synaptic plasticity at the Drosophila larval NMJ PMC4790094__F2 Divalent cation signaling in immune cells ENSG00000092439 ENSG00000102158 ENSG00000186716 ENSG00000168610 PMC4879098__F1 Lysosomal–autophagy pathway ENSG00000003056 ENSG00000084774 PMC5336271__F4 Site-specific gene expression profiling as a novel strategy for unravelling keloid disease pathobiology ENSG00000099985 ENSG00000242689 ENSG00000168036 ENSG00000141052 ENSG00000112715 ENSG00000006062 ENSG00000104408 ENSG00000168610 ENSG00000166147 ENSG00000276561 ENSG00000122025 ENSG00000141867 ENSG00000124216 ENSG00000116132 ENSG00000136997 ENSG00000141753 ENSG00000180543 ENSG00000172057 ENSG00000154188 ENSG00000128602 PMC5520491__F1 Classical and new Wnt/Beta-catenin pathway canonical and non-canonical pathways ENSG00000157933 ENSG00000134982 ENSG00000163914 ENSG00000177606 PMC7792426__F7 Defining the Cardiac Fibroblast Secretome in a Fibrotic Microenvironment ENSG00000167779 ENSG00000115461 ENSG00000115009 PMC4999106__F2 Main components of innate immune system in epidermis and their role in atopic dermatitis (AD) ENSG00000091592 ENSG00000106100 PMC4907392__F5 Network computed by Xtalk for crosstalk from the Hippo signaling pathway (A) to the TGFB signaling pathway (B) ENSG00000018408 PMC7876357__F5 Hyaluronan, Transforming Growth Factor B, and Extra Domain A-Fibronectin: A Fibrotic Triad ENSG00000149311 ENSG00000095739 ENSG00000291971 ENSG00000163914 ENSG00000172936 ENSG00000136869 ENSG00000105698 ENSG00000146648 PMC4907392__F4 Paths used to facilitate literature validation ENSG00000177606 ENSG00000185591 ENSG00000113494 PMC7957049__F2 Wnt signaling pathway activation and inhibition ENSG00000134982 ENSG00000168036 PMC3701138__F1 Main branches ofWnt signalling pathways in neuronal development ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000170558 ENSG00000163914 ENSG00000168036 PMC4907392__F6 Crosstalk network constructed by Xtalk from the NFKB Pathway (A) to the Neurotrophin Pathway (B) using the KEGG-family network ENSG00000177606 PMC6166714__F7 IRAK4 and MyD88-dependent TLR signaling ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000184216 PMC3425527__F1 Hedgehog signalling ENSG00000128602 PMC7851346__F8 URA-mediated EAE Mitigation by Directly Targeting Aryl Hydrocarbon Receptor ENSG00000164400 ENSG00000106546 PMC5015539__F2 Restoring immune tolerance in neuromyelitis optica ENSG00000177455 ENSG00000272398 ENSG00000026508 PMC8038143__F5 Link between chemoresistance and MMP-7 shedding of Fas ligand ENSG00000149311 ENSG00000175054 ENSG00000168040 ENSG00000026103 PMC8369429__F2 Peptides that immunoactivate the tumor microenvironment ENSG00000089692 ENSG00000181847 PMC7763502__F1 Effect of Brassicaceae bioactives compounds upon the transcription of genes related with inflammation ENSG00000175793 ENSG00000136869 ENSG00000079999 PMC5393410__F3 Cancer Transcriptome Dataset Analysis: Comparing Methods of Pathway and Gene Regulatory Network-Based Cluster Identification ENSG00000140992 ENSG00000274211 ENSG00000112576 ENSG00000070193 ENSG00000134460 ENSG00000124126 ENSG00000102678 ENSG00000100385 ENSG00000213658 ENSG00000163558 ENSG00000276870 ENSG00000100078 ENSG00000164400 ENSG00000138795 ENSG00000117215 ENSG00000119535 ENSG00000147168 ENSG00000137070 ENSG00000197461 ENSG00000138378 ENSG00000105397 ENSG00000140285 ENSG00000146648 ENSG00000115145 ENSG00000168685 ENSG00000070388 ENSG00000019991 ENSG00000120833 ENSG00000185634 ENSG00000033327 ENSG00000288174 ENSG00000103522 ENSG00000166484 ENSG00000118971 ENSG00000121879 ENSG00000142166 ENSG00000187980 ENSG00000184381 ENSG00000145623 ENSG00000122756 ENSG00000292373 ENSG00000128052 ENSG00000113263 ENSG00000171105 ENSG00000137673 ENSG00000081237 ENSG00000174804 ENSG00000137193 ENSG00000105639 ENSG00000168610 ENSG00000160691 ENSG00000162594 ENSG00000128272 ENSG00000102466 ENSG00000115415 ENSG00000135446 ENSG00000173757 ENSG00000010810 ENSG00000177606 ENSG00000156427 ENSG00000134853 ENSG00000243646 ENSG00000171608 ENSG00000114279 PMC9228816__F2 Beyond Moco Biosynthesis―Moonlighting Roles of MoaE and MOCS2 ENSG00000142192 ENSG00000124217 ENSG00000164172 ENSG00000139531 ENSG00000158125 PMC8099739__F2 VB10, a new blood biomarker for differential diagnosis and recovery monitoring of acute viral and bacterial infections ENSG00000136999 ENSG00000111537 ENSG00000187608 ENSG00000115267 ENSG00000168036 PMC10552298__F1 , Hypothetical VOC production pathway originated from lipid peroxidation of membrane lipids PMC3507272__F1 Schematic diagram showing the RAS-MAPK signal transduction pathway ENSG00000157764 PMC8256158__F7 Early p38 Activation Regulated by MKP-1 Is Determinant for High Levels of IL-10 Expression Through TLR2 Activation ENSG00000136869 ENSG00000185591 ENSG00000168610 PMC3430113__F4 Schematic depicting a central role for transforming growth factor (TGF)B1 signaling in osteoclastogenesis and immune dysregulation of osteolytic Langerhans cell histiocytosis (LCH) ENSG00000105329 ENSG00000173599 ENSG00000169710 ENSG00000198670 ENSG00000049768 ENSG00000168610 PMC6004768__F1 Defective identified pathways in immunodeficiencies predisposing to high susceptility to Epstein–Barr virus (EBV)-driven B-cell lymphoproliferative diseases ENSG00000139193 ENSG00000102879 ENSG00000117091 ENSG00000102158 ENSG00000171793 ENSG00000113263 ENSG00000204520 PMC1410746__F3 Genmapp view of the epidermal growth factor (EGF) signaling pathway ENSG00000167941 ENSG00000197971 ENSG00000138798 ENSG00000146648 PMC4454399__F2 Top Ingenuity Pathway Analysis (IPA) interactome derived from transcriptional regulators found in the Vesiclepedia database ENSG00000196531 ENSG00000065978 ENSG00000181163 ENSG00000111530 ENSG00000183684 ENSG00000167771 ENSG00000175792 ENSG00000146676 PMC7876795__F3 Alternative signaling activation induced FGFR-TKI resistance ENSG00000065361 ENSG00000198793 ENSG00000146648 ENSG00000182580 PMC6480527__F10 Model of the Nrf2-mediated oxidative stress response pathway in bovine granulosa cells under moderate oxidative stress conditions and under antioxidant (quercetin) supplementation ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC4937204__F1 cGMP-PKG signalling in the cardiomyocyte ENSG00000285109 ENSG00000096088 ENSG00000117152 ENSG00000116741 ENSG00000137672 PMC5893408__F1 Sphingosine-1-phosphate receptors and innate immunity ENSG00000163914 ENSG00000170989 ENSG00000180739 ENSG00000213694 ENSG00000125910 ENSG00000267534 PMC9204905__F6 Hypermethylation of TMEM240 predicts poor hormone therapy response and disease progression in breast cancer ENSG00000108786 ENSG00000140505 ENSG00000213759 ENSG00000197408 ENSG00000130649 ENSG00000173597 ENSG00000173610 ENSG00000140465 ENSG00000138115 ENSG00000132196 ENSG00000196502 ENSG00000165841 ENSG00000244474 ENSG00000160870 PMC11010261__F1 YAP/TAZ‐TEAD signalling axis: A new therapeutic target in malignant pleural mesothelioma ENSG00000186575 ENSG00000274429 ENSG00000291971 ENSG00000163914 ENSG00000197905 ENSG00000114978 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC6117460__F1 A Retinoic Acid Signaling Pathway to Promote ProliferationRetinoic acid, acting via HIF1A and VEGF, is necessary for S-phase re-entry of NSPCs ENSG00000135446 ENSG00000105810 ENSG00000112715 PMC11544849__F4 Avian Models for Human Carcinogenesis—Recent Findings from Molecular and Clinical Research ENSG00000138798 ENSG00000168036 PMC8485144__F3 Molecular Profiling of Spermatozoa Reveals Correlations between Morphology and Gene Expression: A Novel Biomarker Panel for Male Infertility ENSG00000183914 ENSG00000285109 ENSG00000112562 ENSG00000196793 ENSG00000167074 ENSG00000087586 ENSG00000109654 ENSG00000183273 ENSG00000134871 ENSG00000119681 ENSG00000110693 ENSG00000182175 ENSG00000196557 ENSG00000137166 ENSG00000164362 ENSG00000185532 ENSG00000131018 ENSG00000116191 ENSG00000072609 PMC3999155__F6 HSCARG Negatively Regulates the Cellular Antiviral RIG-I Like Receptor Signaling Pathway by Inhibiting TRAF3 Ubiquitination via Recruiting OTUB1 ENSG00000183735 ENSG00000088888 ENSG00000131323 PMC2670022__F1 Pharmacological targeting of the serotonergic system for the treatment of obesity ENSG00000198576 ENSG00000115138 ENSG00000166603 PMC2966096__F7 A hypothetical model of PAR-1 and PAR-2 activation by coagulation proteases when either EPCR or an unknown FX/FXa receptor is occupied by natural ligands ENSG00000134982 ENSG00000173599 PMC7031348__F2 Inflammation and muscle protein turnover ENSG00000169047 ENSG00000168610 PMC10381408__F4 Compound K Production: Achievements and Perspectives ENSG00000197429 ENSG00000169299 PMC10381408__F3 Compound K Production: Achievements and Perspectives ENSG00000180210 ENSG00000187118 ENSG00000139687 PMC8856628__F1 Mechanism of action of GEM in PDAC treatment ENSG00000167325 ENSG00000158825 ENSG00000129187 PMC2891859__F1 General overview of BDNF and GDNF signaling mechanisms ENSG00000010810 ENSG00000163914 ENSG00000171791 PMC7016420__F3 Metabolic reprogramming of HSC ENSG00000125166 ENSG00000172005 ENSG00000166123 PMC6511648__F1 LSD1–NOTCH–ASCL1 Axis in Small Cell Lung Cancer (SCLC) ENSG00000084093 ENSG00000148400 ENSG00000114315 ENSG00000139352 PMC5818364__F2 Acyl-DHAP pathway of ether lipid synthesis ENSG00000018510 ENSG00000198670 ENSG00000116906 ENSG00000197601 ENSG00000026103 PMC3632562__F4 PAK1 Protein Expression in the Auditory Cortex of Schizophrenia Subjects ENSG00000106683 ENSG00000070831 ENSG00000149269 PMC1782125__F2 Signal transduction of TNFRI ENSG00000226275 ENSG00000102871 ENSG00000173039 ENSG00000111321 ENSG00000168040 ENSG00000127191 PMC4779661__F3 Relationship between cellular fatty acid (FA) metabolic pathways and observed associations of FAs and enzyme acitivity estimates (EAEs) with colorectal adenomas ENSG00000170522 ENSG00000099194 ENSG00000026103 PMC3230512__F1 Model showing the various molecular components associated with the store-operated calcium entry pathway ENSG00000144935 ENSG00000167323 ENSG00000293604 PMC6136097__F1 Current putative prognostic biomarkers in glioblastoma ENSG00000170430 PMC8074247__F10 Analysis of LAGEs Family Gene Signature and Prognostic Relevance in Breast Cancer ENSG00000149311 ENSG00000175054 ENSG00000019991 ENSG00000066926 ENSG00000134013 ENSG00000111837 ENSG00000164362 ENSG00000121966 PMC8892134__F1 Targeting the IGF/PI3K/mTOR pathway and AXL/YAP1/TAZ pathways in primary bone cancer ENSG00000167601 ENSG00000171105 ENSG00000163914 ENSG00000143322 ENSG00000150457 ENSG00000168610 ENSG00000131023 ENSG00000140443 PMC11641605__F6 Crosstalk of ECM and hypoxia in the Hippo signaling pathway ENSG00000129474 ENSG00000126016 ENSG00000163914 ENSG00000139926 ENSG00000150457 ENSG00000132849 ENSG00000131023 ENSG00000089225 ENSG00000178568 PMC11641605__F5 Hypoxia regulates intracellular signaling through multiple mechanisms ENSG00000163914 ENSG00000131023 PMC3529674__F5 MyD88-independent TLR signaling ENSG00000183735 ENSG00000136869 PMC11641605__F3 Intracellular signaling regulation of the ECM signal transmission ENSG00000150457 ENSG00000160293 ENSG00000131023 PMC5484492__F5 Meta-analysis of miRNA expression profiles for prostate cancer recurrence following radical prostatectomy ENSG00000171105 ENSG00000169756 ENSG00000164327 ENSG00000129514 ENSG00000196396 ENSG00000168610 ENSG00000197702 ENSG00000149534 ENSG00000136997 ENSG00000150907 ENSG00000291905 ENSG00000037280 ENSG00000102104 PMC5484492__F4 microRNAs in cancer ENSG00000149311 ENSG00000135838 ENSG00000134982 ENSG00000136997 ENSG00000124766 ENSG00000026508 ENSG00000026103 PMC9583386__F1 Farnesoid-X receptor as a therapeutic target for inflammatory bowel disease and colorectal cancer ENSG00000177575 ENSG00000162711 ENSG00000118520 PMC8882121__F6 Olfactomedin-4 improves cutaneous wound healing by promoting skin cell proliferation and migration through POU5F1/OCT4 and ESR1 signalling cascades ENSG00000182718 ENSG00000142627 ENSG00000105329 ENSG00000176014 ENSG00000165280 ENSG00000163453 ENSG00000090776 ENSG00000117707 ENSG00000141564 ENSG00000129219 ENSG00000006451 ENSG00000130402 ENSG00000123374 ENSG00000141367 PMC4331664__F5 The metabolic pathways of Mtb that interconnect glycogen, Tre and other carbohydrates ENSG00000111837 ENSG00000172005 PMC2802426__F1 Molecular mechanisms that regulate ionotropic glutamate receptor distribution during hippocampal mGluR-LTD induction and expression ENSG00000198576 PMC7040165__F2 Controlling pluripotency using small molecule inhibitors and growth factors ENSG00000164736 ENSG00000143768 ENSG00000128342 ENSG00000136826 PMC7040165__F1 Extrinsic signaling pathways governing stemness of pluripotent stem cells ENSG00000156574 ENSG00000128342 PMC2802426__F2 Schematic model of molecular mechanisms underlying regulation of gene transcription and protein translation during mGluR-LTD in postsynaptic neurons of hippocampal CA3-CA1 synapses ENSG00000291971 ENSG00000135446 ENSG00000138798 ENSG00000198793 ENSG00000284161 ENSG00000198576 ENSG00000167658 PMC7916426__F1 BA synthesis and transport pathway ENSG00000160867 ENSG00000167910 ENSG00000173599 ENSG00000081923 PMC8430485__F2 Immune-Checkpoint Inhibitors for Metastatic Colorectal Cancer: A Systematic Review of Clinical Outcomes ENSG00000138798 ENSG00000198793 ENSG00000112715 ENSG00000146648 PMC8647629__F1 The Renin–Angiotensin System in the Cancer Stem Cell Niche ENSG00000175054 ENSG00000168036 PMC2688381__F4 Azithromycin Treatment Alters Gene Expression in Inflammatory, Lipid Metabolism, and Cell Cycle Pathways in Well-Differentiated Human Airway Epithelia ENSG00000134824 PMC8500019__F3 Endothelial activation, dysfunction and immunothrombosis in COVID-19 ENSG00000003436 ENSG00000130234 PMC10942463__F10 Nucleotide metabolism associated with purine and pyrimidine pathways ENSG00000106348 ENSG00000124479 ENSG00000167325 PMC5410568__F1 The Role of Unfolded Protein Response and Mitogen-Activated Protein Kinase Signaling in Neurodegenerative Diseases with Special Focus on Prion Diseases ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC4414306__F5 IGFs/PI3K/Akt signaling pathway analysis using Ingenuity Molecule Activity Predictor (MAP) ENSG00000002330 ENSG00000198793 ENSG00000220205 PMC12106402__F1 Metabolite 2-aminoadipic acid: implications for metabolic disorders and therapeutic opportunities ENSG00000157426 ENSG00000105607 ENSG00000181192 PMC4414306__F4 Growth hormone signaling pathway analysis using Ingenuity Molecule Activity Predictor (MAP) ENSG00000245848 ENSG00000115415 ENSG00000169047 ENSG00000175899 ENSG00000168610 PMC4418918__F6 Translational effects of Stat1 ENSG00000115415 PMC3402097__F4 Lineage-specific and ubiquitous biological roles of the mammalian transcription factor LSF ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC8332857__F5 ZNF217: the cerberus who fails to guard the gateway to lethal malignancy ENSG00000157554 ENSG00000002330 ENSG00000065361 ENSG00000171940 PMC2667897__F1 TGFB superfamily signaling: notes from the desert ENSG00000157933 ENSG00000291971 ENSG00000198742 ENSG00000138798 ENSG00000126883 PMC10647460__F7 Regulatory mechanism of cis-9, trans-11 CLA on milk fat synthesis ENSG00000057663 ENSG00000132170 PMC8611103__F3 Disease-specific interactome alterations via epichaperomics: the case for Alzheimer’s disease ENSG00000163914 PMC7952440__F1 miRNAs flowing up and down to facilitate keratinocyte hyperproliferation ENSG00000100234 ENSG00000036672 ENSG00000125538 PMC3836193__F1 Role of apoptosis in colon cancer biology, therapy, and prevention ENSG00000026103 PMC5755720__F1 ERBB signaling in CTCs of ovarian cancer and glioblastoma ENSG00000065361 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000136997 ENSG00000168610 ENSG00000178568 PMC12056003__F7 IFITMs on CHIKV infection in human dermal cells ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000276561 PMC4586487__F6 PTBP1 and PTBP2 impaired autoregulation of SRSF3 in cancer cells ENSG00000011304 PMC7226765__F9 Overexpression of GRP78/BiP in P-Glycoprotein-Positive L1210 Cells is Responsible for Altered Response of Cells to Tunicamycin as a Stressor of the Endoplasmic Reticulum ENSG00000128272 ENSG00000100219 PMC5409837__F8 High-Throughput Screening of Tyrosine Kinase Inhibitor Cardiotoxicity with Human Induced Pluripotent Stem Cells ENSG00000171105 ENSG00000134853 PMC4177985__F1 LD-Aminopterin in the Canine Homologue of Human Atopic Dermatitis: A Randomized, Controlled Trial Reveals Dosing Factors Affecting Optimal Therapy ENSG00000228716 PMC8455910__F10 Gardenoside Hinders Caspase-1-Mediated Hepatocyte Pyroptosis Through the CTCF/DPP4 Signaling Pathway ENSG00000162711 ENSG00000197635 ENSG00000102974 PMC3075605__F2 NFKB signaling pathways downstream of TNFR1, TLR4 and TCR/CD28 ENSG00000102871 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000083799 ENSG00000175104 ENSG00000127191 ENSG00000143258 ENSG00000184216 PMC12056003__F4 Genes modulated by the expression of IFITM1, 2, and 3 in HFF-1 cells ENSG00000188379 ENSG00000213928 ENSG00000187796 ENSG00000102871 ENSG00000185436 ENSG00000157601 ENSG00000149294 ENSG00000169032 ENSG00000135341 ENSG00000142166 ENSG00000183735 ENSG00000239732 ENSG00000088888 ENSG00000198933 ENSG00000215301 ENSG00000164342 ENSG00000115267 ENSG00000276561 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000121060 ENSG00000184216 PMC4128340__F3 Canonical non-Smad pathway tumor growth factor (TGF)B signaling ENSG00000166340 ENSG00000162493 ENSG00000117298 ENSG00000178726 ENSG00000127472 ENSG00000245848 ENSG00000041982 ENSG00000159216 ENSG00000011422 ENSG00000145623 ENSG00000157227 ENSG00000196639 ENSG00000128342 ENSG00000051128 ENSG00000118257 ENSG00000140464 ENSG00000115107 ENSG00000024422 ENSG00000125266 ENSG00000124102 ENSG00000142227 ENSG00000070882 ENSG00000181523 ENSG00000134871 ENSG00000110628 ENSG00000168610 ENSG00000152684 ENSG00000185201 ENSG00000072110 ENSG00000135424 ENSG00000074410 ENSG00000134531 PMC7306774__F7 Proposed mechanism for CRY’s effect on susceptibility to stress-induced depression-like behavior ENSG00000132326 PMC4414306__F7 NRF2-mediated oxidative stress response ENSG00000166794 ENSG00000112964 ENSG00000178573 ENSG00000198838 ENSG00000188729 ENSG00000163064 ENSG00000135069 ENSG00000171033 ENSG00000052802 ENSG00000138356 ENSG00000079999 PMC7161485__F1 ADE and antibody mediated immunopathology. Left panel: For ADE, immune complex internalization is mediated by the engagement of activating Fc receptors on the cell surface ENSG00000115415 ENSG00000236625 PMC5932566__F2 Molecular and signaling impact of MUC5AC in various malignancies ENSG00000291363 ENSG00000137673 ENSG00000149968 ENSG00000170558 ENSG00000168036 ENSG00000169429 ENSG00000112715 PMC7122041__F9 Coagulation profile of endothelial surface during normal (left panel) and activated state (right panel) ENSG00000003436 ENSG00000134982 ENSG00000173599 ENSG00000122194 PMC4422082__F4 CD44- and CD44v-induced RTK for apoptosis resistance ENSG00000019991 ENSG00000291971 ENSG00000105401 ENSG00000160293 PMC7426366__F3 Action of ceramide on insulin signaling and glucose metabolism in muscle cells ENSG00000223802 ENSG00000105550 ENSG00000169047 PMC10382901__F5 Genetic alterations in MED12 promote castration-resistant prostate cancer through modulation of GLI3 signaling ENSG00000106571 ENSG00000127948 ENSG00000115419 PMC10912719__F2 DNPNB pathway ENSG00000128050 ENSG00000185129 ENSG00000146676 PMC9001080__F3 Targeting Nrf2-Mediated Oxidative Stress Response in Traumatic Brain Injury: Therapeutic Perspectives of Phytochemicals ENSG00000100387 ENSG00000079999 PMC8523568__F3 Extracellular calcium alters calcium-sensing receptor network integrating intracellular calcium-signaling and related key pathway ENSG00000136731 ENSG00000103266 ENSG00000156026 ENSG00000127022 ENSG00000036828 ENSG00000099246 ENSG00000108774 ENSG00000101558 ENSG00000089597 ENSG00000141367 ENSG00000143183 PMC3923981__F7 Cytosolic Functions of MORC2 in Lipogenesis and Adipogenesis ENSG00000131473 ENSG00000133422 ENSG00000026103 PMC7426366__F1 Metabolism of sphingolipids ENSG00000100422 ENSG00000119537 ENSG00000102172 PMC10912719__F7 Regulation of DNPNB enzyme clustering and purinosome assembly-disassembly under the control of regulatory proteins and signaling pathways ENSG00000128050 PMC3989821__F2 Prostate smooth muscle contraction and assumed connections to the regulation of prostate growth ENSG00000163914 PMC11016731__F3 Rationale for immune checkpoint inhibitors plus targeted therapy for advanced renal cell carcinoma ENSG00000178860 ENSG00000134086 ENSG00000291603 ENSG00000134982 ENSG00000198793 PMC11016731__F2 Mechanism of tumor cell genesis induced by hypoxia inducible factor (HIF) ENSG00000134086 ENSG00000198793 PMC6513836__F7 Brief summary of the possible mechanisms of KSHV-mediated pathogenesis at the cellular level ENSG00000170365 ENSG00000150782 ENSG00000148400 ENSG00000105810 ENSG00000114315 ENSG00000026103 PMC4023701__F5 Crosstalk pathway ENSG00000169071 ENSG00000145147 ENSG00000187608 ENSG00000184347 ENSG00000110651 ENSG00000120885 ENSG00000163737 ENSG00000112715 ENSG00000213949 ENSG00000041982 ENSG00000196549 ENSG00000128342 ENSG00000108821 ENSG00000169174 ENSG00000100448 ENSG00000162512 ENSG00000169439 ENSG00000189056 ENSG00000113140 ENSG00000000971 ENSG00000122786 ENSG00000007908 ENSG00000103742 ENSG00000108691 ENSG00000118785 ENSG00000160867 ENSG00000140285 ENSG00000144837 PMC9476726__F11 Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer ENSG00000128917 ENSG00000090932 PMC3241422__F8 Mpk1-driven FKS2 transcription ENSG00000149489 PMC9476726__F10 Regulatory effect of traditional Chinese medicines on signaling pathways of process from chronic atrophic gastritis to gastric cancer ENSG00000226275 ENSG00000170458 ENSG00000172936 ENSG00000175104 PMC4534763__F6 Identifying miRNA/mRNA negative regulation pairs in colorectal cancer ENSG00000145604 ENSG00000094804 ENSG00000132646 ENSG00000135336 ENSG00000123374 ENSG00000164754 ENSG00000205250 ENSG00000277273 ENSG00000166851 PMC5915111__F10 Signaling pathways in the glaucomatous trabecular meshwork ENSG00000170365 ENSG00000095739 ENSG00000136869 PMC4534763__F4 Identifying miRNA/mRNA negative regulation pairs in colorectal cancer ENSG00000169291 ENSG00000002330 ENSG00000110395 ENSG00000113070 ENSG00000198793 ENSG00000177606 ENSG00000158458 ENSG00000169752 PMC6163961__F4 Apoptosis inhibition in cancer ENSG00000002330 PMC3856408__F1 Endogenous small RNA pathways involved in host defense and viral pathogenesis in plants and animals ENSG00000092847 ENSG00000128191 ENSG00000113360 ENSG00000134698 ENSG00000123908 PMC6163961__F1 Apoptosis extrinsic and intrinsic (mitochondrial) pathways ENSG00000002330 ENSG00000138777 ENSG00000168040 ENSG00000084774 ENSG00000026103 PMC6163961__F2 Apoptosis intrinsic (endoplasmic reticulum (ER)) pathway ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC4613518__F1 Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention ENSG00000178573 ENSG00000100387 ENSG00000023909 ENSG00000187134 ENSG00000079999 PMC6389897__F2 Folate metabolism is linked to the homocysteine metabolic pathway ENSG00000205221 PMC5138253__F5 Different roles of Gq- and Gs-coupled GPCRs expressed by AgRP neurons in food intake ENSG00000063180 PMC12009754__F8 Graphical abstract of the study ENSG00000134982 ENSG00000168036 PMC8767067__F4 Aberrant Expression of miR-1301 in Human Cancer ENSG00000130939 ENSG00000087245 ENSG00000170558 ENSG00000168036 ENSG00000104332 ENSG00000112715 ENSG00000100664 ENSG00000168610 ENSG00000136826 ENSG00000057663 ENSG00000159216 ENSG00000132646 ENSG00000026508 ENSG00000123374 ENSG00000168646 PMC2728081__F2 Regulation of B-cell entry into the cell cycle ENSG00000124102 ENSG00000186716 PMC6224214__F8 Liver X Receptor (LXR) pathway as the result of the integration between transcriptomic and metabolomic data ENSG00000110244 ENSG00000113161 PMC2981059__F6 HER/HER2-PI3K-Akt-NFKB-elicited pathway in prostate cancer cells ENSG00000138798 ENSG00000173039 PMC8948514__F1 Case series of cerebral venous thrombosis as the first manifestation of homocystinuria PMC8626127__F8 Ovalbumin antigen-specific activation of human T cell receptor closely resembles soluble antibody stimulation as revealed by BOOST phosphotyrosine proteomics ENSG00000291603 ENSG00000213658 ENSG00000081237 ENSG00000198851 ENSG00000188130 ENSG00000113263 ENSG00000124181 PMC6838365__F40 Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3B/Beta-catenin signaling pathway ENSG00000100345 ENSG00000168036 ENSG00000065559 ENSG00000175104 PMC11906485__F1 Biosynthetic pathway of plasmalogens and RCDP types based on gene mutation ENSG00000018510 ENSG00000288217 ENSG00000197601 PMC6111868__F7 Signalling pathway by which kallistatin inhibits endothelial senescence, oxidative stress and inflammation ENSG00000162692 ENSG00000096717 PMC6105545__F6 Persistent EcoHIV infection induces nigral degeneration ENSG00000108691 ENSG00000145839 ENSG00000111537 ENSG00000109320 ENSG00000291971 ENSG00000136869 ENSG00000126353 ENSG00000113525 PMC7811275__F3 Regulation of the ZBP1-NLRP3 inflammasome and its implications in pyroptosis, apoptosis, and necroptosis (PANoptosis) ENSG00000278718 ENSG00000162711 ENSG00000124256 ENSG00000213928 ENSG00000137275 ENSG00000138794 ENSG00000168040 ENSG00000125347 ENSG00000164305 ENSG00000142166 ENSG00000088888 ENSG00000168404 ENSG00000064012 ENSG00000285379 PMC2782690__F3 Is cancer a disease of abnormal cellular metabolism? ENSG00000180210 ENSG00000122966 ENSG00000136997 ENSG00000078237 PMC5938286__F2 PD-1/PD-Ls signaling pathway ENSG00000291603 ENSG00000134982 ENSG00000198793 PMC5940272__F1 Alternative pathways of type I IFN induction during M ENSG00000183735 ENSG00000164430 ENSG00000167207 ENSG00000136869 PMC5938286__F1 Illustration of cross-communication network of BCR, PI3K, apoptosis, and NFKB signaling pathways ENSG00000104856 ENSG00000102871 ENSG00000186716 ENSG00000198793 ENSG00000136997 ENSG00000173039 ENSG00000158825 ENSG00000172936 ENSG00000171791 ENSG00000168040 ENSG00000010671 ENSG00000198286 PMC3256223__F1 Modeling of miRNA and Drug Action in the EGFR Signaling Pathway ENSG00000002330 ENSG00000138798 ENSG00000146648 PMC4389797__F7 Schematic showing the TGFB/LIF- mediated tumor suppressive role in melanoma ENSG00000128342 ENSG00000168610 PMC5938286__F3 Illustration of JAK/STAT signaling pathway ENSG00000291971 ENSG00000198793 ENSG00000136997 ENSG00000171791 PMC3742001__F7 Schematic diagram summarizing the signaling pathways relevant to this study PMC8928136__F4 Signaling pathways by DJ-1: An updated overview ENSG00000175104 ENSG00000127191 PMC8928136__F3 Signaling pathways by DJ-1: An updated overview ENSG00000214253 PMC8928136__F5 Signaling pathways by DJ-1: An updated overview ENSG00000138794 ENSG00000096717 PMC5515553__F1 Crosstalk between STAT5 activation and PI3K/AKT functions in normal and transformed mammary epithelial cells ENSG00000128342 ENSG00000168610 ENSG00000113494 PMC8928136__F2 Signaling pathways by DJ-1: An updated overview ENSG00000104081 PMC6514318__F1 Molecular genetic pathways in long-term epilepsy-associated tumors (LEATs) and pediatric type diffuse low-grade glioma (DLGG) ENSG00000177169 ENSG00000123395 ENSG00000157764 ENSG00000169047 ENSG00000118515 ENSG00000155792 ENSG00000077782 ENSG00000196712 PMC3700727__F1 The Aryl Hydrocarbon Receptor: A Novel Target for Immunomodulation in Organ Transplantation ENSG00000140465 ENSG00000106546 PMC7494983__F5 Epigenetic modification and therapeutic targets of diabetes mellitus ENSG00000169047 PMC5760518__F5 Signaling pathway activated by piperonylic acid ENSG00000168610 ENSG00000146648 PMC8884172__F10 Downregulation of Three Immune-Specific Core Genes and the Regulatory Pathways in Children and Adult Friedreich's Ataxia: A Comprehensive Analysis Based on Microarray ENSG00000026103 PMC9262990__F14 Anti-neoplastic action of Cimetidine/Vitamin C on histamine and the PI3K/AKT/mTOR pathway in Ehrlich breast cancer ENSG00000169047 ENSG00000198793 ENSG00000015285 PMC7594527__F1 Lipid metabolic pathway in S ENSG00000090402 ENSG00000173599 ENSG00000198670 PMC9168369__F1 Novel 1,2,3-Triazole Erlotinib Derivatives as Potent IDO1 Inhibitors: Design, Drug-Target Interactions Prediction, Synthesis, Biological Evaluation, Molecular Docking and ADME Properties Studies ENSG00000188676 PMC3489783__F3 Representative KEGG pathway change of Endocytosis ENSG00000180210 ENSG00000131475 ENSG00000115561 ENSG00000151657 ENSG00000130164 ENSG00000136100 ENSG00000165527 ENSG00000146648 ENSG00000024422 PMC12150572__F8 Role of CIP2A in OA cartilage ENSG00000162924 ENSG00000103888 ENSG00000174611 ENSG00000163507 PMC3766957__F2 Cancer metabolism: fatty acid oxidation in the limelight ENSG00000065833 ENSG00000173599 ENSG00000169710 ENSG00000175567 PMC8156589__F1 Diabetic Retinopathy and NADPH Oxidase-2: A Sweet Slippery Road PMC8532171__F6 Flg22- and D-glucose-biased signaling ENSG00000105205 PMC6480114__F1 Proposed mechanical cues regulates Hippo signaling pathway in gastric tumorigenesis ENSG00000126016 ENSG00000137727 ENSG00000291971 ENSG00000163914 ENSG00000136997 ENSG00000145321 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC2647614__F2 Novel Insights into Lung Transplant Rejection by Microarray Analysis ENSG00000100385 ENSG00000134460 ENSG00000113520 ENSG00000113525 ENSG00000137801 PMC9489610__F5 Necroptotic signaling mechanisms and outcomes in ALS ENSG00000183735 ENSG00000123240 ENSG00000137275 ENSG00000168040 ENSG00000168404 ENSG00000064012 ENSG00000285379 PMC3576254__F5 Pathway analysis ENSG00000084093 ENSG00000134982 ENSG00000111837 ENSG00000173599 ENSG00000177606 ENSG00000196712 ENSG00000026103 PMC8064146__F5 Transcriptome and lipidome profile of human mesenchymal stem cells with reduced senescence and increased trilineage differentiation ability upon drug treatment ENSG00000163624 ENSG00000198964 ENSG00000182156 ENSG00000173599 ENSG00000111684 ENSG00000099194 ENSG00000241878 PMC9489610__F3 Evidence for activation of apoptosis in ALS ENSG00000132906 ENSG00000183735 ENSG00000002330 ENSG00000137275 ENSG00000171791 ENSG00000164305 ENSG00000147894 PMC186326__F7 Model for Fgf18 regulation of long bone growth ENSG00000066468 ENSG00000156427 ENSG00000128602 ENSG00000077782 ENSG00000163501 PMC7139751__F1 Akt signaling pathway ENSG00000124102 ENSG00000002330 ENSG00000198793 ENSG00000145979 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC10384200__F4 Association between High Interferon-Gamma Production in Avian Tuberculin-Stimulated Blood from Mycobacterium avium subsp. paratuberculosis-Infected Cattle and Candidate Genes Implicated in Necroptosis ENSG00000188486 ENSG00000099985 ENSG00000137033 ENSG00000168040 ENSG00000182511 ENSG00000189403 ENSG00000131323 ENSG00000083799 ENSG00000100504 ENSG00000168404 ENSG00000285379 ENSG00000143258 ENSG00000127948 PMC3208682__F1 Expression patterns of the TLR signaling pathway in CLL ENSG00000243414 ENSG00000104365 ENSG00000100906 ENSG00000109320 ENSG00000095015 ENSG00000173039 ENSG00000065559 ENSG00000185187 ENSG00000213341 ENSG00000130159 ENSG00000150455 ENSG00000135341 ENSG00000127666 ENSG00000168811 ENSG00000010671 ENSG00000183735 ENSG00000111537 ENSG00000170458 ENSG00000177606 ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC3094730__F2 Dendritic cell control of tolerogenic responses ENSG00000049768 PMC6676383__F5 Metabolic pathway map showing fold changes of leaf metabolite concentrations of Plantago lanceolata subjected to different precipitation and temperature treatments ENSG00000122966 ENSG00000172005 PMC8862784__F2 ACE2: a key modulator of the renin-angiotensin system and pregnancy ENSG00000181019 ENSG00000130234 ENSG00000125538 PMC7104985__F2 Broad depiction of the endoplasmic reticulum (ER) stress-driven unfolded protein response (UPR) signaling ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC7104985__F1 Schematic depiction of production and sensing mechanisms for type I interferons (IFNs) ENSG00000198793 ENSG00000169047 ENSG00000168610 ENSG00000276561 ENSG00000183735 ENSG00000138378 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000136869 ENSG00000164342 PMC6125320__F7 The molecular mechanisms underlying the role of mTOR/p70S6K/HIF-1A signaling pathway in the regulation of TLR4 inflammatory signaling and TH17 cells in liver IRI ENSG00000136869 ENSG00000162772 ENSG00000175104 PMC11003953__F3 Relationship Between Short-chain Fatty Acids and Parkinson’s Disease: A Review from Pathology to Clinic PMC11003953__F2 Relationship Between Short-chain Fatty Acids and Parkinson’s Disease: A Review from Pathology to Clinic ENSG00000105329 ENSG00000131096 PMC9699542__F4 Mitophagy Induced by Metal Nanoparticles for Cancer Treatment ENSG00000198793 ENSG00000158828 PMC3836169__F1 PTEN in cancer, metabolism and aging ENSG00000117525 ENSG00000150907 ENSG00000169047 ENSG00000167965 PMC83901__F8 Model of the regulation of class II MHC genes by IFNG ENSG00000111537 ENSG00000115415 PMC9146539__F1 Expression Analysis of Genes Involved in Transport Processes in Mice with MPTP-Induced Model of Parkinson’s Disease ENSG00000182718 ENSG00000144566 ENSG00000149295 PMC10893548__F7 NMN promotes hair growth by regulating the paracrine system of cells ENSG00000125538 ENSG00000168036 PMC9489610__F1 Immunological outcomes of apoptosis versus programmed necrotic mechanisms ENSG00000153208 ENSG00000158156 ENSG00000101974 PMC2013861__F4 Signalling pathways activated by the RXFPs ENSG00000133105 ENSG00000173080 ENSG00000291971 ENSG00000277069 ENSG00000146648 PMC4889216__F7 Mitochondrial stress induces chromatin reorganization to promote longevity and UPRmt ENSG00000151376 ENSG00000065833 ENSG00000082212 PMC6843654__F4 Top three molecular networks identified by Ingenuity Pathway Analysis (IPA): (a) Network 1 ENSG00000121578 ENSG00000155827 ENSG00000154358 ENSG00000138622 ENSG00000113140 ENSG00000135476 ENSG00000099942 ENSG00000166068 ENSG00000101680 ENSG00000114857 ENSG00000184500 ENSG00000183765 ENSG00000103811 ENSG00000170365 ENSG00000107290 ENSG00000186575 ENSG00000197860 ENSG00000166391 ENSG00000163131 ENSG00000083782 ENSG00000138162 ENSG00000154654 ENSG00000115808 ENSG00000155657 PMC7983894__F4 Oxidative stress leads to multiple death modalities through various pathways in melanocyte ENSG00000143799 ENSG00000278718 ENSG00000162711 ENSG00000137275 ENSG00000156709 ENSG00000189403 ENSG00000168404 ENSG00000142082 ENSG00000285379 ENSG00000079999 PMC7568049__F1 SARS-CoV-2 infection pathway in humans and COVID-19 progression ENSG00000042832 ENSG00000130234 ENSG00000173599 PMC5344271__F3 Upon SV40 infection of mesothelial cells, Tag (Large T) and tag (small t) antigens are expressed ENSG00000019991 ENSG00000148400 ENSG00000146648 ENSG00000140443 PMC6668073__F4 Hedgehog signalling and SMO inhibitors action in MB ENSG00000106571 ENSG00000117425 ENSG00000128602 PMC6327307__F3 Epigenetic control of CD8+ T cell differentiation ENSG00000141867 ENSG00000198901 ENSG00000139187 ENSG00000156127 ENSG00000150907 ENSG00000133961 ENSG00000096717 ENSG00000109670 PMC6327307__F2 Epigenetic control of CD8+ T cell differentiation ENSG00000088305 ENSG00000145321 PMC6222347__F7 Suggested mechanism of action of morusin in MDI-stimulated 3T3-L1 cells and primary adipocytes ENSG00000245848 ENSG00000026103 PMC3800035__F7 Heterotrimeric G-Protein, GA16, Is a Critical Downstream Effector of Non-Canonical Wnt Signaling and a Potent Inhibitor of Transformed Cell Growth in Non Small Cell Lung Cancer ENSG00000154342 ENSG00000154764 ENSG00000281324 ENSG00000169071 ENSG00000185483 ENSG00000168036 PMC6434253__F2 Sub-pathways identified using the sub-pathway strategy ENSG00000117020 ENSG00000197951 ENSG00000065361 ENSG00000065029 ENSG00000198793 ENSG00000177606 ENSG00000136997 ENSG00000149782 ENSG00000119596 ENSG00000213341 ENSG00000146648 ENSG00000160691 PMC4839264__F7 mTOR signaling in ALK+ ALCL oncogenesis ENSG00000198793 ENSG00000164327 PMC3070842__F1 Lessons on transcriptional control from the serum response network ENSG00000111537 PMC2860379__F2 Genes affecting dystroglycan glycosylation associated with congenital muscular dystrophy ENSG00000009830 ENSG00000130714 ENSG00000181027 PMC2684977__F2 Biologic actions of isoprenoids PMC4496162__F3 MicroRNAs in apoptosis, autophagy and necroptosis ENSG00000002330 ENSG00000144895 ENSG00000198793 ENSG00000167965 ENSG00000145782 PMC5388243__F7 Schematic of the proposed mechanism of MIR506 induction of autophagy-related cell death in PDAC cells through the STAT3 signaling pathway ENSG00000171791 ENSG00000168610 PMC8478810__F2 Wnt pathway: an important control mechanism in bone’s response to mechanical loading ENSG00000162337 ENSG00000134569 ENSG00000167941 PMC8478810__F4 Wnt pathway: an important control mechanism in bone’s response to mechanical loading ENSG00000169218 ENSG00000162337 ENSG00000133067 ENSG00000183579 ENSG00000108375 PMC4496162__F4 MicroRNAs in apoptosis, autophagy and necroptosis ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000247077 ENSG00000164342 PMC7968933__F2 Mechanisms through which biological sex could affect BBB integrity ENSG00000163914 ENSG00000185591 ENSG00000162692 ENSG00000121807 PMC5867300__F1 Immune modulatory signaling in antigen-presenting cells (APCs) induced by binding of interleukin-10 (IL-10) to the IL-10 receptor ENSG00000291507 ENSG00000105397 ENSG00000125538 ENSG00000110324 ENSG00000168610 PMC5659283__F2 PTEN controls the G2-M transition to prevent bypass of the G2 checkpoints and premature entry into mitosis (M) ENSG00000175054 ENSG00000134057 ENSG00000131747 ENSG00000072609 PMC6938687__F2 The RTK-PI3K-AKT-mTOR signaling pathway ENSG00000124102 ENSG00000100150 ENSG00000117020 ENSG00000114388 ENSG00000145979 ENSG00000136997 ENSG00000155792 ENSG00000118971 ENSG00000140443 PMC6752985__F1 PI3-K/Akt signaling pathway ENSG00000123374 PMC7168269__F1 Roles of gastric cancer stem cells (GCSCs) in the immune microenvironment ENSG00000107562 ENSG00000168610 PMC4127596__F2 Beclin 1, its protein interactions and its role in autophagy ENSG00000110497 ENSG00000198382 ENSG00000158828 ENSG00000189403 ENSG00000175104 ENSG00000062716 PMC4127596__F1 Autophagic process and some of its major regulators ENSG00000177169 ENSG00000169047 ENSG00000145782 ENSG00000057663 PMC10302309__F2 Resistance to EGFR-TKIs in Non-Small Cell Lung Cancer: From Molecular Mechanisms to Clinical Application of New Therapeutic Strategies ENSG00000157764 ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000047936 ENSG00000118971 ENSG00000146648 ENSG00000139687 PMC3742652__F4 Proposed Twist2 involvment in ovarian cancer ENSG00000002330 ENSG00000288335 ENSG00000171791 PMC7643212__F4 Tumor necrosis factor receptor-associated factor 1 pathways involved in T cell survival ENSG00000150907 ENSG00000056558 ENSG00000105639 PMC8074086__F1 Mycosis Fungoides and Sézary Syndrome: An Integrative Review of the Pathophysiology, Molecular Drivers, and Targeted Therapy ENSG00000138378 ENSG00000115415 ENSG00000137077 ENSG00000173757 ENSG00000107485 ENSG00000126353 ENSG00000049768 ENSG00000124181 ENSG00000105639 ENSG00000168610 ENSG00000198286 PMC8274420__F4 Novel Prognostic Biomarkers in Metastatic and Locally Advanced Colorectal Cancer: Micronuclei Frequency and Telomerase Activity in Peripheral Blood Lymphocytes ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000164362 ENSG00000168036 ENSG00000146648 PMC3884931__F1 Mammalian target of rapamycin (mTOR) signaling pathway regulation ENSG00000138798 PMC2755790__F1 Network analysis of differentially expressed proteins (red symbols) involved in arteriogenesis ENSG00000125266 ENSG00000177606 ENSG00000174429 ENSG00000007171 PMC8478810__F1 Wnt pathway: an important control mechanism in bone’s response to mechanical loading ENSG00000162337 ENSG00000134982 PMC5309878__F3 Serum lipid alterations identified in chronic hepatitis B, hepatitis B virus-associated cirrhosis and carcinoma patients ENSG00000087253 ENSG00000125538 ENSG00000173599 ENSG00000291994 ENSG00000111684 ENSG00000198670 ENSG00000153395 ENSG00000133027 PMC9304626__F1 Oxidative Stress and Lipid Peroxidation: Prospective Associations Between Ferroptosis and Delayed Wound Healing in Diabetic Ulcers ENSG00000151012 ENSG00000167468 PMC5006924__F7 IL-10-producing B cells induced by TRAPs ENSG00000172936 PMC8138659__F2 Nkx3.1 in Cancers and Stemness ENSG00000168610 ENSG00000136826 PMC9181656__F2 Notch Signaling in Breast Tumor Microenvironment as Mediator of Drug Resistance ENSG00000108691 ENSG00000148400 ENSG00000121807 ENSG00000168610 PMC4142215__F1 Genome wide proteomics of ERBB2 and EGFR and other oncogenic pathways in inflammatory breast cancer ENSG00000169291 ENSG00000002330 ENSG00000110395 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000178568 PMC5581331__F2 P53 and pRB pathways during senescence ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC11956214__F8 Cell cycle signaling and key proteins ENSG00000065833 ENSG00000179091 ENSG00000132646 ENSG00000172005 ENSG00000123374 PMC8301816__F2 Epithelial Protein Lost in Neoplasm, EPLIN, the Cellular and Molecular Prospects in Cancers ENSG00000291971 ENSG00000138798 ENSG00000168036 ENSG00000168610 ENSG00000146648 ENSG00000140443 PMC12153268__F7 The mechanism of LAG3 inhibition of IFNG production by NK cells ENSG00000089692 ENSG00000111537 ENSG00000115415 ENSG00000198793 ENSG00000136997 ENSG00000135069 ENSG00000159399 PMC5662495__F2 Mitochondrial Ribosomes in Cancer ENSG00000168040 PMC8601163__F1 Auxin‐mediated induction of GAL promoters by conditional degradation of Mig1p improves sesquiterpene production in Saccharomyces cerevisiae with engineered acetyl‐CoA synthesis ENSG00000069482 ENSG00000197429 PMC3576161__F1 Folate metabolic pathway ENSG00000086205 ENSG00000124275 ENSG00000116984 PMC4774966__F5 Tolerant and Susceptible Sesame Genotypes Reveal Waterlogging Stress Response Patterns ENSG00000122882 ENSG00000268041 ENSG00000168938 ENSG00000164778 PMC3022058__F1 Outline of UDP-GlcNAc synthetic pathways ENSG00000159921 ENSG00000147162 PMC1083933__F2 Cell cycle trials in Salamanca ENSG00000172680 ENSG00000134057 ENSG00000276876 PMC2293256__F4 Reannotation processes ENSG00000053438 ENSG00000099810 ENSG00000008130 PMC3888285__F2 Liver responds to iron signals to regulate hepcidin production ENSG00000170365 ENSG00000010704 ENSG00000106327 ENSG00000125968 PMC5876067__F2 Inhibition of the BRCA1 DNA damage response pathway indicated by a down modulation (green; up-modulation is indicated in red) of atm, brip1, cdkn1a, e2f3, fancd2, fancl, mdc1, rad51, and rpa1 in male X ENSG00000149311 ENSG00000169291 ENSG00000123268 PMC5131788__F2 Molecular mechanisms underlying alcohol-drinking behaviours ENSG00000132326 ENSG00000179094 ENSG00000101327 ENSG00000196712 PMC5540801__F4 Shh pathway targets and regulatory networks ENSG00000052850 ENSG00000157557 ENSG00000164161 ENSG00000144857 ENSG00000244405 ENSG00000101115 ENSG00000175832 ENSG00000164107 ENSG00000135111 ENSG00000164690 ENSG00000128602 PMC7816003__F1 Heat shock protein 22 modulates NRF1/TFAM-dependent mitochondrial biogenesis and DRP1-sparked mitochondrial apoptosis through AMPK-PGC1A signaling pathway to alleviate the early brain injury of subarachnoid hemorrhage in rats ENSG00000175567 ENSG00000106459 PMC8968515__F9 Loss of LAT1 sex-dependently delays recovery after caerulein-induced acute pancreatitis ENSG00000148926 ENSG00000198793 PMC5876695__F6 Meta-network illustrating synergistic interventions and resistance mechanisms to PI3K inhibitors ENSG00000002330 ENSG00000136997 ENSG00000118515 ENSG00000129514 ENSG00000123374 ENSG00000171791 PMC7268490__F1 Schematic diagram of experimental workflow ENSG00000143839 ENSG00000104368 PMC5876695__F3 Network model of oncogenic signal transduction in ER+ breast cancer ENSG00000002330 ENSG00000135446 ENSG00000136997 ENSG00000118515 ENSG00000129514 ENSG00000123374 ENSG00000105810 ENSG00000171791 PMC9358906__F6 Type I interferon signature by VGLL3 in the fibroblast-like synoviocytes of rheumatoid arthritis patients via targeting the Hippo pathway ENSG00000105397 ENSG00000115415 ENSG00000018408 ENSG00000114019 ENSG00000142166 PMC11208122__F12 Scutellarin alleviates microglia‐mediated neuroinflammation and apoptosis after ischemic stroke through the PI3K/AKT/GSK3B signaling pathway ENSG00000177455 PMC8767413__F4 Assessing the Potential Value and Mechanism of Kaji-Ichigoside F1 on Arsenite-Induced Skin Cell Senescence ENSG00000172216 ENSG00000138798 PMC4508501__F3 Altered steps in miRNA biogenesis lead to cancer ENSG00000139546 ENSG00000100697 ENSG00000124571 ENSG00000113360 PMC7795003__F2 IGF-1 receptor, insulin receptor and hybrid receptor ENSG00000198793 ENSG00000140443 PMC4508501__F1 miRNA biogenesis process ENSG00000124571 ENSG00000113360 ENSG00000123908 PMC7795003__F1 Growth hormone (GH) receptor PMC7795003__F3 Interplay of GH, IGF-1, insulin, hybrid receptor and nutrients in the muscle ENSG00000177058 ENSG00000198793 PMC8105775__F2 Caveolin-1 in the biofate and efficacy of anti-tumor drugs and their nano-drug delivery systems ENSG00000214285 PMC8852737__F4 Synthesis and Antitumor Evaluation of Menthone-Derived Pyrimidine-Urea Compounds as Potential PI3K/Akt/mTOR Signaling Pathway Inhibitor ENSG00000143799 ENSG00000157404 ENSG00000044115 ENSG00000291971 ENSG00000087586 ENSG00000169032 ENSG00000145386 ENSG00000164305 ENSG00000179295 ENSG00000163631 ENSG00000082175 ENSG00000188257 ENSG00000128052 ENSG00000123374 ENSG00000113263 ENSG00000077782 ENSG00000087245 ENSG00000171105 ENSG00000109743 ENSG00000105639 ENSG00000124588 ENSG00000132170 ENSG00000066468 ENSG00000100985 ENSG00000149554 ENSG00000146648 ENSG00000178568 PMC5840040__F3 Thermodynamic description of the eIF2B catalytic cycle ENSG00000159224 ENSG00000120690 PMC7753017__F4 Four pillars of sarcoidosis model ENSG00000149311 ENSG00000170458 ENSG00000198793 PMC8511144__F7 Phenylephrine increases tear Cathepsin S secretion in healthy murine lacrimal gland acinar cells through an alternative secretory pathway ENSG00000041353 ENSG00000005893 PMC6981390__F2 The biosynthetic pathways (terpenoids, bitter acid, phenylpropanoids and flavonoid) in the hop ENSG00000060982 ENSG00000197429 PMC11006979__F2 Unveiling the impact of CDK8 on tumor progression: mechanisms and therapeutic strategies ENSG00000136807 ENSG00000115415 ENSG00000132964 PMC7179464__F1 Macrophage migration inhibitory factor (MIF) and cancer pathway ENSG00000019582 ENSG00000002330 ENSG00000026508 ENSG00000121966 PMC8147889__F3 Mechanisms of HBV-Induced Hepatocellular Carcinoma ENSG00000033327 ENSG00000281324 ENSG00000162337 ENSG00000178573 ENSG00000134982 ENSG00000150907 ENSG00000169047 ENSG00000168036 ENSG00000168610 ENSG00000079999 PMC9508091__F2 Interplays of glucose metabolism and KRAS mutation in pancreatic ductal adenocarcinoma ENSG00000100522 ENSG00000147162 PMC9508091__F1 Mutant KRAS mediated metabolic alterations ENSG00000065833 ENSG00000115419 PMC8196151__F3 Phosphoproteome analysis with equal loading TMT11 provides a comprehensive overview of cancer-relevant pathways ENSG00000132906 ENSG00000002330 ENSG00000157764 ENSG00000116044 ENSG00000198793 ENSG00000134757 ENSG00000136352 ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000181019 ENSG00000186716 ENSG00000136997 ENSG00000146648 PMC9086968__F6 14,15-Epoxyeicosatrienoic Acid Protect Against Glucose Deprivation and Reperfusion-Induced Cerebral Microvascular Endothelial Cells Injury by Modulating Mitochondrial Autophagy via SIRT1/FOXO3a Signaling Pathway and TSPO Protein ENSG00000109819 ENSG00000101945 ENSG00000108179 ENSG00000150907 ENSG00000129152 ENSG00000096717 ENSG00000132170 PMC7666984__F1 TLR4 signaling pathway (schematic) ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000276561 PMC4456452__F17 Pathway model for fly-wasp mediated social learning ENSG00000102081 PMC9107748__F3A Transcriptome profiling and proteomic validation reveals targets of the androgen receptor signaling in the BT-474 breast cancer cell line ENSG00000136997 ENSG00000178568 PMC6232868__F1 Schematic representation correlating various factors such as light, eye, melanopsin, pineal gland, vitamin D, intestinal calcium, and gut microbiota to neuroinflammation and MS ENSG00000170458 ENSG00000136869 PMC2042178__F2 PTEN/PI3K/mTOR/STAT3 signaling involved in breast cancer stem-like cell survival and proliferation ENSG00000198793 ENSG00000168610 PMC5365005__F6 Sclareolide pathway enhances gemcitabine-induced gemcitabine-resistant human pancreatic cancer cell death ENSG00000122691 ENSG00000167325 PMC9047489__F1 Epithelial-Mesenchymal Transition-Inducing Factors Involved in the Progression of Lung Cancers ENSG00000176692 PMC8980082__F4 LncRNAs in the regulation of pyroptosis in NSCLC ENSG00000278718 ENSG00000162711 ENSG00000150782 ENSG00000173039 ENSG00000172936 ENSG00000136869 PMC8980082__F2 LncRNAs participate in the regulation of the apoptotic pathways in NSCLC ENSG00000002330 ENSG00000102871 ENSG00000171791 ENSG00000168040 PMC12024087__F9 Bta-Let-7d Modulation of Oxidative Stress Induced by Potassium Permanganate in Bovine Endometrial Cells via IGF1R/PI3K/AKT Signaling Pathway ENSG00000198793 ENSG00000171791 ENSG00000140443 PMC5295493__F2 Dietary triglycerides as signaling molecules that influence reward and motivation ENSG00000042832 ENSG00000170209 PMC3165056__F4 Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: Key regulators of innate immunity ENSG00000102871 ENSG00000131323 ENSG00000168040 ENSG00000175104 ENSG00000127191 ENSG00000276561 PMC8027411__F9 RAB31 marks and controls an ESCRT-independent exosome pathway ENSG00000168461 ENSG00000189375 ENSG00000135404 PMC3589543__F7 A pathway choice model for repair of a DNA DSB in Arabidopsis ENSG00000198887 PMC6160413__F6 Impact of osmotic stress on central carbon metabolism ENSG00000116001 ENSG00000122966 ENSG00000100412 ENSG00000146701 PMC5651906__F8 PTP4A1 promotes TGFB signaling in DFs ENSG00000184007 ENSG00000112245 ENSG00000291971 PMC7216742__F3 Fyn signaling pathway ENSG00000177169 ENSG00000126775 ENSG00000010810 ENSG00000168610 PMC4586096__F1 G2E3 attenuating replicative stress ENSG00000175054 ENSG00000132646 ENSG00000070950 PMC5070123__F3 Major pathways affected in cancer- and drug-induced cachexia ENSG00000104812 ENSG00000160789 ENSG00000151726 ENSG00000122218 ENSG00000143318 ENSG00000077522 ENSG00000178209 ENSG00000166147 ENSG00000117054 ENSG00000136842 ENSG00000068976 ENSG00000100504 ENSG00000024422 ENSG00000109061 ENSG00000143549 ENSG00000116748 ENSG00000285321 ENSG00000154358 ENSG00000100994 ENSG00000101306 ENSG00000197616 ENSG00000133055 ENSG00000140416 ENSG00000197079 ENSG00000135443 ENSG00000101605 ENSG00000205426 ENSG00000164591 ENSG00000161850 ENSG00000163157 ENSG00000072110 ENSG00000115361 ENSG00000122971 ENSG00000185129 ENSG00000105379 ENSG00000188783 PMC7492772__F3 NRX-based and LAR-RPTP-based synaptic organizing complexes display contrasting AB sensitivity ENSG00000142192 ENSG00000198739 ENSG00000281879 ENSG00000169760 PMC10571814__F8 Oxytocin signalling pathway, with yellow boxes representing proteins identified in this study and green circles representing metabolites identified in this study ENSG00000133083 ENSG00000168530 ENSG00000157764 ENSG00000198336 ENSG00000154358 ENSG00000291971 ENSG00000101470 ENSG00000284161 ENSG00000167658 ENSG00000116741 ENSG00000169032 ENSG00000081189 ENSG00000188089 ENSG00000159200 ENSG00000129757 ENSG00000243708 ENSG00000167535 ENSG00000180209 ENSG00000164068 ENSG00000160808 ENSG00000120729 ENSG00000138119 ENSG00000146648 ENSG00000196465 PMC8228963__F8 Foxtail Millet Improves Blood Glucose Metabolism in Diabetic Rats through PI3K/AKT and NFKB Signaling Pathways Mediated by Gut Microbiota ENSG00000125538 ENSG00000026103 PMC8834311__F5 Endocrine Fibroblast Growth Factors in Relation to Stress Signaling ENSG00000118972 ENSG00000105550 PMC8834311__F4 Endocrine Fibroblast Growth Factors in Relation to Stress Signaling ENSG00000118972 ENSG00000128272 ENSG00000144895 ENSG00000105550 PMC9124765__F2 Biomechanical Regulatory Factors and Therapeutic Targets in Keloid Fibrosis PMC8836129__F4 R-Loop-Associated Genomic Instability and Implication of WRN and WRNIP1 ENSG00000149311 ENSG00000124535 ENSG00000175054 ENSG00000051180 PMC7472464__F7 Overview of metabolic reprogramming in adipose tissue in EgPSC infected mice ENSG00000102794 ENSG00000062485 PMC6781720__F1 Schematic overview of the TLR4 signaling pathway ENSG00000170458 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC5190013__F10 Wnt-beta-catenin pathway signals metastasis-associated tumor cell phenotypes in triple negative breast cancers ENSG00000281324 ENSG00000137673 ENSG00000162337 ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC11769711__F2 Canonical Wnt signaling pathway and targeted therapy in AS ENSG00000281324 ENSG00000125398 ENSG00000162337 ENSG00000141448 ENSG00000134982 ENSG00000168036 PMC11769711__F1 Canonical and noncanoical TGF‐B signaling pathway and targeted therapy in AS (BMP signaling pathway is not shown) ENSG00000145147 ENSG00000105550 ENSG00000198793 ENSG00000283100 ENSG00000130513 PMC11895685__F1 Mechanisms and Therapeutic Implications of PI3K Signaling in Airway Inflammation and Remodeling in Asthma ENSG00000145839 ENSG00000137033 ENSG00000113520 ENSG00000145777 ENSG00000113525 PMC4169059__F2 AC in vascular endothelium ENSG00000181019 ENSG00000291971 ENSG00000162692 ENSG00000079999 PMC7045390__F6 Correlation analysis of the hypoxic transcriptome and metabolome data ENSG00000074800 ENSG00000254986 ENSG00000100412 ENSG00000146005 ENSG00000118520 ENSG00000169299 PMC11758636__F9 Lin28b-let-7 Modulates mRNA Expression of GnRH1 Through Multiple Signaling Pathways Related to Glycolysis in GT1-7 Cells ENSG00000198793 ENSG00000170498 ENSG00000187772 PMC11769711__F4 Mechanistic models of AS ENSG00000162711 ENSG00000133110 ENSG00000172936 PMC7862327__F3 PI3K–AKT–mTOR signaling cascade and other related pathways involved in FCD ENSG00000140992 ENSG00000100150 ENSG00000114388 ENSG00000171105 ENSG00000158748 ENSG00000169047 ENSG00000155792 PMC11769711__F3 NF‐KB signaling pathway and NLRP3 inflammasome in AS ENSG00000162711 ENSG00000141448 ENSG00000196591 ENSG00000173039 ENSG00000172936 ENSG00000175104 PMC5753034__F6 DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV‐1 infection of macrophages ENSG00000073111 PMC11592033__F1 Image depicts a signaling pathway where neurotransmitters bind to membrane receptors, activating G-proteins and effector proteins to produce second messengers like Ca2⁺ and cAMP ENSG00000125740 ENSG00000130522 PMC10145676__F1 Main metabolic pathways related to myo-inositol transformation inside the cell ENSG00000068745 ENSG00000176095 ENSG00000151151 PMC5572370__F7 Pathways of activation of naïve CD4+CD25+ T regulatory cell (Treg) (tTreg) ENSG00000134982 ENSG00000049768 PMC3889256__F7 Rsu1 is a critical component for regulation of p38 Map kinase signaling from the IPP complex ENSG00000070831 ENSG00000149269 ENSG00000138798 ENSG00000071051 ENSG00000148484 PMC7866785__F7 Regulation pathway of CASC19 in the radioresistance of NPC ENSG00000143799 ENSG00000198793 PMC3342364__F2 Molecular mechanisms mediating the regulatory effects of hypoxia ENSG00000108691 ENSG00000118520 ENSG00000038945 ENSG00000007171 PMC9272703__F4 N-Glycosylation and Inflammation; the Not-So-Sweet Relation ENSG00000168282 ENSG00000152127 ENSG00000073849 PMC5891174__F3 Crosstalk of DNA double‐strand break repair pathways in poly(ADP‐ribose) polymerase inhibitor treatment of breast cancer susceptibility gene 1/2‐mutated cancer ENSG00000012048 ENSG00000080345 ENSG00000051180 ENSG00000139618 PMC4283216__F1 GSK-3 family as therapeutic target for myocardial diseases ENSG00000137834 ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000105723 PMC5373538__F2 Proteomic characterization of epicardial-myocardial signaling reveals novel regulatory networks including a role for NFKB in epicardial EMT ENSG00000292348 ENSG00000105835 ENSG00000105426 ENSG00000163661 ENSG00000130508 ENSG00000168081 ENSG00000101425 PMC12052172__F4 Pathway network analysis based on genes annotated in eccDNAs ENSG00000159216 ENSG00000186716 PMC6627365__F2 Epidermal Growth Factor Receptor-dependent activation of the MAPK signaling pathway ENSG00000138798 ENSG00000146648 ENSG00000117322 PMC8750246__F1 AGEs-Induced and Endoplasmic Reticulum Stress/Inflammation-Mediated Regulation of GLUT4 Expression and Atherogenesis in Diabetes Mellitus ENSG00000245848 ENSG00000100219 ENSG00000127191 PMC6525811__F2 miRNAs that indirectly impact Alpha-syn without binding to its 3′-UTR ENSG00000078579 ENSG00000112561 PMC2396219__F2 PPARA and AMPK activities in the cancer cells exposed to energetic stress ENSG00000002330 ENSG00000169047 ENSG00000198793 PMC4967820__F2 Gene repertoire for sterol biosynthesis in unicellular holozoans ENSG00000132196 ENSG00000116133 ENSG00000172893 ENSG00000149809 ENSG00000104549 ENSG00000128602 PMC8439554__F1 Mechanisms Contributing to MAC Pathogenesis ENSG00000275331 ENSG00000162551 ENSG00000197594 ENSG00000111341 PMC6525811__F1 miR-7 playing a neuroprotective role in PD ENSG00000162711 ENSG00000173039 ENSG00000079999 PMC4382287__F2 Pathway as a Pharmacological Target for Herbal Medicines: An Investigation from Reduning Injection ENSG00000104365 ENSG00000185386 ENSG00000050748 ENSG00000173039 ENSG00000188130 ENSG00000073756 ENSG00000007171 PMC4577305__F2 The Secretory Pathway Kinases ENSG00000118972 ENSG00000140564 ENSG00000288499 ENSG00000152592 PMC6702336__F3 Summary of the role of the ERK1/2signaling pathway in CIRI ENSG00000116688 ENSG00000146648 PMC11923548__F10 Paeonia suffruticosa Andrews root extract ameliorates photoaging via regulating IRS1/PI3K/FOXO pathway ENSG00000149311 ENSG00000169047 ENSG00000198793 ENSG00000116717 ENSG00000079999 PMC4267483__F1 Noonan syndrome ENSG00000157764 ENSG00000110395 ENSG00000115904 ENSG00000108061 ENSG00000179295 PMC9045977__F3 Mitochondrial Dysfunction Pathway Alterations Offer Potential Biomarkers and Therapeutic Targets for Ovarian Cancer ENSG00000182511 ENSG00000213658 ENSG00000179091 PMC7268158__F2 The JAK/STAT system in graft-versus-host disease ENSG00000169248 ENSG00000162711 ENSG00000186810 ENSG00000111537 ENSG00000187140 ENSG00000189403 ENSG00000292357 ENSG00000026103 PMC7268158__F1 JAK/STAT System ENSG00000138378 ENSG00000111537 ENSG00000105397 ENSG00000117400 ENSG00000113520 PMC5771830__F5 Cancer cell metabolic changes linked to hyper-O-GlcNAcylation ENSG00000147162 ENSG00000198408 ENSG00000138798 ENSG00000136997 PMC5036249__F7 Proposed mechanistic scheme of CA4 suppressing the Wnt signalling pathway in colorectal cancer ENSG00000168036 ENSG00000146457 ENSG00000167434 PMC8301472__F2 Molecular Mechanisms of Resistance to Immune Checkpoint Inhibitors in Melanoma Treatment: An Update ENSG00000102962 ENSG00000151882 ENSG00000184451 ENSG00000168036 ENSG00000118520 ENSG00000100985 PMC4074217__F5 Comparison of apoptotic pathways and NLRP3 inflammasome activation ENSG00000162711 ENSG00000088888 ENSG00000116688 PMC6668984__F6 KEGG pathway enrichment analysis in signalling pathways ENSG00000101146 ENSG00000141480 ENSG00000115415 ENSG00000109320 ENSG00000291971 PMC3458933__F7 Schematic overview of the results from the present study indicating WNT-5A secretion from astrocytes and the WNT-5A-induced signaling pathway towards ERK1/2 regulating distinct aspects of the proinflammatory transformation of microglia ENSG00000100985 PMC3123876__F6 Profiling experiments and pathway analysis ENSG00000147488 ENSG00000274247 ENSG00000135960 ENSG00000125686 ENSG00000166278 ENSG00000108510 ENSG00000135373 PMC6225658__F2 Representative image of the anti-angiogenic potential of autophagy ENSG00000198300 PMC3507178__F3 Flow chart depicting the metabolic pathway of fatty acids in the liver of GH transgenic Amago based on 3′-tag digital gene expression profiling and comparison of serum triacylglycerol and glucose, and 3-hydroxybutyric acid ENSG00000151726 ENSG00000042832 ENSG00000170522 ENSG00000197977 ENSG00000165175 ENSG00000026103 PMC2759974__F1 MMTV mouse models and the diagnostic values of MMTV-like sequences in human breast cancer ENSG00000228716 ENSG00000134982 ENSG00000135446 ENSG00000177606 ENSG00000168036 ENSG00000152592 ENSG00000125084 PMC8539290__F2 Anti-Inflammatory and Anticancer Effects of Microalgal Carotenoids ENSG00000132906 ENSG00000262406 ENSG00000162692 ENSG00000127191 PMC9655983__F9 Src Family Kinases Facilitate the Crosstalk between CGRP and Cytokines in Sensitizing Trigeminal Ganglion via Transmitting CGRP Receptor/PKA Pathway ENSG00000108691 ENSG00000042832 ENSG00000163739 ENSG00000125538 PMC8983667__F1 Pseudoephedrine Nanoparticles Alleviate Adriamycin-Induced Reproductive Toxicity Through the GnRhR Signaling Pathway ENSG00000109163 ENSG00000164742 ENSG00000285007 ENSG00000087460 PMC7578381__F6 Functionally grouped network visualization for epigenetically upregulated and downregulated genes ENSG00000186074 ENSG00000170909 ENSG00000160883 ENSG00000081237 ENSG00000184363 ENSG00000274513 ENSG00000149781 ENSG00000186442 ENSG00000112195 ENSG00000089692 ENSG00000110934 ENSG00000239998 ENSG00000108405 ENSG00000262845 ENSG00000108759 ENSG00000118898 ENSG00000170423 ENSG00000185069 ENSG00000186832 ENSG00000123610 PMC8448728__F5 PIGG defines the Emm blood group system ENSG00000069943 ENSG00000135845 ENSG00000100564 ENSG00000197563 ENSG00000185808 ENSG00000255072 ENSG00000197121 ENSG00000165282 ENSG00000275600 ENSG00000142892 ENSG00000143315 ENSG00000163964 ENSG00000108474 ENSG00000060642 ENSG00000101464 ENSG00000124155 ENSG00000197858 ENSG00000136908 PMC5507646__F1 BRAF mutations in the context of mitogen‐activated protein kinase (MAPK) molecular alterations ENSG00000157764 ENSG00000047936 ENSG00000146648 PMC3388569__F3 Common biological pathways activated in OVCA cells in response to chemotherapeutic agents ENSG00000169291 ENSG00000123240 ENSG00000002330 ENSG00000134982 ENSG00000111837 PMC4987202__F1 Axotomy activates the Wallerian degeneration pathway for the selective elimination and degeneration of severed axons ENSG00000157064 PMC3388569__F2 Shared biological pathway activation between chemotherapeutic agent treatments ENSG00000002330 ENSG00000134982 ENSG00000102468 PMC5675569__F3 Network of selected factors influencing myofibroblast survival/resistance to apoptosis ENSG00000105329 ENSG00000138798 ENSG00000113140 ENSG00000168036 ENSG00000164305 ENSG00000154096 PMC6414158__F4 ceRNA regulatory network associated with the MAPK signaling pathway ENSG00000138032 PMC5891635__F1 Two working models explaining Sgg association with colorectal cancer (CRC) ENSG00000168036 ENSG00000125255 PMC3822531__F2 Regulation of Wnt/-catenin signalling pathway.(A) Wnt forms a ternary complex with Fz and Lrp5/6, which promotes stabilization of Beta-catenin, thereby activating the pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6612304__F1 An integrative model of the roles of mitochondrial metabolism in liver cancer stem cells ENSG00000136997 ENSG00000026508 ENSG00000171791 ENSG00000159399 PMC6446925__F1 AMPK Signaling Pathway ENSG00000284161 ENSG00000167658 PMC3756375__F2 Nerve growth factor (NGF) signaling in breast cancer cells ENSG00000102871 ENSG00000133134 PMC9449101__F1 Key Metabolic Regulator of Bone and Cartilage Health ENSG00000084774 PMC8335742__F9 Dimethyl itaconate inhibits LPS-induced microglia inflammation and inflammasome-mediated pyroptosis via inducing autophagy and regulating the Nrf-2/HO-1 signaling pathway ENSG00000278718 ENSG00000162711 ENSG00000150782 ENSG00000079999 PMC6214712__F1 Mitotic Gene Bookmarking: An Epigenetic Program to Maintain Normal and Cancer Cell Phenotypes ENSG00000102145 ENSG00000141867 ENSG00000159216 ENSG00000168214 ENSG00000285109 ENSG00000171794 ENSG00000129514 ENSG00000136826 ENSG00000102974 ENSG00000111642 PMC1754372__F2 Th1- and Th2-like lymphocytes, and the key regulatory cytokines and their interactions in SS ENSG00000111537 ENSG00000134982 ENSG00000125538 PMC7853129__F6 CD147 deficiency in T cells prevents thymic involution by inhibiting the EMT process in TECs in the presence of TGFB ENSG00000176692 ENSG00000291971 ENSG00000135605 PMC3199809__F1 The TGFB signaling pathway PMC8200556__F2 Genetic Determinants Highlight the Existence of Shared Etiopathogenetic Mechanisms Characterizing Age-Related Macular Degeneration and Neurodegenerative Disorders ENSG00000162594 ENSG00000254636 PMC3650458__F1 Simplified overview of classical bile acid synthesis pathway in mice ENSG00000167910 ENSG00000180432 ENSG00000122787 PMC11763988__F4 Antioxidant role of butyrate in promoting animal health ENSG00000181019 ENSG00000079999 PMC5584166__F4 Signaling pathways that can cross talk with TNT formation ENSG00000112561 PMC8139556__F1 PI3K Inhibition in the Treatment of Breast Cancer, Alone or Combined With Immune Checkpoint Inhibitors ENSG00000109452 ENSG00000198793 PMC11560440__F4 Pathogenesis of SjD PMC6605697__F7 Possible antifibrotic mechanism of exogenous hydrogen sulfide in diabetic cardiomyocytes ENSG00000168036 PMC3777178__F3 Multifunctional phosphorylated PDZ proteins integrate signaling pathways to control hyperplasia, neoplasia, and cell metastasis ENSG00000123374 PMC4508759__F1 Neurons versus herpes simplex virus: the innate immune interactions that contribute to a host–pathogen standoff ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000115415 ENSG00000157601 ENSG00000172936 ENSG00000135828 ENSG00000276561 ENSG00000164342 PMC4831356__F1 Schematic model illustrating O‐GlcNAc pathway and influence of glucose and O‐GlcNAcylation on chondrogenic differentiation ENSG00000147162 ENSG00000198408 PMC3576882__F4 NFKB: Roles and Regulation In Different CD4+ T cell subsets ENSG00000198793 PMC11837354__F1 Main metabolic pathway of catecholamine biosynthesis ENSG00000123454 PMC11940455__F5 Signaling pathway activated by EGFR and TRKB receptors resulting in cell proliferation ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8388553__F9 Kisspeptin-54 attenuates oxidative stress and neuronal apoptosis in early brain injury after subarachnoid hemorrhage in rats via GPR54/ARRB2/AKT/GSK3B signaling pathway ENSG00000141480 ENSG00000171791 PMC2668371__F9 The proposed model ENSG00000198793 PMC6914362__F10 Metabolic control of BRISC-SHMT2 assembly regulates immune signaling ENSG00000142166 PMC3625980__F7 FBXW7A attenuates inflammatory signalling by downregulating C/EBPD and its target gene Tlr4 ENSG00000148400 ENSG00000198793 ENSG00000136869 PMC11884102__F1 Signaling pathways in fibrotic processes involving macrophages ENSG00000198793 PMC7830660__F1 Immune evasion by NSVs ENSG00000115415 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC4564644__F1 Diagram showing the possible mechanism of serotonin mediated signaling pathway activated by BME during learning ENSG00000139287 ENSG00000102003 ENSG00000123908 PMC5107592__F1 Toll-like receptor signalling pathway ENSG00000183735 ENSG00000239732 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC12185857__F3 Fructose promotes systemic chronic inflammation ENSG00000162711 ENSG00000136869 ENSG00000265972 PMC7973006__F1 In stationary state, the aryl hydrocarbon receptor (AHR) is part of a complex composed by the 90kDa heat shock protein (HSP90), the co-chaperone p23 (p23) and the hepatitis B virus X-associated protein (XAP2/AIP/ARA9) ENSG00000106546 PMC11932893__F3 Regulatory mechanisms of AMPK in MASH-associated inflammatory response ENSG00000177169 ENSG00000168958 ENSG00000125538 ENSG00000198793 ENSG00000217128 ENSG00000096717 ENSG00000108840 PMC11932893__F2 Molecular mechanisms of AMPK-regulated lipid metabolism ENSG00000177169 ENSG00000112561 ENSG00000169710 ENSG00000265972 ENSG00000026103 PMC5537006__F1 Top Ingenuity Pathway Analysis networks associated with genes whose expression is altered by high levels of miRNA expression associated with both TP53 and CpG island methylator phenotypehigh and/or microsatellite instability ENSG00000167693 ENSG00000147649 ENSG00000159733 ENSG00000166025 ENSG00000126261 ENSG00000088002 ENSG00000035681 ENSG00000179958 ENSG00000198853 ENSG00000178301 ENSG00000197380 ENSG00000107130 ENSG00000136997 ENSG00000113761 ENSG00000168404 ENSG00000025293 ENSG00000184277 ENSG00000148843 ENSG00000132357 ENSG00000111450 ENSG00000023909 ENSG00000119121 ENSG00000273992 ENSG00000131019 ENSG00000156802 ENSG00000102699 ENSG00000080603 ENSG00000142149 ENSG00000142546 ENSG00000140743 ENSG00000169189 ENSG00000198729 ENSG00000180035 ENSG00000156831 ENSG00000110675 ENSG00000169490 ENSG00000048462 ENSG00000291928 ENSG00000137563 ENSG00000163815 ENSG00000161955 ENSG00000008988 ENSG00000105270 ENSG00000128283 ENSG00000062598 ENSG00000133134 ENSG00000284936 ENSG00000131931 ENSG00000262788 ENSG00000179918 ENSG00000178498 ENSG00000120910 ENSG00000244687 ENSG00000156110 ENSG00000186047 ENSG00000128482 PMC12234872__F2 Cellular senescence and other age-related mechanisms in the pathogenesis of OP ENSG00000107562 ENSG00000101460 ENSG00000099985 ENSG00000105329 ENSG00000197635 ENSG00000088305 ENSG00000163599 ENSG00000112561 ENSG00000140416 ENSG00000118785 ENSG00000272398 ENSG00000115271 ENSG00000165819 PMC3236328__F2 The differentiation hierarchy within the mammary epithelium and potential relationships with breast cancer subtypes ENSG00000104856 ENSG00000157404 ENSG00000272398 PMC9483046__F1 Research Progress on Exosomes in Osteonecrosis of the Femoral Head ENSG00000178860 ENSG00000174059 PMC3236328__F1 Main NFKB-activating pathways ENSG00000104856 ENSG00000157625 ENSG00000131323 ENSG00000127191 PMC7681022__F1 Allosteric inhibition of MTHFR prevents futile SAM cycling and maintains nucleotide pools in one-carbon metabolism PMC7526609__F2 IL-2 mediated JAK-STAT signaling pathway in COVID-19 associated male infertility.This figure shows IL-4 JAK-STAT Pathway and their effect on male infertility, during the event of infection by SARS-CoV-2 ENSG00000135218 ENSG00000168610 PMC8615515__F6 Vitamin-Containing Antioxidant Formulation Reduces Carcinogen-Induced DNA Damage through ATR/Chk1 Signaling in Bronchial Epithelial Cells In Vitro ENSG00000012048 ENSG00000175054 ENSG00000138356 PMC9034118__F1 Predictive modeling of resistance to SMO inhibition in a patient-derived orthotopic xenograft model of SHH medulloblastoma ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC3429940__F1 Optimizing treatments for lymphangioleiomyomatosis ENSG00000163914 ENSG00000123374 PMC6069177__F7 Phosphorylation of the HPV E6 PBM links cellular stress response signaling to E6 inhibition of p53 transcriptional activity ENSG00000149311 ENSG00000175054 PMC8392322__F3 Ups and Downs of STAT Inhibition in Acute Myeloid Leukemia ENSG00000122025 ENSG00000168610 PMC8392322__F1 Ups and Downs of STAT Inhibition in Acute Myeloid Leukemia ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000105639 ENSG00000168610 PMC4320493__F7 Proposed model of the distinct features of Hh signal transduction in insect, fish and mammal ENSG00000128602 PMC2807379__F8 Nephronophthisis: Disease Mechanisms of a Ciliopathy ENSG00000106571 ENSG00000128602 PMC2807379__F6 Nephronophthisis: Disease Mechanisms of a Ciliopathy ENSG00000084093 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC2807379__F4 Nephronophthisis: Disease Mechanisms of a Ciliopathy ENSG00000175115 ENSG00000113971 ENSG00000068885 ENSG00000164690 ENSG00000144061 PMC3554339__F1 Actions of Nec-1 and its derivatives in a mouse system ENSG00000111537 ENSG00000137275 ENSG00000102871 ENSG00000082512 ENSG00000083799 ENSG00000168040 ENSG00000127191 ENSG00000285379 PMC6096743__F5 Relationship between individual genes composing the ‘blood vessel development’ ontology group ENSG00000107562 ENSG00000185215 ENSG00000161381 ENSG00000182963 ENSG00000106511 ENSG00000137801 ENSG00000111145 ENSG00000182533 ENSG00000154133 ENSG00000116132 ENSG00000026508 ENSG00000172889 ENSG00000288297 ENSG00000170989 ENSG00000037280 ENSG00000171951 ENSG00000154096 ENSG00000150630 PMC6401500__F2 Activation of NFKB in ITME ENSG00000104856 ENSG00000149311 ENSG00000102871 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000138385 PMC12226124__F4 Association of the inflammasome cascade with AD immunopathology ENSG00000278718 ENSG00000162711 ENSG00000150782 ENSG00000163568 ENSG00000091592 PMC4955784__F1 Molecular and Genetic Inflammation Networks in Major Human Diseases ENSG00000162889 ENSG00000167601 ENSG00000140992 ENSG00000130741 ENSG00000145191 ENSG00000223367 ENSG00000070831 ENSG00000198793 ENSG00000170606 ENSG00000168036 ENSG00000168610 ENSG00000111725 ENSG00000187840 ENSG00000179295 ENSG00000111602 ENSG00000113812 ENSG00000165458 ENSG00000100941 ENSG00000179094 ENSG00000149554 ENSG00000146648 ENSG00000140443 PMC6548290__F1 MAPK and MST2/Hippo signaling, energy and glucose metabolism ENSG00000074800 ENSG00000171435 PMC10925886__F4 Lymphocyte behaviors and functions by the circadian clock ENSG00000153815 ENSG00000165030 ENSG00000137077 ENSG00000186716 ENSG00000126353 ENSG00000170989 PMC10925886__F3 Myeloid cell behaviors and functions by the circadian clock ENSG00000292348 ENSG00000081041 ENSG00000107562 ENSG00000137077 ENSG00000121966 PMC3552779__F1 Aerobic glycolysis, the citric acid cycle, and key glycolytic shunts ENSG00000180210 ENSG00000074800 ENSG00000092621 ENSG00000159399 ENSG00000152556 PMC2704241__F5 Hepatic methionine metabolism and GSH synthesis PMC6317189__F4 Targets molecules of bta-mir-182 involved in the apoptosis signaling pathway ENSG00000132906 ENSG00000153094 ENSG00000149260 ENSG00000067900 ENSG00000171791 PMC5713451__F1 Physiologic and oncogenic Hedgehog signaling ENSG00000128602 PMC2677399__F2 Nuclear Factor KB, Airway Epithelium, and Asthma ENSG00000104856 ENSG00000173039 PMC7557389__F9 Proposed pathway showing the effects of nanopriming with MWCNT–COOH on the membrane lipid metabolism of peatland boreal forest species in response to possible alleviation of seed dormancy and improved vigor ENSG00000146005 ENSG00000173599 ENSG00000198670 ENSG00000184207 PMC8229730__F2 New Insights of SF1 Neurons in Hypothalamic Regulation of Obesity and Diabetes ENSG00000168066 ENSG00000150907 ENSG00000168610 PMC6966427__F1 B-cell receptor pathway ENSG00000095585 ENSG00000239732 ENSG00000186716 ENSG00000198793 ENSG00000134070 ENSG00000197943 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000010671 PMC6631594__F2 In the absence of Hh signal, Patched1 (Ptch1) inhibits the Hh pathway through the modulation of the Smoothened (Smo) ENSG00000164690 ENSG00000128602 PMC3230808__F7 Regulation of CYP1A1 by capsaicin in Hepa-1c1c7 cells ENSG00000140465 ENSG00000196689 ENSG00000106546 PMC9259834__F1 Myostatin and its Regulation: A Comprehensive Review of Myostatin Inhibiting Strategies ENSG00000198793 ENSG00000134363 PMC4632748__F3 Tamoxifen pathway and possible mechanisms of endocrine resistance in breast cancer cells ENSG00000291971 ENSG00000146648 ENSG00000141456 PMC6334777__F4 Activating MAPK Pathway Mutations in LCH ENSG00000065361 ENSG00000126353 ENSG00000169032 PMC4632748__F7 Possible involvement of candidate microRNAs in tamoxifen resistance pathways, based on the present literature search and IPA analysis ENSG00000100234 ENSG00000115548 ENSG00000291971 ENSG00000105991 ENSG00000019186 ENSG00000120094 ENSG00000129514 ENSG00000076641 ENSG00000105810 ENSG00000171791 ENSG00000146648 ENSG00000141456 PMC3315189__F1 S-ADENOSYLMETHIONINE TREATMENT OF ALCOHOLIC LIVER DISEASE: A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED TRIAL ENSG00000151224 PMC3397897__F8 Schematic presentation of signaling pathways and their downstream targets that are affected by a feedback loop between hBVR and PKCD ENSG00000173599 PMC5601349__F1 Alternative pathways of gluconate-6P formation by dissimilation of glucose in Burkholderia ENSG00000111816 PMC4632748__F1 Simplified possible molecular signaling pathways (1 to 6) of estrogen (E) and estrogen receptors (ER) ENSG00000291971 ENSG00000146648 ENSG00000141456 PMC3039708__F3 T cell coinhibition in prostate cancer: new immune evasion pathways and emerging therapeutics ENSG00000134982 ENSG00000049768 PMC3039708__F2 T cell coinhibition in prostate cancer: new immune evasion pathways and emerging therapeutics ENSG00000115415 ENSG00000198793 ENSG00000172936 ENSG00000175104 PMC5360632__F1 Combined Role of Vitamin D status and CYP24A1 in the Transition to Systemic Lupus Erythematosus ENSG00000111012 ENSG00000019186 ENSG00000145321 PMC8217840__F1 LRRK2-NFATc2 Pathway Associated with Neuroinflammation May Be a Potential Therapeutic Target for Parkinson’s Disease PMC4872230__F5 Identification and Characterization of miRNAs in Chondrus crispus by High-Throughput Sequencing and Bioinformatics Analysis ENSG00000150991 PMC7072741__F10 Postulated differences in the CXCR4-LASP1-AKT1 signaling between breast cancer and CML ENSG00000107562 ENSG00000198793 ENSG00000099942 ENSG00000121966 PMC5796629__F2 ROS generation metabolomics, transcriptomics, and metabotranscriptomics ENSG00000104365 ENSG00000081041 ENSG00000291971 ENSG00000146469 ENSG00000102794 ENSG00000089041 ENSG00000171791 ENSG00000131096 ENSG00000102468 ENSG00000007171 ENSG00000163631 ENSG00000104327 ENSG00000150782 ENSG00000113520 ENSG00000136869 ENSG00000005381 ENSG00000139687 ENSG00000146648 PMC7425302__F2 Interferon G signaling pathway ENSG00000169245 ENSG00000163939 ENSG00000159128 ENSG00000111537 ENSG00000115415 ENSG00000138755 ENSG00000027697 ENSG00000125347 ENSG00000189079 ENSG00000166164 PMC7425302__F1 Cancer resistance to immunotherapy ENSG00000159128 ENSG00000111537 ENSG00000134982 ENSG00000027697 ENSG00000273686 PMC8353790__F1 Adiponectin in psoriasis and its comorbidities: a review ENSG00000162594 PMC8786287__F3 Metabolic adaptation of super-complexes ENSG00000128272 ENSG00000126461 PMC12245688__F3 Antitumor effects of HDACi ENSG00000116044 ENSG00000158828 ENSG00000128342 ENSG00000108821 ENSG00000230034 PMC3571454__F10 Models for intrinsic signaling by BST2 and for BST2 as a virus sensor ENSG00000172936 ENSG00000127191 PMC12245688__F2 Action of HDACi on immune cells ENSG00000138795 ENSG00000118520 ENSG00000112715 ENSG00000108821 ENSG00000196628 PMC6719619__F1 T-cell development ENSG00000109906 ENSG00000020633 ENSG00000107485 ENSG00000073861 PMC3877719__F1 Analysis with NIH DAVID, Princeton GO term finder and Ingenuity Pathway Analysis yield similar gene enrichments, biological processes and pathways.The high confidence hit list was also analyzed by IPA for biological pathway enrichment ENSG00000133083 ENSG00000104321 ENSG00000241553 ENSG00000108819 ENSG00000280908 ENSG00000242372 ENSG00000126247 ENSG00000171848 ENSG00000197943 ENSG00000198049 ENSG00000101333 ENSG00000167434 ENSG00000130726 PMC6521789__F6 Mammalian PUFA synthesis pathway showing the n-3 PUFA pathway and the n-6 PUFA pathway, including the enzymes responsible for the elongation and desaturation steps ENSG00000011007 ENSG00000134824 ENSG00000149485 ENSG00000102977 PMC8071059__F2 Priming effects of stress on NLRP3 inflammasome in microglia ENSG00000162711 ENSG00000150782 ENSG00000108691 ENSG00000125538 ENSG00000189403 ENSG00000277943 PMC4681988__F14 Aspirin blocks signaling pathway involved in platelet activation as laid out by our algorithm ENSG00000180210 ENSG00000127928 ENSG00000101146 ENSG00000127533 ENSG00000078369 ENSG00000148798 ENSG00000181104 ENSG00000095303 ENSG00000127955 ENSG00000182621 PMC4042208__F1 Stress signaling pathways activated by electrophiles ENSG00000128272 ENSG00000144895 ENSG00000079999 PMC9298969__F1 Glucagon-Like Peptide-1 Receptor Agonists as Potential Myelination-Inducible and Anti-Demyelinating Remedies ENSG00000150907 ENSG00000198793 PMC2966904__F7 Proposed scheme of the signaling pathway by TfR2 and HFE ENSG00000010704 ENSG00000140564 ENSG00000105697 PMC11675435__F3 Nrf2 signaling pathway in RCC ENSG00000134086 ENSG00000181555 ENSG00000079999 PMC11675435__F2 KEAP1–Nrf2-ARE pathway in constitutive condition and under oxidative stimuli ENSG00000100387 ENSG00000079999 PMC7246552__F1 Summary of methyl and methionine metabolism ENSG00000291507 ENSG00000173599 ENSG00000133027 PMC4135953__F10 The gene-to-gene networks of TLR3, TLR4, and poly(I·C) in mice immunized with UV-V after SARS-CoV challenge ENSG00000162711 ENSG00000081041 ENSG00000090104 ENSG00000134982 ENSG00000119508 ENSG00000115590 ENSG00000140279 ENSG00000148926 ENSG00000087074 ENSG00000167604 ENSG00000125347 ENSG00000162654 ENSG00000137801 ENSG00000011422 ENSG00000115415 ENSG00000170458 ENSG00000124882 ENSG00000138755 ENSG00000139289 ENSG00000136869 ENSG00000143333 ENSG00000130513 PMC6580702__F8 Negative regulators of NRF2 are found in autophagy ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000083290 ENSG00000023287 ENSG00000144848 ENSG00000145782 ENSG00000166471 ENSG00000057663 ENSG00000198925 ENSG00000079999 PMC2869521__F4 Solid tumors activate the NFKB pathway to maintain cell survival ENSG00000183735 ENSG00000144118 ENSG00000198793 ENSG00000083799 PMC2869521__F3 Constitutive NFKB pathway activation in multiple myeloma ENSG00000104856 ENSG00000111321 ENSG00000131323 ENSG00000083799 ENSG00000127191 PMC2869521__F1 Role of BCR signaling to NFKB in ABC DLBCL ENSG00000095585 ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000198793 ENSG00000175104 ENSG00000010671 ENSG00000198286 PMC1850774__F5 Convergence of signaling pathways ENSG00000002330 ENSG00000010810 ENSG00000168036 PMC2938013__F9 Dixdc1 is a critical regulator of DISC1 and embryonic cortical development ENSG00000166579 ENSG00000168036 ENSG00000150764 PMC2745765__F3 Linking the MGI and MouseCyc databases ENSG00000069482 ENSG00000133116 PMC6704701__F6 Illustration of the mechanism of SOX2 promotion of breast cancer cell migration ENSG00000111859 PMC12172487__F1 Metabolic pathway of Sia and EV-D usage ENSG00000159921 ENSG00000111726 ENSG00000164414 ENSG00000069482 ENSG00000064225 ENSG00000008513 ENSG00000115525 ENSG00000073849 ENSG00000126091 ENSG00000095380 ENSG00000144057 PMC8905560__F4 Prospective observational cohort study to identify inflammatory biomarkers for the diagnosis and prognosis of patients with sepsis ENSG00000170458 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000112149 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000062485 PMC3699383__F1 Apoptosis pathways ENSG00000002330 ENSG00000168040 PMC8205579__F7 Baicalin Magnesium Salt Attenuates Lipopolysaccharide-Induced Acute Lung Injury via Inhibiting of TLR4/NFKB Signaling Pathway ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC8385203__F10 Paeonol promotes Opa1-mediated mitochondrial fusion via activating the CK2Alpha-Stat3 pathway in diabetic cardiomyopathy ENSG00000168610 PMC7725927__F1 mTORC1 signaling pathway ENSG00000163435 PMC6756496__F3 Proposed signaling pathway in type II receptor cells ENSG00000185933 ENSG00000042832 ENSG00000070985 PMC8741844__F1 CircCCNB1 silencing acting as a miR-106b-5p sponge inhibited GPM6A expression to promote HCC progression by enhancing DYNC1I1 expression and activating the AKT/ERK signaling pathway ENSG00000171444 ENSG00000196839 PMC7156451__F9 Glycogen metabolism regulates macrophage-mediated acute inflammatory responses ENSG00000104812 ENSG00000115415 ENSG00000100504 PMC2570299__F3 Role of GalGlyNAcPVv in V ENSG00000069482 ENSG00000124357 ENSG00000281879 PMC10468807__F1 lncRNAs are involved in tumor cell lipid metabolism by targeting different signaling pathways ENSG00000151726 ENSG00000042832 ENSG00000198793 PMC4452864__F2 TGFB and ROS interplay ENSG00000140564 ENSG00000086991 PMC4835201__F10 A hypothetical diagram illustrates potential mechanisms in silicosis ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000127666 PMC6256271__F5 Targets of BA, JA, and BJ in the CD27 signaling pathway in lymphocytes ENSG00000139193 ENSG00000120868 PMC5876306__F3 MYC and HIF-1 regulate glucose metabolism ENSG00000136997 PMC7064563__F6 Metabolic pathways associated with EPS production in Phaeodactylum tricornutum ENSG00000124479 ENSG00000111816 PMC9327618__F3 Pre-clinical Studies Identifying Molecular Pathways of Neuroinflammation in Parkinson's Disease: A Systematic Review ENSG00000104856 ENSG00000125538 PMC10377333__F1 Indoleamine 2,3-Dioxygenase (IDO) Activity: A Perspective Biomarker for Laboratory Determination in Tumor Immunotherapy ENSG00000188676 ENSG00000106546 PMC12022316__F8 Mechanistic scheme of this study ENSG00000004975 ENSG00000165819 ENSG00000136231 PMC4528072__F2 Model for the mechanisms leading from impaired regulation of the alternative pathway to hemolytic uremic syndrome (HUS) ENSG00000110799 ENSG00000178726 PMC3310792__F8 Dengue Virus Infection Perturbs Lipid Homeostasis in Infected Mosquito Cells ENSG00000042832 ENSG00000173599 ENSG00000026103 PMC2677763__F7A Gene expression profiling analysis reveals arsenic-induced cell cycle arrest and apoptosis in p53-proficient and p53-deficient cells through differential gene pathways ENSG00000120915 ENSG00000169136 ENSG00000008394 ENSG00000162772 ENSG00000116157 ENSG00000176153 ENSG00000174607 ENSG00000079999 ENSG00000211445 ENSG00000128272 ENSG00000178573 ENSG00000156127 ENSG00000177606 ENSG00000167468 ENSG00000123268 PMC6520346__F6 Metabolomic analysis of in vitro effects of OPC-163493 in HepG2 cells PMC8191541__F2 Viperin Reveals Its True Function ENSG00000213928 ENSG00000088888 ENSG00000115415 ENSG00000134326 ENSG00000125347 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC4292778__F4 Gene network analysis of top HHT associated genes ENSG00000291983 ENSG00000135823 ENSG00000082512 ENSG00000153064 ENSG00000132478 ENSG00000085662 ENSG00000168040 ENSG00000089163 ENSG00000106459 ENSG00000187678 ENSG00000177425 PMC8560908__F1 The interplay between NFKB signaling and ARTD family members ENSG00000143799 ENSG00000104856 ENSG00000183735 ENSG00000088888 ENSG00000059378 ENSG00000178685 PMC9083113__F8 Age Related Changes in Muscle Mass and Force Generation in the Triple Transgenic (3xTgAD) Mouse Model of Alzheimer’s Disease ENSG00000142192 PMC11704404__F2 Autophagy initiation regulated by AMPK and mTORC1 ENSG00000177169 ENSG00000123395 ENSG00000083290 ENSG00000126775 ENSG00000198793 ENSG00000155792 ENSG00000167965 PMC11704404__F1 Schematic diagram illustrating the role of hepatic AMPK in regulating lipogenesis and lipolysis ENSG00000198793 ENSG00000169710 ENSG00000096717 PMC8138054__F3 Cellular and Molecular Mechanisms of Pristimerin in Cancer Therapy: Recent Advances ENSG00000070831 ENSG00000198793 ENSG00000170558 ENSG00000168036 ENSG00000117152 ENSG00000168610 ENSG00000136826 ENSG00000196411 ENSG00000026508 ENSG00000185591 ENSG00000164690 ENSG00000146648 ENSG00000123908 PMC11003747__SF3_2 I6pDel p-proteome network analysis ENSG00000118418 ENSG00000136937 ENSG00000117523 ENSG00000166503 ENSG00000139613 ENSG00000161813 ENSG00000187840 ENSG00000107581 PMC11003747__SF3_1 I-ASD p-proteome network analysis ENSG00000167258 ENSG00000141867 ENSG00000065978 ENSG00000119707 ENSG00000196504 ENSG00000167965 ENSG00000054118 ENSG00000158545 ENSG00000147274 ENSG00000107581 PMC5484669__F3 Signaling pathways that are key regulators of pluripotency in mESCs ENSG00000135111 ENSG00000128342 PMC7098997__F4 Changes in proteins involved in the oxidative stress metabolic pathway ENSG00000142655 ENSG00000124587 ENSG00000288217 ENSG00000101417 ENSG00000150787 ENSG00000164751 ENSG00000034693 PMC7098997__F3 Changes in proteins involved in carbon metabolism and oxidative stress metabolic pathway ENSG00000172005 ENSG00000091140 PMC3829115__F1 Schematic overview of TF signaling complexes ENSG00000003436 ENSG00000134982 PMC8560908__F5 The interplay between AKT signaling and ARTD family members ENSG00000143799 ENSG00000081913 ENSG00000150907 ENSG00000291803 ENSG00000041880 ENSG00000096717 PMC8560908__F4 The interplay between MAPK signaling and ARTD family members ENSG00000143799 ENSG00000172680 ENSG00000128272 ENSG00000107854 PMC8560908__F2 The interplay between JAK/STAT signaling and ARTD family members ENSG00000143799 ENSG00000171720 ENSG00000163840 ENSG00000115415 ENSG00000196591 ENSG00000111224 PMC8637879__F2 Mini-Review: GSDME-Mediated Pyroptosis in Diabetic Nephropathy ENSG00000278718 ENSG00000162711 ENSG00000265972 PMC4365493__F8 The signaling pathway through which MIF increases vascular permeability ENSG00000019582 ENSG00000198793 ENSG00000026508 ENSG00000057663 ENSG00000121966 PMC8294384__F6 Hepatic lipid metabolomics in response to heat stress in local broiler chickens breed (Huaixiang chickens) ENSG00000140505 ENSG00000130649 PMC2974170__F1 Diagram of TLR signaling pathways ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC2398704__F3 High and low pollen-hoarding strain bees ENSG00000127445 ENSG00000102309 PMC7535936__F5 Schematic outline of the Nodal signaling pathway in vertebrates ENSG00000160973 ENSG00000156574 ENSG00000130283 ENSG00000184344 PMC3364883__F2 Protein processing in endoplasmic reticulum is altered in Manf mutants ENSG00000128272 ENSG00000185591 ENSG00000198168 PMC10650070__F2 NFKB, MAPK and Oct-1 pathways for expression of Beta-defensins ENSG00000226275 ENSG00000172936 PMC12218123__F1 Folate metabolic pathway; connection between the folate cycle and methionine cycle ENSG00000116761 PMC3364883__F5 Gene expression alterations in Manf mutants with a linkage to Parkinson's disease ENSG00000132906 PMC3364883__F4 Changes in gene expression related to endocytosis in Manf mutants ENSG00000130164 ENSG00000136100 ENSG00000155792 ENSG00000171540 PMC8126649__F1 Biological Characteristics of Umbilical Cord Mesenchymal Stem Cells and Its Therapeutic Potential for Hematological Disorders ENSG00000135446 ENSG00000105810 ENSG00000026103 PMC4120774__F6 ATTENUATION OF MULTI-TARGETED PROLIFERATION-LINKED SIGNALING BY 3,3′-DIINDOLYLMETHANE (DIM): FROM BENCH TO CLINIC ENSG00000005882 ENSG00000198793 PMC4263370__F6 SteatoNet: The First Integrated Human Metabolic Model with Multi-layered Regulation to Investigate Liver-Associated Pathologies ENSG00000159346 ENSG00000136869 ENSG00000198670 ENSG00000285070 PMC4154379__F9 Tumor Necrosis FactorA Augments Matrix Metalloproteinase-9 Production in Skeletal Muscle Cells through the Activation of Transforming Growth Factor-Beta-activated Kinase 1 (TAK1)-dependent Signaling Pathway ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC4120774__F9 ATTENUATION OF MULTI-TARGETED PROLIFERATION-LINKED SIGNALING BY 3,3′-DIINDOLYLMETHANE (DIM): FROM BENCH TO CLINIC ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC3376488__F6 TRIF signal pathway ENSG00000177606 ENSG00000157625 ENSG00000168040 ENSG00000175104 ENSG00000164342 PMC5846637__F7 PD0332991-regulated gastric cancer cell signaling networks ENSG00000134982 PMC3376488__F5 MyD88 signal pathway ENSG00000172005 ENSG00000137265 ENSG00000172936 ENSG00000157625 ENSG00000175104 PMC3376488__F2 T-cell development and differentiation ENSG00000115904 ENSG00000168610 PMC7557985__F11 Differential mechanisms of CK2.3 in osteoblastogenesis and osteoclastogenesis ENSG00000164935 PMC3316585__F1 Formal Modeling and Analysis of the MAL-Associated Biological Regulatory Network: Insight into Cerebral Malaria ENSG00000172005 ENSG00000136869 ENSG00000010671 PMC7780025__F1 Mammalian Hippo‐YAP signaling network ENSG00000126016 ENSG00000186575 ENSG00000291971 ENSG00000197905 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC8641375__F7 Remimazolam Protects Against LPS-Induced Endotoxicity Improving Survival of Endotoxemia Mice ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000144566 PMC6196654__F1 Network of the two sets of top genes with P-value < 0.01 in the case–control and family-based analyses focusing on rare, deleterious variants ENSG00000123999 ENSG00000133019 ENSG00000118965 ENSG00000187535 ENSG00000112303 ENSG00000187720 ENSG00000175189 ENSG00000119650 ENSG00000089597 ENSG00000162188 ENSG00000148396 PMC11872695__F1 Illustrates the interplay between gut microbiota, ImP production, and cardiometabolic diseases ENSG00000105550 ENSG00000146648 PMC6260573__F7 Flavonoids downregulate mdr1 expression through wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000134982 ENSG00000168036 ENSG00000157240 PMC10499775__F1 Illustration of the Fas-FasL pathway ENSG00000198793 ENSG00000168040 ENSG00000064012 ENSG00000026103 PMC90529__F7 Genomic Profiling of the Response of Candida albicans to Itraconazole Treatment Using a DNA Microarray ENSG00000197429 ENSG00000167186 PMC7769200__F8 Schematic model illustrating the biological roles of the hsa_circ_0000714/miR-370-3p/RAB17 regulatory axis in A2780/PTX paclitaxel-resistant ovarian cancer cell ENSG00000135446 ENSG00000105810 ENSG00000124839 PMC11326265__F7 The effect of miR-1 loss on glycolytic and pentose phosphate enzymes and intermediates ENSG00000074800 ENSG00000011304 ENSG00000049239 ENSG00000141526 PMC3240145__F2 Intrinsic and extrinsic pathways of apoptosis ENSG00000168040 PMC4674284__F1 A working model of how the NLRC5 ubiquitination and deubiquitination feedforward loop shapes IKK/NFKB activity ENSG00000136869 ENSG00000175104 ENSG00000127191 PMC3563666__F4 Altered Cytokine Gene Expression in Peripheral Blood Monocytes across the Menstrual Cycle in Primary Dysmenorrhea: A Case-Control Study ENSG00000132906 ENSG00000170365 ENSG00000087245 ENSG00000171791 ENSG00000073756 ENSG00000064012 ENSG00000164305 ENSG00000204217 ENSG00000132170 PMC4559943__F1 Schematic diagram of the assembled modules to convert galactose to n-butanol ENSG00000197487 PMC3689941__F9 STAT3 pathway switching is induced by EMT during breast cancer progression ENSG00000291971 ENSG00000168610 ENSG00000146648 PMC8461988__F1 Interplay and cooperation of Helicobacter pylori and gut microbiota in gastric carcinogenesis ENSG00000226275 ENSG00000170458 ENSG00000136869 ENSG00000073756 ENSG00000146648 PMC8646045__F7 Activation of A7nAChR Protects Against Gastric Inflammation and Dysmotility in Parkinson’s Disease Rats ENSG00000177575 ENSG00000125538 ENSG00000129226 PMC3775430__F5 Model for possible sequence of genomic events in PCA progression ENSG00000157554 ENSG00000184012 PMC5543755__F5 Protein complex analysis ENSG00000111249 ENSG00000072134 ENSG00000119878 ENSG00000150672 ENSG00000182255 ENSG00000198576 ENSG00000132535 PMC5543755__F4 Merged mouse and rat network (mapped to human proteins) and overlapping Reactome pathways ENSG00000046889 ENSG00000198793 ENSG00000163394 ENSG00000198576 ENSG00000049283 ENSG00000130956 ENSG00000166278 ENSG00000025039 ENSG00000141562 ENSG00000095906 ENSG00000149295 ENSG00000062485 PMC7070911__F1 Metabolic pathway and mechanism of action of Clopidogrel ENSG00000165841 ENSG00000197408 PMC5999788__F2 Integration of actions of PKD1 and PKD3 in cardiac energy metabolism—a hypothetical scheme ENSG00000008710 ENSG00000135218 ENSG00000291971 ENSG00000061273 ENSG00000108840 PMC9337250__F4 Bile acids and sphingolipids in non-alcoholic fatty liver disease ENSG00000163914 ENSG00000170989 ENSG00000125910 ENSG00000267534 PMC9314780__F3 Pathobiology of the Klotho Antiaging Protein and Therapeutic Considerations ENSG00000118972 ENSG00000205221 ENSG00000133116 ENSG00000168036 ENSG00000140443 PMC9673322__F7 Inhibition of platelet activation suppresses reactive enteric glia and mitigates intestinal barrier dysfunction during sepsis ENSG00000125538 ENSG00000175104 PMC9337250__F2 Bile acids and sphingolipids in non-alcoholic fatty liver disease ENSG00000276559 ENSG00000167910 ENSG00000180432 ENSG00000115271 ENSG00000135929 PMC7699465__F1 Nelfinavir inhibits the Nrf1-dependent synthesis of proteasome subunits and inhibits the proteasome, leading to accumulation of misfolded proteins that activate IRE1A and PERK arms of the UPR ENSG00000128272 ENSG00000144895 ENSG00000101255 ENSG00000132646 ENSG00000198793 ENSG00000123374 ENSG00000168610 ENSG00000285069 ENSG00000106459 PMC3775430__F1 PI3K/PTEN/Akt pathway ENSG00000198793 PMC7222024__F4 Sugar and lipid metabolic pathways affected by oxygen availability ENSG00000135218 ENSG00000130164 ENSG00000073060 PMC5773247__F1 Wnt Signaling in Cardiovascular Disease: Opportunities and Challenges ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000120149 ENSG00000198793 ENSG00000177606 ENSG00000168036 ENSG00000113520 PMC9688074__F7 Long Noncoding RNAs in the Regulation of Cellular Immune Response and Inflammatory Diseases ENSG00000125538 ENSG00000168036 ENSG00000136869 PMC9688074__F6 Long Noncoding RNAs in the Regulation of Cellular Immune Response and Inflammatory Diseases ENSG00000101882 ENSG00000125538 ENSG00000136869 ENSG00000175104 PMC9688074__F8 Long Noncoding RNAs in the Regulation of Cellular Immune Response and Inflammatory Diseases ENSG00000162711 ENSG00000125538 PMC12027412__F9 Pathway enrichment analysis and protein–protein interaction among active components and common targets in prostate cancer ENSG00000277893 PMC6978272__F8 How CSF induced accumulation of endosomes, autophagosomes, and lysosomes, which led to increased intracellular AB accumulation ENSG00000142192 ENSG00000198382 ENSG00000121351 PMC12027412__F4 Component–target–pathway–disease network diagram ENSG00000168036 ENSG00000121879 PMC9688074__F1 Long Noncoding RNAs in the Regulation of Cellular Immune Response and Inflammatory Diseases ENSG00000136869 ENSG00000175104 PMC9688074__F3 Long Noncoding RNAs in the Regulation of Cellular Immune Response and Inflammatory Diseases ENSG00000162711 ENSG00000168610 PMC5412778__F2 Neural ectoderm and neural crest specification in deprivation of the external signals.A ENSG00000165556 ENSG00000164900 ENSG00000170365 ENSG00000164736 ENSG00000133937 ENSG00000185155 ENSG00000152977 ENSG00000135903 ENSG00000135480 PMC7729224__F2 Cyclic adenosine monophosphate (cAMP)-cAMP response element binding (CREB)-miR-21- programmed cell death protein 4 (PDCD4) axis ENSG00000198793 PMC2386254__F11 A Bacterial Cytotoxin Identifies the RhoA Exchange Factor Net1 as a Key Effector in the Response to DNA Damage PMC5949363__F7 Interaction between T follicular helper (Tfh) and B cells initiating synergetic effect of IL-21/IL-21R and CD40 ligand (CD40L)/CD40 to promote plasma cell differentiation and antibody production in EAE ENSG00000186716 ENSG00000173599 ENSG00000237834 PMC6289701__F2 Mammalian mTORC1-dependent ribosomal transcription ENSG00000101751 ENSG00000178573 ENSG00000198793 ENSG00000111642 PMC7729224__F3 Wnt/Beta-catenin-c-Myc-miR-17∼92 axis ENSG00000198793 ENSG00000168036 PMC7901767__F1 Evidence that a naturally occurring single nucleotide polymorphism in the RagC gene of Leishmania donovani contributes to reduced virulence ENSG00000130147 ENSG00000155792 PMC1636614__F8 Schema of Ang II-induced NFAT activation in cardiac myocytes ENSG00000039537 ENSG00000253506 ENSG00000138741 PMC5686148__F8 Working model ENSG00000123374 ENSG00000166851 PMC9250990__F1 T Cell Extracellular Traps: Tipping the Balance Between Skin Health and Disease ENSG00000239732 ENSG00000164430 ENSG00000111537 ENSG00000134982 PMC3042129__F8 Unified sample preparation protocol for proteomic and genomic profiling of cervical swabs to identify biomarkers for cervical cancer screening ENSG00000182718 ENSG00000160789 ENSG00000186395 ENSG00000164251 ENSG00000131747 ENSG00000073111 ENSG00000198598 ENSG00000164305 ENSG00000137807 ENSG00000138778 ENSG00000057149 ENSG00000074800 ENSG00000132646 ENSG00000164754 ENSG00000133119 ENSG00000139687 PMC9067156__F9 UDP‐glucose dehydrogenase expression is upregulated following EMT and differentially affects intracellular glycerophosphocholine and acetylaspartate levels in breast mesenchymal cell lines ENSG00000109814 ENSG00000124216 ENSG00000103066 PMC7865460__F1 Multiple myeloma (MM) cell metabolism compared to normal plasma cells PMC7865460__F3 General metabolic effects of MM-associated oncogenes ENSG00000178573 ENSG00000135446 ENSG00000136997 ENSG00000105810 ENSG00000118971 PMC4984448__F2 Modulating mitochondrial quality in disease transmission: towards enabling mitochondrial DNA disease carriers to have healthy children ENSG00000116688 ENSG00000158828 ENSG00000057663 PMC9177993__F1 Chromosomal synapsis defects can trigger oocyte apoptosis without elevating numbers of persistent DNA breaks above wild-type levels ENSG00000149311 ENSG00000175054 ENSG00000176635 ENSG00000054796 ENSG00000253729 PMC5131988__F2 Exploring Regulatory Mechanisms of Atrial Myocyte Hypertrophy of Mitral Regurgitation through Gene Expression Profiling Analysis: Role of NFAT in Cardiac Hypertrophy ENSG00000143248 ENSG00000059588 ENSG00000077044 ENSG00000109189 ENSG00000161970 ENSG00000176871 ENSG00000073921 ENSG00000169715 ENSG00000115875 ENSG00000162385 ENSG00000221823 ENSG00000197958 ENSG00000149273 ENSG00000271425 PMC10975175__F2 Heat stress triggers nitric oxide (NO) production and increases calcium levels ENSG00000161634 ENSG00000084092 ENSG00000062485 PMC5131988__F3 Exploring Regulatory Mechanisms of Atrial Myocyte Hypertrophy of Mitral Regurgitation through Gene Expression Profiling Analysis: Role of NFAT in Cardiac Hypertrophy ENSG00000221823 ENSG00000113196 ENSG00000150281 ENSG00000253506 ENSG00000285109 ENSG00000291971 ENSG00000128342 ENSG00000099991 PMC10889199__F1 Endothelial cell senescence ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000096717 PMC8275185__F11 Transcriptome Analysis of Chloris virgata, Which Shows the Fastest Germination and Growth in the Major Mongolian Grassland Plant ENSG00000213658 ENSG00000113558 ENSG00000171462 PMC4761146__F9 Schematic diagram depicting the proposed signaling pathway involved in interferon-induced transmembrane protein 1 (IFITM1) upregulation in SUM149 cells ENSG00000213928 ENSG00000105397 ENSG00000185885 PMC7683115__F6 lncRNA-miRNA regulation mechanism diagram based on the insulin signaling pathway ENSG00000171105 PMC7683115__F7 lncRNA-miRNA regulation mechanism diagram based on the AGE-RACE signaling pathway ENSG00000137193 ENSG00000168610 PMC1553448__F7 Transcript expression of BMP signaling pathway members ENSG00000107779 ENSG00000283060 ENSG00000204217 ENSG00000125968 ENSG00000172201 PMC11899777__F4 Comprehensive Review of Fc Gamma Receptors and Their Role in Systemic Lupus Erythematosus ENSG00000291971 ENSG00000163914 ENSG00000010671 PMC5153335__F1 KRAS pathway biology ENSG00000157764 ENSG00000198793 ENSG00000116237 PMC4374654__F3 Emerging regulators of the inflammatory process in osteoarthritis ENSG00000144895 ENSG00000125538 ENSG00000100219 PMC3936936__F1 Network of interactions between products of candidate genes from the QTL regions ENSG00000142627 ENSG00000142192 ENSG00000111537 ENSG00000135604 ENSG00000198793 ENSG00000173599 ENSG00000171608 ENSG00000122194 ENSG00000115009 ENSG00000182326 ENSG00000135919 PMC7218278__F1 “Confidence view” of the protein-protein interaction network on String.The thickness of the blue line between 2 nodes indicates the level of confidence of association between these 2 ENSG00000125249 ENSG00000011600 ENSG00000172216 ENSG00000137033 ENSG00000162924 ENSG00000043462 ENSG00000078898 ENSG00000132170 ENSG00000143418 ENSG00000136167 PMC7232545__F1 Anticancer mechanisms of matrine ENSG00000132906 ENSG00000087245 ENSG00000138795 ENSG00000002330 ENSG00000162337 ENSG00000138798 ENSG00000138794 ENSG00000198793 ENSG00000168036 ENSG00000127191 ENSG00000168610 ENSG00000164305 ENSG00000057663 ENSG00000135446 ENSG00000132646 ENSG00000189403 ENSG00000123374 ENSG00000105810 ENSG00000100985 ENSG00000145782 ENSG00000064012 ENSG00000146648 PMC9237220__F1 Different Immunoregulation Roles of Activin A Compared With TGFB ENSG00000198793 PMC7545984__F2 Pro-fibrotic roles of the GSK-3B signaling network in fibrosis ENSG00000141480 ENSG00000168036 PMC3257109__F3 BMP signaling in motor neurons ENSG00000038382 ENSG00000170365 ENSG00000106683 PMC8560861__F8 Model summarizing the pathway described in this study along with known effects of CCL20 and CXCL8 signaling in the context of cancer ENSG00000163464 ENSG00000169429 ENSG00000168610 ENSG00000115009 PMC6935755__F2 Ragulator complex in SEGAs ENSG00000134248 ENSG00000169047 ENSG00000023287 ENSG00000108443 ENSG00000167965 ENSG00000188186 ENSG00000116039 ENSG00000136888 ENSG00000089685 ENSG00000123154 ENSG00000132906 ENSG00000177169 ENSG00000157764 ENSG00000116586 ENSG00000177058 ENSG00000155876 ENSG00000149357 ENSG00000114573 ENSG00000100554 ENSG00000132356 ENSG00000111725 ENSG00000187840 ENSG00000115592 ENSG00000181929 ENSG00000106617 ENSG00000263014 ENSG00000204673 ENSG00000109270 ENSG00000143882 PMC7545984__F1 Anti-fibrotic roles of the GSK-3B signaling network in fibrosis ENSG00000118515 ENSG00000168036 ENSG00000171791 ENSG00000142082 PMC10982457__F1 Viral RNA‐driven peripheral serotonin reduction impairs neurocognition by directly dampening vagal signaling ENSG00000130234 ENSG00000164342 PMC3982501__F4 Receptor tyrosine kinase (RTK) signaling pathway is frequently hit by lentiviral vector (LV) integration ENSG00000157764 ENSG00000198793 PMC10035551__F1 Regulation of PD-1 and PD-L1 expression in sepsis ENSG00000291603 ENSG00000134982 PMC10960957__F5 Ferrihydrite-mediated methanotrophic nitrogen fixation in paddy soil under hypoxia ENSG00000261701 PMC6695603__F1 Epidermal growth factor receptor (EGFR) pathway in non-small cell lung cancer (NSCLC) ENSG00000138798 ENSG00000198793 ENSG00000146648 ENSG00000178568 PMC6751247__F7 Schematic description of TLR7-mediated enhancement of CD8+ T cell function ENSG00000111537 ENSG00000198793 ENSG00000137265 ENSG00000172936 PMC6695603__F4 Epidermal Growth Factor Receptor (EGFR) Pathway, Yes-Associated Protein (YAP) and the Regulation of Programmed Death-Ligand 1 (PD-L1) in Non-Small Cell Lung Cancer (NSCLC) ENSG00000136807 ENSG00000065361 ENSG00000109321 ENSG00000138798 ENSG00000146648 ENSG00000178568 PMC8764384__F1 Critical Roles of Proteostasis and Endoplasmic Reticulum Stress in Atrial Fibrillation ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8568770__F1 Endocannabinoid System Unlocks the Puzzle of Autism Treatment via Microglia ENSG00000117480 ENSG00000125245 ENSG00000196689 PMC7798029__F1 Suppressive activity of MDSCs induced by the TLR2 and TLR4 signaling pathways ENSG00000143546 ENSG00000117400 ENSG00000196154 ENSG00000172936 ENSG00000136869 ENSG00000118520 ENSG00000168610 PMC5613704__F1 Acute and chronic effects of plasma Ang II, aldosterone and EO on brain angiotensinergic pathways PMC6036268__F6 Pectin oligosaccharides (POS) downregulates the expression of nuclear factor-kappa B (NFKB) and COX-2 by binding toll-like receptor 4 (TLR4) ENSG00000183735 ENSG00000187554 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000184216 ENSG00000164342 PMC7312564__F2 Proliferation and Differentiation of Adipose-Derived Stem Cells in Neovascularization and Angiogenesis ENSG00000245848 ENSG00000039537 PMC10030845__F2 Inflammasome and pyroptosis in autoimmune liver diseases ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC10030845__F1 Inflammasome and pyroptosis in autoimmune liver diseases ENSG00000278718 ENSG00000162711 ENSG00000174885 ENSG00000091592 ENSG00000172936 ENSG00000136869 ENSG00000091106 PMC7982061__F2 Notch1 signaling pathway and Notch1 inhibitors ENSG00000112576 ENSG00000140564 ENSG00000128917 ENSG00000136997 ENSG00000184916 ENSG00000137845 ENSG00000090932 PMC4091181__F10 The role of GABARAPL1/GEC1 in autophagic flux and mitochondrial quality control in MDA-MB-436 breast cancer cells ENSG00000109819 ENSG00000139112 PMC6082390__F2 PC1/3 activity is essential to the leptin–melanocortin pathway ENSG00000198576 ENSG00000115138 ENSG00000166603 PMC6205410__F1 Four hyperglycemia-induced pathogenic pathways which are related to overproduction of ROS and inflammation progression in atherosclerosis ENSG00000136869 ENSG00000132693 PMC11460135__F8 Inhibition of HOXC11 by artesunate induces ferroptosis and suppresses ovarian cancer progression through transcriptional regulation of the PROM2/PI3K/AKT pathway ENSG00000167468 ENSG00000123388 PMC6205410__F2 Downstream products of ROS promote endothelial cells (ECs) dysfunction in atherosclerosis ENSG00000198793 ENSG00000127528 PMC9204952__F9 Genome-wide association mapping and genomic prediction for pre‑harvest sprouting resistance, low Alpha-amylase and seed color in Iranian bread wheat ENSG00000110934 ENSG00000221818 PMC8126329__F1 Analysis of the Protein–Protein Interaction Network Identifying c-Met as a Target of Gigantol in the Suppression of Lung Cancer Metastasis ENSG00000114554 ENSG00000150093 ENSG00000184363 ENSG00000057294 ENSG00000102854 ENSG00000138964 ENSG00000291561 ENSG00000291657 ENSG00000172037 ENSG00000291681 ENSG00000240184 ENSG00000148498 ENSG00000134755 ENSG00000099889 ENSG00000144283 ENSG00000075275 ENSG00000076716 ENSG00000071991 PMC8001214__F3 Mechanisms of aging-associated salt-sensitive hypertension and crosstalk between Wnt noncanonical pathway and angiotensin II (Ang II)-induced vasoconstrictive pathway ENSG00000047410 ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000125538 ENSG00000168036 PMC11120279__S1 FDT vaccine with the ability to activate systemic immunity for tumor inhibition ENSG00000171855 ENSG00000153208 ENSG00000134982 PMC5490578__F7 Simplified diagram of the lipid metabolism canonical pathway ENSG00000189058 ENSG00000042832 ENSG00000005421 ENSG00000100979 PMC4865921__F9 Schematic summary of the results ENSG00000130164 ENSG00000164305 PMC8463275__F2 Cyclin-dependent kinases-based synthetic lethality: Evidence, concept, and strategy ENSG00000167258 ENSG00000157404 ENSG00000198793 ENSG00000277273 ENSG00000136807 ENSG00000012048 ENSG00000135446 ENSG00000136997 ENSG00000161513 ENSG00000123374 ENSG00000105810 ENSG00000026103 ENSG00000138385 PMC12001097__F4 Inflammatory cytokines and activation of PI3K/Akt pathway by Yiqi Jiedu Formula in recurrent Herpes Simplex Keratitis: Experimental and network pharmacology evidence ENSG00000104365 ENSG00000109320 ENSG00000213341 ENSG00000171791 ENSG00000112715 ENSG00000121879 ENSG00000012048 ENSG00000066468 ENSG00000128052 ENSG00000113520 ENSG00000136869 ENSG00000108821 ENSG00000077782 ENSG00000146648 PMC4951304__F1 Cdc7 is a potent anti-cancer target in pancreatic cancer due to abrogation of the DNA origin activation checkpoint ENSG00000135446 ENSG00000050165 ENSG00000136997 ENSG00000123374 ENSG00000105810 PMC2564829__F7 Activated neutrophils induce an hMSH2-dependent G2/M checkpoint arrest and replication errors at a (CA)13-repeat in colon epithelial cells ENSG00000175054 PMC1971124__F4 BDCA2/FcERIG Complex Signals through a Novel BCR-Like Pathway in Human Plasmacytoid Dendritic Cells ENSG00000095585 ENSG00000291603 ENSG00000187796 ENSG00000213658 ENSG00000010810 ENSG00000186716 PMC10956371__F1 UPR signaling pathway ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8085316__F2 Adapting T Cell Receptor Ligand Discrimination Capability via LAT ENSG00000213658 PMC11555832__F4 Facilitating tumor cells recognition by innate immune cells ENSG00000239732 ENSG00000164430 ENSG00000172936 ENSG00000136869 ENSG00000107201 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000276561 ENSG00000164342 PMC11555832__F3 Resistance to PD-1 blockade in CRC ENSG00000273686 PMC9240433__F8 Breast Meat Fatty Acid Profiling and Proteomic Analysis of Beijing-You Chicken During the Laying Period ENSG00000151726 ENSG00000135218 ENSG00000115425 ENSG00000110244 ENSG00000101470 ENSG00000173208 ENSG00000164305 ENSG00000157184 ENSG00000221823 ENSG00000205678 ENSG00000097021 ENSG00000093144 ENSG00000102893 ENSG00000115361 ENSG00000146070 ENSG00000075239 ENSG00000281500 PMC3928697__F5 Proposed pathway of CD33 siglec-mediated suppression of cellular function in Leishmania infection ENSG00000111537 ENSG00000268500 PMC7836502__F6 Production of PA and DGPP by different pathways and interconversion reactions mediated by phosphorylation and dephosphorylation ENSG00000168748 ENSG00000124102 ENSG00000164879 ENSG00000178538 ENSG00000173599 ENSG00000198670 ENSG00000074410 PMC3070284__F2 Endothelial growth factor receptor (EGFR) signaling pathway ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8814392__F2 Restoration of miR-223-3p expression in aged mouse uteri with Samul-tang administration ENSG00000101670 ENSG00000130957 ENSG00000161905 ENSG00000122420 ENSG00000149380 ENSG00000128918 ENSG00000176597 ENSG00000196839 ENSG00000172543 ENSG00000060558 ENSG00000140287 ENSG00000084110 ENSG00000003137 ENSG00000109861 ENSG00000127080 ENSG00000092621 ENSG00000196549 ENSG00000103723 ENSG00000196371 ENSG00000163734 ENSG00000275544 ENSG00000131400 PMC7399786__F7 Roles of miR-33a and its target genes in prostate (top) and breast cancer (bottom), and the underlying mechanisms ENSG00000138029 ENSG00000137193 ENSG00000163577 ENSG00000047936 ENSG00000168615 ENSG00000164778 PMC6242703__F1 Simplified diagram of transcriptional pathways and targets for intervention for AUD treatment PMC6592474__F8 Endoplasmic reticulum stress is involved in spiral ganglion neuron apoptosis following chronic kanamycin-induced deafness ENSG00000128272 ENSG00000100219 ENSG00000127191 PMC4950926__F6 Schematic presentation of mechanisms of actions of CTS ENSG00000122180 ENSG00000129152 ENSG00000140416 PMC7688141__F8 Nucleotide de novo synthesis increases breast cancer stemness and metastasis via cGMP-PKG-MAPK signaling pathway ENSG00000136826 PMC5955995__F4 MAPK Signaling pathway showing expression pattern of DEGs in Ladakhi and Sahiwal cows ENSG00000087095 ENSG00000027075 ENSG00000123240 ENSG00000157764 ENSG00000138798 ENSG00000130159 ENSG00000100485 ENSG00000081189 ENSG00000225950 ENSG00000185386 ENSG00000141503 ENSG00000170458 ENSG00000067606 ENSG00000111837 ENSG00000177606 ENSG00000188130 ENSG00000196712 ENSG00000135517 ENSG00000026103 PMC8269279__F6 Roles of Pseudophosphatases in Disease ENSG00000198842 ENSG00000198252 ENSG00000170558 ENSG00000048740 ENSG00000109670 PMC1069621__F5 Two models for coupling of circadian and cell cycles ENSG00000175054 ENSG00000164053 ENSG00000111602 PMC3525180__F3 Some perifosine-specific genes are connected by common pathways leading to MAPK signalling pathway and apoptosis ENSG00000107186 ENSG00000285485 ENSG00000140443 ENSG00000114738 PMC8251784__F4 In search of biomarkers for leprosy by unraveling the host immune response to Mycobacterium leprae ENSG00000116031 ENSG00000167207 PMC4694853__F8 Non-canonical adenosinergic pathway led by CD38 in human melanoma cells induces suppression of T cell proliferation ENSG00000198793 PMC4891982__F4 Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage ENSG00000151376 ENSG00000122966 ENSG00000173599 ENSG00000172005 ENSG00000082212 PMC6790656__F3 Biological applications of light‐induced dimerization systems ENSG00000166278 PMC12115990__F3 TRIM25 regulates the RIG-I- and MDA5-mediated antiviral and TRAF2/TNFA signaling pathways ENSG00000088888 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000121060 ENSG00000141569 PMC7139810__F7 Reciprocal link between the serine biosynthesis pathway (SBP) and MYC oncogene ENSG00000128272 ENSG00000092621 ENSG00000135069 PMC12115990__F2 Biological functions of TRIM25 in SARS-CoV-2 infection and cancer cell survival ENSG00000213928 ENSG00000088888 ENSG00000178573 ENSG00000167468 ENSG00000112561 ENSG00000121060 ENSG00000276561 ENSG00000079999 PMC1774101__F4 Proposed framework for recruitment of T cells into the gut mucosa by activated CD40L+ platelets ENSG00000183625 ENSG00000162692 PMC4055851__F2 Resistance to anti-EGFR moAbs in mCRC ENSG00000198793 ENSG00000146648 PMC3616974__F6 Epigenetic Upregulation of lncRNAs at 13q14.3 in Leukemia Is Linked to the In Cis Downregulation of a Gene Cluster That Targets NF-kB ENSG00000198553 ENSG00000102753 ENSG00000186047 ENSG00000157625 PMC6779808__F6 Network analysis from RNA seq ENSG00000142794 ENSG00000003756 ENSG00000164002 ENSG00000129654 ENSG00000187522 ENSG00000134744 ENSG00000130751 ENSG00000173530 ENSG00000108312 PMC8869286__F1 Identification of Targetable Liabilities in the Dynamic Metabolic Profile of EGFR-Mutant Lung Adenocarcinoma: Thinking beyond Genomics for Overcoming EGFR TKI Resistance ENSG00000019991 ENSG00000130164 ENSG00000169710 ENSG00000146648 PMC6156122__F2 Pathways to retinal regeneration ENSG00000213658 ENSG00000138083 ENSG00000168036 ENSG00000139352 PMC10260623__F1 Schematic of the clock pathway ENSG00000105516 PMC8044762__F2 cGas-STING activation pathway ENSG00000197594 ENSG00000198925 PMC8372643__F2 HIF1Alpha-PFKFB3 Pathway in Diabetic Retinopathy ENSG00000180210 ENSG00000128917 PMC5600417__F1 GO biological process and KEGG pathway enrichment analyses of the differentially modulated proteins at 6 and/ or 12 h of treatment with A233 peptide ENSG00000138029 ENSG00000131495 ENSG00000165280 ENSG00000124802 ENSG00000085662 ENSG00000158869 ENSG00000127884 ENSG00000088888 ENSG00000173559 ENSG00000139579 ENSG00000189043 ENSG00000116584 ENSG00000075239 ENSG00000159399 PMC8372643__F3 HIF1Alpha-PFKFB3 Pathway in Diabetic Retinopathy ENSG00000180210 ENSG00000134982 PMC2212359__F5 HToll and TNFR-1 signaling pathways ENSG00000102871 ENSG00000172936 ENSG00000175104 ENSG00000127191 PMC209410__F1 The EXT proteins and HS biosynthesis ENSG00000069482 ENSG00000182197 ENSG00000151348 ENSG00000062485 PMC9682092__F4 LncRNAs involved in regulating the RIG-I signaling pathway ENSG00000088888 ENSG00000276561 PMC9682092__F3 LncRNAs involved in regulating the RIG-I signaling pathway ENSG00000183735 ENSG00000088888 ENSG00000253352 ENSG00000276561 PMC6262346__F1 Metabolic pathways involved in glucose, fructose, and xylose catabolism in B ENSG00000197713 ENSG00000153574 ENSG00000093217 PMC209410__F2 A working model of mammalian bone development ENSG00000182197 ENSG00000128602 ENSG00000163501 ENSG00000151348 PMC9682092__F2 LncRNAs involved in regulating the RIG-I signaling pathway ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000111837 ENSG00000121060 ENSG00000276561 ENSG00000142166 PMC8884404__F1 Molecular Pathways of Pyroptosis in Atherosclerosis ENSG00000278718 ENSG00000162711 ENSG00000163568 PMC9682092__F1 LncRNAs involved in regulating the RIG-I signaling pathway ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000121060 ENSG00000276561 PMC3227927__F1 Signaling pathways and effects of EGFR ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000146648 PMC8998691__F3 MicroRNAs Expression in Response to rhNGF in Epithelial Corneal Cells: Focus on Neurotrophin Signaling Pathway ENSG00000185634 ENSG00000002330 ENSG00000070831 ENSG00000169047 ENSG00000095015 ENSG00000171791 ENSG00000169032 ENSG00000099942 ENSG00000121879 ENSG00000137764 ENSG00000111348 ENSG00000179295 ENSG00000078900 ENSG00000197943 ENSG00000124181 ENSG00000162889 ENSG00000157764 ENSG00000100906 ENSG00000173039 ENSG00000143933 ENSG00000160691 ENSG00000185652 ENSG00000117020 ENSG00000177189 ENSG00000177606 ENSG00000175104 ENSG00000184216 ENSG00000134313 PMC9368823__F2 Cell Signaling Pathways and Non-Coding RNAs by Baicalein in Different Cancers ENSG00000168209 ENSG00000164327 PMC8998691__F2 MicroRNAs Expression in Response to rhNGF in Epithelial Corneal Cells: Focus on Neurotrophin Signaling Pathway ENSG00000174197 PMC9368823__F1 Cell Signaling Pathways and Non-Coding RNAs by Baicalein in Different Cancers ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000174804 ENSG00000168036 ENSG00000196628 PMC4126464__F10 Metabolic redistribution in Synechococcus sp ENSG00000122966 ENSG00000172005 ENSG00000197429 PMC3728221__F8 Working model for the synergistic effect of TPL and ATF on tumour cells ENSG00000145604 ENSG00000132906 ENSG00000168040 ENSG00000164305 PMC8872821__F1 Chemokine CCL1 as a therapeutic target for pulmonary fibrosis: comments on ‘The chemokine CCL1 triggers an AMFR‒SPRY1 pathway that promotes differentiation of lung fibroblasts into myofibroblasts and drives pulmonary fibrosis’ ENSG00000108702 ENSG00000164056 ENSG00000159461 PMC8280127__F8 HOTAIRM1 working mechanism ENSG00000146376 ENSG00000153094 ENSG00000067900 ENSG00000171791 PMC8069526__F5 RNAs that regulate nonhomologous end-joining (NHEJ) ENSG00000133812 PMC4277354__F6 ReNE: A Cytoscape Plugin for Regulatory Network Enhancement ENSG00000132906 ENSG00000084093 ENSG00000184845 ENSG00000108179 ENSG00000284774 ENSG00000073578 ENSG00000158828 ENSG00000127955 ENSG00000064692 ENSG00000149295 ENSG00000115317 PMC6604468__F7 MUC17 inhibits the progression of human gastric cancer by limiting inflammatory responses ENSG00000163914 ENSG00000169876 ENSG00000113722 PMC5705614__F1 The core elements of the mammalian Hippo signaling pathway ENSG00000104814 ENSG00000011566 ENSG00000144560 ENSG00000114978 ENSG00000168067 ENSG00000150457 ENSG00000131023 PMC5705614__F3 Schematic depicting the mechanical regulation of the mammalian Hippo signaling pathway ENSG00000126016 PMC5705614__F2 Schematic depicting the hormonal regulation of the mammalian Hippo signaling pathway ENSG00000126016 ENSG00000134982 ENSG00000198670 PMC5705614__F4 Schematic depicting the metabolic regulation of the mammalian Hippo signaling pathway ENSG00000126016 PMC4467156__F12 New chemical inhibitor of angiogenesis and tumorigenesis that targets the VEGF signaling pathway upstream of Ras ENSG00000066468 ENSG00000077782 PMC7801429__F2 An ER signaling pathway network identified by IMPALA using Loi breast cancer gene expression data ENSG00000160789 ENSG00000171105 ENSG00000005339 ENSG00000081237 ENSG00000291971 ENSG00000134308 ENSG00000131747 ENSG00000169047 ENSG00000196591 ENSG00000101266 ENSG00000213341 ENSG00000197045 ENSG00000121774 ENSG00000168610 ENSG00000164305 ENSG00000160691 ENSG00000179295 ENSG00000163558 ENSG00000186716 ENSG00000177606 ENSG00000015285 ENSG00000124181 ENSG00000146648 ENSG00000120896 PMC7385185__F11 The two-way communication between AMs and AECs in LPS-induced airway inflammation ENSG00000125538 ENSG00000136869 PMC7503879__F6 Insulin/FoxO signaling pathway in silkworm diapause eggs at onset of diapause ENSG00000005882 PMC4939711__F1 Oncogenic signalling and nutrient availability influence cell metabolism ENSG00000131473 ENSG00000136997 ENSG00000169710 ENSG00000115419 PMC4213571__F2 Model depicting Tax-induced shuttling, localization and activation of canonical and noncanonical NFKB signaling pathways ENSG00000104856 ENSG00000136878 ENSG00000063978 ENSG00000123240 ENSG00000083799 ENSG00000120913 ENSG00000056736 ENSG00000175104 PMC4939711__F3 Complex, compartmentalized pathways of NADPH production ENSG00000284320 ENSG00000180210 ENSG00000065911 ENSG00000100714 ENSG00000136997 ENSG00000163738 ENSG00000078237 PMC8102819__F2 Immunopathology of Acute Kidney Injury in Severe Malaria ENSG00000162692 PMC4939711__F2 Catabolic pathways support metabolism during nutrient stress ENSG00000157764 ENSG00000062485 PMC4568025__F2 Interaction network for human CIBLIN transcriptional regulators ENSG00000185513 ENSG00000118579 ENSG00000138136 ENSG00000063322 ENSG00000102908 ENSG00000118526 ENSG00000137270 ENSG00000105085 ENSG00000126003 ENSG00000125398 ENSG00000136997 ENSG00000125686 ENSG00000104973 ENSG00000116990 ENSG00000112182 ENSG00000116793 ENSG00000105996 ENSG00000188994 ENSG00000109705 ENSG00000178860 ENSG00000173917 ENSG00000141026 ENSG00000167034 ENSG00000106459 ENSG00000005302 ENSG00000107249 ENSG00000139154 ENSG00000285485 ENSG00000038945 ENSG00000119715 ENSG00000188786 ENSG00000104856 ENSG00000175221 ENSG00000265763 ENSG00000125740 ENSG00000100146 ENSG00000072364 ENSG00000124782 ENSG00000070444 ENSG00000176692 ENSG00000077150 ENSG00000169840 ENSG00000164758 ENSG00000005513 ENSG00000130675 ENSG00000078699 ENSG00000111269 ENSG00000157259 ENSG00000168505 ENSG00000106536 ENSG00000283060 ENSG00000113068 ENSG00000154655 ENSG00000125968 ENSG00000167635 ENSG00000143390 ENSG00000116044 ENSG00000109320 ENSG00000143013 ENSG00000119596 ENSG00000174332 ENSG00000105698 ENSG00000104064 ENSG00000118495 ENSG00000050344 ENSG00000008838 ENSG00000114315 ENSG00000131196 PMC7394371__F3 Gene expression profile analysis of the rabbit retinal vein occlusion model ENSG00000133895 ENSG00000226275 ENSG00000002330 ENSG00000213658 ENSG00000156110 ENSG00000148798 ENSG00000111837 ENSG00000127191 ENSG00000111816 ENSG00000062485 PMC3644335__F2 Cryptosporidium parvum scavenges LDL-derived cholesterol and micellar cholesterol internalized into enterocytes ENSG00000138075 ENSG00000130164 ENSG00000015520 ENSG00000143921 PMC10525124__F2 Oxidative Stress in Liver Pathophysiology and Disease ENSG00000137857 ENSG00000140279 ENSG00000086991 ENSG00000079999 PMC3941591__F5 ‘Ephrin Receptor Signaling’ was the second canonical IPA pathway induced in LR rats upon FST exposure ENSG00000160691 PMC5569090__F11 Schematic presentation of the mechanism for shell biomineralization mediated by the TGFB/BMP signaling pathway in molluscs ENSG00000170365 ENSG00000095739 ENSG00000204217 PMC3941591__F4 Top Ingenuity networks of genes whose expression was significantly altered in the hippocampus upon FST exposure ENSG00000135439 ENSG00000136854 ENSG00000105290 ENSG00000292366 ENSG00000102189 ENSG00000162139 ENSG00000170365 ENSG00000276618 ENSG00000101773 ENSG00000163914 ENSG00000136518 ENSG00000159335 ENSG00000164506 ENSG00000172466 ENSG00000107929 ENSG00000100376 ENSG00000123091 ENSG00000137275 ENSG00000183691 ENSG00000103942 ENSG00000182195 ENSG00000070756 ENSG00000182175 ENSG00000153944 ENSG00000167535 ENSG00000291631 ENSG00000111052 PMC11772949__F3 The RLR adaptor MAVS mediated by protein palmitoylationIn the RLR signaling pathway, CPT1A interacts with ZDHHC4 to promote MAVS palmitoylation at Cys79 ENSG00000174165 ENSG00000088888 ENSG00000153786 ENSG00000137275 ENSG00000136247 ENSG00000064012 PMC4133210__F1 Subverting ER-Stress towards Apoptosis by Nelfinavir and Curcumin Coexposure Augments Docetaxel Efficacy in Castration Resistant Prostate Cancer Cells ENSG00000128272 ENSG00000144895 ENSG00000101255 ENSG00000100219 PMC6972624__F10 Proposed model ENSG00000100387 ENSG00000136997 PMC10758544__F9 Byakangelicol suppresses TiPs-stimulated osteoclastogenesis and bone destruction via COX-2/NFKB signaling pathway ENSG00000100985 ENSG00000131196 ENSG00000143387 PMC3564018__F10 Stress-suppressed genes involved in antigen presentation and synapse formation ENSG00000116815 ENSG00000111537 ENSG00000170458 ENSG00000232326 ENSG00000136869 ENSG00000126353 PMC10243851__F1 Clinical, genetic, and immune landscape of meningioma in patients with NF2-schwannomatosis ENSG00000026508 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC7477642__F2 Selected pathways relevant for plausible salvaging of residual ovarian function in primary ovarian insufficiency ENSG00000104899 ENSG00000157404 ENSG00000198793 ENSG00000051180 PMC8771833__F4 Slit/Robo Signaling pathway in Bone Metabolism ENSG00000145147 ENSG00000184347 ENSG00000154134 ENSG00000185008 PMC3149740__F5 Mammals have two distinct but ultimately converging pathways to apoptosis ENSG00000100290 ENSG00000002330 ENSG00000102871 ENSG00000168040 ENSG00000135116 ENSG00000104081 PMC2898443__F1 The eukaryotic 80 S initiation pathway ENSG00000106682 ENSG00000163435 ENSG00000100664 PMC8771833__F5 Slit/Robo Signaling pathway in Bone Metabolism ENSG00000145147 ENSG00000070831 ENSG00000170558 ENSG00000168036 ENSG00000154134 PMC7403683__F1 Conditional reprogramming (CR) culture system and the potential molecular mechanisms of CR ENSG00000033327 ENSG00000113070 ENSG00000198793 ENSG00000163914 ENSG00000026508 ENSG00000168036 PMC7530640__F1 Role of microglia and canonical NLRP3 inflammasome in Alzheimer's disease ENSG00000278718 ENSG00000162711 ENSG00000125538 ENSG00000189403 PMC6197541__F1 Associated cell signaling pathway and related potential therapeutic areas PMC5293201__F1 Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective ENSG00000181867 ENSG00000146648 ENSG00000079999 PMC8990295__F3 Cancer metabolism challenges genomic instability and clonal evolution as therapeutic targets ENSG00000151012 ENSG00000167468 ENSG00000077463 ENSG00000142082 PMC7884075__F4 GWAS hits in the IGF-1 pathway ENSG00000124102 ENSG00000120833 ENSG00000120210 ENSG00000167994 ENSG00000197081 ENSG00000129965 ENSG00000112964 ENSG00000169047 ENSG00000120211 ENSG00000155903 ENSG00000168610 ENSG00000160691 ENSG00000137558 ENSG00000178188 ENSG00000167964 ENSG00000121853 ENSG00000177548 ENSG00000140443 PMC8257068__F1 Prospect of CDK4/6 Inhibitors in Triple-Negative Breast Cancer ENSG00000135446 ENSG00000158796 ENSG00000123374 ENSG00000105810 PMC9468713__F7 Anti-Osteoclast Effect of Exportin-1 Inhibitor Eltanexor on Osteoporosis Depends on Nuclear Accumulation of IKBA–NFKB p65 Complex ENSG00000175104 ENSG00000131196 ENSG00000143387 PMC5866851__F2 Visual description of the IL-31 and IL-33 cascades leading to the activation of the genes and the proteins involved in the development of inflammatory disorders ENSG00000108691 ENSG00000081041 ENSG00000145623 ENSG00000137033 ENSG00000102970 ENSG00000172936 ENSG00000106178 PMC7847103__F1 Subgroup specific actionable molecular pathway in MB ENSG00000134982 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC7547805__F2 Regulatory mechanisms of TEAD in cancer biology ENSG00000167601 ENSG00000136997 ENSG00000197905 ENSG00000100985 ENSG00000150457 ENSG00000131023 ENSG00000196628 ENSG00000115461 PMC5557384__F5 Insulin-induced PI3K-Akt and MAPK network in hepatocytes ENSG00000104812 ENSG00000131473 ENSG00000155506 ENSG00000002330 ENSG00000106070 ENSG00000198793 ENSG00000169047 ENSG00000111713 ENSG00000115904 ENSG00000204673 ENSG00000160691 ENSG00000164916 PMC10536768__F4 Innate Immune Response to Viral Vectors in Gene Therapy ENSG00000164430 ENSG00000172936 ENSG00000131323 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC3590592__F6 Proposed schematic representation of Wnt5a/Beta-catenin signaling in keloid pathogenesis ENSG00000134982 ENSG00000168036 PMC10536768__F3 Innate Immune Response to Viral Vectors in Gene Therapy ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000172936 ENSG00000276561 PMC10536768__F2 Innate Immune Response to Viral Vectors in Gene Therapy ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000172936 ENSG00000136869 ENSG00000276561 ENSG00000142166 PMC2195651__F1 Fas (death receptor) signaling pathway and its inhibition ENSG00000168040 ENSG00000026103 PMC2531163__F3 Developmental signaling pathways ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000128602 PMC4919901__F2 Allergic Mechanisms of Eosinophilic Oesophagitis ENSG00000105329 ENSG00000134982 ENSG00000197971 PMC11772949__F8 Modulation of JAK-STAT signaling by palmitoylationIn the JAK-STAT signaling pathway, JAK1, JAK2, STAT1, STAT3, and STAT5A can be palmitoylated ENSG00000175893 ENSG00000135218 ENSG00000153786 ENSG00000184307 ENSG00000160446 ENSG00000131095 ENSG00000136247 ENSG00000163812 ENSG00000156599 ENSG00000168610 ENSG00000142166 ENSG00000169245 ENSG00000115415 ENSG00000099904 PMC3146606__F2 PARP function in base excision repair and consequences of PARP inhibition ENSG00000149311 ENSG00000012048 ENSG00000051180 ENSG00000227345 ENSG00000138385 PMC9448771__F8 Graphical abstract. NAT10 functions as a negative regulator of neutrophil pyroptosis and a protective factor in sepsis ENSG00000177169 ENSG00000162711 ENSG00000135372 PMC12092303__F2 Molecular targets and mechanisms of O-GlcNAcylation in the central nervous system ENSG00000147162 ENSG00000198408 ENSG00000198793 ENSG00000164690 ENSG00000168610 PMC3022188__F1 Rationale for dual treatment targeting the IGF-1R signaling pathway in RMS ENSG00000169047 ENSG00000198793 ENSG00000140443 PMC11772949__F5 RLRs induced by protein palmitoylationNLRP3 palmitoylation is induced by ZDHHC7 but suppressed by ABHD17A at Cys126 ENSG00000162711 ENSG00000131238 ENSG00000135218 ENSG00000167207 ENSG00000153786 ENSG00000160446 ENSG00000129968 ENSG00000284099 ENSG00000169710 ENSG00000106100 ENSG00000156599 ENSG00000159714 PMC9052535__F1 Integrated regulation of chondrogenic differentiation in mesenchymal stem cells and differentiation of cancer cells ENSG00000139219 ENSG00000170365 ENSG00000281324 ENSG00000125398 ENSG00000168214 ENSG00000162337 ENSG00000134982 ENSG00000157766 ENSG00000168036 ENSG00000128602 ENSG00000160691 ENSG00000110693 PMC11772949__F7 Pattern recognition receptor signaling by palmitoylation ENSG00000278718 ENSG00000162711 ENSG00000150782 ENSG00000188706 ENSG00000153786 ENSG00000175048 ENSG00000156599 PMC4605373__F4 Apoptosis response pathway ENSG00000110330 ENSG00000002330 ENSG00000105327 ENSG00000282905 ENSG00000102871 ENSG00000119969 ENSG00000164305 ENSG00000160049 ENSG00000146072 ENSG00000136997 ENSG00000168310 ENSG00000135116 ENSG00000026103 ENSG00000132906 ENSG00000104365 ENSG00000196954 ENSG00000269335 ENSG00000173039 ENSG00000065559 ENSG00000213341 ENSG00000168040 ENSG00000127191 ENSG00000276561 ENSG00000226275 ENSG00000177606 ENSG00000131323 ENSG00000258643 PMC11772949__F6 Pattern recognition receptor signaling by palmitoylation ENSG00000041353 ENSG00000164430 ENSG00000135218 ENSG00000088888 ENSG00000188706 ENSG00000153786 ENSG00000070831 ENSG00000180776 ENSG00000172936 ENSG00000106100 ENSG00000156599 PMC12092303__F1 Main physiological functions of O-GlcNAc in the central nervous system ENSG00000147162 ENSG00000198408 ENSG00000168610 PMC5733947__F4 miR-155-5p and miR-200a-3p greatly influence TLR4 signaling pathways ENSG00000243414 ENSG00000188379 ENSG00000104365 ENSG00000109320 ENSG00000269335 ENSG00000173039 ENSG00000169032 ENSG00000150455 ENSG00000183735 ENSG00000198189 ENSG00000066336 ENSG00000263528 ENSG00000177606 ENSG00000112984 ENSG00000125538 ENSG00000172936 ENSG00000131323 ENSG00000105810 ENSG00000074266 ENSG00000175104 PMC3364444__F1 N-BPs may modulate myeloma progression through their effects on the mevalonate pathway and directly on MM plasma cells, bone marrow cells and immune cells in the bone marrow ENSG00000163914 PMC5312381__F7 MicroRNA-126 inhibits colon cancer cell proliferation and invasion by targeting the chemokine (C-X-C motif) receptor 4 and Ras homolog gene family, member A, signaling pathway ENSG00000100852 ENSG00000121966 PMC9502927__F1 Targeting Ceramides and Adiponectin Receptors in the Islet of Langerhans for Treating Diabetes ENSG00000100422 PMC8658460__F10 Crosstalk between E-Cadherin/Beta-Catenin and NFKB Signaling Pathways: The Regulation of Host-Pathogen Interaction during Leptospirosis ENSG00000137673 ENSG00000168036 PMC10136030__F4 In the nucleus, TERT performs both canonical (elongates telomeric ends) and non-canonical functions (participates in the regulation of gene expression) ENSG00000149311 ENSG00000175054 ENSG00000164362 PMC10136030__F3 TERT is involved in major signaling pathways and participates in regulation of gene expression ENSG00000002330 ENSG00000164362 PMC3686618__F6 Main signaling pathways supposed to be activated in MEC exposed to either E ENSG00000169245 ENSG00000226275 ENSG00000169429 ENSG00000172936 ENSG00000136869 ENSG00000115009 PMC10136030__F2 Classification of BCL-2 family proteins and their role in the regulation of the internal pathway of apoptosis ENSG00000100290 ENSG00000002330 ENSG00000135116 ENSG00000104081 PMC10136030__F1 Structure and functions of telomeres ENSG00000166340 ENSG00000149311 ENSG00000175054 ENSG00000164362 ENSG00000128513 PMC7436626__F1 Role of H2S in lung inflammation ENSG00000125538 ENSG00000079999 PMC8232755__F7 DLX Genes: Roles in Development and Cancer ENSG00000113161 ENSG00000168036 ENSG00000185591 PMC3003905__F5 Spontaneous-fusion-mediated cell reprograming is controlled by Beta-catenin levels in ESCs and not by their proliferation ENSG00000154342 ENSG00000168036 ENSG00000166278 PMC3744901__F9 Regulation of RB/E2F pathway ENSG00000135446 ENSG00000138798 PMC4313578__F3 Therapeutic Targeting of Autophagy: Potential and Concerns in Treating Cardiovascular Disease ENSG00000117525 ENSG00000150907 ENSG00000155792 ENSG00000167965 PMC6728578__F9 Key proteins involved in the DNA damage response (DDR) following DNA double-strand breaks (DSBs) ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 PMC8005589__F1 Rationale to target mechanistic target of rapamycin (mTOR) in renal cell carcinoma (RCC) ENSG00000134086 PMC3520048__F2 Summary of the role of the mammalian target of rapamycin (mTOR) signaling pathway in the development of tuberous sclerosis complex (TSC) and inhibition by mTOR inhibitors ENSG00000169047 ENSG00000284161 ENSG00000164327 PMC7704201__F1 In the insulin signalling pathway, insulin attaches to insulin receptors triggering its dimerization and the intracellular autophosphorylation of their tyrosine residues, which constitute an attachment for IRS proteins ENSG00000124102 ENSG00000169047 PMC5064357__F6 Novel IRS-1-associated protein, DGKζ regulates GLUT4 translocation in 3T3-L1 adipocytes ENSG00000169047 ENSG00000143398 ENSG00000058866 PMC7704201__F3 Nrf2/Keap1/ARE pathway in T2DM ENSG00000178573 ENSG00000079999 PMC5969374__F4 Disrupted signaling pathways in GCB-DLBCL ENSG00000198793 ENSG00000136997 ENSG00000145321 ENSG00000171791 ENSG00000273936 ENSG00000267534 PMC9103477__F1 Comprehensive Investigation of Steroidogenic Signaling in Classical and New Experimental Cell Models of Adrenocortical Carcinoma ENSG00000109163 ENSG00000185231 PMC6111036__F11 D5R mutation induces dilated cardiomyopathy that is related to oxidative stress ENSG00000079999 PMC5969374__F5 Disrupted signaling pathways in ABC-DLBCL ENSG00000105369 ENSG00000186716 ENSG00000198793 ENSG00000137265 ENSG00000172936 ENSG00000010671 ENSG00000198286 PMC3230300__F2 Mucins in the Pathogenesis of Breast Cancer: Implications in Diagnosis, Prognosis and Therapy ENSG00000138798 ENSG00000146648 PMC3866868__F2 Nodal pathway activity in the determination of L–R asymmetry ENSG00000143768 ENSG00000156574 ENSG00000164093 PMC5244336__F9 The mechanisms by which PRRSV infection upregulated miR-373 expression and miR-373 facilitated PRRSV replication ENSG00000213928 ENSG00000134070 ENSG00000185591 ENSG00000125347 ENSG00000184216 ENSG00000142166 PMC8508344__F1 Estrogens and the Schrödinger’s Cat in the Ovarian Tumor Microenvironment ENSG00000108786 ENSG00000203859 PMC8775994__F3 Photic Entrainment of the Circadian System ENSG00000142178 ENSG00000177606 ENSG00000132326 ENSG00000179094 PMC5346293__F2 Signal pathway integration that regulates Hsp90 expression ENSG00000023734 ENSG00000284774 ENSG00000115415 ENSG00000168610 PMC7356240__F1 Macrophage migration inhibitory factor (MIF) mediates immune response crosstalk in dengue pathogenesis ENSG00000019582 ENSG00000026508 ENSG00000100985 ENSG00000121966 PMC7985549__F1 Several ligands on the cell surface stimulate the production of PIP3 (phosphatidylinositol trisphosphate) by PI3K ENSG00000134982 ENSG00000168036 ENSG00000146648 PMC6120164__F1 Network of “Target-Pathway” in osteosarcoma (OS) based on the collected data from – ENSG00000143799 ENSG00000157933 ENSG00000146872 ENSG00000030066 ENSG00000107443 ENSG00000101052 ENSG00000172795 ENSG00000069667 ENSG00000120742 ENSG00000128052 ENSG00000084733 ENSG00000108256 ENSG00000125266 ENSG00000168807 ENSG00000088179 ENSG00000108960 ENSG00000136478 ENSG00000144815 ENSG00000092847 ENSG00000164543 ENSG00000025039 ENSG00000099194 ENSG00000086015 ENSG00000285281 ENSG00000127334 ENSG00000285121 ENSG00000107854 ENSG00000151239 ENSG00000112378 ENSG00000146648 ENSG00000184216 PMC4928587__F5 Proposed model for the role of PALB2 in linking BRCA1 with BRCA2 and RAD51 in a pathway of HR ENSG00000012048 ENSG00000083093 ENSG00000051180 ENSG00000139618 PMC4001855__F1 Glycosylation of the nuclear pore ENSG00000147162 ENSG00000198408 PMC11946485__F1 PI3K signaling pathway inhibition and antitumor immune synergistic therapy strategy ENSG00000049768 ENSG00000168610 PMC11993743__F9 The potential of the SA8-E6-12 antibody cocktail to modulate immune responses activated by S100A8 ENSG00000143546 ENSG00000172936 ENSG00000136869 PMC8273570__F1 Three modes of IL-6R signaling and their associated intracellular pathways ENSG00000115904 ENSG00000168610 PMC6163404__F1 Brief overview of canonical and non-canonical nuclear factor kappa-light-chain-enhancer of activated B cells (NFKB) activation pathways ENSG00000104856 ENSG00000173039 PMC9068921__F7 Mechanism graph of the regulatory role of circ_0000811 in cerebral ischemic vertigo ENSG00000115415 PMC8668291__F1 Plant-Derived Chinese Medicine Monomers on Ovarian Cancer via the Wnt/Beta-Catenin Signaling Pathway: Review of Mechanisms and Prospects ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11946485__F5 Development of PI3K inhibitors represents a promising strategy to enhance the efficacy of cancer vaccines through the modulation of immune responses ENSG00000134982 ENSG00000186716 ENSG00000113520 ENSG00000126353 PMC2887830__F2 Regulation of intracellular Stat3 signalling ENSG00000087245 ENSG00000107562 ENSG00000122691 ENSG00000100985 ENSG00000168610 PMC11946485__F2 Regulatory role of PI3K signaling pathway in immune cell function ENSG00000002330 ENSG00000186716 ENSG00000168610 PMC11619421__F6 PPI network of associated pain-related genes enrichments in KEGG pathways and tissue expression ENSG00000140992 ENSG00000065989 ENSG00000169071 ENSG00000168036 ENSG00000138326 ENSG00000155974 ENSG00000100346 ENSG00000185313 ENSG00000157240 ENSG00000161681 ENSG00000040933 ENSG00000136997 ENSG00000119614 ENSG00000152208 ENSG00000220205 ENSG00000162552 ENSG00000138795 ENSG00000107404 ENSG00000156049 ENSG00000136535 ENSG00000065361 ENSG00000081248 ENSG00000163902 ENSG00000173786 ENSG00000174804 ENSG00000167658 ENSG00000186111 ENSG00000157005 ENSG00000072803 ENSG00000087460 ENSG00000291973 ENSG00000197461 ENSG00000123360 ENSG00000104327 ENSG00000100151 ENSG00000152192 ENSG00000148660 ENSG00000169676 ENSG00000063660 ENSG00000105737 ENSG00000132692 ENSG00000205927 ENSG00000188763 ENSG00000168646 ENSG00000069966 PMC9270260__F12 Novel antiproliferative PKCAlpha-Ras-ERK signaling axis in intestinal epithelial cells ENSG00000115904 ENSG00000152689 ENSG00000125968 PMC5950532__F6 Protein-protein interaction analysis of HOXA13-related genes in the first four Kyoto Encyclopedia of Genes and Genomes pathways ENSG00000172380 ENSG00000288335 ENSG00000088256 ENSG00000164751 ENSG00000132170 ENSG00000157240 ENSG00000131779 ENSG00000128710 ENSG00000049130 ENSG00000148660 ENSG00000144118 ENSG00000026508 ENSG00000196914 ENSG00000162928 ENSG00000113790 ENSG00000145349 ENSG00000146648 PMC8922271__F5 Organelle interfaces by ER‐resident E3s ENSG00000135655 ENSG00000120925 ENSG00000149218 ENSG00000109133 ENSG00000198833 ENSG00000186480 ENSG00000107566 ENSG00000184787 ENSG00000099203 PMC11638664__F6 Schematic synthesis of data and hypothesis ENSG00000134982 ENSG00000168036 ENSG00000146648 ENSG00000172238 PMC8491218__F3 Pathway‐extended gene expression signatures integrate novel biomarkers that improve predictions of patient responses to kinase inhibitors ENSG00000167601 ENSG00000070193 ENSG00000065618 ENSG00000137270 ENSG00000171791 ENSG00000124762 ENSG00000112290 ENSG00000159216 ENSG00000076554 ENSG00000078900 ENSG00000150907 ENSG00000220205 ENSG00000105810 ENSG00000155760 ENSG00000140443 ENSG00000143995 ENSG00000159173 ENSG00000138795 ENSG00000155886 ENSG00000099864 ENSG00000183395 ENSG00000124216 ENSG00000136960 ENSG00000176463 ENSG00000115263 ENSG00000112208 ENSG00000187955 ENSG00000115009 ENSG00000175792 ENSG00000104856 ENSG00000140564 ENSG00000115904 ENSG00000164399 ENSG00000122194 ENSG00000106331 ENSG00000106546 ENSG00000104368 ENSG00000168003 ENSG00000165841 ENSG00000129946 ENSG00000166501 ENSG00000110013 ENSG00000128342 ENSG00000162188 ENSG00000171105 ENSG00000142627 ENSG00000086696 ENSG00000081041 ENSG00000135100 ENSG00000109320 ENSG00000174804 ENSG00000120800 ENSG00000167333 ENSG00000113073 ENSG00000073756 ENSG00000285221 ENSG00000196337 ENSG00000172935 ENSG00000071564 ENSG00000162733 ENSG00000010810 ENSG00000145321 ENSG00000075891 ENSG00000184371 ENSG00000164690 ENSG00000100985 ENSG00000204217 ENSG00000023839 ENSG00000105287 ENSG00000155850 ENSG00000150630 PMC10380296__F7 Transcriptional Modulation Reveals Physiological Responses to Temperature Adaptation in Acrossocheilus fasciatus ENSG00000177455 ENSG00000124102 ENSG00000002330 ENSG00000143878 ENSG00000186716 ENSG00000169047 ENSG00000121058 ENSG00000152430 PMC10380296__F6 Transcriptional Modulation Reveals Physiological Responses to Temperature Adaptation in Acrossocheilus fasciatus ENSG00000179091 ENSG00000138798 ENSG00000127948 PMC8491218__F1 Pathway‐extended gene expression signatures integrate novel biomarkers that improve predictions of patient responses to kinase inhibitors ENSG00000145362 ENSG00000076716 ENSG00000081051 ENSG00000023839 ENSG00000196233 ENSG00000106331 ENSG00000155657 ENSG00000123908 ENSG00000140416 PMC10380296__F5 Significantly DEGs identified by KEGG in protein digestion and absorption pathways (ko04974) ENSG00000196531 ENSG00000141086 ENSG00000086730 PMC2839260__F1 Schematic depiction of the signalling pathways stimulated by cholecystokinin (CCK) activation of the CCK1 receptor ENSG00000162889 ENSG00000169291 ENSG00000198793 ENSG00000146648 ENSG00000114738 PMC7985550__F1 PI3K signaling pathway and related target drugs in endothelial cells ENSG00000198793 PMC7072849__F9 Visual summary of the main findings of the study ENSG00000111057 ENSG00000133937 ENSG00000214513 ENSG00000170558 ENSG00000156574 ENSG00000168036 ENSG00000129514 ENSG00000103241 ENSG00000164736 ENSG00000185155 ENSG00000129654 ENSG00000243709 ENSG00000147869 ENSG00000164690 ENSG00000149922 PMC6909953__F2 E-cigarette aerosols induce unfolded protein response in normal human oral keratinocytes ENSG00000128272 ENSG00000159461 ENSG00000165280 ENSG00000127022 ENSG00000100219 ENSG00000171791 ENSG00000127191 PMC12052884__F1 Metformin in gynecological disorders: pathogenic insights and therapeutic implications ENSG00000198793 ENSG00000136869 ENSG00000096717 PMC7307862__F2 Various classes of lncRNAs ENSG00000183072 ENSG00000074266 ENSG00000164532 ENSG00000089225 PMC4117608__F6 Israeli Acute Paralysis Virus: Epidemiology, Pathogenesis and Implications for Honey Bee Health ENSG00000110700 ENSG00000008438 ENSG00000169021 ENSG00000139343 ENSG00000167552 ENSG00000140854 ENSG00000134884 ENSG00000164120 ENSG00000196396 ENSG00000117410 ENSG00000198818 ENSG00000163882 ENSG00000058600 ENSG00000149136 ENSG00000112303 ENSG00000177606 ENSG00000072110 ENSG00000159352 ENSG00000163636 ENSG00000127948 ENSG00000135250 ENSG00000084774 PMC4856760__F8 Working model of the regulation of the type I interferon and NFKB signaling pathway by TRIM9s ENSG00000183735 ENSG00000164430 ENSG00000088888 PMC7985550__F3 PI3K signaling pathway and related target drugs in vascular smooth muscle cells PMC4473797__F1 E3 Ubiquitin Ligases Pellinos as Regulators of Pattern Recognition Receptor Signaling and Immune responses ENSG00000170458 ENSG00000172936 ENSG00000276561 ENSG00000184216 PMC5582844__F7 Proposed model depicting cross-talk between Gq-coupled GPCRs and CLEC-2 pathways ENSG00000047410 ENSG00000108861 ENSG00000197943 PMC3334516__F4 TGFB signaling pathway members and potential pathway member LRG1 ENSG00000039537 ENSG00000163914 ENSG00000067900 PMC6820534__F6 Supposed mechanism ENSG00000070831 ENSG00000136068 PMC3361678__F1 Many host factors are involved at each step of the HCV life cycle, which starts with virus binding to its specific receptors (CD81, CLDN1, OCLN, and SR-BI) ENSG00000142627 ENSG00000107862 ENSG00000110048 ENSG00000285482 ENSG00000110651 ENSG00000146648 ENSG00000101558 PMC3158628__F1 Unlinking of the Golgi ribbon during G2 inhibits the recruitment and activation of Aur-A at the centrosome trough a novel mechanism ENSG00000129474 ENSG00000101224 ENSG00000166851 PMC6316730__F4 KEGG pathway analysis of the cell cycle in GNP-treated cells ENSG00000145604 ENSG00000094804 ENSG00000118007 ENSG00000101972 ENSG00000134982 ENSG00000132646 ENSG00000123374 ENSG00000205250 ENSG00000277273 ENSG00000117399 ENSG00000276876 ENSG00000093009 PMC11119800__F2 OGT is required for the development of infectious liver diseases ENSG00000147162 ENSG00000198408 ENSG00000198793 PMC11119800__F1 Involvement of OGT in hepatic cellular stress ENSG00000177169 ENSG00000147162 ENSG00000144895 ENSG00000198793 ENSG00000168404 ENSG00000285379 PMC11119800__F4 OGT has dual effects on liver fibrosis ENSG00000147162 ENSG00000160181 PMC7076893__F8 Critical pathways of the potential Alpha-glucosidase inhibitors from RS ENSG00000140992 ENSG00000171105 PMC4084917__F7 Fatostatin Displays High Anti-Tumor Activity in Prostate Cancer by Blocking SREBP-Regulated Metabolic Pathways and Androgen Receptor Signaling ENSG00000110921 ENSG00000112972 ENSG00000130164 ENSG00000113161 ENSG00000169710 ENSG00000167508 PMC11119800__F3 OGT contributes to the progression of NAFLD ENSG00000143799 ENSG00000147162 ENSG00000150907 ENSG00000100219 ENSG00000096717 ENSG00000142082 ENSG00000106305 ENSG00000026103 PMC9065265__F5 SLC7A11, a Potential Therapeutic Target Through Induced Ferroptosis in Colon Adenocarcinoma ENSG00000168003 ENSG00000138079 ENSG00000167468 ENSG00000026508 ENSG00000023909 PMC11119800__F5 Biological function of OGT in HCC ENSG00000147162 ENSG00000157227 ENSG00000198793 ENSG00000153201 ENSG00000168036 ENSG00000100985 ENSG00000172977 ENSG00000285379 PMC8827490__F1 Systems Biology Modeling of the Complement System Under Immune Susceptible Pathogens ENSG00000039537 ENSG00000009724 ENSG00000113600 ENSG00000203710 ENSG00000166278 ENSG00000132693 ENSG00000236625 PMC4473797__F6 E3 Ubiquitin Ligases Pellinos as Regulators of Pattern Recognition Receptor Signaling and Immune responses ENSG00000276561 ENSG00000164342 PMC4473797__F4 E3 Ubiquitin Ligases Pellinos as Regulators of Pattern Recognition Receptor Signaling and Immune responses ENSG00000172005 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC7019684__F2 mTORC1 is activated by amino acids, such as leucine, HMB, and arginine ENSG00000177169 ENSG00000150907 ENSG00000239282 PMC7827494__F2 Notch crosstalk with other signaling pathways ENSG00000122882 ENSG00000135547 ENSG00000281324 ENSG00000162337 ENSG00000170558 ENSG00000168036 ENSG00000164690 ENSG00000114315 ENSG00000128602 PMC12040673__F6 Structural features and signaling pathway of RLRs ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC12040673__F5 Inhibitory effects of supersulfides on the TLR signaling pathway ENSG00000162711 ENSG00000136869 PMC12075957__F11 Canagliflozin alleviates progestin resistance by suppressing RARB/CRABP2 signaling in THRB knockout endometrial cancer cells ENSG00000143320 PMC7321795__F3 Mechanisms of Selected circRNAs in CAD(A) circNfix leads to the degradation of Beta-catenin and inhibits cell proliferation through combining with miR-214 ENSG00000065978 ENSG00000134057 ENSG00000088305 ENSG00000158828 ENSG00000168036 ENSG00000145386 ENSG00000143995 ENSG00000291368 PMC8998738__F8 Dual Anti-Inflammatory and Anti-Proliferative 3-Styrylchromone Derivative Synergistically Enhances the Anti-Cancer Effects of DNA-Damaging Agents on Colon Cancer Cells by Targeting HMGB1-RAGE-ERK1/2 Signaling ENSG00000039537 ENSG00000189403 PMC3588051__F3 Ingenuity Pathway analysis of lung cancer and/or COPD versus controls revealed NFKB as a major foundation ENSG00000150991 ENSG00000092820 ENSG00000132693 PMC3057579__F9 Hypothetical diaphragm of HS7 induced apoptosis and inhibition of Wnt/Beta-catenin signaling pathway in HT-29 colon cancer cells ENSG00000137673 ENSG00000168036 ENSG00000167074 PMC5591886__F2 A crosstalk between endoplasmic reticulum (ER) stress and p38 mitogen-activated protein kinase (p38 MAPK) pathway in the context of pemphigus ENSG00000140564 PMC8922473__F6 Retinoic Acid-Induced 2 (RAI2) Is a Novel Antagonist of Wnt/Beta-Catenin Signaling Pathway and Potential Biomarker of Chemosensitivity in Colorectal Cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000175029 PMC4684888__F1 Interactions of oxidative stress, inflammation, insulin resistance, and hyperandrogenemia are described briefly in the figure, which are all involved in polycystic ovary syndrome physiopathology ENSG00000171105 ENSG00000129214 ENSG00000146678 PMC6861325__F4 Pathway analysis network of 131 preliminary potential genes ENSG00000019991 ENSG00000157404 ENSG00000145147 ENSG00000134215 ENSG00000138798 ENSG00000064300 ENSG00000010319 ENSG00000196549 ENSG00000277236 ENSG00000115353 ENSG00000151882 ENSG00000112964 ENSG00000100448 ENSG00000050628 ENSG00000109321 ENSG00000145777 ENSG00000076555 ENSG00000170381 ENSG00000117020 ENSG00000153993 ENSG00000170962 ENSG00000004948 ENSG00000137077 ENSG00000168229 ENSG00000134853 ENSG00000140285 ENSG00000126895 ENSG00000170989 ENSG00000136160 ENSG00000075213 ENSG00000113494 PMC8472484__F9 Ailanthoidol, a Neolignan, Suppresses TGFB1-Induced HepG2 Hepatoblastoma Cell Progression ENSG00000087245 ENSG00000170558 PMC7057934__F7 Schematic model of the underlying mechanisms of miR-126-3p-mediated suppression of proliferation, migration and invasion through the PI3K/PDK1/AKT pathway ENSG00000002330 ENSG00000149269 ENSG00000067900 ENSG00000124181 PMC5789953__F1 Lipoic acid synthesis and scavenging in E ENSG00000107798 ENSG00000188992 ENSG00000173239 PMC9649744__F4 New insights into the characteristics of DRAK2 and its role in apoptosis: From molecular mechanisms to clinically applied potential PMC7306856__F1 Autophagy pathway ENSG00000177169 ENSG00000183735 ENSG00000188554 ENSG00000123395 ENSG00000131238 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000157954 ENSG00000145782 ENSG00000057663 ENSG00000136874 PMC9063434__F2 Metallodrugs: an approach against invasion and metastasis in cancer treatment ENSG00000169554 ENSG00000065833 ENSG00000026103 PMC8335161__F2 Impact of lncRNAs and miRNAs on Apoptosis in Lung Cancer ENSG00000177169 ENSG00000152348 ENSG00000039537 ENSG00000113600 ENSG00000126775 ENSG00000198793 ENSG00000155792 ENSG00000167965 ENSG00000171791 ENSG00000057663 ENSG00000101407 ENSG00000188554 ENSG00000144848 ENSG00000145782 PMC8335161__F1 Impact of lncRNAs and miRNAs on Apoptosis in Lung Cancer ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000002330 ENSG00000253352 ENSG00000168040 ENSG00000135116 ENSG00000164305 ENSG00000104081 ENSG00000283100 ENSG00000115317 ENSG00000026103 PMC8335161__F3 Impact of lncRNAs and miRNAs on Apoptosis in Lung Cancer ENSG00000138795 ENSG00000281324 ENSG00000041982 ENSG00000162337 ENSG00000138798 ENSG00000124766 ENSG00000168036 ENSG00000146648 PMC6361976__F1 The largest gene regulatory subnetworks in yeast ENSG00000138433 PMC3775241__F3 Regulation of hepatic hepcidin induction at the cellular level ENSG00000137834 ENSG00000010704 ENSG00000106327 ENSG00000187045 ENSG00000168610 ENSG00000204217 ENSG00000164619 PMC5382783__F5 Screening the active compounds of Phellodendri Amurensis cortex for treating prostate cancer by high-throughput chinmedomics ENSG00000255974 ENSG00000148344 ENSG00000062485 PMC2919646__F2 Cystic Kidney Disease: the Role of Wnt Signaling ENSG00000140463 ENSG00000134086 ENSG00000100592 ENSG00000134982 ENSG00000181004 ENSG00000168036 ENSG00000167074 ENSG00000113971 ENSG00000132478 ENSG00000179941 ENSG00000174483 PMC9482125__F11 CyR61 expression and release by 3-mercaptopyruvate sulfurtransferase in colon cancer cells ENSG00000185591 ENSG00000164690 ENSG00000123268 PMC7298716__F9 DINO regulation in HPV-positive cervical cancer cells ENSG00000149311 ENSG00000124762 PMC1934518__F2 Ligands identified for EpCAM and possible functions related to them ENSG00000119888 ENSG00000010278 PMC6361976__F2 The pertinent features of the phosphocholine pathways ENSG00000163624 ENSG00000146005 ENSG00000173599 PMC4157394__F13 Apoptosis pathways affected by rocaglamides ENSG00000168040 PMC10816399__F2 IL-6R interaction with gp130 for Stat3-mediated inflammatory target gene expression ENSG00000168610 PMC4157394__F12 Inhibition of protein synthesis by rocaglamides ENSG00000198793 PMC4085993__F4 Iron Homeostasis in Peripheral Nervous System, Still a Black Box? ENSG00000197971 ENSG00000158887 PMC3408425__F9 Systems-level regulation of metabolic genes by Met TFs ENSG00000163624 ENSG00000100412 ENSG00000146701 ENSG00000128513 PMC6055003__F1 Notch pathway is regulated by short-range cell–cell signaling ENSG00000168214 ENSG00000128917 ENSG00000148400 ENSG00000074181 ENSG00000090932 PMC8549964__F3 Local delivery of FTY720 induces neutrophil activation through chemokine signaling in an oronasal fistula model ENSG00000104365 ENSG00000119535 ENSG00000125735 ENSG00000291971 ENSG00000137070 ENSG00000067900 ENSG00000116701 ENSG00000163737 ENSG00000121807 ENSG00000105639 ENSG00000273936 ENSG00000141968 ENSG00000186810 ENSG00000108691 ENSG00000141480 ENSG00000108688 ENSG00000184371 ENSG00000113263 ENSG00000135503 ENSG00000171608 ENSG00000100365 PMC5659022__F2 Proposed scheme for the role of BMSCs in modulation of p53-miRNA interaction in association with stroma-induced drug resistance in MM ENSG00000124762 PMC8549964__F2 Local delivery of FTY720 induces neutrophil activation through chemokine signaling in an oronasal fistula model ENSG00000166501 ENSG00000170989 ENSG00000180739 ENSG00000067900 ENSG00000213694 ENSG00000171791 ENSG00000125910 ENSG00000171608 ENSG00000267534 ENSG00000137841 PMC2810618__F8 Signaling network model for heart valve development and remodeling ENSG00000170961 ENSG00000065361 ENSG00000113070 ENSG00000146648 ENSG00000131196 PMC4006928__F1 DNA Damage Response, Redox Status and Hematopoiesis ENSG00000149311 ENSG00000168283 PMC3149098__F6 GProX Pathway Analysis of the Cellular Response to EGF Stimulation ENSG00000198517 ENSG00000076706 ENSG00000087842 PMC8164969__F2 Molecular pathways governing hepcidin regulation in the liver ENSG00000010704 ENSG00000106327 ENSG00000187045 ENSG00000178752 ENSG00000105697 ENSG00000164362 ENSG00000168610 ENSG00000079999 PMC8164969__F1 Iron regulatory cycle ENSG00000010704 ENSG00000106327 ENSG00000187045 ENSG00000178752 ENSG00000105697 PMC5455213__F1 Evolving Role of Diverse Gaseous Transmitters Mediating Heterocellular Communication Within the Vasculature PMC5360051__F5 Proposed deregulation of type I IFN signalling pathway by AFB1 ENSG00000105397 PMC5453167__F2 Protein-protein interaction network of the DEGs ENSG00000152034 ENSG00000114487 ENSG00000186976 ENSG00000177606 ENSG00000159352 ENSG00000179295 PMC8393694__F2 Targeting of Native Proteins to the Endoplasmic Reticulum-Associated Degradation (ERAD) Pathway: An Expanding Repertoire of Regulated Substrates ENSG00000113161 ENSG00000120437 PMC4005604__F2 Targeting the Mevalonate Cascade as a New Therapeutic Approach in Heart Disease, Cancer and Pulmonary Disease ENSG00000205221 ENSG00000070831 ENSG00000198793 ENSG00000163914 ENSG00000197429 PMC7405053__F1 An overview of PG biosynthesis, receptors, and downstream signalling pathways ENSG00000085662 PMC7405053__F3 Possible mechanisms for PGE2 modulation of immune cell functions in COVID‐19 ENSG00000162711 ENSG00000108691 ENSG00000111537 ENSG00000115415 ENSG00000130234 ENSG00000125538 ENSG00000184012 ENSG00000172936 ENSG00000168610 ENSG00000276561 PMC5206770__F10 Dual Inhibition of PI3K/Akt and mTOR by the Dietary Antioxidant, Delphinidin, Ameliorates Psoriatic Features In Vitro and in an Imiquimod-Induced Psoriasis-Like Disease in Mice ENSG00000005882 ENSG00000198793 ENSG00000163914 ENSG00000164327 PMC2832675__F1 Mathematical Modelling of Cell-Fate Decision in Response to Death Receptor Engagement ENSG00000171791 ENSG00000168040 ENSG00000064012 ENSG00000164305 PMC4259944__F1 Mutant epidermal growth factor receptor endocytic trafficking ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC7173364__F6 Apoptotic Cell Death Induced by Fractions F2 and F3 of Vitex Rotundifolia in T-47D Cell Line ENSG00000180210 ENSG00000117525 PMC9164338__F5 Exposure of human cerebral microvascular endothelial cells hCMEC/D3 to laminar shear stress induces vascular protective responses ENSG00000023909 ENSG00000124588 PMC5584748__F3 Chronic obstructive pulmonary disease candidate gene prioritization based on metabolic networks and functional information ENSG00000121207 ENSG00000108242 ENSG00000138115 ENSG00000197408 ENSG00000140505 ENSG00000255974 ENSG00000160870 ENSG00000140465 ENSG00000073737 PMC4675101__F8 Molecular pathway underlying interaction of Zn deficiency and miR-31 overexpression in promoting esophageal preneoplasia ENSG00000143546 ENSG00000163220 ENSG00000196182 ENSG00000185591 PMC533862__F1 Heuristic model showing the tyrosine phosphorylation signaling pathways in sperm cell involved in capacitation ENSG00000166278 PMC3897565__F1 Overcoming intrinsic inhibitory pathways to augment the antineoplastic activity of adoptively transferred T cells ENSG00000124181 PMC9164338__F7 Exposure of human cerebral microvascular endothelial cells hCMEC/D3 to laminar shear stress induces vascular protective responses ENSG00000105397 ENSG00000115415 ENSG00000026103 PMC5289288__F1 Identification of KRT16 as a Target of an Autoantibody Response in Complex Regional Pain Syndrome ENSG00000182718 ENSG00000206075 ENSG00000101981 ENSG00000186395 ENSG00000186847 ENSG00000001167 ENSG00000172236 ENSG00000138185 ENSG00000131095 ENSG00000107175 PMC6102400__F1 Interactions of Lactobacillus rhamnosus GG or LRY (green) with Helicobacter pylori (red) and damaged epithelial cells at the gastric mucosal surface ENSG00000138798 ENSG00000184956 PMC9336529__F2 Clinical potential of the Hippo-YAP pathway in bladder cancer ENSG00000143409 ENSG00000131023 PMC5528331__F4 MAPK signalling pathway with unstable and stable (copy number and expression) genes represented ENSG00000172680 ENSG00000149930 ENSG00000120875 ENSG00000100485 ENSG00000173327 ENSG00000136997 ENSG00000196712 ENSG00000162889 ENSG00000087095 ENSG00000254445 ENSG00000065559 ENSG00000104814 ENSG00000170458 ENSG00000143507 ENSG00000175104 ENSG00000164086 ENSG00000070831 ENSG00000105329 ENSG00000138798 ENSG00000050748 ENSG00000095015 ENSG00000166484 ENSG00000099942 ENSG00000139625 ENSG00000135341 ENSG00000164305 ENSG00000073803 ENSG00000011566 ENSG00000026103 ENSG00000132906 ENSG00000027075 ENSG00000188386 ENSG00000104365 ENSG00000157764 ENSG00000109320 ENSG00000138794 ENSG00000269335 ENSG00000132478 ENSG00000127191 ENSG00000006062 ENSG00000081189 ENSG00000120910 ENSG00000221823 ENSG00000171777 ENSG00000117020 ENSG00000128272 ENSG00000177189 ENSG00000067606 ENSG00000177606 ENSG00000188130 PMC9336529__F1 Clinical potential of the Hippo-YAP pathway in bladder cancer ENSG00000186575 ENSG00000114978 ENSG00000150457 ENSG00000131023 PMC3285584__F9 Loss of Tgif Function Causes Holoprosencephaly by Disrupting the Shh Signaling Pathway ENSG00000106571 ENSG00000156574 ENSG00000164690 ENSG00000176165 PMC9336529__F3 Clinical potential of the Hippo-YAP pathway in bladder cancer ENSG00000070831 ENSG00000143878 ENSG00000143409 PMC3713848__F9 Proposed model for the integration of primary afferent, mast cell and sympathetic systems in supporting CRPS-related nociception ENSG00000132329 ENSG00000125538 PMC4401766__F1 Simulation Predicts IGFBP2-HIF1A Interaction Drives Glioblastoma Growth ENSG00000134086 ENSG00000115457 PMC4828118__F3 Drugs interfering with breast cancer (BC)- and obesity-related pathways ENSG00000198793 PMC5544725__F7 Role of 1,25(OH)2D3 in myofibroblast differentiation and extracellular matrix deposition in TGFB1-induced nasal polyp-derived fibroblasts and nasal ex vivo organ culture PMC2840262__F2 Autophagy and the Ubiquitin-Proteasome System in Cardiac Dysfunction ENSG00000094631 ENSG00000188554 ENSG00000151929 PMC7730964__F1A Inhibition of the Wnt Signalling Pathway: An Avenue to Control Breast Cancer Aggressiveness ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4934886__F4 Aortic valve stenosis–related biological processes ENSG00000135547 ENSG00000169071 ENSG00000274736 ENSG00000041982 ENSG00000125398 ENSG00000157150 ENSG00000038427 ENSG00000155011 ENSG00000100979 ENSG00000198910 ENSG00000101160 ENSG00000100448 ENSG00000132170 ENSG00000138378 ENSG00000261371 ENSG00000138193 ENSG00000133048 ENSG00000118785 ENSG00000134013 ENSG00000145192 ENSG00000152952 ENSG00000162706 ENSG00000100234 ENSG00000125740 ENSG00000140564 ENSG00000120149 ENSG00000020633 ENSG00000112715 ENSG00000104332 ENSG00000174807 ENSG00000136859 ENSG00000104783 ENSG00000128052 ENSG00000111341 ENSG00000168398 ENSG00000179399 ENSG00000139626 ENSG00000123610 ENSG00000130208 ENSG00000137673 ENSG00000275385 ENSG00000113070 ENSG00000277641 ENSG00000198435 ENSG00000050165 ENSG00000291748 ENSG00000100985 ENSG00000141655 ENSG00000134460 ENSG00000164932 ENSG00000142798 ENSG00000168702 ENSG00000133937 ENSG00000180772 ENSG00000182985 ENSG00000138356 ENSG00000266964 ENSG00000100385 ENSG00000159216 ENSG00000198670 ENSG00000006327 ENSG00000145824 ENSG00000100558 ENSG00000087245 ENSG00000156076 ENSG00000242252 ENSG00000148400 ENSG00000164761 ENSG00000162551 ENSG00000077984 ENSG00000008394 ENSG00000007908 ENSG00000007171 ENSG00000148848 ENSG00000143387 ENSG00000151025 ENSG00000186810 ENSG00000161921 ENSG00000111799 ENSG00000124440 ENSG00000162692 ENSG00000107562 ENSG00000105329 ENSG00000163739 ENSG00000113161 ENSG00000168036 ENSG00000288488 ENSG00000029559 ENSG00000130164 ENSG00000116194 ENSG00000072657 ENSG00000196549 ENSG00000124256 ENSG00000137834 ENSG00000105639 ENSG00000167123 ENSG00000130165 ENSG00000205038 ENSG00000157766 ENSG00000163131 ENSG00000126353 ENSG00000100739 PMC8268239__F5 Footprint of Kynurenine Pathway in Neurodegeneration: Janus-Faced Role in Parkinson’s Disorder and Therapeutic Implications ENSG00000106305 PMC8837098__F1 mTOR Signaling Components in Tumor Mechanobiology PMC11963613__F4 This schematic illustrates the role of Wnt/Beta-catenin signaling in tumor immune evasion and potential therapeutic strategies targeting this pathway ENSG00000089692 ENSG00000181847 ENSG00000134982 ENSG00000168036 PMC11963613__F3 This figure illustrates the toxicity and management strategies associated with Wnt-directed therapies in cancer treatment ENSG00000134982 ENSG00000154059 ENSG00000168036 PMC8268239__F1 Footprint of Kynurenine Pathway in Neurodegeneration: Janus-Faced Role in Parkinson’s Disorder and Therapeutic Implications ENSG00000183077 ENSG00000125968 PMC11963613__F1 This figure illustrates the role of the APC gene within the Wnt signaling pathway and its significance as a cancer biomarker ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3256849__F6 A model for Kv1.3-mediated signaling pathway in human T effector memory cell differentiation ENSG00000134057 PMC6165247__F1 Consequences of endoplasmic reticulum stress response pathway ENSG00000128272 ENSG00000198793 ENSG00000100219 PMC6288292__F2 Effect of different preconditioning stimuli in the MSCs response ENSG00000178860 ENSG00000019991 ENSG00000163235 ENSG00000125538 ENSG00000121966 PMC3662029__F4 Mnk Kinases in Cytokine Signaling and Regulation of Cytokine Responses ENSG00000111537 ENSG00000187608 PMC8197724__F1 P53 up-regulated modulator of apoptosis (PUMA) in ovarian development, cardiovascular and neurodegenerative diseases ENSG00000120868 ENSG00000168040 PMC6544365__F1 PI3K/Akt signal pathway is crucial to SDF1/CXCR-mediated homing of endothelial progenitor cells (EPCs) after myocardiac infarction ENSG00000162692 ENSG00000121966 PMC10088895__F1 PD-1/PD-L1 pathway plays a role in immunosuppression ENSG00000291603 ENSG00000213658 ENSG00000134982 PMC4498277__F2 Sclerostin actions ENSG00000152266 ENSG00000281324 ENSG00000162337 ENSG00000134569 PMC3137161__F1 Roles of shati on dopamine uptake – the relationship shati and TNFA ENSG00000075142 PMC5644649__F3 Signaling model of Nef-mediated (A) apoptosis/anti-apoptosis, (B) down-regulation of expression of MHC class I molecules, and (C) down-regulation of the expression of CD4 molecules ENSG00000002330 ENSG00000070831 ENSG00000143761 ENSG00000175115 ENSG00000165527 PMC4599194__F1 Schematic model of MIF pathways in breast cancer cells (BCC) ENSG00000019582 ENSG00000121966 PMC8231548__F3 Perivascular Adipose Tissue-Derived Adiponectin in Vascular Homeostasis ENSG00000157500 ENSG00000169047 ENSG00000102104 PMC9010822__F1 Molecular Mechanisms Involving the Sonic Hedgehog Pathway in Lung Cancer Therapy: Recent Advances ENSG00000136997 ENSG00000164690 PMC11615816__F6 PGRN Inhibits B‐cell Activation and IgE Production through the PGRN‐IFITM3‐STAT1 Signaling Pathway ENSG00000177455 ENSG00000030582 ENSG00000185201 PMC9010822__F6 Molecular Mechanisms Involving the Sonic Hedgehog Pathway in Lung Cancer Therapy: Recent Advances ENSG00000119977 ENSG00000175793 ENSG00000198793 ENSG00000026508 ENSG00000164690 ENSG00000171791 ENSG00000128602 ENSG00000118777 PMC9010822__F3 Molecular Mechanisms Involving the Sonic Hedgehog Pathway in Lung Cancer Therapy: Recent Advances ENSG00000172005 ENSG00000121879 PMC9010822__F2 Molecular Mechanisms Involving the Sonic Hedgehog Pathway in Lung Cancer Therapy: Recent Advances ENSG00000256762 ENSG00000164690 ENSG00000128602 PMC9010822__F5 Molecular Mechanisms Involving the Sonic Hedgehog Pathway in Lung Cancer Therapy: Recent Advances ENSG00000154309 ENSG00000164690 ENSG00000128602 PMC9010822__F4 Molecular Mechanisms Involving the Sonic Hedgehog Pathway in Lung Cancer Therapy: Recent Advances ENSG00000119977 ENSG00000141448 ENSG00000117425 ENSG00000163818 ENSG00000164161 ENSG00000179029 ENSG00000103145 ENSG00000154309 ENSG00000164690 ENSG00000128602 ENSG00000104723 PMC2955614__F5 Novel molecular regulation of Wnt/Beta-catenin pathway ENSG00000169554 ENSG00000171720 ENSG00000134982 ENSG00000151650 ENSG00000168036 ENSG00000154310 ENSG00000196470 ENSG00000168505 ENSG00000168610 ENSG00000146648 ENSG00000136826 PMC8476931__F5 Chromosome-level genome assembly of Gynostemma pentaphyllum provides insights into gypenoside biosynthesis ENSG00000105722 ENSG00000197429 ENSG00000169727 PMC7838037__F5 NF-Kß mediated signaling pathway leading to mucus hypersecretion ENSG00000138798 ENSG00000185591 ENSG00000146648 ENSG00000293532 PMC7838037__F4 MAPK mediated signaling pathway induced by interleukins leading to mucus hypersecretion ENSG00000291363 ENSG00000172936 ENSG00000117983 ENSG00000145113 ENSG00000293532 PMC4488716__F1 Signaling pathways of the endoplasmic reticulum (ER) stress response ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC4517435__F1 Core components of the insulin signaling pathway ENSG00000104812 ENSG00000140992 ENSG00000117020 ENSG00000129946 ENSG00000169047 ENSG00000111713 ENSG00000115904 ENSG00000169032 ENSG00000100485 ENSG00000196396 ENSG00000160691 PMC8832963__F3 Emerging role of long noncoding RNA RMRP in cancer development and targeted therapy ENSG00000182718 ENSG00000131876 ENSG00000118971 PMC9559463__F3 Long-Term Management of Advanced Basal Cell Carcinoma: Current Challenges and Future Perspectives ENSG00000128602 PMC9559463__F5 Long-Term Management of Advanced Basal Cell Carcinoma: Current Challenges and Future Perspectives ENSG00000089692 ENSG00000111537 ENSG00000134982 ENSG00000128602 PMC7926472__F1 A general map of core metabolism ENSG00000182511 ENSG00000166278 PMC3392647__F3 Metabolic regulation of epigenetics ENSG00000147162 ENSG00000077463 ENSG00000096717 PMC3875828__F1 Asp and aromatic amino acid biosynthetic pathways in plants ENSG00000108849 ENSG00000110395 ENSG00000166183 PMC7350257__F2 PI3K-AKT-mTOR and RAS/MAPK pathway crosstalk can contribute to mTORC1 and AKT inhibitor resistance ENSG00000177169 ENSG00000002330 ENSG00000169047 ENSG00000118515 PMC7019732__F6 FIPV nsp5-mediated inhibition of the type I IFN signaling pathway during FIPV infection ENSG00000183735 ENSG00000088888 ENSG00000082512 ENSG00000175104 ENSG00000127191 PMC7350257__F4 PI3K-AKT-mTOR and WNT signaling crosstalk ENSG00000101407 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000135446 ENSG00000136997 ENSG00000155792 ENSG00000124766 ENSG00000168036 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC7350257__F3 PI3K-AKT-mTOR and AR signaling crosstalk facilitates resistance to androgen/AR and AKT-directed monotherapy PMC9559463__F1 Long-Term Management of Advanced Basal Cell Carcinoma: Current Challenges and Future Perspectives ENSG00000128602 PMC11302957__F1 Core components of the Hippo pathway in mammals ENSG00000167601 ENSG00000109321 ENSG00000131023 PMC11302957__F3 Crosstalk of Hippo signal pathway with other signaling pathways to regulate YAP1 ENSG00000135437 ENSG00000019991 ENSG00000198793 ENSG00000114209 ENSG00000146648 ENSG00000100625 ENSG00000131023 PMC4868686__F6 VE-cadherin cleavage by ovarian cancer microparticles induces Beta-catenin phosphorylation in endothelial cells ENSG00000087245 ENSG00000138795 ENSG00000137673 ENSG00000162337 ENSG00000134982 ENSG00000149269 ENSG00000168036 ENSG00000100985 PMC6998390__F8 BACE2‐regulated pathway in glioma cells ENSG00000182240 PMC4521049__F8 New working model ENSG00000136869 ENSG00000105246 ENSG00000162692 PMC428488__F1 Outline of the Taxol biosynthetic pathway ENSG00000113600 ENSG00000197429 PMC2992289__F5 KLA increases mRNA expression of genes involved in sphingolipid biosynthesis ENSG00000100422 ENSG00000063176 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000188611 ENSG00000143418 ENSG00000135587 PMC3073335__F2 RNA helicases of the RIG-I-like receptor (RLR) family play a crucial role in the innate antiviral response ENSG00000213928 ENSG00000276561 PMC10846991__F3 Interleukin-6 (IL-6) signaling pathway ENSG00000129946 ENSG00000198793 ENSG00000168610 PMC7367493__F2 RNA sensing and regulatory roles of NLRs ENSG00000278718 ENSG00000162711 ENSG00000167207 ENSG00000109606 ENSG00000174885 ENSG00000057663 ENSG00000101695 ENSG00000088888 ENSG00000125538 ENSG00000160703 ENSG00000158077 ENSG00000142405 ENSG00000185792 ENSG00000145782 ENSG00000121060 PMC7367493__F1 TLR and RLR signaling pathways ENSG00000137275 ENSG00000141569 ENSG00000276561 ENSG00000142166 ENSG00000183735 ENSG00000088888 ENSG00000134070 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000247315 ENSG00000121060 ENSG00000184216 ENSG00000164342 PMC10846991__F4 Overall signaling pathways between podocytes and glomerular endothelial cells (GECs) ENSG00000107562 ENSG00000091879 ENSG00000112715 ENSG00000154188 ENSG00000121966 PMC11799769__F4 Correlation network diagram between renal‐secreted proteins and proteins on the most significantly altered KEGG pathways in skeletal muscle ENSG00000162377 ENSG00000130702 ENSG00000107902 ENSG00000163541 ENSG00000173402 ENSG00000229314 ENSG00000172037 ENSG00000165264 ENSG00000178127 ENSG00000267855 ENSG00000118785 ENSG00000128609 ENSG00000188130 ENSG00000128342 ENSG00000146701 PMC5635761__F1 Possible Nucleic acid sensors participation in HBV pattern sensing in the life cycle of HBV ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000163568 ENSG00000163565 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC7790818__F3 Prostate apoptosis response-4 and tumor suppression: it’s not just about apoptosis anymore ENSG00000171791 ENSG00000026103 PMC7047768__F1 Summary of transcriptional regulation of senescence in MSCs ENSG00000188486 ENSG00000178860 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC11232665__F4 Metformin likely acts on intervertebral disc degeneration through SIRT-related signalling pathways ENSG00000158828 ENSG00000096717 ENSG00000142082 PMC3789782__F1 Herpes Simplex Virus Type 1 Single Strand DNA Binding Protein and Helicase/Primase Complex Disable Cellular ATR Signaling ENSG00000175054 ENSG00000164053 ENSG00000276618 PMC11232665__F3 Mechanism of metformin in intervertebral disc degeneration ENSG00000178860 ENSG00000164430 ENSG00000189403 ENSG00000099940 PMC6438438__F8 Diagram demonstrating the unfolded protein response pathway and downstream chaperone proteins ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC11232665__F2 Intervertebral disc degeneration ENSG00000149968 ENSG00000169047 ENSG00000198793 ENSG00000162772 ENSG00000142082 PMC6711852__F2 Physiological and pathological hypertrophy ENSG00000179862 ENSG00000285109 ENSG00000198793 ENSG00000064655 PMC10189743__F5 Involvement of ITGA and ITGB receptors in ‘focal adhesion’ and ‘ECM receptor interaction’ from the Kyoto Encyclopaedia of Genes and Genomes pathway database ENSG00000169291 ENSG00000002330 ENSG00000070831 PMC6181582__F3 Protein based pathway mapping of the patient response in the serum to antibiotic treatment ENSG00000113905 ENSG00000100979 ENSG00000173083 ENSG00000158874 ENSG00000115718 ENSG00000166211 ENSG00000127948 PMC3163839__F3 Progression of amyloidogenesis in parahippocampal region and hippocampal formation of mediotemporal lobe ENSG00000164879 ENSG00000096717 PMC3163839__F2 Sirt1 activity as it relates to AD etiology ENSG00000096717 ENSG00000137845 PMC3697894__F1 Notch signaling pathway ENSG00000128917 ENSG00000138798 ENSG00000205155 ENSG00000090932 PMC8353789__F1 Perspective on therapies for amyotrophic lateral sclerosis: can disease progression be curbed? ENSG00000094631 ENSG00000123395 ENSG00000126775 ENSG00000198793 ENSG00000112561 PMC12170998__F2 Development of Traditional Chinese Medicine in combination with EGFR Inhibitors against Cancer ENSG00000198793 ENSG00000146648 PMC12170998__F3 Molecular pathways related to EGFR-TKI resistance ENSG00000167601 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC7074480__F1 Mechanism of action of the nucleotide-binding oligomerization domain-like receptor (NLR) family pyrin domain containing 3 (NLRP3) inflammasome ENSG00000278718 ENSG00000162711 PMC8631411__F2 Molecular mechanism and therapeutic targeting of necrosis, apoptosis, pyroptosis, and autophagy in cardiovascular disease ENSG00000278718 ENSG00000162711 ENSG00000163568 PMC8631411__F1 Molecular mechanism and therapeutic targeting of necrosis, apoptosis, pyroptosis, and autophagy in cardiovascular disease ENSG00000110497 ENSG00000198382 ENSG00000102871 ENSG00000166278 ENSG00000168040 ENSG00000127191 ENSG00000145782 PMC4037387__F2 JAK/STAT pathway dysregulation in tumors: A Drosophila perspective ENSG00000198901 PMC3203219__F1 Costimulatory pathways relevant in transplantation ENSG00000134982 PMC4180975__F8 Model depicting CtsZ regulation of the protumorigenic functions of TAMs and cancer cells ENSG00000101160 ENSG00000291971 PMC4060956__F1 Abnormal Ca2+signaling in SNc DA neurons may cause mitochondrial oxidant stress, proteostasis deficits and eventual cell death ENSG00000196531 ENSG00000158828 PMC10376991__F8 An Autophagy-Associated MITF–GAS5–miR-23 Loop Attenuates Vascular Oxidative and Inflammatory Damage in Sepsis ENSG00000079999 PMC3359066__F5 Identification of Functional Differences in Metabolic Networks Using Comparative Genomics and Constraint-Based Models ENSG00000172005 ENSG00000082212 PMC7465596__F1 Signaling and gene regulation of the canonical cell autonomous unfolded protein response (UPR) ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC6682706__F1 Natural plant compounds and epithelial-to-mesenchymal transition ENSG00000019991 ENSG00000170365 ENSG00000111859 ENSG00000105329 ENSG00000149968 ENSG00000170558 ENSG00000198793 ENSG00000168036 ENSG00000198670 ENSG00000168610 PMC12142240__F7 Proposed pathway by which reduced SPDL1 expression leads to epithelial-mesenchymal transition and promotes cell migration and invasion in colorectal cancer ENSG00000138798 ENSG00000040275 ENSG00000146648 PMC11562816__F1 Low-frequency variants in genes involved in glutamic acid metabolism and Gamma-glutamyl cycle and risk of coronary artery disease in type 2 diabetes ENSG00000125166 ENSG00000178814 ENSG00000167261 ENSG00000059573 ENSG00000023909 ENSG00000115419 PMC4160336__F4 Bacterial factors exploit eukaryotic Rho GTPase signaling cascades to promote invasion and proliferation within their host ENSG00000070831 ENSG00000163914 ENSG00000106100 PMC4647833__F3 Investigation of Pathogenic Genes in Chinese sporadic Hypertrophic Cardiomyopathy Patients by Whole Exome Sequencing ENSG00000138347 ENSG00000143549 ENSG00000075142 ENSG00000118729 ENSG00000077522 ENSG00000198626 ENSG00000101306 ENSG00000114686 ENSG00000106617 ENSG00000101605 ENSG00000137364 ENSG00000005893 ENSG00000160808 ENSG00000172399 ENSG00000155657 ENSG00000164916 ENSG00000026103 ENSG00000101608 ENSG00000155090 PMC10844198__F2 Putative NFKB signaling pathway data mined from Euprymna scolopes reference transcriptome and genome ENSG00000183735 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000076604 PMC4041713__F4 Differential Expression of MicroRNA and Predicted Targets in Pulmonary Sarcoidosis ENSG00000163637 ENSG00000087095 ENSG00000166167 ENSG00000221914 ENSG00000134982 ENSG00000173218 ENSG00000183943 ENSG00000168036 ENSG00000196470 ENSG00000155760 ENSG00000101333 ENSG00000168772 PMC4041713__F2 Differential Expression of MicroRNA and Predicted Targets in Pulmonary Sarcoidosis ENSG00000107779 ENSG00000103479 ENSG00000039319 ENSG00000111537 ENSG00000143768 ENSG00000198742 ENSG00000133740 ENSG00000185591 ENSG00000204217 ENSG00000137801 PMC4044302__F1 Sites of thyroid hormone regulation of metabolism ENSG00000130164 ENSG00000167910 ENSG00000170893 ENSG00000182759 ENSG00000168610 ENSG00000026103 PMC4290816__F1 Primary points at which PUFA-based supplements enter the PUFA biosynthetic pathway ENSG00000134824 ENSG00000197977 PMC3641131__F6 Novel Insulin Sensitizer Modulates Nutrient Sensing Pathways and Maintains Beta-Cell Phenotype in Human Islets ENSG00000143158 ENSG00000169047 ENSG00000198793 ENSG00000168036 ENSG00000060762 PMC7069221__F1 Estrogen biosynthesis and signaling pathways ENSG00000140465 PMC7990371__F3 Directly and indirectly anti-cancer pathways of APN ENSG00000156076 ENSG00000036672 ENSG00000198793 ENSG00000168036 ENSG00000168610 ENSG00000105723 PMC9314982__F3 Coagulation by tissue factor pathway inhibitor: Implications for hemophilia therapy PMC7069588__F4 Schematic diagram ENSG00000170558 PMC5913878__F2 Emerging roles of epithelial-mesenchymal transition in hematological malignancies ENSG00000122691 ENSG00000288335 ENSG00000168036 PMC152295__F1 The PI metabolic pathway and wortmannin sensitivity ENSG00000124102 ENSG00000197429 PMC8256442__F4 Signaling Pathways That Regulate the Crustacean Molting Gland ENSG00000171105 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8038686__F3 Tissue fragmentation and mechanical manipulation disrupt ovarian Hippo signaling pathway and promote follicle growth ENSG00000150457 ENSG00000131023 PMC120783__F7 GPI biosynthetic pathways in T ENSG00000069482 ENSG00000122194 PMC4334750__F6 Theoretical model for metabolism of alcohol in the brain ENSG00000144596 ENSG00000178719 ENSG00000166123 PMC3523810__F7 Possible inflammatory signaling pathway that results from the functional associations of the identified inflammation-related proteins (marked with an underline), which is regulated by acupuncture in asthma ENSG00000143546 ENSG00000163220 ENSG00000163914 PMC9170579__F6 Long noncoding RNAs (lncRNAs) in human lymphomas ENSG00000157554 ENSG00000074266 ENSG00000178691 PMC8783605__F3 Peripheral nerve stimulation and immunity: the expanding opportunities for providing mechanistic insight and therapeutic intervention ENSG00000125538 PMC9600404__F3 Newest Therapies for Cholangiocarcinoma: An Updated Overview of Approved Treatments with Transplant Oncology Vision ENSG00000066468 ENSG00000198793 PMC6030085__F7 SOX17-mediated disruption of Wnt/beta-catenin signaling ENSG00000164736 ENSG00000168036 PMC3346964__F1 Four major molecular pathways activated by tyrosine kinase receptor B (TrkB) and IGF-1 receptor (IGF-1R) ENSG00000198793 ENSG00000140443 PMC5071175__F4 Planar cell polarity (PCP) proteins and spermatogenesis ENSG00000169071 ENSG00000070831 ENSG00000100592 PMC9189173__F7 Study on plasma amino acids and piperonamide as potential diagnostic biomarkers of non-small cell lung cancer ENSG00000135069 PMC3918721__F1 TGFB signaling and MMPs interplay ENSG00000169291 ENSG00000163914 PMC4260876__F7 Drought Tolerance Conferred to Sugarcane by Association with Gluconacetobacter diazotrophicus: A Transcriptomic View of Hormone Pathways ENSG00000105722 ENSG00000221818 PMC6834079__F1 The Hedgehog signaling pathway and depiction of key regulatory interfaces ENSG00000164161 ENSG00000144857 ENSG00000166813 ENSG00000128602 PMC7314846__F3 N6-methyladenosine (m6A) methylation in ischemia–reperfusion injury ENSG00000128342 ENSG00000168040 ENSG00000168610 ENSG00000124762 PMC11656820__F2 Expression of Tim-3 on various immune cells and the functional alteration of these cells in sepsis-induced immunosuppression ENSG00000026508 ENSG00000189403 ENSG00000049768 PMC3124359__F1 Estrogenic effects on gp130 signaling ENSG00000099985 ENSG00000128342 ENSG00000168610 PMC11656820__F1 Tim-3 signaling pathway ENSG00000291603 ENSG00000010810 ENSG00000189403 PMC11656820__F3 Function of dysregulated Tim-3 pathway in sepsis-induced immunosuppression ENSG00000164136 ENSG00000113520 ENSG00000049768 PMC3936888__F7 Scheme for illustrating the effect of Naproxen on the regulation of cell cycle and apoptosis mediated through the inhibition of the PI3-K signaling pathway ENSG00000135446 ENSG00000198793 ENSG00000171791 PMC3033145__F2 Anticoagulant properties of endothelial cells ENSG00000003436 ENSG00000134982 ENSG00000173599 PMC9541200__F2 NAD+ deficiency in human congenital malformations and miscarriage: A new model of pleiotropy ENSG00000143799 ENSG00000105835 ENSG00000262635 ENSG00000172890 ENSG00000278488 ENSG00000291803 ENSG00000077463 ENSG00000142082 ENSG00000077009 ENSG00000291814 ENSG00000157064 ENSG00000124523 ENSG00000173614 ENSG00000089163 ENSG00000187531 ENSG00000109743 ENSG00000162882 ENSG00000183077 ENSG00000111339 ENSG00000137817 ENSG00000283100 ENSG00000156219 ENSG00000102699 ENSG00000041880 ENSG00000149743 ENSG00000096717 ENSG00000106733 PMC4568949__F5 Non-invasive prognostic protein biomarker signatures associated with colorectal cancer ENSG00000224320 ENSG00000011028 ENSG00000000971 ENSG00000182985 ENSG00000198734 ENSG00000162896 PMC7993397__F1 Integration of mechanical- and ECM-based tumor microenvironment-imposed signals ENSG00000154864 ENSG00000126016 ENSG00000186575 ENSG00000010810 ENSG00000026508 ENSG00000150457 ENSG00000131023 PMC3128083__F9 RIG-I Mediates Innate Immune Response in Mouse Neurons Following Japanese Encephalitis Virus Infection ENSG00000107201 ENSG00000168040 ENSG00000175104 ENSG00000127191 PMC9170579__F5 Long noncoding RNAs (lncRNAs) in human lymphomas ENSG00000157764 ENSG00000134982 ENSG00000135446 ENSG00000198793 ENSG00000168036 ENSG00000123374 ENSG00000105810 ENSG00000168040 PMC4687703__F2 Local inhibition of miR‐24 in ECs would turn off apoptosis signalling pathway and improves reparative angiogenesis in post‐ischaemic conditions ENSG00000164283 ENSG00000096717 ENSG00000130669 ENSG00000026103 PMC6266414__F3 Glutamine inter-tissue metabolic flux starting in skeletal muscle, liver, and gut continues in the immune cells ENSG00000173599 ENSG00000096717 ENSG00000115419 PMC4619950__F3 Main molecular pathways activated for the production of inflammatory cytokines ENSG00000019991 ENSG00000115415 ENSG00000168610 PMC6352376__F4 Functional analysis of significantly changed proteins (SCPs) ENSG00000197747 ENSG00000166340 ENSG00000100997 ENSG00000070915 ENSG00000197043 ENSG00000151726 ENSG00000088682 ENSG00000138772 ENSG00000130414 ENSG00000111271 ENSG00000100033 ENSG00000166136 ENSG00000139180 ENSG00000005893 ENSG00000075239 ENSG00000163956 ENSG00000169344 ENSG00000100345 ENSG00000177954 ENSG00000292058 ENSG00000257335 ENSG00000136731 ENSG00000178127 ENSG00000058262 ENSG00000213619 ENSG00000117480 ENSG00000151366 ENSG00000189043 ENSG00000166224 ENSG00000127824 ENSG00000276838 ENSG00000182446 ENSG00000134109 ENSG00000131495 ENSG00000109606 ENSG00000122194 ENSG00000117054 ENSG00000128609 ENSG00000196549 ENSG00000130402 ENSG00000171560 ENSG00000003056 ENSG00000155008 ENSG00000105953 ENSG00000134871 ENSG00000112874 ENSG00000114573 ENSG00000291420 ENSG00000184840 ENSG00000115875 ENSG00000166589 ENSG00000117601 ENSG00000145321 ENSG00000167996 ENSG00000072110 ENSG00000151239 ENSG00000092841 ENSG00000099795 ENSG00000129128 ENSG00000106554 ENSG00000126838 ENSG00000169994 ENSG00000164983 ENSG00000041357 ENSG00000132341 ENSG00000101608 PMC3319470__F1 Coenzyme Q10biosynthetic pathway and electron transport role in the mitochondrial respiratory chain ENSG00000132423 ENSG00000167113 ENSG00000119723 ENSG00000110871 ENSG00000171503 ENSG00000088682 ENSG00000148459 ENSG00000167186 PMC4619950__F4 Molecular pathways activated by inflammatory cytokines and growth factors and affected by MPN-associated mutations ENSG00000115415 ENSG00000117400 ENSG00000168610 PMC9189280__F7 Curcumin Blocks High Glucose-Induced Podocyte Injury via RIPK3-Dependent Pathway ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC6058053__F3 Altered B cell receptor (BCR) and co-receptor signaling promotes increased autoreactivity within the naive B cell repertoire ENSG00000186716 ENSG00000015285 PMC7124275__F9 MAPK7-CEBPB signaling cascade negative regulation of mir128-3p under ischemia/hypoxic condition ENSG00000169047 ENSG00000166484 PMC6558065__F1 Proposed MFG-E8 signaling in radial glial cells (RGL) via AvB3/PI3K/Akt/mTOR pathway ENSG00000198793 ENSG00000118971 PMC3037521__F2 Selective elimination of messenger RNA underlies the mitosis–meiosis switch in fission yeast ENSG00000179094 PMC6156430__F2 Schematic diagram of the molecular mechanisms underlying K63‐linked polyubiquitination and cardiac hypertrophy ENSG00000102871 ENSG00000157625 ENSG00000175104 ENSG00000127191 PMC7201019__F5 Pathways of viral sensing and TLR signaling, metabolism, cell motility and protein export are enriched in the NK RMtsig ENSG00000042832 ENSG00000126088 ENSG00000198793 ENSG00000173039 ENSG00000188690 ENSG00000292155 ENSG00000105402 ENSG00000169919 ENSG00000173992 ENSG00000156110 ENSG00000157766 ENSG00000127415 ENSG00000173599 ENSG00000177606 ENSG00000163131 ENSG00000122705 ENSG00000146701 PMC3587307__F1 LEM2 is a negative regulator of ERK signaling during muscle differentiation ENSG00000138798 ENSG00000198793 ENSG00000168036 PMC4890029__F9 MicroRNA-449a enhances radiosensitivity by downregulation of c-Myc in prostate cancer cells ENSG00000134057 PMC4818947__F7 Contributions of DNA repair and damage response pathways to the non-linear genotoxic responses of alkylating agents ENSG00000149311 ENSG00000175054 ENSG00000170430 PMC6765066__F13 HMGB1, a Nuclear Damage-Associated Molecular Pattern Molecule, in the Pathogenesis of Lung Diseases ENSG00000239732 ENSG00000125538 ENSG00000189403 ENSG00000169429 ENSG00000136869 ENSG00000100985 ENSG00000005381 ENSG00000096717 PMC9221142__F2 Extracellular Matrix Stiffening: A Trigger of Prostate Cancer Progression and Castration Resistance? ENSG00000291971 ENSG00000197386 ENSG00000168036 ENSG00000146648 PMC6765066__F12 HMGB1, a Nuclear Damage-Associated Molecular Pattern Molecule, in the Pathogenesis of Lung Diseases ENSG00000189403 ENSG00000169429 ENSG00000136869 ENSG00000100985 ENSG00000005381 PMC2629979__F1 Molecular Mechanisms in COPD pathogenesis and potential therapeutic targets ENSG00000105329 ENSG00000079999 PMC8586819__F2 T-cell dysfunction in chronic lymphocytic leukemia from an epigenetic perspective ENSG00000111537 ENSG00000181847 ENSG00000122223 ENSG00000163599 ENSG00000198846 PMC4495583__F3 Dendritic cell metabolism ENSG00000174125 ENSG00000162711 ENSG00000183735 ENSG00000088888 ENSG00000125538 ENSG00000136869 ENSG00000130159 ENSG00000175104 ENSG00000276561 PMC12058309__F1 Biosynthesis, metabolism and signaling of SA ENSG00000100473 ENSG00000281857 PMC4495583__F2 Dendritic cell metabolism ENSG00000183735 ENSG00000100219 ENSG00000159399 PMC5460804__F7 Schematic drawing that illustrates the likely signaling pathway by which laminin A2 at the basement membrane regulates Sertoli cell BTB dynamics in the seminiferous epithelium of rat testes PMC4937469__F11 Surviving problems during chromosome replication ENSG00000132646 ENSG00000070950 ENSG00000051180 PMC8166896__F1 Molecular mechanism of necroptosis ENSG00000124256 ENSG00000147162 ENSG00000137275 ENSG00000102871 ENSG00000105401 ENSG00000087586 ENSG00000168040 ENSG00000154124 ENSG00000127191 ENSG00000197530 ENSG00000138032 ENSG00000083799 ENSG00000168404 ENSG00000285379 ENSG00000164342 PMC8130833__F1 Targeting DNA Damage Repair Pathways in Pancreatic Adenocarcinoma ENSG00000149311 ENSG00000175054 PMC6544733__F5 Bioenergetic metabolites differ significantly between the Boxers and Chihuahuas ENSG00000039537 ENSG00000166278 PMC3458056__F5 Molecular Characteristics and Metastasis Predictor Genes of Triple-Negative Breast Cancer: A Clinical Study of Triple-Negative Breast Carcinomas ENSG00000282905 ENSG00000136997 ENSG00000164362 ENSG00000173039 ENSG00000122565 ENSG00000115461 PMC3695482__F2 Focus on Histone variant H2AX: to be or not to be ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000083093 ENSG00000139618 PMC11884491__F7 Schematic illustrates the antiproliferative effect of P ENSG00000132646 PMC8000126__F7 TR-dependent regulation of genes in the Wnt signaling pathway, a representative pathway likely involved in the development of adult intestinal stem cells, as revealed by RNA-seq analysis ENSG00000087095 ENSG00000100592 ENSG00000095739 ENSG00000100387 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000196470 ENSG00000185269 PMC5446740__F5 Disease module predicted by GLADIATOR for hyperinsulinism ENSG00000111229 ENSG00000245848 ENSG00000171105 ENSG00000179344 ENSG00000175745 ENSG00000139515 ENSG00000163453 ENSG00000185591 ENSG00000166851 ENSG00000139687 ENSG00000159202 PMC12219554__F1 Schematic illustration ENSG00000167941 ENSG00000168610 PMC7043073__F3 Impact of co-mutations on the microenvironment of KRAS-mutant lung adenocarcinoma ENSG00000136997 ENSG00000079999 PMC4991528__F3 Recommended decision pathway for UK patients considered for treatment with tolvaptan according to Renal Association guidance based on the NICE decision ENSG00000146648 PMC3706840__F8 PRL-Dependent Tyrosyl Phosphorylated PAK1 and 3D Collagen IV Regulate MMP-1 and MMP-3 Production and Invasion via MAPK Pathways Schematic representation of the proposed working model ENSG00000087245 ENSG00000149968 ENSG00000149269 PMC9418002__F2 BCL-2 family proteins ENSG00000002330 ENSG00000140379 ENSG00000186716 ENSG00000113520 ENSG00000172936 ENSG00000171791 ENSG00000184481 ENSG00000010671 ENSG00000104081 ENSG00000121966 PMC3725503__F1 Network of the mechanistic Target of Rapamycin (mTOR) signaling pathway ENSG00000127528 ENSG00000102104 PMC5145311__F2 NLRP3, NLRC5, NLRP7, AIM2 and other inflammasome-like signaling is activated in response to S ENSG00000162711 ENSG00000226275 ENSG00000163568 ENSG00000274571 PMC3001303__F1 mTOR signalling pathway ENSG00000169047 ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC7033713__F2 Summary of the effects of FGF19 signaling in specific cell types PMC5869511__F1 Antiviral innate immune pathways in dipteran insects ENSG00000172936 ENSG00000114127 ENSG00000123908 PMC3006043__F3 Colorectal Cancer Molecular Biology Moves Into Clinical Practice ENSG00000157764 ENSG00000121879 ENSG00000146648 PMC9237101__F7 Model depicts the role of the IDO1-MDM2-p53 pathway in DLBCL growth PMC7565746__F4 Diagrammatic representation of significantly differentially expressed genes associated with the fatty acid biosynthesis pathways, glycolysis, pentose phosphate pathway and TCA cycle when Schizochytrium was cultured under low-temperature conditions ENSG00000173599 ENSG00000026103 PMC6090926__F1 Molecular interactions between LRRK2, aSyn and p38 MAPK in the regulation of apoptosis and autophagy ENSG00000070831 ENSG00000198793 PMC4277436__F1 IL-33/ST2 pathway: therapeutic target and novel biomarker ENSG00000137033 ENSG00000172005 ENSG00000172936 ENSG00000175104 PMC4682238__F1 Schematic representation of Slit-Robo signaling pathway in gastric tumorigenesisᅟ ENSG00000145147 ENSG00000196935 ENSG00000198793 ENSG00000168036 PMC8820467__F2 Canonical Wnt/Beta-Catenin Pathway in Regulating Chondrocytic Hypertrophy in Mesenchymal Stem Cell-Based Cartilage Tissue Engineering ENSG00000170365 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000104885 ENSG00000020633 ENSG00000168036 ENSG00000128602 ENSG00000163501 PMC3427704__F1 AID-associated gene network ENSG00000178860 ENSG00000171311 ENSG00000100811 ENSG00000120699 ENSG00000140968 ENSG00000083520 ENSG00000114030 ENSG00000077348 ENSG00000178896 ENSG00000124391 ENSG00000107371 ENSG00000102245 ENSG00000196235 ENSG00000137265 ENSG00000196092 ENSG00000253729 ENSG00000223496 PMC3645661__F1 An overview of signaling by the EGF family (with EGF and EGFR/ErbB1 as example) from cell surface down to the nucleus (without taking into account endocytic trafficking and recycling of the receptor) ENSG00000110395 ENSG00000144749 ENSG00000138798 ENSG00000198793 ENSG00000180008 ENSG00000146648 PMC4633896__F6 Mechanistic model for irradiation-dependent and GSK3Beta-related signaling in HNSCC cells: Activated and inactivated molecules are displayed in green and in red, respectively ENSG00000198793 ENSG00000168036 ENSG00000164327 PMC355855__F10 Models for repression of TGFB signaling by the Smurf-Smad7 complex and reactivation of TGFB signaling by the Jab1/CSN5-Smad7 complex ENSG00000198742 PMC4779708__F1 Schematic model of signaling pathways implicated in tumor cell vascular mimicry (VM) ENSG00000142627 ENSG00000122691 ENSG00000291971 ENSG00000157227 ENSG00000156574 ENSG00000026508 PMC7232496__F7 Postulated mechanism of disease resistance in cattle to PPRV—Schematic representation of roles of differentially expressed genes ENSG00000213928 ENSG00000187608 ENSG00000185745 ENSG00000174840 ENSG00000276561 ENSG00000164342 PMC4425062__F6 Theoretical model of the negative regulation of the PA signal pathway by myostatin in skeletal muscle ENSG00000198793 ENSG00000115556 PMC7559280__F3 Epigenetic modifications in the livers of male young adult IUGR-N mice ENSG00000067141 ENSG00000214944 ENSG00000113763 ENSG00000033327 ENSG00000140564 ENSG00000143786 ENSG00000221866 ENSG00000181788 ENSG00000162337 ENSG00000165030 ENSG00000167680 ENSG00000176533 ENSG00000061676 ENSG00000179456 ENSG00000163631 ENSG00000117713 ENSG00000154917 ENSG00000101981 ENSG00000122691 ENSG00000183579 ENSG00000088247 ENSG00000111186 ENSG00000139372 ENSG00000135503 ENSG00000139687 ENSG00000072201 ENSG00000114450 ENSG00000146281 ENSG00000197081 ENSG00000198833 ENSG00000138411 ENSG00000065559 ENSG00000150457 ENSG00000170035 ENSG00000061938 ENSG00000116641 ENSG00000071564 ENSG00000281766 ENSG00000186716 ENSG00000070770 ENSG00000198815 ENSG00000104290 ENSG00000139154 ENSG00000124253 ENSG00000136872 ENSG00000042088 ENSG00000142279 ENSG00000130726 PMC11983340__F1 Engineered metabolic pathway for the biosynthesis of disubstituted MAAs ENSG00000179091 PMC3676795__F2 Signaling cascades that regulate the intrinsic and extrinsic pathways of apoptosis ENSG00000002330 ENSG00000168040 PMC6338478__F8 IGF-IR is now considered a functional RTK/GPCR hybrid, integrating canonical tyrosine kinase and GPCR signaling ENSG00000169047 ENSG00000133124 PMC2593006__F3 Signalling pathways underlying neuronal survival and cognitive performance ENSG00000198793 ENSG00000198576 PMC10377641__F3 Leptin: A Heavyweight Player in Obesity-Related Cancers ENSG00000168610 PMC8533426__F5 LRP-1 Matricellular Receptor Involvement in Triple Negative Breast Cancer Tumor Angiogenesis ENSG00000105329 ENSG00000134363 ENSG00000146678 ENSG00000000971 ENSG00000108821 ENSG00000122194 ENSG00000136859 ENSG00000104368 PMC3731316__F1 Gene Network Analysis of Candidate Loci for Human Anorectal Malformations ENSG00000162552 ENSG00000121644 ENSG00000144597 ENSG00000044115 ENSG00000124766 ENSG00000105656 ENSG00000166025 ENSG00000143951 ENSG00000145526 ENSG00000143125 ENSG00000110693 ENSG00000164066 ENSG00000104371 PMC2810084__F7 TLR4 signaling in effector CD4+ T cells regulates TCR activation and experimental colitis in mice ENSG00000134982 ENSG00000172936 ENSG00000136869 PMC11651285__F1 First-line treatments for KRAS-mutant non-small cell lung cancer: current state and future perspectives ENSG00000198793 ENSG00000146648 PMC8934501__SF1 GSK-3B suppression upregulates Gli1 to alleviate osteogenesis inhibition in titanium nanoparticle-induced osteolysis ENSG00000128602 PMC5595801__F2 Regulation and interaction network model of 17 cytokines ENSG00000115008 ENSG00000145839 ENSG00000125538 ENSG00000164399 ENSG00000113520 ENSG00000113525 PMC8541937__F6 Network pharmacology of triptolide in cancer cells: implications for transcription factor binding ENSG00000157554 PMC8027777__F9 Graphical illustration of proposed DEX-mediated preservation of mitochondrial fusion and fission involved in regulating HIF-1a/HO-1 pathway ENSG00000116688 ENSG00000171109 ENSG00000214253 PMC7332729__F5 Influence of MCR on critical signaling pathways involved in embryonic myogenesis ENSG00000234852 ENSG00000188064 ENSG00000196782 ENSG00000099860 ENSG00000112118 ENSG00000073111 ENSG00000112715 ENSG00000160294 ENSG00000105325 ENSG00000171720 ENSG00000112242 ENSG00000168214 ENSG00000074181 ENSG00000128917 ENSG00000130222 ENSG00000105810 ENSG00000140443 ENSG00000164619 ENSG00000177169 ENSG00000133056 ENSG00000165891 ENSG00000083290 ENSG00000136643 ENSG00000111361 ENSG00000168487 ENSG00000101224 ENSG00000117399 ENSG00000100100 ENSG00000106003 ENSG00000091073 ENSG00000135409 ENSG00000135446 ENSG00000106993 ENSG00000110200 ENSG00000161202 ENSG00000204217 ENSG00000115461 PMC8727744__F3 Targeting Myeloid-Derived Suppressor Cells to Enhance the Antitumor Efficacy of Immune Checkpoint Blockade Therapy ENSG00000111537 ENSG00000111859 ENSG00000164400 ENSG00000118520 ENSG00000168610 PMC11674667__F3 HIF signaling pathway in normoxic and hypoxic state ENSG00000087245 ENSG00000134086 ENSG00000198793 PMC8727744__F1 Targeting Myeloid-Derived Suppressor Cells to Enhance the Antitumor Efficacy of Immune Checkpoint Blockade Therapy ENSG00000108691 ENSG00000135446 ENSG00000118520 PMC4399085__F3 PRC2-independent transcriptional activation by EZH2 in cancer ENSG00000104856 ENSG00000173039 ENSG00000168036 ENSG00000162521 ENSG00000074266 ENSG00000178691 ENSG00000168610 PMC7590591__F7 Pathway of anti-tumor activity of plumbagin in bladder cancer ENSG00000135446 ENSG00000198793 ENSG00000168036 ENSG00000123374 ENSG00000105810 ENSG00000100985 PMC4614629__F1 Schematic illustration of the targets of actions by spermidine in different pathways ENSG00000198793 PMC8554324__F1 Leukemic Stem Cells: From Leukemic Niche Biology to Treatment Opportunities ENSG00000178860 ENSG00000107562 ENSG00000135218 ENSG00000026508 PMC9035692__F3 Clinical Potential of Dental Pulp Stem Cells in Pulp Regeneration: Current Endodontic Progress and Future Perspectives ENSG00000019991 ENSG00000276051 ENSG00000026103 PMC6340995__F7 SNO profile of cell death network in Chagas disease (ChD) ENSG00000100811 ENSG00000143549 ENSG00000291814 ENSG00000171560 ENSG00000062485 ENSG00000137801 PMC5803173__F4 RBM20 structure and potential TTN splicing mechanism(s) regulated by RBM20 ENSG00000203867 ENSG00000167325 PMC5803173__F1 Striated sarcomere structure and TTN-mediated signaling pathway ENSG00000188554 ENSG00000284099 ENSG00000022267 PMC6340995__F8 SNO profile of inflammation and immune responses network in Chagas disease ENSG00000100811 ENSG00000182718 ENSG00000143546 ENSG00000291814 ENSG00000135446 ENSG00000005381 ENSG00000196628 ENSG00000109689 ENSG00000062485 ENSG00000137801 PMC7801429__F4 An ER signaling pathway network identified by IMPALA using Symmans data ENSG00000109320 ENSG00000291971 ENSG00000101266 ENSG00000213341 ENSG00000043462 ENSG00000121774 ENSG00000168610 ENSG00000164305 ENSG00000160691 ENSG00000179295 ENSG00000281614 ENSG00000177189 ENSG00000163558 ENSG00000177606 ENSG00000015285 ENSG00000146648 PMC3783160__F4 Model of the interactions of Rrp1 and Rrp2 with the mediators of two branches of HR DNA repair pathway and helicases Rqh1 and Srs2 ENSG00000160214 ENSG00000175854 ENSG00000145321 ENSG00000051180 ENSG00000156384 PMC5940532__F2 Signal-transduction events in necroptosis ENSG00000111537 ENSG00000138032 ENSG00000168404 ENSG00000247077 ENSG00000164342 PMC6336706__F4 Model showing the possible pathways of neuropeptide Y-induced neuroprotective effects in Alzheimer's disease PMC9462646__F4 Phase separation in immune regulation and immune-related diseases ENSG00000183735 ENSG00000164430 PMC6846243__F7 Control case interaction visualized on RPGeNet showing the connections between NRL, NR2E3 and CRX retinal transcription factors ENSG00000105392 ENSG00000165119 ENSG00000179943 ENSG00000163914 ENSG00000128342 ENSG00000175334 ENSG00000114166 ENSG00000107223 PMC7368652__F2 GSK3B on myocarditis and dilated cardiomyopathy ENSG00000162711 ENSG00000143546 ENSG00000163220 ENSG00000125538 ENSG00000168036 ENSG00000189403 ENSG00000100985 PMC9412694__F4 Impact of Epitranscriptomics on Antiviral Innate Immunity ENSG00000117525 ENSG00000088888 ENSG00000101782 ENSG00000276561 PMC7174132__F1 Epigenetics/Epigenomics of Triterpenoids in Cancer Prevention and in Health ENSG00000143799 ENSG00000105329 ENSG00000135100 ENSG00000116044 ENSG00000170558 ENSG00000086991 ENSG00000196591 ENSG00000020633 ENSG00000150457 ENSG00000113328 ENSG00000073614 ENSG00000164362 ENSG00000172936 ENSG00000185591 ENSG00000291761 PMC5314913__F2 Activation of mTOR (mechanistic target of rapamycin) in rheumatic diseases ENSG00000111537 ENSG00000105329 ENSG00000168118 PMC10535870__F9 Targeting Autophagy, Apoptosis, and SIRT1/Nrf2 Axis with Topiramate Underlies Its Neuroprotective Effect against Cadmium-Evoked Cognitive Deficits in Rats ENSG00000198793 ENSG00000171791 PMC9429646__F1 Lipid rafts in cancer stem cell: a target to eradicate cancer ENSG00000134982 ENSG00000272398 ENSG00000026508 ENSG00000168036 ENSG00000128602 ENSG00000121966 PMC9412694__F2 Impact of Epitranscriptomics on Antiviral Innate Immunity ENSG00000213928 ENSG00000088888 ENSG00000276561 ENSG00000142166 PMC7368652__F3 Phosphorylated GSK3B on polycystin-1/2 mutation of polycystic kidney disease ENSG00000129474 ENSG00000167941 ENSG00000198793 ENSG00000168036 PMC3315579__F4 Loss of PTEN Is Not Associated with Poor Survival in Newly Diagnosed Glioblastoma Patients of the Temozolomide Era ENSG00000198793 ENSG00000146648 PMC7432215__F2 MUDENG Augmentation: A Genesis in Anti-Cancer Therapy? ENSG00000132906 ENSG00000120868 ENSG00000168040 ENSG00000164305 PMC4835624__F1 Signaling through EGFR ENSG00000198793 PMC7826796__F1 Metabolic pathway of vitamin D (based on Feldman et al., 2014 , Jekinson 2019 and Dou et al., 2016 with own modifications) ENSG00000111012 ENSG00000172893 ENSG00000019186 ENSG00000186104 ENSG00000135929 PMC7546314__F8 Cellular model summarizing potential mechanism of cucumber resistance to B ENSG00000105722 ENSG00000136997 PMC9030443__F3 Is Nucleoredoxin a Master Regulator of Cellular Redox Homeostasis? Its Implication in Different Pathologies ENSG00000167693 ENSG00000184675 ENSG00000284571 ENSG00000136869 PMC2593077__F2 Hepatitis C and Innate Immunity – Recent Advances ENSG00000183735 ENSG00000170458 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC11591800__F2 MTOR signal pathway ENSG00000143761 ENSG00000169047 ENSG00000145979 ENSG00000155792 PMC6827047__F1 Parallel outline of several physiological roles of the TGFB/p38, mitogen-activated protein kinase (MAPK), and P13k/AKT/mTOR signaling pathways ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC6827047__F3 Targeted components of the MAPK and AKT signaling cascades by small-molecule inhibitors in cancer ENSG00000157764 ENSG00000198793 PMC8702080__F1 Genetic Insights into the Impact of Complement in Alzheimer’s Disease ENSG00000039537 ENSG00000113600 ENSG00000203710 ENSG00000166278 ENSG00000062485 ENSG00000236625 PMC4152843__F5 Comparative genome-wide transcriptional analysis of human left and right internal mammary arteries ENSG00000065357 ENSG00000128322 ENSG00000113140 ENSG00000117152 ENSG00000007908 ENSG00000110324 ENSG00000102010 ENSG00000073756 ENSG00000135373 ENSG00000179163 ENSG00000019582 ENSG00000123496 ENSG00000128284 ENSG00000103490 ENSG00000170458 ENSG00000138755 ENSG00000188404 ENSG00000163734 ENSG00000164136 ENSG00000198670 ENSG00000162692 ENSG00000105287 ENSG00000182179 PMC6027262__F4 Pathway overview of Salmonella carbon metabolism under Pi starvation ENSG00000197713 ENSG00000153574 PMC6801800__F6 Endogenously derived chemerin mediates a tumor-suppressive effect through inhibition of Wnt/Beta-catenin signaling in adrenocortical carcinoma ENSG00000134982 ENSG00000168036 PMC6520904__F7 CXCR7-EGFR crosstalk and its effect on the MAPK signaling pathway ENSG00000107562 ENSG00000138798 ENSG00000146648 PMC7655184__F1 Summary scheme of the cholesterol-mediated hepatocyte and stellate cell crosstalk pathway in NASH ENSG00000163501 ENSG00000131023 PMC5561110__F12 Schematic representation of C5b-9-induced lysosomal dysfunction that inactivates autophagy in podocytes ENSG00000039537 ENSG00000113600 PMC5314913__F1 Activation of mTOR (mechanistic target of rapamycin) in rheumatic diseases ENSG00000110497 ENSG00000143761 ENSG00000198793 ENSG00000155792 ENSG00000204673 ENSG00000168610 PMC11061361__F2 LIPUS holds potential as an effective approach to counteract synovial inflammation and fibrosis ENSG00000162711 ENSG00000125538 ENSG00000284099 ENSG00000168036 PMC11061361__F3 LIPUS regulates chondrocyte function via multiple pathways ENSG00000291971 ENSG00000157766 ENSG00000198793 ENSG00000163914 ENSG00000124766 ENSG00000168036 ENSG00000112715 ENSG00000062485 PMC6610330__F4 Model illustrating potential effects of cold stress on membrane lipid pathway in peanut ENSG00000173599 ENSG00000171759 ENSG00000198670 ENSG00000184207 PMC4228940__F10 Novel Role of Vascular Endothelial Cadherin in Modulating c-Src Activation and Downstream Signaling of Vascular Endothelial Growth Factor ENSG00000291971 PMC7888617__F2 Targeting oncogenic mutations in colorectal cancer using cryptotanshinone ENSG00000140992 ENSG00000002330 ENSG00000065361 ENSG00000134982 ENSG00000138798 ENSG00000113070 ENSG00000198793 ENSG00000169047 ENSG00000168036 ENSG00000108443 ENSG00000002745 ENSG00000171791 ENSG00000121879 ENSG00000168610 ENSG00000177606 ENSG00000185591 ENSG00000146648 PMC9064865__F5 6-Hydroxydopamine Induces Neurodegeneration in Terminally Differentiated SH-SY5Y Neuroblastoma Cells via Enrichment of the Nucleosomal Degradation Pathway: a Global Proteomics Approach ENSG00000105664 ENSG00000133116 PMC7888617__F4 Targeting oncogenic mutations in colorectal cancer using cryptotanshinone ENSG00000002330 ENSG00000065361 ENSG00000134982 ENSG00000113070 ENSG00000138798 ENSG00000198793 ENSG00000136997 ENSG00000168036 ENSG00000185591 ENSG00000171791 ENSG00000146648 PMC7888617__F3 Targeting oncogenic mutations in colorectal cancer using cryptotanshinone ENSG00000002330 ENSG00000134982 ENSG00000113070 ENSG00000138798 ENSG00000198793 ENSG00000169047 ENSG00000136997 ENSG00000168036 ENSG00000185591 ENSG00000171791 ENSG00000168610 ENSG00000146648 PMC2893383__F2 Schematic of leptin signaling through STAT3 and PDE3B pathways in POMC and NT neurons in the hypothalamus ENSG00000169047 ENSG00000115138 ENSG00000168610 PMC11312684__F2 GPx4 in the ferroptosis regulatory pathway: (a) GPx4 catalytic cycle representation ENSG00000168003 ENSG00000151012 ENSG00000197429 ENSG00000113161 PMC3931425__F1 Diagram of known egg activation pathways in Drosophila, Xenopus, and mouse ENSG00000134982 ENSG00000117399 PMC11550995__F5 Noncoding RNAs in rheumatoid arthritis: modulators of the NFKB signaling pathway and therapeutic implications ENSG00000104856 ENSG00000172936 ENSG00000111321 ENSG00000127191 ENSG00000168610 ENSG00000146648 PMC8615218__F3 Siglecs as Therapeutic Targets in Cancer ENSG00000291971 PMC11550995__F3 NFKB signaling pathway ENSG00000104856 ENSG00000172936 ENSG00000111321 ENSG00000127191 ENSG00000168610 ENSG00000146648 PMC11312684__F1 GSH synthesis and transport of precursor amino acids: (a) Gamma-Glutamyl cycle of GSH synthesis ENSG00000168003 ENSG00000115902 ENSG00000151012 ENSG00000026508 ENSG00000103257 ENSG00000115419 PMC11868168__F4 Metastasis from other organs to lungs via exosomes ENSG00000107562 ENSG00000127528 ENSG00000132510 ENSG00000187772 ENSG00000136826 PMC4171341__F3 Change or Die: Targeting Adaptive Signaling to Kinase Inhibition in Cancer Cells ENSG00000177169 ENSG00000002330 ENSG00000169047 ENSG00000198793 ENSG00000196712 PMC9638134__F6 Comprehensive analysis of endoplasmic reticulum stress and immune infiltration in major depressive disorder ENSG00000095585 ENSG00000149311 ENSG00000170909 ENSG00000213928 ENSG00000226275 ENSG00000111537 ENSG00000213658 ENSG00000113595 ENSG00000186716 ENSG00000083799 ENSG00000143387 PMC11868168__F3 Lung cancer metastasizes outward through exosomes ENSG00000124766 ENSG00000142082 PMC3159098__F2 Different RNA processing events in mammals ENSG00000182173 ENSG00000275165 ENSG00000198860 ENSG00000146282 ENSG00000179988 ENSG00000154743 PMC9659743__F2 Dynamic and static biomechanical traits of cardiac fibrosis ENSG00000175054 ENSG00000163914 ENSG00000103335 PMC8262210__F5 Wnt3a/Beta-Catenin/CBP Activation in the Progression of Cervical Intraepithelial Neoplasia ENSG00000154342 ENSG00000168036 ENSG00000136826 PMC5297658__F1 Representative apoptosis pathway and associated factors ENSG00000168040 ENSG00000026103 PMC4832395__F4 Regulation of de novo lipogenesis by SREBP1c and ChREBP ENSG00000180210 ENSG00000262785 ENSG00000170522 ENSG00000026103 PMC3683958__F3 The dynamic regulation of NAD metabolism in mitochondria ENSG00000105835 ENSG00000291814 ENSG00000123572 PMC11889932__F4 Regulation of ferroptosis through the interaction of iron metabolism and the STAT3/NRF2 pathway ENSG00000151012 ENSG00000060491 ENSG00000167468 ENSG00000168610 ENSG00000115107 ENSG00000106546 ENSG00000079999 PMC3912738__F1 IGF signaling involvement in EMT ENSG00000169291 ENSG00000169047 PMC7484674__F6 Top 3 modules with relatively high scores from the protein-protein interaction network ENSG00000163464 ENSG00000008438 ENSG00000139572 ENSG00000170909 ENSG00000172322 ENSG00000107562 ENSG00000196187 ENSG00000135218 ENSG00000059804 ENSG00000110203 ENSG00000077152 ENSG00000163739 ENSG00000171049 ENSG00000284982 ENSG00000123485 ENSG00000124107 ENSG00000124875 ENSG00000173391 ENSG00000096006 ENSG00000274513 ENSG00000158869 ENSG00000229314 ENSG00000173930 ENSG00000104918 ENSG00000118520 ENSG00000162747 ENSG00000148346 ENSG00000035499 ENSG00000109743 ENSG00000257335 ENSG00000163661 ENSG00000117399 ENSG00000129173 ENSG00000133048 ENSG00000134827 ENSG00000100985 ENSG00000168081 PMC11889932__F3 Regulation of ferroptosis by JAK/STAT signaling pathways, focusing on the roles of different STAT proteins, including STAT1, STAT3, and STAT6, in modulating ferroptosis through pathways like SLC7A11 and GPX4 (Amino acid metabolism) ENSG00000169245 ENSG00000186810 ENSG00000151012 ENSG00000115415 ENSG00000167468 ENSG00000168610 ENSG00000162298 PMC11889932__F2 This diagram illustrates the interconnected pathways involved in ferroptosis ENSG00000161905 ENSG00000167468 ENSG00000111684 ENSG00000115107 ENSG00000079999 PMC3912738__F5 Proposed model for the interaction between Shh and IGF signaling ENSG00000168283 ENSG00000169047 ENSG00000198793 ENSG00000164690 ENSG00000128602 PMC3912738__F4 The cross-talks between the Notch and the IGF signaling ENSG00000169047 ENSG00000198793 PMC11889932__F6 Ferroptosis and STAT signaling pathways by various compounds in cancer models ENSG00000161905 ENSG00000115415 ENSG00000167468 ENSG00000137409 ENSG00000111684 ENSG00000145321 ENSG00000168610 PMC3912738__F3 The interplay between the canonical Wnt/Beta-catenin pathway and IGF signaling ENSG00000138795 ENSG00000134982 ENSG00000169047 ENSG00000198793 ENSG00000168036 PMC11889932__F5 Interaction of lipid metabolism pathways of ferroptosis with STAT proteins in human diseases ENSG00000151726 ENSG00000161905 ENSG00000115415 ENSG00000111684 ENSG00000125347 ENSG00000168610 PMC6677151__F6 The inhibitory effect of Gal-3BP on TAK1-dependent NFKB signaling pathway ENSG00000102871 ENSG00000108679 ENSG00000125538 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC4084431__F1 Genes directly related to dopamine functioning ENSG00000276825 ENSG00000184845 ENSG00000169676 ENSG00000149295 PMC3000440__F1 Decorin effects as an antiproliferative (left panel) and proliferative (right panel) molecule ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC12066429__F5 Metabolic pathway reconstruction of M ENSG00000205795 ENSG00000168040 PMC11818536__F3 Tumor suppression and promoting mechanisms of LACTB ENSG00000103642 ENSG00000151012 ENSG00000122691 ENSG00000167468 ENSG00000198793 PMC9476737__F4 Cytotoxicity of oleanane type triterpene from leaf extract of Pterospermum acerifolium (in vitro) and theoretical investigation of inhibitory signaling pathway ENSG00000198793 PMC7468896__F7 LncRNA GAS5 attenuates fibroblast activation through inhibiting Smad3 signaling PMC5696504__F7 Osteogenic Wnt/Beta-catenin pathway and its interplay with polyphenols ENSG00000134982 ENSG00000167941 ENSG00000168036 PMC3918413__F4 Transforming growth factorB (TGFB) signalling pathway ENSG00000170365 ENSG00000198742 PMC3619006__F1 Proposed model for PDGF-D signaling pathway that controls the processes of EMT ENSG00000170962 ENSG00000198793 ENSG00000121966 PMC2647780__F1 Signaling Logic of Activity-Triggered Dendritic Protein Synthesis ENSG00000167658 PMC5733023__F9 A schematic depicting the role of TLR4-NFkB-Caspase-11 signaling pathway in METH-induced astrocyte-related neuroinflammation ENSG00000162711 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC4176946__F2 Ketone bodies as signaling metabolites ENSG00000105550 ENSG00000124523 ENSG00000096717 ENSG00000142082 ENSG00000089163 PMC4736186__F11 Schema of signaling pathway involved in IL-1Beta-induced inflammation in microglia ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000115594 PMC6707123__F2 Schematic representation of the neural circuitry underlying the control of circadian rhythms ENSG00000214285 PMC8875753__F1 miR-294 and miR-410 Negatively Regulate Tnfa, Arginine Transporter Cat1/2, and Nos2 mRNAs in Murine Macrophages Infected with Leishmania amazonensis ENSG00000081181 ENSG00000118520 ENSG00000007171 PMC7831311__F7 Important pathways affected by long-term 1-MCP treatment ENSG00000131473 ENSG00000100412 ENSG00000091140 ENSG00000062485 ENSG00000084774 PMC11014885__F4 Endosymbiont Tremblaya phenacola influences the reproduction of cotton mealybugs by regulating the mechanistic target of rapamycin pathway ENSG00000139531 PMC3761221__F4 Fear learning and memory across adolescent development Hormones and Behavior Special Issue: Puberty and Adolescence ENSG00000164879 PMC4428600__F1 Wnting out ocular neovascularization: using nanoparticle delivery of VLDL receptor extracellular domain as Wnt pathway inhibitor in the retina ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC5673678__F4 iCOS pathway associated with HIV-1 TAR target genesiCOS signaling in T helper cells ENSG00000033327 ENSG00000002330 ENSG00000134982 ENSG00000141968 PMC4723085__F4 Uncovering New Pathogen–Host Protein–Protein Interactions by Pairwise Structure Similarity ENSG00000109332 ENSG00000185386 ENSG00000100906 ENSG00000072401 ENSG00000101843 ENSG00000011485 ENSG00000185104 PMC6608049__F2 Molecular pathways involved in the maintenance of the MDSC suppressive function.A wide variety of proinflammatory factors are involved in the induction of the suppressive function in MDSCs ENSG00000019582 ENSG00000115415 ENSG00000164399 ENSG00000113520 ENSG00000104432 ENSG00000168610 ENSG00000113525 PMC9309082__F2 Copper in the tumor microenvironment and tumor metastasis ENSG00000138336 ENSG00000177556 ENSG00000291761 PMC10878147__F1 Illustration represents the polyphenols targeting the NFKB pathway associated with Alzheimer's disease ENSG00000162711 ENSG00000142192 PMC4823852__F8 MicroRNAs upregulated in OSCC repress multiple genes in the p53 signaling pathway ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000136997 ENSG00000123374 ENSG00000112378 ENSG00000196470 ENSG00000164305 ENSG00000126458 ENSG00000026103 PMC4823852__F7 MicroRNAs downregulated in OSCC target multiple genes in the PI3K/AKT pathway ENSG00000177455 ENSG00000124102 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000213341 ENSG00000152430 PMC7765227__F3 Signal transducer and activator of transcription (STAT)1 and STAT3 pathways in the inflammatory response ENSG00000115415 ENSG00000137193 ENSG00000168610 ENSG00000276561 ENSG00000182179 PMC7765227__F2 Role of the inflammation-associated transcription factor signaling pathway (NFKB) and mitogen-activated protein kinase (MAPK) pathways in the inflammatory response ENSG00000125538 ENSG00000172936 ENSG00000162692 ENSG00000175104 PMC3342067__F4 CD44 potentiates T cell activation, expansion, contraction, and maintenance of memory cells ENSG00000291603 ENSG00000134982 ENSG00000026508 ENSG00000064012 ENSG00000168685 ENSG00000026103 PMC8961894__F1 DNA in extracellular vesicles: from evolution to its current application in health and disease ENSG00000168461 ENSG00000110651 ENSG00000010278 ENSG00000135404 PMC5074356__F1 Signal transduction mediated by the extracellular calcium-sensing receptor (CaR) PMC2814543__F4 Nutrient sensing and inflammation in metabolic diseases ENSG00000198793 PMC6196465__F5 Lipid synthesis pathway in porcine mammary gland ENSG00000214456 ENSG00000135218 ENSG00000169710 ENSG00000099194 ENSG00000101577 ENSG00000158125 ENSG00000111058 ENSG00000134824 ENSG00000292170 ENSG00000149485 ENSG00000066322 ENSG00000285482 ENSG00000123983 PMC6196465__F3 Milk protein synthesis pathway in porcine mammary gland ENSG00000086730 PMC6196465__F2 Lactose synthesis pathway in porcine mammary gland ENSG00000159399 PMC2715245__F7 Comparison of models for FRAXA and APC-inducible chromosome fragility ENSG00000149311 ENSG00000175054 ENSG00000134982 PMC4175348__F11 A putative scheme for ATF3-mediated regulation of ER stress-induced cancer chemokine expression ENSG00000162772 PMC7847067__F1 Adropin: a hepatokine modulator of vascular function and cardiac fuel metabolism ENSG00000148400 PMC4919024__F6 The pathway of EGF induced anticipatory UPR activation ENSG00000100290 ENSG00000144895 ENSG00000138798 PMC4184971__F4 Transcriptome analysis reveals a dynamic and differential transcriptional response to sulforaphane in normal and prostate cancer cells and suggests a role for Sp1 in chemoprevention ENSG00000137275 ENSG00000065559 ENSG00000116030 ENSG00000168040 ENSG00000104081 ENSG00000084774 PMC11541728__F2 Signalling pathway of ephrin receptors (EphR) is depicted ENSG00000070831 ENSG00000291971 ENSG00000163914 PMC6445055__F6 Gene networks and canonical pathways generated by Ingenuity Pathway Analysis ENSG00000135899 ENSG00000134086 ENSG00000118363 ENSG00000198755 ENSG00000156482 ENSG00000078668 ENSG00000053372 PMC4797117__F2 ML-hGRN for putative pluripotency renewal pathway in human embryonic stem cells ENSG00000084093 ENSG00000213015 ENSG00000120837 ENSG00000147596 ENSG00000188342 ENSG00000115816 ENSG00000168610 ENSG00000136603 ENSG00000043355 ENSG00000136960 ENSG00000102098 ENSG00000156925 ENSG00000121570 PMC4811486__F5 NF-Y activates genes of metabolic pathways altered in cancer cells ENSG00000228716 ENSG00000125166 ENSG00000065911 ENSG00000135069 ENSG00000163738 ENSG00000112992 ENSG00000145020 ENSG00000146733 ENSG00000164933 ENSG00000178445 ENSG00000120254 ENSG00000284320 ENSG00000168003 ENSG00000065833 ENSG00000291958 ENSG00000198380 ENSG00000092621 ENSG00000145321 ENSG00000036565 ENSG00000082212 ENSG00000091140 ENSG00000115419 ENSG00000084774 ENSG00000167701 PMC7702664__F5 Visualization of KEGG pathway of the genes altered in the CUBN neighborhood in CRC ENSG00000121207 PMC8415109__F1 Non-coding RNA Activated by DNA Damage: Review of Its Roles in the Carcinogenesis ENSG00000087095 ENSG00000167601 ENSG00000126016 ENSG00000186575 ENSG00000156299 ENSG00000089685 ENSG00000144560 ENSG00000136997 ENSG00000168036 ENSG00000007047 ENSG00000131023 ENSG00000102974 PMC7382314__F7 Non-canonical cholinergic anti-inflammatory pathway-mediated activation of peritoneal macrophages induces Hes1 and blocks ischemia/reperfusion injury in the kidney ENSG00000114315 PMC2720031__F1 GR signal transduction pathway ENSG00000047410 PMC8206466__F1 Tyrosol as a Neuroprotector: Strong Effects of a “Weak” Antioxidant ENSG00000171791 ENSG00000168610 PMC6485955__F4 FGF21 Signaling Network in Adipocytes ENSG00000033327 ENSG00000105550 ENSG00000136937 ENSG00000198793 ENSG00000170653 ENSG00000065559 ENSG00000167965 ENSG00000077782 ENSG00000160741 ENSG00000162599 PMC5467317__F1 Cholesterol and isoprenoid synthesis pathway which shows the inhibition of 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase by statins ENSG00000070831 PMC5434646__F6 Proposed mechanism of the interplay between mitochondrial complex II and FH in the stabilization of the HIFA signaling pathway ENSG00000143252 ENSG00000073578 ENSG00000117118 PMC6839211__F8 MicroRNA-182 in ovarian cancer ENSG00000131153 ENSG00000168036 ENSG00000112118 ENSG00000176105 ENSG00000073111 ENSG00000091651 ENSG00000076003 ENSG00000124762 ENSG00000166508 ENSG00000093009 ENSG00000072571 ENSG00000137807 ENSG00000089685 ENSG00000115942 ENSG00000135336 ENSG00000051180 ENSG00000105810 ENSG00000147536 ENSG00000114346 ENSG00000131747 ENSG00000139618 ENSG00000198901 ENSG00000094804 ENSG00000065328 ENSG00000101003 ENSG00000135446 ENSG00000143476 ENSG00000109805 ENSG00000010810 PMC5946182__F4 Proposed anti-inflammatory pathways based on reviewed nutritional interventions ENSG00000132693 PMC8466575__F8 Advances in Intracellular Calcium Signaling Reveal Untapped Targets for Cancer Therapy ENSG00000144935 ENSG00000134982 ENSG00000165527 PMC12103778__F5 Cytoneme-mediated Wnt signaling in gastric cancer ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000277641 PMC12103778__F4 Cytoneme-mediated self-organization and asymmetric cell division in stem cells ENSG00000154342 ENSG00000168036 PMC9198382__F4 Advances in the systemic treatment of therapeutic approaches in biliary tract cancer ENSG00000157764 PMC8468691__F6 4-Hydroxyderricin Promotes Apoptosis and Cell Cycle Arrest through Regulating PI3K/AKT/mTOR Pathway in Hepatocellular Cells ENSG00000134057 ENSG00000135446 ENSG00000198793 ENSG00000120868 PMC3248149__F3 Insights into 4E-BP1 and p53 mediated regulation of accelerated cell senescence ENSG00000148935 PMC3175103__F4 Dysregulated TRK Signalling is a Therapeutic Target in CYLD Defective Tumours ENSG00000185652 ENSG00000083799 ENSG00000171791 ENSG00000166484 ENSG00000069956 ENSG00000185651 ENSG00000175104 PMC3248149__F1 Insights into 4E-BP1 and p53 mediated regulation of accelerated cell senescence PMC4302087__F3 MiR-101 network regulates EMT ENSG00000169554 ENSG00000168036 PMC5499908__F1 Force transmission and mechanotransduction from the extracellular matrix (ECM) to the nucleus ENSG00000164828 ENSG00000196588 ENSG00000143815 ENSG00000163914 ENSG00000168036 ENSG00000111816 PMC3066468__F7 Scheme of cross-talk interactions between liver IR and TIM-1 signaling ENSG00000081041 ENSG00000163739 ENSG00000125538 PMC10534675__F1 Recent Advances in the Treatment of Pulmonary Arterial Hypertension Associated with Connective Tissue Diseases ENSG00000171759 ENSG00000204217 PMC5070052__F4 Schematic presentation of how the rs17228616 single-nucleotide polymorphism (SNP) in the acetylcholinesterase (AChE) gene may affect the vulnerability to stress ENSG00000070831 ENSG00000087085 PMC3576812__F1 The hedgehog’s tale: developing strategies for targeting cancer ENSG00000128602 PMC2575905__F1 Current concepts of the amino acid signaling pathway leading to protein synthesis ENSG00000284161 PMC4621105__F2 Common cellular processes important in coronavirus replication ENSG00000182481 ENSG00000105722 ENSG00000150316 ENSG00000151353 ENSG00000165280 ENSG00000108654 ENSG00000171863 ENSG00000100263 ENSG00000008988 ENSG00000107862 ENSG00000166471 ENSG00000112299 ENSG00000167088 ENSG00000184113 ENSG00000137876 ENSG00000005243 ENSG00000099194 ENSG00000104408 ENSG00000165630 ENSG00000130810 ENSG00000100029 ENSG00000164163 ENSG00000171566 ENSG00000101161 ENSG00000100387 ENSG00000175390 ENSG00000096401 ENSG00000047315 ENSG00000133135 PMC9300927__F6 Identification of circRNA–miRNA–mRNA Regulatory Network and Crucial Signaling Pathway Axis Involved in Tetralogy of Fallot ENSG00000182481 ENSG00000140564 ENSG00000153094 ENSG00000130758 ENSG00000138829 ENSG00000166025 ENSG00000164236 ENSG00000147121 ENSG00000166147 ENSG00000124702 ENSG00000121966 ENSG00000106683 ENSG00000184602 ENSG00000117525 ENSG00000112242 ENSG00000130164 ENSG00000112182 ENSG00000150051 ENSG00000137267 ENSG00000115107 ENSG00000282899 ENSG00000171885 ENSG00000189067 ENSG00000148411 ENSG00000151012 ENSG00000138131 ENSG00000164761 ENSG00000077585 ENSG00000134986 ENSG00000124766 ENSG00000161642 ENSG00000131941 ENSG00000168610 ENSG00000188389 ENSG00000150893 ENSG00000139219 ENSG00000170961 ENSG00000180447 ENSG00000134247 ENSG00000182175 ENSG00000138336 ENSG00000106780 ENSG00000118785 ENSG00000109572 ENSG00000171848 ENSG00000163638 PMC5308720__F6 Expression/activation of A5B1 integrin is linked to the Beta-catenin signaling pathway to drive migration in glioma cells ENSG00000168036 PMC6775302__F9 Proposed signaling network of regulating the formation and development of seminal vesicle tumors in TRAMP mice ENSG00000134057 ENSG00000135446 ENSG00000138798 ENSG00000105810 ENSG00000168610 ENSG00000146648 PMC6202086__F4 The mechanisms involved in the maintenance of b[Ca2+]i ENSG00000198626 ENSG00000138741 PMC6896088__F3 Associations between the autophagy pathway and MAPK signaling in to tumor tolerance against targeted therapies and chemotherapies ENSG00000128272 ENSG00000162772 ENSG00000070669 ENSG00000057663 PMC6836113__F10 Continuous impaired insulin signalling causes the activation of AD markers (GSK3B and TAU genes), thus increasing the amyloid beta aggregations leading to AD ENSG00000205221 PMC8415109__F3 Non-coding RNA Activated by DNA Damage: Review of Its Roles in the Carcinogenesis ENSG00000067900 ENSG00000089159 PMC7021704__F6 Main pathways in O ENSG00000069482 PMC3492204__F5 A simplified scheme to illustrate the dual roles played by KIF7 in Indian Hedgehog (IHh) signaling and chondrocytes development ENSG00000166813 ENSG00000128602 ENSG00000163501 PMC6394552__F4 A feedforward mechanism in TGFB signaling ENSG00000198742 PMC11989323__F2 Biosynthetic pathway of NAPE and NAE ENSG00000138744 ENSG00000117480 ENSG00000100439 ENSG00000006007 PMC10037406__F5 Posttranslational modification in the cGAS-STING pathway ENSG00000106785 ENSG00000112343 ENSG00000119401 ENSG00000204977 ENSG00000159461 ENSG00000137699 ENSG00000265491 ENSG00000169871 ENSG00000090432 ENSG00000163904 ENSG00000183735 ENSG00000164430 ENSG00000135912 ENSG00000170703 ENSG00000138942 ENSG00000173456 PMC10037406__F1 CGAS-STING signaling pathway ENSG00000183735 ENSG00000164430 PMC6160542__F1 Fibrogenic secretome pathways in the development of fibrosis ENSG00000281324 ENSG00000162337 ENSG00000050165 ENSG00000168036 ENSG00000096717 PMC6714585__F21 Most potent small molecules capable of inhibiting Hh pathway with their mode of action ENSG00000164690 ENSG00000128602 PMC9259561__F4 PD-L1 regulates cell proliferation and apoptosis in acute myeloid leukemia by activating PI3K-AKT signaling pathway ENSG00000070193 ENSG00000259207 ENSG00000005961 ENSG00000110799 ENSG00000100448 ENSG00000138798 ENSG00000189056 ENSG00000169047 ENSG00000163737 ENSG00000104368 ENSG00000151276 ENSG00000277571 ENSG00000206384 ENSG00000127533 ENSG00000164946 ENSG00000178732 ENSG00000172752 ENSG00000152952 ENSG00000005381 PMC8366450__F5 Human CPPED1 belongs to calcineurin‐like metallophosphoesterase superfamily and dephosphorylates PI3K‐AKT pathway component PAK4 ENSG00000005882 ENSG00000040199 ENSG00000103381 ENSG00000130669 PMC5329687__F1 Nitric oxide dose effect on mitochondrial function and endoplasmic reticulum stress ENSG00000241186 ENSG00000198125 PMC8880704__F9 Network Pharmacology Study to Reveal the Potentiality of a Methanol Extract of Caesalpinia sappan L. Wood against Type-2 Diabetes Mellitus ENSG00000140992 ENSG00000151376 ENSG00000151726 ENSG00000135218 ENSG00000112972 ENSG00000167114 ENSG00000167910 ENSG00000165269 ENSG00000173391 ENSG00000099194 ENSG00000157184 ENSG00000117054 ENSG00000167772 ENSG00000150991 ENSG00000134824 ENSG00000161533 ENSG00000180432 ENSG00000100979 ENSG00000115361 ENSG00000158874 ENSG00000124253 ENSG00000083807 ENSG00000113790 ENSG00000135929 PMC3443185__F1 Two mechanisms underlying circadian control of NFKB response ENSG00000132326 PMC11573773__F3 Regulatory pathways of ABCC5 in cancer ENSG00000114770 ENSG00000168283 ENSG00000079999 PMC11573773__F2 SLC34A2-Bmi1-ABCC5 signalling pathway hypothesis diagram ENSG00000114770 ENSG00000168283 ENSG00000157765 PMC4640739__F7 Working model for Mek/Erk signaling in mouse ESCs ENSG00000147596 ENSG00000135111 ENSG00000136826 PMC3889255__F1 CRH signaling pathway - This map represents the NetPath reactions of CRH signaling pathway ENSG00000143799 ENSG00000157764 ENSG00000100906 ENSG00000109320 ENSG00000078369 ENSG00000173039 ENSG00000117298 ENSG00000088256 ENSG00000171791 ENSG00000169032 ENSG00000182459 ENSG00000196628 ENSG00000141480 ENSG00000177606 ENSG00000137203 ENSG00000115138 ENSG00000197943 ENSG00000124181 PMC9221189__F5 O-GlcNAcylation: An Emerging Protein Modification Regulating the Hippo Pathway ENSG00000147162 ENSG00000281324 ENSG00000162337 ENSG00000128917 ENSG00000163914 ENSG00000168036 ENSG00000150457 ENSG00000131023 ENSG00000196628 PMC2926749__F4 Proposed model for MALT1 function in NFKB activation ENSG00000186716 ENSG00000175104 PMC9536081__F6 Absence of ID2 results in an altered photic responsiveness of the circadian system ENSG00000179094 PMC8616424__F1 Dissecting the Crosstalk between Endothelial Mitochondrial Damage, Vascular Inflammation, and Neurodegeneration in Cerebral Amyloid Angiopathy and Alzheimer’s Disease ENSG00000162711 ENSG00000239732 ENSG00000164430 ENSG00000135218 ENSG00000125538 PMC9365986__F2 Immunoregulation effect of tumor microenvironment in pancreatic ductal adenocarcinoma ENSG00000272398 ENSG00000026508 ENSG00000168036 PMC4425275__F3 Original and reduced EGFR models ENSG00000138798 ENSG00000146648 ENSG00000064300 PMC8761737__F8 Transcriptomic and Histological Analysis of Exacerbated Immune Response in Multidrug-Resistant Pseudomonas aeruginosa in a Murine Model of Endophthalmitis ENSG00000100234 ENSG00000162711 ENSG00000131095 ENSG00000005381 ENSG00000175104 PMC6186418__F2 YAP/TAZ upstream signals and downstream responses ENSG00000281324 ENSG00000162337 ENSG00000156299 ENSG00000134982 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC6757264__F7 Mitogen-activated protein kinase signaling pathway in lung squamous cell carcinoma ENSG00000087095 ENSG00000163930 ENSG00000170458 ENSG00000177606 ENSG00000175104 ENSG00000026103 PMC5302973__F7 Twist1-induced epithelial-mesenchymal transition according to microsatellite instability status in colon cancer cells ENSG00000122691 ENSG00000026508 ENSG00000168036 PMC6981639__F1 The primary metabolic pathway of mammalian gangliosides ENSG00000176597 ENSG00000135454 ENSG00000111728 ENSG00000101638 ENSG00000196743 ENSG00000158470 ENSG00000115525 ENSG00000148154 PMC2696359__F1 TNF-Induced MAP Kinase Activation Oscillates in Time ENSG00000102871 ENSG00000105401 ENSG00000056558 ENSG00000127191 PMC8171813__F1 Immune cell involvement after cardiac injury ENSG00000162711 ENSG00000121807 ENSG00000132693 PMC8326758__F1 Fibroblast Growth Factor 21 in Diabetic Cardiovascular Complications and Related Epigenetic Mechanisms ENSG00000105550 ENSG00000005421 ENSG00000010810 PMC8698717__F3 Neutrophils and Platelets: Immune Soldiers Fighting Together in Stroke Pathophysiology ENSG00000110799 ENSG00000162692 PMC3797807__F4 Cell Survival Following Radiation Exposure Requires miR-525-3p Mediated Suppression of ARRB1 and TXN1 ENSG00000197442 ENSG00000265972 ENSG00000277273 ENSG00000171791 ENSG00000106546 ENSG00000136997 ENSG00000011485 ENSG00000115419 ENSG00000115594 ENSG00000169567 ENSG00000132906 ENSG00000165119 ENSG00000156738 ENSG00000173039 ENSG00000007908 ENSG00000140465 ENSG00000023909 ENSG00000007171 ENSG00000019582 ENSG00000158290 ENSG00000177189 ENSG00000111537 ENSG00000100387 ENSG00000141480 ENSG00000133112 ENSG00000175104 PMC4168754__F1 Cardiac Hypertrophic Response pathway loaded as a pathway ENSG00000105664 ENSG00000101751 ENSG00000198793 ENSG00000277273 ENSG00000108840 PMC9345703__F8 Pharmacologically Active Alkaloid Cryptolepine Activates a Type 1 Interferon Response That Is Independent of MAVS and STING Pathways ENSG00000183735 ENSG00000164430 ENSG00000115415 ENSG00000185745 ENSG00000111331 ENSG00000164342 ENSG00000142166 PMC6459169__F4 Transcriptional coverage of penguin transcripts on the vertebrate Janus kinase/signal transducers and activators of transcription (JAK-STAT) (#04630) (A) and vertebrate Toll-like receptor (TLR) signaling pathway (#04620) (B) ENSG00000213658 ENSG00000170458 ENSG00000198517 ENSG00000087842 PMC7765985__F2 Networks generated from genes altered in intestinal- and diffuse-type gastric cancer (GC) ENSG00000006451 ENSG00000171759 PMC6459169__F3 Transcriptional coverage of penguin transcripts within the vertebrate nuclear factor kappa B (NFKB) signaling pathway (#04064) ENSG00000095585 ENSG00000226275 ENSG00000213658 ENSG00000175104 ENSG00000135517 PMC11936485__F8 Mechanism and signaling pathways of the inhibitory effects of HST on the proliferation of LUSC cells ENSG00000144895 ENSG00000148400 ENSG00000134057 ENSG00000164305 PMC7473788__F5 Working model proposing how TFAP2C functions downstream of the Hippo signaling pathway to regulate Cdx2 expression in the outside polar cells ENSG00000087510 ENSG00000165556 ENSG00000126016 ENSG00000186575 ENSG00000197905 ENSG00000150457 ENSG00000131023 PMC7473788__F4 Working model proposing how TFAP2C and TEAD4 promote formation of the apical domain, which in turn, negatively regulate LATS1/2 activity in the outside polar cells ENSG00000087510 ENSG00000197905 ENSG00000067900 ENSG00000150457 ENSG00000131023 ENSG00000124171 PMC7473788__F3 The Hippo signaling pathway in mouse preimplantation embryos ENSG00000165556 ENSG00000126016 ENSG00000186575 ENSG00000197905 ENSG00000018408 ENSG00000150457 ENSG00000131023 PMC9221189__F1 O-GlcNAcylation: An Emerging Protein Modification Regulating the Hippo Pathway ENSG00000198670 ENSG00000150457 ENSG00000131023 PMC183833__F2 Canonical Wnt/Beta-catenin pathway ENSG00000162337 ENSG00000134982 ENSG00000165879 ENSG00000168036 PMC4015472__F3 Post-Transcriptional Regulation of Interferons and Their Signaling Pathways ENSG00000159128 ENSG00000138378 ENSG00000111537 ENSG00000115415 ENSG00000027697 PMC4015472__F2 Post-Transcriptional Regulation of Interferons and Their Signaling Pathways ENSG00000105397 ENSG00000092054 ENSG00000078814 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000142166 PMC9530146__F6 Mechanisms of acupuncture for neuropathic pain based on somatosensory system ENSG00000168329 PMC3504364__F2 Methotrexate (MTX) mechanisms of action in the folate metabolic pathway ENSG00000228716 ENSG00000100714 ENSG00000173638 ENSG00000136877 ENSG00000103222 ENSG00000124275 ENSG00000137563 ENSG00000118777 ENSG00000023839 PMC4419202__F4 Upstream analysis focused on transcription factors after Foxa1 knockout in female bladders ENSG00000071564 ENSG00000104856 ENSG00000186395 ENSG00000141384 ENSG00000148400 ENSG00000080839 PMC4419202__F3 Most enriched pathways after Foxa1 knockout in female bladders ENSG00000104856 ENSG00000186395 ENSG00000263243 ENSG00000163736 ENSG00000162924 PMC6534496__F6 Outline of the main altered pathways in SiNETs ENSG00000281324 ENSG00000162337 ENSG00000134569 ENSG00000134982 ENSG00000291971 ENSG00000198793 ENSG00000168036 ENSG00000124762 ENSG00000134086 ENSG00000132781 ENSG00000163251 ENSG00000113318 ENSG00000057468 ENSG00000170430 ENSG00000095002 ENSG00000146648 ENSG00000151151 ENSG00000122512 PMC4419202__F1 Most enriched pathways after Foxa1 knockout in male bladders ENSG00000229314 PMC8302727__F2 Proposed biosynthetic pathway of ARTs based on the two-polyketide-chain assembly model ENSG00000111339 PMC10904539__F2 AhR in tumor energy metabolism ENSG00000101945 ENSG00000159399 ENSG00000106546 PMC8402591__F1 Efficacy of COVID-19 Vaccines in Chronic Kidney Disease and Kidney Transplantation Patients: A Narrative Review ENSG00000134982 ENSG00000198793 PMC6005849__F4A Resolvin E1 Promotes Bone Preservation Under Inflammatory Conditions ENSG00000111537 ENSG00000101146 ENSG00000083799 ENSG00000143387 PMC6956807__F8 Proposed model for miR-204-5p-SNAI2/SUZ12/HDAC1/JAK2/STAT3 regulatory circuit in HNSCC progression ENSG00000019549 ENSG00000178691 ENSG00000168610 PMC9310501__F4 STAT3-mediated osteogenesis and osteoclastogenesis in osteoporosis ENSG00000170909 ENSG00000128342 ENSG00000100985 ENSG00000168610 PMC8845065__F6 Retinoic acid synthesis and signaling ENSG00000184254 ENSG00000128918 ENSG00000143320 ENSG00000073737 PMC9310501__F3 STAT3-mediated osteogenesis and osteoclastogenesis in osteoporosis ENSG00000162552 ENSG00000245848 ENSG00000168036 ENSG00000128342 ENSG00000168610 ENSG00000291973 PMC8385858__F8 Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer ENSG00000087245 ENSG00000135446 ENSG00000171791 PMC11019011__F3 Traditional Chinese medicine in osteoporosis: from pathogenesis to potential activity ENSG00000150782 ENSG00000088305 ENSG00000163914 ENSG00000168036 ENSG00000168646 ENSG00000165617 PMC4280579__F7 Integrated model of NDV-3–mediated protective efficacy versus MRSA in murine SSSI ENSG00000134982 ENSG00000168610 PMC11019011__F5 Traditional Chinese medicine in osteoporosis: from pathogenesis to potential activity ENSG00000150782 ENSG00000131196 PMC11019011__F4 Traditional Chinese medicine in osteoporosis: from pathogenesis to potential activity ENSG00000170365 PMC7582838__F2 Modified tricarboxylic acid (TCA) pathway in cyanobacteria PMC11019011__F6 Traditional Chinese medicine in osteoporosis: from pathogenesis to potential activity ENSG00000150782 ENSG00000131196 PMC5002299__F3 Regulation of the NLRP3 inflammasome activation by the ubiquitin-proteasome system ENSG00000162711 ENSG00000185515 ENSG00000131323 ENSG00000175104 PMC5002299__F1 Regulation of TLR4 signalling by the ubiquitin-proteasome system ENSG00000184979 ENSG00000135655 ENSG00000136878 ENSG00000172005 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000083799 ENSG00000154124 ENSG00000162601 ENSG00000175104 PMC4384737__F2 Nucleotide sugar UDP-GlcNAc resides at the nexus of protein and lipid glycosylation ENSG00000047410 ENSG00000147162 ENSG00000198408 ENSG00000013375 PMC8394439__F1 Microbiota-Associated Metabolites and Related Immunoregulation in Colorectal Cancer ENSG00000089692 ENSG00000145321 ENSG00000049768 PMC3825415__F3 FGFR signaling pathway ENSG00000187682 ENSG00000107338 ENSG00000110395 ENSG00000070831 ENSG00000163914 PMC3756518__F1 Schematic of the simplified B-cell receptor (BCR) signaling pathway simulated in our Monte Carlo method ENSG00000186716 PMC10300974__F5 Hypericum perforatum L. and the Underlying Molecular Mechanisms for Its Choleretic, Cholagogue, and Regenerative Properties † ENSG00000081041 ENSG00000143546 ENSG00000291971 ENSG00000146648 PMC8005494__F2 Molecular mechanism of pyroptosis ENSG00000278718 ENSG00000145649 ENSG00000189403 ENSG00000168610 ENSG00000147697 ENSG00000073605 PMC4068285__F4 LM infection in microglia ENSG00000002330 ENSG00000170458 ENSG00000115415 ENSG00000277943 ENSG00000138760 PMC9557975__F2 Activation of TLR4 by viral glycoproteins: A double-edged sword? ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC4253844__F2 Cholesterol in brain disease: sometimes determinant and frequently implicated PMC9604348__F10 Transcriptomic and Physiological Analyses Reveal Potential Genes Involved in Photoperiod-Regulated Beta-Carotene Accumulation Mechanisms in the Endocarp of Cucumber (Cucumis sativus L.) Fruit ENSG00000101266 PMC4253844__F1 Cholesterol in brain disease: sometimes determinant and frequently implicated ENSG00000116133 ENSG00000172893 ENSG00000119655 ENSG00000113161 ENSG00000141458 PMC5005280__F3 Core Hippo pathway ENSG00000186575 ENSG00000197905 ENSG00000007866 ENSG00000131023 ENSG00000074219 PMC5751143__F1 Induction of PD-L1 by IFNG signaling pathway and microRNAs target the key genes in the pathway ENSG00000198793 ENSG00000125347 PMC7343830__F6 Proposed regulatory mechanisms of blood circulation for hypoxic adaptation in Tibetan chickens ENSG00000064601 ENSG00000101109 ENSG00000123213 ENSG00000118729 ENSG00000130234 ENSG00000198793 ENSG00000167965 ENSG00000133961 ENSG00000182621 ENSG00000160293 ENSG00000213853 ENSG00000159399 PMC8487426__F4 Alcohol use disorder (AUD)-associated miRNA–mRNA regulatory networks in the amygdala (AMY), the caudate nucleus (CN), the cerebellum (CRB), and the hippocampus (HIP) of AUD subjects (the Set 1 sample) ENSG00000148798 ENSG00000170743 ENSG00000137801 PMC8487426__F5 Alcohol use disorder (AUD)-associated miRNA–mRNA regulatory networks in the nucleus accumbens (NAc), the prefrontal cortex (PFC), the putamen (PUT), and the ventral tegmental area (VTA) of AUD subjects (the Set 1 sample) ENSG00000015285 PMC8323660__F2 Epigenetic Changes in the Progression of Alcoholic Steatohepatitis ENSG00000188786 ENSG00000100344 ENSG00000143222 ENSG00000120686 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000176125 PMC8381650__F5 NFKB: At the Borders of Autoimmunity and Inflammation ENSG00000160224 ENSG00000137077 ENSG00000137265 ENSG00000171791 ENSG00000049768 ENSG00000026103 PMC8381650__F4 NFKB: At the Borders of Autoimmunity and Inflammation ENSG00000291603 ENSG00000167207 ENSG00000102871 ENSG00000186716 ENSG00000082512 ENSG00000172936 ENSG00000166278 ENSG00000154124 ENSG00000175104 ENSG00000127191 ENSG00000184216 ENSG00000198286 PMC3560853__F3 Scheme showing the potential molecular events induced in cancer cells in the hypoxic tumour microenvironment ENSG00000134086 ENSG00000198793 ENSG00000136997 ENSG00000171791 ENSG00000118777 ENSG00000121966 PMC8476812__F6 Targeting Histone Modifications in Breast Cancer: A Precise Weapon on the Way ENSG00000087245 ENSG00000125740 ENSG00000137673 ENSG00000148400 ENSG00000020633 ENSG00000124766 ENSG00000127528 ENSG00000196470 ENSG00000121966 ENSG00000100290 ENSG00000129757 ENSG00000136997 ENSG00000132326 ENSG00000051180 ENSG00000196208 PMC5562928__F2 Amino acid degradation in I ENSG00000125166 ENSG00000291958 ENSG00000198855 ENSG00000139531 ENSG00000100577 ENSG00000084110 ENSG00000100033 ENSG00000145020 ENSG00000183077 ENSG00000091140 ENSG00000178445 ENSG00000115419 PMC9598921__F4 Chromosome-Level Assembly of Male Opsariichthys bidens Genome Provides Insights into the Regulation of the GnRH Signaling Pathway and Genome Evolution ENSG00000087245 ENSG00000070831 PMC5562928__F1 Amino acid synthesis in I ENSG00000113492 ENSG00000092621 ENSG00000171759 ENSG00000166183 ENSG00000135069 ENSG00000116761 PMC9133560__F4 Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles ENSG00000170365 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000164690 PMC7417299__F5 Chemokine signaling pathway from KEGG has the highest counts for selected feature genes ENSG00000169291 ENSG00000002330 PMC2585609__F1 A schematic representation of the functional domains of Stim and Orai proteins ENSG00000175938 ENSG00000293604 ENSG00000109689 PMC6772062__F1 Canonical Wnt/B‐catenin and divergent signaling pathways ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000105723 PMC7765110__F9 The proposed pathways by which melatonin regulates testosterone production and protects the testicular tissue from oxidative damage in LPS-induced sheep orchitis ENSG00000168066 ENSG00000125538 ENSG00000136869 PMC3942726__F1 Simplified schematic diagram of the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway and proposed cellular regulation of muscle protein synthesis in response to hypoxia, caloric restriction, insulin, muscle contraction, and leucine ENSG00000167658 PMC4491883__F1 NetworkPainter enables researchers to quickly draw publication quality signaling diagrams ENSG00000095585 ENSG00000291603 ENSG00000186716 ENSG00000198793 ENSG00000010671 PMC8021759__F1 Methods to circumvent antiviral immunity ENSG00000213928 ENSG00000139187 PMC4830836__F1 Notch canonical and non-canonical signaling ENSG00000100811 ENSG00000168036 PMC8955653__F2 An Expanding Toolkit for Heterochromatin Repair Studies ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000105486 ENSG00000138346 ENSG00000197299 ENSG00000051180 ENSG00000139618 PMC8535589__F1 Cell Death and Survival Pathways Involving ATM Protein Kinase ENSG00000149311 ENSG00000026103 PMC6386894__F3 cAMP regulates immune response of astrocytes ENSG00000108691 ENSG00000162692 PMC10952836__F1 Signaling pathways involved in ferroptosis regulation ENSG00000168003 ENSG00000151012 ENSG00000196839 ENSG00000167468 ENSG00000111684 ENSG00000115107 ENSG00000074219 PMC8624829__F4 Cucumis sativus L. Seeds Ameliorate Muscular Spasm-Induced Gastrointestinal and Respiratory Disorders by Simultaneously Inhibiting Calcium Mediated Signaling Pathway ENSG00000277571 ENSG00000291971 ENSG00000166501 ENSG00000087085 ENSG00000162924 ENSG00000001626 ENSG00000151617 ENSG00000121879 ENSG00000124181 ENSG00000007171 ENSG00000132170 PMC6915518__F3 Molecular mechanisms of pro- and anti-inflammatory effects of NPs on MФs ENSG00000162711 ENSG00000111537 ENSG00000125538 ENSG00000136869 ENSG00000164342 ENSG00000213523 PMC7760557__F10 Melatonin in mitochondria of NLRP3−/− mice during cardiac aging ENSG00000162711 ENSG00000116688 ENSG00000168040 ENSG00000145020 ENSG00000079999 PMC120784__F11 Upper part of the glycolytic pathway and pathways for production of glycerol, trehalose, and glycogen, with all proteins and their isoforms indicated PMC7236196__F7 Combined proteomics and metabolomics pathway network map of significantly altered metabolites and proteins in ERG-positive prostate cancer compared to ERG-negative prostate cancer ENSG00000157554 ENSG00000151726 ENSG00000173599 ENSG00000198931 ENSG00000113790 PMC9043600__F1 Long Non Coding RNA Based Regulation of Cerebrovascular Endothelium ENSG00000083290 ENSG00000149269 ENSG00000171791 ENSG00000253352 ENSG00000112715 ENSG00000168610 PMC6626573__F6 Targeting of lung cancer stem cell self-renewal pathway by a small molecule Verrucarin J ENSG00000134982 ENSG00000168036 PMC8624829__F5 Cucumis sativus L. Seeds Ameliorate Muscular Spasm-Induced Gastrointestinal and Respiratory Disorders by Simultaneously Inhibiting Calcium Mediated Signaling Pathway ENSG00000124102 ENSG00000182533 ENSG00000291507 ENSG00000130528 ENSG00000179091 ENSG00000156026 ENSG00000186716 ENSG00000087085 ENSG00000166278 ENSG00000198125 ENSG00000115718 ENSG00000127948 PMC8026084__F9 IKAROS is required for the measured response of NOTCH target genes upon external NOTCH signaling ENSG00000104885 ENSG00000111642 PMC7873355__F3 Interaction network showing the mutual involvement of DEPs from SACS KO model and ARSACS patients in Engulfment of Cells (A) and Synaptogenesis Signaling Pathway (B) ENSG00000125266 ENSG00000179094 ENSG00000198125 ENSG00000133216 PMC4397846__F1 Pathway on the left is that of an active cell ENSG00000134982 ENSG00000168036 PMC5819688__F6 Anacardic acid and signaling pathways ENSG00000149311 ENSG00000131165 ENSG00000164949 PMC6658002__F3 Other stimuli leading to necroptosis ENSG00000136869 ENSG00000168040 ENSG00000168404 ENSG00000164342 PMC4681826__F1 Signaling pathways activated by BCR-ABL ENSG00000033327 ENSG00000002330 ENSG00000110395 ENSG00000099942 PMC6658002__F2 TNFR1-mediated signaling pathways ENSG00000102871 ENSG00000082512 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 PMC8851069__F4 Advances in cGAS-STING Signaling Pathway and Diseases ENSG00000164430 PMC6594827__F2 Other fatty acid metabolism targets ENSG00000161533 ENSG00000169710 ENSG00000136826 PMC8851069__F3 Advances in cGAS-STING Signaling Pathway and Diseases ENSG00000162711 ENSG00000164430 PMC8851069__F2 Advances in cGAS-STING Signaling Pathway and Diseases ENSG00000239732 ENSG00000164430 ENSG00000172936 PMC3529804__F3 Novel Directions for Diabetes Mellitus Drug Discovery ENSG00000198793 ENSG00000096717 PMC6880770__F6 Twenty Novel Disease Group-Specific and 12 New Shared Macrophage Pathways ENSG00000131473 ENSG00000069482 ENSG00000065526 ENSG00000148798 ENSG00000115361 ENSG00000167508 PMC9590394__F1 T cell dysregulation in inflammatory diseases in ICU ENSG00000132906 ENSG00000089692 ENSG00000163599 ENSG00000168685 PMC10545798__F1 Landscape of cholesterol homeostasis regulation ENSG00000130164 ENSG00000113161 ENSG00000160179 ENSG00000075239 PMC8716846__F6 Network Pharmacology-Based Investigation and Experimental Exploration of the Antiapoptotic Mechanism of Colchicine on Myocardial Ischemia Reperfusion Injury ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000002330 ENSG00000069482 ENSG00000186716 ENSG00000136997 ENSG00000104894 PMC10545798__F6 Internal and external factor regulation of cholesterol metabolism ENSG00000284495 ENSG00000130164 ENSG00000198793 ENSG00000113161 ENSG00000160179 ENSG00000169174 PMC6372590__F5 PAK4 signaling in health and disease: defining the PAK4–CREB axis ENSG00000134982 ENSG00000168036 PMC10545798__F8 Cholesterol affects tumor cells by modulating immune responses, ferroptosis, tumor cell stemness, and the DNA damage response ENSG00000160752 ENSG00000135218 ENSG00000167468 ENSG00000197429 ENSG00000113161 ENSG00000111684 ENSG00000168610 PMC4447120__F1 AMPK is a negative regulator of the Warburg effect in Fumarate hydratase-deficient kidney cancer ENSG00000079999 PMC3852103__F2 Most significant GeneGO pathway map ENSG00000140992 ENSG00000084676 ENSG00000138798 ENSG00000169047 ENSG00000160182 ENSG00000146648 PMC3213160__F3 Capture of MicroRNA–Bound mRNAs Identifies the Tumor Suppressor miR-34a as a Regulator of Growth Factor Signaling ENSG00000149311 ENSG00000186716 ENSG00000164399 ENSG00000104432 ENSG00000146648 ENSG00000113525 PMC3151497__F3 MAPK signaling pathway ENSG00000087095 ENSG00000172680 ENSG00000113456 ENSG00000075142 ENSG00000170458 ENSG00000130522 ENSG00000138798 ENSG00000136997 ENSG00000146648 ENSG00000117322 ENSG00000026103 PMC10286592__F3 Alteration of mTOR signalling pathway post TBI ENSG00000177169 ENSG00000198793 PMC4411872__F5 Genes involved in GPCR signaling Pathway: (G protein coupled-receptors are seven-transmemebrane receptors involved in signal transduction in humans) ENSG00000105329 ENSG00000112715 PMC10286592__F1 How TBI altered calcium dependent PLC pathways, oxygen species scavenging system and p53 signalling ENSG00000189403 ENSG00000172936 PMC4411872__F7 Genes involved in chronic kidney failure (Disease Pathway) ENSG00000070915 ENSG00000197594 ENSG00000143839 ENSG00000146678 ENSG00000121807 PMC4795462__F2 New Strategies in Renal Cell Carcinoma: Targeting the Genetic and Metabolic Basis of Disease ENSG00000131473 ENSG00000115419 ENSG00000026103 PMC4795462__F1 New Strategies in Renal Cell Carcinoma: Targeting the Genetic and Metabolic Basis of Disease ENSG00000131473 ENSG00000163930 ENSG00000163939 ENSG00000181555 ENSG00000159399 ENSG00000026103 PMC7456827__F1 Circadian regulation of complement immune system ENSG00000165030 ENSG00000105516 ENSG00000132326 ENSG00000166278 ENSG00000069667 PMC9511957__F6 Toll-like receptor 2 signaling pathway activation contributes to a highly efficient inflammatory response in Japanese encephalitis virus-infected mouse microglial cells by proteomics ENSG00000172936 ENSG00000175104 PMC4200202__F7 Simplified interaction map between the LOXL4 protein with the OS pathway by both protein-protein interaction analysis and literature mining ENSG00000139219 ENSG00000008710 ENSG00000101945 ENSG00000138131 ENSG00000105329 ENSG00000138190 ENSG00000105401 ENSG00000163453 ENSG00000130159 ENSG00000096717 ENSG00000106459 PMC8357146__F7 Regulatory mechanism of ASPN and DCN: We have proposed a Schematic illustration of the mechanism based on our conclusion PMC2829627__F3 PPARG agonists inhibit Stat3-mediated IL-6 gene expression in myeloma cells ENSG00000168610 PMC2829627__F2 Tumor-associated angiogenesis is sustained through stromal microenvironment crosstalk ENSG00000019991 PMC316768__F1 Model of somatic sex determination in C ENSG00000115884 ENSG00000162512 ENSG00000169439 PMC6621453__F3 siRNA screening identifies TrkB, TrkC, and FGFR1 ENSG00000157540 ENSG00000198793 ENSG00000077782 PMC9488581__F1 Antineutrophil cytoplasmic antibody-associated interstitial lung disease: a review ENSG00000164362 ENSG00000005381 ENSG00000117983 PMC8949863__F3 Tug of War: Pseudorabies Virus and Host Antiviral Innate Immunity ENSG00000213928 ENSG00000187608 ENSG00000105397 ENSG00000135114 ENSG00000172183 PMC8949863__F2 Tug of War: Pseudorabies Virus and Host Antiviral Innate Immunity ENSG00000164430 ENSG00000276561 PMC8038663__F1 Chemical structure and mammalian glycosphingolipid (GSL) biosynthetic pathway ENSG00000176597 ENSG00000135454 ENSG00000111728 ENSG00000158470 ENSG00000115525 ENSG00000148154 ENSG00000174607 PMC2956880__F4 Schematic diagram showing the interaction of the p75NTR and TrkB signaling pathways ENSG00000002330 ENSG00000132478 ENSG00000120868 PMC9266652__F3 Therapeutic Potential of Allicin and Aged Garlic Extract in Alzheimer’s Disease ENSG00000182809 ENSG00000162711 ENSG00000167207 ENSG00000125538 ENSG00000172936 PMC3822826__F2 Canonical Wnt/Beta-catenin signalling pathway ENSG00000134982 ENSG00000168036 ENSG00000196628 ENSG00000125084 PMC3494605__F1 A role for vimentin in Crohn disease ENSG00000167207 ENSG00000109320 PMC5000717__F2 The Hippo/YAP pathway is physiologically initiated via GPCRs ENSG00000150457 ENSG00000131023 PMC4024337__F4 NFKB gene signature predicts prostate cancer progression ENSG00000180210 ENSG00000141480 ENSG00000134057 ENSG00000291971 ENSG00000167461 ENSG00000113161 ENSG00000137825 ENSG00000104447 ENSG00000130513 ENSG00000158125 PMC5919979__F4 Proliferation-associated lncRNAs act on at specific functional sites of the Wnt signaling pathway ENSG00000165119 ENSG00000137673 ENSG00000168036 PMC5919979__F2 Proliferation-associated lncRNAs act as p53 regulators or effectors by activating or inhibiting the p53 signaling pathway PMC5962695__F1 Extracellular matrix (ECM) in structural and functional synaptic plasticity ENSG00000087245 ENSG00000149968 ENSG00000113140 ENSG00000173599 ENSG00000173406 PMC5919979__F5 Proliferation-associated lncRNAs act as MYC regulators or effectors by activating or inhibiting the MYC signaling pathway ENSG00000198793 ENSG00000136997 ENSG00000168036 PMC3351275__F3 Negative feedback and adaptive resistance to the targeted therapy of cancer ENSG00000198793 PMC8851069__F6 Advances in cGAS-STING Signaling Pathway and Diseases ENSG00000164430 ENSG00000105612 PMC6773825__F2 Main strategies of immunomodulation ENSG00000139193 ENSG00000198793 ENSG00000126353 PMC9569803__F19 Glucogallin Attenuates the LPS-Induced Signaling in Macrophages and Protects Mice against Sepsis ENSG00000162711 ENSG00000173039 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000026103 PMC3457170__F4 JAK/STAT signaling pathway is targeted by RVFV NSs protein at different levels ENSG00000180182 ENSG00000213928 ENSG00000228083 ENSG00000128829 ENSG00000135828 ENSG00000138834 PMC6487307__F12 Schematic summarizing the “reprogramming” of polyamine metabolism by iron-depletion in: (A) SK-Mel-28 human melanoma and (B) MCF-7 human breast cancer cells ENSG00000168003 ENSG00000088826 ENSG00000148832 ENSG00000105656 ENSG00000123505 ENSG00000182551 ENSG00000116649 ENSG00000102172 PMC5134922__F4 Ingenuity Pathway Analysis of the top overlapping networks in chronic beryllium disease and sarcoidosis ENSG00000134460 ENSG00000120833 ENSG00000125384 ENSG00000114737 ENSG00000033800 ENSG00000125347 PMC3221743__F5 Working model describing how in HIV+ macrophages constitutively activated PI3K elicits blunting of lipid A-induced increases in TNFA release through sustained mTOR activation ENSG00000198793 ENSG00000172936 ENSG00000136869 PMC3872233__F4 Toll-like receptor 4 signaling pathway in alcohol consumption ENSG00000172936 ENSG00000136869 ENSG00000184216 PMC9225917__F12 Huangqi Sanxian Decoction Inhibiting Osteoclast Differentiation Based on Network Pharmacology ENSG00000177455 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000136997 ENSG00000136869 PMC6526672__F2 Signalling pathways involved in glucose metabolism‐regulated NLRP3 inflammasome activation ENSG00000162711 ENSG00000283100 PMC8387394__F3 Conservation of epithelial-to-mesenchymal transition process in neural crest cells and metastatic cancer ENSG00000012061 ENSG00000107562 ENSG00000157933 ENSG00000162337 ENSG00000134982 ENSG00000291971 ENSG00000170558 ENSG00000187140 ENSG00000168036 ENSG00000108654 ENSG00000168615 ENSG00000137845 ENSG00000100146 ENSG00000121966 ENSG00000106571 ENSG00000125398 ENSG00000074181 ENSG00000089685 ENSG00000078747 ENSG00000113645 ENSG00000087245 ENSG00000162490 ENSG00000122966 ENSG00000150457 ENSG00000131023 ENSG00000168610 ENSG00000100985 ENSG00000128602 PMC5501640__F1 Sketch of Hedgehog (Hh) signaling pathway ENSG00000106571 ENSG00000144857 ENSG00000128602 PMC8387394__F2 Conservation of epithelial-to-mesenchymal transition process in neural crest cells and metastatic cancer ENSG00000138798 ENSG00000120149 ENSG00000169047 ENSG00000198793 ENSG00000156574 ENSG00000187140 ENSG00000168036 ENSG00000163132 ENSG00000009709 ENSG00000111961 ENSG00000186847 ENSG00000125398 ENSG00000095739 ENSG00000105991 ENSG00000163914 ENSG00000128342 ENSG00000182580 ENSG00000140443 ENSG00000282899 ENSG00000154342 ENSG00000087245 ENSG00000164379 ENSG00000092439 ENSG00000138795 ENSG00000169554 ENSG00000137673 ENSG00000143569 ENSG00000284161 ENSG00000135903 ENSG00000163661 ENSG00000168610 ENSG00000170961 ENSG00000133110 ENSG00000120094 ENSG00000134853 ENSG00000164107 ENSG00000026508 ENSG00000107485 ENSG00000164690 ENSG00000100985 ENSG00000141570 ENSG00000114315 ENSG00000168646 ENSG00000146648 PMC6126134__F1 Nuclear factor KB (NFKB) activation signaling pathways.Canonical NFKB pathway: the canonical pathway is inhibitor of KB (IKB) kinase (IKK)-dependent and IKB-dependent ENSG00000104856 ENSG00000186716 ENSG00000111321 PMC5297776__F3 MTOR signaling pathway as a target of molecular therapies PMC8387394__F5 Conservation of epithelial-to-mesenchymal transition process in neural crest cells and metastatic cancer ENSG00000169554 ENSG00000182568 ENSG00000187140 ENSG00000121807 ENSG00000118971 ENSG00000168610 ENSG00000185104 ENSG00000139219 ENSG00000168283 ENSG00000172292 ENSG00000106571 ENSG00000135446 ENSG00000163993 ENSG00000164690 ENSG00000114315 ENSG00000128602 ENSG00000189299 ENSG00000026103 PMC3213966__F3 Regulation of cardiac hypertrophy by AKAP complexes ENSG00000163914 ENSG00000198626 ENSG00000108840 PMC8387394__F4 Conservation of epithelial-to-mesenchymal transition process in neural crest cells and metastatic cancer ENSG00000094631 ENSG00000104093 ENSG00000105329 ENSG00000187140 ENSG00000168036 ENSG00000150093 ENSG00000151929 ENSG00000171791 ENSG00000187800 ENSG00000168283 ENSG00000125398 ENSG00000156103 ENSG00000283780 ENSG00000152592 ENSG00000125968 ENSG00000087245 ENSG00000106333 ENSG00000259207 ENSG00000120693 ENSG00000113140 ENSG00000168610 ENSG00000197614 ENSG00000162733 ENSG00000128272 ENSG00000167996 ENSG00000133961 ENSG00000100985 PMC6009094__F1 Wnt signalling pathway.Left: the Wnt pathway is activated by the interaction between LRP5/6, Wnt and Frizzled ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC4437511__F4 Proteins from known pathways localized to the Trichomonas vaginalis hydrogensome ENSG00000182511 ENSG00000136003 PMC3437941__F1 Integration of B cell responses through Toll-like receptors and antigen receptors ENSG00000186716 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC7753360__F2 Therapeutic targets and anticancer drugs within the lipid metabolism pathway ENSG00000131473 ENSG00000135218 ENSG00000130164 ENSG00000042832 ENSG00000198793 ENSG00000113161 ENSG00000099194 ENSG00000026103 PMC7753360__F1 Lipid metabolism overview in normal and cancer cells ENSG00000131473 ENSG00000130164 ENSG00000113161 ENSG00000026103 PMC7847636__F3 Canonical Wnt signaling activates DPAGT1 expression and protein N-glycosylation, leading to extensive N-glycosylation of E-cadherin ENSG00000164932 ENSG00000162337 ENSG00000172269 PMC4894499__F3 Sandwich-Cultured Hepatocytes as a Tool to Study Drug Disposition and Drug-Induced Liver Injury ENSG00000276559 PMC12111946__F3 Research Progress in Medical Biomaterials for Bone Infections ENSG00000186716 ENSG00000198793 ENSG00000136869 PMC8076345__F3 Differentially Expressed Protein Interaction Network ENSG00000110700 ENSG00000100852 ENSG00000011376 ENSG00000174021 ENSG00000118873 ENSG00000127884 ENSG00000089818 ENSG00000154917 ENSG00000112290 ENSG00000179271 ENSG00000179403 ENSG00000018236 ENSG00000139220 ENSG00000014123 ENSG00000247626 ENSG00000092148 ENSG00000110717 ENSG00000100347 ENSG00000122140 ENSG00000138768 ENSG00000214253 ENSG00000145362 ENSG00000143977 ENSG00000151376 ENSG00000125826 ENSG00000198830 ENSG00000164904 ENSG00000130811 ENSG00000100554 ENSG00000121774 ENSG00000274665 ENSG00000165264 ENSG00000166128 ENSG00000063245 ENSG00000104327 ENSG00000154305 ENSG00000175198 ENSG00000198961 ENSG00000090857 ENSG00000113758 ENSG00000060339 ENSG00000151498 ENSG00000198053 ENSG00000131495 ENSG00000070182 ENSG00000291971 ENSG00000054179 ENSG00000239388 ENSG00000165280 ENSG00000151532 ENSG00000136888 ENSG00000138035 ENSG00000104980 ENSG00000180992 ENSG00000126803 ENSG00000149269 ENSG00000234032 ENSG00000291387 ENSG00000158874 ENSG00000170515 ENSG00000126458 ENSG00000106305 ENSG00000247077 ENSG00000089597 ENSG00000125814 ENSG00000168958 ENSG00000132305 ENSG00000179091 ENSG00000116337 ENSG00000107566 ENSG00000105402 ENSG00000149182 ENSG00000131828 ENSG00000006534 ENSG00000065609 ENSG00000100505 ENSG00000167535 ENSG00000106263 ENSG00000155660 ENSG00000099795 ENSG00000083799 ENSG00000139190 ENSG00000130175 ENSG00000108774 ENSG00000082212 ENSG00000090520 ENSG00000087274 PMC7490904__F1 Physiological functions and regulation of the cyclin D-CDK4/6 complex ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC5468232__F12 ARF/p53 pathway ENSG00000149311 ENSG00000175054 ENSG00000136997 ENSG00000112378 ENSG00000164305 PMC5468232__F11 Estrogen signaling pathway ENSG00000169291 PMC6080523__F4 Graphic scheme of pathways shared by genes found in network analysis for progressive motility PMC8615680__F1 Genetic Determinants of Plasma Low-Density Lipoprotein Cholesterol Levels: Monogenicity, Polygenicity, and “Missing” Heritability ENSG00000007944 ENSG00000138075 ENSG00000163956 ENSG00000135100 ENSG00000175003 ENSG00000167910 ENSG00000107798 ENSG00000113161 ENSG00000141458 ENSG00000152700 ENSG00000130164 ENSG00000285343 ENSG00000138823 ENSG00000119655 ENSG00000084734 ENSG00000015520 ENSG00000073734 ENSG00000132855 ENSG00000198670 ENSG00000134243 ENSG00000169174 ENSG00000143921 PMC7922891__F7 Hereditary disorder, metabolic disease, organismal injury and abnormalities network affected in lymphoblastoid cells derived from an SS patient ENSG00000111300 ENSG00000185658 ENSG00000196705 ENSG00000205744 ENSG00000071859 ENSG00000161791 ENSG00000128563 ENSG00000104047 ENSG00000133561 ENSG00000129480 ENSG00000273092 ENSG00000166046 ENSG00000121964 ENSG00000100982 ENSG00000185404 PMC7922891__F6 Graphical summary of human skin fibroblast profiling of SS patients ENSG00000120063 ENSG00000173391 ENSG00000127666 ENSG00000136688 PMC7118069__F1 Major signaling pathways for protective mechanisms against ASD by SF ENSG00000284774 ENSG00000079999 PMC8185703__F1 LZTR1: A promising adaptor of the CUL3 family ENSG00000180210 ENSG00000108061 PMC12009291__F1 Glucose metabolism and lipid metabolism reprogramming in RCC ENSG00000132109 ENSG00000024526 ENSG00000114268 ENSG00000103150 ENSG00000127884 PMC8185703__F2 LZTR1: A promising adaptor of the CUL3 family ENSG00000143622 ENSG00000126458 ENSG00000196712 PMC5911514__F2 Primary Cilia as a Signaling Platform for Control of Energy Metabolism ENSG00000134982 ENSG00000168036 ENSG00000128602 PMC5361837__F4 Examples of functional networks of regulated genes shared by different tissues ENSG00000105852 ENSG00000261832 ENSG00000291929 ENSG00000163923 ENSG00000123240 ENSG00000166199 ENSG00000197746 ENSG00000137491 ENSG00000065320 ENSG00000188846 ENSG00000157593 ENSG00000143436 ENSG00000111737 ENSG00000038382 ENSG00000109861 ENSG00000126247 ENSG00000151914 ENSG00000183605 PMC7718646__F1 miRNA-23a can enhance the metastasis and invasion of OS cells by upregulating the signal expression of PTEN signaling pathway ENSG00000002330 ENSG00000164169 ENSG00000138798 ENSG00000198793 ENSG00000183579 ENSG00000146648 PMC8531546__F2 Sphingolipids in Lung Pathology in the Coronavirus Disease Era: A Review of Sphingolipid Involvement in the Pathogenesis of Lung Damage PMC11263586__F5 HPV perturbs DNA damage response signalling pathway ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000276618 ENSG00000051180 PMC2699967__F2 Signaling pathways initiated by TLR-2 and TLR-4 activation ENSG00000183735 ENSG00000170458 ENSG00000172005 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC6349186__F4 Wnt signalling pathway uniquely identified by ce‐Subpathway ENSG00000087095 ENSG00000138795 ENSG00000095739 ENSG00000179091 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000196470 ENSG00000072803 PMC6349186__F5 MI‐related subpathways where key nodes are annotated ENSG00000169291 ENSG00000002330 ENSG00000070831 ENSG00000291971 ENSG00000169047 PMC4094786__F4 Metabolic pathways for the production of the high-value products by using Z ENSG00000143252 PMC3647990__F9 Model for Rrp1 regulation of chitobiose metabolism in B ENSG00000160214 ENSG00000172005 PMC4659440__F5 c-Met as a Target for Personalized Therapy ENSG00000019991 ENSG00000138798 ENSG00000198793 ENSG00000128564 ENSG00000146648 PMC4659440__F3 HGF-MET signaling pathway with its downstream effector components (MAPK, STAT, PI3K-AKT cascades and NFKB) leading to increases in cell survival, motility and proliferation ENSG00000019991 ENSG00000002330 ENSG00000198793 ENSG00000171791 PMC9267302__F6 Investigation of the Molecular Mechanisms Underlying the Antiatherogenic Actions of Kaempferol in Human THP-1 Macrophages ENSG00000175206 ENSG00000177606 ENSG00000065559 ENSG00000141052 ENSG00000128342 ENSG00000166484 ENSG00000121879 ENSG00000135341 ENSG00000073756 ENSG00000184304 ENSG00000087460 ENSG00000120937 PMC6824625__F9 Hypothetical schematic model for a novel oncogenic mechanism of G0S2 ENSG00000087245 ENSG00000291971 ENSG00000168036 ENSG00000100985 ENSG00000131023 ENSG00000123689 PMC3346111__F7 Overall scheme of hypothetical effect of endocannabinoid signaling in human melanocytes ENSG00000115138 ENSG00000196689 PMC4828651__F4 Transcriptome Variability in Keratocystic Odontogenic Tumor Suggests Distinct Molecular Subtypes ENSG00000164161 ENSG00000141480 ENSG00000164690 PMC9679292__F3 New insights in ferroptosis: Potential therapeutic targets for the treatment of ischemic stroke ENSG00000128272 ENSG00000151012 ENSG00000178573 ENSG00000196839 ENSG00000167468 ENSG00000111684 ENSG00000152592 ENSG00000115107 PMC5423227__F1 Alterations in DNA methylation patterns as a source of cancer progression traits ENSG00000134086 ENSG00000134853 ENSG00000171791 ENSG00000112715 ENSG00000115165 ENSG00000102974 PMC9679292__F2 New insights in ferroptosis: Potential therapeutic targets for the treatment of ischemic stroke ENSG00000196839 ENSG00000167468 ENSG00000111684 ENSG00000116761 ENSG00000115419 PMC3944322__F1 Parkinson's Disease Gene Therapy: Success by Design Meets Failure by Efficacy ENSG00000171119 PMC5827560__F1 A biological pathway regulating memory, synaptic plasticity and schizophrenia risk ENSG00000198576 ENSG00000166886 ENSG00000178568 PMC6567807__F1 Curcumin modulates cancer progression by controlling diverse signal transduction pathways ENSG00000002330 ENSG00000198793 ENSG00000168036 ENSG00000132478 ENSG00000168610 PMC3328216__F1 CCM3 interacts with multiple signaling complexes ENSG00000132478 ENSG00000067900 PMC7464343__F2 The mechanisms and cell fate decisions’ crosstalk underlying necroptosis induction ENSG00000137275 ENSG00000102871 ENSG00000082512 ENSG00000132478 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC5593197__F6 Equilibrium between antagonistic signaling pathways determines the number of synapses in Drosophila ENSG00000170365 ENSG00000006451 ENSG00000177606 PMC8075731__F7 HGF/c-Met signaling regulates early differentiation of placental trophoblast cells ENSG00000019991 PMC7761504__F1 Wnt signalling pathways ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000100592 ENSG00000134982 ENSG00000177606 ENSG00000168036 PMC11432004__F4 PI3K/Akt/mTOR signaling pathway by O-GlcNAcylation ENSG00000147162 ENSG00000169047 ENSG00000169710 PMC11432004__F3 Pathways associated with O-GlcNAcylation, thrombosis, inflammation, and cancer ENSG00000122025 ENSG00000019991 ENSG00000049130 ENSG00000163235 ENSG00000135446 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8860906__F1 Helicobacter pylori-Mediated Oxidative Stress and Gastric Diseases: A Review ENSG00000168036 ENSG00000105402 ENSG00000128602 ENSG00000145782 ENSG00000184481 PMC7379337__F7 Schematic illustrating the mechanisms involved in the protection of hyperoside against oxidative liver stress ENSG00000010810 ENSG00000040199 PMC3956533__F7 Resveratrol prevents rapamycin-induced upregulation of autophagy and selectively induces apoptosis in TSC2-deficient cells PMC6909929__F1 Proposed model of myostatin-induced skeletal muscle wasting and insulin resistanceMyostatin binds to it’s receptor (ActR2B), phosphorylating the Smad2/3 pathway ENSG00000169047 ENSG00000198793 PMC5064167__F1 Upstream and downstream mechanisms of the ERK5 signaling cascade in DRG neuronsDashed lines indicate the need for further examination of possible signaling or the mechanism, which is complicated and abbreviated in this text ENSG00000291971 ENSG00000081189 PMC3059306__F1 TSC mediated signaling in the central nervous system ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC6548990__F2 TNFR1 signaling ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000064012 ENSG00000285379 PMC6548990__F4 Cytotoxic TLR-TNF signaling network ENSG00000137275 ENSG00000173039 ENSG00000168040 ENSG00000127191 ENSG00000125538 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000083799 ENSG00000168404 ENSG00000064012 ENSG00000285379 ENSG00000164342 PMC6548990__F3 TNFR2 signaling ENSG00000056558 ENSG00000131323 PMC6548990__F5 Type I interferons in the cytotoxic TLR-TNF signaling network ENSG00000213928 ENSG00000137275 ENSG00000173039 ENSG00000125347 ENSG00000142166 ENSG00000183735 ENSG00000105397 ENSG00000115415 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000168404 ENSG00000285379 ENSG00000164342 PMC8377849__F10 Pitx controls amphioxus asymmetric morphogenesis by promoting left-side development and repressing right-side formation ENSG00000274382 ENSG00000156574 PMC3133224__F9 Molecular interplay between FBXL2, its substrate CCTA, and CaM controls phosphatidylcholine (PC) synthesis ENSG00000150991 ENSG00000113558 PMC6787465__F1 Schematic outline of major Btk signalling cascades ENSG00000177455 ENSG00000095585 ENSG00000162711 ENSG00000100290 ENSG00000186716 ENSG00000172005 ENSG00000197943 ENSG00000172936 ENSG00000175104 ENSG00000010671 ENSG00000164342 PMC5063375__F4 Fuzzy Decision Making Approach to Identify Optimum Enzyme Targets and Drug Dosage for Remedying Presynaptic Dopamine Deficiency PMC9623986__F3 Personalized targeted therapy prescription in colorectal cancer using algorithmic analysis of RNA sequencing data ENSG00000130939 ENSG00000083093 ENSG00000157764 ENSG00000163743 ENSG00000169032 ENSG00000145386 ENSG00000166851 ENSG00000139618 ENSG00000068028 ENSG00000127445 ENSG00000078900 ENSG00000078747 ENSG00000123374 ENSG00000100784 ENSG00000173846 ENSG00000149554 ENSG00000175305 PMC3494587__F12 Depletion of L-arginine induces autophagy as a cytoprotective response to endoplasmic reticulum stress in human T lymphocytes ENSG00000124102 ENSG00000134109 ENSG00000128272 ENSG00000128829 ENSG00000100219 ENSG00000171791 ENSG00000145782 PMC4332478__F3 Integrative Multi-omics Module Network Inference with Lemon-Tree ENSG00000171105 ENSG00000135446 ENSG00000134853 ENSG00000283059 ENSG00000146648 ENSG00000139687 ENSG00000198625 PMC7388972__F5 Schematic representation of S. pombe cell wall integrity pathway ENSG00000124253 ENSG00000123268 PMC6129528__F4 Regulation of cell signaling pathways involved in cancers by KDM2B ENSG00000198793 ENSG00000168036 PMC6129528__F6 Overview of KDM2B mediated molecular mechanisms in cancer development ENSG00000170091 ENSG00000073614 ENSG00000136997 PMC10898159__F3 Mechanism of action of existing drugs targeting KIT expression and mutations ENSG00000141867 ENSG00000157404 ENSG00000110395 ENSG00000117425 ENSG00000185591 ENSG00000277273 ENSG00000128602 ENSG00000133805 PMC4145906__F3 The role of mitochondria in Parkinson's disease PMC7513951__F3 MUC1-C in chronic inflammation and carcinogenesis; emergence as a target for cancer treatment ENSG00000136997 ENSG00000196628 PMC5596544__F8 Schematic of the AcSDKP/FGFR1/MAP4K4 pathway suppression of TGFB/smad signaling and EndMT ENSG00000077782 PMC9338018__F1 MiR-30a-centered molecular crosstalk regulates Th17 differentiation ENSG00000109452 ENSG00000173039 ENSG00000136869 ENSG00000103522 PMC7513951__F2 MUC1-C in chronic inflammation and carcinogenesis; emergence as a target for cancer treatment ENSG00000291971 ENSG00000198793 ENSG00000146648 PMC11641392__F2 Notch signaling pathway with Notch and Bcl-2 therapeutic targets in T-ALL ENSG00000140564 ENSG00000002330 ENSG00000140379 ENSG00000159335 ENSG00000137845 PMC7158685__F1 Main immunological pathways in human antigen presenting cells (APCs) after mycobacterial RNA recognition ENSG00000111537 ENSG00000134982 ENSG00000125538 ENSG00000172936 ENSG00000164342 PMC4052302__F10 General overview of TLR4 signaling in humans ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 PMC4300671__F1 Working model for rotavirus cell entry into MA104 cells ENSG00000003056 ENSG00000102189 ENSG00000070831 ENSG00000130402 PMC5796392__F6 Role of miRNA in the antigen cross presentation pathway ENSG00000115415 ENSG00000205220 ENSG00000230034 PMC11223907__F1 Cyclophosphamide Pharmacogenomic Variation in Cancer Treatment and Its Effect on Bioactivation and Pharmacokinetics ENSG00000165841 PMC5613881__F2 Regulation and signaling crosstalk of the Hippo pathway ENSG00000134982 ENSG00000163914 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC10898159__F2 Regulations in KIT protein and signaling pathway ENSG00000145721 ENSG00000157404 ENSG00000142235 ENSG00000117425 ENSG00000128602 ENSG00000133805 PMC10898159__F1 Gene and epigenetic regulations of KIT expression in GIST ENSG00000141867 ENSG00000157404 ENSG00000113196 ENSG00000089685 ENSG00000103241 ENSG00000102974 PMC3430207__F3 Molecular relational network of genes modulated by BaP in lung tissues enriched for cancer function using IPA for all three doses with p53 at the central node ENSG00000145632 ENSG00000283887 ENSG00000140092 ENSG00000124762 ENSG00000095585 ENSG00000274619 ENSG00000213949 ENSG00000288411 ENSG00000117525 ENSG00000049130 ENSG00000011422 ENSG00000115457 ENSG00000149968 ENSG00000136997 ENSG00000125538 ENSG00000164938 ENSG00000163017 ENSG00000006327 ENSG00000121053 ENSG00000106178 ENSG00000130513 ENSG00000027075 ENSG00000148346 ENSG00000142627 ENSG00000091972 ENSG00000173039 ENSG00000091879 ENSG00000284984 ENSG00000140416 ENSG00000115602 ENSG00000113328 ENSG00000138193 ENSG00000170962 ENSG00000167325 ENSG00000134853 ENSG00000135363 ENSG00000112378 ENSG00000164690 ENSG00000115461 PMC5613881__F1 A brief summary of the intracellular Hippo pathway in mammals ENSG00000150457 ENSG00000131023 PMC8909069__F3 Biomarkers in FLT3 AML ENSG00000198793 PMC6952906__F2 Schemes of feedforward loops (FFLs) ENSG00000116521 ENSG00000139687 ENSG00000132170 PMC7395767__F1 Old dogs, new trick: classic cancer therapies activate cGAS ENSG00000183735 ENSG00000164430 PMC6462526__F6 5′-IT treatment affects intra-/extracellular adenosine balance and INSM1 expression leading to NB tumor cell death ENSG00000173404 ENSG00000156110 ENSG00000196839 ENSG00000168036 PMC4556939__F4 Transcriptomic analysis of cyclic AMP response in bovine cumulus cells ENSG00000152661 ENSG00000170027 ENSG00000112715 ENSG00000163661 ENSG00000168610 ENSG00000124762 ENSG00000007171 ENSG00000104368 ENSG00000066468 ENSG00000170961 ENSG00000130164 ENSG00000082175 ENSG00000038427 ENSG00000134853 ENSG00000100985 ENSG00000077782 ENSG00000124253 ENSG00000127616 PMC4556939__F7 Proposed pathway of cAMP signaling after FID addition during in vitro maturation ENSG00000170961 ENSG00000109321 ENSG00000146648 ENSG00000159399 PMC5503519__F9 Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells ENSG00000112576 ENSG00000107485 ENSG00000131724 PMC9573978__F2 Emerging roles for IL-25 and IL-33 in colorectal cancer tumorigenesis ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4199747__F6 PIAS3 activates the intrinsic apoptotic pathway in non-small cell lung cancer cells independent of p53 status ENSG00000187288 ENSG00000168610 PMC3547332__F5 MicroRNA involvement in the inflammation, innate immunity, and oxidative stress pathways in AD and cancer ENSG00000134070 ENSG00000000971 ENSG00000175104 ENSG00000184216 PMC3481480__F11 Pathway Diagram of Oxidative Stress along with PI3k/Akt ENSG00000149311 ENSG00000002330 ENSG00000178573 ENSG00000156273 ENSG00000079999 PMC8255023__F4 Aberrantly methylated-differentially genes and pathways among Iranian patients with colorectal cancer ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000095739 ENSG00000134982 ENSG00000167941 ENSG00000113558 ENSG00000148175 ENSG00000185269 PMC6354055__F1 Mutation Hotspots in the Beta-Catenin Gene: Lessons from the Human Cancer Genome Databases ENSG00000138795 ENSG00000134982 ENSG00000168036 PMC9550596__F5 Henipaviruses: an expanding global public health concern? ENSG00000088888 ENSG00000115415 ENSG00000121060 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC6305535__F5 Representation illustrating the interactions of Fusobacterium nucleatum in colorectal cancer ENSG00000125538 ENSG00000168036 ENSG00000172936 ENSG00000136869 PMC4687939__F6 Comparative Analysis of Muscle Transcriptome between Pig Genotypes Identifies Genes and Regulatory Mechanisms Associated to Growth, Fatness and Metabolism ENSG00000166819 ENSG00000178860 ENSG00000168000 ENSG00000122877 ENSG00000168036 ENSG00000265972 ENSG00000175029 ENSG00000109787 ENSG00000057663 ENSG00000176692 ENSG00000125398 ENSG00000172216 ENSG00000143379 ENSG00000134324 ENSG00000132326 ENSG00000100219 ENSG00000285485 ENSG00000114115 ENSG00000109670 PMC7092482__F1 Epigenetic modulation of noncoding RNAs regulate cancer biology ENSG00000091542 ENSG00000146648 ENSG00000123908 PMC8817562__F1 Designing strategies of small-molecule compounds for modulating non-coding RNAs in cancer therapy ENSG00000134982 ENSG00000168036 ENSG00000168610 PMC7590900__F1 CXCR3 signaling pathways in different cell types ENSG00000169248 ENSG00000169245 ENSG00000186810 ENSG00000148798 ENSG00000138755 ENSG00000023697 ENSG00000084774 PMC4267650__F6 The roles of the RuvBL1-RuvBL2 complex in regulating the FA DNA repair pathway ENSG00000149311 ENSG00000175054 ENSG00000198793 ENSG00000157106 ENSG00000175792 ENSG00000196367 PMC6964678__F3 Lipid metabolism by PI3K–mTOR signalling ENSG00000131473 ENSG00000118515 ENSG00000169710 ENSG00000008130 ENSG00000135250 ENSG00000109670 PMC6964678__F2 Cancer cells obtain fatty acids (FAs) from de novo lipogenesis and exogenous uptake ENSG00000131473 ENSG00000135423 ENSG00000135218 ENSG00000134824 ENSG00000099194 ENSG00000026103 PMC3694595__F1 IL-33: A Novel Danger Signal System in Atopic Dermatitis ENSG00000137033 ENSG00000145777 ENSG00000166090 PMC4918232__F2 B cell receptor pathway in chronic lymphocytic leukemia: specific role of CC-292 ENSG00000105369 ENSG00000186716 ENSG00000198793 ENSG00000010671 PMC4918232__F1 Antigenic stimulation of the BCR recruits CD79a and CD79b, and activates SYK and LYN kinase, resulting in the phosphorylation of cytoplasmic ITAMs on the immunoglobulin domains of the receptor ENSG00000186716 ENSG00000198793 ENSG00000277943 ENSG00000010671 PMC4929790__F2A Targeting the Diabetic Chaperome to Improve Peripheral Neuropathy ENSG00000168028 ENSG00000148346 ENSG00000100906 ENSG00000095951 ENSG00000143198 ENSG00000221869 ENSG00000265972 ENSG00000091879 ENSG00000125347 ENSG00000111348 ENSG00000276561 ENSG00000137801 ENSG00000117525 ENSG00000163131 ENSG00000198576 ENSG00000196498 ENSG00000162692 ENSG00000005381 ENSG00000115165 PMC2824626__F1 Pathway for cholesterol synthesis from 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) by HMG CoA reductase and its inhibition by statins ENSG00000070831 PMC5577206__F2 Vascular endothelial growth factor-B in metabolic homoeostasis: current evidence ENSG00000112715 ENSG00000026103 PMC4598984__F1 Data analysis of the identified Snf1 interactors ENSG00000158516 PMC11871796__F2 The possible mechanism leading to Tourette syndrome (TS) associated with the immune response/inflammation ENSG00000168610 PMC11871796__F1 Microglia M1 polarization–mediated tic onset ENSG00000107859 ENSG00000108691 ENSG00000136997 ENSG00000091592 PMC3661948__F2 Receptor-mediated regulation of KATP channels ENSG00000171105 ENSG00000166603 PMC5078009__F4 Matrix stiffness-mediated effects on stemness characteristics occurring in HCC cells ENSG00000119888 ENSG00000198793 PMC12162393__F9 Diagram of potential mechanism of TPX2 in HCC ENSG00000198793 PMC7485276__F2 Illustration of selective components in the BMP signaling pathway, important for bone and cartilage formation and fracture healing ENSG00000170365 PMC4523214__F1 Idelalisib: First-in-Class PI3K Delta Inhibitor for the Treatment of Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia, and Follicular Lymphoma ENSG00000177455 ENSG00000186716 ENSG00000198793 ENSG00000197943 ENSG00000010671 PMC7846844__F8 LincRNAs involvement in muscle fiber hypertrophy signaling by regulating its target genes ENSG00000156026 ENSG00000173599 ENSG00000140443 PMC8946552__F2 Ferric Nitrilotriacetate in Renal Carcinogenesis and Cell Death: From Animal Models to Clinical Implications ENSG00000019991 ENSG00000163930 ENSG00000163939 ENSG00000073578 ENSG00000117118 ENSG00000112561 ENSG00000217128 ENSG00000079999 ENSG00000143252 ENSG00000182511 ENSG00000100387 ENSG00000135446 ENSG00000052795 ENSG00000105810 ENSG00000146648 PMC8946552__F4 Ferric Nitrilotriacetate in Renal Carcinogenesis and Cell Death: From Animal Models to Clinical Implications ENSG00000228716 ENSG00000167468 ENSG00000111684 PMC9214809__F8 Selective PPARD agonist seladelpar suppresses bile acid synthesis by reducing hepatocyte CYP7A1 via the fibroblast growth factor 21 signaling pathway ENSG00000105550 ENSG00000167910 PMC11868049__F2 Downstream effects of the ubiquitination process in the cGAS-STING pathway ENSG00000183735 ENSG00000164430 ENSG00000204977 ENSG00000175104 ENSG00000143258 PMC11868049__F1 Ubiquitination in cellular processes of cGAS-STING Pathway ENSG00000183735 ENSG00000164430 ENSG00000146063 ENSG00000162032 ENSG00000143258 PMC7080318__F7 LINE-1-induced replication stress ENSG00000175054 ENSG00000164053 ENSG00000113456 ENSG00000144554 ENSG00000132646 ENSG00000165392 ENSG00000168411 ENSG00000147231 ENSG00000197299 PMC7352172__F2 Activation of the NMRK2 pathway represent a common adaptive mechanism in the failing heart where NAD+ levels are low ENSG00000077009 ENSG00000105835 PMC7352172__F1 NAD+synthesis pathways ENSG00000105835 ENSG00000123572 PMC8122392__F2 Context-Dependent Impact of Integrin-Associated CD151 and Other Tetraspanins on Cancer Development and Progression: A Class of Versatile Mediators of Cellular Function and Signaling, Tumorigenesis and Metastasis ENSG00000135218 ENSG00000281324 ENSG00000085117 ENSG00000162337 ENSG00000134982 ENSG00000136997 ENSG00000173039 ENSG00000168036 PMC4698020__F8 Schematic diagram showing the inhibitory effects of triptolide on oxaliplatin induced upregulation of nucleotide excision repair pathway ENSG00000012061 ENSG00000136936 PMC5882534__F2 Optogenetically controlled protein kinases for regulation of cellular signaling ENSG00000002330 PMC7418174__F1 Diagram showing mTORC1 and mTORC2 signaling pathways ENSG00000177169 ENSG00000169047 ENSG00000155792 ENSG00000112561 PMC9279477__F2 Calculated excited states of Pd-DPAphos complexes and synthesis of DPAsphox (1) ENSG00000115904 ENSG00000100485 PMC5826840__F8 Myeloid Notch1 Deficiency Activates RhoA/ROCK Pathway And Aggravates Hepatocellular Damage In Mouse Ischemic Livers ENSG00000148400 ENSG00000132478 ENSG00000172936 ENSG00000136869 ENSG00000067900 ENSG00000114315 ENSG00000175104 ENSG00000164305 PMC11694134__F4 RAS pathway activation and downstream effects in chronic myelomonocytic leukemia ENSG00000110395 ENSG00000135446 ENSG00000115904 ENSG00000087586 ENSG00000105810 ENSG00000166851 ENSG00000100485 ENSG00000196712 ENSG00000179295 PMC11694134__F5 Additional established and investigational therapeutic targets in chronic myelomonocytic leukemia ENSG00000141867 ENSG00000162711 ENSG00000078399 ENSG00000125538 ENSG00000186818 ENSG00000171791 PMC9325157__F2 Coronaviral Infection and Interferon Response: The Virus-Host Arms Race and COVID-19 ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000130234 ENSG00000136869 ENSG00000164342 PMC7555177__F5 Sphingolipid signaling pathway and sphingolipid metabolism ENSG00000033327 ENSG00000070610 ENSG00000105647 ENSG00000088256 ENSG00000169032 ENSG00000285281 ENSG00000035681 ENSG00000100422 ENSG00000170266 ENSG00000067606 ENSG00000147869 ENSG00000010810 ENSG00000163914 ENSG00000170989 ENSG00000213694 ENSG00000078124 ENSG00000168398 ENSG00000125910 ENSG00000148154 PMC7555177__F4 Protein–protein interaction networks of the encoded proteins of the consistent DEGs that participate in sphingolipid signaling pathway (hsa04071) and sphingolipid metabolism (hsa00600) ENSG00000140992 ENSG00000221914 ENSG00000070610 ENSG00000105647 ENSG00000171791 ENSG00000169032 ENSG00000121879 ENSG00000035681 ENSG00000129219 ENSG00000198964 ENSG00000169750 ENSG00000170266 ENSG00000078124 ENSG00000168398 ENSG00000067900 ENSG00000182621 ENSG00000285281 ENSG00000267534 ENSG00000068971 ENSG00000135587 ENSG00000078304 ENSG00000149534 ENSG00000100422 ENSG00000074211 ENSG00000117020 ENSG00000185386 ENSG00000100596 ENSG00000067606 ENSG00000010810 ENSG00000092020 ENSG00000292130 ENSG00000166224 ENSG00000148154 ENSG00000171608 ENSG00000168350 PMC8569372__F6 Alternative splicing in human cancer progression ENSG00000117650 ENSG00000011304 PMC6959052__F7 Working model of the role of IL-6/STAT3 pathway on hypoxia promoting HCC progression after TACE ENSG00000124216 ENSG00000105656 ENSG00000168610 PMC8699390__F3 Of E3 Ubiquitin Ligases in Cancer Immunity: Opportunities and Challenges ENSG00000104856 ENSG00000132109 ENSG00000108395 ENSG00000106785 ENSG00000112343 ENSG00000113595 ENSG00000119401 ENSG00000204977 ENSG00000146833 ENSG00000171206 ENSG00000121236 ENSG00000169871 ENSG00000078747 ENSG00000132256 ENSG00000183718 ENSG00000175104 ENSG00000121060 PMC3656004__F11 Acetylcholine Promotes Ca2+and NO-Oscillations in Adipocytes Implicating Ca2+→NO→cGMP→cADP-ribose→Ca2+ Positive Feedback Loop - Modulatory Effects of Norepinephrine and Atrial Natriuretic Peptide ENSG00000137672 ENSG00000138741 PMC3348393__F1 Cellular Senescence and Cancer Chemotherapy Resistance ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 PMC8621778__F1 Misregulation of Wnt Signaling Pathways at the Plasma Membrane in Brain and Metabolic Diseases ENSG00000281324 ENSG00000162337 ENSG00000100592 ENSG00000134982 ENSG00000173218 ENSG00000168036 PMC9688300__F1 O-GlycNacylation Remission Retards the Progression of Non-Alcoholic Fatty Liver Disease ENSG00000147162 ENSG00000198408 ENSG00000124253 ENSG00000160741 ENSG00000026103 PMC7103590__F8 Expression profiles and prognostic significance of WNT family members in glioma via bioinformatic analysis ENSG00000087095 ENSG00000169291 ENSG00000095739 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000138798 ENSG00000198793 ENSG00000113558 ENSG00000105656 ENSG00000196470 PMC9688300__F3 O-GlycNacylation Remission Retards the Progression of Non-Alcoholic Fatty Liver Disease ENSG00000147162 ENSG00000160181 ENSG00000100219 ENSG00000285379 PMC9688300__F2 O-GlycNacylation Remission Retards the Progression of Non-Alcoholic Fatty Liver Disease ENSG00000169047 PMC2584165__F2 Highly simplified diagram of signaling pathways involving Beta-catenin that may be relevant for RPE cell morphogenesis and susceptibility to age-related oxidative stress ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000170558 ENSG00000168036 ENSG00000107165 PMC8781927__F6 FGFC1 Exhibits Anti-Cancer Activity via Inhibiting NFKB Signaling Pathway in EGFR-Mutant NSCLC Cells ENSG00000135446 PMC7317222__F6 Cholesterol-oxysterol metabolic pathway ENSG00000138135 ENSG00000036530 PMC1297683__F3 Final network resulting from applications of our integration method to the 18 types of evidence for yeast galactose utilization and a set of network analysis tools ENSG00000144063 ENSG00000002549 PMC2746948__F1 Apoptosis pathway ENSG00000120868 ENSG00000168040 ENSG00000026103 PMC6235681__F2 Details of the SHH and Akt pathways ENSG00000198793 ENSG00000164690 ENSG00000128602 ENSG00000177425 PMC3184252__F6 Pathways of androgen biosynthesis ENSG00000135437 ENSG00000086696 ENSG00000151632 PMC6208163__F6 The Roles of NRF2 in Modulating Cellular Iron Homeostasis ENSG00000151012 ENSG00000125144 ENSG00000178573 ENSG00000167468 ENSG00000167996 PMC2212135__F6 Prolactin Receptor Signaling Is Essential for Perinatal Brown Adipocyte Function: A Role for Insulin-like Growth Factor-2 ENSG00000197081 ENSG00000140443 ENSG00000113494 PMC7135884__F3 Metabolic adaptations after phagocytosis and inflammatory stimulation in macrophages and microglia ENSG00000125538 ENSG00000198793 PMC6208163__F2 Roles of NRF2 in Modulating Cellular Iron Homeostasis ENSG00000066926 ENSG00000178573 ENSG00000115657 PMC10779880__F4 Mechanisms of treatment of neurodegenerative diseases (NDs) using capsaicin and N-oleoyldopamin (OLDA) ENSG00000242689 ENSG00000117480 ENSG00000198793 ENSG00000196689 PMC4179759__F1 Melanoma signaling pathway ENSG00000157764 PMC7477441__F7 Mechanism of LINC00355:8 in HCC ENSG00000170558 ENSG00000169884 ENSG00000168036 PMC3797167__F7 Illustration of the proposed mechanisms underlying the crosstalk between insulin/IGF1 and IL-17 signaling pathways ENSG00000163739 ENSG00000082512 ENSG00000175104 ENSG00000127191 ENSG00000115009 ENSG00000163702 PMC6874469__F5 ERB/Ptgds signalling pathway imbalance disrupting renal lipid metabolism and continues influencing ‘hypothalamus-uterus-kidney axis’ (HUK axis) function ENSG00000106927 PMC5419340__F2 Diet supplies nicotinamide, nicotinic acid, and nicotinamide riboside as well as the essential amino acid tryptophan ENSG00000105835 ENSG00000278488 PMC5916231__F1 Heme synthesis pathway ENSG00000110711 ENSG00000066926 ENSG00000080819 ENSG00000256269 ENSG00000188690 PMC6557297__F4 Possible replication-coupled ICL repair mechanisms ENSG00000109674 ENSG00000183763 ENSG00000187790 ENSG00000197299 PMC2600462__F5 Morphoproteomic Evidence of Constitutively Activated and Overexpressed mTOR Pathway in Cervical Squamous Carcinoma and High Grade Squamous Intraepithelial Lesions ENSG00000145604 ENSG00000198793 ENSG00000146648 PMC11615404__F10 Fisetin on ferroptosis and oxidative stress in glutamate- and erastin-stimulated HT22 cells and rats after TBI, which may involve the PI3K/AKT/NRF2 pathway ENSG00000168003 ENSG00000167468 ENSG00000115107 PMC3097389__F1 CoQ10 biosynthesis pathway ENSG00000132423 ENSG00000119723 ENSG00000110871 ENSG00000148459 ENSG00000173085 ENSG00000167186 PMC3497051__F4 Autophagy process ENSG00000177169 ENSG00000152348 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC8570279__F1 Transcriptional Control of Metastasis by Integrated Stress Response Signaling ENSG00000128272 ENSG00000144895 ENSG00000162772 ENSG00000079999 PMC2820251__F1 Innate immune evasion strategies of influenza viruses ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000175104 ENSG00000121060 PMC9252739__F1 Shiny GATOM: omics-based identification of regulated metabolic modules in atom transition networks ENSG00000131473 ENSG00000125166 ENSG00000105835 ENSG00000138030 ENSG00000143198 ENSG00000153574 ENSG00000172340 ENSG00000130653 ENSG00000074800 ENSG00000116353 ENSG00000197594 ENSG00000167325 ENSG00000083720 PMC5095918__F5 LUBAC and UBE2L3 regulate NFKB response ENSG00000125538 ENSG00000185651 PMC7483931__F1 Periodontal disease associated genes and proteins have multiple possible interactions with GM-CSF and TSLP ENSG00000161955 ENSG00000065357 ENSG00000107562 ENSG00000186792 ENSG00000133110 ENSG00000106302 ENSG00000073756 ENSG00000109205 PMC7917312__F2 Armed oHSVs for GBM treatment ENSG00000131019 ENSG00000111537 ENSG00000144895 ENSG00000139187 PMC3445623__F2 Gene Expression and Functional Annotation of the Human Ciliary Body Epithelia ENSG00000171720 ENSG00000082175 ENSG00000291971 ENSG00000146678 ENSG00000131910 ENSG00000155974 ENSG00000141456 PMC4866511__F7 Endosomal System Genetics and Autism Spectrum Disorders: A Literature Review PMC7923825__F1 Engineered (S)-linalool biosynthetic pathway in P ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC6032036__F4 Ingenuity pathway analysis of ALX4 genes and antidepressant genes based on treatment response in MDD ENSG00000138795 ENSG00000007237 ENSG00000167910 ENSG00000130649 ENSG00000168036 ENSG00000122194 ENSG00000102468 ENSG00000151348 ENSG00000186204 ENSG00000052850 ENSG00000155016 ENSG00000129167 ENSG00000136997 PMC7363449__F1 Acute Kidney Injury and Maladaptive Tubular Repair Leading to Renal Fibrosis ENSG00000175054 ENSG00000137275 ENSG00000172936 PMC4673612__F6 Simple feature construction method for predicting upstream/downstream signal flow in human protein-protein interaction networks ENSG00000140992 ENSG00000064490 ENSG00000152661 ENSG00000138798 ENSG00000130522 ENSG00000089159 ENSG00000187800 ENSG00000245848 ENSG00000172216 ENSG00000163558 ENSG00000136997 ENSG00000185591 ENSG00000291608 ENSG00000136158 ENSG00000157764 ENSG00000109320 ENSG00000198561 ENSG00000106299 ENSG00000173039 ENSG00000153317 ENSG00000107295 ENSG00000063245 ENSG00000177189 ENSG00000138193 ENSG00000067606 ENSG00000006451 ENSG00000144118 PMC8870348__F3 Re-Discovery of Pyrimidine Salvage as Target in Cancer Therapy ENSG00000124479 ENSG00000102967 PMC4673612__F4 Simple feature construction method for predicting upstream/downstream signal flow in human protein-protein interaction networks ENSG00000166167 ENSG00000138134 ENSG00000125740 ENSG00000157933 ENSG00000005339 ENSG00000130522 ENSG00000115904 ENSG00000168036 ENSG00000067900 ENSG00000162772 ENSG00000081189 ENSG00000168522 ENSG00000012048 ENSG00000177426 ENSG00000148498 ENSG00000188191 ENSG00000141480 ENSG00000198742 ENSG00000176248 ENSG00000026508 ENSG00000175104 PMC4673612__F7 Simple feature construction method for predicting upstream/downstream signal flow in human protein-protein interaction networks ENSG00000162552 ENSG00000154342 ENSG00000166167 ENSG00000182968 ENSG00000154764 ENSG00000169071 ENSG00000134982 ENSG00000170558 ENSG00000174804 ENSG00000150764 ENSG00000168036 ENSG00000277641 ENSG00000125084 ENSG00000196628 ENSG00000127445 ENSG00000100592 ENSG00000141480 ENSG00000166501 ENSG00000105810 ENSG00000168646 PMC11830176__F1 HBME inhibit LPS activated canonical NF-kB pathway in microglia and its effectors ENSG00000162711 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC4911209__F1 Complete vs ENSG00000169554 PMC5095918__F2 The Fanconi anaemia pathway ENSG00000126218 ENSG00000139618 PMC2820251__F2 Innate immune evasion strategies of influenza viruses ENSG00000187608 ENSG00000105397 ENSG00000115415 PMC3337981__F8 BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NFKB pathway ENSG00000104856 ENSG00000186716 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC5559228__F4 Control of B Lymphocyte Development and Functions by the mTOR Signaling Pathways ENSG00000198793 ENSG00000217128 PMC7554788__F1 Action of CDK4/6 inhibitors ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC5727316__F1 lncRNAs in Wnt/B‐catenin signalling ENSG00000134982 ENSG00000168036 ENSG00000105723 PMC5559228__F2 Control of B Lymphocyte Development and Functions by the mTOR Signaling Pathways ENSG00000177455 ENSG00000177169 ENSG00000198793 ENSG00000052795 ENSG00000164327 ENSG00000217128 ENSG00000010671 PMC4263855__F3 Potential protective role of O-GlcNAcylation within the healthy brain, which may become deficient in the AD brain ENSG00000142192 ENSG00000147162 ENSG00000198408 PMC10304117__F1 ASFV proteins modulating the cGAS/STING and NFKB signaling pathway (Created with BioRender ENSG00000183735 ENSG00000213928 ENSG00000164430 ENSG00000133135 PMC9243614__F3 Differential miRNA expression profiling of highly pathogenic avian influenza virus H5N1 infected chicken lungs reveals critical microRNAs, biological pathways and genes involved in the molecular pathogenesis ENSG00000104365 ENSG00000100906 ENSG00000109320 ENSG00000125538 ENSG00000141753 ENSG00000146678 ENSG00000162924 ENSG00000213341 ENSG00000115461 ENSG00000140443 PMC6415732__F2 Chronic myelogenous leukemia, a still unsolved problem: pitfalls and new therapeutic possibilities ENSG00000149311 ENSG00000177169 ENSG00000123395 ENSG00000254550 PMC5115891__F3 Comprehensive transcriptomic analysis of differentiating embryonic stem cells in response to the overexpression of Mesogenin 1 ENSG00000198793 ENSG00000177606 ENSG00000179111 ENSG00000114315 PMC3797025__F7 Schematic model of adaptive primary resistant responses by tumors to anti–IGF-1R monoclonal antibodies (mAbs) ENSG00000291971 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC3387494__F3 The regulatory network of EZH2 ENSG00000123374 PMC3026729__F7 Defective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in mice ENSG00000121068 ENSG00000138622 ENSG00000285109 ENSG00000006283 ENSG00000089225 PMC11821632__F1 Canonical and non-canonical TGFB signalling pathways ENSG00000198793 ENSG00000175104 ENSG00000135341 ENSG00000076604 PMC8628126__F2 SARS-CoV-2: Emerging Role in the Pathogenesis of Various Thyroid Diseases ENSG00000070831 ENSG00000115415 ENSG00000044115 ENSG00000149269 ENSG00000163914 ENSG00000196591 ENSG00000067900 ENSG00000047849 ENSG00000123268 ENSG00000171533 PMC9353242__F2 Hedgehog signaling regulates the development and treatment of glioblastoma ENSG00000274429 ENSG00000133937 ENSG00000128602 PMC7563227__F2 Roles of PGs in hormone-dependent cancer metastasis ENSG00000115884 ENSG00000281324 ENSG00000291971 ENSG00000168610 ENSG00000115009 ENSG00000062485 PMC4888354__F3 The mechanisms of action of ANG Secreted ANG undergoes receptor-mediated endocytosis from the cell surface to the inside of the cell where it accumulates in the nucleoli under growth conditions or in the cytoplasm under stress conditions ENSG00000188313 ENSG00000134363 PMC5557313__F1 Illustration of the complement activation pathway with annotations for quantified glomerular proteins in progressive versus non-progressive IgAN patients ENSG00000039537 ENSG00000113600 ENSG00000116785 ENSG00000244414 ENSG00000203710 ENSG00000292002 ENSG00000166278 ENSG00000132693 ENSG00000292003 ENSG00000182326 ENSG00000236625 PMC8394119__F1 NAD+ Precursors and Antioxidants for the Treatment of Amyotrophic Lateral Sclerosis ENSG00000111537 ENSG00000096717 ENSG00000142082 PMC6142327__F3 Role of AMPK signalling pathway during compensatory growth in pigs ENSG00000111057 PMC6109777__F4 Cellular protection mechanism conferred by Nrf2-ARE pathway after intracerebral hemorrhage (ICH) ENSG00000181019 ENSG00000178573 ENSG00000156273 ENSG00000079999 PMC12191222__F3 Top2b-regulated gene, Ubb, is a key player in protein degradation and transcriptional regulation in the retina ENSG00000150991 PMC2703816__F3 Identification of neuronal target genes for CCAAT/Enhancer Binding Proteins ENSG00000012048 ENSG00000099330 ENSG00000245848 ENSG00000187239 ENSG00000070831 ENSG00000146648 ENSG00000095002 PMC12191222__F2 Top2b-regulated gene, Bbs7, is an essential protein for BBSome-mediated ciliary trafficking ENSG00000127328 ENSG00000163818 PMC12191222__F5 Top2b-regulated gene, Cetn2, maintains photoreceptor ciliary structure and function ENSG00000153140 ENSG00000292191 ENSG00000166851 PMC5777730__F8 Phosphoproteome profiling reveals critical role of JAK-STAT signaling in maintaining chemoresistance in breast cancer ENSG00000104812 ENSG00000213928 ENSG00000005339 ENSG00000165119 ENSG00000198793 ENSG00000158517 ENSG00000131095 ENSG00000091138 ENSG00000173327 ENSG00000179295 ENSG00000115415 ENSG00000269404 ENSG00000022267 ENSG00000115145 PMC12191222__F4 Top2b-regulated gene, Rbp4, is crucial for retinoid transport and visual cycle ENSG00000138207 ENSG00000197713 PMC11855151__F10 Chemokine signaling pathway (KEGG: hsa04062) illustrates gene regulation differences between AF and EU prostate cancer patients, highlighting the influence of lncRNAs identified through structural equivalence analysis ENSG00000169291 ENSG00000002330 ENSG00000070831 ENSG00000088926 ENSG00000132639 ENSG00000143631 PMC4818686__F4 Rho Family GTPase signaling pathway alterations in adenoid cystic carcinoma ENSG00000163914 ENSG00000131095 ENSG00000288461 PMC5377334__F3 Systems approach to characterize the metabolism of liver cancer stem cells expressing CD133 ENSG00000136997 ENSG00000137203 ENSG00000185591 ENSG00000164949 PMC2874116__F2 Intrinsic pathway is deregulated in cancer ENSG00000002330 ENSG00000146648 PMC3652812__F4 Thymidylate Synthase Expression Determines Pemetrexed Targets and Resistance Development in Tumour Cells ENSG00000228716 ENSG00000198793 PMC4686057__F4 Transcriptome Analysis of Ullrich Congenital Muscular Dystrophy Fibroblasts Reveals a Disease Extracellular Matrix Signature and Key Molecular Regulators ENSG00000074590 ENSG00000064042 ENSG00000155961 ENSG00000030419 ENSG00000122966 ENSG00000171488 ENSG00000108960 ENSG00000134986 ENSG00000091490 ENSG00000139117 ENSG00000046604 ENSG00000144354 ENSG00000148848 ENSG00000178573 ENSG00000180263 ENSG00000091039 ENSG00000106772 ENSG00000069188 ENSG00000135424 ENSG00000111371 ENSG00000198948 ENSG00000136040 ENSG00000154175 PMC8452875__F7 Circadian Clock-Controlled Checkpoints in the Pathogenesis of Complex Disease ENSG00000096717 PMC9512240__F4 Radiation-induced Cell Death and Its Mechanisms ENSG00000168003 ENSG00000162711 ENSG00000151012 ENSG00000167468 PMC3165008__F1 An iron homeostasis regulatory circuit with reciprocal roles in Candida albicans commensalism and pathogenesis ENSG00000137078 ENSG00000288204 PMC4686057__F1 Transcriptome Analysis of Ullrich Congenital Muscular Dystrophy Fibroblasts Reveals a Disease Extracellular Matrix Signature and Key Molecular Regulators ENSG00000058085 ENSG00000169031 ENSG00000197565 ENSG00000081052 ENSG00000134871 ENSG00000164171 ENSG00000188153 ENSG00000169231 ENSG00000137801 ENSG00000204262 ENSG00000053747 ENSG00000213949 ENSG00000206384 ENSG00000186340 ENSG00000291748 ENSG00000026508 ENSG00000135424 ENSG00000108821 PMC9512240__F1 Radiation-induced Cell Death and Its Mechanisms ENSG00000070831 PMC8541427__F4 Genetics of Diabetes: What We Can Learn from Drosophila PMC8541427__F2 Genetics of Diabetes: What We Can Learn from Drosophila ENSG00000136111 PMC3277713__F1 A schematic diagram of different components making up the interleukin-23 (IL-23) and IL-12 receptors and the common signal transduction and activator of transcription 4 (STAT4) activation pathway ENSG00000162594 ENSG00000096996 ENSG00000138378 ENSG00000105397 PMC8452875__F1 Circadian Clock-Controlled Checkpoints in the Pathogenesis of Complex Disease ENSG00000165030 ENSG00000105516 ENSG00000146469 PMC3684430__F1 Apoptotic pathways regulated by the UPR ENSG00000128272 ENSG00000197930 ENSG00000144895 ENSG00000171791 ENSG00000127191 PMC5538425__F1 Calcineurin–NFAT signalling in myeloid leucocytes: new prospects and pitfalls in immunosuppressive therapy ENSG00000174125 ENSG00000239732 ENSG00000170458 ENSG00000136869 PMC11506434__F6 NPS-1034-targeted pathways in RCC ENSG00000167601 ENSG00000116717 PMC8763273__F4 Upregulation of T Cell Receptor Signaling Pathway Components in Gestational Diabetes Mellitus Patients: Joint Analysis of mRNA and circRNA Expression Profiles ENSG00000291603 ENSG00000100906 ENSG00000038002 PMC8667725__F4 Corona Virus Disease 2019 (COVID-19) as a System-Level Infectious Disease With Distinct Sex Disparities ENSG00000281244 ENSG00000110799 ENSG00000130234 ENSG00000136869 ENSG00000198670 ENSG00000122194 PMC8463986__F1 Brain insulin resistance: an early risk factor for Alzheimer's disease development in Down syndrome ENSG00000142192 ENSG00000169047 ENSG00000198793 ENSG00000096717 PMC7595734__F3 Lipid scavenging by extracellular arthropod-borne pathogens ENSG00000173599 ENSG00000026103 PMC8216348__F9 Computational-Based Drug Repurposing Method Targeting SARS-CoV-2 and its Neurological Manifestations Genes and Signaling Pathways ENSG00000007908 ENSG00000112715 ENSG00000073756 ENSG00000023839 PMC6855178__F1 Action of Targeted Therapies in Metastatic Renal Cell Carcinoma ENSG00000167601 ENSG00000019991 ENSG00000134086 ENSG00000198793 PMC11654217__F4 Mechanistic overview of targeting PD-1/PD-L1 by bioactive natural compounds ENSG00000115415 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC11654217__F1 Proposed signaling pathway representing PD-1, PD-L1, and their interactions ENSG00000154342 ENSG00000115415 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC8581865__F6 Dura cells in the etiopathogenesis of Crouzon syndrome: the effects of FGFR2 mutations in the dura cells on the proliferation of osteoblasts through the hippo/YAP mediated transcriptional regulation pathway ENSG00000150457 ENSG00000131023 PMC6360698__F2 Molecular signaling of inflammatory pathways involved in structural remodeling ENSG00000170365 ENSG00000137834 ENSG00000183735 ENSG00000170458 ENSG00000102871 ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000168040 ENSG00000175104 PMC3590793__F1 ATR barrier to replication-born DNA damage ENSG00000175054 ENSG00000164053 ENSG00000276618 PMC12191222__F7 Top2b-regulated gene, Crx, is a master regulator of photoreceptor development and maintenance ENSG00000105392 ENSG00000285493 PMC12191222__F6 Top2b-regulated gene, Pik3r1, represents a pivotal signaling cascade in photoreceptor cells ENSG00000124102 ENSG00000108389 PMC7456566__F3 Rhabdomyosarcoma ENSG00000160867 ENSG00000135446 ENSG00000150907 ENSG00000198793 ENSG00000129152 ENSG00000166851 ENSG00000140443 ENSG00000197461 PMC11654217__F5 Impact of natural compounds targeting PD-1/PD-L1 on various signaling pathways ENSG00000291971 ENSG00000167468 PMC11889221__F4 Metabolic differences between M1 and M2 macrophages PMC11889221__F6 Tissue Macrophages in Diseases ENSG00000149311 ENSG00000169245 ENSG00000142192 ENSG00000108691 ENSG00000118785 ENSG00000277943 PMC6554685__F9 Cell Cycle and TGF-beta-Signaling Pathway Regulated by the E2F Alteration in Breast CancerThe (A) cell cycle and (B) TGF-beta-signaling pathway regulated by the E2F alteration in breast cancer (cBioPortal) are shown ENSG00000118007 ENSG00000156574 ENSG00000134363 ENSG00000117399 ENSG00000137801 ENSG00000093009 ENSG00000145604 ENSG00000111537 ENSG00000095739 ENSG00000132646 ENSG00000113558 ENSG00000123374 ENSG00000164754 PMC10255599__F3 Anti-oxidant and anti-thrombotic activity of Vitamin D and Resveratrol in COVID-19 ENSG00000162711 ENSG00000117601 ENSG00000189403 PMC10255599__F2 Vitamin D and resveratrol immune response against SARS-CoV-2 infection ENSG00000111012 ENSG00000162711 ENSG00000096717 ENSG00000168610 PMC7719781__F5 Mitochondria-associated endoplasmic reticulum (ER) membrane (MAM) regulates ER stress and insulin signaling ENSG00000116688 PMC4036287__F9 Working model for Fas signaling in cancer-related inflammation and breast cancer progression ENSG00000168040 ENSG00000062485 ENSG00000026103 PMC6762062__F1 Inflammation-related bioactive lipid mediators in Toxocara canis- and Toxocara cati-induced neurotoxocarosis PMC2908618__F7 Elucidating the CXCL12/CXCR4 Signaling Network in Chronic Lymphocytic Leukemia through Phosphoproteomics Analysis ENSG00000162889 ENSG00000107562 ENSG00000005882 ENSG00000198793 ENSG00000121966 PMC3741506__F1 ASC-mediated switch between pyroptosis and apoptosis: intracellular pathogens and their products lead to activation of the ASC-dependent inflammasome ENSG00000132906 ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000064012 ENSG00000164305 PMC4833425__F6 Ghrelin Inhibits Post-Operative Adhesions via Blockage of the TGFB Signaling Pathway ENSG00000123496 ENSG00000105329 ENSG00000121853 ENSG00000175104 PMC6320700__F1 Novel Sphingolipid-Based Cancer Therapeutics in the Personalized Medicine Era ENSG00000139624 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000143418 PMC2891586__F3 Protein–Protein Interactions Essentials: Key Concepts to Building and Analyzing Interactome Networks ENSG00000004975 ENSG00000107404 ENSG00000109320 ENSG00000100060 ENSG00000178498 ENSG00000184916 ENSG00000135144 ENSG00000090932 ENSG00000110042 ENSG00000106003 ENSG00000091073 ENSG00000143801 ENSG00000163840 ENSG00000283780 ENSG00000128917 ENSG00000078747 ENSG00000205155 ENSG00000124232 ENSG00000273529 ENSG00000133961 ENSG00000161202 ENSG00000114315 PMC5445378__F1 EGF-R and TGFB signaling pathways interfered by E5 ENSG00000146648 PMC5445378__F3 Interferon synthesis and signaling pathways ENSG00000159128 ENSG00000105397 ENSG00000115415 ENSG00000027697 ENSG00000142166 PMC5445378__F2 E5 immune evasion mechanisms ENSG00000146648 PMC5908975__F7 FAK/paxillin/AKT signaling pathway ENSG00000087245 ENSG00000100985 PMC4565673__F1 How to Turn On an Ancient Metabolic Enzyme? Add Insulin and Deacetylate ENSG00000171720 ENSG00000198793 PMC11545938__F1 Sphingosine-1-Phosphate Signaling Pathway in Pancreatic Diseases ENSG00000063176 ENSG00000170989 ENSG00000213694 ENSG00000125910 ENSG00000267534 PMC9240646__F7 Whole picture of human stratum corneum ceramides, including the chain-length diversity of long-chain bases ENSG00000179148 ENSG00000179477 ENSG00000170426 ENSG00000143753 ENSG00000221968 ENSG00000168350 ENSG00000138385 PMC7153006__F12 Schematic diagram depicting the cytoprotective effects of Kaji-ichigoside F1 and Rosamultin on hypoxia-induced apoptosis of EA.hy926 endothelial cells ENSG00000002330 ENSG00000171791 PMC9338646__F1 Mechanism research and treatment progress of NAD pathway related molecules in tumor immune microenvironment ENSG00000187531 ENSG00000169291 ENSG00000105835 ENSG00000278488 ENSG00000124523 ENSG00000100985 ENSG00000077463 ENSG00000008130 ENSG00000096717 ENSG00000142082 ENSG00000089163 PMC4123363__F2 The p38A/ERK cross-talk in colorectal cancer ENSG00000096717 PMC7451565__F5 Genome-wide association study for mammary structure in Canadian Angus cows ENSG00000018236 ENSG00000099139 ENSG00000181195 ENSG00000127838 ENSG00000129744 ENSG00000132170 ENSG00000179921 PMC7451565__F4 Genome-wide association study for mammary structure in Canadian Angus cows ENSG00000101782 ENSG00000281459 ENSG00000280549 ENSG00000280908 ENSG00000154928 ENSG00000132693 PMC11117599__F5 SO2 exerts its antifibrotic effects by modulating key intracellular signaling cascades ENSG00000168036 PMC11117599__F4 Anti-fibrosis mechanisms of H2 in fibrotic diseases ENSG00000162711 ENSG00000198793 PMC11117599__F3 Anti-fibrosis mechanisms of H2S PMC11117599__F2 Anti-fibrosis mechanisms of CO ENSG00000162711 ENSG00000086991 PMC11117599__F1 Anti-fibrosis and fibrogenesis mechanisms of NO/NOS system PMC6631643__F9 Schematic representation of macrophage-derived exosomal miR-501-3p in PDAC and the involvement of TGFBR3-mediated TGFB signaling pathway ENSG00000153944 PMC7408826__F2 Deciphering the Molecular Landscape of Cutaneous Squamous Cell Carcinoma for Better Diagnosis and Treatment ENSG00000083857 ENSG00000128944 ENSG00000148400 ENSG00000135446 ENSG00000136997 ENSG00000081277 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC3650130__F216 Recently, Anderson and co-workers described cycloisomerization of O-allyl oximes into pyrroles catalyzed by the Ir(I)/Ag(I)-combined system PMC8223819__F1 Dynamics of host immune responses to SARS-CoV-2 ENSG00000134460 ENSG00000019991 ENSG00000007171 ENSG00000182326 ENSG00000164342 PMC11025274__F2 Mechanisms by which the gut microbiota promotes CRC metastasis by targeting seeds ENSG00000108691 ENSG00000167207 ENSG00000139287 ENSG00000170558 ENSG00000168036 ENSG00000136869 ENSG00000106100 ENSG00000146648 PMC9020229__F3 Endocrine Regulation on Bone by Thyroid ENSG00000168036 ENSG00000140443 PMC8036642__F3 MicroRNAs, Long Non-Coding RNAs, and Circular RNAs: Potential Biomarkers and Therapeutic Targets in Pheochromocytoma/Paraganglioma ENSG00000110693 PMC9020229__F1 Endocrine Regulation on Bone by Thyroid ENSG00000162552 ENSG00000170365 ENSG00000168036 ENSG00000163501 ENSG00000140443 PMC2581553__F7 The PpsB product and the proposed interaction between the PDIM and FAS-II pathways ENSG00000123999 ENSG00000026103 PMC4748276__F5 ApoCanD: Database of human apoptotic proteins in the context of cancer ENSG00000102871 ENSG00000138794 ENSG00000171791 ENSG00000168040 ENSG00000026103 PMC5757244__F5 Unifying Views of Autism Spectrum Disorders: A Consideration of Autoregulatory Feedback Loops ENSG00000198576 PMC5757244__F3 Unifying Views of Autism Spectrum Disorders: A Consideration of Autoregulatory Feedback Loops ENSG00000019991 ENSG00000138795 ENSG00000281324 ENSG00000128512 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000150394 ENSG00000188763 ENSG00000164778 PMC10532049__F1 Angiogenesis—An Emerging Role in Organ Fibrosis ENSG00000138316 ENSG00000137077 ENSG00000126353 ENSG00000203883 ENSG00000150630 PMC11810461__F1 MiRNAs that regulate 5-FU resistance in GI cancers ENSG00000188641 ENSG00000178951 ENSG00000079999 ENSG00000105894 ENSG00000162368 ENSG00000112242 ENSG00000089685 ENSG00000155011 ENSG00000173599 ENSG00000111653 ENSG00000145321 ENSG00000070950 ENSG00000120868 ENSG00000155760 ENSG00000139687 ENSG00000125968 ENSG00000158050 PMC7275405__F8 Graph of the interaction pathway ENSG00000171105 ENSG00000130164 ENSG00000138039 ENSG00000103569 ENSG00000103375 ENSG00000156096 ENSG00000143921 PMC3795998__F1 Signaling pathways of the UPR in response to ER-stress ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC3508164__F12 Proposed model of Cripto-1 modulation of the Wnt/Beta-catenin signaling pathway ENSG00000154342 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4661376__F3 Actin signaling pathways and their association with brain disorders ENSG00000106683 ENSG00000070831 ENSG00000170558 ENSG00000079482 ENSG00000168036 ENSG00000213523 PMC7680337__F3 Signaling networks involved in Ras-driven oncogenesis ENSG00000068028 ENSG00000156299 PMC3708280__F1 A simplified scheme of signaling pathways and cellular events involved in embryonic skeletal muscle formation ENSG00000154342 ENSG00000154764 ENSG00000164690 ENSG00000125084 PMC9338646__F3 Mechanism research and treatment progress of NAD pathway related molecules in tumor immune microenvironment ENSG00000169245 ENSG00000183735 ENSG00000164430 ENSG00000111537 ENSG00000105835 ENSG00000138336 ENSG00000115415 ENSG00000125347 PMC2832191__F3A Regulation of autophagy induction in yeast and mammalian cells ENSG00000144895 ENSG00000169047 ENSG00000198793 ENSG00000171791 PMC6222750__F6 Proposed signaling pathway triggered by kaempferol in EJ cells ENSG00000149311 ENSG00000002330 PMC3708280__F3 Molecular background of major signaling pathways responsible for proper development of muscles and muscle stem cells in normal tissues and tissues affected by laminopathy ENSG00000111049 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000136153 ENSG00000138777 ENSG00000114315 PMC2882188__F3 Complement cascade ENSG00000009724 ENSG00000113600 ENSG00000203710 ENSG00000244731 ENSG00000236625 PMC2821718__F3 Structure and signalling in the IL-17 receptor superfamily ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000163702 PMC3994321__F1 Autophagic pathways in mammalian cells ENSG00000152348 ENSG00000198382 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC4924722__F1 The essential role of methylthioadenosine phosphorylase in prostate cancer ENSG00000099810 ENSG00000123505 ENSG00000167900 PMC4890907__F3 Roles of Vitamin A Metabolism in the Development of Hepatic Insulin Resistance ENSG00000042832 ENSG00000124253 ENSG00000026103 PMC5514737__F6 Targeting cancer cell integrins using gold nanorods in photothermal therapy inhibits migration through affecting cytoskeletal proteins ENSG00000106683 ENSG00000291971 ENSG00000149269 ENSG00000182541 PMC2848030__F6 How the presence of virus acts on innate immune system components, i.e ENSG00000089127 ENSG00000138798 ENSG00000149294 PMC2964976__F8 CD36 participates in a signaling pathway that regulates ROS formation in murine VSMCs ENSG00000135218 ENSG00000010810 PMC9600888__F1 Iron Oxide Nanoparticles Combined with Static Magnetic Fields in Bone Remodeling ENSG00000170365 ENSG00000162337 ENSG00000168036 ENSG00000102575 ENSG00000083799 ENSG00000175104 ENSG00000131196 ENSG00000143387 PMC5714869__F6 Schema depicting the Peli1-mediated pathway following SAH ENSG00000172936 ENSG00000136869 PMC10216440__F2 CGRP cellular pathway ENSG00000132329 ENSG00000128272 ENSG00000291837 PMC7482807__F3 Regulatory function of lncRNAs in BC resistance to anti-HER2 targeted therapy ENSG00000223573 ENSG00000122566 ENSG00000172936 PMC9358258__F14 Neuroprotective Drug Discovery From Phytochemicals and Metabolites for CNS Viral Infection: A Systems Biology Approach With Clinical and Imaging Validation ENSG00000213658 ENSG00000115415 ENSG00000177606 ENSG00000143839 PMC7482807__F2 LncRNAs-mediated endocrine therapy resistance ENSG00000146648 ENSG00000140443 ENSG00000164086 PMC6850367__F2 PPARy‐mediated effects in the liver ENSG00000135218 ENSG00000042832 ENSG00000026103 PMC3061277__F1 Simple schema of the IGF pathway and approaches to its inhibition ENSG00000002330 ENSG00000198793 PMC4865316__F8 Scheme of the mechanisms by which the lack of ZO-2 triggered cell hypertrophy ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC2730990__F2 TGFB can leave you breathless ENSG00000134982 ENSG00000197971 PMC7449914__F7 Proposed mechanism: HDAC3 regulates the transcription of cGAS by deacetylating p65 at K122, which plays a role in ischemic/reperfusion-induced neuroinflammation and brain injury ENSG00000183735 ENSG00000164430 ENSG00000171720 PMC11749404__F1 Synthesis of Phospholipids in association of ER to mitochondria ENSG00000088766 ENSG00000173599 ENSG00000184207 ENSG00000133027 PMC5378054__F4 Regulation of cellular senescence by transforming growth factor B (TGFB) signaling ENSG00000185591 ENSG00000205250 PMC6416297__F1 Reaction-based specification of the model according to the notation previously introduced ENSG00000228716 ENSG00000136371 ENSG00000116984 PMC11620636__F7 LncRNAs induced by SARS-CoV-2 can exert cis-regulation on the IL-27 pathway ENSG00000125740 ENSG00000117228 ENSG00000163874 ENSG00000162654 ENSG00000276561 ENSG00000154451 ENSG00000169245 ENSG00000111537 ENSG00000134321 ENSG00000077150 ENSG00000115415 ENSG00000163235 ENSG00000177606 ENSG00000135114 ENSG00000134070 ENSG00000184371 ENSG00000164400 ENSG00000105246 ENSG00000111331 ENSG00000113302 ENSG00000184216 PMC8624248__F2 Molecular Mechanisms and Cellular Contribution from Lung Fibrosis to Lung Cancer Development ENSG00000107562 ENSG00000137673 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000164690 PMC4898271__F6 The ras signaling pathway ENSG00000138798 ENSG00000135333 ENSG00000146648 PMC8171374__F1 Immune Thrombocytopenia: Recent Advances in Pathogenesis and Treatments ENSG00000203710 ENSG00000103522 PMC2834863__F1 Transforming growth factor beta (TGFB) and inflammation in cancer ENSG00000023734 ENSG00000157933 ENSG00000070831 ENSG00000198742 ENSG00000163914 ENSG00000095015 ENSG00000175104 ENSG00000122194 PMC5378054__F1 Transforming growth factor B (TGFB) signaling pathway and its context-dependent regulation ENSG00000113600 ENSG00000198742 PMC6209915__F8 Ras pathway was hyperactivated in Sorafenib-resistant SKOV-3 cells ENSG00000291603 ENSG00000213658 ENSG00000070831 ENSG00000010810 ENSG00000135446 ENSG00000006451 ENSG00000186716 ENSG00000177606 ENSG00000280477 ENSG00000155903 ENSG00000099942 PMC7482807__F4 LncRNAs-regulated resistance to targeted therapies beyond HER2 ENSG00000171720 ENSG00000081913 ENSG00000065526 ENSG00000105401 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC8364356__F1 Imbalanced Coagulation in the Airway of Type-2 High Asthma with Comorbid Obesity ENSG00000160752 ENSG00000122194 PMC5770599__F3 Regulation of important signaling pathways by E3 ubiquitin ligases in CRC ENSG00000145604 ENSG00000157764 ENSG00000134982 ENSG00000198793 ENSG00000123374 ENSG00000146648 PMC5770599__F2 Regulation of Wnt/Beta-catenin signaling and oncogenic NFKB pathway by ubiquitylating enzymes in CRC ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000177606 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000175104 PMC3407218__F5 CXCL12/CXCR4 Axis Triggers the Activation of EGF Receptor and ERK Signaling Pathway in CsA-Induced Proliferation of Human Trophoblast Cells ENSG00000087245 ENSG00000107562 ENSG00000291971 ENSG00000138798 ENSG00000146648 ENSG00000121966 PMC5180413__F10 a In tumor cells expressing ERB (MDA-MB-231, MCF-7), Gamma- and D-T3 bind to and activate the ERB receptor, inducing the expression of pro-apoptotic genes such as MIC-1, EGR-1, and cathepsin-D, finally triggering apoptosis ENSG00000100219 PMC9656396__F3 Metabolic Pathways, Enzymes, and Metabolites: Opportunities in Cancer Therapy ENSG00000131473 ENSG00000118515 ENSG00000169710 ENSG00000008130 ENSG00000135250 ENSG00000109670 PMC7299160__F11 Anti-Ferroptosis Drug Enhances Total-Body Irradiation Mitigation by Drugs that Block Apoptosis and Necroptosis ENSG00000151012 ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000164305 ENSG00000168003 ENSG00000167468 ENSG00000111684 ENSG00000145321 ENSG00000168404 ENSG00000064012 ENSG00000285379 PMC11087971__F4 The ECM-receptor interaction pathway and (B) the IL-17 signaling pathway ENSG00000148346 ENSG00000135218 ENSG00000042832 ENSG00000168743 ENSG00000110799 ENSG00000163220 ENSG00000168040 ENSG00000127191 ENSG00000143556 ENSG00000163702 ENSG00000076604 ENSG00000136457 ENSG00000149968 ENSG00000026508 ENSG00000152592 ENSG00000157625 ENSG00000100985 ENSG00000175104 PMC7957536__F1 Leptin signalling ENSG00000169047 ENSG00000198793 ENSG00000168610 PMC9146657__F5 Integrated Transcriptomics and Nontargeted Metabolomics Analysis Reveal Key Metabolic Pathways in Ganoderma lucidum in Response to Ethylene ENSG00000160752 ENSG00000073578 ENSG00000105953 PMC4613493__F1 Keap1/Nrf2 pathway in the frontiers of cancer and non-cancer cell metabolism ENSG00000065833 PMC5830027__F2 Metabolic pathway of NUCKS1 in physiological and pathological process ENSG00000069275 PMC4613493__F2 Keap1/Nrf2 pathway in the frontiers of cancer and non-cancer cell metabolism ENSG00000065833 ENSG00000169710 PMC8128161__F2 ER protein quality control capacity in metazoans is monitored by the three branches of the unfolded protein response ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8234989__F1 New Insights into the Clinical Implications of Yes-Associated Protein in Lung Cancer: Roles in Drug Resistance, Tumor Immunity, Autophagy, and Organoid Development ENSG00000167601 ENSG00000163914 ENSG00000136997 ENSG00000131023 ENSG00000102974 PMC7938660__F1 Metabolic formation of hydroxynorketamines from ketamine ENSG00000197408 ENSG00000255974 PMC5295849__F9 Proposed model of CXCL12 signaling to mTORC1 in BMM ENSG00000124102 ENSG00000107562 ENSG00000124181 ENSG00000121966 PMC5449256__F1 Oncogenic growth factor signaling mediating tumor escape from cellular immunity ENSG00000108691 ENSG00000115415 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC6219204__F2 Crosstalk of FGF10 during pancreatic cancer ENSG00000070193 ENSG00000125398 ENSG00000148926 ENSG00000140285 ENSG00000146648 ENSG00000131196 PMC3175613__F3 Proposed in vivo innate and adaptive immune responses to AAV vectors ENSG00000239732 ENSG00000203710 PMC5240660__F1 Phylogenetic and conserved synteny analysis of PTH related proteins ENSG00000142538 ENSG00000152266 ENSG00000164530 ENSG00000010030 ENSG00000137409 ENSG00000087842 ENSG00000162777 ENSG00000255587 ENSG00000133059 ENSG00000112079 PMC3980610__F1 LIF/JAK/STAT3-mediated growth inhibitory signaling in medullary thyroid cancer ENSG00000128342 ENSG00000168610 PMC3106121__F1 Phosphodiesterases and Cardiac cGMP: Evolving Roles and Controversies ENSG00000285109 ENSG00000117152 ENSG00000116741 ENSG00000137672 PMC3964949__F3 Motif-mediated interactions annotated in the ELM resource mapped onto the KEGG () human Phosphatidylinositol-3′-kinase-(PI3K)–Akt signaling pathway (hsa04151) ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000136869 PMC4140952__F1 CPAcP interaction with HER-2 and PI3K/Akt pathway in regulating prostate cell homeostasis ENSG00000002330 PMC5809759__F1 Can Controlling Endoplasmic Reticulum Dysfunction Treat Allergic Inflammation in Severe Asthma With Fungal Sensitization? ENSG00000128272 ENSG00000100219 PMC4016833__F1 Signaling events in murine heart development and cardiac ESC differentiation ENSG00000156574 ENSG00000138606 ENSG00000089225 ENSG00000016082 PMC3347317__F2 Modulation of type I IFN production by PRRSV ENSG00000183735 ENSG00000187608 ENSG00000105397 ENSG00000178732 ENSG00000131323 ENSG00000135828 ENSG00000276561 ENSG00000164342 PMC7102917__F2 Major downstream signaling pathways in GISTs ENSG00000157404 ENSG00000198793 ENSG00000134853 ENSG00000168610 PMC5682898__F7 Proposed model for the neuroprotective effects of XJDH in OGD/R injury ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC5240660__F9 Evolutionary history of the PTH family in vertebrates ENSG00000142538 ENSG00000118972 ENSG00000187097 ENSG00000173868 ENSG00000062485 PMC3314445__F9 An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated AB oligomers ENSG00000169047 ENSG00000281879 PMC9525705__F1 mtDNA acts as a DAMP to activate neuroinflammation ENSG00000162711 ENSG00000239732 ENSG00000125538 PMC9280480__F2 SUMOylation Targets Associated With Wnt/Beta-Catenin Pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000153201 ENSG00000026508 ENSG00000196628 PMC6073455__F4 SCF and its active ingredients protect against inflammation in NDs ENSG00000102871 ENSG00000172936 ENSG00000136869 ENSG00000168040 ENSG00000175104 ENSG00000127191 PMC2955993__F3 Complement and Periodontitis ENSG00000174125 PMC2955993__F1 Complement and Periodontitis ENSG00000203710 ENSG00000117335 ENSG00000166278 ENSG00000182326 PMC5543471__F8 Molecular mechanism of the mTOR pathway in Vil‐Cre;Pkd2 f3/f3 mice, with or without rapamycin treatment ENSG00000105656 ENSG00000123374 PMC9553089__F2 Dysregulation of the mevalonate pathway during SARS-CoV-2 infection: An in silico study ENSG00000006695 ENSG00000160752 ENSG00000164219 ENSG00000152904 ENSG00000147955 ENSG00000163914 ENSG00000197429 ENSG00000110651 ENSG00000189403 ENSG00000167508 ENSG00000168522 PMC4478622__F1 Scheme of the engineered metabolic pathway for the production of 1,2-propanediol and 1-propanol in C ENSG00000205221 ENSG00000141034 PMC5989173__F1 Molecular mechanism of SOCS- and IRF-regulated cytokine signaling in macrophages during ALI/ARDS PMC8380478__F2 Effectivity of mesenchymal stem cells for bleomycin-induced pulmonary fibrosis: a systematic review and implication for clinical application ENSG00000178860 ENSG00000137077 ENSG00000026103 PMC9497173__F1 Targeting the Metabolic Rewiring in Pancreatic Cancer and Its Tumor Microenvironment ENSG00000125166 ENSG00000065833 ENSG00000197713 ENSG00000198380 ENSG00000122966 ENSG00000172005 ENSG00000153574 ENSG00000166123 ENSG00000115419 ENSG00000159399 PMC7290664__F6 Functions of caspase-2 in DNA damage and cellular stress ENSG00000149311 ENSG00000175054 ENSG00000171791 ENSG00000254550 PMC2640319__F1 Insulin and amino acid signaling pathway leading to the stimulation of translation initiation ENSG00000169047 ENSG00000198793 PMC7290664__F9 Extrinsic and intrinsic pathways of apoptosis ENSG00000102871 ENSG00000171791 ENSG00000168040 ENSG00000026103 PMC9497173__F3 Targeting the Metabolic Rewiring in Pancreatic Cancer and Its Tumor Microenvironment ENSG00000177169 ENSG00000123395 ENSG00000083290 ENSG00000126775 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC8198409__F2 Diacylglycerol Kinase alpha in X Linked Lymphoproliferative Disease Type 1 ENSG00000065357 ENSG00000010810 PMC10942825__F6 Signaling pathways of DUSP22 in EndMT PMC5869001__F6 Hypothesized KS biosynthetic pathway in the absence of functional B3GnT7 ENSG00000121578 ENSG00000135702 ENSG00000183196 PMC4376865__F4 H-Ferritin-Regulated MicroRNAs Modulate Gene Expression in K562 Cells ENSG00000241258 ENSG00000155827 ENSG00000143970 PMC1560089__F7 Proposed LITAF signaling pathway ENSG00000172936 ENSG00000136869 ENSG00000189067 PMC9329130__F1 Over-expression of a cyanobacterial gene for 1-deoxy-d-xylulose-5-phosphate synthase in the chloroplast of Chlamydomonas reinhardtii perturbs chlorophyll: carotenoid ratios ENSG00000197429 ENSG00000062485 PMC11395697__F8 Tumor–immune interactions and the dynamic interplay between tumor killing and immunosuppressive mechanisms ENSG00000019991 ENSG00000099985 ENSG00000134982 ENSG00000138798 ENSG00000180644 ENSG00000112715 ENSG00000108691 ENSG00000108688 ENSG00000118520 ENSG00000006606 ENSG00000100985 ENSG00000106178 ENSG00000062485 PMC5541935__F2 Comparison of Biomarker Expression between Proximal and Distal Colorectal Adenomas: The Tennessee-Indiana Adenoma Recurrence Study ENSG00000164379 ENSG00000281324 ENSG00000291971 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC11395697__F7 Gut microbiome–host interactions in colorectal cancer development ENSG00000172936 ENSG00000136869 PMC4928883__F3 Fundamentals of cancer metabolism ENSG00000284320 ENSG00000131473 ENSG00000065911 ENSG00000100714 ENSG00000092621 ENSG00000173599 ENSG00000163738 ENSG00000115419 ENSG00000159399 PMC11395697__F4 The colitis-associated cancer pathway in inflammatory bowel disease ENSG00000134982 ENSG00000168610 PMC11395697__F3 Serrated neoplasia routes ENSG00000157764 ENSG00000170430 PMC4629535__F5 Canonical pathway and gene network analysis of the 18 identifiers that were expressed in the lungs of PQ-free rats ENSG00000134020 ENSG00000143147 ENSG00000149930 ENSG00000160299 ENSG00000117174 ENSG00000095015 ENSG00000183840 ENSG00000155903 ENSG00000067369 ENSG00000166068 ENSG00000285069 ENSG00000187840 ENSG00000108061 ENSG00000108963 ENSG00000197372 ENSG00000173264 ENSG00000073803 ENSG00000133606 ENSG00000291480 ENSG00000104228 ENSG00000164054 ENSG00000173890 ENSG00000138271 PMC4629535__F4 Proposed p53 signaling pathway in PQ-treated rat lungs ENSG00000104499 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000110711 ENSG00000064393 ENSG00000168036 ENSG00000112378 ENSG00000078237 ENSG00000026103 PMC7701955__F2 Canonical and non‐canonical TGF‐B signaling ENSG00000100290 ENSG00000125398 ENSG00000070831 ENSG00000198742 ENSG00000198793 ENSG00000086991 ENSG00000049768 ENSG00000175104 ENSG00000076604 ENSG00000026103 PMC3724248__F1 MicroRNA pathway is universal to all mammalian miRNAs ENSG00000128191 ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC3944819__F7 Schematic of ANDV N and GnGc protein regulation of TBK1 signaling ENSG00000183735 ENSG00000088888 ENSG00000131323 PMC4629535__F6 Canonical pathway and gene network analysis of the 26 identifiers that were expressed in the lungs of PQ-treated rats ENSG00000152782 ENSG00000156709 ENSG00000080819 ENSG00000095015 ENSG00000179364 ENSG00000172315 ENSG00000080546 ENSG00000160469 ENSG00000150991 ENSG00000154133 ENSG00000160703 ENSG00000196352 ENSG00000185591 ENSG00000197763 ENSG00000134258 ENSG00000146385 ENSG00000064393 ENSG00000172543 ENSG00000164543 ENSG00000132478 ENSG00000102967 ENSG00000101695 ENSG00000127334 ENSG00000160691 ENSG00000111145 ENSG00000115977 ENSG00000168564 ENSG00000183337 ENSG00000196131 ENSG00000143507 ENSG00000147138 ENSG00000168264 ENSG00000171759 PMC6225148__F2 Current understanding of the mechanism of action of T-oligos ENSG00000149311 PMC2275788__F2 Mapping Genetically Compensatory Pathways from Synthetic Lethal Interactions in Yeast ENSG00000149823 ENSG00000134371 ENSG00000120805 ENSG00000138175 ENSG00000276463 ENSG00000111237 ENSG00000070950 ENSG00000051180 ENSG00000164105 PMC10819295__F2 Possible signaling pathways activated by ORF8 ENSG00000172936 ENSG00000175104 ENSG00000177663 PMC11847756__F3 Topological analysis of the PPI network using Cytoscape identified 10 key hub genes, shown in this network visualization ENSG00000177606 ENSG00000171791 ENSG00000168610 ENSG00000164305 ENSG00000163631 PMC8469696__F2 Valosin-Containing Protein (VCP)/p97: A Prognostic Biomarker and Therapeutic Target in Cancer ENSG00000167671 ENSG00000165280 ENSG00000091542 ENSG00000163960 ENSG00000075089 ENSG00000175073 ENSG00000198168 ENSG00000172554 ENSG00000170100 ENSG00000158062 ENSG00000168936 ENSG00000215114 ENSG00000132530 ENSG00000162543 ENSG00000180667 ENSG00000100483 ENSG00000117614 ENSG00000169696 ENSG00000164902 ENSG00000137055 PMC7537271__F3 SARS‐CoV‐2 activates innate immune pathways ENSG00000162711 ENSG00000183735 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC3077544__F2 Akt regulates numerous biological functions by phosphorylating distinct protein substrates ENSG00000145604 ENSG00000002330 ENSG00000149269 ENSG00000198793 ENSG00000288169 PMC3994404__F2 KIT signaling pathways ENSG00000157404 ENSG00000115415 ENSG00000124181 ENSG00000168610 ENSG00000010671 PMC11847756__F2 PPI network was constructed using STRING to visualize the interactions among the 140 shared targets between Chrysin and breast cancer ENSG00000280962 ENSG00000044115 ENSG00000103222 ENSG00000168036 ENSG00000087586 ENSG00000255974 ENSG00000049768 ENSG00000106546 ENSG00000078900 ENSG00000129214 ENSG00000077782 ENSG00000128513 ENSG00000087245 ENSG00000108786 ENSG00000137673 ENSG00000100906 ENSG00000173039 ENSG00000160182 ENSG00000081051 ENSG00000168610 ENSG00000007171 ENSG00000169245 ENSG00000274247 ENSG00000196502 ENSG00000177606 ENSG00000132646 ENSG00000023839 PMC4466411__F5 Schematic model of the molecular mechanisms associated with PD-induced autophagy in NCI-H460 and A549 cells ENSG00000198793 ENSG00000144848 PMC8235734__F4 Impact of the Tumor Microenvironment on Macrophage Polarization in Cancer Metastatic Progression ENSG00000108691 ENSG00000107562 ENSG00000184371 ENSG00000121807 ENSG00000121966 PMC4511109__F3 Live to die another way: modes of programmed cell death and the signals emanating from dying cells ENSG00000137275 ENSG00000102871 ENSG00000131323 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000064012 ENSG00000164305 ENSG00000285379 PMC11505501__F1 Mechanisms underlying signaling pathway crosstalk in OA ENSG00000170365 ENSG00000170909 ENSG00000259207 ENSG00000004948 ENSG00000168036 ENSG00000102575 ENSG00000175104 ENSG00000121966 ENSG00000143387 PMC7682347__F7 NFKB/leukemia inhibitory factor/STAT3 signaling pathway in antibody-mediated suppression of Sindbis virus replication in neurons ENSG00000128342 ENSG00000168610 PMC8430581__F2 Large Granular Lymphocytic Leukemia: From Immunopathogenesis to Treatment of Refractory Disease ENSG00000162594 ENSG00000134982 ENSG00000198793 ENSG00000168610 PMC12046027__F8 Interferon-Induced OAS-RNase L/PKR Pathway and the effect of hnRNP A1 depletion ENSG00000134321 ENSG00000089127 ENSG00000185745 ENSG00000135828 ENSG00000276561 ENSG00000164342 PMC4780366__F4 Molecular hypothesis of tumor progression in uveal melanoma, highlighting the role of PRAME reported herein ENSG00000163930 ENSG00000115524 ENSG00000173674 PMC3574814__F1 MYC target genes in the polyamine pathway ENSG00000136997 ENSG00000163577 ENSG00000123505 ENSG00000116649 PMC7311357__F1 Illustration of the main components of the ACE/ANGII/AT1R and ACE2/ANG(1–7)/MASR axes along with the other molecular components reported to be involved in SARS-CoV-2 infection (e.g ENSG00000140564 ENSG00000134982 ENSG00000130234 ENSG00000184012 PMC10623085__F7 Proposed signaling pathway by which NE mediates HepG2 cell proliferation PMC5452197__F3 Schematic representation of the intestinal inflammatory pathway expression altered by Hydryeast supplementation (DHY8) in dextran sodium sulfate (DSS)-induced colitis ENSG00000138378 ENSG00000111537 ENSG00000167207 ENSG00000187837 PMC5642390__F6 The diagram of a potential signaling pathway that RACK1 regulates the cell proliferation and cell invasion in cervical cancer cells ENSG00000115415 PMC4445275__F1 Genes involved in the leukocyte transendothelial migration and Toll-like receptor signaling pathways ENSG00000170458 ENSG00000168040 ENSG00000135605 ENSG00000143387 PMC3551337__F3 CRM1 regulates the PI3K signaling pathway in MCL ENSG00000186716 ENSG00000123374 ENSG00000010671 PMC7064362__F5 Inhibitory Effect of Rosae Multiflorae Fructus Extracts on the Receptor Activator of NFKB Ligand-Induced Osteoclastogenesis through Modulation of P38- and Ca2+-Mediated Nuclear Factor of Activated T-Cells Cytoplasmic 1 Expression ENSG00000095585 ENSG00000175104 ENSG00000131196 ENSG00000135605 ENSG00000010671 PMC8909792__F3 Ehrlichia chaffeensis intracellular life cycle and host innate response ENSG00000239732 ENSG00000167207 ENSG00000172936 PMC10520786__F2 Nrf2-mediated therapeutic effects of dietary flavones in different diseases ENSG00000010810 ENSG00000096717 ENSG00000079999 PMC8909792__F2 Rickettsia spp. intracellular life cycle and host innate responses ENSG00000162711 ENSG00000042832 ENSG00000172936 ENSG00000136869 PMC7136166__F1 Clinical practice recommendations for growth hormone treatment in children with chronic kidney disease ENSG00000152266 PMC12031180__F7 CTN induces apoptosis and cell cycle arrest via the TGFB signaling pathway, and 4-HDK mitigates these effects ENSG00000164305 ENSG00000124762 PMC10520786__F3 Nrf2 modulates inflammation and apoptosis ENSG00000079999 PMC8038462__F2 DNA repair pathway in the prostate epithelium involving hereditary prostate cancer (HPCa) related genes: mismatch repair or MMR (A); homologous recombination or HR (B) ENSG00000012048 ENSG00000083093 ENSG00000105486 ENSG00000095002 ENSG00000122512 ENSG00000139618 ENSG00000183765 PMC10992410__F2 Metabolic engineering strategies for de novo biosynthesis of sterols and steroids in yeast ENSG00000157554 ENSG00000116691 ENSG00000197487 PMC10755469__F2 Crosstalk between neutrophil extracellular traps and immune regulation: insights into pathobiology and therapeutic implications of transfusion-related acute lung injury ENSG00000278718 ENSG00000162711 ENSG00000164430 ENSG00000005381 PMC7871890__F1 Type I and III interferons response following SARS-CoV-2 sensing during controlled (left and central cell) and uncontrolled (right cell) infection ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000130234 ENSG00000185436 ENSG00000125538 ENSG00000172936 ENSG00000125347 ENSG00000142166 PMC7871890__F2 IFN signaling through the Jak-STAT pathway ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000147896 PMC9146752__F1 Research Progress on Transorgan Regulation of the Cardiovascular and Motor System through Cardiogenic Exosomes ENSG00000274336 ENSG00000074319 ENSG00000184216 ENSG00000178568 PMC8902450__F8 Gallic Acid Hindered Lung Cancer Progression by Inducing Cell Cycle Arrest and Apoptosis in A549 Lung Cancer Cells via PI3K/Akt Pathway PMC3184062__F9 Scheme for poly(I:C)-induced apoptotic signaling pathway in high TLR3-expressing NB cells (left panel), but not low TLR3-expressing NB cells (right panel) ENSG00000164342 PMC7251113__F1 Proposed mechanism of synergy of co-encapsulated vitamin E succinate modified octahistidine-octaarginine (VES-H8R8) and palmityl-doxorubicin (pDOX) ENSG00000113905 ENSG00000047936 ENSG00000184207 PMC2836529__F3 Neurotrophin actions on the endothelial cell ENSG00000087245 ENSG00000112715 PMC3157706__F1 Molecular pathways in LSCs of CML ENSG00000198793 ENSG00000168036 ENSG00000275565 PMC11948946__F8 Analysis of gene expression related to hormone signaling pathways ENSG00000105722 ENSG00000110934 ENSG00000221818 PMC6997396__F5 Autophagy in metabolic syndrome: breaking the wheel by targeting the renin–angiotensin system ENSG00000042832 ENSG00000198793 PMC8574122__F1 PI3K/Akt/mTOR pathway: A potential pharmacological target in COVID-19 ENSG00000118515 ENSG00000155792 ENSG00000167965 PMC11850271__F2 Regulatory role of posttranslational modifications in the activation of RIPK1 ENSG00000183735 ENSG00000123240 ENSG00000137275 ENSG00000102871 ENSG00000157625 ENSG00000083799 ENSG00000168040 ENSG00000285379 PMC11850271__F1 TNF-Alpha-driven formation of necroptosis-specific protein complexes ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC3275810__F2 Schematic display of the molecular interactions of apoptosis related molecules in dental apoptosis indicating the central position of the mitochondria pathway, which has been shown to be essential ENSG00000135960 ENSG00000168040 PMC11118972__F5 Effect of pteF deletion on cell metabolism ENSG00000122966 ENSG00000172005 ENSG00000198670 PMC1215521__F7 Possible gene regulation in macrophage THP-1 stimulated by theophylline ENSG00000135218 ENSG00000185339 ENSG00000150630 PMC4338781__F4 DMXAA modulates mTOR signaling pathway in A549 cells.Notes: A549 cells were treated with DMXAA 10 μM for 24 hours and the protein samples were subject to quantitative proteomic analysis ENSG00000177169 ENSG00000163435 ENSG00000171105 ENSG00000169047 ENSG00000173599 ENSG00000164327 PMC3606085__F4 NER pathway ENSG00000113456 ENSG00000132646 PMC4338781__F3 Proteomic response to 5,6-dimethylxanthenone 4-acetic acid (DMXAA, vadimezan) in human non-small cell lung cancer A549 cells determined by the stable-isotope labeling by amino acids in cell culture (SILAC) approach ENSG00000102034 ENSG00000198793 ENSG00000163914 PMC4137134__F1 Conceivable transforming growth factor (TGF)B1-initiated cellular events leading to myofibroblast activation and extracellular matrix (ECM) synthesis culminating into renal fibrosis ENSG00000137834 ENSG00000004142 ENSG00000163914 ENSG00000086991 PMC6914774__F1 The emerging treatment landscape of targeted therapy in non-small-cell lung cancer ENSG00000157764 ENSG00000138798 ENSG00000198793 PMC7755476__F9 Protein-protein interaction network of E2F coexpression genes (GeneMANIA) ENSG00000114346 ENSG00000100162 ENSG00000111665 ENSG00000112242 ENSG00000163235 ENSG00000102890 ENSG00000132383 ENSG00000197299 ENSG00000188529 ENSG00000282941 ENSG00000283060 ENSG00000168701 ENSG00000138180 ENSG00000108106 PMC6050903__F1 Regulated cell death signaling pathways ENSG00000143799 ENSG00000137275 ENSG00000167468 ENSG00000125538 ENSG00000285379 PMC3086918__F1 Mind the dbGAP: The Application of Data Mining to Identify Biological Mechanisms ENSG00000000457 ENSG00000105329 ENSG00000000971 ENSG00000000005 PMC8495593__F2 Xeroderma Pigmentosum C: A Valuable Tool to Decipher the Signaling Pathways in Skin Cancers PMC8495593__F1 Xeroderma Pigmentosum C: A Valuable Tool to Decipher the Signaling Pathways in Skin Cancers ENSG00000281324 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC8495593__F3 Xeroderma Pigmentosum C: A Valuable Tool to Decipher the Signaling Pathways in Skin Cancers ENSG00000132646 ENSG00000136936 PMC4547588__F1 Interferons and other inflammatory cytokines control HBV infection of hepatocytes via multiple, distinct mechanisms ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000125538 PMC8236123__F9 Activated neutrophils polarize protumorigenic interleukin‐17A‐producing T helper subsets through TNF‐A‐B7‐H2‐dependent pathway in human gastric cancer ENSG00000163464 ENSG00000169429 ENSG00000124875 PMC3115056__F1 Regulation of neural process growth, elaboration and structural plasticity by NFKB ENSG00000242689 ENSG00000102871 ENSG00000291971 PMC8578378__F1 IL-17 signaling pathway in mucosal candidiasis ENSG00000143546 ENSG00000105397 ENSG00000112115 ENSG00000163702 PMC12008290__F10 Astragalus mongholicus and Hedyotis diffusa willd inhibit cell proliferation by attenuating the miR-582-3p-p27 signaling pathway in LUAD ENSG00000135446 ENSG00000123374 PMC5984065__F5 TGFB induces Smad2 Phosphorylation, ARE Induction, and Trophoblast Differentiation Diagrammatic representation of the TGFB signaling pathway in SM10 growth inhibition and trophoblast differentiation PMC3356111__F9 Schematic representation of TNF’s dual effect on rat pinealocytes ENSG00000100906 ENSG00000173039 PMC2954716__F4 Developmental Programming: Differential Effects of Prenatal Testosterone Excess on Insulin Target Tissues ENSG00000169047 ENSG00000198793 ENSG00000164327 ENSG00000105723 PMC8096095__F5 SRI-21979 alters the expression of transcripts involved in cAMP signaling and apoptosis ENSG00000160789 ENSG00000104899 ENSG00000002330 ENSG00000143933 ENSG00000171791 ENSG00000168040 ENSG00000127191 ENSG00000107175 ENSG00000164305 ENSG00000087460 ENSG00000149311 ENSG00000104237 ENSG00000125398 ENSG00000149269 ENSG00000163914 ENSG00000135116 ENSG00000160293 ENSG00000026103 PMC2743116__F1 Ras/mitogen-activated protein kinase (MAPK) signaling pathway and associated developmental syndromes (indicated by dashed lines) ENSG00000157764 ENSG00000115904 ENSG00000166068 ENSG00000196712 PMC9604790__F3 Integrating Genetic Alterations and the Hippo Pathway in Head and Neck Squamous Cell Carcinoma for Future Precision Medicine ENSG00000083857 ENSG00000141867 ENSG00000186575 ENSG00000026508 ENSG00000135404 ENSG00000277273 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC10748259__F8 Antiviral effectors and cell metabolism interactions ENSG00000187608 ENSG00000138135 ENSG00000105397 ENSG00000089127 ENSG00000185436 ENSG00000135828 ENSG00000142166 PMC10748259__F7 Involvement of metabolism in viral genome detection ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000082512 ENSG00000131323 ENSG00000127191 ENSG00000276561 ENSG00000164342 PMC10748259__F6 Molecular mechanisms leading to the detection of viral genome ENSG00000162711 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000082512 ENSG00000131323 ENSG00000127191 ENSG00000276561 ENSG00000164342 ENSG00000076604 PMC8471503__F8 Identifying GPSM Family Members as Potential Biomarkers in Breast Cancer: A Comprehensive Bioinformatics Analysis ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000105664 ENSG00000134982 ENSG00000117399 PMC4142049__F3 LOX-1 signaling mechanistically links atherosclerosis, hypertension, and diabetes ENSG00000198793 ENSG00000166278 ENSG00000096717 PMC3569116__F1 Glucose metabolic pathway ENSG00000091140 PMC7698460__F3 Recent strategies aimed at targeting TAMs in combination with ICIs for melanoma treatment ENSG00000177575 ENSG00000118520 ENSG00000112715 PMC12184675__F3 CGAS-STING signaling pathway in immune responses to SARS-CoV-2 and DNA ENSG00000164430 ENSG00000276561 PMC12184675__F2 Molecular mechanisms of SARS-CoV-2-induced pulmonary injury via apoptotic pathways ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC2279300__F6 Chlamydial Entry Involves TARP Binding of Guanine Nucleotide Exchange Factors ENSG00000115904 ENSG00000160293 PMC10380759__F2 Clinical Significance of CD73 in Cancer PMC5992506__F2 Cholesterol synthesis and cancer cell proliferation ENSG00000105656 ENSG00000146648 PMC12184675__F4 Depiction of the innate immune signalling pathway, focusing on RIG-I/MDA-5/MAVS and their inhibition by SARS-CoV-2 proteins ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000154174 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC6052888__F8 Diverse Roles of Mitochondria in Immune Responses: Novel Insights Into Immuno-Metabolism ENSG00000198793 ENSG00000136997 ENSG00000047936 ENSG00000079999 PMC6657305__F1 Cellular Compartmentation and the Redox/Nonredox Functions of NAD+ ENSG00000105835 ENSG00000291814 ENSG00000162882 PMC8321875__F4 Neuroprotective Potential of Ellagic Acid: A Critical Review ENSG00000169047 ENSG00000079999 PMC7590081__F1 Catabolic pathways regulating TG levels in cells ENSG00000042832 ENSG00000100344 ENSG00000026103 PMC6052888__F9 Antioxidants neutralize mitochondrial ROS (mtROS) ENSG00000175567 ENSG00000142082 ENSG00000100294 PMC5632899__F1 Schematic diagram of an IL-33 signaling pathway ENSG00000137033 ENSG00000172936 ENSG00000175104 PMC6657305__F3 Cellular Compartmentation and the Redox/Nonredox Functions of NAD+ ENSG00000166321 ENSG00000008130 PMC6052888__F5 Tryptophan metabolism mediated immune cell response ENSG00000134982 ENSG00000198793 ENSG00000142082 ENSG00000106546 PMC4072077__F1 MicroRNAs (miRNAs) are involved in pathogenesis of multiple myeloma (MM) by targeting some signaling pathways in myeloma cells ENSG00000288210 ENSG00000101843 ENSG00000168610 ENSG00000184216 ENSG00000140443 PMC7258858__F1 Actions of thyroid hormones (THs) and their corresponding receptors ENSG00000180210 ENSG00000103811 ENSG00000140564 ENSG00000090402 ENSG00000150907 ENSG00000104371 ENSG00000137193 ENSG00000168036 ENSG00000123374 PMC4069681__F1 Rho protein GTPases and their interactions with NFKB: crossroads of inflammation and matrix biology ENSG00000111537 ENSG00000070831 ENSG00000143878 ENSG00000169750 ENSG00000102871 ENSG00000186716 ENSG00000125538 ENSG00000095015 ENSG00000067900 ENSG00000127191 PMC8465440__F2 Scoparone inhibits pancreatic cancer through PI3K/Akt signaling pathway ENSG00000178999 ENSG00000163629 ENSG00000291971 ENSG00000095015 ENSG00000087586 ENSG00000108443 ENSG00000196396 ENSG00000010671 ENSG00000158125 ENSG00000292210 ENSG00000128052 ENSG00000037280 ENSG00000143603 ENSG00000275565 ENSG00000140443 ENSG00000167434 ENSG00000162889 ENSG00000074590 ENSG00000104365 ENSG00000171105 ENSG00000157764 ENSG00000081237 ENSG00000007908 ENSG00000006062 ENSG00000124588 ENSG00000143387 ENSG00000105397 ENSG00000163131 ENSG00000164024 ENSG00000100784 ENSG00000005381 ENSG00000074410 ENSG00000138398 ENSG00000146648 ENSG00000127948 ENSG00000198355 ENSG00000262243 PMC4263464__F1 Top overlapped pathways for non-users (top) and users (bottom) of oral contraceptives.Notes: Hexagon shaped are genes ENSG00000175866 ENSG00000075975 ENSG00000241553 ENSG00000169047 ENSG00000138071 ENSG00000101266 ENSG00000171791 ENSG00000099942 ENSG00000155974 ENSG00000076928 ENSG00000172216 ENSG00000136997 ENSG00000123374 ENSG00000105810 ENSG00000125968 ENSG00000027075 ENSG00000104365 ENSG00000005339 ENSG00000196090 ENSG00000065361 ENSG00000175793 ENSG00000109320 ENSG00000077157 ENSG00000147381 ENSG00000250506 ENSG00000065559 ENSG00000067900 ENSG00000135446 ENSG00000177606 ENSG00000130733 ENSG00000132964 ENSG00000121060 ENSG00000146648 ENSG00000141456 PMC7865483__F7 Key players of the CoA biosynthetic pathway in bacteria, yeast and mammals ENSG00000138621 ENSG00000068120 ENSG00000127125 PMC3630363__F8 Temporal restriction of the Cdk1/Cdc5/Mus81 pathway outside S phase is important for genome integrity ENSG00000070950 PMC11721695__S1 hCeO2@CA-074Me Nanoparticles Alleviate Inflammation and Improve Osteogenic Microenvironment by Regulating the CTSB-NLRP3 Signaling Pathway ENSG00000162711 PMC9598519__F10 Glutathione and Glutaredoxin in Redox Regulation and Cell Signaling of the Lens ENSG00000291971 ENSG00000146648 PMC3925422__F3 Breaking bad: Manipulation of the host response by Porphyromonas gingivalis ENSG00000174125 ENSG00000111537 ENSG00000170458 ENSG00000136869 ENSG00000125347 PMC5985449__F2 Sialic acid metabolic pathway ENSG00000159921 ENSG00000170191 ENSG00000111726 ENSG00000095380 PMC7487050__F2 Metastatic process in breast cancer ENSG00000169554 ENSG00000107562 ENSG00000122691 ENSG00000170558 ENSG00000101115 ENSG00000175592 ENSG00000112715 ENSG00000105996 ENSG00000166135 PMC7487050__F1 Brief summary of miRNA biogenesis and aspects of regulation in breast cancer and metastasis ENSG00000136158 ENSG00000100697 ENSG00000146648 ENSG00000128191 ENSG00000113360 ENSG00000165819 ENSG00000123908 PMC4750533__F1 The Akt pathway and downstream effectors ENSG00000177455 ENSG00000033327 ENSG00000090402 ENSG00000002330 ENSG00000069482 ENSG00000186716 ENSG00000169047 ENSG00000155792 ENSG00000276876 PMC7487050__F3 TGFB stimulation of EMT, angiogenesis, and stemness in breast cancer progression toward metastasis ENSG00000169554 ENSG00000128710 ENSG00000128917 ENSG00000148400 ENSG00000122691 ENSG00000074181 ENSG00000101115 ENSG00000112715 ENSG00000184916 ENSG00000137845 ENSG00000090932 PMC8224563__F1 Autophagy Induction as a Host-Directed Therapeutic Strategy against Mycobacterium tuberculosis Infection ENSG00000177169 ENSG00000123395 ENSG00000198382 ENSG00000123240 ENSG00000083290 ENSG00000126775 ENSG00000089041 ENSG00000096717 ENSG00000142082 PMC5985295__F2 IFN-dependent and -independent ISG transcription mediated by complexes comprised unphosphorylated STATs ENSG00000159128 ENSG00000105397 ENSG00000027697 ENSG00000142166 PMC7744330__F8 Genetic pathways disrupted by ENPP1 deficiency provide insight into mechanisms of osteoporosis, osteomalacia, and paradoxical mineralization ENSG00000118972 ENSG00000156076 ENSG00000154122 ENSG00000197594 ENSG00000104332 ENSG00000177283 PMC5985295__F5 Cooperation of unphosphorylated and phosphorylated ISGF3 and GAF components and IRF1 in the regulation of basal and IFN-induced transcription ENSG00000159128 ENSG00000213928 ENSG00000004455 ENSG00000027697 ENSG00000125347 ENSG00000142166 PMC7047626__F2 Mitophagy and DNA Damage Signaling in Human Aging ENSG00000135655 ENSG00000110497 ENSG00000166233 ENSG00000048707 ENSG00000198742 ENSG00000005893 ENSG00000158828 ENSG00000069509 ENSG00000247077 ENSG00000135093 PMC8853826__F1 Insulin synthesis and secretion in the islet Beta-cell and its control by mirNas ENSG00000196218 PMC7047626__F4 Mitophagy and DNA Damage Signaling in Human Aging ENSG00000143799 ENSG00000149311 ENSG00000183735 ENSG00000164430 ENSG00000198793 ENSG00000165392 ENSG00000158828 ENSG00000096717 PMC4808853__F2 Long chain polyunsaturated fatty acid biosynthetic pathway ENSG00000134824 ENSG00000149485 ENSG00000197977 PMC10520679__F1 Exosomal non-coding RNAs: Blueprint in colorectal cancer metastasis and therapeutic targets ENSG00000129219 ENSG00000041353 ENSG00000291971 ENSG00000168461 ENSG00000165527 ENSG00000146648 ENSG00000111737 PMC8853826__F2 Insulin signal transduction and metabolic responses in peripheral tissues and their control by mirNas ENSG00000120833 ENSG00000150907 PMC7744330__F3 Genetic pathways disrupted by ENPP1 deficiency provide insight into mechanisms of osteoporosis, osteomalacia, and paradoxical mineralization ENSG00000138316 ENSG00000185070 ENSG00000162337 ENSG00000160161 ENSG00000169884 ENSG00000169231 ENSG00000105894 ENSG00000186340 ENSG00000166523 ENSG00000157227 ENSG00000197594 ENSG00000152785 ENSG00000152592 ENSG00000183682 ENSG00000118972 ENSG00000152266 ENSG00000087245 ENSG00000164694 ENSG00000002745 ENSG00000133110 ENSG00000118785 ENSG00000111799 ENSG00000188517 ENSG00000291748 ENSG00000084636 PMC10520679__F3 An illustration demonstrates the involvement of ncRNAs and oncogenic signaling pathways in CRC metastasis ENSG00000182718 ENSG00000196371 ENSG00000198793 PMC11575262__F9 Seed and foliar application of nano-selenium improves sesame triacylglycerols and oil yield via photosynthetic pigment and enzymatic and chemical antioxidant enhancement revealed by spectrophotometric, UHPLC-analysis and chemometric modeling ENSG00000173599 ENSG00000154258 ENSG00000167701 PMC8230057__F1 How SARS-CoV-2 and Other Viruses Build an Invasion Route to Hijack the Host Nucleocytoplasmic Trafficking System ENSG00000111605 ENSG00000124789 ENSG00000101146 ENSG00000132661 ENSG00000126883 ENSG00000110713 ENSG00000166278 ENSG00000213024 ENSG00000132341 PMC9204157__F6 Targeting Growth Factor and Cytokine Pathways to Treat Idiopathic Pulmonary Fibrosis ENSG00000183735 ENSG00000069482 ENSG00000198793 ENSG00000163914 ENSG00000135341 ENSG00000140443 PMC5748001__F3 Flexible Roles for Proteoglycan Sulfation and Receptor Signaling ENSG00000291971 ENSG00000198793 ENSG00000163914 ENSG00000169783 ENSG00000146648 PMC10418475__F1 Melanocortin 1 Receptor (MC1R): Pharmacological and Therapeutic Aspects ENSG00000080166 PMC2831232__F2 NKT cells in immune-mediated pregnancy loss ENSG00000158473 ENSG00000239732 ENSG00000134982 ENSG00000136869 PMC3595309__F5 Cadherin-17 induces tumorigenesis and lymphatic metastasis in gastric cancer through activation of NFKB signaling pathway ENSG00000079112 ENSG00000150630 PMC3118659__F13 NAD+ biosynthesis and salvage pathways ENSG00000105835 ENSG00000278488 PMC4688896__F1 Dysregulation and restoration of translational homeostasis in fragile X syndrome ENSG00000005882 ENSG00000198793 PMC2963142__F1 TLR signaling pathway and downstream effector molecules ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC6523349__F3 YAP regulation in early stages of prostate cancer ENSG00000157554 ENSG00000186575 ENSG00000139926 ENSG00000131023 PMC8506026__F7 Crosstalk Between Abnormal TSHR Signaling Activation and PTEN/PI3K in the Dedifferentiation of Thyroid Cancer Cells ENSG00000198793 ENSG00000165409 PMC3417478__F1 Cyclic AMP elevation leads to induction of the SOCS-3 gene in VECs ENSG00000168610 PMC11635874__F2 BMP signaling pathway in bone regeneration ENSG00000170365 ENSG00000137834 ENSG00000198742 PMC11635874__F1 TGFB signaling in bone PMC2827416__F5 Impact of high dietary protein on lipid metabolism in porcine adipose tissue at body weight 60 kg ENSG00000042832 ENSG00000026103 PMC3707951__F3 Proposed intracellular effects of S100A1, S100A4, and S100A8/S100A9 ENSG00000143546 ENSG00000136999 ENSG00000163220 ENSG00000145321 ENSG00000196218 ENSG00000196154 ENSG00000168036 ENSG00000198626 PMC10472646__F3 Targeting ubiquitin specific proteases (USPs) in cancer immunotherapy: from basic research to preclinical application ENSG00000107562 ENSG00000096717 ENSG00000101557 PMC4267164__F2 NOD1 and NOD2 signaling ENSG00000104856 ENSG00000112977 ENSG00000167207 ENSG00000157625 ENSG00000106100 PMC4267164__F1 TLRs signaling ENSG00000174125 ENSG00000183735 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 PMC10472646__F1 Targeting ubiquitin specific proteases (USPs) in cancer immunotherapy: from basic research to preclinical application ENSG00000163599 ENSG00000049768 PMC3707951__F4 S100A8 induction in macrophages ENSG00000143546 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000168610 ENSG00000164342 PMC4506691__F2 Pathways of steroid hormone synthesis in 21-hydroxylase deficiency, including backdoor pathway and 11-oxygenated androgens ENSG00000151632 ENSG00000203859 PMC6523349__F5 YAP/TAZ regulate prostate cancer stem cells (PCSCs) ENSG00000138735 ENSG00000150457 ENSG00000131023 PMC6523349__F4 Hippo pathway regulation of advanced prostate cancer ENSG00000244405 ENSG00000175832 ENSG00000150457 PMC11541314__F6 Codeine and morphine Metabolism pathway as the most significant curated signaling pathway with a p-value of 3 ENSG00000138115 ENSG00000171234 ENSG00000156096 ENSG00000023839 PMC2827416__F6 Impact of high dietary protein on lipid metabolism in porcine adipose tissue at body weight 100 kg ENSG00000042832 ENSG00000026103 PMC6301029__F4 Egg activation in Drosophila ENSG00000134982 PMC3792024__F4 Meta-Analysis Identifies NFKB as a Therapeutic Target in Renal Cancer ENSG00000173821 ENSG00000110721 ENSG00000105835 ENSG00000167207 ENSG00000187608 ENSG00000089127 ENSG00000171791 ENSG00000162772 ENSG00000095585 ENSG00000041982 ENSG00000038427 ENSG00000134326 ENSG00000136997 ENSG00000164761 ENSG00000196954 ENSG00000205220 ENSG00000125347 ENSG00000162654 ENSG00000276561 ENSG00000134900 ENSG00000106829 ENSG00000169245 ENSG00000123609 ENSG00000026508 ENSG00000162692 ENSG00000101670 ENSG00000169248 ENSG00000232326 ENSG00000104332 ENSG00000135899 ENSG00000132530 ENSG00000150782 ENSG00000140379 ENSG00000168310 ENSG00000177519 ENSG00000104432 ENSG00000164342 ENSG00000026103 ENSG00000118946 ENSG00000121552 ENSG00000104365 ENSG00000081041 ENSG00000231925 ENSG00000081189 ENSG00000110719 ENSG00000108691 ENSG00000117091 ENSG00000115415 ENSG00000164136 ENSG00000150630 PMC4726088__F9 Olanzapine Prevents the PCP-induced Reduction in the Neurite Outgrowth of Prefrontal Cortical Neurons via NRG1 ENSG00000178568 PMC7982428__F1 Hedgehog (HH) signaling pathway and its related regulators, target genes and current therapeutic landscape ENSG00000138795 ENSG00000156076 ENSG00000157764 ENSG00000138798 ENSG00000168036 ENSG00000171791 ENSG00000118777 ENSG00000168283 ENSG00000180447 ENSG00000112210 ENSG00000106571 ENSG00000078747 ENSG00000144857 ENSG00000166813 ENSG00000026508 ENSG00000128602 ENSG00000179399 PMC4562315__F1 Emerging roles of YAP and TAZ in cancer ENSG00000186575 ENSG00000109321 ENSG00000089685 ENSG00000114978 ENSG00000150457 ENSG00000114019 ENSG00000131023 PMC9442031__F2 Influence of the gut microbiota on endometriosis: Potential role of chenodeoxycholic acid and its derivatives ENSG00000276559 ENSG00000167910 ENSG00000180432 ENSG00000115271 ENSG00000135929 PMC3335841__F3 Reduced Expression of Inflammatory Genes in Deceased Donor Kidneys Undergoing Pulsatile Pump Preservation ENSG00000007944 ENSG00000003056 ENSG00000142192 ENSG00000214078 ENSG00000120693 ENSG00000105697 ENSG00000077514 ENSG00000025039 ENSG00000114573 ENSG00000135916 ENSG00000137642 ENSG00000141480 ENSG00000122223 ENSG00000182240 ENSG00000160223 ENSG00000103365 ENSG00000106628 PMC3335841__F2 Reduced Expression of Inflammatory Genes in Deceased Donor Kidneys Undergoing Pulsatile Pump Preservation ENSG00000094804 PMC7428719__F1 Ozone: a natural bioactive molecule with antioxidant property as potential new strategy in aging and in neurodegenerative disorders ENSG00000181019 ENSG00000198793 PMC8968680__F2 Anticancer Activity of Erianin: Cancer-Specific Target Prediction Based on Network Pharmacology ENSG00000132906 ENSG00000002330 ENSG00000134982 ENSG00000198793 PMC6591730__F3 Causes and Consequences of Enzyme-Induced Cytosine Deamination ENSG00000175054 ENSG00000130997 ENSG00000095002 PMC5716453__F6 Molecular mechanisms underlying the neuroprotective effect of IGFBP-6 via IGF-1R-dependent signaling ENSG00000167779 ENSG00000140443 PMC8968680__F3 Anticancer Activity of Erianin: Cancer-Specific Target Prediction Based on Network Pharmacology ENSG00000122025 ENSG00000135446 PMC6232560__F3 Oncogenic signaling network activated by bile acids ENSG00000168610 ENSG00000146648 PMC4141507__F1 fHLH: becoming a blended family ENSG00000135604 ENSG00000180644 ENSG00000132842 ENSG00000143669 PMC2483757__F1 Kinetic model of the EpoR/GATA-1 network implicated in erythrocyte progenitor commitment ENSG00000187266 PMC5669448__F3 Autoimmunity and autoinflammation: A systems view on signaling pathway dysregulation profiles ENSG00000110921 PMC5669448__F4 Autoimmunity and autoinflammation: A systems view on signaling pathway dysregulation profiles ENSG00000110921 ENSG00000140368 PMC9450364__F4 Effect of downregulated citrate synthase on oxidative phosphorylation signaling pathway in HEI-OC1 cells ENSG00000094880 ENSG00000105854 ENSG00000167118 ENSG00000128951 ENSG00000131495 ENSG00000156467 ENSG00000145293 ENSG00000167900 ENSG00000131143 ENSG00000109814 ENSG00000139180 ENSG00000136521 ENSG00000213619 ENSG00000186010 ENSG00000119013 ENSG00000083799 PMC6331455__F5 Role of Nrf2 in HCC ENSG00000160867 ENSG00000079999 PMC3418709__F1 Hepatitis C, Porphyria Cutanea Tarda, and Liver Iron: An Update ENSG00000010704 ENSG00000066926 ENSG00000126088 ENSG00000140505 PMC3551337__F2 Major pathogenic lesions in MCL ENSG00000104856 ENSG00000149311 ENSG00000186716 ENSG00000123374 ENSG00000131323 ENSG00000127191 PMC8618802__F7 Over Fifty Years of Life, Death, and Cannibalism: A Historical Recollection of Apoptosis and Autophagy ENSG00000149311 ENSG00000175054 ENSG00000198793 ENSG00000120868 ENSG00000168040 ENSG00000136048 PMC3874812__F8 Cav-1 phosphorylation-dependent LPS signaling pathway in mediating lung inflammation in endothelial cells ENSG00000170458 ENSG00000291971 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC3578301__F4 Early signaling events that underlie fate decisions of naive CD4+ T cells towards distinct T-helper cell subsets ENSG00000111537 ENSG00000107485 ENSG00000049768 ENSG00000184916 ENSG00000069667 PMC3578301__F3 Early signaling events that underlie fate decisions of naive CD4+ T cells towards distinct T-helper cell subsets ENSG00000107485 ENSG00000166278 PMC5600322__F2 HSC Niche Biology and HSC Expansion Ex Vivo ENSG00000143995 PMC4705475__F6 RYR2, PTDSS1 and AREG genes are implicated in a Lebanese population-based study of copy number variation in autism ENSG00000105835 ENSG00000149930 ENSG00000109321 ENSG00000197471 ENSG00000152977 ENSG00000116996 ENSG00000174943 ENSG00000198626 ENSG00000149922 ENSG00000179915 ENSG00000156471 PMC2805916__F1 Galectins, integrins and cell migration ENSG00000143537 ENSG00000185591 PMC7059861__F1 Main pathways of TRP degradation, including relevant enzymes [modified after (, )] ENSG00000188676 ENSG00000106546 PMC4562315__F3 Emerging roles of YAP and TAZ in cancer ENSG00000149311 ENSG00000078900 ENSG00000134982 ENSG00000168036 ENSG00000150457 ENSG00000168646 ENSG00000131023 PMC11174998__F1 One-carbon metabolism ENSG00000228716 ENSG00000002330 ENSG00000124275 PMC4562315__F2 Emerging roles of YAP and TAZ in cancer ENSG00000038382 ENSG00000126016 ENSG00000134982 ENSG00000144560 ENSG00000163914 ENSG00000100697 ENSG00000150457 ENSG00000131023 PMC7133116__F2 Current knowledge and recent advances in understanding metabolism of the model cyanobacterium Synechocystis sp. PCC 6803 ENSG00000261701 ENSG00000130957 ENSG00000197713 ENSG00000073578 ENSG00000153574 ENSG00000184207 PMC7897244__F1 TGFB signaling pathway ENSG00000121989 ENSG00000135409 ENSG00000204217 ENSG00000114739 PMC9204157__F2 Targeting Growth Factor and Cytokine Pathways to Treat Idiopathic Pulmonary Fibrosis ENSG00000136535 ENSG00000198793 ENSG00000122194 PMC7897244__F6 Proposed pathological roles of ligand competition ENSG00000170365 ENSG00000171759 PMC9204157__F4 Targeting Growth Factor and Cytokine Pathways to Treat Idiopathic Pulmonary Fibrosis ENSG00000176601 ENSG00000107562 ENSG00000291971 ENSG00000146648 ENSG00000121966 PMC10671169__F7 NXC736 Attenuates Radiation-Induced Lung Fibrosis via Regulating NLRP3/IL-1B Signaling Pathway ENSG00000162711 ENSG00000170989 ENSG00000125910 PMC11949690__F6 Findings—hypothalamic IGF1 signaling can be dynamically regulated ENSG00000171105 ENSG00000069482 ENSG00000164326 ENSG00000150907 ENSG00000169047 ENSG00000115138 ENSG00000134548 ENSG00000115461 ENSG00000140443 PMC5779870__F1 The PDGF signaling pathway ENSG00000172216 ENSG00000115415 PMC3827721__F4 In silico method for modelling metabolism and gene product expression at genome scale ENSG00000078053 ENSG00000111816 ENSG00000167701 PMC5255577__F7 Proposed model for the role of GAS6 in maintaining oral mucosal homeostasis ENSG00000140279 ENSG00000172936 ENSG00000049768 PMC9283897__F3 Bioinformatics Analysis Reveals FOXM1/BUB1B Signaling Pathway as a Key Target of Neosetophomone B in Human Leukemic Cells: A Gene Network-Based Microarray Analysis ENSG00000120889 ENSG00000170606 ENSG00000145386 ENSG00000139218 ENSG00000179295 ENSG00000183765 ENSG00000168538 ENSG00000012048 ENSG00000137807 ENSG00000138778 ENSG00000112242 ENSG00000014123 ENSG00000106346 ENSG00000136068 ENSG00000136492 ENSG00000023516 ENSG00000151657 ENSG00000065361 ENSG00000164109 ENSG00000103540 ENSG00000131747 ENSG00000123191 ENSG00000130638 ENSG00000138594 ENSG00000143228 ENSG00000138160 ENSG00000117724 ENSG00000198901 ENSG00000153208 ENSG00000117650 ENSG00000069869 ENSG00000148019 ENSG00000121481 ENSG00000112984 ENSG00000167325 ENSG00000132646 ENSG00000138303 ENSG00000115539 ENSG00000112697 ENSG00000117620 ENSG00000137822 ENSG00000029993 ENSG00000128487 ENSG00000114331 ENSG00000096717 ENSG00000144357 ENSG00000136021 ENSG00000067177 PMC6448793__F3 Ciliary signaling systems within tumors ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000171791 ENSG00000182621 ENSG00000106571 ENSG00000100592 ENSG00000136997 ENSG00000112655 ENSG00000134853 ENSG00000114315 ENSG00000128602 ENSG00000168646 PMC6224120__F2 Breast cancer signaling pathway ENSG00000143799 ENSG00000132906 ENSG00000124102 ENSG00000019991 ENSG00000110330 ENSG00000002330 ENSG00000138798 ENSG00000198793 ENSG00000169047 ENSG00000167658 ENSG00000141564 ENSG00000121879 ENSG00000067369 ENSG00000168610 ENSG00000164305 ENSG00000082175 ENSG00000128052 ENSG00000107485 ENSG00000146648 PMC5143371__F2 Cellular metabolic pathway involved in redox homeostasis ENSG00000065833 ENSG00000065911 ENSG00000100714 PMC5817809__F1 TKI-induced regulation of glycolytic pathway ENSG00000130957 ENSG00000074800 ENSG00000160883 ENSG00000108515 ENSG00000067057 ENSG00000136997 ENSG00000078237 ENSG00000164708 ENSG00000136872 ENSG00000159399 ENSG00000152556 PMC9313337__F4 Comparing Bayesian-Based Reconstruction Strategies in Topology-Based Pathway Enrichment Analysis ENSG00000120833 ENSG00000138378 ENSG00000105397 ENSG00000171150 ENSG00000114737 ENSG00000105639 ENSG00000180008 ENSG00000168610 PMC9313337__F3 Comparing Bayesian-Based Reconstruction Strategies in Topology-Based Pathway Enrichment Analysis ENSG00000105397 ENSG00000105639 PMC8745604__F1 YAP/TAZ Signaling Pathway in the Tumor Microenvironment and Carcinogenesis: Current Knowledge and Therapeutic Promises ENSG00000186575 ENSG00000065833 PMC8225793__F5 Mouse model of prenatal exposure to Interleukin-6 to study the developmental origin of health and disease ENSG00000142192 ENSG00000213928 ENSG00000108055 ENSG00000172005 ENSG00000197429 ENSG00000123374 ENSG00000073111 PMC9670319__F4 RNA-seq and qRT-PCR analyses reveal the physiological response to acute hypoxia and reoxygenation in Epinephelus coioides ENSG00000180210 ENSG00000242265 ENSG00000159224 ENSG00000288269 ENSG00000115263 ENSG00000198793 ENSG00000170145 ENSG00000100504 ENSG00000087460 ENSG00000127948 PMC8384902__F5 ASCL1, NKX2-1, and PROX1 co-regulate subtype-specific genes in small-cell lung cancer ENSG00000173404 ENSG00000159388 ENSG00000123454 ENSG00000117707 ENSG00000145386 ENSG00000196628 ENSG00000072571 ENSG00000138778 ENSG00000113456 ENSG00000168214 ENSG00000128917 ENSG00000078699 ENSG00000069188 ENSG00000121621 ENSG00000176597 ENSG00000067900 ENSG00000136352 ENSG00000184916 ENSG00000186298 ENSG00000090932 ENSG00000117399 ENSG00000106003 ENSG00000139352 ENSG00000105771 ENSG00000163435 ENSG00000065978 ENSG00000132872 ENSG00000100749 ENSG00000134057 ENSG00000198176 ENSG00000064692 ENSG00000076356 ENSG00000148154 ENSG00000114315 ENSG00000139800 PMC5979469__F3 Positive regulation of TERT by WNT signaling pathway specific protein (Beta-catenin) and STAT3; (B) SMAD transcriptionally repressed TERT; (C) BC032469, a lncRNA contained sequences which showed complementarity to miRNA-1207-5p seed regions ENSG00000164362 ENSG00000168036 ENSG00000168610 PMC8569443__F1 Functional Roles of Non-coding RNAs in the Interaction Between Host and Influenza A Virus ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000276561 PMC8745604__F4 YAP/TAZ Signaling Pathway in the Tumor Microenvironment and Carcinogenesis: Current Knowledge and Therapeutic Promises ENSG00000108342 ENSG00000184371 ENSG00000164400 ENSG00000146648 PMC8745604__F3 YAP/TAZ Signaling Pathway in the Tumor Microenvironment and Carcinogenesis: Current Knowledge and Therapeutic Promises ENSG00000147162 ENSG00000163914 ENSG00000174804 ENSG00000150457 ENSG00000165757 ENSG00000131023 PMC3917325__F1 Chondroitin sulfate and HS biosynthesis ENSG00000116199 ENSG00000176022 ENSG00000180767 ENSG00000131873 ENSG00000136213 ENSG00000171310 ENSG00000109956 ENSG00000111962 ENSG00000147408 ENSG00000147119 ENSG00000169105 ENSG00000123989 ENSG00000122863 ENSG00000285395 ENSG00000198108 ENSG00000112309 PMC5432387__F1 Type II Transmembrane Serine Protease Mediated Signaling in Cancer ENSG00000019991 ENSG00000291971 ENSG00000137648 ENSG00000198793 ENSG00000184012 PMC3660694__F1 Oncostatin M signaling pathway- NetSlim (http://www.netpath.org/netslim/NetSlim_114) map generated to graphically represent the different reactions induced by OSM in various cell types ENSG00000100234 ENSG00000291971 ENSG00000130522 ENSG00000050748 ENSG00000169047 ENSG00000198793 ENSG00000115904 ENSG00000164327 ENSG00000112715 ENSG00000164305 ENSG00000089159 ENSG00000130164 ENSG00000172216 ENSG00000145623 ENSG00000149968 ENSG00000166501 ENSG00000132906 ENSG00000027075 ENSG00000099985 ENSG00000100906 ENSG00000109320 ENSG00000173039 ENSG00000105639 ENSG00000168610 ENSG00000160691 ENSG00000120899 ENSG00000115415 PMC7238289__F1 Pathophysiology of Alcoholic Hepatitis and Mechanisms of Action of Novel Therapeutic Agents ENSG00000163739 ENSG00000169429 ENSG00000163631 PMC9615310__F1 Human ultrarare genetic disorders of sulfur metabolism demonstrate redundancies in H2S homeostasis ENSG00000137767 ENSG00000164690 ENSG00000116984 PMC5085669__F1 MTOR signaling network in mammalian cells ENSG00000177169 ENSG00000169047 ENSG00000155792 PMC8977320__F1 Edifying the Focal Factors Influencing Mesenchymal Stem Cells by the Microenvironment of Intervertebral Disc Degeneration in Low Back Pain ENSG00000178860 ENSG00000167580 ENSG00000106571 ENSG00000108684 ENSG00000214513 ENSG00000072182 ENSG00000007171 PMC10316197__F3 Apoptosis in NAFLD patient ENSG00000103202 ENSG00000135828 ENSG00000124193 PMC10316197__F2 Inflammation on NAFLD progression ENSG00000239732 ENSG00000118503 ENSG00000169047 ENSG00000136869 ENSG00000168610 PMC6067120__F4 Schematic representation of estrogen metabolism and AHR signaling pathways ENSG00000140505 ENSG00000140465 ENSG00000106546 PMC3740690__F1 Protein Tyrosine Phosphatases and Type 1 Diabetes: Genetic and Functional Implications of PTPN2 and PTPN22 ENSG00000004455 ENSG00000049768 PMC5522276__F2 HABP2 p.G534E variant in patients with family history of thyroid and breast cancer ENSG00000101670 ENSG00000057935 ENSG00000197948 ENSG00000179674 ENSG00000101230 ENSG00000100867 ENSG00000146872 ENSG00000137601 ENSG00000080345 ENSG00000030304 ENSG00000170606 ENSG00000165816 ENSG00000148396 ENSG00000179862 ENSG00000171502 ENSG00000067704 ENSG00000125414 ENSG00000112742 ENSG00000062485 ENSG00000136068 ENSG00000100079 ENSG00000070778 ENSG00000091656 ENSG00000135636 ENSG00000083290 ENSG00000137501 ENSG00000183072 ENSG00000088305 ENSG00000076706 ENSG00000181027 ENSG00000071564 ENSG00000136603 ENSG00000178814 ENSG00000196576 ENSG00000144283 ENSG00000120805 ENSG00000135409 ENSG00000134398 ENSG00000004897 ENSG00000135372 ENSG00000122779 ENSG00000124253 ENSG00000095002 ENSG00000100365 ENSG00000023839 PMC8345931__F8 Cytokine-Laden Extracellular Vesicles Predict Patient Prognosis after Cerebrovascular Accident ENSG00000189377 ENSG00000110711 ENSG00000275718 ENSG00000049130 ENSG00000108688 ENSG00000181374 ENSG00000163736 ENSG00000105698 ENSG00000106178 PMC8459566__F1 Hypofibrinolysis in type 2 diabetes and its clinical implications: from mechanisms to pharmacological modulation ENSG00000110799 ENSG00000169047 ENSG00000005381 ENSG00000122194 ENSG00000132693 PMC3504424__F5 Transforming growth factorB (TGFB) pathway PMC3504424__F4 Tyrosine kinase receptors pathway ENSG00000163914 ENSG00000177606 ENSG00000136997 ENSG00000146648 PMC3502106__F5 Feed-forward signaling in which FGF-9 controls Wnt-2a expression and mesenchymal Wnt/Beta-catenin signaling ENSG00000070193 ENSG00000188064 ENSG00000168036 PMC6214025__F9 Combined nano-therapy strategy of MSN containing DOX and AgNPs in cancerous cell ENSG00000104884 ENSG00000131747 ENSG00000214285 ENSG00000095002 ENSG00000158125 PMC11505109__F2 DNA damage response (DDR) pathway activates the ATM-CHK2-P53 signaling pathway and inhibits CDK2 expression, thereby affecting the G1/S transition ENSG00000149311 ENSG00000175054 ENSG00000123374 PMC3504424__F3 Canonical Wnt-Beta-catenin pathway ENSG00000134982 ENSG00000168036 PMC8745058__F4 High-Grade Cervical Intraepithelial Neoplasia (CIN) Associates with Increased Proliferation and Attenuated Immune Signaling ENSG00000169245 ENSG00000163739 ENSG00000131747 ENSG00000177606 ENSG00000136997 ENSG00000149294 ENSG00000100526 ENSG00000118520 ENSG00000100985 ENSG00000073756 ENSG00000115009 PMC6687873__F7 IRE1Alpha-XBP1 pathway of the UPR in CF ENSG00000136869 PMC7171093__F7 Activation of STAT3 is a key event in TLR4 signaling-mediated melanoma progression ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC6221911__F1 Phytochemical and Pharmacological Role of Liquiritigenin and Isoliquiritigenin From Radix Glycyrrhizae in Human Health and Disease Models ENSG00000143799 ENSG00000118518 ENSG00000198793 ENSG00000087085 ENSG00000171791 PMC9030253__F4 Phytoplankton Toxins and Their Potential Therapeutic Applications: A Journey toward the Quest for Potent Pharmaceuticals ENSG00000149311 ENSG00000168040 ENSG00000026103 PMC5458216__F7 Mechanism of modulation through PI3K-AKT pathway about Nepeta cataria L.’s extract in non-small cell lung cancer ENSG00000291971 ENSG00000198793 PMC5333385__F2 Proposed biosynthetic pathway of sex pheromone production in female DBM moths (adapted from [, , ]) ENSG00000026103 PMC4057789__F1 Cross-talk between EpCAM signaling and the Wnt pathway ENSG00000119888 ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC3288148__F1 Three pathways contribute to cellular BH4 levels, the synthesis pathway, the salvage pathway and the recycling pathway ENSG00000228716 ENSG00000116096 PMC7555758__F1 Interplay between neurons and glia in various conditions ENSG00000137033 ENSG00000125538 PMC8145797__F1 Host Factors That Control Mosquito-Borne Viral Infections in Humans and Their Vector ENSG00000172936 ENSG00000168040 ENSG00000143196 ENSG00000123908 PMC6756887__F8 Graphical abstract of the senescence pathway in Idh2-deficient conditions ENSG00000123374 ENSG00000047936 PMC4636224__F6 Dual Action of miR-125b As a Tumor Suppressor and OncomiR-22 Promotes Prostate Cancer Tumorigenesis ENSG00000065361 PMC6232796__F3 mTORC2 in cell metabolism ENSG00000131473 ENSG00000150907 ENSG00000103257 ENSG00000115419 ENSG00000026103 PMC7886702__F5 Molecular and functional profiling of apical versus basolateral small extracellular vesicles derived from primary human proximal tubular epithelial cells under inflammatory conditions ENSG00000183255 ENSG00000112343 ENSG00000169756 ENSG00000163568 ENSG00000178209 ENSG00000166090 ENSG00000276798 ENSG00000267534 ENSG00000076604 ENSG00000180210 ENSG00000111537 ENSG00000134830 ENSG00000115415 ENSG00000104549 ENSG00000140511 ENSG00000132517 ENSG00000006016 PMC7886702__F4 Molecular and functional profiling of apical versus basolateral small extracellular vesicles derived from primary human proximal tubular epithelial cells under inflammatory conditions ENSG00000154451 ENSG00000185215 ENSG00000117228 ENSG00000115415 ENSG00000140968 ENSG00000150907 ENSG00000140511 ENSG00000184371 ENSG00000154127 ENSG00000180644 ENSG00000123908 PMC8918930__F8 Chinese Herbal Extracts Exert Neuroprotective Effect in Alzheimer’s Disease Mouse Through the Dopaminergic Synapse/Apoptosis Signaling Pathway ENSG00000100519 ENSG00000108298 ENSG00000100410 ENSG00000139343 ENSG00000168002 ENSG00000171791 ENSG00000063244 ENSG00000162385 ENSG00000120910 ENSG00000136541 ENSG00000108179 ENSG00000175467 ENSG00000165525 ENSG00000166902 PMC4644296__F3 Androgen receptor activation pathways ENSG00000168036 ENSG00000168610 ENSG00000146648 PMC5833788__F7 NIT1 and TGFBeta-Smad2/3 signalling pathway in colorectal cancer ENSG00000105329 PMC6668582__F1 Urea cycle pathway ENSG00000036473 PMC6514070__F3 Cellular pathways and major players for the induction of the immediate early genes egr (a) and c-jun (b), and downstream targets, with focus on pathways previously linked to learning and memory in honey bees [, , , ] ENSG00000117525 ENSG00000146648 PMC5875170__F2 Regulation of adiposity by mTORC1 ENSG00000177169 ENSG00000155792 ENSG00000167965 PMC8586701__F5 Krill Oil Alleviated Methamphetamine-Induced Memory Impairment via the MAPK Signaling Pathway and Dopaminergic Synapse Pathway ENSG00000142192 ENSG00000138798 ENSG00000177606 ENSG00000164305 ENSG00000149295 PMC8620939__F3 MTOR Pathway in Pluripotent Stem Cells: Lessons for Understanding Cancer Cell Dormancy ENSG00000198793 ENSG00000112561 PMC8620939__F2 MTOR Pathway in Pluripotent Stem Cells: Lessons for Understanding Cancer Cell Dormancy ENSG00000177169 ENSG00000155792 ENSG00000167965 ENSG00000096717 PMC5219787__F4 Hedgehog signaling pathway ENSG00000128602 PMC7138402__F5 Schematic model by which RACK1 promotes the progression of OSCC ENSG00000177575 ENSG00000136869 ENSG00000126353 PMC5219787__F3 Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC5219787__F6 Ezrin pathway ENSG00000163914 ENSG00000026508 PMC5219787__F5 PI3K-AKT-mTOR and RAS-RAF-MEK-ERK pathways PMC3822435__F3 Molecular Pathogenesis of Endometrial and Ovarian Cancer ENSG00000012048 ENSG00000168036 ENSG00000139618 PMC7123827__F4 3 signals of T-helper cell activation ENSG00000134982 PMC7796397__F2 Two major RNA export receptor pathways, nuclear RNA export factor 1 (NXF1)/nuclear transport factor 2-like export 1 (NXT1) and chromosome maintenance protein 1 (CRM1), are shown, and both are dysregulated in cancer ENSG00000047410 ENSG00000099901 ENSG00000124789 ENSG00000101146 ENSG00000132661 ENSG00000147206 ENSG00000153201 ENSG00000183479 ENSG00000213024 PMC8509622__F3 Epoxyeicosatrienoic Acids and Fibrosis: Recent Insights for the Novel Therapeutic Strategies ENSG00000137672 PMC9570193__F8 Alterations of Central Liver Metabolism of Pediatric Patients with Non-Alcoholic Fatty Liver Disease ENSG00000144063 ENSG00000172680 ENSG00000159224 ENSG00000197713 ENSG00000122966 ENSG00000196839 ENSG00000084110 ENSG00000120885 ENSG00000154016 ENSG00000167508 ENSG00000069482 ENSG00000172005 ENSG00000198670 PMC6553645__F3 Roles of mTOR complexes in the kidney: implications for renal disease and transplantation ENSG00000134982 ENSG00000173599 ENSG00000162692 PMC7694322__F1 Melatonin biosynthesis and intracellular signal-transduction pathways activated by stimulation of melatonin specific receptors ENSG00000145321 ENSG00000087250 PMC7125019__F1 MTOR signaling pathway ENSG00000100811 ENSG00000177169 ENSG00000163914 ENSG00000118515 ENSG00000155792 ENSG00000167965 PMC3174986__F3 Plasmodium falciparum-Infected Erythrocytes and IL-12/IL-18 Induce Diverse Transcriptomes in Human NK Cells: IFNA/B Pathway versus TREM Signaling ENSG00000068079 ENSG00000213928 ENSG00000111537 ENSG00000115415 ENSG00000033800 ENSG00000185745 ENSG00000125347 ENSG00000230034 PMC8333067__F6 Pattern recognition receptors in health and diseases ENSG00000183735 ENSG00000088888 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000164342 PMC11763799__F1 EGFR signaling pathway scheme ENSG00000157764 ENSG00000138798 ENSG00000198793 ENSG00000136997 ENSG00000168610 ENSG00000146648 PMC11763799__F3 RAS triggering processes in cancer cells ENSG00000135446 ENSG00000198793 ENSG00000136997 ENSG00000163734 ENSG00000168310 ENSG00000105810 ENSG00000112715 PMC9496891__F4 Development and Challenges of Diclofenac-Based Novel Therapeutics: Targeting Cancer and Complex Diseases ENSG00000124102 ENSG00000116717 ENSG00000166278 PMC4981729__F1 Proposed regulation of HSC quiescence by paternally imprinted DMRs ENSG00000198793 PMC5729527__F2 Scheme of reported cross-talk between core Hippo pathway components and wt (left) or mutant (right) p53 ENSG00000068028 ENSG00000150457 ENSG00000096717 ENSG00000131023 PMC5729527__F1 Simplified version of the key factors within the Hippo signaling pathway ENSG00000150457 ENSG00000131023 PMC7376204__F6 Significantly enriched KEGG pathways for a down-regulated gene set after 24 h CM03 treatment ENSG00000198793 ENSG00000155792 ENSG00000285069 PMC3397482__F2 Map of the VEGF signaling pathway (as an example of an important target in cancer therapy) obtained from KEGG is shown ENSG00000002330 ENSG00000291971 PMC6937575__F5 The CD38/cADPR/NAADP-signaling pathway PMC9179506__F1 Insights into the Possible Molecular Mechanisms of Resistance to PARP Inhibitors ENSG00000012048 PMC4307931__F1 Collagen XIA1 in cancer promotion ENSG00000149968 ENSG00000100985 PMC3397482__F4 Cytoscape is an open-source bioinformatics software platform for visualizing molecular interaction networks and integrating these networks with other state data ENSG00000108557 PMC3418756__F6 Immune activation in the GBS UTI transcriptome comprises prominent cytokine-cytokine receptor signaling ENSG00000169245 ENSG00000115008 ENSG00000147168 ENSG00000115415 ENSG00000138755 ENSG00000110324 ENSG00000026103 PMC3422477__F1 Apoptosis affects cell signaling pathways that control lipid synthesis and energy metabolism ENSG00000149311 ENSG00000131473 ENSG00000169710 ENSG00000078237 PMC5588661__F1 Action of metformin on cancer ENSG00000198793 ENSG00000169710 PMC2245955__F5 Gene expression changes observed in Sema3A signaling pathway ENSG00000221866 ENSG00000131462 ENSG00000070831 ENSG00000151640 ENSG00000243156 ENSG00000241553 ENSG00000082684 ENSG00000167680 ENSG00000187764 ENSG00000135596 ENSG00000111229 ENSG00000106683 ENSG00000182511 ENSG00000169750 ENSG00000149269 ENSG00000133816 ENSG00000163017 ENSG00000092421 ENSG00000118257 ENSG00000198910 ENSG00000143632 ENSG00000130827 ENSG00000114554 ENSG00000166342 ENSG00000173156 ENSG00000135622 ENSG00000168758 ENSG00000106299 ENSG00000108423 ENSG00000162704 ENSG00000137872 ENSG00000067900 ENSG00000288455 ENSG00000170381 ENSG00000183785 ENSG00000075223 ENSG00000153993 ENSG00000172602 ENSG00000010810 ENSG00000185033 ENSG00000076356 ENSG00000075213 PMC3855473__F2 Tax-specific noncanonical NFKB pathway ENSG00000104856 ENSG00000131323 ENSG00000127191 PMC3855473__F1 Canonical NFKB activation by TCR/CD28 and HTLV1 Tax ENSG00000127445 ENSG00000162924 PMC8147357__F1 mTOR Signaling in Metabolic Stress Adaptation ENSG00000164327 PMC7756126__F5 Usage of lymphoma B-cell receptor (BCR) antigens for targeting lymphoma ENSG00000186716 ENSG00000167100 ENSG00000105656 PMC11583678__F4 Elucidated mechanism of OMVs ENSG00000134982 ENSG00000172936 PMC8915915__F2 Centrality of Myeloid-Lineage Phagocytes in Particle-Triggered Inflammation and Autoimmunity ENSG00000102871 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000127191 PMC9179423__F3 Bottom-Up Approach to the Discovery of Clinically Relevant Biomarker Genes: The Case of Colorectal Cancer ENSG00000002330 ENSG00000134982 ENSG00000095002 ENSG00000164305 ENSG00000122008 PMC7177420__F1 Harmful effects and mechanisms of alcohol ENSG00000108691 ENSG00000125538 ENSG00000131095 PMC3445042__F7 The role of Wnt signaling in hypothalamic progenitor differentiation ENSG00000077279 ENSG00000131095 ENSG00000134595 ENSG00000114315 PMC7051217__F3 Complement factor I deficiency PMC7600397__F4 DNA damage response pathway (DDR) ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 PMC9699766__F7 lncRNA HHIP-AS1/HHIP modulates osteogenic differentiation of BM-MSCs by regulating Hedgehog signaling pathway ENSG00000164161 ENSG00000164690 ENSG00000128602 PMC3325426__F1 The miRNA biosynthesis pathway from the nucleus to the cytosol ENSG00000100697 ENSG00000124571 ENSG00000113360 PMC7216814__F7 Network regulation map of downregulated miRNAs, SOX2, and other genes in the platinum drug resistance pathway ENSG00000132906 ENSG00000149311 ENSG00000140992 ENSG00000117020 ENSG00000113318 ENSG00000131747 ENSG00000120868 ENSG00000171791 ENSG00000168040 PMC10917885__F1 UST treatments specifically target the IL-12/IL-23 signaling pathway ENSG00000162594 ENSG00000138378 ENSG00000105397 ENSG00000168610 ENSG00000111962 PMC3666582__F7 IDENTIFICATION AND DESCRIPTION OF A NOVEL MURINE MODEL FOR POLYTRAUMA AND SHOCK ENSG00000105397 ENSG00000175104 ENSG00000168610 PMC5063588__F9 How Thbs4 functions as an intracellular regulator of muscle cellular attachment and membrane stability ENSG00000042832 ENSG00000113296 PMC3149005__F6 Summary of the UPR pathway in rotavirus infected cells ENSG00000128272 PMC9609401__F3 Simplifying the B Complex: How Vitamins B6 and B9 Modulate One Carbon Metabolism in Cancer and Beyond ENSG00000228716 PMC9609401__F1 Simplifying the B Complex: How Vitamins B6 and B9 Modulate One Carbon Metabolism in Cancer and Beyond ENSG00000151224 PMC8011569__F4 Analysis of gene pathways for MENT, LH alone or in combination (MENT+LH) to regulate steroidogenesis ENSG00000133835 ENSG00000161513 ENSG00000137714 ENSG00000203857 PMC9403273__F1 Inflammation in hematopoiesis and bone marrow failure: What can we learn from mouse models? ENSG00000168062 ENSG00000239732 ENSG00000102871 ENSG00000136869 ENSG00000168040 ENSG00000168404 ENSG00000285379 ENSG00000164342 PMC3311998__F6 Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate ENSG00000062485 PMC9358977__F2 Immune-mediated inflammatory diseases with chronic excess of serum interleukin-18 ENSG00000162711 ENSG00000070831 ENSG00000091106 PMC6675034__F4 Full candidate pathway that represents molecular drivers of tumorigenesis in the sarcoma of patient 1 ENSG00000175868 ENSG00000182944 ENSG00000198793 ENSG00000131747 ENSG00000110680 ENSG00000087586 ENSG00000105647 ENSG00000106688 ENSG00000154447 ENSG00000073756 ENSG00000187840 ENSG00000157557 ENSG00000117020 ENSG00000089685 ENSG00000123268 PMC2807132__F2 p38 signaling to the chromatin in muscle progenitor cells ENSG00000070831 ENSG00000189403 ENSG00000291761 PMC7072222__F2 Nucleolar surveillance pathway PMC6935412__F3 Increased IFNB enhanceosome components in lupus B cells ENSG00000239732 ENSG00000164430 ENSG00000115415 ENSG00000186716 ENSG00000172936 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC3688817__F8 PPARB Regulates Liver Regeneration by Modulating Akt and E2f Signaling ENSG00000131473 ENSG00000135446 ENSG00000123374 PMC9285505__F1 Hydrogen sulphide in liver glucose/lipid metabolism and non‐alcoholic fatty liver disease PMC6698416__F3 Challenges in deconstructing multicomponent cell responses triggered as a result of uncontrolled RES-exposure ENSG00000168036 ENSG00000079999 PMC1169236__F2 Metabolic reconstructions of the polyamine pathway based upon pam and sam analyses of poor-prognosis human NE tumors ENSG00000116649 ENSG00000102172 PMC2605486__F4 Olig2 and the transcription factor network controlling motor neuron differentiation ENSG00000125285 ENSG00000182968 ENSG00000205927 ENSG00000134595 ENSG00000177508 ENSG00000016082 ENSG00000159556 PMC4128044__F2 MTOR pathway as a therapeutic target PMC5889750__F10 The Transcriptional Response of Skin to Fluorescent Light Exposure in Viviparous (Xiphophorus) and Oviparous (Danio, Oryzias) Fishes ENSG00000244731 ENSG00000166278 ENSG00000182326 PMC2605486__F3 Progressive changes in progenitor cells during motor neuron development ENSG00000125285 ENSG00000182968 ENSG00000125398 ENSG00000005513 ENSG00000143842 ENSG00000205927 ENSG00000164690 ENSG00000134595 ENSG00000100146 ENSG00000016082 ENSG00000159556 PMC4128044__F1 MTOR pathway is a central regulator of cellular processes ENSG00000118515 ENSG00000155792 ENSG00000186654 PMC5482185__F5 Diverse cellular functions of arrestin scaffolds ENSG00000168036 ENSG00000171791 PMC4749494__F5 The effects of extracellular CypA and MM284 in experimental BA ENSG00000137673 ENSG00000157150 PMC8664591__F1 Appetite Regulation of TLR4-Induced Inflammatory Signaling ENSG00000198576 ENSG00000115138 ENSG00000170893 ENSG00000166603 PMC4826392__F3 The dynamics of TET-mediated cytosine oxidation and its impact on DNA methylation patterns on regulatory elements in vivo ENSG00000187605 ENSG00000138336 ENSG00000139372 PMC4826392__F2 Pathways of DNA demethylation mediated by TET enzymes ENSG00000187605 ENSG00000138336 ENSG00000145321 ENSG00000139372 ENSG00000276043 PMC7551039__F1 Immune checkpoint-mediated T-cell inactivation ENSG00000089692 ENSG00000291603 ENSG00000181847 ENSG00000134982 ENSG00000163599 PMC9230919__F1 Folate Related Pathway Gene Analysis Reveals a Novel Metabolic Variant Associated with Alzheimer’s Disease with a Change in Metabolic Profile ENSG00000228716 ENSG00000100714 ENSG00000116984 PMC5398990__F3 Schematic overview of underlying pathophysiology and targeted therapies in neurofibromatosis 1 (NF1)-associated malignant peripheral nerve sheath tumors (MPNSTs) ENSG00000198793 ENSG00000087586 ENSG00000196712 PMC8065873__F2 Anti-metastatic mechanisms of herbal medicine in colorectal cancer: Herbal medicines suppress angiogenesis, migration and invasion via inactivation of diverse HIF-1A pathways ENSG00000108691 ENSG00000107562 ENSG00000291971 ENSG00000168036 ENSG00000112715 ENSG00000121807 ENSG00000146648 ENSG00000121966 ENSG00000150630 PMC8065873__F1 Recent Advances in Anti-Metastatic Approaches of Herbal Medicines in 5 Major Cancers: From Traditional Medicine to Modern Drug Discovery ENSG00000188486 ENSG00000070831 ENSG00000291971 ENSG00000132646 ENSG00000198793 ENSG00000123374 ENSG00000185591 ENSG00000112715 ENSG00000168610 ENSG00000121966 ENSG00000150630 PMC5612509__F1 Complement-mediated haemolysis in chronic cold agglutinin disease and cold agglutinin syndrome ENSG00000166278 PMC8944968__F3 Circular RNA ITCH: An Emerging Multifunctional Regulator ENSG00000078747 ENSG00000134982 ENSG00000168036 PMC8065873__F5 Recent Advances in Anti-Metastatic Approaches of Herbal Medicines in 5 Major Cancers: From Traditional Medicine to Modern Drug Discovery ENSG00000186810 ENSG00000197713 ENSG00000170558 ENSG00000125538 ENSG00000126353 ENSG00000162692 ENSG00000168610 ENSG00000146648 ENSG00000122194 ENSG00000062485 PMC8065873__F4 Anti-metastatic mechanisms of herbal medicine in liver cancer: Herbal medicines interrupt signaling transduction and EMT cascades related with cancer cell migration and metastasis ENSG00000143248 ENSG00000198793 ENSG00000168036 ENSG00000168610 ENSG00000121966 PMC8065873__F3 Anti-metastatic mechanisms of herbal medicine in gastric cancer: When it comes to ROS, it has double-edged aspects in anti-tumor efficacy and mechanisms ENSG00000070831 ENSG00000170558 ENSG00000167468 ENSG00000005381 PMC11629574__F8 Schematic diagram showing the yes-associated protein 1 (YAP1) as a critical molecular pattern for diabetic kidney disease (DKD) ENSG00000163739 ENSG00000158828 ENSG00000124875 ENSG00000150457 ENSG00000131023 PMC2648620__F2 Insights into the Roles of Gut Microbes in Obesity ENSG00000108691 ENSG00000125538 ENSG00000177606 ENSG00000172936 ENSG00000150455 ENSG00000168610 PMC4974519__F1 The induction of ER stress and UPR during coronavirus infection ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8521937__F4 Impaired antioxidant KEAP1-NRF2 system in amyotrophic lateral sclerosis: NRF2 activation as a potential therapeutic strategy ENSG00000178573 ENSG00000100387 ENSG00000285246 ENSG00000079999 PMC2733092__F4 Intersection sets of the differentially expressed miRNAs constitute complex interaction networks.A Venn diagram illustrating the production of intersection sets from three miRNA target prediction algorithms ENSG00000288283 ENSG00000125398 ENSG00000136997 ENSG00000129152 ENSG00000112715 ENSG00000132170 ENSG00000110693 PMC6604516__F7 Graphical signalling pathway of the effect of APPBP2 on NSCLC via PPM1D and SPOP.The blue lines indicate the activation of the targets according to our experiments or published researches ENSG00000062725 ENSG00000135446 ENSG00000121067 PMC3394800__F5 Developmental Changes in the Metabolic Network of Snapdragon Flowers ENSG00000105251 ENSG00000197429 ENSG00000062485 PMC3394800__F4 Developmental Changes in the Metabolic Network of Snapdragon Flowers ENSG00000197713 PMC4026703__F1 Schematic diagram showing the central role of the BMP6-HJV-SMAD signaling pathway in hepcidin regulation and the proposed interaction with other hepcidin regulators ENSG00000019991 ENSG00000170365 ENSG00000010704 ENSG00000106327 ENSG00000187045 ENSG00000138798 ENSG00000128791 ENSG00000198793 ENSG00000130513 PMC7151129__F1 The retinoic acid signalling pathway during development ENSG00000121039 ENSG00000162496 PMC3394800__F7 Developmental Changes in the Metabolic Network of Snapdragon Flowers ENSG00000146733 ENSG00000062485 PMC8920937__F8 TMBIM1 promotes proliferation and attenuates apoptosis in glioblastoma cells by targeting the p38 MAPK signalling pathway ENSG00000002330 ENSG00000135926 ENSG00000164305 PMC3840081__F2 Estrogen-induced ER-mediated pathways of vascular relaxation ENSG00000145321 PMC3108474__F2 Membrane type-MMPs regulate vascular cell signaling in cancer ENSG00000087245 ENSG00000291971 ENSG00000113070 ENSG00000198793 ENSG00000100985 PMC9228236__F4 Assessing Gene Expression Related to Cisplatin Resistance in Human Oral Squamous Cell Carcinoma Cell Lines ENSG00000173156 ENSG00000170558 ENSG00000198517 ENSG00000158887 ENSG00000026508 ENSG00000113360 PMC3632219__F7 Proposed roles of PLCB1 in degradation of endocannabinoids at implantation sites ENSG00000117480 ENSG00000182621 PMC9428582__F2 Targeting O-GlcNAcylation to overcome resistance to anti-cancer therapies ENSG00000147162 ENSG00000072274 ENSG00000167996 ENSG00000120885 ENSG00000112759 ENSG00000146648 ENSG00000280548 ENSG00000013375 PMC9084533__F8 Role of OPTN on myogenesis during muscle regeneration ENSG00000122180 ENSG00000123240 ENSG00000134982 ENSG00000168036 PMC2963118__F2 HRS cell and its cellular microenvironment ENSG00000111537 ENSG00000115415 PMC3736507__F2 Schematic diagram showing that cartilage matrix homeostasis is adjusted dynamically by TGFB signaling pathway ENSG00000170365 PMC5641113__F9 Genome-wide functional analysis on the molecular mechanism of specifically biosynthesized fluorescence Eu complex ENSG00000177455 ENSG00000124102 ENSG00000103479 ENSG00000157404 ENSG00000197872 ENSG00000002330 ENSG00000147168 ENSG00000186716 ENSG00000198793 ENSG00000091879 ENSG00000065243 PMC8059100__F8 Schematic presentation of possible mechanism of VERU-111 in CxCa ENSG00000002330 ENSG00000135446 ENSG00000168610 PMC6216000__F1 Radiation and tyrosine kinase inhibitor resistance ENSG00000198793 ENSG00000146648 PMC4714660__F1 Human dendritic cell (DC) response to Toll‐like receptor (TLR)2/3 adjuvants ENSG00000174123 ENSG00000123685 ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC4383269__F9 Human Papillomavirus 16E6 and NFX1-123 Potentiate Notch Signaling and Differentiation without Activating Cellular Arrest ENSG00000148400 ENSG00000203782 ENSG00000273529 ENSG00000114315 PMC11532153__F3 Functions of p120-catenin in physiology and diseases ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC9646812__F4 Transcriptomic profiling analysis to identify genes associated with PA biosynthesis and insolubilization in the late stage of fruit development in C-PCNA persimmon ENSG00000062485 PMC3219972__F3 Effect of carbon exchange and reversibility constraints ENSG00000108582 ENSG00000196839 PMC7484971__F8 KEGG enrichment graph: miRNA-4534 is involved in the FOXO signaling pathway ENSG00000087095 ENSG00000171105 ENSG00000138798 ENSG00000127528 ENSG00000162924 ENSG00000168610 ENSG00000047932 ENSG00000145604 ENSG00000149311 ENSG00000123374 ENSG00000145782 ENSG00000146648 ENSG00000168685 PMC5664079__F3 PDK1 and the Salvador/Warts/Hippo (SWH) pathway ENSG00000213658 PMC2094129__F2 Respective balance between Gi- and Gs-dependent signalling pathways and their roles in the modification of FcARI-mediated mast cell degranulation ENSG00000010810 ENSG00000198670 ENSG00000010671 PMC5664079__F1 Major signaling pathways in chemoresistance and PDK1 implication ENSG00000147649 ENSG00000110931 PMC7110753__F3 Hypothesized dauer signaling during N ENSG00000157933 ENSG00000196839 ENSG00000118515 ENSG00000189430 PMC10779870__F11 KEGG TNFA signaling and its association with the PI3K-AKT signaling pathway ENSG00000131323 ENSG00000127191 PMC4240841__F1 Proposed model of Ostf1 in fishes ENSG00000067900 PMC7956578__F2 Impact of hypoxia pathway proteins on immune cells and cancer stem cells, and their impact on the development of the tumor ENSG00000019991 ENSG00000138798 PMC10779870__F13 Proposed molecular effects of fucoxanthin through modulation of genes and proteins of the PI3K-AKT signaling pathway in TNF-Alpha-stimulated MDA-MB-231 and MDA-MB-468 cells ENSG00000005882 ENSG00000150907 ENSG00000169047 ENSG00000150455 ENSG00000187840 PMC4714660__F4 Cell death pathway in tumor cells ENSG00000105664 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000247077 ENSG00000164342 PMC7218030__F3 Partial action pathways of H2S donors and their derivatives on TNBC ENSG00000132906 ENSG00000164379 ENSG00000198793 ENSG00000168036 ENSG00000164305 PMC6400837__F1 Notch pathway promotes drug resistance by regulating cancer cell survival, glycolytic switch and cancer stem cells ENSG00000005882 ENSG00000103222 ENSG00000213614 ENSG00000171791 ENSG00000184916 ENSG00000168610 ENSG00000074800 ENSG00000168214 ENSG00000128917 ENSG00000136997 ENSG00000114315 ENSG00000159399 ENSG00000152556 PMC8213345__F3 Interplay of Forces and the Immune Response for Functional Tendon Regeneration ENSG00000168036 ENSG00000001626 ENSG00000108821 ENSG00000000005 PMC3362209__F1 RIP-1 in programmed necrosis ENSG00000157625 ENSG00000083799 ENSG00000168040 ENSG00000115718 PMC5511947__F1 The downstream signaling cascade initiated by a hypoxic microenvironment ENSG00000168283 ENSG00000169554 ENSG00000119888 ENSG00000122691 ENSG00000170558 ENSG00000288335 ENSG00000026508 ENSG00000118777 ENSG00000121966 PMC7349551__F1 Wingless and Int-1 (WNT)/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC11715087__F9 Working model summarizing key conclusions from this study ENSG00000173805 ENSG00000092621 ENSG00000213995 PMC9266842__F2 Immunomodulatory Properties of PI3K/AKT/mTOR and MAPK/MEK/ERK Inhibition Augment Response to Immune Checkpoint Blockade in Melanoma and Triple-Negative Breast Cancer ENSG00000145604 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC9664149__F6 Glutathione: A Samsonian life-sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation ENSG00000183691 ENSG00000005381 ENSG00000132693 PMC3393131__F1 Wnt/Beta-catenin signaling in T cell immunity and cancer immunotherapy ENSG00000274382 ENSG00000281324 ENSG00000162337 ENSG00000182568 ENSG00000134982 ENSG00000168036 ENSG00000167074 PMC4166520__F1 ATX-LPA Receptor Axis in Inflammation and Cancer ENSG00000090402 ENSG00000184661 ENSG00000198670 PMC9664149__F8 Glutathione: A Samsonian life-sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation ENSG00000130234 ENSG00000005381 ENSG00000132693 PMC6433792__F1 Phosphodiesterases (PDEs) in the pituitary gland: After stimulation of somatotroph cells via GHRH, the G protein coupled receptor is activated, which causes a conformational change of the receptor ENSG00000110711 ENSG00000065989 ENSG00000291972 ENSG00000113448 PMC3573097__F7 Kinome-Wide RNAi Screen in Drosophila Glia Reveals That the RIO Kinases Mediate Cell Proliferation and Survival through TORC2-Akt Signaling in Glioblastoma ENSG00000124784 ENSG00000146648 ENSG00000058729 PMC3949429__F2 Two major signaling pathways activated by HBV and HCV in hepatocarcinogenesis ENSG00000002330 ENSG00000291971 ENSG00000134982 ENSG00000169047 ENSG00000168036 PMC9297740__F1 PARP Inhibitors in Glioblastoma and Perceiving Challenges as Well as Strategies for Successful Clinical Development ENSG00000170430 ENSG00000095002 PMC4083841__F1A Beta-Thalassemia and Polycythemia vera: targeting chronic stress erythropoiesis ENSG00000187266 PMC9550229__F2 Screening and validation of nickel ion cytotoxicity biomarkers based on transcriptomic and proteomic technology ENSG00000213658 ENSG00000184371 ENSG00000160293 ENSG00000084774 PMC4674888__F9 Development WNT signaling pathway Part 1 ENSG00000145604 ENSG00000100387 ENSG00000134982 ENSG00000168036 ENSG00000196628 PMC4674888__F8 Development Hedgehog Signaling which is the top scored pathway map in MetaCore enrichment analysis results ENSG00000064309 ENSG00000165115 ENSG00000105401 ENSG00000121067 ENSG00000168036 ENSG00000150459 ENSG00000145604 ENSG00000180447 ENSG00000106571 ENSG00000100387 ENSG00000144857 ENSG00000154309 ENSG00000139549 ENSG00000133961 ENSG00000164690 ENSG00000163501 PMC8047077__F7 IFI6 mediated inhibition of HBV replication and gene expression ENSG00000115415 PMC5880536__F2 Gut microbiota and IBD: causation or correlation? ENSG00000111537 ENSG00000125538 ENSG00000106546 PMC4132784__F7 Mechanism by which the PTEN-PI3K-AKT-MDM2 signaling axis exerts control over HIF1A degradation in cytoplasm under hypoxic conditions via the MDM2 E3 ligase and 26 S proteasome ENSG00000124102 ENSG00000134086 ENSG00000100387 PMC11008728__F2 Fine-tuning tumor- and allo-immunity: advances in the use of immune checkpoint inhibitors in kidney transplant recipients ENSG00000169248 ENSG00000169245 ENSG00000134982 ENSG00000138755 PMC8198195__F5 Resolving the Contradictory Functions of Lysine Decarboxylase and Butyrate in Periodontal and Intestinal Diseases ENSG00000087299 PMC11490609__F4 MAPK pathway activation in zccs1703 ENSG00000157764 ENSG00000135446 ENSG00000128052 ENSG00000115904 ENSG00000105810 ENSG00000112715 ENSG00000077782 ENSG00000196712 PMC10779157__F3 SHP-1-mediated inhibition of the JAK/STAT signaling pathway ENSG00000105397 ENSG00000115415 ENSG00000187266 PMC8147772__F3 Control of Macrophage Inflammation by P2Y Purinergic Receptors ENSG00000115415 ENSG00000172936 ENSG00000136869 PMC8147772__F2 Control of Macrophage Inflammation by P2Y Purinergic Receptors ENSG00000172936 ENSG00000136869 PMC3602989__F2 Leptin and cancer: Pathogenesis and modulation ENSG00000160741 PMC8294041__F8 Cancer Preventive and Therapeutic Potential of Banana and Its Bioactive Constituents: A Systematic, Comprehensive, and Mechanistic Review ENSG00000138798 ENSG00000162772 ENSG00000146648 PMC5739444__F7 SIRT2 gene has a classic SRE element, is a downstream target of serum response factor and is likely activated during serum stimulation ENSG00000163914 ENSG00000283100 PMC6585406__F1 OAS/RNase L pathway ENSG00000089127 ENSG00000135114 ENSG00000111331 ENSG00000135828 PMC8534193__F1 Emerging Influences of Alpha-Fetoprotein in the Tumorigenesis and Progression of Hepatocellular Carcinoma ENSG00000178764 ENSG00000081051 PMC6888217__F3 Extracellular ADO on subsets of macrophages ENSG00000177575 ENSG00000129226 PMC6888217__F1 Extracellular and intracellular (canonical and non-canonical) adenosinergic pathways ENSG00000196839 ENSG00000197594 ENSG00000087842 PMC3196095__F6 Proposed model ENSG00000170458 ENSG00000136869 PMC2605641__F2 Nrf2-ARE Pathway: An Indicator and Modulator of Oxidative Stress in Neurodegeneration ENSG00000181019 ENSG00000023909 ENSG00000105227 PMC9058032__F5 Ba Zhen Tang Delaying Skin Photoaging Based on Network Pharmacology and Molecular Docking ENSG00000182511 ENSG00000167207 ENSG00000157227 ENSG00000007908 ENSG00000131323 ENSG00000128342 ENSG00000115718 ENSG00000127191 ENSG00000127948 PMC4125705__F4 Phenylpropanoid biosynthetic pathway in Ocimum sps ENSG00000062485 ENSG00000084774 PMC3610375__F1 The Role of Vitamin D Deficiency in the Incidence, Progression, and Complications of Type 1 Diabetes Mellitus ENSG00000113520 PMC3969997__F7 The hypothetical signaling pathway in pathological angiogenesis regulated by interactions of activated VEGFR2 and EPOR ENSG00000187266 ENSG00000112715 ENSG00000168610 PMC2542903__F6 Proposed EphB2 signaling network ENSG00000135655 ENSG00000162733 ENSG00000107338 ENSG00000069869 ENSG00000128512 ENSG00000138443 ENSG00000143322 ENSG00000288461 PMC9226676__F2 Sertoli Cell-Germ Cell Interactions Within the Niche: Paracrine and Juxtacrine Molecular Communications PMC5766282__F12 Novel Role of the Nociceptin System as a Regulator of Glutamate Transporter Expression in Developing Astrocytes ENSG00000198793 ENSG00000105639 PMC2995293__F2 Immune and central nervous systems interact and contribute to the etiology and pathophysiology of cytokine-induced depression ENSG00000125538 ENSG00000015285 ENSG00000132693 PMC12165645__F1 Simplified overview of ISGs and their actions in kidney diseases ENSG00000187608 ENSG00000089127 ENSG00000185745 ENSG00000135605 ENSG00000172183 PMC7511443__F4 MC5R signaling pathways ENSG00000166819 ENSG00000115415 PMC12165645__F2 Therapeutic agents targeting ISGs ENSG00000213928 ENSG00000187608 ENSG00000276561 ENSG00000172183 PMC4153031__F2 The hypothetical estrogen-induced signaling pathway in neurons ENSG00000142192 PMC8866817__F4 CD3+CD4-CD8- (Double-Negative) T Cells in Inflammation, Immune Disorders and Cancer ENSG00000168040 ENSG00000026103 PMC3386525__F3 The signalling transduction pathways involving the tuberous sclerosis proteins, hamartin and tuberin ENSG00000198793 ENSG00000163914 PMC7916982__F9 Iso-Alpha-acids can exert anti-inflammatory activity by inhibiting the NF-kB pathway by acting on several kinases involved upstream and downstream of the signal transduction ENSG00000125538 ENSG00000172005 ENSG00000172936 ENSG00000102010 ENSG00000010671 PMC7933481__F1 Anti-inflammatory effects of increased global SUMOylation in the intestine ENSG00000162711 ENSG00000107562 ENSG00000161921 ENSG00000138755 ENSG00000197272 ENSG00000112115 ENSG00000115009 PMC2696288__F7 Protein Acetylation Microarray Reveals NuA4 Controls Key Metabolic Target Regulating Gluconeogenesis ENSG00000173599 ENSG00000096717 ENSG00000124253 PMC4464175__F5 Lipid biosynthetic pathways and interactions of phospholipid synthases and proteins involved in cell division ENSG00000065357 ENSG00000226275 ENSG00000136267 ENSG00000198670 ENSG00000184207 PMC6036613__F3 NFKB pathway induced by LaW37 in Caco-2 cells ENSG00000104856 ENSG00000226275 ENSG00000291603 ENSG00000163235 ENSG00000138798 ENSG00000060237 ENSG00000173039 ENSG00000197943 ENSG00000111321 ENSG00000198286 PMC3075645__F8 DNA damage-triggered activation of SAPK/JNK at late times following cisplatin treatment ENSG00000149311 ENSG00000175054 ENSG00000163914 ENSG00000136936 ENSG00000139618 PMC6722208__F1 Circadian regulation of hepatic gluconeogenesis illustrates an example of bi-directional regulation between clock genes and metabolism ENSG00000105835 ENSG00000150907 ENSG00000096717 ENSG00000124253 PMC7140515__F1 Crucial signaling pathways in CCA metabolism ENSG00000171720 ENSG00000150907 ENSG00000175567 ENSG00000096717 ENSG00000131828 ENSG00000283100 PMC5343750__F1 Are Circulating MicroRNAs Peripheral Biomarkers for Alzheimer’s Disease? ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC10583183__F11 Mechanism that HRF prompts pyroptosis via CaSR/NLRP3/caspase1 signaling pathway under MI/R conditions ENSG00000278718 ENSG00000162711 ENSG00000036828 PMC3593087__F1 Pro-osteoblastogenic signal transduction by insulin and IGF1 receptors PMC3593087__F3 Cross-talk between insulin/IGF-1, BMP2, and Wnt signaling pathways ENSG00000170365 ENSG00000029559 ENSG00000134982 ENSG00000169047 ENSG00000168036 PMC7180223__F1 Gene ontology (GO) analysis of LOAD risk factors reveals the enrichment of genes in the trafficking pathway ENSG00000198796 ENSG00000108798 ENSG00000203710 ENSG00000166924 ENSG00000109684 ENSG00000120885 ENSG00000137845 ENSG00000138613 ENSG00000066336 ENSG00000198087 ENSG00000158859 ENSG00000103510 ENSG00000163666 ENSG00000073712 ENSG00000073921 ENSG00000140090 ENSG00000137642 ENSG00000284816 ENSG00000149534 ENSG00000281614 ENSG00000078487 ENSG00000120899 ENSG00000087589 ENSG00000161929 ENSG00000110077 PMC2945784__F2 Cancer signaling pathways affected within the tumor ENSG00000140992 ENSG00000167941 ENSG00000138798 ENSG00000198793 ENSG00000115904 ENSG00000141564 ENSG00000171119 ENSG00000146648 ENSG00000167034 ENSG00000139687 ENSG00000197461 PMC10556387__F2 Neuroprotection targeting to signal transduction of apoptosis, necroptosis, and autophagy in ischemic stroke ENSG00000092439 ENSG00000126775 ENSG00000137275 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC10556387__F1 Neuroprotection targeted to oxidative stress and induced mitochondrial dysfunction and ferroptosis in ischemic stroke ENSG00000167468 ENSG00000111684 ENSG00000079999 PMC3356304__F6 Personalized Pathway Enrichment Map of Putative Cancer Genes from Next Generation Sequencing Data ENSG00000146648 PMC4055840__F5 Hypothetical model illustrating possible molecular mechanisms underlying the action of the glucocorticoid receptor in the excitation-inhibition balance in NPCs PMC8445921__F5 Persistent hyperammonia and altered concentrations of urea cycle metabolites in a 5-day swine experiment of sepsis PMC4344782__F11 Overlapping Alzheimer-related protein association network of AD-iPS5 neurons and of AD-iPS26B neurons ENSG00000142192 ENSG00000112695 ENSG00000073578 ENSG00000131495 ENSG00000179091 ENSG00000143933 ENSG00000004779 ENSG00000165264 ENSG00000178127 ENSG00000267855 ENSG00000136521 ENSG00000127184 ENSG00000131174 ENSG00000151366 ENSG00000189043 ENSG00000099795 ENSG00000119013 PMC8543024__F3 Adenomyosis pathogenesis: insights from next-generation sequencing PMC4344782__F10 Alzheimer-related protein association network in AD-iPS26B neurons ENSG00000142192 ENSG00000169021 ENSG00000112695 ENSG00000073578 ENSG00000131495 ENSG00000184983 ENSG00000179091 ENSG00000159593 ENSG00000126267 ENSG00000143933 ENSG00000010256 ENSG00000004779 ENSG00000165264 ENSG00000178127 ENSG00000267855 ENSG00000136521 ENSG00000127184 ENSG00000131174 ENSG00000151366 ENSG00000189043 ENSG00000099795 ENSG00000119013 PMC3140692__F3 Hypoxia regulates other critical pathways that impact tumor progression in a HIF-independent fashion ENSG00000144895 ENSG00000140464 PMC5524075__F7 Interleukin (IL)‐13RA1 in myocardial metabolism ENSG00000134982 ENSG00000173599 ENSG00000172005 ENSG00000062485 PMC3757391__F1 Maintainance of DNA Methylation ENSG00000149311 ENSG00000175054 ENSG00000138336 ENSG00000088305 ENSG00000139372 ENSG00000129071 ENSG00000168040 PMC9243104__F7 Graphical abstract of WASp:RPA alliance in genome stability ENSG00000015285 ENSG00000143971 PMC5817862__F2 TKIs inhibit TKs-mediated signaling pathway ENSG00000198793 PMC8081290__F3 Integrated working model of key metabolic signaling axes in macrophages (Mфs) during ischemic organ injury and repair ENSG00000162711 ENSG00000153208 ENSG00000135218 ENSG00000122966 ENSG00000125538 ENSG00000198793 ENSG00000136869 ENSG00000026103 PMC8944338__F4 Multi-protein complexes contribute to the Stimuli-Sensing Channels intracellular signaling pathway ENSG00000104321 ENSG00000136295 ENSG00000124564 ENSG00000109572 ENSG00000141540 ENSG00000070985 ENSG00000166278 ENSG00000276537 ENSG00000103249 ENSG00000196689 ENSG00000133115 PMC8944338__F3 Protein-protein interaction network for the AGE-RAGE pathway ENSG00000165197 ENSG00000070831 ENSG00000105329 ENSG00000050748 ENSG00000105647 ENSG00000171791 ENSG00000112715 ENSG00000121879 ENSG00000178726 ENSG00000164305 ENSG00000117525 ENSG00000125538 ENSG00000166501 ENSG00000108821 ENSG00000124181 ENSG00000101333 ENSG00000087245 ENSG00000115008 ENSG00000109320 ENSG00000086991 ENSG00000173039 ENSG00000137193 ENSG00000007908 ENSG00000168610 ENSG00000161714 ENSG00000117020 ENSG00000108691 ENSG00000138193 ENSG00000185386 ENSG00000115415 ENSG00000067606 ENSG00000188130 ENSG00000162692 ENSG00000171608 ENSG00000131196 ENSG00000150630 PMC5362340__F1 Kinase signaling and targeted therapy for primary myelofibrosis ENSG00000117400 ENSG00000149269 ENSG00000087586 ENSG00000168610 PMC3258586__F1 PI3K pathway activated by EGF-stimulated EGFR or by the constitutively activated EGFRvIII ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC10979751__F3 Macrophages in osteosarcoma cell proliferation and metastasis ENSG00000163235 ENSG00000138798 ENSG00000118520 ENSG00000168610 PMC10957566__F2 Protective effect of the Notch signaling pathway on B cells under irradiation exposure ENSG00000140564 ENSG00000090402 ENSG00000196092 PMC8169418__F1 Effect of COVID-19 on NFKB and Neurological Manifestations of Disease ENSG00000130234 ENSG00000184012 ENSG00000164342 PMC9511411__F5 Inhibitory targeting cGAS-STING-TBK1 axis: Emerging strategies for autoimmune diseases therapy ENSG00000122218 PMC9511411__F4 Inhibitory targeting cGAS-STING-TBK1 axis: Emerging strategies for autoimmune diseases therapy ENSG00000183735 ENSG00000105397 ENSG00000115415 PMC8984481__F1 Escaping Death: How Cancer Cells and Infected Cells Resist Cell-Mediated Cytotoxicity ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000064012 ENSG00000285379 ENSG00000026103 PMC9511411__F7 Inhibitory targeting cGAS-STING-TBK1 axis: Emerging strategies for autoimmune diseases therapy ENSG00000105612 ENSG00000072694 ENSG00000162601 PMC4028619__F1 Linking metabolism and epigenetic regulation in development of hepatocellular carcinoma PMC9669583__F3 8p11 myeloproliferative syndrome: Genotypic and phenotypic classification and targeted therapy ENSG00000115415 ENSG00000150907 ENSG00000168610 PMC3411062__F1 Network pathways analysis of molecules identified in T-cells that are involved in LFA-1/ICAM-1 signaling ENSG00000100526 ENSG00000169032 ENSG00000184916 ENSG00000124762 ENSG00000166508 ENSG00000136603 ENSG00000164056 ENSG00000168214 ENSG00000183337 ENSG00000163235 ENSG00000198742 ENSG00000171621 ENSG00000204217 PMC3075510__F9 Phosphatidylinositol 3-kinase (PI3K)-Akt-glycogen synthase kinase 3 (GSK3) signalling is required for expression of a subset of interleukin-10 (IL-10) inducible genes ENSG00000168610 PMC5449086__F8 Schematic model of the regulatory role of ADAR1 in liver homeostasis ENSG00000108691 ENSG00000088888 PMC8797391__F9 Bioinformatics analysis of BUB1 expression and gene regulation network in lung adenocarcinoma ENSG00000069482 ENSG00000172005 PMC6280705__F1 General eukaryotic translation initiation pathway ENSG00000163435 ENSG00000144895 ENSG00000100664 PMC6527392__F10 Atypical PKCs control actin cytoskeleton via Cofilin activation ENSG00000084112 ENSG00000146648 ENSG00000141298 PMC6892198__F1 Retinoic acid (RA)-signaling pathway ENSG00000095596 ENSG00000135437 ENSG00000187553 ENSG00000184254 ENSG00000138207 ENSG00000003137 ENSG00000121039 ENSG00000196344 ENSG00000128918 PMC10135819__F2 Diagram illustrating RET and RET-regulated NAD+-dependent sirtuin signaling pathway as a contributor and potential therapeutic target for aging, age-related diseases, and ischemic stroke ENSG00000213619 PMC8201404__F2 GIMAP Family Proteins: An Incomplete Puzzle ENSG00000291603 ENSG00000213658 ENSG00000198793 ENSG00000105639 PMC7866155__F1 Targeted Neoadjuvant Therapies in HR+/HER2−Breast Cancers: Challenges for Improving pCR ENSG00000135446 ENSG00000156574 ENSG00000105810 ENSG00000171791 PMC7438278__F7 Working model for induction of cardiomyocyte necroptosis by Cops8 deficiency ENSG00000137275 ENSG00000171791 ENSG00000168404 ENSG00000064012 ENSG00000285379 PMC6121276__F2 Catabolic and pro-inflammatory signaling in osteoarthritis ENSG00000139219 ENSG00000170365 ENSG00000087245 ENSG00000157766 ENSG00000125538 ENSG00000100985 ENSG00000077782 PMC11953998__F22 Design strategies for nanodrugs targeting the mitochondria and lysosomes ENSG00000226492 ENSG00000214285 ENSG00000078098 PMC3977945__F3 Ubiquitination-mediated regulation of the core Wnt/Beta-catenin pathway components ENSG00000135655 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198742 ENSG00000092148 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000083799 ENSG00000235631 ENSG00000101557 PMC3977945__F2 Simplified phosphorylation-mediated regulation of the core Wnt/Beta-catenin pathway components ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000064393 ENSG00000168036 ENSG00000154310 PMC3977945__F1 Simplified Wnt/Beta-catenin pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5381727__F2 Roles of Caspases in Necrotic Cell Death ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000189403 ENSG00000091106 PMC7264424__F8 Calcium signaling pathway ENSG00000130528 ENSG00000156026 ENSG00000186716 ENSG00000148175 PMC8297384__F1 Regulatory T Cells in Epicutaneous Immunotherapy for Food Allergy ENSG00000177575 ENSG00000081041 ENSG00000089692 ENSG00000163739 ENSG00000117335 PMC5826825__F2 Oxygen-responsive transcriptional regulation of lipid homeostasis in fungi: Implications for anti-fungal drug development ENSG00000134755 ENSG00000167653 PMC8074600__F2 Dysregulation of Multiple Signaling Neurodevelopmental Pathways during Embryogenesis: A Possible Cause of Autism Spectrum Disorder ENSG00000106571 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC8074600__F1 Dysregulation of Multiple Signaling Neurodevelopmental Pathways during Embryogenesis: A Possible Cause of Autism Spectrum Disorder ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000150394 PMC3589553__F3 Regulatory mechanisms for the Hippo pathway ENSG00000129474 ENSG00000126016 ENSG00000142192 ENSG00000163914 ENSG00000132849 ENSG00000131023 ENSG00000072415 PMC8339349__F7 lncRNA H19 facilitates the proliferation and differentiation of human dental pulp stem cells via EZH2-dependent LATS1 methylation ENSG00000131023 PMC6134813__F4 Pathways Involved in Ovarian Epithelial Cancer ENSG00000127928 ENSG00000169248 ENSG00000277909 ENSG00000050628 ENSG00000291946 ENSG00000143228 ENSG00000262634 ENSG00000138778 ENSG00000169245 ENSG00000065328 ENSG00000138755 ENSG00000101327 ENSG00000134690 PMC11953998__F24 Synthesis process for the polymer DBD and the formation of NP-DBD nanoparticles ENSG00000183735 ENSG00000164430 PMC3418849__F10 TrkA signaling pathway ENSG00000002330 ENSG00000291971 ENSG00000150907 ENSG00000198793 ENSG00000065559 ENSG00000169032 PMC4209203__F10 Contrasting roles for histone 3 lysine 27 demethylases in acute lymphoblastic leukemia ENSG00000283780 ENSG00000148400 ENSG00000074266 ENSG00000178691 ENSG00000008083 ENSG00000109670 PMC4859987__F1 Terpenoid indole alkaloid pathway ENSG00000197429 ENSG00000241644 PMC2989631__F1 DNA damage response (DDR) pathway ENSG00000149311 ENSG00000012048 ENSG00000163961 ENSG00000112130 PMC11055915__F4 Mitochondrial quality control regulates cell death induced by copper and iron ENSG00000278718 ENSG00000162711 ENSG00000137275 ENSG00000102871 ENSG00000182511 ENSG00000116688 ENSG00000167468 ENSG00000111684 ENSG00000137714 ENSG00000168404 ENSG00000285379 ENSG00000171109 ENSG00000026103 PMC8632002__F2 Why Females Do Better: The X Chromosomal TLR7 Gene-Dose Effect in COVID-19 ENSG00000120280 ENSG00000139370 ENSG00000172936 ENSG00000276561 PMC11187369__F4 Druggable toll-like receptor (TLR) cascades ENSG00000102189 ENSG00000239732 ENSG00000172936 ENSG00000150455 ENSG00000010671 PMC4376477__F1 Neuronal aggregates: formation, clearance and spreading ENSG00000284774 PMC7177938__F4 Gene-Ontology (GO) term enrichment and pathway term network analysis of DEGs shared by ADJ versus PRE and ATT versus PRE lists (1928 DEPs) ENSG00000163914 ENSG00000115718 ENSG00000177084 PMC7865703__F2 STAT3 pathway activation represents a focal point of tumorigenesis and immune escape ENSG00000108691 ENSG00000171791 ENSG00000049768 ENSG00000146648 PMC10216286__F1 The TRAIL apoptosis pathway ENSG00000168040 PMC7381302__F1 Extrinsic apoptosis execution ENSG00000039537 ENSG00000113600 ENSG00000002330 ENSG00000171791 ENSG00000168040 PMC4618842__F1 Pathogenesis of Muscle Wasting in Cancer Cachexia: Targeted Anabolic and Anti-Catabolic Therapies ENSG00000198793 PMC10216286__F2 TRAIL resistance ENSG00000168040 PMC5615369__F1 Novel aspects of tumor biology and translational approaches using zebrafish models ENSG00000288335 ENSG00000107485 ENSG00000175097 PMC7191626__F1 Enzymatic cascade involving the renin-angiotensin system, key receptor systems, and biological effects ENSG00000130234 PMC6997470__F2 PAMPs exposure regulation in response to environmental signals ENSG00000239732 ENSG00000167207 ENSG00000130234 ENSG00000125538 PMC3329953__F8 mTOR pathway in aging ENSG00000198793 ENSG00000167658 ENSG00000167965 PMC11554632__F1 Outline of force-sensing proteins in cardiovascular system ENSG00000135446 ENSG00000198793 ENSG00000103335 PMC9013808__F3 cAMP-Dependent Synaptic Plasticity at the Hippocampal Mossy Fiber Terminal PMC6770909__F1 Redifferentiation of thyroid cancer ENSG00000125482 ENSG00000157764 ENSG00000198793 ENSG00000101464 ENSG00000165409 PMC3218743__F2 Inflammation in the gouty joint ENSG00000175054 ENSG00000162711 ENSG00000172936 PMC6780401__F3 Impacts of mutations in the TGFB signaling transduction components contribute to PDAC development ENSG00000170365 ENSG00000148926 ENSG00000015285 ENSG00000204217 ENSG00000155090 PMC4266469__F1 Schematic demonstrating the effects of AMPK signaling in stroke ENSG00000180210 ENSG00000002330 PMC6447777__F2 Candidates of miRNA-based therapy against perinatal hypoxic-ischemic brain injury ENSG00000178860 ENSG00000084093 ENSG00000168229 ENSG00000136869 PMC7501671__F8 EMfC action in amelioration of inflammatory response and autophagy pathway during anti-hepatic steatosis in HFD-induced obesity mice ENSG00000128272 ENSG00000144895 ENSG00000198793 ENSG00000145782 ENSG00000026103 PMC8498116__F1 Targeting the Integrated Stress Response in Cancer Therapy ENSG00000128272 ENSG00000144895 PMC2635018__F1 Amino acid transporters and nutrient sensing mechanisms ENSG00000169047 ENSG00000133124 PMC8221367__F1 Canonical Wnt Signaling Pathway and Tcf1 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000168646 PMC6050436__F5 MapMan overview of general metabolism for the metabolites and proteins/transcripts of Quercus ilex ENSG00000159224 ENSG00000122966 ENSG00000162600 PMC2805685__F11 Reconstruct part of KEGG pathway by our method ENSG00000100811 ENSG00000159216 ENSG00000112242 ENSG00000115415 ENSG00000139133 ENSG00000171791 ENSG00000146648 PMC4829595__F3 Representation of the cross talk among different pathways under water-deficit conditions ENSG00000204020 ENSG00000163788 PMC6520274__F1 Hydrogen sulfide intervention in cystathionine-Beta-synthase mutant mouse helps restore ocular homeostasis ENSG00000062485 ENSG00000116984 PMC6616371__F3 Identification of Transcripts Potentially Involved in Neural Tube Closure Using RNA-sequencing ENSG00000138795 ENSG00000169071 ENSG00000070831 ENSG00000134982 ENSG00000163914 PMC6813538__F8 Action of EC-7072 targeting the BCR signaling pathway in CLL cells ENSG00000177455 ENSG00000105369 ENSG00000197943 ENSG00000171791 ENSG00000010671 PMC1785270__F6 A model illustrating the positive and negative regulation of PanK2 activity ENSG00000152782 ENSG00000157184 ENSG00000120137 ENSG00000130810 PMC7090043__F2 Context is everything: extrinsic signalling and gain-of-function p53 mutants ENSG00000094631 ENSG00000284774 PMC6616371__F4 Identification of Transcripts Potentially Involved in Neural Tube Closure Using RNA-sequencing PMC5108756__F2 Inhibition of the complement system by pathogenic fungi ENSG00000122194 PMC8401727__F5 Physcomitrium patens Infection by Colletotrichum gloeosporioides: Understanding the Fungal–Bryophyte Interaction by Microscopy, Phenomics and RNA Sequencing ENSG00000157554 PMC7947196__F1 Microglial metabolic programming and immune functions in AD ENSG00000125538 ENSG00000198793 PMC1351030__F8 Krüppel-like factor 5 mediates the transforming activity of oncogenic H-Ras PMC11082748__F4 Graphical representation of the CREB signaling pathway downregulated in the control group (see Figure 3A) ENSG00000137947 ENSG00000005339 ENSG00000152495 ENSG00000188130 ENSG00000281877 ENSG00000160691 PMC3928130__F2 AMP-activated protein kinase (AMPK) beyond metabolism ENSG00000188486 ENSG00000149311 ENSG00000123374 PMC3928130__F4 AMP-activated protein kinase (AMPK) beyond metabolism ENSG00000149311 ENSG00000285069 PMC11082748__F5 Genes (N = 21) detected by IPA as involved in the neuroimmune pathway were entered into a representation using the GeneMANIA algorithm ENSG00000182578 ENSG00000243414 ENSG00000168329 ENSG00000011600 ENSG00000119535 ENSG00000027697 ENSG00000273686 ENSG00000164104 ENSG00000171051 ENSG00000103490 ENSG00000163131 ENSG00000189403 ENSG00000172936 PMC4019832__F2 Activation, signalling and targeting of ErbB receptor family members ENSG00000198793 ENSG00000177606 ENSG00000136997 PMC7504480__F1 eATP/P2X7R Axis: An Orchestrated Pathway Triggering Inflammasome Activation in Muscle Diseases ENSG00000162711 ENSG00000125538 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC3334466__F1 Duo/Cdc42 pathways ENSG00000106683 ENSG00000070831 ENSG00000149269 PMC4287105__F3 Example of difference between LW and MS at fetal gestational age 110: pathway of Gluconeogenesis ENSG00000262785 ENSG00000143158 ENSG00000074800 ENSG00000067057 ENSG00000173599 ENSG00000164708 ENSG00000136872 ENSG00000091140 ENSG00000159399 PMC3928130__F1 AMP-activated protein kinase (AMPK) beyond metabolism ENSG00000230797 PMC8500332__F8 n-butyrate alters the RAP1 signaling pathway in the endometriotic epithelial cells ENSG00000113456 ENSG00000213658 ENSG00000084774 PMC8743870__F8 Triaging Down the 2021 Chest Pain Guidelines ENSG00000084774 PMC11811495__F3 Example of network visualization from the KEGG Pathway database for the “Wnt signalling pathway” (https://www.kegg.jp/pathway/hsa04310), analysed using Orthoweb ENSG00000163904 ENSG00000171444 ENSG00000115266 PMC5527809__F2 Interaction network and subcellular localization of differentially regulated genes by dasatinib in K562 cells ENSG00000160888 ENSG00000120833 ENSG00000185022 ENSG00000123411 ENSG00000114737 ENSG00000136997 ENSG00000138411 ENSG00000139289 ENSG00000178104 ENSG00000152804 ENSG00000100219 ENSG00000162772 PMC6463957__F5 Hub genes and module analysis of the PPI networks ENSG00000184254 ENSG00000108242 ENSG00000149380 ENSG00000184956 ENSG00000113140 ENSG00000134871 ENSG00000137801 ENSG00000291363 ENSG00000196344 ENSG00000292234 ENSG00000291748 ENSG00000072110 ENSG00000108821 ENSG00000198488 ENSG00000196620 ENSG00000187210 PMC8992553__F2 Improving TRAIL-induced apoptosis in cancers by interfering with histone modifications ENSG00000168040 PMC7418797__F1 Therapeutic mechanism related to natural products ENSG00000134982 ENSG00000168036 PMC4276934__F2 Reactome mapping of differentially-expressed genes ENSG00000070778 ENSG00000213928 ENSG00000125148 ENSG00000140968 ENSG00000027697 ENSG00000216490 ENSG00000125347 ENSG00000276561 ENSG00000067066 ENSG00000111537 ENSG00000137265 ENSG00000168310 ENSG00000140464 PMC4410070__F1 Accelerated Vascular Disease in Systemic Lupus Erythematosus: Role of Macrophage ENSG00000162692 PMC7770493__F3 cAMP signalosomes at the endoplasmic reticulum, nucleus, and centrosome ENSG00000065989 ENSG00000105127 ENSG00000113448 PMC7770493__F2 Mitochondrial cAMP signalosomes ENSG00000118508 ENSG00000128654 ENSG00000002330 ENSG00000065989 ENSG00000291971 ENSG00000106554 PMC7770493__F1 Plasma membrane and primary cilium cAMP signalosomes ENSG00000143147 ENSG00000148798 ENSG00000109062 ENSG00000001626 ENSG00000078674 PMC8379492__F9 Hypoglycemic and hypolipidemic effects of blueberry anthocyanins by AMPK activation: In vitro and in vivo studies ENSG00000042832 ENSG00000150907 ENSG00000113161 PMC9179518__F1 Reactive Oxygen Species in Regulating Lymphangiogenesis and Lymphatic Function ENSG00000135218 ENSG00000086991 ENSG00000150630 PMC8021790__F2 Regulatory network model for alanine, aspartic acid and glutamate metabolism pathway(enzyme, posttranslational modification, activate, inhibition, catalysis, reaction, and combine ENSG00000291971 ENSG00000115904 ENSG00000088256 ENSG00000070669 ENSG00000136237 ENSG00000180210 ENSG00000188089 ENSG00000095464 ENSG00000220205 ENSG00000196352 ENSG00000124181 ENSG00000124102 ENSG00000165059 ENSG00000182621 ENSG00000132639 ENSG00000087460 ENSG00000160691 ENSG00000133216 ENSG00000065135 ENSG00000196961 ENSG00000128272 ENSG00000150672 ENSG00000170310 ENSG00000185532 ENSG00000113448 ENSG00000069966 PMC7198709__F1 Biosynthetic pathways of NAD+ in mammalian cells includes de novo, Preiss–Handler, and salvage pathways, and the salvage pathway is the main source of NAD+ ENSG00000105835 ENSG00000123572 ENSG00000278488 PMC8815517__F1 mTOR Signaling in Kidney Diseases ENSG00000155792 ENSG00000167965 PMC4156761__F8 Schematic model shows the downstream signaling pathway of PIP5K1A and the effect of ISA-2011B inhibition ENSG00000145604 ENSG00000143398 PMC4065255__F1 Core components of the insulin-like signaling pathway in C ENSG00000118515 PMC11525629__F3 MAOs in the suppression of antitumor immunity ENSG00000113520 ENSG00000164690 PMC5866357__F3 General overview of metabolic pathways in healthy ECs ENSG00000180210 ENSG00000140263 ENSG00000169710 ENSG00000115419 ENSG00000026103 PMC4038158__F3 Signaling pathway initiated by Edn1-induced Ednra signaling ENSG00000120063 ENSG00000113196 ENSG00000142627 ENSG00000006377 ENSG00000133937 ENSG00000149782 ENSG00000164107 ENSG00000088256 ENSG00000180875 ENSG00000151617 ENSG00000081189 ENSG00000101333 PMC11525629__F1 Signaling pathways activated by mito-DAMPs ENSG00000162711 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000163568 ENSG00000172936 ENSG00000276561 PMC6923371__F3 Schematic illustration of a causal network in the Ingenuity Pathway Analysis (IPA) environment ENSG00000019991 ENSG00000137673 ENSG00000112715 PMC9477818__F1 Antimicrobial potential of a ponericin-like peptide isolated from Bombyx mori L. hemolymph in response to Pseudomonas aeruginosa infection ENSG00000168040 PMC6468149__F1 The Hippo signaling pathway-YAP/TAZ in human endothelial cells ENSG00000167601 ENSG00000126016 ENSG00000109321 ENSG00000114978 ENSG00000114019 ENSG00000131023 ENSG00000291442 ENSG00000137801 PMC8987999__F2 Emerging diabetes therapies: Bringing back the Beta-cells ENSG00000169047 ENSG00000140443 PMC8165279__F1 Dimming the Powerhouse: Mitochondrial Dysfunction in the Liver and Skeletal Muscle of Intrauterine Growth Restricted Fetuses ENSG00000125166 ENSG00000185633 ENSG00000143158 ENSG00000067992 ENSG00000005882 ENSG00000173599 ENSG00000105953 ENSG00000146701 ENSG00000101365 ENSG00000060762 ENSG00000062485 PMC3995556__F9 BTC-stimulated IL-8 production and bio-behaviors of lung cancer cells ENSG00000198793 ENSG00000146648 PMC12103044__F4 Triggers and pathogenesis for pathological scar formation ENSG00000172936 ENSG00000157625 ENSG00000083799 ENSG00000184216 PMC5288206__F6 Treatment with an SLC12A1 antagonist inhibits tumorigenesis in a subset of hepatocellular carcinomas ENSG00000060237 ENSG00000074803 PMC6787567__F3 Involvement and regulation of lncRNAs in M1‐like macrophage polarization ENSG00000150782 ENSG00000164399 ENSG00000113520 ENSG00000172936 ENSG00000136869 ENSG00000096717 ENSG00000175104 ENSG00000104432 ENSG00000197451 ENSG00000113525 PMC6787567__F2 Involvement of lncRNAs in monocyte/macrophage development and M1/M2 switch ENSG00000111537 ENSG00000135503 PMC9207355__F7 CEMIP promotes extracellular matrix‐detached prostate cancer cell survival by inhibiting ferroptosis ENSG00000151012 ENSG00000103888 ENSG00000079999 PMC6923546__F5 Schematic representation of the proposed model: blocking PRMT5 promotes lung cancer cell death via Akt/GSK3B signaling pathway induced by resveratrol PMC3380376__F3 Relationship between binding of ligands to the pattern recognition AGE receptor (RAGE) and inflammation, gene expression, oxidative and nitrosative stress, and damage to the macro- and microvasculature ENSG00000198576 ENSG00000189403 PMC6533683__F1 mTOR signaling pathway regulated autophagy and EMT ENSG00000198793 ENSG00000168036 ENSG00000057663 PMC10511167__F7 MiR-143/145 cluster induced by TGFB1 suppresses Wilms’ tumor 1 expression in cultured human podocytes PMC6533683__F3 P53 signaling pathway regulated autophagy and EMT ENSG00000177169 ENSG00000152348 ENSG00000169554 ENSG00000198793 PMC6533683__F2 Beclin-1 signaling pathway regulated autophagy and EMT ENSG00000125084 PMC6533683__F5 Integrin signaling pathway regulated autophagy and EMT ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC6533683__F6 WNTs signaling pathway regulated autophagy and EMT ENSG00000122691 ENSG00000168036 PMC6533683__F8 TGFB signaling pathway regulated autophagy and EMT ENSG00000065989 ENSG00000168036 ENSG00000168610 ENSG00000057663 PMC7290055__F4 Co-ordinately up-regulated genes of NF-Kappa B signalling pathway in HIV-H ENSG00000095585 ENSG00000149311 ENSG00000100290 ENSG00000226275 ENSG00000213658 ENSG00000135960 ENSG00000102871 ENSG00000083799 ENSG00000150455 PMC6858495__F3 pRB/E2F pathway dysregulation leading to unrestricted CASP3 gene transcription ENSG00000135446 ENSG00000105810 ENSG00000164305 PMC6769035__F1 Tumor microenvironment shapes NK cell metabolism and effector functions ENSG00000198793 PMC6858495__F7 Activation of PC-3 by PAC-1 and its derivatives via chelation of labile inhibitory zinc ENSG00000157764 PMC5927694__F1 A conserved parallel pathway for telomere protection ENSG00000149311 ENSG00000175054 ENSG00000164053 PMC7439780__F6 Protein-protein interaction (PPI) regulatory network of proteins involved in the pentose phosphate pathway (PPP) ENSG00000197713 ENSG00000023697 PMC8036323__F5 Cooperation of autophagy with phagocytosis in microglial activation ENSG00000177169 ENSG00000135218 ENSG00000057663 PMC3089810__F2 Receptors, subcellular compartments and the regulation of peripheral B cell responses: the illuminating state of anergy ENSG00000100290 ENSG00000291971 ENSG00000010671 PMC9011276__F2 Narrative review of the role of the Notch signaling pathway in rheumatoid arthritis ENSG00000128917 ENSG00000148400 ENSG00000074181 ENSG00000090932 PMC6389150__F5 Model of NDV V protein regulating apoptosis in DF-1 cells ENSG00000171791 PMC9334657__F2 Connecting Metabolic Rewiring With Phenotype Switching in Melanoma ENSG00000135218 ENSG00000099194 ENSG00000123983 ENSG00000026103 PMC5347713__F7 Babao Dan attenuates hepatic fibrosis by inhibiting hepatic stellate cells activation and proliferation via TLR4 signaling pathway ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC11206024__F3 TLR4 signaling pathway ENSG00000183735 ENSG00000172936 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC8781800__F3 Current Aspects on the Pathophysiology of Bone Metabolic Defects during Progression of Scoliosis in Neurofibromatosis Type 1 ENSG00000196712 PMC12014465__F2 TGFB1 signaling pathway plays multiple roles in amelogenesis ENSG00000125363 ENSG00000132464 ENSG00000167749 ENSG00000137674 PMC7050993__F5 Helicobacter pylori Deregulates T and B Cell Signaling to Trigger Immune Evasion ENSG00000198793 ENSG00000049768 ENSG00000106100 ENSG00000115009 PMC8781800__F2 Current Aspects on the Pathophysiology of Bone Metabolic Defects during Progression of Scoliosis in Neurofibromatosis Type 1 ENSG00000198793 ENSG00000196712 PMC12014465__F1 TGFB classical signaling pathway ENSG00000164483 PMC4931992__F7 Model of regulatory loop between Shh, IRS1, YAP, and YB1 ENSG00000169047 ENSG00000164690 PMC8227424__F1 4-1BBL as a Mediator of Cross-Talk between Innate, Adaptive, and Regulatory Immunity against Cancer ENSG00000162924 PMC8677621__F8 Possible mechanism by which MCPIP1 regulates the EMT process and the Beta-catenin level ENSG00000124216 ENSG00000019549 ENSG00000183762 ENSG00000183579 ENSG00000168036 ENSG00000106483 ENSG00000168772 PMC7539814__F6 Schematic diagram for blockade of autophagy in stable MED12-mut UtSM clone ENSG00000198793 ENSG00000184634 PMC7019488__F4 Steamed bread and baked bread on the cytokine network (a) and central metabolic pathway metabolic network (b) ENSG00000188379 ENSG00000138798 PMC8606765__F1 T-cell intrinsic Toll-like receptor signaling: implications for cancer immunotherapy and CAR T-cells ENSG00000111537 ENSG00000134982 ENSG00000049768 PMC9213282__F1 Influence of endophytes on rice fitness under environmental stresses ENSG00000105722 ENSG00000100485 PMC8606765__F3 T-cell intrinsic Toll-like receptor signaling: implications for cancer immunotherapy and CAR T-cells ENSG00000177455 ENSG00000104894 ENSG00000172936 PMC8606765__F2 T-cell intrinsic Toll-like receptor signaling: implications for cancer immunotherapy and CAR T-cells ENSG00000174123 ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC6320226__F1 Schematic diagram summarizing the regulatory role of the Id1/IGF2/VEGF/VEGFR pathway in esophageal squamous cell carcinoma (ESCC) progression ENSG00000125968 PMC5086583__F1 Immune effector cells induce tumor cell death through apoptosis and necrotic-like cell lysis ENSG00000137275 ENSG00000168040 ENSG00000168404 ENSG00000285379 ENSG00000026103 PMC6348814__F2 ALDH1A1 regulation, potential retinoid signaling pathways, and functional effects of ALDH in CSCs ENSG00000128917 ENSG00000168036 ENSG00000283100 PMC12115913__F4 The molecular mechanisms involving the interaction between the SARS-CoV-2 S protein and NRP1, DPP4, and CD147 cellular receptors ENSG00000197635 ENSG00000130234 ENSG00000100985 PMC12115913__F2 The molecular mechanisms triggered by the interplay between SARS-CoV-2 S protein, ACE2, and integrin B1 receptors ENSG00000130234 ENSG00000125538 PMC6628717__F3 ErbB-2 Downstream Targets to Promote PCa Tumorigenicity PMC12115913__F1 SARS-CoV-2 infection pathways, spike protein domains, and main receptors ENSG00000167601 ENSG00000140564 ENSG00000130234 ENSG00000184012 ENSG00000136869 PMC6686160__F8 Diagrammatic sketch of the working hypothesis PMC7589635__F1 Genetic pathomechanisms of FSHD types 1 and 2 ENSG00000101596 ENSG00000088305 PMC9111035__F4 Critical evaluation of risk to reward ratio of quercetin supplementation for COVID‐19 and associated comorbid conditions ENSG00000042832 PMC8722265__F8 SNHG15 is a negative regulator of inflammation by mediating TRAF2 ubiquitination in stroke-induced immunosuppression ENSG00000113520 ENSG00000136869 ENSG00000118520 ENSG00000127191 PMC8719534__F5 Human Metabolites of Hamaforton™ (Hamamelis virginiana L. Extract) Modulates Fibroblast Extracellular Matrix Components in Response to UV-A Irradiation ENSG00000087245 ENSG00000259207 ENSG00000113140 ENSG00000149294 ENSG00000101680 ENSG00000137801 ENSG00000053747 ENSG00000213949 ENSG00000041982 ENSG00000118785 ENSG00000157227 ENSG00000026508 ENSG00000100985 PMC3269678__F2 Signaling pathways leading to transcription factors activation in response to UV-radiation ENSG00000144895 ENSG00000178573 ENSG00000173039 ENSG00000079999 PMC7260202__F5 Crosstalk between androgen and Wnt/Beta-catenin leads to changes of wool density in FGF5-knockout sheep ENSG00000138795 ENSG00000168036 ENSG00000164690 PMC5510573__F2 Overview of the human androgen biosynthesis pathways PMC3366852__F5 Proposed mechanistic link between Por deletion and up-regulation of MHC II expression in enterocytes ENSG00000160752 ENSG00000019582 ENSG00000067064 ENSG00000110921 ENSG00000112972 ENSG00000115415 ENSG00000113161 ENSG00000104549 ENSG00000167508 PMC11292615__F0 This review seeks to offer a comprehensive look at how salidroside impacts gut microbiota and its potential therapeutic role in treating atherosclerosis ENSG00000162711 ENSG00000198793 ENSG00000172936 ENSG00000136869 PMC3556575__F5 Pathways of relationships identified by feeding gene expression patterns identified in erythroid progenitors to the Ingenuity software ENSG00000185215 ENSG00000080819 ENSG00000188690 ENSG00000112715 ENSG00000146278 ENSG00000166508 ENSG00000151702 ENSG00000136541 ENSG00000100473 ENSG00000082512 ENSG00000115942 ENSG00000167670 ENSG00000160179 ENSG00000138119 ENSG00000179348 ENSG00000030419 ENSG00000063854 ENSG00000125384 ENSG00000136478 ENSG00000064393 ENSG00000018408 ENSG00000127334 ENSG00000136603 ENSG00000117724 ENSG00000094804 ENSG00000133048 ENSG00000196418 ENSG00000163625 ENSG00000170962 ENSG00000114126 ENSG00000198176 ENSG00000280610 ENSG00000152804 ENSG00000099804 ENSG00000067955 ENSG00000080839 PMC8076952__F8 Blockade of TRPM7 Alleviates Chondrocyte Apoptosis and Articular Cartilage Damage in the Adjuvant Arthritis Rat Model Through Regulation of the Indian Hedgehog Signaling Pathway ENSG00000092439 ENSG00000106571 ENSG00000128602 PMC11529329__F3 RPs and proliferation of HCC ENSG00000161016 ENSG00000134419 ENSG00000109475 ENSG00000135446 PMC11529329__F2 RPs interacting with p53 and MDM2 ENSG00000125691 ENSG00000161970 ENSG00000136869 ENSG00000177600 ENSG00000108107 PMC3223033__F6 Schematic illustration of the main metabolic pathways based on the proteins identified in the citrus pulp chromoplasts ENSG00000180210 ENSG00000126218 ENSG00000101981 PMC11529329__F4 RPs and metastasis of HCC ENSG00000125691 ENSG00000134419 ENSG00000105193 ENSG00000137818 ENSG00000156427 ENSG00000162607 ENSG00000168036 ENSG00000100985 PMC8401288__F1 Single LC-MS/MS Analysis to Quantify CoA Biosynthetic Intermediates and Short-Chain Acyl CoAs ENSG00000138621 ENSG00000068120 ENSG00000127125 PMC6759579__F5 Functional overview of the embryonic complement system ENSG00000288512 ENSG00000203710 ENSG00000196352 ENSG00000117335 ENSG00000120885 ENSG00000166278 ENSG00000117322 ENSG00000182326 ENSG00000236625 ENSG00000108561 PMC9405713__F9 HPV16E7 Affibody as a Novel Potential Therapeutic Agent for Treating Cervical Cancer Is Likely Internalized through Dynamin and Caveolin-1 Dependent Endocytosis ENSG00000135446 PMC3336771__F1 Endogenous polyamines potentiate macrophage polarization ENSG00000136869 ENSG00000118520 PMC10670368__F2 SHP2 is critical in regulating RAS/ERK, PI3K/Akt, and JAK/STAT signaling pathways in cancer cells ENSG00000291971 ENSG00000198793 PMC7139883__F12 Sphingosine kinase 1/S1P signaling contributes to pulmonary fibrosis by activating Hippo/YAP pathway and mtROS ENSG00000183018 PMC9356176__F12 The cystathionine Beta-synthase / H2S pathway in the development of cellular metabolic dysfunction and pseudohypoxia in down syndrome ENSG00000131473 ENSG00000146733 ENSG00000062485 ENSG00000026103 PMC4748291__F5 Paediatric obstructive sleep apnoea syndrome (OSAS) is associated with tonsil colonisation by Streptococcus pyogenes ENSG00000172936 ENSG00000136869 PMC5569910__F1 The aryl hydrocarbon receptor (AHR) signaling pathway (A) is best known for the induction of xenobiotic metabolizing genes via activation by environmental toxicants ENSG00000110711 ENSG00000106546 PMC6343613__F1 Mechanism of IL-22, IL-22receptor as well as IL-22BP and signaling pathway ENSG00000105397 ENSG00000115415 ENSG00000168610 PMC3222852__F1 GSK3 plays pivotal roles in the establishment and maintenance of neuronal polarization ENSG00000197892 ENSG00000134982 ENSG00000198793 PMC434255__F13 Current model for IL-7R regulation of survival and proliferation ENSG00000171791 ENSG00000105639 ENSG00000104432 PMC5575761__F2 Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway ENSG00000213658 ENSG00000156127 ENSG00000198793 ENSG00000154016 PMC3222852__F2 GSK3 is a key regulator of axon growth and branching ENSG00000134982 ENSG00000077279 ENSG00000145321 PMC2676714__F4 Pathways analysis on the set of genes contained in the SNP component PMC5209629__F8 Inflammatory players implicated in lipopolysaccharide- (LPS-) induced M1 polarization of N9 microglial cells and of exosome upregulated microRNAs ENSG00000162711 ENSG00000168329 ENSG00000125538 ENSG00000189403 ENSG00000136869 ENSG00000118520 PMC8125037__F2 PI3K/mTOR Pathway Is Targeted by Rare Germline Variants in Patients with Both Melanoma and Renal Cell Carcinoma ENSG00000170322 ENSG00000163930 ENSG00000163939 ENSG00000198793 ENSG00000181555 ENSG00000168610 ENSG00000087460 ENSG00000128908 PMC5454924__F1 Schematic presentation of ROS scavenging pathway in chloroplasts ENSG00000173599 ENSG00000105227 PMC6200938__F6 Rag-independent Gln stimulation of mTORC1 via PLD-derived PA ENSG00000168003 ENSG00000143761 ENSG00000006451 ENSG00000173599 ENSG00000103257 PMC5292650__F1 Human myeloid cells identified in the bone marrow, blood, and tissue of cancer patients ENSG00000177575 ENSG00000170458 ENSG00000129226 PMC3087899__F6 NFKB pathway activation via death receptor signaling ENSG00000102871 ENSG00000056558 ENSG00000168040 ENSG00000127191 PMC11892029__F3 RNA methylation, DNA methylation, and demethylation in PH ENSG00000088305 ENSG00000198492 ENSG00000179222 ENSG00000127528 ENSG00000091542 ENSG00000179820 ENSG00000146457 ENSG00000140465 ENSG00000136826 ENSG00000111145 ENSG00000149658 ENSG00000073792 ENSG00000275272 ENSG00000165819 ENSG00000204217 PMC3997115__F1 Caspase activation by the extrinsic (Fas-mediated) apoptosis pathway (left) vs ENSG00000162711 ENSG00000168040 ENSG00000026103 PMC8073493__F2 Non-Coding RNAs in the Neuroprotective Effects of Glutathione ENSG00000124102 PMC11892029__F2 BMPR2 and CAV‐1 in PAH ENSG00000001167 ENSG00000134057 ENSG00000074181 ENSG00000171759 ENSG00000168036 ENSG00000204217 PMC8007978__F2 Metabolism of macrophages is beneficial to host defense or pathogen survival of during Mtb infection ENSG00000180210 ENSG00000118520 ENSG00000159399 PMC2843003__F3 Epicardial-Myocardial Signaling Directing Coronary Vasculogenesis ENSG00000285109 ENSG00000168036 ENSG00000164690 ENSG00000128602 ENSG00000077782 ENSG00000276799 PMC5033243__F2 Emerging role of mTOR in the response to cancer therapeutics ENSG00000167601 ENSG00000157404 ENSG00000171105 ENSG00000065361 ENSG00000134982 ENSG00000145979 ENSG00000146648 ENSG00000196712 PMC6913967__F3 Contribution of ROS and metabolic status to neonatal and adult CD8+ T cell activation ENSG00000213658 ENSG00000026103 PMC11515775__F2 Caffeine metabolism pathway and metabolites ENSG00000140505 ENSG00000255974 ENSG00000118777 ENSG00000127948 ENSG00000106546 PMC4822253__F1 BMP pathway ENSG00000170365 ENSG00000283060 ENSG00000125968 PMC6813227__F6 Signaling pathways ENSG00000140992 ENSG00000198793 ENSG00000108443 ENSG00000141564 ENSG00000096717 ENSG00000187840 ENSG00000140443 ENSG00000283100 PMC5260886__F8 The serglycin–CD44 signaling pathway in NPC ENSG00000136997 ENSG00000026508 ENSG00000168036 PMC5522110__F3 Subset of microRNAs defining the side population of a human malignant mesothelioma cell line ENSG00000169291 ENSG00000002330 ENSG00000110395 ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000158458 ENSG00000169752 PMC7842751__F9 Cocaine-Dependent Acquisition of Locomotor Sensitization and Conditioned Place Preference Requires D1 Dopaminergic Signaling through a Cyclic AMP, NCS-Rapgef2, ERK, and Egr-1/Zif268 Pathway ENSG00000109756 PMC3565104__F4 Proposed model for progesterone and retinoid action in endometrium and endometriosis ENSG00000095596 ENSG00000086696 ENSG00000143320 PMC11515775__F4 Genetic variants and their effects on caffeine dependence ENSG00000009950 ENSG00000140505 ENSG00000255974 ENSG00000173064 ENSG00000118777 ENSG00000127948 ENSG00000149295 ENSG00000106546 PMC3652335__F2 Lin28: Primal Regulator of Growth and Metabolism in Stem Cells ENSG00000071564 ENSG00000131914 ENSG00000083223 ENSG00000136997 ENSG00000187772 ENSG00000134744 PMC307558__F1 TGFB signaling pathway ENSG00000123374 PMC3814821__F8 Proposed mechanism for the CD8+-cell-mediated suppression of HIV-1 replication ENSG00000139193 ENSG00000126353 ENSG00000135828 ENSG00000142166 PMC4259288__F4 A.Genes with altered expression upon miR-224 stimulation are involved in the cell cycle control ENSG00000149311 ENSG00000175054 ENSG00000123374 ENSG00000169375 PMC4090148__F11 Evidence that RASSF1C Stimulation of Lung Cancer Cell Proliferation Depends on IGFBP-5 and PIWIL1 Expression Levels ENSG00000149311 ENSG00000168036 ENSG00000115461 ENSG00000275051 PMC6205166__F4 Leukemia inhibitory factor via the Toll-like receptor 5 signaling pathway involves aggravation of cachexia induced by human gastric cancer-derived 85As2 cells in rats ENSG00000177606 ENSG00000157625 ENSG00000168610 ENSG00000127948 PMC7277968__F7 Reverse cholesterol transport pathway and intravascular remodeling of lipoprotein particles during the postprandial phase ENSG00000042832 PMC6205166__F9 Cachexia-inducing ability of 85As2 cells ENSG00000187554 ENSG00000128342 ENSG00000184216 PMC8955777__F8 Metformin Enhances TKI-Afatinib Cytotoxic Effect, Causing Downregulation of Glycolysis, Epithelial–Mesenchymal Transition, and EGFR-Signaling Pathway Activation in Lung Cancer Cells ENSG00000138798 ENSG00000177606 PMC5709760__F9 TGF‐B1 secreted by Tregs in lymph nodes promotes breast cancer malignancy via up‐regulation of IL‐17RB ENSG00000056736 PMC4133502__F1 Step forward back to (induced) fetal ENSG00000149311 ENSG00000177606 PMC9340150__F2 Structure, biosynthesis, and biological roles of fetuin-A: A review ENSG00000111537 ENSG00000086991 PMC3298733__F1 New therapies targeting the deregulated pathways to treat TICs in pancreatic cancer ENSG00000148400 ENSG00000272398 ENSG00000026508 PMC8952793__F8 Global MicroRNA Expression Profiling of Buffalo (Bubalus bubalis) Embryos at Different Developmental Stages Produced by Somatic Cell Nuclear Transfer and In-Vitro Fertilization Using RNA Sequencing ENSG00000095739 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 PMC4026697__F3 VKR signaling pathways ENSG00000107338 ENSG00000198793 PMC10311107__F7 Metabolic and transcriptomic analyses elucidate a novel insight into the network for biosynthesis of carbohydrate and secondary metabolites in the stems of a medicinal orchid Dendrobium nobile ENSG00000171759 PMC9479684__F4 When does hepatitis B virus meet long-stranded noncoding RNAs? ENSG00000292096 ENSG00000132646 ENSG00000198793 PMC9479684__F3 When does hepatitis B virus meet long-stranded noncoding RNAs? ENSG00000159128 ENSG00000105397 ENSG00000027697 ENSG00000168310 ENSG00000243646 ENSG00000142166 PMC9479684__F6 When does hepatitis B virus meet long-stranded noncoding RNAs? ENSG00000179750 ENSG00000067900 ENSG00000168610 PMC9479684__F5 When does hepatitis B virus meet long-stranded noncoding RNAs? ENSG00000239732 ENSG00000111537 ENSG00000183496 ENSG00000173039 ENSG00000108654 ENSG00000168610 ENSG00000163517 PMC9031068__F2 Plant-Derived Active Constituents in Cancer Treatment and Their Mechanisms of Action ENSG00000291971 ENSG00000168036 PMC9479684__F2 When does hepatitis B virus meet long-stranded noncoding RNAs? ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000167207 ENSG00000172936 ENSG00000135828 ENSG00000164342 PMC12035894__F2 Carcinogenic mechanisms of estrogen and its metabolites in breast cells ENSG00000112715 ENSG00000146648 PMC3976256__F9 Mycobacterium bovis BCG Triggered MyD88 Induces miR-124 Feedback Negatively Regulates Immune Response in Alveolar Epithelial Cells ENSG00000174125 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC4911278__F5 Alternate metabolic programs define regional variation of relevant biological features in renal cell carcinoma progression ENSG00000262785 ENSG00000160883 ENSG00000136872 ENSG00000091140 PMC5352068__F14 PDE5 inhibitors enhance the lethality of pemetrexed through inhibition of multiple chaperone proteins and via the actions of cyclic GMP and nitric oxide ENSG00000149311 ENSG00000177169 ENSG00000144895 ENSG00000198793 ENSG00000168610 PMC9040349__F14 Innovative mouse models for the tumor suppressor activity of Protocadherin-10 isoforms ENSG00000109452 ENSG00000177238 ENSG00000077044 ENSG00000101280 ENSG00000169783 ENSG00000049283 ENSG00000124126 ENSG00000160999 ENSG00000092096 ENSG00000169618 ENSG00000046889 ENSG00000168546 ENSG00000125861 ENSG00000164695 ENSG00000132819 ENSG00000024422 ENSG00000135097 ENSG00000182253 PMC11033467__F5 Immunomodulatory effects of a probiotic combination treatment to improve the survival of Pacific oyster (Crassostrea gigas) larvae against infection by Vibrio coralliilyticus ENSG00000023445 ENSG00000110330 ENSG00000118503 ENSG00000101782 ENSG00000172936 ENSG00000136869 ENSG00000101843 ENSG00000101197 ENSG00000164342 ENSG00000084774 PMC3130144__F6 Molecular mechanism of autophagy with synthesis of cathepsin D ENSG00000239732 ENSG00000198382 ENSG00000126775 ENSG00000164342 PMC3877165__F2 Schematic view of integration of TCR signal transduction with diverse components of the actin polymerization machinery ENSG00000291603 ENSG00000070831 ENSG00000134982 ENSG00000184922 ENSG00000113263 ENSG00000141968 PMC8623138__F1 Microalgae Xanthophylls: From Biosynthesis Pathway and Production Techniques to Encapsulation Development ENSG00000197429 ENSG00000062485 PMC7495093__F7 Pyroptosis of acute kidney injury (AKI) signaling and protective effect of SalB through the nuclear factor erythroid-2 related factor 2 (Nrf2)/NLR family pyrin domain-containing 3 (NLRP3) pathway ENSG00000278718 ENSG00000162711 ENSG00000265972 PMC5482648__F8 High expression of PTBP1 promote invasion of colorectal cancer by alternative splicing of cortactin ENSG00000011304 ENSG00000291971 PMC3957180__F1 Scheme depicting interactions of the ET and NO pathway as described in this chapter ENSG00000007171 PMC9491642__F1 Investigational therapeutics targeting the IL-4/IL-13/STAT-6 pathway for the treatment of asthma ENSG00000105397 ENSG00000131724 ENSG00000105639 ENSG00000106546 PMC8990771__F3 Bax/Bcl-2 Cascade Is Regulated by the EGFR Pathway: Therapeutic Targeting of Non-Small Cell Lung Cancer ENSG00000138798 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC8263655__F3 Long noncoding RNAs on tumor immune escape by regulating immune cells differentiation and function ENSG00000108691 ENSG00000121807 ENSG00000150630 PMC5408751__F7 GSK-3B modulation of LKB1-AMPK pathway in autophagy induction ENSG00000177169 ENSG00000198793 PMC8990771__F2 Bax/Bcl-2 Cascade Is Regulated by the EGFR Pathway: Therapeutic Targeting of Non-Small Cell Lung Cancer ENSG00000163235 ENSG00000138798 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC7021580__F3 MED12 and Cancer Drug Resistance ENSG00000138798 ENSG00000170558 ENSG00000184634 ENSG00000142453 ENSG00000168036 ENSG00000146648 PMC11012648__F3 Informed by Cancer Stem Cells of Solid Tumors: Advances in Treatments Targeting Tumor-Promoting Factors and Pathways ENSG00000134982 ENSG00000102312 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC11012648__F1 Informed by Cancer Stem Cells of Solid Tumors: Advances in Treatments Targeting Tumor-Promoting Factors and Pathways ENSG00000184254 ENSG00000119888 ENSG00000026508 ENSG00000168036 ENSG00000196352 ENSG00000128602 ENSG00000121966 PMC3868999__F1 The Hippo pathway signaling cascade results in the phosphorylation and cytoplasmic retention of effector molecules YAP and TAZ ENSG00000150457 ENSG00000131023 PMC5487850__F1 Biogenesis of microRNA (miRNA), extracellular vesicles (EV) and uptake mechanisms ENSG00000181163 ENSG00000113360 ENSG00000123908 PMC9088184__F6 PGK1-coupled HSP90 stabilizes GSK3B expression to regulate the stemness of breast cancer stem cells ENSG00000168036 PMC7438542__F1 Co-stimulatory signals that enhance MAIT cell activation ENSG00000162594 ENSG00000168610 ENSG00000168685 PMC5380038__F2 DHS and PHS metabolic pathways ENSG00000167769 ENSG00000285281 ENSG00000135587 ENSG00000143418 ENSG00000139624 ENSG00000063176 ENSG00000223802 ENSG00000172292 ENSG00000072210 ENSG00000154227 ENSG00000143753 ENSG00000292130 ENSG00000188611 ENSG00000166224 ENSG00000078124 ENSG00000148154 ENSG00000163082 PMC11993959__F2 Signalling pathways that regulate osteoblastogenesis ENSG00000128602 PMC6022935__F1 Streptomyces lividans major secretory route (Sec pathway) ENSG00000166033 ENSG00000115317 PMC2821476__F3 TNFA induced signaling ENSG00000078747 ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC3241928__F8 Beta-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas ENSG00000127445 ENSG00000065833 ENSG00000157764 ENSG00000168036 PMC5380038__F6 PHS metabolic pathway ENSG00000063176 ENSG00000072210 ENSG00000166224 PMC5380038__F5 Predicted PHS degradation pathway ENSG00000139624 ENSG00000063176 ENSG00000223802 ENSG00000172292 ENSG00000072210 ENSG00000154227 ENSG00000166224 ENSG00000148154 ENSG00000285281 ENSG00000143418 ENSG00000163082 PMC6214130__F2 Trimethylamine N-Oxide: A Link among Diet, Gut Microbiota, Gene Regulation of Liver and Intestine Cholesterol Homeostasis and HDL Function ENSG00000135218 ENSG00000167910 ENSG00000160179 ENSG00000135929 PMC9003256__F8 Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop ENSG00000116688 ENSG00000188158 ENSG00000171109 PMC8234904__F2 Evidence-Based Chemotherapy for Oral Cancer: Focus on Drug Resistance Related to the Epithelial-Mesenchymal Transition PMC9030030__F3 Early T-Cell Precursor ALL and Beyond: Immature and Ambiguous Lineage T-ALL Subsets ENSG00000122025 ENSG00000002330 ENSG00000198793 PMC8228802__F2 ATM: Main Features, Signaling Pathways, and Its Diverse Roles in DNA Damage Response, Tumor Suppression, and Cancer Development ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000172613 ENSG00000123374 ENSG00000198586 PMC8882844__F2 Mitochondrial DNA Depletion Syndrome and Its Associated Cardiac Disease ENSG00000163541 ENSG00000172340 PMC8395197__F8 Smad2/3 Activation Regulates Smad1/5/8 Signaling via a Negative Feedback Loop to Inhibit 3T3-L1 Adipogenesis ENSG00000166819 ENSG00000187288 PMC6061130__F3 Parkinson Disease from Mendelian Forms to Genetic Susceptibility: New Molecular Insights into the Neurodegeneration Process ENSG00000099968 ENSG00000116688 ENSG00000158828 ENSG00000069509 ENSG00000171109 PMC9300530__F3 Metabolomics for the design of new metabolic engineering strategies for improving aerobic succinic acid production in Escherichia coli ENSG00000069482 ENSG00000122966 ENSG00000172005 ENSG00000096088 ENSG00000169184 PMC5146200__F1 Priming and activation of the NLRP3 inflammasome ENSG00000162711 ENSG00000189403 ENSG00000136869 PMC6620619__F4 Platelets involvement in the pathogenesis of AAVs ENSG00000110799 ENSG00000162692 PMC1796761__F1 Pathway of double-stranded break repair by homologous recombination and the factors involved ENSG00000139618 PMC7643020__F3 Crosstalk between autophagy and apoptosis ENSG00000102871 ENSG00000144848 ENSG00000057663 ENSG00000115317 PMC5226613__F1 Signaling involved in autophagy machinery in keratinocytes and therapeutic approaches for skin diseases ENSG00000066468 ENSG00000198793 ENSG00000140285 ENSG00000145782 PMC5226613__F3 Signaling involved in autophagy machinery in keratinocytes and therapeutic approaches for skin diseases ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000146648 PMC11202101__F1 Interleukin-17 signaling pathway (Kyoto Encyclopedia of Genes and Genomes (KEGG) ID: Human (Homo sapiens), hsa04657) ENSG00000144063 ENSG00000142192 ENSG00000081041 ENSG00000102871 ENSG00000105656 ENSG00000169429 ENSG00000168040 ENSG00000143556 ENSG00000115009 PMC7533893__F6 NRF2 in regulation of cancer cell metabolism ENSG00000109814 ENSG00000065833 ENSG00000122966 ENSG00000129596 ENSG00000092621 ENSG00000172005 ENSG00000026103 PMC10536424__F3 Anti-cancer mechanisms of PDE5 inhibitors ENSG00000198793 ENSG00000118520 ENSG00000007171 PMC9248441__F2 Understanding the Potential and Risk of Bacterial Siderophores in Cancer ENSG00000148346 ENSG00000026103 PMC6752947__F6 Tbx1-Isl1-Met genetic pathway regulates only a subset of CPM-derived muscles ENSG00000009709 ENSG00000019991 ENSG00000111049 ENSG00000122180 ENSG00000173599 ENSG00000135678 ENSG00000016082 PMC7533893__F3 Mechanisms involved in the aberrant activation of KEAP1/NRF2 pathway in cancer ENSG00000083093 ENSG00000254986 ENSG00000116044 ENSG00000204520 ENSG00000079999 PMC7533893__F2 Classical KEAP1/NRF2 signaling pathway ENSG00000065833 ENSG00000271303 ENSG00000176153 ENSG00000023909 ENSG00000079999 PMC10380440__F3 Sexual Dimorphism of Skeletal Muscle in a Mouse Model of Breast Cancer: A Functional and Molecular Analysis ENSG00000111537 ENSG00000226492 ENSG00000127022 ENSG00000231925 ENSG00000081051 PMC10380440__F2 Sexual Dimorphism of Skeletal Muscle in a Mouse Model of Breast Cancer: A Functional and Molecular Analysis ENSG00000130528 ENSG00000118729 ENSG00000198626 PMC9180643__F3 Monoubiquitination in Homeostasis and Cancer ENSG00000171720 ENSG00000132646 PMC9651583__F4 Integrated text mining and PPI for the combined effects of Hst and VCR on cancer-related signaling pathways ENSG00000132906 ENSG00000105329 ENSG00000111837 ENSG00000198793 ENSG00000177606 ENSG00000136997 ENSG00000171791 ENSG00000112715 ENSG00000073756 ENSG00000064012 ENSG00000164305 PMC7430831__F6 NOD-like receptor signaling pathway and DEGs in NOD-like receptor signaling pathway from KEGG enrichment analysis of R ENSG00000183735 ENSG00000088888 ENSG00000167207 ENSG00000160703 ENSG00000131323 ENSG00000106100 ENSG00000276561 PMC6879841__F6 Pathway diagram of glycolysis, pentose phosphate pathway (PPP), and tricarboxylic acid (TCA) cycle highlighting metabolites that differed between control (CON) and intrauterine growth restriction (IUGR) fetal skeletal muscle and plasma ENSG00000060982 ENSG00000152556 PMC7698939__F1 Tryptophan metabolism through the kynurenine (yellow), serotonin (blue), and indole (purple) metabolic pathways PMC2718504__F5 Predicted general metabolism and solute transport in T ENSG00000178860 ENSG00000184207 ENSG00000105402 ENSG00000127948 PMC12093341__F1 Biosynthetic pathway of CR and strategies used in this study PMC9113786__F1 Obesity Due to Steroid Receptor Coactivator-1 Deficiency Is Associated With Endocrine and Metabolic Abnormalities ENSG00000115138 ENSG00000168610 PMC9442958__F10 ADSCs stimulated by VEGF-C alleviate intestinal inflammation via dual mechanisms of enhancing lymphatic drainage by a VEGF-C/VEGFR-3-dependent mechanism and inhibiting the NFKB pathway by the secretome ENSG00000150630 PMC4644174__F8 Proposed signaling pathway for TOB-1-mediated progesterone signaling.Notes: TOB-1 was involved in the growth arrest pathway in response to progesterone in MCF-7 cells ENSG00000141232 PMC3561798__F6 Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis ENSG00000197915 ENSG00000163207 ENSG00000106603 ENSG00000006606 ENSG00000105639 ENSG00000196396 ENSG00000143631 ENSG00000106546 PMC6514922__F1 Hypothetical model for the role of thrombomodulin (TM) in mitogen-activated protein kinases (MAPKs) signaling: Thrombomodulin regulates the activation of MAPKs under various pathophysiological conditions ENSG00000134982 ENSG00000173599 ENSG00000170989 ENSG00000077782 PMC4682714__F2 Provides a schematic and abbreviated overview of the TGFB signaling pathway with indication of aneurismal diseases linked to it PMC3875822__F1 Metabolic model of C4 assimilation, rates of reaction, and net fluxes between and ENSG00000172005 ENSG00000198125 PMC4263397__F9 Rgs6 is Required for Adult Maintenance of Dopaminergic Neurons in the Ventral Substantia Nigra ENSG00000070193 ENSG00000107859 PMC8851748__F1 Viral and cellular oncoproteins inhibit the cGAS/STING pathway ENSG00000183735 ENSG00000164430 PMC7040094__F1 C-Type Lectin-Like Receptors: Head or Tail in Cell Death Immunity ENSG00000172322 ENSG00000187796 ENSG00000125538 ENSG00000197992 PMC12003952__F10 PLEVPs deliver pab-miR396a-5p to mediate down-regulation of the IL-17 signaling pathway ENSG00000169245 ENSG00000168610 PMC9535337__F1 Complement activation in Hidradenitis suppurativa: Covert low-grade inflammation or innocent bystander? ENSG00000039537 ENSG00000111537 ENSG00000113600 ENSG00000203710 ENSG00000085265 ENSG00000166278 ENSG00000117322 PMC11843235__F6 Working model for ADAM10 in lung cancer ENSG00000148400 ENSG00000170558 ENSG00000100985 ENSG00000137845 PMC5400641__F8 MiR-519d impedes cisplatin-resistance in breast cancer stem cells by down-regulating the expression of MCL-1 PMC3092676__F4 Emerging molecular functions of RASSF8 ENSG00000291971 ENSG00000168036 PMC3075071__F1 Parsing out the complexity of RAF inhibitor resistance PMC5727283__F5 ER stress and the caspase proteolytic system are important regulators of muscle protein homeostasis ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000145782 ENSG00000057663 PMC6994936__F8 Proposed involvement of FGF9/FGFR2 signalling in human fetal gonad development ENSG00000162552 ENSG00000066468 ENSG00000125398 ENSG00000102678 PMC8502912__F8 LPA1-mediated PKD2 activation promotes LPA-induced tissue factor expression via the p38A and JNK2 MAPK pathways in smooth muscle cells ENSG00000008710 ENSG00000198670 PMC9265296__F1 New Insights into Hippo/YAP Signaling in Fibrotic Diseases ENSG00000197905 ENSG00000131023 PMC10520536__GA1 Neuroepithelial cell-transforming 1 promotes cardiac fibrosis via the Wnt/Beta-catenin signaling pathway ENSG00000134982 ENSG00000168036 ENSG00000108821 PMC6810856__F10 Rhinovirus -induced SIRT-1 via TLR2 regulates subsequent type I and type III interferon responses in airway epithelial cells ENSG00000174125 ENSG00000213928 ENSG00000115415 ENSG00000096717 PMC2915755__F1 PCNA-coupled p21 degradation after DNA damage: the exception that confirms the rule? ENSG00000175054 ENSG00000167986 PMC8194282__F2 Neuroinflammation in Post-traumatic Epilepsy ENSG00000172936 ENSG00000136869 PMC8965109__F9 Prognostic Values and Underlying Regulatory Network of Cohesin Subunits in Esophageal Carcinoma ENSG00000118007 ENSG00000157077 ENSG00000123066 ENSG00000023287 ENSG00000115904 ENSG00000168036 ENSG00000121879 ENSG00000179295 ENSG00000153107 ENSG00000157500 ENSG00000039319 ENSG00000104320 ENSG00000184634 ENSG00000162607 ENSG00000123374 ENSG00000185591 ENSG00000196914 ENSG00000120868 ENSG00000135503 ENSG00000253729 ENSG00000107779 ENSG00000136492 ENSG00000005339 ENSG00000108055 ENSG00000067900 ENSG00000108510 ENSG00000101972 ENSG00000110395 ENSG00000114126 ENSG00000164754 ENSG00000080839 ENSG00000114739 PMC2970576__F5 Analysis of gene expression in CD44+/CD24− MCF-7/ADR cell population by TaqMan Low-Density Array and Ingenuity Pathway analysis ENSG00000100811 ENSG00000104365 ENSG00000284774 ENSG00000117228 ENSG00000291971 ENSG00000221869 ENSG00000106546 ENSG00000245848 ENSG00000077150 ENSG00000143815 ENSG00000135446 ENSG00000104320 ENSG00000177606 ENSG00000136997 ENSG00000100985 ENSG00000253729 ENSG00000026103 ENSG00000141456 PMC4921268__F2 Searching for the Chokehold of NRAS Mutant Melanoma ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC4535548__F12 ERK/MAPK signaling pathway was regulated when THP-1-derived macrophages were treated with the novel NP-siRNA liposomes at 12.5 μg/mL for 24 hours.Notes: The proteomic response was determined by SILAC, and pathways were analyzed using IPA ENSG00000172680 ENSG00000002330 ENSG00000291971 ENSG00000131196 ENSG00000089159 PMC7920285__F1 The differences in the localization of the upstream regulators and the core cascade components of the Hippo signaling pathway during murine and bovine embryogenesis ENSG00000126016 ENSG00000186575 PMC4535548__F11 EIF2 signaling pathway was regulated when THP-1-derived macrophages were treated with the novel NP-siRNA liposomes at 12.5 μg/mL for 24 hours.Notes: The proteomic response was determined by SILAC, and the pathways were analyzed using IPA ENSG00000144895 PMC3549669__F6 STING Specifies IRF3 phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway ENSG00000183735 ENSG00000163565 PMC2572856__F1 Aging of signal transduction pathways, and pathology ENSG00000134982 ENSG00000156574 ENSG00000128602 PMC5354754__F1 Novel non-canonical Wnt signature for prostate cancer aggressiveness ENSG00000010810 ENSG00000177606 PMC4535548__F14 PI3K/AKT and HSP90 interacted with ERK1/2 when THP-1-derived macrophages were treated with the novel NP-siRNA liposomes at 12.5 μg/mL for 24 hours.Notes: The proteomic response was determined by SILAC, and pathways were analyzed using IPA ENSG00000002330 ENSG00000198793 PMC5406709__F1 PI3K pathway targeting agents in development for the treatment of prostate cancer PMC6631185__F4 Signaling pathway nodes effected by loss of CDK11 in A375 melanoma cells following PanCancer Reactome pathways analysis ENSG00000136492 ENSG00000175793 ENSG00000077152 ENSG00000181544 ENSG00000163918 ENSG00000187741 ENSG00000073111 ENSG00000158169 ENSG00000101224 ENSG00000145386 ENSG00000166508 ENSG00000139618 ENSG00000012048 ENSG00000116670 ENSG00000134574 ENSG00000134057 ENSG00000132646 ENSG00000136997 ENSG00000170430 ENSG00000100479 ENSG00000123374 ENSG00000133119 ENSG00000095002 ENSG00000175305 PMC7925099__F1 HIV-1 life cycle, assembly pathway, and assembly plate screen PMC4535548__F13 NFKB signaling pathway was regulated via ERK1/2 when THP-1-derived macrophages were treated with the novel NP-siRNA liposomes at 12.5 μg/mL for 24 hours.Notes: The proteomic response was determined by SILAC, and pathways were analyzed using IPA ENSG00000127191 PMC2844640__F3 Role of Radiation-induced TGF-beta Signaling in Cancer Therapy PMC2904914__F2 Glial cell line-derived neurotrophic factor can signal through a Ras-induced pathway in SSCs ENSG00000123374 ENSG00000123268 PMC3296744__F11 Evolution of JAK-STAT Pathway Components: Mechanisms and Role in Immune System Development ENSG00000105397 ENSG00000033800 PMC2904914__F1 Glial cell line-derived neurotrophic factor can signal through activation of Src kinases in SSCs ENSG00000291971 PMC2844640__F1 Role of Radiation-induced TGF-beta Signaling in Cancer Therapy PMC7917554__F3 Pyroptosis ENSG00000162711 ENSG00000137757 ENSG00000125538 ENSG00000196954 PMC3546685__F1 Short-patch (SP-) and long-patch base excision repair (LP-BER) sub-pathways ENSG00000109674 ENSG00000292286 ENSG00000132646 ENSG00000140398 PMC7917554__F4 Key features of different forms of regulated cell death ENSG00000143799 ENSG00000167468 PMC11015457__F9 Compound-target-pathway network ENSG00000143799 ENSG00000157404 ENSG00000081237 ENSG00000291971 ENSG00000198793 ENSG00000171791 ENSG00000169032 ENSG00000112715 ENSG00000121879 ENSG00000073756 ENSG00000168610 ENSG00000164305 ENSG00000132170 ENSG00000128052 ENSG00000177606 ENSG00000164362 ENSG00000100985 ENSG00000096717 ENSG00000146648 ENSG00000140443 ENSG00000198625 PMC2665757__F6 EXT/HSPG pathway involved in both peripheral and central chondrosarcomas ENSG00000182197 ENSG00000163501 ENSG00000151348 PMC8616344__F7 Identification of Gene Co-Expression Networks Associated with Consensus Molecular Subtype-1 of Colorectal Cancer ENSG00000132906 ENSG00000002330 ENSG00000134982 ENSG00000136997 ENSG00000122008 PMC8569219__F6 Studying the tumor microenvironment and engineering of tumor organoids ENSG00000163930 ENSG00000157764 ENSG00000134982 ENSG00000145321 ENSG00000121879 ENSG00000196712 PMC8474014__F8 Transcriptomic and Metabolomic Analyses Provide Insights Into an Aberrant Tissue of Tea Plant (Camellia sinensis) PMC7699519__F1 The NRF2 pathway ENSG00000174156 ENSG00000151012 ENSG00000265972 ENSG00000176153 ENSG00000023909 ENSG00000079999 ENSG00000065833 ENSG00000178573 ENSG00000100387 ENSG00000113558 ENSG00000284099 ENSG00000106853 ENSG00000168765 ENSG00000156273 PMC12045473__F3 Chloride channel regulation in human diseases ENSG00000165891 ENSG00000169047 ENSG00000198793 ENSG00000079432 ENSG00000001626 PMC10474666__F4 FBXW7 in breast cancer: mechanism of action and therapeutic potential ENSG00000198793 ENSG00000173039 ENSG00000109670 PMC3702632__F7 TLR4 and chemokine receptor crosstalk ENSG00000136869 ENSG00000121807 PMC7195637__F5 Regulation of mTOR on Th17 cell differentiation ENSG00000162676 ENSG00000198793 ENSG00000155792 ENSG00000168610 PMC7195637__F7 Regulation of mTOR on Th9 cell differentiation ENSG00000150907 ENSG00000137265 ENSG00000155792 PMC7195637__F6 Regulation of mTOR on Treg cell differentiation ENSG00000150907 ENSG00000155792 ENSG00000049768 PMC8217358__F1 Gene- and RNAi-Activated Scaffolds for Bone Tissue Engineering: Current Progress and Future Directions ENSG00000170365 ENSG00000237834 PMC8408623__F2 Medical gas plasma-stimulated wound healing: Evidence and mechanisms ENSG00000181019 ENSG00000100387 ENSG00000079999 PMC7195637__F1 mTOR signaling pathway and its functions ENSG00000173599 ENSG00000155792 ENSG00000112561 PMC3260518__F1 Invisible hand: regulation of RHO GTPases by RHOGDIs ENSG00000070831 ENSG00000198742 ENSG00000163914 ENSG00000116237 PMC3066060__F2 Simplified schematic representation of the apoptosis pathway in mammals and Drosophila ENSG00000168040 ENSG00000026103 PMC7277693__F6 Upregulated genes (red boxes) related to ER-stress and leading to apoptosis and protein degradation ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000171791 ENSG00000127191 ENSG00000090520 ENSG00000135506 ENSG00000086232 ENSG00000086619 PMC7277693__F5 Schematic view of genes downregulated (green) and upregulated (red) in the biosynthesis and degradation pathway of cholesterol ENSG00000067064 ENSG00000110921 ENSG00000112972 ENSG00000138135 ENSG00000116133 ENSG00000172893 ENSG00000113161 ENSG00000052802 PMC10571764__F1 Therapeutic mechanisms involving elotuzumab and Anti-SLAMF3 in multiple myeloma (MM) ENSG00000026751 PMC6049001__F4 In vitro–transcribed guide RNAs trigger an innate immune response via the RIG-I pathway ENSG00000088888 ENSG00000276561 PMC8672419__F4 FcER1: A Novel Molecule Implicated in the Progression of Human Diabetic Kidney Disease ENSG00000169291 ENSG00000135605 ENSG00000010671 PMC8718643__F3 Research Progress on the Mechanism Between Polycystic Ovary Syndrome and Abnormal Endometrium ENSG00000136111 PMC6029133__F6 Cancer-related pathway-pathway relationships ENSG00000175054 ENSG00000186810 ENSG00000113520 ENSG00000166851 ENSG00000139687 ENSG00000121966 PMC3702532__F8 RNA Sequencing of the Human Milk Fat Layer Transcriptome Reveals Distinct Gene Expression Profiles at Three Stages of Lactation ENSG00000171302 PMC3702532__F7 RNA Sequencing of the Human Milk Fat Layer Transcriptome Reveals Distinct Gene Expression Profiles at Three Stages of Lactation ENSG00000104812 ENSG00000140992 ENSG00000002330 ENSG00000050748 ENSG00000198793 ENSG00000095015 ENSG00000169710 ENSG00000105647 ENSG00000141564 ENSG00000100485 ENSG00000196396 ENSG00000175634 ENSG00000115457 ENSG00000182473 ENSG00000165458 ENSG00000150907 ENSG00000146678 ENSG00000104365 ENSG00000171105 ENSG00000197081 ENSG00000100994 ENSG00000125733 ENSG00000143933 ENSG00000076555 ENSG00000160999 ENSG00000160691 ENSG00000101255 ENSG00000067606 ENSG00000177606 ENSG00000079435 PMC3977809__F2 EGAN analysis showing all the differentially expressed enriched pathway genes ENSG00000169248 ENSG00000163629 ENSG00000284770 ENSG00000142273 ENSG00000170242 ENSG00000117154 ENSG00000198964 ENSG00000292032 ENSG00000186847 ENSG00000110148 ENSG00000122756 ENSG00000114107 ENSG00000115138 ENSG00000163933 ENSG00000163684 ENSG00000086200 ENSG00000182628 ENSG00000101639 ENSG00000115163 ENSG00000108055 ENSG00000074695 ENSG00000187790 ENSG00000197905 ENSG00000108342 ENSG00000135413 ENSG00000277804 ENSG00000140259 ENSG00000112039 ENSG00000124233 ENSG00000157005 ENSG00000102854 ENSG00000178919 ENSG00000139219 ENSG00000174307 ENSG00000139330 ENSG00000115884 ENSG00000253710 ENSG00000172236 ENSG00000139133 ENSG00000180855 ENSG00000165392 ENSG00000132692 ENSG00000164362 ENSG00000197299 ENSG00000133661 ENSG00000162692 ENSG00000006016 PMC5337695__F2 EGR1 regulations and functions in the central nervous system in the context of synaptic plasticity ENSG00000065609 ENSG00000176884 ENSG00000135823 ENSG00000198576 ENSG00000138386 ENSG00000099940 ENSG00000274542 PMC4886063__F7 P2-dependent activation of the IRK/PI3K/Akt pathway PMC3974825__F1 Emerging roles of Jab1/CSN5 in DNA damage response, DNA repair, and cancer ENSG00000149311 ENSG00000175054 ENSG00000051180 PMC7532256__F2 Monoclonal Antibody-Based Treatments for Neuromyelitis Optica Spectrum Disorders: From Bench to Bedside ENSG00000177455 ENSG00000112715 ENSG00000171885 PMC3940258__F5 Paramyxovirus inhibition of IFN signaling pathways ENSG00000105397 ENSG00000115415 PMC1716201__F1 Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737 ENSG00000100290 ENSG00000002330 ENSG00000171791 ENSG00000135116 ENSG00000104081 PMC8669959__F7 Storax, A Promising Botanical Medicine for Treating Cardio-Cerebrovascular Diseases: A Review ENSG00000239732 ENSG00000112715 PMC7694131__F1 Canonical and non-canonical Wnt signaling pathways ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9160188__F3 Nonapoptotic Programmed Cell Death — Ferroptosis, Necroptosis, and Pyroptosis — in Pancreatic Ductal Adenocarcinoma Treatment ENSG00000278718 ENSG00000162711 PMC7373899__F2 Disentangling molecular mechanisms regulating sensitization of interferon alpha signal transduction ENSG00000184979 ENSG00000168310 PMC8214274__F2 Histone dynamics during DNA replication stress ENSG00000021776 ENSG00000164053 ENSG00000138346 ENSG00000080345 ENSG00000130997 ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000166508 ENSG00000139618 ENSG00000175054 ENSG00000168283 ENSG00000107290 ENSG00000144554 ENSG00000121481 ENSG00000197299 ENSG00000051180 ENSG00000122008 PMC5686050__F1 Interleukin-4 (IL-4) and interleukin-13 (IL-13) receptor complexes ENSG00000124102 ENSG00000123496 ENSG00000131724 ENSG00000105639 PMC7596939__F3 MiRNA regulation in signaling processes in obesity, liver and uterine cancers ENSG00000137713 ENSG00000117020 ENSG00000077150 ENSG00000172380 ENSG00000002330 ENSG00000081913 ENSG00000141480 ENSG00000177606 ENSG00000095015 ENSG00000150093 ENSG00000037280 ENSG00000118971 PMC7407311__F7 CXCL14 regulates hESC self-renewal and cell cycle through IGF-1R signaling pathway ENSG00000145824 ENSG00000105810 ENSG00000140443 PMC4358129__F11 MiR-199a-5p in smooth muscle differentiation and hypertrophy ENSG00000141052 ENSG00000283060 ENSG00000168646 ENSG00000136826 PMC7660801__F5 Right Ventricle Has Normal Myofilament Function But Shows Perturbations in the Expression of Extracellular Matrix Genes in Patients With Tetralogy of Fallot Undergoing Pulmonary Valve Replacement ENSG00000039537 ENSG00000009724 ENSG00000113600 ENSG00000203710 ENSG00000244731 ENSG00000165471 ENSG00000062485 ENSG00000236625 PMC3343154__F3 Mammalian unfolded protein response (UPR) pathways ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC8469536__F2 From the Evasion of Degradation to Ubiquitin-Dependent Protein Stabilization ENSG00000063978 ENSG00000144895 ENSG00000168036 PMC7037239__F1 IL-15 signaling pathways ENSG00000033327 ENSG00000198793 ENSG00000105639 ENSG00000168610 PMC4722981__F1 The mechanism of TRPC5 in mediating chemoresistance ENSG00000168036 ENSG00000072315 PMC4627418__F5 Cytokine receptor interaction network for GBM survival ENSG00000182578 ENSG00000104689 ENSG00000115008 ENSG00000112964 ENSG00000138798 ENSG00000120889 ENSG00000163736 ENSG00000111321 ENSG00000187266 ENSG00000121807 ENSG00000168811 ENSG00000273936 ENSG00000064300 ENSG00000121966 ENSG00000161955 ENSG00000226275 ENSG00000049130 ENSG00000137077 ENSG00000125538 ENSG00000184371 ENSG00000164400 ENSG00000112115 ENSG00000146648 ENSG00000141655 PMC12069117__F21 TREM2 signalling pathways ENSG00000110395 ENSG00000213658 ENSG00000291971 ENSG00000043462 ENSG00000137845 ENSG00000100485 ENSG00000086730 ENSG00000141968 PMC3164671__F5 Genome-Wide Identification of Bcl11b Gene Targets Reveals Role in Brain-Derived Neurotrophic Factor Signaling ENSG00000162772 PMC10451232__F4 Transcriptomic changes in p53-associated apoptotic signaling in burn-wound-healing pathway ENSG00000132906 ENSG00000019991 ENSG00000109320 ENSG00000177606 ENSG00000084110 ENSG00000120868 ENSG00000171791 ENSG00000064012 ENSG00000164305 ENSG00000277943 PMC8684614__F4 Epigenetic modification and BRAF gene mutation in thyroid carcinoma ENSG00000157764 PMC2593440__F3 Network of differentially expressed genes in the cell cycle control pathway in sorted R1/R2 Eklf−/− E13.5 fetal liver cells ENSG00000143799 ENSG00000228716 ENSG00000142192 ENSG00000165891 ENSG00000164109 ENSG00000291803 ENSG00000110931 ENSG00000163453 ENSG00000186298 ENSG00000134480 ENSG00000104064 ENSG00000139219 ENSG00000281766 ENSG00000103479 ENSG00000117036 ENSG00000135446 ENSG00000184203 ENSG00000183864 ENSG00000105810 ENSG00000080839 ENSG00000282899 PMC10299161__F4 Oxidative stress promotes the activation of programmed cell death initiated by intrinsic apoptotic signaling in the mitochondria or extrinsic apoptotic signaling by death receptor pathways in CRC cells ENSG00000002330 PMC6165336__F11 AAP-H and the PI3K/AKT/mTOR signaling pathway ENSG00000002330 ENSG00000198793 PMC5290952__F10 Proposed mechanism whereby RET/PTC3 regulates IDO1 expression in thyroid cancer cells ENSG00000115415 ENSG00000291971 ENSG00000125347 PMC7937358__F3 Immuno-pathogenicity of MERS-CoV ENSG00000197635 PMC6951458__F1 Mnk 1/2 signaling ENSG00000136158 PMC9523788__F2 Innate and adaptive immune evasion by dengue virus ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC12073561__F5 Small RNAs are involved in the regulation of plant female gametophyte development ENSG00000127445 ENSG00000134287 ENSG00000165527 ENSG00000134698 PMC12224056__F3 Schematic representations of the effects of iron chelation on CRC pathogenesis and progression ENSG00000149311 ENSG00000175054 ENSG00000134982 ENSG00000168036 ENSG00000067900 PMC5478005__F1 Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000167074 PMC12224056__F4 TRAIL‐mediated apoptosis pathway ENSG00000168040 PMC6060673__F1 Immunomodulatory approaches for the treatment and prevention of neonatal sepsis ENSG00000170458 ENSG00000125538 ENSG00000169429 ENSG00000136869 PMC4106090__F1 N-glycosylation pathway ENSG00000070444 ENSG00000172469 ENSG00000089597 PMC4143615__F2 Top-ranked enriched canonical pathway identified using IPA, the T-cell receptor signaling pathway ENSG00000291603 ENSG00000107338 ENSG00000110395 ENSG00000213658 ENSG00000095321 ENSG00000010810 ENSG00000113263 ENSG00000135605 PMC4106090__F3 GPI anchorage pathway ENSG00000104626 ENSG00000275600 ENSG00000143315 ENSG00000108474 ENSG00000100564 ENSG00000197563 ENSG00000165282 PMC2972271__F5 The metabolite NAD+ oscillates in a circadian manner ENSG00000105835 ENSG00000096717 PMC4222698__F2 Clinical utility of pharmacogenomics in the management of hepatitis C ENSG00000088888 ENSG00000090402 ENSG00000115415 PMC4222698__F1 Clinical utility of pharmacogenomics in the management of hepatitis C ENSG00000292250 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000107201 ENSG00000276561 ENSG00000174611 PMC2860309__F1 EDA signaling ENSG00000099866 ENSG00000138795 ENSG00000140564 ENSG00000186197 ENSG00000135960 ENSG00000104371 ENSG00000173039 ENSG00000164690 ENSG00000175104 PMC6768854__F7 MiR-708 expression gradient is reduced during the transformation from normal prostate epithelial cells through adenocarcinoma cells to NEPC ENSG00000149212 ENSG00000150907 ENSG00000168036 ENSG00000196628 PMC11497390__F7 Rosmarinic acid promotes cartilage regeneration through Sox9 induction via NFKB pathway inhibition in mouse osteoarthritis progression ENSG00000139219 ENSG00000125398 ENSG00000149968 ENSG00000157766 ENSG00000125538 PMC5264327__F8 Working model representing the proposed signaling pathways induced by vitamin D signaling in regulating skeletal muscle mass ENSG00000168610 PMC3477504__F3 Cytokinesis Mechanics and Mechanosensing ENSG00000140575 ENSG00000136883 ENSG00000149503 PMC3579404__F1 Conserved Wnt pathway branches and components ENSG00000071564 ENSG00000138795 ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000070831 ENSG00000134982 ENSG00000064393 ENSG00000163914 PMC8026309__F6 The mechanism through which CTRE inhibits MGO-induced tubular cell inflammation and oxidative stress by upregulating the Nrf2-antioxidant enzyme pathway and downregulating the PKCB/NOX4 signaling ENSG00000181019 ENSG00000086991 PMC7946919__F8 Typing FGFR2 translocation determines the response to targeted therapy of intrahepatic cholangiocarcinomas ENSG00000066468 PMC10039784__F1 Deficient radiation transcription response in COVID-19 patients ENSG00000184990 ENSG00000132906 ENSG00000039537 ENSG00000196470 ENSG00000171791 ENSG00000164305 ENSG00000149311 ENSG00000175054 ENSG00000136997 ENSG00000042286 ENSG00000123374 ENSG00000112378 ENSG00000064012 ENSG00000026103 PMC3252833__F3 Sensitisation of type 2 cancer cells towards DR-induced killing by synthetic IAP antagonists ENSG00000164305 PMC6051204__F1 Folate‐mediated one‐carbon metabolism, links to methylation reactions and nucleotide synthesis (by Cheng TY et al ENSG00000284320 ENSG00000228716 ENSG00000065911 ENSG00000100714 ENSG00000173638 ENSG00000124275 ENSG00000185339 ENSG00000137563 ENSG00000116984 PMC3252833__F1 Fas-induced apoptotic signalling pathway ENSG00000132906 ENSG00000171791 ENSG00000164305 ENSG00000026103 PMC6854237__F3 Microbiota-triggered EMT via E-cadherin/Beta-catenin ENSG00000134982 ENSG00000168036 PMC3900498__F1 Yin and Yang of PI3K vs PTEN in the regulation of beta cell proliferation ENSG00000198793 PMC5449449__F2 Integration of metabolic and fatty acids (FAs) metabolizing enzymes pathway in mitochondrial dysregulation, fibrotic hypertrophy, and chronic inflammation ENSG00000150907 ENSG00000169047 PMC7248192__F2 Hyperglycemia-induced oxidative stress impairs nitric oxide signaling ENSG00000162711 ENSG00000265972 ENSG00000162692 PMC11008464__F1 New insight into arginine and tryptophan metabolism in macrophage activation during tuberculosis ENSG00000185818 ENSG00000065833 ENSG00000122966 ENSG00000172005 ENSG00000124523 ENSG00000118520 ENSG00000036473 ENSG00000115419 PMC5098220__F3 Multi-label ℓ2-regularized logistic regression for predicting activation/inhibition relationships in human protein-protein interaction networks ENSG00000134460 ENSG00000121716 ENSG00000169047 ENSG00000108443 ENSG00000171791 ENSG00000172216 ENSG00000084676 ENSG00000292332 ENSG00000115594 ENSG00000087095 ENSG00000147168 ENSG00000115590 ENSG00000213341 ENSG00000110395 ENSG00000123609 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000135605 ENSG00000168685 ENSG00000120833 ENSG00000033327 ENSG00000002330 ENSG00000198053 ENSG00000153094 ENSG00000198793 ENSG00000115904 ENSG00000105647 ENSG00000176105 ENSG00000099942 ENSG00000135341 ENSG00000141968 ENSG00000121966 ENSG00000089159 ENSG00000179295 ENSG00000169967 ENSG00000157557 ENSG00000182511 ENSG00000125538 ENSG00000124181 ENSG00000115008 ENSG00000100906 ENSG00000109320 ENSG00000269335 ENSG00000173039 ENSG00000105639 ENSG00000006062 ENSG00000168610 ENSG00000160691 ENSG00000107338 ENSG00000115415 ENSG00000067606 ENSG00000010810 ENSG00000177606 ENSG00000164362 ENSG00000171608 ENSG00000136689 PMC5555610__F2 RAS Proteins and Their Regulators in Human Disease ENSG00000205517 ENSG00000280962 ENSG00000111344 ENSG00000115904 ENSG00000141068 ENSG00000155903 ENSG00000169032 ENSG00000121879 ENSG00000157557 ENSG00000107263 ENSG00000197283 ENSG00000126458 ENSG00000133818 ENSG00000109756 ENSG00000157764 ENSG00000152689 ENSG00000281877 ENSG00000171777 ENSG00000177189 ENSG00000110395 ENSG00000105122 ENSG00000171435 ENSG00000177606 ENSG00000280477 ENSG00000136848 ENSG00000171608 PMC5098220__F2 Multi-label ℓ2-regularized logistic regression for predicting activation/inhibition relationships in human protein-protein interaction networks ENSG00000104884 ENSG00000112576 ENSG00000291971 ENSG00000010017 ENSG00000105647 ENSG00000277273 ENSG00000134480 ENSG00000089159 ENSG00000012048 ENSG00000159216 ENSG00000169750 ENSG00000244405 ENSG00000150907 ENSG00000185591 ENSG00000137843 ENSG00000124664 ENSG00000139687 ENSG00000275045 ENSG00000005339 ENSG00000033800 ENSG00000126457 ENSG00000101224 ENSG00000177606 ENSG00000146648 ENSG00000132341 PMC4084718__F4 Contextualizing Sharpin within the NFKB pathway by comparative analysis of mutant transcriptomes ENSG00000150782 ENSG00000125826 ENSG00000115008 ENSG00000100906 ENSG00000172936 ENSG00000175104 PMC11396780__F9 Integration of Transcriptomics and Metabolomics Reveals the Antitumor Mechanism of Protopanaxadiol Triphenylphosphate Derivative in Non-Small-Cell Lung Cancer ENSG00000198793 ENSG00000077463 ENSG00000166986 ENSG00000142082 ENSG00000146648 ENSG00000141526 PMC5355171__F2 Deciphering the link between PI3K and PAK: An opportunity to target key pathways in pancreatic cancer? ENSG00000002330 ENSG00000070831 PMC5098220__F1 Multi-label ℓ2-regularized logistic regression for predicting activation/inhibition relationships in human protein-protein interaction networks ENSG00000198053 ENSG00000010017 ENSG00000105647 ENSG00000155974 ENSG00000160999 ENSG00000064300 ENSG00000179295 ENSG00000156299 ENSG00000010810 ENSG00000071051 ENSG00000088538 ENSG00000101134 ENSG00000134243 ENSG00000175104 ENSG00000120251 ENSG00000105662 PMC2528242__F1 Peroxisome proliferator-activated receptorG and ligands: pathways and functions ENSG00000135218 ENSG00000177606 ENSG00000185591 ENSG00000168610 PMC3998676__F1 ADVANCING AGE IS ASSOCIATED WITH GENE EXPRESSION CHANGES RESEMBLING mTOR INHIBITION: EVIDENCE FROM TWO HUMAN POPULATIONS ENSG00000177169 ENSG00000169047 ENSG00000118515 ENSG00000168610 ENSG00000276561 PMC5648159__F6 Short-chain fatty acid receptors inhibit invasive phenotypes in breast cancer cells ENSG00000131023 PMC7589994__F1 Role of the best-characterized HDACs in liver fibrosis ENSG00000105329 ENSG00000095739 ENSG00000196591 ENSG00000048052 ENSG00000136869 ENSG00000096717 PMC4376617__F7 The role of T cells in the anabolic activity of iPTH in trabecular bone ENSG00000152266 ENSG00000281324 ENSG00000162337 ENSG00000169884 PMC9647849__F4 Mass spectrometry‐based proteomics analysis of human globus pallidus from progressive supranuclear palsy patients discovers multiple disease pathways ENSG00000069482 ENSG00000197471 ENSG00000156026 ENSG00000281879 PMC5338674__F7 Model for Pol E function in plant DDR ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000291803 ENSG00000051180 PMC5129950__F1 miR-590 promotes cell proliferation and invasion in T-cell acute lymphoblastic leukaemia by inhibiting RB1 ENSG00000149311 ENSG00000175054 ENSG00000168283 ENSG00000101945 ENSG00000123374 ENSG00000169375 PMC7028499__F7 21-BENZYLIDENE DIGOXIN DECREASES PROLIFERATION BY INHIBITING THE EGFR/ERK SIGNALING PATHWAY AND INDUCES APOPTOSIS IN HELA CELLS ENSG00000132906 ENSG00000146648 ENSG00000164305 PMC6071020__F5 Neurotrophin signaling pathway and genes involved in the significant gene links (marked in red box) ENSG00000169291 ENSG00000090402 ENSG00000002330 ENSG00000163914 ENSG00000175104 PMC6349306__F1 Epicatechin modulates stress-resistance in C. elegans via insulin/IGF-1 signaling pathway ENSG00000118515 PMC8741964__F1 Impact of bariatric surgery on serum tryptophan–kynurenine pathway metabolites PMC4111852__F3 PI3K pathway in different breast cancer subtypes ENSG00000136869 PMC5428929__F6 Genome-wide transcriptome profiling of radish (Raphanus sativus L.) in response to vernalization ENSG00000163435 ENSG00000203783 PMC7373816__F2 Metabolic regulation of the Hippo-YAP signaling network ENSG00000126016 ENSG00000164430 ENSG00000147162 ENSG00000198793 ENSG00000150457 ENSG00000165757 ENSG00000131023 PMC7373816__F1 Hippo-YAP signaling network ENSG00000087095 ENSG00000126016 ENSG00000291971 ENSG00000277273 ENSG00000131023 PMC8655512__F2 Progranulin as a Potential Therapeutic Target in Immune-Mediated Diseases ENSG00000105664 ENSG00000239732 ENSG00000277804 ENSG00000184481 ENSG00000168610 PMC3485747__F1 Glutamine:fructose-6-phosphate amidotransferase 1 (GFPT1)–mediated MTOR signaling pathway affected by glucose and fructose in porcine trophectoderm cells ENSG00000198380 ENSG00000198793 ENSG00000187840 PMC7429631__F2 Profilin can be phosphorylated at S137 by Rho associated kinase (ROCK) downstream of vascular endothelial growth factor (VEGF) signalling, reducing actin polymerisation rates ENSG00000291971 ENSG00000163914 PMC7429631__F1 Profilin interactions in the membrane ENSG00000138798 ENSG00000198793 PMC7300907__F10 Increasing host cellular receptor—angiotensin‐converting enzyme 2 expression by coronavirus may facilitate 2019‐nCoV (or SARS‐CoV‐2) infection ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000130234 ENSG00000168610 ENSG00000164342 ENSG00000142166 PMC8323830__F2 Exploiting DNA repair pathways for tumor sensitization, mitigation of resistance, and normal tissue protection in radiotherapy ENSG00000012048 ENSG00000138346 ENSG00000051180 ENSG00000139618 PMC3187694__F1 Simplified model of autophagy ENSG00000198793 ENSG00000145782 PMC4707157__F1 Mechanisms by which mitochondrial DNA activates innate immunity ENSG00000239732 ENSG00000125538 PMC3291562__F4 Function-Based Discovery of Significant Transcriptional Temporal Patterns in Insulin Stimulated Muscle Cells ENSG00000104812 ENSG00000140992 ENSG00000065675 ENSG00000136111 ENSG00000169047 ENSG00000108443 ENSG00000142273 ENSG00000165527 ENSG00000100485 ENSG00000173327 ENSG00000175634 ENSG00000163558 ENSG00000148082 ENSG00000106070 ENSG00000220205 ENSG00000100219 ENSG00000196455 ENSG00000065559 ENSG00000132356 ENSG00000132639 ENSG00000187840 ENSG00000104814 ENSG00000110395 ENSG00000197879 ENSG00000133124 ENSG00000079435 ENSG00000152556 ENSG00000130758 ENSG00000050748 ENSG00000288174 ENSG00000136854 ENSG00000095015 ENSG00000115904 ENSG00000141639 ENSG00000168067 ENSG00000197442 ENSG00000142733 ENSG00000105647 ENSG00000169032 ENSG00000166484 ENSG00000069956 ENSG00000139625 ENSG00000135341 ENSG00000121879 ENSG00000196396 ENSG00000137764 ENSG00000116266 ENSG00000115290 ENSG00000166592 ENSG00000168118 ENSG00000179295 ENSG00000169967 ENSG00000073803 ENSG00000011566 ENSG00000101049 ENSG00000141503 ENSG00000143761 ENSG00000040933 ENSG00000129946 ENSG00000165458 ENSG00000197594 ENSG00000024422 ENSG00000027075 ENSG00000171105 ENSG00000104365 ENSG00000111713 ENSG00000006062 ENSG00000160691 ENSG00000185386 ENSG00000101255 ENSG00000067606 ENSG00000162409 ENSG00000177606 ENSG00000154415 ENSG00000188130 ENSG00000171608 ENSG00000105723 PMC8323830__F1 Exploiting DNA repair pathways for tumor sensitization, mitigation of resistance, and normal tissue protection in radiotherapy ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000051180 ENSG00000139618 PMC7115894__F4 Effect of elevated Na+ on cancer progression and the tumour microenvironment ENSG00000160584 ENSG00000113520 ENSG00000115419 PMC8277109__F2 Nutrient signaling pathways altered by methionine restriction (MR) ENSG00000128272 ENSG00000105550 PMC9331286__F1 T Helper 22 Cells in Dermatological Disorders ENSG00000105397 ENSG00000115415 ENSG00000125538 ENSG00000198793 ENSG00000184451 ENSG00000168610 ENSG00000112486 ENSG00000106546 PMC5683188__F1 Localization of key lipids and enzymes, designated by the genes encoding them, in different cellular compartments in S ENSG00000163624 ENSG00000146005 ENSG00000173599 PMC3983226__F1 Predicting Kinase Activity in Angiotensin Receptor Phosphoproteomes Based on Sequence-Motifs and Interactions ENSG00000002330 PMC9035589__F9 Microbial Utilization of Next-Generation Feedstocks for the Biomanufacturing of Value-Added Chemicals and Food Ingredients ENSG00000008130 ENSG00000062485 ENSG00000026103 PMC9105930__F1 Insight into the Role of the PI3K/Akt Pathway in Ischemic Injury and Post-Infarct Left Ventricular Remodeling in Normal and Diabetic Heart ENSG00000167468 ENSG00000125538 ENSG00000168404 PMC3632731__F2 Network 2 (metabolic disease, renal and urologic disease, and molecular transport) generated by pathway analysis of the hot list ENSG00000292348 ENSG00000078549 ENSG00000142192 ENSG00000118785 ENSG00000198838 ENSG00000167074 ENSG00000076706 ENSG00000119681 ENSG00000171051 ENSG00000172037 PMC3632731__F1 Network 1 (antigen presentation, cell-mediated immune response, and humoral immune response) generated by pathway analysis of the hot list ENSG00000039537 ENSG00000142192 ENSG00000244731 ENSG00000166278 ENSG00000122194 ENSG00000079557 ENSG00000236625 ENSG00000175054 ENSG00000288427 ENSG00000292234 ENSG00000274334 ENSG00000175899 ENSG00000198125 PMC8669501__F1 SNAIL1: Linking Tumor Metastasis to Immune Evasion ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000164690 PMC11840414__F1 Steroidal glycoalkaloids biosynthetic pathway in potato (Solanum tuberosum) and tomato (Solanum lycopersicum) ENSG00000229859 ENSG00000115271 PMC10986082__F2 Multiple mechanisms of environmental stress regulating CSC transcription A The immune cells in TME activate the STAT, Wnt, AKT and Notch pathway of CSC by mainly releasing cytokines (IL-6) and inducing contact ENSG00000133110 ENSG00000198793 ENSG00000026508 ENSG00000168036 PMC8836862__F10 Blood Bacteria-Free DNA in Septic Mice Enhances LPS-Induced Inflammation in Mice through Macrophage Response ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC10986082__F1 Targeting TFs in CSC from multiple perspectives A Directly blocking the combination of TFs and DNA: mainly through epigenetic mechanisms ENSG00000026508 ENSG00000168036 ENSG00000128602 PMC6304621__F3 General representation of the signaling pathways involved in CBD anticancer mediated effects ENSG00000187688 ENSG00000196689 PMC6215866__F3 Transforming growth factor‐beta pathway and the Wnt/Beta‐catenin pathway ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC6215866__F2 Positive feedback loop between the Rspo/Lgr5 pathway and the Wnt/B‐catenin pathway ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000108375 PMC6215866__F1 Mouse breast carcinogenesis induced by the activation of the canonical Wnt pathway ENSG00000281324 ENSG00000162337 ENSG00000136997 ENSG00000168036 PMC5854685__F8 Pathway from hippocampal molecular defects to AD neurotoxicity ENSG00000145920 PMC6328535__F6 Dacarbazine and PLX4032 cross-resistance emerges via distinct MAPK-dependent and -independent pathway activation ENSG00000157764 ENSG00000198793 ENSG00000134853 PMC5215656__F6 Natural Flavonoid Fisetin Inhibits Cellular Proliferation of Hepatic, Colorectal, and Pancreatic Cancer Cells through Modulation of Multiple Signaling Pathways ENSG00000125740 ENSG00000149269 ENSG00000168036 ENSG00000084774 PMC11085123__F1 Biosynthetic pathway of terpenoids (A), alkaloids (B), and phenylpropanoids (C) in plants ENSG00000110921 ENSG00000197429 PMC7598160__F3 Glycolysis and oxidative phosphorylation in the retina ENSG00000157184 ENSG00000126266 PMC6471220__F3 Transcriptional effects in zebrafish liver after feeding with 25% of maize substitution ENSG00000151224 ENSG00000139209 ENSG00000171759 ENSG00000103507 ENSG00000112394 ENSG00000116761 ENSG00000026103 ENSG00000119125 PMC3628745__F2 New signaling network for melanoma ENSG00000166869 ENSG00000162552 ENSG00000066468 ENSG00000157404 ENSG00000185634 ENSG00000049130 ENSG00000041982 ENSG00000157764 ENSG00000291971 ENSG00000134982 ENSG00000146648 PMC8230717__F3 Genetic Susceptibility to Periodontal Disease in Down Syndrome: A Case-Control Study ENSG00000002330 PMC9386448__F2 Phytochemical and pharmacological profile of taraxasterol ENSG00000278718 ENSG00000162711 ENSG00000125538 ENSG00000198793 ENSG00000172936 ENSG00000136869 PMC8230717__F2 Genetic Susceptibility to Periodontal Disease in Down Syndrome: A Case-Control Study ENSG00000087095 ENSG00000179091 ENSG00000123374 PMC6062380__F4 Gender specific differences in the liver proteome of rats exposed to short term and low-concentration hexabromocyclododecane (HBCD) †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6tx00166a ENSG00000137561 ENSG00000113889 ENSG00000013016 ENSG00000105854 ENSG00000104969 ENSG00000167658 ENSG00000163631 ENSG00000160752 ENSG00000292086 ENSG00000005421 ENSG00000171759 ENSG00000179348 ENSG00000114115 ENSG00000119125 PMC2927527__F2 “Mens Sana In Corpore Sano”: Exercise and Hypothalamic ER Stress ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC3416961__F1 Simplified diagram depicting Ras signaling and crosstalk with PI3 kinase- Akt pathway in leukemia ENSG00000122025 ENSG00000186716 ENSG00000198793 PMC3274818__F1 Activation of an RTK induces dimerization and downstream phosphorylation of non-receptor tyrosine kinases ENSG00000033327 ENSG00000070831 ENSG00000163914 ENSG00000146648 ENSG00000196712 PMC9274112__F3 HMGB1/TLR4 and IL-1B/IL-1R1 Signaling Pathways in Epilepsy ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC9274112__F2 HMGB1/TLR4 and IL-1B/IL-1R1 Signaling Pathways in Epilepsy ENSG00000278718 ENSG00000172936 ENSG00000175104 ENSG00000115594 PMC9274112__F1 HMGB1/TLR4 and IL-1B/IL-1R1 Signaling Pathways in Epilepsy ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC3394505__F9 Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas ENSG00000134982 PMC8919059__F6 Genomic And Tumor Microenvironment Differences Between Cell Cycle Progression Pathway Altered/Non-Altered Patients With Lung Adenocarcinoma ENSG00000124092 ENSG00000123999 ENSG00000115008 ENSG00000187268 ENSG00000124882 ENSG00000141639 ENSG00000276051 ENSG00000173809 ENSG00000179593 ENSG00000291501 ENSG00000109132 ENSG00000292120 PMC8919059__F5 Genomic And Tumor Microenvironment Differences Between Cell Cycle Progression Pathway Altered/Non-Altered Patients With Lung Adenocarcinoma ENSG00000144834 ENSG00000163216 ENSG00000241794 ENSG00000106927 ENSG00000163631 ENSG00000186081 ENSG00000104435 ENSG00000110148 ENSG00000278767 ENSG00000188257 ENSG00000196361 ENSG00000176165 ENSG00000251493 ENSG00000072080 ENSG00000100285 ENSG00000159516 ENSG00000244094 ENSG00000203785 ENSG00000110680 ENSG00000168878 ENSG00000132639 ENSG00000132693 ENSG00000107295 ENSG00000113905 ENSG00000069482 ENSG00000163630 ENSG00000145321 ENSG00000133661 ENSG00000171759 ENSG00000080618 ENSG00000136872 PMC4350422__F1 Immunologic manifestations of autophagy ENSG00000177169 ENSG00000183735 ENSG00000239732 ENSG00000088888 PMC2947220__F8 Cytoplasmic p21 expression levels determine cisplatin resistance in human testicular cancer ENSG00000123374 ENSG00000026103 PMC9622808__F6 Schematic model ENSG00000135929 PMC545795__F3 Largest connected subgraph resulting from combined query on four pathways involved in carbohydrate metabolism: glycolysis/gluconeogenesis (red); pyruvate metabolism (yellow); TCA cycle (green); and the glyoxylate cycle (pink) ENSG00000122966 ENSG00000087842 ENSG00000169299 ENSG00000102977 PMC6829426__F13 A potato plant’s response to weak light and exogenous Ca2+ ENSG00000122966 ENSG00000166278 PMC4276148__F1 Regulation of miRNAs in NHL ENSG00000136997 ENSG00000096717 ENSG00000130508 PMC4896088__F1 Nodes of therapeutic blockade in the PI3K and other signaling pathways that synergize with BET inhibition ENSG00000109452 ENSG00000169047 ENSG00000136997 PMC3033967__F8 Structural Characterization of the Polar Lipids of Clostridium novyi NT. Further Evidence for a Novel Anaerobic Biosynthetic Pathway to Plasmalogens ENSG00000184207 ENSG00000182326 PMC2983087__F2 Mechanisms of double-strand break repair in somatic mammalian cells ENSG00000012048 ENSG00000083093 ENSG00000051180 ENSG00000139618 PMC3134378__F3 Regulation of HIF-1A by the PI3K pathway ENSG00000198793 ENSG00000140464 PMC5673087__F3 Diagrammatic representation of hypothesized molecular mechanism of LH signaling dysfunction in PCOS women modified from ENSG00000171105 ENSG00000141448 ENSG00000103460 ENSG00000111540 ENSG00000196712 PMC7450969__F4 Ribosomal/TRP53 pathway pattern mediated by Salmonella infection ENSG00000180210 ENSG00000198918 ENSG00000135446 ENSG00000132646 ENSG00000137575 ENSG00000139687 ENSG00000026103 PMC11672923__F8 Signaling pathways involved in adipocyte metabolic disorders caused by melatonin decline with aging and HFD in eWAT ENSG00000211445 ENSG00000162711 ENSG00000172216 ENSG00000100985 PMC8773898__F2 MicroRNAs and Long Non-Coding RNAs in Sarcopenia ENSG00000111049 ENSG00000122180 ENSG00000169047 ENSG00000081189 ENSG00000115461 PMC3134378__F2 Regulation of HIF-1A by the MAPK pathway ENSG00000157764 PMC5699945__F5 Proteomic Analysis of the Glutathione-Deficient LEGSKO Mouse Lens Reveals Activation of EMT Signaling, Loss of Lens Specific Markers, and Changes in Stress Response Proteins ENSG00000092621 ENSG00000097021 ENSG00000115419 PMC4500461__F2 Genome-Wide Identification of Differentially Expressed Genes Associated with the High Yielding of Oleoresin in Secondary Xylem of Masson Pine (Pinus massoniana Lamb) by Transcriptomic Analysis ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC7429854__F8 Yap haploinsufficiency leads to Müller cell dysfunction and late-onset cone dystrophy ENSG00000113070 ENSG00000146648 ENSG00000171885 PMC8920547__F4 Clinical Characteristics of Patients With IgG4-Related Disease Complicated by Hypocomplementemia ENSG00000039537 ENSG00000113600 ENSG00000134830 ENSG00000026751 ENSG00000166278 PMC3376391__F2 Strategies to decrease ongoing oxidant burden in chronic obstructive pulmonary disease ENSG00000105227 ENSG00000079999 PMC6536719__F5 EGL-9 inhibits the HIF-1 target NHR-57 from reducing RAS/MAPK signaling through a DELTA/NOTCH-induced negative feedback loop ENSG00000138798 ENSG00000146648 PMC11011857__F3 Genetic Signature of Human Pancreatic Cancer and Personalized Targeting ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC6120701__F3 Interleukin (IL)-2 signaling pathway ENSG00000100385 ENSG00000134460 ENSG00000105639 PMC10031116__F6 Extracellular matrix stiffness—The central cue for skin fibrosis ENSG00000137834 ENSG00000070831 ENSG00000175104 ENSG00000076604 PMC3723562__F7 Polyethyleneimine Mediated DNA Transfection in Schistosome Parasites and Regulation of the WNT Signaling Pathway by a Dominant-Negative SmMef2 ENSG00000048052 ENSG00000125084 PMC8776636__F1 Ovarian Biomechanics: From Health to Disease ENSG00000157404 ENSG00000145321 PMC10031116__F5 Extracellular matrix stiffness—The central cue for skin fibrosis ENSG00000291971 ENSG00000198793 ENSG00000163914 ENSG00000132478 ENSG00000150457 ENSG00000171621 ENSG00000131023 ENSG00000197702 ENSG00000076604 PMC5883129__F1 Ubiquitin cascade ENSG00000175104 ENSG00000116525 PMC4927085__F8 Long noncoding RNA LINP1 regulates double strand DNA break repair in triple negative breast cancer ENSG00000149311 ENSG00000146648 PMC11794838__F9 HU protecting against DKD in this study ENSG00000162692 PMC4418220__F9 Crystalline silica-induced leukotrieneB4-dependent inflammation promotes lung tumor growth ENSG00000081041 ENSG00000062485 PMC8802208__F1 DSB repair pathway choice ENSG00000143799 ENSG00000012048 ENSG00000039650 ENSG00000165392 ENSG00000051180 ENSG00000139618 PMC8602044__F4 Plasma triacylglycerols are biomarkers of Beta-cell function in mice and humans ENSG00000163686 ENSG00000149084 ENSG00000140740 ENSG00000130414 ENSG00000162139 ENSG00000139180 ENSG00000128609 ENSG00000165914 ENSG00000203859 ENSG00000026652 ENSG00000160194 ENSG00000112695 ENSG00000147684 ENSG00000008513 ENSG00000156467 ENSG00000126267 ENSG00000004779 ENSG00000126091 ENSG00000178127 ENSG00000100422 ENSG00000198189 ENSG00000136521 ENSG00000127184 ENSG00000131174 ENSG00000154217 ENSG00000116459 ENSG00000065518 ENSG00000186010 ENSG00000189043 ENSG00000119013 ENSG00000168350 ENSG00000155099 PMC5332470__F1 T cell differentiation and the emergence of CMV-induced T cell phenotypes ENSG00000139193 ENSG00000126353 PMC4509649__F3 Trade-Off between Growth and Carbohydrate Accumulation in Nutrient-Limited Arthrospira sp. PCC 8005 Studied by Integrating Transcriptomic and Proteomic Approaches ENSG00000143194 ENSG00000197713 ENSG00000134982 PMC11913853__F12 Differentially expressed genes implicated as top candidates for mediating the effect of selective breeding on behavior are often regulators of bioenergetic function ENSG00000175536 ENSG00000105699 ENSG00000156026 ENSG00000140527 ENSG00000105953 ENSG00000175567 ENSG00000197912 PMC5226821__F13 m6A-Driver: Identifying Context-Specific mRNA m6A Methylation-Driven Gene Interaction Networks ENSG00000105329 ENSG00000099942 ENSG00000112715 ENSG00000124762 ENSG00000179295 ENSG00000182004 ENSG00000136997 ENSG00000077312 ENSG00000130520 ENSG00000105810 ENSG00000084463 ENSG00000140443 ENSG00000277707 ENSG00000143549 ENSG00000198231 ENSG00000005339 ENSG00000165119 ENSG00000113649 ENSG00000109320 ENSG00000173039 ENSG00000179950 ENSG00000168040 ENSG00000063244 ENSG00000127191 ENSG00000076604 ENSG00000160691 ENSG00000085872 ENSG00000115524 ENSG00000110395 ENSG00000146648 PMC7823498__F1 Biological regulatory network (BRN) of IP3R with tumor suppressor and onco-proteins ENSG00000002330 ENSG00000198793 ENSG00000140464 PMC9404922__F1 Expression of Key Factors of the Hippo Signaling Pathway in Yak (Bos grunniens) Mammary Gland ENSG00000150457 ENSG00000131023 PMC6664075__F6 Hypothetical scenarios for the role of NGF after systemic oxidative stress ENSG00000023909 ENSG00000079999 PMC7435111__F1 Scheme of the heme biosynthesis pathway and membrane transporters ENSG00000131238 ENSG00000066926 ENSG00000126088 ENSG00000188690 ENSG00000118777 PMC10304648__F1 Detection of influenza A virus infection by pattern recognition receptors (PRRs) and NLRP3 inflammasome ENSG00000162711 ENSG00000088888 ENSG00000107201 ENSG00000276561 ENSG00000164342 PMC5820294__F1 Signaling pathways involved in the progression of extramammary Paget’s disease ENSG00000135446 ENSG00000170558 ENSG00000198793 ENSG00000102970 ENSG00000105810 ENSG00000121966 PMC7530063__F8 Vitamin C regulates Schwann cell myelination by promoting DNA demethylation of pro-myelinating genes ENSG00000197971 ENSG00000174607 ENSG00000105227 PMC6805690__F6 Noise-induced bistability and resolution of fate dichotomies ENSG00000148400 ENSG00000168036 ENSG00000096717 ENSG00000114315 PMC11708511__F7 Inhibition of triple-negative breast cancer growth via delphinidin-mediated suppression of the JAK2/STAT3/PD-L1 pathway ENSG00000168610 PMC8868551__F8A Folic Acid Homeostasis and Its Pathways Related to Hepatic Oxidation in Adolescent Rats Exposed to Binge Drinking ENSG00000228716 ENSG00000130649 ENSG00000086991 PMC3152951__F1 Interaction between HCV and Nuclear Receptor-mediated Pathways ENSG00000135218 ENSG00000167910 ENSG00000026103 PMC6805690__F4 Notch-induced autophagy and translational noise as destabilizers of cellular memory ENSG00000198793 ENSG00000136997 ENSG00000073111 ENSG00000076003 PMC6805690__F1 Notch pathway amplifies intrinsic noise by interactions that improve the efficiency of global protein synthesis ENSG00000136997 ENSG00000168036 ENSG00000114315 PMC7241336__F1 De Novo and Salvage Biosynthesis of Pyrimidine Nucleotides for Host and Viral RNA SynthesisGSK983 is a DHODH inhibitor ENSG00000162368 ENSG00000158825 ENSG00000143179 ENSG00000102967 ENSG00000084774 PMC6912418__F2 Mechanism and signaling pathways involved in mitochondrial adaptation in heart following exercise ENSG00000179862 PMC7073175__F10 The proposed mechanism underlying the TCEE-mediated anti-inflammatory effect in ECs and atherosclerosis ENSG00000162692 PMC4496299__F4 Epigenomic profiling in visceral white adipose tissue of offspring of mice exposed to late gestational sleep fragmentation ENSG00000116745 ENSG00000168530 ENSG00000108231 ENSG00000169047 ENSG00000285246 ENSG00000120437 ENSG00000158445 ENSG00000117713 ENSG00000138207 ENSG00000162139 ENSG00000167772 ENSG00000081913 ENSG00000115361 ENSG00000122971 ENSG00000132819 ENSG00000169174 PMC5994774__F5 Both mTOR and eIF4E phosphorylation are needed for polysomal recruitment of terminal oligopyrimidine messenger RNAs (TOP mRNA) ENSG00000101407 ENSG00000198793 ENSG00000155792 ENSG00000167965 PMC9313364__F7 Chemokine CCL4 Stimulates Angiopoietin-2 Expression and Angiogenesis via the MEK/ERK/STAT3 Pathway in Oral Squamous Cell Carcinoma ENSG00000091879 ENSG00000168610 ENSG00000277943 PMC5994774__F2 Scheme of PI3K/Akt/mTOR pathway depicting both complexes mTOR protein takes part in, mTORC1 and mTORC2 ENSG00000101407 ENSG00000198793 ENSG00000155792 PMC5883129__F2 Activation of NEMO and IKB by multiple signaling pathways ENSG00000173039 ENSG00000131323 ENSG00000175104 ENSG00000121060 PMC3753467__F1 IP3 instigates the activation and amplification of NFATc1 ENSG00000033327 ENSG00000197943 ENSG00000175104 ENSG00000131196 PMC9654807__F1 Prognostic and Therapeutic Potential of DNA Damage Repair Pathway Alterations and Homologous Recombination Deficiency in Lung Cancer ENSG00000143799 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000083093 ENSG00000051180 ENSG00000139618 PMC3886798__F3 Overview of the treatments in the context of previous results obtained with a test system based on the fluorescent reporter protein H 6-GFP-BD-CVIL in transgenic tobacco BY-2 cells PMC5552450__F6 Review of metabolic pathways activated in cancer cells as determined through isotopic labeling and network analysis ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC7416122__F2 Network of actual biochemical pathways constructed for S ENSG00000157554 ENSG00000143194 ENSG00000163624 ENSG00000074800 ENSG00000122966 ENSG00000172005 ENSG00000166123 ENSG00000128513 PMC2953497__F10 Tumor Necrosis FactorA Regulates Distinct Molecular Pathways and Gene Networks in Cultured Skeletal Muscle Cells ENSG00000106333 ENSG00000112972 ENSG00000100906 ENSG00000148400 ENSG00000164587 ENSG00000197728 ENSG00000177954 ENSG00000184916 ENSG00000072803 ENSG00000196313 ENSG00000012048 ENSG00000170365 ENSG00000077150 ENSG00000179772 ENSG00000198742 ENSG00000108306 ENSG00000278693 PMC9521401__F2 Dietary organosulfur compounds: Emerging players in the regulation of bone homeostasis by plant-derived molecules ENSG00000178860 ENSG00000170365 ENSG00000170909 ENSG00000181019 ENSG00000175793 ENSG00000164935 ENSG00000023909 ENSG00000131196 ENSG00000026103 ENSG00000143387 PMC4352427__F1 TRAIL-receptor mediated signalling pathways ENSG00000102871 ENSG00000171791 ENSG00000127191 PMC3843161__F3 Biomarker-guided translation of brain imaging into disease pathway models ENSG00000160789 ENSG00000275618 ENSG00000142973 ENSG00000156482 ENSG00000137802 ENSG00000114446 ENSG00000005175 ENSG00000143801 ENSG00000106070 ENSG00000137203 ENSG00000138768 ENSG00000185825 ENSG00000142192 ENSG00000182568 ENSG00000137275 ENSG00000065559 ENSG00000106100 ENSG00000069869 ENSG00000174059 ENSG00000140299 ENSG00000070831 ENSG00000291803 ENSG00000142347 ENSG00000111348 ENSG00000115290 ENSG00000160049 ENSG00000129219 ENSG00000150782 ENSG00000157927 ENSG00000077150 ENSG00000135457 ENSG00000135960 ENSG00000156299 ENSG00000197971 ENSG00000205155 ENSG00000128052 ENSG00000126458 ENSG00000253729 ENSG00000137673 ENSG00000100906 ENSG00000081237 ENSG00000173786 ENSG00000277804 ENSG00000182621 ENSG00000073921 ENSG00000168610 ENSG00000273936 ENSG00000160691 ENSG00000117020 ENSG00000010810 ENSG00000120471 ENSG00000100365 PMC10815595__F1 HBV-HCC pathways of top 10 downregulated miRNAs ENSG00000109320 ENSG00000291971 ENSG00000078668 ENSG00000177606 ENSG00000136997 ENSG00000123374 ENSG00000213341 ENSG00000171791 ENSG00000139687 ENSG00000124762 ENSG00000026103 PMC10815595__F2 HBV-HCC pathways of top 10 upregulated miRNA ENSG00000291971 ENSG00000167986 ENSG00000164305 PMC5479307__F4 There are similarities and significant differences in light and dopamine mediated phase regulation of the retinal clock in Xenopus leavis driving melatonin release and that in mice driving PER2∷luc expression ENSG00000122375 ENSG00000132326 ENSG00000124818 PMC7904891__F1 Susceptibility and protective factors of the lectin pathway of complement and complement receptors, for HBV infection per se and HBV infection/leprosy ENSG00000291559 ENSG00000203710 ENSG00000244731 ENSG00000236625 PMC7188667__F4 Emerging roles for UDP-glucuronosyltransferases in drug resistance and cancer progression ENSG00000197888 ENSG00000135226 ENSG00000196620 PMC5686097__F2 Cellular metabolic pathways driving mononuclear phagocyte inflammatory vs ENSG00000131473 ENSG00000125538 ENSG00000166278 ENSG00000159399 PMC7744503__F7 Mycoplasma pneumoniae lipids license TLR‐4 for activation of NLRP3 inflammasome and autophagy to evoke a proinflammatory response ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC8226122__F4 Thromboplasminflammation in COVID-19 Coagulopathy: Three Viewpoints for Diagnostic and Therapeutic Strategies ENSG00000009724 ENSG00000288512 ENSG00000122194 PMC4643722__F3 Supersaturation is a major driving force for protein aggregation in neurodegenerative diseases ENSG00000142192 ENSG00000168040 PMC6843432__F4 Coordinated contribution of ROS and BMPs to vascular diseases ENSG00000162551 ENSG00000086991 ENSG00000175104 ENSG00000164305 ENSG00000158125 PMC6278198__F5 Schematic summary of the possible mechanism for GLCCI1 in glucocorticoids pathway ENSG00000288269 ENSG00000125538 ENSG00000145321 ENSG00000106415 PMC6284329__F3 Decorin in cancer, based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) database (http://www.genome.jp/kegg‐bin/show_pathway?hsa05205) ENSG00000100234 ENSG00000087245 ENSG00000198793 ENSG00000136869 ENSG00000135404 ENSG00000100985 ENSG00000112715 ENSG00000146648 ENSG00000164305 PMC6843432__F1 BMP signaling pathways ENSG00000198793 ENSG00000173039 ENSG00000175104 PMC3753831__F2 ERK1/2-mediated regulation of the BCL2 protein family ENSG00000002330 ENSG00000157764 ENSG00000171791 ENSG00000104081 PMC3753831__F1 ERK1/2-mediated regulation of the G1-S phase transition ENSG00000157764 ENSG00000177606 ENSG00000136997 ENSG00000118971 PMC5977009__F1 Toll-like receptor signaling pathway ENSG00000183735 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC6335330__F1 Epigenetic regulation at the RUNX3 AS-associated locus ENSG00000137265 ENSG00000020633 ENSG00000168685 PMC3368734__F7 Functional interaction network analysis of genes with enriched expression (EE) and differential splicing (DS) in the placenta ENSG00000148926 ENSG00000130222 ENSG00000164400 ENSG00000107485 ENSG00000185591 ENSG00000179348 PMC9538505__F11 TRPV1 channel in spermatozoa is a molecular target for ROS-mediated sperm dysfunction and differentially expressed in both natural and ART pregnancy failure ENSG00000175793 ENSG00000117118 ENSG00000165280 ENSG00000120885 ENSG00000273686 ENSG00000163631 ENSG00000096063 ENSG00000074800 ENSG00000069849 ENSG00000167986 ENSG00000173436 ENSG00000099804 ENSG00000005381 ENSG00000130513 PMC6678087__F3 Representation of the two serrated pathways ENSG00000157764 ENSG00000170430 PMC7163052__F1 Oncolytic Virus-Mediated Targeting of the ERK Signaling Pathway Inhibits Invasive Propensity in Human Pancreatic Cancer PMC8456215__F1 Emerging Targets in Type 2 Diabetes and Diabetic Complications PMC6287696__F1 The mechanism by which Rel/NFKB-dependent STING expression activates antiviral autophagy to restrict ZIKV infection in fly brain ENSG00000162924 ENSG00000057663 PMC5676072__F1 Sirtuin roles in Hedgehog, Wnt/B‐catenin, and Notch stem cell signaling pathways ENSG00000183337 ENSG00000134982 ENSG00000168036 ENSG00000077463 ENSG00000096717 ENSG00000165617 ENSG00000283100 PMC5891173__F3 Aldo‐Keto reductase 1C2 (AKR1C2) expression in prostate cancer cell lines ENSG00000151632 ENSG00000203859 PMC8257776__F1 Molecular pathways of apoptosis and necroptosis ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 PMC4143352__F7 Tau Overexpression Impacts a Neuroinflammation Gene Expression Network Perturbed in Alzheimer’s Disease ENSG00000166340 ENSG00000123338 ENSG00000051523 ENSG00000168329 ENSG00000064601 ENSG00000011600 ENSG00000291920 ENSG00000120913 ENSG00000236625 ENSG00000145623 ENSG00000104863 ENSG00000221946 ENSG00000140678 ENSG00000101160 ENSG00000081237 ENSG00000140968 ENSG00000173786 ENSG00000129226 ENSG00000102931 ENSG00000134287 ENSG00000131095 ENSG00000273686 ENSG00000168610 ENSG00000159189 ENSG00000281614 ENSG00000115956 ENSG00000169220 ENSG00000173372 ENSG00000198435 ENSG00000149809 ENSG00000177606 ENSG00000163131 ENSG00000185668 ENSG00000112149 ENSG00000120594 PMC11951496__F1 Double role of IL-6 in the pathogenesis of atherosclerosis ENSG00000162711 ENSG00000172936 ENSG00000136869 PMC4264188__F2 BMP signaling pathway ENSG00000170365 ENSG00000125968 PMC4143352__F5 Tau Overexpression Impacts a Neuroinflammation Gene Expression Network Perturbed in Alzheimer’s Disease ENSG00000039537 ENSG00000140678 ENSG00000113600 ENSG00000203710 ENSG00000244731 ENSG00000117322 ENSG00000182326 ENSG00000236625 PMC6876322__F4 Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway analysis of the target genes of CTD-2357A8.3 in HNSCC tissues ENSG00000274211 ENSG00000154764 ENSG00000149212 ENSG00000157985 ENSG00000138079 ENSG00000139567 ENSG00000153037 ENSG00000188064 ENSG00000159388 ENSG00000157193 ENSG00000181894 ENSG00000072274 ENSG00000143401 ENSG00000265972 ENSG00000064300 ENSG00000292210 ENSG00000070444 ENSG00000173480 ENSG00000130164 ENSG00000008196 ENSG00000102098 ENSG00000182141 ENSG00000135503 ENSG00000160908 ENSG00000196233 ENSG00000282899 ENSG00000125637 ENSG00000143570 ENSG00000143549 ENSG00000163126 ENSG00000122122 ENSG00000122574 ENSG00000162924 ENSG00000173517 ENSG00000168610 ENSG00000074219 ENSG00000137509 ENSG00000196411 ENSG00000161791 ENSG00000120899 ENSG00000130382 ENSG00000147601 PMC1761701__F10 Proposed model of lacritin mitogenic signaling pathway lacritin signaling suggested by data outlined in the text ENSG00000115884 ENSG00000167323 ENSG00000198793 ENSG00000135413 ENSG00000198670 PMC8335813__F6 HHLA2 deficiency inhibits non‐small cell lung cancer progression and THP‐1 macrophage M2 polarization ENSG00000177575 ENSG00000087245 ENSG00000114455 ENSG00000135446 ENSG00000170558 ENSG00000123374 ENSG00000105810 ENSG00000100985 ENSG00000146648 PMC3787301__F4 The physiological and metabolic landscape of Melainabacteria ENSG00000144063 ENSG00000110711 ENSG00000122966 PMC7736543__F2 Reciprocal signaling between the capsule and cortex coordinately regulates SHH and Wnt pathway activation ENSG00000162552 ENSG00000183579 ENSG00000168036 ENSG00000164690 ENSG00000128602 ENSG00000146374 PMC7736543__F1 Adrenal cortex employs multiple cell populations with stem cell function to support cellular renewal ENSG00000179142 ENSG00000164690 PMC2736203__F2 Impact of a mixed microbial challenge on cell cycle control in HIGK ENSG00000149311 ENSG00000175054 ENSG00000132646 PMC3759014__F1 The main constituents of the Sonic Hedgehog (SHH) pathway include the SHH ligand and the transmembrane proteins PTCH1 and SMO ENSG00000164690 ENSG00000128602 PMC4832107__F2 Genome-wide gene expression analysis for S49 (Neo) and S49 (OS 4–25) cells ENSG00000084774 PMC7115196__F6 Pathway network associated with PCOS ENSG00000138207 ENSG00000118785 ENSG00000181104 ENSG00000113302 PMC11039994__F8 Levels of p53 govern the hierarchy of DNA damage tolerance pathway usage ENSG00000101751 ENSG00000186472 ENSG00000132646 ENSG00000164306 ENSG00000130997 ENSG00000121988 ENSG00000166169 PMC8621344__F2 Mitochondrial Dysfunction in Cancer Cachexia: Impact on Muscle Health and Regeneration ENSG00000009709 ENSG00000084093 PMC8141177__F1 LINC00261: a burgeoning long noncoding RNA related to cancer ENSG00000134982 ENSG00000168036 PMC3237867__F1 Metabolic pathways, transport, and receptors of S1P ENSG00000163914 ENSG00000183018 PMC11997273__F2 The vagus afferent nerve conveying gastric-derived ghrelin signals ENSG00000198576 ENSG00000121853 PMC2832309__F2 WWOX gene and gene product: tumor suppression through specific protein interactions ENSG00000019991 ENSG00000134982 ENSG00000177606 ENSG00000178568 PMC9598866__F5 Metabolite Profiling of Paraquat Tolerant Arabidopsis thaliana Radical-induced Cell Death1 (rcd1)—A Mediator of Antioxidant Defence Mechanisms ENSG00000069482 ENSG00000197429 ENSG00000115419 PMC4182081__F3 Regulation of TCF7 and HSP90AA1 by hsa-miR-185-5p in a prostate cancer pathway ENSG00000171791 PMC4182081__F2 Regulation of YWHAG, YWHAB, and PCNA by hsa-miR-185-5p in a cell cycle pathway ENSG00000144063 PMC2530034__F1 Transcriptional regulation and the pathway of RNA polymerase II transcription ENSG00000136807 ENSG00000101751 ENSG00000277273 ENSG00000166169 PMC2491640__F5 Regulatory network of important genes involved in EBV-dependent NPC ENSG00000165556 ENSG00000178035 ENSG00000142227 ENSG00000078399 ENSG00000116717 ENSG00000197442 ENSG00000010278 ENSG00000105639 ENSG00000146733 ENSG00000168610 ENSG00000124762 ENSG00000123374 ENSG00000185591 ENSG00000100985 ENSG00000124795 ENSG00000146648 ENSG00000143995 PMC2600469__F4 Genes regulated by SHP in PPAR signaling pathway ENSG00000135218 ENSG00000099194 PMC4182081__F4 Regulation of TCF7 by hsa-miR-20b-5p and hsa-miR-17-5p in a thyroid cancer pathway ENSG00000047410 ENSG00000157764 ENSG00000136997 ENSG00000168036 PMC4349157__F1 Sphingolipid metabolic network ENSG00000178814 ENSG00000198670 ENSG00000023909 PMC3889683__F3 Schematic presentation of potential signaling network of HER2-NFKB-PI3 K-Akt-STAT3 ENSG00000163629 ENSG00000168610 ENSG00000139687 PMC11280308__F3 Mechanisms of action of the A ENSG00000070831 ENSG00000115415 ENSG00000102871 ENSG00000135446 ENSG00000170558 ENSG00000198793 ENSG00000137265 ENSG00000123374 ENSG00000120868 ENSG00000168040 ENSG00000168610 PMC6128084__F6 Cellular metabolism for heme synthesis during early and late erythropoiesis ENSG00000177542 ENSG00000144659 ENSG00000158578 PMC6522942__F1 Cell surface and endosomal signaling pathway of TLRs ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000177606 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC6678403__F3 Negative role of AMPK in angiogenesis ENSG00000170365 ENSG00000198793 ENSG00000114315 PMC6522942__F3 Polyphenols modulating upstream (TLR activation) and downstream (different kinase and transcription factors) pathway of surface and endogenous TLR to reduce or demolish pro-inflammatory cytokines and type I interferon generation ENSG00000172936 ENSG00000150455 ENSG00000175104 PMC6522942__F2 TLRs-signaling in microglial cells in different neurodegenerative disease progression ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000128268 PMC6678403__F1 Regulation of sprouting angiogenesis ENSG00000128917 ENSG00000114315 PMC4898593__F5 Signal transduction from G-protein-coupled receptors and integrins ENSG00000070831 ENSG00000291971 ENSG00000197943 PMC1386711__F4 MAPK signaling pathway mapping ENSG00000070831 ENSG00000188404 ENSG00000197601 PMC6721652__F1 Canonical WNT pathway in on and off states ENSG00000281324 ENSG00000134982 ENSG00000168036 PMC9240865__F3 Membrane-bound O-acyltransferase 7 (MBOAT7)-driven phosphatidylinositol remodeling in advanced liver disease ENSG00000198670 ENSG00000273592 PMC6721652__F4 Drugs developed against canonical WNT pathway components ENSG00000281324 ENSG00000134982 ENSG00000167941 ENSG00000102312 ENSG00000168036 ENSG00000173273 PMC9240865__F2 Membrane-bound O-acyltransferase 7 (MBOAT7)-driven phosphatidylinositol remodeling in advanced liver disease ENSG00000173599 ENSG00000198670 ENSG00000273592 PMC6182840__F1 The sorting mechanism of exosomal miRNA MiRNA genes are transcribed into primary miRNAs (pri-miRNA) by Pol-II ENSG00000113360 ENSG00000123908 PMC6721652__F3 Canonical WNT pathway components associated with disease ENSG00000281324 ENSG00000134982 ENSG00000168036 PMC8393842__F1 Adding Some “Splice” to Stress Eating: Autophagy, ESCRT and Alternative Splicing Orchestrate the Cellular Stress Response ENSG00000177169 ENSG00000152348 ENSG00000198793 ENSG00000074319 ENSG00000057663 ENSG00000101421 PMC4217539__F6 Human pre-BCR-induced signal transduction depicted from the current study ENSG00000166349 ENSG00000291603 ENSG00000196092 PMC8983055__F3 Proteomic and Phosphoproteomic Changes of MAPK-Related Inflammatory Response in an Animal Model of Neuropathic Pain by Differential Target Multiplexed SCS and Low-Rate SCS ENSG00000242689 ENSG00000156709 ENSG00000000971 ENSG00000129351 ENSG00000132693 ENSG00000168610 ENSG00000229314 ENSG00000164104 ENSG00000137642 ENSG00000133048 ENSG00000122756 ENSG00000145192 ENSG00000175899 ENSG00000189403 ENSG00000136869 ENSG00000062485 PMC6716664__F3 MicroRNA regulation in colorectal cancer tissue and serum ENSG00000049323 ENSG00000121989 ENSG00000111537 ENSG00000005339 ENSG00000095739 ENSG00000156574 ENSG00000134363 ENSG00000164093 PMC6716664__F2 MicroRNA regulation in colorectal cancer tissue and serum ENSG00000149311 ENSG00000087095 ENSG00000171105 ENSG00000157764 ENSG00000198517 ENSG00000127528 ENSG00000123374 ENSG00000162924 PMC9223523__F3 Mutations of GCOP Gene Disturb Drosophila melanogaster Innate Immune Response to Pseudomonas aeruginosa ENSG00000177030 ENSG00000166402 ENSG00000172936 ENSG00000175104 PMC3951797__F6 Postsqualene cholesterol biosynthetic pathway ENSG00000116133 ENSG00000172893 ENSG00000109929 PMC9223523__F5 Mutations of GCOP Gene Disturb Drosophila melanogaster Innate Immune Response to Pseudomonas aeruginosa ENSG00000166402 ENSG00000172936 ENSG00000162924 ENSG00000083799 ENSG00000168040 PMC9223523__F4 Mutations of GCOP Gene Disturb Drosophila melanogaster Innate Immune Response to Pseudomonas aeruginosa ENSG00000281766 ENSG00000162924 ENSG00000083799 ENSG00000168040 ENSG00000143196 ENSG00000175104 ENSG00000084774 PMC3428657__F1 The signaling pathway ofGHRregulated by let-7b ENSG00000112964 ENSG00000169047 PMC7643606__F2 Leishmania spp.-induced activation of the NLRP3 inflammasome ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC7643606__F1 NLRP3 inflammasome ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC7827203__F3 Crosstalk of MDSC and Treg ENSG00000089692 ENSG00000168610 PMC4250176__F6 MYC Is an Early Response Regulator of Human Adipogenesis in Adipose Stem Cells PMC7665128__F2 Calcium homeostasis and signaling in healthy neurons ENSG00000167323 ENSG00000293604 ENSG00000156026 PMC6499991__F6 Proposed model of participation of SNHG1 in the regulation of signaling pathways that contribute sorafenib resistance in HCC cells ENSG00000168003 ENSG00000198793 PMC7948403__F5 Ferroptosis in Alzheimer's disease ENSG00000205221 ENSG00000167468 PMC5485509__F2 Histone modifications regulate gene transcription involving renal fibrosis of diabetic kidney disease ENSG00000196363 PMC5945880__F1 Interferon-gamma (IFNG) canonical signaling pathway ENSG00000115415 ENSG00000125347 PMC10896652__F1 Relationship between NGF/TrKA signaling pathway and KOA peripheral hyperalgesia ENSG00000184207 ENSG00000196689 PMC2789789__F6 Scheme of the biosynthesis pathways for PC, PE, and PS in human P ENSG00000173599 PMC5769535__F1 Neurotransmitters signalling pathways in cancer ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC10869479__F3 P2X7-mediated signaling pathway ENSG00000162711 ENSG00000142192 ENSG00000125538 PMC11646805__F2 Diagram of endothelial cell mutant GAq signaling (p ENSG00000198793 PMC5746412__F5 PKM2 in carcinogenesis and oncotherapy ENSG00000198793 ENSG00000104228 ENSG00000146648 PMC6774422__F2 LRRK2 substrates involved in vesicle trafficking and synaptic transmission ENSG00000169228 ENSG00000172780 ENSG00000084733 ENSG00000099246 ENSG00000206418 ENSG00000111737 PMC8836911__F1 Theranostic Interpolation of Genomic Instability in Breast Cancer ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000051180 ENSG00000105810 ENSG00000139618 PMC6543238__F1 Tumor immunity by radiotherapy and immune checkpoint blockade ENSG00000164430 ENSG00000134982 PMC4077896__F1 Autophagic structures in the regulation of MAPK phosphorylation ENSG00000138798 PMC8927079__F2 Aryl Hydrocarbon Receptor in the Pathogenesis of Environmentally-Induced Squamous Cell Carcinomas of the Skin ENSG00000171759 ENSG00000140465 ENSG00000106546 PMC8927079__F1 Aryl Hydrocarbon Receptor in the Pathogenesis of Environmentally-Induced Squamous Cell Carcinomas of the Skin ENSG00000140465 ENSG00000146648 ENSG00000106546 PMC8102695__F1 Use of the Anticoagulant Heparin and Corticosteroid Dexamethasone as Prominent Treatments for COVID-19 ENSG00000003436 ENSG00000006712 ENSG00000134982 ENSG00000130234 PMC3527701__F2 Mammalian N-end rule pathway.,,, N-terminal residues are indicated by single-letter abbreviations for amino acids ENSG00000156795 ENSG00000157045 ENSG00000127481 ENSG00000104517 ENSG00000159459 ENSG00000107669 PMC6115613__F5 Summary of the signaling pathways involved in cell migration and invasion through p75NTR ENSG00000087245 ENSG00000138795 ENSG00000291971 ENSG00000168036 ENSG00000168610 ENSG00000196628 ENSG00000038382 ENSG00000156299 ENSG00000122691 ENSG00000143761 ENSG00000177606 ENSG00000100985 ENSG00000134313 PMC3043160__F4 Calcium-mediated mechanisms of cystic expansion ENSG00000163914 ENSG00000168036 PMC6115613__F4 In some cases, migration and invasion are stimulated through NGF or proNGF upon activation of p75NTR and TrkA ENSG00000087245 ENSG00000138795 ENSG00000122691 ENSG00000291971 ENSG00000177606 ENSG00000168036 ENSG00000100985 ENSG00000196628 ENSG00000134313 PMC6115613__F3 p75NTR and TrkB pathways ENSG00000038382 ENSG00000087245 ENSG00000156299 ENSG00000122691 ENSG00000143761 ENSG00000177606 ENSG00000100985 ENSG00000168610 ENSG00000134313 PMC8421567__F1 Emerging Role of T-Cell Immunoglobulin Mucin-3 in Breast Cancer: A Promising Target For Immunotherapy ENSG00000168036 ENSG00000168610 PMC4485494__F3 Glycogen Synthase Kinase-3 in Insulin and Wnt Signalling : a Double-edged Sword? ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5777890__F7 Reactive Oxygen Species Damage Drives Cardiac and Mitochondrial Dysfunction Following Acute Nano-Titanium Dioxide Inhalation Exposure ENSG00000151726 ENSG00000073578 ENSG00000130414 ENSG00000138029 ENSG00000184983 ENSG00000129450 ENSG00000254445 ENSG00000150093 ENSG00000163541 ENSG00000105953 ENSG00000010256 ENSG00000165264 ENSG00000139180 ENSG00000150991 ENSG00000164405 ENSG00000213619 ENSG00000065518 ENSG00000100412 ENSG00000132535 ENSG00000128928 PMC7599585__F3 Distinct mechanisms leading to Nrf2 activation in cancer cells ENSG00000167363 ENSG00000121060 ENSG00000079999 PMC4074489__F4 p58IPK and UPR-associated inflammatory signaling pathways ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC7139386__F1 Defects in Galactose Metabolism and Glycoconjugate Biosynthesis in a UDP-Glucose Pyrophosphorylase-Deficient Cell Line Are Reversed by Adding Galactose to the Growth Medium ENSG00000109814 ENSG00000069482 PMC6276109__F1 Breast Cancer Stem Cells: We’ve got them surrounded ENSG00000186810 ENSG00000291971 ENSG00000173039 ENSG00000083799 ENSG00000168610 ENSG00000146648 PMC7783806__F8 Pathway signalling network generated from the 1000 most differentially methylated genes ENSG00000090061 ENSG00000162337 ENSG00000102871 ENSG00000291971 ENSG00000166484 ENSG00000049768 ENSG00000142082 ENSG00000166851 ENSG00000196396 ENSG00000122025 ENSG00000186847 ENSG00000171456 ENSG00000084676 ENSG00000104783 ENSG00000166501 ENSG00000196498 ENSG00000182580 ENSG00000184304 ENSG00000064835 ENSG00000154928 ENSG00000122180 ENSG00000112964 ENSG00000109320 ENSG00000109321 ENSG00000291431 ENSG00000137070 ENSG00000065559 ENSG00000090776 ENSG00000100815 ENSG00000285456 ENSG00000183395 ENSG00000198740 ENSG00000124216 ENSG00000129993 ENSG00000143514 ENSG00000186716 ENSG00000070770 ENSG00000185532 ENSG00000104290 ENSG00000165409 ENSG00000146648 ENSG00000128285 ENSG00000164086 PMC4091760__F2 Regulatory crosstalk and interference between the xenobiotic and hypoxia sensing pathways at the AhR-ARNT-HIF1A signaling node ENSG00000106546 PMC7778818__F5 The HO in the present case PMC9138070__F1 Physical-Exercise-Induced Antioxidant Effects on the Brain and Skeletal Muscle ENSG00000228716 ENSG00000178573 ENSG00000079999 PMC2148057__F8 Proteosomal degradation pathway ENSG00000224320 ENSG00000069869 ENSG00000276051 ENSG00000068878 PMC9221178__F5 Microbial-Derived Toll-like Receptor Agonism in Cancer Treatment and Progression ENSG00000183735 ENSG00000136869 ENSG00000131323 ENSG00000164342 PMC9221178__F4 Microbial-Derived Toll-like Receptor Agonism in Cancer Treatment and Progression ENSG00000134982 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC2148057__F6 Sugar metabolism pathways in MCF-7 and ZR75-1 cells profiled by GenMAPP ENSG00000173599 ENSG00000113494 PMC9221178__F2 Microbial-Derived Toll-like Receptor Agonism in Cancer Treatment and Progression ENSG00000134982 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC2148057__F5 GenMAPP view of energy production pathway in MCF-7 and ZR75-1 cells ENSG00000160194 ENSG00000147684 ENSG00000073578 ENSG00000117118 ENSG00000138495 ENSG00000166260 ENSG00000175567 ENSG00000004779 ENSG00000178127 ENSG00000143252 ENSG00000183648 ENSG00000136521 ENSG00000151366 ENSG00000110717 ENSG00000119013 ENSG00000166211 PMC7366512__F1 Biomaterial-triggered complement activation drives early thromboinflammatory changes during hemodialysis ENSG00000125538 ENSG00000197405 ENSG00000166278 ENSG00000182326 PMC2775119__F3 Ciliary functions of cystoproteins: mechanosensation and cell cycle control ENSG00000135446 ENSG00000173599 ENSG00000123374 ENSG00000105810 PMC9627224__F1 RNASeq profiling of COVID19‐infected patients identified an EIF2AK2 inhibitor as a potent SARS‐CoV‐2 antiviral ENSG00000163435 ENSG00000239732 ENSG00000120690 ENSG00000177606 ENSG00000136869 ENSG00000125347 PMC4039002__F9 Aggregate-Prone R120GCRYAB Triggers Multifaceted Modifications of the Thioredoxin System ENSG00000171720 ENSG00000151929 PMC5224520__F7 Bridging topological and functional information in protein interaction networks by short loops profiling ENSG00000111581 ENSG00000104884 ENSG00000118007 ENSG00000134308 ENSG00000250254 ENSG00000112118 ENSG00000205250 ENSG00000073111 ENSG00000091651 ENSG00000198056 ENSG00000076003 ENSG00000093009 ENSG00000105325 ENSG00000116670 ENSG00000104320 ENSG00000176248 ENSG00000113558 ENSG00000136997 ENSG00000204843 ENSG00000139687 ENSG00000179041 ENSG00000100345 ENSG00000161888 ENSG00000117399 ENSG00000094804 ENSG00000198176 ENSG00000156970 ENSG00000006451 ENSG00000103769 ENSG00000127824 ENSG00000108344 ENSG00000173692 ENSG00000147082 ENSG00000105329 ENSG00000263042 ENSG00000135476 ENSG00000277273 ENSG00000164162 ENSG00000134480 ENSG00000172534 ENSG00000081377 ENSG00000132383 ENSG00000115942 ENSG00000130222 ENSG00000135336 ENSG00000162521 ENSG00000123374 ENSG00000112742 ENSG00000253729 ENSG00000005339 ENSG00000119541 ENSG00000108055 ENSG00000175793 ENSG00000145604 ENSG00000149311 ENSG00000122882 ENSG00000135446 ENSG00000164754 ENSG00000133119 ENSG00000095002 ENSG00000082212 ENSG00000256646 ENSG00000163636 ENSG00000080839 ENSG00000132341 PMC5173156__F6 Down-regulation of Krüppel-like factor-4 by microRNA-135a-5p promotes proliferation and metastasis in hepatocellular carcinoma by transforming growth factorB1 ENSG00000170558 ENSG00000136826 PMC4533315__F4 ESEA: Discovering the Dysregulated Pathways based on Edge Set Enrichment Analysis ENSG00000117020 ENSG00000181852 ENSG00000065361 ENSG00000158458 PMC3670293__F1 JAK-STAT pathway in hypertrophic stress signaling and genomic stress response ENSG00000128342 ENSG00000168610 PMC4533315__F3 ESEA: Discovering the Dysregulated Pathways based on Edge Set Enrichment Analysis ENSG00000132906 ENSG00000138795 ENSG00000002330 ENSG00000157764 ENSG00000134982 ENSG00000050748 ENSG00000168036 ENSG00000105647 ENSG00000171791 ENSG00000169032 ENSG00000121879 ENSG00000164305 ENSG00000117020 ENSG00000213658 ENSG00000169750 ENSG00000089685 ENSG00000177606 ENSG00000136997 ENSG00000171608 ENSG00000095002 PMC6528196__F3 Predicted metabolic pathway of lignocellulose-derived inhibitors ENSG00000100473 ENSG00000080823 PMC5963631__F5 Etoposide-induced DNA damage affects multiple cellular pathways in addition to DNA damage response ENSG00000280831 ENSG00000130741 ENSG00000274700 ENSG00000115268 ENSG00000164587 ENSG00000111361 ENSG00000142534 ENSG00000130811 ENSG00000138326 ENSG00000205609 ENSG00000145592 ENSG00000184110 ENSG00000144713 PMC6968989__F2 Genetic pathways effected by mutations in maxillofacial bone tumours ENSG00000157764 ENSG00000134982 ENSG00000168036 ENSG00000077782 ENSG00000087460 ENSG00000196712 PMC5883416__F2 Calcium in cell cycle G1/S transitioning via the MAPK pathway ENSG00000135446 ENSG00000139687 PMC2826554__F1 Beta-AR-dependent translation initiation ENSG00000198793 PMC6646053__F1 Antibody mediated complement activation ENSG00000203710 ENSG00000196352 ENSG00000117335 PMC3670293__F4 JAK-STAT pathway in hypertrophic stress signaling and genomic stress response ENSG00000136807 ENSG00000167074 ENSG00000128342 ENSG00000168610 PMC6320836__F6 Status of proteins that participate in the autophagy pathway in glioblastoma ENSG00000177169 ENSG00000198382 ENSG00000284099 ENSG00000168036 ENSG00000146648 ENSG00000057663 PMC7722191__F1 Action of novel therapies in ET and PV ENSG00000117400 PMC3319453__F2 Insulin, IGF-I and IGF-II binding to IR and IGF-IR ENSG00000284774 ENSG00000002330 ENSG00000198793 ENSG00000169047 ENSG00000026103 PMC9414313__F2 Exosomes: Small Vesicles with Important Roles in the Development, Metastasis and Treatment of Breast Cancer ENSG00000148400 ENSG00000050165 ENSG00000168036 ENSG00000133961 ENSG00000168610 PMC2931413__F1 Hermaphroditism in Caenorhabditis nematodes.(A) The Caenorhabditis hermaphrodite gonad ENSG00000115884 ENSG00000162512 ENSG00000169439 PMC4831703__F1 The isoprenoid biosynthetic pathway (IBP, ) provides critical substrates for posttranslational modification of proteins that modulate cell signaling and regulatory processes ENSG00000160752 ENSG00000197429 PMC4520528__F2 B cell-derived cytokines direct the ensuing immune response ENSG00000226275 PMC7073546__F4 Synthesis of capsaicinoids adapted from Mazourek et al ENSG00000145020 ENSG00000062485 PMC4916380__F3 Central metabolic pathway in C. tyrobutyricum ENSG00000261701 ENSG00000164597 ENSG00000150787 PMC7290354__F5 PI3K/Akt pathway can be activated in different ways, as for example by G-protein coupled receptors (GPCRs), integrin or cytokine receptors and it represents a mediator between ECM and fibroblasts’ cell cycle ENSG00000002330 ENSG00000198793 PMC11674331__F5 PAK1 and PAK2 in angiogenesis ENSG00000149269 PMC11674331__F4 PAK1 and PAK2 in vascular remodeling ENSG00000002330 ENSG00000149269 PMC8456215__F8 Emerging Targets in Type 2 Diabetes and Diabetic Complications ENSG00000148400 ENSG00000291971 ENSG00000074181 ENSG00000187764 PMC9163835__F4 Quercetin Can Improve Spinal Cord Injury by Regulating the mTOR Signaling Pathway ENSG00000112561 ENSG00000189403 ENSG00000136869 ENSG00000171791 PMC7456540__F8 Working hypotheses of two opposing mechanisms that concomitantly drive and silence nerve injury-induced latent sensitization ENSG00000104321 ENSG00000196689 PMC9163835__F3 Quercetin Can Improve Spinal Cord Injury by Regulating the mTOR Signaling Pathway ENSG00000154342 ENSG00000171791 PMC3153965__F7 Network representation of altered cellular functions during colonization of the mouse colon by A ENSG00000180210 ENSG00000135218 ENSG00000197471 ENSG00000213402 ENSG00000113520 ENSG00000117335 ENSG00000110876 PMC6562438__F1 Schematic overview of pathways that are involved in desmoplasia in pancreatic cancer, including drugs and their targets ENSG00000165197 ENSG00000198793 ENSG00000026508 ENSG00000112715 ENSG00000128602 ENSG00000150630 PMC9163835__F2 Quercetin Can Improve Spinal Cord Injury by Regulating the mTOR Signaling Pathway ENSG00000198793 ENSG00000112561 ENSG00000189403 ENSG00000136869 ENSG00000168610 PMC9163835__F1 Quercetin Can Improve Spinal Cord Injury by Regulating the mTOR Signaling Pathway ENSG00000162711 ENSG00000181019 ENSG00000198793 PMC11674331__F6 PAK1 and PAK2 in the regulation of vascular integrity and permeability ENSG00000070831 ENSG00000149269 PMC6117929__F8 TGFB1 and E2 cause differential regulation of genes involved in extracellular matrix turnover ENSG00000100234 ENSG00000087245 ENSG00000186340 ENSG00000157150 ENSG00000197635 ENSG00000157227 ENSG00000175899 ENSG00000100985 ENSG00000078098 ENSG00000105825 PMC8228183__F17 NADPH Oxidases (NOX): An Overview from Discovery, Molecular Mechanisms to Physiology and Pathology ENSG00000105329 ENSG00000086991 PMC12217801__F6 Proposed molecular mechanism by which PBM preserves erectile function in diabetic mice PMC7081179__F1 7Alpha-Hydroxylase and (25R)26-hydroxylase pathways of oxysterol biosynthesis ENSG00000198610 ENSG00000180432 ENSG00000099377 ENSG00000122787 ENSG00000135929 PMC9300166__F1 Mismatch repair and clinical response to immune checkpoint inhibitors in endometrial cancer ENSG00000177084 ENSG00000095002 ENSG00000122512 PMC8228183__F20 NADPH Oxidases (NOX): An Overview from Discovery, Molecular Mechanisms to Physiology and Pathology ENSG00000137857 ENSG00000140279 ENSG00000086991 ENSG00000074771 PMC3203699__F8 TRAF3-mediated positive and negative regulation of IFN signaling ENSG00000088888 ENSG00000131323 ENSG00000276561 PMC4115241__F5 Schematic drawing showed activated HFSCs contributed to SN development ENSG00000125398 ENSG00000168036 ENSG00000174059 PMC5014091__F1 Wnt/Beta-catenin upregulation in CRC and PDAC ENSG00000004975 ENSG00000134982 ENSG00000168036 ENSG00000196562 PMC6200703__F2 Regulatory effects of lncRNAs and miRNAs on autophagy in malignant tumorigenesis ENSG00000011304 ENSG00000198793 ENSG00000144848 ENSG00000189403 ENSG00000145782 ENSG00000168610 ENSG00000136874 PMC8411705__F2 Neutrophils in Glioma and Brain Metastases ENSG00000108691 ENSG00000101751 ENSG00000239732 ENSG00000111537 ENSG00000189403 ENSG00000169429 ENSG00000100985 ENSG00000112715 PMC6635658__F7 Schematic model depicting the possible mechanisms of nobiletin-mediated inhibition of renal cancer cell proliferation ENSG00000291971 ENSG00000168610 PMC9396497__F1 MicroRNA-based targeting of the Rho/ROCK pathway in therapeutic strategies after spinal cord injury ENSG00000141867 ENSG00000169783 ENSG00000075213 PMC7789600__F2 Roles of lipoproteins in the exogenous, endogenous, and reverse cholesterol pathways ENSG00000042832 PMC9010872__F1 O-GlcNAcylation and Its Role in Cancer-Associated Inflammation ENSG00000147162 ENSG00000198380 ENSG00000198408 ENSG00000013375 PMC3181220__F3 Novel treatment strategies for patients with relapsed classical Hodgkin lymphoma PMC4730267__F2 Gene members (green rectangle) in the PPAR signaling pathway that are regulated by maternal high fructose in the male offspring kidney at one day of age (red stars) ENSG00000115266 ENSG00000100979 PMC186370__F1 Spot 42 RNA mediates discoordinate expression of the E. coli galactose operon ENSG00000069482 ENSG00000132693 PMC1766780__F2 Cytokine signalling and the pathogenesis of severe combined immunodeficiency (SCID) ENSG00000145839 ENSG00000164136 ENSG00000113520 ENSG00000104432 PMC4817799__F4 Regulation of neural precursor plasticity within the classical neurogenic zones ENSG00000134982 ENSG00000138798 ENSG00000145321 ENSG00000096088 ENSG00000164690 ENSG00000139352 PMC10921668__F8 The early ATL80-dependent response to WDS and its presumed function in retrograde signaling pathways ENSG00000105722 ENSG00000171735 PMC8228183__F22 NADPH Oxidases (NOX): An Overview from Discovery, Molecular Mechanisms to Physiology and Pathology ENSG00000087245 ENSG00000149269 ENSG00000086991 ENSG00000113520 ENSG00000168610 PMC3666312__F1 Current landscape for T-cell targeting in autoimmunity and transplantation ENSG00000134982 ENSG00000198793 PMC8438230__F3 Glioma Stem-Like Cells and Metabolism: Potential for Novel Therapeutic Strategies ENSG00000173599 ENSG00000115419 ENSG00000159399 ENSG00000167701 PMC7170819__F2 Angiogenic factors and receptors involved in GBM angiogenesis ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC8565990__F1 BTK Inhibition in the Treatment of Chronic Lymphocytic Leukemia: A Clinical View ENSG00000177455 ENSG00000095585 ENSG00000105369 ENSG00000007312 ENSG00000198793 ENSG00000197943 ENSG00000010671 PMC5203884__F1 p53 suppresses the cell proliferation mediated by the Rb-E2F pathway ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC8640807__F2 Recent advances of SIRT1 and implications in chemotherapeutics resistance in cancer ENSG00000143799 ENSG00000103222 ENSG00000096717 PMC7517653__F6 SFR changed substrate metabolism in ruminal epithelium ENSG00000130957 ENSG00000116133 ENSG00000019186 ENSG00000291748 ENSG00000108821 ENSG00000159399 PMC6305196__F9 Model for the CK-dependent photomorphogenic response in etiolated Arabidopsis seedlings ENSG00000140543 PMC2975941__F2 Classical and non-canonical NFKB pathways ENSG00000104856 ENSG00000186716 ENSG00000111321 ENSG00000131323 PMC9038780__F10 Putative synergistic effects of MGO and aSyn in the midbrain ENSG00000154059 PMC10931770__F2 Positive and negative regulation of osteoclast differentiation ENSG00000107562 ENSG00000128272 ENSG00000196092 ENSG00000140044 ENSG00000175104 ENSG00000131196 PMC4312878__F1 Transcription of Inflammatory Genes: Long Noncoding RNA and Beyond ENSG00000140968 ENSG00000136869 ENSG00000162772 PMC8656574__F2 Long Non-Coding RNA (lncRNA) in Oral Squamous Cell Carcinoma: Biological Function and Clinical Application ENSG00000170961 ENSG00000170558 ENSG00000026508 ENSG00000266524 PMC1446957__F5 In vitro keratinocyte mitosis ENSG00000169291 ENSG00000138798 ENSG00000146648 PMC8656574__F1 Long Non-Coding RNA (lncRNA) in Oral Squamous Cell Carcinoma: Biological Function and Clinical Application ENSG00000245848 ENSG00000171791 ENSG00000131023 PMC9304887__F1 Small Interfering RNA for Gliomas Treatment: Overcoming Hurdles in Delivery ENSG00000136997 ENSG00000168610 ENSG00000146648 ENSG00000123908 PMC6409899__F1 Models of replication-coupled ICL repair ENSG00000144554 ENSG00000188827 ENSG00000187790 ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000166508 PMC6437054__F1 Interaction map and annotation enrichment of the newly synthesized mazEF-related proteins ENSG00000166855 ENSG00000163914 PMC6409899__F3 The Fanconi anemia pathway suppresses R-loop-associated genome instability ENSG00000012048 ENSG00000107290 ENSG00000144554 ENSG00000187790 PMC8009801__F3 Identification of small molecules targeting the Hippo-TAZ/YAP pathway ENSG00000109321 ENSG00000136997 ENSG00000131023 PMC9108399__F2 Emerging Portrait of Glial Cell Line-derived Neurotrophic Factor Family Receptor Alpha (GFRA) in Cancers ENSG00000124216 ENSG00000291971 ENSG00000198793 ENSG00000136826 ENSG00000117407 PMC9108399__F1 Emerging Portrait of Glial Cell Line-derived Neurotrophic Factor Family Receptor Alpha (GFRA) in Cancers ENSG00000168546 ENSG00000146013 ENSG00000125861 ENSG00000171119 ENSG00000117407 ENSG00000125650 PMC7532108__F7 Proposed pathway of recovery of R28 cells, induced by hPMSC-derived exosomes, after hypoxic damage ENSG00000168036 ENSG00000126261 PMC8781453__SF1 Downregulation of the LncRNA MEG3 Promotes Osteogenic Differentiation of BMSCs and Bone Repairing by Activating Wnt/Beta-Catenin Signaling Pathway ENSG00000168036 PMC2720607__F2 Principal enzymes and substrates of the folate pathway involved in formation of tetrahydrofolate (THF) and its utilisation in the thymidylate cycle ENSG00000228716 ENSG00000095059 ENSG00000136877 PMC4218690__F1 Honokiol and ionizing radiation (IR) affect Notch signaling ENSG00000136997 PMC3605582__F1 Key mediators of innate and adaptive immunity, development, and signalling ENSG00000110944 ENSG00000174125 ENSG00000244731 ENSG00000166278 ENSG00000168811 ENSG00000168610 ENSG00000276561 ENSG00000162594 ENSG00000096996 ENSG00000138378 ENSG00000226275 ENSG00000239732 ENSG00000224320 ENSG00000105397 ENSG00000187554 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000113302 ENSG00000184216 ENSG00000164342 PMC3631253__F4 A Protein Prioritization Approach Tailored for the FA/BRCA Pathway ENSG00000066923 ENSG00000184445 ENSG00000100206 ENSG00000054796 ENSG00000138160 ENSG00000198901 ENSG00000151503 ENSG00000122952 ENSG00000165478 ENSG00000115942 ENSG00000126001 ENSG00000172201 ENSG00000072609 PMC2574638__F8 Complement C3 and C4 expression in C1q sufficient and deficient mouse models of Alzheimer’s Disease ENSG00000142192 ENSG00000002330 PMC4312878__F3 Transcription of Inflammatory Genes: Long Noncoding RNA and Beyond ENSG00000150782 ENSG00000168610 ENSG00000197451 PMC10748332__F5 Signaling pathways involved in neuroprotective mechanisms ENSG00000198793 ENSG00000138777 PMC9178153__F2 Autophagy in muscle regeneration: potential therapies for myopathies ENSG00000009709 ENSG00000177169 ENSG00000122180 ENSG00000158828 ENSG00000112561 ENSG00000096717 ENSG00000057663 PMC4838159__F1 Five significant subnetworks of the N-group, associated with (A) glutathione metabolism (B) leucine and isoleucine metabolism (C) pancreatic cancer (D) calcium signaling pathway and (E) the mitogen-activated protein kinase pathway ENSG00000170899 ENSG00000109320 ENSG00000008394 ENSG00000143933 ENSG00000069956 ENSG00000112715 ENSG00000168610 ENSG00000127884 ENSG00000211445 ENSG00000177189 ENSG00000117862 ENSG00000085871 ENSG00000117305 PMC10506243__F5 Protein-protein interaction network and functional enrichment analysis of proteins with acetylation, carbamylation and phosphorylation sites regulated by bacterial lipopolysaccharide (LPS) ENSG00000182718 ENSG00000160789 ENSG00000099901 ENSG00000178035 ENSG00000163902 ENSG00000153201 ENSG00000100345 ENSG00000108654 ENSG00000092199 ENSG00000161960 ENSG00000009954 ENSG00000101557 ENSG00000074800 ENSG00000167986 ENSG00000130402 ENSG00000055609 ENSG00000146701 PMC4729166__F2 Schematic illustration of the molecular processes leading to apoptosis in renal proximal tubular epithelial cells ENSG00000172936 ENSG00000168040 ENSG00000026103 PMC4729166__F1 The activation of the NFKB transcription factor pathway by liposaccharide (LPS), TNFA, high mobility group (HMG)B1, and polymicrobial sepsis ENSG00000170458 ENSG00000189403 ENSG00000172936 ENSG00000175104 PMC8773516__F2 Pathophysiology and Therapeutics of Thoracic Aortic Aneurysm in Marfan Syndrome PMC6004386__F1 Binding of S100A8/A9 to toll-like receptor (TLR) 4 triggers the MyD88-dependent pathway, appearing to play a vital role in inflammation ENSG00000143546 ENSG00000163220 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC9525711__F7 Schematic depicting the role of TLB on AD ENSG00000172936 ENSG00000136869 ENSG00000142082 ENSG00000175104 PMC11856057__F2 Signal transduction in the Hedgehog (Hh) signaling pathway ENSG00000180447 ENSG00000106571 ENSG00000144857 ENSG00000166813 ENSG00000154309 ENSG00000128602 PMC11856057__F1 General mechanisms involved in Notch signaling ENSG00000283780 ENSG00000184384 ENSG00000196782 ENSG00000114315 ENSG00000137845 PMC9200284__F2 Adenosine Kinase on Deoxyribonucleic Acid Methylation: Adenosine Receptor-Independent Pathway in Cancer Therapy ENSG00000196839 PMC9200284__F1 Adenosine Kinase on Deoxyribonucleic Acid Methylation: Adenosine Receptor-Independent Pathway in Cancer Therapy ENSG00000088305 ENSG00000139372 PMC9236768__F7 Jiawei Yanghe Decoction Regulates Bone-Lipid Balance through the BMP-SMAD Signaling Pathway to Promote Osteogenic Differentiation of Bone Mesenchymal Stem Cells ENSG00000170365 PMC8246373__F2 Activity-Dependent Gene Expression in Neurons ENSG00000173599 ENSG00000127948 PMC1383515__F6 Proposed tentative mechanism underlying MAFA-mediated selective inhibition of FcɛRI-induced cytokine gene transcription ENSG00000010810 ENSG00000177606 PMC6928935__F1 The phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) pathway ENSG00000102034 ENSG00000198793 ENSG00000155792 ENSG00000164327 PMC9123899__F2 Interfering with interferons: targeting the JAK-STAT pathway in complications of systemic juvenile idiopathic arthritis (SJIA) ENSG00000111537 ENSG00000115590 ENSG00000125538 ENSG00000168610 PMC6218675__F1 Nuclear envelope proteins and their potential roles in EDMD physiopathology ENSG00000143815 PMC9123899__F1 Interfering with interferons: targeting the JAK-STAT pathway in complications of systemic juvenile idiopathic arthritis (SJIA) ENSG00000159128 ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000185436 ENSG00000027697 ENSG00000243646 ENSG00000142166 PMC7270498__F2 ncRNAs Regulate Cell Death Pathways to Influence HCC ChemoresistanceMultiple miRNAs and lncRNAs act as mediators of the autophagic process in HCC cells by regulating the PI3K/Akt signaling pathway ENSG00000177169 ENSG00000198793 ENSG00000164938 ENSG00000168040 ENSG00000145782 ENSG00000057663 ENSG00000026103 PMC7270498__F1 ncRNAs Affect Drug Efflux and Nrf2-Dependent Drug Metabolism in HCC CellsVarious miRNAs and lncRNAs can regulate intracellular drug concentrations in HCC cells by targeting drug efflux pumps ENSG00000228716 ENSG00000105656 ENSG00000140443 ENSG00000079999 PMC8583788__F2 Disentangling Mitochondria in Alzheimer’s Disease ENSG00000119912 ENSG00000096717 ENSG00000142082 ENSG00000106459 PMC8710681__F3 Mitotic and DNA Damage Response Proteins: Maintaining the Genome Stability and Working for the Common Good ENSG00000149311 ENSG00000136936 PMC4766464__F9 Loss of CEACAM1, a Tumor-Associated Factor, Attenuates Post-infarction Cardiac Remodeling by Inhibiting Apoptosis ENSG00000128272 ENSG00000144895 PMC524243__F1 Simplified model of insulin signaling ENSG00000005882 ENSG00000146678 ENSG00000102003 PMC4423889__F3 Analysis of Glioblastoma Patients' Plasma Revealed the Presence of MicroRNAs with a Prognostic Impact on Survival and Those of Viral Origin ENSG00000136997 ENSG00000158825 ENSG00000092067 ENSG00000269404 PMC3270444__F5 Putative inhibitory pathway of LPS-activated inflammatory signaling responses by peptide K5 ENSG00000183735 ENSG00000291971 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC7279404__F2 Summary of the liquid biopsies activating chemoattraction signal pathways for recruiting immune cells in NASH/NAFLD ENSG00000178860 ENSG00000169245 ENSG00000239732 ENSG00000130649 ENSG00000120889 PMC9507402__F2 Microglial pyroptosis: Therapeutic target in secondary brain injury following intracerebral hemorrhage ENSG00000278718 ENSG00000147697 ENSG00000073605 PMC9507402__F3 Microglial pyroptosis: Therapeutic target in secondary brain injury following intracerebral hemorrhage ENSG00000278718 ENSG00000162711 ENSG00000171444 PMC11724515__F8 Sirtuins 1/3/4/6 exert disparate influences on stem cell differentiation and insulin secretion ENSG00000139515 ENSG00000077463 ENSG00000142082 ENSG00000089163 PMC7288973__F8 Schematic diagram depicting the anti-PCa mechanism of C10 ENSG00000171791 ENSG00000064012 ENSG00000164305 PMC11724515__F1 Mechanism of Sirtuins in the occurrence and development of obesity ENSG00000187531 ENSG00000042832 ENSG00000150907 ENSG00000159346 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000168610 PMC11724515__F3 Mechanisms by which the FTO and TBX15 genes regulate obesity and osteoporosis ENSG00000178860 ENSG00000077463 PMC11724515__F2 Specific mechanism by which Sirtuins regulate the occurrence of osteoporosis ENSG00000187531 ENSG00000167941 ENSG00000168036 ENSG00000096717 ENSG00000142082 ENSG00000131196 ENSG00000004848 ENSG00000283100 PMC11724515__F5 Oestrogen, melatonin and NPY on obesity and bone ENSG00000162711 ENSG00000167941 ENSG00000168036 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000026103 PMC4889582__F2 TLRs reside on the plasma membrane or intracellularly on endosomes and act via the MyD88 or the TRIF pathway leading to the activation of downstream signaling pathways ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC11724515__F4 Vitamin D on obesity and bone ENSG00000162711 ENSG00000042832 ENSG00000096717 PMC7805242__F5 MiTF in osteoclast differentiation ENSG00000170909 ENSG00000164935 ENSG00000081087 ENSG00000136235 ENSG00000103249 ENSG00000131196 ENSG00000143387 PMC11724515__F6 SIRT1 regulates the balance between lipogenic and osteogenic differentiation of mesenchymal stem cells ENSG00000159346 ENSG00000096717 PMC9204147__F4 Daily Intake of a Phaseolus vulgaris L. Snack Bar Attenuates Hypertriglyceridemia and Improves Lipid Metabolism-Associated Plasma Proteins in Mexican Women: A Randomized Clinical Trial ENSG00000145431 ENSG00000070193 ENSG00000167772 ENSG00000117525 ENSG00000135218 ENSG00000152785 ENSG00000100985 ENSG00000166090 ENSG00000162692 ENSG00000121807 ENSG00000273936 PMC5279777__F3 Transcriptome Analysis Reveals Comprehensive Insights into the Early Immune Response of Large Yellow Croaker (Larimichthys crocea) Induced by Trivalent Bacterial Vaccine ENSG00000162711 ENSG00000091592 ENSG00000175104 ENSG00000277943 PMC7175546__F2 DNA damage and replication checkpoints ENSG00000175054 ENSG00000164053 ENSG00000111602 PMC2943133__F2 Toll-like receptor (TLR) signalling is mediated by at least two distinct pathways ENSG00000172936 ENSG00000130159 ENSG00000150455 ENSG00000175104 ENSG00000135517 PMC7175546__F1 Participation of WEE1 kinases (Cdk1 inhibitors) and CDC25 phosphatases (Cdk1 activators) in the regulation of the activity of Cdk1 kinase during G2 and M phases ENSG00000175054 ENSG00000164053 PMC6711563__F3 Inhibition of the hedgehog pathway for the treatment of cancer using Itraconazole ENSG00000125398 ENSG00000198793 ENSG00000103222 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC8507016__F2 Wnt/Beta-catenin signaling pathway in the pathogenesis and treatment of multiple myeloma (review) ENSG00000281324 ENSG00000137673 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000078098 PMC11923325__F5 Downregulation of TLR signaling ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000185187 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC8507016__F1 Wnt/Beta-catenin signaling pathway in the pathogenesis and treatment of multiple myeloma (review) ENSG00000137673 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3649699__F2 Cerebral ischemia-reperfusion activates two major signaling pathways which exert an effect on NOD ENSG00000057593 ENSG00000171791 PMC8875540__F3 Transcriptomic Analysis of Fish Hosts Responses to Nervous Necrosis Virus ENSG00000101596 ENSG00000134321 ENSG00000101160 ENSG00000133106 ENSG00000151835 ENSG00000105246 ENSG00000069248 PMC8507016__F3 Wnt/Beta-catenin signaling pathway in the pathogenesis and treatment of multiple myeloma (review) ENSG00000104432 PMC6711563__F2 In an adult cell, Hh pathway is always silent or poorly activated ENSG00000164690 ENSG00000128602 PMC9083465__F11 Integrating Lipidomics and Transcriptomics Reveals the Crosstalk Between Oxidative Stress and Neuroinflammation in Central Nervous System Demyelination ENSG00000051523 ENSG00000042832 ENSG00000173599 PMC8909644__F3 Synergistic Anti-Ageing through Senescent Cells Specific Reprogramming ENSG00000115419 PMC11240772__F1 Active Canonical Wnt/Beta-Catenin Signaling Pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11240772__F2 Inactive Canonical Wnt/Beta-Catenin Signaling Pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11923325__F3 Involvement of TIR domain-containing adaptors in TLR signaling pathways ENSG00000174125 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC11923325__F2 Structure and mechanism of TLR4, highlighting both MyD88-dependent and MyD88-independent pathways ENSG00000172936 ENSG00000136869 PMC5662721__F4 Type I interferon pathway gene network predicted by IPA analysis ENSG00000124102 ENSG00000053438 ENSG00000113161 ENSG00000115816 ENSG00000100815 ENSG00000065243 ENSG00000109854 ENSG00000142910 ENSG00000134321 ENSG00000049130 ENSG00000133110 ENSG00000163558 ENSG00000165953 ENSG00000198125 ENSG00000115419 ENSG00000033867 PMC3754482__F6 Glycocode model: 3-OST-5 and 3-OST-6 regulate distinct cell signaling pathways for ciliogenesis and cilia motility ENSG00000101350 ENSG00000087903 ENSG00000077782 PMC5477485__F2 Conserved insulin-signaling pathway in the ovary ENSG00000169047 ENSG00000133124 ENSG00000140443 PMC4281383__F4 Differential expression in LCI ENSG00000168028 ENSG00000124256 ENSG00000265681 ENSG00000213928 ENSG00000187608 ENSG00000089127 ENSG00000105939 ENSG00000157601 ENSG00000033800 ENSG00000115267 ENSG00000185745 ENSG00000185885 ENSG00000160710 ENSG00000125347 ENSG00000230034 ENSG00000276561 ENSG00000068079 ENSG00000173369 ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000185201 ENSG00000125538 ENSG00000142089 PMC3990718__F9 Deficient IFN Signaling by Myeloid Cells Leads to MAVS-Dependent Virus-Induced Sepsis ENSG00000162711 ENSG00000088888 ENSG00000125538 PMC7460884__F3 MCSs regulating cholesterol trafficking to the ER ENSG00000119655 ENSG00000141458 ENSG00000101558 PMC6213163__F7 Luteolin and Toll-like receptor signaling pathway ENSG00000182578 ENSG00000187554 ENSG00000108688 ENSG00000129226 PMC7579710__F6 Potential mechanisms of PB2‐induced apoptosis in OS cells ENSG00000108582 ENSG00000171791 PMC6213163__F5 Gene transcription pattern related to the TLR signaling pathway in white adipose tissue ENSG00000239732 ENSG00000144410 ENSG00000170458 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000164342 ENSG00000143387 PMC5477485__F1 Insulin-dependent signal transduction pathways ENSG00000002330 ENSG00000010810 ENSG00000198793 ENSG00000164327 PMC6779911__F6 Configuration of organellar GS-GOGAT cycles and split-organelle arginine biosynthesis ENSG00000250799 ENSG00000122966 PMC9455833__F2 Fatty Acid-Binding Proteins: Their Roles in Ischemic Stroke and Potential as Drug Targets ENSG00000125538 PMC5399176__F8 Proposed mechanism for ion flux-dependent regulation of the NLRP3 inflammasome ENSG00000162711 ENSG00000125538 PMC5701650__F1 STRESS ADAPTATION ENSG00000284774 PMC7920050__F1 Biogenesis of exosomes ENSG00000041353 PMC5843510__F8 Nocturnal activation of melatonin receptor type 1 signaling modulates diurnal insulin sensitivity via regulation of PI3K activity ENSG00000133124 PMC8330548__F2 Cadmium Exposure on the Immune System and Immunoregulation ENSG00000162711 ENSG00000079999 PMC2935201__F3 Platelets, Petechiae, and Preservation of the Vascular Wall ENSG00000138798 ENSG00000168036 ENSG00000112715 ENSG00000146648 PMC2917385__F1 Tumor Microenvironment in Non-Small Cell Lung Cancer ENSG00000198793 ENSG00000146648 PMC7695978__F1 miR-363 Alleviates Detrusor Fibrosis via the TGFB1/Smad Signaling Pathway by Targeting Col1a2 in Rat Models of STZ-Induced T2DM PMC6357186__F6 KRT19 and Wnt/beta-catenin/Notch signaling pathway in colon and breast cancers ENSG00000138795 ENSG00000133961 ENSG00000171345 PMC10778261__F8 Modulation of PI3K/AKT/TORC1 signaling pathway and AMPK activity downstream of M2 mAChR activation by APE or N8 in U251 and GB7 cell lines ENSG00000177169 ENSG00000198793 PMC7694542__F3 Conservation of signalling pathway proteins in Myxococcaceae ENSG00000138380 PMC7379745__F1 Macrophage M2b polarization ENSG00000131323 ENSG00000175104 PMC2790417__F10 Summary of proposed role for Foxa2, Nodal and Hh signalling pathways in ventral CNS development ENSG00000160973 ENSG00000156574 ENSG00000065320 PMC7947301__F1 Regulatory activities of nuclear receptors on the NLRP3 inflammasome priming and activation steps ENSG00000278718 ENSG00000162711 ENSG00000150782 ENSG00000185515 ENSG00000115008 ENSG00000135218 ENSG00000125538 ENSG00000265972 ENSG00000110218 PMC6459338__F3 Classical and “back-door” pathways of androgen biosynthesis ENSG00000086696 ENSG00000151632 ENSG00000197888 ENSG00000196620 ENSG00000187134 PMC7921639__F1 Metrnl regulates the intracellular signaling pathway ENSG00000168610 ENSG00000275031 ENSG00000108840 PMC8389593__F4 Molecular Mechanisms of Functional Adrenocortical Adenoma and Carcinoma: Genetic Characterization and Intracellular Signaling Pathway ENSG00000291560 ENSG00000179142 PMC3074690__F1 The current model of the blood coagulation cascade ENSG00000003436 ENSG00000176971 PMC8389593__F3 Molecular Mechanisms of Functional Adrenocortical Adenoma and Carcinoma: Genetic Characterization and Intracellular Signaling Pathway ENSG00000281324 ENSG00000179142 PMC8389593__F2 Molecular Mechanisms of Functional Adrenocortical Adenoma and Carcinoma: Genetic Characterization and Intracellular Signaling Pathway ENSG00000163399 ENSG00000196557 ENSG00000179142 PMC8389593__F1 Molecular Mechanisms of Functional Adrenocortical Adenoma and Carcinoma: Genetic Characterization and Intracellular Signaling Pathway ENSG00000179142 PMC5498918__F1 Dibenzazepine-Loaded Nanoparticles Induce Local Browning of White Adipose Tissue to Counteract Obesity ENSG00000142611 ENSG00000114315 PMC8389593__F8 Molecular Mechanisms of Functional Adrenocortical Adenoma and Carcinoma: Genetic Characterization and Intracellular Signaling Pathway ENSG00000281324 ENSG00000184634 ENSG00000183579 PMC8389593__F5 Molecular Mechanisms of Functional Adrenocortical Adenoma and Carcinoma: Genetic Characterization and Intracellular Signaling Pathway ENSG00000143799 ENSG00000179142 ENSG00000203857 PMC2901643__F2 Putative signaling components in fungal mating interactions ENSG00000070831 ENSG00000180644 PMC3206202__F9 Expression Profiling Reveals Differential Gene Induction Underlying Specific and Non-Specific Memory for Pheromones in Mice ENSG00000002330 PMC5393036__F7 Schematic model of NKILA functions during the invasion-metastasis cascade in NSCLC PMC4457722__F5 Characterization of the Kallikrein-Kinin System Post Chemical Neuronal Injury: An In Vitro Biochemical and Neuroproteomics Assessment ENSG00000160789 ENSG00000132341 PMC11580298__F3 Network-based hub biomarker discovery for glaucoma ENSG00000204842 ENSG00000163947 ENSG00000157827 ENSG00000070366 ENSG00000145982 ENSG00000107902 ENSG00000120885 ENSG00000281879 ENSG00000023697 ENSG00000107249 ENSG00000142599 ENSG00000075420 ENSG00000112699 ENSG00000171408 PMC6779911__F2 Functional annotations of highly nitrate-sensitive (HNS) gene set and model of nitrate assimilation and regulatory components in Phaeodactylum tricornutum ENSG00000042832 ENSG00000062485 PMC11740368__F5 Pers expression regulates tumorigenesis ENSG00000168283 ENSG00000134057 ENSG00000198793 ENSG00000132326 ENSG00000168036 PMC4519914__F6 Protein–protein interaction (PPI) network and ingenuity pathway analysis (IPA) ENSG00000102390 ENSG00000012048 ENSG00000070756 ENSG00000183735 ENSG00000084676 ENSG00000066044 ENSG00000291971 ENSG00000184110 ENSG00000173674 ENSG00000185591 ENSG00000215301 ENSG00000187840 PMC5814291__F3 FOXC1, the new player in the cancer sandbox ENSG00000127445 ENSG00000138798 ENSG00000128602 ENSG00000146648 PMC5601978__F4 Physiological functions of ataxin-2 ENSG00000204842 ENSG00000163435 ENSG00000198793 ENSG00000092847 ENSG00000068383 ENSG00000069667 PMC11740368__F6 Cancer stem cell generation and mechanisms of PERs action on cancer stem cells ENSG00000132326 ENSG00000168036 PMC3295063__F2 NFKB in Aging and Disease ENSG00000149311 ENSG00000291603 ENSG00000102871 ENSG00000172936 ENSG00000168040 ENSG00000175104 ENSG00000127191 ENSG00000291368 PMC8599992__F10 Exploring the Structures and Functions of Macromolecular SLX4-Nuclease Complexes in Genome Stability ENSG00000149346 ENSG00000168214 ENSG00000188827 ENSG00000033800 ENSG00000164362 PMC9406090__F2 Let-7 as a Promising Target in Aging and Aging-Related Diseases: A Promise or a Pledge ENSG00000144535 ENSG00000131914 ENSG00000083223 ENSG00000187772 ENSG00000134744 ENSG00000113360 PMC2844177__F9 P38 MAPK signal transduction in melanogenesis ENSG00000080166 PMC8777575__F3 Gold complex auranofin: new perspectives for cancer therapy ENSG00000134982 ENSG00000189403 PMC8777575__F2 Gold complex auranofin: new perspectives for cancer therapy ENSG00000144895 ENSG00000198793 ENSG00000171791 ENSG00000118777 PMC4028208__F9 A summary schematic of the lansoprazole-induced AhR/Cyp1a1/Nrf2 pathway in the liver ENSG00000140465 ENSG00000106546 PMC1475884__F2 TNF receptor (TNFR) pathway of signaling ENSG00000102871 ENSG00000056558 ENSG00000168040 ENSG00000127191 PMC11831484__F10 Fatty Acid Oxidation‐Glycolysis Metabolic Transition Affects ECM Homeostasis in Silica‐Induced Pulmonary Fibrosis ENSG00000161533 ENSG00000159399 ENSG00000152556 PMC4640673__F2 ECM receptors in neuronal structure, synaptic plasticity, and behavior ENSG00000173406 PMC4679480__F8 Green Tea component EGCG, Insulin and IGF-1 promote nuclear efflux of atrophy associated transcription factor Foxo1 in skeletal muscle fibers ENSG00000150907 ENSG00000169047 PMC4346735__F1 Krüppel-like factor KLF10-mediated regulation of transforming growth factor (TGF)B signaling pathway in CD8+ and CD4+ T cells ENSG00000049768 ENSG00000155090 PMC9339612__F4 Long Non-Coding RNAs in Epithelial-Mesenchymal Transition-Related Signaling Pathways in Prostate Cancer PMC9339612__F3 Long Non-Coding RNAs in Epithelial-Mesenchymal Transition-Related Signaling Pathways in Prostate Cancer ENSG00000128342 ENSG00000168610 ENSG00000132341 PMC9339612__F2 Long Non-Coding RNAs in Epithelial-Mesenchymal Transition-Related Signaling Pathways in Prostate Cancer ENSG00000185591 PMC8379308__F1 Herpesviruses and the Type III Interferon System ENSG00000213928 ENSG00000239732 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC9339612__F1 Long Non-Coding RNAs in Epithelial-Mesenchymal Transition-Related Signaling Pathways in Prostate Cancer ENSG00000168036 ENSG00000103769 ENSG00000168610 PMC5386389__F8 ATG5-ATG12 involvement in FMDV-induced type IIFN signal pathway ENSG00000183735 ENSG00000131323 ENSG00000145782 ENSG00000057663 PMC4310451__F3 Differential effects of leptin and adiponectin in vascular endothelium ENSG00000285070 ENSG00000162692 ENSG00000168610 ENSG00000132693 PMC11603874__F11 Anti-TNFR2 bs-Ab mechanism of action ENSG00000178860 ENSG00000118520 ENSG00000146648 PMC7882969__F2 Signal pathways related with androgen synthesis in polycystic ovary syndrome (PCOS) ENSG00000162552 ENSG00000171105 ENSG00000134982 ENSG00000203859 ENSG00000168036 PMC4661210__F7 JNK1 exerts kinase activity on several transcription factors and BCL2 family proteins through phosphorylation or ubiquitination ENSG00000177606 ENSG00000171791 ENSG00000104081 PMC4661210__F6 Activation mechanisms of the ASK1 signaling pathway leading to JNK and p38MAPK phosphorylation ENSG00000082512 ENSG00000175104 ENSG00000127191 PMC4661210__F3 Activation mechanism of NRF2 and downstream transcription events ENSG00000275331 ENSG00000181019 ENSG00000271303 ENSG00000118777 ENSG00000023909 ENSG00000124588 ENSG00000023839 ENSG00000079999 ENSG00000262243 PMC6567798__F1 LncRNAs regulate p53 signaling pathway through MDM2 ENSG00000149311 PMC3423855__F1 Hepatocellular processing of, and immune modulation by, the precore protein ENSG00000172005 ENSG00000172936 PMC7191303__F1 Hippo–YAP1/TAZ pathway in cardiac biology ENSG00000117713 ENSG00000186575 ENSG00000166025 ENSG00000150457 ENSG00000131023 ENSG00000178568 PMC5546324__F6 AKT/PKB Signaling: Navigating the Network ENSG00000033327 ENSG00000138798 ENSG00000169047 ENSG00000136111 ENSG00000146648 ENSG00000140443 PMC6237576__F3 Contributions of PCAF‐induced acetylation to the development of liver injury and mediators of inflammation ENSG00000134982 ENSG00000049768 ENSG00000096717 ENSG00000155090 PMC6492362__F7 Gelsolin-like actin-capping protein has prognostic value and promotes tumorigenesis and epithelial-mesenchymal transition via the Hippo signaling pathway in human bladder cancer ENSG00000150457 ENSG00000131023 PMC8905633__F4 Revealing Calcium Signaling Pathway as Novel Mechanism of Danhong Injection for Treating Acute Myocardial Infarction by Systems Pharmacology and Experiment Validation ENSG00000142192 ENSG00000291971 ENSG00000175591 ENSG00000180772 ENSG00000121807 ENSG00000121879 ENSG00000168610 ENSG00000274286 ENSG00000164305 ENSG00000102468 ENSG00000121966 ENSG00000133019 ENSG00000177606 PMC4486162__F1 Apoptosis: role in myeloid cell development ENSG00000102871 ENSG00000168040 ENSG00000026103 PMC6237576__F4 Contributions of PCAF‐induced acetylation to the development of hepatocellular carcinoma and liver cancer tumour growth ENSG00000198793 PMC8905633__F7 Revealing Calcium Signaling Pathway as Novel Mechanism of Danhong Injection for Treating Acute Myocardial Infarction by Systems Pharmacology and Experiment Validation ENSG00000142192 ENSG00000291971 ENSG00000177606 ENSG00000121879 ENSG00000168610 ENSG00000146648 PMC7296212__F6 Mechanism of NRF2 activation by oxidative stress ENSG00000100387 ENSG00000079999 PMC3861981__F5 A simplified schematic diagram of the neural circuitry underlying eyeblink conditioning ENSG00000173599 ENSG00000145321 ENSG00000062485 PMC10708062__F8 Analysis of DEGs involved in carbon fixation under osmotic stress ENSG00000197713 ENSG00000153574 ENSG00000146701 PMC3660156__F4 Tumour dormancy and clinical implications in breast cancer ENSG00000138798 ENSG00000146648 ENSG00000122194 PMC5538252__F4 Sepsis and septic shock ENSG00000005381 PMC6566596__F4 Cross-talks between tumor and immune cells determining chemo-immune-resistance ENSG00000184207 PMC8921626__F4 Identification of Dose-Dependent DNA Damage and Repair Responses From Subchronic Exposure to 1,4-Dioxane in Mice Using a Systems Analysis Approach ENSG00000174307 ENSG00000113328 ENSG00000159388 ENSG00000125968 ENSG00000138356 PMC12006732__F3 Communication between the gut microbiota and other organs ENSG00000160867 ENSG00000114416 ENSG00000167910 PMC11447943__F2 Main interactions of TRPC5 channel with signaling proteins in a cellular context ENSG00000065054 ENSG00000167323 ENSG00000293604 ENSG00000109062 ENSG00000072315 ENSG00000119125 PMC3046044__F1 Molecular mechanisms involved in nasopharyngeal carcinoma (NPC) development ENSG00000132478 PMC3905242__F1 MRE11 complex: starting from the ends ENSG00000149311 ENSG00000175054 ENSG00000197299 ENSG00000123374 PMC6920374__F6 The role of Wnt signaling in hiPSC-CM differentiation ENSG00000166823 ENSG00000164736 ENSG00000128052 ENSG00000134853 PMC3905242__F4 MRE11 complex: starting from the ends ENSG00000188486 ENSG00000149311 PMC6343537__F2 Putative pathway for antagonistic Rab35/Arf6 regulation in presynaptic terminals ENSG00000162065 ENSG00000114331 PMC4054936__F2 Tonic regulation of vascular permeability ENSG00000019991 ENSG00000156299 ENSG00000134982 ENSG00000149269 PMC8509209__F6 LEF1 Enhances the Progression of Colonic Adenocarcinoma via Remodeling the Cell Motility Associated Structures ENSG00000134982 ENSG00000168036 PMC10242022__F1 Protein kinases on carbon metabolism: potential targets for alternative chemotherapies against toxoplasmosis ENSG00000152782 ENSG00000103507 ENSG00000138621 ENSG00000127125 ENSG00000026103 PMC8282538__F6A Molecular processes mediating hyperhomocysteinemia-induced metabolic reprogramming, redox regulation and growth inhibition in endothelial cells ENSG00000261832 ENSG00000124217 ENSG00000059804 ENSG00000171723 ENSG00000136877 ENSG00000157601 ENSG00000134575 ENSG00000138074 ENSG00000138621 ENSG00000127125 ENSG00000115750 ENSG00000103174 ENSG00000157064 ENSG00000068120 ENSG00000040531 PMC6489690__F4 MicroRNAs as Potential Targets for Therapeutic Intervention With Metastasis of Non-small Cell Lung Cancer ENSG00000114978 ENSG00000061337 ENSG00000198670 ENSG00000131023 PMC6489690__F3 MicroRNAs as Potential Targets for Therapeutic Intervention With Metastasis of Non-small Cell Lung Cancer ENSG00000156076 ENSG00000168036 PMC8304577__F9 Analysis of Phytohormone Signal Transduction in Sophora alopecuroides under Salt Stress ENSG00000110921 ENSG00000113161 ENSG00000132840 ENSG00000167508 ENSG00000116761 PMC4824422__F3 Pathway Network Analyses for Autism Reveal Multisystem Involvement, Major Overlaps with Other Diseases and Convergence upon MAPK and Calcium Signaling ENSG00000100346 ENSG00000008735 ENSG00000274542 ENSG00000102001 ENSG00000133019 ENSG00000184845 ENSG00000148408 ENSG00000196557 ENSG00000157087 ENSG00000166501 ENSG00000135124 ENSG00000196712 ENSG00000156049 ENSG00000157764 ENSG00000152495 ENSG00000050628 ENSG00000115590 ENSG00000006283 ENSG00000182621 ENSG00000081189 ENSG00000102468 ENSG00000087460 ENSG00000007171 ENSG00000177189 ENSG00000176884 ENSG00000154678 ENSG00000148680 ENSG00000157445 ENSG00000178568 PMC3931400__F3 Signaling by leptin, Wnt, and Beta-catenin in the regulation of Beta-cell proliferation ENSG00000134982 ENSG00000169047 ENSG00000168036 ENSG00000164093 ENSG00000118971 PMC3931400__F2 Signaling by EGF and PDGF in the regulation of Beta-cell proliferation ENSG00000065361 ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000146648 ENSG00000178568 PMC5108608__F1 Diagram of possible GPC3-mediated signaling pathway in HCC progression.Abbreviations: GPC-3, glypican-3; HCC, hepatocellular carcinoma; P, Phosphorylation ENSG00000002330 ENSG00000136997 ENSG00000168036 ENSG00000100985 PMC8789910__F7 Illustration of proposed mechanism ENSG00000094631 ENSG00000070831 ENSG00000087586 ENSG00000148384 PMC8940216__F5 Different Roles of Resident and Non-resident Macrophages in Cardiac Fibrosis ENSG00000125538 ENSG00000172936 ENSG00000121807 PMC9922515__F7 Solanine Represses Gastric Cancer Growth by Mediating Autophagy Through AAMDC/MYC/ATF4/Sesn2 Signaling Pathway ENSG00000087884 ENSG00000128272 ENSG00000136997 ENSG00000285069 PMC5485992__F2 Neuronal defense systems ENSG00000142192 ENSG00000181019 ENSG00000198793 ENSG00000119912 ENSG00000077782 ENSG00000023909 ENSG00000105227 PMC11130840__F1 PCP-mediated signaling pathway in Drosophila and mouse ENSG00000004975 ENSG00000107404 ENSG00000173218 ENSG00000143126 ENSG00000075275 ENSG00000008300 ENSG00000161202 PMC10620037__F4 IL-37 inhibits hepatocellular carcinoma (HCC) ENSG00000198793 PMC9112923__F5 Identification of Alzheimer’s Disease Molecular Subtypes Based on Parallel Large-Scale Sequencing ENSG00000162409 ENSG00000138798 ENSG00000136997 ENSG00000096717 ENSG00000146648 ENSG00000124762 PMC10620037__F3 IL-37 inhibits liver fibrosis ENSG00000170365 ENSG00000136535 ENSG00000125968 PMC4564160__F3 SILAC-Based Mass Spectrometry Analysis Reveals That Epibrassinolide Induces Apoptosis via Activating Endoplasmic Reticulum Stress in Prostate Cancer Cells ENSG00000204842 ENSG00000189367 ENSG00000171403 ENSG00000103657 ENSG00000151835 ENSG00000227345 ENSG00000105379 ENSG00000133805 PMC11901428__F1 Host-microbiota interactome in IBD ENSG00000187554 ENSG00000170989 ENSG00000180739 ENSG00000213694 ENSG00000125910 ENSG00000267534 ENSG00000106546 PMC8282538__F5A Molecular processes mediating hyperhomocysteinemia-induced metabolic reprogramming, redox regulation and growth inhibition in endothelial cells ENSG00000242265 ENSG00000164736 ENSG00000006282 ENSG00000165507 ENSG00000204977 ENSG00000099282 ENSG00000221926 PMC11899125__F3 Immune-checkpoint signaling PMC11899125__F1 Signal Transduction Pathways of Co-inhibitory Immune Checkpoints ENSG00000089692 ENSG00000181847 PMC11899125__F6 Primary resistance ENSG00000169245 ENSG00000089692 ENSG00000163599 ENSG00000198793 ENSG00000138755 ENSG00000168036 ENSG00000198846 ENSG00000273686 ENSG00000146648 PMC4765374__F1 Molecular mechanisms of ethanol-associated OESCC ENSG00000170458 ENSG00000130649 ENSG00000136869 ENSG00000164690 PMC5974248__F3 Involvement of optineurin in nuclear factor kappa B (NFKB) signaling ENSG00000183735 ENSG00000123240 ENSG00000172936 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC2864807__F2 PPAR Signaling Pathway and Cancer-Related Proteins in Celiac Disease-Associated Tissue Damage ENSG00000117054 ENSG00000145384 PMC2066195__F10 IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000115594 PMC9453641__F1 Gamble between oncolytic virus therapy and IFN ENSG00000159128 ENSG00000213928 ENSG00000105397 ENSG00000168610 PMC8759529__F1 Histiocytoses converge through common pathways ENSG00000110395 ENSG00000198793 ENSG00000179295 PMC12104182__F3 Possible mechanisms by which periodontal pathogens may promote activation of the Wnt/Beta-catenin pathway during oral carcinogenesis ENSG00000107404 ENSG00000134982 PMC2794543__F8 Activation of Wnt/Beta-Catenin Signaling Increases Insulin Sensitivity through a Reciprocal Regulation of Wnt10b and SREBP-1c in Skeletal Muscle Cells ENSG00000169884 ENSG00000168036 PMC9029738__F2 Towards Kinase Inhibitor Therapies for Fragile X Syndrome: Tweaking Twists in the Autism Spectrum Kinase Signaling Network ENSG00000198793 ENSG00000198576 ENSG00000100985 PMC2751986__F7 Rev-erbA/PGC-1A pathway regulating heme homeostasis ENSG00000106459 ENSG00000069667 PMC3622753__F1 Intracellular S100B on cell proliferation, differentiation, survival and motility ENSG00000038382 ENSG00000070831 ENSG00000291971 ENSG00000005882 ENSG00000135446 ENSG00000138798 PMC7930375__F1 Vitamin D (both D3 and D2) metabolic pathway and its physiological impact on immune cells ENSG00000111012 ENSG00000205221 ENSG00000186104 PMC12010983__SF1 Graphical abstract ENSG00000151012 ENSG00000167996 ENSG00000163734 ENSG00000163737 PMC4453272__F2 Fragile X Mental retardation protein regulates several cellular functions in the dendritic spine ENSG00000106683 ENSG00000092847 ENSG00000291561 ENSG00000196712 PMC9658244__F3 IL-33/ST2 Pathway in Cerebral Malaria ENSG00000169245 ENSG00000108691 ENSG00000137033 ENSG00000125538 PMC9658244__F2 IL-33/ST2 Pathway in Cerebral Malaria ENSG00000137033 ENSG00000125538 ENSG00000113525 PMC8013494__F1 COVID‐19 and Liver Cirrhosis: Focus on the Nonclassical Renin‐Angiotensin System and Implications for Therapy ENSG00000175054 ENSG00000130234 PMC8964154__F7 Identifying Active Substances and the Pharmacological Mechanism of Houttuynia cordata Thunb. in Treating Radiation-Induced Lung Injury Based on Network Pharmacology and Molecular Docking Verification ENSG00000177455 ENSG00000142192 ENSG00000078747 ENSG00000179091 ENSG00000186716 PMC4171726__F4 Endothelial versus cancer metabolism ENSG00000159224 ENSG00000178445 ENSG00000115419 PMC9494650__F6 Proteomic and Metabolomic Revealed Differences in the Distribution and Synthesis Mechanism of Aroma Precursors in Yunyan 87 Tobacco Leaf, Stem, and Root at the Seedling Stage ENSG00000131473 ENSG00000196839 ENSG00000038002 PMC9552878__F4 Two facets of receptor tyrosine kinase in cardiovascular calcification—can tyrosine kinase inhibitors benefit cardiovascular system? ENSG00000118972 ENSG00000105550 ENSG00000120149 ENSG00000077782 PMC6316616__F2 HSV-1 deregulates host miRNAs ENSG00000111537 ENSG00000070831 ENSG00000132463 ENSG00000107863 ENSG00000000971 ENSG00000125347 PMC6444510__F1 cGAS-STING pathway ENSG00000183735 ENSG00000164430 ENSG00000134287 PMC7203694__F8 Plausible mechanism of CeO2-induced apoptosis of human colon cancer cells (HCT 116) by ROS-generated mitochondrial-mediated pathway ENSG00000120868 ENSG00000171791 ENSG00000164305 PMC5486401__F2 Beyond TNF: TNF superfamily cytokines as targets for the treatment of rheumatic diseases ENSG00000104856 ENSG00000102871 ENSG00000173039 ENSG00000168040 PMC9520222__F8 Ion elemental-optimized layered double hydroxide nanoparticles promote chondrogenic differentiation and intervertebral disc regeneration of mesenchymal stem cells through focal adhesion signaling pathway ENSG00000125398 ENSG00000070831 ENSG00000291748 ENSG00000108821 PMC11566475__F9 Metabolic pathway gene association network ENSG00000109929 ENSG00000117399 PMC7550629__F3 TRP- small GTPases signaling pathways interplay in aberrant tumor vascularization ENSG00000144935 ENSG00000137672 PMC8458655__F9 Research Progress on the Functions and Mechanism of circRNA in Cisplatin Resistance in Tumors ENSG00000162433 ENSG00000114416 ENSG00000078399 ENSG00000103222 ENSG00000168610 ENSG00000009413 PMC8945564__F6 Quantitative Metabolomics of Tissue, Perfusate, and Bile from Rat Livers Subjected to Normothermic Machine Perfusion ENSG00000291507 ENSG00000173599 PMC6909348__F2 CLCA1 on mucus production ENSG00000291363 ENSG00000016490 ENSG00000124664 PMC4303633__F5 Metabolic scheme of ectoine, glutamate and proline synthesis and catabolism inferred from the Nitrosopumilus genomes ENSG00000122882 ENSG00000173599 ENSG00000100033 ENSG00000062485 PMC3920008__F4 Novel regulatory pathway of intracellular lipid homeostasis ENSG00000180432 ENSG00000135929 ENSG00000026103 PMC9526673__F6 Identification of Interleukin-1-Beta Inhibitors in Gouty Arthritis Using an Integrated Approach Based on Network Pharmacology, Molecular Docking, and Cell Experiments ENSG00000152684 PMC6187079__F1 Mammalian autophagy-lysosomal pathway (ALP) ENSG00000094631 ENSG00000177169 ENSG00000110497 ENSG00000152348 ENSG00000123395 ENSG00000126775 ENSG00000148400 ENSG00000115363 ENSG00000198793 ENSG00000112561 ENSG00000168036 ENSG00000188554 ENSG00000144848 ENSG00000284099 ENSG00000145782 PMC6955744__F5 TGFB signaling pathway with mediators in the TGFB pathway and BMP pathway are depicted, adapted from IPA ENSG00000037965 ENSG00000157933 ENSG00000133937 ENSG00000115297 ENSG00000156574 ENSG00000164093 PMC11910004__F7 Epimedium brevicornum Maxim alleviates diabetes osteoporosis by regulating AGE-RAGE signaling pathway ENSG00000087245 ENSG00000115415 ENSG00000135446 ENSG00000150907 ENSG00000137193 ENSG00000007908 ENSG00000162692 ENSG00000168610 ENSG00000164305 ENSG00000178726 ENSG00000131196 PMC3033158__F3 Signal pathways in systemic regulation of hepcidin ENSG00000010704 ENSG00000106327 ENSG00000105697 ENSG00000130513 PMC11603874__F8 Signals from Mb-TNFA/TNFR2 stimulate HIF-1A, CXCR4, and PD-L1 ENSG00000134086 ENSG00000107562 ENSG00000128272 ENSG00000177606 ENSG00000136997 ENSG00000162924 ENSG00000168610 ENSG00000146648 ENSG00000121966 PMC8831980__F2 Fibroblast growth factor 8 in cartilage development and disease ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC11603874__F7 TNFR2 supports BCSC growth and development ENSG00000136997 ENSG00000019549 ENSG00000026508 ENSG00000127191 ENSG00000168610 ENSG00000146648 PMC11603874__F6 TNFA/TNFR2-mediated invasion and metastasis in BC TME ENSG00000163464 ENSG00000019991 ENSG00000108691 ENSG00000122691 ENSG00000121807 ENSG00000168610 ENSG00000146648 ENSG00000121966 PMC7031469__F1 Action of metformin in the neuro-glial environment ENSG00000177169 ENSG00000142192 ENSG00000104321 ENSG00000013441 ENSG00000125538 ENSG00000198793 ENSG00000096717 PMC11603874__F4 TNFR2/Mb-TNFA signalosome pathway ENSG00000104856 ENSG00000107562 ENSG00000198793 ENSG00000232326 ENSG00000168036 ENSG00000102010 ENSG00000127191 ENSG00000168610 ENSG00000121966 ENSG00000041982 ENSG00000138336 ENSG00000083799 ENSG00000100985 ENSG00000175104 ENSG00000146648 ENSG00000115009 PMC4871335__F2 High Phosphorus Diet Affects Lipid Metabolism in Rat Liver: A DNA Microarray Analysis ENSG00000135423 ENSG00000262635 ENSG00000171759 ENSG00000100033 ENSG00000183077 ENSG00000166123 ENSG00000178445 ENSG00000167701 PMC4871335__F3 High Phosphorus Diet Affects Lipid Metabolism in Rat Liver: A DNA Microarray Analysis ENSG00000131473 ENSG00000177465 ENSG00000170522 ENSG00000134824 ENSG00000095321 ENSG00000167910 ENSG00000113161 ENSG00000104549 ENSG00000197977 ENSG00000169710 ENSG00000104325 ENSG00000005469 PMC3820512__F5 Linking Transcriptional Changes over Time in Stimulated Dendritic Cells to Identify Gene Networks Activated during the Innate Immune Response ENSG00000141551 ENSG00000168036 ENSG00000171791 ENSG00000150455 ENSG00000121966 ENSG00000089159 ENSG00000132326 ENSG00000185591 ENSG00000184900 ENSG00000081041 ENSG00000178078 ENSG00000115993 ENSG00000109320 ENSG00000168040 ENSG00000168610 ENSG00000117322 ENSG00000277943 ENSG00000120805 ENSG00000161921 ENSG00000115415 ENSG00000100387 ENSG00000173757 ENSG00000172936 ENSG00000131323 ENSG00000184216 PMC7384693__F6 Cu-TA’s Biological Targets in MIA PaCa-2 Cells ENSG00000145604 ENSG00000117724 ENSG00000185591 ENSG00000168610 PMC2749448__F1 Transcriptional Regulation of Carbohydrate Metabolism in the Human Pathogen Candida albicans ENSG00000074800 ENSG00000090863 ENSG00000139515 ENSG00000124253 ENSG00000169299 PMC3713536__F2 Anticoagulant and cytoprotective actions of the protein C pathway ENSG00000134982 PMC7384693__F2 Overlapping Networks and Selection of Network #7 for Further Analysis ENSG00000012061 ENSG00000111057 ENSG00000175793 ENSG00000178999 ENSG00000159388 ENSG00000291803 ENSG00000122565 ENSG00000075218 ENSG00000171345 ENSG00000108840 PMC8599883__F1 Zinc in female reproduction ENSG00000172680 ENSG00000134057 ENSG00000134982 ENSG00000172572 ENSG00000159899 ENSG00000101224 ENSG00000146648 PMC7384693__F1 Merged Networks (Core of #1 Overlapping Networks) ENSG00000157554 ENSG00000205250 ENSG00000070669 ENSG00000145431 ENSG00000012048 ENSG00000100290 ENSG00000184384 ENSG00000128052 ENSG00000136997 ENSG00000004487 ENSG00000185591 ENSG00000122565 ENSG00000128342 ENSG00000178719 ENSG00000283060 ENSG00000115419 ENSG00000109670 ENSG00000023445 ENSG00000168209 ENSG00000135100 ENSG00000196954 ENSG00000107447 ENSG00000116675 ENSG00000262145 ENSG00000128272 ENSG00000101849 ENSG00000166321 ENSG00000132646 ENSG00000068745 ENSG00000029993 ENSG00000131196 ENSG00000023839 ENSG00000130726 PMC2880683__F1 Insulin signaling pathway ENSG00000005882 ENSG00000169047 ENSG00000198793 ENSG00000164327 PMC3080979__F2 Partial hepatectomy stimulates anandamide production through a pathway involving conjugation of arachidonic acid and ethanolamine by FAAH ENSG00000117480 PMC7286322__F4 LncRNA PTTG3P played different roles in different stages of NSCLC ENSG00000108055 ENSG00000077152 ENSG00000196504 ENSG00000135476 ENSG00000073111 ENSG00000145386 ENSG00000117399 ENSG00000093009 ENSG00000183765 ENSG00000012048 ENSG00000094804 ENSG00000065613 ENSG00000144554 ENSG00000119953 ENSG00000136997 ENSG00000162607 ENSG00000114503 ENSG00000164167 ENSG00000177084 ENSG00000133119 ENSG00000095002 ENSG00000175305 PMC7951058__F4 Molecular pathway and network analysis of proteomics analysis of differentially expressed proteins in LTLT-Ca mammospheres and LTLT-Ca adherent cells ENSG00000128989 ENSG00000100883 ENSG00000104980 ENSG00000173726 ENSG00000153048 ENSG00000092108 ENSG00000103381 ENSG00000135093 ENSG00000141456 PMC11036065__F2 Molecular targeted therapies for cutaneous squamous cell carcinoma: recent developments and clinical implications ENSG00000162337 ENSG00000167074 PMC4815360__F3 Schematic diagram illustrating synthesis of ET peptides and interaction with receptors ENSG00000140564 ENSG00000117298 ENSG00000151617 PMC2077852__F3 Dmp1 links the Rb and p53 pathways ENSG00000168283 ENSG00000121068 ENSG00000135446 ENSG00000136997 ENSG00000152592 ENSG00000135111 PMC8814438__F7 Kinsenoside Protects Against Radiation-Induced Liver Fibrosis via Downregulating Connective Tissue Growth Factor Through TGFB1 Signaling ENSG00000105329 PMC3591094__F8 LPA-LPAR1/3 GAi2–mediated activation of p130Cas in cell migration ENSG00000291971 ENSG00000163914 ENSG00000198670 PMC6769793__F4 Metabolic pathway of classic and non-classic androgens ENSG00000086696 ENSG00000277893 ENSG00000203859 ENSG00000203857 ENSG00000127948 ENSG00000176387 PMC8924072__F6 Proteomic Analysis Suggests Altered Mitochondrial Metabolic Profile Associated With Diabetic Cardiomyopathy ENSG00000265681 ENSG00000179091 ENSG00000099624 ENSG00000129824 ENSG00000164327 ENSG00000125656 ENSG00000089159 PMC9453641__F3 Gamble between oncolytic virus therapy and IFN ENSG00000168610 PMC3682751__F3 Decreased translation of Dio3 mRNA is associated with drug-induced hepatotoxicity ENSG00000148798 PMC3901118__F3 Overview of the Ras/PKA pathway and relevant regulatory connections involved in the yeast pseudohyphal growth and autophagy responses ENSG00000196511 PMC6949817__F8 Schematic presentation of the CBFB/RUNX3-miR10b-TIAM1 pathway ENSG00000156299 ENSG00000020633 ENSG00000067955 PMC7395702__F1 Signal Transduction Pathway of PD-1 / PD-L1 ENSG00000213658 ENSG00000198793 PMC6468297__F3 MDM2’s switch from a negative to a positive regulator of p53 following DNA damage is dependent on the p53 mRNA ENSG00000149311 PMC4278616__F2 Signaling modulating adherens junctions (AJs) ENSG00000163914 PMC11959147__F1 Illustration of the PI3K (left) and TP53, inside the nucleus, (right) signaling pathways [21, 22] ENSG00000149311 ENSG00000175054 ENSG00000155792 ENSG00000183765 PMC9365119__F1 Non-ionotropic NMDAR signaling in neuronal physiology ENSG00000291971 ENSG00000198929 ENSG00000110218 ENSG00000196689 PMC6468297__F1 Cell stress-dependent regulation of alternative initiation of p53 mRNA translation ENSG00000149311 PMC7710136__F9 Cross-talk between metabolic, inflammatory and muscle growth pathways in dystrophic muscle ENSG00000111537 ENSG00000070831 ENSG00000164327 ENSG00000096717 ENSG00000081189 PMC7266940__F3 Deeply characterized cellular processes affected by miRNAs in MB ENSG00000198793 ENSG00000105810 ENSG00000164690 ENSG00000114315 ENSG00000128602 PMC2613033__F1 Genome-Wide Association Study of Plasma Polyunsaturated Fatty Acids in the InCHIANTI Study ENSG00000134824 ENSG00000149485 ENSG00000197977 PMC10459190__F2 Molecular mechanisms involved in atherogenic effects of Cd exposure ENSG00000162711 ENSG00000005421 ENSG00000162692 ENSG00000168610 PMC7210388__F8 GPR50 Promotes Hepatocellular Carcinoma Progression via the Notch Signaling Pathway through Direct Interaction with ADAM17 ENSG00000283780 ENSG00000102195 ENSG00000185591 ENSG00000114315 PMC9273281__F1 Senescence-associated secretory phenotype in ovarian cancer dissemination ENSG00000145388 ENSG00000164430 ENSG00000104885 ENSG00000164104 ENSG00000165819 PMC4250228__F1 Methylation Matters In KRAS Oncogenesis ENSG00000113070 ENSG00000146648 PMC9298824__F1 Glimpse of Inflammation and Anti-Inflammation Therapy in Diabetic Kidney Disease ENSG00000162711 ENSG00000239732 ENSG00000164430 ENSG00000163568 PMC6562901__F1 TGFB Signaling ENSG00000198793 PMC5702541__F3 MSCs secretome and tumor stemness ENSG00000178860 ENSG00000163739 ENSG00000138798 ENSG00000196154 ENSG00000124875 ENSG00000100985 ENSG00000168610 ENSG00000121966 PMC6952548__F7 HCMV miRNA-mediated regulation of TGFB production and signaling during viral latency and reactivation in CD34+ HPCs ENSG00000196591 ENSG00000138386 ENSG00000174059 PMC10487916__F3 miRNA–mRNA network based on the target genes of miR-141-3p, miR-150-5p, miR-182-5p, and miR-661 (obtained from the Integrated Breast Cancer Pathway (Wikipathways)) ENSG00000070831 ENSG00000169047 ENSG00000087586 ENSG00000277273 ENSG00000069956 ENSG00000171791 ENSG00000166484 ENSG00000166851 ENSG00000112715 ENSG00000164305 ENSG00000163349 ENSG00000012048 ENSG00000172992 ENSG00000150907 ENSG00000123374 ENSG00000185591 ENSG00000107779 ENSG00000003436 ENSG00000109320 ENSG00000033800 ENSG00000064393 ENSG00000116717 ENSG00000173402 ENSG00000149311 ENSG00000115415 ENSG00000135446 ENSG00000095002 ENSG00000146648 ENSG00000123268 ENSG00000204217 PMC7374719__F3 Advances in basic research that could lead to the generation of novel therapeutics ENSG00000105397 ENSG00000168610 ENSG00000086730 ENSG00000196712 PMC9355528__F4 Targets and treatments affect oxidative stress in gliomas: An overview of molecular mechanisms ENSG00000149311 ENSG00000198793 ENSG00000164690 ENSG00000163501 PMC4146646__F11 Schematic summary indicating the mechanism by which Cdt, specifically CdtB, affects the PI-3K signaling pathway and the production of pro-inflammatory cytokines ENSG00000172936 ENSG00000175104 PMC8257864__F7 Comprehensive analysis of DNA methylation and gene expression profiles in gestational diabetes mellitus ENSG00000188641 ENSG00000065833 ENSG00000011566 ENSG00000149084 ENSG00000158615 ENSG00000138166 ENSG00000137198 ENSG00000152952 PMC8045357__F1 SOCS protein structure ENSG00000274211 ENSG00000120833 ENSG00000172005 ENSG00000175104 ENSG00000180008 ENSG00000276561 PMC9479325__F5 Integrated analysis of immune parameters, miRNA-mRNA interaction, and immune genes expression in the liver of rainbow trout following infectious hematopoietic necrosis virus infection ENSG00000172936 ENSG00000215301 ENSG00000090659 PMC7210388__F1 GPR50 Promotes Hepatocellular Carcinoma Progression via the Notch Signaling Pathway through Direct Interaction with ADAM17 ENSG00000283780 ENSG00000102195 ENSG00000185591 PMC7659026__F2 HMGB1 participates in inflammatory processes ENSG00000107562 ENSG00000189403 ENSG00000121966 PMC6827427__F6 TGF-beta signaling pathway annotated by ceRNA pairs of CDKN2B (p15) ENSG00000170365 ENSG00000137834 ENSG00000198742 ENSG00000185591 ENSG00000067900 ENSG00000164093 ENSG00000205250 PMC6779479__F12 Proposed disease model of LMNA-DCM ENSG00000160789 ENSG00000198626 ENSG00000145349 PMC6330352__F3 Cartoon depiction illustrating potential saturated free-fatty acid mechanisms that may underlie arrhythmogenic events ENSG00000148798 ENSG00000125538 ENSG00000136869 PMC6350191__F6 Mitogen-activated protein kinase signaling pathway ENSG00000087095 ENSG00000172680 ENSG00000147862 ENSG00000138798 ENSG00000167074 ENSG00000130159 ENSG00000127191 ENSG00000081189 ENSG00000170458 ENSG00000149269 ENSG00000177606 ENSG00000146648 ENSG00000196712 ENSG00000026103 PMC6330352__F2 Cardiac and macrophage inflammatory pathways ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC3925034__F1 Schematic depiction of some of the Ca2+ channels, pumps and exchangers involved in Ca2+signalling in mammalian cells ENSG00000167323 ENSG00000293604 ENSG00000156026 PMC11911377__F1 CGAS-STING signaling pathway and its role in innate immunity ENSG00000169245 ENSG00000183735 ENSG00000115415 ENSG00000142166 PMC3381865__F6 Proposed model for the role of the IGF-1R/NFKB signaling pathway in regulating the caspase-3 differentiation initiation signal ENSG00000002330 ENSG00000140443 PMC11911377__F5 HBV evasion and activation of the cGAS-STING pathway ENSG00000182481 ENSG00000292096 ENSG00000164430 PMC6386986__F5 CRPC development ENSG00000075223 ENSG00000129514 ENSG00000171791 PMC6178121__F2 Pathway analysis shows apolipoprotein E along with its respective interactions in Parkinson’s disease and schizophrenia pathway ENSG00000142192 ENSG00000108179 ENSG00000130164 ENSG00000179091 ENSG00000157193 ENSG00000204843 ENSG00000175899 ENSG00000106688 ENSG00000171791 ENSG00000164305 ENSG00000135250 PMC9322175__F2 Critical Roles of NFKB Signaling Molecules in Bone Metabolism Revealed by Genetic Mutations in Osteopetrosis ENSG00000104856 ENSG00000109320 PMC2423668__F1 Two branches of TLR downstream signaling ENSG00000172936 ENSG00000175104 PMC6745179__F7 CD28 KO reverses lung blast injury by the PI3K/Akt/FoxO1 signaling pathway ENSG00000177575 ENSG00000125538 ENSG00000026508 PMC10451380__F1 Scheme of the NRF2 signaling pathway ENSG00000175793 ENSG00000178573 ENSG00000100387 ENSG00000079999 PMC8533980__F5 CX-5461 Treatment Leads to Cytosolic DNA-Mediated STING Activation in Ovarian Cancer ENSG00000183735 ENSG00000164430 PMC374303__F8 The multiple mechanisms by which HSV-1 blocks cellular IFN-based defense systems ENSG00000067066 ENSG00000144895 ENSG00000115415 ENSG00000140464 PMC5533325__F5 Dietary lipids on the hepatopancreas transcriptome of Chinese mitten crab (Eriocheir sinensis) ENSG00000239732 ENSG00000170458 ENSG00000136869 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000164342 ENSG00000143387 PMC7086357__F8 Proposed model depicting the molecular mechanism by which Serelaxin activates Notch signaling pathway to inhibit TGFBeta-induced SMAD2/3 phosphorylation to restore the RXFP1 expression via histone modifications ENSG00000105329 PMC6365411__F1 A) Experimental design depicting the sampling time points represented as days post hatching (dph) during the different gonad developmental stages covered by the study ENSG00000184254 ENSG00000138207 ENSG00000128918 ENSG00000205221 PMC9265711__F1 LIM Kinases, Promising but Reluctant Therapeutic Targets: Chemistry and Preclinical Validation In Vivo ENSG00000106683 ENSG00000070831 ENSG00000163914 ENSG00000182541 PMC5321852__F4 Hypothetical TRPC4- / TRPC6-mediated signaling pathway downstream of TGFB1 in InMyoFib cells ENSG00000133107 ENSG00000170558 ENSG00000137672 ENSG00000108821 PMC9619486__F1 In silico investigation of the role of vitamins in cancer therapy through inhibition of MCM7 oncoprotein ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000166508 ENSG00000093009 PMC5533325__F6 Dietary lipids on the hepatopancreas transcriptome of Chinese mitten crab (Eriocheir sinensis) ENSG00000111537 ENSG00000137193 PMC5891947__F1 Potential LMTK2-related neurodegenerative mechanisms in Alzheimer’s disease ENSG00000164715 PMC10311566__F1 Recent progress of peptide regulators for the Wnt/Beta-catenin signaling pathway ENSG00000152266 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000133067 ENSG00000168036 PMC8310855__F3 Cannabinoids in the landscape of cancer ENSG00000187688 ENSG00000128272 ENSG00000002330 ENSG00000101255 ENSG00000176046 ENSG00000196689 PMC8507398__F9 Molecular biology of autoinflammatory diseases ENSG00000167207 ENSG00000137275 ENSG00000102871 ENSG00000150455 ENSG00000154124 ENSG00000127191 ENSG00000106100 ENSG00000082512 ENSG00000157625 ENSG00000172936 ENSG00000083799 ENSG00000175104 ENSG00000184216 PMC8564564__F4 Unfolding the role of autophagy in the cancer metabolism ENSG00000198382 ENSG00000198793 PMC9687868__F3 Osteoglycin: An ECM Factor Regulating Fibrosis and Tumorigenesis ENSG00000186575 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC9687868__F2 Osteoglycin: An ECM Factor Regulating Fibrosis and Tumorigenesis ENSG00000168036 ENSG00000146648 PMC8195994__F7 Liver Proteome Profile of Growth Restricted and Appropriately Grown Newborn Wistar Rats Associated With Maternal Undernutrition ENSG00000169047 ENSG00000171388 ENSG00000026103 PMC9585282__F5 Transcriptomic and metabolic analyses reveal the potential mechanism of increasing steroidal alkaloids in Fritillaria hupehensis through intercropping with Magnolia officinalis ENSG00000105722 ENSG00000111837 PMC3187934__F2 Phosphorylation pathways adapted from KEGG (50)(51) ENSG00000169047 ENSG00000198793 ENSG00000140443 PMC4111999__F1 Schematic showing the possible integration of emerging, mass spectrometry-based technologies into the untargeted metabolomic pipeline PMC2491704__F3 Recycling pathway of acetylcholine (ACh) synthesis, release, action and breakdown at a cholinergic nerve terminal ENSG00000114200 ENSG00000087085 PMC6987193__F7 Schematic model based on our results showing the role of E2 in DCIS metastasis to IDC ENSG00000278718 ENSG00000149968 ENSG00000125538 ENSG00000172936 ENSG00000184216 PMC9289374__F1 Gene expression profile of epithelial–mesenchymal transition in tumours of patients with nonsmall cell lung cancer: the influence of COPD ENSG00000169554 ENSG00000124216 ENSG00000122691 ENSG00000170558 ENSG00000100985 PMC7287184__F5 Kyoto Encyclopedia of Genes and Genomes (KEGG)-enriched pathways and related genes ENSG00000175793 ENSG00000120889 ENSG00000277273 ENSG00000145386 ENSG00000166851 ENSG00000117399 ENSG00000080546 ENSG00000093009 ENSG00000183765 ENSG00000206075 ENSG00000094804 ENSG00000171848 ENSG00000123374 ENSG00000112378 ENSG00000075218 ENSG00000115107 ENSG00000112742 PMC4031942__F13 Anti-inflammatory mechanism of C3G is associated with upregulation of the LXRAlpha-ABCG1 pathway which results in disrupting lipid rafts by depleting cholesterol, thereby suppressing the TLR4-mediated NFKB and IRF3 signaling pathways induced by LPS ENSG00000172936 ENSG00000136869 ENSG00000160179 PMC3294670__F7 Mechanisms of control of Listeria entry by the type IA PI 3-kinase signaling pathway ENSG00000070190 ENSG00000198793 ENSG00000133789 ENSG00000165527 ENSG00000108774 PMC8398409__F6 Reactive Oxygen Species in Host Plant Are Required for an Early Defense Response against Attack of Stagonospora nodorum Berk. Necrotrophic Effectors SnTox ENSG00000103460 ENSG00000105227 PMC11746911__F1 Canonical and non-canonical Smad signaling pathways induced by TGFB ENSG00000070831 PMC4657124__F1 Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC9596750__F1 Targeting the inflammasome in Parkinson’s disease ENSG00000162711 ENSG00000134982 ENSG00000265972 PMC7919800__F1 Insulin-like growth factor (IGF)/IGF-1R signaling pathway in the development of liver disease ENSG00000140443 PMC11746911__F3 Wnt/Beta-catenin and NFKB signaling pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000172936 ENSG00000136869 ENSG00000096717 PMC7589301__F1 The possible molecular mechanism of amantadine’s antidepressant effects at the level of dopaminergic and glutamatergic transmission PMC11746911__F2 VEGF signaling pathway ENSG00000198793 ENSG00000184371 ENSG00000168036 ENSG00000160293 PMC4859887__F2 RTKs mediate DDR through canonical AKT and RAS pathways ENSG00000143799 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000002330 PMC9266551__F3 Gal-3BP in Viral Infections: An Emerging Role in Severe Acute Respiratory Syndrome Coronavirus 2 ENSG00000183735 ENSG00000108679 ENSG00000131323 ENSG00000175104 PMC2952191__F2 mTOR signaling pathway ENSG00000163435 ENSG00000198793 ENSG00000155792 PMC4859887__F3 Some RTKs regulate DDR through specific canonical pathways ENSG00000012061 ENSG00000132646 ENSG00000123374 ENSG00000146648 PMC11699683__F5 Signaling pathways of UA-mediated antioxidative stress and anti-neuroinflammation in neurodegenerative diseases ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000168610 ENSG00000079999 PMC5031174__F7 Diagram showing the regulation of dopaminergic neuronal differentiation of human neural stem cells (hNSCs) ENSG00000169047 ENSG00000198793 PMC6233178__F1 Renal tubular epithelial cells: the neglected mediator of tubulointerstitial fibrosis after injury ENSG00000162711 ENSG00000128272 ENSG00000144895 ENSG00000125538 ENSG00000169136 ENSG00000047936 PMC8634653__F2 Integrins in Gastrointestinal Cancer Metastasis ENSG00000079112 ENSG00000117020 ENSG00000138798 ENSG00000198793 ENSG00000146648 ENSG00000122194 PMC10299014__F1 IL-17RA/RC signalling pathways (Figure adapted from Monin and Gaffen , and from Chung ) ENSG00000175104 ENSG00000127191 ENSG00000163702 PMC11603363__F2 Pyroptosis and the role of immune and non-immune cells in asthma ENSG00000278718 ENSG00000162711 ENSG00000115415 ENSG00000163568 ENSG00000091592 ENSG00000136869 ENSG00000091106 ENSG00000105483 PMC8634653__F1 Integrins in Gastrointestinal Cancer Metastasis ENSG00000168283 ENSG00000070831 ENSG00000163914 PMC11603363__F1 Pyroptosis pathways ENSG00000278718 ENSG00000145649 ENSG00000147697 ENSG00000073605 PMC7672621__F9 Schematic regulatory pathway of linagliptin in OSI-906-induced hepatic steatosis ENSG00000140443 PMC8417734__F2 Secreted Frizzled Related Proteins in Cardiovascular and Metabolic Diseases ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000070831 ENSG00000134982 ENSG00000177606 ENSG00000058091 ENSG00000183579 ENSG00000185483 ENSG00000168036 ENSG00000108375 ENSG00000109670 PMC8417734__F4 Secreted Frizzled Related Proteins in Cardiovascular and Metabolic Diseases ENSG00000154342 ENSG00000087245 ENSG00000138795 ENSG00000174804 ENSG00000168487 ENSG00000168036 ENSG00000106483 ENSG00000171791 ENSG00000104332 ENSG00000277641 ENSG00000132693 ENSG00000125084 ENSG00000120057 ENSG00000163914 ENSG00000100985 ENSG00000168646 ENSG00000155760 ENSG00000084774 PMC9442994__F9 MICAL2 contributes to gastric cancer cell migration via Cdc42-dependent activation of E-cadherin/Beta-catenin signaling pathway ENSG00000070831 ENSG00000168036 ENSG00000133816 PMC3004842__F2 Flux-sum intensity in Z ENSG00000122966 ENSG00000172005 ENSG00000062485 PMC12052642__F1 Schematic view of principal anti-tumor effects of resveratrol on different cancer-related mechanisms ENSG00000168036 ENSG00000168610 PMC12052642__F3 PI3K signaling pathway in cancer onset and progression ENSG00000117020 ENSG00000002330 PMC2213056__F1 AID-initiated SHM pathways ENSG00000130997 ENSG00000095002 PMC12052642__F2 Major signaling pathways regulated by resveratrol ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000168610 ENSG00000079999 PMC11699683__F2 UA in antioxidative stress and anti-inflammation ENSG00000162711 ENSG00000136869 ENSG00000109667 PMC6370283__F1 Exogenous pathway of lipid metabolism.apo B-48 = apolipoprotein B-48, apo C-II = apolipoprotein C-II, TG = triglyceride, apo E = apolipoprotein E, LPL = lipoprotein lipase ENSG00000042832 PMC6437734__F10 VPA impacts the B cell differentiation into plasma cells and in the isotype switch and maturation affinity of immunoglobulins PMC6437734__F12 VPA promotes the generation of Treg cells ENSG00000157557 ENSG00000049768 PMC6097514__F1 Targetable cell survival mechanisms.Notes: Stimulation of the BCR and its co-receptor CD19 results in downstream signaling via the PI3K/AKT/mTOR pathway ENSG00000177455 ENSG00000186716 ENSG00000198793 ENSG00000197943 ENSG00000010671 PMC3431627__F7 Mechanisms of acquired-resistance to vemurafenib ENSG00000157764 ENSG00000140443 PMC3825725__F1 Janus face of cyclophosphamide ENSG00000169245 ENSG00000112576 ENSG00000134574 ENSG00000105397 ENSG00000089127 ENSG00000156587 ENSG00000185201 ENSG00000110057 ENSG00000276561 ENSG00000124762 ENSG00000285069 PMC12098830__F6 Other immune signaling pathways in CVDs ENSG00000183735 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000150457 ENSG00000276561 ENSG00000131023 PMC12098830__F8 Integration of key signaling pathway in CVDs with immune response ENSG00000138798 ENSG00000146648 ENSG00000079999 PMC3880546__F1 Physiological regulation of the mTOR pathway ENSG00000266173 PMC3189939__F3 CAFET Algorithm Reveals Wnt/PCP Signature in Lung Squamous Cell Carcinoma ENSG00000070831 ENSG00000173218 ENSG00000143126 ENSG00000183762 ENSG00000168036 ENSG00000106483 ENSG00000145349 PMC12098830__F4 Innate Immune Signaling pathway in CVDs ENSG00000278718 ENSG00000162711 ENSG00000167207 ENSG00000163568 ENSG00000163565 ENSG00000182326 ENSG00000236625 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000142405 ENSG00000136869 ENSG00000157625 ENSG00000164342 ENSG00000174125 ENSG00000124256 ENSG00000039537 ENSG00000166278 ENSG00000106100 ENSG00000276561 ENSG00000117020 ENSG00000187554 ENSG00000288512 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC9080202__F1 Sestrin2 in cancer: a foe or a friend? ENSG00000177169 PMC5999604__F1 Hedgehog signalling in the tumourigenesis and metastasis of osteosarcoma, and its potential value in the clinical therapy of osteosarcoma ENSG00000144857 ENSG00000128602 PMC5999604__F4 Hedgehog signalling in the tumourigenesis and metastasis of osteosarcoma, and its potential value in the clinical therapy of osteosarcoma ENSG00000125107 ENSG00000149273 PMC5999604__F3 Hedgehog signalling in the tumourigenesis and metastasis of osteosarcoma, and its potential value in the clinical therapy of osteosarcoma ENSG00000160789 ENSG00000137804 ENSG00000157933 ENSG00000117425 ENSG00000143867 ENSG00000150093 ENSG00000087586 ENSG00000253352 ENSG00000112210 ENSG00000106571 ENSG00000144857 ENSG00000166813 ENSG00000139549 ENSG00000164690 ENSG00000128602 ENSG00000163501 PMC5999604__F2 Hedgehog signalling in the tumourigenesis and metastasis of osteosarcoma, and its potential value in the clinical therapy of osteosarcoma ENSG00000106571 ENSG00000117425 ENSG00000144857 ENSG00000166813 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC8616057__F7 MAPK Inhibition Requires Active RAC1 Signaling to Effectively Improve Iodide Uptake by Thyroid Follicular Cells ENSG00000157764 PMC4733614__F4 Signaling Pathway and Dysregulation of PD1 and its Ligands in Lymphoid Malignancies ENSG00000111537 ENSG00000134982 ENSG00000036473 PMC4733614__F3 Signaling Pathway and Dysregulation of PD1 and its Ligands in Lymphoid Malignancies ENSG00000101751 ENSG00000186716 ENSG00000145321 ENSG00000174059 ENSG00000168610 PMC4733614__F2 Signaling Pathway and Dysregulation of PD1 and its Ligands in Lymphoid Malignancies ENSG00000111537 ENSG00000134982 PMC5328971__F3 Gamma-aminobutyric acid signaling pathway ENSG00000151834 ENSG00000102287 ENSG00000128272 ENSG00000145863 ENSG00000102468 ENSG00000115896 ENSG00000284017 PMC4733614__F1 Signaling Pathway and Dysregulation of PD1 and its Ligands in Lymphoid Malignancies ENSG00000213928 ENSG00000186716 ENSG00000131196 PMC5286794__F1 Regulation of key cancer stem cell signaling pathways by epigenetic mechanisms ENSG00000023734 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000074266 ENSG00000114315 ENSG00000178691 PMC6790052__F1 Ciona robusta cardiopharyngeal gene regulatory network and tunicate phylogeny ENSG00000147488 ENSG00000149418 PMC10991369__F6 Comparative transcriptome analysis of Trichoderma reesei reveals different gene regulatory networks induced by synthetic mixtures of glucose and Beta-disaccharide ENSG00000008952 ENSG00000198168 PMC3880546__F2 Pathological regulation of the mTOR pathway in neurological disease ENSG00000266173 PMC3059752__F3 Knowledge-based pathway analysis (Genomatix BiblioSphere Software) indicating the network of high BMI-associated genes ENSG00000175793 ENSG00000178573 ENSG00000186480 ENSG00000124766 ENSG00000100842 ENSG00000121440 ENSG00000284984 PMC5404975__F1 Overview of the core components of canonical Hippo signaling ENSG00000150457 ENSG00000131023 PMC8307462__F1 NMDARs, Coincidence Detectors of Astrocytic and Neuronal Activities ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC5766603__F5 Phenylephrine synthesis ENSG00000155926 ENSG00000148926 ENSG00000171119 PMC5318160__F5 Glucocorticoid-driven network links many of the top-ranked PLSR genes ENSG00000122025 ENSG00000168209 ENSG00000172216 ENSG00000166523 ENSG00000198793 ENSG00000109906 ENSG00000145321 ENSG00000132326 ENSG00000146122 ENSG00000074966 ENSG00000179094 PMC9136176__F3 Therapeutic Effects of Natural Products on Cervical Cancer: Based on Inflammatory Pathways ENSG00000168610 ENSG00000146648 PMC3544293__F2 MTOR signaling pathway ENSG00000169047 ENSG00000198793 ENSG00000164327 ENSG00000146648 PMC6798062__F1 RAS pathway in cancer ENSG00000094631 ENSG00000002330 ENSG00000156299 ENSG00000198793 ENSG00000163914 ENSG00000177606 ENSG00000136997 ENSG00000196712 ENSG00000283100 PMC7084352__F4 Transcriptional and Metabolomic Analysis of L-Arginine/Nitric Oxide Pathway in Inflammatory Bowel Disease and Its Association with Local Inflammatory and Angiogenic Response: Preliminary Findings ENSG00000081181 ENSG00000126457 ENSG00000118520 ENSG00000007171 PMC7676208__F7 Potential mechanisms of inflammation by COLEC12 mediated through TLR4 in osteosarcoma ENSG00000150782 ENSG00000158270 ENSG00000136869 ENSG00000005381 PMC7084352__F3 Alterations in expression of L-arginine/NO pathway enzymes in inflamed and quiescent tissue from patients with Crohn’s disease as compared to normal small bowel tissue derived from patients with ulcerative colitis ENSG00000126457 ENSG00000118520 ENSG00000007171 PMC7084352__F1 Simplified scheme of L-arginine/NO pathway ENSG00000081181 ENSG00000126457 ENSG00000118520 ENSG00000036473 ENSG00000007171 PMC7854359__F4 Conservative route to genome compaction in a miniature annelid ENSG00000070444 ENSG00000198793 ENSG00000136997 ENSG00000116990 ENSG00000150457 ENSG00000131023 PMC3666883__F11 Sonic hedgehog-Dependent Induction of MicroRNA 31 and MicroRNA 150 Regulates Mycobacterium bovis BCG-Driven Toll-Like Receptor 2 Signaling ENSG00000056558 ENSG00000172936 ENSG00000131323 ENSG00000164690 ENSG00000128602 ENSG00000127191 PMC6126377__F2 Schematic diagram illustrates how tilorone and hypoxia may share common mechanisms in the mediation of the preconditioning response ENSG00000183735 ENSG00000164430 ENSG00000187608 ENSG00000115415 ENSG00000185745 PMC5054337__F3 Simplified central carbon and amino acid metabolic network ENSG00000122966 ENSG00000172005 PMC6126377__F1 Oxygen sensing HIF prolyl hydroxylases modulate transcriptional and metabolic adaptive responses ENSG00000128272 ENSG00000101255 PMC10971231__F1 Interplay of signaling pathways: cellular dynamics within the pancreatic ductal adenocarcinoma microenvironment ENSG00000087245 ENSG00000108691 ENSG00000137033 ENSG00000100985 PMC10971231__F2 Pivotal role of the NGF/TrkA signaling pathway in PDAC ENSG00000196689 PMC8705083__F1 Eukaryotic initiation factor 5A (eIF5A1), the molecule, mechanisms and recent insights into the pathophysiological roles ENSG00000095059 ENSG00000288145 ENSG00000129932 PMC5974435__F3 MAPK signaling to the translational machinery ENSG00000142192 ENSG00000157764 ENSG00000284161 ENSG00000155792 PMC11545879__F4 Mechanisms of Tregs in immune checkpoint blockade therapy ENSG00000291603 ENSG00000181847 ENSG00000134982 ENSG00000156127 ENSG00000049768 ENSG00000175104 ENSG00000150637 PMC2809500__F4 Proteins upregulated during time course analysis in lung or bronchoalveolar lavage fluid (BAL) following intra tracheal instillation of 20 μg carbon nanopaticles (CNP) ENSG00000108702 ENSG00000150782 ENSG00000090534 ENSG00000110799 ENSG00000184371 ENSG00000171560 ENSG00000132693 PMC11019719__F2 Exercise induction at expression immediate early gene (c-Fos, ARC, EGR-1) in the hippocampus: a systematic review ENSG00000198576 ENSG00000096717 ENSG00000168610 PMC8037238__F1 Hexosamine Biosynthetic Pathway (HBP) and O-GlcNAc Cycling ENSG00000100522 ENSG00000147162 ENSG00000198408 PMC7539786__F6 Scheme showing the activation of the STING pathway by cytosolic DNA and regulation by metformin ENSG00000183735 ENSG00000164430 PMC5974435__F2 MTOR and MAPK pathways affect the translatome by modulating the expression of specific subsets of mRNAs ENSG00000116001 ENSG00000145604 ENSG00000012048 ENSG00000112576 ENSG00000155506 ENSG00000128272 ENSG00000284161 ENSG00000167658 PMC5974435__F1 MTOR signaling to the translational machinery ENSG00000177058 ENSG00000145979 ENSG00000284161 ENSG00000118515 ENSG00000155792 ENSG00000167658 ENSG00000179632 ENSG00000196712 PMC6605043__F1 Probable mechanisms of the effects produced by lncRNAs on TBI.Notes: There are several lncRNAs that have been reported to play different roles in the process of TBI PMC1197416__F6 Several signaling pathways converge to drive actin polarization ENSG00000070831 ENSG00000159263 ENSG00000112246 PMC11124330__F17 This study ENSG00000143546 ENSG00000163220 ENSG00000163734 ENSG00000172936 ENSG00000136869 PMC11201820__F2 Interaction between activated ECs and pericytes/vascular smooth-muscle cells (vSMCs) and their targeted inhibitors in red ENSG00000138798 ENSG00000198793 ENSG00000112715 ENSG00000146648 PMC11201820__F1 Relevant pathways and their targeted inhibitors (in red) for the EC ENSG00000138798 ENSG00000198793 ENSG00000112715 ENSG00000154188 ENSG00000146648 PMC11668352__F7 Endoplasmic Reticulum Stress Induces ROS Production and Activates NLRP3 Inflammasome Via the PERK-CHOP Signaling Pathway in Dry Eye Disease ENSG00000162711 ENSG00000128272 ENSG00000265972 PMC5524151__F1 BDNF signaling is a balance between proBDNF/p75NTR and BDNF in glial cells or inhibit phosphorylation of FL-TrkB thereby preventing stimulation of survival, growth, and neuroplasticity ENSG00000122194 PMC11545879__F2 Various genes expressed by Tregs and their surface molecules ENSG00000108702 ENSG00000169245 ENSG00000186810 ENSG00000102962 ENSG00000179934 ENSG00000089692 ENSG00000181847 ENSG00000198793 ENSG00000138755 ENSG00000102970 ENSG00000049768 PMC5545931__F6 PSMA redirects cell survival signaling from the MAPK to the PI3K-AKT pathways to promote the progression of prostate cancer ENSG00000140443 PMC6270946__F3A Profiling of Concanavalin A-Binding Glycoproteins in Human Hepatic Stellate Cells Activated with Transforming Growth FactorB1 ENSG00000053501 ENSG00000128272 ENSG00000100387 ENSG00000113558 ENSG00000198168 ENSG00000135506 PMC6358904__F4 Graphical model of IL-1B activation of signaling pathways leading to acquisition of resistance to cisplatin in breast cancer cells ENSG00000149311 ENSG00000125538 ENSG00000168036 ENSG00000146648 PMC7532081__F6 Diagram illustrates the hypothesis that TP53INP2 modulates cell migration, invasion, and EMT via the GSK-3B/Beta-catenin/Snail1 pathway in bladder cancer.Abbreviation: EMT, epithelial-to-mesenchymal transition ENSG00000168036 ENSG00000078804 PMC4762928__F1 Glucose and glutamine metabolism in cancer cells ENSG00000115419 PMC8671998__F3 Immunogenic ferroptosis and where to find it? ENSG00000150782 ENSG00000239732 ENSG00000125538 ENSG00000189403 ENSG00000136869 PMC8699888__F1 Cellular Senescence in Adrenocortical Biology and Its Disorders ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC5393957__F2 Molecular genetics of osteosarcoma ENSG00000131473 ENSG00000186575 ENSG00000198793 ENSG00000112561 ENSG00000169710 ENSG00000196712 PMC9023794__F2 Programmed Cell Death-Dependent Host Defense in Ocular Herpes Simplex Virus Infection ENSG00000124256 ENSG00000137275 ENSG00000102871 ENSG00000082512 ENSG00000166278 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC5370073__F1 Impact of CTLA-4 Ig versus anti-CD28 domain Abs on alloreactive T cell responses ENSG00000134982 PMC11064142__F10 TLR signalling leads to apoptosis in tumour cells ENSG00000213928 ENSG00000102871 ENSG00000168040 ENSG00000150455 ENSG00000142166 ENSG00000105397 ENSG00000115415 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC8181424__F1 Exercise Factors Released by the Liver, Muscle, and Bones Have Promising Therapeutic Potential for Stroke ENSG00000171720 ENSG00000196591 ENSG00000096717 ENSG00000151025 PMC3909253__F9 Bacteria Induce Prolonged PMN Survival via a Phosphatidylcholine-Specific Phospholipase C- and Protein Kinase C-Dependent Mechanism ENSG00000174125 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC12028518__F5 Expression of the GNPDA1 signaling pathway in breast cancer (MetaCore) ENSG00000149311 ENSG00000175054 ENSG00000070831 ENSG00000051180 ENSG00000095002 ENSG00000139618 PMC11940432__F2 Intracellular signaling pathways of LGR4 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000183579 ENSG00000168036 ENSG00000164093 PMC3891116__F2 Essential cell signaling pathways for prostate cancer (PCa) development and crosstalks between themThe interaction of circulating androgens (T/DHT) with AR is critical for PCa growth ENSG00000138798 ENSG00000150907 ENSG00000277897 ENSG00000168610 ENSG00000146648 PMC8126603__F2 Innate immune and inflammatory responses to SARS-CoV-2: Implications for COVID-19 ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000101146 ENSG00000115415 ENSG00000110713 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC12219279__F5 Exercise ameliorates nonalcoholic fatty liver disease by reducing the IGFBP5 to IGF1 ratio to activate AMPK pathway ENSG00000169047 ENSG00000115461 ENSG00000140443 PMC9608511__F4 Current insights into the regulation of programmed cell death by TP53 mutation in cancer ENSG00000168003 ENSG00000151012 ENSG00000196839 ENSG00000167468 PMC9608511__F7 Current insights into the regulation of programmed cell death by TP53 mutation in cancer ENSG00000002330 ENSG00000026103 PMC4631973__F1 PI3K/PTEN/Akt/mTOR-cascade (Modified according to Cingarlini et al and McCubrey et al) ENSG00000169047 ENSG00000155792 ENSG00000167965 PMC9299105__F2 Dengue Infection - Recent Advances in Disease Pathogenesis in the Era of COVID-19 ENSG00000244731 ENSG00000182326 ENSG00000236625 PMC4747727__F3 Proteomics analysis of exosomes from EBV-driven LCLs compared with exosomes from CD40L-stimulated B cells shows “immune system process” as the most represented pathway, and an enrichment in “integrin-mediated signaling” and “cell adhesion” terms ENSG00000171403 ENSG00000081237 ENSG00000291971 ENSG00000197471 ENSG00000105699 ENSG00000127022 ENSG00000010278 ENSG00000104921 ENSG00000291973 ENSG00000180210 ENSG00000196576 ENSG00000117054 ENSG00000224320 ENSG00000117091 ENSG00000154122 ENSG00000185201 ENSG00000010810 ENSG00000277263 ENSG00000154310 ENSG00000161929 PMC3154047__F1 Activation of mammalian target of rapamycin complex 1 (mTORC1) ENSG00000198793 ENSG00000167965 PMC8868482__F1 Involvement of Inflammasome Components in Kidney Disease ENSG00000162711 ENSG00000088888 ENSG00000265972 ENSG00000100219 PMC9299105__F4 Dengue Infection - Recent Advances in Disease Pathogenesis in the Era of COVID-19 ENSG00000162711 ENSG00000150782 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 ENSG00000115594 PMC4230700__F3 Disseminated cancer cell dormancy: an awakening field ENSG00000167601 ENSG00000112576 ENSG00000170365 ENSG00000105329 ENSG00000135446 ENSG00000146648 ENSG00000204217 PMC9023794__F1 Programmed Cell Death-Dependent Host Defense in Ocular Herpes Simplex Virus Infection ENSG00000100290 ENSG00000002330 ENSG00000213658 ENSG00000144895 ENSG00000168040 ENSG00000135116 ENSG00000104081 PMC6823288__F6 Significant KEGG pathways enrichment of DEGs ENSG00000168209 ENSG00000173992 ENSG00000038427 ENSG00000123838 ENSG00000007908 ENSG00000151617 ENSG00000162772 ENSG00000155657 ENSG00000138356 PMC7304108__F8 Proposed model by which hsa_circRNA_102610 promotes growth and transforming growth factorB1-induced epithelial-mesenchymal transition of intestinal epithelial cells by sponging hsa-miR-130a-3p ENSG00000170558 PMC3696739__F3 Parathyroid Hormone-Related Protein Specifies the Mammary Mesenchyme and Regulates Embryonic Mammary Development ENSG00000107779 ENSG00000087245 ENSG00000120149 ENSG00000168036 PMC11735109__F11 Schematic representation showing a possible mechanism of YAP1-driven induction of immunosuppression in UCB mediated by the IL-6/STAT3 pathway ENSG00000168610 PMC1176393__F2 Regulatory network of stress responses to drought, salt, and cold: specificity and cross-talk ENSG00000110395 ENSG00000115904 ENSG00000100485 PMC9561407__F3 Iron metabolism, ferroptosis, and lncRNA in cancer: knowns and unknowns ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000104064 PMC6311104__F2 Steps in miRNA biogenesis ENSG00000092847 ENSG00000128191 ENSG00000113360 ENSG00000134698 ENSG00000123908 PMC4180403__F1 Therapeutic Considerations in Treating HER2-Positive Metastatic Breast Cancer ENSG00000157764 ENSG00000198793 PMC9629604__F1 IFN activation of the JAK-STAT signaling pathway ENSG00000111537 ENSG00000115415 ENSG00000133116 PMC11200741__F3 Outline of the Hippo signalling pathway ENSG00000136997 ENSG00000150457 ENSG00000131023 PMC10896604__F4 Metabolic pathways involved in rectal cancer radioresistance, including significantly upregulated (marked in red) and downregulated (marked in green) abundances of proteins and metabolites in poor responders tumor tissues ENSG00000284320 ENSG00000092621 ENSG00000115419 ENSG00000159399 PMC11200741__F1 Canonical pathway (WNT/Beta-catenin pathway) ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3717794__F2 Interfaces Between Signal Transduction Pathways: IGF-1/mTor, p53 and the Parkinson Disease Pathway ENSG00000135423 ENSG00000078237 PMC3717794__F1 Interfaces Between Signal Transduction Pathways: IGF-1/mTor, p53 and the Parkinson Disease Pathway PMC9141140__F4 Rare Variant Analysis and Molecular Dynamics Simulation in Alzheimer’s Disease Identifies Exonic Variants in FLG ENSG00000142192 ENSG00000143631 PMC11580016__F2 The sources of AHR ligands ENSG00000106546 PMC11580016__F1 AHR signaling ENSG00000291971 ENSG00000106546 PMC5674068__F10 The breast tumor vs mammary gland serial-omics experiment ENSG00000042832 ENSG00000198793 ENSG00000173599 ENSG00000169710 ENSG00000164327 PMC3136711__F2 Qu on cell cycle ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC2096753__F1 Summary of purinergic pathways involved in microglial response ENSG00000125538 ENSG00000122194 PMC12102305__F9 Graphical abstract shows the unique characteristics of neuron damage in the SN of PD mice due to oligodendrocyte and astrocyte crosstalk ENSG00000066468 ENSG00000185883 ENSG00000151012 ENSG00000167468 ENSG00000189043 ENSG00000102678 ENSG00000077782 PMC7347012__F6 Development of ocular surface ectodermal cell lineages from human induced pluripotent stem cells PMC4401222__F1 TLR4 signaling pathway and its relation with atherosclerosis ENSG00000172936 ENSG00000136869 PMC5961736__F2 Illustration of JAK/STAT signaling pathway that inspires effective therapeutic targets in lymphoma ENSG00000291971 ENSG00000198793 ENSG00000136997 ENSG00000171791 PMC7185085__F1 Exogenous LPS directly leads to an increase in the production of white adhesion molecules and other cytokines such as ICAM-1 and vWF ENSG00000110799 ENSG00000125538 ENSG00000136869 ENSG00000178568 PMC5961736__F1 Illustration of cross-communication network of BCR, PI3K, and NFKB signaling pathways that harbor effective therapeutic targets in lymphoma ENSG00000104856 ENSG00000186716 ENSG00000198793 ENSG00000173039 ENSG00000172936 ENSG00000010671 ENSG00000198286 PMC5961736__F4 PD-1/PD-Ls signaling pathway that acts as effective therapeutic targets in lymphoma ENSG00000291603 ENSG00000134982 ENSG00000198793 PMC3167192__F1 Molecular basics of tumor angiogenesis ENSG00000196411 ENSG00000007171 PMC5961736__F3 Apoptosis signaling pathway that contains effective therapeutic targets in lymphoma ENSG00000149311 ENSG00000175054 ENSG00000102871 ENSG00000136997 ENSG00000171791 ENSG00000168040 PMC3639415__F8 The regulation and function of MYC in the androgen signaling pathway in molecular apocrine breast cancers ENSG00000136997 ENSG00000129514 PMC4571974__F9 TRAF6 regulation by arginine methylation ENSG00000070495 ENSG00000126457 ENSG00000175104 ENSG00000090376 PMC6502998__F2 Marè et al ENSG00000062485 ENSG00000084774 PMC6156235__F6 A schematic illustration of how dipalmitoylphosphatidic acid (DPPA) might inhibit angiogenesis in breast cancer ENSG00000019991 PMC8389681__F4 Enzymes in the Cholesterol Synthesis Pathway: Interactomics in the Cancer Context ENSG00000110921 ENSG00000101751 ENSG00000105835 ENSG00000168000 ENSG00000291729 ENSG00000165280 ENSG00000170242 ENSG00000167508 ENSG00000107175 ENSG00000095380 ENSG00000125249 ENSG00000138674 ENSG00000150991 ENSG00000100209 ENSG00000004897 ENSG00000083799 ENSG00000178691 ENSG00000116761 PMC8389681__F6 Enzymes in the Cholesterol Synthesis Pathway: Interactomics in the Cancer Context ENSG00000103266 ENSG00000136878 ENSG00000001630 ENSG00000172893 ENSG00000078747 ENSG00000159461 ENSG00000198961 ENSG00000104549 ENSG00000287542 ENSG00000154310 ENSG00000083799 ENSG00000162298 PMC10222229__F2 Roles of protein phosphatases in liver regeneration ENSG00000168610 PMC4524427__F1 Insulin signaling network that links nutrition to growth and size PMC4105198__F8 B3 integrin-KRAS-RalB complex drives tumor stemness and resistance to EGFR inhibition ENSG00000183735 ENSG00000144118 ENSG00000146648 PMC8017223__F1 IL-23 receptor polymorphism associated disorders ENSG00000138378 ENSG00000105397 ENSG00000168610 PMC3610211__F1 TSC/mTORC1 signaling pathway at the neuronal synapse ENSG00000174013 ENSG00000198793 ENSG00000196712 PMC8861264__F8 Haploinsufficiency of Tmem43 in cardiac myocytes activates the DNA damage response pathway leading to a late-onset senescence-associated pro-fibrotic cardiomyopathy ENSG00000149311 ENSG00000160789 ENSG00000164430 ENSG00000105329 ENSG00000038427 ENSG00000130513 PMC5994257__F11 Schema of signaling pathway involved in HSP60-mediated NLRP3 inflammasome activation and subsequent IL-1B production ENSG00000162711 ENSG00000125538 ENSG00000136869 ENSG00000115594 PMC7530326__F1 TGFB signaling pathway ENSG00000104899 ENSG00000137834 ENSG00000156574 ENSG00000135414 ENSG00000130283 ENSG00000163217 ENSG00000170365 ENSG00000164404 ENSG00000130385 ENSG00000095739 ENSG00000184344 ENSG00000204217 ENSG00000114739 PMC7530326__F3 Dysregulation of BMP-ALK1-Smad4 signaling in HHTs ENSG00000112715 PMC7530326__F2 Dysregulation of TGFB/BMP signaling in CCM ENSG00000170458 ENSG00000026508 ENSG00000127528 ENSG00000136869 ENSG00000136826 PMC4304911__F3 Regulation of protein synthesis through the mTOR signaling pathway by amino acids and insulin ENSG00000169047 ENSG00000198793 PMC9149051__F2 Figure 2:. Adaptive response programs in tumor cells and in the tumor ecosystem ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000169047 ENSG00000198793 ENSG00000123374 ENSG00000051180 ENSG00000146648 PMC12116488__F2 Testosterone-AR signaling pathway in HCC immunotherapy ENSG00000184979 ENSG00000111537 ENSG00000168036 ENSG00000049768 PMC11276060__F3 LncRNAs in autophagy, apoptosis response, and inflammation of cells to bacterial invasion ENSG00000162711 ENSG00000138378 ENSG00000226275 ENSG00000198793 ENSG00000172936 PMC12116488__F1 Molecular mechanisms of estrogen signaling in hepatocellular carcinoma (HCC) progression and immune modulation ENSG00000168610 PMC11889322__F3 Diagram depicts the Aryl hydrocarbon receptor (AhR) signaling pathway, starting with the cytoplasmic retention of inactive AhR in a complex with heat shock protein 90 (HSP90), X-associated protein 2 (XAP2), and p23 ENSG00000171759 ENSG00000140465 ENSG00000106546 PMC7188081__F1 Advanced Glycation End Products: Building on the Concept of the “Common Soil” in Metabolic Disease ENSG00000169047 PMC8228386__F2 FGF15 in Hepatic Surgery in the Presence of Tumorigenesis: Dr. Jekyll or Mr. Hyde? ENSG00000160867 ENSG00000168610 PMC8184591__F1 Network of Paf1C Functions ENSG00000101751 ENSG00000188895 ENSG00000006712 ENSG00000174579 ENSG00000166169 ENSG00000128908 PMC4738716__F5 Network of TREM1 and PTGS2 (COX-2) upstream regulators and their target molecules, evaluated in the peripheral blood cells of breast cancer patients compared with healthy donors (Ingenuity Pathway Analysis) ENSG00000145824 ENSG00000172216 ENSG00000109321 ENSG00000163739 ENSG00000104320 ENSG00000122877 ENSG00000091409 ENSG00000073756 ENSG00000121966 PMC9140735__F8 STIM1–Orai1 Interaction Exacerbates LPS-Induced Inflammation and Endoplasmic Reticulum Stress in Bovine Hepatocytes through Store-Operated Calcium Entry ENSG00000167323 ENSG00000293604 PMC2841057__F1 Aldosterone: Role in the Cardiometabolic Syndrome and Resistant Hypertension ENSG00000175054 ENSG00000169047 PMC2841057__F4 Aldosterone: Role in the Cardiometabolic Syndrome and Resistant Hypertension ENSG00000175054 ENSG00000169047 PMC6314084__F6 Evidence of active A ENSG00000178573 ENSG00000109534 ENSG00000026103 PMC4890635__F3 SOX9 is downstream effector of ERG and AR in TMPRSS2:ERG fusion-positive PCa ENSG00000157554 ENSG00000125398 ENSG00000168036 ENSG00000129514 PMC7362612__F1 Receptor-interacting protein kinase 1 (RIPK1) as a therapeutic target ENSG00000123240 ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000154124 ENSG00000127191 ENSG00000183735 ENSG00000056558 ENSG00000157625 ENSG00000198933 ENSG00000083799 ENSG00000064012 ENSG00000285379 PMC3770140__F2 PHLPP suppresses the PI3K/Akt signalling pathway ENSG00000198793 PMC3382482__F1 GFPT1-mediated MTOR signaling pathway affected by glucose and fructose in a pTr cell line ENSG00000198380 ENSG00000198793 ENSG00000187840 PMC8642801__F1 DR-5 and DLL-4 mAb Functionalized SLNs of Gamma-Secretase Inhibitors- An Approach for TNBC Treatment ENSG00000128917 ENSG00000198435 ENSG00000136997 PMC8657577__F1 Genetic Variants of the NFKB Pathway: Unraveling the Genetic Architecture of Psoriatic Disease ENSG00000141527 ENSG00000173039 ENSG00000162924 ENSG00000028137 PMC3942504__F1 Molecular mechanisms of Bcl-6 expression in T cells ENSG00000138378 ENSG00000111537 ENSG00000115415 ENSG00000150907 ENSG00000040199 ENSG00000168610 PMC9533579__F3 Stem cell secretome as a mechanism for restoring hair loss due to stress, particularly alopecia areata: narrative review ENSG00000149968 ENSG00000168036 ENSG00000111186 PMC9476775__F5 Brusatol: A potential anti-tumor quassinoid from Brucea javanica ENSG00000170558 ENSG00000198793 ENSG00000284099 PMC1449730__F2 F igure 2.— ENSG00000180210 ENSG00000039537 ENSG00000117525 PMC5700013__F2 PCSK9 in neuronal apoptosis ENSG00000132906 ENSG00000171791 ENSG00000164305 ENSG00000169174 PMC8745764__F4 COVID-19: Immunohistochemical Analysis of TGFB Signaling Pathways in Pulmonary Fibrosis ENSG00000130234 PMC8744613__F6 Energy Sensor AMPKA1 Is Critical in Rapamycin-Inhibition of mTORC1-S6K-Induced T-cell Memory ENSG00000177169 ENSG00000150907 PMC11582033__F8 Druggable targets and therapeutic strategies for melanoma treatment ENSG00000157764 ENSG00000163599 ENSG00000198793 PMC11582033__F7 Combination therapy of melanoma using BRAF, MEK, and immune checkpoint inhibitors ENSG00000163599 PMC6206931__F6 Overview of lipid remodeling in yeast during acid adaptation, where heavy arrows indicate enhanced biosynthesis ENSG00000146005 ENSG00000171759 ENSG00000128513 PMC11582033__F5 MAPK/ERK signaling pathway and its role in cancer development ENSG00000117020 ENSG00000157764 ENSG00000291971 ENSG00000120875 ENSG00000135446 ENSG00000168610 PMC9306810__F3 ODORANT1 targets multiple metabolic networks in petunia flowers ENSG00000166278 ENSG00000062485 ENSG00000084774 PMC11582033__F2 BRAF/MAPK pathway ENSG00000019991 ENSG00000150907 ENSG00000198793 PMC8141029__F1 mTORC1 stimulates SAM synthesis ENSG00000154059 PMC11582033__F1 RTK/RAF/MAPK signaling in melanoma and its effects on immune cell activity ENSG00000157764 PMC5380548__F2 Wnt signaling and cellular metabolism in osteoblasts ENSG00000128272 ENSG00000281324 ENSG00000162337 ENSG00000144895 ENSG00000115419 PMC5524462__F2 PD-1 is also expressed on T-cells following TCR engagement and activation ENSG00000134982 ENSG00000156127 ENSG00000198793 PMC8502826__F10 Analysis of the Expression and Prognostic Potential of a Novel Metabolic Regulator ANGPTL8/Betatrophin in Human Cancers ENSG00000104415 ENSG00000112494 ENSG00000165682 ENSG00000163743 ENSG00000109758 ENSG00000158104 ENSG00000229314 ENSG00000245848 ENSG00000138207 ENSG00000288411 ENSG00000130173 ENSG00000173599 ENSG00000084734 ENSG00000132855 ENSG00000074771 PMC3616052__F5 Differentially Expressed Genes during Contrasting Growth Stages of Artemisia annua for Artemisinin Content ENSG00000197429 PMC11524886__F3 Potential mechanisms by which exercise-mediated release of irisin exerts antidepressant effects ENSG00000160097 ENSG00000172936 ENSG00000136869 ENSG00000175567 PMC4637890__F6 IL-6 Inhibits Starvation-induced Autophagy via the STAT3/Bcl-2 Signaling Pathway ENSG00000126775 ENSG00000198793 ENSG00000168610 PMC11395143__F2 Nrg1/ErbB signaling ENSG00000065361 ENSG00000198793 PMC8550604__F1 Factor Xa beyond coagulation ENSG00000003436 PMC7518592__F5 Global gene expression profile under low-temperature conditions in the brain of the grass carp (Ctenopharyngodon idellus) ENSG00000110921 ENSG00000112972 ENSG00000172893 ENSG00000113161 ENSG00000104549 ENSG00000120437 ENSG00000167508 PMC10915378__F6 Neurodevelopmental and thalamocortical processes involved in epistasis driving spike‐and‐wave discharge (SWD) phenotypes in mice ENSG00000128951 ENSG00000149269 ENSG00000168036 ENSG00000137822 PMC11045263__F1 Mechanisms underlying enhanced immunotherapy efficacy through exercise ENSG00000169248 ENSG00000186810 ENSG00000138755 ENSG00000104549 PMC4773745__F1 Inhibition of components of the Shh Pathway in cancer ENSG00000136997 ENSG00000164690 PMC9312812__F5 Emerging Link between Tsc1 and FNIP Co-Chaperones of Hsp90 and Cancer ENSG00000101407 ENSG00000198793 ENSG00000052795 ENSG00000155792 ENSG00000217128 ENSG00000167965 PMC7934813__F2 Central role of ACE 2 in SARS-CoV-2 infection and COVID-19 severity ENSG00000175054 ENSG00000130234 ENSG00000184012 PMC4497429__F1 The PI3K/Akt/mTOR signaling pathway and CSC biology ENSG00000119888 ENSG00000164327 ENSG00000118777 PMC9312812__F1 Emerging Link between Tsc1 and FNIP Co-Chaperones of Hsp90 and Cancer ENSG00000052795 ENSG00000217128 PMC3382223__F2 Ingenuity Pathway Analysis of altered expression of proinflammatory genes in normal human melanocytes ENSG00000108691 ENSG00000081041 ENSG00000109320 ENSG00000168811 PMC6135699__F5 Modulating Inflammation through the Negative Regulation of NFKB Signaling ENSG00000172005 ENSG00000056558 ENSG00000173039 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000083799 ENSG00000175104 ENSG00000184216 PMC6139543__F11 Proposed alternative metabolic/antidotal pathway of atRAL in the retina ENSG00000121207 ENSG00000116745 ENSG00000197713 PMC6135699__F3 Modulating Inflammation through the Negative Regulation of NFKB Signaling ENSG00000104856 ENSG00000107562 ENSG00000131323 ENSG00000127191 PMC10875024__F6 CCN3 involvement in cell apoptosis and FGFR2 signaling pathways ENSG00000066468 ENSG00000136999 ENSG00000152192 ENSG00000151615 ENSG00000161642 ENSG00000196396 ENSG00000025293 ENSG00000172530 PMC8971671__F8 CX3CL1 Worsens Cardiorenal Dysfunction and Serves as a Therapeutic Target of Canagliflozin for Cardiorenal Syndrome ENSG00000168329 ENSG00000067900 PMC10875024__F8 Key signaling pathways regulating stem cell pluripotency ENSG00000071564 ENSG00000136603 ENSG00000084093 ENSG00000134982 ENSG00000156574 ENSG00000128342 ENSG00000168610 ENSG00000170571 PMC9120357__F3 Beware of Misdelivery: Multifaceted Role of Retromer Transport in Neurodegenerative Diseases ENSG00000116688 ENSG00000158828 ENSG00000069329 PMC2888634__F4 Drug-induced DNA damage may be repaired by various DNA repair pathways, or apoptosis may be triggered as a result of attempted repair of platinum-induced damage by the Mismatch Repair pathway ENSG00000228716 ENSG00000012061 ENSG00000094631 ENSG00000189283 ENSG00000012048 ENSG00000114388 ENSG00000154920 ENSG00000144554 ENSG00000167325 ENSG00000051180 ENSG00000136936 PMC5577343__F2 Schematic overview of the 57 meta-signature genes, their literature-based localisation and involvement in the mid-secretory phase endometrium ENSG00000165169 ENSG00000081181 ENSG00000284881 ENSG00000196975 ENSG00000138792 ENSG00000197442 ENSG00000106688 ENSG00000138356 ENSG00000274619 ENSG00000105664 ENSG00000125144 ENSG00000143320 ENSG00000163993 ENSG00000146678 ENSG00000196352 ENSG00000172201 ENSG00000182718 ENSG00000189058 ENSG00000142627 ENSG00000137673 ENSG00000197635 ENSG00000221869 ENSG00000106483 ENSG00000116717 ENSG00000169242 ENSG00000166278 ENSG00000124205 ENSG00000211445 ENSG00000118785 ENSG00000134827 ENSG00000106772 ENSG00000164136 ENSG00000148702 ENSG00000123838 ENSG00000127324 ENSG00000136160 ENSG00000150347 ENSG00000115523 ENSG00000123689 PMC5787545__F1 Gut microbes on innate immune receptor ENSG00000167207 ENSG00000096395 ENSG00000157601 ENSG00000214285 ENSG00000136869 ENSG00000091106 ENSG00000112115 PMC6108866__F4 Role of EpCAM in cell signaling ENSG00000138795 ENSG00000187682 ENSG00000281324 ENSG00000119888 ENSG00000134982 ENSG00000155011 ENSG00000173599 ENSG00000168036 PMC6463300__F1 HGF/MET signaling pathway ENSG00000019991 ENSG00000163914 PMC5784884__F5 Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study ENSG00000142192 ENSG00000135218 ENSG00000002330 ENSG00000018510 ENSG00000119537 ENSG00000116906 ENSG00000183484 PMC4202148__F6 Silencing of miRNA-148a by hypermethylation activates the integrin-mediated signaling pathway in nasopharyngeal carcinoma ENSG00000106299 ENSG00000067900 ENSG00000160293 PMC5819907__F1 Calcium signaling pathway, with red font indicating target genes ENSG00000182533 ENSG00000156026 ENSG00000186716 PMC9304552__F3 Metabolic Regulation of Cardiac Regeneration ENSG00000151726 ENSG00000067992 ENSG00000105835 ENSG00000198408 ENSG00000198793 ENSG00000168036 ENSG00000164093 ENSG00000100294 ENSG00000178568 PMC9439853__F4 Exercise-induced modulation of myokine irisin in bone and cartilage tissue—Positive effects on osteoarthritis: A narrative review ENSG00000128272 ENSG00000168610 PMC8236623__F1 Targeting Growth Factor Signaling Pathways in Pancreatic Cancer: Towards Inhibiting Chemoresistance ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8100889__F3 Breast Cancer Therapeutics and Biomarkers: Past, Present, and Future Approaches ENSG00000012048 ENSG00000135446 ENSG00000197429 ENSG00000105810 ENSG00000204520 PMC7865698__F1 Inflammation and cancer connection pathways ENSG00000125538 ENSG00000105656 ENSG00000168610 PMC2476215__F3 Brick by brick: metabolism and tumor cell growth ENSG00000115419 ENSG00000026103 PMC4631974__F2 Activation of PPARG by bioactive lipids can modulate signaling in progressive colorectal cancer ENSG00000074181 ENSG00000136826 PMC6135699__F2 Modulating Inflammation through the Negative Regulation of NFKB Signaling ENSG00000172005 ENSG00000173039 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC8004172__F2 Molecular components of the host contributing to the modulation of the immune response during human metapneumovirus (hMPV) infection ENSG00000183735 ENSG00000089692 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000142089 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC1820751__F3 Ras signaling pathway relays growth signals from activated growth factor receptors to the nucleus ENSG00000033327 ENSG00000196712 ENSG00000062485 PMC5874888__F4 Hypoxia on HIF-1A ENSG00000134086 ENSG00000177189 ENSG00000181788 ENSG00000198793 ENSG00000196365 ENSG00000159399 PMC3382223__F3 Ingenuity Pathway Analysis of altered expression of proinflammatory genes in normal human melanocytes transduced with Ad-Slug ENSG00000095585 ENSG00000275385 ENSG00000101000 ENSG00000115353 ENSG00000276838 PMC8917441__F10 Prediction of the Active Components and Possible Targets of Xanthii Fructus Based on Network Pharmacology for Use in Chronic Rhinosinusitis ENSG00000136997 PMC3996583__F2 Construction of the FB-iPSC-CM regulatory circuit ENSG00000285109 ENSG00000203877 ENSG00000128342 ENSG00000156860 ENSG00000081189 ENSG00000136826 ENSG00000089225 ENSG00000016082 PMC9206264__F1 Investigation of BRCAness associated miRNA-gene axes in breast cancer: cell-free miR-182-5p as a potential expression signature of BRCAness ENSG00000012048 ENSG00000136492 ENSG00000051180 ENSG00000139618 ENSG00000183765 PMC8917441__F11 Prediction of the Active Components and Possible Targets of Xanthii Fructus Based on Network Pharmacology for Use in Chronic Rhinosinusitis ENSG00000170458 ENSG00000168040 ENSG00000150455 ENSG00000127948 PMC11504336__F2 Complex pathological processes during PCO formation under oxidative stress ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9647626__F2 microRNAs associated with the pathogenesis and their role in regulating various signaling pathways during Mycobacterium tuberculosis infection ENSG00000174125 ENSG00000163235 ENSG00000138798 ENSG00000198793 ENSG00000172005 ENSG00000172936 ENSG00000171791 ENSG00000168040 ENSG00000175104 ENSG00000168610 PMC3240703__F2 Glycosylated Synaptomatrix Regulation of Trans-Synaptic Signaling ENSG00000042832 PMC3327812__F7 Protective strategy against hyperinflammatory responses requiring the non-transcriptional actions of GPS2 ENSG00000169047 ENSG00000127191 ENSG00000288325 PMC8712703__F6 Attenuating Effect of Low-Intensity Pulsed Ultrasound on Hypoxia-Induced Rat Chondrocyte Damage in TMJ Osteoarthritis Based on TMT Labeling Quantitative Proteomic Analysis ENSG00000169291 ENSG00000002330 ENSG00000010810 ENSG00000163914 PMC10244910__F10 Neferine attenuates development of testosterone-induced benign prostatic hyperplasia in mice by regulating androgen and TGFB/Smad signaling pathways PMC11504336__F3 Role and mechanism of Grx1 and Grx2 in protection against PCO formation ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000170558 ENSG00000168036 PMC7312739__F2 Combinatorial treatment approach of Nuclear factorKB (NFKB) inhibition and immune checkpoint blockade ENSG00000111537 ENSG00000146648 PMC9670202__F2 When the clock ticks wrong with COVID‐19 ENSG00000130234 ENSG00000184012 PMC7312739__F1 Transcriptional and posttranslational regulation of programmed-death ligand 1 (PD-L1) by Nuclear factorKB (NFKB) ENSG00000111537 ENSG00000146648 PMC11941770__F1 Differentiation of T helper (Th17) Cells and Interleukin-17A (IL-17A) signaling pathway ENSG00000134982 ENSG00000082512 ENSG00000175104 ENSG00000127191 ENSG00000168610 PMC9478335__F3 Adipose tissue macrophage in obesity-associated metabolic diseases ENSG00000125538 ENSG00000169047 PMC8110445__F9 拟康氏木霉胞外多糖联合奥沙利铂可体外协同抑制结直肠癌细胞的增殖 ENSG00000177455 ENSG00000002330 ENSG00000108821 ENSG00000185010 PMC9001662__F8 In DR, increased levels of LPS activates the inflammasome in typical and atypical forms ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC5842119__F1 NAD+ intermediates: The biology and therapeutic potential of NMN and NR ENSG00000143799 ENSG00000187531 ENSG00000105835 ENSG00000291803 ENSG00000278488 ENSG00000077463 ENSG00000142082 ENSG00000283100 ENSG00000157064 ENSG00000124523 ENSG00000173614 ENSG00000096717 ENSG00000089163 PMC8119568__F1 microRNAs: New-Age Panacea in Cancer Therapeutics ENSG00000128191 ENSG00000113360 ENSG00000132341 PMC4041276__F8 Signaling pathways mediating DON-induced RSR, including the MAPK (A, blue), NFKB (B, red), AKT and AMPK pathways (C, green) ENSG00000150782 ENSG00000291971 ENSG00000132382 ENSG00000198793 ENSG00000148843 PMC6641538__F2 In eukaryotes, iron acquisition is mediated through metal or metal-siderophore transport ENSG00000066926 PMC12197721__F3 Proteins encoded by multigene family genes (MGFs) involved in the NFKB signaling pathway ENSG00000182481 ENSG00000162711 ENSG00000102753 ENSG00000186432 PMC4342984__F6 The figure shows a scheme illustrating the ASARM-model and the pharmacological effects of SPR4-peptide (bimodal) in HYP and wild type mice ENSG00000118972 ENSG00000152592 PMC12197721__F2 Proteins encoded by multigene family genes (MGFs) involved in the type I IFNs signaling pathway ENSG00000183735 ENSG00000213928 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000276561 ENSG00000142166 PMC3696998__F9 Comparison of CK2 knockout defects and Wnt pathway knockout defects, with a schema to indicate where in the pathway CK2 is believed to act ENSG00000138795 ENSG00000151835 ENSG00000168036 PMC8126961__F3 Is There a Carcinogenic Risk Attached to Vitamin B12 Deficient Diets and What Should We Do About It? Reviewing the Facts ENSG00000228716 PMC3198803__F5 CcpA Ensures Optimal Metabolic Fitness of Streptococcus pneumoniae ENSG00000167207 ENSG00000069482 ENSG00000150787 PMC7930427__F2 Molecular Profiling of Exceptional Responders to Cancer Therapy ENSG00000111358 ENSG00000182578 ENSG00000157764 ENSG00000135100 ENSG00000107625 ENSG00000168591 ENSG00000101224 ENSG00000087460 ENSG00000100385 ENSG00000184675 ENSG00000180447 ENSG00000115524 ENSG00000041982 ENSG00000213658 ENSG00000143768 ENSG00000170458 ENSG00000164161 ENSG00000113296 ENSG00000276870 ENSG00000155760 PMC7775471__F3 NAD+ biosynthesis pathways ENSG00000105835 ENSG00000172890 ENSG00000123572 ENSG00000278488 PMC3198803__F7 CcpA Ensures Optimal Metabolic Fitness of Streptococcus pneumoniae ENSG00000069482 ENSG00000122218 ENSG00000150787 PMC9571692__F1 New Insights into Dietary Pterostilbene: Sources, Metabolism, and Health Promotion Effects ENSG00000181019 PMC8408558__F8 LINC01189-miR-586-ZEB1 feedback loop regulates breast cancer progression through Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000155011 ENSG00000050165 ENSG00000168036 ENSG00000104332 ENSG00000196628 PMC4190587__F3 MicroRNA Regulation of Smooth Muscle Phenotype ENSG00000291971 ENSG00000163914 ENSG00000137193 ENSG00000141052 ENSG00000118971 ENSG00000136826 PMC9693225__F3 Shared Proteome of the Apomictic Fern Dryopteris affinis ssp. affinis and Its Sexual Relative Dryopteris oreades ENSG00000074800 ENSG00000105251 ENSG00000169299 ENSG00000161960 PMC7877184__F8 Morphine-3-glucuronide (M3G) promoting non-small cell lung cancer (NSCLC) immune escape via toll-like receptor 4 (TLR4) and programmed death ligand 1 (PD-L1) ENSG00000170458 ENSG00000172936 ENSG00000136869 PMC3715730__F3 Ingenuity pathway analysis (IPA) of Interferon Signaling Pathway of genes differentially expressed in the bronchial epithelial cells exposed to Alternaria alternata spores ENSG00000213928 ENSG00000111537 ENSG00000115415 ENSG00000004455 ENSG00000033800 ENSG00000185745 ENSG00000125347 PMC4754058__F1 The Notch1 signalling pathway ENSG00000159216 ENSG00000148400 ENSG00000020633 ENSG00000140443 PMC4666670__F4 Transcriptome Analysis of Plant Hormone-Related Tomato (Solanum lycopersicum) Genes in a Sunlight-Type Plant Factory PMC7806419__F7 Schematic of the possible signaling pathway of leukocyte immunoglobulin‐like receptor A3 (LILRA3) ENSG00000276175 ENSG00000276051 PMC4535966__F2 Ingenuity pathway analysis reveals an up-regulation of the NOTCH pathway in LGR5 high SW480 spheres compared to LGR5 low SW480 adherent cells ENSG00000133961 ENSG00000184916 ENSG00000114315 PMC7751369__F10 Protein-protein and gene-gene interaction networks among CCNB2, CCNE2, CDK4, HOMER1, HSP90AA1, NRAS, PPP2CA, PRKAA2 and RAC1 ENSG00000172765 ENSG00000278057 ENSG00000145386 ENSG00000101049 ENSG00000057704 ENSG00000162409 ENSG00000135446 ENSG00000138032 ENSG00000123374 ENSG00000105810 ENSG00000051128 ENSG00000147082 ENSG00000175305 ENSG00000115540 PMC9597306__F5 Recent advances in hydrogels-based osteosarcoma therapy ENSG00000087245 ENSG00000168036 PMC5309296__F5 Phosphoproteomic analysis of SK-ChA-1 cells after ZPCL-PDT ENSG00000177189 ENSG00000175866 ENSG00000140575 ENSG00000169047 ENSG00000115904 ENSG00000162302 ENSG00000130669 ENSG00000089159 PMC9237413__F5 Proteomic Analysis of Hypothalamus and Pituitary Gland in Pre and Postpubertal Brahman Heifers ENSG00000109163 ENSG00000087245 ENSG00000070831 ENSG00000113070 ENSG00000146648 PMC10635949__F5 Effect of BD exposure during adolescence on skeletal muscle metabolism and myokine secretion ENSG00000177169 ENSG00000105550 ENSG00000113140 ENSG00000169047 ENSG00000198793 ENSG00000128342 PMC5166973__F7 Targeting translation initiation bypasses signaling crosstalk mechanisms that maintain high MYC levels in colorectal cancer ENSG00000136997 PMC12232815__F8 Mechanism diagram of BYHWD ENSG00000105835 ENSG00000105953 PMC1951533__F14 Proline-Rich Tyrosine Kinase 2 Mediates Gonadotropin-Releasing Hormone Signaling ENSG00000291971 PMC4339020__F1 TNFA in Cerebral Ischemia: Another Stroke Against You? ENSG00000102871 ENSG00000168040 ENSG00000064012 PMC4645376__F6 Schematic overview of M1 protein-induced IL-8 expression in human keratinocytes ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC3530555__F5 Combined Inhibition of IGF-1R/IR and Src Family Kinases Enhances Antitumor Effects in Prostate Cancer by Decreasing Activated Survival Pathways ENSG00000140443 PMC5711528__F2 Interactome of lupus susceptibility genes, constructed using Strings software (version 9.0; http://string-db.org) via evidence‐based protein–protein interactions ENSG00000187605 ENSG00000172893 ENSG00000161405 ENSG00000198793 ENSG00000072274 ENSG00000164327 ENSG00000141564 ENSG00000143226 ENSG00000185651 ENSG00000168811 ENSG00000057663 ENSG00000236625 ENSG00000168010 ENSG00000168118 ENSG00000129219 ENSG00000153814 ENSG00000166501 ENSG00000198087 ENSG00000157064 ENSG00000145782 ENSG00000076662 ENSG00000120690 ENSG00000169896 ENSG00000030419 ENSG00000140968 ENSG00000139370 ENSG00000115267 ENSG00000153064 ENSG00000152689 ENSG00000116701 ENSG00000171044 ENSG00000276561 ENSG00000136048 ENSG00000117322 ENSG00000213918 ENSG00000138378 ENSG00000105397 ENSG00000072694 ENSG00000118503 PMC5711528__F1 Metabolic pathways controlling activation and lineage specification in the immune system ENSG00000135218 ENSG00000130164 ENSG00000026508 ENSG00000049768 ENSG00000168610 ENSG00000168118 PMC2683667__F4 Induction of IFN-signaling pathways in HCV-infected uPA-SCID mice (A) and patients (B) ENSG00000159128 ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000057593 ENSG00000027697 ENSG00000276561 PMC7871366__F3 Pathway paradigms highlighted by IBD genetics ENSG00000134460 ENSG00000167207 ENSG00000187796 ENSG00000109758 ENSG00000056972 ENSG00000274571 ENSG00000091106 ENSG00000143226 ENSG00000106546 ENSG00000146374 ENSG00000172216 ENSG00000145623 ENSG00000179630 ENSG00000125538 ENSG00000112182 ENSG00000178828 ENSG00000128228 ENSG00000099985 ENSG00000137275 ENSG00000115267 ENSG00000237693 ENSG00000177663 ENSG00000134825 ENSG00000007171 ENSG00000115607 ENSG00000079999 ENSG00000162594 ENSG00000138378 ENSG00000111537 ENSG00000105397 ENSG00000118503 ENSG00000100365 PMC7232014__F1 Autophagy pathway overview, with childhood-onset neurodegenerative diseases affecting the pathway either directly or indirectly highlighted in red font ENSG00000135317 ENSG00000123395 ENSG00000126775 ENSG00000104133 ENSG00000198793 PMC7871366__F2 IBD genes and pathways controlling mucosal immunity ENSG00000134460 ENSG00000167207 ENSG00000187796 ENSG00000109758 ENSG00000056972 ENSG00000106546 ENSG00000146374 ENSG00000153814 ENSG00000138821 ENSG00000084734 ENSG00000179630 ENSG00000166501 ENSG00000163933 ENSG00000112182 ENSG00000178828 ENSG00000115267 ENSG00000133195 ENSG00000119919 ENSG00000134825 ENSG00000073605 ENSG00000095110 ENSG00000007171 ENSG00000079999 ENSG00000137266 ENSG00000162594 ENSG00000113719 ENSG00000138378 ENSG00000111537 ENSG00000118503 ENSG00000113302 ENSG00000115232 ENSG00000100365 PMC3554558__F1 Putative role of VHL-HIF-EPO pathway in RCC progression ENSG00000134086 ENSG00000187266 PMC7090218__F2 Metabolic pathways affecting ferroptosis ENSG00000151012 ENSG00000196839 ENSG00000167468 ENSG00000111684 ENSG00000122873 ENSG00000057663 ENSG00000136381 PMC7611989__F2 TH effects on hepatic autophagy ENSG00000159921 ENSG00000177169 ENSG00000110931 ENSG00000069509 ENSG00000125686 PMC4270942__F7 Estrogen Regulates Energy Metabolic Pathway and Upstream AMPK Kinase and Phosphatase Enzyme Expression in Dorsal Vagal Complex Metabolo-Sensory Neurons during Glucostasis and Hypoglycemia ENSG00000026103 PMC8643130__F2 Gut Microbial-Derived Metabolite Trimethylamine N-Oxide and Atrial Fibrillation: Relationships, Mechanisms, and Therapeutic Strategies ENSG00000162711 ENSG00000150782 ENSG00000125538 PMC9250978__F2 Post-Translational Modifications of Proteins in Cytosolic Nucleic Acid Sensing Signaling Pathways ENSG00000183735 ENSG00000088888 ENSG00000276561 PMC5752873__F1 Wnt signalling pathways and their interactions ENSG00000087095 ENSG00000181788 ENSG00000100592 ENSG00000134982 ENSG00000168036 PMC3407640__F8 Summary of pathways with differentially expressed genes comparing sarcomas to MSC in the current study ENSG00000135446 ENSG00000168036 ENSG00000123374 ENSG00000128602 PMC9250978__F1 Post-Translational Modifications of Proteins in Cytosolic Nucleic Acid Sensing Signaling Pathways ENSG00000183735 ENSG00000164430 ENSG00000163568 ENSG00000163565 PMC8468334__F2 Type I Interferons in COVID-19 Pathogenesis ENSG00000213928 ENSG00000088888 ENSG00000130234 ENSG00000168310 PMC4899583__F3 Schematic shows the potential role of epigenetic mechanism that may be involved in manganese induced chronic neurotoxic effects and in pathology of Parkinson's disease ENSG00000002330 ENSG00000078579 PMC6710795__F8 Proposed model of dovitinib-mediated autophagy and apoptosis with regard to the SHP-1/p-STAT3 pathway in breast cells ENSG00000168610 PMC5826526__F5 Eukaryotic initiation factor 2 (eIF2) signaling pathway ENSG00000180210 ENSG00000163435 ENSG00000171105 ENSG00000128886 ENSG00000144895 ENSG00000100664 PMC12073636__F1 Mechanistic Advances in Hypoglycemic Effects of Natural Polysaccharides: Multi-Target Regulation of Glycometabolism and Gut Microbiota Crosstalk ENSG00000214285 ENSG00000172936 ENSG00000136869 ENSG00000293532 PMC7106760__F8 Schematic illustration of ADAM10 regulates E-cadherin/Beta-catenin signaling pathway which in turn is regulated by miR-122-5p ENSG00000168036 ENSG00000137845 PMC8161379__F2 Ceramide Metabolism and Signaling in the Regulation of Mitophagy and Cancer Therapy ENSG00000177169 ENSG00000223802 ENSG00000083290 ENSG00000158828 PMC8161379__F1 Ceramide Metabolism and Signaling in the Regulation of Mitophagy and Cancer Therapy ENSG00000100422 ENSG00000063176 ENSG00000147869 ENSG00000102172 PMC6992891__F1 Effect and regulation of the NLRP3 inflammasome during renal fibrosis ENSG00000162711 ENSG00000125538 PMC2763495__F1 Metabolic pathways of growth and proliferation ENSG00000122966 ENSG00000136997 PMC7956893__F5 PPI induces protective autophagy through the PI3K/AKT/mTOR pathway by inhibiting AKT (S473), mTOR (S2448), p70S6K (T389), and 4EBP1 (T37/46) and increasing the conversion of LC3I conversion into LC3II ENSG00000138798 ENSG00000198793 ENSG00000164327 PMC2763495__F4 AMPK–p53 pathway in metabolic adaptation ENSG00000078237 ENSG00000284194 PMC6628043__F7 Biofunction analysis of differentially expressed genes from eWAT (A) Biofunction-overlay of the disease and function related to lipolysis in eWAT; (B) the disease and function in response to CLE in eWAT ENSG00000099985 ENSG00000138798 ENSG00000107798 ENSG00000101577 ENSG00000162772 ENSG00000112715 ENSG00000076555 ENSG00000170425 ENSG00000043591 ENSG00000133317 ENSG00000284017 ENSG00000162409 ENSG00000134324 ENSG00000026508 ENSG00000285070 ENSG00000177666 ENSG00000123689 PMC5659363__F2 HCMV-encoded agonists of the NFKB signaling pathway ENSG00000149311 ENSG00000173039 PMC5659363__F1 HCMV-encoded antagonists of the NFKB signalling pathway ENSG00000104856 ENSG00000125538 ENSG00000173039 PMC3322224__F2 cAMP Signaling CascadeLigand binding (represented in this example by PTH, but other ligands and receptors can stimulate cAMP synthesis), activates GsA and stimulates cAMP synthesis by adenylate cyclase ENSG00000152266 ENSG00000113448 PMC7956893__F2 Anticancer molecular mechanisms of PPs ENSG00000128272 ENSG00000144895 ENSG00000198793 PMC7956893__F1 Molecular anticancer mechanisms of PPs ENSG00000168036 ENSG00000168610 ENSG00000026103 PMC7956893__F4 PPs inhibit cancer cell proliferation and induce apoptosis in cancer cells through the NF-kB and MAPK pathways ENSG00000064012 PMC8656686__F2 PCAT6 May Be a Whistler and Checkpoint Target for Precision Therapy in Human Cancers ENSG00000100811 ENSG00000141867 ENSG00000173894 ENSG00000076554 ENSG00000198793 ENSG00000073792 ENSG00000165819 PMC8750516__F1 Targeting the Intrinsic Apoptosis Pathway: A Window of Opportunity for Prostate Cancer ENSG00000100290 ENSG00000002330 ENSG00000135116 ENSG00000104081 PMC5815310__F3 Emerging therapies for idiopathic pulmonary fibrosis, a progressive age-related disease ENSG00000198793 ENSG00000086991 ENSG00000142082 PMC6554677__F1 A model for the regulation of T cell-mediated adaptive immune responses to apoptotic cells ENSG00000134982 PMC2775805__F6 Molecular pathway analysis of genes regulated in the NAc by the HDAC inhibitor MS-275 after chronic social defeat stress ENSG00000084093 ENSG00000163235 ENSG00000163914 ENSG00000146648 PMC8656686__F3 PCAT6 May Be a Whistler and Checkpoint Target for Precision Therapy in Human Cancers ENSG00000122566 ENSG00000141867 ENSG00000173894 ENSG00000076554 ENSG00000145321 ENSG00000168036 ENSG00000126432 PMC9586150__F3 Identification of a miRSNP Regulatory Axis in Abdominal Aortic Aneurysm by a Network and Pathway-Based Integrative Analysis ENSG00000106683 ENSG00000142192 ENSG00000117525 ENSG00000038427 ENSG00000113140 ENSG00000291748 ENSG00000198846 ENSG00000127948 ENSG00000186469 PMC9586150__F6 Identification of a miRSNP Regulatory Axis in Abdominal Aortic Aneurysm by a Network and Pathway-Based Integrative Analysis PMC3724517__F4 Pathway analysis of differentially expressed genes in RAF265 responding versus nonresponding tumors ENSG00000073921 ENSG00000010310 PMC9586150__F8 Identification of a miRSNP Regulatory Axis in Abdominal Aortic Aneurysm by a Network and Pathway-Based Integrative Analysis ENSG00000117525 PMC7935675__F1 After activation of the S subunit protein on the COVID-19 surface by transmembrane protease serine 2 (TMPRSS2), the virus binds to the Angiotensin-converting enzyme 2 (ACE2) receptor and infects the host cell through endocytosis ENSG00000175054 ENSG00000130234 ENSG00000184012 PMC2757293__F2 Innate immune evasion by hepatitis C virus and West Nile virus ENSG00000105397 ENSG00000115415 ENSG00000131323 PMC5036175__F6 Global Phosphoproteomic Analysis Reveals the Involvement of Phosphorylation in Aflatoxins Biosynthesis in the Pathogenic Fungus Aspergillus flavus ENSG00000173599 PMC5272809__F2 New View into the Regulation of Purine Metabolism – The Purinosome ENSG00000128050 PMC5272809__F1 New View into the Regulation of Purine Metabolism – The Purinosome ENSG00000128050 PMC5526580__F1 Impact of MET, IGF-1, IGF1R expression and EGFR mutations on survival of patients with non-small-cell lung cancer ENSG00000019991 ENSG00000198793 ENSG00000168610 ENSG00000146648 ENSG00000140443 PMC8858844__F1 Pyroptosis: A Developing Foreland of Ovarian Cancer Treatment ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000145649 ENSG00000091106 ENSG00000073605 PMC8752857__F4 P38 MAPK pathway in Bactrocera dorsalis ENSG00000197442 ENSG00000135341 PMC6349817__F2 Crosstalk between the PI3K-Akt-mTOR pathway and the Hippo-Yap pathway via SIK2 ENSG00000170145 ENSG00000114019 PMC8052339__F6 Working model of LPS-induced RAGE signaling in sensory neurons innervating the upper airways ENSG00000291971 ENSG00000136869 ENSG00000196689 PMC6406281__F1 Cholesterol homeostasis in normal cells ENSG00000130164 ENSG00000113161 PMC6273859__F7 Possible signaling pathways for tetrandrine-induced apoptosis in NPC-TW 076 human nasopharyngeal carcinoma cells ENSG00000026103 PMC8364652__F5 Dual Role of Reactive Oxygen Species and their Application in Cancer Therapy ENSG00000149311 ENSG00000175054 ENSG00000128272 PMC12135389__F1 CGAS-STING pathway and its cellular and disease functions ENSG00000183735 ENSG00000164430 ENSG00000105397 ENSG00000142166 PMC8364652__F6 Dual Role of Reactive Oxygen Species and their Application in Cancer Therapy ENSG00000149311 ENSG00000012048 ENSG00000101670 ENSG00000181019 ENSG00000266265 ENSG00000079999 PMC7520847__F4 Hedgehog pathway ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC6714236__F7 A schematic model depicting the functions of SNAI3‐AS1 in HCC PMC7520847__F2 Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC4178212__F2 Activation of p53 is predicted to increase the flux through gluconeogenesis ENSG00000173599 ENSG00000124253 PMC7520847__F1 RAS signaling pathway ENSG00000169047 PMC4252580__F2 Aldosterone on insulin sensitivity and secretion ENSG00000291971 ENSG00000169047 ENSG00000118515 ENSG00000130402 ENSG00000119396 ENSG00000140443 PMC8886057__F2 ITCH E3 ubiquitin ligase downregulation compromises hepatic degradation of branched-chain amino acids ENSG00000138029 ENSG00000124370 ENSG00000078070 ENSG00000120437 ENSG00000131844 ENSG00000127884 ENSG00000117054 ENSG00000198754 ENSG00000114054 ENSG00000083720 ENSG00000122971 ENSG00000113790 ENSG00000105552 ENSG00000091140 PMC8894377__F4 Radiotherapy alters expression of molecular targets in prostate cancer in a fractionation- and time-dependent manner ENSG00000104856 ENSG00000291603 ENSG00000102871 ENSG00000138798 ENSG00000173039 ENSG00000168040 ENSG00000150455 ENSG00000226275 ENSG00000244687 ENSG00000163235 ENSG00000157625 ENSG00000172936 ENSG00000175104 ENSG00000198286 PMC6769012__F6 BK ablation attenuates osteoblast bone formation via integrin pathway ENSG00000291971 PMC6871180__F3 Molecular mechanisms of arrhythmogenic cardiomyopathy ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC11566304__F1 Metabolic pathway diagram of hypoxanthine ENSG00000185129 ENSG00000146676 PMC10918650__F1 l-isoleucine biosynthetic pathway in E PMC12103977__F1 Comparative framework for the integrative analysis of cardiovascular phenotypes ENSG00000092054 PMC3916222__F2 Mathematical Modeling of the Phoenix Rising Pathway PMC4209854__F1 EGFR signalling in chronic lung disease ENSG00000160888 ENSG00000163235 ENSG00000113070 ENSG00000138798 PMC3589091__F1 Pathways of PI5P synthesis and turnover ENSG00000112367 ENSG00000124102 ENSG00000115020 PMC9297570__F5 Putting human Tid-1 in context: an insight into its role in the cell and in different disease states ENSG00000154059 ENSG00000146648 PMC4574301__F1 Intestinal epithelial barrier function plays an essential role in maintaining intestinal health ENSG00000269335 PMC11053710__F2 Cross-talk of Dyrk1B in signaling pathways in development and disease ENSG00000117000 ENSG00000106571 ENSG00000198793 ENSG00000128602 ENSG00000105204 PMC7200761__F7 Loss of HAT1 expression confers BRAFV600E inhibitor resistance to melanoma cells by activating MAPK signaling via IGF1R ENSG00000292096 ENSG00000157764 ENSG00000140443 PMC8002730__F3 Core signaling pathways of triple negative breast cancer (TNBC) ENSG00000143195 ENSG00000087245 ENSG00000151882 ENSG00000147649 ENSG00000071073 ENSG00000070831 ENSG00000171791 ENSG00000168610 ENSG00000121966 ENSG00000078804 PMC6797170__F5 Identification of protein changes in the blood plasma of lung cancer patients subjected to chemotherapy using a 2D-DIGE approach ENSG00000204020 ENSG00000167601 ENSG00000132341 PMC3398464__F1 Key branches of the insulin signaling cascade ENSG00000140992 ENSG00000169047 ENSG00000086991 ENSG00000196562 PMC8002730__F5 Common and distinctive core signaling pathways between triple negative breast cancer (TNBC) and non-triple negative breast cancer (non-TNBC) ENSG00000151882 ENSG00000087245 ENSG00000147649 ENSG00000070831 ENSG00000050748 ENSG00000123728 ENSG00000196154 ENSG00000171791 ENSG00000121966 ENSG00000078804 ENSG00000143195 ENSG00000082175 ENSG00000113369 ENSG00000034713 ENSG00000136997 PMC9134593__F1 Application and prospect of targeting innate immune sensors in the treatment of autoimmune diseases ENSG00000174123 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172005 ENSG00000125538 ENSG00000134070 ENSG00000157625 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC8002730__F4 Core signaling pathways of non-triple negative breast cancer (non-TNBC) ENSG00000143195 ENSG00000087245 ENSG00000151882 ENSG00000082175 ENSG00000070831 ENSG00000123728 ENSG00000034713 ENSG00000136997 ENSG00000171791 ENSG00000121966 ENSG00000078804 PMC6797170__F7 Identification of protein changes in the blood plasma of lung cancer patients subjected to chemotherapy using a 2D-DIGE approach ENSG00000003436 ENSG00000110799 ENSG00000088926 ENSG00000122194 ENSG00000178726 ENSG00000185010 ENSG00000180210 ENSG00000126218 ENSG00000101981 ENSG00000117525 ENSG00000117601 ENSG00000057593 ENSG00000175899 ENSG00000198734 ENSG00000276838 PMC9134593__F3 Application and prospect of targeting innate immune sensors in the treatment of autoimmune diseases ENSG00000183735 ENSG00000088888 ENSG00000102871 ENSG00000125538 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000276561 PMC9134593__F2 Application and prospect of targeting innate immune sensors in the treatment of autoimmune diseases ENSG00000278718 ENSG00000162711 ENSG00000174885 ENSG00000091592 ENSG00000274571 ENSG00000091106 ENSG00000276561 ENSG00000276068 ENSG00000088888 ENSG00000281166 ENSG00000142405 ENSG00000157625 ENSG00000131323 PMC4559511__F2 Complement and adaptive immunity ENSG00000111537 ENSG00000134982 ENSG00000186716 ENSG00000117322 PMC8321669__F10 RNA-seq analysis indicates Chemical carcinogenesis inhibition in M3−/− crypts ENSG00000197872 ENSG00000065833 ENSG00000157933 ENSG00000172005 PMC6797170__F4 Identification of protein changes in the blood plasma of lung cancer patients subjected to chemotherapy using a 2D-DIGE approach ENSG00000113905 ENSG00000134982 ENSG00000145192 ENSG00000111837 ENSG00000111816 ENSG00000171560 ENSG00000127948 ENSG00000062485 PMC4559511__F1 Complement cascade ENSG00000166278 PMC11464740__F3 JAK/STAT signaling pathway can be activated or inhibited by inflammatory cytokines to regulate the inflammation of UC ENSG00000111537 ENSG00000105397 PMC6044892__F8 Speculated biosynthesis pathways of glycosylated products elongated on a saccharide primer ENSG00000069482 ENSG00000062485 PMC11894581__F6 PPI networks ENSG00000142798 ENSG00000110799 ENSG00000104332 ENSG00000278270 ENSG00000175029 ENSG00000184500 ENSG00000087128 ENSG00000135443 ENSG00000082196 ENSG00000133110 ENSG00000172216 ENSG00000118785 ENSG00000166482 ENSG00000148702 ENSG00000076716 ENSG00000133961 ENSG00000129128 ENSG00000131196 PMC5877513__F3 An overview of resveratrol-mediated targeting of multiple signaling pathways ENSG00000187531 ENSG00000167772 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000169429 PMC4423606__F4 Inferring alterations in cell-to-cell communication in HER2+ breast cancer using secretome profiling of three cell models PMC5877513__F1 TGF/TGFR signaling axis ENSG00000187531 ENSG00000167772 ENSG00000169429 PMC9297570__F2 Putting human Tid-1 in context: an insight into its role in the cell and in different disease states ENSG00000154059 ENSG00000146648 PMC9297570__F4 Putting human Tid-1 in context: an insight into its role in the cell and in different disease states ENSG00000019991 ENSG00000173757 ENSG00000154059 PMC6307166__F4 CircRNA-miRNA interactions are potentially involved in the initiation and progression of CRC ENSG00000136158 ENSG00000124102 ENSG00000134982 ENSG00000169047 ENSG00000121879 ENSG00000146648 PMC9297570__F3 Putting human Tid-1 in context: an insight into its role in the cell and in different disease states ENSG00000134982 ENSG00000030304 ENSG00000154059 PMC11816596__F1 Canonical Wnt pathway (left): Wnt ligands (such as Wnt1, Wnt2, Wnt3, Wnt3a, and Wnt 8) bind to the frizzled (FZD) receptor and its coreceptors LRP5/6 (LDL-receptor-related proteins) ENSG00000169071 ENSG00000134982 ENSG00000168036 PMC2700428__F2 Some cellular processes implicated in the pathogenesis of PAH ENSG00000138798 ENSG00000128052 ENSG00000204217 PMC3202302__F1 Signaling by the TNFR superfamily in B-cell biology and disease ENSG00000109320 ENSG00000145321 ENSG00000127191 PMC5101203__F1 Putative pathological production of AB and NFKB signaling in neurons ENSG00000122877 PMC3202302__F2 Signaling by the TNFR superfamily in B-cell biology and disease ENSG00000104856 ENSG00000186716 PMC3202302__F5 Signaling by the TNFR superfamily in B-cell biology and disease ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC6216024__F1 Hedgehog signaling pathway ENSG00000166813 ENSG00000128602 PMC3202302__F4 Signaling by the TNFR superfamily in B-cell biology and disease ENSG00000177455 ENSG00000095585 ENSG00000104856 ENSG00000124102 ENSG00000002330 ENSG00000150907 ENSG00000197943 ENSG00000131323 ENSG00000127191 ENSG00000010671 PMC9362470__F1 Sulfide metabolite formation and fate ENSG00000205795 ENSG00000116761 PMC9044756__F10 Increased expression of NOP14 is associated with improved prognosis due to immune regulation in colorectal cancer ENSG00000134982 ENSG00000168036 PMC5523822__F2 Altered B cell signalling in autoimmunity ENSG00000186716 ENSG00000015285 PMC8617922__F1 Pentoxifylline as a Potential Adjuvant Therapy for COVID-19: Impeding the Burden of the Cytokine Storm ENSG00000116030 PMC9433872__F6 Research progress on RNA−binding proteins in breast cancer ENSG00000153944 ENSG00000136997 ENSG00000131023 PMC9120625__AF1 Antidepressant-like effect of ginsenoside Rb1 on potentiating synaptic plasticity via the miR-134–mediated BDNF signaling pathway in a mouse model of chronic stress-induced depression ENSG00000168036 ENSG00000139687 PMC3175751__F2 Schematic Overview of Nodal and Cripto-1 Signaling Pathways ENSG00000291971 ENSG00000156574 PMC3188749__F3 Simplified schematic presentation of the transcriptional hierarchy of essential factors and signaling pathways during endocrine specification of the pancreatic endoderm ENSG00000139515 ENSG00000117707 ENSG00000106331 PMC4118249__F9 Theoretical structure of this triple-hit nALI model as a translational study ENSG00000109321 ENSG00000172936 ENSG00000136869 PMC6173119__F2 Regulation of intestinal cholesterol absorption and role of the Niemann-Pick C1-like 1 protein (NPC1L1) at the enterocyte level in humans ENSG00000138075 ENSG00000042832 ENSG00000138823 ENSG00000015520 ENSG00000113161 ENSG00000120437 ENSG00000143921 PMC8703276__F1 Methylenetetrahydrofolate (MTHFR), the One-Carbon Cycle, and Cardiovascular Risks ENSG00000228716 PMC2723786__F1 BCL6 represses CHEK1 and suppresses DNA damage pathways in normal and malignant B-cells ENSG00000149311 ENSG00000175054 ENSG00000137265 ENSG00000149554 PMC4865891__F6 Loss of Interleukin-21 Receptor Activation in Hypoxic Endothelial Cells Impairs Perfusion Recovery after Hindlimb Ischemia ENSG00000168610 PMC7486457__F8 Proposed model for the relationship between NRF2-FOCAD-FAK signaling and cysteine deprivation-induced ferroptosis ENSG00000167468 ENSG00000167996 ENSG00000132383 ENSG00000085662 PMC9661362__F2 Central Adiponectin Signaling – A Metabolic Regulator in Support of Brain Plasticity ENSG00000157500 ENSG00000159346 ENSG00000285070 PMC7352710__F1 A-proliferation inducing ligand/B cell maturation antigen (APRIL/BCMA) pathway and its biological effect in the multiple myeloma bone marrow microenvironment ENSG00000023445 ENSG00000042832 ENSG00000171791 ENSG00000049768 PMC6347560__F1 Ribosomal stress (RS) pathway and its hypothetical role in neurodevelopmental syndromes ENSG00000101751 ENSG00000181163 ENSG00000166169 PMC8546207__F4 Determinants of Innate Immunity in Visceral Leishmaniasis and Their Implication in Vaccine Development ENSG00000125538 ENSG00000162692 PMC3931013__F3 Wnt signaling pathway represented by KEGG analysis ENSG00000281324 ENSG00000162337 ENSG00000102908 ENSG00000134982 ENSG00000050748 ENSG00000149782 ENSG00000168036 ENSG00000104332 ENSG00000196628 ENSG00000169750 ENSG00000147869 ENSG00000155760 ENSG00000101333 ENSG00000087095 ENSG00000156076 ENSG00000137673 ENSG00000005339 ENSG00000292149 ENSG00000067900 ENSG00000100888 ENSG00000137841 ENSG00000163904 ENSG00000101849 ENSG00000115266 ENSG00000104290 ENSG00000285485 PMC7325303__F1 Apoptosis in health and disease: the balancing act of BCL-2 family proteins ENSG00000002330 ENSG00000136997 ENSG00000120868 ENSG00000171791 ENSG00000135116 PMC3736724__F1 Tyrosine kinase (TYK) targeting growth factor and proliferation pathways ENSG00000128052 PMC6824075__F10 Working model for the SULF2‐LAPTM4B‐dependent autophagic pathway in HCC cells ENSG00000196562 ENSG00000104341 PMC8898188__F1 Cross-Communication Between Knee Osteoarthritis and Fibrosis: Molecular Pathways and Key Molecules ENSG00000087095 ENSG00000125398 ENSG00000134982 ENSG00000168036 PMC8533955__F2 Towards Understanding the Direct and Indirect Actions of Growth Hormone in Controlling Hepatocyte Carbohydrate and Lipid Metabolism PMC9185410__F3 Mechanism Involved in Acute Liver Injury Induced by Intestinal Ischemia-Reperfusion ENSG00000137033 ENSG00000189403 ENSG00000168404 PMC3263503__F8 Schematic depiction of crosstalk between Notch and HIF-1A ENSG00000134086 ENSG00000005339 ENSG00000168610 PMC7968318__F4 VIRMA and circ_KIAA1429 involved in human cancer progression ENSG00000164944 ENSG00000136997 ENSG00000107485 PMC7505271__F4 Relationships between mitochondrial and norepinephrine dysfunctions ENSG00000113600 ENSG00000123454 PMC6752849__F10 Proton pump inhibitors attenuate myofibroblast formation associated with thyroid eye disease through the aryl hydrocarbon receptor ENSG00000168036 ENSG00000106546 PMC3691204__F1 Mutational Analysis of Hedgehog Signaling Pathway Genes in Human Malignant Mesothelioma ENSG00000106571 ENSG00000117425 ENSG00000164161 ENSG00000166813 ENSG00000128602 PMC11274091__F3 Interrelationship of major pathways and coexisting inflammatory mediators between oxidative stress and inflammatory process in excisional skin wound healing ENSG00000162711 ENSG00000162924 ENSG00000005381 ENSG00000132693 ENSG00000167419 PMC8022410__F8 GSK3B rephosphorylation rescues ALPL deficiency-induced impairment of odontoblastic differentiation of DPSCs ENSG00000168036 ENSG00000152592 ENSG00000152591 PMC4509139__F3 Map of the Wnt signaling pathway, which includes at least three Wnt signaling pathways, namely the canonical pathway, the planar cell polarity pathway and the Wnt/Ca2+pathway ENSG00000087095 ENSG00000100592 ENSG00000095739 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000113558 ENSG00000111653 ENSG00000168036 PMC11203986__F10 DAXX-associated pathway ENSG00000101945 ENSG00000143379 PMC8155577__F2 Ancient Adversary – HERV-K (HML-2) in Cancer ENSG00000088888 ENSG00000168036 ENSG00000276561 ENSG00000164342 PMC7005898__F6 Proposed function of HadDMtb in the mycolic acid biosynthetic pathway of M ENSG00000166278 PMC8222669__F2 Protective Mechanism of Humanin Against Oxidative Stress in Aging-Related Cardiovascular Diseases ENSG00000181019 ENSG00000178573 ENSG00000100387 ENSG00000086991 ENSG00000187134 ENSG00000079999 PMC9508752__F3 Profiles of transcriptome and metabolic pathways after hypobaric hypoxia exposure ENSG00000038002 PMC8222669__F6 Protective Mechanism of Humanin Against Oxidative Stress in Aging-Related Cardiovascular Diseases ENSG00000198793 ENSG00000168610 ENSG00000079999 PMC6361458__F5 Molecular insights in the pathogenesis of classical Ehlers-Danlos syndrome from transcriptome-wide expression profiling of patients’ skin fibroblasts ENSG00000101901 ENSG00000152348 ENSG00000133110 ENSG00000118785 ENSG00000092853 ENSG00000115457 ENSG00000143476 ENSG00000164176 ENSG00000172404 ENSG00000198168 ENSG00000124762 ENSG00000175305 PMC7505271__F2 Relationships between mitochondrial and serotoninergic dysfunctions ENSG00000113600 PMC6028704__F1 Sub-network with a size cut-off of 28 between D-glucose and L-phenylalanine in S ENSG00000159224 ENSG00000198324 ENSG00000122966 ENSG00000173599 PMC9468880__F2 Recent advances of the mammalian target of rapamycin signaling in mesenchymal stem cells ENSG00000120149 ENSG00000198793 ENSG00000284161 ENSG00000118515 ENSG00000164327 ENSG00000239282 PMC10353343__F4 Gene expression changes for genes in the Toll-like receptor 4 (TLR4) Signaling Pathway ENSG00000170458 ENSG00000172005 ENSG00000172936 ENSG00000157625 ENSG00000130159 ENSG00000162692 ENSG00000175104 ENSG00000184216 ENSG00000010671 PMC6526306__F6 BCAA mediate resilience to stress by inducing the hippocampal BNDF/TRKB signaling through the PGC1a/FNDC5 pathway ENSG00000160097 ENSG00000158104 PMC3858599__F1 NAD+ metabolism, a therapeutic target for age-related metabolic disease ENSG00000100473 ENSG00000105835 ENSG00000123572 PMC4570748__F7 Redox control of the cellular energy metabolism ENSG00000149311 ENSG00000198793 PMC2374962__F2 Regulation of glycolysis and fatty acid synthesis ENSG00000169710 ENSG00000078237 ENSG00000284194 PMC8832002__F7 S100A4/TCF Complex Transcription Regulation Drives Epithelial-Mesenchymal Transition in Chronic Sinusitis Through Wnt/GSK-3B/Beta-Catenin Signaling ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000170558 ENSG00000196154 ENSG00000168036 ENSG00000108821 ENSG00000196628 PMC3789189__F8 CVB3-induced the PI3K-Akt-mTOR-apoptosis signaling pathway PMC4102553__F5 Serum Metabolomic Response of Myasthenia Gravis Patients to Chronic Prednisone Treatment PMC4102553__F4 Serum Metabolomic Response of Myasthenia Gravis Patients to Chronic Prednisone Treatment ENSG00000108839 ENSG00000183876 PMC6321704__F1 Simplified reference TLR signaling pathway projected onto putative homologs in Trichoplax sp ENSG00000137265 ENSG00000157625 ENSG00000076604 PMC3822957__F11 P60TRP signalling based on the results obtained from different systems including NSCs, PC12 cells and p60TRP transgenic mice ENSG00000142192 ENSG00000148400 ENSG00000170558 ENSG00000137845 PMC3975365__F3 So-called PI3-K/Akt/mTOR survival pathway ENSG00000113600 ENSG00000002330 ENSG00000198793 ENSG00000276876 PMC2812788__F1 HDL, ABCA1 and ABCG1 transporters in cholesterol efflux and immune responses ENSG00000170458 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000160179 PMC3975365__F2 Tumor’s interaction with its solid microenvironment ENSG00000002330 ENSG00000291971 ENSG00000168036 PMC3975365__F1 Apoptosis induction and signaling ENSG00000084774 PMC3752265__F5 Example of differences in use between glycolysis and the ED pathway by representative cells in our modeled population ENSG00000197713 ENSG00000166816 PMC7533558__F9 How CRLF1 promotes HLF formation ENSG00000087245 ENSG00000108924 ENSG00000125538 ENSG00000006016 PMC7792207__F4 Survivin and interaction with apoptotic pathways ENSG00000132530 ENSG00000006712 ENSG00000168040 PMC7912776__F1 Genetics of extreme human longevity to guide drug discovery for healthy ageing ENSG00000171105 ENSG00000281324 ENSG00000162337 ENSG00000169047 ENSG00000145979 PMC5466966__F1 Major Anti-tumorigenic pharmacological properties of thymoquinone ENSG00000291971 ENSG00000135446 ENSG00000171791 ENSG00000100985 ENSG00000168610 PMC5650339__F8 miR-146a promotes growth of osteosarcoma cells by targeting ZNRF3/GSK-3B/Beta-catenin signaling pathway ENSG00000183579 ENSG00000168036 ENSG00000123908 PMC7792207__F3 Pathway involving the non-canonical NF-kB activation through NF-kB-inducing kinase (NIK/MAP3K14), modulated by cIAPs ENSG00000104856 ENSG00000131323 ENSG00000127191 PMC3979117__F1 Schematic illustration summarizing apoptotic signaling through the death receptor pathway and the mitochondrial pathway ENSG00000002330 ENSG00000096717 ENSG00000026103 ENSG00000198625 PMC10971254__F8 Binding of IL-25 to its receptor induces the transcription of IL-25 responsive genes via the TRAF6/NFKB-dependent signaling cascade and TRAF4/MAPK/AP-1-dependent signaling pathway ENSG00000166090 ENSG00000056736 ENSG00000175104 ENSG00000076604 PMC8540239__F3 An Insight into Anti-Inflammatory Activities and Inflammation Related Diseases of Anthocyanins: A Review of Both In Vivo and In Vitro Investigations ENSG00000170458 ENSG00000150455 ENSG00000175104 PMC4574248__F2 Signal transduction pathways and the oxidative stress response ENSG00000132964 ENSG00000108510 PMC8065760__F3 Involvement of the significantly dysregulated microRNAs in renal cancer signaling pathways ENSG00000134086 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC1168613__F1 Comparison of the D ENSG00000172936 ENSG00000162924 ENSG00000168040 PMC11711753__F6 Extending a canonical pathway with PTMNavigator ENSG00000105722 ENSG00000172680 ENSG00000157764 ENSG00000102606 ENSG00000104969 ENSG00000115904 ENSG00000141639 ENSG00000126883 ENSG00000067900 ENSG00000281877 ENSG00000079432 ENSG00000069956 ENSG00000169032 ENSG00000100485 ENSG00000065978 PMC11711753__F4 Analysis of a phosphoproteomic perturbation dataset in PTMNavigator ENSG00000157764 ENSG00000198793 ENSG00000169047 ENSG00000145979 ENSG00000136997 ENSG00000164327 ENSG00000141564 ENSG00000146648 PMC9502658__F2 Ivermectin: A Controversial Focal Point during the COVID-19 Pandemic ENSG00000130234 ENSG00000184012 ENSG00000276561 PMC3735083__F1 HIF-1A regulation in cancer ENSG00000127445 ENSG00000198793 ENSG00000076321 ENSG00000140464 PMC7910460__F4 Crosstalk between HIFs and mitochondrial dysfunctions in cancer development ENSG00000134086 ENSG00000042832 ENSG00000116688 ENSG00000158828 PMC9108985__F1 Cellular proteostasis in antitumor immunity ENSG00000284774 PMC4292903__F2 Biomarkers Linking PCB Exposure and Obesity ENSG00000170122 ENSG00000150907 ENSG00000156574 PMC4607614__F6 Schematic representation of SA’s mechanisms of suppression of HMGB1’s proinflammatory activities ENSG00000189403 ENSG00000136869 ENSG00000121966 PMC3739146__F7 NAC protects against Cd-induced germ cell apoptosis by inhibiting UPR signalling in the testes ENSG00000144895 ENSG00000100219 PMC6885792__F2 The role of MYOF in membrane trafficking ENSG00000138119 ENSG00000112715 ENSG00000146648 PMC8170419__F3 Intersectional analysis of chronic mild stress-induced lncRNA-mRNA interaction networks in rat hippocampus reveals potential anti-depression/anxiety drug targets ENSG00000169291 ENSG00000090402 ENSG00000124733 ENSG00000254550 PMC6885792__F3 Role of MYOF in EGFR-related pathway ENSG00000138798 ENSG00000138119 ENSG00000146648 PMC8255612__F1 BMP Signaling in Endothelial Heterogeneity ENSG00000137834 ENSG00000204217 PMC4984662__F8 Bunyavirus-induced Wnt/Beta-catenin signaling ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4729952__F3 Peroxisomes, fatty acid beta-oxidation and the human deficiencies of peroxisomal beta-oxidation ENSG00000142538 ENSG00000105516 ENSG00000161533 PMC3193402__F2 Crosstalk between RANKL- and TNF-induced NFKB signaling in OCs ENSG00000104856 ENSG00000131323 PMC5798385__F7 Proposed model for regulation of S6 phosphorylation (P) by the cAMP/PKA pathway ENSG00000155792 ENSG00000167965 PMC8463593__F10 BAFF is involved in B cell differentiation and activation through the NFKB signaling pathway in RA ENSG00000177455 ENSG00000139193 ENSG00000132693 PMC3193402__F1 Classical and alternative NFKB pathways in skeletal cells ENSG00000104856 PMC5411693__F6 Hypothesized altered feedback control of the POMC gene promoter in cells having USP8 or RASD1 mutations (mut) versus wild type (wt) ENSG00000108551 ENSG00000115138 ENSG00000146648 PMC8712487__F2 Myosin 1g and 1f: A Prospective Analysis in NK Cell Functions ENSG00000187608 ENSG00000142347 ENSG00000136286 PMC4459616__F3 Effect of sclerostin inhibition on Wnt signaling.Notes: Sclerostin is secreted by the osteocyte ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000167074 PMC8667691__F1 Action And Clinical Implications of MicroRNAs in the Drug Resistance of Gastric Cancer ENSG00000138231 ENSG00000128191 ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC4459616__F1 Wnt signaling pathways and the biology of sclerostin.Notes: (A) Canonical Wnt signaling: in the absence of sclerostin, Wnt binds to LRP 5/6 and its co-receptor, frizzled ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC9061994__F4 ROS-Influenced Regulatory Cross-Talk With Wnt Signaling Pathway During Perinatal Development ENSG00000134982 ENSG00000168036 PMC8483823__F4 Profile analysis of circular RNAs in cervical cancer ENSG00000170458 ENSG00000121053 ENSG00000026103 PMC3000367__F5 Scalable Approach for Discovering Conserved Active Subnetworks across Species ENSG00000145632 ENSG00000137273 ENSG00000198053 ENSG00000134057 ENSG00000081237 ENSG00000166402 ENSG00000152977 ENSG00000156925 ENSG00000101057 ENSG00000125810 ENSG00000158869 PMC9114355__F1 Adipose Tissue Derived Exosomes in Metabolic Disease ENSG00000110651 ENSG00000010278 ENSG00000135404 PMC5620210__F2 ABI3, a component of the WAVE2 complex, is potentially regulated by PI3K/AKT pathway ENSG00000070831 ENSG00000291971 ENSG00000134982 ENSG00000010810 ENSG00000198793 ENSG00000168036 PMC7432514__F3 Human diseases linked to eIF2 Ser-51 phosphorylation stress responses and the mTORC1 signaling pathway ENSG00000128272 ENSG00000198793 PMC7875453__F2 BCR signaling pathways ENSG00000095585 ENSG00000109320 ENSG00000291971 ENSG00000186716 ENSG00000173039 ENSG00000197943 ENSG00000175104 ENSG00000127191 ENSG00000010671 PMC12154905__F3 Scheme of the identified TNF signaling pathway, with genes identified by changes in mRNA levels in NS1-treated human lung microvascular endothelial cells (HLMVECs) compared to untreated control cells ENSG00000167207 ENSG00000007908 ENSG00000168040 ENSG00000127191 ENSG00000125347 ENSG00000164305 ENSG00000157227 ENSG00000149968 ENSG00000118503 ENSG00000078747 ENSG00000056558 ENSG00000075891 ENSG00000131323 ENSG00000128342 ENSG00000083799 ENSG00000168404 ENSG00000026103 ENSG00000084774 PMC8266488__F3 Sex Hormones and Gender in the Gut Microbiota ENSG00000291971 ENSG00000185591 PMC5777791__F9 Curcumol potentiates celecoxib-induced growth inhibition and apoptosis in human non-small cell lung cancer ENSG00000145604 PMC6772763__F8 Multiple signaling pathways regulate the cell death pathway in sympathetic neurons ENSG00000177606 PMC7407234__F6 Proposed model for MX1’s role in ERS-mediated cell fate ENSG00000128272 ENSG00000157601 ENSG00000100219 PMC11702355__F2 Classical and non-classical Wnt signaling pathways ENSG00000137673 ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000125084 PMC7975969__F3 Suppression effect of starvation in anorexia nervosa on mTOR system and end organ results ENSG00000169047 ENSG00000198793 ENSG00000155792 PMC7975969__F2 Nutrient effects in activation of mTOR system and the end-organ results ENSG00000169047 ENSG00000198793 ENSG00000155792 PMC8871376__F1 Adenylosuccinate lyase (ADSL) in de novo purine synthesis (DNPS) and the purine nucleotide cycle ENSG00000128050 ENSG00000156110 ENSG00000196839 ENSG00000291814 ENSG00000137198 PMC6459027__F1 Thiamine metabolism ENSG00000196511 ENSG00000259431 PMC10990754__F1 Various intracellular signaling molecules and pathways involved in HSCR ENSG00000169554 ENSG00000187871 ENSG00000100146 ENSG00000169618 ENSG00000185652 ENSG00000075223 ENSG00000153993 ENSG00000163421 ENSG00000198954 ENSG00000164690 ENSG00000163501 ENSG00000171119 ENSG00000109132 ENSG00000117407 ENSG00000125650 PMC4962366__F8 Gene network ENSG00000113889 ENSG00000101440 ENSG00000185231 ENSG00000124089 PMC8810962__F4 Estradiol supplementation on the brain transcriptome of old rhesus macaques maintained on an obesogenic diet ENSG00000151834 ENSG00000145864 ENSG00000011677 ENSG00000113327 ENSG00000101438 ENSG00000132164 ENSG00000268089 ENSG00000135018 PMC10990754__F3 NcRNAs related to cell apoptosis, proliferation, migration, and differentiation in HSCR ENSG00000112242 ENSG00000196935 ENSG00000077279 ENSG00000182621 ENSG00000125861 PMC4281037__F4A IL-23-IL-17 immune axis: Discovery, Mechanistic Understanding, and Clinical Testing ENSG00000183735 ENSG00000082512 ENSG00000157625 ENSG00000131323 ENSG00000155313 ENSG00000175104 ENSG00000127191 ENSG00000163702 ENSG00000076604 PMC5545069__F2 Iron Overload and Altered Iron Metabolism in Ovarian Cancer ENSG00000115107 PMC9283756__F2 Circadian Rhythms Coordinated With Gut Microbiota Partially Account for Individual Differences in Hepatitis B-Related Cirrhosis ENSG00000167910 ENSG00000132693 ENSG00000004848 ENSG00000163884 PMC7648632__F1 PD-L1 degradation pathway and immunotherapy for cancer ENSG00000149311 ENSG00000091317 ENSG00000183723 ENSG00000135446 ENSG00000121067 ENSG00000168036 ENSG00000105810 ENSG00000146648 ENSG00000196628 PMC8834120__F3 Landscape of PDK1 in Breast Cancer ENSG00000002330 PMC11947053__F2 Research progress and prospect of MAPK signaling pathway in knee osteoarthritis ENSG00000157557 ENSG00000099985 ENSG00000177606 ENSG00000136997 ENSG00000175104 ENSG00000127191 PMC8834120__F4 Landscape of PDK1 in Breast Cancer ENSG00000139211 PMC9384889__F8 Molecular Mechanism of Xingnao Kaiqiao Pill for Perioperative Neurocognitive Disorder and Its Correlation With Immune and Inflammatory Signaling Pathways Based on Network Pharmacology and Molecular Docking ENSG00000148346 ENSG00000162924 PMC7971348__F2 Ubiquitin-proteasome pathway influences proteostasis, the cell cycle, and filamentation ENSG00000134982 ENSG00000113558 ENSG00000117399 PMC9384889__F7 Molecular Mechanism of Xingnao Kaiqiao Pill for Perioperative Neurocognitive Disorder and Its Correlation With Immune and Inflammatory Signaling Pathways Based on Network Pharmacology and Molecular Docking ENSG00000167207 ENSG00000078747 ENSG00000168040 ENSG00000168404 ENSG00000074410 ENSG00000127191 PMC7648632__F2 PD-L1 degradation pathway and immunotherapy for cancer ENSG00000091317 ENSG00000138798 ENSG00000173599 ENSG00000137845 ENSG00000146648 ENSG00000179913 PMC7071987__F1 Fundamental knowledge on IL-17 biology ENSG00000108691 ENSG00000163739 ENSG00000056736 ENSG00000175104 ENSG00000127191 ENSG00000163702 PMC1805736__F6 Pathways for synthesis of adrenal steroids ENSG00000179142 PMC3640439__F1 Induction and evasion of type I interferon responses by influenza viruses ENSG00000088888 ENSG00000172936 ENSG00000164342 PMC4706689__F2 IL-10 Anti-inflammatory Signaling Pathway is enriched for putative differentially expressed genes (Progressors vs NonProgressors Enrichment False Discovery Rate adjusted P-value = 0.0287) Figure is a stylized representation of the Biocarta pathway ENSG00000138378 ENSG00000173757 ENSG00000110324 PMC9097893__F2 NLRX1 Deficiency Alters the Gut Microbiome and Is Further Exacerbated by Adherence to a Gluten-Free Diet ENSG00000104856 ENSG00000107562 ENSG00000137033 ENSG00000160703 ENSG00000091592 ENSG00000274571 ENSG00000131323 ENSG00000127191 PMC8921673__F1 Roles of Glucagon-Like Peptide-1 and Its Analogues in Dementia Targeting Impaired Insulin Secretion and Neurodegeneration ENSG00000169047 ENSG00000281879 PMC10454639__F11 Regulatory pathway map of roots suffering Mn poisoning in soybean PMC4706689__F1 IL-10 and integrin signaling pathways are associated with head and neck cancer progression ENSG00000105664 ENSG00000140678 ENSG00000169896 ENSG00000259207 ENSG00000166086 ENSG00000292234 ENSG00000005961 ENSG00000118785 ENSG00000188157 ENSG00000135424 ENSG00000171560 ENSG00000137801 PMC5638382__F1 Different endothelial responses to different patterns of flow ENSG00000127528 ENSG00000136826 PMC6893739__F2 Merlin signaling ENSG00000149269 ENSG00000198793 ENSG00000026508 ENSG00000150457 ENSG00000131023 PMC7559019__F4 Various factors influence the occurrence of liver cancer ENSG00000186575 ENSG00000173599 PMC8921673__F2 Roles of Glucagon-Like Peptide-1 and Its Analogues in Dementia Targeting Impaired Insulin Secretion and Neurodegeneration ENSG00000142192 ENSG00000169291 ENSG00000136111 PMC7848033__F1 Role of Osteocytes in Modifying Bone Matrix Properties ENSG00000152266 ENSG00000167941 ENSG00000152592 ENSG00000108821 ENSG00000143387 PMC7925099__F15 The action of PAV-206, a possible first-in-class selective inhibitor of HIV-1 assembly ENSG00000114127 PMC3265866__F7 PGC-1Alpha- and AMPK-mediated regulation of IL1Rn expression in hepatocytes ENSG00000125538 ENSG00000132693 ENSG00000136689 PMC5889282__F7 BGN- and DCN-mediated inhibition of the TGFB pathway and restriction of HER-2/neu signaling ENSG00000146648 PMC9532189__F1 Serum Homocysteine and Vascular Calcification: Advances in Mechanisms, Related Diseases, and Nutrition ENSG00000111341 PMC8699554__F4 COVID-19 and Rheumatoid Arthritis Crosstalk: Emerging Association, Therapeutic Options and Challenges ENSG00000117091 ENSG00000118785 ENSG00000163221 ENSG00000125538 ENSG00000085265 ENSG00000165457 PMC7072680__F1 gp130 cytokines and receptors activate downstream signaling pathways ENSG00000145623 ENSG00000099985 ENSG00000242689 ENSG00000122756 ENSG00000105246 ENSG00000128342 PMC8699554__F1 COVID-19 and Rheumatoid Arthritis Crosstalk: Emerging Association, Therapeutic Options and Challenges ENSG00000111537 ENSG00000134982 ENSG00000132693 PMC7299830__F3 Eribulin combined with irinotecan inhibits DNA replication and induces TP53 pathway genes ENSG00000104499 ENSG00000152409 ENSG00000118007 ENSG00000033800 ENSG00000168036 ENSG00000012048 ENSG00000132646 ENSG00000186716 ENSG00000048052 ENSG00000112378 ENSG00000284194 ENSG00000140464 ENSG00000026103 ENSG00000198625 PMC420513__F4 Immune synapse_related signaling pathway and autoimmune diseases ENSG00000159216 ENSG00000213658 ENSG00000010810 ENSG00000109065 ENSG00000124181 ENSG00000067955 ENSG00000197208 ENSG00000188389 PMC7757038__F1 Exosome biogenesis and composition ENSG00000041353 ENSG00000085117 ENSG00000108557 ENSG00000074319 ENSG00000110651 ENSG00000010278 ENSG00000135404 ENSG00000165527 ENSG00000111737 PMC5694456__F9 Schematic illustration revealing the anti-inflammatory effects of gApN on microglia ENSG00000125538 ENSG00000159346 PMC3881972__F1 Inhibition of pattern recognition receptor-mediated inflammation by bioactive phytochemicals: a review of recent research ENSG00000135218 ENSG00000167207 ENSG00000187796 ENSG00000170458 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000106100 ENSG00000164342 PMC4987160__F4 Genomic Landscape of Male Breast Cancers ENSG00000132781 ENSG00000187741 PMC5932347__F1 RIG-I-like receptors and toll-like receptor (TLR) 3 signaling pathway ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000175104 ENSG00000276561 PMC3048839__F10 Schematic representation of IH-induced increase in adrenal medullary NPY by activation of reactive oxygen species (ROS) signaling pathway PMC7828553__F2 FGFR signaling pathway PMC4384349__F5 Schematic presentation of VEGFR-1 activation in CC tissue and its association with metastasis ENSG00000112715 PMC12111897__F6 Signal transduction pathways for the Al+ADAl3–4 vs ENSG00000110934 ENSG00000221818 ENSG00000011143 PMC3592471__F8 Functionally related pathways of aberrantly methylated and differentially expressed genes in immortalized MEFs ENSG00000185386 ENSG00000185591 ENSG00000139890 ENSG00000141026 ENSG00000165462 PMC7819155__F2 Roles of the lncRNA H19 in osteogenic differentiation ENSG00000168036 PMC12120737__F5 PCSK9 activated the EGFR/HER3 signaling pathway in TNBC cells ENSG00000112576 ENSG00000130164 ENSG00000291971 ENSG00000146648 ENSG00000169174 PMC9395634__F4 MiRNA and associated inflammatory changes from baseline to hypoglycemia in type 2 diabetes ENSG00000150938 ENSG00000143248 ENSG00000132541 ENSG00000125148 ENSG00000095739 ENSG00000105193 ENSG00000166863 ENSG00000176907 PMC5386953__F2 Signaling Pathways Controlling Microglia Chemotaxis ENSG00000135218 ENSG00000291971 PMC9395634__F3 MiRNA and associated inflammatory changes from baseline to hypoglycemia in type 2 diabetes ENSG00000204262 ENSG00000138316 ENSG00000166106 ENSG00000170275 ENSG00000151914 ENSG00000104907 ENSG00000087116 PMC3848550__F2 Schematic representation of the sialic acid metabolism pathway in eukaryotic cells ENSG00000162139 ENSG00000069482 ENSG00000115488 ENSG00000073849 PMC8509620__F8 Lysophosphatidic Acid Mediates Imiquimod-Induced Psoriasis-like Symptoms by Promoting Keratinocyte Proliferation through LPAR1/ROCK2/PI3K/AKT Signaling Pathway ENSG00000135446 ENSG00000123374 ENSG00000198670 ENSG00000145386 PMC7797432__F2 SFRP-2 in the Wnt/Beta-catenin signalling pathway in cancer ENSG00000157764 ENSG00000134982 ENSG00000168036 PMC5993148__F3 SLC7A11 regulates nutrient dependency of cancer cells ENSG00000168003 ENSG00000151012 ENSG00000115419 PMC3013243__F9 Myeloid-specific GPCR kinase-2 negatively regulates NFKB1p105-ERK pathway and limits endotoxemic shock in mice ENSG00000125538 ENSG00000136869 PMC11240502__F2 Tryptophan metabolites interact with AhR and potentially interfere with serotonin and melatonin synthesis ENSG00000140505 ENSG00000140465 ENSG00000106546 PMC11240502__F1 Effects of UVA and UVB radiation on skin tryptophan lead to pro-inflammatory pathways ENSG00000146648 ENSG00000106546 PMC3291637__F2 Proposed differences in the localization of Fe-S cluster biogenesis proteins in S ENSG00000103274 ENSG00000144021 ENSG00000188566 ENSG00000136003 ENSG00000169599 PMC8347979__F4 ADAM 17 and Epithelial-to-Mesenchymal Transition: The Evolving Story and Its Link to Fibrosis and Cancer ENSG00000087245 ENSG00000291971 ENSG00000100985 PMC3291637__F1 General scheme for biogenesis of Fe-S clusters in mammalian cells ENSG00000182511 ENSG00000136003 ENSG00000169599 PMC8909058__F4 Relevance of Aquaporins for Gamete Function and Cryopreservation ENSG00000178301 ENSG00000103569 ENSG00000173599 ENSG00000103375 ENSG00000165269 PMC10245950__F12 Glycolysis in cardiomyocytes is upregulated in the oxaliplatin treated mice ENSG00000130957 ENSG00000074800 ENSG00000160883 ENSG00000108515 ENSG00000164708 ENSG00000136872 ENSG00000159399 PMC10245950__F13 Effect of oxaliplatin on NAD+ and NADP+ synthesis and salvage pathways ENSG00000154269 ENSG00000105835 ENSG00000109743 ENSG00000112874 ENSG00000112992 ENSG00000142082 ENSG00000283100 ENSG00000136960 ENSG00000291814 ENSG00000001561 ENSG00000197594 ENSG00000164303 ENSG00000173614 ENSG00000122696 ENSG00000008130 ENSG00000096717 ENSG00000089163 PMC10474743__F4 Advances in immunotherapy for triple-negative breast cancer ENSG00000164430 ENSG00000163599 PMC5992481__F1 miR-24 and miR-122 Negatively Regulate the Transforming Growth FactorB/Smad Signaling Pathway in Skeletal Muscle Fibrosis PMC3856112__F7 Combination of pathway topology and ab initio reconstructed network ENSG00000275700 ENSG00000175183 ENSG00000158104 ENSG00000173641 ENSG00000157005 ENSG00000146733 ENSG00000171303 ENSG00000135899 ENSG00000138674 ENSG00000115457 ENSG00000067248 ENSG00000110906 ENSG00000092841 ENSG00000110344 ENSG00000163754 PMC5992481__F5 miR-24 and miR-122 Negatively Regulate the Transforming Growth FactorB/Smad Signaling Pathway in Skeletal Muscle Fibrosis PMC4114960__F4 Viral-Induced Rewiring of Host Metabolism Leads to an Increase in Fatty Acid Biosynthesis ENSG00000092621 ENSG00000146733 PMC6165581__F2 Illustration of miRNA biogenesis pathway and mode of gene regulation ENSG00000128191 ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC5490158__F4 Upstream regulators identified by Ingenuity Pathway Analysis, predicted to participate in the regulation of gene expression upon A2B-adrenoceptor activation in A7r5A2B vascular smooth muscle cells ENSG00000108691 ENSG00000120937 ENSG00000106546 PMC9158472__F6 NFE2L3 as a Novel Biomarker Associated With IL-2/STAT5/NLRP3 Signaling Pathway in Malignant Pleural Mesothelioma and Other Cancers ENSG00000162711 ENSG00000050344 ENSG00000113520 ENSG00000113525 PMC7604315__F2 Neddylation and HCC ENSG00000134086 ENSG00000285246 ENSG00000281857 PMC5873813__F2 Broad overview of the genetic architecture of inflammatory bowel disease giving examples of confirmed and candidate genes implicated in each pathway ENSG00000167207 ENSG00000142330 ENSG00000197272 ENSG00000237693 ENSG00000243509 ENSG00000168610 ENSG00000162594 ENSG00000164691 ENSG00000105397 ENSG00000100330 ENSG00000160223 ENSG00000136869 ENSG00000172057 ENSG00000100219 ENSG00000112486 PMC3457296__F8 LMP2A induces signaling pathways that promote membrane localization of AV-integrin and epithelial migration ENSG00000291971 PMC5977110__F5 Pathways that influence YAP and TAZ in lung cancer ENSG00000068028 ENSG00000138798 ENSG00000168036 ENSG00000143322 ENSG00000198670 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC4817727__F3 Role of axin in Wnt signaling in bone ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4817727__F4 Role of RGS proteins in selected GPCR signaling in bone ENSG00000143248 ENSG00000150681 ENSG00000148908 ENSG00000116741 ENSG00000036828 ENSG00000131196 ENSG00000159788 PMC5977110__F1 Hippo pathway core components and their upstream regulators ENSG00000163914 ENSG00000168036 ENSG00000198670 ENSG00000150457 ENSG00000131023 PMC5977110__F2 Main proteins and pathways that influence YAP and TAZ in lung development and tumorigenesis ENSG00000068028 ENSG00000126016 ENSG00000130545 ENSG00000138798 ENSG00000143322 ENSG00000198670 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC5585663__F1 The Nrf2/Keap1/ARE pathway in type II diabetes mellitus ENSG00000181019 ENSG00000079999 PMC3873541__F7 Enriched canonical pathways of miRNA target genes ENSG00000132906 ENSG00000002330 ENSG00000169047 ENSG00000169032 ENSG00000168610 ENSG00000081189 ENSG00000089159 ENSG00000007171 ENSG00000160691 ENSG00000179295 ENSG00000122025 ENSG00000069869 ENSG00000159216 ENSG00000177606 ENSG00000106070 ENSG00000118520 ENSG00000140443 PMC9181071__F1 Natural Extracts of Andrographis paniculata That Target Lipid-Dependent Cancer Pathways: A View from the Signaling Pathway ENSG00000042832 ENSG00000138798 ENSG00000198793 ENSG00000196591 ENSG00000172936 PMC6973314__F11 Role of BST2, E-cadherin, and signaling pathways in IFN-Gamma-mediated decrease in invasion of HTR-8/SVneo cells ENSG00000115415 PMC10245950__F10 TCA cycle is affected by oxaliplatin ENSG00000143158 ENSG00000073578 ENSG00000100412 ENSG00000163541 ENSG00000105953 ENSG00000172340 ENSG00000146701 ENSG00000101365 ENSG00000060762 ENSG00000062485 PMC10706216__F16 Activation of UPR signaling pathways during ER-stress, caused by TAA injections, in liver cells ENSG00000128272 ENSG00000127191 PMC6131589__F1 Sights and mechanisms of mHTT toxicity in yeast models of HD ENSG00000197386 PMC2894449__F1 Stages of apoptotic cell engulfment and associated cell signaling events that regulate each stage ENSG00000135218 ENSG00000170458 ENSG00000005893 ENSG00000203710 PMC8926903__F1 Genomic and transcriptomic landscapes of clock genes reveal the significance of circadian rhythm in the progression and immune microenvironment of metastatic colorectal cancer ENSG00000129221 ENSG00000179094 PMC4813390__F3 Influence of TGFB‐SMAD and TGFB‐TAK1 signalling on adrenoceptor‐mediated pathways in LV heart failure progression PMC3474280__F1 Central position of the locus coeruleus in relation to the acoustic startle reflex and pupillary light reflex pathways ENSG00000213658 ENSG00000062485 PMC5693031__F7 Tight junction pathway overrepresented among Qki5 HITS-CLIP target genes based on DAVID-KEGG pathway analysis ENSG00000147044 ENSG00000169213 ENSG00000070831 ENSG00000135446 ENSG00000163914 ENSG00000168036 ENSG00000132849 ENSG00000072415 PMC4693890__F3 Cytokine signalling networks in women with chlamdyial infections (a) or gonorrhoea (b) were evaluated using Ingenuity Pathway Analysis ENSG00000277943 PMC6678762__F6 Schematic diagram illustrating the proposed SIRT1 signaling pathway involved in PGC1A/mitochondrial biogenesis that exerted an endogenous protective mechanism in the hippocampal neuronal tissue following experimental status epilepticus ENSG00000096717 ENSG00000106459 PMC11897032__F1 Pathways of serine synthesis and metabolism ENSG00000284320 ENSG00000092621 PMC5343774__F2 Summary of cross-talk between cancer cells and the tumour microenvironment mediated through the 5-lipoxygenase pathway ENSG00000283887 PMC8207819__F1 Regulated cell death pathways at a glance ENSG00000278718 ENSG00000162711 ENSG00000124256 ENSG00000151012 ENSG00000137275 ENSG00000102871 ENSG00000105401 ENSG00000113161 ENSG00000074319 ENSG00000159348 ENSG00000168040 ENSG00000154124 ENSG00000168003 ENSG00000183735 ENSG00000167468 ENSG00000120868 ENSG00000083799 ENSG00000168404 ENSG00000064012 ENSG00000285379 ENSG00000127948 ENSG00000026103 PMC5343774__F3 Cross-Talk between Cancer Cells and the Tumour Microenvironment: The Role of the 5-Lipoxygenase Pathway ENSG00000125538 ENSG00000049768 PMC4917709__F2 Negative modulation of EMT by sirtuins ENSG00000137673 ENSG00000168036 ENSG00000089163 ENSG00000283100 PMC6884928__F2 Phosphatidylinositol 3-kinase (PI3K)/pAkt-kinase pathway as a central CCL5/CCR5 signalling cascade in cancer cells ENSG00000291971 PMC2781509__F1 Folate-mediated one-carbon metabolism ENSG00000284320 PMC6651563__F1 G protein-coupled receptor (GPCR) signaling ENSG00000163914 PMC8238141__F7 Proteomic analysis of mitochondrial biogenesis in cardiomyocytes differentiated from human induced pluripotent stem cells ENSG00000073614 ENSG00000164327 ENSG00000196365 ENSG00000139687 PMC5581716__F2 The ferroptosis pathway and the inducers and inhibitors of ferroptosis ENSG00000168003 ENSG00000151012 ENSG00000144410 ENSG00000167468 PMC7143295__F2 Canonical Wnt Pathway and Inhibitors of the Wnt/beta-Catenin Signaling Pathway schematic representation of the Canonical Wnt Pathway and pharmacologic inhibitors of the Wnt/beta-catenin signaling pathway ENSG00000173599 ENSG00000229894 ENSG00000168036 ENSG00000154310 PMC9347991__F1 Comprehensive review on modulation of SIRT1 signaling pathways in the immune system of COVID‐19 patients by phytotherapeutic melatonin and epigallocatechin‐3‐gallate ENSG00000130234 PMC9347991__F3 Comprehensive review on modulation of SIRT1 signaling pathways in the immune system of COVID‐19 patients by phytotherapeutic melatonin and epigallocatechin‐3‐gallate ENSG00000162711 ENSG00000125538 ENSG00000189403 ENSG00000136869 ENSG00000096717 PMC9376458__F5 Transcriptome Analysis of Dendrobine Biosynthesis in Trichoderma longibrachiatum MD33 ENSG00000160752 ENSG00000110921 ENSG00000152904 ENSG00000113161 ENSG00000117682 ENSG00000167508 PMC9347991__F2 Comprehensive review on modulation of SIRT1 signaling pathways in the immune system of COVID‐19 patients by phytotherapeutic melatonin and epigallocatechin‐3‐gallate ENSG00000162711 ENSG00000130234 ENSG00000136869 ENSG00000096717 PMC12139089__F5 Hippo signalling contributes to renal fibrosis and damage in diabetic conditions ENSG00000170365 ENSG00000198125 ENSG00000150457 ENSG00000131023 PMC2974775__F4 Ca2+ waves activate transcription factor NFAT that in turn controls cell cycle ENSG00000167323 ENSG00000293604 ENSG00000136997 PMC3676649__F2 Musashi signaling pathways associated with mammary progenitor cell expansion ENSG00000281324 ENSG00000162337 ENSG00000148400 ENSG00000050165 ENSG00000136997 ENSG00000168036 ENSG00000133961 ENSG00000184916 ENSG00000135097 PMC5041099__F3 Integrative transcriptomic meta-analysis of Parkinson’s disease and depression identifies NAMPT as a potential blood biomarker for de novo Parkinson’s disease ENSG00000160888 ENSG00000107018 ENSG00000125740 ENSG00000128016 ENSG00000105835 ENSG00000122877 ENSG00000168036 ENSG00000136630 ENSG00000170802 ENSG00000196586 ENSG00000035720 ENSG00000150782 ENSG00000106683 ENSG00000115828 ENSG00000275404 ENSG00000140379 ENSG00000084112 ENSG00000107551 ENSG00000122862 ENSG00000064012 ENSG00000169375 ENSG00000115594 ENSG00000026103 ENSG00000197635 ENSG00000172243 ENSG00000109320 ENSG00000196839 ENSG00000115590 ENSG00000163221 ENSG00000103569 ENSG00000168040 ENSG00000170425 ENSG00000197208 ENSG00000215788 ENSG00000115607 ENSG00000102858 ENSG00000115263 ENSG00000291631 ENSG00000142089 ENSG00000229474 ENSG00000278565 ENSG00000069966 PMC6690608__F1 Metabolic reprogramming in CRC ENSG00000092621 ENSG00000169710 ENSG00000115419 PMC8235403__F14 Orthosiphon stamineus Proteins Alleviate Hydrogen Peroxide Stress in SH-SY5Y Cells ENSG00000004478 ENSG00000148344 PMC5328835__F1 Role and mechanism of action of Sclerostin in bone ENSG00000152266 ENSG00000281324 ENSG00000162337 ENSG00000134569 ENSG00000167941 ENSG00000168036 PMC12139089__F3 Activation of transforming growth factor 1 (TGFB1) signalling in the development of DKD ENSG00000198793 ENSG00000168610 PMC6499508__F6 Graphical summary ENSG00000135218 ENSG00000042832 ENSG00000125735 ENSG00000113161 ENSG00000169710 ENSG00000175567 ENSG00000121807 ENSG00000150782 ENSG00000111537 ENSG00000130164 ENSG00000173599 ENSG00000107485 ENSG00000136869 ENSG00000160179 ENSG00000169174 ENSG00000198911 PMC3945336__F1 Mannose and glucose metabolic pathway PMC7202519__F7 Our hypothesis that exercise training suppressed inflammatory and apoptotic pathways and enhanced IGF1R/PI3K/Akt survival and anti-aging AMPK/SIRT1/PGC-1A associated pathways in the hippocampus of D-galactose induced aging rats ENSG00000168040 ENSG00000096717 ENSG00000140443 ENSG00000026103 PMC5595348__F11 HRS plays an important role for TLR7 signaling to orchestrate inflammation and innate immunity upon EV71 infection ENSG00000102189 ENSG00000125538 ENSG00000172936 ENSG00000131323 ENSG00000175104 PMC8627624__F1 Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation ENSG00000124102 PMC3841320__F4 Identification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells ENSG00000053747 ENSG00000157557 ENSG00000111537 ENSG00000106004 ENSG00000138166 ENSG00000060558 ENSG00000104332 ENSG00000115009 ENSG00000137801 PMC11058197__F6 Proposed model of the Notch-ROCK pathway and its biological significance ENSG00000148400 ENSG00000136869 ENSG00000184916 ENSG00000114315 ENSG00000007171 PMC3927127__F2 Cytokine-induced differentiation of human B cells in vitro: requirement for IL-21 signaling in vivo ENSG00000186716 ENSG00000103522 ENSG00000105639 ENSG00000168610 PMC6562797__F6 Flaccidoxide-13-acetate-induced apoptotic pathway in bladder cancer cells ENSG00000128272 ENSG00000002330 ENSG00000144895 ENSG00000124610 PMC4131533__F8 Interaction network of differentially expressed miRNAs and their targets: network construction can be divided into two components: miRNA-target and target-target interaction, and candidate miRNA targets were predicted by mRDB ENSG00000121989 ENSG00000111537 ENSG00000183691 ENSG00000139269 ENSG00000120693 ENSG00000163083 ENSG00000134363 ENSG00000108443 ENSG00000164093 ENSG00000080839 ENSG00000172201 PMC3714205__F2 Signaling via by cytokines and growth factors and its negative regulation by SOCS proteins ENSG00000274211 ENSG00000120833 ENSG00000171150 ENSG00000180008 PMC6946658__F1 Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy ENSG00000168003 ENSG00000088826 ENSG00000148832 ENSG00000123505 ENSG00000102172 PMC8870127__F1 Bright and the Dark Side of TGFB Signaling in Hepatocellular Carcinoma: Mechanisms, Dysregulation, and Therapeutic Implications ENSG00000137834 PMC1949901__F1 Current understanding of the pathways of fatty acid synthesis which are known to occur within the Brassicaceae ENSG00000173599 ENSG00000026103 PMC7817624__F1 Metabolic pathways in breast cancer cells ENSG00000131473 ENSG00000198793 ENSG00000136997 ENSG00000169710 ENSG00000115419 PMC7566085__F4 Identifying Drug Sensitivity Subnetworks with NETPHIX ENSG00000149311 ENSG00000186716 ENSG00000136997 ENSG00000146648 ENSG00000139687 ENSG00000010671 ENSG00000198625 PMC5858971__F2 Targeting the IL-6/JAK/STAT3 signalling axis in cancer ENSG00000291971 ENSG00000120913 ENSG00000168610 ENSG00000196396 PMC7248678__F2 Routes of pDC sensing ENSG00000239732 ENSG00000164430 ENSG00000174953 ENSG00000172936 ENSG00000276561 PMC5858971__F1 IL-6 signalling pathways ENSG00000137845 ENSG00000168610 PMC9389045__F6 Identification of Potential Ferroptosis Key Genes in the Pathogenesis of Lumbosacral Spinal Root Avulsion by RNA Sequencing and Bioinformatics Analysis ENSG00000005339 ENSG00000006451 ENSG00000171791 ENSG00000145020 ENSG00000131828 PMC8304605__F1 Hedgehog/GLI Signaling Pathway: Transduction, Regulation, and Implications for Disease ENSG00000171791 ENSG00000128602 ENSG00000188293 PMC6820656__F5 Ovarian cancer pathway enriched by target genes of the identified miRNA biomarkers in IPA ENSG00000087245 ENSG00000107404 ENSG00000291971 ENSG00000135446 ENSG00000138798 ENSG00000100985 ENSG00000102678 ENSG00000146648 ENSG00000139687 ENSG00000116984 PMC8304605__F3 Hedgehog/GLI Signaling Pathway: Transduction, Regulation, and Implications for Disease ENSG00000168036 ENSG00000196628 PMC8692171__F1 PTEN-PI3K-AKT-mTOR pathway and therapeutic targets ENSG00000008710 ENSG00000118515 PMC4366240__F7 Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism for Chronically Activated p53 ENSG00000131473 ENSG00000198793 ENSG00000169710 ENSG00000099194 PMC4366240__F4 Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism for Chronically Activated p53 ENSG00000165119 ENSG00000113595 ENSG00000182944 ENSG00000170606 ENSG00000213853 ENSG00000111641 ENSG00000087460 ENSG00000127334 ENSG00000065613 ENSG00000180228 ENSG00000132646 ENSG00000170855 ENSG00000064692 ENSG00000288325 ENSG00000187778 PMC3570128__F2 Wnt signaling affects c-Myb stability and activity ENSG00000087095 ENSG00000064393 ENSG00000109670 PMC3588076__F3 Regulatory networks of mTOR inhibitors and miRNAs in controlling the mTOR pathway in cancer ENSG00000177169 ENSG00000163435 ENSG00000140443 PMC3588076__F2 mTOR signalling pathway ENSG00000177169 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC2760340__F2 Representation of NF1 interactions with the Ras and PI3K pathways ENSG00000198793 ENSG00000196712 PMC6168666__F3 CARD14/CARMA2 variants in keratinocytes ENSG00000114125 ENSG00000083290 ENSG00000175104 ENSG00000127191 ENSG00000121690 PMC11883231__F7 Proposed biosynthetic pathway of polyphyllins in P ENSG00000114850 ENSG00000163479 ENSG00000124783 PMC6567317__F2 Known mechanisms and signaling pathways involved in histone deacetylase inhibitor-activated induction or suppression of autophagy ENSG00000132906 ENSG00000198793 PMC6589502__F2 Generalized Lymphatic Anomaly and Gorham–Stout Disease: Overview and Recent Insights ENSG00000125266 ENSG00000124102 ENSG00000196411 ENSG00000198793 ENSG00000121879 ENSG00000150630 PMC5130266__F10 Piceatannol Attenuates Renal Fibrosis Induced by Unilateral Ureteral Obstruction via Downregulation of Histone Deacetylase 4/5 or p38-MAPK Signaling ENSG00000108840 PMC10484181__F3 Potential mechanism of P2X7R overexpression causing tumor progression ENSG00000118520 ENSG00000131196 PMC101242__F7 Up-regulation of RAD51 in 8-MOP-treated cells ENSG00000051180 PMC9359065__F1 PERK promotes immunosuppressive M2 macrophage phenotype by metabolic reprogramming and epigenetic modifications through the PERK-ATF4-PSAT1 axis ENSG00000128272 ENSG00000092621 ENSG00000113520 ENSG00000135069 PMC4058660__F2 PI3K signaling in neural aging and disease ENSG00000198793 PMC3136910__F2 Proposed model of ATF2 regulation of Ha-Ras signaling ENSG00000047410 ENSG00000162924 PMC9165365__F3 “mitochondrial stress responses”: the “Dr. Jekyll and Mr. Hyde” of neuronal disorders ENSG00000156026 ENSG00000026103 PMC3970925__F1 Activation of PPRs in cardiomyocytes by DAMPs during myocardial I/R injury ENSG00000239732 ENSG00000189403 ENSG00000136869 PMC3997674__F2 Signaling pathway of TRAIL/drug combinations ENSG00000185591 ENSG00000168610 PMC4817553__F1 The Hedgehog signalling pathway in Drosophila and vertebrates ENSG00000166813 ENSG00000128602 PMC3997674__F1 Dual opposing signaling pathways of TRAIL ENSG00000171791 ENSG00000168040 ENSG00000127191 PMC8705692__F1 Cardiac Changes in Parkinson’s Disease: Lessons from Clinical and Experimental Evidence ENSG00000123454 ENSG00000141744 PMC3470479__F1 The Genetics of Alcohol Dependence: Advancing Towards Systems-based Approaches ENSG00000130649 PMC3164695__F7 The Evolutionarily Conserved Longevity Determinants HCF-1 and SIR-2.1/SIRT1 Collaborate to Regulate DAF-16/FOXO ENSG00000146678 ENSG00000116717 ENSG00000096717 PMC8555307__F4 Toll-like receptors and toll-like receptor-targeted immunotherapy against glioma ENSG00000174123 ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC7053243__F9 Schematic diagram showing the proposed mechanism of MYC inhibition by excess BASP1 protein competing for binding to CaM ENSG00000136997 ENSG00000176788 PMC3672537__F2 Postulated interaction between the insulin signaling pathway and activation of the pro-inflammatory cascade in the pathogenesis of insulin resistance in sepsis ENSG00000170458 ENSG00000169047 ENSG00000136869 PMC6647379__F3 Tumor microenvironment influences the metabolic status of cancer cells with consequences for their metastatic potential ENSG00000135218 ENSG00000130164 ENSG00000113161 ENSG00000026103 PMC8835992__F7 Thyroid Hormone Receptor A Controls the Hind Limb Metamorphosis by Regulating Cell Proliferation and Wnt Signaling Pathways in Xenopus tropicalis ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC6912706__F2 SGA-induced impairment in hepatic insulin signaling and glucose metabolism ENSG00000150907 ENSG00000169047 PMC7003246__F2 Targeting the CD47-SIRPA pathway in cancer ENSG00000198053 PMC8213534__F1 TLR3 agonists: RGC100, ARNAX, and poly-IC: a comparative review ENSG00000102871 ENSG00000131323 ENSG00000276561 ENSG00000164342 PMC2945462__F1 Complement cascade is comprised of the Classical, Alternative, and Mannose Binding Lectin pathways ENSG00000039537 ENSG00000244731 ENSG00000166278 ENSG00000182326 ENSG00000062485 PMC6854696__F5 Schematic diagram of miR-889 regulates osteoblastic differentiation of hBMMSCs by targeting WNT7A and through Wnt Beta-catenin signaling pathway ENSG00000154764 ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC7854845__F2 UPF1 Activation in the Two Major NMD Branches ENSG00000105771 ENSG00000134815 ENSG00000151461 ENSG00000125351 ENSG00000167447 ENSG00000157106 PMC8835992__F8 Thyroid Hormone Receptor A Controls the Hind Limb Metamorphosis by Regulating Cell Proliferation and Wnt Signaling Pathways in Xenopus tropicalis ENSG00000176887 ENSG00000124766 ENSG00000168036 ENSG00000155974 ENSG00000164104 ENSG00000196628 ENSG00000198435 ENSG00000128917 ENSG00000100387 ENSG00000138380 ENSG00000164362 ENSG00000139372 ENSG00000043039 ENSG00000164690 ENSG00000143499 ENSG00000146648 ENSG00000164916 PMC2660918__F2 Hypothetical model for the end-joining mechanisms during CSR ENSG00000143799 ENSG00000149311 ENSG00000175054 ENSG00000165392 ENSG00000095002 PMC2481274__F2 Type I Interferon: Potential Therapeutic Target for Psoriasis? ENSG00000105397 ENSG00000115415 ENSG00000168310 ENSG00000125347 ENSG00000140464 PMC6034319__F3 Cross-talk between tumor, MDSCs and immune cells for development of HPV-related carcinogenesis ENSG00000108691 ENSG00000107562 ENSG00000138798 ENSG00000121966 PMC8213534__F2 TLR3 agonists: RGC100, ARNAX, and poly-IC: a comparative review ENSG00000088888 ENSG00000127666 ENSG00000164342 PMC8928433__F7 Polysaccharide From Eupolyphaga sinensis Walker With Anti-HBV Activities In Vitro and In Vivo ENSG00000172936 ENSG00000136869 PMC3268188__F2 Tumour suppressor p53 regulation and signalling ENSG00000149311 ENSG00000175054 ENSG00000048392 ENSG00000115317 ENSG00000026103 PMC8618298__F4 Current Status of Photodynamic Diagnosis for Gastric Tumors ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000256269 ENSG00000188690 ENSG00000115657 ENSG00000118777 PMC8209385__F5 Identification of Methylation-Regulated Differentially Expressed Genes and Related Pathways in Hepatocellular Carcinoma: A Study Based on TCGA Database and Bioinformatics Analysis ENSG00000114450 ENSG00000087245 ENSG00000198793 ENSG00000203710 ENSG00000185885 ENSG00000178726 ENSG00000136826 ENSG00000124216 ENSG00000178573 ENSG00000120057 ENSG00000148680 ENSG00000137265 ENSG00000107485 ENSG00000177283 ENSG00000073861 ENSG00000172201 ENSG00000175305 PMC7331465__F1 IL-7R Signaling Drives Proliferation and Survival while Preventing Premature Igk Recombination Programs During B Cell Development in Mice ENSG00000166349 ENSG00000112576 ENSG00000002330 ENSG00000150907 ENSG00000198793 ENSG00000136997 ENSG00000185658 ENSG00000171791 ENSG00000175097 ENSG00000168685 PMC6545067__F6 Graphic conclusion ENSG00000168036 PMC8039208__F4 Effects of circRNAs on the Warburg effect-associated signaling pathways ENSG00000074800 ENSG00000168610 ENSG00000159399 PMC11898978__F2 Tissue fragmentation and mechanical manipulation disrupt the ovarian Hippo signaling pathway, promoting follicle growth ENSG00000150457 ENSG00000131023 PMC8909324__F12 Biglycan Interacts with Type I Insulin-like Receptor (IGF-IR) Signaling Pathway to Regulate Osteosarcoma Cell Growth and Response to Chemotherapy ENSG00000116030 ENSG00000062485 PMC11898978__F1 PI3K/AKT signaling pathway is a key regulator of primordial follicle activation ENSG00000157404 ENSG00000198793 PMC11952802__F4 Periosteal microenvironment on P-SSCs ENSG00000133110 ENSG00000091972 ENSG00000106483 PMC10149907__F5 Regulatory mechanisms and inhibitors of isocitrate dehydrogenase 1 in cancer ENSG00000105953 PMC7789501__F2 Protein–protein interactions for the differentially expressed proteins in ApoE−/−/LDLR−/− mice (vs ENSG00000288411 ENSG00000113296 ENSG00000057593 ENSG00000126838 ENSG00000162692 ENSG00000062485 ENSG00000184500 ENSG00000148965 PMC6484007__F1 STIL: a multi-function protein required for dopaminergic neural proliferation, protection, and regeneration ENSG00000164690 ENSG00000128602 PMC4765526__F1 Cartilage matrix homeostasis is regulated dynamically by the TGFB signaling pathway ENSG00000170365 PMC4066991__F1 Missing Link between Itch and Inflammation in Atopic Dermatitis ENSG00000104321 ENSG00000167323 ENSG00000078747 ENSG00000145777 PMC6488142__F1 PI3K/Akt /mTOR pathway ENSG00000198793 PMC8483511__F3 Molecular pathways linking the CD137 signaling pathway to ECs ENSG00000170365 ENSG00000171791 ENSG00000131196 PMC8740962__F1 Proposed simplified schematic representation of SARS-CoV-2 induced intracellular pro-inflammatory signalling pathway ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC9450808__F2 Hepatocellular carcinoma: Novel understandings and therapeutic strategies based on bile acids (Review) ENSG00000276559 ENSG00000198610 ENSG00000167910 ENSG00000180432 ENSG00000117528 ENSG00000099377 ENSG00000122787 ENSG00000135929 PMC7393270__F6 Ingenuity Pathway Analysis (IPA) top regulator effect networks analysis of differentially expressed (DE) genes between Muc1−/− vs ENSG00000099985 ENSG00000135100 ENSG00000110244 ENSG00000145384 ENSG00000293532 PMC2878081__F7 Schematic overview of the pyruvate/isocitrate cycle and OGC, important components of the pathway regulating glucose- and glutamine-stimulated insulin secretion ENSG00000173599 ENSG00000079432 PMC3741284__F2 Hepatitis C Virus Induced miR200c Down Modulates FAP-1, a Negative Regulator of Src Signaling and Promotes Hepatic Fibrosis ENSG00000140262 ENSG00000147862 ENSG00000259207 ENSG00000070831 ENSG00000150093 ENSG00000166509 ENSG00000274205 ENSG00000148848 ENSG00000100290 ENSG00000168066 ENSG00000115232 ENSG00000173406 ENSG00000108639 PMC7407770__F4 Possible approaches for MASTL therapeutic targeting and the expected biological outcomes from each strategy ENSG00000128989 ENSG00000143420 ENSG00000120539 PMC8589435__F3 Canonical Wnt signalling is critical for ISC niche maintenance and is potentiated by Lgr5 ENSG00000281324 ENSG00000134982 ENSG00000108375 PMC6039345__F6 Schematic diagram showing the role of Sulfatase-1 in inhibiting mesothelin expression in Carcinogenesis ENSG00000102854 ENSG00000168610 PMC9343807__F1 Hippo–YAP/TAZ Signaling Pathway in Intestinal Self-Renewal and Regeneration After Injury ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC3014256__F3 A-Kinase Anchoring Proteins: Getting to the heart of the matter ENSG00000181788 ENSG00000108840 PMC6252330__F3 Regulators of glioma cancer stem-like quiescence in the niche ENSG00000019991 ENSG00000107562 ENSG00000138798 ENSG00000121966 PMC8555377__F3 High frequency of clonal hematopoiesis in Erdheim-Chester disease ENSG00000115524 ENSG00000157764 ENSG00000169032 PMC6252330__F1 Molecular mechanisms underlying cell cycle by cancer stem-like cells ENSG00000135446 ENSG00000250506 ENSG00000123374 ENSG00000105810 ENSG00000114315 PMC7642714__F8 C-type lectin receptor signaling pathway ENSG00000104856 ENSG00000073910 ENSG00000083799 PMC10478443__F4 Functional enrichment analysis of IGF2BP1 regulated pathways in B-ALL ENSG00000162433 ENSG00000165030 ENSG00000127528 ENSG00000010278 ENSG00000176533 ENSG00000162772 ENSG00000130935 ENSG00000164934 ENSG00000006695 ENSG00000141441 ENSG00000109084 ENSG00000198252 ENSG00000291814 ENSG00000183943 ENSG00000150907 ENSG00000142192 ENSG00000143878 ENSG00000008086 ENSG00000100100 ENSG00000189283 ENSG00000110395 ENSG00000131174 ENSG00000134824 ENSG00000149485 ENSG00000065427 ENSG00000135372 ENSG00000038945 ENSG00000184216 ENSG00000292254 ENSG00000134109 ENSG00000169136 ENSG00000099942 ENSG00000166501 ENSG00000132383 ENSG00000185591 ENSG00000026297 ENSG00000125166 ENSG00000166349 ENSG00000168209 ENSG00000130204 ENSG00000184983 ENSG00000101265 ENSG00000120705 ENSG00000176887 ENSG00000181690 ENSG00000125848 ENSG00000115956 ENSG00000011304 ENSG00000152192 ENSG00000101255 ENSG00000177606 ENSG00000167182 ENSG00000119314 ENSG00000156535 ENSG00000180815 ENSG00000189325 ENSG00000123136 ENSG00000060982 ENSG00000072274 ENSG00000186480 ENSG00000135069 ENSG00000132510 ENSG00000168961 ENSG00000134375 ENSG00000070669 ENSG00000122025 ENSG00000125249 ENSG00000122378 ENSG00000159216 ENSG00000172216 ENSG00000164938 ENSG00000291918 ENSG00000117691 ENSG00000185022 ENSG00000130826 ENSG00000110107 ENSG00000087074 ENSG00000116717 ENSG00000101811 ENSG00000167721 ENSG00000267534 ENSG00000100029 ENSG00000175166 ENSG00000173706 ENSG00000173692 ENSG00000157554 ENSG00000244509 ENSG00000059804 ENSG00000105329 ENSG00000172893 ENSG00000140983 ENSG00000109606 ENSG00000120889 ENSG00000117707 ENSG00000118971 ENSG00000166851 ENSG00000282825 ENSG00000106927 ENSG00000178607 ENSG00000136026 ENSG00000189403 ENSG00000105197 ENSG00000179094 ENSG00000213024 ENSG00000164342 ENSG00000135521 ENSG00000155090 ENSG00000183684 ENSG00000120800 ENSG00000172183 ENSG00000161956 ENSG00000115946 ENSG00000188706 ENSG00000160193 ENSG00000171848 ENSG00000184371 ENSG00000256646 ENSG00000041357 ENSG00000132341 PMC7642714__F9 IL-17 signaling pathway ENSG00000165983 ENSG00000168040 PMC5541421__F4 TREM2 signaling and function ENSG00000226275 ENSG00000173599 ENSG00000168036 ENSG00000126353 PMC3531240__F11 IFNA and LPS up-regulate APOBEC3 (A3) mRNA through different signaling pathways ENSG00000115415 ENSG00000172936 ENSG00000136869 PMC5144739__F1 Interleukin-10 (IL-10) gene transcription regulation ENSG00000172936 ENSG00000136869 ENSG00000090659 PMC6443620__F3 Hypoxia-inducible factor-1 (HIF-1) signaling pathway ENSG00000134086 ENSG00000198793 PMC5695831__F10 Schematic of pathways for transcriptional activation of Forkhead box protein O1 (FOXO1) and IGF-1 in the mouse liver ENSG00000112964 ENSG00000173757 ENSG00000150907 ENSG00000146678 PMC8234490__F8 Ergosta-7, 9 (11), 22-trien-3Beta-ol Interferes with LPS Docking to LBP, CD14, and TLR4/MD-2 Co-Receptors to Attenuate the NFKB Inflammatory Pathway In Vitro and Drosophila ENSG00000170458 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC3949135__F1 Schematic Ig synthesis pathway ENSG00000134982 ENSG00000173599 PMC7668396__F1 PI3K pathway ENSG00000157404 PMC12125839__F5 Neurodegeneration models in Parkinson’s disease: cellular and molecular paths to neuron death ENSG00000198793 ENSG00000090674 ENSG00000158828 ENSG00000112561 PMC5603960__F2 Biosynthesis of azaphilone pigments in Monascus fungi ENSG00000124610 ENSG00000184357 ENSG00000116984 PMC12125839__F2 Molecular mechanisms of mitochondrial damage involved in Parkinson's disease PMC12011818__F11 Proposed model of HPV E2-mediated suppression of innate immune signaling ENSG00000183735 ENSG00000213928 ENSG00000164430 ENSG00000088888 ENSG00000115415 ENSG00000164342 ENSG00000142166 PMC6099942__F7 DBTD decreases the intracellular TG by promoting fatty acid B oxidation and inhibiting lipogenesis through blocking the mTOR pathway ENSG00000187048 ENSG00000042832 ENSG00000161533 ENSG00000169710 PMC8730700__F3 Serum Analyte Profiles Associated With Crohn’s Disease and Disease Location ENSG00000134460 ENSG00000019991 ENSG00000107562 ENSG00000163739 ENSG00000138755 ENSG00000169429 PMC3263550__F2 Parkinson's disease pathway from the KEGG disease database ENSG00000170775 ENSG00000064692 PMC8872267__F1 Therapeutic Metabolic Reprograming Using microRNAs: From Cancer to HIV Infection PMC4560923__F2 Yeast MAPK signaling pathways are associated to hypersensitivity to cell wall stress conditions ENSG00000070831 ENSG00000197601 PMC11211258__F1 Unlocking the potential of pyroptosis in tumor immunotherapy: a new horizon in cancer treatment ENSG00000278718 ENSG00000162711 ENSG00000140968 ENSG00000163568 ENSG00000145649 ENSG00000147697 ENSG00000073605 PMC2858442__F3 Model of CD95-mediated signaling ENSG00000039537 ENSG00000062485 PMC2680672__F2 Regulation mechanisms for Itch-mediated Th2 differentiation.TCR triggering plus CD28-mediated costimulation results in the activation of MEKK1-JNK signaling pathway, which induces the serine/threonine phosphorylation of Itch ENSG00000078747 ENSG00000010810 ENSG00000131507 ENSG00000166278 PMC8289875__F2 Longitudinal genome-wide methylation study of PTSD treatment using prolonged exposure and hydrocortisone ENSG00000138193 ENSG00000196557 ENSG00000005339 ENSG00000162337 ENSG00000067606 PMC7141330__F2 Hepatitis C virus (HCV) sensing by the intracellular innate immunity throughout the virus life cycle ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000125347 ENSG00000164342 PMC6250284__F1 The nicotinamide adenine dinucleotide (NAD) synthesis pathway ENSG00000105835 ENSG00000123572 ENSG00000278488 PMC8025242__F3 Metabolism-modulating activity of IL-17 signaling in health and disease ENSG00000137033 ENSG00000127528 ENSG00000109787 ENSG00000163884 PMC4513933__F2 Summary of the interactions between the PI3K/AKT pathway and RUNX2 with integration of the TGFB pathway ENSG00000087245 ENSG00000125398 ENSG00000157227 ENSG00000019549 ENSG00000100985 ENSG00000163501 PMC6331066__F7 Model for EBV related chemoresistance.Notes: EBV activates the ATR-mediated DDR pathway, which is characterized by enhanced phosphorylation of the pathway proteins RPA32, CHK1, and H2AX ENSG00000188486 ENSG00000175054 ENSG00000051180 PMC3013518__F1 Vitamin D3 biotransformation pathway ENSG00000111012 ENSG00000019186 ENSG00000186104 ENSG00000135929 PMC2930854__F10 Ephrin-A5 and EphA5 Interaction Induces Synaptogenesis during Early Hippocampal Development ENSG00000124102 ENSG00000070831 PMC4694682__F5 Polyphenols activate Keap1/Nrf2/ARE pathway and increase the expression of detoxification/antioxidant enzymes.Notes: In the cytoplasm, Keap1 protein is always bound to Nrf2 transcription regulator and prevents its signaling ENSG00000105227 ENSG00000079999 PMC7393270__F8 Ingenuity Pathway Analysis regulator effect networks analysis of differentially expressed (DE) genes between Muc1−/− vs ENSG00000105612 ENSG00000134321 ENSG00000187608 ENSG00000269335 ENSG00000111331 ENSG00000164342 PMC7393270__F7 Ingenuity Pathway Analysis regulator effect networks analysis of differentially expressed (DE) genes between Muc1−/− vs ENSG00000138823 ENSG00000145384 ENSG00000163734 ENSG00000099194 ENSG00000132170 PMC7052940__F1 FGF/FGFR signaling pathway involved in resistance to oncotherapy ENSG00000170430 ENSG00000168610 ENSG00000146648 PMC11771116__F3 Putative pathophysiological mechanisms leading to the incidence of amyloid-related imaging abnormalities (ARIAs) in the brains of patients with Alzheimer’s disease (AD) ENSG00000288512 ENSG00000100985 ENSG00000182326 ENSG00000236625 PMC4893057__F1 Sequence elements and protein components involved in the formation of poly(A) tails ENSG00000101751 ENSG00000177084 PMC8407980__F9 Alterations and Potential Roles of MCMs in Breast Cancer ENSG00000149311 ENSG00000175054 ENSG00000069482 PMC4107319__F8 GIV/Girdin is a central hub for pro-fibrogenic signalling networks during liver fibrosis ENSG00000150907 ENSG00000136869 PMC6293652__F7 Mechanism model of PIK3CA E542K and E545K mutation-mediate regulation of proliferation and glucose metabolism via the Beta-catenin/SIRT3 in cervical cancer ENSG00000168036 ENSG00000142082 PMC8714844__F6 Recent Progress in Lymphangioma ENSG00000125266 ENSG00000196411 ENSG00000198793 ENSG00000121879 ENSG00000062485 ENSG00000150630 PMC9255545__F1 Drug targets in the IL-23–IL-17 pathway ENSG00000111537 ENSG00000177663 ENSG00000163702 PMC7697104__F1 Coupling of glucose metabolism with insulin secretion in pancreatic Beta-cell ENSG00000143158 ENSG00000135218 ENSG00000197119 ENSG00000005882 ENSG00000105953 ENSG00000175567 ENSG00000177542 ENSG00000143252 ENSG00000004864 ENSG00000182902 ENSG00000292099 ENSG00000126266 ENSG00000102743 ENSG00000146701 ENSG00000060762 PMC7918468__F4 Cellular contributors to tau-dependent degeneration ENSG00000162711 ENSG00000168329 PMC8480040__F2 Long non-coding RNA H19 in the development of osteoporosis ENSG00000178860 ENSG00000176692 ENSG00000104371 ENSG00000168036 ENSG00000184916 PMC11876172__F1 Signaling pathways and associated genes with mutations linked to hyper-IgE syndrome ENSG00000112851 ENSG00000157625 ENSG00000175104 ENSG00000168610 ENSG00000198286 PMC5928601__F3 Arachidonic acid and linoleic acid metabolism signaling pathways ENSG00000226275 ENSG00000128342 PMC10311254__F1 Unlocking the power of precision medicine for pediatric low-grade gliomas: molecular characterization for targeted therapies with enhanced safety and efficacy ENSG00000157764 ENSG00000198793 ENSG00000196712 PMC12104568__F2 CTLA‐4 mediated inhibition in T cells ENSG00000134982 ENSG00000198793 PMC8366957__F7 Quercetin Prevents Oxidative Stress-Induced Injury of Periodontal Ligament Cells and Alveolar Bone Loss in Periodontitis ENSG00000211445 ENSG00000181019 ENSG00000079999 PMC1924866__F6 Striped view of multiple data types ENSG00000105852 ENSG00000130208 ENSG00000150594 ENSG00000105854 ENSG00000134982 ENSG00000170214 ENSG00000113161 ENSG00000043591 ENSG00000274286 ENSG00000073060 ENSG00000130164 ENSG00000113749 ENSG00000285482 ENSG00000196639 PMC8114706__F7 Aging signal of C ENSG00000094631 ENSG00000136997 ENSG00000284161 ENSG00000167658 ENSG00000127580 ENSG00000096717 PMC6826402__F1 Proteomic workflow for the investigation of molecular determinants of acquired resistance to cetuximab ENSG00000204842 ENSG00000196754 ENSG00000075142 ENSG00000291971 ENSG00000105699 ENSG00000184661 ENSG00000173039 ENSG00000089157 ENSG00000138071 ENSG00000046604 ENSG00000089159 ENSG00000133216 ENSG00000168374 ENSG00000137575 ENSG00000146648 ENSG00000136068 PMC1924866__F5 Striped view of multiple time-point comparisons ENSG00000182718 ENSG00000197043 ENSG00000196975 ENSG00000122420 ENSG00000138772 ENSG00000050628 ENSG00000160013 ENSG00000125384 ENSG00000164120 ENSG00000124212 ENSG00000073756 ENSG00000168229 ENSG00000095303 ENSG00000136160 ENSG00000151617 ENSG00000160951 ENSG00000176387 PMC10531058__F2 SIRTI 1 pathway ENSG00000150907 ENSG00000096717 PMC10531058__F1 Lnc-RNAs in the Pathogenesis and Development of Diabetic Retinopathy ENSG00000169047 ENSG00000198793 PMC10531058__F4 TGFB pathway ENSG00000095739 PMC3429771__F5 Opposing roles of FGF2 and BMP4 in directing TB formation from epiblast type ES cells and iPS cells and the need to exclude FGF2 from the growth medium to minimize the co-induction of mesoderm and endoderm ENSG00000276051 PMC2230579__F10 Left, the mechanism, described by , for the proapoptotic function of TSP1 or 2 ENSG00000135218 ENSG00000291971 ENSG00000112715 ENSG00000026103 PMC10531058__F5 Nuclear factor erythroid 2 related factor 2 (NRF2) pathway ENSG00000079999 PMC11928779__F10 One carbon (1C) metabolism ENSG00000228716 ENSG00000110395 ENSG00000099810 ENSG00000123505 ENSG00000116984 PMC6904269__F3 Schematic depiction of downstream mediators of the IL-36 signaling pathway ENSG00000136696 ENSG00000136694 ENSG00000172936 PMC10215600__F1 Nrf2 and SIRT1 signaling pathways regulation by antioxidants ENSG00000087250 ENSG00000096717 ENSG00000079999 PMC3667713__F4 Molecular Rheostat at the Interface of Cancer and Diabetes ENSG00000140575 ENSG00000146648 PMC6721565__F1 Canonical WNT signaling ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000133067 ENSG00000168036 ENSG00000108375 PMC6721565__F3 LRP6 and WNT/Beta-catenin pathway alterations in epithelial cancers ENSG00000281324 ENSG00000134982 ENSG00000168036 ENSG00000108375 PMC7391798__F2 Autophagy PCR chip and KEGG PATHWAY database analysis ENSG00000110497 ENSG00000188554 ENSG00000123240 ENSG00000128272 ENSG00000116688 ENSG00000185591 ENSG00000247077 ENSG00000171109 ENSG00000135093 ENSG00000214253 PMC3484421__F2 The PI3K/Akt/mTOR pathway: Ligands binds to the receptor tyrosine kinases like EGFR, IGF1R, Her2, and Ras leads to conformational changes and activates PI3K ENSG00000002330 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC11563829__F2 Major downstream events of Trop-2 ENSG00000291971 ENSG00000137845 ENSG00000140443 PMC2660380__F3 Lysophosphatidic Acid Signaling in Airway Epithelium: Role in Airway Inflammation and Remodeling ENSG00000113070 ENSG00000198670 ENSG00000146648 PMC10539942__F1 Ferroptosis in effects of anesthetics on multiple organ diseases: A literature review ENSG00000167468 ENSG00000111684 ENSG00000168610 ENSG00000079999 PMC2886153__F1 Schematic representation of the intracellular cholesterol transport pathway ENSG00000119655 ENSG00000141458 PMC11505051__F5 Pathogenesis of inflammatory skin disease and aging by PM exposure and associated ROS signaling pathway ENSG00000115008 ENSG00000002330 ENSG00000203782 ENSG00000106546 PMC11505051__F3 Onset and exacerbation pathogenesis of chronic inflammatory respiratory disease by PM exposure and associated ROS signaling pathway ENSG00000108691 ENSG00000111537 ENSG00000113520 ENSG00000005381 ENSG00000117983 ENSG00000113525 ENSG00000277401 PMC5171696__F1 Anaplastic lymphoma kinase (ALK) signaling: Pathway figure that depicts normal activation of ALK through ligand binding ENSG00000105894 ENSG00000198793 ENSG00000177606 PMC9166621__F8 Systematic Review and Meta-Analysis of Phytoestrogen Protects Against Myocardial Ischemia/Reperfusion Injury: Pre-Clinical Evidence From Small Animal Studies ENSG00000162711 ENSG00000172046 ENSG00000136869 PMC4133204__F10 Qishenyiqi Protects Ligation-Induced Left Ventricular Remodeling by Attenuating Inflammation and Fibrosis via STAT3 and NFKB Signaling Pathway ENSG00000087245 ENSG00000100985 ENSG00000168610 PMC4391119__F6 Schematic summary of findings ENSG00000150907 PMC8589435__F4 Crosstalk between canonical and non-canonical Wnt, Hippo and Notch signalling pathways ENSG00000154342 ENSG00000281324 ENSG00000163914 ENSG00000114315 ENSG00000168646 ENSG00000155760 ENSG00000131023 ENSG00000172238 PMC6085667__F5 Compound–target network ENSG00000169710 ENSG00000171791 ENSG00000124762 ENSG00000178726 ENSG00000126218 ENSG00000164400 ENSG00000047230 ENSG00000108821 ENSG00000275565 ENSG00000120251 ENSG00000087245 ENSG00000196296 ENSG00000248144 ENSG00000050628 ENSG00000065559 ENSG00000007908 ENSG00000257335 ENSG00000102468 ENSG00000043591 ENSG00000052802 ENSG00000007171 ENSG00000132170 ENSG00000138336 ENSG00000136960 ENSG00000123989 ENSG00000006451 ENSG00000162692 ENSG00000146648 ENSG00000019991 ENSG00000152661 ENSG00000070831 ENSG00000291971 ENSG00000138798 ENSG00000140505 ENSG00000198793 ENSG00000087085 ENSG00000172572 ENSG00000255974 ENSG00000168036 ENSG00000145386 ENSG00000112715 ENSG00000196396 ENSG00000158125 ENSG00000104368 ENSG00000179295 ENSG00000180210 ENSG00000133019 ENSG00000117525 ENSG00000181019 ENSG00000149968 ENSG00000125538 ENSG00000128052 ENSG00000123374 ENSG00000170214 ENSG00000137193 ENSG00000173039 ENSG00000085662 ENSG00000002745 ENSG00000143933 ENSG00000073756 ENSG00000108691 ENSG00000111537 ENSG00000177606 ENSG00000057593 ENSG00000291748 ENSG00000187758 ENSG00000005381 ENSG00000149554 PMC4091735__F1 Evading apoptosis in cancer ENSG00000100290 ENSG00000002330 ENSG00000135116 ENSG00000104081 PMC6085667__F6 Targets of signaling pathways ENSG00000019991 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000169710 ENSG00000171791 ENSG00000145386 ENSG00000112715 ENSG00000124762 ENSG00000179295 ENSG00000149968 ENSG00000128052 ENSG00000125538 ENSG00000123374 ENSG00000108821 ENSG00000050628 ENSG00000184661 ENSG00000173039 ENSG00000137193 ENSG00000007908 ENSG00000143933 ENSG00000073756 ENSG00000043591 ENSG00000007171 ENSG00000108691 ENSG00000111537 ENSG00000177606 ENSG00000006451 ENSG00000291748 ENSG00000162692 ENSG00000149554 ENSG00000146648 PMC7598934__F6 MDA-7/IL-24-mediated inhibition in progression of PC-induced bone metastasis through modulation of the bone microenvironment ENSG00000162892 ENSG00000131196 PMC3155297__F1 General and organelle-specific stress response pathways influenced by the ageing process ENSG00000284774 ENSG00000144895 PMC8712697__F3 Comparative Genomic Analysis of Labrenzia aggregata (Alphaproteobacteria) Strains Isolated From the Mariana Trench: Insights Into the Metabolic Potentials and Biogeochemical Functions ENSG00000125814 PMC5536000__F5 Schematic of the miR-206 regulatory mechanism during adipogenesis ENSG00000168036 PMC2700405__F1 The canonical Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9414397__F4 Protein-Based Adjuvants for Vaccines as Immunomodulators of the Innate and Adaptive Immune Response: Current Knowledge, Challenges, and Future Opportunities ENSG00000183735 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC3136489__F10 Pathways Activated during Human Asthma Exacerbation as Revealed by Gene Expression Patterns in Blood ENSG00000095585 ENSG00000002330 ENSG00000198793 ENSG00000197943 ENSG00000132478 ENSG00000010671 PMC4431773__F1 Anti-HCV drugs targeting viral life cycle ENSG00000110651 PMC9045034__F3 Anti-tuberculosis drug candidate pipeline and mechanism of drug action PMC3136489__F11 Pathways Activated during Human Asthma Exacerbation as Revealed by Gene Expression Patterns in Blood ENSG00000291603 ENSG00000107338 ENSG00000213658 ENSG00000276559 ENSG00000155926 ENSG00000010810 ENSG00000113263 ENSG00000135605 PMC5362574__F8 Suggested model ENSG00000111537 ENSG00000115415 ENSG00000291971 PMC4951198__F10 Molecular and physiological defects in mice lacking BRAF and RAF1 in the epidermis ENSG00000150782 ENSG00000157764 ENSG00000108688 ENSG00000113520 ENSG00000145777 ENSG00000113525 PMC9318090__F2 Scheme of molecules and pathways involved in DR and their relationship ENSG00000167772 ENSG00000281324 ENSG00000130173 PMC2840217__F7 Changes in cell cycle regulation in response to MG132 (A), methylmercury (MeHg, B), and cadmium (Cd, C) in MEF cells ENSG00000149311 ENSG00000131747 ENSG00000149554 ENSG00000139687 PMC6203794__F1 Tumor-induced CD8+ Treg cells and their potential role in tumor microenvironment ENSG00000163599 ENSG00000049768 PMC2840217__F6 Antioxidant and phase II detoxifying enzyme genes in response to MG132 (A), methylmercury (MeHg, B), and cadmium (Cd, C) in MEF cells ENSG00000102145 ENSG00000284816 ENSG00000110711 ENSG00000178573 ENSG00000156127 ENSG00000111837 ENSG00000177606 ENSG00000187837 ENSG00000172005 ENSG00000113520 ENSG00000079999 ENSG00000167701 PMC2840217__F9 Parkinson's disease (PD)-related gene pathway in response to MG132, methylmercury (MeHg), and cadmium (Cd) in MEF cells ENSG00000132906 ENSG00000166167 ENSG00000166233 ENSG00000170775 ENSG00000198833 ENSG00000036672 ENSG00000112530 ENSG00000064692 ENSG00000134588 ENSG00000143258 ENSG00000164305 ENSG00000122042 PMC5412884__F1 Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease ENSG00000154342 ENSG00000128917 ENSG00000134982 ENSG00000138798 ENSG00000168036 ENSG00000133961 ENSG00000146648 PMC6254660__F7 Cytotoxicity of nimbolide towards multidrug-resistant tumor cells and hypersensitivity via cellular metabolic modulation ENSG00000198793 ENSG00000136997 ENSG00000184207 PMC3830525__F4 Rho GTPases control specific cytoskeleton-dependent functions of hematopoietic stem cells ENSG00000070831 ENSG00000111540 PMC5866434__F2 Effect of CO on cellular inflammation pathways ENSG00000162711 ENSG00000136869 PMC2840217__F8 Alteration in Ubiquitin-Proteasome System (UPS) in response to MG132 (A), methylmercury (MeHg, B), and cadmium (Cd, C) in MEF cells ENSG00000167653 PMC8465636__F6 Omega-3 Fatty Acids DHA and EPA Reduce Bortezomib Resistance in Multiple Myeloma Cells by Promoting Glutathione Degradation ENSG00000065911 ENSG00000128272 ENSG00000162772 ENSG00000146733 PMC11913833__F10 Regulation network by ACS on the innate and adaptive immune systems of young rabbits ENSG00000162711 ENSG00000167207 ENSG00000134982 ENSG00000136869 ENSG00000106100 PMC9600461__F3 Boosting Neurogenesis in the Adult Hippocampus Using Antidepressants and Mesenchymal Stem Cells ENSG00000178860 ENSG00000154342 ENSG00000164879 ENSG00000188064 ENSG00000277641 ENSG00000125084 PMC9213082__F8 Activated AXL Protects Against Hepatic Ischemia-reperfusion Injury by Upregulating SOCS-1 Expression ENSG00000167601 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC4007596__F2 Cytoscape plugin was used to analyze within Balb/c up-regulated genes, genes interaction within the same pathway and across different pathways ENSG00000177606 ENSG00000197386 PMC8743723__F8 Long non-coding RNA AC122108.1 promotes lung adenocarcinoma brain metastasis and progression through the Wnt/Beta-catenin pathway by directly binding to aldolase A ENSG00000137673 ENSG00000134982 ENSG00000168036 PMC4671322__F1 Molecular mechanisms underlying the oncogenic metabolic phenotype ENSG00000198793 ENSG00000136997 ENSG00000146648 ENSG00000140443 PMC4007596__F3 Cytoscape plugin was used to analyse within C57Bl/6 up-regulated genes, genes interaction within the same pathway and across different pathways ENSG00000109390 ENSG00000198793 PMC4530889__F7 Dysregulation of the Transforming Growth Factor B Pathway in Induced Pluripotent Stem Cells Generated from Patients with Diamond Blackfan Anemia PMC9687381__F2 Interplay between Finasteride-Induced Androgen Imbalance, Endoplasmic Reticulum Stress, Oxidative Stress, and Liver Disorders in Paternal and Filial Generation ENSG00000100219 PMC4214431__F1 Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut ENSG00000169554 ENSG00000122691 PMC5744080__F8 GF1 mechanism of preventing ox-LDL-induced inflammatory injuries through activating A20-mediated NFKB signal pathway ENSG00000136869 PMC3733962__F1 Proteomic Analysis of Signaling Network Regulation in Renal Cell Carcinomas with Differential Hypoxia-Inducible Factor-2A Expression ENSG00000115484 ENSG00000143514 ENSG00000170027 ENSG00000143815 ENSG00000130147 ENSG00000130402 ENSG00000116584 ENSG00000185651 ENSG00000177600 ENSG00000136108 PMC8435533__F7 Schematic figure showing EMP3 signaling pathway ENSG00000142227 ENSG00000198793 ENSG00000275272 PMC8071327__F1 Sphingolipid metabolism and compartmentalization ENSG00000113163 PMC4309684__F8 Inactivation of Sag/Rbx2/Roc2 E3 Ubiquitin Ligase Triggers Senescence and Inhibits Kras-Induced Immortalization ENSG00000113558 ENSG00000285246 ENSG00000109670 PMC8071327__F5 SphK1 and S1P signaling in colorectal carcinogenesis and progression ENSG00000157933 ENSG00000168610 PMC5628093__F2 Crosstalk between Panx1 and ligand-gated receptor channels ENSG00000291971 ENSG00000166278 ENSG00000110218 PMC4370098__F7 Signalling mechanisms regulating phenotypic changes in breast cancer cells ENSG00000131473 ENSG00000291971 ENSG00000198793 ENSG00000166278 PMC4466682__F9 EGF-reduced Wnt5a transcription induces epithelial-mesenchymal transition via Arf6-ERK signaling in gastric cancer cells ENSG00000138798 ENSG00000165527 ENSG00000146648 PMC5907632__F1 Etirinotecan pegol metabolic pathway ENSG00000134982 PMC5318911__F7 Identification of miRNA-mRNA Modules in Colorectal Cancer Using Rough Hypercuboid Based Supervised Clustering ENSG00000132906 ENSG00000002330 ENSG00000134982 ENSG00000163914 ENSG00000168036 ENSG00000164305 PMC6406581__F3 Mammalian target of rapamycin (mTOR) pathway ENSG00000177169 ENSG00000155792 ENSG00000186654 ENSG00000132170 PMC6277783__F2 Schematic representation of various processes during seed filling stage in both monocot (top left) as well as dicot (top right) plants ENSG00000090402 ENSG00000167701 PMC3721368__F1 Schematic depicting the canonical and noncanonical TGFB signaling systems coupled to EMT in MECs ENSG00000291971 ENSG00000198742 ENSG00000198793 ENSG00000168610 PMC7013724__F3 Mitochondria unfolded protein response (UPRmt) ENSG00000128272 ENSG00000125656 PMC2882865__F2 Transcriptional regulation by E2F complexes modulates cell-cycle control, cell fate, and survival ENSG00000101945 ENSG00000148400 PMC7899890__F6 Interaction between tumor necrosis factor and tumor necrosis factor receptor 2 signaling ENSG00000078747 ENSG00000102871 ENSG00000007908 ENSG00000168040 ENSG00000168404 ENSG00000164305 PMC2692221__F1 BER subpathways for damaged bases and DNA strand breaks ENSG00000132646 PMC2777383__F1 Predictive Phosphorylation Signature of Lung Cancer ENSG00000132906 ENSG00000152661 ENSG00000002330 ENSG00000291971 ENSG00000198793 ENSG00000177606 ENSG00000136997 ENSG00000168610 ENSG00000146648 ENSG00000089159 PMC10299596__F1 BCR signaling pathway and BTKis resistance in CLL ENSG00000095585 ENSG00000291971 ENSG00000186716 ENSG00000198793 ENSG00000197943 ENSG00000010671 PMC2906469__F3 Progressive inactivation of GSK3B may promote increased anti-apoptosis and oral cancer ENSG00000171791 ENSG00000168040 PMC11992733__F6 Targeting PRDX2 to inhibit tumor growth and metastasis in triple-negative breast cancer: the role of FN1 and the PI3K/AKT/SP1 pathway ENSG00000185591 PMC2906469__F4 Targeting GSK3B pathway may be highly beneficial for curing oral cancer ENSG00000134982 ENSG00000198793 ENSG00000146648 PMC8355588__F5 Atrial Natriuretic Peptide Inhibited ABCA1/G1-dependent Cholesterol Efflux Related to Low HDL-C in Hypertensive Pregnant Patients ENSG00000160179 PMC8069026__F1 Illustration of the metabolism of galactose through the Leloir pathway ENSG00000069482 ENSG00000165434 ENSG00000169299 PMC7501700__F6 AD-integrated pathway and functional modules ENSG00000070831 ENSG00000102871 ENSG00000138798 ENSG00000198793 ENSG00000169047 ENSG00000173039 ENSG00000143933 ENSG00000213341 ENSG00000112715 ENSG00000127191 ENSG00000169291 ENSG00000074800 ENSG00000177606 ENSG00000166501 ENSG00000136869 ENSG00000175104 ENSG00000146648 PMC7406690__F2 Role of YAP/TAZ in Cell Lineage Fate Determination and Related Signaling Pathways ENSG00000149930 ENSG00000160551 ENSG00000135090 ENSG00000144560 ENSG00000197905 ENSG00000114978 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC8699889__F8 Prognostic and Genomic Analysis of Proteasome 20S Subunit Alpha (PSMA) Family Members in Breast Cancer ENSG00000111537 ENSG00000134982 ENSG00000291814 PMC8699889__F7 Prognostic and Genomic Analysis of Proteasome 20S Subunit Alpha (PSMA) Family Members in Breast Cancer ENSG00000140564 ENSG00000139192 ENSG00000134982 ENSG00000205220 ENSG00000149311 ENSG00000175054 ENSG00000112977 ENSG00000111537 ENSG00000141279 ENSG00000001626 ENSG00000119912 ENSG00000089597 ENSG00000185825 PMC8699889__F6 Prognostic and Genomic Analysis of Proteasome 20S Subunit Alpha (PSMA) Family Members in Breast Cancer ENSG00000117054 ENSG00000163541 ENSG00000100219 ENSG00000120437 ENSG00000172340 ENSG00000117305 PMC8699889__F5 Prognostic and Genomic Analysis of Proteasome 20S Subunit Alpha (PSMA) Family Members in Breast Cancer ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000134982 ENSG00000135446 ENSG00000113558 ENSG00000123374 ENSG00000099804 ENSG00000115419 ENSG00000132341 PMC10708062__F10 Analysis of DEGs involved in citrate cycle pathway in roots under osmotic stress ENSG00000131473 ENSG00000143252 ENSG00000073578 ENSG00000117118 ENSG00000173599 ENSG00000105953 ENSG00000146701 ENSG00000062485 PMC3286397__F11 Campylobacter jejuni-induced Cdc42 activation ENSG00000070831 ENSG00000291971 ENSG00000163914 ENSG00000146648 PMC9033871__F3 Inflammation and atherosclerosis: signaling pathways and therapeutic intervention ENSG00000278718 ENSG00000174125 ENSG00000162711 ENSG00000183735 ENSG00000226275 ENSG00000172936 ENSG00000131323 ENSG00000150455 ENSG00000276561 ENSG00000184216 ENSG00000169174 PMC4364658__F1 MiRNA targeted signaling pathways in four different important cells including plaque macrophage, platelet, monocyte and endothelial cell ENSG00000145604 ENSG00000134982 ENSG00000163914 ENSG00000146648 PMC11043956__F7 SSYYJN ameliorates CKD-induced muscle atrophy by inhibiting ferroptosis in tibialis anterior muscle cell via HIF-1A/SLC7A11 pathway ENSG00000168003 ENSG00000151012 ENSG00000167468 PMC7212757__F1 Role of Excitatory Cerebellar Nucleocortical Circuit in controlling associative motor learning ENSG00000173599 ENSG00000062485 PMC3461933__F1 Looking in the miR-ror: TGFB–mediated activation of NFKB in glioma ENSG00000100906 ENSG00000138798 ENSG00000128342 ENSG00000146648 ENSG00000125968 PMC4364658__F6 MiRNA targeted upregulated genes of Rho GTPase signaling ENSG00000132694 ENSG00000104880 ENSG00000160145 ENSG00000102606 ENSG00000186517 ENSG00000143878 ENSG00000100852 ENSG00000196220 ENSG00000146192 ENSG00000136002 ENSG00000284984 ENSG00000131089 ENSG00000024526 ENSG00000139725 ENSG00000163914 ENSG00000171680 ENSG00000196914 ENSG00000072422 PMC3533285__F11 SMRT-GPS2 corepressor pathway dysregulation coincides with obesity-linked adipocyte inflammation ENSG00000081041 ENSG00000122691 ENSG00000288325 PMC3434350__F1 Translational impact of the mTOR signaling pathway ENSG00000026508 PMC8699889__F9 Prognostic and Genomic Analysis of Proteasome 20S Subunit Alpha (PSMA) Family Members in Breast Cancer ENSG00000125817 ENSG00000110514 ENSG00000117697 ENSG00000145241 ENSG00000134982 ENSG00000117399 ENSG00000149503 PMC3759360__F2 When Ubiquitin Meets NFKB: A trove for anti-cancer drug development ENSG00000143799 ENSG00000104856 ENSG00000149311 ENSG00000101751 ENSG00000131323 ENSG00000175104 PMC8093449__F2 In silico Gene Set and Pathway Enrichment Analyses Highlight Involvement of Ion Transport in Cholinergic Pathways in Autism: Rationale for Nutritional Intervention ENSG00000087085 ENSG00000080709 PMC9361019__F6 Stemness Analysis Uncovers That The Peroxisome Proliferator-Activated Receptor Signaling Pathway Can Mediate Fatty Acid Homeostasis In Sorafenib-Resistant Hepatocellular Carcinoma Cells ENSG00000180432 ENSG00000099194 PMC3953890__F1 EGFR-axis pathway that contributes to cyst formation and progressive enlargement in ADPKD and ARPKD ENSG00000163235 ENSG00000113070 PMC9266896__F1 Interleukin 15 in Cell-Based Cancer Immunotherapy ENSG00000105639 ENSG00000168610 PMC4272425__F9 Proposed model of Pofut1 involvement in commitment of myogenically differentiated cells through activation of the Notch signaling pathway ENSG00000009709 ENSG00000101346 ENSG00000198125 PMC7912342__F6 CGAS-STING signaling pathway ENSG00000164430 PMC6090282__F13 Signaling pathways activated by temozolomide in glioma cells ENSG00000144935 ENSG00000291971 ENSG00000198793 ENSG00000177606 ENSG00000170430 PMC6331329__F5 InterferonG regulates cell malignant growth via the c-Abl/HDAC2 signaling pathway in mammary epithelial cells ENSG00000135446 ENSG00000196591 PMC7912342__F5 NLRP3 Inflammasomes signaling pathway ENSG00000162711 ENSG00000164430 ENSG00000125538 ENSG00000089041 PMC7912342__F4 RLR signaling pathway ENSG00000131323 ENSG00000168040 ENSG00000276561 PMC8093449__F5 In silico Gene Set and Pathway Enrichment Analyses Highlight Involvement of Ion Transport in Cholinergic Pathways in Autism: Rationale for Nutritional Intervention ENSG00000111262 ENSG00000157764 ENSG00000152495 ENSG00000182324 ENSG00000291971 ENSG00000127955 ENSG00000087085 ENSG00000132639 ENSG00000187688 ENSG00000148408 ENSG00000101438 ENSG00000165646 ENSG00000196689 ENSG00000157542 PMC3845018__F3 Graft-versus-host disease signaling pathway and miRNA interactions obtained using IPA ENSG00000169245 ENSG00000019991 ENSG00000175104 PMC7912342__F1 Toll-like receptor (TLR) dependent signaling pathways ENSG00000174123 ENSG00000102871 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000172005 ENSG00000157625 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC4364457__F3 MicroRNAs Are Part of the Regulatory Network that Controls EGF Induced Apoptosis, Including Elements of the JAK/STAT Pathway, in A431 Cells ENSG00000123416 ENSG00000120438 ENSG00000146731 ENSG00000092820 ENSG00000175334 PMC8233862__F4 Osteocyte Dysfunction in Joint Homeostasis and Osteoarthritis ENSG00000178860 ENSG00000198793 PMC4386978__F1 Extracellular signalling molecules in the ischaemic/reperfused heart – druggable and translatable for cardioprotection? ENSG00000096088 ENSG00000168610 PMC6456305__F6 GPs unmask cryptic variation in parallel signaling pathways and subpathways ENSG00000196511 ENSG00000168066 PMC9684800__F4 Roles of metabolic profiles and intracellular signaling pathways of tumor microenvironment cells in angiogenesis of solid tumors ENSG00000196411 ENSG00000170365 ENSG00000291971 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000184216 ENSG00000125968 ENSG00000163217 PMC3749846__F3 Role of DMP1 and its future in lung cancer diagnostics ENSG00000135446 ENSG00000177606 ENSG00000136997 ENSG00000152592 PMC8790423__F2 Statin as a therapeutic agent in gastroenterological cancer ENSG00000157554 PMC9101507__F4 Endocytosis at the Crossroad of Polarity and Signaling Regulation: Learning from Drosophila melanogaster and Beyond ENSG00000138798 ENSG00000146648 ENSG00000111737 PMC8790423__F1 Statin as a therapeutic agent in gastroenterological cancer ENSG00000112972 ENSG00000130164 ENSG00000113161 ENSG00000169710 PMC6986441__F1 Canonical pathway (Modified from IPA) for Opioid Signaling [−log(P-value) = 8.48; Z-score = 0.392] ENSG00000124140 ENSG00000125740 ENSG00000002330 ENSG00000157764 ENSG00000136997 ENSG00000168036 ENSG00000160710 ENSG00000166278 ENSG00000198125 PMC9559516__F5 RKIP in the Regulation of EMT in the Tumor Microenvironment ENSG00000110400 ENSG00000119888 PMC6986441__F3 Canonical pathway (Modified from IPA) for Dopamine Receptor Signaling [−log(P-value) = 2.97; Z-score = 1.89] ENSG00000180720 ENSG00000152266 ENSG00000089692 ENSG00000130643 ENSG00000110492 ENSG00000164326 ENSG00000115138 ENSG00000281931 ENSG00000082556 PMC4441763__F4 Quantifying Ubiquitin Signaling ENSG00000036672 ENSG00000116688 ENSG00000158828 ENSG00000154124 ENSG00000143258 PMC6986441__F2 Canonical pathway (Modified from IPA) for Corticotropin Releasing Hormone Signaling [−log(P-value) = 3.74; Z-score = 1.29] ENSG00000073060 ENSG00000069482 ENSG00000169427 ENSG00000167768 ENSG00000164326 ENSG00000148926 ENSG00000163794 ENSG00000177606 ENSG00000120088 ENSG00000115138 ENSG00000164690 ENSG00000185149 PMC8303227__F1 Exploiting DNA Damage Repair in Precision Cancer Therapy: BRCA1 as a Prime Therapeutic Target ENSG00000012061 ENSG00000083093 ENSG00000154920 ENSG00000188827 ENSG00000039650 ENSG00000310560 ENSG00000139618 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000105486 ENSG00000169621 ENSG00000134574 ENSG00000113318 ENSG00000165392 ENSG00000197299 ENSG00000177084 ENSG00000095002 ENSG00000138385 ENSG00000122512 ENSG00000156273 PMC3279943__F1 PI3K and STAT3: a New Alliance ENSG00000168610 PMC7601167__F1 Graphical abstract depicting the mechanisms of inherent and acquired resistance to PI3K inhibition at different vertical nodes along the PI3K/Akt/mTOR pathway ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000121879 PMC4936558__F6 Genes up- and downstream of flavonol biosynthesis are also affected in the Δy mutants ENSG00000183625 ENSG00000100577 ENSG00000121807 PMC11721291__F7 CGAS/STING activity ENSG00000164430 PMC4113246__F3 Gene Regulatory Networks in Cardiac Conduction System Development ENSG00000138622 ENSG00000135111 ENSG00000164093 ENSG00000168779 ENSG00000089225 PMC6986441__F5 Canonical pathway (Modified from IPA) for GABA Receptor Signaling [−log(P-value) = 5.07; Z-score = NaN] ENSG00000143149 ENSG00000171723 ENSG00000101438 ENSG00000268089 ENSG00000135018 PMC8557524__F3 Targeting CD47 for cancer immunotherapy ENSG00000198053 ENSG00000015285 PMC9316483__F2 Study on the Molecular Mechanism of High Altitude Heart Disease in Children ENSG00000167772 ENSG00000151617 ENSG00000166135 PMC6986441__F4 Canonical pathway (Modified from IPA) for Serotonin Signaling [−log(P-value) = 2.04; Z-score = NaN] ENSG00000116096 PMC1936363__F1 Epidermal growth factor receptor pathway ENSG00000002330 ENSG00000005882 ENSG00000198793 PMC8481641__F2 Immunoregulatory Role of the Signal Regulatory Protein Family and CD47 Signaling Pathway in Type 1 Diabetes ENSG00000291603 ENSG00000111537 ENSG00000198053 ENSG00000180644 PMC5422340__F4 TGFB1-mediated regulatory network via Ingenuity pathway analysis ENSG00000100906 ENSG00000109320 ENSG00000173039 ENSG00000092067 ENSG00000185591 ENSG00000168610 PMC6637653__F7 Breast cancer cell-based pathobiochemical pathways showing LPHN-induced activation of PKCA, which triggers the translocation of Tim-3 and galectin-9 onto the cell surface which is required for immune escape ENSG00000125848 ENSG00000159224 PMC5422340__F3 P53-mediated regulatory network via Ingenuity pathway analysis ENSG00000172216 ENSG00000100906 ENSG00000177606 ENSG00000173039 ENSG00000168036 ENSG00000221869 ENSG00000185591 ENSG00000168610 PMC8660623__F8 Bone morphogenetic protein 9 enhances osteogenic and angiogenic responses of human amniotic mesenchymal stem cells cocultured with umbilical vein endothelial cells through the PI3K/AKT/m-TOR signaling pathway ENSG00000170365 ENSG00000110799 ENSG00000198793 PMC4619170__F7 Even-skipped+ interneurons are core components of a sensorimotor circuit that maintains left-right symmetric muscle contraction amplitude ENSG00000175054 PMC8303227__F4 Exploiting DNA Damage Repair in Precision Cancer Therapy: BRCA1 as a Prime Therapeutic Target ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000136492 ENSG00000083093 ENSG00000113456 ENSG00000123374 ENSG00000051180 ENSG00000138385 ENSG00000139618 PMC5988934__F1 Activation of antiviral innate immunity in CHB ENSG00000239732 ENSG00000172936 ENSG00000276561 PMC1176468__F9 Crosstalk model of ATF3 and c-myc in serum induction ENSG00000291971 ENSG00000162772 PMC7588667__F4 DNA damage response in amyotrophic lateral sclerosis ENSG00000143799 ENSG00000149311 ENSG00000204842 ENSG00000163961 ENSG00000155636 ENSG00000284099 ENSG00000165280 ENSG00000112130 PMC4782221__F5 SYK tyrosine kinase: a crucial player in diverse biological functions ENSG00000170909 ENSG00000197943 PMC5192357__F1 Action of blockade of inhibitory pathways or activation of costimulatory pathways to promote CD8+T cell priming after vaccination ENSG00000163599 ENSG00000049768 PMC10136857__F1 Canonical and non-canonical Wnt signaling pathways in cholangiocytes and the role of the primary cilia in modulating these pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC10534279__F4 Growth differentiation factor 15 in cancer cachexia (Review) ENSG00000108691 ENSG00000187871 ENSG00000115138 ENSG00000145321 ENSG00000168610 ENSG00000173327 ENSG00000130513 PMC10534279__F3 Growth differentiation factor 15 in cancer cachexia (Review) ENSG00000170365 ENSG00000187871 ENSG00000198793 ENSG00000130513 PMC11528463__F7 BC-derived CAV1 promoting BC lung metastasis ENSG00000162711 ENSG00000108691 ENSG00000291971 ENSG00000136869 ENSG00000168484 ENSG00000100985 PMC5733215__F4 STAT3/S1P/S1PR1/SPHK1/SPL-positive feed-forward loop promoting CAC ENSG00000170989 ENSG00000083799 ENSG00000168610 ENSG00000183018 PMC8909868__F3 Ca2+ Transportome and the Interorganelle Communication in Hepatocellular Carcinoma ENSG00000137672 ENSG00000168610 PMC3581520__F1 Differential Intrahepatic Phospholipid Zonation in Simple Steatosis and Nonalcoholic Steatohepatitis ENSG00000087253 ENSG00000110721 ENSG00000100288 ENSG00000173599 ENSG00000291994 ENSG00000111684 ENSG00000153395 ENSG00000133027 PMC8909868__F2 Ca2+ Transportome and the Interorganelle Communication in Hepatocellular Carcinoma ENSG00000087245 ENSG00000148400 ENSG00000170558 ENSG00000142082 ENSG00000079999 PMC12066790__F9 Oncogenic mechanisms of EBV in lymphoma ENSG00000197635 ENSG00000100906 ENSG00000181847 ENSG00000015285 ENSG00000232326 ENSG00000115009 ENSG00000106459 PMC12066790__F6 Oncogenic mechanisms of HPV in cervical cancer ENSG00000138798 ENSG00000168036 ENSG00000205250 ENSG00000168040 ENSG00000175054 ENSG00000108691 ENSG00000164430 ENSG00000137077 ENSG00000136997 ENSG00000015285 ENSG00000164362 ENSG00000146648 ENSG00000026103 PMC9323628__F3 Deubiquitinases in Cancers: Aspects of Proliferation, Metastasis, and Apoptosis ENSG00000124422 ENSG00000163930 ENSG00000152484 ENSG00000291527 ENSG00000102226 ENSG00000172046 ENSG00000136997 ENSG00000134588 ENSG00000146648 ENSG00000101557 PMC12066790__F5 Oncogenic mechanisms of EBV in gastric cancer ENSG00000102962 ENSG00000087245 ENSG00000163939 ENSG00000002330 ENSG00000134982 ENSG00000168036 ENSG00000146457 ENSG00000112715 ENSG00000121879 ENSG00000140297 ENSG00000168610 ENSG00000137801 ENSG00000134086 ENSG00000089692 ENSG00000088247 ENSG00000100985 ENSG00000163501 ENSG00000140443 ENSG00000168772 PMC6396132__F3 Hedgehog signaling and Wnt signaling in the primary cilium ENSG00000104290 ENSG00000168036 ENSG00000128602 PMC7825432__F3 Glycolysis reactions and the reactions of encapsulated enzymes (GDH + AAT) in erythrocyte ENSG00000112977 PMC12066790__F7 Oncogenic mechanisms of EBV in nasopharyngeal carcinoma ENSG00000102962 ENSG00000002330 ENSG00000151012 ENSG00000138772 ENSG00000198793 ENSG00000047936 ENSG00000168610 ENSG00000106546 ENSG00000079999 ENSG00000175054 ENSG00000118503 ENSG00000167468 ENSG00000146648 ENSG00000159399 PMC12066790__F4 Oncogenic mechanisms of HBV and HCV in hepatocellular carcinoma ENSG00000105329 ENSG00000163599 ENSG00000168036 ENSG00000265972 ENSG00000081051 ENSG00000168610 ENSG00000198887 ENSG00000164362 ENSG00000189403 ENSG00000123374 ENSG00000146648 ENSG00000159399 ENSG00000026103 PMC8705881__F1 MicroRNAs Regulate Cell Cycle and Cell Death Pathways in Glioblastoma ENSG00000136868 ENSG00000135446 ENSG00000198793 ENSG00000170430 ENSG00000105810 ENSG00000100985 ENSG00000168610 ENSG00000146648 PMC7820019__F8 Alt-RPL36 downregulates the PI3K-AKT-mTOR signaling pathway by interacting with TMEM24 ENSG00000198793 ENSG00000166278 PMC3328827__F2 Beyond inactivation of the MEN1 gene, additional mutations in other genes may be responsible for acceleration of tumor growth, thus involving a process of multistep tumorigenesis ENSG00000198793 ENSG00000177606 ENSG00000136997 ENSG00000168036 PMC7334796__F6 Distribution of partial targets of ATR and CR on the compressed pathway ENSG00000104365 ENSG00000171105 ENSG00000102871 ENSG00000130522 ENSG00000213341 ENSG00000171791 ENSG00000112715 ENSG00000164305 ENSG00000102468 ENSG00000122025 ENSG00000133019 ENSG00000175054 ENSG00000128052 ENSG00000175104 PMC3851046__F7 Proposed molecular mechanism for the inhibitory effects of zinc on RANKL-induced osteoclastogenesis ENSG00000170909 ENSG00000101307 ENSG00000293604 ENSG00000175104 ENSG00000131196 PMC11173094__F3 Natural products that modulate specific proteins in the molecular pathway of inducing and inhibiting ferroptosis ENSG00000087510 ENSG00000101460 ENSG00000156709 ENSG00000072274 ENSG00000181867 ENSG00000162772 ENSG00000057663 ENSG00000136381 ENSG00000168003 ENSG00000185591 ENSG00000179148 ENSG00000161905 ENSG00000138449 ENSG00000151012 ENSG00000197635 ENSG00000116044 ENSG00000018408 ENSG00000135245 ENSG00000108839 ENSG00000128272 ENSG00000069869 ENSG00000167468 ENSG00000111684 ENSG00000167996 ENSG00000042286 ENSG00000110911 ENSG00000127948 PMC3383648__F1 Vismodegib ENSG00000106571 ENSG00000117425 ENSG00000164161 ENSG00000128602 PMC5795664__F4 Mutations in various genes in the JAK/STAT pathway (MPL, CRLF2, JAK1, JAK3, JAK2, LNK, SOCS1, STAT3) implicated in hematologic malignancies ENSG00000117400 ENSG00000292363 ENSG00000105639 ENSG00000168610 PMC5893443__F8 Dual Catenin Loss in Murine Liver Causes Tight Junctional Deregulation and Progressive Intrahepatic Cholestasis ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC9326561__F4 Integrative Proteomic and Phosphoproteomic Analyses of Hypoxia-Treated Pulmonary Artery Smooth Muscle Cells ENSG00000140992 ENSG00000092201 ENSG00000136897 ENSG00000072274 ENSG00000159210 ENSG00000106638 ENSG00000204822 ENSG00000091009 ENSG00000164877 ENSG00000169895 ENSG00000108561 ENSG00000204262 ENSG00000196531 ENSG00000065833 ENSG00000173599 ENSG00000047230 ENSG00000108821 ENSG00000159335 ENSG00000119705 ENSG00000136045 ENSG00000130826 ENSG00000170348 ENSG00000145220 ENSG00000100632 ENSG00000096080 ENSG00000111799 ENSG00000114054 ENSG00000135372 ENSG00000108344 ENSG00000074410 ENSG00000163605 ENSG00000100034 ENSG00000175220 ENSG00000163739 ENSG00000197746 ENSG00000176788 ENSG00000112304 ENSG00000197958 ENSG00000113593 ENSG00000214063 ENSG00000108256 ENSG00000162664 ENSG00000175110 ENSG00000024422 ENSG00000100603 ENSG00000102390 ENSG00000107929 ENSG00000132463 ENSG00000113140 ENSG00000198931 ENSG00000134871 ENSG00000140416 ENSG00000221823 ENSG00000122566 ENSG00000065978 ENSG00000134247 ENSG00000167772 ENSG00000175416 ENSG00000135387 ENSG00000090581 ENSG00000168264 ENSG00000291748 ENSG00000167996 ENSG00000034510 ENSG00000100348 ENSG00000122705 ENSG00000159399 ENSG00000111642 PMC9316001__F2 Anticancer Effects and Mechanisms of Berberine from Medicinal Herbs: An Update Review ENSG00000135446 ENSG00000170558 ENSG00000198793 ENSG00000168036 ENSG00000168610 ENSG00000146648 ENSG00000274473 PMC3399091__F1 PAK1 Molecular Pathway ENSG00000002330 ENSG00000149269 PMC5108321__F9 The working model of AMDE-1-induced canonical and noncanonical LC3 lipidation ENSG00000177169 ENSG00000152348 ENSG00000115271 ENSG00000157954 ENSG00000145782 ENSG00000057663 PMC4842122__F1 Signaling pathways involved in SSc pathogenesis that may also play a role in EndoMT ENSG00000148400 ENSG00000164690 ENSG00000128602 PMC8302073__F1 Live Cell Imaging of Nuclear Actin Filaments and Heterochromatic Repair foci in Drosophila and Mouse Cells ENSG00000149311 ENSG00000198887 ENSG00000197299 ENSG00000051180 ENSG00000061656 PMC2494567__F10 Grainyhead-like factor Get1/Grhl3 regulates formation of the epidermal leading edge during eyelid closure ENSG00000163235 ENSG00000182093 ENSG00000146648 PMC8490739__F7 SMYD3/ITGB6/TGFB1 Positive Feedback Loop Promotes the Invasion and Adhesion of Ovarian Cancer Spheroids ENSG00000105329 ENSG00000170558 ENSG00000115221 PMC8194669__F2 Karyopherin abnormalities in neurodegenerative proteinopathies ENSG00000132341 PMC8716696__F4 Impact of Rubella Virus Infection on a Secondary Inflammatory Response in Polarized Human Macrophages ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000150455 PMC6110909__F1 Direct and indirect mechanisms of action of metformin in cancer cells ENSG00000175003 ENSG00000198793 PMC4547205__F2 Ingenuity pathway analysis comparing gingivitis to healthy subjects ENSG00000109819 ENSG00000176692 ENSG00000101255 ENSG00000106459 PMC8657018__F1 Promising Antigens for the New Frontier of Targeted Immunotherapy in Multiple Myeloma ENSG00000026751 ENSG00000168610 PMC9324879__F8 New EGFR Inhibitor from Ficus benghalensis Exerted Potential Anti-Inflammatory Activity via Akt/PI3K Pathway Inhibition ENSG00000146648 PMC3573709__F3 Protein-protein interaction network of NFY and associated genes ENSG00000136997 ENSG00000095002 PMC2637758__F5 Pathways and networks associated with HSPA9, PHB, and ABCB6 ENSG00000105329 ENSG00000054179 ENSG00000168610 ENSG00000139687 ENSG00000127616 PMC8996962__F2 Review of the Current Impact of Inhibitors of Apoptosis Proteins and Their Repression in Cancer ENSG00000102871 ENSG00000131323 ENSG00000127191 PMC11749133__F4 Immune responses by bufalin in cancer therapy ENSG00000167207 ENSG00000151012 ENSG00000110931 ENSG00000162924 PMC11749133__F3 Astragalus-mediated inhibition of tumor growth ENSG00000124882 ENSG00000168036 ENSG00000127528 ENSG00000026103 PMC11749133__F2 Impact of traditional Chinese herbal preparations on cancer pathways ENSG00000177606 ENSG00000172936 ENSG00000136869 PMC6966574__F4 Summary of deregulated genes within different glucose metabolism related pathways and the potential use of certain genes as independent predictors for OS and /or RFS ENSG00000148057 ENSG00000168679 ENSG00000180210 ENSG00000074800 ENSG00000143149 ENSG00000197444 ENSG00000197594 ENSG00000173599 ENSG00000100504 ENSG00000026103 ENSG00000109667 ENSG00000131473 ENSG00000171174 ENSG00000160883 ENSG00000067057 ENSG00000108515 ENSG00000100994 ENSG00000111713 ENSG00000147100 ENSG00000166816 ENSG00000023697 ENSG00000114268 ENSG00000124253 ENSG00000136872 ENSG00000168237 PMC7692959__F3 XIAP Signaling Pathways in Human Cancer ENSG00000087245 ENSG00000185591 ENSG00000146648 PMC5831762__F2 Simple diagrammatic representation of the (known) key events in Shh signaling at the primary cilium ENSG00000143147 ENSG00000180447 ENSG00000106571 ENSG00000144857 ENSG00000166813 ENSG00000164690 ENSG00000128602 PMC6895808__F1 Progression of thyroid cancer and the main genetic alterations involved in such process ENSG00000157764 ENSG00000164362 ENSG00000168036 ENSG00000132170 PMC6433817__F4 Some possible interactions between fungal cell regulatory hierarchies that could respond to oxidants and chemical stresses ENSG00000211445 ENSG00000123268 PMC7878386__F1 Leptin receptor isoforms and intracellular signaling ENSG00000169047 ENSG00000168610 PMC8285540__F7 Model depicting the role of FBXO32 in the crosstalk between CHOP-dependent apoptosis and autophagy ENSG00000005893 ENSG00000171791 ENSG00000164305 PMC6411369__F7 Molecular mechanism of miR-194-5p in HPC involves the mTOR signaling pathway by targeting SMURF1 ENSG00000198742 ENSG00000132646 ENSG00000198793 PMC7980524__F1 Structural and functional understanding of the toll‐like receptors ENSG00000174123 ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC4755870__F5 MicroRNA variants as genetic determinants of bone mass ENSG00000253293 ENSG00000134982 ENSG00000168036 ENSG00000104332 PMC8393865__F3 Concurrent BMP Signaling Maintenance and TGFB Signaling Inhibition Is a Hallmark of Natural Resistance to Muscle Atrophy in the Hibernating Bear ENSG00000135655 ENSG00000137834 ENSG00000103266 ENSG00000182670 ENSG00000120693 ENSG00000131263 ENSG00000116525 ENSG00000135341 ENSG00000076604 ENSG00000118496 ENSG00000123124 ENSG00000184979 ENSG00000170365 ENSG00000069869 ENSG00000181191 ENSG00000102226 ENSG00000118503 ENSG00000158022 ENSG00000078747 ENSG00000083799 ENSG00000175104 ENSG00000157450 PMC8393865__F2 Concurrent BMP Signaling Maintenance and TGFB Signaling Inhibition Is a Hallmark of Natural Resistance to Muscle Atrophy in the Hibernating Bear ENSG00000121989 ENSG00000111049 ENSG00000169071 ENSG00000157077 ENSG00000142178 ENSG00000108389 ENSG00000030304 ENSG00000101938 ENSG00000163083 ENSG00000197415 ENSG00000163132 ENSG00000171791 ENSG00000162772 ENSG00000118496 ENSG00000204262 ENSG00000141232 ENSG00000170365 ENSG00000157227 ENSG00000108821 ENSG00000164619 ENSG00000172201 ENSG00000158859 ENSG00000107779 ENSG00000087245 ENSG00000122180 ENSG00000108773 ENSG00000120693 ENSG00000135414 ENSG00000117152 ENSG00000130283 ENSG00000076604 ENSG00000136603 ENSG00000158022 ENSG00000112851 ENSG00000175104 ENSG00000096717 ENSG00000187955 ENSG00000157933 ENSG00000105329 ENSG00000139567 ENSG00000221914 ENSG00000010017 ENSG00000135966 ENSG00000111110 ENSG00000158747 ENSG00000135341 ENSG00000266524 ENSG00000137801 ENSG00000109819 ENSG00000039319 ENSG00000095739 ENSG00000128791 ENSG00000174136 ENSG00000111341 ENSG00000213999 ENSG00000189403 ENSG00000185591 ENSG00000283060 ENSG00000135503 ENSG00000125968 ENSG00000155090 ENSG00000100811 ENSG00000137834 ENSG00000023734 ENSG00000037965 ENSG00000183691 ENSG00000135253 ENSG00000113140 ENSG00000134363 ENSG00000174460 ENSG00000175826 ENSG00000081189 ENSG00000182175 ENSG00000162409 ENSG00000291748 ENSG00000156535 ENSG00000114166 ENSG00000204217 ENSG00000114739 PMC3074954__F1 ROS have different origins ENSG00000143799 ENSG00000132646 ENSG00000039650 ENSG00000137074 ENSG00000138385 PMC8623825__F1 Endothelial Dysfunction through Oxidatively Generated Epigenetic Mark in Respiratory Viral Infections ENSG00000079999 PMC8655846__F2 TypiCal but DeliCate Ca++re: Dissecting the Essence of Calcium Signaling Network as a Robust Response Coordinator of Versatile Abiotic and Biotic Stimuli in Plants ENSG00000105722 ENSG00000110395 ENSG00000099246 PMC8655846__F1 TypiCal but DeliCate Ca++re: Dissecting the Essence of Calcium Signaling Network as a Robust Response Coordinator of Versatile Abiotic and Biotic Stimuli in Plants ENSG00000110395 ENSG00000173599 PMC7037725__F1 Molecular mechanisms underlying GOLPH3 function in human cancer ENSG00000113384 ENSG00000174903 ENSG00000154217 ENSG00000198793 ENSG00000168036 ENSG00000168610 ENSG00000146648 PMC7673857__F1 Main source of ROS and redox reaction ENSG00000086991 PMC3317213__F4 Metabolism of xenobiotics by cytochrome P450 pathway, and ribosome map views of identified proteins ENSG00000090402 ENSG00000119912 ENSG00000167419 PMC9287557__F3 One carbon metabolism ENSG00000284320 ENSG00000228716 ENSG00000065911 ENSG00000144659 ENSG00000100714 ENSG00000164466 ENSG00000163738 ENSG00000120254 PMC4698510__F1 Molecular mechanisms of alcohol-related liver pathogenesis and therapeutic targets ENSG00000042832 ENSG00000130649 ENSG00000159346 ENSG00000096717 PMC8850794__F2 PI3K/Akt/mTOR pathway in lung cancer; oncogenic alterations, therapeutic opportunities, challenges, and a glance at the application of nanoparticles ENSG00000107562 ENSG00000170558 ENSG00000168036 ENSG00000169429 ENSG00000171791 ENSG00000121879 ENSG00000184481 ENSG00000164305 PMC9284214__F1 Insights on the cGAS-STING Signaling Pathway During Herpesvirus Infections ENSG00000105664 PMC8850794__F1 PI3K/Akt/mTOR pathway in lung cancer; oncogenic alterations, therapeutic opportunities, challenges, and a glance at the application of nanoparticles ENSG00000150907 ENSG00000198793 PMC4629436__F1 Representative HIF-1A regulatory genes and their effects on cancer progression ENSG00000115457 ENSG00000163235 ENSG00000148926 ENSG00000146678 ENSG00000159399 PMC9284214__F2 Insights on the cGAS-STING Signaling Pathway During Herpesvirus Infections ENSG00000183735 ENSG00000164430 ENSG00000100505 ENSG00000292211 ENSG00000175104 ENSG00000247315 ENSG00000276561 PMC5968093__F1 Antibodies that target leukemic stem cells (LSCs) and blasts directly ENSG00000139193 ENSG00000168036 ENSG00000154310 ENSG00000127191 PMC4629436__F3 Regulation of HIF-1A pathway at different levels ENSG00000134086 ENSG00000198793 PMC5094977__F7 Identification of myeloproliferative neoplasm drug agents via predictive simulation modeling: assessing responsiveness with micro-environment derived cytokines ENSG00000111537 ENSG00000171791 ENSG00000164305 ENSG00000139687 ENSG00000160691 PMC8576385__F3 Expression Profile and Potential Function of Circular RNAs in Peripheral Blood Mononuclear Cells in Male Patients With Primary Gout ENSG00000002330 ENSG00000172005 ENSG00000166278 PMC8371910__F2 Intestinal Regulatory T Cells as Specialized Tissue-Restricted Immune Cells in Intestinal Immune Homeostasis and Disease ENSG00000111537 ENSG00000137033 ENSG00000163599 PMC6189061__F5 Proposed model of irisin effects on pancreatic cancer ENSG00000198793 ENSG00000173599 PMC4594598__F2 RhoGEF signaling pathways involved in 3D migration ENSG00000168283 ENSG00000111859 ENSG00000070831 ENSG00000291971 ENSG00000198670 ENSG00000088538 ENSG00000135905 PMC10343815__F5 Differentially expressed genes in the cAMP metabolic pathway suggested that upregulated genes were dominant in this pathway ENSG00000104899 ENSG00000159224 ENSG00000002330 ENSG00000146469 ENSG00000157017 ENSG00000001626 ENSG00000157005 PMC5909795__F1 Regulation of the core components of the Hippo signaling pathway.Abbreviation: ER, estrogen receptor ENSG00000144560 ENSG00000163914 ENSG00000197905 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC8057882__F10 Acetylshikonin Induces Apoptosis in Human Colorectal Cancer HCT-15 and LoVo Cells via Nuclear Translocation of FOXO3 and ROS Level Elevation ENSG00000188486 PMC3371699__F4 miR-519d, miR-190, and miR-340 in the TGFB signaling pathway ENSG00000136457 ENSG00000183691 ENSG00000113558 ENSG00000136997 PMC4138699__F7 GAi-mediated activation of the PI3K-Akt-mTORC1 pathway in response to EGF ENSG00000138798 PMC2954312__F2 Crosstalk between the three distinct oscillators that function in the mouse PSM.(a) Schematic diagram of a signalling and a responding cell in the mouse PSM, detailing cyclic genes of the Notch, Fgf and Wnt pathways ENSG00000136158 ENSG00000154342 ENSG00000138795 ENSG00000198435 ENSG00000134982 ENSG00000120875 ENSG00000179111 ENSG00000168036 ENSG00000077782 ENSG00000168646 ENSG00000106003 ENSG00000140807 PMC5909795__F2 The Hippo pathway regulates organ metastases by controlling cell proliferation, EMT, and immune evasion.Abbreviation: EMT, epithelial–mesenchymal transition ENSG00000150457 ENSG00000131023 PMC7547073__F2 MicroRNA-34a targets the colorectal cancer pathway ENSG00000132906 ENSG00000138795 ENSG00000002330 ENSG00000177606 ENSG00000136997 ENSG00000168036 ENSG00000171791 ENSG00000169032 ENSG00000121879 ENSG00000168646 ENSG00000164305 PMC7962413__F2 Tick signaling-related genes in the three main immune signaling pathways of arthropods: (A) Toll, (B) IMD, and (C) JAK/STAT ENSG00000105298 ENSG00000130159 ENSG00000168040 PMC6160419__F5 Extracellular matrix organization pathway genes in COPD disease network module ENSG00000262406 ENSG00000137673 ENSG00000138640 ENSG00000133710 ENSG00000100448 ENSG00000138829 ENSG00000087303 ENSG00000166147 ENSG00000274542 ENSG00000277571 ENSG00000274247 ENSG00000117122 ENSG00000274334 ENSG00000100985 ENSG00000143196 ENSG00000163501 ENSG00000158859 PMC6066232__F1 Study of purinosome assembly in cell-based model systems with de novo purine synthesis and salvage pathway deficiencies ENSG00000128050 PMC7024605__F2 Metabolic Immunomodulation of Macrophage Functional Plasticity in Non-Healing Wounds ENSG00000125538 ENSG00000136869 PMC9264807__F2 SLC7A11 in Cancer: Friend or Foe? ENSG00000168003 ENSG00000198901 ENSG00000128272 ENSG00000151012 ENSG00000120686 ENSG00000169047 ENSG00000026508 ENSG00000120733 ENSG00000079999 PMC9264807__F1 SLC7A11 in Cancer: Friend or Foe? ENSG00000111537 ENSG00000151012 ENSG00000167468 ENSG00000115419 PMC6899468__F5 Schematic diagram showing the PST inhibition of gluconeogenesis in hepatocytes ENSG00000169047 ENSG00000149782 ENSG00000145321 ENSG00000166278 ENSG00000124253 PMC9147666__F2 Therapeutic Strategies for Ovarian Cancer in Point of HGF/c-MET Targeting ENSG00000019991 ENSG00000198793 ENSG00000168610 PMC6899468__F4 Schematic diagram showing the putative signaling pathways for the anti‐inflammatory actions of CST ENSG00000162711 ENSG00000102871 ENSG00000127191 PMC7880341__F5 NSCLC-pathway ENSG00000132906 ENSG00000226275 ENSG00000102871 PMC6899468__F2 Schematic diagram showing the inhibition of catecholamine secretion and regulation of cardiovascular functions by CST PMC11003275__F1 Schematic chart for molecular mechanisms of metabolic dysregulation in DCM ENSG00000157184 ENSG00000135218 ENSG00000026103 PMC2678244__F1 Abl Tyrosine Kinases in T-cell signaling ENSG00000291603 ENSG00000134982 ENSG00000113263 ENSG00000124181 ENSG00000141968 PMC9293612__F2 Crosstalk between tumor-associated macrophages and neighboring cells in hepatocellular carcinoma ENSG00000108691 ENSG00000107562 ENSG00000275718 ENSG00000198053 ENSG00000102970 ENSG00000272398 ENSG00000121807 ENSG00000168610 ENSG00000121966 ENSG00000115009 ENSG00000112486 PMC7583966__F3 Interferons after ligating to type II receptors activate JAK/STAT pathway resulting in foam cells formation leading directly to atherosclerosis development ENSG00000115415 ENSG00000162892 ENSG00000142224 PMC12229470__F6 Molecular mechanism by which AloAB suppresses HNSCC progression via inhibition of the STAT3/SLC7A11 signaling ENSG00000151012 ENSG00000170558 ENSG00000168610 ENSG00000167419 PMC10300995__F2 Altered amino acid metabolism and potential drugs in DLBCL ENSG00000136997 ENSG00000142082 ENSG00000115419 PMC9363460__F2 Key steps of the mevalonate (MVA) pathway leading to sterol and non-sterol isoprenoid synthesis ENSG00000131473 ENSG00000160752 ENSG00000130164 ENSG00000138135 ENSG00000113161 PMC10300995__F4 Influence of altered tumor metabolism on immune cells ENSG00000198829 ENSG00000118520 PMC9363460__F1 Non-exhaustive representation of lipid metabolic pathways addressed in the review ENSG00000157184 ENSG00000131473 ENSG00000135218 ENSG00000026103 PMC10300995__F3 Altered fatty acid metabolism and potential drugs in DLBCL ENSG00000131473 ENSG00000135218 ENSG00000198793 ENSG00000169710 PMC9363460__F3 Non-exhaustive scheme of lipid exchanges between tumor cells and tumor microenvironment (TME) cells and lipid reprogramming of stromal cells, that activate their pro-tumoral features ENSG00000135218 ENSG00000130164 ENSG00000113070 ENSG00000198670 ENSG00000160179 PMC6361534__F1 Complement cascade and its regulators ENSG00000039537 ENSG00000113600 ENSG00000236625 PMC6488628__F4 The cellular functions of the PLAC8 up-regulated genes ENSG00000158516 PMC7882000__F1 De novo synthesis and regulation of cholesterol ENSG00000116133 ENSG00000172893 ENSG00000167910 ENSG00000075239 PMC3544567__F2 Differentially expressed genes within the Wnt Signalling pathway ENSG00000134982 ENSG00000113558 PMC6361534__F3 Mechanisms through which complement modulates T cell-mediated rejection ENSG00000134830 ENSG00000134982 ENSG00000197405 ENSG00000049768 PMC12210318__F2 Complete RNM for the MAPK Cancer Cell Fate Network of Grieco et al ENSG00000136997 ENSG00000146648 PMC6070710__F11 Sepantronium Bromide (YM-155) on the Whole Transcriptome of MDA-MB-231 Cells: Highlight on Impaired ATR/ATM Fanconi Anemia DNA Damage Response ENSG00000110330 ENSG00000002330 ENSG00000282905 ENSG00000100906 ENSG00000109320 ENSG00000095015 ENSG00000173039 ENSG00000120889 ENSG00000213341 ENSG00000171791 ENSG00000168040 ENSG00000127191 ENSG00000215788 ENSG00000163141 ENSG00000177606 ENSG00000136997 ENSG00000056558 ENSG00000131323 ENSG00000120868 ENSG00000135116 ENSG00000026103 PMC7415428__F12 Schematically drawing the diagraph for illustrating the signaling pathway and pointing the action sites of melatonin ENSG00000102699 PMC6070710__F10 Sepantronium Bromide (YM-155) on the Whole Transcriptome of MDA-MB-231 Cells: Highlight on Impaired ATR/ATM Fanconi Anemia DNA Damage Response ENSG00000105329 ENSG00000134982 ENSG00000196591 ENSG00000184182 ENSG00000250254 ENSG00000112118 ENSG00000135476 ENSG00000073111 ENSG00000091651 ENSG00000145386 ENSG00000076003 ENSG00000118971 ENSG00000166851 ENSG00000134480 ENSG00000093009 ENSG00000175054 ENSG00000171720 ENSG00000112242 ENSG00000143761 ENSG00000115942 ENSG00000133740 ENSG00000253729 ENSG00000282899 ENSG00000117399 ENSG00000149311 ENSG00000145604 ENSG00000094804 ENSG00000065328 ENSG00000134057 ENSG00000156970 ENSG00000061273 ENSG00000132646 ENSG00000080839 ENSG00000175305 PMC2933206__F7 Hypothetical model of how Str1 may affect cellular behavior via the Beta-catenin/LEF signal transduction pathway ENSG00000134982 ENSG00000168036 PMC8794658__F8 Investigating the Molecular Mechanism of Xijiao Dihuang Decoction for the Treatment of SLE Based on Network Pharmacology and Molecular Docking Analysis ENSG00000142192 ENSG00000110514 ENSG00000150455 PMC1828075__F2 Diagram showing several factors involved in lens development ENSG00000138083 ENSG00000117707 PMC9182402__F5 Transcriptome Profiling of HCT-116 Colorectal Cancer Cells with RNA Sequencing Reveals Novel Targets for Polyphenol Nano Curcumin ENSG00000151725 ENSG00000277909 ENSG00000178999 ENSG00000092853 ENSG00000099860 ENSG00000182759 ENSG00000161888 ENSG00000162772 ENSG00000166851 ENSG00000186871 ENSG00000117724 ENSG00000122952 ENSG00000156970 ENSG00000177606 ENSG00000188404 ENSG00000130222 ENSG00000100479 ENSG00000282899 PMC7775424__F5 Hypothetical contribution of exRNA to virus infection and subsequent cardiovascular disease ENSG00000130234 PMC10888344__F9 Molecular mechanism that drives the positive impact of CSE in OVA-induced AR mouse model ENSG00000137033 ENSG00000197971 PMC8147868__F2 Epigenetics of Hepatic Insulin Resistance ENSG00000171105 ENSG00000171720 ENSG00000115457 ENSG00000150907 ENSG00000106070 ENSG00000169047 ENSG00000117707 ENSG00000096717 ENSG00000197724 PMC11314049__F5 Schematic illustration of reactive oxygen species (ROS)-mediated activation of various cell signaling pathways in the skin ENSG00000171791 PMC7801517__F7 ABCA8-mediated efflux of taurocholic acid contributes to gemcitabine insensitivity in human pancreatic cancer via the S1PR2-ERK pathway ENSG00000171791 ENSG00000267534 ENSG00000164949 PMC7716140__F1 Figure shows the pharmacological effects of ulinastatin ENSG00000172936 ENSG00000136869 PMC7732991__F7 OXER1 and RACK1-associated pathway: a promising drug target for breast cancer progression ENSG00000162881 PMC5759779__F3 Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer's disease ENSG00000129219 PMC4652780__F6 Network overview of the biomarkers in lung cancer and ALL ENSG00000111605 ENSG00000135218 ENSG00000007312 ENSG00000127022 ENSG00000139890 ENSG00000171791 ENSG00000120800 ENSG00000164751 ENSG00000129351 ENSG00000157212 ENSG00000292210 ENSG00000181090 ENSG00000107263 ENSG00000115850 ENSG00000038427 ENSG00000177084 PMC8278085__F7 PU.1 inhibition attenuates atrial fibrosis and atrial fibrillation vulnerability induced by angiotensin‐II by reducing TGF‐B1/Smads pathway activation ENSG00000162733 PMC5348352__F5 miR-22 targets YWHAZ to inhibit metastasis of hepatocellular carcinoma and its down-regulation predicts a poor survival ENSG00000170558 ENSG00000100985 PMC7461028__F6 PI3K-Akt signaling pathway is downregulated in U87 glioblastoma cells overexpressing ZNF554 ENSG00000112576 ENSG00000171105 ENSG00000002330 ENSG00000105401 ENSG00000198793 ENSG00000169047 ENSG00000101680 ENSG00000137801 ENSG00000078304 ENSG00000177455 ENSG00000145431 ENSG00000012048 ENSG00000175634 ENSG00000185652 ENSG00000103479 ENSG00000053747 ENSG00000145623 ENSG00000186716 ENSG00000066027 ENSG00000136997 ENSG00000154188 ENSG00000175305 PMC3875894__F3 mTOR signaling pathway (#hsa04150) ENSG00000157764 ENSG00000078399 ENSG00000198793 ENSG00000164327 PMC4219921__F1 Steroid hormone synthesis pathways in the adrenal gland and testis ENSG00000203859 ENSG00000179142 PMC3875894__F1 Pathway Protection Loop ENSG00000164327 PMC9456549__F2 Targeting PI3K/AKT/mTOR Signaling Pathway in Pancreatic Cancer: From Molecular to Clinical Aspects ENSG00000198793 PMC4061877__F4 Hypothetical outcomes for demyelinated axon.Denuded axon impermissive for myelination ENSG00000169783 ENSG00000237834 PMC3509687__F1 Impact of the cellular restriction factor APOBEC3 (A3) on human immunodeficiency virus-1 (HIV-1) replication ENSG00000149311 ENSG00000175054 ENSG00000131015 PMC3875894__F4 Antigen processing and presentation (APP) pathway (#hsa04612) ENSG00000111537 ENSG00000127022 ENSG00000273686 ENSG00000231925 PMC4219921__F2 Classical and non-classical pathways of androgen biosynthesis ENSG00000135437 ENSG00000086696 ENSG00000151632 ENSG00000197888 ENSG00000196620 ENSG00000203857 ENSG00000187134 PMC4040584__F1 Expansion of the SDF-1/CXCR4 migratory signaling network in breast cancer stem cells ENSG00000163629 ENSG00000250506 ENSG00000277273 ENSG00000121966 ENSG00000198586 PMC3894712__F4 Autophagy in Kidney Health and Disease ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC5601256__F3 Natural killer (NK) cell activating receptor signaling ENSG00000291603 ENSG00000101146 ENSG00000010810 ENSG00000141968 PMC9453876__F14 Honokiol improves depression-like behaviors in rats by HIF-1Alpha- VEGF signaling pathway activation ENSG00000198793 PMC9027058__F2 KRAS: A Druggable Target in Colon Cancer Patients ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC9477010__F3 Pyroptosis and its crosstalk with immune therapy in breast cancer ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000168610 ENSG00000147697 ENSG00000149295 PMC9477010__F1 Pyroptosis and its crosstalk with immune therapy in breast cancer ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000091592 ENSG00000145649 ENSG00000189403 ENSG00000147697 ENSG00000073605 PMC6614129__F3 Ceramide and Sphingosine-1-Phosphate in Alzheimer’s Disease and Other Neurodegenerative Disorders ENSG00000002330 ENSG00000196591 ENSG00000127191 PMC8299191__F6 Map of dimorphic switching-related signaling pathways in Sporothrix schenckii based on its transcriptome ENSG00000017797 ENSG00000070831 ENSG00000136425 PMC8350388__F1 Role of Traditional Chinese Medicines by Wnt/Beta-Catenin Pathway Compared With Targeted Small Molecules in Colorectal Cancer Therapy ENSG00000166167 ENSG00000134982 ENSG00000138798 ENSG00000168036 ENSG00000108375 ENSG00000146648 PMC5717492__F8 EMT signaling induced during P ENSG00000087245 ENSG00000168036 PMC2852600__F2 CD40 responsiveness in Leishmania-infected macrophages: crosslinking of anti-CD40 antibody activates p38 MAPK-induced leishmanicidal function via iNOS2 induction ENSG00000115415 PMC4556375__F5 Dysregulated Hepatic Methionine Metabolism Drives Homocysteine Elevation in Diet-Induced Nonalcoholic Fatty Liver Disease ENSG00000173599 ENSG00000113161 ENSG00000126457 PMC7656798__F1 PI3K/AKT/mTOR signaling pathway in cancer ENSG00000198793 PMC3184251__F1 Smac mimetics and TNFA: a dangerous liaison? ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC5412537__F1 Diagram of IL-10 and IL-10R pathway ENSG00000105397 ENSG00000168610 PMC5362499__F4 LncSubpathway: a novel approach for identifying dysfunctional subpathways associated with risk lncRNAs by integrating lncRNA and mRNA expression profiles and pathway topologies ENSG00000112378 PMC8616345__F2 Advances in Immunotherapy and the TGFB Resistance Pathway in Metastatic Bladder Cancer PMC8255536__F4 Proposed mechanism on cartilage repair and chondroprotective effects of IGF1-induced SMMSC-CM therapy ENSG00000125398 ENSG00000156427 ENSG00000158859 PMC4099360__F1 Toll-like receptor 4 and hepatic fibrogenesis ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC8900732__F1 The Cannabinoid System in the Basal Ganglia in Parkinson’s Disease ENSG00000196689 PMC5426649__F8 Hypothetical model for IGF-I regulation of kitlga expression and its signaling mechanisms in the zebrafish follicle cells ENSG00000138798 ENSG00000146648 PMC8616345__F4 Advances in Immunotherapy and the TGFB Resistance Pathway in Metastatic Bladder Cancer PMC9271914__F1 Gut Microbiota-Bile Acids Axis in the Progression of Non-alcoholic Fatty Liver Disease ENSG00000160867 ENSG00000167910 ENSG00000135929 PMC5083749__F1 Upstream and downstream signaling in the mTOR pathway ENSG00000149311 ENSG00000162009 ENSG00000134086 ENSG00000157764 ENSG00000198793 ENSG00000170430 ENSG00000146648 ENSG00000140443 PMC11054859__F6 KEGG pathway (hsa05226 gastric cancer) ENSG00000134982 ENSG00000164690 ENSG00000293532 ENSG00000122008 PMC11054859__F5 KEGG pathway (hsa05200 pathway in cancer) ENSG00000111837 ENSG00000168040 ENSG00000282891 PMC5267446__F3 Acute myeloid leukemia and oncogenic Hedgehog/GLI signaling ENSG00000122025 ENSG00000141867 ENSG00000157540 ENSG00000198793 ENSG00000128602 ENSG00000105204 PMC12191077__F1 Proton-sensing GPCR-related signaling pathway ENSG00000163914 ENSG00000177464 ENSG00000183484 PMC7602033__F2 Cardiac remodeling by microRNAs and the functions of their target mRNAs ENSG00000168610 PMC11054859__F7 KEGG pathway (hsa04151 P13K-AKT signaling pathway) ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000127948 PMC3276472__F1 Schematic in vivo biosynthetic pathway from 18:3n3 and 18:2n6 mediated by ELOVL4 and other ELOVL family proteins ENSG00000118402 ENSG00000119915 ENSG00000066322 ENSG00000197977 PMC2783774__F4 miRNA process pathway ENSG00000090905 ENSG00000139546 ENSG00000100697 ENSG00000128191 ENSG00000132341 PMC3092604__F1 General scheme of the SBP in Tritryps ENSG00000154227 ENSG00000173599 ENSG00000119537 ENSG00000102172 PMC4981705__F1 PI3K/Akt/mTOR signaling pathway and the existing molecular targets for therapy, which was indicated by ∆ ENSG00000101407 ENSG00000169047 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC3092604__F2 Lipid remodeling pathways in mammals, yeast and T ENSG00000161395 ENSG00000109182 ENSG00000109743 ENSG00000148985 ENSG00000179094 PMC11056518__F3 IL-23 and IL-12 and their receptors, with summary of associated effector cells, cytokines, and immune function ENSG00000162594 ENSG00000138378 ENSG00000105397 ENSG00000168610 PMC9138510__F1 TGFB as a Key Modulator of Astrocyte Reactivity: Disease Relevance and Therapeutic Implications PMC4755014__F5 KEGG pathway map (cin04310) of the WNT Signaling Pathway with DE genes indicated ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000132478 ENSG00000196470 ENSG00000164736 ENSG00000100592 ENSG00000095739 ENSG00000100387 ENSG00000147869 ENSG00000167941 ENSG00000113558 PMC5368692__F2 MYC-dependent metabolic reprograming in immunity As schematically shown here, MYC regulates immune cell metabolic reprogramming in different contexts ENSG00000186716 ENSG00000136997 ENSG00000116990 PMC4175497__F1 Molecular signaling altered in Fragile X syndrome ENSG00000142192 ENSG00000198576 ENSG00000087085 ENSG00000100985 PMC8048291__F9 Schematic depiction of endolysosomal pathway dysregulation in Huntington’s disease ENSG00000197386 ENSG00000135404 PMC11655665__F0 Epoxy metabolites of linoleic acid promote the development of breast cancer via orchestrating PLEC/NFKB1/CXCL9-mediated tumor growth and metastasis ENSG00000109320 ENSG00000138755 ENSG00000178209 ENSG00000134716 PMC12041774__F6 Effect of TCM monomers, formulations and small-molecule inhibitors on the Wnt/Beta-catenin signaling pathway ENSG00000087095 ENSG00000138795 ENSG00000116729 ENSG00000136997 ENSG00000168036 ENSG00000083799 PMC12041774__F1 Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC12041774__F3 Effect of angiogenesis in CRC ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8318642__F3 Possible effects of chemokine-like factor-like MARVEL transmembrane domain-containing family on antiphospholipid syndrome ENSG00000095585 ENSG00000140931 ENSG00000089505 ENSG00000091317 ENSG00000186716 ENSG00000125538 ENSG00000153551 ENSG00000140932 PMC11693507__F2 IL-6 signaling pathway in kidney cells ENSG00000167601 ENSG00000168610 PMC9606688__F2 mTORC1 beyond anabolic metabolism: Regulation of cell death ENSG00000177169 ENSG00000186575 ENSG00000151012 ENSG00000150457 ENSG00000023909 ENSG00000131023 ENSG00000285069 ENSG00000079999 PMC8529048__F2 Anti-flavivirus Properties of Lipid-Lowering Drugs ENSG00000172893 ENSG00000113161 ENSG00000167508 ENSG00000026103 PMC5811610__F6 Sialylation pathway in eukaryotes ENSG00000170191 ENSG00000138459 ENSG00000124568 ENSG00000111726 ENSG00000164414 ENSG00000176087 ENSG00000101194 ENSG00000095380 PMC12234022__F3 Chemically modified ncRNAs in diseases ENSG00000145388 ENSG00000037897 ENSG00000130826 ENSG00000160193 ENSG00000047188 ENSG00000037474 ENSG00000275272 ENSG00000055044 ENSG00000111641 PMC9393728__F8 EST12 regulates Myc expression and enhances anti-mycobacterial inflammatory response via RACK1-JNK-AP1-Myc immune pathway ENSG00000136997 PMC5270476__F1 Reelin's role in stabilizing the cytoskeleton ENSG00000106683 ENSG00000070831 ENSG00000198793 ENSG00000173406 PMC4453536__F8 Regulation pathway from HBV infection to complement activation ENSG00000125538 ENSG00000134070 ENSG00000196352 ENSG00000117335 ENSG00000000971 ENSG00000175104 PMC12192919__F2 Myostatin-mediated muscle atrophy in SMA PMC8146031__F2 Improving Gemcitabine Sensitivity in Pancreatic Cancer Cells by Restoring miRNA-217 Levels ENSG00000136997 ENSG00000172005 PMC4875670__F2 Network of gene interaction NF-KB pathway obtained from the subtraction of the control Hep-2 cells ENSG00000197372 ENSG00000197622 ENSG00000135960 PMC8146031__F8 Improving Gemcitabine Sensitivity in Pancreatic Cancer Cells by Restoring miRNA-217 Levels ENSG00000175054 ENSG00000078900 ENSG00000109321 ENSG00000095303 ENSG00000272398 ENSG00000277263 ENSG00000204520 ENSG00000121966 PMC3073487__F4 Functions of 14-3-3 in tumor-suppressor pathways ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC10310986__F5 Histone post-translational modification and the DNA damage response ENSG00000012048 ENSG00000187531 ENSG00000171720 ENSG00000166436 ENSG00000096717 PMC8990993__F5 Immunomodulatory Effect and an Intervention of TNF Signalling Leading to Apoptotic and Cell Cycle Arrest on ORL-204 Oral Cancer Cells by Tiger Milk Mushroom, Lignosus rhinocerus ENSG00000102871 ENSG00000168040 PMC6275466__F3 NOTCH signaling in B cell development ENSG00000148400 PMC6749531__F7 Active constituent-protein targets-signaling pathway network of frankincense–myrrh compound against breast cancer ENSG00000175054 ENSG00000083093 ENSG00000104320 ENSG00000198793 ENSG00000108384 ENSG00000168036 ENSG00000073756 ENSG00000095002 ENSG00000196396 ENSG00000139618 PMC7843420__F8 STAT3 phosphorylation at Ser727 and Tyr705 differentially regulates the EMT–MET switch and cancer metastasis ENSG00000178860 ENSG00000122691 ENSG00000107485 ENSG00000128342 ENSG00000112149 ENSG00000168610 PMC6275466__F2 NOTCH signaling pathway ENSG00000140564 ENSG00000133961 ENSG00000132964 PMC8609314__F6 Activation of PTH1R alleviates epididymitis and orchitis through Gq and Beta-arrestin-1 pathways ENSG00000169245 PMC8623313__F1 Kinase-Inhibitors in Iodine-Refractory Differentiated Thyroid Cancer—Focus on Occurrence, Mechanisms, and Management of Treatment-Related Hypertension ENSG00000198793 PMC5138252__F4 Examples of genes (in red) within the HIF pathway in which positive selection has been identified in high-altitude populations ENSG00000269858 ENSG00000007171 PMC6952783__F1 Mesenchymal Stem Cell-Derived Exosomes and Other Extracellular Vesicles as New Remedies in the Therapy of Inflammatory Diseases ENSG00000102970 ENSG00000175104 ENSG00000106178 PMC3870610__F8 Signaling pathway of the AMH protein ENSG00000104899 ENSG00000170365 ENSG00000135409 PMC8263891__F6 Therapeutic targets and biological mechanisms of Centella asiatica on hepatic fibrosis: a study of network pharmacology ENSG00000142192 ENSG00000133105 ENSG00000173039 ENSG00000248099 PMC8263891__F5 Therapeutic targets and biological mechanisms of Centella asiatica on hepatic fibrosis: a study of network pharmacology ENSG00000087095 ENSG00000170458 ENSG00000115718 ENSG00000127191 ENSG00000081189 ENSG00000026103 PMC5297752__F1 Unfolded protein response (UPR) pathways in mammalian cells ENSG00000128272 ENSG00000127191 PMC10605634__F1 Tumor intrinsic factors related to immune evasion and ICI resistance ENSG00000089692 ENSG00000224320 ENSG00000134982 ENSG00000168036 ENSG00000273686 ENSG00000125347 PMC6408937__F1 T cell activation induces cell surface expression of GLUT1 and amino acid transporters, facilitating uptake of glucose and glutamine ENSG00000147162 ENSG00000198408 PMC9241034__F6 Interplay between H3K36me3, methyltransferase SETD2, and mismatch recognition protein MutSA facilitates processing of oxidative DNA damage in human cells ENSG00000149311 ENSG00000181555 PMC12204016__S1 Expression of exosome miR-30a-3p was up-regulated in the lead (Pb)-exposed group, suggesting that the abnormal expression of exosome miR-30a-3p derived from osteoclasts may be involved in the Pb-exposed group ENSG00000278718 ENSG00000269335 PMC9427794__F7 Schematic model of GASP1 promoting malignant phenotypes of breast cancer cells and decreasing their response to paclitaxel by forming a positive feedback loop with the IGF1/IGF1R pathway ENSG00000140443 PMC2536824__F4 Ingenuity Pathway Analysis (IPA) of genes specifically overexpressed in B1-Arg389 transgenic mouse hearts ENSG00000116001 ENSG00000136603 ENSG00000151617 PMC12176239__F1 RA signaling pathway regulates the dynamic balance of differentiation and proliferation in LECs ENSG00000095596 ENSG00000121207 ENSG00000114115 PMC10380640__F4 Crosstalk of Inflammation and Coagulation in Bothrops Snakebite Envenoming: Endogenous Signaling Pathways and Pathophysiology ENSG00000009724 ENSG00000113600 ENSG00000291559 ENSG00000244731 ENSG00000166278 PMC8971670__F5 Targeting Oncoproteins for Degradation by Small Molecule-Based Proteolysis-Targeting Chimeras (PROTACs) in Sex Hormone-Dependent Cancers ENSG00000184012 PMC12174920__F4 Molecular mechanism of KGN induced Hippo/TAOK1 Signalling Pathway ENSG00000114978 PMC6715949__F1 Mucosal innate immune responses to STIs in the female genital tract that could potentiate HIV transmission risk ENSG00000125538 ENSG00000172936 ENSG00000276561 PMC9085972__F11 BAG3 regulation of Rab35 mediates the Endosomal Sorting Complexes Required for Transport /endolysosome pathway and tau clearance ENSG00000169221 ENSG00000151929 ENSG00000111737 PMC6898841__F5 The schematic presentation for the signaling of the top 3 kinases crucial for cardiomyocyte survival ENSG00000198793 ENSG00000140443 PMC8584457__F1 Targeting Inflammatory Signaling in Prostate Cancer Castration Resistance ENSG00000120910 ENSG00000104856 PMC7551521__F1 Immune responses induced by SARS-CoV-2 ENSG00000183735 ENSG00000088888 PMC5416822__F3 Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases ENSG00000162711 ENSG00000124256 ENSG00000213928 ENSG00000163568 ENSG00000168040 ENSG00000142166 ENSG00000154451 ENSG00000164430 ENSG00000088888 ENSG00000115415 ENSG00000136869 ENSG00000172936 ENSG00000064012 ENSG00000285379 PMC4552438__F8 Paracrine networks acting downstream of epithelial ESR1 in the mouse uterus during implantation ENSG00000082175 ENSG00000113070 ENSG00000128342 ENSG00000163501 ENSG00000146648 PMC8102595__F1 Effect of plane of nutrition in early life on the transcriptome of visceral adipose tissue in Angus heifer calves ENSG00000178860 ENSG00000168000 ENSG00000122877 ENSG00000168036 ENSG00000175029 ENSG00000109787 ENSG00000283100 ENSG00000245848 ENSG00000163904 ENSG00000170365 ENSG00000176692 ENSG00000143379 ENSG00000134324 ENSG00000114115 ENSG00000109670 PMC9395612__F2 Research progress on exosomes/microRNAs in the treatment of diabetic retinopathy ENSG00000102871 ENSG00000101134 ENSG00000127191 PMC5132409__F3 Retinoid transformations and enzymes of the classical and intraretinal visual cycles ENSG00000135437 ENSG00000121207 ENSG00000116745 ENSG00000197713 ENSG00000080511 PMC6907741__F3 Regulatory Mechanisms of B7x Expression ENSG00000173039 ENSG00000168610 PMC3309773__F1 Regulation of ISGs by Akt1 and EMSY ENSG00000213928 ENSG00000187608 ENSG00000158636 ENSG00000115415 ENSG00000185885 PMC7291868__F4 Common neuroinflammatory pathways in different neurological diseases regulated by miR-146a ENSG00000000971 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC6917592__F1 Induction and subversion of the innate IFN response by HCMV ENSG00000124256 ENSG00000213928 ENSG00000187608 ENSG00000185745 ENSG00000185885 ENSG00000168610 ENSG00000183735 ENSG00000239732 ENSG00000111537 ENSG00000164430 ENSG00000088888 ENSG00000185201 ENSG00000172936 ENSG00000142089 PMC8507163__F5 Identification of common microRNA between COPD and non-small cell lung cancer through pathway enrichment analysis ENSG00000002330 ENSG00000100842 ENSG00000073111 ENSG00000164162 ENSG00000121879 ENSG00000164305 ENSG00000069667 ENSG00000175054 ENSG00000112242 ENSG00000143320 ENSG00000113558 ENSG00000136997 ENSG00000166501 ENSG00000115942 ENSG00000197386 ENSG00000112742 ENSG00000139687 ENSG00000282899 ENSG00000134438 ENSG00000157764 ENSG00000149311 ENSG00000189283 ENSG00000145604 ENSG00000117020 ENSG00000004897 ENSG00000112378 ENSG00000171608 ENSG00000146648 ENSG00000127948 ENSG00000143924 ENSG00000122008 PMC2704251__F1 Porphyromonas gingivalis-Host Interactions: Open War or Intelligent Guerilla Tactics? ENSG00000174125 ENSG00000172936 ENSG00000150455 ENSG00000121966 PMC2765277__F5 Amino acid producing elementary flux patterns ENSG00000122966 ENSG00000101440 ENSG00000172005 ENSG00000115419 PMC4309737__F4 PTEN-PI3K-AKT pathway in oocytes regulates primordial follicle activation ENSG00000157404 ENSG00000138798 PMC2765277__F3 Scheme of part of the central metabolism of E ENSG00000122966 ENSG00000172005 PMC4309737__F3 Actin polymerization disrupts ovarian Hippo signaling and promotes nuclear YAP actions to increase downstream CCN growth factors and apoptosis inhibitors involvement in POI, PCOS, follicle reserve, and infertility ENSG00000147202 ENSG00000197905 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC11033207__F6 Redox signaling and skeletal muscle adaptation during aerobic exercise ENSG00000104856 ENSG00000178573 ENSG00000102871 ENSG00000167468 ENSG00000173039 ENSG00000111321 ENSG00000087250 ENSG00000168040 ENSG00000096717 ENSG00000142082 ENSG00000089163 PMC6709869__F2 Signaling Pathways Regulating Hematopoietic Stem Cell and Progenitor Aging ENSG00000178860 ENSG00000107562 ENSG00000070831 ENSG00000198793 ENSG00000171791 ENSG00000096717 ENSG00000127666 PMC11033207__F1 Redox signaling and skeletal muscle adaptation during aerobic exercise ENSG00000086991 ENSG00000103375 PMC6882982__F6 Most significant module of PPI network of DEPs involved in ECM-receptor interaction, focal adhesion, and PI3K-Akt signaling pathway ENSG00000058085 ENSG00000130702 ENSG00000169031 ENSG00000197565 ENSG00000091409 ENSG00000081052 ENSG00000101680 ENSG00000172037 ENSG00000139219 ENSG00000053747 ENSG00000213949 ENSG00000188157 ENSG00000291748 PMC6882982__F5 PI3K-Akt signaling pathway changed in FSH-positive relative to negative NFPAs ENSG00000177455 ENSG00000124102 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000197601 PMC3776022__F1 GABAA receptor subunit regulation after status epilepticus (SE) ENSG00000168610 PMC3309773__F7 The functional role of Akt1, EMSY, and BRCA2 in the regulation of ISGs ENSG00000213928 ENSG00000105397 ENSG00000158636 ENSG00000142166 ENSG00000139618 PMC12174920__F8 Molecular mechanism of KGN induced JNK/RUNX-1 signalling pathway ENSG00000125398 ENSG00000159216 ENSG00000168036 PMC12174920__F7 Molecular mechanism of KGN induced AMPK-SIRT1/Antioxidant signalling pathway ENSG00000170365 ENSG00000125398 ENSG00000120693 ENSG00000096717 PMC12174920__F6 Molecular representation of repressed (left), in absence of hh ligands and activated (right) KGN induced hh signalling pathway, in presence of hh ligands ENSG00000106571 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC8182896__F2 Ang/Tie signalling pathway under physiological and pathophysiological conditions ENSG00000116001 ENSG00000140575 ENSG00000150907 ENSG00000112715 ENSG00000162692 PMC7921686__F8 Integrated pathways map of fucosterol in the treatment of NSCLC include (A) the non-small cell lung cancer pathway, marked in yellow as the functional targets of fucosterol, and (B) the key signal transduction pathways ENSG00000132906 ENSG00000189283 ENSG00000002330 PMC7921686__F7 Target-pathway network, constructed in Cytoscape3.7.2 (https://cytoscape.org/), was built by the candidate targets and a pathway if the pathway was lighted at the target ENSG00000087245 ENSG00000157404 ENSG00000082175 ENSG00000149968 ENSG00000128052 ENSG00000123374 ENSG00000105639 ENSG00000164305 ENSG00000178568 ENSG00000179295 PMC6138560__F2 Immunobiology of Ubiquitin-Dependent B Cell Receptor Functions ENSG00000110395 ENSG00000078747 PMC7917218__F1 The Unfolded Protein Response (UPR) is regulated by three transmembrane endoplasmic reticulum (ER) receptors: PERK, ATF6 and IRE1A ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC9298971__F1 Overnutrition Induced Cognitive Impairment: Insulin Resistance, Gut-Brain Axis, and Neuroinflammation ENSG00000115138 PMC7603112__F1 Vitamin D metabolic pathway by cytochrome P450 oxidases (CYPs) ENSG00000111012 ENSG00000019186 ENSG00000186104 ENSG00000135929 PMC3931394__F2 Transcriptomic analysis of isolated islets from GLU+IL–infused 6-month-old rats ENSG00000113070 ENSG00000175567 ENSG00000166851 PMC3438361__F2 Illustration of the metabolic pathway analysis for zidovudine with thick arrows indicating targets identified by the automatic classifier ENSG00000137204 ENSG00000124479 ENSG00000197901 ENSG00000171234 ENSG00000130649 ENSG00000168065 ENSG00000145020 ENSG00000197506 PMC7519869__F7 Diagram presentation of the molecular mechanism ENSG00000168036 PMC5794005__F1 Denosumab: Targeting the RANKL pathway to treat Rheumatoid Arthritis ENSG00000170909 ENSG00000111537 ENSG00000131323 ENSG00000175104 ENSG00000131196 PMC6931156__F2 Frontotemporal Dementia/Amyotrophic Lateral Sclerosis (FTD/ALS) and Parkinson’s disease (PD)-Associated Genes Converge on the Lysosome ENSG00000183735 ENSG00000273607 ENSG00000132718 ENSG00000030582 ENSG00000123240 ENSG00000106460 ENSG00000089063 ENSG00000158828 ENSG00000106153 ENSG00000127419 ENSG00000108518 ENSG00000147894 PMC6931156__F3 Rab Proteins Have Convergent Roles in Frontotemporal Dementia/Amyotrophic Lateral Sclerosis (FTD/ALS) and Parkinson’s disease (PD) ENSG00000183735 ENSG00000155961 ENSG00000089063 ENSG00000084733 ENSG00000111737 ENSG00000147894 PMC11694147__F7 Mechanism of protective effect of Herpetospermum pedunculosum seeds on liver ENSG00000079999 PMC3321808__F4 Differential regulation of genes in the IL-10 pathway in neonates and school-age children with septic shock versus age-matched controls ENSG00000105397 ENSG00000185591 ENSG00000175104 ENSG00000168610 PMC2168724__F1 Coenzyme B12 biosynthesis in serovar Typhimurium ENSG00000142192 ENSG00000124479 PMC3321808__F5 Differential regulation of genes in the antigen presentation pathway in neonates and school-age children with septic shock versus age-matched controls ENSG00000111537 ENSG00000163631 PMC9233348__F1 Cytokines and microRNAs in SARS-CoV-2: What do we know? ENSG00000130234 PMC3693579__F5 Signal transduction in MMTV-Pax8PPARG mice ENSG00000272398 ENSG00000168036 PMC3562414__F2A Surfactant phospholipid metabolism ENSG00000173599 ENSG00000184207 ENSG00000133027 PMC5061430__F6 Role of the Tomato Non-Ripening Mutation in Regulating Fruit Quality Elucidated Using iTRAQ Protein Profile Analysis ENSG00000105722 ENSG00000074266 ENSG00000198125 ENSG00000084774 PMC8926997__F7 Mechanism and Function of miRNA in Intervertebral Disc Degeneration ENSG00000158290 ENSG00000139842 PMC7768255__F3 Starvation Responses Throughout the Caenorhabditis elegans Life Cycle PMC5787446__F4 Drug resistance related to aberrant glycosylation in colorectal cancer ENSG00000026508 ENSG00000146648 PMC5787446__F3 Drug resistance related to aberrant glycosylation in colorectal cancer ENSG00000012061 ENSG00000172831 ENSG00000104884 ENSG00000173638 ENSG00000123191 ENSG00000103222 ENSG00000166278 ENSG00000112759 ENSG00000118777 ENSG00000121270 ENSG00000023839 ENSG00000262243 PMC6379582__F6 Model hypothesizing the potential regulation of Beta-catenin by G-alpha subunits and PMT ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC9106457__F5 Exosomes in Chronic Liver Disease Development and Their Potential Clinical Applications PMC4655987__F1 Aerobic very long chain-PUFA biosynthetic pathways modified from Napier () including microorganisms, plants, and animals PMC9414791__F12 Walnut Prevents Cognitive Impairment by Regulating the Synaptic and Mitochondrial Dysfunction via JNK Signaling and Apoptosis Pathway in High-Fat Diet-Induced C57BL/6 Mice ENSG00000145321 ENSG00000119912 PMC4960658__F2 p120 catenin: an essential regulator of cadherin stability, adhesion-induced signaling, and cancer progression ENSG00000291971 ENSG00000146648 PMC9588904__F5 Transcriptomics-based network medicine approach identifies metformin as a repurposable drug for atrial fibrillation ENSG00000142192 ENSG00000065911 ENSG00000169896 ENSG00000198793 ENSG00000135413 ENSG00000081052 ENSG00000265972 ENSG00000188175 ENSG00000115970 ENSG00000115718 ENSG00000166147 ENSG00000135324 ENSG00000149311 ENSG00000077009 ENSG00000135457 ENSG00000150991 ENSG00000177138 ENSG00000067248 ENSG00000205277 ENSG00000136997 ENSG00000124357 ENSG00000175899 ENSG00000148154 PMC5935233__F3 Oncogene-induced genomic instability ENSG00000012048 ENSG00000083093 ENSG00000160957 ENSG00000165392 ENSG00000197299 ENSG00000139618 PMC7410499__F1 Functionally annotated network of genes involved in the hypertension-hypotension axis whose expression across the GTEx population is correlated and anticorrelated with the AGTR1 and AGTR2 receptors ENSG00000064601 PMC5867859__F2 Wnt signalling in the adult Drosophila midgut during homeostasis, regeneration, ageing and hyperplasia ENSG00000134982 ENSG00000140287 ENSG00000146648 ENSG00000173273 PMC9099915__F2 Towards Understanding the Gene-Specific Roles of GATA Factors in Heart Development: Does GATA4 Lead the Way? ENSG00000285109 ENSG00000089225 PMC3917548__F1 The interleukin (IL)-21 receptor signaling pathway ENSG00000169291 ENSG00000103522 ENSG00000105639 ENSG00000168610 PMC3950548__F2 Representation of IL-33 pathway in T-helper cells ENSG00000137033 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC2759052__F1 Signal transduction pathway mediated by epidermal growth factor receptor (EGFR) ENSG00000198793 ENSG00000146648 PMC7047088__F3 HIF-mediated gene expression in metabolic reprogramming ENSG00000074800 ENSG00000114268 ENSG00000196365 ENSG00000159399 PMC4155324__F4 Transcription factor-pathway co-expression analysis reveals cooperation between SP1 and ESR1 on dysregulating cell cycle arrest in non-hyperdiploid multiple myeloma ENSG00000185591 PMC5722633__F4 Mass spectrometry-based proteomic analysis of Homer2-interacting proteins in the mouse brain ENSG00000161681 ENSG00000175866 ENSG00000197283 ENSG00000033122 ENSG00000162105 ENSG00000051128 ENSG00000277363 ENSG00000292254 ENSG00000103942 ENSG00000107959 PMC11077374__F3 HuR during Wnt/Beta-catenin signaling pathway, autophagy and drug resistance in pancreatic cancer ENSG00000106263 ENSG00000168036 ENSG00000146457 PMC7511812__F7 Major molecular pathways ENSG00000136807 ENSG00000125538 PMC11077374__F1 LncRNAs in modulating the Wnt/Beta-catenin signaling pathway in pancreatic cancer ENSG00000136891 ENSG00000164713 ENSG00000156076 ENSG00000281324 ENSG00000134982 ENSG00000078399 ENSG00000150907 ENSG00000131747 ENSG00000106263 ENSG00000168036 ENSG00000146457 ENSG00000196363 PMC11077374__F7 HIF in regulating Wnt/Beta-catenin signaling pathway and autophagy in pancreatic cancer ENSG00000132964 ENSG00000269858 ENSG00000196628 ENSG00000062716 PMC11077374__F5 FOXM1 in regulating Wnt/Beta-catenin signaling pathway and autophagy in pancreatic cancer ENSG00000168036 PMC11077374__F4 FOXO1 and FOXO3 in regulating Wnt/Beta-catenin signaling pathway and autophagy in pancreatic cancer ENSG00000150907 ENSG00000086991 ENSG00000168036 ENSG00000096717 PMC11077374__F8 FOXO3-FOXM1 axis in regulating drug resistance in pancreatic cancer ENSG00000026508 ENSG00000131828 PMC11855704__F3 Wnt/Beta-catenin pathway in the pathogenesis of obesity ENSG00000162337 ENSG00000168036 ENSG00000185269 ENSG00000168610 ENSG00000171604 ENSG00000130703 ENSG00000087274 PMC6952374__F7 Role of ALK5 and non-canonical androgen signaling in ADPKD ENSG00000162881 ENSG00000173612 PMC11855704__F2 Application of MAPK, PI3K, and JAK/STAT signaling pathways in the pathogenesis of obesity ENSG00000169047 ENSG00000115138 ENSG00000175567 PMC4810556__F1 Inhibition of innate immunity by arenavirus NP and Z ENSG00000174125 ENSG00000159128 ENSG00000213928 ENSG00000276561 ENSG00000142166 ENSG00000111537 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172005 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC7268735__F1 Illustration of CDC25C regulation (Green arrows indicate the enhancement effects and red indicator lines indicate the inhibitory effect) ENSG00000149311 ENSG00000175054 ENSG00000127445 ENSG00000135446 ENSG00000166851 PMC4763866__F1 Schematic pathway of SOCE in neutrophils, leading to activation of the NAPDH oxidase ENSG00000175938 ENSG00000167323 ENSG00000293604 ENSG00000109689 PMC9525271__F8 ADH1C inhibits progression of CRC by ADH1C/PSAT1/ serine metabolic pathway ENSG00000248144 ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC8147992__F2 Fibrotic Events in the Progression of Cholestatic Liver Disease ENSG00000168036 ENSG00000184916 ENSG00000114315 ENSG00000128602 ENSG00000157240 PMC5368180__F1 Nanotechnology-based therapy for prostate cancer ENSG00000026508 ENSG00000168036 ENSG00000167653 PMC7641946__F2 Therapeutic Application of MMEJ for Cancer Treatment ENSG00000175054 PMC7641946__F1 DSB Repair Pathways ENSG00000051180 ENSG00000183624 PMC3540819__F1 Main signaling pathways involved in thyroid carcinogenesis are the MAPK and PI3K-AKT pathway (reproduced with permission) ENSG00000157764 ENSG00000198793 PMC3686815__F9 Regulated Extracellular Choline Acetyltransferase Activity— The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway ENSG00000087085 PMC12226585__F1 ADSCs/ADSCs-exosomes mediates a multidimensional network of mechanisms for IRI repair ENSG00000019991 ENSG00000181019 ENSG00000105550 ENSG00000132646 ENSG00000168036 ENSG00000005381 ENSG00000168610 PMC8616591__F2 Glypican-1 in regulating multiple cellular signaling pathways ENSG00000281324 ENSG00000162337 ENSG00000063660 ENSG00000133067 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000111962 PMC7564666__F6 Protein Expression of Let-7a Target Genes are Altered in a LASP1-Ago2 Interaction-Dependent Manner ENSG00000107562 ENSG00000126353 ENSG00000123908 PMC3940310__F4 Endogenous fatty acid metabolism in the control of hepatic gene transcription ENSG00000134824 ENSG00000149485 ENSG00000197977 ENSG00000169710 ENSG00000164327 ENSG00000124253 PMC6362574__F1 Metabolic engineering strategies for enhancing citric acid production ENSG00000122966 ENSG00000172005 ENSG00000138356 PMC7358452__F8 The in vitro effects of the poly(I:C) ENCPs developed in this study ENSG00000177575 ENSG00000164342 PMC3940310__F2 Pathways for hepatic fatty acid synthesis (FASN) ENSG00000170522 ENSG00000134824 ENSG00000149485 ENSG00000197977 ENSG00000169710 ENSG00000099194 PMC4442291__F2 Schematic summarization for the signaling mechanisms of the antifibrotic effects of H2S ENSG00000086991 ENSG00000172936 ENSG00000136869 ENSG00000096717 PMC4928052__F3 Lipidomic Signatures and Associated Transcriptomic Profiles of Clear Cell Renal Cell Carcinoma ENSG00000110721 ENSG00000185813 ENSG00000018510 ENSG00000173599 ENSG00000292130 ENSG00000116906 PMC6192420__F2 Overview of the vitamin D metabolic pathway ENSG00000105516 ENSG00000019549 ENSG00000137193 ENSG00000134716 ENSG00000135929 PMC9570242__F6 Lithium Treatment Improves Cardiac Dysfunction in Rats Deprived of Rapid Eye Movement Sleep ENSG00000144935 ENSG00000293604 ENSG00000138741 PMC6178832__F2 Molecular features of the JAK-STAT signaling pathway ENSG00000162594 ENSG00000100385 ENSG00000096996 ENSG00000213928 ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000168610 ENSG00000142166 PMC7493825__F3 NLRP6 inflammasome in health and disease ENSG00000174125 ENSG00000174885 ENSG00000172936 ENSG00000293532 PMC7236859__F1 Proposed mechanisms of exercise cardioprotection ENSG00000178568 PMC4805534__F7 Schematic illustration of GSK3B/eIF2BE and mTORC1 signaling in AKT-induced CNS axon regeneration PMC8698915__F4 Antibody and Protein Profiles in Glaucoma: Screening of Biomarkers and Identification of Signaling Pathways ENSG00000039537 ENSG00000113600 ENSG00000291559 ENSG00000288512 ENSG00000189403 ENSG00000166278 ENSG00000182326 PMC8464970__F7 Ergosta-7,9(11),22-trien-3Beta-ol Attenuates Inflammatory Responses via Inhibiting MAPK/AP-1 Induced IL-6/JAK/STAT Pathways and Activating Nrf2/HO-1 Signaling in LPS-Stimulated Macrophage-like Cells ENSG00000137275 ENSG00000102871 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000079999 PMC9189780__F8 DNTTIP1 promotes nasopharyngeal carcinoma metastasis via recruiting HDAC1 to DUSP2 promoter and activating ERK signaling pathway ENSG00000087245 ENSG00000101457 ENSG00000158050 PMC9687482__F4 Linking the Amyloid, Tau, and Mitochondrial Hypotheses of Alzheimer’s Disease and Identifying Promising Drug Targets ENSG00000142192 PMC12079191__F1 Diagram of the ICG-CuET@PLGA-CS-HA (IC@PCH) nanoparticle (NP) synthesis procedure ENSG00000162711 ENSG00000026508 ENSG00000062485 PMC8472292__F2 On the Common Journey of Neural Cells through Ischemic Brain Injury and Alzheimer’s Disease ENSG00000087095 ENSG00000070831 ENSG00000134982 ENSG00000168036 PMC4110625__F1 Model of ER stress-associated inflammation ENSG00000125538 ENSG00000100219 ENSG00000175104 ENSG00000127191 PMC3615671__F2 Metabolic modulation of epigenetics in gliomas ENSG00000171720 ENSG00000138798 ENSG00000146648 PMC3927995__F2 NFAT proteins activate an anergy-inducing program of gene expression ENSG00000065357 ENSG00000291603 ENSG00000111537 ENSG00000213658 ENSG00000078747 ENSG00000177606 ENSG00000096717 ENSG00000164305 ENSG00000106829 PMC7703729__F8 Proposed intracellular mechanism of GRP78 and protein kinase A (PKA) signaling pathway activation by vaspin on basal and IGF-1 and gonadotropin-induced steroid synthesis in ovarian cells ENSG00000082175 ENSG00000138039 PMC8946789__F8 The Leptin-Mediated MAPK/ERK Signaling Pathway on Collagen II Expression in Knee Cartilage of Newborn Male Mice from Obese Maternal Offspring ENSG00000125398 PMC7284105__F2 Feed-forward autocrine YAP activation ENSG00000065361 ENSG00000113070 ENSG00000146648 PMC7284105__F1 Canonical Hippo kinase module ENSG00000150457 ENSG00000131023 PMC7926305__F5 Molecules associated with the canonical pathway (CP) ERK/MAPK signaling in the function of two stages of oocyte development ENSG00000126458 PMC7926305__F4 Common proteins identified in the three replicates of canine in vitro oviductal cell-derived extracellular vesicles that participate in the canonical pathway (CP) ERK/MAPK signaling ENSG00000172680 ENSG00000002330 ENSG00000291971 ENSG00000131196 ENSG00000089159 PMC3336361__F4 Apoptosis pathways PMC3405333__F11 P38 MAPK signaling pathway ENSG00000107669 ENSG00000175104 ENSG00000127191 PMC3405333__F10 ERK/MAPK signaling pathway ENSG00000172680 ENSG00000002330 ENSG00000157764 PMC4887206__F6 Drosophila and vertebrate patched orthologs share a similar cis-regulatory architecture and gene regulatory strategy ENSG00000106571 ENSG00000112039 ENSG00000198125 ENSG00000281857 ENSG00000102974 PMC7166201__F1 PTEN, a PAK1-blocker, interferes with coronavirus –induced PAK1-dependent signalling pathway leading to lung fibrosis ENSG00000108691 ENSG00000130234 ENSG00000149269 PMC4585452__F4 Schematic model of WNT signaling by the FZD receptor(s) ENSG00000087095 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC5745011__F2 Pericytes of the neurovascular unit: Key functions and signaling pathways ENSG00000291971 ENSG00000150907 ENSG00000198793 ENSG00000185591 ENSG00000146648 PMC5745011__F4 Pericytes of the neurovascular unit: Key functions and signaling pathways ENSG00000130300 ENSG00000170365 ENSG00000138795 ENSG00000168214 ENSG00000128917 ENSG00000198435 ENSG00000170558 ENSG00000168036 ENSG00000112715 PMC4810382__F2 EGFR- and ALK-signaling pathways and their respective inhibitors ENSG00000198793 ENSG00000146648 ENSG00000143924 PMC2883292__F2 Signaling through the PI-3 Kinase-Akt pathway ENSG00000117020 ENSG00000002330 ENSG00000291971 ENSG00000169047 ENSG00000198793 PMC7555855__F1 Major targets of amino acids, peptides, and their analogs for the control of skin pigmentation ENSG00000168036 ENSG00000080166 ENSG00000107165 PMC9634190__F1 Association Between Gut Microbiota, Toll-Like Receptors, and Colorectal Cancer ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC9687047__F8 Quercetin Ameliorates Renal Injury and Pyroptosis in Lupus Nephritis through Inhibiting IL-33/ST2 Pathway In Vitro and In Vivo ENSG00000162711 ENSG00000137033 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC3962777__F2 NEW STRATEGIES FOR TRIPLE NEGATIVE BREAST CANCER – DECIPHERING THE HETEROGENEITY ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000109452 ENSG00000198793 ENSG00000263042 ENSG00000146648 ENSG00000139618 PMC2847412__F1 Endoplasmic reticulum stress response as a potential therapeutic target in multiple sclerosis ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000088926 PMC9313042__F1 Interleukin-18 Binding Protein in Immune Regulation and Autoimmune Diseases ENSG00000111537 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000137496 PMC3594951__F1 This figure schematically shows the tyrosine kinase receptors, such as RET, EGFR, FGFR, MET, KIT, VEGFR, PDGFR, and some of their downstream effectors ENSG00000157404 ENSG00000157764 ENSG00000198793 ENSG00000146648 PMC6562585__F4 Regulation of YAP/TAZ in epidermal cells ENSG00000132471 ENSG00000291971 ENSG00000150093 ENSG00000114978 ENSG00000150457 ENSG00000131023 PMC8987729__F8 Temporal Control of the WNT Signaling Pathway During Cardiac Differentiation Impacts Upon the Maturation State of Human Pluripotent Stem Cell Derived Cardiomyocytes ENSG00000159173 ENSG00000123700 ENSG00000135547 ENSG00000135218 ENSG00000141448 ENSG00000285109 ENSG00000183072 ENSG00000156885 ENSG00000089225 ENSG00000106631 ENSG00000131174 ENSG00000092054 ENSG00000164107 PMC4155833__F3 Dual role of Nrf2 in cancer.Notes: As long as it is kept under homeostatic control, Nrf2 activation protects cellular components like DNA from damaging insults arising from acute/temporary oxidative and xenobiotic stress ENSG00000175793 ENSG00000079999 PMC8268779__F1 Anti-Inflammatory Drugs in Patients with Ischemic Heart Disease PMC7460550__F2 Transcriptional Profiling and Biological Pathway(s) Analysis of Type 2 Diabetes Mellitus in a Pakistani Population ENSG00000111537 ENSG00000152669 ENSG00000150907 PMC9252714__F9 Singlet Oxygen, Photodynamic Therapy, and Mechanisms of Cancer Cell Death ENSG00000168040 ENSG00000026103 PMC6456554__F7 Schematic representation of the outlined hypothesis ENSG00000130164 PMC3399530__F2 Gene expression alterations in Rocky Mountain elk infected with chronic wasting disease ENSG00000284832 ENSG00000291560 ENSG00000100285 ENSG00000143878 ENSG00000132639 ENSG00000087460 ENSG00000136167 ENSG00000136541 ENSG00000129757 ENSG00000163914 ENSG00000006747 ENSG00000136235 ENSG00000137575 ENSG00000182667 ENSG00000062485 PMC4514860__F1 Subpathway Analysis based on Signaling-Pathway Impact Analysis of Signaling Pathway ENSG00000095739 ENSG00000134982 ENSG00000167941 ENSG00000113558 PMC2695762__F2 Caspase recruitment domain-containing sensors and adaptors in intestinal innate immunity ENSG00000174125 ENSG00000239732 ENSG00000167207 ENSG00000187796 ENSG00000187554 ENSG00000136869 ENSG00000164342 PMC6671812__F12 Proposed model of IL-18-mediated microglia/astrocyte interaction in the spinal cord ENSG00000136869 ENSG00000137496 PMC4471869__F3 Interleukin-33 in tissue homeostasis, injury and inflammation ENSG00000137033 ENSG00000145777 PMC4514860__F2 Subpathway Analysis based on Signaling-Pathway Impact Analysis of Signaling Pathway ENSG00000095739 ENSG00000167941 ENSG00000113558 PMC9396350__F6 Erythropoietin mediates re-programming of endotoxin-tolerant macrophages through PI3K/AKT signaling and protects mice against secondary infection ENSG00000136869 ENSG00000187266 ENSG00000090376 ENSG00000196363 ENSG00000150630 PMC5617803__F1 The pikromycin (Pik) biosynthetic pathway PMC5832166__F7 TGFB1 signaling in hMSC differentiation ENSG00000122877 ENSG00000291761 ENSG00000100485 ENSG00000104368 PMC7449921__F8 Working model of how MAD2 downregulation promotes asymmetric division and reduces tumor growth and invasion in MKN45 cell line ENSG00000019549 ENSG00000121966 PMC7351433__F1 Simplified scheme of cellular pathway and the targets of MTX ENSG00000228716 ENSG00000100714 ENSG00000136877 ENSG00000035928 ENSG00000137563 ENSG00000118777 PMC7944129__F6 Regulatory network of different pathways ENSG00000113600 ENSG00000110799 ENSG00000073910 ENSG00000010278 ENSG00000166278 ENSG00000117322 ENSG00000254550 ENSG00000126218 ENSG00000112977 ENSG00000173599 ENSG00000175899 ENSG00000080618 ENSG00000171540 ENSG00000062485 PMC2630276__F7 Model for the role of Hedgehog in the recovery of the BMP4-dependent stress erythropoiesis pathway in the spleen ENSG00000139549 ENSG00000163501 PMC6433939__F1 Schematic diagram shows the regulatory non-coding RNAs in NAFLD disease development and progression ENSG00000138823 ENSG00000102007 ENSG00000132326 PMC7797046__F5 Schematic showing the biosynthetic pathway of OHyW in wild type cancer cells (blue area) and taxol resistant strains (red area) ENSG00000198874 ENSG00000162971 PMC152905__F6 Rev1 is essential for DNA damage tolerance and non-templated immunoglobulin gene mutation in a vertebrate cell line ENSG00000070950 PMC9350527__F1 Gut Microbiome-Linked Metabolites in the Pathobiology of Major Depression With or Without Anxiety—A Role for Bile Acids ENSG00000167910 ENSG00000180432 ENSG00000115271 ENSG00000135929 PMC2981456__F1 The estrogen biosynthesis pathway ENSG00000108786 ENSG00000203857 PMC4583600__F2 Cell biology functions and pathways of the genes involved in melanoma susceptibility ENSG00000100811 ENSG00000147162 ENSG00000143970 ENSG00000141568 ENSG00000166848 ENSG00000092330 ENSG00000102977 ENSG00000012048 ENSG00000292096 ENSG00000132604 ENSG00000171456 ENSG00000135446 ENSG00000164362 ENSG00000147601 ENSG00000128513 ENSG00000164916 PMC317073__F7 Regulation of TNF-R1signaling pathways during apoptosis ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC8463866__F1 Production and Function of Endogenous Interleukin-10 in Intestinal Epithelial Cells and Gut Homeostasis ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC3315606__F1 Roles for prions and protein-only inheritance in cancer PMC7463967__F4 Network of known interactions between RTKs and the Hippo pathway ENSG00000129474 ENSG00000138798 ENSG00000169047 ENSG00000150457 ENSG00000131023 ENSG00000168610 ENSG00000133216 ENSG00000153208 ENSG00000078747 ENSG00000163914 ENSG00000146648 ENSG00000115419 ENSG00000178568 PMC6139616__F1 Hepatic lipid metabolic pathways investigated in this study ENSG00000131473 ENSG00000042832 ENSG00000113161 ENSG00000169710 ENSG00000113360 PMC7033839__F1 Proposed mechanism of statins, colchicine, and aspirin on the reduction of radiation‐associated cardiovascular disease (RACVD) ENSG00000163914 ENSG00000113520 PMC11172987__F2 Host Cell Death and Modulation of Immune Response against Mycobacterium tuberculosis Infection ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC3344210__F4 The effects of curcumin on the TNFA receptor and its downstream signaling pathway ENSG00000099330 ENSG00000150782 ENSG00000115904 ENSG00000127191 PMC7463967__F1 Illustration of the Hippo pathway and its regulation in mammalian cells ENSG00000198670 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC4410181__F2 Control of regulatory T cell lineage commitment and maintenance ENSG00000185591 ENSG00000049768 PMC9795026__F1 Toolkit for plant lipid engineering: Surveying the efficacies of lipogenic factors for accumulating specialty lipids ENSG00000173599 ENSG00000198670 ENSG00000121053 ENSG00000026103 PMC6494966__F1 Schematic depiction of processes and pathways involved in iron homeostasis and regulation in the brain ENSG00000142192 ENSG00000130164 ENSG00000118564 PMC5239436__F1 Autophagy complexes cell death by necroptosis ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC6091082__F3 The applied conditions on the expression of central metabolism genes ENSG00000159224 ENSG00000197713 ENSG00000073578 ENSG00000145020 ENSG00000140464 ENSG00000129744 ENSG00000026103 PMC5992122__F1 Universal Pathway for the Biosynthesis of Coenzyme A and Associated DiseasesIn green are indicated genes encoding either cytosolic or mitochondrial isoforms ENSG00000138621 ENSG00000127125 PMC8572801__F7 Mucin 20 modulates proteasome capacity through c‐Met signalling to increase carfilzomib sensitivity in mantle cell lymphoma ENSG00000277753 ENSG00000019991 ENSG00000132963 PMC5204264__F2 Proteome complexity and the forces that drive proteome imbalance ENSG00000163435 ENSG00000101751 ENSG00000178573 ENSG00000136997 ENSG00000106459 PMC5968632__F2 Pathways significantly enriched for: (A) Loci associated with the vertical cup-disc ratio, cup area and intraocular pressure (P-value <7.0 × 10-6 in the GWAS) ENSG00000112559 ENSG00000074181 ENSG00000087903 ENSG00000161202 ENSG00000137801 PMC8471715__F2 Oxidative Stress, Testicular Inflammatory Pathways, and Male Reproduction ENSG00000172936 ENSG00000106459 ENSG00000167419 PMC8293073__F5 BMP Signaling in Osteoclast Regulation ENSG00000170365 ENSG00000175104 PMC6693242__F1 The autophagy pathways in endothelial cells ENSG00000172339 PMC12245983__F5 PI3K/Akt/mTOR signalling pathway is activated upon binding of growth factor to receptor tyrosine kinase (RTK), which results in autophosphorylation of tyrosine residues and recruits phosphatidyl-inositol-3-kinase (PI3K) to cell membrane ENSG00000198793 PMC12245983__F4 Notch signalling pathway upon activation, Notch receptors release signal-transducing Notch intracellular domain (NICD), which moves into the nucleus where it interacts with CSL nuclear proteins, forming CSL-NICD transcriptional complex ENSG00000148400 ENSG00000114315 PMC11994588__F3 Liquid-Liquid Phase Separation (LLPS) in Cellular Signal Transduction Pathways ENSG00000134982 ENSG00000198793 PMC8570367__F1 Inhibition of glutaminolysis in combination with other therapies to improve cancer treatment ENSG00000065833 ENSG00000115419 PMC6586788__F1 Hypoxia and aging ENSG00000100473 ENSG00000198793 PMC6820556__F6 Model summarizing the ABeta-induced actin cytoskeletal abnormalities via SHIP2-PI(3,4)P2-ARAP3-RhoA signaling pathway ENSG00000124102 PMC10915940__F1 Canonical signaling pathway of interferon-gamma ENSG00000159128 ENSG00000115415 ENSG00000027697 PMC12245983__F7 Exploring resveratrol’s inhibitory potential on lung cancer stem cells: a scoping review of mechanistic pathways across cancer models ENSG00000198793 ENSG00000168036 ENSG00000114315 PMC8505556__F2 Tumour suppressor functions of BAP1, Merlin and p16INK4a/p14ARF proteins ENSG00000012048 ENSG00000198901 ENSG00000163930 ENSG00000135446 ENSG00000136997 ENSG00000150457 ENSG00000131023 ENSG00000139618 PMC12245983__F6 Hedgehog pathway is mediated by ligand HH, upon binding to PTCH the SMO inhibition is weakened, allowing its translocation to plasma membrane leading to HH pathway activation ENSG00000106571 ENSG00000128602 PMC7403459__F1 Two primary pathways produce ceramides in cells: (a) de novo synthesis (b) re-acylation of sphingosine (salvage pathway) ENSG00000139624 ENSG00000154227 ENSG00000143418 PMC9539794__F6 Triptolide in the treatment of systemic lupus erythematosus - regulatory effects on miR-146a in B cell TLR7 signaling pathway in mice ENSG00000172936 ENSG00000184216 PMC3884200__F5 Effects of CYP2S1 depletion on mTOR signaling ENSG00000140992 ENSG00000177169 ENSG00000168209 ENSG00000104365 ENSG00000157764 ENSG00000083290 ENSG00000198793 ENSG00000169047 ENSG00000164327 ENSG00000141564 ENSG00000112715 ENSG00000187840 ENSG00000266173 ENSG00000135932 ENSG00000204673 PMC7071019__F2 Cellular response: APCs and T-lymphocytes ENSG00000134982 PMC12245885__F2 Major mechanisms of platelet aggregation ENSG00000110799 PMC4698632__F8 Telomerase reverse transcriptase acts in a feedback loop with NFKB pathway to regulate macrophage polarization in alcoholic liver disease ENSG00000125538 ENSG00000164362 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 ENSG00000007171 PMC6070353__F2 Oncogenic Signaling Pathways in The Cancer Genome Atlas ENSG00000121989 ENSG00000109452 ENSG00000157404 ENSG00000149930 ENSG00000281324 ENSG00000141551 ENSG00000162337 ENSG00000160551 ENSG00000135090 ENSG00000134982 ENSG00000196782 ENSG00000164327 ENSG00000141564 ENSG00000124762 ENSG00000183765 ENSG00000122025 ENSG00000065717 ENSG00000187957 ENSG00000184675 ENSG00000143801 ENSG00000073614 ENSG00000155011 ENSG00000136997 ENSG00000123933 ENSG00000108375 ENSG00000174197 ENSG00000196498 ENSG00000116990 ENSG00000105810 ENSG00000077782 ENSG00000139687 ENSG00000140443 ENSG00000196712 ENSG00000109670 ENSG00000113645 ENSG00000134376 ENSG00000166341 ENSG00000101109 ENSG00000156076 ENSG00000292149 ENSG00000105568 ENSG00000106829 ENSG00000197070 ENSG00000110395 ENSG00000065526 ENSG00000146648 ENSG00000178568 ENSG00000105722 ENSG00000198793 ENSG00000115904 ENSG00000168036 ENSG00000169032 ENSG00000047936 ENSG00000104332 ENSG00000179295 ENSG00000083857 ENSG00000070444 ENSG00000186575 ENSG00000129757 ENSG00000120057 ENSG00000104371 ENSG00000183579 ENSG00000143622 ENSG00000123374 ENSG00000108788 ENSG00000135503 ENSG00000281178 ENSG00000005339 ENSG00000157764 ENSG00000065361 ENSG00000114978 ENSG00000106483 ENSG00000184916 ENSG00000131023 ENSG00000074219 ENSG00000079999 ENSG00000149311 ENSG00000066468 ENSG00000177189 ENSG00000160867 ENSG00000135446 ENSG00000148204 ENSG00000050165 ENSG00000134853 ENSG00000213347 ENSG00000168646 ENSG00000198625 PMC7981362__F1 Insulin receptor substance-1 modulating PI3K/Akt insulin signaling pathway in Alzheimer’s disease ENSG00000169047 ENSG00000198793 ENSG00000119912 PMC8945030__F1 Gene Variants Involved in Nonsense-Mediated mRNA Decay Suggest a Role in Autism Spectrum Disorder ENSG00000070756 ENSG00000105771 ENSG00000134815 ENSG00000108349 ENSG00000151461 ENSG00000189266 ENSG00000114127 ENSG00000167447 ENSG00000205937 ENSG00000157106 ENSG00000026103 PMC7981362__F2 Insulin receptor substance-1 modulating PI3K/Akt insulin signaling pathway in Alzheimer’s disease ENSG00000169047 ENSG00000198793 PMC6476855__F1 Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000172936 PMC1088370__F1 Topologies of the three networks ENSG00000134982 ENSG00000198125 ENSG00000117399 PMC4150610__F2 Interferon-inducible effector mechanisms in cell-autonomous immunity ENSG00000143553 ENSG00000183735 ENSG00000117228 ENSG00000213512 ENSG00000057663 ENSG00000007171 PMC4113681__F1 Representative regulators of the Sprouty cellular content at transcriptional and post-translational level irrespective of the Sprouty isoform and cell type ENSG00000110395 ENSG00000181788 ENSG00000070831 ENSG00000136997 ENSG00000168036 ENSG00000062485 PMC4113681__F2 The Sprouty-mediated regulation of cell proliferation, differentiation, and survival irrespective of the Sprouty isoform and cell type ENSG00000002330 ENSG00000110395 ENSG00000136997 PMC11185840__F4 Sphingolipids and complement components signaling in glioblastoma ENSG00000162711 ENSG00000137168 ENSG00000099968 ENSG00000170989 ENSG00000168610 ENSG00000183018 ENSG00000121966 PMC11185840__F3 Activation of the complement system and its functions ENSG00000162711 ENSG00000039537 ENSG00000113600 ENSG00000198793 ENSG00000117335 ENSG00000166278 PMC11185840__F2 Sphingolipid metabolic pathway ENSG00000100422 ENSG00000174607 PMC9293722__F6 Retinoic acid can improve autophagy through depression of the PI3K-Akt-mTOR signaling pathway via RARA to restore spermatogenesis in cryptorchid infertile rats ENSG00000146857 ENSG00000139351 PMC12130998__F7 Supposed mechanism on the dual role of pB318L in viral replication ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000114030 ENSG00000142166 PMC3175563__F6 Proposed mechanism of mechanical stress–induced activation of EGFR pathway in murine tracheal epithelial cells ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000146648 PMC8572027__F2 Anti-Inflammatory Effects of Curcumin in the Inflammatory Diseases: Status, Limitations and Countermeasures ENSG00000162711 ENSG00000178573 ENSG00000125538 ENSG00000175104 PMC5486373__F1 MiRNAs involved in the regulation of autophagy-related signaling pathways ENSG00000177169 ENSG00000120875 ENSG00000198793 ENSG00000110931 ENSG00000198931 ENSG00000069509 ENSG00000164327 ENSG00000141564 ENSG00000175567 ENSG00000168610 ENSG00000164104 ENSG00000124762 ENSG00000136048 ENSG00000175634 ENSG00000138166 ENSG00000137203 ENSG00000189403 ENSG00000123374 ENSG00000078237 ENSG00000096717 ENSG00000140443 PMC2949025__F2 Correlations (Spearman) of biomass growth (biom) and lignin levels with transcript abundance of specific monolignol biosynthetic genes in a interspecific pseudo-backcross pedigree of Populus (family 52-124) ENSG00000084774 PMC7565022__F1 Hedgehog (HH) signaling pathway ENSG00000180447 ENSG00000106571 ENSG00000128602 PMC7565022__F4 Protein arginine methyl transferase (PRMT)-mediated modulation of glioma-associated oncogene (GLI) 1 or GLI2 activity ENSG00000180447 ENSG00000078747 ENSG00000126457 ENSG00000132600 ENSG00000133961 PMC3561376__F6 Whole Genome Gene Expression Analysis Reveals Casiopeína-Induced Apoptosis Pathways ENSG00000102871 ENSG00000120868 ENSG00000168040 ENSG00000127191 PMC3561376__F5 Whole Genome Gene Expression Analysis Reveals Casiopeína-Induced Apoptosis Pathways ENSG00000171855 ENSG00000134460 ENSG00000182568 ENSG00000148926 ENSG00000099860 ENSG00000171791 ENSG00000168040 ENSG00000184292 ENSG00000049768 ENSG00000164305 ENSG00000124762 ENSG00000165684 ENSG00000278268 ENSG00000115415 ENSG00000173757 ENSG00000136997 ENSG00000130222 ENSG00000164362 ENSG00000164136 ENSG00000184371 ENSG00000134644 ENSG00000100985 ENSG00000148154 ENSG00000064012 PMC4514086__F3 Cytosolic RNA and DNA-induced type I IFN signaling pathway and its regulators ENSG00000132109 ENSG00000119401 ENSG00000163565 ENSG00000127191 ENSG00000169871 ENSG00000276561 ENSG00000057663 ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000140455 ENSG00000123609 ENSG00000160703 ENSG00000107201 ENSG00000131323 ENSG00000175104 ENSG00000145782 ENSG00000121060 PMC4644426__F9 Syncytin-1 alterations triggered placental trophoblast cell cycle changes ENSG00000135446 PMC4299200__F1 De novo and salvage pathway synthesis of dTMP in the nucleus ENSG00000284320 ENSG00000228716 ENSG00000100714 ENSG00000116984 PMC6814454__F2 Substrates of PD enzymes identified by proteomics.(A) The PINK1-parkin mitophagy pathway ENSG00000158828 PMC4064951__F2 Resistance to BRAF inhibitors: intrinsic and extrinsic mechanisms.Notes: Multiple different mechanisms have been described in resistance to BRAF inhibitors ENSG00000124102 ENSG00000135446 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC3410756__F1 Folate mediated one-carbon cycle ENSG00000228716 ENSG00000124275 PMC4973992__F6 High Resolution Genomic Scans Reveal Genetic Architecture Controlling Alcohol Preference in Bidirectionally Selected Rat Model ENSG00000113262 ENSG00000100151 ENSG00000179603 ENSG00000124493 ENSG00000164082 ENSG00000111371 ENSG00000115419 PMC3723115__F2 Canonical TGFB signaling within distinct cell types located in tumor microenvironments ENSG00000170365 PMC8717053__F1 Antiviral effect of antineoplastic agents inhibiting mTOR/PI3K signaling pathway in SARS-CoV-2 infection in cancer patients ENSG00000130234 ENSG00000198793 PMC4452069__F1 PI3K/Akt/mTOR signaling cascade ENSG00000198793 PMC8465097__F5 Differences in Acid Stress Response of Lacticaseibacillus paracasei Zhang Cultured from Solid-State Fermentation and Liquid-State Fermentation ENSG00000144063 ENSG00000090316 ENSG00000145321 ENSG00000127311 PMC9361020__F1 Endoplasmic reticulum stress in innate immune cells - a significant contribution to non-alcoholic fatty liver disease ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8536552__F7 Heat stress inhibits TLR4-NFKB and TLR4-TBK1 signaling pathways in broilers infected with Salmonella Typhimurium ENSG00000162711 ENSG00000183735 ENSG00000125538 ENSG00000136869 PMC5969225__F3 Hh–Gli signalling in myofibroblasts ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC8343457__F1 Cerebrospinal fluid metabolomics: detection of neuroinflammation in human central nervous system disease ENSG00000036473 PMC4410310__F3 Gallus Gallus retinol metabolic pathway from KEGG ENSG00000121207 ENSG00000116745 ENSG00000284807 ENSG00000171234 ENSG00000006757 PMC2822520__F7 A working model for endosomal transport involving CLC-5 and KIF3B interaction in polarized cells ENSG00000101350 PMC8226833__F3 Resveratrol Production in Yeast Hosts: Current Status and Perspectives PMC6650384__F2 Changes in placental signaling in IUGR ENSG00000144895 ENSG00000140443 PMC5708160__F1 Strategies for Comparing Metabolic Profiles: Implications for the Inference of Biochemical Mechanisms from Metabolomics Data ENSG00000196839 ENSG00000137198 ENSG00000198931 PMC3160197__F1 Crucial role of EGF signalling augments healthy lifespan in worms ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC3882527__F5 Ingenuity pathway analysis (IPA)-identified top networks affected by Cd-induced oxidation of proteins ENSG00000163399 ENSG00000163914 ENSG00000136068 PMC5804490__F3 Gene Expression, and Fatigue in Puerto Rican Men during Radiotherapy for Prostate Cancer: an exploratory study ENSG00000095585 ENSG00000275723 ENSG00000027075 ENSG00000047410 ENSG00000105369 ENSG00000142192 ENSG00000152495 ENSG00000169499 ENSG00000010810 ENSG00000117602 PMC4896164__F2 Main pathways regulated by the BCR-ABL1 protein ENSG00000099942 ENSG00000179348 PMC5444348__F1 The IFN-1 > BID > ROS pathway connects DNA damage with hyper-proliferation and malfunction of haematopoietic stem/progenitor cells (HSPCs) ENSG00000149311 ENSG00000175054 ENSG00000164430 ENSG00000285121 PMC4438523__F3 “Actin Cytoskeleton Signaling” pathway highlighting differentially expressed genes of birds affected with Wooden Breast myopathy ENSG00000038382 ENSG00000172380 ENSG00000175866 ENSG00000170458 ENSG00000138443 ENSG00000138798 ENSG00000181104 ENSG00000089159 PMC9405349__F7 GLUT3 Promotes Epithelial–Mesenchymal Transition via TGFB/JNK/ATF2 Signaling Pathway in Colorectal Cancer Cells ENSG00000170558 PMC6785638__F5 Calcium signaling pathway is overrepresented in the specific differentially expressed genes altered by alfalfa intervention during the preweaning period ENSG00000109819 ENSG00000288499 ENSG00000130528 ENSG00000166501 ENSG00000007171 ENSG00000069667 PMC7867281__F1 Principal functional interactions between lncRNA HOTAIR and different microRNAs ENSG00000167601 ENSG00000275385 ENSG00000198793 ENSG00000276644 ENSG00000105639 ENSG00000168610 ENSG00000108691 ENSG00000074181 ENSG00000135446 ENSG00000276051 ENSG00000143322 ENSG00000105810 ENSG00000179399 PMC9453976__F3 Emerging ROS-Modulating Technologies for Augmentation of the Wound Healing Process ENSG00000178573 ENSG00000125538 ENSG00000096717 ENSG00000175104 PMC7826734__F1 Role of VEGF signaling in OSCC ENSG00000138798 ENSG00000168610 ENSG00000277943 PMC11547105__F5 Comparative Metabolomics to Unravel the Biochemical Mechanism Associated with Rancidity in Pearl Millet (Pennisetum glaucum L.) ENSG00000173599 ENSG00000026103 PMC6037329__F2 Cholesterol and Bile Acid -Mediated Regulation of Autophagy in Fatty Liver Diseases and Atherosclerosis ENSG00000138075 ENSG00000130164 ENSG00000042832 ENSG00000167910 ENSG00000160179 ENSG00000143921 PMC9361020__F3 Endoplasmic reticulum stress in innate immune cells - a significant contribution to non-alcoholic fatty liver disease ENSG00000125538 ENSG00000175104 PMC2223843__F2 TLR3 signaling pathways ENSG00000164342 PMC4887998__F7 Enhanced immunoregulation of mesenchymal stem cells by IL-10-producing type 1 regulatory T cells in collagen-induced arthritis ENSG00000178860 ENSG00000115415 ENSG00000164342 PMC6880379__F3 The Atm-Aim2 axis in neuroinflammation and neurodegeneration ENSG00000149311 ENSG00000163568 ENSG00000125538 PMC8714844__F3 Recent Progress in Lymphangioma PMC5951909__F8 NDRG3 lowers the metastatic potential in prostate cancer as a feedback controller of hypoxia-inducible factors ENSG00000134086 ENSG00000101079 PMC7352956__F3 Regulation of the Hippo/YAP signaling pathway in non-small-cell lung cancer (NSCLC) ENSG00000186575 ENSG00000138798 ENSG00000168036 ENSG00000150457 ENSG00000128602 ENSG00000146648 ENSG00000131023 PMC7650612__F2 Influence diagram of the molecular interactions implemented in the model ENSG00000113905 ENSG00000065361 ENSG00000138798 ENSG00000178568 PMC6109711__F3 cAMP/PKA network ENSG00000138083 ENSG00000135409 ENSG00000064393 ENSG00000168036 ENSG00000189403 ENSG00000164120 ENSG00000095794 ENSG00000127616 PMC3127162__F8 E3 ubiquitin ligase-dependent and E3 ligase-independent roles of Rad18 in tolerance of bulky DNA lesions (left) and replication-associated DSB (right) ENSG00000144554 ENSG00000108384 ENSG00000070950 ENSG00000130997 PMC7459983__F3 Schematic description of genetic abnormalities (mutations or upregulation) associated with secondary off-target resistance to FLT3 inhibitors ENSG00000122025 ENSG00000167601 ENSG00000101972 ENSG00000171456 ENSG00000157764 ENSG00000110395 ENSG00000198793 ENSG00000137193 ENSG00000179295 PMC8034476__F2 Mechanism and regulatory axis of PTHR1 in osteosarcoma ENSG00000170961 ENSG00000138795 ENSG00000062716 PMC8779408__F2 Nek2 Kinase Signaling in Malaria, Bone, Immune and Kidney Disorders to Metastatic Cancers and Drug Resistance: Progress on Nek2 Inhibitor Development ENSG00000117650 ENSG00000011523 ENSG00000166851 ENSG00000163507 PMC5010489__F2 Molecular mechanisms of innate immune inhibition by non-segmented negative-sense RNA viruses ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000131323 ENSG00000276561 ENSG00000142166 PMC6307528__F5 Crosstalk between the Rho kinase and BMP-2 signaling pathways ENSG00000170365 ENSG00000163914 PMC8217435__F1 Inhibition of the IFN Response by Bluetongue Virus: The Story So Far ENSG00000183735 ENSG00000159128 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000185436 ENSG00000185745 ENSG00000027697 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC2585009__F7 HIV-1 Activates Macrophages Independent of Toll-Like Receptors ENSG00000183735 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000127666 ENSG00000184216 ENSG00000164342 PMC8103215__F4 Beta-Caryophyllene Ameliorates MSU-Induced Gouty Arthritis and Inflammation Through Inhibiting NLRP3 and NFKB Signal Pathway: In Silico and In Vivo ENSG00000112977 ENSG00000156026 ENSG00000137392 ENSG00000073910 PMC7838888__F1 Representative long non-coding RNAs (lncRNAs) in diffuse large B-cell lymphoma (DLBCL) ENSG00000136997 ENSG00000137656 PMC8217435__F3 Inhibition of the IFN Response by Bluetongue Virus: The Story So Far ENSG00000183735 ENSG00000088888 ENSG00000172936 ENSG00000131323 ENSG00000276561 ENSG00000164342 PMC2585009__F4 HIV-1 Activates Macrophages Independent of Toll-Like Receptors ENSG00000150594 ENSG00000102871 ENSG00000117152 ENSG00000166484 ENSG00000243509 ENSG00000139625 ENSG00000127191 ENSG00000173327 ENSG00000114738 ENSG00000141503 ENSG00000115415 ENSG00000149269 ENSG00000185591 ENSG00000077782 ENSG00000089022 ENSG00000164086 PMC8217435__F4 Inhibition of the IFN Response by Bluetongue Virus: The Story So Far ENSG00000183735 ENSG00000159128 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000185436 ENSG00000027697 ENSG00000276561 ENSG00000142166 PMC2364238__F1 SMAD4 is a predictive marker for 5-fluorouracil-based chemotherapy in patients with colorectal cancer ENSG00000137834 PMC2895628__F5 Mode of miRNAs that regulate adipogenesis by modulating the canonical Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC6266631__F6 KDM5A function and its expression control in proliferating NPC and differentiating astrocyte ENSG00000242689 ENSG00000073614 ENSG00000138798 ENSG00000131095 ENSG00000168610 PMC7753287__F2 Diverse roles of long non‐coding RNAs in viral diseases ENSG00000169245 ENSG00000105397 ENSG00000153094 ENSG00000173039 ENSG00000184371 ENSG00000172936 ENSG00000136869 ENSG00000074266 ENSG00000178691 ENSG00000142166 PMC12222062__F8 Oxytropis falcata bunge extract combined with black soybean oil ameliorates DNCB-induced atopic dermatitis-like skin inflammation ENSG00000171720 ENSG00000113520 PMC4000654__F1 Physiological and physiopathological UPR activated pathways in B cells ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC9476852__F6 Chinese herbal formula shen-ling-bai-zhu-san to treat chronic gastritis: Clinical evidence and potential mechanisms ENSG00000167601 ENSG00000019991 ENSG00000002330 ENSG00000090402 ENSG00000101146 ENSG00000168610 ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000113905 ENSG00000169291 ENSG00000186716 ENSG00000104894 ENSG00000128342 ENSG00000146648 ENSG00000196712 ENSG00000127948 PMC9607181__F1 Important Hormones Regulating Lipid Metabolism ENSG00000170522 ENSG00000169710 PMC7795602__F1 Regulatory functions of Mediator complex in biotic and abiotic stress responses ENSG00000184634 ENSG00000132964 ENSG00000108510 PMC9281252__F4 Molecular perspective on targeted therapy in breast cancer: a review of current status ENSG00000140443 PMC5438978__F1 Regulation of IL-1/18 production and current IL-1/18 antagonists ENSG00000162711 ENSG00000140368 ENSG00000137496 PMC4997237__F14 Peripheral Blood Cell Gene Expression Diagnostic for Identifying Symptomatic Transthyretin Amyloidosis Patients: Male and Female Specific Signatures ENSG00000131469 ENSG00000291931 ENSG00000166441 ENSG00000089157 ENSG00000136942 ENSG00000100664 ENSG00000174444 ENSG00000149311 ENSG00000163435 ENSG00000063177 ENSG00000174748 ENSG00000144895 ENSG00000102034 ENSG00000175390 PMC8000424__F5 Effective graph reveals redundancy, canalization, and control pathways in biochemical regulation and signaling ENSG00000121335 ENSG00000002330 ENSG00000136997 ENSG00000118515 ENSG00000129514 ENSG00000123374 ENSG00000275624 ENSG00000171791 ENSG00000118971 PMC4673177__F8 Cerebral endothelial cell function by TGFB in glioblastoma: VEGF-dependent angiogenesis versus endothelial mesenchymal transition ENSG00000124216 ENSG00000110799 ENSG00000170558 ENSG00000184113 PMC3734905__F2 Germline syndromes associated with the Ras signaling pathway.Schematic diagram showing the GM-CSF receptor spanning the phospholipid bilayer ENSG00000110395 ENSG00000196712 PMC7943547__F1 Role model of intracellular HYOU1 in tumor development ENSG00000128272 ENSG00000144895 PMC3241690__F7 Crosstalk between Nuclear Factor I-C and Transforming Growth FactorB1 Signaling Regulates Odontoblast Differentiation and Homeostasis ENSG00000198742 PMC3967109__F2 Target gene set within Alzheimer’s disease environmental network ENSG00000107859 ENSG00000138613 ENSG00000170348 ENSG00000165055 ENSG00000198598 PMC9133606__F3 Phytochemicals in Skin Photoprotection via Regulation of Nrf2 ENSG00000181019 ENSG00000149968 ENSG00000100985 ENSG00000079999 PMC9239764__F9 ARL4C Regulates the Progression of Clear Cell Renal Cell Carcinoma by Affecting the Wnt/Beta-Catenin Signaling Pathway ENSG00000170558 ENSG00000168036 PMC9133606__F2 Phytochemicals in Skin Photoprotection via Regulation of Nrf2 ENSG00000181019 ENSG00000173599 PMC9602067__F4 Novel De Novo NFKBIA Missense Mutation Associated to Ectodermal Dysplasia with Dysgammaglobulinemia ENSG00000135960 ENSG00000186716 PMC8740228__F4 Comparative Proteomic Profiling Identifies Reciprocal Expression of Mitochondrial Proteins Between White and Gray Matter Lesions From Multiple Sclerosis Brains ENSG00000145362 ENSG00000125814 ENSG00000070831 ENSG00000134982 ENSG00000197746 ENSG00000161203 ENSG00000120885 ENSG00000154016 ENSG00000105402 ENSG00000196961 ENSG00000041982 ENSG00000163914 ENSG00000006451 ENSG00000183020 ENSG00000220205 ENSG00000152556 PMC8994495__F6 Network diagram of “component-target-pathway” ENSG00000142192 ENSG00000082175 ENSG00000087085 ENSG00000146648 PMC9641012__F7 Quantitative proteomic analysis reveals the molecular mechanism of the Yesso scallop (Patinopecten yessoensis) in response to Polydora infection ENSG00000003056 ENSG00000149269 PMC11540618__F7 Lipid metabolic profiling and diagnostic model development for hyperlipidemic acute pancreatitis ENSG00000173599 ENSG00000015285 PMC6627153__F6 PCOS–disease subnetwork 28 ENSG00000103266 ENSG00000050748 ENSG00000100345 ENSG00000170606 ENSG00000174483 ENSG00000086758 ENSG00000138686 ENSG00000011304 ENSG00000146592 ENSG00000177606 ENSG00000170653 ENSG00000092203 ENSG00000138668 ENSG00000214413 ENSG00000165533 ENSG00000125124 PMC6627153__F3 PCOS–disease subnetwork 8 ENSG00000277909 ENSG00000005339 ENSG00000117697 ENSG00000105176 ENSG00000143228 ENSG00000161888 ENSG00000137812 ENSG00000145604 ENSG00000005175 ENSG00000012048 ENSG00000159216 ENSG00000084676 ENSG00000122952 PMC6627153__F2 PCOS–disease subnetwork 1 ENSG00000110700 ENSG00000280831 ENSG00000291931 ENSG00000223367 ENSG00000105193 ENSG00000197728 ENSG00000162692 ENSG00000278270 ENSG00000083845 PMC6627153__F4 PCOS–disease subnetwork 26 ENSG00000224320 ENSG00000186818 PMC4734217__F1 Pim-1 kinase as cancer drug target: An update ENSG00000002330 ENSG00000136997 ENSG00000137193 ENSG00000173039 ENSG00000122565 ENSG00000171791 ENSG00000168610 ENSG00000131196 PMC7996988__F8 Induction of interferonB and interferon signaling by TRAIL and Smac mimetics via caspase-8 in breast cancer cells ENSG00000213928 ENSG00000115415 ENSG00000142166 PMC3218720__F2 Receptors that sense danger signals released from neighboring injured retinal pigment epithelial (RPE) cells ENSG00000239732 ENSG00000125538 ENSG00000189403 ENSG00000136869 PMC3393662__F8 Shp2 Activates Fyn and Ras to Regulate RBL-2H3 Mast Cell Activation following FcERI Aggregation ENSG00000033327 ENSG00000213658 ENSG00000010810 PMC514952__F1 Mechanism of endocytic downregulation of RTKs ENSG00000102189 ENSG00000074319 PMC2841320__F6 ZIP4 Regulates Pancreatic Cancer Cell Growth by Activating IL-6/STAT3 Pathway via Zinc Finger Transcription Factor CREB ENSG00000173599 ENSG00000168610 PMC6003649__F10 Signalling pathways involved in the intervention effects of PZC, PZD and PZE on TIF ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4630171__F12 Proposed model ENSG00000162552 ENSG00000138795 ENSG00000162337 ENSG00000168036 PMC9516113__F1 Defining and targeting patterns of T cell dysfunction in inborn errors of immunity ENSG00000291603 ENSG00000198793 PMC11526956__F1 Distribution of dNdS values for genes encoding proteins involved in upstream and downstream NFLs across various signaling networks ENSG00000050165 ENSG00000168036 ENSG00000150457 ENSG00000168646 ENSG00000131023 PMC3388714__F2 Layers of DC-mediated tolerance PMC11814332__F9 Schematic depicting the role of CerS6 in ceramide metabolism and innate immune responses ENSG00000183735 ENSG00000172292 ENSG00000164430 PMC8345475__F1 Review of the Molecular Genetics of Basal Cell Carcinoma; Inherited Susceptibility, Somatic Mutations, and Targeted Therapeutics ENSG00000164690 ENSG00000128602 PMC3423345__F2 Early Second Trimester Maternal Plasma Choline and Betaine Are Related to Measures of Early Cognitive Development in Term Infants ENSG00000228716 ENSG00000016391 PMC6423516__F2 Lysosomes Mediate Benefits of Intermittent Fasting in Cardiometabolic Disease: The Janitor is the Undercover Boss ENSG00000177169 ENSG00000112561 ENSG00000145782 ENSG00000057663 PMC8345475__F2 Review of the Molecular Genetics of Basal Cell Carcinoma; Inherited Susceptibility, Somatic Mutations, and Targeted Therapeutics ENSG00000137265 PMC9692235__F6 Transducin-like enhancer of split (TLE) family proteins in tumorigenesis and immune regulation ENSG00000188290 ENSG00000122025 ENSG00000136997 ENSG00000107807 ENSG00000083799 ENSG00000171791 ENSG00000114315 ENSG00000106829 PMC3288319__F4 Phytoestrogens on ECs and VSMCs ENSG00000145321 PMC6423516__F3 Lysosomes Mediate Benefits of Intermittent Fasting in Cardiometabolic Disease: The Janitor is the Undercover Boss ENSG00000177169 ENSG00000114416 ENSG00000158828 ENSG00000112561 ENSG00000096088 ENSG00000132326 ENSG00000124523 ENSG00000096717 ENSG00000142082 ENSG00000089163 PMC8146591__F2 Glutathione S-Transferases in Cancer ENSG00000198793 ENSG00000127191 PMC9692235__F2 Transducin-like enhancer of split (TLE) family proteins in tumorigenesis and immune regulation ENSG00000012048 ENSG00000136997 ENSG00000176165 ENSG00000128965 PMC7900568__F1 cGAS-STING pathway and type-I IFN signaling ENSG00000183735 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC3507808__F1 Metabolites and their metabolic pathway networks measured by the Arg/Thiol Redox Metabolomics Assay ENSG00000122966 PMC3863464__F6 Putative CA-mediated inhibitory pathway of inflammatory signaling events ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC6213474__F2 Sonic Hedgehog (SHH) molecule or SHH secreted on extracellular vesicles (EVs) mediated functional improvement of endothelial progenitor cells (EPCs) ENSG00000164690 PMC9569554__F4 Hypoxia-Inducible Factors Signaling in Osteogenesis and Skeletal Repair ENSG00000178860 ENSG00000196411 ENSG00000198793 PMC12188669__F2 YOD1 in regulating multiple cellular signaling pathways ENSG00000180667 ENSG00000069869 ENSG00000078747 ENSG00000175104 PMC6213474__F1 Canonical and Non-Canonical Sonic hedgehog (SHH) signaling pathway in endothelial progenitor cells (EPCs) and endothelial cells (ECs) ENSG00000087245 ENSG00000164690 ENSG00000128602 PMC9569554__F3 Hypoxia-Inducible Factors Signaling in Osteogenesis and Skeletal Repair ENSG00000118972 ENSG00000187266 PMC4323349__F1 Transgenic Mouse Models for Alcohol Metabolism, Toxicity and Cancer ENSG00000130649 ENSG00000023909 PMC9569554__F5 Hypoxia-Inducible Factors Signaling in Osteogenesis and Skeletal Repair ENSG00000178860 ENSG00000170365 ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC12188669__F6 Disease signaling by YOD1: potential implications for therapeutic strategies ENSG00000162711 ENSG00000180667 ENSG00000078747 ENSG00000168036 ENSG00000253352 PMC12188669__F5 Roles of YOD1 in Diseases ENSG00000100811 ENSG00000123999 ENSG00000180667 ENSG00000069869 ENSG00000167207 ENSG00000078747 ENSG00000100345 ENSG00000140464 PMC9569554__F2 Hypoxia-Inducible Factors Signaling in Osteogenesis and Skeletal Repair ENSG00000125398 ENSG00000149968 ENSG00000128917 ENSG00000288335 ENSG00000100985 ENSG00000118257 ENSG00000073756 ENSG00000007171 ENSG00000158859 PMC6367275__F2 Schematic and simplified representation of the several components of the IGF-1/PI3K/AKT/mTOR pathway discussed in this review ENSG00000002330 ENSG00000155792 ENSG00000140443 PMC7536068__F1 Schematic depicting an overview of the autophagy pathway and mechanisms used to manipulate autophagy ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC5928262__F1 Ang/Tie pathway regulation of vascular stability ENSG00000144935 ENSG00000291971 ENSG00000150907 ENSG00000163914 ENSG00000065802 PMC2735125__F7 HP1 Proteins Form Distinct Complexes and Mediate Heterochromatic Gene Silencing by Non-Overlapping Mechanisms ENSG00000166869 ENSG00000187446 ENSG00000138433 ENSG00000092847 PMC2408433__F1 Glucose transport regulation by the Akt/TSC pathway ENSG00000198793 PMC7283559__F1 C-type lectin receptor signaling in TB and HIV ENSG00000260314 ENSG00000134982 ENSG00000172936 PMC7112240__F1 Drosophila-associated bacteria differentially shape the nutritional requirements of their host during juvenile growth ENSG00000110711 PMC8699653__F2 Methylation Markers in Cutaneous Melanoma: Unravelling the Potential Utility of Their Tracking by Liquid Biopsy ENSG00000149311 ENSG00000175054 ENSG00000002330 ENSG00000170430 PMC3909204__F1 EGFR and FGFR Pathways Have Distinct Roles in Drosophila Mushroom Body Development and Ethanol-Induced Behavior ENSG00000163914 ENSG00000146648 PMC8446437__F2 Targeting Indoleamine 2,3-Dioxygenase 1: Fighting Cancers via Dormancy Regulation ENSG00000111537 ENSG00000106546 PMC8222670__F4 Inflammatory Profile of the Tumor Microenvironment, Orchestrated by Cyclooxygenase-2, Promotes Epithelial-Mesenchymal Transition ENSG00000169554 ENSG00000138798 ENSG00000168036 PMC4820400__F2 Amyloid-Beta Protein Clearance and Degradation (ABCD) Pathways and their Role in Alzheimer’s Disease ENSG00000100985 ENSG00000119912 PMC4275944__F5 A schematic linking the nucleotide binding and oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome activation to status epilepticus (SE) pathogenesis ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC6412771__F2 De novo synthesis of NAD(P) from tryptophan, nicotinamide and nicotinic acid ENSG00000105835 ENSG00000172890 ENSG00000183077 PMC7022881__F1 Two signaling pathways that respond to extracellular glucose in Saccharomyces cerevisiae ENSG00000196511 ENSG00000117228 PMC6279876__F4 Schematic model of HPV-driven carcinogenesis ENSG00000112242 ENSG00000135446 ENSG00000105810 ENSG00000096717 PMC9634088__F2 Immune defenses of the mammary gland epithelium of dairy ruminants ENSG00000174125 ENSG00000135218 ENSG00000167207 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000106100 ENSG00000164342 PMC6557761__F5 Evaluations on Substrates of FBXL Family E3s(A and B) Known (red edge) and predicted (gray edge) ESIs for FBXLs ENSG00000174989 ENSG00000108654 ENSG00000205250 ENSG00000076003 ENSG00000124762 ENSG00000141232 ENSG00000103479 ENSG00000053501 ENSG00000105325 ENSG00000079246 ENSG00000198742 ENSG00000104320 ENSG00000077312 ENSG00000135722 ENSG00000285442 ENSG00000284832 ENSG00000165119 ENSG00000125651 ENSG00000276833 ENSG00000125870 ENSG00000068028 ENSG00000114126 ENSG00000147669 ENSG00000167986 ENSG00000136848 ENSG00000127452 ENSG00000077152 ENSG00000221914 ENSG00000167005 ENSG00000005812 ENSG00000110651 ENSG00000168036 ENSG00000101266 ENSG00000145386 ENSG00000164305 ENSG00000114738 ENSG00000168003 ENSG00000153767 ENSG00000107872 ENSG00000123374 ENSG00000005339 ENSG00000100906 ENSG00000133835 ENSG00000033800 ENSG00000126883 ENSG00000126749 ENSG00000175029 ENSG00000072803 ENSG00000077232 ENSG00000273772 ENSG00000067606 ENSG00000145743 ENSG00000132341 PMC10302777__F2 Betaine as a Functional Ingredient: Metabolism, Health-Promoting Attributes, Food Sources, Applications and Analysis Methods PMC3747540__F1 Emerging signaling pathways in hepatocellular carcinoma ENSG00000186575 ENSG00000164161 ENSG00000136869 ENSG00000150457 ENSG00000128602 ENSG00000131023 ENSG00000189079 PMC6627996__F3 TLR4 signal pathway in oxidative stress ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC3434202__F1 Suppression of Cancer Progression by MGAT1 shRNA Knockdown ENSG00000131446 ENSG00000168282 ENSG00000152127 PMC6627996__F2 TLR2 signal pathway involved in oxidative stress ENSG00000172936 ENSG00000150455 PMC3185699__F1 Proposed signaling pathway to the actin cytoskeleton during HIV-1 entry in T lymphocytes ENSG00000094631 ENSG00000113263 ENSG00000121966 PMC6109047__F7 Pictorial Abstract ENSG00000004975 ENSG00000087245 ENSG00000168036 ENSG00000100985 PMC5142237__F1 The canonical and noncanonical pathways by which the NACHT, LRR, and PYD domains-containing protein 3 (NLRP3) inflammasome is activated and elicits an inflammatory response ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC5470118__F3 Canonical cannabinoid receptor (CBR)-mediated, G protein-dependent signaling pathways ENSG00000291971 ENSG00000198793 ENSG00000168610 PMC5144105__F2 Signal transduction pathways in cranial development ENSG00000105722 ENSG00000154342 ENSG00000281324 ENSG00000140262 ENSG00000162337 ENSG00000120149 ENSG00000168036 ENSG00000277641 ENSG00000066468 ENSG00000170365 ENSG00000122691 ENSG00000165879 ENSG00000077782 PMC9293517__F10 Explore the Therapeutic Composition and Mechanism of Schisandra chinensis-Acorus tatarinowii Schott on Alzheimer's Disease by Using an Integrated Approach on Chemical Profile, Network Pharmacology, and UPLC-QTOF/MS-Based Metabolomics Analysis ENSG00000173599 PMC3004331__F3 Differential host transcriptional responses within the acute-phase response pathway in r1918-infected WT, TNFRKO, and IL1RKO mice at 1, 3, and 5 dpi ENSG00000110799 ENSG00000102871 ENSG00000198793 ENSG00000105697 ENSG00000130159 ENSG00000166278 ENSG00000168610 ENSG00000180210 ENSG00000196136 ENSG00000113905 ENSG00000145192 ENSG00000172936 ENSG00000175104 ENSG00000171560 PMC3541025__F1 Autoinflammatory Disease Reloaded: A Clinical Perspective ENSG00000162711 ENSG00000140368 ENSG00000115594 PMC10540234__F8 Sulforaphane and bladder cancer: a potential novel antitumor compound ENSG00000104856 ENSG00000111321 PMC6059697__F11 p53 signaling pathway obtained from the DAVID Database ENSG00000149311 ENSG00000175054 ENSG00000136997 ENSG00000112378 ENSG00000196470 ENSG00000026103 PMC3293632__F1 Control of the EGFR pathway and cell cycle entry by miRNAs ENSG00000115415 ENSG00000168610 ENSG00000146648 ENSG00000139687 PMC9372658__F1 TAK-242 ameliorates epileptic symptoms in mice by inhibiting the TLR4/NFKB signaling pathway ENSG00000015285 ENSG00000136869 PMC8231946__F2A Proliferation, dissemination and proteasome inhibitor resistance ENSG00000109321 ENSG00000121966 PMC7697684__F3 New Twist in Protein Kinase B/Akt Signaling: Role of Altered Cancer Cell Metabolism in Akt-Mediated Therapy Resistance ENSG00000128050 ENSG00000008130 ENSG00000102967 ENSG00000159399 ENSG00000084774 PMC4974115__F1 Complement in disease: a defence system turning offensive ENSG00000177455 ENSG00000186716 ENSG00000203710 ENSG00000197405 ENSG00000196352 ENSG00000110651 ENSG00000117335 ENSG00000120885 ENSG00000163661 ENSG00000117322 ENSG00000182326 ENSG00000236625 PMC7697684__F5 Major steps of glycolysis and direct and indirect regulation of glycolytic enzymes (in light blue) via Akt ENSG00000074800 ENSG00000008130 ENSG00000169299 ENSG00000159399 PMC4057522__F8 Possible mechanism implicated in tamoxifen resistance in the TAMR cell line model ENSG00000125398 ENSG00000143842 ENSG00000124766 ENSG00000134595 PMC9461661__F4 Targeting Ferroptosis by Ubiquitin System Enzymes: A Potential Therapeutic Strategy in Cancer ENSG00000118369 ENSG00000135655 ENSG00000163930 ENSG00000151012 ENSG00000102226 ENSG00000100387 ENSG00000167468 ENSG00000111684 ENSG00000116750 ENSG00000155313 ENSG00000101557 ENSG00000079999 PMC9495541__F6 Cynanoside F Controls Skin Inflammation by Suppressing Mitogen-Activated Protein Kinase Activation ENSG00000125538 ENSG00000203782 ENSG00000145777 PMC8634166__F8 Uncovering Bupi Yishen Formula Pharmacological Mechanisms Against Chronic Kidney Disease by Network Pharmacology and Experimental Validation ENSG00000172936 ENSG00000136869 ENSG00000159399 PMC9461661__F3 Targeting Ferroptosis by Ubiquitin System Enzymes: A Potential Therapeutic Strategy in Cancer ENSG00000132109 ENSG00000078668 ENSG00000291729 ENSG00000124702 ENSG00000079999 ENSG00000145604 ENSG00000069869 ENSG00000163462 ENSG00000197530 ENSG00000100387 ENSG00000167468 ENSG00000111684 ENSG00000123983 PMC4383535__F3 Genome Sequencing of the Perciform Fish Larimichthys crocea Provides Insights into Molecular and Genetic Mechanisms of Stress Adaptation ENSG00000148926 ENSG00000170893 PMC3077649__F7 Model of Egr-1/GGPPS/Erk1/2 pathway regulating insulin resistance in hyperinsulinism ENSG00000169291 ENSG00000115904 PMC8209548__F8 Periostin/Filamin-A: A Candidate Central Regulatory Axis for Valve Fibrogenesis and Matrix Compaction ENSG00000070831 ENSG00000149269 PMC4197584__F7 Pathway interactions regulating midgut patterning ENSG00000160973 ENSG00000164736 ENSG00000156574 PMC3476735__F5 Metformin, an anti-diabetic agent reduces growth of cutaneous squamous cell carcinoma by targeting mTOR signaling pathway ENSG00000117020 ENSG00000169047 PMC8034938__F7 Celecoxib attenuated ZD-promoted tumorigenesis through suppressing inflammations ENSG00000124102 ENSG00000081041 ENSG00000168036 PMC7906116__F8 Interplay and roles of oxidative stress, toll-like receptor 4 and Nrf2 in trichloroethene-mediated autoimmunity ENSG00000175793 ENSG00000172936 ENSG00000136869 PMC6306737__F1 Metabolic pathway of lipid metabolism in muscle ENSG00000157184 ENSG00000136457 ENSG00000166278 ENSG00000177646 PMC3945337__F1 Quantifying the Sources of the Essential Sugar Mannose♦ PMC3871247__F6 TTC7A mutations disrupt intestinal epithelial apicobasal polarity ENSG00000163914 PMC8965480__F9 Disease-associated microglial activation prevents photoreceptor degeneration by suppressing the accumulation of cell debris and neutrophils in degenerating rat retinas ENSG00000182578 ENSG00000167601 ENSG00000129226 PMC4214092__F1 Senescent cells in ageing ENSG00000149311 ENSG00000175054 ENSG00000172840 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC5103168__F6 Pre‐ and Post‐Natal Stress Programming: Developmental Exposure to Glucocorticoids Causes Long‐Term Brain‐Region Specific Changes to Transcriptome in the Precocial Japanese Quail ENSG00000100234 ENSG00000136011 ENSG00000169688 ENSG00000115353 ENSG00000157445 ENSG00000204941 PMC7242738__F3 KEGG pathway for TNFA (bta04668) with the annotated DEGs in our results between Besnoitia besnoiti-infected BAEC cells at 32 hpi vs ENSG00000177606 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000062485 PMC7697684__F8 New Twist in Protein Kinase B/Akt Signaling: Role of Altered Cancer Cell Metabolism in Akt-Mediated Therapy Resistance ENSG00000143799 ENSG00000149311 ENSG00000131473 ENSG00000012048 ENSG00000175054 ENSG00000073614 ENSG00000291803 ENSG00000051180 ENSG00000108106 ENSG00000101557 PMC7697684__F7 Fatty acid synthesis and Akt-mediated regulation of lipid metabolism via phosphorylation of its targets and SREBP-dependent expression of various proteins (in light blue) ENSG00000131473 ENSG00000130164 ENSG00000026103 PMC7472444__F6 Whole-transcriptome Analysis of Fully Viable Energy Efficient Glycolytic-null Cancer Cells Established by Double Genetic Knockout of Lactate Dehydrogenase A/B or Glucose-6-Phosphate Isomerase ENSG00000109819 ENSG00000254550 PMC7472444__F5 Whole-transcriptome Analysis of Fully Viable Energy Efficient Glycolytic-null Cancer Cells Established by Double Genetic Knockout of Lactate Dehydrogenase A/B or Glucose-6-Phosphate Isomerase ENSG00000081181 ENSG00000124253 ENSG00000116761 PMC7472444__F4 Whole-transcriptome Analysis of Fully Viable Energy Efficient Glycolytic-null Cancer Cells Established by Double Genetic Knockout of Lactate Dehydrogenase A/B or Glucose-6-Phosphate Isomerase ENSG00000067057 ENSG00000124253 ENSG00000159399 PMC7377904__F2 Activation of the Wnt canonical pathway induces Beta-catenin-regulated gene expression ENSG00000134982 PMC7372973__F3 JAK-STAT signaling pathway ENSG00000138378 ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000105639 ENSG00000168610 PMC2707271__F5 Proposed mechanism for MAP4K3 cell death signaling ENSG00000011566 ENSG00000002330 PMC7377904__F3 Vitamin D interferes with Beta-catenin induced gene expression via different pathways in different cell types ENSG00000162337 ENSG00000168036 PMC5070418__F1 Signaling pathway involving mTORC1 ENSG00000177169 ENSG00000196712 PMC8790935__F2 NLRP3 Inflammasome in Myocardial Ischemia-Reperfusion Injury and Ventricular Remodeling ENSG00000162711 ENSG00000156026 ENSG00000265972 PMC3823708__F9 NFKB-Induced IL-6 Ensures STAT3 Activation and Tumor Aggressiveness in Glioblastoma ENSG00000128342 ENSG00000168610 PMC7676916__F10 MiR-204-mediated regulatory mechanism in chicken granulosa cell (GC) proliferation, apoptosis, and autophagy ENSG00000177169 ENSG00000198793 ENSG00000141568 PMC10748092__F2 Colorectal Cancer Stem Cells and Targeted Agents ENSG00000119888 ENSG00000198793 ENSG00000272398 ENSG00000026508 ENSG00000168036 ENSG00000128602 ENSG00000168610 PMC6890721__F4 Caffeine, theanine and catechin biosynthetic pathways in plants, and expression patterns of genes related to quality metabolites in ‘Xiaoxueya’ leaves ENSG00000180210 ENSG00000186063 ENSG00000145321 ENSG00000062485 ENSG00000158125 PMC9284495__F7 Bone marrow mesenchymal stem cells facilitate diabetic wound healing through the restoration of epidermal cell autophagy via the HIF-1A/TGFB1/SMAD pathway PMC7368941__F6 Function of podocyte injury is closely related to morphological changes ENSG00000177169 ENSG00000083290 ENSG00000198793 ENSG00000096717 PMC3652647__F7 Schematic model of probable pathway of refractoriness of interferonB signal ENSG00000183735 ENSG00000106100 PMC3580164__F3 Transcriptional integration of mitochondrial biogenesis ENSG00000100811 ENSG00000177169 ENSG00000096717 ENSG00000142082 PMC9036358__F1 Cyclic GMP and PKG Signaling in Heart Failure ENSG00000096088 ENSG00000214285 ENSG00000117152 ENSG00000116741 ENSG00000137672 ENSG00000198626 PMC11853349__F7 Protective mechanism of dapagliflozin in sepsis-induced cardiomyopathy: The SIC model was established by animal experiments ENSG00000170325 ENSG00000168610 PMC6985539__F1 Targeting molecules common to pathways promoting angiogenesis and neuroendocrine phenotype in prostate cancer ENSG00000119547 ENSG00000196591 ENSG00000087586 ENSG00000139687 PMC5606335__F6 Oxygen-dependent regulation of antioxidant production by HIF1 ENSG00000284320 ENSG00000065911 ENSG00000100714 ENSG00000092621 ENSG00000135069 ENSG00000146733 ENSG00000120254 PMC10815547__F8 Scheme of the ginsenoside biosynthetic pathway in ginseng according to Li et al ENSG00000110921 ENSG00000214513 ENSG00000088926 ENSG00000157005 PMC6710771__F1 Ang/Tie2 signalling in the diabetic eye, including crosstalk with the VEGF pathway ENSG00000197713 ENSG00000291971 ENSG00000168036 ENSG00000171791 PMC7072244__F2 ALK-EGFR-AKT pathway promote STING-dependent innate immune response in macrophage during bacterial sepsis ENSG00000183735 ENSG00000164430 ENSG00000146648 PMC2690586__F1 Maintenance of the G1/S DNA damage checkpoint in the presence and absence of Cdk2 ENSG00000149311 ENSG00000175054 ENSG00000123374 PMC8703190__F1 Contribution of Smoothened Receptor Signaling in GABAergic Neurotransmission and Chloride Homeostasis in the Developing Rodent Brain ENSG00000164690 ENSG00000128602 ENSG00000281857 PMC6757314__F3 KEGG pathway analysis of the differentially expressed genes in head and neck squamous cell carcinoma ENSG00000214456 ENSG00000058085 ENSG00000130649 ENSG00000165269 ENSG00000106688 ENSG00000196739 ENSG00000138356 ENSG00000101680 ENSG00000188153 ENSG00000204262 ENSG00000053747 ENSG00000136457 ENSG00000169436 ENSG00000029559 ENSG00000167676 ENSG00000108821 ENSG00000197467 ENSG00000248144 ENSG00000008394 ENSG00000197565 ENSG00000134871 ENSG00000101892 ENSG00000132170 ENSG00000139219 ENSG00000118785 ENSG00000111799 ENSG00000291748 ENSG00000122121 ENSG00000124253 PMC5900771__F1 Methylation and glycerolipid metabolism in yeast ENSG00000042832 ENSG00000173599 ENSG00000026103 PMC8703190__F2 Contribution of Smoothened Receptor Signaling in GABAergic Neurotransmission and Chloride Homeostasis in the Developing Rodent Brain ENSG00000128602 ENSG00000281857 PMC6566801__F2 Possible mechanisms releasing mitochondrial components into the circulation ENSG00000162711 ENSG00000150782 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000158828 PMC5388800__F1 Rheumatoid Arthritis, Immunosenescence and the Hallmarks of Aging ENSG00000111537 ENSG00000174059 ENSG00000104081 ENSG00000026103 PMC7778590__F5 Targeting YAP for PDAC therapy ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC11674716__F7 KEGG network diagram of the adipocytokine signaling pathway ENSG00000102871 ENSG00000198793 ENSG00000115138 ENSG00000127191 ENSG00000168610 PMC7778590__F1 Core components of the Hippo pathway in mammalian cells ENSG00000186575 ENSG00000144560 ENSG00000150457 ENSG00000131023 PMC8144525__F8 Tibetan Medicine Duoxuekang Capsule Ameliorates High-Altitude Polycythemia Accompanied by Brain Injury PMC9419985__F3 Hematopoietic Stem Cells in Wound Healing Response ENSG00000162676 ENSG00000172936 ENSG00000136869 PMC9419985__F2 Hematopoietic Stem Cells in Wound Healing Response ENSG00000291971 ENSG00000172936 ENSG00000136869 PMC4909440__F1 Mechanistic consequences of PREX2 truncating mutations ENSG00000129757 ENSG00000046889 PMC9395635__F1 Road testing new CAR design strategies in multiple myeloma ENSG00000100385 ENSG00000174059 PMC7241259__F2 Wnt pathways ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000168036 PMC8550922__AF1 Protective Role of microRNA-31 in Acetaminophen-Induced Liver Injury: A Negative Regulator of c-Jun N-Terminal Kinase (JNK) Signaling Pathway ENSG00000151657 ENSG00000070831 ENSG00000130649 ENSG00000123908 PMC7037240__F1 GM-CSF–IRF4–CCL17 pathway in inflammation and pain ENSG00000102970 ENSG00000137265 PMC7709111__F5 Three top-scoring interaction networks of highly abundant aqueous humor proteins ENSG00000142798 ENSG00000110244 ENSG00000134982 ENSG00000055955 ENSG00000236625 ENSG00000274619 ENSG00000182667 ENSG00000087245 ENSG00000113889 ENSG00000188770 ENSG00000262655 ENSG00000142192 ENSG00000106333 ENSG00000113600 ENSG00000171403 ENSG00000189056 ENSG00000163453 ENSG00000166278 ENSG00000173402 ENSG00000079557 ENSG00000157131 ENSG00000138207 ENSG00000113905 ENSG00000118785 ENSG00000145192 ENSG00000175899 ENSG00000128564 ENSG00000276838 ENSG00000115461 ENSG00000265203 ENSG00000188783 ENSG00000169814 ENSG00000186395 ENSG00000228278 ENSG00000167768 ENSG00000104112 ENSG00000197746 ENSG00000244731 ENSG00000122194 ENSG00000229314 ENSG00000163815 ENSG00000106927 ENSG00000180210 ENSG00000172260 ENSG00000150991 ENSG00000121410 ENSG00000226492 ENSG00000115457 ENSG00000167779 ENSG00000188157 ENSG00000119655 ENSG00000158874 ENSG00000171951 ENSG00000171560 ENSG00000089199 ENSG00000172867 ENSG00000148346 ENSG00000039537 ENSG00000189058 ENSG00000113140 ENSG00000151655 ENSG00000000971 ENSG00000281123 ENSG00000273686 ENSG00000176919 ENSG00000211445 ENSG00000005421 ENSG00000117601 ENSG00000145321 ENSG00000148702 ENSG00000198734 PMC5549331__F1 Molecular pathways of macrophage polarization ENSG00000169245 ENSG00000260314 ENSG00000115415 ENSG00000137265 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC6070815__F5 Pathways of the annotated DE genes and lincRNAs in the adipose tissues of high- and low-FE pigs ENSG00000005471 ENSG00000119508 ENSG00000157087 ENSG00000173208 ENSG00000079435 ENSG00000087460 PMC11906677__F7 Mechanism of PP suppressing NLRP3 inflammasome by targeting CK1A–Beta-catenin–NFKB–NRF2–mitochondrial OXPHOS pathways during bacterial infection ENSG00000278718 ENSG00000162711 ENSG00000168036 PMC4178922__F2 Fgf7 and Fgf10 signaling via Fgfr2b controls proliferation versus chemotaxis, respectively ENSG00000070193 ENSG00000130147 ENSG00000140285 PMC4017039__F1 Intracellular signal propagation of human toll-like receptors and corresponding ligands in innate immunity ENSG00000174125 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC5949531__F2 Nerve growth factor (NGF) signaling cascade ENSG00000169291 ENSG00000175104 PMC2638772__F9 Model whereby increased Fgfr3 signaling in chondrocytes causes premature synchondrosis closure and unification of ossification centers PMC2869094__F1 Epigenetic regulation of WNT signaling in chronic lymphocytic leukemia ENSG00000004975 ENSG00000112576 ENSG00000107404 ENSG00000138795 ENSG00000156076 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000175592 ENSG00000168036 ENSG00000118971 ENSG00000065717 ENSG00000078747 ENSG00000177606 ENSG00000136997 PMC3788328__F1 Calcium and calcium-permeable channels in the control of autophagy ENSG00000187688 ENSG00000156026 ENSG00000198793 ENSG00000165125 ENSG00000274348 ENSG00000196689 PMC4496399__F6 NGF-induced TrkA/CD44 association is involved in tumor aggressiveness and resistance to lestaurtinib ENSG00000026508 PMC5841365__F2 Macroautophagy: an overview of the molecular pathway and mutations associated with congenital disorders of autophagy ENSG00000135317 ENSG00000292221 ENSG00000177169 ENSG00000152348 ENSG00000126775 ENSG00000104133 ENSG00000144848 ENSG00000141458 ENSG00000145782 ENSG00000057663 PMC7904579__F7 Applying Genome-wide CRISPR to Identify Known and Novel Genes and Pathways that Modulate Formaldehyde Toxicity ENSG00000145604 ENSG00000101407 ENSG00000168003 ENSG00000162337 ENSG00000116586 ENSG00000198793 ENSG00000155792 ENSG00000109270 ENSG00000155876 ENSG00000149357 ENSG00000176641 ENSG00000285069 PMC3940969__F1 Cytokine signaling pathways in brain preconditioning ENSG00000108691 ENSG00000102871 ENSG00000172936 ENSG00000121807 ENSG00000175104 ENSG00000127191 PMC7206068__F5 TRIM proteins in autophagy: selective sensors in cell damage and innate immune responses ENSG00000132109 ENSG00000106785 ENSG00000112343 ENSG00000113595 ENSG00000119401 ENSG00000150455 ENSG00000101557 ENSG00000183735 ENSG00000111537 ENSG00000164430 ENSG00000136869 ENSG00000172936 ENSG00000164342 PMC7206068__F3 TRIM proteins in autophagy: selective sensors in cell damage and innate immune responses ENSG00000177169 ENSG00000132109 ENSG00000110497 ENSG00000108395 ENSG00000213186 ENSG00000123395 ENSG00000168930 ENSG00000119401 ENSG00000112561 ENSG00000121236 ENSG00000141569 ENSG00000111537 ENSG00000175104 ENSG00000221926 ENSG00000130726 PMC9710844__F7 Graphical abstract of DDOST-regulated MITA-mediated signaling pathway ENSG00000183735 ENSG00000164430 PMC5556685__F2 Working model illustrating the potential impact of milk exosome-derived miRNAs on the expression of p53 ENSG00000150907 ENSG00000140443 PMC8005985__F5 Regulatory function of main lncRNAs related to cardiomyocyte maturation ENSG00000182809 ENSG00000215021 ENSG00000276644 ENSG00000112118 ENSG00000214253 PMC8005985__F4 Regulatory effect of H19-LncRNA in cardiomyocyte maturation ENSG00000088992 ENSG00000110693 PMC316782__F1 Genetic pathways of sex determination in D PMC2664743__F4 Calmodulin-Kinases: Modulators of Neuronal Development and Plasticity PMC8294626__F8 H+-ATPase (V-ATPase): from proton pump to signaling complex in health and disease ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000182220 ENSG00000168646 ENSG00000164778 PMC7399735__F6 Gene-to-gene network of Col-0 vs ENSG00000161634 ENSG00000092847 ENSG00000134287 ENSG00000123908 PMC6701373__F2 Transforming growth factor-Beta- (TGF-Beta-) induced EndoMT ENSG00000135446 ENSG00000198793 PMC4033420__F1 Colorectal cancer MSI and CIN signaling pathways modified from KEGG database ENSG00000132906 ENSG00000134982 ENSG00000168036 ENSG00000171791 ENSG00000164305 PMC3571329__F7 Proposed metabolic model for syntrophic growth of D ENSG00000127948 PMC7151181__F3 Signal transduction pathways activated by GlcNAc ENSG00000196511 ENSG00000135605 PMC12196518__F1 Mechanisms of LSEC defenestration and the role of defenestrated LSEC in liver fibrosis ENSG00000163914 ENSG00000127528 ENSG00000101346 ENSG00000198670 ENSG00000162692 ENSG00000168610 PMC4324503__F5 Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation ENSG00000136869 ENSG00000001626 PMC11312279__F9 Ceramide Ehux-C22 Targets the miR-199a-3p/mTOR Signaling Pathway to Regulate Melanosomal Autophagy in Mouse B16 Cells ENSG00000177169 ENSG00000198793 ENSG00000057663 PMC8276988__F2 Immunogenic Cell Death: A Step Ahead of Autophagy in Cancer Therapy ENSG00000110218 ENSG00000145782 ENSG00000057663 ENSG00000292366 PMC5131917__F8 PCNA-Dependent Cleavage and Degradation of SDE2 Regulates Response to Replication Stress ENSG00000132646 ENSG00000143751 ENSG00000070950 PMC12209307__F9 Diagram of the mechanisms by which tricin fighting against KRAS-mutant NSCLC ENSG00000125740 ENSG00000111537 ENSG00000291971 PMC9588367__F8 Identifying and Targeting Prediction of the PI3K-AKT Signaling Pathway in Drug-Induced Thrombocytopenia in Infected Patients Receiving Linezolid Therapy: A Network Pharmacology-Based Analysis ENSG00000157404 ENSG00000188822 ENSG00000198793 ENSG00000087085 ENSG00000089041 ENSG00000087586 ENSG00000163736 ENSG00000007908 ENSG00000121879 ENSG00000104368 ENSG00000163631 ENSG00000126218 ENSG00000138744 ENSG00000108691 ENSG00000128052 ENSG00000123374 ENSG00000275565 ENSG00000146648 PMC9288447__F1 Restored oligodendrogenesis by fibroblast growth factor 17: molecular mechanism for rejuvenating ageing-related memory deficit PMC9588367__F5 Identifying and Targeting Prediction of the PI3K-AKT Signaling Pathway in Drug-Induced Thrombocytopenia in Infected Patients Receiving Linezolid Therapy: A Network Pharmacology-Based Analysis ENSG00000162711 ENSG00000157404 ENSG00000291603 ENSG00000198793 ENSG00000087085 ENSG00000087586 ENSG00000121879 ENSG00000104368 ENSG00000163631 ENSG00000126218 ENSG00000122025 ENSG00000277571 ENSG00000138744 ENSG00000165841 ENSG00000128052 ENSG00000123374 ENSG00000051180 ENSG00000188822 ENSG00000089041 ENSG00000163736 ENSG00000007908 ENSG00000168610 ENSG00000048392 ENSG00000108691 ENSG00000111537 ENSG00000135446 ENSG00000198734 ENSG00000171608 ENSG00000146648 PMC5413598__F1 Hippo signaling pathway ENSG00000186575 ENSG00000144560 ENSG00000150457 ENSG00000131023 PMC4092141__F1 cGMP and NHR Signaling Co-regulate Expression of Insulin-Like Peptides and Developmental Activation of Infective Larvae in Strongyloides stercoralis ENSG00000124102 ENSG00000157933 PMC7686857__F1 Mitochondrial iron co-factor biosynthetic pathways are reliant on FXN iron chaperone function ENSG00000066926 ENSG00000136003 PMC4705527__F5 Deciphering the streamlined genome of Streptomyces xiamenensis 318 as the producer of the anti-fibrotic drug candidate xiamenmycin ENSG00000122966 ENSG00000172005 ENSG00000197429 PMC5964135__F2 Proposed signaling cascades recruited in the setting of remote ischemic conditioning based on available data ENSG00000002330 PMC3039924__F1 Insulin-like growth factor receptor 1 (IGF1R) signaling pathway and potential mechanisms of resistance to IGF1R blockade (red asterisks) ENSG00000171105 ENSG00000002330 ENSG00000197081 ENSG00000169047 ENSG00000198793 ENSG00000164327 ENSG00000146648 PMC9616789__F10A Spatial Analysis of Neural Cell Proteomic Profiles Following Ischemic Stroke in Mice Using High-Plex Digital Spatial Profiling ENSG00000142192 ENSG00000002330 ENSG00000090402 ENSG00000126775 ENSG00000134982 ENSG00000156026 ENSG00000087085 ENSG00000168040 ENSG00000164305 ENSG00000291983 ENSG00000175054 ENSG00000105664 ENSG00000119912 ENSG00000127948 ENSG00000084774 ENSG00000101425 PMC5868625__F6 Summary of the inhibitory effect of ILQ on PI3K/Akt/mTOR pathway members.Abbreviation: ILQ, isoliquiritigenin ENSG00000198793 ENSG00000168036 PMC9433414__F3 Interaction between the circadian clock and mTOR-related signaling transduction pathways ENSG00000142178 ENSG00000146469 ENSG00000169047 ENSG00000145979 ENSG00000155792 ENSG00000132326 ENSG00000179094 ENSG00000167965 PMC11913671__F2 Inflammatory pathways in glomerular disease ENSG00000094631 ENSG00000167613 ENSG00000162711 ENSG00000138378 ENSG00000115415 ENSG00000168610 ENSG00000179295 PMC5243181__F1 Differential gene expression in PPAR signaling pathway ENSG00000150991 ENSG00000100979 ENSG00000165269 PMC8396474__F1 Redox Signaling and Sarcopenia: Searching for the Primary Suspect ENSG00000117525 ENSG00000150907 ENSG00000198793 ENSG00000096717 ENSG00000142082 PMC8615799__F9 Prognostic Biomarkers of OSBPL Family Genes in Patients with Pancreatic Ductal Adenocarcinoma ENSG00000019991 ENSG00000104140 ENSG00000070831 ENSG00000173599 ENSG00000026508 PMC3722447__F1 Defects within components of the ECM and the TGFB signaling pathway leading to various HCTD PMC4211700__F4 PKCD and θ Possibly Mediate FSH-Induced Mouse Oocyte Maturation via NOX-ROS-TACE Cascade Signaling Pathway ENSG00000109321 ENSG00000146648 PMC2945562__F8 Summary of signaling pathways for cPLA2A activation and eicosanoid production stimulated by engagement of C ENSG00000172936 PMC8616420__F3 Molecular Markers to Predict Prognosis and Treatment Response in Uterine Cervical Cancer ENSG00000198793 ENSG00000173846 ENSG00000168040 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC8616420__F2 Molecular Markers to Predict Prognosis and Treatment Response in Uterine Cervical Cancer ENSG00000149311 ENSG00000051180 ENSG00000139618 PMC2662697__F6 Chlamydia pneumoniae-Induced Foam Cell Formation Requires MyD88 Dependent and Independent Signaling and is Reciprocally Modulated by LXR Activation ENSG00000135218 ENSG00000170458 ENSG00000172936 ENSG00000136869 PMC5585386__F6 Schematic representation of a B ENSG00000173599 ENSG00000285482 ENSG00000198670 ENSG00000062282 PMC6709694__F4 Integration of HTS and CTD informs disease-pathway connections ENSG00000111837 ENSG00000145020 PMC8201405__F4 Herpes Simplex Virus 1 Infection of Neuronal and Non-Neuronal Cells Elicits Specific Innate Immune Responses and Immune Evasion Mechanisms ENSG00000183735 ENSG00000164430 ENSG00000119401 PMC8201405__F3 Herpes Simplex Virus 1 Infection of Neuronal and Non-Neuronal Cells Elicits Specific Innate Immune Responses and Immune Evasion Mechanisms ENSG00000239732 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC3382968__F1 The four principal manifestations of immunological autophagy ENSG00000162711 ENSG00000163568 ENSG00000175104 PMC3460045__F3 Pathological functions of LOX family oxidases during cancer progression and metastasis ENSG00000112715 PMC9011227__F1 Lipid rafts in persistent Helicobacter pylori infection: a narrative review ENSG00000115415 ENSG00000138755 PMC7802409__F3 Microglia damage to neurons after encephalitis leads to neurological complications in survivors ENSG00000111537 ENSG00000181631 PMC12157993__F10 TV-EV-induced inflammatory cascade in host cells ENSG00000162711 ENSG00000163739 ENSG00000056972 ENSG00000231179 ENSG00000164342 PMC10915131__F6 Working model for the role of the mechanistic target of rapamycin complex 1 (mTORC1) and its regulated macroautophagy in the induction of cardiomyocyte necroptosis by large doses of isoproterenol (ISO) ENSG00000137275 ENSG00000112561 ENSG00000168404 ENSG00000285379 PMC4657734__F2 Smad complexes can cooperate with transcription pathways in the control of gene expression in epithelial-mesenchymal transition ENSG00000176692 ENSG00000169554 ENSG00000168214 ENSG00000213658 ENSG00000168036 ENSG00000129514 ENSG00000164690 ENSG00000128602 PMC4657734__F1 TGF-Beta-activated non-Smad pathways in epithelial-mesenchymal transition ENSG00000070831 ENSG00000198742 ENSG00000076604 PMC12090520__F9 Mechanism by which F1929-1458 activates anti-tumor immunity ENSG00000164430 ENSG00000109320 ENSG00000189403 ENSG00000126353 PMC8633599__F2 Molecular basis for IL-31 production and IL-31-mediated itch transmission: from biology to drug development ENSG00000078747 ENSG00000120937 PMC3685413__F2 SF3B1 and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia ENSG00000165934 ENSG00000005339 ENSG00000170458 ENSG00000057468 ENSG00000136997 ENSG00000121067 ENSG00000187741 ENSG00000168036 ENSG00000100888 ENSG00000147082 PMC6131564__F4 Sub-pathway of the HIF-1 signaling pathway identified on the basis of sub-pathway strategy ENSG00000280616 ENSG00000160336 ENSG00000169032 ENSG00000006062 ENSG00000146648 ENSG00000187840 ENSG00000140443 PMC9449579__F3 Targeting the key cholesterol biosynthesis enzyme squalene monooxygenasefor cancer therapy ENSG00000057252 ENSG00000019186 ENSG00000198793 ENSG00000104549 ENSG00000168036 ENSG00000167780 PMC6131564__F3 Sub-pathway of chemokine signaling pathway identified on the basis of sub-pathway strategy ENSG00000129946 ENSG00000172005 ENSG00000169032 ENSG00000069966 PMC8997990__F6 FOXO1 Couples KGF and PI-3K/AKT Signaling to NKX2.1-Regulated Differentiation of Alveolar Epithelial Cells ENSG00000150907 ENSG00000168878 ENSG00000168484 PMC6131564__F2 Sub-pathway of the MAPK signaling pathway identified on the basis of sub-pathway strategy ENSG00000172680 ENSG00000095015 ENSG00000141639 ENSG00000065559 ENSG00000169032 PMC9449579__F1 Targeting the key cholesterol biosynthesis enzyme squalene monooxygenasefor cancer therapy ENSG00000160752 ENSG00000197429 ENSG00000113161 ENSG00000104549 PMC8122029__F7 Transcriptome profiling of insulin sensitive tissues from GH deficient mice following GH treatment ENSG00000213928 ENSG00000179091 PMC9588367__F3 Identifying and Targeting Prediction of the PI3K-AKT Signaling Pathway in Drug-Induced Thrombocytopenia in Infected Patients Receiving Linezolid Therapy: A Network Pharmacology-Based Analysis ENSG00000143799 ENSG00000162711 ENSG00000157404 ENSG00000178999 ENSG00000198793 ENSG00000087085 ENSG00000087586 ENSG00000121879 ENSG00000104368 ENSG00000163631 ENSG00000126218 ENSG00000122025 ENSG00000277571 ENSG00000183735 ENSG00000165841 ENSG00000128052 ENSG00000095303 ENSG00000123374 ENSG00000051180 ENSG00000077782 ENSG00000164344 ENSG00000275565 ENSG00000253729 ENSG00000188822 ENSG00000089041 ENSG00000163736 ENSG00000007908 ENSG00000168610 ENSG00000070756 ENSG00000048392 ENSG00000108691 ENSG00000111537 ENSG00000135446 ENSG00000198734 ENSG00000149554 ENSG00000171608 ENSG00000146648 PMC9588367__F2 Identifying and Targeting Prediction of the PI3K-AKT Signaling Pathway in Drug-Induced Thrombocytopenia in Infected Patients Receiving Linezolid Therapy: A Network Pharmacology-Based Analysis ENSG00000126218 ENSG00000291603 ENSG00000188822 ENSG00000165841 ENSG00000087085 ENSG00000087586 ENSG00000104368 PMC5846366__F2 Molecular targets of natural compounds in breast cancer pathway ENSG00000168040 ENSG00000026103 PMC11735026__SF4_3. GnRH signaling pathway: The KEGG graph shows the involvement of ADCY3 and MMP2 genes driving the GnRH signaling pathway ENSG00000087245 ENSG00000070831 ENSG00000291971 ENSG00000113070 ENSG00000095015 ENSG00000115904 ENSG00000143933 ENSG00000088256 ENSG00000166484 ENSG00000137841 ENSG00000087460 ENSG00000109163 ENSG00000128272 ENSG00000120899 ENSG00000157227 ENSG00000177606 ENSG00000146648 PMC3559784__F5 The Carcinogenic Liver Fluke, Clonorchis sinensis: New Assembly, Reannotation and Analysis of the Genome and Characterization of Tissue Transcriptomes ENSG00000105664 ENSG00000174080 ENSG00000132341 PMC4898879__F7 Melanopsin Regulates Both Sleep-Promoting and Arousal-Promoting Responses to Light ENSG00000122375 PMC7341904__F1 Upregulation of the MAPK pathway in tumor cells leads to proliferation and progression of thyroid cancer ENSG00000157764 ENSG00000198793 ENSG00000180616 PMC8353273__F2 Cytosolic DNA-Sensing cGAS-STING Pathway in Liver Diseases ENSG00000177169 ENSG00000106785 ENSG00000146063 ENSG00000112343 ENSG00000083290 ENSG00000119401 ENSG00000159461 ENSG00000163565 ENSG00000137699 ENSG00000186480 ENSG00000169871 ENSG00000090432 ENSG00000163904 ENSG00000164430 ENSG00000176986 ENSG00000197594 ENSG00000135912 ENSG00000138468 ENSG00000170703 ENSG00000138942 ENSG00000247315 ENSG00000143258 ENSG00000173456 PMC8766746__F5 Robo2 and Gen1 Coregulate Ureteric Budding by Activating the MAPK/ERK Signaling Pathway in Mice ENSG00000178295 ENSG00000145147 ENSG00000244405 ENSG00000185008 PMC3806315__F4 Serine, glycine and the one-carbon cycle: cancer metabolism in full circle ENSG00000092621 ENSG00000123505 ENSG00000178445 PMC8353273__F1 Cytosolic DNA-Sensing cGAS-STING Pathway in Liver Diseases ENSG00000183735 ENSG00000164430 PMC8821531__F6 T Cell Repertoire Abnormality in Immunodeficiency Patients with DNA Repair and Methylation Defects ENSG00000149311 PMC6738402__F1 Role of Fyn in misfolded Alpha-synuclein (ASyn)-mediated NLRP3 inflammasome activation ENSG00000162711 ENSG00000135218 ENSG00000010810 PMC11942496__F3 Function of the MAPK Signaling Pathway in Cardiac Hypertrophy ENSG00000198793 PMC3806315__F2 Serine, glycine and the one-carbon cycle: cancer metabolism in full circle ENSG00000228716 ENSG00000178445 PMC2778737__F4 Nephron development and cell lineages ENSG00000162552 ENSG00000125931 ENSG00000251493 ENSG00000106829 PMC9179380__F2 NOTCH1, GATA3, and c-MYC in T Cell Non-Hodgkin Lymphomas ENSG00000122025 ENSG00000166349 ENSG00000039537 ENSG00000157404 ENSG00000026508 ENSG00000166278 ENSG00000049768 ENSG00000175097 ENSG00000026103 PMC9179380__F1 NOTCH1, GATA3, and c-MYC in T Cell Non-Hodgkin Lymphomas ENSG00000150907 ENSG00000137265 ENSG00000107485 ENSG00000103522 ENSG00000049768 ENSG00000106546 PMC8122951__F2 Bone Marrow Niche in B-Cell Acute Lymphoblastic Leukemia: The Role of Microenvironment from Pre-Leukemia to Overt Leukemia ENSG00000178860 ENSG00000177575 ENSG00000168329 ENSG00000108691 ENSG00000107562 ENSG00000074181 ENSG00000162692 ENSG00000163661 ENSG00000167508 ENSG00000121807 ENSG00000121966 PMC3158866__F1 Toll-like receptor signaling pathway ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC5678904__F3 TGF‐B/SMAD/CTCF signaling pathway ENSG00000102974 PMC2949647__F1 Structure and signaling machinery of the Met receptor ENSG00000070831 PMC10912471__F2 Notch signaling pathway in tumor immune microenvironment PMC10912471__F1 Notch signaling pathway ENSG00000168214 ENSG00000022267 ENSG00000184916 PMC4824345__F7 The GacS/A-RsmA Signal Transduction Pathway Controls the Synthesis of Alkylresorcinol Lipids that Replace Membrane Phospholipids during Encystment of Azotobacter vinelandii SW136 PMC3785008__F1 Role of hypoxia and HIF2A in development of the sympathoadrenal cell lineage and chromaffin cell tumours with distinct catecholamine phenotypic features ENSG00000135547 ENSG00000128917 ENSG00000198793 ENSG00000112715 ENSG00000114315 PMC8659360__F1 Selective Progesterone Receptor Modulators—Mechanisms and Therapeutic Utility ENSG00000138798 ENSG00000125084 PMC5435970__F7 Model depicting the mechanisms by which TIEG1 modulates canonical Wnt pathway activity in osteoblasts ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC9161817__F1 Autophagy and the Bone Marrow Microenvironment: A Review of Protective Factors in the Development and Maintenance of Multiple Myeloma ENSG00000128272 ENSG00000057663 PMC4346003__F5 Gene network, created using IPA® software, reflecting EGCG treatment.Notes: The overexpressed genes are labeled in red, while those downregulated are marked in green.Abbreviations: EGCG, epigallocatechin-3-gallate; IPA, Ingenuity®Pathway Analysis ENSG00000110711 ENSG00000136997 ENSG00000026103 PMC2939633__F1 Chk1 suppressed death pathways ENSG00000149311 ENSG00000175054 ENSG00000093009 PMC8323007__F3 MicroRNA-490-3p and −490-5p in carcinogenesis: Separate or the same goal? ENSG00000281324 ENSG00000162337 ENSG00000107854 ENSG00000198793 ENSG00000165879 ENSG00000168036 ENSG00000118707 ENSG00000185591 ENSG00000112715 ENSG00000121879 ENSG00000168610 ENSG00000146648 PMC3614012__F2 IGF-1R and EGFR/HER2crosstalk occurs by two main mechanisms ENSG00000146648 ENSG00000140443 PMC7792208__F1 Multistep model of the evolution of classic ILC and its morphological variants ENSG00000117713 ENSG00000065361 ENSG00000121879 PMC5751361__F12 TGFB signaling pathway PMC4946436__F8 Interplay between ErbB3 and CXCR4 for the activation of Rac1 and breast cancer cell motility ENSG00000113905 ENSG00000065361 ENSG00000121966 PMC4134798__F1 Mechanism of bone resorption in bone marrow metastasis ENSG00000107562 ENSG00000198670 ENSG00000162692 ENSG00000121966 PMC4669118__F9 Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway ENSG00000131089 ENSG00000070831 ENSG00000140575 PMC4880855__F1 The (simplified) gene regulatory network controlling primary sex determination in placental mammals (see Additional file : Figure S1 for the more complete network) ENSG00000162552 ENSG00000125398 ENSG00000137090 ENSG00000285109 ENSG00000102678 PMC9613846__F3 Transcriptome and Metabolome Analyses Reveals the Pathway and Metabolites of Grain Quality Under Phytochrome B in Rice (Oryza sativa L.) ENSG00000110934 ENSG00000120690 ENSG00000221818 ENSG00000102034 ENSG00000073578 ENSG00000176715 ENSG00000091140 PMC8503804__F2 Circular RNA regulates the onset and progression of cancer through the mitogen-activated protein kinase signaling pathway ENSG00000172936 ENSG00000029993 ENSG00000112715 ENSG00000077782 ENSG00000146648 ENSG00000147689 PMC3322137__F3 Pathway-Based Evaluation in Early Onset Colorectal Cancer Suggests Focal Adhesion and Immunosuppression along with Epithelial-Mesenchymal Transition ENSG00000002330 PMC1464269__F1 Regulation of lactate production at the onset of ischaemia is independent of mitochondrial NADH/NAD+: insights from in silico studies ENSG00000042832 ENSG00000122966 ENSG00000172005 PMC3113646__F6 TGFBeta-and bleomycin-induced extracellular matrix synthesis is mediated through Akt and mammalian target of rapamycin (mTOR) ENSG00000100234 ENSG00000124102 ENSG00000198793 PMC2944409__F7 Gene interaction sub-network of shortest connections to common targets for the 36 candidate regulatory genes obtained by global literature analysis (Pathway Studio 7.0, Ariadne Genomics Inc., Rockville MD) ENSG00000087245 ENSG00000152661 ENSG00000171791 ENSG00000112715 ENSG00000125676 ENSG00000073756 ENSG00000121966 ENSG00000116001 ENSG00000069869 ENSG00000112739 ENSG00000157227 ENSG00000163017 ENSG00000100985 ENSG00000162692 ENSG00000146648 ENSG00000154096 ENSG00000113494 PMC2944409__F6 Calcium Signaling Pathway (KEGG, Kanehisa Laboratory in Kyoto University, Japan) with vinclozolin altered genes indicated ENSG00000156026 ENSG00000186716 PMC3712669__F1 The estrogen metabolic pathway is depicted PMC3708595__F4 Mutational Landscape of Adenoid Cystic Carcinoma ENSG00000073584 ENSG00000083168 ENSG00000147862 ENSG00000196782 ENSG00000181555 ENSG00000132510 ENSG00000117713 ENSG00000012048 ENSG00000136997 ENSG00000174197 ENSG00000253729 ENSG00000109670 ENSG00000005339 ENSG00000120071 ENSG00000085185 ENSG00000027644 ENSG00000110042 ENSG00000276043 ENSG00000151276 ENSG00000149311 ENSG00000214114 ENSG00000183337 ENSG00000160867 ENSG00000054267 ENSG00000080603 ENSG00000185787 ENSG00000198586 PMC5667900__F4 Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway ENSG00000168003 ENSG00000010704 ENSG00000151012 ENSG00000167468 ENSG00000111684 PMC4642978__F2 Differential Gene Expression Profiles and Selected Cytokine Protein Analysis of Mediastinal Lymph Nodes of Horses with Chronic Recurrent Airway Obstruction (RAO) Support an Interleukin-17 Immune Response ENSG00000134339 ENSG00000138207 ENSG00000161798 ENSG00000120693 ENSG00000163661 ENSG00000171560 PMC7685705__F9 The role of TRAF3 in density-dependent proliferation ENSG00000104856 ENSG00000131323 ENSG00000127191 PMC11650353__F7 Proposed model of curcumin inhibiting PCa progression via regulation of m6A-modified circ0030568-FMR1 pathway ENSG00000102081 ENSG00000198492 ENSG00000165819 PMC7411855__F3 MAPK and NFKB signaling pathway of ginkgolides in the regulation of IIR ENSG00000174125 ENSG00000183735 ENSG00000172936 ENSG00000136869 ENSG00000276561 ENSG00000184216 PMC3334999__F5 Unique Combination of Male Germ Cell miRNAs Coordinates Gonocyte Differentiation ENSG00000087095 ENSG00000177732 ENSG00000134982 ENSG00000176887 ENSG00000155011 ENSG00000177606 ENSG00000026508 ENSG00000168036 ENSG00000136044 ENSG00000196628 ENSG00000157240 PMC9448717__F1 Anti-factor H antibody and its role in atypical hemolytic uremic syndrome ENSG00000039537 ENSG00000113600 PMC3334999__F6 Unique Combination of Male Germ Cell miRNAs Coordinates Gonocyte Differentiation ENSG00000107779 ENSG00000002330 ENSG00000110395 ENSG00000112964 ENSG00000081051 ENSG00000146648 PMC9577795__F4 Identification of key genes and pathway related to chemoresistance of small cell lung cancer through an integrative bioinformatics analysis ENSG00000171246 ENSG00000164638 ENSG00000134594 ENSG00000110799 ENSG00000154639 ENSG00000106236 ENSG00000149781 ENSG00000182459 ENSG00000118508 ENSG00000182400 ENSG00000198853 ENSG00000146094 ENSG00000139278 ENSG00000170608 ENSG00000104899 ENSG00000137273 ENSG00000182118 ENSG00000172476 ENSG00000157992 ENSG00000288503 ENSG00000149091 ENSG00000088451 ENSG00000281022 ENSG00000179673 ENSG00000131095 ENSG00000281931 ENSG00000115468 ENSG00000177854 ENSG00000186314 ENSG00000113441 ENSG00000124203 ENSG00000123684 ENSG00000273992 ENSG00000071203 ENSG00000105523 ENSG00000178403 ENSG00000135643 ENSG00000211455 ENSG00000197860 ENSG00000007216 ENSG00000221887 ENSG00000175662 ENSG00000285383 ENSG00000112640 ENSG00000171533 ENSG00000196363 ENSG00000108312 ENSG00000165169 ENSG00000182687 ENSG00000161798 ENSG00000181409 ENSG00000050767 ENSG00000118971 ENSG00000171345 ENSG00000064300 ENSG00000127129 ENSG00000146950 ENSG00000101850 ENSG00000125352 ENSG00000174348 ENSG00000099282 ENSG00000171951 ENSG00000080644 ENSG00000100379 ENSG00000071991 ENSG00000278195 ENSG00000131473 ENSG00000155229 ENSG00000291559 ENSG00000175793 ENSG00000196839 ENSG00000171532 ENSG00000164543 ENSG00000157911 ENSG00000025039 ENSG00000165678 ENSG00000183160 ENSG00000105642 ENSG00000197343 ENSG00000188643 ENSG00000019582 ENSG00000260027 ENSG00000281614 ENSG00000101255 ENSG00000156925 ENSG00000196371 ENSG00000169727 ENSG00000181195 PMC11042021__F8 KEGG pathway diagram for antigen processing and presentation illustrating the central processes involved in antigen processing and presentation, which are essential for immune system function ENSG00000111537 ENSG00000232326 ENSG00000127022 ENSG00000273686 ENSG00000231925 PMC9577795__F3 Identification of key genes and pathway related to chemoresistance of small cell lung cancer through an integrative bioinformatics analysis ENSG00000105894 ENSG00000131473 ENSG00000169105 ENSG00000099985 ENSG00000110799 ENSG00000115415 ENSG00000113140 ENSG00000177606 ENSG00000180616 ENSG00000281022 ENSG00000125084 ENSG00000284984 PMC11042021__F7 KEGG pathway diagram for graft-vs.-host disease depicting the complex interplay of cellular and molecular interactions involved in the pathogenesis of graft-vs.-host disease (GVHD) ENSG00000134982 PMC9600014__F1 Amyloidogenesis and Neurotrophic Dysfunction in Alzheimer’s Disease: Do They have a Common Regulating Pathway? ENSG00000142192 PMC7601265__F7 Illustration of hypothetical antioxidant mechanism for peptide MS15 against oxidative stress ENSG00000178573 ENSG00000079999 PMC6195737__F2 IGF signaling in the placenta ENSG00000171791 PMC1782796__F7 Affinity maturation, a turning point between life and death for germinal centre (GC) B cells: a working hypothesis ENSG00000110934 PMC4268052__F6 Holoprosencephaly: signalling interactions between the brain and the face, the environment and the genes, and the phenotypic variability in animal models and humans ENSG00000170365 ENSG00000144857 ENSG00000156574 ENSG00000164690 ENSG00000128602 PMC4633891__F10 MiR-148a promotes starvation-induced autophagic activity in HSCs, at least in part, through suppressing the Hedgehog signaling pathway ENSG00000180447 ENSG00000128602 PMC1955177__F3 Cell death in the cardiovascular system ENSG00000198793 ENSG00000132478 ENSG00000140443 PMC5895746__F2 Schematic representation summarizing the functional effects of the three regulatory pathways controlled by IL-1B ENSG00000084093 ENSG00000261857 ENSG00000125538 ENSG00000198793 PMC4642978__F1 Differential Gene Expression Profiles and Selected Cytokine Protein Analysis of Mediastinal Lymph Nodes of Horses with Chronic Recurrent Airway Obstruction (RAO) Support an Interleukin-17 Immune Response ENSG00000134339 ENSG00000138207 ENSG00000161798 ENSG00000285433 ENSG00000171560 ENSG00000169575 PMC11574184__F6 KEGG pathway analysis ENSG00000167207 ENSG00000102871 ENSG00000148798 ENSG00000007908 ENSG00000083799 PMC9206341__F8 Near-infrared light reduces Beta-amyloid-stimulated microglial toxicity and enhances survival of neurons: mechanisms of light therapy for Alzheimer’s disease ENSG00000150782 ENSG00000291971 ENSG00000136869 PMC1143566__F4 Schematic diagram for the Wnt signaling pathway ENSG00000070831 ENSG00000100592 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC4271245__F7 Proposed model linking TBX2 and TBX3 to the TGFB1 signaling pathway ENSG00000121068 ENSG00000135111 PMC1143566__F2 A schematic diagram for the hedgehog (HH) signaling pathway ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC6281419__F1 PHIPing along: Evolution of PHIP as a cancer biomarker and a target for therapy ENSG00000169047 ENSG00000146247 ENSG00000137076 ENSG00000140443 PMC9083544__F1 Engineering Yarrowia lipolytica to Produce Itaconic Acid From Waste Cooking Oil ENSG00000122966 ENSG00000157911 ENSG00000084774 PMC10286596__F2 Resveratrol-modulated mitochondrial biogenesis in neurodegenerative diseases ENSG00000105835 ENSG00000150907 ENSG00000164362 ENSG00000096717 ENSG00000089163 PMC10286596__F1 Mitochondrial biogenesis in neurons ENSG00000096717 ENSG00000122033 ENSG00000162851 ENSG00000106459 PMC9563396__F5 Molecular Mechanism of Ferroptosis in Orthopedic Diseases ENSG00000151012 ENSG00000167468 ENSG00000168610 PMC11827847__F10 Hypothesized mechanism by which NRP1 mediates NGF/TrkA pain signaling PMC9604036__F2 Pesticides and Their Impairing Effects on Epithelial Barrier Integrity, Dysbiosis, Disruption of the AhR Signaling Pathway and Development of Immune-Mediated Inflammatory Diseases ENSG00000111537 ENSG00000125538 ENSG00000106546 PMC7959192__F9 Simplified pathway for NAD metabolism ENSG00000105835 ENSG00000278488 PMC2700095__F10 Alternative kinetic model incorporating unknown transcription factor (TFx) activation by Eda/Edar signaling ENSG00000186197 ENSG00000135960 ENSG00000163235 ENSG00000138798 ENSG00000173039 ENSG00000164690 ENSG00000175104 ENSG00000127191 ENSG00000146648 PMC8201398__F2 Bacteriostatic Potential of Melatonin: Therapeutic Standing and Mechanistic Insights ENSG00000162711 ENSG00000115415 ENSG00000136869 ENSG00000049768 ENSG00000293532 PMC6826302__F2 Mechanisms mediated through IGF-1/IGF-1R ENSG00000169047 ENSG00000140443 PMC6826302__F3 Mechanisms mediated through vitamin D ENSG00000138798 ENSG00000113140 ENSG00000168036 ENSG00000115461 PMC8381213__F1 Insight into the emerging role of SARS-CoV-2 nonstructural and accessory proteins in modulation of multiple mechanisms of host innate defense ENSG00000213928 ENSG00000187608 ENSG00000105397 PMC8539140__F3 LncRNAs in the Regulation of Genes and Signaling Pathways through miRNA-Mediated and Other Mechanisms in Clear Cell Renal Cell Carcinoma ENSG00000089685 ENSG00000253352 ENSG00000131023 PMC8281578__F1 Neutrophil extracellular traps in cancer: not only catching microbes ENSG00000136869 ENSG00000005381 PMC8381213__F2 Insight into the emerging role of SARS-CoV-2 nonstructural and accessory proteins in modulation of multiple mechanisms of host innate defense ENSG00000213928 ENSG00000088888 ENSG00000110713 ENSG00000168040 PMC6859340__F7 Mechanism of Cdc42/Wnt/Beta-catenin signaling pathway in ADSC-derived IPCs ENSG00000154342 ENSG00000070831 ENSG00000134982 ENSG00000139515 ENSG00000168036 PMC11688120__F3 Key signaling pathways in the pathogenesis of CCM ENSG00000170458 ENSG00000198742 ENSG00000198793 ENSG00000127528 ENSG00000173706 ENSG00000136869 ENSG00000121879 ENSG00000136826 PMC9009237__F5 “Reframing” dopamine signaling at the intersection of glial networks in the aged Parkinsonian brain as innate Nrf2/Wnt driver: Therapeutical implications ENSG00000291507 ENSG00000079999 PMC239898__F6 Activation of the MAPK signaling pathway by FSH, ATP and GnRH in ovarian cancer ENSG00000109163 PMC6079386__F14 Gga-miR-302b-5p and gga-miR-302-3p miRNAs ENSG00000180210 ENSG00000087095 ENSG00000165891 ENSG00000104447 ENSG00000150457 PMC8656040__F1 Ketone bodies: from enemy to friend and guardian angel ENSG00000275544 ENSG00000117305 PMC9009237__F4 “Reframing” dopamine signaling at the intersection of glial networks in the aged Parkinsonian brain as innate Nrf2/Wnt driver: Therapeutical implications ENSG00000162711 ENSG00000125538 PMC6954292__F1 Androgen metabolism in human prostate ENSG00000086696 ENSG00000151632 ENSG00000203857 PMC11034170__F3 Updated mechanisms of MASLD pathogenesis ENSG00000168003 ENSG00000167468 ENSG00000145020 ENSG00000115107 PMC8761570__F2 Poly (I:C) induces an immune response by macrophages ENSG00000090863 ENSG00000107798 ENSG00000173391 ENSG00000007171 PMC1899986__F8 A model for cyclin E degradation regulated by two E3 ligases ENSG00000100387 ENSG00000113558 ENSG00000123374 ENSG00000099804 PMC139433__F2 Cell cycle arrest by transforming growth factor (TGF)B and their deregulation in cancer ENSG00000135446 ENSG00000123374 PMC4606200__F1 Programmed death-1 causes T cell exhaustion ENSG00000213928 ENSG00000291603 ENSG00000105397 ENSG00000115415 PMC5928215__F1 Protein and cell turnover of the skeletal muscle ENSG00000169047 ENSG00000168610 PMC9541052__F1 Severity and duration of Hypoglycemia affect platelet-derived protein responses in Caucasians ENSG00000110799 ENSG00000102245 ENSG00000088926 ENSG00000163737 ENSG00000122194 PMC3409633__F1 TLR signaling controls transcription and mRNA half-life ENSG00000136869 ENSG00000184216 PMC2725945__F1 Stabilization, degradation, and activation of the Ci/Gli proteins by the Hh signaling pathway ENSG00000121067 ENSG00000128602 PMC2666548__F1 Reactions and proteins of the mitochondrial FAS pathway ENSG00000116353 ENSG00000255154 ENSG00000163684 ENSG00000100294 ENSG00000149313 PMC9009237__F6 “Reframing” dopamine signaling at the intersection of glial networks in the aged Parkinsonian brain as innate Nrf2/Wnt driver: Therapeutical implications ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000149295 PMC4768070__F2 BST‐2 in viral infection: BST‐2 tethers viruses to the cell membrane and to each other (1) and (2) PMC8269449__F1 Pharmacogenomics of Hypersensitivity to Non-steroidal Anti-inflammatory Drugs ENSG00000226275 ENSG00000134982 PMC6447179__F7 Traumatic brain injury induces long-lasting changes in immune and regenerative signaling ENSG00000039537 ENSG00000197721 ENSG00000123843 ENSG00000197405 ENSG00000166278 ENSG00000176919 ENSG00000159189 ENSG00000182326 ENSG00000274619 ENSG00000173369 ENSG00000173372 ENSG00000288512 ENSG00000123838 PMC6447179__F9 Traumatic brain injury induces long-lasting changes in immune and regenerative signaling ENSG00000107562 ENSG00000081041 ENSG00000111341 ENSG00000185187 ENSG00000091879 ENSG00000162772 PMC7042402__F4 Metabolic mechanisms of macrophage polarization ENSG00000131473 ENSG00000162711 PMC8348138__F5 Transcriptome-Based WGCNA Analysis Reveals Regulated Metabolite Fluxes between Floral Color and Scent in Narcissus tazetta Flower ENSG00000197429 ENSG00000166278 ENSG00000127948 PMC3541196__F3 Dysregulation of the cell cycle pathway during tumor progression ENSG00000112576 ENSG00000129355 ENSG00000277273 ENSG00000118971 ENSG00000124762 ENSG00000134480 ENSG00000198176 ENSG00000134057 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000139687 ENSG00000080839 PMC2997006__F1 Tor pathway in the model fungi Saccharomyces cerevisiae and Schizosaccharomyces pombe PMC9545774__F1 Hypoxia in the tumor microenvironment and targeted therapy ENSG00000198793 ENSG00000204520 ENSG00000137845 PMC6703710__F10 Simplified model illustrating PDGFRA functions in elastogenesis ENSG00000163235 ENSG00000138798 PMC6767864__F2 IFN-λ4 Conundrum: When a Good Interferon Goes Bad ENSG00000184979 ENSG00000236637 ENSG00000187608 ENSG00000105397 ENSG00000185436 PMC5805379__F3 Renaissance of complement therapeutics ENSG00000203710 ENSG00000244731 ENSG00000117322 PMC6491460__F2 Modes of MUC1 control of cellular inflammatory signaling pathways ENSG00000162711 ENSG00000088888 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC4859429__F2 Classical and non-classical roles for pre-receptor control of DHT metabolism in prostate cancer progression ENSG00000086696 ENSG00000151632 ENSG00000277893 ENSG00000197888 ENSG00000196620 ENSG00000187134 PMC4683091__F2 Position-dependent regulation of cell fate in the preimplantation embryo: known and hypothetical mechanisms ENSG00000165556 ENSG00000126016 ENSG00000186575 ENSG00000168214 ENSG00000197905 PMC8027073__F8 TREM2 and CSF1R interaction in microglial survival ENSG00000182578 ENSG00000184371 PMC3837458__F1 Triacylglycerol synthesis and acyl-CoA:diacylglycerol acyltransferase (DGAT) enzymes ENSG00000285482 ENSG00000062282 PMC8013721__F1 Summary of radiation-induced oral mucositis pathogenesis ENSG00000149968 ENSG00000125538 PMC5071109__F4 Cell-free Xenopus egg extracts for studying DNA damage response pathways ENSG00000175054 ENSG00000164053 ENSG00000276618 PMC7508719__F4 The KEGG “TGFB Signaling Pathway” showing differentially regulated genes for the Alizarin (+) treatments (TCPS_OS, PCL_NF, PDLLA_NF) ENSG00000049323 ENSG00000105664 ENSG00000186340 ENSG00000134363 ENSG00000125968 ENSG00000137801 PMC10819970__F8 Engineering CXCL12 biomimetic decoy-integrated versatile immunosuppressive nanoparticle (VIN) for the management of overactivated brain immune microenvironment ENSG00000178860 ENSG00000107562 ENSG00000164430 ENSG00000118520 ENSG00000121966 PMC3513983__F3 Major signaling pathways regulating RSV-induced NFKB and IRF activation in airway epithelial cells ENSG00000183735 ENSG00000088888 ENSG00000164342 PMC4609655__F6 MAPK signaling pathway ENSG00000087095 ENSG00000172680 ENSG00000170458 ENSG00000138798 ENSG00000130159 ENSG00000175104 ENSG00000127191 ENSG00000196712 ENSG00000026103 PMC64856__F9 Network of metabolic pathways leading from Suc (orange, top left) to the volatile phenylpropanoids, phenylpropenes, and terpenoids formed in EMX-1 basil peltate glands (outlined with yellow backgrounds) ENSG00000108849 ENSG00000197429 ENSG00000084774 PMC3079294__F5 SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition ENSG00000132646 ENSG00000070950 PMC5561723__F2 To identify coherent networks of genes influenced directly by smoking, we examined the potential interconnections of the 310 genes identified in the genome wide methylation analysis using PPI information in the STRING database ENSG00000151376 ENSG00000141556 ENSG00000291603 ENSG00000172380 ENSG00000157933 ENSG00000108515 ENSG00000111859 ENSG00000116044 ENSG00000274958 ENSG00000171940 ENSG00000070366 ENSG00000141564 ENSG00000139618 ENSG00000038382 ENSG00000157557 ENSG00000183134 ENSG00000112685 ENSG00000006451 ENSG00000026508 ENSG00000165409 ENSG00000107485 ENSG00000169813 ENSG00000162104 PMC6073700__F5 GHR-JAK2-STAT pathway inhibition mediated by PTP-1B, SHP-1, SHP2 and SIRPA1 ENSG00000168610 PMC4547762__F4 Proteomic Analysis of Disease Stratified Human Pancreas Tissue Indicates Unique Signature of Type 1 Diabetes ENSG00000148346 ENSG00000105835 ENSG00000113600 ENSG00000117139 ENSG00000164985 ENSG00000277571 ENSG00000067704 ENSG00000088888 ENSG00000133110 ENSG00000172725 ENSG00000022267 ENSG00000100985 ENSG00000005381 ENSG00000121060 PMC5796892__F11 Schematic representations demonstrating the role LdISP2 in the modulation of host response ENSG00000009724 ENSG00000291559 ENSG00000166278 ENSG00000182326 PMC6073700__F2 The SOCS proteins mechanisms of GHR-JAK2-STAT pathway inhibition ENSG00000120833 ENSG00000168610 PMC6073700__F1 Activation of the growth hormone receptor and its signal transduction ENSG00000122882 ENSG00000168610 PMC8287682__F9 CMTM7 as a novel molecule of ATG14L-Beclin1-VPS34 complex enhances autophagy by Rab5 to regulate tumorigenicity ENSG00000198793 ENSG00000153551 ENSG00000127948 PMC2635020__F1 CATHEPSIN D – MANY FUNCTIONS OF ONE ASPARTIC PROTEASE ENSG00000077150 PMC4322534__F3 Signalling networks in mouse and human iPS cells ENSG00000198793 ENSG00000128342 ENSG00000168610 ENSG00000136826 PMC6405828__F2 TYRO3 signaling pathway ENSG00000092445 PMC4820821__F1 Hh signaling pathway ENSG00000180447 ENSG00000173040 ENSG00000144857 ENSG00000166813 ENSG00000128602 PMC7392229__F6 Effect of compound kushen injection on cancer cells: Integrated identification of candidate molecular mechanisms ENSG00000145604 ENSG00000118007 ENSG00000135446 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000105810 ENSG00000277273 ENSG00000166851 ENSG00000117399 ENSG00000276876 PMC3729906__F1 Molecules examined by immunohistochemistry ENSG00000102145 ENSG00000112576 ENSG00000177971 ENSG00000010810 ENSG00000172005 ENSG00000132478 ENSG00000113263 ENSG00000124181 PMC7874053__F4 Ingenuity Pathway Analysis (IPA) results for candidate genes of LGS or LGS-like epilepsy ENSG00000168807 ENSG00000121207 ENSG00000173575 ENSG00000134215 ENSG00000158458 ENSG00000214285 ENSG00000117152 ENSG00000147854 ENSG00000274286 ENSG00000136859 ENSG00000185313 ENSG00000152684 ENSG00000013306 ENSG00000064989 ENSG00000204634 ENSG00000292254 PMC8480016__F8 Identification of miRNAs-mediated seed and stone-hardening regulatory networks and their signal pathway of GA-induced seedless berries in grapevine (V. vinifera L.) ENSG00000110711 ENSG00000101193 ENSG00000168374 ENSG00000177084 PMC12013426__F2 Mechanisms of gut microbiome delaying cancer progression ENSG00000171476 ENSG00000198793 ENSG00000100985 ENSG00000106100 ENSG00000028137 PMC12013426__F1 Mechanisms of gut microbiome inhibiting the initiation of cancers ENSG00000161921 ENSG00000187554 ENSG00000168036 ENSG00000136869 ENSG00000185591 ENSG00000168811 PMC7754005__F3 Down‐regulated differentially expressed genes participated in PI3K‐Akt signalling pathway. Red: differentially expressed genes down‐regulated; green: PI3K‐Akt signalling pathway gene ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 PMC7663135__F3 Endo-lysosomal system is a complex pathway that is vital to countless processes in the cell, and its dysfunction results in the hallmarks of many diseases ENSG00000102189 ENSG00000112561 ENSG00000047936 PMC7754005__F2 Up‐regulated differentially expressed genes participated in PPAR signalling pathway. Red: up‐regulated differentially expressed genes; green: ppar signalling pathway genes ENSG00000157184 ENSG00000150991 ENSG00000100979 ENSG00000165269 PMC11854358__F11 Hypothesized mechanistic diagrams for the effect of PFESA-BP2 exposure on EGF signaling and JAK/STAT signaling based on previous supportive studies ENSG00000120833 ENSG00000172216 ENSG00000109320 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000146648 ENSG00000196396 ENSG00000160691 PMC3972679__F2 Apoptotic pathways induced in beta cells in type 2 diabetes ENSG00000162711 ENSG00000002330 ENSG00000121351 PMC3972679__F1 The two pathways of apoptosis ENSG00000168040 PMC10616926__F1 Schematic drawing of the major neuroprotective signaling pathways regulated by ghrelin and GHS ENSG00000135218 ENSG00000171791 PMC8257727__F1 Signal transduction cascades mediating cisplatin-induced apoptosis (for details see in the text) ENSG00000149311 ENSG00000175054 ENSG00000128272 ENSG00000123374 ENSG00000162772 PMC8257727__F3 Signal transduction cascades mediating taxane-induced cell death ENSG00000132646 ENSG00000057663 PMC2893101__F3 Apoptosis Signalling network ENSG00000102871 ENSG00000171791 ENSG00000168040 PMC3534691__F8 Neuregulin Facilitates Nerve Regeneration by Speeding Schwann Cell Migration via ErbB2/3-Dependent FAK Pathway ENSG00000065361 ENSG00000291971 PMC5381904__F2 Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability ENSG00000178999 ENSG00000134982 ENSG00000162409 ENSG00000135446 ENSG00000087586 ENSG00000105810 PMC8187289__F1 CRISPR-Cas9 delivery ENSG00000239732 ENSG00000163568 PMC5428490__F2 Transcriptome pattern differs between two oil biosynthesis tissues in oil palm ENSG00000131238 ENSG00000173599 ENSG00000285482 ENSG00000198670 ENSG00000166123 ENSG00000026103 PMC7261837__F8 Anti-inflammatory responses of circumdatin D ENSG00000172936 ENSG00000175104 ENSG00000168610 PMC12188246__F7 Evaluation of the WNT signaling pathway components in an expanded BMP-SOX9-WNT Turing network ENSG00000125398 ENSG00000137573 PMC2312359__F4 Composite list of expressed genes and enriched transcription factors implicates specific regulatory networks ENSG00000135547 ENSG00000001167 ENSG00000165030 ENSG00000130522 ENSG00000122877 ENSG00000140044 ENSG00000205250 ENSG00000197063 ENSG00000112242 ENSG00000077150 ENSG00000119138 ENSG00000178573 ENSG00000136997 ENSG00000185591 ENSG00000291761 ENSG00000203883 ENSG00000095794 ENSG00000282899 ENSG00000178860 ENSG00000084093 ENSG00000288283 ENSG00000005339 ENSG00000129911 ENSG00000071564 ENSG00000183734 ENSG00000114126 ENSG00000156127 ENSG00000177606 ENSG00000066136 ENSG00000114315 ENSG00000123268 PMC5117493__F6 Signaling pathways associated with differentially expressed proteins as identified by Pathway Studio ENSG00000015285 PMC4726722__F2 Nrf2 in the metabolism of rapidly proliferating cells ENSG00000065833 ENSG00000065911 PMC6829482__F7 The role of MyoF during skeletal muscle development ENSG00000122180 ENSG00000134982 ENSG00000168036 ENSG00000138119 PMC3400831__F5 PGI2signaling pathways in VSMCs ENSG00000145604 PMC9019785__F9 Proprietary Medicines Containing Bupleurum chinense DC. (Chaihu) for Depression: Network Meta-Analysis and Network Pharmacology Prediction ENSG00000087095 ENSG00000102871 ENSG00000127191 ENSG00000196712 ENSG00000026103 PMC4788585__F8 The EGF Receptor Ligand Amphiregulin Controls Cell Division via FoxM1 ENSG00000109321 ENSG00000146648 PMC5817861__F2 Cell signaling pathways induced by Src kinases ENSG00000291971 ENSG00000198793 ENSG00000168610 PMC8909308__F5 Transcriptome Differences in Normal Human Bronchial Epithelial Cells in Response to Influenza A pdmH1N1 or H7N9 Virus Infection ENSG00000002330 PMC8909308__F4 Transcriptome Differences in Normal Human Bronchial Epithelial Cells in Response to Influenza A pdmH1N1 or H7N9 Virus Infection ENSG00000101981 ENSG00000159224 ENSG00000213928 ENSG00000111537 ENSG00000111837 ENSG00000117758 ENSG00000125347 ENSG00000230034 ENSG00000026103 PMC2856809__F3 Dual MAG receptor model ENSG00000169783 PMC7563540__F2 Exosome biogenesis and release ENSG00000085117 ENSG00000074319 ENSG00000026508 ENSG00000010278 ENSG00000135404 PMC11049850__F3 Molecular mechanisms of LPS bacterial interaction with dental stem cells ENSG00000152592 ENSG00000172936 ENSG00000136869 PMC9161355__F1 Non-Coding RNAs Delivery by Small Extracellular Vesicles and Their Applications in Ovarian Cancer ENSG00000085117 ENSG00000110651 ENSG00000010278 ENSG00000135404 PMC10239924__F1 Raptor in lymphocytes differentiation and function ENSG00000150907 ENSG00000198793 ENSG00000155792 ENSG00000110931 ENSG00000167965 PMC7098264__F1 ApoE Isoform Specific Effects in AD ENSG00000130164 PMC9020986__F4 Immune cells in cardiac homeostasis and disease: emerging insights from novel technologies ENSG00000141448 ENSG00000126353 ENSG00000121807 ENSG00000145850 PMC8299307__F6 Schematic diagram demonstrating the novel signaling pathway involving EGFR–TRPM7 interaction in VSMCs ENSG00000092439 ENSG00000138798 ENSG00000146648 PMC3238295__F5 Bridged pairs and shared edges between 2ROs in the apoptosis pathway ENSG00000132906 ENSG00000002330 ENSG00000171791 ENSG00000168040 ENSG00000164305 ENSG00000276068 ENSG00000169618 ENSG00000100290 ENSG00000213999 ENSG00000135116 ENSG00000064012 ENSG00000104081 ENSG00000084774 PMC8337009__F4 ICN: extracting interconnected communities in gene co-expression networks ENSG00000142192 ENSG00000101474 ENSG00000108684 ENSG00000111837 ENSG00000163064 ENSG00000127191 PMC2075101__F1 5-HT2A receptor agonists cause activation of GAq/11 proteins which in turn activate the second messenger enzyme PLC ENSG00000182901 ENSG00000177606 ENSG00000168610 PMC4382094__F5 Na+/H+ Exchanger Isoform 1 Induced Cardiomyocyte Hypertrophy Involves Activation of p90 Ribosomal S6 Kinase ENSG00000285109 ENSG00000102119 PMC8299478__F1 Plasma LOX-Products and Monocyte Signaling Is Reduced by Adjunctive Cyclooxygenase-2 Inhibitor in a Phase I Clinical Trial of Tuberculosis Patients PMC7254656__F2 Main signaling pathways involved in CD19-BBζ T cells and CD19-28ζ T cells PMC3573348__F3 Ingenuity Pathway Analysis (IPA) of genes differentially expressed in LRECe vs ENSG00000112972 ENSG00000140575 ENSG00000108349 ENSG00000154001 ENSG00000205250 ENSG00000063244 ENSG00000055955 ENSG00000121774 ENSG00000124356 ENSG00000179295 ENSG00000137807 ENSG00000280858 ENSG00000071082 ENSG00000163558 ENSG00000196792 ENSG00000076321 ENSG00000053254 ENSG00000145349 ENSG00000163788 ENSG00000155090 PMC3573348__F5 Ingenuity Pathway Analysis (IPA) of genes differentially expressed in ECb vs ENSG00000122180 ENSG00000105193 ENSG00000147133 ENSG00000170606 ENSG00000181467 ENSG00000155313 ENSG00000076604 ENSG00000107581 ENSG00000070756 ENSG00000137947 ENSG00000150991 ENSG00000244687 ENSG00000196549 ENSG00000156096 ENSG00000125686 ENSG00000124783 PMC2374452__F5 Molecular pathways of rheumatoid arthritis-related cartilage destruction as reflected by the in vitro model ENSG00000262406 ENSG00000105664 ENSG00000081041 ENSG00000186340 ENSG00000163739 ENSG00000163734 ENSG00000166670 ENSG00000121807 ENSG00000117322 ENSG00000102172 ENSG00000121966 ENSG00000112486 PMC6872668__F8 Increased Smad3 and reduced Smad2 levels mediate the functional switch of TGFB from growth suppressor to growth and metastasis promoter through TMEPAI/PMEPA1 in triple negative breast cancer PMC2882531__F1 Retinoids for Treatment of Retinal Diseases ENSG00000135437 ENSG00000121207 ENSG00000116745 ENSG00000197713 ENSG00000080511 ENSG00000198691 PMC6783844__F1 The illustration of human IgG1 structure with N-glycan attached at Asn297 site in the CH2 of the Fc region ENSG00000069482 ENSG00000062485 PMC7507029__EV5 Graphical summary of LRP6‐YAP signaling pathway ENSG00000147162 ENSG00000281324 ENSG00000150457 ENSG00000131023 PMC8695855__F1 Pharmacological Applications and Action Mechanisms of Phytochemicals as Alternatives to Antibiotics in Pig Production ENSG00000136869 ENSG00000096717 PMC9335103__F4 Immune pathway upregulation and lower genomic instability distinguish EBV-positive nodal T/NK-cell lymphoma from ENKTL and PTCL-NOS ENSG00000160789 ENSG00000142512 ENSG00000120885 ENSG00000162437 ENSG00000138821 ENSG00000278494 ENSG00000139220 ENSG00000187908 ENSG00000162777 ENSG00000145850 ENSG00000166228 ENSG00000162896 ENSG00000023445 ENSG00000139193 ENSG00000197713 ENSG00000085117 ENSG00000146385 ENSG00000137757 ENSG00000126804 ENSG00000281022 ENSG00000275122 ENSG00000043591 ENSG00000198515 ENSG00000173221 ENSG00000133048 ENSG00000136960 ENSG00000178974 ENSG00000161860 ENSG00000198574 ENSG00000196199 ENSG00000163293 ENSG00000163898 ENSG00000198846 ENSG00000146070 ENSG00000119537 ENSG00000178199 ENSG00000282941 ENSG00000162144 ENSG00000163082 ENSG00000143553 ENSG00000163519 ENSG00000175220 ENSG00000135148 ENSG00000168032 ENSG00000158517 ENSG00000276798 ENSG00000111907 ENSG00000128165 ENSG00000248905 ENSG00000049130 ENSG00000115457 ENSG00000108474 ENSG00000173930 ENSG00000196235 ENSG00000166847 ENSG00000136068 ENSG00000121552 ENSG00000263639 ENSG00000141448 ENSG00000065361 ENSG00000109320 ENSG00000163874 ENSG00000104904 ENSG00000133835 ENSG00000232629 ENSG00000105953 ENSG00000114573 ENSG00000231925 ENSG00000184916 ENSG00000203857 ENSG00000072401 ENSG00000163131 ENSG00000049249 ENSG00000083799 ENSG00000135828 ENSG00000185973 ENSG00000139351 ENSG00000137675 ENSG00000165617 PMC12249970__F5 Activation of AhR by kynurenine, leading to the differential modulation of T cell subsets ENSG00000111537 ENSG00000140465 ENSG00000174611 ENSG00000106546 PMC12249970__F4 The AhR in modulating adaptive immune responses ENSG00000110711 ENSG00000049768 ENSG00000168610 ENSG00000106546 PMC12249970__F7 AhR and JAK/STAT pathway crosstalk in immune regulation ENSG00000111537 ENSG00000105397 ENSG00000113520 ENSG00000168610 ENSG00000090376 ENSG00000112486 ENSG00000106546 PMC2885902__F2 Mitochondrial biochemical pathways that are involved in KATP-independent GSIS ENSG00000065833 ENSG00000173599 ENSG00000079432 ENSG00000026103 PMC4311405__F5 Deregulation of signaling pathways and transcription factors ENSG00000129474 ENSG00000110330 ENSG00000116044 ENSG00000168036 ENSG00000111321 ENSG00000273686 ENSG00000168040 ENSG00000079999 ENSG00000083857 ENSG00000224320 ENSG00000136997 ENSG00000131323 ENSG00000105810 ENSG00000077782 ENSG00000064012 ENSG00000139687 ENSG00000146648 ENSG00000140443 PMC3104248__F3 Signaling molecules implicated in epilepsy (see the text for the detail) ENSG00000008710 ENSG00000002330 ENSG00000150907 ENSG00000169047 ENSG00000137193 ENSG00000123374 PMC3104248__F2 Genetic mutations of signaling molecules implicated in mTOR pathway (red Xs) ENSG00000266173 PMC3104248__F1 MTOR signaling pathway ENSG00000169047 PMC8132044__F1 What does elevated TARC/CCL17 expression tell us about eosinophilic disorders? ENSG00000159128 ENSG00000115415 ENSG00000102970 ENSG00000137265 ENSG00000027697 PMC3274456__F3 Lipopolysaccharide (LPS)-dependent and nuclear factor (NF)KB-mediated activation of proinflammatory cytokines ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC4588138__F1 Schematic of opportunities for host-directed therapies modulating eicosanoid balance PMC4252069__F6 Identification of MicroRNAs Linked to Regulators of Muscle Protein Synthesis and Regeneration in Young and Old Skeletal Muscle ENSG00000150907 ENSG00000198793 ENSG00000164327 ENSG00000141564 ENSG00000100664 ENSG00000148730 ENSG00000107581 PMC4160334__F1 Receptors and signaling pathways involved in proliferation and differentiation of Sertoli cells ENSG00000137090 ENSG00000291971 ENSG00000113070 ENSG00000171791 PMC8241768__F1 Molecular Genetics of Marfan Syndrome ENSG00000157933 PMC3573348__F2 Ingenuity Pathway Analysis (IPA) of genes differentially expressed in LRECb vs ENSG00000196843 ENSG00000070193 ENSG00000100883 ENSG00000147133 ENSG00000170606 ENSG00000066583 ENSG00000137947 ENSG00000141867 ENSG00000142677 ENSG00000033030 ENSG00000291483 ENSG00000196235 ENSG00000137440 ENSG00000168701 ENSG00000050130 ENSG00000198478 ENSG00000140262 ENSG00000136045 ENSG00000011260 ENSG00000100815 ENSG00000036828 ENSG00000163479 ENSG00000134574 ENSG00000133110 ENSG00000162775 ENSG00000119929 ENSG00000092108 ENSG00000214530 ENSG00000075303 ENSG00000102974 ENSG00000166860 PMC9479759__F5 Therapeutic potential of WKYMVm in diseases ENSG00000125538 ENSG00000169047 ENSG00000010278 ENSG00000168610 PMC9479759__F3 Therapeutic potential of WKYMVm in diseases ENSG00000187608 ENSG00000171049 ENSG00000112561 ENSG00000129226 PMC8571357__F7 PER2 mediates CREB-dependent light induction of the clock gene Per1 ENSG00000132326 ENSG00000179094 ENSG00000105662 PMC4223419__F1 Cellular pathways of prostaglandin (PG) metabolism ENSG00000095303 ENSG00000085662 ENSG00000148344 ENSG00000174640 ENSG00000164120 ENSG00000124212 ENSG00000073756 PMC6442998__F6 Potentiation of imatinib by cilostazol in sensitive and resistant gastrointestinal stromal tumor cell lines involves YAP inhibition ENSG00000145721 ENSG00000157404 ENSG00000172572 PMC2735047__F3 Graft-versus-Host Disease ENSG00000134982 PMC8993567__F4 Cellular and Molecular Mechanisms Involved in Hematopoietic Stem Cell Aging as a Clinical Prospect ENSG00000139193 ENSG00000007312 ENSG00000198793 ENSG00000265972 ENSG00000047936 ENSG00000132842 ENSG00000019582 ENSG00000164736 ENSG00000117091 ENSG00000076924 ENSG00000125538 ENSG00000104894 ENSG00000135404 ENSG00000196914 PMC5618564__F2 FAK-deleted keratinocytes demonstrate alterations in key mechanotransduction and collagen signaling pathways ENSG00000177238 PMC4396493__F2 No quiet surrender: molecular guardians in multiple sclerosis brain ENSG00000178573 ENSG00000079999 PMC7464415__F11 TLR3-dependent activation of MyD88 signaling: TLR3 activation triggers endogenous ligands of TLR2 (HMGB1 and Hsp60) via the usage of the MyD88 signaling pathway ENSG00000150782 ENSG00000189403 PMC10375937__F1 Cardioprotective effects of arjunolic acid in LPS-stimulated H9C2 and C2C12 myotubes via the My88-dependent TLR4 signaling pathway ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC4207397__F1 Dicarbonyl stress and RAGE signaling ENSG00000162692 PMC7998595__F1 Autophagy pathway in podocyte ENSG00000177169 ENSG00000156232 ENSG00000152409 ENSG00000150907 ENSG00000198793 ENSG00000284099 ENSG00000110931 ENSG00000112561 ENSG00000171791 ENSG00000145782 ENSG00000057663 PMC7338473__F1 Insulin receptor endocytosis in the pathophysiology of insulin resistance ENSG00000117399 PMC4295834__F4 Vascular remodeling after ischemic stroke: mechanisms and therapeutic potentials ENSG00000112715 ENSG00000121966 PMC7325485__F1 The dominant control mechanism by which Nrf2 activity is regulated occurs through its association with the E3 ubiquitin ligase KEAP1 and subsequent ubiquitination and proteasomal degradation ENSG00000083093 ENSG00000178573 ENSG00000284099 ENSG00000176153 ENSG00000247077 PMC8771834__F3 Insight of Autophagy in Spontaneous Miscarriage ENSG00000107562 ENSG00000112561 ENSG00000181652 ENSG00000164690 ENSG00000112715 PMC5349319__F3 Summary of identified microRNAs that target key proteins of autophagic pathway for regulation of autophagy ENSG00000177169 ENSG00000152348 ENSG00000110497 ENSG00000123395 ENSG00000198382 ENSG00000083290 ENSG00000144848 ENSG00000284099 ENSG00000145782 ENSG00000057663 PMC4742115__F5 Tumor-host signaling interaction reveals a systemic, age-dependent splenic immune influence on tumor development ENSG00000090402 ENSG00000118526 ENSG00000090776 ENSG00000104332 PMC10216337__F6 Schematic representing the suspected roles of and molecular pathways involving MeCP2 in prostate-cancer progression ENSG00000116717 ENSG00000122779 PMC10216337__F2 Schematic representing the suspected roles of and molecular pathways involving MeCP2 in colorectal-cancer progression ENSG00000145388 ENSG00000066336 ENSG00000073792 ENSG00000136826 ENSG00000165819 PMC10216337__F3 Schematic representing the suggested roles of and molecular pathways involving MeCP2 in pancreatic cancer ENSG00000131914 ENSG00000140564 ENSG00000170558 ENSG00000187772 PMC3684135__F1 Transforming growth factor B (TGFB) signaling pathway in hypothermia ENSG00000049323 ENSG00000137834 ENSG00000157933 ENSG00000005339 ENSG00000105329 ENSG00000109320 ENSG00000050748 ENSG00000138798 ENSG00000183691 ENSG00000120693 ENSG00000134363 ENSG00000020633 ENSG00000115221 ENSG00000168610 ENSG00000137801 ENSG00000136603 ENSG00000170365 ENSG00000160973 ENSG00000111537 ENSG00000118785 ENSG00000095739 ENSG00000177606 ENSG00000128342 PMC6167486__F1 Proposed roles for CXCR3 and its ligands in melanoma ENSG00000169248 ENSG00000169245 ENSG00000186810 ENSG00000134982 ENSG00000138755 PMC5618489__F7 Dynmics of starch biosynthetic pathway during development stages of pericarp and endosperm ENSG00000112977 ENSG00000197594 ENSG00000167701 PMC3228910__F2 Expanded representation of the KEGG pathway "colorectal cancer" ENSG00000002330 ENSG00000213658 ENSG00000134982 ENSG00000198670 ENSG00000095002 PMC8093597__F2 Immunological and physiopathological approach of COVID-19 in pregnancy ENSG00000134982 ENSG00000130234 ENSG00000188404 ENSG00000184012 PMC7226782__F4 GSK-3/Beta-catenin in sensing of cytosolic DNA by the cyclic GMP–AMP synthase (cGAS)/STING pathway ENSG00000183735 ENSG00000164430 ENSG00000168036 PMC4888568__F1 Model of insulin signalling pathway ENSG00000124102 ENSG00000291971 ENSG00000169047 PMC7707088__F1 Function and therapeutic potential of G protein‐coupled receptors in epididymis ENSG00000157554 ENSG00000001626 PMC5597136__F4 Known and recovered GRN for cell cycle pathway in yeast Saccharomyces cerevisiae ENSG00000261832 ENSG00000094804 ENSG00000197601 ENSG00000117399 PMC11806845__F1 Mitochondrial membrane permeabilization results in mtDNA leakage ENSG00000278718 ENSG00000130340 ENSG00000247077 PMC6383445__F2 Roles of PARPs in the immune response after pathogen invasion ENSG00000143799 ENSG00000059378 ENSG00000114127 ENSG00000173200 PMC5134704__F1 The plasticity of EZH2 in regulating MMP-mediated invasion pathway ENSG00000074266 ENSG00000178691 PMC3053348__F7 The Danger Signal S100B Integrates Pathogen– and Danger–Sensing Pathways to Restrain Inflammation ENSG00000239732 ENSG00000172936 ENSG00000164342 PMC8870198__F1 SMAD4 Inactivation in Epithelial–Mesenchymal Plasticity of Pancreatic Ductal Adenocarcinoma: The Missing Link? ENSG00000137834 ENSG00000070831 ENSG00000198793 PMC4730629__F7 Reactive oxygen species (ROS) pathway in bamboo ENSG00000105722 PMC9488800__F4 Multifaceted roles of the matrikine Pro-Gly-Pro in pulmonary health and disease ENSG00000226275 ENSG00000184207 PMC4599578__F6 Cancer-promoting GSNs in A) D-SWCNT, B) D-MWCNT and C) ASB neoplastic-like transformed SAECs ENSG00000087245 ENSG00000104365 ENSG00000162772 ENSG00000132170 ENSG00000145604 ENSG00000149311 ENSG00000136960 ENSG00000066336 ENSG00000292234 ENSG00000136997 ENSG00000026508 ENSG00000164400 ENSG00000134313 ENSG00000198625 PMC11806845__F6 Primary cytoplasmic DNA sensors activated by cytosolic mtDNA ENSG00000162711 ENSG00000124256 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000163568 ENSG00000158828 ENSG00000172936 ENSG00000285379 PMC11806845__F5 Dysfunction in mitophagy is closely related to mtDNA leakage ENSG00000158828 ENSG00000069329 ENSG00000069509 ENSG00000100219 ENSG00000062716 PMC8351231__F2 The Hippo signalling pathway ENSG00000167601 ENSG00000186575 ENSG00000109321 ENSG00000291971 ENSG00000144560 ENSG00000136997 ENSG00000163814 PMC8351231__F1 Different signaling pathways involved in resistance to EGFR tyrosine kinase inhibitors (TKIs) driven by Protein Kinase C delta (PKCD) and receptor tyrosine kinase recycling ENSG00000122218 ENSG00000163814 ENSG00000146648 PMC7105880__F1 Outline of the pathway of eicosanoid synthesis from arachidonic acid ENSG00000226275 PMC7793832__F2 NLRP3 inflammasome activation following non-canonical inflammasome activation ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC6851264__F8 Working model of the pathway to maturation of invadopodia when cancer cells are stimulated by transient tugging forces ENSG00000106683 ENSG00000149269 PMC5260963__F4 Protein interaction map ENSG00000132694 ENSG00000228716 ENSG00000101901 ENSG00000003436 ENSG00000187608 ENSG00000163431 ENSG00000187045 ENSG00000106436 ENSG00000158517 ENSG00000171791 ENSG00000236625 ENSG00000151276 ENSG00000086205 ENSG00000126218 ENSG00000104435 ENSG00000038427 ENSG00000198125 ENSG00000165471 ENSG00000274137 PMC4968084__F3 Unlike the 20S proteasome, the subunits of the Immunoproteasome lack functional EpRE binding domains, and so cannot be regulated by Nrf2 ENSG00000111537 ENSG00000115415 PMC8148124__F3 Calcium and Redox Liaison: A Key Role of Selenoprotein N in Skeletal Muscle ENSG00000100219 PMC5487386__F2 Signaling pathways in innate recognition of fungal pathogens and differentiation of CD4+ T helper cells ENSG00000096996 ENSG00000162711 ENSG00000138378 ENSG00000187796 ENSG00000027697 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000100365 PMC3148653__F3 Network of TP53-regulated genes ENSG00000167513 ENSG00000120889 ENSG00000175592 ENSG00000145386 ENSG00000076003 ENSG00000092820 ENSG00000124762 ENSG00000072571 ENSG00000138778 ENSG00000109084 ENSG00000011422 ENSG00000173535 ENSG00000123983 ENSG00000130513 ENSG00000198830 ENSG00000164109 ENSG00000113070 ENSG00000131747 ENSG00000073756 ENSG00000174307 ENSG00000198901 ENSG00000117650 ENSG00000118785 ENSG00000134057 ENSG00000109805 ENSG00000171848 ENSG00000100479 ENSG00000075218 ENSG00000100985 ENSG00000149554 ENSG00000095002 PMC3148653__F4 Network of HNF4A-regulated genes ENSG00000175573 ENSG00000163629 ENSG00000143228 ENSG00000176153 ENSG00000064933 ENSG00000164070 ENSG00000163435 ENSG00000006712 ENSG00000100412 ENSG00000050344 ENSG00000116679 ENSG00000189403 ENSG00000284944 ENSG00000090238 ENSG00000150630 PMC7933770__F2 PPI network of the DEGs, and the expression levels of the hub genes in PDAC tissues and normal tissues ENSG00000116106 ENSG00000157227 PMC3958334__F3 Functional Screen Reveals an Extensive Layer of Transcriptional and Splicing Control Underlying RAS/MAPK Signaling in Drosophila ENSG00000167258 ENSG00000124789 ENSG00000105401 ENSG00000108590 ENSG00000213741 ENSG00000140259 ENSG00000092847 ENSG00000168522 ENSG00000149273 ENSG00000130520 ENSG00000163681 ENSG00000205937 ENSG00000134548 ENSG00000113360 ENSG00000115540 PMC11359136__F2 HCMV regulates the classical Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC7969743__F3 Emerging role of ferroptosis in intestinal disease ENSG00000135423 ENSG00000151012 ENSG00000197635 ENSG00000124762 PMC5483997__F1 Emerging roles of the bone morphogenetic protein pathway in cancer: potential therapeutic target for kinase inhibition ENSG00000170365 ENSG00000137834 ENSG00000198742 ENSG00000163914 ENSG00000125968 PMC3932947__F7 En2 modulates IGF1’s pleiotropic effects in GNPs, potentially through altered S6 kinase activation ENSG00000164778 ENSG00000140443 PMC11359136__F3 HCMV regulates the Notch signaling pathway ENSG00000135547 ENSG00000137845 ENSG00000168610 PMC4420923__F10 Molecular mechanism for SGK1 signaling and cell survival PMC9031331__F4 Integrated Analysis of the miRNA-mRNA Regulatory Network Involved in HIV-Associated Neurocognitive Disorder ENSG00000125266 ENSG00000107562 ENSG00000213658 ENSG00000149269 ENSG00000010810 ENSG00000172602 ENSG00000067606 ENSG00000198517 ENSG00000164690 ENSG00000169242 ENSG00000196396 ENSG00000126458 PMC7290906__F1 Polyplex internalization pathways, driven by mediators, cytoskeleton movements, and GTPase signaling ENSG00000070831 ENSG00000149269 PMC8431517__F10 Network Pharmacology Study on Morus alba L. Leaves: Pivotal Functions of Bioactives on RAS Signaling Pathway and Its Associated Target Proteins against Gout ENSG00000188257 PMC1852238__F1 Role of the glutathione pathway and ABC-transporter family in drug elimination and defense from ROS-mediated oxidative stress ENSG00000103222 ENSG00000118777 PMC8755543__F7 Mechanism diagram of KDM4A-AS1 regulating the degradation of AR/AR-Vs ENSG00000101557 PMC11468005__F1 PI3K/AKT/ mTOR signaling pathway PMC6557399__F1 HMG-CoA reductase pathway ENSG00000291470 ENSG00000070831 ENSG00000163914 PMC4131144__F5 Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model ENSG00000131473 ENSG00000065833 ENSG00000073578 ENSG00000100412 ENSG00000005882 ENSG00000105953 ENSG00000075239 ENSG00000159399 PMC6161371__F3 Cooperation between c-Myc and YAP/TAZ or HSF1 cofactor (a) Phosphorilation of YAP/TAZ by Hippo signaling pathway promotes cytoplasmic localization and ubiquitin-mediated degradation ENSG00000284774 ENSG00000150457 ENSG00000131023 PMC9519344__F4 Mitochondrial Unfolded Protein Response: A Novel Protective Pathway Targeting Cardiomyocytes ENSG00000152348 ENSG00000128272 ENSG00000145782 ENSG00000057663 PMC7533892__F3 Consequences of IDH1/2-related cancer metabolism for redox homeostasis ENSG00000065833 ENSG00000086991 ENSG00000112992 ENSG00000142082 ENSG00000082212 PMC9519344__F3 Mitochondrial Unfolded Protein Response: A Novel Protective Pathway Targeting Cardiomyocytes ENSG00000128272 ENSG00000144895 PMC7098128__F2 Extracellular DNA in blood products and its potential effects on transfusion ENSG00000183735 ENSG00000239732 ENSG00000125538 PMC7533892__F5 2HG interference with the mTOR pathway and collagen maturation ENSG00000106397 ENSG00000198793 ENSG00000083444 ENSG00000155792 ENSG00000066135 ENSG00000164327 PMC6129574__F5 Metabolic pathway influenced by patulin and Protein interaction network of Kcr proteins ENSG00000291931 ENSG00000117133 ENSG00000147679 ENSG00000197756 ENSG00000156482 ENSG00000120885 ENSG00000126261 ENSG00000108107 ENSG00000182511 ENSG00000131238 ENSG00000008988 ENSG00000141101 ENSG00000113558 ENSG00000197498 ENSG00000112186 ENSG00000144713 ENSG00000158516 ENSG00000115268 ENSG00000162244 ENSG00000183691 ENSG00000163902 ENSG00000069329 ENSG00000167074 ENSG00000126749 ENSG00000291973 ENSG00000172809 ENSG00000101082 ENSG00000116649 PMC7698938__F5 Mechanisms of therapeutic effects of Cinacalcet on CKD-MBD ENSG00000152266 ENSG00000167941 ENSG00000132693 PMC8537491__F2 Cellular Signalling and Photobiomodulation in Chronic Wound Repair ENSG00000198742 ENSG00000198793 ENSG00000125968 PMC6859487__F1 Basic metabolic pathways used in T cells ENSG00000143158 ENSG00000135218 ENSG00000198793 ENSG00000060762 PMC9519344__F5 Mitochondrial Unfolded Protein Response: A Novel Protective Pathway Targeting Cardiomyocytes ENSG00000128272 ENSG00000100219 PMC8962202__F3 CIGB-300-Regulated Proteome Reveals Common and Tailored Response Patterns of AML Cells to CK2 Inhibition ENSG00000112576 ENSG00000164053 ENSG00000172590 ENSG00000196187 ENSG00000182180 ENSG00000278461 ENSG00000033800 ENSG00000198015 ENSG00000164162 ENSG00000108219 ENSG00000104872 ENSG00000170365 ENSG00000103479 ENSG00000106683 ENSG00000154237 PMC8718819__F1 Rho GTPase signaling in rheumatic diseases ENSG00000041982 ENSG00000070831 ENSG00000149968 ENSG00000149269 ENSG00000163914 ENSG00000116690 ENSG00000100985 ENSG00000168610 ENSG00000007171 PMC12179559__F3 Energy metabolism and signalling pathways involved in IMPDH2 ENSG00000087245 ENSG00000178035 ENSG00000134982 ENSG00000150907 ENSG00000198793 ENSG00000168036 ENSG00000100985 ENSG00000175104 PMC6104680__F6 Mechanisms of interaction between IL-6 and TGFB leading to fibrosis in SSc ENSG00000105397 ENSG00000291971 ENSG00000168610 PMC10899349__F1 IGF1/IGF1R axis and its downstream signaling pathway ENSG00000157764 ENSG00000198793 ENSG00000168036 ENSG00000140443 PMC6686084__F1 An example of cellular nutrient–gene interaction mechanisms ENSG00000099194 ENSG00000026103 PMC10203752__F3 Mechanisms of proanthocyanidins in treatment of HSP ENSG00000172936 ENSG00000136869 PMC10489316__F10 Targets-pathways network ENSG00000143799 ENSG00000070831 ENSG00000291971 ENSG00000164305 ENSG00000179295 ENSG00000180210 ENSG00000149968 ENSG00000128052 ENSG00000123374 ENSG00000105810 ENSG00000120868 ENSG00000077782 ENSG00000140443 ENSG00000148346 ENSG00000087245 ENSG00000171105 ENSG00000163220 ENSG00000007908 ENSG00000105639 ENSG00000007171 ENSG00000132170 ENSG00000143387 ENSG00000066468 ENSG00000115415 ENSG00000144566 ENSG00000100985 ENSG00000146648 ENSG00000178568 PMC11174683__F3 Mechanistic map of signaling pathways associated with NPs for liver cancer treatment ENSG00000117226 ENSG00000244405 ENSG00000132646 ENSG00000198793 ENSG00000026508 ENSG00000168036 ENSG00000164690 ENSG00000168646 ENSG00000168610 PMC11943704__F5 Plasma Proteomics and Metabolomics of Aromatase Inhibitors-Related Musculoskeletal Syndrome in Early Breast Cancer Patients ENSG00000169291 ENSG00000186395 ENSG00000186847 ENSG00000082175 ENSG00000160182 ENSG00000171791 ENSG00000147654 ENSG00000146648 ENSG00000171345 PMC7265486__F1 Stratification and prediction of drug synergy based on target functional similarity ENSG00000144857 ENSG00000146648 PMC5261008__F6 The multi-targeted STAT3 and TLR9 for aGvHD therapy ENSG00000239732 ENSG00000134982 ENSG00000168610 PMC5914062__F2 Schematic model illustrating the relationship between glucose metabolism and radiation resistance ENSG00000168610 PMC4671345__F3 LIF protects cardiac myocytes by both genomic and non-genomic means ENSG00000128342 ENSG00000168610 PMC11629383__F3 POU5F1P1 and NANOGP8, two processed pseudogenes encoding functional proteins ENSG00000169291 ENSG00000109321 ENSG00000105550 ENSG00000187837 ENSG00000168610 PMC5928437__F9 miR-103/107 promoted ER stress-mediated apoptosis via the Wnt3a/Beta-catenin /ATF6 pathway in preadipocytes ENSG00000154342 ENSG00000168036 ENSG00000171791 PMC11629383__F2 Truncated yet functional NOTCH2NL genes ENSG00000136997 ENSG00000113520 PMC8616319__F3 Immune Components on Stem Cell and Dormancy in Cancer ENSG00000108691 ENSG00000147419 ENSG00000100985 PMC12185661__F3 GPER signaling pathways ENSG00000113070 ENSG00000146648 PMC8375100__F1 Kynurenine pathway metabolites in cerebrospinal fluid and blood as potential biomarkers in Huntington's disease ENSG00000188676 PMC5541669__F3 Recurrent architecture of tumour initiation, progression and drug sensitivity ENSG00000105369 ENSG00000007312 ENSG00000198793 ENSG00000168610 ENSG00000010671 ENSG00000105397 ENSG00000115415 ENSG00000186716 ENSG00000137265 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000198286 PMC5919715__F8 PPI and miRNA-gene regulatory networks ENSG00000163637 ENSG00000154342 ENSG00000188386 ENSG00000163251 ENSG00000181274 ENSG00000188064 ENSG00000173218 ENSG00000174804 ENSG00000149782 ENSG00000104332 ENSG00000118971 PMC9284696__F2 Construction of a circular RNA-based competing endogenous RNA network to screen biomarkers related to intervertebral disc degeneration ENSG00000008710 ENSG00000169371 ENSG00000145217 ENSG00000119906 ENSG00000213741 ENSG00000140488 ENSG00000198040 ENSG00000110931 ENSG00000292219 ENSG00000179832 ENSG00000198156 ENSG00000291969 ENSG00000186334 ENSG00000164934 ENSG00000196136 ENSG00000164713 ENSG00000172216 ENSG00000213445 ENSG00000137261 ENSG00000149806 ENSG00000132819 ENSG00000213024 ENSG00000196233 ENSG00000155090 ENSG00000185633 ENSG00000288217 ENSG00000107566 ENSG00000173402 ENSG00000166033 ENSG00000105374 ENSG00000159921 ENSG00000147642 ENSG00000292348 ENSG00000167080 ENSG00000134824 ENSG00000102760 ENSG00000102312 ENSG00000188783 PMC9284696__F4 Construction of a circular RNA-based competing endogenous RNA network to screen biomarkers related to intervertebral disc degeneration ENSG00000105329 ENSG00000150907 ENSG00000134363 ENSG00000127528 ENSG00000135503 ENSG00000118971 PMC8804296__F1 Targeting Cell Death: Pyroptosis, Ferroptosis, Apoptosis and Necroptosis in Osteoarthritis ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC6899955__F1 Screening of Mtb virulence proteins that interact with proteins from macrophages ENSG00000153574 PMC8804296__F3 Targeting Cell Death: Pyroptosis, Ferroptosis, Apoptosis and Necroptosis in Osteoarthritis ENSG00000168040 PMC4884045__F1 Mammalian Hippo signaling ENSG00000186575 ENSG00000150457 ENSG00000131023 ENSG00000089225 PMC3411424__F4 AlzPathway on Payao system ENSG00000105664 ENSG00000090402 PMC3411424__F3 Binary-relation notation and key molecules of AlzPathway ENSG00000142192 ENSG00000198793 ENSG00000168036 ENSG00000136869 ENSG00000064300 PMC7054734__F9 CircNR3C1-Regulated Pathway in RPE CellsRed arrows indicate promotive function and green lines indicate suppressive function ENSG00000197713 ENSG00000198793 PMC7855613__F4 Glycosylation in oncogenic signaling pathways ENSG00000134982 ENSG00000138798 ENSG00000168036 PMC7682655__F10 Diagram presentation of the molecular mechanism ENSG00000115548 PMC10957617__F3 Versatile Mechanisms of STING ENSG00000164430 ENSG00000176986 ENSG00000159399 PMC4918597__F2 MiR-548, miR-27, miR-346, miR-218, miR-34a, miR-21, miR-22 and miR-29b promote the osteogenic differentiation of mesenchymal stem cells through Wnt/catenin, Notch, TNFA, TGFB/BMP signaling pathways ENSG00000134982 ENSG00000155011 ENSG00000168036 ENSG00000114315 ENSG00000158050 PMC7688515__F1 Immunometabolic pathway during mycobacterial infection ENSG00000125538 ENSG00000112561 PMC5526991__F5 Extended Kegg Pathway for PI3K-Akt signaling ENSG00000092758 ENSG00000112280 ENSG00000002330 ENSG00000058085 ENSG00000110799 ENSG00000189056 ENSG00000101680 ENSG00000169231 ENSG00000172037 ENSG00000137801 ENSG00000053747 ENSG00000105664 ENSG00000136457 ENSG00000041982 ENSG00000029559 ENSG00000118785 ENSG00000186340 ENSG00000113296 ENSG00000049089 PMC3781192__F1 Blood glutathione redox status and global methylation of peripheral blood mononuclear cell DNA in Bangladeshi adults ENSG00000173638 ENSG00000116984 PMC5834792__F3 Drug resistance in anaplastic lymphoma kinase‐rearranged lung cancer ENSG00000019991 ENSG00000065361 ENSG00000163235 ENSG00000146648 ENSG00000143924 PMC12049683__F6 TMAO inducing cell ferroptosis ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000115107 PMC9454744__F3 Small Nucleolar RNAs and Their Comprehensive Biological Functions in Hepatocellular Carcinoma ENSG00000066468 PMC4791320__F2 Energy balance signaling, leptin and insulin interaction with possible ciliary genes ENSG00000278195 ENSG00000171105 ENSG00000198793 ENSG00000115138 ENSG00000168610 PMC12049683__F5 TMAO inducing cell pyroptosis ENSG00000278718 ENSG00000162711 ENSG00000117118 PMC12049683__F4 TMAO inducing autophagic cell death ENSG00000128272 ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC12049683__F3 TMAO inducing cell Apoptosis ENSG00000162711 ENSG00000128272 ENSG00000100219 ENSG00000168610 ENSG00000160202 PMC3180702__F6 Transcriptional complexity of the mesenchymal-epithelial transition network ENSG00000170370 ENSG00000143867 ENSG00000075891 PMC10814071__F4 Regulatory Gene Network Associated with the Ameliorative Effect of Oat Antibacterial Peptides on Rat Colitis ENSG00000157933 ENSG00000198793 PMC5849426__F7 Putative model illustrating the interplay between RANK/NFKB-dependent and Hdac3-dependent control of mTEC development ENSG00000147862 ENSG00000171720 ENSG00000269404 ENSG00000135373 ENSG00000135605 ENSG00000137709 ENSG00000125813 PMC3641106__F8 Differential Use of TLR2 and TLR9 in the Regulation of Immune Responses during the Infection with Trypanosoma cruzi ENSG00000239732 PMC8703376__F2 Inositol Phosphates and Retroviral Assembly: A Cellular Perspective ENSG00000127080 ENSG00000274958 ENSG00000137825 ENSG00000107789 ENSG00000151151 PMC6958407__F4 Proposed model for modulations of Hippo pathway by PDEF ENSG00000150457 ENSG00000131023 PMC8833440__F1 Targeting Chronic Inflammation of the Digestive System in Cancer Prevention: Modulators of the Bioactive Sphingolipid Sphingosine-1-Phosphate Pathway ENSG00000063176 ENSG00000170989 ENSG00000180739 ENSG00000213694 ENSG00000125910 ENSG00000267534 ENSG00000183018 PMC6345631__F1 Hippo Pathway Regulates Caveolae Expression and Mediates Flow Response via Caveolae ENSG00000197905 ENSG00000177469 ENSG00000114978 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC3865655__F1 Caveolin-1 is a highly versatile regulator of cell signaling ENSG00000291971 ENSG00000168036 PMC8833440__F2 Targeting Chronic Inflammation of the Digestive System in Cancer Prevention: Modulators of the Bioactive Sphingolipid Sphingosine-1-Phosphate Pathway ENSG00000063176 ENSG00000163914 ENSG00000170989 ENSG00000213694 ENSG00000125910 ENSG00000267534 PMC6991676__F7 Hypothetical pathway related to the disease pathogenesis process ENSG00000136997 ENSG00000139687 ENSG00000124762 PMC7193445__F2 Examples of SLC mediated drug transport across the blood-brain barrier and in glioblastomas and neurons ENSG00000197375 ENSG00000103257 ENSG00000168610 PMC5067323__F1 Metabolic pathways associated with DA ENSG00000072210 ENSG00000123454 ENSG00000171759 PMC3907060__F4 Analyses of differentially expressed genes regulated by fasting in all three tissues revealing an involvement of p53 and Srebp signaling pathway ENSG00000131473 ENSG00000160752 ENSG00000067064 ENSG00000110921 ENSG00000134324 ENSG00000120437 ENSG00000167508 ENSG00000285069 ENSG00000095794 ENSG00000026103 PMC4346882__F3 Schematic depiction and overview of PI3K/AKT/PTEN signaling has been shown ENSG00000198793 ENSG00000168036 PMC10253150__F6 Wnt signaling pathway, including the canonical pathway, the pathway associated with cell polarity determination (Wnt/PCP), and an increase in intracellular Ca2+ (Wnt/Ca2+), whose genes were significantly regulated in the ZG zone ENSG00000004975 ENSG00000169071 ENSG00000181274 ENSG00000134982 ENSG00000149782 ENSG00000168036 ENSG00000175592 ENSG00000101266 ENSG00000135341 ENSG00000118971 ENSG00000167941 ENSG00000147869 ENSG00000155011 ENSG00000136997 ENSG00000104371 ENSG00000166501 ENSG00000185269 ENSG00000101333 ENSG00000168772 ENSG00000087095 ENSG00000138795 ENSG00000188386 ENSG00000107404 ENSG00000156076 ENSG00000292149 ENSG00000106483 ENSG00000276920 ENSG00000182621 ENSG00000175029 ENSG00000137841 ENSG00000140807 ENSG00000120910 ENSG00000221823 ENSG00000163904 ENSG00000180138 ENSG00000164736 ENSG00000148660 ENSG00000177606 ENSG00000102312 ENSG00000146122 ENSG00000076716 ENSG00000161202 ENSG00000131196 PMC10253150__F7 Biogenic amine synthesis signaling pathway, whose genes were characterized by expression significantly regulated in the adrenal medulla ENSG00000129167 ENSG00000123454 ENSG00000141744 ENSG00000087085 ENSG00000140287 ENSG00000171759 PMC3753466__F3 Skp2/Cks1 is induced by the TNFA/NFKB signaling pathway in nephropathy ENSG00000145604 ENSG00000104856 ENSG00000102871 ENSG00000127191 PMC4320441__F3 49 genes whose functional domains were changed by DAS exons ENSG00000157404 ENSG00000049130 ENSG00000186635 ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000198793 ENSG00000196914 ENSG00000146648 ENSG00000183495 ENSG00000160691 PMC4269730__F5 Transforming growth factor (TGF)-beta signaling pathway ENSG00000170365 ENSG00000137834 ENSG00000204217 PMC8138183__F2 Human Cytomegalovirus Host Interactions: EGFR and Host Cell Signaling Is a Point of Convergence Between Viral Infection and Functional Changes in Infected Cells ENSG00000115415 ENSG00000185591 ENSG00000146648 PMC8988234__F3 Targeting Cancer Cell Ferroptosis to Reverse Immune Checkpoint Inhibitor Therapy Resistance ENSG00000168003 ENSG00000092445 ENSG00000151012 ENSG00000167468 ENSG00000184500 PMC8988234__F2 Targeting Cancer Cell Ferroptosis to Reverse Immune Checkpoint Inhibitor Therapy Resistance ENSG00000167468 ENSG00000072274 ENSG00000197429 ENSG00000111684 ENSG00000102967 ENSG00000115107 PMC9489416__F9 MCU Inhibitor Ruthenium Red Alleviates the Osteoclastogenesis and Ovariectomized Osteoporosis via Suppressing RANKL-Induced ROS Production and NFATc1 Activation through P38 MAPK Signaling Pathway ENSG00000147614 ENSG00000156026 ENSG00000102575 ENSG00000175104 ENSG00000131196 ENSG00000143387 PMC2950025__F1 Models of mitotic exit in yeast ENSG00000136425 ENSG00000134982 PMC4234693__F2 Three Wnt-dependent pathways have been categorized: canonical Wnt/Beta-catenin and non-canonical Wnt/PCP as well as Wnt/Ca2+ pathways ENSG00000134982 ENSG00000168036 PMC4234693__F4 Influence of non-canonical Wnt signals on the MAPK pathway ENSG00000125398 ENSG00000149968 ENSG00000134982 ENSG00000168036 ENSG00000100985 PMC4234693__F3 Influence of canonical Wnt signals on the MAPK pathway ENSG00000154342 ENSG00000125398 ENSG00000070831 ENSG00000143878 ENSG00000134982 ENSG00000168036 PMC4234693__F5 Influence of MAPK signals on the Wnt pathway ENSG00000125398 ENSG00000134982 ENSG00000168036 PMC3193426__F1 DSB repair pathways and SUMO ENSG00000198887 ENSG00000132646 ENSG00000070950 PMC4511863__F6 Integrated genomic approaches identify major pathways and upstream regulators in late onset Alzheimer’s disease ENSG00000011600 ENSG00000146094 ENSG00000172936 ENSG00000136869 ENSG00000168610 ENSG00000007171 ENSG00000110077 PMC5045138__F2 During homeostatic conditions, the Keap1 proteins binds with the nuclear factor Nrf2, inhibiting its translocation to the nucleus and the induction of the transcription of Nrf2-dependent reading frames ENSG00000178573 ENSG00000079999 PMC7990372__F2 Illustration of the processes of iron uptake, storage, and efflux in the retinal pigment epithelium (RPE) cells ENSG00000010704 ENSG00000106327 ENSG00000181867 ENSG00000115107 PMC4511863__F1 Integrated genomic approaches identify major pathways and upstream regulators in late onset Alzheimer’s disease ENSG00000111537 ENSG00000154589 ENSG00000172936 ENSG00000125347 ENSG00000175104 PMC8441048__F7 Base excision repair causes age-dependent accumulation of single-stranded DNA breaks that contribute to Parkinson disease pathology PMC8292968__F2 Non approved pharmacological targets and interaction of selected profibrotic pathways in SSc myofibroblasts that are currently being evaluated in clinical trials ENSG00000186260 ENSG00000196588 ENSG00000105397 ENSG00000291971 ENSG00000163914 ENSG00000086991 ENSG00000198670 ENSG00000131724 ENSG00000168610 PMC7072578__F2 Autoimmune response signatures for ovarian cancer ENSG00000008710 ENSG00000276725 ENSG00000198382 ENSG00000110492 ENSG00000132824 ENSG00000186638 ENSG00000171940 ENSG00000117139 ENSG00000168036 ENSG00000141564 ENSG00000166851 ENSG00000229314 ENSG00000080546 ENSG00000092871 ENSG00000012048 ENSG00000196531 ENSG00000288411 ENSG00000074800 ENSG00000109084 ENSG00000078900 ENSG00000126803 ENSG00000108679 ENSG00000136997 ENSG00000168374 ENSG00000167967 ENSG00000116030 ENSG00000143499 ENSG00000132819 ENSG00000025293 ENSG00000162896 ENSG00000263238 ENSG00000182718 ENSG00000162613 ENSG00000104689 ENSG00000137075 ENSG00000100345 ENSG00000101361 ENSG00000100320 ENSG00000123219 ENSG00000019582 ENSG00000011304 ENSG00000034510 ENSG00000169067 ENSG00000285485 ENSG00000069345 ENSG00000138180 ENSG00000090238 ENSG00000198625 PMC4783934__F4 Six miRNAs and their target genes that are involved in milk fat metabolism in bovine mammary gland ENSG00000019582 ENSG00000161905 ENSG00000170522 ENSG00000138029 ENSG00000162493 ENSG00000095303 ENSG00000164120 ENSG00000124212 ENSG00000073756 ENSG00000115592 PMC6694157__F5 P53 signaling pathway (hsa04115) is extended in the weighted network ENSG00000110514 ENSG00000085982 ENSG00000167470 ENSG00000221955 ENSG00000099860 ENSG00000196470 ENSG00000171791 ENSG00000147854 ENSG00000229314 ENSG00000008853 ENSG00000284468 ENSG00000163472 ENSG00000160202 ENSG00000123999 ENSG00000103343 ENSG00000175054 ENSG00000078900 ENSG00000121851 ENSG00000213445 ENSG00000135049 ENSG00000158796 ENSG00000177519 ENSG00000178922 ENSG00000164344 ENSG00000149418 ENSG00000169594 ENSG00000113889 ENSG00000137075 ENSG00000158234 ENSG00000085117 ENSG00000100448 ENSG00000175793 ENSG00000163736 ENSG00000118816 ENSG00000150787 ENSG00000100228 ENSG00000101745 ENSG00000149311 ENSG00000146416 ENSG00000100387 ENSG00000114268 ENSG00000165775 ENSG00000124659 ENSG00000099326 ENSG00000164292 ENSG00000149547 ENSG00000100865 ENSG00000198586 PMC6590237__F1 Dorsal root ganglion (DRG) neurons branch out to the skin with transient receptor potential channel vanilloid 1 (TRPV1)/transient receptor potential channel ankyrin transmembrane protein 1 (TRPA1) and other receptors expressing ENSG00000104321 ENSG00000196689 PMC4013405__F3 nAChR-mediated signaling in lung squamous cell carcinomas and adenocarcinomas ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC7445810__F4 Interactions between the hypoxia inducible factor (HIF) and circadian pathways ENSG00000132326 PMC4790729__F2 Therapeutic Potential of Insulin-Like Growth Factor-1 in Central Nervous System Disorders ENSG00000002330 PMC4790729__F1 Therapeutic Potential of Insulin-Like Growth Factor-1 in Central Nervous System Disorders ENSG00000169047 ENSG00000198793 ENSG00000115904 PMC2991085__F2 Stress-Activated Cap’n’collar Transcription Factors in Aging and Human Disease ENSG00000178573 ENSG00000156273 ENSG00000079999 PMC2774738__F3 Specification of cell fate in the mammalian cochlea ENSG00000135547 ENSG00000106571 ENSG00000078579 ENSG00000164690 ENSG00000273529 ENSG00000283060 ENSG00000184916 ENSG00000114315 ENSG00000077782 ENSG00000125968 ENSG00000106003 ENSG00000172238 PMC4179613__F3 MicroRNAs expression profile in CCR6+ regulatory T cells ENSG00000110395 ENSG00000213658 ENSG00000010810 ENSG00000135446 PMC11914797__F5 BBR and its derivatives are involved in autophagy mechanisms ENSG00000177169 ENSG00000164430 ENSG00000126775 ENSG00000198793 ENSG00000155792 ENSG00000158828 ENSG00000112561 ENSG00000026508 ENSG00000167965 PMC2965188__F2 Nrf2 cytoprotective signaling pathway ENSG00000178573 ENSG00000100387 ENSG00000079999 PMC7833428__F6 Functional significance of activation of EGFR, IGF-1R, and B1-integrin receptor downstream signaling in wound healing ENSG00000169291 ENSG00000291971 ENSG00000146648 ENSG00000140443 PMC11914797__F2 BBR and its derivatives influence the mechanism of apoptosis PMC5996891__F5 Homology modeling of Staphylococcus aureus phenol-soluble modulins (PSMs) ENSG00000256646 ENSG00000041357 PMC7833428__F4 Extracellular PEPD induced expression of the B1-integrin receptor and IGF-1R signaling proteins in control and “scratched” fibroblast models ENSG00000169291 ENSG00000140443 PMC8589992__F6 Proposed working model of FATP5-mediated effects on HCC cells ENSG00000170558 ENSG00000198793 PMC3224200__F1 Contribution of chemoattractant GPCRs to glioma stem-like cell mediated tumorigenesis, invasion and angiogenesis express various GPCRs ENSG00000168610 ENSG00000146648 ENSG00000121966 PMC6335974__F1 Network displaying key genes involved in apoptosis, DSB repair, Fanconi anemia pathway and homologous recombination ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000134899 ENSG00000144554 ENSG00000115392 ENSG00000164362 ENSG00000051180 ENSG00000171791 ENSG00000164305 ENSG00000067369 ENSG00000139618 PMC3334602__F10 Putative signal transduction pathways regulating fruiting body development in C ENSG00000070831 ENSG00000163914 ENSG00000277273 PMC3774995__F2 Schematic representation of p30 functions ENSG00000149311 ENSG00000136997 ENSG00000123374 ENSG00000136869 PMC2792912__F6 Model of Six2 function during mouse pyloric sphincter development ENSG00000107779 ENSG00000090402 ENSG00000125398 PMC6989403__F8 PMEPA1a promotion of tumor progression is mediated by Hippo signaling ENSG00000069869 ENSG00000131023 PMC6161810__F1 Wound healing, cellular regeneration and plasticity: the elegans way ENSG00000070831 ENSG00000156026 ENSG00000170373 PMC8638406__F8 IL-17 Receptor C Signaling Controls CD4+ TH17 Immune Responses and Tissue Injury in Immune-Mediated Kidney Diseases ENSG00000163739 ENSG00000163702 PMC3221598__F3 Protease Regulation: The Yin and Yang of neural development and disease ENSG00000142192 ENSG00000291971 PMC8063444__F5 5-HT, produced by TPH2, regulates the serotonergic synapse pathway (a) and oxytocin signalling pathway (b) in the hypothalamus ENSG00000145864 ENSG00000152495 ENSG00000139287 ENSG00000138798 ENSG00000095303 ENSG00000127588 ENSG00000146648 PMC6918647__F3 Network analysis using Ingenuity Pathway Analysis (IPA) among 4 upregulated (a: HMGB1, HOXA13, SREBF2, MECOM) and 3 downregulated (b: NCOA2, CSHL1, HDAC5) transcription factors and differentially expressed genes due to onset of ketosis postpartum ENSG00000136603 ENSG00000125814 ENSG00000109084 ENSG00000134363 ENSG00000122779 ENSG00000157514 ENSG00000198911 ENSG00000106546 ENSG00000291368 PMC6446698__F1 PI3K signaling pathway: growth factors such as insulin stimulate tyrosine kinase receptors resulting in their autophosphorylation ENSG00000171105 ENSG00000002330 ENSG00000169047 ENSG00000265972 PMC6842518__F5 Proposed model depicting the underlying molecular mechanism by which aqueous bark extract of T ENSG00000135218 ENSG00000100219 PMC2856775__F1A Convergence of Pathways in TLR and IL-1R SignalingUpon activation, the IL-1 receptor dimerized with the IL-1 receptor accessory protein ENSG00000174125 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC5355421__F1 Schematic illustration representing the microglial intracellular Ca2+signaling mediated by canonical transient receptor potential 3 (TRPC3) channels and the tripartite synapse ENSG00000111537 ENSG00000167323 ENSG00000138741 PMC7184480__F2 Schematic diagram of the RAS in the lung showing the role of ACE2 as a key element in the counter-regulatory axis of the RAS (elements in green; reviewed in Arendse et al.) ENSG00000175054 ENSG00000130234 ENSG00000184012 PMC8910720__F3 Pathogenesis of Cardiac Fibrosis: A Review of Recent Progress ENSG00000137834 ENSG00000041982 ENSG00000136535 ENSG00000163914 PMC2957678__F1 Schematic view of HMGB1 signal transduction ENSG00000136997 ENSG00000189403 PMC6323259__F4 Schematic presentation of the proposed effects of melatonin against ANIT-induced intrahepatic cholestasis ENSG00000023909 ENSG00000079999 PMC9554150__F4 Immunopathogenesis and environmental triggers in coeliac disease ENSG00000111537 ENSG00000118503 ENSG00000204520 ENSG00000168610 PMC3573271__F1 Role of aryl hydrocarbnon receptor (AHR) signalling on CD4+ T cells ENSG00000115415 ENSG00000049768 ENSG00000106546 PMC9147806__F3 Evolutionary Dance between Innate Host Antiviral Pathways and SARS-CoV-2 ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000131323 ENSG00000121060 ENSG00000142166 PMC8918193__F7 S100A16 promotes acute kidney injury by activating HRD1-induced ubiquitination and degradation of GSK3B and CK1A ENSG00000188643 ENSG00000019991 ENSG00000134982 ENSG00000168036 PMC7895420__F1 Molecular pathways control protein synthesis and degradation in skeletal myocytes ENSG00000110497 ENSG00000198793 PMC11877274__F1 Mechanism and site of action of pharmacological agents targeting the IL-17 signalling pathway (figure created in BioRender.com). SABR, single-arm pilot study of brodalumab ENSG00000162594 ENSG00000056736 ENSG00000175104 ENSG00000163702 PMC9019350__F1 Sea Cucumber Compounds Targeting NFKB in Cancer Treatment ENSG00000112576 ENSG00000169429 ENSG00000111321 ENSG00000171791 ENSG00000100985 ENSG00000162692 ENSG00000118971 ENSG00000146648 ENSG00000121966 PMC4384696__F5 Indoleamine 2,3-dioxygenase pathways of pathgenic inflammation and immune escape in cancer ENSG00000198793 PMC7830279__F1 DSB end resection and repair pathway ENSG00000051180 PMC8572460__F1 Ferroptosis in lung cancer ENSG00000148346 ENSG00000138449 ENSG00000151012 ENSG00000116044 ENSG00000196839 ENSG00000072274 ENSG00000162772 ENSG00000102967 ENSG00000136381 ENSG00000118369 ENSG00000168003 ENSG00000128272 ENSG00000167468 ENSG00000111684 ENSG00000042286 ENSG00000127948 PMC8010074__F9 Craniofacial Development: Neural Crest in Molecular Embryology ENSG00000139219 ENSG00000125398 ENSG00000167941 ENSG00000162551 ENSG00000026508 ENSG00000168036 ENSG00000108821 ENSG00000163295 ENSG00000110693 PMC2841319__F1 Pathogenesis of kidney disease in systemic lupus erythematosus ENSG00000026508 ENSG00000122194 PMC6356271__F2 Terminal telomeric complex ENSG00000166340 ENSG00000149311 ENSG00000175054 ENSG00000178971 ENSG00000145912 ENSG00000257949 ENSG00000109534 ENSG00000291996 ENSG00000115263 ENSG00000164362 ENSG00000107960 ENSG00000128513 PMC7688515__F2 AMPK-mTOR axis in the co-regulation of autophagy and immunometabolism ENSG00000177169 ENSG00000125538 ENSG00000198793 ENSG00000168961 PMC5356795__F6 Identification of biomarker microRNAs for predicting the response of colorectal cancer to neoadjuvant chemoradiotherapy based on microRNA regulatory network ENSG00000132646 ENSG00000172005 ENSG00000123374 ENSG00000164754 ENSG00000166278 PMC3721632__F1 Th17 cell based vaccines in mucosal immunity ENSG00000162594 ENSG00000169248 ENSG00000169245 ENSG00000111537 ENSG00000163739 ENSG00000186716 ENSG00000125538 ENSG00000138755 ENSG00000162896 PMC3726942__F10 Roles of the autocrine angiotensin system in ER stress-induced apoptosis of alveolar epithelial cells ENSG00000175054 ENSG00000130234 PMC4070007__F1 Simplified diagram of the TLR-mediated and interferon (IFN)-mediated immunity in response to viruses ENSG00000164362 ENSG00000131323 ENSG00000276561 ENSG00000164342 PMC4077897__F1 Emerging potential of autophagy-based therapies in the treatment of cystic fibrosis lung infections ENSG00000094631 ENSG00000124102 ENSG00000110497 ENSG00000126775 ENSG00000196455 ENSG00000284099 ENSG00000001626 ENSG00000182667 PMC3208628__F5 Integrated Transcriptome and Binding Sites Analysis Implicates E2F in the Regulation of Self-Renewal in Human Pluripotent Stem Cells ENSG00000073584 ENSG00000281324 ENSG00000134982 ENSG00000168036 ENSG00000119969 ENSG00000088256 ENSG00000166484 ENSG00000135341 ENSG00000106459 ENSG00000066468 ENSG00000066117 ENSG00000160867 ENSG00000067606 ENSG00000143126 ENSG00000108604 ENSG00000077782 ENSG00000126458 PMC7697203__F14 Fundamental Concepts of Hydrogels: Synthesis, Properties, and Their Applications ENSG00000108849 ENSG00000062485 PMC3867386__F8 Pre-Symptomatic Activation of Antioxidant Responses and Alterations in Glucose and Pyruvate Metabolism in Niemann-Pick Type C1-Deficient Murine Brain ENSG00000065833 ENSG00000074800 ENSG00000067057 ENSG00000005882 ENSG00000082212 ENSG00000152556 PMC9455248__F5 Lipidomics and Transcriptome Reveal the Effects of Feeding Systems on Fatty Acids in Yak’s Meat ENSG00000065833 ENSG00000169710 ENSG00000140284 ENSG00000099194 PMC6553502__F2 Parallel Molecular Evolution in Pathways, Genes, and Sites in High-Elevation Hummingbirds Revealed by Comparative Transcriptomics ENSG00000164405 ENSG00000065518 ENSG00000073578 ENSG00000156467 ENSG00000110717 ENSG00000100554 ENSG00000105379 PMC5668198__F1 Neural Stem Cell-based Regenerative Approaches for the Treatment of Multiple Sclerosis ENSG00000019991 ENSG00000168329 ENSG00000239732 ENSG00000173599 PMC9454092__F6 Dysregulated myokines and signaling pathways in skeletal muscle dysfunction in a cigarette smoke–induced model of chronic obstructive pulmonary disease ENSG00000062485 PMC9637027__F2 A3A (A) and A3B (B) expression by HPV ENSG00000100387 ENSG00000126746 ENSG00000205250 ENSG00000185651 PMC6859461__F3 Cancer pathway analysis of DEPs ENSG00000002330 ENSG00000110514 ENSG00000111837 PMC4934079__F6 Model for how autophagy regulates Notch1 signaling pathway in biliary differentiation of hepatic progenitor cells ENSG00000148400 ENSG00000198793 ENSG00000168610 PMC7783467__F3 FGF19 and FGF21 treatment of NASH ENSG00000042832 ENSG00000160867 ENSG00000105550 ENSG00000167910 PMC10706690__F6 CPNE7 study schema related to EMT ENSG00000087245 ENSG00000149968 ENSG00000170558 ENSG00000178773 ENSG00000108821 PMC9263642__F5 UVB irradiation differential regulate miRNAs expression in skin photoaging ENSG00000087095 ENSG00000142192 ENSG00000101474 ENSG00000170458 ENSG00000102871 ENSG00000177606 ENSG00000130159 ENSG00000115718 ENSG00000127191 ENSG00000081189 ENSG00000010671 ENSG00000026103 PMC9021242__F6 Hippo signaling pathway in asthma ENSG00000137033 ENSG00000134982 ENSG00000145777 ENSG00000166090 ENSG00000267534 ENSG00000115009 PMC3469232__F1 Cholesterol is converted to pregnenolone by cytochrome P450scc inside steroidogenic mitochondria ENSG00000291971 PMC9021242__F2 Hippo signaling pathway in ALI ENSG00000070193 ENSG00000087245 ENSG00000188064 ENSG00000267534 PMC5345234__F5 MAP2K5-centered gene clusters exclusively based on pathway and physical interactions ENSG00000151702 ENSG00000064309 ENSG00000143379 ENSG00000086991 ENSG00000164136 ENSG00000121067 ENSG00000164400 ENSG00000105639 ENSG00000127948 ENSG00000140443 ENSG00000115607 PMC9021242__F1 Hippo signaling pathway ENSG00000144560 ENSG00000136997 ENSG00000150457 ENSG00000131023 PMC5345234__F4 CXCL5-centered gene network upregulated in astrocytes in response to Meth exposure ENSG00000136546 ENSG00000169248 ENSG00000275718 ENSG00000180772 ENSG00000122194 ENSG00000105668 ENSG00000169836 ENSG00000115607 ENSG00000169245 ENSG00000160321 ENSG00000155307 ENSG00000152192 ENSG00000072694 ENSG00000157087 ENSG00000075891 ENSG00000136689 ENSG00000143184 ENSG00000153002 PMC1579207__F3 Cadmium-induced regulation of SCFMet30 ENSG00000113558 ENSG00000099804 PMC9023560__F7 HGF/c-Met pathway facilitates the perineural invasion of pancreatic cancer by activating the mTOR/NGF axis ENSG00000019991 ENSG00000170558 ENSG00000198793 PMC5345234__F3 Connectivity of genes that were upregulated in astrocytes by Meth ENSG00000159166 ENSG00000169248 ENSG00000180772 ENSG00000137699 ENSG00000067798 ENSG00000187266 ENSG00000179295 ENSG00000235750 ENSG00000042813 ENSG00000172534 ENSG00000152454 ENSG00000283780 ENSG00000101958 ENSG00000140443 ENSG00000039600 ENSG00000147168 ENSG00000065361 ENSG00000050628 ENSG00000135903 ENSG00000181467 ENSG00000166278 ENSG00000157106 ENSG00000117724 ENSG00000157110 ENSG00000169245 ENSG00000109163 ENSG00000111537 ENSG00000152192 ENSG00000072694 ENSG00000110841 ENSG00000150672 ENSG00000065029 ENSG00000118482 ENSG00000168229 ENSG00000165409 ENSG00000080618 ENSG00000164398 ENSG00000127527 ENSG00000038945 ENSG00000143184 ENSG00000153002 PMC9630901__F12 Synergic Effect of Combined Therapy of Hyperbaric Oxygen and Adipose-Derived Mesenchymal Stem Cells on Improving Locomotor Recovery After Acute Traumatic Spinal Cord Injury in Rat Mainly Through Downregulating Inflammatory and Cell-Stress Signalings ENSG00000198793 ENSG00000172005 ENSG00000129226 ENSG00000172936 ENSG00000131095 ENSG00000175104 PMC11507121__F6 Transcription and expression analysis of genes related to wax synthesis pathway in leaves of ‘Ningqi I’ goji and ‘Huangguo’ goji ENSG00000147869 PMC6588834__F1 Examples of RRNPP pheromone signaling ENSG00000090402 ENSG00000254550 PMC3307000__F3 JNK signaling pathway regulates axonal transport and autophagy ENSG00000142192 ENSG00000150907 ENSG00000171791 PMC6128059__F1 Representation displaying the two different signaling pathways, RET-dependent (A) and RET-independent (B).In RET-dependent, glial cell line-derived neurotrophic factor (GDNF) binds directly to GDNF family receptor alpha (GFRA)1 ENSG00000010810 PMC3203674__F1 Coronin 2A-dependent LXR transrepression pathway in macrophages ENSG00000161956 ENSG00000171720 ENSG00000177606 ENSG00000136869 PMC7881844__F2 Loss-of-function (LOF) mutations in components of the insulin signaling pathway found in patients with syndromes characterized by severe insulin resistance ENSG00000171105 ENSG00000005882 ENSG00000150907 ENSG00000169047 ENSG00000136111 ENSG00000154415 PMC7821223__F5 Transcription-related gene network ENSG00000244405 ENSG00000019549 ENSG00000175592 PMC4121055__F1 Beyond NPM-ALK driven lymphomagenesis: alternative drivers in Anaplastic Large Cell Lymphoma ENSG00000148400 ENSG00000137265 ENSG00000156574 ENSG00000168610 PMC7821223__F4 Hsf1-regulated gene network ENSG00000142192 ENSG00000284774 ENSG00000151929 ENSG00000140403 PMC12079090__F10 PAX7 in Breast Cancer Prognosis and Its Mechanistic Involvement in the Wnt/B‐Catenin Pathway ENSG00000009709 ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC4202272__F1 RANK signaling pathways ENSG00000180694 ENSG00000170909 ENSG00000033327 ENSG00000077150 ENSG00000110395 ENSG00000082512 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000131196 ENSG00000135605 ENSG00000010671 PMC3938254__F7 Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis ENSG00000205250 PMC9181147__F4 Potential of Epigallocatechin Gallate (EGCG) in Targeting Autophagy for Cancer Treatment: A Narrative Review ENSG00000126775 ENSG00000023287 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC3433920__F4 Acute phase canonical pathway and corresponding acute phase reactants identified as significant for interaction effect ENSG00000196136 ENSG00000113905 ENSG00000113600 ENSG00000117601 ENSG00000145192 ENSG00000198793 ENSG00000168610 ENSG00000171560 ENSG00000132693 PMC5498655__F1 Metabolic and transport pathway for irinotecan (CPT-11) ENSG00000172831 ENSG00000134982 ENSG00000262243 PMC9024538__F2 Targeting Wnt/Beta-Catenin Pathways in Primary Liver Tumours: From Microenvironment Signaling to Therapeutic Agents ENSG00000169071 ENSG00000070831 ENSG00000100592 ENSG00000177606 PMC9224386__F4 Beneficial Effects of O-GlcNAc Stimulation in a Young Rat Model of Sepsis: Beyond Modulation of Gene Expression ENSG00000144063 ENSG00000100290 ENSG00000115008 ENSG00000135960 ENSG00000144857 ENSG00000141086 ENSG00000173039 ENSG00000213341 ENSG00000119912 ENSG00000100485 ENSG00000145244 ENSG00000084774 PMC11719737__F4 Molecular mechanisms of UBE2T in tumorigenesis ENSG00000144554 ENSG00000134982 ENSG00000077152 ENSG00000198793 ENSG00000115392 ENSG00000168036 PMC7897698__F2 Regulatory cascade of MIR211 involving the BRAF/ERK5/DUSP and PDK4 ENSG00000110330 PMC8822171__F3 Caffeine Therapy for Apnea of Prematurity: Role of the Circadian CLOCK Gene Polymorphism ENSG00000110711 ENSG00000291971 ENSG00000172005 ENSG00000106546 PMC7897698__F1 Model summarizing the regulation of MIR211 gene expression: MIR211 gene is nested within the TRMP1 transcript ENSG00000171791 ENSG00000134160 ENSG00000124209 ENSG00000156113 PMC3466981__F2 Ubiquitin ligase complexes SCF and APC/C in ubiquitin-mediated proteolysis of regulatory molecules essential for cell cycle control ENSG00000134982 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC3763710__F1 The p53 Pathway as a Target in Cancer Therapeutics: Obstacles and Promise ENSG00000274089 ENSG00000096717 PMC3360162__F4 Synthesis of eicosanoids and their actions in mast cells ENSG00000226275 PMC3466981__F3 The Ubiquitin Proteasome Pathway (UPP) in the regulation of cell cycle control and DNA damage repair and its implication in tumorigenesis ENSG00000149311 ENSG00000012048 ENSG00000051180 ENSG00000139618 PMC3360162__F2 Antigen-mediated chemotaxis ENSG00000100290 ENSG00000033327 ENSG00000213658 ENSG00000167323 ENSG00000163914 PMC6255774__F8 A simplified diagram of fatty acid synthesis, modification and assembly into triacylglycerol in developing Arabidopsis seeds ENSG00000087253 ENSG00000173599 ENSG00000153395 PMC3376408__F1 IL-2 release by DCs stimulation of PRRs triggers the calcineurin/NFAT pathway via PLCG2 and intracellular Ca2+ flux ENSG00000187796 ENSG00000197943 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC10136495__F3 Targeting TGFB signaling pathway in LC ENSG00000087245 ENSG00000136997 ENSG00000100985 ENSG00000112715 ENSG00000049768 PMC10136495__F2 TGFB signaling pathway in LC development and metastasis ENSG00000087245 ENSG00000124216 ENSG00000198793 ENSG00000163914 ENSG00000136997 ENSG00000100985 ENSG00000049768 ENSG00000112715 PMC11853202__F5 Schematic diagram displaying APOL1RRV-mediated downstream signaling pathway leading the activation of the RAS and participating in the progression of CKD PMC5047620__F6 Role of Dicer1-Dependent Factors in the Paracrine Regulation of Epididymal Gene Expression ENSG00000157060 ENSG00000179168 ENSG00000172404 ENSG00000173868 PMC9616754__F1 Amyloid B in the pathological mechanism of GNE myopathy ENSG00000159921 ENSG00000177169 ENSG00000142192 ENSG00000128272 ENSG00000165280 ENSG00000100219 ENSG00000140443 PMC5486101__F1 Schematic overview of the autophagic pathway and potential drug target points of the pathway ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC2743144__F1 mTORC1 signaling governs hematopoietic stem cell quiescence ENSG00000140464 ENSG00000109670 PMC5876722__F1 Oncogenic signaling networks by Kaposi’s sarcoma-associated herpesvirus ENSG00000124181 PMC5303891__F1 Development of a Reporter System for In Vivo Monitoring of Gamma-Secretase Activity in Drosophila ENSG00000138798 PMC10521544__F6 Network pharmacology and experimental verification-based strategy for exploring the mechanisms of luteolin in the treatment of osteosarcoma ENSG00000002330 ENSG00000110514 ENSG00000179091 ENSG00000124733 ENSG00000188404 ENSG00000121058 ENSG00000158104 ENSG00000084774 PMC8419240__F5 Arsenic: Various species with different effects on cytochrome P450 regulation in humans ENSG00000140465 ENSG00000106546 PMC10521544__F4 Luteolin-target-pathway network ENSG00000110330 ENSG00000110799 ENSG00000171791 ENSG00000183735 ENSG00000078900 ENSG00000169429 ENSG00000164400 ENSG00000136869 ENSG00000105810 ENSG00000140443 ENSG00000087245 ENSG00000213341 ENSG00000212916 ENSG00000169245 ENSG00000102245 ENSG00000172936 ENSG00000146648 ENSG00000147082 ENSG00000171855 ENSG00000125740 ENSG00000107562 ENSG00000105329 ENSG00000291971 ENSG00000138798 ENSG00000130522 ENSG00000050748 ENSG00000288174 ENSG00000169031 ENSG00000164399 ENSG00000101266 ENSG00000112715 ENSG00000135341 ENSG00000166851 ENSG00000164305 ENSG00000106546 ENSG00000149968 ENSG00000125538 ENSG00000128052 ENSG00000113520 ENSG00000123374 ENSG00000113525 ENSG00000026103 ENSG00000132906 ENSG00000100906 ENSG00000175793 ENSG00000109320 ENSG00000137193 ENSG00000173039 ENSG00000108691 ENSG00000111537 ENSG00000135446 ENSG00000177606 ENSG00000123143 PMC8886744__F2 Apolipoprotein A1 in PPAR Signaling Pathway for Nonalcoholic Fatty Liver Disease ENSG00000108691 ENSG00000136869 ENSG00000112115 ENSG00000026103 PMC8886744__F1 Apolipoprotein A1 in PPAR Signaling Pathway for Nonalcoholic Fatty Liver Disease ENSG00000132170 PMC7942223__F2 One-carbon metabolism, transmethylation reactions, folate cycle, and DNA demethylation ENSG00000139372 ENSG00000116984 PMC5954032__F1 PI3K/AKT/mTOR/S6K pathway plays a major role in the control of immune cell homeostasis ENSG00000177455 ENSG00000163599 ENSG00000155792 PMC11558907__F2 Function and main molecular mechanism of various adipokines on myocardial ischemia/reperfusion (I/R) injury ENSG00000177169 ENSG00000164430 ENSG00000135218 ENSG00000133878 ENSG00000134070 ENSG00000189403 ENSG00000136869 ENSG00000096717 ENSG00000168610 ENSG00000275031 PMC12062509__F7 Cancer-related pathways in cuproptosis ENSG00000121897 ENSG00000124608 ENSG00000136868 ENSG00000151012 ENSG00000123191 ENSG00000168036 ENSG00000090861 ENSG00000137714 ENSG00000110911 ENSG00000196628 PMC3944211__F1 Bone morphogenetic protein signaling in nephron progenitor cells ENSG00000177606 PMC12062509__F6 Cuproptosis ENSG00000121897 ENSG00000136868 ENSG00000182511 ENSG00000291958 ENSG00000123191 ENSG00000137714 ENSG00000110911 PMC8570568__F3 An ageing innate immune system may predispose a patient to severe COVID-19 ENSG00000169245 ENSG00000162711 ENSG00000108691 ENSG00000130234 PMC12062509__F4 Copper-induced cell death ENSG00000278718 ENSG00000177169 ENSG00000162711 ENSG00000136868 ENSG00000151012 ENSG00000137275 ENSG00000156709 ENSG00000198793 ENSG00000112561 ENSG00000057663 ENSG00000178607 ENSG00000167468 ENSG00000136869 ENSG00000100219 ENSG00000168404 ENSG00000285379 PMC12062509__F3 Copper in promoting tumor ENSG00000143799 ENSG00000182809 ENSG00000177169 ENSG00000087245 ENSG00000136868 ENSG00000083290 ENSG00000134982 ENSG00000157227 ENSG00000198793 ENSG00000177556 ENSG00000146648 ENSG00000057663 PMC7947037__F2 Betaine and choline status modify the effect of folic acid and creatine supplementation on arsenic methylation in a randomized controlled trial of Bangladeshi adults ENSG00000291507 ENSG00000173638 ENSG00000173599 ENSG00000116984 ENSG00000133027 PMC4268103__F1 Emerging roles of Notch signaling in liver disease ENSG00000125398 ENSG00000136997 ENSG00000168036 ENSG00000133961 ENSG00000137845 PMC4412274__F2 Mechanical forces influence growth rate ENSG00000131023 PMC4693579__F2 GLP‐1 and Wnt signalling in the regulation of bone formation (A) In the inactive state of the Wnt/B‐catenin pathway, Wnt is inhibited by a decoy receptor sFRP, where as its co‐receptor LRP5/6 binds to inhibitory protein sclerostin or Dkk ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000165879 ENSG00000168036 PMC8416891__F4 Transcriptional Profiling of Human Peripheral Blood Mononuclear Cells Stimulated by Mycobacterium tuberculosis PPE57 Identifies Characteristic Genes Associated With Type I Interferon Signaling ENSG00000187608 ENSG00000100906 ENSG00000109320 ENSG00000183486 ENSG00000111331 ENSG00000121060 PMC11062136__F1 Graphical model illustrating the complex roles of Cytokinin Response Factors (CRFs) in the trade-off between abiotic stress response and plant developmental processes ENSG00000127445 PMC8072655__F2 Nrf2 in Hearing Loss ENSG00000181019 PMC5566872__F8 Microglial responses to ischemia/reperfusion based on our in vitro and in vivo datasets ENSG00000184979 ENSG00000169245 ENSG00000213928 ENSG00000115415 ENSG00000183486 ENSG00000136869 ENSG00000111331 ENSG00000275095 ENSG00000142166 PMC4233146__F1 Dendritic Cells and B cells: Unexpected Partners in Th2 development ENSG00000226275 ENSG00000186716 ENSG00000107485 ENSG00000111321 PMC8742232__F3 Advances in the study of CDC42 in the female reproductive system ENSG00000070831 ENSG00000132341 PMC8742232__F2 Advances in the study of CDC42 in the female reproductive system ENSG00000106410 PMC7090118__F3 Hedgehog pathway activation through the primary cilium ENSG00000128602 PMC2933688__F3 EGFR signaling and NHEJ ENSG00000163235 ENSG00000138798 ENSG00000146648 PMC9435021__F3 Biological and neurological activities of astaxanthin ENSG00000132906 ENSG00000002330 ENSG00000178573 ENSG00000102871 ENSG00000023909 ENSG00000164305 PMC4700624__F2 Changes in the representation of IGF-Akt pathway ENSG00000108443 ENSG00000140443 PMC12104183__F4 Signaling pathways involved in the protection of H2S against PH ENSG00000026103 PMC3359746__F1 Several growth factor signals activate cell membrane receptor tyrosine kinases leading to activation of downstream interacting signal transduction pathways (PI3K/AKT, RAF/MAPK, and MTOR) ENSG00000169291 ENSG00000002330 ENSG00000198793 ENSG00000136997 ENSG00000171791 PMC3081824__F5 Transcriptome Profiling of Bovine Milk Oligosaccharide Metabolism Genes Using RNA-Sequencing ENSG00000254685 ENSG00000196968 ENSG00000196371 ENSG00000172728 ENSG00000101346 ENSG00000112699 ENSG00000130383 ENSG00000186866 ENSG00000001036 ENSG00000179163 PMC7536854__F2 Intracellular signaling pathways govern cell growth and proliferation ENSG00000177058 ENSG00000179632 PMC8275986__F1 Calcium, an Emerging Intracellular Messenger for the Hippo Pathway Regulation ENSG00000203485 ENSG00000166025 ENSG00000150457 ENSG00000131023 PMC9180620__F6 Could a Lower Toll-like Receptor (TLR) and NFKB Activation Due to a Changed Charge Distribution in the Spike Protein Be the Reason for the Lower Pathogenicity of Omicron? ENSG00000140564 ENSG00000130234 ENSG00000184012 ENSG00000172936 ENSG00000136869 ENSG00000276561 ENSG00000164342 PMC3081824__F3 Transcriptome Profiling of Bovine Milk Oligosaccharide Metabolism Genes Using RNA-Sequencing ENSG00000164414 ENSG00000064225 ENSG00000115488 ENSG00000008513 ENSG00000111728 ENSG00000160408 ENSG00000119899 ENSG00000070731 ENSG00000115525 ENSG00000126091 ENSG00000073849 ENSG00000095380 ENSG00000159921 ENSG00000170191 ENSG00000162139 ENSG00000111726 ENSG00000101638 ENSG00000148488 ENSG00000070526 ENSG00000113532 ENSG00000144057 PMC6985874__F1 SCF is highly expressed in IPF lungs and blood ENSG00000100906 ENSG00000137193 ENSG00000147604 ENSG00000105610 ENSG00000111816 ENSG00000168610 ENSG00000081189 PMC7176996__F5 Involvement of angelicin in several apoptotic pathways which promote cancer cell death ENSG00000198793 ENSG00000120868 ENSG00000168040 ENSG00000146648 PMC8966512__F1 Intestinal Wnt in the transition from physiology to oncology ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC3404158__F2A Ubiquitination and Phosphorylation in the Regulation of NOD2 signaling and NOD2-mediated Disease ENSG00000167207 ENSG00000157625 PMC5293764__F1 Carbohydrate metabolism in I ENSG00000177646 PMC6939200__EV5 Elucidation of WW domain ligand binding specificities in the Hippo pathway reveals STXBP4 as YAP inhibitor ENSG00000126016 ENSG00000166263 ENSG00000168036 PMC2397440__F8 Possible role of AICAR and compound C on the AMPK pathway and on glycolysis in CT-2A and astrocytes under low glucose conditions ENSG00000105664 ENSG00000198793 PMC7351732__F3 MYC regulation of essential amino acid and lipid metabolism ENSG00000131473 ENSG00000122966 ENSG00000113161 ENSG00000169710 ENSG00000103257 ENSG00000183077 PMC7351732__F4 MYC coordinates multiple metabolic events to activate nucleotide metabolism ENSG00000106348 ENSG00000178035 ENSG00000092621 ENSG00000135069 ENSG00000118520 ENSG00000146733 ENSG00000102967 ENSG00000116649 ENSG00000102172 ENSG00000084774 ENSG00000254550 ENSG00000116984 PMC8945563__F2 Immunotherapy for SMARCB1-Deficient Sarcomas: Current Evidence and Future Developments ENSG00000183735 ENSG00000164430 ENSG00000088888 PMC7846573__F7 FANCD2 modulates the mitochondrial stress response to prevent common fragile site instability ENSG00000128272 ENSG00000144554 PMC3940969__F2 TLR signaling pathways in cerebral IT ENSG00000174125 ENSG00000226275 ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC12089955__F5 Proposed mechanisms of action for L. sakei LB-P12 in OA PMC7753186__F2 Mechanisms involved in SARS-CoV-2 infection delineating an ACE/ACE2-ATR1-Cholesterol-HDAC axis ENSG00000130234 PMC9318366__F6 Inosine Pretreatment Attenuates LPS-Induced Lung Injury through Regulating the TLR4/MyD88/NFKB Signaling Pathway In Vivo ENSG00000115271 ENSG00000005381 PMC3532163__F4 Characterization of the Phosphoproteome in SLE Patients ENSG00000087095 ENSG00000172680 ENSG00000170458 ENSG00000138798 ENSG00000177606 ENSG00000130159 ENSG00000127191 ENSG00000146648 ENSG00000026103 PMC9085228__F3 miRNA-142-3p functions as a potential tumor suppressor directly targeting FAM83D in the development of ovarian cancer ENSG00000111837 ENSG00000198793 ENSG00000015285 ENSG00000101447 PMC5610219__F2 Multiple miRNA biogenesis pathways ENSG00000164902 ENSG00000092847 ENSG00000124571 ENSG00000113360 ENSG00000134698 ENSG00000123908 PMC3748257__F2 STAT signaling in mammary gland differentiation, cell survival and tumorigenesis ENSG00000115415 PMC4057083__F8 On the Crucial Cerebellar Wound Healing-Related Pathways and Their Cross-Talks after Traumatic Brain Injury in Danio rerio ENSG00000066468 ENSG00000186810 ENSG00000126353 ENSG00000105639 ENSG00000077782 ENSG00000121966 ENSG00000064300 ENSG00000130827 PMC9142129__F6 Inference of Molecular Regulatory Systems Using Statistical Path-Consistency Algorithm ENSG00000170458 ENSG00000130522 ENSG00000149269 ENSG00000130159 ENSG00000175104 ENSG00000127191 ENSG00000196712 ENSG00000026103 PMC8067389__F3 HCMV dysregulates the Notch signaling pathway ENSG00000148400 ENSG00000273529 ENSG00000184916 ENSG00000114315 ENSG00000168610 PMC8067389__F2 HCMV regulates the canonical Wnt/Beta-catenin signaling pathway ENSG00000134982 ENSG00000168036 PMC3131147__F2 Possible pathways to androgen independence and the involvement of ANG ENSG00000198793 PMC7330701__F4 Schematic that illustrates the hypothesis of how the interferon tau (IFN-τ) acts on positive HPV 16 tumor cells ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000168610 ENSG00000142166 PMC5372499__F3 USP15 acts as a “biological thermostat” in the TGFB signaling pathway ENSG00000135655 PMC10886030__F4 Oxidative inactivation of PTEN in insulin-related metabolism and muscle differentiation ENSG00000138798 ENSG00000198793 PMC5385041__F4 Diagram of glycolysis is shown, including enzymes whose transcripts were more highly expressed in GRMD (red) or wild type dogs (green) ENSG00000180210 ENSG00000125166 ENSG00000130957 ENSG00000143158 ENSG00000074800 ENSG00000100994 ENSG00000292099 ENSG00000119899 ENSG00000166816 ENSG00000169299 ENSG00000060762 PMC6356247__F2 Effects of chemotherapy on coagulation activation ENSG00000134982 ENSG00000173599 PMC8108341__F9 Activation of the clock gene TIMELESS by H3k27 acetylation promotes colorectal cancer tumorigenesis by binding to Myosin-9 ENSG00000111602 ENSG00000138795 ENSG00000168036 PMC6533072__F3 Estrogen biosynthesis pathway ENSG00000108786 ENSG00000203859 PMC5770148__F1 Tibim1 reduces TLR4-dependent liver damage ENSG00000166402 ENSG00000136869 ENSG00000135926 PMC8620763__F1 Salicylic Acid and Risk of Colorectal Cancer: A Two-Sample Mendelian Randomization Study ENSG00000114200 ENSG00000066813 PMC7482583__F1 LRRK2’s potential involvement in pre- and post-synaptic pathways ENSG00000143553 ENSG00000069329 PMC2518463__F2 Binding of specific signalling proteins to phosphorylated tyrosine residues on KIT following receptor activation and the subsequent signalling events leading to mast cell responses ENSG00000157404 ENSG00000115415 ENSG00000010810 ENSG00000168610 ENSG00000010671 PMC6063270__F6 Repeated Cis-Regulatory Tuning of a Metabolic Bottleneck Gene during Evolution ENSG00000069482 ENSG00000169299 PMC4104311__F2 Small System—High-Resolution Study of Metabolic Adaptation in the Central Metabolic Pathway to Temperate Climates in Drosophila melanogaster ENSG00000125166 ENSG00000173599 ENSG00000213614 ENSG00000118094 ENSG00000146701 PMC6063270__F1 Repeated Cis-Regulatory Tuning of a Metabolic Bottleneck Gene during Evolution ENSG00000069482 ENSG00000169299 PMC8235519__F8 Comparative Analysis of Flavonoid Metabolites in Foxtail Millet (Setaria italica) with Different Eating Quality ENSG00000104899 ENSG00000108960 ENSG00000291631 PMC8473084__F5 Recombinant Antigen of Type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV-2) Promotes M1 Repolarization of Porcine Alveolar Macrophages and Th1 Type Response ENSG00000184979 ENSG00000088888 ENSG00000187608 ENSG00000156587 ENSG00000183486 ENSG00000111837 ENSG00000157601 ENSG00000083799 ENSG00000171791 ENSG00000127948 PMC8473084__F4 Recombinant Antigen of Type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV-2) Promotes M1 Repolarization of Porcine Alveolar Macrophages and Th1 Type Response ENSG00000213658 ENSG00000171540 ENSG00000139154 ENSG00000074266 PMC6541219__F1 Diagnosis and management of pseudohypoparathyroidism and related disorders: first international Consensus Statement ENSG00000152266 ENSG00000104447 ENSG00000113448 PMC2939609__F3 Molecular interactomes and sub-networks associated with tumor cell susceptibility to arsenic trioxide ENSG00000198830 ENSG00000058085 ENSG00000120149 ENSG00000159461 ENSG00000163565 ENSG00000023902 ENSG00000064547 ENSG00000175029 ENSG00000136826 ENSG00000111907 ENSG00000132170 ENSG00000109854 ENSG00000117713 ENSG00000115884 ENSG00000112242 ENSG00000160293 ENSG00000125968 ENSG00000136068 ENSG00000189079 PMC9267007__F1 Erythropoietin in Optic Neuropathies: Current Future Strategies for Optic Nerve Protection and Repair ENSG00000186716 ENSG00000168036 ENSG00000187266 ENSG00000168610 PMC4028332__F2 After the banquet ENSG00000100811 ENSG00000109819 ENSG00000162409 ENSG00000136997 ENSG00000158828 ENSG00000181220 ENSG00000196365 ENSG00000096717 PMC5050441__F33 Multitargeted modulation of estrogen carcinogenesis by botanicals ENSG00000172005 ENSG00000106546 ENSG00000079999 PMC7595250__F2 Cellular signaling pathways involved in cell senescence in renal ageing ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000096717 PMC8860249__F2 Emerging Roles of Pellino Family in Pattern Recognition Receptor Signaling ENSG00000172936 ENSG00000136869 ENSG00000162924 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC9179306__F5 Identification of the Key Genes Associated with Different Hair Types in the Inner Mongolia Cashmere Goat ENSG00000070388 ENSG00000144063 ENSG00000019995 ENSG00000171403 ENSG00000105550 ENSG00000087074 ENSG00000262164 ENSG00000203783 ENSG00000171446 ENSG00000125780 ENSG00000108179 ENSG00000163207 ENSG00000170484 ENSG00000205186 ENSG00000262068 ENSG00000111291 ENSG00000143536 ENSG00000159450 ENSG00000002549 ENSG00000182591 ENSG00000159495 ENSG00000277276 PMC6587965__F1 Cellular Signaling Pathways Modulated by Low-intensity Extracorporeal Shock Wave Therapy ENSG00000291971 ENSG00000198793 PMC9326486__F1 Therapeutic Potential of Targeting NIK in B Cell Malignancies ENSG00000104856 ENSG00000131323 ENSG00000127191 PMC6299370__F1 The activation of Wnt/Beta-catenin signaling by different oncogenic lncRNAs in liver cancer ENSG00000178585 ENSG00000134982 ENSG00000168036 ENSG00000102974 PMC4517123__F2 Innate immune sensing of rhabdovirus infection ENSG00000183735 ENSG00000131323 ENSG00000168040 ENSG00000276561 PMC9097822__F1 Signalling dynamics, cell decisions, and homeostatic control in health and disease ENSG00000182585 ENSG00000109321 ENSG00000163235 ENSG00000124882 ENSG00000113070 ENSG00000138798 ENSG00000158458 ENSG00000169752 PMC4999628__F5 A model for a role for AIISp in the repair of DNA ICLs ENSG00000012061 ENSG00000144554 PMC6485480__F1 Selectin ligand sialyl-Lewis x antigen drives metastasis of hormone-dependent breast cancers ENSG00000153936 ENSG00000182197 ENSG00000176928 ENSG00000109956 ENSG00000285395 ENSG00000164100 ENSG00000187210 ENSG00000002587 ENSG00000064225 ENSG00000176597 ENSG00000008513 ENSG00000176022 ENSG00000272916 ENSG00000285222 ENSG00000070731 ENSG00000126091 ENSG00000140297 ENSG00000151348 ENSG00000158008 ENSG00000136720 ENSG00000140835 ENSG00000196371 ENSG00000070526 ENSG00000180549 ENSG00000130383 ENSG00000158470 ENSG00000148154 PMC4213475__F2 Model of the JAK-STAT pathway in CRC with the corresponding significant changes in the signaling circuit activities ENSG00000114737 ENSG00000136997 ENSG00000142273 ENSG00000180008 ENSG00000282891 PMC4213475__F4 Signaling changes in the T-Cell receptor signaling pathway of human bone marrow hematopoietic stem cells ENSG00000104365 ENSG00000213658 ENSG00000081237 ENSG00000102245 ENSG00000010810 ENSG00000148204 ENSG00000142273 ENSG00000113263 ENSG00000043462 PMC2716793__F3 Spatial complexity and control of a bacterial cell cycle ENSG00000178209 ENSG00000112378 ENSG00000177084 PMC10311615__F11 18Beta-glycyrrhetinic acid inhibits proliferation of gastric cancer cells through regulating the miR-345-5p/TGM2 signaling pathway ENSG00000188554 ENSG00000198793 ENSG00000284099 PMC9018123__F4 Putative functions of EpsK in teichuronic acid synthesis and phosphate starvation in Bacillus licheniformis ENSG00000105664 PMC8000623__F2 Summary of survival tactics of MAH within phagocytes from host innate immune effectors MAH infection ENSG00000101160 ENSG00000170310 ENSG00000177606 ENSG00000132842 PMC12205806__F1 Part 1: The process of HBV infection and replication in cells: (A) HBV enters the liver cell via fusion and endocytosis ENSG00000168036 PMC5026573__F6 JNK pathway activation modulates acquired resistance to EGFR/HER2 targeted therapies ENSG00000132478 ENSG00000146648 ENSG00000140443 PMC6637517__F6 Model depicting cascade of the anti-inflammatory effect of ciprofloxacin and levofloxacin, targeting TLR4–MD-2 complex ENSG00000170458 ENSG00000125538 ENSG00000136869 PMC2949900__F4 Cell Cycle Pathway: Differentially expressed genes involved in the cell cycle are shown in pink ENSG00000145604 ENSG00000144063 ENSG00000124102 ENSG00000142230 ENSG00000132646 ENSG00000123374 ENSG00000164754 PMC6425072__F2 Neurotrophic factors and their receptors in dopamine neurons ENSG00000242689 ENSG00000187871 ENSG00000122756 ENSG00000185267 ENSG00000128342 ENSG00000171119 ENSG00000130513 PMC6716105__F7 Mechanism of the NFKB Signaling Pathway Mediated by LINC01093Overexpression of LINC01093 can target ICAM-1 negatively and then inhibit apoptosis and enhance proliferation by suppressing the NFKB signaling pathway, thereby attenuating AH ENSG00000164305 PMC10755684__F2 Neuroinflammation in the transition of acute to chronic pain and the opioid-induced hyperalgesia and tolerance ENSG00000108342 ENSG00000184371 PMC10853261__F8 Proposed model of GC-induced adiposity ENSG00000119138 ENSG00000088727 ENSG00000118520 ENSG00000073756 ENSG00000168610 ENSG00000169375 PMC2929731__F8 cAMP-activated Ca2+ signaling is required for CFTR-mediated serous cell fluid secretion in porcine and human airways ENSG00000161798 ENSG00000146469 ENSG00000001626 ENSG00000171885 PMC3733265__F1 Mimicking the BH3 domain to kill cancer cells ENSG00000002330 ENSG00000104081 PMC3072784__F8 A kinase cascade regulating pIgR transcytosis ENSG00000103769 ENSG00000146648 ENSG00000162896 PMC4530307__F1 “aggressive pathway.” Up-regulated genes (red) and downregulated genes (blue) are interconnected in a pathway involved in cell cycle control ENSG00000109854 ENSG00000072571 ENSG00000146670 ENSG00000138778 ENSG00000134057 ENSG00000178999 ENSG00000136997 ENSG00000074319 ENSG00000149091 ENSG00000026508 ENSG00000123219 ENSG00000137801 PMC7927668__F5 KEGG mTOR signaling pathway map comparing +AMR/+DSA and +DSA vs ENSG00000172680 ENSG00000176641 ENSG00000164654 PMC5345234__F9 IL2RG-centered gene subnetwork ENSG00000100612 ENSG00000106785 ENSG00000090104 ENSG00000119535 ENSG00000147168 ENSG00000065361 ENSG00000197471 ENSG00000143839 ENSG00000232326 ENSG00000187266 ENSG00000141968 ENSG00000179295 ENSG00000172534 ENSG00000150672 ENSG00000184634 ENSG00000102239 ENSG00000140443 ENSG00000111224 ENSG00000122515 ENSG00000188783 PMC8451771__F3 Apoptosis – Fueling the oncogenic fire ENSG00000164430 ENSG00000070831 ENSG00000168610 PMC8466405__F4 Pathophysiological Implication of Pattern Recognition Receptors in Fetal Membranes Rupture: RAGE and NLRP Inflammasome ENSG00000172936 ENSG00000150455 PMC2612938__F2 Pathways by which Mgrn1-mediated ubiquitination could modulate melanocortin receptor regulation of pigment production and energy metabolism ENSG00000149311 ENSG00000102858 ENSG00000124089 ENSG00000166603 PMC8468592__F2 Glucocorticoid and PD-1 Cross-Talk: Does the Immune System Become Confused? ENSG00000134982 ENSG00000107485 ENSG00000123374 PMC5589626__F7 Hyperactivated mTORC1 downregulation of FOXO3a/PDGFRA/AKT cascade restrains tuberous sclerosis complex-associated tumor development ENSG00000169047 ENSG00000198793 ENSG00000155792 ENSG00000134853 ENSG00000167965 PMC5995077__F7 DMix regulates hepatic gluconeogenesis in diabetic rats via the PI3K/Akt signaling pathway ENSG00000171105 ENSG00000150907 PMC7775273__F5 Mechanical Regulation of Apoptosis in the Cardiovascular System ENSG00000132906 ENSG00000102871 ENSG00000168040 ENSG00000064012 ENSG00000164305 PMC4825184__F1 TLR and NLR pathways driving pro-inflammatory state after exposure to extracellular and Intracellular microbial products ENSG00000187554 ENSG00000172936 ENSG00000106100 ENSG00000142224 PMC4641903__F2 Summary of the roles of alpha-synuclein and other PD-associated proteins in the secretory pathway and the resulting stress responses ENSG00000174903 ENSG00000168374 ENSG00000158828 ENSG00000103769 ENSG00000100219 PMC3654375__F3 Guidance from above: common cues direct distinct signaling outcomes in vascular and neural patterning ENSG00000107338 PMC8411019__F2 Specialized Proresolving Mediators for Therapeutic Interventions Targeting Metabolic and Inflammatory Disorders ENSG00000170775 ENSG00000133067 ENSG00000171049 ENSG00000069667 PMC3983859__F6 Schematic representation of the RvD1 contribution to microglia alternative activation ENSG00000171049 ENSG00000118520 PMC5510550__F1 Negative Regulation of Type 2 Immunity ENSG00000137033 ENSG00000145777 ENSG00000166090 PMC4280507__F4 One carbon metabolism and the effects of alcohol (EtOH) and nutrition throughout the metabolical pathway ENSG00000228716 ENSG00000116984 PMC3674144__F1 New look at TCR signaling to NFKB ENSG00000104856 ENSG00000197530 ENSG00000083799 ENSG00000051128 ENSG00000175104 ENSG00000127191 PMC6478801__F8 SNG mediated action in MM cells ENSG00000113600 ENSG00000171791 ENSG00000168610 PMC7280204__F8 Signaling pathways involved in osteocyte mechanobiology ENSG00000291971 ENSG00000167941 ENSG00000125384 ENSG00000163914 ENSG00000165879 ENSG00000143387 PMC4358122__F5 Reciprocal regulation of AMPK and PLD PMC4367691__F1 ROR1 signaling pathway ENSG00000157764 ENSG00000065361 ENSG00000138798 ENSG00000185483 ENSG00000168610 ENSG00000146648 PMC6329812__F2 The stress adaptive processes induced by mutant p53 trigger positive loops feeding its own accumulation in cancer cells ENSG00000094631 ENSG00000284774 PMC4931093__F1 Mechanotransduction in transcriptional regulation ENSG00000126016 ENSG00000172005 ENSG00000168036 PMC4237867__F1 Signaling pathway of toll-like receptors (TLRs) ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC2895650__F1 Multi-Variant Pathway Association Analysis Reveals the Importance of Genetic Determinants of Estrogen Metabolism in Breast and Endometrial Cancer Susceptibility ENSG00000156096 PMC6080105__F1 Short and Long Noncoding RNAs Regulate the Epigenetic Status of Cells ENSG00000074181 ENSG00000172346 ENSG00000092847 ENSG00000168495 PMC3943799__F2 Cytosolic DNA sensing pathways ENSG00000088888 ENSG00000163568 ENSG00000163565 ENSG00000168036 ENSG00000174953 ENSG00000172936 ENSG00000276561 PMC3819657__F3 Combined miRNA/mRNA regulatory and functional enrichment network ENSG00000159216 ENSG00000144810 ENSG00000141480 ENSG00000124882 ENSG00000134326 ENSG00000137193 ENSG00000171608 PMC4880707__F1 Suggested positive feedback loop in SOD3 signal transduction ENSG00000157764 ENSG00000291971 ENSG00000010810 ENSG00000112715 PMC5580463__F4 PI3K/AKT and RAS/EGFR/ERK pathways ENSG00000002330 ENSG00000065361 ENSG00000198793 ENSG00000146648 PMC5338029__F5 Syndrome of central hypothyroidism and macroorchidism: IGSF1 controls TRHR and FSHB expression by differential modulation of pituitary TGFB and Activin pathways ENSG00000105329 ENSG00000147255 ENSG00000174417 ENSG00000170893 ENSG00000134200 PMC5622428__F4 Network based on a restricted number of genes after selection of topological parameters ENSG00000198856 ENSG00000171791 ENSG00000112715 ENSG00000026103 PMC8297972__F1 Aspirin Actions in Treatment of NSAID-Exacerbated Respiratory Disease ENSG00000137033 ENSG00000171049 PMC4445728__F1 Development and in vivo function of TH9 cells ENSG00000138378 ENSG00000111537 ENSG00000134982 ENSG00000168610 PMC6710335__F8 The working model of Tpl2 in protecting against fulminant hepatitis ENSG00000081041 ENSG00000163739 ENSG00000166090 PMC6595474__F8 Summary of mechanisms by which exosomes from cyclic stretch-exposed PDL cells negatively regulate IL-1B production in macrophages ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC5711888__F3 A Network Model to Explore the Effect of the Micro-environment on Endothelial Cell Behavior during Angiogenesis ENSG00000137834 ENSG00000154764 ENSG00000165197 ENSG00000105329 ENSG00000291971 ENSG00000127528 ENSG00000168036 ENSG00000112715 ENSG00000168610 ENSG00000163217 ENSG00000170365 ENSG00000198435 ENSG00000150630 PMC5711888__F2 A Network Model to Explore the Effect of the Micro-environment on Endothelial Cell Behavior during Angiogenesis ENSG00000167601 ENSG00000165197 ENSG00000070831 ENSG00000134982 ENSG00000291971 ENSG00000198793 ENSG00000127528 ENSG00000137845 ENSG00000104332 ENSG00000112715 ENSG00000166068 ENSG00000125084 ENSG00000196712 ENSG00000137834 ENSG00000113240 ENSG00000148400 ENSG00000163217 ENSG00000066468 ENSG00000100592 ENSG00000198435 ENSG00000010810 ENSG00000175104 ENSG00000168646 ENSG00000103335 ENSG00000150630 PMC6343099__F2 Regulated signal pathways and transcription factors of NCX1 in digestive diseases ENSG00000144935 ENSG00000137672 PMC8967572__F4 Dietary Phytochemicals Targeting Nrf2 to Enhance the Radiosensitivity of Cancer ENSG00000149311 ENSG00000175054 ENSG00000143375 ENSG00000079999 PMC8602556__F1 Crosstalk Between ER Stress, Autophagy and Inflammation ENSG00000162711 ENSG00000183735 ENSG00000128272 ENSG00000144895 ENSG00000125538 ENSG00000169136 ENSG00000265972 ENSG00000127191 PMC2394752__F4 Contextual organization of the NFKB positive modulators ENSG00000145632 ENSG00000145687 ENSG00000110330 ENSG00000092445 ENSG00000117153 ENSG00000135451 ENSG00000122877 ENSG00000160710 ENSG00000150455 ENSG00000107537 ENSG00000170043 ENSG00000006327 ENSG00000134046 ENSG00000104497 ENSG00000100558 ENSG00000104689 ENSG00000230989 ENSG00000130876 ENSG00000226275 ENSG00000180855 ENSG00000130669 ENSG00000119125 ENSG00000125734 ENSG00000102962 ENSG00000128951 ENSG00000079482 ENSG00000120889 ENSG00000135341 ENSG00000185774 ENSG00000120539 ENSG00000137204 ENSG00000103490 ENSG00000108788 ENSG00000126458 ENSG00000121742 ENSG00000119965 ENSG00000104365 ENSG00000269335 ENSG00000004534 ENSG00000060558 ENSG00000168040 ENSG00000127191 ENSG00000006062 ENSG00000215788 ENSG00000221978 ENSG00000021300 ENSG00000149809 ENSG00000102898 ENSG00000028137 ENSG00000145349 ENSG00000141655 ENSG00000132341 PMC12027414__F6 Impact of NPC86 on insulin signaling and inflammatory pathways in adipose tissue ENSG00000104812 ENSG00000141349 ENSG00000130957 ENSG00000002330 ENSG00000198793 ENSG00000115904 ENSG00000169710 ENSG00000141564 ENSG00000169032 ENSG00000068976 ENSG00000004455 ENSG00000163558 ENSG00000167941 ENSG00000182473 ENSG00000165458 ENSG00000150907 ENSG00000068383 ENSG00000171105 ENSG00000125733 ENSG00000111713 ENSG00000160999 ENSG00000111725 ENSG00000187840 ENSG00000110395 ENSG00000079435 ENSG00000159399 ENSG00000067177 PMC6139039__F1 Stabilizing and destabilizing signals for Tregs ENSG00000111537 ENSG00000163599 ENSG00000049768 PMC8784108__F4 Insight into the symbiotic lifestyle of DPANN archaea revealed by cultivation and genome analyses ENSG00000106628 PMC10548218__F1 FGF effects in breast cancer cells ENSG00000070193 ENSG00000140285 ENSG00000102678 PMC4523312__F2 Protein interaction pathway produced by combining known protein–protein interactions from the literature ENSG00000002330 ENSG00000070831 ENSG00000198793 ENSG00000163914 ENSG00000169047 ENSG00000171791 ENSG00000168610 PMC7306315__F1 Iron homeostasis and signaling pathways involved in hepcidin regulation ENSG00000178752 ENSG00000105697 PMC5512429__F3 Cellular signaling pathways and transcriptional regulatory circuits mediating physiologic cardiac hypertrophic growth ENSG00000179862 ENSG00000124102 ENSG00000169047 ENSG00000106459 PMC9032101__F1 Importance of Endoplasmic Reticulum Stress as a Novel Antidepressant Drug Target and Its Potential Impact on CNS Disorders ENSG00000134109 ENSG00000128272 PMC3479160__F5 PPI subnetworks of the extended disease pathways ENSG00000019991 ENSG00000002330 ENSG00000138798 ENSG00000157240 ENSG00000145431 ENSG00000143801 ENSG00000132781 ENSG00000163251 ENSG00000113318 ENSG00000205155 ENSG00000125538 ENSG00000119912 ENSG00000282899 ENSG00000174804 ENSG00000159593 ENSG00000285246 ENSG00000197461 ENSG00000113905 ENSG00000177606 ENSG00000182240 ENSG00000115266 ENSG00000175899 ENSG00000188763 ENSG00000095002 ENSG00000114279 PMC8977417__F2 Biological Characteristics and Clinical Significance of Soluble PD-1/PD-L1 and Exosomal PD-L1 in Cancer ENSG00000040275 ENSG00000198793 PMC7954751__F9 Hormonal regulation of human DNA methyl transferases ENSG00000152266 ENSG00000117525 ENSG00000291971 ENSG00000088305 ENSG00000145321 PMC6745489__F5 Rectal cancer sub-clones respond differentially to neoadjuvant therapy ENSG00000070182 ENSG00000134982 ENSG00000115350 ENSG00000108561 ENSG00000070444 ENSG00000116670 ENSG00000143379 ENSG00000197386 ENSG00000197858 ENSG00000205937 ENSG00000138741 ENSG00000285049 ENSG00000155657 ENSG00000151882 ENSG00000138347 ENSG00000064393 ENSG00000183684 ENSG00000072315 ENSG00000124193 ENSG00000104408 ENSG00000186716 ENSG00000124155 ENSG00000131018 ENSG00000122008 ENSG00000135250 PMC6128733__F1 Neurotrophin Trafficking via Trk Receptors ENSG00000143553 ENSG00000291761 PMC3902842__F3 Molecular mechanisms involved in leptin receptor signaling in the hypothalamus ENSG00000168610 PMC8261751__F2 Coronavirus disease and the cardiovascular system: a narrative review of the mechanisms of injury and management implications ENSG00000130234 PMC3234335__F1 Hereditary Hemochromatosis and Transferrin Receptor 2 ENSG00000170365 ENSG00000010704 ENSG00000106327 ENSG00000105697 ENSG00000168610 PMC12071082__F3 Therapies targeting RASGAPs in urological cancers ENSG00000149311 ENSG00000136848 PMC6128733__F2 Neurotrophin Trafficking via Trk Receptors ENSG00000041353 ENSG00000130294 PMC11007187__F4 Decoding the secrets of longevity: unraveling nutraceutical and miRNA-Mediated aging pathways and therapeutic strategies ENSG00000198793 ENSG00000096717 PMC11007187__F1 Decoding the secrets of longevity: unraveling nutraceutical and miRNA-Mediated aging pathways and therapeutic strategies ENSG00000092847 ENSG00000113360 ENSG00000134698 ENSG00000123908 ENSG00000132341 PMC8615487__F2 An Epigenetic Insight into NLRP3 Inflammasome Activation in Inflammation-Related Processes ENSG00000141867 ENSG00000162711 ENSG00000163435 ENSG00000173039 ENSG00000172936 ENSG00000007047 ENSG00000265972 ENSG00000100219 ENSG00000175567 ENSG00000142082 ENSG00000168610 ENSG00000283100 PMC4033011__F2 Possible pathways for LRP1-mediated AB uptake PMC4650429__F1 During normal cellular conditions, BRD4 recognizes acetylated lysine residues on histones and recruits positive transcription elongation factor b (P-TEFb) to promote transcriptional elongation by RNA polymerase II of key oncogenic drivers such as MYC ENSG00000141867 ENSG00000136997 ENSG00000168036 PMC7609776__F4 KEGG AD pathway including Cd-associated transcripts in males ENSG00000132906 ENSG00000291983 ENSG00000142192 ENSG00000002330 ENSG00000120868 ENSG00000168040 ENSG00000119912 ENSG00000164305 PMC11860889__F1 Activation or silencing of WNT signaling pathway in the presence or absence of WNT ligands 1 ENSG00000281324 ENSG00000162337 ENSG00000122691 ENSG00000134982 ENSG00000168036 PMC7783665__F1 Calcineurin-NFAT pathway for expression of cytokines and cell membrane proteins ENSG00000197943 PMC6412382__F1 Mammalian target of rapamycin (mTOR) regulatory network ENSG00000169047 ENSG00000198793 ENSG00000155792 ENSG00000108443 ENSG00000164327 ENSG00000167965 ENSG00000167371 ENSG00000103257 ENSG00000121879 ENSG00000083750 ENSG00000101407 ENSG00000106070 ENSG00000118515 ENSG00000239282 ENSG00000177169 ENSG00000104365 ENSG00000142192 ENSG00000177058 ENSG00000173156 ENSG00000155876 ENSG00000217128 ENSG00000213341 ENSG00000025039 ENSG00000187840 ENSG00000162409 ENSG00000145979 ENSG00000204673 ENSG00000134324 ENSG00000010030 PMC7783665__F4 Calcineurin activation by cAMP/PKA and interaction with CaM for cell secretion ENSG00000182718 ENSG00000197747 ENSG00000110799 ENSG00000001626 PMC3562392__F3 Cytoscape diagram of the functional interaction network representing proteins modulation in Pt1 interstitial fluid ENSG00000070182 ENSG00000197879 ENSG00000130332 ENSG00000149100 ENSG00000163554 ENSG00000171560 ENSG00000089820 ENSG00000106927 ENSG00000163631 PMC4997298__F6 Upstream regulatory analysis of weight-loss–associated genes identified strong C/EBPA activation ENSG00000131473 ENSG00000245848 ENSG00000118898 ENSG00000099194 ENSG00000137267 PMC4200329__F4 Schematic representation of the amniotic fluid eicosanoid profile PMC12012437__F1 S100P signaling pathways associated with proliferation, apoptosis, migration, invasion and EMT in tumors ENSG00000128272 ENSG00000125398 ENSG00000138083 ENSG00000115415 ENSG00000163993 ENSG00000168036 ENSG00000265972 ENSG00000079999 PMC10740567__F1 Signaling pathways involved in the inhibition of apoptosis by Apicomplexan protozoa ENSG00000102871 ENSG00000120868 ENSG00000168040 ENSG00000127191 ENSG00000168610 ENSG00000146648 PMC12012437__F2 S100P signaling pathways associated with angiogenesis, cell cycle and drug resistance in tumors ENSG00000110031 ENSG00000160182 ENSG00000163993 PMC5531310__F3 Glycolysis is downregulated in idiopathic pulmonary fibrosis (IPF) lungs, with possible shuttling of intermediates to the sorbitol and pentose phosphate pathways ENSG00000141349 ENSG00000125520 PMC5531310__F2 Arginine metabolism is increased in the idiopathic pulmonary fibrosis (IPF) lung ENSG00000081181 ENSG00000118520 PMC5531310__F1 Downregulated sphingolipid metabolism in idiopathic pulmonary fibrosis (IPF) lungs ENSG00000143753 ENSG00000292130 ENSG00000170989 ENSG00000078124 ENSG00000125910 PMC8537973__F10 Network Pharmacology of Red Ginseng (Part I): Effects of Ginsenoside Rg5 at Physiological and Sub-Physiological Concentrations ENSG00000087245 ENSG00000180182 ENSG00000133056 ENSG00000130414 ENSG00000105647 ENSG00000105639 ENSG00000108510 ENSG00000145391 ENSG00000177565 ENSG00000106459 ENSG00000145431 ENSG00000143252 ENSG00000125249 ENSG00000106617 ENSG00000128272 ENSG00000077150 ENSG00000177606 ENSG00000092841 ENSG00000185591 ENSG00000114315 ENSG00000132535 PMC2268699__F2 FGF canonical signalling pathway ENSG00000162889 ENSG00000168610 PMC2268699__F1 p38 MAPK canonical signalling pathway ENSG00000162889 ENSG00000115415 ENSG00000102871 ENSG00000168040 ENSG00000175104 ENSG00000127191 ENSG00000114738 ENSG00000026103 PMC7112453__F1 NAD+ metabolism pathways in mammals ENSG00000105835 ENSG00000123572 ENSG00000278488 ENSG00000157064 ENSG00000008130 PMC8939237__F1 Regulatory Pathways Governing Metabolic Control of Puberty Discerned from Rodent, Nonhuman Primate, and Human Studies ENSG00000129214 ENSG00000198793 ENSG00000198576 ENSG00000074266 ENSG00000096717 PMC3783495__F7 Antagonism of Betulinic Acid on LPS-Mediated Inhibition of ABCA1 and Cholesterol Efflux through Inhibiting Nuclear Factor-kappaB Signaling Pathway and miR-33 Expression ENSG00000172936 ENSG00000136869 PMC3901678__F6 Mining Gene Expression Data for Pollutants (Dioxin, Toluene, Formaldehyde) and Low Dose of Gamma-Irradiation ENSG00000015285 ENSG00000080166 ENSG00000102003 PMC10478265__F2 The cGAS-STING pathway in radiotherapy for non-small cell lung cancer ENSG00000169245 ENSG00000164430 ENSG00000138755 PMC10478265__F1 The cGAS-STING pathway in radiotherapy for non-small cell lung cancer ENSG00000164430 PMC5915650__F7 Proposed mechanotransduction mechanism ENSG00000163914 ENSG00000168036 PMC6562751__F2 Signaling Pathways and Cellular Processes Regulated by Keratins, Vimentin, and Nestin ENSG00000167601 ENSG00000162711 ENSG00000165119 ENSG00000102871 ENSG00000291971 ENSG00000198793 ENSG00000168036 ENSG00000168610 ENSG00000186810 ENSG00000160224 ENSG00000185591 ENSG00000077782 ENSG00000146648 PMC5768180__F7 Interferon regulatory factor 5 regulates B cell proliferation and cell cycle ENSG00000170027 ENSG00000134982 ENSG00000073111 ENSG00000108852 ENSG00000117399 ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000132646 ENSG00000061273 ENSG00000123374 ENSG00000080839 ENSG00000253729 ENSG00000282899 PMC8235370__F1 Coronavirus RNA-Processing Enzymes in Innate Immune Evasion ENSG00000213928 ENSG00000115415 PMC3714203__F2 DR4 and DR5 Agonistic mAb-induced Apoptosis: Regulation of TRAIL/Apo2L Resistance by HDACi ENSG00000100290 ENSG00000002330 PMC8705212__F4 Camptothecin Encapsulated in Beta-Cyclodextrin-EDTA-Fe3O4 Nanoparticles Induce Metabolic Reprogramming Repair in HT29 Cancer Cells through Epigenetic Modulation: A Bioinformatics Approach ENSG00000128050 ENSG00000131473 ENSG00000078237 PMC8918554__F9 The functions of NR2F1-AS1 in pancreatic cancer ENSG00000175745 ENSG00000198793 PMC10540332__F7 Combined transcriptomic and metabolomic analysis of alginate oligosaccharides alleviating salt stress in rice seedlings ENSG00000002549 PMC3627976__F1 The polyamine pathway ENSG00000123505 ENSG00000116649 ENSG00000102172 PMC4892997__F1 Antiviral Innate Immunity through the lens of Systems Biology ENSG00000213928 ENSG00000167207 ENSG00000185436 ENSG00000163565 ENSG00000185745 ENSG00000174953 ENSG00000276561 ENSG00000142166 ENSG00000184979 ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000136869 ENSG00000107201 ENSG00000135828 PMC8297769__F7 Summary and model of synergistic myocardial infarct size reduction by IPC in cardiac-specific SOCS3-deficient mice ENSG00000168610 PMC12092085__F4 Biodegradable magnesium-based implants inhibit osteoclast differentiation through multiple mechanisms ENSG00000082512 ENSG00000175104 ENSG00000127191 ENSG00000131196 PMC3619548__F1 Schematic summary of the most common mutations found in melanoma patients ENSG00000157764 PMC6425966__F3 Examples of prediction by eQTL signal convergence across distinct chromosomes PMC12092085__F8 PTH reduces the binding of RANKL to OPG by inhibiting the secretion of OPG from osteoblasts and acting on the cAMP-PKA-CREB and PP1/PP2A-CRTC3 pathways ENSG00000152266 ENSG00000160584 ENSG00000177606 ENSG00000170145 ENSG00000140577 PMC12092085__F1 Magnesium promotes osteogenesis ENSG00000178860 ENSG00000092439 ENSG00000291837 PMC8394846__F1 NFKB in Ageing and Age-Related Diseases: Lessons from Genetically Modified Mouse Models ENSG00000104856 ENSG00000162924 ENSG00000083799 PMC3410583__F3 Pathways of autophagy induction by hypoxia and mutant RAS ENSG00000128272 ENSG00000198793 ENSG00000057663 PMC3460904__F7 Transcriptional Targets of Mutant FOXL2 in Granulosa Cell Tumours ENSG00000137834 ENSG00000198742 ENSG00000156574 ENSG00000134363 ENSG00000283060 ENSG00000125968 PMC3509664__F3 PKR and the Insulin signaling pathway ENSG00000169047 ENSG00000198793 PMC5382109__F6 Therapeutic targets in B cell lymphoma of NFKB activation ENSG00000007312 ENSG00000186716 ENSG00000172936 ENSG00000010671 PMC3928598__F1 Protein O-linked ß-N-acetylglucosamine: A novel effector of cardiomyocyte metabolism and function ENSG00000147162 ENSG00000198408 PMC4589285__F11 Hemorrhage Exacerbates Radiation Effects on Survival, Leukocytopenia, Thrombopenia, Erythropenia, Bone Marrow Cell Depletion and Hematopoiesis, and Inflammation-Associated microRNAs Expression in Kidney ENSG00000177606 ENSG00000136869 ENSG00000168040 ENSG00000146648 ENSG00000204217 PMC3509664__F8 PKR, ISG15 as modulators of IFN induction during HCV infection ENSG00000088888 ENSG00000187608 ENSG00000144895 ENSG00000131323 ENSG00000121060 PMC5382109__F3 Apoptotic pathways of NFKB: TRAIL mediating the extrinsic pathway and p53 mediating the intrinsic pathway ENSG00000173039 ENSG00000120868 PMC3509664__F7 HCV and induction of the innate immune response ENSG00000088888 ENSG00000121060 ENSG00000164342 PMC5382109__F2 Activation modes of NFKB in the pathogenesis of B cell lymphoma ENSG00000177455 ENSG00000095585 ENSG00000105369 ENSG00000198286 PMC5382109__F5 Extrinsic and intrinsic signaling of BCR signaling activates NFKB in B-cell malignancies ENSG00000104856 ENSG00000186716 ENSG00000172936 ENSG00000198286 PMC5530905__F1 Action of PPARG ligands and p38 MAPK on transforming growth factor (TGF)B1–induced Beta-catenin signaling in corneal fibroblasts ENSG00000134982 PMC5901476__F1 Mineral and bone disorders in chronic kidney disease (CKD) ENSG00000118972 ENSG00000152266 PMC3460238__F1B Central role of AP convertase in complement activation ENSG00000197971 ENSG00000196352 ENSG00000117335 PMC5382109__F1 Canonical and non-canonical NFKB pathways ENSG00000104856 ENSG00000007312 ENSG00000173039 ENSG00000162924 ENSG00000175104 ENSG00000010671 PMC3686839__F2 Molecular Pathways: Extracting Medical Knowledge from High Throughput Genomic Data ENSG00000177455 ENSG00000100906 ENSG00000177606 ENSG00000136997 ENSG00000095015 ENSG00000065559 ENSG00000121879 PMC5901476__F3 Proposed mechanisms by which PTH activates Wnt/Beta-catenin pathway in osteoblasts and osteocytes to modulate bone turnover ENSG00000152266 ENSG00000168036 PMC7176583__F1 Gastric cancer: genome damaged by bugs ENSG00000088826 ENSG00000291971 ENSG00000134982 ENSG00000125538 ENSG00000168036 ENSG00000175104 ENSG00000106100 ENSG00000168610 PMC3038050__F1 Mechanisms by which CD44 can modulate cell death ENSG00000122882 ENSG00000198793 ENSG00000026508 ENSG00000168040 ENSG00000026103 PMC5320748__F1 Similar signaling cascades involved with neuroprotection for insulin-like peptides and sex hormones ENSG00000002330 ENSG00000169047 ENSG00000198793 ENSG00000140443 PMC10967781__F2 Insulin-like Growth Factor-1 Receptor in Tobacco Smoking-Associated Lung Cancer Development ENSG00000002330 ENSG00000115457 ENSG00000167779 ENSG00000198793 ENSG00000146678 ENSG00000171791 ENSG00000115461 ENSG00000140443 PMC10967781__F1 Functional connections between the IR and IGF-R signaling axis ENSG00000197081 ENSG00000140443 PMC8626172__F8 Network Pharmacology‐Based Study on the Active Component and Mechanism of the Anti-Gastric-Cancer Effect of Herba Sarcandrae ENSG00000081041 ENSG00000050628 ENSG00000007908 ENSG00000145386 ENSG00000073756 ENSG00000169245 ENSG00000108691 ENSG00000134057 ENSG00000136997 ENSG00000166501 ENSG00000291748 ENSG00000100985 ENSG00000108821 ENSG00000162692 PMC3568185__F1 PGE2biosynthetic pathway PMC4307032__F2 Signaling Molecules: Hydrogen Sulfide and Polysulfide PMC6258792__F4 CREB1 signaling is predicted to be altered by ID ENSG00000172216 ENSG00000159388 ENSG00000122877 ENSG00000198576 ENSG00000101327 ENSG00000073756 PMC6282071__F3 Increased P2X4R expression after nerve injury via the actions of fibronectin in activated microglia ENSG00000108691 ENSG00000140968 ENSG00000121807 ENSG00000117322 PMC3259815__F8 Signaling through PAK in the hyperosmotic response pathway ENSG00000070831 PMC1892100__F1 Image showing the human insulin signaling pathway from BioCarta ENSG00000033327 ENSG00000167941 ENSG00000169047 PMC3180377__F9 Toll-Like Receptor 2 Pathway Regulates the Ppargc1a/b Metabolic Co-Activators in Mice with Staphylococcal aureus Sepsis ENSG00000109819 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC7600476__F3 The major cell signaling pathways by resveratrol and/or curcumin in melanoma ENSG00000157764 ENSG00000198793 ENSG00000168036 ENSG00000171791 ENSG00000168610 PMC9587090__F2 Cellular senescence and acute kidney injury ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC8931477__F1 Natural Products Against Renal Fibrosis via Modulation of SUMOylation ENSG00000079387 ENSG00000112701 ENSG00000196591 ENSG00000168036 ENSG00000188612 ENSG00000177688 ENSG00000184900 PMC5863447__F2 Hierarchical clustering analysis of all differentially expressed proteins (DEPs) (812 proteins at p ≤ 0.05 with ≥ 2 unique peptides) ENSG00000189058 ENSG00000185634 ENSG00000109758 ENSG00000111713 ENSG00000169710 ENSG00000104918 ENSG00000079435 PMC7868824__F45 Targeting NFKB mediated cell signaling pathway and inflammatory mediators by 1,2-diazole in A549 cells in vitro ENSG00000136869 ENSG00000146648 PMC3116111__F1 Graphical representation of the candidate genes involved in the pharmacodynamics of doxorubicin in a stylized cancer cell ENSG00000104884 ENSG00000017797 ENSG00000109320 ENSG00000131747 ENSG00000103222 ENSG00000118777 ENSG00000095002 ENSG00000023839 ENSG00000158125 PMC8563895__F7 B2-adrenergic receptor regulates ER-mitochondria contacts ENSG00000203485 ENSG00000070831 ENSG00000156026 PMC5969912__F3 Once and only once: mechanisms of centriole duplication and their deregulation in disease ENSG00000048028 ENSG00000150457 PMC8157545__F1 Efficacy of BRAF and MEK Inhibition in Patients with BRAF-Mutant Advanced Melanoma and Germline CDKN2A Pathogenic Variants ENSG00000157764 ENSG00000135446 ENSG00000105810 PMC11915076__F1 Oncogenic and tumor-suppressive roles of Lipocalin 2 (LCN2) in tumor progression ENSG00000148346 ENSG00000128272 ENSG00000170989 ENSG00000168610 PMC3827506__F5 Signaling by innate immune receptors ENSG00000162711 ENSG00000167207 ENSG00000172936 ENSG00000175104 PMC3217176__F3 Targeting the PI3K/AKT/mTOR pathway ENSG00000002330 PMC5280876__F3 Mesenchymal Stem Cell Derived Secretome and Extracellular Vesicles for Acute Lung Injury and Other Inflammatory Lung Diseases ENSG00000162692 ENSG00000140443 PMC5501684__F6 Effect of praziquantel on the differential expression of mouse hepatic genes and parasite ATP binding cassette transporter gene family members during Schistosoma mansoni infection ENSG00000087245 ENSG00000163235 PMC5207462__F2 Insulin signaling pathway ENSG00000124102 PMC5501684__F5 Effect of praziquantel on the differential expression of mouse hepatic genes and parasite ATP binding cassette transporter gene family members during Schistosoma mansoni infection ENSG00000150782 ENSG00000117091 ENSG00000106603 ENSG00000113520 PMC5501684__F4 Effect of praziquantel on the differential expression of mouse hepatic genes and parasite ATP binding cassette transporter gene family members during Schistosoma mansoni infection ENSG00000158825 ENSG00000113520 ENSG00000084774 PMC4350910__F3 Pathway for the synthesis of the endocannabinoids AEA and 2-AG ENSG00000117480 ENSG00000196689 PMC3722525__F7 Antigen processing and presentation pathway and the cell cycle pathway ENSG00000049323 ENSG00000019582 ENSG00000170365 ENSG00000137834 ENSG00000111537 ENSG00000134982 ENSG00000198742 ENSG00000183691 ENSG00000204217 ENSG00000117399 PMC5501684__F7 Effect of praziquantel on the differential expression of mouse hepatic genes and parasite ATP binding cassette transporter gene family members during Schistosoma mansoni infection ENSG00000087245 ENSG00000163235 PMC2561291__F1 Signaling Flux Redistribution at Toll-Like Receptor Pathway Junctions ENSG00000169245 ENSG00000183735 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC7941218__F3 GDF‐5 signalling pathway and regulation of GDF‐5 expression ENSG00000178860 ENSG00000139219 ENSG00000134982 ENSG00000176887 ENSG00000157766 ENSG00000168036 ENSG00000104447 PMC5215890__F6 The p53-like Protein CEP-1 Is Required for Meiotic Fidelity in C. elegans ENSG00000204335 ENSG00000217236 ENSG00000291837 ENSG00000185591 ENSG00000167182 ENSG00000054796 PMC7278922__F2 Two distinct Fe/S cluster biosynthetic pathways exist in mitochondria (mitochondrial NFS pathway, left) and plastid (plastidial SUF pathway, right) in Arabidopsis ENSG00000100209 ENSG00000169599 PMC2561291__F5 Signaling Flux Redistribution at Toll-Like Receptor Pathway Junctions ENSG00000183735 ENSG00000172936 ENSG00000175104 PMC4449696__F2 Retinoid metabolism and the structure of retinoid receptors ENSG00000138207 ENSG00000277273 PMC4760086__F2 Inflammation in SCD ENSG00000169245 ENSG00000163739 ENSG00000138755 ENSG00000189403 ENSG00000169429 ENSG00000136869 ENSG00000162692 PMC8009949__F6 Part of C21-steroird biosynthesis pathway ENSG00000203859 PMC4486424__F6 Ingenuity Pathways Analysis summary ENSG00000110711 ENSG00000105329 ENSG00000078900 ENSG00000138798 ENSG00000064012 ENSG00000143995 PMC11955613__F5 Pyroptotic osteocytes promote osteoclastogenesis ENSG00000278718 ENSG00000162711 ENSG00000137757 ENSG00000196954 PMC4980649__F1 Main WNT/Beta-catenin pathway involved in cancer and stem cells ENSG00000071564 ENSG00000134982 ENSG00000168036 ENSG00000119715 PMC11955613__F2 Apoptotic and necrotic osteocytes promote osteoclastogenesis ENSG00000112715 ENSG00000164305 PMC9319258__F5 Possible Cause for the Differential Expression of a Subset of miRNAs in Mesenchymal Stem Cells Derived from Myometrium and Leiomyoma ENSG00000049323 ENSG00000094880 ENSG00000005339 ENSG00000142798 ENSG00000170027 ENSG00000134308 ENSG00000158195 ENSG00000156574 ENSG00000205250 ENSG00000101266 ENSG00000135341 ENSG00000124762 ENSG00000188153 ENSG00000041982 ENSG00000118785 ENSG00000134057 ENSG00000136997 ENSG00000291748 ENSG00000026508 ENSG00000185591 ENSG00000172752 ENSG00000080839 ENSG00000253729 PMC11955613__F4 Ferroptotic osteocytes promote osteoclastogenesis ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000111684 PMC4617705__F4 Effects of CsA on the expression of genes involved in endoplasmic reticulum stress and FXR-regulated pathways in WT-PCLS and FXRKO-PCLS ENSG00000105894 ENSG00000102977 PMC7299245__F1 Targets of new therapeutic options in beta-thalassemia ENSG00000170365 ENSG00000010704 ENSG00000106327 ENSG00000178752 ENSG00000105697 ENSG00000135414 ENSG00000130283 ENSG00000266524 ENSG00000184344 ENSG00000168610 PMC7240957__F8 Mechanism of cytochrome P450 (CYP450)-dependent metabolism of polyunsaturated omega-6 and omega-3 fatty acids involved in CKD progression ENSG00000105131 ENSG00000120915 ENSG00000130649 PMC5846367__F2 Interplay between immune system and gut microbiota in homeostasis, tolerance, and inflammation ENSG00000111537 ENSG00000137033 ENSG00000134982 ENSG00000145777 PMC3773992__F2 Crosstalk between hedgehog signaling, Wnt/Beta-catenin signaling, notch signaling, and phosphoinositide 3 (PI3)-kinase/Akt pathway and targeting by norcantharidin (NCTD) ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000050165 ENSG00000184207 ENSG00000184916 ENSG00000128602 PMC7991087__F5 Summarizing Figure ENSG00000113161 ENSG00000136869 ENSG00000198911 PMC6290143__F2 Role of the APC tumor suppressor gene in signaling expression of genes regulating the polyamine pathway ENSG00000134982 ENSG00000136997 ENSG00000078098 PMC6307803__F6 The model of miR‐520b regulating NSCLC tumourigenesis ENSG00000106571 ENSG00000121067 PMC7932307__F2 Nucleic acid immunotherapeutics that can activate the cGAS-STING signaling pathway ENSG00000164430 PMC5454811__F4 Schematic diagrams of (A) the BR biosynthesis pathway, (B) BR signal transduction pathway, and (C) auxin signaling transduction pathway ENSG00000108582 ENSG00000110934 ENSG00000062485 PMC4031983__F8 MiRNA dependent regulation of DSB repair during cell cycle ENSG00000012048 ENSG00000154059 ENSG00000051180 ENSG00000139618 PMC3996470__F1 Receptor-mediated endocytic pathway in nonpolarized mammalian cells ENSG00000130164 ENSG00000119655 ENSG00000141458 PMC7244267__F4 Significantly enhancing production of trans-4-hydroxy-l-proline by integrated system engineering in Escherichia coli ENSG00000122966 ENSG00000172005 PMC8882646__F1 Interaction of Mycobacteria With Host Cell Inflammasomes ENSG00000278718 ENSG00000131669 ENSG00000162711 ENSG00000163568 ENSG00000189403 PMC6541953__F2 Anti-inflammatory and antioxidant mechanisms of neuroprotection and neuronal function by ursolic acid ENSG00000181019 ENSG00000198793 ENSG00000167419 PMC3021128__F7 Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7 ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000166508 PMC2106369__F1 Schematic overview of the RANK-NFKB signalling pathway ENSG00000165280 ENSG00000175104 PMC4737002__F1 Regulation of interconnected stem cell signaling nodes by the AR ENSG00000168610 ENSG00000136826 PMC6536593__F5 Implication of hexosamine biosynthetic pathway on the NLRP3 inflammasome ENSG00000162711 ENSG00000147162 ENSG00000198408 ENSG00000125538 ENSG00000265972 PMC3694812__F1 Towards Systematic Discovery of Signaling Networks in Budding Yeast Filamentous Growth Stress Response Using Interventional Phosphorylation Data ENSG00000196511 ENSG00000070831 ENSG00000158458 PMC3694812__F4 Towards Systematic Discovery of Signaling Networks in Budding Yeast Filamentous Growth Stress Response Using Interventional Phosphorylation Data ENSG00000196511 ENSG00000070831 ENSG00000158458 ENSG00000140416 PMC7497261__F1 Different inflammasome complexes: (From left to right) Engagement of different TLR receptors leads to activation of IKKs, which in turn results in activation of NF‐KB signaling ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000091592 ENSG00000189403 ENSG00000091106 ENSG00000123143 ENSG00000142002 ENSG00000065243 PMC3419137__F3 Targets of the tumor suppressor gene miR-200 in regulation of the epithelial-mesenchymal transition in cancer ENSG00000064601 ENSG00000101160 ENSG00000170558 ENSG00000113140 ENSG00000137563 ENSG00000116962 ENSG00000148848 ENSG00000103811 ENSG00000143537 ENSG00000142910 ENSG00000159674 ENSG00000108679 ENSG00000166106 PMC9134136__F2 Ductular reaction in non-alcoholic steatohepatitis ENSG00000019991 ENSG00000106571 ENSG00000168036 ENSG00000150457 ENSG00000128602 ENSG00000131023 PMC4698100__F8 Regulatory functions of STAT3 in cardiac Beta-adrenergic functions ENSG00000196557 ENSG00000291971 ENSG00000043591 ENSG00000168610 PMC4850140__F1 Tested Wnt-related genes and proteins and their functions in the canonical Wnt signaling pathway are shown here ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC8273435__F4 The F-BAR Family Member PSTPIP2 in Autoinflammatory Diseases ENSG00000140368 PMC3585432__F1 The Drosophila Hippo pathway ENSG00000180210 ENSG00000126016 ENSG00000139926 ENSG00000150457 PMC4669899__F2 Simplified outline of Insulin and AA/TOR signaling pathways PMC3515332__F1 Class I PI3K/Akt/mTOR axis pathway ENSG00000002330 ENSG00000150907 ENSG00000169047 ENSG00000164327 PMC5475222__F2 Secreted T ENSG00000071655 ENSG00000081041 ENSG00000115415 ENSG00000164615 ENSG00000196839 ENSG00000175104 PMC5548997__F7 Involvement of BPA, BPS or BPF in the proliferation, EMT, and migration of MCF-7 CV cells via ER-dependent pathway ENSG00000170558 PMC12121119__F3 Bridging role of hepatokines in AD and metabolic disorders ENSG00000111537 ENSG00000105550 ENSG00000129214 ENSG00000167468 ENSG00000250722 ENSG00000136869 ENSG00000132855 PMC6540965__F2 Relationship between middle-age obesity, glutamate excitotoxicity and increased risk of Alzheimer’s disease ENSG00000198793 ENSG00000168610 PMC8704679__F2 JAK-STAT Pathway: A Novel Target to Tackle Viral Infections ENSG00000039537 ENSG00000213928 PMC7941705__F2 Anesthetic affect pro- and anti-cancer miRNA expressions leading to cancer biology changes ENSG00000087245 ENSG00000145321 ENSG00000100985 PMC9186411__F1 Dysregulation of the cGAS-STING Pathway in Monogenic Autoinflammation and Lupus ENSG00000162711 ENSG00000164430 ENSG00000173638 PMC8704679__F1 JAK-STAT Pathway: A Novel Target to Tackle Viral Infections ENSG00000183735 ENSG00000088888 PMC4363231__F1 Potential canonical WNT signaling pathway- Resting state (a): SFRP4 binds free WNT molecules in the extracellular space and DKK binds the LRP co-receptor ENSG00000169218 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000106483 PMC9256749__F4 Piezo1 channel promotes the tumorigenesis of prostate through the Akt/mTOR pathway (adapted from 111) ENSG00000135446 ENSG00000198793 ENSG00000103335 PMC6737422__F1 SCD-associated oxidative stress pathways and antioxidant systems ENSG00000182511 ENSG00000086991 ENSG00000136869 PMC5662719__F6 Schematic working hypothesis ENSG00000162711 ENSG00000164056 ENSG00000130234 ENSG00000125538 PMC7567162__F7 Tripterygium ingredients could inhibit multiple pathways, such as the NFKB pathway, JAK-STAT pathway, and PI3K-mTOR pathway, to regulate the hyperactive as well as pathogenicity biological functions in a various type of cells ( to ) ENSG00000134982 ENSG00000125538 PMC6534162__F2 Stimulating Cardiogenesis as a Treatment for Heart Failure ENSG00000145386 PMC11842143__F1 Developmental signaling pathways regulating osteoblast differentiation ENSG00000170365 ENSG00000281324 ENSG00000125398 ENSG00000168214 ENSG00000162337 ENSG00000168036 ENSG00000128602 PMC4292999__F5 Co-expression of the Wnt signaling pathway with CITED2 in spondyloarthritis (SpA) ENSG00000169071 ENSG00000174804 ENSG00000169884 ENSG00000125084 PMC6988322__F5 SMARCD1 nearest-neighbor adjacency subnetwork with the glucocorticoid receptor response pathway ENSG00000066117 ENSG00000005339 ENSG00000118515 ENSG00000139613 ENSG00000127616 PMC5733726__F1 Inborn errors of immunity underlying fungal diseases in otherwise healthy individuals ENSG00000162594 ENSG00000187796 ENSG00000115415 ENSG00000163739 ENSG00000125538 ENSG00000168610 ENSG00000163702 PMC9641109__F7 Identification of candidate hub genes correlated with the pathogenesis, diagnosis, and prognosis of prostate cancer by integrated bioinformatics analysis ENSG00000107562 ENSG00000131781 ENSG00000118971 ENSG00000124212 ENSG00000112715 ENSG00000138356 ENSG00000145431 ENSG00000185518 ENSG00000105664 ENSG00000196549 ENSG00000095303 ENSG00000197467 ENSG00000145936 ENSG00000121361 ENSG00000197565 ENSG00000122786 ENSG00000159899 ENSG00000143933 ENSG00000167641 ENSG00000073756 ENSG00000211445 ENSG00000139219 ENSG00000108691 ENSG00000113296 ENSG00000171848 ENSG00000136160 ENSG00000154188 ENSG00000049089 PMC3078731__F3 Central prostate cancer-related processes and their miRNA-mediated regulation ENSG00000163914 PMC6835793__F1 The CD40-ATP-P2X7pathway links cellular responses in Müller cells with the induction of inflammatory responses in bystander microglia/macrophages in DR ENSG00000108691 ENSG00000125538 ENSG00000007171 PMC8300779__F2 Nrf2 in Cancer, Detoxifying Enzymes and Cell Death Programs ENSG00000100387 ENSG00000079999 PMC5542024__F9 Graphical Summary ENSG00000076928 PMC2259254__F2 Balance between muscle hypertrophy and atrophy depends on whether protein synthesis is more active than degradation or vice versa ENSG00000198793 PMC8766493__F7 Fatty Acid Signaling in Islet Beta-Cell Adaptation to Normal Pregnancy ENSG00000042832 ENSG00000126266 ENSG00000173599 PMC6966572__F2 PARP inhibitors in combination with other therapeutics ENSG00000169245 ENSG00000183735 ENSG00000134982 ENSG00000138755 ENSG00000126353 PMC12162639__F1 NLRP3 inflammasome signaling pathway ENSG00000278718 ENSG00000162711 ENSG00000172936 PMC7594482__F1 Osteogenesis regulating signaling pathways ENSG00000152266 ENSG00000066468 ENSG00000110395 ENSG00000169071 ENSG00000150907 ENSG00000163914 ENSG00000165879 ENSG00000124766 ENSG00000168036 ENSG00000128602 ENSG00000077782 PMC6720185__F1 Stress and depression drive an increase in corticotropin releasing factor (CRF) that activates mucosal mast cells and leads to an increase in gut permeability, coupled to gut dysbiosis and decreased butyrate production ENSG00000165841 ENSG00000169860 ENSG00000106546 PMC2858440__F5 Four flux sensors of the in silico cell ENSG00000095321 ENSG00000150787 ENSG00000078098 ENSG00000132693 PMC12162639__F2 Inflammatory regulation in the process of venous thrombosis formation ENSG00000110799 ENSG00000162692 PMC5945810__F2 Protein regulation of the TLR2/1 signaling pathway ENSG00000204977 ENSG00000125538 ENSG00000134070 ENSG00000172936 ENSG00000083799 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC7140927__F1 Sensing mechanisms for abiotic stress in plants ENSG00000105722 ENSG00000164151 ENSG00000122877 ENSG00000115904 ENSG00000100485 PMC7080653__F1 T1DM candidate genes acting at the beta-cell level mainly play a role in three pathways (): (1) Regulate the innate immune response and pathways important for antiviral activity, such as the type 1 IFN signaling pathway (IFIH1, TYK2, PTPN2) ENSG00000103811 ENSG00000213928 ENSG00000105397 ENSG00000065361 ENSG00000118503 ENSG00000115415 ENSG00000107249 ENSG00000038532 ENSG00000112182 PMC7848346__F1 Traditional (right hand side, orange background) and alternative (left hand side, blue background) renin‐angiotensin‐aldosterone system pathway ENSG00000112977 ENSG00000130234 PMC3245020__F3 Disease/drug mapping is the process to map all known disease genes (pink) and all known drug targets (light blue) against all KEGG pathway maps ENSG00000142192 ENSG00000002330 ENSG00000168040 ENSG00000119912 ENSG00000164305 PMC7048131__F3 Advances of the STAT3 signaling pathways involving breast cancer proliferation and apoptosis ENSG00000106785 ENSG00000275385 ENSG00000138798 ENSG00000112561 ENSG00000143499 ENSG00000168610 ENSG00000146648 ENSG00000205683 PMC8282123__F1 Endocrine Influence on Cardiac Metabolism in Development and Regeneration ENSG00000145321 PMC7048131__F2 Advances of the STAT3 signaling pathways involved in breast cancer progression ENSG00000094631 ENSG00000099985 ENSG00000138798 ENSG00000143499 ENSG00000168610 ENSG00000146648 PMC4264574__F1 TLR4 signaling cascade ENSG00000170458 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000276561 PMC3012138__F3 A network of hits highly enriched in cell cycle-related genes ENSG00000135549 ENSG00000110244 ENSG00000134982 ENSG00000284161 ENSG00000101306 ENSG00000111816 ENSG00000175054 ENSG00000109163 ENSG00000133107 ENSG00000136267 ENSG00000071082 ENSG00000112655 ENSG00000132341 PMC7048131__F5 Advances of the STAT3 signaling pathways involving breast cancer chemoresistance ENSG00000128342 ENSG00000168610 PMC7048131__F4 Advances of the STAT3 signaling pathways involving breast cancer metastasis ENSG00000087245 ENSG00000138639 ENSG00000099985 ENSG00000137193 ENSG00000112561 ENSG00000100985 ENSG00000168610 ENSG00000284984 PMC7048131__F1 Classical IL-6/STAT3 signaling pathway in cancer cells ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC5945810__F1 TLR2/1 signaling cascade and respective regulatory nodes ENSG00000125538 ENSG00000134070 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC9582503__F1 MicroRNA and Their Potential Role in Conjunctival Disorders ENSG00000128191 ENSG00000113360 ENSG00000132341 PMC3165102__F1 TGFB/SMAD/GLI2 signaling axis in cancer progression and metastasis ENSG00000128602 PMC2634812__F5 Schematic of counterbalancing and dose-dependent regulatory forces that act on T-cell precursors through the ETP and DN2 stages ENSG00000148400 ENSG00000107485 ENSG00000196092 ENSG00000269404 PMC2634812__F4 Myeloid diversion pathways for advanced pro-T cells by re-introduction of C/EBPA or PU.1 ENSG00000157557 ENSG00000148400 ENSG00000122877 ENSG00000107485 ENSG00000171791 ENSG00000005381 PMC8307416__F5 Identification and Roles of miR-29b-1-3p and miR29a-3p-Regulated and Non-Regulated lncRNAs in Endocrine-Sensitive and Resistant Breast Cancer Cells ENSG00000170365 ENSG00000123144 ENSG00000135903 ENSG00000168036 ENSG00000107485 ENSG00000151617 ENSG00000283060 ENSG00000140464 ENSG00000089225 PMC2634812__F3 Stepwise respecification of ETP and DN2 cells by GATA-3 overexpression ENSG00000107485 ENSG00000163751 ENSG00000179348 ENSG00000154096 PMC8584434__F4 Pathogenic Basis of Thromboinflammation and Endothelial Injury in COVID-19: Current Findings and Therapeutic Implications ENSG00000003436 ENSG00000130234 PMC5697340__F1 Stages of innate lymphoid cell (ILC) development ENSG00000134460 ENSG00000165030 ENSG00000109906 ENSG00000107485 ENSG00000198846 PMC11203986__F7 HIRA-associated pathway ENSG00000182481 ENSG00000100084 ENSG00000136997 PMC11203986__F6 CAF-1-associated pathway ENSG00000100084 ENSG00000111875 ENSG00000132646 PMC4058004__F1 Simplified biotransformation scheme of tamoxifen in man. Tamoxifen is mainly N-demethylated to NDM-TAM and subsequently 4-hydroxylated to endoxifen ENSG00000244474 PMC11203986__F8 NAP1L1-associated pathway ENSG00000135446 ENSG00000105810 PMC8817856__F8 ROS/GRK2/HIF-1A/NLRP3 Pathway Mediates Pyroptosis of Fibroblast-Like Synoviocytes and the Regulation of Monomer Derivatives of Paeoniflorin ENSG00000278718 PMC9274484__F4 Gut microbiome in gastrointestinal cancer: a friend or foe? ENSG00000181847 ENSG00000121058 ENSG00000168036 ENSG00000172936 ENSG00000136869 PMC6135677__F7 Sketch diagram illustrated the target genes by the selected miRNAs in ROS-AKT-cyclinsenescence pathway ENSG00000117020 ENSG00000135446 ENSG00000123374 ENSG00000118971 PMC9274484__F3 Gut microbiome in gastrointestinal cancer: a friend or foe? ENSG00000226275 ENSG00000161921 ENSG00000172936 ENSG00000136869 PMC2077853__F9 Role of Src family kinases and N-Myc in spermatogonial stem cell proliferation ENSG00000291971 PMC4153443__F1 The mammalian circadian clock ENSG00000005812 ENSG00000069667 PMC9274484__F2 Gut microbiome in gastrointestinal cancer: a friend or foe? ENSG00000012048 ENSG00000198793 ENSG00000168036 ENSG00000106100 ENSG00000168646 PMC9277653__F4 Comprehensive Review of Uterine Fibroids: Developmental Origin, Pathogenesis, and Treatment ENSG00000157554 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8955937__F11 WWOX/HIF1A Axis Downregulation Alters Glucose Metabolism and Predispose to Metabolic Disorders ENSG00000159399 PMC4499569__F2 Neuroprotective cross-talk involving the cytoprotective PI3K/AKT pathway ENSG00000169047 ENSG00000158828 PMC5840486__F1 Schematic illustration of the main hedgehog (Hh) pathway components ENSG00000106571 ENSG00000185669 ENSG00000164690 ENSG00000128602 PMC3312480__F1 Schematic view of potential targets and site of action of some biologics in IBD ENSG00000134982 PMC8168453__F2 Schematics of the TIM3/Gal9 signaling pathway in T cells ENSG00000291603 ENSG00000111537 ENSG00000213658 ENSG00000010810 PMC8168453__F4 Schematics of the TIM3/Gal9 pathway in innate immune cells ENSG00000111537 ENSG00000134982 ENSG00000136869 PMC9409562__F1 Type I interferons during host–fungus interactions: Is antifungal immunity going viral? ENSG00000135899 ENSG00000088888 ENSG00000105397 ENSG00000230034 ENSG00000164342 PMC8955937__F10 WWOX/HIF1A Axis Downregulation Alters Glucose Metabolism and Predispose to Metabolic Disorders ENSG00000159399 ENSG00000062485 PMC10180405__F3 BMP-2 and Wnt/Beta-catenin signaling pathways participate in the pharmacological activity of naringin in mediating osteogenic differentiation ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000168646 ENSG00000196628 PMC12123823__F1 Mechanisms underlying NET formation ENSG00000278718 ENSG00000135446 ENSG00000105810 ENSG00000168404 ENSG00000005381 ENSG00000285379 PMC7697962__F2 Top two networks constructed by ingenuity pathway analysis (IPA) showing interactions between the top 100 differentially expressed genes (DEGs) in the dendritic cells (DCs) from patients with allergies ENSG00000157554 ENSG00000167384 ENSG00000157227 ENSG00000115718 ENSG00000095794 PMC10525949__F6A Transcriptomics Reveal the Effects of Breeding Temperature on Growth and Metabolism in the Early Developmental Stage of Platax teira ENSG00000157184 ENSG00000169291 ENSG00000150991 ENSG00000100979 PMC8222468__F2 Extracellular vesicles in podocyte autophagy in kidney disease ENSG00000126775 ENSG00000198793 ENSG00000284161 ENSG00000167658 ENSG00000167965 ENSG00000140464 PMC3117856__F3 MAPK signaling pathway ENSG00000138798 ENSG00000130159 ENSG00000099942 ENSG00000026103 PMC2994991__F6 Reporter gene assay for HIF-1 activity PMC4946894__F1 Apoptosis pathways in various organisms ENSG00000157933 PMC8616058__F1 Exosomes in Ageing and Motor Neurone Disease: Biogenesis, Uptake Mechanisms, Modifications in Disease and Uses in the Development of Biomarkers and Therapeutics ENSG00000129219 ENSG00000111737 PMC6314011__F3 The interplay between intrinsic (i.e., circadian clock) and neurohumoral factors in circadian control of both metabolism and redox tone ENSG00000159399 ENSG00000062282 PMC2832945__F7 Proposed mechanism for B2M mAb inhibition of AR and cell proliferation, survival, and progression through a MAPK/SREBP-1 signaling pathway in prostate cancer cells ENSG00000273686 ENSG00000026103 PMC5088563__F1 Signaling cascades implicated in developmental cell death and tissue homeostasis ENSG00000137275 ENSG00000167468 ENSG00000136869 ENSG00000171791 ENSG00000168610 ENSG00000285379 ENSG00000164342 PMC6390240__F4 Modules of core PPI networks of baicalein against HCC ENSG00000012048 ENSG00000134308 ENSG00000111530 ENSG00000123374 ENSG00000146648 ENSG00000130726 PMC5168844__F1 Network structure for RAS signaling pathway in Head and Neck Squamous Cell Carcinoma (HNSC) ENSG00000157404 ENSG00000033327 ENSG00000002330 ENSG00000109320 ENSG00000050748 ENSG00000146648 PMC6964830__F8 Functional network of proteins in stage 3 breast cancer samples ENSG00000113645 ENSG00000114978 PMC8757397__F1 Pathophysiology of COVID-19-associated coagulopathy ENSG00000108691 ENSG00000003436 ENSG00000130234 ENSG00000125538 ENSG00000122194 ENSG00000132693 PMC2909654__F5 Examples of human disease phenotype correlations in the absence of metabolite sharing but detected by flux correlations ENSG00000066926 ENSG00000126088 ENSG00000188690 ENSG00000036473 PMC3820238__F1 Schematic overview of TGFB signaling ENSG00000137834 ENSG00000106683 ENSG00000163914 ENSG00000156574 PMC4836751__F5 Transcriptional Profiling of Ileocecal Valve of Holstein Dairy Cows Infected with Mycobacterium avium subsp. Paratuberculosis ENSG00000291603 ENSG00000213658 ENSG00000177606 ENSG00000104894 ENSG00000142273 PMC8362800__F2 SPOP and CUL3 Modulate the Sonic Hedgehog Signal Response Through Controlled Degradation of GLI Family Transcription Factors ENSG00000121067 ENSG00000164690 ENSG00000128602 PMC6557983__F1 Pathogenesis of hRSV and molecules with a biomarker potential induced in the airways during hRSV infection ENSG00000163464 ENSG00000137033 ENSG00000172936 ENSG00000145777 ENSG00000136869 ENSG00000164342 PMC2837270__F8 Seoul virus suppresses NFKB-mediated inflammatory responses of antigen presenting cells from Norway rats ENSG00000174125 ENSG00000108691 ENSG00000226275 ENSG00000077150 ENSG00000263528 ENSG00000108342 ENSG00000134070 ENSG00000172936 ENSG00000125347 ENSG00000064012 ENSG00000028137 PMC8395571__F7 Pathway-targets analysis ENSG00000134057 ENSG00000089685 ENSG00000128052 ENSG00000131747 ENSG00000145386 ENSG00000149554 PMC3370249__F7 Proposed FasL-Met signaling pathway ENSG00000168610 PMC7774657__F1 Aspirin’s role in colorectal cancer prevention Cyclooxygenase (COX) dependent pathway (Left panel): Inhibition of COX-1 in platelets and COX-2 in epithelial cells ENSG00000163739 ENSG00000168036 PMC6468861__F2 miRNA biogenesis pathway and various single nucleotide polymorphisms (SNPs) occurring at different steps of the pathway that play a pivotal role in prediction of breast cancer risk development ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC9288680__F10 Macrophage-derived apoptotic vesicles regulate fate commitment of mesenchymal stem cells via miR155 ENSG00000242252 PMC10757365__F3 Immune checkpoints in antitumor response: a potential antitumor immunotherapy ENSG00000115415 ENSG00000134982 ENSG00000125347 PMC10376142__F1 Cancer Drug Delivery Systems Using Bacterial Toxin Translocation Mechanisms ENSG00000140564 PMC3346695__F2 Cell signaling pathways involved in ischemic postconditioning ENSG00000002330 ENSG00000026103 PMC9029764__F2 Dangerous Liaisons in the Oxidative Stress Response to Leishmania Infection ENSG00000169245 ENSG00000164342 PMC6148086__F8 Schematic summary ENSG00000105329 ENSG00000198793 PMC6964830__F5 Functional network of proteins in stage 2 breast cancer samples, (confidence level = 0.150) ENSG00000114978 PMC4193347__F6 Germline PTEN Mutation Cowden Syndrome: An Under-Appreciated Form of Hereditary Kidney Cancer ENSG00000019991 ENSG00000143252 ENSG00000134086 ENSG00000117118 ENSG00000052795 ENSG00000112561 ENSG00000217128 PMC7464713__F7 Implemented model of the Wnt-independent Beta-catenin pathway ENSG00000164736 ENSG00000168036 ENSG00000196628 PMC8196972__F6 Impact of the rs1024611 Polymorphism of CCL2 on the Pathophysiology and Outcome of Primary Myelofibrosis ENSG00000108691 ENSG00000174059 ENSG00000121807 PMC3817731__F3 Activation of the EGFR pathway and the consequent engagement of the Ras/Raf/MAPK and PI3K/Akt pathways ENSG00000138798 ENSG00000146648 PMC2987484__F1 Pathway analysis on differentially expressed genes ENSG00000196754 ENSG00000145147 ENSG00000172009 ENSG00000184292 ENSG00000149295 ENSG00000106683 ENSG00000133019 ENSG00000110148 ENSG00000196549 ENSG00000162402 ENSG00000111837 ENSG00000170430 ENSG00000175426 ENSG00000169851 ENSG00000187678 ENSG00000142192 ENSG00000100285 ENSG00000165752 ENSG00000169242 ENSG00000157005 ENSG00000116157 ENSG00000102468 ENSG00000135698 ENSG00000184007 ENSG00000123360 ENSG00000118785 ENSG00000010810 ENSG00000182240 ENSG00000127616 PMC8517841__F6 Schlafen 11 expression in human acute leukemia cells with gain-of-function mutations in the interferon-JAK signaling pathway ENSG00000172716 ENSG00000105397 PMC2435243__F9 Several signaling pathways work together in the TGFB1-induced expression of CCN2/CTGF in primary human gingival fibroblasts ENSG00000070831 ENSG00000163914 ENSG00000198670 PMC3858190__F4 Pathways involved in sensing and responding to double-stranded RNA and other pathogen-associated molecular patterns were suppressed by SMD ENSG00000226275 ENSG00000088888 ENSG00000177606 ENSG00000113520 ENSG00000168040 PMC7563728__F1 Metabolic pathways and Snail target enzymes of catabolic metabolism ENSG00000180210 ENSG00000130957 ENSG00000078237 PMC3858190__F9 Ingenuity pathway analysis of differences between LPS and LPS + SMD (300mg/kg) with regard to reproductive hormones ENSG00000152661 ENSG00000276725 ENSG00000100410 ENSG00000162496 ENSG00000007237 ENSG00000198492 ENSG00000180964 ENSG00000197785 ENSG00000073849 ENSG00000109814 ENSG00000108179 ENSG00000162923 ENSG00000055163 ENSG00000197879 ENSG00000243927 ENSG00000105447 ENSG00000143179 ENSG00000288169 ENSG00000159399 ENSG00000164949 PMC10987845__F1 Glycan biosynthesis mutants were screened for immune stimulatory properties ENSG00000069482 PMC3169412__F1 Fatty-acid biosynthetic pathway for R ENSG00000182511 ENSG00000169710 ENSG00000280548 ENSG00000026103 PMC6771463__F6 Dual-Targeting AKT2 and ERK in cancer stem-like cells in neuroblastoma ENSG00000198793 PMC6119869__F3 The paradoxical HH pathway ENSG00000164690 PMC6119869__F2 The HH signalling pathway ENSG00000128602 PMC6982256__F5 2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents ENSG00000177169 PMC8275186__F1 Coordinated Cut and Bypass: Replication of Interstrand Crosslink-Containing DNA ENSG00000144554 ENSG00000132646 ENSG00000187790 ENSG00000070950 PMC3397315__F4 Summary of ion channel targets of the GSK-3 pathway PMC9048451__F2 Abnormal synaptic plasticity and impaired cognition in schizophrenia ENSG00000115419 PMC5999603__F8 The model of linc00462 regulation in PC ENSG00000099985 PMC8883537__F5 Deregulation of JAK2 signaling underlies primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma ENSG00000042832 ENSG00000081237 ENSG00000173757 ENSG00000121058 ENSG00000105639 ENSG00000168610 PMC6813250__F3 JA-mediated cold and freezing stress responses in plants ENSG00000164151 ENSG00000128915 PMC5666906__F6 The impact of EGFR-ERK pathway on the type I interferon response in human keratinocytes ENSG00000108691 ENSG00000115415 ENSG00000185745 ENSG00000147896 ENSG00000125347 ENSG00000146648 PMC8573303__F3 Effect of vitamin D, magnesium and zinc supplements on interferon signaling pathways and their relationship to control SARS-CoV-2 infection ENSG00000111012 ENSG00000102962 PMC5328970__F3 Sema3A signaling in bone remodeling ENSG00000006607 ENSG00000168036 ENSG00000197943 ENSG00000075213 PMC6119869__F4 Mechanisms of resistance to SMO inhibitors ENSG00000128602 PMC6385204__F7 Angiomotin-p130 inhibits Beta-catenin stability by competing with Axin for binding to tankyrase in breast cancer ENSG00000134982 ENSG00000168036 ENSG00000173273 PMC4538064__F3 Insights into the molecular mechanisms of methylmalonic acidemia using microarray technology ENSG00000149311 ENSG00000172680 ENSG00000170458 ENSG00000127191 ENSG00000164305 ENSG00000196712 ENSG00000026103 PMC3870411__F1 TNF Signals through TNFR1 and TNFR2 receptors (A) but abnormalities in this signaling pathway in autoimmunity (B) can favor a pathway of selective apoptosis due to a variety of protein signaling defects ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC3273665__F2 SREBPs in the innate immune response ENSG00000162711 ENSG00000239732 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000164342 ENSG00000142166 PMC9599708__F3 Copper-Dependent Kinases and Their Role in Cancer Inception, Progression and Metastasis ENSG00000177169 ENSG00000123395 ENSG00000002330 ENSG00000083290 PMC7053069__F7 Schematic of CPT’s anti-inflammatory mechanism in LPS-stimulated RAW264.7 cells ENSG00000172936 ENSG00000136869 ENSG00000079999 PMC5680590__F7 CAV1 orchestrates the TGFB response in HCC ENSG00000086991 ENSG00000146648 ENSG00000104081 PMC9162579__F4 Genome-Wide Mutant Screening in Yeast Reveals that the Cell Wall is a First Shield to Discriminate Light From Heavy Lanthanides ENSG00000088035 ENSG00000214160 PMC5875422__F8 Schematic shows the relationship between neuronal and oligodendrocyte metabolism ENSG00000185818 ENSG00000198964 ENSG00000205927 ENSG00000174607 PMC6103739__F7 Schematic diagrams of SOS1 activation ENSG00000159224 ENSG00000146648 PMC4344206__F1 Platelet signaling pathways ENSG00000167323 ENSG00000293604 ENSG00000145321 PMC9531149__F3 Role of extracellular granzyme B in wet age-related macular degeneration and fuchs endothelial corneal dystrophy ENSG00000197713 PMC9201572__F15 Shenkang Injection for Treating Renal Fibrosis-Metabonomics and Regulation of E3 Ubiquitin Ligase Smurfs on TGFB/Smads Signal Transduction ENSG00000157933 ENSG00000198742 PMC3666437__F5 Regulation of upregulated miRNAs on the downregulated mRNAs in antigen processing and presentation pathway and p53 signaling pathway ENSG00000175054 ENSG00000084093 ENSG00000111537 ENSG00000135446 ENSG00000186716 ENSG00000198793 ENSG00000136997 ENSG00000127022 ENSG00000112378 ENSG00000273686 ENSG00000105810 PMC10542959__F4 FOXM1 may be involved in diabetic nephropathy by regulating signaling pathways such as NFKB/NLRP3 and Wnt/Beta-catenin ENSG00000162711 ENSG00000168036 ENSG00000089163 PMC3717793__F1 Identification of acetylation-dependent regulatory mechanisms that govern the oncogenic functions of Skp2 ENSG00000145604 ENSG00000141232 ENSG00000100387 ENSG00000150907 ENSG00000113558 PMC10542959__F3 FOXM1 is involved in regulation of diabetes-related inflammatory responses ENSG00000111537 ENSG00000198793 PMC11927582__F3 Sufu plays an important regulatory role in Toll-like receptor (TLR)-mediated inflammatory responses ENSG00000162711 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC11927582__F2 LAT in the TCR pathway enhances signal transduction by sequestering inhibitory factors through a LLPS mechanism ENSG00000213658 PMC8350386__F1 MicroRNAs in Transforming Growth Factor-Beta Signaling Pathway Associated With Fibrosis Involving Different Systems of the Human Body ENSG00000137834 ENSG00000095739 ENSG00000175104 ENSG00000076604 PMC6766659__F6 Pathways that mediate the effects of NANOG on COL3 expression by senescent cells ENSG00000137834 ENSG00000291748 PMC9199556__F6 Central Neural Circuits Orchestrating Thermogenesis, Sleep-Wakefulness States and General Anesthesia States ENSG00000187688 ENSG00000005381 PMC8534183__F5 New Insights into the Pivotal Role of Iron/Heme Metabolism in TLR4/NFKB Signaling-Mediated Inflammatory Responses in Human Monocytes ENSG00000135776 ENSG00000066926 ENSG00000136869 ENSG00000115657 ENSG00000115107 PMC5868815__F4 In silico identification of microRNAs predicted to regulate N-myristoyltransferase and Methionine Aminopeptidase 2 functions in cancer and infectious diseases ENSG00000132906 ENSG00000104365 ENSG00000138795 ENSG00000002330 ENSG00000005339 ENSG00000157764 ENSG00000134982 ENSG00000109320 ENSG00000138798 ENSG00000198793 ENSG00000115904 ENSG00000168036 ENSG00000171791 ENSG00000169032 ENSG00000121879 ENSG00000164305 ENSG00000124762 ENSG00000117020 ENSG00000112242 ENSG00000277893 ENSG00000177606 ENSG00000123374 ENSG00000168646 ENSG00000139687 PMC5868815__F3 In silico identification of microRNAs predicted to regulate N-myristoyltransferase and Methionine Aminopeptidase 2 functions in cancer and infectious diseases ENSG00000124102 ENSG00000185634 ENSG00000002330 ENSG00000157764 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000158458 ENSG00000115904 ENSG00000065559 ENSG00000121879 ENSG00000124762 ENSG00000169752 ENSG00000110395 ENSG00000124882 ENSG00000177606 ENSG00000136997 ENSG00000166501 ENSG00000071051 ENSG00000143322 PMC9029562__F4 Neuromelanin in Parkinson’s Disease: Tyrosine Hydroxylase and Tyrosinase ENSG00000123454 ENSG00000107165 PMC3107200__F8 Chk2 and p53 Are Haploinsufficient with Dependent and Independent Functions to Eliminate Cells after Telomere Loss ENSG00000149311 ENSG00000175054 ENSG00000157933 PMC5383719__F3 Low-avidity signaling of B2-integrin regulates toll-like receptors (TLR) signaling in macrophages ENSG00000291971 ENSG00000198087 ENSG00000172936 ENSG00000136869 PMC2852602__F2 TLR/IL-1R signalling pathways ENSG00000239732 ENSG00000135218 ENSG00000187554 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC6274341__F1 Isoprenoid biosynthetic MVA pathway in the plant cell ENSG00000110921 ENSG00000197429 PMC9639265__F1 Endoplasmic reticulum stress targeted therapy for breast cancer ENSG00000128272 ENSG00000100219 PMC4209143__F2 Macroautophagy is regulated by several signalling pathways ENSG00000155792 ENSG00000110680 ENSG00000167965 ENSG00000084774 PMC9639265__F3 Endoplasmic reticulum stress targeted therapy for breast cancer ENSG00000128272 ENSG00000198793 ENSG00000100219 PMC9639265__F2 Endoplasmic reticulum stress targeted therapy for breast cancer ENSG00000128272 ENSG00000100219 ENSG00000168610 PMC9046545__F4 Signaling Pathway and Small-Molecule Drug Discovery of FGFR: A Comprehensive Review ENSG00000066468 ENSG00000160867 ENSG00000077782 PMC9046545__F3 Signaling Pathway and Small-Molecule Drug Discovery of FGFR: A Comprehensive Review ENSG00000110395 PMC9639265__F4 Endoplasmic reticulum stress targeted therapy for breast cancer ENSG00000128272 ENSG00000136997 ENSG00000100219 PMC9240045__F7 Schematic time-course changes in cellular processes in phosphorylase liver isoform knockdown (shPYGL) and control (shControl) U87MG glioblastoma (GBM) cells following high dose ionising radiation (IR) ENSG00000104812 ENSG00000291507 ENSG00000068976 ENSG00000100994 ENSG00000100504 PMC9537356__F5 On-Target Side Effects of Targeted Therapeutics of Cancer ENSG00000198793 PMC5746461__F5 Serotonin neuron development: shaping molecular and structural identities ENSG00000173404 ENSG00000170214 ENSG00000139287 ENSG00000163064 ENSG00000146477 ENSG00000107485 ENSG00000165646 ENSG00000179348 ENSG00000121764 ENSG00000179520 PMC4322535__F3 Signalling pathway of renal tumour-propagating cell membrane markers and “cancer stem cell” markers ENSG00000170365 ENSG00000026508 ENSG00000168036 ENSG00000121966 ENSG00000108840 PMC4209143__F3 Macroautophagy in the immune system ENSG00000239732 ENSG00000186716 PMC2672206__F7 Regulation of osteogenic differentiation of MC3T3-E1 cells by substrate rigidity PMC8651982__F5 T-Cell Factors as Transcriptional Inhibitors: Activities and Regulations in Vertebrate Head Development ENSG00000138795 ENSG00000104517 ENSG00000064393 ENSG00000146648 PMC9372833__F5 Occurrence of MYD88L265P and CD79B mutations in diffuse large b cell lymphoma with bone marrow infiltration: A case report ENSG00000105369 ENSG00000042832 ENSG00000007312 ENSG00000198793 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000010671 ENSG00000198286 PMC8836162__F4 EphrinB2–EphB4 Signaling in Neurooncological Disease ENSG00000128917 ENSG00000112715 ENSG00000146648 PMC8836162__F2 EphrinB2–EphB4 Signaling in Neurooncological Disease ENSG00000182968 ENSG00000126458 PMC8195694__F1 Interferon therapy in patients with SARS, MERS, and COVID-19: A systematic review and meta-analysis of clinical studies ENSG00000088888 ENSG00000130234 ENSG00000184012 ENSG00000164342 PMC11039848__F2 How traditional Chinese medicine can prevent recurrence of common bile duct stones after endoscopic retrograde cholangiopancreatography? ENSG00000276559 ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC4624093__F1 Biomarkers of Angiogenesis in Colorectal Cancer ENSG00000291971 ENSG00000112715 ENSG00000150630 PMC5705427__F3 Psoriasis: A mixed autoimmune and autoinflammatory disease ENSG00000141527 ENSG00000081041 ENSG00000163739 PMC4437805__F1 Wnt signaling pathways ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000185269 PMC9413544__F1 Neuroprotective Natural Products’ Regulatory Effects on Depression via Gut–Brain Axis Targeting Tryptophan ENSG00000102977 PMC10648403__F6 Expression profiles of genes involved in the phenylpropanoid biosynthesis pathway ENSG00000091704 ENSG00000163751 ENSG00000084774 PMC8910922__F1 Recent Advances in Understanding Nrf2 Agonism and Its Potential Clinical Application to Metabolic and Inflammatory Diseases ENSG00000042832 ENSG00000205795 ENSG00000079999 PMC3066660__F6 Significantly expressed genes in cytokine–cytokine receptor interaction pathway disturbed by SM at different time points ENSG00000108702 ENSG00000104899 ENSG00000019991 ENSG00000099985 ENSG00000111321 ENSG00000187266 ENSG00000157005 ENSG00000064300 ENSG00000122025 ENSG00000049130 ENSG00000135960 ENSG00000117400 ENSG00000102970 ENSG00000026103 ENSG00000291368 PMC5094708__F6 Mesenchymal Stem/Stromal Cells under Stress Increase Osteosarcoma Migration and Apoptosis Resistance via Extracellular Vesicle Mediated Communication ENSG00000169710 PMC5132145__F4 Phagocytosis of apoptotic corpses ENSG00000038382 ENSG00000063245 ENSG00000171100 ENSG00000070831 ENSG00000134982 ENSG00000073712 PMC5850397__F1 Mechanism of apoptosis induction by Vesicular stomatitis virus (VSV) in the infected cell ENSG00000101146 ENSG00000110713 PMC4703580__F1 Negative regulation of TLR signaling in myeloid cells—Implications for autoimmune diseases ENSG00000150907 ENSG00000172936 ENSG00000162772 ENSG00000150455 ENSG00000175104 PMC3888942__F6 Axon navigation pathway targeting by miRNAs that differentially associate with Ago2 in an activity-dependent manner ENSG00000145147 ENSG00000090776 ENSG00000288455 ENSG00000121966 ENSG00000133216 ENSG00000182541 ENSG00000196576 ENSG00000182511 ENSG00000172602 ENSG00000010810 ENSG00000163914 ENSG00000076356 ENSG00000154134 ENSG00000185008 ENSG00000154928 ENSG00000198910 PMC5951297__F4 Identified pathway between EGFR and JUN for Loi’s breast cancer dataset ENSG00000084676 ENSG00000177606 ENSG00000146648 PMC2645904__F3 Schematic representations of potential signaling pathways involved in serum-deprived retinal ganglion cell-5 cells ENSG00000109819 ENSG00000213918 ENSG00000117054 ENSG00000111537 ENSG00000138798 ENSG00000074219 ENSG00000163631 PMC3116645__F1 Mammalian target of rapamycin (mTOR) signaling pathway ENSG00000169047 ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC6349890__F7 Autophagy attenuates tubulointerstital fibrosis through regulating transforming growth factorB and NLRP3 inflammasome signaling pathway ENSG00000162711 ENSG00000135605 PMC6933909__F8 Schematic representation of the working model ENSG00000198793 ENSG00000129173 PMC2779188__F1 Genes involved in the vitamin D pathway ENSG00000115602 ENSG00000205221 ENSG00000019186 ENSG00000145321 ENSG00000186104 ENSG00000135929 PMC8895170__F3 Correlation between betatrophin/angiogenin-likeprotein3/lipoprotein lipase pathway and severity of coronary artery disease in Kazakh patients with coronary heart disease ENSG00000277494 ENSG00000042832 ENSG00000132855 PMC5168844__F2 Network structure for PI3K signaling pathway in Lung Adenocarcinoma (LUAD) ENSG00000132906 ENSG00000109320 ENSG00000153094 ENSG00000136997 ENSG00000175305 PMC5216781__F4 Overexpression of TELO2 decreases survival in human high-grade gliomas ENSG00000101407 ENSG00000149311 ENSG00000175054 ENSG00000198793 ENSG00000121879 ENSG00000146648 ENSG00000175792 PMC5241525__F1 Several signalling pathways can induce epithelial-mesenchymal transition in pancreatic cancer cells for example Notch, transforming growth factorB, Midkine, hypoxia-inducible factor-1A and tumor necrosis factorA ENSG00000105329 PMC3084000__F1 Glioma-Associated Oncogene Family Zinc Finger 1 Expression and Metastasis in Patients With Head and Neck Squamous Cell Carcinoma Treated With Radiation Therapy (RTOG 9003) ENSG00000140323 ENSG00000106571 ENSG00000117425 ENSG00000164161 ENSG00000154309 ENSG00000128602 ENSG00000118971 PMC5009320__F5 3′-hydroxy-3,4,5,4′-tetramethoxystilbene, the metabolite of resveratrol analogue DMU-212, inhibits ovarian cancer cell growth in vitro and in a mice xenograft model ENSG00000132906 ENSG00000198793 ENSG00000123374 ENSG00000112378 ENSG00000196470 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC3021097__F2 Functional significance of itpkc_3 on ITPKC mRNA and Ca2+/NFAT pathway ENSG00000134982 ENSG00000145321 ENSG00000086544 PMC4703580__F5 Negative regulation of TLR signaling in myeloid cells—Implications for autoimmune diseases ENSG00000172936 PMC3919687__F6 Kinetic changes in gene expression of selected components of Th2 responses ENSG00000102145 ENSG00000105397 ENSG00000178573 ENSG00000105639 ENSG00000168610 PMC3919687__F5 Kinetic changes in gene expression of selected components of the Wnt/Beta-catenin signaling pathway in aging CD8+ T cells ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000128602 PMC5417249__F1 Shared coregulator GRIP1 in the GR and type I IFN signaling networks ENSG00000213928 ENSG00000105397 ENSG00000172936 ENSG00000136869 ENSG00000155974 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC4136196__F5 Coinfection of Filifactor alocis with P ENSG00000166794 ENSG00000070756 ENSG00000165119 ENSG00000159335 PMC9501144__F5 Resveratrol and Some of Its Derivatives as Promising Prophylactic Treatments for Neonatal Hypoxia-Ischemia ENSG00000096717 ENSG00000106459 PMC8181394__F3 Cholesterol Metabolic Reprogramming in Cancer and Its Pharmacological Modulation as Therapeutic Strategy ENSG00000130164 ENSG00000113161 ENSG00000104549 ENSG00000130810 PMC8181394__F2 Cholesterol Metabolic Reprogramming in Cancer and Its Pharmacological Modulation as Therapeutic Strategy ENSG00000113161 ENSG00000104549 ENSG00000075239 PMC6598098__F6 Putative C4pathway in Alloteropsis semialata ENSG00000173599 ENSG00000172005 PMC4208677__F4 Ingenuity canonical pathway analysis ENSG00000081181 ENSG00000187741 ENSG00000112039 ENSG00000158169 ENSG00000166851 ENSG00000168610 ENSG00000139618 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000111537 ENSG00000105397 ENSG00000144554 ENSG00000115415 ENSG00000197299 ENSG00000051180 ENSG00000185591 ENSG00000175104 ENSG00000095002 ENSG00000123268 ENSG00000156273 PMC2678071__F1 Graphical representation of the gp130/JAK/STAT pathway ENSG00000099985 ENSG00000128342 PMC12144116__F0 GAS6/AXL signaling promotes M2 microglia efferocytosis to alleviate neuroinflammation in sepsis-associated encephalopathy ENSG00000167601 ENSG00000185591 ENSG00000168610 PMC8855423__F6 Lovastatin Inhibits RhoA to Suppress Canonical Wnt/Beta-Catenin Signaling and Alternative Wnt-YAP/TAZ Signaling in Colon Cancer ENSG00000168036 PMC3245506__F4 Network of differentially expressed genes in HMGA1 transgenics at 12 months (nonparametric approach) ENSG00000072571 ENSG00000147488 ENSG00000003436 ENSG00000102753 ENSG00000091972 ENSG00000110448 ENSG00000111728 ENSG00000114030 ENSG00000134308 ENSG00000160223 ENSG00000105246 ENSG00000198125 PMC10380785__F3 Lignin, the Lignification Process, and Advanced, Lignin-Based Materials ENSG00000084774 PMC3245506__F3 Network of differentially expressed genes in transgenics at 2 months (parametric and nonparametric approaches) ENSG00000027075 ENSG00000134460 ENSG00000142192 ENSG00000112964 ENSG00000162595 ENSG00000113161 ENSG00000189430 ENSG00000273686 ENSG00000132185 ENSG00000127191 ENSG00000125347 ENSG00000186810 ENSG00000226275 ENSG00000143801 ENSG00000197540 ENSG00000026508 PMC3245506__F2 Network of differentially expressed genes in HMGA1 transgenics at 2 months (parametric approach) ENSG00000027075 ENSG00000134460 ENSG00000142192 ENSG00000226275 ENSG00000186395 ENSG00000143801 ENSG00000186480 ENSG00000189430 ENSG00000132478 ENSG00000180644 ENSG00000283060 ENSG00000125347 PMC3245506__F1 Network of differentially expressed genes in HMGA1 transgenics at 2 months (nonparametric CAM approach) ENSG00000027075 ENSG00000100448 ENSG00000111728 ENSG00000077984 ENSG00000277804 ENSG00000189430 ENSG00000277571 ENSG00000134371 ENSG00000122223 ENSG00000145649 ENSG00000198125 ENSG00000005381 ENSG00000139687 PMC3245506__F6 Network of differentially expressed genes in transgenics at 12 months (parametric and nonparametric approaches) ENSG00000142192 ENSG00000102753 ENSG00000134982 ENSG00000134215 ENSG00000111728 ENSG00000072274 ENSG00000101057 ENSG00000145386 ENSG00000104921 ENSG00000117322 ENSG00000072571 ENSG00000113328 ENSG00000107263 ENSG00000171848 ENSG00000213694 ENSG00000198125 ENSG00000175305 PMC3245506__F5 Network of differentially expressed genes in HMGA1 transgenics at 12 months (parametric approach) ENSG00000124802 ENSG00000157106 ENSG00000182541 ENSG00000113328 ENSG00000138764 ENSG00000117650 ENSG00000112739 ENSG00000113318 ENSG00000149269 ENSG00000198125 ENSG00000135018 ENSG00000076382 ENSG00000184216 ENSG00000198625 PMC7842749__F8 Mutant Huntingtin Is Cleared from the Brain via Active Mechanisms in Huntington Disease ENSG00000197386 ENSG00000171885 PMC11561128__F8 GLS2-mediated glutaminolysis accelerated AS process by encouraging endothelial mitochondrial dysfunction and pyroptosis via SIRT3/FOXO3a axis ENSG00000278718 ENSG00000162711 ENSG00000135423 ENSG00000142082 PMC9553361__F2 Molecular Mechanisms of Defective Copper Metabolism in Diabetic Cardiomyopathy ENSG00000145321 PMC5356597__F3 GADD45B, an anti-tumor gene, inhibits avian leukosis virus subgroup J replication in chickens ENSG00000145604 ENSG00000118007 ENSG00000170458 ENSG00000132646 ENSG00000123374 ENSG00000164754 ENSG00000205250 ENSG00000277273 ENSG00000276876 ENSG00000093009 PMC2923430__F9 Immune Response ENSG00000039537 ENSG00000113600 ENSG00000291559 ENSG00000166278 PMC4758681__F6 The mechanism of Wnt-mediated suppression of osteoclast differentiation ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000131196 PMC7367812__F2 Contribution of monocytes and macrophages to the local tissue inflammation and cytokine storm in COVID-19: Lessons from SARS and MERS, and potential therapeutic interventions ENSG00000213928 ENSG00000187608 ENSG00000102871 ENSG00000130159 ENSG00000127191 ENSG00000164305 ENSG00000276561 ENSG00000172183 ENSG00000169245 ENSG00000183735 ENSG00000130234 ENSG00000185201 ENSG00000184012 ENSG00000147896 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000121060 ENSG00000164342 PMC3226315__F1 Recent focus in JMML has concentrated on using the information gained from knowledge of these molecular defects in order to design targeted drug therapy ENSG00000196712 PMC5727313__F1 The B‐catenin‐dependent Wnt signalling cascade in the ON‐state ENSG00000281324 ENSG00000162337 ENSG00000006712 ENSG00000134982 ENSG00000168036 ENSG00000124253 PMC7022273__F2 : Ca2+-calpain, cAMP- exchange protein directly activated by cAMP (Epac)- phosphoinositide-specific phospholipase CE (PLCE)-inositol phosphate 3 (IP3), and inositol signaling pathways of autophagy regulation ENSG00000126775 ENSG00000150907 ENSG00000177606 ENSG00000112561 ENSG00000189403 ENSG00000181467 ENSG00000145782 ENSG00000057663 PMC8551632__F5 Cyclin-Dependent Kinase 5 Regulatory Subunit Associated Protein 3: Potential Functions and Implications for Development and Disease ENSG00000173039 ENSG00000168036 ENSG00000112715 PMC7022273__F3 Binding of tumor necrosis factor A (TNFA) with TNF receptor activates the receptor, which recruits TNFR1-associated death domain protein (TRADD) ENSG00000137275 ENSG00000102871 ENSG00000144848 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC479700__F1 IFN-Gamma-inducible CIITA transcription from the type IV promoter is mediated by the Janus Kinase-1/Signal Transducers and Activators of Transcription-1 (JAK-1/STAT-1) signaling pathway ENSG00000115415 PMC7616045__F1 Serine synthesis pathway, folate cycle and methionine cycle ENSG00000228716 ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC7080263__F5 RNA-seq transcriptomic analysis reveals genes mediating salt tolerance through rapid triggering of ion transporters in a mutant barley ENSG00000105722 ENSG00000196511 ENSG00000100485 PMC8651982__F1 T-Cell Factors as Transcriptional Inhibitors: Activities and Regulations in Vertebrate Head Development ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000143032 PMC7864737__F4 Target genes in the mTOR signaling pathway ENSG00000198793 ENSG00000155792 PMC3654985__F4 Peritumoral (P) activated hepatic stellate cells (HSCs) and intratumoral myofibroblasts (T) ENSG00000157184 ENSG00000149311 ENSG00000150991 ENSG00000100979 ENSG00000112378 ENSG00000213523 PMC7998496__F1 Mode of curcumin actions as anti-cancer agent on the key molecular targets in GBM ENSG00000164690 ENSG00000128602 PMC1774677__F1 Diagrammatic indication of the cytokines, transcription factors, and signalling molecules which polarise virgin CD4 cells into T helper cell type I cells ENSG00000138378 ENSG00000115415 ENSG00000168610 PMC8745665__F2 Insulin-like Growth Factor Signalling Pathway in Cardiac Development and Regeneration ENSG00000003056 ENSG00000171105 ENSG00000002330 ENSG00000197081 ENSG00000150907 ENSG00000169047 ENSG00000168036 PMC4449428__F1 TGFB signaling in gliomagenesis and its targeting ENSG00000124766 ENSG00000163453 ENSG00000128342 ENSG00000083799 ENSG00000283060 ENSG00000125968 PMC5356913__F2 Soluble fibrinogen like protein 2 (sFGL2), the novel effector molecule for immunoregulation ENSG00000163914 ENSG00000010671 PMC2994209__F1 HER receptors and their ligands ENSG00000109321 ENSG00000163235 ENSG00000124882 ENSG00000113070 ENSG00000138798 ENSG00000158458 ENSG00000146648 ENSG00000169752 PMC2923187__F8 Hybrid Models Identified a 12-Gene Signature for Lung Cancer Prognosis and Chemoresponse Prediction ENSG00000140992 ENSG00000262785 ENSG00000142192 ENSG00000153201 ENSG00000136938 ENSG00000205250 ENSG00000111537 ENSG00000159720 ENSG00000066044 ENSG00000125538 ENSG00000133740 ENSG00000146648 ENSG00000122512 PMC5587989__F2 YAP is regulated by various factors during hepatocarcinogenesis in addition to the members of the Hippo signaling pathway ENSG00000071575 ENSG00000166167 ENSG00000076706 PMC5587989__F1 Hippo/YAP signaling pathway maintains the balance between cell proliferation and apoptosis ENSG00000150457 ENSG00000131023 PMC8844466__F6 In silico Analysis of SARS-CoV-2 ORF8-Binding Proteins Reveals the Involvement of ORF8 in Acquired-Immune and Innate-Immune Systems ENSG00000131323 ENSG00000164342 PMC8957335__F2 Research Progress of Bufalin in the Treatment of Hepatocellular Carcinoma ENSG00000106571 ENSG00000168036 ENSG00000128602 PMC5393956__F2 mTORC1 and mTORC2 in cancer and the tumor microenvironment PMC8699317__F5 CD44: A Multifunctional Mediator of Cancer Progression ENSG00000066468 ENSG00000170961 ENSG00000122691 ENSG00000026508 PMC3358519__F1 Schematic diagram of the cholinergic anti-inflammatory pathway (CAP) ENSG00000087085 ENSG00000168610 PMC3924851__F2 New Function of Type I IFN: Induction of Autophagy ENSG00000152348 ENSG00000213928 ENSG00000115415 ENSG00000169047 ENSG00000144848 ENSG00000147896 ENSG00000145782 ENSG00000142166 PMC6977532__F2 Sepsis on AHR and inflammatory factors ENSG00000291971 ENSG00000125538 ENSG00000136869 ENSG00000168610 ENSG00000106546 PMC3268941__F1 Canonical Wnt/Beta-catenin and non-canonical Wnt signaling pathways ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000168036 PMC5148031__F5 Developmental Stage, Muscle and Genetic Type Modify Muscle Transcriptome in Pigs: Effects on Gene Expression and Regulatory Factors Involved in Growth and Metabolism ENSG00000166819 ENSG00000178860 ENSG00000168000 ENSG00000122877 ENSG00000168036 ENSG00000265972 ENSG00000175029 ENSG00000109787 ENSG00000057663 ENSG00000176692 ENSG00000125398 ENSG00000143379 ENSG00000134324 ENSG00000100219 ENSG00000285485 ENSG00000114115 ENSG00000109670 PMC5464927__F4 Regulation of Beta-catenin activity and function in cancer: therapeutic opportunities ENSG00000283781 ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000168646 ENSG00000061938 PMC2831839__F9 A proposed mechanism of MNTX synergistic effects with temsirolimus on inhibition of VEGF-induced angiogenic events ENSG00000124102 ENSG00000291971 ENSG00000198793 ENSG00000164327 PMC8044931__F2 Molecular mechanisms by which estrogens mediate chemoresistance ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000171791 ENSG00000146648 ENSG00000138385 PMC5090056__F1 Models of Hippo pathway in fly and mammals ENSG00000126016 ENSG00000186575 ENSG00000130545 ENSG00000114978 ENSG00000150457 ENSG00000132849 ENSG00000131023 PMC8702415__F3 Bioactive glasses incorporating less-common ions to improve biological and physical properties ENSG00000168036 PMC9094703__F1 Ventral Tegmental Area and Nucleus Accumbens as Circadian Oscillators: Implications for Drug Abuse and Substance Use Disorders ENSG00000069667 PMC8234974__F3 Engineered EV-Mimetic Nanoparticles as Therapeutic Delivery Vehicles for High-Grade Serous Ovarian Cancer ENSG00000198053 ENSG00000138798 PMC7842075__F7 Inhibition of mitochondrial carrier homolog 2 (MTCH2) suppresses tumor invasion and enhances sensitivity to temozolomide in malignant glioma ENSG00000285121 ENSG00000141086 ENSG00000100985 PMC9120866__F5 Dual-Role Ubiquitination Regulation Shuttling the Entire Life Cycle of the Flaviviridae ENSG00000106785 ENSG00000187608 ENSG00000111671 ENSG00000278211 ENSG00000108106 PMC4160261__F1 Single-Walled Carbon Nanotubes Alleviate Autophagic/Lysosomal Defects in Primary Glia from a Mouse Model of Alzheimer’s Disease ENSG00000177169 ENSG00000198793 ENSG00000005893 PMC7232714__F8 DIFFERENTIAL ROLES AND ACTIVATION OF MAMMALIAN TARGET OF RAPAMYCIN COMPLEXES 1 AND 2 DURING CELL MIGRATION IN PROSTATE CANCER CELLS ENSG00000138798 ENSG00000171759 ENSG00000164327 PMC8788756__F3 Physiology of Astroglial Excitability ENSG00000171105 ENSG00000104321 ENSG00000144935 PMC7911475__F2 Mechanism through which flavonoids induce cancer cell autophagy ENSG00000145321 ENSG00000168610 PMC9303584__F2 Skin cancer, including related pathways and therapy and the role of luteolin derivatives as potential therapeutics ENSG00000002330 ENSG00000157764 ENSG00000115415 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000168610 ENSG00000146648 ENSG00000196712 PMC7158350__F9 Roles of DEAD/DEAH box helicases in innate immune signaling pathways ENSG00000132109 ENSG00000239732 ENSG00000088888 ENSG00000109606 ENSG00000145833 ENSG00000174953 ENSG00000172936 ENSG00000168040 ENSG00000089737 ENSG00000276561 ENSG00000010671 ENSG00000164342 PMC7042114__F1 BNP plays critical roles in itch transmission ENSG00000169245 ENSG00000078747 ENSG00000179097 ENSG00000196639 ENSG00000170989 ENSG00000100985 ENSG00000157005 ENSG00000196689 ENSG00000115009 ENSG00000120937 ENSG00000119121 PMC9154101__F7 HbF induction by SAL ENSG00000128272 ENSG00000144895 PMC5978700__F2 Role of RAS enzymes in the EGFR signaling pathway ENSG00000163235 ENSG00000138798 ENSG00000146648 PMC9415417__F2 Calcimimetics in Treating Bone and Mineral Disorders Related to Chronic Kidney Disease ENSG00000198793 ENSG00000169884 ENSG00000036828 ENSG00000131196 PMC6162436__F1 Hippo pathway upstream modulation ENSG00000129474 ENSG00000101265 ENSG00000197905 ENSG00000139926 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000151718 ENSG00000074219 ENSG00000068028 ENSG00000186575 ENSG00000107551 ENSG00000169435 PMC6162436__F3 Repurposing of drugs on YAP (Yes-1 associated protein)-TEAD (transcriptional enhanced associate domain) system through cross-talking pathways ENSG00000129474 ENSG00000167601 ENSG00000169047 ENSG00000163914 ENSG00000166025 ENSG00000168036 ENSG00000150457 ENSG00000114019 ENSG00000131023 PMC3496019__F1 Cancer Stem Cells ENSG00000106571 ENSG00000144857 ENSG00000136997 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC6981417__F7 Differential ganglioside metabolism pathways between MDA-MB-231 GD3S+ clone #4 and MDA-MB-231 breast cancer cells ENSG00000135454 ENSG00000111728 ENSG00000169359 PMC6981417__F6 Differential ganglioside metabolism pathways between Hs 578T and MDA-MB-231 breast cancer cells ENSG00000135454 ENSG00000111728 ENSG00000169359 PMC8304479__F6 Polyphenol-Enriched Blueberry Preparation Controls Breast Cancer Stem Cells by Targeting FOXO1 and miR-145 ENSG00000198793 ENSG00000168610 PMC8469825__F1 Autophagy Dysregulation in Diabetic Kidney Disease: From Pathophysiology to Pharmacological Interventions ENSG00000177169 ENSG00000198793 ENSG00000145782 ENSG00000057663 ENSG00000136874 ENSG00000062716 PMC3496019__F2 Regulation of CSCs by inflammatory cytokine networks ENSG00000163464 ENSG00000168283 ENSG00000173039 ENSG00000168610 PMC8764452__F2 Emerging Role of Cancer-Associated Fibroblasts-Derived Exosomes in Tumorigenesis ENSG00000087245 ENSG00000110651 ENSG00000010278 ENSG00000164690 PMC6626338__F7 LUCAT1 and Wnt/beta-catenin signaling in breast cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8750814__F2 Elucidating T Cell and B Cell Responses to SARS-CoV-2 in Humans: Gaining Insights into Protective Immunity and Immunopathology ENSG00000139193 ENSG00000111537 ENSG00000145321 PMC2637783__F1 Toll-like receptor (TLR) signaling ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000184216 ENSG00000164342 PMC8082422__F2 Advances of Fibroblast Growth Factor/Receptor Signaling Pathway in Hepatocellular Carcinoma and its Pharmacotherapeutic Targets ENSG00000160867 ENSG00000168036 PMC4987369__F1 Schematic representation of a mechanism of action for cannabinoid based multi-target drugs ENSG00000117480 ENSG00000196689 PMC11726942__S1 Amantadine and its therapeutic role in spinal cord injury ENSG00000112799 ENSG00000182578 ENSG00000168329 ENSG00000118785 ENSG00000125538 ENSG00000110651 ENSG00000000971 ENSG00000049860 PMC3149084__F2 Single-run analysis of the yeast proteome by LC MS/MS ENSG00000213658 ENSG00000122966 ENSG00000100412 ENSG00000169299 ENSG00000013375 PMC3527239__F2 Metabolic pathways of TAG synthesis and degradation and their subcellular localization (adapted from and ) ENSG00000083857 ENSG00000163624 ENSG00000166123 ENSG00000128513 PMC10519146__F10 Intracellular innate immune response to avian influenza ENSG00000183735 ENSG00000152778 ENSG00000088888 ENSG00000111537 ENSG00000134321 ENSG00000185201 ENSG00000135114 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC3527239__F5 Compartmentalization of the Beta-oxidation pathway and the glyoxylate cycle ENSG00000146701 ENSG00000128513 PMC9020428__F2 Delivery of triptolide: a combination of traditional Chinese medicine and nanomedicine ENSG00000002330 ENSG00000144895 PMC3245119__F2 Non-canonical Wnt-signaling pathway ENSG00000110917 ENSG00000198626 ENSG00000087460 ENSG00000186469 PMC1431720__F7 Cytokine release in RAW 264.7 macrophages ENSG00000174125 ENSG00000111537 ENSG00000115415 ENSG00000136869 PMC4914160__F10 Model depicting autophagy receptor recruitment to depolarized mitochondria over time ENSG00000183735 ENSG00000123240 ENSG00000158828 PMC8258107__F1 Sweet Taste Is Complex: Signaling Cascades and Circuits Involved in Sweet Sensation ENSG00000185933 ENSG00000197635 ENSG00000183128 ENSG00000070985 ENSG00000196689 ENSG00000137841 PMC7483885__F2 Pathway map for the production of terpenoid compounds ENSG00000122966 ENSG00000172005 ENSG00000197429 PMC4994463__F4 “Inhibition of MMPs” signaling pathway at 1, 4, 7, and 14 days after nerve crush injury.Differentially expressed genes are shown in red (up-regulated) and green (downregulated) ENSG00000100234 ENSG00000087245 ENSG00000157150 ENSG00000175899 ENSG00000106305 ENSG00000105825 PMC3398465__F4 Systems analysis of salivary gland development and disease ENSG00000114554 ENSG00000075223 ENSG00000106571 ENSG00000164056 ENSG00000135960 ENSG00000044115 ENSG00000113070 ENSG00000138798 ENSG00000164690 ENSG00000128602 ENSG00000075213 ENSG00000062485 PMC6364034__F9 Working model illustrating that KSHV hijacks the citrulline-NO cycle to promote KSHV-induced cell proliferation and cellular transformation PMC7905684__F1 Novel targeted therapies for Parkinson’s disease ENSG00000090402 PMC3929010__F12 Reactive Oxygen Species in Inflammation and Tissue Injury ENSG00000132906 ENSG00000102871 ENSG00000130522 ENSG00000177606 ENSG00000168040 ENSG00000127191 ENSG00000164305 ENSG00000026103 PMC2970638__F8 Up-regulation of Paxillin and Focal Adhesion Signaling follows Dystroglycan Complex deletions and promotes a Hypertensive State of Differentiation ENSG00000162889 ENSG00000062485 ENSG00000026103 PMC5037279__F6 Proposed model for how mTORC1 activity controls pro-IL-1B expression ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC3929010__F10 Reactive Oxygen Species in Inflammation and Tissue Injury ENSG00000169429 ENSG00000162692 PMC8332866__F9 Epimedokoreanin C, a prenylated flavonoid isolated from Epimedium koreanum, induces non-apoptotic cell death with the characteristics of methuosis in lung cancer cells ENSG00000102189 ENSG00000115020 ENSG00000165527 PMC85825__F9 Model illustrating the relative positioning of aPKC within the NGF signaling cascades for survival and differentiation ENSG00000291971 ENSG00000064300 PMC10705325__F13 Study on the Effect of Oleic Acid-Induced Lipogenic Differentiation of Skeletal Muscle Satellite Cells in Yanbian Cattle and Related Mechanisms ENSG00000150991 ENSG00000100979 ENSG00000165269 PMC7976587__F3 Possible feedback loop between PTX3 and TNFA via NFKB signaling pathway in inflammation ENSG00000163739 ENSG00000125538 ENSG00000163661 PMC8513144__F1 Brain as an insulin-sensitive metabolic organ ENSG00000169047 ENSG00000198793 ENSG00000164327 ENSG00000106459 PMC11576080__F2 Therapeutic interventions that specifically target signaling pathways in B-cell lymphoma ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000010671 PMC6518034__F2 Schematic drawing of the details of the signaling pathways of five major cardiomyopathies ENSG00000002330 ENSG00000134982 ENSG00000026103 PMC11576080__F1 Major B-cell signaling pathways and their crosstalk ENSG00000104856 ENSG00000132906 ENSG00000105369 ENSG00000159224 ENSG00000002330 ENSG00000005882 ENSG00000007312 ENSG00000173039 ENSG00000010671 ENSG00000186716 ENSG00000172936 ENSG00000131323 ENSG00000198286 PMC8412938__F10 Summary model ENSG00000274619 ENSG00000107562 ENSG00000104918 ENSG00000197223 PMC6438043__F5 Pathway representing T cell signaling ENSG00000095585 ENSG00000100385 ENSG00000152495 ENSG00000081237 ENSG00000186716 ENSG00000177606 ENSG00000043462 ENSG00000124181 ENSG00000010671 ENSG00000141968 PMC3746496__F2 PKM2 activity is controlled by a tight regulatory network at the transcriptional, proteomic and metabolic level ENSG00000168036 ENSG00000168610 ENSG00000146648 ENSG00000115419 PMC8841346__F1 Beginner’s Guide to O-GlcNAc: From Nutrient Sensitive Pathway Regulation to Its Impact on the Immune System ENSG00000147162 ENSG00000198408 PMC5467995__F1 Major intracellular pathways leading to Type-I-IFN production ENSG00000164430 ENSG00000088888 ENSG00000167207 ENSG00000115415 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC8841346__F2 Beginner’s Guide to O-GlcNAc: From Nutrient Sensitive Pathway Regulation to Its Impact on the Immune System ENSG00000147162 ENSG00000198408 ENSG00000169047 PMC3634825__F2 Transcriptome Analysis of Skin Photoaging in Chinese Females Reveals the Involvement of Skin Homeostasis and Metabolic Changes ENSG00000104899 ENSG00000105329 ENSG00000139269 ENSG00000183691 ENSG00000156574 ENSG00000134363 ENSG00000067900 ENSG00000205250 ENSG00000169231 ENSG00000137801 ENSG00000143768 ENSG00000100387 ENSG00000243709 ENSG00000175189 ENSG00000135409 ENSG00000198742 ENSG00000113558 ENSG00000136997 ENSG00000080839 ENSG00000204217 ENSG00000114739 ENSG00000172201 PMC2686679__F12 Signaling pathway leading to Egr-1 biosynthesis in thrombin or carbachol-stimulated 39M1-81 cells ENSG00000084093 ENSG00000138798 PMC3634825__F3 Transcriptome Analysis of Skin Photoaging in Chinese Females Reveals the Involvement of Skin Homeostasis and Metabolic Changes ENSG00000112972 ENSG00000060982 ENSG00000078070 ENSG00000120437 ENSG00000138356 ENSG00000127884 ENSG00000117054 ENSG00000072210 ENSG00000143149 ENSG00000198754 ENSG00000083720 ENSG00000075239 ENSG00000113790 ENSG00000105552 ENSG00000128928 ENSG00000091140 ENSG00000117305 ENSG00000164904 ENSG00000138029 ENSG00000124370 ENSG00000131844 ENSG00000175198 ENSG00000137992 ENSG00000114054 ENSG00000151498 ENSG00000122971 PMC10865100__F1 Classical model of G1–S transition regulated by cyclins and cyclin-dependent kinases (CDK) ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 ENSG00000168610 PMC3025359__F1 Mincle- and Dectin-1-mediated signalling in response to mycobacteria ENSG00000187796 ENSG00000291971 ENSG00000134982 ENSG00000172936 ENSG00000175104 PMC11761900__F1 JAK/STAT signaling pathway and the selective inhibition of JAK1 by upadacitinib in inflammatory bowel disease ENSG00000105397 ENSG00000105639 PMC3719407__F4 Functional link between the BMP system and GnRH-induced FSH transcription ENSG00000170365 ENSG00000137834 PMC5442177__F2 Transcriptional regulation of hepatic mIndy mRNA levels in model organisms and humans ENSG00000168610 ENSG00000106546 PMC3679268__F7 GSK-3A Promotes Oncogenic KRAS Function in Pancreatic Cancer via TAK1-TAB Stabilization and Regulation of Non-Canonical NFKB ENSG00000104856 ENSG00000105723 PMC7385848__F1 Bile acid metabolism pathway.Two major pathways are involved in bile acid synthesis ENSG00000198610 ENSG00000167910 ENSG00000180432 ENSG00000099377 ENSG00000122787 ENSG00000135929 PMC3499662__F1 Cell-signaling pathways from the UPR to autophagy and ER stress-induced apoptosis ENSG00000100219 ENSG00000038002 ENSG00000127191 PMC6404485__F9 Neuroprotection mediated by the Wnt/Frizzled signaling pathway in early brain injury induced by subarachnoid hemorrhage ENSG00000135218 ENSG00000134982 ENSG00000168036 PMC2815088__F5 Hexosamine Signaling Pathway: O-GlcNAc cycling in feast or famine ENSG00000147162 ENSG00000198408 ENSG00000169047 ENSG00000198793 ENSG00000284161 ENSG00000167658 ENSG00000096717 PMC2815088__F4 The Hexosamine Signaling Pathway ENSG00000005882 ENSG00000169047 PMC6258484__F5 Pathway network and MAPK signaling ENSG00000087095 ENSG00000170458 ENSG00000155926 ENSG00000130159 ENSG00000081189 ENSG00000026103 PMC2719943__F1 Reduced levels of neurotransmitter-degrading enzyme PRCP promote obesity ENSG00000115138 ENSG00000166603 ENSG00000137509 PMC6952937__F1 Two different NFKB signaling pathways ENSG00000104856 ENSG00000125538 PMC3075579__F4 The PI3K pathway in TLR-signaling ENSG00000125538 ENSG00000172005 ENSG00000172936 ENSG00000175104 PMC2815088__F6 Hexosamine Signaling Pathway: O-GlcNAc cycling in feast or famine ENSG00000101751 ENSG00000147162 ENSG00000198408 ENSG00000198793 PMC6337659__F2 Proposed mechanisms of polycystins implication in CRC ENSG00000291971 ENSG00000198793 ENSG00000168036 PMC5514100__F15 HOXA11-AS co-expressed genes were significantly overrepresented in the non-small cell lung cancer pathway, revealed by KEGG pathway analysis– (http://www.kegg.jp/kegg/kegg1.html) ENSG00000132906 ENSG00000189283 ENSG00000146648 PMC4512023__F4 PTGS pathway deregulation during colorectal tumorigenesis PMC9301135__F1 Longevity-Promoting Pathways and Transcription Factors Respond to and Control Extracellular Matrix Dynamics During Aging and Disease ENSG00000155792 ENSG00000157625 ENSG00000096717 ENSG00000175104 ENSG00000184216 ENSG00000079999 PMC8388841__F1 Opposite Roles for ZEB1 and TMEJ in the Regulation of Breast Cancer Genome Stability ENSG00000149311 ENSG00000051180 PMC6565612__F1 The roles of the cAMP-PKA and cGMP-PKG pathway in DRG neuron hyperexcitability after peripheral injury or injury- related stress including chronic compression of DRG (CCD) and acute dissociation of DRG (ADD) ENSG00000154864 ENSG00000104321 ENSG00000145321 ENSG00000196689 PMC9376094__F9 TDP-43 suppressing apoptosis by modulating ABHD2 in HCC ENSG00000042832 PMC6136178__F8 DACT2 and the Beta-catenin/Cdc25c pathway ENSG00000138795 ENSG00000134057 ENSG00000168036 ENSG00000164488 PMC5509646__F6 The regulatory network of lipid accumulation with significant characteristics ENSG00000135218 ENSG00000133818 PMC5167032__F2 Dysregulated Toll‐like receptor signalling associated with advanced age ENSG00000174125 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC9218868__F2 Multifunctional Roles of MicroRNAs in Schistosomiasis ENSG00000187764 PMC8952333__F6 Advances in HIV-1 Assembly ENSG00000154451 ENSG00000140564 ENSG00000140575 PMC2806029__F2 Ammonia detoxification pathway and mitochondrial sirtuins ENSG00000118520 ENSG00000036473 ENSG00000089163 PMC8534485__F1 Porphyrias in the Age of Targeted Therapies ENSG00000110711 ENSG00000080819 ENSG00000126088 ENSG00000158578 ENSG00000256269 ENSG00000188690 PMC4479729__F1 The synthesis of glycoconjugates from glucose through the hexosamine biosynthetic pathway (HBP) ENSG00000147162 ENSG00000069482 ENSG00000198408 PMC10278599__F2 CAR T cell cytolytic mechanisms and paracrine effects ENSG00000111537 ENSG00000026103 PMC7697636__F1 Classical degradative autophagy (macroautophagy) ENSG00000152348 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC10308135__F4 Mechanistic insight into lysyl oxidase in vascular remodeling and angiogenesis ENSG00000118785 PMC11889768__F11 Potential pathways by which abscisic acid (ABA) influences 2-acetyl-1-pyrroline (2-AP) biosynthesis in aromatic rice ENSG00000100033 PMC7286881__F4 Exploring the mechanism of Shengmai Yin for coronary heart disease based on systematic pharmacology and chemoinformatics ENSG00000175206 ENSG00000105550 ENSG00000110799 ENSG00000180772 ENSG00000113161 ENSG00000112715 ENSG00000104368 ENSG00000137801 ENSG00000180210 ENSG00000150782 ENSG00000149968 ENSG00000130234 ENSG00000128052 ENSG00000100979 ENSG00000102104 ENSG00000171560 ENSG00000113889 ENSG00000145384 ENSG00000073756 ENSG00000132170 ENSG00000226275 ENSG00000108691 ENSG00000111537 ENSG00000117601 ENSG00000057593 ENSG00000100985 ENSG00000079435 PMC5758508__F8 Rationale for the problematic role of B2 adrenergic agonists in clinical trials ENSG00000173599 ENSG00000168036 ENSG00000001626 PMC7991574__F6 The used inhibitors and the signal transduction pathways involved in BDNF and C3 effects on SGN PMC8657675__F4 Intermittent Hypoxia on Cytokine Expression Involved in Insulin Resistance ENSG00000108691 ENSG00000104918 PMC5083752__F3 Hedgehog signaling activation in TNBC: interplay of ligand‐dependent and ligand‐independent mechanisms ENSG00000168283 ENSG00000164690 ENSG00000128602 ENSG00000163501 ENSG00000118257 PMC10528641__F2 Regulatory Mechanisms That Guide the Fetal to Postnatal Transition of Cardiomyocytes ENSG00000198793 ENSG00000150457 ENSG00000131023 PMC4472151__F5 Lineage specific differentiation for MSCs in an exquisitely coordinated process with critical regulators and indicators are shown ENSG00000152266 ENSG00000037965 ENSG00000157933 ENSG00000134982 ENSG00000120149 ENSG00000167941 ENSG00000138798 ENSG00000168036 ENSG00000164690 ENSG00000175104 ENSG00000128602 ENSG00000131196 PMC5083752__F1 Hedgehog signaling cascade ENSG00000164161 ENSG00000144857 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC4472151__F4 BMP signaling and its regulation ENSG00000157933 ENSG00000134982 ENSG00000120149 ENSG00000137203 ENSG00000175104 ENSG00000125968 PMC2989879__F3 The RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system ENSG00000106459 PMC2989879__F2 The RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system ENSG00000149311 ENSG00000168036 PMC6368966__F1 Proposed divergent role of Notch signaling in endothelial and smooth muscle cells ENSG00000148400 ENSG00000074181 ENSG00000204217 PMC6170333__F1 The synthetic pathway for development of the hyperbranched polymer based theranostic nanomedicine incorporating either A8 (HBP/A8/DOX) or A13 (HBP/A13/DOX) ENSG00000144857 PMC4885935__F1 Roles of sclerostin, Lrp4 and Wls in Wnt/Beta-catenin signals in osteoblasts ENSG00000281324 ENSG00000162337 ENSG00000134569 ENSG00000134982 ENSG00000168036 PMC7558374__F3 Known functions of FMDV non-structural proteins on immune escape ENSG00000163435 ENSG00000183735 ENSG00000213928 ENSG00000167207 ENSG00000115415 ENSG00000137100 ENSG00000131323 ENSG00000175104 ENSG00000145782 ENSG00000127191 ENSG00000276561 PMC7558374__F2 Known functions of FMDV structural proteins on immune escape ENSG00000168028 ENSG00000183735 ENSG00000213928 ENSG00000111537 ENSG00000115415 ENSG00000131323 ENSG00000127191 PMC11033278__F8 PPI interaction network ENSG00000179588 ENSG00000284468 ENSG00000151702 ENSG00000112304 ENSG00000164405 ENSG00000104783 ENSG00000184752 ENSG00000136371 ENSG00000173599 ENSG00000182220 ENSG00000133028 ENSG00000284194 ENSG00000179348 ENSG00000118596 ENSG00000160194 ENSG00000103202 ENSG00000145337 ENSG00000125741 ENSG00000166920 ENSG00000110719 ENSG00000213619 ENSG00000065518 ENSG00000189043 ENSG00000184076 ENSG00000119013 PMC5824531__F1 Signaling pathways linked to Insulin/IGF signaling in PDAC ENSG00000002330 ENSG00000150907 ENSG00000136111 ENSG00000171791 ENSG00000140443 PMC10889522__F6 Schematic illustration of YTHDF2 mediating the action of BDNF stimulating the proliferation of porcine follicle granulosa cells ENSG00000135446 ENSG00000198492 ENSG00000132646 PMC4411413__F2 Differential expression of genes involved in MAPK signaling pathway in mouse ovaries ENSG00000027075 ENSG00000157764 ENSG00000089472 ENSG00000138798 ENSG00000116717 ENSG00000130159 ENSG00000139625 ENSG00000120910 ENSG00000004455 ENSG00000143507 ENSG00000149269 ENSG00000177606 ENSG00000026103 PMC8748746__F2 DFT calculation of biosynthetic pathway of vaticahainol A and B ENSG00000108582 PMC5640934__F1 TGFB superfamily signaling and its involvement in decidualization ENSG00000107779 ENSG00000170365 ENSG00000123612 ENSG00000139567 ENSG00000135409 ENSG00000120693 ENSG00000134363 ENSG00000135503 ENSG00000204217 ENSG00000114739 PMC1482580__F4 EDA signaling in hair follicle development ENSG00000104856 ENSG00000186197 ENSG00000135960 ENSG00000104371 ENSG00000164690 PMC8786487__F3 Pharmacological Effects and Underlying Mechanisms of Licorice-Derived Flavonoids ENSG00000125538 ENSG00000177606 ENSG00000172936 ENSG00000136869 ENSG00000079999 PMC11395144__F3 Application of nanotechnology in MS and KOA treatment targeting TRPA1 inhibition ENSG00000104321 ENSG00000110931 ENSG00000131095 ENSG00000096717 PMC11395144__F2 Application of nanotechnology in breast cancer and PMA treatment targeting TRPA1 inhibition ENSG00000132329 ENSG00000104321 ENSG00000198793 PMC9630654__F1 Meta-analysis indicates that the regulation of cell motility is a non-intrinsic function of chemoattractant receptors that is governed independently of directional sensing ENSG00000070831 ENSG00000163914 ENSG00000084112 PMC7654410__F1 Neddylation inactivation by MLN4924 treatment or genetic deletion is involved in multiple regulatory responses within immune cells ENSG00000121807 PMC7504917__F2 Endogenous production of H2S and cross-talk between H2S/RSS and ROS/RNS in bacteria ENSG00000188158 PMC5819906__F7 miRNA-gene network contains six miRNAs and their target genes, which are involved in the insulin signaling pathway ENSG00000109819 ENSG00000140992 ENSG00000117020 ENSG00000281614 ENSG00000157764 ENSG00000288174 ENSG00000121879 ENSG00000159399 ENSG00000067177 PMC5819906__F6 Differentially expressed miRNA gene targets in the insulin signaling pathway ENSG00000171105 ENSG00000002330 ENSG00000150907 ENSG00000198793 ENSG00000026103 PMC6954688__F8 Activation of the NMRK2 path to NAD+ synthesis as an adaptive energy sparing mechanism in the failing heart ENSG00000077009 ENSG00000105835 PMC9323376__F8 Unkeito Suppresses RANKL-Mediated Osteoclastogenesis via the Blimp1–Bcl6 and NFKB Signaling Pathways and Enhancing Osteoclast Apoptosis ENSG00000164935 ENSG00000100985 ENSG00000164305 ENSG00000131196 PMC5349656__F1 Hh signaling pathway and RUSKI Hhat inhibitors ENSG00000128602 PMC5682227__F2 PID gene defects in the IFNG pathway ENSG00000096996 ENSG00000104365 ENSG00000159128 ENSG00000138378 ENSG00000187608 ENSG00000105397 ENSG00000100906 ENSG00000115415 ENSG00000140968 ENSG00000027697 ENSG00000179348 PMC4322943__F1 Phosphortlated Smad3 is stabilized by ERG in ERG-positive prostate cancer cells ENSG00000157554 PMC5975185__F1 Cocaine evokes a profile of oxidative stress and impacts innate antiviral response pathways in astrocytes ENSG00000112367 ENSG00000183735 PMC4180639__F7 Putative model of Ahnak-dependent activation of TGFB signaling PMC7898466__F7 TLS pathways for replication through Tg and EdA lesions ENSG00000042832 ENSG00000177084 ENSG00000122008 PMC8146344__F1 Substrate Stiffness and Stretch Regulate Profibrotic Mechanosignaling in Pulmonary Arterial Adventitial Fibroblasts ENSG00000087245 ENSG00000157193 ENSG00000291748 ENSG00000100985 ENSG00000150457 ENSG00000108821 ENSG00000131023 PMC7898466__F1 TLS pathways for replication through UV lesions ENSG00000101751 ENSG00000130997 ENSG00000177084 ENSG00000122008 PMC11786765__F7 MRNA expression of different signaling pathway genes ENSG00000162552 ENSG00000138795 PMC3820435__F3 Cell death signaling by the ER stress response/UPR ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC7886236__F3 Insulin-like factor-1 (IGF-1) signaling and the multiple pathway axis ENSG00000169047 ENSG00000146648 ENSG00000140443 PMC3673972__F10 Antioxidant and Anti-Inflammatory Effects in RAW264.7 Macrophages of Malvidin, a Major Red Wine Polyphenol ENSG00000183735 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC3037032__F4 The Chromatin Signaling Pathway: Diverse Mechanisms of Recruitment of Histone-Modifying Enzymes and Varied Biological Outcomes ENSG00000039537 ENSG00000173120 PMC5831137__F1 Dual-targeting Wnt and uPA Receptors Using Peptide Conjugated Ultra-small Nanoparticle Drug Carriers Inhibited Cancer Stem-Cell Phenotype in Chemo-Resistant Breast Cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8945028__F2 Manipulation of Meiotic Recombination to Hasten Crop Improvement ENSG00000051180 ENSG00000100206 ENSG00000054796 ENSG00000095002 PMC9437549__F2 Microbial lectome versus host glycolipidome: How pathogens exploit glycosphingolipids to invade, dupe or kill ENSG00000176597 ENSG00000008513 ENSG00000135454 ENSG00000111728 ENSG00000101638 ENSG00000183778 ENSG00000158470 ENSG00000115525 PMC9393754__F4 Hypoxia-inducible factor-1 alpha in multidrug-resistant breast cancer ENSG00000168036 ENSG00000057663 PMC9597307__F1 Venetoclax resistance and solutions ENSG00000239732 ENSG00000002330 ENSG00000137265 ENSG00000162772 ENSG00000168610 ENSG00000127616 PMC3408479__F8 Endoplasmic Reticulum Stress Stimulates p53 Expression through NFKB Activation ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC7298530__F2 Unique Energy-Saving Strategy during Hibernation Revealed by Multi-Omics Analysis in the Chinese Alligator ENSG00000291355 ENSG00000042832 ENSG00000128951 ENSG00000198951 ENSG00000198626 ENSG00000291507 ENSG00000163131 ENSG00000198576 ENSG00000165409 ENSG00000170893 ENSG00000005381 ENSG00000100365 ENSG00000040531 PMC8353059__F2 Emerging Role of PD-1 in the Central Nervous System and Brain Diseases ENSG00000291603 ENSG00000115415 ENSG00000156127 ENSG00000198793 ENSG00000105639 PMC8353059__F3 Emerging Role of PD-1 in the Central Nervous System and Brain Diseases ENSG00000115415 ENSG00000105639 PMC8972902__F4 Clinical and translational values of spatial transcriptomics ENSG00000011600 ENSG00000185664 ENSG00000197930 ENSG00000118785 ENSG00000160180 ENSG00000160182 ENSG00000160181 ENSG00000273686 ENSG00000001626 ENSG00000096006 ENSG00000254709 ENSG00000147894 PMC7294267__F1 Three mechanisms suggested for the effects of statins and ACEis/ARBs in preventing severe pulmonary disease in COVID-19 ENSG00000130234 ENSG00000150907 ENSG00000172936 ENSG00000091879 ENSG00000154188 PMC3214144__F1 HCMV promotes GBM pathogenesis ENSG00000087245 ENSG00000134853 ENSG00000100985 ENSG00000049768 PMC3998120__F4 Origins of Metastatic Traits ENSG00000291971 ENSG00000112715 ENSG00000162692 ENSG00000115165 ENSG00000121966 PMC3669032__F6 Canonical pathway analysis ENSG00000162889 ENSG00000175899 ENSG00000168610 PMC11201634__F4 An illustration of the specific Wnt signaling pathway associated inhibitors that have been studied in preclinical and clinical trials for pediatric tumors ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000102312 ENSG00000168036 PMC11201634__F2 Wnt/Beta-Catenin Signaling Pathway in Pediatric Tumors: Implications for Diagnosis and Treatment ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11201634__F1 Canonical Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6218864__F8 Simplified schematic of the effects of nephron-specific Jab1 deletion on the CUL3-KLHL3-WNK pathway ENSG00000126562 ENSG00000143867 ENSG00000146021 PMC5705551__F1 Major in vivo approaches for tolerance induction and suppression of inhibitor formation in hemophilia ENSG00000134982 ENSG00000186716 ENSG00000198793 ENSG00000049768 PMC6878006__F6 Predicted localization of proteins and biosynthetic pathways in Synechocystis ENSG00000070444 ENSG00000117525 ENSG00000182511 ENSG00000173599 ENSG00000137714 ENSG00000145020 PMC9709406__F6 Icotinib derivatives as tyrosine kinase inhibitors with anti-esophageal squamous carcinoma activity ENSG00000198793 ENSG00000146648 PMC8774233__F2 Metastatic Progression of Osteosarcomas: A Review of Current Knowledge of Environmental versus Oncogenic Drivers ENSG00000125398 ENSG00000137673 ENSG00000168214 ENSG00000122691 ENSG00000163914 ENSG00000102854 PMC8214786__F7 Dihydromyricetin ameliorates liver fibrosis via inhibition of hepatic stellate cells by inducing autophagy and natural killer cell-mediated killing effect ENSG00000168610 ENSG00000106546 PMC4845199__F1 Possible model to explain the involvement of AATF in mTOR pathway ENSG00000168209 ENSG00000275700 ENSG00000155792 PMC10454115__F4 Mechanisms of Pi, Tf, Td, and Cr in AS ENSG00000136869 PMC4660682__F10 Differential proteins in acute phase signaling pathway in DN summarized in this and previous studies ENSG00000185010 ENSG00000062485 PMC7350255__F8 Representation of the KEGG protein process in endoplasmic reticulum pathway ENSG00000291983 ENSG00000053501 ENSG00000128272 ENSG00000090402 ENSG00000150991 ENSG00000188404 ENSG00000198168 PMC8491019__F5 Regulatory network driving shoot lignification in rapidly growing bamboo ENSG00000105227 PMC7593769__F7 Model of the C. acnes-induced intracellular signaling pathways ENSG00000183735 ENSG00000164430 ENSG00000172936 PMC3268503__F6 The Chl branch.The first step of the Chl branch is the insertion of Mg2+ into Proto IX ENSG00000100473 ENSG00000170430 ENSG00000127948 PMC7230378__F5 Cytoscape analysis considering TRAIL and miR-106b-5p in the apoptosis pathway ENSG00000132906 ENSG00000140992 ENSG00000137275 ENSG00000153094 ENSG00000123104 ENSG00000171791 ENSG00000121879 ENSG00000221823 ENSG00000178607 ENSG00000163131 ENSG00000136848 ENSG00000120868 ENSG00000064012 ENSG00000026103 PMC7947610__F5 Abnormal T cell Activation in GCA ENSG00000115271 PMC3577635__F2 Biochemical pathways leading to resistance to small-molecule epidermal growth factor receptor (EGFR)-targeting drugs such as gefitinib and erlotinib in non-small-cell lung cancer (NSCLC) ENSG00000167601 ENSG00000121879 ENSG00000146648 PMC8670088__F4 Triangle Relationship Between Long Noncoding RNA, RIG-I-like Receptor Signaling Pathway, and Glycolysis ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000122299 PMC6923932__F4 The molecular network of differentially expressed proteins in CAVD generated by Ingenuity Pathway Analysis ENSG00000182718 ENSG00000114124 ENSG00000073331 ENSG00000113600 ENSG00000170390 ENSG00000027644 ENSG00000149054 ENSG00000159792 ENSG00000183783 ENSG00000145949 ENSG00000140691 ENSG00000100426 ENSG00000062485 PMC8670088__F3 Triangle Relationship Between Long Noncoding RNA, RIG-I-like Receptor Signaling Pathway, and Glycolysis ENSG00000183735 ENSG00000088888 PMC9130481__F2 Multiple roles of endocytosis and autophagy in intracellular remodeling during oocyte-to-embryo transition ENSG00000134982 ENSG00000111737 PMC5623854__F2 Non-apoptotic signaling pathway induced by CD95 ENSG00000291971 ENSG00000198793 ENSG00000124181 ENSG00000146648 ENSG00000064012 PMC5623854__F1 CD95L is a chemoattractant for inflammatory T cells and triple-negative breast cancer (TNBC) cells ENSG00000137673 ENSG00000149968 ENSG00000137845 ENSG00000146648 PMC12157604__F6 Neuropathic pain pathways of Glutamatergic neurons under Mor vs Sal (A) and Mor+Pro vs Mor (B) conditions PMC8835757__F6 Transcriptomic Profile of Canine DH82 Macrophages Infected by Leishmania infantum Promastigotes with Different Virulence Behavior ENSG00000177455 ENSG00000012048 ENSG00000070193 ENSG00000103479 ENSG00000113456 ENSG00000049130 ENSG00000002330 ENSG00000186716 ENSG00000104894 ENSG00000184371 ENSG00000135424 ENSG00000115232 PMC9271452__F3 Increased H3K27 trimethylation contributes to cone survival in a mouse model of cone dystrophy ENSG00000173171 ENSG00000112651 ENSG00000099800 PMC3556263__F1 Molecular pathways affected by CR and irradiation ENSG00000198793 ENSG00000140443 PMC5239434__F1 NADPH: new oxygen for the ROS theory of aging ENSG00000151376 ENSG00000065833 ENSG00000120254 ENSG00000105227 PMC8882093__F2 Helicobacter pylori and gastric cancer: a lysosomal protease perspective ENSG00000145824 ENSG00000108691 ENSG00000107562 ENSG00000161921 ENSG00000291971 ENSG00000277943 PMC5054901__F2 MiRNA function in the immune system ENSG00000040199 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC8004226__F6 Network of putative senolytic compounds with their biological targets ENSG00000177606 ENSG00000196591 ENSG00000087085 ENSG00000051180 PMC8895820__F2 Molecular environment and atypical function: What do we know about enzymes associated with Mucopolysaccharidoses? ENSG00000107485 PMC5529438__F8 Functional involvement of Hh signaling molecules in estrogen- mediated endometrial hyperplasia ENSG00000132646 ENSG00000168036 PMC10520974__F3 Noncoding RNAs as an emerging resistance mechanism to immunotherapies in cancer: basic evidence and therapeutic implications ENSG00000100253 ENSG00000183735 ENSG00000088888 ENSG00000167468 PMC10520974__F4 Regulatory mechanisms of lncRNAs in cancer cell antigen presentation ENSG00000224320 ENSG00000232326 ENSG00000291501 PMC7400772__F1 Immune evasion in EC ENSG00000102962 PMC5343938__F3 Role of the RIG-1-like Receptors (RLRs) signaling pathway in antitumor immunity ENSG00000183735 ENSG00000088888 ENSG00000164305 PMC4211382__F3 Summary of intravascular/extravascular Hb/heme clearance and cellular/tissue distribution ENSG00000177575 PMC5343938__F1 Toll-like receptors (TLRs) and TLR-mediated signaling pathway ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC8670088__F2 Triangle Relationship Between Long Noncoding RNA, RIG-I-like Receptor Signaling Pathway, and Glycolysis ENSG00000111537 ENSG00000125538 ENSG00000205683 PMC10520974__F7 Noncoding RNAs as an emerging resistance mechanism to immunotherapies in cancer: basic evidence and therapeutic implications ENSG00000182578 PMC8670088__F1 Triangle Relationship Between Long Noncoding RNA, RIG-I-like Receptor Signaling Pathway, and Glycolysis ENSG00000253352 PMC9408811__F4 Phytotherapeuthics Affecting the IL-1/IL-17/G-CSF Axis: A Complementary Treatment Option for Hidradenitis Suppurativa? ENSG00000172936 ENSG00000175104 ENSG00000115594 ENSG00000163702 PMC6627901__F5 Model for the oncogenic activation of the EGFR signaling pathway and response to therapeutic EGFR-blockade in basal HNSCC ENSG00000109321 ENSG00000124882 ENSG00000146648 PMC3261822__F3 IPA-based pathway analysis of differential expressed genes ENSG00000161647 ENSG00000106333 ENSG00000144597 ENSG00000182568 ENSG00000198610 ENSG00000163159 ENSG00000123104 ENSG00000134287 ENSG00000168615 ENSG00000103034 ENSG00000172183 ENSG00000103811 ENSG00000277571 ENSG00000108582 ENSG00000167772 ENSG00000073060 ENSG00000139515 ENSG00000136997 ENSG00000161533 ENSG00000006327 ENSG00000112742 PMC9408811__F2 Phytotherapeuthics Affecting the IL-1/IL-17/G-CSF Axis: A Complementary Treatment Option for Hidradenitis Suppurativa? ENSG00000162711 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC3437546__F2 HIF target genes encode proteins involved in critical aspects of cancer progression ENSG00000087245 ENSG00000169554 ENSG00000148926 ENSG00000091879 ENSG00000071564 ENSG00000124216 ENSG00000074800 ENSG00000109861 ENSG00000011422 ENSG00000134013 ENSG00000157227 ENSG00000163235 ENSG00000019549 ENSG00000164362 ENSG00000100985 ENSG00000154188 PMC7968419__F1 Schematic presentation of possible cross-linkages between PCOS and HT ENSG00000109163 ENSG00000104899 ENSG00000163599 ENSG00000138039 ENSG00000170893 ENSG00000049768 ENSG00000178919 PMC5743625__F2 Epithelial PGR regulates multiple signaling pathways in the endometrium and transuduce signals via uterine epithelial-stormal inteactions ENSG00000162552 ENSG00000082175 ENSG00000117425 ENSG00000164107 ENSG00000163501 ENSG00000179348 ENSG00000146648 PMC9281973__F1 Benefit–risk assessment of sonidegib and vismodegib in the treatment of locally advanced basal cell carcinoma ENSG00000128602 PMC2962956__F1 Toll-like receptor (TLR) signalling and inhibition by viral proteins ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC4039115__F5 Diffuse large B-cell lymphoma with combined TP53 mutation and MIR34A methylation: Another “double hit” lymphoma with very poor outcome? ENSG00000135446 ENSG00000136997 ENSG00000105810 ENSG00000171791 ENSG00000096717 PMC1769518__F1 Complement system consists of about 30 proteins that can be activated by 3 different cascades ENSG00000244731 ENSG00000166278 ENSG00000236625 PMC4486472__F2 Neural Tube Defects ENSG00000284320 ENSG00000228716 ENSG00000065911 ENSG00000100714 ENSG00000136371 ENSG00000163738 ENSG00000145020 ENSG00000178445 ENSG00000120254 ENSG00000116984 PMC2841246__F4 COX-2 inhibitors on apoptosis ENSG00000132906 ENSG00000002330 ENSG00000168036 ENSG00000168040 ENSG00000164305 PMC6001373__F12 Working model for the actions of HDAC1/2 in the regulation of nephrogenesis ENSG00000103449 ENSG00000135100 ENSG00000143867 ENSG00000196591 ENSG00000075891 PMC5346747__F7 Glypican-5 suppresses Epithelial-Mesenchymal Transition of the lung adenocarcinoma by competitively binding to Wnt3a ENSG00000154342 ENSG00000087245 ENSG00000122691 ENSG00000134982 ENSG00000179399 PMC2984599__F1 TP53 levels determine whether CDKN1A will orchestrate irreversible senescence or quiescence ENSG00000198793 ENSG00000124762 PMC12064795__F7 Schematic diagram for the mechanism of SYT7-ALDH1A3 axis mediated carcinogenesis in NPC ENSG00000184254 ENSG00000168610 ENSG00000011347 PMC3235896__F2 Transdifferentiation of bone-marrow-derived mesenchymal stem cells (MSCs) into the multiple skin component cells ENSG00000134853 ENSG00000189403 ENSG00000126353 PMC11891113__F3 Expression levels of genes in phenylpropanoid biosynthesis, flavonoid biosynthesis, and galactose metabolism pathways under different drought treatments (CK, D9, D12) in C ENSG00000115419 ENSG00000084774 PMC7708490__F7 Proposed mechanistic scheme: MELK is critical for metastasis, mitotic progression, and programmed death of LUAD ENSG00000137673 ENSG00000122691 ENSG00000170558 ENSG00000166851 PMC8840921__F3 Aplysia Neurons as a Model of Alzheimer’s Disease: Shared Genes and Differential Expression ENSG00000152495 PMC8840921__F2 Aplysia Neurons as a Model of Alzheimer’s Disease: Shared Genes and Differential Expression ENSG00000023445 ENSG00000173039 ENSG00000172936 PMC8166894__F3 Dendritic spine remodeling and plasticity under general anesthesia ENSG00000070831 PMC3305973__F2 Sixteen genes associated with enzastaurin response were established by pathway analyses and prediction of drug response using an eight-gene signature ENSG00000115648 ENSG00000171105 ENSG00000069869 PMC7022557__F1 PI3K-Akt signaling pathway ENSG00000198793 ENSG00000171791 PMC7527410__F1 SARS-CoV-2 viral entry to host cell pathway ENSG00000130234 ENSG00000184012 PMC3924811__F10 Mechanosignaling in Bone Health, Trauma and Inflammation ENSG00000168036 ENSG00000108821 PMC2860235__F7 FunCoup subnetwork of candidate cancer gene RPA1 surrounded by functionally coupled known cancer genes ENSG00000075856 ENSG00000132781 ENSG00000122512 ENSG00000072609 PMC4182853__F1 The current understanding of p38D MAPK signalling and activation ENSG00000284161 ENSG00000167658 ENSG00000184304 PMC5931255__F2 Hedgehog signaling pathway inhibitors ENSG00000164690 ENSG00000128602 PMC6128202__F1 Main signaling pathways affected in high-grade gliomas ENSG00000135446 ENSG00000198793 ENSG00000146648 ENSG00000196712 PMC3248275__F7 Developmental stage determines estrogen receptor alpha expression and non-genomic mechanisms that control IGF-1 signaling and mammary proliferation in mice ENSG00000169047 ENSG00000140443 PMC7780992__F1 Conceptual overview of potential mechanistic pathway of Aspergillus fumigatus recognition through pattern recognition receptors in dendritic cells to upregulate IL-10 production and to downregulate allergic hypersensitivity reactions ENSG00000172936 PMC6505497__F4 Sprouty2—a Novel Therapeutic Target in the Nervous System? ENSG00000157540 ENSG00000181788 ENSG00000291971 PMC7754343__F1 Simplified schematic of the kynurenine pathway ENSG00000105835 ENSG00000262635 ENSG00000188676 PMC7336380__F1 TLR signaling and domain organization of TLR8 ENSG00000174123 ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC3593900__F5 Schematic illustrating how TNF acts via the Wnt pathway leading to the development of the myofibroblast phenotype ENSG00000134982 ENSG00000168036 PMC4243360__F1 Pathways of apoptosis ENSG00000112367 ENSG00000171791 PMC6149803__F1 Mediating the death of dormant tumor cells ENSG00000105397 ENSG00000291971 ENSG00000168610 ENSG00000106546 PMC2515306__F1 Wnt signaling pathway and its inhibition by AB aggregates ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167074 PMC5419474__F10 NCA-1 and NCA-2 Ion Channels Function Downstream of Gq and Rho To Regulate Locomotion in Caenorhabditis elegans ENSG00000038382 ENSG00000133958 ENSG00000163914 PMC7594557__F11 Simplified overview of signaling from common types of DNA damage to the DDR and cell cycle checkpoint pathways ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000135446 ENSG00000123374 ENSG00000051180 ENSG00000105810 ENSG00000138385 ENSG00000139618 PMC4572916__F1 Differential effects of Calmodulin on two key K-Ras4B effector pathways ENSG00000159224 ENSG00000171540 ENSG00000146648 PMC4459530__F1 Unexpected Functions of NFKB during Germinal Center B-Cell Development: Implications for Lymphomagenesis ENSG00000104856 ENSG00000186716 ENSG00000173039 ENSG00000111321 PMC9533094__F1 Minimal residual disease in EGFR-mutant non-small-cell lung cancer ENSG00000186575 ENSG00000198793 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC8231866__F1 Welcome to the Family: Identification of the NAD+ Transporter of Animal Mitochondria as Member of the Solute Carrier Family SLC25 ENSG00000143799 ENSG00000187531 ENSG00000105835 ENSG00000291803 ENSG00000077463 ENSG00000142082 ENSG00000283100 ENSG00000157064 ENSG00000041880 ENSG00000124523 ENSG00000173614 ENSG00000122696 ENSG00000096717 ENSG00000089163 ENSG00000100372 PMC6591387__F2 Inflammasome regulatory network ENSG00000094631 ENSG00000162711 ENSG00000167207 ENSG00000081237 ENSG00000115267 ENSG00000091592 ENSG00000213341 ENSG00000148606 ENSG00000276561 ENSG00000283100 ENSG00000151702 ENSG00000183735 ENSG00000088888 ENSG00000103490 ENSG00000105397 ENSG00000125538 ENSG00000284099 ENSG00000255501 PMC8616422__F2 Bile Acid Receptors and the Gut–Liver Axis in Nonalcoholic Fatty Liver Disease ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC3870072__F4 Subnetwork 1 and 5 of 6 networks in vehicle group ENSG00000280831 ENSG00000019991 ENSG00000125740 ENSG00000253293 ENSG00000090402 ENSG00000291603 ENSG00000221914 ENSG00000168036 ENSG00000187714 ENSG00000105227 ENSG00000095585 ENSG00000115464 ENSG00000150681 ENSG00000112242 ENSG00000076928 ENSG00000148082 ENSG00000149273 ENSG00000132874 ENSG00000185591 ENSG00000140464 ENSG00000169375 ENSG00000196367 ENSG00000116745 ENSG00000126457 ENSG00000177954 ENSG00000143479 ENSG00000140807 ENSG00000160752 ENSG00000186716 ENSG00000120094 ENSG00000177606 ENSG00000023839 ENSG00000149480 PMC3870072__F3 Two reversing pathways between the vehicle and baicalin groups ENSG00000169291 ENSG00000070831 ENSG00000171540 ENSG00000081189 PMC8996985__F3 Transforming Growth Factor-Beta Orchestrates Tumour and Bystander Cells in B-Cell Non-Hodgkin Lymphoma ENSG00000170365 ENSG00000137834 PMC3870072__F5 Subnetworks 1, 2, and 4 of 9 networks in baicalin group ENSG00000111837 ENSG00000173039 ENSG00000075891 ENSG00000185591 ENSG00000132341 PMC4900586__F5 Molecular Portrait of Oral Tongue Squamous Cell Carcinoma Shown by Integrative Meta-Analysis of Expression Profiles with Validations ENSG00000128641 ENSG00000187608 ENSG00000058085 ENSG00000162493 ENSG00000163568 ENSG00000197565 ENSG00000091409 ENSG00000166670 ENSG00000068079 ENSG00000041982 ENSG00000011422 ENSG00000118785 ENSG00000149968 ENSG00000019549 ENSG00000112655 ENSG00000100985 PMC6780497__F4 Enriched extracellular matrix organization pathway in non-type subtype of bladder carcinoma cell lines ENSG00000053747 ENSG00000213949 ENSG00000130702 ENSG00000083444 ENSG00000115221 ENSG00000149294 ENSG00000150093 ENSG00000152952 ENSG00000166147 PMC7713309__F5 Ingenuity pathway analyses of the dendritic cell maturation pathway (A) and TREM-1 signaling pathway (B) at 72 h post-infection, and expression level of related genes (C) ENSG00000110944 ENSG00000162711 ENSG00000115008 ENSG00000011600 ENSG00000167207 ENSG00000100906 ENSG00000234852 ENSG00000150337 ENSG00000111321 ENSG00000091106 ENSG00000136695 ENSG00000106100 ENSG00000168811 ENSG00000158869 ENSG00000150782 ENSG00000226275 ENSG00000072694 ENSG00000179344 ENSG00000277263 ENSG00000142405 ENSG00000164400 ENSG00000136869 ENSG00000188130 PMC3013516__F8 The interaction between cPLA2A and TGFBsignaling pathways in hepatic cells ENSG00000105329 PMC9010412__F6 SNORD1C was upregulated in CRC, which activated the canonical Wnt/Beta-catenin pathway and promoted the development of cancer stem cells ENSG00000168036 PMC12250560__F4 Advances in Understanding Intestinal Homeostasis: Lessons from Inflammatory Bowel Disease and Monogenic Intestinal Disorder Pathogenesis ENSG00000167207 ENSG00000078747 PMC8526852__F1 Exploration of Pattern Recognition Receptor Agonists as Candidate Adjuvants ENSG00000172680 PMC5971462__F9 Smooth muscle cells differentiation process ENSG00000105329 PMC7346011__F8 The anti-inflammatory mechanism of P22077 ENSG00000125538 ENSG00000136869 ENSG00000175104 PMC2242658__F8 Wingless and integration site growth factor (WNT)-induced epidermal growth factor receptor (EGFR) transactivation ENSG00000291971 ENSG00000168036 ENSG00000104332 ENSG00000146648 ENSG00000125084 PMC12048993__F7 Macrophages with high expression of PD-1 inhibit their anti-tumor immune function ENSG00000168610 PMC6365644__F4 Differentially regulated metabolic fluxes and metabolites in gluconeogenesis (A), pentose phosphate pathway (B), TCA cycle (C), arginine biosynthesis pathways (D), and respiratory chain (E) under 2-mg/liter colistin treatment for 1 h ENSG00000122966 ENSG00000172005 PMC4063500__F2 Lithium’s autophagy regulation mechanism in various neuropsychiatric diseases ENSG00000198793 PMC3190105__F1 TLR-dependent and JAK/STAT-dependent signaling pathways in microglia ENSG00000174125 ENSG00000159128 ENSG00000115415 ENSG00000027697 ENSG00000172936 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC11631473__F2 Metabolic pathways for anabolism and catabolism of DAG in model yeast Saccharomyces cerevisiae ENSG00000083857 ENSG00000173599 PMC5606034__F5 GPR and HDAC co-regulation network related to epithelium metabolism ENSG00000063176 ENSG00000136960 ENSG00000247626 ENSG00000009830 ENSG00000189043 ENSG00000143198 ENSG00000138271 ENSG00000124181 PMC5606034__F4 GPR and HDAC co-regulation network related to epithelium growth ENSG00000094631 ENSG00000063176 ENSG00000109270 ENSG00000116991 ENSG00000100429 ENSG00000115825 ENSG00000124181 ENSG00000173327 ENSG00000108840 PMC11006178__F12 Proposed schematic model of METTL14 in TLR4-mediated innate immunity and promoting CSFV replication ENSG00000145388 ENSG00000198492 ENSG00000136869 PMC5226538__F3 ‘melanoma-enriched’ microRNA miR-4731-5p acts as a tumour suppressor ENSG00000145604 ENSG00000108055 ENSG00000135446 ENSG00000132646 ENSG00000123374 ENSG00000105810 ENSG00000277273 ENSG00000276876 PMC4096053__F2 Many functions of promyelocytic leukemia nuclear bodies and PML as a negative regulator of the PI3-kinase/Akt/mTOR pathway ENSG00000198793 ENSG00000140464 PMC4494966__F4 Organ-specific adaptive signaling pathway activation in metastatic breast cancer cells ENSG00000087510 ENSG00000282830 ENSG00000113196 ENSG00000169344 ENSG00000149930 ENSG00000140968 ENSG00000113140 ENSG00000104833 ENSG00000288292 ENSG00000184481 ENSG00000115828 ENSG00000115459 ENSG00000155307 ENSG00000154978 ENSG00000187566 ENSG00000149968 ENSG00000011028 ENSG00000152137 ENSG00000143412 ENSG00000188611 ENSG00000105483 ENSG00000127324 PMC7504721__F1 Complement is activated by three canonical pathways known as the classical pathway (CP), lectin pathway (LP), or alternative pathway (AP) ENSG00000039537 ENSG00000113600 ENSG00000288512 ENSG00000166278 ENSG00000116096 ENSG00000182326 PMC3810612__F6 Schematic diagrams of midsagittal sections through (A) the rainbow trout and (B) rat brains to summarize the contributions and interactions of the serotonergic and corticotropin-releasing factor (CRF) systems in the regulation of food intake ENSG00000163794 ENSG00000198576 PMC9640632__F1 Probabilistic model checking of cancer metabolism ENSG00000122966 ENSG00000172005 PMC6601390__F3 Molecular characteristics of steroid hormone receptors in endometriotic tissue ENSG00000082175 ENSG00000134533 PMC5085631__F6 Model showing how decreased expression of SRSF2 affects apoptotic pathways in renal cancer cells ENSG00000102871 ENSG00000049249 ENSG00000168040 ENSG00000258643 ENSG00000127191 ENSG00000028137 PMC9245023__F3 Microglial Inflammatory-Metabolic Pathways and Their Potential Therapeutic Implication in Major Depressive Disorder ENSG00000162711 ENSG00000125538 ENSG00000198793 ENSG00000163914 PMC6104123__F1 TGFB induces CD103 expression in tumor-specific T cells and participates in integrin bidirectional signaling PMC9245023__F1 Microglial Inflammatory-Metabolic Pathways and Their Potential Therapeutic Implication in Major Depressive Disorder ENSG00000080345 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC10142983__F6 Therapy-Resistant Acute Myeloid Leukemia Stem Cells Are Resensitized to Venetoclax + Azacitidine by Targeting Fatty Acid Desaturases 1 and 2 ENSG00000134824 ENSG00000149485 PMC3060778__F4 Comparative and demographic analysis of orangutan genomes ENSG00000162139 ENSG00000148488 ENSG00000049860 PMC8064692__F2 NRG/ErbB signaling and downstream signaling pathway ENSG00000169291 ENSG00000002330 ENSG00000110395 ENSG00000065361 ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000198793 ENSG00000158458 ENSG00000169752 ENSG00000178568 PMC8862564__F4 Germline specification from pluripotent stem cells ENSG00000087510 ENSG00000164736 ENSG00000147596 PMC5173082__F4 mTORC2/Akt pathway ENSG00000169047 ENSG00000168610 ENSG00000140443 PMC3838179__F11 Proposed model for the NOTCH-ROCK pathway and its biological significance ENSG00000148400 ENSG00000163914 ENSG00000067900 PMC10976354__F2 KEGG enrichment analysis of the SGNI targets ENSG00000132906 ENSG00000149311 ENSG00000142192 ENSG00000177606 ENSG00000171791 ENSG00000084774 PMC8914108__F1 New Insights Into Energy Substrate Utilization and Metabolic Remodeling in Cardiac Physiological Adaption ENSG00000198793 PMC4419619__F1 Modulation of Insulin-Like Growth Factor-1 Receptor and its Signaling Network for the Treatment of Cancer: Current Status and Future Perspectives ENSG00000169047 ENSG00000140443 PMC4375924__F5 Discordant and concordant gene expression in the PI3K-Akt-mTORC1 signaling cascade ENSG00000198793 ENSG00000155792 ENSG00000167965 ENSG00000104408 PMC6401644__F3 PIN1 acts at multiple levels of cooperating cellular pathways ENSG00000127445 ENSG00000148400 ENSG00000132478 ENSG00000109670 PMC10889501__F4 Postulated relationship between IL-1B/IL-1RA axis and autophagy signaling pathway in invasive bladder cancer ENSG00000198793 PMC8625891__F1 Type of Fat in the Diet Influences Regulatory Aminopeptidases of the Renin-Angiotensin System and Stress in the Hypothalamic-Pituitary-Adrenal Axis in Adult Wistar Rats ENSG00000170893 PMC9294202__F3 Crystallographic mining of ASK1 regulators to unravel the intricate PPI interfaces for the discovery of small molecule ENSG00000065613 ENSG00000156194 ENSG00000150244 ENSG00000118503 ENSG00000078747 ENSG00000050165 ENSG00000127191 PMC3886801__F1 STAT-3: A Molecular Hub for Signaling Pathways in Gliomas ENSG00000291971 ENSG00000138798 ENSG00000168610 ENSG00000155657 PMC3638038__F1 Pluripotent Stem Cells: Immune to the Immune system? ENSG00000134982 ENSG00000163599 ENSG00000112149 ENSG00000049768 PMC8198123__F2 Therapeutics Targeting the Core Apoptotic Machinery ENSG00000168040 ENSG00000026103 PMC8515747__F9 Investigation of anti-osteoporosis mechanisms of Rehmanniae Radix Preparata based on network pharmacology and experimental verification ENSG00000169291 ENSG00000171791 ENSG00000147654 ENSG00000146648 ENSG00000127948 ENSG00000171345 PMC3474542__F2 Nongenomic and genomic estrogen signaling pathways ENSG00000113070 ENSG00000146648 PMC3886801__F2 STAT-3: A Molecular Hub for Signaling Pathways in Gliomas ENSG00000099985 ENSG00000168610 ENSG00000155657 PMC9407007__F2 Endothelial Cell Dysfunction and Nonalcoholic Fatty Liver Disease (NAFLD): A Concise Review ENSG00000169245 ENSG00000108691 ENSG00000107562 ENSG00000161921 ENSG00000128917 ENSG00000125538 ENSG00000121966 PMC8193943__F2 Posttranslational Modifications and Related Molecular Mechanisms in Diabetic Nephropathy ENSG00000135655 ENSG00000137834 ENSG00000063978 ENSG00000123091 ENSG00000173039 ENSG00000076604 ENSG00000079999 PMC8193943__F1 Posttranslational Modifications and Related Molecular Mechanisms in Diabetic Nephropathy ENSG00000136807 ENSG00000137834 ENSG00000198742 ENSG00000132964 ENSG00000175104 PMC2936527__F1 Synthesizing and Salvaging NAD+: Lessons Learned from Chlamydomonas reinhardtii ENSG00000105835 ENSG00000278488 ENSG00000183077 PMC11997497__F8 Graphic model of dedifferentiation-immunosuppression loop formed by malignant cell and macrophage in ICCMalignant cells and macrophages in ICC are involved in a dedifferentiation-immunosuppression loop ENSG00000150782 ENSG00000104972 ENSG00000112715 ENSG00000274513 ENSG00000164104 PMC8283745__F2 Four categories of regulatory mechanisms for nucleic acid-sensing Toll-like receptors ENSG00000166428 ENSG00000239732 ENSG00000105612 ENSG00000120280 ENSG00000188056 ENSG00000110057 ENSG00000105223 ENSG00000198246 PMC6904658__F2 Probable immunoregulatory mechanisms mediated by gut microbiota as a consequence of faecal microbiota transplantation (FMT) in inflammatory bowel disease (IBD) ENSG00000049768 ENSG00000106546 PMC10926624__F2 Molecular mechanisms of Trp metabolism in gastric cancer ENSG00000164430 ENSG00000111799 ENSG00000176153 ENSG00000168610 ENSG00000106546 PMC10945197__F3 Function and mechanism of exosomes derived from different cells as communication mediators in colorectal cancer metastasis ENSG00000186810 ENSG00000107562 ENSG00000121966 PMC10945197__F1 Function and mechanism of exosomes derived from different cells as communication mediators in colorectal cancer metastasis ENSG00000107562 ENSG00000070831 ENSG00000196371 ENSG00000198793 ENSG00000135097 PMC7322951__F3 Accumulated lysosomal products on cellular and tissue homeostasis ENSG00000136869 PMC4422175__F1 Bile acid biosynthetic pathways ENSG00000198610 ENSG00000036530 ENSG00000180432 ENSG00000099377 ENSG00000122787 ENSG00000135929 PMC4422175__F5 Farnesoid X receptor (FXR) regulates enterohepatic circulation of bile acids ENSG00000138075 ENSG00000160867 ENSG00000167910 ENSG00000015520 ENSG00000173599 ENSG00000143921 PMC4422175__F8 Farnesoid X receptor (FXR) regulation of hepatic glucose and lipid metabolism in liver, adipocytes, and intestine ENSG00000130164 ENSG00000042832 ENSG00000160867 ENSG00000167910 ENSG00000166278 ENSG00000169174 ENSG00000026103 PMC8662531__F1 CGAS-STING signaling pathway ENSG00000183735 ENSG00000164430 PMC4422175__F7 Bile acid-activated S1P2 signaling ENSG00000291971 ENSG00000167910 ENSG00000169047 ENSG00000146648 PMC9104626__F3 Organophosphorus Pesticides as Modulating Substances of Inflammation through the Cholinergic Pathway ENSG00000002330 ENSG00000156026 ENSG00000168040 ENSG00000123268 PMC2147675__F1 Antimalarial therapy prevents Myc-induced lymphoma ENSG00000136997 ENSG00000145782 PMC6232724__F9 Schematic diagram of icariin regulation upon PA-induced insulin resistance ENSG00000169047 ENSG00000265972 ENSG00000168610 PMC8047476__F1 Psoriatic arthritis is a multifactor disease ENSG00000162594 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC5143759__F2 PIN1 dysregulation and targets in hepatocellular carcinoma ENSG00000127445 ENSG00000148400 ENSG00000198793 ENSG00000168036 PMC4167018__F7 Modulatory effects of low-dose H2O2 on the functions of pDCs ENSG00000239732 ENSG00000172936 ENSG00000112149 ENSG00000276561 PMC3079059__F1 Control of intracellular heme levels: Heme transporters and Heme oxygenases ENSG00000135776 ENSG00000144410 ENSG00000066926 ENSG00000126088 ENSG00000115657 PMC8226072__F1 Targeting Future Pandemics, a Case for De Novo Purine Synthesis and Basic Research ENSG00000128050 ENSG00000102967 ENSG00000084774 ENSG00000254550 PMC10815326__F7 Different patterns of inflammatory gene activation in cerebral cortex and cerebellum of Npc1−/− mice ENSG00000169245 ENSG00000107562 ENSG00000108688 ENSG00000163734 ENSG00000141458 ENSG00000136869 ENSG00000124875 ENSG00000105246 PMC7068213__F1 Graphical representation of the purine salvage pathway ENSG00000196839 ENSG00000291814 ENSG00000137198 ENSG00000119125 PMC3689995__F7 Dual functions of Smad2 in the maintenance of hESC and mEpiSC pluripotency ENSG00000165556 ENSG00000170365 ENSG00000096088 PMC5624830__F3 NOD1 and NOD2: beyond peptidoglycan sensing ENSG00000088888 ENSG00000167207 ENSG00000107201 ENSG00000100219 ENSG00000127191 ENSG00000106100 PMC10544979__F8 The MyD88 and TRIF signaling pathways and downstream responses by the protein-based adjuvants rSIP and FLH in APCs ENSG00000134982 ENSG00000172936 ENSG00000136869 PMC3899946__F2 Radiation-Induced Bystander Response: Mechanism and Clinical Implications ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000163624 ENSG00000123374 PMC5624830__F1 NOD1 and NOD2: beyond peptidoglycan sensing ENSG00000167207 ENSG00000106100 PMC7915460__F2 EphA2 signaling in normal (A) and cancer (B) cells ENSG00000142627 ENSG00000110395 ENSG00000070831 ENSG00000291971 ENSG00000163914 ENSG00000146648 PMC7407580__F1 Involvement of the CCL5/CCR5 axis in cancer progression ENSG00000178860 ENSG00000087245 ENSG00000108700 ENSG00000100985 ENSG00000168610 ENSG00000277943 PMC3711692__F5 Staufen-mediated mRNA decay PMC3064905__F3A Genomic revelations of a mutualism: the pea aphid and its obligate bacterial symbiont PMC9687456__F8 m6A Methylation Analysis Reveals Networks and Key Genes Underlying the Coarse and Fine Wool Traits in a Full-sib Merino Family ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000069482 ENSG00000186716 ENSG00000169047 PMC8924581__F2 Peroxisome Proliferator-Activated Receptor Gamma and Atherosclerosis: Post-translational Modification and Selective Modulators ENSG00000136807 ENSG00000135218 ENSG00000142611 ENSG00000160179 ENSG00000118520 ENSG00000116030 ENSG00000277273 ENSG00000096717 ENSG00000213523 PMC5666810__F2 Thrombin cleaves the amino-terminal domain of PAR1 and triggers intracellular signaling ENSG00000125538 ENSG00000198793 ENSG00000100985 PMC9525297__F8 Schematic presentation of  process involved in the inhibitory effect of SC on TNBC metastasis PMC7022396__F3 Metabolic pathways involved in the de novo synthesis from sugars of floral esters by H PMC4346630__F10 RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL ENSG00000162711 ENSG00000123144 ENSG00000137275 ENSG00000102871 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC4521753__F3 Identification of Oxygen-Responsive Transcripts in the Silage Inoculant Lactobacillus buchneri CD034 by RNA Sequencing ENSG00000197713 ENSG00000186063 ENSG00000154330 ENSG00000013375 PMC9424684__F11 Z1456467176 alleviates gouty arthritis by allosterically modulating P2X7R to inhibit NLRP3 inflammasome activation ENSG00000278718 ENSG00000162711 ENSG00000125538 ENSG00000172936 PMC8857305__F4 Mechanical regulation of bone remodeling ENSG00000170365 ENSG00000281324 ENSG00000169071 ENSG00000133110 ENSG00000162337 ENSG00000167941 ENSG00000150457 ENSG00000131023 PMC8857305__F3 Mechanical regulation of bone remodeling ENSG00000291971 ENSG00000163914 ENSG00000128602 ENSG00000103335 PMC3539742__F2 Autophagy and apoptosis- what’s the connection? ENSG00000112977 ENSG00000177606 ENSG00000168040 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC2930807__F4 Gene pathway analysis ENSG00000196296 ENSG00000151726 ENSG00000005339 ENSG00000077522 ENSG00000101470 ENSG00000174804 ENSG00000127955 ENSG00000173210 ENSG00000068976 ENSG00000162409 ENSG00000185231 ENSG00000100504 ENSG00000079435 ENSG00000124253 PMC8071514__F4 Role of the acetylation pathway in TAp73 regulation ENSG00000086991 ENSG00000143669 ENSG00000283100 PMC3403107__F8 The molecular pathway regulating Xenopus lung development ENSG00000143867 ENSG00000168484 ENSG00000134245 ENSG00000164920 PMC5602684__F1 Association of rs1801157 single nucleotide polymorphism of CXCL12 gene in breast cancer in Pakistan and in-silico expression analysis of CXCL12–CXCR4 associated biological regulatory network ENSG00000012048 ENSG00000107562 ENSG00000291971 ENSG00000138798 ENSG00000146648 ENSG00000121966 PMC11572133__F7 LPAR3 regulates EPO induction by hypoxia ENSG00000134086 ENSG00000198670 ENSG00000171517 PMC2820199__F4 Curcumin’s targets intracellular components implicated in cell proliferation signaling pathway in prostate cancer cells ENSG00000198793 ENSG00000123374 ENSG00000146648 PMC5270455__F4 Pathway derived from perturbation experiments ENSG00000123374 ENSG00000151617 ENSG00000077782 ENSG00000146648 ENSG00000140443 ENSG00000108840 PMC2820199__F3 Network of proteins, functional classes and cell processes modulated in prostate cancer cells after curcumin treatment ENSG00000100906 ENSG00000171791 ENSG00000146648 PMC5685770__F2 Therapeutic potential of cell cycle targeting in multiple myeloma ENSG00000134982 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000117399 PMC4606174__F2 Crosstalk between signaling pathways that lead to colorectal cancer progression ENSG00000281324 ENSG00000002330 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000146648 PMC7502316__F3 Alterations of Spermatozoa Proteomic Profile in Men with Hodgkin's Disease Prior to Cancer Therapy ENSG00000115484 ENSG00000165076 ENSG00000120438 ENSG00000146731 ENSG00000135624 ENSG00000291368 PMC2064427__F10 Schematic diagram illustrating the signaling mechanisms that control the bidirectional responses of the growth cone to BMP7 gradients ENSG00000106683 ENSG00000163914 PMC151138__F1 Signaling and transcriptional pathways of Th1 differentiation and the potential role of c-Rel ENSG00000138378 ENSG00000115415 ENSG00000134982 PMC4911353__F5 Interaction and expression pattern of SDEGs involved in canonical interferon signaling pathway in Mtb-infected mouse lungs with or without CC-11050 treatment ENSG00000068079 ENSG00000213928 ENSG00000111537 ENSG00000089127 ENSG00000115415 ENSG00000185201 ENSG00000033800 ENSG00000185885 ENSG00000230034 PMC8662531__F4 Aging and the cGAS-STING pathway ENSG00000183735 ENSG00000164430 ENSG00000105612 PMC3810296__F2 NLRP6 in Infection and Inflammation ENSG00000167207 ENSG00000163568 ENSG00000125538 ENSG00000174885 ENSG00000173039 ENSG00000172936 ENSG00000136869 ENSG00000106100 PMC9261412__F3 Recent Advances on Drug Development and Emerging Therapeutic Agents Through Targeting Cellular Homeostasis for Ageing and Cardiovascular Disease ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC6685071__F2 Impact of oncogenic pathways on evasion of antitumour immune responses ENSG00000123685 ENSG00000169245 ENSG00000081041 ENSG00000137033 ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000277943 PMC6610439__F11 NAD(H) recycles (not shown) in redox and dehydrogenase reactions and supplies mitochondria to generate ATP ENSG00000105835 PMC4884942__F1 Targeting Notch to overcome radiation resistance ENSG00000140564 ENSG00000148400 ENSG00000074181 ENSG00000138798 ENSG00000140287 ENSG00000184916 ENSG00000137845 PMC10505163__F9 Hallmarks of severe asthma and the possible role of the identified mRNAs by artificial intelligence methods ENSG00000011304 ENSG00000198793 ENSG00000172936 ENSG00000136869 PMC6056231__F9 Neural crest induction by Dkk2 and Wnt8 ENSG00000281324 ENSG00000162337 ENSG00000155011 ENSG00000019549 ENSG00000168036 PMC5595898__F6 Terpenoid biosynthesis in M ENSG00000160752 ENSG00000110921 ENSG00000152904 ENSG00000167508 PMC4741883__F8 Aberrant expression of homeobox gene SIX1 in Hodgkin lymphoma ENSG00000048052 ENSG00000107485 ENSG00000163132 ENSG00000269404 ENSG00000166484 ENSG00000126778 ENSG00000179348 ENSG00000081189 ENSG00000106829 PMC7843791__F2 Pi, Glutamine and the Essential Amino Acids in Modulating the Metabolism in Diabetes and Cancer ENSG00000147162 ENSG00000198408 ENSG00000174197 ENSG00000146733 PMC9034286__F6 Monitoring the induction of ferroptosis following dissociation in human embryonic stem cells ENSG00000151012 ENSG00000167468 ENSG00000163914 PMC7843791__F1 Pi, Glutamine and the Essential Amino Acids in Modulating the Metabolism in Diabetes and Cancer ENSG00000130957 ENSG00000078237 PMC9352111__F5 EIF2 signaling pathway: Male 2-year turquoise module ENSG00000148798 ENSG00000087085 PMC9352111__F4 Opioid signaling pathway: Males 7-week green module ENSG00000002330 ENSG00000157764 PMC9592740__F2 Kölliker’s organ-supporting cells and cochlear auditory development ENSG00000105193 ENSG00000198793 ENSG00000177606 ENSG00000118515 ENSG00000134871 ENSG00000170549 ENSG00000187244 ENSG00000143387 PMC7825156__F6 Metabolic disturbances in PD ENSG00000167910 ENSG00000099377 ENSG00000115271 ENSG00000135929 PMC7843791__F9 Pi, Glutamine and the Essential Amino Acids in Modulating the Metabolism in Diabetes and Cancer ENSG00000128272 ENSG00000059573 ENSG00000188158 ENSG00000100033 ENSG00000070669 ENSG00000084774 PMC7433406__F8 Neuroprotective Effects of Celastrol on Transient Global Cerebral Ischemia Rats via Regulating HMGB1/NFKB Signaling Pathway ENSG00000125538 ENSG00000189403 ENSG00000136869 ENSG00000131095 PMC8321659__F9 Scheme showing the main alterations found in aging neurons in vitro ENSG00000198793 ENSG00000141458 ENSG00000198911 PMC2957845__F6 Scheme of the Wnt signalling pathway including proteins from the RT-PCR array ENSG00000087095 ENSG00000112576 ENSG00000178585 ENSG00000281324 ENSG00000134982 ENSG00000175592 ENSG00000168036 ENSG00000106483 ENSG00000118971 ENSG00000169118 ENSG00000165879 ENSG00000102312 ENSG00000164093 ENSG00000119402 ENSG00000168772 PMC7564329__F6 Proposed molecular mechanism underlying increased neural excitabilities and susceptibility to ischemic injury caused by IL-4 deficiency ENSG00000144285 ENSG00000145863 ENSG00000113520 PMC5126841__F9 Schematic representation of the study ENSG00000111537 ENSG00000125538 PMC5337960__F7 Data-Driven Discovery of Extravasation Pathway in Circulating Tumor Cells ENSG00000111057 ENSG00000133937 ENSG00000134982 ENSG00000124491 ENSG00000010278 ENSG00000196628 ENSG00000157240 ENSG00000141232 ENSG00000041982 ENSG00000168214 ENSG00000038427 ENSG00000198742 ENSG00000136997 ENSG00000117335 ENSG00000100219 ENSG00000022267 ENSG00000087245 ENSG00000107404 ENSG00000169554 ENSG00000148400 ENSG00000167552 ENSG00000124216 ENSG00000170962 ENSG00000146648 ENSG00000115461 ENSG00000182253 ENSG00000019991 ENSG00000059804 ENSG00000166086 ENSG00000138798 ENSG00000170558 ENSG00000168036 ENSG00000105647 ENSG00000121879 ENSG00000092820 ENSG00000121966 ENSG00000179295 ENSG00000176692 ENSG00000283780 ENSG00000122862 ENSG00000148346 ENSG00000081237 ENSG00000113140 ENSG00000174804 ENSG00000176014 ENSG00000110324 ENSG00000168610 ENSG00000110042 ENSG00000071564 ENSG00000162733 ENSG00000078579 ENSG00000010810 ENSG00000156427 ENSG00000019549 ENSG00000100985 ENSG00000128602 ENSG00000114315 ENSG00000171608 PMC2698936__F2 Integrins in Lens Development and Disease ENSG00000291971 ENSG00000140443 PMC4741712__F4 An integrative approach for the identification of prognostic and predictive biomarkers in rectal cancer ENSG00000169228 ENSG00000140992 ENSG00000109332 ENSG00000065675 ENSG00000198053 ENSG00000169047 ENSG00000164305 ENSG00000141968 ENSG00000078967 ENSG00000105486 ENSG00000182247 ENSG00000163558 ENSG00000188404 ENSG00000138768 ENSG00000076662 ENSG00000198286 ENSG00000103266 ENSG00000143549 ENSG00000104343 ENSG00000170027 ENSG00000269335 ENSG00000109654 ENSG00000131508 ENSG00000152689 ENSG00000213341 ENSG00000170142 ENSG00000170035 ENSG00000072401 ENSG00000067606 ENSG00000010810 ENSG00000104671 ENSG00000100865 ENSG00000156113 ENSG00000155850 ENSG00000100196 PMC4058638__F1 Core phosphatases of the PI 3-Kinase pathway ENSG00000081913 ENSG00000040199 PMC5832853__F7 Pathways regulated by selected HPG axis-related hormone and protein in male reproduction as predicted by Pathway Ontology Database and KEGG Pathway Database ENSG00000109163 ENSG00000138039 ENSG00000196498 ENSG00000170498 ENSG00000131910 PMC3837380__F7 The Potential of 11C-acetate PET for Monitoring the Fatty Acid Synthesis Pathway in Tumors ENSG00000198793 ENSG00000169710 PMC7072466__F3 Expression profiles of key genes that are involved in the characteristic metabolite biosynthesis pathways in tea plants ENSG00000145321 ENSG00000084774 PMC6054847__F3 Effect on eukaryotic translation initiation factors (EIF2) signaling pathway in plasma of total mRNAs obtained from D-tocotrienol treatment of hepatitis C patients ENSG00000128272 ENSG00000120690 ENSG00000144895 PMC5832853__F8 Mechanism by which ECH enhances the sperm counts ENSG00000109163 ENSG00000115718 PMC10967111__F8 RTEL1/JNK/ELK-1 signaling-induced tumorigenesis of glioma ENSG00000164362 PMC11941992__F3 The mechanisms by which visceral obesity is a triggering factor for both systemic inflammation and insulin resistance (IR) ENSG00000162711 ENSG00000171105 ENSG00000134982 ENSG00000198793 ENSG00000136869 ENSG00000136859 PMC6970023__F1 Concept of the tubal precursors ENSG00000149311 ENSG00000175054 ENSG00000101752 PMC11941992__F2 Three main signal transduction pathways associated with GPR120/FFAR4 stimulation: —ANTI-INFLAMMATORY EFFECTS via beta-arrestin 2 (ARRB2) signaling in immune pro-inflammatory cells ENSG00000162711 ENSG00000159224 ENSG00000136869 ENSG00000026103 PMC4131434__F4 The enemy within: endogenous retroelements and autoimmune disease ENSG00000183735 ENSG00000164430 ENSG00000163565 PMC6789287__F7 Diagram of Ras/Raf/MAPK and PI3K/AKT/mTOR signaling pathways ENSG00000132906 ENSG00000002330 ENSG00000164305 PMC4741712__F2 An integrative approach for the identification of prognostic and predictive biomarkers in rectal cancer ENSG00000104343 ENSG00000109320 ENSG00000033800 ENSG00000173039 ENSG00000126457 ENSG00000027697 ENSG00000125347 ENSG00000276561 ENSG00000169245 ENSG00000111537 ENSG00000115415 ENSG00000177606 ENSG00000165156 ENSG00000168310 ENSG00000089737 PMC4445242__F3 Catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway ENSG00000104894 ENSG00000113263 ENSG00000124181 PMC7851912__F7 The NELFE/Beta-catenin/CSNK2B signaling axis in GC progression ENSG00000168036 PMC7471355__F3 Different roles of mTOR signaling in stress granules assembly ENSG00000198793 ENSG00000155792 PMC4116492__F1 Targeting FANCD2 for therapy sensitization ENSG00000149311 ENSG00000175054 ENSG00000144554 ENSG00000135446 PMC6282995__F1 Retrograde neurotrophic signalling organelles and their main destinations after arrival to the cell body ENSG00000005893 ENSG00000135404 PMC7898179__F6 Input-output signal processing plasticity of vagal motor neurons in response to cardiac ischemic injury ENSG00000146469 ENSG00000123454 ENSG00000137672 ENSG00000157005 PMC11663375__F3 The core regulatory pathways involved skin inflammaging (including NFKB/RIG-I, mTOR, TGFB, AMPK–SIRTs pathways) ENSG00000104856 ENSG00000278718 ENSG00000137834 ENSG00000162711 ENSG00000009724 ENSG00000187531 ENSG00000113600 ENSG00000291559 ENSG00000198793 ENSG00000155792 ENSG00000077463 ENSG00000166278 ENSG00000142082 ENSG00000135341 ENSG00000137845 ENSG00000057663 ENSG00000283100 ENSG00000124523 ENSG00000096717 ENSG00000089163 PMC4743686__F8 A proposed role of Coa6 in the mitochondrial copper delivery pathway to Cox2 ENSG00000168275 ENSG00000133028 ENSG00000284194 PMC7880663__F3 Role of astrocytes in post-traumatic synapse loss and repair ENSG00000149968 ENSG00000168610 ENSG00000154928 PMC3710315__F2 Identification of STAT target genes in adipocytes ENSG00000111537 ENSG00000099985 ENSG00000128342 PMC7688896__F2 Signaling pathways that regulate ADF/cofilin phosphorylation and dephosphorylation during LTP and LTD ENSG00000106683 ENSG00000070831 ENSG00000170558 ENSG00000168036 PMC11940282__F4 Hepcidin regulation in hepatocytes ENSG00000170365 ENSG00000137834 ENSG00000010704 ENSG00000106327 ENSG00000178752 ENSG00000177606 ENSG00000105697 ENSG00000136869 ENSG00000168610 ENSG00000079999 PMC8539850__F6 Decreased exosome-delivered miR-486-5p is responsible for the peritoneal metastasis of gastric cancer cells by promoting EMT progress ENSG00000115091 ENSG00000172005 ENSG00000145321 PMC8262738__F4 Mergeomics 2.0: a web server for multi-omics data integration to elucidate disease networks and predict therapeutics ENSG00000121410 ENSG00000147168 ENSG00000010810 ENSG00000163599 ENSG00000126353 ENSG00000121807 PMC7137223__F4 CeRNA network in this study ENSG00000140992 ENSG00000102053 ENSG00000178567 ENSG00000159784 ENSG00000186532 ENSG00000174989 ENSG00000166402 ENSG00000158195 ENSG00000130311 ENSG00000179364 ENSG00000108107 ENSG00000076108 ENSG00000185344 ENSG00000177674 ENSG00000140443 ENSG00000164916 ENSG00000146676 ENSG00000114554 ENSG00000136485 ENSG00000143549 ENSG00000128989 ENSG00000123091 ENSG00000132622 ENSG00000141576 ENSG00000100345 ENSG00000100228 ENSG00000198879 ENSG00000135077 ENSG00000114126 ENSG00000168792 ENSG00000169213 ENSG00000146054 ENSG00000182253 ENSG00000166794 ENSG00000144063 ENSG00000113504 ENSG00000124313 ENSG00000131899 ENSG00000292354 ENSG00000107902 ENSG00000204946 ENSG00000095777 ENSG00000186575 ENSG00000148773 ENSG00000183579 ENSG00000088247 ENSG00000221890 ENSG00000090376 ENSG00000273820 ENSG00000100376 ENSG00000281178 ENSG00000130749 ENSG00000143376 ENSG00000110917 ENSG00000129250 ENSG00000132300 ENSG00000180357 ENSG00000198792 ENSG00000120899 ENSG00000101255 ENSG00000171425 ENSG00000189114 ENSG00000185585 ENSG00000169155 ENSG00000198326 ENSG00000235718 ENSG00000080839 ENSG00000125869 ENSG00000171408 ENSG00000168490 ENSG00000198625 ENSG00000276340 PMC8262738__F3 Mergeomics 2.0: a web server for multi-omics data integration to elucidate disease networks and predict therapeutics ENSG00000020633 ENSG00000111321 ENSG00000175567 ENSG00000187266 ENSG00000010671 ENSG00000161955 ENSG00000111796 ENSG00000077150 ENSG00000213658 ENSG00000038427 ENSG00000188404 ENSG00000113263 ENSG00000281857 ENSG00000026103 ENSG00000275385 ENSG00000147168 ENSG00000198851 ENSG00000156738 ENSG00000113088 ENSG00000117322 ENSG00000154978 ENSG00000226275 ENSG00000117091 ENSG00000170458 ENSG00000010810 ENSG00000145649 ENSG00000184922 ENSG00000125245 PMC7137223__F3 Integrated protein-protein interaction network in present study ENSG00000140992 ENSG00000102053 ENSG00000178567 ENSG00000171466 ENSG00000186532 ENSG00000178809 ENSG00000174989 ENSG00000130517 ENSG00000188064 ENSG00000166402 ENSG00000087152 ENSG00000158195 ENSG00000121940 ENSG00000186300 ENSG00000196376 ENSG00000155428 ENSG00000074706 ENSG00000179364 ENSG00000108107 ENSG00000069667 ENSG00000152700 ENSG00000090615 ENSG00000196182 ENSG00000177674 ENSG00000140443 ENSG00000164916 ENSG00000146676 ENSG00000142408 ENSG00000143549 ENSG00000128989 ENSG00000132622 ENSG00000100345 ENSG00000116237 ENSG00000100228 ENSG00000166510 ENSG00000198879 ENSG00000054965 ENSG00000114126 ENSG00000168792 ENSG00000169213 ENSG00000182253 ENSG00000166794 ENSG00000113504 ENSG00000131899 ENSG00000292354 ENSG00000204946 ENSG00000215114 ENSG00000095777 ENSG00000186575 ENSG00000148773 ENSG00000183579 ENSG00000088247 ENSG00000221890 ENSG00000101236 ENSG00000130749 ENSG00000143376 ENSG00000128655 ENSG00000110917 ENSG00000129250 ENSG00000180357 ENSG00000120899 ENSG00000101255 ENSG00000171425 ENSG00000169155 ENSG00000198326 ENSG00000108671 ENSG00000235718 ENSG00000171408 ENSG00000128965 PMC8298376__F5 New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids ENSG00000226275 ENSG00000090402 ENSG00000002330 ENSG00000173039 ENSG00000135116 ENSG00000026103 PMC7137223__F2 MiRNAs-mRNAs regulatory network ENSG00000171466 ENSG00000178809 ENSG00000130517 ENSG00000188064 ENSG00000173218 ENSG00000166402 ENSG00000087152 ENSG00000186300 ENSG00000196376 ENSG00000155428 ENSG00000099308 ENSG00000278220 ENSG00000273274 ENSG00000108107 ENSG00000069667 ENSG00000185344 ENSG00000090615 ENSG00000196182 ENSG00000177674 ENSG00000164916 ENSG00000146676 ENSG00000142408 ENSG00000136485 ENSG00000143549 ENSG00000128989 ENSG00000132622 ENSG00000100345 ENSG00000116237 ENSG00000100228 ENSG00000166510 ENSG00000136731 ENSG00000198182 ENSG00000135077 ENSG00000054965 ENSG00000168792 ENSG00000169213 ENSG00000182253 ENSG00000124783 ENSG00000166794 ENSG00000144063 ENSG00000113504 ENSG00000107902 ENSG00000204946 ENSG00000095777 ENSG00000186575 ENSG00000148773 ENSG00000088247 ENSG00000221890 ENSG00000281178 ENSG00000101236 ENSG00000143376 ENSG00000110917 ENSG00000124493 ENSG00000100664 ENSG00000129250 ENSG00000180357 ENSG00000120899 ENSG00000171425 ENSG00000180432 ENSG00000183742 ENSG00000108671 ENSG00000080839 ENSG00000125869 ENSG00000171408 ENSG00000276340 PMC4167887__F1 Schematic overview over the creatine pathway PMC4642568__F2 RNA sequencing provides exquisite insight into the manipulation of the alveolar macrophage by tubercle bacilli ENSG00000104365 ENSG00000282905 ENSG00000109320 ENSG00000269335 ENSG00000213341 ENSG00000127191 ENSG00000101695 ENSG00000127445 ENSG00000088888 ENSG00000263528 ENSG00000188130 ENSG00000083799 ENSG00000145782 ENSG00000157111 PMC5499521__F1 Curious origins of Angioimmunoblastic T-Cell Lymphoma ENSG00000138378 ENSG00000010810 ENSG00000168610 PMC9656460__F1 Ferroptosis of Endothelial Cells in Vascular Diseases ENSG00000228716 ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000115107 ENSG00000127948 PMC11968978__F4 Crosstalk between Wnt and FGF signaling pathways ENSG00000168036 PMC11968978__F3 Overview diagram of Hedgehog pathway, Notch pathway and TGFB pathway ENSG00000128917 ENSG00000164690 ENSG00000273529 ENSG00000139549 ENSG00000184916 ENSG00000114315 ENSG00000128602 ENSG00000163501 ENSG00000090932 PMC11968978__F2 Non-canonical Wnt pathway signaling encompasses two major branches: the Wnt/PCP (Planar Cell Polarity) pathway and the Wnt/Ca2+ pathway ENSG00000087095 ENSG00000169071 ENSG00000100592 ENSG00000185483 PMC11968978__F1 Canonical Wnt pathway signaling ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000108375 ENSG00000146648 ENSG00000173273 ENSG00000166526 PMC2762706__F3 Hypoxia signaling pathway in DM patients 4d post-CPB/C ENSG00000134086 ENSG00000116030 ENSG00000112715 PMC11968978__F8 Wnt signaling pathway in various cancers, including colorectal cancer, hepatocellular carcinoma, lung cancers, chronic myeloid leukemia, triple-negative breast cancer, melanoma, and glioblastoma multiforme ENSG00000118518 ENSG00000162337 ENSG00000100592 ENSG00000106025 ENSG00000134982 ENSG00000186716 ENSG00000198793 ENSG00000104290 ENSG00000168036 ENSG00000004961 ENSG00000161202 ENSG00000196208 PMC5835104__F2 The RT2 Profiler Array gene expression data using Ingenuity Pathway Analysis (IPA) software ENSG00000100906 ENSG00000115415 ENSG00000125538 ENSG00000177606 ENSG00000157601 ENSG00000115267 ENSG00000164400 ENSG00000125347 ENSG00000175104 ENSG00000277943 ENSG00000164342 PMC7692350__F1 Molecular signaling pathway underlying NETs formation induced by different stimulus ENSG00000291971 ENSG00000136869 ENSG00000005381 PMC11968978__F6 Wnt signaling pathway plays a crucial role in modulating the immune microenvironment of tumors ENSG00000281324 ENSG00000162337 ENSG00000146678 ENSG00000049768 ENSG00000277943 PMC11968978__F5 Wnt signaling pathway in cancer stem cells (CSCs) ENSG00000281324 ENSG00000169071 ENSG00000106004 ENSG00000162337 ENSG00000134569 ENSG00000026508 ENSG00000185483 ENSG00000168036 ENSG00000108375 ENSG00000171791 ENSG00000166526 PMC1087506__F8 IRAK1 functions in the TLR and IL-1B pathway upstream of convergence with the TNFA pathway ENSG00000102871 ENSG00000177606 ENSG00000172936 ENSG00000175104 ENSG00000127191 PMC8914279__F1 Association of Viral Infection With the Development and Pathogenesis of Systemic Lupus Erythematosus ENSG00000151376 ENSG00000186716 ENSG00000112182 ENSG00000100219 PMC8305981__F2 Lysophospholipid Metabolism in Chronic Myelogenous Leukemia Stem Cells ENSG00000168036 ENSG00000198670 ENSG00000102886 PMC11968978__F9 Small molecule therapeutic drug map targeting all parts of the Wnt pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000102312 ENSG00000168036 ENSG00000108375 ENSG00000166278 ENSG00000166526 PMC4157753__F1 Retinal degeneration in animal models with a defective visual cycle ENSG00000121207 ENSG00000116745 ENSG00000197713 ENSG00000198691 PMC4882250__F5 Characterizing strain variation in engineered E. coli using a multi-omics based workflow ENSG00000197713 ENSG00000166816 ENSG00000062485 PMC7884239__F1 Role of ACE (angiotensin-converting enzyme)-2 in the pathogenesis of coronavirus disease 2019 (COVID-19) ENSG00000130234 PMC11802338__F3 Advances in the Study of Necroptosis in Vascular Dementia: Focus on Blood–Brain Barrier and Neuroinflammation ENSG00000168404 ENSG00000285379 ENSG00000247077 PMC11802338__F2 TNF‐A/TNFR1 mediates the major signaling pathway of necroptosis ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC3356006__F2 Central regulation of leptin signaling, autonomic innervation of the adipocyte and Beta-cell, and the starvation response ENSG00000042832 PMC12250049__F1 Hippo signaling pathway ENSG00000197905 ENSG00000114978 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC8226607__F1 Neuroprotection in Glaucoma: NAD+/NADH Redox State as a Potential Biomarker and Therapeutic Target ENSG00000105835 ENSG00000278488 PMC10040812__F8 Signaling protein GIV/Girdin mediates the Nephrin-dependent insulin secretion of pancreatic islet B cells in response to high glucose ENSG00000291971 PMC5348403__F4 Dapper homolog 1 alpha suppresses metastasis ability of gastric cancer through inhibiting planar cell polarity pathway ENSG00000004975 ENSG00000213949 ENSG00000259207 ENSG00000076706 ENSG00000100985 ENSG00000164171 ENSG00000112715 PMC6896004__F9 A proposed pathway of DOCK1 in the regulation of growth and motility of CLBC cells ENSG00000160208 PMC5405508__F6 Network analysis of apoptotic genes modulated in response to V3000 and V3034 infections in spleen at 24 h pi ENSG00000197747 ENSG00000148346 ENSG00000157933 ENSG00000157764 ENSG00000204103 ENSG00000182568 ENSG00000089127 ENSG00000221914 ENSG00000169756 ENSG00000023287 ENSG00000163565 ENSG00000196154 ENSG00000118816 ENSG00000099194 ENSG00000129351 ENSG00000126803 ENSG00000137077 ENSG00000113532 ENSG00000080166 ENSG00000122779 ENSG00000009413 ENSG00000186469 PMC5405508__F8 Network analysis of inflammatory genes modulated in response to V3000 and V3034 infections in brain ENSG00000288411 ENSG00000142627 ENSG00000099985 ENSG00000100906 ENSG00000162692 ENSG00000124664 ENSG00000089289 PMC9121494__F1 Advances in the Study of Circadian Genes in Non-Small Cell Lung Cancer ENSG00000069667 PMC12104300__F2 Interactions of the Eph/ephrin system in adenoid cystic carcinoma (AdCC) ENSG00000142627 ENSG00000169242 PMC5405508__F7 Network analysis of inflammatory genes modulated in response to V3000 and V3034 infections in spleen ENSG00000182718 ENSG00000224320 ENSG00000171049 ENSG00000230034 PMC12104300__F1 Eph/ephrin signaling in oral squamous cell carcinoma (OSCC): regulatory pathways, tumor progression, and therapeutic implications ENSG00000284816 ENSG00000196411 ENSG00000142627 ENSG00000106123 ENSG00000116106 ENSG00000243364 ENSG00000198793 ENSG00000135333 ENSG00000143590 ENSG00000167508 ENSG00000070886 ENSG00000146648 PMC6440158__F9 A working model of circPPP1R12A-73aa on promoting tumor pathogenesis and metastasis of CC via activating Hippo-YAP signaling pathway ENSG00000150457 ENSG00000131023 PMC9121494__F2 Advances in the Study of Circadian Genes in Non-Small Cell Lung Cancer ENSG00000143799 ENSG00000111602 ENSG00000141551 ENSG00000198793 ENSG00000112562 ENSG00000132326 ENSG00000168036 PMC7780023__F4 TET2: A cornerstone in normal and malignant hematopoiesis ENSG00000175104 ENSG00000168610 PMC2933229__F3 The Proneural Molecular Signature Is Enriched in Oligodendrogliomas and Predicts Improved Survival among Diffuse Gliomas ENSG00000136997 ENSG00000205927 ENSG00000162772 PMC4538774__F4 Representation of the adherens junction pathway map from KEGG ENSG00000087095 ENSG00000171105 ENSG00000070831 ENSG00000291971 ENSG00000140575 ENSG00000168036 ENSG00000136153 ENSG00000077782 ENSG00000140443 PMC3367865__F3 Molecular Biology of Lung Cancer: Clinical Implications ENSG00000068028 ENSG00000157404 ENSG00000198793 ENSG00000146648 ENSG00000196712 PMC8912576__F2 Mining of Potential Gene Resources for Breeding Nutritionally Improved Maize ENSG00000173599 ENSG00000198670 PMC3367865__F5 Molecular Biology of Lung Cancer: Clinical Implications ENSG00000002330 ENSG00000135446 ENSG00000136997 ENSG00000123374 ENSG00000105810 ENSG00000171791 PMC3367865__F4 Molecular Biology of Lung Cancer: Clinical Implications ENSG00000002330 ENSG00000163235 ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC3366440__F1 Protective and pathogenic functions of Th17 cells ENSG00000112116 ENSG00000226275 ENSG00000049768 ENSG00000112115 ENSG00000168610 PMC4855030__F5 Interaction network of innate immunity related proteins ENSG00000108298 ENSG00000065978 ENSG00000066044 ENSG00000114416 ENSG00000143933 ENSG00000129351 ENSG00000215301 ENSG00000155363 PMC7524833__F1 Interleukin-2-inducible T cell kinase plays a central role in the signal transduction of the T cell receptor ENSG00000213658 ENSG00000134982 ENSG00000137265 ENSG00000113263 ENSG00000124181 ENSG00000141968 PMC3896120__F8 Schematic diagram of EGFR-invadopodia signaling pathways altered by Abl inhibition in HNSCC ENSG00000291971 ENSG00000113070 ENSG00000146648 PMC5992580__F1 Gene clusters identified via gene interaction analysisLines indicate a physical interaction, as assigned by the GeneMANIA plugin for Cytoscape ENSG00000083093 ENSG00000169756 ENSG00000120889 ENSG00000110274 ENSG00000139618 ENSG00000175054 ENSG00000104320 ENSG00000204843 ENSG00000100813 ENSG00000095002 ENSG00000064012 ENSG00000171560 ENSG00000253729 PMC5395663__F1 Mesenchymal-­epithelial interactions during digestive tract development and epithelial stem cell regeneration ENSG00000165556 ENSG00000137273 ENSG00000125398 ENSG00000131668 ENSG00000107485 ENSG00000103241 ENSG00000164690 ENSG00000104332 PMC5833418__F9 Summary of the mechanism of NCK1-AS1 in CC cells ENSG00000132646 ENSG00000185591 PMC7190872__F1 Toll-like receptor pathways ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC7190872__F2 Crosstalk between TLR4, NLRP3 inflammasome, and complement promotes neuroinflammation in Alzheimer's disease ENSG00000162711 ENSG00000125538 ENSG00000172936 ENSG00000150455 ENSG00000175104 PMC7072681__F1 Growth factors, such as vascular endothelial growth factor (VEGF), epidermal growth factor (EGF) and fibroblast growth factor (FGF) bind receptor tyrosine kinases (RTKs) on the cell surface ENSG00000135446 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8572559__F2 JAK–STAT pathway: an emerging target for cardiovascular disease in rheumatoid arthritis and myeloproliferative neoplasms ENSG00000168610 PMC3275500__F1 The Ras-MAPK and TGFB pathways PMC6234768__F6 Mechanistically distinct regulation of VEGF secretion in MDA-MB-231 TNBC and T47D (ER+/PR+/HER2-) cells ENSG00000099985 ENSG00000185591 ENSG00000128342 PMC3367865__F6 Molecular Biology of Lung Cancer: Clinical Implications ENSG00000106571 ENSG00000134982 ENSG00000114315 ENSG00000128602 PMC3124653__F1 Systems pharmacology assessment of the 5-fluorouracil pathway ENSG00000228716 ENSG00000188641 ENSG00000128951 ENSG00000109320 ENSG00000136877 ENSG00000167325 ENSG00000161513 ENSG00000171848 ENSG00000147647 ENSG00000137563 ENSG00000167900 ENSG00000143179 PMC11215755__F3 Signalling and epigenetic mechanisms limiting the efficacy of PI3K inhibitors ENSG00000012048 ENSG00000124102 ENSG00000140992 ENSG00000109452 ENSG00000135446 ENSG00000105810 PMC3124653__F6 Systems pharmacology assessment of the 5-fluorouracil pathway ENSG00000228716 ENSG00000188641 ENSG00000128951 ENSG00000109320 ENSG00000136877 ENSG00000167325 ENSG00000161513 ENSG00000171848 ENSG00000147647 ENSG00000137563 ENSG00000167900 ENSG00000143179 PMC7886970__F3 CD40/CD40L signal pathways ENSG00000104856 ENSG00000291971 ENSG00000082512 ENSG00000056558 ENSG00000131323 ENSG00000105639 ENSG00000175104 ENSG00000127191 ENSG00000168610 PMC11215755__F1 PI3K pathway in non-malignant cells and cancer ENSG00000140992 PMC2697682__F1 Interaction of AEA with CB and TRPV1 receptors and its metabolism by FAAH and COX-2 ENSG00000117480 ENSG00000196689 PMC9661339__F2 NLRP3 Inflammasome in Parkinson’s Disease and Therapeutic Considerations ENSG00000162711 ENSG00000135218 ENSG00000136869 PMC9120845__F2 Aberrations in the Cross-Talks Among Redox, Nuclear FactorKB, and Wnt/Beta-Catenin Pathway Signaling Underpin Myalgic Encephalomyelitis and Chronic Fatigue Syndrome ENSG00000277571 ENSG00000174358 ENSG00000277263 ENSG00000164093 ENSG00000121053 ENSG00000127948 ENSG00000167419 PMC9120845__F1 Aberrations in the Cross-Talks Among Redox, Nuclear FactorKB, and Wnt/Beta-Catenin Pathway Signaling Underpin Myalgic Encephalomyelitis and Chronic Fatigue Syndrome ENSG00000104856 ENSG00000281324 ENSG00000162337 ENSG00000044115 ENSG00000140575 ENSG00000183762 ENSG00000168036 ENSG00000110651 ENSG00000121807 ENSG00000163631 ENSG00000104870 ENSG00000177455 ENSG00000277571 ENSG00000130234 ENSG00000188157 ENSG00000113558 ENSG00000115138 ENSG00000277263 ENSG00000189403 ENSG00000164400 ENSG00000136869 ENSG00000082556 ENSG00000277401 ENSG00000169218 ENSG00000138795 ENSG00000100906 ENSG00000292149 ENSG00000115590 ENSG00000110324 ENSG00000168040 ENSG00000127191 ENSG00000132693 ENSG00000019582 ENSG00000174358 ENSG00000170458 ENSG00000164093 ENSG00000243646 ENSG00000166603 ENSG00000168646 ENSG00000146648 ENSG00000028137 PMC7171049__F6 MiR-29c alleviates renal fibrosis via TPM1-mediated suppression of the Wnt/Beta-catenin pathway ENSG00000105329 ENSG00000134982 ENSG00000168036 ENSG00000140416 PMC5564444__F1 DNA damage and its links to neurodegeneration ENSG00000143799 ENSG00000105486 ENSG00000132646 ENSG00000039650 ENSG00000137074 ENSG00000042088 PMC9584744__F2 Effect of Liraglutide on Serum TSH Levels in Patients with NAFLD and its Underlying Mechanisms ENSG00000041982 ENSG00000002330 ENSG00000174197 PMC4523383__F1 Synthesis of estrogen, progesterone and testosterone from cholesterol ENSG00000108786 ENSG00000203857 PMC9393179__F3 Favorable impacts of silibinin polyphenols as adjunctive therapy in reducing the complications of COVID-19: A review of research evidence and underlying mechanisms ENSG00000111537 ENSG00000125538 ENSG00000184216 PMC6468558__F2 Summary and functional network target analysis of ginsenoside Rb1, which exerts significantly anti-obesity, anti-hyperglycemic, and anti-diabetic effects on diabetes via multiple links across regulatory mechanisms and multi-target effects ENSG00000139687 PMC5958082__F2 ADT DEGs enriched in integrin signaling pathway-associated transcripts ENSG00000164291 PMC7918591__F4 Crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle pathway (CETCH pathway) ENSG00000108960 PMC4355473__F2 Change in TNFR1 signaling pathway in 3 h, 12 h, and 24 h groups after cerebral ischemia-reperfusion injury ENSG00000102871 ENSG00000168040 ENSG00000115317 PMC7075814__F3 Synthesis, release, and activation of TGFB signaling via the canonical pathway ENSG00000135605 PMC4727203__F1 Regulation of actin cytoskeleton pathway ENSG00000070388 ENSG00000172830 ENSG00000172680 ENSG00000175866 ENSG00000102606 ENSG00000070831 ENSG00000105550 ENSG00000134982 ENSG00000138798 ENSG00000138443 ENSG00000181104 ENSG00000158195 ENSG00000115904 ENSG00000196468 ENSG00000100485 ENSG00000141298 ENSG00000136002 ENSG00000180210 ENSG00000169750 ENSG00000126458 ENSG00000133818 ENSG00000172380 ENSG00000157764 ENSG00000102466 ENSG00000078579 ENSG00000156427 ENSG00000115266 ENSG00000134853 ENSG00000015285 ENSG00000114279 PMC6215844__F2 Iron and inflammatory signaling to hepcidin ENSG00000170365 ENSG00000010704 ENSG00000106327 ENSG00000187045 ENSG00000105697 ENSG00000168610 PMC7075814__F4 Signaling via the non-canonical pathway of TGFB ENSG00000198742 ENSG00000198793 ENSG00000175104 PMC524242__F1 Proposed schematic of chemokine-induced traffic and activation of DCs following DNA vaccination with plasmid-encoded Flt3L and MIP-1A ENSG00000134982 ENSG00000126353 ENSG00000112149 PMC6280292__F8 Antitumor effects of emodin and chrysophanic acid ENSG00000198793 ENSG00000185591 ENSG00000146648 PMC2694412__F6 Somatic mutations affect key pathways in lung adenocarcinoma ENSG00000149311 ENSG00000171105 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000146648 ENSG00000139687 ENSG00000196712 PMC8318568__F2 An Ecological Basis for Dual Genetic Code Expansion in Marine Deltaproteobacteria ENSG00000145321 PMC9294349__F2 Endothelial Cells as a Key Cell Type for Innate Immunity: A Focused Review on RIG-I Signaling Pathway ENSG00000183735 ENSG00000088888 ENSG00000187608 ENSG00000125538 ENSG00000276561 PMC4671321__F5 Predicted model for the action of GSK3B in buffalo embryonic stem ( ES ) cells ENSG00000168036 ENSG00000128342 PMC8261484__F1 NAD+ synthesis pathways ENSG00000164638 ENSG00000174358 ENSG00000105835 ENSG00000162882 ENSG00000221955 ENSG00000278488 ENSG00000262217 ENSG00000112759 ENSG00000183077 ENSG00000172940 ENSG00000198246 PMC5653760__F6 Resveratrol has multiple biological functions that are relevant for AD ENSG00000142192 ENSG00000101871 ENSG00000198793 ENSG00000137845 PMC8096869__F2 Proposed stem cell concept for the development of leiomyomas ENSG00000184634 ENSG00000026508 ENSG00000168036 ENSG00000174059 PMC12250459__F4 Neuroprotective mechanisms of AOF ENSG00000002330 ENSG00000291971 ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000162924 ENSG00000175104 PMC7594413__F2 The MAPK pathway is here shown ENSG00000157764 PMC9301111__F2 Uncovering the Underlying Mechanisms of Ketamine as a Novel Antidepressant ENSG00000284161 ENSG00000167658 ENSG00000196470 ENSG00000178568 PMC6704159__F7 The cooperation between M and P proteins to inhibit different Jak-Stat-pathway steps ENSG00000187608 ENSG00000105397 ENSG00000115415 PMC6024232__F2 The pathway of acylceramide synthesis in keratinocytes ENSG00000118402 ENSG00000171954 ENSG00000154227 ENSG00000066322 ENSG00000119537 PMC5245686__F2 Metabolomics and Metabolic Diseases: Where do we stand? ENSG00000173599 ENSG00000079432 PMC4928174__F2 Canoncial and non-canonical Reelin signaling ENSG00000170558 ENSG00000173406 PMC3491089__F4 Schematic representation which shows possible mechanisms of action by D- and Gamma-tocopherol in multiple signaling pathways involved in mammary carcinogenesis ENSG00000132906 ENSG00000135446 ENSG00000132646 ENSG00000105810 ENSG00000171791 ENSG00000164305 ENSG00000079999 PMC4928174__F1 Core Reelin signaling pathway ENSG00000170558 PMC7696795__F1 Activation of JNK by proinflammatory cytokines TNFA and IL-17 leading to autoimmune arthritis ENSG00000102871 ENSG00000175104 ENSG00000127191 PMC10869406__F5 Relationship between major genes and the PI3K/AKT/mTOR signaling pathway ENSG00000114993 ENSG00000019582 ENSG00000197081 ENSG00000175220 ENSG00000198793 ENSG00000143933 ENSG00000145349 ENSG00000161960 PMC8935230__F8 Melatonin reverses tumor necrosis factor-alpha-induced metabolic disturbance of human nucleus pulposus cells via MTNR1B/GAi2/YAP signaling ENSG00000139219 ENSG00000134640 ENSG00000157766 ENSG00000131023 ENSG00000127948 PMC5256616__F4 RGS6 in central nervous system diseases PMC5964982__F2 Notch signaling pathway ENSG00000140564 ENSG00000168214 ENSG00000148400 ENSG00000074181 ENSG00000137845 PMC5256616__F6 Schematic illustrating the G protein-independent role of RGS6 in doxorubicin-induced apoptosis and antiproliferative signaling in the breast ENSG00000149311 ENSG00000136048 PMC8263635__F11 ELOVL2: a novel tumor suppressor attenuating tamoxifen resistance in breast cancer ENSG00000157554 ENSG00000105329 ENSG00000197977 ENSG00000167965 ENSG00000104081 PMC9537819__F1 Dietary meat mutagens intake and cancer risk: A systematic review and meta-analysis ENSG00000140505 ENSG00000146247 PMC8269395__F5 Emerin Represses STAT3 Signaling through Nuclear Membrane-Based Spatial Control ENSG00000009709 ENSG00000122180 ENSG00000168610 PMC3459479__F1 RAS pathway and its correlation with RASopathies ENSG00000157764 ENSG00000110395 ENSG00000115904 ENSG00000166068 ENSG00000108061 ENSG00000062485 PMC2706609__F1 ERK1/2 pathway in airway epithelial cell responses to cigarette smoke ENSG00000138798 ENSG00000185591 ENSG00000146648 PMC12214337__F12 Comprehensive Computational Assessment of SNAI1 and SNAI2 in Gastric Cancer: Linking EMT, Tumor Microenvironment, and Survival Outcomes ENSG00000162512 ENSG00000019549 PMC8054829__F1 Type I interferon in the pathogenesis of systemic lupus erythematosus ENSG00000138378 ENSG00000172936 ENSG00000276561 PMC8170976__F9 Parkinson mice show functional and molecular changes in the gut long before motoric disease onset ENSG00000282830 ENSG00000277586 ENSG00000244687 ENSG00000079689 ENSG00000241553 ENSG00000177556 ENSG00000220205 ENSG00000182253 ENSG00000140416 PMC3739200__F1 Three important components in the regeneration of the cavernous nerve: brain-derived neurotrophic factor, vascular endothelial growth factor and the JAK/STAT signaling pathway PMC6769444__F5 Proteasome pathway mapping of altered genes in DLD-1-miR-21 cells ENSG00000197713 ENSG00000111537 ENSG00000163902 ENSG00000198576 ENSG00000143839 ENSG00000175643 ENSG00000132963 PMC7192829__F2 Regulatory mechanisms involved in vitamin D-induced autophagy ENSG00000174125 ENSG00000198793 ENSG00000112561 PMC1449579__F1 F igure 1.— ENSG00000132646 ENSG00000070950 PMC7710911__F2 ACAs and CENP-B: CENP-B bound to CCR3 ENSG00000125817 ENSG00000291971 ENSG00000113070 ENSG00000183625 ENSG00000146648 PMC7870526__F2 Metabolic regulation of lung myofibroblast activation ENSG00000180210 ENSG00000092621 ENSG00000135069 ENSG00000146733 ENSG00000115419 ENSG00000159399 PMC12061715__F4 Analysis of the mechanism of skeletal muscle atrophy from the pathway of decreased protein synthesis ENSG00000128272 ENSG00000116717 ENSG00000168610 PMC4429297__F4 Network-Based Identification of Smoking-Associated Gene Signature for Lung Cancer ENSG00000075223 ENSG00000112242 ENSG00000138798 ENSG00000167972 ENSG00000197563 ENSG00000095713 ENSG00000133740 ENSG00000291917 ENSG00000146648 PMC12061715__F2 Detailed mechanism of GSK3B involvement in reduced protein synthesis ENSG00000169047 ENSG00000168036 ENSG00000164327 PMC6382829__F5 ZINC24469384 regulates genes involved in P53 and STAT signaling pathways ENSG00000172216 ENSG00000198793 ENSG00000177606 PMC7079998__F3 STAT3 roles in viral infection: antiviral or proviral? ENSG00000291971 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC9096207__F4 Transcoelomic Ecosystem and Epithelial Ovarian Cancer Dissemination ENSG00000163464 ENSG00000135218 ENSG00000121807 ENSG00000168610 PMC3480720__F1 Innate immune signals during B ENSG00000239732 ENSG00000167207 ENSG00000115415 ENSG00000196839 ENSG00000172936 ENSG00000150455 ENSG00000106100 PMC7714782__F1 Response of methionine metabolism in the liver ENSG00000116984 PMC9096207__F3 Transcoelomic Ecosystem and Epithelial Ovarian Cancer Dissemination ENSG00000072571 ENSG00000019991 ENSG00000133110 ENSG00000074181 ENSG00000026508 PMC9096207__F2 Transcoelomic Ecosystem and Epithelial Ovarian Cancer Dissemination ENSG00000102962 ENSG00000133110 ENSG00000168610 PMC7714782__F3 Metabolism of methionine in viral infections of hepatitis B and C ENSG00000151224 ENSG00000115415 ENSG00000033800 ENSG00000126457 PMC1449579__F5 F igure 5.— ENSG00000132646 ENSG00000070950 PMC2786169__F4 Topology of leukemia-related BCR-ABL pathway ENSG00000002330 ENSG00000115415 ENSG00000186716 ENSG00000136997 ENSG00000099942 PMC8395751__F10 Expression Profile of Genes Encoding Proteins Involved in Regulation of Vasculature Development and Heart Muscle Morphogenesis—A Transcriptomic Approach Based on a Porcine Model ENSG00000262634 ENSG00000113196 ENSG00000080345 ENSG00000134982 ENSG00000148798 ENSG00000173599 ENSG00000164949 PMC9423733__F1 Multifaceted Role of Autophagy in Endometrium Homeostasis and Disease ENSG00000177169 ENSG00000152348 ENSG00000110497 ENSG00000123395 ENSG00000083290 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC5360635__F1 Autophagy mechanism ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC4637888__F4 Novel function of the human oncogene Stil: Regulation of PC12 cell toxic susceptibility through the Shh pathway ENSG00000179091 ENSG00000164690 ENSG00000128602 PMC1934395__F2 Combined Effects of Thrombosis Pathway Gene Variants Predict Cardiovascular Events ENSG00000042832 ENSG00000134982 ENSG00000198734 ENSG00000178726 ENSG00000132693 PMC11645450__F3 Regulatory roles of the DUB family in signaling pathways ENSG00000135655 ENSG00000134982 ENSG00000102871 ENSG00000036672 ENSG00000198793 ENSG00000172046 ENSG00000168036 ENSG00000292211 ENSG00000111321 ENSG00000150455 ENSG00000310560 ENSG00000124356 ENSG00000052723 ENSG00000170832 ENSG00000180667 ENSG00000291527 ENSG00000102226 ENSG00000165312 ENSG00000162607 ENSG00000163681 ENSG00000143258 ENSG00000113645 ENSG00000137834 ENSG00000124422 ENSG00000264522 ENSG00000173039 ENSG00000150457 ENSG00000154124 ENSG00000127191 ENSG00000131023 ENSG00000151718 ENSG00000101557 ENSG00000047644 ENSG00000172936 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000066427 ENSG00000134588 ENSG00000277276 PMC7760721__F2 AB peptides are derived from the processing of the BAPP (APP) through the amyloidogenic pathway ENSG00000185933 ENSG00000128272 ENSG00000100219 ENSG00000074410 PMC7816272__F3 Dysregulation of NCC and TRPM6 common regulatory pathways ENSG00000092439 ENSG00000143867 ENSG00000080166 ENSG00000119121 PMC7057764__F1 Impact of lactic acid on tumor angiogenesis ENSG00000118520 ENSG00000100985 PMC6610018__F3 Interplay between the cGAS-cGAMP-STING pathway with mTORC1 signaling ENSG00000183735 PMC6610018__F2 Activation of the cGAS-cGAMP-STING pathway mediates obesity-induced inflammation and metabolic disorders ENSG00000183735 ENSG00000164430 PMC4048856__F2 HEPCIDIN AND IRON HOMEOSTASIS ENSG00000010704 ENSG00000106327 PMC2645306__F2 Migration of Airway Smooth Muscle Cells ENSG00000070831 ENSG00000291971 PMC11453023__F7 TLR-activating and the induced signaling pathway ENSG00000150455 ENSG00000127191 ENSG00000276561 ENSG00000239732 ENSG00000187554 ENSG00000134070 ENSG00000157625 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC10488294__F3 AML cell differentiation by S100A9 ENSG00000143546 ENSG00000163220 ENSG00000136869 PMC5766549__F6 Milk protein synthesis in bovine mammary gland ENSG00000145321 PMC12016237__F2 Mechanisms proposed for the AS-IV action in animal models of cardiovascular disorders ENSG00000278718 ENSG00000162711 ENSG00000026103 PMC5766549__F4 Activators and repressors of the regulatory network of genes associated with the bovine milk K-casein content ENSG00000064309 ENSG00000152463 ENSG00000090402 ENSG00000122966 ENSG00000186472 ENSG00000088926 ENSG00000291368 PMC6319272__F2 Schematic depicting the proposed hypothesis that resistance exercise-induced adaptations may require the Hippo pathway effectors YAP and TAZ ENSG00000104814 ENSG00000011566 ENSG00000114978 ENSG00000168067 ENSG00000150457 ENSG00000131023 PMC4803054__F7 Models depicting the multifaceted role of Mte1 in RF repair and CO promotion ENSG00000198887 ENSG00000178966 PMC11651441__F11 Inflammatory signaling pathways of SYGCT therapy for asthma-IBS ENSG00000148346 ENSG00000081041 ENSG00000134982 ENSG00000102871 ENSG00000173156 ENSG00000163220 ENSG00000168040 ENSG00000155313 ENSG00000049768 ENSG00000105639 ENSG00000143556 ENSG00000076604 ENSG00000106546 ENSG00000069667 ENSG00000169245 ENSG00000183735 ENSG00000108691 ENSG00000213658 ENSG00000137265 ENSG00000107485 ENSG00000157625 ENSG00000100985 ENSG00000056736 ENSG00000175104 PMC9200548__F3 Novel Therapeutic Strategies for Ischemic Stroke: Recent Insights into Autophagy ENSG00000177169 ENSG00000198793 PMC2761108__F8 Roles of BMP signaling pathways during SNS development ENSG00000123454 ENSG00000164107 ENSG00000107485 ENSG00000109132 ENSG00000139352 PMC9200548__F1 Novel Therapeutic Strategies for Ischemic Stroke: Recent Insights into Autophagy ENSG00000198793 ENSG00000171791 PMC6682745__F1 WNT/Beta-catenin signaling and the potential role of heterotrimeric G proteins ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC7834777__F8 Predicted mechanism after administering TCN in the liver ENSG00000175567 PMC10149931__F9 Wiskott-Aldrich syndrome protein interacts and inhibits diacylglycerol kinase alpha promoting IL-2 induction ENSG00000065357 ENSG00000070831 ENSG00000010810 PMC3836831__F2 Model of PfEMP1 head structure divergence ENSG00000135218 ENSG00000134982 ENSG00000173599 PMC4704136__F2 Cellular and molecular interactions between CLL cells and the tissue microenvironment ENSG00000178860 ENSG00000107562 ENSG00000111537 ENSG00000186716 ENSG00000113520 ENSG00000162692 ENSG00000277943 ENSG00000121966 PMC4532781__F1 PolyQ-HTT impairs autophagy ENSG00000173805 ENSG00000198793 ENSG00000197386 ENSG00000067900 PMC12125588__F3 Ginsenoside Rg1 in modulating myocardial hypertrophy and fibrosis ENSG00000087245 ENSG00000158828 ENSG00000173039 ENSG00000100985 ENSG00000036828 ENSG00000096717 PMC12125588__F2 Ginsenoside Rg1 in protecting ischemic myocardium ENSG00000162711 ENSG00000198793 ENSG00000158828 ENSG00000136869 PMC6823243__F3 SHP-2 in cytokine receptor signaling ENSG00000124102 ENSG00000198793 PMC6823243__F2 SHP-2-mediated activation of ERK ENSG00000291971 ENSG00000076641 PMC10380887__F1 MTOR Signaling: Emerging Role of Cyclic Nucleotide-Dependent Protein Kinases and Implications for Cardiometabolic Disease ENSG00000160584 ENSG00000106070 ENSG00000155792 ENSG00000145321 PMC6514310__F2 Upstream and downstream of mTORC1 and mTORC2 ENSG00000100150 ENSG00000177169 ENSG00000114388 ENSG00000065911 ENSG00000177058 ENSG00000198198 ENSG00000145979 ENSG00000085415 ENSG00000127580 ENSG00000164654 ENSG00000084774 PMC6514310__F1 mTORC1 and mTORC2 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC7432101__F1 Cartoon representation of DGK signaling in cancer ENSG00000291971 ENSG00000198793 ENSG00000163914 ENSG00000136997 PMC6274804__F1 Schema illustrating the regulation of the autophagic pathway under diverse stressful conditions in cancer cells ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC3637678__F1 MicroRNAs regulating myogenesis via PI3K/Akt signaling PMC2839263__F2 Emerging models for the role of Beta-arrestin in wingless (from Drosophila) and the oncogene int-1 (WNT) signalling ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000070831 ENSG00000168036 PMC7859115__F3 Cellular and molecular features of autophagy ENSG00000177169 ENSG00000123395 ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC3146004__F4 Pathway assignment of the important genes based on KEGG ENSG00000145604 ENSG00000111537 ENSG00000101146 ENSG00000132646 ENSG00000113558 ENSG00000172005 ENSG00000156574 ENSG00000123374 ENSG00000185591 ENSG00000276876 PMC7857022__F1 Class I PI3K signaling pathway simplified ENSG00000186716 PMC5615147__F2 Regulations of Nrf2 by several factors ENSG00000181788 ENSG00000177606 ENSG00000106546 ENSG00000079999 PMC4775111__F10 Scheme and coexpression network for a putative flavonol synthesis pathway in tobacco flowers PMC6928039__F7 CR3 triggers the Syk/calcineurin/NFATc pathway upon engagement by PGL-I-producing mycobacteria to rewire the innate response ENSG00000187796 ENSG00000172936 PMC11877449__F3 Interactions in the Tumor Microenvironment (TME) Affecting Lung Cancer Progression ENSG00000112715 PMC12220482__F2 Mechanism of NUSAP1 in cancer ENSG00000137804 ENSG00000134982 PMC10252036__F2 Various mechanisms that have been reported to regulate epithelial–mesenchymal transition (EMT) in SACC patients ENSG00000019991 ENSG00000147862 ENSG00000134982 ENSG00000138798 ENSG00000170558 ENSG00000198793 ENSG00000168036 PMC5225500__F1 Glutaminolysis in cancer cells ENSG00000125166 ENSG00000198793 ENSG00000136997 ENSG00000166123 ENSG00000115419 PMC3632418__F1 mTOR as a potential treatment target for epilepsy ENSG00000266173 PMC4702617__F2 Deletion of the RIM15 gene on the metabolic profile of a laboratory strain during alcoholic fermentation ENSG00000090863 ENSG00000166851 ENSG00000167900 PMC11877449__F2 PI3K/AKT/mTOR Pathway ENSG00000177169 ENSG00000146648 ENSG00000140443 PMC2349095__F2 Triggering and amplification of the Wnt/Beta-catenin pathway in osteocytes in response to load ENSG00000162337 ENSG00000167941 PMC10535221__F7 HAs induced LoVo cell apoptosis and inhibited the phosphorylation of Akt ENSG00000002330 ENSG00000026103 PMC11930217__F1 Key signal transduction processes of TGFB and Notch signaling pathways in renal cells ENSG00000148400 ENSG00000114315 PMC12182320__F1 Expression profile analysis of key genes in the GSL biosynthesis pathway in B42OE, B42WT, and B42CR ENSG00000069482 ENSG00000102010 PMC7979572__F3 Stress, Nutrient and Growth factor signaling pathways that affect translation ENSG00000198793 ENSG00000284161 ENSG00000167658 PMC5002468__F1 Calcineurin/NFAT signaling pathway ENSG00000198838 ENSG00000196218 ENSG00000198626 ENSG00000140443 PMC3894150__F1 Central Role of the PPARG Gene Network in Coordinating Beef Cattle Intramuscular Adipogenesis in Response to Weaning Age and Nutrition ENSG00000131473 ENSG00000135218 ENSG00000288174 ENSG00000151365 ENSG00000186480 ENSG00000169710 ENSG00000169884 ENSG00000221869 ENSG00000099194 ENSG00000062282 ENSG00000132170 ENSG00000245848 ENSG00000170365 ENSG00000009950 ENSG00000172216 ENSG00000170522 ENSG00000165175 ENSG00000196498 ENSG00000285070 ENSG00000177666 ENSG00000124253 ENSG00000102935 PMC4938774__F7 Elevated integrin A6B4 expression is associated with venous invasion and decreased overall survival in non-small cell lung cancer ENSG00000137673 ENSG00000058085 ENSG00000130702 ENSG00000134308 ENSG00000175592 ENSG00000105647 ENSG00000176105 ENSG00000101680 ENSG00000242372 ENSG00000108839 ENSG00000137975 ENSG00000164078 ENSG00000010810 ENSG00000136997 ENSG00000151914 ENSG00000146648 PMC2533786__F9 PI 3-kinase/AKT-dependent pathways involved in IL-1 induction of IL-6 ENSG00000124102 ENSG00000172936 ENSG00000175104 PMC9564263__F1 Systematic Interrogation of the Temperature Perturbation in the Insulin Signaling Pathway for Optogenetic Stimulation ENSG00000171105 ENSG00000169047 PMC3614492__F1 Calciomics: integrative studies of Ca2+-binding proteins and their interactomes in biological systems ENSG00000130643 ENSG00000167323 ENSG00000156026 ENSG00000036828 PMC8432036__F2 Canonical TGFB Signaling and Its Contribution to Endometrial Cancer Development and Progression—Underestimated Target of Anticancer Strategies PMC8829728__F3 Lipopolysaccharide-Induced Cell Signalling in Chronic Inflammation ENSG00000278718 ENSG00000162711 ENSG00000125538 ENSG00000189403 ENSG00000136869 PMC4973073__F4 Downregulation of PPAR pathway and bile acid biosynthesis and secretion pathway ENSG00000057252 ENSG00000151726 ENSG00000135218 ENSG00000167910 ENSG00000103375 ENSG00000099377 ENSG00000132170 ENSG00000157184 ENSG00000073060 ENSG00000134824 ENSG00000149809 ENSG00000036530 ENSG00000100979 ENSG00000197142 ENSG00000073734 ENSG00000158874 ENSG00000083807 ENSG00000113790 ENSG00000135929 PMC8829728__F4 Lipopolysaccharide-Induced Cell Signalling in Chronic Inflammation ENSG00000170458 ENSG00000136869 PMC9339684__F3 Immunosenescence: A Critical Factor Associated With Organ Injury After Sepsis ENSG00000164430 ENSG00000285109 ENSG00000115415 ENSG00000198793 ENSG00000168610 PMC5954621__F5 Bile acid regulation of bile acid synthesis ENSG00000160867 ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC3243049__F3 The autophagy pathway is affected at different steps in the various types of dementias ENSG00000198793 ENSG00000165280 PMC5928575__F2 Ovulatory cascade ENSG00000170961 ENSG00000109321 ENSG00000124882 ENSG00000123610 PMC3893993__F3 RAS-mitogen-activated protein kinase signaling pathway ENSG00000033327 ENSG00000166068 ENSG00000108061 PMC5954621__F2 Bile acid synthesis pathways ENSG00000167910 ENSG00000036530 ENSG00000180432 ENSG00000099377 ENSG00000203857 ENSG00000135929 PMC10525517__F2 RUNX1-Regulated Signaling Pathways in Ovarian Cancer ENSG00000138798 ENSG00000146648 PMC3888822__F2 Novel anti-HIV therapeutics targeting chemokine receptors and actin regulatory pathways ENSG00000070831 PMC6791355__F2 Cdc37 controls a network of intracellular protein kinases ENSG00000177169 ENSG00000105401 PMC5928575__F5 PGE2 mediates early implantation ENSG00000107562 ENSG00000146648 ENSG00000121966 PMC4702820__F4 Gene–gene network category and pharmacological category ENSG00000115425 ENSG00000175198 ENSG00000151365 ENSG00000133317 ENSG00000163082 PMC3947766__F1 Deciphering the function of nucleic acid sensing TLRs one regulatory step at a time ENSG00000239732 ENSG00000110057 PMC6370010__F3 Tale of the Good and the Bad Cdk5: Remodeling of the Actin Cytoskeleton in the Brain ENSG00000106683 ENSG00000149269 PMC3431702__F7 TLR signaling and proposed model for DMF-mediated impairment of DC maturation ENSG00000174125 ENSG00000183735 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC8446275__F1 Tissue Specific DNA Repair Outcomes Shape the Landscape of Genome Editing ENSG00000012048 ENSG00000051180 PMC5036051__F3 Integrating Multi-omics Data to Dissect Mechanisms of DNA repair Dysregulation in Breast Cancer ENSG00000156374 ENSG00000078900 ENSG00000154920 ENSG00000101057 ENSG00000187741 ENSG00000100479 ENSG00000197299 ENSG00000115816 ENSG00000213347 PMC6985875__F1 Mitochondrial function and localization in various lung epithelial cells during homeostasis ENSG00000168958 ENSG00000116688 ENSG00000158828 ENSG00000171109 ENSG00000057663 ENSG00000214253 PMC8037087__F2 Main mechanisms mediated by cannabinoids on angiogenesis, EMT, adhesion, invasion, and metastasis ENSG00000135446 ENSG00000177606 ENSG00000168036 ENSG00000121966 PMC5653149__F1 Regulation of Cellular Redox Signaling by Matricellular Proteins in Vascular Biology, Immunology, and Cancer ENSG00000138798 ENSG00000113140 PMC5653149__F4 Regulation of Cellular Redox Signaling by Matricellular Proteins in Vascular Biology, Immunology, and Cancer ENSG00000135218 ENSG00000291971 PMC8446275__F2 Tissue Specific DNA Repair Outcomes Shape the Landscape of Genome Editing PMC11186432__F4 Different regulatory functions of F-box proteins in gastric cancer ENSG00000159069 ENSG00000118564 ENSG00000078668 ENSG00000170558 ENSG00000103264 ENSG00000116661 ENSG00000131023 ENSG00000138081 ENSG00000109670 PMC7693799__F7 Molecular enrichment networks of genes associated with diabesity and the cluster 3 network enrichment analysis ENSG00000171105 ENSG00000130164 ENSG00000165458 ENSG00000067606 ENSG00000163131 ENSG00000169047 ENSG00000273686 ENSG00000100985 ENSG00000146648 ENSG00000113525 ENSG00000160691 PMC5729506__F8 Schematic EGFR signaling pathway ENSG00000138798 ENSG00000198793 ENSG00000168036 PMC8071398__F2 Classic signaling pathways activated by GnRH ENSG00000109163 ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC3985726__F47 Canonical (yellow background) and non-canonical (red background) Wnt/Beta-catenin signaling pathways are related to mechanical elements and actions responsible for cell polarization, migration and tissue organization ENSG00000134982 ENSG00000140575 ENSG00000163914 PMC9243238__F2 Endoplasmic Reticulum Stress and Pathogenesis of Vascular Calcification ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC9243238__F3 Endoplasmic Reticulum Stress and Pathogenesis of Vascular Calcification ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8432036__F5 Canonical TGFB Signaling and Its Contribution to Endometrial Cancer Development and Progression—Underestimated Target of Anticancer Strategies PMC9398856__F5 Therapeutic Effect of Melatonin in Premature Ovarian Insufficiency: Hippo Pathway Is Involved ENSG00000169047 ENSG00000198793 ENSG00000133124 ENSG00000089225 PMC7693799__F5 Molecular enrichment networks of genes associated with diabesity and the cluster 1 network enrichment analysis ENSG00000121552 ENSG00000041982 ENSG00000196839 ENSG00000163631 PMC8432036__F6 Canonical TGFB Signaling and Its Contribution to Endometrial Cancer Development and Progression—Underestimated Target of Anticancer Strategies PMC3887408__F1 Interactions of the Ras/PI3K/PTEN/Akt/mTOR and Ras/Raf/MEK/ERK pathways with GSK-3 ENSG00000177169 ENSG00000198793 ENSG00000169047 ENSG00000155792 ENSG00000196712 PMC9656973__F7 Visfatin-Induced Inhibition of miR-1264 Facilitates PDGF-C Synthesis in Chondrosarcoma Cells and Enhances Endothelial Progenitor Cell Angiogenesis ENSG00000145431 ENSG00000198793 PMC4646468__F4 Comprehensive MicroRNA Expression Profile Related to Hypoxia Adaptation in the Tibetan Pig ENSG00000132906 ENSG00000162889 ENSG00000002330 ENSG00000070831 ENSG00000291971 PMC5379981__F6 Model whereby both uracil glycosylases and the Pms2/Mlh1 complex enable A-T base pair mutagenesis with a distinct strand bias ENSG00000123415 ENSG00000130997 ENSG00000139372 ENSG00000095002 ENSG00000122512 PMC8674203__F2 TC2N: A Novel Vital Oncogene or Tumor Suppressor Gene In Cancers ENSG00000276776 ENSG00000002330 ENSG00000136997 PMC7348176__F7 Anticancer mechanism of HF for HCC ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC6927459__F5 Multifaceted activities of CD44v6 in PaCIC ENSG00000019991 ENSG00000087245 ENSG00000281324 ENSG00000002330 ENSG00000162337 ENSG00000105401 ENSG00000168036 ENSG00000121966 ENSG00000159216 ENSG00000157227 ENSG00000026508 ENSG00000100985 ENSG00000179348 PMC7016856__F2 Anti- and pro-fibrotic roles of Epac1 in cardiac fibroblasts ENSG00000105329 PMC2649265__F8 Insulin-PI3K-Akt signaling in AD ENSG00000100473 ENSG00000005882 ENSG00000169047 ENSG00000198793 ENSG00000164327 PMC6927459__F7 EpCAM, claudin7 and their cooperation in PaCa ENSG00000111537 ENSG00000281324 ENSG00000119888 ENSG00000134982 ENSG00000155011 ENSG00000177606 ENSG00000168036 ENSG00000127324 ENSG00000184304 PMC7016856__F3 Fibrotic signaling pathways by PKA and AKAPs ENSG00000047936 PMC6927459__F6 CXCR4 and PaCIC survival and motility ENSG00000070831 ENSG00000163914 ENSG00000168036 ENSG00000127324 ENSG00000164690 ENSG00000171791 ENSG00000128602 ENSG00000121966 PMC8127420__F4 Epidemiological link between obesity, type 2 diabetes mellitus and cancer ENSG00000138795 ENSG00000162337 ENSG00000168036 ENSG00000096717 PMC6865805__F2 Chronic infection of H ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC6627106__F4 Four branches of MOB control ENSG00000143093 ENSG00000128578 ENSG00000150457 ENSG00000131023 ENSG00000291442 PMC6624780__F9 TSL suppresses angiogenesis by inhibiting the VEGFR2 signaling pathway ENSG00000087245 ENSG00000135446 ENSG00000100985 PMC3084294__F4 The Complete Genome Sequence of ‘Candidatus Liberibacter solanacearum’, the Bacterium Associated with Potato Zebra Chip Disease ENSG00000122966 ENSG00000172005 ENSG00000062485 PMC6539837__F1 Some common metabolic features of adult stem cells are essential for the maintenance of their quiescence, number, proliferation potential, and differentiation ability ENSG00000143158 ENSG00000285121 ENSG00000005882 ENSG00000175567 ENSG00000143995 PMC6539837__F4 Intensity of information flow through the mTORC1-signaling pathway defines the fate of quiescent adult stem cells ENSG00000100811 ENSG00000019991 PMC8292097__F10 Carbon Monoxide-Releasing Molecule-2 Ameliorates Particulate Matter-Induced Aorta Inflammation via Toll-Like Receptor/NADPH Oxidase/ROS/NFKB/IL-6 Inhibition ENSG00000136869 ENSG00000162692 PMC11568095__F10 Network pharmacology and in vitro experiments to investigate the anti-gastric cancer effects of paeoniflorin through the RAS/MAPK signaling pathway ENSG00000087245 ENSG00000115904 ENSG00000100985 PMC3585940__F5 Gene Expression Profile Analysis of Type 2 Diabetic Mouse Liver ENSG00000157184 ENSG00000262785 ENSG00000135218 ENSG00000170522 ENSG00000100504 ENSG00000124253 ENSG00000113790 ENSG00000026103 PMC6428080__F1 Translational control mechanisms ENSG00000128272 ENSG00000144895 ENSG00000124882 ENSG00000198793 ENSG00000169047 ENSG00000146648 ENSG00000140443 PMC2914056__F6 Pathway packaging of the 'biopolymer metabolic process' module ENSG00000136492 ENSG00000104320 ENSG00000177606 ENSG00000132383 ENSG00000187741 ENSG00000173846 ENSG00000095002 ENSG00000067369 PMC3488095__F8 A model for SAHA mediated effects on A1AT folding and trafficking ENSG00000116406 ENSG00000127022 ENSG00000135506 PMC6680978__F4 The (a) glycolysis and (b) PKA-AMPK pathway genes and metabolites modulated by dietary BRBs during oral carcinogenesis ENSG00000005339 ENSG00000065989 ENSG00000170027 ENSG00000066044 ENSG00000164708 ENSG00000159399 PMC6052044__F1 Metabolic pathway reconstruction for Spirochaetes in hydrocarbon- and organohalide-contaminated environments ENSG00000180210 ENSG00000117525 ENSG00000198734 PMC4970823__F2 Regulation of cancer cell functions by hyaluronan (HA)‐receptor interactions ENSG00000142627 ENSG00000163914 ENSG00000026508 ENSG00000132849 PMC8395015__F1 Altered L-Arginine Metabolic Pathways in Gastric Cancer: Potential Therapeutic Targets and Biomarkers ENSG00000081181 ENSG00000118520 ENSG00000007171 PMC3887408__F5 Novel approaches of targeting signaling pathways in leukemia ENSG00000169136 ENSG00000198793 ENSG00000168036 ENSG00000096717 ENSG00000168610 PMC3283951__F5 The acetate/mevalonate pathway for the formation of IPP, the basic five-carbon unit of terpenoid biosynthesis ENSG00000197429 ENSG00000004961 ENSG00000062485 PMC6834135__F1 NK cell features in chronic HBV infection ENSG00000111537 ENSG00000139187 ENSG00000026508 PMC8570953__F1 Swertia chirayita suppresses the growth of non-small cell lung cancer A549 cells and concomitantly induces apoptosis via downregulation of JAK1/STAT3 pathway ENSG00000168040 ENSG00000026103 PMC5331729__F2 LncRNAs network in malignant transformation of HCC stem cells ENSG00000145604 ENSG00000150782 ENSG00000101751 ENSG00000132646 ENSG00000164362 ENSG00000123374 ENSG00000181555 ENSG00000118971 ENSG00000166169 ENSG00000102974 PMC5331729__F4 Roles of LncRNAs in the malignant transformation of breast CSCs ENSG00000128710 ENSG00000143379 ENSG00000168610 PMC8715196__F13 KDM6A Regulates Cell Plasticity and Pancreatic Cancer Progression by Noncanonical Activin Pathway PMC5988573__F1 Schematic diagram showing the positive feedback loop between Hippo-YAP/TAZ and IRS2-AKT signaling in the DKO livers ENSG00000134982 PMC4008004__F1 Hyperglycemia alters the expression of multiple genes of the transforming growth factor‐B (TGF‐B) pathway through the polyol pathway in retinal vessels ENSG00000057252 ENSG00000107779 ENSG00000111145 ENSG00000159128 ENSG00000037965 ENSG00000148400 ENSG00000026508 ENSG00000265972 PMC7867545__F10 The Impact of the CMT2B-causing RAB7 mutant protein on the endocytic pathway ENSG00000005893 ENSG00000074319 PMC12153797__F2 Core signaling networks that contribute to the development of vasculogenic mimicry ENSG00000149311 ENSG00000123374 PMC12153797__F1 Exploration of the VE-cadherin structure and the transformations it undergoes when it comes into contact with VEGF-A ENSG00000291971 PMC6547810__F8 Schematic drawing of the suggested intracellular signaling pathways of LIF and OSM receptors in osteoblasts mediating expression of osteoclastogenic factors, osteoclast formation and bone resorption ENSG00000145623 ENSG00000099985 ENSG00000128342 ENSG00000168610 ENSG00000160691 PMC12153797__F4 Pathways in immune cells that short-chain fatty acids generated by GM triggers ENSG00000124216 ENSG00000124766 ENSG00000272398 ENSG00000026508 PMC12153797__F3 Correlations of microbiome and different cancers ENSG00000026508 ENSG00000136869 ENSG00000168610 PMC8019825__F8 Summary of the pathological alterations of CRS-3 ENSG00000129946 ENSG00000198793 PMC7108978__F2 Simultaneous utilization of 2H and 13C tracers provides insights into distinct pathways of hepatic metabolism ENSG00000122966 ENSG00000172005 ENSG00000166278 PMC10740933__F3 (Left) Initial biosynthetic pathway for the formation of a lipofuscin fluorophore A2E in photoreceptor outer segment (OS) and its structure as a component of lipofuscin (LF) in the RPE cell ENSG00000175054 ENSG00000197713 PMC9616778__F8 Cilostazol Alleviates NLRP3 Inflammasome–Induced Allodynia/Hyperalgesia in Murine Cerebral Cortex Following Transient Ischemia: Focus on TRPA1/Glutamate and Akt/Dopamine/BDNF/Nrf2 Trajectories ENSG00000162711 ENSG00000104321 ENSG00000131095 ENSG00000096717 PMC9304404__F7 Mechanistic diagram of apatinib in NSCLC cells ENSG00000128272 ENSG00000070669 PMC3096649__F7 IGF1R Signaling in Ewing Sarcoma Is Shaped by Clathrin-/Caveolin-Dependent Endocytosis ENSG00000169291 ENSG00000169047 ENSG00000140443 PMC2805793__F1 Ligand binding and subsequent Erbb dimer formation initiates signaling through a complex array of intracellular pathways that initiate and control a range of cellular processes ENSG00000002330 ENSG00000065361 ENSG00000198793 PMC7645337__F7 Core molecular net words identified by IPA ENSG00000064601 ENSG00000177606 ENSG00000159399 PMC4386979__F2 Intracellular signal paths coupled to the opioid receptors and implicated in cardiac stress signalling and cardioprotection ENSG00000138798 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC10568034__F2 Manner in which the studied product acts on the Wnt pathway in lung cancer ENSG00000134982 ENSG00000168036 PMC3320915__F7 Model of proposed CCR7/CCL19 signaling pathway in T cells ENSG00000127528 ENSG00000126353 PMC9690286__F1 Small Non-Coding RNAs in Human Cancer ENSG00000113360 ENSG00000132341 PMC7690430__F3 Targeting the PI3K–AKT–mTOR pathway to treat prostate cancer PMC4448502__F4 Pathway analysis showed a strong role for early response genes and sterol regulatory elements ENSG00000131473 ENSG00000128016 ENSG00000110799 ENSG00000130522 ENSG00000122877 ENSG00000175567 ENSG00000079435 ENSG00000159335 ENSG00000198355 ENSG00000198911 ENSG00000292033 PMC5573409__F4 Diagram of P53 signaling pathway with overlaid molecular activity prediction after heat stress ENSG00000140464 PMC4021040__F2 Targeting glioma stem cells: a novel framework for brain tumors ENSG00000138798 ENSG00000146648 PMC8945343__F5 Reactive Oxygen Species Induced Pathways in Heart Failure Pathogenesis and Potential Therapeutic Strategies ENSG00000096088 ENSG00000214285 ENSG00000265972 PMC8197763__F8 Action mechanism of H2A.Z in HCC ENSG00000071564 ENSG00000166145 ENSG00000058091 ENSG00000124762 PMC8945343__F4 Reactive Oxygen Species Induced Pathways in Heart Failure Pathogenesis and Potential Therapeutic Strategies ENSG00000116688 ENSG00000175567 ENSG00000171109 PMC6056717__F1 Coenzyme Q10 deficiencies: pathways in yeast and humans ENSG00000132423 ENSG00000267673 ENSG00000119723 ENSG00000161513 ENSG00000197429 ENSG00000171759 ENSG00000164597 ENSG00000137714 ENSG00000173085 ENSG00000167186 PMC12177077__F5 MBD2 in autoimmune diseases ENSG00000068079 ENSG00000071655 ENSG00000115415 ENSG00000134046 PMC5436564__F6 Working model of E2-activated SGK1 involvement in negative regulation of TLR-4-mediated apoptosis and pro-inflammatory TH1 immune responses at the feto-maternal interface ENSG00000150907 ENSG00000137265 ENSG00000118515 ENSG00000136869 ENSG00000171791 PMC6721316__F1 Protein functional interactome network for differentially expressed proteins identified in Pancreatic ductal adenocarcinoma (PDAC) tissue; down-regulated proteins (A) and up-regulated proteins (B) ENSG00000168028 ENSG00000162438 ENSG00000241553 ENSG00000197746 ENSG00000148175 ENSG00000178209 ENSG00000089157 ENSG00000049860 ENSG00000188783 PMC6779857__F1 The core components of the Hippo signaling pathway ENSG00000150457 ENSG00000131023 PMC4956504__F1 Androgen pathway and genes involved in androgen biosynthesis and metabolism ENSG00000086696 ENSG00000203857 PMC4907806__F3 Exercise-Driven Metabolic Pathways in Healthy Cartilage ENSG00000002330 ENSG00000111837 ENSG00000135605 PMC9040077__F1 Cytolytic CD4+ and CD8+ Regulatory T-Cells and Implications for Developing Immunotherapies to Combat Graft-Versus-Host Disease ENSG00000111537 ENSG00000102871 ENSG00000168040 ENSG00000026103 PMC8451139__F8 New Mfn-2 related synthetic peptide promotes vascular smooth muscle cell apoptosis via regulating the mitochondrial apoptotic pathway by inhibiting Akt signaling ENSG00000002330 ENSG00000116688 ENSG00000168040 ENSG00000026103 PMC6776190__F9 Kyoto Encyclopedia of Genes and Genomes pathway analysis in SK-BR-3 vs ENSG00000170365 ENSG00000137834 ENSG00000100387 ENSG00000198742 ENSG00000113558 ENSG00000185591 ENSG00000205250 ENSG00000137801 PMC11354542__F6 Neurotrophin-signaling pathways in the high-intensity exercise group (blue: downregulation) ENSG00000169291 PMC6776190__F7 Kyoto Encyclopedia of Genes and Genomes pathway analysis in SK-BR-3 vs ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11783322__F6 Protein-protein interaction (PPI) analysis (A) PPI network analyzed through STRING web site (www ENSG00000015285 PMC9204593__F2 Transient Receptor Potential Channels, Natriuretic Peptides, and Angiotensin Receptor-Neprilysin Inhibitors in Patients With Heart Failure ENSG00000173786 ENSG00000096088 PMC6357062__F1 Intracellular negative immune regulators of dendritic cells (DCs) ENSG00000173039 ENSG00000168610 PMC5564223__F1 The influence of Notch and Wnt pathways in the oncogenesis and stemness maintenance of breast cancer cells in the absence of estrogen ENSG00000133961 PMC4957033__F5 Top network of THC-regulated miRNAs ENSG00000012048 ENSG00000120833 ENSG00000135446 ENSG00000137265 ENSG00000136826 ENSG00000138385 PMC11173095__F3 VEGF signaling pathway ENSG00000107338 ENSG00000291971 ENSG00000198793 ENSG00000111816 PMC4762491__F2 Man-P-Dol acts as mannosyl donor for the synthesis of M9-DLO, GPI anchors, and C- and O-mannosylated proteins ENSG00000000419 ENSG00000214160 ENSG00000136908 ENSG00000128039 PMC4795779__F1 Involvement of Endoplasmic Reticulum Stress in TULP1 Induced Retinal Degeneration ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC2958833__F2 Nutritional Programming in the Rat Is Linked to Long-Lasting Changes in Nutrient Sensing and Energy Homeostasis in the Hypothalamus ENSG00000164327 ENSG00000069667 PMC8919014__F3 Inflammatory bowel disease-related colorectal cancer: Past, present and future perspectives ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000168610 PMC5337497__F3 Schematic presentation of the tricarboxylic acid cycle (TCA) pathway and amino acid biosynthesis, as affected by the chlorotic mutation ENSG00000131473 ENSG00000122966 ENSG00000091140 ENSG00000062485 PMC6397842__F2 Schematic overview of bone cells and extracellular matrix components involved in regulating bone homeostasis ENSG00000167941 ENSG00000113140 PMC3894810__F5 New insights into host–pathogen interactions during Entamoeba histolytica liver infection PMC6366073__F5 Euglena gracilis has flexible and fault-tolerant mitochondrial metabolism ENSG00000182511 ENSG00000166278 ENSG00000081051 ENSG00000136003 PMC2671802__F1 ALPS and CEDS illustrate signaling pathways for lymphocyte apoptosis and activation ENSG00000168040 ENSG00000026103 PMC6046065__F1 Pharmacological modulation of mitochondrial calcium homeostasis ENSG00000005059 ENSG00000107745 ENSG00000156026 ENSG00000091140 PMC5247608__F7 Model depicting roles of Sufu in chaperoning Gli functions during Shh signaling ENSG00000106571 ENSG00000166813 ENSG00000150459 ENSG00000164690 ENSG00000128602 ENSG00000169375 PMC8034539__F1 B3-adrenergic signaling pathway that promotes thermogenesis in adipocytes ENSG00000137265 ENSG00000106459 PMC9251357__F2 Gasdermins in Innate Host Defense Against Entamoeba histolytica and Other Protozoan Parasites ENSG00000278718 ENSG00000131669 ENSG00000162711 ENSG00000125538 PMC8034539__F2 Schematic models of BMP7 and TGFB signaling pathways in thermogenesis ENSG00000170365 PMC3950821__F3 Leveraging melanocortin pathways to treat glomerular diseases ENSG00000070831 ENSG00000291971 ENSG00000125538 ENSG00000163914 PMC3091524__F3 Role of ATR- or ATM-dependent modulation of WRN function in promoting correct recovery from replication arrest ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000165392 ENSG00000051180 PMC2169053__F6 Model for SCF-mediated regulation of hFBH1 and Srs2 turnover in response to DNA damage ENSG00000132646 ENSG00000113558 ENSG00000070950 PMC9277879__F2 Gut–liver axis in sepsis: interaction mechanisms and therapeutic potential ENSG00000172936 ENSG00000136869 PMC3372318__F3 The two major signaling cascades operating in cancer, following overactivation of the INSR/IGF-IR signaling pathways ENSG00000171105 ENSG00000198793 PMC9110832__F1 Involvement of Caspases in Neuroinflammation and Neuronal Apoptosis in Chronic Pain and Potential Therapeutic Targets ENSG00000186810 ENSG00000137077 ENSG00000125538 ENSG00000196689 PMC6558407__F5 Insulin and autophagy signaling modulation in Huntington’s disease (HD) ENSG00000169047 ENSG00000145782 ENSG00000057663 PMC7144527__F8 Schematic model for RNF125 and Cbl-b in LPS-induced endotoxemia ENSG00000278718 ENSG00000162711 ENSG00000137757 ENSG00000125538 ENSG00000196954 ENSG00000172936 ENSG00000136869 ENSG00000101695 PMC3638063__F1 MTOR signaling pathway ENSG00000106070 ENSG00000198793 ENSG00000118515 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC7046304__F8 SPAG5‐AS1/miR‐769‐5p/YY1‐positive feedback loop transcriptionally induced SPAG5 and SPAG5‐AS1 interacted with USP14 to induce de‐ubiquitination of SPAG5, so that AKT/mTOR signalling was activated to inhibit autophagy and induce apoptosis in podocytes ENSG00000100811 ENSG00000198793 ENSG00000076382 ENSG00000101557 PMC4971466__F4 Dynamic mRNA and miRNA expression analysis in response to intermuscular bone development of blunt snout bream (Megalobrama amblycephala) ENSG00000170365 ENSG00000111537 ENSG00000198742 ENSG00000113558 PMC8460909__F7 Myeloid-Derived Suppressor Cells Alleviate Renal Fibrosis Progression via Regulation of CCL5-CCR5 Axis PMC7959294__F10 Schematic diagram illustrating the potential targets of HSR2104 to inhibit inflammatory responses and cell migration in BV2 cells ENSG00000172936 ENSG00000136869 PMC8964740__F2 Main mechanisms of miR-31 in oral squamous cell carcinoma (OSCC) ENSG00000116729 ENSG00000150457 ENSG00000133961 ENSG00000142082 ENSG00000146648 PMC8215340__F1 Metformin, Macrophage Dysfunction and Atherosclerosis ENSG00000162711 ENSG00000108691 ENSG00000135218 ENSG00000136869 ENSG00000126353 ENSG00000160179 ENSG00000107731 ENSG00000075239 ENSG00000144959 PMC6719526__F4 Metabolic reconstruction of the isolated strains Halonotius terrestris sp ENSG00000106078 PMC5766142__F6 Methylene-tetrahydrofolate reductase contributes to allergic airway disease ENSG00000005981 ENSG00000066923 ENSG00000106123 ENSG00000110048 ENSG00000106436 ENSG00000285152 ENSG00000183484 ENSG00000112038 ENSG00000038382 ENSG00000185386 ENSG00000185482 ENSG00000292373 ENSG00000166603 PMC6558407__F2 PI3K-AKT-mTOR signaling and Metformin targets ENSG00000169047 PMC9665039__F3 Signalling by TNFR1 and overview of the three characterized cell death checkpoints in the TNFR1 pathway ENSG00000278718 ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC7583940__F1 Canonical pathway of microRNA (miRNA) biogenesis ENSG00000092847 ENSG00000128191 ENSG00000113360 ENSG00000134698 ENSG00000123908 PMC8985609__F2 Activation of the non-canonical NLRP3 inflammasome ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC9735758__F3 IL-1RAP, a Key Therapeutic Target in Cancer ENSG00000140992 ENSG00000033327 ENSG00000137033 ENSG00000125538 ENSG00000136696 ENSG00000136694 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000184216 PMC7923182__F11 Scheme of reactions proposed for Rho pathway modelling ENSG00000100592 ENSG00000111186 PMC8466454__F7 Lycopene Protects Intestinal Epithelium from Deoxynivalenol-Induced Oxidative Damage via Regulating Keap1/Nrf2 Signaling ENSG00000178573 ENSG00000079999 PMC6944231__F5 Presynaptic proteins that were altered in AD ENSG00000186472 ENSG00000010810 ENSG00000220205 ENSG00000105402 ENSG00000137766 ENSG00000141367 PMC5360511__F5 PPARG targeted oral cancer treatment and additional utility of genomics analytic techniques ENSG00000151702 ENSG00000169704 ENSG00000135218 ENSG00000110514 ENSG00000272398 PMC6944231__F3 Pathway analyses of significantly altered proteins by IPA ENSG00000116044 ENSG00000177301 ENSG00000099940 ENSG00000132639 ENSG00000067715 ENSG00000079999 ENSG00000065135 ENSG00000163032 ENSG00000137100 ENSG00000006451 ENSG00000220205 ENSG00000152767 ENSG00000089199 ENSG00000117016 ENSG00000162188 PMC4148307__F8 Hypoxia Promotes Uveal Melanoma Invasion through Enhanced Notch and MAPK Activation ENSG00000198793 ENSG00000088256 PMC11106741__F2 Esc, a compound with potential anticancer properties, promotes apoptosis and inhibits the proliferation of tumor cells ENSG00000198793 ENSG00000168036 ENSG00000185591 ENSG00000168610 ENSG00000079999 PMC11106741__F1 Esc in cancer cells was revealed to be related to apoptosis, which is governed by the mitochondrial pathway, ER stress and ferritinophagy ENSG00000116044 ENSG00000167468 ENSG00000167996 ENSG00000185591 ENSG00000100219 ENSG00000167182 PMC3891875__F1 Wnt signaling ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC6471465__F6 Signaling pathway involved in intact or papain-hydrolyzed glycomacropeptide modulation on RAW 264.7 macrophage response to lipopolysaccharide or hydrogen peroxide ENSG00000172936 ENSG00000136869 ENSG00000079999 PMC7017369__F7 Signaling cascades of RA-mediated repression of B3GALT5-LTR promoter activity that reduce SSEA3 synthesis in human ES cells ENSG00000183778 ENSG00000096717 ENSG00000168610 PMC8415231__F2 Targeting the Wnt/Beta-Catenin Signaling Pathway as a Potential Therapeutic Strategy in Renal Tubulointerstitial Fibrosis ENSG00000156076 ENSG00000178573 ENSG00000134982 ENSG00000168036 ENSG00000104332 PMC2833197__F7 Transcriptional Regulation of VEGF-A by the Unfolded Protein Response Pathway ENSG00000128272 ENSG00000100219 ENSG00000112715 PMC2579774__F4 HIV-1 infected astrocytes and the microglial proteome ENSG00000074800 ENSG00000163848 ENSG00000196743 ENSG00000177600 PMC8124582__F2 Posttranslational Modification of Waxy to Genetically Improve Starch Quality in Rice Grain ENSG00000262788 ENSG00000169299 PMC548008__F7 The molecular mechanisms involved in the TGF-Beta-Smad7 signaling pathway resulting in activation of Akt and p38, followed by phosphorylation and inactivation of GSK-3B ENSG00000168036 PMC4684418__F1 Targeting Pink1-Parkin-Mediated Mitophagy for Treating Liver Injury ENSG00000135655 ENSG00000156735 ENSG00000215475 ENSG00000158828 ENSG00000135093 PMC7353140__F1 Features of the nuclear envelope and ER and regulation of and functions for lipid asymmetry at the inner nuclear membrane (INM) ENSG00000173599 ENSG00000175826 ENSG00000069248 PMC8524782__F2 Molecular Mechanisms of Hepatoblastoma ENSG00000019991 ENSG00000162337 ENSG00000134982 ENSG00000145826 ENSG00000168036 ENSG00000196208 PMC8240219__F9 Tanshinone I exerts cardiovascular protective effects in vivo and in vitro through inhibiting necroptosis via Akt/Nrf2 signaling pathway ENSG00000178573 ENSG00000168404 ENSG00000079999 PMC8348825__F1 Immunoendocrine Dysregulation during Gestational Diabetes Mellitus: The Central Role of the Placenta ENSG00000125538 ENSG00000169047 ENSG00000136111 ENSG00000140443 PMC2699361__F1 The ER–mitochondria apoptotic signalling pathway operating in cells devoid of mitochondrial BAK and BAX, and of ER-located BAX ENSG00000002330 ENSG00000127191 PMC8348825__F2 Immunoendocrine Dysregulation during Gestational Diabetes Mellitus: The Central Role of the Placenta ENSG00000042832 PMC4236175__F1 Examining the Polymorphisms in the Hypoxia Pathway Genes in Relation to Outcome in Colorectal Cancer ENSG00000107562 ENSG00000124440 PMC6801506__F3 The most significant Ingenuity Pathway Analysis (IPA) network of differentially regulated proteins in the MHO group compared to those from the MUHO group ENSG00000186395 ENSG00000132478 ENSG00000106927 PMC9279723__F1 Autophagy in Bone Remodeling: A Regulator of Oxidative Stress ENSG00000198793 ENSG00000112561 PMC3789264__F8 Brain site-specific proteome changes in aging-related dementia ENSG00000142192 ENSG00000150991 ENSG00000078369 ENSG00000184524 ENSG00000120885 PMC3049118__F3 Endocrine system development and function genes increase in the spleen of CVB3 infected males at 12 h pi ENSG00000004478 ENSG00000089685 ENSG00000140403 ENSG00000149554 ENSG00000038945 ENSG00000115317 PMC2902124__F1 TLR signalling ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000164342 PMC3789264__F7 Ingenuity Pathway Analysis (IPA)-generated network of isobaric tag for relative and absolute quantitation (iTRAQ)-identified proteins and their interacting partners in Alzheimer's disease (AD) cerebellum (Cb) ENSG00000159733 ENSG00000116521 ENSG00000118363 ENSG00000197971 ENSG00000168297 ENSG00000097021 ENSG00000152492 ENSG00000187714 PMC3789264__F6 Ingenuity Pathway Analysis (IPA)-generated network of isobaric tag for relative and absolute quantitation (iTRAQ)-identified proteins and their interacting partners in Alzheimer's disease (AD) parietal cortex (pCx) ENSG00000197043 ENSG00000198816 ENSG00000198157 ENSG00000291574 ENSG00000125459 ENSG00000123472 PMC3169997__F1 Epithelial cell cycle arrest in G2/M and epigenetic changes in fibroblasts coordinately promote kidney fibrosis ENSG00000196839 ENSG00000111344 PMC3789264__F5 Ingenuity Pathway Analysis (IPA)-generated network of isobaric tag for relative and absolute quantitation (iTRAQ)-identified proteins and their interacting partners in Alzheimer's disease (AD) hippocampus (Hp) ENSG00000184524 ENSG00000197971 ENSG00000148798 ENSG00000163631 PMC3277752__F2 Browsing the ApoptoProteomics database ENSG00000002330 ENSG00000168040 PMC9148284__F1 Cellular and Molecular Events Leading to Paraquat-Induced Apoptosis: Mechanistic Insights into Parkinson’s Disease Pathophysiology ENSG00000144895 ENSG00000115317 ENSG00000079999 PMC8509056__F6 Molecular and Metabolic Insights into Anthocyanin Biosynthesis for Leaf Color Change in Chokecherry (Padus virginiana) PMC8387351__F1 Stress response pathways dysregulated with age and injury: ENSG00000128272 PMC5177517__F6 Proposed model for the mechanism of SNRK regulation of ROCK activity ENSG00000163914 ENSG00000163788 PMC3049118__F6 Cardiovascular disease genes increase in the spleen of CVB3 infected males at 12 h pi ENSG00000261701 ENSG00000164879 ENSG00000107562 ENSG00000112208 ENSG00000061676 PMC2654353__F5 From nutrients to HIF and from HIF to metabolism ENSG00000198793 ENSG00000159399 PMC2654353__F7 From the extracellular matrix to HIF and from HIF to the extracellular matrix ENSG00000134013 ENSG00000198793 ENSG00000121966 PMC5007661__F3 Potential impact of bone tissue engineering in the clinic ENSG00000164828 ENSG00000002330 ENSG00000291971 ENSG00000134982 PMC3229969__F2 Roles of FGF signaling in stem cell self-renewal, senescence and aging PMC4490940__F10 Possible pathways of Cd-induced MAPK/ERK signaling ENSG00000033327 ENSG00000291971 ENSG00000113070 ENSG00000146648 PMC1991338__F1 ZIP1 expression and zinc accumulation in the pathway and bioenergetics of citrate production and citrate oxidation in normal versus malignant prostate cells ENSG00000122966 ENSG00000172005 ENSG00000062485 PMC7019052__F3 Skeletal muscle gene expression in Hereford and Holstein-Friesian vs Limousin visualized on the p38 MAPK signaling ENSG00000137275 ENSG00000115415 ENSG00000102871 ENSG00000291761 ENSG00000100784 ENSG00000127191 ENSG00000160691 PMC4628569__F3 IL-27-induced modulation of autoimmunity and its therapeutic potential ENSG00000105397 ENSG00000115415 ENSG00000122877 ENSG00000107485 ENSG00000049768 ENSG00000168610 ENSG00000106546 PMC4706927__F5 Putative inhibitory pathway of macrophage-mediated inflammatory signaling responses, as suppressed by KTH-13-AD1 ENSG00000291971 ENSG00000172936 ENSG00000136869 PMC7602422__F1 Aryl-hydrocarbon Receptor (AhR) Signaling Pathway in Osteoclasts ENSG00000140505 ENSG00000131196 ENSG00000106546 PMC7757040__F2 Diagrammatic illustration of the mechanism by H2S donors in regulating autophagy and cell migration ENSG00000100234 ENSG00000106683 ENSG00000170558 ENSG00000198793 ENSG00000168036 ENSG00000185591 ENSG00000057663 PMC6697704__F1 Main molecular interactions implemented in the model ENSG00000019991 PMC3987972__F3 Intracellular signalling pathways mediated by HLA class I or II antibody binding to endothelial cells ENSG00000124789 ENSG00000042832 ENSG00000184995 ENSG00000163914 ENSG00000215301 ENSG00000161960 PMC7019052__F4 Skeletal muscle gene expression in Hereford and Holstein-Friesian vs Limousin visualized on IL-1 signaling ENSG00000104365 ENSG00000282905 ENSG00000109320 ENSG00000095015 ENSG00000254445 ENSG00000065559 ENSG00000162924 ENSG00000105647 ENSG00000213341 ENSG00000130159 ENSG00000006062 ENSG00000179295 ENSG00000169967 ENSG00000244687 ENSG00000067606 ENSG00000177606 ENSG00000125538 ENSG00000157625 ENSG00000172936 ENSG00000124181 ENSG00000175104 PMC6965011__F2 Proposed model depicting regulation and role of METTL3 and FTO in BMSC adipogenesis and osteogenesis with regard to osteoporosis ENSG00000152266 ENSG00000135414 ENSG00000132170 PMC5335607__F3 Gene networks activated by specific patterns of action potentials in dorsal root ganglia neurons ENSG00000173599 ENSG00000026508 ENSG00000127948 PMC7278761__F3 Schematic presentation of interactions between nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and nuclear factor-kappa B (NFKB) transcription factors PMC7433199__F3 Signaling pathways other mucins involved in non-small cell lung cancer ENSG00000087245 ENSG00000291363 ENSG00000142611 ENSG00000132646 ENSG00000100985 ENSG00000124664 ENSG00000168610 ENSG00000146648 ENSG00000145113 ENSG00000293532 PMC6386916__F7 EtOAc extract of L ENSG00000080166 PMC6958341__F5 Overview of the metabolic pathway changes in murine 3T3-L1 adipocytes due to insulin or TNFA treatments ENSG00000156467 ENSG00000189043 ENSG00000110717 ENSG00000079435 ENSG00000125995 ENSG00000026103 PMC3357552__F7 TLR4 signaling in alcoholic steatohepatitis and fibrosis ENSG00000111537 ENSG00000105329 ENSG00000172936 ENSG00000136869 ENSG00000108821 ENSG00000277943 ENSG00000164342 PMC8851315__F1 Mitochondrial-Derived Peptides in Diabetes and Its Complications ENSG00000122756 ENSG00000168610 PMC11392669__F10 Tumoral VISTA facilitation of the proliferation of CML cells and suppression of apoptosis ENSG00000033327 ENSG00000002330 ENSG00000198793 ENSG00000171791 ENSG00000099942 PMC8195260__F2 Multiomics-Identified Intervention to Restore Ethanol-Induced Dysregulated Proteostasis and Secondary Sarcopenia in Alcoholic Liver Disease ENSG00000129219 ENSG00000163435 ENSG00000171105 ENSG00000002330 ENSG00000198793 ENSG00000163914 ENSG00000168610 ENSG00000089159 PMC4077663__F2 Leptin–brain melanocortin system interaction ENSG00000148798 ENSG00000115138 ENSG00000166603 PMC3164457__F5 Mi-2/NuRD complex depletion in germinal center B cells leads to alterations in chromatin, checkpoint activation, and delayed progression through S phase ENSG00000149311 ENSG00000134057 ENSG00000143379 ENSG00000123374 ENSG00000051180 ENSG00000111642 ENSG00000093009 PMC5727169__F5 Pathway analysis using WikiPathways revealed that the factors related to the calcium signalling pathway (Kelder, T., Chichester, C., Hanspers, K.: Calcium Regulation in the Cardiac Cell (Danio rerio) ENSG00000090104 ENSG00000170027 ENSG00000197471 ENSG00000117152 PMC3357552__F1 Overview of TLR signaling ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC2955995__F1 Targeting Notch signaling pathway to overcome drug-resistance for cancer therapy ENSG00000148400 ENSG00000074181 PMC5544253__F4 BET bromodomain inhibition suppresses innate inflammatory and profibrotic transcriptional networks in heart failure ENSG00000144648 ENSG00000105329 ENSG00000172216 ENSG00000162630 ENSG00000092621 ENSG00000177606 ENSG00000173039 ENSG00000189067 PMC6582499__F8 Schematic diagram illustrate the potential mechanisms of VPA and gemcitabine on pancreatic cancer cells ENSG00000168283 ENSG00000168610 ENSG00000164949 PMC10883245__F8 DOCK7 in EVs mediates intercellular communication between TAMs and CRC cells ENSG00000116641 ENSG00000150907 PMC6814379__F1 Glucose metabolism, energy production, and its importance in DNA replication and epigenetic homeostasis ENSG00000092621 ENSG00000145321 ENSG00000146733 PMC4806302__F6 Hedgehog associated to microparticles inhibits adipocyte differentiation via a non-canonical pathway ENSG00000164690 ENSG00000128602 ENSG00000281857 PMC11642109__F1 Schematic illustration showing the effects of the sympathetic nervous system (SNS) and the renin–angiotensin system (RAS) on cancer development ENSG00000102145 ENSG00000130234 ENSG00000198793 ENSG00000168610 PMC8391894__F2 DNA Polymerase θ: A Cancer Drug Target with Reverse Transcriptase Activity ENSG00000012048 ENSG00000138346 ENSG00000051180 ENSG00000177084 PMC5689469__F6 Proposed mechanism of muscle immaturity in CDM ENSG00000168610 ENSG00000102974 PMC2756021__F3 Neuroprotective Effects of the Complement Terminal Pathway During Demyelination: Implications for Oligodendrocyte Survival ENSG00000002330 ENSG00000026103 PMC5995803__F8 Multiscale networks identified within neurons contain neuron-specific modules ENSG00000182901 ENSG00000140992 ENSG00000094631 ENSG00000121989 ENSG00000160075 ENSG00000121940 ENSG00000089157 ENSG00000265491 ENSG00000120256 ENSG00000101132 ENSG00000130024 ENSG00000187957 ENSG00000072210 ENSG00000140455 ENSG00000116350 ENSG00000103365 ENSG00000164929 ENSG00000196914 ENSG00000146267 ENSG00000025800 ENSG00000196712 ENSG00000288591 ENSG00000149313 ENSG00000160460 ENSG00000053524 ENSG00000162642 ENSG00000144535 ENSG00000183354 ENSG00000108298 ENSG00000147533 ENSG00000082515 ENSG00000179292 ENSG00000103202 ENSG00000077157 ENSG00000182195 ENSG00000079156 ENSG00000106780 ENSG00000058600 ENSG00000175745 ENSG00000151229 ENSG00000170464 ENSG00000140319 ENSG00000000419 ENSG00000097033 ENSG00000131495 ENSG00000198793 ENSG00000135333 ENSG00000100461 ENSG00000132485 ENSG00000162402 ENSG00000124201 ENSG00000283391 ENSG00000171189 ENSG00000166448 ENSG00000150938 ENSG00000125814 ENSG00000291941 ENSG00000100906 ENSG00000144331 ENSG00000138411 ENSG00000274112 ENSG00000162368 ENSG00000151746 ENSG00000101972 ENSG00000108924 ENSG00000050165 ENSG00000055609 ENSG00000177981 ENSG00000162599 ENSG00000119314 ENSG00000122970 ENSG00000204217 ENSG00000134313 PMC7172983__F1 CGAS-STING pathway of cytosolic DNA sensing ENSG00000177169 ENSG00000183735 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000157954 ENSG00000198925 PMC8058381__F7 Fubaiju protected ARPE-19 cells oxidative damage by activating PI3K/Akt mediated Nrf2/HO-1 signaling pathway ENSG00000181019 PMC3524627__F8 Model depicting the regulation of DNA damage-induced germ cell apoptosis by C ENSG00000118515 PMC9448988__F2 Lung cancer in never smokers: Tumor immunology and challenges for immunotherapy ENSG00000111537 ENSG00000169429 ENSG00000146648 PMC8692584__F1 E3 Ubiquitin Ligases and Deubiquitinases in Inflammatory Bowel Disease: Friend or Foe? ENSG00000104856 ENSG00000132109 ENSG00000165188 ENSG00000167207 ENSG00000137275 ENSG00000173039 ENSG00000162924 ENSG00000111321 ENSG00000127191 ENSG00000106100 ENSG00000291527 ENSG00000136869 ENSG00000157625 ENSG00000172936 ENSG00000112186 ENSG00000083799 ENSG00000162722 ENSG00000130726 PMC10178682__F1 Simplified picture of cancer metabolism ENSG00000125166 ENSG00000103257 ENSG00000166123 ENSG00000115419 ENSG00000159399 ENSG00000062485 PMC8741373__F11 Identification of Potential Biomarkers of Depression and Network Pharmacology Approach to Investigate the Mechanism of Key Genes and Therapeutic Traditional Chinese Medicine in the Treatment of Depression ENSG00000111837 ENSG00000174197 ENSG00000131323 PMC10094755__F6 Metabolic pathway of 17Beta-estradiol biosynthesis ENSG00000086696 ENSG00000108786 ENSG00000203859 ENSG00000203857 PMC10539668__F8 TNFA counteracts interleukin-10 anti-inflammatory pathway through the NOX2-Lyn-SHP-1 axis in human monocytes ENSG00000105397 ENSG00000168610 PMC9331798__F7 Artemisinin relieves osteoarthritis by activating mitochondrial autophagy through reducing TNFSF11 expression and inhibiting PI3K/AKT/mTOR signaling in cartilage ENSG00000125538 ENSG00000198793 PMC5689582__F3 Increased transcriptional and metabolic capacity for lipid metabolism in the peripheral zone of the prostate may underpin its increased susceptibility to cancer ENSG00000057252 ENSG00000001630 ENSG00000116133 ENSG00000172893 ENSG00000149809 ENSG00000109929 ENSG00000019186 ENSG00000104549 ENSG00000052802 ENSG00000186104 PMC11833111__F5 Correlation analysis of differential microbiota, metabolites, proteins and FST ENSG00000136960 ENSG00000134363 ENSG00000153395 ENSG00000130653 PMC8535226__F2 Expression of Cytokine-Coding Genes BMP8B, LEFTY1 and INSL5 Could Distinguish between Ulcerative Colitis and Crohn’s Disease ENSG00000049323 ENSG00000137834 ENSG00000156574 ENSG00000134363 ENSG00000067900 ENSG00000205250 ENSG00000137801 ENSG00000170365 ENSG00000111537 ENSG00000095739 ENSG00000100387 ENSG00000198742 ENSG00000113558 ENSG00000164093 ENSG00000185591 PMC7830467__F1 Ubiquitin signaling in the tumor microenvironment (TME) ENSG00000087245 PMC4472614__F4 Functional relations of differentially expressed genes with each other and with members of important pathways, as displayed by FunCoup online resource ENSG00000160789 ENSG00000197471 ENSG00000119969 ENSG00000173402 ENSG00000114857 ENSG00000134531 PMC4451739__F2 Complement during infection with a pathogen ENSG00000039537 ENSG00000113600 ENSG00000236625 PMC3042730__F2 Inflammatory signals regulate hematopoietic stem cells ENSG00000159128 ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000102871 ENSG00000027697 ENSG00000172936 ENSG00000175104 ENSG00000127191 ENSG00000142166 PMC11885647__F6 Stem cell exhaustion and intercellular communication regulated by redox signaling ENSG00000126016 ENSG00000186575 ENSG00000010810 ENSG00000163914 ENSG00000168036 ENSG00000164690 ENSG00000128602 ENSG00000131023 ENSG00000079999 PMC11885647__F5 Redox signaling modulates metabolic reprogramming ENSG00000107745 ENSG00000156026 ENSG00000169047 PMC11885647__F4 Redox regulation of proteolysis ENSG00000107669 ENSG00000159335 PMC4793894__F3 PPAR signaling pathway ENSG00000166819 ENSG00000140992 ENSG00000151726 ENSG00000135218 ENSG00000167114 ENSG00000167910 ENSG00000165269 ENSG00000173391 ENSG00000099194 ENSG00000132170 ENSG00000157184 ENSG00000065833 ENSG00000117054 ENSG00000167772 ENSG00000150991 ENSG00000134824 ENSG00000161533 ENSG00000180432 ENSG00000100979 ENSG00000115361 ENSG00000158874 ENSG00000124253 ENSG00000083807 ENSG00000135929 PMC7037237__F1 Simplified schematic of type-I IFN induction and major IFNAR signaling pathways ENSG00000213928 ENSG00000239732 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000125347 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC6814307__F1 Vitamin D metabolic pathway ENSG00000111012 ENSG00000118972 ENSG00000152266 ENSG00000019186 ENSG00000186104 PMC8635790__F5 Selenotranscriptome Network in Non-alcoholic Fatty Liver Disease ENSG00000138449 ENSG00000164398 ENSG00000179918 ENSG00000110911 PMC3481284__F8 Schematic diagram of CaMKII regulates Notch1 signaling through proteasomal degradation of SMRT ENSG00000148400 ENSG00000273529 ENSG00000114315 PMC6953115__F2 Epac1 signalosome in cardiac stress conditions ENSG00000138741 ENSG00000108840 PMC6780103__F4 Human adenovirus induced cell signaling and downstream immune responses in human keratocytes, highlighting the centrality of Src kinase ENSG00000174125 ENSG00000239732 ENSG00000291971 ENSG00000117335 ENSG00000172936 PMC3230686__F3 Induction of regulatory Tr1 cells and inhibition of TH17 cells by IL-27 ENSG00000159216 ENSG00000178573 ENSG00000115415 ENSG00000049768 ENSG00000168610 ENSG00000106546 PMC5927979__F2 Interaction network of microRNAs identified potential mRNA targets involved in clinical features of antiphospholipid syndrome ENSG00000177570 ENSG00000167601 ENSG00000171105 ENSG00000128512 ENSG00000103710 ENSG00000095951 ENSG00000173482 ENSG00000112992 ENSG00000112715 ENSG00000197702 ENSG00000108691 ENSG00000112242 ENSG00000154065 ENSG00000171634 ENSG00000133812 ENSG00000005893 ENSG00000136160 ENSG00000204217 PMC8825490__F1 Macrophage Immunometabolism: A New Approach to Fight Infections ENSG00000168003 ENSG00000100412 ENSG00000105953 ENSG00000026103 PMC8245300__F5 ATRX-dependent mechanisms in physiology, cancer and human genetic disease ENSG00000084093 ENSG00000113648 PMC4225461__F1 Statistically significant signaling pathway networks between JU and vehicle groups ENSG00000124535 ENSG00000104899 ENSG00000125740 ENSG00000122420 ENSG00000138772 ENSG00000011132 ENSG00000120875 ENSG00000197632 ENSG00000180772 ENSG00000162772 ENSG00000166068 ENSG00000113328 ENSG00000138613 ENSG00000205155 ENSG00000132855 ENSG00000135828 ENSG00000126264 ENSG00000105821 PMC8216565__F8 PI3K-AKT signaling pathway ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000162924 PMC4424001__F2 Hierarchical Feedback Modules and Reaction Hubs in Cell Signaling Networks ENSG00000169291 ENSG00000149782 ENSG00000146648 PMC8216565__F9 MAPK signaling pathway ENSG00000087095 ENSG00000142192 ENSG00000101474 ENSG00000170458 ENSG00000105656 ENSG00000115718 ENSG00000127191 ENSG00000026103 PMC3879958__F1 Regulating the Regulator: Post-Translational Modification of Ras ENSG00000156299 ENSG00000196712 PMC2671025__F6 Role of adiponectin in human skeletal muscle bioenergetics ENSG00000159346 ENSG00000285070 ENSG00000081189 PMC4023229__F2 Neural tube defects – recent advances, unsolved questions and controversies ENSG00000164932 ENSG00000198742 ENSG00000120057 ENSG00000173218 ENSG00000112655 ENSG00000104332 PMC11375541__F10 Dual functionality of necroptosis in CC patients ENSG00000169248 ENSG00000169245 ENSG00000138755 ENSG00000112715 PMC2696553__F1 Store-operated Ca2+ entry in T cells ENSG00000213658 ENSG00000293604 ENSG00000049768 PMC7411728__F2 Inflammation, innate immunity, and adaptive immunity by CH25H and 25HC ENSG00000150782 ENSG00000138135 ENSG00000125538 PMC8650046__F3 Circular RNA‐associated ceRNA network involved in HIF‐1 signalling in triple‐negative breast cancer: circ_0047303 as a potential key regulator ENSG00000159128 ENSG00000171105 ENSG00000005339 ENSG00000109320 ENSG00000072274 ENSG00000173039 ENSG00000027697 ENSG00000171791 ENSG00000091879 ENSG00000112715 ENSG00000168610 ENSG00000124762 ENSG00000175634 ENSG00000117020 ENSG00000134086 ENSG00000114268 ENSG00000136869 ENSG00000124181 ENSG00000146648 ENSG00000159399 PMC9099016__F3 LncRNAs and CircRNAs in cancer ENSG00000118971 PMC6678715__F3 FGFR signaling pathway PMC2910728__F6 Absence of Inhibin Alpha and Retinoblastoma Protein Leads to Early Sertoli Cell Dysfunction ENSG00000105327 ENSG00000135446 ENSG00000120868 ENSG00000118971 PMC7538694__F7 BMP signaling pathway in mouse and zebrafish ENSG00000170365 ENSG00000125968 PMC7145763__F5 Human BNB junction complex formation: The GDNF-CREB1-SRC-CTTN/CTNNA1/CLDN4-SEC31A hypothesis ENSG00000138674 ENSG00000044115 ENSG00000291971 PMC9101234__F6 Cardiac Fibroblast GLS1 Expression by Scleraxis ENSG00000115419 ENSG00000167701 PMC8584118__F2A Nod-like Receptors: Critical Intracellular Sensors for Host Protection and Cell Death in Microbial and Parasitic Infections ENSG00000104856 ENSG00000142405 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC9299562__F3 Integrated bioinformatics analysis of validated and circulating miRNAs in ovarian cancer ENSG00000127948 PMC4899597__F1 Canonical Wnt signalling involves binding of Wnt to LRP5/6 and its coreceptor Frizzled resulting in the phosphorylation of LRP5/6 thus permitting Axin to bind to the receptor complex ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000167074 PMC8013908__F1 COVID‐19: immunopathology, pathophysiological mechanisms, and treatment options ENSG00000140564 ENSG00000196591 ENSG00000276561 ENSG00000183735 ENSG00000130234 ENSG00000125538 ENSG00000184012 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC3774073__F1 Phosphorylation events and the modulation of aquaporin 2 cell surface expression ENSG00000167580 ENSG00000172005 ENSG00000145321 PMC9405025__F3 Yeast Beta-Glucans as Fish Immunomodulators: A Review ENSG00000110244 ENSG00000125538 ENSG00000172936 PMC2981507__F2 Therapeutic interventions for fragile X syndrome ENSG00000198793 PMC3176306__F1 New strategies in Prostate Cancer: targeting lipogenic pathways and the energy sensor AMPK ENSG00000131473 ENSG00000198793 ENSG00000169710 PMC3075259__F4 Data Integration Workflow for Search of Disease Driving Genes and Genetic Variants ENSG00000134057 ENSG00000116984 ENSG00000198625 PMC8497523__F7 Identification of biomarkers of brown adipose tissue aging highlights the role of dysfunctional energy and nucleotide metabolism pathways ENSG00000128050 ENSG00000162368 ENSG00000178035 ENSG00000165609 ENSG00000156110 ENSG00000103024 ENSG00000169299 ENSG00000113448 ENSG00000133805 PMC5569249__F1 miRNA pathways in myeloid differentiation and myeloid-derived malignancies ENSG00000159388 ENSG00000198793 PMC5660697__F1 JNK signaling pathway ENSG00000189403 PMC5082882__F1 Estrogen Enhances the Expression of the Polyunsaturated Fatty Acid Elongase Elovl2 via ERA in Breast Cancer Cells ENSG00000134824 ENSG00000149485 ENSG00000197977 PMC5569249__F2 miRNA pathways in mature immune cell function ENSG00000125538 ENSG00000134070 ENSG00000172936 ENSG00000184216 PMC9139060__F2 Low-Grade Inflammation in the Pathogenesis of Osteoarthritis: Cellular and Molecular Mechanisms and Strategies for Future Therapeutic Intervention ENSG00000151702 ENSG00000162711 ENSG00000189403 ENSG00000172936 ENSG00000175104 PMC9124082__F7 Marine-Derived Stichloroside C2 Inhibits Epithelial–Mesenchymal Transition and Induces Apoptosis through the Mitogen-Activated Protein Kinase Signalling Pathway in Triple-Negative Breast Cancer Cells ENSG00000134057 ENSG00000123374 ENSG00000166278 PMC3995458__F1 Biosynthetic pathways of glycerophospholipids ENSG00000087253 ENSG00000173599 ENSG00000111684 ENSG00000198670 ENSG00000153395 ENSG00000184207 ENSG00000123684 PMC5395355__F2 Phosphopeptides from the MOE and FOE phosphoproteomes are represented in some distinct signaling pathways, including Rho signaling for MOE (A), GABA signaling for FOE (B) and amyloid processing for FOE (C) ENSG00000142192 ENSG00000171723 ENSG00000163914 ENSG00000092820 PMC5661483__F12 10H-3,6-Diazaphenothiazine induces G2/M phase cell cycle arrest and caspase-dependent apoptosis and inhibits cell invasion of A2780 ovarian carcinoma cells through the regulation of NFKB and (BIRC6-XIAP) complexes ENSG00000023445 ENSG00000110330 ENSG00000089685 ENSG00000102871 ENSG00000116717 ENSG00000168040 ENSG00000140443 ENSG00000115760 ENSG00000026103 ENSG00000276068 ENSG00000160049 PMC7828503__F3 Signaling lymphocytic activation molecule family receptor (SLAMF) 3 signal transduction is mediated via self-ligation and cell–cell interactions ENSG00000134982 ENSG00000010810 ENSG00000166278 PMC3312283__F2 This figure shows three novel intracellular signaling pathways involved in the pathogenesis of IBD ENSG00000125538 ENSG00000162692 ENSG00000168610 PMC7102672__F6 Enriched DGEs in the p53 signaling pathway The DGSs included in the CG vs HS groups, and CG vs HR groups are shown ENSG00000149311 ENSG00000132906 ENSG00000175054 ENSG00000002330 ENSG00000123374 ENSG00000112378 ENSG00000196470 ENSG00000164305 PMC7102672__F5 Enriched DGEs in the PPAR signaling pathway There were three pairwise comparison groups (CG vs HS, CG vs HR and HS vs HR) in our study, and there were three kinds of DEGs from the different comparison groups ENSG00000150991 ENSG00000115266 ENSG00000100979 ENSG00000165269 PMC12191391__F4 TR2/TR4-mediated regulatory pathway in heme biosynthesis ENSG00000102145 ENSG00000158578 PMC3905307__F1 Canonical (A) and noncanonical (B) Wnt signaling pathway represented by KEGG analysis ENSG00000166869 ENSG00000087095 ENSG00000166167 ENSG00000188386 ENSG00000156076 ENSG00000137673 ENSG00000134982 ENSG00000165059 ENSG00000196470 ENSG00000104332 ENSG00000100888 ENSG00000072803 ENSG00000163904 ENSG00000148660 ENSG00000100592 ENSG00000101849 ENSG00000169750 ENSG00000155011 ENSG00000113558 ENSG00000177606 ENSG00000161202 ENSG00000101333 PMC8435845__F3 Research Progress on the Structure and Function of G3BP ENSG00000087245 ENSG00000069482 ENSG00000184995 ENSG00000118785 PMC8153896__F4 Molecular Dynamics-Based Allosteric Prediction Method to Design Key Residues in Threonine Dehydrogenase for Amino-Acid Production ENSG00000128928 PMC6562660__F2 Downstream effector proteins of the major Rho GTPases, Rac1, Cdc42, and RhoA ENSG00000070831 ENSG00000163914 ENSG00000084112 PMC2815188__F2 This presentation will focus on molecular mechanisms underlying transduction of BCR signals that enforce the antigen unresponsiveness of anergic B cells ENSG00000121966 PMC8062726__F7 Summary of the regulated pathways during DCs-T ENSG00000213928 ENSG00000105835 ENSG00000167207 ENSG00000187608 ENSG00000089127 ENSG00000157601 ENSG00000160710 ENSG00000088256 ENSG00000265972 ENSG00000067369 ENSG00000239732 ENSG00000134321 ENSG00000184995 ENSG00000138755 ENSG00000140464 ENSG00000113889 ENSG00000107404 ENSG00000125826 ENSG00000137275 ENSG00000137033 ENSG00000289721 ENSG00000127955 ENSG00000185745 ENSG00000027697 ENSG00000127666 ENSG00000125347 ENSG00000162654 ENSG00000276561 ENSG00000007171 ENSG00000169245 ENSG00000117226 ENSG00000105397 ENSG00000131323 ENSG00000111331 ENSG00000121060 ENSG00000204397 ENSG00000278718 ENSG00000051523 ENSG00000171855 ENSG00000169248 ENSG00000135218 ENSG00000102871 ENSG00000291971 ENSG00000163568 ENSG00000168811 ENSG00000183850 ENSG00000150782 ENSG00000088888 ENSG00000263528 ENSG00000147896 ENSG00000168398 ENSG00000164342 ENSG00000174125 ENSG00000168040 ENSG00000168610 ENSG00000137841 ENSG00000111537 ENSG00000115415 ENSG00000135114 ENSG00000100348 ENSG00000135828 ENSG00000131196 PMC9465172__F2 Exposure of metal toxicity in Alzheimer’s disease: An extensive review ENSG00000142192 ENSG00000173992 ENSG00000138495 ENSG00000123191 PMC8611230__F1 Melanoma susceptibility: an update on genetic and epigenetic findings ENSG00000149311 ENSG00000163930 ENSG00000135446 ENSG00000105810 ENSG00000166848 ENSG00000128513 ENSG00000102977 PMC8062726__F5 Protein-protein interaction underlines genes from virus response as network-hubs ENSG00000173821 ENSG00000185608 ENSG00000213928 ENSG00000183486 ENSG00000230034 ENSG00000158042 ENSG00000134326 ENSG00000138755 ENSG00000185404 ENSG00000132109 ENSG00000125826 ENSG00000117228 ENSG00000125148 ENSG00000196954 ENSG00000166889 ENSG00000185885 ENSG00000114127 ENSG00000043462 ENSG00000132792 ENSG00000276561 ENSG00000169715 ENSG00000169245 ENSG00000275214 ENSG00000117226 ENSG00000185201 ENSG00000123609 ENSG00000059378 ENSG00000121060 ENSG00000204397 ENSG00000169248 ENSG00000157933 ENSG00000135899 ENSG00000101596 ENSG00000163840 ENSG00000125144 ENSG00000108679 ENSG00000125538 ENSG00000124201 ENSG00000002549 ENSG00000272886 ENSG00000164342 ENSG00000026103 ENSG00000124256 ENSG00000172869 ENSG00000115008 ENSG00000130589 ENSG00000073756 ENSG00000277943 ENSG00000184979 ENSG00000108691 ENSG00000067066 ENSG00000115956 ENSG00000164691 ENSG00000117091 ENSG00000135114 ENSG00000164136 ENSG00000291555 ENSG00000142089 ENSG00000205364 ENSG00000138385 PMC9735758__F1 IL-1RAP, a Key Therapeutic Target in Cancer ENSG00000137033 ENSG00000125538 ENSG00000136696 ENSG00000136694 ENSG00000172936 ENSG00000185187 ENSG00000168610 ENSG00000115607 PMC3381230__F2 Major mechanisms of immune modulation by tolerogenic DCs ENSG00000138378 ENSG00000145777 PMC5621151__F1 TLR-signaling pathways ENSG00000169245 ENSG00000183735 ENSG00000170458 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC10526161__F1 Integrated Multi-Omics Profiling of Young Breast Cancer Patients Reveals a Correlation between Galactose Metabolism Pathway and Poor Disease-Free Survival ENSG00000121879 PMC5930279__F1 Effects of choline in lipid metabolism pathway ENSG00000173599 ENSG00000026103 ENSG00000133027 PMC3681204__F3 Systems Scale Interactive Exploration Reveals Quantitative and Qualitative Differences in Response to Influenza and Pneumococcal Vaccines ENSG00000166579 ENSG00000011600 ENSG00000187608 ENSG00000101307 ENSG00000089127 ENSG00000157601 ENSG00000160710 ENSG00000278211 ENSG00000171051 ENSG00000134321 ENSG00000172216 ENSG00000188313 ENSG00000156587 ENSG00000142405 ENSG00000275565 ENSG00000140464 ENSG00000132109 ENSG00000125826 ENSG00000154589 ENSG00000117228 ENSG00000119535 ENSG00000162551 ENSG00000184014 ENSG00000185745 ENSG00000221869 ENSG00000213341 ENSG00000162654 ENSG00000276561 ENSG00000154451 ENSG00000169245 ENSG00000187554 ENSG00000123609 ENSG00000133961 ENSG00000111331 ENSG00000204397 ENSG00000163568 ENSG00000232326 ENSG00000203710 ENSG00000124107 ENSG00000137959 ENSG00000132530 ENSG00000157557 ENSG00000168461 ENSG00000144848 ENSG00000110446 ENSG00000115271 ENSG00000292357 ENSG00000090376 ENSG00000124256 ENSG00000099985 ENSG00000115267 ENSG00000060558 ENSG00000285456 ENSG00000166401 ENSG00000172183 ENSG00000163625 ENSG00000115415 ENSG00000135114 ENSG00000291555 ENSG00000142089 ENSG00000100365 ENSG00000159399 PMC5793162__F1 Cancer cell signaling and regulation of alternative splicing ENSG00000115875 ENSG00000132906 ENSG00000011304 ENSG00000157764 ENSG00000134982 ENSG00000198793 ENSG00000026508 ENSG00000168036 PMC6094676__F1 Oncogene-directed small molecule inhibitors for the treatment of cutaneous melanoma ENSG00000157404 ENSG00000002330 ENSG00000157764 ENSG00000135446 ENSG00000198793 ENSG00000281877 ENSG00000171791 ENSG00000196712 ENSG00000198625 PMC2683622__F9 Protein kinase D1 is essential for MyD88-dependent TLR signaling pathway ENSG00000008710 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC3979852__F8 Chemokine Receptor CCR8 Is Required for Lipopolysaccharide-Triggered Cytokine Production in Mouse Peritoneal Macrophages ENSG00000108702 ENSG00000179934 ENSG00000136869 PMC12202659__F7 Representative molecular pathways of breast cancer induction by PCBs compound exposure ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000198517 ENSG00000104894 ENSG00000127191 PMC2773711__F1 Canonical TCR signaling pathway ENSG00000010810 ENSG00000177606 ENSG00000162924 ENSG00000113263 PMC6092802__F7 DNA Damage Response (DDR) Pathway ENSG00000012048 ENSG00000276618 ENSG00000113456 ENSG00000149554 ENSG00000183765 PMC6387166__F1 Effects of distinct molecules produced by stressed cancer cells on NK cell-mediated functions ENSG00000164430 PMC1201361__F6 Anandamide as an intracellular messenger inducing Ca2+ influx via TRPV1 ENSG00000117480 ENSG00000145020 ENSG00000196689 PMC5996766__F1 Of Pleiotropy and Trajectories: Does the TGFB Pathway Link Childhood Asthma and COPD? ENSG00000137834 ENSG00000160973 ENSG00000157933 ENSG00000105329 ENSG00000107249 ENSG00000198742 ENSG00000020633 ENSG00000175104 ENSG00000276561 ENSG00000106546 PMC4205566__F1 A Signaling Network Induced by B2 Integrin Controls the Polarization of Lytic Granulesin Cytotoxic Cells ENSG00000110031 ENSG00000111859 ENSG00000102606 ENSG00000134215 ENSG00000169756 ENSG00000115904 ENSG00000115598 ENSG00000043462 ENSG00000173517 ENSG00000138964 ENSG00000089159 ENSG00000149311 ENSG00000203747 ENSG00000101310 ENSG00000111796 ENSG00000186635 ENSG00000120899 ENSG00000087589 ENSG00000136527 ENSG00000135605 ENSG00000141367 PMC4374437__F6 Schematic diagram illustrating intracellular signaling pathways in a macrophage involved in cytokine regulation by adrenergic and cholinergic agonists and receptors following lipopolysaccharide challenge ENSG00000189403 ENSG00000168610 PMC6608985__F15 Autocrine STAT3 activation in HPV positive cervical cancer through a virus-driven Rac1—NFKB—IL-6 signalling axis ENSG00000168610 PMC7555565__F3 Mechanistic network showing the highest score for a set of significantly differentially expressed genes in MG (methylglyoxal)-treated rats ENSG00000169554 ENSG00000065518 ENSG00000143507 ENSG00000114737 ENSG00000169047 ENSG00000136111 ENSG00000164938 ENSG00000170653 ENSG00000116741 ENSG00000073417 PMC4887618__F5 The working model of STAT3 and AvrA interaction in chronic intestinal Salmonella infected in colon cancer ENSG00000137673 ENSG00000168036 ENSG00000168610 PMC7555565__F5 Adverse Effects of Methylglyoxal on Transcriptome and Metabolic Changes in Visceral Adipose Tissue in a Prediabetic Rat Model ENSG00000291431 ENSG00000169047 PMC3818842__F6 Major apoptotic pathways in SGNs induced by oubain treatment ENSG00000168040 PMC7865314__F4 Optimising radiation dose and delivery for optimal immunogenicity ENSG00000134982 ENSG00000026103 PMC8463930__F8 Network Pharmacology Reveals That Resveratrol Can Alleviate COVID-19-Related Hyperinflammation ENSG00000169291 ENSG00000226275 ENSG00000170458 ENSG00000198517 ENSG00000172936 ENSG00000007908 ENSG00000131323 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000127191 ENSG00000127948 PMC9253705__F7 Pexmetinib suppresses osteoclast formation and breast cancer induced osteolysis via P38/STAT3 signal pathway ENSG00000087245 ENSG00000168610 ENSG00000131196 ENSG00000143387 PMC8044831__F1 Anti-inflammatory mediated effects of phytochemicals along the TLR4 signaling pathway ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC6586490__F1 Mitochondrial dysfunctions in Barth syndrome ENSG00000087157 ENSG00000184207 PMC7500008__F2 Targets of overexpressed (a) and downregulated (b) microRNAs (N1 versus N0) among genes participating cell cycle progression and regulation (KEGG pathway hsa04110 – cell cycle) ENSG00000145604 ENSG00000124102 ENSG00000105664 ENSG00000132646 ENSG00000125686 ENSG00000123374 ENSG00000277273 ENSG00000276876 PMC2733244__F2 Bridging the gap between high-throughput genetic and transcriptional data reveals cellular pathways responding to alpha-synuclein toxicity ENSG00000261832 ENSG00000288283 ENSG00000163918 ENSG00000100219 ENSG00000133119 ENSG00000197601 PMC3061395__F10 The bifurcating parallel signal transduction pathways downstream of the IL-13R that regulate 15-LO gene expression in primary human monocytes ENSG00000105397 ENSG00000131724 ENSG00000168610 PMC7580956__F4 Carbon metabolism in the plastids of E ENSG00000197713 ENSG00000182511 ENSG00000153574 ENSG00000184207 PMC6755513__F10 Schematic chart showing the molecular pathway for Mg2+‐regulated endothelial barrier function ENSG00000092439 ENSG00000102158 ENSG00000119121 PMC5103369__F6 Regulatory roles of the Arg/N-end rule pathway in autophagic flux and protein aggregate clearance ENSG00000284099 ENSG00000197386 ENSG00000107669 PMC3466494__F1 GSK3 regulates a variety of pathways involved in neurodevelopment ENSG00000124102 ENSG00000134982 ENSG00000168036 PMC4515826__F7 Genome-wide mutational spectra analysis reveals significant cancer-specific heterogeneity ENSG00000157404 ENSG00000143341 ENSG00000168702 ENSG00000198793 ENSG00000168036 ENSG00000067798 ENSG00000121879 ENSG00000145113 ENSG00000169436 ENSG00000134086 ENSG00000186575 ENSG00000170927 ENSG00000073614 ENSG00000176406 ENSG00000155657 ENSG00000042781 ENSG00000293532 ENSG00000198286 ENSG00000109670 ENSG00000100285 ENSG00000005339 ENSG00000157764 ENSG00000154358 ENSG00000292167 ENSG00000164796 ENSG00000157423 ENSG00000198626 ENSG00000269699 ENSG00000105568 ENSG00000124721 ENSG00000079999 ENSG00000149311 ENSG00000183337 ENSG00000196218 ENSG00000107611 ENSG00000198597 ENSG00000170396 ENSG00000102974 PMC5008362__F1 Exploring the role of sphingolipid machinery during the epithelial to mesenchymal transition program using an integrative approach ENSG00000285281 ENSG00000174607 ENSG00000135587 ENSG00000143418 ENSG00000139624 ENSG00000100422 ENSG00000138744 ENSG00000198964 ENSG00000063176 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000292130 ENSG00000164023 ENSG00000166224 ENSG00000148154 ENSG00000163082 PMC5721467__F9 Regulatory network elicited by nuclear translocation of syndecan-1 leading to inhibition of proliferation and survival ENSG00000135903 ENSG00000185591 PMC6017063__F1 Therapeutic targets in the Notch signaling pathway ENSG00000128917 ENSG00000184916 ENSG00000090932 PMC7709037__F3 Merging network associated with the EGFR/ERBB2 signaling pathway by IPA-identified three networks (#1, #5, and #12 in ) ENSG00000009724 ENSG00000154133 ENSG00000146648 ENSG00000197702 PMC7761891__F3 Effects of extracellular nutrients on mitochondria could activate the integrated stress response (ISR) pathway in cancer ENSG00000128272 ENSG00000144895 ENSG00000162600 ENSG00000081791 PMC3687803__F3 Canonical wnt signaling pathway ENSG00000134982 PMC5048723__F4 Signaling pathways associated with differentially methylated candidate genes were predicted by Ingenuity Pathway Analysis™ ENSG00000169105 ENSG00000076554 ENSG00000169884 PMC3934644__F1 Regulation and effectors of the mTOR signaling pathway ENSG00000002330 ENSG00000123374 PMC5732234__F2 The immune deficiency (IMD) pathway in fruit fly and the TNF pathway in the mouse ENSG00000173039 ENSG00000162924 ENSG00000168040 ENSG00000127191 PMC9396912__F2 Ferroptosis in esophageal cancer ENSG00000168003 ENSG00000159128 ENSG00000111537 ENSG00000151012 ENSG00000115415 ENSG00000167468 ENSG00000027697 PMC10025411__F1 Neuroprotective effects of targeting key factors of neuronal cell death in neurodegenerative diseases: The role of ER stress, oxidative stress, and neuroinflammation ENSG00000128272 ENSG00000101255 ENSG00000100219 PMC4786079__F4 Fever and the thermal regulation of immunity: the immune system feels the heat ENSG00000115415 ENSG00000168610 PMC4040260__F2 Apoptotic cell clearance: basic biology and therapeutic potential ENSG00000198053 ENSG00000189403 PMC3404876__F2 Identification of novel metastasis suppressor signaling pathways for breast cancer ENSG00000121966 ENSG00000156273 PMC7746343__F8 ATR-CHK1 and ATM-CHK2 in the cell cycle pathway ENSG00000149311 ENSG00000175054 ENSG00000123374 ENSG00000101224 PMC3091695__F3 Stress-induced pathways in the PVN of the hypothalamus of DBA/2J (A) and C57BL/6 (B) mice ENSG00000136158 ENSG00000142192 ENSG00000138798 ENSG00000116741 ENSG00000131196 PMC5732234__F1 Toll pathway in fruit fly and the Toll-like receptor (TLR) 4 pathway in the mouse ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC3193452__F1 Regulated necrosis in the intestine of FADDIEC-KO mice ENSG00000125538 ENSG00000172936 ENSG00000083799 ENSG00000168040 PMC6818007__F3 VEGF (vascular endothelial growth factor)‐angiogenesis signaling and cell cycle regulation pathways ENSG00000291971 ENSG00000198793 ENSG00000158458 ENSG00000164327 ENSG00000112715 ENSG00000149311 ENSG00000175054 ENSG00000128052 ENSG00000136997 ENSG00000123374 ENSG00000124181 ENSG00000146648 ENSG00000128513 PMC4980330__F2 Regulation of the Hippo pathway by multiple upstream signals ENSG00000163914 ENSG00000113161 ENSG00000166025 ENSG00000198670 ENSG00000150457 ENSG00000131023 PMC4980330__F1 The core of the Hippo signaling pathway ENSG00000131023 PMC6818007__F1 Telomere biology and damage signaling ENSG00000166340 ENSG00000149311 ENSG00000175054 ENSG00000123374 ENSG00000128513 PMC7833179__F1 Could Oral Phosphodiesterase 5 Inhibitors Have a Potential Adjuvant Role in Combating COVID-19 Infection? ENSG00000137033 ENSG00000100219 ENSG00000171791 ENSG00000096717 ENSG00000142082 ENSG00000135517 PMC7396774__F5 Re-analysis of 14 selected genes using KEGG pathway enrichment ENSG00000108055 ENSG00000134982 ENSG00000205250 ENSG00000277273 ENSG00000117399 ENSG00000276876 ENSG00000093009 ENSG00000145604 ENSG00000094804 ENSG00000135446 ENSG00000132646 ENSG00000115942 ENSG00000123374 ENSG00000105810 PMC5647956__F1 Artemisinin biosynthetic pathway in A ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC5721467__F4 Upstream regulators and downstream biological effects predicted by Ingenuity Pathway Analysis on the proteome level ENSG00000123496 ENSG00000105329 ENSG00000086991 ENSG00000056558 ENSG00000185532 ENSG00000108342 ENSG00000116741 PMC9032679__F2 Extracellular Vesicle-Mediated Mitochondrial Reprogramming in Cancer ENSG00000116688 ENSG00000171109 PMC3817541__F1 Mechanism of activity-dependent transcriptional repression by MeCP2 ENSG00000174576 PMC9580888__F4 Sphingosine‐1‐phosphate‐lyase deficiency affects glucose metabolism in a way that abets oncogenesis ENSG00000198793 ENSG00000183018 ENSG00000137642 PMC2651818__F3 Activity motifs reveal principles of timing in transcriptional control of the yeast metabolic network ENSG00000111231 ENSG00000142751 PMC9570456__F2 Adenosine, Schizophrenia and Cancer: Does the Purinergic System Offer a Pathway to Treatment? ENSG00000156110 ENSG00000196839 PMC7190945__F2 VSL#3 on intestinal barrier function ENSG00000115415 PMC7246584__F1 Interplay between HCV-induced oncogenic signaling pathways ENSG00000138798 ENSG00000110651 ENSG00000168610 ENSG00000146648 PMC7352559__F2A Klotho and the Treatment of Human Malignancies ENSG00000135655 ENSG00000134982 ENSG00000169047 ENSG00000198793 ENSG00000168036 PMC5394902__F2 Canonical pathway and upstream regulator effects analysis identifies inflammatory response, migration, and proliferation pathways enriched in trkB.T1 KO astrocytes ENSG00000169896 ENSG00000073756 ENSG00000132170 PMC8373118__F4 Key Considerations for the Development of Safe and Effective SARS‐CoV‐2 Subunit Vaccine: A Peptide‐Based Vaccine Alternative ENSG00000088888 ENSG00000172936 ENSG00000131323 ENSG00000276561 PMC5877662__F3 cGMP signaling pathway ENSG00000145321 ENSG00000096088 ENSG00000214285 PMC3687803__F1 Different layers of the epidermis, and the functions within those layers regulated by VDR and its coactivators ENSG00000118402 ENSG00000170458 ENSG00000291971 ENSG00000148154 ENSG00000143631 PMC7409063__F1 Extracellular vesicle (EV) biogenesis and signaling between neighboring cells ENSG00000111737 PMC8740576__F5 HIV-1 hypermethylated guanosine cap licenses specialized translation unaffected by mTOR ENSG00000198793 ENSG00000137574 ENSG00000074356 PMC9060113__F2 Targeting the PI3K/Akt signaling pathway in pancreatic B‐cells to enhance their survival and function: An emerging therapeutic strategy for type 1 diabetes ENSG00000111537 ENSG00000125538 PMC11670804__F5 Visualization of GO terms and DETs connected to the development of HFs in sheep ENSG00000162711 ENSG00000175893 ENSG00000134569 ENSG00000175065 ENSG00000265972 ENSG00000168615 ENSG00000179593 ENSG00000064300 ENSG00000117054 ENSG00000125398 ENSG00000184384 ENSG00000196498 ENSG00000027075 ENSG00000197713 ENSG00000175793 ENSG00000183077 ENSG00000137841 ENSG00000171446 ENSG00000292027 ENSG00000125780 ENSG00000123364 ENSG00000134824 ENSG00000198728 ENSG00000131196 ENSG00000127616 PMC9316611__F2 Indoor Secondary Pollutants Cannot Be Ignored: Third-Hand Smoke ENSG00000138798 ENSG00000177606 ENSG00000136997 ENSG00000149273 ENSG00000171791 ENSG00000146648 PMC8643499__F7 Loss of Zic3 impairs planar cell polarity leading to abnormal left–right signaling, heart defects and neural tube defects ENSG00000163637 ENSG00000004975 ENSG00000107404 ENSG00000100592 ENSG00000173218 ENSG00000143126 ENSG00000156925 ENSG00000177606 ENSG00000075275 ENSG00000008300 ENSG00000161202 PMC2869400__F9 A model of Gfi-1-mediated repression of CDKN1A and other Miz-1 target genes ENSG00000162676 ENSG00000136997 ENSG00000124762 PMC9323599__F3 Edwardsiella ictaluri T3SS Effector EseN Modulates Expression of Host Genes Involved in the Immune Response ENSG00000239732 ENSG00000170458 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC10149954__F2 Receptors that bind to PEDF and their therapeutic roles in retinal diseases ENSG00000087245 ENSG00000281324 ENSG00000137673 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000100985 PMC9060113__F1 Targeting the PI3K/Akt signaling pathway in pancreatic B‐cells to enhance their survival and function: An emerging therapeutic strategy for type 1 diabetes ENSG00000002330 ENSG00000081913 ENSG00000040199 PMC9652959__F2 Recent advances on small molecules in osteogenic differentiation of stem cells and the underlying signaling pathways ENSG00000087095 ENSG00000170365 ENSG00000137834 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC11357207__F4 Working model to propose ABC-transporter mediated cholesterol efflux reduces the pro-inflammatory immune response that initially occurs from T ENSG00000136869 ENSG00000160179 PMC9652959__F4 Recent advances on small molecules in osteogenic differentiation of stem cells and the underlying signaling pathways ENSG00000168283 ENSG00000163914 ENSG00000177606 ENSG00000175104 PMC6406942__F2 Base Excision Repair (BER) in mitochondria ENSG00000109674 ENSG00000292286 ENSG00000115008 ENSG00000039650 ENSG00000123415 ENSG00000140398 PMC7432774__F1 Biology of tumor hypoxia ENSG00000128272 ENSG00000198793 ENSG00000100219 PMC3025384__F2 JAK/STAT3 signaling pathway transmits information from cytokine/chemical signals outside the cell, through the cell membrane, and into the gene promoters on the DNA in the cell nucleus, which causes DNA transcription and activity in the cell ENSG00000087095 ENSG00000198793 ENSG00000168036 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000168610 PMC8174842__F5 Dickkopf-1: A Promising Target for Cancer Immunotherapy ENSG00000136026 PMC3025384__F3 Wnt signaling plays central role in embryogenesis and human diseases including cancers ENSG00000002330 ENSG00000102871 ENSG00000177606 ENSG00000168036 ENSG00000171791 ENSG00000175104 ENSG00000127191 ENSG00000146648 PMC3724399__F1 PI3K/Akt/mTOR pathway PMC8508518__F2 Impact of STAT Proteins in Tumor Progress and Therapy Resistance in Advanced and Metastasized Prostate Cancer ENSG00000291971 PMC8147235__F2 Neuroinflammation in Sepsis: Molecular Pathways of Microglia Activation ENSG00000162594 ENSG00000162711 ENSG00000198793 PMC5959746__F3 The biology and therapeutic management of melanoma brain metastases ENSG00000108691 PMC7492550__F1 Identified mechanisms of molecular resistance to anti-TNF therapy in IBD patients ENSG00000162594 ENSG00000099985 ENSG00000170458 ENSG00000168685 PMC8483971__F1 Ethnic Differences in Iron Status ENSG00000010704 ENSG00000106327 ENSG00000105697 PMC7780046__F3 Nuclear factor kappa B (NF‐KB) signaling by N‐myc downstream‐regulated gene 2 (NDRG2)/protein phosphatase 2A (PP2A) complex ENSG00000104856 ENSG00000173039 ENSG00000111321 ENSG00000165795 PMC7780046__F5 Enhancement of epithelial‐to‐mesenchymal transition (EMT) via the loss of N‐myc downstream‐regulated gene 2 (NDRG2) activity ENSG00000170558 ENSG00000165795 PMC10780299__F4 Activation of the NFKB/MAPK signaling pathway by saponins regulates the expression of a series of immune-related cytokines, NO, surface-stimulating factors, and mRNAs and/or proteins of the cell cycle ENSG00000172936 PMC10780299__F3 Saponins activate the TLRs signaling pathway through TLRs, upregulate class I and II MHC molecules in APCs, and promote antigen capture, processing, and presentation ENSG00000134982 PMC8414384__F2 Hypoxia in inhibiting dendritic cells by VEGF signaling in tumor microenvironments: mechanism and application ENSG00000172936 ENSG00000112715 ENSG00000150630 PMC6433121__F4 Proteins that Are Rhythmic in the Pentose-Phosphate Pathway Peak in Anti-phase to Those in Glycolysis ENSG00000142227 ENSG00000108515 PMC7936245__F4 Possible proximal tubule epithelial cell signals in glomerulonephritis and renal cell carcinoma ENSG00000111012 ENSG00000118972 ENSG00000152266 ENSG00000162711 ENSG00000108691 ENSG00000019186 ENSG00000040275 ENSG00000096717 ENSG00000168610 PMC5594548__F7 RNAi amplification, spreading and transcriptional gene silencing pathways ENSG00000198952 ENSG00000184517 ENSG00000070366 PMC6812026__F2 Important metabolism-related cellular signaling cascades where FKBP51 was shown to play a decisive role (see main text for further details) ENSG00000169047 PMC11657595__F2 Mechanisms of GDF15 expression, maturation and secretion ENSG00000128272 ENSG00000162772 ENSG00000130513 ENSG00000079999 PMC7344784__F5 Activation of ATM signaling predicted by IPA-based pathway analysis ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000123374 PMC8072021__F3 Cellular Prion Protein—ROCK Connection: Contribution to Neuronal Homeostasis and Neurodegenerative Diseases ENSG00000142192 ENSG00000105656 PMC8883485__F2 FoxO transcription factors regulate mitochondrial biogenesis ENSG00000126088 ENSG00000100243 ENSG00000096717 ENSG00000106459 PMC5743386__F9 Proposed model shows that MTH-3 induces G2/M phase arrest, autophagy and apoptotic cell death (death receptor/mitochondrial pathways and ER stress) in human breast adenocarcinoma MDA-MB-231 cells ENSG00000134057 ENSG00000087250 ENSG00000168040 ENSG00000145782 ENSG00000057663 PMC9465411__F5 Recent advances on development of p21-activated kinase 4 inhibitors as anti-tumor agents ENSG00000168036 ENSG00000162692 ENSG00000130669 PMC5787447__F5 Current research on head and neck cancer-associated long noncoding RNAs ENSG00000163251 ENSG00000168036 ENSG00000112715 PMC5787447__F3 Current research on head and neck cancer-associated long noncoding RNAs ENSG00000168283 ENSG00000140575 ENSG00000168036 ENSG00000165409 ENSG00000124762 PMC5787447__F2 Current research on head and neck cancer-associated long noncoding RNAs ENSG00000135446 ENSG00000105810 PMC7854724__F6 TGFB signalling acts as a molecular brake of myoblast fusion PMC9305853__F4 Global analysis of differential gene expression within the porcine conceptus transcriptome as it transitions through spherical, ovoid, and tubular morphologies during the initiation of elongation ENSG00000066468 ENSG00000070193 ENSG00000107562 ENSG00000111537 ENSG00000105329 ENSG00000125538 ENSG00000140285 ENSG00000140443 PMC5372786__F1 Pathway for synthesis of ceramide, sphingomyelin, and sphingosine-1 phosphate ENSG00000170989 ENSG00000180739 ENSG00000213694 ENSG00000125910 ENSG00000267534 PMC6025071__F1 IDH pathway and targets in acute leukemia ENSG00000171791 PMC6537282__F1 New biologics and small molecules in inflammatory bowel disease: an update PMC5381705__F4 Target genes of Tongcheng/Landrace specific DEmiRNAs' KEGG pathways enrichment analysis (a) Landrace specific DEmiRNAs target genes enriched in cell cycle pathway ENSG00000132906 ENSG00000002330 ENSG00000108055 ENSG00000102871 ENSG00000277273 ENSG00000168040 ENSG00000164305 ENSG00000276876 ENSG00000135446 ENSG00000132646 ENSG00000123374 ENSG00000164754 ENSG00000026103 PMC8267408__F1 Chemistry-Assisted Proteomic Profiling of O-GlcNAcylation ENSG00000147162 ENSG00000198408 ENSG00000156958 ENSG00000124357 ENSG00000013375 PMC7438479__F8 Pathway that Tisp40 regulates Ischemia-reperfusion induced pyroptosis in kidney ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC10779351__F5 Illustration of Ferroptosis in Pancreatic Beta Cells and Its Relation to NADPH ENSG00000167468 ENSG00000115419 PMC10779351__F4 Illustration of Insulin Signaling and Resistance Pathways ENSG00000169047 ENSG00000198793 ENSG00000127191 PMC10779351__F3 NADPH in Insulin Secretion from Pancreatic Beta-Cells ENSG00000079387 ENSG00000070444 PMC7247689__F2 Mitochondrial homeostasis is based on the balanced interplay between biogenesis and mitophagy ENSG00000198793 ENSG00000158828 ENSG00000106459 PMC10779351__F2 NADPH Production Pathways in Cells ENSG00000151376 ENSG00000070444 ENSG00000065833 ENSG00000065911 ENSG00000100714 PMC9035791__F1 Th17 Pathway in Vascular Inflammation: Culprit or Consort? ENSG00000150782 ENSG00000111537 ENSG00000049768 ENSG00000163702 PMC4066870__F4 Smoke mediates EGFR/Src-dependent and independent cell migration ENSG00000106683 ENSG00000291971 ENSG00000146648 PMC9130572__F2 Pyroptosis: Role and Mechanisms in Cardiovascular Disease ENSG00000278718 ENSG00000162711 ENSG00000189403 PMC8059808__F2 Boolean module is a dynamic module including Snf1, PKA, and TOR pathway as well as crosstalk between them ENSG00000112977 ENSG00000151657 ENSG00000188404 PMC4959097__F1 Cholesterol biosynthetic pathway ENSG00000067064 ENSG00000110921 ENSG00000113161 ENSG00000167508 ENSG00000148377 PMC9035791__F4 Th17 Pathway in Vascular Inflammation: Culprit or Consort? ENSG00000150782 ENSG00000049768 PMC5045062__F2 Prolyl hydroxylase domain enzymes: important regulators of cancer metabolism ENSG00000104812 ENSG00000131473 ENSG00000042832 ENSG00000092621 ENSG00000100412 ENSG00000159399 PMC7780046__F1 N‐myc downstream‐regulated gene 2 (NDRG2) is a key regulator of cellular stress responses ENSG00000165795 PMC6627250__F1 Neoplastic transformation of melanocyte ENSG00000101751 ENSG00000157764 ENSG00000214513 ENSG00000196549 ENSG00000113140 ENSG00000164362 ENSG00000168610 ENSG00000109670 PMC7845582__F2 Vaccine Therapies for Cancer: Then and Now ENSG00000232326 PMC7677583__F1 JAK inhibition and immune regulation by the JAK pathway ENSG00000162594 ENSG00000112964 ENSG00000105397 ENSG00000103522 ENSG00000187266 ENSG00000105639 ENSG00000113494 ENSG00000168685 PMC3964483__F1 Outside the Box Signaling: Secreted Factors Modulate GnRH Receptor-Mediated Gonadotropin Regulation ENSG00000109163 ENSG00000168066 ENSG00000291971 ENSG00000177606 PMC11944057__F2 Crosstalk between the PI3K/AKT/mTOR pathway and the MAPK pathway ENSG00000169047 ENSG00000198793 PMC4216797__F3 Mechanism and Role of AMPK activation ENSG00000177169 ENSG00000110931 PMC10981134__F1 Main alterations in TCR signaling pathway and accessory molecules associated with autoimmunity/immunodeficiency ENSG00000213658 ENSG00000173757 ENSG00000113263 ENSG00000049768 PMC9500666__F8 Non-Esterified Fatty Acid Induces ER Stress-Mediated Apoptosis via ROS/MAPK Signaling Pathway in Bovine Mammary Epithelial Cells ENSG00000128272 ENSG00000171791 PMC4528105__F1 A Protein in the Hippo Signaling Pathway Serves as a Point of Cross-talk to the mTOR Signaling Pathway♦ ENSG00000198793 ENSG00000164327 ENSG00000150457 ENSG00000114019 ENSG00000131023 PMC8040477__F4 Epidermal growth factor receptor (EGFR) signaling pathway and potential mechanism of resistance to cetuximab and panitumumab ENSG00000167601 ENSG00000019991 ENSG00000142627 ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000198793 ENSG00000100985 ENSG00000146648 PMC8949405__F2 MicroRNA-mRNA Regulatory Network Mediates Activation of mTOR and VEGF Signaling in African American Prostate Cancer ENSG00000132906 ENSG00000162889 ENSG00000002330 ENSG00000070831 ENSG00000291971 ENSG00000089159 PMC8949405__F1 MicroRNA-mRNA Regulatory Network Mediates Activation of mTOR and VEGF Signaling in African American Prostate Cancer ENSG00000168209 ENSG00000157764 ENSG00000115457 ENSG00000266173 ENSG00000198793 ENSG00000169047 ENSG00000164327 ENSG00000121879 PMC5362437__F5 Transcriptional suppression of microRNA-27a contributes to laryngeal cancer differentiation via GSK-3Beta-involved Wnt/Beta-catenin pathway ENSG00000138795 ENSG00000168036 PMC8652015__F4 Molecular mechanism of chronic stress affecting the occurrence and development of breast cancer and potential drug therapy ENSG00000101188 ENSG00000140443 PMC6606008__F4 Hippo Pathway for tumor suppression ENSG00000144560 ENSG00000150457 ENSG00000131023 PMC6606008__F3 Wnt signaling pathway with and without ligand binding and APC mutations ENSG00000134982 PMC6606008__F2 Process of Hedgehog pathway begins on binding of specific ligands such as exo-secretion ligand Shh bind to the trans-membrane receptor PATCHED1 (PTCH1) it initiates the HH-GLI pathway ENSG00000141480 ENSG00000128602 PMC4283829__F9 Key role of transient receptor potential melastatin-2 channels in amyloid-Beta-induced neurovascular dysfunction ENSG00000135218 ENSG00000227345 PMC8237272__F6 LGR5 enhances the osteoblastic differentiation of MC3T3-E1 cells through the Wnt/Beta-catenin pathway ENSG00000134982 ENSG00000168036 PMC3417440__F1 Cell death regulation: Signalling pathways and potential sites for pharmacological intervention ENSG00000002330 ENSG00000102871 ENSG00000291971 ENSG00000198793 ENSG00000168036 ENSG00000171791 ENSG00000168040 ENSG00000127191 ENSG00000168610 ENSG00000135446 ENSG00000148798 ENSG00000163914 ENSG00000120868 ENSG00000026103 PMC10095594__F1 Canonical Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3889573__F2 Ras, cAMP/PKA, and MSIL signaling pathways in C ENSG00000188895 ENSG00000070831 ENSG00000177464 ENSG00000135097 PMC3889573__F1 HOG signaling pathway in C ENSG00000123268 PMC3889573__F3 Ca2+/calcineurin, Rim101, and Pkc1/Mpk1 MAPK signaling pathways in C ENSG00000185591 PMC11530815__F3 Medicinal plants as a potential resource for the discovery of novel structures towards cancer drug resistance treatment ENSG00000168040 PMC11530815__F2 Medicinal plants as a potential resource for the discovery of novel structures towards cancer drug resistance treatment ENSG00000002330 ENSG00000198793 PMC8601278__F3 Bioinformatics analyses of the pathogenesis and new biomarkers of chronic obstructive pulmonary disease ENSG00000160185 ENSG00000122224 ENSG00000185808 ENSG00000171791 ENSG00000069667 ENSG00000111796 ENSG00000213658 ENSG00000153283 ENSG00000136997 ENSG00000112699 ENSG00000284764 ENSG00000213809 ENSG00000138795 ENSG00000182568 ENSG00000125651 ENSG00000141576 ENSG00000116157 ENSG00000255072 ENSG00000152464 ENSG00000291502 ENSG00000100575 ENSG00000169288 ENSG00000206190 ENSG00000102245 ENSG00000107485 ENSG00000163634 ENSG00000125245 ENSG00000198612 ENSG00000175792 ENSG00000168685 ENSG00000124784 ENSG00000291603 ENSG00000127452 ENSG00000139187 ENSG00000229314 ENSG00000104980 ENSG00000288185 ENSG00000113263 ENSG00000101425 ENSG00000261701 ENSG00000108559 ENSG00000110448 ENSG00000276463 ENSG00000173726 ENSG00000182162 ENSG00000165795 ENSG00000166428 ENSG00000021300 ENSG00000117091 ENSG00000147454 ENSG00000055163 ENSG00000285318 ENSG00000126353 ENSG00000005381 PMC10535809__F2 Host and HBV Interactions and Their Potential Impact on Clinical Outcomes ENSG00000026103 PMC7176436__F1 De novo and salvage pathways of purine synthesis in eukaryotic cells ENSG00000137198 ENSG00000198931 PMC8233740__F1 Using Diatom and Apicomplexan Models to Study the Heme Pathway of Chromera velia ENSG00000100473 ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000188690 PMC2745384__F6 RCAN1 mediated regulation of cell proliferation and apoptosis: Schematic shows that GC-dependent GR activation and subsequent MAP kinase-dependent phosphorylation enables GR binding to GRE sequences on target genes ENSG00000159200 ENSG00000145321 ENSG00000117602 PMC8000936__F4 DDX11-mediated regulation of EZH2-p21 and PI3K/AKT/mTOR signaling pathways in HCC cells ENSG00000198793 PMC3921546__F1 Representation of epidermal growth factor receptor pathway in response to therapy with anti-epidermal growth factor receptor inhibitors in wild-type and mutant patients ENSG00000157764 ENSG00000198793 ENSG00000146648 PMC8289577__F1 Hair Cell Protection from Ototoxic Drugs PMC5599913__F1 The SMC1 participating in DNA damage repair signaling pathway ENSG00000149311 ENSG00000012048 ENSG00000070950 PMC8876688__F1 Potential of Nrf2 Activation as a Therapeutic Target in Systemic Lupus Erythematosus ENSG00000131473 ENSG00000065911 ENSG00000125538 ENSG00000066739 ENSG00000169710 ENSG00000271303 ENSG00000023909 ENSG00000057663 PMC12220111__F1 Modular engineering design for the compartmentalized synthesis of taxifolin in the peroxisomes of S ENSG00000108849 ENSG00000083857 ENSG00000122966 PMC2593565__F3 Epithelial barrier function by lactobacilli ENSG00000226275 ENSG00000172936 ENSG00000146648 PMC3442422__F1 The Sre1 regulatory pathway ENSG00000157554 ENSG00000159459 PMC7037748__F2 Regulation of the Wnt/Beta-catenin signaling pathway when it is inactive (OFF) and when it is active (ON) ENSG00000154856 ENSG00000281324 ENSG00000162337 ENSG00000167941 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC8131840__F2 Complexity of the Tumor Microenvironment and Its Role in Acute Lymphoblastic Leukemia: Implications for Therapies ENSG00000115415 ENSG00000105639 ENSG00000168610 PMC7037748__F1 Wnt/Beta-catenin signaling pathway, which is inactive in the absence of Wnt ligands (OFF) and active upon binding of Wnt ligands (ON) ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000100744 PMC6448643__F1 Illustration showing the activation of a T lymphocyte (via a three‐signal pathway) by an antigen‐presenting cell ENSG00000198793 ENSG00000105639 PMC6700246__F1 Sphingolipid metabolic pathway ENSG00000139624 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000173599 ENSG00000143418 PMC3542528__F4 Protein network analysis of hits reveals multiple connections between signaling molecules and Golgi proteins ENSG00000167601 ENSG00000114670 ENSG00000130957 ENSG00000152661 ENSG00000178999 ENSG00000077044 ENSG00000108443 ENSG00000007047 ENSG00000102010 ENSG00000169967 ENSG00000122025 ENSG00000183943 ENSG00000079950 ENSG00000184432 ENSG00000158050 ENSG00000115216 ENSG00000087095 ENSG00000117228 ENSG00000065361 ENSG00000110048 ENSG00000149091 ENSG00000159899 ENSG00000043462 ENSG00000105053 ENSG00000132639 ENSG00000096063 ENSG00000066468 ENSG00000284816 ENSG00000169245 ENSG00000133275 ENSG00000117650 ENSG00000138769 ENSG00000140057 ENSG00000060656 ENSG00000034713 ENSG00000112984 ENSG00000135605 ENSG00000173230 ENSG00000135250 ENSG00000185189 PMC9053805__F5 In silico identification of novel biomarkers for key players in transition from normal colon tissue to adenomatous polyps ENSG00000179344 ENSG00000170458 ENSG00000081237 ENSG00000156738 ENSG00000104894 ENSG00000026751 ENSG00000110324 ENSG00000136235 ENSG00000168610 PMC9053805__F4 In silico identification of novel biomarkers for key players in transition from normal colon tissue to adenomatous polyps ENSG00000139193 ENSG00000107562 ENSG00000145147 ENSG00000048462 ENSG00000146469 ENSG00000124491 ENSG00000163132 ENSG00000157005 ENSG00000168610 ENSG00000105894 ENSG00000180875 ENSG00000022267 ENSG00000171951 ENSG00000125245 PMC4576153__F1 Negative regulators take action at almost all steps of TLR signaling ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000131323 ENSG00000083799 ENSG00000168040 ENSG00000175104 ENSG00000276561 PMC3542528__F5 Various subnetworks of signaling molecules that regulate Golgi structure ENSG00000101367 ENSG00000149930 ENSG00000130294 ENSG00000122218 ENSG00000168067 ENSG00000151693 ENSG00000121879 ENSG00000164305 ENSG00000196586 ENSG00000182541 ENSG00000149269 ENSG00000143398 ENSG00000158050 ENSG00000087095 ENSG00000101109 ENSG00000291431 ENSG00000110048 ENSG00000149091 ENSG00000067900 ENSG00000153317 ENSG00000127191 ENSG00000221823 ENSG00000066468 ENSG00000114745 ENSG00000134853 ENSG00000197879 ENSG00000074054 PMC8905735__F9 Ameliorating role of microRNA-378 carried by umbilical cord mesenchymal stem cells-released extracellular vesicles in mesangial proliferative glomerulonephritis PMC4597147__F4 Regulated protein networks in GM-BMMs versus M-BMMs ENSG00000196975 ENSG00000169710 ENSG00000196743 ENSG00000077514 ENSG00000035928 ENSG00000198056 ENSG00000177455 ENSG00000213658 ENSG00000066044 ENSG00000089685 ENSG00000163914 ENSG00000150907 ENSG00000136997 ENSG00000138768 ENSG00000076641 ENSG00000140464 ENSG00000109670 ENSG00000087095 ENSG00000112964 ENSG00000067057 ENSG00000131747 ENSG00000108510 ENSG00000007171 ENSG00000160752 ENSG00000110395 ENSG00000154217 ENSG00000003989 ENSG00000167468 ENSG00000132646 ENSG00000171855 ENSG00000128016 ENSG00000135218 ENSG00000291603 ENSG00000112972 ENSG00000070831 ENSG00000288174 ENSG00000168036 ENSG00000167508 ENSG00000179295 ENSG00000074800 ENSG00000150991 ENSG00000181019 ENSG00000162521 ENSG00000079950 ENSG00000100504 ENSG00000132535 ENSG00000081041 ENSG00000116044 ENSG00000197838 ENSG00000156738 ENSG00000153574 ENSG00000168610 ENSG00000137841 ENSG00000079999 ENSG00000149311 ENSG00000019582 ENSG00000067064 ENSG00000128272 ENSG00000147614 ENSG00000010810 ENSG00000167325 ENSG00000187288 ENSG00000134324 ENSG00000106624 ENSG00000198911 PMC7081333__F8 Piscidin-1 anticancer signaling pathway ENSG00000116688 ENSG00000171109 ENSG00000214253 PMC6260860__F3 Different gene expression profiles in metabolic pathways of E ENSG00000175054 ENSG00000197713 ENSG00000173599 ENSG00000150787 ENSG00000062485 PMC4819695__F1 MYC: regulator of post‐transcriptional mechanisms ENSG00000101751 ENSG00000115524 ENSG00000106245 ENSG00000136997 ENSG00000166169 ENSG00000280548 PMC7250912__F1 Smoking, alcohol consumption and colorectal cancer risk by molecular pathological subtypes and pathways ENSG00000157764 PMC7038207__F2 Connexin hemichannels in mechanotransduction of osteocytes ENSG00000167941 ENSG00000163914 ENSG00000168036 PMC3828201__F1 ERK and PI3K signaling networks are shown, with illustrations of feedback loops and cross talk ENSG00000169047 PMC8652015__F2 Molecular mechanism of chronic stress affecting the occurrence and development of breast cancer and potential drug therapy ENSG00000108691 ENSG00000198793 ENSG00000136997 ENSG00000048028 ENSG00000121807 ENSG00000168610 PMC4816099__F2 Controlling a variety of extracellular and intracellular processes via the phospholipid code ENSG00000102871 PMC1866250__F7 Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance ENSG00000042832 ENSG00000285482 PMC7892797__F1 All detected PLA2/COX pathway genes and regulatory factors and alterations in their transcription levels between patients with schizophrenia and healthy controls ENSG00000183134 ENSG00000160013 ENSG00000125384 ENSG00000168229 ENSG00000124212 ENSG00000160951 PMC6390002__F2 Comparative analysis of genes in regeneration-related signaling pathways of regenerative animals ENSG00000071564 ENSG00000134982 ENSG00000156574 ENSG00000168036 ENSG00000135111 ENSG00000128342 ENSG00000150457 ENSG00000128602 ENSG00000168610 ENSG00000131023 PMC6032276__F6 Differential regulation of skin barrier proteins by Rhodiola crenulata root extract ENSG00000163207 ENSG00000172818 ENSG00000140465 ENSG00000143631 ENSG00000106546 PMC4665079__F6 Autophagic signaling pathway ENSG00000177169 ENSG00000152348 ENSG00000144848 ENSG00000005893 ENSG00000099940 ENSG00000171791 ENSG00000145782 ENSG00000118640 ENSG00000057663 ENSG00000136874 PMC4132373__F1 A healthy neuromuscular junction (NMJ) is a tripartite synapse composed of a motor neuron (MN) terminal synapsing onto a muscle fiber ENSG00000142192 ENSG00000116106 ENSG00000026508 ENSG00000075213 PMC4665079__F4 Death receptor signaling pathway ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC9488186__F1 Promise of mTOR as a therapeutic target pathway in idiopathic pulmonary fibrosis ENSG00000177169 ENSG00000118515 ENSG00000155792 PMC9274113__F2 Functional Regulation of KATP Channels and Mutant Insight Into Clinical Therapeutic Strategies in Cardiovascular Diseases ENSG00000080823 ENSG00000105205 PMC4665079__F2 Mitochondrial apoptotic pathway ENSG00000120868 ENSG00000115317 PMC6829479__F1 Effect of pharmacological and transcriptional inhibition of lysine-specific demethylase 1 (LSD1) on induction of the cell cycle and DNA damage response (DDR) pathway in microvascular endothelial cells (HMEC-1) ENSG00000164053 ENSG00000132646 PMC8278111__F1 Complex role of Wnt ligands in type 2 diabetes mellitus and related complications ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000291971 ENSG00000134982 ENSG00000168036 PMC9169354__F2 Circular RNAs modulate Hippo-YAP signaling: functional mechanisms in cancer ENSG00000126016 ENSG00000109321 ENSG00000136997 ENSG00000139926 ENSG00000131023 ENSG00000125968 PMC9169354__F1 Circular RNAs modulate Hippo-YAP signaling: functional mechanisms in cancer ENSG00000186575 ENSG00000144560 ENSG00000150457 ENSG00000131023 PMC8151045__F1 PD-1 and LAG-3 Checkpoint Blockade: Potential Avenues for Therapy in B-Cell Lymphoma PMC1929113__F6 Upregulation of cyclins and CDKs in melanoma cells ENSG00000145604 ENSG00000149311 ENSG00000175054 ENSG00000123374 PMC3179938__F3 Top IPA generated network ENSG00000108839 ENSG00000161905 ENSG00000111796 ENSG00000239998 ENSG00000083535 ENSG00000237693 ENSG00000180008 PMC6444272__F2 Herb-compound-target-signaling pathway network of BSJPD ENSG00000112715 PMC5959770__F2 Perspectives on Glycosylation and its Congenital Disorders ENSG00000162377 ENSG00000244038 ENSG00000089597 PMC8437140__F2 H19 in liver injury and fibrosis ENSG00000108691 ENSG00000011304 ENSG00000119888 ENSG00000171791 PMC6873994__F4 Predicted potential targets to combine with MAPK/ERK inhibition, using graph analytics ENSG00000198901 ENSG00000213658 ENSG00000163914 ENSG00000168002 ENSG00000167965 ENSG00000105568 ENSG00000127948 PMC8437140__F1 The bile acid/FXR pathway by lncRNAs ENSG00000042832 ENSG00000167910 ENSG00000180432 PMC7691682__F8 Some transcripts encoding enzymes involved in the glycosylphosphatidylinositol (GPI)-anchor protein biosynthetic pathway are down-regulated in the CF specific medium (CFSM) culture condition (G condition) ENSG00000275600 ENSG00000142892 ENSG00000143315 ENSG00000108474 ENSG00000135845 ENSG00000100564 ENSG00000136908 ENSG00000197858 ENSG00000197121 ENSG00000241878 PMC8196898__F5 Circulating PTGS2, JAG1, GUCY2C and PGF mRNA in Peripheral Blood and Serum as Potential Biomarkers for Patients with Metastatic Colon Cancer ENSG00000105664 ENSG00000283780 ENSG00000128917 ENSG00000148400 ENSG00000256762 ENSG00000171791 ENSG00000100985 PMC6993871__F6 Simplified schematic of the cholesterol biosynthesis pathway and MARCH6 targets ENSG00000116133 ENSG00000172893 ENSG00000113161 PMC8014339__F7 F528 treatment ameliorated smoke-induced inflammation and emphysema through NFKB signaling pathway ENSG00000087245 ENSG00000100985 PMC10816189__F5 Cell cycle metabolic pathway, with Zhuansihao serving as the control and 071113 as the experimental group ENSG00000118007 ENSG00000108055 ENSG00000134982 ENSG00000091651 ENSG00000277273 ENSG00000117399 ENSG00000093009 ENSG00000145604 ENSG00000094804 ENSG00000101972 ENSG00000170458 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 PMC10816189__F6 Plant hormone signal transduction pathway, with Zhuansihao serving as the control and 071113 as the experimental group ENSG00000110934 ENSG00000221818 ENSG00000121058 PMC5850959__F6 Transcriptomic data shows immunometabolic effects of vitamin D ENSG00000143252 ENSG00000073578 ENSG00000100412 ENSG00000117118 ENSG00000163541 ENSG00000105953 ENSG00000172340 ENSG00000146701 ENSG00000091140 ENSG00000101365 ENSG00000062485 PMC3350847__F2 Canonical Wnt pathway ENSG00000134982 ENSG00000168036 PMC5563989__F2 The apoptosis regulatory network under ER stress ENSG00000128272 ENSG00000144895 PMC11586091__F1 JAK/STAT3 signaling pathway regulated by circRNAs ENSG00000087095 ENSG00000108691 ENSG00000168610 PMC6398012__F6 Proposed mechanism by which type 2 diabetes (T2DM) and aerobic exercise can affect the brain and lead to alterations of hippocampal glucose metabolism with subsequent effects on synaptic plasticity-associated proteins ENSG00000162711 ENSG00000198793 ENSG00000096717 PMC6027299__F2 Global view and function analysis of the ceRNA network in GC ENSG00000111581 ENSG00000151725 ENSG00000065911 ENSG00000281324 ENSG00000092853 ENSG00000163739 ENSG00000131747 ENSG00000072274 ENSG00000123485 ENSG00000291964 ENSG00000160949 ENSG00000123219 ENSG00000145604 ENSG00000127586 ENSG00000137807 ENSG00000275568 ENSG00000143476 ENSG00000132646 ENSG00000120685 ENSG00000171848 ENSG00000133657 ENSG00000112742 ENSG00000080839 ENSG00000253729 PMC11586091__F3 Function of exosomal circRNAs in tumorigenesis ENSG00000182718 ENSG00000138639 ENSG00000005882 ENSG00000171634 ENSG00000198793 ENSG00000128052 ENSG00000170348 ENSG00000282899 ENSG00000149480 PMC4968756__F7 Model for p53-mediated resolution of replication barriers ENSG00000101751 ENSG00000070950 ENSG00000121988 PMC6492315__F4 Schematic overview for the roles of miR-24, miR-23a and miR-145 in TGFB signaling in AKI ENSG00000185591 ENSG00000120868 ENSG00000122194 ENSG00000064012 ENSG00000164305 PMC8315560__F1 Cancer stem cells, epithelial-mesenchymal transition, ATP and their roles in drug resistance in cancer ENSG00000168036 ENSG00000167701 PMC8181757__F6 CHOP Regulates Endoplasmic Reticulum Stress-Mediated Hepatoxicity Induced by Monocrotaline ENSG00000128272 ENSG00000144895 PMC3328674__F1 Exercise-stimulated glucose uptake in skeletal muscle ENSG00000198793 ENSG00000132170 ENSG00000106459 ENSG00000165264 PMC3098671__F2 Endoplasmic-Reticulum Calcium Depletion and Disease ENSG00000128272 ENSG00000187446 ENSG00000144895 ENSG00000100219 PMC5545609__F1 Normal endothelial cell metabolismA schematic of the principal pathways in healthy EC metabolism and the rate-limiting enzymes, carriers, and transporters (shown in blue) ENSG00000180210 ENSG00000115419 ENSG00000026103 PMC8085551__F6 Transcriptomic and Metabolomic Profiling Reveals the Protective Effect of Acanthopanax senticosus (Rupr. & Maxim.) Harms Combined With Gastrodia elata Blume on Cerebral Ischemia-Reperfusion Injury ENSG00000158104 ENSG00000171759 ENSG00000172113 ENSG00000188611 ENSG00000099810 ENSG00000167900 ENSG00000168350 PMC4654537__F6 Characterization of FGF23-Dependent Egr-1 Cistrome in the Mouse Renal Proximal Tubule ENSG00000164237 ENSG00000130475 ENSG00000173611 ENSG00000283946 ENSG00000099864 ENSG00000125656 PMC5545609__F4 Diabetic endothelial cell metabolismIn diabetic ECs, hyperglycemia increases production of ROS through a variety of intracellular sources, including NADPH oxidase, xanthine oxidase, uncoupled eNOS, and impaired pentose phosphate pathway (PPP) ENSG00000143799 ENSG00000180210 ENSG00000117525 PMC5005329__F1 Current view on T cell NNCS in regulation of immune function ENSG00000291603 ENSG00000167323 ENSG00000134982 ENSG00000293604 PMC5053480__F5 Proteomic Analysis Implicates Dominant Alterations of RNA Metabolism and the Proteasome Pathway in the Cellular Response to Carbon-Ion Irradiation ENSG00000168530 ENSG00000105664 ENSG00000133110 ENSG00000111799 ENSG00000117601 ENSG00000108821 ENSG00000274665 PMC8268101__F2 Molecular Characteristics of RAGE and Advances in Small-Molecule Inhibitors ENSG00000070831 ENSG00000168610 PMC5053480__F4 Proteomic Analysis Implicates Dominant Alterations of RNA Metabolism and the Proteasome Pathway in the Cellular Response to Carbon-Ion Irradiation ENSG00000168530 ENSG00000183011 ENSG00000198931 ENSG00000132485 ENSG00000274665 ENSG00000153140 ENSG00000105664 ENSG00000133110 ENSG00000111799 ENSG00000136527 ENSG00000099810 ENSG00000198125 ENSG00000108821 ENSG00000146701 PMC6787681__F4 AT-rich interactive domain 1A (ARID1A) chromatin remodeling abnormalities in ovarian clear cell carcinoma (OCCC) ENSG00000117713 ENSG00000198793 ENSG00000136997 ENSG00000124762 PMC9144171__F3 Endocardial Regulation of Cardiac Development ENSG00000175206 ENSG00000135547 ENSG00000148400 ENSG00000120149 ENSG00000135111 ENSG00000163132 ENSG00000164532 ENSG00000112715 ENSG00000163217 ENSG00000170961 ENSG00000121068 ENSG00000133110 ENSG00000038427 ENSG00000122691 ENSG00000164107 ENSG00000178568 PMC6192708__F2 Biomedical Informatics on the Cloud: A Treasure Hunt for Advancing Cardiovascular Medicine ENSG00000142192 ENSG00000141753 PMC8517477__F2 STING Signaling and Sterile Inflammation ENSG00000169245 ENSG00000164430 ENSG00000189403 PMC8517477__F1 STING Signaling and Sterile Inflammation ENSG00000183735 ENSG00000164430 PMC8393318__F8A Gastroprotection against Rat Ulcers by Nephthea Sterol Derivative ENSG00000175634 ENSG00000002330 ENSG00000198793 ENSG00000213341 PMC10522995__F1 CREB-Regulated Transcriptional Coactivator 2 Proteome Landscape is Modulated by SREBF1 ENSG00000160741 PMC10376827__F1 Dissecting the Protective Effect of CD8+ T Cells in Response to SARS-CoV-2 mRNA Vaccination and the Potential Link with Lymph Node CD8+ T Cells ENSG00000111537 ENSG00000134982 ENSG00000026103 PMC7283386__F2 Signaling pathways in wear debris-activated osteoblasts ENSG00000168036 ENSG00000171791 PMC7855700__F1 Main IDO1 and ARG1-mediated pathways that regulate autoimmunity, cytotoxicity, and neuroprotection ENSG00000291971 ENSG00000118520 ENSG00000106546 PMC4905428__F1 Regulation of Smad4 by the FGF/MAPK and Wnt signaling pathways ENSG00000134982 ENSG00000138798 PMC10935121__F8 DEG pathways involved in the sesquiterpene synthesis pathway ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC8071330__F3 Ovarian cancer stem cell (OCSC)-associated signaling pathways ENSG00000281324 ENSG00000162337 ENSG00000074181 ENSG00000168036 ENSG00000128602 ENSG00000168610 PMC6896163__F2 FOXO1 regulates activation and function of dendritic cells ENSG00000150907 ENSG00000198793 ENSG00000164327 ENSG00000136869 ENSG00000126353 PMC4237178__F4 Canonical and non-canonical Wnt pathways exert opposite effects on the formation of the vertebrate NMJ ENSG00000107404 ENSG00000134569 ENSG00000030304 ENSG00000163914 ENSG00000168036 PMC11781520__F1 MiR-29s in the signalling of innate immunity ENSG00000108691 ENSG00000213928 ENSG00000167207 ENSG00000105397 ENSG00000115415 ENSG00000187554 ENSG00000172936 PMC6382076__F1 Trichuris suis soluble products induce Rab7b expression and limit TLR4 responses in human dendritic cells ENSG00000213928 ENSG00000167207 ENSG00000102871 ENSG00000183486 ENSG00000162772 ENSG00000087077 ENSG00000142166 ENSG00000114738 ENSG00000183735 ENSG00000136997 ENSG00000276051 ENSG00000164400 ENSG00000136869 ENSG00000125148 ENSG00000140968 ENSG00000173039 ENSG00000168040 ENSG00000108691 ENSG00000224320 ENSG00000105397 ENSG00000115415 ENSG00000185201 ENSG00000172005 ENSG00000135114 ENSG00000134070 ENSG00000142089 ENSG00000172936 ENSG00000131323 ENSG00000100985 ENSG00000175104 ENSG00000184216 PMC8583789__F7 RIF1 Links Replication Timing with Fork Reactivation and DNA Double-Strand Break Repair ENSG00000012048 ENSG00000080345 ENSG00000171984 ENSG00000122376 ENSG00000034533 PMC2945950__F5 Moral graph Dm obtained from BCR pathway ENSG00000177455 ENSG00000095585 ENSG00000110651 ENSG00000197943 ENSG00000152689 ENSG00000010671 PMC4275311__F3 Cellular and metabolic functions for autophagy in cancer cells ENSG00000198793 ENSG00000175104 ENSG00000079999 PMC10750294__F8 MANF Promotes Unexplained Recurrent Miscarriages by Interacting with NPM1 and Downregulating Trophoblast Cell Migration and Invasion ENSG00000087245 ENSG00000181163 ENSG00000132646 ENSG00000100985 PMC2945950__F6 Triangulated graph Dt obtained from BCR pathway ENSG00000177455 ENSG00000095585 ENSG00000110651 ENSG00000197943 ENSG00000152689 ENSG00000010671 PMC4275311__F1 Cellular and metabolic functions for autophagy in cancer cells ENSG00000177169 ENSG00000128272 ENSG00000157764 ENSG00000144895 ENSG00000136997 ENSG00000057663 PMC2945950__F1 BCR signaling pathway ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000010671 ENSG00000152430 PMC8092109__F9 Cinnamaldehyde inhibits the growth of Phytophthora capsici through disturbing metabolic homoeostasis ENSG00000171444 ENSG00000128928 ENSG00000084774 PMC2945950__F2 ERBB signaling pathway ENSG00000169291 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000169752 PMC8525858__F7 Small-molecule Akt-activation in airway cells induces NO production and reduces IL-8 transcription through Nrf-2 ENSG00000181019 ENSG00000187554 ENSG00000079999 PMC6468910__F3 ER stress and chemo-resistance: Role of protein kinase R-like endoplasmic reticulum kinase (PERK) ENSG00000128272 ENSG00000144895 ENSG00000079999 PMC9033823__F6 Oncogenic circuit involving FUS-DDIT3, the IGF-IR/PI3K/AKT pathway, and the Hippo/YAP1 axis in MLS ENSG00000131023 PMC12164393__F2 ICI myocarditis ENSG00000169248 ENSG00000169245 ENSG00000136859 ENSG00000277943 PMC6481335__F4 Heatmap and expression values of probe sets related to irinotecan metabolism in both liver and tumor ENSG00000172828 ENSG00000172831 ENSG00000134982 ENSG00000103222 ENSG00000118777 ENSG00000023839 ENSG00000262243 PMC5713423__F1 Schematic representation of Cyclic GMP-AMP synthase (cGAS)/Stimulator of interferon genes(STING) signaling mediated T cell priming in tumor microenvironment ENSG00000164430 PMC3060045__F2 ErbB receptor signaling and regulation ENSG00000169291 ENSG00000163235 ENSG00000291971 ENSG00000138798 ENSG00000146648 ENSG00000178568 PMC9561988__F1 Targeting the DNA Damage Response and DNA Repair Pathways to Enhance Radiosensitivity in Colorectal Cancer ENSG00000143799 ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000123374 ENSG00000051180 ENSG00000138385 ENSG00000139618 PMC3437743__F1 Glutathione and modulation of cell apoptosis ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC6798812__F11 Cell Therapeutic Strategies for Spinal Cord Injury ENSG00000242689 ENSG00000166278 PMC6651805__F6 Schematic diagram summarizes the mechanism whereby CCN3 promotes Runx2 and osterix expression in osteoblasts ENSG00000136999 PMC9353920__F6 Molecular mechanisms of Biyu decoction as treatment for psoriasis: A network pharmacology and molecular docking study ENSG00000134982 ENSG00000103522 ENSG00000168040 ENSG00000049768 ENSG00000127191 ENSG00000106546 ENSG00000069667 ENSG00000162594 ENSG00000213658 ENSG00000157227 ENSG00000148798 ENSG00000137265 ENSG00000056558 ENSG00000107485 ENSG00000131323 ENSG00000128342 PMC9692260__F3 Anthocyanin in Modulating Diabetic Cardiovascular Disease and Its Potential to Be Developed as a Nutraceutical ENSG00000162692 PMC4581604__F9 Diagram summarizing the Rheb-mTOR signaling pathway and findings presented in this study ENSG00000169047 PMC9692260__F1 Anthocyanin in Modulating Diabetic Cardiovascular Disease and Its Potential to Be Developed as a Nutraceutical ENSG00000162711 ENSG00000120868 ENSG00000162692 PMC2846691__F1 Pathways initiated by ACSL, FATP, and ACSBG isoforms ENSG00000173599 ENSG00000198670 PMC12084380__F5 Therapeutic strategies targeting immunosenescence ENSG00000149311 ENSG00000169710 PMC12084380__F4 Distinct phenotypic and functional alterations in immune system in aged individuals with sepsis compared with young patients ENSG00000162711 ENSG00000163739 ENSG00000116688 ENSG00000136869 ENSG00000168610 PMC12095308__F4 Antiviral type I interferon (IFN) response pathway and known evasion mechanisms of orthohantaviruses ENSG00000213928 ENSG00000276561 ENSG00000142166 ENSG00000183735 ENSG00000239732 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000121060 ENSG00000164342 PMC3111376__F9 Overrepresented miRNA regulatory pathways in PKD PMC9163834__F7 MicroRNA Expression in Circulating Leukocytes and Bioinformatic Analysis of Patients With Moyamoya Disease ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000185269 PMC6469018__F3 Signaling pathway of different DCs receptors (CLRs) ENSG00000187796 PMC12084380__F3 Prematurely aged immune cells during sepsis contribute to immunosuppressive state ENSG00000139193 ENSG00000137033 ENSG00000118242 ENSG00000121966 PMC12084380__F2 Sepsis induces aberrant aging of immune cells which further exacerbates excessive inflammation ENSG00000149311 ENSG00000177575 ENSG00000141867 ENSG00000170458 ENSG00000197632 ENSG00000136869 ENSG00000164305 ENSG00000132693 ENSG00000121966 PMC3943605__F4 GENETICS AND EPIGENETICS OF ADRENOCORTICAL TUMORS ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC11964413__F7 Proposed mechanism suggests that ABCG8 upregulation in RT-R-MDA-MB-231 cells mediates cholesterol efflux, leading to increased cancer cell progression through the LRP6/Wnt/Beta-catenin signaling pathway in RT-R-MDA-MB-231 cells ENSG00000281324 ENSG00000169710 ENSG00000168036 ENSG00000166851 ENSG00000143921 PMC9524158__F1 New insights into the interplay between autophagy and oxidative and endoplasmic reticulum stress in neuronal cell death and survival ENSG00000136997 ENSG00000101557 PMC6474664__F3 Identification of unique pathways after treatment with SC-3–141 ENSG00000117724 ENSG00000198901 ENSG00000147202 ENSG00000134982 ENSG00000140284 ENSG00000161654 ENSG00000291348 ENSG00000064995 PMC9476729__F2 Mongolian medicine in treating type 2 diabetes mellitus combined with nonalcoholic fatty liver disease via FXR/LXR-mediated P2X7R/NLRP3/NFKB pathway activation ENSG00000042832 PMC8278622__F1 Setting the pick: Can PI3K inhibitors circumvent CDK 4/6 inhibitor resistance? ENSG00000135446 ENSG00000105810 ENSG00000139687 PMC6348405__F1 Mitochondria-to-nuclear retrograde signaling pathways in mammals ENSG00000128272 ENSG00000167434 ENSG00000079999 PMC3185527__F3 Illustration of the type I IFN signaling pathway and its inhibition by the henipavirus P, V and W proteins ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC6348405__F3 ATF4 is activated by the perturbation of mitochondrial function ENSG00000006695 ENSG00000128272 ENSG00000105550 ENSG00000116688 ENSG00000285069 ENSG00000171109 PMC6348405__F2 Activation of MRS reconfigures mitochondrial metabolism in yeast ENSG00000170558 ENSG00000011143 PMC6348405__F5 Growth signal activates ATF4 and mitochondrial metabolism ENSG00000128272 ENSG00000144895 PMC6348405__F4 ATF4 regulates the serine synthetic and mitochondrial Folate-mediated 1C metabolism pathway ENSG00000065911 ENSG00000092621 ENSG00000135069 ENSG00000146733 ENSG00000116761 PMC9409897__F5 Enhancing Genome-Scale Model by Integrative Exometabolome and Transcriptome: Unveiling Carbon Assimilation towards Sphingolipid Biosynthetic Capability of Cordyceps militaris ENSG00000039537 ENSG00000042832 PMC6348405__F6 Cooperative gene regulation for mitochondrial quality control by Nrf2 and ATF4 ENSG00000065911 ENSG00000128272 ENSG00000101255 ENSG00000158828 ENSG00000135069 ENSG00000070669 PMC4267896__F3 Central LepRb expression sites and related neuronal circuits ENSG00000198576 ENSG00000115138 ENSG00000260428 PMC7936166__F7 Relationship between AMPK signaling pathway and lipid metabolism in laying hen hepatocytes ENSG00000026103 PMC6798326__F9 TSHR mediated signaling induced OF proliferation through Akt signaling and induction of miR-146a and miR-155 ENSG00000183579 ENSG00000165409 PMC9266727__F1 State-of-the-Art Molecular Oncology of Lung Cancer in Taiwan ENSG00000138449 ENSG00000066926 ENSG00000164362 ENSG00000176153 PMC1965265__F6 A schematic representation of differential testosterone action on morphoregulatory gene expression in the rat VP and LP lobes ENSG00000070193 ENSG00000164690 ENSG00000167034 PMC5530849__F4 KEGG pathway of apoptosis.Notes: The red-colored genes are differentially expressed genes enriched in the pathway in the study ENSG00000159921 ENSG00000102871 ENSG00000127191 ENSG00000135116 ENSG00000084774 ENSG00000026103 PMC6721055__F1 SUMO conjugation/deconjugation cycle ENSG00000142230 ENSG00000116030 ENSG00000188612 ENSG00000177688 ENSG00000184900 ENSG00000062485 PMC9656535__F5 Uncovering the Anticancer Potential of Polydatin: A Mechanistic Insight ENSG00000135446 ENSG00000170558 ENSG00000123374 PMC4703831__F3 Genome-wide association study identifies four novel susceptibility loci underlying inguinal hernia ENSG00000100234 ENSG00000087245 ENSG00000170606 ENSG00000140943 ENSG00000102854 ENSG00000168610 ENSG00000092820 ENSG00000137801 ENSG00000169245 ENSG00000065978 ENSG00000074800 ENSG00000224320 ENSG00000135387 ENSG00000130402 ENSG00000116030 ENSG00000184900 ENSG00000215301 ENSG00000130726 PMC6721055__F3 SUMOylation regulates gene expression during Acute Myeloid Leukemia (AML) response to chemo- and differentiation therapies ENSG00000142230 PMC3604032__F1 PI3K/Akt/mTOR signaling in breast cancer ENSG00000169047 PMC1885837__F6 Obstructive nephropathy: insights from genetically engineered animals ENSG00000122194 PMC9289165__F2 Targeting CD47 as a Novel Immunotherapy for Breast Cancer ENSG00000198053 PMC5391045__F2 Heart Failure in Pediatric Patients with Congenital Heart Disease ENSG00000160789 ENSG00000134755 ENSG00000077522 ENSG00000156574 ENSG00000057294 ENSG00000046604 ENSG00000155657 PMC5710859__F1 Molecular insights into desmoid tumors ENSG00000134982 ENSG00000168036 ENSG00000114315 ENSG00000078098 ENSG00000196628 PMC9234166__F1 Tandem Mass Tagging Based Identification of Proteome Signatures for Reductive Stress Cardiomyopathy ENSG00000042832 ENSG00000171503 ENSG00000073578 ENSG00000119471 ENSG00000156467 ENSG00000111271 ENSG00000131828 ENSG00000158125 ENSG00000166136 ENSG00000181019 ENSG00000145439 ENSG00000167468 ENSG00000189043 ENSG00000130347 ENSG00000137714 ENSG00000122971 ENSG00000275544 PMC7241359__F1 Methotrexate has been recognized by the World Health Organization as an ‘essential medication’, principally due to its broad diversity of mechanisms of action ENSG00000228716 ENSG00000130234 ENSG00000189403 ENSG00000136869 ENSG00000035928 PMC3586519__F1 Schematic illustrating the cancer utilization of the metabolic pathways PMC11808587__F2 The role of mGlu5 activation in neuropathic pain ENSG00000169245 ENSG00000108691 ENSG00000104321 ENSG00000196689 PMC8717973__F4 Conversion of PanAms into CoA antimetabolites ENSG00000138621 ENSG00000127125 PMC4182169__F2 Nutrient-induced cell proliferation in the crypt ENSG00000168283 ENSG00000168036 PMC5102139__F8 Pathway map of NOD-like receptor signaling in independent JU-RME ENSG00000182511 ENSG00000167207 ENSG00000276068 PMC3935732__F4 Role of ABL Family Kinases in Cancer: from Leukemia to Solid Tumors ENSG00000291971 ENSG00000099942 ENSG00000168610 ENSG00000121966 PMC11201989__F8 Working model for PD-L1 in the regulation of ciliogenesis ENSG00000109083 ENSG00000106571 ENSG00000187535 ENSG00000167461 PMC2290973__F2 Pathway Studio diagram of common regulators of differentially expressed genes ENSG00000070831 ENSG00000181104 ENSG00000128052 ENSG00000115904 ENSG00000149294 ENSG00000122194 ENSG00000081189 ENSG00000281857 PMC1140402__F2 The central carbon metabolism of E ENSG00000198408 ENSG00000122966 ENSG00000172005 PMC7050137__F3 Different epigenetic signaling pathways regulated during TGF-Beta-induced EMT ENSG00000169554 ENSG00000180447 ENSG00000143379 ENSG00000074266 ENSG00000132510 ENSG00000008083 PMC6164406__F1 Toll-like receptor (TLR) 4 signaling pathway ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC7464074__F1 HER2 signaling pathway, mechanism of action of targeted therapies, and resistance mechanisms ENSG00000198793 ENSG00000140443 PMC3543090__F8 Model showing the effect of miR-182-5p on the DNA repair pathway ENSG00000012048 ENSG00000276618 ENSG00000067369 ENSG00000123268 ENSG00000183765 PMC2855646__F7 Summary of biosynthetic pathway for O-mannosyl glycans on A dystroglycan in mammals ENSG00000009830 ENSG00000130714 PMC3543090__F4 MicroRNA-182-5p targets a network of genes involved in DNA repair ENSG00000131462 ENSG00000146872 ENSG00000277273 ENSG00000067369 ENSG00000124762 ENSG00000134480 ENSG00000183765 ENSG00000012048 ENSG00000175054 ENSG00000113456 ENSG00000276618 ENSG00000171720 ENSG00000101773 ENSG00000113558 ENSG00000123374 ENSG00000105810 ENSG00000139687 ENSG00000166169 ENSG00000166167 ENSG00000101751 ENSG00000131747 ENSG00000116717 ENSG00000101224 ENSG00000149311 ENSG00000145604 ENSG00000198176 ENSG00000135446 ENSG00000146592 ENSG00000149554 ENSG00000095002 ENSG00000123268 PMC9244687__F2 Prolactin: The Third Hormone in Breast Cancer ENSG00000291971 PMC8399337__F1 Epithelial to Mesenchymal Transition in Patients with Pancreatic Ductal Adenocarcinoma: State-of-the-Art and Therapeutic Opportunities ENSG00000125538 ENSG00000168036 ENSG00000146648 PMC7812236__F1 Notch signalling pathway ENSG00000283780 ENSG00000136997 ENSG00000114315 PMC7528681__F1 WNT Signaling in Lung Repair and Regeneration ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000134982 ENSG00000177606 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC7140873__F2 Analysis of different miRNAs families and their target genes implicated in the regulation of flower induction ENSG00000168374 ENSG00000134287 PMC5040924__F12 Activation of NFKB and STAT signaling pathway ENSG00000111537 ENSG00000170458 ENSG00000115415 ENSG00000125538 PMC11703395__F5 Advanced whole transcriptome sequencing and artificial intelligence/machine learning (AI/ML) in imiquimod-induced psoriasis-like inflammation of human keratinocytes ENSG00000111537 ENSG00000110148 ENSG00000114737 ENSG00000198793 ENSG00000177606 ENSG00000231925 ENSG00000169032 ENSG00000196396 ENSG00000230034 ENSG00000124762 ENSG00000179295 PMC8484301__F4 Novel inactivated whole-cell Pseudomonas aeruginosa vaccine that acts through the cGAS-STING pathway ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000187554 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000136936 PMC6831300__F8 Hypothetic model of signaling pathways involved in the differentiation of hiPSC-CM from mesodermal progenitors ENSG00000134982 ENSG00000168036 PMC6580993__F9 Simplified signaling pathway: this simplified signaling cartoon encompasses all significant molecular changes detected in this study in spleen, hippocampus, and plasma after PEA treatment (PEA/sal) ENSG00000150782 ENSG00000157933 ENSG00000185386 ENSG00000125538 ENSG00000198670 PMC8215363__F2 Reversing Post-Infectious Epigenetic-Mediated Immune Suppression ENSG00000104856 ENSG00000169245 ENSG00000171720 ENSG00000125538 ENSG00000189403 ENSG00000172936 ENSG00000096717 ENSG00000175104 PMC7792133__F3 PI3K-AKT-mTOR inhibitors and CDK4/6 inhibitors orchestrate multiple effects on immune cells in the tumor immune microenvironment ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC5650615__F1 Simplified scheme of innate immune recognition mediated by PRRs ENSG00000162711 ENSG00000167207 ENSG00000163568 ENSG00000125538 ENSG00000172005 ENSG00000136869 ENSG00000091106 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000106100 ENSG00000184216 PMC7557148__F2 Some key events during early embryogenesis in Arabidopsis ENSG00000127445 PMC8235365__F10 Astaxanthin Protects Dendritic Cells from Lipopolysaccharide-Induced Immune Dysfunction ENSG00000136869 PMC5076471__F1 Inositol pyrophosphates and their corresponding bisphosphonate analogues ENSG00000068745 ENSG00000168781 ENSG00000176095 PMC11821611__F4 Biosynthetic pathway of flavor in fresh C ENSG00000105953 ENSG00000062485 PMC5041197__F7 CD95-mediated cell migration occurs through a Bcl-2/BclxL/VDAC1/MCU-driven mitochondrial calcium loading ENSG00000002330 ENSG00000167323 ENSG00000293604 ENSG00000156026 ENSG00000168040 ENSG00000146648 ENSG00000115317 PMC3185727__F1 Illustration of the endogenous RNAi pathway and therapeutic mimics ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC8571891__F1 Oncogenic KRAS in the prognosis, diagnosis and treatment of colorectal cancer ENSG00000198793 ENSG00000146648 PMC2849133__F4 Main targets of RhoA and ROCK, involved in organization of the cytoskeleton ENSG00000131095 ENSG00000182541 PMC11132832__F5 Hub target-pathway network (67 nodes and 95 edges) ENSG00000111537 ENSG00000105329 PMC5286800__F4 Summary of DNA damage-induced breast cancer by estrogen and stressors ENSG00000149311 PMC4339278__F1 Inflammasome activation and cross-talk between endothelial cells (ECs) and macrophages (MØ) in atherogenesis ENSG00000162711 ENSG00000135218 ENSG00000130164 ENSG00000125538 ENSG00000172936 ENSG00000162692 PMC3361414__F5 Schematic representation of the interplay of T7 gp5.5, gp3, E ENSG00000278316 ENSG00000178732 ENSG00000138385 PMC8892214__F2 Effect of Erythropoietin and Its Derivatives on Ischemic Stroke Therapy: A Comprehensive Review ENSG00000102145 ENSG00000084093 ENSG00000186716 ENSG00000198793 ENSG00000187266 ENSG00000096717 ENSG00000106459 PMC6994496__F7 Proposed new pathway that operates upstream of the CRL2VHL complex and involves the UBXN7 cofactor protein and its regulation by mitochondrial MUL1 E3 ligase ENSG00000090432 ENSG00000134086 ENSG00000100387 ENSG00000154582 ENSG00000163960 PMC4452181__F4 Correction: Pathway-Based Analysis of Genome-Wide siRNA Screens Reveals the Regulatory Landscape of App Processing ENSG00000170608 ENSG00000262785 ENSG00000142192 ENSG00000169856 ENSG00000182759 ENSG00000122859 ENSG00000164305 ENSG00000106331 ENSG00000125820 ENSG00000196549 ENSG00000121351 ENSG00000130675 ENSG00000205155 ENSG00000139515 ENSG00000182240 ENSG00000163623 ENSG00000152804 ENSG00000114315 PMC4081668__F2 Nuclear export of hepatitis B virus mRNAs ENSG00000172936 PMC11324288__F1 SLC44A2 mediates the VSMC phenotypic switch in aortic aneurysm ENSG00000259207 ENSG00000159216 ENSG00000136826 PMC4490046__F3 Cell Signaling and Transcription Factors Regulating Cell Fate During Formation of the Mouse Blastocyst ENSG00000165556 ENSG00000141448 ENSG00000107485 PMC7582278__F6 Ingenuity Pathway Analysis (IPA) prediction network of miR-342-3p/-5p and cardiovascular disease ENSG00000124102 ENSG00000269335 ENSG00000150630 PMC8198482__F2 Neurotrophins as Key Regulators of Cell Metabolism: Implications for Cholesterol Homeostasis ENSG00000130164 ENSG00000113161 PMC2808370__F7 Possible mechanism by which Wnt determines the specificity of signalling pathway ENSG00000154342 ENSG00000281324 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC11099600__F4 KEGG Pathway Analysis of ultravist-treated mast cells ENSG00000145604 ENSG00000168003 ENSG00000106070 ENSG00000198793 ENSG00000163914 ENSG00000198517 ENSG00000155792 ENSG00000176641 PMC6853184__F5 Pathway enrichment analysis of primary human lung cell secretory proteins with decreased abundance in response to PC ENSG00000262406 ENSG00000087245 ENSG00000154736 ENSG00000137673 ENSG00000137845 ENSG00000122194 ENSG00000116962 ENSG00000143537 ENSG00000277571 ENSG00000109861 ENSG00000157227 ENSG00000149968 ENSG00000163131 ENSG00000026508 ENSG00000123342 ENSG00000102996 ENSG00000100985 ENSG00000158859 ENSG00000134531 PMC4770149__F1 Developmental pathways are frequently activated in cancer ENSG00000168214 ENSG00000134982 ENSG00000128602 PMC4821826__F4 BCR signaling pathway is the top-ranked network with increasing association with HuR in response to NS3/4A overexpression ENSG00000105369 ENSG00000002330 ENSG00000070831 ENSG00000007312 ENSG00000198793 ENSG00000020633 ENSG00000081189 ENSG00000010671 ENSG00000071564 ENSG00000177455 ENSG00000095585 ENSG00000180353 ENSG00000159216 ENSG00000120899 ENSG00000077420 ENSG00000010810 ENSG00000186716 ENSG00000177606 ENSG00000150907 ENSG00000102935 ENSG00000198286 PMC6683584__F8 The mechanism of Notch1 signaling and CXCL12/CXCR4 axis in GICs self-renewal, invasion and tumor growth ENSG00000107562 ENSG00000168214 ENSG00000148400 ENSG00000198793 ENSG00000121966 PMC6610018__F5 Association of cGAS-cGAMP-STING signaling with apoptosis ENSG00000183735 ENSG00000164430 PMC6610018__F4 Cross talk between the cGAS-cGAMP-STING pathway and autophagy/mitophagy ENSG00000177169 ENSG00000183735 ENSG00000164430 ENSG00000123240 ENSG00000284099 ENSG00000158828 PMC9682817__F4 Regulatory of miRNAs in tri-lineage differentiation of C3H10T1/2 ENSG00000170365 ENSG00000166278 PMC9682817__F3 Regulatory of miRNAs in tri-lineage differentiation of C3H10T1/2 ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC8914548__F11 TFPI2 suppresses the interaction of TGFB2 pathway regulators to promote endothelial–mesenchymal transition in diabetic nephropathy PMC9410841__F11 Activation of LRP1 Ameliorates Cerebral Ischemia/Reperfusion Injury and Cognitive Decline by Suppressing Neuroinflammation and Oxidative Stress through TXNIP/NLRP3 Signaling Pathway in Mice ENSG00000162711 ENSG00000265972 PMC9707336__F6 M6A methylation profiles of immune cells in type 1 diabetes mellitus ENSG00000177455 ENSG00000087095 ENSG00000103479 ENSG00000002330 ENSG00000170458 ENSG00000179091 ENSG00000102871 ENSG00000104894 ENSG00000130159 ENSG00000127191 ENSG00000026103 PMC9707336__F5 M6A methylation profiles of immune cells in type 1 diabetes mellitus ENSG00000087095 ENSG00000213928 ENSG00000170458 ENSG00000102871 ENSG00000133116 ENSG00000154016 ENSG00000026103 PMC5159669__F7 Proposed models of two separable mTORC1 pathways PMC7503842__F2 Aberrant Wnt signaling favors disease progression in leukemia ENSG00000178860 ENSG00000139193 ENSG00000085117 ENSG00000170558 ENSG00000198793 ENSG00000126778 ENSG00000168646 PMC7503842__F1 Wnt signaling pathways ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000177606 ENSG00000168036 PMC9552419__F9 SAFit2 reduces neuroinflammation and ameliorates nerve injury-induced neuropathic pain ENSG00000108691 ENSG00000108688 ENSG00000196689 ENSG00000277943 PMC8743668__F2 Non‐coding RNA‐associated competitive endogenous RNA regulatory networks: Novel diagnostic and therapeutic opportunities for hepatocellular carcinoma ENSG00000281324 ENSG00000132964 ENSG00000168610 PMC6273223__F2 Genistein (0.01–10 μM) stimulates breast cancer cell proliferation acting through the classical genomic ER pathway and/or through the fast, non-genomic GPER1-mediated pathway ENSG00000113070 ENSG00000146648 PMC7243790__F3 Chloroquine (CQ) and hydroxychloroquine (HCQ) suppress DNA sensing by the cGAS-STING pathway and Toll-like receptor (TLR) signalling ENSG00000239732 ENSG00000163568 ENSG00000125538 ENSG00000276561 PMC8906734__F1 FKBP51 associates with amino acids and polyamine biosynthesis pathways ENSG00000112561 PMC4134342__F2 Sortilin, a novel APOE receptor implicated in Alzheimer disease ENSG00000130164 PMC3716523__F4 TGFB signaling pathway PMC7662576__F4 Host targeted drugs with potential use for Coronavirus disease-19 and their proposed mechanism of action ENSG00000170458 ENSG00000198793 PMC4470864__F6 Pentose phosphate pathway (PPP) is associated with several cancer- and cell-proliferation-related signalling cascades ENSG00000180210 ENSG00000149311 ENSG00000078237 PMC5023176__F13 Cytokine Signalling Network for the Regulation of Inducible Nitric Oxide Synthase Expression in Rheumatoid Arthritis ENSG00000115415 PMC2786808__F8 Pivotal role for glycogen synthase kinase–3 in hematopoietic stem cell homeostasis in mice ENSG00000134982 ENSG00000198793 PMC4092039__F2 G-Protein Coupled Receptors Engage the Mammalian Hippo pathway through F-Actin ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC4092039__F1 G-Protein Coupled Receptors Engage the Mammalian Hippo pathway through F-Actin ENSG00000126016 ENSG00000130545 ENSG00000150457 ENSG00000131023 PMC6933613__F8 Schematic diagram of IL-17A induces excessive autophagy via Src-PP2B-mTOR pathway in neurons under ischemic condition ENSG00000291971 ENSG00000198793 ENSG00000124181 ENSG00000163702 PMC8284339__F4 Integrative Analysis of Human Macrophage Inflammatory Response Related to Mycobacterium tuberculosis Virulence ENSG00000169248 ENSG00000169245 ENSG00000081041 ENSG00000137077 ENSG00000138755 ENSG00000102970 ENSG00000108700 ENSG00000163734 ENSG00000163736 ENSG00000049249 ENSG00000162892 ENSG00000273936 PMC3045562__F1 Neural pathway for habituation in response to odors ENSG00000042832 ENSG00000198125 PMC3036164__F8 Alcama mediates Edn1 signaling during zebrafish cartilage morphogenesis ENSG00000164107 ENSG00000136160 ENSG00000151617 PMC8796266__F1 Therapies for immune-related adverse events associated with immune checkpoint inhibition: from monoclonal antibodies to kinase inhibition ENSG00000169248 ENSG00000169245 ENSG00000186716 ENSG00000198793 ENSG00000138755 ENSG00000006606 ENSG00000010671 PMC3228010__F1 Signaling pathways of sunitinib and sorafenib cardiotoxicity ENSG00000002330 ENSG00000198793 ENSG00000167658 PMC2939393__F1 The Fe-S biogenesis proteins, ISCA and C1orf69 (Iba57 homologue), may impact heme synthesis by affecting the production of succinyl-CoA, a substrate of heme synthesis ENSG00000182511 ENSG00000066926 ENSG00000158578 PMC8371345__F1 Thyroid hormones and the potential for regulating glucose metabolism in cardiomyocytes during insulin resistance and T2DM ENSG00000135218 ENSG00000173599 PMC3204078__F5 SHP-1 activation and modulation on ghrelin signaling to Akt ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC3503557__F5 Network and pathway structure for biologically informative priors in the cancer drug response data study ENSG00000012048 ENSG00000002330 ENSG00000291971 ENSG00000198793 ENSG00000123374 ENSG00000160691 PMC10940682__F6 N-myristoylation is involved in the regulation of multiple cellular signal transduction pathways ENSG00000291603 ENSG00000213658 ENSG00000134982 ENSG00000186716 ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000276920 ENSG00000124181 ENSG00000136448 ENSG00000010671 PMC10940682__F8 S-prenylation is involved in the regulation of multiple cellular signal transduction pathways ENSG00000088888 ENSG00000070831 ENSG00000156299 ENSG00000198793 ENSG00000163914 ENSG00000167965 PMC3598339__F4 Network related to cell cycle and cell death in islets cultured at 23 mM glucose concentration ENSG00000148346 ENSG00000142192 ENSG00000181163 ENSG00000196954 ENSG00000065320 ENSG00000171791 ENSG00000168040 ENSG00000137845 ENSG00000134900 ENSG00000131669 ENSG00000163435 ENSG00000092621 ENSG00000188021 ENSG00000136997 ENSG00000288475 ENSG00000196352 ENSG00000005381 ENSG00000079435 ENSG00000277401 ENSG00000133027 ENSG00000155090 PMC7287162__F7 Key components of the melanogenesis signaling pathway ENSG00000100146 PMC6933397__F5 Molecular mechanism by which NKILA regulates osteogenesis ENSG00000196591 PMC10940682__F4 S-palmitoylation is involved in the regulation of multiple cellular signal transduction pathways ENSG00000164430 ENSG00000281324 ENSG00000134982 ENSG00000168036 ENSG00000168610 ENSG00000146648 ENSG00000169174 ENSG00000026103 PMC8236581__F1 Wnt-Frizzled Signaling Regulates Activity-Mediated Synapse Formation ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6118308__F1 Progression and environmental sensitivity of C ENSG00000171105 ENSG00000066629 ENSG00000291814 ENSG00000138798 ENSG00000168036 ENSG00000120075 ENSG00000146648 PMC3938256__F1 Genetics of lymphatic anomalies ENSG00000019991 ENSG00000176692 ENSG00000183287 ENSG00000198793 ENSG00000269335 ENSG00000117707 ENSG00000037280 ENSG00000179348 ENSG00000138160 ENSG00000203883 ENSG00000150630 PMC12065391__F2 Inflammatory signaling pathways involved in MDS and associated therapeutic targets ENSG00000278718 ENSG00000174125 ENSG00000162711 ENSG00000143546 ENSG00000163220 ENSG00000172936 ENSG00000150455 ENSG00000184216 PMC4871122__F1 Copper transport and regulation in Schizosaccharomyces pombe ENSG00000138495 ENSG00000133028 PMC7057456__F3 Visualization of identified KEGG Cell Cycle pathway routes ENSG00000145604 ENSG00000108055 ENSG00000134982 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000164754 ENSG00000205250 ENSG00000277273 ENSG00000117399 ENSG00000093009 PMC5067249__F1 Schematic representation of the classic, alternative, and neural cholesterol clearance pathways of bile acid synthesis ENSG00000167910 ENSG00000036530 ENSG00000180432 ENSG00000135929 PMC4433279__F4 Silencing of Receptor Tyrosine Kinase ROR1 Inhibits Tumor-Cell Proliferation via PI3K/AKT/mTOR Signaling Pathway in Lung Adenocarcinoma ENSG00000198793 ENSG00000185483 PMC2672887__F1 Model for the regulation of type 1 interferon signalling by filamin B ENSG00000187608 PMC3598339__F3 Network related to lipid metabolism in islets cultured at 23 mM glucose concentration ENSG00000002330 ENSG00000070831 ENSG00000171791 ENSG00000104332 ENSG00000160613 ENSG00000288461 ENSG00000132170 ENSG00000148498 ENSG00000158874 ENSG00000258643 ENSG00000079435 ENSG00000136872 ENSG00000124171 ENSG00000185825 PMC5795989__F1 BMP-triggered signalling pathway and major regulators ENSG00000170365 ENSG00000137834 ENSG00000095739 ENSG00000198742 ENSG00000163914 PMC3598339__F2 Pathway analysis identifies a network of genes related to lipid metabolism in islets cultured at 5.6 mM glucose concentration ENSG00000105894 ENSG00000065609 ENSG00000140262 ENSG00000109084 ENSG00000104969 ENSG00000186480 ENSG00000169884 ENSG00000099194 ENSG00000099804 ENSG00000169174 ENSG00000198911 PMC6915017__F6 CD28 regulates blast thoracic exposure-induced oxidative stress and apoptosis in brain tissue in mice via the PI3K/Nrf2/Keap1 signal pathway ENSG00000125538 PMC3370396__F6 NSAIDs perturbed genes related to thrombosis, fibrinolysis, and PAR signaling ENSG00000134982 ENSG00000122194 ENSG00000104368 PMC7023504__F5 Mitochondrial redox signaling as essential part of branched-chain keto-acid- stimulated secretion of insulin ENSG00000171444 ENSG00000128928 PMC10525998__F10 Transcriptomic Analysis of Light-Induced Genes in Nasonia vitripennis: Possible Implications for Circadian Light Entrainment Pathways PMC7251695__F1 LncRNAs regulate chemoresistance through apoptosis ENSG00000198793 ENSG00000168036 ENSG00000168040 ENSG00000026103 PMC8647006__F1 Regulatory switches, reinforcement, and redundancy in DSB repair pathway choice ENSG00000012048 ENSG00000163961 ENSG00000163104 ENSG00000112130 PMC6468910__F4 ER stress and chemo-resistance: Role of inositol-requiring enzyme 1 alpha (IRE1), activating transcription factor 6 alpha (ATF6), and glucose-regulated protein 78 (GRP78) ENSG00000100290 ENSG00000065485 ENSG00000002330 ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC7251695__F3 LncRNAs regulate chemoresistance through cancer cell stemness ENSG00000125398 ENSG00000168036 ENSG00000136826 PMC7014277__F3 Role of protein phosphatases in the DNA damage checkpoint deactivation ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000166851 PMC5617549__F1 Molecular basis of targeting PFKFB3 as a therapeutic strategy against cancer ENSG00000180210 ENSG00000114268 PMC5617549__F3 The molecular basis of targeting PFKFB3 as a therapeutic strategy against cancer ENSG00000059804 PMC6815035__F5 The miRNA–mRNA interaction networks containing eleven lipid metabolism or deposition related pathways ENSG00000166428 ENSG00000004660 ENSG00000106617 ENSG00000090402 ENSG00000134824 ENSG00000162409 ENSG00000161533 ENSG00000066322 PMC2853417__F5 Differentially expressed genes in the TGFB signaling pathway ENSG00000133937 ENSG00000115297 ENSG00000156574 ENSG00000020633 PMC6815035__F7 MicroRNAs and their regulatory networks in Chinese Gushi chicken abdominal adipose tissue during postnatal late development ENSG00000134853 ENSG00000101306 PMC6815035__F6 MiRNA–mRNA interaction networks containing five cell proliferation and differentiation related pathways ENSG00000106617 ENSG00000162409 ENSG00000118515 ENSG00000134363 ENSG00000134853 ENSG00000127528 ENSG00000178568 PMC7540151__F2 Apoptosis by miR-187 ENSG00000138795 ENSG00000155011 ENSG00000168036 ENSG00000171791 ENSG00000102678 ENSG00000168646 PMC6696099__F1 Proposed targeting approaches involving ACSL isoenzymes in cancer ENSG00000151726 ENSG00000123983 PMC9273593__F6 Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications ENSG00000019991 ENSG00000186810 ENSG00000163739 ENSG00000125538 ENSG00000115419 PMC7540151__F3 EMT by miR-187 ENSG00000169554 ENSG00000124766 ENSG00000196154 ENSG00000101213 PMC5799178__F7 p38 mediates the transcription and the translation of E-selectin by modulating miR-146a and miR-31 ENSG00000125538 ENSG00000175104 ENSG00000179348 PMC7762471__F7 Mechanism underlying ISO’s anti-HCC effects ENSG00000198793 ENSG00000057663 PMC6219034__F10 PRRSV-induced G2/M cell cycle arrest in MARC-145 cells ENSG00000134057 ENSG00000276876 PMC5487699__F2 Regulation and execution of the autophagosomal-lysosomal degradation pathway ENSG00000152348 ENSG00000144848 ENSG00000158828 ENSG00000145782 ENSG00000057663 PMC8767971__F1 COVID-19 and Panax ginseng: Targeting platelet aggregation, thrombosis and the coagulation pathway ENSG00000134460 ENSG00000187608 ENSG00000167749 ENSG00000089127 ENSG00000169047 ENSG00000157601 ENSG00000171791 ENSG00000163737 ENSG00000185010 ENSG00000281244 ENSG00000245848 ENSG00000104549 ENSG00000169429 ENSG00000164400 ENSG00000136869 ENSG00000113889 ENSG00000108342 ENSG00000132170 ENSG00000160752 ENSG00000169245 ENSG00000172936 ENSG00000112115 ENSG00000096717 ENSG00000171855 ENSG00000110921 ENSG00000105329 ENSG00000113161 ENSG00000112715 ENSG00000167508 ENSG00000164305 ENSG00000122194 ENSG00000010671 ENSG00000104368 ENSG00000163631 ENSG00000180210 ENSG00000150782 ENSG00000117525 ENSG00000125538 ENSG00000113520 ENSG00000132906 ENSG00000116044 ENSG00000100906 ENSG00000073756 ENSG00000079999 ENSG00000108691 ENSG00000115415 ENSG00000152904 ENSG00000117601 ENSG00000177606 ENSG00000100985 PMC2853417__F7 Differentially expressed genes in the estrogen receptor signaling pathway ENSG00000171720 ENSG00000142453 ENSG00000146678 ENSG00000108654 ENSG00000131910 ENSG00000141456 PMC5355296__F2 Activating transcription factor 3 is crucial for antitumor activity and to strengthen the antiviral properties of Onconase ENSG00000146592 ENSG00000116717 ENSG00000265972 ENSG00000162772 PMC2853417__F6 Differentially expressed genes in the ERK/MAPK signaling pathway ENSG00000172680 ENSG00000115415 ENSG00000171608 PMC2873055__F9 ACBD3-mediated signaling pathway and cellular regulation ENSG00000182827 ENSG00000133961 PMC7905525__F2 Signaling pathways associated with AQP5 in cancer ENSG00000161798 ENSG00000168036 ENSG00000146648 PMC10179314__F1 PI3K/AKT/mTOR Dysregulation and Reprogramming Metabolic Pathways in Renal Cancer: Crosstalk with the VHL/HIF Axis ENSG00000019991 ENSG00000134086 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC5840025__F9 Cell-specific requirements for STAT proteins and type I IFN receptor signaling discretely regulate IL-24 and IL-10 expression in NK cells and macrophages ENSG00000138378 ENSG00000115415 ENSG00000168610 PMC10885697__F2 MAPKs signaling is obligatory for male reproductive function in a development-specific manner ENSG00000291971 ENSG00000146648 PMC12056752__F1 RAS signaling pathway involves small GTPase switch proteins, NRAS, and KRAS ENSG00000033327 ENSG00000110395 ENSG00000196712 PMC12056752__F2 MicroRNA Signatures: Illuminating Minimal Residual Disease Monitoring in Juvenile Myelomonocytic Leukemia - A Review ENSG00000092847 ENSG00000123908 ENSG00000132341 PMC4524120__F10 Proposed mechanism for the male-specific heart phenotype in insulin-resistant Pcyt2+/− mice ENSG00000135218 ENSG00000185813 ENSG00000173599 PMC7900570__F1 Growth Hormone Signaling Pathway with highlighted Glucose Uptake micropathway ENSG00000112964 ENSG00000115415 ENSG00000169047 ENSG00000168610 ENSG00000140443 PMC7900570__F2 Node activation of Growth Hormone Signaling Pathway for gastric cancer sample GC.11_S19_R1_001 from ENSG00000112964 ENSG00000115415 ENSG00000169047 ENSG00000140443 PMC8403095__F7 Higher-order assemblies in immune signaling: supramolecular complexes and phase separation ENSG00000291603 ENSG00000213658 PMC11731478__F1 Metabolic pathways of riboflavin in E ENSG00000153574 PMC8403095__F1 Higher-order assemblies in immune signaling: supramolecular complexes and phase separation ENSG00000088888 ENSG00000186716 ENSG00000125538 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000168040 ENSG00000184216 ENSG00000026103 PMC5905998__F1 Spatial alterations of De Novo purine biosynthetic enzymes by Akt-independent PDK1 signaling pathways ENSG00000128050 ENSG00000198793 PMC7824032__F1 Methylglyoxal and methylglyoxal pathway in cell response to oxidative stress ENSG00000172005 PMC8819539__F1 Periodontal Ligament Stem Cell-Derived Small Extracellular Vesicles Embedded in Matrigel Enhance Bone Repair Through the Adenosine Receptor Signaling Pathway ENSG00000132646 ENSG00000171791 PMC9563402__F2 MAPK Signaling Pathway in Oral Squamous Cell Carcinoma: Biological Function and Targeted Therapy ENSG00000081041 ENSG00000163739 ENSG00000177606 ENSG00000146648 PMC9602304__F2 Emerging Role of MicroRNAs and Autophagy Mechanism in Pancreatic Cancer Progression: Future Therapeutic Approaches ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000198793 ENSG00000144848 ENSG00000145782 PMC9602304__F1 Emerging Role of MicroRNAs and Autophagy Mechanism in Pancreatic Cancer Progression: Future Therapeutic Approaches ENSG00000102891 ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC10178712__F5 RNA-sequencing analysis revealed the role of trimethylamine-N-oxide (TMAO)-mediated signaling in vascular dementia ENSG00000148346 ENSG00000196296 ENSG00000108691 ENSG00000143546 ENSG00000118785 ENSG00000149968 ENSG00000277943 ENSG00000276799 PMC3749870__F10 CD25 and CD69 induction by A4B1 outside-in signalling requires TCR early signalling complex proteins ENSG00000213658 ENSG00000141968 PMC6509174__F6 Wnt/Beta-catenin signaling pathway regulated by PARG gene silencing during BaP-induced lung cancer ENSG00000134982 ENSG00000168036 ENSG00000227345 PMC6375548__F6 Alternative (backdoor) androgen production and masculinization in the human fetus ENSG00000151632 ENSG00000277893 ENSG00000203859 ENSG00000203857 PMC4801721__F1 Methionine cycle and transsulfuration pathway PMC3751638__F3 METH-regulated genes in METH-pretreated rats ENSG00000066923 ENSG00000284774 ENSG00000196754 ENSG00000166086 ENSG00000119508 ENSG00000167768 ENSG00000143401 ENSG00000171791 ENSG00000122194 ENSG00000148498 ENSG00000053747 ENSG00000277339 ENSG00000150991 ENSG00000082175 ENSG00000176406 ENSG00000146678 ENSG00000076382 ENSG00000170608 ENSG00000126016 ENSG00000110711 ENSG00000183979 ENSG00000181690 ENSG00000166670 ENSG00000168610 ENSG00000214114 ENSG00000148702 ENSG00000139517 ENSG00000026508 ENSG00000184343 ENSG00000080618 ENSG00000188037 ENSG00000183067 ENSG00000276838 ENSG00000138180 PMC6375548__F1 Alternative (backdoor) androgen production and masculinization in the human fetus ENSG00000086696 ENSG00000151632 ENSG00000198610 ENSG00000277893 ENSG00000203857 ENSG00000187134 PMC7211589__F1 This figure illustrates the differential glucose metabolism in a healthy macrophage and in a COVID-19-activated macrophage ENSG00000198793 PMC6396666__F3 Protein–protein interaction networks.Notes: Upexpression genes were analyzed and constructed a network ENSG00000114346 ENSG00000178999 ENSG00000131153 ENSG00000119969 ENSG00000073111 ENSG00000117399 ENSG00000122952 ENSG00000134057 ENSG00000013810 ENSG00000280610 ENSG00000166863 ENSG00000167670 ENSG00000197299 ENSG00000100479 ENSG00000076382 ENSG00000183580 PMC5357538__F2 Wnt, Hedgehog, and Notch canonical signaling pathways ENSG00000134982 ENSG00000167074 ENSG00000164690 ENSG00000128602 ENSG00000163501 PMC6691912__F1 EV production procedure.Exosomes, 50–150 nm, are initially formed by a process of inward budding in early endosomes to form multivesicular bodies ENSG00000110651 ENSG00000010278 ENSG00000135404 PMC2951839__F1 Lower Succinyl-CoA:3-ketoacid-CoA Transferase (SCOT) and ATP Citrate Lyase In Pancreatic Islets of A Rat Model of Type 2 Diabetes: Knockdown of SCOT Inhibits Insulin Release In Rat Insulinoma Cells ENSG00000173599 ENSG00000120437 ENSG00000075239 PMC8166871__F7 LIRCP-regulating network that connects autophagy and carcinogenesis ENSG00000166340 ENSG00000102043 ENSG00000285032 ENSG00000167207 ENSG00000123240 ENSG00000142798 ENSG00000104946 ENSG00000122218 ENSG00000169047 ENSG00000103222 ENSG00000164327 ENSG00000141564 ENSG00000197785 ENSG00000215305 ENSG00000078804 ENSG00000198925 ENSG00000118873 ENSG00000197769 ENSG00000101407 ENSG00000196557 ENSG00000196663 ENSG00000141279 ENSG00000152208 ENSG00000136869 ENSG00000213341 ENSG00000109943 ENSG00000197616 ENSG00000285281 ENSG00000102710 ENSG00000112293 ENSG00000138735 ENSG00000166887 ENSG00000145979 ENSG00000109572 ENSG00000118804 ENSG00000067955 ENSG00000148154 ENSG00000205356 ENSG00000146648 ENSG00000148158 ENSG00000113494 ENSG00000072121 ENSG00000152556 ENSG00000104881 ENSG00000171855 ENSG00000162711 ENSG00000111300 ENSG00000198382 ENSG00000117425 ENSG00000142330 ENSG00000140598 ENSG00000198793 ENSG00000091106 ENSG00000121966 ENSG00000057663 ENSG00000142166 ENSG00000129219 ENSG00000292096 ENSG00000175054 ENSG00000178607 ENSG00000112685 ENSG00000092621 ENSG00000133116 ENSG00000128052 ENSG00000166501 ENSG00000253729 ENSG00000114520 ENSG00000118946 ENSG00000118596 ENSG00000126858 ENSG00000110497 ENSG00000109061 ENSG00000157764 ENSG00000169682 ENSG00000090674 ENSG00000066739 ENSG00000073921 ENSG00000168610 ENSG00000130479 ENSG00000133216 ENSG00000079999 ENSG00000145604 ENSG00000149311 ENSG00000063176 ENSG00000105612 ENSG00000104133 ENSG00000100330 ENSG00000057593 ENSG00000115020 ENSG00000134853 ENSG00000171848 ENSG00000134243 ENSG00000115825 PMC9100033__F1 Disorders of the Calcium Sensing Signaling Pathway: From Familial Hypocalciuric Hypercalcemia (FHH) to Life Threatening Conditions in Infancy ENSG00000069482 ENSG00000042753 ENSG00000036828 PMC4803814__F1 Ras MAP kinase pathway ENSG00000205517 ENSG00000185634 ENSG00000280962 ENSG00000111344 ENSG00000115904 ENSG00000141068 ENSG00000155903 ENSG00000169032 ENSG00000100485 ENSG00000121879 ENSG00000157557 ENSG00000107263 ENSG00000148082 ENSG00000129946 ENSG00000109756 ENSG00000157764 ENSG00000152689 ENSG00000281877 ENSG00000116237 ENSG00000160691 ENSG00000171777 ENSG00000177189 ENSG00000105122 ENSG00000171435 ENSG00000177606 ENSG00000280477 ENSG00000171608 PMC8495134__F1 Epilepsy in the mTORopathies: opportunities for precision medicine ENSG00000100150 ENSG00000114388 ENSG00000266173 ENSG00000198793 ENSG00000145979 PMC2645305__F3 Airway Smooth Muscle Growth in Asthma ENSG00000198793 PMC2276341__F3 Network analysis of target genes ENSG00000140262 ENSG00000171532 ENSG00000135845 ENSG00000106483 ENSG00000160783 PMC9671114__F6 Changes and significance of gut microbiota in children with focal epilepsy before and after treatment ENSG00000090402 ENSG00000002330 ENSG00000198951 ENSG00000172005 PMC2194080__F1 Proposed mechanism of CD4+ T cell priming after Leishmania major infection ENSG00000119888 ENSG00000172936 PMC8231510__F3 CUT Domain Proteins in DNA Repair and Cancer ENSG00000292286 ENSG00000105486 PMC8231510__F2 CUT Domain Proteins in DNA Repair and Cancer ENSG00000149212 ENSG00000086991 ENSG00000080546 ENSG00000079999 PMC7063158__F1 Schematic diagram for T cell activation and mechanism of IP3 activation ENSG00000196531 ENSG00000173599 PMC8546182__F1 Recent Metabolic Advances for Preventing and Treating Acute and Chronic Graft Versus Host Disease ENSG00000073578 ENSG00000089041 PMC3538588__F8 Systems Biology Approach Reveals Genome to Phenome Correlation in Type 2 Diabetes ENSG00000049323 ENSG00000137834 ENSG00000111537 ENSG00000100387 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000164093 PMC3759750__F2 Regulation of prosurvival and apoptotic pathways by ER stress ENSG00000132906 ENSG00000134109 ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 ENSG00000164305 PMC4455918__F1 mTOR signaling pathway ENSG00000198793 PMC86592__F9 LPS-induced signaling pathways leading to activation of transcription and spreading ENSG00000170458 ENSG00000172936 ENSG00000175104 PMC9404696__F7 ANGPTL8 promotes adipogenic differentiation of mesenchymal stem cells: potential role in ectopic lipid deposition ENSG00000130173 ENSG00000168036 PMC3267662__F2 IGF1R-IR/PI3K/Akt/mTOR pathway and its manipulation through diet ENSG00000198793 ENSG00000140443 PMC10609794__F2 The PRG4-CD44 axis in mitigating the pro-inflammatory and pro-fibrotic signaling pathways in DJDs ENSG00000162711 ENSG00000026508 PMC208733__F1 Regulation of the Foxa and Foxo transcription factors through PI3-kinase signaling ENSG00000170608 ENSG00000150907 ENSG00000096088 ENSG00000129514 ENSG00000184481 PMC6206292__F3 Diagram of carbohydrate metabolism pathways with their related DEGs (differentially expressed genes) and DAMs ENSG00000090402 ENSG00000205362 ENSG00000135517 ENSG00000062485 PMC6206292__F5 Brief diagram of amino acid metabolism pathways with related DEGs and DAMs ENSG00000183077 PMC11853609__F9 Schematic model of the mechanism by which PHF8 promotes malignant phenotypes and immune escape of KRAS- or BRAF-mutant CRC cells ENSG00000224320 ENSG00000157764 ENSG00000125347 ENSG00000276561 PMC3731360__F6 Role of CTLA4 in the Proliferation and Survival of Chronic Lymphocytic Leukemia ENSG00000291603 ENSG00000115415 ENSG00000134215 ENSG00000163599 ENSG00000186716 ENSG00000136997 ENSG00000171791 PMC6034754__F4 MicroRNA molecular profiling identifies potential signaling pathways conferring resistance to chemoradiation in locally-advanced rectal adenocarcinoma ENSG00000137834 ENSG00000169554 ENSG00000062598 ENSG00000137674 ENSG00000186716 ENSG00000111837 ENSG00000087842 PMC2438299__F6 Regulation of G1/S transition by the Cdh1/APC-Skp2-p27 cascade in colon cancer Cdh1/APC is critical in regulating Skp2-p27-cyclin E/CDK2 axis, resulting in averting abnormal entry of S phase ENSG00000145604 ENSG00000123374 PMC4725591__F2 BMP signal transduction ENSG00000170365 ENSG00000137834 PMC8239905__F3 COVID‐19‐related coagulopathy: A review of pathophysiology and pharmaceutical management PMC7490227__F10 Silencing of S100A4 downregulated the PI3K/Akt/mTOR pathway, enhanced autophagy, and promoted wound healing of rabbit cornea after alkali burn ENSG00000198793 PMC6496459__F3 Differential regulation and effects of glycolysis induction in GM-DCs upon stimulation over time ENSG00000198793 ENSG00000126353 ENSG00000026103 PMC6496459__F2 Cellular metabolism networks ENSG00000067992 ENSG00000005882 ENSG00000169710 ENSG00000166278 ENSG00000060762 PMC9315842__F2 Ferroptosis defense pathways ENSG00000228716 ENSG00000167468 ENSG00000102967 PMC8421956__F3 Basic science of optic nerve regeneration ENSG00000242689 ENSG00000198793 ENSG00000128342 ENSG00000168610 PMC5572616__F1 Effect of the Hh signaling pathway on the regulation of proliferation and differentiation of SSCs in mammals ENSG00000139549 PMC8507550__F2 The Hedgehog Pathway in Cholangiocarcinoma ENSG00000145632 ENSG00000170558 ENSG00000128602 PMC8507550__F1 The Hedgehog Pathway in Cholangiocarcinoma ENSG00000106571 ENSG00000128602 PMC11674716__F14 Diagram of red KEGG of Non-alcoholic fatty liver disease PMC11674716__F13 Diagram of red KEGG of AMPK signaling pathway ENSG00000180210 ENSG00000171105 ENSG00000135218 ENSG00000005882 ENSG00000198793 ENSG00000284161 ENSG00000001626 ENSG00000164087 ENSG00000026103 PMC11674716__F12 KEGG network diagram of the PPAR signaling pathway ENSG00000157184 ENSG00000150991 ENSG00000100979 PMC3551464__F1 Control of cell adhesion during neuronal migration ENSG00000152092 ENSG00000181788 ENSG00000170558 ENSG00000189056 ENSG00000148219 ENSG00000173406 PMC10375449__F8 Cyclovirobuxine D pretreatment ameliorates septic heart injury through mitigation of ferroptosis ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000168610 PMC11674716__F11 WikiPathway outline of burn-wound healing ENSG00000152661 ENSG00000261371 ENSG00000250799 ENSG00000105329 ENSG00000113070 ENSG00000112715 ENSG00000108821 ENSG00000101680 ENSG00000007171 ENSG00000143632 PMC7791174__F7 Illustrations of TRPV6 as a critical regulator in osteoclastic bone resorption ENSG00000165125 ENSG00000146678 ENSG00000140443 PMC7727543__F1 Key mutations in gene categories represented in MDS/MPN overlap syndromes ENSG00000163930 ENSG00000115524 ENSG00000159216 ENSG00000171456 ENSG00000110395 ENSG00000196712 ENSG00000179295 PMC6899977__F3 The carcinogenic mechanisms of six major microorganisms ENSG00000128602 ENSG00000168610 PMC3764601__F4 The meiotic recombination pathway in C ENSG00000204335 ENSG00000057468 ENSG00000217236 ENSG00000291837 ENSG00000051180 ENSG00000185591 ENSG00000167182 PMC11839971__F1 circ0066187 promotes pulmonary fibrogenesis through targeting STAT3-mediated metabolism signal pathway ENSG00000039537 ENSG00000197299 ENSG00000137996 ENSG00000168610 PMC11956896__F3 The regulatory effects of PCSK9 in T cells and tumor cells ENSG00000130164 ENSG00000136869 ENSG00000131196 ENSG00000169174 PMC7072930__F2 Therapy for fibrodysplasia ossificans progressive (FOP) ENSG00000170365 ENSG00000136960 ENSG00000198793 PMC11956896__F1 Mechanism by which PCSK9 regulates lipid metabolism ENSG00000135218 ENSG00000130164 ENSG00000169174 PMC4449624__F1 Metabolic Alterations Induce Oxidative Stress in Diabetic and Failing Hearts: Different Pathways, Same Outcome ENSG00000042832 ENSG00000175567 PMC5004130__F6 Role of IL-17 Pathways in Immune Privilege: A RNA Deep Sequencing Analysis of the Mice Testis Exposure to Fluoride ENSG00000108702 ENSG00000173039 ENSG00000113520 ENSG00000132693 PMC4335171__F1 Death and dessert: Nutrient signalling pathways and ageing ENSG00000169047 ENSG00000140443 PMC10380638__F5 Schematic presentation of low-dose IR-induced immune effects in the spleen of mice, according to Cho et al ENSG00000113525 PMC7427859__F5 Differentially methylated genes of mTOR signaling pathway at CG (a) and CHH types (b) ENSG00000145604 ENSG00000106070 ENSG00000198793 ENSG00000163914 ENSG00000169047 ENSG00000118515 ENSG00000155792 ENSG00000164327 ENSG00000176641 ENSG00000102104 ENSG00000285069 PMC3270467__F1 Putative galanin-mediated neuronal pro- and antinociceptive mechanisms in the dorsal horn of the spinal cord ENSG00000182687 ENSG00000069482 ENSG00000166573 ENSG00000196689 PMC6294998__F2 New therapeutics based on emerging concepts in pulmonary fibrosis ENSG00000108691 ENSG00000107562 ENSG00000163235 ENSG00000146648 PMC4560409__F8 Neoglycoconjugate Containing the Human Milk Sugar LNFPIII Drives Anti-Inflammatory Activation of Antigen Presenting Cells in a CD14 Dependent Pathway ENSG00000102962 ENSG00000170458 ENSG00000113520 ENSG00000136869 ENSG00000100985 PMC5348798__F3 Cdk5 takes part in DDR through STAT3 pathway ENSG00000154920 ENSG00000136997 ENSG00000168610 PMC8504955__F3 Large portion of the astrocyte proteome is dedicated to perivascular endfeet, including critical components of the electron transport chain ENSG00000183978 ENSG00000185633 ENSG00000162377 ENSG00000067057 ENSG00000073578 ENSG00000117118 ENSG00000178741 ENSG00000105953 ENSG00000101365 ENSG00000166136 ENSG00000143252 ENSG00000074800 ENSG00000100412 ENSG00000146701 ENSG00000152556 PMC10892304__F6 Protein–protein interaction (PPI) network in biosynthesis of plant hormones and signal transduction pathways ENSG00000221818 PMC3867948__F4 Death receptors and the extrinsic pathway of apoptosis ENSG00000102871 ENSG00000168040 ENSG00000026103 PMC8276676__F3 Computational Systems Analyses to Identify Biomarkers and Mechanistic Link in Psoriasis and Cutaneous Squamous Cell Carcinoma ENSG00000166278 ENSG00000175104 ENSG00000163702 PMC10515252__F4 m6A modifications interact with the CRC inflammatory microenvironment ENSG00000120833 ENSG00000142627 ENSG00000115457 ENSG00000112715 ENSG00000165819 PMC8276676__F4 Computational Systems Analyses to Identify Biomarkers and Mechanistic Link in Psoriasis and Cutaneous Squamous Cell Carcinoma ENSG00000166278 ENSG00000175104 ENSG00000163702 PMC3603502__F10 Redox regulation of signaling pathway leading to T-cell activation/proliferation ENSG00000213658 ENSG00000126353 PMC9221329__F1 Implications of Gut Microbiota in Epithelial–Mesenchymal Transition and Cancer Progression: A Concise Review ENSG00000169554 ENSG00000170558 ENSG00000168036 ENSG00000168610 PMC8230587__F3 The Interplay of Alpha-Synuclein and Sphingolipid Signaling in Parkinson’s Disease ENSG00000215021 ENSG00000196591 PMC11655208__F4 Circadian regulation of drug response in mental disorders ENSG00000104899 ENSG00000185015 ENSG00000041982 ENSG00000074410 ENSG00000132170 PMC6445936__F7 Highlights of this study ENSG00000186716 PMC9191825__F2 Human‐host transcriptomic analysis reveals unique early innate immune responses in different sub‐phenotypes of COVID‐19 ENSG00000182511 ENSG00000157933 ENSG00000172005 PMC9191825__F4 Human‐host transcriptomic analysis reveals unique early innate immune responses in different sub‐phenotypes of COVID‐19 ENSG00000134460 ENSG00000162711 ENSG00000113600 ENSG00000115590 ENSG00000091592 ENSG00000168610 ENSG00000274619 ENSG00000088888 ENSG00000184995 ENSG00000130234 ENSG00000134070 ENSG00000136869 ENSG00000175104 ENSG00000062485 PMC9213771__F7 Identification of two lipid phosphatases that regulate sphingosine-1-phosphate cellular uptake and recycling ENSG00000113384 ENSG00000134851 ENSG00000162407 ENSG00000166224 ENSG00000158470 ENSG00000148154 ENSG00000285281 ENSG00000292209 ENSG00000106546 ENSG00000143418 PMC7137032__F2 Current paradigm of asthma endotypes and related therapies ENSG00000137033 ENSG00000145777 ENSG00000166090 PMC9643007__F10 Stromal contributions and potential therapeutic agents ENSG00000149311 ENSG00000157404 ENSG00000157764 ENSG00000101003 ENSG00000291971 ENSG00000131153 ENSG00000171791 ENSG00000147536 PMC3741135__F9 Sirt1 Inhibits Akt2-Mediated Porcine Adipogenesis Potentially by Direct Protein-Protein Interaction ENSG00000096717 ENSG00000026103 PMC9409235__F4 mTOR: A Potential New Target in Nonalcoholic Fatty Liver Disease ENSG00000198793 PMC5045425__F4 Gene expression profiling of normal thyroid tissue from patients with thyroid carcinoma ENSG00000117472 ENSG00000167749 ENSG00000130522 ENSG00000113070 ENSG00000072274 ENSG00000152785 ENSG00000276051 ENSG00000167074 ENSG00000073756 ENSG00000163660 PMC8652287__F2 Biological Adaptations of Tumor Cells to Radiation Therapy ENSG00000144895 ENSG00000142082 ENSG00000060762 PMC8067192__F4 Network analysis performed using ingenuity pathway analysis (IPA) ENSG00000134339 ENSG00000261701 ENSG00000101474 ENSG00000228278 ENSG00000110448 ENSG00000105516 ENSG00000120885 ENSG00000163815 ENSG00000188676 ENSG00000138207 ENSG00000108691 ENSG00000111537 ENSG00000284838 ENSG00000144554 ENSG00000141753 ENSG00000175336 ENSG00000005381 ENSG00000100721 ENSG00000140443 ENSG00000148965 ENSG00000120341 PMC9409235__F3 mTOR: A Potential New Target in Nonalcoholic Fatty Liver Disease ENSG00000177169 ENSG00000162711 ENSG00000239732 ENSG00000143867 ENSG00000150907 ENSG00000112561 ENSG00000136869 ENSG00000265972 PMC9409235__F2 mTOR: A Potential New Target in Nonalcoholic Fatty Liver Disease ENSG00000042832 ENSG00000150907 ENSG00000169047 ENSG00000104549 ENSG00000169710 ENSG00000160741 PMC7407646__F1 TLR4 signaling pathways activated in microglia during neuroinflammation ENSG00000162711 ENSG00000137275 ENSG00000125538 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000168040 ENSG00000168404 ENSG00000175104 ENSG00000064012 ENSG00000164305 ENSG00000285379 PMC11820109__F7 Cdk5-gated light signal ENSG00000142178 ENSG00000132326 ENSG00000179094 ENSG00000105662 ENSG00000164949 PMC7972864__F1 Proposed model of signaling pathway involved in FUC prevented 6-OHDA-induced ROS ENSG00000178573 ENSG00000023909 ENSG00000079999 PMC9643775__F2 New insights into iNKT cells and their roles in liver diseases ENSG00000198053 ENSG00000026103 PMC3126159__F4 Temporal regulation of apoptosis in SeV-infected cells by PI3K ENSG00000183735 ENSG00000107201 ENSG00000120868 PMC7429975__F7 Asymmetrically Substituted Quadruplex-Binding Naphthalene Diimide Showing Potent Activity in Pancreatic Cancer Models ENSG00000128602 ENSG00000164949 PMC4386721__F3 Signaling pathway map PMC7744373__F5 Differentially phosphorylated protein Pathway enrichment analysis ENSG00000180210 ENSG00000169291 ENSG00000002330 ENSG00000134982 ENSG00000163914 ENSG00000089159 PMC4490461__F6 Schematic representations of mammalian homocysteine metabolism PMC3229968__F2 Deciphering the role of Nuclear FactorKB in cellular senescence ENSG00000149311 ENSG00000175104 PMC3229968__F1 Deciphering the role of Nuclear FactorKB in cellular senescence ENSG00000104856 ENSG00000173039 PMC3229968__F3 Deciphering the role of Nuclear FactorKB in cellular senescence ENSG00000198793 ENSG00000096717 PMC7947273__F4 Life Without Thyroid Hormone Receptor ENSG00000126457 ENSG00000135097 PMC5664959__F2 Molecularly Targeted Therapies for p53-mutant Cancers ENSG00000198793 ENSG00000146648 PMC6456454__F1 Inflammatory mediatorsA: Inflammatory mediators with mainly proatherogenic effects are mediated by interleukin-1(IL-1), interleukin-6 (IL-6), and tumor necrosis factorA (TNFA) through nuclear factor kappa beta (NFDB) signaling cascade ENSG00000163661 ENSG00000132693 PMC3717800__F7 Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma ENSG00000169291 ENSG00000002330 ENSG00000157764 PMC4013649__F7 A20 on LPS signaling pathway ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC2923453__F1 Molecular Pathways: Disrupting polyamine homeostasis as a therapeutic strategy for neuroblastoma ENSG00000088826 ENSG00000148832 ENSG00000143450 ENSG00000104904 ENSG00000136997 ENSG00000180304 ENSG00000123505 ENSG00000116649 ENSG00000102172 PMC3534787__F9 Vorinostat, an HDAC Inhibitor Attenuates Epidermoid Squamous Cell Carcinoma Growth by Dampening mTOR Signaling Pathway in a Human Xenograft Murine Model ENSG00000124102 ENSG00000198793 PMC4643408__F2 Signaling pathways associated with CRKL, GAB2, and FRS2.CRKL is activated by multiple types of cell surface receptors including integrin receptors upon binding to extracellular matrix (ECM), cytokine receptors, and growth factor receptors ENSG00000019991 ENSG00000033327 ENSG00000138798 ENSG00000099942 PMC4119864__F3 Signaling epicenters: The role of caveolae and caveolins in volatile anesthetic induced cardiac protection ENSG00000182533 ENSG00000291971 PMC7080238__F9 STING promotes NLRP3 localization in ER and facilitates NLRP3 deubiquitination to activate the inflammasome upon HSV-1 infection ENSG00000162711 ENSG00000164430 ENSG00000125538 PMC8080572__F1 Key signaling molecules in angiogenesis ENSG00000112715 ENSG00000118257 ENSG00000150630 PMC10853571__F6 Molecular mechanisms of tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), serotonin/norepinephrine reuptake inhibitors (SNRIs) and ketamine ENSG00000152495 ENSG00000198793 PMC9143160__F1 PD-1/PD-L1, MDSC Pathways, and Checkpoint Inhibitor Therapy in Ph(-) Myeloproliferative Neoplasm: A Review ENSG00000138798 PMC9515494__F8 Systemic tryptophan homeostasis ENSG00000168003 ENSG00000177169 ENSG00000163406 ENSG00000174358 ENSG00000257008 ENSG00000130234 ENSG00000139287 ENSG00000129167 ENSG00000198793 ENSG00000112394 ENSG00000103257 PMC10853571__F3 Molecular signaling schematic of cytokine hypothesis in the pathogenesis of MDD ENSG00000162711 ENSG00000168036 ENSG00000175567 ENSG00000168610 ENSG00000196628 PMC10853571__F2 The pharmacological mechanism of fluoxetine in astrocytes ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC6678550__F1 Potential signaling pathway between expression of bone morphogenetic protein receptor type II, HDL cholesterol, and vascular remodeling in pulmonary arterial hypertension ENSG00000171759 ENSG00000204217 PMC9515494__F4 Systemic tryptophan homeostasis ENSG00000162882 PMC5514982__F1 Caloric restriction, exercise and AdipoR pathway activate AMPK–SIRT1 and PPAR pathways, which may increase longevity in humans ENSG00000198793 ENSG00000096717 PMC7506548__F2 Non-canonical NFKB pathway ENSG00000104856 ENSG00000183735 ENSG00000264522 ENSG00000142405 ENSG00000131323 ENSG00000127191 PMC2581770__F3 TNFR and LTBR signaling pathways for NFKB activation ENSG00000104856 ENSG00000173039 ENSG00000111321 PMC7506548__F1 Activation and regulation of canonical NFKB pathway ENSG00000102871 ENSG00000082512 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000127191 ENSG00000184216 ENSG00000164342 PMC7457231__F3 SMAD cooperation with different DNA binding partners ENSG00000160973 ENSG00000133937 ENSG00000185155 ENSG00000156574 ENSG00000150457 ENSG00000131023 PMC4673661__F1 Osteocytes and Skeletal Pathophysiology ENSG00000167941 ENSG00000168036 ENSG00000168016 PMC7457231__F6 Cancer cells can traverse the tumor suppressive TGFB bottleneck by accumulating mutations (“X”) that disable the signal transduction pathway ENSG00000167772 ENSG00000121966 PMC7457231__F5 Determinants of TGFB tumor suppression and its subversion in cancer ENSG00000124766 PMC8205588__F1 Ferroptosis in Different Pathological Contexts Seen through the Eyes of Mitochondria ENSG00000167468 ENSG00000115107 PMC7982543__F3 Pathological pathway of “Lipid-toxicity Inflammation” or “Dampness-heat Syndrome”—Insulin Resistance-Metabolic disease ENSG00000125538 ENSG00000132478 ENSG00000136869 PMC5691648__F6 Predicted pathways deregulated during ZIKV infection ENSG00000128272 ENSG00000144895 ENSG00000159461 ENSG00000165280 ENSG00000127022 ENSG00000100219 ENSG00000171791 ENSG00000136155 ENSG00000127191 PMC7457231__F1 TGFB–SMAD pathway in the basal and activated states ENSG00000136807 ENSG00000132964 PMC8558661__F10 Anticancer Effects of Helminthostachys zeylanica Ethyl acetate Extracts on Human Gastric Cancer Cells through Downregulation of the TNF-Alpha-activated COX-2-cPLA2-PGE2 Pathway ENSG00000145321 ENSG00000105205 ENSG00000057663 PMC8877534__F9 Sdy-1 Executes Antitumor Activity in HepG2 and HeLa Cancer Cells by Inhibiting the Wnt/Beta-Catenin Signaling Pathway ENSG00000281324 ENSG00000162337 ENSG00000135446 ENSG00000168036 PMC3878444__F3 The early phase transcriptome of bovine monocyte-derived macrophages infected with Staphylococcus aureus in vitro ENSG00000002330 ENSG00000292357 ENSG00000125347 PMC5640981__F3 Thyroid C-Cell Biology and Oncogenic Transformation ENSG00000132906 ENSG00000002330 ENSG00000160691 PMC3878444__F2 The early phase transcriptome of bovine monocyte-derived macrophages infected with Staphylococcus aureus in vitro ENSG00000050730 ENSG00000173221 ENSG00000108179 ENSG00000172243 ENSG00000197594 ENSG00000177606 ENSG00000082805 ENSG00000121236 ENSG00000146457 ENSG00000110911 ENSG00000090376 ENSG00000198355 PMC3878444__F4 Upstream regulators and their target molecules in datasets as identified by Ingenuity Pathway Analysis (IPA) ENSG00000023445 ENSG00000171855 ENSG00000110330 ENSG00000081041 ENSG00000090104 ENSG00000109320 ENSG00000205220 ENSG00000125347 ENSG00000007171 ENSG00000155307 ENSG00000118503 ENSG00000102245 ENSG00000125538 ENSG00000188404 ENSG00000113520 ENSG00000126353 ENSG00000105810 ENSG00000115009 ENSG00000114520 PMC3157228__F7 Scheme for changes in the molecular pattern of inflammatory signaling, antigen processing, and presentation in attacked myofibers ENSG00000159128 ENSG00000115415 ENSG00000027697 ENSG00000230034 PMC5035969__F1 Schematic presentation of the N-linked core oligosaccharide structure ENSG00000134109 ENSG00000116406 ENSG00000088298 PMC10419312__F3 Agents to target macrophages in CTD-ILD ENSG00000137033 ENSG00000196154 ENSG00000168036 PMC10419312__F2 Macrophages in CTD-ILD ENSG00000108691 ENSG00000275385 ENSG00000169439 PMC3878444__F6 The early phase transcriptome of bovine monocyte-derived macrophages infected with Staphylococcus aureus in vitro ENSG00000167207 PMC5563070__F6 Cell type-specific metabolism of T ENSG00000122966 ENSG00000172005 PMC9105721__F1 Heterozygous Genetic Variants in Autosomal Recessive Genes of the Leptin-Melanocortin Signalling Pathway Are Associated With the Development of Childhood Obesity ENSG00000164129 ENSG00000125851 ENSG00000115138 ENSG00000124089 ENSG00000175426 ENSG00000166603 PMC7065375__F7 Part of the KEGG pathway “Focal adhesion” ENSG00000169291 ENSG00000002330 ENSG00000010810 ENSG00000177606 PMC3717870__F4 Analysis of gene transcription in response to an acute bout of exercise identifies dysregulation of SMAD, CREB, and HDAC activity in LRT ENSG00000136158 ENSG00000167470 ENSG00000143878 ENSG00000119508 ENSG00000159388 ENSG00000113070 ENSG00000070404 ENSG00000122877 ENSG00000099860 ENSG00000170606 ENSG00000116717 ENSG00000171791 ENSG00000162772 ENSG00000104332 ENSG00000166886 ENSG00000124762 ENSG00000136603 ENSG00000109819 ENSG00000075223 ENSG00000172236 ENSG00000144655 ENSG00000123268 ENSG00000127948 PMC8745251__F1 Bile Acid Metabolism to Improve Plasma Lipid and Lipoprotein Profiles ENSG00000198610 ENSG00000167910 ENSG00000180432 ENSG00000099377 ENSG00000122787 ENSG00000135929 PMC8745251__F2 Bile Acid Metabolism to Improve Plasma Lipid and Lipoprotein Profiles ENSG00000138075 ENSG00000160867 ENSG00000167910 PMC7210752__F1 Proposed model for the regulation of pistil growth and ovule primordium initiation ENSG00000127445 ENSG00000110934 PMC8650509__F1 Pharmacological Modulation of Nrf2/HO-1 Signaling Pathway as a Therapeutic Target of Parkinson’s Disease ENSG00000158828 PMC8650509__F4 Pharmacological Modulation of Nrf2/HO-1 Signaling Pathway as a Therapeutic Target of Parkinson’s Disease ENSG00000137857 ENSG00000140279 ENSG00000086991 ENSG00000140254 ENSG00000140274 ENSG00000074771 ENSG00000188747 PMC4812115__F5 Most correlated signaling pathway was the rheumatoid arthritis pathway (http://www.kegg.jp/kegg-bin/show_pathway?map05323) ENSG00000165983 ENSG00000081041 ENSG00000111537 ENSG00000143387 PMC8296592__F8 EGFL6 regulates angiogenesis and osteogenesis in distraction osteogenesis via Wnt/Beta-catenin signaling ENSG00000198759 ENSG00000168036 ENSG00000112715 PMC3521791__F6 Part of the top canonical pathway affected by in vivo LPS administration into the human lung ENSG00000174123 ENSG00000243414 ENSG00000050730 ENSG00000167207 ENSG00000135148 ENSG00000095015 ENSG00000169032 ENSG00000150455 ENSG00000010671 ENSG00000239732 ENSG00000284571 ENSG00000142405 ENSG00000136869 ENSG00000090376 ENSG00000164342 ENSG00000174125 ENSG00000137275 ENSG00000109320 ENSG00000173039 ENSG00000065559 ENSG00000106100 ENSG00000127666 ENSG00000276561 ENSG00000076604 ENSG00000115602 ENSG00000170458 ENSG00000118503 ENSG00000187554 ENSG00000177606 ENSG00000026508 ENSG00000134070 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000132341 PMC6497364__F4 MiR‐125b‐protein and protein‐protein interaction network of differentially expressed genes, with particular focus on AHSG (fetuin‐A), FGF‐23, and TNFRSF11B (osteoprotegerin) ENSG00000023445 ENSG00000118972 ENSG00000226275 ENSG00000110330 ENSG00000213658 ENSG00000164761 ENSG00000145192 ENSG00000173039 ENSG00000111321 ENSG00000087460 ENSG00000141655 PMC3589551__F2 Regulation of LTP induction in the hippocampus by NRG1-ErbB4 signaling through suppressing Src enhancement of NMDARs ENSG00000291971 ENSG00000178568 PMC2930670__F2 Iron redox cycling in aerobic iron metabolism ENSG00000167996 PMC11535355__F7 Proposed model ENSG00000175104 ENSG00000184216 PMC5493774__F9 SUMO pathway plays a crucial role in IBD: model representation of importance of SUMOylation in intestinal health and disease ENSG00000118503 ENSG00000145777 ENSG00000007171 PMC5681992__F3 Schematic overview of the bile acid signaling pathways to the central nervous system ENSG00000066468 ENSG00000160867 ENSG00000077782 PMC5681992__F1 Schematic representation of bile acid synthesis pathways in humans ENSG00000167910 ENSG00000036530 ENSG00000180432 ENSG00000115271 ENSG00000135929 PMC3629761__F3 B-cell receptor (BCR) signaling pathway and potential targets ENSG00000186716 ENSG00000010671 ENSG00000198286 PMC9459608__F1 Kisspeptins and norepinephrine regulate different G-protein-coupled receptor signaling pathways ENSG00000183853 ENSG00000291971 ENSG00000198793 ENSG00000150457 ENSG00000146648 ENSG00000114019 ENSG00000131023 PMC5578700__F1 Bon EPOtit! S1P-Mediated EPO Signaling Whets a Macrophage’s Appetite for Apoptotic Cells ENSG00000153208 ENSG00000135218 ENSG00000140545 ENSG00000187266 PMC6158478__F2 Biochemical pathways of lysophosphatidic acid synthesis and degradation ENSG00000129219 ENSG00000198670 ENSG00000064547 PMC8008022__F3 Apoptosis is triggered through two major pathways referred to as the intrinsic and extrinsic pathways ENSG00000100290 ENSG00000137275 ENSG00000102871 ENSG00000136869 ENSG00000168040 ENSG00000110218 ENSG00000137845 ENSG00000164305 ENSG00000164342 ENSG00000115317 PMC5703744__F1 Two major pathways in the cellular folate cycle ENSG00000284320 ENSG00000228716 ENSG00000196839 ENSG00000124275 ENSG00000116984 PMC7853880__F1 Canonical Wnt/beta‐catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000177606 ENSG00000136997 ENSG00000168036 PMC4449453__F1 Beyond Adjuvants: Immunomodulation strategies to enhance T cell immunity ENSG00000134982 PMC7658481__F6 Pioglitazone effects on TLR and interferon (IFN) pathway ENSG00000184979 ENSG00000183735 ENSG00000213928 ENSG00000187608 ENSG00000115415 ENSG00000033800 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000142166 PMC5610679__F1 Molecular events occurring in Alzheimer’s Disease (AD) following locus coeruleus (LC) norepinephrine (NE) loss and autophagy impairment ENSG00000142192 ENSG00000198793 PMC4777469__F1 Genes and miRNAs involved in the regulation of the intrinsic and extrinsic apoptosis pathway ENSG00000168040 PMC6533856__F1 Leptin metabolism pathway ENSG00000115138 ENSG00000168610 PMC3062410__F2 Networks most highly represented by transcripts differentially associated with HuR after IR treatment ENSG00000196839 ENSG00000138798 ENSG00000144118 ENSG00000177606 ENSG00000137825 ENSG00000130159 ENSG00000104921 ENSG00000127191 ENSG00000146648 ENSG00000196712 ENSG00000026103 PMC2869512__F3 Signaling pathway for zinc prevention of atherosclerosis in monocytes/macrophages and vascular endothelial cells: a proposed hypothesis ENSG00000150782 ENSG00000162692 ENSG00000132693 PMC7354440__F8 PEDV nsp15 antagonizes host antiviral response by degradating the RNA levels of TBK1 and IRF3 ENSG00000183735 ENSG00000088888 ENSG00000107201 PMC6674748__F2 Signaling cascades in axon specification ENSG00000070831 ENSG00000156299 ENSG00000134982 ENSG00000133961 PMC3489757__F1 New insights on the role of CD8+CD57+ T-cells in cancer ENSG00000105329 ENSG00000139187 PMC9504568__F10 1,25-Dihydroxyvitamin D3 Negatively Regulates the Inflammatory Response to Porcine Epidemic Diarrhea Virus Infection by Inhibiting NFKB and JAK/STAT Signaling Pathway in IPEC-J2 Porcine Epithelial Cells ENSG00000115415 ENSG00000168610 PMC9386495__F9 Disrupting the plastidic iron-sulfur cluster biogenesis pathway in Toxoplasma gondii has pleiotropic effects irreversibly impacting parasite viability ENSG00000107798 ENSG00000197429 PMC8010076__F2 Clustering and pathway analyses of proteins quantified in EAE and CPZ ENSG00000166794 ENSG00000291827 ENSG00000002330 ENSG00000187608 ENSG00000135069 ENSG00000185651 ENSG00000230034 ENSG00000196136 ENSG00000063177 ENSG00000076554 ENSG00000143149 ENSG00000122565 ENSG00000105993 ENSG00000163947 ENSG00000157540 ENSG00000169896 ENSG00000151012 ENSG00000116044 ENSG00000138029 ENSG00000163220 ENSG00000281931 ENSG00000131095 ENSG00000168610 ENSG00000198363 ENSG00000132170 ENSG00000011304 ENSG00000058262 ENSG00000145192 ENSG00000122705 ENSG00000118900 ENSG00000114115 PMC5995216__F2 Comparison of the LC3-conjugation pathway during canonical autophagy and Plasmodium-associated autophagy-related (PAAR) response ENSG00000177169 ENSG00000152348 ENSG00000188554 ENSG00000123395 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC5742324__F1 Glucose and glutamine catabolism provide tumor cells with biosynthetic precursors ENSG00000115419 ENSG00000060762 PMC2277498__F3 Pharmokinetic Limitations of Antioxidant Treatment for COPD ENSG00000142192 ENSG00000002330 ENSG00000102871 ENSG00000173039 ENSG00000168040 ENSG00000127191 PMC8515183__F2 Interactions Between Pathogenic Burkholderia and the Complement System: A Review of Potential Immune Evasion Mechanisms ENSG00000039537 ENSG00000244731 ENSG00000166278 ENSG00000122194 ENSG00000236625 PMC4589488__F3 Schematic view of bench-to-bedside aspects of colorectal cancer epigenetics ENSG00000100234 ENSG00000140968 ENSG00000262217 ENSG00000104332 ENSG00000115232 ENSG00000172201 PMC5059177__F1 Pterin and monoamine metabolism ENSG00000228716 ENSG00000171759 PMC7808935__F2 Counteracting CAR T cell dysfunction ENSG00000149311 ENSG00000175054 ENSG00000139187 PMC9994446__F3 Developmental regulation of leaf venation patterns: monocot versus eudicots and the role of auxin ENSG00000113558 PMC4682887__F1 Vaccines against Gonorrhea: Current status and Future Challenges ENSG00000125538 ENSG00000145321 PMC3642145__F2 FIP1L1/PDGFRA+ eosinophil signaling.FIP1L1/PDGFRA+ primary eosinophils express upregulated IL-5 receptor (IL-5RA) and JAK2/STAT5 pathway may be involved in FIP1L1/PDGFRA induced disease development(; ; ) ENSG00000183625 PMC6827038__F5 Effect of Ad-Cyp8b1 on liver and intestine gene expression and mTORC1 signaling in HFD-fed mice ENSG00000160867 ENSG00000105550 ENSG00000180432 PMC9181511__F2 Immune Response in Adipocytes and Their Susceptibility to Infection: A Possible Relationship with Infectobesity ENSG00000169245 ENSG00000108691 ENSG00000111537 ENSG00000125538 ENSG00000138755 ENSG00000108688 ENSG00000108700 ENSG00000277943 PMC8000248__F4 Non-coding RNAs regulating Notch Signaling PMC2606015__F9 Schematic view of the Vav family-regulated signaling pathways of DT40 B-cells ENSG00000095585 ENSG00000291971 ENSG00000134215 ENSG00000186716 ENSG00000152689 ENSG00000010671 PMC7995014__F1 Schematic illustration depicting the association of overnutrition/obesity/excess amino acids to angiotensin‐converting enzyme (ACE2) receptors leading to the hyperactivation of mammalian target of rapamycin (mTOR) ENSG00000130234 ENSG00000198793 PMC3180573__F1 Targeting the Nrf2–Keap1 antioxidant defence pathway for neurovascular protection in stroke ENSG00000178573 ENSG00000284099 ENSG00000079999 PMC11921618__F9 Schematic model illustrating the mechanism of TMEM176B inhibiting OC progression ENSG00000168036 PMC11701242__F10 MTORC1 pathway by condensate ENSG00000198793 ENSG00000155792 ENSG00000167965 ENSG00000143479 PMC5885411__F3 Pathway analysis illustrating differential gene expression and association between gene nodes ENSG00000117724 ENSG00000160789 ENSG00000138778 ENSG00000117650 ENSG00000134057 ENSG00000087586 ENSG00000175216 PMC8327843__F2 Regulatory T cell infiltration in tumors: implications for innovative immune precision therapies ENSG00000108702 ENSG00000186810 ENSG00000102962 ENSG00000151882 ENSG00000179934 ENSG00000184451 ENSG00000102970 PMC4938192__F1 Steroid metabolism pathway ENSG00000151632 ENSG00000187134 PMC12065540__F4 Upregulation and downregulation of active factors, mRNA, and signaling pathways during the ulcer healing process ENSG00000167468 ENSG00000187908 ENSG00000096717 PMC12065540__F1 Pathogenesis of Diabetic Ulcers ENSG00000198793 PMC8771101__F1 Microglia activation, classification and microglia-mediated neuroinflammatory modulators in subarachnoid hemorrhage ENSG00000160888 ENSG00000149311 ENSG00000177575 ENSG00000169245 ENSG00000113600 ENSG00000118785 ENSG00000136869 ENSG00000118520 ENSG00000183160 PMC5676684__F6 Network of miR-93 and miR-21 with putative target genes of important signaling pathways from KEGG enrichment analysis ENSG00000104812 ENSG00000163637 ENSG00000002330 ENSG00000134982 ENSG00000135090 ENSG00000173218 ENSG00000134308 ENSG00000115904 ENSG00000168036 ENSG00000197442 ENSG00000099942 ENSG00000104332 ENSG00000137801 ENSG00000179295 ENSG00000039319 ENSG00000198742 ENSG00000138032 ENSG00000116985 ENSG00000185591 ENSG00000133818 ENSG00000196712 ENSG00000109756 ENSG00000171105 ENSG00000172380 ENSG00000101109 ENSG00000044446 ENSG00000281877 ENSG00000175029 ENSG00000072803 ENSG00000081189 ENSG00000177565 ENSG00000197461 ENSG00000117020 ENSG00000198176 ENSG00000101849 ENSG00000285485 ENSG00000146648 ENSG00000204217 ENSG00000080839 PMC7503332__F2 Schematic signaling pathway of TLR7 and 9 ENSG00000239732 ENSG00000172936 ENSG00000276561 ENSG00000184216 PMC11853781__F3 Luteolin multi-pathway treatment of IBD ENSG00000168610 ENSG00000079999 PMC11853781__F4 Multi-pathway mechanisms of luteolin in inhibiting colorectal cancer ENSG00000162711 ENSG00000146648 ENSG00000079999 PMC4174300__F4 Innate immunity to dengue virus infection and subversion of antiviral responses ENSG00000213928 ENSG00000105397 ENSG00000127481 PMC4174300__F3 Innate immunity to dengue virus infection and subversion of antiviral responses ENSG00000088888 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC3510027__F3 Genome-Scale RNA–Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington's Disease ENSG00000137713 ENSG00000127445 ENSG00000112640 ENSG00000171791 ENSG00000166851 ENSG00000121879 ENSG00000102854 ENSG00000126458 ENSG00000168522 PMC3510027__F2 Genome-Scale RNA–Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington's Disease ENSG00000137713 ENSG00000142192 ENSG00000180182 ENSG00000148773 ENSG00000138039 ENSG00000137074 ENSG00000197386 ENSG00000111321 ENSG00000168615 ENSG00000139832 ENSG00000164305 ENSG00000137496 PMC3594740__F1 TLR signaling ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC8660693__F1 Emerging RNA-Binding Activity of cGAS in Innate Antiviral Response ENSG00000164430 PMC7023858__F3 IGFBP-3 was a predicted target of SAN by bioinformatics analysis ENSG00000213658 PMC5422801__F6 Hippo–YAP pathway mediates physiological resistance to gemcitabine ENSG00000158825 ENSG00000150457 ENSG00000114019 ENSG00000131023 PMC9317325__F3 Perivascular Mesenchymal Stem/Stromal Cells, an Immune Privileged Niche for Viruses? ENSG00000178860 ENSG00000183735 ENSG00000088888 ENSG00000187608 ENSG00000105397 ENSG00000110651 ENSG00000172936 ENSG00000135828 ENSG00000276561 ENSG00000121966 ENSG00000164342 ENSG00000162576 PMC4040611__F5 An MAPK network downstream of SDF-1/CXCR4 signaling in breast CSCs ENSG00000163629 ENSG00000115904 ENSG00000281877 ENSG00000173327 ENSG00000089022 ENSG00000130669 ENSG00000121966 PMC8393567__F2 GSK3 as a Regulator of Cytoskeleton Architecture: Consequences for Health and Disease ENSG00000154764 PMC2724989__F1 Macrophage activation by endogenous danger signals ENSG00000183735 ENSG00000131323 ENSG00000168040 ENSG00000135828 ENSG00000175104 ENSG00000127191 PMC9103623__F1 Prolonged Mechanical Ventilation: Outcomes and Management ENSG00000150907 ENSG00000198793 ENSG00000136869 PMC2910166__F7 drr-2 encodes an eIF4H that acts downstream of TOR in diet-restriction-induced longevity of C. elegans ENSG00000106682 ENSG00000084733 PMC8889574__F1 Impact of High Dose Glucocorticoids on Bone Health and Fracture Risk in Systemic Vasculitides ENSG00000163599 ENSG00000005381 PMC11842380__F12 Signaling pathways that the exosome may regulate ENSG00000111837 PMC4572253__F1 Homocysteine metabolism PMC7813969__F1 Sex bias of females in survival from cancer and infections. Is X the answer? ENSG00000111537 PMC3843359__F2 MAPK signaling pathway is upregulated in OSI-906 resistant CRC lines ENSG00000171105 ENSG00000005882 ENSG00000198793 PMC11813976__F2 Molecular mechanisms of STAT3 signaling pathway in CRC ENSG00000087095 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000184371 ENSG00000168610 PMC4472073__F2 Mechanism of castrate-resistant prostate cancer.Notes: 1) Androgens bind and activate the AR despite the castration of testes-derived androgens ENSG00000132341 PMC9454891__F9 Apigetrin Promotes TNFAlpha-Induced Apoptosis, Necroptosis, G2/M Phase Cell Cycle Arrest, and ROS Generation through Inhibition of NFKB Pathway in Hep3B Liver Cancer Cells ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC7243914__F5 Immune signaling responses occurring in chickens infected with Salmonella ENSG00000187796 ENSG00000168036 ENSG00000065559 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000106100 ENSG00000157240 PMC7243914__F4 Immune signaling pathways in bovine monocytes ENSG00000169291 ENSG00000239732 ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC7316088__F3 Hyperactivation of the ATR/CHK1/WEE1 pathway leads to acquired resistance to PARP inhibitors ENSG00000175054 ENSG00000164053 ENSG00000092853 PMC7316088__F2 ATR/CHK1/WEE1 pathway compensates for the replicative stress induced by gemcitabine ENSG00000175054 ENSG00000164053 ENSG00000092853 ENSG00000263042 PMC5393594__F4 Comparative expression profiling of testis-enriched genes regulated during the development of spermatogonial cells ENSG00000066923 ENSG00000155087 ENSG00000042813 ENSG00000128040 PMC11901387__F1 Effect of the microbiota on drug resistance in HCC ENSG00000162711 ENSG00000198793 ENSG00000136869 ENSG00000168610 ENSG00000146648 ENSG00000106546 PMC5214938__F1 Cross-regulation between interleukin-1 (IL-1) and type-1 interferon (IFN) inflammatory pathways as exemplified during Mtb infection ENSG00000162711 ENSG00000183735 ENSG00000164430 ENSG00000138135 ENSG00000115590 ENSG00000163568 ENSG00000073756 ENSG00000115594 ENSG00000142166 PMC5835759__F1 Interactions among Protein Kinase C Alpha (PRKCA), NOS3, and BDKRB2 gene products within the ACE inhibitor pathway may affect the antihypertensive response to enalapril ENSG00000087245 ENSG00000168398 PMC8226943__F2 Redox and Anti-Inflammatory Properties from Hop Components in Beer-Related to Neuroprotection ENSG00000162711 ENSG00000181019 ENSG00000115415 ENSG00000079999 PMC9201217__F1 Toll-Like Receptors in Radiotherapy- and Chemotherapy-Induced Oral Mucositis: A Concise Review ENSG00000189403 ENSG00000172936 PMC2990976__F2 TNFA signaling pathways to NFKB activation ENSG00000102871 ENSG00000127191 PMC9028769__F6 Human Papillomavirus 16 E6 Suppresses Transporter Associated with Antigen-Processing Complex in Human Tongue Keratinocyte Cells by Activating Lymphotoxin Pathway ENSG00000232326 ENSG00000111321 PMC9201217__F2 Toll-Like Receptors in Radiotherapy- and Chemotherapy-Induced Oral Mucositis: A Concise Review ENSG00000239732 ENSG00000187554 ENSG00000189403 ENSG00000172936 ENSG00000136869 PMC3942836__F1 Schematic review ENSG00000164690 ENSG00000128602 ENSG00000121966 PMC5858164__F7 Working model of endothelial specific elevated miRNA302-367 attenuating embryonic hindbrain developmental angiogenesis by targeting CDC42 and CCND1 multiple pathways ENSG00000070831 ENSG00000149269 ENSG00000135446 ENSG00000105810 PMC8085478__F1 Sclerotic chronic GVHD: you may WANT to block WNT ENSG00000281324 ENSG00000134982 ENSG00000168036 PMC7812258__F2 Mechanisms through which TLRs orchestrate pro‐tumour responses ENSG00000184995 ENSG00000171791 PMC7812258__F1 Non‐canonical functions of TLRs ENSG00000239732 ENSG00000136869 ENSG00000057663 PMC9265395__F3 Diverse Functions of KDM5 in Cancer: Transcriptional Repressor or Activator? ENSG00000073614 ENSG00000136997 ENSG00000105810 PMC2637184__F1 New central scaffold for metastasis: parsing HEF1/Cas-L/NEDD9 ENSG00000129474 ENSG00000094631 ENSG00000170365 ENSG00000107562 ENSG00000114346 ENSG00000078747 ENSG00000163235 ENSG00000010810 ENSG00000099942 ENSG00000121966 PMC3660716__F1 Intracellular signaling pathways recruited by leptin ENSG00000198793 ENSG00000168610 PMC11165723__F3 Journey of a generation: advances and promises in the study of primordial germ cell migration ENSG00000157404 ENSG00000107562 ENSG00000169071 ENSG00000197892 ENSG00000291971 ENSG00000121966 PMC11650354__F2 Inhibition of the non-canonical Wnt signaling pathway by WIF1 ENSG00000156076 ENSG00000155011 PMC8678483__F8 Different Molecular Weight Polysaccharides From Dendrobium officinale Kimura & Migo on Human Colorectal Cancer and Transcriptome Analysis of Differentially Expressed Genes ENSG00000168040 ENSG00000115317 PMC11650354__F1 Inhibition of the Wnt/Beta-catenin signaling pathway by WIF1 ENSG00000156076 ENSG00000137673 PMC11650354__F4 DKK3-related signaling pathways in Wnt/Beta-catenin and non-canonical Wnt signaling ENSG00000050165 ENSG00000136997 ENSG00000168036 ENSG00000168646 PMC11650354__F3 Inhibition of the PI3K/Akt, NFKB, and TGFB signaling pathways by WIF1 ENSG00000087245 ENSG00000156076 ENSG00000198793 ENSG00000100985 PMC11650354__F5 DKK3’s inhibition of the PI3K/Akt signaling pathway ENSG00000198793 ENSG00000163914 ENSG00000050165 PMC5983834__F4 PI3K-AKT signaling pathway ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000136997 PMC7198545__F8 TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000009790 PMC2383925__F9 MiRNA model for the molecular pathogenesis of recurrent ovarian cancer ENSG00000066468 ENSG00000157764 ENSG00000138798 ENSG00000105698 ENSG00000171791 ENSG00000100985 PMC8610166__F2 Targeting myeloid-derived suppressor cells for cancer therapy ENSG00000108691 ENSG00000140287 ENSG00000187764 ENSG00000118520 ENSG00000121807 PMC8590100__F3 Innate immune remodeling by short‐term intensive fasting ENSG00000152348 ENSG00000123395 ENSG00000198382 ENSG00000002330 ENSG00000083290 ENSG00000198793 ENSG00000155792 ENSG00000167965 ENSG00000099940 ENSG00000136874 ENSG00000057663 ENSG00000062716 ENSG00000183735 ENSG00000144848 ENSG00000189403 ENSG00000175104 ENSG00000145782 PMC7680678__F1 Therapeutic strategies have been developed to target various steps in the PI3K/AKT/mTOR pathway, thereby blocking cell proliferation, growth and survival ENSG00000198793 ENSG00000146648 PMC10216727__F3 Proposed mechanism of vagus-mediated liver regeneration ENSG00000168610 PMC6003401__F6 Transflammation: How Innate Immune Activation and Free Radicals Drive Nuclear Reprogramming ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC10216727__F2 Role and function of FOXM1 in pulmonary fibrosis ENSG00000087245 ENSG00000134057 ENSG00000166851 ENSG00000168610 PMC2768836__F1 Role of clathrin adaptor proteins in melanosome biogenesis ENSG00000102189 ENSG00000137177 PMC7460646__F2 Inflammation contributes to leptin resistance in the brain at the hypothalamic arcuate nucleus, and as a result, alters food intake and energy expenditure leading to obesity ENSG00000162924 ENSG00000168610 PMC12112539__F1 IL-23 production and signaling pathway in the context of inflammatory bowel disease pathogenesis ENSG00000162594 ENSG00000138378 ENSG00000105397 ENSG00000177606 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000168610 ENSG00000115594 ENSG00000143954 PMC9294450__F3 Erectile Dysfunction: Key Role of Cavernous Smooth Muscle Cells ENSG00000173599 ENSG00000182621 PMC10216727__F6 EGFR/mTOR signaling pathways that regulate FOXM1 are involved in Beta-cell proliferation ENSG00000198793 ENSG00000146648 PMC3288293__F1 Molecular mechanism of senescence ENSG00000096717 ENSG00000142082 PMC12112539__F2 IL-23/IL-23R axis orchestrates innate and adaptive immune responses in the inflamed gut mucosa ENSG00000162594 ENSG00000138378 ENSG00000105397 ENSG00000134982 PMC4174300__F2 Innate immunity to dengue virus infection and subversion of antiviral responses ENSG00000088888 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC4449286__F5 Excess of rare, inherited truncating mutations in autism ENSG00000100354 ENSG00000204120 ENSG00000292232 ENSG00000106070 ENSG00000146830 ENSG00000244462 PMC2697172__F8 Sub-network associated with the Wnt signaling pathway ENSG00000120656 ENSG00000168066 ENSG00000065526 ENSG00000163914 ENSG00000173599 ENSG00000130699 ENSG00000079432 ENSG00000138606 ENSG00000133961 ENSG00000128602 ENSG00000169375 ENSG00000112742 PMC9386258__F1 Benzo(a)pyrene and cardiovascular diseases: An overview of pre-clinical studies focused on the underlying molecular mechanism ENSG00000110711 ENSG00000149968 ENSG00000125538 ENSG00000162692 ENSG00000140465 ENSG00000106546 PMC8236819__F2 Pathophysiologic Role of Neurotransmitters in Digestive Diseases ENSG00000162711 ENSG00000087245 ENSG00000100985 ENSG00000146648 ENSG00000149295 PMC8608597__F9 Super-enhancer-driven lncRNA-DAW promotes liver cancer cell proliferation through activation of Wnt/Beta-catenin pathway PMC5896787__F2 Emerging concepts for immune checkpoint blockade-based combination therapies ENSG00000291603 ENSG00000173599 PMC8101994__F8 Proposed role of PD-L1 on contraction of activated effector T cells ENSG00000134982 ENSG00000198793 PMC4854959__F1 Androgen signal pathways ENSG00000291971 ENSG00000129214 PMC6343712__F6 miR-300 mediates the SP1/MMP9 pathway in BCa ENSG00000185591 ENSG00000100985 PMC6678716__F2 CSCs-activated signaling pathways: Schematic representation of the signaling pathway responsible for induction and maintenance of CSC state ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000150457 ENSG00000128602 ENSG00000168610 ENSG00000131023 PMC2837360__F1 Canonical Wnt/Beta-catenin pathway (modified after ()) ENSG00000169218 ENSG00000134982 PMC6784892__F4 Two intracellular and cell type-specific bacterial symbionts ENSG00000188107 PMC3637970__F1 Transforming growth factorB (TGFB) signaling pathway ENSG00000137834 ENSG00000125968 PMC9266365__F8 Metformin Attenuates UVA-Induced Skin Photoaging by Suppressing Mitophagy and the PI3K/AKT/mTOR Pathway ENSG00000149311 ENSG00000198793 ENSG00000158828 PMC7690210__F1 Activation pathways of the complement system ENSG00000039537 ENSG00000009724 ENSG00000113600 ENSG00000291559 ENSG00000244731 ENSG00000166278 PMC7264474__F1 Ceramide and Sphingosine 1-Phosphate in Liver Diseases ENSG00000139624 ENSG00000063176 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000118785 ENSG00000143418 ENSG00000072080 PMC5428476__F10 Model depicting the involvement of autophagy-lysosomal system in apigenin-induced degradation of Beta-catenin during Wnt signaling ENSG00000281324 ENSG00000162337 ENSG00000198793 PMC10986035__F5 Pattern diagram for the role of NCAPD3 in NSCLC cell proliferation and apoptosis ENSG00000151503 ENSG00000135446 PMC11602425__F3 Metabolic reprogramming drives MASLD progression ENSG00000169248 ENSG00000162711 ENSG00000161921 ENSG00000100344 ENSG00000198793 ENSG00000164362 ENSG00000168610 PMC11602425__F2 Metabolic reprogramming drives HCC progression ENSG00000180210 ENSG00000105251 ENSG00000198793 ENSG00000136997 ENSG00000196092 ENSG00000078237 ENSG00000089163 ENSG00000115419 ENSG00000159399 PMC11602425__F1 Metabolic reprogramming of tumor cells ENSG00000159399 PMC6747339__F1 Schematic representation of ERK1,2 signalling regulation of channels and transporters along the nephron ENSG00000152266 ENSG00000080166 PMC3882431__F6 Schematic representation of the proposed pathway by which deficiency of FXR activates the STAT3 signaling pathway in the liver ENSG00000168610 PMC4254673__F8 Proposed model for autophagy and metastasis mediated by mTOR signaling ENSG00000108849 ENSG00000002330 ENSG00000198793 PMC7662528__F6 RGS Proteins as Critical Regulators of Motor Function and Their Implications in Parkinson’s Disease ENSG00000148908 ENSG00000136869 ENSG00000168040 PMC3940357__F1 Frizzled homolog proteins, microRNAs and Wnt Signaling in Cancer ENSG00000087095 ENSG00000156076 ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC11120667__F12 Proposed model of the mechanisms of action of female M ENSG00000132906 ENSG00000128272 ENSG00000168040 ENSG00000146648 ENSG00000064012 ENSG00000164305 ENSG00000196689 ENSG00000026103 PMC11120667__F11 Proposed model of the mechanisms of action of male M ENSG00000132906 ENSG00000128272 ENSG00000168040 ENSG00000146648 ENSG00000064012 ENSG00000164305 ENSG00000196689 ENSG00000026103 PMC12052780__F5 EVs in macrophage polarization within the ovarian tumor microenvironment ENSG00000253293 ENSG00000272398 ENSG00000107485 ENSG00000096717 ENSG00000168610 ENSG00000114166 PMC12052780__F4 Figure illustrates how various molecular factors drive TAM polarization and chemoresistance in the OC microenvironment ENSG00000133110 ENSG00000214078 ENSG00000148926 ENSG00000171049 ENSG00000073792 ENSG00000107485 ENSG00000102678 ENSG00000126091 PMC3928842__F1 TLRs signaling pathway ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC3660182__F1 Glia-mediated detrimental and beneficial inflammatory pathways in PD ENSG00000005381 ENSG00000157240 PMC12052780__F1 Wnt and PI3K/AKT pathways involved in macrophage polarization and metastatic progression in the tumor microenvironment of ovarian cancer ENSG00000177575 ENSG00000115415 ENSG00000168036 ENSG00000118520 PMC10484658__F2 Schematic diagram of ERS in renal resident cells in LN ENSG00000128272 ENSG00000100219 ENSG00000162692 PMC3660182__F4 Crosstalk between inflammatory and Wnt/Beta-catenin signaling pathways in MPTP-induced SVZ plasticity ENSG00000138798 ENSG00000168036 ENSG00000125084 PMC9299865__F1 Key role of the NAD biosynthetic enzyme nicotinamide mononucleotide adenylyltransferase in regulating cell functions ENSG00000105835 ENSG00000123572 ENSG00000278488 PMC4176007__F3 IL-6 synthesis and regulation of IL-6 mRNA stability by Arid5a ENSG00000196843 ENSG00000172936 ENSG00000136869 PMC7564205__F5 NRP1-ABCB8 pathway: Schematic representation of the NRP1-ABCB8 pathway in regulating iron homeostasis, iron-dependent oxidative stress, mitochondrial function and cellular senescence ENSG00000182511 ENSG00000197150 ENSG00000162692 PMC7729316__F1 Therapeutic approaches targeting tumor angiogenesis ENSG00000166292 ENSG00000128917 ENSG00000125968 PMC5769625__F2 Layers of gene expression control in primed human PSCs ENSG00000147596 ENSG00000134982 ENSG00000168036 ENSG00000102974 PMC5583567__F3 Chronic Cigarette Smoke Mediated Global Changes in Lung Mucoepidermoid Cells: A Phosphoproteomic Analysis ENSG00000198793 ENSG00000155792 ENSG00000160691 PMC8645368__F2 Immune Checkpoint Inhibitor Therapy for Bone Metastases: Specific Microenvironment and Current Situation ENSG00000108691 ENSG00000107562 PMC1559676__F1 The unfolded protein response ENSG00000128272 ENSG00000100219 PMC3164770__F5 FLCN pathway ENSG00000002330 ENSG00000052795 ENSG00000217128 ENSG00000087842 PMC9463442__F7 Regulation and role of RNAPII-generated nascent RNA to guide DNA end resection and DSB repair by HR ENSG00000012048 ENSG00000113360 PMC9294638__F2 Emerging Role of Non-Coding RNAs in Senescence ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11941683__F1 Summary of healing stages following a bone fracture ENSG00000178860 ENSG00000170365 ENSG00000137834 ENSG00000134982 ENSG00000168036 PMC6823706__F3 Molecular mechanism of inflammatory adipokines involved in the pathogenesis of diabetic associated fatty liver disorders via suppression of insulin signaling resulting in insulin resistance ENSG00000150907 ENSG00000125538 ENSG00000198793 ENSG00000173599 PMC9294638__F4 Emerging Role of Non-Coding RNAs in Senescence ENSG00000198793 ENSG00000135932 PMC8176847__F2 Programmed cell death in stem cell-based therapy: Mechanisms and clinical applications ENSG00000168040 ENSG00000164305 PMC8176847__F1 Programmed cell death in stem cell-based therapy: Mechanisms and clinical applications ENSG00000132906 ENSG00000164305 ENSG00000115317 PMC6823706__F2 Molecular mechanism of Fetuin-A involved in the pathogenesis of diabetic associated fatty liver disorders via suppression of insulin signaling resulting in insulin resistance ENSG00000170458 ENSG00000172936 ENSG00000136869 PMC11847854__F3 Saikosaponin A-target-pathway network ENSG00000087245 ENSG00000128052 ENSG00000177606 ENSG00000123374 ENSG00000171791 ENSG00000112715 ENSG00000166851 ENSG00000073756 ENSG00000146648 ENSG00000196396 ENSG00000140443 ENSG00000179295 PMC8487719__F1 Hedgehog signaling pathway ENSG00000106571 ENSG00000128602 ENSG00000105204 PMC3493591__F5 Constitutive ß-Catenin Signaling by the Viral Chemokine Receptor US28 ENSG00000134982 ENSG00000168036 PMC3712869__F4 Smooth Muscle Differentiation and Patterning in the Urinary Bladder ENSG00000103241 ENSG00000164690 ENSG00000128602 PMC3880284__F4 Human Mammospheres Secrete Hormone-Regulated Active Extracellular Vesicles ENSG00000182718 ENSG00000090316 ENSG00000136541 ENSG00000197429 ENSG00000187017 ENSG00000140545 ENSG00000277150 ENSG00000163631 PMC6980436__F1 Heme metabolism and the microglial toll‐like receptor 4 (TLR4) signaling pathway following SAH: In the subarachnoid space, free heme is metabolized by heme oxygenase (HO)‐1, releasing iron (Fe2+), biliverdin, and carbon monoxide (CO) ENSG00000239732 ENSG00000189403 ENSG00000172936 ENSG00000136869 PMC5355173__F2 Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells ENSG00000198793 ENSG00000169047 ENSG00000155792 ENSG00000168036 ENSG00000167965 ENSG00000168646 PMC5355173__F3 Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells ENSG00000281324 ENSG00000106571 ENSG00000134982 ENSG00000168036 ENSG00000123374 PMC11693731__F7 Diagram of catalpol enhance Shh signaling pathway to promote neurogenesis and synaptogenesis by regulating mitochondria ENSG00000164690 ENSG00000128602 PMC5355173__F8 Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells ENSG00000281324 ENSG00000170558 ENSG00000168036 ENSG00000105810 ENSG00000096717 ENSG00000277641 ENSG00000168646 ENSG00000125084 PMC14940__F10 A signaling pathway of c-Met for cell scattering ENSG00000019991 ENSG00000163914 ENSG00000160293 PMC4851234__F2 Negative regulators of necroptosis ENSG00000137275 ENSG00000102871 ENSG00000138032 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC3975104__F2 A simplified model of some of the signaling pathways leading to LTD of the pf-PC synapse ENSG00000173599 ENSG00000145321 ENSG00000140443 PMC7793877__F5 Integrative Analysis Reveals Common and Unique Roles of Tetraspanins in Fibrosis and Emphysema ENSG00000137713 ENSG00000156735 ENSG00000141551 ENSG00000105329 ENSG00000130522 ENSG00000165752 ENSG00000151365 ENSG00000173039 ENSG00000087586 ENSG00000162924 ENSG00000120885 ENSG00000162772 ENSG00000147854 ENSG00000106546 ENSG00000144366 ENSG00000160867 ENSG00000135446 ENSG00000132646 ENSG00000133169 ENSG00000132326 ENSG00000123374 ENSG00000179094 ENSG00000139687 ENSG00000026103 PMC4196646__F1 Signalling pathways connected to autophagy ENSG00000198793 ENSG00000168036 PMC5796046__F3 PB1-F2 virulence ENSG00000162711 ENSG00000183735 ENSG00000136436 ENSG00000088888 ENSG00000125538 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000276561 PMC5265918__F9 Atorvastatin inhibits insulin synthesis by inhibiting the Ras complex (Ras/Raf/extracellular signal-regulated kinase/CREB) in INS-1 cells ENSG00000005882 PMC7374820__F5 Ingenuity Pathway Analysis (IPA) of network of eight DE genes ENSG00000172680 ENSG00000111057 ENSG00000128951 ENSG00000168938 ENSG00000127334 ENSG00000109814 ENSG00000083857 ENSG00000159167 ENSG00000142910 ENSG00000176692 ENSG00000106617 ENSG00000138613 ENSG00000149968 ENSG00000141279 ENSG00000130699 ENSG00000162390 ENSG00000171793 ENSG00000100417 ENSG00000184205 PMC5511151__F7 Mechanisms underlying crosstalk between Wnt/Beta-catenin signaling and insulin signaling via Irs1 during hepatocarcinogenesis ENSG00000169047 PMC11278952__F3 Alterations of bile acids involved in the synthesis pathway in HD ENSG00000167910 ENSG00000036530 ENSG00000180432 ENSG00000115271 ENSG00000135929 PMC5967641__F1 NAD+ biosynthesis, consumption and salvage pathways ENSG00000105835 ENSG00000123572 ENSG00000157064 ENSG00000173614 PMC5471278__F5 Regulatory network model of DNA replication coupled with nicotinamide ENSG00000112118 ENSG00000073111 ENSG00000096717 PMC5471278__F3 Interaction network model ENSG00000105722 ENSG00000134982 ENSG00000080345 ENSG00000291971 ENSG00000125827 ENSG00000149308 ENSG00000111321 ENSG00000120885 ENSG00000171791 ENSG00000012174 ENSG00000076003 ENSG00000198056 ENSG00000153827 ENSG00000136002 ENSG00000135506 ENSG00000012048 ENSG00000038382 ENSG00000178607 ENSG00000011422 ENSG00000132383 ENSG00000014138 ENSG00000051180 ENSG00000105810 ENSG00000101191 ENSG00000177084 ENSG00000177425 ENSG00000124422 ENSG00000114346 ENSG00000116044 ENSG00000092853 ENSG00000131747 ENSG00000139618 ENSG00000068028 ENSG00000127586 ENSG00000117862 ENSG00000077232 ENSG00000175193 ENSG00000134057 ENSG00000213619 ENSG00000143476 ENSG00000167325 ENSG00000186010 ENSG00000171848 ENSG00000197299 ENSG00000171759 ENSG00000070950 ENSG00000149554 PMC9173662__F1 Complement pathways ENSG00000244414 ENSG00000120054 ENSG00000000971 ENSG00000244731 ENSG00000120885 ENSG00000166278 ENSG00000132693 ENSG00000182326 ENSG00000236625 ENSG00000178772 ENSG00000288512 ENSG00000196352 ENSG00000117335 ENSG00000080618 PMC10688769__F4 miRNA alterations affect cartilage synthesis ENSG00000178860 ENSG00000139219 ENSG00000154736 ENSG00000125398 PMC8932121__F2 Inflammation in neurodegeneration: novel insights into the role of the immune system in C9orf72 HRE-mediated ALS/FTD ENSG00000162711 ENSG00000172936 ENSG00000175104 PMC6073096__F4 Simplified DNA repair pathway diagram ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000051180 ENSG00000138385 ENSG00000139618 PMC10688769__F2 Cell-produced SASP affects OA ENSG00000178860 ENSG00000139219 ENSG00000154736 ENSG00000125398 ENSG00000088305 ENSG00000158859 PMC7263368__F1 Representation of Hippo-Yap core kinase signaling cascade ENSG00000101109 ENSG00000164093 ENSG00000150457 ENSG00000131023 PMC6754407__F7 Model of SHH induced increase of HELLS ENSG00000119969 ENSG00000164690 PMC7263368__F5 Representation of Yap regulation by P2y2 signaling ENSG00000150457 ENSG00000131023 PMC10995332__F5 Underlying mechanism and targeted therapy strategy of miRNAs cross-regulating EMT process through multiple signaling pathways in hepatocellular carcinoma ENSG00000169554 ENSG00000141448 ENSG00000170558 ENSG00000168036 ENSG00000120158 PMC10995332__F4 MiRNAs affect the occurrence and development of EMT in liver cancer cells by activating the TGFB signaling pathway and cross-talking multiple signaling pathways including PI3 K and MAPK ENSG00000170365 ENSG00000087245 ENSG00000137834 ENSG00000088305 ENSG00000170558 ENSG00000120693 ENSG00000185591 ENSG00000100985 ENSG00000078098 PMC6540604__F1 The deregulated metabolic pathways in AML ENSG00000135218 ENSG00000062485 ENSG00000026103 PMC8932121__F4 Inflammation in neurodegeneration: novel insights into the role of the immune system in C9orf72 HRE-mediated ALS/FTD ENSG00000183735 ENSG00000164430 ENSG00000123240 ENSG00000147894 PMC6888166__F1 Signal transduction of the unfolded protein response (UPR) ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC5340842__F1 P. infestans infection cycle and the many roles effectors play in modulating plant cellular processes ENSG00000169967 ENSG00000095015 ENSG00000169032 PMC6804972__F3 Correction: Sequential analysis of myocardial gene expression with phenotypic change: Use of cross-platform concordance to strengthen biologic relevance ENSG00000123700 ENSG00000159200 ENSG00000135547 ENSG00000118729 ENSG00000130234 ENSG00000113296 ENSG00000160808 ENSG00000120937 PMC10995332__F3 Underlying mechanism and targeted therapy strategy of miRNAs cross-regulating EMT process through multiple signaling pathways in hepatocellular carcinoma ENSG00000107562 ENSG00000170558 ENSG00000198793 PMC10995332__F2 Underlying mechanism and targeted therapy strategy of miRNAs cross-regulating EMT process through multiple signaling pathways in hepatocellular carcinoma ENSG00000087095 ENSG00000154342 ENSG00000138795 ENSG00000134982 ENSG00000136997 ENSG00000026508 ENSG00000168036 ENSG00000155760 ENSG00000125084 ENSG00000140807 PMC6901970__F1 Regulation of Tfr cell differentiation and function ENSG00000150907 ENSG00000049768 ENSG00000168610 PMC1728094__F1 The receptor for IL-6 consists of the ligand binding component (IL-6R) and the signal-transducing gp130 ENSG00000162692 ENSG00000168610 PMC11203016__F10 Illustration of the Toll-like receptor signaling and apoptosis pathways in M ENSG00000149311 ENSG00000170458 ENSG00000150455 ENSG00000127948 ENSG00000084774 PMC7225374__F11 Core apoptotic pathway and its regulation by miRNAs in THP-1 cells exposed to the lower dose of CdS QDs ENSG00000100290 ENSG00000002330 ENSG00000070831 ENSG00000168040 ENSG00000096717 ENSG00000135116 ENSG00000104081 ENSG00000185104 ENSG00000026103 PMC7940541__F7 Schematic model: the mechanisms through which huaier extract inhibits the growth of prostate cancer ENSG00000184012 ENSG00000101557 PMC8542577__F4 Atherosclerosis Pathways are Activated in Pericoronary Adipose Tissue of Patients with Coronary Artery Disease ENSG00000048162 ENSG00000172216 ENSG00000163421 ENSG00000291748 ENSG00000175592 ENSG00000167074 ENSG00000117707 ENSG00000178726 PMC8548714__F1 Current Application and Future Prospects of Astragalus Polysaccharide Combined With Cancer Immunotherapy: A Review ENSG00000178860 ENSG00000102962 ENSG00000111537 ENSG00000115415 ENSG00000047936 ENSG00000168610 PMC8542577__F3 Atherosclerosis Pathways are Activated in Pericoronary Adipose Tissue of Patients with Coronary Artery Disease ENSG00000126218 ENSG00000101981 ENSG00000117525 ENSG00000003436 ENSG00000110799 ENSG00000175899 ENSG00000088926 ENSG00000164344 ENSG00000122194 ENSG00000276838 ENSG00000178726 ENSG00000185010 PMC8546664__AF1 Alterations of DNA damage response pathway: Biomarker and therapeutic strategy for cancer immunotherapy ENSG00000149311 ENSG00000183735 ENSG00000111537 ENSG00000184995 PMC4906842__F2 Steroid biosynthesis pathway ENSG00000179142 PMC11972380__F8 Schematic diagram deciphering the mechanisms by which ROBO1, G3BP2 and eIF3A form hetero-complex to mediate radio-resistance in ESCC cells ENSG00000138757 ENSG00000198793 ENSG00000107581 PMC2996094__F11 Proposed model of GF-mediated regulation of IGFBP-3 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8005042__F7 Pyrimidine biosynthesis in the pyrimidine metabolism pathway ENSG00000102967 ENSG00000084774 PMC11628519__F3 Molecular mechanisms of the JAK-STAT pathway in CRC cell proliferation, apoptosis, migration, and invasion ENSG00000149311 ENSG00000141867 ENSG00000136997 ENSG00000168610 PMC8415165__F11 Extract of Sonneratia apetala Leaves and Branches Ameliorates Hyperuricemia in Mice by Regulating Renal Uric Acid Transporters and Suppressing the Activation of the JAK/STAT Signaling Pathway ENSG00000125538 ENSG00000168610 PMC8267717__F2 Intestinal Permeability Is a Mechanical Rheostat in the Pathogenesis of Liver Cirrhosis ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC8945898__F1 Histamine Intolerance—A Kind of Pseudoallergic Reaction ENSG00000140287 PMC4427128__F1 Coagulation and inflammatory response activation during dengue ENSG00000108691 ENSG00000003436 PMC4477307__F10 Cooperative disruption of signaling network downstream of mutated KRAS ENSG00000002330 ENSG00000156299 ENSG00000149269 ENSG00000115904 PMC2647860__F7 p53, Cyclin-dependent Kinase and Abnormal Amplification of Centrosomes ENSG00000101224 ENSG00000166851 PMC9086356__F1 Innate Lymphoid Cells in Cancer Development and Immunotherapy ENSG00000165030 ENSG00000107485 ENSG00000198846 ENSG00000112486 ENSG00000106546 PMC7265313__F9 Final scheme ENSG00000112977 ENSG00000188878 ENSG00000151466 ENSG00000110274 ENSG00000128602 PMC5817860__F3 Crosstalk between c-Met and EGFR ENSG00000002330 ENSG00000163235 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC10537261__F3 Ghrelin as a Biomarker of “Immunometabolic Depression” and Its Connection with Dysbiosis ENSG00000198576 PMC3421049__F1 Genomic Variation and Neurohormonal Intervention in Heart Failure ENSG00000179142 PMC7987467__F1 Severe SARS-CoV-2 syndrome as a result of hypoxia and HIF-1 signaling pathway activation ENSG00000108691 PMC7403780__F6 Recombination salvage pathway regulation ENSG00000132646 ENSG00000051180 PMC2929667__F6 Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation ENSG00000109819 ENSG00000112964 ENSG00000169856 ENSG00000173757 ENSG00000150907 ENSG00000169047 ENSG00000146678 ENSG00000124253 PMC8946206__F2 Angiogenesis Inhibitors and Immunomodulation in Renal Cell Cancers: The Past, Present, and Future ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC544835__F1 Reverse Cholesterol Transport ENSG00000130164 PMC6406579__F3 Current model of Cln3 function in Dictyostelium ENSG00000166340 ENSG00000261832 PMC4403904__F1 Signaling pathway mediates hepatic fibrogenesis: (A) the TGFB1/SMAD signaling pathway, and (B) TLR4 activated-MyD88/TGFB1/NFKB pathway ENSG00000172936 ENSG00000175104 PMC3681501__F5 Lin28b Promotes Head and Neck Cancer Progression via Modulation of the Insulin-Like Growth Factor Survival Pathway ENSG00000073792 ENSG00000118971 ENSG00000140443 PMC5113843__F3 Proposed metabolic role of RubisCO, with genes identified in the PER-1 (blue line) and WS6-1 genomes (purple line) ENSG00000197713 ENSG00000153574 PMC7136022__F4 PGE2 signaling pathways ENSG00000291971 PMC6650088__F2 Systematic discovery of the functional impact of somatic genome alterations in individual tumors through tumor-specific causal inference ENSG00000124102 ENSG00000143248 ENSG00000159216 ENSG00000149968 ENSG00000117400 ENSG00000133063 ENSG00000121879 PMC3726373__F5 Ribonucleotide Reductase Large Subunit M1 Predicts Poor Survival Due to Modulation of Proliferative and Invasive Ability of Gastric Cancer ENSG00000170558 ENSG00000167325 PMC6958506__F4 A summary of miR-205-5p expression regulation and direct targets of miR-205-5p and their biological effects ENSG00000126016 ENSG00000065361 ENSG00000114315 PMC8637616__F1 Neuroprotection by dipeptidyl-peptidase-4 inhibitors and glucagon-like peptide-1 analogs via the modulation of AKT-signaling pathway in Alzheimer’s disease ENSG00000198793 ENSG00000168036 PMC6164844__F2 Suggested mechanistic pathway of different flavonoids in the activation of non-shivering thermogenesis in BAT and WAT ENSG00000142611 ENSG00000096717 PMC4595741__F3 Revisiting the chlorophyll biosynthesis pathway using genome scale metabolic model of Oryza sativa japonica ENSG00000122966 ENSG00000172005 PMC4595741__F1 Revisiting the chlorophyll biosynthesis pathway using genome scale metabolic model of Oryza sativa japonica ENSG00000122966 ENSG00000172005 PMC4795655__F4 De Novo Transcriptome Analysis Provides Insights into Immune Related Genes and the RIG-I-Like Receptor Signaling Pathway in the Freshwater Planarian (Dugesia japonica) ENSG00000183735 ENSG00000107201 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000276561 PMC9575458__F2 Therapeutic Potential of miRNAs for Type 2 Diabetes Mellitus: An Overview ENSG00000171105 ENSG00000169047 PMC4808588__F4 Multifaceted biology of plasmacytoid dendritic cells ENSG00000239732 ENSG00000188313 ENSG00000139370 ENSG00000172936 ENSG00000110057 ENSG00000276561 ENSG00000138760 ENSG00000010671 PMC7243120__F1 An autoregulatory loop controls Proline biosynthesis ENSG00000128272 ENSG00000144895 ENSG00000059573 PMC4338588__F1 Hypothetical model illustrating the molecular basis of insulin-induced metabolic stress in patients with poorly controlled T2D in which both blood glucose and FFA levels are persistently elevated ENSG00000135636 ENSG00000135218 ENSG00000042832 PMC3186011__F1 Cell surface and endosomal recognition of viruses by Toll-like receptors (TLRs) ENSG00000115008 ENSG00000239732 ENSG00000125538 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC9594080__F1 Redox potential determines NSPCs fate ENSG00000149311 ENSG00000198793 ENSG00000105227 ENSG00000079999 PMC1482699__F5 GenMAPP growth hormone (Gh) signaling pathway ENSG00000120833 ENSG00000140564 ENSG00000196090 ENSG00000112964 ENSG00000221869 ENSG00000157017 ENSG00000143933 ENSG00000162999 ENSG00000245848 ENSG00000138378 ENSG00000291972 ENSG00000172216 ENSG00000173757 ENSG00000010810 ENSG00000123609 ENSG00000106070 ENSG00000180616 ENSG00000185591 ENSG00000180008 PMC5454413__F2 Proposed regulatory signaling network for HCV entry ENSG00000137834 ENSG00000130164 ENSG00000138798 ENSG00000146648 ENSG00000076662 ENSG00000204217 PMC6124548__F6 Somitogenesis and somite patterning ENSG00000164690 PMC12112207__F5 Isochlorogenic Acid C Alleviates Allergic Asthma via Interactions Between Its Bioactive Form and the Gut Microbiome ENSG00000108839 ENSG00000161905 ENSG00000275565 PMC4457157__F3 Crosstalk between growth factor and adhesion protein signaling ENSG00000291971 ENSG00000168036 PMC3651056__F2 Arachidonic acid metabolic pathways and the role of IL-13 ENSG00000226275 ENSG00000131724 PMC3308858__F8 How GSK3B phosphorylation is involved with microtubule destabilization PMC7207169__F3 MYC and the unfolded protein response in cancer: synthetic lethal partners in crime? ENSG00000178607 ENSG00000136997 ENSG00000100219 PMC7207169__F2 MYC and the unfolded protein response in cancer: synthetic lethal partners in crime? ENSG00000128272 ENSG00000144895 PMC4094593__F9 Diagram of the roles of miR-206 in hepatocellular carcinoma (HCC) HepG2 cells ENSG00000074181 ENSG00000114315 PMC8815128__F6 N6-methyladenosine-dependent modification of circGARS acts as a new player that promotes SLE progression through the NFKB/A20 axis ENSG00000101751 ENSG00000198492 ENSG00000123908 PMC3638721__F7 TRAIL-activated proapoptotic and antiapoptotic pathways ENSG00000168040 ENSG00000164305 PMC6735542__F1 SLC3A2 in regulation of autophagy activation and cell radiosensitivity ENSG00000168003 ENSG00000100473 ENSG00000151012 ENSG00000198793 ENSG00000103257 PMC3745713__F2 Methionine–homocysteine and aromatase pathways and their involvement in 2-ME synthesis ENSG00000205221 ENSG00000124275 ENSG00000116984 PMC9022112__F1 Nitric Oxide in Plant Senescence PMC8286120__F4 Goblet Cells in Intestinal Barrier and Mucosal Immunity ENSG00000137033 ENSG00000166090 ENSG00000293532 PMC8267409__F1 Targeting Long Non-Coding RNAs in Hepatocellular Carcinoma: Progress and Prospects ENSG00000168003 ENSG00000124422 ENSG00000103222 ENSG00000100744 ENSG00000096717 ENSG00000292186 ENSG00000079999 PMC9450509__F9 DDX56 inhibits PRV replication through regulation of IFNB signaling pathway by targeting cGAS ENSG00000183735 ENSG00000164430 ENSG00000136271 PMC8267409__F3 Targeting Long Non-Coding RNAs in Hepatocellular Carcinoma: Progress and Prospects ENSG00000228716 ENSG00000169554 ENSG00000171791 ENSG00000123908 PMC8333094__F9 Thioesterase induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin results in a futile cycle that inhibits hepatic Beta-oxidation ENSG00000005469 ENSG00000127884 PMC8267409__F2 Targeting Long Non-Coding RNAs in Hepatocellular Carcinoma: Progress and Prospects ENSG00000124422 ENSG00000169554 ENSG00000060491 ENSG00000198793 ENSG00000144848 ENSG00000096717 ENSG00000168610 ENSG00000132819 PMC4629213__F1 Bile acid synthesis and metabolism ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC8267409__F4 Targeting Long Non-Coding RNAs in Hepatocellular Carcinoma: Progress and Prospects ENSG00000119888 ENSG00000198793 ENSG00000168610 PMC3285581__F7 Msx Homeobox Genes Critically Regulate Embryo Implantation by Controlling Paracrine Signaling between Uterine Stroma and Epithelium ENSG00000120149 ENSG00000168036 ENSG00000163132 PMC5739690__F8 Insulin receptor substrate-4 interacts with ubiquitin-specific protease 18 to activate the Jak/STAT signaling pathway ENSG00000184979 ENSG00000213928 ENSG00000105397 PMC7432461__F3 Interactions of coronavirus proteins with metabolic pathways ENSG00000130414 ENSG00000120697 ENSG00000146143 ENSG00000198056 ENSG00000136888 ENSG00000095380 ENSG00000158125 ENSG00000179958 ENSG00000101868 ENSG00000117054 ENSG00000074800 ENSG00000131238 ENSG00000072210 ENSG00000014138 ENSG00000197858 ENSG00000123983 ENSG00000089597 ENSG00000180185 ENSG00000178035 ENSG00000132793 ENSG00000108515 ENSG00000147684 ENSG00000136877 ENSG00000018510 ENSG00000196839 ENSG00000133835 ENSG00000114573 ENSG00000165282 ENSG00000105223 ENSG00000159921 ENSG00000033100 ENSG00000253710 ENSG00000185813 ENSG00000001630 ENSG00000100596 ENSG00000123989 ENSG00000156110 ENSG00000100330 ENSG00000259431 ENSG00000186010 ENSG00000159063 ENSG00000163527 ENSG00000171848 ENSG00000197142 ENSG00000047315 ENSG00000073737 PMC11817190__F3 Influence of micronutrients on bone metabolism ENSG00000178860 ENSG00000152266 ENSG00000167941 PMC5753398__F1 Hedgehog signaling pathway ENSG00000106571 ENSG00000164161 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC2613930__F4 Genes that contain the 100 most differentially methylated CpG sites between normal and lung cancer tissue samples (p-value < 0.005) ENSG00000198681 ENSG00000005073 ENSG00000172680 ENSG00000277586 ENSG00000078900 ENSG00000166573 ENSG00000164362 ENSG00000115138 ENSG00000129152 ENSG00000001626 ENSG00000181195 ENSG00000102468 PMC7662392__F2 Potential mechanisms for KSHV manipulating IL-1 signaling pathway ENSG00000115602 ENSG00000137033 ENSG00000136696 ENSG00000136694 ENSG00000134070 ENSG00000172936 ENSG00000184216 ENSG00000115594 ENSG00000115607 PMC9599057__F3 Rosmarinic Acid and Related Dietary Supplements: Potential Applications in the Prevention and Treatment of Cancer ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000168040 PMC5943638__F1 Metformin as a Tool to Target Aging ENSG00000171105 ENSG00000169047 ENSG00000198793 ENSG00000096717 PMC11743488__F1 TGFB pathway signaling in MFS PMC9319879__F2 Crucial Role of Oncogenic KRAS Mutations in Apoptosis and Autophagy Regulation: Therapeutic Implications ENSG00000068028 ENSG00000159224 ENSG00000002330 ENSG00000156299 PMC5648141__F10 Inferring gene and protein interactions using PubMed citations and consensus Bayesian networks ENSG00000213928 ENSG00000198793 ENSG00000131095 ENSG00000198626 PMC5580487__F2 Pro-apoptotic role of HBV ENSG00000120868 ENSG00000168040 ENSG00000026103 PMC9319879__F1 Crucial Role of Oncogenic KRAS Mutations in Apoptosis and Autophagy Regulation: Therapeutic Implications ENSG00000159224 ENSG00000156299 ENSG00000198793 PMC10985007__F1 HIFs and NRF2, adaptive response systems to variable oxygen availability ENSG00000134086 ENSG00000100387 PMC5580487__F1 Inhibition of apoptosis by hepatitis B Virus (HBV) infection ENSG00000104856 ENSG00000002330 ENSG00000102871 ENSG00000291971 ENSG00000123454 ENSG00000177606 ENSG00000162924 ENSG00000120868 ENSG00000168040 ENSG00000127191 PMC3510514__F6 Model for the role of Spartan in DNA damage tolerance ENSG00000132646 ENSG00000162607 ENSG00000070950 PMC8718907__F2 Distinct Roles of Sialyltransferases in Cancer Biology and Onco-Immunology ENSG00000159921 ENSG00000170191 ENSG00000162139 ENSG00000111726 ENSG00000164414 ENSG00000115488 ENSG00000119899 ENSG00000095380 PMC4303658__F1 Thymidine metabolism in the cytosol and mitochondrial matrix ENSG00000228716 ENSG00000158825 PMC5302999__F2 Progress and perspective of TBX6 gene in congenital vertebral malformations ENSG00000154342 ENSG00000179111 ENSG00000188095 ENSG00000149922 PMC6733361__F1 The potential molecular pathways representing potential targets for treatment in patients with ACC, based on the results presented in the current review ENSG00000197081 ENSG00000135446 ENSG00000169047 ENSG00000105810 ENSG00000140443 PMC3653416__F2 Autophagy in alcohol-induced liver diseases ENSG00000177169 ENSG00000198793 ENSG00000130649 PMC6651518__F10 Mutual interactions of expression of the genes examined with qPCR and shown in , and ENSG00000053747 ENSG00000169429 ENSG00000137076 ENSG00000101162 ENSG00000112715 ENSG00000101680 PMC9388619__F2 Canonical G1/S pathway ENSG00000015285 ENSG00000139687 PMC6353800__F1 Schematic overview of major enzymes and metabolites involved in the regulation of gluconeogenesis ENSG00000042832 ENSG00000173599 PMC2515553__F1 Ischemic Preconditioning And Myocardial Infarction: An Update and Perspective ENSG00000182533 ENSG00000115415 ENSG00000291971 ENSG00000168610 PMC5055986__F7 A probable signaling pathway of folic acid mediated modulation of inflammatory response in microglia cells PMC7867260__F3 Gluconeogenesis and other rescue pathways for the generation of metabolic intermediates in low-glucose conditions ENSG00000124253 PMC4252877__F4 Embryonic development, organ development, organ morphology, cellular growth and proliferation, cancer, and tumor morphology ENSG00000160194 ENSG00000111057 ENSG00000091972 ENSG00000109321 ENSG00000018510 ENSG00000198648 ENSG00000186998 ENSG00000005102 ENSG00000129514 PMC6353800__F4 Hepatic gluconeogenesis is modulated by histone deacetylases (HDACs) ENSG00000094631 ENSG00000171720 ENSG00000288269 ENSG00000150907 ENSG00000160741 ENSG00000069667 PMC7867260__F2 Biosynthetic pathways branching from glycolysis in glucose-replete conditions ENSG00000115419 ENSG00000159399 PMC11662784__F5 DEAD-Box Helicases in Colorectal Cancer: DDX27: DDX27 promotes the gene expression of known CSC markers (CD44, CD133, EpCAM, LGR5), stabilizing the self-renewal phenotype of CRC cells and contributing to tumor initiation and development ENSG00000103266 ENSG00000119888 ENSG00000136271 ENSG00000145833 ENSG00000124228 ENSG00000026508 ENSG00000105810 PMC11662784__F4 DEAD-Box Helicases in Colorectal Cancer: DDX3: DDX3 enhances the transcription of KRAS by increasing the binding of SP1 to the KRAS promoter, leading to increased KRAS expression and activation of the PI3K/AKT pathway ENSG00000004975 ENSG00000181163 ENSG00000198793 ENSG00000071967 ENSG00000124228 ENSG00000168036 ENSG00000108654 ENSG00000185591 ENSG00000136942 ENSG00000178105 ENSG00000196363 PMC11662784__F3 DEAD-Box Helicases in Gastric Cancer: DDX5: DDX5 increases the expression of p-mTOR and p-S6K1, promoting the growth of gastric cancer ENSG00000150907 ENSG00000198793 ENSG00000145833 ENSG00000124228 ENSG00000108654 ENSG00000123374 ENSG00000089737 ENSG00000113360 PMC11662784__F2 DEAD-Box Helicases in Esophageal Cancer: DDX5: DDX5 enhances the expression of CDK2 and Cyclin D1, promoting the G1/S phase transition in esophageal cancer cells ENSG00000198793 ENSG00000145833 ENSG00000288503 ENSG00000168036 ENSG00000108654 ENSG00000123374 PMC6405391__F1 Energy imbalance leads to obesity ENSG00000042832 PMC3941025__F1 MAVS filaments and activation of the IFN-I pathway ENSG00000088888 ENSG00000276561 PMC5510910__F9 Dectin-2 is a primary receptor for NLRP3 inflammasome activation in dendritic cell response to Histoplasma capsulatum ENSG00000162711 ENSG00000125538 PMC4014927__F2 Summary of statin‐mediated peroxisome proliferator‐activated receptor G (PPARG) activation in macrophages ENSG00000070831 ENSG00000163914 PMC12230643__F4 Multi‐omics network of hyperglycemia‐induced vascular calcification ENSG00000125166 ENSG00000177674 ENSG00000154310 PMC10341911__F3 Syntenic analysis of genes in the Moso bamboo and rice cytokinin pathway families PMC5448611__F9 PPI network of new predicted LUAD-related genes ENSG00000163637 ENSG00000100234 ENSG00000138639 ENSG00000135218 ENSG00000145147 ENSG00000184347 ENSG00000130522 ENSG00000077522 ENSG00000140044 ENSG00000133121 ENSG00000136826 ENSG00000196628 ENSG00000151702 ENSG00000186340 ENSG00000082175 ENSG00000148773 ENSG00000154721 ENSG00000027075 ENSG00000135604 ENSG00000197471 ENSG00000174804 ENSG00000176014 ENSG00000101811 ENSG00000291606 ENSG00000204217 ENSG00000120334 ENSG00000136205 PMC5933117__F6 Model of rRNA biogenesis in rice ENSG00000101751 ENSG00000166278 PMC4700483__F5 MYC splicing connections in cancer ENSG00000011304 ENSG00000136997 PMC4467525__F5 Summary of altered glucose metabolism in MCF10A-ras cells PMC7183504__F2 Key interactions of BMX and its pathways ENSG00000008710 ENSG00000115415 ENSG00000149269 ENSG00000137193 ENSG00000074966 ENSG00000113263 ENSG00000102010 ENSG00000168610 ENSG00000135605 ENSG00000010671 PMC4052589__F1 Possible mechanisms of the opioid receptor–mediated influence of morphine on tumor growth ENSG00000172680 ENSG00000002330 ENSG00000291971 ENSG00000138798 PMC4515825__F9 Molecular mechanisms of the non-coenzyme action of thiamin in brain: biochemical, structural and pathway analysis ENSG00000146701 PMC5039670__F3 Single-cell SNP analyses and interpretations based on RNA-Seq data for colon cancer research ENSG00000137834 ENSG00000156574 ENSG00000134363 ENSG00000067900 ENSG00000205250 ENSG00000137801 ENSG00000111537 ENSG00000095739 ENSG00000100387 ENSG00000198742 ENSG00000113558 ENSG00000164093 ENSG00000185591 PMC9612132__F2 Heparin and Heparin-Based Drug Delivery Systems: Pleiotropic Molecular Effects at Multiple Drug Resistance of Osteosarcoma and Immune Cells ENSG00000148400 ENSG00000291971 ENSG00000169047 ENSG00000103222 ENSG00000168036 ENSG00000124574 ENSG00000118777 ENSG00000168610 PMC9302595__F2 Extracellular signals activate the intracellular signaling pathway mTOR ENSG00000105894 ENSG00000066468 ENSG00000108231 ENSG00000119383 PMC6000924__F2 Summary of the putative mechanisms of mutations in the LRRK2 ROCO domain ENSG00000116688 ENSG00000069329 ENSG00000171109 PMC4923873__F1 Plasma proteomic analysis of stable coronary artery disease indicates impairment of reverse cholesterol pathway ENSG00000260428 ENSG00000084774 PMC7598260__F7 Visual representation generated by MetScape (CREGN) application of the Urea cycle and metabolism of arginine, proline, glutamate, aspartate and asparagine, a common pathway among the three species ENSG00000211445 ENSG00000121552 ENSG00000081181 ENSG00000198704 ENSG00000095059 ENSG00000167468 ENSG00000118520 ENSG00000132744 ENSG00000116157 ENSG00000116649 ENSG00000070669 ENSG00000102172 PMC4852766__F6 Proposed models that potentially link collagen VI myopathy and circadian genes ENSG00000126775 ENSG00000198793 PMC5039670__F4 Single-cell SNP analyses and interpretations based on RNA-Seq data for colon cancer research ENSG00000132906 ENSG00000198793 ENSG00000196470 ENSG00000164305 ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000136997 ENSG00000123374 ENSG00000112378 ENSG00000105810 ENSG00000064012 ENSG00000026103 PMC9302595__F1 ET-1 signaling in OPCs ENSG00000169840 ENSG00000136160 ENSG00000146648 ENSG00000111962 PMC4538650__F2 Schematic of TRIM21 antiviral mechanism ENSG00000132109 ENSG00000183735 ENSG00000104343 ENSG00000107201 PMC5713369__F5 Proposed mechanism whereby SM70EE ameliorates learning and memory impairments in mice with an intracerebroventricular injection of amyloidB 1–42 (AB1–42) ENSG00000142192 PMC10137601__F7 Working model illustrating the mechanism that underlies the role of RA in regulating LH-induced oocyte meiotic resumption ENSG00000138207 ENSG00000128016 ENSG00000109321 ENSG00000124882 ENSG00000172572 ENSG00000173786 ENSG00000159899 ENSG00000146648 PMC8120225__F3 MicroRNAs in the osteogenic and chondrogenic differentiation of mesenchymal stem cells and bone pathologies ENSG00000170365 PMC3697968__F5 Model of DAF-2/IGFR pathway regulation by DPY-21 PMC6651415__F5 Possible mode of cell death pathway in Caco-2 cells ENSG00000139193 ENSG00000100290 ENSG00000137875 ENSG00000258643 ENSG00000026103 PMC7462863__F6 Genomic landscape of Mongolian hepatocellular carcinoma ENSG00000157404 ENSG00000121904 ENSG00000134982 ENSG00000197969 ENSG00000168036 ENSG00000141564 ENSG00000104332 ENSG00000174428 ENSG00000121879 ENSG00000163631 ENSG00000184675 ENSG00000004455 ENSG00000136997 ENSG00000189266 ENSG00000174197 ENSG00000108788 ENSG00000139687 ENSG00000169851 ENSG00000164796 ENSG00000106829 ENSG00000149311 ENSG00000066468 ENSG00000186472 ENSG00000134853 ENSG00000163554 ENSG00000178568 ENSG00000198625 PMC7114592__F2 Role of MNK1 in viral mRNA translation ENSG00000101425 PMC4843955__F1 Signalling and muscle proteins synthesis (MPS) responses induced by amino acids (AAs) and different contraction intensities ENSG00000198793 ENSG00000167658 PMC2474943__F7 Points of action of flavonoids within PI3K/Akt signalling pathway ENSG00000002330 ENSG00000005882 ENSG00000198793 PMC6291580__F1 Genetic determinants of cardiovascular risk in SLE ENSG00000138378 ENSG00000224320 ENSG00000111537 ENSG00000140968 ENSG00000142224 ENSG00000151327 PMC2474943__F5 Points of action of flavonoids within p38 pathway PMC2474943__F4 Points of action of flavonoids within JNK pathway ENSG00000284774 PMC7031694__F2 Ionic versus signaling pathways for cardiotonic steroid effects ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC3351101__F2 Regulation of cytoplasmic mRNA decay ENSG00000162385 ENSG00000070756 ENSG00000163435 ENSG00000100836 ENSG00000282825 PMC9411277__F4 Targeting of the tumor immune microenvironment by metformin PMC8109080__F9 Mechanistic schematic diagram showing Compound 3C alleviates atherosclerosis by multiple mechanisms ENSG00000042832 ENSG00000115415 PMC4399077__F5 Canonical and noncanonical Sap-induced inflammasome activation ENSG00000162711 ENSG00000125538 ENSG00000142166 PMC8379419__F2 Arginine metabolism and its functions in growth, nutrient utilization, and immunonutrition of fish ENSG00000081181 ENSG00000177058 ENSG00000118520 PMC5925453__F7 Common Co-activation of AXL and CDCP1 in EGFR-mutation-positive Non-Small Cell Lung Cancer Associated With Poor Prognosis ENSG00000019991 ENSG00000142627 ENSG00000065361 ENSG00000109321 ENSG00000291971 ENSG00000138798 ENSG00000144560 ENSG00000198793 ENSG00000163814 ENSG00000150457 ENSG00000131023 ENSG00000168610 ENSG00000089159 ENSG00000146648 PMC7377265__F7 Proposed Model Illustrating the Role of GABA and GABAB1R in PTGs ENSG00000152266 ENSG00000036828 PMC6525564__F4 Adrenal C19 steroid pathway ENSG00000203859 ENSG00000176387 PMC4541793__F1 ANTI-TGF-ß THERAPY IN FIBROSIS: RECENT PROGRESS AND IMPLICATIONS FOR SYSTEMIC SCLEROSIS ENSG00000132478 PMC9378677__F8 Schematic view of cell death signaling induced by 5’-ppp-RNA, cytosolic dsRNA, and extracellular dsRNA ENSG00000132906 ENSG00000168040 ENSG00000064012 ENSG00000164342 PMC9024684__F2 Protein Tyrosine Phosphatase Receptor Type Z in Central Nervous System Disease ENSG00000105894 ENSG00000157368 ENSG00000010810 ENSG00000168036 PMC5748797__F1 Formation of resveratrol metabolites by various UDP-glucuronosyltransferases (UGTs) and cytosolic sulfotransferases (SULTs) in humans ENSG00000196502 ENSG00000197165 PMC6874786__F1 PI3K/AKT/mTOR pathway in AML ENSG00000145782 ENSG00000168610 ENSG00000057663 PMC7647985__F4 ERK5 regulates the FAK signaling ENSG00000259207 ENSG00000100906 ENSG00000158195 ENSG00000163914 ENSG00000150093 ENSG00000088538 ENSG00000112715 PMC6592856__F3 Hippo signalling pathway: key components and regulatory mechanisms ENSG00000186575 ENSG00000291442 PMC7738833__F8 Hypothetical model illustrating that ALKAL1 plays an important role in colorectal cancer migration and invasion via activating SHH signaling pathway ENSG00000106683 ENSG00000149968 ENSG00000067900 ENSG00000196711 ENSG00000164690 ENSG00000100985 ENSG00000128602 PMC3765338__F3 Altered CREB/E2F1 signalling networks in co-treated HMCs ENSG00000107562 ENSG00000148926 ENSG00000163565 ENSG00000072274 ENSG00000170558 ENSG00000122877 ENSG00000163064 ENSG00000164104 ENSG00000157557 ENSG00000130164 ENSG00000122565 ENSG00000022267 ENSG00000283060 ENSG00000139687 ENSG00000125968 ENSG00000165891 ENSG00000131747 ENSG00000116741 ENSG00000163453 ENSG00000221869 ENSG00000099194 ENSG00000132170 ENSG00000133216 ENSG00000178919 ENSG00000157766 ENSG00000134853 ENSG00000114166 PMC5908807__F2 YAP is at the epicenter of a signaling network ENSG00000129474 ENSG00000109321 ENSG00000138798 ENSG00000113070 ENSG00000175592 ENSG00000087586 ENSG00000164171 ENSG00000102854 ENSG00000092820 ENSG00000127129 ENSG00000137807 ENSG00000120742 ENSG00000115457 ENSG00000163235 ENSG00000171848 ENSG00000105810 ENSG00000138271 ENSG00000146648 ENSG00000138180 PMC11680093__F5 Induced Pluripotent Stem Cells in Birds: Opportunities and Challenges for Science and Agriculture ENSG00000170365 ENSG00000096088 PMC7831924__F2 Modulations of Hippo signaling in gliomas ENSG00000044090 ENSG00000069869 ENSG00000133937 ENSG00000198793 ENSG00000263528 ENSG00000168036 ENSG00000048052 ENSG00000150457 ENSG00000146648 ENSG00000114019 ENSG00000131023 PMC9426031__F7 Glioblastoma CD105+ cells define a SOX2− cancer stem cell-like subpopulation in the pre-invasive niche ENSG00000178860 ENSG00000125285 ENSG00000105656 PMC5908807__F1 Hippo signaling and YAP phosphorylation and translocation ENSG00000150457 ENSG00000047849 ENSG00000131023 PMC4166351__F1 AB production and removal from the brain ENSG00000142192 ENSG00000119912 PMC7831924__F1 Canonical Hippo signaling pathway in mammals ENSG00000167601 ENSG00000089685 ENSG00000136997 ENSG00000197905 ENSG00000007866 ENSG00000164690 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC5908807__F4 YAP signaling is associated with unfavorable prognosis for PDAC ENSG00000129474 ENSG00000109321 ENSG00000113070 ENSG00000175592 ENSG00000087586 ENSG00000164171 ENSG00000102854 ENSG00000092820 ENSG00000127129 ENSG00000137807 ENSG00000120742 ENSG00000115457 ENSG00000163235 ENSG00000171848 ENSG00000105810 ENSG00000138271 ENSG00000146648 ENSG00000138180 PMC11680093__F6 Induced Pluripotent Stem Cells in Birds: Opportunities and Challenges for Science and Agriculture ENSG00000002330 ENSG00000198793 ENSG00000164327 PMC4956935__F2 Proposed IGF‐interaction with PPAR‐G signalling in CVD epigenetics ENSG00000198793 PMC3882377__F6 Schema of our hypothesis ENSG00000135218 ENSG00000164690 ENSG00000128602 PMC5895694__F1 Cross talk between CEA, TGFB signaling, and IL6-STAT3 pathway ENSG00000168610 PMC4546315__F1 The insulin/IGF1R signalling pathway ENSG00000169047 ENSG00000140443 PMC4356074__F3 Canonical and non-canonical Wnt signaling pathways ENSG00000134982 PMC4070521__F1 Biosynthetic pathway of n3 and n6 PUFAs highlighting a set of genes known to play key roles in the biosynthesis and metabolism of LC-PUFAs in two parallel and competing pathways ENSG00000134824 ENSG00000149485 PMC6475556__F7 The mechanisms of total triterpenes of the E ENSG00000181019 ENSG00000136869 PMC4103158__F3 Proteomic Analysis of Lysine Acetylation Sites in Rat Tissues Reveals Organ Specificity and Subcellular Patterns ENSG00000159173 ENSG00000168530 ENSG00000133020 ENSG00000143549 ENSG00000198336 ENSG00000171503 ENSG00000073578 ENSG00000077522 ENSG00000117118 ENSG00000101470 ENSG00000163541 ENSG00000288219 ENSG00000197616 ENSG00000140416 ENSG00000288250 ENSG00000100412 ENSG00000137992 ENSG00000160808 ENSG00000146701 ENSG00000128928 ENSG00000091140 ENSG00000117305 ENSG00000198947 ENSG00000062485 PMC8275185__F8 Transcriptome Analysis of Chloris virgata, Which Shows the Fastest Germination and Growth in the Major Mongolian Grassland Plant ENSG00000108582 ENSG00000110934 PMC6599049__F6 Proposed mechanism for antiviral activity of manassantin B toward coxsackievirus B3 ENSG00000183735 ENSG00000164430 PMC11989106__F1 MTOR signaling pathway: The mTOR signaling network consists of two branches, each mediated by a specific complex, mTORC1 and mTORC2 ENSG00000155506 ENSG00000155792 PMC4248024__F1 The NAD pathway model ENSG00000291814 ENSG00000123572 ENSG00000278488 ENSG00000008130 ENSG00000227345 PMC6356085__F6 Network analysis identified RABEP2 as an important protein in inflammatory and signaling pathways implication in the development of inflammation and cancer ENSG00000140319 ENSG00000154553 ENSG00000291971 ENSG00000071082 ENSG00000115339 ENSG00000213341 ENSG00000092929 ENSG00000100442 ENSG00000177548 ENSG00000102172 ENSG00000174444 PMC9284958__F1 Comprehensive network map of IL-17A signaling pathway ENSG00000115415 ENSG00000173039 ENSG00000128342 PMC9170606__F2 Twists and turns of the genetic story of mevalonate kinase-associated diseases: A review ENSG00000160752 ENSG00000110921 ENSG00000167508 PMC10742340__F1 Molecular signaling pathways associated with Mn neurotoxicity ENSG00000162711 ENSG00000150782 ENSG00000164430 ENSG00000144895 ENSG00000158828 ENSG00000096717 ENSG00000168610 PMC5722193__F2 Acute metabolic effects of AMPK activation ENSG00000135218 ENSG00000198793 PMC5207000__F2 Genetically decreased vitamin D and risk of Alzheimer disease ENSG00000111012 ENSG00000172893 ENSG00000019186 ENSG00000145321 ENSG00000186104 PMC8553772__F7 Schematic demonstrating p32 regulates melanoma via AKT/PKB signaling ENSG00000170558 ENSG00000100985 PMC7379631__F3 UPR disease biomarkers and therapeutic targets ENSG00000100811 ENSG00000100220 ENSG00000065485 ENSG00000128272 ENSG00000144895 ENSG00000150907 ENSG00000060566 ENSG00000127191 ENSG00000198911 PMC4593375__F1 The primary epidermal growth factor receptor (EGFR) signaling pathway ENSG00000198793 ENSG00000146648 PMC10894836__F4 MiRNAs in Müller cells on retinal regeneration ENSG00000144579 ENSG00000131914 ENSG00000105392 ENSG00000050165 ENSG00000150093 ENSG00000136826 ENSG00000140416 PMC10894836__F2 MiRNAs on gliogenesis ENSG00000112576 ENSG00000125398 ENSG00000074181 PMC11234281__F2 Piezo1 located in different cells regulates bone formation ENSG00000164761 ENSG00000198793 ENSG00000020633 ENSG00000129226 ENSG00000168036 ENSG00000067900 ENSG00000112715 ENSG00000137801 ENSG00000288499 ENSG00000074181 ENSG00000167941 ENSG00000152592 ENSG00000172936 ENSG00000131196 ENSG00000103335 PMC3238182__F1 Involvement of miR-221/222 as downstream effectors of the EGFR-RAS-RAF-MEK pathway in progression of metastatic transformation of breast cancer tumors ENSG00000169554 ENSG00000138798 ENSG00000175592 ENSG00000104447 ENSG00000146648 PMC8425390__F3 Reusability and composability in process description maps: RAS–RAF–MEK–ERK signalling ENSG00000157764 PMC5801557__F1 Parathyroid tumorigenesis mechanisms via the cyclins pathway ENSG00000133895 ENSG00000134371 PMC8425390__F1 Reusability and composability in process description maps: RAS–RAF–MEK–ERK signalling ENSG00000002330 ENSG00000171791 ENSG00000146648 PMC3116046__F2 Increased expression of DNA repair genes in invasive human pancreatic cancer cells ENSG00000187741 ENSG00000112039 ENSG00000158169 ENSG00000139618 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000111537 ENSG00000144554 ENSG00000051180 ENSG00000095002 ENSG00000123268 ENSG00000156273 PMC5369312__F4 Pediatric Ependymoma: A Proteomics Perspective ENSG00000074800 ENSG00000134308 ENSG00000175592 ENSG00000189403 ENSG00000127022 ENSG00000185591 ENSG00000231925 ENSG00000005381 ENSG00000130513 PMC7519545__F1 ABCA1 cell signaling pathways ENSG00000153208 ENSG00000172936 ENSG00000136869 PMC5822899__F2 Drugs Involved in Dyslipidemia and Obesity Treatment: Focus on Adipose Tissue ENSG00000111537 ENSG00000162692 PMC5822899__F1 The main intracellular pathways and the effects of drugs used in dyslipidemia and obesity in (A) differentiation of preadipocytes into mature adipocytes ENSG00000135218 ENSG00000042832 ENSG00000145321 PMC7044792__F1 Extrinsic pathway of apoptosis ENSG00000102871 ENSG00000168040 PMC7044792__F4 HIV-1 and necroptosis ENSG00000150782 ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC8632052__F5 Chronic Circadian Rhythm Disturbance Accelerates Knee Cartilage Degeneration in Rats Accompanied by the Activation of the Canonical Wnt/Beta-Catenin Signaling Pathway ENSG00000125538 ENSG00000168036 PMC4694980__F4 Core of kinase-regulated interactomes defines the neoplastic MDSC lineage ENSG00000147649 ENSG00000181163 ENSG00000117118 ENSG00000122565 PMC8707860__F7 VEGFB Promotes Myoblasts Proliferation and Differentiation through VEGFR1-PI3K/Akt Signaling Pathway ENSG00000122180 ENSG00000132646 ENSG00000198793 PMC4694980__F6 A core of kinase-regulated interactomes defines the neoplastic MDSC lineage ENSG00000123144 ENSG00000196975 ENSG00000198125 PMC4694980__F3 A core of kinase-regulated interactomes defines the neoplastic MDSC lineage ENSG00000163956 ENSG00000165119 ENSG00000175220 ENSG00000130402 ENSG00000176788 PMC4694980__F2 A core of kinase-regulated interactomes defines the neoplastic MDSC lineage ENSG00000124570 ENSG00000130414 ENSG00000198125 PMC4142901__F1 Hh signalling and cancer: Growth factors can increase the concentration of ligand which prevents the inhibitory effect of PTCH ENSG00000106571 ENSG00000120149 ENSG00000166813 ENSG00000164690 ENSG00000171791 ENSG00000139549 ENSG00000163501 PMC2892843__F3 Dual MAG receptor model ENSG00000169783 PMC8042594__F1 Monocytic and macrophage contribution to SARS-CoV-2 hyperinflammation ENSG00000130234 ENSG00000125538 ENSG00000168610 PMC9499417__F1 IL-7 and IL-7R in Cancer Pathophysiology and Immunotherapy ENSG00000002330 ENSG00000115415 ENSG00000198793 ENSG00000171791 ENSG00000105639 ENSG00000168610 PMC10489547__F3 Main signaling pathway of cell division cycle 20 homologue (CDC20) in cancers ENSG00000154342 ENSG00000137804 ENSG00000134086 ENSG00000116691 ENSG00000134057 ENSG00000176248 ENSG00000101057 ENSG00000168610 ENSG00000117399 ENSG00000108106 ENSG00000125084 PMC4999903__F8 Sinularin-induced apoptosis in the AGS and NCI-N87 gastric cancer cells ENSG00000002330 ENSG00000198793 PMC8595028__F1 Rh-CXCL-12 Attenuates Neuronal Pyroptosis after Subarachnoid Hemorrhage in Rats via Regulating the CXCR4/NLRP1 Pathway ENSG00000107562 ENSG00000091592 ENSG00000121966 PMC9072740__F4 Relationship of Redox With Hallmarks of Cancer: The Importance of Homeostasis and Context ENSG00000168003 ENSG00000167468 ENSG00000111684 ENSG00000042286 PMC6054262__F1 O-GlcNAcylation regulates oxidative stress signaling pathways ENSG00000170899 ENSG00000151012 ENSG00000198408 ENSG00000173039 ENSG00000184481 ENSG00000023909 ENSG00000079999 ENSG00000065833 ENSG00000134086 ENSG00000181019 ENSG00000150907 ENSG00000284099 ENSG00000167996 ENSG00000198074 PMC8185510__F6 Autophagy inhibition and microRNA-199a-5p upregulation in paclitaxel-resistant A549/T lung cancer cells ENSG00000198793 ENSG00000284161 ENSG00000057663 PMC9103474__F2 Oral Microbiota-Driven Cell Migration in Carcinogenesis and Metastasis ENSG00000087095 ENSG00000169554 ENSG00000102837 ENSG00000138798 ENSG00000102760 ENSG00000168036 ENSG00000168610 PMC3429622__F4 TRBP in the exogenous and endogenous RNAi pathways ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC4001781__F3 Acquired and intrinsic BRAF inhibitor resistance in BRAF V600E mutant melanoma ENSG00000157764 PMC4909198__F7 Transcriptome Sequencing and Analysis for Culm Elongation of the World’s Largest Bamboo (Dendrocalamus sinicus) ENSG00000084774 PMC5354844__F5 The function of cancer-shed gangliosides in macrophage phenotype: involvement with angiogenesis ENSG00000118520 ENSG00000121807 ENSG00000105639 PMC3166354__F1 Cellular and Molecular Action of the Mitogenic Protein-Deamidating Toxin from Pasteurella multocida ENSG00000245848 ENSG00000070831 ENSG00000148400 ENSG00000137193 ENSG00000168036 ENSG00000182621 ENSG00000146648 PMC3288643__F1 Ephs and Ephrins in Cancer: Ephrin-A1 Signaling ENSG00000142627 PMC8060460__F1 Process of neddylation modification of proteins ENSG00000198742 ENSG00000144744 ENSG00000159593 ENSG00000184182 ENSG00000146648 PMC9035666__F4 Dan-Shen-Yin Granules Prevent Hypoxia-Induced Pulmonary Hypertension via STAT3/HIF-1A/VEGF and FAK/AKT Signaling Pathways ENSG00000291971 ENSG00000177606 ENSG00000136997 ENSG00000173039 ENSG00000121879 ENSG00000168610 PMC3533463__F1 Biosynthesis pathways of phospholipid components in archaea ENSG00000110921 ENSG00000159224 ENSG00000148377 PMC3882864__F1 The variety of stimuli that can up-regulate NKG2D and DNAM-1 ligands ENSG00000149311 ENSG00000175054 ENSG00000231179 ENSG00000204520 PMC7914548__F2 Host mucosal responses to C ENSG00000143546 ENSG00000115009 PMC3937043__F5 Ingenuity Pathway Analysis (IPA) of the 39 differentially expressed genes in MFG transcriptome at 18 hpi vs ENSG00000128016 ENSG00000101160 ENSG00000140379 ENSG00000125538 ENSG00000116717 PMC2698645__F1 Simplified schematic representation of the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway driven by muscle contraction, insulin, essential amino acids (leucine), and/or energy ENSG00000011566 ENSG00000284161 ENSG00000167658 PMC6220322__F8 Metabolic enzymes that characterize the progression from a normal liver to cirrhosis, which culminates in HCC ENSG00000128609 ENSG00000117118 ENSG00000178741 ENSG00000156467 ENSG00000136872 ENSG00000131828 ENSG00000159399 PMC2698645__F2 Simplified schematic representation of the interaction between the mTORC1 and ERK1/2 signaling pathways following muscle contraction and/or insulin stimulation ENSG00000284161 ENSG00000167658 PMC8818599__F7 Sepsis induces interleukin 6, gp130/JAK2/STAT3, and muscle wasting ENSG00000169047 ENSG00000168610 PMC7904555__F2 Intracellular trafficking pathways of TLR4 and TRAM ENSG00000291873 ENSG00000136869 ENSG00000165527 ENSG00000184056 ENSG00000143669 PMC7904555__F1 Pro-inflammatory signaling pathways of TLR4 ENSG00000162711 ENSG00000170458 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 PMC5061788__F1 mTOR signalling pathway ENSG00000198793 ENSG00000164327 PMC4171604__F8 Anti-neoplastic properties of hydralazine in prostate cancer ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC2702500__F1 Metabolic reconstruction of Db ENSG00000166278 ENSG00000094975 PMC7352732__F2 Ferroptosis is the result of an accumulation of lipid reactive species ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000100033 ENSG00000198363 PMC7671541__F6 ED-71 inhibiting NLRP3 inflammasome-dependent pyroptosis in HGFs ENSG00000278718 ENSG00000162711 ENSG00000136869 PMC8511224__F2 WNT4 signaling pathway ENSG00000169071 ENSG00000100592 ENSG00000134982 ENSG00000177606 ENSG00000168036 ENSG00000146122 ENSG00000132478 PMC9102468__F1 LINC00665: An Emerging Biomarker for Cancer Diagnostics and Therapeutics ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198074 ENSG00000168036 ENSG00000185591 ENSG00000063244 ENSG00000146648 ENSG00000163507 PMC7018995__F3 Correlation of molecular mechanisms in CTCL and NSCLC and corresponding simulation results ENSG00000149311 ENSG00000168283 ENSG00000171791 PMC6405444__F2 Major pathways converging on uncontrolled growth in Drosophila epithelial cells ENSG00000136997 PMC7913953__F3 Over- and under-expressed genes are enriched in the human cell cycle pathway ENSG00000145604 ENSG00000094804 ENSG00000118007 ENSG00000101972 ENSG00000108055 ENSG00000132646 ENSG00000123374 ENSG00000277273 ENSG00000166851 ENSG00000117399 ENSG00000276876 PMC7352732__F4 K-ras transcription regulation roadmap ENSG00000083093 ENSG00000151012 ENSG00000142178 ENSG00000198793 ENSG00000110931 ENSG00000181690 ENSG00000162772 ENSG00000160741 ENSG00000079999 ENSG00000168003 ENSG00000074800 ENSG00000128272 ENSG00000160584 ENSG00000167468 ENSG00000156273 PMC5817859__F2 Alternative downstream compounds-induced EGFR-TKIs resistance ENSG00000198793 ENSG00000146648 PMC3834200__F7 MEK/ERK signaling directly and indirectly contributes to the cyclical self-renewal of spermatogonial stem cells ENSG00000146857 PMC4946798__F2 Probing the complexities of astrocyte calcium signaling ENSG00000156026 PMC5731952__F7 Comprehensive genomic meta-analysis identifies confirmatory role of OBSCN gene in breast tumorigenesis ENSG00000154358 ENSG00000163914 ENSG00000168036 PMC6372765__F1 Signaling pathways involved in sarcopenia , ENSG00000163833 ENSG00000198793 ENSG00000169047 ENSG00000135414 ENSG00000168036 ENSG00000140443 PMC12001728__F3 Intricate regulatory mechanisms of programmed death 1 in tumor cells ENSG00000198793 PMC11076696__F3 GLP-1RAs in reducing macrophage inflammation and foam cell formation ENSG00000278718 ENSG00000162711 ENSG00000172216 ENSG00000198793 ENSG00000086991 ENSG00000132478 PMC11076696__F2 GLP-1RAs in protecting endothelial cell function ENSG00000162692 PMC8294576__F3 Mitochondrial metabolism regulates macrophage biology ENSG00000162711 ENSG00000239732 ENSG00000164430 ENSG00000125538 PMC10887252__F5 Molecular mechanisms for the involvement of the JNK pathway in insulin resistance ENSG00000105550 ENSG00000169047 PMC7352595__F9 Biosynthesis pathway of phenylpropanoid in P ENSG00000126353 ENSG00000084774 PMC6305585__F4 APOBECs-mediated RNA editing in cancer development ENSG00000111701 ENSG00000196712 PMC6305585__F7 APOBEC1-mediated RNA editing in metabolic disorders ENSG00000111701 ENSG00000132478 PMC6305585__F6 ADAR2-mediated RNA editing in metabolic disorders PMC7545690__F1 Flow chart for selecting SNPs in the folic acid metabolic pathway genes ENSG00000086205 ENSG00000178573 PMC9693075__F1 Molecular Mechanism of Natural Products Activating Wnt/Beta-Catenin Signaling Pathway for Improving Hair Loss ENSG00000138798 ENSG00000168036 ENSG00000164690 ENSG00000128602 ENSG00000146648 PMC6449083__F10 ANAC044/ANAC085-mediated pathway involved in stress-induced G2 arrest ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000051180 ENSG00000121211 PMC7456948__F1 MSCs in regulating the IL-10 producing regulatory B cells ENSG00000178860 ENSG00000105246 PMC6305585__F3 ADAR2-mediated RNA editing in cancer development ENSG00000145604 ENSG00000125249 ENSG00000122218 ENSG00000159461 ENSG00000146477 ENSG00000163453 ENSG00000130402 ENSG00000148848 PMC6305585__F2 ADAR1-mediated RNA editing in cancer development ENSG00000228716 ENSG00000011677 ENSG00000173599 ENSG00000106772 ENSG00000166619 ENSG00000118816 ENSG00000198125 ENSG00000168610 PMC7429633__F2 Pathway to protein phosphorylation and cysteine modification of sarcoplasmic reticulum Ca2+ handling proteins ENSG00000198626 PMC8068766__F4 Transcriptome profiles associated with selenium-deficiency-dependent oxidative stress identify potential diagnostic and therapeutic targets in liver cancer cells ENSG00000128951 ENSG00000198793 ENSG00000113140 ENSG00000155876 ENSG00000077514 ENSG00000100162 ENSG00000111602 ENSG00000111665 ENSG00000143476 ENSG00000115942 ENSG00000135336 ENSG00000140284 ENSG00000147536 PMC3143653__F6 Ingenuity pathway analysis of PKCAlpha-CT regulated, MEF2-targetted cardiac mRNAs ENSG00000110711 ENSG00000172216 ENSG00000169474 ENSG00000164627 ENSG00000113520 ENSG00000162772 ENSG00000086730 ENSG00000132170 PMC8884377__F1 Endothelial-Mesenchymal Transition or Functional Tissue Regeneration – Two Outcomes of Heart Remodeling ENSG00000110799 ENSG00000130234 ENSG00000170558 ENSG00000168610 PMC5863502__F2 Beneficial effects of immunobiotics on the antiviral innate immune response against rotavirus in bovine intestinal epithelial (BIE) cells ENSG00000088888 ENSG00000105397 ENSG00000164342 ENSG00000060762 PMC5863502__F1 Antiviral Innate immune response against rotavirus in bovine intestinal epithelial (BIE) cells ENSG00000169245 ENSG00000088888 ENSG00000175104 ENSG00000164342 ENSG00000060762 PMC11975626__F2 Interactions between immune cells and cancer‐associated fibroblasts (CAFs) ENSG00000087245 ENSG00000108691 ENSG00000107562 ENSG00000136869 ENSG00000083799 ENSG00000121807 ENSG00000168610 ENSG00000121966 PMC4452922__F7 IFN pathway in response to virus infection at 24 hpi ENSG00000213928 ENSG00000111537 ENSG00000033800 ENSG00000125347 ENSG00000230034 PMC11975626__F4 Exosomes between urinary system tumours and cancer‐associated fibroblasts (CAFs) ENSG00000122566 ENSG00000019991 ENSG00000198793 ENSG00000108375 ENSG00000180875 ENSG00000168610 ENSG00000146648 PMC11975626__F3 Symbiotic relationship between cancer‐associated fibroblasts (CAFs) and prostate cancer (PCa) ENSG00000131473 ENSG00000198793 ENSG00000096717 PMC8275185__F5 Transcriptome Analysis of Chloris virgata, Which Shows the Fastest Germination and Growth in the Major Mongolian Grassland Plant ENSG00000205517 PMC5807036__F2 Tumorigenic proteins significantly upregulated in the IMR-32 cells mapped to the MYCN proto-oncogene, bHLH transcription factor (MYCN) pathway ENSG00000151702 ENSG00000171105 ENSG00000049130 ENSG00000136997 ENSG00000164399 ENSG00000185591 ENSG00000091879 ENSG00000198910 PMC9726313__F8 Network-based pharmacology and molecular docking exploring the “Bupleuri Radix-Scutellariae Radix” mechanism of action in the viral hepatitis B treatment ENSG00000081041 ENSG00000167207 ENSG00000078747 ENSG00000102871 ENSG00000007908 ENSG00000131323 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000026103 PMC3555235__F4 Predicted pathways by the Ingenuity Pathway Analysis software (IPA) according to microarrays results in peripheral blood mononuclear cells (PBMCs) ENSG00000175206 ENSG00000102962 ENSG00000128016 ENSG00000110330 ENSG00000135218 ENSG00000133937 ENSG00000261857 ENSG00000005102 ENSG00000164399 ENSG00000127528 ENSG00000124875 ENSG00000182759 ENSG00000103241 ENSG00000149295 ENSG00000160202 ENSG00000292234 ENSG00000170893 ENSG00000168398 ENSG00000114125 ENSG00000142192 ENSG00000005339 ENSG00000100906 ENSG00000100987 ENSG00000173083 ENSG00000131095 ENSG00000175505 ENSG00000124391 ENSG00000169575 ENSG00000128872 ENSG00000163904 ENSG00000115415 ENSG00000170458 ENSG00000137992 ENSG00000164690 ENSG00000131196 ENSG00000145349 PMC4377021__F5 Pathway for a network related to cell to cell signaling process in the anaplastic thyroid carcinoma ENSG00000109854 ENSG00000170961 ENSG00000004700 ENSG00000198380 ENSG00000011422 ENSG00000118785 ENSG00000165097 ENSG00000169439 ENSG00000011028 ENSG00000090376 PMC4765324__F5 Programming and reprogramming neural cells by (endo-) cannabinoids: from physiological rules to emerging therapies ENSG00000128272 ENSG00000101255 ENSG00000168036 ENSG00000162772 ENSG00000196689 PMC3852811__F1 Metabolic networks of longevity PMC5102790__F2 Merkel Cell Polyomavirus Infection and Merkel Cell Carcinoma ENSG00000171444 ENSG00000138798 ENSG00000203710 ENSG00000168036 PMC3163765__F2 Signal Transducer and Activator of Transcription 5a/b: Biomarker and Therapeutic Target in Prostate and Breast Cancer ENSG00000173757 PMC12086171__F8 Differentially expressed genes in memory CD4+ T cells from donors expressing HLA-DRB1 alleles ENSG00000205810 ENSG00000150045 ENSG00000291603 ENSG00000105329 ENSG00000163519 ENSG00000139187 ENSG00000163599 ENSG00000171791 ENSG00000089692 ENSG00000213658 ENSG00000181847 ENSG00000169429 ENSG00000213809 ENSG00000026103 ENSG00000178096 ENSG00000139193 ENSG00000081041 ENSG00000030419 ENSG00000113088 ENSG00000277943 ENSG00000105374 ENSG00000111537 ENSG00000134545 ENSG00000145649 ENSG00000074966 ENSG00000115009 ENSG00000136689 ENSG00000168685 PMC9271624__F2 Primary Cilia in Pancreatic Beta- and Alpha-Cells: Time to Revisit the Role of Insulin-Degrading Enzyme ENSG00000159224 ENSG00000134982 ENSG00000163914 ENSG00000128602 PMC3044438__F3 Identifying genomic and developmental causes of adverse drug reactions in children ENSG00000228716 ENSG00000065911 ENSG00000136877 ENSG00000137563 ENSG00000132840 ENSG00000118777 ENSG00000164933 ENSG00000120254 ENSG00000116984 ENSG00000284320 ENSG00000086205 ENSG00000100714 ENSG00000124275 PMC6508100__F2 MCD genes and cytoskeletal regulatory pathways ENSG00000166579 ENSG00000066629 ENSG00000163914 ENSG00000077279 ENSG00000173406 ENSG00000109756 PMC4478577__F1 Gut-brain axis for the actions of glucagon-like peptide-1 ENSG00000197635 ENSG00000124733 PMC2546860__F2 Glycerol biosynthesis and other major pathways contributing to cytosolic NAD+/NADH balance in S PMC9396495__F2 Functions and mechanisms of cytosolic phospholipase A2 in central nervous system trauma ENSG00000198670 ENSG00000166278 ENSG00000263238 PMC5216734__F8 Gastrin-induced miR-222 promotes gastric tumor development by suppressing p27kip1 ENSG00000291971 ENSG00000123908 ENSG00000132341 PMC6085545__F8 Primary DAEC expansion and differentiation.(A) Proliferating human DAECs and their fate after induction and feeder removal in vitro ENSG00000070193 ENSG00000161798 ENSG00000138798 ENSG00000140285 PMC8313741__F8 miR-301 regulates the SIRT1/SOX2 pathway via CPEB1 in the breast cancer progression ENSG00000096717 PMC8693501__F8 Extracellular HMGB1 interacts with RAGE and promotes chemoresistance in acute leukemia cells ENSG00000123395 ENSG00000198793 ENSG00000171791 PMC3296207__F1 Intrinsic and exrtinsic pathways of anoikis ENSG00000100290 ENSG00000002330 ENSG00000168040 ENSG00000104081 PMC7695009__F3 Biosynthetic pathways of UDP-GlcA and UDP-GlcNAc ENSG00000109814 ENSG00000100522 ENSG00000013375 PMC84262__F1 IL-1 signaling pathway ENSG00000134070 ENSG00000172936 ENSG00000175104 PMC7695009__F5 Overall view of HA roles in the cancer metabolic pathway ENSG00000147162 ENSG00000198408 ENSG00000026508 PMC7139586__F5 The proposed role of nAChR signaling pathways in ISC function ENSG00000170365 ENSG00000126016 ENSG00000109321 ENSG00000134982 ENSG00000081051 PMC9117997__F1 Metabolism and subcellular enrichment of phosphoinositides ENSG00000112367 ENSG00000109452 ENSG00000040933 ENSG00000115020 PMC5267336__F1 Clinical applications of mouse models for breast cancer engaging HER2/neu ENSG00000138798 ENSG00000198793 ENSG00000136997 PMC2679302__F2 Network contains downregulated genes and identified around NFKB gene ENSG00000288411 ENSG00000103490 ENSG00000110514 PMC5059871__F2 Osteosarcoma cell proliferation is regulated by lncRNAs, including H19, MALAT1, ANCR, and PACER ENSG00000135446 ENSG00000132646 ENSG00000123374 PMC6693703__F1 Mutation‐driven (ligand‐independent) activated Hh pathway in BCC development and invasion ENSG00000106571 ENSG00000128602 PMC4930918__F1 p53 integrates metabolic stress signals to direct cell metabolism ENSG00000026103 PMC4930918__F3 p53 directs lipid and amino acid metabolism during stress ENSG00000131473 ENSG00000240303 ENSG00000144895 ENSG00000026103 PMC4930918__F2 p53 regulates carbohydrate metabolism during glucose starvation ENSG00000180210 ENSG00000065833 ENSG00000135423 ENSG00000005882 ENSG00000078237 ENSG00000284194 ENSG00000082212 PMC5818965__F1 Metabolic changes triggered by ischemic insult and possible evolutions of the injury with the crosstalk between chemokines ENSG00000108702 ENSG00000143185 ENSG00000108691 ENSG00000081041 ENSG00000163734 PMC3061571__F2 Two different ubiquitin ligases control the stability of the Aurora-A and Polo-like kinases ENSG00000134982 ENSG00000176386 ENSG00000166851 ENSG00000117399 ENSG00000072609 PMC7683515__F2 Signaling pathways up and downstream of mTOR complexes ENSG00000173757 PMC11552340__F3 Compounds that target components of WNT pathway ENSG00000134982 ENSG00000168036 ENSG00000173273 PMC11552340__F1 WNT signaling pathways affected by WNT6 in cancer ENSG00000169071 ENSG00000134982 ENSG00000177606 ENSG00000112655 ENSG00000168036 ENSG00000168610 PMC8298276__F1 Drugging multiple same-allele driver mutations in cancer ENSG00000065361 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC3149979__F1 A representative immune response pathway that leads to the disruption of viral release from the plasma membrane ENSG00000276561 PMC11505556__F11 Therapeutic effect of baicalein against insulin resistance (IR) ENSG00000171105 ENSG00000169047 ENSG00000198793 PMC6344597__F6 The amino acid catabolism pathway differs in breast-fed (BF) and formula-fed (FF) infants ENSG00000166278 PMC6273039__F4 The molecular metchanisms of natural polyphenols effects on metastasis ENSG00000170558 ENSG00000198793 ENSG00000154016 PMC3851989__F4 Identification of mutated core cancer modules by integrating somatic mutation, copy number variation, and gene expression data ENSG00000136997 PMC2905316__F2 Involvement of the Notch signaling pathway during endocrine cell differentiation ENSG00000108960 ENSG00000114315 PMC3851989__F3 The fourth module identified by iMCMC in the GBM data and locations of the detected genes in known pathways ENSG00000146648 ENSG00000196712 ENSG00000187714 PMC11085419__F5 Gallic Acid Can Promote Low-Density Lipoprotein Uptake in HepG2 Cells via Increasing Low-Density Lipoprotein Receptor Accumulation ENSG00000130164 ENSG00000135100 ENSG00000015285 ENSG00000146648 ENSG00000169174 PMC12133496__F2 Simple signaling pathway map of SLC7 transporter protein changes affecting Beta-Cell Function and corresponding islet reactions ENSG00000169047 PMC9577001__F2 Cancer-associated mesothelial cells in the progression and therapy of ovarian cancer ENSG00000108691 ENSG00000272398 ENSG00000026508 ENSG00000168610 PMC9577001__F1 Cancer-associated mesothelial cells in the progression and therapy of ovarian cancer ENSG00000019991 ENSG00000137077 ENSG00000179914 ENSG00000026508 ENSG00000198670 ENSG00000108813 ENSG00000160293 PMC5711377__F3 Pathview () plot of the KEGG () pathway showing the Cell mitotic cycle ('HSA 04110') superimposed with RNA-seq expression data corresponding to the log2 -transformed fold change in expression of cell cycle transcripts from HIOs microinjected with E ENSG00000149311 ENSG00000132646 ENSG00000205250 ENSG00000145386 ENSG00000134480 ENSG00000253729 ENSG00000093009 PMC6095977__F1 IRF9 signaling via the JAK–STAT pathway and antagonism by viral proteins ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC3170851__F2 The Multifaceted Roles of Autophagy In Tumors--Implications For Breast Cancer ENSG00000188554 ENSG00000121058 ENSG00000079999 PMC4840027__F2 Quantitative regulation by the TCF/Beta-catenin asymmetry pathway ENSG00000204070 ENSG00000127948 PMC12131380__F7 Working model of this study ENSG00000113494 PMC7440025__F2 Major antiviral functions of TRIM proteins ENSG00000106785 ENSG00000146063 ENSG00000113595 ENSG00000109654 ENSG00000121236 ENSG00000121060 ENSG00000130726 PMC6099292__F5 Ubiquitylated sites in proteins revealed by diGly proteomics in PC9/GR cells ENSG00000261832 ENSG00000110107 ENSG00000119401 ENSG00000072274 ENSG00000103222 ENSG00000232326 ENSG00000074319 ENSG00000150093 ENSG00000087460 ENSG00000292366 ENSG00000185236 ENSG00000130724 ENSG00000053501 ENSG00000107331 ENSG00000178750 ENSG00000155975 ENSG00000166501 ENSG00000122705 ENSG00000004897 ENSG00000146648 ENSG00000140464 ENSG00000023839 ENSG00000141367 PMC4711826__F7 Molecular explanation ENSG00000118785 PMC6198212__F1 Interactions and functions of NRPs ENSG00000019991 ENSG00000291971 PMC9238352__F3 CASP-Model Sepsis Triggers Systemic Innate Immune Responses Revealed by the Systems-Level Signaling Pathways ENSG00000239732 ENSG00000170458 ENSG00000183979 ENSG00000136997 ENSG00000172936 ENSG00000162924 ENSG00000168040 ENSG00000150455 ENSG00000164342 ENSG00000143387 PMC2585593__F1 Diagrammatic representation of pathways associated with aroma production and links to associated metabolic activities ENSG00000196839 ENSG00000123268 ENSG00000102977 PMC3991635__F6 Microarray Analysis of Cell Cycle Gene Expression in Adult Human Corneal Endothelial Cells ENSG00000112576 ENSG00000105329 ENSG00000134982 ENSG00000184182 ENSG00000197629 ENSG00000250254 ENSG00000135476 ENSG00000118971 ENSG00000166851 ENSG00000134480 ENSG00000175054 ENSG00000129757 ENSG00000081377 ENSG00000204634 ENSG00000253729 ENSG00000170027 ENSG00000101224 ENSG00000149311 ENSG00000145604 ENSG00000002822 ENSG00000198176 ENSG00000156970 ENSG00000132646 ENSG00000147082 ENSG00000080839 PMC9238352__F5 CASP-Model Sepsis Triggers Systemic Innate Immune Responses Revealed by the Systems-Level Signaling Pathways ENSG00000084093 ENSG00000133116 ENSG00000121067 ENSG00000136630 PMC5528795__F6 Working model of pyrithione zinc in oral cancer ENSG00000002330 ENSG00000198793 ENSG00000164327 PMC9238352__F4 CASP-Model Sepsis Triggers Systemic Innate Immune Responses Revealed by the Systems-Level Signaling Pathways ENSG00000149311 ENSG00000226275 ENSG00000213658 ENSG00000135960 ENSG00000102871 ENSG00000186716 ENSG00000083799 ENSG00000127948 ENSG00000062485 PMC5513919__F7 Colorectal cancer metastasis signaling pathway ENSG00000175054 ENSG00000002330 PMC9238352__F7 CASP-Model Sepsis Triggers Systemic Innate Immune Responses Revealed by the Systems-Level Signaling Pathways ENSG00000291603 ENSG00000111537 ENSG00000213658 ENSG00000156127 ENSG00000177606 ENSG00000150455 ENSG00000175104 ENSG00000146648 PMC9238352__F6 CASP-Model Sepsis Triggers Systemic Innate Immune Responses Revealed by the Systems-Level Signaling Pathways ENSG00000002330 PMC3991635__F4 Microarray Analysis of Cell Cycle Gene Expression in Adult Human Corneal Endothelial Cells ENSG00000112576 ENSG00000105329 ENSG00000134982 ENSG00000184182 ENSG00000197629 ENSG00000250254 ENSG00000135476 ENSG00000145386 ENSG00000118971 ENSG00000166851 ENSG00000134480 ENSG00000183765 ENSG00000175054 ENSG00000129757 ENSG00000116670 ENSG00000081377 ENSG00000204634 ENSG00000123374 ENSG00000105810 ENSG00000139687 ENSG00000253729 ENSG00000170027 ENSG00000164109 ENSG00000116717 ENSG00000101224 ENSG00000117399 ENSG00000149311 ENSG00000145604 ENSG00000094804 ENSG00000002822 ENSG00000134057 ENSG00000198176 ENSG00000156970 ENSG00000135446 ENSG00000132646 ENSG00000115266 ENSG00000149554 ENSG00000147082 ENSG00000080839 ENSG00000175305 PMC3567494__F1 Two phosphoinositide cycles regulate aspects of lysosome function ENSG00000112367 ENSG00000124102 ENSG00000115008 ENSG00000173599 ENSG00000115020 ENSG00000171759 ENSG00000163820 PMC8745298__F2 Roles and Mechanisms of the Protein Quality Control System in Alzheimer’s Disease ENSG00000128272 ENSG00000144895 ENSG00000185591 ENSG00000100219 ENSG00000167182 ENSG00000127191 ENSG00000115419 PMC6453877__F3 HIF-mediated suppression of ROS ENSG00000185633 ENSG00000151012 ENSG00000092621 ENSG00000023909 PMC6453877__F4 HIF-mediated regulation of mitochondrial mass PMC8656474__F2 Molecular Mechanisms of Resistance to Immunotherapy and Antiangiogenic Treatments in Clear Cell Renal Cell Carcinoma ENSG00000089692 ENSG00000111537 ENSG00000134982 ENSG00000163599 ENSG00000168036 ENSG00000125347 PMC6515249__F3 Natural-product-mediated multi-step regulation of the TRAIL-driven pathway ENSG00000138134 ENSG00000168040 PMC3207473__F7 Model: TTP transition from “hypo- to hypermodified” determines its functional switch ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC6515249__F2 Negative regulation of the TRAIL-driven pathway ENSG00000078747 ENSG00000175104 PMC8791723__F1 Kynurenine Pathway Metabolites as Biomarkers in Alzheimer's Disease ENSG00000188676 PMC6515249__F1 TRAIL (TNF-related apoptosis-inducing ligand)-mediated signaling ENSG00000171791 PMC6631793__F1 Iatrogenic interference with the initiation of antifungal immunity ENSG00000163464 ENSG00000111537 ENSG00000187796 ENSG00000178573 ENSG00000010671 ENSG00000062485 PMC9405736__F1 Lipid Metabolism in Glioblastoma: From De Novo Synthesis to Storage ENSG00000057252 ENSG00000131473 ENSG00000160752 ENSG00000130164 ENSG00000111837 ENSG00000113161 ENSG00000104549 ENSG00000169710 ENSG00000285482 ENSG00000099194 ENSG00000115419 PMC5748986__F2 Protein sequestration at the nuclear periphery ENSG00000143799 ENSG00000100811 ENSG00000101751 ENSG00000171720 ENSG00000132646 ENSG00000165392 ENSG00000162521 ENSG00000166971 ENSG00000077463 PMC5487527__F3 m6A is involved in viral replicationSchematic representation of the intersection between m6A pathway and viral replication ENSG00000145388 ENSG00000149658 ENSG00000198492 ENSG00000091542 ENSG00000165819 PMC5487527__F2 Links between m6A regulation and cancerSchematic representation of m6A pathway components and targets involved in cancer progression ENSG00000145388 ENSG00000163435 ENSG00000133937 ENSG00000091542 ENSG00000146648 ENSG00000165819 ENSG00000278693 PMC7649569__F3 Major milestones in the development of the Hippo signaling pathway ENSG00000186575 ENSG00000168036 PMC9265087__F3 It Takes Two to Tango: A Review of Oncogenic Virus and Host Microbiome Associated Inflammation in Head and Neck Cancer ENSG00000111537 ENSG00000136997 ENSG00000164362 ENSG00000137699 ENSG00000231179 PMC12083488__F1 Tryptophan metabolic pathway ENSG00000106546 PMC6138823__F3 Hepatitis C virus-apolipoprotein interactions: molecular mechanisms and clinical impact ENSG00000130164 ENSG00000100979 ENSG00000160179 PMC6470603__F8 Compound 3f exerted anti-pulmonary fibrosis activity via repression of the TGFB/Smad signaling pathway ENSG00000291748 PMC8699381__F3 Endocannabinoid System and Tumour Microenvironment: New Intertwined Connections for Anticancer Approaches ENSG00000149311 ENSG00000100219 ENSG00000146648 ENSG00000196689 PMC8322984__F9 Targeting Tristetraprolin Expression or Functional Activity Regulates Inflammatory Response Induced by MSU Crystals ENSG00000162711 ENSG00000125538 PMC5340232__F7 Reduced expression of FILIP1L, a novel WNT pathway inhibitor, is associated with poor survival, progression and chemoresistance in ovarian cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168386 ENSG00000168036 PMC8117616__F7 Integrative genomics of the mammalian alveolar macrophage response to intracellular mycobacteria ENSG00000259207 ENSG00000143878 ENSG00000110799 ENSG00000168036 PMC11767231__F4 Inborn Errors of Immunity Presenting with Early-Onset Severe Atopy ENSG00000159753 ENSG00000015285 PMC11767231__F1 CBM complex controls T cell signaling by the mammalian target of rapamycin (mTOR), nuclear factor kappa B (NFKB), and c-Jun N-terminal kinase activation (JNK) ENSG00000141527 ENSG00000198793 ENSG00000159753 ENSG00000198286 PMC11767231__F2 The JAK/STAT pathways contain various factors, including STAT5, which leads to myeloid activation, or STAT3, which upregulates transcription of the gene ZNF341 ENSG00000115415 ENSG00000173757 ENSG00000168610 PMC9687819__F3 Alteration of the IFN-Pathway by Human Papillomavirus Proteins: Antiviral Immune Response Evasion Mechanism ENSG00000164430 ENSG00000125347 PMC7983022__F1 Hepcidin and iron homeostasis ENSG00000140564 ENSG00000178752 ENSG00000198793 ENSG00000105697 PMC9687819__F2 Alteration of the IFN-Pathway by Human Papillomavirus Proteins: Antiviral Immune Response Evasion Mechanism ENSG00000213928 ENSG00000164430 ENSG00000134321 ENSG00000105397 ENSG00000089127 ENSG00000115415 ENSG00000147896 PMC9233125__F3 Link between inflammatory mediators, autophagy, and metabolic reprogramming ENSG00000125166 ENSG00000081041 ENSG00000162892 PMC5053521__F6 Sphingosine 1-Phosphate Activation of EGFR As a Novel Target for Meningitic Escherichia coli Penetration of the Blood-Brain Barrier ENSG00000063176 ENSG00000113070 ENSG00000146648 PMC9233125__F2 Genetic alterations induce metabolic reprogramming in PDAC ENSG00000136997 ENSG00000153574 PMC9233125__F1 Box 1. Molecular subtypes and metabolic reprogramming in PDAC ENSG00000126778 ENSG00000100625 ENSG00000159399 PMC3734370__F1 Regulated secretory pathway of a model neuroendocrine cell ENSG00000171105 ENSG00000104112 ENSG00000115138 ENSG00000166603 ENSG00000134243 ENSG00000171951 ENSG00000089199 PMC6499807__F9 Mechanistic scheme of lncRNA lnc-TALC in GBM ENSG00000170430 ENSG00000168610 PMC6694743__F6 Physiopathology of JCPyV in the brain ENSG00000169047 ENSG00000185591 ENSG00000196712 PMC7913544__F2 Functional roles of E3 ubiquitin ligases (blue) and DUBs (pink) in the ER stress and ERAD signaling pathway ENSG00000165188 ENSG00000163930 ENSG00000180667 ENSG00000128272 ENSG00000144895 ENSG00000172046 ENSG00000178828 ENSG00000102178 ENSG00000113734 ENSG00000101557 PMC9656873__F3 COVID-19 Molecular Pathophysiology: Acetylation of Repurposing Drugs ENSG00000183735 ENSG00000164430 ENSG00000130234 PMC7324671__F7 Proposed working model for IL-21-induced B cell differentiation and IgA-producing plasma cells in porcine Peyer's patches ENSG00000115415 ENSG00000196092 ENSG00000103522 ENSG00000168610 PMC8285903__F8 GAS6-AXL signaling pathway triggers actin remodeling that drives membrane ruffling, macropinocytosis, and cancer-cell invasion ENSG00000167601 PMC10758279__F2 In Vitro and In Vivo Analysis of Neurotrophin-3 Activation of Arf6 and Rac-1 ENSG00000156299 ENSG00000165527 ENSG00000161835 PMC4900611__F7 HCV-Mediated Apoptosis of Hepatocytes in Culture and Viral Pathogenesis ENSG00000143799 ENSG00000142192 ENSG00000002330 ENSG00000102871 ENSG00000196954 ENSG00000171791 ENSG00000168040 ENSG00000127191 ENSG00000197694 ENSG00000086758 ENSG00000148935 ENSG00000115317 ENSG00000160049 ENSG00000100290 PMC6971376__F4 Pleiotropic role of miR-486-5p in manipulating several target genes in different cellular contexts.miR-486-5p has several targets in different malignant and non-malignant conditions ENSG00000033327 ENSG00000102837 ENSG00000151239 ENSG00000126003 ENSG00000166147 PMC9656873__F1 COVID-19 Molecular Pathophysiology: Acetylation of Repurposing Drugs ENSG00000162711 ENSG00000130234 ENSG00000123374 PMC7574589__F1 Scheme of mannose metabolism in MPI deficient cell ENSG00000142192 PMC2956378__F7 Thrombin-induced ET-1 secretion in RPE is rho/ROCK1/2 dependent ENSG00000285109 ENSG00000067900 ENSG00000179348 PMC8919593__F8 Extracellular signal-regulated kinase regulates microglial immune responses in Alzheimer’s disease ENSG00000141086 ENSG00000177606 ENSG00000026103 PMC11521927__F3 Various signaling pathways activated by TGFB1 stimulation and their partial cross-talk are outlined ENSG00000137834 ENSG00000198742 ENSG00000175104 ENSG00000171621 ENSG00000076604 PMC7820616__F7 Survival of salivary gland cancer stem cells requires mTOR signaling ENSG00000168283 ENSG00000198793 ENSG00000164327 PMC11941073__F1 GOLPH3 regulates the spatial distribution of glycosyltransferases within the Golgi cisternae ENSG00000113384 ENSG00000198793 ENSG00000073849 PMC4276909__F1 miRs regulate vascular medial calcification PMC6433576__F1 Regulation Mechanism of Long Noncoding RNAs in Colon Cancer Development and Progression ENSG00000165119 ENSG00000134982 PMC2810550__F2 Wnt signaling pathway involvement in cancer and neurodegeneration ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC12065877__F1 Differentially expressed transcripts mapping to the canonical HIF-1A signaling pathway in shunt PAECs, as mapped by Ingenuity Pathway Analysis Canonical pathway analysis, p-value of ENSG00000134086 ENSG00000084676 ENSG00000100387 ENSG00000163235 ENSG00000148926 ENSG00000177606 ENSG00000154582 ENSG00000049768 ENSG00000124762 ENSG00000007171 ENSG00000132341 PMC8531525__F1 Targeting Microglial Alpha-Synuclein/TLRs/NF-kappaB/NLRP3 Inflammasome Axis in Parkinson’s Disease ENSG00000162711 ENSG00000136869 ENSG00000142082 PMC4259953__F3 Possible mechanisms of expression and functional regulation of tissue factor and coagulation factor VII in breast cancer cells ENSG00000117525 ENSG00000198793 ENSG00000146648 PMC4792035__F1 Emerging functions of amphiregulin in orchestrating immunity, inflammation and tissue repair ENSG00000109321 ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000146648 PMC4867399__F2 Illustrated summary of Hedgehog pathway and its effetcs at different stages in the formation and progression of ductal pancreatic carcinoma ENSG00000107562 ENSG00000164690 ENSG00000128602 ENSG00000121966 PMC4270428__F1 Multitask Learning of Signaling and Regulatory Networks with Application to Studying Human Response to Flu ENSG00000173163 ENSG00000103266 ENSG00000284832 ENSG00000005339 ENSG00000181163 ENSG00000173039 ENSG00000109654 ENSG00000196470 ENSG00000099942 ENSG00000121774 ENSG00000149311 ENSG00000245848 ENSG00000125398 ENSG00000132646 ENSG00000136997 ENSG00000167986 ENSG00000185591 ENSG00000121060 ENSG00000130726 PMC6393348__F2 Activated STAT3/5 signaling pathway by IL-6 receptor, Prolactin (PRL) receptor, VEGF Receptor, EGF Receptor, and IL-10 receptor ENSG00000138798 ENSG00000168610 ENSG00000146648 ENSG00000113494 PMC3412972__F2 Proteins and protein isoforms in glycolysis/gluconeogenesis, TCA cycle, pentose phosphate pathway, galactose metabolism, and glutamine metabolism pathways ENSG00000130957 ENSG00000197713 ENSG00000160883 ENSG00000067057 ENSG00000278373 ENSG00000153574 ENSG00000172340 ENSG00000074800 ENSG00000156958 ENSG00000100412 ENSG00000116649 ENSG00000136872 ENSG00000091140 ENSG00000115419 ENSG00000169299 ENSG00000152556 ENSG00000062485 PMC7894404__F1 Model‐Informed Pediatric Dose Selection for Dapagliflozin by Incorporating Developmental Changes ENSG00000171234 PMC12059460__F6 HPE inhibits allergic rhinitis by modulating the AMPK/SHP1/SHP2/STING signaling pathway ENSG00000183735 ENSG00000146648 PMC7672255__F2 CYP1B1 as a therapeutic target in cardio-oncology ENSG00000106546 PMC12163474__F14 Efficacy and Safety of Natural Apigenin Treatment for Alzheimer's Disease: Focus on In vivo Research Advancements ENSG00000142192 ENSG00000115415 ENSG00000125538 ENSG00000087085 ENSG00000131095 ENSG00000171791 ENSG00000142082 PMC6066739__F1 ERA subcellular localization allows the activation of both nuclear and membrane-initiated signaling pathways ENSG00000291971 ENSG00000185591 PMC6672276__F11 Regulation of vasopressin gene expression in the SCN ENSG00000146469 PMC9570066__F7 Dietary Koumine on Growth Performance, Intestinal Morphology, Microbiota, and Intestinal Transcriptional Responses of Cyprinus carpio PMC11543427__F3 The formation of VSMC-derived foam cells induced by ox-LDL ENSG00000135218 ENSG00000112561 ENSG00000077463 PMC8198168__F2 Epigenomic and Metabolomic Integration Reveals Dynamic Metabolic Regulation in Bladder Cancer ENSG00000115548 ENSG00000198793 ENSG00000136997 ENSG00000115419 ENSG00000107077 PMC8198168__F1 Epigenomic and Metabolomic Integration Reveals Dynamic Metabolic Regulation in Bladder Cancer ENSG00000004487 ENSG00000115419 ENSG00000026103 PMC5656721__F3 Interplay in the synthesis and actions of the 2-acylglycerols and ethanolamides derived from ARA, DHA and EPA ENSG00000100439 ENSG00000196689 PMC8642436__F6 A potent FKBP38 agonist that ameliorates HFD-induced hyperlipidemia via mTOR/P70S6K/SREBPs pathway ENSG00000198793 ENSG00000113161 ENSG00000169710 PMC4581242__F1 UPRmt models in mammalians ENSG00000144895 ENSG00000136758 ENSG00000125656 ENSG00000106459 ENSG00000115317 PMC2527273__F2 The signaling pathway of Type II, FasL signaling-induced apoptosis, adapted from Bagci et al ENSG00000132906 ENSG00000064012 ENSG00000164305 PMC10152985__F15 Protein posttranslational modifications in health and diseases: Functions, regulatory mechanisms, and therapeutic implications ENSG00000145604 ENSG00000033178 ENSG00000163930 ENSG00000069869 ENSG00000150991 ENSG00000100387 ENSG00000081307 ENSG00000086758 ENSG00000121060 ENSG00000123124 ENSG00000109670 ENSG00000182179 PMC4365348__F5 Shared pathway/ GO categories for DEGs from liver and skeletal muscle tissues ENSG00000134086 ENSG00000213741 ENSG00000197728 ENSG00000173039 ENSG00000149806 ENSG00000112306 ENSG00000161960 PMC7873896__F4 Therapeutic molecules that target Wnt signaling pathway at the level of the plasma membrane ENSG00000281324 ENSG00000162337 ENSG00000125084 PMC9421153__F5 Targeting TRAF3IP2 inhibits angiogenesis in glioblastoma ENSG00000138798 ENSG00000125538 ENSG00000198793 ENSG00000112715 ENSG00000146648 PMC7873896__F2 Wnt signaling pathways at the plasma membrane ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000058091 ENSG00000168036 ENSG00000108375 PMC11983633__F6 Ribosomal protein L9 is a potential therapeutic target for B-ALL through the activation of the p53 signaling pathway ENSG00000231179 ENSG00000204520 PMC2605957__F7 Unsaturated fatty acid regulation of cytochrome P450 expression via a CAR-dependent pathway ENSG00000019991 ENSG00000135218 ENSG00000127948 PMC3621649__F1 Targeted therapy pathways.Notes: Protein kinase B (AKT) is a serine/threonine-specific protein kinase that affects glucose metabolism, apoptosis, cell proliferation, transcription and cell migration ENSG00000115415 ENSG00000198793 ENSG00000168610 PMC7958478__F2 Pathways linking coronavirus disease 2019 to heart/brain injury ENSG00000169245 ENSG00000164136 PMC2886346__F10 The pathway signaling to ERESs ENSG00000138798 ENSG00000095015 ENSG00000146648 ENSG00000196712 PMC4957615__F1 Actin and myosins in mammalian autophagy ENSG00000156232 ENSG00000123240 ENSG00000197879 ENSG00000196586 PMC7218174__F3 Autophagic compensation in resistance to MET-targeted therapy ENSG00000177169 ENSG00000019991 ENSG00000198793 ENSG00000115419 PMC4951264__F8 Rac1b enhances cell survival through activation of the JNK2/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways PMC6999540__F1 An overview of metabolic engineering of Y ENSG00000065833 ENSG00000197429 ENSG00000198670 ENSG00000034693 ENSG00000047597 ENSG00000026103 ENSG00000158125 PMC2784662__F1 mTOR Signaling Cascade ENSG00000163435 ENSG00000198793 ENSG00000164327 PMC8628461__F5 Comprehensive analysis of miRNA–mRNA regulatory network and potential drugs in chronic chagasic cardiomyopathy across human and mouse ENSG00000101146 ENSG00000213658 ENSG00000117091 ENSG00000172005 ENSG00000231179 ENSG00000204520 ENSG00000164305 ENSG00000026103 PMC5814270__F5 Network analysis of microRNAs, genes and their regulation in diffuse and follicular B-cell lymphomas ENSG00000150281 ENSG00000102760 ENSG00000128342 ENSG00000146648 PMC3158334__F1 Possible mechanisms of opioid receptor mediated influence of morphine on tumor growth ENSG00000172680 ENSG00000002330 ENSG00000291971 ENSG00000138798 PMC11177111__F0 miR-1202 regulates BPH-1 cell proliferation, apoptosis, and epithelial-to-mesenchymal transition through targeting HMGCL ENSG00000168036 ENSG00000117305 PMC9604112__F1 Etiology of IBD—Is It Still a Mystery? ENSG00000134982 ENSG00000115009 PMC7439917__F1 ACE2 downregulation by SARS-CoV-2 induces pericyte damage and microvascular dysfunction ENSG00000130234 ENSG00000184012 PMC2633485__F8 Proposed mechanism of PDGF signaling in the lens epithelial cells ENSG00000291971 ENSG00000146648 PMC4394028__F1 TLR/IL-1R, RLR, cGAS, and inflammasome signaling pathways ENSG00000162711 ENSG00000163568 ENSG00000091106 ENSG00000276068 ENSG00000164430 ENSG00000088888 ENSG00000187554 ENSG00000172005 ENSG00000125538 ENSG00000134070 ENSG00000136869 ENSG00000172936 ENSG00000184216 ENSG00000164342 PMC7678304__F3 Literature-based illustration of TNFA signaling pathway in the presence and absence of macrophages ENSG00000132906 ENSG00000168610 ENSG00000064012 PMC8234951__F3 Chemopreventive and Therapeutic Proprieties of Ginger Extracts in Cancer ENSG00000198793 ENSG00000168036 ENSG00000168610 PMC6660575__F1 Posited mechanistic frameworks implicating dietary carbohydrates and cancer risk ENSG00000129214 PMC8239365__F5 IGFBP2 Is a Potential Master Regulator Driving the Dysregulated Gene Network Responsible for Short Survival in Glioblastoma Multiforme ENSG00000087245 ENSG00000198793 ENSG00000112715 ENSG00000168610 ENSG00000197461 ENSG00000145623 ENSG00000115415 ENSG00000115457 ENSG00000177606 ENSG00000106624 ENSG00000100985 ENSG00000146648 ENSG00000140443 PMC8070923__F2 Main mechanisms by which active skeletal muscle can impact the brain ENSG00000160097 ENSG00000096717 PMC6212468__F2 Integrin linked kinase (ILK) signaling ENSG00000163914 PMC12067395__F2 Interactions between tumors and copper ENSG00000123191 ENSG00000136997 ENSG00000177556 ENSG00000168036 ENSG00000146648 PMC2873428__F8 Sequencing, Analysis, and Annotation of Expressed Sequence Tags for Camelus dromedarius ENSG00000079999 PMC9659858__F1 Clinical implication of genetic composition and molecular mechanism on treatment strategies of HER2-positive breast cancers ENSG00000108691 ENSG00000149269 ENSG00000135446 ENSG00000105810 ENSG00000171791 PMC7459525__F6 The possible FDNCR1-miR-204-TGFBR1 pathway in porcine preadipocyte differentiation PMC11743317__F6 Signaling pathways of duck RIG-I in gene-edited DF1 chicken cells ENSG00000088888 ENSG00000157601 ENSG00000125347 ENSG00000121060 ENSG00000276561 ENSG00000164342 PMC6212468__F3 Rho GTPase family signaling ENSG00000163914 ENSG00000015285 ENSG00000080823 ENSG00000132478 PMC8431732__F2 Nrf2/ARE Pathway and Its Role in Neurodegenerative Diseases ENSG00000012048 ENSG00000083093 ENSG00000254986 ENSG00000010810 ENSG00000177606 ENSG00000136997 ENSG00000284099 ENSG00000185591 ENSG00000247077 ENSG00000106546 ENSG00000079999 PMC3303610__F3 Ang-(1-7) signaling in cardiomyocytes PMC2886330__F1 Simplified diagram of the two major pathways affected by EGFR-mediated signaling in malignant glioma cells ENSG00000198793 ENSG00000146648 PMC6212468__F8 Main effects on pathways in the metabolic syndrome hearts (DKO) versus WT hearts and for both mouse models the effect of ACE-I ENSG00000245848 ENSG00000005339 ENSG00000102908 ENSG00000173039 PMC3883963__F3 HMGB1-TLR4 signaling mediates liver I/R injury ENSG00000170458 ENSG00000189403 ENSG00000136869 PMC8849213__F2 Protein C Pathway in Paediatric and Neonatal Sepsis ENSG00000170458 ENSG00000125538 ENSG00000173599 ENSG00000136869 PMC6521864__F3 Synthesis pathway of cardiolipin from lysophosphatidic acid and lysophosphatidylcholine ENSG00000184207 ENSG00000110536 PMC6733035__F1 Lineage of Cytotoxic Innate Lymphocyte Differentiation ENSG00000138615 PMC5806469__F5 Extended compartmentalized lignin pathway model in B ENSG00000084774 PMC7060546__F3 Roles of (P) RR in pathways that contribute to oncogenesis, as well as cancer progression and metastasis ENSG00000281324 ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC5806469__F1 Putative lignin biosynthesis pathway with identification of species-specific reactions ENSG00000090402 ENSG00000084774 PMC11351712__F7 Graphical abstract ENSG00000188486 ENSG00000164690 ENSG00000128602 PMC6150077__F1 Diagram of gemcitabine metabolism and proposed mechanisms of gemcitabine resistance ENSG00000167325 ENSG00000171848 PMC5859839__F7 Pathway o of DXP-ER-positive breast cancer network (blue circle stands for compound target; red diamond stands for pathway; green hexagon stands for herb) ENSG00000157404 ENSG00000291603 ENSG00000070831 ENSG00000291971 ENSG00000198793 ENSG00000147231 ENSG00000113161 ENSG00000169032 ENSG00000010671 ENSG00000179295 ENSG00000004455 ENSG00000276870 ENSG00000128052 ENSG00000140443 ENSG00000162889 ENSG00000087245 ENSG00000171105 ENSG00000157764 ENSG00000007908 ENSG00000143933 ENSG00000105639 ENSG00000007171 ENSG00000132170 ENSG00000066468 ENSG00000188130 ENSG00000100985 PMC4519954__F13 Endocytosis signaling pathway ENSG00000131475 ENSG00000124102 ENSG00000013016 ENSG00000130164 ENSG00000110395 ENSG00000136100 ENSG00000138798 ENSG00000074319 ENSG00000165527 PMC4519954__F12 Lysosome signaling pathway ENSG00000107331 ENSG00000291507 ENSG00000127415 ENSG00000198951 ENSG00000103174 ENSG00000038002 ENSG00000169919 PMC4519954__F11 ERBB signaling pathway ENSG00000169291 ENSG00000002330 ENSG00000110395 ENSG00000113070 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000136997 ENSG00000158458 ENSG00000169752 PMC4519954__F10 MAPK signaling pathway ENSG00000172680 ENSG00000170458 ENSG00000177606 ENSG00000130159 ENSG00000175104 ENSG00000026103 PMC5734789__F8 Histamine Receptor 3 negatively regulates oligodendrocyte differentiation and remyelination ENSG00000197971 ENSG00000273529 PMC7451686__F1 Working model for mTORC1/p70S6K signaling regulation of Beta-TrCP-mediated PD-L1 degradation ENSG00000198793 ENSG00000113558 ENSG00000155792 ENSG00000167965 PMC7762487__F8 PPI network and KEGG pathway analysis for the differentially expressed MAM proteins in PSD and PDZ rats ENSG00000277586 ENSG00000172380 ENSG00000165478 ENSG00000175166 ENSG00000184831 ENSG00000006451 ENSG00000117758 ENSG00000197746 ENSG00000170348 ENSG00000291720 ENSG00000101558 ENSG00000101210 PMC3444437__F9 C-srcregulating primordial follicle activation and growth through PI3K → PKC → MAPK signaling pathway ENSG00000090402 ENSG00000291971 PMC5805631__F5 Personalized proteomics in proliferative vitreoretinopathy implicate hematopoietic cell recruitment and mTOR as a therapeutic target ENSG00000111537 ENSG00000198793 ENSG00000146678 ENSG00000164327 ENSG00000007908 ENSG00000145777 ENSG00000141564 ENSG00000064300 ENSG00000026103 PMC3581417__F1 Synthesis of DNA precursors in the cytosol and mitochondria ENSG00000167900 PMC4973221__F3 Transcriptome landscape of Synechococcus elongatus PCC 7942 for nitrogen starvation responses using RNA-seq ENSG00000073578 ENSG00000173599 ENSG00000153574 ENSG00000127948 ENSG00000169299 PMC9329168__F1 Improving Treatment Options for Primary Hyperoxaluria PMC11756006__F1 Molecular signaling of nucleotide-binding domain, leucine-rich repeat, and pyrin domain-containing protein 3 priming and activation ENSG00000278718 ENSG00000162711 ENSG00000172936 PMC7057842__F2 Post-Translational Regulations of Transcriptional Activity of RUNX2 ENSG00000127445 ENSG00000135446 PMC5664350__F4 Summary of intracellular TLR4 signalling in platelets ENSG00000145321 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC5664350__F3 Summary of intracellular TLR4 signalling pathways in nucleated cells ENSG00000170458 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC153558__F3 Model of the maternal Radar signaling pathway mediating early steps of dorsoventral axis formation ENSG00000170365 PMC3743157__F3 RB1 pathway indicating genes with mutations in this series ENSG00000135446 ENSG00000105810 ENSG00000128602 ENSG00000139687 PMC3112459__F1 TGFB signalling pathway and breast cancer susceptibility ENSG00000049323 ENSG00000170365 ENSG00000137834 ENSG00000105329 ENSG00000119681 PMC11756006__F2 Molecular and cellular signaling pathways of nucleotide-binding domain, leucine-rich repeat, and pyrin domain-containing protein 3 in obesity, diabetes, and other metabolic diseases ENSG00000162711 ENSG00000135218 ENSG00000111537 ENSG00000136869 PMC6314136__F6 Dynamic gene expression profiles of CIK cells involved in the cell cycle and the natural killer cell–mediated cytotoxicity pathway ENSG00000112576 ENSG00000118007 ENSG00000118971 ENSG00000164305 ENSG00000093009 ENSG00000145604 ENSG00000094804 ENSG00000101972 ENSG00000112242 ENSG00000100387 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000026103 PMC8833717__F3 Fluorescence Imaging of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Resistance in Non-Small Cell Lung Cancer ENSG00000002330 ENSG00000026103 PMC4701085__F10 Molecular pathways affected by Gcm ENSG00000089472 ENSG00000133961 ENSG00000128602 PMC4261819__F1 Network of noncoding RNAs negatively regulates NFKB signaling ENSG00000166167 ENSG00000134070 ENSG00000127528 ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000136826 ENSG00000100065 PMC6150077__F2 Diagrams of the Hedgehog, Wnt, Notch pathways and their roles for gemcitabine resistance ENSG00000106571 ENSG00000134982 ENSG00000168036 ENSG00000128602 PMC5859839__F3 Pathway of ER-positive breast cancer target PPI network (blue circle stands for breast cancer gene; red diamond stands for pathway) ENSG00000291971 ENSG00000221914 ENSG00000138798 ENSG00000198793 ENSG00000171791 ENSG00000166851 ENSG00000121879 ENSG00000073756 ENSG00000173757 ENSG00000149269 ENSG00000128052 ENSG00000136997 ENSG00000096717 ENSG00000146648 PMC5037530__F1 The gSkM transcriptome for the comparison of HFD-ED and HFD-corn oil fed mice ENSG00000157184 ENSG00000143252 ENSG00000117054 ENSG00000136521 ENSG00000131174 ENSG00000117118 ENSG00000115361 ENSG00000138777 ENSG00000099795 ENSG00000105953 ENSG00000119013 ENSG00000131828 PMC11005242__F7 GLUT3-mediated cigarette smoke-induced epithelial-mesenchymal transition in chronic obstructive pulmonary disease through the NF-kB/ZEB1 pathway PMC7348946__F3 Simplified overview of the CD28, PD-1, and TCR signaling pathways in T cells ENSG00000089692 ENSG00000073861 PMC11697715__F3 Histone lactylation changes in tumor-associated macrophages ENSG00000118520 ENSG00000175104 PMC7348946__F2 Simplified overview of the TCR and CD28 signaling pathways in T cells PMC7348946__F1 Simplified overview of NK cell activation by the NKG2D pathway ENSG00000131015 ENSG00000131019 ENSG00000111981 ENSG00000231179 ENSG00000204520 ENSG00000141968 PMC10983073__F3 Diagram of the inhibition of TSLP Signaling by HZ-1127 and TEZE ENSG00000145777 ENSG00000168610 PMC9433749__F1 Gearing up for battle: Harnessing adaptive T cell immunity against gram-negative pneumonia ENSG00000109321 ENSG00000134982 ENSG00000163739 PMC4282639__F6 Chronic exposure to TGFB1 regulates myeloid cell inflammatory response in an IRF7-dependent manner ENSG00000081041 ENSG00000105329 ENSG00000163739 ENSG00000276561 PMC4756317__F6 GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway ENSG00000069482 ENSG00000163479 PMC3657472__F1 Genetic predisposition to peripheral nerve neoplasia: Diagnostic criteria and pathogenesis of neurofibromatoses, Carney complex, and related syndromes ENSG00000026508 PMC8408559__F5 Unique somatic variants in DNA from urine exosomes of individuals with bladder cancer ENSG00000157554 ENSG00000104856 ENSG00000102962 ENSG00000181163 ENSG00000007237 ENSG00000265972 ENSG00000120885 ENSG00000171791 ENSG00000122194 ENSG00000008853 ENSG00000125813 ENSG00000012048 ENSG00000151702 ENSG00000157557 ENSG00000134086 ENSG00000159216 ENSG00000130164 ENSG00000126217 ENSG00000178573 ENSG00000110777 ENSG00000090924 ENSG00000179348 ENSG00000133818 ENSG00000182158 ENSG00000285109 ENSG00000135903 ENSG00000137193 ENSG00000158169 ENSG00000150457 ENSG00000131023 ENSG00000168610 ENSG00000277943 ENSG00000115884 ENSG00000108691 ENSG00000110395 ENSG00000186716 ENSG00000134853 ENSG00000291791 ENSG00000075891 ENSG00000196092 ENSG00000205927 ENSG00000198355 PMC5762387__F5 MEF2 signaling and human diseases ENSG00000149782 ENSG00000168036 ENSG00000213999 ENSG00000291761 ENSG00000124181 ENSG00000146648 ENSG00000081189 PMC4402595__F2 Relationship between the genes in each module from the GBM dataset ENSG00000111012 ENSG00000135446 ENSG00000121879 ENSG00000146648 ENSG00000139687 ENSG00000198625 PMC2756045__F2 LKB1-AMPK pathway: metabolism and growth control in tumor suppression ENSG00000169047 ENSG00000141068 ENSG00000160741 ENSG00000163788 ENSG00000108840 PMC9160826__F1 Novel Insights in the Regulatory Mechanisms of Ferroptosis in Hepatocellular Carcinoma ENSG00000167468 ENSG00000111684 ENSG00000187855 PMC2756045__F4 LKB1-AMPK pathway: metabolism and growth control in tumor suppression ENSG00000070831 ENSG00000134982 ENSG00000168036 PMC2756045__F3 LKB1-AMPK pathway: metabolism and growth control in tumor suppression ENSG00000169047 ENSG00000198793 ENSG00000196712 ENSG00000140443 PMC2884012__F1 Tuberous Sclerosis Complex: A Brave New World? PMC11932036__F1 Notch Signaling Pathway Interfering as a Possible Asthma Treatment: A Narrative Review ENSG00000148400 ENSG00000074181 PMC7714932__F4 Vascular diseases: the roles of miR-21/miR-21-3p in ECs and VSMCs ENSG00000143878 ENSG00000185591 ENSG00000274286 ENSG00000140416 PMC3206195__F3 Fear Conditioning, Synaptic Plasticity, and the Amygdala: Implications for Posttraumatic Stress Disorder PMC7714932__F3 Cardiac hypertrophy and HF: the roles of miR-21/miR-21-3p in CMs, CFs, and ECs ENSG00000164056 ENSG00000147099 PMC9423097__F2 Interplay between Helicobacter pylori and the gut microbiota: An emerging driver influencing the immune system homeostasis and gastric carcinogenesis ENSG00000162711 ENSG00000049768 PMC4536758__F1 Idelalisib —targeting PI3KD in patients with B cell malignancies ENSG00000107562 ENSG00000186716 ENSG00000277943 ENSG00000121966 PMC4467301__F1 Epithelial–mesenchymal interactions mediated by Sonic Hedgehog pathway in embryonic lung ENSG00000261371 ENSG00000198053 ENSG00000164283 ENSG00000292234 ENSG00000125538 ENSG00000103241 ENSG00000178719 ENSG00000164690 ENSG00000128602 PMC7465890__F10 Asp metabolism after enteral administration within the small intestine (a) and liver (b) and postulated metabolic pathway of Ala in periportal hepatocytes ENSG00000122966 ENSG00000172005 PMC7714932__F2 Ischemic heart disease: the roles of miR-21 in CMs and CFs.Reported major signals in CMs ENSG00000087245 ENSG00000026103 PMC4087218__F4 Resveratrol on protein phosphorylation in the insulin signaling pathway and the mTOR pathway of obese mice ENSG00000169047 ENSG00000198793 PMC10093079__F7 Baicalein inhibits cancer cell progression by targeting P13K/FOXO pathways ENSG00000198793 PMC4582667__F1 Phosphatidic acid: a new therapeutic lead to suppress hepatic glucose production ENSG00000173599 ENSG00000198670 PMC2777795__F2 Negative-feedback loop linking NAD+/SIRT1 with the Clock network ENSG00000105835 ENSG00000096717 PMC4519954__F14 Chemokine signaling pathway ENSG00000169291 PMC10093079__F5 Baicalein in regulating the cancer signaling pathways ENSG00000105722 ENSG00000198793 PMC9160826__F2 Novel Insights in the Regulatory Mechanisms of Ferroptosis in Hepatocellular Carcinoma ENSG00000128016 ENSG00000125144 ENSG00000181019 ENSG00000167468 ENSG00000167996 ENSG00000122873 ENSG00000126432 ENSG00000136381 ENSG00000079999 ENSG00000104064 PMC8273767__F5 Insights Into Transcriptome Profiles Associated With Wooden Breast Myopathy in Broilers Slaughtered at the Age of 6 or 7 Weeks ENSG00000169291 ENSG00000002330 ENSG00000070831 ENSG00000010810 PMC3430547__F4 TORC1 and nitrogen regulation ENSG00000011143 ENSG00000179632 ENSG00000159899 PMC7432414__F6 Putative signaling pathway involved in HRPC–CAF transition mediated by PDGF-BB increase ENSG00000169248 ENSG00000275385 PMC2172491__F1 The PI3K–Akt–TSC–TOR pathway and feedback regulation of insulin/IGF-I signaling ENSG00000002330 PMC8302486__F3 Interferon B, an enhancer of the innate immune response against SARS-CoV-2 infection ENSG00000213928 ENSG00000105397 ENSG00000135114 ENSG00000142089 ENSG00000135828 ENSG00000172183 PMC8684386__F3 Multifunctional Non-Coding RNAs Mediate Latent Infection and Recurrence of Herpes Simplex Viruses ENSG00000213658 ENSG00000145321 ENSG00000185591 ENSG00000107201 ENSG00000162772 ENSG00000102974 PMC9162456__F3 Natural and engineered metabolic pathways to biofuels ENSG00000148926 ENSG00000197429 ENSG00000078098 ENSG00000106546 ENSG00000291368 PMC4944541__F2 Crosstalk between leukemia cell and BM MSCs ENSG00000178860 ENSG00000108691 ENSG00000173039 ENSG00000162692 PMC6692187__F1 IRE1A structure, activation and potential roles in cancer ENSG00000113140 ENSG00000100219 ENSG00000112715 ENSG00000127191 ENSG00000125968 PMC9502172__F8 HSP27 Attenuates cGAS-Mediated IFNB Signaling through Ubiquitination of cGAS and Promotes PRV Infection ENSG00000183735 ENSG00000164430 PMC8234554__F2 An Updated Understanding of the Role of YAP in Driving Oncogenic Responses ENSG00000087095 ENSG00000130545 ENSG00000166025 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC8808072__F9 Polygenic networks in peripheral leukocytes indicate patterns associated with HIV infection and context-dependent effects of cannabis use ENSG00000140992 ENSG00000019991 ENSG00000107404 ENSG00000002330 ENSG00000157764 ENSG00000291971 ENSG00000050748 ENSG00000138798 ENSG00000168036 ENSG00000171791 ENSG00000169032 ENSG00000112715 ENSG00000121879 ENSG00000157500 ENSG00000117020 ENSG00000177189 ENSG00000118785 ENSG00000177606 ENSG00000166501 ENSG00000072110 ENSG00000171608 ENSG00000140443 PMC2695822__F10 Display of genes with high expression in CT embryos ENSG00000285121 PMC8306625__F4 PRR-Mediated Signaling Pathways in the Regulation of Oxidative Stress and Inflammatory Diseases ENSG00000088888 ENSG00000140279 ENSG00000131323 ENSG00000276561 ENSG00000115419 PMC4001295__F7 Opposing TNFA/IL-1Beta- and BMP-2-activated MAPK signaling pathways converge on Runx2 to regulate BMP-2-induced osteoblastic differentiation ENSG00000170365 ENSG00000125538 PMC3270058__F9 Endothelial adaptive response to moderate hypothermia (25°C/72 h) ENSG00000178035 ENSG00000074800 ENSG00000105835 ENSG00000167325 ENSG00000155660 ENSG00000189403 ENSG00000178928 ENSG00000267680 ENSG00000175334 ENSG00000152795 PMC7643190__F1 Biomarkers, molecular pathways, existing and emerging therapeutic targets in colorectal cancer ENSG00000157764 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC3065454__F8 Advanced Computational Biology Methods Identify Molecular Switches for Malignancy in an EGF Mouse Model of Liver Cancer ENSG00000087095 ENSG00000171105 ENSG00000291971 ENSG00000138798 ENSG00000169047 ENSG00000137845 ENSG00000184481 ENSG00000168610 ENSG00000128272 ENSG00000149269 ENSG00000107485 ENSG00000175104 ENSG00000123268 PMC8421619__F1 Investigation of MDMA Inhibitory Effect on CytochromeP450 3A4 in Isolated Perfused Rat Liver Model Using Tramadol ENSG00000197408 PMC5901475__F2 Therapeutic approaches for Treg enrichment in vivo ENSG00000102962 ENSG00000137033 ENSG00000198793 ENSG00000049768 PMC6514096__F4 Interconnection of the pathways studied, the genes in which we have measured expression and connection to mitochondrial respiration ENSG00000196839 ENSG00000116688 ENSG00000198793 ENSG00000158828 ENSG00000175567 ENSG00000096717 ENSG00000142082 PMC7224208__F8 Influenza infection rewires energy metabolism and induces browning features in adipose cells and tissues ENSG00000111537 ENSG00000128272 ENSG00000115415 ENSG00000136997 ENSG00000276561 ENSG00000198911 PMC11554266__F3 This illustration details the PI3K/AKT/mTORC1/HIF1A pathway, focusing on its regulatory role in glucose uptake through GLUT1 and GLUT4 transporters ENSG00000146648 PMC4066219__F2 IL-15: a central regulator of celiac disease immunopathology ENSG00000049768 ENSG00000105639 PMC7438559__F12 Working model of the experimental validation ENSG00000198793 ENSG00000057663 PMC11827889__F1 TrkA/NGF/NRP1/GIPC1 targeting for pain treatment PMC8144624__F5 Health monitoring in birds using bio-loggers and whole blood transcriptomics ENSG00000169245 ENSG00000164066 ENSG00000198517 ENSG00000160703 ENSG00000213341 ENSG00000083799 ENSG00000145782 ENSG00000057663 PMC2713013__F3 MICROBE SENSING, POSITIVE FEEDBACK LOOPS, AND THE PATHOGENESIS OF INFLAMMATORY DISEASES ENSG00000174125 ENSG00000135218 ENSG00000110057 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000170458 ENSG00000172005 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC4141456__F1 Anti-microbial responses ENSG00000172936 ENSG00000162924 ENSG00000168040 PMC316759__F5 Regulation of reproductive growth and metabolism by the DAF-2 insulin receptor-like signaling pathway ENSG00000124102 ENSG00000005882 PMC2713013__F7 MICROBE SENSING, POSITIVE FEEDBACK LOOPS, AND THE PATHOGENESIS OF INFLAMMATORY DISEASES ENSG00000125538 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC8234554__F3 An Updated Understanding of the Role of YAP in Driving Oncogenic Responses ENSG00000136807 ENSG00000167601 ENSG00000108691 ENSG00000109321 ENSG00000136997 ENSG00000102890 ENSG00000108342 ENSG00000125686 ENSG00000184371 ENSG00000164400 ENSG00000171517 ENSG00000159399 PMC8108028__F1 BRCA mutated pancreatic cancer: A change is coming ENSG00000149311 ENSG00000012048 ENSG00000083093 ENSG00000051180 ENSG00000139618 PMC10451182__F2 Intrinsic and extrinsic apoptotic pathways and confirmed target genes of miR-106a ENSG00000168040 ENSG00000185104 ENSG00000026103 PMC6505570__F1 Myxoid liposarcoma: it's a hippo's world ENSG00000150457 ENSG00000166851 ENSG00000131023 PMC3469622__F1 Quantitative Phosphoproteomics Reveals SLP-76 Dependent Regulation of PAG and Src Family Kinases in T Cells ENSG00000177606 ENSG00000162924 ENSG00000113263 PMC3889810__F6 Whole genome and gene set enrichment analysis of cells expressing mutants of neuroserpin show an upregulation of the cholesterol pathway when polymers are expressed ENSG00000160752 ENSG00000067064 ENSG00000110921 ENSG00000112972 ENSG00000001630 ENSG00000172893 ENSG00000113161 ENSG00000104549 ENSG00000167508 ENSG00000198911 PMC8120202__F5 Molecular mechanisms of radioactive iodine refractoriness in differentiated thyroid cancer: Impaired sodium iodide symporter (NIS) expression owing to altered signaling pathway activity and intracellular localization of NIS ENSG00000196531 ENSG00000141867 ENSG00000137834 ENSG00000281324 ENSG00000162337 ENSG00000086991 ENSG00000164362 ENSG00000165409 ENSG00000168036 ENSG00000189403 ENSG00000152689 ENSG00000049768 PMC8120202__F4 Molecular mechanisms of radioactive iodine refractoriness in differentiated thyroid cancer: Impaired sodium iodide symporter (NIS) expression owing to altered signaling pathway activity and intracellular localization of NIS ENSG00000291971 ENSG00000168374 ENSG00000101464 ENSG00000165280 ENSG00000135404 PMC4399414__F11 Hm-MyD88 and Hm-SARM: Two key regulators of the neuroimmune system and neural repair in the medicinal leech ENSG00000131508 ENSG00000175104 PMC8120202__F3 Molecular mechanisms of radioactive iodine refractoriness in differentiated thyroid cancer: Impaired sodium iodide symporter (NIS) expression owing to altered signaling pathway activity and intracellular localization of NIS ENSG00000189403 PMC8120202__F2 Molecular mechanisms of radioactive iodine refractoriness in differentiated thyroid cancer: Impaired sodium iodide symporter (NIS) expression owing to altered signaling pathway activity and intracellular localization of NIS ENSG00000281324 ENSG00000162337 ENSG00000086991 ENSG00000168036 ENSG00000049768 PMC6070887__F2 Metabolic rewiring following T cell activation ENSG00000111537 ENSG00000198793 ENSG00000049768 ENSG00000026103 PMC5400530__F1 Lipid and Alzheimer’s disease genes associated with healthy aging and longevity in healthy oldest-old ENSG00000130208 ENSG00000010704 ENSG00000142192 ENSG00000105329 ENSG00000138823 ENSG00000134982 ENSG00000112232 ENSG00000198670 ENSG00000132170 PMC3782519__F1 MicroRNAs as novel immunotherapeutics ENSG00000105397 ENSG00000138798 ENSG00000168610 ENSG00000146648 ENSG00000160691 PMC3342562__F6 Schematic representation of the role of H2S in atherosclerosis ENSG00000162692 PMC8042400__F2 Biosynthesis of VLC-PUFA and VLC-SFA ENSG00000118402 ENSG00000119915 ENSG00000066322 ENSG00000197977 PMC6710239__F1 Before binding by a Hedgehog family ligand (most often Shh, but also Ihh or Dhh), Ptch1 and presumably Ptch2 maintain Smo sequestered, by a currently unknown mechanism ENSG00000143147 ENSG00000064309 ENSG00000138002 ENSG00000180447 ENSG00000106571 ENSG00000144857 ENSG00000128602 PMC9047687__F7 Whole Transcriptome Profiling of the Effects of Cadmium on the Liver of the Xiangxi Yellow Heifer ENSG00000180210 ENSG00000183760 ENSG00000169291 ENSG00000135218 ENSG00000150991 ENSG00000100979 ENSG00000164087 ENSG00000026103 PMC3191732__F1 Cyclooxygenase pathway of AA metabolism ENSG00000100473 ENSG00000226275 PMC9935926__F7 Hypoxic microenvironment in cancer: molecular mechanisms and therapeutic interventions ENSG00000102837 ENSG00000163235 ENSG00000184207 ENSG00000146648 PMC9371632__F2 Innate Immune Response and Inflammasome Activation During SARS-CoV-2 Infection ENSG00000183735 ENSG00000213928 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000130234 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000276561 ENSG00000164342 PMC4831116__F1 An overview of plant hormone signaling networks and their crosstalk in stress responses ENSG00000105722 ENSG00000136997 PMC7506139__F3 BCAAs and fatty acids regulating inflammatory signals ENSG00000162711 ENSG00000125538 ENSG00000026103 PMC9935926__F3 Hypoxic microenvironment in cancer: molecular mechanisms and therapeutic interventions ENSG00000198793 ENSG00000168036 ENSG00000168610 ENSG00000138385 PMC5724014__F6 Mechanisms of cytokine-induced dysfunction and death of insulin-secreting cells mediated by intracellular S1P ENSG00000215021 ENSG00000111537 ENSG00000002330 PMC9140571__F9 Capturing Genetic Diversity and Selection Signatures of the Endangered Kosovar Balusha Sheep Breed ENSG00000110395 ENSG00000213658 ENSG00000117091 ENSG00000010810 ENSG00000135446 ENSG00000163599 ENSG00000113263 PMC5609576__F1 Cross-talk between adipocytes, macrophages, and cancer cells modulating the tumor microenvironment ENSG00000108691 ENSG00000081041 ENSG00000137033 ENSG00000163739 ENSG00000125538 ENSG00000277943 PMC7352181__F4 Angiotensin-associated immunoinflammatory pathways in lung tumor microenvironment ENSG00000130234 PMC7352181__F3 Angiotensin-associated pathways involved on hypoxia and angiogenesis in lung tumor microenvironment ENSG00000163235 ENSG00000130234 ENSG00000138798 ENSG00000198793 PMC7352181__F2 Angiotensin-associated pathways associated with cell proliferation, invasion, and migration in lung tumor microenvironment ENSG00000130234 PMC11635172__F3 Molecular mechanisms of the immune response are involved in the progression of ALD ENSG00000148346 ENSG00000163739 ENSG00000125538 ENSG00000169429 ENSG00000136869 PMC5991421__F1 Computational model for the evaluation of complement system regulation under homeostasis, disease, and drug intervention ENSG00000039537 ENSG00000203710 PMC7352181__F1 Renin-angiotensin system, its interaction with tumor hypoxia and angiogenesis and subsequent functional impact on tumor phenotype ENSG00000130234 PMC11635172__F2 Related pathway mechanism of pyroptosis, necroptosis, and ferroptosis in the occurrence and development of ALD ENSG00000168003 ENSG00000278718 ENSG00000162711 ENSG00000151012 ENSG00000137275 ENSG00000167468 ENSG00000075420 ENSG00000265972 ENSG00000168404 ENSG00000285379 PMC5985737__F3 Relation of the studied NAFLD risk alleles to the main pathways in hepatic triglyceride partitioning ENSG00000213996 ENSG00000042832 ENSG00000100344 ENSG00000084734 ENSG00000143353 PMC5072284__F6 Activation of phenylpropanoid-biosynthesis pathway in response to cold storage ENSG00000157933 ENSG00000062485 ENSG00000084774 PMC8955828__F1 Autophagy Pathways in the Genesis of Plasmodium-Derived Microvesicles: A Double-Edged Sword? ENSG00000188554 ENSG00000057663 PMC4918128__F7 Networks of candidate cancer genes predicted by MUFFINN and their direct neighbors on HumanNet ENSG00000110799 ENSG00000168036 ENSG00000101266 ENSG00000047936 ENSG00000184056 ENSG00000166147 ENSG00000137801 ENSG00000038382 ENSG00000136891 ENSG00000095777 ENSG00000134086 ENSG00000148773 ENSG00000038427 ENSG00000037280 ENSG00000170515 ENSG00000101213 ENSG00000154928 ENSG00000155657 ENSG00000196712 ENSG00000182578 ENSG00000087245 ENSG00000160145 ENSG00000060237 ENSG00000153201 ENSG00000274442 ENSG00000101605 ENSG00000183337 ENSG00000065526 ENSG00000150672 ENSG00000135446 ENSG00000134853 ENSG00000088035 ENSG00000167986 ENSG00000106624 ENSG00000074266 ENSG00000137573 ENSG00000178691 ENSG00000149480 ENSG00000111642 PMC8616391__F1 Ferroptosis: Cancer Stem Cells Rely on Iron until “to Die for” It ENSG00000105697 ENSG00000026508 PMC3859141__F2 Molecular Pathways: Sterols and receptor signaling in cancer ENSG00000130164 ENSG00000172893 ENSG00000128602 ENSG00000146648 PMC8616391__F2 Ferroptosis: Cancer Stem Cells Rely on Iron until “to Die for” It ENSG00000168003 ENSG00000151012 ENSG00000125144 ENSG00000167468 ENSG00000111684 ENSG00000115107 PMC3859141__F1 Molecular Pathways: Sterols and receptor signaling in cancer ENSG00000130164 ENSG00000198793 ENSG00000146648 PMC3500863__F3 Pathways regulating NEKs in cell cycle control ENSG00000114670 ENSG00000149311 ENSG00000175054 ENSG00000117650 ENSG00000119408 ENSG00000166851 PMC3796213__F2 Connectivity map of NRF2-mediated oxidative stress response adapted from IPA software ENSG00000178573 ENSG00000095321 ENSG00000023909 ENSG00000079999 PMC3947043__F1 Molecular alterations and biomarkers in colorectal cancer ENSG00000120833 ENSG00000157764 ENSG00000134982 ENSG00000006283 ENSG00000020633 ENSG00000168036 ENSG00000121879 PMC2695927__F4 Bactericidal/permeability-increasing protein (BPI) in infection and inflammatory disease ENSG00000170458 ENSG00000101425 ENSG00000254550 PMC4118485__F7 Simplified schematic showing the proposed mechanism of how SEs may suppress cellular immunity and antitumor responses ENSG00000105639 ENSG00000168610 PMC7583816__F1 Diagram of proposed Pi-induced PP2A/Src/DAPK-1/TPM-3 signaling pathway ENSG00000143549 ENSG00000291971 PMC12186155__F1 Proposed mechanism of schaftoside anti-inflammation effects through the NFKB signaling pathway in LPS-induced inflammation on RAW 264 ENSG00000136869 PMC8784222__F2 COVID-19-diabetes mellitus molecular tetrahedron ENSG00000159224 ENSG00000135218 ENSG00000197635 ENSG00000130234 ENSG00000111837 ENSG00000198793 ENSG00000136869 ENSG00000198670 PMC9652018__F1 Growing Role of the BH3 Mimetic Drug Venetoclax in the Therapy of Acute Myeloid Leukemia ENSG00000100290 ENSG00000002330 ENSG00000104081 PMC8784222__F3 COVID-19-diabetes mellitus molecular tetrahedron ENSG00000130234 ENSG00000175567 PMC4415581__F7 TIGAR regulates DNA damage and repair through pentosephosphate pathway and Cdk5-ATM pathway ENSG00000149311 ENSG00000078237 PMC8733431__F7 NETME: on-the-fly knowledge network construction from biomedical literature ENSG00000105329 ENSG00000291971 ENSG00000138798 ENSG00000196154 ENSG00000181555 ENSG00000112715 ENSG00000121879 ENSG00000122194 ENSG00000118777 ENSG00000168679 ENSG00000112290 ENSG00000150782 ENSG00000082175 ENSG00000164615 ENSG00000157227 ENSG00000163914 ENSG00000136997 ENSG00000232119 ENSG00000185591 ENSG00000182718 ENSG00000087245 ENSG00000125520 ENSG00000109320 ENSG00000109321 ENSG00000168610 ENSG00000132646 ENSG00000026508 ENSG00000184371 ENSG00000100985 ENSG00000146648 PMC5763493__F3 Deubiquitylation and regulation of the immune response ENSG00000186716 ENSG00000083799 ENSG00000127191 PMC3783933__F1 IIS/TOR signaling pathway in fat body and the central nervous system of Drosophila PMC10741038__F5 PC biosynthesis in S ENSG00000173599 ENSG00000184207 PMC3845553__F1 IGF-1R as an anti-cancer target—trials and tribulations ENSG00000197081 ENSG00000198793 ENSG00000140443 PMC6407710__F7 Comparison of the phosphoketolase engineered pathway with oxidative pentose phosphate pathway ENSG00000197713 ENSG00000122966 ENSG00000134982 ENSG00000084072 ENSG00000177084 ENSG00000082212 ENSG00000062485 PMC10218067__F7 Rhein Induces Oral Cancer Cell Apoptosis and ROS via Suppresse AKT/mTOR Signaling Pathway In Vitro and In Vivo ENSG00000198793 ENSG00000123374 ENSG00000171791 PMC4972110__F1 Oncogenic addiction versus synthetic lethality to explain GSK621-induced cytotoxicity in AML ENSG00000144895 ENSG00000198793 PMC8616208__F2 Metabolic Control of Myeloid Cells in the Tumor Microenvironment ENSG00000131473 ENSG00000135218 ENSG00000042832 ENSG00000118520 ENSG00000168610 ENSG00000106546 ENSG00000079999 PMC3800594__F2 Schematic model of novel cytoprotective mechanisms in response to oxidative stress in Beta-thalassemic (Beta-thal) erythroid precursors ENSG00000128272 ENSG00000144895 PMC7960990__F6 Importance of cellular and exosomal miRNAs in mesenchymal stem cell osteoblastic differentiation ENSG00000154920 ENSG00000122966 PMC2936065__F2 The Lrp5-dependent regulation of bone formation through inhibition of tph1 expression and 5-HT synthesis in enterochromaffin cells ENSG00000162337 ENSG00000129167 PMC8534848__F2 Complex Metabolic Network Confers Immunosuppressive Functions to Myeloid-Derived Suppressor Cells (MDSCs) within the Tumour Microenvironment ENSG00000104856 ENSG00000105329 ENSG00000291971 ENSG00000197471 ENSG00000106546 PMC3545869__F7 Integration of Canonical and Noncanonical Wnt Signaling Pathways Patterns the Neuroectoderm Along the Anterior–Posterior Axis of Sea Urchin Embryos ENSG00000168036 ENSG00000125084 PMC4551213__F6 A force-sensitive signaling network involving TRPC6 and TRPM4 channels in cerebral artery smooth muscle cells ENSG00000291971 ENSG00000137672 ENSG00000124181 PMC6443256__F1 DNA sensors and related signaling pathway ENSG00000150782 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000163568 ENSG00000125538 ENSG00000163565 ENSG00000174953 ENSG00000172936 ENSG00000276561 PMC8843930__F1 Toward a Better Classification System for NK-LGL Disorders ENSG00000108691 ENSG00000198793 ENSG00000136997 ENSG00000168610 ENSG00000026103 PMC11003173__F5 Metabolic pathways of glutathione and expression profile of related genes ENSG00000178814 PMC5538798__F10 Schematic diagram summarized as a possible mechanism of action of melamine causing tubular cell injury via CSR-mediated Ca2+signaling pathway ENSG00000065833 ENSG00000105329 PMC12214129__F8 The effect of miR-1 loss on glycolytic and pentose phosphate enzymes and intermediates ENSG00000074800 ENSG00000011304 ENSG00000049239 ENSG00000141526 PMC4852795__F1 Mechanistic target of rapamycin (mTOR) signaling pathway ENSG00000177169 ENSG00000171105 ENSG00000106070 ENSG00000169047 ENSG00000155792 ENSG00000112561 PMC6468398__F1 Biogenesis and function of ribosomal RNA-derived fragments ENSG00000100234 ENSG00000092847 ENSG00000123908 PMC8688140__F1 Mechanisms of action of ivermectin against SARS-CoV-2—an extensive review ENSG00000114030 ENSG00000168610 ENSG00000122194 PMC9706722__F3 Genomic characterization of intracranial teratomas using whole genome sequencing ENSG00000166341 ENSG00000292149 ENSG00000198793 ENSG00000197905 ENSG00000164327 ENSG00000104332 ENSG00000105568 ENSG00000184916 ENSG00000121879 ENSG00000139618 ENSG00000183765 ENSG00000149311 ENSG00000122025 ENSG00000184675 ENSG00000177189 ENSG00000143801 ENSG00000136997 ENSG00000123933 ENSG00000102312 ENSG00000174197 ENSG00000077782 ENSG00000196712 PMC4937164__F1 Bile acid metabolism in the liver ENSG00000130164 ENSG00000160867 ENSG00000167910 PMC11670419__F2 BA regulates glucose homeostasis ENSG00000160867 PMC11670419__F1 Primary bile acid metabolism and secondary bile acid metabolism pathways with microbially encoded enzymes ENSG00000167910 ENSG00000115271 ENSG00000135929 PMC7826847__F3 C-CAMs involvement in radial migration during neocortical development ENSG00000177707 ENSG00000110400 ENSG00000291971 ENSG00000179242 ENSG00000170558 ENSG00000145321 ENSG00000168036 ENSG00000099942 ENSG00000173406 PMC5807065__F4 Insulin signaling and type 1 diabetes mellitus pathways ENSG00000120833 ENSG00000150907 ENSG00000169047 ENSG00000102104 PMC11911305__F2 Simplified unscaled representation of MD‐2/TLR4 complex signaling induced by extracellular LPS ENSG00000183735 ENSG00000170458 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 PMC3181488__F2 Signal-receiving cell—modulation of developmental signalling by intracellular trafficking ENSG00000089177 ENSG00000281324 ENSG00000110395 ENSG00000162337 ENSG00000128602 ENSG00000146648 PMC5465008__F2 Crosstalk between leptin signaling, cancer stem cells, histone deacetylases and microRNA ENSG00000094631 ENSG00000171720 ENSG00000119888 ENSG00000061273 ENSG00000272398 ENSG00000163517 PMC4271569__F8 The most sensitive regulations ENSG00000100285 ENSG00000242689 ENSG00000131095 ENSG00000237834 PMC5249073__F4 First Insights into the Subterranean Crustacean Bathynellacea Transcriptome: Transcriptionally Reduced Opsin Repertoire and Evidence of Conserved Homeostasis Regulatory Mechanisms ENSG00000213928 ENSG00000198793 ENSG00000131095 ENSG00000168040 ENSG00000150455 ENSG00000276561 ENSG00000143387 ENSG00000239732 ENSG00000144410 ENSG00000170458 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC5530465__F1 Metabolism of chemotherapeutic drugs-related gene polymorphisms ENSG00000035928 PMC6328967__F4 Interaction between Wnt/Beta-catenin signaling pathway and HCV core protein ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC3876077__F1 Schematic overview of the transforming growth factor (TGF)B signaling pathway ENSG00000157933 PMC5991907__F4 PARP1 regulates repair of oxidative DNA damages ENSG00000143799 ENSG00000012048 ENSG00000105486 ENSG00000132646 PMC3047755__F7 Proposed model for how Shh signaling pathway negatively regulates its mitogenic potential through Beta-arrestin 1 ENSG00000169047 ENSG00000164690 ENSG00000128602 PMC5991907__F3 PARP1 contributes to regulation of redox-related signaling pathways ENSG00000104365 ENSG00000002330 ENSG00000198793 ENSG00000118515 ENSG00000172936 ENSG00000064300 PMC5567665__F1 Integration of the tricarboxylic acid (TCA) cycle with cAMP signaling and Sfl2 pathways in the regulation of CO2 sensing and hyphal development in Candida albicans ENSG00000100412 ENSG00000146701 PMC4647060__F2 Schematic of CLCA1-driven MCM in human airways based on the current literature ENSG00000016490 PMC3200456__F1 Toxoplasma gondii effectors are master regulators of the inflammatory response ENSG00000111537 ENSG00000125538 PMC11088914__F3 The interaction of the lipid pathway with other signaling pathways for the regulation of pluripotency ENSG00000071564 ENSG00000170365 ENSG00000008710 ENSG00000134982 ENSG00000136997 ENSG00000156574 ENSG00000168036 ENSG00000135111 PMC3634439__F3 StarD7 in various cellular events in JEG-3 cells ENSG00000173599 ENSG00000084090 ENSG00000168036 ENSG00000118777 PMC3625859__F3 Regulation of angiogenesis by microRNAs (miRNAs) ENSG00000136997 ENSG00000166068 PMC2996236__F5 Pathogenesis of the complement-mediated autoinflammatory disease atypical hemolytic uremic syndrome PMC7569567__F8 Kinase inhibition in autoimmunity and inflammation ENSG00000104856 ENSG00000186716 ENSG00000173039 ENSG00000131323 ENSG00000127191 PMC10537735__F10 Modified Curcuminoid-Rich Extract Liposomal CRE-SDInhibits Osteoclastogenesis via the Canonical NFKB Signaling Pathway ENSG00000131196 ENSG00000143387 PMC11961428__F4 Proposed inflammatory mechanisms hypothesized to underlie HACE ENSG00000162711 ENSG00000171885 PMC6031075__F1 Putative model of the functions of HSPGs in CRC cells ENSG00000168036 PMC7813945__F4 JAs biosynthetic pathway and JAs signal transduction network PMC10744266__F1 Action of warfarin relevant to pharmacogene identification (further details provided in the Data Supplement) ENSG00000186115 ENSG00000115486 ENSG00000205221 ENSG00000228278 ENSG00000181019 ENSG00000255974 ENSG00000140465 PMC10910842__F2 Roles of the kinesin-2, 3, 4 family members in HCC ENSG00000101350 ENSG00000054523 PMC4611285__F1 AKT and ERK signaling pathway ENSG00000002330 ENSG00000115415 PMC11961428__F2 Transcriptional regulation of HIF induced by hypoxia, adapted from (3) ENSG00000134086 PMC8612621__F3 Crosstalk Between Parkinson's Disease and Energy Metabolism ENSG00000151657 ENSG00000171791 ENSG00000175567 PMC2996236__F2 Autoinflammatory disease regulated by IL-1B (inflammasomopathies) and NFKB ENSG00000162711 ENSG00000140368 ENSG00000125538 ENSG00000274571 ENSG00000142405 PMC7906938__F2 Immunological Mechanisms Underlying Sterile Inflammation in the Pathogenesis of Atherosclerosis: Potential Sites for Intervention ENSG00000162711 ENSG00000135218 ENSG00000163221 ENSG00000125538 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000184216 PMC4659514__F1 Proteins implicated in Parkinson’s disease (PD) maintain a healthy pool of mitochondria ENSG00000158828 PMC11722372__F2 The putative biosynthetic pathway of DAs in Aconitum plants ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC10875894__F8 VNP-shCCDC25 blocking CCDC25-NET-DNA and remodeling immunity in B16F10-bearing mice and 4T1-bearing mice ENSG00000070831 ENSG00000147419 ENSG00000188677 ENSG00000135517 PMC10910842__F3 Roles of the kinesin-5, 6 family members in HCC ENSG00000137807 ENSG00000112984 ENSG00000168036 ENSG00000137843 ENSG00000138160 PMC7049408__F1 AMPK signaling pathway: schematic model depicts the main upstream regulators and downstream effectors of AMPK ENSG00000284161 ENSG00000167658 PMC10910842__F5 Roles of the kinesin-12, 13, 14 family members in HCC ENSG00000087245 ENSG00000092621 ENSG00000122691 ENSG00000280610 ENSG00000145979 ENSG00000168036 ENSG00000140859 ENSG00000168610 ENSG00000196628 PMC7197434__F2 Pharmacologic Approaches for Adapting Proteostasis in the Secretory Pathway to Ameliorate Protein Conformational Diseases ENSG00000128272 ENSG00000100219 PMC2887678__F1 Analysis and metabolic engineering of lipid-linked oligosaccharides in glycosylation-deficient CHO cells ENSG00000101901 ENSG00000253710 ENSG00000119523 ENSG00000139133 ENSG00000159063 ENSG00000088035 ENSG00000214160 ENSG00000136908 PMC5788151__F6 Illustrating diagram for several growth factors and signaling molecules that regulate different stages of satellite cells ENSG00000009709 ENSG00000019991 ENSG00000111049 PMC10486640__F8 Identification of the expression of key genes of the TLR signaling pathway ENSG00000168040 ENSG00000150455 ENSG00000276561 ENSG00000143387 ENSG00000126218 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000136997 ENSG00000136869 ENSG00000172936 ENSG00000175104 ENSG00000164342 PMC7923093__F5 Regulatory pathway of differently expressed miRNAs ENSG00000182901 ENSG00000185608 ENSG00000101079 ENSG00000075975 ENSG00000167910 ENSG00000109606 ENSG00000292211 ENSG00000176635 ENSG00000274348 ENSG00000164305 ENSG00000274542 ENSG00000156269 ENSG00000165383 ENSG00000182489 ENSG00000152154 ENSG00000148229 ENSG00000103023 ENSG00000141753 ENSG00000152208 ENSG00000184203 ENSG00000111269 ENSG00000122862 ENSG00000148965 ENSG00000115091 ENSG00000176624 ENSG00000197375 ENSG00000164163 ENSG00000115648 ENSG00000221818 ENSG00000169583 ENSG00000112697 ENSG00000093217 ENSG00000138942 ENSG00000152291 ENSG00000182389 PMC8836259__F10 Oncogenic Mutation BRAF V600E Changes Phenotypic Behavior of THLE-2 Liver Cells through Alteration of Gene Expression ENSG00000169248 ENSG00000187608 ENSG00000137033 ENSG00000163739 ENSG00000185745 ENSG00000166670 ENSG00000168961 ENSG00000162654 ENSG00000150782 ENSG00000169245 ENSG00000134321 ENSG00000149968 ENSG00000125538 ENSG00000100985 PMC5787431__F2 KSHV LANA upregulates the expression of epidermal growth factor like domain 7 to promote angiogenesis ENSG00000107018 ENSG00000105472 ENSG00000151640 ENSG00000138798 ENSG00000120088 ENSG00000133863 ENSG00000177551 ENSG00000168811 ENSG00000274513 ENSG00000136826 ENSG00000006837 ENSG00000163914 ENSG00000188596 ENSG00000164627 ENSG00000146555 ENSG00000041515 ENSG00000215474 ENSG00000288263 ENSG00000150275 ENSG00000100625 ENSG00000087116 ENSG00000198947 ENSG00000182742 ENSG00000152495 ENSG00000157423 ENSG00000089041 ENSG00000187848 ENSG00000164736 ENSG00000063660 ENSG00000117601 ENSG00000172889 ENSG00000265203 PMC7663396__F1 Signaling pathways leading to signal transducer and activator of transcription 3 (STAT3) activation ENSG00000291971 ENSG00000198793 ENSG00000146648 PMC9572668__F3 Molecular Mechanisms and Health Benefits of Ghrelin: A Narrative Review ENSG00000162711 ENSG00000125538 ENSG00000136869 ENSG00000121853 PMC7569567__F2 Kinase inhibition in autoimmunity and inflammation ENSG00000138378 ENSG00000111537 ENSG00000099985 ENSG00000105397 ENSG00000115415 ENSG00000145777 ENSG00000128342 ENSG00000105639 ENSG00000168610 ENSG00000162892 ENSG00000142224 PMC6625878__F1 Schematic figure summarizing the HIF pathway and the transcriptional regulation by HIF of genes related to angiogenesis, metabolism, survival/proliferation, metastasis, stemness, and the ECM ENSG00000134086 ENSG00000138764 ENSG00000148400 ENSG00000163235 ENSG00000148926 ENSG00000026508 ENSG00000112715 ENSG00000154188 ENSG00000118777 ENSG00000121966 PMC2921023__F7 Effective targeting of STAT5-mediated survival in myeloproliferative neoplasms using ABT-737 combined with rapamycin ENSG00000033327 ENSG00000291971 ENSG00000198793 PMC7234907__F1 MET receptor tyrosine kinase engages intracellular molecular signaling pathways and controls neuronal morphological development ENSG00000019991 ENSG00000106683 ENSG00000070831 ENSG00000198793 ENSG00000197386 PMC3193404__F1 NFKB signaling pathways initiated by TLR4, TCR, TNF receptor 1, CD40 and genotoxic stress ENSG00000149311 ENSG00000119878 ENSG00000136869 ENSG00000127191 PMC10608541__F13 Pathways and localization of astaxanthin biosynthesis and esterification in Haematococcus algae ENSG00000197429 ENSG00000285482 ENSG00000062282 ENSG00000026103 PMC9651967__F7 Integrated proteomics and phosphoproteomics revealed druggable kinases in neoadjuvant chemotherapy resistant tongue cancer ENSG00000186395 ENSG00000070831 ENSG00000167768 ENSG00000149269 ENSG00000125733 ENSG00000067606 ENSG00000118515 ENSG00000126777 ENSG00000184363 ENSG00000196914 ENSG00000166484 PMC7501262__F4 NLRP3 inflammasome in endothelial dysfunction ENSG00000162711 ENSG00000125538 ENSG00000189403 ENSG00000172936 ENSG00000162692 ENSG00000175104 ENSG00000184216 ENSG00000115594 PMC3772111__F4 Computational models of the JAK1/2-STAT1 signaling ENSG00000115415 ENSG00000125347 PMC6204425__F3 Some regulator genes in the eu-/pheomelanin synthesis metabolism ENSG00000157404 ENSG00000133116 ENSG00000104044 ENSG00000101440 ENSG00000135903 ENSG00000115138 ENSG00000080166 ENSG00000164175 PMC4024346__F1 The ERK1/2 MAPK signaling network controlled by receptor tyrosine kinases and Ras ENSG00000094631 ENSG00000002330 ENSG00000095015 PMC11594976__F7 Differential expression of hormone signaling pathway genes in PhARF5- and PhARF19a-silenced petunias ENSG00000110934 ENSG00000221818 PMC6831866__F20 Continuation of the processes described in A ENSG00000132906 ENSG00000164305 ENSG00000167419 PMC7501262__F5 NLRP3 inflammasome in endothelial dysfunction ENSG00000162711 PMC11055549__F3 Construction of the prognostic target-ingredient network ENSG00000163399 ENSG00000178999 ENSG00000087586 ENSG00000145386 ENSG00000166851 ENSG00000167900 ENSG00000138160 ENSG00000186298 ENSG00000134057 ENSG00000291814 ENSG00000135446 ENSG00000112742 ENSG00000253729 ENSG00000175305 PMC11760113__F1 Metabolism of glutamine between normal cells and cancer cells ENSG00000125166 ENSG00000135423 ENSG00000151012 ENSG00000182902 ENSG00000111371 ENSG00000103257 ENSG00000166123 PMC2738707__F1 Regulatory pathways in hepcidin expression ENSG00000187045 ENSG00000105697 ENSG00000105698 ENSG00000168610 PMC4196943__F5 Dissecting the Transcriptional Response to Elicitors in Vitis vinifera Cells ENSG00000205221 ENSG00000062485 PMC7489940__F5 PI3K-AKT signing pathway ENSG00000132906 ENSG00000168209 ENSG00000002330 ENSG00000119535 ENSG00000105401 ENSG00000198793 ENSG00000134308 ENSG00000108342 ENSG00000213341 ENSG00000141564 ENSG00000171791 ENSG00000121879 ENSG00000107175 ENSG00000160741 ENSG00000177455 ENSG00000103479 ENSG00000136997 ENSG00000040199 ENSG00000123374 ENSG00000160447 PMC7363530__F1 Genetic pathways in nonalcoholic fatty liver disease (NAFLD) ENSG00000213996 ENSG00000042832 ENSG00000170509 ENSG00000011198 ENSG00000138823 ENSG00000100344 ENSG00000084734 PMC6627586__F1 Scheme of copper and silver distribution in a mammalian cell ENSG00000138495 ENSG00000123191 ENSG00000177556 PMC6565468__F1 Convergence of Developmental Origins and Oncogenic Pathways in Malignant Brain Tumors ENSG00000019991 ENSG00000138336 ENSG00000134982 ENSG00000135446 ENSG00000138798 ENSG00000198793 ENSG00000173599 ENSG00000123374 ENSG00000205927 ENSG00000105810 ENSG00000146648 ENSG00000196712 PMC6558092__F1 PD-1 signaling pathway in T cells.When engaged with a ligand, PD-1 becomes phosphorylated at its cytoplasmic tyrosine residue, leading to binding of protein tyrosine phosphatases (PTPs), such as SHP2 ENSG00000291603 ENSG00000156127 PMC9482157__F9 VEGFA promotes the occurrence of PLA2R-associated idiopathic membranous nephropathy by angiogenesis via the PI3K/AKT signalling pathway ENSG00000153094 ENSG00000176248 ENSG00000099194 ENSG00000112715 ENSG00000140464 PMC3087179__F5 IL-4R Drives Dedifferentiation, Mitogenesis and Metastasis in Rhabdomyosarcoma ENSG00000123496 ENSG00000131724 PMC3851989__F2 The second module identified by iMCMC and the corresponding known pathway in the GBM data ENSG00000135446 ENSG00000135452 PMC4899284__F1 Folate-Mediated One-Carbon Metabolism ENSG00000284320 ENSG00000228716 ENSG00000065911 ENSG00000100714 ENSG00000163738 PMC2943518__F7 Diagram of a putative LPS-induced PTP/LITAF/TNF signaling pathway ENSG00000291470 ENSG00000136869 ENSG00000189067 PMC4765525__F1 Wnt signaling pathway from KEGG ENSG00000156076 ENSG00000095739 ENSG00000100387 ENSG00000134982 ENSG00000167941 ENSG00000113558 ENSG00000127948 PMC5375627__F5C Induction of glycolytic and tricarboxylic acid cycle enzymes by M-CSF and GM-CSF ENSG00000160883 ENSG00000108515 ENSG00000067057 ENSG00000117118 ENSG00000105953 ENSG00000172340 ENSG00000131828 ENSG00000101365 ENSG00000143252 ENSG00000074800 ENSG00000100412 ENSG00000114268 ENSG00000146701 ENSG00000091140 ENSG00000159399 ENSG00000062485 PMC6328967__F5 Interaction between COX-2 signaling pathway and HCV core protein ENSG00000086991 PMC7730176__F3 Estrogen and anti-estrogen signaling in glioblastoma ENSG00000198793 ENSG00000168610 PMC11849288__F4 Expression profiles of genes in starch and sucrose metabolism pathway ENSG00000111816 PMC3323875__F3 Feedback inhibition mediated by the PI3K/AKT/mTOR pathway ENSG00000065361 ENSG00000106070 ENSG00000169047 ENSG00000140443 PMC4967146__F1 Regulation of mRNA translation initiation by the mechanistic target of rapamycin complex 1(mTORC1) signaling pathway PMC6678402__F2 Illustration of proposed mechanisms of stem cell therapy in rescuing ischemia-reperfusion induced acute kidney injury ENSG00000178573 ENSG00000105656 ENSG00000135605 ENSG00000026103 PMC4899284__F2 The de novo thymidylate synthesis pathway as a nuclear multienzyme complex at sites of DNA replication ENSG00000228716 ENSG00000100714 PMC7108857__F10 Working model of FMDV 3A regulation of the G3BP1-mediated RLH signaling pathway ENSG00000183735 ENSG00000175489 ENSG00000175104 PMC9450830__F4 Human arginase 1, a Jack of all trades? PMC9981633__F1 Targeting matrix metalloproteases in diabetic wound healing ENSG00000169245 ENSG00000107562 ENSG00000161921 ENSG00000148400 ENSG00000138755 PMC11274428__F1 The PI3K/Akt/mTOR Axis in Head and Neck Squamous Cell Carcinoma ENSG00000198793 ENSG00000155792 ENSG00000167965 PMC3466369__F1 Emerging Roles for Cholesterol and Lipoproteins in Lung Disease ENSG00000130164 ENSG00000136869 ENSG00000160179 PMC6715851__F2 Differences in the carbon flux distribution in oleaginous rhodococci under nitrogen-rich and nitrogen-poor (TAG accumulation) conditions ENSG00000132693 ENSG00000026103 PMC7603577__F11 AGE-RAGE signaling pathway in diabetic complications in the treatment of gout and hyperuricemia with plantain PMC7603577__F10 TNF signaling pathway in the treatment of gout and hyperuricemia with plantain ENSG00000226275 ENSG00000102871 ENSG00000082512 ENSG00000157625 ENSG00000100985 ENSG00000168040 ENSG00000127191 PMC3322159__F8 JC Virus T-Antigen Regulates Glucose Metabolic Pathways in Brain Tumor Cells ENSG00000134057 ENSG00000159399 PMC3713637__F4 Transcriptional regulation network centered on SP1 involves many genes of interest from pathways enriched in memory impairment ENSG00000152495 ENSG00000077522 ENSG00000010810 ENSG00000149782 ENSG00000150093 ENSG00000185591 ENSG00000143933 ENSG00000182621 ENSG00000137841 PMC6137035__F7 Pathway schematic ENSG00000134086 ENSG00000168610 PMC11670419__F3 FXR signaling in diabetic nephropathy ENSG00000042832 ENSG00000197959 ENSG00000168036 ENSG00000026103 PMC6114234__F1 Synthesis, metabolism and anticancer mechanism of vitamin D ENSG00000111012 ENSG00000105516 ENSG00000019186 ENSG00000198793 ENSG00000168036 ENSG00000135929 PMC7430807__F2 Metabocentric view of cardiac remodeling ENSG00000179862 ENSG00000172216 ENSG00000198793 PMC1800873__F1 Progression pathway network with w = 0.8, E = 0.8 and the LH algorithm PMC7565554__F4 mTORC1 inhibits various steps of autophagy ENSG00000177169 ENSG00000110497 ENSG00000123395 ENSG00000198382 ENSG00000126775 ENSG00000148572 ENSG00000112561 PMC5374322__F3 Relationships among miRNAs and canonical Wnt signaling, metastasis, and tumor-initiating cells ENSG00000183734 ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000133961 PMC5374322__F2 Genes frequently mutated in colorectal cancer and their relationships with miRNAs ENSG00000136997 ENSG00000168036 ENSG00000187772 PMC7565554__F2 Transcription factors downstream of TORC1, input linked to their action and cellular processes affected ENSG00000128272 ENSG00000198793 ENSG00000155792 ENSG00000112561 ENSG00000167965 PMC5374322__F1 Step-wise tumorigenesis in colorectal cancer ENSG00000157764 ENSG00000134982 ENSG00000168036 ENSG00000121879 PMC3565105__F1 Hypothetical model illustrates the E2-ERA signaling pathway involving both genomic and extranuclear signaling pathways ENSG00000101751 ENSG00000291971 ENSG00000166169 ENSG00000141456 PMC7565554__F1 TORC1 and TORC2 subunits and processes controlled by the complexes ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 ENSG00000186654 PMC4831796__F7 Inhibition of Phosphatase Activity Follows Decline in Sulfatase Activity and Leads to Transcriptional Effects through Sustained Phosphorylation of Transcription Factor MITF ENSG00000136235 PMC3233666__F1 Adaptation of endothelial cells to inflammatory stimuli and hypoxia ENSG00000104856 ENSG00000134086 ENSG00000136869 ENSG00000131323 ENSG00000162692 ENSG00000121966 PMC8006752__F1 BAP1 nuclear and cytoplasmic physiologic activities ENSG00000012048 ENSG00000163930 ENSG00000147162 ENSG00000171456 ENSG00000151012 ENSG00000143970 ENSG00000156026 ENSG00000141568 ENSG00000051180 ENSG00000141431 ENSG00000128908 ENSG00000164916 PMC9023792__F1 Emerging Role of Hedgehog Signaling in Viral Infections ENSG00000106571 ENSG00000173040 ENSG00000136997 ENSG00000171791 ENSG00000128602 PMC10864729__F6 Predicted downstream pathway of MIR17HG ENSG00000213949 ENSG00000086200 PMC9023792__F2 Emerging Role of Hedgehog Signaling in Viral Infections ENSG00000106571 ENSG00000128602 PMC8014416__F6 KEGG pathway analysis on three up-regulated DEGs ENSG00000177455 ENSG00000103479 ENSG00000111537 ENSG00000187720 ENSG00000186716 ENSG00000198793 ENSG00000113558 ENSG00000174136 PMC6205963__F1 Fibroblast of Growth Factor (FGF) signaling activation and regulation ENSG00000070388 ENSG00000118972 ENSG00000070193 ENSG00000033327 ENSG00000105550 ENSG00000102466 ENSG00000130147 ENSG00000078579 ENSG00000156427 ENSG00000140285 ENSG00000164690 ENSG00000114315 ENSG00000114279 PMC2780838__F1 The complement cascade ENSG00000039537 ENSG00000113600 ENSG00000291559 ENSG00000203710 ENSG00000244731 ENSG00000166278 ENSG00000182326 ENSG00000236625 PMC7658718__F7 Schematic model illustatrating the redox regulation of PD-L1 expression through growth factor signaling ENSG00000138798 ENSG00000077782 ENSG00000146648 PMC3536347__F2 Pharamcologic activators and enhancers of the Wnt/Beta-catenin signaling pathway and known interactions with pathway components (see for references) ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 PMC3536347__F1 Pharmacologic inhibitors of the Wnt/Beta-catenin signaling pathway and known interactions with pathway components (see for references) ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000106483 ENSG00000177283 ENSG00000155760 ENSG00000173273 PMC6445295__F1 Analysis of human inner ear transcriptome over-layed on a generic human neurotrophin signaling pathway PMC2819352__F6 Relationship of GPAT4 to other enzymes in the pathway of de novo glycerolipid synthesis ENSG00000173599 ENSG00000158669 ENSG00000198670 ENSG00000186281 PMC6595574__F2 Signaling pathway and inhibitors of inflammasomes ENSG00000162711 ENSG00000185515 ENSG00000125538 PMC5378756__F1 The activation, amplification and regulation of the complement system ENSG00000022267 PMC2863215__F2 Regulation of mTORC signaling networks ENSG00000011566 ENSG00000138798 ENSG00000006451 ENSG00000169047 ENSG00000198793 ENSG00000155792 ENSG00000146648 PMC8779519__F3 Hidradenitis Suppurativa and Comorbid Disorder Biomarkers, Druggable Genes, New Drugs and Drug Repurposing—A Molecular Meta-Analysis ENSG00000148346 ENSG00000101751 ENSG00000111537 ENSG00000102871 ENSG00000111837 ENSG00000105656 ENSG00000084110 ENSG00000131323 ENSG00000168040 ENSG00000166169 PMC8779519__F2 Hidradenitis Suppurativa and Comorbid Disorder Biomarkers, Druggable Genes, New Drugs and Drug Repurposing—A Molecular Meta-Analysis ENSG00000183625 ENSG00000197272 ENSG00000274736 ENSG00000187266 ENSG00000121807 ENSG00000064300 ENSG00000121966 ENSG00000163702 ENSG00000145623 ENSG00000135960 ENSG00000122756 ENSG00000117400 ENSG00000181374 ENSG00000147896 ENSG00000164400 ENSG00000288185 ENSG00000056736 ENSG00000112486 ENSG00000026103 ENSG00000189377 ENSG00000139193 ENSG00000159128 ENSG00000099985 ENSG00000242689 ENSG00000145777 ENSG00000054967 ENSG00000162594 ENSG00000186810 ENSG00000226275 ENSG00000161921 ENSG00000108700 ENSG00000126353 ENSG00000243646 ENSG00000016402 PMC3296254__F5 Arginine metabolic network ENSG00000091704 ENSG00000081181 ENSG00000118520 ENSG00000158516 PMC5432965__F2 Microarray profiling of 467 human GBMs discovered that polo-like kinase 1 (PLK1) was highly expressed in these tumors and that it clustered with the proliferative subtype ENSG00000065613 ENSG00000108055 ENSG00000134982 ENSG00000177084 ENSG00000117399 PMC8779519__F4 Hidradenitis Suppurativa and Comorbid Disorder Biomarkers, Druggable Genes, New Drugs and Drug Repurposing—A Molecular Meta-Analysis ENSG00000131095 ENSG00000127948 PMC3943829__F1 A scheme of metabolic pathway for cholesterol biogenesis ENSG00000110921 ENSG00000172893 ENSG00000149809 PMC8814461__F2 Emerging Roles of Circular RNAs in the Chemoresistance of Gastrointestinal Cancer ENSG00000012048 ENSG00000168283 ENSG00000125398 ENSG00000198793 ENSG00000168036 ENSG00000171791 ENSG00000168610 PMC5920642__F3 Cell proliferation and negative apoptosis regulation in the uterine leiomyoma ENSG00000165280 ENSG00000171791 PMC9331212__F1 Precision Medicine Highlights Dysregulation of the CDK4/6 Cell Cycle Regulatory Pathway in Pediatric, Adolescents and Young Adult Sarcomas ENSG00000112576 ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 ENSG00000118971 ENSG00000175305 PMC8740161__F3 Synergistic effects of methyl 2-cyano-3,11-dioxo-18beta-olean-1,-12-dien-30-oate and erlotinib on erlotinib-resistant non-small cell lung cancer cells ENSG00000094804 ENSG00000167513 ENSG00000132646 ENSG00000115942 ENSG00000163918 ENSG00000135336 ENSG00000106628 ENSG00000177084 PMC12197700__F2 Disruption of the SA signaling pathway by viral proteins ENSG00000166278 ENSG00000184900 PMC12197700__F1 Signal transduction in the SA signaling pathway ENSG00000184900 PMC6143874__F2 Binding of growth factors and hormones to their respective receptors or ligands serves a pivotal role in Beta-cell proliferation ENSG00000105329 ENSG00000172780 ENSG00000150907 ENSG00000139515 ENSG00000123374 ENSG00000160741 PMC7814174__F3 GDF15 and FGF21 as mitokines in the diurnal regulation of energy balance ENSG00000105550 ENSG00000198576 ENSG00000130513 PMC6143874__F1 Binding of PDGF, GLP-1, IGF-1 and BTC to their respective receptors serves an important role in Beta-cell proliferation ENSG00000134982 ENSG00000135446 ENSG00000150907 ENSG00000139515 ENSG00000168036 ENSG00000118971 ENSG00000140443 PMC6143874__F3 JAK-STAT signaling in tandem with multiple cytokines and hormones participates in the regulation of Beta-cells ENSG00000112576 ENSG00000135446 ENSG00000118971 PMC6230558__F6 TRPV4 activation caused oligodendrocyte apoptosis and demyelination ENSG00000125538 PMC8669714__F3 Cell Survival and Cell Death at the Intersection of Autophagy and Apoptosis: Implications for Current and Future Cancer Therapeutics ENSG00000177169 ENSG00000100290 ENSG00000123395 ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC5159445__F2 MetaCore Immune response_IL-17 signaling pathway ENSG00000112116 ENSG00000108691 ENSG00000108688 ENSG00000185591 ENSG00000175104 ENSG00000115009 ENSG00000163702 PMC7464784__F2 Illustrating the metabolic components contributing to drug resistance and drugs to overcome the resistance ENSG00000284774 ENSG00000160867 ENSG00000198793 ENSG00000163064 ENSG00000172936 ENSG00000136869 ENSG00000146648 ENSG00000159399 ENSG00000292210 PMC7464784__F1 An illustration of glucose metabolism leading from the glycolytic pathway to the tricarboxylic acid cycle (TCA) and electron transport chain (ETC) ENSG00000180210 ENSG00000175054 ENSG00000205221 PMC9286619__F1 The androgen receptor in the pathogenesis of obesity and its utility as a target for obesity treatments ENSG00000291971 ENSG00000146648 PMC8442523__F2 TRPV1 in the pain pathway: similarities and differences between desensitization by agonists and blockade by antagonists ENSG00000078747 ENSG00000196689 PMC6064203__F4 Integrative machine learning analysis of multiple gene expression profiles in cervical cancer ENSG00000170860 ENSG00000156970 ENSG00000198743 ENSG00000135476 ENSG00000145386 ENSG00000184432 ENSG00000177084 PMC6064203__F3 Integrative machine learning analysis of multiple gene expression profiles in cervical cancer ENSG00000169814 ENSG00000198300 ENSG00000177600 ENSG00000215788 PMC8064071__F3 Scheme of the central carbon metabolism and carotenogenesis in C ENSG00000197713 ENSG00000197429 PMC6022934__F8 Urea cycle and pyrimidine de novo biosynthesis pathway ENSG00000036473 ENSG00000102967 ENSG00000084774 PMC4309523__F5 An example from dGCspALL2 ENSG00000011600 ENSG00000163131 ENSG00000110777 ENSG00000213402 ENSG00000156738 ENSG00000137265 ENSG00000126353 ENSG00000121807 ENSG00000111348 ENSG00000010671 ENSG00000168685 PMC2315681__F8 Leptin's roles in the endocardial cushion ENSG00000087245 ENSG00000157227 PMC3181269__F1 Mammalian Triacylglycerol Metabolism: Synthesis, Lipolysis and Signaling ENSG00000131446 ENSG00000168282 ENSG00000173599 ENSG00000158669 ENSG00000285482 ENSG00000198670 ENSG00000160216 ENSG00000186281 ENSG00000062282 PMC2762943__F1 Epidermal growth factor receptor (EGFR) pathway ENSG00000163235 ENSG00000138798 ENSG00000146648 PMC11635611__F3 Crosstalk among microglia and astrocytes with neurons ENSG00000169245 ENSG00000162711 ENSG00000186810 PMC2762943__F3 P53 pathway ENSG00000136997 ENSG00000026103 PMC11635611__F2 Morphine tolerance-related signaling pathways inside microglia ENSG00000162711 ENSG00000136869 ENSG00000146648 PMC5323371__F3 Utilizing a combination of immunoprecipitation (IP) and tandem mass spectrometry (MS) protein identification (ID), complemented by gene expression analysis, a comprehensive Ang-(1-7) stimulated Mas1 receptor signaling pathway was generated ENSG00000122025 ENSG00000070831 ENSG00000198793 ENSG00000163914 ENSG00000285485 ENSG00000155974 ENSG00000131196 ENSG00000184304 PMC8669714__F2 Cell Survival and Cell Death at the Intersection of Autophagy and Apoptosis: Implications for Current and Future Cancer Therapeutics ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000126775 ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC7261637__F8 Model depicts the proposed role of HPSE in promoting stemness ENSG00000173083 PMC8669714__F1 Cell Survival and Cell Death at the Intersection of Autophagy and Apoptosis: Implications for Current and Future Cancer Therapeutics ENSG00000100290 ENSG00000137275 ENSG00000102871 ENSG00000056558 ENSG00000120868 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC2668954__F4 Mechanotransduction gone awry ENSG00000285109 ENSG00000163914 PMC3797199__F1 Aryl Hydrocarbon Receptor Promotes RORGt+ ILCs and Controls Intestinal Immunity and Inflammation ENSG00000157404 ENSG00000125538 ENSG00000111321 ENSG00000106546 PMC5650460__F1 Dual roles of yes-associated protein (YAP) in colorectal cancer ENSG00000198793 ENSG00000164690 ENSG00000146648 PMC2849843__F2 Schematic presentation of Akt-mTOR signaling ENSG00000198793 ENSG00000164327 PMC8063392__F5 LCK pathway regulates cisplatin resistance in endometrioid tumors. Downstream of CD55, LCK stimulates expression of DNA repair genes, leading to cisplatin resistance ENSG00000169071 ENSG00000196352 PMC2849843__F1 Schematic presentation of PI3K-Akt signaling ENSG00000002330 ENSG00000005882 PMC11634819__F8 Schematic diagram illustrating the signaling pathway through which A‐MG influences hypertension, hypertension‐associated vascular remodeling, and changes in uric acid levels ENSG00000130234 PMC7701524__F10 Schematic illustration of the potential molecular mechanism of miR‐148a‐3p as a tumour suppressor in PC ENSG00000168036 ENSG00000125084 PMC7904608__F2 Metabolic regulation of trained immunity in HSCs ENSG00000160883 ENSG00000067057 ENSG00000113161 PMC7564431__F6 STRING protein interaction network of 61 out of 652 genes targeted by the selected miRNAs and directly involved in the breast cancer KEGG pathway (hsa05224) ENSG00000134982 ENSG00000188064 ENSG00000168036 ENSG00000108443 ENSG00000100485 ENSG00000121879 ENSG00000102678 ENSG00000124762 ENSG00000175634 ENSG00000112242 ENSG00000163251 ENSG00000074181 ENSG00000136997 ENSG00000105810 ENSG00000177283 ENSG00000077782 ENSG00000139687 ENSG00000140443 ENSG00000154342 ENSG00000157764 ENSG00000148400 ENSG00000116717 ENSG00000117020 ENSG00000134574 ENSG00000135446 ENSG00000177606 ENSG00000104290 ENSG00000161202 ENSG00000146648 PMC3722958__F2 The suggested interplay between natural killer (NK), CD4+ T, B cells, and polymorphonuclear cells (PMN) during pemphigus pathogenesis ENSG00000162889 ENSG00000134757 ENSG00000114738 PMC3722958__F1 P38 MAPK in the induction of pemphigus vulgaris (PV) ENSG00000162889 ENSG00000134757 ENSG00000134760 ENSG00000114738 PMC9047385__F1 Phytochemicals targeting Toll-like receptors 4 (TLR4) in inflammatory bowel disease ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC6073671__F1 Silver nanoparticles on the cell stress response pathways ENSG00000128272 ENSG00000100219 ENSG00000171791 PMC2957893__F3 Genes in one pathway have complex “net” interactions, which should be taken into consideration when analyzing proteomics/genomic data ENSG00000149311 ENSG00000135446 ENSG00000132646 ENSG00000105810 PMC5190062__F8 ER stress in temozolomide-treated glioblastomas interferes with DNA repair and induces apoptosis ENSG00000128272 ENSG00000170430 ENSG00000051180 PMC7680862__F1 Mitochondria-associated ER membranes and cell physiology ENSG00000162711 ENSG00000168958 ENSG00000119737 ENSG00000156026 ENSG00000198793 ENSG00000265972 ENSG00000166278 ENSG00000140464 ENSG00000214253 PMC6803036__F2 Secreted IgM: New Tricks for an Old Molecule ENSG00000186716 ENSG00000173599 ENSG00000145321 ENSG00000105656 PMC2866141__F4 Molecular Basis of Pulmonary Alveolar Proteinosis ENSG00000170458 ENSG00000172005 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC9168125__F1 Galectin Family Members: Emerging Novel Targets for Lymphoma Therapy? ENSG00000288335 ENSG00000185591 PMC6144927__F1 TGFB signaling maintains homeostasis between the proliferation and apoptosis of normal epithelial cells by Smads or other Smad-independent downstream pathways ENSG00000136997 ENSG00000100985 PMC8904278__F3 Metabolic Rewiring by NRF2 ENSG00000168003 ENSG00000151012 ENSG00000092621 ENSG00000167468 ENSG00000135069 ENSG00000146733 ENSG00000023909 PMC6017900__F7 Signaling pathways for flaccidoxide-13-acetate in bladder cancer ENSG00000087245 ENSG00000198793 PMC8754418__F1 Congenital Micropenis: Etiology And Management ENSG00000155011 ENSG00000168036 ENSG00000185591 PMC4905404__F2 Regulators of phenotypic plasticity ENSG00000019991 ENSG00000026508 ENSG00000118777 PMC10789540__F5 IFITM3-mediated activation of TRAF6/MAPK/AP-1 pathways induces acquired TKI resistance in clear cell renal cell carcinoma ENSG00000142089 ENSG00000175104 ENSG00000184216 PMC2880413__F2 Networks for (A) Biological network (B) Network MDL approach (C) PMDL approach The performance on the algorithms is performed on a biological data set ENSG00000108055 ENSG00000004897 ENSG00000117399 PMC8639566__F1 Sensing Stemness ENSG00000164430 ENSG00000088888 ENSG00000175104 ENSG00000276561 PMC3874211__F4 Network pathway analysis integrated the majority of proteins identified as changed on 2DE (), as shown in but did not include S-methyl-5`thioadenosine phosphorylase, and lamin B1 because of low scoring ENSG00000100519 ENSG00000163956 ENSG00000103266 ENSG00000157851 ENSG00000105329 ENSG00000110244 ENSG00000165280 ENSG00000120437 ENSG00000092199 ENSG00000284254 ENSG00000197386 ENSG00000256646 ENSG00000091140 ENSG00000115419 ENSG00000114115 ENSG00000142552 PMC4979452__F7 Cell adhesion ENSG00000038382 ENSG00000149269 ENSG00000010810 ENSG00000026508 ENSG00000168036 ENSG00000076706 ENSG00000131095 ENSG00000154721 ENSG00000154654 ENSG00000104368 PMC7805339__F1 Current understanding of the mechanism of action of luspatercept ENSG00000135414 ENSG00000130283 ENSG00000266524 ENSG00000184344 PMC4979452__F6 Protein kinase A (PKA) signaling pathway ENSG00000125787 ENSG00000291972 ENSG00000068976 ENSG00000180772 ENSG00000117152 ENSG00000168398 ENSG00000151617 ENSG00000155903 ENSG00000100739 ENSG00000102468 PMC3820535__F7 Modeling Integrated Cellular Machinery Using Hybrid Petri-Boolean Networks ENSG00000070831 PMC4979452__F8 Cytoskeleton remodeling and axonal transport ENSG00000006607 ENSG00000145147 ENSG00000076928 ENSG00000100285 ENSG00000070831 ENSG00000196358 ENSG00000204843 ENSG00000169783 ENSG00000266028 ENSG00000131095 ENSG00000121966 PMC1894940__F5 Inhibition of COX-2 modulates multiple functional pathways during acute inflammation and pain ENSG00000179148 ENSG00000179477 ENSG00000164120 ENSG00000179593 PMC3296254__F7 Lysine biosynthetic pathway ENSG00000011143 PMC4979452__F3 Ion homeostasis ENSG00000183691 ENSG00000099940 ENSG00000138172 ENSG00000001626 ENSG00000137731 PMC9355504__F1 Focus on the tumor microenvironment: A seedbed for neuroendocrine prostate cancer ENSG00000084093 ENSG00000163235 ENSG00000198793 ENSG00000288335 ENSG00000164266 ENSG00000168610 PMC4979452__F2 Mitogen-activated protein kinase (MAPK) signaling pathway ENSG00000162889 ENSG00000002330 ENSG00000138798 ENSG00000115904 ENSG00000155903 ENSG00000162772 ENSG00000127191 ENSG00000100485 ENSG00000115290 ENSG00000122025 ENSG00000066468 ENSG00000157557 ENSG00000076928 ENSG00000106070 ENSG00000280477 ENSG00000185591 ENSG00000146648 ENSG00000123268 PMC6678596__F1 Representation of the main DNA repair pathways involved in platinum salts-induced DNA damage ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000083093 ENSG00000051180 ENSG00000138385 ENSG00000139618 PMC5560156__F1 Schematic overview of the molecular network involved in VSV oncoselectivity ENSG00000183735 ENSG00000130164 ENSG00000198793 PMC4979452__F5 JAK-STAT (Janus kinase/signal transducers and activators of transcription) pathway ENSG00000111537 ENSG00000099985 ENSG00000115415 ENSG00000163235 ENSG00000138798 ENSG00000123609 ENSG00000180772 ENSG00000112039 ENSG00000168610 ENSG00000146648 ENSG00000062485 PMC4979452__F4 PI3K-AKT (phosphatidylinositol-4,5-bisphosphate 3-kinase-AKT) signaling pathway ENSG00000149089 ENSG00000066468 ENSG00000076928 ENSG00000102871 ENSG00000146648 ENSG00000064300 ENSG00000140443 PMC3539919__F2 Simplified carbon metabolic network PMC6032252__F1 The tumor microenvironment on myeloid cell differentiation and metabolism ENSG00000019991 ENSG00000183735 ENSG00000163220 ENSG00000128342 PMC12103044__F10 Examples of eExo for promoting chronic wound healing ENSG00000198793 ENSG00000136869 ENSG00000096717 ENSG00000142082 ENSG00000168610 ENSG00000166135 PMC8349099__F1 Calcium signaling in hepatitis B virus infection and its potential as a therapeutic target ENSG00000135218 ENSG00000167323 ENSG00000291971 ENSG00000293604 ENSG00000078668 ENSG00000156026 ENSG00000171791 ENSG00000164305 PMC3048914__F6 Differentially expressed genes in the MICs as compared to NSPCs ENSG00000151702 ENSG00000242689 ENSG00000138798 ENSG00000113140 ENSG00000175832 ENSG00000168036 ENSG00000185591 ENSG00000146648 ENSG00000026103 PMC4937866__F13 AhRR repression on AhR activity and the consequences in endpoints ENSG00000106546 PMC6563055__F4 NOX4-related mechanisms in thyroid carcinogenesis ENSG00000086991 PMC3668263__F3 Wnt signaling pathways ENSG00000070831 ENSG00000100592 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC3668263__F2 LRRK2 regulates cell biological functions important for neurogenesis ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC3986808__F2 Copper is passed (green arrows) to cuproproteins (dark green circles), including metallothioneins Crs5 and Cup1, in for example Saccharomyces cerevisiae, by copper metallochaperones (pale green circles, or ovals if membrane associated) ENSG00000173992 ENSG00000138495 ENSG00000166260 ENSG00000133028 PMC6301151__F8 Schematic graphic of the mechanism underlying chondrogenesis driven by PC nanofiber membranes ENSG00000178860 ENSG00000139219 ENSG00000125398 ENSG00000157766 ENSG00000173599 ENSG00000056558 ENSG00000162692 PMC2377014__F10 BDNF enhancement of glutamate-induced phase shifting in the SCN, and potential locations in the signaling pathway where ethanol could inhibit this process ENSG00000291971 ENSG00000145321 ENSG00000166278 PMC9577160__F2 Promoter Methylation of Tumor Suppressors in Thyroid Carcinoma: A Systematic Review ENSG00000100234 ENSG00000090402 ENSG00000135446 ENSG00000020633 ENSG00000165409 PMC9146702__F1 An Insight into the Novel Immunotherapy and Targeted Therapeutic Strategies for Hepatocellular Carcinoma and Cholangiocarcinoma ENSG00000122025 ENSG00000105397 ENSG00000198793 PMC6883840__F10 Proteins and metabolites in JK1 that change by >2-fold relative to wild-type E ENSG00000197713 ENSG00000153574 PMC6947886__F3 Differentially expressed genes in the estrogen signaling pathway ENSG00000171791 ENSG00000127948 PMC3233269__F1 PA can be generated de novo,, by sequential enzyme-catalyzed acylations of glycerol-3-phosphate, or in response to cell signaling pathways () ENSG00000198793 ENSG00000173599 ENSG00000198670 PMC9414909__F4 Chemistry, Biosynthesis and Pharmacology of Viniferin: Potential Resveratrol-Derived Molecules for New Drug Discovery, Development and Therapy ENSG00000167419 PMC6757285__F1 Glutamine-dependent regulation of BMSC osteogenic and adipocyte differentiation ENSG00000198793 ENSG00000115419 PMC5386675__F3 Identification of evolutionarily conserved DNA damage response genes that alter sensitivity to cisplatin ENSG00000012061 ENSG00000104884 ENSG00000187790 ENSG00000033800 ENSG00000115904 ENSG00000105953 ENSG00000135587 ENSG00000183765 ENSG00000116001 ENSG00000090316 ENSG00000175054 ENSG00000134899 ENSG00000134574 ENSG00000174748 ENSG00000156958 ENSG00000070950 ENSG00000197299 ENSG00000077312 ENSG00000137074 ENSG00000134121 ENSG00000080603 ENSG00000066427 ENSG00000149554 ENSG00000136936 PMC4997401__F5 Promoter-specific DNA methylation of genes in the Kyoto Encyclopedia of Genes and Genomes (KEGG) mitogen-activated protein kinase (MAPK) signaling pathway ENSG00000087095 ENSG00000170458 ENSG00000130159 ENSG00000175104 ENSG00000081189 ENSG00000026103 PMC11648684__F8 M6A on apoptosis ENSG00000149658 ENSG00000156026 ENSG00000136997 ENSG00000073792 ENSG00000165819 PMC8989557__F2 Understanding of Immune Escape Mechanisms and Advances in Cancer Immunotherapy ENSG00000115415 ENSG00000163599 ENSG00000168610 PMC8989557__F1 Understanding of Immune Escape Mechanisms and Advances in Cancer Immunotherapy ENSG00000026103 PMC9239699__F3 ERH Interacts With EIF2A and Regulates the EIF2A/ATF4/CHOP Pathway in Bladder Cancer Cells ENSG00000166441 ENSG00000086589 ENSG00000162244 ENSG00000089157 ENSG00000084110 ENSG00000160679 ENSG00000278270 ENSG00000125691 ENSG00000280858 ENSG00000011304 ENSG00000071082 ENSG00000132341 ENSG00000280548 PMC8551388__F3 Hypoxia-Induced Neuroinflammation in Alzheimer’s Disease: Potential Neuroprotective Effects of Centella asiatica ENSG00000142192 ENSG00000125538 ENSG00000079999 PMC3233269__F9 G protein-coupled receptors (GPCR) trigger dissociation of GA and GBG heterotrimeric G proteins upon agonist stimulation ENSG00000291507 ENSG00000163914 ENSG00000173599 ENSG00000198670 PMC6446704__F2 Regulation of FABP4/aP2 secretion from adipocytes ENSG00000042832 PMC3227953__F1 PI3K/Akt/mTOR pathway signaling in tumor and vascular endothelial cells ENSG00000125879 ENSG00000134086 PMC5735818__F1 Schematic overview of the TEK signaling pathway which was built with CellDesigner 4.4 ENSG00000169291 ENSG00000136997 ENSG00000171540 PMC5133984__F6 Schematic diagram showing the signaling pathways leading to METH- and gp120-induced autophagy ENSG00000198793 ENSG00000057663 PMC8064670__F1 GM-CSF signaling pathways ENSG00000099985 ENSG00000137193 ENSG00000137265 PMC8338747__F1 ExTreg generation ENSG00000103266 ENSG00000159216 ENSG00000137033 ENSG00000198793 ENSG00000107485 ENSG00000049768 ENSG00000067955 ENSG00000168610 PMC7374866__F7 B.coccineus ethanol leaf extract induces cell cycle arrest and apoptosis via the p53 dependent pathway ENSG00000002330 ENSG00000135446 PMC3279755__F1 Signaling pathways of the fibroblast growth factor receptor in neural stem cells ENSG00000110395 PMC6296511__F3 Proteomic analysis of heart failure hospitalization among patients with chronic kidney disease: The Heart and Soul Study ENSG00000181104 ENSG00000203710 ENSG00000244731 ENSG00000120885 ENSG00000115718 ENSG00000122194 ENSG00000178726 ENSG00000182326 ENSG00000104368 ENSG00000236625 ENSG00000184500 ENSG00000180210 ENSG00000126218 ENSG00000173369 ENSG00000101981 ENSG00000117525 ENSG00000011422 ENSG00000164344 ENSG00000113889 ENSG00000039537 ENSG00000009724 ENSG00000003436 ENSG00000113600 ENSG00000291559 ENSG00000166278 ENSG00000176919 ENSG00000117322 ENSG00000173372 ENSG00000117601 ENSG00000057593 ENSG00000175899 ENSG00000080618 ENSG00000198734 ENSG00000100739 ENSG00000276838 PMC3148577__F1 Metabolic networks of Corynebacterim glutamicum (a) and Brassica napus (b) corresponding to the experimental fluxes measured by and respectively ENSG00000122966 ENSG00000186063 ENSG00000172005 PMC3148577__F3 A heterotrophic plant cells ENSG00000122966 ENSG00000172005 PMC6885181__F5 HIF-1-miR-219-SMC4 axis regulates proliferation and migration of HCC under hypoxic condition ENSG00000135446 ENSG00000123374 PMC11678862__F2 Dietary restriction on lipid profile changes and healthspan ENSG00000150907 PMC11049451__F3 Estrogen biosynthesis pathway from cholesterol to estetrol with the enzymes involved ENSG00000203859 PMC11678862__F1 Molecular mechanisms linking dietary restriction to lipid metabolism and health benefits ENSG00000167910 PMC5314358__F8 Suppression of TAK1 pathway by shear stress counteracts the inflammatory endothelial cell phenotype induced by oxidative stress and TGFB1 ENSG00000137834 ENSG00000108691 ENSG00000127528 ENSG00000169429 ENSG00000007908 ENSG00000162692 ENSG00000175104 ENSG00000136826 PMC10385841__F6 Top networks associated with lipid metabolism identified in PIEs infected with G5P ENSG00000064309 ENSG00000260314 ENSG00000189184 ENSG00000185070 ENSG00000048052 ENSG00000142347 ENSG00000169851 ENSG00000158258 ENSG00000109705 PMC8551388__F1 Hypoxia-Induced Neuroinflammation in Alzheimer’s Disease: Potential Neuroprotective Effects of Centella asiatica ENSG00000142192 ENSG00000125538 ENSG00000079999 PMC10385841__F5 Top networks associated with lipid metabolism identified in PIEs infected with G9P[13] ENSG00000145247 ENSG00000168955 ENSG00000261832 ENSG00000103089 ENSG00000162630 ENSG00000148926 ENSG00000146205 ENSG00000147256 ENSG00000138744 ENSG00000117036 ENSG00000285199 ENSG00000171224 ENSG00000140022 ENSG00000100647 ENSG00000109881 PMC10385841__F4 Rotavirus interactions with the host innate immune system ENSG00000151882 ENSG00000213928 ENSG00000088888 ENSG00000131142 ENSG00000184995 ENSG00000089127 ENSG00000115415 ENSG00000157601 ENSG00000142166 PMC5569936__F7 Metabolic control involved in aging and on the cardiovascular system ENSG00000163235 ENSG00000198793 PMC11535070__F4 Proposed crosstalk model between TET1, WNT, mir200b, and miR494 in CRC progression ENSG00000168283 ENSG00000169554 ENSG00000134982 ENSG00000168036 PMC8996963__F2 Thromboinflammatory Processes at the Nexus of Metabolic Dysfunction and Prostate Cancer: The Emerging Role of Periprostatic Adipose Tissue ENSG00000087245 ENSG00000135218 ENSG00000110799 ENSG00000157227 ENSG00000026103 PMC11857948__F9 Selected differentially significant signaling pathways in M ENSG00000081041 ENSG00000119535 ENSG00000163739 ENSG00000198793 ENSG00000137193 ENSG00000168610 ENSG00000145623 ENSG00000149968 ENSG00000169429 ENSG00000136869 ENSG00000172936 ENSG00000100985 ENSG00000056736 ENSG00000115009 ENSG00000168685 PMC6236061__F1 PPAR signaling pathway ENSG00000161533 PMC9445132__F3 Mitophagy: A potential therapeutic target for insulin resistance ENSG00000177169 ENSG00000291971 ENSG00000284099 ENSG00000158828 ENSG00000069509 PMC2655678__F1 ATM activation in response to DNA DSBs ENSG00000149311 ENSG00000012048 ENSG00000144554 ENSG00000123374 PMC9126300__F2 Deciphering the Link Between ERUPR Signaling and MicroRNA in Pathogenesis of Alzheimer’s Disease ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC5627649__F5 Signaling and gene regulatory networks in mammalian lens development ENSG00000150938 ENSG00000186575 ENSG00000281324 ENSG00000162337 ENSG00000170558 PMC9126300__F1 Deciphering the Link Between ERUPR Signaling and MicroRNA in Pathogenesis of Alzheimer’s Disease ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC5627649__F4 Signaling and gene regulatory networks in mammalian lens development ENSG00000102878 ENSG00000117707 ENSG00000100122 ENSG00000160202 PMC3959225__F5 Pharmacogenomics of insulin-like growth factor-I generation during GH treatment in children with GH deficiency or Turner syndrome ENSG00000142192 ENSG00000002330 PMC11791135__F6 Exploration of the mechanism of Lithospermum erythrorhizon oil in treating atopic dermatitis based on network pharmacology and experimental validation of the PI3K-Akt pathway regulation ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000002330 ENSG00000105401 ENSG00000186716 ENSG00000115718 PMC5752874__F3 HMGB1 receptor and possible signaling pathways ENSG00000070831 ENSG00000155926 ENSG00000189403 PMC8478908__F2 TNFA/TNFR1 signaling activates necroptosis and triggers apoptosis and inflammation ENSG00000137275 ENSG00000102871 ENSG00000157625 ENSG00000136869 ENSG00000166278 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 ENSG00000026103 PMC6957738__F1 ERBB and signaling effectors in PKD ENSG00000047410 ENSG00000167580 ENSG00000163235 ENSG00000291971 ENSG00000113070 ENSG00000138798 ENSG00000001626 PMC7202494__F7 Let-7f-5p/TARBP2 regulatory feedback loop in OS cells, which is induced by hypoxia and reduces the expression of let-7f-5p and TARBP2 in OS cells ENSG00000139546 ENSG00000168036 PMC6751321__F9 Diagram of the signaling mechanism involved in the myocardial protection mediated by carvacrol ENSG00000104321 PMC8834070__F2 Shifting the Focus of Signaling Abnormalities in Colon Cancer ENSG00000138798 ENSG00000146648 PMC5936719__F1 Summary of unfolded protein response ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8834070__F4 Shifting the Focus of Signaling Abnormalities in Colon Cancer ENSG00000135446 ENSG00000177606 ENSG00000136997 ENSG00000168036 ENSG00000123374 ENSG00000105810 ENSG00000196628 PMC4872452__F2 Network analysis of blood transcripts ENSG00000291873 ENSG00000139572 ENSG00000065357 ENSG00000111726 ENSG00000159461 ENSG00000147885 ENSG00000140743 ENSG00000133115 PMC2673242__F1 Loss of PTEN function results in accumulation of PIP3, which activates a cascade of signaling molecules ENSG00000002330 ENSG00000198793 ENSG00000105656 PMC4381588__F1 Targeting ornithine decarboxylase reverses the LIN28/Let-7 axis and inhibits glycolytic metabolism in neuroblastoma ENSG00000288145 ENSG00000187772 PMC2268054__F2 Mutations in the glycoprotein 130 (gp130) receptor lead to an imbalance in downstream signalling pathways ENSG00000115415 ENSG00000168610 PMC8026307__F2 FOXO1 activity by periodontal microbiota in gingival epithelial cells ENSG00000087095 ENSG00000169554 ENSG00000102871 ENSG00000150907 PMC2268054__F1 Role of glycoprotein 130 (gp130) downstream signalling in the heart ENSG00000099985 ENSG00000115415 ENSG00000128342 ENSG00000168610 PMC5655319__F1 Update on the therapeutic significance of estrogen receptor beta in malignant gliomas ENSG00000198793 ENSG00000185591 ENSG00000132693 PMC2915629__F4 Identification of RON-targeting genes ENSG00000100811 ENSG00000005073 ENSG00000112964 ENSG00000122257 ENSG00000162772 ENSG00000071564 ENSG00000150991 ENSG00000143514 ENSG00000172534 ENSG00000060656 ENSG00000067606 ENSG00000103546 ENSG00000177606 ENSG00000139687 PMC9107227__F7 Positive feedback loop between gastric cancer cells and tumor-associated macrophage induces malignancy progression ENSG00000163464 ENSG00000115415 ENSG00000109320 ENSG00000169429 PMC6685392__F4 Multi-loop model of AD: an integrated perspective on the Wnt/GSK3B, Alpha-synuclein, and type 3 diabetes hypotheses ENSG00000119912 PMC10216514__F5 Ferroptosis signaling pathway ENSG00000167468 ENSG00000115419 PMC1766919__F1 Signalling footprints of the TNF/TNF-R superfamily ENSG00000102871 ENSG00000082512 ENSG00000168040 ENSG00000127191 PMC6685392__F1 Dysfunctions in canonical Wnt-Signaling contribute to the neuropathology of Alzheimer disease (AD) ENSG00000142192 ENSG00000281324 ENSG00000168036 PMC3977149__F1 p53 effects multiple areas of cellular metabolism ENSG00000135423 ENSG00000078237 ENSG00000284194 PMC11607912__F3 Differentially expressed genes and DNA (hydroxy)methylation levels within the TRP metabolic pathway and NAD pathway ENSG00000143799 ENSG00000125166 ENSG00000172890 ENSG00000162882 ENSG00000130649 ENSG00000278488 ENSG00000205309 ENSG00000103257 ENSG00000137944 ENSG00000181192 ENSG00000188676 ENSG00000102699 ENSG00000116133 ENSG00000291814 ENSG00000180432 ENSG00000157064 ENSG00000008130 ENSG00000096717 ENSG00000091140 PMC11607912__F6 Gene regulatory network (GRN) of TRP and NAD pathway ENSG00000143799 ENSG00000187531 ENSG00000105835 ENSG00000128918 ENSG00000140505 ENSG00000130649 ENSG00000105953 ENSG00000077463 ENSG00000120437 ENSG00000103257 ENSG00000142082 ENSG00000105607 ENSG00000140465 ENSG00000124212 ENSG00000073756 ENSG00000134716 ENSG00000188676 ENSG00000283100 ENSG00000168003 ENSG00000096717 ENSG00000075239 ENSG00000113790 ENSG00000091140 PMC7999074__F2 Activity of YAP/TAZ is influenced by various metabolic cues ENSG00000147162 ENSG00000067057 ENSG00000198793 ENSG00000163914 ENSG00000113161 ENSG00000114268 ENSG00000168036 ENSG00000135069 ENSG00000111371 ENSG00000103257 ENSG00000159399 ENSG00000026103 PMC7999074__F1 Hippo signaling pathway comprises a cascade of phosphorylation and activation of kinases, which ultimately regulate YAP and TAZ subcellular localization ENSG00000186575 ENSG00000144560 ENSG00000131023 PMC8222692__F3 Treg: A Promising Immunotherapeutic Target in Oral Diseases ENSG00000102962 ENSG00000137033 ENSG00000134982 ENSG00000198793 ENSG00000049768 PMC11891403__F6 Exogenous fatty acids inhibit fatty acid synthesis by competing with endogenously generated substrates for phospholipid synthesis in Escherichia coli ENSG00000198670 ENSG00000168040 PMC8704804__F1 Association of Genes of the NO Pathway with Altitude Disease and Hypoxic Pulmonary Hypertension ENSG00000081181 ENSG00000113492 ENSG00000118520 PMC4468904__F6 Pharmacogenomic and clinical data link non-pharmacokinetic metabolic dysregulation to drug side effect pathogenesis ENSG00000262635 ENSG00000131480 ENSG00000241644 PMC5904768__F3 DNA damage stress response in the TRIM59 network ENSG00000149311 ENSG00000175054 ENSG00000064393 ENSG00000087586 ENSG00000177519 ENSG00000153827 ENSG00000183765 ENSG00000198625 PMC5904768__F5 p53 signaling in the TRIM59 network ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000064393 ENSG00000123374 ENSG00000118971 ENSG00000183765 PMC8129027__F1 Study of the Regulatory Mechanism of the CB1/PPARG2/PLIN1/HSL Pathway for Fat Metabolism in Cattle ENSG00000150907 ENSG00000169047 ENSG00000197142 ENSG00000164398 ENSG00000096717 ENSG00000123983 ENSG00000132170 PMC11768235__F1 Exosome-mediated communication between immune cells and keratinocytes contributes to the development of psoriasis ENSG00000102837 ENSG00000162892 ENSG00000136688 PMC6280699__F8 Proinflammatory and anti-inflammatory effects of IFNB in CF: (A) IFNB triggers JAK/STATsignaling pathway activation (STAT1, STAT3, and STAT3 proteins) ENSG00000115415 ENSG00000168610 PMC8509311__F1 Impact of Selenium Deficiency on Cardiovascular Function ENSG00000113811 ENSG00000250722 ENSG00000178980 ENSG00000291928 ENSG00000179918 ENSG00000198843 PMC7238364__F5 PPI network analysis of the overlapping DEGs ENSG00000104856 ENSG00000180190 ENSG00000166439 ENSG00000100906 ENSG00000036672 ENSG00000157193 ENSG00000101057 ENSG00000121073 ENSG00000091651 ENSG00000231377 ENSG00000153015 ENSG00000167881 ENSG00000069869 ENSG00000109466 ENSG00000175166 ENSG00000136504 ENSG00000127824 ENSG00000108671 PMC8909279__F2 Nutrients against Glucocorticoid-Induced Muscle Atrophy ENSG00000198793 ENSG00000139112 PMC7795823__F6 Proposed mechanisms for the action of ACF on melanoma cells under normoxic conditions ENSG00000140992 ENSG00000128272 PMC10149906__F1 Building on the backbone of CD47-based therapy in cancer: Combination strategies, mechanisms, and future perspectives ENSG00000164430 ENSG00000198053 PMC11018997__F6 Multiple functions of the nonstructural protein 3D in picornavirus infection ENSG00000213928 ENSG00000088888 ENSG00000167207 ENSG00000105397 ENSG00000276561 PMC11046940__F3 Regulation of autophagy to affect radiosensitivity involves a complex network of signaling pathway ENSG00000149311 ENSG00000177169 ENSG00000291971 ENSG00000198793 ENSG00000189403 ENSG00000168610 PMC6122069__F1 Two major signaling axes in IGF-1-mediated EMTs in human breast, lung, and gastric cancers ENSG00000182718 ENSG00000169903 ENSG00000169554 ENSG00000122691 ENSG00000291971 ENSG00000185201 ENSG00000169047 ENSG00000168036 ENSG00000168610 ENSG00000140443 PMC11046940__F2 Mechanisms by which autophagy modulation affects chemosensitivity are multifaceted and involve multiple signaling pathways ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000083290 ENSG00000144848 ENSG00000284099 ENSG00000167965 ENSG00000145782 ENSG00000057663 PMC2852400__F7 Inhibition of the Proprotein Convertases Represses the Invasiveness of Human Primary Melanoma Cells with Altered p53, CDKN2A and N-Ras Genes ENSG00000157764 ENSG00000135446 PMC8306625__F1 PRR-Mediated Signaling Pathways in the Regulation of Oxidative Stress and Inflammatory Diseases ENSG00000140279 ENSG00000086991 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000188747 PMC8527034__F7 Astragalus Polysaccharide Reduces Blood Pressure, Renal Damage, and Dysfunction Through the TGFB1-ILK Pathway PMC8306625__F3 PRR-Mediated Signaling Pathways in the Regulation of Oxidative Stress and Inflammatory Diseases ENSG00000273992 ENSG00000162711 ENSG00000088888 ENSG00000265972 PMC8142022__F4 Metabolism and cell signaling in ferroptosis ENSG00000163930 ENSG00000186575 PMC3989988__F1 De novo serine biosynthesis diverges from glycolysis ENSG00000135423 ENSG00000092621 ENSG00000078237 ENSG00000146733 ENSG00000131143 PMC8223745__F1 Current Challenges and Future Perspectives of Renal Tubular Dysfunction in Diabetic Kidney Disease ENSG00000115415 ENSG00000118515 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000168610 ENSG00000184216 ENSG00000171109 PMC11796622__F5 IL17RA mutation and downstream signaling pathway ENSG00000175104 ENSG00000163702 PMC7892335__F1 Loss and revival of androgen receptor signaling in advanced prostate cancer ENSG00000176692 ENSG00000183876 ENSG00000087586 ENSG00000139687 PMC5697417__F2 IFITM proteins are involved in various cellular processes with direct and indirect impacts on immunity ENSG00000110497 ENSG00000197296 ENSG00000291971 ENSG00000198793 ENSG00000151929 PMC5731828__F1 An emerging role for the ribosome as a nexus for post-translational modifications ENSG00000291931 ENSG00000142541 ENSG00000008988 ENSG00000070814 ENSG00000124614 ENSG00000115268 ENSG00000149273 PMC7281607__F1 Simpified major metabolic pathways of tryptophan (TRP) in humans PMC4445995__F2 Stem cell response to matrix stiffness by integin, cytoskeleton and signal transduction crosstalk ENSG00000285109 ENSG00000179348 PMC98951__F2 Signaling pathways of IFNA, IFNB, and cytoplasmic dsRNA ENSG00000105397 ENSG00000115415 PMC4082998__F1 Regulatory mechanisms for glycogenolysis and K+ uptake in brain astrocytes ENSG00000291971 ENSG00000146648 ENSG00000221946 PMC11907956__F5 PTMs of CD47: When CD47 on the surface of tumor cells interacts with SIRPA on macrophages, it causes the intracellular portion of SIRPA to be phosphorylated ENSG00000132109 ENSG00000198053 PMC12021826__F10 Schematic diagram illustrating how AREG triggers macrophage pyroptosis through the EGFR/TLR4 signaling pathway during inflammatory responses ENSG00000278718 ENSG00000109321 ENSG00000137818 ENSG00000172936 ENSG00000136869 ENSG00000146648 PMC11907956__F4 Structure and PTMs of PD-L1 (phosphorylation, glycosylation and ubiquitination): Presented here is a schematic diagram that illustrates the functional domains of PD-L1 as well as its diverse PTMs ENSG00000132109 ENSG00000124422 ENSG00000091317 ENSG00000138798 ENSG00000121067 ENSG00000179913 ENSG00000101695 ENSG00000166233 ENSG00000069869 ENSG00000117650 ENSG00000135446 ENSG00000143258 ENSG00000105723 ENSG00000151948 PMC4638047__F7 Pathway analysis highlights APP is a central hub interacting with nearly 40% of candidate molecules in EGS ENSG00000117691 ENSG00000143420 ENSG00000197971 ENSG00000188157 ENSG00000136854 ENSG00000132639 ENSG00000197702 PMC6549079__F5 Signaling pathways related to RUNX3 ENSG00000020633 ENSG00000168036 ENSG00000196628 PMC6549079__F4 Signaling pathways related to RUNX2 ENSG00000152266 ENSG00000169554 ENSG00000138798 ENSG00000168036 ENSG00000146648 PMC11537862__F3 Possible pathways of apoptosis inhibition by Brucella ENSG00000069869 ENSG00000117118 PMC6549079__F3 Signaling pathways related to RUNX1 ENSG00000159216 ENSG00000138798 ENSG00000168036 ENSG00000146648 PMC11537862__F2 Brucella triggers inflammatory responses ENSG00000162711 ENSG00000167207 ENSG00000163568 ENSG00000172936 ENSG00000265972 ENSG00000127191 PMC11876635__F7 SEMA3F-dependent pathways ENSG00000198793 ENSG00000118257 PMC11907956__F8 PTMs of TIGIT: TIGIT binds to CD112, CD113, and CD155 ENSG00000181847 ENSG00000134982 ENSG00000175104 PMC4705549__F5 Multiple functional linear model for association analysis of RNA-seq with imaging ENSG00000126231 ENSG00000243147 ENSG00000134825 ENSG00000177352 PMC6371002__F2 Mechanistic cross-connection between the transforming growth factor beta pathway and bone morphogenetic protein signaling ENSG00000010704 ENSG00000106327 ENSG00000105697 ENSG00000204217 PMC6274916__F2 Complement activation by foreign biomaterial surfaces in bone tissue, and strategies to modulate the complement system ENSG00000178860 ENSG00000203710 PMC2819049__F3 Different components of shelterin are dedicated to different aspects of the end-protection problem ENSG00000149311 ENSG00000175054 ENSG00000128513 PMC1389768__F1 The Challenge of Characterizing Operations in the Mechanisms Underlying Behavior ENSG00000039537 ENSG00000166278 PMC10376170__F2 Targeting Triple-Negative Breast Cancer by the Phytopolyphenol Carnosol: ROS-Dependent Mechanisms ENSG00000128272 ENSG00000198793 ENSG00000168610 PMC6512804__F6 Fatty livers demonstrate a premalignant signature ENSG00000132906 ENSG00000134086 ENSG00000134982 ENSG00000163914 ENSG00000164690 ENSG00000128602 ENSG00000164305 PMC7870817__F5 GSK3Beta-Beta-catenin-TCF1 pathway improves naive T cell activation in old adults by upregulating miR-181a ENSG00000100811 ENSG00000168036 PMC8105434__F8 Trueperella pyogenes pyolysin inhibits lipopolysaccharide-induced inflammatory response in endometrium stromal cells via autophagy- and ATF6-dependent mechanism ENSG00000162711 ENSG00000125538 PMC8584071__F3 Epithelial to Mesenchymal Transition: A Challenging Playground for Translational Research. Current Models and Focus on TWIST1 Relevance and Gastrointestinal Cancers ENSG00000122691 ENSG00000168036 ENSG00000168610 PMC8215263__F1 Effect of Oxidative Stress on Diaphragm Dysfunction and Exercise Intervention in Chronic Obstructive Pulmonary Disease ENSG00000175567 PMC11966298__F4 Applications of metal-based nanomaterials in tumor immunotherapy ENSG00000183735 ENSG00000164430 PMC11966298__F1 CGAS-STING pathway ENSG00000169245 ENSG00000164430 ENSG00000138755 PMC9403721__F1 Inhibiting Cytoprotective Autophagy in Cancer Therapy: An Update on Pharmacological Small-Molecule Compounds ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000198382 ENSG00000083290 ENSG00000144848 ENSG00000145782 PMC2753670__F3 Integration of ITAM and cytokine Jak–STAT signaling ENSG00000105397 ENSG00000115415 PMC6016592__F2 The two faces of pannexins: new roles in inflammation and repair ENSG00000278718 ENSG00000150782 ENSG00000125538 ENSG00000110218 PMC6763828__F9 Schematic model of intracellular signal components that control S-phase entry in vestibular epithelia from neonatal mammals ENSG00000124102 PMC2799977__F2 TLR signaling upon intrinsic cellular defenses ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000125538 ENSG00000134070 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000182606 ENSG00000164342 PMC5690809__F7 Histone acetyltransferase KAT6A upregulates PI3K/AKT signaling through TRIM24 binding ENSG00000083168 ENSG00000156983 ENSG00000122779 ENSG00000121879 PMC4172307__F1 Regulation of Tumor Angiogenesis and Choroidal Neovascularization by Endogenous Angioinhibitors ENSG00000198793 ENSG00000213614 ENSG00000173039 ENSG00000026103 PMC5890159__F1 Nutrient activation of PKA in the yeast ENSG00000159224 ENSG00000116741 ENSG00000174840 PMC10487526__F9 Proinflammatory immune response in BV-2 microglial cells induced by NfEVs ENSG00000168610 PMC9492833__F2 Vesicle trafficking and vesicle fusion: mechanisms, biological functions, and their implications for potential disease therapy ENSG00000126775 ENSG00000135823 ENSG00000225190 ENSG00000168818 ENSG00000113734 ENSG00000118640 ENSG00000136874 ENSG00000143858 ENSG00000292366 ENSG00000053501 ENSG00000102189 ENSG00000265808 ENSG00000170310 ENSG00000220205 ENSG00000079950 ENSG00000139719 PMC5289991__F2 MYC-driven self-reinforcing loop in ESCs ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000136997 ENSG00000139154 ENSG00000128342 ENSG00000158050 ENSG00000164086 PMC7283439__F7 FG-4592 activity on depression PMC5289991__F1 MYC regulatory networks in pluripotent stem cells ENSG00000136997 ENSG00000132600 ENSG00000139154 ENSG00000128342 ENSG00000104332 ENSG00000168610 ENSG00000158050 ENSG00000164086 PMC3798916__F1 Methylation cycle ENSG00000133027 PMC9403519__F9 Posaconazole inhibits the stemness of cancer stem-like cells by inducing autophagy and suppressing the Wnt/Beta-catenin/survivin signaling pathway in glioblastoma ENSG00000026508 ENSG00000168036 ENSG00000057663 PMC3185579__F3 TLR-dependent and independent IFN-I induction, signaling and action ENSG00000183735 ENSG00000213928 ENSG00000239732 ENSG00000187608 ENSG00000105397 ENSG00000115415 ENSG00000157601 ENSG00000172936 ENSG00000135828 ENSG00000276561 ENSG00000164342 ENSG00000172183 PMC7394593__F1 The roles played by the TCA cycle and the Warburg effect in gastrointestinal cancers and normal tissues ENSG00000067057 ENSG00000114268 ENSG00000105953 ENSG00000107874 ENSG00000164104 ENSG00000166164 PMC9646879__F7 Various biological functions of the human Rix1 scaffolding complex ENSG00000161956 ENSG00000136891 ENSG00000141456 PMC6532258__F7 Proposed model for GPAA1 promoting growth and metastasis of gastric cancer ENSG00000197858 ENSG00000146648 PMC8430477__F6 New Insight into the Effects of Metformin on Diabetic Retinopathy, Aging and Cancer: Nonapoptotic Cell Death, Immunosuppression, and Effects beyond the AMPK Pathway ENSG00000107562 ENSG00000170558 ENSG00000198793 ENSG00000171823 ENSG00000121966 PMC8430477__F5 New Insight into the Effects of Metformin on Diabetic Retinopathy, Aging and Cancer: Nonapoptotic Cell Death, Immunosuppression, and Effects beyond the AMPK Pathway ENSG00000168003 ENSG00000151012 ENSG00000167468 PMC3213329__F3 Ingenuity pathway analysis of phosphatidylinositol 3-kinase (PI3K) signaling pathway affected by angiotensin II ENSG00000002330 ENSG00000198793 ENSG00000168036 PMC8430477__F7 New Insight into the Effects of Metformin on Diabetic Retinopathy, Aging and Cancer: Nonapoptotic Cell Death, Immunosuppression, and Effects beyond the AMPK Pathway ENSG00000163739 ENSG00000276644 ENSG00000049768 ENSG00000188389 PMC8430477__F2 New Insight into the Effects of Metformin on Diabetic Retinopathy, Aging and Cancer: Nonapoptotic Cell Death, Immunosuppression, and Effects beyond the AMPK Pathway ENSG00000128272 ENSG00000112715 ENSG00000162692 ENSG00000096717 ENSG00000079999 PMC8430477__F1 New Insight into the Effects of Metformin on Diabetic Retinopathy, Aging and Cancer: Nonapoptotic Cell Death, Immunosuppression, and Effects beyond the AMPK Pathway ENSG00000177169 ENSG00000198793 ENSG00000142082 ENSG00000116157 PMC5358377__F6 Cellular localization of the autophagy genes regulated by 1,25(OH)2D3 (Ingenuity Pathway Analysis software) in MCF-7 cells ENSG00000152348 ENSG00000163625 ENSG00000198793 ENSG00000144848 ENSG00000171791 ENSG00000136874 PMC4228291__F1 Wnt signaling pathway and its key components ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8430477__F4 New Insight into the Effects of Metformin on Diabetic Retinopathy, Aging and Cancer: Nonapoptotic Cell Death, Immunosuppression, and Effects beyond the AMPK Pathway ENSG00000096717 ENSG00000141456 PMC8233448__F1 NLRP3 inflammasome and COVID-19: Activation, pathogenesis and therapeutic strategies ENSG00000162711 ENSG00000125538 PMC8430477__F3 New Insight into the Effects of Metformin on Diabetic Retinopathy, Aging and Cancer: Nonapoptotic Cell Death, Immunosuppression, and Effects beyond the AMPK Pathway ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC12241215__F3 Diagram represents various therapeutic strategies targeting AML through different molecular mechanisms ENSG00000128602 ENSG00000026103 PMC8523334__F3 TNFR2+ Tregs in COVID-19: An overview and a potential therapeutic strategy ENSG00000056558 ENSG00000131323 ENSG00000127191 PMC9458863__F3 Current progress of ferroptosis study in ovarian cancer ENSG00000145604 ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000198793 ENSG00000146648 ENSG00000155760 PMC1351175__F11 Proposed Receptor Ck – dependent signaling pathway involved in hTERT gene regulation at the transcriptional level ENSG00000130164 ENSG00000173599 ENSG00000185591 PMC11519599__F3 Signal transduction pathways in ferroptosis under HS ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000197905 ENSG00000136869 PMC7182338__F4 BCR signaling pathway and its targeted inhibition ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000197943 ENSG00000277943 ENSG00000010671 PMC4137125__F3 Schematic representation depicting deleterious effects of overnutrition and obesity in the vasculature and targets for DPP-4i ENSG00000105329 ENSG00000197635 ENSG00000169047 ENSG00000084774 PMC11519599__F2 Signal transduction pathways of necroptosis under HS ENSG00000124256 ENSG00000284774 ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 ENSG00000164342 PMC3070844__F3 Top-scoring network created by Ingenuity Pathway Analysis ENSG00000182718 ENSG00000181163 ENSG00000197632 ENSG00000105568 PMC8103163__F7 Emodin Alleviates Severe Acute Pancreatitis-Associated Acute Lung Injury by Inhibiting the Cold-Inducible RNA-Binding Protein (CIRP)-Mediated Activation of the NLRP3/IL-1B/CXCL1 Signaling ENSG00000278718 ENSG00000162711 ENSG00000125538 ENSG00000136869 PMC8290830__F4 Autophagy in hepatic fibrosis ENSG00000177169 ENSG00000198793 ENSG00000145782 ENSG00000057663 PMC11934544__F7 Protective mechanism of EA on IVDD PMC8290830__F2 Autophagy in hepatic fibrosis ENSG00000101901 ENSG00000177169 ENSG00000198793 ENSG00000189403 ENSG00000145782 ENSG00000057663 ENSG00000198925 PMC9471313__F3 Excessive intake of sugar: An accomplice of inflammation ENSG00000148346 ENSG00000125538 ENSG00000136869 PMC7586926__F1 SARS-CoV-2 pathogenesis ENSG00000130234 ENSG00000184012 PMC3323898__F5 Graphical representation of the known connections between the Wnt/Beta-catenin pathway and the Notch1 signaling pathways, according to the knowledge of the current literature ENSG00000135547 ENSG00000138795 ENSG00000137673 ENSG00000134982 ENSG00000148400 ENSG00000168036 ENSG00000276920 ENSG00000189283 ENSG00000069869 ENSG00000198435 ENSG00000157227 ENSG00000136997 ENSG00000118515 ENSG00000133961 PMC4365881__F4 Extracellular regulation of satellite cell fate ENSG00000009709 ENSG00000162512 ENSG00000168036 PMC9139349__F2 Alterations of Mitochondrial Network by Cigarette Smoking and E-Cigarette Vaping ENSG00000116688 ENSG00000171109 ENSG00000106459 ENSG00000214253 PMC5290970__F8 Signaling switch between hyperglycemia and normoglycemia ENSG00000124102 ENSG00000169047 PMC6656753__F5 Significant dysregulation of P53 pathway in urothelial cells exposed to either S ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000136997 ENSG00000123374 ENSG00000196470 ENSG00000164305 ENSG00000140464 ENSG00000026103 PMC6656753__F4 Significant dysregulation of genes involved in Colorectal Cancer Signaling Pathway in urothelial cells ENSG00000132906 ENSG00000002330 ENSG00000134982 ENSG00000113318 ENSG00000138798 ENSG00000163914 ENSG00000095002 ENSG00000164305 PMC7520849__F1 RAD51 function during HR and replication fork reversal and protection ENSG00000165556 ENSG00000012048 ENSG00000083093 ENSG00000138346 ENSG00000178295 ENSG00000188827 ENSG00000051180 ENSG00000139618 PMC7020766__F3 Pathway of diabetic cardiomyopathy network (Blue circle stands for breast cancer gene ENSG00000135218 ENSG00000137673 ENSG00000288174 ENSG00000198793 ENSG00000134308 ENSG00000113161 ENSG00000108342 ENSG00000116717 ENSG00000106100 ENSG00000134716 ENSG00000167772 ENSG00000108691 ENSG00000148660 ENSG00000118785 ENSG00000066044 ENSG00000150907 ENSG00000125538 ENSG00000166501 ENSG00000136869 ENSG00000151617 ENSG00000096717 ENSG00000145349 ENSG00000140443 PMC6679874__F4 Regulation of genes and myomiRs expression in the IGF/PI3K/Akt signaling pathway during myogenesis ENSG00000009709 ENSG00000111049 ENSG00000125414 ENSG00000122180 ENSG00000198793 ENSG00000081189 PMC5161695__F7 Glucose metabolism reprogrammed by overexpression of IKK-epsilon promotes pancreatic tumor growth ENSG00000262785 ENSG00000124253 ENSG00000159399 PMC4395454__F1 MLK3 Phophorylates AMPK Independently of LKB1 ENSG00000070831 ENSG00000065559 ENSG00000169032 ENSG00000171533 PMC7273095__F1 Androgen sensitivity gateway to COVID‐19 disease severity ENSG00000130234 ENSG00000184012 PMC3800061__F2 Basic NOD2/RIP2 pathway of NFKB activation ENSG00000167207 ENSG00000082512 ENSG00000157625 ENSG00000175104 ENSG00000127191 PMC12236749__F3 BMSC-Exos alleviate MIRI ENSG00000163930 ENSG00000187531 ENSG00000151012 ENSG00000116688 ENSG00000150907 ENSG00000175899 ENSG00000136869 ENSG00000168610 PMC3251532__F5 The lymphocte-specific gene (A) or urine peptide (B) markers ENSG00000104320 ENSG00000163794 ENSG00000213402 ENSG00000103222 ENSG00000004961 ENSG00000118971 PMC12236749__F2 BMSC-Exos ameliorate MI ENSG00000169967 ENSG00000162711 ENSG00000145536 ENSG00000078747 ENSG00000136869 ENSG00000154188 PMC2718437__F4A Gene Expression Changes during the Development of Acute Lung Injury Role of Transforming Growth Factor B ENSG00000011422 ENSG00000197632 ENSG00000122194 ENSG00000276838 ENSG00000104368 PMC12236749__F5 BMSC-Exos ameliorate other CVDs ENSG00000162711 ENSG00000150907 ENSG00000112562 ENSG00000168036 ENSG00000189403 ENSG00000136869 ENSG00000136826 PMC6683488__F1 Molecular landscape of SCLC ENSG00000149311 ENSG00000175054 ENSG00000172716 ENSG00000115415 ENSG00000136997 ENSG00000087586 ENSG00000125347 ENSG00000168610 ENSG00000139687 ENSG00000139352 PMC11667561__F7 Illustrates the TCA cycle, MVA Pathway and downstream of saponins synthesis metabolic pathway ENSG00000180210 ENSG00000197429 ENSG00000139687 PMC12236749__F4 BMSC-Exos improve AS ENSG00000278718 ENSG00000162711 ENSG00000172216 ENSG00000079999 PMC539208__F2 MAPK pathway ENSG00000157764 ENSG00000177606 ENSG00000136997 ENSG00000203710 ENSG00000117322 PMC9604498__F10 Model integrating the network involving Churc1, Nodal and Notch-dependent pathways in the induction and segregation of germ layers in the Xenopus MZ ENSG00000188290 ENSG00000169554 ENSG00000148400 ENSG00000164458 ENSG00000156574 ENSG00000258289 PMC3956974__F3 Signaling control of CAR activation ENSG00000138798 ENSG00000096088 ENSG00000155974 ENSG00000146648 PMC12236749__F6 Cardiovascular-derived exosomes regulate the bone ENSG00000155011 ENSG00000104290 ENSG00000168036 PMC11395599__F4 Illustration of NETs, ROS, cancer mitochondrial oxidative damage and altered glucose metabolism, including the Warburg effect and glucose metabolic reprogramming, in human cancers is shown ENSG00000065911 ENSG00000100714 ENSG00000092621 ENSG00000135069 ENSG00000146733 ENSG00000115419 PMC9456504__F1 Antimicrobial Peptides in Gynecological Cancers ENSG00000111012 ENSG00000170558 ENSG00000124107 PMC4248747__F8 Proposed model for the control of Beta-catenin stability by RNF220/USP7 ENSG00000134982 ENSG00000187147 ENSG00000168036 PMC3483307__F5 Novel Genes and Pathways Modulated by Syndecan-1: Implications for the Proliferation and Cell-Cycle Regulation of Malignant Mesothelioma Cells ENSG00000104856 ENSG00000100906 ENSG00000153936 ENSG00000163235 ENSG00000130522 ENSG00000138798 ENSG00000136997 ENSG00000123374 ENSG00000137573 ENSG00000146648 PMC7338561__F2 Depiction of the modulation of NFKB signaling pathway by gastric microbiota, especially H ENSG00000168036 ENSG00000172936 ENSG00000106100 PMC8698353__F5 Effect Mechanism of Electroacupuncture at ST36 on the Injured Extensor Digitorum Longus in the Jumping Rat Model Based on mRNA-Seq Analysis ENSG00000142192 ENSG00000114737 ENSG00000136997 ENSG00000171791 ENSG00000164305 PMC4594238__F8 Sensory initiation of a co‐ordinated motor response: synaptic excitation underlying simple decision‐making ENSG00000042832 ENSG00000198125 PMC9532118__F1 E3 Ubiquitin Ligases: Potential Therapeutic Targets for Skeletal Pathology and Degeneration ENSG00000170365 ENSG00000137834 ENSG00000198742 PMC9641500__F2 Lysophospholipid Mediators in Health and Disease ENSG00000205639 ENSG00000063176 ENSG00000173599 ENSG00000198670 ENSG00000183018 PMC6745708__F1 The RTK signaling network and nodes of therapeutic blockade ENSG00000019991 ENSG00000138798 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC6943215__F1 The ‘Metro-Rail Concept’ to targeted therapy of the pathophysiology of cirrhosis ENSG00000019991 ENSG00000170458 PMC12001479__F4 Key molecular mechanisms governing mitochondrial dynamics, biogenesis, and mitophagy ENSG00000123240 ENSG00000116688 ENSG00000198793 ENSG00000158828 ENSG00000171109 PMC3438338__F7 Interferon-Gamma-induced glial cell activation by transforming growth factor B1: A role for STAT1 and MAPK pathways ENSG00000105329 ENSG00000115415 ENSG00000175104 PMC2790720__F2 IRF4: Immunity. Malignancy! Therapy? ENSG00000101972 ENSG00000173599 ENSG00000136997 ENSG00000137265 ENSG00000104549 ENSG00000099194 ENSG00000105810 PMC5515402__F3 Differential protein expression profile in the hypothalamic GT1-7 cell line after exposure to anabolic androgenic steroids ENSG00000175946 ENSG00000027644 ENSG00000187522 ENSG00000081087 ENSG00000161944 PMC3304673__F1 Association of the canonical interferon pathway with the IRF5 haplotype ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000157601 ENSG00000185885 PMC3795344__F3 Schematic diagram illustrating a proposal for the involvement of Cdx2 during progression of cancers through the serrated pathway ENSG00000165556 ENSG00000157764 PMC7281370__F2 Carbon metabolism in Synechocystis PCC 6803 ENSG00000112367 ENSG00000197713 PMC12127422__F9 Oxy-inflammation mechanism, Nrf2 and NFKB signaling pathway and regulation of the NLRP3 inflammasome ENSG00000162711 ENSG00000171791 ENSG00000079999 PMC6421779__F1 Canonical pathway for miRNA biogenesis ENSG00000135473 ENSG00000152520 ENSG00000128191 ENSG00000113360 ENSG00000132341 PMC4073476__F3 Bile Acids are Nutrient Signaling Hormones ENSG00000169047 ENSG00000173599 PMC4353379__F2 Proteins implicated in neurodegenerative diseases are involved in multiple steps of the miRNA biogenesis pathway ENSG00000092847 ENSG00000128191 ENSG00000113360 PMC2277398__F1 MAP kinase pathway analysis of the meta-modes ENSG00000087095 ENSG00000149269 ENSG00000119408 ENSG00000175104 PMC2718437__F2A Gene Expression Changes during the Development of Acute Lung Injury Role of Transforming Growth Factor B ENSG00000049323 ENSG00000137834 ENSG00000138795 ENSG00000157933 ENSG00000005339 ENSG00000105329 ENSG00000050748 ENSG00000183691 ENSG00000120693 ENSG00000134363 ENSG00000020633 ENSG00000168610 ENSG00000137801 ENSG00000170365 ENSG00000118785 ENSG00000095739 ENSG00000177606 PMC3724417__F2 Signaling Mechanisms in Mammalian Myoblast Fusion ENSG00000104856 ENSG00000038382 ENSG00000122420 ENSG00000112964 ENSG00000070831 ENSG00000291971 ENSG00000127528 ENSG00000168036 ENSG00000167074 ENSG00000185591 ENSG00000136826 PMC4569015__F2 Control of cell cycle transcription during G1 and S phases ENSG00000112242 ENSG00000165891 ENSG00000123374 ENSG00000166278 ENSG00000282899 ENSG00000129173 PMC8143192__F3 Therapeutic Potential of HUMSCs in Female Reproductive Aging ENSG00000019991 ENSG00000198793 PMC9164040__F3 Glance at the Molecules That Regulate Oligodendrocyte Myelination ENSG00000159224 ENSG00000170775 ENSG00000077782 ENSG00000111737 PMC10920255__F1 Macrophages participate in mediating inflammatory pain in GA ENSG00000162711 ENSG00000136869 PMC9164040__F2 Glance at the Molecules That Regulate Oligodendrocyte Myelination ENSG00000173599 ENSG00000168036 PMC5864197__F7 Orai3 calcium channel and resistance to chemotherapy in breast cancer cells: the p53 connection ENSG00000175938 ENSG00000118515 ENSG00000105656 PMC8284850__F5 Intratumoural fibroblast heterogeneity in pDaC ENSG00000107562 ENSG00000115415 ENSG00000134853 ENSG00000026508 ENSG00000128342 ENSG00000164690 ENSG00000168610 PMC10920255__F2 Gut bacteria and their metabolites can reach blood vessels, exert local effects in joints, modify macrophage-mediated inflammation and influence GA pain through breaches in the intestinal barrier ENSG00000162711 ENSG00000172936 ENSG00000136869 PMC8400324__F1 Inhibitors of the PI3K/Akt/mTOR Pathway in Prostate Cancer Chemoprevention and Intervention ENSG00000198793 PMC6477749__F5 Re-analysis of 15 selected genes by KEGGpathway enrichment ENSG00000145604 ENSG00000132646 ENSG00000123374 ENSG00000164754 ENSG00000205250 ENSG00000277273 ENSG00000117399 PMC4040894__F2 Heme biosynthesis ENSG00000144659 ENSG00000135776 ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000256269 ENSG00000188690 ENSG00000115657 PMC5700962__F11 Apoptosis pathway(red, up-regulated) ENSG00000149311 ENSG00000110711 ENSG00000002330 ENSG00000102871 ENSG00000168040 ENSG00000135116 ENSG00000084774 PMC5700962__F10 Thyroid hormones pathway (red, up-regulated) ENSG00000002330 ENSG00000067057 ENSG00000285109 ENSG00000291971 PMC5700962__F13 Wnt signaling pathway pathway(red, up-regulated) ENSG00000087095 ENSG00000095739 ENSG00000134982 ENSG00000167941 ENSG00000113558 ENSG00000196470 PMC5700962__F12 Cell cycle pathway(red, up-regulated) ENSG00000145604 ENSG00000108055 ENSG00000132646 ENSG00000123374 ENSG00000205250 ENSG00000277273 ENSG00000277943 ENSG00000117399 ENSG00000276876 PMC2891151__F1 TGFB ligands signal through the type I and type II TGFB receptors ENSG00000137834 ENSG00000135446 ENSG00000136997 ENSG00000156574 ENSG00000123374 ENSG00000105810 PMC12010877__F8 Growth status of tea plants under drought stress with and without the exogenous application of tea polyphenols ENSG00000084774 PMC3233056__F7 Different expressed proteins indicated in glycolysis, TCA cycle, pentose phosphate pathway, nucleotide metabolism, amino acid metabolism, and cell wall development ENSG00000122966 ENSG00000150787 ENSG00000182667 PMC9100643__F3 Fermentative Indole Production via Bacterial Tryptophan Synthase Alpha Subunit and Plant Indole-3-Glycerol Phosphate Lyase Enzymes ENSG00000150787 PMC9490947__F8 Pregabalin mitigates microglial activation and neuronal injury by inhibiting HMGB1 signaling pathway in radiation-induced brain injury ENSG00000189403 ENSG00000136869 PMC6524185__F7 Differential genes: the PI3K-Akt signaling pathway ENSG00000177455 ENSG00000124102 ENSG00000103479 ENSG00000002330 ENSG00000198793 PMC5351668__F6 Comprehensive tissue-specific gene set enrichment analysis and transcription factor analysis of breast cancer by integrating 14 gene expression datasets ENSG00000126218 ENSG00000101000 ENSG00000133116 ENSG00000244731 ENSG00000115718 ENSG00000104368 PMC2890502__F2 The yeast MAPK signalling pathways deposited in KEGG ENSG00000137078 ENSG00000070831 ENSG00000197601 PMC4427840__F4 Pathway map of the Prtostaglandin E2 receptor signaling ENSG00000019991 ENSG00000095794 PMC5351668__F5 Comprehensive tissue-specific gene set enrichment analysis and transcription factor analysis of breast cancer by integrating 14 gene expression datasets ENSG00000157184 ENSG00000117054 ENSG00000150991 ENSG00000167114 ENSG00000134824 ENSG00000100979 ENSG00000115361 ENSG00000158874 ENSG00000069667 PMC4427840__F3 Pathway map of the histamine receptor response in dendritic cell ENSG00000140968 ENSG00000095794 PMC5822798__F1 Activation of TLRs during heart failure ENSG00000183735 ENSG00000239732 ENSG00000041982 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000164342 PMC11956240__F8 Interaction analysis of the differentially expressed proteins and metabolites involved in the top 10 enrichment pathways ENSG00000130649 ENSG00000140505 ENSG00000105607 ENSG00000138356 ENSG00000137204 ENSG00000072210 ENSG00000143149 ENSG00000173599 ENSG00000118520 ENSG00000001626 ENSG00000005187 ENSG00000036473 ENSG00000116771 ENSG00000167701 ENSG00000125166 ENSG00000151376 ENSG00000135423 ENSG00000164904 ENSG00000183077 ENSG00000076555 ENSG00000284320 ENSG00000138115 ENSG00000156096 ENSG00000073734 ENSG00000082212 ENSG00000166123 ENSG00000084774 PMC11840736__F2 Epigenetic regulation-mediated disorders in dopamine transporter endocytosis: A novel mechanism for the pathogenesis of Parkinson's disease ENSG00000073921 PMC8335696__F7 Effect of dapagliflozin on diabetic patients with cardiovascular disease via MAPK signalling pathway ENSG00000172936 ENSG00000007908 ENSG00000169032 ENSG00000162692 ENSG00000168610 ENSG00000146648 ENSG00000184216 PMC6043790__F1 Phospholipid synthesis pathways ENSG00000163624 ENSG00000146005 ENSG00000173599 PMC4661888__F3 Gene expression analysis of thyroid hormone synthesis pathway ENSG00000042832 ENSG00000140279 ENSG00000165409 ENSG00000140274 PMC4573710__F12 Proposed model of HDAC10 regulation in G2/M transition ENSG00000100429 ENSG00000145386 PMC4531432__F1 Signaling pathway by which GUTK inhibited tumor metastasis in HCC (for abstract PS01-001) ENSG00000070831 ENSG00000163914 PMC4637208__F4 Proteomic identification of prognostic tumour biomarkers, using chemotherapy-induced cancer-associated fibroblasts ENSG00000003056 ENSG00000131473 ENSG00000123130 ENSG00000067057 ENSG00000116005 ENSG00000138495 ENSG00000197746 ENSG00000112561 ENSG00000169710 ENSG00000198721 ENSG00000117054 ENSG00000074800 ENSG00000198380 ENSG00000100412 ENSG00000284099 ENSG00000082212 ENSG00000091140 ENSG00000138760 PMC3891361__F8 Involvement of the Notch pathway in terminal astrocytic differentiation: role of PKA ENSG00000148400 ENSG00000131095 ENSG00000273529 PMC8980269__F1 PI3K/Akt/mTOR Signaling Pathway: Role in Esophageal Squamous Cell Carcinoma, Regulatory Mechanisms and Opportunities for Targeted Therapy ENSG00000105993 ENSG00000211445 ENSG00000168283 ENSG00000143194 ENSG00000065328 ENSG00000141424 ENSG00000140575 ENSG00000198793 ENSG00000137575 ENSG00000165795 ENSG00000137142 PMC8980269__F2 PI3K/Akt/mTOR Signaling Pathway: Role in Esophageal Squamous Cell Carcinoma, Regulatory Mechanisms and Opportunities for Targeted Therapy ENSG00000155792 ENSG00000167965 PMC4637208__F2 Proteomic identification of prognostic tumour biomarkers, using chemotherapy-induced cancer-associated fibroblasts ENSG00000165983 ENSG00000127948 PMC9550351__F1 Emerging roles of microRNAs in the regulation of Toll-like receptor (TLR)-signaling ENSG00000174125 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000175104 ENSG00000276561 PMC8699891__F5 Molecular Basis of Accelerated Aging with Immune Dysfunction-Mediated Inflammation (Inflamm-Aging) in Patients with Systemic Sclerosis PMC8984994__F1 Advances in understanding of the innate immune response to human norovirus infection using organoid models ENSG00000159128 ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000027697 ENSG00000142166 PMC9016280__F2 Mitochondria and Other Organelles in Neural Development and Their Potential as Therapeutic Targets in Neurodegenerative Diseases ENSG00000002330 ENSG00000198793 ENSG00000096717 PMC5499780__F1 Action of lenvatinib and everolimus.Notes: Lenvatinib inhibits RTKs on endothelial cell and cancer cell ENSG00000134086 ENSG00000198793 PMC4643792__F3 Dietary phytochemical alters caste-associated gene expression in honey bees ENSG00000142192 ENSG00000146648 PMC9313263__F6 High Oxytocin Receptor Expression Linked to Increased Cell Migration and Reduced Survival in Patients with Triple-Negative Breast Cancer ENSG00000138798 ENSG00000146648 PMC5615248__F2 Regulation diagram ENSG00000148400 ENSG00000106003 PMC3084093__F4 Proteins encoding the CAF and tumor stroma-associated genes from seven different epithelial tumors share common involvement in the MAPK signaling pathway and focal adhesion ENSG00000110799 ENSG00000150093 ENSG00000168036 ENSG00000127191 ENSG00000115232 ENSG00000146648 ENSG00000197461 ENSG00000160691 PMC4473262__F4 Human Blood Metabolome-Transcriptome Interface ENSG00000173599 ENSG00000115718 PMC3636692__F3 The VEGF-DLL4-Notch signaling pathway in angiogenic sprouts ENSG00000118257 PMC9006576__F1 Emerging role of RNA sensors in tumor microenvironment and immunotherapy ENSG00000183735 ENSG00000088888 ENSG00000167207 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC5243832__F1 Activation and regulation of complement pathways relevant to Borrelia spp ENSG00000113600 ENSG00000291559 ENSG00000197971 ENSG00000244731 ENSG00000166278 ENSG00000182326 ENSG00000236625 PMC6119098__F4 E-cadherin in Contact Inhibition and Cancer ENSG00000134982 ENSG00000168036 PMC6119098__F2 Regulation of the Hippo signaling pathway ENSG00000129474 ENSG00000186575 ENSG00000130545 ENSG00000109321 ENSG00000291971 ENSG00000168036 ENSG00000132849 ENSG00000072415 PMC11172217__F10 FGF5 promoting secondary hair follicle growth ENSG00000019991 ENSG00000138795 ENSG00000155011 ENSG00000015285 ENSG00000168036 ENSG00000108375 ENSG00000185269 ENSG00000077782 PMC10741648__F1 Reelin signaling pathway ENSG00000291971 ENSG00000099942 ENSG00000173406 PMC5448101__F8 Ubiquitin editing in the Imd-signaling pathway ENSG00000112977 ENSG00000168040 PMC9128178__F7 Serial circulating tumor DNA monitoring of CDK4/6 inhibitors response in metastatic breast cancer ENSG00000135446 ENSG00000138395 ENSG00000136997 ENSG00000105810 PMC7650809__F1 CTLA-4 pathway: (A) T cell activation in response to the tumor-associated antigen requires 2 signals PMC5789329__F5A Interplay between Selenium Levels and Replicative Senescence in WI-38 Human Fibroblasts: A Proteomic Approach ENSG00000163421 PMC9243315__F3 Paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine ENSG00000171246 ENSG00000020633 ENSG00000168036 ENSG00000146648 ENSG00000179399 PMC9243315__F2 Paradoxical roles of miR-4295 in human cancer: Implications in pathogenesis and personalized medicine ENSG00000171246 ENSG00000124882 ENSG00000173599 ENSG00000145321 ENSG00000020633 ENSG00000168036 ENSG00000048028 ENSG00000112715 ENSG00000100485 ENSG00000146648 ENSG00000179399 PMC10036653__F8 ER stress induces upregulation of transcription factor Tbx20 and downstream Bmp2 signaling to promote cardiomyocyte survival ENSG00000164532 PMC7847674__F2 Signal transduction mechanisms activated by ovarian steroid hormones on endometrial autophagy ENSG00000177169 ENSG00000082175 PMC4728676__F1 Molecular and cellular mode of action of energy disruptors ENSG00000092621 ENSG00000110931 PMC4227529__F1 Metabolic shifts through the hexosamine biosynthesis pathway (HBP) and protein O-GlcNAcylation in cancer ENSG00000147162 ENSG00000198408 PMC3821664__F4 Biosynthetic pathway of major phospholipids in vascular endothelial tissue and mononuclear leukocytes ENSG00000042832 ENSG00000173599 PMC8649922__F1 Microenvironmental Factors Modulating Tumor Lipid Metabolism: Paving the Way to Better Antitumoral Therapy ENSG00000131473 ENSG00000135218 ENSG00000130164 ENSG00000042832 ENSG00000113161 ENSG00000169710 ENSG00000096717 PMC5107940__F7 Proteomic adaptation of small intestinal mucosa in response to dietary protein limitation ENSG00000288292 ENSG00000086730 PMC9657665__F1 Cellular Senescence in Metabolic-Associated Kidney Disease: An Update ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000096717 PMC3303935__F1 Toll-Like Receptors in Chronic Pain ENSG00000169245 ENSG00000226275 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000125538 ENSG00000189403 ENSG00000169429 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC3259275__F2 ATM interaction with metabolic signaling pathways ENSG00000149311 ENSG00000140443 PMC10979625__F8 Brief figure summarizes the FGF2-FGFR1-p21 regulatory pathway in FGFR1 amplified ER + BC cells ENSG00000077782 ENSG00000168610 PMC5908125__F9 Glyoxalase 1 (Glo1) sustains the metastatic phenotype of prostate cancer cells via epithelial‐to‐mesenchymal transition (EMT) control: involvement of miR‐101, hydroimidazolone (MG‐H1), argpyrimidine (AP) and TGF‐B1/Smads signalling pathway PMC9223569__F1 Involvement of Ceramide Signalling in Radiation-Induced Tumour Vascular Effects and Vascular-Targeted Therapy ENSG00000100422 ENSG00000119537 ENSG00000174607 ENSG00000102172 PMC7520695__F3 Signaling pathway of IL-1B and IL-18 ENSG00000172936 ENSG00000175104 ENSG00000115594 PMC7520695__F2 Canonical pathway and activation mechanism of inflammasomes and outcomes in cancer ENSG00000278718 ENSG00000162711 ENSG00000172936 PMC11725820__F1 Canonical type I IFN signaling pathway ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000147896 ENSG00000142166 PMC7240857__F1 Different expression of MAPK8 in breast cancer samples to normal samples ENSG00000213996 ENSG00000111057 ENSG00000105550 ENSG00000138798 ENSG00000130649 ENSG00000198793 ENSG00000087586 ENSG00000169710 ENSG00000112715 ENSG00000118777 ENSG00000183765 ENSG00000082175 ENSG00000136997 ENSG00000104918 ENSG00000123374 ENSG00000167701 ENSG00000104899 ENSG00000189058 ENSG00000010704 ENSG00000132693 ENSG00000087460 ENSG00000149311 ENSG00000138207 ENSG00000138823 ENSG00000163235 ENSG00000146648 ENSG00000127948 PMC5367651__F4 Diagrammatic scheme depicting potential survival pathway-related gene targets of the downregulated microRNAs and their signaling pathways in prostate cancer cells ENSG00000117020 ENSG00000002330 ENSG00000005339 ENSG00000109320 ENSG00000150907 ENSG00000198793 ENSG00000269335 ENSG00000115904 ENSG00000171791 ENSG00000197461 PMC5367651__F3 Diagrammatic scheme depicting targeted p53 pathway-related genes by upregulated miRNAs in prostate tumor cells ENSG00000149311 ENSG00000132906 ENSG00000172667 ENSG00000105327 ENSG00000112378 PMC6515203__F5 Main signaling pathways activated by growth factor signaling through receptor tyrosine kinases (RTK) and the importance of Mg2+ ENSG00000291971 ENSG00000168610 ENSG00000146648 PMC5883056__F8 Compound 1G with the intermediate signaling pathway ENSG00000145604 ENSG00000138798 ENSG00000113558 ENSG00000185591 ENSG00000146648 PMC5883056__F7 Signal transduction Pathway analysis of the possible drug target FGR, ESR1 and GCRA and their localization ENSG00000077782 PMC2677552__F3 PharmGKB pathway diagrams ENSG00000108786 ENSG00000165841 ENSG00000197408 PMC4209605__F1 Cutting the brakes and flooring the gas: how TMEPAI turns TGFB into a tumor promoter ENSG00000163914 ENSG00000136997 PMC5831574__F8 Analyses of the potential molecular mechanisms of EPB41L4A-AS2 by a bioinformatics-based method ENSG00000156735 ENSG00000149212 ENSG00000186340 ENSG00000128594 ENSG00000160551 ENSG00000198793 ENSG00000173578 ENSG00000169860 ENSG00000067900 ENSG00000204217 PMC7527411__F7 Proposed model of maternal combination exposed diet effects on cardiac network signaling in offspring ENSG00000198793 ENSG00000132170 PMC9012636__F14 Study on the Mechanism of Üstikuddus Sherbiti in Ischemic Cerebrovascular Diseases: Based on Network Pharmacology ENSG00000101751 ENSG00000041982 ENSG00000108821 PMC7763629__F2 RTKs (EGFR) signal transduction and are a target site for small molecule and monoclonal antibody in glioma treatment ENSG00000198793 ENSG00000146648 PMC11998497__F9 PRRSV nsp5 protein interaction that accelerates the ubiquitination and degradation of Nrf2, thereby antagonizing its antiviral activity ENSG00000213928 ENSG00000105397 ENSG00000181019 ENSG00000109320 ENSG00000173039 ENSG00000079999 PMC8666006__F7 MLH1−/−-mediated cGAS activation and immunotherapy ENSG00000164430 ENSG00000051180 PMC3326558__F8 Schematic illustrating estrogen-dependent regulation of miRNA (miR)-34b expression, its target genes and tumor growth PMC4743853__F6 Stable Ectopic Expression of ST6GALNAC5 Induces Autocrine MET Activation and Anchorage-Independence in MDCK Cells ENSG00000019991 PMC5754244__F7 MUC1-C INDUCES PD-L1 AND IMMUNE EVASION IN TRIPLE-NEGATIVE BREAST CANCER ENSG00000168283 ENSG00000136997 PMC2676316__F2 Isoprenoid Metabolism and the Pleiotropic Effects of Statins ENSG00000108828 PMC1856251__F3 Molecular characterisation of non‐absorptive and absorptive enterocytes in human small intestine ENSG00000105329 ENSG00000134982 ENSG00000184182 ENSG00000197629 ENSG00000250254 ENSG00000145386 ENSG00000118971 ENSG00000166851 ENSG00000134480 ENSG00000276876 ENSG00000183765 ENSG00000175054 ENSG00000116670 ENSG00000081377 ENSG00000123374 ENSG00000105810 ENSG00000139687 ENSG00000117399 ENSG00000149311 ENSG00000145604 ENSG00000094804 ENSG00000134057 ENSG00000135446 ENSG00000132646 ENSG00000140326 ENSG00000147082 ENSG00000175305 PMC6304355__F5 Distribution of target proteins of SBD on the compressed ‘NSCLC-pathway.’ Four pathways form the tubular NSCLC pathway ENSG00000132906 ENSG00000175054 ENSG00000070831 ENSG00000138798 ENSG00000168610 ENSG00000146648 ENSG00000164305 PMC7055240__F3 Cholesterol biosynthesis pathway and gene expression identified through RNA-seq ENSG00000131473 ENSG00000160752 ENSG00000110921 ENSG00000132196 ENSG00000116133 ENSG00000172893 ENSG00000113161 ENSG00000167508 PMC4818393__F4 Integrative analysis of pathway features and the associated metabolites ENSG00000116761 PMC11353016__F2 Molecular drivers regulating hair follicle fate specification and the initiation of its growth ENSG00000138795 ENSG00000135960 ENSG00000078579 ENSG00000168036 ENSG00000164690 ENSG00000197461 PMC9402976__F5 Review of granulocyte colony-stimulating factor receptor signaling and regulation with implications for cancer ENSG00000105397 ENSG00000185591 ENSG00000168610 PMC7970325__F14 Statistically significantly enriched gene ontology (GO) molecular processes (GO-terms) identified for 871 differential genes between radioiodine resistant cancers and other thyroid cancer samples ENSG00000151632 ENSG00000182934 ENSG00000145428 ENSG00000165568 ENSG00000114698 ENSG00000124702 ENSG00000141314 ENSG00000187134 ENSG00000100253 ENSG00000135924 ENSG00000112414 ENSG00000065485 ENSG00000175215 ENSG00000100219 ENSG00000128228 PMC9402976__F2 Review of granulocyte colony-stimulating factor receptor signaling and regulation with implications for cancer ENSG00000110395 ENSG00000168610 PMC7970325__F10 Reconstructed differential DNA repair molecular network for the comparison of Papillary cancer (PC) vs Follicular adenoma (FA) ENSG00000104884 ENSG00000213928 ENSG00000142453 ENSG00000108654 ENSG00000080546 ENSG00000276876 ENSG00000012048 ENSG00000105486 ENSG00000177595 ENSG00000132781 ENSG00000144554 ENSG00000076924 ENSG00000104320 ENSG00000108384 ENSG00000136997 ENSG00000064012 ENSG00000166169 ENSG00000109674 ENSG00000292286 ENSG00000284832 ENSG00000085117 ENSG00000109321 ENSG00000181544 ENSG00000115392 ENSG00000187741 ENSG00000112039 ENSG00000107175 ENSG00000127334 ENSG00000134574 ENSG00000132646 ENSG00000167986 ENSG00000112378 ENSG00000172977 ENSG00000146648 ENSG00000156273 ENSG00000204397 ENSG00000275679 ENSG00000083093 ENSG00000284238 ENSG00000172613 ENSG00000070831 ENSG00000129355 ENSG00000196470 ENSG00000256683 ENSG00000206075 ENSG00000175054 ENSG00000276618 ENSG00000132604 ENSG00000113318 ENSG00000123415 ENSG00000139372 ENSG00000129071 ENSG00000189403 ENSG00000185591 ENSG00000051180 ENSG00000177519 ENSG00000177084 ENSG00000115107 ENSG00000253729 ENSG00000136492 ENSG00000185379 ENSG00000005339 ENSG00000197275 ENSG00000175793 ENSG00000064393 ENSG00000127191 ENSG00000149311 ENSG00000172667 ENSG00000128272 ENSG00000177606 ENSG00000161513 ENSG00000197299 ENSG00000140398 ENSG00000288325 ENSG00000095002 ENSG00000113360 PMC8645759__F8 Notch‐1 signaling promotes reattachment of suspended cancer cells by cdc42‐dependent microtentacles formation ENSG00000094631 ENSG00000070831 ENSG00000148400 PMC10755271__F6 Network pharmacology and experimental evidence: MAPK signaling pathway is involved in the anti-asthma roles of Perilla frutescens leaf ENSG00000140992 ENSG00000109320 ENSG00000078369 ENSG00000291971 ENSG00000169032 ENSG00000112715 ENSG00000105639 ENSG00000122194 ENSG00000010671 ENSG00000179295 ENSG00000180210 ENSG00000277571 ENSG00000115415 ENSG00000128052 ENSG00000177606 ENSG00000118520 ENSG00000100985 ENSG00000146648 ENSG00000186469 PMC3972113__F13 Overexpression of miR-125a in Myelodysplastic Syndrome CD34+ Cells Modulates NFKB Activation and Enhances Erythroid Differentiation Arrest ENSG00000174125 ENSG00000118503 ENSG00000172936 ENSG00000150455 ENSG00000175104 PMC10502012__F5 Proposed mechanism for PHT1 mode of action ENSG00000239732 ENSG00000167207 ENSG00000120280 ENSG00000172936 ENSG00000106100 PMC11997203__F1 PI metabolism and the PI3K/AKT signaling pathway in cell dynamics ENSG00000291802 ENSG00000171100 ENSG00000040933 ENSG00000115020 ENSG00000081277 ENSG00000148384 ENSG00000151151 PMC4152414__F2 Coactivator dependent signaling regulates various biological functions, and deregulation causes diseases PMC8516775__F6 Bile acids increase intestinal marker expression via the FXR/SNAI2/miR-1 axis in the stomach ENSG00000094631 ENSG00000165556 ENSG00000136826 ENSG00000293532 PMC11898953__F9 Lycorine hydrochloride Suppresses the Proliferation and Invasion of Esophageal Cancer by Targeting TRIM22 and Inhibiting the JAK2/STAT3 and Erk Pathways ENSG00000198793 ENSG00000168610 PMC11831486__F3 Tumor type‐specific protein network profile ENSG00000160789 ENSG00000111057 ENSG00000044115 ENSG00000169862 ENSG00000291971 ENSG00000198793 ENSG00000124126 ENSG00000176533 ENSG00000242616 ENSG00000171345 ENSG00000137801 ENSG00000186340 ENSG00000108821 ENSG00000292332 ENSG00000136068 ENSG00000167414 ENSG00000198561 ENSG00000164171 ENSG00000092199 ENSG00000139219 ENSG00000117020 ENSG00000069482 ENSG00000171914 ENSG00000105723 ENSG00000186469 PMC7697405__F2 Simplified schematic representation of the hyperactivated mammalian target of rapamycin (mTOR) signaling due to seizures ENSG00000198793 PMC9020238__F2 Hepatitis C virus core protein: Not just a nucleocapsid building block, but an immunity and inflammation modulator ENSG00000174125 ENSG00000172936 ENSG00000175104 PMC11997203__F5 PIPn signaling at the cytoskeleton in the regulation of cell dynamics ENSG00000070831 ENSG00000110274 PMC8355620__F4 Eccrine Sweat Gland and Its Regeneration: Current Status and Future Directions ENSG00000170365 ENSG00000281324 ENSG00000186197 ENSG00000162337 ENSG00000135960 ENSG00000134982 ENSG00000166813 ENSG00000136997 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC6998363__F5 hsa-miR-4638-3p and hsa-miR-1273 g-3p Target Gene Network Map ENSG00000107779 ENSG00000137713 ENSG00000137834 ENSG00000259207 ENSG00000140795 ENSG00000134215 ENSG00000139269 ENSG00000156574 ENSG00000115904 ENSG00000077157 ENSG00000118707 ENSG00000067900 ENSG00000145431 ENSG00000117020 ENSG00000148082 ENSG00000010810 ENSG00000171914 ENSG00000135503 ENSG00000146648 ENSG00000204217 ENSG00000125968 ENSG00000140443 ENSG00000114739 PMC9376100__F4 Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) ENSG00000118503 ENSG00000026103 PMC9376100__F6 Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) ENSG00000099985 ENSG00000137070 ENSG00000198793 ENSG00000163914 ENSG00000168036 ENSG00000121807 ENSG00000168610 PMC4699200__F9 TGRL Lipolysis Products Induce Stress Protein ATF3 via the TGFB Receptor Pathway in Human Aortic Endothelial Cells ENSG00000162772 PMC2670967__F2 Schematic (simplified) representation of enzymatic and metabolite components of the liver methionine metabolic pathway, and the influence of ethanol consumption PMC9347431__F5 Coronavirus disease 2019 and pityriasis rosea: A review of the immunological connection ENSG00000169245 ENSG00000186810 ENSG00000088888 ENSG00000105397 ENSG00000115415 PMC4705964__F8 Working model for Gpr175 function as an enhancer of Hh signaling ENSG00000128602 PMC4788539__F7 Schematic model recapitulating the role Shoc2 plays in controlling ERK1/2 activity ENSG00000108679 ENSG00000138798 ENSG00000108061 PMC1974887__F1 Endogenous Synthesis of Coenzyme Q in Eukaryotes ENSG00000132423 ENSG00000119723 ENSG00000110871 ENSG00000173085 PMC5858900__F1 Multifaceted Fanconi Anemia Signaling ENSG00000131944 ENSG00000144554 ENSG00000187790 ENSG00000187741 ENSG00000197299 ENSG00000112039 ENSG00000158169 PMC6315117__F4 Pathway analysis graph of G1/S checkpoint ENSG00000149311 ENSG00000175054 ENSG00000168283 ENSG00000101945 ENSG00000169375 PMC11599189__F2 Figure illustrates the various functions and molecular interactions of circFOXP1 in cellular processes ENSG00000178860 ENSG00000011304 ENSG00000198793 ENSG00000117139 ENSG00000168610 PMC3128904__F2 NOD-like receptor (NLR) family and inflammasome ENSG00000167207 ENSG00000187796 ENSG00000106100 PMC3128904__F1 Toll-like receptor (TLR) signaling pathway ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC12030433__F5 Carotenoid metabolic pathway ENSG00000090402 ENSG00000173992 ENSG00000127948 PMC6991631__F7 Proposed model of mifepristone for the treatment of adenomyosis ENSG00000170558 ENSG00000123374 ENSG00000121966 PMC3374974__F2 EphA Receptor Signaling – Complexity and Emerging Themes ENSG00000142627 ENSG00000198793 ENSG00000164327 PMC7384889__F4 Bone biology: insights from osteogenesis imperfecta and related rare fragility syndromes ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000125084 PMC5279903__F1 Molecular mechanisms of JNK1 and JNK2 in obesity-driven insulin resistance ENSG00000105550 ENSG00000169047 ENSG00000177606 ENSG00000134200 PMC9289261__F2 Neuroimmune Interaction in Chronic Pain: A Review on Immune Cells in Peripheral and Central Sensitization ENSG00000172936 PMC4135311__F2 Sirt1/AMPK/PGC1/PPAR signaling network ENSG00000150907 PMC3385949__F1 FOXO proteins are involved in multiple signaling pathways that control cell proliferation, apoptosis, survival, and immune functions in response to external and internal stimuli ENSG00000122025 ENSG00000138798 ENSG00000164399 ENSG00000168036 ENSG00000146648 PMC3573758__F2 Development of allergic inflammation ENSG00000033327 ENSG00000010810 ENSG00000010671 PMC3073290__F1 Models of how IFNB and GA activate PI3KD/Akt and MEK/ERK pathways to induce sIL-1Ra production in monocytes ENSG00000115415 ENSG00000142166 PMC8958363__F7 Chromosomal instability drives convergent and divergent evolution toward advantageous inherited traits in mammalian CHO bioproduction lineages ENSG00000164053 ENSG00000121578 ENSG00000105438 ENSG00000185615 ENSG00000139618 ENSG00000136731 ENSG00000175054 ENSG00000128272 ENSG00000100934 ENSG00000134574 ENSG00000144554 ENSG00000138768 ENSG00000051180 ENSG00000177239 ENSG00000100219 ENSG00000090520 ENSG00000089597 PMC9492418__F6 B-Cell Translocation Gene 2 Upregulation Is Associated with Favorable Prognosis in Lung Adenocarcinoma and Prolonged Patient Survival ENSG00000104856 ENSG00000100906 ENSG00000179912 ENSG00000073792 ENSG00000088038 PMC4253858__F1 EGFR signaling pathways and receptor cross-talk ENSG00000167601 ENSG00000019991 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC3462113__F1 Main metabolic reactions in central carbon metabolism.A) Xylose can be assimilated through two pathways: the fungal oxidoreductive pathway consisting of XR and XDH or the bacterial isomerization pathway via an XI ENSG00000197713 ENSG00000122966 ENSG00000173599 ENSG00000146701 PMC2853973__F1 Kaposi's sarcoma-associated herpesvirus and innate immunity ENSG00000169245 ENSG00000183735 ENSG00000136869 PMC6665304__F6 DISC1 at the synapse ENSG00000149269 ENSG00000154310 PMC6665304__F4 DISC1 regulates neurogenesis via Wnt/Beta-catenin signaling ENSG00000168036 PMC8469001__F6 LRP1B: A Giant Lost in Cancer Translation ENSG00000142192 ENSG00000168702 PMC5355523__F7 Putative mechanism for the interaction between miRNA and the Ago2, Pum2, and REST proteins ENSG00000084093 ENSG00000187605 ENSG00000102081 ENSG00000196591 ENSG00000038002 ENSG00000123908 ENSG00000155363 PMC6863373__F2 Skeletal Muscle Atrophy: Discovery of Mechanisms and Potential Therapies ENSG00000128272 ENSG00000088826 ENSG00000116717 PMC4633443__F1 Inflammasome axis ENSG00000273992 ENSG00000162711 ENSG00000170458 ENSG00000125538 PMC8999913__F6 Hyperosmotic Stress Induces Phosphorylation of CERT and Enhances Its Tethering throughout the Endoplasmic Reticulum ENSG00000139624 ENSG00000116649 ENSG00000143418 PMC7328520__F6 nc886 and cancer ENSG00000144895 ENSG00000136997 ENSG00000168610 PMC9537379__F3 B cell-T cell interplay in immune regulation: A focus on follicular regulatory T and regulatory B cell functions ENSG00000169047 ENSG00000110777 ENSG00000145321 ENSG00000154016 PMC4122622__F1 Crosstalk of BMP and neurotrophin signaling in neurons ENSG00000198742 PMC6354331__F5 Enrichment analysis with DAVID 6.8 of the associated genes for the 4 novel diseases and COPD ENSG00000127948 PMC9537379__F5 B cell-T cell interplay in immune regulation: A focus on follicular regulatory T and regulatory B cell functions ENSG00000115415 ENSG00000105246 ENSG00000154016 ENSG00000168610 PMC5133374__F4 Immune response_IL-17 signaling pathway ENSG00000112116 ENSG00000108688 ENSG00000185591 ENSG00000175104 ENSG00000163702 ENSG00000062485 PMC5146691__F1 Implications of cell biological processes on innate immune signaling ENSG00000170458 ENSG00000163568 ENSG00000136869 ENSG00000125347 PMC6239905__F12 Metabolisms of SGG in seminiferous tubules: interrelationship between testicular germ cells and Sertoli cells PMC4216471__F4 The molecular cascade downstream of Nodal and Activin A signalling in EpiSCs ENSG00000121989 ENSG00000087245 ENSG00000133937 ENSG00000285109 ENSG00000156574 ENSG00000168036 ENSG00000121966 ENSG00000160973 ENSG00000164736 ENSG00000123612 ENSG00000185155 ENSG00000241186 ENSG00000019549 ENSG00000135503 ENSG00000283060 ENSG00000114739 PMC7324512__F6 Vestigial-like family member 3 (VGLL3), a cofactor for TEAD transcription factors, promotes cancer cell proliferation by activating the Hippo pathway ENSG00000206538 ENSG00000150457 ENSG00000114019 ENSG00000131023 PMC2729380__F6 Expression and Functional Studies of Ubiquitin C-Terminal Hydrolase L1 Regulated Genes ENSG00000067066 ENSG00000100290 ENSG00000157933 ENSG00000092067 ENSG00000231925 ENSG00000157514 ENSG00000140464 ENSG00000089159 PMC5146691__F5 Biosynthetic pathway: nucleic acid detection from within the cytosol ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000163568 ENSG00000082512 ENSG00000163565 ENSG00000109654 ENSG00000175104 ENSG00000127191 PMC6307429__F3 Role of the NFKB pathway in the miR-155/SOCS1 axis in the immune system ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC4950325__F6 Schematic representation of the metabolic pathway leading to the activation of vitamin D3 to calcitriol ENSG00000111012 ENSG00000205221 ENSG00000019186 ENSG00000186104 ENSG00000135929 PMC7902901__F3 Merged network of Reactome pathways identified by all models (2.1 to 2.5) ENSG00000159216 ENSG00000186716 ENSG00000163914 ENSG00000105656 ENSG00000156521 ENSG00000160691 ENSG00000102977 PMC7902901__F5 Induced regulatory network of smooth muscle cell contraction ENSG00000197043 ENSG00000160973 ENSG00000005339 ENSG00000285109 ENSG00000183072 ENSG00000122786 ENSG00000185591 ENSG00000137076 ENSG00000167182 PMC4804208__F6 Metabolic flux profiling of MDCK cells during growth and canine adenovirus vector production ENSG00000122966 ENSG00000173599 ENSG00000172005 PMC4013140__F7 The Repressive Effect of miR-148a on TGF beta-SMADs Signal Pathway Is Involved in the Glabridin-Induced Inhibition of the Cancer Stem Cells-Like Properties in Hepatocellular Carcinoma Cells PMC7744575__F6 Schematic diagram illustrating the role of proteins encoded DEGs and DASGs and others on AMPA-receptor signaling and synaptic plasticity ENSG00000118160 ENSG00000105402 ENSG00000011347 PMC5089864__F1 Ongoing resolution of duplicate gene functions shapes the diversification of a metabolic network ENSG00000069482 ENSG00000169299 PMC8531299__F1 FASN and the cell death decision circuitry controlled by the BCL-2 family ENSG00000131473 ENSG00000100290 ENSG00000002330 ENSG00000169710 ENSG00000135116 ENSG00000104081 PMC5892715__F1 Breaking up with ATM ENSG00000188486 ENSG00000149311 ENSG00000112130 PMC8073244__F3 Viral Infection Modulates Mitochondrial Function ENSG00000088888 ENSG00000276561 PMC6193074__F10 Cardioprotection by AsIV through CaSR/IP3R pathway ENSG00000002330 ENSG00000285109 ENSG00000036828 ENSG00000091140 PMC11011684__F3 Gene Expression Patterns Associated with Survival in Glioblastoma ENSG00000065978 ENSG00000156076 ENSG00000198793 ENSG00000163914 ENSG00000168036 ENSG00000124181 ENSG00000146648 ENSG00000064300 PMC6959132__F4 Pathway for signaling from p75–Nogo receptor complex to RhoA ENSG00000169783 PMC3357504__F3 Translation initiation control relays signals to erythroid and granulocytic differentiation ENSG00000144895 ENSG00000186716 ENSG00000198793 PMC8432624__F2 Protein Arginine Methyltransferase 5 Functions via Interacting Proteins ENSG00000147649 ENSG00000159388 ENSG00000168036 ENSG00000172301 PMC6959132__F6 BDNF-signaling pathway mechanism ENSG00000124102 ENSG00000253506 PMC3357504__F2 Translation initiation control during growth factor stimulation, cellular stress, and cellular physiology ENSG00000165119 ENSG00000144895 ENSG00000198793 PMC4011580__F6 SCFBeta-TRCP-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway ENSG00000069869 ENSG00000100387 ENSG00000113558 PMC8432624__F5 Protein Arginine Methyltransferase 5 Functions via Interacting Proteins ENSG00000159167 ENSG00000125398 ENSG00000198793 ENSG00000168036 ENSG00000112715 ENSG00000146648 PMC2698574__F9 The VACV- and CPXV-stimulated PI3K/Akt pathway of biological relevance in spontaneously immortalized A31 and MEF cells ENSG00000002330 PMC2877703__F1 Anabolic and catabolic pathways regulating skeletal muscle mass ENSG00000163435 ENSG00000198793 PMC8685516__F1 Ectodysplasin A/Ectodysplasin A Receptor System and Their Roles in Multiple Diseases ENSG00000170365 ENSG00000135960 ENSG00000119919 ENSG00000168036 ENSG00000131323 ENSG00000175104 PMC8422731__F2 STAT3 pathway as a molecular target for resveratrol in breast cancer treatment ENSG00000291971 ENSG00000168610 ENSG00000169375 PMC8422731__F1 STAT3 pathway as a molecular target for resveratrol in breast cancer treatment ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC4233289__F2 Proposed model for the regulation of mTOR signaling in conditions of overnutrition and the cardiorenal syndrome (CRS) ENSG00000198793 PMC20438__F5 Schematic diagram of possible Rad6-mediated metabolic pathways ENSG00000132646 ENSG00000070950 PMC8528922__F3 Genes involved in the Taxol biosynthetic pathway ENSG00000197429 PMC5893168__F7 Signaling pathway predicted to be activated by the miRNA target predictor of IPA ENSG00000163464 ENSG00000081181 ENSG00000169291 ENSG00000162692 ENSG00000005381 ENSG00000084774 PMC2518924__F9 The CEBPD network ENSG00000197971 ENSG00000221869 ENSG00000131095 PMC5031950__F2 PCSK9 and apoB-containing lipoproteins metabolism ENSG00000130164 ENSG00000169174 PMC3502766__F5 Proposed metabolic pathway for the degradation of VFA and TCE inferred from the metaproteomic data PMC10931645__F2 Systematic Review of the Advances in the Study of T Lymphocyte Suppressor Receptors in HBV Infection: Potential Therapeutic Targets ENSG00000213658 ENSG00000134982 PMC10931645__F3 Systematic Review of the Advances in the Study of T Lymphocyte Suppressor Receptors in HBV Infection: Potential Therapeutic Targets ENSG00000226275 ENSG00000089692 ENSG00000153283 ENSG00000117091 ENSG00000181847 ENSG00000122223 ENSG00000134982 ENSG00000104760 ENSG00000150637 PMC5770609__F3 Crosstalk between the Hh and Wnt pathways forms regulatory loops ENSG00000106571 ENSG00000134982 ENSG00000168036 ENSG00000128602 PMC5770609__F2 Wnt signaling pathway leads to the accumulation of Beta-catenin in nucleus ENSG00000134982 ENSG00000168036 PMC7806208__F5 Pathway schematics of pharmaceutical and ligand interventions of three signaling pathways known to be active in mammalian A549 cells PMC6276890__F1 Canonical and non-canonical signaling pathways of the AhR ENSG00000140505 ENSG00000140465 ENSG00000106546 PMC6803600__F2 Immunometabolic changes associated with DC maturation ENSG00000183735 ENSG00000170458 ENSG00000125538 ENSG00000198793 ENSG00000112149 ENSG00000007171 ENSG00000090659 PMC5253683__F8 GA13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3Beta-NFATc1 signalling pathway ENSG00000120063 ENSG00000175104 ENSG00000131196 ENSG00000143387 PMC7693142__F3 Methionine and folate cycle pathways involving PLP-, FAD- and B12-dependent enzymes ENSG00000116761 PMC4091098__F1 Heat shock protein-CD91 pathway mediates tumor immunosurveillance PMC5580204__F4 Signalling pathway in normal and hyperglycemia patients ENSG00000123374 ENSG00000100985 ENSG00000047936 ENSG00000121966 PMC2788007__F1 Simplified representation of the complement cascade ENSG00000288512 ENSG00000166278 PMC6071544__F16 Mitochondrial Uncoupling Proteins: Subtle Regulators of Cellular Redox SignalingReviewing Editors: Jerzy Beltowski, Joseph Burgoyne, Gabor Csanyi, Sergey Dikalov, Frank Krause, Anibal Vercesi, and Jeremy Ward ENSG00000122966 ENSG00000172005 ENSG00000166278 ENSG00000062485 ENSG00000026103 PMC8335696__F3 Effect of dapagliflozin on diabetic patients with cardiovascular disease via MAPK signalling pathway ENSG00000149968 ENSG00000162692 ENSG00000146648 PMC8335696__F5 Effect of dapagliflozin on diabetic patients with cardiovascular disease via MAPK signalling pathway ENSG00000180210 ENSG00000117525 ENSG00000149968 ENSG00000007908 ENSG00000169032 ENSG00000037280 ENSG00000146648 PMC7940178__F1 HCA2 triggers different downstream signaling pathway in different cell types ENSG00000162711 ENSG00000002330 ENSG00000042832 PMC4491684__F1 The Hedgehog signaling pathway mechanism ENSG00000117245 ENSG00000128602 PMC5797779__F1 Biochemical function and regulation of indolamine-2,3-dioxygenase 1 (IDO1) ENSG00000100473 ENSG00000111537 ENSG00000173757 ENSG00000163599 ENSG00000129514 ENSG00000188676 ENSG00000102974 ENSG00000106546 PMC7147660__F1 PD-1/PD-L1 pathway and anti-PD-1/PD-L1 agents combination strategies in breast cancer ENSG00000135446 ENSG00000189403 ENSG00000105810 PMC12209598__F2 Redox regulation of metabolism and bioenergetics ENSG00000149311 ENSG00000162711 ENSG00000186716 ENSG00000198793 ENSG00000285482 ENSG00000005381 ENSG00000079999 PMC5817350__F2 Releases and signalling of IL-33 ENSG00000137033 ENSG00000172936 ENSG00000185187 ENSG00000175104 ENSG00000184216 PMC12209598__F4 Oxidative stress ENSG00000177169 ENSG00000197930 ENSG00000079999 PMC3674189__F7 Estrogen receptor B ligand therapy activates PI3K/Akt/mTOR signaling in oligodendrocytes and promotes remyelination in a mouse model of multiple sclerosis PMC6020165__F3 Proteasome Inhibitors: Structure and Function ENSG00000100290 ENSG00000177606 PMC7397839__F1 Metabolic Role of PTEN in Insulin Signaling and Resistance ENSG00000198793 PMC8869711__F1 Selenoprotein Tissue Homeostasis in MetS Programming: Energy Balance and Cardiometabolic Implications ENSG00000198793 PMC5341000__F6 Role of DHT- and EST-regulated proteins in energy metabolism ENSG00000185608 ENSG00000100522 ENSG00000138029 ENSG00000137275 ENSG00000197746 ENSG00000049860 ENSG00000137563 ENSG00000172340 ENSG00000127884 ENSG00000168924 ENSG00000146701 ENSG00000115419 ENSG00000084774 PMC4452412__F7 Ormeloxifene Suppresses Desmoplasia and Enhances Sensitivity of Gemcitabine in Pancreatic Cancer ENSG00000107562 ENSG00000128602 ENSG00000121966 PMC5100792__F1 Isoprenoid biosynthetic pathways and enzymes in Arabidopsis ENSG00000067064 ENSG00000197429 ENSG00000148377 PMC7295567__F1 The insulin/IGF-1 signaling pathway in regulating FoxO3 activity is conserved between C ENSG00000140992 PMC5351692__F1 Advances in sarcoma diagnostics and treatment ENSG00000002330 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000164690 ENSG00000128602 ENSG00000105723 PMC4686024__F10 Comparative Transcriptome Analysis in the Hepatopancreas Tissue of Pacific White Shrimp Litopenaeus vannamei Fed Different Lipid Sources at Low Salinity ENSG00000150991 ENSG00000100979 ENSG00000165269 PMC9637487__F3 Conservation and divergence: Regulatory networks underlying reproductive branching in rice and maize ENSG00000066336 ENSG00000132823 ENSG00000151914 ENSG00000123908 PMC9500642__F8 Lysophosphatidic Acid Promotes Epithelial–Mesenchymal Transition in Kidney Epithelial Cells via the LPAR1/MAPK-AKT/KLF5 Signaling Pathway in Diabetic Nephropathy ENSG00000198670 PMC7096759__F1 Pathway map of pyrimidine metabolism depicting de novo, salvage, and catalytic pathways ENSG00000228716 ENSG00000188641 ENSG00000142192 ENSG00000128951 ENSG00000102967 ENSG00000129187 ENSG00000284320 ENSG00000162368 ENSG00000134326 ENSG00000158825 ENSG00000188833 ENSG00000171793 ENSG00000147647 ENSG00000115419 ENSG00000084774 PMC4404599__F3 Schematic overview of some of the most significant IPA-identified, canonical host response pathways ENSG00000068079 ENSG00000163464 ENSG00000108691 ENSG00000213928 ENSG00000115415 ENSG00000232326 ENSG00000185745 ENSG00000162692 ENSG00000175104 ENSG00000121060 ENSG00000276561 PMC9515447__F4 USP13 in physiology and diseases ENSG00000183735 ENSG00000088888 ENSG00000115415 PMC7948473__F7 Proposed function and mechanism of ppGalNAc-T4 in breast cancer progression ENSG00000124216 PMC9266916__F1 Neuroimmune Mechanisms Underlying Neuropathic Pain: The Potential Role of TNF-Alpha-Necroptosis Pathway ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC4910876__F2 Mechanistic Target of Rapamycin: The grand conducTOR of metabolism and aging ENSG00000171105 ENSG00000143867 ENSG00000169047 ENSG00000155792 PMC3316754__F5 Ingenuity pathway analysis was used to create a network of biologically relevant genes regulated in response to diet for comparisons control versus diet A, control versus diet B, and diet C versus diet B ENSG00000136997 ENSG00000086758 PMC5946470__F4 CD44-mediated downstream signaling pathways ENSG00000019991 ENSG00000291971 ENSG00000157227 ENSG00000168036 ENSG00000100985 PMC7274160__F4 Possible signaling pathways of hsa-miRNA-122-3p and hsa-miRNA-200a-5p enriched by the KEGG pathway analyses ENSG00000134982 ENSG00000168036 PMC10968822__F3 Upregulation and downregulation of PD-L1 by YY1 through various factors ENSG00000100811 ENSG00000198793 ENSG00000168610 PMC12113870__F2 Hesperidin action on the NFKB signaling pathway ENSG00000102871 ENSG00000157625 ENSG00000083799 ENSG00000112186 ENSG00000154124 ENSG00000158125 PMC7780193__F1 Cell Energy Metabolism and Hyaluronan Synthesis ENSG00000109814 ENSG00000147162 ENSG00000198408 PMC7780193__F3 Cell Energy Metabolism and Hyaluronan Synthesis ENSG00000100811 ENSG00000170961 ENSG00000105329 ENSG00000125538 ENSG00000185591 ENSG00000096717 PMC6493842__F1 Schematic representation of central histaminergic components ENSG00000140287 PMC8865963__F1 Human genetics of SARS-CoV-2 infection and critical COVID-19 ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC5586499__F1 Metabolic Abnormalities and Oxidative Stress in Lupus ENSG00000198793 ENSG00000196092 ENSG00000131323 PMC12219042__F8 PKA-NFATs signaling pathway ENSG00000122180 ENSG00000166278 ENSG00000081189 ENSG00000131196 PMC2573957__F1 Association of Interacting Genes in the Toll-Like Receptor Signaling Pathway and the Antibody Response to Pertussis Vaccination ENSG00000170458 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000090376 ENSG00000186827 PMC3582569__F2 Pathways regulated or induced by the presence of a specific sugar ENSG00000074800 ENSG00000069482 ENSG00000198951 ENSG00000153574 ENSG00000047597 PMC5867295__F5 Processes of hypoxia and angiogenesis and the canonical fibroblast growth factor (FGF) signaling pathway and newly acquired insights into their relation to the development of the osteoarthritic (OA) chondrocyte hypertrophic phenotype ENSG00000139219 ENSG00000162733 ENSG00000125398 PMC6714402__F5 DEGs involved in estrogen and prostaglandin signaling pathways ENSG00000087245 ENSG00000182158 ENSG00000109320 ENSG00000291971 ENSG00000050748 ENSG00000113070 ENSG00000123104 ENSG00000107175 ENSG00000143578 ENSG00000087460 ENSG00000148082 ENSG00000174233 ENSG00000177606 PMC5867295__F4 MAP kinase and inflammatory signaling pathways ENSG00000139219 ENSG00000154736 ENSG00000135218 ENSG00000162551 ENSG00000163739 ENSG00000185591 ENSG00000096717 PMC5237206__F2 Summary of three key signaling cascades that may mediate the link between inflammation and epileptogenesis ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC5867295__F3 Canonical Ihh/PTHrP and Notch signaling pathways ENSG00000139219 ENSG00000154736 ENSG00000128272 ENSG00000106571 ENSG00000160584 ENSG00000112715 ENSG00000114315 ENSG00000128602 ENSG00000163501 PMC5867295__F2 Wnt- and TGFB superfamily signaling pathways ENSG00000132031 ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000162551 ENSG00000168036 ENSG00000104332 ENSG00000277641 ENSG00000196628 ENSG00000170365 ENSG00000125398 ENSG00000168646 ENSG00000125968 PMC5584596__F1 Duvelisib: A Phosphoinositide-3 Kinase D/G Inhibitor for Chronic Lymphocytic Leukemia ENSG00000177455 ENSG00000186716 PMC8532577__F2 Regulation on tumor metastasis by Raf kinase inhibitory protein: New insight with reactive oxygen species signaling ENSG00000019991 ENSG00000148400 ENSG00000291971 ENSG00000138798 ENSG00000168610 PMC1852551__F4 Multiple estrogen-regulated steps in the metabolisms of prostaglandin J2 and retinoic acid are implicated in estrogen-dependent growth of human uterine fibroids ENSG00000128918 ENSG00000143320 PMC2559911__F7 Model for the function of SHC-1 in IIS and JNK signaling ENSG00000160691 PMC11076791__F4 Proposed regulatory network ENSG00000163435 ENSG00000124216 ENSG00000162676 ENSG00000280610 ENSG00000156574 ENSG00000129514 ENSG00000164690 ENSG00000125084 PMC3236456__F2 Fungal cell wall pathogen-associated molecular patterns (PAMPs) and their host-pattern recognition receptors (PRRs) ENSG00000239732 PMC10854699__F2 Cachexia-related pathways in skeletal muscle: The mTOR (mechanistic Target of Rapamycin) signaling pathway, which is initiated by activated Akt and inhibits the phosphorylation of FoxO, facilitates the process of protein synthesis ENSG00000169047 ENSG00000198793 ENSG00000140443 PMC3236456__F3 Hypothetical model for a molecular chitinase response to chitin-containing pathogens or particles ENSG00000137265 ENSG00000133063 ENSG00000173039 PMC4032603__F3 KIBRA in Hippo pathway ENSG00000126016 ENSG00000186575 ENSG00000122966 ENSG00000139926 ENSG00000150457 PMC8835347__F7 Modulatory Effects of Alpha-Mangostin Mediated by SIRT1/3-FOXO3a Pathway in Oxidative Stress-Induced Neuronal Cells ENSG00000096717 PMC7248305__F2 Many functions of Ns1 and Ns2 ENSG00000213928 ENSG00000088888 ENSG00000115415 ENSG00000113520 ENSG00000276561 PMC7248305__F1 Interferon signaling pathway altered by Ns ENSG00000213928 ENSG00000088888 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC9581396__F1 Editorial: Osteoporosis, sarcopenia and muscle-bone crosstalk in COPD ENSG00000168610 ENSG00000131196 ENSG00000062485 PMC10893629__F4 Frequently altered signaling pathways in SCLC ENSG00000084093 ENSG00000151376 ENSG00000005339 ENSG00000136997 ENSG00000114978 ENSG00000164690 ENSG00000171791 ENSG00000150457 ENSG00000128602 ENSG00000131023 ENSG00000090932 ENSG00000139352 PMC4263734__F5 Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells ENSG00000087095 ENSG00000138795 ENSG00000100387 ENSG00000134982 ENSG00000147869 ENSG00000155011 ENSG00000113558 ENSG00000196470 ENSG00000168772 PMC4203741__F5 Long-HER Study: Clinical and Molecular Analysis of Patients with HER2+ Advanced Breast Cancer Who Become Long-Term Survivors with Trastuzumab-Based Therapy ENSG00000198670 ENSG00000132356 PMC7299730__F8 Serpinb6b regulation in uterine decidualization ENSG00000162552 ENSG00000087245 ENSG00000100985 PMC2772137__F4 Temporal Profiling of Rat Transcriptomes in Retinol-Replenished Vitamin A-Deficient Testis ENSG00000160752 ENSG00000112972 ENSG00000120437 ENSG00000075239 ENSG00000203857 PMC9575553__F3 Exploring anti-androgen therapies in hormone dependent prostate cancer and new therapeutic routes for castration resistant prostate cancer ENSG00000173120 ENSG00000004487 ENSG00000117139 ENSG00000125686 ENSG00000006459 PMC7151642__F3 Tumor Suppressive Roles of cGAS-STING ENSG00000164430 ENSG00000173638 ENSG00000173039 PMC7151642__F2 Independent functions cGAS and STING ENSG00000149311 ENSG00000183735 ENSG00000164430 ENSG00000173039 PMC2856900__F7 Moe and Rho1 function in apoptosis based on genetic, biochemical, and subcellular localization data ENSG00000177606 PMC7151642__F1 cGAS-STING signaling in immunity ENSG00000183735 ENSG00000173039 PMC5469704__F1 Stress-induced EGF Receptor Signaling Through STAT3 and Tumor Progression in Triple-Negative Breast Cancer ENSG00000137673 ENSG00000100985 ENSG00000168610 ENSG00000146648 PMC3083942__F3 Proposed model for Syk in mediating oxidative stress-induced calcium release ENSG00000095585 ENSG00000010671 PMC5377455__F7 Proteomic signature of muscle fibre hyperplasia in response to faba bean intake in grass carp ENSG00000157184 ENSG00000132341 PMC1434604__F1 Sites of action for reactive oxygen species in the regulation of the insulin signaling pathway ENSG00000124102 ENSG00000198793 PMC10896898__F4 Mixed and gene only representations of the original KEGG pathway ENSG00000171777 ENSG00000138193 ENSG00000166501 ENSG00000197943 ENSG00000152689 ENSG00000124181 PMC10896898__F3 Recreated RAS signaling pathway ENSG00000068028 ENSG00000183735 ENSG00000070831 ENSG00000156299 ENSG00000163914 ENSG00000115904 PMC6150107__F3 Role of HDACs and associated pathways involved in the processes of autophagy during the progression of DN ENSG00000177169 ENSG00000152348 ENSG00000171720 ENSG00000150907 ENSG00000144848 PMC5124539__F2 Role of Interleukin-18 in the Pathophysiology of Allergic Diseases ENSG00000113520 ENSG00000049768 PMC7686079__F4 APC mediates biased signaling of PAR1 ENSG00000134982 ENSG00000173599 PMC4905397__F1 Inhibition of tRNA synthetases restores glutathione from the effects of cystine deprivation in ferroptosis ENSG00000128272 ENSG00000167468 PMC9698586__F3 Renal Cell Carcinoma as a Metabolic Disease: An Update on Main Pathways, Potential Biomarkers, and Therapeutic Targets ENSG00000135218 ENSG00000042832 ENSG00000132341 PMC10985190__F2 Nerves promote tumour cell growth and survival The neural impact on tumors is mediated through sympathetic, parasympathetic, and sensory nerves, as indicated by solid lines in the diagram ENSG00000146648 ENSG00000165819 PMC6387630__F1 Representative pathway featuring multiple enzyme-/non-enzyme-assisted post-translational modifications (PTMs) that control cell-decision making ENSG00000100387 ENSG00000010810 ENSG00000079999 PMC2893682__F7 Interaction scheme of Shh and activated Beta-catenin signaling ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC3587725__F1 Regulation of AMP gene expression through the VDR or FXR pathways ENSG00000167207 ENSG00000172936 ENSG00000115594 PMC7568806__F5 Top network identified by ingenuity pathway analysis ENSG00000115163 ENSG00000138772 ENSG00000160183 ENSG00000070214 PMC10985190__F4 Communication between tumor cells and nerves facilitates tumor perineural invasion ENSG00000168329 ENSG00000107562 ENSG00000153993 ENSG00000145147 ENSG00000168036 ENSG00000004399 ENSG00000154134 ENSG00000121966 PMC7468437__F6 Gene network of “Rap1 signaling pathway” term enriched in both IgG4-RD tissue proteomic data and LSG transcriptomic dataset ENSG00000019991 ENSG00000128512 ENSG00000005961 ENSG00000082074 ENSG00000169032 ENSG00000182621 ENSG00000108518 ENSG00000137841 ENSG00000064300 ENSG00000137801 ENSG00000148498 ENSG00000117020 ENSG00000170962 ENSG00000049130 ENSG00000213445 ENSG00000166501 ENSG00000134853 ENSG00000140285 ENSG00000116991 ENSG00000146648 PMC6916202__F12 Major receptors and signaling pathways/proteins involved in atrophy and hypertrophy ENSG00000117525 ENSG00000163833 ENSG00000198793 ENSG00000169047 ENSG00000131323 ENSG00000127191 ENSG00000168610 ENSG00000140443 PMC4905226__F2 (See previous page) ENSG00000143799 ENSG00000149311 PMC2592774__F1 TLR signalling pathways ENSG00000183735 ENSG00000172005 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC8079327__F4 Dyslipidemia in breast cancer patients increases the risk of SAR-CoV-2 infection ENSG00000226275 PMC5867882__F2 Mammalian Hippo pathway ENSG00000122882 ENSG00000186575 ENSG00000109321 ENSG00000089685 ENSG00000163914 ENSG00000197905 ENSG00000026508 ENSG00000139926 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC6642550__F9 Peripheral and central compensatory mechanisms for impaired vagus nerve function during peripheral immune activation ENSG00000150782 ENSG00000125538 PMC6232290__F2 IL-13 signaling mechanisms in the treatment of ulcerative colitis ENSG00000123496 ENSG00000113520 ENSG00000131724 PMC7981165__F2 PI3K/AKT-dominated signaling pathway regulates RUNX2 in PCa ENSG00000150907 PMC7052942__F2 Verified signaling pathways of YWHAZ in HCC ENSG00000167601 ENSG00000144848 PMC6739099__F8 Identification of DEGs relevant to protein processing in the endoplasmic reticulum pathway ENSG00000128272 ENSG00000100387 ENSG00000076641 ENSG00000198168 PMC7673349__F2 Hypoxia regulates CSCs with HIF-1 as the core ENSG00000026508 ENSG00000164690 PMC3577660__F8 Regulation of proteins translation in Jurkat cells ENSG00000163435 ENSG00000198793 ENSG00000107581 PMC5490919__F1 Capsaicinoid biosynthetic pathway ENSG00000062485 ENSG00000026103 PMC9531712__F1 Targeting ligand-dependent wnt pathway dysregulation in gastrointestinal cancers through porcupine inhibition ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000070831 ENSG00000100592 ENSG00000134982 ENSG00000177606 ENSG00000185483 ENSG00000168036 PMC10917983__F3 Acrylamide promoted cell apoptosis via the miR-27a-5p-Btf3-ATM-p53 signaling pathway, adapted from Zhang et al ENSG00000143799 ENSG00000149311 ENSG00000145741 ENSG00000110717 PMC10917983__F2 Biogenesis and mechanism of miRNAs ENSG00000135473 ENSG00000152520 ENSG00000114127 ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC8395761__F2 Insights on Metabolic Reprogramming and Its Therapeutic Potential in Acute Leukemia ENSG00000060982 ENSG00000198793 ENSG00000115419 PMC7917119__F9 Proposed model for the mechanism by which induced miR-2187 negatively regulates NFKB and IRF3 signaling expression by targeting TRAF6, thereby avoiding excessive inflammation and immune responses ENSG00000088888 ENSG00000187608 ENSG00000125538 ENSG00000157601 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC7999827__F4 Apoptosis and cell death pathway ENSG00000026103 PMC9284064__F2 Intestinal Mucosal Barrier in Autoimmune Disease: A Potential Target ENSG00000186810 ENSG00000172936 ENSG00000146648 PMC7606733__F5 Enrichment of the Hippo signaling pathway in CCA ENSG00000126016 ENSG00000109321 ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000081051 ENSG00000132849 ENSG00000168646 ENSG00000169435 ENSG00000125968 PMC11551672__F1 Under the tumor microenvironment, abnormally activated wingless/integrated signaling pathway in cancer cells can be interpreted as an M2-tumor-associated macrophage polarization mediator ENSG00000134982 ENSG00000168036 PMC4747576__F6 Global MicroRNA Expression Profiling of Mouse Livers following Ischemia-Reperfusion Injury at Different Stages ENSG00000243414 ENSG00000170458 ENSG00000177606 ENSG00000185187 ENSG00000150455 ENSG00000076604 PMC7460598__F4 Proposed mechanism by which LOXL2 causes fibrosis and cardiac dysfunction ENSG00000134013 ENSG00000198793 PMC6139299__F1 Schematic overview of light-regulated translational control pathways in the SCN ENSG00000146469 ENSG00000198793 PMC4137540__F2 Figures accompanying the sensitivity analysis ENSG00000039537 ENSG00000113600 ENSG00000171791 PMC7937931__F4 ERBB2/VEGFA-AKT-PI3K-VEGFR signaling pathway and autocrine VEGFA signaling loop ENSG00000198793 ENSG00000112715 ENSG00000146648 ENSG00000140443 PMC4854551__F8 Proposed model for the involvement of the EIF2AK4-EIF2A-ATF4 pathway in autophagy response to AIEC infection in intestinal epithelial cells ENSG00000128272 ENSG00000144895 ENSG00000144848 ENSG00000284099 ENSG00000128829 PMC7937931__F3 Relationship between genes and their genetic functions ENSG00000002330 ENSG00000145147 ENSG00000134982 ENSG00000291971 ENSG00000138798 ENSG00000129514 ENSG00000171791 ENSG00000112715 ENSG00000103490 ENSG00000078900 ENSG00000136997 ENSG00000170430 ENSG00000100219 ENSG00000139687 ENSG00000125968 ENSG00000140443 ENSG00000124102 ENSG00000087245 ENSG00000073756 ENSG00000068028 ENSG00000149311 ENSG00000160180 ENSG00000177606 ENSG00000107485 ENSG00000146648 ENSG00000127948 PMC5123285__F8 LRRC4 as a tumor suppressor in glioblastoma ENSG00000128594 ENSG00000138798 ENSG00000146648 PMC11598914__F2 Various interactions between RABV proteins and interferon signaling pathway ENSG00000183735 ENSG00000213928 ENSG00000187608 ENSG00000115415 ENSG00000125347 ENSG00000276561 ENSG00000140464 PMC3965205__F1 Hypothetical mechanisms of tolerance within the TLR4 pathway ENSG00000111537 ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC11012138__F3 Oxygen sensing and HIF pathway activation in embryonic neurogenesis ENSG00000183734 ENSG00000168036 ENSG00000064195 PMC4403761__F1 S-nitrosylation in NFKB signaling ENSG00000102871 ENSG00000138798 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000127191 PMC5663315__F1 Schematic representation of the mTOR signaling pathway before discovery of TSC function ENSG00000106070 ENSG00000169047 ENSG00000198793 ENSG00000168610 PMC7432147__F4 Direct regulatory function of linc-ROR in various cancers ENSG00000198793 ENSG00000164086 PMC3180062__F8 Schematic Model of apoptotic signaling induced by targeting EphA2 gene by siRNA in MMC ENSG00000132906 ENSG00000142627 ENSG00000168040 ENSG00000164305 PMC5307469__F7 Role of ATF5 in the survival of B cells during stress ENSG00000128272 ENSG00000169136 ENSG00000139515 PMC3272682__F1 Recognition of Pathogenic Nucleic Acids by Patterns Recognition Receptors and Signaling ENSG00000105656 ENSG00000172936 ENSG00000164342 PMC3630382__F10 "Cell Death and Survival, Cell Cycle, Cell-to-Cell Signaling and Interaction, Cellular Movement" Network ENSG00000171403 ENSG00000006788 ENSG00000078814 ENSG00000143933 ENSG00000151176 ENSG00000104979 ENSG00000180071 ENSG00000186442 ENSG00000037241 ENSG00000131043 ENSG00000139133 ENSG00000156531 ENSG00000130803 ENSG00000182389 PMC10744776__F4 Anticancer properties of glycyrrhizinic acid in cervical cancer models ENSG00000002330 ENSG00000189403 ENSG00000171791 ENSG00000168040 ENSG00000114315 PMC11509893__F2 Possible mechanisms involved in the therapeutic effect of acacetin on liver disease ENSG00000198793 ENSG00000136869 ENSG00000168610 PMC4324923__F2 Current model of NLRP3 inflammasome activation in RPE ENSG00000162711 ENSG00000185515 ENSG00000197713 ENSG00000172936 PMC3060774__F3 Chromatin remodelling during development ENSG00000071655 ENSG00000171634 PMC7575966__F1 Enzymes and intermediate products of the heme synthesis pathway ENSG00000066926 ENSG00000126088 ENSG00000188690 PMC4589461__F1 Negative feedback regulation of bile acid metabolism: impact on liver metabolism and diseases ENSG00000160867 ENSG00000167910 ENSG00000180432 ENSG00000197063 ENSG00000135929 PMC8048169__F7 Graphical summary of the investigated signaling pathways during osteogenic differentiation of DFCs ENSG00000168036 PMC11739504__F7 Summary illustration of this study ENSG00000128602 ENSG00000281857 ENSG00000114166 PMC10780960__F3 Comparative analysis of differentially methylated regions and differentially expressed genes in the metabolism pathways related to sink-source regulation ENSG00000221818 PMC12183848__F10 Photobiomodulation mitigates blood–brain barrier disruption in APP/PS1 mouse model of Alzheimer’s disease by activating the AMPK pathway ENSG00000142192 PMC4802898__F5 Mechanism of DQP efficacy on CHD rats ENSG00000135218 ENSG00000042832 PMC3728701__F1 Musashi1 (Msi1)-dependent activation of Wnt and Notch pathways as well as of proliferation in the intestinal progenitors ENSG00000134982 ENSG00000165879 ENSG00000168036 ENSG00000133961 PMC5114345__F4 Mechanotransduction through integrins and primary cilia ENSG00000291971 ENSG00000168036 PMC9667393__F2 Increased Pi availability on cellular signaling ENSG00000176692 ENSG00000112715 PMC8787203__F5 Turning the Knobs: The Impact of Post-translational Modifications on Carbon Metabolism ENSG00000163788 PMC6087715__F1 JAK–STAT signaling and core cancer pathways ENSG00000168036 ENSG00000168610 PMC11563827__F5 Peri-implantitis involving multiple signaling pathways ENSG00000154342 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000125084 PMC9610910__F2 Protein O-GlcNAcylation in Metabolic Modulation of Skeletal Muscle: A Bright but Long Way to Go ENSG00000180210 PMC10854678__F9 Arf6 signaling pathway, the inhibitors used in this study, and a model of MuLV Gag release ENSG00000129219 ENSG00000198793 ENSG00000135404 ENSG00000165527 PMC4799985__F1 Microglial activation in models of inflammation and hypoxia: Implications for chronic intermittent hypoxia ENSG00000170458 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC4203530__F1 Dark side of Toll-like receptor signaling ENSG00000019991 ENSG00000239732 ENSG00000105329 ENSG00000291971 ENSG00000138798 ENSG00000140287 ENSG00000189403 ENSG00000172936 ENSG00000168610 PMC6549028__F1 Emerging roles of inflammasome‐dependent cytokines in cancer development ENSG00000163568 ENSG00000125538 ENSG00000163914 ENSG00000121058 ENSG00000189403 PMC8787203__F3 Turning the Knobs: The Impact of Post-translational Modifications on Carbon Metabolism ENSG00000123395 PMC12067419__F8 Possible underlying mechanism of AR inhibitors in the treatment of PAH ENSG00000074181 ENSG00000273529 PMC7016711__F4 Central carbon metabolism ENSG00000074800 ENSG00000067992 ENSG00000122966 ENSG00000092621 ENSG00000130649 ENSG00000173599 ENSG00000172005 ENSG00000146733 ENSG00000115419 ENSG00000062485 PMC3397358__F1 Viral genes and the activation of apoptosis ENSG00000144895 ENSG00000135828 ENSG00000026103 PMC4150436__F2 miRNAs involved in angiogenic process ENSG00000198793 ENSG00000105647 ENSG00000112715 PMC3199545__F1 Schematic diagram illustrating some of the major abnormalities related to sensitized D1R-signaling and associated to LID ENSG00000198576 ENSG00000101327 PMC8938720__F6 Angiopathic activity of LRG1 is induced by the IL-6/STAT3 pathway ENSG00000170365 ENSG00000091879 ENSG00000168610 PMC4702938__F3 Example of the allosteric network ‘Calcium signaling pathway’ ENSG00000196296 ENSG00000167323 ENSG00000156026 ENSG00000143933 ENSG00000087460 ENSG00000274542 ENSG00000007171 ENSG00000164742 ENSG00000108179 ENSG00000148660 ENSG00000293604 ENSG00000148680 ENSG00000196218 ENSG00000124181 PMC9589424__F3 TSH−SPP1/TRB−TSH positive feedback loop mediates fat deposition of hepatocyte: Crosstalk between thyroid and liver ENSG00000002330 ENSG00000148798 PMC3739442__F1 Accelerated aging model in HIV infection ENSG00000164151 PMC6350575__F2 Differential gene expression involved in the KEGG pathway regulated by TRF treatment, i.e., (a) cell cycle, (b) p53 signalling pathway, (c) FoxO signalling pathway, (d) Wnt signalling pathway, and (e) ErbB signalling pathway ENSG00000100387 ENSG00000177606 ENSG00000136997 ENSG00000169752 PMC6190739__F3 DNA hypermethylation, histone demethylases and histone deacetylases effect on the metabolic enzymes expression involved in glycolysis and glutaminolysis ENSG00000115548 ENSG00000134086 ENSG00000198793 ENSG00000136997 ENSG00000077463 ENSG00000142082 ENSG00000089163 ENSG00000115419 ENSG00000159399 ENSG00000107077 PMC5501999__F2 Abnormal kynurenine pathway and atherogenesis ENSG00000130164 ENSG00000042832 ENSG00000129226 ENSG00000162692 PMC6294838__F7 Signaling pathway of defensins and interleukins gene expression is regulated by PBA in porcine intestinal epithelial cells ENSG00000136869 ENSG00000146648 PMC9419495__F2 Whole Exome Sequencing in Patients With Ectopic Posterior Pituitary ENSG00000274382 ENSG00000070193 ENSG00000163666 ENSG00000170558 ENSG00000203877 ENSG00000168036 ENSG00000188095 ENSG00000164690 ENSG00000149922 PMC4253421__F7 LGR5 promotes the proliferation and tumor formation of cervical cancer cells through the Wnt/Beta-catenin signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5704268__F6 Schematic representing the in-depth molecular mechanism of the neuroprotective effect of DZ ENSG00000198793 ENSG00000171791 PMC6811524__F4 Canonical Wnt signaling manipulation during Rickettsia spp ENSG00000134982 ENSG00000168036 PMC11387478__F0 HIRI is a thorny problem after liver surgery such as liver transplantation ENSG00000153208 ENSG00000073756 PMC6811524__F3 Canonical Wnt signaling manipulation during bacterial infection of epithelial cells ENSG00000137673 ENSG00000102837 ENSG00000134982 ENSG00000168036 ENSG00000171791 PMC7588841__F2 Cancer Stem Cell Niche ENSG00000165556 ENSG00000179059 ENSG00000141448 ENSG00000285109 ENSG00000134982 ENSG00000080345 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000101115 ENSG00000203710 ENSG00000187140 ENSG00000135111 ENSG00000168610 ENSG00000136826 ENSG00000117322 ENSG00000071564 ENSG00000170365 ENSG00000163914 ENSG00000128342 PMC6811524__F6 Canonical and non-canonical Wnt signaling manipulation by pathogens occupying an extracellular niche ENSG00000147862 ENSG00000134982 ENSG00000168036 PMC10138520__F5 Lipid metabolic reprogramming in TNBC ENSG00000122691 ENSG00000288335 ENSG00000085662 ENSG00000026103 PMC3913083__F1 Signaling pathways involved in the control of skeletal muscle atrophy and hypertrophy ENSG00000169047 ENSG00000198793 ENSG00000135414 ENSG00000175390 PMC6811524__F5 Canonical and non-canonical Wnt signaling manipulation during E ENSG00000183283 ENSG00000070831 ENSG00000100592 ENSG00000134982 ENSG00000198793 ENSG00000168264 ENSG00000168036 ENSG00000049618 ENSG00000132510 PMC6811524__F2 Non-canonical/Beta-catenin-independent Wnt signaling pathways ENSG00000070831 ENSG00000100592 PMC6811524__F1 Canonical/Beta-catenin-dependent Wnt signaling ENSG00000137673 ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC4189729__F1 Synthetic lethality as a therapeutic strategy for the treatment of MMR-deficient cancers ENSG00000113318 ENSG00000095002 PMC3553670__F3 Signal transduction pathways and activation of the innate immune response ENSG00000130164 ENSG00000172005 ENSG00000172936 ENSG00000150455 ENSG00000164342 PMC6594416__F2 Autophagy signaling pathway ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000126775 ENSG00000198793 ENSG00000171791 ENSG00000168040 ENSG00000057663 ENSG00000136869 ENSG00000168404 ENSG00000145782 ENSG00000285379 ENSG00000026103 PMC3285363__F7 Hypothetical scheme illustrating a possible mechanism of mLDL-mediated regulation of C3 expression and secretion by human macrophages ENSG00000170458 ENSG00000136869 PMC6242766__F2 Animal Models to Study Bile Acid Metabolism ENSG00000180432 ENSG00000135929 PMC3316934__F4 Significant differences in mRNA expression were seen for genes involved in the JNK signaling pathway between tumors arising in different CNS locations ENSG00000102871 ENSG00000169047 ENSG00000168040 ENSG00000099942 ENSG00000127191 ENSG00000131196 PMC6594416__F3 Endoplasmic reticulum (ER) stress signaling ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC3159175__F1 Multiple TYRO3-activated pathways signaling pathways converge with transcription or activation of MITF (reproduced from Mitra et al ()), an oncogenic transcription factor often dysregulated in malignant melanoma ENSG00000092445 ENSG00000135903 ENSG00000100146 PMC87143__F6 E2F gene regulatory pathway ENSG00000112118 ENSG00000073111 ENSG00000145386 ENSG00000076003 ENSG00000117399 ENSG00000166508 ENSG00000094804 ENSG00000112242 ENSG00000135446 ENSG00000132646 ENSG00000123374 ENSG00000051180 ENSG00000282899 PMC10138520__F3 Glycolysis and its relationship with other metabolic pathways in TNBC ENSG00000092621 ENSG00000135069 ENSG00000026103 PMC3402511__F4 Novel MicroRNAs Differentially Expressed during Aging in the Mouse Brain ENSG00000140992 ENSG00000171105 ENSG00000005882 ENSG00000150907 ENSG00000198793 PMC10138520__F2 Compounds secreted by adipocytes support tumor growth, angiogenesis and metastasis ENSG00000019991 ENSG00000112715 ENSG00000168610 PMC4717906__F2 Pathway and Network Analysis of Cancer Genomes ENSG00000150938 ENSG00000144749 ENSG00000138798 ENSG00000115904 ENSG00000146648 ENSG00000101213 ENSG00000160691 PMC4189590__F7 Proposed model of the mechanisms involved in PAF-mediated EGFR transactivation in SKOV-3 ovarian cancer cells ENSG00000291971 ENSG00000113070 ENSG00000146648 PMC12187804__F2 TANs promoting the growth, proliferation and metastasis of breast cancer ENSG00000148346 ENSG00000109861 ENSG00000136869 ENSG00000100985 ENSG00000112715 ENSG00000187772 ENSG00000275565 PMC4140012__F7 (Summary illustration): Three USPs regulate Imd activation or stability and downstream signalling ENSG00000115464 ENSG00000055483 ENSG00000036672 ENSG00000162924 PMC6521226__F5 Circadian rhythm pathway identified as one of the significant pathways by the IPA ENSG00000146469 PMC4505489__F8 NAMPT inhibition leads to alterations of different metabolic pathways in cancer cells ENSG00000105835 ENSG00000146733 PMC7813845__F4 BRD4 in regulating the STING1 pathway in antiviral immunity ENSG00000141867 ENSG00000183735 ENSG00000164430 ENSG00000109320 PMC7813845__F3 Role BRD4 in regulating the NLRP3 pathway in inflammation and pyroptosis ENSG00000141867 ENSG00000162711 ENSG00000150782 ENSG00000103490 ENSG00000125538 ENSG00000173039 PMC7813845__F2 Role BRD4 in regulating the NFKB pathway in inflammation and immunity ENSG00000174125 ENSG00000141867 ENSG00000104365 ENSG00000239732 ENSG00000100906 ENSG00000109320 ENSG00000269335 ENSG00000173039 ENSG00000136869 ENSG00000213341 ENSG00000164342 PMC7025494__F1 Cytoskeletal Regulation of the Hippo pathway in Drosophila and Mammals ENSG00000129474 ENSG00000126016 PMC12193713__F5 Relationship between key genes in the biosynthetic pathways of amino acids and their derivatives and the synthesis of metabolites ENSG00000131473 ENSG00000073578 ENSG00000092621 ENSG00000135069 ENSG00000105953 ENSG00000036473 ENSG00000132840 ENSG00000146733 ENSG00000107789 ENSG00000062485 ENSG00000167701 PMC4791423__F3 Crosstalk between the TLR signaling pathway and the Notch pathway ENSG00000114315 PMC9268066__F1 Progress and Prospects of Non-Canonical NFKB Signaling Pathway in the Regulation of Liver Diseases ENSG00000104856 ENSG00000226275 ENSG00000111321 ENSG00000131323 ENSG00000127191 PMC7374090__F5 Development and implementation of the SUM breast cancer cell line functional genomics knowledge base ENSG00000126016 ENSG00000089685 ENSG00000134982 ENSG00000168036 ENSG00000081051 ENSG00000132849 ENSG00000169435 PMC9434367__F1 Inside the Noonan “universe”: Literature review on growth, GH/IGF axis and rhGH treatment: Facts and concerns ENSG00000157764 ENSG00000110395 ENSG00000115904 ENSG00000143622 ENSG00000100485 ENSG00000108061 ENSG00000196712 ENSG00000062485 ENSG00000179295 PMC7374090__F3 Development and implementation of the SUM breast cancer cell line functional genomics knowledge base ENSG00000094880 ENSG00000108055 ENSG00000176386 ENSG00000073111 ENSG00000164162 ENSG00000166851 ENSG00000117399 ENSG00000166508 ENSG00000175054 ENSG00000156970 ENSG00000100387 ENSG00000132646 ENSG00000176248 ENSG00000172005 ENSG00000198517 ENSG00000081377 ENSG00000133740 ENSG00000164754 ENSG00000147082 PMC8714916__F1 Visualizing Cancer Cell Metabolic Dynamics Regulated With Aromatic Amino Acids Using DO-SRS and 2PEF Microscopy ENSG00000150907 ENSG00000112561 ENSG00000026103 PMC8833689__F2 Obscure Potential of AHNAK2 ENSG00000168036 ENSG00000185567 ENSG00000105227 PMC5927620__F4 Metabolic pathways dysregulated in the context of disease ENSG00000148803 ENSG00000122966 ENSG00000172005 PMC4504792__F6 Methylene blue-induced neuronal protective mechanism against hypoxiareoxygenation stress ENSG00000198793 ENSG00000198125 PMC6175538__F5 Phosphoproteomic pathway analysis of heat stress induced MET signaling ENSG00000019991 ENSG00000070831 ENSG00000149269 ENSG00000132478 ENSG00000099942 ENSG00000168610 ENSG00000089159 PMC8946769__F2 NRF2 and Key Transcriptional Targets in Melanoma Redox Manipulation ENSG00000151012 ENSG00000181019 ENSG00000023909 ENSG00000079999 PMC3661706__F1 Association between TLR4 and chitinase 3-like 1 (CHI3L1/YKL-40) signaling on colonic epithelial cells in inflammatory bowel disease and colitis-associated cancer ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000185187 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC2149843__F1 A pro-adhesive PPARGamma-mediated chemokine receptor switch, CCR2→CX3CR1, in atherosclerosis ENSG00000168329 ENSG00000121807 PMC2410087__F1 Example of EGFR-mediated signaling changes, a commonly disrupted pathway in lung cancer ENSG00000070831 ENSG00000198561 ENSG00000138798 ENSG00000166484 ENSG00000168610 ENSG00000108061 ENSG00000061938 ENSG00000160691 ENSG00000115415 ENSG00000006712 ENSG00000149269 ENSG00000177606 ENSG00000106070 PMC11619119__F2 Key IFN signaling pathway targets disrupted by HBV components ENSG00000124256 ENSG00000187608 ENSG00000183486 ENSG00000157601 ENSG00000185745 ENSG00000276561 ENSG00000142166 ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000136869 ENSG00000172936 ENSG00000185591 ENSG00000131323 ENSG00000135828 ENSG00000167182 ENSG00000184216 ENSG00000164342 PMC10273736__F5 Review of Duhuo Jisheng decoction mechanisms in intervertebral disc degeneration in vitro and animal studies PMC6121355__F2 Multiple potential neuroprotective mechanisms in Shh signaling pathway ENSG00000125538 ENSG00000164690 ENSG00000128602 PMC3742659__F2 Learning and memory: an emergent property of cell motility ENSG00000138798 ENSG00000198793 ENSG00000146648 ENSG00000075213 PMC10273736__F3 Review of Duhuo Jisheng decoction mechanisms in intervertebral disc degeneration in vitro and animal studies ENSG00000087095 ENSG00000170458 ENSG00000102871 ENSG00000130522 ENSG00000172936 ENSG00000130159 ENSG00000101224 ENSG00000026103 PMC10273736__F2 Review of Duhuo Jisheng decoction mechanisms in intervertebral disc degeneration in vitro and animal studies ENSG00000242689 ENSG00000138798 ENSG00000150455 ENSG00000127191 ENSG00000095585 ENSG00000149311 ENSG00000226275 ENSG00000213658 ENSG00000135960 ENSG00000170458 ENSG00000186716 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000121060 ENSG00000184216 PMC3264680__F3 Diagram of IGF/INSR/IGF1R signaling pathway ENSG00000197081 ENSG00000140443 PMC4410894__F3 Signaling pathways involved in pluripotency ENSG00000134982 ENSG00000156574 ENSG00000168036 ENSG00000128342 PMC12004712__F9 KEGG “Cell Adhesion Molecules” pathwayKEGG “Cell Adhesion Molecules (Immune System section)” pathway highlighting the associated a) AC and b) VC contrast DEGs ENSG00000149564 ENSG00000151490 ENSG00000101751 ENSG00000169896 ENSG00000081237 ENSG00000134982 ENSG00000197471 ENSG00000121058 ENSG00000007908 ENSG00000150637 ENSG00000292348 ENSG00000188404 ENSG00000174059 PMC4277084__F3 PPAR signalling pathway ENSG00000150991 ENSG00000100979 ENSG00000165269 PMC5721794__F18 Working hypothesis regarding the mechanism by which SDF‐1A (stromal cell‐derived factor 1A) stimulates cell proliferation ENSG00000197635 ENSG00000291971 ENSG00000121966 PMC9101816__F5 Non-Cytokine Protein Profile of the Mesenchymal Stem Cell Secretome That Regulates the Androgen Production Pathway ENSG00000167601 ENSG00000087245 ENSG00000142192 ENSG00000291971 ENSG00000138798 ENSG00000120885 ENSG00000169032 ENSG00000161031 ENSG00000089159 ENSG00000038427 ENSG00000145192 ENSG00000291748 ENSG00000146648 PMC4684904__F3 Integrated, multi-cohort analysis identifies conserved transcriptional signatures across multiple respiratory viruses ENSG00000124256 ENSG00000187608 ENSG00000108679 ENSG00000138642 ENSG00000157601 ENSG00000059378 ENSG00000115267 ENSG00000291555 ENSG00000276561 ENSG00000124762 PMC10978763__F3 Polyphenols and immunomodulation: a mitochondria-centered multi-modal approach ENSG00000162711 ENSG00000186716 ENSG00000198793 ENSG00000168610 ENSG00000106546 ENSG00000026103 PMC9352453__F1 Dysregulation of the kallikrein-kinin system in bronchoalveolar lavage fluid of patients with severe COVID-19 ENSG00000130234 PMC11034561__F3 Progress in the Study of the Role and Mechanism of HTRA1 in Diseases Related to Vascular Abnormalities ENSG00000135547 ENSG00000128917 ENSG00000138798 ENSG00000146648 ENSG00000166033 PMC11034561__F2 HTRA1 can affect BrM morphology through cleavage of ECM (Fibronection) ENSG00000105329 ENSG00000166033 PMC5309409__F1 Nucleotide excision repair (NER) pathway ENSG00000012061 ENSG00000136936 PMC6174665__F2 IFNG/STAT1 and IL-6/STAT3 or IL-6/NF-IL6 signaling pathway ENSG00000111537 ENSG00000115415 ENSG00000168610 PMC4478474__F2 Gene co-expression network of the 48 genes in the peroxisome proliferator-activated receptor pathway based on their expression values ENSG00000130304 ENSG00000157184 ENSG00000166819 ENSG00000134824 ENSG00000161533 ENSG00000100979 ENSG00000197142 ENSG00000165269 ENSG00000164398 ENSG00000132170 PMC3318588__F8 Subnetwork of functional interactions of ESRP-target networks ENSG00000196411 ENSG00000175220 ENSG00000058668 ENSG00000169919 ENSG00000196586 ENSG00000109756 PMC7894481__F8 Scheme representing the effect of FGF2 on the activity of connexin hemichannels and consequences on ATP release and proliferation of cultured tanycytes ENSG00000077782 PMC12102912__F9 Mechanistic illustration: ITGB3-knockdown enhances osteogenic differentiation and radiosensitizes osteosarcoma cells via JNK/c-JUN/RUNX2 pathway activation ENSG00000259207 ENSG00000005961 PMC4506991__F7 Proposed mechanisms of bilirubin modulation of TLR4 signaling ENSG00000172936 ENSG00000136869 ENSG00000140465 ENSG00000106546 PMC4426976__F1 Can we safely target the WNT pathway? ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC3022256__F2 Patterning the DV axis in Drosophila and Tribolium ENSG00000163235 ENSG00000138798 ENSG00000163914 PMC8614623__F7 Huangkui Capsule in Combination with Leflunomide Improves Immunoglobulin A Nephropathy by Inhibiting the TGFB1/Smad3 Signaling Pathway PMC9687800__F1 Emerging Role of YAP and the Hippo Pathway in Prostate Cancer ENSG00000144560 ENSG00000131023 PMC4426976__F2 Can we safely target the WNT pathway? ENSG00000281324 ENSG00000162337 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC7432388__F2 Top two networks based on ingenuity pathway analysis (IPA) showing interactions between the controls and the case ENSG00000178860 ENSG00000133105 ENSG00000067191 ENSG00000174197 ENSG00000164093 ENSG00000168779 PMC11621763__F4 C-Myc/Max signaling pathway ENSG00000136997 ENSG00000168040 PMC8541931__F2 Molecular pathways underlying homotypic circulating tumor cell (CTC) cluster formation ENSG00000026508 ENSG00000105810 ENSG00000146648 PMC6382702__F8 Clavulanic acid biosynthesis is regulated by the TCS CagRS ENSG00000115271 ENSG00000084774 PMC4975672__F1 Xenobiotic Receptor Activation: Direct vs. Indirect ENSG00000138798 ENSG00000155974 ENSG00000146648 PMC7465958__F2 RasGRF2 as an effector of AnxA6-mediated TNBC cell growth and motility ENSG00000197043 ENSG00000070831 ENSG00000146648 PMC8575642__F1 Irisin Acts via the PGC-1A and BDNF Pathway to Improve Depression-like Behavior ENSG00000160097 PMC1533821__F2 Recognition of pathogens by cytosolic PRRs ENSG00000168040 ENSG00000106100 PMC7016605__F1 The role of the RhoA-ROCK pathway in the pathogenesis of TBI ENSG00000163914 ENSG00000169783 ENSG00000182580 PMC4635001__F1 Structural Characterisation of FabG from Yersinia pestis, a Key Component of Bacterial Fatty Acid Synthesis ENSG00000182511 ENSG00000169710 ENSG00000118520 ENSG00000280548 ENSG00000026103 PMC2882122__F4 Selection of expression patterns and activities of members of the cadherin superfamily in cancer ENSG00000166341 ENSG00000134982 ENSG00000170558 PMC3414384__F1 Actin cytoskeleton as a sensor and mediator of apoptosis ENSG00000100290 ENSG00000002330 ENSG00000120868 ENSG00000168040 ENSG00000135116 ENSG00000104081 PMC12014580__F1 Cholesterol structure, synthesis, and metabolism ENSG00000160752 ENSG00000130164 ENSG00000113161 ENSG00000104549 ENSG00000167508 PMC3092286__F1 Nonlinear signaling through the PI3K-Akt pathway PMC4176492__F2 Role of cell cycle regulators in the cellular dormancy (“intrinsic dormancy”) mechanism ENSG00000145604 ENSG00000134982 ENSG00000205250 PMC5382276__F7 A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer ENSG00000141867 ENSG00000109320 PMC7982813__F2 Cellular mechanisms and molecular pathways in Müllerian duct development ENSG00000162552 ENSG00000066468 ENSG00000170365 ENSG00000154764 ENSG00000170370 ENSG00000137090 ENSG00000276644 ENSG00000075891 ENSG00000107485 ENSG00000276799 PMC6545921__F5 Type I IFN plays an integral role in macrophage regulation of Mmp28 following stimulation with PAMP ENSG00000169245 ENSG00000105397 ENSG00000170458 ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000271447 ENSG00000150455 ENSG00000276561 ENSG00000277943 ENSG00000164342 PMC7719714__F2 O-GlcNAcylation induces the DNA damage response and proliferation in stem cells ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000147162 ENSG00000198408 PMC1964795__F5 INHIBITION OF MAPK AND STIMULATION OF AKT KINASE SIGNALING PATHWAYS: TWO APPROACHES WITH THERAPEUTIC POTENTIAL IN THE TREATMENT OF NEURODEGENERATIVE DISEASE ENSG00000002330 PMC5528622__F3 Resistance to targeted therapies in melanoma ENSG00000157764 ENSG00000146648 ENSG00000140443 PMC3680226__F6 Analysis and Prediction of Pathways in HeLa Cells by Integrating Biological Levels of Organization with Systems-Biology Approaches ENSG00000149311 PMC7719714__F1 Cellular response to stress via O-GlcNAc-dependent epigenetic regulation ENSG00000188486 ENSG00000151376 ENSG00000147162 ENSG00000198408 ENSG00000130726 PMC7509237__F6 Model highlighting the identified dual role of GPS2 during human adipocyte differentiation ENSG00000160179 ENSG00000288325 PMC3806458__F1 Scheme of the biochemical pathways leading to carotenoids and other terpenoids ENSG00000197429 PMC4366044__F4 Molecular Interaction of a Kinase Inhibitor Midostaurin with Anticancer Drug Targets, S100A8 and EGFR: Transcriptional Profiling and Molecular Docking Study for Kidney Cancer Therapeutics ENSG00000113456 ENSG00000104044 ENSG00000115232 ENSG00000089159 PMC1682017__F4 Effect of increased HER2 expression on phosphorylation sites within the EGFR signaling network ENSG00000113905 ENSG00000138798 ENSG00000089159 PMC6280363__F3 Crosstalk between surface TLRs and dysregulated metabolic factors in diabetes ENSG00000125538 ENSG00000136869 ENSG00000096717 PMC7260123__F9 BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer ENSG00000198793 ENSG00000079999 PMC5020118__F1 Innate immune dysfunction in rosacea ENSG00000104321 ENSG00000167754 ENSG00000196689 PMC7476100__F7 Mechanistic model to show how MEQ inhibits triple-negative breast cancer (TNBC) angiogenesis by regulating the MTA2/SerRS/VEGFA axis ENSG00000112715 ENSG00000283100 ENSG00000149480 PMC6014302__F4 GO enrichment of the highest score sub-modules ENSG00000131469 ENSG00000198692 ENSG00000106803 ENSG00000120705 ENSG00000164587 ENSG00000089157 ENSG00000130811 ENSG00000140612 ENSG00000278270 ENSG00000174547 ENSG00000048544 ENSG00000083845 ENSG00000037241 ENSG00000134419 ENSG00000149273 ENSG00000165502 ENSG00000124783 PMC3266027__F1 Activation of EGFR signaling in non-small-cell lung cancer (NSCLC) can occur via disruption of several different components at multiple levels of the pathway ENSG00000002330 ENSG00000163235 ENSG00000138798 PMC7998891__F6 Molecular components of BCG-driven inflammation in bladder cancer microenvironment ENSG00000163464 ENSG00000169245 ENSG00000186810 ENSG00000102962 ENSG00000138755 ENSG00000169429 PMC3561014__F2 Adjustments in root metabolism promote acclimation to deficiency ENSG00000166278 ENSG00000062485 PMC8995458__F5 Fibroblast growth factor 21 reverses high‐fat diet‐induced impairment of vascular function via the anti‐oxidative pathway in ApoE knockout mice ENSG00000105550 PMC7768820__F4 Underlying mechanism of Paeonia lactiflora P ENSG00000132906 ENSG00000184845 ENSG00000171791 ENSG00000276996 ENSG00000073756 ENSG00000064012 ENSG00000164305 ENSG00000149295 PMC6990892__F13 Pathway signaling network generated from the top-ranking 100 DM promoters ENSG00000283887 ENSG00000157500 ENSG00000177189 ENSG00000178999 ENSG00000010810 ENSG00000281877 ENSG00000285070 ENSG00000213341 ENSG00000149554 ENSG00000266964 PMC6990892__F12 Pathway signaling network generated from the top-ranking 1000 DM promoters ENSG00000070190 ENSG00000111049 ENSG00000167207 ENSG00000112559 ENSG00000172007 ENSG00000157500 ENSG00000114349 ENSG00000171720 ENSG00000240771 ENSG00000113558 ENSG00000169429 ENSG00000196639 ENSG00000105810 ENSG00000184304 ENSG00000122180 ENSG00000152332 ENSG00000119535 ENSG00000148400 ENSG00000137275 ENSG00000109321 ENSG00000108342 ENSG00000284161 ENSG00000091879 ENSG00000106100 ENSG00000143387 ENSG00000070371 ENSG00000126895 ENSG00000178568 ENSG00000140564 ENSG00000102871 ENSG00000291971 ENSG00000050748 ENSG00000005102 ENSG00000168036 ENSG00000197442 ENSG00000092820 ENSG00000010671 ENSG00000125813 ENSG00000292210 ENSG00000108840 ENSG00000182511 ENSG00000186847 ENSG00000197971 ENSG00000166501 ENSG00000189403 ENSG00000123374 ENSG00000292357 ENSG00000145782 ENSG00000139626 ENSG00000152495 ENSG00000197757 ENSG00000137193 ENSG00000135903 ENSG00000173039 ENSG00000250506 ENSG00000281877 ENSG00000090932 ENSG00000160691 ENSG00000171163 ENSG00000145604 ENSG00000149311 ENSG00000198901 ENSG00000182533 ENSG00000163435 ENSG00000177189 ENSG00000183337 ENSG00000186716 ENSG00000165409 ENSG00000143322 ENSG00000129152 ENSG00000128602 ENSG00000149554 ENSG00000105723 PMC8900870__F1 Treatment of Cerebral Ischemia Through NMDA Receptors: Metabotropic Signaling and Future Directions ENSG00000291971 ENSG00000198929 ENSG00000110218 PMC3724785__F7 Lysine-Specific Demethylase 1 (LSD1/KDM1A) Contributes to Colorectal Tumorigenesis via Activation of the Wnt/Β-Catenin Pathway by Down-Regulating Dickkopf-1 (DKK1) ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000183762 ENSG00000168036 PMC11830738__F7 Interaction between malignant T cell and CAFs with SOX4-related mechanisms in the process ENSG00000122691 ENSG00000124766 ENSG00000168036 ENSG00000168610 PMC7875961__F3 Horizontal pleiotropy of common genetic factors ENSG00000120899 ENSG00000184371 PMC2819346__F1 Hepatic Overexpression of Glycerol-sn-3-phosphate Acyltransferase 1 in Rats Causes Insulin Resistance ENSG00000173599 ENSG00000198670 PMC6207163__F2 Modulators of Redox Metabolism in Head and Neck Cancer ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC6464042__F6 mTORC pathway regulation ENSG00000143553 ENSG00000140992 ENSG00000104142 ENSG00000198793 ENSG00000164327 ENSG00000167965 ENSG00000006715 ENSG00000215305 ENSG00000103091 ENSG00000139719 ENSG00000168209 ENSG00000119487 ENSG00000116586 ENSG00000111237 ENSG00000069329 ENSG00000149357 ENSG00000085415 ENSG00000127580 ENSG00000164654 ENSG00000132842 ENSG00000079999 ENSG00000166887 ENSG00000205629 ENSG00000109270 ENSG00000164039 ENSG00000143155 ENSG00000134108 PMC2721397__F2 Key pathways in hepatocarcinogenesis and molecularly targeted agents currently under investigation in treatment of advanced HCC ENSG00000019991 ENSG00000138798 ENSG00000198793 PMC8835994__F2 MAPK/ERK Pathway as a Central Regulator in Vertebrate Organ Regeneration ENSG00000278494 ENSG00000177606 ENSG00000136997 ENSG00000171791 ENSG00000168610 ENSG00000123268 PMC4622872__F1 Pathways that play important roles in melanocyte and melanoma development ENSG00000157404 ENSG00000157764 ENSG00000135446 ENSG00000198793 ENSG00000288512 ENSG00000056558 ENSG00000105810 ENSG00000107165 ENSG00000162692 ENSG00000127191 ENSG00000100146 ENSG00000146648 PMC6320933__F3 Regulatory network of MBP-1 PMC7423166__F9 Mechanism for hepatocyte PPARA activation on BA synthesis and transport regulation ENSG00000138075 ENSG00000276559 ENSG00000167910 ENSG00000180432 ENSG00000099377 ENSG00000143921 ENSG00000135929 PMC12190794__F1 NcRNAs involved in the regulation of DIC ENSG00000223573 PMC8750350__F3 Cell Death in Hepatocellular Carcinoma: Pathogenesis and Therapeutic Opportunities ENSG00000108691 ENSG00000163739 ENSG00000129226 ENSG00000189403 ENSG00000130513 PMC4622872__F3 Epigenetic regulators as central components in melanoma signaling ENSG00000198901 ENSG00000157764 ENSG00000088305 ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC8750350__F1 Cell Death in Hepatocellular Carcinoma: Pathogenesis and Therapeutic Opportunities ENSG00000137275 ENSG00000102871 ENSG00000171791 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000064012 ENSG00000164305 ENSG00000285379 ENSG00000026103 PMC8541492__F1 COVID-19 Mortality Risk Correlates Inversely with Vitamin D3 Status, and a Mortality Rate Close to Zero Could Theoretically Be Achieved at 50 ng/mL 25(OH)D3: Results of a Systematic Review and Meta-Analysis ENSG00000111012 ENSG00000186104 PMC3504253__F1 Inactivated Wnt pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC7179660__F8 Mechanism by which DDT inhibits oxidative stress and apoptosis in PC12 cells ENSG00000096717 PMC8428888__F2 Preimmune Recognition and Response to Microbial Metabolites ENSG00000178573 ENSG00000100387 ENSG00000079999 PMC3083967__F5 Key regulators of the mammalian target of rapamycin signaling pathway ENSG00000198793 ENSG00000118515 ENSG00000164327 PMC8575759__F7 Microglia Activation in Retinal Ischemia Triggers Cytokine and Toll-Like Receptor Response ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC8282711__F1 One Carbon Metabolism and Early Development: A Diet-Dependent Destiny ENSG00000284320 ENSG00000228716 ENSG00000065911 ENSG00000100714 ENSG00000173599 ENSG00000124275 ENSG00000116761 ENSG00000016391 ENSG00000116984 ENSG00000133027 PMC8959714__F2 Understanding the Role of SARS-CoV-2 ORF3a in Viral Pathogenesis and COVID-19 ENSG00000140564 ENSG00000130234 ENSG00000184012 PMC118037__F6 Model depicting direct and indirect regulation of clock output genes involved in conidiation PMC3504253__F2 Activated Wnt pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9348619__F6 Differentially Active and Conserved Neural Enhancers Define Two Forms of Adaptive Noncoding Evolution in Humans ENSG00000087095 ENSG00000189319 ENSG00000101109 ENSG00000162490 ENSG00000134982 ENSG00000104517 ENSG00000124766 ENSG00000168036 ENSG00000100744 ENSG00000196470 ENSG00000234616 ENSG00000175029 ENSG00000135341 ENSG00000136826 ENSG00000106829 ENSG00000171016 ENSG00000107263 ENSG00000101849 ENSG00000147869 ENSG00000113558 ENSG00000136997 ENSG00000285438 ENSG00000186174 ENSG00000215301 PMC8773419__F1 DNA Methylation: A Promising Approach in Management of Alzheimer’s Disease and Other Neurodegenerative Disorders ENSG00000088305 ENSG00000139372 PMC4523609__F9 Upstream negative regulators of the Hippo pathway ENSG00000291971 ENSG00000198670 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC7277648__F1 Anti-aging mechanisms of metformin: From metabolic controller of longevity to the sentinel of epigenetic information ENSG00000147162 ENSG00000198408 ENSG00000198793 ENSG00000096717 PMC7986977__F5 Metabolic pathway associations of significantly different metabolites in COVID-19 ENSG00000139287 ENSG00000129167 ENSG00000188676 PMC11998454__F4 Exosomes secreted by BMSCs, modified with HO-1, deliver miR-124-3p ENSG00000167468 ENSG00000115107 PMC7705115__F4 Crosstalk between JAK2-STAT5 and hormone receptors, growth factors, inflammatory cytokines, and integrins ENSG00000178568 PMC1774725__F1 Tumour necrosis factor related apoptosis inducing ligand (TRAIL) receptor signalling ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC8197327__F1 Emerging Roles for Browning of White Adipose Tissue in Prostate Cancer Malignant Behaviour ENSG00000107562 ENSG00000171791 ENSG00000175104 ENSG00000121966 PMC7705115__F1 Novel components of the JAK2-STAT5 signaling pathway ENSG00000120833 ENSG00000138161 PMC3356660__F1 A model summarizing the results of the study in which the miR-301a molecule inhibits the PIAS3 enzyme, resulting in the promotion of the IL-6/23 receptor–STAT3 pathway and stimulation of Th17 differentiation ENSG00000162594 ENSG00000168610 PMC7705115__F3 Crosstalk between the PI3K/Akt and JAK2-STAT5 signaling pathways ENSG00000087842 ENSG00000140443 PMC8832510__F2 Forkhead Box Family in Bone Metabolism and Diseases ENSG00000182718 ENSG00000178860 ENSG00000164379 ENSG00000291971 ENSG00000120149 ENSG00000187140 ENSG00000168036 ENSG00000103241 ENSG00000170365 ENSG00000176692 ENSG00000128272 ENSG00000150907 ENSG00000175104 PMC7912673__F1 Panel (A): Mechanisms of drug inhibition on cellular pathways PMC5766647__F3 Regulatory T cells are controlled by epigenetic mechanisms and T cell receptor (TCR) and interleukin-2 (IL-2) pathway ENSG00000198793 ENSG00000049768 PMC5626664__F4 Tobacco-specific carcinogens induce hypermethylation, DNA adducts and DNA damage in Bladder Cancer ENSG00000141086 ENSG00000170558 ENSG00000203710 PMC4446786__F1 Intracellular mechanisms activated by leucine ENSG00000169047 ENSG00000155792 ENSG00000167965 ENSG00000103257 PMC2943488__F1 Schematic of the drug- and cytokine-induced hepatocellular death signaling network, curated from literature references-, - ENSG00000132906 ENSG00000002330 ENSG00000102871 ENSG00000138794 ENSG00000198793 ENSG00000169047 ENSG00000132478 ENSG00000168040 ENSG00000127191 ENSG00000168610 ENSG00000164305 ENSG00000105397 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC5253631__F8 Exome and genome sequencing of nasopharynx cancer identifies NFKB pathway activating mutations ENSG00000224320 ENSG00000100906 ENSG00000198793 ENSG00000263528 ENSG00000131323 ENSG00000083799 ENSG00000121879 ENSG00000175104 ENSG00000196712 ENSG00000109670 PMC3025434__F1 Simplified overview of the pathways involved in miRNA regulation of gene expression in addiction ENSG00000138378 ENSG00000198793 ENSG00000168758 ENSG00000132326 ENSG00000117152 ENSG00000118257 ENSG00000113360 ENSG00000123908 PMC3762715__F5 Transcriptome Profiling Reveals Th17-Like Immune Responses Induced in Zebrafish Bath-Vaccinated with a Live Attenuated Vibrio anguillarum ENSG00000134982 ENSG00000177606 ENSG00000168036 PMC6781988__F8 Proposed mechanism of miR-125a-5p function in HCC ENSG00000196396 ENSG00000173327 PMC9581121__F1 Amino acid metabolism in primary bone sarcomas ENSG00000284320 ENSG00000228716 ENSG00000135423 ENSG00000092621 ENSG00000135069 ENSG00000146733 ENSG00000070669 PMC3027158__F7 Biological network of genes linked to the canonical pathway "molecular mechanisms of cancer" that were hypomethylated (fold change >1.5) in zebrafish hepatocellular carcinoma compared to healthy liver ENSG00000149311 ENSG00000002330 ENSG00000134982 ENSG00000196549 ENSG00000177606 ENSG00000166278 ENSG00000080839 ENSG00000196712 PMC8833225__F4 Cathepsin family target genes in phagosomes ENSG00000003056 ENSG00000135218 ENSG00000170458 ENSG00000168818 ENSG00000115020 ENSG00000079950 ENSG00000136869 ENSG00000005381 ENSG00000274145 PMC2610122__F1 Classical view of three independent Wnt signalling pathways ENSG00000087095 ENSG00000169071 ENSG00000134982 PMC3027158__F8 Ingenuity network predicted for genes that were both hypomethylated and increased in expression in zebrafish HCC (shaded red) ENSG00000181163 PMC7716795__F1 Host genetics and infectious disease: new tools, insights and translational opportunities ENSG00000174125 ENSG00000064490 ENSG00000143390 ENSG00000213928 ENSG00000138600 ENSG00000232326 ENSG00000027697 ENSG00000150455 ENSG00000276561 ENSG00000142166 ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000121060 ENSG00000285379 ENSG00000184216 ENSG00000133111 PMC9019694__F2 Apoptosis, autophagy and ferroptosis by non-coding RNAs in metastatic non-small cell lung cancer (Review) ENSG00000118263 ENSG00000170558 ENSG00000058091 ENSG00000127528 ENSG00000181467 ENSG00000150457 ENSG00000145386 ENSG00000118971 ENSG00000168610 ENSG00000089159 ENSG00000130164 ENSG00000125398 ENSG00000135446 ENSG00000048052 ENSG00000146648 PMC9019694__F5 Apoptosis, autophagy and ferroptosis by non-coding RNAs in metastatic non-small cell lung cancer (Review) ENSG00000188486 ENSG00000004975 ENSG00000011566 ENSG00000198793 ENSG00000144848 ENSG00000164190 ENSG00000156171 ENSG00000143155 PMC12018836__F4 Illustration of eATP signal transduction ENSG00000122882 ENSG00000110921 ENSG00000136997 PMC6137108__F3 Enriched KEGG dopaminergic synapse pathway following perinatal nicotine exposure in DA neurons ENSG00000215568 ENSG00000027075 ENSG00000172380 ENSG00000163064 ENSG00000178363 ENSG00000176533 ENSG00000127588 ENSG00000149295 ENSG00000186469 ENSG00000129007 PMC3641182__F2 Humanin: a harbinger of mitochondrial-derived peptides? ENSG00000122756 ENSG00000168610 PMC11278003__F5 KEGGs pathway and GO molecular function (MF) analysis based on AD correlated interactors of Apaf-1 and TNFA ENSG00000125538 ENSG00000136869 ENSG00000132693 PMC6137108__F4 Enriched KEGG neurotrophin signaling network following perinatal nicotine exposure in DA neurons ENSG00000002330 ENSG00000115904 ENSG00000141639 ENSG00000173039 ENSG00000099942 ENSG00000078900 ENSG00000148082 ENSG00000175467 ENSG00000167941 ENSG00000177606 ENSG00000134243 ENSG00000090376 ENSG00000145349 PMC5297631__F1 Inflammatory role of phagocyte apoptotic pathways in rheumatic diseases ENSG00000120868 ENSG00000168040 PMC6667250__F3 Feed efficiency and the autophagy pathway ENSG00000197769 ENSG00000177169 ENSG00000152348 ENSG00000188554 ENSG00000198382 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000171791 ENSG00000145782 ENSG00000057663 ENSG00000133027 PMC6548002__F5 Signaling pathway based on the literatures we reviewed ENSG00000105894 ENSG00000157368 ENSG00000187957 ENSG00000291971 ENSG00000136997 ENSG00000168036 ENSG00000178568 PMC1682017__F5 Effect of HRG stimulation versus EGF stimulation in high HER2-expressing cells ENSG00000113905 ENSG00000291971 ENSG00000138798 PMC8469440__F3 Kynurenine Pathway—New Linkage between Innate and Adaptive Immunity in Autoimmune Endocrinopathies ENSG00000134982 ENSG00000198793 ENSG00000106546 PMC7564545__F2 Interplay between innate immunity and hepatitis E virus (HEV) ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000187608 ENSG00000105397 ENSG00000115415 ENSG00000185745 ENSG00000276561 ENSG00000164342 PMC9056228__F2 Research Progress of Ferroptosis in Adiposity-Based Chronic Disease (ABCD) ENSG00000228716 ENSG00000167468 ENSG00000197429 ENSG00000102967 PMC5609334__F1 NF-kB pathway ENSG00000135960 ENSG00000186716 ENSG00000026103 PMC8469440__F1 Kynurenine Pathway—New Linkage between Innate and Adaptive Immunity in Autoimmune Endocrinopathies ENSG00000188676 PMC2203613__F10 Functional interacteome of all parietal cortex proteins ENSG00000142192 ENSG00000277586 ENSG00000105329 ENSG00000050628 ENSG00000138798 ENSG00000115263 ENSG00000177606 ENSG00000073756 ENSG00000065243 PMC11281655__F2 RIG-I-like receptor signaling pathway in antiviral immunity ENSG00000141867 ENSG00000183735 ENSG00000088888 ENSG00000276561 PMC9653755__F2 Current Status and Prospects of Targeted Therapy for Osteosarcoma ENSG00000178999 ENSG00000198793 ENSG00000087586 PMC6026538__F2 Roles of the Mevalonate Pathway and Cholesterol Trafficking in Pulmonary Host Defense ENSG00000162711 ENSG00000150782 ENSG00000135218 ENSG00000136869 ENSG00000160179 PMC8588809__F2 Effect of chronic ethanol consumption in rhesus macaques on the nucleus accumbens core transcriptome ENSG00000177169 ENSG00000163435 ENSG00000171105 ENSG00000163914 ENSG00000173599 PMC8777795__F3 Novel Pathway of Flavonoids Protecting against Inflammatory Bowel Disease: Modulating Enteroendocrine System ENSG00000197635 PMC4543455__F5 Canonical Wnt pathway ENSG00000134982 ENSG00000166402 ENSG00000124253 PMC6305104__F3 MicroRNA-messenger RNA interactions involving JAK-STAT signaling genes in colorectal cancer ENSG00000090534 ENSG00000127948 PMC6305104__F2 MicroRNA-messenger RNA interactions involving JAK-STAT signaling genes in colorectal cancer ENSG00000120833 ENSG00000213928 ENSG00000005339 ENSG00000114737 ENSG00000198793 ENSG00000115904 ENSG00000137193 ENSG00000105647 ENSG00000131095 ENSG00000171791 ENSG00000138356 ENSG00000138378 ENSG00000117020 ENSG00000115415 ENSG00000136997 ENSG00000022267 ENSG00000115145 PMC7903498__F1 Effect of Melatonin Modulation of Non-coding RNAs on Central Nervous System Disorders: An Updated Review ENSG00000096717 PMC4105970__F5 Schematic model of specific KDAC targeting through pharmaco-logic modulation of its regulatory pathway ENSG00000196591 ENSG00000185591 ENSG00000107874 PMC8192756__F10 Taurine ameliorates thioacetamide induced liver fibrosis in rats via modulation of toll like receptor 4/nuclear factor kappa B signaling pathway ENSG00000170458 ENSG00000172936 ENSG00000175104 PMC9570387__F3 Phosphorylation Signals Downstream of Dopamine Receptors in Emotional Behaviors: Association with Preference and Avoidance PMC9691176__F1 Vascular Endothelial Growth Factor Receptor 2: Molecular Mechanism and Therapeutic Potential in Preeclampsia Comorbidity with Human Immunodeficiency Virus and Severe Acute Respiratory Syndrome Coronavirus 2 Infections ENSG00000070831 ENSG00000112715 ENSG00000150630 PMC6905088__F8 Relative P450 involvement in N-dealkylation pathways of terbinafine ENSG00000138115 ENSG00000165841 ENSG00000197408 ENSG00000140505 PMC2224586__F3 HCMV regulates the expression of multiple components of the NFKB signaling pathway (see Table and Table S1 in the supplemental material for abbreviations) ENSG00000104856 ENSG00000226275 ENSG00000138798 ENSG00000173039 ENSG00000150455 PMC7297305__F4 LncRNA-miRNA-mRNA network for human primed, naive and extended pluripotent stem cells ENSG00000163235 ENSG00000111186 PMC6982094__F3 Exogenous GM3 and the EGFR-mediated PI3K/AKT signal pathway ENSG00000069482 ENSG00000138798 ENSG00000198793 ENSG00000111224 PMC6905088__F4 Metabolic model predictions for P450 catalyzed N-dealkylations ENSG00000138115 ENSG00000165841 ENSG00000197408 ENSG00000140505 ENSG00000130649 ENSG00000255974 PMC3064843__F5 DNA Repair Deficiency and Neurological Disease ENSG00000105486 ENSG00000136936 PMC8195768__F2 Manifold role of ubiquitin in Helicobacter pylori infection and gastric cancer ENSG00000070831 ENSG00000145365 ENSG00000168036 PMC3227781__F2 Genomic and nongenomic vascular effects of estrogen ENSG00000291971 ENSG00000145321 PMC4936004__F4 LumA-R2 samples overexpress genes in the T cell receptor signaling pathway ENSG00000110395 ENSG00000213658 ENSG00000117091 ENSG00000010810 ENSG00000163599 ENSG00000113263 PMC3068924__F4 CAERUS: Predicting CAncER oUtcomeS Using Relationship between Protein Structural Information, Protein Networks, Gene Expression Data, and Mutation Data ENSG00000157764 ENSG00000134982 ENSG00000167941 ENSG00000155926 ENSG00000006451 ENSG00000163914 ENSG00000173599 ENSG00000177606 ENSG00000072274 ENSG00000123374 ENSG00000119912 PMC5181566__F3 Two sets of peripheral proteins (blue and red) with the same core proteins (green) are shown ENSG00000012048 ENSG00000005339 ENSG00000177606 ENSG00000120693 ENSG00000173039 ENSG00000185591 ENSG00000168610 ENSG00000139687 PMC8564637__F7 MeCP2 drives hepatocellular carcinoma progression via enforcing HOXD3 promoter methylation and expression through the HB‐EGF/EGFR pathway ENSG00000113070 ENSG00000128652 ENSG00000146648 PMC7783757__F7 Interrelation between 4 target metabolites and 4 concurrently mutated genes ENSG00000029363 ENSG00000110721 ENSG00000076003 ENSG00000111737 ENSG00000136807 ENSG00000182247 ENSG00000116670 ENSG00000158786 ENSG00000276870 ENSG00000197943 ENSG00000092067 ENSG00000196498 ENSG00000179348 ENSG00000139687 ENSG00000065357 ENSG00000120693 ENSG00000149091 ENSG00000101811 ENSG00000076053 ENSG00000106459 ENSG00000120063 ENSG00000175899 ENSG00000066136 ENSG00000172296 ENSG00000146648 ENSG00000133027 ENSG00000033327 ENSG00000070831 ENSG00000001167 ENSG00000077044 ENSG00000087085 ENSG00000049618 ENSG00000129219 ENSG00000105894 ENSG00000117713 ENSG00000006194 ENSG00000136267 ENSG00000129214 ENSG00000142599 ENSG00000108788 ENSG00000124181 ENSG00000089199 ENSG00000146376 ENSG00000005339 ENSG00000103066 ENSG00000132305 ENSG00000096996 ENSG00000085872 ENSG00000168066 ENSG00000100596 ENSG00000186716 ENSG00000177606 ENSG00000102974 PMC8996108__F7 Blueberry Juice Attenuates Pulmonary Fibrosis via Blocking the TGFB1/Smad Signaling Pathway ENSG00000197299 ENSG00000168610 PMC8100510__F1 Notch, Hedgehog, and Wnt Signaling Pathways in the Resistance of Tumors to Anticancer Therapies ENSG00000106571 ENSG00000134982 ENSG00000168036 ENSG00000128602 PMC3099707__F10 Dual MC4R signaling model to account for “rescue” of Ay phenotype by alterations in MC4R trafficking ENSG00000102858 ENSG00000074319 ENSG00000166603 PMC4333206__F1 Notch receptors (Notch1-4) and ligands (DLL1, 3 and 4, Jagged 1-2) are expressed in tumor, normal, and endothelial cells ENSG00000128917 ENSG00000168036 ENSG00000123374 PMC2715810__F7 Model of PERK pathway controlling rRNA transcription and translation in comparison to mTOR ENSG00000278494 ENSG00000101751 ENSG00000144895 ENSG00000198793 PMC2854204__F1 TOR-dependent control of autophagy: biting the hand that feeds PMC4042557__F4 Graphical overview of the Canonical Pathway analysis ENSG00000291971 PMC5727168__F7 Hypoxia/IL-6/lncTCF7/TCF7/Wnt signalling axis in glioma ENSG00000168610 PMC6019481__F9 Regulation of the synaptic vesicle cycle pathway by SE in OVX with (CES)/without (COS) E2-replacement with respect to their non-SE counterparts (CEN and CON) ENSG00000091664 ENSG00000136854 ENSG00000161203 ENSG00000042753 ENSG00000105402 ENSG00000104888 ENSG00000132639 ENSG00000067715 ENSG00000168993 ENSG00000148408 ENSG00000130477 ENSG00000183020 ENSG00000220205 PMC4259419__F2 AXL kinase as a novel target for cancer therapy ENSG00000167601 ENSG00000146648 PMC9668530__F2 Recent advances in understanding the metabolic plasticity of ovarian cancer: A systematic review ENSG00000175567 PMC9902738__F2 Potential benefits of cinnamon to patients with diabetes, obesity, or CVDs ENSG00000104321 ENSG00000135218 PMC5570638__F1 Mammalian target of rapamycin pathway PMC4148087__F7 Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention ENSG00000149311 ENSG00000012048 ENSG00000139618 PMC4148087__F6 Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention ENSG00000123999 ENSG00000177169 ENSG00000291971 ENSG00000121879 ENSG00000146648 PMC4148087__F5 Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention ENSG00000198793 ENSG00000168036 PMC5821844__F7 Differentially expressed artemisinin and other terpenoid biosynthetic pathway genes of A ENSG00000110921 ENSG00000115008 ENSG00000197429 PMC4148087__F4 Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention ENSG00000140443 PMC10131518__F2 Primary and Secondary micro-RNA Modulation the Extrinsic Pathway of Apoptosis in Hepatocellular Carcinoma ENSG00000104689 ENSG00000108691 ENSG00000105329 ENSG00000163629 ENSG00000078747 ENSG00000177606 ENSG00000026508 ENSG00000171791 ENSG00000112715 ENSG00000168610 PMC4148087__F3 Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention ENSG00000272398 ENSG00000026508 ENSG00000079432 ENSG00000140443 PMC2759177__F3 Survival signals generated by PI3K and PLD that target mTOR ENSG00000002330 PMC4148087__F2 Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention ENSG00000157404 ENSG00000120875 ENSG00000134853 ENSG00000168036 ENSG00000040199 ENSG00000123374 ENSG00000196712 PMC7210543__F3 Scribble complex in immune cells ENSG00000291603 ENSG00000111537 ENSG00000070831 ENSG00000109943 PMC9321239__F7 Altered RNome expression in Murine Gastrocnemius Muscle following Exposure to Jararhagin, a Metalloproteinase from Bothrops jararaca Venom ENSG00000087095 ENSG00000142192 ENSG00000101474 ENSG00000170458 ENSG00000102871 ENSG00000138798 ENSG00000130159 ENSG00000127191 ENSG00000026103 PMC7215568__F2 Action of MNKs ENSG00000136158 ENSG00000167772 ENSG00000198793 ENSG00000156574 ENSG00000155792 ENSG00000168036 ENSG00000123374 PMC7982081__F5 Angiocrine factors control liver function ENSG00000138755 ENSG00000118520 ENSG00000168646 ENSG00000276799 ENSG00000146374 PMC5548098__F1 The major pathways of Cu distribution in human cells ENSG00000173992 ENSG00000138495 ENSG00000123191 ENSG00000177556 PMC5964132__F4 Multiple signaling pathways are upregulated in MCF7 parathyroid hormone-related protein-overexpressing cells ENSG00000155966 ENSG00000152684 ENSG00000148803 ENSG00000109321 ENSG00000124882 ENSG00000164619 PMC5332279__F5 Schematic model of the TRIM8‐PIAS3‐STAT3 pathway that regulates glioblastoma stemness ENSG00000171206 ENSG00000168610 PMC11673418__F1 Simplified schematic representation of the PI3K/AKT/mTOR, RAS/RAF/MAPK, RB, and p53 pathways ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000139687 ENSG00000198625 PMC9250260__F3 p63 regulated pathway in cancer ENSG00000134982 ENSG00000140464 PMC8625071__F1 Natural Products for Pancreatic Cancer Treatment: From Traditional Medicine to Modern Drug Discovery ENSG00000198793 ENSG00000015285 ENSG00000168610 PMC5449640__F5 Hypothetical driver pathways for BRCA carcinogenesis and progression ENSG00000095015 ENSG00000065559 ENSG00000168036 ENSG00000121879 ENSG00000139618 ENSG00000117713 ENSG00000149311 ENSG00000066468 ENSG00000107485 ENSG00000198670 ENSG00000051180 ENSG00000120235 ENSG00000064012 ENSG00000196712 ENSG00000026103 PMC5449640__F4 Known KEGG pathway knowledge in cancer ENSG00000066468 ENSG00000095015 ENSG00000065559 ENSG00000198670 ENSG00000121879 PMC7532371__F5 Red nodes are genes of CMTgset, and the green nodes are nonoriginal/extended genes ENSG00000163399 ENSG00000103266 ENSG00000101367 ENSG00000100285 ENSG00000179222 ENSG00000087053 ENSG00000170606 ENSG00000181409 ENSG00000186889 ENSG00000151466 ENSG00000133812 ENSG00000152137 ENSG00000063601 ENSG00000166847 ENSG00000146648 ENSG00000100603 PMC7532371__F4 Biological process crosstalk among CMTgset-enriched biological processes ENSG00000115718 PMC5902451__F3 Downstream interactors affected by deleterious SAPs in CTNNB1 and KRAS ENSG00000017797 ENSG00000138795 ENSG00000178585 ENSG00000070831 ENSG00000292149 ENSG00000134982 ENSG00000170558 ENSG00000115266 ENSG00000173482 ENSG00000168036 ENSG00000168646 ENSG00000108061 PMC6435474__F4 Functional annotation of extensively and divergently expressed miRNAs in suprachiasmatic nucleus of ClockΔ19 mutant mice ENSG00000105329 ENSG00000170027 ENSG00000134982 ENSG00000105568 ENSG00000118971 ENSG00000131023 ENSG00000156475 ENSG00000089685 ENSG00000136997 ENSG00000115266 ENSG00000132326 ENSG00000179094 ENSG00000204217 PMC9461657__F4 Autophagy-related Proteins in Genome Stability: Autophagy-Dependent and Independent Actions ENSG00000149311 ENSG00000177169 ENSG00000183735 ENSG00000198793 ENSG00000158828 ENSG00000105810 ENSG00000166851 ENSG00000276876 PMC9367281__F4 PTEN in Epithelial–Mesenchymal Transition ENSG00000291971 PMC6232459__F7 HBSP regulation on PI3K/Akt signaling to affect Fas-apoptotic pathway ENSG00000140992 ENSG00000168040 ENSG00000026103 PMC7551260__F2 Antiviral immune response and evasion mechanism of coronaviruses ENSG00000197635 ENSG00000185436 ENSG00000125347 ENSG00000276561 ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000130234 ENSG00000184012 ENSG00000102007 ENSG00000243646 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC2652310__F1 Anaerobic metabolic pathways in C ENSG00000146701 PMC11673418__F7 Wnt/Beta-Catenin Pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11673418__F9 TGFB signaling pathway in gene expression regulation PMC9367281__F1 PTEN in Epithelial–Mesenchymal Transition PMC5777710__F13 CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NFKB/ iNOS pathway in STZ-induced diabetic mice ENSG00000086991 ENSG00000123374 PMC6121636__F1 HO-1 dependent pathway activated in neurons and in the different glial cells ENSG00000156273 PMC10926848__F4 BCR signaling pathway and BCR-associated CXCR4 signaling in CLL ENSG00000177455 ENSG00000107562 ENSG00000186716 ENSG00000197943 ENSG00000121966 PMC4187706__F9 Schematic model showing AngII regulation of HSD3B1 in H295R cells ENSG00000203859 ENSG00000179142 ENSG00000203857 PMC8855721__F7 Potential mechanism of the effects of HF-MSCs in the treatment of LC PMC11074996__F1 The multi-modular engineering and efflux strategies for lycopene synthesis in Saccharomyces cerevisiae ENSG00000157554 ENSG00000067064 ENSG00000197429 PMC5146274__F8 Outside-in integrin signalling regulates haematopoietic stem cell function via Periostin-Itgav axis ENSG00000259207 ENSG00000133110 PMC12145652__F7 GETV Nsp2 inhibiting the RLR signalling pathway by regulating IRF3 activation ENSG00000183735 ENSG00000088888 ENSG00000102753 ENSG00000186432 ENSG00000107201 PMC6127653__F2 Role of p21-activated kinases in Kras-driven oncogenic signalling pathways ENSG00000070831 ENSG00000148926 PMC3903702__F1 EZH2 takes the stage when BRCA1 loses ENSG00000012048 ENSG00000151376 ENSG00000074266 ENSG00000178691 PMC140507__F1 The PI 3-kinase pathway by RNAi PMC6399846__F2 KIT mutant GISTs have enrichment for KEGG cell cycle pathway (p = 0.0007) and spliceosome pathway (p = 0.0008) using STRING v10 clustering of significantly somatic mutated genes (p < 0.003) ENSG00000157404 ENSG00000070814 ENSG00000002746 ENSG00000063244 ENSG00000147274 ENSG00000136206 ENSG00000283630 ENSG00000135960 ENSG00000175718 ENSG00000113318 ENSG00000291836 ENSG00000013441 ENSG00000129646 ENSG00000177606 ENSG00000004897 ENSG00000139687 ENSG00000116661 PMC8019700__F2 Human rhinoviruse (HRV) replication and inflammatory response ENSG00000130164 ENSG00000128536 PMC4747800__F1 PI3K/AKT/mTOR pathway and cellular processes controlled by downstream signaling ENSG00000002330 ENSG00000081913 ENSG00000150907 ENSG00000198793 ENSG00000164327 ENSG00000040199 PMC7077606__F1 SFRP5 at the crossroad between obesity, T2DM and CHD ENSG00000169071 ENSG00000120057 ENSG00000163914 PMC8158769__F1 Targeting the Complement Cascade in the Pathophysiology of COVID-19 Disease ENSG00000244731 ENSG00000166278 PMC9898571__F7 Osteoarthritis: pathogenic signaling pathways and therapeutic targets ENSG00000170365 PMC12058719__F2 Osteoporosis (OP) regulation by protein arginine methyltransferases (PRMTs) (A)PRMT1 influences bone formation and resorption through the BMP2/Smad and other pathways, thereby mitigating OP ENSG00000178860 ENSG00000169245 ENSG00000170365 ENSG00000162733 ENSG00000134321 ENSG00000120693 ENSG00000126457 ENSG00000132600 ENSG00000163132 ENSG00000198890 ENSG00000175104 ENSG00000082212 PMC9898571__F3 Osteoarthritis: pathogenic signaling pathways and therapeutic targets ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC9898571__F6 Osteoarthritis: pathogenic signaling pathways and therapeutic targets ENSG00000154736 ENSG00000168036 ENSG00000112715 ENSG00000168610 ENSG00000158859 PMC9327256__F7 Pretreatment of nucleus pulposus mesenchymal stem cells with appropriate concentration of H2O2 enhances their ability to treat intervertebral disc degeneration ENSG00000150457 ENSG00000131023 PMC6186824__F2 BAFFR-induced intracellular signaling ENSG00000177455 ENSG00000145604 ENSG00000095585 ENSG00000104856 ENSG00000186716 ENSG00000198793 ENSG00000197943 ENSG00000131323 ENSG00000127191 ENSG00000010671 PMC8535999__F1 Receptor-Loaded Virion Endangers GPCR Signaling: Mechanistic Exploration of SARS-CoV-2 Infections and Pharmacological Implications ENSG00000130234 ENSG00000072415 PMC5094909__F1 Energy Metabolism and Inflammation in Brain Aging and Alzheimer’s Disease PMC5964014__F7 Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury ENSG00000177606 PMC7971856__F7 Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol ENSG00000164430 ENSG00000088888 ENSG00000136869 PMC8387591__F1 Mouse Models of Germinal Center Derived B-Cell Lymphomas ENSG00000120063 ENSG00000112576 ENSG00000005339 ENSG00000007312 ENSG00000150907 ENSG00000136997 ENSG00000213999 ENSG00000172936 ENSG00000171791 ENSG00000273936 ENSG00000026103 PMC8834116__F7 Niclosamide Ethanolamine Salt Alleviates Idiopathic Pulmonary Fibrosis by Modulating the PI3K-mTORC1 Pathway ENSG00000108821 PMC7485387__F3 FGF23 signaling in the kidney ENSG00000111012 ENSG00000118972 ENSG00000019186 ENSG00000274348 ENSG00000077782 PMC6705128__F2 DUBs regulating TCR signaling ENSG00000184979 ENSG00000135655 ENSG00000264522 ENSG00000291603 ENSG00000213658 ENSG00000083799 PMC5449757__F1 Schematic depiction of uPAR/suPARAvB3 integrin signaling at the glomerular filtration level in health and diabetic disease PMC7485387__F1 FGF23 regulation in osteocytes ENSG00000118972 ENSG00000152266 ENSG00000293604 ENSG00000150907 ENSG00000125538 ENSG00000152592 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000077782 ENSG00000168610 ENSG00000140443 PMC5725996__F1 Summary diagram of energy metabolism pathway ENSG00000160194 ENSG00000262785 ENSG00000139180 ENSG00000067057 ENSG00000130414 ENSG00000173599 ENSG00000105929 ENSG00000107902 ENSG00000105953 ENSG00000166816 ENSG00000124253 ENSG00000062485 PMC2997002__F2 Gene list involved in TLR pathway generated by KEGG ENSG00000136997 PMC2997002__F3 MAPK signaling pathways generated by GenMAPP ENSG00000027075 ENSG00000157764 ENSG00000170458 ENSG00000130522 ENSG00000269335 ENSG00000100485 ENSG00000132341 PMC5858821__F1 Illustration of self-assembly and accumulation of redox-sensitive PTX-HSV nanoparticles in tumor tissues and their intracellular trafficking pathway ENSG00000026508 ENSG00000188158 PMC3792586__F1 TNF signalling pathway ENSG00000110514 ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC7881277__F1 Deregulated MicroRNAs in Age-Related Macular Degeneration Pathology ENSG00000132906 ENSG00000063176 ENSG00000002330 PMC8446557__F3 EGFR‐mutated stage IV non‐small cell lung cancer: What is the role of radiotherapy combined with TKI? ENSG00000149311 ENSG00000012048 ENSG00000065361 ENSG00000132646 ENSG00000168036 ENSG00000051180 PMC7710791__F2 Pathway 1—management of a previously healthy child/adolescent, suspected, or probable case of COVID-19 ENSG00000090402 ENSG00000157766 ENSG00000127948 PMC7881277__F3 Apoptosis signaling pathway and the predicted gene targets of miR-410 (IL1R, XIAP, NTRK1, PPP3CA, PRKACB3) and miR-19a (IL1R1, PIK3R3, MAP3K14, PRKACB3), which are involved in cytokine–cytokine receptor interaction ENSG00000149311 ENSG00000002330 ENSG00000102871 ENSG00000172936 ENSG00000168040 ENSG00000026103 PMC7530066__F9 Insulin-like growth factor 1-Receptor signaling stimulates GRP78 expression through the PI3K/AKT/mTOR/ATF4 axis ENSG00000128272 ENSG00000198793 ENSG00000140443 PMC7881277__F2 Deregulated MicroRNAs in Age-Related Macular Degeneration Pathology ENSG00000039537 ENSG00000003436 ENSG00000113600 ENSG00000110799 ENSG00000181104 ENSG00000244731 ENSG00000088926 ENSG00000166278 ENSG00000115718 ENSG00000122194 ENSG00000178726 ENSG00000117322 ENSG00000185010 ENSG00000104368 ENSG00000180210 ENSG00000126218 ENSG00000101981 ENSG00000117525 ENSG00000011422 ENSG00000057593 ENSG00000175899 ENSG00000080618 ENSG00000198734 ENSG00000164344 PMC5979464__F3 Beta2-adrenergic receptor signal transduction ENSG00000288263 PMC7881277__F4 Neurodegenerative disorders signaling pathway and the predicted gene targets of miR-19a (SOD1) and miR-126, which are involved in the insulin signaling pathway ENSG00000142192 ENSG00000002330 ENSG00000005339 ENSG00000100285 ENSG00000138794 ENSG00000158828 ENSG00000105290 ENSG00000131095 ENSG00000171791 ENSG00000164305 ENSG00000064300 ENSG00000107282 ENSG00000064012 PMC7816079__F5 Saponin biosynthetic pathway in P. notoginseng and expression profiles of key enzyme genes.The genes in the green box are the UGT genes identified in this study ENSG00000110921 ENSG00000152904 ENSG00000197429 ENSG00000151914 ENSG00000167508 ENSG00000157005 PMC5979464__F1 The major neuroendocrine and autonomic pathways that regulate secondary immune organs are illustrated PMC6817488__F5 AA-induced vasorelaxation and relationship to aldehyde metabolism ENSG00000145321 PMC5979464__F4 Canonical B2-adrenergic receptor (B2-AR) signaling response, the anti-inflammatory cytokine profile mediated by protein kinase A (PKA), and the major anti-inflammatory cellular mediators of the resulting anti-inflammatory immune response ENSG00000288263 PMC10941343__F12 Elucidating the anti-hypertensive mechanisms of Uncaria rhynchophylla-Alisma plantago-aquatica L: an integrated network pharmacology, cluster analysis, and molecular docking approach ENSG00000291971 ENSG00000138798 ENSG00000168036 ENSG00000162692 ENSG00000146648 PMC2674225__F2 Repression of TGFB-RII and abrogated signaling through the Smad pathway ENSG00000111537 ENSG00000115415 ENSG00000138798 PMC7479443__F1 De novo purine synthesis pathway ENSG00000128050 ENSG00000198931 PMC8283767__F2 Non-coding RNAs in Alzheimer’s Disease: From Regulated Mechanism to Therapeutic Targets and Diagnostic Biomarkers ENSG00000142192 ENSG00000070950 ENSG00000146648 PMC8584118__F3 Nod-like Receptors: Critical Intracellular Sensors for Host Protection and Cell Death in Microbial and Parasitic Infections ENSG00000278718 ENSG00000162711 ENSG00000167207 ENSG00000109606 ENSG00000174885 ENSG00000091592 ENSG00000091106 ENSG00000106100 ENSG00000150782 ENSG00000125538 ENSG00000160703 ENSG00000142405 ENSG00000164342 PMC3254618__F3 Identification of Gene Networks and Pathways Associated with Guillain-Barré Syndrome ENSG00000002330 PMC6884345__F3 TGFB signaling in the colonic mucosa PMC4411486__F3 Predicted co-regulation of genes in the MAPK signaling pathway targeted by downregulated miRNAs in BAT during torpor ENSG00000170458 PMC6122627__F5 The pathways being affected by MDD and by treatments ENSG00000172936 ENSG00000158050 ENSG00000079999 PMC4411486__F2 Predicted co-regulation of genes in the MAPK signaling pathway targeted by the downregulated miRNAs in WAT during torpor ENSG00000172680 ENSG00000151657 ENSG00000170458 ENSG00000177606 ENSG00000026103 PMC4411486__F4 Predicted co-regulation of genes in the TGFB signaling pathway targeted by upregulated miRNAs in WAT during torpor ENSG00000111537 ENSG00000113558 ENSG00000156574 PMC6071023__F2 Resistance to EGFR tyrosine kinase inhibitors ENSG00000141448 ENSG00000188064 ENSG00000138798 ENSG00000198793 ENSG00000128602 ENSG00000146648 PMC7105297__F1 Genome-wide CRISPR/Cas9 screen for positive regulators of SL biosynthesis ENSG00000115091 ENSG00000134851 ENSG00000241553 ENSG00000138071 ENSG00000061676 ENSG00000106546 ENSG00000143418 ENSG00000111229 ENSG00000113384 ENSG00000100596 ENSG00000165389 ENSG00000119537 ENSG00000148154 PMC5867104__F2 Wnt/beta‐catenin pathway‐related lncRNAs and their interactions in cancers ENSG00000165119 ENSG00000168036 ENSG00000177283 PMC5867104__F1 Wnt/B‐catenin signalling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8946235__F1 Targeting the DNA Damage Response Pathway as a Novel Therapeutic Strategy in Colorectal Cancer ENSG00000143799 ENSG00000012061 ENSG00000012048 ENSG00000083093 ENSG00000132646 ENSG00000051180 ENSG00000095002 ENSG00000138385 ENSG00000122512 ENSG00000139618 PMC12111560__F5 Expression profile of candidate genes involved in the organic acid metabolic pathway in pomegranate ENSG00000065833 ENSG00000062485 PMC8048608__F3 UPR pathway highlighting gene‐expression differences between the low‐risk and high‐risk PSC clusters ENSG00000128272 ENSG00000144895 ENSG00000159461 ENSG00000165280 ENSG00000127022 ENSG00000131323 ENSG00000100219 ENSG00000171791 ENSG00000127191 ENSG00000135506 PMC9393521__F1 Current therapeutic strategies and perspectives in refractory ITP: What have we learned recently? ENSG00000186716 ENSG00000198793 ENSG00000010671 PMC2945029__F6 Pathways and networks related to chondrocyte proteins identified by proteomics as altered by GS and/or CS ENSG00000182718 PMC9699619__F2 Renin–Angiotensin-Aldosterone System, Nitric Oxide, and Hydrogen Sulfide at the Crossroads of Hypertension and COVID-19: Racial Disparities and Outcomes ENSG00000130234 PMC5877752__F1 Homocysteine (Hcy) metabolic pathway ENSG00000205221 PMC2730119__F3 Scheme showing the role of different signaling pathways in mediating the effect of high K intake on ROMK and BK channels in the CCD ENSG00000126562 ENSG00000060237 ENSG00000118515 PMC4167409__F1 Androgen biosynthesis in prostate cancer cells ENSG00000151632 ENSG00000203857 ENSG00000187134 PMC6298973__F8 Proposed TLR 2, 5, 8 signaling pathway ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC7064973__F2 Theorised DIS3L2 and let‐7 pathway mediating gastrointestinal nematode (GIN) resistance ENSG00000144535 ENSG00000131914 ENSG00000083223 ENSG00000134744 PMC2932783__F1 Targeting of signaling pathways by arsenic trioxide in chronic lymphocytic leukemia cells ENSG00000198793 PMC4028840__F1 PI3K/Akt/mTOR signaling pathway ] ENSG00000169047 PMC7203449__F4 Visualization of Gene Ontology (GO) enrichment profiles from DEGs using Cytoscape software based on network analysis of ClueGO/CluePedia inferred from MCODE cluster 1 (A) and cluster 2 (B) ENSG00000165891 ENSG00000134982 ENSG00000050748 ENSG00000010810 ENSG00000171848 ENSG00000197629 ENSG00000105810 ENSG00000112715 ENSG00000149554 ENSG00000100365 PMC5141617__F4 Conflict resolution in the genome: how transcription and replication make it work ENSG00000012048 ENSG00000175054 ENSG00000107290 ENSG00000260314 ENSG00000179632 ENSG00000128908 PMC4085491__F1 ELF4 in type I IFN signaling ENSG00000183735 ENSG00000088888 ENSG00000102034 ENSG00000276561 PMC10121353__F8 Main nodes of AGE-RAGE signaling pathway ENSG00000142192 ENSG00000173599 ENSG00000076706 PMC8198876__F1 Targeted Therapeutic Approach Based on Understanding of Aberrant Molecular Pathways Leading to Leukemic Proliferation in Patients with Acute Myeloid Leukemia ENSG00000198793 ENSG00000128602 PMC8758495__F3 Amyloidogenic vs non-amyloidogenic pathway ENSG00000142192 ENSG00000168615 PMC5727901__F1 Cyclin–CDK complexes and the cyclin D–CDK4/6–p16–Rb pathway in the cell cycleThe cell cycle is regulated by cyclins and checkpoints, with different cyclins (and cyclin–CDK combinations) and checkpoints acting at phase transition of the cell cycle ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 PMC7046305__F7 Anti‐tumour mechanism of Tan‐Ⅰ ENSG00000198793 PMC4898689__F8 Integrated Analysis of the Roles of Long Noncoding RNA and Coding RNA Expression in Sheep (Ovis aries) Skin during Initiation of Secondary Hair Follicle ENSG00000150991 PMC8284746__F2 Metabolic Control of Mouse and Human Astrocytes ENSG00000108691 ENSG00000088888 PMC4436984__F2 Key signaling regulation of autophagy in the heart ENSG00000177169 ENSG00000169047 PMC8814460__F2 Inflammation and Myeloid Cells in Cancer Progression and Metastasis ENSG00000189377 ENSG00000108691 ENSG00000107562 ENSG00000081041 ENSG00000163739 ENSG00000108688 ENSG00000108700 ENSG00000169429 ENSG00000118520 ENSG00000006606 ENSG00000168610 ENSG00000121966 PMC8814460__F1 Inflammation and Myeloid Cells in Cancer Progression and Metastasis ENSG00000177575 ENSG00000107562 ENSG00000081041 ENSG00000275385 ENSG00000158481 ENSG00000137033 ENSG00000163739 ENSG00000102970 ENSG00000106178 PMC8919643__F4 Untargeted metabolomics analysis of esophageal squamous cell cancer progression ENSG00000173599 ENSG00000153395 ENSG00000156471 PMC3321553__F2 Coregulation of gene transcription by p53 and Smad complexes PMC7290932__F5 Models for release of the Xenopus oocyte prophase block: probable cooperation between several receptors and downstream pathways ENSG00000172680 ENSG00000140443 PMC9661388__F6 Basal diet composition contributes to differential performance, intestinal health, and immunological responses to a microalgae-based feed ingredient in broiler chickens ENSG00000106617 ENSG00000069482 ENSG00000111837 ENSG00000197142 ENSG00000160216 ENSG00000102010 ENSG00000169299 ENSG00000101365 ENSG00000005469 PMC6664200__F3 Type I-IV mechanisms which aberrantly activate hedgehog pathway in cancer ENSG00000164690 ENSG00000128602 PMC6664200__F1 Diagrammatic representation of human hedgehog signaling pathway ENSG00000106571 ENSG00000166813 ENSG00000164690 ENSG00000128602 PMC7290932__F1 Diverse signalling pathways initiated by maturation initiation hormones (MIHs) lead to a universal biochemical core, activating maturation promoting factor (MPF) ENSG00000172680 ENSG00000128989 ENSG00000276876 PMC2175514__F5 Transcription regulatory network indicates utilization of various transcription factors following activation of TLR7 ENSG00000138378 ENSG00000187608 ENSG00000105397 ENSG00000056558 ENSG00000134070 ENSG00000026508 ENSG00000126353 ENSG00000276561 ENSG00000184216 PMC6008129__F1 Potential mitochondrial derangements that may be present in pulmonary hypertension are many and varied ENSG00000175567 ENSG00000138741 ENSG00000168610 PMC2175514__F9 Protein regulatory network indicates importance of ISGylation pathway in TLR7-mediated activation of pDC ENSG00000184979 ENSG00000181788 ENSG00000115415 ENSG00000131508 ENSG00000175104 ENSG00000077782 ENSG00000196628 PMC9705782__F1 Differentially expressed tRNA-derived fragments in bovine fetuses with assisted reproduction induced congenital overgrowth syndrome ENSG00000092847 ENSG00000134698 ENSG00000123908 PMC6233321__F1 Ceramide pools and their metabolic connection ENSG00000139624 ENSG00000100422 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000102172 ENSG00000143418 PMC3486512__F3 Network analysis of the host factors found to be associated with the extremities of the murine norovirus genome ENSG00000102753 ENSG00000090621 ENSG00000169710 ENSG00000108654 ENSG00000158517 ENSG00000197451 ENSG00000088247 ENSG00000169813 ENSG00000146731 ENSG00000171490 ENSG00000215301 ENSG00000009307 ENSG00000146676 ENSG00000165119 ENSG00000198242 ENSG00000167658 ENSG00000161970 ENSG00000115310 ENSG00000214753 ENSG00000170248 ENSG00000070756 ENSG00000122566 ENSG00000065978 ENSG00000011304 ENSG00000137076 ENSG00000163938 ENSG00000138668 PMC6658873__F1 Synergistic effect of three combined strategies by targeting complement/C3aR /C5aR1/IL-10 pathway and other treatment modalities ENSG00000089692 ENSG00000197405 PMC4164812__F1 BRAF inhibitors on melanoma and immune cells ENSG00000108691 ENSG00000157764 PMC9134690__F3 Effect of berberine on global modulation of lncRNAs and mRNAs expression profiles in patients with stable coronary heart disease ENSG00000144028 ENSG00000101115 ENSG00000108654 ENSG00000168002 ENSG00000101843 ENSG00000185615 ENSG00000155974 ENSG00000230034 ENSG00000181090 ENSG00000172216 ENSG00000182004 ENSG00000101654 ENSG00000166169 ENSG00000277707 ENSG00000101751 ENSG00000139343 ENSG00000285246 ENSG00000177733 ENSG00000274442 ENSG00000177189 ENSG00000147669 ENSG00000048052 ENSG00000074266 ENSG00000284944 ENSG00000256646 ENSG00000132341 ENSG00000111642 ENSG00000165494 PMC9091820__F2 Interaction Between Non-Coding RNAs and Interferons: With an Especial Focus on Type I Interferons ENSG00000213928 ENSG00000089127 ENSG00000140968 ENSG00000183486 ENSG00000157601 ENSG00000185885 ENSG00000171791 ENSG00000276561 ENSG00000142166 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000111331 ENSG00000184216 ENSG00000164342 PMC3951427__F12 New miRNA Profiles Accurately Distinguish Renal Cell Carcinomas and Upper Tract Urothelial Carcinomas from the Normal Kidney ENSG00000110514 ENSG00000136997 ENSG00000112378 ENSG00000074266 PMC12025219__F3 Changes in bone metabolism caused by cold environment ENSG00000105550 ENSG00000167941 PMC4567404__F1 A worm of one’s own: how helminths modulate host adipose tissue function and metabolism ENSG00000137033 PMC6862705__F5 SPRY-altered signaling network profiles in mammary stromal fibroblasts ENSG00000291971 ENSG00000154001 ENSG00000050748 ENSG00000177606 ENSG00000115020 ENSG00000040199 ENSG00000065559 ENSG00000143322 ENSG00000146648 ENSG00000187840 ENSG00000089159 PMC1756898__F1 Unraveling the Genetics of Human Obesity ENSG00000112964 ENSG00000115138 ENSG00000166603 PMC11814453__F4 The mechanism by which sodium channel inhibition exerts anti-tumor effects ENSG00000291971 ENSG00000198793 PMC11814453__F2 High salt or sodium ions on immune cells in the tumor microenvironment ENSG00000123685 ENSG00000162711 ENSG00000226275 ENSG00000198793 ENSG00000136869 ENSG00000091106 ENSG00000118520 ENSG00000168610 ENSG00000007171 PMC6770497__F8 Key metabolic pathway and regulatory network in mutant ptsd1 ENSG00000145020 ENSG00000084774 ENSG00000119125 PMC9141700__F3 Metabolite and Gene Expression Analysis Underlying Temporal and Spatial Accumulation of Pentacyclic Triterpenoids in Jujube ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC5885413__F3 LncRNAs regulate Rho/ROCK signaling in cancer metastasis ENSG00000087245 ENSG00000070831 ENSG00000156299 PMC5081730__F1 Epidermal growth factor receptor (EGFR)/extracellular signal-regulated kinases 1 and 2 (ERK1/2) signaling pathway ENSG00000164404 ENSG00000130385 ENSG00000109321 ENSG00000124882 ENSG00000146648 PMC3410320__F1 Survival and proliferative effects of Dilong extract on RSC96 Schwann cell ENSG00000138798 ENSG00000132646 ENSG00000122194 PMC10866157__F6 Schematic diagram depicting the mechanisms of 5-aza-dC treatment in inhibiting choroidal neovascularization in a laser-induced mouse model ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000185269 ENSG00000168646 PMC5864536__F1 Estradiol and the Control of Feeding Behavior ENSG00000115138 ENSG00000170893 PMC2650609__F6 Top network of upregulated genes in quadriceps muscles of COPD patients, compared with control subjects ENSG00000119138 ENSG00000150907 ENSG00000175567 ENSG00000131370 ENSG00000123689 ENSG00000141526 PMC4393798__F3 Overcoming T cell exhaustion in infection and cancer ENSG00000291603 ENSG00000134982 ENSG00000156127 PMC9369298__F3 diaPASEF Proteomics and Feature Selection for the Description of Sputum Proteome Profiles in a Cohort of Different Subtypes of Lung Cancer Patients and Controls ENSG00000110799 ENSG00000203710 ENSG00000088926 ENSG00000166278 ENSG00000122194 ENSG00000117322 ENSG00000185010 ENSG00000180210 ENSG00000126218 ENSG00000117525 ENSG00000057593 ENSG00000175899 ENSG00000080618 ENSG00000062485 PMC5457689__F6 Apoptosis pathway ENSG00000128272 ENSG00000084774 ENSG00000115317 PMC3928643__F4 IL-12 centred network analysis ENSG00000111537 ENSG00000105329 ENSG00000136869 ENSG00000113302 ENSG00000168811 PMC3928643__F3 IFNA/B and IL-4 centred pathway analysis ENSG00000159224 ENSG00000111537 ENSG00000147168 ENSG00000113520 PMC9704719__F6 Mono-(2-ethyl-5-hydroxyhexyl) phthalate promotes uterine leiomyoma cell survival through tryptophan-kynurenine-AHR pathway activation ENSG00000103257 ENSG00000106546 PMC7004522__F8 Working model shows that MET inhibitor inhibited the positive feedback loop between high STMN1 hepatocellular carcinoma (HCC) cells and hepatic stellate cells (HSC) ENSG00000019991 PMC11674327__F1 Extra-ribosomal functions of two RPs activating the NF-kB pathway during viral infection ENSG00000168028 ENSG00000153147 PMC5485730__F2 Interferon (IFN) type 1 signaling; regulation by methylation ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000070495 ENSG00000033800 ENSG00000126457 ENSG00000142166 PMC11933101__F1 Pyruvate synthesis pathway ENSG00000047597 ENSG00000158125 PMC6331187__F8 The mechanism of celastrol in TGFB/Smad signaling pathway PMC5347564__F1 Hippo signaling pathway is the only pathway enriched with up-regulated DEGs ENSG00000142192 ENSG00000122966 ENSG00000146648 PMC9119001__F3 Metabolic engineering of microorganisms for L-alanine production ENSG00000186063 PMC5407986__F2 Mitochondrial Control of Innate Immunity and Inflammation ENSG00000183735 ENSG00000106785 ENSG00000088888 ENSG00000102871 ENSG00000173599 ENSG00000160703 ENSG00000131323 ENSG00000162191 ENSG00000175104 ENSG00000127191 ENSG00000276561 PMC5407986__F1 Mitochondrial Control of Innate Immunity and Inflammation ENSG00000088888 ENSG00000115415 ENSG00000276561 ENSG00000142166 PMC3206369__F1 Primary phosphatases function as tumor suppressors and their signaling pathways ENSG00000124102 ENSG00000109452 ENSG00000198793 ENSG00000168036 PMC6321995__F2 Therapeutic strategy for downregulation of excess inflammatory mucus to normal physiological mucus levels, using a small-molecule kinase inhibitor of MAPK13 ENSG00000291363 ENSG00000016490 ENSG00000134982 PMC7646980__F10 Anti-inflammatory effects of BBR on LPS-induced inflammation via suppression of the TLR4/NFKB and MAPK/AP-1 pathways ENSG00000170458 ENSG00000125538 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000185187 ENSG00000130159 ENSG00000175104 ENSG00000184216 PMC8739177__F1 Exploration of the Danggui Buxue Decoction Mechanism Regulating the Balance of ESR and AR in the TP53-AKT Signaling Pathway in the Prevention and Treatment of POF ENSG00000095794 ENSG00000127948 PMC8739177__F3 Exploration of the Danggui Buxue Decoction Mechanism Regulating the Balance of ESR and AR in the TP53-AKT Signaling Pathway in the Prevention and Treatment of POF ENSG00000087245 ENSG00000157404 ENSG00000086696 ENSG00000165841 ENSG00000129214 ENSG00000140505 ENSG00000128052 ENSG00000103222 ENSG00000100985 ENSG00000106546 PMC5996447__F8 Hei-Gu-Teng Zhuifenghuoluo granule and the IL-12 signaling pathway ENSG00000096996 ENSG00000138378 ENSG00000125538 PMC9219782__F1 Cell Death-Related Ubiquitin Modifications in Inflammatory Syndromes: From Mice to Men ENSG00000278718 ENSG00000183735 ENSG00000137275 ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000154124 ENSG00000127191 ENSG00000164305 ENSG00000285379 PMC4470863__F2 Commitment and maintenance of gonadal cell fate ENSG00000162552 ENSG00000169218 ENSG00000186766 ENSG00000125398 ENSG00000102678 PMC8739177__F4 Exploration of the Danggui Buxue Decoction Mechanism Regulating the Balance of ESR and AR in the TP53-AKT Signaling Pathway in the Prevention and Treatment of POF ENSG00000087245 ENSG00000129214 ENSG00000128052 ENSG00000100985 ENSG00000140465 ENSG00000106546 PMC4112160__F2 Surviving Change: The Metabolic Journey of Hematopoietic Stem Cells ENSG00000198793 PMC5412370__F1 Specific elements of the canonical pathway for modulation of gene expression that are activated after 15 min of exposure of U118MG cells to 25 µM of PK 11195, as uncovered by “Regulator Effects” analytic (IPA®) ENSG00000002330 ENSG00000291971 ENSG00000138798 ENSG00000060237 ENSG00000136997 ENSG00000128342 ENSG00000146648 PMC3247990__F8 Post-induction repression of IFNB expression by YY1 in TLR3 signaling pathway ENSG00000100811 ENSG00000104856 ENSG00000183735 ENSG00000276561 ENSG00000164342 PMC6325472__F1 PI3K pathway activation and cell-cycle in tumor cells ENSG00000124102 ENSG00000135446 ENSG00000166278 ENSG00000105810 PMC2835907__F3 Synopsis of FGFR2b-mediated dermal-epithelial signaling in keratinocytes and sebocytes of sebaceous glands ENSG00000070193 ENSG00000138798 ENSG00000140285 ENSG00000164690 ENSG00000146648 ENSG00000140443 PMC2735462__F3 Ubiquitin in NFKB Signaling ENSG00000088888 ENSG00000102871 ENSG00000083799 PMC3148288__F1 ERM proteins are scaffolds for cAMP signaling pathways ENSG00000165527 PMC9092946__F1 Endoplasmic Reticulum Stress and Its Role in Homeostasis and Immunity of Central and Peripheral Neurons ENSG00000278718 ENSG00000162711 ENSG00000128272 ENSG00000144895 ENSG00000125538 ENSG00000136997 PMC3109512__F3 Proposed role of CnPlc1 in pathogenicity-related signaling in C ENSG00000177464 ENSG00000062485 PMC7319438__F1 SPEED2 application We manually selected pathway-specific perturbation experiments and estimated their pathway-relevance ENSG00000160888 ENSG00000113070 ENSG00000274538 PMC3922094__F2 Pancreatic cancer pathway diagram ENSG00000163235 ENSG00000138798 PMC9682072__F3 Viral tropism for the testis and sexual transmission ENSG00000169245 ENSG00000164430 ENSG00000187608 ENSG00000187554 ENSG00000157601 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC8558658__F7 Hey1 promotes migration and invasion of melanoma cells via GRB2/PI3K/AKT signaling cascade PMC6983753__F5 Likely pathogenic mutations restricted in the metastases affect DNA methylation and transcriptional repression signaling pathway ENSG00000057935 ENSG00000071655 ENSG00000088305 ENSG00000162521 ENSG00000150459 ENSG00000134046 ENSG00000169375 ENSG00000149480 ENSG00000111642 ENSG00000164105 PMC6803376__F5 In the presence of the Ter mutation in Dnd1, members of mTOR, Hippo and Bmp/Nodal pathways have altered expression, with some transcripts indicated as direct targets of DND1 ENSG00000170365 ENSG00000126016 ENSG00000117020 ENSG00000170027 ENSG00000241186 ENSG00000198793 ENSG00000156574 ENSG00000118515 ENSG00000164327 ENSG00000141564 PMC1557712__F2 Molecular control of alveolar morphogenesis ENSG00000162552 ENSG00000120833 ENSG00000082175 ENSG00000105329 ENSG00000184524 ENSG00000168036 ENSG00000100664 ENSG00000178568 PMC2346559__F1 An Allosteric Mechanism for Switching between Parallel Tracks in Mammalian Sulfur Metabolism ENSG00000174197 PMC9630750__F2 Drosophila melanogaster as a model to study innate immune memory ENSG00000172936 ENSG00000162924 ENSG00000168040 PMC2716801__F1 Schematic illustration of the Warburg effect in tumor cells and in early asymptomatic endothelial cell dysfunction ENSG00000078237 ENSG00000127884 PMC6034857__F5 Transcriptome study on Macrobrachium nipponense hepatopancreas experimentally challenged with white spot syndrome virus (WSSV) ENSG00000003056 ENSG00000135218 ENSG00000170458 ENSG00000168818 ENSG00000248109 ENSG00000079950 ENSG00000136869 ENSG00000005381 ENSG00000274145 PMC8705789__F3 The Inflammatory Response in Mediating Functional Recovery Following Composite Tissue Injuries ENSG00000163599 ENSG00000198793 PMC10308199__F3 Cysteine dioxygenase type 1 (CDO1): Its functional role in physiological and pathophysiological processes ENSG00000129596 ENSG00000139531 PMC4163898__F1 Stress-induced premature senescence (SIPS) signaling pathway ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000105810 PMC10380929__F3 PINNet: a deep neural network with pathway prior knowledge for Alzheimer's disease ENSG00000157404 ENSG00000167207 ENSG00000120885 ENSG00000100485 ENSG00000072210 ENSG00000247626 ENSG00000136997 ENSG00000277263 ENSG00000179348 ENSG00000146701 ENSG00000142192 ENSG00000292149 ENSG00000132356 ENSG00000104888 ENSG00000224320 ENSG00000131480 ENSG00000154188 ENSG00000127948 ENSG00000152556 ENSG00000019991 ENSG00000070831 ENSG00000119508 ENSG00000291971 ENSG00000196591 ENSG00000149782 ENSG00000123104 ENSG00000169032 ENSG00000121879 ENSG00000137801 ENSG00000179295 ENSG00000150782 ENSG00000166501 ENSG00000123374 ENSG00000121853 ENSG00000125166 ENSG00000163399 ENSG00000104365 ENSG00000160883 ENSG00000116044 ENSG00000109320 ENSG00000196839 ENSG00000173039 ENSG00000089041 ENSG00000182621 ENSG00000087460 ENSG00000149311 ENSG00000066468 ENSG00000007168 ENSG00000115956 ENSG00000116106 ENSG00000152904 ENSG00000167535 ENSG00000100985 ENSG00000128602 ENSG00000116761 ENSG00000159399 ENSG00000204217 PMC8261290__F3 Intracellular Interactions Between Arboviruses and Wolbachia in Aedes aegypti ENSG00000119655 ENSG00000172936 PMC10992626__F2 Simplified illustration showing key pathways involved in disc degeneration ENSG00000154736 ENSG00000157766 ENSG00000168610 ENSG00000158859 PMC9221885__F1 New Insights into Neuroinflammation Involved in Pathogenic Mechanism of Alzheimer’s Disease and Its Potential for Therapeutic Intervention ENSG00000162711 ENSG00000164430 ENSG00000198793 PMC8970588__F8 Simplified model showing how availability of the dedicated chaperone Rrb1 or Acl4 and the here uncovered regulatory network cooperate to balance Rpl3 and Rpl4 expression by co-translationally regulating RPL3 and RPL4 mRNA levels ENSG00000174444 PMC3103989__F1 Endocrine, paracrine and autocrine regulation of the IGF-1R pathway and therapeutic strategies for its disruption ENSG00000169291 ENSG00000197081 ENSG00000291972 ENSG00000198793 ENSG00000140443 PMC8656811__F3 Genome Instability in Multiple Myeloma: Facts and Factors ENSG00000166349 ENSG00000150907 ENSG00000186716 ENSG00000137265 ENSG00000189403 ENSG00000196092 ENSG00000112182 ENSG00000100219 ENSG00000175097 PMC10037588__F6 Reassessing the Abundance of miRNAs in the Human Pancreas and Rodent Cell Lines and Its Implication ENSG00000171105 ENSG00000002330 ENSG00000110395 ENSG00000150907 ENSG00000164087 ENSG00000026103 PMC6071487__F2 Interleukin 6 (IL-6) receptor-mediated signaling pathway and an IL-6 inhibitor, the humanized anti-IL-6 receptor antibody tocilizumab ENSG00000110448 ENSG00000168610 PMC6071487__F3 Arid5a stabilizes interleukin 6 (IL-6) and Stat3 messenger RNAs (mRNAs) ENSG00000196843 ENSG00000172936 ENSG00000136869 ENSG00000131096 ENSG00000168610 PMC9623116__F4 Deregulated calcium signaling in blood cancer: Underlying mechanisms and therapeutic potential ENSG00000095585 ENSG00000167323 ENSG00000293604 ENSG00000156026 ENSG00000186716 ENSG00000010671 PMC4484611__F6 Cell adhesion molecules (CAMs) pathway ENSG00000149564 ENSG00000135218 ENSG00000169896 ENSG00000081237 ENSG00000134982 ENSG00000179242 ENSG00000163599 ENSG00000170558 ENSG00000173482 ENSG00000105656 ENSG00000007908 ENSG00000010278 ENSG00000150637 ENSG00000292348 ENSG00000116815 ENSG00000188404 ENSG00000158887 ENSG00000154721 PMC11694080__F7 Fluxes of glycolysis, pentose phosphate, and TCA cycle pathways in hMφ treated with DETA‐NO and CK ENSG00000197713 ENSG00000104237 ENSG00000148926 ENSG00000173599 ENSG00000178445 PMC4872639__F8 Gq-dependent signalling by the lysophosphatidic acid receptor LPA3 in gastric smooth muscle: reciprocal regulation of MYPT1 phosphorylation by Rho kinase and cAMP-independent PKA ENSG00000163914 ENSG00000198670 PMC3954954__F6 Tissue Factor Inflammatory Response Regulated by Promoter Genotype and p38 MAPK in Neonatal vs. Adult Microvascular Endothelial Cells ENSG00000102871 ENSG00000185591 ENSG00000168610 PMC8465200__F1 Association between Polymorphisms in Vitamin D Pathway-Related Genes, Vitamin D Status, Muscle Mass and Function: A Systematic Review ENSG00000111012 ENSG00000152266 ENSG00000172893 ENSG00000105516 ENSG00000019186 ENSG00000107611 ENSG00000036828 ENSG00000186104 ENSG00000135929 PMC7216841__F1 Latency reversing agents induce HIV‐1 provirus replication by diverse mechanisms ENSG00000136807 ENSG00000174720 ENSG00000141867 ENSG00000146834 ENSG00000062485 PMC3406727__F1 Simplified schematic drawing of metabolic pathways in Chlamydomonas reinhardtii (adapted from Ref ENSG00000039537 ENSG00000166278 PMC5927619__F2 Pathway diagram for IL-2 family signaling showing the increase in detail level as zoom level increases ENSG00000291971 ENSG00000284984 PMC5927619__F1 Enhanced high-level diagram (EHLD) for signaling by interleukins ENSG00000150782 ENSG00000105397 ENSG00000115415 ENSG00000115904 ENSG00000105639 ENSG00000175104 ENSG00000168610 ENSG00000160691 ENSG00000179295 PMC5758399__F2 Top section: Mechanisms responsible for the cytoprotective and anti‐inflammatory effects of PARP inhibitors on non‐oncological diseases ENSG00000169621 ENSG00000118518 ENSG00000108691 ENSG00000134574 ENSG00000039650 ENSG00000177606 ENSG00000168036 ENSG00000227345 ENSG00000138385 PMC5453942__F3 Map of DEGs in Oncopig leiomyosarcomas and their functions within the TP53 signaling pathway ENSG00000132906 ENSG00000149212 ENSG00000085117 ENSG00000175793 ENSG00000099860 ENSG00000118971 ENSG00000164305 ENSG00000124762 ENSG00000080546 ENSG00000137801 ENSG00000175054 ENSG00000048392 ENSG00000134057 ENSG00000130222 ENSG00000112378 ENSG00000075218 ENSG00000120868 ENSG00000147082 ENSG00000026103 PMC2410298__F1 TOLL-LIKE RECEPTORS REGULATION OF VIRAL INFECTION AND DISEASE ENSG00000174125 ENSG00000239732 ENSG00000088888 ENSG00000136869 ENSG00000164342 PMC5453942__F4 Map of DEGs in Oncopig STS cell lines and their functions within the TP53 signaling pathway ENSG00000175793 ENSG00000134057 ENSG00000198793 ENSG00000130222 ENSG00000112378 ENSG00000075218 ENSG00000105810 ENSG00000147082 ENSG00000164305 ENSG00000115107 ENSG00000124762 ENSG00000080546 PMC9623116__F1 Deregulated calcium signaling in blood cancer: Underlying mechanisms and therapeutic potential ENSG00000167323 ENSG00000156026 ENSG00000109689 PMC4236713__F8 TBB through the non-mevalonate pathway and gene annotation in T ENSG00000122966 ENSG00000172005 ENSG00000197429 PMC11354688__F5 Process of human steroidogenesis ENSG00000086696 ENSG00000108786 ENSG00000203859 ENSG00000176387 PMC5352388__F7 N-cadherin promotes thyroid tumorigenesis through modulating major signaling pathways ENSG00000087245 ENSG00000137673 ENSG00000157227 ENSG00000170558 ENSG00000100985 PMC7611845__F1 Driver pathways in the pathogenesis of marginal zone lymphoma ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000198793 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000010671 ENSG00000198286 PMC2944186__F1 Convergence between Wnt and EGFR pathways ENSG00000281324 ENSG00000162337 ENSG00000163235 ENSG00000168036 ENSG00000276920 ENSG00000146648 PMC8074257__F4 Revisiting the Impact of Local Leptin Signaling in Folliculogenesis and Oocyte Maturation in Obese Mothers ENSG00000145321 PMC4918710__F1 Alternate complement pathway ENSG00000274619 ENSG00000039537 ENSG00000113600 ENSG00000000971 ENSG00000178726 PMC4760064__F3 Gene regulation by peroxisome proliferators (PPARs): the most significant pathway from Crohn’s disease (CD) ENSG00000130164 ENSG00000177606 ENSG00000185591 PMC8074257__F1 Revisiting the Impact of Local Leptin Signaling in Folliculogenesis and Oocyte Maturation in Obese Mothers ENSG00000178188 ENSG00000150907 ENSG00000198793 ENSG00000168610 PMC2891948__F2 Addicted Synapse: Mechanisms of Synaptic and Structural Plasticity in Nucleus Accumbens ENSG00000184845 ENSG00000149295 PMC7395869__F1 Means to inhibit canonical HH, WNT and NOTCH pathways ENSG00000102312 ENSG00000168036 ENSG00000128602 PMC7905009__F3 Scheme representing the different regenerative processes promoted by TGFB/activin signaling ENSG00000262406 ENSG00000177426 ENSG00000136535 ENSG00000105329 PMC6605064__F1 Schematic diagram illustrating the UPR signal transduction pathway ENSG00000139437 ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000171791 PMC6391951__F11 Illustration of most of the proposed modes of action of antitumoral POMs ENSG00000124479 ENSG00000112715 PMC7810549__F9 Xiaoyaosan exerts its antidepressive effects in rats with chronic restraint-induced stress via regulating the activation of the immunoinflammatory response induced by the TLR4/NLRP3 inflammasome signaling pathway in the colon ENSG00000162711 ENSG00000136869 ENSG00000175104 PMC8546956__F7 Comparative phenotypic and transcriptomic analyses unravel conserved and distinct mechanisms underlying shade avoidance syndrome in Brassicaceae vegetables ENSG00000133116 ENSG00000128052 ENSG00000173599 ENSG00000062485 PMC8128982__F4 Depicting the proposed pathogenesis of MIS-C with COVID-19 (the proposed pathogenesis is a constellation of various hypotheses referred accordingly) ENSG00000151882 ENSG00000159128 ENSG00000169550 ENSG00000122223 ENSG00000145194 ENSG00000176435 ENSG00000112715 ENSG00000135124 ENSG00000145113 ENSG00000115009 PMC3997957__F1 Cell cycle arrest by CDKN2A ENSG00000135446 PMC6445394__F1 RIG-I, MDA5, LGP2, PKR, and TLRs3/7/8 are activated during viral infection in the presence of non-self dsRNA ENSG00000184979 ENSG00000183735 ENSG00000088888 ENSG00000115415 ENSG00000160710 ENSG00000172936 ENSG00000168040 ENSG00000164342 PMC6651977__F1 The ER stress pathway ENSG00000128272 ENSG00000144895 ENSG00000198626 ENSG00000100219 PMC9251145__F9 Salvianolic Acid B Attenuates Iopromide-Induced Renal Tubular Epithelial Cell Injury by Inhibiting the TLR4/NFKB/NLRP3 Signaling Pathway ENSG00000162711 ENSG00000173039 ENSG00000172936 ENSG00000136869 ENSG00000162924 PMC8466696__F3 Comparison of the transcriptome in circulating leukocytes in early lactation between primiparous and multiparous cows provides evidence for age-related changes ENSG00000141349 ENSG00000159322 ENSG00000124253 ENSG00000169299 ENSG00000152556 PMC9462548__F1 The JNK Pathway in Bladder Cancer ENSG00000002330 ENSG00000291971 ENSG00000198793 ENSG00000057663 PMC5572386__F2 Apoptotic and necroptotic mechanisms ENSG00000102871 ENSG00000083799 ENSG00000171791 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000084774 PMC3098789__F6 Portion of the 'Toll-like Receptor Signaling' pathway for two representative cell lines ENSG00000239732 ENSG00000168040 ENSG00000064012 PMC2593566__F3 JAK/STAT signaling pathway and SARS-CoV ENSG00000213928 ENSG00000115415 PMC10452461__F2 Fusobacterium affects chemotherapy drugs ENSG00000172936 ENSG00000136869 PMC4986142__F1 Resistance to RAF inhibitors ENSG00000157764 ENSG00000196712 PMC5959917__F6 Schematic diagram explaining the mechanism of CSC maintenance in cervical cancer via let-7i-5p, miR-181a-2-3p and EGF/PI3K/SOX2 axis ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC7424006__F10 TLR4 had an important proatherogenic role in monocytes/macrophages ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000162692 ENSG00000175104 PMC4997609__F6 Wedelolactone enhances osteoblastogenesis by regulating Wnt/Beta-catenin signaling pathway but suppresses osteoclastogenesis by NFKB/c-fos/NFATc1 pathway ENSG00000168036 ENSG00000131196 PMC4724343__F3 Because KAT2B is a novel genetic susceptibility factor for drug abuse, we built a GeneMANIA () network centered around KAT2B to find related genes that may have functional links to drug abuse ENSG00000071564 ENSG00000170365 ENSG00000115750 ENSG00000165733 ENSG00000005339 ENSG00000283780 ENSG00000184384 ENSG00000074181 ENSG00000114166 ENSG00000100603 PMC8112447__F4 Zebrafish Cancer Predisposition Models ENSG00000110395 ENSG00000198793 ENSG00000115904 ENSG00000196712 PMC8112447__F3 Zebrafish Cancer Predisposition Models ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC7697917__F11 Enrichment of the neuroinflammatory pathway in microglia in cluster 1, based on the DEGs between cluster 1 and clusters 2–5 ENSG00000157368 ENSG00000184995 ENSG00000113520 ENSG00000132693 ENSG00000276561 ENSG00000062485 PMC8226020__F5 Calcium Binding Protein S100A11 and Its Roles in Diseases ENSG00000168036 PMC9149100__F7 Figure 3.Effect of CDK4 and CDK6 inhibition upon tumour cell-intrinsic and -extrinsic signalling pathways ENSG00000135446 ENSG00000198793 ENSG00000164327 ENSG00000123374 ENSG00000105810 PMC8112447__F7 Zebrafish Cancer Predisposition Models ENSG00000012061 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000183763 ENSG00000144554 ENSG00000188827 ENSG00000187790 ENSG00000108384 ENSG00000051180 ENSG00000276787 ENSG00000139618 PMC7071697__F3 Complex mechanisms and signaling pathways underlying VM formation ENSG00000169554 PMC9149100__F1 CDK4 and CDK6 pathway in cancer ENSG00000135446 ENSG00000131747 ENSG00000168036 ENSG00000123374 ENSG00000105810 PMC3108692__F1 Mammalian target of rapamycin (mTOR) network ENSG00000198793 ENSG00000167965 PMC9420941__F4 Novel perspectives on the therapeutic role of cryptotanshinone in the management of stem cell behaviors for high-incidence diseases ENSG00000181019 ENSG00000079999 PMC9420941__F5 Novel perspectives on the therapeutic role of cryptotanshinone in the management of stem cell behaviors for high-incidence diseases ENSG00000129474 ENSG00000126016 ENSG00000149930 ENSG00000203485 ENSG00000160551 ENSG00000160867 ENSG00000135090 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC5391240__F5 MiR-34a-3p alters proliferation and apoptosis of meningioma cells in vitro and is directly targeting SMAD4, FRAT1 and BCL2 ENSG00000134982 ENSG00000165879 ENSG00000168036 ENSG00000171791 PMC4662480__F6 Integrated analysis of microRNAs, transcription factors and target genes expression discloses a specific molecular architecture of hyperdiploid multiple myeloma ENSG00000105397 ENSG00000291971 ENSG00000168610 PMC11743736__F1 Lipid metabolism pathways and promising targets for breast cancer treatment ENSG00000157184 ENSG00000131473 ENSG00000130164 ENSG00000173599 ENSG00000113161 ENSG00000104549 ENSG00000026103 PMC4055918__F1 Erythroid DAMPs drive inflammation in SCD ENSG00000177575 ENSG00000213918 ENSG00000136869 PMC5620554__F2 TRIMs in cytokine signaling ENSG00000112343 ENSG00000102871 ENSG00000171206 ENSG00000121236 ENSG00000127191 ENSG00000168610 ENSG00000105397 ENSG00000115415 ENSG00000157625 ENSG00000172936 ENSG00000122779 ENSG00000184216 ENSG00000130726 PMC6175656__F3 TRPCing around the Hypothalamus ENSG00000115138 PMC5000685__F2 Diagram of LPS-induced TLR4 signaling ENSG00000170458 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000130159 ENSG00000175104 PMC3691765__F1 Apoptotic signaling pathways ENSG00000168040 ENSG00000084774 ENSG00000026103 PMC3691765__F4 HTLV-1 and apoptotic signaling pathways ENSG00000002330 PMC8351892__F1 Tracing the roots of CLPD-NK by TET2 and STAT3 ENSG00000168610 PMC3983582__F2 Nucleotide excision repair (NER): the proteins associated with human diseases are highlighted ENSG00000012061 ENSG00000132646 PMC2645908__F5 Model showing RBR3 role in the RBR/E2F pathway controlling the expression of MCM2–7 genes, DNA replication, and cell transformation ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000166508 PMC12110399__F3 LGR5 potentiates the WNT–Beta-catenin signaling pathway that maintains the stem-cell-like phenotype, impeding cellular differentiation ENSG00000281324 ENSG00000162337 ENSG00000183579 ENSG00000108375 PMC9579211__F3 Ethnomedicinal uses of Indian spices used for cancer treatment: A treatise on structure-activity relationship and signaling pathways ENSG00000198793 PMC5753667__F2 The mammalian polyamine pathway ENSG00000088826 ENSG00000148832 ENSG00000116649 ENSG00000102172 PMC10521506__F10 Milk thistle nano-micelle formulation promotes cell cycle arrest and apoptosis in hepatocellular carcinoma cells through modulating miR-155-3p /SOCS2 /PHLDA1 signaling axis ENSG00000120833 ENSG00000139289 PMC9579211__F4 Ethnomedicinal uses of Indian spices used for cancer treatment: A treatise on structure-activity relationship and signaling pathways PMC9579211__F6 Ethnomedicinal uses of Indian spices used for cancer treatment: A treatise on structure-activity relationship and signaling pathways ENSG00000137845 ENSG00000182667 PMC5150411__F1 Metabolic pathways expressed in the deep subsurface ENSG00000261701 ENSG00000197713 ENSG00000084774 ENSG00000116984 PMC9389535__F2 Therapeutic approaches to colorectal cancer via strategies based on modulation of gut microbiota ENSG00000150782 ENSG00000111537 ENSG00000145777 PMC9175089__F6 Polyisoprenylated Cysteinyl Amide Inhibitors: A Novel Approach to Controlling Cancers with Hyperactive Growth Signaling ENSG00000070831 ENSG00000138798 PMC4304082__F2 Piece #2: The BCL-2 family controls BAK/BAX activation and MOMP ENSG00000002330 PMC4304082__F1 Piece #1: Tumor suppressor and oncogenic pathways converge on the mitochondrial pathway of apoptosis ENSG00000132906 ENSG00000136997 PMC6407368__F2 Ca2+signaling pathways in Beta-cells ENSG00000157540 ENSG00000170145 ENSG00000160741 PMC6398521__F4 Effect of 1,25(OH)2D3 and AB on the key reactions involved in the sphingolipid metabolic pathway ENSG00000139624 ENSG00000100422 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000145321 ENSG00000143418 PMC6662982__F8 In metabolic syndrome, hyperglycemia, and hyperlipidemia cause nutrient overinflux to kidney cells leading to increased celllular metabolism, which elevates intracelluar levels of citrate and ATP ENSG00000135218 ENSG00000113161 ENSG00000026103 PMC10478980__F4 Process of apoptosis ENSG00000102871 ENSG00000120868 ENSG00000171791 ENSG00000168040 ENSG00000026103 PMC3444148__F1 Nodal signaling pathway in melanoma ENSG00000133937 ENSG00000156574 PMC3304012__F3 Landscape of EGFR Signaling Network in Human Cancers: Biology and Therapeutic Response in Relation to Receptor Subcellular Locations ENSG00000138798 ENSG00000166260 ENSG00000146648 PMC10478980__F1 Process of necroptosis ENSG00000162711 ENSG00000137275 ENSG00000102871 ENSG00000136869 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC8945338__F3 Some Insights into the Regulation of Cardiac Physiology and Pathology by the Hippo Pathway ENSG00000186575 ENSG00000099985 ENSG00000157601 ENSG00000168036 ENSG00000114978 PMC7655915__F7 Proposed model of the stimulatory effect of growth differentiation factor 8 (GDF8) on relative transwell cells in human trophoblast cells ENSG00000070404 PMC5485291__F2 MTOR signaling pathway and the possibility of curcumin's pharmacological action on the pathway in the treatment of SCI ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC8945338__F2 Some Insights into the Regulation of Cardiac Physiology and Pathology by the Hippo Pathway ENSG00000142192 ENSG00000168036 ENSG00000164093 ENSG00000150457 ENSG00000131023 PMC5888808__F1 Programmed death-ligand 1 (PD-L1) is the ligand of programmed death 1 (PD-1) receptor ENSG00000111537 ENSG00000115415 ENSG00000291971 ENSG00000198793 ENSG00000168264 ENSG00000168310 ENSG00000168610 ENSG00000146648 ENSG00000230034 PMC4809260__F2 Oxidative stress under ambient and physiological oxygen tension in tissue culture ENSG00000173039 ENSG00000136869 ENSG00000079999 PMC4188627__F3 Methamphetamine Alters the Normal Progression by Inducing Cell Cycle Arrest in Astrocytes ENSG00000144063 ENSG00000105664 ENSG00000065833 ENSG00000138346 ENSG00000132646 ENSG00000123374 ENSG00000164754 PMC3565254__F2 Pathways involved in endocrine resistance ENSG00000291971 ENSG00000113070 ENSG00000185591 ENSG00000146648 PMC11172744__F7 After TCR stimulation, two signaling pathways are induced via 3,4,5-triphosphate (IP3) and diacylglycerol (DAG) ENSG00000291603 ENSG00000213658 ENSG00000159322 ENSG00000124181 PMC3335396__F1 Ligand-dependent activation of the Hh pathway ENSG00000164690 ENSG00000128602 PMC9350412__F7 SARS‐CoV‐2 ORF10 antagonizes STING‐dependent interferon activation and autophagy ENSG00000183735 ENSG00000164430 ENSG00000130234 PMC3385714__F3 Paralvinella conceptual glutathione pathway and responses to thermal exposure ENSG00000099864 PMC2180215__F1 Comparison of the protein kinase/phosphatase signaling pathways in flies, worms, and humans (see text for description) ENSG00000291603 ENSG00000070831 ENSG00000291971 ENSG00000172936 PMC8316205__F5 Estrogen- and Progesterone (P4)-Mediated Epigenetic Modifications of Endometrial Stromal Cells (EnSCs) and/or Mesenchymal Stem/Stromal Cells (MSCs) in the Etiopathogenesis of Endometriosis ENSG00000141232 ENSG00000253293 ENSG00000004478 ENSG00000005073 ENSG00000164040 ENSG00000138798 PMC8960399__F2 Proposed signaling pathways underlying the antidepressant-like actions of arketamine and TGFB1 PMC7758413__F5 Gene function network revealed a core role of the AP-1 linked signaling pathways during the recovery of COVID-19 ENSG00000163464 ENSG00000081041 ENSG00000111537 ENSG00000177606 ENSG00000169429 ENSG00000121966 ENSG00000069667 PMC8105091__F9 Mogroside V Alleviates Lipopolysaccharide-Induced Neuroinflammation via Inhibition of TLR4-MyD88 and Activation of AKT/AMPK-Nrf2 Signaling Pathway ENSG00000172936 ENSG00000136869 ENSG00000023909 PMC8026647__F4 Reconstructing directed transcriptional networks and master regulators in ccRCC ENSG00000167601 ENSG00000138639 ENSG00000170558 ENSG00000159461 ENSG00000095015 ENSG00000166508 ENSG00000182749 ENSG00000129219 ENSG00000136986 ENSG00000127663 ENSG00000073060 ENSG00000111875 ENSG00000157227 ENSG00000165023 ENSG00000167840 ENSG00000143622 ENSG00000160179 ENSG00000043039 ENSG00000071539 ENSG00000128918 ENSG00000000003 ENSG00000186867 ENSG00000173210 ENSG00000134504 ENSG00000276043 ENSG00000288210 ENSG00000102878 ENSG00000291754 ENSG00000164050 ENSG00000135638 ENSG00000146592 ENSG00000197857 ENSG00000221994 ENSG00000168916 ENSG00000182986 ENSG00000105643 PMC5366136__F5 Relationship between the nine DEGs in network 1 in the Jerseys ENSG00000182400 ENSG00000167632 ENSG00000133574 ENSG00000011376 ENSG00000242616 ENSG00000171115 ENSG00000105379 ENSG00000284228 PMC5366136__F4 Relationship between 18 DEGs in network 1 in the Holsteins ENSG00000066468 ENSG00000170522 ENSG00000204634 ENSG00000062282 PMC5543131__F5 Differentially active pathways across pan-urologic genomic subtypes ENSG00000067992 ENSG00000117118 ENSG00000169710 ENSG00000135069 ENSG00000146733 ENSG00000065833 ENSG00000186575 ENSG00000074800 ENSG00000100412 ENSG00000146701 ENSG00000091140 ENSG00000169299 ENSG00000113645 ENSG00000039537 ENSG00000197713 ENSG00000113600 ENSG00000160883 ENSG00000067057 ENSG00000108515 ENSG00000005882 ENSG00000153574 ENSG00000105953 ENSG00000166278 ENSG00000166816 ENSG00000150457 ENSG00000131023 ENSG00000131828 ENSG00000079999 ENSG00000284320 ENSG00000143252 ENSG00000172840 ENSG00000159399 ENSG00000152556 ENSG00000139410 PMC4894314__F1 Effect of HDACI on cell survival signaling pathway in hemorrhagic shock ENSG00000168036 PMC6211728__F7 Phenethyl isothiocyanate activates leptin signaling and decreases food intake ENSG00000115138 PMC4894314__F4 TLR4 signaling – a converged immune response pathway for hemorrhagic shock and septic shock ENSG00000172936 ENSG00000136869 PMC5597045__F2 RNAi-based biosynthetic pathway screens to identify in vivo functions of non-nucleic-acid-based metabolites such as lipids ENSG00000066336 PMC5597045__F1 RNAi-based biosynthetic pathway screens to identify in vivo functions of non-nucleic-acid-based metabolites such as lipids ENSG00000083857 ENSG00000165323 PMC6283154__F6 Summarization of DDT pathway selection in spn1 strains ENSG00000178966 PMC4923130__F1 Glucocorticoid-mediated modulation of pro-inflammatory pathways ENSG00000145321 ENSG00000172936 ENSG00000136869 PMC3587991__F1 P53 signaling pathway interacts with chromatin-remodeling factors in response to DNA damage ENSG00000012048 ENSG00000096717 ENSG00000183495 PMC5564318__F3 Up and down-regulated metabolic proteins in PANC-1 cells ENSG00000062485 PMC3587991__F2 Chromatin-remodeling factors affect the cell cycle ENSG00000149311 ENSG00000066923 ENSG00000108055 ENSG00000159399 ENSG00000111642 PMC8286839__F7 Feedback inhibition arising from NFKB activation operates at all levels in the pathway ENSG00000185187 PMC8286839__F6 Canonical and non-canonical NFKB signalling pathways ENSG00000104856 ENSG00000102871 ENSG00000136869 ENSG00000112186 ENSG00000127191 PMC8279535__F3 Premature Senescence of T-cells Favors Bone Loss During Osteolytic Diseases. A New Concern in the Osteoimmunology Arena ENSG00000169884 ENSG00000049768 PMC10376369__F7 Alzheimer’s Disease and Green Tea: Epigallocatechin-3-Gallate as a Modulator of Inflammation and Oxidative Stress PMC3188682__F3 TGFB1/SMAD3 signaling as an integrator of fibrotic mechanisms in the kidney ENSG00000019991 ENSG00000157933 ENSG00000291971 ENSG00000135253 ENSG00000105698 ENSG00000146648 PMC10376369__F5 Alzheimer’s Disease and Green Tea: Epigallocatechin-3-Gallate as a Modulator of Inflammation and Oxidative Stress ENSG00000002330 ENSG00000117298 PMC3727840__F2 TGFB in bone metastasis: novel therapeutic perspectives ENSG00000070831 PMC4922502__F2 Actionable drugs in proliferation pathway that have been evaluated in BRAFmut CRC ENSG00000157764 ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC8906035__F1 Kynurenine pathway in Coronavirus disease (COVID‐19): Potential role in prognosis ENSG00000111537 ENSG00000188676 PMC6530343__F2 Target sites of therapeutics along the pathogenetic pathway of celiac disease ENSG00000183625 ENSG00000231179 ENSG00000204520 ENSG00000164949 PMC6509151__F4 The role of FcμR in central deletion and B cell repertoire selection ENSG00000166349 ENSG00000162894 ENSG00000132465 ENSG00000150907 PMC5718814__F2 Molecular mechanisms of DNA vaccines ENSG00000183735 ENSG00000239732 ENSG00000163568 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC2754046__F1 Hypothetical schematic of a DAergic synapse ENSG00000123454 PMC6718713__F1 Microglial signaling pathways determining development of cells with divergent abilities ENSG00000242689 ENSG00000100906 ENSG00000137077 ENSG00000263528 ENSG00000086991 ENSG00000214285 PMC7782086__F8 Graphical abstract illustrates the function and regulatory mechanism of FOXD1‐AS1 in AGS ENSG00000124102 ENSG00000198793 ENSG00000121879 ENSG00000251493 PMC8381052__F4 Autoantibody-Specific Signalling in Pemphigus ENSG00000112851 ENSG00000134760 ENSG00000124181 ENSG00000108061 PMC8968138__F1 NTRK Fusion in Non-Small Cell Lung Cancer: Diagnosis, Therapy, and TRK Inhibitor Resistance ENSG00000002330 PMC7056923__F3 Lactate is a signaling molecule in cancer and endothelial cells ENSG00000101079 ENSG00000198793 ENSG00000146648 PMC8448164__F3 Mangifera indica (Mango): A Promising Medicinal Plant for Breast Cancer Therapy and Understanding Its Potential Mechanisms of Action ENSG00000002330 ENSG00000065361 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC8448164__F5 Mangifera indica (Mango): A Promising Medicinal Plant for Breast Cancer Therapy and Understanding Its Potential Mechanisms of Action ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8448164__F7 Mangifera indica (Mango): A Promising Medicinal Plant for Breast Cancer Therapy and Understanding Its Potential Mechanisms of Action ENSG00000198793 PMC7887252__F8 Proteins/enzymes in this pathway regulate both calcification and atherosclerosis ENSG00000197594 ENSG00000138185 PMC10572708__F12 Lipid and atherosclerosis metabolic pathway ENSG00000002330 ENSG00000170458 ENSG00000124370 ENSG00000183691 ENSG00000157625 ENSG00000007908 ENSG00000150455 ENSG00000119912 ENSG00000168610 ENSG00000164305 PMC3962153__F2 Products for which C PMC7835977__F6 Proposed mechanism by which GAT107 restores bacterial clearance in the lungs by reducing oxidative stress, due to hyperoxia ENSG00000079999 PMC8301062__F2 GSK-3B in Pancreatic Cancer: Spotlight on 9-ING-41, Its Therapeutic Potential and Immune Modulatory Properties ENSG00000175054 ENSG00000089692 PMC3404195__F6 Proposed regulatory mechanism of ERB in colitis-associated colon cancer ENSG00000111537 ENSG00000115415 ENSG00000168036 ENSG00000168610 ENSG00000293532 PMC12124727__F3 Metabolomic analysis in QFA of WT, db/db and Mpst−/− mice ENSG00000173599 PMC7438937__F5 Pathway enrichments of SHGS ENSG00000148584 ENSG00000236826 ENSG00000170860 ENSG00000130332 ENSG00000130520 ENSG00000160710 ENSG00000164167 ENSG00000114127 ENSG00000172795 PMC3313874__F2 Networks built using differentially expressed genes in uninfected macrophages from C57BL/6 and CBA mice ENSG00000134321 ENSG00000109861 ENSG00000119608 ENSG00000177674 ENSG00000243646 ENSG00000182985 ENSG00000170571 ENSG00000169715 ENSG00000130513 PMC2689781__F7 Grade-dependent Proteomics Characterization of Kidney Cancer ENSG00000074800 ENSG00000067057 ENSG00000248144 ENSG00000172340 ENSG00000136872 ENSG00000091140 PMC9497807__F4 Polycomb Directed Cell Fate Decisions in Development and Cancer ENSG00000108702 ENSG00000177575 ENSG00000134460 ENSG00000049768 ENSG00000169245 ENSG00000108691 ENSG00000111537 ENSG00000102970 ENSG00000107485 ENSG00000133961 ENSG00000283060 ENSG00000204520 ENSG00000106178 ENSG00000026103 PMC10341937__F2 Canonical Wnt signal transduction pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC9497807__F2 Polycomb Directed Cell Fate Decisions in Development and Cancer ENSG00000173894 ENSG00000108799 ENSG00000139154 ENSG00000273604 ENSG00000178691 ENSG00000008083 PMC4926062__F4 Deep sequencing and in silico analyses identify MYB-regulated gene networks and signaling pathways in pancreatic cancer ENSG00000017797 ENSG00000002330 ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000130649 ENSG00000171791 ENSG00000100985 PMC4926062__F2 Deep sequencing and in silico analyses identify MYB-regulated gene networks and signaling pathways in pancreatic cancer ENSG00000184220 ENSG00000149639 ENSG00000123136 ENSG00000162433 ENSG00000080345 ENSG00000136937 ENSG00000166479 ENSG00000077514 ENSG00000146143 ENSG00000198056 ENSG00000130935 ENSG00000168268 ENSG00000104756 ENSG00000174173 ENSG00000147536 ENSG00000136108 ENSG00000158234 ENSG00000092853 ENSG00000182963 ENSG00000121390 ENSG00000168938 ENSG00000110628 ENSG00000124193 ENSG00000118655 ENSG00000148943 ENSG00000171303 ENSG00000167702 ENSG00000101003 ENSG00000198554 ENSG00000029993 ENSG00000146648 ENSG00000130254 ENSG00000198355 ENSG00000112379 ENSG00000131153 ENSG00000188290 ENSG00000101596 ENSG00000164002 ENSG00000168461 ENSG00000183684 ENSG00000186871 ENSG00000147274 ENSG00000105223 ENSG00000115875 ENSG00000065328 ENSG00000197530 ENSG00000163811 ENSG00000100941 ENSG00000136527 ENSG00000149100 ENSG00000205364 ENSG00000087087 ENSG00000006016 ENSG00000165494 PMC6614175__F4 Antioxidant mechanism of the NRF2 pathway ENSG00000271303 ENSG00000007171 ENSG00000079999 PMC2976847__F1 Cytokines, hormones or growth factors that activate Stat5 ENSG00000002330 ENSG00000099985 ENSG00000173757 ENSG00000138798 PMC4826150__F1 Regulation of target genes by the Wnt/Beta-catenin asymmetry pathway ENSG00000204070 ENSG00000168036 PMC7437079__F3 STAT3 pathway and IL6/STAT3/S1PR1 amplification loop in IBD-CRC ENSG00000170989 ENSG00000168610 PMC5739082__F1 Simplified schematic depicting the mTOR pathway and associated “mTORopathies.” The mTOR pathway involves 2 complexes, mTORC1 and mTORC2 PMC7270529__F3 IPA’s individual pathway analysis of different proteins from the different experimental groups, linking them to a suggested promotion or inhibition of a cellular event under the umbrella of inhibition of cell death or change in cytoskeletal activity ENSG00000103266 ENSG00000125384 ENSG00000126457 ENSG00000150093 ENSG00000115310 ENSG00000073756 ENSG00000087460 ENSG00000089159 ENSG00000215021 ENSG00000154174 ENSG00000136997 ENSG00000173898 ENSG00000120438 ENSG00000275565 ENSG00000137948 ENSG00000123983 ENSG00000132341 ENSG00000062485 PMC4697282__F1 Chemical disruption of Wnt-dependent cell fate decision-making mechanisms in cancer and regenerative medicine ENSG00000116729 ENSG00000134569 ENSG00000134982 ENSG00000102312 ENSG00000168036 PMC4697282__F2 Chemical disruption of Wnt-dependent cell fate decision-making mechanisms in cancer and regenerative medicine ENSG00000116729 ENSG00000102312 ENSG00000173273 PMC5466605__F9 Illustration of a proposed signaling pathway of innate and adaptive immune activation in the Nx model (A) ENSG00000162711 ENSG00000167207 ENSG00000276561 ENSG00000150782 ENSG00000169245 ENSG00000239732 ENSG00000111537 ENSG00000170458 ENSG00000187554 ENSG00000177606 ENSG00000125538 ENSG00000136869 ENSG00000172936 ENSG00000175104 ENSG00000064012 ENSG00000184216 ENSG00000115594 PMC11980037__F5 Downregulation of Tnf, Il1a, and Il1b in M2c macrophages exhibited immune tolerance in autoimmune diseases ENSG00000134982 ENSG00000136869 ENSG00000103522 ENSG00000049768 PMC2676994__F1 Schematic model illustrating multiple signaling pathways in regulating StAR gene transcription ENSG00000138798 ENSG00000185591 PMC5593680__F3 Targeting metabolism and AMP-activated kinase with metformin to sensitize non-small cell lung cancer (NSCLC) to cytotoxic therapy: translational biology and rationale for current clinical trials ENSG00000149311 ENSG00000131473 ENSG00000198793 ENSG00000146648 ENSG00000026103 PMC4387772__F2 T Cell Energy Metabolism as a Controller of Cell Fate in Transplantation ENSG00000135218 ENSG00000163599 ENSG00000118520 PMC4387772__F1 T Cell Energy Metabolism as a Controller of Cell Fate in Transplantation ENSG00000122966 ENSG00000163599 ENSG00000150907 ENSG00000136997 ENSG00000049768 ENSG00000096717 PMC3193940__F2 An array of cellular stressors can perturb the folding environment in the endoplasmic reticulum (ER) leading to unfolded or misfolded protein ENSG00000159200 ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000171791 ENSG00000127191 PMC11980037__F3 KEGG disease pathways map analysis displays downregulated DEGs influenced by DEX-induced M2c macrophages involved in anti-allograft rejection ENSG00000111537 ENSG00000134982 PMC8281885__F2 Chemoresistance and Metastasis in Breast Cancer Molecular Mechanisms and Novel Clinical Strategies ENSG00000281324 ENSG00000162337 ENSG00000198793 ENSG00000168036 ENSG00000150457 ENSG00000128602 ENSG00000168610 ENSG00000131023 PMC3717802__F6 Superior efficacy of co-treatment with dual PI3K/mTOR inhibitor NVP-BEZ235 and pan-histone deacetylase inhibitor against human pancreatic cancer ENSG00000159224 ENSG00000106070 ENSG00000169047 PMC7657570__F1 Androgens facilitate SARS-COV2 entry through a TMPRSS2-mediated pathway ENSG00000130234 ENSG00000184012 PMC6817822__F9 PR55A regulatory subunit of PP2A inhibits the MOB1/LATS cascade and activates YAP in pancreatic cancer cells ENSG00000150457 ENSG00000131023 PMC8012676__F9 Proposed model for effect of GNE mutation on actin dynamics and cell migration ENSG00000159921 ENSG00000291971 PMC5627884__F9 Kyoto Encyclopedia of Genes and Genomes and TGFB signaling pathway with changes between adult facial fibroblasts and neonate fibroblasts denoted by color code ENSG00000049323 ENSG00000111537 ENSG00000095739 ENSG00000113558 ENSG00000156574 ENSG00000134363 PMC6547527__F8 a The Spearman correlation coefficient revealed the association between the changes of fermentation parameters and the expression of these eight growth-related genes (SCC > 0.85 and p < 0.01) ENSG00000002330 ENSG00000019549 ENSG00000091409 PMC7040073__F5 Changes in the transcript abundance of genes involved in central metabolic pathways, fatty acid biosynthesis, and the PKS-NRPS pathway ENSG00000074800 ENSG00000162882 ENSG00000026103 PMC2945394__F1 Post-pandrial increase in insulin leads to induction of lipogenesis and inhibition of lipolysis ENSG00000042832 PMC6540047__F3A Transcriptomic Analysis Reveals Priming of The Host Antiviral Interferon Signaling Pathway by Bronchobini® Resulting in Balanced Immune Response to Rhinovirus Infection in Mouse Lung Tissue Slices ENSG00000236637 ENSG00000188379 ENSG00000213928 ENSG00000250361 ENSG00000187608 ENSG00000137275 ENSG00000168040 ENSG00000181026 ENSG00000111537 ENSG00000088888 ENSG00000184995 ENSG00000142599 ENSG00000120235 ENSG00000131323 PMC8699551__F5 Molecular Signaling to Preserve Mitochondrial Integrity against Ischemic Stress in the Heart: Rescue or Remove Mitochondria in Danger ENSG00000177169 ENSG00000057663 PMC8699551__F3 Molecular Signaling to Preserve Mitochondrial Integrity against Ischemic Stress in the Heart: Rescue or Remove Mitochondria in Danger ENSG00000177169 ENSG00000156735 ENSG00000123240 ENSG00000204463 ENSG00000158828 ENSG00000151929 ENSG00000171791 ENSG00000166278 ENSG00000142082 ENSG00000183735 ENSG00000188554 ENSG00000116688 ENSG00000112208 PMC8924168__F5 BRCA1 mutations in high-grade serous ovarian cancer are associated with proteomic changes in DNA repair, splicing, transcription regulation and signaling ENSG00000104812 ENSG00000167258 ENSG00000182774 ENSG00000002330 ENSG00000172613 ENSG00000196504 ENSG00000198793 ENSG00000039650 ENSG00000178209 ENSG00000089157 ENSG00000169710 ENSG00000037474 ENSG00000141564 ENSG00000076003 ENSG00000139218 ENSG00000012048 ENSG00000175634 ENSG00000153046 ENSG00000177600 ENSG00000140464 ENSG00000173575 ENSG00000095787 ENSG00000143569 ENSG00000124193 ENSG00000160691 ENSG00000115875 ENSG00000067066 ENSG00000149136 ENSG00000061273 ENSG00000163166 ENSG00000100813 ENSG00000139154 ENSG00000054118 ENSG00000079435 ENSG00000087087 ENSG00000156273 PMC8236093__F1 Lipid-Derived Mediators are Pivotal to Leukocyte and Lung Cell Responses in Sepsis and ARDS ENSG00000170775 ENSG00000133067 ENSG00000171049 PMC6712069__F1 An overview of Wnt signaling pathway ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000163914 ENSG00000177606 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000168646 PMC4881503__F1 EPO-induced intracellular signaling pathways Erythropoietin and its receptor signaling through JAK2 activate multiple downstream signaling molecules including STAT5, PI3K/Akt, NFKB, and MAPK ENSG00000002330 ENSG00000187266 PMC6459341__F7 HIGH expression of OSM and IL-6 are associated with decreased breast cancer survival: synergistic induction of IL-6 secretion by OSM and IL-1B ENSG00000099985 ENSG00000125538 ENSG00000168610 ENSG00000115594 PMC3920756__F6 Single Nucleotide Polymorphisms in MicroRNA Binding Sites of Oncogenes: Implications in Cancer and Pharmacogenomics ENSG00000134982 ENSG00000172005 PMC5763539__F3 Pathway map for “LRRK2 and immune function in Parkinson’s disease” ENSG00000203747 ENSG00000140575 ENSG00000108671 PMC7853124__F1 Immunopathobiology and therapeutic targets related to cytokines in liver diseases ENSG00000100385 ENSG00000134460 ENSG00000096996 ENSG00000138378 ENSG00000115415 ENSG00000163739 ENSG00000138755 PMC4587736__F1 Germinal Center Kinases SmKIN3 and SmKIN24 Are Associated with the Sordaria macrospora Striatin-Interacting Phosphatase and Kinase (STRIPAK) Complex ENSG00000143093 ENSG00000128578 ENSG00000131023 ENSG00000291442 ENSG00000115540 PMC7953864__F6 Signaling pathway of MBHD-VD PPI network (blue and pink circles stand for compound target and VP genes, resp; red diamond stands for pathway; green hexagon stands for herb) ENSG00000226275 ENSG00000110395 ENSG00000291971 ENSG00000130522 ENSG00000198793 ENSG00000128052 ENSG00000177606 ENSG00000026103 PMC8211386__F2 Cancer therapeutic approaches targeting apoptosis pathways ENSG00000128272 ENSG00000002330 ENSG00000168040 ENSG00000125656 ENSG00000149295 PMC8211386__F1 Apoptosis signaling pathways and pro-survival, immune, or tumor microenvironment influences that impact on them ENSG00000149311 ENSG00000175054 ENSG00000128272 ENSG00000137275 ENSG00000163599 ENSG00000198793 ENSG00000136997 ENSG00000120868 ENSG00000171791 ENSG00000168040 PMC5763539__F4 Pathway map for “Inhibitory PD-1 signaling in T cells” ENSG00000145604 ENSG00000198793 ENSG00000123374 ENSG00000127948 ENSG00000141968 PMC9220155__F3 Multi-Target Effects of ß-Caryophyllene and Carnosic Acid at the Crossroads of Mitochondrial Dysfunction and Neurodegeneration: From Oxidative Stress to Microglia-Mediated Neuroinflammation ENSG00000162711 ENSG00000239732 ENSG00000164430 ENSG00000172216 ENSG00000158828 ENSG00000136869 ENSG00000079999 PMC9448813__F2 Notch signaling pathway ENSG00000114315 ENSG00000137845 PMC9957752__F13 Hepatocyte Smoothened Activity Controls Susceptibility to Insulin Resistance and Nonalcoholic Fatty Liver Disease ENSG00000164161 ENSG00000150907 ENSG00000169047 ENSG00000128602 PMC9220155__F4 Multi-Target Effects of ß-Caryophyllene and Carnosic Acid at the Crossroads of Mitochondrial Dysfunction and Neurodegeneration: From Oxidative Stress to Microglia-Mediated Neuroinflammation ENSG00000162711 ENSG00000239732 ENSG00000164430 ENSG00000181019 ENSG00000168610 ENSG00000079999 PMC6893479__F2 A summary of the main enzymes involved in the classic and alternative bile acid biosynthesis pathways ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC5411790__F1 Postulated interaction between enzastaurin and erlotinib in the EGFR pathway ENSG00000002330 ENSG00000198793 PMC5004872__F7 Schematic showing proposed mechanism of ECM synthesis following CDH11 engagement ENSG00000140937 ENSG00000163914 ENSG00000141052 PMC6195642__F1 AKT/mTOR Signalling Pathway ENSG00000095585 ENSG00000105369 ENSG00000117525 ENSG00000007312 ENSG00000150907 ENSG00000186716 ENSG00000198793 ENSG00000169047 ENSG00000010671 PMC8624812__F3 Probiotics Regulating Inflammation via NLRP3 Inflammasome Modulation: A Potential Therapeutic Approach for COVID-19 ENSG00000278718 ENSG00000162711 ENSG00000130234 ENSG00000125538 ENSG00000184012 PMC3089878__F2 Cholesterol transport in the CNS ENSG00000130164 ENSG00000173599 PMC5626616__F1 TNF-receptor superfamily agonists as molecular adjuvants for cancer vaccines ENSG00000139193 ENSG00000134982 ENSG00000171791 ENSG00000049768 PMC3262099__F8 The host cell EGF signaling pathway and proteins downstream of the EGF receptor that are activated in response to C ENSG00000291971 ENSG00000146648 PMC8252888__F9 GEFT Inhibits Autophagy and Apoptosis in Rhabdomyosarcoma via Activation of the Rac1/Cdc42-mTOR Signaling Pathway ENSG00000070831 ENSG00000198793 PMC7057844__F2 Molecular Mechanism of Runx2-Dependent Bone Development ENSG00000066468 ENSG00000291837 PMC9436900__F4 PI3K/AKT signalling pathway in inflammation, cell death and glial scar formation after traumatic spinal cord injury: Mechanisms and therapeutic opportunities ENSG00000002330 ENSG00000136869 PMC9436900__F2 PI3K/AKT signalling pathway in inflammation, cell death and glial scar formation after traumatic spinal cord injury: Mechanisms and therapeutic opportunities ENSG00000177169 ENSG00000083290 ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC12056481__F4 DUBs in Wnt/Beta-catenin pathway, MYC signaling pathway and Hippo pathway in HNSCC ENSG00000124422 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000131023 PMC5384738__F4 Top networks and gene connections.Notes: Literature-based clustering of differentially expressed genes using Ingenuity Pathway Analysis (IPA) after 78 hours of 100 µM corilagin stimulation in SKOV3 cells ENSG00000142192 ENSG00000277263 ENSG00000146648 PMC10474083__F1 Detailed kinetic model of glycolysis in Plasmodium falciparum-infected red blood cells for antimalarial drug target identification ENSG00000163064 ENSG00000164778 PMC12056481__F3 DUBs in the PI3K, TGFB and HIF-1A signaling pathway in HNSCC ENSG00000134086 ENSG00000198793 ENSG00000162607 ENSG00000169914 ENSG00000083799 PMC12056481__F2 DUBs in the p53 pathway, NFKB signaling pathway and RAS/RAF/MEK/ERK pathway in HNSCC ENSG00000048028 ENSG00000083799 ENSG00000146648 PMC11828970__F2 Simplified pathways of ammonia metabolism and treatment ENSG00000036473 PMC5864929__F4 Arachidonic Acid Metabolism Pathway ENSG00000226275 ENSG00000196839 ENSG00000172005 ENSG00000095303 ENSG00000148344 ENSG00000179593 ENSG00000275565 PMC7355739__F2 Modeling of the multiple functions of Reelin during migration, dendritic growth and synaptic development and the corresponding signaling pathways: (A,A’) ENSG00000274211 ENSG00000177707 ENSG00000110400 ENSG00000070831 ENSG00000174013 ENSG00000198793 ENSG00000155974 ENSG00000132639 ENSG00000173406 ENSG00000292366 PMC10516898__F15 Mechanism of D-TT-BMSCs inhibiting ferroptosis to repair the wound ENSG00000138449 ENSG00000151012 ENSG00000167468 ENSG00000167996 ENSG00000156273 PMC7986854__F7 MHC I antigen presentation pathway is down-regulated by multiple mechanisms in cancers ENSG00000157837 ENSG00000176624 PMC5031610__F2 Current knowledge on the cell type/context-dependent regulation of Wnt/Beta-catenin signaling by NFKB pathway ENSG00000138795 ENSG00000134982 PMC5306062__F2 Cell death induced by benzopyran compounds by minor chemical modifications of the benzopyran scaffold ENSG00000198793 PMC5031610__F1 Current knowledge on the cell type/context-dependent regulation of NFKB signaling by Wnt/Beta-catenin pathway ENSG00000166167 ENSG00000134982 ENSG00000136869 ENSG00000127863 PMC4630557__F2 Signaling pathways of main checkpoints molecules ENSG00000291603 ENSG00000134982 ENSG00000198793 PMC4401268__F1A Dual role of Cav-1 Y14 phosphorylation: phosphorylat-ed caveolin (pYCav-1) is involved in the control of integrin-mediated signal transduction and caveolae-mediated cholesterol-enriched membrane microdomains (CEMM) endocy-tosis ENSG00000291971 ENSG00000163914 PMC4801467__F1 Mechanisms and immunotherapeutic targets for glioblastoma (GBM) ENSG00000183735 ENSG00000049768 ENSG00000276561 ENSG00000106546 PMC8199574__F3 Catecholaldehyde Hypothesis for the Pathogenesis of Catecholaminergic Neurodegeneration: What We Know and What We Do Not Know ENSG00000123454 PMC4322971__F3 Role of p53 in the progression of gastric cancer ENSG00000145321 PMC8301030__F10 Current Perspectives on the Beneficial Effects of Soybean Isoflavones and Their Metabolites for Humans ENSG00000145321 ENSG00000131196 ENSG00000143387 PMC6657254__F1 Summary of the neuroprotective action of resveratrol ENSG00000096717 PMC7990077__F5 Proposed mechanistic diagram of the multi-faceted, anti-neoplastic effects of GSE against lung cancer ENSG00000197081 ENSG00000124212 PMC5864729__F6 Schematic summary of mechanisms underlying VRCZ-induced skin cancer ENSG00000140465 ENSG00000106546 PMC12202337__F3 The ERK signaling pathway in regulating remyelination ENSG00000242689 PMC8946840__F2 Mesothelin: An Immunotherapeutic Target beyond Solid Tumors ENSG00000002330 ENSG00000123374 ENSG00000102854 ENSG00000168610 PMC6042636__F2 Sox2: regulation of expression and contribution to brain tumors ENSG00000136535 ENSG00000134982 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC5702855__F2 Multiple signaling pathways drive EMT in GBC cells ENSG00000156076 ENSG00000134982 ENSG00000198793 ENSG00000272398 ENSG00000026508 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC2211634__F3 Models for the dual roles of KLF4 and KLF5 in tumor suppression and oncogenesis ENSG00000136826 PMC9220225__F2 2-Hydroxyglutarate in Acute Myeloid Leukemia: A Journey from Pathogenesis to Therapies ENSG00000134086 ENSG00000155792 ENSG00000066135 PMC6407321__F4 Protection for oral SUB+IV vaccine against tick infestations in cattle ENSG00000125538 PMC11387120__F3 Drug resistance mechanism of tumor immune microenvironment factors ENSG00000102962 ENSG00000108700 ENSG00000168610 PMC7779537__F8 Aberrant elevation of GDF8 impairs granulosa cell glucose metabolism via upregulating SERPINE1 expression in patients with PCOS PMC4185425__F3 The Programmed Death-1 Immune Suppressive Pathway: Barrier to Anti-Tumor Immunity ENSG00000134982 ENSG00000163599 PMC2613471__F1 Revisiting Notch in remyelination of multiple sclerosis lesions ENSG00000117525 ENSG00000148400 PMC10604135__F6 Mutated proteins in four patients colored with red, green, cyan, and brown with arrangements of their roles on Wnt and mTOR signaling pathways ENSG00000156076 ENSG00000165359 ENSG00000144455 ENSG00000168036 PMC8698499__F12 Novel Insights into the Prognosis and Immunological Value of the SLC35A (Solute Carrier 35A) Family Genes in Human Breast Cancer ENSG00000145604 ENSG00000068028 ENSG00000149311 ENSG00000175054 ENSG00000094804 ENSG00000110514 ENSG00000134982 ENSG00000100219 ENSG00000166851 ENSG00000117399 PMC4185425__F1 Programmed Death-1 Immune Suppressive Pathway: Barrier to Anti-Tumor Immunity ENSG00000291603 ENSG00000134982 ENSG00000163599 ENSG00000173599 PMC4158833__F4 Shaping the mammalian auditory sensory organ by the planar cell polarity pathway ENSG00000107404 ENSG00000112655 PMC5187940__F3 Effect of Pb on the signaling pathway TLR4-MyD88-NFKB and the production of pro-inflammatory cytokines in microglial cells ENSG00000177606 ENSG00000172936 ENSG00000175104 PMC5136547__F1 Innate immune response against rotavirus in intestinal epithelial cells (IECs) ENSG00000169245 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000177606 ENSG00000131323 ENSG00000135828 ENSG00000175104 ENSG00000164342 PMC6891791__F4 Deciphering Molecular Mechanism of the Neuropharmacological Action of Fucosterol ENSG00000090402 ENSG00000111837 ENSG00000198793 ENSG00000171759 PMC3677900__F5 Deguelin Action Involves c-Met and EGFR Signaling Pathways in Triple Negative Breast Cancer Cells ENSG00000019991 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC6891791__F6 Immune system pathways in KEGG pathway analysis ENSG00000167653 ENSG00000168040 ENSG00000164305 ENSG00000026103 PMC6891791__F5 Nervous system pathways in KEGG pathway analysis ENSG00000162889 ENSG00000142192 ENSG00000100906 ENSG00000169047 ENSG00000177606 ENSG00000087085 ENSG00000173039 PMC9465410__F4 Exploring the mechanism of YangXue QingNao Wan based on network pharmacology in the treatment of Alzheimer’s disease ENSG00000142192 PMC7395405__F4 Schematic diagram of signaling pathways in exosome-mediated autophagy inside target cell ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC9019277__F1 Teaching an old dog new tricks: reactivated developmental signaling pathways regulate ABCB1 and chemoresistance in cancer ENSG00000164093 ENSG00000128602 PMC7084677__F1 Canonical phosphatase and tensin homolog (PTEN)-induced kinase 1 (PINK1)/Parkin pathway ENSG00000110497 ENSG00000175193 ENSG00000158828 PMC5837509__F2 Apoptosis and p53 signaling related to Cr(VI) exposure ENSG00000149311 ENSG00000002330 ENSG00000067900 ENSG00000171791 ENSG00000148935 ENSG00000084774 ENSG00000115317 PMC3919568__F7 Integrated metabolic pathway of BCAA metabolism ENSG00000138029 ENSG00000124370 ENSG00000078070 ENSG00000103150 ENSG00000103257 ENSG00000131844 ENSG00000127884 ENSG00000117054 ENSG00000175198 ENSG00000198754 ENSG00000137992 ENSG00000114054 ENSG00000083720 ENSG00000075239 ENSG00000105552 ENSG00000091140 ENSG00000117305 PMC3095763__F1 Toll-like receptor Signaling in Neural Plasticity and Disease ENSG00000170458 ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000100985 PMC9526834__F1 Dietary Patterns and Gut Microbiota: The Crucial Actors in Inflammatory Bowel Disease ENSG00000198793 ENSG00000168404 PMC4783780__F8 Response of Human Osteoblast to n-HA/PEEK—Quantitative Proteomic Study of Bio-effects of Nano-Hydroxyapatite Composite ENSG00000182901 ENSG00000189433 ENSG00000288435 ENSG00000118729 ENSG00000169562 ENSG00000134308 ENSG00000176533 ENSG00000174021 ENSG00000158445 ENSG00000196531 ENSG00000150681 ENSG00000148908 ENSG00000091844 ENSG00000184304 ENSG00000114450 ENSG00000090104 ENSG00000170027 ENSG00000078369 ENSG00000116741 ENSG00000117152 ENSG00000166278 ENSG00000043591 ENSG00000137731 ENSG00000188910 ENSG00000169220 ENSG00000067191 ENSG00000127588 ENSG00000162104 ENSG00000135549 ENSG00000152661 ENSG00000149782 ENSG00000123104 ENSG00000133019 ENSG00000198838 ENSG00000143333 ENSG00000121742 ENSG00000162188 ENSG00000167414 ENSG00000127928 ENSG00000172380 ENSG00000175793 ENSG00000081248 ENSG00000198626 ENSG00000143933 ENSG00000171033 ENSG00000187513 ENSG00000148660 ENSG00000141480 ENSG00000167535 ENSG00000145349 ENSG00000186469 PMC10252624__F1 Mechanisms of VEGF (receptor) inhibitors-induced cardiovascular complications ENSG00000112715 ENSG00000150630 PMC11854354__F2 Signaling cascades generalized for ubiquitin-mediated IKK activation in IL-1R/TLR and TNF pathways ENSG00000123240 ENSG00000102871 ENSG00000172936 ENSG00000157625 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC3210079__F8 Jagged1 functions downstream of Twist1 in the specification of the coronal suture and the formation of a boundary between osteogenic and non-osteogenic cells ENSG00000170365 ENSG00000122691 ENSG00000116106 ENSG00000168036 ENSG00000114315 PMC10239259__F2 Association Between Sarcopenia and Diabetes: From Pathophysiology Mechanism to Therapeutic Strategy ENSG00000169047 ENSG00000198793 ENSG00000164483 ENSG00000163884 ENSG00000123124 PMC10252624__F2 Primary mechanisms of ICIs-associated cardiotoxicity ENSG00000134982 ENSG00000163599 PMC11854354__F3 Ubiquitin-mediated IKK activation and Bcl10 autophagy in the T cell signaling pathway ENSG00000291603 PMC3830939__F2 Tudor: a versatile family of histone methylation ‘readers’ ENSG00000149311 ENSG00000101751 ENSG00000119403 ENSG00000176476 ENSG00000074266 ENSG00000178691 ENSG00000166169 ENSG00000276043 PMC9843448__F1 Angiogenesis in hepatocellular carcinoma: mechanisms and anti-angiogenic therapies ENSG00000170365 ENSG00000107562 ENSG00000124766 ENSG00000176046 ENSG00000112715 ENSG00000077782 ENSG00000168610 ENSG00000121966 ENSG00000197461 PMC11500076__F2 STING signaling in dendritic cells (DCs) ENSG00000164430 PMC6770861__F6 A Novel Tanshinone Analog Exerts Anti-Cancer Effects in Prostate Cancer by Inducing Cell Apoptosis, Arresting Cell Cycle at G2 Phase and Blocking Metastatic Ability ENSG00000134057 ENSG00000100985 ENSG00000166851 PMC11481725__F2 Protective role of brown adipose tissue in cardiac cell damage after myocardial infarction and heart failure ENSG00000087245 ENSG00000105550 ENSG00000100985 PMC11481725__F1 Protective role of brown adipose tissue in cardiac cell damage after myocardial infarction and heart failure ENSG00000170365 ENSG00000105550 PMC11500076__F1 STING signaling pathway ENSG00000183735 ENSG00000164430 PMC5361499__F1 Amyloid precursor protein (APP) processing.APP preferred processing is the non-amyloidogenic pathway which digests with Alpha-secretase followed Gamma-secretase and takes place at the plasma membrane (PM) ENSG00000120885 ENSG00000073921 ENSG00000137642 PMC6175949__F8 Proposed positive feedback mechanism for Th17 cell-secreted IL-17A and NLRP3 inflammasome activity in a circuit ENSG00000162711 ENSG00000125538 ENSG00000091592 PMC7452966__F1 Amino acid metabolism in pluripotency regulation ENSG00000128272 ENSG00000144895 ENSG00000135069 ENSG00000178445 PMC6560007__F1 MicroRNA biogenesis ENSG00000128191 ENSG00000113360 PMC6962107__F2 L-ornithine biosynthesis metabolic pathways in C ENSG00000150787 PMC3694398__F5 NFAT Gene Family in Inflammation and Cancer ENSG00000168036 ENSG00000113520 ENSG00000131196 PMC4246949__F9 Scheme of the regulatory interactions connecting PREP1 and PBX1 expression with the TGFB–SMAD3 pathway, cellular invasion, and EMT ENSG00000177606 PMC6914882__F10 Schematic representation influence of PCr against DCM on Bcl-2 family members and other mitochondrial apoptotic and metabolic proteins in cardiomyocytes under various pathological conditions ENSG00000132906 ENSG00000171791 ENSG00000168610 ENSG00000164305 PMC5053108__F7 Role of miR-9 in zebrafish brain development.Notes: (A) Zebrafish forebrain: In the forebrain, miR-9 inhibits proneural gene her6 and targets Fgf signaling pathway genes (dusp6, pea3) ENSG00000196361 ENSG00000077782 ENSG00000139800 PMC8185021__F6 Cleavage of Syndecan-1 Promotes the Proliferation of the Basal-Like Breast Cancer Cell Line BT-549 Via Akt SUMOylation ENSG00000087245 ENSG00000115884 ENSG00000157227 ENSG00000100985 ENSG00000062485 PMC4598091__F1 Exclusive Association of p53 Mutation with Super-High Methylation of Tumor Suppressor Genes in the p53 Pathway in a Unique Gastric Cancer Phenotype ENSG00000112977 ENSG00000171476 PMC2743241__F1 Hedgehog-Gli Signaling Pathway Inhibitors as Anticancer Agents ENSG00000106571 ENSG00000143839 ENSG00000128602 ENSG00000127334 PMC5751802__F3 Signaling pathways corresponding to Tables  and ENSG00000149311 ENSG00000117399 PMC8639975__F4 Genomics and transcriptomics landscapes associated to changes in insulin sensitivity in response to endurance exercise training ENSG00000041982 ENSG00000148660 ENSG00000087085 PMC8990433__F1 Cholesterol metabolism and its implication in glioblastoma therapy ENSG00000130164 ENSG00000291971 ENSG00000198492 ENSG00000036530 ENSG00000113161 ENSG00000146648 ENSG00000026103 PMC4058364__F7 HRG-mediated signaling via mTORC2 to mTORC1 ENSG00000113905 ENSG00000065361 ENSG00000178568 PMC7859793__F5 Protein-protein interaction (PPI) analysis of differentially expressed alternative splicing (DEAS) events ENSG00000132694 ENSG00000275111 ENSG00000155755 ENSG00000135451 ENSG00000090989 ENSG00000110931 ENSG00000178449 ENSG00000166484 ENSG00000185010 ENSG00000136002 ENSG00000137807 ENSG00000177595 ENSG00000038427 ENSG00000139613 ENSG00000163681 ENSG00000196498 ENSG00000182667 ENSG00000171105 ENSG00000157216 ENSG00000142192 ENSG00000092853 ENSG00000213390 ENSG00000198561 ENSG00000162520 ENSG00000073921 ENSG00000087460 ENSG00000123219 ENSG00000117650 ENSG00000110841 ENSG00000157766 ENSG00000026508 ENSG00000133961 ENSG00000105426 ENSG00000149554 PMC8660802__F2 Biogenesis and release of exosomes ENSG00000276051 ENSG00000074319 ENSG00000110651 ENSG00000010278 ENSG00000135404 PMC4199550__F3 Iron Necessity: The Secret of Wolbachia's Success? ENSG00000144410 ENSG00000126088 ENSG00000188690 PMC5727308__F1 WNT signalling pathways ENSG00000169071 ENSG00000100592 ENSG00000134982 ENSG00000185483 ENSG00000168036 PMC7579760__F3 Hepatitis C virus life cycle ENSG00000130164 ENSG00000163914 ENSG00000110651 ENSG00000146648 PMC8670090__F1 Therapeutic Targeting of Autophagy in Pancreatic Ductal Adenocarcinoma ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000126775 ENSG00000144848 ENSG00000171791 ENSG00000145782 ENSG00000057663 PMC9019160__F1 Targeting the PI3K/AKT/mTOR pathway in epithelial ovarian cancer, therapeutic treatment options for platinum-resistant ovarian cancer ENSG00000149311 ENSG00000132906 ENSG00000175054 ENSG00000002330 ENSG00000005882 PMC5138061__F1 Schematic representation of hypothesized cholesterol/phospholipid recycling mechanisms in the injured CNS ENSG00000130164 PMC8712284__F4 Modular control of multiple pathways of Corynebacterium glutamicum for 5-aminolevulinic acid production ENSG00000069482 ENSG00000198576 PMC5662062__F4 Replication Stress Response in Mammals and Trypanosomatids ENSG00000175054 ENSG00000164053 ENSG00000113456 PMC6325765__F6 Central carbon and Gamma-PGA production pathways ENSG00000197713 ENSG00000122966 ENSG00000172005 ENSG00000062485 PMC8395475__F2 Adipose Tissue Dendritic Cells: Critical Regulators of Obesity-Induced Inflammation and Insulin Resistance ENSG00000262406 ENSG00000111537 PMC12109257__F6 MicroRNAs in oral cancer progression ENSG00000136997 ENSG00000146648 ENSG00000128191 ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC6013441__F4 STRING pathway analysis of up- and downregulated genes in MDA-MB-231 cells co-cultured with adipocytes ENSG00000159167 ENSG00000081041 ENSG00000108551 ENSG00000170848 ENSG00000170373 ENSG00000111341 ENSG00000164400 ENSG00000288292 ENSG00000283060 ENSG00000073756 ENSG00000162892 ENSG00000130513 PMC10489936__F4 Polysaccharides modulate liver bile acids (BAs)-related signaling pathways of metabolic associated fatty liver disease (MAFLD) ENSG00000160867 ENSG00000026103 PMC7255470__F7 Schematic representation shows the potential mechanism of Sevo-mediated anti-proliferation and anti-invasion roles in hepatocellular carcinoma cells ENSG00000168036 PMC7487481__F5 Metabolites, major metabolic pathways and pathway-related enzyme changes in palm oil-grown ENSG00000122966 ENSG00000123505 PMC7612806__F1 Simplified schematic of the KYN pathway PMC8358664__F2 P53 Family: A Role in Lipid and Iron Metabolism ENSG00000131473 ENSG00000169710 ENSG00000103150 ENSG00000026103 PMC7745315__F6 Expression of the NEK7/NLRP3 inflammasome pathway in patients with diabetic lower extremity arterial disease ENSG00000162711 PMC12084451__F7 The differentiation paths of gastric epithelial cells and signaling regulation ENSG00000291363 ENSG00000186009 ENSG00000160685 ENSG00000138798 ENSG00000184956 ENSG00000100219 ENSG00000089199 PMC4786305__F2 The Herpes Simplex Virus Neurovirulence Factor G34.5: Revealing Virus–Host Interactions ENSG00000213928 ENSG00000144895 ENSG00000115415 PMC5500819__F1 Schematic depiction of the strategy employed for mining the O-Man glycoproteome in cell lines with knock-out of COSMC, POMGNT1, POMT1, and POMT2 ENSG00000144647 ENSG00000152127 ENSG00000009830 ENSG00000130714 PMC9281180__F2 Spotlight on pyroptosis: role in pathogenesis and therapeutic potential of ocular diseases ENSG00000278718 ENSG00000162711 ENSG00000137275 ENSG00000167914 ENSG00000145649 ENSG00000157625 ENSG00000136869 ENSG00000175104 ENSG00000147697 ENSG00000184216 ENSG00000073605 PMC9281180__F4 Spotlight on pyroptosis: role in pathogenesis and therapeutic potential of ocular diseases ENSG00000162711 ENSG00000197713 ENSG00000135218 ENSG00000086991 ENSG00000100697 ENSG00000172936 ENSG00000184216 PMC8804176__F2 Depression, Estrogens, and Neuroinflammation: A Preclinical Review of Ketamine Treatment for Mood Disorders in Women ENSG00000136869 PMC9281180__F3 Spotlight on pyroptosis: role in pathogenesis and therapeutic potential of ocular diseases ENSG00000278718 ENSG00000162711 ENSG00000197713 ENSG00000265972 ENSG00000165819 PMC8777261__F4 Proteomic analysis of metabolic pathways supports chloroplast–mitochondria cross‐talk in a Cu‐limited diatom ENSG00000173599 PMC11202538__F1 Canonical Shh signalling pathway ENSG00000166813 ENSG00000164690 ENSG00000128602 PMC6409697__F9 rLj-112 was internalized with EGFR to suppress the downstream signaling pathways to initiate the anti-tumor steps in B16 cells ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC4105535__F4 Molecular Changes in Pre-Metastatic Lymph Nodes of Esophageal Cancer Patients ENSG00000012048 ENSG00000138795 ENSG00000177606 ENSG00000136997 ENSG00000185591 ENSG00000139687 PMC4689162__F1 Beclin-1 interaction complexes Atg14L and UVRAG/Bif-1 activate the Beclin-1 complexes and induce the formation of autophagosomes in a mutually exclusive manner ENSG00000110497 ENSG00000198382 ENSG00000189403 ENSG00000175104 ENSG00000062716 PMC11202538__F3 Targeting the Shh signalling pathway regulators ENSG00000164690 ENSG00000128602 PMC11202538__F2 Crosstalk with the Shh signalling pathway ENSG00000134982 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC8245914__F10 HYD-PEP06 suppresses hepatocellular carcinoma metastasis, epithelial–mesenchymal transition and cancer stem cell-like properties by inhibiting PI3K/AKT and WNT/Beta-catenin signaling activation ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC10372646__F1 Pomegranate-specific natural compounds as onco-preventive and onco-therapeutic compounds: Comparison with conventional drugs acting on the same molecular mechanisms ENSG00000138798 ENSG00000164690 PMC9221433__F7 Targeting Acid Ceramidase Inhibits Glioblastoma Cell Migration through Decreased AKT Signaling ENSG00000140992 ENSG00000177169 ENSG00000168209 ENSG00000171105 ENSG00000119487 ENSG00000198793 ENSG00000149091 ENSG00000164327 ENSG00000141564 ENSG00000167965 ENSG00000187840 ENSG00000163914 ENSG00000173599 ENSG00000204673 PMC4689162__F3 Autophagy and some of its regulatory pathways Binding of insulin or growth factors to the insulin receptor triggers the PI3K pathway, converting PIP2 into PIP3 that recruits PDK1 and Akt to the plasma membrane ENSG00000169047 ENSG00000145782 ENSG00000057663 PMC5136547__F4 Beneficial effects of immunobiotic bifidobacteria on the innate immune response against rotavirus in intestinal epithelial cells (IECs) ENSG00000169245 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000177606 ENSG00000131323 ENSG00000135828 ENSG00000175104 ENSG00000164342 PMC6110855__F1 Phenotype change of microglia in neurodegenerative disorders ENSG00000177575 ENSG00000125538 ENSG00000118520 ENSG00000213523 PMC6892558__F4 East-Asian Helicobacter pylori strains synthesize heptan-deficient lipopolysaccharide ENSG00000038382 ENSG00000069482 ENSG00000088926 PMC4600211__F2 Pathway Express analysis of the host response to IBV infection in the trachea of susceptible birds (Line 15I) ENSG00000232326 ENSG00000127022 ENSG00000273686 ENSG00000168040 ENSG00000150455 ENSG00000142224 ENSG00000143387 ENSG00000019582 ENSG00000239732 ENSG00000111537 ENSG00000144410 ENSG00000170458 ENSG00000163131 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 PMC5425374__F2 Hsp70 in signal transduction pathways ENSG00000175104 PMC4946416__F1 PI3K/PKB/mTOR signaling pathway regulates cancer cell metabolism ENSG00000198793 ENSG00000136997 ENSG00000169710 ENSG00000168036 ENSG00000196628 PMC8699194__F1 Insight into the Double-Edged Role of Ferroptosis in Disease ENSG00000168003 ENSG00000151012 ENSG00000197635 ENSG00000167468 ENSG00000122873 ENSG00000079999 PMC2939392__F2 Proposed inhibitory mechanisms of SOCS1 on TLR signaling ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC8268847__F3 MRNA Translation by Hormone Receptors in Breast and Prostate Cancer ENSG00000163435 ENSG00000144895 ENSG00000284161 ENSG00000137760 ENSG00000174177 ENSG00000142544 PMC5429724__F4 Intracellular levels of interleukins are related to circulating UCB and underlying molecular measures of heme catabolism ENSG00000132693 PMC5429724__F3 Graphical summary of inter-variable connections for the entire BiliHealth study population ENSG00000125538 ENSG00000132693 PMC9531511__F2 Emerging role of STING signalling in CNS injury: inflammation, autophagy, necroptosis, ferroptosis and pyroptosis ENSG00000177169 ENSG00000057663 PMC9531511__F1 Emerging role of STING signalling in CNS injury: inflammation, autophagy, necroptosis, ferroptosis and pyroptosis ENSG00000183735 ENSG00000164430 PMC9531511__F4 Emerging role of STING signalling in CNS injury: inflammation, autophagy, necroptosis, ferroptosis and pyroptosis ENSG00000183735 ENSG00000101751 ENSG00000164430 ENSG00000167468 PMC9531511__F3 Emerging role of STING signalling in CNS injury: inflammation, autophagy, necroptosis, ferroptosis and pyroptosis ENSG00000164430 ENSG00000137275 ENSG00000168404 ENSG00000285379 ENSG00000142166 PMC11562918__F3 HSV-1 mediates innate immune signalling and escape strategies ENSG00000162711 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000110395 ENSG00000163565 ENSG00000172936 ENSG00000091106 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC11756206__F4 Signaling pathways regulated by H ENSG00000134982 ENSG00000168036 ENSG00000146648 PMC11756206__F3 Aberrant Wnt/Beta-catenin, STAT3, and Hippo/YAP signaling pathways activation in H ENSG00000291971 ENSG00000163914 ENSG00000168036 ENSG00000168610 ENSG00000146648 ENSG00000131023 PMC9531511__F5 Emerging role of STING signalling in CNS injury: inflammation, autophagy, necroptosis, ferroptosis and pyroptosis ENSG00000278718 ENSG00000164430 ENSG00000163568 ENSG00000125538 PMC10297881__F13 Apoptosis and p53 signaling pathway in all analyzed groups ENSG00000149212 ENSG00000153094 ENSG00000099860 ENSG00000196470 ENSG00000171791 ENSG00000118971 ENSG00000285069 ENSG00000080546 ENSG00000137801 ENSG00000103811 ENSG00000109861 ENSG00000140379 ENSG00000089685 ENSG00000105810 ENSG00000263238 ENSG00000023445 ENSG00000104689 ENSG00000104365 ENSG00000116717 ENSG00000134574 ENSG00000163131 ENSG00000171848 ENSG00000075218 ENSG00000127824 ENSG00000171608 PMC11756206__F2 Development of gastric cancer is induced by H ENSG00000197905 ENSG00000168036 ENSG00000168610 PMC10297881__F12 Apoptosis and p53 signaling pathway in the control compared to adipocytes, chondrocytes, neural-like cells and osteoblasts ENSG00000023445 ENSG00000167553 ENSG00000104689 ENSG00000123416 ENSG00000153094 ENSG00000167552 ENSG00000196470 ENSG00000006062 ENSG00000285069 ENSG00000137801 ENSG00000143387 ENSG00000138764 ENSG00000140379 ENSG00000134057 ENSG00000163131 ENSG00000171848 ENSG00000136848 ENSG00000163554 ENSG00000075218 ENSG00000105810 ENSG00000127824 ENSG00000171608 ENSG00000149554 ENSG00000175305 PMC9550864__F2 Deregulated hyaluronan metabolism in the tumor microenvironment drives cancer inflammation and tumor-associated immune suppression ENSG00000026508 ENSG00000068001 PMC4537205__F5 Microarray and Proteomic Analyses of Myeloproliferative Neoplasms with a Highlight on the mTOR Signaling Pathway ENSG00000140992 ENSG00000168209 ENSG00000198793 ENSG00000169047 ENSG00000155876 ENSG00000281877 ENSG00000112715 ENSG00000132356 ENSG00000187840 ENSG00000161960 ENSG00000107581 ENSG00000175634 ENSG00000166501 ENSG00000135932 PMC4386371__F5 Model for the role of specific acyl-CoA oxidase homo- and heterodimers in the biosynthetic pathway of (omega-1)-ascarosides (A) and omega-ascarosides (B) ENSG00000039537 ENSG00000113600 ENSG00000161533 ENSG00000087008 PMC6504559__F7 Schema of possible mechanisms of action of MyD88−/− donor T cells during aGVHD ENSG00000137033 ENSG00000172936 PMC2408969__F8 Deciphering the Ubiquitin-Mediated Pathway in Apicomplexan Parasites: A Potential Strategy to Interfere with Parasite Virulence ENSG00000150991 ENSG00000100387 ENSG00000134982 ENSG00000113558 ENSG00000172005 ENSG00000117399 PMC9101511__F3 Retinitis Pigmentosa: Progress in Molecular Pathology and Biotherapeutical Strategies ENSG00000278718 ENSG00000177169 ENSG00000083290 ENSG00000102871 ENSG00000157625 ENSG00000255690 ENSG00000168040 PMC8944605__F3 MicroRNAs, Long Non-Coding RNAs, and Circular RNAs in the Redox Control of Cell Senescence ENSG00000168283 ENSG00000187531 ENSG00000117525 ENSG00000105835 ENSG00000285109 ENSG00000124523 ENSG00000077463 ENSG00000096717 ENSG00000142082 ENSG00000089163 ENSG00000283100 PMC6117394__F4 Biochemical mechanisms of oncometabolite accumulation ENSG00000100412 ENSG00000079999 PMC6117394__F3 Mitochondria at the crossroad of metabolic and signaling networks ENSG00000284320 ENSG00000131473 ENSG00000065911 ENSG00000135423 ENSG00000181788 ENSG00000198793 ENSG00000136997 ENSG00000169710 ENSG00000166278 ENSG00000062485 PMC5522055__F3 Actinidia chinensis Planch root extract inhibits cholesterol metabolism in hepatocellular carcinoma through upregulation of PCSK9 ENSG00000171105 ENSG00000130164 ENSG00000135100 ENSG00000159461 ENSG00000198793 ENSG00000113161 ENSG00000186480 ENSG00000169174 ENSG00000198911 PMC8101191__F2 Coordinated regulation of immune contexture: crosstalk between STAT3 and immune cells during breast cancer progression ENSG00000104856 ENSG00000166501 ENSG00000026508 ENSG00000137845 ENSG00000168610 ENSG00000196628 PMC9367163__F7 Combination of high glucose and LPS induces autophagy in bovine kidney epithelial cells via the Notch3/mTOR signaling pathway ENSG00000074181 ENSG00000198793 ENSG00000144848 PMC5706385__F6 Schematic model for ZJW extracts in inhibiting 5-HTR1D and attenuating Wnt/Beta-catenin signaling pathway ENSG00000004975 ENSG00000087245 ENSG00000138795 ENSG00000137673 ENSG00000162337 ENSG00000168036 ENSG00000161202 ENSG00000196628 PMC7349567__F1 Regulatory metabolic pathways of ferroptosis ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000197429 ENSG00000113161 ENSG00000115107 ENSG00000115419 PMC6194902__F1 Terpenoids biosynthesis pathway (A), and pathway engineering strategies (B,C) ENSG00000039537 ENSG00000197429 ENSG00000166278 PMC4405118__F1 A Sonic hedgehog (Shh) response deficit in trisomic cells may be a common denominator for multiple features of Down syndrome ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC6105016__F7 Investigating genetic-and-epigenetic networks, and the cellular mechanisms occurring in Epstein–Barr virus-infected human B lymphocytes via big data mining and genome-wide two-sided NGS data identification ENSG00000063978 ENSG00000030582 ENSG00000181852 ENSG00000075142 ENSG00000164587 ENSG00000197746 ENSG00000173039 ENSG00000057663 ENSG00000086065 ENSG00000180210 ENSG00000197256 ENSG00000157110 ENSG00000169750 ENSG00000177606 ENSG00000091844 ENSG00000117335 ENSG00000131323 ENSG00000284194 PMC4595346__F3 Connecting Myokines and Metabolism ENSG00000135414 PMC11670023__F1 Triggering receptor expressed on myeloid cells signaling pathway ENSG00000008438 ENSG00000162711 ENSG00000291603 ENSG00000187796 ENSG00000189403 ENSG00000172936 ENSG00000100985 ENSG00000204936 ENSG00000175104 ENSG00000184216 PMC4497387__F1 Radiation-induced acetylated and deacetylated proteins ENSG00000168028 ENSG00000291931 ENSG00000181163 ENSG00000197958 ENSG00000213741 ENSG00000083312 ENSG00000278270 ENSG00000112306 PMC8348158__F8 Transcriptomic and Metabolic Network Analysis of Metabolic Reprogramming and IGF-1 Modulation in SCA3 Transgenic Mice ENSG00000112964 ENSG00000278316 ENSG00000140443 PMC8799879__F1 Symphony of nanomaterials and immunotherapy based on the cancer–immunity cycle ENSG00000026103 PMC7279373__F1 Interplay between reactive oxygen species (ROS) and the central carbon metabolism ENSG00000065833 PMC6678695__F7 Scheme of autophagic cell death induced by the combination of Oxaliplatin and DHA ENSG00000128272 ENSG00000144895 ENSG00000285069 PMC4805512__F1 TNFR1-driven pathway ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC6336165__F2 Theory for polymicrogyria and brain arteriovenous malformations in HHT ENSG00000128917 ENSG00000112715 ENSG00000163217 PMC7395594__F2 Nrf2-ARE and Wnt/Beta-catenin/GSK-3B intertwined signaling cascades ENSG00000178573 ENSG00000134982 ENSG00000079999 PMC3096496__F6 Model depicting the generation and consequences of ROS-mediated base damage ENSG00000292286 ENSG00000129071 ENSG00000140398 PMC7501057__F7 Intercellular fibrin networks prevent erythrocyte leakage ENSG00000084093 ENSG00000162692 ENSG00000122194 PMC3580432__F2 Possible key signaling components in the force-mediated stem cell differentiation ENSG00000164828 ENSG00000198670 PMC7985188__F1 Data, methods (a) and results (b) for TBNC network identification (A) Workflow of the proposed computational approach ENSG00000012048 PMC9210594__F2 Potential fate decision landscape of the TWEAK/Fn14 axis on stem and progenitor cells: a systematic review ENSG00000009709 ENSG00000019991 ENSG00000168283 ENSG00000173039 ENSG00000112715 PMC8732357__F2 DDRugging glioblastoma: understanding and targeting the DNA damage response to improve future therapies ENSG00000143799 ENSG00000149311 ENSG00000175054 ENSG00000170430 ENSG00000112039 ENSG00000078098 ENSG00000138385 PMC11566155__F7 Axon guidance pathway analysis ENSG00000107562 ENSG00000145147 ENSG00000070831 ENSG00000173156 ENSG00000288455 ENSG00000121966 ENSG00000113456 ENSG00000182511 ENSG00000172602 ENSG00000010810 ENSG00000071051 ENSG00000164690 ENSG00000154134 ENSG00000128602 ENSG00000185008 ENSG00000075213 PMC3245021__F3 Reformatted modeling of the BioCarta ‘apoptotic signaling in response to DNA damage’ pathway ENSG00000149311 ENSG00000002330 ENSG00000120868 ENSG00000171791 PMC5573916__F3 Simplified mTOR signaling network with interactions inferred from modeling approaches ENSG00000138798 ENSG00000169047 ENSG00000146648 PMC2919228__F6 Systematic Analysis of Essential Genes Reveals New Regulators of G protein Signaling ENSG00000070831 ENSG00000163914 ENSG00000197601 PMC5531453__F5 A, Multifactorial etiology of adhesion formation ENSG00000122194 PMC2981460__F1 TGFB canonical signal transduction pathway and transcriptional responses mediating TGFB growth inhibitory effects PMC7882924__F9 Graphical illustration of the function and mechanism of miR‐144‐3p in combination with hBMSCs ENSG00000135446 PMC11504891__F2 CSF-1R axis mediates the crosstalk between tumor microenvironment cells ENSG00000157368 ENSG00000118520 ENSG00000078098 PMC9512540__F3 Identification of Key Genes and FUNCTIONAL Pathway in Radioresistance of Non-Small Cell Lung Cancer ENSG00000291920 ENSG00000281230 ENSG00000205413 ENSG00000121005 ENSG00000169509 ENSG00000177494 ENSG00000198535 ENSG00000184378 ENSG00000164743 ENSG00000134321 ENSG00000168427 ENSG00000116785 ENSG00000157150 ENSG00000185924 ENSG00000137090 ENSG00000204572 ENSG00000132554 ENSG00000189252 ENSG00000164938 ENSG00000186462 ENSG00000196734 ENSG00000178172 ENSG00000138271 ENSG00000116793 ENSG00000139278 ENSG00000198478 ENSG00000169851 ENSG00000085117 ENSG00000106302 ENSG00000163736 ENSG00000132357 ENSG00000166670 ENSG00000081051 ENSG00000162654 ENSG00000120937 ENSG00000169245 ENSG00000117226 ENSG00000134827 ENSG00000001561 ENSG00000134365 ENSG00000158887 ENSG00000026751 ENSG00000178199 ENSG00000119125 ENSG00000100234 ENSG00000179674 ENSG00000134339 ENSG00000169248 ENSG00000284881 ENSG00000149212 ENSG00000106025 ENSG00000164488 ENSG00000160588 ENSG00000173930 ENSG00000171560 ENSG00000115419 ENSG00000026103 ENSG00000198774 ENSG00000161544 ENSG00000115008 ENSG00000263639 ENSG00000169439 ENSG00000151655 ENSG00000115267 ENSG00000147100 ENSG00000187134 ENSG00000291998 ENSG00000114268 ENSG00000198734 ENSG00000204363 ENSG00000169067 PMC4930117__F1 DNA end resection dictates the pathway choice for both DNA repair and checkpoint response DSBs can be repaired by NHEJ or by HR that requires 3′ ssDNA generated by end resection ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000051180 PMC6413682__F8 Negative regulation between FoxO3a and EPS8 in EGF/PI3K/Akt pathway ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC5573916__F1 Major mTOR signaling network ENSG00000138798 ENSG00000169047 ENSG00000146648 PMC9512540__F6 Identification of Key Genes and FUNCTIONAL Pathway in Radioresistance of Non-Small Cell Lung Cancer ENSG00000169248 ENSG00000169245 ENSG00000134321 ENSG00000115415 ENSG00000115267 PMC4487197__F2 Ephrin receptor signaling pathway (genes hypomethylated in the schizophrenia patient of Twin Pair 1) ENSG00000142192 ENSG00000160145 ENSG00000070831 ENSG00000291971 ENSG00000169439 ENSG00000138798 ENSG00000154188 ENSG00000168610 ENSG00000089159 PMC9590378__F1 Multifunctional role of natural products for the treatment of Parkinson’s disease: At a glance ENSG00000158828 PMC8463184__F3 Idebenone-Activating Autophagic Degradation of Alpha-Synuclein via Inhibition of AKT-mTOR Pathway in a SH-SY5Y-A53T Model of Parkinson's Disease: A Network Pharmacological Approach ENSG00000162889 ENSG00000140992 ENSG00000164129 ENSG00000104365 ENSG00000142192 ENSG00000188822 ENSG00000050748 ENSG00000198793 ENSG00000169710 ENSG00000145386 ENSG00000121879 ENSG00000149295 ENSG00000180210 ENSG00000143801 ENSG00000185386 ENSG00000069482 ENSG00000205155 ENSG00000123374 ENSG00000126895 ENSG00000171608 ENSG00000128602 ENSG00000146648 ENSG00000253729 PMC4613549__F1 Proposed mechanisms of evodiamine signaling in white adipocytes ENSG00000169047 ENSG00000198793 ENSG00000146648 PMC2824633__F4 Cyclin D3-specific deregulated genes and their functional networks ENSG00000112576 ENSG00000003436 ENSG00000141424 ENSG00000114098 ENSG00000060982 ENSG00000124762 ENSG00000145391 ENSG00000116001 ENSG00000145604 ENSG00000118495 ENSG00000100106 ENSG00000196218 ENSG00000176390 ENSG00000120688 ENSG00000105810 ENSG00000133134 ENSG00000167232 ENSG00000144746 ENSG00000089597 PMC8328776__F3 High mobility group box 1 mediates inflammatory response of astrocytes via cyclooxygenase 2/prostaglandin E2 signaling following spinal cord injury ENSG00000069482 ENSG00000149968 ENSG00000163739 ENSG00000108688 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000148344 ENSG00000175505 ENSG00000136630 ENSG00000160691 PMC5715373__F1 Strategies to generate tolDCs for clinical therapeutics ENSG00000026103 PMC7299681__F7 Proposed model of WDR41‐mediated cellular processes in TNBC cells ENSG00000168036 ENSG00000105723 PMC275444__F7 Beta-casein-derived peptides, produced by bacteria, stimulate cancer cell invasion and motility ENSG00000070831 ENSG00000149269 PMC12106489__F7 Wnt7b promoting renal fibrosis in AAN ENSG00000134982 ENSG00000188064 ENSG00000102312 ENSG00000168036 PMC5488057__F1 Conceptual model of general health factors, salient CHD pathogenetic pathways and CHD hallmarks ENSG00000162692 ENSG00000005381 PMC6781771__F5 AKR1C1-3 are involved in a pathway with 44 unique interactors ENSG00000151012 ENSG00000151632 ENSG00000072274 ENSG00000103222 ENSG00000008394 ENSG00000115657 ENSG00000140961 ENSG00000176153 ENSG00000023909 ENSG00000187134 ENSG00000109814 ENSG00000114770 ENSG00000065833 ENSG00000196344 ENSG00000167941 ENSG00000143162 ENSG00000198074 ENSG00000271303 ENSG00000106853 ENSG00000023839 ENSG00000262243 PMC7937672__F1 Cutting the molecular brakes to achieve cardiac regeneration ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000167074 ENSG00000136237 PMC9633658__F1 Muscle-specific MicroRNAs in patients with chronic obstructive pulmonary disease and skeletal muscle dysfunction ENSG00000198793 PMC3480380__F8 Regulation of Epidermal Growth Factor Receptor Signaling and Erlotinib Sensitivity in Head and Neck Cancer Cells by miR-7 ENSG00000002330 ENSG00000163235 ENSG00000105401 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC3932922__F1 Cartoon presentation of LRRK2 showing multidomain structure PMC5115958__F2 Non-invasive metabolic imaging of brain tumors in the era of precision medicine ENSG00000213658 ENSG00000136997 PMC5115958__F1 Non-invasive metabolic imaging of brain tumors in the era of precision medicine ENSG00000136997 ENSG00000078237 PMC4741450__F9 Arenobufagin intercalates with DNA leading to G2 cell cycle arrest via ATM/ATR pathway ENSG00000149311 ENSG00000175054 ENSG00000134057 PMC6004600__F2 Innate immune receptors drive dengue virus immune activation and disease ENSG00000183735 ENSG00000108691 ENSG00000088888 ENSG00000125538 ENSG00000172936 ENSG00000277943 PMC164216__F5 TLR signaling pathways ENSG00000226275 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC8011326__F3 Shh pathway regulated by MID1 ENSG00000101871 ENSG00000164690 PMC8166678__F7 “Metalloestrogenic” effects of cadmium downstream of G protein-coupled estrogen receptor and mitogen-activated protein kinase pathways in human uterine fibroid cells ENSG00000113070 ENSG00000135446 ENSG00000105810 ENSG00000146648 PMC4281293__F2 To reveal potential pathways involved in pancreatic cancer survival, the Ingenuity Pathway Analysis (IPA) was used for upstream regulator analysis ENSG00000197956 ENSG00000166482 ENSG00000112715 ENSG00000067955 ENSG00000146701 ENSG00000013583 PMC9178660__F2 Advances in Immunosuppressive Agents Based on Signal Pathway ENSG00000104856 ENSG00000102871 ENSG00000082512 ENSG00000172936 ENSG00000111321 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC9178660__F4 Advances in Immunosuppressive Agents Based on Signal Pathway ENSG00000133937 ENSG00000118898 ENSG00000079999 PMC11461658__F3 Tryptophan-kynurenine metabolic pathway ENSG00000162882 PMC9178660__F3 Advances in Immunosuppressive Agents Based on Signal Pathway ENSG00000109452 ENSG00000005882 ENSG00000138798 ENSG00000169047 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC8607389__F5 G-protein coupled receptor, PI3K and Rho signaling pathways regulate the cascades of Tau and amyloidB in Alzheimer’s disease ENSG00000163914 ENSG00000173599 ENSG00000198670 PMC8607389__F2 G-protein coupled receptor, PI3K and Rho signaling pathways regulate the cascades of Tau and amyloidB in Alzheimer’s disease ENSG00000213658 ENSG00000070831 ENSG00000146094 ENSG00000134215 ENSG00000198793 ENSG00000115904 ENSG00000160293 PMC4931191__F2 Relationships between longevity genes affected by the diabetic milieu ENSG00000198793 ENSG00000096717 PMC8607389__F1 G-protein coupled receptor, PI3K and Rho signaling pathways regulate the cascades of Tau and amyloidB in Alzheimer’s disease ENSG00000132906 ENSG00000002330 ENSG00000198793 ENSG00000171791 PMC6712508__F6 The proposed mechanism of TN-C release following RV infection of bronchial epithelial cells ENSG00000130164 ENSG00000164342 PMC8289367__F3 Emerging Clinical Application of m6A RNA Modification in Inflammatory Bowel Disease and Its Associated Colorectal Cancer ENSG00000205221 ENSG00000149658 PMC8616136__F1 Perspectives on miRNAs Targeting DKK1 for Developing Hair Regeneration Therapy ENSG00000154342 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000169884 ENSG00000168036 PMC2860348__F1 p38 MAPK mediates the transcriptional response to stress ENSG00000185022 ENSG00000089116 ENSG00000141448 ENSG00000122877 ENSG00000162772 ENSG00000125347 ENSG00000125813 ENSG00000177426 ENSG00000144802 ENSG00000125398 ENSG00000177606 ENSG00000136997 ENSG00000123407 ENSG00000176165 ENSG00000131196 ENSG00000251493 ENSG00000125968 ENSG00000172201 PMC8616136__F3 Perspectives on miRNAs Targeting DKK1 for Developing Hair Regeneration Therapy ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8616136__F6 Perspectives on miRNAs Targeting DKK1 for Developing Hair Regeneration Therapy ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5291375__F7 Deep-proteome mapping of WM-266-4 human metastatic melanoma cells: From oncogenic addiction to druggable targets ENSG00000177455 ENSG00000124102 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000183979 ENSG00000198793 ENSG00000131095 PMC8049318__F1 MiRNAs and coding genes involved in the milk fat synthesis pathway ENSG00000151726 ENSG00000135218 ENSG00000134324 ENSG00000169710 ENSG00000285482 ENSG00000099194 ENSG00000083720 ENSG00000275544 PMC4915567__F1 Melatonin pathway and melatonin candidate genes ENSG00000134640 ENSG00000168412 ENSG00000043591 PMC6437685__F2 HEV infection leads to the expression of IFN and other proinflammatory cytokines through activation of interferon regulatory factor 3 (IRF3) and nuclear factor kB (NFkB) pathways ENSG00000183735 ENSG00000213928 ENSG00000115415 PMC5291375__F3 Deep-proteome mapping of WM-266-4 human metastatic melanoma cells: From oncogenic addiction to druggable targets ENSG00000189283 ENSG00000002330 ENSG00000172005 PMC8482137__F5A Differential Expression of Non-Coding RNA Signatures in Thyroid Cancer between Two Ethnic Groups ENSG00000162676 ENSG00000105329 ENSG00000183625 ENSG00000177606 ENSG00000233816 ENSG00000168610 ENSG00000073861 ENSG00000142166 PMC12163381__F4 ILs with dual functions ENSG00000137033 ENSG00000115415 ENSG00000105639 ENSG00000168610 PMC10937442__F8 Off-label use of Baricitinib improves moderate and severe atopic dermatitis in China through inhibiting MAPK and PI3K/Akt/mTOR pathway via targeting JAK-STAT signaling of CD4+ cells ENSG00000113520 ENSG00000113525 PMC12163381__F3 ILs mitigating AKI progression ENSG00000100385 ENSG00000138378 ENSG00000123496 ENSG00000105397 ENSG00000115415 ENSG00000056736 ENSG00000105639 ENSG00000168610 PMC12163381__F2 ILs exacerbating AKI progression ENSG00000138378 ENSG00000105397 ENSG00000115415 ENSG00000168610 PMC3826519__F7 Deregulated genes upon miR-196a overexpression in keratinocytes ENSG00000142192 ENSG00000078399 ENSG00000149294 ENSG00000205250 ENSG00000135587 ENSG00000103479 ENSG00000108691 ENSG00000112242 ENSG00000078900 ENSG00000102245 ENSG00000123374 ENSG00000285485 ENSG00000139687 ENSG00000026103 ENSG00000182253 PMC2737093__F6 Schematic view of PPARG activation in VSMCs PMC10571713__F1 Lipid sources include the de novo fatty acid synthesis pathway and exogenous lipid uptake ENSG00000131473 ENSG00000169710 ENSG00000026103 PMC7508399__F5 Early immune suppression leads to uncontrolled mite proliferation and potent host inflammatory responses in a porcine model of crusted versus ordinary scabies ENSG00000291761 ENSG00000062485 PMC8316833__F3 SUMO and SUMOylation Pathway at the Forefront of Host Immune Response ENSG00000115415 ENSG00000140968 ENSG00000137265 ENSG00000132256 ENSG00000168310 ENSG00000125347 ENSG00000168610 ENSG00000276561 ENSG00000136826 PMC3154612__F1 Simplified diagram illustrating the mTOR signaling pathway ENSG00000198793 PMC6660835__F1 Endogenous Nucleic Acid Recognition by RIG-I-Like Receptors and cGAS ENSG00000183735 ENSG00000088888 ENSG00000112110 PMC10382489__F3 PTMs involve some mechanisms in CVDs ENSG00000116688 ENSG00000265972 ENSG00000159335 ENSG00000171109 PMC8289367__F2 Emerging Clinical Application of m6A RNA Modification in Inflammatory Bowel Disease and Its Associated Colorectal Cancer ENSG00000149658 ENSG00000126353 ENSG00000150455 ENSG00000165819 PMC2950652__F2 Pioneer Round of Translation: Features and Functions ENSG00000162385 ENSG00000070756 ENSG00000163435 ENSG00000282825 PMC4657151__F1 Skeletal muscle as an endocrine organ: PGC-1A, myokines and exercise ENSG00000198793 ENSG00000096717 ENSG00000142082 PMC6961892__F7 Liganded T3 receptor B2 inhibits the positive feedback autoregulation of the gene for GATA2, a transcription factor critical for thyrotropin production ENSG00000168066 ENSG00000170893 ENSG00000163132 ENSG00000179348 ENSG00000134200 PMC3429058__F1 HDL promotes regression ENSG00000135218 ENSG00000126353 PMC11411607__F3 Canonical and non-canonical NFKB signaling pathways by andrographolide ENSG00000104856 ENSG00000186716 ENSG00000173039 PMC4299486__F2 Endocrine system development and function ENSG00000169594 ENSG00000169618 ENSG00000170011 ENSG00000167772 ENSG00000111729 ENSG00000116194 ENSG00000186847 ENSG00000198829 ENSG00000072315 ENSG00000291917 ENSG00000100739 ENSG00000147262 PMC4299486__F1 Cell signaling ENSG00000090061 ENSG00000185515 ENSG00000142192 ENSG00000105329 ENSG00000155827 ENSG00000147138 ENSG00000175093 ENSG00000172057 ENSG00000174946 ENSG00000180758 ENSG00000157005 PMC7918665__F2 Major groups of micro RNAs (miRNAs) and their related pathways by which they act on endothelial cells ENSG00000198793 ENSG00000163631 PMC9178660__F6 Advances in Immunosuppressive Agents Based on Signal Pathway ENSG00000070831 ENSG00000102871 ENSG00000130522 ENSG00000149269 ENSG00000127191 ENSG00000026103 PMC9178660__F5 Advances in Immunosuppressive Agents Based on Signal Pathway ENSG00000138798 PMC2820658__F1 Induction of IFNs after virus infection in IFNB pretreated human DCs ENSG00000105397 ENSG00000276561 PMC7850581__F1 Interferon-stimulated GTPases in autoimmune and inflammatory diseases: promising role for the guanylate-binding protein (GBP) family ENSG00000154451 ENSG00000213928 ENSG00000281324 ENSG00000117228 ENSG00000162337 ENSG00000105397 ENSG00000115415 ENSG00000134982 ENSG00000173039 ENSG00000168036 PMC6321285__F1 HGF/c-MET signaling ENSG00000019991 ENSG00000291971 ENSG00000149269 ENSG00000198793 ENSG00000168610 PMC7980187__F9 Possible signaling pathways utilized by SARS-CoV-2 for cellular hijacking ENSG00000124102 ENSG00000291971 ENSG00000130234 ENSG00000163914 ENSG00000113263 PMC1083688__F2 Curbing the nuclear activities of Beta-catenin ENSG00000087095 ENSG00000101751 PMC8318926__F1 Portal hypertension in cirrhosis: Pathophysiological mechanisms and therapy ENSG00000163739 PMC6349702__F2 Protein-Protein interaction network of the 214 identified proteins: network nodes represent proteins, network edges indicate the strength of data support (STRING v10.5) ENSG00000166794 ENSG00000143549 ENSG00000166974 ENSG00000013016 ENSG00000291971 ENSG00000169756 ENSG00000134308 ENSG00000173083 ENSG00000163736 ENSG00000105402 ENSG00000163737 ENSG00000105205 ENSG00000137801 ENSG00000064666 ENSG00000115956 ENSG00000161634 ENSG00000291814 ENSG00000144118 ENSG00000148175 ENSG00000146701 ENSG00000132341 ENSG00000122678 PMC7198573__F3 Map of the T-cell receptor signalling KEGG pathway for Mus musculus, with the colour of nodes representing the level of individual variability in response to stimulation with anti-CD3 and anti-CD28 antibodies in Microtus agrestis ENSG00000140992 ENSG00000104365 ENSG00000291603 ENSG00000170369 ENSG00000109320 ENSG00000198851 ENSG00000269335 ENSG00000213341 ENSG00000135341 ENSG00000006062 ENSG00000185386 ENSG00000213658 ENSG00000135446 ENSG00000167941 ENSG00000149269 ENSG00000102245 ENSG00000010810 ENSG00000198286 PMC5695813__F5 Mass spectrometry-based quantification of the cellular response to ultraviolet radiation in HeLa cells ENSG00000134899 ENSG00000292191 ENSG00000291803 ENSG00000132383 ENSG00000277273 ENSG00000035928 ENSG00000177084 ENSG00000133119 PMC5457443__F6 Functional analysis of IRF5 pathway ENSG00000077152 ENSG00000182156 ENSG00000198515 ENSG00000086758 ENSG00000169836 ENSG00000059758 ENSG00000183484 ENSG00000178974 ENSG00000152208 ENSG00000184012 ENSG00000169727 ENSG00000080709 ENSG00000165192 ENSG00000182170 ENSG00000173456 ENSG00000152556 PMC8905437__F1 Key Enzymes in Fatty Acid Synthesis Pathway for Bioactive Lipids Biosynthesis ENSG00000138433 PMC9426616__F2 Human immune polymorphisms associated with the risk of cryptococcal disease ENSG00000174123 ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187796 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC3906588__F1 UPR response underling memory consolidation in Alzheimer's disease ENSG00000142192 ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC6879357__F6 Long non-coding RNA TCONS_00000200 as a non-invasive biomarker in patients with intracranial aneurysm ENSG00000149564 ENSG00000169896 ENSG00000081237 ENSG00000196358 ENSG00000134982 ENSG00000197471 ENSG00000179242 ENSG00000170558 ENSG00000173482 ENSG00000091409 ENSG00000007908 ENSG00000150637 ENSG00000110876 ENSG00000292348 ENSG00000181847 ENSG00000188404 ENSG00000160223 ENSG00000158887 ENSG00000165376 ENSG00000154721 ENSG00000174059 ENSG00000115232 ENSG00000139626 PMC4506163__F4 Gene product association networks extracted from the most significant (A) cellular and regulatory process pathways and (B) metabolic pathways involved in arteriotomy-induced carotid stenosis (listed in Table ) ENSG00000074800 ENSG00000129518 PMC7316184__F1 Trimethylamine N-oxide (TMAO) metaorganismal pathway ENSG00000162711 ENSG00000150907 ENSG00000118777 PMC12245910__F2 The TSCC in the mTORC1 signaling pathway ENSG00000198793 ENSG00000145979 ENSG00000155792 ENSG00000167965 PMC3836826__F3 Stress-response pathways are altered in the hippocampus of chronic alcoholics ENSG00000125538 ENSG00000136869 ENSG00000265972 PMC7883599__F4 SIRT1 and SIRT2 in Huntington’s disease ENSG00000096717 ENSG00000283100 PMC9152417__F8 Extracellular Vesicles Carrying miR-887-3p Promote Breast Cancer Cell Drug Resistance by Targeting BTBD7 and Activating the Notch1/Hes1 Signaling Pathway ENSG00000148400 ENSG00000114315 ENSG00000277222 PMC7736111__F2 Molecular and signaling pathway implicated in host cell antiviral response ENSG00000183735 ENSG00000088888 ENSG00000102871 ENSG00000130234 ENSG00000082512 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000121060 ENSG00000276561 PMC10476815__F6 Predicted targets of Ruxian Shuhou prescription in the PI3-Akt signaling pathway ENSG00000177455 ENSG00000132906 ENSG00000103479 ENSG00000002330 ENSG00000069482 ENSG00000186716 ENSG00000198793 ENSG00000136997 ENSG00000104894 PMC4400874__F3 Initiation and perpetuation of NLRP3 inflammasome activation and assembly ENSG00000162711 ENSG00000187688 ENSG00000036828 ENSG00000173612 PMC3285438__F5 Simplified signaling pathway of the effects of resveratrol involved in metabolic control in the skeletal muscle ENSG00000138207 ENSG00000169047 ENSG00000096717 PMC6089393__F9 PM2.5 induced cardiac hypertrophy via CREB/GSK3b/SOS1 pathway and metabolomics alterations ENSG00000175893 ENSG00000122180 ENSG00000285109 ENSG00000172572 ENSG00000127528 ENSG00000112715 ENSG00000081189 ENSG00000157557 ENSG00000136160 ENSG00000185591 ENSG00000168398 ENSG00000142546 ENSG00000179348 ENSG00000136448 ENSG00000152465 PMC10458348__F4 Histone Modification of Colorectal Cancer by Natural Products ENSG00000281324 ENSG00000134982 ENSG00000136997 ENSG00000026508 ENSG00000168036 PMC3269610__F2 BMP signaling and negative regulation in bone formation ENSG00000178860 ENSG00000167941 PMC5743847__F1 Lipoquality control by phospholipase A2 enzymes ENSG00000226275 PMC3309723__F5 Parp1 mediation of Sox2 activity in ESC pluripotency ENSG00000143799 ENSG00000128342 ENSG00000168610 ENSG00000227345 PMC11531143__F4 PIM1-mediated signaling pathways in lung cancer ENSG00000198793 ENSG00000137193 ENSG00000157625 ENSG00000159399 PMC11531143__F3 PIM1 signaling in Hepatocellular carcinoma ENSG00000002330 ENSG00000137193 ENSG00000146648 PMC11531143__F5 PIM1 activates AKT signaling in ovarian cancer ENSG00000002330 ENSG00000138798 ENSG00000198793 ENSG00000137193 ENSG00000105810 ENSG00000146648 PMC9659297__F4 Biological Relevance of Papaverine in Cancer Cells ENSG00000138798 ENSG00000198793 ENSG00000163914 ENSG00000164327 PMC8157467__F7 3-Methyladenine but not antioxidants to overcome BACH2-mediated bortezomib resistance in mantle cell lymphoma ENSG00000112182 ENSG00000156273 PMC6053318__F2 Everolimus and Sirolimus in Transplantation-Related but Different ENSG00000002330 ENSG00000169047 PMC3880796__F2 TRAIL on Trial: Preclinical advances for cancer therapy ENSG00000132906 ENSG00000120868 ENSG00000168040 ENSG00000164305 PMC4576979__F4 Harnessing the apoptotic programs in cancer stem-like cells PMC11531143__F2 PIM1 enhances aggressive oncogenic characteristics in breast cancer through multiple mechanisms ENSG00000165119 ENSG00000002330 ENSG00000148400 ENSG00000074181 ENSG00000137193 ENSG00000020633 ENSG00000116489 ENSG00000131196 ENSG00000124762 ENSG00000130726 PMC4823938__F1 Schematic overview of necroptotic pathway ENSG00000213928 ENSG00000102871 ENSG00000136869 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000125347 ENSG00000168610 ENSG00000276561 ENSG00000164342 PMC11531143__F1 PIM kinase family gene structures ENSG00000120833 ENSG00000078399 ENSG00000137193 ENSG00000198355 ENSG00000292210 PMC9627168__F2 Lactate drives cellular DNA repair capacity: Role of lactate and related short-chain fatty acids in cervical cancer chemoresistance and viral infection ENSG00000166816 PMC3107442__F5 Transcripts (p < 0.05) involved in cell signaling ENSG00000124493 ENSG00000164082 PMC8210623__F4 Analyzing signaling activity and function in hematopoietic cells ENSG00000172936 ENSG00000136869 PMC9283712__F1 TNFA Inhibitors and Other Biologic Agents for the Treatment of Immune Checkpoint Inhibitor-Induced Myocarditis ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC5417301__F11 Model summarizing the regulation of GR by TTC5 ENSG00000152409 PMC7761238__F1 Interaction of interleukin-2 (IL-2) and IL-15 with their receptors and downstream signaling pathways ENSG00000134460 ENSG00000198793 ENSG00000105639 ENSG00000168610 PMC4587761__F3 Network associated with the proteins in ENSG00000003436 ENSG00000170458 ENSG00000178772 ENSG00000244731 ENSG00000157017 ENSG00000038945 ENSG00000122194 ENSG00000112293 ENSG00000236625 ENSG00000123610 PMC7359176__F3 Unphosphorylated glycogen synthase kinase-3B (GSK-3B) and canonical WNT/Beta-catenin signaling in “off” state ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC7359176__F2 Phosphorylated glycogen synthase kinase-3B (pGSK-3B) and canonical WNT/Beta-catenin signaling in “on” state ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6795080__F1 Mevalonate pathway intermediates active in feedback control ENSG00000132196 ENSG00000001630 ENSG00000116133 ENSG00000143815 ENSG00000149809 ENSG00000052802 PMC2773299__F2 Schematic representations of the activated RAS-MAPK, RASSF1A/NORE1A, and Dab2IP/ASK1 pathways, iNOS signalling, and FOXM1-related pathways involved in the dysregulation of cell growth and apoptosis in HCC ENSG00000145604 ENSG00000117650 ENSG00000105401 ENSG00000136848 ENSG00000087586 ENSG00000101224 ENSG00000112715 PMC5010756__F4 Sensing of HMPV by different PRRs and modulation of the IFN response by viral proteins ENSG00000088888 ENSG00000105397 ENSG00000172936 ENSG00000136869 ENSG00000276561 ENSG00000164342 PMC4600616__F1 Sonic Hedgehog in SCLC ENSG00000163914 ENSG00000164690 ENSG00000128602 PMC4904844__F5 Interaction network of 135 SNO-modified proteins identified in WT and AD mouse brain tissues ENSG00000074800 ENSG00000169750 ENSG00000131495 ENSG00000122705 ENSG00000146701 ENSG00000101365 ENSG00000062485 PMC6281417__F7 Human liver stem cell-derived extracellular vesicles enhance cancer stem cell sensitivity to tyrosine kinase inhibitors through Akt/mTOR/PTEN combined modulation ENSG00000198793 PMC8781199__F2 Abnormal mTOR Activity in Pediatric Autoimmune Neuropsychiatric and MIA-Associated Autism Spectrum Disorders ENSG00000115484 ENSG00000070756 ENSG00000170606 ENSG00000120438 ENSG00000146731 ENSG00000135624 PMC9527825__F1 Possible mechanisms for ANGPTL1 attenuating CRC liver metastasis ENSG00000288335 ENSG00000100985 PMC5742686__F3 The NLRP3 inflammasome in ORKD development ENSG00000162711 ENSG00000125538 ENSG00000136869 ENSG00000265972 PMC5535903__F2 Nucleolar response to DNA damage ENSG00000149311 ENSG00000012048 ENSG00000181163 ENSG00000165392 ENSG00000197299 ENSG00000051180 ENSG00000280548 PMC3260814__F1 Personalizing Therapy with Targeted Agents in Non-Small Cell Lung Cancer ENSG00000198793 ENSG00000146648 PMC3915522__F5 Ras oncogenes: split personalities ENSG00000017797 ENSG00000070831 ENSG00000163914 ENSG00000282895 PMC7927090__F2 Summary of key pathways regulated by H2S donors in the treatment of CVDs ENSG00000128272 ENSG00000198793 ENSG00000118515 ENSG00000096717 ENSG00000175104 ENSG00000127191 ENSG00000168610 PMC2840045__F1 Innate immune responses in allotransplantation ENSG00000189403 ENSG00000136869 PMC9557197__F1 Ferroptosis in glioma treatment: Current situation, prospects and drug applications ENSG00000168003 ENSG00000167468 ENSG00000115107 PMC6861914__F7 Apoptosis pathway in LNCaP cells treated with LEP (1 × 10−6 M) ENSG00000292096 ENSG00000065833 ENSG00000002330 ENSG00000138794 ENSG00000291791 ENSG00000168040 ENSG00000127191 ENSG00000135116 ENSG00000084774 PMC6861914__F6 p53 signaling pathway in LNCaP cells treated with LEP (1 × 10−6 M) ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000136997 ENSG00000042286 ENSG00000123374 ENSG00000112378 ENSG00000196470 ENSG00000120868 ENSG00000164305 PMC11278074__F1 Therapeutic approaches to vascular Ehlers–Danlos syndrome ENSG00000175054 ENSG00000291971 ENSG00000100985 PMC4502774__F1 Schematic stages of the autophagic pathway ENSG00000124102 ENSG00000177169 ENSG00000110497 ENSG00000152348 ENSG00000097033 ENSG00000123395 ENSG00000198382 ENSG00000083290 ENSG00000126775 ENSG00000198793 ENSG00000171791 ENSG00000136874 ENSG00000057663 ENSG00000144848 ENSG00000145782 PMC3480285__F5 A Systems Biology View of Responses to Lignin Biosynthesis Perturbations in Arabidopsis ENSG00000213658 ENSG00000183625 ENSG00000102977 ENSG00000062485 PMC3480285__F1 Metabolic Map of Phenolic Metabolism in the Inflorescence Stem of Arabidopsis.The main pathways involved in lignin biosynthesis are framed with a bold black border ENSG00000157005 ENSG00000062485 PMC4590996__F2 Biomarkers of primary open-angle glaucoma ENSG00000183735 ENSG00000170458 ENSG00000026508 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC8662602__F1 Evolutionary Profile for (Host and Viral) MLKL Indicates Its Activities as a Battlefront for Extensive Counteradaptation ENSG00000124256 ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC4254928__F3 Insights into Molecular Features of Venerupis decussata Oocytes: A Microarray-Based Study ENSG00000162552 ENSG00000281324 ENSG00000134982 ENSG00000168036 ENSG00000161202 ENSG00000177283 PMC7367617__F3 KEGG enrichment of 249 DEGs identified between chemotherapy sensitive and insensitive OC ENSG00000081041 ENSG00000226275 ENSG00000113070 ENSG00000177606 ENSG00000163734 ENSG00000130222 PMC8509036__F1 B Cell Lymphoma 2: A Potential Therapeutic Target for Cancer Therapy ENSG00000002330 ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC4202122__F2 Altered Mucins (MUC) Trafficking in Benign and Malignant Conditions ENSG00000168461 ENSG00000168036 ENSG00000146648 ENSG00000213024 PMC7106881__F9 Hypothetical action mechanism of aspirin on nonalcoholic fatty liver and atherosclerosis ENSG00000113161 ENSG00000121807 ENSG00000026103 PMC4586018__F6 Reversal of diet-induced obesity and insulin resistance by inducible genetic ablation of GRK2 ENSG00000042832 PMC6520588__F3 Schematic drawing showing proposed mechanisms of action of Curcuma longa (curcumin) ENSG00000142192 ENSG00000154016 PMC6805653__F10 Molecular mechanism of miR-129-5p regulation of ZIC2 expression and the Wnt/Beta-catenin signaling pathway in PCa ENSG00000043355 ENSG00000170558 ENSG00000168036 PMC3760627__F2 Diving adaptations in the Chinese alligator genome ENSG00000154269 ENSG00000136521 ENSG00000152904 ENSG00000174915 ENSG00000170266 ENSG00000197142 ENSG00000047230 ENSG00000166278 ENSG00000122971 ENSG00000116649 ENSG00000102172 ENSG00000156471 PMC4248697__F2 Synthesis of isoprenoid products in P ENSG00000197429 PMC7559774__F3 tRF-Leu-CAG, ts-101, ts-46, and ts-47 are involved in drug resistance of lung cancer cells ENSG00000291971 ENSG00000144118 ENSG00000198793 ENSG00000087586 PMC3092098__F1 The genes and pathways associated with Crohn's disease pathogenesis ENSG00000134460 ENSG00000187796 ENSG00000164691 ENSG00000163235 ENSG00000160223 ENSG00000162924 ENSG00000237693 ENSG00000076662 ENSG00000115009 PMC8980325__F1 Lipid Metabolism Regulation Based on Nanotechnology for Enhancement of Tumor Immunity ENSG00000131473 ENSG00000113161 ENSG00000099194 ENSG00000026103 PMC7395594__F6 Nrf2/Wnt/immune crosstalk in oxidative stress and inflammation in PD ENSG00000134982 ENSG00000079999 PMC9688663__F1 Advances in Understanding of Metabolism of B-Cell Lymphoma: Implications for Therapy ENSG00000284320 ENSG00000228716 ENSG00000092621 ENSG00000291971 ENSG00000136997 ENSG00000105953 ENSG00000010671 PMC6261607__F8 Novel high–throughput myofibroblast assays identify agonists with therapeutic potential in pulmonary fibrosis that act via EP2 and EP4 receptors PMC6250427__F4 Mitogen activated protein kinase (MAPK) signaling pathway ENSG00000136997 PMC5109738__F5 Proposed novel caspase-1 working models ENSG00000099330 ENSG00000162711 PMC7335630__F2 Immunological response of SARS-CoV-2 ENSG00000130234 ENSG00000184012 PMC4716095__F1 mTOR signaling ENSG00000118515 PMC6529242__F5 Mechanisms induced by MC-GAG on osteoprogenitors and osteoclast progenitors ENSG00000170365 PMC8841737__F2 Noncoding RNAs in Drug Resistance of Gastrointestinal Stromal Tumor ENSG00000157404 ENSG00000198793 ENSG00000066739 ENSG00000072135 ENSG00000150457 ENSG00000168610 ENSG00000131023 ENSG00000140443 PMC7856198__F5 Gene identification and pathway Network Analyses of the IL-4R responsive transcripts in the metabolic MMC9 cluster ENSG00000124422 ENSG00000065911 ENSG00000130826 ENSG00000278461 ENSG00000107890 ENSG00000167552 ENSG00000076003 ENSG00000103490 ENSG00000283018 ENSG00000156958 ENSG00000158825 ENSG00000204520 ENSG00000144029 PMC4403665__F1 Chemotherapeutic Targeting of the Transforming Growth FactorB Pathway in Breast Cancers ENSG00000291971 ENSG00000198793 PMC2242712__F1 Phenolic lipid synthesis in A ENSG00000166278 PMC8165235__F1 Perspective: Humanized Pig Models of Bladder Cancer ENSG00000121879 PMC3269833__F6 Potential regulatory mechanism of the identified gene switches for breast cancer ENSG00000108551 ENSG00000184292 ENSG00000133134 PMC7501082__F2 Involvement of host and viral proteases in SARS-CoV-2 life cycle ENSG00000140564 ENSG00000130234 ENSG00000184012 PMC8493693__F4 Identification of disease- and headache-specific mediators and pathways in migraine using blood transcriptomic and metabolomic analysis ENSG00000241468 ENSG00000167283 ENSG00000169021 ENSG00000073578 ENSG00000179091 ENSG00000117118 ENSG00000138495 ENSG00000178741 ENSG00000166260 ENSG00000156467 ENSG00000006695 ENSG00000143252 ENSG00000241837 ENSG00000127184 ENSG00000131174 ENSG00000116459 PMC8913874__F5 How water‐soluble saccharides drive the metabolism of lactic acid bacteria during fermentation of brewers' spent grain PMC10311176__F3 Transcriptome analysis of CD4+ T cells from HIV-infected individuals receiving ART with LLV revealed novel transcription factors regulating HIV-1 promoter activity ENSG00000125740 ENSG00000105967 ENSG00000119508 ENSG00000165030 ENSG00000122877 ENSG00000162772 ENSG00000136826 ENSG00000196628 ENSG00000245848 ENSG00000157227 ENSG00000125538 ENSG00000137265 ENSG00000152217 ENSG00000073792 ENSG00000169429 ENSG00000197943 ENSG00000136869 ENSG00000179094 ENSG00000128342 ENSG00000144655 ENSG00000095794 ENSG00000155090 ENSG00000178860 ENSG00000111249 ENSG00000081041 ENSG00000169554 ENSG00000100906 ENSG00000204103 ENSG00000078399 ENSG00000140968 ENSG00000101057 ENSG00000124766 ENSG00000221869 ENSG00000175029 ENSG00000073756 ENSG00000277943 ENSG00000118503 ENSG00000146592 ENSG00000177606 ENSG00000135114 ENSG00000151650 ENSG00000196092 ENSG00000152804 ENSG00000100985 ENSG00000073861 ENSG00000173334 PMC10911341__F9 Potential mechanisms of inhibiting Perk-ATF4-P21 pathway to enhance the efficacy of MPPAlpha-PDT ENSG00000128272 ENSG00000144895 ENSG00000057663 PMC11589783__F5 KEGG graphical of MAPK signaling pathway32 ENSG00000151657 ENSG00000170458 ENSG00000102871 ENSG00000130522 ENSG00000138798 ENSG00000162924 ENSG00000101224 ENSG00000175104 ENSG00000026103 PMC3296202__F1 Pathways involved in diabetes-induced EPCs toxicity and possible strategies to reverse EPCs damage during bone marrow mobilization ENSG00000100985 ENSG00000047936 ENSG00000121966 PMC11589783__F6 KEGG graphical of FoxO signaling pathway32 ENSG00000145604 ENSG00000087095 ENSG00000171105 ENSG00000213658 ENSG00000005882 ENSG00000138798 ENSG00000123374 ENSG00000176165 ENSG00000168610 ENSG00000146648 PMC9502082__F1 RIOK3 and Its Alternatively Spliced Isoform Have Disparate Roles in the Innate Immune Response to Rift Valley Fever Virus (MP12) Infection ENSG00000183735 ENSG00000088888 PMC2923990__F7 Model for C ENSG00000187796 ENSG00000172936 ENSG00000136869 PMC2889938__F2 Target gene regulatory network, NFKB/RelA:P50 ENSG00000110944 ENSG00000104856 ENSG00000134460 ENSG00000105329 ENSG00000163629 ENSG00000163739 ENSG00000171791 ENSG00000117525 ENSG00000138755 ENSG00000136997 ENSG00000125538 ENSG00000164400 ENSG00000026103 ENSG00000023445 ENSG00000100811 ENSG00000081041 ENSG00000117228 ENSG00000100906 ENSG00000109320 ENSG00000173039 ENSG00000125347 ENSG00000276561 ENSG00000138378 ENSG00000164136 ENSG00000100985 ENSG00000162692 ENSG00000110911 PMC5645611__F1 One marker is not enough for designate one cell as cancer stem cell ENSG00000119888 ENSG00000272398 ENSG00000026508 ENSG00000168036 PMC11637887__F3 Comparison of changes in the eye among normal, non-proliferative diabetic retinopathy (NPDR), and proliferative diabetic retinopathy (PDR), and the signaling pathways of DNA methylation alterations associated with DR development PMC11637887__F6 Impact of DNA Methylation on Schizophrenia PMC4102070__F4 Points of inhibition for ibrutinib, idelalisib, fostamatinib, and Lck-i in the BCR signaling pathway ENSG00000095585 ENSG00000197943 ENSG00000010671 PMC11637887__F7 DNA methylation changes in the pathogenesis of HD and the cellular impact of toxic huntingtin protein variants ENSG00000012048 ENSG00000132383 PMC6351542__F5 S-nitrosylation of E3 ubiquitin-protein ligase RNF213 alters non-canonical Wnt/Ca+2 signaling in the P301S mouse model of tauopathy ENSG00000198838 ENSG00000196218 ENSG00000123104 ENSG00000086544 PMC4102070__F2 Signal integration following BCR engagement ENSG00000095585 ENSG00000197943 ENSG00000152689 ENSG00000010671 PMC9509681__F7 Relevance of Host Gut Microbiome Signature Alterations on de novo Fatty Acids Synthesis in Patients with Multi-Drug Resistant Tuberculosis ENSG00000131473 ENSG00000026103 PMC8964949__F6 Metalloprotease-Disintegrin ADAM8 Alters the Tumor Suppressor miR-181a-5p Expression Profile in Glioblastoma Thereby Contributing to Its Aggressiveness ENSG00000118785 ENSG00000138798 ENSG00000100985 ENSG00000168610 PMC8774282__F2 Breakthrough Brought about by Targeting KRASG12C: Nonconformity Is Punished ENSG00000198793 ENSG00000171540 PMC3610285__F2 Melanogenesis ENSG00000166501 ENSG00000168036 ENSG00000136160 ENSG00000080166 ENSG00000107165 PMC2696814__F1 Autophagy in the Pathogenesis of Disease ENSG00000152348 ENSG00000110497 ENSG00000198382 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC6485060__F2 CircRNA regulates cell proliferation ENSG00000112242 ENSG00000110395 ENSG00000078747 ENSG00000134982 ENSG00000168036 ENSG00000123374 ENSG00000105810 ENSG00000146648 ENSG00000140443 PMC4104550__F1 ALK signaling pathway with its cross-talk with other pathways involved in the resistance to ALK-inhibitors ENSG00000002330 ENSG00000198793 ENSG00000105639 PMC11549395__F5 Regulatory network of the 32 DEMs and the 66 DEM-regulated DEGs was drawn by Cytoscape 3 ENSG00000105697 ENSG00000174804 ENSG00000087586 ENSG00000135476 ENSG00000277641 ENSG00000117399 ENSG00000093009 ENSG00000137812 ENSG00000128710 ENSG00000063660 ENSG00000122691 ENSG00000112742 ENSG00000071539 PMC4092085__F2 Na+, K+-ATPase-mediated signal transduction ENSG00000146648 PMC5406167__F6 Mobile-phone radiation-induced perturbation of gene-expression profiling, redox equilibrium and sporadic-apoptosis control in the ovary of Drosophila melanogaster ENSG00000109118 ENSG00000124217 ENSG00000151835 ENSG00000100325 ENSG00000168701 ENSG00000102974 PMC3808235__F1 Pathway-guided treatment in prostate cancer ENSG00000198793 ENSG00000087586 PMC8596126__F8 M6A Readers YTHDF1 and YTHDF2 Synergistically Control Cerebellar Parallel Fiber Growth by Regulating Local Translation of the Key Wnt5a Signaling Components in Axons ENSG00000149658 ENSG00000198492 ENSG00000104290 PMC9124571__F2 Immune cells in cardiac repair and regeneration ENSG00000150782 ENSG00000153208 ENSG00000108691 ENSG00000108688 ENSG00000113520 ENSG00000121807 ENSG00000112115 PMC3188704__F1 Regulation of cell migration by signaling endosomes ENSG00000070831 ENSG00000156299 ENSG00000291971 ENSG00000163914 ENSG00000165527 ENSG00000146648 PMC7986631__F1 Cannabinoid biosynthesis including polyketide and isoprenoid precursor pathways ENSG00000184357 ENSG00000197429 PMC2762604__F11 Proteomic and Phospho-Proteomic Profile of Human Platelets in Basal, Resting State: Insights into Integrin Signaling ENSG00000140992 ENSG00000169814 ENSG00000291971 PMC5713906__F1 Hh signaling and how pathogens may modify pathway activity ENSG00000291363 ENSG00000176692 ENSG00000167779 ENSG00000125538 ENSG00000136997 ENSG00000288335 ENSG00000184916 ENSG00000128602 PMC4095756__F2A GRK2 – A Link Between Myocardial Contractile Function and Cardiac Metabolism ENSG00000169047 ENSG00000198793 PMC3324133__F1 Insulin receptor (INSR) belongs to a family of receptor tyrosine kinases that includes the receptor for insulin-like growth factor 1 (IGF-1R) ENSG00000171105 ENSG00000002330 ENSG00000198793 ENSG00000110931 ENSG00000168610 PMC3390632__F1 Overexpression of the Coq8 Kinase in Saccharomyces cerevisiae coq Null Mutants Allows for Accumulation of Diagnostic Intermediates of the Coenzyme Q6 Biosynthetic Pathway ENSG00000136152 ENSG00000110871 ENSG00000164597 ENSG00000173085 PMC7369945__F1 Androgen “backdoor” steroidogenesis pathway ENSG00000203859 PMC5209581__F5 Phosphatidylinositol 3-kinase (PI3K) pathway: Activation of class IA/B PI3Ks occurs through the stimulation of receptor tyrosine kinases, which is induced by insulin and the concomitant assembly of receptor–PI3K complexes ENSG00000002330 ENSG00000150907 ENSG00000198793 PMC5960455__F1 Role of WNT/beta-catenin signaling in gliomas ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000168610 PMC7488916__F6 Working model for amplified cross-talk between CXCR4 and EGFR to promote gastric cancer metastasis ENSG00000107562 ENSG00000138798 ENSG00000146648 ENSG00000121966 PMC5124975__F3 Galectin-3 and IL-33/ST2 axis interaction in diet-induced steatohepatitis ENSG00000137033 PMC8835853__F1 Cortical Dysplasia and the mTOR Pathway: How the Study of Human Brain Tissue Has Led to Insights into Epileptogenesis ENSG00000100150 ENSG00000114388 ENSG00000145979 ENSG00000167965 PMC2664745__F1 Molecular and cellular biology of enhanced cognition ENSG00000117245 PMC5700087__F8 The proposed mechanism of BBB disruption in CNS TB ENSG00000164690 ENSG00000128602 PMC8156218__F1 Pentraxin 3: a powerful orchestrator in urinary tract infection ENSG00000172936 ENSG00000136869 ENSG00000163661 PMC6726833__F7 Functional roles of SALL4 in cervical cancer cells ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000101115 ENSG00000168036 PMC12000890__F1 Traditional Chinese medicine compounds modulate signaling pathways to improve cardiac-related pathology ENSG00000136869 PMC3356080__F4 Factors and molecular mechanisms that influence ecdysone synthesis and the timing of critical weight attainment PMC12000890__F3 Traditional Chinese medicine compounds modulate signaling pathways to improve cardiac-related pathology ENSG00000162711 ENSG00000172936 ENSG00000175104 PMC12000890__F2 Traditional Chinese medicine compounds modulate signaling pathways to improve cardiac-related pathology ENSG00000177169 ENSG00000139687 PMC10379125__F5 Transcriptome-Wide Identification and Response Pattern Analysis of the Salix integra NAC Transcription Factor in Response to Pb Stress ENSG00000015285 ENSG00000111962 PMC12000890__F4 Traditional Chinese medicine compounds modulate signaling pathways to improve cardiac-related pathology ENSG00000142082 ENSG00000079999 PMC4401249__F5 DIANA miRPath analysis of target genes for miRNAs downregulated in AD blood ENSG00000177455 ENSG00000124102 ENSG00000103479 ENSG00000142192 ENSG00000033327 ENSG00000002330 ENSG00000067606 ENSG00000186716 ENSG00000198793 ENSG00000120885 ENSG00000105810 ENSG00000197461 PMC12024652__F1 Signaling pathway of necroptosis and its PTMs ENSG00000079387 ENSG00000186660 ENSG00000102871 ENSG00000291971 ENSG00000105401 ENSG00000166851 ENSG00000292096 ENSG00000183735 ENSG00000078747 ENSG00000138032 ENSG00000157625 ENSG00000168404 ENSG00000159335 ENSG00000143499 ENSG00000143258 ENSG00000219607 ENSG00000177169 ENSG00000124422 ENSG00000118518 ENSG00000142192 ENSG00000137275 ENSG00000126457 ENSG00000168040 ENSG00000154124 ENSG00000127191 ENSG00000283100 ENSG00000145604 ENSG00000197530 ENSG00000083799 ENSG00000096717 ENSG00000121060 ENSG00000285379 PMC4401249__F4 DIANA miRPath analysis of target genes for miRNAs upregulated in AD blood ENSG00000005339 ENSG00000166501 ENSG00000178719 ENSG00000120251 PMC8635864__F3 To B (Bone Morphogenic Protein-2) or Not to B (Bone Morphogenic Protein-2): Mesenchymal Stem Cells May Explain the Protein’s Role in Osteosarcomagenesis ENSG00000154342 ENSG00000170365 ENSG00000281324 ENSG00000162337 ENSG00000242252 ENSG00000134982 ENSG00000162551 ENSG00000291837 ENSG00000168036 PMC8635864__F1 To B (Bone Morphogenic Protein-2) or Not to B (Bone Morphogenic Protein-2): Mesenchymal Stem Cells May Explain the Protein’s Role in Osteosarcomagenesis ENSG00000170365 ENSG00000137834 ENSG00000242252 ENSG00000162551 ENSG00000291837 ENSG00000108821 PMC8301038__F2 Redox Regulation of Lipid Mobilization in Adipose Tissues ENSG00000086991 PMC9365139__F4 The effects of ATRA treatment of hyperoxic A549 cells ENSG00000142192 PMC3579143__F8 The regulatory role of IRAK-M in TLR-IL-1R signalling ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC10313199__F3 Advances in epigenetic modifications of autophagic process in pulmonary hypertension ENSG00000094631 ENSG00000171720 ENSG00000150907 ENSG00000198793 ENSG00000061273 ENSG00000196591 ENSG00000096717 ENSG00000163517 ENSG00000057663 ENSG00000108840 PMC7337964__F9 Expression profile of genes in Hepatic fibrosis pathway for Pre_S cohort ENSG00000230930 ENSG00000164761 ENSG00000109320 ENSG00000117298 ENSG00000027697 ENSG00000110324 ENSG00000171791 ENSG00000112715 ENSG00000196739 ENSG00000066468 ENSG00000292234 ENSG00000095739 ENSG00000128052 ENSG00000141753 ENSG00000291748 ENSG00000084636 ENSG00000163734 ENSG00000184371 ENSG00000169429 ENSG00000136869 ENSG00000108821 ENSG00000115461 ENSG00000026103 PMC8064355__F7 Schematic illustrating the suppressive effect of 6M3HSC (compound 3) against the RAGE-RAGE ligand signaling pathway ENSG00000116641 ENSG00000070831 ENSG00000163914 ENSG00000189403 ENSG00000172936 ENSG00000166278 ENSG00000150455 ENSG00000184216 PMC5464971__F7 “Tissue Development, Cardiovascular System Development and Function, Organismal Development.” This was the top most associated network according to IPA core analysis of the TM gene input set which included the microarray study by Fan et al ENSG00000110711 ENSG00000170365 ENSG00000152661 ENSG00000108179 ENSG00000038427 ENSG00000111341 ENSG00000152377 ENSG00000104332 ENSG00000197467 ENSG00000169715 ENSG00000137801 PMC8762193__F1 Impaired JAK-STAT pathway signaling in leukocytes of the frail elderly ENSG00000111537 ENSG00000115415 ENSG00000168610 PMC5798893__F7 Dual roles of endothelial FGF-2–FGFR1–PDGF-BB and perivascular FGF-2–FGFR2–PDGFRB signaling pathways in tumor vascular remodeling ENSG00000066468 ENSG00000173599 ENSG00000134853 ENSG00000077782 PMC2219351__F1 Gluten affects epithelial differentiation-associated genes in small intestinal mucosa of coeliac patients ENSG00000077044 ENSG00000214827 ENSG00000168036 ENSG00000146648 PMC7141786__F1 Proposed model for the molecular events and mechanisms underlying the protection of autophagy against alcoholic liver disease ENSG00000158828 ENSG00000112561 PMC2323197__F1 Immunosuppression in islet transplantation ENSG00000100385 PMC7904922__F6 Photoreceptor metabolic reprogramming: current understanding and therapeutic implications ENSG00000125166 ENSG00000065833 ENSG00000172005 ENSG00000115419 PMC7904922__F4 Photoreceptor metabolic reprogramming: current understanding and therapeutic implications ENSG00000077463 PMC9498834__F2 Exploring the recent trends in perturbing the cellular signaling pathways in cancer by natural products ENSG00000135547 ENSG00000137845 PMC2842525__F2 IFNA signal transduction ENSG00000105397 ENSG00000115415 PMC11610372__F7 Mechanism diagram of berberine acting on tuft cells to relieve colitis ENSG00000070985 ENSG00000166090 PMC12125784__F6 Working model ENSG00000215021 ENSG00000162600 PMC8424144__F6 How Kcnma1 regulates bone formation through Wnt/Beta-catenin signaling ENSG00000134982 ENSG00000168036 PMC6987096__F8 Schematic diagram that depicts platelet-induced estrogen biosynthesis in endometriosis ENSG00000203859 ENSG00000105698 ENSG00000160741 ENSG00000158050 PMC9929508__F3 Microgravity and immune cells ENSG00000149311 ENSG00000175054 ENSG00000076662 PMC2885101__F2 PI3K/Akt signaling pathway ENSG00000002330 PMC3659082__F7 Insulin/IGF-1 Signaling, including Class II/III PI3Ks, Beta-Arrestin and SGK-1, Is Required in C. elegans to Maintain Pharyngeal Muscle Performance during Starvation ENSG00000133958 PMC8210242__F4 Genome instability and pressure on non-homologous end joining drives chemotherapy resistance via a DNA repair crisis switch in triple negative breast cancer ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000051180 ENSG00000139618 PMC4506602__F4 Chemical–protein interactions related to the VEGF signaling pathway ENSG00000120910 ENSG00000132906 ENSG00000170890 ENSG00000188257 ENSG00000276870 ENSG00000112715 ENSG00000121879 ENSG00000073756 ENSG00000127472 PMC6378284__F6 WWOX controls TGFB, Hyal-2, and Wnt signaling pathways that cross talks with the Hippo signaling ENSG00000004975 ENSG00000126016 ENSG00000186575 ENSG00000134982 ENSG00000136997 ENSG00000068001 ENSG00000150457 ENSG00000131023 PMC9709458__F1 T cell function by protein S-acylation ENSG00000213658 ENSG00000167323 ENSG00000134982 ENSG00000010810 ENSG00000124181 ENSG00000026103 PMC6378284__F4 A schematic illustration of YAP/TAZ regulation of TE and ICM specification in preimplantation embryo ENSG00000165556 ENSG00000107485 PMC6796845__F3 Core molecular mechanism of non-apoptotic regulated cell death ENSG00000143799 ENSG00000278718 ENSG00000104365 ENSG00000161905 ENSG00000151012 ENSG00000116044 ENSG00000070831 ENSG00000137275 ENSG00000156709 ENSG00000127666 ENSG00000079999 ENSG00000167468 ENSG00000111684 ENSG00000168404 ENSG00000285379 ENSG00000247077 PMC6796845__F2 Extrinsic and intrinsic apoptosis ENSG00000132906 ENSG00000120868 ENSG00000171791 ENSG00000168040 ENSG00000064012 ENSG00000115317 PMC6345610__F3 Illustration of the role of FUNDC1-related MAMs under physiological conditions ENSG00000069509 ENSG00000214253 PMC4278244__F7 Model representing that Wnt/planar cell polarity signaling contributes to the association between pericytes and developing blood vessels via the Wnt5a-Fzd7-cdc42 axis ENSG00000070831 ENSG00000173599 ENSG00000171759 PMC6378284__F2 Mammalian Hippo pathway signaling ENSG00000186575 ENSG00000144560 ENSG00000150457 ENSG00000131023 PMC8135154__F1 Interactions among mTORC, AMPK and SIRT: a computational model for cell energy balance and metabolism ENSG00000177169 ENSG00000105835 ENSG00000278488 ENSG00000239282 ENSG00000096717 PMC6667643__F2 Microenvironmental Regulation of Tumor Progression and Therapeutic Response in Brain Metastasis ENSG00000101751 ENSG00000184371 ENSG00000158825 ENSG00000168610 ENSG00000122194 PMC3502787__F1 General features of the HER family ENSG00000002330 ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000198793 PMC6453741__F4 Functional role of CLDN1 in signal transduction and EMT in liver disease ENSG00000087245 PMC5644891__F1 The leptin/melanocortin pathway ENSG00000112246 ENSG00000115138 ENSG00000166603 PMC5581966__F1 The auto-immune attack to the beta-cells in Type 1 diabetes mellitus ENSG00000111537 ENSG00000115415 ENSG00000102871 ENSG00000134982 ENSG00000172936 ENSG00000168040 ENSG00000175104 ENSG00000127191 ENSG00000184216 ENSG00000026103 PMC5154833__F1 Therapeutic Relevance of mTOR Inhibition in Murine Succinate Semialdehyde Dehydrogenase Deficiency (SSADHD), a Disorder of GABA Metabolism ENSG00000276559 ENSG00000139549 PMC3065553__F5 Metabolic pathway for pitavastatin ENSG00000171234 PMC8879554__F2 Network-Assisted Systems Biology Analysis of the Mitochondrial Proteome in a Pre-Clinical Model of Ischemia, Revascularization and Post-Conditioning ENSG00000100412 ENSG00000105953 ENSG00000091140 PMC5804098__F4 Pharmacologic Reprogramming Designed to Induce a Warburg Effect in Porcine Fetal Fibroblasts Alters Gene Expression and Quantities of Metabolites from Conditioned Media Without Increased Cell Proliferation ENSG00000092621 ENSG00000135069 ENSG00000078237 ENSG00000146733 PMC7599793__F1 Summary of Wnt/Beta-catenin, Hedgehog and hypoxia inducible factor (HIF) pathways and their downstream mediators in the liver ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000288335 ENSG00000168036 ENSG00000100744 ENSG00000106546 ENSG00000134086 ENSG00000106571 ENSG00000125398 ENSG00000164690 ENSG00000163501 ENSG00000276799 PMC5445595__F3 T cell gene expression analyses of T cells from sargramostim-treated or placebo-treated PD patients ENSG00000283934 ENSG00000140968 ENSG00000137265 ENSG00000164938 ENSG00000164399 ENSG00000137507 ENSG00000112378 ENSG00000162892 ENSG00000132170 ENSG00000026103 PMC6172014__F1 Fibroblast growth factor receptor (FGFR) structure, FGFR signaling, and specificity of the FGF–FGFR interaction ENSG00000125538 PMC8588006__F4 Polyphenols Targeting MAPK Mediated Oxidative Stress and Inflammation in Rheumatoid Arthritis ENSG00000174125 ENSG00000172936 PMC12058791__F2 Natural products target ROS, P53, mTOR, NFKB, Beta-catenin and other signaling pathways to regulate apoptosis and play a role in intervening CRC ENSG00000198793 ENSG00000168036 PMC12058791__F1 Action of natural product-targeted modulation of PCD for the treatment of CRC ENSG00000278718 ENSG00000177169 ENSG00000110497 ENSG00000162711 ENSG00000123395 ENSG00000083290 ENSG00000126775 ENSG00000137275 ENSG00000198793 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC3676112__F7 Translation regulation of the mTOR signaling pathway and translation process ENSG00000110700 ENSG00000106682 ENSG00000265681 ENSG00000104131 ENSG00000157764 ENSG00000120705 ENSG00000164587 ENSG00000198793 ENSG00000089157 ENSG00000167658 ENSG00000130811 ENSG00000164327 ENSG00000083845 PMC12026011__F1 Pyrimidine synthesis pathway including the two process of pyrimidine nucleotides synthesis: the novo pathway and the salvage pathway ENSG00000158825 ENSG00000102967 ENSG00000084774 ENSG00000254550 PMC7007431__F1 Serine–glycine-one-carbon metabolism: vulnerabilities in MYCN-amplified neuroblastoma ENSG00000284320 ENSG00000128272 ENSG00000100714 ENSG00000092621 ENSG00000135069 ENSG00000146733 ENSG00000109670 PMC7710720__F3 Sortilin and its soluble form (sSortilin) in colorectal cancer ENSG00000291971 ENSG00000166278 PMC10040131__F7 PHF6 recruits BPTF to promote HIF-dependent pathway and progression in YAP-high breast cancer ENSG00000167772 ENSG00000171634 ENSG00000156531 ENSG00000112715 PMC7710720__F2 Neurotensin pathway in digestive cancers and clinical applications: an overview ENSG00000070831 ENSG00000291971 ENSG00000163914 ENSG00000101188 PMC6721562__F3 Direct and indirect epigenetic control of cellular metabolism ENSG00000134086 ENSG00000198793 ENSG00000159399 PMC10517567__F8 Activation of CTNNB1 by deubiquitinase UCHL3-mediated stabilization facilitates bladder cancer progression ENSG00000004975 ENSG00000112576 ENSG00000107404 ENSG00000138795 ENSG00000156076 ENSG00000134982 ENSG00000175592 ENSG00000168036 ENSG00000118971 ENSG00000065717 ENSG00000078747 ENSG00000177606 ENSG00000136997 PMC535924__F3 Molecular events shown by associated predicates ENSG00000169047 PMC8702371__F3 Precision Nutrition Algorithm for Cancer ENSG00000134982 ENSG00000121879 PMC3342359__F2 Autophagy induction by TLR stimulation ENSG00000172936 ENSG00000136869 PMC12058791__F4 Natural products play a role in intervening in CRC by targeting signalling pathways such as Nrf2, GPX4, NLRP3, RIPK1, and RIPK3 and regulating different forms of cell death mechanisms such as Ferroptosis, Pyroptosis and Necroptosis ENSG00000278718 ENSG00000162711 ENSG00000137275 ENSG00000163568 ENSG00000167468 ENSG00000091592 ENSG00000091106 ENSG00000168040 ENSG00000168404 ENSG00000115107 ENSG00000285379 PMC3342359__F1 Three types of autophagy and cellular and molecular events in an autophagic pathway ENSG00000152348 ENSG00000144848 ENSG00000145782 PMC12058791__F3 Natural products target ROS, PI3K/AKT, AMPK, and LC3 signaling pathways to regulate autophagy and play a role in intervening in CRC ENSG00000177169 ENSG00000198793 ENSG00000144848 PMC5824384__F1 Role and mechanism of Twist1 in renal, pulmonary and skin fibrosis ENSG00000141867 ENSG00000168283 ENSG00000081041 ENSG00000107562 ENSG00000042832 ENSG00000168036 PMC3410437__F2 KEGG pathway of the renin-angiotensin system ENSG00000064601 ENSG00000138792 ENSG00000100448 ENSG00000123213 ENSG00000196549 ENSG00000130234 ENSG00000180772 ENSG00000143839 ENSG00000163751 ENSG00000113441 PMC7555423__F7 G Protein-Coupled Estrogen Receptor Mediates Cell Proliferation through the cAMP/PKA/CREB Pathway in Murine Bone Marrow Mesenchymal Stem Cells ENSG00000123374 ENSG00000105810 PMC7804500__F4 PPI network of the 37 enriched genes from KEGG pathway analysis by Cytoscape ENSG00000019991 ENSG00000087245 ENSG00000105329 ENSG00000070831 ENSG00000109320 ENSG00000171791 ENSG00000112715 ENSG00000007171 ENSG00000132170 ENSG00000149311 ENSG00000108691 ENSG00000111537 ENSG00000170458 ENSG00000125538 ENSG00000136869 ENSG00000100985 ENSG00000026103 ENSG00000164342 PMC6773509__F2 Toll-like receptor signaling – general features of the canonical pathway ENSG00000134070 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC3826519__F8 Deregulated genes upon miR-10b overexpression in FaDu cell line ENSG00000102230 ENSG00000104499 ENSG00000153179 ENSG00000284774 ENSG00000125872 ENSG00000134438 ENSG00000291928 ENSG00000176871 ENSG00000163792 ENSG00000077800 ENSG00000106331 ENSG00000071564 ENSG00000172809 ENSG00000142910 ENSG00000188910 ENSG00000136997 ENSG00000010030 ENSG00000135363 ENSG00000136758 ENSG00000125861 ENSG00000125650 PMC8745479__F1 Relevance of a Novel Circuit-Level Model of Episodic Memories to Alzheimer’s Disease ENSG00000070831 ENSG00000173406 PMC8434408__F4 Nanoparticle-Encapsulated Camptothecin: Epigenetic Modulation in DNA Repair Mechanisms in Colon Cancer Cells ENSG00000090432 ENSG00000149311 ENSG00000012048 ENSG00000083093 ENSG00000084093 ENSG00000154920 ENSG00000197299 ENSG00000051180 ENSG00000139351 ENSG00000138385 ENSG00000139618 PMC8434408__F3 Nanoparticle-Encapsulated Camptothecin: Epigenetic Modulation in DNA Repair Mechanisms in Colon Cancer Cells ENSG00000109674 ENSG00000292286 ENSG00000105486 ENSG00000132646 ENSG00000139372 ENSG00000129071 ENSG00000005381 ENSG00000177084 PMC3365728__F9 RANKL-induced actin ring organization in mature OCs ENSG00000291971 ENSG00000175104 PMC5555796__F2 Metabolic Disorder Dysfunction in Parkinson’s Disease: Bioenergetics, Redox Homeostasis and Central Carbon Metabolism ENSG00000143799 ENSG00000180210 ENSG00000131473 ENSG00000173599 ENSG00000158828 ENSG00000105953 ENSG00000112992 ENSG00000116761 ENSG00000115419 PMC5647101__F2 The co-expressing network of differentially expressed lncRNAs and mRNAs ENSG00000169594 ENSG00000128713 ENSG00000121552 ENSG00000196754 ENSG00000085274 ENSG00000183878 ENSG00000165891 ENSG00000163202 ENSG00000171444 ENSG00000188508 ENSG00000072274 ENSG00000145777 ENSG00000186847 ENSG00000175193 ENSG00000163964 ENSG00000153802 ENSG00000274089 ENSG00000171759 ENSG00000163872 ENSG00000140022 ENSG00000113448 ENSG00000189001 ENSG00000121742 PMC8434408__F5 Nanoparticle-Encapsulated Camptothecin: Epigenetic Modulation in DNA Repair Mechanisms in Colon Cancer Cells ENSG00000113318 ENSG00000132646 ENSG00000095002 ENSG00000138385 ENSG00000122512 PMC10758489__F1 Metabolic reprogramming in the tumor microenvironment: unleashing T cell stemness for enhanced cancer immunotherapy ENSG00000198793 ENSG00000116984 PMC6395542__F2 Dysregulated cholesterol homeostasis drives inflammasome activation ENSG00000162711 ENSG00000110921 ENSG00000163568 ENSG00000160179 PMC4712465__F1 Scheme showing role of pro and anti-inflammatory bioactive lipids in IBD ENSG00000189403 ENSG00000113520 PMC8006293__F9 Depletion of CX3CR1 leads to increased activation of the necrosome in PMNs ENSG00000163464 ENSG00000137033 ENSG00000203710 ENSG00000189403 ENSG00000136869 ENSG00000168404 ENSG00000285379 PMC3859188__F4 Pancreatic cancer initiation pathway for simulation setting (III) ENSG00000132906 ENSG00000117020 ENSG00000017797 ENSG00000002330 ENSG00000109320 ENSG00000196455 ENSG00000006451 ENSG00000213341 ENSG00000169032 ENSG00000062485 PMC5214937__F2 Proposed T ENSG00000239732 ENSG00000088888 ENSG00000172936 ENSG00000164342 PMC2659383__F3 SHH signaling pathway components that have been employed in the production of genetically engineered mouse models ENSG00000136997 ENSG00000164690 ENSG00000128602 PMC5884276__F1 Characteristic enzymes for the synthesis of isopentenyl diphosphate (IPP)/dimethylallyl diphosphate (DMAPP) and the formation of the isoprenoid diphosphate chain ENSG00000197429 PMC9521228__F2 Successful use of eculizumab for treatment of thrombotic microangiopathy in pediatric acute SARS-CoV2 infection and multisystem inflammatory syndrome in children ENSG00000009724 ENSG00000288512 ENSG00000166278 ENSG00000182326 PMC2958907__F1 Web-accessible DC pathway navigator ENSG00000104237 ENSG00000107201 ENSG00000150455 ENSG00000127191 PMC4216593__F8 Although distal 11q copy number loss, from band 11q14 to 11qter has been reported in many types of tumors, its significance had not been investigated until our previous study () ENSG00000149311 ENSG00000175054 ENSG00000149554 ENSG00000183765 PMC7472658__F6 Clinical implications of PTEN loss in prostate cancer ENSG00000169047 ENSG00000198793 ENSG00000164327 PMC4252583__F3 HDL and Cognition in Neurodegenerative Disorders PMC7600430__F7 Schematic diagram illustrating the proposed mechanism of (−)-agelamide D-mediated radiosensitization in HCC ENSG00000128272 ENSG00000144895 PMC11733248__F2 Current therapeutic targets in gastric cancer and GEJ adenocarcinoma ENSG00000198793 PMC4590620__F4 Alcohol’s effects on fibrogenic pathways in hepatic stellate cells (HSCs) ENSG00000095739 ENSG00000170458 ENSG00000136869 PMC7400404__F11 Complexin 2 in green box was mapped onto the synaptic vesicle cycle pathway (04721) generated by KEGG PATHWAY (Organism: Danio rerio) ENSG00000102003 PMC4590620__F2 Alcohol’s effects on pro-inflammatory pathways in liver macrophages (i.e., Kupffer cells) ENSG00000170458 ENSG00000125538 ENSG00000136869 PMC5430631__F6 Distribution of Turkish galls target proteins on the compressed UC pathway ENSG00000134982 ENSG00000049768 PMC7329534__F8 Pathway analysis A) Pathway analysis for upregulated (a) and downregulated (b) miRNAs and their respective mRNA targets ENSG00000167601 ENSG00000140992 ENSG00000113763 ENSG00000137713 ENSG00000221866 ENSG00000175866 ENSG00000120875 ENSG00000134215 ENSG00000169047 ENSG00000164327 ENSG00000070886 ENSG00000123124 ENSG00000204262 ENSG00000163882 ENSG00000107263 ENSG00000077254 ENSG00000077782 ENSG00000136040 ENSG00000173406 ENSG00000130827 ENSG00000114554 ENSG00000181852 ENSG00000167578 ENSG00000189056 ENSG00000106299 ENSG00000137872 ENSG00000167552 ENSG00000154016 ENSG00000139219 ENSG00000063245 ENSG00000069869 ENSG00000164078 ENSG00000127824 ENSG00000133961 ENSG00000130508 ENSG00000146648 ENSG00000075213 ENSG00000292254 ENSG00000187955 ENSG00000164086 ENSG00000070087 ENSG00000019991 ENSG00000140564 ENSG00000280962 ENSG00000145147 ENSG00000106397 ENSG00000135333 ENSG00000101266 ENSG00000169032 ENSG00000112715 ENSG00000166068 ENSG00000089159 ENSG00000114738 ENSG00000151914 ENSG00000171105 ENSG00000259207 ENSG00000108861 ENSG00000090776 ENSG00000143933 ENSG00000114573 ENSG00000004399 ENSG00000105053 ENSG00000100320 ENSG00000196961 ENSG00000117020 ENSG00000144749 ENSG00000124882 ENSG00000160867 ENSG00000116106 ENSG00000173898 ENSG00000291748 ENSG00000183020 ENSG00000149554 ENSG00000171608 PMC8027215__F4 Key genes and metabolic pathways in Lokiarchaeota ENSG00000122971 ENSG00000127948 ENSG00000102977 PMC5829268__F2 Schematic demonstration of TCR signaling ENSG00000291603 ENSG00000213658 ENSG00000177606 PMC4648381__F2 MGMT and other DNA repair mechanisms deal with DNA damage produced by the alkylating agent TMZ in cancer cells ENSG00000291803 ENSG00000170430 ENSG00000105656 ENSG00000227345 PMC11658435__F7 Adipose-derived stem cell exosomes attenuates myofibroblast transformation via inhibiting autophagy through TGFB/Smad2 axis in oral submucosal fibrosis PMC10778515__F6 The Rap1 signaling pathway ENSG00000128052 PMC9359062__F1 Anaplastic lymphoma kinase-special immunity and immunotherapy ENSG00000161955 ENSG00000123685 ENSG00000019991 ENSG00000198793 ENSG00000137265 ENSG00000168610 PMC6456408__F7 Type I IFN signaling and production in Mtb-infected cells ENSG00000213928 ENSG00000115415 PMC7919457__F3 Gene fusions in pancreatic cancer ENSG00000157764 ENSG00000107104 ENSG00000065361 ENSG00000047936 ENSG00000121440 ENSG00000066468 ENSG00000138757 ENSG00000125844 ENSG00000114268 ENSG00000113361 ENSG00000122779 ENSG00000143924 ENSG00000187955 PMC7570361__F1 Biosynthesis of steroids in mammals ENSG00000277893 ENSG00000203859 PMC8131524__F1 Exploring the Gut-Brain Axis for the Control of CNS Inflammatory Demyelination: Immunomodulation by Bacteroides fragilis’ Polysaccharide A ENSG00000134982 ENSG00000172936 ENSG00000136869 PMC5916949__F6 A schematic depicting the potential involvement of MALAT1 in regulating inflammation through epigenetic mechanisms in diabetic retinopathy ENSG00000074266 ENSG00000178691 PMC4211625__F1 Tyrosine phosphatase SHP2 is required for the proper timing of neurogenesis and gliogenesis and the balance between them during CNS development ENSG00000242689 ENSG00000115415 ENSG00000136997 ENSG00000128342 ENSG00000168610 PMC8699088__F2 Senescent Cells in Cancer: Wanted or Unwanted Citizens ENSG00000164430 ENSG00000285109 ENSG00000198793 ENSG00000115594 PMC6047270__F1 Cell cycle arrest induced fibrosis ENSG00000149311 ENSG00000175054 ENSG00000105329 ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC7311088__F1 Synthesis of Fluorinated Amide Derivatives via a Radical N-Perfluoroalkylation–Defluorination Pathway ENSG00000074800 PMC6167191__F5 Dendritic Spine Elimination: Molecular Mechanisms and Implications ENSG00000163464 ENSG00000153208 ENSG00000116106 ENSG00000145794 PMC11039819__F2 Interplay between autophagy and cGAS-STING signaling and its implications for cancer ENSG00000171855 ENSG00000183735 ENSG00000164430 PMC1483059__F10 Peculiar structure of the juxtanuclear actin network ENSG00000070831 ENSG00000291971 PMC3763461__F1 Hypothetical model explaining the pathway through which mutated htt (mhtt) causes OMM permeabilization ENSG00000002330 PMC6584619__F8 mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGFB1––induced collagen biosynthesis ENSG00000128272 ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC8392056__F1 Molecularly Targeted Therapies for Gastric Cancer. State of the Art ENSG00000019991 ENSG00000198793 ENSG00000146648 PMC7997471__F5 Proposed mechanism is depicting the effect of IMP inhibiting inflammatory effects ENSG00000170458 ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000168610 ENSG00000079999 PMC4739752__F1 Repression of DNA-damage signaling pathways at telomeres ENSG00000143799 ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000101751 ENSG00000163961 ENSG00000116670 ENSG00000080345 ENSG00000051180 ENSG00000128513 PMC3924780__F1 Scaffolding Proteins: Not Such Innocent Bystanders ENSG00000281324 ENSG00000168036 ENSG00000166851 PMC3432564__F2 Transmembrane CLRs involved in antifungal immunity and their intracellular signaling pathways ENSG00000187796 ENSG00000172936 PMC6167191__F7 Dendritic Spine Elimination: Molecular Mechanisms and Implications ENSG00000002330 ENSG00000198576 PMC3518628__F1 Interplay between Wnt/Beta-catenin signaling and HIV: Virologic and biologic consequences in the CNS ENSG00000134982 ENSG00000168036 ENSG00000165282 PMC3252742__F4 Apoptotic pathway in cardiac myocytes ENSG00000132906 ENSG00000002330 ENSG00000164305 PMC3518628__F3 Interplay between Wnt/Beta-catenin signaling and HIV: Virologic and biologic consequences in the CNS ENSG00000101751 ENSG00000111537 ENSG00000168036 ENSG00000168646 PMC11760468__F1 Ras signaling and its involvement in myeloid malignancies ENSG00000122025 ENSG00000033327 ENSG00000002330 ENSG00000117400 ENSG00000198793 ENSG00000168036 ENSG00000196712 PMC6317740__F1 Dishevelled: a masterful conductor of complex Wnt signals ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000163914 ENSG00000168036 PMC4573074__F1 Regulation of autophagy.Notes: mTOR is one of the most important regulators of autophagy ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000144848 ENSG00000171791 ENSG00000145782 ENSG00000057663 PMC4056054__F1 Co-culture with M38 melanoma upregulate interferon signalling pathways ENSG00000178860 ENSG00000111537 ENSG00000125347 PMC3084393__F10 Proposed diagram for Alpha-mangostin-induced apoptosis in COLO 205 cells ENSG00000104081 ENSG00000026103 PMC4013479__F1 A simplified working model of the c-di-GMP signaling pathway in B ENSG00000160214 ENSG00000159399 PMC7353358__F2 Phytochemicals activate the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway ENSG00000106546 ENSG00000079999 PMC4534795__F12 Selective post-translational processing of transcription factor Nrf1 yields distinct isoforms that dictate its ability to differentially regulate gene expression ENSG00000166278 ENSG00000106459 PMC6888825__F7 Proposed transcriptional regulatory system for VA and SA catabolism in Sphingobium sp ENSG00000105486 ENSG00000174197 PMC7497066__F1 Frequent mutations in positive (green) and negative (red) regulators of the NF‐KB pathway in MM ENSG00000104856 ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000082512 ENSG00000111321 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000127191 PMC2741634__F2 How location governs Toll like receptor signaling ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC11909974__F10 Integrative analysis of transcriptome and metabolome reveal molecular mechanism of tolerance to salt stress in rice ENSG00000133116 ENSG00000172005 PMC9125221__F6 Identification of Candidate Genes Associated With Tolerance to Apple Replant Disease by Genome-Wide Transcriptome Analysis ENSG00000205517 PMC6738915__F6 Protective effect of lactobacillus plantarum on alcoholic liver injury and regulating of keap-Nrf2-ARE signaling pathway in zebrafish larvae ENSG00000178573 ENSG00000100387 ENSG00000079999 PMC7393266__F2 Major anti-tumor mechanisms of EGFR monoclonal antibodies ENSG00000188486 ENSG00000123374 ENSG00000146648 PMC3616148__F2 Roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability ENSG00000132646 ENSG00000162607 ENSG00000070950 ENSG00000130997 PMC7359322__F6 Heat map and DEGs expression profiles of genes associated with phenylpropanoid biosynthetic pathway, (B) heat map showing the different expression profiles of genes involved in the terpene biosynthesis pathway ENSG00000110921 ENSG00000197429 ENSG00000167508 ENSG00000082212 ENSG00000084774 PMC3616148__F3 Roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability ENSG00000012061 ENSG00000154920 ENSG00000144554 ENSG00000188827 ENSG00000276787 PMC6215570__F6 Akt/mTOR pathway and regulatory effects of galangin and pinocembrin on the phosphorylation of key proteins ENSG00000198793 PMC3266773__F10 CD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progression ENSG00000139193 ENSG00000138795 ENSG00000159216 ENSG00000186716 ENSG00000168036 ENSG00000154310 ENSG00000112715 ENSG00000127191 PMC3762088__F2 Regulation of autophagy by oncogenes and tumor suppressors ENSG00000171791 PMC5700962__F8 Parkinson disease pathway(red, up-regulated) ENSG00000180210 ENSG00000115317 PMC5700962__F7 Six genes are enriched in the top 2 significant pathways(red, up-regulated) ENSG00000157404 ENSG00000135960 ENSG00000138071 PMC7450308__F1 Increasing ROS triggers mitochondrial damage related to ferroptosis under cysteine starvation ENSG00000167468 PMC2822975__F1 Asbestos has pleiotropic effects on cell signaling pathways ENSG00000102871 ENSG00000198793 ENSG00000146648 PMC9475360__F2 KRAS as a Key Oncogene in the Clinical Precision Diagnosis and Treatment of Pancreatic Cancer ENSG00000198793 ENSG00000131023 PMC9475360__F1 KRAS as a Key Oncogene in the Clinical Precision Diagnosis and Treatment of Pancreatic Cancer ENSG00000198793 ENSG00000115904 PMC10491753__F5 Pictorial model of intracellular redox balance facilitated by compartmentalization of amino acid biosynthesis enzymes within optimally sized peroxisomes PMC5771206__F6 Intramuscular fat metabolism ENSG00000157184 ENSG00000151365 PMC10242330__F2 Autophagy: A challengeable paradox in cancer treatment ENSG00000110497 ENSG00000126775 ENSG00000171791 PMC7646705__F1 Schematic outline of lipid oxidation and impaired lipoprotein metabolism in psoriasis ENSG00000130164 ENSG00000005421 ENSG00000160179 PMC8972277__F5 Aspirin attenuates liver fibrosis by suppressing TGFB1/Smad signaling PMC6444613__F1 Metabolic pathway of propionyl-CoA and methylmalonyl-CoA ENSG00000124275 ENSG00000168288 ENSG00000142273 ENSG00000119912 ENSG00000168216 PMC4453439__F1 The signalling pathways implicated in fusion-positive ARMS progression ENSG00000009709 ENSG00000160867 ENSG00000150907 ENSG00000135903 ENSG00000140443 PMC3088722__F6 Latent Pro-Survival Function for the Mir-290-295 Cluster in Mouse Embryonic Stem Cells ENSG00000010803 ENSG00000129355 ENSG00000146143 ENSG00000150457 ENSG00000198300 ENSG00000148935 ENSG00000124762 ENSG00000115760 ENSG00000113328 ENSG00000103479 ENSG00000291470 ENSG00000121068 ENSG00000134574 ENSG00000135446 ENSG00000164938 ENSG00000113761 ENSG00000149547 ENSG00000102974 PMC7606576__F3 WNK/SPAK/CCC signaling pathway in cell volume homeostasis ENSG00000196632 ENSG00000143867 ENSG00000060237 PMC3672665__F1 Epithelial cancer cell inflammatory response ENSG00000083799 ENSG00000168610 PMC3842443__F2 Molecular Targeted Drugs and Biomarkers in NSCLC, the Evolving Role of Individualized Therapy ENSG00000019991 ENSG00000070831 ENSG00000065361 ENSG00000169047 ENSG00000163914 PMC5987629__F1 Schematic diagram of the heterologous synthesis pathway for the production of geranyl acetate in the engineered S ENSG00000067064 ENSG00000197429 ENSG00000179632 PMC10526800__F3 Diverse Roles of Protein Palmitoylation in Cancer Progression, Immunity, Stemness, and Beyond ENSG00000281324 ENSG00000162337 ENSG00000198793 ENSG00000136026 ENSG00000169174 ENSG00000140443 PMC8557215__F7 Schematic drawing of LPS function in PDAC ENSG00000172936 ENSG00000136869 PMC9133627__F1 Advances on Innate Immune Evasion by Avian Immunosuppressive Viruses ENSG00000213928 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000131323 ENSG00000276561 PMC3071831__F7 Targeted Morphoproteomic Profiling of Ewing's Sarcoma Treated with Insulin-Like Growth Factor 1 Receptor (IGF1R) Inhibitors: Response/Resistance Signatures ENSG00000151702 ENSG00000198793 ENSG00000164327 ENSG00000140443 PMC6328873__F1 State of art of neutrophil extracellular traps in protozoan and helminthic infections ENSG00000136869 ENSG00000005381 PMC7779655__F5 Copper-dependent mechanisms of cancer cell migration and metastasis ENSG00000291971 ENSG00000177556 PMC2749862__F5 Most prominently affected gene network in response to DEX in TM 86 cells ENSG00000029363 ENSG00000186660 ENSG00000114098 ENSG00000114857 PMC7779655__F4 Copper-dependent mechanisms of oncogenic signaling ENSG00000177169 ENSG00000083290 ENSG00000198793 PMC5024694__F1 Simplified model of the canonical Wnt pathway and inhibitors ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC2749862__F6 Most prominently affected gene network in response to FA in TM 93 cells ENSG00000111665 ENSG00000064042 ENSG00000104147 ENSG00000291600 ENSG00000096092 ENSG00000087842 ENSG00000278787 ENSG00000169715 PMC7794785__F5 Activation of MAPK pathways (highlighted in yellow), the guanyl cyclase pathway (highlighted in orange) and nuclear factorKB (highlighted in purple) by the adenosine A1 receptor (A1R) ENSG00000124126 PMC7779655__F1 Cellular copper homeostasis in mammals ENSG00000115318 ENSG00000138131 ENSG00000183513 ENSG00000138495 ENSG00000123191 ENSG00000166260 ENSG00000123454 ENSG00000177556 ENSG00000240230 ENSG00000129038 ENSG00000173992 ENSG00000134013 ENSG00000168275 ENSG00000284194 PMC10836028__F9 Schematic figure showing that melatonin attenuates mechanical trauma-induced hepatic injury by inhibiting IP3R1-mediated MAMs formation via activating the melatonin receptor-ERK1/2-FoxO1 pathway ENSG00000150907 PMC4851740__F3 Schematic model of signaling pathways implicated in tumor cell VM ENSG00000087245 ENSG00000142627 ENSG00000122691 ENSG00000157227 ENSG00000156574 PMC2693232__F2 Unifying model of TGFB signaling in breast epithelium ENSG00000163235 ENSG00000170558 ENSG00000113140 ENSG00000272398 ENSG00000026508 PMC4614799__F1 Driver genetic lesions in papillary thyroid carcinoma ENSG00000198793 PMC7581770__F2 Pathway annotation analysis of AVNFH patient cartilage transcriptomics and RANKL induced osteoclastogenesis transcriptomics ENSG00000104856 ENSG00000228716 ENSG00000065911 ENSG00000070831 ENSG00000198793 ENSG00000072274 ENSG00000103222 ENSG00000105647 ENSG00000173113 ENSG00000169032 ENSG00000145293 ENSG00000164933 ENSG00000138356 ENSG00000120254 ENSG00000100714 ENSG00000056558 ENSG00000168216 ENSG00000119688 ENSG00000100906 ENSG00000090674 ENSG00000151611 ENSG00000132763 ENSG00000127191 ENSG00000023909 ENSG00000110719 ENSG00000076351 ENSG00000143387 ENSG00000274247 ENSG00000110395 ENSG00000137364 ENSG00000168928 ENSG00000004948 ENSG00000162438 ENSG00000168288 ENSG00000107611 ENSG00000185339 ENSG00000182551 ENSG00000037757 ENSG00000070214 ENSG00000116761 PMC6017457__F3 Schematic representation of the unfolded protein response pathway ENSG00000128272 ENSG00000144895 PMC2690394__F2 Molecular targets of natural chemopreventive agents PMC5557355__F7 Increased signaling by the autism-related Engrailed-2 protein enhances dendritic branching and spine density, alters synaptic structural matching, and exaggerates protein synthesis ENSG00000198793 ENSG00000163064 ENSG00000164778 PMC8721012__F5 New Antitumor Direction: Tumor-Specific Endothelial Cells ENSG00000102962 ENSG00000108691 ENSG00000132622 ENSG00000198793 PMC6522317__F2 Unfolding the Role of Calreticulin in Myeloproliferative Neoplasm Pathogenesis ENSG00000151702 ENSG00000117400 PMC8536918__F1 Comprehensive overview of extracellular vesicle proteomics in meningioma: future strategy ENSG00000134982 ENSG00000168036 ENSG00000128602 ENSG00000146648 PMC2627788__F5 Wnt/Beta-catenin signaling pathway in leukemia ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000101115 ENSG00000168036 PMC3314429__F2 miRNA-mediated immune regulation and immunotherapeutic potential in glioblastoma ENSG00000168610 ENSG00000146648 PMC3663800__F8 New Algorithm for Integrated Analysis of miRNA-mRNA Interactions Based on Individual Classification Reveals Insights into Bladder Cancer ENSG00000112242 ENSG00000135446 ENSG00000138798 ENSG00000146648 ENSG00000282899 PMC5154738__F2 Translational Control of Long-Lasting Synaptic Plasticity and Memory ENSG00000169047 ENSG00000198793 ENSG00000164327 PMC7105607__F2 Impact of NFKB on MS animal models ENSG00000104856 ENSG00000105656 PMC7105607__F1 NFKB signaling cascade ENSG00000104856 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC3663800__F7 New Algorithm for Integrated Analysis of miRNA-mRNA Interactions Based on Individual Classification Reveals Insights into Bladder Cancer ENSG00000027075 ENSG00000185634 ENSG00000065675 ENSG00000115904 ENSG00000169032 ENSG00000112992 ENSG00000100485 ENSG00000160691 ENSG00000068028 ENSG00000063176 ENSG00000163558 ENSG00000148082 ENSG00000067606 ENSG00000129946 ENSG00000166501 ENSG00000134853 ENSG00000197943 ENSG00000124181 ENSG00000146648 PMC6558796__F3 Gene network analysis of RNA-Seq data from MDA-MB-231 and OVCAR3 cells ENSG00000182628 ENSG00000137804 ENSG00000123975 ENSG00000134982 ENSG00000131153 ENSG00000157601 ENSG00000185745 ENSG00000196313 ENSG00000166068 ENSG00000145604 ENSG00000132530 ENSG00000152778 ENSG00000134321 ENSG00000105397 ENSG00000024526 ENSG00000130775 ENSG00000132646 ENSG00000112984 ENSG00000168310 ENSG00000111331 ENSG00000114209 ENSG00000134690 ENSG00000196116 PMC4227170__F2 CD147 plays an important role in a variety of cells and tissues regardless of health or disease ENSG00000145321 ENSG00000026508 ENSG00000118777 ENSG00000146648 PMC11718844__F2 Signaling by IL-23R ENSG00000162594 ENSG00000099901 ENSG00000138378 ENSG00000105397 ENSG00000182568 ENSG00000150907 ENSG00000118515 ENSG00000049768 ENSG00000168610 PMC6381934__F1 Metabolic pathways of 1,25(OH)2D and 27HC synthesis ENSG00000111012 ENSG00000019186 ENSG00000186104 ENSG00000135929 PMC11718844__F5 Key approved pharmacological agents for the IL-23R pathway ENSG00000162594 ENSG00000105397 PMC8052535__F1 Proteolysis and inflammation of the kidney glomerulus ENSG00000039537 ENSG00000113600 ENSG00000291559 ENSG00000288512 ENSG00000244731 ENSG00000166278 ENSG00000182326 ENSG00000236625 PMC8439382__F1 The UPR Pathway in the Pathophysiology and Treatment of Bipolar Disorder ENSG00000128272 ENSG00000144895 PMC3645655__F3 P53 and BRCA regulation of DNA repair represents a central component of altered cellular function in serous ovarian cancer ENSG00000164796 ENSG00000145020 ENSG00000139618 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000136997 ENSG00000132698 ENSG00000051180 ENSG00000165323 ENSG00000139687 ENSG00000196712 ENSG00000172201 PMC5433029__F1 Hypothetical schematic of the physiological and pathophysiological roles of Notch signalling in articular cartilage ENSG00000115602 ENSG00000154736 ENSG00000168214 ENSG00000148400 ENSG00000137845 PMC7651136__F4 Deciphering UV-induced DNA Damage Responses to Prevent and Treat Skin Cancer ENSG00000149311 ENSG00000175054 ENSG00000123374 PMC5700962__F9 Breast cancer pathway(red, up-regulated) ENSG00000157404 ENSG00000169291 ENSG00000134982 ENSG00000135446 ENSG00000146648 PMC3217209__F1 Insulin Resistance, Hyperglycemia, and Atherosclerosis ENSG00000198793 ENSG00000087842 ENSG00000162692 PMC7651136__F7 Deciphering UV-induced DNA Damage Responses to Prevent and Treat Skin Cancer ENSG00000175054 ENSG00000108582 ENSG00000189403 ENSG00000136869 ENSG00000146648 PMC7651136__F9 Deciphering UV-induced DNA Damage Responses to Prevent and Treat Skin Cancer ENSG00000198793 ENSG00000136997 PMC4735799__F8 Reversible interconversion and maintenance of mammary epithelial cell characteristics by the ligand-regulated EGFR system ENSG00000109321 ENSG00000138798 ENSG00000146648 PMC8590697__F7 Graphical abstract of the mechanism by which cetuximab enhances RSL3-induced ferroptosis by inhibiting the Nrf2/HO-1 axis through the activation of p38 MAPK ENSG00000138798 ENSG00000167468 ENSG00000146648 PMC8704271__F1 Microarray analysis to explore the effect of CXCL12 isoforms in a pancreatic pre-tumor cell model ENSG00000138722 ENSG00000107562 ENSG00000092853 ENSG00000152527 ENSG00000232040 ENSG00000198793 ENSG00000197632 ENSG00000125337 ENSG00000149571 ENSG00000141068 ENSG00000170891 ENSG00000135905 ENSG00000137959 ENSG00000140416 ENSG00000175054 ENSG00000112242 ENSG00000164404 ENSG00000186847 ENSG00000133169 ENSG00000168229 ENSG00000118515 ENSG00000154721 ENSG00000136108 ENSG00000182179 PMC6683007__F7 Molecular mechanisms associated with acylcarnitine expression in substantia nigra 3 days post-TBI ENSG00000189403 ENSG00000136869 ENSG00000151025 PMC8138567__F2 Curcumin as a Potential Treatment for COVID-19 ENSG00000130234 ENSG00000198793 ENSG00000184012 ENSG00000168610 ENSG00000146648 PMC6584345__F4 TRAIL death receptor pathway and its regulation by bioactive peptides ENSG00000130300 ENSG00000168040 PMC6972648__F5 Evidence for a role of protein phosphorylation in the maintenance of the cnidarian–algal symbiosis ENSG00000105392 ENSG00000159461 ENSG00000165280 PMC6584345__F3 STAT3 signaling pathway and its regulation by bioactive peptides ENSG00000169291 ENSG00000198793 ENSG00000168610 PMC8622906__F5 CD40 Pathway and IL-2 Expression Mediate the Differential Outcome of Colorectal Cancer Patients with Different CSF1R c.1085 Genotypes ENSG00000182578 ENSG00000102245 PMC5778467__F7 Biological pathways that engage TDP1 and TDP2 ENSG00000143799 ENSG00000039650 ENSG00000042088 ENSG00000138385 PMC11350665__F7 Main biological pathway responses to acute Cd exposure in oysters ENSG00000143198 ENSG00000169710 ENSG00000002549 PMC6343200__F5 Current Strategies for Elimination of HIV-1 Latent Reservoirs Using Chemical Compounds Targeting Host and Viral Factors ENSG00000136807 ENSG00000174720 ENSG00000185513 ENSG00000141867 ENSG00000101945 ENSG00000173039 ENSG00000185591 ENSG00000143499 ENSG00000146834 PMC8750274__F2 Intricate Interplay between Cell Cycle Regulators and Autophagy in Cancer ENSG00000177169 ENSG00000198382 ENSG00000126775 ENSG00000135446 ENSG00000112561 ENSG00000123374 ENSG00000105810 ENSG00000145782 ENSG00000057663 ENSG00000198925 PMC9545958__F8 LncRNA AK018453 regulates TRAP1/Smad signaling in IL‐17‐activated astrocytes: A potential role in EAE pathogenesis PMC9229972__F3 Network Approaches to Integrate Analyses of Genetics and Metabolomics Data with Applications to Fetal Programming Studies ENSG00000145321 ENSG00000166278 ENSG00000062485 ENSG00000165449 PMC9501218__F5 MLK3 Regulates Inflammatory Response via Activation of AP-1 Pathway in HEK293 and RAW264.7 Cells ENSG00000136869 ENSG00000164342 PMC4107945__F1 RLR signaling pathway is shown ENSG00000183735 ENSG00000088888 ENSG00000143258 ENSG00000121060 PMC3620110__F6 Expression of GATA3 in MDA-MB-231 Triple-negative Breast Cancer Cells Induces a Growth Inhibitory Response to TGFß ENSG00000178999 ENSG00000167513 ENSG00000131747 ENSG00000101057 ENSG00000058091 ENSG00000099860 ENSG00000087586 ENSG00000073111 ENSG00000198056 ENSG00000124762 ENSG00000093009 ENSG00000117724 ENSG00000288210 ENSG00000065328 ENSG00000092470 ENSG00000134057 ENSG00000089685 ENSG00000132646 ENSG00000080839 ENSG00000134690 ENSG00000149503 PMC3944254__F5 Proposed model of hypoxia-induced cellular processes presumably leading to antifolate resistance ENSG00000228716 ENSG00000136877 ENSG00000084774 PMC8820521__F2 Introduction to DOK2 and its Potential Role in Cancer ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC12096540__F1 Key reactions involved in glycerolipid synthesis in plants ENSG00000069482 ENSG00000173599 ENSG00000198670 ENSG00000026103 PMC4384471__F4 Induction of interferon (IFN) and its antagonism by viral proteins ENSG00000164430 ENSG00000088888 ENSG00000276561 PMC8495158__F2 Study on Transorgan Regulation of Intervertebral Disc and Extra-Skeletal Organs Through Exosomes Derived From Bone Marrow Mesenchymal Stem Cells ENSG00000105664 ENSG00000142192 ENSG00000173599 ENSG00000127948 PMC4384471__F2 Interferon (IFN) signaling via the JAK–STAT pathway ENSG00000159128 ENSG00000105397 ENSG00000185436 ENSG00000027697 ENSG00000142166 PMC11989373__F2 AMPK signaling pathway in brown adipocyte thermogenesis PMC6783260__F1 Complement activation triggers neuronal damage PMC3620110__F2 Expression of GATA3 in MDA-MB-231 Triple-negative Breast Cancer Cells Induces a Growth Inhibitory Response to TGFß ENSG00000170365 ENSG00000111859 ENSG00000134363 ENSG00000107485 ENSG00000076706 ENSG00000153317 ENSG00000171604 PMC5065109__F2 Current hypotheses for IFNGamma-mediated effect on NSPC activity.Notes: IFNG binds to the IFNG receptor (IFNGR1 and 2) and activates Janus-activated kinases 1 and 2 and signal transducers and activators of transcription-1 (JAK-STAT1) pathway ENSG00000159128 ENSG00000111537 ENSG00000115415 ENSG00000027697 ENSG00000164690 ENSG00000168610 PMC5682975__F5 Proposed model of IRAK4 regulation of TLR7/8 signaling pathway in human monocytes is shown ENSG00000172936 ENSG00000175104 PMC11240352__F1 Genetic and nongenetic mechanisms of CRC resistance to cetuximab ENSG00000019991 ENSG00000157764 ENSG00000146648 ENSG00000140443 PMC9455954__F9 Comparative Physiological and Transcriptomic Analyses of Two Contrasting Pepper Genotypes under Salt Stress Reveal Complex Salt Tolerance Mechanisms in Seedlings ENSG00000105722 ENSG00000115718 ENSG00000105669 PMC11083860__F8 FGF23/FGFR1cAklotho signalling pathway which mediates phosphorylation of NHERF1 ENSG00000118972 ENSG00000118515 ENSG00000115904 ENSG00000109062 PMC3000288__F1 Schematic representation of the As cycle in the environment and plants ENSG00000090402 ENSG00000173599 ENSG00000103222 ENSG00000023839 PMC7396444__F4 Expression of DEGs involved in the apoptosis and autophagy signaling pathways ENSG00000168040 ENSG00000135116 ENSG00000084774 PMC1974867__F9 Synergistic airway gland mucus secretion in response to vasoactive intestinal peptide and carbachol is lost in cystic fibrosis ENSG00000146469 ENSG00000001626 PMC11240352__F4 Cetuximab mechanism of action and summary of how RAC1 and RAC1B could contribute to the known mechanisms of cetuximab resistance in CRC ENSG00000149968 ENSG00000149269 ENSG00000146648 ENSG00000140443 PMC7569177__F9 Cell Cycle Pathway from the KEGG Pathway hsa04110 ENSG00000145604 ENSG00000132646 ENSG00000115942 ENSG00000123374 ENSG00000164754 ENSG00000277273 ENSG00000166851 ENSG00000117399 PMC6267225__F2 Core analyses network predictions for HBoV-infected CuFi-8 cells ENSG00000184381 ENSG00000144802 ENSG00000111859 ENSG00000150907 ENSG00000116584 ENSG00000158158 ENSG00000137801 PMC9693457__F2 Old and New Facts and Speculations on the Role of the B Cell Receptor in the Origin of Chronic Lymphocytic Leukemia ENSG00000138798 ENSG00000186716 ENSG00000146648 PMC9693457__F1 Old and New Facts and Speculations on the Role of the B Cell Receptor in the Origin of Chronic Lymphocytic Leukemia ENSG00000198793 ENSG00000197943 ENSG00000010671 PMC5553878__F6 Proposed model by which CCR7 regulated NFKB/VEGF pathway and induced angiogenesis in esophageal squamous carcinoma cells ENSG00000126353 ENSG00000112715 ENSG00000150630 PMC9687478__F1 Antiviral Innate Immune Responses in Autoimmunity: Receptors, Pathways, and Therapeutic Targeting ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC6038164__F1 RhoA/ROCK1/LIMK2/Cofilin signaling pathway ENSG00000067900 ENSG00000182541 PMC7223178__F1 Mammalian TLR signaling pathway ENSG00000174123 ENSG00000174125 ENSG00000183735 ENSG00000226275 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC5474286__F1 Schematic representation of the immune cells involved in Mycobacterium tuberculosis infection ENSG00000125538 PMC5915337__F4 Comprehensive proteomic profiling identifies the androgen receptor axis and other signaling pathways as targets of microRNAs suppressed in metastatic prostate cancer ENSG00000109452 ENSG00000148400 ENSG00000134057 ENSG00000115457 ENSG00000291971 ENSG00000135446 ENSG00000132646 ENSG00000169047 ENSG00000284161 ENSG00000051180 ENSG00000078237 PMC4057133__F6 Summary of signaling events leading to PRKD2-dependent induction of senescence in p53wt and p53mut GBM cells ENSG00000135446 ENSG00000123374 ENSG00000105287 PMC4523434__F1 Endoplasmic reticulum quality control in cancer: friend or foe ENSG00000100219 ENSG00000135506 PMC3913938__F7 Suggested mechanisms of synergistic cytotoxicity of [Gem+Clo+Ed] combination in lymphoma cells based on the previously reported data and our present results ENSG00000132906 ENSG00000168040 ENSG00000064012 ENSG00000164305 PMC2233667__F6 Computational and Experimental Analysis of Redundancy in the Central Metabolism of Geobacter sulfurreducens ENSG00000173599 ENSG00000127948 ENSG00000062485 PMC11174978__F3 Understanding Fibrous Tissue in the Effective Healing of Rotator Cuff Injury ENSG00000137673 ENSG00000134982 ENSG00000157227 ENSG00000291748 ENSG00000168036 ENSG00000108821 PMC7751853__F6 Bergenin protects pancreatic beta cells against cytokine-induced apoptosis in INS-1E cells ENSG00000115415 ENSG00000125538 ENSG00000168040 PMC8986524__F3 Molecular mechanisms underlying the emergence of polygenetic antifungal drug resistance in msh2 mismatch repair mutants of Cryptococcus ENSG00000166887 ENSG00000112335 ENSG00000215305 PMC1560097__F3 Light-cycle of rhodopsin PMC4914571__F5 Gene of the month: SMARCB1 ENSG00000094804 ENSG00000136997 ENSG00000168036 PMC8976844__F6 Mechanism graph of the regulatory network and function of miR-30c ENSG00000026508 ENSG00000168036 PMC7987693__F1 TGFB signaling pathways in EMT ENSG00000087245 ENSG00000169554 ENSG00000070831 ENSG00000170558 ENSG00000198793 ENSG00000168036 ENSG00000100985 ENSG00000175104 PMC309045__F1 CRP-dependent (A) and CcpA-dependent (B) carbon catabolite repression pathways and the Ntr regulatory pathway (C) ENSG00000261701 ENSG00000132693 PMC6923180__F6 Schematic diagram of the pathway for OXT inhibition of CRC metastasis ENSG00000108691 PMC6362084__F5 Activated TLR4 signal inhibited by neurosteroids ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC4785873__F3 Alcohol consumption induces global gene expression changes in VTA dopaminergic neurons ENSG00000198839 ENSG00000163463 ENSG00000188976 ENSG00000104221 ENSG00000214753 ENSG00000101811 ENSG00000124193 ENSG00000113068 PMC6798880__F2 Oncogenic KRAS effector pathways ENSG00000167601 ENSG00000183735 ENSG00000144118 ENSG00000198793 PMC8603983__F3 Revisiting cancer hallmarks: insights from the interplay between oxidative stress and non-coding RNAs ENSG00000122378 ENSG00000253352 ENSG00000079999 PMC7300384__F2 Epigenetic and epitranscriptomic pathways depend on metabolism ENSG00000131473 ENSG00000105835 ENSG00000061273 ENSG00000157064 ENSG00000142082 ENSG00000089163 ENSG00000288325 PMC5091819__F1 Fronto-striatal circuits originate in the frontal cortex and pass through the basal ganglia, which project via the thalamus back to frontal brain areas ENSG00000123360 ENSG00000145321 PMC5524517__F1 Integrated expression analysis identifies transcription networks in mouse and human gastric neoplasia ENSG00000119888 ENSG00000181104 ENSG00000072274 ENSG00000113140 ENSG00000168036 ENSG00000185885 ENSG00000288292 ENSG00000168610 ENSG00000137807 ENSG00000133048 ENSG00000011422 ENSG00000172216 ENSG00000157227 ENSG00000038427 ENSG00000136997 ENSG00000155660 ENSG00000291748 ENSG00000165376 ENSG00000100985 ENSG00000108821 ENSG00000162692 PMC3146054__F2 Regulation of microsomal triglyceride transfer protein ENSG00000171105 ENSG00000138823 ENSG00000005882 PMC9705465__F3 Hydrogen sulfide as a therapeutic option for the treatment of Duchenne muscular dystrophy and other muscle-related diseases ENSG00000139531 PMC4259167__F1 Anti-tumor functions of GD T cells ENSG00000231179 ENSG00000112149 ENSG00000204520 ENSG00000026103 PMC3039688__F7 Mapping Protein Interactions between Dengue Virus and Its Human and Insect Hosts ENSG00000171855 ENSG00000120833 ENSG00000159128 ENSG00000213928 ENSG00000081237 ENSG00000170677 ENSG00000027697 ENSG00000168610 ENSG00000142166 ENSG00000111537 ENSG00000105397 ENSG00000171150 ENSG00000115415 PMC7002987__F1 Different signaling pathways regulating melanogenesis ENSG00000019991 PMC5483589__F5 Ror2-expression-responsive module ENSG00000004975 ENSG00000162889 ENSG00000140564 ENSG00000135218 ENSG00000169071 ENSG00000101160 ENSG00000007866 ENSG00000114738 ENSG00000167580 ENSG00000164758 ENSG00000172216 ENSG00000196549 ENSG00000067606 ENSG00000057593 ENSG00000132326 ENSG00000182220 ENSG00000066136 ENSG00000163017 ENSG00000101333 PMC7402354__F2 Platelet signaling pathways that trigger ROS production ENSG00000135218 ENSG00000291971 ENSG00000076604 PMC3829165__F9 Schematic illustrating the signaling pathways for TGFB1-induced down-regulation of VE-cadherin and the inhibition of cell invasion in human trophoblast cells PMC9231053__F6A Estimation of Carbon Metabolism in Saccharomyces cerevisiae Acclimatized to Glycerol Assimilation with Quantitative PCR ENSG00000047597 PMC7002987__F3 Cytokines that inhibit or stimulate melanogenesis ENSG00000137033 ENSG00000125538 PMC2794709__F2 O-GlcNAc and phosphate regulate the insulin signaling pathway at the plasma membrane ENSG00000147162 ENSG00000169047 PMC9340222__F2 Traditional Chinese Medicine in the Treatment of Chronic Kidney Diseases: Theories, Applications, and Mechanisms ENSG00000162711 ENSG00000198793 ENSG00000168036 PMC9464648__F2 From cerebral ischemia towards myocardial, renal, and hepatic ischemia: Exosomal miRNAs as a general concept of intercellular communication in ischemia-reperfusion injury ENSG00000122566 ENSG00000128191 ENSG00000113360 ENSG00000123908 PMC5271383__F2 Regulatory mechanisms of NLRP3 inflammasome assembly ENSG00000162711 ENSG00000185515 PMC11689543__F5 Inflammatory and immunoregulatory role of megakaryocytes in sepsis ENSG00000278718 ENSG00000162711 ENSG00000143878 ENSG00000137033 ENSG00000145777 ENSG00000121966 ENSG00000111537 ENSG00000164430 ENSG00000163914 ENSG00000189403 ENSG00000136869 ENSG00000126353 ENSG00000142089 PMC9686310__F6 A muscle cell and the proteins linked to protein turnover and quality control ENSG00000105993 ENSG00000119401 ENSG00000005893 ENSG00000284099 ENSG00000151929 ENSG00000160131 PMC11689543__F3 Enhanced thrombopoiesis in sepsis ENSG00000167772 ENSG00000168610 PMC10143456__F7 Dickkopf-1 Acts as a Profibrotic Mediator in Progressive Chronic Kidney Disease ENSG00000281324 ENSG00000162337 PMC12170861__F4 Distribution of common targets in the main signaling pathways ENSG00000124102 ENSG00000100422 ENSG00000041982 ENSG00000130528 ENSG00000156026 ENSG00000186716 PMC5590044__F6 Schematic of anti-EMT pathway of Rb1 ENSG00000139687 PMC9254539__F2 Lipid metabolism in tumor microenvironment: novel therapeutic targets ENSG00000110921 ENSG00000113161 ENSG00000104549 ENSG00000167508 PMC6997842__F1 Brain-derived neurotrophic factor (BDNF) mediation in the anti-inflammatory and neuroprotective response of Alpha-melanocyte-stimulating hormone/melanocortin 4 receptor Alpha-MSH/MC4R against damage produced by excessive alcohol consumption ENSG00000002330 ENSG00000125538 PMC11387119__F3 Inflammasome sensors have diverse roles in tumorigenesis ENSG00000162711 ENSG00000163568 ENSG00000174885 ENSG00000091106 ENSG00000168610 ENSG00000293532 PMC6988351__F8 Inflammasome pathway ENSG00000125538 ENSG00000132693 PMC9301571__F2 Application of Small Molecules in the Central Nervous System Direct Neuronal Reprogramming ENSG00000198793 ENSG00000164690 ENSG00000281857 PMC4215754__F3 KEGG B cell signaling pathway tuned in CD19 B cells and CD4 T cells ENSG00000105369 ENSG00000109320 ENSG00000134215 ENSG00000115904 ENSG00000213341 ENSG00000117322 ENSG00000010671 ENSG00000177455 ENSG00000095585 ENSG00000117020 ENSG00000166501 ENSG00000197943 ENSG00000198286 PMC4215754__F2 Visualization of KEGG B Cell Receptor Signaling Pathway after parsing and automatic correction ENSG00000104365 ENSG00000285321 ENSG00000100906 ENSG00000109320 ENSG00000134215 ENSG00000110651 ENSG00000213341 ENSG00000117322 ENSG00000010671 ENSG00000177455 ENSG00000095585 ENSG00000117020 ENSG00000198286 PMC8670018__F1 T cell-associated tissues and T cell activation by RANKL-RANK-OPG ENSG00000226275 ENSG00000160224 ENSG00000111321 ENSG00000175104 PMC3584666__F1 Toll-like receptor (TLR) signaling pathway ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC4215754__F4 KEGG B cell signaling pathway after tissue specific and PPI-based tuning in CD19 B cells ENSG00000095585 ENSG00000104365 ENSG00000282905 ENSG00000100906 ENSG00000109320 ENSG00000115904 ENSG00000213341 ENSG00000121879 ENSG00000160293 ENSG00000100485 ENSG00000105669 ENSG00000198286 PMC8474727__F6 ALDOA inhibits cell cycle arrest induced by DNA damage via the ATM-PLK1 pathway in pancreatic cancer cells ENSG00000149311 ENSG00000166851 PMC9339679__F3 Ubiquitin specific proteases in the immune microenvironment of prostate cancer: A new direction ENSG00000124422 ENSG00000026508 ENSG00000168036 ENSG00000136014 PMC3366009__F8 T cell signaling pathway used by A2 and A9 ENSG00000291603 ENSG00000111537 ENSG00000107485 PMC11995686__F3 NFZ signaling pathway diagram ENSG00000157554 ENSG00000171791 ENSG00000143258 ENSG00000168610 PMC4622601__F1 Mechanism that result in aberrant Wnt/Beta-catenin signaling in colon cancer ENSG00000134982 ENSG00000168036 ENSG00000104332 PMC2943975__F1 TOR signaling never gets old: Aging, longevity and TORC1 activity ENSG00000134086 ENSG00000266173 ENSG00000198793 ENSG00000284161 ENSG00000167658 ENSG00000167965 PMC8301407__F3 Immune Influencers in Action: Metabolites and Enzymes of the Tryptophan-Kynurenine Metabolic Pathway ENSG00000188676 PMC5928365__F7 Ror2‐dependent noncanonical Wnt signaling ENSG00000281324 ENSG00000169071 ENSG00000181788 ENSG00000162337 ENSG00000168036 PMC3287362__F1 The anatomic and molecular mechanisms of sepsis-mediated sympathoexcitation and ghrelin's anti-inflammatory effect via sympathoinhibition ENSG00000198576 ENSG00000136869 PMC8408949__F1 Biology of bone morphogenetic protein signaling pathway in cerebrovascular system ENSG00000170365 PMC4822108__F3 Analysis of TRRAP as a Potential Molecular Marker and Therapeutic Target for Breast Cancer ENSG00000012048 ENSG00000124422 ENSG00000166337 ENSG00000120533 ENSG00000136997 ENSG00000168036 ENSG00000205250 ENSG00000136518 ENSG00000114166 ENSG00000196367 PMC5674948__F5 Summary of age, BMI, and differential correlation results (a) BMI and age independently increase inflammation in adjacent normal tissue (arrow) ENSG00000140285 ENSG00000107485 ENSG00000078098 PMC5934344__F1 Cellular and Molecular Mechanisms Underlying Planar Cell Polarity Pathway Contributions to Cancer Malignancy ENSG00000100592 ENSG00000134982 ENSG00000168036 ENSG00000067900 PMC3039927__F1 Organellar Ca2+ buffering and intracellular Ca2+ dynamics ENSG00000130528 ENSG00000167323 ENSG00000293604 ENSG00000167434 PMC8998661__F2 Autotaxin/Lysophosphatidic Acid Axis: From Bone Biology to Bone Disorders ENSG00000178860 ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000152592 ENSG00000198670 ENSG00000067900 PMC5934344__F3 Cellular and Molecular Mechanisms Underlying Planar Cell Polarity Pathway Contributions to Cancer Malignancy ENSG00000100592 ENSG00000198929 ENSG00000067900 PMC5934344__F2 Cellular and Molecular Mechanisms Underlying Planar Cell Polarity Pathway Contributions to Cancer Malignancy ENSG00000100592 PMC3874981__F5 NELL-1 signaling pathway ENSG00000138795 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000128602 PMC3874981__F4 Schematic of Hedgehog signaling pathway ENSG00000106571 ENSG00000128602 PMC5297831__F2 The mTOR signaling pathway ENSG00000155792 PMC4614341__F1 Schematic of signaling pathways involving the DNA damage response (DDR) pathway in apical and basal cells in the developing neuroepithelium ENSG00000149311 ENSG00000175054 PMC7249467__F5 Alterations in Plasma microRNA and Protein Levels in War Veterans with Chronic Mild Traumatic Brain Injury ENSG00000002330 PMC7046546__F3 Signaling due to A ENSG00000111537 ENSG00000248329 ENSG00000135517 PMC8607366__F3 Targeting cardiomyocyte proliferation as a key approach of promoting heart repair after injury ENSG00000156076 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000185269 PMC4657327__F2 FA/BRCA pathway and crosstalk between FA and other DNA repair pathways ENSG00000149311 ENSG00000175054 ENSG00000175643 ENSG00000178966 PMC8607366__F2 Targeting cardiomyocyte proliferation as a key approach of promoting heart repair after injury ENSG00000150457 ENSG00000131023 PMC3874981__F3 Beta-catenin dependent and independent Wnt signaling pathways ENSG00000138795 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC4391727__F5 Differentially expressed genes related to BMP signalling at day 0 to 3 of arthritis in comparison to non-induced controls ENSG00000152785 ENSG00000134363 ENSG00000213853 ENSG00000204217 PMC7263055__F2 Establishment of type 2 inflammation in ECRS ENSG00000133710 ENSG00000137033 ENSG00000145777 ENSG00000166090 PMC7335243__F3 Possible viral entry and replication mechanism of SARS-CoV-2 ENSG00000130234 PMC9231053__F5A Estimation of Carbon Metabolism in Saccharomyces cerevisiae Acclimatized to Glycerol Assimilation with Quantitative PCR ENSG00000167701 PMC8435728__F4 RNA Sequencing for Personalized Treatment of Metastatic Leiomyosarcoma: Case Report ENSG00000004975 ENSG00000132906 ENSG00000157404 ENSG00000002330 ENSG00000157764 ENSG00000100906 ENSG00000198793 ENSG00000142273 ENSG00000171791 ENSG00000099942 ENSG00000100485 ENSG00000197461 ENSG00000145604 ENSG00000122025 ENSG00000117020 ENSG00000049130 ENSG00000136997 ENSG00000146648 PMC3827358__F8 Lipopolysaccharide Induces Degradation of Connexin43 in Rat Astrocytes via the Ubiquitin-Proteasome Proteolytic Pathway ENSG00000182533 ENSG00000069869 ENSG00000136869 PMC7567113__F8 BNip1-mediated apoptosis in photoreceptors ENSG00000053501 ENSG00000265808 ENSG00000101350 ENSG00000168818 ENSG00000171791 ENSG00000113734 PMC4404867__F1 Coagulation, anticoagulation and fibrinolysis maintain a delicate physiological balance between bleeding and thrombosis ENSG00000003436 ENSG00000122194 PMC3767435__F2 Interactions between TLR7 and TLR9 agonists and receptors regulate innate immune responses by astrocytes and microglia ENSG00000112799 ENSG00000243414 ENSG00000008438 ENSG00000171855 ENSG00000282905 ENSG00000102871 ENSG00000150455 ENSG00000173702 ENSG00000010671 ENSG00000138834 ENSG00000170322 ENSG00000189403 ENSG00000164400 ENSG00000064012 ENSG00000115594 ENSG00000104365 ENSG00000154589 ENSG00000100906 ENSG00000109320 ENSG00000108342 ENSG00000173039 ENSG00000065559 ENSG00000213341 ENSG00000168040 ENSG00000127666 ENSG00000006062 ENSG00000276561 ENSG00000169245 ENSG00000226275 ENSG00000108691 ENSG00000111537 ENSG00000244687 ENSG00000170458 ENSG00000118503 ENSG00000177606 ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000204498 ENSG00000184216 PMC9031072__F2 Erythropoietin as a Neuroprotective Drug for Newborn Infants: Ten Years after the First Use ENSG00000187266 PMC2838200__F3 Proposed scheme for how macrophage-based nanoparticle drug delivery could affect disease outcomes in neurodegenerative disorders PMC4452916__F3 The effects of hrHPV on NFKB signaling ENSG00000104856 ENSG00000174125 ENSG00000137275 ENSG00000102871 ENSG00000173039 ENSG00000168040 ENSG00000127191 ENSG00000239732 ENSG00000171720 ENSG00000088888 ENSG00000187554 ENSG00000082512 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000146648 ENSG00000164342 PMC9214686__F2 Signalling pathways downstream of cGAS and of endosomal TLRs ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC4762514__F4 Metabolic pathway alterations in PCT ENSG00000157426 ENSG00000100522 ENSG00000164904 ENSG00000147162 ENSG00000105835 ENSG00000291814 ENSG00000124357 ENSG00000185973 ENSG00000159399 ENSG00000016391 ENSG00000013375 ENSG00000116984 PMC6011013__F5 Integration of mRNA data and CNAs profiles: BMD+DAD-screening network using Coxnet (top) and ADMMnet (bottom) methods with mRNA expression data and the integration of mRNA data and CNAs profiles ENSG00000160867 ENSG00000197532 ENSG00000147896 ENSG00000120235 ENSG00000284723 ENSG00000172640 PMC6011013__F4 mRNA expression data: BMD+DAD-screening network using Coxnet (left) and ADMMnet (right) methods with mRNA expression data and the integration of mRNA data and CNAs profiles ENSG00000160867 ENSG00000118680 ENSG00000171848 ENSG00000115353 ENSG00000132746 ENSG00000171791 PMC3558460__F1 Signal activation of human somatostatin receptor subtype-2 by membrane-displayed somatostatin ENSG00000180616 PMC4856717__F1 Main pathways involved in CD40-TRAF signaling ENSG00000108691 PMC3009535__F3 Functional module of the CXC chemokine pathway uniquely identified by NeMo ENSG00000184381 ENSG00000120063 ENSG00000117215 ENSG00000158786 ENSG00000188257 ENSG00000276870 ENSG00000188784 ENSG00000100078 ENSG00000088256 ENSG00000127472 PMC8124173__F3 Molecular Targets of Manganese-Induced Neurotoxicity: A Five-Year Update ENSG00000116688 ENSG00000120868 ENSG00000171791 PMC6462412__F2 DNA repair pathways—a toolkit for viral replication ENSG00000012048 ENSG00000175054 ENSG00000083093 ENSG00000138346 ENSG00000178295 ENSG00000154920 ENSG00000144554 ENSG00000188827 ENSG00000197299 ENSG00000051180 ENSG00000139618 PMC2660752__F6 Metabolic origin of glyoxylate in M ENSG00000166278 PMC5440111__F2 Enhanced anabolic PI3K/Akt pathway in a cancer cell ENSG00000131473 ENSG00000002330 ENSG00000198793 ENSG00000136997 PMC4912847__F1 Exosomes in liver pathology ENSG00000085117 ENSG00000110651 ENSG00000135404 ENSG00000113360 PMC3294420__F3 Integrating Mechanisms for Insulin Resistance: Common Threads and Missing Links ENSG00000135218 ENSG00000100344 ENSG00000150907 ENSG00000169047 ENSG00000136869 ENSG00000198670 ENSG00000100219 ENSG00000168610 ENSG00000123689 ENSG00000062282 ENSG00000062485 PMC3294420__F2 Integrating Mechanisms for Insulin Resistance: Common Threads and Missing Links ENSG00000135218 ENSG00000169047 ENSG00000136869 ENSG00000198670 ENSG00000062485 PMC8301965__F9 Hair Growth Stimulation Effect of Centipeda minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11937447__F2 Functions and mechanisms of lncRNAs in endoderm differentiation ENSG00000164736 ENSG00000133937 ENSG00000163251 ENSG00000141448 ENSG00000105991 ENSG00000163064 ENSG00000073792 ENSG00000164778 ENSG00000102974 PMC10865172__F3 Roles and mechanisms of ESM1 in tumor angiogenesis ENSG00000164283 ENSG00000128917 ENSG00000110799 ENSG00000138798 ENSG00000198793 ENSG00000157625 ENSG00000168610 ENSG00000146648 PMC4467862__F3 Crosstalk between erythropoiesis and iron metabolism involving TGFB family member GDF11 ENSG00000178752 ENSG00000135414 PMC4247524__F2 Long-patch BER pathway ENSG00000105486 ENSG00000132646 PMC4711368__F4 Signaling pathways of cytokines in GnRH neurons ENSG00000242689 ENSG00000125538 ENSG00000128342 PMC4247524__F1 Short-patch BER pathway ENSG00000039650 PMC9214686__F4 Transport and metabolism of cGAMP ENSG00000164430 ENSG00000170458 ENSG00000197594 ENSG00000119457 PMC3737373__F9 RNAi Mediated Tiam1 Gene Knockdown Inhibits Invasion of Retinoblastoma ENSG00000156299 ENSG00000138798 ENSG00000026508 PMC3258560__F1 Signal transduction by TGFB family members ENSG00000170365 ENSG00000137834 ENSG00000163914 PMC8246814__F2 Endothelial cell and T‐cell crosstalk: Targeting metabolism as a therapeutic approach in chronic inflammation ENSG00000135218 ENSG00000079432 PMC11121563__F1 Non-Coding RNA as Biomarkers and Their Role in the Pathogenesis of Gastric Cancer—A Narrative Review ENSG00000102962 ENSG00000275385 ENSG00000198793 ENSG00000061273 ENSG00000103888 ENSG00000083799 ENSG00000108821 ENSG00000155629 PMC3303613__F1 Signaling pathways in the pathogenesis of nasopharyngeal carcinoma (NPC) ENSG00000134982 ENSG00000135446 ENSG00000136997 ENSG00000164362 ENSG00000168036 ENSG00000146648 PMC9554952__F4 Review of Herbal Medicine-Based Phytochemical of Garcinia as Molecular Therapy for Breast Cancer ENSG00000168610 ENSG00000146648 PMC11121563__F3 Non-Coding RNA as Biomarkers and Their Role in the Pathogenesis of Gastric Cancer—A Narrative Review ENSG00000198793 PMC5776718__F1 Overview of the L-lysine biosynthetic pathway in Synechococcus sp ENSG00000122966 ENSG00000172005 PMC9554952__F3 Review of Herbal Medicine-Based Phytochemical of Garcinia as Molecular Therapy for Breast Cancer ENSG00000102871 ENSG00000168040 ENSG00000026103 PMC11121563__F2 Non-Coding RNA as Biomarkers and Their Role in the Pathogenesis of Gastric Cancer—A Narrative Review ENSG00000134531 PMC3159580__F3 Not(ch) just development: Notch signalling in the adult brain ENSG00000117525 ENSG00000187957 ENSG00000168214 ENSG00000198793 ENSG00000172889 ENSG00000168036 ENSG00000123374 ENSG00000164690 ENSG00000133961 ENSG00000168610 PMC1884140__F11 Schematic representation of the differentially expressed genes and how they are induced upon injection by (A) pristane or (B) phytol ENSG00000262406 ENSG00000111537 ENSG00000089127 ENSG00000183486 ENSG00000135114 ENSG00000276561 PMC11121563__F4 Non-Coding RNA as Biomarkers and Their Role in the Pathogenesis of Gastric Cancer—A Narrative Review PMC5723907__F1 General induction and receptor signaling pathways of type I and type III IFNs ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000125347 ENSG00000276561 ENSG00000142166 PMC4141691__F5 Genome-Wide Analysis of miRNA Signature in the APPswe/PS1ΔE9 Mouse Model of Alzheimer's Disease ENSG00000175634 ENSG00000112964 ENSG00000198793 ENSG00000164327 PMC5376156__F1 Nanosecond Pulsed Electric Fields (nsPEFs) Regulate Phenotypes of Chondrocytes through Wnt/Beta-catenin Signaling Pathway ENSG00000125398 ENSG00000168036 PMC6136541__F4 E2 on bovine mammary epithelial cells during Staphylococcus aureus infection ENSG00000125538 ENSG00000143556 PMC3775402__F1 Alternative splicing regulation of the Ras-MAPK pathway PMC5397778__F3 Helicobacter pylori-induced chronic inflammatory and neoplastic diseases ENSG00000178860 ENSG00000165556 ENSG00000111537 ENSG00000164690 PMC5397778__F2 Simplified schematic depiction of the canonical hedgehog (HH) signal transduction pathway within the primary cilium ENSG00000143147 ENSG00000180447 ENSG00000106571 ENSG00000164161 ENSG00000144857 ENSG00000128602 PMC7154114__F5 Systems biology is an interdisciplinary field that involves computational and mathematical investigations for modeling a complex biological mechanism ENSG00000134086 ENSG00000129757 ENSG00000075218 ENSG00000166851 ENSG00000146648 ENSG00000251493 PMC3775402__F2 Alternative splicing regulation of the PI3K-mTOR pathway ENSG00000198793 PMC3759017__F1 Key mutational and therapeutic targets in melanoma ENSG00000157404 ENSG00000117020 ENSG00000065833 ENSG00000157764 PMC4918247__F1 HGF/c-Met signaling cascades.Notes: Upon binding of HGF to its receptor c-Met, c-Met is dimerized and activated by phosphorylation of Tyr 1234 and Tyr 1235 residues ENSG00000019991 ENSG00000070831 ENSG00000198793 ENSG00000168610 PMC6163197__F2 Main metabolic pathways triggered by chronic brain hypoperfusion (CBH) ENSG00000149311 ENSG00000042832 ENSG00000198793 ENSG00000171791 PMC7880438__F8 PB1 protein of influenza A virus inhibits the innate immune response by targeting MAVS for NBR1-mediated selective autophagic degradation ENSG00000183735 ENSG00000188554 ENSG00000088888 PMC6936254__F2 PPI network of DEGs ENSG00000101670 ENSG00000138722 ENSG00000159784 ENSG00000162496 ENSG00000110492 ENSG00000133574 ENSG00000101280 ENSG00000105499 ENSG00000124212 ENSG00000171388 ENSG00000174564 ENSG00000070669 ENSG00000140323 ENSG00000170365 ENSG00000132464 ENSG00000155016 ENSG00000128052 ENSG00000277263 ENSG00000164400 ENSG00000164440 ENSG00000171560 ENSG00000137267 ENSG00000101210 ENSG00000003436 ENSG00000196358 ENSG00000189056 ENSG00000086991 ENSG00000076706 ENSG00000116701 ENSG00000166670 ENSG00000184916 ENSG00000073605 ENSG00000171303 ENSG00000292214 ENSG00000185664 ENSG00000188611 ENSG00000174059 ENSG00000204936 ENSG00000128965 PMC9653480__F6 Obesity downregulates lipid metabolism genes in first trimester placenta ENSG00000042832 ENSG00000161533 PMC6198802__F3 Key cellular and molecular pathways regulating blood-brain barrier integrity ENSG00000164690 ENSG00000112715 ENSG00000154188 ENSG00000133216 PMC6707807__F1 Enriched immunological pathway and genes ENSG00000066468 ENSG00000013016 ENSG00000291603 ENSG00000157985 ENSG00000148082 ENSG00000010810 ENSG00000011028 ENSG00000106299 ENSG00000276051 ENSG00000096264 PMC8326125__F8 TNFA augments CXCL10/CXCR3 axis activity to induce Epithelial-Mesenchymal Transition in colon cancer cell ENSG00000169245 ENSG00000186810 PMC8201612__F4 Amino Acid Trafficking and Skeletal Muscle Protein Synthesis: A Case of Supply and Demand ENSG00000198793 ENSG00000167965 ENSG00000163644 PMC6027909__F1 Primary mechanisms by which AIBP protects against macrophage inflammatory response ENSG00000125538 ENSG00000172936 ENSG00000168610 PMC8201612__F3 Amino Acid Trafficking and Skeletal Muscle Protein Synthesis: A Case of Supply and Demand ENSG00000180210 ENSG00000198793 ENSG00000155792 PMC8201612__F2 Amino Acid Trafficking and Skeletal Muscle Protein Synthesis: A Case of Supply and Demand ENSG00000169047 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC2394714__F10 TGFB1-induced PAI-1 expression in VSMC ENSG00000146648 PMC5487013__F7 Data analysis framework for biomedical big data: Application on mesoderm differentiation of human pluripotent stem cells ENSG00000281324 ENSG00000162337 ENSG00000095739 ENSG00000147869 ENSG00000167941 ENSG00000185269 PMC6611711__F1 Lipid biosynthesis in cancer cells ENSG00000131473 ENSG00000042832 ENSG00000198793 ENSG00000099194 ENSG00000026103 PMC3978476__F4 Major metabolites and genes contributing to the choline metabolism pathway ENSG00000184381 ENSG00000110721 ENSG00000032444 ENSG00000100288 ENSG00000112499 ENSG00000276870 ENSG00000188784 ENSG00000158555 ENSG00000130653 ENSG00000105223 ENSG00000161714 PMC5352242__F1 Schematic illustration of the intracellular trafficking dynamics of mitochondria-targeting nanoparticles ENSG00000158828 ENSG00000214253 PMC3560328__F2 DNA interstrand crosslink repair and cancer ENSG00000181544 ENSG00000187790 ENSG00000115392 ENSG00000187741 ENSG00000112039 ENSG00000158169 ENSG00000139618 ENSG00000012048 ENSG00000175054 ENSG00000144554 ENSG00000175643 ENSG00000197299 ENSG00000178966 ENSG00000276787 PMC9555684__F1 Metabolic recycling of storage lipids promotes squalene biosynthesis in yeast ENSG00000157554 ENSG00000197429 PMC3560328__F4 DNA interstrand crosslink repair and cancer ENSG00000154920 ENSG00000276787 PMC9629834__SF4_2 Protein network and Netrin-DCC pathway analysis ENSG00000099204 ENSG00000070831 ENSG00000291971 ENSG00000136854 ENSG00000138395 ENSG00000161203 ENSG00000008086 ENSG00000065320 ENSG00000042753 ENSG00000132639 ENSG00000179295 ENSG00000196961 ENSG00000148660 ENSG00000156298 ENSG00000197283 ENSG00000166501 ENSG00000183020 ENSG00000157103 ENSG00000124181 ENSG00000185129 ENSG00000145349 PMC3560328__F3 DNA interstrand crosslink repair and cancer ENSG00000012061 ENSG00000012048 ENSG00000154920 ENSG00000144554 ENSG00000187790 ENSG00000108384 ENSG00000197299 ENSG00000051180 ENSG00000276787 ENSG00000139618 PMC5293538__F1 Abbreviated polyamine synthesis pathway ENSG00000116771 ENSG00000116649 ENSG00000102172 PMC2630373__F1 Regulation of G1/S transition by growth factor (insulin and IGF-I) signaling in Beta-cells ENSG00000169047 ENSG00000139515 ENSG00000118971 PMC4380073__F2 Simplistic overview of the top two mutation-enriched transduction signaling pathways in ATC as according to the Genomatix Pathway System ENSG00000186575 ENSG00000157764 ENSG00000198793 ENSG00000121879 ENSG00000140443 PMC8460515__F2 Pharmacological properties of baicalin on liver diseases: a narrative review ENSG00000162711 ENSG00000164483 ENSG00000096717 ENSG00000023909 ENSG00000026103 PMC8615556__F1 miRNA as a Modulator of Immunotherapy and Immune Response in Melanoma ENSG00000124422 ENSG00000159128 ENSG00000115415 ENSG00000168036 ENSG00000027697 ENSG00000273686 ENSG00000162772 ENSG00000277943 ENSG00000140443 PMC7706582__F4 Epigenetic Mechanisms in Leukemias and Lymphomas ENSG00000112576 ENSG00000110330 ENSG00000125735 ENSG00000127528 ENSG00000171791 ENSG00000179295 ENSG00000122025 ENSG00000178573 ENSG00000136997 ENSG00000137265 ENSG00000118515 ENSG00000213999 ENSG00000283060 ENSG00000139687 ENSG00000198286 ENSG00000026103 ENSG00000105369 ENSG00000005339 ENSG00000157764 ENSG00000173575 ENSG00000100906 ENSG00000148400 ENSG00000007312 ENSG00000273686 ENSG00000166278 ENSG00000127191 ENSG00000168610 ENSG00000177565 ENSG00000149311 ENSG00000120063 ENSG00000115524 ENSG00000118503 ENSG00000186716 ENSG00000196092 ENSG00000172936 ENSG00000055609 ENSG00000131323 ENSG00000112149 ENSG00000127616 PMC7730528__F10 Graphical illustration of prolidase-dependent EGFR, B1-integrin receptor, TGFB1, and IGF-1R-downstream signaling ENSG00000169291 ENSG00000291971 ENSG00000167941 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC7412373__F4 Multiple Roles of Hepatitis B Virus X Protein (HBx) Dysregulated MicroRNA in Hepatitis B Virus-Associated Hepatocellular Carcinoma (HBV-HCC) and Immune Pathways ENSG00000198793 ENSG00000168036 ENSG00000172936 PMC7412373__F3 Multiple Roles of Hepatitis B Virus X Protein (HBx) Dysregulated MicroRNA in Hepatitis B Virus-Associated Hepatocellular Carcinoma (HBV-HCC) and Immune Pathways ENSG00000087095 ENSG00000138166 ENSG00000198793 ENSG00000133740 ENSG00000057663 ENSG00000026103 PMC4352617__F3 Proposed mechanism for transcription-dependent p73-induced apoptosis ENSG00000168040 ENSG00000075240 ENSG00000164305 PMC6611711__F6 Phospholipid and TG synthesis pathway ENSG00000042832 ENSG00000173599 ENSG00000169710 ENSG00000198670 ENSG00000184207 ENSG00000102172 ENSG00000133027 PMC11013731__F6 Sea Cucumber and Blueberry Extracts Suppress Inflammation and Reduce Acute Lung Injury through the Regulation of NFKB/MAPK/JNK Signaling Pathway in Lipopolysaccharide-Treated C57BL/6 Mice ENSG00000132478 ENSG00000136869 PMC5487013__F8 Data analysis framework for biomedical big data: Application on mesoderm differentiation of human pluripotent stem cells ENSG00000138795 ENSG00000156076 ENSG00000174804 ENSG00000277641 ENSG00000164736 ENSG00000163251 ENSG00000147869 ENSG00000175832 ENSG00000136997 ENSG00000137203 ENSG00000104371 ENSG00000019549 ENSG00000107485 ENSG00000076716 ENSG00000145349 ENSG00000168772 PMC7412373__F1 Multiple Roles of Hepatitis B Virus X Protein (HBx) Dysregulated MicroRNA in Hepatitis B Virus-Associated Hepatocellular Carcinoma (HBV-HCC) and Immune Pathways ENSG00000178573 ENSG00000134982 ENSG00000168036 ENSG00000136869 ENSG00000110693 PMC7254050__F5 Proteins co-associated with hyaluronidase (HYAL)-2 have roles in actin organization and contraction function ENSG00000068001 ENSG00000291420 ENSG00000123165 ENSG00000196604 PMC5573869__F3 Regulation of the G1/S cell cycle checkpoint pathway by Pontin/Reptin at multiple levels ENSG00000122882 ENSG00000135446 ENSG00000136997 ENSG00000168036 ENSG00000123374 ENSG00000105810 PMC7461995__F1 Pseudomonas aeruginosa Can Degrade Interferon λ, Thereby Repressing the Antiviral Response of Bronchial Epithelial Cells ENSG00000213928 ENSG00000105397 ENSG00000089127 ENSG00000157601 ENSG00000125347 ENSG00000276561 PMC7465013__F5 Gene networks analysis of quercetin–resveratrol modulated genes suggest IGF1 and BCL2 as key signaling nodes associated with anti-PCa effects ENSG00000110711 ENSG00000184012 ENSG00000163453 ENSG00000163132 PMC5573869__F6 Regulation of DNA damage response and repair by Pontin/Reptin ENSG00000100811 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000144554 ENSG00000128908 PMC5573869__F5 Regulation of transcription factors by Pontin/Reptin ENSG00000005175 ENSG00000157557 ENSG00000157500 ENSG00000125538 ENSG00000136997 ENSG00000164362 ENSG00000168036 ENSG00000136044 ENSG00000169567 PMC8509131__F1 NLRP3 Inflammasome: Relevance in Solid Organ Transplantation ENSG00000162711 ENSG00000189403 ENSG00000265972 ENSG00000168040 PMC5573869__F7 Role of Pontin/Reptin in the EMT pathway ENSG00000169554 ENSG00000138798 ENSG00000170558 ENSG00000198793 ENSG00000168036 ENSG00000168610 ENSG00000146648 PMC6299112__F4 Proposed roles for miR-137 at the glutamatergic synapse ENSG00000168993 ENSG00000198793 ENSG00000164327 ENSG00000101752 ENSG00000067715 PMC6299112__F3 Neuronal signaling events that influence miRNA biogenesis, activity, and degradation ENSG00000113360 ENSG00000123908 ENSG00000155363 PMC6299112__F2 Overview of the canonical miRNA pathway, from synthesis to degradation ENSG00000128191 ENSG00000113360 ENSG00000155363 PMC9134343__F3 Controversial Role of IL-33 in Lung Cancer ENSG00000137033 ENSG00000172936 ENSG00000049768 PMC11599537__F3 TLN1 in cancers ENSG00000180210 ENSG00000117525 ENSG00000137076 PMC8748693__F3 Metabolic routes contributing to ferroptosis ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000197429 ENSG00000164466 ENSG00000102967 ENSG00000115107 PMC10854112__F10 Schematic showing the preliminary mechanism of Gnao1 in SCs regulating SC differentiation and myelination ENSG00000184221 ENSG00000162409 ENSG00000122877 ENSG00000185668 ENSG00000184486 PMC8630058__F5 Metabolic pathway linking methane oxidation to selenate reduction by bacterial consortia ENSG00000108960 ENSG00000172482 ENSG00000062485 PMC6579773__F2 Alternative pathway of the complement system ENSG00000039537 PMC7284929__F7 Ingenuity Pathway Analysis (IPA) and western blotting validation of common differentially expressed proteins ENSG00000143158 ENSG00000135218 ENSG00000104760 ENSG00000115657 ENSG00000010256 ENSG00000076555 ENSG00000155906 ENSG00000079557 ENSG00000101365 ENSG00000112293 ENSG00000233954 ENSG00000288411 ENSG00000117054 ENSG00000073060 ENSG00000005421 ENSG00000151366 ENSG00000186010 ENSG00000168924 ENSG00000164708 ENSG00000130508 ENSG00000113790 ENSG00000105379 ENSG00000167434 PMC6923491__F2 Bayesian theorem-optimized possible optimal acting pathway of axonal regeneration ENSG00000104044 ENSG00000087842 PMC6923491__F1 Pathway diagram of axon regeneration regulatory network ENSG00000104044 PMC6185869__F1 Simplified PI3K Signaling Cascade and Known Clinical Disorders Caused by Genetic Pathway Activation ENSG00000117020 ENSG00000002330 PMC8036978__F1 Simplified extrinsic signaling pathway from TNF-R1, Fas, DR4, and DR5 ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC7730007__F8 Mapping the S1P-S1PR1signaling pathway in differentiated SGBS and 3T3-L1 adipocytes ENSG00000117020 ENSG00000063176 ENSG00000141639 ENSG00000166484 ENSG00000182621 ENSG00000137841 ENSG00000135587 PMC4342569__F8 The multi-targeted tyrosine kinase inhibitor vandetanib plays a bifunctional role in non-small cell lung cancer cells ENSG00000163914 ENSG00000132478 PMC4484476__F7 Inhibition of Beta-Catenin signaling suppresses pancreatic tumor growth by disrupting nuclear Beta-Catenin/TCF-1 complex: Critical role of STAT-3 ENSG00000134982 ENSG00000168036 ENSG00000168610 PMC2718747__F10 A model of EGF/EGFR-induced inhibition of a Luminal-A phenotype in MCF-7 cells ENSG00000138798 ENSG00000107485 ENSG00000146648 PMC7513516__F1 Domain structure and signaling pathway of STAT3 ENSG00000169245 ENSG00000087245 ENSG00000122691 ENSG00000291971 ENSG00000136997 ENSG00000168610 ENSG00000082212 PMC7713510__F6 SRC-1 and SRC-2 serve critical roles in developmental regulation of 11Beta-HSD1 expression by glucocorticoids and cytokines ENSG00000125538 ENSG00000145321 PMC138687__F1 The TGFB signaling pathway, showing the activation cascade and points of inhibition (??) ENSG00000137834 ENSG00000095739 ENSG00000138798 PMC149906__F5 A model to explain the effects of varying Fgf8 dosage on cell survival ENSG00000170370 ENSG00000164056 ENSG00000176165 PMC3899875__F4 MiR-148b in the mTOR signalling pathway ENSG00000157764 ENSG00000169047 ENSG00000198793 ENSG00000164327 PMC3899875__F5 MiR-15a in the AD pathway ENSG00000132906 ENSG00000291983 ENSG00000142192 ENSG00000002330 ENSG00000168040 ENSG00000119912 ENSG00000064012 ENSG00000164305 PMC9546099__F5 Absorption, metabolism and excretion of opicapone in human healthy volunteers ENSG00000166278 PMC8843878__F3 Chinese herbal decoction astragalus and angelica exerts its therapeutic effect on renal interstitial fibrosis through the inhibition of MAPK, PI3K-Akt and TNF signaling pathways ENSG00000050628 ENSG00000138798 ENSG00000173039 ENSG00000087085 ENSG00000007908 ENSG00000112715 ENSG00000106546 ENSG00000132170 ENSG00000082175 ENSG00000149968 ENSG00000141279 ENSG00000136997 ENSG00000108344 ENSG00000146648 ENSG00000127948 PMC3517193__F1 Graphic illustration of the perturbation of the insulin signal transduction pathways by cellular stressors ENSG00000002330 ENSG00000110395 ENSG00000102034 ENSG00000169047 ENSG00000198793 ENSG00000133124 PMC6386093__F5 Metabolic profiling of intracellular metabolites involved in branched-chain amino acid catabolism ENSG00000122971 PMC3821079__F1 Schematic representation and overview of PI3K/AKT/mTOR/PTEN signaling ENSG00000198793 ENSG00000168036 PMC8368180__F1 Inflammation and the TME in oesophageal carcinogenesis ENSG00000111537 ENSG00000125538 PMC11648920__F3 Schematic diagram represents the DEGs expression enriched in SA, JA and ET signalling pathway ENSG00000221818 PMC3821079__F3 Several inhibitors linked to the PI3K/AKT/mTOR/PTEN signaling pathway are shown ENSG00000198793 ENSG00000168036 PMC11648920__F5 Various signalling pathways and resistance mechanisms in wheat in response to Puccinia infection ENSG00000105722 ENSG00000110395 PMC9235346__F3 Integrating proteomic and clinical data to discriminate major psychiatric disorders: Applications for major depressive disorder, bipolar disorder, and schizophrenia ENSG00000003436 ENSG00000170775 ENSG00000163131 ENSG00000119655 ENSG00000165471 PMC4091179__F10 Identification of a novel MTOR activator and discovery of a competing endogenous RNA regulating autophagy in vascular endothelial cells ENSG00000116001 ENSG00000198793 PMC4428629__F1 Structure of an NDR/LATS Kinase–Mob Complex Reveals a Novel Kinase–Coactivator System and Substrate Docking Mechanism ENSG00000157404 ENSG00000130234 ENSG00000291442 PMC4465887__F1 Advances in recent patent and clinical trial drug development for Alzheimer’s disease ENSG00000142192 ENSG00000087085 PMC3773820__F8 Role of Nor-1 in incretin-induced insulin expression and secretion and hypothetical localization of the TCF7L2 and NR4A3 SNP effects ENSG00000119508 PMC7385902__F3 Correlation plots for genes (absolute Pearson correlation > 0.4) that contributed to the enrichment of MAPK38 pathway in ER negative tumor and phosphocholine synthesis in ER negative normal-adjacent samples ENSG00000162889 ENSG00000110721 ENSG00000132793 ENSG00000100288 ENSG00000081189 PMC6457711__F2 Regulatory mechanism of calcium on HIF1A induction ENSG00000144935 ENSG00000167323 ENSG00000156026 ENSG00000198793 ENSG00000137672 PMC11591698__F1 General Hippo signaling pathway ENSG00000126016 ENSG00000186575 ENSG00000163914 ENSG00000197905 ENSG00000026508 ENSG00000168036 ENSG00000198670 ENSG00000007866 ENSG00000150457 ENSG00000132849 ENSG00000131023 ENSG00000074219 PMC6773241__F8 Graphical abstract showing the main findings of this study ENSG00000205250 ENSG00000146648 PMC11591698__F2 IPA ingenuity pathway analysis: IPA is a software application used for the analysis and interpretation of YAP’s complex biological interactions in cancer development ENSG00000134376 PMC11591698__F4 Hippo pathway ENSG00000186575 PMC9181096__F11 Ginsenoside Rc Promotes Bone Formation in Ovariectomy-Induced Osteoporosis In Vivo and Osteogenic Differentiation In Vitro ENSG00000134982 ENSG00000168036 PMC9224458__F2 MicroRNAs in Signaling Pathways Associated with the Pathogenesis of Idiopathic Pulmonary Fibrosis: A Focus on Epithelial-Mesenchymal Transition ENSG00000134982 ENSG00000168036 PMC5661129__F2 Crosstalk between cancer and cancer stem cell-related pathways ENSG00000138798 ENSG00000187140 ENSG00000115718 ENSG00000146648 ENSG00000106078 PMC4914454__F5 “The Expanding GRK Interactome: Implications in Cardiovascular Disease and Potential for Therapeutic Development” ENSG00000164879 ENSG00000108840 PMC4717619__F1 Schematic of tumor cell interactions in the brain ENSG00000107562 ENSG00000148400 ENSG00000185483 ENSG00000184916 ENSG00000146648 ENSG00000121966 PMC11705629__F5 AMPK signaling pathway in macrophages and fibroblasts cross-talk ENSG00000108691 ENSG00000198793 ENSG00000184371 PMC5241746__F10 Working model ENSG00000148400 ENSG00000146648 ENSG00000178568 PMC6033069__F4 The anti-inflammatory effects of MPQP on the LPS-induced inflammatory pathway ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC8268872__F1 Roles of the IGF Axis in the Regulation of the Metabolism: Interaction and Difference between Insulin Receptor Signaling and IGF-I Receptor Signaling ENSG00000169047 ENSG00000198793 PMC6430496__F2 Underlying molecular mechanisms of ZFAS1 in multiple human cancers ENSG00000156103 ENSG00000157227 ENSG00000127528 ENSG00000276920 ENSG00000123908 PMC11350703__F18 PDK1-mediated TGFB/Smad signaling pathway by hypoxia in yellow cattle and yak PASMCs PMC8306115__F3 Ciliary Signalling and Mechanotransduction in the Pathophysiology of Craniosynostosis ENSG00000137601 ENSG00000187049 ENSG00000119650 ENSG00000093009 ENSG00000147316 ENSG00000118965 ENSG00000112210 ENSG00000106571 ENSG00000187535 ENSG00000128602 ENSG00000163501 ENSG00000166037 ENSG00000062485 PMC8908322__F1 What Does Androgen Receptor Signaling Pathway in Sertoli Cells During Normal Spermatogenesis Tell Us? ENSG00000146648 PMC10816037__F1 Different signaling pathways affected by the probiotic strains with anti-obesity or anti-diabetic properties in C ENSG00000161533 PMC7563518__F1 Metabolic pathways of l-tryptophan (a) and l-arginine (b) ENSG00000262635 ENSG00000102172 ENSG00000188676 ENSG00000007171 PMC6764206__F4 Biosynthetic pathway of plasmalogens and diacyl phospholipids ENSG00000185813 ENSG00000173599 ENSG00000184207 ENSG00000134255 ENSG00000182326 ENSG00000241878 ENSG00000101290 ENSG00000133027 PMC5439240__F2 Paracellular intestinal barrier in health and inflammation ENSG00000184113 ENSG00000165376 PMC6070911__F1 Biosynthetic pathway of ansamitocin P-3 ENSG00000069482 ENSG00000102977 PMC5963017__F8 Pridopidine enhances cAMP/PKA and TrkB pathway genes in the YAC128 striatum ENSG00000120436 ENSG00000253148 ENSG00000291483 PMC9306014__F1 CDK4 stabilization and canonical function in the cell cycle ENSG00000134086 ENSG00000105401 ENSG00000135446 ENSG00000136997 PMC11274597__F1 Outline of the HH signaling pathway [16] ENSG00000166813 ENSG00000128602 PMC4440459__F16 Summary of Ingenuity Pathway Analysis (IPA) ENSG00000064666 ENSG00000112977 ENSG00000204577 ENSG00000197635 ENSG00000115415 ENSG00000059573 ENSG00000163993 ENSG00000140416 ENSG00000136068 PMC8908322__F3 What Does Androgen Receptor Signaling Pathway in Sertoli Cells During Normal Spermatogenesis Tell Us? ENSG00000284774 ENSG00000138798 ENSG00000145321 ENSG00000073921 ENSG00000145782 ENSG00000179348 ENSG00000146648 ENSG00000064300 PMC8908322__F2 What Does Androgen Receptor Signaling Pathway in Sertoli Cells During Normal Spermatogenesis Tell Us? ENSG00000125398 ENSG00000146648 PMC3588201__F1 Gene regulatory networks for cDC and pDC development ENSG00000104856 ENSG00000123685 ENSG00000122025 ENSG00000162676 ENSG00000156127 ENSG00000137265 ENSG00000168610 PMC6306406__F1 Schematic elucidation of IL-33 ENSG00000137033 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC7419519__F3 KEGG pathway mapping of CHO global spectral library ENSG00000118007 ENSG00000008952 ENSG00000134982 ENSG00000205250 ENSG00000277273 ENSG00000091651 ENSG00000171791 ENSG00000166851 ENSG00000198168 ENSG00000135506 ENSG00000276876 ENSG00000093009 ENSG00000175054 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000105810 ENSG00000108055 ENSG00000117399 ENSG00000149311 ENSG00000291983 ENSG00000145604 ENSG00000094804 ENSG00000101972 ENSG00000128272 ENSG00000144895 ENSG00000100387 ENSG00000135446 ENSG00000132646 PMC10177097__F9 Effects induced by Exe plus CBD in MCF-7aro cells ENSG00000109321 ENSG00000160182 PMC6126011__F2 Leptin intracellular signaling pathway ENSG00000169047 ENSG00000115138 ENSG00000168610 PMC3442876__F2 Autophagy in immunity ENSG00000188554 ENSG00000136436 ENSG00000125538 ENSG00000284099 ENSG00000189403 ENSG00000237693 PMC4571863__F11 Model showing that KLF17 suppresses cancer metastasis via a p53-dependent pathway (a) and showing that a novel positive feedback loop exists between p53 and KLF17 (b) ENSG00000171872 PMC3234240__F2 Radiation–Induced Signaling Results in Mitochondrial Impairment in Mouse Heart at 4 Weeks after Exposure to X-Rays ENSG00000131730 ENSG00000142192 ENSG00000067992 ENSG00000005882 ENSG00000189043 ENSG00000122873 ENSG00000163017 ENSG00000197616 ENSG00000113525 PMC4001935__F7 FoxD3 regulates cranial neural crest EMT via downregulation of Tetraspanin18 independent of its functions during neural crest formation ENSG00000187140 ENSG00000157570 ENSG00000100146 PMC8375236__F3 ATM at the crossroads of reactive oxygen species and autophagy ENSG00000149311 ENSG00000198793 ENSG00000288217 PMC8375236__F2 ATM at the crossroads of reactive oxygen species and autophagy ENSG00000149311 ENSG00000288217 PMC5738336__F9 KEGG (Kanehisa & Goto, 2000) PI3K-Akt signaling pathway (map04151) is enriched for genes differentially expressed between lesion and healthy lung tissue in cattle challenged with BRDC pathogens ENSG00000177455 ENSG00000103479 ENSG00000065833 ENSG00000002330 ENSG00000186716 ENSG00000198793 PMC6312990__F4 Signalling pathways related to PRL-3/EGFR/c-myc genes in cancer cells ENSG00000291971 ENSG00000146648 PMC11674862__F4 ADAM17 activation triggers AREG-dependent pathways ENSG00000115415 ENSG00000109321 ENSG00000146648 PMC6209233__F8 Proteomic analysis of human prostate cancer PC-3M-1E8 cells and PC-3M-2B4 cells of same origin but with different metastatic potential ENSG00000111837 ENSG00000172005 PMC8181544__F2 Is the Endothelium the Missing Link in the Pathophysiology and Treatment of COVID-19 Complications? ENSG00000130234 PMC11674862__F2 Interactions of ADAM17 with IL-6, IL-1B, and IL-15 ENSG00000125538 PMC4703318__F1 Molecular Pathways: Turning Proteasomal Protein Degradation into a Unique Treatment Approach ENSG00000168036 ENSG00000109670 ENSG00000185104 PMC6209233__F9 Proteomic analysis of human prostate cancer PC-3M-1E8 cells and PC-3M-2B4 cells of same origin but with different metastatic potential ENSG00000150991 ENSG00000100979 ENSG00000165269 PMC8425587__F1 Sequestosome 1/p62: A multitasker in the regulation of malignant tumor aggression (Review) ENSG00000284774 ENSG00000168036 ENSG00000196628 PMC8425587__F4 Sequestosome 1/p62: A multitasker in the regulation of malignant tumor aggression (Review) ENSG00000284099 ENSG00000175104 ENSG00000136826 PMC8425587__F6 Sequestosome 1/p62: A multitasker in the regulation of malignant tumor aggression (Review) ENSG00000188554 ENSG00000134086 ENSG00000138798 ENSG00000175104 ENSG00000146648 PMC8425587__F5 Sequestosome 1/p62: A multitasker in the regulation of malignant tumor aggression (Review) ENSG00000198793 ENSG00000284099 ENSG00000130159 ENSG00000175104 ENSG00000079999 PMC9345804__F1 Molecular Alterations in Malignant Pleural Mesothelioma: A Hope for Effective Treatment by Targeting YAP ENSG00000110448 ENSG00000198793 ENSG00000026508 ENSG00000166169 ENSG00000146648 PMC3494151__F4 Impact of SIRT1 knockout on selected cellular pathways and protein complexes ENSG00000144028 ENSG00000143799 ENSG00000100410 ENSG00000168395 ENSG00000136937 ENSG00000196504 ENSG00000109606 ENSG00000163159 ENSG00000108654 ENSG00000136807 ENSG00000141867 ENSG00000105486 ENSG00000131876 ENSG00000100028 ENSG00000099995 ENSG00000077312 ENSG00000136504 ENSG00000146007 ENSG00000127337 ENSG00000196367 ENSG00000277707 ENSG00000163875 ENSG00000198231 ENSG00000165119 ENSG00000113649 ENSG00000119707 ENSG00000117360 ENSG00000179950 ENSG00000063244 ENSG00000274442 ENSG00000147274 ENSG00000125743 ENSG00000134186 ENSG00000085872 ENSG00000101161 ENSG00000115524 ENSG00000119953 ENSG00000111653 ENSG00000087365 ENSG00000132646 ENSG00000136527 ENSG00000178028 ENSG00000120616 ENSG00000096717 ENSG00000183495 ENSG00000175792 PMC5801050__F3 Cullin 3-based ubiquitin ligases as master regulators of mammalian cell differentiation ENSG00000121067 ENSG00000168036 PMC10937391__F9 Hypotheses on the mechanistical/functional involvement of each microRNA and its potential mRNA targets on OPC differentiation ENSG00000197971 ENSG00000149269 ENSG00000010810 ENSG00000177606 ENSG00000084733 ENSG00000124920 ENSG00000133818 PMC9162454__F2 Pyroptosis is executed by the gasdermin pore-forming family of proteins ENSG00000278718 ENSG00000163568 ENSG00000167914 ENSG00000147697 ENSG00000073605 ENSG00000026103 PMC3874794__F2 An outline of the GPI and GPI-anchored protein biosynthetic pathway ENSG00000143315 ENSG00000101464 PMC4601220__F1 RNAi pathways in insects ENSG00000092847 ENSG00000113360 ENSG00000123908 ENSG00000132341 PMC3018616__F1 TGFB superfamily signaling pathway ENSG00000170365 ENSG00000137834 ENSG00000122194 PMC4539294__F2 Schematic of the itch spinal cord circuit.The initial stages of the itch-circuit in the spinal cord are characterized by the expression of neuropeptides and the post-synaptic expression of their cognate receptors ENSG00000078747 ENSG00000157005 ENSG00000120937 PMC4743801__F3 The globo-series pathway in human ENSG00000183778 PMC9367932__F1 Macrophage Phenotypes in Normal and Diabetic Wound Healing and Therapeutic Interventions ENSG00000116031 ENSG00000108691 ENSG00000121807 ENSG00000115009 ENSG00000112486 PMC8911152__F2 New Perspective on Thyroid Hormones: Crosstalk with Reproductive Hormones in Females ENSG00000174417 ENSG00000165409 ENSG00000170893 ENSG00000168610 PMC8549629__F8 Siglec-8 Signals Through a Non-Canonical Pathway to Cause Human Eosinophil Death In Vitro ENSG00000038382 ENSG00000156299 ENSG00000149269 ENSG00000010671 PMC9475358__F2 Tumor and Metastasis Initiation by Chemokine Receptors ENSG00000107562 ENSG00000128602 ENSG00000121966 PMC11611719__F7 Schematic model indicates that ozone promotes macrophage efferocytosis and alleviates neuropathic pain ENSG00000153208 PMC8023146__F1 African Swine Fever Virus MGF-505-7R Negatively Regulates cGAS–STING-Mediated Signaling Pathway ENSG00000177169 ENSG00000183735 ENSG00000164430 PMC4963810__F1A Ptk7 and Mcc, Unfancied Components in Non-Canonical Wnt Signaling and Cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9330518__SF1 Co-delivery of phagocytosis checkpoint and STING agonist by a Trojan horse nanocapsule for orthotopic glioma immunotherapy ENSG00000198053 PMC9139855__F2 Current Therapeutic Landscape and Safety Roadmap for Targeting the Aryl Hydrocarbon Receptor in Inflammatory Gastrointestinal Indications ENSG00000140505 ENSG00000140465 ENSG00000106546 ENSG00000104368 PMC8688453__F1 Mitophagy process ENSG00000215021 ENSG00000158828 ENSG00000069509 PMC8134040__F7 EphA2–YES1–ANXA2 pathway in GC growth and progression ENSG00000182718 ENSG00000142627 ENSG00000136997 ENSG00000176105 ENSG00000168610 PMC6712457__F3 Linc00152 promotes the proliferation of gastric cancer cells by regulating the PI3K/AKT signaling pathway ENSG00000002330 ENSG00000005882 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC6600655__F1 Agent that activates the cascade in the MAPK pathway, which can lead to TJs opening or assembly ENSG00000019991 ENSG00000137673 ENSG00000138798 ENSG00000166278 PMC9688352__F1 Macrophages and Wnts in Tissue Injury and Repair ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000177606 ENSG00000168036 PMC6712457__F1 Linc00152 promotes the proliferation of HCC cells by activating the mTOR signaling pathway ENSG00000002330 ENSG00000005882 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC5793041__F6 Integrative view of DENV-induced metabolic alterations in hepatic cells ENSG00000042832 ENSG00000169710 PMC2963103__F1 Normal biology of the VHL-HIF axis in the setting of (A) normoxia and (B) hypoxia ENSG00000162889 ENSG00000134086 ENSG00000163235 ENSG00000198793 ENSG00000146648 ENSG00000114738 PMC3299304__F3 Molecular mechanisms of HGF-c-Met-mediated signaling for inhibiting TLR4-mediated NFKB activation in macrophages ENSG00000019991 ENSG00000136869 PMC6538558__F3 Three example models in the CODA-ML format ENSG00000132906 ENSG00000150991 ENSG00000135446 ENSG00000136997 ENSG00000123374 ENSG00000077782 ENSG00000146648 PMC7479313__F15 Signaling Pathways of E2Fs in Gastric Cancer (TGFB Signaling Pathway) ENSG00000165556 ENSG00000175054 ENSG00000019991 ENSG00000134982 ENSG00000164362 ENSG00000164690 ENSG00000171791 ENSG00000293532 ENSG00000122008 PMC7012489__F1 Canonical and non-canonical nuclear factor kappaB pathways ENSG00000023445 ENSG00000171791 PMC5518632__F3 NLRC5/CITA: a key player in cancer immune surveillance ENSG00000224320 PMC4418510__F1 Canonical TNFR to Nf-kB pathway ENSG00000137275 ENSG00000102871 ENSG00000083799 ENSG00000175104 ENSG00000127191 PMC7072652__F2 Failure of major homeostatic mechanisms contributes to senescence onset ENSG00000142192 ENSG00000198793 ENSG00000096717 PMC12236747__F3 Indole metabolites induce neuroinflammation through the AHR and NTS pathways ENSG00000120833 ENSG00000163235 ENSG00000142166 ENSG00000106546 PMC5735681__F1 Different proteins on the Wnt signaling pathway ENSG00000154342 ENSG00000154764 ENSG00000134982 ENSG00000168036 PMC4334449__F1 Pathogenesis of HCC and targets for chemopreventive agents ENSG00000198793 ENSG00000136997 ENSG00000123374 ENSG00000146648 PMC4618041__F7 Model depicting Dcp1-mediated translational repression in endotoxin-tolerant cells ENSG00000173933 ENSG00000136869 ENSG00000123908 PMC5735681__F3 Interaction between the Wnt and the Notch signaling pathways ENSG00000154342 ENSG00000273529 ENSG00000114315 PMC7468867__F9 The regulatory effects of foxtail millet on the progression of colitis-associated colorectal cancer (CRC) ENSG00000132646 ENSG00000049768 ENSG00000168610 ENSG00000106546 PMC5285348__F8 Mutual regulation between miRNAs and the Wnt pathway determine the survival of Mycobacterium tuberculosis (M ENSG00000134982 ENSG00000174804 ENSG00000172936 PMC5285348__F7 Nucleotide-binding oligomerization domain 2 (NOD2) and the activation of the Wnt pathway in response to Mycobacterium tuberculosis infection ENSG00000138795 ENSG00000167207 ENSG00000134982 ENSG00000168036 ENSG00000187123 PMC5313500__F2 The proposed cellular functions of cellular NLRC5 ENSG00000162711 ENSG00000088888 ENSG00000137673 ENSG00000125538 ENSG00000168036 ENSG00000175104 ENSG00000127191 ENSG00000101557 PMC5285348__F9 Beijing Mycobacterium tuberculosis (M ENSG00000138795 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000168036 ENSG00000185269 PMC7834968__F8 Schematic diagram showing how ASV alleviates silica-induced pulmonary fibrosis by regulating TGFB1/Smads pathway PMC3368918__F1 Instrumental Variable Estimation of the Causal Effect of Plasma 25-Hydroxy-Vitamin D on Colorectal Cancer Risk: A Mendelian Randomization Analysis ENSG00000111012 ENSG00000172893 ENSG00000019186 ENSG00000145321 ENSG00000186104 ENSG00000135929 PMC7201093__F1 Summary of the mechanisms that myocardial protection mediated by melatonin through receptor and non-receptor pathways ENSG00000002330 ENSG00000148400 ENSG00000116688 ENSG00000198626 ENSG00000096717 ENSG00000142082 ENSG00000069667 ENSG00000026103 PMC5285348__F3 Canonical Wnt signaling pathway ENSG00000138795 ENSG00000134982 ENSG00000168036 PMC5285348__F5 Mycobacterium tuberculosis (M ENSG00000168036 ENSG00000172936 ENSG00000136869 ENSG00000277641 ENSG00000157240 PMC7824104__F2 Nrf2 signaling ENSG00000178573 ENSG00000100387 ENSG00000113558 ENSG00000106546 ENSG00000079999 PMC8656547__F2 Emerging Role of Non-Coding RNAs in Pituitary Gland Tumors and Meningioma ENSG00000253352 ENSG00000088992 PMC6436804__F9 Summary of the toxic mechanisms of ZEA on breast cancer cell growth with antagonistic effects posted by AFB1 ENSG00000082175 ENSG00000291971 PMC10378139__F2 Ferroptosis in Cancer Progression ENSG00000124882 ENSG00000138798 ENSG00000123983 PMC5061598__F2 Proposed model for how the activation of ECM receptor pathway in the adipose tissue is linked to obesity-associated insulin resistance ENSG00000149311 ENSG00000135218 ENSG00000026508 ENSG00000100219 ENSG00000112715 PMC2835492__F4 Regulation of MUC4 expression ENSG00000157933 ENSG00000111537 ENSG00000145113 PMC4960920__F1 Schema of upstream and downstream signaling pathways of mTORC1 PMC3336023__F3 Chronic alcohol exposure alters gene expression in HepG2 cells ENSG00000110799 ENSG00000102871 ENSG00000198793 ENSG00000163064 ENSG00000127191 ENSG00000132693 ENSG00000185010 ENSG00000106927 ENSG00000180210 ENSG00000152684 ENSG00000113905 ENSG00000145623 ENSG00000145192 ENSG00000171560 PMC4073278__F7 The changes that are induced in cells by a deficiency of RPs ENSG00000149311 ENSG00000175054 ENSG00000196839 ENSG00000198793 PMC5192018__F3 Pubertal development and regulation ENSG00000109163 ENSG00000170498 PMC3336023__F4 Chronic alcohol exposure alters gene expression in HepG2 cells ENSG00000128272 ENSG00000178573 ENSG00000095321 ENSG00000177606 ENSG00000167996 ENSG00000165280 ENSG00000125656 ENSG00000023909 PMC3209136__F2 Biosynthetic pathway for UA and flocculosin ENSG00000083857 ENSG00000165323 PMC4621504__F3 Whole Exome Sequencing Identifies Frequent Somatic Mutations in Cell-Cell Adhesion Genes in Chinese Patients with Lung Squamous Cell Carcinoma ENSG00000172680 ENSG00000134982 ENSG00000198793 ENSG00000134308 ENSG00000168036 ENSG00000122025 ENSG00000186575 ENSG00000196712 ENSG00000134376 ENSG00000113645 ENSG00000126016 ENSG00000157764 ENSG00000116044 ENSG00000198561 ENSG00000150457 ENSG00000131023 ENSG00000151718 ENSG00000079999 ENSG00000066468 ENSG00000117020 ENSG00000047644 ENSG00000160867 ENSG00000134853 ENSG00000168646 ENSG00000146648 ENSG00000178568 PMC4593065__F1 The IGF-1R signaling network and nodes of therapeutic blockade ENSG00000171105 ENSG00000002330 ENSG00000197081 ENSG00000169047 ENSG00000198793 ENSG00000140443 PMC6034147__F1 Wnt signaling ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000277641 ENSG00000136826 PMC5821264__F3 Regulation of Signal Transduction by DJ-1 ENSG00000134086 PMC5821264__F2 Regulation of Signal Transduction by DJ-1 ENSG00000291971 PMC3295899__F2 Matricellular Protein Thrombospondin-1 Globally Regulates Cardiovascular Function and Responses to Stress via CD47 ENSG00000291971 PMC8491165__F1 Sphingolipid biosynthetic pathway leading to ceramide and sphingosine 1-phosphate (S1P) formation ENSG00000170989 ENSG00000180739 ENSG00000213694 ENSG00000125910 ENSG00000267534 ENSG00000183018 ENSG00000102172 PMC3929000__F1 TRAIL signalling induces the extrinsic apoptotic pathway ENSG00000178860 ENSG00000168040 PMC5821264__F1 Regulation of Signal Transduction by DJ-1 ENSG00000087245 ENSG00000198793 ENSG00000100985 PMC9456528__F2 DNA Holliday Junction: History, Regulation and Bioactivity ENSG00000154920 ENSG00000188827 ENSG00000051180 PMC7917047__F5 Possible signaling pathway of MbovP280-induced apoptosis in BoMac ENSG00000132906 ENSG00000142192 ENSG00000164305 PMC3989838__F1 Insulin effects on endothelial cells ENSG00000138336 ENSG00000198793 ENSG00000140443 PMC8525369__F1 Gene Editing of Hematopoietic Stem Cells: Hopes and Hurdles Toward Clinical Translation ENSG00000015285 ENSG00000187741 PMC4920139__F1 Genes represented in the 38-gene DTC panel and their biological pathway associations ENSG00000133937 ENSG00000117425 ENSG00000119888 ENSG00000173641 ENSG00000129514 ENSG00000104332 ENSG00000135480 ENSG00000171345 ENSG00000110484 ENSG00000124216 ENSG00000106571 ENSG00000160867 ENSG00000122691 ENSG00000092208 ENSG00000141753 ENSG00000019549 ENSG00000152137 ENSG00000164093 ENSG00000128602 PMC7872472__F1 Metabolism, pharmacokinetics and selected pharmacodynamic effects of codeine following a single oral administration to horses ENSG00000171234 PMC2723760__F4 HERPUD1 Ingenuity Pathway Analysis illustrates interactions between indicated proteins ENSG00000178607 ENSG00000065911 ENSG00000139644 ENSG00000165030 ENSG00000156127 ENSG00000105516 ENSG00000100219 ENSG00000107175 ENSG00000163479 ENSG00000146701 ENSG00000075239 ENSG00000070669 PMC8651476__F2 Interleukin-36 Cytokines in Infectious and Non-Infectious Lung Diseases ENSG00000174125 ENSG00000187554 ENSG00000136696 ENSG00000136694 ENSG00000136869 ENSG00000276561 ENSG00000136688 ENSG00000164342 PMC3472623__F1 Folate metabolic pathway ENSG00000228716 ENSG00000124275 ENSG00000116984 PMC6608078__F2 PI3K/PTEN/AKT pathway dysregulation in prostate tumor cells ENSG00000100219 PMC3733450__F2 Kaposi’s Sarcoma-Associated Herpesvirus G Protein Coupled Receptor: Lessons on Dysregulated Angiogenesis from a Viral Oncogene ENSG00000134086 ENSG00000106617 ENSG00000198793 PMC8992550__F1 Radiotherapy and the cellular DNA damage response: current and future perspectives on head and neck cancer treatment ENSG00000012048 ENSG00000051180 ENSG00000138385 PMC8625721__F1 NLRP3 Inflammasome in Lupus Nephritis ENSG00000162711 ENSG00000109320 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC8375436__F7 Key Gene and Functional Pathways Identified in Unexplained Recurrent Spontaneous Abortion Using Targeted RNA Sequencing and Clinical Analysis ENSG00000159128 ENSG00000138378 ENSG00000111537 ENSG00000105397 ENSG00000115415 ENSG00000107485 ENSG00000168610 PMC12246121__F8 Distinct signaling pathways in the recognition of PAMPs and DAMPs by PRRs ENSG00000278718 ENSG00000174125 ENSG00000239732 ENSG00000164430 ENSG00000187554 ENSG00000163568 ENSG00000172936 ENSG00000136869 ENSG00000198626 ENSG00000127666 ENSG00000276561 ENSG00000164342 PMC5112586__F1 Histiocytic Neoplasms in the Era of Personalized Genomic Medicine ENSG00000157764 ENSG00000169047 ENSG00000095015 ENSG00000115904 PMC12246121__F9 Transcriptional regulation in PRRs-mediated inflammatory response ENSG00000065833 ENSG00000136869 ENSG00000069956 ENSG00000082212 PMC6271622__F1 Regulation of antioxidant and detoxifying genes by the NRF2-Keap1 pathway ENSG00000175793 ENSG00000079999 PMC12246121__F4 Signaling pathways mediated by iPRRs and their regulation ENSG00000181847 ENSG00000291918 PMC3302843__F10 Hypoxia Reduces Arylsulfatase B Activity and Silencing Arylsulfatase B Replicates and Mediates the Effects of Hypoxia ENSG00000108821 PMC12246121__F3 Structure of different PRRS in the cytoplasm and nucleus ENSG00000278718 ENSG00000122566 ENSG00000162711 ENSG00000183735 ENSG00000164430 ENSG00000163568 ENSG00000167325 ENSG00000160703 ENSG00000171848 ENSG00000276561 ENSG00000276068 PMC3118552__F7 Activation of the Stress Protein Response Inhibits the STAT1 Signaling Pathway and iNOS function in Alveolar Macrophages: Role of Hsp90 and Hsp70 ENSG00000115415 PMC8750665__F10 Cherry Polyphenol Extract Ameliorated Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice by Suppressing Wnt/Beta-Catenin Signaling Pathway ENSG00000134982 ENSG00000168036 PMC3334709__F4 Tau neuroinflammatory cascade ENSG00000125538 ENSG00000129226 PMC7273093__F2 COVID‐19 and heart failure: from infection to inflammation and angiotensin II stimulation. Searching for evidence from a new disease ENSG00000130234 ENSG00000137509 PMC3697769__F2 Signaling pathways activated in cord blood-derived CD34pos hematopoietic progenitor cells (upper panel) and in erythroblasts at day 6 of differentiation (erythroblasts, lower panel) ENSG00000169291 ENSG00000002330 ENSG00000148400 ENSG00000134057 ENSG00000150907 ENSG00000198793 ENSG00000155792 ENSG00000099942 PMC12246121__F2 Structure of different PRRS in the cell membrane and the extracellular ENSG00000172322 ENSG00000166523 ENSG00000203710 ENSG00000197992 ENSG00000172936 ENSG00000150455 ENSG00000163661 ENSG00000276561 ENSG00000132693 ENSG00000165471 PMC12246121__F1 Key discoveries in PRRs ENSG00000164430 ENSG00000091592 ENSG00000136869 PMC3703662__F6 Proposed model for NV-128-induced casapase-independent cell death in OCSCs ENSG00000198793 PMC4043860__F2 Transcriptional control of spermatogonial maintenance and differentiation ENSG00000244405 ENSG00000150907 ENSG00000204531 ENSG00000185668 ENSG00000172201 PMC7746952__F1 PAR1 functions in thrombotic and inflammatory processes in the vascular endothelium ENSG00000110799 ENSG00000134982 PMC3814888__F5 Mitochondrial activity pathway ENSG00000132906 ENSG00000158828 ENSG00000164305 ENSG00000115317 PMC4685214__F1 Signaling pathways leading to gonadotropin-induced activation of MAPK3/1 in preovulatory follicles or cultured cumulus-oocyte complexes ENSG00000170961 ENSG00000082175 ENSG00000172216 ENSG00000109321 ENSG00000291971 ENSG00000124882 ENSG00000163661 ENSG00000073756 ENSG00000146648 ENSG00000123610 PMC11019835__F1 Canonical and non-canonical function of CD55 ENSG00000012048 ENSG00000087245 ENSG00000039537 ENSG00000113600 ENSG00000138798 ENSG00000136997 ENSG00000168036 ENSG00000196352 ENSG00000166278 ENSG00000100985 ENSG00000168610 PMC10151533__F2 Developmental origin of tendon diversity in Drosophila melanogaster ENSG00000154134 ENSG00000185008 ENSG00000146648 PMC10944957__F1 TGFB superfamily signaling pathway and the potential therapeutic targets in pancreatic cancer ENSG00000170365 PMC7712978__F2 P53-AB feedback loop revisited ENSG00000142192 ENSG00000198793 ENSG00000077463 PMC8266896__F7 EGR1 and RXRA transcription factors link TGFB pathway and CCL2 expression in triple negative breast cancer cells ENSG00000108691 PMC8292865__F2 Epigenetically inactivated RASSF1A as a tumor biomarker ENSG00000278268 ENSG00000134982 ENSG00000145386 ENSG00000117399 PMC6921210__F7 GEFT function and signalling pathway ENSG00000070831 PMC9120431__F3 Engineering GD T Cells: Recognizing and Activating on Their Own Way ENSG00000112977 ENSG00000291603 ENSG00000111537 ENSG00000101146 ENSG00000292170 ENSG00000132646 ENSG00000173599 ENSG00000204520 ENSG00000141968 PMC3625500__F5 Overview on the mechanisms of glutathione induced cell death ENSG00000120868 ENSG00000168040 PMC6985072__F6 Working hypothesis ENSG00000138798 ENSG00000111816 ENSG00000146648 PMC10751671__F1 Impact of Physical Exercise on Melanoma Hallmarks: Current Status of Preclinical and Clinical Research ENSG00000198793 ENSG00000112715 ENSG00000162692 PMC10751671__F2 Impact of Physical Exercise on Melanoma Hallmarks: Current Status of Preclinical and Clinical Research ENSG00000111537 ENSG00000168610 PMC7762563__F3 Ang-TIE therapeutics against diabetic retinal diseases ENSG00000150907 ENSG00000163914 ENSG00000112715 PMC7762563__F2 Angiopoietin–TIE signaling pathway in the vascular endothelium ENSG00000150907 ENSG00000163914 PMC8720003__F9 Study on the Mechanism of Acori Graminei Rhizoma in the Treatment of Alzheimer's Disease Based on Network Pharmacology and Molecular Docking ENSG00000142192 ENSG00000171105 ENSG00000082175 ENSG00000198793 ENSG00000160182 ENSG00000087085 ENSG00000168040 ENSG00000064012 ENSG00000164305 ENSG00000196689 PMC4220655__F2 Selective autophagy in respiratory infection and sepsis ENSG00000162711 ENSG00000123576 ENSG00000125538 ENSG00000136869 ENSG00000237693 PMC4375782__F8 Interplay between glucose and leptin signaling determines the strength of GABAergic synapses at POMC neurons ENSG00000115138 ENSG00000168610 PMC5679204__F7 Matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1 ENSG00000188747 PMC5374883__F11 Proposed pathway of TGFB2–TLR4 signaling crosstalk in the glaucomatous TM ENSG00000095739 ENSG00000172936 ENSG00000136869 PMC5136496__F1 Apoptotic pathways ENSG00000120868 PMC8135047__F1 Metabolic profiling in serum, cerebrospinal fluid, and brain of patients with cerebrotendinous xanthomatosis ENSG00000148798 PMC8263657__F4 Basic approaches, challenges and opportunities for the discovery of small molecule anti-tumor drugs ENSG00000104689 ENSG00000002330 ENSG00000120889 ENSG00000168040 ENSG00000026103 PMC5329138__F2 Cross-Talk between the Cytoplasmic RIG-I and STING Sensing Pathways ENSG00000088888 ENSG00000131323 ENSG00000175104 ENSG00000142166 PMC7276545__F2 Examples of life science networks ENSG00000090402 PMC4320971__F2 Sphingolipid metabolites in inflammatory disease ENSG00000100422 ENSG00000063176 PMC4320971__F1 Sphingolipid metabolites in inflammatory disease ENSG00000100422 ENSG00000172057 ENSG00000102172 PMC11767564__F2 Metabolic or disease regulation by LEAP-2 antagonism of GHSR1a in human organs ENSG00000164406 ENSG00000108691 ENSG00000198793 ENSG00000108821 ENSG00000135324 PMC4680864__F3 Proteome Analysis of Ground State Pluripotency ENSG00000067057 ENSG00000175793 ENSG00000198793 ENSG00000105953 ENSG00000159399 PMC7924645__F2 MSH biosynthesis and regulation in actinomycetes ENSG00000116984 PMC5069291__F1 Schematic model of the Wnt/beta-catenin pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5069291__F2 Schematic model of the Wnt/beta-catenin pathway in Alzheimer disease ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8063228__F6 Regulatory function of peroxiredoxin I on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung cancer development ENSG00000002330 ENSG00000132646 ENSG00000040199 PMC4125356__F7 MicroRNA miR-150 modulates the expression of GAB1 and FOXP1 that are involved in BCR-signaling pathway in CLL B cells ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000197943 PMC11312688__F3 Proposed Rearticulation of the Mechanism for Radiation-Induced Fibrosis: Initial radiation exposure initiates at least three distinct pathways ENSG00000111537 ENSG00000137857 ENSG00000137033 ENSG00000140279 ENSG00000086991 ENSG00000074771 ENSG00000138385 PMC2972642__F2 REVIEW: Oxytocin: Crossing the Bridge between Basic Science and Pharmacotherapy ENSG00000180210 ENSG00000171105 ENSG00000167658 ENSG00000081189 PMC11312688__F2 Radiation Induced Skin Fibrosis (RISF): Opportunity for Angiotensin II-Dependent Intervention ENSG00000130234 ENSG00000096717 ENSG00000079999 PMC3292920__F1 Diagram shows the enzyme points (in cycle) on which the effects of n-3 PUFA might operate in the homocysteine metabolic pathway of relevance ENSG00000205221 ENSG00000116984 PMC8223458__F5 Long non‐coding RNA HOTAIR/microRNA‐761 sponge regulates PPME1 and further influences cell biological functions in thyroid carcinoma ENSG00000123908 PMC5040593__F3 Four pathways for double-stranded break (DSB) repair.Nascent DSBs are first recognized by ATM and the MRN complex that initiate a series of DNA damage response events that aim at arresting cell cycle and recruiting DSB repair proteins ENSG00000143799 ENSG00000012048 ENSG00000080345 ENSG00000291803 ENSG00000165392 ENSG00000139618 PMC5859976__F1 Screenshot of PathwayMapper ENSG00000124102 ENSG00000109452 ENSG00000117020 ENSG00000002330 ENSG00000143622 ENSG00000281877 ENSG00000169032 ENSG00000146648 ENSG00000140443 PMC11587691__F1 Glucose metabolism in cancer cells ENSG00000180210 ENSG00000198793 ENSG00000183684 ENSG00000168610 PMC11587691__F2 Lipid metabolic pathway ENSG00000131473 ENSG00000135423 ENSG00000135218 ENSG00000134824 ENSG00000113161 ENSG00000099194 ENSG00000026103 PMC8440458__F2 Farnesoid X Receptor (FXR) agonists in non-alcoholic hepatitis ENSG00000160867 ENSG00000167910 PMC12042381__F1 Neospora caninuminfection induced significant changes of metabolic profiles in caprine EECs ENSG00000074800 ENSG00000188316 ENSG00000105953 ENSG00000169299 PMC5341794__F1 PD-1 signaling ENSG00000291603 ENSG00000134982 PMC6538535__F3 Menin-associated pathways with potential targeted therapies ENSG00000180447 ENSG00000130522 ENSG00000198793 ENSG00000115904 ENSG00000168036 ENSG00000157005 ENSG00000168646 PMC4259948__F1 Schematic summary of the molecular mechanisms of HLJ1 in suppressing lung cancer tumourigenesis ENSG00000100811 ENSG00000087245 ENSG00000181163 ENSG00000130522 ENSG00000060982 ENSG00000122786 ENSG00000265972 ENSG00000124762 ENSG00000285069 ENSG00000138764 ENSG00000115415 ENSG00000137203 ENSG00000026508 PMC6458279__F5 Overview of the ferroptosis pathway and potential targets for pharmacological inhibition ENSG00000167468 PMC4525315__F8 Model representing the implication of the GSK-3/Beta-catenin axis in IRF3-regulated RLR-dependent antiviral innate immunity ENSG00000183735 ENSG00000088888 ENSG00000105723 PMC8740689__F1 Multipurpose Drugs Active Against Both Plasmodium spp. and Microorganisms: Potential Application for New Drug Development ENSG00000228716 ENSG00000095059 ENSG00000173599 PMC7536827__F2 Proteins associated with neurotoxicity and neurodegeneration ENSG00000226492 ENSG00000198793 PMC6458279__F7 Autophagy pathway and potential targets for pharmacological modulation ENSG00000152348 ENSG00000042832 ENSG00000112561 ENSG00000145782 ENSG00000057663 PMC6458279__F1 Apoptosis pathway and potential targets for pharmacological modulation ENSG00000135218 ENSG00000002330 ENSG00000136869 ENSG00000168040 ENSG00000115317 PMC4296672__F7 Estrogen Receptor-alpha 36 Mediates the Anti-apoptotic Effect of Estradiol in Triple Negative Breast Cancer Cells via a Membrane-Associated Mechanism ENSG00000173599 ENSG00000198670 ENSG00000171517 PMC5776175__F9 Model for Brucella Omp25 modulation of tumor necrosis factor (TNF)A suppression in porcine and murine macrophages ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC7156766__F5 Purine alkaloid metabolic pathway ENSG00000198931 PMC2829054__F7 Cdk2 Is Required for p53-Independent G2/M Checkpoint Control ENSG00000175054 ENSG00000164053 ENSG00000094804 ENSG00000123374 PMC8087567__F1 How the love of muscle can break a heart: Impact of anabolic androgenic steroids on skeletal muscle hypertrophy, metabolic and cardiovascular health ENSG00000169047 ENSG00000146648 PMC8138133__F6 Cox4i2 Triggers an Increase in Reactive Oxygen Species, Leading to Ferroptosis and Apoptosis in HHV7 Infected Schwann Cells ENSG00000168003 ENSG00000151012 ENSG00000167468 PMC7536388__F7 Interrelations between profibrotic Smad2/3-dependent and anti-fibrotic Smad1/5/(8)9-dependent pathways in HBFs ENSG00000170365 ENSG00000145321 PMC9563963__F3 Long Noncoding RNAs and Circular RNAs Regulate AKT and Its Effectors to Control Cell Functions of Cancer Cells ENSG00000117020 ENSG00000253352 PMC6676114__F6 RNA MODOMICS and heterogeneity of tumors ENSG00000149658 ENSG00000198492 ENSG00000136997 ENSG00000171791 ENSG00000146648 PMC6132177__F1 Autophagy pathway ENSG00000177169 ENSG00000198382 ENSG00000083290 ENSG00000198793 ENSG00000115718 PMC9131992__F4 Non-structural proteins of bovine viral diarrhea virus ENSG00000088888 PMC9655337__F6 Preventive Mechanism of Lycopene on Intestinal Toxicity Caused by Cyclophosphamide Chemotherapy in Mice by Regulating TLR4-MyD88/TRIF-TRAF6 Signaling Pathway and Gut-Liver Axis ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC7605157__F2 Mechanisms responsible for the cytoprotective and antiinflammatory effects of PARP inhibitors in nononcological diseases ENSG00000149311 ENSG00000118518 ENSG00000108691 ENSG00000177606 ENSG00000227345 PMC3281082__F7 ER Stress Negatively Modulates the Expression of the miR-199a/214 Cluster to Regulates Tumor Survival and Progression in Human Hepatocellular Cancer ENSG00000198793 PMC11671467__F3 EGCG-Mediated Pathways Targeting Oxidative Stress ENSG00000114315 PMC5576431__F3 Downregulation of the neurotrophin-MAPK signaling pathway in DPN ENSG00000002330 PMC11671467__F5 EGCG in inhibition of cancer growth ENSG00000198793 PMC11375560__F4 LOX activity in promoting tumour progression in breast cancer ENSG00000291971 ENSG00000168487 ENSG00000168610 PMC5729532__F3 P53–p21–DREAM–E2F/CHR pathway ENSG00000112242 ENSG00000133740 ENSG00000205250 ENSG00000124762 ENSG00000282899 PMC3775648__F4 Major elements of the Rho signaling pathway ENSG00000284816 ENSG00000089820 PMC12086034__F4 Visualize the KEGG enrichment results and mark the positions of hub genes ENSG00000132906 ENSG00000142192 ENSG00000136457 ENSG00000002330 ENSG00000069482 ENSG00000198793 ENSG00000198517 ENSG00000145321 ENSG00000112715 PMC7767789__F3 Metabolic abnormalities induced by hyperglycemia PMC5364987__F2 Different pathogenic roles of ER-resident and cell surface HLA-B27 dimers ENSG00000162594 ENSG00000284213 ENSG00000273686 PMC6387347__F1 One proposed mechanism for how vascular endothelial growth factor/neuropilin (VEGF/NRP) signaling impacts cancer stem cell (CSC) function independently of VEGFRs ENSG00000168283 ENSG00000118257 PMC6046285__F1 Major signaling pathways activated through IGF-1R and EGF-R in adrenocortical carcinoma ENSG00000197081 ENSG00000138798 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC8201055__F2 microRNAs in the Regulation of Melanogenesis ENSG00000168036 ENSG00000107165 PMC3046768__F2 Schematic of the base excision repair pathways present in mitochondria ENSG00000138346 PMC3775648__F1 Major elements of the canonical Wnt signaling pathway ENSG00000154764 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000188064 ENSG00000183762 ENSG00000169884 ENSG00000168036 ENSG00000061492 ENSG00000125084 ENSG00000157240 ENSG00000163251 ENSG00000155011 ENSG00000104371 ENSG00000134245 ENSG00000177283 ENSG00000155760 ENSG00000276799 ENSG00000162552 ENSG00000154342 ENSG00000107404 ENSG00000156076 ENSG00000174804 ENSG00000002745 ENSG00000277641 ENSG00000050165 ENSG00000188763 PMC10889208__F1 Heterogeneity of the dermal fibroblast population ENSG00000144749 ENSG00000140285 ENSG00000134853 ENSG00000166147 PMC9461128__F5 Regulatory role of AP-2B in monoaminergic neurotransmitter systems: insights on its signalling pathway, linked disorders and theragnostic potential ENSG00000153885 ENSG00000134504 ENSG00000127337 PMC3775648__F3 Major elements of the noncanonical Wnt/Ca2+signaling pathway ENSG00000102908 ENSG00000167083 ENSG00000149782 ENSG00000176533 ENSG00000088256 ENSG00000174021 ENSG00000242616 ENSG00000114349 ENSG00000163558 ENSG00000214415 ENSG00000166501 ENSG00000197943 ENSG00000124181 ENSG00000184304 ENSG00000101333 ENSG00000162188 ENSG00000167414 ENSG00000127928 ENSG00000027075 ENSG00000114450 ENSG00000188386 ENSG00000156049 ENSG00000172380 ENSG00000078369 ENSG00000127955 ENSG00000060558 ENSG00000087460 ENSG00000161714 ENSG00000065135 ENSG00000120910 ENSG00000120063 ENSG00000221823 ENSG00000138193 ENSG00000148660 ENSG00000067606 ENSG00000127588 ENSG00000285485 ENSG00000115825 ENSG00000145349 ENSG00000069966 PMC9461128__F3 Regulatory role of AP-2B in monoaminergic neurotransmitter systems: insights on its signalling pathway, linked disorders and theragnostic potential ENSG00000123454 ENSG00000141744 PMC3775648__F2 Major elements of the noncanonical PCP Wnt signaling pathway ENSG00000163637 ENSG00000162552 ENSG00000107404 ENSG00000169071 ENSG00000050748 ENSG00000130758 ENSG00000173218 ENSG00000095015 ENSG00000065559 ENSG00000185483 ENSG00000142733 ENSG00000139625 ENSG00000135341 ENSG00000006062 ENSG00000173327 ENSG00000169967 ENSG00000073803 ENSG00000100592 ENSG00000143126 ENSG00000111186 ENSG00000008300 ENSG00000146122 PMC7768045__F4 Intramembrane proteolysis in cancer related signaling ENSG00000137845 ENSG00000178568 PMC9461128__F2 Regulatory role of AP-2B in monoaminergic neurotransmitter systems: insights on its signalling pathway, linked disorders and theragnostic potential ENSG00000179862 ENSG00000125931 ENSG00000150991 ENSG00000132872 ENSG00000008196 ENSG00000136997 ENSG00000134504 ENSG00000127337 PMC5055500__F2 Diagrammatic illustrations of CCN1 signaling involved pancreatic cancer progression via CCN1-Notch1-SHh axes ENSG00000118816 ENSG00000164690 ENSG00000128602 PMC7858151__F8 MAPs alleviates AFB1-induced bursa of Fabricius injury by regulating redox and apoptotic signaling pathway in broilers ENSG00000079999 PMC5357196__F3 Biosynthesis of the methylthioxylose capping motif of lipoarabinomannan in Mycobacterium tuberculosis ENSG00000124479 ENSG00000291814 PMC2902700__F6 GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE STIMULATES THE PROLIFERATION OF COLORECTAL CANCER CELLS ENSG00000159224 ENSG00000198793 ENSG00000010310 PMC6213986__F2 Pharmacodynamic mechanism of TCM against HSV-1 ENSG00000088888 ENSG00000102034 ENSG00000198793 ENSG00000164342 PMC6363022__F1 Summary of interactions between ECM remodelling and kinase activity ENSG00000162733 ENSG00000291971 ENSG00000138798 ENSG00000163914 ENSG00000026508 ENSG00000168610 ENSG00000146648 ENSG00000166033 PMC6199805__F5 GABAergic synapse signaling pathway, with the enriched target genes highlighted in red PMC7381633__F6 Upregulation of OSBPL3 by HIF1A promotes colorectal cancer progression through activation of RAS signaling pathway ENSG00000070882 ENSG00000163914 PMC5817864__F1 Rapidly induced cell autonomous bypass signaling ENSG00000066468 ENSG00000168610 ENSG00000146648 PMC7346753__F2 Multiple targets and multiple signal pathways of Huang Qin-Bai Shao (HQ-BS) herb pair against cancer ENSG00000050628 ENSG00000170214 ENSG00000248144 ENSG00000007908 ENSG00000171791 ENSG00000112715 ENSG00000043591 ENSG00000073756 ENSG00000102468 ENSG00000274542 ENSG00000007171 ENSG00000132170 ENSG00000090316 ENSG00000133019 ENSG00000108691 ENSG00000184845 ENSG00000084676 ENSG00000128052 ENSG00000177606 ENSG00000123374 PMC7481593__F2 Ferroptosis modulation in tumor ENSG00000156873 ENSG00000168003 ENSG00000151012 ENSG00000125144 ENSG00000167468 ENSG00000167996 ENSG00000122873 ENSG00000136381 ENSG00000079999 PMC3465072__F1 Crowdsourcing Network Inference: The DREAM Predictive Signaling Network Challenge ENSG00000163235 ENSG00000169047 ENSG00000095015 ENSG00000175104 ENSG00000127191 ENSG00000146648 PMC7481593__F1 Ferroptosis ENSG00000168003 ENSG00000196839 ENSG00000167468 ENSG00000113161 ENSG00000111684 ENSG00000115107 ENSG00000136381 PMC9038189__F5 Cyst lineage recovery after ablation ENSG00000138798 ENSG00000146648 PMC8561869__F2 FoxO transcription factors in aging and age-related metabolic and neurodegenerative diseases ENSG00000169047 ENSG00000133124 PMC9026172__F5 Pharmacodynamics, Network Pharmacology, and Pharmacokinetics of Chinese Medicine Formula 9002A in the Treatment of Alzheimer’s Disease ENSG00000122420 ENSG00000070831 ENSG00000140505 ENSG00000087085 ENSG00000196591 ENSG00000101266 ENSG00000148344 ENSG00000118777 ENSG00000196396 ENSG00000164305 ENSG00000106546 ENSG00000112038 ENSG00000170890 ENSG00000239732 ENSG00000171720 ENSG00000165841 ENSG00000140379 ENSG00000196549 ENSG00000132906 ENSG00000142192 ENSG00000188822 ENSG00000081237 ENSG00000100448 ENSG00000116329 ENSG00000173039 ENSG00000164082 ENSG00000036828 ENSG00000073756 ENSG00000102468 ENSG00000267534 ENSG00000007171 ENSG00000132170 ENSG00000186810 ENSG00000164362 ENSG00000125910 ENSG00000096717 PMC9628328__F1 IRAK1 Duplication in MECP2 Duplication Syndrome Does Not Increase Canonical NFKB–Induced Inflammation ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC2696328__F5 Proposed model for the effect of HPTE in the granulosa cell ENSG00000168066 ENSG00000168036 ENSG00000140443 PMC550674__F2 Apoptosis mediated by death receptors requires the FADD adaptor molecule ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC3130335__F1 MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells ENSG00000169047 ENSG00000146648 ENSG00000140443 PMC8487456__F4 Quality control and recycling of peptidyl-tRNAs on stalled ribosomes ENSG00000284774 ENSG00000291534 ENSG00000163516 ENSG00000072756 ENSG00000165525 ENSG00000141642 PMC5802164__F6 Kyoto Encyclopedia of Genes and Genomes pathway of hsa04622: RIG-I-like receptor signaling pathway ENSG00000163512 ENSG00000187608 ENSG00000102871 ENSG00000095015 ENSG00000135341 ENSG00000057663 ENSG00000052723 ENSG00000183735 ENSG00000088888 ENSG00000263528 ENSG00000160703 ENSG00000198933 ENSG00000145782 ENSG00000064012 ENSG00000215301 ENSG00000100906 ENSG00000109320 ENSG00000269335 ENSG00000115267 ENSG00000213341 ENSG00000168040 ENSG00000127191 ENSG00000276561 ENSG00000101695 ENSG00000127445 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000121060 PMC371122__F7 Signaling pathway of UCP1 transcription in brown fat PMC8118165__F1 Pembrolizumab in unresectable or metastatic MSI-high colorectal cancer: safety and efficacy ENSG00000089692 ENSG00000168036 PMC3141076__F6 Integrated Expression Profiling and Genome-Wide Analysis of ChREBP Targets Reveals the Dual Role for ChREBP in Glucose-Regulated Gene Expression ENSG00000262785 ENSG00000166391 ENSG00000005882 ENSG00000169710 ENSG00000080166 ENSG00000124253 ENSG00000062282 PMC4602327__F1 Major pathways of apoptosis ENSG00000039537 ENSG00000113600 ENSG00000002330 ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC7996143__F11 Activation of Sirt1 with SRT1720 can handle the high fructose diet-induced insulin resistance, oxidative stress, and mitochondrial dysfunction through Sirt1-PGC-1Alpha-NRF1- Sirt3-TFAM signaling pathway ENSG00000142082 ENSG00000106459 PMC2987346__F2 RSK signaling pathway ENSG00000128272 ENSG00000002330 ENSG00000167658 ENSG00000198910 PMC3522801__F2 DNA Damage Signaling Assessed in Individual Cells in Relation to the Cell Cycle Phase and Induction of Apoptosis ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000123374 ENSG00000140464 PMC6103408__F9 IFNG-induced autophagy is regulated by HMOX1 ENSG00000177169 ENSG00000111537 ENSG00000172216 ENSG00000284099 ENSG00000112561 ENSG00000128829 ENSG00000237693 PMC8005112__F2 Mechanisms of synergy between small molecules and immune checkpoint inhibition in melanoma ENSG00000157764 ENSG00000134982 PMC3522801__F1 DNA Damage Signaling Assessed in Individual Cells in Relation to the Cell Cycle Phase and Induction of Apoptosis ENSG00000188486 ENSG00000149311 ENSG00000012048 PMC7190807__F9 Hypothesis diagram of the regulatory mechanism of Twist1, Tie1, Tie2, Angs, and Akt/Foxo1 in endothelial cells ENSG00000122691 PMC4180659__F1 Perpetuation of innate immune responses in sJIA ENSG00000172936 ENSG00000175104 PMC4860843__F8 Disruption of TGF-Beta-mediated tumor suppression in SCLC cells ENSG00000139352 PMC3324026__F1 Annotation of the insulin/TOR network in Apis showing methylated and differentially methylated genes ENSG00000157764 ENSG00000198793 ENSG00000164327 PMC7022656__F9 Cross-talks between distinct signaling pathways activated within different ER-to-nuclear responsive networks to the classic ER stressor TU ENSG00000170967 ENSG00000128272 ENSG00000197312 ENSG00000144895 ENSG00000100219 ENSG00000023909 ENSG00000151092 ENSG00000106459 PMC11880501__F7 Working model ENSG00000128016 ENSG00000162337 PMC6756575__F4 Roundabout signaling pathway involved in the pathogenesis of COPD by integrative bioinformatics analysis ENSG00000177455 ENSG00000164128 ENSG00000133110 ENSG00000118785 ENSG00000108342 ENSG00000197405 ENSG00000169429 ENSG00000100985 ENSG00000127588 ENSG00000154188 ENSG00000137801 PMC6756575__F3 Roundabout signaling pathway involved in the pathogenesis of COPD by integrative bioinformatics analysis ENSG00000114200 ENSG00000168329 ENSG00000143341 ENSG00000100842 ENSG00000176971 ENSG00000173467 ENSG00000241644 ENSG00000106524 ENSG00000164764 ENSG00000155011 ENSG00000163017 ENSG00000116030 ENSG00000177508 ENSG00000291357 ENSG00000185008 ENSG00000105996 ENSG00000258429 ENSG00000136522 ENSG00000147162 ENSG00000278550 ENSG00000108342 ENSG00000144228 ENSG00000205730 ENSG00000163661 ENSG00000274538 ENSG00000135480 ENSG00000198740 ENSG00000078596 ENSG00000115884 ENSG00000005206 ENSG00000136960 ENSG00000112210 ENSG00000122254 ENSG00000133110 ENSG00000182329 ENSG00000118785 ENSG00000172602 ENSG00000136160 ENSG00000054803 ENSG00000086544 ENSG00000186832 ENSG00000101421 ENSG00000170477 ENSG00000188807 ENSG00000166794 ENSG00000164414 ENSG00000145147 ENSG00000048462 ENSG00000130649 ENSG00000169744 ENSG00000167371 ENSG00000137563 ENSG00000067334 ENSG00000135914 ENSG00000119681 ENSG00000106331 ENSG00000116918 ENSG00000086205 ENSG00000105664 ENSG00000133812 ENSG00000128342 ENSG00000151914 ENSG00000121039 ENSG00000175793 ENSG00000124766 ENSG00000132185 ENSG00000178919 ENSG00000149311 ENSG00000103227 ENSG00000162733 ENSG00000127533 ENSG00000163827 ENSG00000145819 PMC7226501__F8 Regulatory model of VP4 in antiviral signaling in grass carp ENSG00000183735 ENSG00000172936 ENSG00000276561 PMC8006920__F4 Pathway enrichment of hubs: The common pathway (red rhombus) shared by three protein hubs (yellow rectangle) extracted from the metalloprotein network ENSG00000198793 ENSG00000105656 PMC7022656__F1 Inhibition of Nrf1 N-glycosylation by tunicamycin (TU) in the endoplasmic reticulum (ER)- to-nuclear signaling responses ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000106459 PMC10508215__F1 AKR1C3 Converts Castrate and Post-Abiraterone DHEA-S into Testosterone to Stimulate Growth of Prostate Cancer Cells via 5-Androstene-3B,17Beta-Diol ENSG00000151632 ENSG00000203857 ENSG00000187134 PMC8867758__F4 MicroRNA regulates the toxicological mechanism of four mycotoxins in vivo and in vitro ENSG00000002330 ENSG00000130669 PMC6254932__F6 VHL-HIF-BNIP3 signaling pathway ENSG00000134086 ENSG00000163235 ENSG00000138798 PMC5927447__F10 NF2 signaling pathway plays a pro-apoptotic role in Beta-adrenergic receptor stimulated cardiac myocyte apoptosis ENSG00000186575 PMC5596881__F2 Therapeutic targets in Nrf2-dependent protection against neonatal respiratory distress disease predicted by cDNA microarray analysis and bioinformatics tools ENSG00000174156 ENSG00000102908 ENSG00000163519 ENSG00000213614 ENSG00000068885 ENSG00000124875 ENSG00000205250 ENSG00000176971 ENSG00000124762 ENSG00000138356 ENSG00000101868 ENSG00000065833 ENSG00000150991 ENSG00000148773 ENSG00000163734 ENSG00000164400 ENSG00000087842 ENSG00000137440 ENSG00000165323 ENSG00000139278 ENSG00000253729 ENSG00000130513 ENSG00000166349 ENSG00000101639 ENSG00000151012 ENSG00000140263 ENSG00000168000 ENSG00000109321 ENSG00000198851 ENSG00000095787 ENSG00000173726 ENSG00000144354 ENSG00000115760 ENSG00000104814 ENSG00000146250 ENSG00000170458 ENSG00000015285 ENSG00000171848 ENSG00000164754 ENSG00000271303 ENSG00000172936 ENSG00000154188 ENSG00000136689 PMC5858488__F1 MTOR signaling pathway ENSG00000198793 ENSG00000164327 ENSG00000167965 ENSG00000146648 PMC10377491__F1 Landscape of Small Leucine-Rich Proteoglycan Impact on Cancer Pathogenesis with a Focus on Biglycan and Lumican ENSG00000189403 ENSG00000078098 ENSG00000168610 ENSG00000109670 PMC3128635__F2 Crosstalk and feedback in ERK and PI3K signaling downstream of RAS ENSG00000169047 PMC3128635__F1 RAS signaling to the PI3K pathway ENSG00000002330 ENSG00000169047 ENSG00000198793 ENSG00000164327 PMC4447220__F6 Conceptual model of the effects of 15-LOX-1 on the PPARD–IL-6/STAT3 signaling pathway in relation to colorectal tumorigenesis ENSG00000074181 ENSG00000168610 PMC10341567__F4 Major pathways and interactions regulated by BACE1: (A) Notch signaling pathway, (B) Amyloidogenic pathway, and (C) NFKB pathway ENSG00000148400 PMC10341567__F3 Major pathways and interactions regulated by GSK3B: (A) Wnt/B-catenin pathway and (B)PI3K/Akt/mTor pathway ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC10341567__F6 Major pathways in which ABCA1 plays an important role for cholesterol transport in brains: (A) Reverse cholesterol transport pathway, (B) LXR/RXR pathway, and (C) SREBP2 pathway ENSG00000135218 ENSG00000073060 PMC10341567__F5 Major signaling pathways that regulate SREBP2 activation during cholesterol synthesis: (A) P53 pathway, and (B) Akt pathway PMC8795088__F5 Striatal Chloride Dysregulation and Impaired GABAergic Signaling Due to Cation-Chloride Cotransporter Dysfunction in Huntington’s Disease ENSG00000197386 PMC10341567__F7 TREM2/DAP12 pathway ENSG00000168036 PMC9038119__F1 Targeting metabolic pathways for extension of lifespan and healthspan across multiple species ENSG00000147162 ENSG00000198408 PMC8045214__F9 Association of cyclin-dependent kinase inhibitor 2B antisense RNA 1 gene expression and rs2383207 variant with breast cancer risk and survival ENSG00000198901 ENSG00000084093 ENSG00000167554 ENSG00000197951 ENSG00000275111 ENSG00000102349 ENSG00000136997 ENSG00000178691 ENSG00000179348 ENSG00000102935 ENSG00000102974 ENSG00000106546 PMC11969919__F4 Transcriptome profiles of blastocysts originating from oocytes matured in follicular fluid from preovulatory follicles of greater or lesser maturity ENSG00000134982 ENSG00000101350 ENSG00000137992 ENSG00000008394 ENSG00000168036 ENSG00000152804 ENSG00000168646 ENSG00000109787 ENSG00000118946 PMC9038119__F3 Targeting metabolic pathways for extension of lifespan and healthspan across multiple species ENSG00000105835 ENSG00000278488 ENSG00000158104 ENSG00000183077 PMC9038119__F5 Targeting metabolic pathways for extension of lifespan and healthspan across multiple species ENSG00000128050 ENSG00000156110 ENSG00000198931 ENSG00000158125 PMC10341567__F1 Main pathways involved in cholesterol transport involved in Alzheimer’s Disease ENSG00000142192 ENSG00000036530 PMC8913803__F3 Signaling pathways and targeted therapy for myocardial infarction ENSG00000162711 ENSG00000172936 ENSG00000150455 ENSG00000175104 PMC8913803__F2 Signaling pathways and targeted therapy for myocardial infarction ENSG00000148400 ENSG00000074181 ENSG00000154721 ENSG00000062485 PMC10834963__F8 Proposed signaling mechanism for the effects of amlexanox on LPS-induced neuroinflammation in BV2 microglial cells ENSG00000169245 ENSG00000108691 ENSG00000168610 PMC5272937__F1 The HCV interactions (both direct and indirect) on the hepatocyte insulin signaling pathway ENSG00000124102 ENSG00000008710 ENSG00000169047 ENSG00000198793 PMC5419442__F9 Possible Signaling Pathway that Mediates FSH-Induced Meiotic Resumption of Mouse OocytesAfter binding with its membrane-integrated receptor in cumulus cells, FSH uses PKAII as a downstream mediator after a transient increase of cAMP ENSG00000146648 PMC6887669__F1 Two‐signal model of inflammasome signaling ENSG00000162711 ENSG00000125538 PMC8765442__F2 Heart Failure with Targeted Cancer Therapies: Mechanisms and Cardioprotection ENSG00000122025 PMC6735914__F3 DAXX in cell death ENSG00000177169 ENSG00000132109 ENSG00000137275 ENSG00000064393 ENSG00000033800 ENSG00000167996 ENSG00000171791 ENSG00000168040 ENSG00000127191 ENSG00000140464 ENSG00000285379 ENSG00000026103 PMC8100458__F2 Advances and Insights of APC-Asef Inhibitors for Metastatic Colorectal Cancer Therapy ENSG00000019991 ENSG00000070831 ENSG00000134982 ENSG00000074181 ENSG00000168036 ENSG00000100985 PMC8913803__F5 Signaling pathways and targeted therapy for myocardial infarction ENSG00000115415 ENSG00000168610 PMC8913803__F4 Signaling pathways and targeted therapy for myocardial infarction ENSG00000074181 ENSG00000067900 ENSG00000127948 ENSG00000079999 PMC8913803__F7 Signaling pathways and targeted therapy for myocardial infarction ENSG00000157933 ENSG00000291971 ENSG00000164093 ENSG00000164690 ENSG00000150457 ENSG00000128602 ENSG00000131023 PMC8913803__F6 Signaling pathways and targeted therapy for myocardial infarction ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000155011 ENSG00000168036 PMC5869932__F2 Roles of ZBTB proteins in B-cell development, differentiation, and function ENSG00000178951 ENSG00000126804 ENSG00000112365 ENSG00000173599 ENSG00000137265 ENSG00000196092 ENSG00000171791 ENSG00000011590 ENSG00000168685 PMC3757945__F3 Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair ENSG00000134982 ENSG00000168036 ENSG00000150457 ENSG00000131023 ENSG00000140443 PMC8948957__F2 Combined Targeted and Untargeted Profiling of HeLa Cells Deficient in Purine De Novo Synthesis ENSG00000128050 PMC2661568__F6 Schematic model of sequential hippocampal aging changes ENSG00000057252 ENSG00000189058 PMC4185356__F1 Control of endotoxin tolerance by AhR ENSG00000262635 ENSG00000136869 ENSG00000106546 PMC3904516__F8 LPS-Stimulated Inflammatory Environment Inhibits BMP-2-Induced Osteoblastic Differentiation Through Crosstalk Between TLR4/MyD88/NFKB and BMP/Smad Signaling ENSG00000170365 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000108821 PMC10886830__F7 Toll-like receptor (TLR) signaling pathway with a focus on TLR4 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC6835115__F3 Targeting PKCι-PAK1 in EGFR-mutation positive non-small cell lung cancer ENSG00000167601 ENSG00000114346 ENSG00000291971 ENSG00000149269 ENSG00000163814 ENSG00000168610 ENSG00000146648 PMC6311107__F2 Simplified model of the molecular pathways by which pazopanib and AR42 combine to kill cancer cells ENSG00000094631 ENSG00000149311 ENSG00000177169 ENSG00000002330 ENSG00000144895 ENSG00000198793 ENSG00000196591 ENSG00000100429 ENSG00000163517 PMC6478125__F1 RUNX3 and p53 act independently and in concert to elicit their tumour suppressive function ENSG00000149311 ENSG00000175054 ENSG00000020633 PMC6311107__F4 Simplified model of the molecular pathways by which neratinib and valproate combine to kill cancer cells ENSG00000149311 ENSG00000177169 ENSG00000144895 ENSG00000065361 ENSG00000198793 ENSG00000134853 ENSG00000057663 ENSG00000178568 PMC8634264__F2 Moderate Intensity Aerobic Exercise Potential Favorable Effect Against COVID-19: The Role of Renin-Angiotensin System and Immunomodulatory Effects ENSG00000130234 ENSG00000184012 ENSG00000079999 PMC4773033__F2 Comprehensive picture showing gene expression changes and crosstalk of pathways associated with Igf1 and Pacap rescue of apoptotic CGNs ENSG00000174156 ENSG00000162552 ENSG00000182687 ENSG00000105550 ENSG00000081248 ENSG00000169047 ENSG00000150093 ENSG00000146733 ENSG00000121966 ENSG00000143418 ENSG00000186810 ENSG00000102879 ENSG00000138166 ENSG00000126803 ENSG00000010810 ENSG00000179761 ENSG00000172482 ENSG00000111186 ENSG00000113263 ENSG00000164690 ENSG00000077782 PMC4993794__F1 Tarp protein mediated signaling pathways implicated in chlamydial entry and development ENSG00000291971 ENSG00000115904 ENSG00000160293 PMC3788606__F3 TGFB signaling ENSG00000157933 ENSG00000163914 PMC12066627__F1 Molecular and cellular signaling of intestinal tuft cells in response to infections ENSG00000197943 ENSG00000269404 ENSG00000166090 PMC3306981__F1 Summarized the signaling mechanisms of various matricellular proteins contributing to cancer progression ENSG00000138795 ENSG00000041982 ENSG00000113140 ENSG00000163914 PMC4839364__F1 (T)cell-inflamed and non-(T)cell-inflamed phenotypes ENSG00000169245 ENSG00000138755 PMC4497751__F2 MicroRNA regulation of lymphocyte tolerance and autoimmunity ENSG00000002330 ENSG00000198793 ENSG00000040199 ENSG00000010671 PMC9250769__F1 Pharmacological Aspects of Natural Quercetin in Rheumatoid Arthritis ENSG00000151657 PMC6610456__F1 TRAFs in IL-17 signaling pathway ENSG00000196843 ENSG00000082512 ENSG00000146216 ENSG00000157625 ENSG00000131323 ENSG00000155313 ENSG00000175104 ENSG00000127191 ENSG00000146648 ENSG00000163702 ENSG00000076604 PMC8283906__F3 Neutrophil Extracellular Traps: A New Player in Cancer Metastasis and Therapeutic Target ENSG00000239732 ENSG00000147419 ENSG00000005381 PMC10731584__F7 Simplified de novo sphingolipid biosynthesis pathway ENSG00000103089 ENSG00000119537 ENSG00000148154 PMC6505627__F2 BCR: a promiscuous fusion partner in hematopoietic disorders ENSG00000186716 ENSG00000134853 ENSG00000077782 PMC11273247__F11 Sodium sulphate ameliorates hypercholesterolemia and hepatic insulin resistance in mice fed an HCD ENSG00000160867 ENSG00000167910 ENSG00000169047 PMC4751708__F2 Gene networks ENSG00000004975 ENSG00000140992 ENSG00000005339 ENSG00000187796 ENSG00000132357 ENSG00000178498 ENSG00000121879 ENSG00000090932 ENSG00000111537 ENSG00000168214 ENSG00000205155 ENSG00000196498 ENSG00000133961 ENSG00000114315 ENSG00000100603 PMC8270322__F1 Pros and Cons of the Cannabinoid System in Cancer: Focus on Hematological Malignancies ENSG00000123374 PMC6338329__F7 Mechanisms for human cervical epithelial cells (HCEs)-mediated HIV suppression in macrophage ENSG00000213928 ENSG00000187608 ENSG00000105397 ENSG00000089127 ENSG00000115415 ENSG00000168610 ENSG00000276561 ENSG00000164342 ENSG00000142166 PMC3643422__F1 Illustration showing the overall sex hormone metabolic pathway and subpathways ENSG00000082175 ENSG00000129214 PMC7261174__F10 IKBKE mediated AR signalling ENSG00000263528 ENSG00000136997 ENSG00000150457 PMC4334626__F1 Proposed schematic model showing how the crosstalk between healthy or oxidized/senescent red blood cells (RBCs) and immune cells may exert anti- and proatherogenic effects, respectively ENSG00000164151 PMC3220493__F6 Schematic model in which FGF2 stimulation of osteoblast differentiation is partially through modulation of the Wnt/Beta-catenin pathway ENSG00000128272 ENSG00000281324 ENSG00000162337 ENSG00000169884 ENSG00000168036 PMC5270455__F15 Directional pathway satisfying TIM of Table ENSG00000146648 PMC5270455__F14 Directional pathway satisfying TIM of Table ENSG00000146648 PMC4286365__F1 Biosynthetic and recycling routes in MDCK cells: the new paradigm ENSG00000130164 ENSG00000162896 PMC7355786__F3 Mechanism of the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway PMC7859603__F1 DisGeNET contains a list of diseases associated genes that have been collected based on the presence of genetic overlaps between diseases ENSG00000134460 ENSG00000162711 ENSG00000042832 ENSG00000134982 ENSG00000173039 ENSG00000164399 ENSG00000007908 ENSG00000171791 ENSG00000168610 ENSG00000007171 ENSG00000132170 ENSG00000108691 ENSG00000111537 ENSG00000121068 ENSG00000172216 ENSG00000170458 ENSG00000149968 ENSG00000177606 ENSG00000276051 ENSG00000277263 ENSG00000112115 ENSG00000146648 ENSG00000026103 PMC3121446__F6 P53 activation by NML-MYBBP1A in response to glucose limitation ENSG00000132382 PMC5737867__F5 The involvement of the brain-derived neurotrophic factor (BDNF)-glycogen synthase kinase-3B (GSK-3B)-Beta-catenin pathway in the antidepressant-like effects of Morinda officinalis oligosaccharides (MOs) and resilience to stress ENSG00000172680 ENSG00000168036 PMC7240858__F1 Innate immune checkpoints influencing DC function in the TME ENSG00000198053 ENSG00000104972 ENSG00000272398 ENSG00000189403 ENSG00000184500 PMC9608343__F1 Metabolic features of myeloma cells in the context of bone microenvironment: Implication for the pathophysiology and clinic of myeloma bone disease ENSG00000178860 ENSG00000152266 ENSG00000154342 ENSG00000169884 ENSG00000258429 PMC8126571__F1 Bidirectional microglia–neuron interactions in the healthy or stressed brain ENSG00000125538 ENSG00000184371 ENSG00000189403 PMC86258__F8 Shc/Grb2/Gab2/PI-3K Akt pathway ENSG00000169291 ENSG00000033327 ENSG00000164136 ENSG00000164399 ENSG00000113525 PMC5935908__F8 NRP-1/TNC/Integrin B3/FAK/Akt/NFKB schematic signaling pathway ENSG00000259207 ENSG00000041982 ENSG00000118777 PMC7417304__F4 Emerging roles of Hippo-YAP signaling in the modulation of innate anti-tumor immunity ENSG00000184371 ENSG00000113520 ENSG00000172936 ENSG00000131023 PMC6121402__F1 Mammalian target of rapamycin (mTOR) pathway ENSG00000169047 ENSG00000145979 PMC7417304__F1 Signaling mechanism and regulation of the Hippo pathway in drosophila and mammals ENSG00000114978 ENSG00000131023 PMC3109273__F1 Host cell death pathways targeted by L ENSG00000073578 PMC7417304__F3 Hippo pathway in innate antiviral immunity ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000172936 ENSG00000131323 ENSG00000150457 ENSG00000131023 PMC7417304__F2 Hippo pathway in innate anti-bacterial immunity ENSG00000183735 ENSG00000172936 ENSG00000131323 ENSG00000130159 ENSG00000175104 ENSG00000276561 PMC4012154__F1 Signaling pathways involved in microglial phagocytosis ENSG00000070831 ENSG00000172936 PMC9477794__F2 Targeting epigenetic regulators for inflammation: Mechanisms and intervention therapy ENSG00000162711 ENSG00000125538 ENSG00000173039 ENSG00000172936 PMC8005405__F2 Mechanisms regulating ROS in LSCs ENSG00000214253 PMC3197200__F2 Intracellular signaling pathways regulating growth ENSG00000140443 PMC8587556__F4 Huperzine A and Its Neuroprotective Molecular Signaling in Alzheimer’s Disease ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000185483 ENSG00000168036 PMC3214149__F3 Schematic overview of CagL and CagA-mediated signal transduction pathways involved in H ENSG00000065802 PMC8618071__F7 Fungicidal Activity of Recombinant Javanicin against Cryptococcus neoformans Is Associated with Intracellular Target(s) Involved in Carbohydrate and Energy Metabolic Processes ENSG00000062485 PMC8056183__F2 Cell death pathways and viruses: Role of microRNAs ENSG00000177169 ENSG00000198793 ENSG00000155792 ENSG00000167965 PMC4989102__F6 Network motifs that are coordinately regulated by the miR-17–92 cluster ENSG00000087095 ENSG00000160551 ENSG00000130522 ENSG00000095015 ENSG00000197442 ENSG00000155903 ENSG00000221823 ENSG00000177189 ENSG00000011566 ENSG00000138166 ENSG00000143507 ENSG00000183943 ENSG00000100784 ENSG00000164086 PMC8056183__F1 Indirect effects of viruses on the apoptotic pathway through deregulation of cellular miRNAsmiR-2861 increased the apoptosis of cervical cancer cells through the PI3K/AKT pathway by targeting EGFR ENSG00000002330 ENSG00000102871 ENSG00000291971 ENSG00000171791 ENSG00000168040 ENSG00000127191 PMC6490153__F6 Pathway summary of a host defense mechanism response to bacterial meningitis caused by Streptococcus pneumoniae ENSG00000139687 PMC10340243__F5 The main metabolic pathways of unsaturated fatty acids ENSG00000108839 ENSG00000179477 PMC7364557__F2 Model for tau pathogenesis ENSG00000162711 ENSG00000168329 ENSG00000010810 PMC7364557__F1 Model for ABeta-induced neurotoxicity and glial response in AD ENSG00000142192 ENSG00000135218 ENSG00000116106 ENSG00000010810 ENSG00000136869 ENSG00000036828 ENSG00000274513 ENSG00000133216 ENSG00000171885 PMC2698768__F9 Model of CD28 signaling pathways initiated by the distal and proximal motifs PMC5295004__F8 Proposed model of selected miRNA action on the regulatory T cell pathway ENSG00000163599 ENSG00000020633 ENSG00000049768 PMC3580185__F7 Working model for the role of TAK1 lysine-72 in the negative regulation of TNFAlpha-induced NFKB activation ENSG00000102871 ENSG00000173039 ENSG00000162924 ENSG00000127191 PMC8347056__F3 Isoform-Specific Properties of Orai Homologues in Activation, Downstream Signaling, Physiology and Pathophysiology ENSG00000175938 ENSG00000167323 ENSG00000293604 PMC5490254__F2 WNT and SHH signaling pathways ENSG00000134982 ENSG00000164690 ENSG00000128602 PMC4375971__F1 Obesity genetics in mouse and human: back and forth, and back again ENSG00000178188 ENSG00000166402 ENSG00000112246 ENSG00000115138 ENSG00000124089 ENSG00000166603 ENSG00000168610 ENSG00000135324 PMC5370457__F1 Mechanism of signaling transduction of vascular permeability ENSG00000115648 ENSG00000070831 PMC5646121__F3 Direct and indirect targeting of the B cell receptor signaling pathway ENSG00000177455 ENSG00000095585 ENSG00000007312 ENSG00000186716 ENSG00000198793 ENSG00000197943 ENSG00000010671 PMC6277481__F1 Genetics and molecular pathways for PPGLs Pathways for the New Genes; Placing the New into Perspective ENSG00000135956 ENSG00000136997 ENSG00000120868 ENSG00000167985 PMC8891265__F1 Diet, lipids, and antitumor immunity ENSG00000131473 ENSG00000099194 ENSG00000159335 ENSG00000026103 PMC2978917__F7 Signaling pathway and transcription factors involved in HPR1 gene expression in cancer ENSG00000185591 ENSG00000146648 ENSG00000166211 PMC4259002__F4 Epidermal growth factor receptor pathway ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC10478470__F2 HMGB1 and TLRs signaling pathway ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC6329348__F3 Assessment of in vivo genotoxicity of citrated-coated silver nanoparticles via transcriptomic analysis of rabbit liver tissue ENSG00000123975 ENSG00000292286 ENSG00000084093 ENSG00000171476 ENSG00000130826 ENSG00000110799 ENSG00000165280 ENSG00000087586 ENSG00000197223 ENSG00000076003 ENSG00000187672 ENSG00000070019 ENSG00000079112 ENSG00000167772 ENSG00000164938 ENSG00000183579 ENSG00000256646 ENSG00000101425 PMC8428079__F2 Targeting Beta-cell dedifferentiation and transdifferentiation: opportunities and challenges ENSG00000104856 ENSG00000070831 ENSG00000102871 ENSG00000134853 ENSG00000173039 ENSG00000182759 ENSG00000168040 ENSG00000127191 PMC9621333__F1 Epstein–Barr virus infection, B‐cell dysfunction and other risk factors converge in gut‐associated lymphoid tissue to drive the immunopathogenesis of multiple sclerosis: a hypothesis ENSG00000186716 PMC2801177__F4 Identification of candidate molecular network for miRNAs most highly changed in response to DEP ENSG00000145632 ENSG00000196323 ENSG00000083312 ENSG00000132639 ENSG00000172216 ENSG00000084676 ENSG00000144935 ENSG00000139842 ENSG00000107485 ENSG00000164093 ENSG00000001626 ENSG00000069345 ENSG00000204217 ENSG00000114739 PMC2801177__F3 Subnetworks of select putative DEP-regulated gene transcripts show an enrichment of inflammatory response ENSG00000121207 ENSG00000143248 ENSG00000112972 ENSG00000162493 ENSG00000170677 ENSG00000100852 ENSG00000147526 ENSG00000121966 ENSG00000158125 ENSG00000184500 ENSG00000184602 ENSG00000157500 ENSG00000180957 ENSG00000131142 ENSG00000001626 ENSG00000172380 ENSG00000113070 ENSG00000132463 ENSG00000110108 ENSG00000069329 ENSG00000067900 ENSG00000076053 ENSG00000110693 ENSG00000152034 ENSG00000078053 ENSG00000138166 ENSG00000174233 ENSG00000102245 ENSG00000139842 ENSG00000162545 ENSG00000164093 ENSG00000127588 ENSG00000138760 PMC2242778__F5 Canonical pathway analysis ENSG00000089159 PMC9636380__F1 Activation of RIPK3 by multiple stimuli ENSG00000132109 ENSG00000124256 ENSG00000137275 ENSG00000138032 ENSG00000136869 ENSG00000168404 ENSG00000285379 ENSG00000164342 PMC6085908__F1 Synaptic signaling pathways associated with autism spectrum disorder (ASD) ENSG00000197283 ENSG00000198793 ENSG00000198576 ENSG00000196712 PMC5415789__F6 CeRNA network modulates the PI3K/Akt signaling pathway ENSG00000128272 ENSG00000145623 ENSG00000135446 ENSG00000169047 ENSG00000136997 ENSG00000118515 ENSG00000173039 ENSG00000112715 ENSG00000146648 PMC6468516__F2 Metabolism in tumor cells ENSG00000062485 PMC8221295__F6 Mechanistic insights into the anti-depressant effect of emodin: an integrated systems pharmacology study and experimental validation ENSG00000066468 ENSG00000165841 ENSG00000125538 ENSG00000169032 ENSG00000112715 ENSG00000077782 PMC2822054__F1 How the PI3K-AKT and MEK-ERK pathways regulate apoptosis in EGFR driven cancers ENSG00000065361 ENSG00000136997 ENSG00000146648 PMC4632093__F1 Nodes-and-connections strategy generating an interaction map of signaling molecule network required for the fulvestrant-induced MCF-7 cell apoptosis ENSG00000152495 ENSG00000291971 ENSG00000140795 ENSG00000050748 ENSG00000067900 ENSG00000143933 ENSG00000168610 ENSG00000115290 ENSG00000100290 ENSG00000128272 ENSG00000127533 ENSG00000067606 ENSG00000076641 ENSG00000178568 ENSG00000177425 PMC8759533__F1 ALK-positive histiocytosis: a new clinicopathologic spectrum highlighting neurologic involvement and responses to ALK inhibition ENSG00000110395 ENSG00000198793 ENSG00000179295 PMC4252654__F1 MANNOSE METABOLISM: MORE THAN MEETS THE EYE ENSG00000000419 ENSG00000173540 ENSG00000129255 ENSG00000136908 PMC8707026__F1 Molecular Rationale of Insect-Microbes Symbiosis—From Insect Behaviour to Mechanism ENSG00000131323 PMC6300778__F8 JAK2/STAT3 mediated protection of APN against OGD ENSG00000105656 ENSG00000168610 PMC11878481__F1 Autophagy by mTORC1 and AMPK ENSG00000177169 ENSG00000144848 ENSG00000112561 ENSG00000145782 ENSG00000057663 PMC8185197__F1 Hereditary Leiomyomatosis and Renal Cell Cancer: Recent Insights Into Mechanisms and Systemic Treatment ENSG00000112715 ENSG00000076555 ENSG00000110911 PMC9179253__F2 New Therapeutic Strategies for Adult Acute Myeloid Leukemia ENSG00000122025 ENSG00000198793 ENSG00000077782 PMC5242532__F1 Whole Exome Sequencing of Growing and Non-Growing Cutaneous Neurofibromas from a Single Patient with Neurofibromatosis Type 1 ENSG00000129474 ENSG00000134376 ENSG00000148498 ENSG00000126016 ENSG00000143514 ENSG00000026508 ENSG00000150457 ENSG00000131023 ENSG00000169435 PMC3673784__F1 Tankyrase and the canonical Wnt pathway protect lung cancer cells from EGFR inhibition ENSG00000156076 ENSG00000089685 ENSG00000147869 ENSG00000107854 ENSG00000177606 ENSG00000104290 ENSG00000101266 ENSG00000134245 ENSG00000161202 ENSG00000196628 ENSG00000173273 PMC7012784__F2 Anti-tumourigenic JNK signalling ENSG00000185008 PMC4465694__F8 Rapamycin Enhances the Anti-Cancer Effect of Dasatinib by Suppressing Src/PI3K/mTOR Pathway in NSCLC Cells ENSG00000291971 ENSG00000150907 ENSG00000198793 PMC9263135__F9 Bioinformatics-Driven Identification of p62 as A Crucial Oncogene in Liver Cancer ENSG00000149311 ENSG00000105664 ENSG00000184675 ENSG00000112242 ENSG00000116044 ENSG00000163558 ENSG00000067606 ENSG00000154124 ENSG00000079999 ENSG00000106829 ENSG00000109670 PMC7012784__F5 Upstream regulation of JNK signalling ENSG00000162772 ENSG00000175104 ENSG00000076604 PMC4059866__F4 Gene network generated by Ingenuity Pathway Analysis of 5 genes identified to be predicted targets of miRNAs associated with in vitro cisplatin resistance (fold change > 2, P < 0.05) in the current study ENSG00000078900 ENSG00000132466 ENSG00000116030 PMC5302293__F1 Cell-cycle and DNA repair ENSG00000132906 ENSG00000175793 ENSG00000116717 ENSG00000164305 ENSG00000124762 ENSG00000079246 ENSG00000115415 ENSG00000089685 ENSG00000135446 ENSG00000132646 ENSG00000177606 ENSG00000123374 ENSG00000129152 ENSG00000105810 ENSG00000120868 ENSG00000139687 ENSG00000175305 PMC4721605__F2 Key signaling pathways that regulate activity-dependent translation initiation in neurons ENSG00000128272 ENSG00000144895 PMC2726720__F3 Interplay of TGFB, Wnt/Beta-catenin, Hedgehog, and Notch in stem cell differentiation and tumorigenesis ENSG00000135446 PMC7193059__F1 Neurotoxicity of local anesthetics in dentistry ENSG00000002330 ENSG00000168040 PMC12218202__F6 Chlorophyll synthesis and degradation of tomato leaves in WT and slprr1 lines under SD or LD conditions ENSG00000144410 ENSG00000126088 ENSG00000170430 ENSG00000188690 ENSG00000127948 PMC7604390__F1 Model showing intracellular lipid metabolism and AA metabolism in ovarian cancer ENSG00000131473 ENSG00000135218 ENSG00000130164 ENSG00000169710 ENSG00000198670 ENSG00000079432 PMC12020288__F1 Mechanism diagram of RBPs in HCC ENSG00000176624 ENSG00000102317 ENSG00000132463 ENSG00000171863 ENSG00000168610 ENSG00000165795 ENSG00000136231 ENSG00000107581 ENSG00000115946 ENSG00000011304 ENSG00000115457 ENSG00000149658 ENSG00000185298 ENSG00000123352 ENSG00000163577 ENSG00000101210 ENSG00000135097 PMC7168513__F4 DENV‐mediated activation of the cytosolic DNA‐sensing pathway in DCs ENSG00000183735 ENSG00000164430 PMC12020288__F3 RBPs as potential therapeutic targets for HCC ENSG00000100811 ENSG00000115457 ENSG00000149658 ENSG00000281406 ENSG00000132463 ENSG00000139546 ENSG00000184697 ENSG00000178498 ENSG00000132819 ENSG00000147274 PMC3131055__F1 Wolbachia-induced responses of specific cell types ENSG00000081041 ENSG00000239732 ENSG00000170458 ENSG00000163739 ENSG00000125538 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC7168513__F1 Cytosolic DNA‐sensing immune response via cGAS/STING ENSG00000183735 ENSG00000164430 PMC3870290__F4 Potential mechanism of AICD-mediated gene regulation ENSG00000142192 ENSG00000184634 ENSG00000119912 PMC5795380__F1 Protein subnetworks of Ras (the query protein) with Raf and ERK1/2 ENSG00000157764 ENSG00000115904 ENSG00000169032 ENSG00000108061 PMC3870290__F1 Proteolytic processing of the amyloid precursor protein (APP) and Notch ENSG00000142192 ENSG00000119912 PMC10908104__F2 ALS disease pathological signaling pathway ENSG00000147894 PMC5715491__F7 Pathways involved in apoptotic and EMT effect by genistein in HT-29 cells ENSG00000122691 ENSG00000170558 PMC10855445__F3 Interaction between ALR, NLR, and cGLR (cGAS/STING signaling pathway) ENSG00000162711 ENSG00000164430 ENSG00000163568 ENSG00000160703 ENSG00000143258 PMC4049863__F3 Rho-GTPase signaling in leukocyte extravasation PMC5332883__F1 For PD-L1 modulation in HNSCC ENSG00000124102 ENSG00000115415 ENSG00000005882 ENSG00000168610 ENSG00000146648 PMC4786284__F6 Annexin a2 Promotes Development in Arthritis through Neovascularization by Amplification Hedgehog Pathway ENSG00000164690 ENSG00000139549 PMC9185718__F5 An effective nano drug delivery and combination therapy for the treatment of Tuberculosis ENSG00000123999 ENSG00000172936 ENSG00000168040 ENSG00000164305 ENSG00000184216 PMC7613405__F4 Notch signaling pathway and the processes of lateral inhibition and induction ENSG00000148400 ENSG00000074181 PMC3673714__F2 miR221/222 in Cancer: Their Role in Tumor Progression and Response to Therapy ENSG00000100234 ENSG00000168036 PMC6826985__F7 Gene activities in the TGF beta signaling pathway ENSG00000137834 ENSG00000111537 ENSG00000095739 ENSG00000113558 ENSG00000136997 ENSG00000156574 ENSG00000134363 ENSG00000164093 PMC6826985__F6 Gene activities in the calcium signaling pathway ENSG00000182533 ENSG00000156026 ENSG00000186716 ENSG00000171388 PMC1869626__F2 Pathway analysis was performed using PathwayStudio software by importing three of the 32–up-regulated genes in our list ENSG00000099194 ENSG00000070669 ENSG00000106546 PMC7358455__F9 Schematic illustration showing the mechanism of melatonin(Mel)sensitises shikonin(SHK)-induced cancer cell death ENSG00000065833 ENSG00000142082 PMC6826985__F5 Gene activities in the cytokine-cytokine receptor interaction pathway ENSG00000157404 ENSG00000139269 ENSG00000111321 ENSG00000187266 ENSG00000112715 ENSG00000121807 ENSG00000100385 ENSG00000135960 ENSG00000117400 ENSG00000175189 ENSG00000128052 ENSG00000147896 ENSG00000113520 ENSG00000185591 ENSG00000037280 ENSG00000128342 ENSG00000026103 ENSG00000291368 ENSG00000104899 ENSG00000099985 ENSG00000242689 ENSG00000137070 ENSG00000108342 ENSG00000157368 ENSG00000226275 ENSG00000108691 ENSG00000069482 ENSG00000016402 PMC3961361__F8 MAVS-MKK7-JNK2 Defines a Novel Apoptotic Signaling Pathway during Viral Infection ENSG00000088888 ENSG00000102871 ENSG00000131323 ENSG00000083799 ENSG00000175104 PMC4209417__F2 Insulin-like growth factor-I receptor signaling pathway ENSG00000002330 ENSG00000132646 ENSG00000169047 ENSG00000198793 PMC9313262__F5 High-Throughput Proteomic Analysis of Human Dermal Fibroblast Response to Different Blood Derivatives: Autologous Topical Serum Derived from Plasma Rich in Growth Factors (PRGF) versus Leukocyte- and Platelet-Rich Plasma (L-PRP) ENSG00000146376 ENSG00000041982 ENSG00000011422 ENSG00000110799 ENSG00000197632 ENSG00000087586 ENSG00000143933 ENSG00000164171 ENSG00000138160 ENSG00000111641 ENSG00000112742 PMC9313262__F4 High-Throughput Proteomic Analysis of Human Dermal Fibroblast Response to Different Blood Derivatives: Autologous Topical Serum Derived from Plasma Rich in Growth Factors (PRGF) versus Leukocyte- and Platelet-Rich Plasma (L-PRP) ENSG00000091986 ENSG00000030582 ENSG00000112972 ENSG00000011422 ENSG00000181163 ENSG00000115415 ENSG00000078747 ENSG00000075420 ENSG00000164171 ENSG00000149480 ENSG00000140416 PMC6923859__F3 Wingless (WNT)-signaling pathway as a central way to Braford anti-tick resistant (R) response ENSG00000019991 ENSG00000154764 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000135111 ENSG00000137845 ENSG00000118971 ENSG00000104332 ENSG00000112715 ENSG00000129219 ENSG00000169291 ENSG00000106571 ENSG00000011422 ENSG00000136997 ENSG00000165879 ENSG00000185269 ENSG00000155760 ENSG00000137673 ENSG00000167346 ENSG00000277641 ENSG00000145604 ENSG00000108691 ENSG00000026508 ENSG00000205927 ENSG00000146070 ENSG00000188763 ENSG00000161202 ENSG00000168646 ENSG00000146648 ENSG00000123268 PMC9313262__F3 High-Throughput Proteomic Analysis of Human Dermal Fibroblast Response to Different Blood Derivatives: Autologous Topical Serum Derived from Plasma Rich in Growth Factors (PRGF) versus Leukocyte- and Platelet-Rich Plasma (L-PRP) ENSG00000091986 ENSG00000030582 ENSG00000011422 ENSG00000181163 ENSG00000134057 ENSG00000165458 ENSG00000087586 ENSG00000143933 ENSG00000108821 PMC9428246__F2 Propofol on macrophage activation and function in diseases ENSG00000162711 ENSG00000115415 ENSG00000291971 ENSG00000189403 ENSG00000136869 PMC4245043__F1 Model of the Fanconi functional pathway and protein components ENSG00000175054 ENSG00000276787 ENSG00000078098 ENSG00000139618 PMC3478095__F2 Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease ENSG00000100697 ENSG00000092847 ENSG00000128191 ENSG00000113360 ENSG00000134698 ENSG00000123908 PMC9428246__F4 Propofol on macrophage activation and function in diseases ENSG00000169245 ENSG00000260314 ENSG00000136869 ENSG00000118520 ENSG00000168610 PMC9313262__F6 High-Throughput Proteomic Analysis of Human Dermal Fibroblast Response to Different Blood Derivatives: Autologous Topical Serum Derived from Plasma Rich in Growth Factors (PRGF) versus Leukocyte- and Platelet-Rich Plasma (L-PRP) ENSG00000171855 ENSG00000224320 ENSG00000112972 ENSG00000115415 ENSG00000111799 ENSG00000197632 ENSG00000128335 ENSG00000163661 PMC4290619__F8 Signaling pathway of coagulation cascade for schizophrenia ENSG00000126218 ENSG00000101981 ENSG00000117525 ENSG00000160180 ENSG00000057593 ENSG00000198734 ENSG00000088926 ENSG00000185010 ENSG00000149295 PMC10311035__F3 Wnt signaling: Essential roles in osteoblast differentiation, bone metabolism and therapeutic implications for bone and skeletal disorders ENSG00000134982 ENSG00000168036 ENSG00000167965 PMC7378668__F7 Genes and processes involved in the 04662.B cell receptor signalling pathway ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000105656 ENSG00000110651 ENSG00000010671 PMC6614345__F3 Differentially expressed miRNAs in thyroid cancer tissues modulating the TGFB pathway ENSG00000105329 PMC8689584__F2 The major DNA damage repair pathways impaired in HPV-positive cancers ENSG00000175054 ENSG00000163961 ENSG00000051180 ENSG00000153827 ENSG00000139687 ENSG00000139618 PMC10311035__F2 Wnt signaling: Essential roles in osteoblast differentiation, bone metabolism and therapeutic implications for bone and skeletal disorders ENSG00000170365 ENSG00000186575 ENSG00000128917 ENSG00000134982 ENSG00000167941 ENSG00000168036 ENSG00000150457 ENSG00000104332 ENSG00000128602 ENSG00000131023 ENSG00000090932 PMC11188434__F0 GUP can effectively inhibit the activation of cGAS-STING pathway induced by multiple stimuli and reduce the expression of type I interferon and pro-inflammatory cytokines ENSG00000164430 PMC7378668__F6 Genes and processes involved in the 04660.T cell receptor signalling pathway ENSG00000291603 ENSG00000110395 ENSG00000213658 ENSG00000117091 ENSG00000010810 ENSG00000135446 ENSG00000163599 ENSG00000113263 PMC7378668__F5 Genes and processes involved in the 04145.Phagosome pathway ENSG00000003056 ENSG00000102189 ENSG00000170458 ENSG00000168818 ENSG00000136869 ENSG00000005381 ENSG00000274145 PMC6953314__F3 Intracellular signaling pathways of CAP, SNS, and HPA axis for anti-inflammatory responses ENSG00000105550 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000168610 PMC9607206__F6 Review of Omics Studies on Arboviruses: Alphavirus, Orthobunyavirus and Phlebovirus ENSG00000088888 ENSG00000140968 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC8227550__F3 RNA Helicase DDX3: A Double-Edged Sword for Viral Replication and Immune Signaling ENSG00000162711 ENSG00000183735 ENSG00000088888 ENSG00000276561 PMC6370374__F6 Molecular mechanism underlying LINC01133 regulated pancreatic cancer progression ENSG00000168036 ENSG00000125084 PMC6126176__F4 miRNA-risk genes-pathways regulation network ENSG00000177570 ENSG00000186272 ENSG00000172469 ENSG00000185658 ENSG00000132485 ENSG00000184292 ENSG00000038002 ENSG00000166822 ENSG00000185010 ENSG00000118508 ENSG00000135824 ENSG00000197134 ENSG00000164066 ENSG00000138032 ENSG00000084073 ENSG00000145782 ENSG00000180730 ENSG00000163884 ENSG00000026103 ENSG00000143995 ENSG00000148411 ENSG00000169554 ENSG00000134940 ENSG00000111530 ENSG00000197905 ENSG00000083312 ENSG00000165678 ENSG00000150433 ENSG00000106261 ENSG00000109163 ENSG00000260314 ENSG00000226275 ENSG00000080371 ENSG00000182827 ENSG00000103460 ENSG00000280663 ENSG00000203943 ENSG00000292035 ENSG00000183530 ENSG00000256646 ENSG00000050426 ENSG00000178662 ENSG00000102974 PMC6126176__F6 miRNA-core gene-risk signaling pathway regulation network ENSG00000117020 ENSG00000181104 ENSG00000135932 ENSG00000120868 ENSG00000277401 PMC5696061__F2 Rethinking HSF1 in stress, development and organismal health ENSG00000284774 ENSG00000198793 ENSG00000096717 ENSG00000109670 PMC5595345__F8 Deregulation of KSHV latency conformation by ER-stress and caspase-dependent RAD21-cleavage ENSG00000108055 ENSG00000164754 ENSG00000102974 PMC6614345__F2 Differentially expressed miRNAs in thyroid cancer tissues modulating the PI3K pathway ENSG00000198793 ENSG00000113532 PMC6224293__F1 Pathways involved in the synthesis of the main glycerolipids present in Arabidopsis mitochondrial membranes ENSG00000173599 ENSG00000184207 PMC9016027__F1 Synaptic or Non-synaptic? Different Intercellular Interactions with Retinal Ganglion Cells in Optic Nerve Regeneration ENSG00000169783 ENSG00000291720 ENSG00000075213 PMC6614345__F1 Differentially expressed miRNAs in thyroid cancer tissues modulating the MAPK pathway ENSG00000157764 ENSG00000115904 ENSG00000146648 PMC9513225__F1 Implication of non-coding RNA-mediated ROCK1 regulation in various diseases ENSG00000087245 ENSG00000170558 ENSG00000132646 ENSG00000168610 PMC11958968__F11 DSF against renal fibrosis via inhibition of PIK3/Akt/mTOR signaling pathway ENSG00000170558 ENSG00000198793 PMC10311035__F1 Wnt signaling: Essential roles in osteoblast differentiation, bone metabolism and therapeutic implications for bone and skeletal disorders ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11513202__F2 Relationships between DNA methylation and hepatocellular carcinoma (HCC) proliferation, apoptosis and angiogenesis ENSG00000135446 ENSG00000064012 PMC5979509__F4 VEGFR2 signal transduction and trafficking pathways mediated by VEGF-A ENSG00000107338 ENSG00000002330 ENSG00000291971 PMC2742684__F1 Key signaling pathways between amino acids, inflammatory cytokines, and tumor-specific factors gr1Amino acids stimulate muscle protein synthesis through the mTOR pathway ENSG00000198793 ENSG00000129152 PMC5686903__F2 Over-expressed genes of Basal-like samples in p53 signaling pathway ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000136997 ENSG00000123374 ENSG00000112378 ENSG00000196470 ENSG00000164305 ENSG00000026103 PMC6687952__F7 Pathway convergence of proteins encoded by both ASD DMRs ENSG00000002330 ENSG00000198793 ENSG00000130649 ENSG00000140443 PMC8573085__F1 Lipotoxic Proximal Tubular Injury: A Primary Event in Diabetic Kidney Disease ENSG00000135218 ENSG00000026103 PMC8258105__F1 Severe Clinical Worsening in COVID-19 and Potential Mechanisms of Immune-Enhanced Disease ENSG00000169245 ENSG00000108691 ENSG00000239732 ENSG00000187796 ENSG00000130234 ENSG00000184012 ENSG00000085265 ENSG00000277943 PMC9278015__F4 Significance of interferon signaling based on mRNA-microRNA integration and plasma protein analyses in critically ill COVID-19 patients ENSG00000197296 PMC8961531__F3 Neurobiological and Pharmacological Perspectives of D3 Receptors in Parkinson’s Disease ENSG00000198793 ENSG00000198576 ENSG00000101327 PMC11945619__F6 Principal component analysis (PCA) of growth and development indices and related genes in the liver tissue of Rana zhenhaiensis tadpoles after exposure to polypropylene (PP) and polystyrene (PS) ENSG00000131473 ENSG00000029364 ENSG00000104365 ENSG00000262785 ENSG00000166130 ENSG00000073578 ENSG00000204463 ENSG00000117118 ENSG00000133835 ENSG00000155792 ENSG00000087085 ENSG00000105647 ENSG00000076555 ENSG00000073756 ENSG00000164305 ENSG00000062282 ENSG00000167107 ENSG00000103490 ENSG00000167468 ENSG00000073734 ENSG00000140299 ENSG00000184083 PMC11551650__F3 MET oncogenic activation ENSG00000047410 ENSG00000019991 ENSG00000110395 PMC11551650__F6 C-MET pathway relays downstream signals to activate multiple oncogenic events to promote cell proliferation, migration, protein synthesis, and antiapoptosis ENSG00000019991 ENSG00000002330 ENSG00000198793 ENSG00000168610 PMC4750502__F5 Retinoic Acid-Related Orphan Receptors (RORs): Regulatory Functions in Immunity, Development, Circadian Rhythm, and Metabolism ENSG00000170271 ENSG00000132196 ENSG00000084676 ENSG00000001630 ENSG00000116133 ENSG00000172893 ENSG00000149809 ENSG00000109929 ENSG00000180432 ENSG00000104549 ENSG00000117707 PMC11551650__F4 Hepatocyte growth factor/c-Met axis activates the Hedgehog pathway through downstream signaling ENSG00000019991 ENSG00000106571 ENSG00000164161 ENSG00000166813 ENSG00000198793 ENSG00000128602 ENSG00000168610 PMC4387238__F2 Signals for the lysosome: a control center for cellular clearance and energy metabolism ENSG00000182511 ENSG00000155792 ENSG00000112561 ENSG00000167965 PMC11513202__F7 Pivotal role of DNA methyltransferase in DNA methylation and HCC progression ENSG00000068028 ENSG00000019991 ENSG00000143355 ENSG00000138769 ENSG00000285109 ENSG00000088305 ENSG00000198793 ENSG00000141052 PMC11513202__F4 Relationships between DNA methylation and sorafenib resistance in HCC ENSG00000186575 ENSG00000140505 ENSG00000196591 ENSG00000133422 ENSG00000168610 ENSG00000163517 PMC11513202__F3 Relationships between DNA methylation and adhesion, invasion and metastasis of HCC ENSG00000100234 ENSG00000129910 ENSG00000135638 ENSG00000149968 ENSG00000146648 ENSG00000122194 PMC12113536__F1 Aberrant pathways induced by SMARCB1 deficiency and corresponding therapeutic targets ENSG00000151376 ENSG00000135446 ENSG00000198793 ENSG00000136997 ENSG00000113161 ENSG00000087586 ENSG00000105810 PMC7464394__F3 Glutamatergic synapse pathway and expression levels of sea lice exposed to three drugs ENSG00000115419 ENSG00000102977 PMC9561277__F8 APE1 assembles biomolecular condensates to promote the ATR–Chk1 DNA damage response in nucleolus ENSG00000175054 ENSG00000164053 ENSG00000143971 ENSG00000138385 PMC12206236__F1 Defining quality of cancer is cell cycle dysregulation, which results in uncontrolled cell growth and tumor formation ENSG00000135446 ENSG00000123374 ENSG00000105810 PMC3943797__F1 Coagulation, Protease Activated Receptors and Viral Myocarditis ENSG00000164342 PMC6923859__F4 Regulation of immune response as the most relevant pathway in the infested susceptible (S) skin ENSG00000196136 ENSG00000130208 ENSG00000108691 ENSG00000099985 ENSG00000105397 ENSG00000128342 ENSG00000168610 PMC8882872__F3 Aryl Hydrocarbon Receptor Mechanisms Affecting Chronic Kidney Disease ENSG00000105835 ENSG00000130234 ENSG00000106546 PMC3141633__F3 Genes identified in the TGF beta pathway ENSG00000111537 ENSG00000134363 ENSG00000111816 PMC8410789__F8 Working model of Alpha-KG-induced pyroptosis ENSG00000064012 ENSG00000147697 PMC5073228__F2 Integrating Candida albicans metabolism with biofilm heterogeneity by transcriptome mapping ENSG00000123505 ENSG00000146701 PMC5500651__F5 Schematic illustration for signaling pathways of skeletal muscle growth regulated by let-7b ENSG00000112964 ENSG00000136231 PMC6198234__F5 Proposed mechanisms by which PKM2‐mTORC1 regulatory pathways contribute to resistance in RCC cells ENSG00000198793 ENSG00000164327 PMC2928803__F3 Gene Expression Model for the Preferential Galactose Uptake in Yeast Cells ENSG00000069482 ENSG00000173599 ENSG00000174611 PMC12113536__F2 Summary of the role of SMARCB1 deficiency as a driver of the hallmarks of cancer in RTs ENSG00000169245 ENSG00000135077 ENSG00000197992 ENSG00000180644 ENSG00000146648 PMC7549391__F2 Metabolic Messengers: ceramides ENSG00000139624 ENSG00000223802 ENSG00000172292 ENSG00000135218 ENSG00000168958 ENSG00000154227 ENSG00000159346 ENSG00000285070 ENSG00000119537 ENSG00000143418 PMC6148804__F1 Pictorial representation of un-inhibited Avian avulavirus 1 (APMV-1)-induced type I interferon (IFN) response in waterfowl cells ENSG00000213928 ENSG00000088888 ENSG00000105397 PMC5433957__F2 Mechanisms of GPC3 in acute lung injury ENSG00000168036 PMC5433957__F1 Positive and negative effects of GPC3 on its two main signaling pathways ENSG00000106571 ENSG00000115415 ENSG00000166813 ENSG00000177606 ENSG00000168036 PMC5362412__F9 Probing the prostate tumour microenvironment I: impact of glucose deprivation on a cell model of prostate cancer progression ENSG00000100412 ENSG00000105953 PMC9405053__F2 Celastrol: A Promising Agent Fighting against Cardiovascular Diseases ENSG00000168036 PMC9405053__F1 Celastrol: A Promising Agent Fighting against Cardiovascular Diseases ENSG00000162711 ENSG00000284774 ENSG00000069482 ENSG00000164342 PMC6172959__F7 Poxviruses evade cytosolic sensing through disruption of an mTORC1-mTORC2 regulatory circuit ENSG00000183735 ENSG00000164430 ENSG00000164327 PMC2566927__F2 Essence of retrograde signaling in model organisms ENSG00000127837 ENSG00000011143 ENSG00000123374 PMC6728679__F5 Sketch map of the Wnt5a/Ror2 signaling pathway in bone marrow stromal cells (BMSCs) that derives osteoclast precursor migration and differentiation ENSG00000107562 ENSG00000169071 ENSG00000121966 PMC6307990__F7 The proposed model is a graphical representation of the mechanism of interaction of IDO1 and IL6/STAT3/PD-L1 in EMT regulation in bladder tumor cells ENSG00000168610 PMC6669485__F9 Summary diagram of signaling pathway of this study ENSG00000175054 ENSG00000079999 PMC2234434__F3 Genes involved in apoptotic pathways were altered in type II cells isolated from Stat3Δ/Δ mice ENSG00000274619 ENSG00000047410 ENSG00000185652 ENSG00000142192 ENSG00000136457 ENSG00000002330 ENSG00000158169 PMC7084654__F6 Hypothetical alterations of the metabolic pathways for ATP production in low-oxygen stress response PMC4160991__F1 Schematic diagrams of DA dynamics and signaling in (A) Drosophila cuticle, (B) Drosophila brain, and (C) mammalian brain PMC7248557__F1 TLR4 Signaling pathway ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC154144__F2 Canonic Wnt signaling pathway molecules can induce a similar phenotype ENSG00000134982 ENSG00000169884 ENSG00000168036 PMC6026738__F7 Hypothesis model ENSG00000111321 PMC9380290__F1 Mechanisms of quercetin in cancer prevention: focus on cellular and molecular targets ENSG00000149311 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000171791 PMC12138372__F2 Cellular mechanisms of hormones and their effect on bone maintenance ENSG00000167941 ENSG00000162551 ENSG00000171791 ENSG00000131196 PMC4954455__F6 Working model of the molecular mechanisms of HDACi (e.g., abexinostat) on human skeletal (mesenchymal) stem cell differentiation into adipocytes and osteoblasts ENSG00000178860 ENSG00000245848 ENSG00000162551 ENSG00000168036 ENSG00000162692 ENSG00000108821 ENSG00000163884 PMC5341237__F1 Diagram showing key components of the IL‐6 signal transduction pathway that could account for lipogenic gene expression in hepatocytes ENSG00000168610 ENSG00000026103 PMC6027159__F7 TNF-R1 signaling pathway ENSG00000078747 ENSG00000102871 ENSG00000157625 ENSG00000083799 ENSG00000154124 ENSG00000127191 PMC8605459__F1 Pharmacological blockage of the AHR-CYP1A1 axis: a call for in vivo evidence ENSG00000140505 ENSG00000106546 PMC6027159__F9 Nod1/2 signaling pathway ENSG00000167207 ENSG00000157625 PMC3488630__F2 Proposed model of HER2/3 signaling in epithelial cells ENSG00000125538 PMC6027159__F8 IL-1BR1 signaling pathway ENSG00000125538 ENSG00000172936 ENSG00000157625 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC8016646__F2 Promotion, composition and intracellular activation of the VEGF‐VEGFR signalling pathway ENSG00000107338 ENSG00000165197 ENSG00000002330 ENSG00000291971 ENSG00000010810 ENSG00000198793 ENSG00000112715 ENSG00000150630 PMC8538279__F5 Microbiomics in Collusion with the Nervous System in Carcinogenesis: Diagnosis, Pathogenesis and Treatment ENSG00000168610 PMC8016646__F1 FGF‐FGFR signalling pathway ENSG00000198793 PMC12106324__F5 Canonical TGFB signaling via Smad signaling pathway ENSG00000137834 ENSG00000198742 PMC4382841__F5 Proposed model of novel roles of AQP3 and AQP5 in tumor biology ENSG00000291971 ENSG00000198793 ENSG00000146648 PMC4382841__F4 Proposed model of novel role of AQP1 in tumor biology ENSG00000146648 PMC2682028__F9 Changes in metabolism in Prx1-Cre; PORlox/lox limb bud cells and levels of cholesterol ENSG00000131473 ENSG00000160752 ENSG00000120437 ENSG00000167508 PMC3881294__F2 Regulating intestinal function to reduce atherogenic lipoproteins ENSG00000131446 ENSG00000168282 ENSG00000173599 ENSG00000285482 ENSG00000198670 ENSG00000128268 ENSG00000062282 PMC9774615__F1 Predicting and Understanding the Pathology of Single Nucleotide Variants in Human COQ Genes ENSG00000132423 ENSG00000115520 ENSG00000167113 ENSG00000119723 ENSG00000110871 ENSG00000163050 ENSG00000088682 ENSG00000197429 ENSG00000267673 ENSG00000161513 ENSG00000148459 ENSG00000137714 ENSG00000173085 ENSG00000135469 ENSG00000167186 PMC2248159__F2 A part of the yeast cell cycle pathway available from KEGG [26] ENSG00000104499 ENSG00000261832 ENSG00000094804 ENSG00000128656 ENSG00000197601 ENSG00000117399 PMC3010754__F2 Effect of Host Genetic Variation on the Pharmacokinetics and Clinical Response of Non-nucleoside Reverse Transcriptase Inhibitors ENSG00000197408 PMC12095689__F4 Cotadutide enhances hepatic insulin-stimulated signaling pathways in DIO mice ENSG00000155506 ENSG00000171105 ENSG00000169047 ENSG00000111713 ENSG00000155792 ENSG00000167965 ENSG00000100504 ENSG00000219607 PMC7937695__F1 Three kinds of inflammasome pathways associated with pyroptosis ENSG00000278718 ENSG00000168040 PMC9423707__F2 Anoikis resistance in diffuse glioma: The potential therapeutic targets in the future ENSG00000002330 ENSG00000115457 ENSG00000168036 ENSG00000150457 ENSG00000168610 ENSG00000146648 PMC5260888__F7 Role of RIPK1 in ConA hepatitis model ENSG00000137275 ENSG00000102871 ENSG00000127191 PMC7937695__F2 Relevance of the Pyroptosis-Related Inflammasome Pathway in the Pathogenesis of Diabetic Kidney Disease ENSG00000278718 ENSG00000136869 ENSG00000265972 ENSG00000096717 PMC4112623__F2 Cancer related pathways and processes that input into the Hippo pathway ENSG00000186575 ENSG00000198793 ENSG00000164690 ENSG00000131023 PMC4112623__F1 The core Hippo signaling pathway in Drosophila and humans ENSG00000186575 ENSG00000197905 ENSG00000114978 ENSG00000007866 ENSG00000150457 ENSG00000131023 ENSG00000074219 PMC5659038__F5 Relationship between lipids and hedgehog signaling ENSG00000143147 ENSG00000110931 ENSG00000164690 ENSG00000128602 PMC9598289__F13 Design, Synthesis and Evaluation of Novel 1,4-Disubstituted Piperazine-2,5-dione Derivatives as Antioxidants against H2O2-Induced Oxidative Injury via the IL-6/Nrf2 Loop Pathway ENSG00000178573 ENSG00000010810 ENSG00000198793 ENSG00000168610 ENSG00000079999 PMC2405801__F2 Description of possible involved signalling pathways ENSG00000070831 ENSG00000138798 ENSG00000146648 PMC6008986__F1 Kynurenic acid (KA) is the product of kynurenine pathway, the central metabolite of the tryptophan metabolism ENSG00000137944 ENSG00000054277 PMC8013977__F6 IL-15–PI3K–AKT-mTOR signaling for NK cell development ENSG00000150907 ENSG00000107485 PMC8013977__F5 IL-15-JAK-STAT5 signaling for NK cell development ENSG00000120833 ENSG00000112715 ENSG00000105639 PMC7248557__F4 Alteration of TLR4 signaling in pregnancy disorders ENSG00000172936 ENSG00000136869 ENSG00000131323 PMC10897999__F1 Roles of circRNAs involving interaction with RBPs or other proteins in GC ENSG00000104814 ENSG00000148400 ENSG00000288174 ENSG00000026508 ENSG00000243056 ENSG00000103257 ENSG00000123908 ENSG00000136231 PMC6970631__F1 Key CSC signalling pathways Notch, Wnt, and Hedgehog ENSG00000128917 ENSG00000134982 ENSG00000168036 ENSG00000090932 PMC10897999__F3 CircRNAs work as translational templates to contribute to the proliferation and progression of GC ENSG00000143799 ENSG00000100387 ENSG00000134982 ENSG00000198793 PMC6970631__F3 Key CSC signalling pathways TGFB, JAK/STAT3, and NfKB ENSG00000156110 ENSG00000196839 ENSG00000168610 PMC6923785__F1 Mechanisms of resistance to PI3K inhibitors in estrogen receptor (ER)-positive breast cancer and current and future drug combination strategies involving PI3K inhibitors ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000146648 PMC3980897__F1 Dual-view setup of the enRoute visualization technique ENSG00000167941 ENSG00000146648 PMC3285457__F6 Smad7 is Inactivated through a Direct Physical Interaction with the LIM Protein Hic-5/ARA55 PMC2247392__F2 Growth factors trigger local and long distance signalling ENSG00000163930 ENSG00000146648 PMC6190593__F2 Immunity in Drosophila melanogaster — from microbial recognition to whole- organism physiology ENSG00000291507 ENSG00000172936 ENSG00000168040 PMC7553635__F6 Activating Wnt and inhibiting Hippo pathway by cytosolic PWP1 ENSG00000004975 ENSG00000136045 ENSG00000137673 ENSG00000168036 ENSG00000131023 ENSG00000196628 PMC3659569__F2 Ginseng and Diabetes: The Evidences from In Vitro, Animal and Human Studies ENSG00000150907 ENSG00000160741 ENSG00000026103 PMC6446989__F2 Biliary tract cancers: current knowledge, clinical candidates and future challenges ENSG00000066468 ENSG00000187682 ENSG00000157764 ENSG00000148400 ENSG00000074181 ENSG00000134982 ENSG00000148798 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000146648 ENSG00000254550 PMC9099918__F1 Novel Therapeutic Approaches with DNA Damage Response Inhibitors for Melanoma Treatment ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000123374 ENSG00000138385 PMC6826129__F7 Carcinoembryonic antigen‐related cell adhesion molecule 1 (CEACAM1) as a central mediator of vascular aging ENSG00000086991 PMC6015651__F1 Domains and functions of MCPyV T antigens ENSG00000239732 ENSG00000136997 ENSG00000116990 ENSG00000035928 PMC2976970__F3 Protein-protein interaction map of Notch transcription modifiers ENSG00000136807 ENSG00000108298 ENSG00000182774 ENSG00000089472 ENSG00000151461 ENSG00000042429 ENSG00000178028 ENSG00000157106 ENSG00000278270 ENSG00000132964 ENSG00000169375 ENSG00000112742 PMC4875723__F6 Systematic model of the Hippo/YAP signaling pathway affecting cytotoxic drug resistance in osteosarcoma cells ENSG00000150457 ENSG00000131023 PMC12141490__F9 Neural controlled tear secretion from lacrimal gland ENSG00000175567 ENSG00000167419 PMC9640682__F4 MiR-27a as a diagnostic biomarker and potential therapeutic target in systemic sclerosis ENSG00000019991 ENSG00000170558 ENSG00000168036 ENSG00000175104 ENSG00000168610 PMC5803335__F3 Cytoplasmic APC and the WNT signaling pathway ENSG00000134982 ENSG00000168036 PMC10987773__F5 Hepatic protein and amino acid metabolic pathway during pregnancy ENSG00000116044 ENSG00000108443 PMC7972934__F7 Mechanistic illumination of the inhibitory role of VB in GBMVB promotes the expression of miR-7-5p in GBM cells and facilitates the delivery of miR-7-5p by exosomes to recipient GBM cells ENSG00000170558 ENSG00000132646 ENSG00000100985 ENSG00000146648 PMC10987773__F4 Hepatic lipid metabolic pathway during pregnancy ENSG00000167772 ENSG00000171105 ENSG00000042832 ENSG00000167910 PMC10987773__F3 Hepatic glucose metabolic pathway during pregnancy ENSG00000167772 ENSG00000171105 ENSG00000288174 ENSG00000169047 PMC4288710__F7 Systems Level Analysis of Systemic Sclerosis Shows a Network of Immune and Profibrotic Pathways Connected with Genetic Polymorphisms ENSG00000011422 ENSG00000170458 ENSG00000168297 ENSG00000043462 ENSG00000121966 PMC8799556__F6 Integrin-linked kinase (ILK): the known vs. the unknown and perspectives ENSG00000132323 ENSG00000070831 ENSG00000164327 ENSG00000026103 PMC11899901__F4 KEGG pathway map showing the differentially spliced genes within the adrenergic signaling pathway in the heart ENSG00000041982 ENSG00000105711 ENSG00000174233 ENSG00000198626 ENSG00000087460 PMC8064971__F2 Targeting protein-protein interaction interfaces in COVID-19 drug discovery ENSG00000140564 ENSG00000130234 ENSG00000184012 PMC11903262__F2 Protective role of Trem2 in different models of myocardial injury PMC3010754__F1 Effect of Host Genetic Variation on the Pharmacokinetics and Clinical Response of Non-nucleoside Reverse Transcriptase Inhibitors ENSG00000197408 ENSG00000140505 ENSG00000255974 PMC8562402__F1 Therapeutic effect of oxygen-ozone in controlling of COVID-19 disease ENSG00000162711 ENSG00000132693 ENSG00000079999 PMC8750298__F3 Blood–Brain Barrier, an Evolving Concept Based on Technological Advances and Cell–Cell Communications ENSG00000281324 ENSG00000162337 PMC9319012__F11 RELA∙8-Oxoguanine DNA Glycosylase1 Is an Epigenetic Regulatory Complex Coordinating the Hexosamine Biosynthetic Pathway in RSV Infection ENSG00000100522 ENSG00000198380 ENSG00000173039 ENSG00000013375 PMC4546481__F4 Reactive stroma component COL6A1 is upregulated in castration-resistant prostate cancer and promotes tumor growth ENSG00000115415 PMC5729307__F2 Pathway signalling starts with the binding of insulin or growth factors to insulin receptors PMC8037405__F2 Key regulators and genetic pathways of phase transition from SAM to IM in cereal crops ENSG00000024422 ENSG00000125968 PMC9075957__F3 Interacting genes form a diet-responsive network affecting adipogenesis ENSG00000129757 ENSG00000053438 ENSG00000181104 ENSG00000113161 ENSG00000049860 ENSG00000122862 ENSG00000141655 PMC4685486__F3 Roles of Mitochondrial Damage-Associated Molecular Patterns in Diseases ENSG00000162711 ENSG00000239732 ENSG00000163568 ENSG00000125538 PMC8635032__F1 Recent Progress of Ferroptosis in Lung Diseases ENSG00000163930 ENSG00000181019 ENSG00000167468 ENSG00000167996 ENSG00000111684 ENSG00000168610 PMC8706767__F2 NF‐KB signaling in inflammation and cancer ENSG00000104856 ENSG00000183735 ENSG00000264522 ENSG00000102871 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC3901146__F1 Regulation of cellular stress-induced cell death pathways by IAPs ENSG00000132906 ENSG00000168040 ENSG00000164305 ENSG00000102172 ENSG00000276068 PMC3901146__F3 Role of IAPs in DNA damage response ENSG00000149311 ENSG00000168040 ENSG00000175104 PMC7438569__F5 Cardioprotection from NAD+ repletion ENSG00000143799 ENSG00000187531 ENSG00000105835 ENSG00000285109 ENSG00000096717 PMC7438569__F1 NAD+ metabolism in the heart ENSG00000105835 ENSG00000157064 ENSG00000173614 PMC2861866__F3 Hypothetical model linking multiple biological pathways in the development of SS-like disease based on differentially expressed genes identified in lacrimal glands by global microarray analyses ENSG00000103811 ENSG00000189058 ENSG00000107562 ENSG00000115415 ENSG00000163131 ENSG00000273686 ENSG00000168610 PMC3328908__F10 Diagram of canonical actin cytoskeleton signaling pathway ENSG00000112977 ENSG00000134982 ENSG00000138798 PMC5753157__F1 T-helper responses to A ENSG00000111537 ENSG00000137033 ENSG00000163599 ENSG00000107485 ENSG00000168610 ENSG00000106546 PMC3497295__F1 Selected signaling pathways in renal cell carcinoma (RCC) ENSG00000134086 ENSG00000138798 ENSG00000120868 PMC6384818__F6 NOD1 and TLR4 signaling pathways and the main target of CBN in the suppression of LPS-induced inflammation ENSG00000163739 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000106100 PMC10373067__F2 Bispecific antibody targeting TGFB and PD-L1 for synergistic cancer immunotherapy ENSG00000140564 PMC12125911__F7 Schematic diagram of VWA1 and Rac2’s roles in condylar cartilage under mechanical stress ENSG00000179403 ENSG00000154736 ENSG00000157766 ENSG00000171791 ENSG00000102678 PMC3296807__F1 Oncogenes and tumor suppressors associated with the regulation of autophagy ENSG00000002330 ENSG00000198793 ENSG00000167965 PMC6335350__F2 Therapeutic approaches in Alzheimer's disease: GSK3 Inactivation therapy: Neuroprotective compounds such as curcumin modulates PI3K/Akt/GSK3B pathway, leading to inactivation of tau hyperphosphorylation ENSG00000198793 ENSG00000096717 PMC6028070__F1 Cytokine signaling and their major negative regulators ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC6335350__F1 Interplay between mTOR, AB and Tau in Alzheimer's disease ENSG00000169047 ENSG00000198793 PMC4463992__F3 Most possible acting pathway of p42.3 protein by optimization of Bayes theorem ENSG00000125817 ENSG00000134086 ENSG00000196754 ENSG00000163914 PMC7969667__F10 Schematic model of RipA depicting possible interaction of RipA with surface immune receptor TLR4 and emanating downstream cascades ENSG00000073578 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC7662708__F5 Kynurenine Induces Osteoclastogenesis Via the AhR Signaling Pathway ENSG00000131196 ENSG00000106546 PMC7170981__F5 Evaluation of genes regulated by butyrate in controls and patients with UC ENSG00000023445 ENSG00000162711 ENSG00000104365 ENSG00000115008 ENSG00000137275 ENSG00000109320 ENSG00000173039 ENSG00000150455 ENSG00000049768 ENSG00000121879 ENSG00000127666 ENSG00000150782 ENSG00000169245 ENSG00000108691 ENSG00000239732 ENSG00000115415 ENSG00000187554 ENSG00000102245 ENSG00000164400 ENSG00000169429 ENSG00000175104 ENSG00000115594 PMC8280132__F3 System biology approach based on metabolic biomarkers and protein–protein interactions for identifying pathways underlying schizophrenia and bipolar disorder ENSG00000198380 ENSG00000115419 PMC4463992__F2 Primary regulatory networks ENSG00000125817 ENSG00000134086 ENSG00000196754 ENSG00000163914 ENSG00000185591 PMC5474285__F1 Workflow: network analysis, relevant organ location network analysis, gene ontology, and pathway analysis were performed on active compounds identified in Pulsatillae Radix (PR) by screening and target fishing ENSG00000002330 ENSG00000134982 ENSG00000117400 ENSG00000198670 PMC5474285__F5 Network pathway: pathway enrichment analysis was performed ENSG00000167207 ENSG00000134982 ENSG00000136869 ENSG00000168610 PMC7814589__F6 Signaling pathways regulating short stature in the Debao pony ENSG00000171105 ENSG00000112280 ENSG00000112964 ENSG00000125735 ENSG00000176887 ENSG00000162551 ENSG00000137841 ENSG00000139219 ENSG00000125398 ENSG00000291972 ENSG00000008516 ENSG00000165409 ENSG00000170893 ENSG00000172936 ENSG00000100985 ENSG00000163501 ENSG00000049089 PMC8066113__F2 Interactions between proteins, cells, and lentiviral infection for the GIMAP2 gene in PBNCs, as analyzed by the Pathway Studio program ENSG00000104432 ENSG00000168685 PMC7535138__F2 Intracellular signal transduction of adipokines and insulin resistance ENSG00000169047 ENSG00000168610 PMC4129373__F1 Schematic cartoon of TLR signaling pathways ENSG00000174123 ENSG00000174125 ENSG00000135218 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000172005 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC9029125__F2 Impact of Treadmill Interval Running on the Appearance of Zinc Finger Protein FHL2 in Bone Marrow Cells in a Rat Model: A Pilot Study ENSG00000291971 ENSG00000102349 ENSG00000185591 PMC4900422__F1 Constitutive CBM signaling in B- and T-cell malignancies ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000050405 PMC7744297__F2 AChR clustering and dispersal pathways ENSG00000134569 ENSG00000030304 ENSG00000099942 PMC7744297__F4 Simplified representation of the AChR pentamer and the N-glycosylation pathway of proteins and CMS-related genes (red color) ENSG00000101901 ENSG00000000419 ENSG00000172269 ENSG00000120697 ENSG00000173540 ENSG00000253710 ENSG00000198380 ENSG00000119523 ENSG00000139133 ENSG00000163933 ENSG00000088035 ENSG00000214160 ENSG00000136908 ENSG00000182858 PMC6960179__F5 Molecular evidence of inflammatory response and resolution of inflammation during MAP infection ENSG00000168884 ENSG00000167207 ENSG00000102871 ENSG00000091106 ENSG00000127191 ENSG00000168610 ENSG00000136826 ENSG00000007171 ENSG00000197461 ENSG00000056558 ENSG00000134070 ENSG00000136869 ENSG00000175104 ENSG00000090376 PMC8836182__F1 Molecular Mechanisms, Biomarkers and Emerging Therapies for Chemotherapy Resistant TNBC ENSG00000002330 ENSG00000168036 ENSG00000118777 ENSG00000146648 ENSG00000140443 PMC3748035__F1 Dynamic regulation of P2X4 receptors in microglia ENSG00000111537 ENSG00000166278 PMC7242206__F2 Possible targets of the androgen pathway for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) prophylaxis and adjuvant therapy ENSG00000130234 ENSG00000184012 PMC8836182__F2 Molecular Mechanisms, Biomarkers and Emerging Therapies for Chemotherapy Resistant TNBC ENSG00000138795 ENSG00000168036 ENSG00000196628 PMC2641000__F4 Cell-Autonomous Requirement for Rx Function in the Mammalian Retina and Posterior Pituitary ENSG00000043355 ENSG00000138083 PMC8303665__F2 Trastuzumab Mechanism of Action; 20 Years of Research to Unravel a Dilemma ENSG00000291971 ENSG00000146648 PMC10178469__F2 Downstream signaling pathway of TLRs ENSG00000239732 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC11754255__F2 Primary role process of CCL2 in fibrotic diseases ENSG00000144648 ENSG00000108691 ENSG00000074181 ENSG00000130234 ENSG00000137077 PMC5952217__F2 Kynurenine pathway is initiated by the oxidation of tryptophan via the enzymes IDO and TDO, with downstream catabolites having toxic, antioxidant and cell-protective activity ENSG00000111537 ENSG00000168036 ENSG00000106546 PMC11754255__F1 CCL2/CCR2 axis and its associated signaling pathways ENSG00000108691 ENSG00000198793 ENSG00000121807 ENSG00000168610 PMC5952217__F1 A schematic illustrating some of the factors proposed to affect obesity and carcinogenesis ENSG00000111537 ENSG00000125538 ENSG00000198793 ENSG00000168036 ENSG00000168610 ENSG00000106546 ENSG00000026103 PMC6269289__F1 A simplified diagram of sialic acid metabolism in human ENSG00000159921 ENSG00000170191 ENSG00000111726 ENSG00000164414 ENSG00000119899 ENSG00000095380 PMC2741489__F5 Known components of the IFN signalling pathway and explanation of observed results ENSG00000175329 PMC6446705__F2 Pathways modulating NAD+ levels in mammals ENSG00000143799 ENSG00000123572 ENSG00000278488 PMC4546458__F7 CXCL16/CXCR6 chemokine signaling mediates breast cancer progression by pERK1/2-dependent mechanisms ENSG00000161921 PMC2220082__F2 Rosilitazone stimulates NSCLC proliferation by affecting the Akt/mTOR pathway through PPARGamma-dependent and PPARGamma-independent mechanisms ENSG00000198793 PMC2153436__F4 Immune Response and Cell Cycle Networks ENSG00000134339 ENSG00000291971 ENSG00000163599 ENSG00000145386 ENSG00000166851 ENSG00000122194 ENSG00000230034 ENSG00000182326 ENSG00000012048 ENSG00000186575 ENSG00000066336 ENSG00000148773 ENSG00000089685 ENSG00000051180 ENSG00000076382 ENSG00000114346 ENSG00000291559 ENSG00000166278 ENSG00000117399 ENSG00000157131 ENSG00000276043 ENSG00000117724 ENSG00000198901 ENSG00000117650 ENSG00000013810 ENSG00000288512 ENSG00000175104 PMC11667047__F1 Therapeutic potential of 5-aminolevulinic acid in metabolic disorders: Current insights and future directions ENSG00000144659 ENSG00000135776 ENSG00000144410 ENSG00000066926 ENSG00000126088 ENSG00000188690 ENSG00000115657 PMC4844852__F1 Environmental Exposures – The Missing Link in Immune Responses After Transplantation ENSG00000140505 ENSG00000140465 ENSG00000106546 PMC11667047__F2 Molecular mechanisms underlying the physiological and pharmacological effects of 5-ALA (in the presence of Fe2+)The green line indicates positive regulation, the red line indicates inhibition, the dashed line represents indirect effects ENSG00000186716 ENSG00000169047 ENSG00000175567 ENSG00000079999 PMC8067556__F1 WW domain-containing oxidoreductase (WWOX) interaction partners and signaling pathways in the nervous system ENSG00000134982 ENSG00000168036 PMC5837599__F3 Typical structure and content of exosomes ENSG00000110651 ENSG00000010278 ENSG00000135404 PMC11106351__F9 Anti-hepatitis B virus mechanism of dopamine ENSG00000184845 ENSG00000187608 ENSG00000115415 PMC4825016__F7 Proposed model for cross-talk of IGF1 and integrin signaling ENSG00000291971 ENSG00000140443 PMC5099148__F1 Biosynthetic pathway of pharmaceutical terpenoids ENSG00000110921 ENSG00000197721 ENSG00000119912 PMC2775047__F1 TLR Mediated Immune Responses in the Urinary Tract ENSG00000170458 ENSG00000172005 ENSG00000172936 ENSG00000150455 ENSG00000175104 PMC7392886__F2 Development of immunothrombosis.Platelets activated by thrombin and or PICs initiate (PAR)–mediated signalling further increasing levels of PICs VWF and TF coupled with suppression of suppression of thrombomodulin ENSG00000003436 ENSG00000122194 PMC5028879__F1 NOD2 senses MDP and elicits immune responses ENSG00000167207 ENSG00000175104 PMC6530647__F4 Carbon monoxide controls metabolic homeostasis via the PERK-eIF2Alpha-ATF4-FGF21, SENS2, and REDD1 pathway ENSG00000128272 ENSG00000144895 ENSG00000105550 ENSG00000285069 PMC7759159__F1 NFKB activation is central to the acute respiratory RNA virus-induced cytokine storm ENSG00000102871 ENSG00000130234 ENSG00000184012 ENSG00000172936 ENSG00000136869 ENSG00000162692 ENSG00000276561 ENSG00000010671 ENSG00000164342 PMC4782048__F7 Model depicting how AMPK regulates cell fate decisions through lysosome-dependent control of Wnt signaling ENSG00000164736 ENSG00000198793 ENSG00000112561 ENSG00000168036 PMC9366225__F1 CXCR6-based immunotherapy in autoimmune, cancer and inflammatory infliction ENSG00000198793 ENSG00000137845 PMC8507548__F1 Overcoming Immunotherapy Resistance by Targeting the Tumor-Intrinsic NLRP3-HSP70 Signaling Axis ENSG00000162711 ENSG00000136869 ENSG00000168610 PMC5809980__F4 Diagram illustrates the dominating signaling pathways involving Sal- induced autophagy ENSG00000101255 ENSG00000198793 ENSG00000155792 PMC5596442__F2 Two strategies for photoactivation of cell signaling pathways ENSG00000124102 PMC4661823__F3 ER stress sensors and Programmed Cell Death in animals ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC9365022__F5 Doxorubicin-Induced Cardiotoxicity May Be Alleviated by Bone Marrow Mesenchymal Stem Cell-Derived Exosomal lncRNA via Inhibiting Inflammation ENSG00000149311 ENSG00000169291 ENSG00000188992 ENSG00000112378 PMC4899745__F1 Efficient production of acetoin in Saccharomyces cerevisiae by disruption of 2,3-butanediol dehydrogenase and expression of NADH oxidase ENSG00000275544 PMC6237873__F5 LncRNA-mRNA interaction networks ENSG00000163914 ENSG00000177606 PMC8231864__F1 Current Understandings of Core Pathways for the Activation of Mammalian Primordial Follicles PMC5564566__F6 Activation of signal transducer and activator of transcription 3 (STAT3) signaling in EGFR mutant non-small-cell lung cancer (NSCLC) ENSG00000074181 ENSG00000138798 ENSG00000114315 PMC9266941__F1 Pathophysiology and Emerging Molecular Therapeutic Targets in Heterotopic Ossification ENSG00000170365 PMC5495797__F7 Differences and commonalities in TLR4- and FcERI-activated production of proinflammatory cytokines ENSG00000213658 ENSG00000172005 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000175104 PMC5722026__F1 PCP and SHH Signaling pathways ENSG00000166813 ENSG00000128602 PMC1698511__F3 PKR is an intermediary component in TLR signaling ENSG00000172936 ENSG00000157625 ENSG00000107201 ENSG00000150455 ENSG00000175104 ENSG00000276561 PMC7699852__F1 Simplified representation of aryl hydrocarbon receptor (AhR) pathways ENSG00000171759 ENSG00000168036 ENSG00000140465 ENSG00000106546 PMC9076607__F2 OPG-related signaling pathways ENSG00000110799 ENSG00000082512 ENSG00000168036 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000131196 PMC5329766__F2 Understanding the intersections between metabolism and cancer biology ENSG00000173599 ENSG00000102967 ENSG00000115419 PMC7699852__F4 Deleterious effects of aryl hydrocarbon receptor (AhR) activation in asthma ENSG00000169429 ENSG00000145777 ENSG00000106546 PMC10975298__F4 Signaling pathways against resistant cancer ENSG00000087245 ENSG00000159224 ENSG00000002330 ENSG00000148400 ENSG00000166813 ENSG00000198793 ENSG00000123374 ENSG00000100985 ENSG00000128602 ENSG00000146648 ENSG00000026103 PMC5797591__F1 Schematic overview of the roles of the Notch pathway in CD8+ T cells and its application to immunotherapy ENSG00000111537 ENSG00000114315 ENSG00000135144 PMC5380330__F4 MicroRNA profiling of CD3+CD56+ cytokine-induced killer cells ENSG00000099985 ENSG00000213658 ENSG00000180644 PMC3665230__F6 Pathway members of insulin/Akt signalling, TGFB, wnt signalling and inflammatory pathways that were regulated by prednisolone in 3T3-L1 cells ENSG00000169245 ENSG00000138795 ENSG00000163251 ENSG00000155011 ENSG00000108688 ENSG00000174804 ENSG00000157240 PMC10975298__F1 Mechanisms of drug resistance in cancer cells ENSG00000184207 PMC7286536__F1 Insulin regulates glycolysis through both AKT-dependent and AKT-independent mechanisms ENSG00000002330 ENSG00000265972 ENSG00000159399 PMC9218457__F6 Exosomes Derived From Mesenchymal Stem Cells Pretreated With Ischemic Rat Heart Extracts Promote Angiogenesis via the Delivery of DMBT1 ENSG00000178860 ENSG00000142677 ENSG00000168036 ENSG00000187908 ENSG00000168610 PMC5541666__F1 Details from the STRING interaction diagrams within the global transcriptome profiles of Pink1-deficient mouse cerebellar tissue ENSG00000022567 ENSG00000166111 ENSG00000137135 ENSG00000050748 ENSG00000115350 ENSG00000100744 ENSG00000118873 ENSG00000157240 ENSG00000148229 ENSG00000157227 ENSG00000164002 ENSG00000160360 ENSG00000106628 ENSG00000240682 ENSG00000050405 ENSG00000104497 ENSG00000111605 ENSG00000196090 ENSG00000100906 ENSG00000269335 ENSG00000114030 ENSG00000065559 ENSG00000137872 ENSG00000213341 ENSG00000107175 ENSG00000170638 ENSG00000181027 ENSG00000153885 ENSG00000117020 ENSG00000115415 ENSG00000176463 ENSG00000107372 ENSG00000153012 ENSG00000188529 ENSG00000275272 ENSG00000083799 ENSG00000133135 ENSG00000165494 PMC2946555__F2 Merlin, a “Magic” Linker Between the Extracellular Cues and Intracellular Signaling Pathways that Regulate Cell Motility, Proliferation, and Survival ENSG00000131023 PMC6476910__F2 DAMPs exposure ENSG00000128272 ENSG00000144895 ENSG00000067900 ENSG00000110218 ENSG00000057663 PMC8905584__F10 To detect potential pathways and target genes in infantile Pompe patients using computational analysis ENSG00000110395 ENSG00000134982 ENSG00000242866 ENSG00000089159 PMC7913036__F1 Iron cycle in the tumor microenvironment (TME) ENSG00000177575 ENSG00000148346 ENSG00000125538 ENSG00000168610 PMC3276621__F2 Pathways for the synthesis of glycerolipids and their subcellular localization ENSG00000083857 ENSG00000124102 ENSG00000163624 ENSG00000087157 ENSG00000146005 ENSG00000173599 ENSG00000184207 ENSG00000166123 PMC12108002__F2 Major signaling pathways and transcription factors in BMSCs ENSG00000157933 ENSG00000145321 ENSG00000168036 PMC5405066__F7 Hypothetical mechanism of action of BoNT/A is achieved through the modulation of TLR2 and SNARE proteins, and minocycline occurs through the modulation of p38 and MMP9 in glial cells ENSG00000136869 ENSG00000137496 PMC3391329__F3 Proteome coverage of the KEGG ‘Insulin Signaling’ pathway ENSG00000171105 ENSG00000002330 ENSG00000110395 ENSG00000197721 ENSG00000150907 ENSG00000198793 ENSG00000164087 ENSG00000026103 PMC11977922__F1 Signaling mechanism of the canonical cGAS-STING pathway and its downstream effects in diseases ENSG00000183735 ENSG00000164430 PMC11977922__F2 Mechanisms by which lipid metabolism regulates the STING signalling pathway ENSG00000164430 ENSG00000172594 PMC3180192__F2 TGFB pathway genes in iMYC cells ENSG00000128016 ENSG00000169071 ENSG00000164761 ENSG00000173156 ENSG00000134871 ENSG00000168610 ENSG00000166033 ENSG00000144677 ENSG00000170365 ENSG00000095739 ENSG00000111799 ENSG00000111341 ENSG00000108821 ENSG00000135919 PMC11977922__F4 Mechanism through which STING activation leads to insulin resistance ENSG00000137713 ENSG00000146416 ENSG00000183735 ENSG00000169047 ENSG00000161999 PMC7174681__F3 Effects of mTOR inhibition are shown ENSG00000135446 ENSG00000169047 ENSG00000155792 ENSG00000105810 PMC7174681__F2 Dashed lines indicate a decreased interaction between two components or a diminished function ENSG00000135446 ENSG00000169047 ENSG00000155792 ENSG00000105810 PMC5137585__F2 Diabetic cardiomyopathy: signaling defects and therapeutic approaches ENSG00000169047 ENSG00000198793 PMC7174681__F1 ER, mTOR, and CDK4/6 pathways and their links are shown ENSG00000135446 ENSG00000169047 ENSG00000155792 ENSG00000167965 ENSG00000105810 PMC7797765__F1 Simplified overview of the complement pathway ENSG00000039537 PMC3141028__F4 13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation ENSG00000122966 ENSG00000105656 PMC10743075__F10 n-3-PUFA administration decreased mRNA expression of pro-inflammatory cytokines, as documented in the TNF signaling pathway ENSG00000183763 ENSG00000167207 ENSG00000102871 ENSG00000164136 ENSG00000007908 ENSG00000131323 ENSG00000128342 ENSG00000168040 ENSG00000168404 ENSG00000163295 ENSG00000164305 PMC3909817__F4 Potential mechanisms of TGF-Beta-induced upregulation of Nox4 gene expression ENSG00000086991 PMC7943311__F6 Signaling pathways critical for the roles and differentiation of Th9 cells and Treg cells in solid tumor ENSG00000150907 ENSG00000198793 ENSG00000049768 ENSG00000104432 ENSG00000026103 PMC5325806__F2 Intersections of Post-Transcriptional Gene Regulatory Mechanisms with Intermediary Metabolism ENSG00000165119 ENSG00000150907 ENSG00000096717 PMC9482322__F7 Super-enhancer-associated INSM2 regulates lipid metabolism by modulating mTOR signaling pathway in neuroblastoma ENSG00000182718 ENSG00000198793 ENSG00000169710 ENSG00000099194 PMC7452942__F2 Soluble protein sensors built by means of bottom-up approaches ENSG00000077782 PMC4999974__F7 PAC-1 enhances the apoptotic signal as induced by cytotoxins such as doxorubicin ENSG00000084774 PMC7601316__F1 Tumor necrosis factorA (TNFA) downstream signaling pathway mediated by two TNFA receptors, TNFR1 and TNFR2, and by membrane form of TNFA (mTNFA) reverse signaling ENSG00000102871 ENSG00000131323 ENSG00000127191 PMC3701226__F2 Signaling pathways triggered by TCR and CD28 engagement ENSG00000124181 PMC5541666__F3 Systematic analysis of key factors in the mitochondria-associated innate immunity pathway, using acute starvation of human SH-SY5Y neuroblastoma cells to reveal the transcriptional regulation of stress responses and their dependence on PINK1 ENSG00000088888 ENSG00000134321 ENSG00000102871 ENSG00000158828 ENSG00000185745 ENSG00000276561 ENSG00000171109 PMC8825370__F4 Recent Progress in Understanding the Action of Natural Compounds at Novel Therapeutic Drug Targets for the Treatment of Liver Cancer ENSG00000198793 ENSG00000196712 PMC8825370__F3 Recent Progress in Understanding the Action of Natural Compounds at Novel Therapeutic Drug Targets for the Treatment of Liver Cancer ENSG00000002330 ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC7433817__F6 Schematic chart of drug sensitivity‐related genes in the current study with proposed interaction or regulatory pathway in ccRCC ENSG00000167601 ENSG00000197324 ENSG00000198793 ENSG00000087460 PMC8304139__F3 NFKB—An Important Player in Xenoestrogen Signaling in Immune Cells ENSG00000104856 ENSG00000186716 PMC7118125__F3 Signaling networks in immunometabolism ENSG00000177169 ENSG00000168958 ENSG00000052795 ENSG00000110931 ENSG00000168036 ENSG00000217128 PMC11126125__F4 Immune response induced by DTMUV infection and its immune evasion ENSG00000183735 ENSG00000088888 ENSG00000119401 ENSG00000169871 PMC3185015__F9 RSPO1/Beta-Catenin Signaling Pathway Regulates Oogonia Differentiation and Entry into Meiosis in the Mouse Fetal Ovary ENSG00000169218 ENSG00000168036 ENSG00000188425 ENSG00000102678 PMC8369065__F1 Mycobacterium-Induced Th1, Helminths-Induced Th2 Cells and the Potential Vaccine Candidates for Allergic Asthma: Imitation of Natural Infection ENSG00000134982 ENSG00000136869 PMC2699853__F1 Diabetes alters the expression of multiple genes of the TGFB pathway (left side of the panel) and BMPs pathway (right side) in rat retinal vessels ENSG00000057252 ENSG00000107779 ENSG00000111145 ENSG00000159128 ENSG00000037965 ENSG00000148400 ENSG00000026508 ENSG00000265972 PMC4643662__F2B Proposed signaling mechanisms of S100A8/A9 in pancreatic-cancer cells.S100A8/A9 could interact with RAGE, leading to the activation of MAP kinases and NF̃KB signaling ENSG00000143546 ENSG00000163220 ENSG00000198793 ENSG00000136869 PMC4692127__F8 Downregulation of the Canonical WNT Signaling Pathway by TGFB1 Inhibits Photoreceptor Differentiation of Adult Human Müller Glia with Stem Cell Characteristics ENSG00000168036 ENSG00000111186 ENSG00000134245 PMC5220431__F4 The HH signaling pathway in lung cancer ENSG00000163558 ENSG00000128602 PMC5220431__F2 HH signaling pathway during development ENSG00000106571 ENSG00000144857 ENSG00000128602 PMC8825370__F1 Recent Progress in Understanding the Action of Natural Compounds at Novel Therapeutic Drug Targets for the Treatment of Liver Cancer ENSG00000138798 ENSG00000198793 ENSG00000136869 ENSG00000171791 PMC3306451__F2 Integration of mitochondrial oxidative and antioxidant pathways by PGC-1A ENSG00000096717 ENSG00000142082 PMC8032984__F2 B7-H3 increases ROS and HIF-1A through B7-H3-induced Nrf2 suppression, SOD1, SOD2, and PRX3 reduction, thus promote aerobic glycolysis in cancer cells, leading to tumor growth ENSG00000105329 ENSG00000134982 ENSG00000198793 PMC8536186__F6 Fractionated Seminal Plasma of Boar Ejaculates Analyzed by LC–MS/MS: Its Effects on Post-Thaw Semen Quality ENSG00000162889 ENSG00000149311 ENSG00000121552 ENSG00000019582 ENSG00000111581 ENSG00000142192 ENSG00000100934 ENSG00000291836 ENSG00000126883 ENSG00000081189 ENSG00000163631 PMC2818238__F1 Heteromerization of dopamine D2 receptors with dopamine D1 or D5 receptors generates intracellular calcium signaling by different mechanisms ENSG00000173599 ENSG00000167434 PMC7226273__F5 Proposed mechanism for Vinorelbine’s radio sensitizing effect ENSG00000149311 ENSG00000175054 PMC8051751__F6 Molecular mechanisms induced by sirt1 inhibition in ACC cells ENSG00000170558 ENSG00000140443 PMC7774512__F3 Working hypothesis of Glial Molecular Mechanisms Implicated in the Pathogenesis of POI ENSG00000125538 PMC8063300__F1 Aryl hydrocarbon receptor in central nervous system tumors: Biological and therapeutic implications ENSG00000104856 ENSG00000110711 ENSG00000181019 ENSG00000173039 ENSG00000140465 ENSG00000106546 PMC11687167__F4 Signaling pathways associated with PCSK9 during the immune response (created in https://BioRender ENSG00000138378 ENSG00000115415 ENSG00000136869 ENSG00000168610 ENSG00000131196 ENSG00000169174 PMC7926563__F2 Therapeutic agents targeting the B-cell receptor (BCR) signaling pathway in follicular lymphoma ENSG00000186716 PMC9020237__F1 Emerging role of the itaconate-mediated rescue of cellular metabolic stress ENSG00000198829 ENSG00000125538 ENSG00000162772 PMC8306340__F5 Altered Electrical, Biomolecular, and Immunologic Phenotypes in a Novel Patient-Derived Stem Cell Model of Desmoglein-2 Mutant ARVC ENSG00000104365 ENSG00000109320 ENSG00000101265 ENSG00000103035 ENSG00000269335 ENSG00000173039 ENSG00000213341 ENSG00000135341 ENSG00000127191 ENSG00000006062 ENSG00000110801 ENSG00000215021 ENSG00000150782 ENSG00000226275 ENSG00000077150 ENSG00000135960 ENSG00000263528 ENSG00000149273 ENSG00000131323 ENSG00000083799 ENSG00000162692 ENSG00000041357 ENSG00000068878 ENSG00000189067 PMC9006990__F2 Anti-EGFR Monoclonal Antibody in mCRC Maintenance Therapy ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC1828869__F2 Regulation of induction and vesicle nucleation ENSG00000126775 PMC3889251__F9 New proposed model of BMP2-induced C2C12 cells differentiation ENSG00000198793 PMC9701395__F9 Computation and molecular pharmacology to trace the anti-rheumatoid activity of Angelicae Pubescentis Radix ENSG00000132906 ENSG00000002330 ENSG00000070831 ENSG00000291971 PMC5864196__F3 Potential metabolic capabilities ENSG00000122966 ENSG00000172005 ENSG00000171540 PMC2663056__F4 Fuzzy Logic Analysis of Kinase Pathway Crosstalk in TNF/EGF/Insulin-Induced Signaling ENSG00000138798 ENSG00000169047 ENSG00000064012 ENSG00000164305 PMC3889251__F1 BMP2 signaling pathway resulting in osteogenesis or adipogenesis ENSG00000107779 PMC4089092__F1 Toll-like receptor (TLR) signaling pathway ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC7521272__F4 Pathway analysis of the differentially expressed proteins between the gastric cancer (T) and adjacent tissues (P) ENSG00000169021 ENSG00000090402 ENSG00000147684 ENSG00000140740 ENSG00000073578 ENSG00000130414 ENSG00000184983 ENSG00000117118 ENSG00000138495 ENSG00000292058 ENSG00000004779 ENSG00000006695 ENSG00000143252 ENSG00000164405 ENSG00000213619 ENSG00000151366 ENSG00000184752 ENSG00000099795 PMC10239510__F7 Paradigm summarizing the thermogenic and anti-inflammatory properties of YJT via the gut microbiota and related multiple signaling pathways ENSG00000008438 ENSG00000167207 ENSG00000142611 ENSG00000132646 ENSG00000136869 ENSG00000161031 ENSG00000196689 PMC2663056__F3 Fuzzy Logic Analysis of Kinase Pathway Crosstalk in TNF/EGF/Insulin-Induced Signaling ENSG00000138798 ENSG00000064012 PMC4821196__F2 Summary of the intracellular signaling cascades that occur within neurons and glia within the brain ENSG00000205221 ENSG00000198793 ENSG00000177606 ENSG00000157005 PMC9322149__F4 Exploring Quercetin Anti-Osteoporosis Pharmacological Mechanisms with In Silico and In Vivo Models ENSG00000139610 ENSG00000078747 ENSG00000102871 ENSG00000007908 ENSG00000128342 ENSG00000168040 ENSG00000127191 PMC3758473__F5 The Genetics of Mammalian Circadian Order and Disorder: Implications for Physiology and Disease ENSG00000149311 ENSG00000136997 PMC10552637__F1 Metabolic cycle of tetrahydrofolate (THF) and the one-carbon (C1) metabolic pathway ENSG00000065911 ENSG00000100714 ENSG00000145020 ENSG00000120254 PMC2737697__F2 Genetic Susceptibility to Lupus: New Insights from fine mapping and genome-wide association studies ENSG00000138378 ENSG00000118503 ENSG00000186716 ENSG00000132693 ENSG00000276561 ENSG00000186827 PMC11903573__F2 HDACs and KATs that are involved in adipose tissue regulation ENSG00000142611 ENSG00000150907 ENSG00000187288 PMC11903573__F3 KATs and HDACs play a role in glucose tolerance and insulin resistance ENSG00000094631 ENSG00000171720 ENSG00000168066 ENSG00000150907 ENSG00000169047 ENSG00000136869 ENSG00000077463 ENSG00000096717 ENSG00000163517 PMC4796178__F1 Exercise-induced autophagy signaling ENSG00000198793 ENSG00000112561 ENSG00000096717 PMC6838412__F7 Proposed mechanisms in SS MSG ENSG00000088888 ENSG00000156976 ENSG00000276561 ENSG00000113360 PMC4449431__F8 Schematic model illustrating the possible pathway targeting NCI-H929 cell by HM910 ENSG00000002330 ENSG00000135446 ENSG00000105810 PMC9136877__F6 Unlocking the Untapped Potential of Endothelial Kinase and Phosphatase Involvement in Sepsis for Drug Treatment Design ENSG00000167601 ENSG00000291971 ENSG00000154188 PMC3758473__F2 Genetics of Mammalian Circadian Order and Disorder: Implications for Physiology and Disease ENSG00000005812 ENSG00000132326 PMC7668088__F9 Conceptual model of OR2W3-evoked ASM relaxation and bronchodilation ENSG00000171105 ENSG00000167323 ENSG00000293604 ENSG00000238243 ENSG00000001626 PMC8107117__F5 YAP1 and its fusion proteins in cancer initiation, progression and therapeutic resistance ENSG00000150457 ENSG00000131023 PMC8201174__F3 Molecular Pathogenesis of Pulmonary Fibrosis, with Focus on Pathways Related to TGFB and the Ubiquitin-Proteasome Pathway ENSG00000145604 ENSG00000103266 ENSG00000086991 ENSG00000197299 PMC8345866__F8 Summary scheme for potential drugs to target the Wnt-AMPK-mTOR pathway during epileptogenesis ENSG00000198793 ENSG00000102312 ENSG00000168036 ENSG00000104332 ENSG00000176165 PMC6646331__F5 Glutamatergic synapse (path:hsa04724) pathway mapping of the protein targets of DPCs: The location of protein targets of DPCs in the KEGG pathway hsa04724 is represented in yellow and red coloured boxes, red ones are specific to mGluRs ENSG00000276559 ENSG00000118520 PMC7402353__F3 13 major receptor groups involved in itch and their endogenous pruritogens ENSG00000104321 ENSG00000078747 ENSG00000196689 PMC9409283__F2 Analysis of Amino Acids in the Roots of Tamarix ramosissima by Application of Exogenous Potassium (K+) under NaCl Stress ENSG00000122543 ENSG00000148926 PMC8336468__F7 Clostridium cellulovorans Proteomic Responses to Butanol Stress PMC5995146__F2 Parkinson’s disease: From human genetics to clinical trials ENSG00000100225 ENSG00000158828 ENSG00000069329 PMC3926967__F2 Differential effects of type I and II interferons on myeloid cells and resistance to intracellular bacterial infections ENSG00000105397 ENSG00000169047 ENSG00000168610 ENSG00000142166 PMC9224161__F4 Dietary Copper Deficiency Leads to Changes in Gene Expression Indicating an Increased Demand for NADH in the Prefrontal Cortex of the Rat’s Brain ENSG00000157184 ENSG00000125166 ENSG00000065833 ENSG00000173599 ENSG00000159399 ENSG00000060762 PMC4454159__F2 Concept map of the cancer metabolic rewiring ENSG00000065911 ENSG00000135423 ENSG00000122966 ENSG00000092621 ENSG00000172005 PMC3919979__F9 CNP action in the SRG ENSG00000173786 ENSG00000145321 ENSG00000001626 PMC7761947__F3 Signaling mechanisms for TRPM2 and TRPM8 activation PMC9326605__F1 DNA Hypomethylation May Contribute to Metabolic Recovery of Frozen Wood Frog Brains ENSG00000187605 ENSG00000138336 ENSG00000139372 PMC4454159__F1 Glutamine metabolic rewiring ENSG00000135423 ENSG00000122966 ENSG00000172005 ENSG00000112992 PMC4688904__F1 The glucocorticoid receptor, regulation of gene expression, and its clinical consequences ENSG00000284832 ENSG00000069667 PMC9224161__F2 Dietary Copper Deficiency Leads to Changes in Gene Expression Indicating an Increased Demand for NADH in the Prefrontal Cortex of the Rat’s Brain ENSG00000157184 ENSG00000125166 ENSG00000065833 ENSG00000173599 ENSG00000115419 ENSG00000159399 ENSG00000060762 PMC7761947__F2 TRPM1 role in visual pathways ENSG00000198793 ENSG00000110931 ENSG00000134160 PMC4102943__F6 The proposed point at which dFdC metabolism interacts with the Kennedy pathway that converts choline to phosphatidylcholine, resulting in formation of GdPC, and the impact of linoleate on that reaction ENSG00000158825 PMC7060963__F5 Transcriptomics and pathway analysis of CRISPLD1-KO-hiPSC-CM ENSG00000148798 ENSG00000163914 ENSG00000198626 ENSG00000198910 PMC11004819__F3 Pharmacogenomics-based systematic review of coronary artery disease based on personalized medicine procedure ENSG00000057252 ENSG00000138075 ENSG00000130208 ENSG00000110244 ENSG00000167910 ENSG00000113161 ENSG00000185615 ENSG00000073060 ENSG00000130164 ENSG00000138823 ENSG00000104549 ENSG00000100979 ENSG00000285482 ENSG00000143921 PMC11530992__F1 Canonical pathway and non-canonical pathway of NFKB signaling pathway ENSG00000186716 ENSG00000162924 PMC4385749__F5 Diagram of the neural circuitry underlying delay eyeblink conditioning ENSG00000173599 ENSG00000145321 ENSG00000062485 PMC6592230__F7 ATM/Chk/Greatwall/PP2A signaling model for normal mitotic exit (A) and for abnormal mitotic exit during recovery from mitotic DNA damage (B) ENSG00000149311 ENSG00000143420 ENSG00000166851 PMC6999766__F8 Schematic diagram summarizing the therapeutic effects of the flavonoid ingredients isolated from Abelmoschus manihot (L.) Medik flowers in multiple myeloma ENSG00000160883 ENSG00000159399 PMC4732610__F6 Transcriptional Analysis of T Cells Resident in Human Skin ENSG00000211445 ENSG00000051523 ENSG00000184470 ENSG00000116044 ENSG00000109320 ENSG00000086991 ENSG00000008394 ENSG00000100348 ENSG00000185591 ENSG00000277897 ENSG00000140465 ENSG00000158125 PMC4732610__F5 Transcriptional Analysis of T Cells Resident in Human Skin ENSG00000171855 ENSG00000081041 ENSG00000105329 ENSG00000163739 ENSG00000108342 ENSG00000164399 ENSG00000111537 ENSG00000164136 ENSG00000113520 ENSG00000184371 ENSG00000277263 ENSG00000164400 ENSG00000113525 PMC2861286__F1 Proposed mechanism for vitamin D’s action on the innate immune system ENSG00000174125 PMC2908542__F8 Sirtuin 3, a New Target of PGC-1A, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis ENSG00000142082 PMC8200410__F6 Ketogenic Metabolic Therapy, Without Chemo or Radiation, for the Long-Term Management of IDH1-Mutant Glioblastoma: An 80-Month Follow-Up Case Report ENSG00000125166 ENSG00000047936 ENSG00000083720 PMC4908334__F5 SBGN representation of the haematopoiesis gene regulatory network generated by ChiBE () based on our BioPAX model ENSG00000151702 ENSG00000157554 ENSG00000102145 ENSG00000137834 ENSG00000159216 ENSG00000152804 ENSG00000179348 ENSG00000179588 PMC11523104__F1 2–3% of glucose entering the cell is diverted from glycolysis into the hexosamine biosynthetic pathway (HBP) ENSG00000147162 ENSG00000198408 ENSG00000124357 PMC5547388__F5 MicroRNA expression analysis in endometriotic serum treated mesenchymal stem cells ENSG00000169291 ENSG00000002330 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000169752 PMC7326927__F10 Summary of the effects of MPP+ and rotenone exposure on IL4-induced immune response on primary glial cell cultures ENSG00000067057 ENSG00000091972 ENSG00000113520 ENSG00000163606 PMC4137222__F2 HBV interaction with the ER-associated degradation pathway ENSG00000134109 ENSG00000116406 ENSG00000088298 PMC8891559__F2 Necroptosis in alcoholic liver disease and hepatic pathogenesis ENSG00000147162 ENSG00000137275 ENSG00000130649 ENSG00000189403 ENSG00000168404 ENSG00000256646 ENSG00000285379 PMC8891559__F1 Necroptosis in alcoholic liver disease and hepatic pathogenesis ENSG00000162711 ENSG00000124256 ENSG00000081041 ENSG00000137275 ENSG00000102871 ENSG00000163739 ENSG00000168040 ENSG00000127191 ENSG00000142166 ENSG00000138032 ENSG00000189403 ENSG00000136869 ENSG00000083799 ENSG00000168404 ENSG00000285379 ENSG00000164342 PMC7307818__F7 Possible mechanisms responsible for the effects of paeonol against human colorectal cancer HCT116 cells ENSG00000135446 ENSG00000168036 ENSG00000105810 PMC6567800__F7 Anti-shock mechanisms of molecular hydrogen during sepsis ENSG00000105550 ENSG00000163914 ENSG00000136869 ENSG00000157017 PMC12027419__F5 Identification of key players in burn injury-related REC network ENSG00000275723 ENSG00000163686 ENSG00000117480 PMC7423769__F4 Proposed network for BMP signaling in regulating energy metabolism via mTOR and HIF-1 ENSG00000178860 PMC6567800__F6 Anti-apoptosis mechanisms of molecular hydrogen in sepsis ENSG00000172936 ENSG00000136869 PMC4944539__F1 FGF/FGFR signaling pathways ENSG00000115904 PMC5570368__F7 Cardiac transcriptome profiling of diabetic Akita mice using microarray and next generation sequencing ENSG00000177606 ENSG00000132170 PMC5216813__F6 Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer ENSG00000001630 ENSG00000036530 ENSG00000180432 ENSG00000135929 PMC8301600__F2 Alphaherpesvirus-mediated innate immune evasion ENSG00000174125 ENSG00000183735 ENSG00000164430 ENSG00000163568 ENSG00000110060 ENSG00000163565 ENSG00000172936 ENSG00000142166 PMC8966199__F8 Redox proteome analysis of auranofin exposed ovarian cancer cells (A2780) ENSG00000180210 ENSG00000291983 ENSG00000128272 ENSG00000113558 ENSG00000188404 ENSG00000127191 ENSG00000105669 ENSG00000198168 PMC2225983__F3 PI3K-AKT pathway is transcriptionally regulated throughout the lactation cycle ENSG00000002330 ENSG00000105401 ENSG00000198793 PMC5570368__F8 Cardiac transcriptome profiling of diabetic Akita mice using microarray and next generation sequencing ENSG00000132170 PMC8531217__F12 Sterols, Oxysterols, and Accessible Cholesterol: Signalling for Homeostasis, in Immunity and During Development ENSG00000130234 ENSG00000184012 PMC5274707__F1 Neutrophil crosstalk with immune and humoral cells and relevant chemical signals that influence and compose the inflammatory response and pathway to resolution via the neutrophil ENSG00000239732 ENSG00000138755 ENSG00000136869 ENSG00000005381 ENSG00000164342 PMC11751205__F5 Autophagy pathways in normal and burned tissues ENSG00000173726 ENSG00000158828 ENSG00000171109 ENSG00000135093 PMC8750666__F9 Building a Foundation for Precision Onco-Nutrition: Docosahexaenoic Acid and Breast Cancer ENSG00000177169 ENSG00000163435 ENSG00000171105 ENSG00000163914 ENSG00000169047 ENSG00000173599 PMC6580575__F4 Mechanistic diagram of NGF and ILM-mediated proliferation promotion by regulating cell cycle of Müller cells ENSG00000135446 ENSG00000123374 PMC8685280__F5 Insights into the post-translational modification and its emerging role in shaping the tumor microenvironment ENSG00000049768 PMC3000610__F6 Proposed working hypothesis ENSG00000063176 ENSG00000157933 ENSG00000136869 PMC9293537__F5 Pharmacological Approaches to Decelerate Aging: A Promising Path ENSG00000169047 ENSG00000116157 PMC6212521__F8 Schemes of normoxic vs ENSG00000172005 ENSG00000145321 ENSG00000062485 PMC5693908__F1 Inflammatory signaling pathways in hematopoietic cells and potential therapeutic targets for myeloid malignancies ENSG00000159128 ENSG00000213928 ENSG00000111537 ENSG00000102871 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000127191 ENSG00000168610 PMC11379071__F8 Diagram illustrating the underlying molecular mechanism identified in the present study ENSG00000128272 ENSG00000125107 ENSG00000198492 ENSG00000135069 ENSG00000150457 ENSG00000165819 PMC6212521__F7 Schemes of normoxic vs ENSG00000172005 ENSG00000062485 PMC5523465__F1A Checks and Balances: the Glucocorticoid Receptor and NFKB in Good Times and Bad ENSG00000004478 PMC4480752__F7 miR-93 Promotes Cell Proliferation in Gliomas through Activation of PI3K/Akt Signaling Pathway ENSG00000040199 PMC4701972__F2 Regulation of the Hippo pathway by upstream signals ENSG00000186575 ENSG00000149930 ENSG00000160551 ENSG00000135090 ENSG00000163914 ENSG00000150457 ENSG00000131023 PMC6259838__F1 Cell cycle pathway represented in KEGG ENSG00000145604 ENSG00000094804 ENSG00000118007 ENSG00000101972 ENSG00000108055 ENSG00000132646 ENSG00000135336 ENSG00000123374 ENSG00000164754 ENSG00000205250 ENSG00000277273 ENSG00000276876 PMC7038792__F1 NF2/merlin signaling and potential therapeutic targets in NF2 ENSG00000142627 ENSG00000291971 ENSG00000177606 ENSG00000136997 ENSG00000026508 ENSG00000168036 ENSG00000150457 ENSG00000187772 ENSG00000146648 ENSG00000131023 ENSG00000121966 PMC4571436__F2 CXCR3 Isoforms play functional roles in seemingly opposing directions ENSG00000291971 ENSG00000138755 ENSG00000168610 ENSG00000156273 PMC3558412__F1 Diagrammatic overview of the late stages of the HIV life-cycle ENSG00000074319 ENSG00000164163 PMC7832464__F2 Progression of SARS-CoV-2 infection and inflammation ENSG00000130234 ENSG00000125538 ENSG00000085265 PMC9709483__F2 Therapeutic potential of exosomes/miRNAs in polycystic ovary syndrome induced by the alteration of circadian rhythms ENSG00000105835 ENSG00000132326 ENSG00000069667 PMC7927067__F9 STAT1 and STAT3 regulation of inflammation and growth arrest phenotypes in senescent preadipocytes ENSG00000169245 ENSG00000164430 ENSG00000187608 ENSG00000115415 ENSG00000183486 ENSG00000168610 PMC6209233__F10 Proteomic analysis of human prostate cancer PC-3M-1E8 cells and PC-3M-2B4 cells of same origin but with different metastatic potential ENSG00000169291 ENSG00000002330 ENSG00000010810 PMC9641401__F5 Krüppel-like factor 6 splice variant 1 in the development, diagnosis, and possible treatment strategies for non-small cell lung cancer ENSG00000122691 ENSG00000170558 ENSG00000106178 PMC6606851__F10 Summary of the dominant effects of WNT5A mutations on skeletal morphogenesis ENSG00000154342 ENSG00000168036 PMC3122626__F4 Key cellular signaling cascades regulating morphogenesis in C ENSG00000130234 ENSG00000166407 PMC5372601__F1 RAS/RAF/MEK aberrant signaling and mechanisms of resistance to inhibition in melanoma ENSG00000198793 ENSG00000146648 PMC4699681__F1 Signaling pathways activated in chondrocytes by fibronectin fragments ENSG00000291971 ENSG00000128342 ENSG00000166670 PMC11608501__F11 Proposed schematic describes the mechanism of TRPM7-induced pyroptosis in SE ENSG00000278718 ENSG00000162711 ENSG00000092439 ENSG00000168610 PMC3122626__F9 The calcineurin signaling pathway in C ENSG00000091704 ENSG00000101871 ENSG00000158516 ENSG00000171051 PMC8006187__F1 Network-based virus-host interaction prediction with application to SARS-CoV-2 ENSG00000069482 ENSG00000130234 PMC3589914__F5 Regulatory circuits operating in osteoblast lineage cells ENSG00000128272 ENSG00000108840 PMC9386474__F1 Oncogenic signaling pathway-related long non-coding RNAs for predicting prognosis and immunotherapy response in breast cancer ENSG00000163235 ENSG00000136997 PMC8201567__F8 Promotion effects of DEHP on hepatocellular carcinoma models: up-regulation of PD-L1 by activating the JAK2/STAT3 pathway ENSG00000168610 PMC2828057__F1 Genetic factors influencing cytarabine therapy ENSG00000167325 ENSG00000171848 ENSG00000158825 ENSG00000129187 PMC6121884__F3 Akt/mTOR pathway in schizophrenia ENSG00000177169 ENSG00000198793 ENSG00000178568 PMC7670535__F1 Role of AKAP13 in cardiac function ENSG00000081189 PMC9260392__F1 Targeting Novel Regulated Cell Death: Pyroptosis, Necroptosis, and Ferroptosis in Diabetic Retinopathy ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC3693006__F4 Molecular hydrogen regulates the expression of miR-9, miR-21 and miR-199 in LPS-activated retinal microglia cells ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC7232694__F2 Adeno-Associated Virus Genome Interactions Important for Vector Production and Transduction ENSG00000100811 ENSG00000239732 ENSG00000143379 ENSG00000132646 ENSG00000130997 ENSG00000185591 PMC3027599__F6 Ingenuity Pathway Analysis Network 2 depicting relationship among up-regulation Genes in SL1344 vs SB1117 infection groups at 8 hours ENSG00000104140 ENSG00000143878 ENSG00000145819 PMC3027599__F5 Ingenuity pathway Analysis network 1 depicting relationships among up-regulated genes in SB300 infection group relative to that of SB1117 infection group at 8 hours ENSG00000134339 ENSG00000154589 ENSG00000137265 ENSG00000169174 PMC5352145__F10 Genetic basis for variation in resistance to infection in the Drosophila melanogaster genetic reference panel ENSG00000110395 ENSG00000154678 ENSG00000198931 ENSG00000154134 ENSG00000130255 PMC8608404__F4 Two models for coordination between TLS and DSB Repair by REV7 ENSG00000253251 ENSG00000171984 ENSG00000122376 ENSG00000071539 PMC8608404__F3 REV7 controls pathway choice at DSBs ENSG00000012048 ENSG00000253251 ENSG00000171984 ENSG00000122376 ENSG00000071539 PMC5884111__F6 Cartoon schematic showing the mTOR signaling pathway in cells ENSG00000146648 PMC8608404__F2 REV7 Controls Pathway Choice at Stalled Replication Forks ENSG00000132646 ENSG00000164306 ENSG00000130997 ENSG00000071539 PMC3216677__F1 Proposed estrogen receptor (ER)-activated signaling pathways involved in vasodilation ENSG00000138798 ENSG00000146648 PMC3418323__F5 Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factor ENSG00000135111 ENSG00000128342 PMC3418323__F4 Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factor ENSG00000128342 ENSG00000168610 PMC3418323__F2 Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factor ENSG00000128342 ENSG00000168610 PMC7214455__F1 Taking aim with IAP antagonists at triple-negative breast cancer: a moving target no more? ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000064012 ENSG00000164305 ENSG00000285379 PMC8222712__F1 Lactylation, a Novel Metabolic Reprogramming Code: Current Status and Prospects ENSG00000158477 ENSG00000198793 ENSG00000136997 ENSG00000026508 ENSG00000118520 PMC6121884__F1 Mammalian target of rapamycin (mTOR) pathway ENSG00000177169 ENSG00000169047 ENSG00000198793 PMC9446768__F1 Browning of the white adipose tissue regulation: new insights into nutritional and metabolic relevance in health and diseases PMC8404464__F4 Network medicine in Cardiovascular Research ENSG00000111859 ENSG00000171759 ENSG00000108344 PMC3861374__F4 Mechanism of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) ENSG00000019991 ENSG00000146648 ENSG00000140443 PMC5974615__F1 Regulatory Network of ARF in Cancer Development ENSG00000135446 ENSG00000105810 PMC7947908__F5 Insights Into the Involvement of Circular RNAs in Autoimmune Diseases ENSG00000134982 PMC7947908__F4 Insights Into the Involvement of Circular RNAs in Autoimmune Diseases ENSG00000203710 ENSG00000023697 PMC8222783__F4 Resistance Mutations to BTK Inhibitors Originate From the NFKB but Not From the PI3K-RAS-MAPK Arm of the B Cell Receptor Signaling Pathway ENSG00000105369 ENSG00000157764 ENSG00000078369 ENSG00000007312 ENSG00000198793 ENSG00000010671 ENSG00000169575 ENSG00000177455 ENSG00000095585 ENSG00000010810 ENSG00000197943 ENSG00000172936 ENSG00000175104 ENSG00000198286 PMC3726443__F6 Full Transcriptome Analysis of Early Dorsoventral Patterning in Zebrafish ENSG00000281324 ENSG00000133937 ENSG00000156925 ENSG00000168036 PMC3983488__F1 Matricellular TSP1 via CD47 restricts NO-sGC-cGMP signaling ENSG00000135218 ENSG00000198053 ENSG00000291971 PMC9464960__F3 MicroRNAs in non-alcoholic fatty liver disease: Progress and perspectives ENSG00000100811 ENSG00000104856 ENSG00000187288 ENSG00000186480 ENSG00000285482 ENSG00000096717 ENSG00000115419 ENSG00000069667 PMC7284928__F2 Protein-protein connection networks among the eight genes involved in PPARG-MI signaling pathways ENSG00000117054 ENSG00000173039 ENSG00000172936 ENSG00000132170 PMC6880621__F2 NLRC5’s role in renal diseases ENSG00000159399 PMC9017576__F1 TXNIP: A Double-Edged Sword in Disease and Therapeutic Outlook ENSG00000162711 ENSG00000265972 PMC3493640__F1 Multi-omic map of the lipid-producing yeast Rhodosporidium toruloides ENSG00000157554 ENSG00000067064 ENSG00000100412 ENSG00000197429 ENSG00000146701 ENSG00000159399 ENSG00000026103 PMC3390194__F1 Personalized Medicine and Inhibition of EGFR Signaling in Lung Cancer ENSG00000163235 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC4291046__F1 Convergent signaling pathways where inflammation and metabolic signaling intersect along the CHIEF pathway ENSG00000120833 ENSG00000104365 ENSG00000198793 ENSG00000113520 PMC5078108__F1 PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma ENSG00000159224 ENSG00000002330 ENSG00000005882 PMC6021761__F3 Discovery of IDO1 inhibitors: from bench to bedside ENSG00000188676 ENSG00000106546 PMC5660707__F5 Scheme of magnesium and calcium transporters and their interaction in the AD brain ENSG00000092439 ENSG00000142192 ENSG00000125538 ENSG00000198793 ENSG00000119121 PMC11847631__F3 Expression of inflammatory mediators induced by pathogen invasion ENSG00000108691 ENSG00000172936 ENSG00000136869 PMC5660707__F2 Model describing the copper transport system and its association with AD ENSG00000173992 ENSG00000138495 ENSG00000123191 ENSG00000177556 PMC5410960__F16 Top illustration shows disruptions in normal cell survival and normal apoptosis in glioblastoma ENSG00000138798 ENSG00000198793 ENSG00000146648 ENSG00000026103 PMC8222783__F3 Resistance Mutations to BTK Inhibitors Originate From the NFKB but Not From the PI3K-RAS-MAPK Arm of the B Cell Receptor Signaling Pathway ENSG00000105369 ENSG00000157764 ENSG00000078369 ENSG00000007312 ENSG00000198793 ENSG00000010671 ENSG00000177455 ENSG00000095585 ENSG00000239732 ENSG00000010810 ENSG00000186716 ENSG00000197943 ENSG00000172936 ENSG00000175104 ENSG00000198286 PMC8684172__F2 Regulated cell death: discovery, features and implications for neurodegenerative diseases ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000091592 ENSG00000091106 PMC8222783__F1 Resistance Mutations to BTK Inhibitors Originate From the NFKB but Not From the PI3K-RAS-MAPK Arm of the B Cell Receptor Signaling Pathway ENSG00000105369 ENSG00000157764 ENSG00000078369 ENSG00000007312 ENSG00000198793 ENSG00000010671 ENSG00000177455 ENSG00000095585 ENSG00000239732 ENSG00000010810 ENSG00000186716 ENSG00000197943 ENSG00000172936 ENSG00000175104 ENSG00000198286 PMC5733868__F4 Path diagram of the nuclear factor kappa B (NFKB) signalling pathway ENSG00000104856 ENSG00000226275 ENSG00000138798 ENSG00000173039 ENSG00000113520 ENSG00000162924 PMC4926490__F1 An illustration of the genesis of exosomal aquaporin-2 (AQP2) in renal collecting duct principal cells ENSG00000167580 ENSG00000171885 PMC4058194__F8 RTK/RAS/PI(3)K signaling pathway ENSG00000120251 ENSG00000146648 PMC6032173__F3 Regulatory mechanisms of selected modifications in PPARG ENSG00000136807 ENSG00000142611 ENSG00000138032 ENSG00000132326 ENSG00000277273 ENSG00000054118 ENSG00000096717 PMC5341000__F10 Proposed scheme for the role of male sex on energy metabolism in the diabetic kidney PMC8505728__F7 Transcriptional Changes in Pulmonary Phagocyte Subsets Dictate the Outcome Following Interaction With The Fungal Pathogen Cryptococcus neoformans ENSG00000172009 PMC8505728__F6 Transcriptional Changes in Pulmonary Phagocyte Subsets Dictate the Outcome Following Interaction With The Fungal Pathogen Cryptococcus neoformans ENSG00000151490 ENSG00000116815 ENSG00000101751 ENSG00000135218 ENSG00000153283 ENSG00000081237 ENSG00000134982 ENSG00000197471 ENSG00000163599 ENSG00000038002 ENSG00000177084 ENSG00000150637 PMC8469949__F2 Actin Cytoskeleton Dynamics and Type I IFN-Mediated Immune Response: A Dangerous Liaison in Cancer? ENSG00000183735 ENSG00000088888 ENSG00000167207 ENSG00000135828 ENSG00000276561 PMC4058194__F6 In mTOR signaling pathway, there is the triplet of genes codes for proteins (orange nodes), and the pair (ATM and TP53) corresponds to interacting proteins in the cell cycle pathway (light blue nodes) ENSG00000149311 ENSG00000198793 ENSG00000146648 PMC8469949__F1 Actin Cytoskeleton Dynamics and Type I IFN-Mediated Immune Response: A Dangerous Liaison in Cancer? ENSG00000183735 ENSG00000088888 ENSG00000115415 ENSG00000172936 ENSG00000276561 ENSG00000142166 PMC3411810__F6 BRAFV600E Negatively Regulates the AKT Pathway in Melanoma Cell Lines PMC8869457__F1 Exploring the Wnt Pathway as a Therapeutic Target for Prostate Cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000173218 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC10288531__F3A Differential Pathway Expression of Antigen Processing and Presentation ENSG00000111537 ENSG00000226492 ENSG00000127022 ENSG00000273686 ENSG00000231925 PMC7922891__F10 Graphical summary of expression profiling of human lymphoblastoid cells derived from an SS patient ENSG00000110934 ENSG00000109787 PMC5985418__F1 Fibroblast growth factor-23 (FGF23) pathways ENSG00000111012 ENSG00000118972 ENSG00000126562 ENSG00000118515 ENSG00000109062 ENSG00000080166 ENSG00000274348 ENSG00000077782 PMC7863362__F4 Compared with photoautotrophy, the expression changes of photorespiration biosynthesis pathway in mixotrophy ENSG00000261701 ENSG00000172482 ENSG00000184207 PMC5053262__F1 UPRmt signal transduction pathway in mammals and worms ENSG00000125656 PMC7863362__F5 Expression changes of central carbon and energy metabolic pathways ENSG00000062485 ENSG00000167701 PMC8603450__F1 Novel perspective in pancreatic cancer therapy: Targeting ferroptosis pathway ENSG00000168003 ENSG00000148346 ENSG00000151012 ENSG00000167468 ENSG00000111684 ENSG00000087842 ENSG00000115107 ENSG00000105552 ENSG00000057663 ENSG00000079999 PMC1489534__F3 Regulation of cell wall gene expression during the cell cycle (A) and in response to external stimuli (B) ENSG00000180447 ENSG00000066336 ENSG00000130234 ENSG00000063515 PMC8603450__F2 Novel perspective in pancreatic cancer therapy: Targeting ferroptosis pathway ENSG00000148346 ENSG00000115107 PMC8223826__F1 Exosomes in diagnosis and treatment of colorectal cancer ENSG00000110651 ENSG00000010278 ENSG00000135404 PMC5912962__F1 Comprehensive Review of Genetic Factors Contributing to Head and Neck Squamous Cell Carcinoma (HNSCC) Development in Low-Risk, Non-Traditional Patients ENSG00000175054 ENSG00000187741 PMC3410226__F1 Insulin signaling pathway ENSG00000081913 ENSG00000101255 ENSG00000197594 ENSG00000132693 PMC4211543__F1 PrPCsignaling via SFKs ENSG00000291971 ENSG00000197971 ENSG00000010810 ENSG00000168036 ENSG00000146648 PMC7190874__F4 Heart analysis ENSG00000131469 ENSG00000265681 ENSG00000165030 ENSG00000105516 ENSG00000162772 ENSG00000149295 ENSG00000177455 ENSG00000197958 ENSG00000163157 ENSG00000177606 ENSG00000291631 ENSG00000274183 ENSG00000120729 ENSG00000100985 PMC7190874__F7 Kidney analysis ENSG00000140678 ENSG00000150991 ENSG00000113140 ENSG00000146678 ENSG00000169710 ENSG00000108821 ENSG00000124253 ENSG00000166147 PMC9256076__F1 Cellular metabolism in pancreatic cancer as a tool for prognosis and treatment (Review) ENSG00000135218 ENSG00000170458 ENSG00000060982 ENSG00000136997 ENSG00000175567 PMC8949121__F6 Integration of Transcriptomic and Proteomic Analyses Reveals New Insights into the Regulation of Immune Pathways in Midgut of Samia ricini upon SariNPV Infection ENSG00000281324 ENSG00000162337 ENSG00000100387 ENSG00000134982 ENSG00000113558 ENSG00000196470 PMC10288531__F2A Differential Pathway Expression of Cardiac Muscle Contraction Pathway ENSG00000041982 ENSG00000130528 ENSG00000118729 ENSG00000135605 PMC8319020__F1 Sialic acid O-acetylation: From biosynthesis to roles in health and disease ENSG00000111726 ENSG00000164414 ENSG00000110013 PMC7824874__F3 The IRF3 signaling pathway by the UPS following LPS exposure ENSG00000132109 ENSG00000169245 ENSG00000183735 ENSG00000083799 ENSG00000110042 PMC7824874__F2 Key contributions of the UPS to the regulation of the NFKB signaling pathway in response to LPS ENSG00000172936 ENSG00000136869 ENSG00000154124 ENSG00000175104 PMC4757551__F5 Tetra-O-Methyl Nordihydroguaiaretic Acid Broadly Suppresses Cancer Metabolism and Synergistically Induces Strong Anticancer Activity in Combination with Etoposide, Rapamycin and UCN-01 ENSG00000166278 ENSG00000070669 PMC2722510__F7 Proposed pathway involved in the regulation of the osteoblast F-actin cytoskeleton, based upon previous literature and the current experimental results ENSG00000152266 ENSG00000159224 PMC11646733__F1 Efficacy of Oroxylin A in ameliorating renal fibrosis with emphasis on Sirt1 activation and TGFB/Smad3 pathway modulation ENSG00000096717 ENSG00000159399 PMC3679459__F1 TRAIL apoptotic pathway ENSG00000171791 ENSG00000168040 PMC4905055__F2 Tumor metabolism provides precursors for biomacromolecule synthesis ENSG00000131473 ENSG00000073578 ENSG00000164708 ENSG00000113790 ENSG00000131828 PMC1952634__F4 Evolving biology and treatment of prostate cancer ENSG00000129214 PMC9541002__F2 LINC00467: an oncogenic long noncoding RNA ENSG00000168036 ENSG00000077463 ENSG00000170801 PMC355851__F8 Proposed model for the observed inhibitory effects of Alpha-catulin and Alpha-catenin on the activation of cyclin D1 transcription ENSG00000163914 ENSG00000168036 PMC8140599__F3 Interaction network of selected proteins with changes in their abundance in the liver of rats exposed to distress and piracetam ENSG00000157184 ENSG00000136731 ENSG00000070831 ENSG00000004864 ENSG00000134824 ENSG00000163568 ENSG00000183020 ENSG00000127022 ENSG00000099308 ENSG00000086015 ENSG00000089597 ENSG00000115317 PMC9616781__F1 Molecular Effects of Environmental Enrichment on Alzheimer’s Disease ENSG00000122194 PMC9104724__F4 Yeast as a Model to Find New Drugs and Drug Targets for VPS13-Dependent Neurodegenerative Diseases ENSG00000117906 PMC8014260__F1 Toll‐like receptors in the pathogenesis of COVID‐19 ENSG00000131323 ENSG00000175104 ENSG00000276561 PMC4479266__F8 Sry-type HMG box 18 Contributes to the differentiation of Bone Marrow-derived Mesenchymal Stem Cells to Endothelial Cells ENSG00000110799 ENSG00000203883 ENSG00000081189 PMC3618530__F8 Interleukin-1B enhances cell migration through AP-1 and NFKB pathway dependent FGF2 expression in human corneal endothelial cells ENSG00000125538 ENSG00000175104 ENSG00000115594 PMC8727820__F3 Interaction between gut microbiome and anti-tumor drug therapy ENSG00000226275 ENSG00000198793 ENSG00000168036 ENSG00000172936 ENSG00000171791 ENSG00000168610 ENSG00000135480 ENSG00000184216 PMC3253558__F1 Conserved Herpesvirus Kinases Target the DNA Damage Response Pathway and TIP60 Histone Acetyltransferase to Promote Virus Replication ENSG00000130413 ENSG00000275618 ENSG00000111581 ENSG00000281306 ENSG00000081154 ENSG00000011260 ENSG00000291625 ENSG00000186812 ENSG00000102010 ENSG00000164751 ENSG00000086827 ENSG00000198961 ENSG00000108788 ENSG00000089199 ENSG00000105146 ENSG00000136936 PMC6215106__F7 Autophagy in response to the Zearalenone–induced G2/M cell cycle arrest ENSG00000134057 ENSG00000198793 ENSG00000101224 PMC2888474__F2 Genetic Alterations in Glioblastoma Occur Frequently in 3 Cellular Signaling Pathways ENSG00000135446 ENSG00000134853 ENSG00000105810 ENSG00000118971 ENSG00000146648 ENSG00000139687 ENSG00000196712 ENSG00000198625 PMC3862694__F10 PTEN Increases Autophagy and Inhibits the Ubiquitin-Proteasome Pathway in Glioma Cells Independently of its Lipid Phosphatase Activity ENSG00000169047 PMC7015041__F8 Molecular mechanisms involved in PLAG1 regulation in OC cells ENSG00000169047 ENSG00000181690 ENSG00000140443 PMC8883486__F1 Canonical and non-canonical NFKB pathway ENSG00000104856 ENSG00000111321 PMC8330570__F7 THADA drives Golgi residency and upregulation of PD-L1 in cancer cells and provides promising target for immunotherapy ENSG00000115970 PMC6581583__F3 Inflammatory response due to the signaling cascade when HMGB-1 interacts with surface receptors TLR2/TLR4, TREM1, and RAGE ENSG00000070831 ENSG00000291971 ENSG00000134070 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC7864012__F2 One-carbon metabolism around the folate cycle, methionine cycle and trans-sulfuration pathway ENSG00000228716 ENSG00000116761 ENSG00000178445 ENSG00000116984 PMC9143066__F1 Analysis of S-Adenosylmethionine and S-Adenosylhomocysteine: Method Optimisation and Profiling in Healthy Adults upon Short-Term Dietary Intervention PMC5134889__F2 Targeting Interleukin-2-Inducible T-cell Kinase (ITK) in T-Cell Related Diseases ENSG00000291603 ENSG00000213658 ENSG00000113263 ENSG00000124181 PMC7864012__F1 Serine-glycine biosynthesis pathway ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC2233890__F4 Multiple ERK scaffold regulate growth factor and adhesion signaling ENSG00000070831 ENSG00000143761 ENSG00000134287 ENSG00000165527 PMC10879038__F4 Programmed endothelial cell death pathways ENSG00000137275 ENSG00000167468 ENSG00000198793 ENSG00000285379 PMC10879038__F3 GSK‐3B as a converging point in key signaling pathways regulating BBB integrity post‐stroke ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000107731 PMC6660834__F1 Sfrp5/Wnt Pathway: A Protective Regulatory System in Atherosclerotic Cardiovascular Disease ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000120057 ENSG00000168036 PMC10528086__F2 When You Come to a Fork in the Road, Take It: Wnt Signaling Activates Multiple Pathways through the APC/Axin/GSK-3 Complex ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC10528086__F1 When You Come to a Fork in the Road, Take It: Wnt Signaling Activates Multiple Pathways through the APC/Axin/GSK-3 Complex ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC2747034__F1 MTDH/AEG-1 promotes tumor progression through the integration of multiple signaling pathways ENSG00000188641 ENSG00000147649 ENSG00000138795 ENSG00000151632 ENSG00000136997 ENSG00000168036 ENSG00000121270 PMC7719303__F2 Inflammation and ROS ENSG00000162711 ENSG00000107562 ENSG00000137275 ENSG00000102871 ENSG00000125538 ENSG00000265972 ENSG00000168040 ENSG00000127191 ENSG00000125995 ENSG00000188747 PMC2657775__F7 Enrichment of TGF-beta signaling pathway ENSG00000111537 ENSG00000156574 PMC2657775__F6 Enrichment of Wnt signaling pathway ENSG00000087095 ENSG00000134982 ENSG00000147869 ENSG00000115718 PMC308834__F1 A representative example of a plant pathway in MetaCyc ENSG00000159224 ENSG00000172005 PMC7073720__F4 Prostaglandin biosynthetic pathway ENSG00000166278 ENSG00000148344 ENSG00000124212 PMC2657775__F9 Enrichment of Jak-STAT signaling pathway ENSG00000127445 PMC11161882__F3 Differentially regulated pathways obtained from IPA analysis A ENSG00000147642 ENSG00000140263 ENSG00000173674 ENSG00000158747 ENSG00000203883 PMC2790404__F2 Viral infection elicits a variety of antiviral cellular responses ENSG00000184995 ENSG00000164342 PMC6142689__F5 Pathway of NRF2-mediated oxidative stress response PMC6616367__F1 Tumor necrosis factor (TNF) receptor, IkappaB kinase/nuclear factor kappa B (IKK/NFKB), c-Jun N-terminal kinase (JNK), and apoptosis in hepatocellular carcinoma (HCC) development ENSG00000042832 ENSG00000137275 ENSG00000102871 ENSG00000157625 ENSG00000168040 ENSG00000127191 ENSG00000285379 PMC6142689__F3 Pathway of calcium signaling predicted by IPA ENSG00000143549 ENSG00000131196 ENSG00000163517 PMC3572677__F1 Scheme of apoptosis pathways ENSG00000168040 PMC8363758__F6 Schematic illustrating RhoA-actin-serum response factor (SRF) signalling pathway ENSG00000132326 ENSG00000179094 PMC8496250__F1 Biological Significance of Long noncoding RNAs Dysregulation and their Mechanism of Regulating Signaling Pathways in Cervical Cancer ENSG00000181274 ENSG00000134982 ENSG00000198793 ENSG00000165879 ENSG00000168036 PMC3110643__F7 Cartoon representing CsA-mediated activation of TGF B1-dependent signaling leading to epithelial-mesenchymal transition in epidermoid carcinoma cells ENSG00000170558 ENSG00000185591 PMC3101847__F1 Pathways that regulate aging PMC2552992__F9 Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease ENSG00000144848 ENSG00000196591 ENSG00000205250 PMC6348202__F2 Proteomic and Functional Analysis Reveals an Increased Chk1 Activity in Lung Cells that Contributes to Cisplatin Resistance(A) Identification of genes involved in differential cisplatin response ENSG00000149311 ENSG00000175054 ENSG00000110395 ENSG00000138798 ENSG00000163914 PMC7081792__F1 Hippo and hyperplasia – TEAD promotes mTORC1 activation post-injury ENSG00000150457 ENSG00000131023 PMC8745114__F1 B Lineage Cells in ANCA-Associated Vasculitis ENSG00000186716 ENSG00000173599 ENSG00000145321 PMC3777492__F1 IGFBP5 enters cells through its own surface receptor or by freely diffusing into the cytoplasm ENSG00000163914 ENSG00000164690 ENSG00000115461 PMC2879563__F1 Subdivision of the estrogen metabolic pathway ENSG00000213759 PMC5040721__F4 Possible antagonistic effects of obesity on myocyte signaling to accelerate muscle atrophy ENSG00000198793 ENSG00000145321 ENSG00000163884 PMC5040721__F3 Possible adverse effects of obesity on osteoclast ENSG00000102871 ENSG00000291971 ENSG00000082512 ENSG00000198793 ENSG00000121807 ENSG00000175104 ENSG00000127191 PMC5040721__F2 Possible adverse effects of obesity on osteoblasts ENSG00000152266 ENSG00000169291 ENSG00000128272 ENSG00000163430 ENSG00000167941 ENSG00000150907 ENSG00000198793 ENSG00000163914 ENSG00000145321 ENSG00000111341 ENSG00000168610 PMC9162455__F2 Down-regulation of MHC-II antigen presentation pathway by tumour cells and possible therapeutic targets ENSG00000019582 ENSG00000111537 ENSG00000005339 ENSG00000115415 ENSG00000136997 ENSG00000277263 ENSG00000168310 ENSG00000146648 PMC5133177__F1 Mitochondrial Fe–S cluster biogenesis and Isu degradation ENSG00000182511 ENSG00000137193 PMC9162455__F1 Down-regulation of MHC-I antigen processing pathway by tumour cells and possible therapeutic targets ENSG00000157837 ENSG00000159224 ENSG00000111537 ENSG00000115415 ENSG00000136997 ENSG00000273686 ENSG00000125347 ENSG00000146648 PMC7996041__F5 Temporal changes in inflammatory mitochondria-enriched microRNAs following traumatic brain injury and effects of miR-146a nanoparticle delivery ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC9441765__F3 Emerging roles of ferroptosis in glioma ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000111684 PMC8042664__F5 Schematic model ENSG00000150782 ENSG00000125538 PMC2913704__F6 TGFB1 induces Jagged1 expression in astrocytes via ALK5 and Smad3 and regulates the balance between oligodendrocyte progenitor proliferation and differentiation ENSG00000105329 ENSG00000148400 PMC9441765__F5 Emerging roles of ferroptosis in glioma ENSG00000128272 ENSG00000151012 ENSG00000106327 ENSG00000167468 PMC7764345__F1 Insulin signaling pathway; Insulin stimulates the insulin receptor (IR), leading to phosphorylation of insulin receptor substrate (IRS) ENSG00000169047 PMC4789572__F7 Circadian-disruption-induced gene expression changes in rodent mammary tissues ENSG00000149311 ENSG00000175054 ENSG00000186716 ENSG00000136997 ENSG00000123374 ENSG00000112378 ENSG00000164305 ENSG00000140743 ENSG00000026103 PMC7803292__F15 Involvement of the Akt and Kras pathway in breast cancer ENSG00000076554 ENSG00000135446 ENSG00000198793 ENSG00000102349 ENSG00000109787 PMC9600751__F4 Links between Breast and Thyroid Cancer: Hormones, Genetic Susceptibility and Medical Interventions ENSG00000102699 ENSG00000198793 ENSG00000283059 PMC9600751__F3 Links between Breast and Thyroid Cancer: Hormones, Genetic Susceptibility and Medical Interventions ENSG00000157764 ENSG00000198793 ENSG00000086991 PMC8797975__F5 Striking a balance: PIP2 and PIP3 signaling in neuronal health and disease ENSG00000117020 ENSG00000134982 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC5505746__F1 Proposed potential mechanism of MDSC-mediated T cell suppression through LILRB1/2 and HLA-G interactions ENSG00000104972 ENSG00000276051 ENSG00000118520 ENSG00000274513 ENSG00000168610 PMC7203913__F9 Arabidopsis Plastidial Glucose-6-Phosphate Transporter GPT1 is Dually Targeted to Peroxisomes via the Endoplasmic Reticulum ENSG00000197713 ENSG00000008130 ENSG00000089159 PMC5035901__F4 KEGG pathway analysis of the validated miRNAs ENSG00000132906 ENSG00000124102 ENSG00000138795 ENSG00000109320 ENSG00000115904 ENSG00000168036 ENSG00000171791 ENSG00000124762 ENSG00000197461 ENSG00000163235 ENSG00000146592 ENSG00000139687 ENSG00000140443 PMC6358521__F1 Lessons learned from the study of human inborn errors of innate immunity ENSG00000104856 ENSG00000174125 ENSG00000159128 ENSG00000187608 ENSG00000173039 ENSG00000027697 ENSG00000111321 ENSG00000150455 ENSG00000168610 ENSG00000163702 ENSG00000162594 ENSG00000096996 ENSG00000105397 ENSG00000115415 ENSG00000187554 ENSG00000186716 ENSG00000172936 ENSG00000080166 PMC7062075__F4 KEGG metabolic pathway map showing significantly differentially expressed genes within the cell cycle pathway for midgut control versus UCS ENSG00000145604 ENSG00000123374 ENSG00000205250 ENSG00000277273 PMC3769161__F7 Interleukin-17 Enhancement of the Interleukin-6 Signaling Cascade in Astrocytes ENSG00000125538 ENSG00000163702 PMC6358521__F2 Lessons learned from the study of human inborn errors of innate immunity ENSG00000213928 ENSG00000187608 ENSG00000140968 ENSG00000173039 ENSG00000276561 ENSG00000142166 ENSG00000184979 ENSG00000183735 ENSG00000239732 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC7062075__F5 KEGG metabolic pathway map showing significantly differentially expressed genes within the cytokine–cytokine receptor interaction pathway for hindgut control versus UCS ENSG00000135960 ENSG00000117400 ENSG00000281857 PMC7881328__F2 Anti–Interleukin-10 Unleashes Transcriptional Response to Leishmanial Antigens in Visceral Leishmaniasis Patients ENSG00000081041 ENSG00000100906 ENSG00000109320 ENSG00000105697 ENSG00000274736 ENSG00000171791 ENSG00000135245 ENSG00000277943 ENSG00000106546 ENSG00000245848 ENSG00000169245 ENSG00000134086 ENSG00000108691 ENSG00000111537 ENSG00000008516 ENSG00000056558 ENSG00000158825 ENSG00000026508 ENSG00000131323 ENSG00000135124 ENSG00000140464 ENSG00000115009 ENSG00000062485 PMC8516342__F8 Downregulation of microRNA‐6125 promotes colorectal cancer growth through YTHDF2‐dependent recognition of N6‐methyladenosine‐modified GSK3B ENSG00000179091 ENSG00000198492 ENSG00000100744 PMC3193242__F7 The cross-talk between IKK family members in the MyD88 signaling pathway ENSG00000183735 ENSG00000157625 ENSG00000175104 PMC3137012__F8 Hypothesis of insulin signaling pathways associated with the regulation of CIDEA and CIDEC expression in human adipocytes ENSG00000187288 PMC6271692__F5 Interactomic analysis by Ingenuity Pathway Analysis (IPA) of significant molecules ENSG00000115008 ENSG00000128016 ENSG00000105835 ENSG00000173039 ENSG00000169242 ENSG00000112715 ENSG00000168811 ENSG00000277943 ENSG00000007171 ENSG00000108691 ENSG00000115415 ENSG00000170430 ENSG00000126353 ENSG00000177519 ENSG00000112115 PMC7516013__F2 Farnesoid X receptor (FXR) regulates bile acid (BA) synthesis in a tissue-specific manner ENSG00000160867 ENSG00000167910 ENSG00000180432 PMC8269153__F3 NRF2-Related Epigenetic Modifications in Cardiac and Vascular Complications of Diabetes Mellitus ENSG00000106546 ENSG00000079999 PMC8269153__F2 NRF2-Related Epigenetic Modifications in Cardiac and Vascular Complications of Diabetes Mellitus ENSG00000096717 ENSG00000079999 ENSG00000026103 PMC8414903__F2 Ferroptosis Pathway by Ubiquitination ENSG00000168003 ENSG00000182511 ENSG00000151012 ENSG00000072274 ENSG00000110911 ENSG00000115107 PMC4808028__F9 Peritoneal and hematogenous metastases of ovarian cancer cells are both controlled by the p90RSK through a self-reinforcing cell autonomous mechanism ENSG00000049323 PMC11127239__F2 Cytotoxic effects of deoxynivalenol (DON) and mechanisms of diarrhea induction ENSG00000162711 ENSG00000001626 PMC3131835__F3 Sphingosine 1-phosphate (S1P) generation and ALI-associated single-nucleotide polymorphism (SNPs) in the S1P biosynthetic pathway ENSG00000026508 ENSG00000170989 ENSG00000213694 PMC11965322__F1 STRING PPI analyses ENSG00000133083 ENSG00000100234 ENSG00000107562 ENSG00000105329 ENSG00000197635 ENSG00000102606 ENSG00000162337 ENSG00000106025 ENSG00000174804 ENSG00000250722 ENSG00000000971 ENSG00000091879 ENSG00000089225 ENSG00000132541 ENSG00000124479 ENSG00000112739 ENSG00000128052 ENSG00000167468 ENSG00000125538 ENSG00000136869 ENSG00000037280 ENSG00000163501 ENSG00000140443 PMC3269658__F5 Differentiation pathways of CSCs ENSG00000107779 ENSG00000242689 ENSG00000198793 ENSG00000131095 ENSG00000283060 ENSG00000114315 ENSG00000125968 PMC7448569__F4 Gene expression profiles of the NF-kB signaling pathway in breast cancer ENSG00000104856 ENSG00000143799 ENSG00000242689 ENSG00000102871 ENSG00000105656 ENSG00000150455 ENSG00000127191 ENSG00000010671 ENSG00000095585 ENSG00000149311 ENSG00000226275 ENSG00000213658 ENSG00000170458 ENSG00000186716 ENSG00000131323 ENSG00000175104 PMC9520296__F2 Pyroptosis as a candidate therapeutic target for Alzheimer’s disease ENSG00000278718 ENSG00000162711 ENSG00000178573 ENSG00000125538 ENSG00000281879 ENSG00000078237 PMC8506221__F5 Schematic molecular pathway of LE regarding ICAM-1 dan E-Cadherin expression ENSG00000136869 ENSG00000106546 PMC7167284__F3 Chronic HCV replication in liver cells induces a multifaceted stress response ENSG00000130164 ENSG00000015520 ENSG00000110651 ENSG00000146648 PMC8465124__F1 Splice and Dice: Intronic microRNAs, Splicing and Cancer ENSG00000138231 ENSG00000128191 ENSG00000113360 PMC3482543__F7 Toll-Like Receptor 2-Mediated Intestinal Injury and Enteric Tumor Necrosis Factor Receptor I Contribute to Liver Fibrosis in Mice ENSG00000136869 PMC5206567__F7 The locus coeruleus (LC) pathway to cortex and its involvement in stress ENSG00000128310 ENSG00000166573 PMC6167442__F2 Detailed diagram for fatty acid and phospholipid synthesis in C ENSG00000182326 PMC2329845__F2 IPA of the genes encompassed by the conserved 166 signatures and belonging to the Wnt signal transduction pathway ENSG00000143799 ENSG00000127445 ENSG00000156076 ENSG00000125398 ENSG00000177606 ENSG00000026508 ENSG00000168036 ENSG00000168646 ENSG00000196628 PMC6782198__F7 Postreceptor adaptations of the cAMP pathway observed in response to chronic antidepressant treatment ENSG00000065989 PMC3826451__F4 Intracellular PRR signaling pathways involved in RSV and hMPV-induced gene expression ENSG00000162711 ENSG00000088888 ENSG00000167207 PMC6613384__F3 Protective effects of fibroblast growth factor 21 in cardiovascular disease ENSG00000105550 ENSG00000130234 PMC8895452__F8 RASSF1A independence and early galectin‐1 upregulation in PIK3CA‐induced hepatocarcinogenesis: new therapeutic venues ENSG00000169710 ENSG00000168610 PMC3826451__F2 Toll-Like Receptors (TLR) signaling pathway involved in RSV and hMPV-induced gene expression ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC7448569__F6 Gene expression profiles of the IL-17 signaling pathway in the breast cancer group ENSG00000105656 ENSG00000162924 ENSG00000168040 PMC7448569__F5 Gene expression profiles of the C-type lectin receptor signaling pathway in the breast cancer group ENSG00000104856 ENSG00000149308 ENSG00000083799 ENSG00000111816 PMC9326442__F4 Hypercatabolism and Anti-catabolic Therapies in the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome ENSG00000198793 ENSG00000168610 ENSG00000140443 PMC9308248__F3 Promising therapeutic effects of metformin on metabolic reprogramming of cancer-associated fibroblasts in solid tumors ENSG00000155792 ENSG00000167965 PMC9609612__F12 Therapeutic Approach of Melatonin against Omicron and Some Other Variants of SARS-CoV-2 ENSG00000150457 ENSG00000131023 PMC4708174__F1 PI3K–AKT–mTOR pathway and drug targets ENSG00000163235 ENSG00000169047 PMC3399428__F2 “Hpo signaling pathway in Mammals and the cross-talk with RASFF1A signaling.” Schematic representation of mammalian Hippo kinases cascade and interconnections between Hippo pathway and rassf1a protein signal ENSG00000186575 ENSG00000139926 ENSG00000167074 ENSG00000150457 ENSG00000131023 ENSG00000026103 PMC8039545__F7 Visualization of the differential gene regulation in PBMCs responding to A ENSG00000157554 ENSG00000162924 PMC3707895__F6 NGF-Induced Cell Differentiation and Gene Activation Is Mediated by Integrative Nuclear FGFR1 Signaling (INFS) ENSG00000077279 ENSG00000077782 PMC4394589__F6 Regulation of genes in IL1/TLR signaling pathways ENSG00000183735 ENSG00000170458 ENSG00000137033 ENSG00000172936 ENSG00000131323 ENSG00000083799 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC2645538__F5 Possible neuroprotective mechanisms of mild mitochondrial uncoupling and caloric restriction in neurodegenerative diseases ENSG00000143799 ENSG00000096717 PMC4394589__F5 Regulation of genes in the JAK/STAT signaling pathway ENSG00000236637 ENSG00000274211 ENSG00000188379 ENSG00000120833 ENSG00000159128 ENSG00000033800 ENSG00000027697 ENSG00000105639 ENSG00000196396 ENSG00000168610 ENSG00000142166 ENSG00000138378 ENSG00000105397 ENSG00000171150 ENSG00000115415 ENSG00000228083 ENSG00000233816 ENSG00000120235 ENSG00000186803 ENSG00000180008 ENSG00000120242 ENSG00000214042 PMC1876750__F2 Focal Adhesions Regulate AB Signaling & Cell Death in Alzheimer’s Disease ENSG00000171634 ENSG00000079999 PMC3523565__F1 Simplified scheme of the mitogen-activated protein kinase (MAPK) (RAS-RAF-MEK-ERK) signaling pathway.Notes:BRAF and NRAS are the most commonly mutated oncogenes in melanoma ENSG00000157764 ENSG00000198793 ENSG00000140443 PMC4222988__F3 A) Compensatory over-activation of signal transduction pathways induced by dual PI3K/mTOR inhibitors ENSG00000171105 ENSG00000149269 ENSG00000138798 ENSG00000106070 ENSG00000169047 PMC4222988__F2 A) Compensatory over-activation of signal transduction pathways induced by rapamycin-mediated suppression of negative feedback loops ENSG00000171105 ENSG00000149269 ENSG00000138798 ENSG00000106070 ENSG00000169047 PMC7756074__F7 Proposed model of the non-genomic actions of 1,25 dihydroxyvitamin D3 (1,25 D) in the lungs infected with SARS-CoV-2 ENSG00000213928 ENSG00000115415 ENSG00000109320 PMC4222988__F1 Signaling through PI3K/mTOR and Ras/Raf/MEK/ERK pathways is controlled by negative feedback loops ENSG00000171105 ENSG00000149269 ENSG00000138798 ENSG00000106070 ENSG00000169047 ENSG00000146648 PMC7797090__F5 Metabolic pathway of glycerol and glucose bioconversion to butanol in Clostridium sp PMC8753885__F3 Identification of cardiomyopathy-related core genes through human metabolic networks and expression data ENSG00000154027 ENSG00000262785 ENSG00000142192 ENSG00000137198 ENSG00000172113 ENSG00000103024 ENSG00000254550 ENSG00000143156 ENSG00000105664 ENSG00000048392 ENSG00000164978 ENSG00000291814 ENSG00000167325 ENSG00000171848 ENSG00000119912 PMC4001054__F1 Proposed schematic models for the role of different lncRNAs (green) in neural development ENSG00000006377 ENSG00000164690 PMC5866379__F14 Cartoon showing hypothetical activation of CFTR by cigarette smoke extract via prostanoid and store-operated cAMP signaling pathways ENSG00000167323 ENSG00000001626 PMC4980531__F2 Multifaceted regulation of T cell responses by ROS ENSG00000138378 ENSG00000168610 ENSG00000026103 PMC3942790__F3 Hepcidin as therapy for primary and secondary iron overload disorders: pre-clinical models and approaches ENSG00000010704 PMC3942790__F2 Hepcidin as therapy for primary and secondary iron overload disorders: pre-clinical models and approaches ENSG00000010704 ENSG00000187045 PMC6892740__F4 Major phospholipid biosynthetic pathways, genes involved, and subcellular localization of the encoded enzymes.PTDSS1,PCYT1A, andPISD from this study (all in red font) are associated with syndromic skeletal dysplasias ENSG00000102230 ENSG00000110721 ENSG00000185813 ENSG00000100288 ENSG00000174915 ENSG00000173599 ENSG00000111666 ENSG00000134255 ENSG00000156471 ENSG00000241878 ENSG00000133027 PMC4263682__F1 An example of a cluster illustrating Ras activation ENSG00000070831 ENSG00000134982 ENSG00000140575 ENSG00000138798 ENSG00000121058 ENSG00000168036 ENSG00000146648 PMC10530945__F1 Remodeling of Tumor Microenvironment by Nanozyme Combined cGAS–STING Signaling Pathway Agonist for Enhancing Cancer Immunotherapy ENSG00000164430 PMC7307178__F8 Current model for the suppressive effect of MERS-CoV N protein on the RIG-I-induced type I/III IFN expression ENSG00000125347 ENSG00000121060 PMC2678599__F7 Filia's role in ensuring euploidy of early cleavage embryos ENSG00000087586 ENSG00000166851 PMC8194085__F1 Targeting Pyrimidine Metabolism in the Era of Precision Cancer Medicine ENSG00000158825 ENSG00000166278 ENSG00000102967 ENSG00000084774 PMC9253381__F5 Elabela Attenuates the TGFB1-Induced Epithelial-Mesenchymal Transition of Peritoneal Mesothelial Cells in Patients Receiving Peritoneal Dialysis PMC3911241__F4 Examples of network refinements and reannotations ENSG00000162882 PMC3246786__F2 The role of CYLD in canonical and noncanonical NFKB pathway ENSG00000104856 ENSG00000131323 ENSG00000083799 ENSG00000127191 PMC9265592__F1 Sphingosine-1-Phosphate (S1P) and S1P Signaling Pathway Modulators, from Current Insights to Future Perspectives ENSG00000198793 ENSG00000170989 ENSG00000180739 ENSG00000213694 ENSG00000125910 ENSG00000168610 ENSG00000267534 PMC5852471__F8 Cell cycle arrest and apoptosis induced by BOS-102 in A549 cells ENSG00000135446 PMC8851844__F8 Cluster analysis of splenocyte microRNAs in the pig reveals key signal regulators of immunomodulation in the host during acute and chronic Toxoplasma gondii infection ENSG00000104856 ENSG00000113456 ENSG00000213928 ENSG00000149308 ENSG00000083799 PMC8345935__F1 New Insights into Cancer Targeted Therapy: Nodal and Cripto-1 as Attractive Candidates ENSG00000281324 ENSG00000162337 ENSG00000291971 ENSG00000134982 ENSG00000156574 ENSG00000168036 PMC4820109__F3 Association of MicroRNA-196a2 Variant with Response to Short-Acting B2-Agonist in COPD: An Egyptian Pilot Study ENSG00000147202 ENSG00000156574 ENSG00000134853 ENSG00000067900 ENSG00000114739 PMC7485269__F4 Role of mTOR-dependent processes in NMJ alteration upon aging ENSG00000198793 PMC5080721__F4 mRNA microarray analysis (microarray cohort; n = 36 GBMs) revealed SVZ-dependent differential gene expression of key hierarchies of the Notch pathway ENSG00000188290 ENSG00000074181 ENSG00000196782 ENSG00000184916 ENSG00000090932 PMC7485269__F2 (m)TOR pathways and downstream factors and processes in fly and mammals ENSG00000177169 ENSG00000163435 ENSG00000120690 ENSG00000169047 ENSG00000145979 ENSG00000112561 ENSG00000100664 PMC7485269__F1 General organization and function of mammalian neuromuscular junction (NMJ) ENSG00000134569 ENSG00000030304 ENSG00000087085 PMC4085325__F4 SphK1/S1P/S1PR1 feed-forward loop sustain signals promoting colon tumorigenesis.Notes: SphK1 produces S1P, which is kept in the cell and/or is exported in the extracellular milieu ENSG00000170989 ENSG00000168610 ENSG00000183018 PMC11766336__F2 lncRNAs regulate the progression of malignant brain tumors ENSG00000136997 PMC8335817__F1 Interleukin‐25: New perspective and state‐of‐the‐art in cancer prognosis and treatment approaches ENSG00000102871 ENSG00000168040 ENSG00000166090 ENSG00000056736 ENSG00000175104 ENSG00000168610 ENSG00000146648 PMC4028717__F7 Triptolide sensitizes pancreatic cancer cells to TRAIL-induced activation of the Death Receptor pathway ENSG00000168040 PMC10487929__F10 Network connectivity pathway map of ACE2’s downstream effects of simulated SARS-CoV-2 infection on predicted activity of the NISP ENSG00000108691 ENSG00000111537 ENSG00000130234 ENSG00000125538 ENSG00000073756 PMC8766672__F2 Adaptive Mechanisms Make Lupin a Choice Crop for Acidic Soils Affected by Aluminum Toxicity ENSG00000129744 ENSG00000062485 PMC10487929__F11 Downstream effect analysis of molecules downstream ACE2 and upstream of the NISP in the network connectivity pathway map of ACE2’s downstream effects of simulated SARS-CoV-2 infection on predicted activity of SNCA and PD ENSG00000108691 ENSG00000125538 ENSG00000073756 PMC8194085__F3 Targeting Pyrimidine Metabolism in the Era of Precision Cancer Medicine ENSG00000157764 ENSG00000138798 ENSG00000168610 ENSG00000146648 ENSG00000102967 ENSG00000084774 PMC8894518__F1 Therapeutic progress and challenges for triple negative breast cancer: targeted therapy and immunotherapy ENSG00000167601 ENSG00000198793 ENSG00000146648 PMC8023785__F1 Emerging concepts in the science of vaccine adjuvants ENSG00000174125 ENSG00000162711 ENSG00000239732 ENSG00000164430 ENSG00000137033 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000276561 ENSG00000164342 PMC9032397__F1 Vitamin D and Ocular Diseases: A Systematic Review ENSG00000111012 ENSG00000105516 ENSG00000019186 ENSG00000186104 ENSG00000135929 PMC8894518__F3 Therapeutic progress and challenges for triple negative breast cancer: targeted therapy and immunotherapy ENSG00000128917 ENSG00000148400 ENSG00000074181 ENSG00000134982 ENSG00000168036 ENSG00000184916 ENSG00000090932 PMC4458271__F2 Role of ceramides in neuronal apoptosis ENSG00000002330 ENSG00000188690 PMC2682514__F1 Nodes with the highest relative betweenness centrality (in orange) and their interacting partners (blue) in the pancreatic cancer pathway ENSG00000146648 PMC9191826__F9 Combined treatment with anti‐PSMA CAR NK‐92 cell and anti‐PD‐L1 monoclonal antibody enhances the antitumour efficacy against castration‐resistant prostate cancer ENSG00000198793 ENSG00000231179 ENSG00000204520 PMC7488177__F2 Potential role of LRG1 in abnormal angiogenesis of diabetic nephropathy associated with TGFB1 signaling pathway ENSG00000170365 PMC3688662__F1A MODELS OF INSULIN RESISTANCE AND HEART FAILURE ENSG00000150907 ENSG00000169047 ENSG00000198793 PMC3219052__F1 SRC-3Δ4 isoform acts a signaling adaptor for EGF-dependent cancer cell migration and invasion ENSG00000138798 ENSG00000146648 PMC8984119__F1 Nutrient-Based Cellular Model to Characterize Acetylation-Dependent Protein-Protein Interactions ENSG00000131473 PMC8573113__F2 TDP-43 and ER Stress in Neurodegeneration: Friends or Foes? ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC10562563__F1 Toll-Like Receptors (TLRs) signaling pathways, intra-, and inter-signaling crosstalk circuits, and their regulatory loops ENSG00000174125 ENSG00000150455 ENSG00000183735 ENSG00000239732 ENSG00000111537 ENSG00000187554 ENSG00000157625 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC2669548__F1 Generalized schematic presentation of signaling pathways targeted by molecular therapies in malignant glioma ENSG00000198793 ENSG00000146648 PMC5525062__F2 Pathological pain and the neuroimmune interface ENSG00000162711 ENSG00000087245 ENSG00000203710 ENSG00000121807 ENSG00000186810 ENSG00000108691 ENSG00000137077 ENSG00000125538 ENSG00000189403 ENSG00000136869 ENSG00000126353 ENSG00000172936 ENSG00000100985 ENSG00000115594 PMC10136831__F3 Crosstalk between PGE2 and EGFR ENSG00000291971 ENSG00000163739 ENSG00000138798 ENSG00000146648 PMC5722817__F9 Two HEB-dependent pathways of GDT17 cell development ENSG00000111537 ENSG00000124766 ENSG00000272398 ENSG00000283060 PMC10136831__F1 Biosynthesis of prostaglandins PMC5380184__F2 Related cell process and diseases with potential disease biomarkers induced by particulate matter visualized by Pathway Studio ENSG00000137834 ENSG00000111537 ENSG00000105329 ENSG00000157601 ENSG00000271303 ENSG00000164400 ENSG00000169429 ENSG00000140465 ENSG00000023909 ENSG00000125968 ENSG00000197461 ENSG00000214253 PMC3528566__F2 Carbohydrate metabolism and ATP synthesis ENSG00000198793 ENSG00000062485 PMC2773416__F6 Diagrammatic representation of intracellular pathways that lead to the production of IL-12p40 and the mechanisms of azithromycin (AZM) to inhibit the expression of IL-12p40 upon the stimulation of LPS/IFNG ENSG00000115415 ENSG00000172936 ENSG00000175104 PMC5858703__F1 Retinoic acid-related Orphan Receptor G (RORG): connecting sterol metabolism to regulation of the immune system and autoimmune disease ENSG00000170271 ENSG00000132196 ENSG00000112972 ENSG00000001630 ENSG00000116133 ENSG00000172893 ENSG00000149809 ENSG00000109929 ENSG00000113161 ENSG00000104549 ENSG00000075239 PMC420359__F8 RA regulation of reciprocal interactions between the visceral endoderm and mesoderm that control endothelial cell growth and vascular remodeling ENSG00000112715 ENSG00000163501 PMC2440498__F1 Signaling cascades initiated via TLR2- and TLR4-dependent activation ENSG00000174125 ENSG00000183735 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC3520610__F5 Targeting the TGFB signalling pathway in disease PMC7672213__F6 Potential apoptotic pathway for anticancer effects of RPL against lung cancer ENSG00000149311 PMC5423198__F5 Visual representation of the network generated by Ingenuity Pathway Analysis (IPA) ENSG00000160789 ENSG00000140259 ENSG00000292363 ENSG00000100033 ENSG00000086758 ENSG00000092820 ENSG00000132170 ENSG00000109854 ENSG00000284320 ENSG00000144677 ENSG00000109163 ENSG00000074800 ENSG00000102878 ENSG00000133116 ENSG00000136997 ENSG00000136160 ENSG00000137573 ENSG00000139687 PMC2877979__F8 Schematic representation of some pathways and networks modified during strain improvement program according to results obtained after proteome comparison of NRRL 1951, Wis 54-1255, and AS-P-78 strains ENSG00000062485 PMC3520610__F2 Targeting the TGFB signalling pathway in disease ENSG00000163914 ENSG00000177606 ENSG00000175104 ENSG00000113360 ENSG00000076604 PMC1479345__F7 Pathway analysis ENSG00000284832 ENSG00000005893 ENSG00000136997 PMC3520610__F1 Targeting the TGFB signalling pathway in disease ENSG00000157933 ENSG00000113360 PMC9402773__F2 Wnt Signaling Pathways: A Role in Pain Processing ENSG00000134982 ENSG00000168036 PMC1479345__F6 Pathway analysis ENSG00000170608 ENSG00000130208 ENSG00000142192 ENSG00000135218 ENSG00000131668 ENSG00000158578 ENSG00000151365 ENSG00000168610 PMC1479345__F5 How dietary arachidonic- and docosahexaenoic- acid rich oils differentially affect the murine hepatic transcriptome ENSG00000004975 ENSG00000099995 ENSG00000080166 ENSG00000166851 PMC1479345__F4 Pathway analysis ENSG00000019991 ENSG00000104365 ENSG00000114349 ENSG00000172236 ENSG00000177606 ENSG00000132740 ENSG00000124253 ENSG00000010671 ENSG00000164163 PMC1479345__F3 Pathway analysis ENSG00000100811 ENSG00000130304 ENSG00000085117 ENSG00000105329 ENSG00000130522 ENSG00000177606 ENSG00000169710 ENSG00000205220 ENSG00000143333 ENSG00000103942 ENSG00000160202 PMC12192670__F2 Mechanistic network of the pleiotropic regulatory effects of the vitamin D/VDR signaling pathway in the pathophysiological microenvironment of DFUs (by Figdraw) ENSG00000196689 PMC12192670__F1 Vitamin D metabolic activation and signaling pathways (by Figdraw) ENSG00000172893 ENSG00000105516 ENSG00000135929 PMC4213374__F1 This figure illustrates some of the mechanisms by which CD40L can influence on different cell functions and the processes by which these altered cells can impact on host immunity in neoplastic diseases PMC9098154__F6 Schematic explaining the role of LINC00926 in orchestrating the regulation of WNT10B in order to regulate IFNG expression ENSG00000111537 ENSG00000169884 PMC5096382__F4 DEVELOPMENTAL CIGARETTE SMOKE EXPOSURE II: HEPATIC PROTEOME PROFILES IN 6 MONTH OLD ADULT OFFSPRING ENSG00000163631 PMC4833894__F1 Different molecules involved in the mTOR activation cascade ENSG00000169047 ENSG00000198793 PMC9520276__AF1 XBP1-mediated activation of the STING signalling pathway in macrophages contributes to liver fibrosis progression ENSG00000162711 ENSG00000164430 ENSG00000105329 PMC9487300__F7 Unravelling the progressive pathophysiology of idiopathic pulmonary fibrosis ENSG00000019991 ENSG00000113520 PMC2850399__F7 Mevalonate pathway and the pleiotropic effects of statins ENSG00000070831 ENSG00000163914 PMC4879129__F8 ASS234 targets involved in AD pathogenesis ENSG00000142192 ENSG00000002330 PMC3159104__F4 Extrinsic signal pathways for regulating pluripotency during reprogramming ENSG00000170365 ENSG00000168036 ENSG00000128342 ENSG00000168610 ENSG00000204217 PMC2832126__F1 The multi-stage autophagic process ENSG00000152348 ENSG00000110497 ENSG00000198382 ENSG00000144848 ENSG00000171791 ENSG00000145782 ENSG00000057663 PMC7695496__F2 Regulation of CH25H expression ENSG00000138135 ENSG00000136869 ENSG00000162772 ENSG00000136826 PMC7189756__F8 Downstream signaling events associated with type I interferon actions in nociceptors ENSG00000115415 ENSG00000168610 PMC3784243__F1 Role of the PD-1 Pathway in the Immune Response ENSG00000134982 PMC2785769__F7 Proposed pathways for promotion (A) and progression genes (B) influenced by TLR4 ENSG00000175264 ENSG00000152661 ENSG00000081041 ENSG00000143546 ENSG00000109321 ENSG00000113070 ENSG00000121807 ENSG00000041982 ENSG00000118785 ENSG00000124882 ENSG00000136997 ENSG00000136869 ENSG00000118520 ENSG00000146648 ENSG00000132341 PMC4175424__F2 Reactive Oxygen Species Adversely Impacts Bone Marrow Microenvironment in Diabetes ENSG00000149311 PMC9380933__F1 mRNA expression of NLRP3 and associated signalling molecules are differently regulated after SE elicited by pilocarpine or kainic acid ENSG00000162711 ENSG00000150782 ENSG00000125538 ENSG00000189403 ENSG00000136869 PMC8999182__F4 Physiological Electric Field: A Potential Construction Regulator of Human Brain Organoids ENSG00000070831 ENSG00000156299 ENSG00000163914 ENSG00000168036 ENSG00000146648 PMC6631235__F5 SAM on signal transduction pathways ENSG00000145604 PMC8556195__F1 Plasticity of pancreatic cancer stem cells: implications in therapeutic resistance ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000136997 ENSG00000026508 ENSG00000168036 ENSG00000184916 ENSG00000128602 PMC8713033__F6 Function of CARMIL1 in IL-1 Signaling ENSG00000291971 ENSG00000134070 ENSG00000172936 ENSG00000079691 ENSG00000184216 PMC9191896__F9 Pathway for sex hormone synthesis in the juvenile zebrafish ENSG00000108786 ENSG00000203857 ENSG00000176387 PMC6023969__F6 IL-37-mediated intracellular signaling cascades in eosinophils for the suppression of allergic airway inflammation ENSG00000162711 ENSG00000103490 ENSG00000163220 ENSG00000163568 ENSG00000136869 ENSG00000091106 ENSG00000164342 PMC9406959__F4 Current Opportunities for Targeting Dysregulated Neurodevelopmental Signaling Pathways in Glioblastoma ENSG00000184916 PMC9406959__F7 Current Opportunities for Targeting Dysregulated Neurodevelopmental Signaling Pathways in Glioblastoma ENSG00000111186 ENSG00000150457 ENSG00000131023 PMC3048376__F2 Training Signaling Pathway Maps to Biochemical Data with Constrained Fuzzy Logic: Quantitative Analysis of Liver Cell Responses to Inflammatory Stimuli ENSG00000163235 ENSG00000132478 ENSG00000127191 ENSG00000146648 PMC6370039__F1 Relationship between NFKB and autophagy ENSG00000100811 ENSG00000057663 PMC9406959__F2 Current Opportunities for Targeting Dysregulated Neurodevelopmental Signaling Pathways in Glioblastoma ENSG00000106571 ENSG00000166813 ENSG00000128602 PMC6370039__F5 Relationship between the overexpression of YY1 and autophagy ENSG00000100811 ENSG00000057663 ENSG00000026103 PMC3048376__F5 Training Signaling Pathway Maps to Biochemical Data with Constrained Fuzzy Logic: Quantitative Analysis of Liver Cell Responses to Inflammatory Stimuli ENSG00000163235 ENSG00000198793 ENSG00000168610 PMC8926145__F4 Emerging Role of OTUB2 in Diseases: From Cell Signaling Pathway to Physiological Function ENSG00000128602 ENSG00000277276 PMC5986142__F5 Forced differentiation in vitro leads to stress-induced activation of DNA damage response in hiPSC-derived chondrocyte-like cells ENSG00000149311 ENSG00000124102 ENSG00000175054 ENSG00000186063 ENSG00000172005 ENSG00000123374 ENSG00000164754 ENSG00000185591 ENSG00000112378 ENSG00000277273 ENSG00000167182 ENSG00000276876 PMC9406959__F8 Current Opportunities for Targeting Dysregulated Neurodevelopmental Signaling Pathways in Glioblastoma ENSG00000184254 ENSG00000138207 ENSG00000128918 ENSG00000143320 PMC6452163__F3 Classical neurotransmitters of clozapine neighborhood in A auto-layout format and B a gamut of multifunctional molecules identified by IPA core and functional analyses (see table 2) ENSG00000179097 ENSG00000101440 ENSG00000163794 ENSG00000101180 ENSG00000170893 ENSG00000178719 ENSG00000112715 PMC8926145__F3 Emerging Role of OTUB2 in Diseases: From Cell Signaling Pathway to Physiological Function ENSG00000175104 ENSG00000277276 PMC3048376__F9 Training Signaling Pathway Maps to Biochemical Data with Constrained Fuzzy Logic: Quantitative Analysis of Liver Cell Responses to Inflammatory Stimuli ENSG00000111537 ENSG00000163235 ENSG00000125538 ENSG00000198793 ENSG00000113520 ENSG00000175104 ENSG00000168610 PMC7905081__F1 Core components of the Hippo signaling pathway and their regulation in the GV and MI-stage oocyte ENSG00000126016 ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC3471227__F1 Hh pathway activation, inhibition, and mechanisms of drug resistance ENSG00000198793 ENSG00000128602 PMC3865928__F1 Citrobacter Infection and Wnt signaling ENSG00000134982 ENSG00000168036 PMC5783456__F2 Ingenuity pathway analysis network identified with differential expressed genes ENSG00000170608 ENSG00000110721 ENSG00000187569 ENSG00000198610 ENSG00000155792 ENSG00000129514 ENSG00000131910 ENSG00000168491 ENSG00000073464 ENSG00000141338 ENSG00000106927 ENSG00000065717 ENSG00000114770 ENSG00000170370 ENSG00000288369 ENSG00000198074 ENSG00000184486 PMC7377830__F2 Tomatidine-target genes associated with the top two KEGG pathways ENSG00000157764 ENSG00000281877 ENSG00000169032 PMC4170887__F2 Gene interaction networks specific to the varying doses of 60Co radiation exposure ENSG00000077150 ENSG00000132646 ENSG00000168040 ENSG00000099942 ENSG00000134046 ENSG00000106546 PMC10605613__F3 Cellular regulatory pathways involving PrPC protein in cancer ENSG00000182568 ENSG00000010810 ENSG00000100985 PMC11049334__F2 Polyphenol-target network and associated signaling pathway and biological function ENSG00000100906 ENSG00000109320 ENSG00000100985 ENSG00000073756 ENSG00000007171 PMC5654500__F3 Lost in translocation: The function of the 18 kD translocator protein ENSG00000124253 ENSG00000047932 PMC5735915__F8 The c-Myc/miR-200b-3p/PRDX2 regulatory loop ENSG00000168036 PMC9519528__F1 Neurological Consequences of Sphingosine Phosphate Lyase Insufficiency ENSG00000100422 ENSG00000147869 ENSG00000119537 PMC4782360__F3 Pathway analysis illustrating the link between PM2.5-associated miRNAs in extracellular vesicles and biological pathways related to cardiovascular disease ENSG00000107562 ENSG00000149968 ENSG00000183625 ENSG00000136696 ENSG00000136694 ENSG00000184371 ENSG00000169429 ENSG00000136697 ENSG00000162692 ENSG00000136695 ENSG00000121966 ENSG00000136688 PMC12181760__F3 Pathways linking gut‐derived metabolite TMAO to CVDs via endothelial, cardiac fibroblast and cardiomyocytes dysfunction ENSG00000162711 ENSG00000125538 ENSG00000162692 ENSG00000096717 ENSG00000142082 PMC9247141__F3 Organelle-Specific Regulations and Epigenetic Regulators in Ferroptosis ENSG00000168003 ENSG00000267673 ENSG00000135423 ENSG00000116044 ENSG00000151012 ENSG00000155287 ENSG00000197635 ENSG00000167468 ENSG00000137714 PMC9247141__F1 Organelle-Specific Regulations and Epigenetic Regulators in Ferroptosis ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000167996 ENSG00000111684 ENSG00000115107 PMC3079783__F1 Leptin Signaling in Intestinal Epithelium Mediates Resistance to Enteric Infection by Entamoeba histolytica ENSG00000002330 PMC7952990__F1 Oxidative stress leads to impaired GR function through proinflammatory signaling ENSG00000137033 ENSG00000145777 ENSG00000168610 ENSG00000106546 PMC3271643__F3 Putative mechanism of estrogen action in rat Sertoli cells ENSG00000291971 ENSG00000146648 PMC6798321__F2 Schematic presentation of Nipah virus (NiV)-induced modulation of type I interferon (IFN-I) production and signaling ENSG00000183735 ENSG00000088888 ENSG00000115415 ENSG00000107201 ENSG00000121236 ENSG00000121060 ENSG00000276561 ENSG00000164342 PMC11806010__F4 Clec9a-initiated ITAM-Syk signaling cascade and downstream pathways ENSG00000104856 ENSG00000162711 ENSG00000187796 ENSG00000197992 PMC8506081__F2 Targeting PDZ domains as potential treatment for viral infections, neurodegeneration and cancer ENSG00000151276 ENSG00000291971 ENSG00000168036 PMC7072699__F1 Metabolic pathway of sialic acids in mammalian cells ENSG00000159921 ENSG00000170191 ENSG00000162139 ENSG00000111726 ENSG00000164414 ENSG00000115488 ENSG00000095380 PMC7905011__F7 Changing cell’s redox balance (NAD +/NADH) resulting from lactate conversion to pyruvate augments reactive oxygen species (ROS) levels in differentiated C2C12 myotubes and mature skeletal muscle ENSG00000152348 ENSG00000198793 ENSG00000144848 ENSG00000145782 PMC4270131__F10 C-Terminal Module IV of Connective Tissue Growth Factor, Through EGFR/Nox1 Signaling, Activates the NFKB Pathway and Proinflammatory Factors in Vascular Smooth Muscle Cells ENSG00000146648 ENSG00000188747 PMC7285791__F4 Bioinformatics analysis of YRDC-mediated hub protein-protein interaction networks in NSCLC ENSG00000141552 ENSG00000130826 ENSG00000136718 ENSG00000242485 ENSG00000198056 ENSG00000108651 ENSG00000134057 ENSG00000185627 ENSG00000132646 ENSG00000108344 ENSG00000133119 ENSG00000144231 ENSG00000175305 PMC6536578__F10 IPA network analyses of the 40 deregulated genes that we obtained from COMPARE analysis (see ) revealed the reconstruction of (A) NFKB network pathway and (B) HIF-1A network ENSG00000265681 ENSG00000121578 ENSG00000163703 ENSG00000276464 ENSG00000204856 PMC7824851__F4 PTEN modulates cell survival and proliferation by suppressing PI3K/Akt signaling ENSG00000117020 ENSG00000198793 PMC5789353__F1 Central pathway for fatty acid and cholesterol synthesis ENSG00000131473 ENSG00000130164 ENSG00000169710 ENSG00000099194 PMC5789353__F2 Lipid Metabolism and Lipid Droplets in Pancreatic Cancer and Stellate Cells ENSG00000065833 ENSG00000079432 ENSG00000115419 PMC7712612__F3 MIR22HG is involved in signaling pathways that affect cancer progression ENSG00000124216 ENSG00000170558 ENSG00000168036 ENSG00000168610 PMC9294223__F8 Inhibition of Notch Signaling Stimulates Osteoclastogenesis From the Common Trilineage Progenitor Under Inflammatory Conditions ENSG00000143387 PMC7479660__F4 Proposed mechanism by which losartan through Hsp70 inhibits the epithelial to mesenchymal transition (EMT) induced by angiotensin II in proximal tubule cells derived from SHR ENSG00000168036 PMC6594147__F1 Dysregulated immune response in the primary mediastinal B‐cell lymphoma (PMBCL) tumour microenvironment ENSG00000104856 ENSG00000116815 ENSG00000102970 ENSG00000113520 ENSG00000162924 ENSG00000049768 PMC8247262__F5 Metabolic model of Lipomyces starkeyi for predicting lipogenesis potential from diverse low-cost substrates ENSG00000122966 ENSG00000162600 ENSG00000172005 PMC7775270__F4 Musicians in the intrinsic pathway of apoptosis—a large ensemble ENSG00000265972 ENSG00000135116 PMC6917616__F3 Metabolic and transcriptional adaption in tissue Treg cells ENSG00000137033 ENSG00000107485 ENSG00000049768 ENSG00000164120 ENSG00000106546 PMC4449706__F5 Simultaneous Inference of Cancer Pathways and Tumor Progression from Cross-Sectional Mutation Data ENSG00000121989 ENSG00000157764 ENSG00000133056 ENSG00000134982 ENSG00000105647 ENSG00000121879 ENSG00000149311 ENSG00000066468 ENSG00000125398 ENSG00000135446 ENSG00000134853 ENSG00000105810 ENSG00000077782 ENSG00000139687 ENSG00000146648 ENSG00000196712 ENSG00000198625 ENSG00000109670 PMC2667705__F7 Regulation of hepatic HNF4A expression by insulin: involvement of SREBPs and proposed liver impairments ENSG00000130164 ENSG00000113161 ENSG00000026103 PMC7930983__F3 Integrin-dependent adhesion and tensile force mechanotransduction modulate cellular behavior ENSG00000070831 PMC8318692__F2 Interleukin-17A (IL-17A): A silent amplifier of COVID-19 ENSG00000130234 ENSG00000115009 ENSG00000163702 PMC1501017__F2 Different pathways involved in apoptosis ENSG00000132906 ENSG00000120868 ENSG00000168040 ENSG00000164305 ENSG00000084774 PMC4885545__F5 Possible molecular targets whereby luteolin (Lut) inhibits the invasion of cancer cells ENSG00000019991 ENSG00000042832 ENSG00000070831 ENSG00000198793 ENSG00000112715 ENSG00000026103 PMC6538876__F1 Potential implication of proprotein convertase subtilisin/kexin type 9 (PCSK9) in amyloid B (AB) clearance in Alzheimer’s disease (AD) ENSG00000135218 ENSG00000169174 PMC5983574__F1 Invasion-related molecules in oral squamous cell carcinoma ENSG00000019991 ENSG00000186810 ENSG00000087245 ENSG00000069482 ENSG00000170558 ENSG00000138755 ENSG00000134757 ENSG00000077782 ENSG00000146648 PMC4885545__F2 Luteolin (Lut) modulates cancer cell cycle progression ENSG00000122025 ENSG00000169047 ENSG00000198793 ENSG00000197746 ENSG00000140443 PMC6331581__F5 Predicted metabolic pathways of phylotypes NkOx7-01 and NkOx7-02 ENSG00000039537 ENSG00000122218 ENSG00000145020 PMC2699904__F8 Schematic showing inter-relationships of clustered genes associated with fatty acid, lipid and lipoprotein homeostasis based on differentially-expressed genes identified in lacrimal glands of C57BL/6.NOD-Aec1Aec2 mice ENSG00000104549 ENSG00000120437 ENSG00000075239 ENSG00000168610 PMC2699904__F7 Inter-relationships of genes associated with apoptosis differentially expressed in the lacrimal glands of C57BL/6.NOD-Aec1Aec2 mice ENSG00000023445 ENSG00000110330 ENSG00000140379 ENSG00000177606 ENSG00000147133 ENSG00000169710 ENSG00000120885 ENSG00000100219 ENSG00000171791 ENSG00000258643 ENSG00000064012 PMC8212477__F4 Analysis of the transcriptome of bovine endometrial cells isolated by laser micro-dissection (2): impacts of post-partum negative energy balance on stromal, glandular and luminal epithelial cells ENSG00000122420 ENSG00000073350 ENSG00000157601 ENSG00000123104 ENSG00000160710 ENSG00000137825 ENSG00000285098 ENSG00000133019 ENSG00000105289 ENSG00000198838 ENSG00000115353 ENSG00000101333 ENSG00000109991 ENSG00000159128 ENSG00000065361 ENSG00000050628 ENSG00000115267 ENSG00000102468 ENSG00000276561 ENSG00000143375 ENSG00000108691 ENSG00000176884 ENSG00000115415 ENSG00000067606 ENSG00000183067 PMC11459742__F4 Modeling ncRNA interactions with signalling pathways using GO data ENSG00000183735 ENSG00000164430 ENSG00000172936 ENSG00000146648 PMC6730590__F2 Effects of mutant Kras in reprogramming amino acid metabolism ENSG00000125166 ENSG00000065833 ENSG00000128272 ENSG00000144895 ENSG00000070669 PMC6028121__F4 Colorectal cancer mutational profiles correlate with defined microbial communities in the tumor microenvironment ENSG00000070831 ENSG00000134982 ENSG00000168036 PMC3377831__F1 Biosynthesis and catabolism of melatonin ENSG00000165841 ENSG00000291836 ENSG00000140505 ENSG00000140465 PMC2679427__F1 Regulation of rat GSTA2 and NQO1 gene expression ENSG00000181019 ENSG00000106546 PMC3759481__F1 Simplified schematic shows the major intracellular signal transduction pathways that regulate the epithelial-to-mesenchymal transition (EMT) process in fibrotic kidneys ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6834155__F4 Non-genomic actions of thyroid hormone ENSG00000067057 ENSG00000198793 PMC6061156__F1 Ag processing and presentation pathways followed by CPP-Ag in dendritic cells PMC2921989__F1 Regulation of Energy Metabolism and the IGF-1/mTOR Pathways by the p53 Protein ENSG00000135423 ENSG00000198793 ENSG00000128342 ENSG00000078237 ENSG00000164695 PMC4776187__F3 Modes of action of lipids in enterovirus replication ENSG00000198793 PMC7522204__F5 In silico analysis indicating an inhibitory effect of Ambrisentan on PAR2 signaling pathway ENSG00000082175 ENSG00000141480 ENSG00000291971 ENSG00000146648 ENSG00000108639 PMC2921989__F2 Regulation of Energy Metabolism and the IGF-1/mTOR Pathways by the p53 Protein ENSG00000005882 PMC3209254__F9 The multiple mechanisms by which Sox2 regulates the osteoblast lineage ENSG00000168283 ENSG00000134982 ENSG00000168036 PMC12155190__F1 NFKB signalling pathway leading to the expression of genes encoding inducible nitric oxide synthase (iNOS), interleukin-6 and adhesion molecules (i ENSG00000173039 ENSG00000162692 PMC4070857__F2 The primary mechanisms through which vitamin D-regulated dendritic cells (DCs) and T-lymphocyte function.Notes: vitamin D precursors can be further processed to their active metabolite, 1,25(OH)2D3, in DCs and T lymphocytes ENSG00000111012 ENSG00000102962 ENSG00000111537 PMC7415309__F7 Long Noncoding RNA ZFPM2-AS1 Knockdown Restrains the Development of Retinoblastoma by Modulating the MicroRNA-515/HOXA1/Wnt/Beta-Catenin Axis ENSG00000105991 ENSG00000168036 PMC8693863__F7 ERK1/2 inhibition promotes robust myotube growth via CaMKII activation resulting in myoblast-to-myotube fusion ENSG00000122180 ENSG00000187616 PMC8065762__F5 Reductive stress in glutaminolysis ENSG00000115419 PMC6492945__F9 Schematic mechanism of Mac-1 regulation of human FOXP1 gene promoters and expression ENSG00000175104 ENSG00000184216 PMC12066304__F9 Genome-wide association study and transcriptomic analysis reveal the crucial role of sting1 in resistance to visceral white-nodules disease in Larimichthys polyactis ENSG00000183735 ENSG00000164430 ENSG00000276561 PMC4099309__F3 TNF and MAP kinase signaling pathways ENSG00000284161 ENSG00000167658 PMC4099309__F2 TNF and MAP kinase signaling pathways ENSG00000070831 ENSG00000102871 ENSG00000284161 ENSG00000077279 ENSG00000168040 ENSG00000127191 PMC9386726__F6 Ubiquitin-ligase TRAF6 and TGFB type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells ENSG00000087245 ENSG00000157500 ENSG00000178999 ENSG00000100985 ENSG00000175104 PMC6463562__F6 Proposed scheme for PAHSA synthesis ENSG00000131473 ENSG00000146416 ENSG00000111863 ENSG00000276559 ENSG00000008394 ENSG00000143198 ENSG00000169710 PMC2477698__F1 Examples of the molecular mechanisms by which phytochemicals activate hormetic stress response pathways ENSG00000096717 ENSG00000079999 PMC8393382__F4 Well-Known and Novel Players in Endothelial Dysfunction: Updates on a Notch(ed) Landscape ENSG00000042832 ENSG00000168036 ENSG00000132855 PMC6753107__F1 Schematic diagram of the BPV system based on a two-species microbial consortium with constrained electron flow ENSG00000173599 ENSG00000105402 PMC7795776__F5 Predicted relationship between expressed and regulated genes within integrin, paxillin, and RhoGDI signaling pathways, and the consequent activation of diseases and biological functions in elderly individuals with T2D ENSG00000070831 ENSG00000291971 ENSG00000163914 ENSG00000165527 ENSG00000089159 PMC10743408__F3 Mechanistic illustration of downregulation of interferon-responsive genes and JAK/STAT1/2 signaling pathway ENSG00000213928 ENSG00000134321 ENSG00000187608 ENSG00000105397 ENSG00000115415 ENSG00000157601 ENSG00000185745 ENSG00000125347 ENSG00000172183 ENSG00000142166 PMC12121985__F2 EGR transcription factors are essential in the functional regulation of T cells ENSG00000213658 ENSG00000122877 ENSG00000166886 PMC8619695__F4 Protein Misfolding and Aggregation: The Relatedness between Parkinson’s Disease and Hepatic Endoplasmic Reticulum Storage Disorders ENSG00000144895 ENSG00000100219 PMC7599628__F4 Initial immune response to any pathogen involves the activation of innate immunity ENSG00000174123 ENSG00000174125 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000187554 ENSG00000172936 ENSG00000136869 PMC4422811__F2 Survival signaling vs ENSG00000002330 ENSG00000138798 ENSG00000150907 ENSG00000171791 ENSG00000184481 ENSG00000146648 PMC6116115__F2 Polymerase-related genes identified using Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis ENSG00000105486 ENSG00000138346 ENSG00000132646 PMC6993408__F6 LSS-triggered VEGF-ATOH8 signal axis mediates CRC m-CTCs survival ENSG00000168874 ENSG00000159399 PMC4256275__F11 RA and FGF Signalling Are Required in the Zebrafish Otic Vesicle to Pattern and Maintain Ventral Otic Identities ENSG00000184254 PMC7528506__F1 Homologues recombinant DNA repair system ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000083093 ENSG00000051180 ENSG00000143258 ENSG00000112130 ENSG00000139618 PMC6506535__F6 T helper cell differentiation pathway of MAIT cells in comparison with conventional T cells ENSG00000162594 ENSG00000134460 ENSG00000138378 ENSG00000107485 ENSG00000103522 ENSG00000049768 ENSG00000168610 PMC2908764__F3 Molecular cues controlling the pathway choices at the Drosophila and vertebrate midline ENSG00000157404 PMC8650508__F6 Salvianolic acid B targets mortalin and inhibits the migration and invasion of hepatocellular carcinoma via the RECK/STAT3 pathway ENSG00000087245 ENSG00000170558 ENSG00000100985 ENSG00000168610 PMC6506535__F5 Natural killer cell signaling pathway of MAIT cells in comparison with conventional T cells ENSG00000291603 ENSG00000213658 PMC6506535__F4 Role of macrophage, fibroblast and endothelial cell pathways in MAIT cells ENSG00000173039 ENSG00000172936 ENSG00000111321 ENSG00000177663 ENSG00000168610 ENSG00000163702 PMC6873406__F10 Non small cell lung cancer pathway circuit ENSG00000068028 ENSG00000002330 ENSG00000138798 ENSG00000105639 ENSG00000168610 ENSG00000146648 PMC10454700__F4 Molecular Regulatory Mechanism in Multipotency and Differentiation of Wharton’s Jelly Stem Cells ENSG00000070831 PMC10454700__F3 Molecular Regulatory Mechanism in Multipotency and Differentiation of Wharton’s Jelly Stem Cells ENSG00000162337 ENSG00000168036 PMC3861057__F8 Transcriptional changes in the WNT signaling pathway of E11.5 Sost–/–; Sostdc1–/– limbs ENSG00000152661 ENSG00000154764 ENSG00000141551 ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000135341 ENSG00000118971 ENSG00000196628 ENSG00000167941 ENSG00000155011 ENSG00000136997 ENSG00000169118 ENSG00000105810 ENSG00000087095 ENSG00000154342 ENSG00000138795 ENSG00000107404 ENSG00000182968 ENSG00000140262 ENSG00000050165 ENSG00000026508 ENSG00000168646 PMC4148086__F1 Oncogenic nexus of cancerous inhibitor of protein phosphatase 2A (CIP2A): An oncoprotein with many hands ENSG00000150907 ENSG00000121058 ENSG00000168036 ENSG00000105568 ENSG00000163507 PMC12154233__F5 FSL-1 protects against radiation-induced damage through the TLR signaling pathway ENSG00000239732 ENSG00000187554 ENSG00000172936 PMC3345303__F2 Neural and Cellular Mechanisms of Fear and Extinction Memory Formation ENSG00000198793 ENSG00000198576 PMC3977151__F1 GOLGI IN COPPER HOMEOSTASIS: A VIEW FROM THE MEMBRANE TRAFFICKING FIELD ENSG00000173992 ENSG00000138495 ENSG00000123191 ENSG00000177556 PMC7144730__F5 EVO downregulates HGF-induced c-Met/Src/STAT3 phosphorylation and causes apoptosis through blocking the c-Met signaling pathway ENSG00000019991 ENSG00000291971 ENSG00000168610 PMC11591922__F3 Mechanisms by which fasting or fasting-mimicking diets kill cancer cells in solid tumors ENSG00000177169 ENSG00000123395 ENSG00000150907 ENSG00000198793 ENSG00000142082 ENSG00000140443 PMC6873406__F13 Non small cell lung cancer pathway logic circuit with miRNA ENSG00000138798 PMC6599195__F3 Signaling pathway downstream of TLR4 receptor in platelets with related cellular events and their regulatory miRNAs* ENSG00000170458 ENSG00000145321 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC4720884__F8 Hypothetical model of the signaling pathway through which MIF is involved in ConA-induced autophagic cell death of hepatoma cells ENSG00000168610 PMC5775265__F4 Differential effects of HBZ on the Jun family proteins ENSG00000280831 ENSG00000130522 ENSG00000185591 PMC7415235__F2 Key pathways involved in foam cell formation regulated by microRNA ENSG00000162711 ENSG00000135218 ENSG00000172936 ENSG00000160179 ENSG00000175104 PMC10631767__F2 Associations between CCA, TAMs and TANs ENSG00000099985 ENSG00000112715 ENSG00000168610 PMC10631767__F1 Interactions between CAFs and CCA cells ENSG00000019991 ENSG00000170962 ENSG00000113070 ENSG00000112715 ENSG00000168610 ENSG00000146648 ENSG00000121966 ENSG00000150630 PMC2713346__F1 Crz1 enters the nucleus in short stochastic bursts lasting about 2 min after undergoing dephosphorylation in the cytoplasm by the calcium-activated phosphatase calcineurin (Cn) (, ) ENSG00000157540 ENSG00000167720 ENSG00000162924 ENSG00000285485 ENSG00000131196 PMC5857600__F5 Alterations in the mammalian Hippo signaling pathway alter FLNA phosphorylation ENSG00000166341 ENSG00000150457 ENSG00000131023 ENSG00000291442 PMC6295143__F2 TREM2 molecular signaling in microglia, initiating phagocytosis and microglial survival or modulating proinflammatory response, is not well characterized so only validated components are displayed ENSG00000136869 PMC8486294__F7 CXCL5 Downregulation in Villous Tissue Is Correlated With Recurrent Spontaneous Abortion PMC4107458__F1 Neutrophil derived S100a8/S100a9 protein potentially contributing hypertensive cardiac fibrosis induced by Ang II ENSG00000143546 ENSG00000163220 ENSG00000136869 ENSG00000005381 PMC9267440__F1 Identification of Genetic Variations in the NAD-Related Pathways for Patients with Major Depressive Disorder: A Case-Control Study in Taiwan ENSG00000105835 ENSG00000118514 ENSG00000162882 ENSG00000123572 ENSG00000278488 ENSG00000183077 PMC5412052__F6 IPA generated pathway prediction for the NRF2-mediated oxidative stress response in the small intestine ENSG00000166794 ENSG00000128272 ENSG00000100906 ENSG00000177606 ENSG00000167996 ENSG00000165280 ENSG00000125656 ENSG00000176153 ENSG00000135624 ENSG00000138356 ENSG00000156273 PMC6309361__F2 Effects of hemolysis on the monocyte/macrophage compartment ENSG00000070831 ENSG00000166211 ENSG00000156273 PMC5412052__F5 Combined gene expression and predicted activation information for the mTOR pathway in the heart and small intestine ENSG00000168028 ENSG00000163435 ENSG00000171105 ENSG00000163914 ENSG00000173599 ENSG00000198911 PMC4975578__F2 Immunopathogenesis and Therapeutic Approaches in Pediatric Celiac Disease ENSG00000111537 ENSG00000164136 ENSG00000204520 ENSG00000105639 PMC6056039__F1 Calcineurin pathway in T cells and amplification of NFATc1/A ENSG00000291603 ENSG00000213658 ENSG00000178573 ENSG00000113263 ENSG00000131196 PMC4463189__F1 Targeting cancer with kinase inhibitors ENSG00000149311 ENSG00000182578 ENSG00000175054 ENSG00000157404 ENSG00000153208 ENSG00000104814 ENSG00000157764 ENSG00000149269 ENSG00000163599 ENSG00000198793 ENSG00000067900 ENSG00000285379 PMC7866294__F1 Cellular ganglioside metabolism and structure of GD2 ENSG00000069482 ENSG00000135454 ENSG00000148154 PMC4989157__F7 HIV and Cocaine Impact Glial Metabolism: Energy Sensor AMP-activated protein kinase Role in Mitochondrial Biogenesis and Epigenetic Remodeling ENSG00000117713 ENSG00000101224 PMC7006128__F6 Innate immune system pathways showing Native American ancestry enrichment ENSG00000277336 ENSG00000169245 ENSG00000239732 ENSG00000154589 ENSG00000187608 ENSG00000170458 ENSG00000163568 ENSG00000147896 ENSG00000172936 ENSG00000136869 PMC4420468__F6 Next-Generation Sequencing Analysis Reveals Differential Expression Profiles of MiRNA-mRNA Target Pairs in KSHV-Infected Cells ENSG00000148341 ENSG00000076258 ENSG00000138795 ENSG00000069869 ENSG00000102753 ENSG00000188064 ENSG00000072274 ENSG00000134070 ENSG00000128342 ENSG00000137841 ENSG00000196628 PMC11524014__F3 Carbon dots in anticancer immunotherapy ENSG00000125538 ENSG00000113851 PMC8395128__F3 Regulatory Role of microRNAs Targeting the Transcription Co-Factor ZNF521 in Normal Tissues and Cancers PMC5698910__F1 Bile acid synthesis, signaling, and regulation in human liver ENSG00000138135 ENSG00000036530 ENSG00000180432 ENSG00000267534 ENSG00000135929 PMC9322659__F8 Comparing Transcriptomes Reveals Key Metabolic Mechanisms in Superior Growth Performance Nile Tilapia (Oreochromis niloticus) ENSG00000067064 ENSG00000149084 ENSG00000172893 ENSG00000036530 ENSG00000180432 ENSG00000122787 ENSG00000120437 ENSG00000186104 PMC6158479__F2 Protective function of the calcium-sensing receptor against inflammation and carcinogenesis in the colon ENSG00000169071 ENSG00000168036 ENSG00000036828 PMC8455326__F4 Proposed gut–brain pathways mediating postoral sugar and fat appetition in mice ENSG00000197299 ENSG00000026103 PMC4632778__F10 Schema of osteogenic differentiation through the BMP signaling pathway and possible regulation by PARP activity ENSG00000170365 PMC4429004__F4 Functional prions in immune signaling ENSG00000162711 ENSG00000088888 ENSG00000174145 PMC9322659__F7 Comparing Transcriptomes Reveals Key Metabolic Mechanisms in Superior Growth Performance Nile Tilapia (Oreochromis niloticus) ENSG00000131473 ENSG00000169710 ENSG00000096717 PMC5705453__F2 The role of ASK1 in endothelial cell PMC6452649__F7 Schematic model depicting RARA’s involvement in regulation of intracellular signaling, protein synthesis, and synaptic plasticity in postsynaptic neurons PMC11547089__F10 Expression of genes involved in AsA biosynthesis in L ENSG00000100253 PMC9368002__F1 Rewiring of Glucose and Lipid Metabolism Induced by G Protein-Coupled Receptor 17 Silencing Enables the Transition of Oligodendrocyte Progenitors to Myelinating Cells ENSG00000162552 ENSG00000142192 ENSG00000107562 ENSG00000100344 ENSG00000116741 ENSG00000112715 ENSG00000064300 ENSG00000169245 ENSG00000115457 ENSG00000128052 ENSG00000197977 ENSG00000180875 ENSG00000213694 ENSG00000123983 ENSG00000067177 ENSG00000237834 PMC7482219__F1 Mesoderm patterning by a dynamic gradient of retinoic acid signalling ENSG00000095596 ENSG00000128918 ENSG00000156574 PMC11667808__F5 PI3K/AKT/mTOR, JAK/STAT3 and Rho pathway in optic nerve axon regeneration ENSG00000198793 ENSG00000163914 ENSG00000169783 ENSG00000168610 PMC8631454__F8 Dimethyl Fumarate Alleviates NLRP3 Inflammasome Activation in Microglia and Sickness Behavior in LPS-Challenged Mice ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC7911348__F1 TOR Signaling Pathway in Cardiac Aging and Heart Failure ENSG00000177169 ENSG00000155792 PMC9572851__F9 Torularhodin Alleviates Hepatic Dyslipidemia and Inflammations in High-Fat Diet-Induced Obese Mice via PPARA Signaling Pathway ENSG00000278718 ENSG00000123240 ENSG00000110244 ENSG00000105699 ENSG00000167910 ENSG00000164305 ENSG00000198721 ENSG00000005471 ENSG00000065833 ENSG00000167676 ENSG00000140284 ENSG00000158874 ENSG00000075239 ENSG00000275544 ENSG00000026103 ENSG00000171105 ENSG00000167114 ENSG00000145384 ENSG00000067900 ENSG00000168040 ENSG00000168610 ENSG00000185104 ENSG00000120899 ENSG00000073734 ENSG00000124253 ENSG00000083807 PMC5515284__F7 CanProVar 2.0: an Updated Database of Human Cancer Proteome Variation ENSG00000149311 ENSG00000175054 ENSG00000002330 ENSG00000136997 ENSG00000123374 ENSG00000112378 ENSG00000164305 ENSG00000026103 PMC7565917__F4 Hypothetical steps leading to the disassembly of NETs ENSG00000239732 ENSG00000110799 ENSG00000172936 ENSG00000136869 ENSG00000163687 PMC8507062__F3 Crucial role for the long non-coding RNA CASC11 in the pathogenesis of human cancers ENSG00000165119 ENSG00000168036 PMC5040984__F1 Patents and clinical trials involving the Wnt signaling pathway ENSG00000134982 ENSG00000168036 ENSG00000173273 PMC3930365__F6 Second ranked network of genes altered in the newborn lung at 24h post-O3 exposure ENSG00000112977 ENSG00000171320 ENSG00000100399 ENSG00000184445 ENSG00000291964 ENSG00000112578 ENSG00000129534 ENSG00000113569 ENSG00000288325 ENSG00000123219 ENSG00000086827 PMC3930365__F5 Top ranked network of genes altered in the newborn lung at 24h post-O3 exposure ENSG00000012048 ENSG00000138778 ENSG00000065911 ENSG00000148773 ENSG00000144554 ENSG00000013810 ENSG00000134982 ENSG00000280610 ENSG00000184661 ENSG00000126787 ENSG00000276043 ENSG00000093009 PMC6363221__F9 Systems biology reveals how altered TGFB signalling with age reduces protection against pro-inflammatory stimuli ENSG00000174125 ENSG00000066294 ENSG00000170365 ENSG00000173369 ENSG00000173372 ENSG00000172889 ENSG00000136869 ENSG00000184916 PMC7724003__F7 Nucleus accumbens-deep brain stimulation (NAc-DBS) alters neural excitability by modulating neuronal signaling pathways ENSG00000291507 ENSG00000143839 PMC5992605__F7 Schematic model describing the molecular responses to SIL1 loss in skeletal muscles leading to myopathy ENSG00000198793 ENSG00000116717 ENSG00000140443 PMC8201103__F7 Activation of the Integrated Stress Response and ER Stress Protect from Fluorizoline-Induced Apoptosis in HEK293T and U2OS Cell Lines ENSG00000215021 ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC8411238__F6 Combined metformin-salicylate treatment provides improved anti-tumor activity and enhanced radiotherapy response in prostate cancer; drug synergy at clinically relevant doses ENSG00000198793 PMC6521842__F9 A putative signaling pathway of ERK5/ankrd1 for promoting catecholamine biosynthesis PMC8334350__F2 Schematic models for combinatorial C. elegans and mammalian system studies regarding the role of insulin/IGF-1 signaling, mTOR pathway, and sirtuins ENSG00000012061 ENSG00000198793 ENSG00000140598 PMC5700831__F8 Depicting the possible molecular mechansims by which MitoQ prevents alcoholic liver disease through modulating ALDH2 posttranslational modifications ENSG00000086991 ENSG00000136869 PMC7118243__F2 Activation and inhibition pathways for ILC2s ENSG00000115415 ENSG00000146469 ENSG00000166090 PMC2892252__F1 Host responses to Candida albicans: Th17 cells and mucosal candidiasis ENSG00000125538 ENSG00000112115 ENSG00000168610 PMC6053273__F5 The neurogenic activity of (2R,6R)-hydroxynorketamine ENSG00000167658 ENSG00000171791 PMC6498619__F3 Evolutionary conservation of the IIS pathway ENSG00000117525 ENSG00000150907 ENSG00000184481 PMC3082642__F3 HBOT affects gene expression in the Nrf2 Pathway ENSG00000175054 ENSG00000177606 PMC5796148__F1 Change in the metabolism of adenosine signaling between the states of healthy and infected ENSG00000196839 ENSG00000110218 PMC6131422__F1 Substrates involved in caffeine biosynthesis pathways and its other related pathways catalysed by enzymes that were encoded by genes carrying the TAVs identified from this study ENSG00000159224 PMC2895966__F2 Heat Shock Protein 70 (Hsp70) as an Emerging Drug Target ENSG00000132906 ENSG00000168040 ENSG00000127191 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC7997388__F1 The human complement system ENSG00000039537 ENSG00000113600 ENSG00000134830 ENSG00000166278 ENSG00000117322 ENSG00000236625 PMC6556902__F3 Significant pathways identified using Tied Diffusion through Interacting Events method, an approach that can extract the most likely set of interconnectors between two sets of nodes ENSG00000143799 ENSG00000104884 ENSG00000134460 ENSG00000090534 ENSG00000171791 ENSG00000117400 ENSG00000164400 ENSG00000120235 ENSG00000001626 ENSG00000064012 ENSG00000162892 ENSG00000115594 ENSG00000214042 ENSG00000159128 ENSG00000137033 ENSG00000115590 ENSG00000137070 ENSG00000108342 ENSG00000115598 ENSG00000166670 ENSG00000007171 ENSG00000101082 ENSG00000111602 ENSG00000179344 ENSG00000105397 ENSG00000170458 ENSG00000172936 ENSG00000184216 ENSG00000113448 ENSG00000113494 ENSG00000110944 ENSG00000100234 ENSG00000105329 ENSG00000161405 ENSG00000164399 ENSG00000103522 ENSG00000168811 ENSG00000112715 ENSG00000137080 ENSG00000150782 ENSG00000077150 ENSG00000145623 ENSG00000276051 ENSG00000198087 ENSG00000090376 ENSG00000104432 ENSG00000115008 ENSG00000099985 ENSG00000185187 ENSG00000105639 ENSG00000115607 ENSG00000162594 ENSG00000108691 ENSG00000111537 ENSG00000145839 ENSG00000164136 ENSG00000291876 ENSG00000100985 ENSG00000073861 ENSG00000145349 ENSG00000136689 PMC3117879__F2 Implications of Relationships between Human Diseases and Metabolic Subpathways ENSG00000164362 ENSG00000171759 PMC6556902__F2 Analysis of severe asthma differential expression gene signature in the context of STRING protein association network ENSG00000186049 ENSG00000126562 ENSG00000134308 ENSG00000142733 ENSG00000073111 ENSG00000174564 ENSG00000142224 ENSG00000122025 ENSG00000150782 ENSG00000175054 ENSG00000170365 ENSG00000142677 ENSG00000088882 ENSG00000170509 ENSG00000104783 ENSG00000188157 ENSG00000125538 ENSG00000101213 ENSG00000019505 ENSG00000178078 ENSG00000170027 ENSG00000175793 ENSG00000092853 ENSG00000115590 ENSG00000183691 ENSG00000143933 ENSG00000004399 ENSG00000121774 ENSG00000170381 ENSG00000112232 ENSG00000010810 ENSG00000197299 ENSG00000165917 ENSG00000149554 ENSG00000116218 ENSG00000114739 PMC6556902__F1 Examples of representations for contextualizing disease associated genes ENSG00000179148 ENSG00000175535 ENSG00000283887 ENSG00000103490 ENSG00000161405 ENSG00000167468 ENSG00000133835 ENSG00000135966 ENSG00000116701 ENSG00000176153 ENSG00000010671 PMC12002712__F1 Biosynthetic pathway of D-tocotrienol in Y ENSG00000067064 ENSG00000197429 ENSG00000158104 PMC3595017__F1 Caspase-8 and FLIP regulate RIG-I/MDA5-induced innate immune host responses to picornaviruses ENSG00000088888 ENSG00000102871 ENSG00000168040 ENSG00000276561 PMC8397082__F1 Cardiac Neural Crest Cells in Heart Development and Congenital Heart Defects ENSG00000107779 ENSG00000177426 ENSG00000176692 ENSG00000164107 ENSG00000175826 ENSG00000164093 ENSG00000178919 PMC7553077__F2 Recent advances in engineering different immune cell types for immunotherapy applications ENSG00000089692 ENSG00000137265 ENSG00000065320 ENSG00000196092 ENSG00000273686 ENSG00000112182 PMC3309939__F8 Identification of a Novel Signaling Pathway and Its Relevance for GluA1 Recycling ENSG00000124102 ENSG00000115020 PMC8313992__F10 Acute TBK1/IKKE Inhibition Enhances the Generation of Disease-Associated Microglia-Like Phenotype Upon Cortical Stab-Wound Injury ENSG00000183735 ENSG00000111537 ENSG00000137033 ENSG00000129226 ENSG00000184371 ENSG00000183160 ENSG00000142224 PMC8353181__F3 Emerging Importance of Chemokine Receptor CXCR4 and Its Ligand in Liver Disease ENSG00000178860 ENSG00000107562 ENSG00000121966 PMC11007064__F6 Enhanced GATA4 expression in senescent systemic lupus erythematosus monocytes promotes high levels of IFNA production ENSG00000164430 ENSG00000285109 PMC7594023__F1 Pathway analysis map showing VEGF signaling via VEGFR-2 generic cascades ENSG00000162889 ENSG00000108691 ENSG00000107338 ENSG00000011422 ENSG00000070831 ENSG00000291971 ENSG00000177606 ENSG00000168036 ENSG00000067900 ENSG00000112715 ENSG00000073756 ENSG00000196628 PMC4867603__F4 Phosphoprotein network analysis of white adipose tissues unveils deregulated pathways in response to high-fat diet ENSG00000131473 ENSG00000011198 ENSG00000169710 ENSG00000131828 PMC6156233__F6 Graphical Abstract ENSG00000150782 ENSG00000197713 ENSG00000145321 ENSG00000136869 PMC8747665__F7 Preventive Effect of Anemarrhenae rhizome and Phellodendri cortex on Danazol-Induced in Precocious Puberty in Female Rats and Network Pharmacological Analysis of Active Compounds ENSG00000087245 ENSG00000171105 ENSG00000130164 ENSG00000130385 ENSG00000127948 PMC7032926__F9 Proposed model of TLR5-TLR4 interaction during environmental lung injury ENSG00000187554 ENSG00000172936 ENSG00000136869 PMC3932023__F2 Exosome secretion in a cancer cell model ENSG00000041353 ENSG00000144566 ENSG00000123595 PMC6449901__F4 Summary of genes involved in the glycolate production pathway ENSG00000112977 ENSG00000122966 ENSG00000172005 PMC3175442__F4 Map of cytoskeleton remodeling pathway (Genego Metacore, fragment) overlapped with quantile-normalized estimations of protein abundance ENSG00000106683 ENSG00000168036 ENSG00000182541 PMC8593216__F6 APE2 Is a General Regulator of the ATR-Chk1 DNA Damage Response Pathway to Maintain Genome Integrity in Pancreatic Cancer Cells ENSG00000175054 ENSG00000132646 ENSG00000164949 PMC3175442__F2 Map of pentose phosphate pathway (Genego Metacore) overlapped with quantile-normalized estimations of protein abundance ENSG00000197713 ENSG00000153574 PMC7202972__SF1 Sex steroid hormones differentially regulate CYP2D in female wild-type and CYP2D6-humanized mice ENSG00000112964 ENSG00000173757 PMC8018932__F8 Proposed model of mToxin effects in the brain of AD mice (with emphasis upon A7AChR function) ENSG00000196531 ENSG00000253506 PMC2964177__F1 ErbB2 cellular signaling pathways and lapatinib mechanism of action ENSG00000198793 PMC9095829__F8 TRP Channels as Molecular Targets to Relieve Endocrine-Related Diseases ENSG00000128272 ENSG00000100219 PMC9510782__F6 Dok3 restrains neutrophil production of calprotectin during TLR4 sensing of SARS-CoV-2 spike protein ENSG00000143546 ENSG00000146094 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC3488313__F4 Proposed mechanism of associated vWF activating GPIIb/IIIA ENSG00000110799 ENSG00000197943 PMC4812578__F1 PI3K/AKT signaling pathway ENSG00000153208 PMC7190223__F1 Components of canonical hippo signaling pathway ENSG00000150457 ENSG00000131023 PMC3259514__F1 Different signaling pathways leading to the induction of virus stress-inducible genes (VSIGs) and interferon-stimulated genes (ISGs) ENSG00000183735 ENSG00000213928 ENSG00000115415 ENSG00000125347 ENSG00000175104 ENSG00000184216 PMC6104630__F2 (B–catenin mediated) Wnt signaling pathway ENSG00000204335 ENSG00000134982 PMC4168074__F1 Model proposed by Rakoff-Nahoum et al ENSG00000172936 ENSG00000136869 PMC7047286__F4 Tdh- and tRNA synthetases-derived origins of AI-3 analogs ENSG00000198125 PMC5595144__F2 Dendritic cells (DC) can either activate adaptive immunity or tolerize T cells depending on their state of maturation ENSG00000089692 ENSG00000168610 PMC9471148__F2 An overview of agents and treatments for PDGFRA-mutated gastrointestinal stromal tumors ENSG00000157404 ENSG00000157764 ENSG00000115415 ENSG00000198793 ENSG00000134853 ENSG00000168610 ENSG00000196712 PMC4683003__F1 Acetyl-Phosphate Is Not a Global Regulatory Bridge between Virulence and Central Metabolism in Borrelia burgdorferi ENSG00000067064 ENSG00000110921 PMC7266663__F7 Strontium-substituted sub-micron bioactive glasses inhibit ostoclastogenesis through suppression of RANKL-induced signaling pathway ENSG00000090402 ENSG00000175104 ENSG00000131196 PMC8220689__F6 Circular RNAs regulate cancer-related signaling pathways and serve as potential diagnostic biomarkers for human cancers PMC8220689__F5 Circular RNAs regulate cancer-related signaling pathways and serve as potential diagnostic biomarkers for human cancers ENSG00000178585 ENSG00000168036 PMC3378042__F2 Implications of Protein Post-translational Modifications in IBD ENSG00000013374 ENSG00000136869 ENSG00000168040 PMC8529925__F1 Molecular testing for colorectal cancer: Clinical applications ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC11676931__F5 Nerelimomab alleviates capsaicin-induced acute lung injury by inhibiting the TNF signaling pathway and apoptosis in vivo and in vitro; (some of the material is from Figdraw https://www PMC7997318__F6 Nrf2 pathway in different liver diseases ENSG00000178573 ENSG00000079999 PMC9139203__F1 Molecular Characterization of BRCA1 c.5339T>C Missense Mutation in DNA Damage Response of Triple-Negative Breast Cancer ENSG00000149311 ENSG00000012048 ENSG00000083093 ENSG00000051180 ENSG00000139618 PMC5576943__F2 Complement activation pathways and allograft immunity ENSG00000291559 ENSG00000134982 ENSG00000117322 ENSG00000182326 PMC11120013__F2 Comparing Redox and Intracellular Signalling Responses to Cold Plasma in Wound Healing and Cancer ENSG00000181019 ENSG00000113070 ENSG00000138798 ENSG00000079999 PMC11120013__F4 CP-derived RONS promote cancer cell autophagy and death by activating the mitogen-activated protein kinase (MAPK) family signalling pathways ENSG00000171791 ENSG00000057663 PMC7767423__F1 Fatty acid mobilization and utilization in skeletal muscle during endurance exercise ENSG00000157184 PMC5499156__F1 Proteins that interact directly or indirectly with mGlu1/5 receptors and mediate receptor signalling ENSG00000124102 ENSG00000198793 ENSG00000161835 PMC6005849__F7 PI3K–AKT pathway perturbation in response to treatment of interleukin (IL)-6 stimulated osteoblasts with resolvin E1 (RvE1) ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000105656 ENSG00000087842 PMC10999569__F3 PIAS family in cancer: from basic mechanisms to clinical applications ENSG00000033800 PMC9170726__F8 Fas/FasL regulating mROS and IFNG production after IL-12/IL-18 stimulation ENSG00000138378 ENSG00000026103 PMC5535714__F3 Redox regulation of Wnt/Beta-catenin signaling pathway and lipid peroxidation ENSG00000134982 ENSG00000168036 PMC8466912__F3 Inhibition of Cellular and Animal Inflammatory Disease Models by NFKB Inhibitor DHMEQ ENSG00000125538 ENSG00000175104 ENSG00000127191 PMC9220248__F2 Chronic Rhinosinusitis, S. aureus Biofilm and Secreted Products, Inflammatory Responses, and Disease Severity ENSG00000137033 ENSG00000145777 ENSG00000166090 ENSG00000122194 PMC9356782__F6 Renshen Baidu Powder Attenuated Intestinal Inflammation and Apoptosis in Ulcerative Colitis Rats through the Inhibition of PI3K/AKT/NFKB Signaling Pathway ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000104894 PMC8624111__F10 Design, Synthesis and Evaluation of Novel Derivatives of Curcuminoids with Cytotoxicity ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000198793 ENSG00000136997 ENSG00000123374 ENSG00000120868 ENSG00000164305 PMC8468056__F6 GPR30 Activation by 17Beta-Estradiol Promotes p62 Phosphorylation and Increases Estrogen Receptor A Protein Expression by Inducing Its Release from a Complex Formed with KEAP1 ENSG00000291971 ENSG00000198793 ENSG00000146648 ENSG00000079999 PMC3623255__F3 Metabolic pathways in the periplasm and the cytoplasm ENSG00000118898 ENSG00000184207 PMC3623255__F2 Mass isotopomer labeling measurements of intracellular metabolites (red bars, after 8.0 h in growth phase I; green bars, after 14.25 h in growth phase II) arranged by pathways: fractional abundance over mass in context of the metabolic network ENSG00000159921 ENSG00000197713 ENSG00000172005 ENSG00000184207 PMC4350260__F1 NFKB and STAT3 in Glioblastoma: Therapeutic Targets Coming of Age ENSG00000127445 ENSG00000102871 ENSG00000198793 ENSG00000111653 ENSG00000112715 ENSG00000168610 PMC6315409__F3 Biosynthetic pathway for very-long-chain fatty acids (VLCFA), the dicarboxylic acid 20:4 (DCA 20:4), and the very-long-chain dicarboxylic acid 28:4 (VLDCA 28:4) ENSG00000118402 ENSG00000119915 ENSG00000066322 ENSG00000197977 PMC4091980__F1 Novel Inhibitors of AKT: Assessment of a Different Approach Targeting the Pleckstrin Homology Domain ENSG00000132906 ENSG00000002330 ENSG00000198793 PMC6158396__F3 HMGB1 signaling pathway in cerebrovascular disease ENSG00000125538 ENSG00000189403 PMC4280670__F3 New Cell-Signaling Pathways for Controlling Cytomegalovirus Replication ENSG00000128272 ENSG00000144895 PMC7009407__F7 Schematic and simplified diagram of some salient features of AHR signalling pathways Black solid arrows depict the canonical pathway, dashed arrows alternative pathways, and the red solid arrow an example of their intersection ENSG00000142192 ENSG00000168036 PMC9139203__F8 Molecular Characterization of BRCA1 c.5339T>C Missense Mutation in DNA Damage Response of Triple-Negative Breast Cancer ENSG00000149311 ENSG00000012048 ENSG00000083093 ENSG00000051180 ENSG00000139618 PMC3241972__F1 TOR in the immune system ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC7793734__F7 Hypothesized mechanism by which endothelial cells promote docetaxel resistance of prostate cancer cells ENSG00000157554 ENSG00000198793 ENSG00000173599 ENSG00000105656 PMC8750110__F5 Physical Forces and Transient Nuclear Envelope Rupture during Metastasis: The Key for Success? ENSG00000164430 ENSG00000197594 PMC5517472__F3 Overview of the metabolism of hepatic methylamine ENSG00000042832 ENSG00000133027 PMC7475009__F1 Based on WGCNA, we explored the correlations among gene modules and all possible variables, with particular interest in those related to age ENSG00000177455 ENSG00000186716 ENSG00000145321 ENSG00000168610 PMC4177745__F9 GLD-4-Mediated Translational Activation Regulates the Size of the Proliferative Germ Cell Pool in the Adult C. elegans Germ Line ENSG00000141034 PMC2816169__F6 Prokineticin (PROK1) induction of regulator of calcineurin 1 isoform 4 (RCAN1-4) and interleukin (IL-11) ENSG00000169618 ENSG00000159200 ENSG00000117602 ENSG00000143125 PMC10311568__F2 Research progress of sophoridine’s pharmacological activities and its molecular mechanism: an updated review ENSG00000168036 ENSG00000123374 PMC7868826__F4 EGF induced A20 expression via the MEK1/MSK1/p-p65 (Ser276) signaling pathway ENSG00000138798 PMC4280670__F1 New Cell-Signaling Pathways for Controlling Cytomegalovirus Replication ENSG00000134853 ENSG00000175104 ENSG00000146648 PMC4807283__F1 CerS are central enzymes in the sphingolipid metabolism pathway ENSG00000139624 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000119537 ENSG00000143418 PMC4344863__F1 Input overload: contributions of retinoic acid signaling feedback mechanisms to heart development and teratogenesis ENSG00000121207 ENSG00000138207 ENSG00000121039 ENSG00000128918 ENSG00000162496 ENSG00000143320 PMC6044101__F6 Spleen regulatory networks ENSG00000159224 ENSG00000138798 ENSG00000104112 ENSG00000150967 ENSG00000171791 ENSG00000278788 ENSG00000064666 ENSG00000180667 ENSG00000212935 ENSG00000109917 ENSG00000243335 ENSG00000136997 ENSG00000183032 ENSG00000197362 ENSG00000197386 ENSG00000122644 ENSG00000221890 ENSG00000144152 ENSG00000112394 ENSG00000135116 ENSG00000065802 ENSG00000181585 ENSG00000166167 ENSG00000128989 ENSG00000160058 ENSG00000171310 ENSG00000111537 ENSG00000171848 ENSG00000100479 PMC7558103__F1 The nicotinamide adenine dinucleotide (NAD) metabolism ENSG00000105835 ENSG00000278488 ENSG00000157064 ENSG00000173614 PMC4496332__F2 Dendritic spine dysgenesis in Autism Related Disorders ENSG00000159200 ENSG00000198793 ENSG00000198576 PMC10674583__F1 Nrf2-keap1/ARE signaling pathway ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC4631372__F4 Computational Characterization of Exogenous MicroRNAs that Can Be Transferred into Human Circulation ENSG00000070087 ENSG00000087095 ENSG00000104365 ENSG00000006283 ENSG00000087299 ENSG00000065559 ENSG00000091409 ENSG00000102678 ENSG00000131828 ENSG00000121966 ENSG00000145431 ENSG00000011566 ENSG00000138032 ENSG00000077782 ENSG00000083720 ENSG00000115232 ENSG00000182389 PMC4445567__F5 Upregulated and downregulated genes in the cell cycle pathway after expansion in serum-free medium ENSG00000132646 ENSG00000123374 ENSG00000166278 ENSG00000276876 PMC5681673__F4 UV-induced H1 ubiquitylation is mediated by HUWE1 and stimulates the RNF8-RNF168 pathway ENSG00000163961 ENSG00000086758 ENSG00000112130 PMC4366432__F1 Epidermal growth factor receptor pathway ENSG00000157764 ENSG00000198793 ENSG00000146648 PMC7517358__F3 Genetic networks associated with genes differentially expressed between radiosensitive and radioresistant gastric cancer (GC) cell lines ENSG00000128713 ENSG00000100234 ENSG00000125740 ENSG00000111049 ENSG00000167207 ENSG00000106123 ENSG00000162493 ENSG00000164399 ENSG00000142273 ENSG00000146457 ENSG00000137845 ENSG00000118971 ENSG00000104332 ENSG00000166886 ENSG00000188818 ENSG00000166592 ENSG00000151834 ENSG00000100290 ENSG00000008988 ENSG00000119138 ENSG00000156587 ENSG00000163993 ENSG00000189403 ENSG00000288185 ENSG00000022267 ENSG00000158427 ENSG00000283060 ENSG00000139832 ENSG00000186652 ENSG00000185247 ENSG00000136732 ENSG00000123983 ENSG00000105825 ENSG00000148346 ENSG00000175183 ENSG00000133835 ENSG00000115221 ENSG00000106100 ENSG00000166920 ENSG00000184481 ENSG00000273173 ENSG00000203747 ENSG00000019582 ENSG00000113328 ENSG00000128710 ENSG00000100934 ENSG00000148660 ENSG00000102837 PMC7403995__F7 Covid-19: The Rollercoaster of Fibrin(Ogen), D-Dimer, Von Willebrand Factor, P-Selectin and Their Interactions with Endothelial Cells, Platelets and Erythrocytes ENSG00000124102 ENSG00000213658 ENSG00000110799 ENSG00000010810 ENSG00000197943 ENSG00000010671 PMC5810588__F1 Reciprocity in ROS and autophagic signaling ENSG00000149311 ENSG00000124102 ENSG00000177169 ENSG00000152348 ENSG00000123240 ENSG00000144848 ENSG00000110931 ENSG00000112561 ENSG00000189403 ENSG00000265972 ENSG00000145782 ENSG00000057663 PMC2903791__F11 Cell signaling model for the regulation of glucose metabolism in hepatocytes by taurocholate ENSG00000291971 ENSG00000169047 ENSG00000146648 PMC4631976__F1 Death resistance signaling in cancer cells ENSG00000002330 ENSG00000137275 ENSG00000102871 ENSG00000168040 ENSG00000168404 ENSG00000285379 PMC9266893__F2 Iron, Neuroinflammation and Neurodegeneration ENSG00000010704 ENSG00000106327 ENSG00000178752 PMC2950751__F9 Summary schematic illustrating the adaptations of select genes of the IGF-1/PI3K/Akt pathway involved in protein synthesis and degradation analyzed in the plantaris muscle ENSG00000169047 ENSG00000198793 PMC4131167__F7 Differential dependency network presented over the KEGG] apoptosis pathway ENSG00000149311 ENSG00000002330 ENSG00000102871 ENSG00000164399 ENSG00000168040 ENSG00000127191 PMC4131167__F6 Rewiring of apoptosis pathway in breast cancer patients with and without recurrence ENSG00000221823 ENSG00000002330 ENSG00000109320 ENSG00000125538 ENSG00000090376 ENSG00000164305 PMC8247606__F2 Biological underpinnings of therapeutic resistance in pancreatic cancer ENSG00000065833 ENSG00000079999 PMC6291713__F8 JAK2 overexpression alleviates C2C12 myoblasts I/R injury through the AKT and ERK1/2 pathway ENSG00000111537 ENSG00000002330 ENSG00000105397 ENSG00000198793 ENSG00000171791 ENSG00000168610 PMC5997144__F2 P-Rex1 acts as a convergence point for pro-oncogenic/metastatic pathways ENSG00000113905 ENSG00000124126 ENSG00000121966 PMC11663741__F7 Protein-protein interaction networks were analyzed among differentially abundant proteins ENSG00000291603 ENSG00000187796 ENSG00000110799 ENSG00000150093 ENSG00000180644 ENSG00000122025 ENSG00000274619 ENSG00000173369 ENSG00000213949 ENSG00000166523 ENSG00000137265 ENSG00000197943 ENSG00000148357 ENSG00000133818 ENSG00000009724 ENSG00000172380 ENSG00000198561 ENSG00000007312 ENSG00000168610 ENSG00000159189 ENSG00000221823 ENSG00000141480 ENSG00000015285 ENSG00000171608 ENSG00000276838 PMC2736328__F2 Transcriptional regulation of cytokine function in airway smooth muscle cells ENSG00000102871 ENSG00000291971 ENSG00000082512 ENSG00000131323 ENSG00000127191 PMC4966762__F1 Signaling pathways activated by ET-1 in cancer ENSG00000291971 ENSG00000168036 ENSG00000146648 PMC8764238__F3 Molecular Mechanism of Puerarin Against Diabetes and its Complications ENSG00000150907 ENSG00000169047 PMC10546030__F2 Methionine biosynthesis and metabolism: Diagram of metabolic pathway showing aspartate family pathway, metabolism of methionine and cysteine biosynthesis ENSG00000095059 PMC6266939__F1 Main components of the Hippo pathway and the current Hippo-targeted inhibitors discussed in this review ENSG00000126016 ENSG00000163914 PMC8307460__F1 RelB and Neuroinflammation ENSG00000104856 ENSG00000125538 ENSG00000131323 PMC10756743__F6 Transcription Analysis of the THBS2 Gene through Regulation by Potential Noncoding Diagnostic Biomarkers and Oncogenes of Gastric Cancer in the ECM-Receptor Interaction Signaling Pathway: Integrated System Biology and Experimental Investigation ENSG00000087245 ENSG00000154736 ENSG00000186340 ENSG00000178031 ENSG00000150093 ENSG00000087116 ENSG00000151388 PMC10756743__F5 Transcription Analysis of the THBS2 Gene through Regulation by Potential Noncoding Diagnostic Biomarkers and Oncogenes of Gastric Cancer in the ECM-Receptor Interaction Signaling Pathway: Integrated System Biology and Experimental Investigation ENSG00000186340 PMC4017641__F1 O-glycan biosynthesis/human version pathway ENSG00000115339 ENSG00000285222 ENSG00000257594 ENSG00000109586 ENSG00000140297 ENSG00000136542 PMC9082421__F4 Transcriptome and iTRAQ-Based Proteome Reveal the Molecular Mechanism of Intestinal Injury Induced by Weaning Ewe's Milk in Lambs ENSG00000156738 ENSG00000072274 ENSG00000197142 ENSG00000099194 ENSG00000173391 ENSG00000140465 ENSG00000113790 ENSG00000211584 ENSG00000117322 ENSG00000138356 PMC8430316__F2 Molecular mechanisms contributing to the formation of cancer-associated adipocytes ENSG00000136997 ENSG00000168610 PMC4466442__F2 Pathologic role of TCR, BCR and TH17-induced MALT-1 in demyelination and the inhibition of this signaling pathway by A20 ENSG00000104856 ENSG00000186716 ENSG00000083799 PMC3834519__F10 FXR/NR1H4 gene ENSG00000169248 ENSG00000050730 ENSG00000108691 ENSG00000107562 ENSG00000163739 ENSG00000100985 ENSG00000090376 ENSG00000026103 PMC8764238__F1 Molecular Mechanism of Puerarin Against Diabetes and its Complications ENSG00000150907 ENSG00000168036 ENSG00000168610 PMC7277336__F1 Signaling cascade of insulin-like growth factor 1 (IGF-1) and its potential impacts in metabolism, its interactions with transforming growth factor B3 (TGFB3) and the biological functions of the IGF1, IGFBP2 and TGFß3 genes ENSG00000002330 ENSG00000169047 ENSG00000198793 ENSG00000140443 PMC8430873__F3 Cyclin Dependent Kinase-1 (CDK-1) Inhibition as a Novel Therapeutic Strategy against Pancreatic Ductal Adenocarcinoma (PDAC) ENSG00000002330 PMC9357648__F8 lncRNA XLOC013218 promotes cell proliferation and TMZ resistance by targeting the PIK3R2‐mediated PI3K/AKT pathway in glioma ENSG00000198793 ENSG00000185591 ENSG00000105647 PMC11922625__F2 Interaction of tau and DRN ENSG00000250506 PMC6122628__F2 HUWE1-mediated proliferation/differentiation ENSG00000136997 ENSG00000168036 ENSG00000164690 ENSG00000086758 ENSG00000172238 PMC3312987__F2 Commonly mutated pathways in glioblastoma ENSG00000135446 ENSG00000105810 ENSG00000196712 PMC4315039__F2 Functional components of the GDR pathway ENSG00000149311 ENSG00000175054 PMC9115588__F5 Epithelial–mesenchymal transition: The history, regulatory mechanism, and cancer therapeutic opportunities ENSG00000281324 ENSG00000162337 ENSG00000010810 ENSG00000168036 ENSG00000168610 PMC3863542__F1 UPR signaling pathways in mammalian cells ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC3812807__F7 PKCE ACTIVATION PROMOTES FGF-2 EXOCYTOSIS AND INDUCES ENDOTHELIAL CELL PROLIFERATION AND SPROUTING ENSG00000128052 ENSG00000077782 ENSG00000168610 PMC4186798__F6 Novel Compound 1, 3-bis (3, 5-dichlorophenyl) urea Inhibits Lung Cancer Progression ENSG00000134057 ENSG00000135446 ENSG00000198793 ENSG00000171791 PMC3183286__F2 The role of sphingosine kinase localization on substrate utilization and delivery of S1P to specific sites for secretion or loading of intracellular effectors ENSG00000102871 ENSG00000196591 ENSG00000127191 PMC5166441__F1 Complement system ENSG00000039537 ENSG00000113600 ENSG00000134830 ENSG00000244731 ENSG00000166278 ENSG00000132693 ENSG00000236625 PMC10987323__F10 MtETC in M2 macrophage polarization ENSG00000180210 ENSG00000135218 ENSG00000198793 ENSG00000115419 PMC6076394__F7 Network obtained from genes sharing different pathways ENSG00000140992 ENSG00000033327 ENSG00000145147 ENSG00000173156 ENSG00000138798 ENSG00000043462 ENSG00000179295 ENSG00000010810 ENSG00000115266 ENSG00000072110 ENSG00000133740 ENSG00000292357 ENSG00000162747 ENSG00000131196 PMC3666507__F4 Cross-talk between muscle (pink) and tendon (dark grey) cells in Drosophila ENSG00000168036 PMC7488355__F3 Association between Alcohol Use Disorder and manifestation of Alzheimer’s disease (AD) ENSG00000198793 PMC4900635__F7 MACC-1 Promotes Endothelium-Dependent Angiogenesis in Gastric Cancer by Activating TWIST1/VEGF-A Signal Pathway ENSG00000122691 ENSG00000145321 ENSG00000183742 ENSG00000112715 PMC6714139__F2 LPS/TLR4 signalling pathway ENSG00000183735 ENSG00000170458 ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 PMC8261291__F1 Targeting Bruton’s Tyrosine Kinase in CLL ENSG00000177455 ENSG00000095585 ENSG00000105369 ENSG00000186716 ENSG00000198793 ENSG00000197943 ENSG00000010671 PMC8882816__F3 Innate Antiviral Immune Response by Porcine Enteric Coronavirus ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000172936 ENSG00000136869 ENSG00000125347 ENSG00000168610 ENSG00000164342 PMC6961549__F1 Crosstalk between hypoxia and the unfolded protein response (UPR) pathways ENSG00000134086 ENSG00000128272 ENSG00000181788 ENSG00000198793 ENSG00000100219 PMC6531879__F4 Mapping of hits in the MAPK signaling pathway ENSG00000087095 ENSG00000172680 ENSG00000170458 ENSG00000138798 ENSG00000177606 ENSG00000130159 ENSG00000175104 ENSG00000127191 ENSG00000146648 ENSG00000026103 PMC5715835__F3 Molecular interactions and outside versus inside cell identity ENSG00000165556 ENSG00000197905 ENSG00000168036 ENSG00000107485 PMC4269892__F6 Biological and clinical significance of epigenetic silencing of MARVELD1 gene in lung cancer ENSG00000155254 ENSG00000157106 PMC11779893__F6 Possible mechanism of AMLN diet and exercise on mitochondrial homeostasis during MASLD development ENSG00000128272 ENSG00000105550 ENSG00000196365 ENSG00000125656 PMC8903056__F3 SIRT6 and epigenome maintenance ENSG00000164430 ENSG00000165392 ENSG00000077463 PMC10608708__F7 Mapping of the top targets in the PI3K-AKT signaling pathway ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000136997 PMC4774216__F1 RhoA/Rho kinase in spinal cord injury ENSG00000169783 ENSG00000198670 ENSG00000067900 PMC8623046__F9 Protection against Oxidative Stress-Induced Apoptosis by Fermented Sea Tangle (Laminaria japonica Aresch) in Osteoblastic MC3T3-E1 Cells through Activation of Nrf2 Signaling Pathway ENSG00000134363 ENSG00000079999 PMC9252758__F2 Flavonoids Targeting the mTOR Signaling Cascades in Cancer: A Potential Crosstalk in Anti-Breast Cancer Therapy ENSG00000163961 PMC4274867__F1 KEGG pathway of 470 DEGs downregulated in the frontal cortex of AD identified by RNA-Seq data analysis ENSG00000112964 ENSG00000288269 ENSG00000138039 ENSG00000102539 ENSG00000075073 ENSG00000285456 ENSG00000010310 ENSG00000004948 ENSG00000185231 ENSG00000165409 ENSG00000198670 ENSG00000121853 ENSG00000113494 PMC4691146__F2 Processes affecting TOB1 levels and diverse mechanisms underlying TOB1 tumor suppression activity ENSG00000141232 ENSG00000134982 ENSG00000168036 ENSG00000087586 ENSG00000281877 PMC4405319__F2 Toll-like receptor 4 (TLR4) signalling ENSG00000183735 ENSG00000170458 ENSG00000158485 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC6454697__F5 The relationship between zinc finger proteins and hippo pathway in cancers ENSG00000099326 PMC7812690__F4 Cardiotoxic effects of angiogenesis inhibitors ENSG00000002330 ENSG00000198793 PMC10526871__F3 Nuclear Estrogen Receptors in Prostate Cancer: From Genes to Function ENSG00000291971 ENSG00000138798 ENSG00000177606 PMC11491369__F3 Mitochondria in embryonic heart development ENSG00000116688 ENSG00000158828 ENSG00000171109 ENSG00000214253 PMC6269824__F1 Biosynthetic pathway of sialic acids and feasible implementations of artificial precursors ENSG00000159921 ENSG00000170191 ENSG00000095380 PMC6555789__F9 Summary and integration of the main results ENSG00000108839 ENSG00000179593 ENSG00000196517 PMC7058019__F2 Development of a CRISPR/Cas9n-based tool for metabolic engineering of Pseudomonas putida for ferulic acid-to-polyhydroxyalkanoate bioconversion ENSG00000168040 ENSG00000182326 PMC6615111__F3 Molecular regulators and signalling mechanisms involved in the activation of astrocytes ENSG00000182175 ENSG00000242689 ENSG00000131095 ENSG00000205927 ENSG00000128342 ENSG00000168610 PMC4324900__F4 Identification of Genetic Determinants of the Sexual Dimorphism in CNS Autoimmunity ENSG00000169291 ENSG00000275122 PMC9027032__F9 Differential Nanoscale Topography Dedicates Osteocyte-Manipulated Osteogenesis via Regulation of the TGFB Signaling Pathway ENSG00000108821 PMC7491975__F2 Different regulation of angiogenesis and vessel stability between VEGF and angiopoietin signaling, relating to regorafenib action ENSG00000291971 PMC6693777__F6 Transcriptome analysis of the molecular mechanism underlying immunity- and reproduction trade-off in Locusta migratoria infected by Micrococcus luteus ENSG00000145604 ENSG00000149311 ENSG00000171105 ENSG00000138798 ENSG00000127528 ENSG00000123374 ENSG00000176165 ENSG00000168610 ENSG00000047932 PMC3394120__F4 Cytoskeleton remodeling signaling, an example of a differentially regulated pathway in the motor cortex of SALS ENSG00000112290 ENSG00000127445 ENSG00000277586 ENSG00000100285 ENSG00000010810 ENSG00000204843 ENSG00000168036 ENSG00000173406 PMC8002322__F2 Targeted therapies directed at cell cycle and DNA damage repair pathways ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000138385 PMC4926301__F8 Angiogenin ameliorates corneal opacity and neovascularization via regulating immune response in corneal fibroblasts ENSG00000150782 ENSG00000183735 ENSG00000113520 ENSG00000172936 ENSG00000136869 PMC3223722__F1 Glycogen synthase kinase 3 modulates the function of key signaling proteins in the wnt pathway ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC11855587__F1 Endogenous Specialized Proresolving Mediators in Mast Cells and Their Involvement in Inflammation and Resolution ENSG00000134824 ENSG00000149485 ENSG00000197977 PMC5916807__F7 Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types ENSG00000166167 ENSG00000134982 ENSG00000117399 ENSG00000112130 ENSG00000145604 ENSG00000012048 ENSG00000163961 ENSG00000100387 ENSG00000136997 ENSG00000115266 ENSG00000164362 ENSG00000070950 ENSG00000004897 PMC7333221__F1 Origin of B-cell-associated malignant tumors and the anti-tumor mechanisms of HDAC6 inhibitors ENSG00000094631 ENSG00000150907 ENSG00000168036 PMC7348171__F2 Functions of NgBR include regulating cholesterol trafficking via directly binding to NPC2, hepatic FFA and TG metabolism through inhibiting LXRA transcription in an AMPKA‐dependent pathway ENSG00000042832 ENSG00000119655 ENSG00000169710 ENSG00000112715 PMC7133748__F2 Nectin adhesion pathway (positive regulation of JNK cascade) was more active in the nonresponder tumors (upper panel) than in the responder tumors (lower panel) ENSG00000006607 ENSG00000070831 ENSG00000291971 PMC10151556__F1 An update on the role of thioredoxin-interacting protein in diabetic kidney disease: A mini review ENSG00000162711 ENSG00000150907 ENSG00000125538 ENSG00000265972 PMC5314727__F4 Cell Cycle M-Phase Genes Are Highly Upregulated in Anaplastic Thyroid Carcinoma ENSG00000049323 ENSG00000019991 ENSG00000205517 ENSG00000183287 ENSG00000111859 ENSG00000138772 ENSG00000120756 ENSG00000115109 ENSG00000060982 ENSG00000154639 ENSG00000291964 ENSG00000087586 ENSG00000137807 ENSG00000138778 ENSG00000203485 ENSG00000119514 ENSG00000011422 ENSG00000145623 ENSG00000148773 ENSG00000196549 ENSG00000171241 ENSG00000171793 ENSG00000118898 ENSG00000100504 ENSG00000143179 ENSG00000180730 ENSG00000071539 ENSG00000136828 ENSG00000198932 ENSG00000181392 ENSG00000291560 ENSG00000115163 ENSG00000165891 ENSG00000100526 ENSG00000161888 ENSG00000143228 ENSG00000053372 ENSG00000122042 ENSG00000144283 ENSG00000169583 ENSG00000112984 ENSG00000006451 ENSG00000172005 ENSG00000171848 ENSG00000075218 ENSG00000168779 PMC3890716__F2 Schematic for the putative biosynthetic pathways of three major classes of active compounds in I ENSG00000197429 ENSG00000145020 ENSG00000084774 PMC11868730__F3 Drug-active components-common targets-pathways network diagram ENSG00000105854 ENSG00000171791 ENSG00000166006 ENSG00000145113 ENSG00000126218 ENSG00000112038 ENSG00000151834 ENSG00000136997 ENSG00000095303 ENSG00000275565 ENSG00000064012 ENSG00000276996 ENSG00000087245 ENSG00000197635 ENSG00000131747 ENSG00000007908 ENSG00000166670 ENSG00000102468 ENSG00000007171 ENSG00000132170 ENSG00000170961 ENSG00000138378 ENSG00000274247 ENSG00000047849 ENSG00000100591 ENSG00000152661 ENSG00000105329 ENSG00000181104 ENSG00000197408 ENSG00000140505 ENSG00000087085 ENSG00000172572 ENSG00000149294 ENSG00000168036 ENSG00000124107 ENSG00000135341 ENSG00000164305 ENSG00000158125 ENSG00000106546 ENSG00000163631 ENSG00000133019 ENSG00000117525 ENSG00000184845 ENSG00000120903 ENSG00000132906 ENSG00000011677 ENSG00000160781 ENSG00000180720 ENSG00000171105 ENSG00000104365 ENSG00000170214 ENSG00000173039 ENSG00000140465 ENSG00000073756 ENSG00000160867 ENSG00000103546 ENSG00000177606 ENSG00000057593 ENSG00000108671 ENSG00000150630 PMC5431130__F4 Representative schematic of the proposed TRIF contribution to NFKB-dependent TNFA promoter activation ENSG00000170458 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC8883581__F6 Overexpression of MUC1 Induces Non-Canonical TGFB Signaling in Pancreatic Ductal Adenocarcinoma PMC6883365__F2 Network visualization of pathways enriched with genes influencing non-platinum-based treatment response in oral cancer.Hexagon shapes are genes ENSG00000140992 ENSG00000166477 ENSG00000281324 ENSG00000117153 ENSG00000134982 ENSG00000127511 ENSG00000176533 ENSG00000230034 ENSG00000069667 ENSG00000157240 ENSG00000065717 ENSG00000171720 ENSG00000163251 ENSG00000155011 ENSG00000108375 ENSG00000197943 ENSG00000157625 ENSG00000140859 ENSG00000102910 ENSG00000162552 ENSG00000169218 ENSG00000291745 ENSG00000114450 ENSG00000136485 ENSG00000138795 ENSG00000120837 ENSG00000156076 ENSG00000042429 ENSG00000129691 ENSG00000281022 ENSG00000168938 ENSG00000132170 ENSG00000106829 ENSG00000106459 ENSG00000171016 ENSG00000175166 ENSG00000102312 ENSG00000115361 ENSG00000124659 ENSG00000066136 ENSG00000120438 ENSG00000127588 ENSG00000108344 ENSG00000188786 ENSG00000105254 ENSG00000291971 ENSG00000117500 ENSG00000110801 ENSG00000242616 ENSG00000146374 ENSG00000106546 ENSG00000150991 ENSG00000102226 ENSG00000132004 ENSG00000149269 ENSG00000285438 ENSG00000196367 ENSG00000198286 ENSG00000162188 ENSG00000127928 ENSG00000133895 ENSG00000104365 ENSG00000141556 ENSG00000182968 ENSG00000005339 ENSG00000172380 ENSG00000100906 ENSG00000213465 ENSG00000103035 ENSG00000138029 ENSG00000112335 ENSG00000111237 ENSG00000269335 ENSG00000143842 ENSG00000174804 ENSG00000069329 ENSG00000130589 ENSG00000143933 ENSG00000134595 ENSG00000175029 ENSG00000156603 ENSG00000277641 ENSG00000074219 ENSG00000172497 ENSG00000152669 ENSG00000010810 ENSG00000164362 ENSG00000055609 ENSG00000161202 ENSG00000175305 ENSG00000186469 ENSG00000173273 ENSG00000068878 PMC6883365__F1 Network visualization of pathways enriched with genes influencing platinum-based treatment response in oral cancer.Hexagon shapes are genes ENSG00000115484 ENSG00000162337 ENSG00000117153 ENSG00000134982 ENSG00000101843 ENSG00000176533 ENSG00000069667 ENSG00000065717 ENSG00000113558 ENSG00000157625 ENSG00000100211 ENSG00000102910 ENSG00000166167 ENSG00000138795 ENSG00000090104 ENSG00000108590 ENSG00000042429 ENSG00000127955 ENSG00000281022 ENSG00000141026 ENSG00000108510 ENSG00000102312 ENSG00000120438 ENSG00000127588 ENSG00000108344 ENSG00000069966 ENSG00000188786 ENSG00000175221 ENSG00000001167 ENSG00000123066 ENSG00000137177 ENSG00000291971 ENSG00000104332 ENSG00000150991 ENSG00000149269 ENSG00000183579 ENSG00000185591 ENSG00000169375 ENSG00000162188 ENSG00000182968 ENSG00000116729 ENSG00000112335 ENSG00000213465 ENSG00000103035 ENSG00000143842 ENSG00000174804 ENSG00000124766 ENSG00000130589 ENSG00000074219 ENSG00000135624 ENSG00000292120 ENSG00000110693 ENSG00000161202 ENSG00000163636 ENSG00000186469 ENSG00000173273 ENSG00000182901 ENSG00000118579 ENSG00000166477 ENSG00000063322 ENSG00000181274 ENSG00000167083 ENSG00000157240 ENSG00000114349 ENSG00000171720 ENSG00000167941 ENSG00000197943 ENSG00000177283 ENSG00000114450 ENSG00000101282 ENSG00000107404 ENSG00000118518 ENSG00000120837 ENSG00000156076 ENSG00000078369 ENSG00000129691 ENSG00000213341 ENSG00000171016 ENSG00000173992 ENSG00000175166 ENSG00000124659 ENSG00000066136 ENSG00000173692 ENSG00000105254 ENSG00000284770 ENSG00000107829 ENSG00000242616 ENSG00000146374 ENSG00000106546 ENSG00000159479 ENSG00000104371 ENSG00000184634 ENSG00000196367 ENSG00000141556 ENSG00000161920 ENSG00000104365 ENSG00000005339 ENSG00000172380 ENSG00000100906 ENSG00000173039 ENSG00000134595 ENSG00000175029 ENSG00000156603 ENSG00000101849 ENSG00000010810 ENSG00000164362 PMC6567518__F8 Summary of the function of OD-Exo in the odontogenic differentiation of DPSCs through TGFB1/smads signaling pathway via the transfer of mircoRNAs ENSG00000049323 ENSG00000105329 PMC9066101__F3 Smad3 Signatures in Renal Inflammation and Fibrosis ENSG00000135446 ENSG00000123374 ENSG00000132693 PMC9066101__F2 Smad3 Signatures in Renal Inflammation and Fibrosis ENSG00000049768 ENSG00000132693 PMC9066101__F1 Smad3 Signatures in Renal Inflammation and Fibrosis ENSG00000136807 ENSG00000168036 ENSG00000096717 ENSG00000132693 PMC316396__F7 Axial and appendicular cartilage ENSG00000285109 ENSG00000164690 ENSG00000125813 PMC6318995__F7 Characterization of complex transporter-mediated model of carbon allocation and energy supply for oil synthesis in developing P ENSG00000173599 ENSG00000172005 ENSG00000150967 ENSG00000198670 PMC7017275__F2 Identified downstream targets of YB-1 in gynecological cancer ENSG00000146648 ENSG00000121966 PMC7017275__F1 Simplistic model of the mTOR signaling pathway in cervical cancer ENSG00000106682 ENSG00000136997 ENSG00000118515 ENSG00000155792 ENSG00000146648 PMC9361070__F2 Ferroptosis, necroptosis, and pyroptosis in the occurrence and development of ovarian cancer ENSG00000115107 ENSG00000079999 PMC8829599__F5 Renal calcium and magnesium handling in Gitelman syndrome ENSG00000092439 ENSG00000169344 ENSG00000148842 ENSG00000119121 PMC9361070__F1 Ferroptosis, necroptosis, and pyroptosis in the occurrence and development of ovarian cancer ENSG00000168003 ENSG00000167468 ENSG00000111684 PMC8831326__F7 Myostatin Mutation Promotes Glycolysis by Increasing Phosphorylation of Phosphofructokinase via Activation of PDE5A-cGMP-PKG in Cattle Heart PMC9553959__F2 Transcription profiling of feline mammary carcinomas and derived cell lines reveals biomarkers and drug targets associated with metabolic and cell cycle pathways ENSG00000132906 ENSG00000175054 ENSG00000135446 ENSG00000198793 ENSG00000136997 ENSG00000042286 ENSG00000112378 ENSG00000105810 ENSG00000164305 PMC8804886__F5 mTOR inhibitors reduce enteropathy, intestinal bleeding and colectomy rate in patients with juvenile polyposis of infancy with PTEN-BMPR1A deletion ENSG00000107779 ENSG00000170365 ENSG00000137834 ENSG00000134982 ENSG00000198793 ENSG00000164327 ENSG00000283060 ENSG00000125968 PMC9553959__F4 Transcription profiling of feline mammary carcinomas and derived cell lines reveals biomarkers and drug targets associated with metabolic and cell cycle pathways ENSG00000111537 ENSG00000163131 ENSG00000127022 ENSG00000231925 PMC9553959__F3 Transcription profiling of feline mammary carcinomas and derived cell lines reveals biomarkers and drug targets associated with metabolic and cell cycle pathways ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000002330 ENSG00000069482 ENSG00000186716 ENSG00000169047 ENSG00000104894 PMC10377929__F7 Escin Activates Canonical Wnt/Beta-Catenin Signaling Pathway by Facilitating the Proteasomal Degradation of Glycogen Synthase Kinase-3B in Cultured Human Dermal Papilla Cells ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5270332__F8 Schematic diagram depicting the KRT19-mediated regulation of NUMB expression, NOTCH signaling pathway and cancer/cancer stem-like cells (CSLC) properties in KRT19-overexpressing breast cancer cells ENSG00000283780 ENSG00000148400 ENSG00000168036 ENSG00000133961 ENSG00000114315 ENSG00000171345 PMC3427211__F3 Microbes-induced EMT at the crossroad of inflammation and cancer ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000167207 ENSG00000187554 ENSG00000163568 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000106100 ENSG00000164342 PMC6454697__F4 miRNAs and Hippo pathway ENSG00000150457 ENSG00000128191 ENSG00000131023 ENSG00000113360 PMC9554999__F3 Comparison of meiotic transcriptomes of three maize inbreds with different origins reveals differences in cell cycle and recombination ENSG00000291983 ENSG00000128272 ENSG00000008952 ENSG00000198168 PMC6916696__F1 The diverse regulatory mechanisms of circRNAs in GC ENSG00000170558 ENSG00000198793 PMC8197527__F6 Carcinogenesis of Triple-Negative Breast Cancer and Sex Steroid Hormones PMC7993665__F7 Signaling pathway diagram ENSG00000278718 ENSG00000162711 ENSG00000125538 ENSG00000265972 PMC11844283__F7 Schematic model illustrating the mechanisms by which DSF/Cu activates innate immune signaling pathway to enhance anti-tumor immunity and potentiate therapeutic responses to PD-1 checkpoint blockade (created with BioRender ENSG00000169245 ENSG00000183735 ENSG00000164430 ENSG00000111537 PMC9322395__F1 Consideration of possible effects of vitamin D on established cancer, with reference to malignant melanoma ENSG00000172893 ENSG00000186104 PMC7203474__F2 Iron recycled and released by TAMs sustains the cancer progression ENSG00000148346 ENSG00000168079 PMC5352101__F3 Type I insulin-like growth factor receptor signaling in hematological malignancies ENSG00000002330 ENSG00000150907 ENSG00000169047 PMC7203474__F3 Copper addiction of cancer cells could prevent the pro-inflammatory phenotype of macrophages PMC3560469__F2 Angiotensins in the RAS ENSG00000112977 ENSG00000130234 PMC9372561__F1 Gut microbiota dysbiosis: The potential mechanisms by which alcohol disrupts gut and brain functions ENSG00000134982 ENSG00000125538 ENSG00000136869 PMC4897699__F7 Macrophage Migration Inhibitor Factor Upregulates MCP-1 Expression in an Autocrine Manner in Hepatocytes during Acute Mouse Liver Injury ENSG00000019582 ENSG00000026508 PMC4430931__F1 Signaling pathway of the extrinsic factors, glial cell line-derived neurotrophic factor (GDNF) and fibroblast growth factor 2 (FGF2) ENSG00000244405 ENSG00000150907 ENSG00000188425 ENSG00000172201 PMC8340306__F1 CGAS-STING signalling in liver diseases ENSG00000183735 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC8626953__F1 To explore immune synergistic function of Quercetin in inhibiting breast cancer cells ENSG00000115415 ENSG00000015285 PMC4417456__F4 Signaling pathways deregulated in HPV-associated HNSCC ENSG00000110330 ENSG00000142627 ENSG00000111321 ENSG00000273686 ENSG00000168040 ENSG00000066468 ENSG00000162733 ENSG00000224320 ENSG00000136997 ENSG00000131323 ENSG00000064012 ENSG00000139687 ENSG00000146648 PMC8699920__F1 Emerging Molecular Dependencies of Mutant EGFR-Driven Non-Small Cell Lung Cancer ENSG00000168610 ENSG00000146648 PMC9181319__F1 Roles of RANK/RANKL/OPG in Cardiac, Skeletal, and Smooth Muscles in Health and Disease ENSG00000082512 ENSG00000175104 ENSG00000127191 ENSG00000131196 PMC11855193__F2 ApoA-I regulates blood sugar ENSG00000169047 ENSG00000139515 PMC7397746__F1 Locations and contributions of the phosphotransferases EPT1 and CEPT1 to the biosynthesis of ethanolamine phospholipids ENSG00000198670 ENSG00000134255 PMC3584916__F3 Signaling pathway of IFIT family genes ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000276561 ENSG00000164342 PMC6520733__F6 Proposed model for ANXA2 regulation of AKT activation ENSG00000182718 ENSG00000138798 ENSG00000146648 PMC9359989__F6 Ingenuity pathway analysis of synaptosomal miRNAs in AD ENSG00000173818 ENSG00000173039 PMC7481617__F1 Estrogen receptor (ER) and pan-HER signaling inhibition has synergistic activity and leads to gene expression changes associated with good prognosis in non-small cell lung cancer (NSCLC) ENSG00000082175 ENSG00000261857 ENSG00000109321 ENSG00000138798 ENSG00000177606 ENSG00000146648 ENSG00000171604 PMC3584916__F4 Antiviral and immune regulated function of IFIT family genes ENSG00000163435 ENSG00000183735 ENSG00000152778 ENSG00000088888 ENSG00000185745 PMC7658690__F7 Relationship between target and pathway network ENSG00000177606 ENSG00000269335 ENSG00000173039 ENSG00000100985 ENSG00000073756 ENSG00000146648 PMC9303342__F2 Co‐option of stress mechanisms in the origin of evolutionary novelties ENSG00000082175 ENSG00000125384 PMC8984190__F2 Endogenous and Exogenous Regulatory Signaling in the Secretory Pathway: Role of Golgi Signaling Molecules in Cancer ENSG00000113384 ENSG00000008710 ENSG00000070831 ENSG00000291971 ENSG00000013588 PMC8984190__F1 Endogenous and Exogenous Regulatory Signaling in the Secretory Pathway: Role of Golgi Signaling Molecules in Cancer ENSG00000291971 ENSG00000013588 ENSG00000149782 ENSG00000062524 PMC9589207__F2 Non-cardiomyocytes in anticancer drug-induced cardiotoxicity: A systematic review ENSG00000198793 ENSG00000178568 PMC2756316__F5 Proposed model for the interaction between PyVmT and IR or IGF-IR ENSG00000291971 ENSG00000124181 PMC9661723__F2 Features and factors that dictate if terminating ribosomes cause or counteract nonsense-mediated mRNA decay ENSG00000198952 ENSG00000105771 ENSG00000134815 ENSG00000151461 ENSG00000070366 ENSG00000167447 ENSG00000157106 PMC6286812__F2 NOD-like receptor signaling pathway from KEGG shown with drugs, targets and known mechanism of action (→ denotes activation, ---> and ---> denote indirect effect and — denotes binding/association) ENSG00000167207 ENSG00000187796 ENSG00000137757 ENSG00000132357 ENSG00000087077 ENSG00000106100 ENSG00000108691 ENSG00000140368 ENSG00000125538 ENSG00000112851 ENSG00000157625 ENSG00000175104 ENSG00000064012 PMC8776082__F1 Interleukin-24 Immunobiology and Its Roles in Inflammatory Diseases ENSG00000142677 ENSG00000105397 ENSG00000143556 ENSG00000162892 ENSG00000174564 ENSG00000143631 PMC5854489__F3 Glaucoma as a metabolic optic neuropathy: making the case for nicotinamide treatment in glaucoma ENSG00000105835 ENSG00000172890 ENSG00000157064 ENSG00000173614 PMC6042731__F3 Cell cycle in LNCaP cells after NETD ENSG00000145604 ENSG00000094804 ENSG00000132646 ENSG00000123374 ENSG00000164754 ENSG00000091651 ENSG00000277273 ENSG00000166851 ENSG00000276876 ENSG00000093009 PMC5217522__F2 Possible explanation for opposing Notch-1 effects on NSCLC cells.Notes: Overexpression of constitutively active proteins is susceptible to experimental artifacts, the extent of which can be greatly modulated by environmental conditions ENSG00000140443 PMC8320333__F8 A New CDK4/6 and PI3K/AKT Multiple Kinase Inhibitor Aminoquinol for the Treatment of Hepatocellular Carcinoma ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC11311579__F1 Metabolic pathway of vitamin D and the role of VDR (Vitamin D Receptor) in signaling based on Płomiński et al ENSG00000172893 ENSG00000186104 ENSG00000135929 PMC6413278__F7 The proposed mechanisms for the inhibitory effects of MS-275 on osteogenesis in VICs ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000168036 PMC4218909__F2 Cartoons of PAR1 activation by thrombin in the membrane lipid-rafts of endothelial cells when EPCR is free or occupied by its natural ligand ENSG00000173599 PMC7308527__F1 Tryptophan (Trp)→ kynurenine (Kyn) metabolic pathway PMC6657359__F7 Model for Hand2-Dependent Mechanisms That Regulate iPM Formation by GHMT ENSG00000112837 ENSG00000138622 ENSG00000183072 ENSG00000164107 ENSG00000135111 ENSG00000168779 ENSG00000016082 PMC4218909__F1 Cartoons of protein C activation and APC signaling in the membrane lipid-rafts of endothelial cells ENSG00000134982 ENSG00000173599 PMC5217522__F1 Simplified schematic of Notch signaling.Notes: In mammalian cells, Notch receptors are synthesized in the endoplasmic reticulum (ER) ENSG00000140564 ENSG00000198793 ENSG00000136997 ENSG00000168036 ENSG00000140443 PMC7254680__F1 Scheme for the overall GPI-APs biosynthetic pathway, structural remodeling and transport ENSG00000135845 ENSG00000100564 ENSG00000197121 ENSG00000165282 ENSG00000275600 ENSG00000142892 ENSG00000143315 ENSG00000161395 ENSG00000108474 ENSG00000129925 ENSG00000148985 ENSG00000197858 ENSG00000136908 PMC3225910__F1 Signaling network connecting Rheb and AMPK PMC4811470__F2 Integration of tissue metabolomics, transcriptomics and immunohistochemistry reveals ERG- and gleason score-specific metabolomic alterations in prostate cancer ENSG00000198964 ENSG00000169710 ENSG00000099194 PMC4157363__F1 Determinants of Breast Cancer Progression ENSG00000128710 ENSG00000166278 ENSG00000128342 PMC3641099__F1 Gene Expression Analysis of Peripheral Blood Cells Reveals Toll-Like Receptor Pathway Deregulation in Colorectal Cancer ENSG00000108582 ENSG00000185386 PMC5384880__F5 Differential expression of proteins in the nucleus accumbens generates specific network interactomes in ENT1−/− mice ENSG00000029363 ENSG00000152661 ENSG00000078668 ENSG00000125851 ENSG00000112667 ENSG00000102109 ENSG00000187714 ENSG00000144895 ENSG00000010810 ENSG00000284099 ENSG00000175426 ENSG00000184792 ENSG00000076641 ENSG00000101327 ENSG00000112759 ENSG00000099804 ENSG00000181195 ENSG00000175104 ENSG00000154146 ENSG00000115155 ENSG00000154096 PMC5384880__F4 Differential expression of proteins in the dorsal hippocampus generates specific network interactomes in ENT1−/− mice ENSG00000142408 ENSG00000100285 ENSG00000185305 ENSG00000007237 ENSG00000122574 ENSG00000162704 ENSG00000176788 ENSG00000108852 ENSG00000112290 ENSG00000221823 ENSG00000277586 ENSG00000068976 ENSG00000065518 ENSG00000197971 ENSG00000148798 ENSG00000189043 ENSG00000101438 ENSG00000132164 ENSG00000154654 ENSG00000139190 ENSG00000120251 ENSG00000198910 PMC5406854__F2 Ways of targeting MYC and its transcriptional output using specific signaling pathway, BET bromodomain, and complex inhibitors in MYC-dependent malignancies ENSG00000141867 ENSG00000101751 ENSG00000136997 ENSG00000167074 ENSG00000087586 ENSG00000109670 PMC12250682__F7 Multifaceted antitumour mechanisms of Astragalus polysaccharides (APS) in liver cancer ENSG00000170558 PMC7924210__F2 Simplified mechanism of the classical endocannabinoid ligand signaling pathway ENSG00000275723 ENSG00000117480 PMC6718562__F6 Role of IL-1 cytokine family members in the immunological history of the hepatocarcinoma ENSG00000162711 ENSG00000111537 ENSG00000137033 ENSG00000109321 ENSG00000158825 PMC7814617__F7 Schematic model for the mechanism of action of anemoside B4 in the treatment of colitis ENSG00000163220 ENSG00000136869 PMC8182917__F1 Estrogen/ER in anti-tumor immunity regulation to tumor cell and tumor microenvironment ENSG00000157554 ENSG00000168036 ENSG00000129514 ENSG00000107485 PMC5666320__F6 Model of Rho/F-actin pathway repression by EWS-FLI1 via MRTFB/YAP-1/TEAD transcriptional perturbation ENSG00000186260 ENSG00000122786 ENSG00000140416 PMC5582828__F2 Mechanisms by which fusion genes promote kinase activation and cell survival and opportunities for therapeutic intervention ENSG00000186716 ENSG00000292363 PMC7772217__F3 Role of the inflammasome complex in modulating immune responses in a Toxoplasma gondii infection ENSG00000162711 ENSG00000117228 ENSG00000187796 ENSG00000091592 ENSG00000064012 PMC4503882__F4 Postulated signaling pathway for MMF through binding to HCAR2 ENSG00000105835 ENSG00000125538 ENSG00000110931 ENSG00000096717 PMC11675326__F19 Single-Cell Transcriptome Reveals the Heterogeneity of T Cells in Mice with Systemic Lupus Erythematosus and Neuronal Inflammation ENSG00000142192 ENSG00000167207 ENSG00000156026 ENSG00000168040 PMC11675326__F18 Single-Cell Transcriptome Reveals the Heterogeneity of T Cells in Mice with Systemic Lupus Erythematosus and Neuronal Inflammation ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000169047 ENSG00000104894 PMC5411695__F3 Hedgehog (Hh) signal transduction in the primary cilium ENSG00000143147 ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC11675326__F17 Single-Cell Transcriptome Reveals the Heterogeneity of T Cells in Mice with Systemic Lupus Erythematosus and Neuronal Inflammation ENSG00000087095 ENSG00000170458 ENSG00000179091 ENSG00000102871 ENSG00000130522 ENSG00000172936 ENSG00000175104 ENSG00000127191 ENSG00000081189 ENSG00000132341 ENSG00000026103 PMC3236573__F3 Ovarian cancer ascites-mediated protection from TRAIL-induced apoptosis ENSG00000168040 PMC6212884__F1 Canonical TGFB/SMAD signaling pathway PMC9035937__F4 Advances in the Role of Endothelial Cells in Cerebral Small Vessel Disease ENSG00000112715 ENSG00000162692 PMC11742290__F2 LGR5 in the WNT/Beta-catenin pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000136997 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC11647666__F7 Proteome analysis after Mg treatment for t = 2 days ENSG00000228716 ENSG00000169814 ENSG00000142798 ENSG00000131495 ENSG00000134910 ENSG00000099624 ENSG00000278488 ENSG00000126088 ENSG00000213614 ENSG00000095380 ENSG00000147894 ENSG00000204262 ENSG00000157184 ENSG00000149089 ENSG00000213949 ENSG00000041982 ENSG00000185015 ENSG00000247626 ENSG00000068976 ENSG00000128609 ENSG00000291814 ENSG00000165434 ENSG00000160216 ENSG00000173614 ENSG00000108821 ENSG00000276600 ENSG00000106348 ENSG00000110497 ENSG00000150787 ENSG00000182621 ENSG00000186298 ENSG00000214013 ENSG00000101365 ENSG00000187134 ENSG00000241837 ENSG00000060642 ENSG00000291748 ENSG00000084636 ENSG00000164023 ENSG00000158470 ENSG00000139410 PMC5754510__F1 Important growth factors and cellular signalling pathways involved in tumourigenesis and angiogenesis of NETs ENSG00000149311 ENSG00000180447 ENSG00000002330 ENSG00000169047 ENSG00000168036 ENSG00000250506 ENSG00000123374 ENSG00000105810 ENSG00000128602 PMC3760066__F2 Two TLR signaling pathways ENSG00000183735 ENSG00000170458 ENSG00000172005 ENSG00000172936 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC10452677__F1 Relevance network of genes, transcription factors, small molecules, functional classes, miRNA, and biological processes that are shared between DMD and HMB (based on Pathway Studio Web Mammalian) ENSG00000111046 ENSG00000111537 ENSG00000105329 ENSG00000158022 ENSG00000150907 ENSG00000108342 ENSG00000096717 PMC3393470__F1 Chemical structures of PSI-352938 and its potential metabolites and the proposed metabolic pathway of PSI-352938 activation ENSG00000196839 PMC11675326__F21 Single-Cell Transcriptome Reveals the Heterogeneity of T Cells in Mice with Systemic Lupus Erythematosus and Neuronal Inflammation ENSG00000169291 ENSG00000002330 ENSG00000070831 ENSG00000173156 ENSG00000100744 ENSG00000175104 PMC3587990__F4 Interaction of marine compounds on survival and apoptotic signaling molecules ENSG00000002330 ENSG00000198793 PMC3587990__F3 Pathway of apoptosis ENSG00000002330 ENSG00000171791 PMC3348077__F7 Signaling pathway for the cytoprotective effect of STI571 in TRAIL-treated colon cancer cells ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC3587990__F2 Scheme of survival signaling cascade by receptor tyrosine kinases via PI3K/AKT mediated survival ENSG00000002330 ENSG00000005882 ENSG00000198793 PMC11675326__F20 Single-Cell Transcriptome Reveals the Heterogeneity of T Cells in Mice with Systemic Lupus Erythematosus and Neuronal Inflammation ENSG00000149311 ENSG00000175054 ENSG00000156026 ENSG00000198125 PMC6542064__F7 Temporal dependence of G2/M DNA replication checkpoint mechanism on the G1/S transition mechanism ENSG00000145604 ENSG00000094804 ENSG00000198176 ENSG00000123374 ENSG00000112118 ENSG00000139687 ENSG00000124762 ENSG00000134480 ENSG00000093009 PMC3587990__F1 Scheme of PI3K/AKT mediated antiapoptotic regulations at the mitochondria ENSG00000002330 ENSG00000198793 PMC5384880__F8 Physiological development-functions associated with the dorsal hippocampus and nucleus accumbens of ENT1−/− mice ENSG00000091664 ENSG00000152661 ENSG00000137177 ENSG00000087085 ENSG00000137845 ENSG00000187714 ENSG00000112290 ENSG00000172292 ENSG00000171720 ENSG00000101438 ENSG00000120251 ENSG00000165646 ENSG00000112759 ENSG00000148339 ENSG00000276996 ENSG00000198910 ENSG00000154096 ENSG00000151012 ENSG00000129244 ENSG00000170075 ENSG00000162512 ENSG00000011021 ENSG00000078668 ENSG00000145248 ENSG00000103150 ENSG00000132639 ENSG00000145920 ENSG00000179915 ENSG00000221823 ENSG00000047579 ENSG00000277586 ENSG00000177189 ENSG00000169220 ENSG00000110076 ENSG00000010810 ENSG00000157445 ENSG00000154146 ENSG00000292254 ENSG00000196517 PMC5748601__F1 TLR4 Signaling Pathway Modulators as Potential Therapeutics in Inflammation and Sepsis ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC2861144__F1 Novel targets for the treatment of autosomal dominant polycystic kidney disease ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000136997 ENSG00000001626 PMC2861144__F2 Novel targets for the treatment of autosomal dominant polycystic kidney disease ENSG00000169047 ENSG00000198793 PMC4951239__F2 Functional role of autophagy in gastric cancer ENSG00000198793 ENSG00000096717 PMC266780__F7 Scheme to illustrate the separate functions and regulation of conventional nonsarcomeric myosin IIA and myosin IIB ENSG00000163914 ENSG00000198670 PMC9179868__F1 Crosstalk of Epigenetic and Metabolic Signaling Underpinning Glioblastoma Pathogenesis ENSG00000160883 ENSG00000274437 ENSG00000146648 ENSG00000159399 ENSG00000145088 ENSG00000079999 PMC4429169__F1 Network uncovered using IPA ENSG00000168209 ENSG00000111729 ENSG00000163558 ENSG00000189001 ENSG00000174607 PMC4038542__F1 Complement activation and effector functions ENSG00000039537 ENSG00000113600 ENSG00000236625 PMC7423983__F3 Function of SIK1 in tumorigenesis ENSG00000169554 ENSG00000138795 ENSG00000171720 ENSG00000142178 ENSG00000122691 ENSG00000168036 ENSG00000196628 ENSG00000125968 PMC7423983__F2 Roles of SIKs in the regulation of glucose, lipid metabolism and inflammation are illustrated ENSG00000169047 ENSG00000136869 ENSG00000175104 ENSG00000124253 ENSG00000026103 PMC7097452__F2 Prognostic and predictive enrichment in sepsis ENSG00000123975 ENSG00000168329 ENSG00000168209 ENSG00000185022 ENSG00000090104 ENSG00000105329 ENSG00000291920 ENSG00000164935 ENSG00000198056 ENSG00000136695 ENSG00000131669 ENSG00000113905 ENSG00000272398 ENSG00000169429 ENSG00000123689 ENSG00000086730 ENSG00000127074 PMC5453186__F3 Clostridium difficile infection ENSG00000162711 ENSG00000187554 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000106100 ENSG00000115594 PMC6537480__F2 Signaling pathway mediating cardiovascular protection of OT ENSG00000172680 ENSG00000116688 ENSG00000084774 PMC10939994__F2 Correlation of HDAC7 and three signaling pathways ENSG00000002330 ENSG00000134982 ENSG00000061273 ENSG00000168610 PMC7179196__F1 PPARA and PPARG signal cascade following their activation by endogenous or synthetic ligands PMC11886387__F3 McCullough protocol: Base spike detoxification ENSG00000130234 ENSG00000136869 ENSG00000122194 PMC8908152__F6 Expression profiles of tRNA-derived fragments and their potential roles in lung adenocarcinoma ENSG00000179091 ENSG00000102871 ENSG00000026103 PMC6103720__F4 Autophagy contributes to integrin recycling and degradation ENSG00000177169 ENSG00000291971 ENSG00000132405 ENSG00000132698 PMC8892718__F3 Proton Pump Inhibitor Therapy for Eosinophilic Esophagitis: History, Mechanisms, Efficacy, and Future Directions ENSG00000137033 ENSG00000145777 ENSG00000006606 ENSG00000106546 PMC3154366__F4 c-Myc regulates the rate limiting steps at the entry into glycolysis ENSG00000130957 ENSG00000160883 ENSG00000067057 ENSG00000136872 ENSG00000159399 ENSG00000013375 ENSG00000152556 PMC9028333__F1 Cannabis Biomolecule Effects on Cancer Cells and Cancer Stem Cells: Cytotoxic, Anti-Proliferative, and Anti-Migratory Activities ENSG00000128272 ENSG00000002330 ENSG00000101255 ENSG00000198793 ENSG00000125968 PMC7791970__F7 Schema of the signaling pathway involved in HSP60-mediated NLRP3 inflammasome activation and subsequent IL-1B production ENSG00000162711 ENSG00000172936 ENSG00000136869 PMC12048151__F1 How two mutations associated with developmental defects impact BMP4 secretion ENSG00000288499 PMC6757435__F9 Signaling pathway proposed in this study ENSG00000156299 PMC8038777__F2 Granulocytes role in CRC ENSG00000111537 ENSG00000275718 ENSG00000163220 ENSG00000163739 ENSG00000125538 ENSG00000118520 ENSG00000166090 ENSG00000277943 ENSG00000106178 PMC9669439__F2 Orchestration of mesenchymal plasticity and immune evasiveness via rewiring of the metabolic program in pancreatic ductal adenocarcinoma ENSG00000185236 ENSG00000131473 ENSG00000060982 ENSG00000169710 ENSG00000165527 ENSG00000105552 ENSG00000115419 ENSG00000159399 PMC4980741__F2 Signaling pathways regulated by SHP-2 in the gastrointestinal tract ENSG00000019991 ENSG00000138798 ENSG00000169047 ENSG00000168036 ENSG00000168610 PMC8744322__F7 Modification of mesenchymal stem cells by HMGB1 promotes the activity of Cav3.2 T-type calcium channel via PKA/Beta-catenin/Gamma-cystathionase pathway ENSG00000168036 ENSG00000189403 ENSG00000116761 PMC6580874__F3 Simplified schematic of the PI3K pathway, which highlights the common targets for small molecule inhibitors ENSG00000169047 ENSG00000198793 ENSG00000164327 ENSG00000139618 PMC7507442__F1 DNA damage and the programmed cell death pathway (apoptosis) induced by radiotherapy ENSG00000149311 ENSG00000175054 ENSG00000113456 ENSG00000171791 ENSG00000168040 ENSG00000138385 PMC3215281__F7 Hijacking of the mismatch repair system to cause CAG expansion and cell death in neurodegenerative disease ENSG00000012061 ENSG00000132646 ENSG00000136936 PMC9371512__F6 The Bushen Huoxue formula in the treatment of osteoarthritis based on network pharmacology-molecular targets ENSG00000262406 ENSG00000087245 ENSG00000157764 ENSG00000291971 ENSG00000173039 ENSG00000173083 ENSG00000007908 ENSG00000213341 ENSG00000171791 ENSG00000073756 ENSG00000178726 ENSG00000164305 ENSG00000132170 ENSG00000169245 ENSG00000108691 ENSG00000149968 ENSG00000128052 ENSG00000177606 ENSG00000136997 ENSG00000026508 ENSG00000169429 ENSG00000100985 ENSG00000005381 PMC2195911__F10 A molecular mechanism whereby cAMP inhibits T cell function PMC3485057__F4 Increased Biomass Yield of Lactococcus lactis by Reduced Overconsumption of Amino Acids and Increased Catalytic Activities of Enzymes ENSG00000110711 PMC3765067__F2 Map of molecular interactions involving GADD45 proteins and cell signaling pathways generated using Ingenuity Pathway Analysis software (IPA) ENSG00000012048 ENSG00000132646 ENSG00000136997 ENSG00000051180 PMC4036354__F1 Cross-talk between Two Signaling Pathways Drives Aggressive Late-stage Breast Cancer♦ ENSG00000172260 PMC11575037__F16 Selected subnetwork of the differential network for Artery Tibial tissue in Atherosclerosis ENSG00000019991 ENSG00000164761 ENSG00000080823 PMC11575037__F14 Figure shows selected subnetwork of the differential network for Artery Coronary tissue in Atherosclerosis ENSG00000197635 ENSG00000080823 ENSG00000005381 ENSG00000132170 PMC8600921__F1 Cytokine release syndrome and neurotoxicity of CAR T-cell therapy and associated prevention and management strategies ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000145649 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000073605 PMC6204373__F2 TRAFs in canonical and non-canonical NFKB signaling pathways ENSG00000104856 ENSG00000082512 ENSG00000056558 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC9357337__F4 ELIMINATOR: essentiality analysis using multisystem networks and integer programming ENSG00000154342 ENSG00000155760 ENSG00000157240 PMC6204373__F1 Role of TRAFs in TCR-, costimulatory receptor-, and cytokine receptor-associated signaling pathways controlling TFH differentiation ENSG00000183735 ENSG00000115415 ENSG00000082512 ENSG00000056558 ENSG00000103522 ENSG00000131323 ENSG00000175104 ENSG00000127191 ENSG00000168610 ENSG00000168685 PMC9357337__F3 ELIMINATOR: essentiality analysis using multisystem networks and integer programming ENSG00000154342 ENSG00000155760 ENSG00000157240 PMC4539521__F6 Changes in gene expression and MAPK signaling pathways in Cgasg1Δ and Cghal9Δ strains ENSG00000070831 PMC9514850__F9 Differential metabolic pathway and reaction analysis ENSG00000234068 ENSG00000197386 PMC8702253__F8 Exploring potential mechanisms of Suhexiang Pill against COVID-19 based on network pharmacology and molecular docking ENSG00000138798 ENSG00000169047 ENSG00000115904 ENSG00000110324 ENSG00000112715 ENSG00000168610 ENSG00000179295 ENSG00000163235 ENSG00000124882 ENSG00000167941 ENSG00000128052 ENSG00000113520 ENSG00000146648 ENSG00000150630 PMC5654621__F1 Endosomal traffic jams represent a pathogenic hub and therapeutic target in Alzheimer’s disease ENSG00000142192 ENSG00000073921 ENSG00000137642 PMC6173469__F1 Genomic mechanisms of immune evasion in colorectal cancer: from discovery to clinical practice ENSG00000134982 ENSG00000168036 ENSG00000273686 PMC6030495__F6 EGFRvIII-Stat5 Signaling Enhances Glioblastoma Cell Migration and Survival ENSG00000291971 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC7985675__F2 Retortamonads from vertebrate hosts share features of anaerobic metabolism and pre-adaptations to parasitism with diplomonads ENSG00000110711 ENSG00000182511 ENSG00000134042 PMC3346698__F8 One of the KEGG prostate cancer pathways (b) the paths detected by our method ENSG00000105401 ENSG00000168310 ENSG00000171791 ENSG00000146648 ENSG00000089159 PMC4958958__F1 PACSIN2 polymorphism is associated with thiopurine-induced hematological toxicity in children with acute lymphoblastic leukaemia undergoing maintenance therapy ENSG00000228716 ENSG00000100714 ENSG00000137364 ENSG00000124275 ENSG00000116984 PMC3346698__F5 The main chain path of pheromone response pathway (b) the assembly paths detected by Scott et al ENSG00000070831 ENSG00000197601 PMC4944657__F6 Antagonizing integrin beta3 increases immune suppression in cancer ENSG00000115415 ENSG00000136869 PMC3318612__F8 Summary model of rAdV-sensing cascades in RAW 264.7 cell line ENSG00000101751 ENSG00000239732 ENSG00000163568 ENSG00000172936 ENSG00000276561 PMC3292304__F4 Gene functional association networks for selected pathways in p53 dataset ENSG00000132906 ENSG00000162889 ENSG00000002330 ENSG00000175793 ENSG00000197471 ENSG00000159388 ENSG00000124383 ENSG00000134308 ENSG00000254445 ENSG00000164399 ENSG00000171791 ENSG00000135698 ENSG00000164305 ENSG00000096063 ENSG00000100290 ENSG00000114503 ENSG00000051825 ENSG00000120868 ENSG00000026103 PMC5187845__F2 Acceleration of osteoblast differentiation through the p53–Akt–FoxO pathway ENSG00000116717 PMC4432802__F1 Schematic representation of the principal pathways involved in glucose catabolism summarizing recent findings discussed in the Mini Review (red boxes) ENSG00000111537 PMC5685326__F1 PD-1 in T-cell activation, exhaustion, and effector function ENSG00000134982 PMC5892988__F1 BMP receptor signaling pathway ENSG00000170365 ENSG00000137834 PMC3606422__F1 Methotrexate mode of action ENSG00000228716 ENSG00000136877 ENSG00000196839 ENSG00000103222 ENSG00000035928 ENSG00000137563 ENSG00000118777 ENSG00000023839 PMC6953796__F4 Targeted transcriptomic study of the implication of central metabolic pathways in mannosylerythritol lipids biosynthesis in Pseudozyma antarctica T-34 ENSG00000122966 ENSG00000173599 PMC5892988__F3 Roles of the BMP system in steroidogenesis and mitogenesis in growing follicles ENSG00000130385 PMC6087588__F2 Proposed signaling mechanisms of adiponectin in prevention of ischemic stroke ENSG00000159346 ENSG00000285070 ENSG00000162692 PMC5971020__F1 RIG-I-like receptor signaling pathway ENSG00000152684 ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000023697 PMC4939324__F3 Anti-inflammatory mechanisms of MFG-E8 in a LPS-TLR4 signaling pathway ENSG00000170458 ENSG00000136869 ENSG00000168610 PMC8286283__F3 Cellular roles of ER-phagy and the contributions of metazoan ER-phagy receptors ENSG00000008952 ENSG00000164081 ENSG00000184743 ENSG00000260916 PMC8249453__F4 Machine learning compensates fold-change method and highlights oxidative phosphorylation in the brain transcriptome of Alzheimer’s disease ENSG00000178127 ENSG00000132906 ENSG00000183648 ENSG00000169021 ENSG00000002330 ENSG00000147684 ENSG00000184983 ENSG00000184752 ENSG00000156026 ENSG00000189043 ENSG00000129007 PMC4905711__F1 Role of Nrf2 and Autophagy in Acute Lung Injury ENSG00000178573 ENSG00000100387 ENSG00000023909 ENSG00000079999 PMC8536203__F10 Proteomic Landscape of Extracellular Vesicles for Diffuse Large B-Cell Lymphoma Subtyping ENSG00000070190 ENSG00000104365 ENSG00000105369 ENSG00000282905 ENSG00000269335 ENSG00000110651 ENSG00000213341 ENSG00000169032 ENSG00000274513 ENSG00000010671 ENSG00000177455 ENSG00000095585 ENSG00000072694 ENSG00000166501 ENSG00000145321 ENSG00000197943 ENSG00000160293 ENSG00000155629 ENSG00000131196 ENSG00000198286 PMC3886588__F1 Targeting the Th17 pathway ENSG00000162594 ENSG00000125538 ENSG00000103522 ENSG00000163702 PMC5811630__F7 Iron starvation responses ENSG00000161634 ENSG00000128951 ENSG00000291814 ENSG00000198670 PMC3921548__F1 Overview of arachidonic acid metabolism ENSG00000226275 PMC2713571__F1 Proposed cuticle pigmentation and sclerotization metabolic pathway in T PMC4682646__F1 Complement activation, regulation, and molecular basis for complement‐related diseases ENSG00000226275 ENSG00000088888 ENSG00000196352 ENSG00000117335 ENSG00000244731 ENSG00000166278 ENSG00000132693 ENSG00000236625 PMC8511314__F9 Lysophosphatidic Acid–Induced EGFR Transactivation Promotes Gastric Cancer Cell DNA Replication by Stabilizing Geminin in the S Phase ENSG00000198793 ENSG00000198670 ENSG00000171517 ENSG00000146648 PMC7410257__F7 Kinase inhibitor screen identifies signaling pathways regulating mucosal growth during otitis media ENSG00000198793 ENSG00000177606 ENSG00000105639 ENSG00000146648 ENSG00000086730 PMC7322393__F1 Zoledronic acid (ZA) acts as immunostimulant and endosomal disruptor of dendritic cell in SARS-CoV-2 infection ENSG00000158477 ENSG00000197429 ENSG00000112149 PMC9317349__F1 Present Status, Challenges, and Prospects of Dihydromyricetin in the Battle against Cancer ENSG00000198793 ENSG00000086991 ENSG00000185591 ENSG00000168610 PMC4155175__F3 mGluR1-TRPC3 signaling at parallel fiber-Purkinje cell synapses ENSG00000163914 ENSG00000138741 PMC8861314__F6 Asiatic Acid Attenuates Osteoporotic Bone Loss in Ovariectomized Mice Through Inhibiting NF-kappaB/MAPK/ Protein Kinase B Signaling Pathway ENSG00000164935 ENSG00000102575 ENSG00000131196 ENSG00000143387 PMC5880173__F1 Bone morphogenetic protein (BMP) pathway and potential strategies for therapeutic modulation ENSG00000170365 PMC3825489__F3 Cross talk between the coagulation and complement system ENSG00000009724 ENSG00000166278 ENSG00000122194 PMC5622528__F9 Hexokinases link DJ-1 to the PINK1/parkin pathway ENSG00000169047 ENSG00000159399 ENSG00000140443 PMC5038858__F3 The Notch pathway in ovarian (A) clear cell carcinoma ES2 and (B) serous carcinoma OVCAR3 cells following exposure to vorinostat ENSG00000135547 ENSG00000148400 ENSG00000062485 PMC10528301__F3 An Overview of CD133 as a Functional Unit of Prognosis and Treatment Resistance in Glioblastoma ENSG00000175793 ENSG00000105401 ENSG00000171791 ENSG00000073756 ENSG00000187840 PMC9105159__F1 Wnt/Beta-catenin pathway modulation via DKK1 inhibition ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5744151__F2 Restriction factors block multiple stages in the influenza virus life cycle ENSG00000112576 ENSG00000187608 ENSG00000119401 ENSG00000057294 ENSG00000169871 ENSG00000172183 ENSG00000167080 ENSG00000185201 ENSG00000142089 ENSG00000084073 ENSG00000111331 ENSG00000135828 ENSG00000155363 PMC11596795__F5 Metabolic pathway and relative abundance of key genes of DAMO bacteria (a–c) and DAMO archaea (d–f), with predicted metabolic function as recorded in KEGG ENSG00000116984 PMC5733031__F1 Role of SOCS proteins in the regulation of the signaling pathways induced by recognition of gram-negative bacteria ENSG00000172005 ENSG00000172936 ENSG00000136869 PMC10807637__F6 HDAC inhibitors target IRS4 to enhance anti-AR therapy in AR-positive triple-negative breast cancer ENSG00000198793 ENSG00000133124 PMC5733031__F2 Role of SOCS proteins in the regulation of the signaling pathways induced by recognition of gram positive bacteria ENSG00000174125 ENSG00000226275 ENSG00000172005 ENSG00000172936 PMC8019794__F3 Macroautophagy pathway and signaling ENSG00000177169 ENSG00000152348 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC6093783__F31 The biosynthetic pathway of polyoxin 292 ENSG00000101751 ENSG00000177084 ENSG00000166169 ENSG00000122008 ENSG00000122678 PMC4339403__F3 Unfolded Protein Response in Retinal Vascular Diseases: Implications and Therapeutic Potential Beyond Protein Folding ENSG00000100219 PMC4132813__F8 Model depicting the role of the PP1A signaling pathway in coordinating the activation of BRD4 and P-TEFb for inducible gene expression ENSG00000136807 ENSG00000141867 ENSG00000186834 PMC9319031__F2 Comprehensive Review on the Benefits and Problems of Curcumin with Respect to Human Health ENSG00000189060 ENSG00000135446 ENSG00000132646 ENSG00000198793 ENSG00000170430 ENSG00000110693 PMC5340233__F4 SIN3A and SIN3B differentially regulate breast cancer metastasis ENSG00000125285 ENSG00000102871 ENSG00000118971 PMC8124706__F1 Targeting BRAF and RAS in Colorectal Cancer ENSG00000177606 ENSG00000136997 ENSG00000115904 ENSG00000146648 PMC5889941__F1 Alterations in glucose and glutamine metabolism contribute to tumor growth and proliferation ENSG00000092621 ENSG00000115419 PMC6247426__F1 Metabolic reprogramming in HCC ENSG00000131473 ENSG00000135218 ENSG00000122966 ENSG00000172005 ENSG00000169710 ENSG00000159399 PMC3964053__F4 BMP signaling in germ cells across the Metazoa ENSG00000170365 ENSG00000147596 ENSG00000133937 ENSG00000096088 ENSG00000204217 PMC4881575__F1 miRNA network regulating cancer metabolism ENSG00000198793 ENSG00000136997 ENSG00000026103 PMC3506510__F2 Signaling pathways impinging on autophagy ENSG00000198793 ENSG00000164327 PMC6400995__F1 Kynurenine pathway with a focus on KYNA synthesis ENSG00000162882 ENSG00000106546 PMC3739348__F6 Expression of some genes related to the cell cycle and apoptosis were significantly changed after LM23 knockdown, as shown by microarray analysis ENSG00000134982 ENSG00000138794 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000026103 PMC5549304__F6 H3K79 methylation pathway and potential therapeutic targets ENSG00000141867 ENSG00000155827 ENSG00000095787 PMC2694487__F5 Human presenilin 1 and 2 (PSEN1 and PSEN2) subnetworks ENSG00000143801 ENSG00000170775 ENSG00000205155 ENSG00000106003 PMC5103945__F1 STRING analysis of metabolic and PI3K-Akt signalling pathways ENSG00000151726 ENSG00000165119 ENSG00000134308 ENSG00000197746 ENSG00000178209 ENSG00000169710 ENSG00000143933 ENSG00000292029 ENSG00000092820 ENSG00000163815 ENSG00000106927 ENSG00000224320 ENSG00000130402 ENSG00000127824 ENSG00000112306 ENSG00000146701 PMC4216117__F2 MicroRNA Network Dysregulated in Asthma Controls IL-6 Production in Bronchial Epithelial Cells ENSG00000104365 ENSG00000166130 ENSG00000172216 ENSG00000198793 ENSG00000167604 ENSG00000168310 PMC4307283__F4 Lipids regulate apoptotic signaling in the cells ENSG00000132906 ENSG00000138794 ENSG00000137757 ENSG00000196954 ENSG00000064012 ENSG00000164305 PMC4519426__F5 Genome-wide mapping of DNA hydroxymethylation in osteoarthritic chondrocytes ENSG00000140564 ENSG00000167720 ENSG00000113070 ENSG00000095015 ENSG00000196591 ENSG00000168036 ENSG00000164327 ENSG00000112715 ENSG00000090932 ENSG00000157240 ENSG00000145604 ENSG00000197530 ENSG00000107186 ENSG00000100387 ENSG00000163235 ENSG00000132646 ENSG00000139517 ENSG00000026508 ENSG00000179111 ENSG00000133961 ENSG00000124795 ENSG00000177283 PMC5374431__F1A Protein Kinase CK2: Intricate Relationships within Regulatory Cellular Networks ENSG00000004975 ENSG00000092201 ENSG00000196591 ENSG00000168036 ENSG00000101266 ENSG00000196396 ENSG00000171720 ENSG00000150991 ENSG00000006712 ENSG00000175115 ENSG00000136997 ENSG00000269404 ENSG00000140464 ENSG00000169375 ENSG00000111707 ENSG00000114125 ENSG00000107404 ENSG00000100906 ENSG00000131747 ENSG00000173039 ENSG00000100083 ENSG00000143933 ENSG00000150459 ENSG00000007168 ENSG00000149136 ENSG00000177606 ENSG00000161202 ENSG00000175390 ENSG00000096717 ENSG00000108312 PMC5779957__F8 The top one Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of miR-146a-5p, hsa05200: Pathways in cancer ENSG00000198670 PMC6691931__F3 CD40 signalling pathway ENSG00000162889 ENSG00000226275 ENSG00000082512 ENSG00000056558 ENSG00000131323 ENSG00000104921 ENSG00000105639 ENSG00000175104 ENSG00000127191 ENSG00000168610 ENSG00000123268 PMC7277573__F3 “Clathrin-coated vesicle cycle” pathway was enriched in both sexes ENSG00000130340 ENSG00000102189 ENSG00000143761 ENSG00000220205 ENSG00000073921 ENSG00000274145 ENSG00000118640 ENSG00000292366 PMC5910217__F2 Interferon system ENSG00000213928 ENSG00000164430 ENSG00000088888 ENSG00000105397 ENSG00000276561 ENSG00000142166 PMC8424549__F4 Regulation and metabolic functions of mTORC1 and mTORC2 ENSG00000178035 ENSG00000065911 ENSG00000136997 ENSG00000153574 ENSG00000084774 ENSG00000254550 PMC8424549__F7 Regulation and metabolic functions of mTORC1 and mTORC2 ENSG00000198793 ENSG00000112561 ENSG00000197386 PMC3948775__F2 Pathway Based Analysis of Genes and Interactions Influencing Porcine Testis Samples from Boars with Divergent Androstenone Content in Back Fat ENSG00000149084 ENSG00000132196 ENSG00000108786 ENSG00000088002 ENSG00000203857 ENSG00000176387 PMC7092451__F6 KEGG pathway analysis of targeted genes involved into proteoglycans in cancer pathway ENSG00000180353 ENSG00000108654 ENSG00000100485 ENSG00000092820 ENSG00000291420 PMC3948775__F9 Pathway Based Analysis of Genes and Interactions Influencing Porcine Testis Samples from Boars with Divergent Androstenone Content in Back Fat ENSG00000038002 PMC8230743__F13 Gene Expression Profile and Co-Expression Network of Pearl Gentian Grouper under Cold Stress by Integrating Illumina and PacBio Sequences ENSG00000180210 ENSG00000159224 ENSG00000171105 ENSG00000002330 ENSG00000122966 ENSG00000198793 ENSG00000096088 ENSG00000100504 ENSG00000096717 ENSG00000160741 ENSG00000026103 PMC6359475__F1 Extrinsic and intrinsic pathways of apoptosis ENSG00000168040 PMC8230743__F12 Gene Expression Profile and Co-Expression Network of Pearl Gentian Grouper under Cold Stress by Integrating Illumina and PacBio Sequences ENSG00000145604 ENSG00000180210 ENSG00000149311 ENSG00000087095 ENSG00000171105 ENSG00000135218 ENSG00000123374 ENSG00000001626 ENSG00000145782 ENSG00000164087 ENSG00000026103 PMC7522985__F1 Biosynthesis and Metabolism of n-6 PUFAs and LC-PUFAs ENSG00000151726 ENSG00000283887 ENSG00000161905 ENSG00000134824 ENSG00000196839 ENSG00000149485 ENSG00000111684 ENSG00000197142 ENSG00000166278 ENSG00000148344 ENSG00000124212 ENSG00000273592 PMC8102494__F1 Conserved apoptotic pathways ENSG00000168040 ENSG00000026103 PMC9612159__F2 Nano-Based Drug Delivery Systems for Periodontal Tissue Regeneration ENSG00000148908 ENSG00000170909 ENSG00000101307 ENSG00000131196 ENSG00000159788 PMC8869658__F1 Research Progress on Cordycepin Synthesis and Methods for Enhancement of Cordycepin Production in Cordyceps militaris ENSG00000156110 ENSG00000196839 ENSG00000198931 PMC7956574__F3 Wnt/Beta-catenin signaling pathway in osteogenesis ENSG00000134982 ENSG00000168036 ENSG00000104332 PMC7956574__F2 BMPs and TGFB signaling pathways in osteogenesis ENSG00000198742 PMC5555817__F2 Association analysis between chemical activity in the p53RE assay and chemical-induced increased expression of downstream genes in the p53 signaling pathway ENSG00000149311 ENSG00000175054 ENSG00000136997 PMC4034436__F1 Effects of the HIF pathway on mesenchymal stem cells (MSCs) ENSG00000178860 ENSG00000121966 PMC3627370__F1 NAMPT in mammalian NAD metabolism ENSG00000105835 ENSG00000123572 PMC12175451__F1 Circadian clock entrainment pathways ENSG00000132326 ENSG00000069667 PMC8720586__F3 Target Deconvolution of Fenofibrate in Nonalcoholic Fatty Liver Disease Using Bioinformatics Analysis ENSG00000245848 ENSG00000171105 ENSG00000128272 ENSG00000173039 PMC12175451__F2 Related signaling pathway ENSG00000136869 ENSG00000116717 ENSG00000179094 ENSG00000168610 PMC9005294__F3 Involvement of WDHD1 in the Occurrence of Esophageal Cancer as a Downstream Target of PI3K/AKT Pathway ENSG00000124102 ENSG00000087245 ENSG00000002330 ENSG00000005882 ENSG00000100985 PMC12232070__F12 Mechanism of RME inhibiting the secretion of inflammatory factors by regulating the Dvl1/Wnt1/Beta-catenin/GSK-3B signaling pathway in the treatment of RA ENSG00000107404 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000125084 PMC2597184__F2 Nuclear Factor-kappa B Signaling in Skeletal Muscle Atrophy ENSG00000104856 ENSG00000173039 ENSG00000111321 PMC5181590__F3 Specific intracellular signalling pathways are predicted to be abnormally activated in resting HD monocytes ENSG00000170458 ENSG00000136997 ENSG00000136869 ENSG00000168610 PMC3491070__F3A Cancer Cell Metabolism: One Hallmark, Many Faces ENSG00000134086 ENSG00000136997 PMC1951379__F6 IFN signaling during the clinical evolution of SARS ENSG00000105397 ENSG00000115415 ENSG00000185885 PMC5376075__F3 TRL2 pathway is activated by Tollip and results in IRAK suppression ENSG00000173039 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000184216 PMC8232321__F2 BMP Pathway in Blood Vessel and Lymphatic Vessel Biology ENSG00000125266 ENSG00000166292 ENSG00000112715 ENSG00000164619 PMC8232321__F1 BMP Pathway in Blood Vessel and Lymphatic Vessel Biology ENSG00000170365 ENSG00000137834 PMC10531420__F6 Seasonal Developing Xylem Transcriptome Analysis of Pinus densiflora Unveils Novel Insights for Compression Wood Formation ENSG00000105227 ENSG00000084774 PMC4554190__F3 Illustration of data-enhanced Bayesian network inference ENSG00000115904 ENSG00000169032 PMC4495315__F1 Signaling via the IGF-1R begins with binding of its ligands, IGF-1, IGF-2, or insulin, to the extracellular Alpha-subunit, and this in turn leads to phosphorylation of the intracellular Beta-subunits ENSG00000002330 ENSG00000115457 ENSG00000167779 ENSG00000169047 ENSG00000177606 ENSG00000141753 ENSG00000146678 ENSG00000115461 ENSG00000140443 PMC3405133__F3 Identification of Pathway Deregulation – Gene Expression Based Analysis of Consistent Signal Transduction ENSG00000138795 ENSG00000292149 ENSG00000177606 ENSG00000136997 PMC8630469__F1 Wnt/Beta-Catenin Signaling as a Driver of Hepatocellular Carcinoma Progression: An Emphasis on Molecular Pathways ENSG00000134982 ENSG00000168036 PMC3646329__F2 HIF, hypoxia and the role of angiogenesis in non-small cell lung cancer ENSG00000157764 ENSG00000146648 PMC7892973__F2 Role of irisin-involved integrin signaling cascade in modulating tumor microenvironment remodeling ENSG00000160097 ENSG00000198793 ENSG00000110651 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000168610 PMC8283807__F10 MitoROS-PKCG-mediated endoplasmic reticulum stress (ERS)-dependent induction of the TXNIP/NLRP3 signaling axis ENSG00000162711 ENSG00000128272 ENSG00000265972 PMC7241820__F8 Long noncoding RNA PAHAL modulates locust behavioural plasticity through the feedback regulation of dopamine biosynthesis ENSG00000171759 ENSG00000084110 PMC7373860__F5 Frequently altered cancer pathways for TP53 using gene set enrichment analysis pathway enrichment in hepatocellular carcinoma ENSG00000175054 ENSG00000103479 ENSG00000002330 ENSG00000281449 ENSG00000135446 ENSG00000123374 ENSG00000205250 ENSG00000105810 ENSG00000139687 ENSG00000282899 ENSG00000026103 PMC11806886__F5 Combination strategy to suppress tumor cell proliferation in anti-HER2 resistant PTEN-deficient breast cancer cells ENSG00000135218 ENSG00000198793 ENSG00000169710 PMC7840025__F1 Association of a novel endometrial cancer biomarker panel with prognostic risk, platinum insensitivity, and targetable therapeutic options ENSG00000136492 ENSG00000087586 ENSG00000135476 ENSG00000145386 ENSG00000166851 ENSG00000121879 ENSG00000120539 ENSG00000100100 ENSG00000139618 ENSG00000145604 ENSG00000012048 ENSG00000051180 ENSG00000163507 PMC2794539__F5 Gene Expression Signature of Invasive Potential in Metastatic Melanoma Cells ENSG00000197915 ENSG00000214078 ENSG00000132478 ENSG00000141524 ENSG00000064300 ENSG00000196628 ENSG00000103811 ENSG00000011422 ENSG00000038427 ENSG00000177606 ENSG00000080166 ENSG00000134243 ENSG00000118257 PMC5138060__F1 TNF axis in cancer progression and metastasis ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC6863034__F4 (A–C) The most significance predictive genes for renal ischemia-reperfusion injury (IRI) in the rat model ENSG00000166527 ENSG00000108691 ENSG00000169896 ENSG00000170458 ENSG00000149968 ENSG00000163739 ENSG00000136997 ENSG00000091409 ENSG00000026508 ENSG00000181467 ENSG00000168610 ENSG00000137801 PMC10297376__F2 PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds ENSG00000177169 ENSG00000149212 ENSG00000002330 ENSG00000198793 ENSG00000163914 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC6927050__F8 Schematic diagram of hypoxia-induced pyroptosis in myoblasts ENSG00000009709 ENSG00000278718 ENSG00000162711 PMC1832150__F1 CoQ10biosynthetic pathway with eight known biosynthetic enzymes denoted as COQ1-8 ENSG00000132423 ENSG00000119723 ENSG00000110871 ENSG00000173085 ENSG00000167186 PMC8589438__F1 Anti-cancer drugs often work by the induction of apoptosis ENSG00000002330 ENSG00000104081 PMC3237753__F7 GAq - Ca2+ signaling pathway promotes actin-mediated epidermal wound closure ENSG00000070831 ENSG00000163914 PMC11984396__F3 Diagram of cellular immunity mediated by splenic immunocytes ENSG00000134982 PMC5891205__F9 Radioresistance is associated with G2/M arrest and repression of apoptosis pathway by upregulation of Bcl‐XL, Bcl‐2 and CyclinB1/CDK1 and downregulation of p53, p21, Bax, Caspase‐3 and cleaved PARP in colorectal cancer (CRC) ENSG00000122257 ENSG00000134057 PMC4451058__F2 Prostaglandin pathways in duodenal chemosensing ENSG00000167207 ENSG00000140279 ENSG00000001626 ENSG00000184207 PMC8688651__F1 Network map of apelin-mediated signaling ENSG00000111837 ENSG00000172005 ENSG00000173039 ENSG00000121067 ENSG00000127948 PMC5656035__F3 Proximal components of the TNF signaling pathway ENSG00000102871 ENSG00000056558 ENSG00000168040 ENSG00000127191 PMC7434656__F2 Interactions of TGFB and RAAS signaling PMC4448615__F1 Plant and yeast cell walls (CWs) PMC8628488__F2 Chemical Structure, Hypoglycemic Activity, and Mechanism of Action of Selenium Polysaccharides ENSG00000171105 ENSG00000005882 PMC5966782__F1 Glucose catabolism ENSG00000092621 ENSG00000146733 PMC5536941__F3 APC-dependent role of CtBP in the Wnt/ Beta-catenin pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC11984396__F8 Activation of CAP by electrical cervical nerve stimulation and splenic ultrasound stimulation to combat inflammation PMC6592229__F2 Inhibition of DNA end resection promotes cNHEJ.DYNLL1, shieldin and UBQLN4 inhibit DNA end resection thereby promoting DSB repair by cNHEJ ENSG00000012048 ENSG00000080345 ENSG00000051180 ENSG00000139618 PMC11984396__F6 Molecular mechanisms underlying neuro-immune interactions ENSG00000104321 ENSG00000146469 ENSG00000168610 ENSG00000196689 ENSG00000171051 PMC6592229__F1 Balancing DNA double-strand break (DSB) repair.Homologous recombination repair (HR) and classical non-homologous end joining (cNHEJ) are orchestrated in a balanced DSB repair response ENSG00000012048 ENSG00000051180 ENSG00000139618 PMC4764462__F2 Transcriptional control of cardiac fibroblast plasticity ENSG00000144935 ENSG00000168036 ENSG00000137672 ENSG00000138741 ENSG00000163884 PMC3484588__F4 Cellular affects of TNFA.Tumour Necrosis Factor alpha (TNFA) is produced by macrophages, lymphocytes, fibroblasts and keratinocyte ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC11670415__F1 Necroptosis activation in AD ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC3482685__F2 Regulatory function of TIR8/SIGIRR in signaling ENSG00000239732 ENSG00000187554 ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000185187 ENSG00000164342 PMC9237949__F7 Modularisation of published and novel models toward a complex KIR2DL4 pathway in pbNK cell PMC12027629__F1 Keratinocyte-derived EVs modulate immune cells and promote inflammation in psoriasis ENSG00000111537 ENSG00000163739 ENSG00000163734 ENSG00000169429 ENSG00000124875 PMC6895929__F2 Molecular networks enriched by miRNAs differentially expressed in H1299/mutant p53R273H cells ENSG00000106123 ENSG00000095739 ENSG00000038427 ENSG00000164109 ENSG00000115268 ENSG00000134575 ENSG00000111371 ENSG00000182759 ENSG00000104447 ENSG00000164654 ENSG00000109586 PMC9237949__F1 Modularisation of published and novel models toward a complex KIR2DL4 pathway in pbNK cell ENSG00000276051 PMC4976833__F1 Cell density regulates cancer metastasis via the Hippo pathway ENSG00000126016 ENSG00000150457 ENSG00000291442 PMC5095034__F7 Soluble factors from stellate cells induce pancreatic cancer cell proliferation via Nrf2-activated metabolic reprogramming and ROS detoxification ENSG00000168610 ENSG00000121966 PMC11560455__F1 Ferroptosis signaling pathway ENSG00000138449 ENSG00000167468 ENSG00000072274 ENSG00000111684 ENSG00000102967 ENSG00000115107 PMC8913698__F8 Co-functioning of 2AP precursor amino acids enhances 2-acetyl-1-pyrroline under salt stress in aromatic rice (Oryza sativa L.) cultivars PMC7403513__F11 The impact of CFTR dysfunction in HLMVEC on oxidative stress, inflammation and angiogenesis ENSG00000001626 ENSG00000146648 PMC8991687__F1 Targeting Chemokine Receptor CCR1 as a Potential Therapeutic Approach for Multiple Myeloma PMC9285118__F1 Gasdermins: New Therapeutic Targets in Host Defense, Inflammatory Diseases, and Cancer ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC5567913__F9 Graphical summary of the results ENSG00000136535 ENSG00000086991 PMC9285118__F2 Gasdermins: New Therapeutic Targets in Host Defense, Inflammatory Diseases, and Cancer ENSG00000278718 ENSG00000167914 ENSG00000145649 ENSG00000204311 ENSG00000073605 PMC3133824__F2 Mechanisms for import and export of proteins to and from the nucleus ENSG00000198125 ENSG00000132341 PMC3133824__F1 Cytonuclear signaling pathways in MSNs PMC7716119__F4 Differentially expressed mRNA of the ceRNA network was significantly enriched, to create a meaningful MAPK and FoxO signaling pathway map ENSG00000087095 ENSG00000171105 ENSG00000179091 ENSG00000138798 ENSG00000127528 ENSG00000130159 ENSG00000168610 ENSG00000010671 ENSG00000145604 ENSG00000149311 ENSG00000170458 ENSG00000123374 ENSG00000135517 ENSG00000026103 PMC4344212__F4 Pathway-Based Analysis of Genome-Wide siRNA Screens Reveals the Regulatory Landscape of App Processing ENSG00000170608 ENSG00000262785 ENSG00000142192 ENSG00000169856 ENSG00000159593 ENSG00000182759 ENSG00000122859 ENSG00000164305 ENSG00000106331 ENSG00000150782 ENSG00000125820 ENSG00000143801 ENSG00000196549 ENSG00000121351 ENSG00000130675 ENSG00000205155 ENSG00000139515 ENSG00000182240 ENSG00000163623 ENSG00000152804 ENSG00000114315 PMC8570012__F1 Mesenchymal stem cells in cancer progression and anticancer therapeutic resistance ENSG00000163464 ENSG00000178860 ENSG00000169245 ENSG00000163739 ENSG00000138798 ENSG00000108700 ENSG00000168610 PMC9446437__F3 Systematic review of gastric cancer-associated genetic variants, gene-based meta-analysis, and gene-level functional analysis to identify candidate genes for drug development ENSG00000019991 ENSG00000291971 ENSG00000198793 ENSG00000168036 ENSG00000169242 ENSG00000146648 ENSG00000169231 PMC8226806__F2 Progenitor/Stem Cells in Vascular Remodeling during Pulmonary Arterial Hypertension ENSG00000178860 ENSG00000066468 ENSG00000107562 ENSG00000164690 ENSG00000204217 ENSG00000136826 ENSG00000121966 PMC11938631__F6 Mechanisms of Shh signaling pathway in maintaining BBB integrity ENSG00000164690 ENSG00000128602 PMC9601273__F4 Classical Angiogenic Signaling Pathways and Novel Anti-Angiogenic Strategies for Colorectal Cancer ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000121966 PMC11612781__F3 From sampling to simulating: Single-cell multiomics in systems pathophysiological modeling ENSG00000163421 ENSG00000146469 ENSG00000122877 ENSG00000179094 PMC11938631__F8 Major common pathways regulating BBB integrity after TBI and in AD ENSG00000198793 ENSG00000164690 ENSG00000100985 ENSG00000128602 PMC11938631__F3 Multifaceted roles of TGFB signaling in BBB integrity PMC9666724__F4 Functional and clinical characteristics of focal adhesion kinases in cancer progression ENSG00000169245 ENSG00000291971 ENSG00000108688 ENSG00000150630 PMC11938631__F5 Activation of the Wnt/Beta-catenin signaling pathway maintains the BBB integrity ENSG00000134982 ENSG00000168036 PMC9666724__F6 Functional and clinical characteristics of focal adhesion kinases in cancer progression ENSG00000196591 ENSG00000150457 ENSG00000146648 ENSG00000131023 PMC9601273__F3 Classical Angiogenic Signaling Pathways and Novel Anti-Angiogenic Strategies for Colorectal Cancer ENSG00000138798 ENSG00000112715 ENSG00000168610 ENSG00000146648 PMC4183521__F5 Neuroendocrine Humoral and Vascular Components in the Pressor Pathway for Brain Angiotensin II: A New Axis in Long Term Blood Pressure Control ENSG00000047410 ENSG00000137672 PMC7998619__F2 Viral immune evasion in the placenta utilized by cytomegalovirus (CMV) and Zika virus ENSG00000108691 ENSG00000213928 ENSG00000239732 ENSG00000088888 ENSG00000169429 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC9601273__F2 Classical Angiogenic Signaling Pathways and Novel Anti-Angiogenic Strategies for Colorectal Cancer ENSG00000120063 ENSG00000147649 ENSG00000081041 ENSG00000163739 ENSG00000112715 PMC9601273__F1 Classical Angiogenic Signaling Pathways and Novel Anti-Angiogenic Strategies for Colorectal Cancer ENSG00000291971 ENSG00000126353 ENSG00000112715 ENSG00000277363 PMC8861501__F7 Integrative Analysis of the lncRNA-Associated ceRNA Regulatory Network Response to Hypoxia in Alveolar Type II Epithelial Cells of Tibetan Pigs ENSG00000074800 ENSG00000111537 ENSG00000189060 PMC2683871__F6 p53-regulated pathway analysis using the Ingenuity Pathway Knowledge Base (IPKB) ENSG00000145632 ENSG00000152409 ENSG00000168209 ENSG00000198830 ENSG00000085117 ENSG00000109320 ENSG00000074319 ENSG00000196154 ENSG00000198300 ENSG00000178726 ENSG00000134480 ENSG00000080546 ENSG00000149968 ENSG00000055163 ENSG00000164938 ENSG00000163848 ENSG00000139289 ENSG00000112378 ENSG00000101138 ENSG00000175305 PMC4021575__F3 Ribosome assembly and Insulin signalling pathway ENSG00000171105 ENSG00000226275 ENSG00000090402 ENSG00000002330 ENSG00000026103 PMC1769521__F2 Senescence via tumor suppressor pathways ENSG00000168283 ENSG00000121068 ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000140464 PMC6943030__F2 Section from a pathway that describes the biosynthesis of Lewis-type epitopes by the bacterium Helicobacter pylori ENSG00000197487 PMC8625890__F8A Clinically Relevant Genes and Proteins Modulated by Tocotrienols in Human Colon Cancer Cell Lines: Systematic Scoping Review ENSG00000157554 ENSG00000002330 ENSG00000134982 ENSG00000164305 ENSG00000122008 PMC4948992__F3A Regulation of biomechanical signals by NFKB transcription factors in chondrocytes ENSG00000125538 ENSG00000007171 PMC2780914__F3 Transmigration causes differential expression of genes in the apoptosis pathway ENSG00000067900 ENSG00000148935 ENSG00000084774 ENSG00000276068 PMC7446622__F1 Inflammation during SARS-CoV-2 infection.SARS-CoV-2 invade host cells with angiotensin-converting enzyme2 (ACE2) receptors present on the cell surface membrane ENSG00000162711 ENSG00000172936 ENSG00000136869 PMC7446622__F4 Putative role of Gsk-3 in the SARS-CoV-2 replication and COVID-19 pathogenesis.Activated Gsk-3 phosphorylate the nucleocapsid protein of SARS-CoV-2 and support viral genome replication and transcription ENSG00000168036 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000079999 PMC7446622__F3 Glycogen synthase kinase-3: A putative target to combat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic ENSG00000110799 ENSG00000136869 PMC8838156__F1 Toll-like Receptor 4, Osteoblasts and Leukemogenesis; the Lesson from Acute Myeloid Leukemia ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC9099292__F7 Transcriptome Analysis Reveals the Molecular Response to Salinity Challenge in Larvae of the Giant Freshwater Prawn Macrobrachium rosenbergii ENSG00000164104 PMC3355540__F2 Nuclear receptors and photoreceptor differentiation in mice ENSG00000105392 ENSG00000263310 ENSG00000069667 PMC7476096__F4 Effect of miR-135a on the epithelial-mesenchymal transition (EMT) ENSG00000170558 ENSG00000102349 ENSG00000168036 PMC6697794__F8 Schematic diagram represents that leptin signaling-dependent activation of mTORC2/Phllp1/Akt pathway abrogates lysosomal function and negatively regulates macrophage defense during S ENSG00000081913 ENSG00000168610 PMC7476096__F3 Effects of miR-135a on cancer progression and relevant targets and signaling pathways ENSG00000253293 ENSG00000168283 ENSG00000134982 ENSG00000150907 ENSG00000102349 ENSG00000168036 ENSG00000040199 ENSG00000067900 ENSG00000196470 ENSG00000168610 ENSG00000146648 ENSG00000146587 PMC2855089__F2 NFKB Signaling Pathway ENSG00000102871 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC2643306__F1 Structure-function relationships in methionine adenosyltransferases PMC6984792__F8 Mechanism of action of ASB in UV-induced photo-damage in HaCaT cells ENSG00000125538 ENSG00000079999 PMC8468723__F3 NUB1 and FAT10 Proteins as Potential Novel Biomarkers in Cancer: A Translational Perspective ENSG00000132646 ENSG00000168610 PMC4515750__F1 Diversity and complexity of dicer dependent small RNA networks in animals ENSG00000100697 ENSG00000113360 ENSG00000123908 PMC4767488__F1 Inhibition of the Tcf/beta-catenin complex increases apoptosis and impairs adrenocortical tumor cell proliferation and adrenal steroidogenesis ENSG00000134982 ENSG00000050165 ENSG00000168036 ENSG00000104332 PMC9654300__F2 Aberrant B Cell Signaling in Autoimmune Diseases ENSG00000177455 ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000198793 ENSG00000136997 ENSG00000153064 ENSG00000175104 ENSG00000010671 ENSG00000198286 PMC3655383__F2 Importance of white adipose tissue (WAT)–skeletal muscle crosstalk in cancer associated cachexia (CAC) and/or lipotoxicity ENSG00000135218 ENSG00000144895 ENSG00000169047 ENSG00000123689 PMC8918699__F1 Large granular lymphocytic leukemia: a brief review ENSG00000185591 ENSG00000168040 ENSG00000168610 ENSG00000026103 PMC5374157__F1 Type I interferons (IFNs) and different other cytokines are essential for natural killer (NK) cell homeostasis and function ENSG00000150782 ENSG00000105397 ENSG00000164136 ENSG00000172936 ENSG00000105639 ENSG00000175104 ENSG00000142166 PMC7872201__F1 Targets of acetylation/deacetylation in metabolic pathways known to affect I/R injury ENSG00000073578 ENSG00000100412 ENSG00000142082 ENSG00000146701 PMC8766720__F6 MiR-27a-3p Targets GLP1R to Regulate Differentiation, Autophagy, and Release of Inflammatory Factors in Pre-Osteoblasts via the AMPK Signaling Pathway ENSG00000057663 PMC5610088__F1 Phospholipid biosynthetic pathways in Streptomyces ENSG00000198670 ENSG00000184207 PMC5763468__F2 MCF7-related generic pathway map ENSG00000149311 ENSG00000012048 ENSG00000171105 ENSG00000002330 ENSG00000198793 ENSG00000171848 ENSG00000171791 ENSG00000166851 ENSG00000146648 PMC5291233__F6 Impact of pridopidine treatment on BDNF signalling, AKT activation, and the glucocorticoid pathway ENSG00000168209 ENSG00000172216 ENSG00000100906 ENSG00000122877 ENSG00000198576 ENSG00000124762 PMC5043072__F3 Targeted proteomic approach in prostatic tissue: a panel of potential biomarkers for cancer detection ENSG00000004975 ENSG00000198053 ENSG00000070182 ENSG00000135439 ENSG00000134982 ENSG00000198793 ENSG00000186480 ENSG00000178209 ENSG00000187140 ENSG00000054654 ENSG00000103479 ENSG00000084676 ENSG00000197386 ENSG00000008300 ENSG00000119487 ENSG00000157764 ENSG00000138594 ENSG00000107863 ENSG00000197565 ENSG00000165059 ENSG00000157106 ENSG00000114993 ENSG00000067066 ENSG00000261371 ENSG00000143476 ENSG00000196218 ENSG00000178028 PMC5763468__F4 MCF7-specific signaling pathway network inferred by TILP model ENSG00000149311 ENSG00000012048 ENSG00000171105 ENSG00000002330 ENSG00000198793 ENSG00000171848 ENSG00000171791 ENSG00000166851 ENSG00000146648 PMC4060203__F1 Schematic showing the details of the estrogen pathway ENSG00000108786 ENSG00000203857 PMC4849044__F2 Schematic diagram illustrates the role of matrilin-3 in ECM modulation of cartilage ENSG00000170365 ENSG00000132031 ENSG00000154736 ENSG00000149968 ENSG00000125538 ENSG00000158859 PMC3094097__F3 Examples of cellular receptors that sense infection and cell death ENSG00000239732 ENSG00000189403 ENSG00000136869 PMC2393790__F3 Citrate cycle genes are up-regulated in the brains of nurse bees ENSG00000131473 ENSG00000073578 ENSG00000173599 ENSG00000105953 ENSG00000091140 ENSG00000062485 PMC155330__F7 slpr, encoding Drosophila MLK, is the MKKK for the Jun kinase pathway during dorsal closure in the fly ENSG00000070831 PMC9091111__F5 Curcumin treats endometriosis in mice by the HIF signaling pathway ENSG00000109320 ENSG00000138798 ENSG00000177606 ENSG00000112715 ENSG00000164305 ENSG00000132170 ENSG00000026103 PMC9091111__F4 Curcumin treats endometriosis in mice by the HIF signaling pathway ENSG00000178999 ENSG00000138798 ENSG00000198793 ENSG00000140505 ENSG00000196591 ENSG00000120889 ENSG00000168036 ENSG00000087586 ENSG00000108443 ENSG00000148344 ENSG00000112715 ENSG00000118777 ENSG00000164305 ENSG00000124762 ENSG00000129214 ENSG00000150907 ENSG00000125538 ENSG00000095303 ENSG00000136869 ENSG00000275565 ENSG00000132906 ENSG00000087245 ENSG00000161905 ENSG00000116044 ENSG00000148400 ENSG00000109320 ENSG00000131747 ENSG00000140465 ENSG00000073756 ENSG00000168610 ENSG00000007171 ENSG00000132170 ENSG00000177606 ENSG00000132646 ENSG00000100985 ENSG00000196689 ENSG00000146648 PMC3657702__F1 Age-related alteration of gene expression in the TCR signaling pathway ENSG00000110395 ENSG00000213658 ENSG00000117091 ENSG00000010810 ENSG00000163599 ENSG00000113263 PMC11580395__F2 Interaction between the sonic hedgehog signalling pathway and other molecular pathways ENSG00000106571 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000164690 ENSG00000104332 ENSG00000128602 PMC11580395__F1 SHH pathways in tumorigenesis and their types (canonical and non-canonical) ENSG00000064309 ENSG00000106571 ENSG00000134057 ENSG00000144857 ENSG00000164690 ENSG00000128602 PMC5438149__F7 Rho-associated coiled-coil containing kinases (ROCK) inhibitor, Y-27632, enhances adhesion, viability and differentiation of human term placenta-derived trophoblasts in vitro ENSG00000163914 ENSG00000137270 PMC3565545__F10 CHEK kinase pathway showing the role of CHEK proteins in cell cycle checkpoint control, and crosstalk with other pathways notably the P53 and BRCA pathways.Notes: Double circles indicate complex interactions involving multiple genes ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000113456 ENSG00000132646 ENSG00000123374 PMC11857725__F2 The metabolic pathway of tryptophan and phenylalanine in ADHD ENSG00000123454 ENSG00000141744 ENSG00000171759 PMC9249328__F8 Identification of VdASP F2‐interacting protein as a regulator of microsclerotial formation in Verticillium dahliae ENSG00000180210 ENSG00000009844 PMC11364484__F2 TGFB and BMP receptors and their signaling pathways ENSG00000107779 ENSG00000121989 ENSG00000170365 ENSG00000139567 ENSG00000204217 ENSG00000125968 PMC7808269__F5 c-Rel Is a Myeloid Checkpoint for Cancer Immunotherapy ENSG00000213928 ENSG00000162433 ENSG00000183486 ENSG00000157601 ENSG00000160710 ENSG00000010278 ENSG00000163737 ENSG00000230034 ENSG00000134321 ENSG00000188313 ENSG00000038427 ENSG00000244405 ENSG00000134326 ENSG00000136997 ENSG00000164400 ENSG00000140464 ENSG00000132109 ENSG00000108342 ENSG00000116717 ENSG00000125347 ENSG00000162654 ENSG00000276561 ENSG00000007171 ENSG00000138378 ENSG00000133048 ENSG00000156127 ENSG00000185201 ENSG00000160223 ENSG00000172936 ENSG00000111331 ENSG00000162692 ENSG00000019991 ENSG00000151014 ENSG00000171855 ENSG00000139572 ENSG00000152661 ENSG00000280962 ENSG00000101000 ENSG00000183625 ENSG00000010818 ENSG00000197272 ENSG00000099860 ENSG00000168811 ENSG00000118971 ENSG00000136859 ENSG00000292210 ENSG00000137801 ENSG00000277571 ENSG00000150782 ENSG00000109861 ENSG00000178573 ENSG00000188042 ENSG00000263528 ENSG00000125538 ENSG00000128052 ENSG00000141753 ENSG00000137265 ENSG00000108688 ENSG00000169508 ENSG00000236637 ENSG00000174125 ENSG00000148346 ENSG00000291431 ENSG00000140287 ENSG00000277804 ENSG00000162924 ENSG00000154760 ENSG00000205045 ENSG00000172183 ENSG00000115607 ENSG00000184979 ENSG00000112195 ENSG00000108691 ENSG00000065328 ENSG00000138135 ENSG00000115415 ENSG00000177606 ENSG00000135114 ENSG00000164136 ENSG00000100985 ENSG00000113302 ENSG00000115232 ENSG00000152518 PMC7808269__F4 c-Rel Is a Myeloid Checkpoint for Cancer Immunotherapy ENSG00000277336 ENSG00000102962 ENSG00000172322 ENSG00000187608 ENSG00000171049 ENSG00000196154 ENSG00000124875 ENSG00000121966 ENSG00000035720 ENSG00000171051 ENSG00000102879 ENSG00000077150 ENSG00000172216 ENSG00000163734 ENSG00000118520 ENSG00000143546 ENSG00000197635 ENSG00000119535 ENSG00000163220 ENSG00000129450 ENSG00000167552 ENSG00000277943 ENSG00000169245 ENSG00000171777 ENSG00000226275 ENSG00000108691 ENSG00000158714 ENSG00000123609 ENSG00000100985 ENSG00000162692 ENSG00000125245 PMC10506516__F6 Schematics of proposed pathway for beneficial effects of L-carnitine on lipid parameters ENSG00000157184 ENSG00000113161 PMC2597730__F7 Cascade between VEGFA, a direct target of BP1, and its downstream target genes in cell proliferation ENSG00000140992 ENSG00000157764 ENSG00000065361 ENSG00000132326 ENSG00000198125 ENSG00000127616 ENSG00000125968 ENSG00000104368 ENSG00000101425 PMC9234279__F6 Methyl Gallate Suppresses the Migration, Invasion, and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma Cells via the AMPK/NFKB Signaling Pathway in vitro and in vivo ENSG00000087245 ENSG00000100985 PMC7848207__F2 Mechanisms of action and signaling pathways of SIRT1 in diabetic nephropathy ENSG00000150907 ENSG00000086991 ENSG00000168036 ENSG00000096717 ENSG00000079999 PMC11667996__F3 EBV-Driven Oncogenesis: Manipulating MAPK Signaling and Apoptotic Pathways: EBV promotes tumorigenesis through the MAPK signaling pathway, manipulating host cellular mechanisms ENSG00000116106 ENSG00000291431 ENSG00000185591 PMC11830326__F6 Signaling pathways involved in repurposing drugs in cancer therapy ENSG00000112977 ENSG00000198793 ENSG00000168610 PMC11667996__F2 Oncogenic Role of H ENSG00000291971 PMC11667996__F1 Activation and signaling pathways of the MAPK Cascade: an overview of stimuli, cascades, and downstream targets: this detailed illustration outlines the four central signaling pathways within the MAPK framework: ERK5, ERK, JNK, and p38/MAPK ENSG00000185591 ENSG00000175104 ENSG00000184216 PMC8651430__F2 Recent Advances in the Endogenous Brain Renin-Angiotensin System and Drugs Acting on It ENSG00000130234 PMC6170679__F7 Model summarizing the proposed signaling events in the myeloid CXCR4 deletion mice ENSG00000111537 ENSG00000121966 ENSG00000026103 PMC11830326__F3 Targeting epithelial-mesenchymal transition signaling pathways with Dietary Phytocompounds and repurposed drug combinations for overcoming drug resistance in various cancers ENSG00000138795 ENSG00000168036 ENSG00000107485 ENSG00000184916 PMC11830326__F2 Targeting epithelial-mesenchymal transition signaling pathways with Dietary Phytocompounds and repurposed drug combinations for overcoming drug resistance in various cancers ENSG00000169554 ENSG00000168036 PMC11830326__F5 Dietary phytochemicals targeting Wnt, TGFB, JAK/STAT, NOTCH, PI3K, and TNFA signaling pathways involved in EMT transitions ENSG00000198793 ENSG00000107485 PMC9270757__F3 Regulatory function of DNA methylation mediated lncRNAs in gastric cancer ENSG00000088305 ENSG00000170558 ENSG00000097021 ENSG00000020633 ENSG00000168036 ENSG00000185591 ENSG00000146648 ENSG00000284944 PMC11830326__F4 Targeting epithelial-mesenchymal transition signaling pathways with Dietary Phytocompounds and repurposed drug combinations for overcoming drug resistance in various cancers ENSG00000169554 ENSG00000019549 ENSG00000168036 PMC6827018__F8 Schematic representation of the entire signaling pathway ENSG00000150457 PMC8589460__F1 Therapeutic strategies targeting Wnt/Beta-catenin signaling for colorectal cancer (Review) ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000136997 ENSG00000168036 PMC3807052__F1 Migration of opioid-containing immune cells and opioid release within inflamed tissue ENSG00000125538 ENSG00000169429 PMC3111743__F6 Correlation network among processes with activity modified by both OEA and KDS-5104 treatments is shown ENSG00000135218 ENSG00000026103 PMC7938465__F5 Re-analysis of 15 selected genes via KEGG pathway enrichment analysis ENSG00000184990 ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000136997 ENSG00000042286 ENSG00000112378 ENSG00000164305 PMC8306455__F5 Evasion of the Host Immune Response by Betaherpesviruses ENSG00000183735 ENSG00000164430 ENSG00000138798 ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000171791 ENSG00000168040 ENSG00000175104 ENSG00000146648 ENSG00000164342 PMC8306455__F4 Evasion of the Host Immune Response by Betaherpesviruses ENSG00000138798 ENSG00000198793 ENSG00000171791 ENSG00000168040 ENSG00000146648 PMC7938465__F3 Protein-protein interaction (PPI) network of DEGs ENSG00000164932 ENSG00000114200 ENSG00000113805 ENSG00000175003 ENSG00000198670 ENSG00000005187 ENSG00000145824 ENSG00000113600 ENSG00000112964 ENSG00000150656 ENSG00000131747 ENSG00000105697 ENSG00000100526 ENSG00000122787 ENSG00000116882 ENSG00000117650 ENSG00000118785 ENSG00000156970 ENSG00000164161 ENSG00000143476 ENSG00000175336 ENSG00000136872 ENSG00000019991 ENSG00000107562 ENSG00000165682 ENSG00000198077 ENSG00000109758 ENSG00000197408 ENSG00000160339 ENSG00000140505 ENSG00000255974 ENSG00000095596 ENSG00000072571 ENSG00000277893 ENSG00000164266 ENSG00000150625 ENSG00000112186 ENSG00000112299 ENSG00000101955 ENSG00000145708 ENSG00000135423 ENSG00000081041 ENSG00000114346 ENSG00000111713 ENSG00000188676 ENSG00000172425 ENSG00000198901 ENSG00000134057 ENSG00000171848 ENSG00000205364 PMC8306455__F3 Evasion of the Host Immune Response by Betaherpesviruses ENSG00000183735 ENSG00000172936 ENSG00000131323 ENSG00000175104 PMC8306455__F2 Evasion of the Host Immune Response by Betaherpesviruses ENSG00000183735 ENSG00000164430 PMC6018831__F3 Metabolic reconstruction of LSUCC0530 ENSG00000002330 ENSG00000122966 ENSG00000172005 ENSG00000116761 PMC7213295__F1 PI3K/AKT/mTOR/NFKB Pathway in Ovarian Cancer ENSG00000109452 ENSG00000198793 ENSG00000155792 ENSG00000167965 PMC156240__F1 Xu-5-P is the signal for the coordinated control of lipogenesis ENSG00000122966 PMC11172960__F4 Molecular targets of natural product-derived compounds for psoriasis treatment ENSG00000145604 ENSG00000162711 ENSG00000115415 ENSG00000173039 ENSG00000221869 ENSG00000096717 ENSG00000168610 ENSG00000115009 PMC11172960__F2 Putative molecular targets and their associated signaling pathways for psoriasis in keratinocytes ENSG00000162711 ENSG00000163568 ENSG00000165280 ENSG00000189403 ENSG00000096717 ENSG00000111816 ENSG00000168610 ENSG00000106546 PMC6801309__F1 An overview of myocardial energy substrate utilization ENSG00000157184 ENSG00000135218 PMC11172960__F1 Signaling pathways in psoriasis pathogenesis in keratinocytes ENSG00000169248 ENSG00000143546 ENSG00000102871 ENSG00000127191 ENSG00000073756 ENSG00000143556 ENSG00000168610 ENSG00000163702 ENSG00000169245 ENSG00000105397 ENSG00000115415 ENSG00000138755 ENSG00000162692 ENSG00000115009 PMC8027889__F1 AHR and its signaling pathway ENSG00000110711 ENSG00000291971 ENSG00000140505 ENSG00000106546 PMC2913337__F2 Cross talk of the Nodal/Cripto-1 signaling pathway with Wnt, hypoxia, Notch, Oct-4, and Nanog signaling pathways ENSG00000148400 ENSG00000156574 ENSG00000168036 ENSG00000130283 ENSG00000184344 ENSG00000155760 PMC4111689__F1 Targeting the Achilles’ heel of drug-resistant cancer stem cells ENSG00000144118 ENSG00000146648 PMC6401303__F6 It’s complicated… m6A-Dependent Regulation of Gene Expression in Cancer ENSG00000120833 ENSG00000198492 ENSG00000165819 PMC3570385__F1 Signal transduction pathway through TLR ENSG00000239732 ENSG00000102871 ENSG00000136869 ENSG00000168040 ENSG00000175104 ENSG00000164342 PMC9027306__F2 MST1R/RON Tyrosine Kinase in Cancer: Oncogenic Functions and Therapeutic Strategies ENSG00000168036 ENSG00000126778 ENSG00000159399 PMC7563658__F1 Canonical and non-canonical nuclear factor K (kappa)-light-chain-enhancer of activated B cells (NFKB) signalling pathways ENSG00000104856 ENSG00000173039 PMC3759646__F1 Molecular mechanisms and signaling pathways of angiotensin II-induced muscle wasting: potential therapeutic targets for cardiac cachexia ENSG00000169047 ENSG00000198793 ENSG00000140443 PMC2948541__F5 Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders ENSG00000174576 ENSG00000159388 ENSG00000150907 ENSG00000197632 ENSG00000163083 ENSG00000265972 ENSG00000162772 PMC6731550__F4 Intracellular pathways targeted by disease pathogenesis in FTLD ENSG00000123240 ENSG00000188021 ENSG00000284099 ENSG00000165280 ENSG00000283741 ENSG00000147894 PMC7666787__F7 Role of Tim-3 in breast cancer ENSG00000112715 ENSG00000168610 PMC7878551__F6 Hypothetical model for Gram-negative bacteria induced major innate immune response in horseshoe crabs ENSG00000175899 ENSG00000172936 PMC9368391__F1 RNA Sensors in Host Innate Response to Influenza Virus and Coronavirus Infections ENSG00000162711 ENSG00000124256 ENSG00000183735 ENSG00000088888 ENSG00000163565 ENSG00000172936 ENSG00000168404 ENSG00000285379 ENSG00000215301 ENSG00000164342 PMC7343516__F8 Schematic diagrams showing the potential mechanism in the protective effects of Epothilone B on LPS induced inflammatory bone destruction ENSG00000100985 ENSG00000168610 ENSG00000131196 ENSG00000143387 PMC9368391__F3 RNA Sensors in Host Innate Response to Influenza Virus and Coronavirus Infections ENSG00000162711 ENSG00000183735 ENSG00000088888 ENSG00000137275 ENSG00000125538 ENSG00000172936 ENSG00000106100 ENSG00000285379 ENSG00000164342 PMC6138031__F2 Illustrative model of the IFN signal transduction pathway ENSG00000111537 ENSG00000105397 ENSG00000115415 PMC2391069__F1 Overindulgence and metabolic syndrome: is FoxO1 a missing link? ENSG00000042832 ENSG00000005882 ENSG00000150907 ENSG00000285482 ENSG00000062282 PMC5192062__F2 IL-17 and IL-17 receptor family ENSG00000166090 ENSG00000056736 ENSG00000175104 ENSG00000163702 PMC2583496__F2 Global regulation of the E ENSG00000173039 ENSG00000153574 ENSG00000132693 PMC7657662__F2 Schematic depicting the complex I assembly pathway showing known mitochondrial disease genes in red, mtDNA-encoded subunits underlined and assembly factors in italics ENSG00000130414 ENSG00000131495 ENSG00000113845 ENSG00000166136 ENSG00000147123 ENSG00000139180 ENSG00000182511 ENSG00000128609 ENSG00000123545 ENSG00000184752 ENSG00000156170 ENSG00000110717 ENSG00000106603 ENSG00000177646 ENSG00000137806 ENSG00000160194 ENSG00000175606 ENSG00000147684 ENSG00000184983 ENSG00000292058 ENSG00000130159 ENSG00000004779 ENSG00000165264 ENSG00000178127 ENSG00000101247 ENSG00000184857 ENSG00000267855 ENSG00000183648 ENSG00000171204 ENSG00000137038 ENSG00000136521 ENSG00000109390 ENSG00000224877 ENSG00000213619 ENSG00000065518 ENSG00000151366 ENSG00000186010 ENSG00000099795 ENSG00000119013 PMC3321461__F1 Proposed mechanism for overcoming HNSCC resistance to EGFR antagonists using PI3kinase/Akt/mTOR and NFKB-IL6-STAT3 pathway inhibitors ENSG00000168610 ENSG00000146648 PMC2694580__F2 Biological actions of isoprenoids ENSG00000070831 PMC6605362__F1 Schematic showing methionine metabolism reactions ENSG00000116984 PMC7657662__F4 Schematic depicting the complex III assembly pathway showing known mitochondrial disease genes in red, mtDNA-encoded subunits underlined and assembly factors in italics ENSG00000169021 ENSG00000140740 ENSG00000179091 ENSG00000156467 ENSG00000166278 ENSG00000010256 ENSG00000182511 ENSG00000164405 ENSG00000127540 ENSG00000011295 ENSG00000186687 ENSG00000137288 ENSG00000204922 ENSG00000184076 PMC7657662__F3 Schematic depicting the complex II assembly pathway showing known mitochondrial disease genes in red and assembly factors in italics ENSG00000205138 ENSG00000143252 ENSG00000182511 ENSG00000073578 ENSG00000117118 ENSG00000154079 ENSG00000196636 ENSG00000167985 PMC7657662__F6 Schematic depicting the complex V (F1F0-ATPase) assembly pathway showing known mitochondrial disease genes in red, mtDNA-encoded proteins underlined and assembly factors in italics ENSG00000180210 ENSG00000120868 ENSG00000123268 PMC7657662__F5 Schematic depicting the complex IV assembly pathway showing known mitochondrial disease genes in red, mtDNA-encoded proteins underlined and assembly factors in italics ENSG00000183978 ENSG00000163626 ENSG00000181061 ENSG00000138495 ENSG00000178741 ENSG00000166260 ENSG00000240230 ENSG00000178449 ENSG00000187118 ENSG00000136463 ENSG00000229833 ENSG00000006695 ENSG00000146066 ENSG00000127184 ENSG00000131174 ENSG00000168275 ENSG00000189043 ENSG00000106603 ENSG00000144120 ENSG00000133983 ENSG00000284194 PMC4845178__F1 Dormancy programs and their potential use in patient treatment ENSG00000125398 ENSG00000175745 PMC4637164__F1 Activation of the complement cascade and its role in tumorigenesis ENSG00000039537 ENSG00000009724 ENSG00000113600 ENSG00000291559 ENSG00000244731 PMC4198062__F8 Possible mechanisms by which phosphorylation of PAGE4 at T51 could potentiate the transactivation of c-Jun but weaken its affinity for c-Jun ENSG00000101951 ENSG00000163349 PMC9667740__F1 Membranous nephropathy: Clearer pathology and mechanisms identify potential strategies for treatment ENSG00000291559 ENSG00000005108 ENSG00000166033 PMC5527958__F1 RTK activation ENSG00000157764 ENSG00000143815 ENSG00000198793 PMC4026364__F1 Tumor Suppressor p53 and Estrogen Receptors in Nuclear–Mitochondrial Communication ENSG00000078237 ENSG00000284194 PMC3635737__F8 CCDC22 deficiency in humans blunts activation of proinflammatory NFKB signaling ENSG00000173163 ENSG00000101997 ENSG00000169019 PMC5173152__F6 Wnt/Beta-catenin pathway transactivates microRNA-150 that promotes EMT of colorectal cancer cells by suppressing CREB signaling ENSG00000138795 ENSG00000168036 PMC7462931__F7 Hypothesis how decreased expression of glucose transporters in brain leading to a decreased intracellular d-glucose concentration in neurons may promote the emergence of AD ENSG00000142192 ENSG00000147162 ENSG00000198408 PMC7100557__F2 MERS-CoV inhibits innate antiviral signaling ENSG00000213928 ENSG00000088888 ENSG00000107201 ENSG00000164342 PMC7947863__F2 LncRNAs regulate CRC metastasis through protein binding ENSG00000122566 ENSG00000165119 ENSG00000174013 ENSG00000198793 ENSG00000168036 ENSG00000196470 PMC11492922__F3 Enriched KEGG terms and PPI network highlight upregulated genes involved in immune response and inflammation ENSG00000002330 ENSG00000058085 ENSG00000070831 ENSG00000179091 ENSG00000169047 ENSG00000043462 ENSG00000177455 ENSG00000012048 ENSG00000103479 ENSG00000111796 ENSG00000069482 ENSG00000186716 ENSG00000006327 ENSG00000291918 ENSG00000135919 PMC3137772__F2 De novo biosynthesis of dolichol phosphate in human ENSG00000197429 ENSG00000117682 ENSG00000128039 PMC2735334__F1 Carcinogenesis of Bcr-Abl in CML ENSG00000002330 ENSG00000186716 ENSG00000171791 PMC8172611__F9 Glucocappasalin Induces G2/M-Phase Arrest, Apoptosis, and Autophagy Pathways by Targeting CDK1 and PLK1 in Cervical Carcinoma Cells ENSG00000198793 ENSG00000166851 ENSG00000057663 PMC6478123__F2 Regulation of fatty acid oxidation, mevalonate pathway, and arachidonic acid metabolism by p53 ENSG00000152782 ENSG00000131473 ENSG00000134324 ENSG00000275565 ENSG00000026103 PMC2945811__F1 FA-regulated ICL repair ENSG00000131944 ENSG00000175054 ENSG00000164053 ENSG00000187790 ENSG00000276787 PMC12183059__F1 Molecular mechanisms of ferroptosis ENSG00000168003 ENSG00000161905 ENSG00000151012 ENSG00000196839 ENSG00000078668 ENSG00000167468 ENSG00000197429 ENSG00000111684 ENSG00000115107 ENSG00000079999 PMC3924162__F2 Signaling pathways in PCSCs ENSG00000168283 ENSG00000106571 ENSG00000148400 ENSG00000138798 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC3698976__F2 Methionine metabolism: transmethylation pathway PMC5064220__F7 Signaling network connecting RAS and mir-200 regulates apoptosis and EMT in cancer cells ENSG00000169554 ENSG00000177606 ENSG00000185591 ENSG00000171791 PMC5075711__F1 Formal modeling and analysis of ERA associated Biological Regulatory Network in breast cancer ENSG00000012048 ENSG00000169047 ENSG00000146648 ENSG00000140443 PMC9039220__F3 Challenges and Opportunities Associated With Platelets in Pancreatic Cancer ENSG00000148400 ENSG00000170558 ENSG00000171791 ENSG00000100985 PMC3743449__F5 Illustration of the hypoxia-inducible factor (HIF) activation pathway, highlighting hydroxylation and acetylation of HIF-1A depending on cellular oxygen tension, that is, normoxia and hypoxia ENSG00000019991 ENSG00000134086 ENSG00000163235 ENSG00000138798 ENSG00000125538 ENSG00000198793 PMC3743449__F4 Classical example of NFKB is the heterodimer of p50 and p65 and the classical activation pathway entails the release from its association with an inhibitory molecule of the IKB family ENSG00000111537 ENSG00000125538 ENSG00000056558 ENSG00000165280 ENSG00000162692 PMC7459646__F7 Effect of parental Se nutrition on the methionine cycle and transsulfuration pathway in the progeny of rainbow trout ENSG00000116984 PMC4508672__F2 HSV-I and the cellular DNA damage response ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000163961 ENSG00000144554 ENSG00000112130 PMC6256264__F7 Schematic summary of molecular mechanisms for duhuo jisheng decoction (DHJSD) on the lower back pain (LBP) caused by Bi Zheng ENSG00000163914 ENSG00000177606 ENSG00000168036 ENSG00000121966 PMC22464__F5 Metabolic reaction network analyzed from the human erythrocyte containing 29 metabolites and the related 51 fluxes (37 internal and 14 exchange fluxes) ENSG00000167900 PMC2784255__F1 Examination of Tetrahydrobiopterin Pathway Genes in Autism ENSG00000122966 ENSG00000171759 ENSG00000150787 ENSG00000137880 ENSG00000116096 ENSG00000166228 PMC3785791__F1 Abbreviated pathway to illustrate cGMP production and its role in oocyte meiotic arrest ENSG00000172572 ENSG00000159899 PMC7212408__F3 Notch signaling activity and Hippo pathway in BCSCs ENSG00000114978 ENSG00000150457 ENSG00000131023 PMC7212408__F2 Activation of MAPK signaling pathway in BCSCs ENSG00000280962 ENSG00000138798 ENSG00000019549 ENSG00000107485 ENSG00000178691 ENSG00000146648 PMC555938__F6 The metabolic shift pathway of yeast Saccharomyces cerevisiae according to the dynamic regulatory modeling in Table 2 ENSG00000284774 PMC555938__F5 Pathway of circadian regulatory system of Arabidopsis thaliana according to the dynamic regulatory modeling in Table 1 ENSG00000163435 PMC8113651__F2 Effect of autophagy modulation on HIV-1 infection ENSG00000094631 ENSG00000177169 ENSG00000261832 ENSG00000196455 ENSG00000143398 ENSG00000165527 ENSG00000145782 ENSG00000057663 ENSG00000168010 PMC7420839__F9 Retinoic acid synthesis and autoregulation mediate zonal patterning of vestibular organs and inner ear morphogenesis ENSG00000184254 ENSG00000003137 ENSG00000121039 PMC8113651__F1 HIV-1 modulation of autophagy during early infection and viral non-productive bystander cell contact, and in persistent infected cells/tissues ENSG00000142655 ENSG00000198793 ENSG00000141564 ENSG00000165527 ENSG00000057663 PMC9653672__F6 Analysis of RIOK2 Functions in Mediating the Toxic Effects of Deoxynivalenol in Porcine Intestinal Epithelial Cells ENSG00000185591 ENSG00000058729 PMC555938__F8 The pathway of metabolic shift regulatory system of yeast Saccharomyces cerevisiae in Fig ENSG00000284774 ENSG00000169299 PMC8646547__F2 Suppressor of Cytokine Signalling family of proteins and their potential impact on COVID‐19 disease progression ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000136869 ENSG00000125347 ENSG00000276561 ENSG00000164342 PMC555938__F7 Pathway of circadian regulatory system of Arabidopsis thaliana in Fig ENSG00000163435 PMC9069765__F8 EIF4A3-induced circTOLLIP promotes the progression of hepatocellular carcinoma via the miR-516a-5p/PBX3/EMT pathway ENSG00000132031 ENSG00000163661 PMC7918761__F1 Methionine cycle facilitates re-methylation of homocysteine to methionine via methionine synthase (MTR) and betaine-homocysteine S-methyltransferase (BHMT) enzymes ENSG00000124275 ENSG00000116761 ENSG00000116984 PMC8700621__F1 Transcriptome Analysis of Induced Pluripotent Stem Cells and Neuronal Progenitor Cells, Derived from Discordant Monozygotic Twins with Parkinson’s Disease ENSG00000095585 ENSG00000080007 PMC9655409__F8 Neuromedin S Regulates Steroidogenesis through Maintaining Mitochondrial Morphology and Function via NMUR2 in Goat Ovarian Granulosa Cells ENSG00000132911 ENSG00000069482 ENSG00000150457 ENSG00000131023 PMC7140344__F1 Melatonin: new insights on its therapeutic properties in diabetic complications ENSG00000169047 ENSG00000198793 ENSG00000158828 ENSG00000112715 ENSG00000142082 PMC8700621__F5 Transcriptome Analysis of Induced Pluripotent Stem Cells and Neuronal Progenitor Cells, Derived from Discordant Monozygotic Twins with Parkinson’s Disease ENSG00000107859 ENSG00000154764 ENSG00000128917 ENSG00000152208 PMC8700621__F4 Transcriptome Analysis of Induced Pluripotent Stem Cells and Neuronal Progenitor Cells, Derived from Discordant Monozygotic Twins with Parkinson’s Disease ENSG00000175054 ENSG00000107859 ENSG00000122877 ENSG00000198576 ENSG00000152208 ENSG00000135111 ENSG00000164093 ENSG00000164532 ENSG00000117407 ENSG00000159556 PMC6611507__F4 Emerging role of human cytomegalovirus infection in human carcinogenesis: a review of current evidence and potential therapeutic implications ENSG00000275385 ENSG00000138798 ENSG00000136997 ENSG00000007171 PMC4992466__F1 Pathways involved in physiological and in the pathological cardiac hypertrophy of calcific aortic valve disease (CAVD) ENSG00000198793 PMC6090955__F1 Overview of the IDO metabolic pathway ENSG00000188676 PMC8998447__F1 Nutraceuticals as Modulators of Autophagy: Relevance in Parkinson’s Disease ENSG00000177169 ENSG00000198793 ENSG00000005893 ENSG00000145782 ENSG00000057663 PMC6090955__F3 Regulation, function, and targeting of IDO1 in cancer ENSG00000157404 ENSG00000134982 ENSG00000163599 ENSG00000198793 ENSG00000172936 ENSG00000106546 PMC2593438__F7 AKT reduces the growth-inhibitory function of TGFB1 ENSG00000136929 ENSG00000185215 ENSG00000143126 ENSG00000149600 ENSG00000173039 ENSG00000184083 PMC10453526__F2 Nodes and tracks of the cholinergic anti-inflammatory pathway ENSG00000150782 ENSG00000168610 PMC6533757__F3 Immunosuppressive effect of the tumor microenvironment ENSG00000107562 ENSG00000169429 PMC4926737__F2 Disruption of postsynaptic differentiation pathway by muscle-specific kinase (MuSK) autoantibodies ENSG00000134569 ENSG00000030304 PMC5901981__F3 Protein Kinase C: Perfectly Balanced ENSG00000127445 ENSG00000105401 ENSG00000166278 PMC7098175__F5 Antitumor mechanism of Tan I ENSG00000198793 ENSG00000123374 ENSG00000168610 PMC3875633__F4 Invasion gene signaling networks (GSNs) of (A) chronic CNT-exposed and (B) chronic asbestos-exposed MeT5A cells ENSG00000133110 ENSG00000008516 ENSG00000115457 ENSG00000173039 ENSG00000087586 ENSG00000124664 ENSG00000146648 PMC7279300__F2 Signaling cascade of Dectin-1 ENSG00000104856 ENSG00000162711 ENSG00000187796 ENSG00000197943 PMC9603851__F1 TLR4-Pathway-Associated Biomarkers in Subarachnoid Hemorrhage (SAH): Potential Targets for Future Anti-Inflammatory Therapies ENSG00000157625 ENSG00000136869 ENSG00000184216 PMC1751079__F1 Inhibitory signals of the Toll-like receptor (TLR)4-induced MyD88-dependent signaling pathway ENSG00000170458 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000185591 ENSG00000185187 ENSG00000175104 ENSG00000184216 ENSG00000076604 ENSG00000132341 PMC8039377__F1 Molecular cascades that create epigenetic memory in HSCs ENSG00000161647 ENSG00000149311 ENSG00000084093 ENSG00000164430 ENSG00000111537 ENSG00000004455 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000285379 ENSG00000164342 PMC2446520__F1 The GNB/LNB pathway and related enzymes ENSG00000069482 PMC4357331__F1 One-carbon metabolism and methotrexateMTX enters the cell via the reduced folate carrier (RFC) by using an endocytic pathway activated by a folate receptor (FOLR [A, ƴ]) (a) (; ) ENSG00000284320 ENSG00000228716 ENSG00000100714 ENSG00000124275 ENSG00000035928 ENSG00000116984 PMC5350518__F8 Proposed molecular model of VCAM-1 regulation in ccRCC-VHL–expressing cells ENSG00000104856 ENSG00000134086 ENSG00000173039 ENSG00000162924 ENSG00000162692 PMC9081430__F1 Stat3 Signaling Pathway: A Future Therapeutic Target for Bone-Related Diseases ENSG00000178860 ENSG00000125538 ENSG00000168610 ENSG00000131196 PMC10919760__F3 Targeted and immunotherapeutic agents screened in GC PDX and PDO models ENSG00000175054 ENSG00000019991 ENSG00000066468 ENSG00000164879 ENSG00000281324 ENSG00000106571 ENSG00000162337 ENSG00000134982 ENSG00000166813 ENSG00000128602 ENSG00000146648 PMC10931375__F6 miRNAs targeting different components of the WNT signaling pathway to inhibit tumorigenicity ENSG00000134982 ENSG00000168036 ENSG00000099194 ENSG00000177283 PMC10931375__F5 miRNAs targeting different components of the WNT signaling pathway to promote tumorigenicity ENSG00000134982 ENSG00000168036 PMC4539617__F6 Cross talk between the bombesin neuropeptide receptor and Sonic hedgehog pathways in small cell lung carcinoma ENSG00000163914 ENSG00000164690 ENSG00000128602 PMC5700476__F7 NFKB signaling pathway is activated by TLR3/TLR4 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC6375884__F3 A schematic representation of main processes involved in rice drought memory response ENSG00000105722 ENSG00000136997 PMC9656902__F2 Influence of Long Non-Coding RNA in the Regulation of Cancer Stem Cell Signaling Pathways ENSG00000133937 ENSG00000148400 ENSG00000170558 ENSG00000136997 ENSG00000273529 ENSG00000253352 ENSG00000133961 ENSG00000114315 PMC9656902__F5 Influence of Long Non-Coding RNA in the Regulation of Cancer Stem Cell Signaling Pathways ENSG00000180447 ENSG00000128602 ENSG00000159399 PMC9656902__F4 Influence of Long Non-Coding RNA in the Regulation of Cancer Stem Cell Signaling Pathways ENSG00000088305 ENSG00000124766 ENSG00000182985 ENSG00000168610 PMC9656902__F3 Influence of Long Non-Coding RNA in the Regulation of Cancer Stem Cell Signaling Pathways ENSG00000162552 ENSG00000154764 ENSG00000078399 ENSG00000171634 ENSG00000168036 ENSG00000134245 ENSG00000135373 PMC5795986__F3 Signaling pathways for melanin inhibition by NSC-CM ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC7681076__F4 Proteaphagy: selective autophagy of inactive proteasomes ENSG00000163902 ENSG00000114520 PMC3839643__F1 Mammalian target of rapamycin (mTOR) -centric view of nutrient sensing for the induction of forkhead box P3 (FOXP3) ENSG00000198793 ENSG00000049768 ENSG00000168610 PMC12254190__F5 MiR-152 in hematologic malignancies, including multiple myeloma (A), AML-NPM1 (B), diffuse large B-cell lymphoma (C), non-Hodgkin lymphoma (D), chronic myeloid leukemia (E), and acute lymphoblastic leukemia (F) ENSG00000141867 PMC140043__F8 RelB is required for Peyer’s patch development: differential regulation of p52–RelB by lymphotoxin and TNF ENSG00000104856 ENSG00000226275 ENSG00000173039 ENSG00000111321 PMC3839643__F3 Enzymes that catabolize or use essential amino acids ENSG00000129596 ENSG00000060982 ENSG00000140287 ENSG00000171759 ENSG00000084110 ENSG00000118520 ENSG00000105552 ENSG00000007171 PMC11216939__F2 Interplay between the PI3K/AKT pathway and circadian rhythm regulators ENSG00000105516 PMC10670053__F1 Most common signalling pathways active in muscle and adipocytes during cancer-associated cachexia ENSG00000198793 ENSG00000128342 PMC5141640__F3 Ischemic stroke induces systemic immunosuppression mediated by several factors ENSG00000145321 ENSG00000149295 PMC5482702__F2 Hypoxia signalling pathway in haematological malignancies ENSG00000134086 ENSG00000138798 ENSG00000136997 PMC5326762__F2 Pathways of HIF-1A and its target genes involved in retinal neuroprotection ENSG00000134086 ENSG00000148926 ENSG00000169047 ENSG00000079999 PMC8892079__F1 Structural basis for dysregulation of aminolevulinic acid synthase in human disease ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000188690 PMC3390419__F1 Caspases and Kinases in a Death Grip ENSG00000171791 ENSG00000168040 ENSG00000026103 PMC6896486__F7 Exacerbation between G6PD dysfunction and neuroinflammation mediated chronic neurodegeneration ENSG00000136869 PMC11758808__F5 Biosynthesis of ncAAs ENSG00000152193 ENSG00000179988 ENSG00000076662 PMC6279243__F5 Identification of Key Differentially Expressed MicroRNAs in Cancer Patients Through Pan-cancer Analysis ENSG00000117020 ENSG00000160867 ENSG00000169047 ENSG00000068383 ENSG00000077782 ENSG00000118971 ENSG00000184481 PMC2279152__F1 Apoptosis signalling pathways ENSG00000120868 ENSG00000171791 ENSG00000168040 ENSG00000164305 ENSG00000115317 PMC7681076__F6 Pexophagy in yeast and mammals ENSG00000149311 ENSG00000142655 ENSG00000188554 ENSG00000124587 ENSG00000288217 ENSG00000108733 ENSG00000164751 ENSG00000034693 ENSG00000135093 PMC4212313__F1 B cell receptor signalling pathway controls B-cell fate and function ENSG00000010810 ENSG00000197943 ENSG00000010671 PMC6105693__F8 Transforming Growth Factor Beta Signaling in Dendritic Cells Is Required for Immunotolerance to Sperm in the Epididymis ENSG00000203747 ENSG00000019582 ENSG00000161905 ENSG00000179344 ENSG00000197992 ENSG00000043462 ENSG00000162692 ENSG00000145850 ENSG00000166211 PMC3655867__F2 Leptin deficiency disturbs the insulin signaling pathway JAK2/IRS/PI3K/AKT/AMPK and triggers diabetes ENSG00000168610 PMC6615313__F6 Metabolic context of the reconstructed σ54 regulons in Clostridiales species ENSG00000188158 ENSG00000105379 PMC9119167__F4 Studies in the antiviral molecular mechanisms of 25-hydroxycholesterol: Disturbing cholesterol homeostasis and post-translational modification of proteins ENSG00000110048 ENSG00000141458 ENSG00000160179 ENSG00000159335 PMC9119167__F2 Studies in the antiviral molecular mechanisms of 25-hydroxycholesterol: Disturbing cholesterol homeostasis and post-translational modification of proteins ENSG00000110921 ENSG00000138135 ENSG00000036530 ENSG00000197429 ENSG00000135929 PMC7288675__F2 Regulation of the microbiota in adaptive immunity ENSG00000162594 PMC11034608__F7 p38 MAPK inhibitor SB202190 suppresses ferroptosis in the glutamate-induced retinal excitotoxicity glaucoma model ENSG00000151012 ENSG00000167468 PMC7269988__F2 ER stress and the activation of the three UPR pathways ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC8720965__F4 Disorders of Sex Development of Adrenal Origin ENSG00000151632 ENSG00000127948 PMC6528915__F2 Overview for the regulatory mechanisms upstream and downstream of ZEB1‐AS1 in cancer progression ENSG00000087245 ENSG00000168283 ENSG00000123374 ENSG00000100985 ENSG00000168610 PMC7249489__F3 Signaling Pathways in Leukemic Stem Cells ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC4638170__F3 Gaining insights into diabetic cardiomyopathy from Drosophila ENSG00000075142 ENSG00000120438 ENSG00000026103 PMC7249489__F5 Signaling Pathways in Leukemic Stem Cells ENSG00000105329 PMC7016461__F5 KEGG enrichment analysis of the hub genes ENSG00000142192 ENSG00000185591 PMC7249489__F2 Signaling Pathways in Leukemic Stem Cells ENSG00000155792 PMC4303147__F4 Dominant negative LMP1 inhibits proliferation of CAEBV T cells ENSG00000104856 ENSG00000102871 ENSG00000276561 PMC6412627__F1 Synthesis of triacylglycerol (TAG) ENSG00000131446 ENSG00000168282 ENSG00000158669 ENSG00000285482 ENSG00000198670 ENSG00000026652 ENSG00000160216 ENSG00000186281 ENSG00000128268 ENSG00000062282 PMC6412627__F3 Regulation of the expression and cleavage of sterol regulatory element-binding protein-1c (SREBP-1c) and the transcriptional activation of the acyl-CoA:glycerol-sn-3-phosphate acyltransferase1 (GPAT1) gene ENSG00000169047 PMC6154995__F7 Heme-dependent feedback inhibition of ALAS in the heme biosynthetic pathway ENSG00000144410 ENSG00000066926 ENSG00000126088 ENSG00000188690 PMC3591604__F2 GPI anchor synthesis ENSG00000275600 ENSG00000142892 ENSG00000143315 ENSG00000108474 ENSG00000135845 ENSG00000100564 ENSG00000136908 ENSG00000197121 ENSG00000165282 PMC3865857__F2 Main enzymes and G protein-coupled receptors in the cyclooxygenase pathway ENSG00000122420 ENSG00000050628 ENSG00000160013 ENSG00000125384 ENSG00000168229 ENSG00000124212 ENSG00000073756 ENSG00000160951 PMC2910015__F4 General view of the species-specific regulation of histone homeostasis ENSG00000149308 PMC3865857__F1 Conversion of ω6 and ω3 series PUFA by metabolic enzymes and interaction with de novo fatty acid synthesis ENSG00000134824 ENSG00000149485 ENSG00000197977 ENSG00000169710 ENSG00000103150 ENSG00000099194 PMC11681754__F7 Potential mechanism of LPL-RH in salvaging bone calcium loss in OVX rats ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000131196 PMC7352853__F2 Sphingolipids implicated in pulmonary fibrosis, their structure, and metabolizing enzymes ENSG00000139624 ENSG00000063176 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000143753 ENSG00000119537 ENSG00000143418 PMC9325518__F1 Role and mechanism of noncoding RNAs in regulation of metabolic reprogramming in hepatocellular carcinoma ENSG00000131914 ENSG00000074800 ENSG00000198793 ENSG00000136997 ENSG00000187772 ENSG00000140443 PMC8327449__F3 PSPC1 is a new contextual determinant of aberrant subcellular translocation of oncogenes in tumor progression ENSG00000177426 PMC7352853__F6 Role of lysophosphatidic signaling via lysophosphatidic acid receptors in pulmonary fibrosis ENSG00000163914 ENSG00000198670 PMC3785471__F2 Host Response to Respiratory Bacterial Pathogens as Identified by Integrated Analysis of Human Gene Expression Data ENSG00000067066 ENSG00000168066 ENSG00000100906 ENSG00000142230 ENSG00000153201 ENSG00000116030 ENSG00000170035 ENSG00000062485 PMC9508608__F1 Methionine restriction - Association with redox homeostasis and implications on aging and diseases ENSG00000116649 ENSG00000102172 PMC9584741__F4 lncRNA IL-17RA-1 Attenuates LPS-Induced Sepsis via miR-7847-3p/PRKCG-Mediated MAPK Signaling Pathway ENSG00000277753 ENSG00000113492 ENSG00000266265 ENSG00000104967 ENSG00000152689 ENSG00000198626 ENSG00000276776 ENSG00000069431 ENSG00000148204 ENSG00000134853 ENSG00000037280 ENSG00000174611 ENSG00000182463 ENSG00000160221 ENSG00000167419 PMC7098175__F3 Antitumor mechanism of CT ENSG00000002330 ENSG00000168036 ENSG00000142082 ENSG00000168610 ENSG00000159399 PMC7098175__F2 Antitumor mechanism of Tan IIA ENSG00000145604 ENSG00000002330 ENSG00000144895 ENSG00000148400 ENSG00000163599 ENSG00000198793 ENSG00000168036 ENSG00000100985 ENSG00000168610 PMC7397204__F2 PI3K/Akt/mTOR signaling and its interaction with PTEN ENSG00000002330 ENSG00000169047 ENSG00000123374 ENSG00000051180 ENSG00000138092 PMC11042502__F2 Fructose impairs fat oxidation: Implications for the mechanism of western diet-induced NAFLD ENSG00000157184 ENSG00000117054 ENSG00000135218 ENSG00000138029 ENSG00000115361 ENSG00000122971 ENSG00000177646 ENSG00000127884 PMC9203892__F3 TIGIT as a Promising Therapeutic Target in Autoimmune Diseases ENSG00000181847 ENSG00000134982 ENSG00000150637 PMC8233504__F7 Genomic Architecture of Adaptation to Larval Malnutrition Points to a Trade-off with Adult Starvation Resistance in Drosophila ENSG00000103266 ENSG00000105401 ENSG00000102081 ENSG00000136997 ENSG00000164327 ENSG00000139726 ENSG00000119912 ENSG00000115540 PMC11040290__F1 Emerging role of galectin 3 in neuroinflammation and neurodegeneration ENSG00000153208 ENSG00000026508 ENSG00000027697 PMC4061222__F1 Roles of Wnt5a in cancer metastasis- (A) promoting and (B) suppressive processes ENSG00000169071 ENSG00000181788 ENSG00000168036 ENSG00000136869 ENSG00000165527 PMC2268796__F6 The signaling pathways regulating cell cycle and differentiation in tumor cells in response to shear stress ENSG00000170365 ENSG00000134057 PMC4109802__F2 Fibroblast growth factor-2 signaling in neurogenesis and neurodegeneration ENSG00000091972 ENSG00000077782 PMC9305269__F4 Effect of a Functional Phospholipid Metabolome-Protein Association Pathway on the Mechanism of COVID-19 Disease Progression ENSG00000100422 ENSG00000147869 ENSG00000173599 PMC5578430__F1 Innate immune escape by Dengue and West Nile viruses ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000121060 ENSG00000276561 PMC8278114__F6 Pro‐inflammatory signals induce 20A‐HSD expression in myometrial cells: A key mechanism for local progesterone withdrawal ENSG00000177606 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC7729028__F4 MEKK3–MEK5–ERK5–KLF2/4 signalling pathway ENSG00000070831 ENSG00000125538 ENSG00000127528 ENSG00000136869 ENSG00000136826 ENSG00000158859 PMC4632280__F7 RAC3 regulates cellular senescence and aging ENSG00000169750 ENSG00000198793 ENSG00000096717 PMC1698527__F10 Model for the transduction of DNA damage signals to the splicing machinery ENSG00000149311 ENSG00000175054 ENSG00000165632 ENSG00000130699 ENSG00000147133 PMC9684653__F3 Targeting the MDM2-p53 pathway in dedifferentiated liposarcoma ENSG00000149311 ENSG00000198793 ENSG00000087586 PMC4384662__F4A PI3K in cancer: divergent roles of isoforms, modes of activation, and therapeutic targeting ENSG00000177455 ENSG00000070831 ENSG00000186716 ENSG00000146648 PMC5640931__F2 The mathematical model ENSG00000134982 ENSG00000173599 ENSG00000168036 PMC2964935__F5 PAR Proteins: Fundamental Players in Animal Cell Polarization ENSG00000156299 ENSG00000163914 ENSG00000188487 ENSG00000133961 PMC3196148__F9 Working model for the ATF4-dependent and c-JUN-dependent AA signaling pathways ENSG00000128272 ENSG00000144895 PMC9445622__F1 Akt isoforms in the immune system PMC3209670__F3 mTOR signaling pathway affected by pollen feeding or varroa parasitism ENSG00000157764 ENSG00000102034 ENSG00000164327 PMC4595834__F7 Comparison of carbon-sulfur and carbon-amine bond in therapeutic drug: 4Beta-S-aromatic heterocyclic podophyllum derivatives display antitumor activity ENSG00000149311 ENSG00000175054 ENSG00000168040 PMC7177758__F1 JNK (C-Jun N-terminal kinase) substrates that regulate the mitochondrial apoptotic pathway ENSG00000002330 ENSG00000078747 ENSG00000104081 PMC7177758__F3 Positive feedback loops in apoptosis PMC9508608__F3 Methionine restriction - Association with redox homeostasis and implications on aging and diseases ENSG00000128272 ENSG00000181019 ENSG00000105550 ENSG00000198793 ENSG00000005381 ENSG00000096717 PMC4908701__F5 Curcumin regulated signaling networks ENSG00000142627 ENSG00000105329 ENSG00000070831 ENSG00000065361 ENSG00000105647 ENSG00000151929 ENSG00000099942 ENSG00000168610 ENSG00000089159 ENSG00000133216 ENSG00000106459 ENSG00000061938 ENSG00000160691 ENSG00000139921 ENSG00000144283 ENSG00000110395 ENSG00000120899 ENSG00000010810 ENSG00000188130 ENSG00000137575 ENSG00000137843 PMC7899164__F6 MitomiRNAs interactions with mitochondrial encoded genes either positive or negative suggestively PMC3579383__F1 Myelin-derived neurite growth inhibitors, their receptors, and intracellular signaling pathway ENSG00000169783 PMC6698799__F4 Proposed molecular mechanism of regulation of the pyrin inflammasome ENSG00000150782 ENSG00000163914 ENSG00000123143 ENSG00000065243 PMC4102778__F3 GSK-3 as potential target for therapeutic intervention in cancer ENSG00000177169 ENSG00000198793 ENSG00000169047 ENSG00000155792 ENSG00000164327 PMC11506062__F2 Major metabolic pathways at work within cancer cells ENSG00000135423 ENSG00000074800 ENSG00000198793 ENSG00000113161 ENSG00000169710 ENSG00000099194 ENSG00000078237 ENSG00000103257 PMC11506062__F1 Comparison of the major metabolic pathways in (A) normal and (B) cancer cells ENSG00000198793 ENSG00000103257 PMC4102778__F7 GSK-3 as potential target for therapeutic intervention in cancer ENSG00000106571 ENSG00000112210 ENSG00000171791 ENSG00000128602 PMC3880216__F5 Schematic diagram ENSG00000002330 PMC6826683__F10 Strategies for therapeutic intervention of cancer involving FADD ENSG00000134057 ENSG00000087586 ENSG00000168040 ENSG00000166851 PMC7830297__F1 TLR4 signaling pathway ENSG00000183735 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC6698799__F3 Proposed interaction model of Yersinia pestis effectors, Yops, with the pyrin inflammasome ENSG00000110921 ENSG00000163914 ENSG00000123143 ENSG00000065243 PMC4064057__F3 Genotype-specific steatogenic pathways associated with hepatitis C virus infection ENSG00000026103 PMC2726954__F2 Quest for genetic determinants of human longevity: challenges and insights ENSG00000118515 ENSG00000140443 PMC7028093__F2 Notch signaling pathway ENSG00000168214 ENSG00000283780 ENSG00000184384 ENSG00000148400 ENSG00000074181 ENSG00000196782 ENSG00000133961 ENSG00000184916 ENSG00000106003 PMC3860372__F1 Metabolic Homeostasis: HDACs Take Center Stage ENSG00000142178 ENSG00000160584 ENSG00000160741 PMC8095380__F7 Melatonin: Multi-Target Mechanism Against Diminished Ovarian Reserve Based on Network Pharmacology ENSG00000002330 ENSG00000111837 ENSG00000183691 ENSG00000213341 ENSG00000121879 ENSG00000069667 PMC6460806__F2 Interactive signaling pathway of EGFR-PI3K-mTOR ENSG00000006451 ENSG00000144118 ENSG00000163914 ENSG00000146648 PMC3981572__F9 Integrative model of the physiogenomic adaptations in adipose and liver tissue induced by energy overfeeding during the last 45 days of pregnancy ENSG00000120833 ENSG00000112964 ENSG00000105550 ENSG00000095321 ENSG00000103150 ENSG00000069667 ENSG00000167772 ENSG00000138823 ENSG00000161533 ENSG00000285482 ENSG00000196498 ENSG00000005469 ENSG00000062485 PMC9195137__F3 AMH Regulation by Steroids in the Mammalian Testis: Underlying Mechanisms and Clinical Implications ENSG00000291971 ENSG00000146648 PMC6068130__F1 Tryptophan (Trp) catabolic pathways PMC9123149__F2 Ectonucleotidases as bridge between the ATP and adenosine world: reflections on Geoffrey Burnstock ENSG00000196839 ENSG00000197594 PMC6923668__F1 Mechanism of mutant CALR-induced MPN and approaches for therapeutic targeting ENSG00000134982 ENSG00000117400 PMC5773610__F7 Mechanism of anti-allergic and inflammatory effect of quail egg on the food allergy induced EoE like disease alergic reaction ENSG00000164136 ENSG00000145777 PMC10886582__F3 Pathways related to activation of pyroptosis ENSG00000278718 ENSG00000162711 ENSG00000091592 PMC5640931__F1 Simplified scheme of liver architecture and Wnt/ Beta-catenin signalling ENSG00000134982 ENSG00000173599 ENSG00000168036 PMC5883082__F1 Programmed cell death protein 1 (PD-1) mediated intracellular signaling events during T cell activation PMC7000431__F1 Human and mouse bile acid synthesis and conjugation ENSG00000180432 ENSG00000135929 PMC5557697__F3 Model depicting the Cdc42-mediated regulation of EGF receptor interactions with c-Cbl ENSG00000110395 ENSG00000070831 ENSG00000138798 ENSG00000146648 PMC6492897__F2 Ingenuity pathways analysis (IPA) of ASS234 (5 μM) treatment ENSG00000166794 ENSG00000165280 ENSG00000132478 ENSG00000176153 ENSG00000023909 ENSG00000135624 ENSG00000101557 ENSG00000079999 ENSG00000128272 ENSG00000178573 ENSG00000177606 ENSG00000125656 ENSG00000156273 PMC10886582__F4 Necroptosis signaling pathway ENSG00000137275 ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC4128536__F4 STRING analysis of pathway enrichment and interaction in the altered mRNA in rat ARDS ENSG00000148346 ENSG00000147437 ENSG00000134982 ENSG00000163220 ENSG00000196154 ENSG00000131477 ENSG00000086232 ENSG00000172828 ENSG00000115850 ENSG00000160867 ENSG00000100412 ENSG00000167779 ENSG00000203618 ENSG00000087250 ENSG00000127324 ENSG00000105370 ENSG00000041357 PMC5067484__F1 Reelin signaling pathway in the developing cortex ENSG00000170558 ENSG00000198793 ENSG00000099942 ENSG00000173406 PMC4809675__F1 TNF biology, pathogenic mechanisms and emerging therapeutic strategies ENSG00000102871 ENSG00000168404 ENSG00000127191 PMC3251560__F7 Class IA PI3Kinase Regulatory Subunit, p85A, Mediates Mast Cell Development through Regulation of Growth and Survival Related Genes ENSG00000163947 ENSG00000148773 ENSG00000156858 ENSG00000135090 ENSG00000101346 ENSG00000285070 ENSG00000122779 ENSG00000168610 ENSG00000069667 ENSG00000149503 PMC11595909__F2 Signaling mechanism of IGF-1 upon binding to IGF-1 receptor (IGF-1R) ENSG00000002330 ENSG00000198793 ENSG00000140443 PMC11595909__F1 Effects of BDNF and NGF on the cell signaling processes that potentially lead to cellular effects with the end results of neuroregeneration or neurorepair PMC3251560__F9 Class IA PI3Kinase Regulatory Subunit, p85A, Mediates Mast Cell Development through Regulation of Growth and Survival Related Genes ENSG00000122180 ENSG00000104447 ENSG00000281024 ENSG00000068878 ENSG00000167525 PMC3251560__F8 Class IA PI3Kinase Regulatory Subunit, p85A, Mediates Mast Cell Development through Regulation of Growth and Survival Related Genes ENSG00000151276 ENSG00000144063 ENSG00000130706 ENSG00000131462 ENSG00000106688 ENSG00000277258 PMC4828918__F1 Figure demonstrates the wide array of interactions present in the Wnt signaling cascade ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000164690 ENSG00000126003 ENSG00000114315 ENSG00000128602 ENSG00000168646 ENSG00000146648 ENSG00000198300 PMC8718055__F6 Inhibition of the NLRP3/IL‐1B axis protects against sepsis‐induced cardiomyopathy ENSG00000162711 ENSG00000125538 ENSG00000115594 PMC11595909__F3 LIF signaling mechanism upon binding to LIF receptor that is constituted by LIFRB and gp130 heterodimer ENSG00000198793 ENSG00000128342 PMC4427718__F3 Biological network capturing the immune response and the metabolism of glycosaminoglycan and sphingolipid revealed from Ingenuity Pathway Analysis® (IPA®) ENSG00000139193 ENSG00000142192 ENSG00000156127 ENSG00000213614 ENSG00000107863 ENSG00000113520 ENSG00000184709 ENSG00000111670 ENSG00000189067 ENSG00000179163 ENSG00000291368 PMC6879915__F1 Apoptosis pathway ENSG00000006712 ENSG00000120868 ENSG00000168040 PMC7844024__F8 Differential NFKB pathway activation by 65–79*SE and 65–79*PE under M1 (A,B) or M2 (C,D) polarizing conditions ENSG00000104856 ENSG00000245848 ENSG00000100906 ENSG00000109320 ENSG00000115415 ENSG00000136997 ENSG00000173039 ENSG00000185591 ENSG00000162924 ENSG00000125347 ENSG00000168610 ENSG00000135605 PMC6582183__F2 Schematic portrays crosstalk between miR29 family and various signal transduction pathways involved in pathogenesis of Diabetic Nephropathy ENSG00000197635 ENSG00000168036 ENSG00000125084 ENSG00000079999 PMC5280013__F8 miR-146a plays a critical role in limiting the inflammatory response to ischemia-reperfusion ENSG00000136869 ENSG00000184216 PMC9570317__F1 Advances in Anti-Cancer Activities of Flavonoids in Scutellariae radix: Perspectives on Mechanism ENSG00000134057 ENSG00000135446 ENSG00000168036 ENSG00000123374 ENSG00000105810 ENSG00000118971 PMC2714185__F3 Major regulatory steps in the process of DNA damage response (DDR) ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000051180 ENSG00000140464 ENSG00000139618 PMC8975741__F8 The role of TSPAN6 in the regulation of signaling pathways in tumorigenesis ENSG00000000003 ENSG00000146648 PMC2714185__F1 Role of ATM in cellular responses ENSG00000149311 ENSG00000012048 ENSG00000144554 ENSG00000123374 PMC6667928__F3 Therapeutic strategies are involved in heme metabolic pathway ENSG00000177575 ENSG00000118777 PMC6667928__F2 Pivotal functions of the molecules in heme metabolic pathway in inflammation ENSG00000162711 ENSG00000136869 PMC4594483__F2 TGFB signaling ENSG00000163914 PMC7689298__F10 Proposed model of the involvement of TREM2 in the IL-4-induced anti-inflammatory response ENSG00000182578 ENSG00000140678 ENSG00000100280 ENSG00000173372 ENSG00000172243 ENSG00000172936 ENSG00000136869 ENSG00000118520 ENSG00000105639 PMC3427140__F4 Cross talk between focal adhesion kinase and cadherins: Role in regulating endothelial barrier function ENSG00000134982 ENSG00000168036 ENSG00000136826 PMC8204012__F1 New Insights Into the Role of Autophagy in Liver Surgery in the Setting of Metabolic Syndrome and Related Diseases ENSG00000162711 ENSG00000150782 ENSG00000125538 ENSG00000112561 PMC7999361__F2 Photoperiodic flowering in Arabidopsis, a long-day plant, and in rice, a short-day plant PMC8701046__F1 Homologous Recombination as a Fundamental Genome Surveillance Mechanism during DNA Replication ENSG00000173928 ENSG00000012048 ENSG00000083093 ENSG00000185379 ENSG00000182185 ENSG00000108384 ENSG00000051180 ENSG00000139618 PMC9411814__F6 Investigation of the mechanism of the anti-cancer effects of Astragalus propinquus Schischkin and Pinellia pedatisecta Schott (A&P) on melanoma via network pharmacology and experimental verification ENSG00000177455 ENSG00000103479 ENSG00000002330 ENSG00000179091 ENSG00000186716 ENSG00000169047 PMC4878678__F1 Genes in the MAP kinase signaling pathway (MAPK signaling pathway) identified using the KEGG-based pathway visualization tool ENSG00000170458 ENSG00000177606 ENSG00000130159 ENSG00000127191 ENSG00000146648 ENSG00000026103 PMC5711814__F2 Non-canonical regulation of HIF-1A stability ENSG00000198793 ENSG00000163914 PMC6511038__F3 Enrichment analysis of genes transcriptionally related to morphometric similarity ENSG00000164128 ENSG00000050628 ENSG00000123104 ENSG00000137841 ENSG00000112038 ENSG00000276825 ENSG00000169676 ENSG00000101188 ENSG00000148680 ENSG00000136160 ENSG00000170989 ENSG00000101327 ENSG00000186469 PMC5536018__F4 The alternative splicing and immune function of RLRs-mediated signaling pathways in response to viral infection in teleost fish ENSG00000088888 ENSG00000131323 ENSG00000276561 PMC5463089__F2 Ubiquitination mediates the NF‐KB activation and nuclear translocation ENSG00000145604 ENSG00000157764 ENSG00000116030 ENSG00000134160 ENSG00000151876 ENSG00000188612 PMC6314914__F3 Proposed PD-1 & PD-L1/L2 intra-cellular signaling between T cells and/or macrophage/monocytes, among others (e.g PMC8553822__F2 TLR signal transduction ENSG00000174123 ENSG00000174125 ENSG00000137275 ENSG00000150455 ENSG00000125347 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000172005 ENSG00000134070 ENSG00000136869 ENSG00000157625 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC8782664__F1 LPS versus Poly I:C model: comparison of long-term effects of bacterial and viral maternal immune activation on the offspring ENSG00000239732 ENSG00000088888 ENSG00000170458 ENSG00000130234 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC5587604__F5 Hydroquinone suppresses IFNB expression by targeting AKT/IRF3 pathway ENSG00000125538 ENSG00000172936 PMC4716143__F3 Evasion of the Immune Response by Trypanosoma cruzi during Acute Infection ENSG00000132693 ENSG00000062485 ENSG00000236625 PMC2779044__F4 Model describing the regulation of protein synthesis by AMPK, Ca++ and Akt -signaling pathways ENSG00000284161 ENSG00000167658 PMC5078051__F6 Loss of PAX8 in high-grade serous ovarian cancer reduces cell survival despite unique modes of action in the fallopian tube and ovarian surface epithelium ENSG00000178999 ENSG00000171791 ENSG00000166851 PMC8742179__F6 ZNF292 suppresses proliferation of ESCC cells through ZNF292/SKP2/P27 signaling axis ENSG00000145604 ENSG00000100387 ENSG00000113558 ENSG00000188994 PMC7073055__F1 Pathogenetic mechanisms in extranodal NK/T-cell lymphoma (ENKTL) ENSG00000291603 ENSG00000145839 ENSG00000213658 ENSG00000105656 ENSG00000027697 ENSG00000113263 ENSG00000171791 ENSG00000105639 PMC8994689__F3 Oxidative Stress and 4-hydroxy-2-nonenal (4-HNE): Implications in the Pathogenesis and Treatment of Aging-related Diseases ENSG00000197713 ENSG00000086991 ENSG00000167419 PMC8220134__F6 Early Growth Response Family Members 1–4 in Prognostic Value of Breast Cancer ENSG00000160888 ENSG00000172216 ENSG00000173917 ENSG00000122877 ENSG00000138386 ENSG00000104921 ENSG00000166886 ENSG00000131196 ENSG00000008056 ENSG00000130513 PMC8399174__F1 H2O2 Induces Major Phosphorylation Changes in Critical Regulators of Signal Transduction, Gene Expression, Metabolism and Developmental Networks in Aspergillus nidulans ENSG00000070831 ENSG00000102893 ENSG00000105402 PMC10522874__F2 Mature white adipocyte plasticity during mammary gland remodelling and cancer ENSG00000170365 ENSG00000137834 ENSG00000134982 ENSG00000168036 ENSG00000128602 PMC6470985__F3 Regulation of the mucus production by MAPK signalling ENSG00000163235 ENSG00000291971 ENSG00000130522 ENSG00000172936 ENSG00000185591 ENSG00000146648 ENSG00000145113 PMC5432547__F4 Action network of predicted targets of miRNAs overexpressed in GML mice stomachs ENSG00000122877 ENSG00000164938 PMC3911547__F12 Schematic diagram depicting the diverse outcomes of KSHV-induced 5LO and LTB4 in ECs and the consequences and roles of KSHV in viral pathogenesis ENSG00000142627 ENSG00000291971 PMC7457719__F6 Scheme illustration for Au4.5-induced NLRP3 inflammasome activation ENSG00000162711 ENSG00000125538 ENSG00000057663 PMC4269192__F1 Type 3 deiodinase expression on Warburg phenotype PMC10888202__F6 Comparative analysis of DEGs at different growth stages PMC11757137__F1 M5C modifications in immune signaling regulation ENSG00000174125 ENSG00000037474 ENSG00000276561 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000187554 ENSG00000130305 ENSG00000167468 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000183479 ENSG00000164342 PMC10941471__F7 Graphical abstract ENSG00000198670 PMC5190135__F1 Anticancer properties of nimbolide and pharmacokinetic considerations to accelerate its development ENSG00000138798 ENSG00000168036 ENSG00000167074 ENSG00000100985 ENSG00000168610 ENSG00000079999 PMC8195365__F8 Tentative mechanistic model for MERS-CoV-induced protective innate immune responses in alpaca respiratory tracts ENSG00000169245 ENSG00000162711 ENSG00000108691 ENSG00000187608 ENSG00000089127 ENSG00000115415 ENSG00000125538 ENSG00000157601 ENSG00000164136 ENSG00000276561 PMC10150574__F3 Signaling through the phosphatidylinositol 3-kinase (PI3K)/AKT pathway ENSG00000002330 ENSG00000070831 ENSG00000291971 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC6945844__F3 High Flux Through the Oxidative Pentose Phosphate Pathway Lowers Efficiency in Developing Camelina Seeds ENSG00000122966 ENSG00000172005 PMC7681028__F6 Functions and pathways of the type II MAGEs, MAGE-F1 and -L2 ENSG00000155229 ENSG00000182511 ENSG00000111237 ENSG00000288188 ENSG00000069329 PMC8841513__F5 CD39 in COVID-19 Severity: Dysregulation of Purinergic Signaling and Thromboinflammation ENSG00000162711 ENSG00000088888 PMC6627878__F2 Kinase signalling pathway ENSG00000198793 ENSG00000171791 ENSG00000105639 ENSG00000168685 PMC11202056__F8 STRING pathway analysis depicting protein–protein interaction (PPI) networks ENSG00000149451 ENSG00000159337 ENSG00000172680 ENSG00000177459 ENSG00000187821 ENSG00000172243 ENSG00000232258 ENSG00000141052 ENSG00000282937 ENSG00000169495 ENSG00000147138 ENSG00000187017 ENSG00000161929 ENSG00000154134 ENSG00000131400 ENSG00000143954 ENSG00000185149 PMC4412965__F3 Proteins involved in chromosomal fragility ENSG00000012061 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000178295 ENSG00000144554 ENSG00000165392 ENSG00000130997 ENSG00000197299 ENSG00000051180 PMC4469326__F4 JAK-STAT signalling pathway ENSG00000110395 ENSG00000137193 PMC2715808__F8 Regulation of mTORC1 signaling by mTOR S1261 phosphorylation ENSG00000198793 ENSG00000167965 PMC7218496__F9 Mechanism of AA on attenuating hypertrophic and fibrotic differentiation ENSG00000139219 ENSG00000125398 ENSG00000157766 ENSG00000108821 PMC4469326__F3 TNF signalling pathway ENSG00000167207 ENSG00000078747 ENSG00000102871 ENSG00000056558 ENSG00000007908 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000164305 ENSG00000026103 PMC4469326__F2 Toll-like receptor signalling pathway coverage ENSG00000239732 ENSG00000170458 ENSG00000172936 ENSG00000131323 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000164342 ENSG00000143387 PMC10742271__F4 Signaling pathway involved in the osteogenesis process due to Mg effect ENSG00000178860 ENSG00000092439 ENSG00000102158 ENSG00000168036 ENSG00000131196 PMC8294190__F5 Emerging Biological Functions of IL-17A: A New Target in Chronic Obstructive Pulmonary Disease? ENSG00000049768 ENSG00000168610 PMC8294190__F2 Emerging Biological Functions of IL-17A: A New Target in Chronic Obstructive Pulmonary Disease? ENSG00000138798 ENSG00000196591 ENSG00000146648 PMC8294190__F1 Emerging Biological Functions of IL-17A: A New Target in Chronic Obstructive Pulmonary Disease? ENSG00000056736 ENSG00000175104 ENSG00000163702 PMC8773363__F3 Atoh8 in Development and Disease ENSG00000170365 ENSG00000137834 ENSG00000168874 PMC9242402__F4 Metabolic Regulation of Hematopoietic Stem Cells ENSG00000125166 ENSG00000060982 ENSG00000115419 PMC9335447__F5 MicroRNA global profiling in cystic fibrosis cell lines reveals dysregulated pathways related with inflammation, cancer, growth, glucose and lipid metabolism, and fertility: an exploratory study ENSG00000065833 ENSG00000066926 ENSG00000291814 ENSG00000146648 PMC8580782__F0 Erythrocytosis: genes and pathways involved in disease development ENSG00000134086 ENSG00000005339 ENSG00000100985 PMC8539415__F1 Metabolic Perturbation and Synthetic Biology Strategies for Plant Terpenoid Production—An Updated Overview ENSG00000197429 ENSG00000150787 PMC6158481__F4 WNT/Beta-catenin signalling ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5384027__F1 Schematic of the DNA repair pathway ENSG00000149311 ENSG00000012048 ENSG00000163961 ENSG00000144554 ENSG00000080345 ENSG00000051180 ENSG00000112130 PMC7893585__F9 Free CA125 promotes ovarian cancer cell migration and tumor metastasis by binding Mesothelin to reduce DKK1 expression and activate the SGK3/FOXO3 pathway ENSG00000102854 PMC4800296__F1 Simplified representation of the PI3K-AKT-mTOR pathway in pancreatic neuroendocrine tumours ENSG00000106070 ENSG00000169047 ENSG00000198793 ENSG00000164327 PMC7894021__F6 Epidermal growth factor (EGF)‐mediated high‐mobility group protein A2 (HMGA2) transcription in hepatocellular carcinoma (HCC) cells ENSG00000138798 ENSG00000146648 PMC6533250__F7 Wnt/Beta-catenin interacts with the FGF pathway to promote proliferation and regenerative cell proliferation in the zebrafish lateral line neuromast ENSG00000070193 ENSG00000168036 PMC3969803__F3 Summary of the mechanism of several important drug candidates for anti-cancer metabolism therapies ENSG00000131473 ENSG00000169710 ENSG00000099194 ENSG00000175567 ENSG00000159399 PMC5845388__F5 Germinal center pathway in systemic lupus erythematosus ENSG00000173599 ENSG00000145321 PMC3969803__F2 Summary of key changes in cancer metabolic reprogramming ENSG00000131473 ENSG00000065833 ENSG00000169710 ENSG00000099194 ENSG00000175567 ENSG00000159399 PMC3167094__F1 New Hormonal Therapies for Castration Resistant Prostate Cancer ENSG00000086696 ENSG00000151632 ENSG00000196620 ENSG00000187134 PMC6487735__F1 Schematic representation of the linkage between SAMe, SAH, sarcosine metabolic pathway and methionine cycle ENSG00000179761 PMC5009710__F6 Simplified model for extracellular phytohormones that regulate enzyme-encoding genes or TFs in phytohormone biosynthesis by signal transduction pathways ENSG00000105722 ENSG00000136997 PMC3864579__F1 CD4 T-cell immunotherapy for chronic viral infections and cancer ENSG00000134982 ENSG00000186716 ENSG00000173599 ENSG00000113520 PMC9170610__F3 Calcineurin in development and disease ENSG00000259207 ENSG00000070831 ENSG00000137672 PMC9101307__F3 New Player in Depression: MiRNAs as Modulators of Altered Synaptic Plasticity ENSG00000138795 ENSG00000168036 ENSG00000111186 ENSG00000096717 PMC8807567__F3 Understanding the Emerging Link Between Circadian Rhythm, Nrf2 Pathway, and Breast Cancer to Overcome Drug Resistance ENSG00000109670 PMC8807567__F2 Understanding the Emerging Link Between Circadian Rhythm, Nrf2 Pathway, and Breast Cancer to Overcome Drug Resistance ENSG00000100387 ENSG00000125538 ENSG00000176153 ENSG00000079999 PMC8807567__F1 Understanding the Emerging Link Between Circadian Rhythm, Nrf2 Pathway, and Breast Cancer to Overcome Drug Resistance ENSG00000105516 PMC4624764__F8 Lentivirus Live Cell Array for Quantitative Assessment of Gene and Pathway Activation during Myogenic Differentiation of Mesenchymal Stem Cells ENSG00000170365 ENSG00000186260 ENSG00000141448 ENSG00000196588 ENSG00000086991 ENSG00000185591 ENSG00000141052 ENSG00000164093 ENSG00000136826 PMC8589187__F1 Arginase Signalling as a Key Player in Chronic Wound Pathophysiology and Healing ENSG00000123505 ENSG00000128602 ENSG00000116649 PMC8348955__F11 Fibroblast Growth Factor 21 Response in a Preclinical Alcohol Model of Acute-on-Chronic Liver Injury ENSG00000160867 ENSG00000105550 ENSG00000167910 ENSG00000198793 ENSG00000077782 PMC4615225__F6 Overview of regulatory networks in which miRNA/target pairs function during the rice response to fungal elicitors ENSG00000105722 ENSG00000092847 ENSG00000134698 PMC3672663__F1 The canonical Hedgehog signalling pathway in mammals ENSG00000180447 ENSG00000164161 ENSG00000144857 ENSG00000128602 PMC9620658__F1 Targets of aspirin in bladder cancer: bioinformatics analysis ENSG00000100906 ENSG00000132646 ENSG00000136997 ENSG00000151617 ENSG00000073756 ENSG00000164305 PMC4406394__F2 JAK2 Inhibitors: What’s the true therapeutic potential? ENSG00000198793 PMC6088189__F1 Tetraspanin roles during HIV-1 infection ENSG00000156298 ENSG00000110651 ENSG00000010278 ENSG00000135404 ENSG00000137845 ENSG00000121966 PMC9045983__F6 Histone Methyltransferase SETDB1 Promotes Immune Evasion in Colorectal Cancer via FOSB-Mediated Downregulation of MicroRNA-22 through BATF3/PD-L1 Pathway ENSG00000123685 ENSG00000125740 ENSG00000143379 PMC7025498__F11 Celastrol-suppressed VM and angiogenesis in glioma ENSG00000142627 ENSG00000198793 ENSG00000112715 PMC2850885__F7 Proposed model of a EGFR/Beta-catenin/cyclin D1 signaling pathway in oral cancer ENSG00000134982 ENSG00000138798 ENSG00000168036 ENSG00000146648 PMC4926181__F2 HTLV-1 Infection and Adult T-Cell Leukemia/Lymphoma—A Tale of Two Proteins: Tax and HBZ ENSG00000112130 PMC8877852__F1 Characterization and Interaction Analysis of the Secondary Cell Wall Synthesis-Related Transcription Factor PmMYB7 in Pinus massoniana Lamb. ENSG00000145020 ENSG00000084774 PMC8675329__F3 Novel Insight Into the Fate of Cardiomyocytes in Ischemia-Reperfusion Injury: From Iron Metabolism to Ferroptosis ENSG00000168003 ENSG00000128272 ENSG00000151012 ENSG00000144895 ENSG00000168374 ENSG00000079999 ENSG00000128965 PMC11278107__F3 Antifibrotic activity of EchA in SSc model ENSG00000177575 ENSG00000275385 ENSG00000129226 ENSG00000007171 PMC2785475__F4 Expression-Based Network Biology Identifies Alteration in Key Regulatory Pathways of Type 2 Diabetes and Associated Risk/Complications ENSG00000004975 ENSG00000002330 ENSG00000291971 ENSG00000010810 ENSG00000186716 ENSG00000169047 ENSG00000164399 ENSG00000113520 ENSG00000105639 ENSG00000146648 ENSG00000196396 PMC8630233__F6 Intestinal microbiota and their metabolic contribution to type 2 diabetes and obesity ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC2774576__F1 Diagram illustrating the biosynthetic pathway of n-3 and n-6 fatty acids from dietary precursors ENSG00000134824 ENSG00000149485 PMC6345611__F1 B-cell receptor (BCR) signaling pathways important to the pathophysiology and treatment options for chronic lymphocytic leukemia (CLL) ENSG00000095585 ENSG00000186716 ENSG00000010671 PMC8724284__F4 Wnt/Beta-catenin signalling: function, biological mechanisms, and therapeutic opportunities ENSG00000169071 ENSG00000134982 ENSG00000185483 ENSG00000168036 ENSG00000154310 ENSG00000132693 PMC11625809__F3 LncRNAs are involved in the AR pathway to regulate enzalutamide resistance ENSG00000124422 ENSG00000165119 PMC11625809__F2 LncRNAs are involved in the neuroendocrine secretion of prostate cancer ENSG00000173894 ENSG00000168036 ENSG00000168610 PMC11625809__F1 Neuroendocrine Evolution and drug resistance mechanism of prostate cancer PMC7472859__F8 The key proteins related to the PPI-PD network obtained as common proteins with the highest score through five ranking methods ENSG00000142192 ENSG00000070831 ENSG00000109320 ENSG00000112715 ENSG00000137845 ENSG00000121879 ENSG00000164305 ENSG00000163631 ENSG00000150991 ENSG00000169429 ENSG00000136869 ENSG00000100985 ENSG00000026103 PMC10962462__F2 Novel molecular targets in endometrial cancer (EC) ENSG00000149311 ENSG00000175054 ENSG00000164430 ENSG00000198793 ENSG00000277273 ENSG00000146648 ENSG00000134480 ENSG00000276876 PMC4279155__F1 The heme biosynthetic pathway and aspects of its regulation in hepatocytes ENSG00000066926 ENSG00000126088 ENSG00000157601 ENSG00000256269 PMC5830900__F1 Role of the TGFB family in mammary gland development and maturation ENSG00000019991 ENSG00000120149 PMC3161159__F1 Retinoid metabolic pathway ENSG00000095596 ENSG00000187553 ENSG00000184254 ENSG00000121207 ENSG00000003137 PMC7920342__F8 Schematic drawing of the role of Lhx6 in regulating root furcation development ENSG00000106852 ENSG00000152591 ENSG00000168646 PMC7776261__F6 Proposed model to illustrate the regulation of quiescence stage of persisting chronic myeloid leukemia (CML) leukemic stem cells by their microenvironment ENSG00000168610 PMC9605185__F3 Towards Precision Oncology: The Role of Smoothened and Its Variants in Cancer ENSG00000173040 ENSG00000128602 PMC6287140__F4 Putative inhibitory pathway of Ac-ME in mediating the inflammatory response ENSG00000291971 ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC2921612__F1 Molecular Diagnosis and Therapy of Kidney Cancer ENSG00000134086 ENSG00000163235 ENSG00000198793 ENSG00000146648 PMC11954244__F2 Isoflavone biosynthetic pathway ENSG00000108849 ENSG00000197429 ENSG00000150787 PMC8106074__F1 Hepcidin pathway and the regulation of body iron homeostasis ENSG00000010704 ENSG00000106327 ENSG00000187045 ENSG00000105697 ENSG00000168610 PMC3465249__F3 Changes in hepatic gene expression in the KEGG PPAR signalling pathway in SNEB compared to MNEB cows ENSG00000150991 ENSG00000100979 PMC4467136__F5 Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1 ENSG00000273529 ENSG00000133961 ENSG00000114315 ENSG00000135144 PMC7965852__F2 LncRNA-mediated lineage transition ENSG00000019991 ENSG00000084093 ENSG00000107562 ENSG00000163235 ENSG00000113070 ENSG00000138798 ENSG00000170558 ENSG00000197632 ENSG00000171791 ENSG00000253352 ENSG00000140443 PMC4640886__F1 Etomidate on the Steroidogenesis of Rat Immature Leydig Cells ENSG00000073060 ENSG00000138039 ENSG00000203857 PMC7404231__F2 Stress-response mechanisms ENSG00000128272 ENSG00000144895 PMC4619386__F6 DDVP profoundly affects energy metabolism ENSG00000125166 ENSG00000143252 ENSG00000073578 ENSG00000111713 ENSG00000102893 ENSG00000172340 ENSG00000076555 ENSG00000105723 ENSG00000026103 PMC7197780__F1 Effect of ovarian stimulation on the expression of piRNA pathway proteins ENSG00000095627 ENSG00000143194 ENSG00000146453 PMC3157546__F7 The role of TAK1 signaling in bone metastasis ENSG00000100985 PMC7531533__F1 Schematic showing how retinoids regulate thermogenic gene expression in adipocytes PMC6985464__F3 Molecular signaling in poultry feather follicle and feather development ENSG00000134982 ENSG00000168036 ENSG00000128602 PMC5209283__F7 Stat3 and C/EBPB synergize to induce miR-21 and miR-181b expression during sepsis ENSG00000135446 ENSG00000168610 PMC8747952__F1 An updated overview of recent advances, challenges, and clinical considerations of IL-6 signaling blockade in severe coronavirus disease 2019 (COVID-19) ENSG00000168610 PMC3575850__F8 Hypothetical model for functional redundancy of Rad18 and NHEJ in responding to oxidative DNA damage during G1 ENSG00000132646 ENSG00000070950 ENSG00000130997 ENSG00000138385 PMC7977448__F2 Inflammasome activation ENSG00000162711 ENSG00000163568 ENSG00000125538 ENSG00000163914 ENSG00000091592 ENSG00000091106 ENSG00000276068 PMC5419167__F7 Genomic and nongenomic cross talk of the GnRHR and GR signaling pathways on the GnRHR promoter in LBT2 cells ENSG00000109163 ENSG00000177606 ENSG00000155974 PMC1782438__F2 Role of adaptors in T-cell signalling ENSG00000213658 ENSG00000070831 ENSG00000010810 ENSG00000113263 PMC7738984__F8 Identification of the target genes and construction of its dynamic regulatory network ENSG00000288411 ENSG00000138798 ENSG00000167083 ENSG00000115353 ENSG00000127588 ENSG00000146648 ENSG00000102468 PMC10030840__F2 Genetic analyses of DNA repair pathway associated genes implicate new candidate cancer predisposing genes in ancestrally defined ovarian cancer cases ENSG00000134899 ENSG00000038002 ENSG00000158169 PMC7298284__F1 Cyclin B1‐MAD1 interaction promotes checkpoint signaling at kinetochores ENSG00000137812 ENSG00000047410 ENSG00000134057 ENSG00000171444 ENSG00000134982 ENSG00000143228 PMC7690154__F1 MiRNA biogenesis and regulatory signaling pathways ENSG00000205250 ENSG00000128191 ENSG00000113360 ENSG00000132341 PMC9669513__F2 Effect of oncogenic activation of RAS signaling in OC ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC7935792__F2 Antigen presentation process PMC7823159__F7 Drosophila Activin signaling promotes muscle growth through InR/TORC1-dependent and -independent processes ENSG00000164327 PMC6593070__F7 Curcumin mediated inhibition of cell growth via inhibition of AKT signaling and activation of mitochondrial apoptotic pathway ENSG00000113600 ENSG00000006712 ENSG00000150907 ENSG00000171791 PMC6031772__F1 Arsenic Trioxide and Thalidomide on Angiogenesis and VEGF in Leukemia ENSG00000198793 PMC8824753__F2 Oral-Intestinal Microbiota in Colorectal Cancer: Inflammation and Immunosuppression ENSG00000162711 ENSG00000181847 ENSG00000163220 ENSG00000163568 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000110218 PMC6317254__F2 Graphene oxide down-regulates genes of the oxidative phosphorylation complexes in a glioblastoma ENSG00000143252 ENSG00000147684 ENSG00000073578 ENSG00000065518 ENSG00000130414 ENSG00000117118 ENSG00000110717 ENSG00000099795 ENSG00000175567 PMC11609686__F1 Illustration shows the suggested role of SARS-CoV-2 in EMT induced by ROS in cancer cells ENSG00000167601 ENSG00000162711 ENSG00000130234 ENSG00000198793 PMC12104694__F1 Indole‐3‐acetic acid (IAA)‐mediated signaling pathways in epithelial and endothelial cells ENSG00000085982 ENSG00000168036 ENSG00000172936 ENSG00000136869 ENSG00000135605 ENSG00000293532 ENSG00000106546 ENSG00000133216 PMC10100231__F7 Hypertrophic and fibrotic human PKD hearts are associated with macrophage infiltration and abnormal TGFB1 signaling ENSG00000105329 ENSG00000168036 PMC7605689__F2 netboxr: Automated discovery of biological process modules by network analysis in R ENSG00000171855 ENSG00000111581 ENSG00000188379 ENSG00000157404 ENSG00000135439 ENSG00000164975 ENSG00000147133 ENSG00000149294 ENSG00000118971 ENSG00000121879 ENSG00000142166 ENSG00000179295 ENSG00000107186 ENSG00000177047 ENSG00000182004 ENSG00000185482 ENSG00000128052 ENSG00000277263 ENSG00000146731 ENSG00000139687 ENSG00000136158 ENSG00000118972 ENSG00000133056 ENSG00000137193 ENSG00000107295 ENSG00000111537 ENSG00000110395 ENSG00000135446 ENSG00000175899 ENSG00000135407 ENSG00000146648 ENSG00000198625 PMC4146704__F6 MIF-CD74-Lyn signaling cascade during osteoclastogenesis ENSG00000019582 ENSG00000033327 ENSG00000026508 ENSG00000131196 PMC7662069__F8 MiR-497-5p regulating osteo/odontogenic differentiation of SCAP PMC7147366__F3 Key metabolic pathways (glutathione metabolic pathway) involved in the interaction between GNPs and HDFs and the key metabolites involved ENSG00000002549 PMC3426490__F2 Flow chart showing the genes involved in TLR signaling pathway ENSG00000170458 ENSG00000168040 ENSG00000150455 ENSG00000164342 PMC8915851__F1 Of NRF2 Pathway in Preventing Developmental and Reproductive Toxicity of Fine Particles ENSG00000181019 ENSG00000178573 ENSG00000079999 PMC6723309__F1 Adenovirus-directed innate immunity through nuclear factor kappa-light-chain-enhancer of activated B cells (NFKB) ENSG00000163464 ENSG00000164430 ENSG00000136869 ENSG00000146648 PMC8200290__F4 Up-regulated genes in advanced basal cell carcinoma overlaid on the KEGG “extracellular matrix–receptor interactions” pathway ENSG00000136457 ENSG00000135218 ENSG00000110799 ENSG00000026508 PMC9485571__F1 Uncovering incontinentia pigmenti: From DNA sequence to pathophysiology ENSG00000115008 ENSG00000125538 ENSG00000269335 ENSG00000173039 PMC8200290__F1 Up-regulated genes in basal cell carcinoma compared with normal skin, overlaid on the KEGG “Pathways in Cancer” pathway ENSG00000134982 ENSG00000133116 ENSG00000172005 ENSG00000099942 PMC5436295__F3 MAPK signaling pathway ENSG00000087095 ENSG00000172680 ENSG00000148798 ENSG00000138798 ENSG00000130159 ENSG00000175104 ENSG00000127191 ENSG00000146648 ENSG00000081189 ENSG00000196712 ENSG00000026103 PMC4364530__F1 MITOCHONDRIAL DISEASES PART I: MOUSE MODELS OF OXPHOS DEFICIENCIES CAUSED BY DEFECTS ON RESPIRATORY COMPLEX SUBUNITS OR ASSEMBLY FACTORS ENSG00000006695 ENSG00000169021 ENSG00000128609 ENSG00000088682 ENSG00000138495 ENSG00000284194 PMC5985952__F7 Sequential activation of polyadenylation during oocyte maturation in Xenopus ENSG00000172680 ENSG00000096088 ENSG00000276876 PMC8040310__F8 The proposed molecular mechanism highlighting the role of betulinic acid in the pathophysiology of SCI and subsequent neurological recovery ENSG00000162711 ENSG00000150782 ENSG00000125538 ENSG00000198793 ENSG00000112561 PMC8965895__F2 Treatment of Androgenetic Alopecia Using PRP to Target Dysregulated Mechanisms and Pathways ENSG00000281324 ENSG00000168036 PMC7734336__F7 Elements of the SPINK1 pathway are involved in PDAC progression ENSG00000154646 PMC6723309__F2 Hypothetical model for adenoviral regulation of stress-induced EGFR signaling through NFKB ENSG00000127445 ENSG00000074319 ENSG00000274145 ENSG00000146648 PMC8440965__F5 Acute Impacts of Different Types of Exercise on Circulating Alpha-Klotho Protein Levels ENSG00000198793 ENSG00000140443 PMC6436826__F1 Molecular Mechanisms of Regulation of Sphingosine Kinase 1 ENSG00000100422 PMC3650130__F85 Recently, Zhang et al ENSG00000149311 PMC5515628__F1 AD immunopathology and mechanisms of action of targeted therapies ENSG00000145623 ENSG00000204671 ENSG00000113520 PMC6721560__F4 The PI3K/Akt/mTOR signaling pathway ENSG00000149212 ENSG00000198793 ENSG00000163914 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC3606104__F3 Identification of genetic networks that regulate the induction of filamentous growth ENSG00000196511 ENSG00000175854 ENSG00000135336 ENSG00000004897 ENSG00000073111 ENSG00000197601 ENSG00000117399 PMC7909315__F4 F-actin correlation pathway diagram ENSG00000163914 ENSG00000067900 ENSG00000140403 PMC4382258__F2 Essential role for autophagy in life span extension ENSG00000177169 ENSG00000112561 PMC8093429__F1 Cellular Responses to the Efferocytosis of Apoptotic Cells ENSG00000057663 ENSG00000124839 PMC8200538__F3 Comparative Transcriptomics of IBD Patients Indicates Induction of Type 2 Immunity Irrespective of the Disease Ideotype ENSG00000102962 ENSG00000081181 ENSG00000107562 ENSG00000197635 ENSG00000137033 ENSG00000287542 ENSG00000043462 ENSG00000099203 ENSG00000115602 ENSG00000178573 ENSG00000102970 ENSG00000107485 ENSG00000155508 ENSG00000113263 ENSG00000124181 ENSG00000073861 PMC3542205__F5 Illustration of the expression levels of enzymes within the glycolytic pathway and major connections in the C ENSG00000169299 ENSG00000013375 PMC5499884__F10 Molecular indices of viral disease development in wild migrating salmon ENSG00000213928 ENSG00000105329 ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000157601 ENSG00000197272 ENSG00000169032 ENSG00000112715 ENSG00000230034 ENSG00000180210 ENSG00000132530 ENSG00000239732 ENSG00000088888 ENSG00000011422 ENSG00000113520 ENSG00000136869 ENSG00000164342 ENSG00000129226 ENSG00000115267 ENSG00000125347 ENSG00000276561 ENSG00000101695 ENSG00000184979 ENSG00000108691 ENSG00000111537 ENSG00000138642 ENSG00000112115 ENSG00000146648 PMC11278853__F2 Emerging evidence regarding the anti-cancer features of novel lipid-lowering treatments, including CETP inhibitors, bempedoic acid, and PCSK9 inhibitors ENSG00000131473 ENSG00000168646 ENSG00000169174 PMC11278853__F1 Schematic illustration depicting the potential anti-inflammatory effects of hypolipidemic agents primarily targeting LDL-C reduction ENSG00000131473 ENSG00000162711 ENSG00000113161 ENSG00000112715 ENSG00000162692 ENSG00000169174 PMC10472888__F3 GPX4 in cell death, autophagy, and disease ENSG00000151012 ENSG00000167468 PMC8201009__F1 Cancer-Associated Glycosphingolipids as Tumor Markers and Targets for Cancer Immunotherapy ENSG00000069482 PMC5415836__F2 Following TLR2-ligand interaction a signaling pathway is started using MYD88 as an adaptor molecule ENSG00000134070 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC5703693__F3 Molecular mechanisms of the attenuation of PI3K and Akt, and the dysregulation of PI3K/Akt signaling pathway by gingipains ENSG00000135899 ENSG00000002330 ENSG00000198793 PMC11683146__F6 Tyr-Pro-induced Aß signaling pathway in SAMP8 mice ENSG00000142192 ENSG00000119912 PMC8262334__F2 Gastric Cancer Stem Cells: A Glimpse on Metabolic Reprogramming ENSG00000008710 ENSG00000074800 ENSG00000101115 PMC8945445__F2 Links between Insulin Resistance and Periodontal Bacteria: Insights on Molecular Players and Therapeutic Potential of Polyphenols ENSG00000150782 ENSG00000169047 ENSG00000172936 ENSG00000175104 PMC7915224__F5 RAS regulation by posttranslational modifications ENSG00000291971 ENSG00000168036 PMC3124472__F4 Proteomic Analysis of Pathways Involved in Estrogen-Induced Growth and Apoptosis of Breast Cancer Cells ENSG00000076864 ENSG00000002330 ENSG00000105397 ENSG00000291971 ENSG00000020633 ENSG00000168036 ENSG00000143933 ENSG00000155760 PMC4659505__F12 Complexity of the direct and indirect effects of mTOR on signaling pathways ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC11557563__F2 Glycolysis and its ancillary pathways in WB muscle ENSG00000092621 PMC4581244__F1 Alterations of the KP in EAE and MS ENSG00000111537 PMC2603471__F1 Ageing, oxidative stress and cancer: paradigms in parallax ENSG00000148346 ENSG00000041982 ENSG00000069482 ENSG00000105329 ENSG00000058085 ENSG00000109321 ENSG00000171791 ENSG00000100985 ENSG00000148344 ENSG00000198300 ENSG00000115461 ENSG00000121966 PMC2495063__F3 Germline Mutations and Variants in the Succinate Dehydrogenase Genes in Cowden and Cowden-like Syndromes ENSG00000198793 PMC5124559__F7 Schematic representation of the peptide generation pathway ENSG00000012048 ENSG00000135100 ENSG00000120054 ENSG00000168036 ENSG00000107611 PMC7216262__F3 mTOR Signaling at the Crossroad between Metazoan Regeneration and Human Diseases ENSG00000242689 ENSG00000138798 ENSG00000198793 PMC3807004__F2 Mitochondrial biogenesis by HLA20 involves activation of the Peroxisome Proliferator-Activated Receptor Gamma Co-Activator 1 Alpha (PGC-1A) pathway ENSG00000164087 PMC4716629__F1 NFKB/p65 ubiquitination and degradation signaling ENSG00000173163 ENSG00000111653 ENSG00000120913 PMC4727420__F2 Global view of biological processes and molecular functions of HDL proteins ENSG00000130208 ENSG00000189058 ENSG00000110244 ENSG00000134982 ENSG00000278032 ENSG00000273686 ENSG00000236625 ENSG00000112293 ENSG00000138207 ENSG00000288411 ENSG00000005421 ENSG00000145192 ENSG00000188404 ENSG00000100979 ENSG00000158874 ENSG00000163501 ENSG00000267467 ENSG00000148965 PMC3970295__F4 Wnt signaling as a pathway to increase bone formation ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000165879 ENSG00000168036 PMC3527976__F2 Two rapamycin-sensitive myogenic mTOR signaling pathways ENSG00000169047 ENSG00000198793 PMC6970510__F2 Different regulation of PAQR3 on multiple signaling pathways.Notes: Reproduced from Zhao Z, Chen Y ENSG00000166167 ENSG00000134574 ENSG00000126775 ENSG00000122691 ENSG00000163291 PMC8222785__F1 Key Pathway to Cancer Resilience: The Role of Autophagy in Glioblastomas ENSG00000198793 ENSG00000170430 ENSG00000100941 ENSG00000146648 PMC2888472__F2 Simplified scheme of signaling pathways required for maintenance of pluripotency of mESC (top panel) and hESC (bottom panel) ENSG00000170365 ENSG00000128342 ENSG00000168610 PMC7406421__F2 Mechanism of human CoVID-19 infection: 1: infected animals can infect Humans followed by human-to-human transmission through aerial droplets and contact ENSG00000108691 ENSG00000137033 ENSG00000130234 ENSG00000132693 PMC4981676__F1 Overall organization of JNK signaling pathways ENSG00000070831 PMC9092395__AF1 LncRNA CBR3-AS1 promotes osteosarcoma progression through the network of miR-140-5p/DDX54-NUCKS1-mTOR signaling pathway ENSG00000123064 ENSG00000198793 PMC8529555__F6 Network-based approach reveals the dysregulated transcriptional regulation in non-alcoholic fatty liver disease ENSG00000213996 ENSG00000110921 ENSG00000149084 ENSG00000172893 ENSG00000167910 ENSG00000113161 ENSG00000169710 ENSG00000120437 ENSG00000167508 ENSG00000065833 ENSG00000171720 ENSG00000130164 ENSG00000170522 ENSG00000116133 ENSG00000109929 ENSG00000104549 ENSG00000131473 ENSG00000100811 ENSG00000262785 ENSG00000100344 ENSG00000099194 ENSG00000052802 ENSG00000160752 ENSG00000067064 ENSG00000128272 ENSG00000001630 ENSG00000134824 ENSG00000149809 ENSG00000149485 ENSG00000015520 ENSG00000066136 ENSG00000136872 ENSG00000198911 PMC5711019__F9 Hyperthyroidism, but not hypertension, impairs PITX2 expression leading to Wnt-microRNA-ion channel remodeling ENSG00000138792 ENSG00000148798 ENSG00000174306 ENSG00000164093 ENSG00000143603 PMC3515033__F5 Cytokine intracellular signaling pathways ENSG00000111537 ENSG00000115415 ENSG00000102871 ENSG00000125538 ENSG00000172936 ENSG00000168040 ENSG00000127191 ENSG00000115594 PMC3515033__F4 Neural and humoral activation of the brain by the periphery PMC3515033__F3 Classification of nucleotide-binding oligomerization domain proteins (Nods) ENSG00000167207 ENSG00000125538 ENSG00000106100 PMC4648866__F1 Glycerol biosynthesis in respond to osmotic stress and redox statue and the interrelationship with yeast-derived aroma compounds in S PMC3515033__F2 Classification of Toll-like receptors (TLRs) ENSG00000174125 ENSG00000239732 ENSG00000111537 ENSG00000187554 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC12004807__F6 Distribution of genes in the TNF signaling pathway ENSG00000169245 ENSG00000078747 ENSG00000164136 ENSG00000166278 ENSG00000128342 ENSG00000083799 ENSG00000168040 ENSG00000168404 PMC10814963__F4 Proposed model for Fyn-CD133 signaling to the PI3K pathway induces melanoma intrinsic and acquired resistance to anti-cancer agent in melanoma cells ENSG00000157764 ENSG00000010810 PMC10814963__F2 Common mechanisms of melanoma progression and treatment resistance ENSG00000157764 ENSG00000146648 PMC11519383__F7 Schematic summary of the study ENSG00000159216 ENSG00000105329 ENSG00000137801 PMC8870128__F2 Antiplatelet Agents Affecting GPCR Signaling Implicated in Tumor Metastasis ENSG00000120436 PMC3432767__F1 Rac and RhoA signaling pathways during cytokinesis ENSG00000102606 ENSG00000114346 ENSG00000149269 ENSG00000134215 ENSG00000163914 PMC8638120__F3 Functional enrichment of alternative splicing events with NEASE reveals insights into tissue identity and diseases ENSG00000175416 ENSG00000185344 ENSG00000197959 ENSG00000168818 ENSG00000183020 ENSG00000122705 ENSG00000111450 ENSG00000105402 ENSG00000136888 ENSG00000141367 PMC5852601__F1 Relationship between epithelial-to-mesenchymal transition (EMT) and the Wnt pathway in glioblastoma-derived stem cells (GSCs) ENSG00000281324 ENSG00000163251 ENSG00000162337 ENSG00000134982 ENSG00000185483 PMC11731108__F2 T cell senescence‐related signaling pathways ENSG00000149311 ENSG00000291603 ENSG00000164430 ENSG00000115415 ENSG00000164362 ENSG00000168610 PMC8150330__F1 Cnicin as an Anti-SARS-CoV-2: An Integrated In Silico and In Vitro Approach for the Rapid Identification of Potential COVID-19 Therapeutics ENSG00000115977 ENSG00000140564 ENSG00000130234 ENSG00000184012 PMC3894710__F2 Autophagy: A Crucial Moderator of Redox Balance, Inflammation, and Apoptosis in Lung Disease ENSG00000177169 ENSG00000126775 ENSG00000198793 PMC7794713__F2 Net cholesterol flow through the body ENSG00000130164 ENSG00000113161 ENSG00000120437 ENSG00000023839 PMC1768457__F1 CD14/toll-like receptor 4 (TLR4) intracellular signalling complex ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC7982659__F3 Ingenuity Pathway Analysis (IPA) ENSG00000245848 ENSG00000105329 ENSG00000109321 ENSG00000124882 ENSG00000113070 ENSG00000108342 ENSG00000184371 ENSG00000092067 ENSG00000169032 ENSG00000122779 ENSG00000137764 PMC9297058__F1 Brain Abnormalities in PIK3CA-Related Overgrowth Spectrum: Physician, Patient, and Caregiver Experiences ENSG00000070831 ENSG00000198793 PMC1636619__F8 Oncogene cooperation in malignant rasV12, scrib−/− tumors PMC12240100__F6 Hippo-YAP signaling pathwayOverview of the Hippo-YAP signaling pathway, including the interactions between MST1/2, LATS1/2, YAP/TAZ, and TEAD ENSG00000114978 ENSG00000150457 ENSG00000131023 PMC12240100__F5 PI3K/Akt signaling pathwayThe PI3K/Akt signaling pathway regulates cell growth, survival, metabolism, and angiogenesis ENSG00000146648 PMC12240100__F3 Hedgehog (Hh) signaling pathwayThe Hedgehog (Hh) signaling pathway regulates embryogenesis, cell proliferation, and tissue repair ENSG00000106571 ENSG00000166813 ENSG00000164690 ENSG00000128602 ENSG00000105204 PMC12240100__F2 Canonical Wnt/Beta-catenin signaling pathwayCanonical Wnt/Beta-catenin signaling pathway: the Wnt/Beta-catenin pathway regulates cell proliferation, differentiation, and survival ENSG00000071564 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000138798 ENSG00000026508 ENSG00000168036 PMC4287430__F1 Predicted model of the S ENSG00000197713 ENSG00000213658 ENSG00000198670 ENSG00000080166 ENSG00000105953 ENSG00000100504 ENSG00000062485 ENSG00000254550 PMC8247027__F1 Pathogenic postzygotic mosaicism in the tyrosine receptor kinase pathway: potential unidentified human disease hidden away in a few cells ENSG00000198793 PMC5998742__F1 Toll-like receptor (TLR) 4 signaling pathway ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC3815682__F1 Comparison of typical mammalian cell citrate metabolism and the metabolic pathway for net citrate production ENSG00000122966 ENSG00000172005 ENSG00000062485 PMC11932283__F6 Cerebral CYP enzymes in major exogenous substance metabolism—opioid biotransformation ENSG00000138115 PMC8438590__F1 Antibody dependent enhancement: Unavoidable problems in vaccine development ENSG00000183735 ENSG00000213928 ENSG00000172936 ENSG00000131323 ENSG00000145782 ENSG00000168610 ENSG00000276561 ENSG00000057663 ENSG00000164342 PMC11829548__F2 Toll-like receptor signaling pathways ENSG00000239732 ENSG00000187554 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC7286274__F3 Putative signaling effect of ⋅NO on nodule development ENSG00000108798 PMC6209660__F6 Potential mechanism of sodium butyrate on STZ-induced type 1 diabetes ENSG00000125538 ENSG00000189403 PMC11961548__F7 Construction of miRNA-gene regulatory networks in rat fatty liver associated PNF cases ENSG00000141867 ENSG00000100129 ENSG00000130699 ENSG00000197780 PMC12220693__F1 Normal tryptophan synthesis pathway ENSG00000183077 PMC9548536__F3 Biomarker-driven feedback control of synthetic biology systems for next-generation personalized medicine ENSG00000113520 ENSG00000243646 ENSG00000168610 PMC3246665__F6 Diagram of signalling pathways indicating the possible mechanism by which sildenafil reverses the memory deficits in aged transgenic Tg2576 mice ENSG00000198576 PMC11672511__F5 TNFR1-mediated survival and cell death pathways ENSG00000124256 ENSG00000183735 ENSG00000123240 ENSG00000137275 ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000285379 ENSG00000026103 PMC11672511__F4 NLRP3 inflammasome induction by mtROS ENSG00000162711 ENSG00000134326 ENSG00000125347 PMC8657754__F7 Lysine Acetylation in the Proteome of Renal Tubular Epithelial Cells in Diabetic Nephropathy ENSG00000149311 ENSG00000132906 ENSG00000291803 ENSG00000064012 ENSG00000164305 ENSG00000137801 PMC3871884__F8 Schematic diagram illustrating central role for ROS and Src in hypoxia-induced pY654-Beta-catenin/HIF1A formation and tumor EMT ENSG00000105329 ENSG00000291971 ENSG00000168036 ENSG00000146648 PMC11361850__F3 Mechanism by which mesenchymal stem cells-derived exosomes (MSCs-Exos) regulate the immune response ENSG00000162711 ENSG00000178607 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC9324584__F2 Translational Value of Tumor-Associated Lymphangiogenesis in Cholangiocarcinoma ENSG00000170962 ENSG00000186340 ENSG00000112715 ENSG00000137801 ENSG00000150630 PMC11361850__F6 Mechanism by which mesenchymal stem cells-derived exosomes (MSCs-Exos) promotes axonal growth and neuronal regeneration ENSG00000162711 ENSG00000110395 PMC11361850__F5 Mechanism by which mesenchymal stem cells-derived exosomes (MSCs-Exos) regulates apoptosis and autophagy ENSG00000141867 ENSG00000198793 ENSG00000175104 ENSG00000108840 PMC11672511__F1 Activation of the cGAS–STING signaling pathway by cytosolic mtDNA ENSG00000183735 ENSG00000164430 PMC5118094__F7 Cocaine regulation of specific Canonical Pathways at the mRNA level (left) and protein level (right) ENSG00000070831 ENSG00000291971 ENSG00000241553 ENSG00000163914 ENSG00000136997 ENSG00000162704 ENSG00000131196 PMC2923753__F2 Signalling pathways that regulate Candida albicansCHS gene expression ENSG00000101871 PMC11907960__F2 Key effector cells in radiation-induced lung injury ENSG00000198793 PMC11015576__F8 PREX2 contributes to radiation resistance by inhibiting radiotherapy-induced tumor immunogenicity via cGAS/STING/IFNs pathway in colorectal cancer ENSG00000183735 ENSG00000164430 ENSG00000046889 ENSG00000189403 PMC11688492__F2 The molecular mechanisms related to SARS-CoV-2 and S protein effect on vascular dysfunction and BBB disruption ENSG00000130234 ENSG00000125538 PMC11688492__F4 The molecular mechanisms related to astrocytes activation by the SARS-CoV-2 and S protein ENSG00000197635 ENSG00000100985 PMC9010946__F9 Comprehensive Analysis on Prognosis and Immune Infiltration of Lysyl Oxidase Family Members in Pancreatic Adenocarcinoma With Experimental Verification ENSG00000157404 ENSG00000213658 PMC11688492__F3 The molecular mechanisms related to microglia activation by the SARS-CoV-2 and S protein ENSG00000162711 ENSG00000150782 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000110218 PMC8310117__F2 SARS-CoV-2/Receptor Axis in Heart and Blood Vessels: A Crisp Update on COVID-19 Disease with Cardiovascular Complications ENSG00000110799 ENSG00000125538 ENSG00000184012 PMC4073990__F4 Schematic description of the signaling pathways known to be activated by CCK1R and CCK2R ENSG00000291971 ENSG00000113070 ENSG00000169047 ENSG00000198793 ENSG00000163914 ENSG00000168610 ENSG00000146648 PMC9354016__F2 The mucin-like glycoprotein FCGBP in mucosal immunity and cancer ENSG00000160180 ENSG00000113520 ENSG00000281123 ENSG00000293532 PMC5118094__F3 Environmental enrichment regulation of specific Canonical Pathways at the mRNA level (left) and protein level (right) ENSG00000114450 ENSG00000172380 ENSG00000156049 ENSG00000170214 ENSG00000078369 ENSG00000060558 ENSG00000176533 ENSG00000088256 ENSG00000174021 ENSG00000135914 ENSG00000242616 ENSG00000102468 ENSG00000010671 ENSG00000133019 ENSG00000196639 ENSG00000198049 ENSG00000069966 ENSG00000162188 ENSG00000186469 PMC1851929__F8 Proposed model for the activation of oligodendrocyte apoptosis by MHV infection ENSG00000171791 ENSG00000168040 ENSG00000026103 PMC6138873__F1 A model depicting cryptochrome signal transduction mechanisms in Arabidopsis PMC9092267__F8 De novo variants of CSNK2B cause a new intellectual disability-craniodigital syndrome by disrupting the canonical Wnt signaling pathway ENSG00000168036 ENSG00000161202 PMC6215617__F1 WNK pathway and major cancer-associated signaling pathways ENSG00000143867 ENSG00000118515 PMC7714562__F3 Overall depiction of the TRAF6-mediated signaling pathways ENSG00000239732 ENSG00000110395 ENSG00000291971 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC4723140__F2 Advanced Running Performance by Genetic Predisposition in Male Dummerstorf Marathon Mice (DUhTP) Reveals Higher Sterol Regulatory Element-Binding Protein (SREBP) Related mRNA Expression in the Liver and Higher Serum Levels of Progesterone ENSG00000169710 ENSG00000127884 PMC4723140__F1 Advanced Running Performance by Genetic Predisposition in Male Dummerstorf Marathon Mice (DUhTP) Reveals Higher Sterol Regulatory Element-Binding Protein (SREBP) Related mRNA Expression in the Liver and Higher Serum Levels of Progesterone ENSG00000143158 ENSG00000065243 PMC12152351__F6 miR-1236-3p targets Toll-like receptor 4 to suppress the anti-Mycobacterium tuberculosis activity of macrophage ENSG00000150782 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC3277127__F5 Curation of phosphoproteomic profiling and bioinformatics delineates distinct tyrosine kinase signaling pathways in an oncogene-specific manner ENSG00000157554 ENSG00000142627 ENSG00000120899 ENSG00000291971 ENSG00000198561 ENSG00000124181 ENSG00000168610 ENSG00000146648 ENSG00000196396 ENSG00000089159 PMC3061960__F5 NFKB activation in B cells ENSG00000186716 ENSG00000173039 ENSG00000136869 ENSG00000184216 ENSG00000198286 PMC9114699__F1 Thyroid Cancer and COVID-19: Prospects for Therapeutic Approaches and Drug Development ENSG00000157764 ENSG00000198793 PMC8744686__F4 Neurovascular Impairment and Therapeutic Strategies in Diabetic Retinopathy ENSG00000128272 PMC8902753__F2 Gut Microbiota in Inflammatory Bowel Disease ENSG00000162711 ENSG00000167207 ENSG00000121058 ENSG00000160703 ENSG00000174885 ENSG00000049768 ENSG00000096717 ENSG00000168610 PMC3524085__F7 Ingenuity pathway analysis of the 10-edge pattern subgraph showing cancer-associated interactions among its nodes ENSG00000005339 ENSG00000084676 ENSG00000173039 ENSG00000196498 ENSG00000168610 PMC8491225__F2 Biological role of metabolic reprogramming in pancreatic cancer ENSG00000125166 ENSG00000065833 PMC4723140__F3 Advanced Running Performance by Genetic Predisposition in Male Dummerstorf Marathon Mice (DUhTP) Reveals Higher Sterol Regulatory Element-Binding Protein (SREBP) Related mRNA Expression in the Liver and Higher Serum Levels of Progesterone ENSG00000160752 ENSG00000067064 ENSG00000110921 ENSG00000112972 ENSG00000172893 ENSG00000109929 ENSG00000113161 ENSG00000104549 ENSG00000167508 PMC8491225__F1 Biological role of metabolic reprogramming in pancreatic cancer ENSG00000198380 ENSG00000159399 PMC7749645__F1 Convergent type I interferon and proinflammatory cytokine pathways shared between SLE and COVID-19 ENSG00000183735 ENSG00000115415 ENSG00000134070 ENSG00000172936 ENSG00000131323 ENSG00000125347 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC3442981__F1 Metabolic pathways for 2,3-butanediol biosynthesis and pyruvate metabolism in S ENSG00000275544 PMC5607433__F5 Cytokine-cytokine receptor interaction ENSG00000110944 ENSG00000019991 ENSG00000081041 ENSG00000099985 ENSG00000214285 ENSG00000111321 ENSG00000145777 ENSG00000112715 ENSG00000226275 ENSG00000145839 ENSG00000135960 ENSG00000135409 ENSG00000128052 ENSG00000185591 ENSG00000026103 PMC6388767__F1 Bromouridine sequencing (Bru-seq) of MI-503 treated Ewing sarcoma cells identifies the SSP as a key oncogenic target ENSG00000065911 ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC4685484__F6 HMGB1-RAGE Inflammatory Pathway: Implications for Brain Injury-Induced Pulmonary Dysfunction ENSG00000189403 ENSG00000172936 ENSG00000150455 PMC5073880__F4 Diagram of pathways by which AGEs affect genes involved in steroid synthesis and follicular development ENSG00000170365 PMC4685484__F5 HMGB1-RAGE Inflammatory Pathway: Implications for Brain Injury-Induced Pulmonary Dysfunction ENSG00000111537 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC8662989__F1 Targeting hepatocyte carbohydrate transport to mimic fasting and calorie restriction ENSG00000143158 ENSG00000138030 ENSG00000136872 ENSG00000060762 PMC7805053__F4 Schematic diagram depicting IL17RD (Sef) modulation of the TIR signaling pathway ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC7547786__F2 Signaling pathways of IL-17A, pathological effect, and potential drug targets ENSG00000149968 ENSG00000163739 ENSG00000169429 ENSG00000100985 ENSG00000175104 ENSG00000163702 PMC7049061__F1 Bibliometric analysis flow chart of mTOR pathway in liver disease research ENSG00000147162 PMC5123862__F6 Polymerase exchange during TLS on the lagging strand ENSG00000108582 ENSG00000132646 ENSG00000130997 PMC7547786__F1 Th-17 cell polarization from naïve CD4+ T cells and activation ENSG00000162594 ENSG00000134982 ENSG00000112115 ENSG00000168610 ENSG00000069667 PMC11852866__F8 ITIH5-mediated fibroblast–macrophage crosstalk exacerbates cardiac remodelling after MI ENSG00000026508 ENSG00000118520 ENSG00000168610 PMC3107984__F3 Genetic analysis of biological pathway data through genomic randomization ENSG00000164039 ENSG00000083720 ENSG00000275544 ENSG00000117305 PMC9636403__F1 Identification of TCF1+ progenitor exhausted T cells in THRLBCL may predict a better response to PD-1/PD-L1 blockade ENSG00000168329 ENSG00000291603 ENSG00000198851 ENSG00000197646 ENSG00000171049 ENSG00000157601 ENSG00000185745 ENSG00000274736 ENSG00000185885 ENSG00000180644 ENSG00000121807 ENSG00000125347 ENSG00000183395 ENSG00000186810 ENSG00000224320 ENSG00000161921 ENSG00000185201 ENSG00000181374 ENSG00000276051 ENSG00000113263 PMC5295629__F4 Interactions of NIK wild-type and mutants ENSG00000000419 ENSG00000265681 ENSG00000140983 ENSG00000156709 ENSG00000105401 ENSG00000169710 ENSG00000148396 ENSG00000077150 ENSG00000143815 ENSG00000132382 ENSG00000125445 ENSG00000136758 ENSG00000102316 ENSG00000055044 ENSG00000247077 ENSG00000123983 ENSG00000253729 ENSG00000183605 ENSG00000135097 ENSG00000108298 ENSG00000146909 ENSG00000067057 ENSG00000183048 ENSG00000110107 ENSG00000163902 ENSG00000101361 ENSG00000107625 ENSG00000117906 ENSG00000001497 ENSG00000162408 ENSG00000136451 ENSG00000278270 ENSG00000127191 ENSG00000100320 ENSG00000177542 ENSG00000224320 ENSG00000004864 ENSG00000292099 ENSG00000102119 ENSG00000131323 ENSG00000105127 ENSG00000112306 ENSG00000102974 ENSG00000130726 PMC5295629__F1 Noncanonical NFKB signaling pathway ENSG00000104856 ENSG00000131323 ENSG00000127191 PMC2908766__F2 PI3K dependent signal pathway ENSG00000002330 ENSG00000198793 PMC5295629__F2 Interaction network of the noncanonical NFKB signaling pathway ENSG00000110330 ENSG00000265681 ENSG00000135451 ENSG00000105401 ENSG00000153165 ENSG00000189127 ENSG00000173905 ENSG00000112118 ENSG00000163820 ENSG00000168522 ENSG00000183735 ENSG00000090615 ENSG00000138768 ENSG00000159335 ENSG00000123983 ENSG00000183605 ENSG00000109670 ENSG00000023445 ENSG00000136485 ENSG00000108298 ENSG00000110107 ENSG00000126777 ENSG00000101361 ENSG00000001497 ENSG00000117906 ENSG00000278270 ENSG00000197601 ENSG00000135631 ENSG00000224320 ENSG00000004864 ENSG00000102119 ENSG00000131323 ENSG00000158545 ENSG00000130726 ENSG00000140983 ENSG00000099940 ENSG00000099910 ENSG00000143756 ENSG00000197451 ENSG00000115317 ENSG00000148396 ENSG00000092621 ENSG00000082512 ENSG00000076382 ENSG00000055044 ENSG00000247077 ENSG00000157540 ENSG00000109320 ENSG00000153201 ENSG00000173039 ENSG00000162924 ENSG00000127191 ENSG00000292099 PMC7407626__F4 Summary of intrinsic apoptotic pathway ENSG00000006712 ENSG00000166278 PMC12075242__F3 ETBF promotes tumorigenesis by distinct mechanisms ENSG00000145388 ENSG00000100410 ENSG00000102908 ENSG00000108773 ENSG00000136869 ENSG00000168610 PMC8227573__F1 An Insight into the microRNAs Associated with Arteriovenous and Cavernous Malformations of the Brain ENSG00000100234 ENSG00000166068 PMC7561614__F1 Metabolic pathway for squalene synthesis in oleaginous yeast ENSG00000122966 ENSG00000172005 ENSG00000197429 ENSG00000167508 PMC12075242__F5 Fn involved in immunotherapy ENSG00000196511 ENSG00000164430 PMC7349686__F2 Possible signaling mechanisms of ectopic osteogenesis in skeletal muscles ENSG00000170365 ENSG00000163235 ENSG00000168036 ENSG00000125968 ENSG00000108840 PMC7667972__F9 Glycerophosphodiesterase 3 (GDE3) is a lysophosphatidylinositol-specific ectophospholipase C acting as an endocannabinoid signaling switch ENSG00000100473 ENSG00000100523 ENSG00000134780 PMC3272823__F3 Involvement of the ERK pathway in the TGF-Beta-induced epithelial-mesenchymal transition ENSG00000019991 PMC8945730__F4 Epigallocatechin-3-Gallate (EGCG): New Therapeutic Perspectives for Neuroprotection, Aging, and Neuroinflammation for the Modern Age ENSG00000177169 ENSG00000152348 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC7849461__F2 Renin-angiotensin-aldosterone system ENSG00000130234 ENSG00000125538 PMC8040309__F3 FGL1-involved signaling pathways ENSG00000143799 ENSG00000089692 ENSG00000104760 ENSG00000198793 ENSG00000168610 PMC5410324__F1 PI3K pathway mutations are associated with longer time to local progression after radioembolization of colorectal liver metastases ENSG00000124102 ENSG00000157764 ENSG00000146648 PMC7710624__F7 Genetic and Physical Interaction Mapping Reveal New Facets of RAS Pathway Biology ENSG00000157927 ENSG00000006451 ENSG00000144118 PMC2745891__F6 Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mTOR activity and p27Kip1 localization ENSG00000198793 ENSG00000164690 ENSG00000128602 PMC2781394__F8 HGF-mediated inhibition of gluconeogenesis in primary hepatocytes ENSG00000019991 PMC6695538__F1 The crosstalk between estrogen receptor and growth factor receptor intracellular signaling pathways ENSG00000135446 ENSG00000198793 PMC4065383__F2 Origins and removal of ribonucleotides in DNA ENSG00000138346 ENSG00000132646 PMC11201890__F2 USP5 participates in immune regulation through a variety of signaling pathways ENSG00000162711 ENSG00000168036 ENSG00000175104 PMC2838378__F2 Simplified schematic of the T cell receptor signaling pathway ENSG00000213658 ENSG00000113263 PMC10380517__F2 CDK4/6 Inhibitor Resistance in Hormone Receptor-Positive Metastatic Breast Cancer: Translational Research, Clinical Trials, and Future Directions ENSG00000135446 ENSG00000198793 ENSG00000105810 ENSG00000077782 PMC2838378__F1 Simplified schematic of the IgE receptor (FcERI) signaling pathway ENSG00000213658 ENSG00000010810 ENSG00000086730 PMC8269036__F2 mRNA-miRNA-lncRNA Regulatory Network in Nonalcoholic Fatty Liver Disease ENSG00000186575 ENSG00000114019 ENSG00000074219 PMC11946680__F7 Action induced by 3-MCPD ENSG00000137275 ENSG00000168404 ENSG00000285379 PMC5108628__F1 Nucleic acid sensing and innate immunity: signaling pathways controlling viral pathogenesis and autoimmunity ENSG00000184979 ENSG00000183735 ENSG00000088888 ENSG00000160710 ENSG00000168040 ENSG00000102172 PMC6911338__F7 Schematic diagram of miR-155 intercellular transport and activation of mTOR signaling pathway ENSG00000198793 ENSG00000155792 PMC5524291__F9 An essential EBV latent antigen 3C binds Bcl6 for targeted degradation and cell proliferation ENSG00000137265 ENSG00000171791 PMC3795364__F6 Schematic presentation of the influence of angiogenesis inhibitors on EC signaling ENSG00000186810 ENSG00000198793 ENSG00000163737 PMC11568081__F5 Figure illustrates the mechanism by which kaempferol enhances sensitivity to anti-digestive system tumor drugs ENSG00000011304 ENSG00000168610 ENSG00000146648 PMC8584162__F2 Defining Pathological Activities of ALK in Neuroblastoma, a Neural Crest-Derived Cancer ENSG00000169291 ENSG00000150672 ENSG00000291971 ENSG00000244405 ENSG00000169047 ENSG00000105639 ENSG00000168610 PMC11568081__F4 Figure shows how kaempferol suppresses metastasis and invasion while inducing autophagy in digestive system tumors ENSG00000291971 ENSG00000198793 ENSG00000145782 ENSG00000146648 ENSG00000057663 PMC11568081__F3 Figure illustrates how kaempferol inhibits digestive system tumors cell proliferation ENSG00000188486 ENSG00000149311 ENSG00000011304 ENSG00000134057 PMC11568081__F2 Figure illustrates how kaempferol induces apoptosis in digestive system tumors ENSG00000111012 ENSG00000162711 ENSG00000100290 ENSG00000002330 ENSG00000177606 ENSG00000026103 PMC9465383__F1 Reprogramming lipid metabolism as potential strategy for hematological malignancy therapy ENSG00000135218 ENSG00000130164 ENSG00000102226 ENSG00000198793 ENSG00000169710 ENSG00000173334 PMC9329679__F1 Critical Appraisal of Filgotinib in the Treatment of Ulcerative Colitis: Current Evidence and Place in Therapy ENSG00000213928 ENSG00000105397 PMC2424235__F1 Auxin signaling ENSG00000100387 ENSG00000111530 PMC4935211__F1 Schematic diagram of TRAIL-induced apoptotic signaling cascades ENSG00000168040 PMC5593678__F2 Autophagy in hepatocellular carcinoma: friend or foe ENSG00000128272 ENSG00000144895 ENSG00000146648 ENSG00000175857 PMC5768349__F4 Identification of novel genes in aging osteoblasts using next-generation sequencing and bioinformatics ENSG00000154342 ENSG00000182968 ENSG00000159224 ENSG00000151012 ENSG00000142178 ENSG00000165891 ENSG00000118263 ENSG00000176887 ENSG00000170558 ENSG00000124766 ENSG00000111696 ENSG00000181690 ENSG00000168938 ENSG00000196628 ENSG00000128218 ENSG00000164061 ENSG00000066044 ENSG00000108405 ENSG00000067191 ENSG00000158427 ENSG00000182389 ENSG00000163788 PMC5768349__F7 Identification of novel genes in aging osteoblasts using next-generation sequencing and bioinformatics ENSG00000129474 ENSG00000127328 ENSG00000153823 ENSG00000132478 ENSG00000169242 ENSG00000075213 ENSG00000048740 ENSG00000151388 PMC5618569__F2 Schematic representation of the cytoplasmic and nuclear functions of the autophagy—related factors Beclin-1, LC3B and p62 ENSG00000163961 ENSG00000198793 ENSG00000140464 PMC3794382__F1 Gene sets are not pathways ENSG00000170458 ENSG00000130159 ENSG00000175104 ENSG00000127191 ENSG00000026103 PMC5618569__F1 Stages of autophagy ENSG00000177169 ENSG00000083290 ENSG00000140464 PMC2783241__F2 Kidney development: from ureteric bud formation to branching morphogenesis ENSG00000019991 ENSG00000164056 ENSG00000138798 ENSG00000107485 PMC6335102__F8 ANG II induces cardiac hypertrophy by multiple means involving direct actions on cardiac myocytes (cm) or the release of paracrine factors from other cell types, such as endothelial cells and fibroblasts/myofibroblasts ENSG00000175054 ENSG00000133107 ENSG00000105835 ENSG00000198053 ENSG00000144935 ENSG00000291971 ENSG00000198793 ENSG00000086991 ENSG00000146648 PMC6335102__F7 ANG II signaling and vascular fibrosis ENSG00000113070 ENSG00000118520 ENSG00000146648 PMC9464936__F3 Know when to fold ‘em: Polycomb complexes in oncogenic 3D genome regulation ENSG00000198901 ENSG00000163930 ENSG00000183337 ENSG00000085185 PMC7439504__F6 Beyond the cell factory: Homeostatic regulation of and by the UPRER ENSG00000150907 ENSG00000171791 ENSG00000127191 PMC9284233__F2 Glycolysis in Innate Immune Cells Contributes to Autoimmunity ENSG00000182578 ENSG00000183735 ENSG00000137265 ENSG00000126353 ENSG00000118520 ENSG00000168610 ENSG00000159399 PMC8847744__F5 Intestinal Infection of Candida albicans: Preventing the Formation of Biofilm by C. albicans and Protecting the Intestinal Epithelial Barrier ENSG00000002330 ENSG00000115415 ENSG00000168610 PMC5193387__F4 Harnessing cancer cell metabolism for theranostic applications using metabolic glycoengineering of sialic acid in breast cancer as a pioneering example ENSG00000159921 ENSG00000135838 ENSG00000100473 ENSG00000147162 ENSG00000145321 ENSG00000102032 ENSG00000146648 PMC6861177__F1 Mitochondrial quality control ENSG00000106459 PMC10390316__F1 Cellular mechanisms of fibrin (ogen): insight from neurodegenerative diseases ENSG00000169245 ENSG00000108691 ENSG00000146648 PMC12125403__F4 Posttranslational modification of NLRP3 inflammasome components via ubiquitination and deubiquitination ENSG00000162711 ENSG00000213186 ENSG00000185515 ENSG00000186480 ENSG00000189401 ENSG00000285152 ENSG00000228623 ENSG00000170242 ENSG00000116525 ENSG00000086758 ENSG00000124356 ENSG00000141569 ENSG00000135093 ENSG00000101557 ENSG00000145604 ENSG00000118503 ENSG00000122779 ENSG00000165819 PMC12125403__F1 Transcriptional regulation of NLRP3 expression ENSG00000162711 ENSG00000163435 ENSG00000135218 ENSG00000102908 ENSG00000010810 ENSG00000198793 ENSG00000168040 ENSG00000106546 PMC4528364__F8 Conserved mechanism of TOR-dependent RCK-mediated mRNA degradation regulates autophagy ENSG00000152348 ENSG00000126775 ENSG00000144848 ENSG00000172795 PMC5925455__F7 Hypothetical model for the aggravation of autoimmune response in Pdmx-associated and spontaneous NT1.The immune response in NT1 is highly heterogenic with different pathways affected during the disease progression ENSG00000103811 ENSG00000111537 ENSG00000244165 PMC8424797__F2 LncRNAs and circRNAs in the PD-1/PD-L1 pathway in cancer immunotherapy ENSG00000117020 ENSG00000138336 ENSG00000173039 ENSG00000276043 PMC8424797__F1 LncRNAs and circRNAs in the PD-1/PD-L1 pathway in cancer immunotherapy ENSG00000213928 ENSG00000150907 PMC8424797__F3 LncRNAs and circRNAs in the PD-1/PD-L1 pathway in cancer immunotherapy ENSG00000091317 ENSG00000183723 ENSG00000164362 PMC3405855__F5 Models of apoptosis-induced proliferation in mammals ENSG00000168040 PMC7543933__F2 IFN-Alpha-driven pDC-B cells crosstalk leading to antibody production in response to viral infection ENSG00000236637 ENSG00000125538 ENSG00000172936 ENSG00000184216 PMC6279409__F2 Sensing danger through a “finger” ENSG00000172936 PMC9697017__F6 Integrating Network Pharmacology and Transcriptomic Strategies to Explore the Pharmacological Mechanism of Hydroxysafflor Yellow A in Delaying Liver Aging ENSG00000124102 ENSG00000130528 ENSG00000122966 ENSG00000156026 ENSG00000121058 ENSG00000198168 ENSG00000160741 ENSG00000180210 ENSG00000262634 ENSG00000172005 ENSG00000115263 ENSG00000188404 ENSG00000127948 ENSG00000167701 PMC7404278__F1 Molecular switches regulating hair growth ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC6921965__F1 DSB repair pathways in mammalian cells ENSG00000012048 ENSG00000051180 ENSG00000177084 PMC2500163__F4 HIV Replication Enhances Production of Free Fatty Acids, Low Density Lipoproteins and Many Key Proteins Involved in Lipid Metabolism: A Proteomics Study ENSG00000147604 ENSG00000026103 PMC8780133__F3 N-Methyl-D-Aspartate Receptors (NMDARs) in Epilepsy ENSG00000137672 ENSG00000105662 PMC8429596__F1 Translational Potential of RNA Derived From Extracellular Vesicles in Multiple Myeloma ENSG00000178860 ENSG00000261857 ENSG00000163739 ENSG00000242866 ENSG00000078098 PMC9440251__F6 Nintedanib induces a senolytic effect in senescent HDFs via JAK2/STAT3 pathway ENSG00000123374 ENSG00000168610 PMC4045488__F1 MicroRNAs in pancreatic cancer metabolism ENSG00000083857 ENSG00000135218 PMC8615627__F2 LncRNAs: Novel Biomarkers for Pancreatic Cancer ENSG00000264522 ENSG00000138798 ENSG00000168610 ENSG00000146648 ENSG00000251493 PMC8615627__F1 LncRNAs: Novel Biomarkers for Pancreatic Cancer ENSG00000170365 ENSG00000106683 ENSG00000163914 ENSG00000156574 ENSG00000175104 PMC8187363__F3 Involvement of accessory proteins in diseases ENSG00000033327 ENSG00000291603 ENSG00000291971 ENSG00000140575 ENSG00000186716 ENSG00000022267 ENSG00000108061 PMC8187363__F2 Involvement of RTK-RAS-MAPK accessory proteins in signal transduction ENSG00000291603 ENSG00000110395 ENSG00000181163 ENSG00000140575 ENSG00000112851 ENSG00000198670 ENSG00000022267 ENSG00000166068 ENSG00000111816 ENSG00000108061 PMC8102505__F1 Autophagy pathway ENSG00000177169 ENSG00000110497 ENSG00000152348 ENSG00000198382 ENSG00000126775 ENSG00000144848 ENSG00000284099 ENSG00000157954 ENSG00000099940 ENSG00000175104 ENSG00000145782 ENSG00000136874 PMC9582647__F1 Plasma membrane and brain dysfunction of the old: Do we age from our membranes? ENSG00000125538 ENSG00000169047 ENSG00000198793 ENSG00000136869 ENSG00000115594 PMC4377510__F5 Possible transforming pathway ENSG00000168036 ENSG00000185104 ENSG00000026103 PMC4801113__F2 Iron homeostasis in host defence and inflammation ENSG00000010704 ENSG00000106327 ENSG00000187045 ENSG00000105697 ENSG00000168610 ENSG00000204217 PMC2962793__F1 a, b Bioactive eicosanoids derived from the arachidonic acid cascade PMC4404183__F2 Natural history of Beta-cell adaptation and failure in type 2 diabetes ENSG00000019991 ENSG00000139287 ENSG00000129167 ENSG00000150907 ENSG00000169047 ENSG00000187140 ENSG00000168036 ENSG00000140443 ENSG00000113494 PMC7222158__F3 Gene network of regulation of synaptic transmission, glutamatergic (obtained using Pathway Studio v ENSG00000169432 ENSG00000073756 PMC1297571__F6 Simplified diagram of the proposed signalling events leading to Cyp7b gene transcription in synovial fibroblasts ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC2962793__F2 Cytochrome P450 epoxygenase expression in tumor cell compartments and their potential role in cell–cell communication in the tumor stroma ENSG00000138115 ENSG00000134716 PMC3619152__F10 Proposed pathway showing increased Nox4 expression and H2O2 levels in PPHN PA, leading to a decreased ecSOD activity and vasoconstriction, and increased NFKB and cyclin D1 leading to pulmonary vascular remodeling ENSG00000086991 PMC7824059__F4 Top-ranked and interested pathways in Holstein and Jersey cows ENSG00000182533 ENSG00000081041 ENSG00000108179 ENSG00000041982 ENSG00000100906 ENSG00000102871 ENSG00000125538 ENSG00000163734 ENSG00000108405 ENSG00000157625 ENSG00000175104 ENSG00000073756 PMC8228851__F1 Interleukin 11 (IL-11): Role(s) in Breast Cancer Bone Metastases ENSG00000137070 ENSG00000198793 PMC3734218__F1 Roles of Genetic Polymorphisms in the Folate Pathway in Childhood Acute Lymphoblastic Leukemia Evaluated by Bayesian Relevance and Effect Size Analysis ENSG00000284320 ENSG00000228716 ENSG00000100714 ENSG00000137364 ENSG00000205221 ENSG00000173638 ENSG00000136877 ENSG00000124275 ENSG00000137563 ENSG00000116984 PMC5584184__F3 Postendocytic sorting of receptors along the endolysosomal pathway ENSG00000124102 ENSG00000102189 ENSG00000157500 ENSG00000111737 PMC4002842__F2 Network analysis of expression profiles of 10 μmol/L AA in HK-2 cells ENSG00000188786 ENSG00000134339 ENSG00000123240 ENSG00000101000 ENSG00000169047 ENSG00000072274 ENSG00000127528 ENSG00000111321 ENSG00000175567 ENSG00000180644 ENSG00000104368 ENSG00000163631 ENSG00000269404 ENSG00000185591 ENSG00000105246 ENSG00000135919 ENSG00000148346 ENSG00000104899 ENSG00000081041 ENSG00000143549 ENSG00000129226 ENSG00000105639 ENSG00000276561 ENSG00000276068 ENSG00000071564 ENSG00000019582 ENSG00000226275 ENSG00000167468 ENSG00000049249 ENSG00000115009 PMC4424395__F6 Signaling pathways associated with litter size in boars ENSG00000123545 ENSG00000113520 ENSG00000104388 ENSG00000120160 ENSG00000146701 ENSG00000149187 PMC7653868__F2 Yellow nodes represent genes enriched in Infiltrating Ductal carcinoma of breast identified by Pathway enrichment ENSG00000197747 ENSG00000109452 ENSG00000163930 ENSG00000163939 ENSG00000181788 ENSG00000184347 ENSG00000075142 ENSG00000108819 ENSG00000072364 ENSG00000064300 ENSG00000171720 ENSG00000186340 ENSG00000091844 ENSG00000196914 ENSG00000072422 ENSG00000166803 ENSG00000130827 ENSG00000131473 ENSG00000123091 ENSG00000018408 ENSG00000168610 ENSG00000094804 ENSG00000114268 ENSG00000115808 ENSG00000136448 ENSG00000145819 ENSG00000143924 PMC7653868__F1 Reactome FI network ENSG00000197747 ENSG00000163930 ENSG00000163939 ENSG00000181788 ENSG00000184347 ENSG00000131503 ENSG00000108654 ENSG00000181555 ENSG00000091106 ENSG00000064300 ENSG00000012048 ENSG00000171720 ENSG00000150991 ENSG00000084676 ENSG00000186340 ENSG00000156299 ENSG00000175832 ENSG00000091844 ENSG00000185591 ENSG00000022267 ENSG00000196914 ENSG00000072422 ENSG00000124181 ENSG00000166803 ENSG00000131473 ENSG00000123091 ENSG00000144791 ENSG00000131023 ENSG00000160691 ENSG00000115760 ENSG00000094804 ENSG00000065978 ENSG00000010810 ENSG00000177606 ENSG00000114268 ENSG00000047849 ENSG00000115808 ENSG00000136448 ENSG00000143924 PMC8988011__F7 Small molecule LATS kinase inhibitors block the Hippo signaling pathway and promote cell growth under 3D culture conditions ENSG00000150457 ENSG00000131023 PMC5632348__F6 Schematic illustration of the TLR4 signaling pathway (a) and inhibition via TAK-242 (b) ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC7653868__F3 Pathway in FI sub-network ENSG00000163930 ENSG00000181788 ENSG00000181555 ENSG00000018408 ENSG00000091106 ENSG00000144791 ENSG00000131023 ENSG00000168610 ENSG00000064300 ENSG00000160691 ENSG00000012048 ENSG00000171720 ENSG00000084676 ENSG00000175832 ENSG00000196914 ENSG00000145819 PMC7293352__F3 Inositol phosphate and phosphatidylinositol signaling pathways in metazoans ENSG00000124102 ENSG00000141401 ENSG00000151151 PMC3596735__F5 Mechanism of response to anti-EGFR inhibitors ENSG00000157764 ENSG00000146648 PMC3596735__F3 ERK/MEK pathway ENSG00000172680 ENSG00000002330 ENSG00000070831 ENSG00000065361 ENSG00000010810 ENSG00000067606 ENSG00000143226 PMC8359944__F1 Structural Basis of Prolyl Hydroxylase Domain Inhibition by Molidustat ENSG00000091879 ENSG00000112715 ENSG00000084774 PMC4076992__F2 Endoplasmic Reticulum Stress and Oxidative Stress in Cell Fate Decision and Human Disease ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC12056223__F7 Schematic summary of the role of targeting Dnmt3a mediated ID2 promoter in MMT PMC10636769__F2 IORT regulates the proliferation of microRNA-223, thereby reducing EGF levels and ultimately attenuating the EGFR signaling pathway ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC4474537__F4 BMRF-MI: integrative identification of protein interaction network by modeling the gene dependency ENSG00000182481 ENSG00000002330 ENSG00000070831 ENSG00000291971 ENSG00000105401 ENSG00000134308 ENSG00000147133 ENSG00000073111 ENSG00000187266 ENSG00000099942 ENSG00000121966 ENSG00000089159 ENSG00000197063 ENSG00000105894 ENSG00000117154 ENSG00000143801 ENSG00000084676 ENSG00000128052 ENSG00000143379 ENSG00000071051 ENSG00000178719 ENSG00000132535 ENSG00000125834 ENSG00000170027 ENSG00000081237 ENSG00000126457 ENSG00000169242 ENSG00000135624 ENSG00000064995 ENSG00000160691 ENSG00000100632 ENSG00000164404 ENSG00000175166 ENSG00000010810 ENSG00000186716 ENSG00000129152 ENSG00000188130 ENSG00000132341 PMC6947309__F1 Stimulation of a particular TLR by DAMPs and activation of the IL-1 pathway via stimulation of IL-1R ENSG00000172936 ENSG00000175104 PMC5668000__F6 Beta-catenin represses protein kinase D1 gene expression by non-canonical pathway through MYC/MAX transcription complex in prostate cancer ENSG00000136997 ENSG00000168036 ENSG00000184304 PMC7800773__F1 Combination therapies for MPNSTs targeting RABL6A-RB1 signaling ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000139687 PMC8954347__F1 LncRNA: A Potential Target for Host-Directed Therapy of Candida Infection ENSG00000239732 ENSG00000187796 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC3734242__F8 Role of PTPA in the Destruction of Periodontal Connective Tissues ENSG00000102871 ENSG00000291971 ENSG00000125538 ENSG00000172936 ENSG00000119383 ENSG00000175104 ENSG00000127191 PMC8630816__F3 MCP-1 targeting: Shutting off an engine for tumor development ENSG00000137033 ENSG00000291971 ENSG00000198793 ENSG00000168610 PMC3742868__F11 Proposed scheme for the role of mTOR in p53-induced kidney cell injury ENSG00000026103 PMC5417715__F2 Drosophila as a model for homeostatic, antibacterial, and antiviral mechanisms in the gut ENSG00000136807 ENSG00000124733 ENSG00000168610 ENSG00000146648 PMC4324555__F5 CREB and the CRTC co-activators: sensors for hormonal and metabolic signals ENSG00000130699 ENSG00000170145 ENSG00000160741 PMC5733538__F6 The positive feedback regulation between transglutaminase 2 (TGM2) and TLR4 signaling in hepatic stellate cells (HSCs) activation and liver fibrosis ENSG00000169245 ENSG00000170458 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000184216 PMC5400276__F3 Chemical Reaction Network Theory elucidates sources of multistability in interferon signaling ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC8861086__F3 Negative Regulation of the IL-1 System by IL-1R2 and IL-1R8: Relevance in Pathophysiology and Disease ENSG00000137033 ENSG00000198793 ENSG00000136694 ENSG00000172936 PMC8438545__F2 Evaluation of the molecular response of corpora lutea to manganese–amino acid complex supplementation in gilts ENSG00000160752 ENSG00000110921 ENSG00000132196 ENSG00000116133 ENSG00000172893 ENSG00000149809 ENSG00000113161 ENSG00000104549 ENSG00000166278 ENSG00000120437 ENSG00000167508 PMC8977492__F2 Adenosine-A2A Receptor Pathway in Cancer Immunotherapy ENSG00000196839 PMC1397816__F2 Activation of canonical Wnt signalling pathway in the presence of Wnt signals ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC1397816__F1 Inhibition of canonical Wnt signalling pathway in the absence of Wnt signals ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11686125__F5 Related target action relationship between QJ and the HIF-1 signaling pathway ENSG00000134086 ENSG00000074800 ENSG00000100387 ENSG00000198793 ENSG00000136869 ENSG00000168610 PMC1397816__F5 Inhibition of Wnt signalling by a Fz-dependent pathway ENSG00000087095 ENSG00000281324 ENSG00000162337 PMC6737011__F9 Metabolism in WSSV-infected hemocytes showing the aerobic glycolysis, glutamine metabolism and lipogenesis pathways at the WSSV genome replication stage (12 hpi) ENSG00000122966 ENSG00000172005 ENSG00000115419 ENSG00000062485 PMC4358823__F2 Human prostate cancer vaccines – proposed mechanisms of action and future combinatorial treatment strategies PMC4358823__F1 Human prostate cancer vaccines – proposed mechanisms of action and future combinatorial treatment strategies ENSG00000116815 PMC4768650__F4 Interleukin-5 plays a fundamental role in the proliferation, maturation in the bone marrow, recruitment and activation at sites of allergic inflammation of eosinophils ENSG00000197971 ENSG00000121053 PMC9697478__F13 Immunomodulatory Effects of an Aqueous Extract of Black Radish on Mouse Macrophages via the TLR2/4-Mediated Signaling Pathway ENSG00000136869 ENSG00000168610 PMC4768650__F3 Eosinophils modulate the functions of a multitude of cells of the innate and adaptive immune system ENSG00000197971 ENSG00000102970 ENSG00000105656 ENSG00000121053 PMC4768650__F2 Eosinophils contain and/or release a wide array of preformed and de novo synthesized mediators important for their effector functions ENSG00000169248 ENSG00000108691 ENSG00000111537 ENSG00000163739 ENSG00000197971 ENSG00000125538 ENSG00000138755 ENSG00000102970 ENSG00000274736 ENSG00000169429 ENSG00000112715 ENSG00000121053 PMC3667593__F5 Abbreviated Pluripotent Cell Cycle ENSG00000100811 ENSG00000172273 ENSG00000135446 ENSG00000123374 ENSG00000185591 ENSG00000168310 ENSG00000105810 ENSG00000123268 PMC9235300__F2 Telocytes in Fibrosis Diseases: From Current Findings to Future Clinical Perspectives ENSG00000019991 ENSG00000100422 ENSG00000274336 ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000146374 PMC7140616__F2 Activation of the canonical Wnt pathway in head and neck cancers is mediated by various factors ENSG00000172269 ENSG00000138798 ENSG00000168036 ENSG00000146648 ENSG00000163507 PMC7222158__F2 Gene network of positive regulation of fat cell differentiation (obtained using Pathway Studio v ENSG00000073756 PMC7140616__F1 Fates of Beta-catenin, when the canonical Wnt pathway is not activated ENSG00000083857 ENSG00000156076 ENSG00000134982 ENSG00000168036 PMC3404043__F3 Whole Transcriptome Analysis of the Effects of Type I Diabetes on Mouse Oocytes ENSG00000145604 ENSG00000124102 ENSG00000108055 ENSG00000213658 ENSG00000122966 ENSG00000132646 ENSG00000123374 ENSG00000164754 ENSG00000277273 ENSG00000127948 ENSG00000164778 PMC7072240__F6 Cooperative regulation of genes involved in glutathione (GSH) and NADPH synthesis by Nrf2 and ATF4 ENSG00000065911 ENSG00000128272 ENSG00000100714 ENSG00000092621 ENSG00000135069 ENSG00000146733 ENSG00000023909 ENSG00000070669 ENSG00000116761 PMC7523021__F2 Integration of networks of SFH targets ENSG00000196296 ENSG00000291603 ENSG00000002330 ENSG00000170214 ENSG00000138798 ENSG00000181104 ENSG00000169047 ENSG00000171791 ENSG00000127191 ENSG00000102468 ENSG00000274542 ENSG00000007171 ENSG00000133019 ENSG00000213658 ENSG00000128052 ENSG00000177606 ENSG00000146648 PMC10505605__F1 Extranodal lymphoma: pathogenesis, diagnosis and treatment ENSG00000105369 ENSG00000007312 ENSG00000186716 ENSG00000198793 ENSG00000136997 ENSG00000172936 ENSG00000171791 ENSG00000184216 ENSG00000010671 ENSG00000198286 ENSG00000026103 PMC5928506__F8 MSC PGE2 secretion reprograms M1 via two independent pathways to M2 macrophages ENSG00000105723 PMC3272847__F2 E6-mediated survival signaling ENSG00000198793 ENSG00000146648 PMC7862665__F2 E3 ubiquitin ligases in the development and progression of glioblastoma ENSG00000154370 ENSG00000132109 ENSG00000067057 ENSG00000168036 ENSG00000079432 ENSG00000168610 ENSG00000120696 ENSG00000110395 ENSG00000081913 ENSG00000100505 ENSG00000010810 ENSG00000175104 ENSG00000122779 ENSG00000146648 ENSG00000196712 PMC4294344__F1 Bioinformatics analysis of the serine and glycine pathway in cancer cells ENSG00000284320 ENSG00000135423 ENSG00000092621 ENSG00000146733 ENSG00000178445 PMC7734287__F8 Mechanism for Forkhead box Q1 (FOXQ1) induced angiogenesis and macrophage infiltration in colorectal cancer (CRC) tumorigenesis ENSG00000164379 ENSG00000167772 ENSG00000108691 ENSG00000011422 ENSG00000122691 ENSG00000113070 ENSG00000138798 ENSG00000091879 ENSG00000154188 ENSG00000135605 PMC4065761__F1 Current models of the signaling pathway of the spindle assembly checkpoint (SAC) ENSG00000171444 ENSG00000134982 ENSG00000117399 PMC9608318__F2 Comparative Upper Respiratory Tract Transcriptomic Profiling Reveals a Potential Role of Early Activation of Interferon Pathway in Severe COVID-19 ENSG00000134321 ENSG00000187608 ENSG00000185745 ENSG00000142166 PMC3717945__F3 Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance ENSG00000177169 ENSG00000169291 ENSG00000169047 ENSG00000198793 ENSG00000155792 ENSG00000196712 PMC4749963__F2 A Trans-omics Mathematical Analysis Reveals Novel Functions of the Ornithine Metabolic Pathway in Cancer Stem Cells ENSG00000116649 ENSG00000102172 PMC4838361__F5 PARI regulates the repair of single-strand gaps left behind the replication fork ENSG00000187790 PMC5249001__F3 Pathway Studio guided network that describes regulatory connections between the deregulation of Aurora kinases, caspase-3 and osteopontin-encoding SPP1 ENSG00000170561 ENSG00000152192 ENSG00000118785 ENSG00000178999 ENSG00000087586 ENSG00000112715 ENSG00000164305 PMC10040566__F2 Th-17 cells and IL-17 in the metastatic spread of breast cancer: As a means of prognosis and therapeutic target ENSG00000123342 ENSG00000175104 ENSG00000163702 ENSG00000150630 PMC7930745__F3 TMEM16A regulates cancer cell proliferation ENSG00000170558 PMC5559791__F4 This adipogenic gene network is centered on the up-regulated transcription factor CEBPA and interactions with several other transcription regulators (a) ENSG00000182481 ENSG00000151726 ENSG00000135218 ENSG00000117228 ENSG00000102753 ENSG00000188729 ENSG00000155792 ENSG00000169710 ENSG00000127528 ENSG00000205250 ENSG00000171791 ENSG00000062282 ENSG00000053372 ENSG00000163631 ENSG00000245848 ENSG00000106683 ENSG00000167107 ENSG00000160563 ENSG00000108821 ENSG00000283060 ENSG00000109670 PMC5559791__F3 Interactions of two transcription factors (PPARG and PPARD) and their direct target genes that control lipid metabolism in abdominal fat of juvenile HG and LG chickens ENSG00000168028 ENSG00000151726 ENSG00000059804 ENSG00000153823 ENSG00000008394 ENSG00000146477 ENSG00000169710 ENSG00000171791 ENSG00000122194 ENSG00000062282 ENSG00000137801 ENSG00000053372 ENSG00000132170 ENSG00000130304 ENSG00000245848 ENSG00000159720 ENSG00000186340 ENSG00000132855 ENSG00000106624 ENSG00000282941 ENSG00000124253 ENSG00000114520 ENSG00000164830 ENSG00000274137 PMC7606919__F1 Resistance to immunotherapy ENSG00000101751 ENSG00000089692 ENSG00000181847 ENSG00000163235 ENSG00000160710 ENSG00000273686 PMC1838573__F1 Mitochondrial pathway through Bcl-2 family members ENSG00000002330 ENSG00000102871 ENSG00000056558 ENSG00000168040 ENSG00000127191 PMC6106745__F2 Viral carcinogenesis pathway and differentially expressed genes in primary NSCLC tumors ENSG00000179934 ENSG00000070831 ENSG00000183625 ENSG00000130402 PMC5559791__F6 Ingenuity Pathway Analysis of RNA-Seq data showed that the canonical coagulation system was over-represented by up-regulated genes in abdominal fat of LG cockerels ENSG00000003436 ENSG00000133116 PMC9162453__F1 Heme biosynthetic pathway ENSG00000135776 ENSG00000144410 ENSG00000066926 ENSG00000126088 ENSG00000172005 ENSG00000256269 ENSG00000188690 ENSG00000146147 PMC6409413__F7 miR-582-3p and miR-582-5p Suppress Prostate Cancer Metastasis to Bone by Repressing TGFB Signaling ENSG00000136535 ENSG00000111859 ENSG00000112715 ENSG00000137801 PMC7898953__F1 Extra-cellular and intra-cellular signalling regulating cardiomyocyte proliferation and cardiac regeneration ENSG00000135446 ENSG00000168036 ENSG00000123374 ENSG00000128342 ENSG00000150457 ENSG00000131023 PMC9027139__F1 O-linked N-acetylglucosamine (O-GlcNAc) modification of proteins in diabetic cardiovascular complications ENSG00000147162 ENSG00000156958 ENSG00000124357 PMC6072467__F4 Synthesis and growth-inhibitory activities of imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamides ENSG00000090402 PMC2675552__F3 Mechanism of action of toll-like receptors (TLRs) ENSG00000174125 ENSG00000136869 PMC9533025__F4 Estrogens, estrogen-like compounds, and endocrine disruptors in adipocytes ENSG00000115457 ENSG00000105550 ENSG00000116985 ENSG00000169752 ENSG00000130513 PMC5798243__F1 Physiological events post-BCG exposure: UC cell exposure to BCG results in A5B1 receptor mediated BCG internalization involving A5B1cross linking ENSG00000163739 ENSG00000163734 PMC11174684__F5 Schematic representation of the hypothetical signaling pathway activated under PEG-6000 treatment in Saragolla and Svevo cultivars ENSG00000105722 ENSG00000069956 PMC12232514__F3 Non‐caloric artificial sweeteners on gut health ENSG00000187554 ENSG00000172936 ENSG00000005381 PMC5821620__F1 Bidirectional E-cadherin/catenin–EGFR cross talk in epithelial biology ENSG00000291971 ENSG00000198793 ENSG00000168036 PMC11063508__F1 Schematic diagram of the entire study ENSG00000175054 ENSG00000134057 ENSG00000135446 ENSG00000123374 ENSG00000075218 ENSG00000164305 ENSG00000198625 ENSG00000175305 PMC10034053__F2 Immune cells and immune cell-targeted therapy in chronic pancreatitis ENSG00000157601 ENSG00000112115 PMC4539082__F2 Clinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathway PMC7290813__F7 Graphical representation of selected intracellular effects and induction of apoptosis in mammalian cells following internalization of Shiga toxin holotoxins (Stx) ENSG00000162711 ENSG00000006712 ENSG00000084774 PMC6515079__F9 Network analysis of proteome datasets in M1 polarized (vs ENSG00000168028 ENSG00000144485 ENSG00000186395 ENSG00000188822 ENSG00000170027 ENSG00000113318 ENSG00000088247 ENSG00000108654 ENSG00000092199 ENSG00000291420 PMC8017486__F1 The design and application of AE@NPs for enhanced PC treatment ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC11257078__F1 Species differences in bile acid synthesis ENSG00000167910 ENSG00000180432 ENSG00000135929 PMC7290813__F8 Graphical representation of effects in mammalian cells following binding of Shiga toxin (Stx) B subunits to cell surface receptors ENSG00000162711 ENSG00000110799 ENSG00000006712 ENSG00000186716 PMC7303777__F2 Insulin signaling pathway ENSG00000171105 ENSG00000002330 ENSG00000073578 ENSG00000005882 ENSG00000150907 ENSG00000198793 ENSG00000026103 PMC11257078__F4 Bile acid crosstalk with sulfur amino acid metabolism ENSG00000129596 ENSG00000167910 PMC11257078__F3 Bile acid regulation of the autophagy-lysosome axis ENSG00000107798 ENSG00000198793 ENSG00000112561 ENSG00000057663 PMC5854681__F1 Differential control of distinct stages in adult SVZ-OB neurogenesis by different cell cycle regulatory proteins ENSG00000168283 ENSG00000135547 ENSG00000171720 ENSG00000123374 ENSG00000205250 ENSG00000105810 PMC5517153__F1 Pathway for thiopurine metabolism ENSG00000137364 PMC7898953__F5 Effect of miRNAs on the Hippo pathway and the actin cytoskeleton ENSG00000070087 ENSG00000211455 ENSG00000160551 ENSG00000243156 ENSG00000170558 ENSG00000166025 ENSG00000168036 ENSG00000151239 ENSG00000150457 ENSG00000131023 PMC8666369__F8 IPA on CCl4-induced liver fibrosis PMC6596190__F1 APP can be cleaved through amyloidogenic or non-amyloidogenic pathways ENSG00000142192 PMC10778465__F1 The antitumor effect of SST receptors after ligand binding ENSG00000278195 ENSG00000132671 ENSG00000162009 ENSG00000291971 ENSG00000180616 ENSG00000157005 PMC5069779__F5 MIIP competing with Rac1-GTP to bind the PAK1-binding domain ENSG00000116691 ENSG00000149269 PMC6645632__F5 The hexosamine biosynthetic pathway (HBP) in the heart ENSG00000147162 ENSG00000198408 PMC6909129__F1 Pattern Recognition ReceptorsThe anti-adenoviral immune response is triggered by recognition of pathogen-associated molecular patterns (PAMPs) by PRRs ENSG00000150782 ENSG00000239732 ENSG00000164430 ENSG00000167207 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000276561 PMC7930745__F2 TMEM16A regulates EMT and cancer cell migration and metastasis ENSG00000168610 ENSG00000146648 PMC3887939__F1 Signaling mechanisms proposed for the mammalian autophagy pathway ENSG00000152348 ENSG00000198382 ENSG00000118640 ENSG00000057663 PMC3588000__F1 Biosynthesis of Phosphatidylethanolamine (PE) ENSG00000185813 ENSG00000173599 ENSG00000133027 PMC4278340__F1 Menin-mediated regulation of miRNA biogenesis uncovers the IRS2 pathway as a target for regulating pancreatic beta cells ENSG00000128191 ENSG00000113360 PMC9216458__F2 CD47–SIRPAlpha-targeted therapeutics: status and prospects ENSG00000112964 PMC4768069__F2 Bioinformatics analyses reveal changes in expression of genes associated with the Death Receptor Pathway ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000115317 ENSG00000026103 PMC6202673__F1 Proposed model of airway tolerance ENSG00000137033 ENSG00000137265 ENSG00000136869 ENSG00000166090 ENSG00000115009 PMC2581748__F2 Activation of the mammalian target of rapamycin (mTOR) pathway can result from numerous glioma-associated genetic changes ENSG00000198793 ENSG00000196712 PMC5472795__F8 Anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites ENSG00000012048 ENSG00000175054 ENSG00000163961 ENSG00000080345 ENSG00000134982 ENSG00000081377 ENSG00000162607 ENSG00000051180 ENSG00000112130 PMC1525002__F4 Sequence logo [41] of putative regulatory motif ENSG00000074800 PMC6434684__F1 Sonic Hedgehog Pathway ENSG00000164690 ENSG00000128602 PMC7764417__F2 Putative model for the development of (cardiac) lipid-induced insulin resistance ENSG00000135218 ENSG00000169047 PMC4972113__F1 Mechanisms of tumor responsiveness to statins ENSG00000115109 ENSG00000113161 ENSG00000165527 PMC5810242__F10 The interrelationships among p-AMPK, p-mTOR, p-ULK1, autophagy and apoptosis ENSG00000177169 ENSG00000198793 ENSG00000171791 PMC3281571__F2 MTOR pathway ENSG00000100811 ENSG00000177169 ENSG00000198793 ENSG00000169047 ENSG00000155792 ENSG00000167658 ENSG00000164327 ENSG00000167965 ENSG00000103257 ENSG00000168003 ENSG00000106070 ENSG00000118515 ENSG00000179632 ENSG00000140464 PMC2768039__F2 Genetic Basis for Kidney Cancer ENSG00000134086 ENSG00000100387 ENSG00000163235 PMC3281571__F1 Simplified view of the mTOR pathway ENSG00000169047 ENSG00000198793 ENSG00000167965 PMC3341446__F1 Illustration of the PI3K pathway signaling pathway PMC3335670__F3 Action of the enteropathogenic yersiniae Ysc T3SS effectors (Yops) on host cell signaling and survival ENSG00000070831 ENSG00000291971 ENSG00000136869 PMC12158951__F1 Two main mechanisms of Fn promoting CRC proliferation ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000172936 ENSG00000136869 PMC7289953__F1 Mechanisms underlying experimental liver transplant tolerance ENSG00000178860 ENSG00000136869 PMC8601819__F3 Naringenin: A Promising Therapeutic Agent against Organ Fibrosis ENSG00000150782 ENSG00000163914 ENSG00000168036 PMC5409051__F5 Social defeat stress causes depression-like behavior with metabolite changes in the prefrontal cortex of rats ENSG00000101280 ENSG00000027644 ENSG00000132478 ENSG00000134780 ENSG00000105499 ENSG00000147588 ENSG00000102977 ENSG00000281500 PMC6562953__F1 RKIP protein as a signaling modulator in lung cancer ENSG00000186575 ENSG00000164690 ENSG00000168610 PMC8591231__F5 Review on the molecular basis underlying the protective effects of Andrographis paniculata and andrographolide against myocardial injury ENSG00000002330 ENSG00000169047 ENSG00000168040 ENSG00000140443 ENSG00000026103 PMC2871498__F9 Working model for S1P/SK/S1PR interplay during acrosomal exocytosis ENSG00000157933 ENSG00000103222 ENSG00000183018 PMC3071501__F10 Genes mapping to KEGG pathway for hedgehog signaling ENSG00000112210 ENSG00000128602 PMC10586346__F3 Osteogenic differentiation-related signal pathway diagram ENSG00000130234 ENSG00000168036 ENSG00000152591 PMC6332930__F2 Interferon (IFN)-dependent IFN stimulated gene (ISG) transcription through the Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling ENSG00000159128 ENSG00000105397 ENSG00000115415 ENSG00000140968 ENSG00000185436 ENSG00000027697 ENSG00000168310 ENSG00000276561 ENSG00000142166 PMC5817353__F1 Subcellular compartmentalization of the Fe-S cluster and Moco assembly processes ENSG00000005194 ENSG00000178096 ENSG00000165898 ENSG00000155229 ENSG00000124217 ENSG00000164172 ENSG00000124615 ENSG00000139531 ENSG00000158125 ENSG00000135070 ENSG00000267673 ENSG00000144021 ENSG00000137714 ENSG00000136003 ENSG00000169627 PMC3289598__F1 Molecular Mechanisms of Drug Resistance in Natural Leishmania Populations Vary with Genetic Background ENSG00000062485 PMC6600680__F7 Mitochondria-mediated apoptotic signaling pathway by JNK and p38 ENSG00000132906 ENSG00000002330 ENSG00000164305 ENSG00000115317 PMC8212062__F7 Melatonin in Goat Hair Follicle Stem Cell Proliferation and Pluripotency Through Regulating the Wnt Signaling Pathway ENSG00000174059 PMC3283059__F2 Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway displaying transcripts in mitogen-activated protein kinase (MAPK) signaling pathway ENSG00000104626 ENSG00000172680 ENSG00000177606 ENSG00000130159 ENSG00000146648 ENSG00000081189 ENSG00000196712 ENSG00000026103 PMC3283059__F4 Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway display transcripts in cell cycle pathway ENSG00000145604 ENSG00000094804 ENSG00000134982 ENSG00000132646 ENSG00000164754 ENSG00000205250 ENSG00000117399 ENSG00000276876 PMC3428242__F1 Simplified schematic representation of the mammalian target of rapamycin (mTOR) signaling pathway.Notes: Red, pathway inhibitor; Green, pathway activator; Blue, mTOR complex protein.Abbreviation: NOS, not otherwise specified ENSG00000198793 ENSG00000163914 ENSG00000164327 ENSG00000167965 PMC9002269__F1 Fine-Tuning Cold Stress Response Through Regulated Cellular Abundance and Mechanistic Actions of Transcription Factors ENSG00000171735 ENSG00000108509 PMC8102909__F7 Disruption of the cholinergic anti-inflammatory response by R5-tropic HIV-1 protein gp120JRFL ENSG00000150782 ENSG00000171540 ENSG00000121966 PMC8346999__F10 Signaling Pathways Regulated by UBR Box-Containing E3 Ligases ENSG00000179331 ENSG00000127481 ENSG00000104517 ENSG00000125538 ENSG00000159459 ENSG00000091592 PMC9488848__F2 Use of multitarget tyrosine kinase inhibitors to attenuate platelet-derived growth factor signalling in lung disease ENSG00000198793 PMC2063819__F7 The newly identified NT3-activated signaling pathway ENSG00000121058 ENSG00000165527 ENSG00000161835 PMC5971440__F15 Arteriosclerotic G3BP1/RIG-I signaling in aortic VSM, a working model ENSG00000088888 ENSG00000281324 ENSG00000070831 ENSG00000285485 PMC11394960__F8 Contribution of miRs/target genes involved in the innate immune and inflammatory response pathway in the lungs in Lagovirus europaeus infection ENSG00000162711 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC11394960__F7 Contribution of miRs/target genes involved in the innate immune and inflammatory response pathway in the liver in Lagovirus europaeus infection ENSG00000162711 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC11843905__F14 STRING network of FREM2 ENSG00000175893 ENSG00000143341 ENSG00000166477 ENSG00000168743 ENSG00000138798 ENSG00000172009 ENSG00000150093 ENSG00000170454 ENSG00000155974 ENSG00000196581 ENSG00000107959 ENSG00000181499 ENSG00000173093 ENSG00000196236 ENSG00000188732 ENSG00000188176 ENSG00000115457 ENSG00000123213 ENSG00000198759 ENSG00000137203 ENSG00000138162 ENSG00000162374 ENSG00000118257 ENSG00000148357 ENSG00000169021 ENSG00000065361 ENSG00000162600 ENSG00000149557 ENSG00000086015 ENSG00000139880 ENSG00000150893 ENSG00000133107 ENSG00000164946 ENSG00000134809 ENSG00000178568 PMC11394960__F9 Contribution of miRs/target genes involved in the innate immune and inflammatory response pathway in the kidney in Lagovirus europaeus infection ENSG00000162711 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC5850959__F7A Transcriptomic data shows immunometabolic effects of vitamin D ENSG00000133895 ENSG00000039537 ENSG00000105329 ENSG00000170027 ENSG00000134982 ENSG00000134308 ENSG00000196591 ENSG00000205250 ENSG00000118971 ENSG00000134480 ENSG00000180210 ENSG00000149311 ENSG00000175054 ENSG00000171720 ENSG00000213658 ENSG00000147099 ENSG00000134057 ENSG00000143761 ENSG00000061273 ENSG00000105810 ENSG00000253729 PMC8346999__F11 Signaling Pathways Regulated by UBR Box-Containing E3 Ligases ENSG00000175054 ENSG00000132646 ENSG00000143751 ENSG00000159459 ENSG00000070950 PMC7589192__F2 Common signaling pathways of epithelial-to-mesenchymal transition based on Albrecht et al ENSG00000163914 ENSG00000084774 PMC11034122__F7 Different pathways activated in A ENSG00000197713 ENSG00000167508 ENSG00000047597 PMC11034122__F6 Comparative physiological, biochemical, metabolomic, and transcriptomic analyses reveal the formation mechanism of heartwood for Acacia melanoxylon ENSG00000171759 ENSG00000084774 PMC6052114__F7 Models of SLC9C1 gating by voltage and cAMP ENSG00000285044 ENSG00000145321 ENSG00000063180 PMC5864870__F1 Anti-gliomagenic effects of different psychiatric and non-psychiatric drugs as demonstrated via in vitro studies ENSG00000198793 ENSG00000177606 ENSG00000170430 ENSG00000171791 ENSG00000166851 ENSG00000146648 PMC5372812__F1 Schematic representation of the general phenylpropanoid pathway leading to major branches of flavonoid biosynthesis and their possible interaction with miRNAs ENSG00000110921 ENSG00000151151 PMC4546649__F6 Genetic and Informatic Analyses Implicate Kif12 as a Candidate Gene within the Mpkd2 Locus That Modulates Renal Cystic Disease Severity in the Cys1cpk Mouse ENSG00000008710 ENSG00000170927 ENSG00000205795 ENSG00000136883 PMC7492232__F1 Proposed mechanisms of sex-related susceptibility to COVID-19 ENSG00000130234 ENSG00000184012 PMC8526435__F2 Repositioning Ivermectin for Covid-19 treatment: Molecular mechanisms of action against SARS-CoV-2 replication ENSG00000105397 ENSG00000115415 ENSG00000291971 ENSG00000130234 ENSG00000138798 ENSG00000033800 ENSG00000168610 ENSG00000146648 PMC4833573__F2 Pediatric Gliomas as Neurodevelopmental Disorders ENSG00000157764 ENSG00000198793 ENSG00000077782 ENSG00000196712 ENSG00000179295 PMC12135226__F2 Lactylation ENSG00000137804 ENSG00000149658 ENSG00000189403 PMC5730868__F1 Self-renewal pathways in CSCs (A) Wnt signaling pathway, (B) SONIC Hedgehog signaling pathway, and (C) Notch signaling pathway ENSG00000117425 ENSG00000134982 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC3176054__F5 Proposed model of early pathologic events occurring in the lacrimal glands of C57BL/6.NOD-Aec1Aec2 male mice defined by changes in gene expression ENSG00000291971 ENSG00000046604 PMC2839454__F2 Too Old to Fight? Aging and its Toll on Innate Immunity ENSG00000174125 ENSG00000170458 PMC11773722__F9 Graphical summary of disrupted immune and structural milieu in the intestinal epithelium of Mpj and Lpr mice ENSG00000157404 PMC8056044__F6 Illustration of neuronal and astrocytic pathways implicated in the disease according to the top scoring genes according to our integrated ranking ENSG00000142192 ENSG00000171720 ENSG00000160087 ENSG00000196935 ENSG00000130175 ENSG00000108518 ENSG00000107223 PMC3209350__F1 Synthesis, utilization, and regeneration of glutathione and regulation of mTORC1 activity PMC7196551__F1 Natural products targeting different cell signaling pathway ENSG00000107485 ENSG00000001626 ENSG00000047936 ENSG00000146648 PMC3966314__F3 Impact of miR-215 on cell proliferation, cell cycle, chemoresistance and EMT ENSG00000228716 ENSG00000169554 ENSG00000143476 ENSG00000112118 PMC3436147__F8 Putative mechanisms of the effect of the Kv1 ENSG00000177272 ENSG00000291603 ENSG00000213658 ENSG00000197971 ENSG00000126353 ENSG00000049768 PMC3258214__F1 Bcl-3 signaling cascade ENSG00000083799 ENSG00000168610 PMC2916958__F7 Proposed model for the role of NOX4 and DUOX2 in promoting cell cycle entry ENSG00000140279 ENSG00000135446 ENSG00000086991 PMC4601608__F4 Schematic drawing summarizing the physiological regulation of the melanocortin pathway and pathological findings in the in Ankrd26−/− mice ENSG00000198576 ENSG00000115138 ENSG00000166603 ENSG00000168610 PMC8440041__F2 Mucus targeting as a plausible approach to improve lung function in COVID-19 patients ENSG00000146648 ENSG00000293532 ENSG00000106546 ENSG00000080298 PMC8277948__F10 Tumor-Derived Extracellular Vesicles Promote Activation of Carcinoma-Associated Fibroblasts and Facilitate Invasion and Metastasis of Ovarian Cancer by Carrying miR-630 ENSG00000078098 PMC3840254__F8 Summary of proposed pathway leading from TGFB1 receptor binding to ROS generation ENSG00000198793 ENSG00000086991 ENSG00000047936 ENSG00000175567 ENSG00000096717 PMC9455275__F5 Identify metabolism-related genes IDO1, ALDH2, NCOA2, SLC7A5, SLC3A2, LDHB, and HPRT1 as potential prognostic markers and correlate with immune infiltrates in head and neck squamous cell carcinoma ENSG00000101751 ENSG00000122966 ENSG00000179091 ENSG00000111837 ENSG00000136997 PMC9085840__F2 Pathways of mitophagy ENSG00000123240 ENSG00000104946 PMC5239781__F1 Complement activation ENSG00000039537 ENSG00000291559 ENSG00000196352 ENSG00000117335 ENSG00000166278 ENSG00000236625 PMC4081624__F1 IGF signaling pathway ENSG00000197081 ENSG00000291972 ENSG00000112964 ENSG00000157005 ENSG00000140443 PMC12190578__F2 Simplified schematic of PpIX synthesis in heme biosynthetic pathway ENSG00000080819 ENSG00000115657 ENSG00000118777 PMC7003708__F1 Mass spectrometry–based proteomics of mdx fibro/adipogenic progenitors (FAPs) reveals a significant alteration of key metabolic pathways ENSG00000169710 ENSG00000163541 ENSG00000131143 ENSG00000127884 ENSG00000157184 ENSG00000139180 ENSG00000110717 ENSG00000146701 ENSG00000075239 ENSG00000062485 ENSG00000160194 ENSG00000197713 ENSG00000067057 ENSG00000108515 ENSG00000101365 ENSG00000165264 ENSG00000178127 ENSG00000267855 ENSG00000065518 ENSG00000151366 ENSG00000172005 ENSG00000189043 ENSG00000184076 ENSG00000115361 ENSG00000110435 ENSG00000164708 ENSG00000131495 ENSG00000073578 ENSG00000100288 ENSG00000095321 ENSG00000117118 ENSG00000074800 ENSG00000128609 ENSG00000100412 ENSG00000091140 ENSG00000131473 ENSG00000112695 ENSG00000184983 ENSG00000138029 ENSG00000178741 ENSG00000153574 ENSG00000105953 ENSG00000172340 ENSG00000131828 ENSG00000143252 ENSG00000099795 ENSG00000119013 ENSG00000122971 ENSG00000159399 PMC5547213__F1 Crosstalk and Interplay between the Ubiquitin-Proteasome System and Autophagy ENSG00000177169 ENSG00000110497 ENSG00000128272 PMC2878012__F5 Model for the role of SQSTM1 in regulating the integrity of the Keap1-Nrf2 cell defense pathway ENSG00000284099 ENSG00000079999 PMC5373463__F1 Regulatory networks that control intrarenal RAS activity ENSG00000118972 ENSG00000168036 PMC9577257__F2 WNT signaling at the intersection between neurogenesis and brain tumorigenesis ENSG00000070831 ENSG00000100592 ENSG00000134982 ENSG00000163914 ENSG00000168036 ENSG00000146122 PMC10417677__F3 Anti-inflammatory mechanism of MBPs ENSG00000162711 PMC8876822__F3 Non-Canonical Host Intracellular Niche Links to New Antimicrobial Resistance Mechanism ENSG00000110799 ENSG00000137845 ENSG00000146648 PMC3412259__F1 This diagram of BCR/CD19-initiated signaling shows two key outcomes of PI3K activation ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000198793 ENSG00000164327 ENSG00000010671 PMC5873983__F1 Serum homocysteine, arsenic methylation, and arsenic-induced skin lesion incidence in Bangladesh: a one-carbon metabolism candidate gene study ENSG00000214435 ENSG00000100714 ENSG00000173638 ENSG00000124275 ENSG00000185339 ENSG00000110195 ENSG00000076351 ENSG00000116984 PMC4360475__F6 Bisphenol-A Affects Male Fertility via Fertility-related Proteins in Spermatozoa ENSG00000165119 ENSG00000117118 ENSG00000138798 ENSG00000167468 ENSG00000185591 ENSG00000126432 PMC7781331__F2 WormPaths examples ENSG00000083857 ENSG00000104899 ENSG00000165323 ENSG00000124253 ENSG00000131828 ENSG00000129744 PMC2839169__F1 Simplified illustration of the epidermal growth factor receptor (EGFR) pathway with the RAS/MAPK and PIK3CA/PTEN cascades ENSG00000198793 ENSG00000146648 PMC8989677__F8 Cartoon of mode of action of BNT162b2 in vivo ENSG00000111537 ENSG00000145321 ENSG00000285379 ENSG00000142166 PMC4861419__F6 Schematic illustration represents the potential signaling transduction mechanism by which cancer cell-derived exosomes prevent monocyte apoptosis ENSG00000064012 ENSG00000164305 PMC6949840__F3 (1) TNFA, and IL-1B can induce the expression of TGFB PMC3921549__F1 Carcinogenetic pathway and classification of colorectal cancer ENSG00000157764 ENSG00000134982 PMC8511458__F2 Interplay Between Non-Canonical NFKB Signaling and Hepatitis B Virus Infection ENSG00000104856 ENSG00000179750 ENSG00000111321 ENSG00000131323 PMC11311387__F4 Involvement of p53 in cell stress responses and glycosylation-related pathways and the relationship between p53 glycosylation and cancer progression ENSG00000187097 ENSG00000078237 ENSG00000179163 PMC12058482__F3 Molecular mechanisms of epithelial-mesenchymal transition ENSG00000138798 ENSG00000170558 ENSG00000108821 PMC12058482__F1 Interaction between inflammatory response and alveolar epithelial cell injury ENSG00000162711 ENSG00000137033 ENSG00000168610 PMC3875243__F1 Characterization of Negative Feedback Network Motifs in the TGFB Signaling Pathway ENSG00000090402 ENSG00000122966 ENSG00000166278 ENSG00000174611 PMC6712945__F5 Schemes for nanoparticles loaded with specific agents to target TAM signaling pathways ENSG00000214285 ENSG00000121807 PMC7577085__F2 Signaling pathways activated by MSP and RON ENSG00000162711 ENSG00000136869 ENSG00000175104 ENSG00000182606 PMC7487068__F7 Impairment of the autophagy-lysosomal pathway and activation of pyroptosis in macular corneal dystrophy ENSG00000162711 ENSG00000125538 ENSG00000183196 PMC8627910__F2 Fragment of the gene network, containing genes associated with PIN1 and genes related to the auxin signaling pathway ENSG00000127445 ENSG00000122218 PMC7140485__F1 Canonical and non-canonical pro-fibrotic pathways of transforming growth factor B (TGFB) and Wnt and the pro-fibrotic interleukin 11 (IL-11) pathway PMC2342468__F1 Cardiac contraction, relaxation and rate by the endothelial nitric oxide synthase (eNOS): lessons from genetically modified mice ENSG00000041982 ENSG00000198626 PMC3101043__F2 Endogenous and exogenous regulators of TLR activation ENSG00000183735 ENSG00000172936 ENSG00000150455 ENSG00000175104 PMC6125217__F1 Nodal and Shh Signaling ENSG00000064309 ENSG00000180447 ENSG00000160973 ENSG00000106571 ENSG00000144857 ENSG00000241186 ENSG00000156574 ENSG00000154309 ENSG00000164690 ENSG00000128602 PMC3985001__F1 The CNS-immune system crosstalk ENSG00000146469 PMC9103744__F6 Overexpression of Renin-B Induces Warburg-like Effects That Are Associated with Increased AKT/mTOR Signaling ENSG00000142192 ENSG00000090857 ENSG00000164327 PMC8844185__F3 Future Directions in Diagnosis, Prognosis and Disease Monitoring of Adrenocortical Carcinoma: Novel Non-Invasive Biomarkers ENSG00000179142 PMC4450221__F2 Mechanisms underlying the developmental programming of NAFLD ENSG00000125538 ENSG00000169710 ENSG00000136869 PMC8733707__F7 ENO3 Inhibits Growth and Metastasis of Hepatocellular Carcinoma via Wnt/Beta-Catenin Signaling Pathway ENSG00000087245 ENSG00000137673 ENSG00000108515 ENSG00000168036 ENSG00000100985 PMC12058482__F4 Severe acute respiratory syndrome coronavirus 2 infections and epithelial-mesenchymal transition ENSG00000291971 ENSG00000130234 ENSG00000184012 ENSG00000136869 ENSG00000168610 PMC5187527__F4 Mechanism of estradiol-dependent repression of GD3S in ER-positive breast cancer cells ENSG00000111728 PMC2915454__F4 Pathways underlying absorption of cholesterol from the intestinal lumen and its delivery to the liver ENSG00000138075 ENSG00000138823 ENSG00000015520 ENSG00000120437 ENSG00000143921 PMC11977258__F4 OB-EC communication ENSG00000152266 ENSG00000105329 ENSG00000110799 PMC8938281__F10 MiR-23b/27b/24-1 Cluster Inhibits Hepatic Fibrosis by Inactivating Hepatic Stellate Cells ENSG00000170365 ENSG00000137834 ENSG00000164171 PMC4196276__F5 Entourage: Visualizing Relationships between Biological Pathways using Contextual Subsets ENSG00000169291 ENSG00000129946 ENSG00000138798 PMC1783813__F3 Physiology and immunology of the cholinergic antiinflammatory pathway ENSG00000170458 ENSG00000189403 ENSG00000136869 PMC7907897__F2 NRF2 regulatory mechanisms.A) three reported negative regulatory mechanisms of NRF2 ENSG00000254986 ENSG00000148400 ENSG00000103222 ENSG00000176153 ENSG00000118777 ENSG00000023909 ENSG00000057663 ENSG00000106546 ENSG00000139618 ENSG00000187134 ENSG00000079999 ENSG00000012048 ENSG00000114770 ENSG00000178573 ENSG00000167468 ENSG00000161533 ENSG00000167996 ENSG00000051180 ENSG00000163898 ENSG00000100219 ENSG00000023839 PMC6213406__F1 Putative anticancer effects of MTF exemplified by molecular and cellular key events ENSG00000198793 ENSG00000168610 ENSG00000151151 PMC8557262__F1 Possible harm from glucocorticoid drugs misuse in the early phase of SARS-CoV-2 infection: a narrative review of the evidence ENSG00000130234 ENSG00000145321 PMC2710522__F1 Logic of EGFR/ErbB Signaling: Theoretical Properties and Analysis of High-Throughput Data ENSG00000002330 ENSG00000065361 ENSG00000138798 ENSG00000198793 ENSG00000115904 ENSG00000168610 ENSG00000169752 ENSG00000106683 ENSG00000115415 ENSG00000163235 ENSG00000149269 ENSG00000160293 ENSG00000178568 ENSG00000282895 PMC5396097__F3 Autophagy-mediated regulation of macrophages and its applications for cancer ENSG00000108691 ENSG00000198793 ENSG00000136869 ENSG00000121807 PMC5396097__F1 Autophagy-mediated regulation of macrophages and its applications for cancer ENSG00000124102 ENSG00000177169 ENSG00000110497 ENSG00000097033 ENSG00000198382 ENSG00000126775 ENSG00000196455 ENSG00000198793 PMC2002564__F1 Arterial–venous specification in the developing embryo ENSG00000196411 ENSG00000164690 ENSG00000178919 PMC7106955__F1 Main mechanisms of ferroptosis ENSG00000168003 ENSG00000196839 ENSG00000167468 ENSG00000072274 PMC3406705__F8 Hypothetical model elucidating the regulation of phosphorylated FAK expression through an integrin A5 and B1-mediated MEK-ERK1/2-dependent pathway after ESWT ENSG00000150093 ENSG00000168036 PMC11882760__F3 DUBs on periodontal inflammation and bone resorption ENSG00000162711 ENSG00000150782 ENSG00000152484 ENSG00000101310 ENSG00000165312 ENSG00000010278 ENSG00000083799 ENSG00000175104 ENSG00000168610 ENSG00000076604 PMC8396359__F4 Duality of Caspases in Cancer, as Told through the Fly ENSG00000149311 ENSG00000175054 ENSG00000138385 PMC4586293__F2 Neurohormetic Phytochemicals: An Evolutionary - Bioenergetic Perspective ENSG00000198793 ENSG00000096717 PMC5428057__F6 Schematic overview summarizing the functional significance and regulation of COX-2 in PDAC ENSG00000138798 ENSG00000185591 ENSG00000146648 PMC5745276__F1 Wnt pathway can be classified as canonical and non-canonical ENSG00000229894 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC3117391__F3 Pathway for getifinib and docetaxel to generate the synergistic effects on KRT8 ENSG00000127445 ENSG00000291971 ENSG00000177606 ENSG00000115904 ENSG00000171791 ENSG00000140299 ENSG00000168610 ENSG00000146648 ENSG00000164305 ENSG00000133818 PMC5789355__F1 Signal transduction through the mTOR complexes ENSG00000198793 ENSG00000118515 ENSG00000155792 ENSG00000168610 ENSG00000084774 PMC6879499__F3 Construction of pathway map and PPI interaction map ENSG00000004975 ENSG00000143799 ENSG00000140992 ENSG00000105835 ENSG00000122420 ENSG00000169047 ENSG00000023287 ENSG00000198793 ENSG00000155792 ENSG00000110931 ENSG00000164327 ENSG00000167965 ENSG00000141564 ENSG00000077463 ENSG00000121879 ENSG00000089159 ENSG00000157240 ENSG00000109819 ENSG00000143320 ENSG00000266173 ENSG00000160951 ENSG00000140464 ENSG00000196712 ENSG00000177169 ENSG00000168209 ENSG00000171105 ENSG00000119487 ENSG00000005339 ENSG00000157764 ENSG00000100906 ENSG00000284161 ENSG00000198626 ENSG00000281877 ENSG00000182621 ENSG00000105568 ENSG00000161960 ENSG00000187840 ENSG00000132170 ENSG00000079999 ENSG00000204673 ENSG00000134324 ENSG00000096717 ENSG00000186654 ENSG00000227345 PMC5745276__F3 Cross-Talk between the Wnt, Notch and Sonic Hedgehog Pathways- Beta-catenin can drive activation of Notch signaling by increasing expression of the JAG1 gene, which encodes the Notch ligand Jagged1 ENSG00000229894 ENSG00000168036 ENSG00000164690 ENSG00000104332 ENSG00000128602 PMC7106955__F3 Hippo signalling pathway ENSG00000186575 ENSG00000072274 ENSG00000086991 ENSG00000084774 ENSG00000134531 PMC8820687__F1 Brain as a source and a target of prolactin in mammals ENSG00000291971 ENSG00000113494 PMC3645678__F3 Involvement of Cdc42, Rac1 and RhoA in vesicle trafficking, cellular transformation, invadopodia formation and metastasis ENSG00000070831 ENSG00000163914 PMC8108463__F3 Endogenous retroviruses in the origins and treatment of cancer ENSG00000088888 ENSG00000276561 ENSG00000164342 PMC9251540__F1 SFRP1 Negatively Modulates Pyroptosis of Fibroblast‐Like Synoviocytes in Rheumatoid Arthritis: A Review ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000104332 PMC9251540__F3 SFRP1 Negatively Modulates Pyroptosis of Fibroblast‐Like Synoviocytes in Rheumatoid Arthritis: A Review ENSG00000278718 ENSG00000162711 ENSG00000137757 ENSG00000125538 ENSG00000196954 ENSG00000132341 PMC9251540__F2 SFRP1 Negatively Modulates Pyroptosis of Fibroblast‐Like Synoviocytes in Rheumatoid Arthritis: A Review ENSG00000135547 ENSG00000148400 ENSG00000074181 ENSG00000273529 ENSG00000114315 PMC8885627__F1 Macrophages and Metabolic Reprograming in the Tumor Microenvironment ENSG00000107562 ENSG00000169429 PMC9579717__F6 Chloride intracellular channel 1 promotes esophageal squamous cell carcinoma proliferation via mTOR signalling ENSG00000155792 ENSG00000167965 PMC3146245__F2 Genetic model for nuage assembly and piRNA pathway genes in mice ENSG00000095627 ENSG00000143194 ENSG00000180113 ENSG00000073146 ENSG00000196116 PMC5741148__F1 Regulation of the FoxO1/3 activity by phosphorylation ENSG00000117525 ENSG00000150907 ENSG00000169047 ENSG00000133124 PMC6349168__F1 Molecular interactions in Immunometabolism governing lipid metabolic disorders ENSG00000135218 ENSG00000132478 ENSG00000168610 PMC125566__F7 Negative regulation of the Wnt–Beta-catenin pathway by the transcriptional repressor HBP1 ENSG00000134982 ENSG00000168036 PMC6400832__F1 The nutritional sensing O-GlcNAcylation ENSG00000147162 ENSG00000198408 ENSG00000013375 PMC4998060__F2 Signaling network that regulates ISC activity in response to injury ENSG00000146648 PMC2206598__F4 Regulatory networks sensitive to tyrosine kinase inhibitors in H3255 and MKN45 cells revealed by PhosphpScan-SILAC study ENSG00000142627 ENSG00000143839 ENSG00000146648 ENSG00000132341 PMC4571978__F1 A, diagram of the workflow of mitochondrial proteomic studies ENSG00000151657 ENSG00000141086 ENSG00000084774 PMC2075270__F1 Exercise improves phosphatidylinositol-3,4,5-trisphosphate responsiveness of atypical protein kinase C and interacts with insulin signalling to peptide elongation in human skeletal muscle ENSG00000124102 ENSG00000169047 ENSG00000198793 ENSG00000284161 ENSG00000167658 PMC4038907__F4 Progesterone and breast cancer ENSG00000138798 ENSG00000123374 ENSG00000185591 PMC4143405__F5 Key tumor suppressor genes inactivated by “greater promoter” methylation and somatic mutations in head and neck cancer ENSG00000151376 ENSG00000148400 ENSG00000150907 ENSG00000137265 ENSG00000196092 ENSG00000100219 ENSG00000164690 ENSG00000114315 ENSG00000118971 ENSG00000125813 PMC8222665__F3 Tumor-Associated Macrophages: A Potential Target for Cancer Therapy ENSG00000108691 ENSG00000081041 ENSG00000107562 ENSG00000198053 ENSG00000121807 ENSG00000121966 PMC6293973__F1 The Receptor for Advanced Glycation Endproducts (RAGE) and Mediation of Inflammatory Neurodegeneration ENSG00000189403 PMC5974440__F2 Regulation of stemness in the intestinal stem-cell niche ENSG00000162337 ENSG00000138798 ENSG00000168036 ENSG00000146648 PMC9691389__F6 Integrated Analysis of mRNA and lncRNA Expression Profiles Reveals Regulatory Networks Associated with Decompensated Cirrhosis ENSG00000166340 ENSG00000157077 ENSG00000285302 ENSG00000129226 ENSG00000102575 ENSG00000143226 ENSG00000165527 ENSG00000169231 ENSG00000168118 ENSG00000072134 ENSG00000196961 ENSG00000130164 ENSG00000224320 ENSG00000072694 ENSG00000078053 ENSG00000034713 ENSG00000183020 ENSG00000110911 ENSG00000162747 ENSG00000178568 ENSG00000131400 PMC5966388__F6 Dysregulation of the MiR-449b target TGFBI alters the TGFB pathway to induce cisplatin resistance in nasopharyngeal carcinoma ENSG00000170558 PMC8586445__F1 T-Cell Metabolism in Graft Versus Host Disease ENSG00000168003 ENSG00000198793 ENSG00000159399 ENSG00000026103 PMC7492601__F7 Biological mechanism of lncRNA C1RL-AS1 in GC ENSG00000168036 PMC11054595__F2 Mechanisms or pathways associated with sepsis-induced ALI ENSG00000172936 ENSG00000136869 PMC5431011__F7 Glycerophospholipid metabolism is induced in parasitized A ENSG00000163624 ENSG00000042832 ENSG00000087157 ENSG00000188784 ENSG00000173599 ENSG00000160216 ENSG00000062485 ENSG00000123684 PMC10380468__F2 Investigation of the Effects of Metallic Nanoparticles on Fertility Outcomes and Endocrine Modification of the Hypothalamic-Pituitary-Gonadal Axis ENSG00000109163 ENSG00000113070 ENSG00000146648 PMC4115674__F1 Ras/MAPK signal transduction pathway ENSG00000157764 ENSG00000110395 ENSG00000115904 ENSG00000166068 ENSG00000108061 ENSG00000196712 ENSG00000062485 PMC6747293__F1 Stress-induced senescence ENSG00000149311 ENSG00000175054 ENSG00000135446 ENSG00000123374 ENSG00000100526 ENSG00000105810 PMC111167__F1 BR biosynthesis pathway ENSG00000108582 ENSG00000062485 PMC3193406__F3 NIK stabilization as a mechanism of non-canonical NFKB signaling ENSG00000186660 ENSG00000131323 ENSG00000127191 PMC3193406__F2 Positive and negative domains regulating p100 processing ENSG00000100387 ENSG00000113558 ENSG00000162924 PMC3193406__F1 Canonical and non-canonical NFKB signaling pathways ENSG00000104856 ENSG00000186716 ENSG00000173039 ENSG00000111321 PMC5136497__F3 Involvement of cellular miRNAs in the signaling pathway of the immune response in sepsis ENSG00000115008 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000125347 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC12151073__F2 Mechanisms by which lactate modulates the innate immune responses ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC4594188__F1C Significant signaling pathway networks in each group ENSG00000285176 ENSG00000067066 ENSG00000136997 ENSG00000162924 ENSG00000164093 PMC5817863__F1 Schematic view of the circadian pathway ENSG00000111602 ENSG00000179094 ENSG00000069667 PMC4594188__F1E Significant signaling pathway networks in each group ENSG00000166862 PMC4594188__F1A Significant signaling pathway networks in each group ENSG00000136997 ENSG00000185591 ENSG00000115718 PMC9597979__F7 Transcriptional regulation mechanism of wheat varieties with different nitrogen use efficiencies in response to nitrogen deficiency stress ENSG00000221818 PMC5441174__F7 Schematic diagram of the FOXM1/Beta-Catenin complex in human osteosarcoma cells ENSG00000168036 ENSG00000196628 PMC5056611__F1 SETD1A-induced miRNAs suppress gene expression modules ENSG00000159388 ENSG00000099381 PMC5514447__F2 Low-dose triptolide and aspirin suppress NFKB survival pathways ENSG00000019991 ENSG00000157404 ENSG00000135218 ENSG00000161798 ENSG00000058085 ENSG00000139567 ENSG00000164251 ENSG00000148926 ENSG00000276644 ENSG00000182985 ENSG00000103241 ENSG00000131477 ENSG00000166147 ENSG00000106546 ENSG00000053747 ENSG00000049130 ENSG00000157510 ENSG00000115457 ENSG00000064989 ENSG00000128917 ENSG00000163825 ENSG00000156298 ENSG00000083444 ENSG00000125538 ENSG00000154721 ENSG00000185591 ENSG00000125810 ENSG00000128342 ENSG00000125266 ENSG00000149564 ENSG00000115008 ENSG00000112964 ENSG00000197635 ENSG00000124766 ENSG00000106511 ENSG00000164171 ENSG00000164120 ENSG00000135245 ENSG00000089225 ENSG00000111145 ENSG00000075223 ENSG00000117122 ENSG00000133110 ENSG00000163032 ENSG00000156427 ENSG00000136160 ENSG00000134531 PMC6221181__F1 Glucocorticoids regulate NK cells and ILC1s functions upon MCMV infection ENSG00000111537 ENSG00000157514 ENSG00000158106 PMC9010746__F1 Controlling neural territory patterning from pluripotency using a systems developmental biology approach ENSG00000170365 ENSG00000156574 ENSG00000184916 PMC4862604__F4 Repair Pathway Choices and Consequences at the Double-Strand Break ENSG00000012048 ENSG00000083093 ENSG00000051180 ENSG00000177084 ENSG00000106546 ENSG00000139618 PMC3295626__F1 JAK-STAT intracellular signaling pathway in myelofibrosis ENSG00000198793 PMC4862604__F3 Repair Pathway Choices and Consequences at the Double-Strand Break ENSG00000012048 ENSG00000083093 ENSG00000187790 ENSG00000197299 ENSG00000051180 ENSG00000177084 ENSG00000139618 PMC9097270__F6 DNA repair, recombination, and damage signaling ENSG00000178295 ENSG00000057468 ENSG00000285246 ENSG00000051180 ENSG00000120868 ENSG00000171791 PMC7730291__F1 Wnt–FAK signaling crosstalks and inhibitors ENSG00000281324 ENSG00000162337 ENSG00000291971 ENSG00000134982 ENSG00000102312 PMC4862604__F2 Repair Pathway Choices and Consequences at the Double-Strand Break ENSG00000149311 ENSG00000012048 ENSG00000080345 PMC9066194__F4 Function and Regulation of SAPCD2 in Physiological and Oncogenic Processes ENSG00000168036 PMC8577250__F1 Low-intensity pulsed ultrasound stimulates proliferation of stem/progenitor cells: what we need to know to translate basic science research into clinical applications ENSG00000064666 ENSG00000134057 ENSG00000198793 ENSG00000136869 ENSG00000162924 ENSG00000145386 PMC6522871__F2 Small molecule inhibitors and the ALK-Smad signaling pathway PMC7033031__F9 TRPV4 Protects the Lung from Bacterial Pneumonia via MAPK Molecular Pathway Switching ENSG00000108691 ENSG00000163739 ENSG00000136869 PMC3723343__F3 Cripto/GRP78 modulation of the TGFB pathway in development and oncogenesis ENSG00000291971 ENSG00000241186 ENSG00000156574 PMC6466717__F2 Biosynthetic pathway of Plasmalogens ENSG00000197601 PMC11546748__F2 Molecular and hormonal pathways contributing to insulin resistance in gestational diabetes ENSG00000150782 ENSG00000108691 ENSG00000198793 PMC5706779__F3 Novel Mechanisms and Functions of Complement ENSG00000197713 ENSG00000168036 PMC9923233__F7 Screening for diagnostic targets in tuberculosis and study on its pathogenic mechanism based on mRNA sequencing technology and miRNA-mRNA-pathway regulatory network ENSG00000138798 ENSG00000109906 ENSG00000115806 ENSG00000288461 ENSG00000275066 ENSG00000292366 ENSG00000112290 ENSG00000143761 ENSG00000197959 ENSG00000055163 ENSG00000162607 ENSG00000163848 ENSG00000048028 ENSG00000145349 ENSG00000155657 PMC2814418__F8 VDR-dependent and auxiliary pathways that lead to deltanoid-induced monocytic differentiation of myeloid leukemia cells ENSG00000170458 PMC4851692__F4 Effects of C10 on gene expression ENSG00000067992 ENSG00000109390 PMC7137344__F1 Functional alterations and HSC aging mechanisms ENSG00000198793 ENSG00000265972 ENSG00000047936 PMC6771146__F6 String network of proteins (encoded by the differentially expressed genes (DEGs)) involved in signalling pathways ENSG00000157404 ENSG00000049130 ENSG00000100632 PMC6771146__F4 Co-expression analysis of genes overexpressed in Puławska pigs, characterized by high feed conversion values ENSG00000182718 ENSG00000197747 PMC11593353__F2 Differential Gene Expression Associated with Idiopathic Epilepsy in Belgian Shepherd Dogs ENSG00000213928 ENSG00000115415 PMC4384327__F3 APP protein-protein interaction networks ENSG00000142192 ENSG00000107562 ENSG00000160145 ENSG00000142798 ENSG00000197471 ENSG00000196839 ENSG00000171049 ENSG00000136854 ENSG00000189056 ENSG00000157193 ENSG00000087085 ENSG00000089041 ENSG00000064547 ENSG00000101680 ENSG00000275066 ENSG00000137642 ENSG00000161921 ENSG00000170458 ENSG00000108688 ENSG00000132535 PMC5630445__F3 The role of toll-like receptor 4 in tumor microenvironment ENSG00000170458 ENSG00000125538 ENSG00000136869 PMC7801279__F2 Drugs treat VaD through regulating inflammation-related signaling pathways ENSG00000162711 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000096717 PMC7842189__F2 Microglia-Tissue Consensus Module Microglia Disease Time Course and Pathway Annotation ENSG00000011600 ENSG00000187764 ENSG00000165527 ENSG00000158869 ENSG00000136807 ENSG00000239732 ENSG00000159216 ENSG00000172216 ENSG00000161847 ENSG00000023892 ENSG00000140464 ENSG00000130340 ENSG00000101160 ENSG00000148400 ENSG00000077984 ENSG00000108518 ENSG00000188389 ENSG00000136167 ENSG00000105397 ENSG00000170458 ENSG00000116584 ENSG00000070831 ENSG00000110651 ENSG00000186818 ENSG00000111348 ENSG00000077150 ENSG00000088888 ENSG00000109861 ENSG00000011422 ENSG00000006712 ENSG00000105246 ENSG00000126458 ENSG00000125637 ENSG00000174125 ENSG00000140678 ENSG00000162512 ENSG00000081237 ENSG00000023902 ENSG00000115267 ENSG00000273686 ENSG00000100060 ENSG00000166428 ENSG00000281614 ENSG00000011304 ENSG00000133112 ENSG00000134324 ENSG00000123143 ENSG00000100365 ENSG00000138760 ENSG00000136689 PMC4170139__F4 Late signaling events in de novo cytokine/chemokine production ENSG00000033327 ENSG00000213658 ENSG00000010810 ENSG00000198793 ENSG00000172005 ENSG00000172936 ENSG00000175104 PMC4085879__F2 Targets in T-ALL: PI3K/AKT/mTOR, cyclin D3:CDK4/6, BRD4/MYC ENSG00000141867 ENSG00000135446 ENSG00000198793 ENSG00000105810 PMC8690056__F1 Nicotinamide and acute kidney injury ENSG00000105835 ENSG00000278488 PMC11544004__F9 Impact of the environment on NK cells: Phytoncide model ENSG00000111537 ENSG00000129167 ENSG00000140465 ENSG00000106546 ENSG00000278693 PMC8021541__F7 LncRNA H19 regulates sensitivity to EGFR‐targeted therapy through different mechanisms ENSG00000291971 ENSG00000146648 PMC3944232__F7 Schematic illustration of LEF1/CYLD and cIAPs in the modulation of RIP1 deubiquitination and triggering of apoptosis via caspase-8 ENSG00000138795 ENSG00000083799 PMC11544004__F5 Dynamics of activation signaling in NK cells in contact with cancer and stressed cells ENSG00000291603 ENSG00000111981 ENSG00000291971 ENSG00000204463 ENSG00000134215 ENSG00000231179 ENSG00000141968 ENSG00000131015 ENSG00000131019 ENSG00000111537 ENSG00000110395 ENSG00000213658 ENSG00000117091 ENSG00000150907 ENSG00000204520 ENSG00000160293 PMC11955616__F4 Function and Regulatory Mechanisms of the RIG-I Signaling Pathway in Lung Cancer (By figdraw) ENSG00000183735 ENSG00000088888 ENSG00000276561 PMC8466094__F2 Crosstalk between Autophagy and Inflammatory Processes in Cancer ENSG00000198793 ENSG00000284099 ENSG00000172936 ENSG00000237693 PMC11955616__F3 Function and Regulatory Mechanisms of the TLR Signaling Pathway in Lung Cancer (By figdraw) ENSG00000174123 ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000276561 ENSG00000164342 PMC11955616__F2 The cGAS-STING Signaling Pathway in Lung Cancer Immunotherapy (By figdraw) ENSG00000183735 ENSG00000164430 ENSG00000158220 ENSG00000284764 PMC8021541__F2 LncRNAs sponge microRNAs and then regulate radiosensitivity through different signaling pathways ENSG00000253293 ENSG00000087245 ENSG00000170558 ENSG00000142453 ENSG00000100985 ENSG00000076770 ENSG00000146648 PMC5225216__F2 Hypothesis of intercellular energy relocation triggered by gut microbiota ENSG00000150455 PMC5225216__F1 Intracellular energy relocation in fat body cell of Drosophila and immune cell of human ENSG00000172936 ENSG00000150455 PMC4426903__F3 Evolutionary Changes in Promoter and Enhancer Activity During Human Corticogenesis ENSG00000137834 ENSG00000112837 ENSG00000138798 ENSG00000143842 ENSG00000156574 ENSG00000140092 ENSG00000087303 ENSG00000166147 ENSG00000116962 ENSG00000170365 ENSG00000176692 ENSG00000121068 ENSG00000292234 ENSG00000185591 ENSG00000108821 ENSG00000197467 ENSG00000146648 PMC7550584__F3 Schematic pathway for DEP-mediated olfactory dysfunction ENSG00000003137 ENSG00000163630 ENSG00000125538 ENSG00000105792 PMC4827226__F7 Working model of how the EphA1-activated SDF-1/CXCR4 signaling promotes EPCs’ homing to HCC neovascularization ENSG00000105656 ENSG00000121966 PMC7135251__F4 IPA cellular view of: A) 15 affected molecules in the significant Protein Ubiquitination pathway ENSG00000135655 ENSG00000137834 ENSG00000103266 ENSG00000142192 ENSG00000104343 ENSG00000157933 ENSG00000133937 ENSG00000070831 ENSG00000115297 ENSG00000156574 ENSG00000020633 ENSG00000105656 ENSG00000132478 ENSG00000164162 ENSG00000170242 ENSG00000170035 ENSG00000276561 ENSG00000101557 ENSG00000145604 ENSG00000160973 ENSG00000164093 ENSG00000175104 ENSG00000105821 PMC7846875__F10 Schematic drawing to illustrate the inhibitory effect of GPs on NFKB and TNFA signal pathway and inhibitory of apoptosis of endothelial and epithelial cells ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000162692 PMC5854325__F1 Death receptor-mediated apoptosis signaling ENSG00000102871 ENSG00000168040 ENSG00000026103 PMC7822913__F7 Hypothetic model of Abcc6 function in cholesterol homeostasis of mice ENSG00000005471 ENSG00000160752 ENSG00000197429 ENSG00000073734 ENSG00000169174 PMC9604914__F2 Bruton’s Tyrosine Kinase Inhibitors: The Next Frontier of B-Cell-Targeted Therapies for Cancer, Autoimmune Disorders, and Multiple Sclerosis ENSG00000177455 ENSG00000095585 ENSG00000105369 ENSG00000291971 ENSG00000186716 ENSG00000198793 ENSG00000124181 ENSG00000010671 PMC3899973__F1 Canonical signaling of muscarinic receptors ENSG00000291971 ENSG00000010810 ENSG00000138798 ENSG00000146648 PMC2761207__F1 Major pathway of the conversion of propionyl-CoA into succinyl-CoA in human cells ENSG00000110395 ENSG00000175198 ENSG00000114054 ENSG00000124370 ENSG00000151611 ENSG00000132763 PMC4352295__F3 Co-regulation analysis among 6 potential internal control genes (ICGs) ENSG00000137947 ENSG00000142192 ENSG00000111537 ENSG00000136997 ENSG00000089157 ENSG00000113520 ENSG00000134046 PMC3353386__F5 NS1 protein of influenza A virus suppresses interferon-regulated activation of antigen-presentation and immune-proteasome pathways ENSG00000224320 ENSG00000163131 ENSG00000232326 ENSG00000158825 ENSG00000125347 ENSG00000205220 PMC4259949__F1 Base-excision repair ENSG00000177084 PMC7099013__F2 Ingenuity pathway analysis of drug pharmacodynamic targets, associated immunophenotype markers and topo II ENSG00000136011 ENSG00000105472 PMC6679095__F2 The PI3K/AKT/mTOR/NFKB Pathway ENSG00000109452 ENSG00000198793 ENSG00000155792 ENSG00000164327 ENSG00000167965 PMC5528312__F2 RNF8‐ and RNF168‐dependent ubiquitin signaling pathway at DSBs is stimulated by CHD4‐ and p400‐mediated chromatin remodeling ENSG00000149311 ENSG00000012048 ENSG00000163961 ENSG00000112130 ENSG00000111642 PMC4614871__F3 Different regulation of DSB repair pathways in somatic cells and XY body ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000163961 ENSG00000070950 ENSG00000051180 ENSG00000112130 PMC2685917__F9 Cooperation of amphiregulin and insulin-like growth factor-1 inhibits Bax- and Bad-mediated apoptosis via a protein kinase C-dependent pathway in non-small cell lung cancer cells ENSG00000002330 ENSG00000146648 ENSG00000140443 PMC5216469__F3 Regulatory feedback mechanisms govern Etv2 expression ENSG00000105672 ENSG00000159200 ENSG00000179348 PMC3337715__F1 Phosphoinositide-3 kinase signaling in cardiac hypertrophy and heart failure ENSG00000002330 ENSG00000102034 ENSG00000169047 ENSG00000198793 ENSG00000164327 ENSG00000171791 PMC7278993__F8 Schematic diagram showing the pathways involved in the pathogenesis of vascular calcification (VC) in chronic kidney disease (CKD) ENSG00000154342 ENSG00000120057 ENSG00000168036 ENSG00000106483 PMC7328278__F8 Downregulated miR-18b (miR-18b-5p) signaling pathway in fALS linked SOD1 mutation ENSG00000171791 ENSG00000081189 PMC6329466__F1 Neurotrophic-tropomyosin receptor tyrosine kinase (NTRK) receptor signaling pathway and inhibitors PMC10950892__F2 Shows the benefits of Warburg and molecular signaling ENSG00000115419 ENSG00000159399 PMC11027102__F3 Blockade of the CD47-SIRPA signaling pathway initiates an adaptive immune response to kill tumor cells ENSG00000164430 ENSG00000198053 PMC7326282__F8 MicroRNA-18a targeting of the STK4/MST1 tumour suppressor is necessary for transformation in HPV positive cervical cancer ENSG00000101109 ENSG00000131023 PMC6285187__F8 Illustration of the working mechanisms for FGF21 prevention of spontaneous and diabetes-induced germ cell apoptosis ENSG00000105550 ENSG00000096717 PMC9207356__F2 Physiological and pathological roles of the Hippo‐YAP/TAZ signaling pathway in liver formation, homeostasis, and tumorigenesis ENSG00000144560 ENSG00000163914 ENSG00000114978 ENSG00000150457 ENSG00000131023 PMC7183688__F1 Participation of TNFAIP3 and UBE2L3 in regulation of NFKB activity under TNFA signaling ENSG00000137275 ENSG00000118503 ENSG00000185651 PMC7767977__F1 Illustration of the neuroprotective pathways following GHS-R1A activation by AG or ghrelin agonists in neurons and astrocytes ENSG00000177169 ENSG00000083290 ENSG00000116688 ENSG00000175567 ENSG00000096717 ENSG00000171109 ENSG00000057663 ENSG00000106459 PMC3733118__F2 Genes of innate immunity and the biological response to inhaled ozone ENSG00000026508 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC6384086__F11 Cofilin regulating the actin cytoskeleton and initiating PHEV entry ENSG00000159224 ENSG00000070831 PMC8983057__F5 Peripheral Blood Mononuclear Cell Gene Expression in Chronic Obstructive Pulmonary Disease: miRNA and mRNA Regulation ENSG00000163464 ENSG00000113070 ENSG00000163914 ENSG00000162692 PMC4647217__F10 microRNA-31 modulates skeletal patterning ENSG00000075891 ENSG00000196092 PMC7502313__F1 Endoplasmic Reticulum Stress Response in Male Reproductive Physiology and Pathology: A Review ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000171791 ENSG00000127191 PMC8103676__F7 Persistent Giant Algal Virus, with a Unique Morphology, Encodes an Unprecedented Number of Genes Involved in Energy Metabolism ENSG00000143252 ENSG00000182511 ENSG00000073578 ENSG00000117118 PMC312742__F9 Role of E2F1 in the DNA damage response ENSG00000149311 ENSG00000175054 ENSG00000112242 ENSG00000135446 ENSG00000282899 PMC7911501__F1 TLRs are involved in regulation of Mycobacterium tuberculosis (MTB)-induced production of proinflammatory cytokines ENSG00000239732 ENSG00000136869 PMC7751760__F5 Cellular pathways regulated by H2S in renal diseases ENSG00000010810 ENSG00000150907 ENSG00000172005 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000175104 PMC2860693__F8 Simplified model of the signaling pathways regulating radiation-induced bystander effects ENSG00000149311 ENSG00000138795 ENSG00000137033 ENSG00000168610 ENSG00000140443 PMC7870688__F1 Crosstalk of canonical and noncanonical TGFB signaling pathways associated with renal fibrosis and inflammation in diabetic nephropathy ENSG00000170365 PMC3012432__F7 Diagram illustrating the PS–Tyro3–Akt cell survival signaling pathways ENSG00000092445 ENSG00000002330 PMC10750202__F2 Regulatory mechanisms of circular RNAs during human mesenchymal stem cell osteogenic differentiation ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198742 ENSG00000168036 ENSG00000108840 PMC8355060__F1 Transcription Factors CREBH, PPARa, and FOXO1 as Critical Hepatic Mediators of Diet-Induced Metabolic Dysregulation ENSG00000042832 ENSG00000060566 PMC9083497__F5 Chronic activation of MUC1-C in wound repair promotes progression to cancer stem cells ENSG00000117713 ENSG00000163939 ENSG00000148400 ENSG00000168610 ENSG00000189079 ENSG00000166164 PMC7180296__F6 MetaCore‐based analysis of two major KEGG pathways and their regulatory gene interactions in skeletal and cardiac human fetal mesoangioblasts (MABs) ENSG00000175054 ENSG00000122180 ENSG00000166971 PMC5937716__F3 Functional Genome-wide Screen Identifies Pathways Restricting Central Nervous System Axonal Regeneration ENSG00000104321 ENSG00000106367 ENSG00000130643 ENSG00000116353 ENSG00000167941 ENSG00000148798 ENSG00000291791 ENSG00000134243 ENSG00000281857 ENSG00000062485 ENSG00000132341 PMC2655244__F8 Proposed model for the signaling pathway of Cao-induced keratinocyte differentiation ENSG00000143398 ENSG00000168036 PMC5704294__F1 Proposed activation pathway and domain structure of Nrf1 ENSG00000197312 ENSG00000178573 ENSG00000151092 ENSG00000106459 PMC11967982__F13 C-type lectin receptor signaling pathway (Pathway ID: hsa04625) from KEGG pathways ENSG00000162711 ENSG00000108691 ENSG00000102970 ENSG00000073910 PMC11985188__F4 Regulatory function of oncogenic and tumor suppressor long non-coding RNAs in p53 signaling pathway in the pathogenesis of esophageal cancer ENSG00000198492 ENSG00000123374 ENSG00000146457 ENSG00000160917 PMC11985188__F3 Regulatory function of oncogenic and tumor suppressor long non-coding RNAs in Wnt/Beta-catenin signaling pathway in the pathogenesis of esophageal cancer ENSG00000087245 ENSG00000169554 ENSG00000137166 ENSG00000168036 ENSG00000112715 PMC11985188__F2 Regulatory function of oncogenic and tumor suppressor long non-coding RNAs in PI3K/AKT/mTOR signaling pathway in the pathogenesis of esophageal cancer ENSG00000198793 ENSG00000143556 ENSG00000146648 PMC5467784__F7 Genes associated to tumorigenesis and/or cancer progression found differentially methylated in HA22T/VGH sorafenib treated cells ENSG00000023445 ENSG00000112576 ENSG00000137673 ENSG00000147862 ENSG00000133056 ENSG00000119535 ENSG00000135090 ENSG00000163568 ENSG00000198793 ENSG00000269335 ENSG00000124126 ENSG00000006062 ENSG00000168610 ENSG00000124762 ENSG00000292210 ENSG00000149968 ENSG00000101255 ENSG00000173757 ENSG00000067606 ENSG00000136327 ENSG00000164400 PMC6097681__F4 TLR4-mediated activation of the ERK pathway following UVA irradiation contributes to increased cytokine and MMP expression in senescent human dermal fibroblasts ENSG00000183979 ENSG00000168040 ENSG00000150455 ENSG00000111816 ENSG00000143387 ENSG00000150782 ENSG00000239732 ENSG00000184995 ENSG00000144410 ENSG00000170458 ENSG00000136869 ENSG00000175104 ENSG00000135517 PMC8379279__F1 Model assumptions ENSG00000291971 PMC5036929__F2 Drosophila JNK pathway ENSG00000175104 ENSG00000076604 PMC8103095__F3 miR‐33 regulates hepatic lipoprotein metabolism, fibrosis, and regeneration ENSG00000157933 ENSG00000138029 ENSG00000167910 ENSG00000113161 ENSG00000073734 ENSG00000105810 ENSG00000081923 ENSG00000005469 PMC4362780__F3 Poly(ADP-ribosyl)ation in DNA Damage Response and Cancer Chemotherapy ENSG00000012048 ENSG00000169621 ENSG00000134574 ENSG00000039650 ENSG00000137074 ENSG00000138385 PMC11985188__F7 Regulatory function of oncogenic and tumor suppressor long non-coding RNAs in MiR-Axis signaling pathway in the pathogenesis of esophageal cancer ENSG00000112715 PMC6492270__F1 In response to injury, there are significant and dynamic changes to the OGlcNAc sub-proteome ENSG00000147162 ENSG00000198408 ENSG00000185591 ENSG00000100219 PMC9551334__F9 Acute Manganese Exposure Modifies the Translation Machinery via PI3K/Akt Signaling in Glial Cells ENSG00000291971 ENSG00000167658 PMC7417625__F2 MALAT1 and miR-200c regulate expression of each other through the sponging mechanism ENSG00000169554 ENSG00000170558 PMC7912185__F2 Effect of Interventions in WNT Signaling on Healing of Cardiac Injury: A Systematic Review ENSG00000156076 ENSG00000281324 ENSG00000042832 ENSG00000162337 ENSG00000134982 ENSG00000155011 ENSG00000050165 ENSG00000169884 ENSG00000168036 ENSG00000106483 ENSG00000104332 PMC3328896__F2 Cbl-b functions as central gate keeper of T-cell activation ENSG00000291603 ENSG00000134982 ENSG00000010810 ENSG00000124181 ENSG00000141968 PMC6173124__F1 Role and regulation of host microRNAs in hepatic schistosomiasis ENSG00000137033 ENSG00000115415 ENSG00000168610 PMC10253263__F6 Signaling pathway of PNPLA3-I148M-induced activation of LX-2 cells ENSG00000087245 ENSG00000100344 ENSG00000116688 ENSG00000291748 ENSG00000160179 PMC5027901__F1 Listeria monocytogenes and the inflammasome: from cytosolic bacteriolysis to tumor immunotherapy ENSG00000163568 ENSG00000184216 PMC8389007__F8 Fisetin Inhibits NLRP3 Inflammasome by Suppressing TLR4/MD2-Mediated Mitochondrial ROS Production ENSG00000162711 ENSG00000125538 ENSG00000089041 ENSG00000136869 PMC3970924__F2 Molecular pathology of FLS in RA ENSG00000291971 ENSG00000177606 ENSG00000026103 PMC6198989__F6 Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk ENSG00000170962 ENSG00000118526 ENSG00000122691 ENSG00000163431 ENSG00000134853 ENSG00000151617 PMC7746877__F1 Signaling pathway of EMT ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC6612501__F1 TLR4-mediated inflammatory signaling pathway in the rumen epithelium ENSG00000111537 ENSG00000115415 ENSG00000172936 ENSG00000136869 PMC7746877__F2 Therapeutic potential of BMSC-derived exosomes for PF and the potential molecular mechanisms ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC3132567__F8 Cross-talk between Epidermal Growth Factor Receptor and Hypoxia-inducible Factor-1A Signal Pathways Increases Resistance to Apoptosis by Up-regulating Survivin Gene Expression ENSG00000134086 ENSG00000138798 ENSG00000146648 PMC8096065__F1 Sweet Melody or Jazz? Transcription Around DNA Double-Strand Breaks ENSG00000143799 ENSG00000012061 ENSG00000149311 ENSG00000132646 ENSG00000291803 ENSG00000130997 ENSG00000051180 ENSG00000139618 PMC7689008__F1 Cell adhesion molecules (CAMs) regulate protein synthesis machinery ENSG00000291971 ENSG00000010810 ENSG00000198793 PMC10215085__F9 Hypothetical molecular mechanism model was developed for the influence of starch on the growth and proliferation of B ENSG00000138622 ENSG00000099822 PMC9578583__F3 Diagram representing the enzymes involved in the 11 steps of the glycolytic and methylglyoxal pathway and tricarboxylic cycle found in the rumen epithelium of sheep ENSG00000065833 ENSG00000063854 ENSG00000105953 ENSG00000110435 ENSG00000166816 ENSG00000091140 ENSG00000062485 PMC6677558__F1 Model of the regulation of light-mediated AS ENSG00000261701 PMC7322557__F1 Molecular connections between components of circadian clocks and the immune system ENSG00000108691 ENSG00000143546 ENSG00000165030 ENSG00000108700 ENSG00000121807 ENSG00000069667 PMC3662247__F3 PAMPs and DAMPs: Signal 0s that Spur Autophagy and Immunity ENSG00000132906 ENSG00000124102 ENSG00000177169 ENSG00000110497 ENSG00000198382 ENSG00000198793 ENSG00000158828 ENSG00000168040 ENSG00000164305 ENSG00000057663 ENSG00000062716 ENSG00000189403 ENSG00000078237 ENSG00000120868 ENSG00000175104 ENSG00000145782 PMC6606851__F8 Pathway activity measured with luciferase reporters for canonical signaling (STF) ENSG00000154342 ENSG00000169071 ENSG00000134982 ENSG00000168036 PMC3662247__F4 PAMPs and DAMPs: Signal 0s that Spur Autophagy and Immunity ENSG00000174125 ENSG00000163568 ENSG00000150455 ENSG00000276561 ENSG00000183735 ENSG00000188554 ENSG00000239732 ENSG00000187554 ENSG00000272398 ENSG00000189403 ENSG00000136869 ENSG00000172936 ENSG00000175104 ENSG00000164342 PMC5521727__F1 Hsp90 and Physiological Stress Are Linked to Autonomous Transposon Mobility and Heritable Genetic Change in Nematodes ENSG00000130997 PMC12131761__F1 Analysis flowchart ENSG00000135517 PMC7522761__F1 Interferon signaling from dermatomyositis skin analysis ENSG00000213928 ENSG00000111537 ENSG00000105397 ENSG00000033800 ENSG00000185745 ENSG00000125347 ENSG00000230034 PMC1995599__F2 MOLECULAR AND CELLULAR MECHANISMS OF THE ANABOLIC EFFECT OF INTERMITTENT PTH ENSG00000152266 ENSG00000002330 ENSG00000198742 PMC8257499__F5 Rare copy-number variants (CNVs) in spina bifida (SB) cases participate in SB-relevant pathways and affect various aspects of one-carbon metabolism ENSG00000164904 ENSG00000135407 ENSG00000132840 ENSG00000291720 PMC12158998__F6 Molecular targets and mechanisms of cortex mori for lung cancer treatment: a network pharmacology study, molecular docking and in vitro and in vivo experimental validation ENSG00000068028 ENSG00000132906 ENSG00000189283 ENSG00000002330 ENSG00000138798 ENSG00000171759 ENSG00000122008 PMC7522761__F2 Ingenuity Pathway Analysis of candidate genes downstream of interferon-alpha signaling from dermatomyositis skin analysis ENSG00000169245 ENSG00000213928 ENSG00000134321 ENSG00000187608 ENSG00000115415 ENSG00000136997 ENSG00000125347 ENSG00000168610 ENSG00000276561 PMC12158998__F5 Molecular targets and mechanisms of cortex mori for lung cancer treatment: a network pharmacology study, molecular docking and in vitro and in vivo experimental validation ENSG00000145604 ENSG00000132906 ENSG00000189283 ENSG00000123374 ENSG00000164305 ENSG00000122008 PMC7522761__F5 Ingenuity pathway analysis of several candidate genes with oncogenic and tumor suppressing properties downstream of IFNG signaling ENSG00000213928 ENSG00000181163 ENSG00000100906 ENSG00000140968 ENSG00000125347 ENSG00000168610 ENSG00000276561 ENSG00000111537 ENSG00000133110 ENSG00000115415 ENSG00000136997 ENSG00000125538 ENSG00000026508 PMC7522761__F4 Ingenuity Pathway Analysis of candidate genes downstream of interferon-alpha signaling from dermatomyositis muscle analysis ENSG00000138378 ENSG00000224320 ENSG00000108515 ENSG00000115415 ENSG00000072274 ENSG00000136997 ENSG00000173039 ENSG00000026508 ENSG00000110218 ENSG00000168610 PMC6567055__F1 Tumor-associated macrophage (TAM) function in the ovarian cancer tumor microenvironment (TME) and examples of therapeutic strategies ENSG00000102962 ENSG00000108691 ENSG00000275385 ENSG00000198053 PMC8786484__F6 Study on the Mechanism of Fentanyl in Pain Treatment Based on Network Pharmacology ENSG00000142192 ENSG00000158825 PMC11815730__F3 Hippo signaling pathway components in mammals ENSG00000197905 ENSG00000150457 ENSG00000131023 PMC3815562__F1 Outline of steps mediating androgen synthesis and metabolism in prostate cancer cells ENSG00000151632 ENSG00000197888 ENSG00000203857 ENSG00000187134 PMC4490529__F7 Schematic model of DMF-induced neuroprotection in rat NPCs and differentiated neurons ENSG00000181019 ENSG00000167996 ENSG00000271303 PMC5528384__F7 Cyclophosphamide (CTX)‐mediated immunomodulation on the basis of genes up‐regulated by treatment ENSG00000081041 ENSG00000187796 ENSG00000291971 PMC3033602__F1 Adapted from KEGG colorectal cancer pathway [, , ] ENSG00000132906 ENSG00000134982 PMC8485019__F1 Bile reflux and hypopharyngeal cancer ENSG00000125538 ENSG00000168610 ENSG00000146648 PMC3662247__F6 PAMPs and DAMPs: Signal 0s that Spur Autophagy and Immunity ENSG00000170458 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC9600942__F5 Tumor-Infiltrating Dendritic Cells: Decisive Roles in Cancer Immunosurveillance, Immunoediting, and Tumor T Cell Tolerance ENSG00000108691 ENSG00000184371 ENSG00000049768 PMC11840835__F3 Diagram of mechanisms of glucose controlling the fate of blastocyst ENSG00000087510 ENSG00000165556 ENSG00000198793 ENSG00000197905 PMC7062300__F2 MS identification, quantification and analysis of protein meK modifications in human platelets ENSG00000184220 ENSG00000197043 ENSG00000108395 ENSG00000146872 ENSG00000154001 ENSG00000006715 ENSG00000148606 ENSG00000172037 ENSG00000139218 ENSG00000102189 ENSG00000203485 ENSG00000139220 ENSG00000261150 ENSG00000171793 ENSG00000084733 ENSG00000113263 ENSG00000205937 ENSG00000163644 ENSG00000160460 ENSG00000124787 ENSG00000130741 ENSG00000197081 ENSG00000173674 ENSG00000167658 ENSG00000116127 ENSG00000143933 ENSG00000157106 ENSG00000157212 ENSG00000165794 ENSG00000167522 ENSG00000137877 ENSG00000164961 ENSG00000133858 ENSG00000221823 ENSG00000143514 ENSG00000107020 ENSG00000115415 ENSG00000129646 ENSG00000137992 ENSG00000139116 ENSG00000131018 ENSG00000163848 ENSG00000125450 ENSG00000159111 ENSG00000121060 ENSG00000082212 ENSG00000105379 ENSG00000136205 PMC7407354__F1 Scheme of the amino acid (AA)-related energy metabolic pathway shows the amino acids and their metabolites in the nontumor and tumor regions ENSG00000173599 ENSG00000124253 ENSG00000115419 PMC4037996__F2 Role of normal and mutated KRAS protein in the regulation of the signalling pathway associated with EGFR activation ENSG00000138798 ENSG00000146648 PMC4037996__F1 Intracellular signalling pathway originating at EGFR and inducing the activation of proliferation, inhibition of apoptosis, and differentiation of epithelial and cancer cells ENSG00000163235 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000136997 ENSG00000146648 PMC2193492__F1 Pathways initiating transcription from pIV of the CIITA gene ENSG00000115415 PMC6105527__F2 Cut loose and run: The complex role of ADAM proteases during neural crest cell development ENSG00000039537 ENSG00000065361 ENSG00000136997 ENSG00000137203 PMC7598701__F10 Differentially expressed genes involved in the p53 signaling pathway were annotated by KEGG ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000136997 ENSG00000042286 ENSG00000123374 ENSG00000112378 ENSG00000196470 PMC5016207__F2 Factors involved in the ontogeny of fetal Leydig cells ENSG00000104899 ENSG00000019991 ENSG00000157404 ENSG00000090402 ENSG00000168066 ENSG00000285109 ENSG00000135409 ENSG00000120088 ENSG00000139549 ENSG00000004848 PMC7898445__F8 Signalling pathway of Eno-RPSA induced the loss of BBB integrity ENSG00000168028 ENSG00000136869 PMC9407997__F2 Genetic Variants Associated with Elevated Plasma Ceramides in Individuals with Metabolic Syndrome ENSG00000139624 ENSG00000198964 ENSG00000100596 ENSG00000154227 ENSG00000164023 ENSG00000188611 ENSG00000172296 ENSG00000143418 ENSG00000135587 PMC7917224__F8 Cardiac Gq Receptors and Calcineurin Activation Are Not Required for the Hypertrophic Response to Mechanical Left Ventricular Pressure Overload ENSG00000285109 PMC5310224__F3 The unfolded protein response in immunity and inflammation ENSG00000128272 ENSG00000125538 ENSG00000136869 ENSG00000175104 PMC5856749__F5 NRF2-mediated oxidative stress response –signaling in the nucleus ENSG00000166794 ENSG00000128272 ENSG00000178573 ENSG00000177606 ENSG00000167996 ENSG00000117707 ENSG00000125656 ENSG00000176153 ENSG00000138356 ENSG00000101557 PMC6858307__F1 MDC1 loss causes greater IR sensitivity than H2AX loss ENSG00000188486 ENSG00000149311 ENSG00000163961 ENSG00000112130 PMC7775612__F2 Cell signaling pathways activated in acute inflammation induced by carbon nanotubes (CNTs) ENSG00000162711 ENSG00000125538 ENSG00000115594 PMC6650359__F6 Proposed pathway for the role of OLA1 in ANG II-induced cardiac hypertrophy ENSG00000175206 ENSG00000092054 ENSG00000168036 PMC11677578__F11 Arachidonic acid metabolism pathway ENSG00000173599 ENSG00000148344 PMC3819050__F2 Wnt7a signals bi-directionally at vertebrate synapses ENSG00000107404 ENSG00000154764 PMC7232598__F4 Ingenuity Pathway Analysis (IPA) network diagram of differentially expressed genes in patient vs ENSG00000291527 ENSG00000117650 ENSG00000291814 ENSG00000163221 ENSG00000171202 ENSG00000164332 ENSG00000100526 ENSG00000004766 PMC9641390__F3 Targetable vulnerability of deregulated FOXM1/PLK1 signaling axis in diffuse large B cell lymphoma ENSG00000167601 ENSG00000125482 ENSG00000284161 ENSG00000164327 ENSG00000166851 ENSG00000168610 ENSG00000121966 ENSG00000149311 ENSG00000175054 ENSG00000134057 ENSG00000115457 ENSG00000074181 ENSG00000132646 ENSG00000114315 ENSG00000095002 ENSG00000115461 PMC4408853__F1 Neuronal Ca2+signalling toolkit ENSG00000167323 ENSG00000293604 ENSG00000109689 PMC11677578__F10 Autophagy–animal pathway ENSG00000198793 ENSG00000078804 PMC7716168__F6 The role of MOB1A in the survival of GBC cells under glucose-deprivation conditions ENSG00000114978 ENSG00000168610 PMC4069059__F7 Receptor Interactive Protein Kinase 3 Promotes Cisplatin-Triggered Necrosis in Apoptosis-Resistant Esophageal Squamous Cell Carcinoma Cells ENSG00000132906 ENSG00000137275 ENSG00000177606 ENSG00000168404 ENSG00000164305 ENSG00000285379 PMC3928158__F1 Signal transduction of Helicobacter pylori during interaction with host cell protein receptors of epithelial and immune cells ENSG00000019582 ENSG00000167207 ENSG00000136997 ENSG00000117335 PMC8100412__F9 Integrated Molecular Docking with Network Pharmacology to Reveal the Molecular Mechanism of Simiao Powder in the Treatment of Acute Gouty Arthritis ENSG00000090402 ENSG00000168066 ENSG00000178573 ENSG00000102871 ENSG00000186051 PMC7070171__F8 Schema showing the major roles of butyrate in inhibiting atherosclerosis of mice in this study ENSG00000214456 ENSG00000288174 ENSG00000167910 ENSG00000185591 ENSG00000160179 ENSG00000112299 PMC5227296__F4 Cordycepin function in chondrogenesis and chondrocyte hypertrophy of MSCs ENSG00000148400 PMC3064890__F5 BRCA2/RAD51 pathway in the response to stalled forks ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000158636 ENSG00000132646 ENSG00000139618 PMC3064890__F4 BRCA2/RAD51 pathway in response to DSBs ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000158636 ENSG00000139618 PMC3540089__F1 PORPHOBILINOGEN DEAMINASE Deficiency Alters Vegetative and Reproductive Development and Causes Lesions in Arabidopsis ENSG00000144410 ENSG00000126088 ENSG00000188690 PMC7068849__F4 Regulation/function of IL-17 secreting cells during candidiasis ENSG00000187796 ENSG00000134982 ENSG00000125538 PMC3412625__F6 Combination therapy with VELCADE and tPA is neuroprotective in aged rats after stroke and targets miRNA-146a and the toll-like receptor signaling pathway ENSG00000136869 ENSG00000100985 ENSG00000184216 PMC8316858__F8 Investigating the Pharmacological Mechanisms of SheXiang XinTongNing Against Coronary Heart Disease Based on Network Pharmacology and Experimental Evaluation ENSG00000132906 ENSG00000002330 ENSG00000164305 PMC4249809__F1 Role of TGF-beta in healthy and OA cartilage ENSG00000170365 ENSG00000125398 PMC6719163__F6 Nobiletin-induced apoptotic pathway in bladder cancer cells ENSG00000128272 ENSG00000002330 ENSG00000144895 ENSG00000198793 PMC4040287__F4 SIRT1 in neurodevelopment and brain senescence ENSG00000284774 ENSG00000067900 ENSG00000096717 ENSG00000137845 PMC9138898__F1 Controlling Cancer Cell Death Types to Optimize Anti-Tumor Immunity ENSG00000132906 ENSG00000064012 ENSG00000164305 PMC4974939__F3 Activation of “RNA-sensing” TLRs on neurons and microglia triggers distinct effects ENSG00000164342 PMC7150781__F3 HBV suppression of type I interferon (IFN) response (Green arrows indicate the related signaling pathways and T-arrows in red indicate blocking the targets) ENSG00000183735 ENSG00000213928 ENSG00000088888 ENSG00000089127 ENSG00000164342 PMC7868824__F8 Overall, pyrazole significantly up-regulate E-cadherin expression and regulated MMP-2 expression in A549 cells ENSG00000136869 ENSG00000146648 PMC6523735__F6 Proposed model for miR-130a downregulation of HCV infection ENSG00000262785 ENSG00000145782 ENSG00000057663 PMC10308132__F1 Targeting SAMHD1: To overcome multiple anti-cancer drugs resistance in hematological malignancies ENSG00000164430 ENSG00000145386 ENSG00000175104 ENSG00000276561 PMC11799893__F3 Transcriptome analysis of isopentanol synthesis pathways ENSG00000180210 ENSG00000143158 ENSG00000060762 PMC5599481__F4 Overview of arachidonic acid cascade associated with inflammatory pain response ENSG00000226275 PMC5842623__F1 Mammalian target of rapamycin (mTOR) signaling pathway ENSG00000140992 ENSG00000168209 ENSG00000104365 ENSG00000114388 ENSG00000171105 ENSG00000157764 ENSG00000198793 ENSG00000169047 ENSG00000155792 ENSG00000164327 ENSG00000213341 ENSG00000141564 ENSG00000167965 ENSG00000145604 ENSG00000101407 ENSG00000168003 ENSG00000106070 ENSG00000135932 ENSG00000204673 ENSG00000134324 ENSG00000118515 ENSG00000176641 ENSG00000186654 PMC5684300__F2 Simplified diagram depicting canonical and non canonical Beta-catenin signalling pathways in bone ENSG00000152266 ENSG00000169071 ENSG00000134982 ENSG00000168036 PMC2852112__F2 Anti-viral and pro-viral functions of autophagy ENSG00000144895 ENSG00000145782 ENSG00000057663 PMC2852112__F1 Scheme of the autophagy pathway ENSG00000152348 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC7701249__F2 Iron metabolism-related pathway in ferroptosis PMC9059101__F11 Critical and Diverse Roles of CD4–CD8– Double Negative T Cells in Nonalcoholic Fatty Liver Disease ENSG00000135218 ENSG00000112115 PMC5778882__F1 The Axl signaling pathway ENSG00000167601 ENSG00000062598 ENSG00000291971 ENSG00000168610 PMC11599216__F4 Crossroads of epigenetics and immune pathways ENSG00000117139 ENSG00000172936 ENSG00000175104 ENSG00000165819 ENSG00000126012 ENSG00000197724 PMC5333072__F1 MNT and its place in the MAX-MLX network of interacting proteins ENSG00000281178 ENSG00000070444 ENSG00000123933 ENSG00000136997 ENSG00000174197 ENSG00000116990 ENSG00000108788 ENSG00000213347 PMC5495965__F2 Predicted interactions among proteins encoded by genes expressed differentially in late proestrus ENSG00000112038 ENSG00000091664 ENSG00000069482 ENSG00000082175 ENSG00000101438 ENSG00000170498 ENSG00000121853 ENSG00000134243 ENSG00000175567 ENSG00000165646 PMC4698356__F2 Proteins highlighted for their contributions to molecular regulation in diabetes and heart failure ENSG00000198408 ENSG00000167323 ENSG00000185591 PMC3345192__F1A MYC on the Path to Cancer ENSG00000136997 ENSG00000168036 PMC7850464__F1 B7-H1/PD-1 signaling pathway in osteosarcoma ENSG00000094631 ENSG00000134982 ENSG00000168610 PMC2916838__F8 NPRL2 Sensitizes Human Non-Small Cell Lung Cancer (NSCLC) Cells to Cisplatin Treatment by Regulating Key Components in the DNA Repair Pathway ENSG00000149311 ENSG00000114388 PMC7035145__F13 Schematic showing integration of inputs in the SIP syncytium ENSG00000146469 ENSG00000134853 PMC8224368__F2 Combined Single Nucleotide Variants of ORAI1 and BLK in a Child with Refractory Kawasaki Disease ENSG00000143226 ENSG00000164305 ENSG00000086544 PMC8998982__F2 Cyclin-Dependent Kinase Synthetic Lethality Partners in DNA Damage Response ENSG00000167258 ENSG00000115902 ENSG00000178999 ENSG00000142230 ENSG00000087586 ENSG00000166851 ENSG00000100029 ENSG00000136807 ENSG00000168003 ENSG00000175054 ENSG00000141867 ENSG00000128272 ENSG00000136997 ENSG00000146648 ENSG00000159399 ENSG00000084774 PMC8998982__F1 Cyclin-Dependent Kinase Synthetic Lethality Partners in DNA Damage Response ENSG00000167513 ENSG00000112118 ENSG00000073111 ENSG00000076003 ENSG00000118971 ENSG00000166508 ENSG00000093009 ENSG00000094804 ENSG00000135446 ENSG00000132646 ENSG00000165392 ENSG00000136997 ENSG00000123374 ENSG00000105810 ENSG00000177084 PMC5006314__F7 Inhibitory effect of NBL1 on PDGF-BB-induced human PASMC proliferation through blockade of PDGFBeta-p38MAPK pathway ENSG00000135446 ENSG00000158747 PMC3170700__F1 Activation of cellular responses during ER stress ENSG00000128272 ENSG00000144895 ENSG00000188404 PMC6770886__F2 Rac3-mediated mechanisms in cancer ENSG00000169750 ENSG00000105251 ENSG00000165527 ENSG00000160293 PMC7074533__F3 The vascular smooth muscle contraction pathway ENSG00000175206 ENSG00000148926 ENSG00000188784 ENSG00000088256 ENSG00000131477 ENSG00000170890 ENSG00000163017 ENSG00000101333 ENSG00000160013 ENSG00000081248 ENSG00000110680 ENSG00000122786 ENSG00000152402 ENSG00000159899 ENSG00000143933 ENSG00000067900 ENSG00000101306 ENSG00000087460 ENSG00000124205 ENSG00000120937 ENSG00000129007 ENSG00000185532 ENSG00000151617 ENSG00000162104 ENSG00000156113 PMC5520734__F7 Schematic diagram of G0/G1 phase arrest and ROS-dependent MAPKs pathway in which furanodienone induces cell growth inhibition and cell death in CRC cells ENSG00000132906 ENSG00000135446 ENSG00000105810 ENSG00000064012 PMC6211194__F2 Simplified metabolic pathway of ∆9-tetrahydrocannabinol (THC), or ∆1-tetrahydrocannabinol, under the monoterpenoid naming system, in humans PMC5549626__F2 PLCG1 deficiency perturbs phosphorylation on canonical TCR signaling proteins ENSG00000135218 ENSG00000213658 ENSG00000070831 ENSG00000177606 ENSG00000197943 ENSG00000162924 ENSG00000113263 ENSG00000124181 ENSG00000141968 PMC5587804__F4 Differential metaMIR analysis recovers miRNAs involved in cancer ENSG00000107779 ENSG00000116254 ENSG00000170365 ENSG00000186575 ENSG00000105329 ENSG00000183691 ENSG00000136997 ENSG00000187140 ENSG00000204217 ENSG00000196712 PMC6049516__F1 Altered Hippo pathway signaling contributes to the kidney cystogenesis in Pkd1 mutant ADPKD ENSG00000008710 PMC9580211__F8 CapG promoted nasopharyngeal carcinoma cell motility involving Rho motility pathway independent of ROCK ENSG00000163914 PMC8511707__F1 Fatty Acids Derivatives From Eukaryotic Microalgae, Pathways and Potential Applications ENSG00000026103 PMC4788885__F5 Wnt signaling pathway ENSG00000087095 ENSG00000100592 ENSG00000100387 ENSG00000134982 ENSG00000147869 ENSG00000113558 ENSG00000196470 PMC11512478__F8 Mechanism of CHRDL1-MED29-mediated interruption of EMT evolution in OSCC ENSG00000063322 ENSG00000101938 ENSG00000170558 ENSG00000132478 PMC4144918__F1 Do Mantle Cell Lymphomas have an “Achilles Heel”? ENSG00000104856 ENSG00000149311 ENSG00000135446 ENSG00000186716 ENSG00000198793 ENSG00000131323 ENSG00000105810 ENSG00000171791 ENSG00000127191 ENSG00000010671 ENSG00000198625 PMC3843232__F1 Causal role for JAK2 V617F in thrombosis ENSG00000117400 PMC6611921__F4 Pathway map based on renal age-associated gene (RAAGs).Enriched molecular pathways based on the set of 634 RAAGs are displayed ENSG00000164761 ENSG00000138798 ENSG00000198793 ENSG00000124875 PMC6073901__F2 Proposed model for a signaling network between Notch, HIF-1A, and GPER in cancer epithelial-mesenchymal-transition (EMT) ENSG00000148400 PMC8924146__F4 MicroRNAs as a clue to overcome breast cancer treatment resistance ENSG00000157554 ENSG00000124882 ENSG00000198793 ENSG00000146648 ENSG00000140443 PMC3979163__F1 The canonical Wnt signaling pathway ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC8093869__F1 Neuroinflammation in HIV-Related Neuropathic Pain ENSG00000168329 ENSG00000169071 ENSG00000173599 ENSG00000164305 ENSG00000121966 PMC4424147__F1 Receptor-mediated activation of PI3K-Akt pathway and signaling ENSG00000002330 ENSG00000186716 ENSG00000198793 ENSG00000040199 PMC6325856__F10 The proposed cardioprotective mechanism of mAb A treatment in hearts following a myocardial infarction ENSG00000198793 ENSG00000163884 PMC6692500__F5 Sodium and potassium loci in behavior, thermoregulation, and weight loss networks ENSG00000115226 ENSG00000105550 ENSG00000136531 ENSG00000021645 ENSG00000255974 ENSG00000115896 ENSG00000106546 ENSG00000221823 ENSG00000172260 ENSG00000009950 ENSG00000170927 ENSG00000179029 ENSG00000170382 ENSG00000115526 ENSG00000078725 PMC9616118__F9 Meritorious integrated medical regimen for hepatic fibrosis and its complications via the systematic review and meta-analysis for Dahuang Zhechong pill-based therapy ENSG00000095739 ENSG00000172936 ENSG00000164690 ENSG00000128602 PMC3520542__F13 Molecular mechanism for Elovl5 control of mTORC2, FoxO1-S256 phosphorylation, and hepatic GNG ENSG00000170522 ENSG00000134824 ENSG00000149485 ENSG00000197977 ENSG00000169710 ENSG00000164327 ENSG00000124253 PMC7905058__F3 Gain-of-function of mutant p53 over proliferation, invasion and metastasis ENSG00000079387 ENSG00000165119 ENSG00000136848 PMC5977062__F1 Diverse regulatory mechanisms of ncRNAs on Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5542021__F1 Signaling pathways for selected transcripts that regulate dendritic spine density ENSG00000163171 ENSG00000070831 ENSG00000149269 ENSG00000170558 PMC406534__F1 Proteolytic processing of APP is divided into an amyloidogenic and an antiamyloidogenic pathway ENSG00000142192 ENSG00000137845 PMC9563036__F3 Emerging Role of Pericyte-Derived Extracellular Vesicles in Vascular and Neurological Health ENSG00000140575 PMC9563036__F4 Emerging Role of Pericyte-Derived Extracellular Vesicles in Vascular and Neurological Health ENSG00000171791 PMC7351826__F7 Hypothesis that Sal B protects myocardium through inhibiting the expression of HMGB1 via activating PI3k/Akt signalling pathway in myocardial I/R injury ENSG00000189403 ENSG00000136869 PMC11635239__F8 LPS induces the upregulation of activin-A in recAMs, which can drive the EMT process by activating the TGF-Beta-SMAD signaling axis PMC3275780__F2 T cell activation ENSG00000291603 ENSG00000291971 ENSG00000134982 PMC6319725__F10 Transcriptomic characterization of signaling pathways associated with osteoblastic differentiation of MC-3T3E1 cells ENSG00000105835 PMC10905894__F4 Molecular mechanism of resveratrol promoting differentiation of preosteoblastic MC3T3-E1 cells based on network pharmacology and experimental validation ENSG00000132906 ENSG00000149311 ENSG00000291983 ENSG00000138794 ENSG00000168040 ENSG00000127191 ENSG00000135116 ENSG00000084774 ENSG00000115317 PMC7849651__F6 Summary of the potential pathways about exogenous antigen 11S processing and presentation in the distal intestine ENSG00000110711 ENSG00000198793 ENSG00000163914 ENSG00000158825 ENSG00000166278 ENSG00000139154 PMC9563451__F2 Colorectal Cancer and Purinergic Signalling: An Overview ENSG00000196839 ENSG00000110218 PMC7071425__F9 Elav1 pathway for mRNA stabilization ENSG00000126883 PMC3246369__F2 Small RNAs in transcriptional gene silencing and genome defence ENSG00000166869 ENSG00000187446 ENSG00000198576 ENSG00000092847 PMC5739664__F7 Indirubin, a bisindole alkaloid from Isatis indigotica, reduces H1N1 susceptibility in stressed mice by regulating MAVS signaling ENSG00000183735 ENSG00000088888 PMC8431321__F2 Interplay between Hepatitis E Virus and Host Cell Pattern Recognition Receptors ENSG00000183735 ENSG00000088888 ENSG00000198053 ENSG00000172663 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC12015515__F1 Novel signaling pathway linking IL18 proteolytic processing to anticancer immunity ENSG00000187608 ENSG00000115415 ENSG00000132964 ENSG00000164305 PMC9052234__F2 Cytokines in Abdominal Aortic Aneurysm: Master Regulators With Clinical Application ENSG00000169245 ENSG00000137033 ENSG00000125538 ENSG00000121807 ENSG00000121966 ENSG00000197461 PMC8358715__F2 Hypoxia‐inducible factor‐1 drives divergent immunomodulatory functions in the pathogenesis of autoimmune diseases ENSG00000138378 ENSG00000049768 ENSG00000106546 PMC3417165__F1 PI3K/AKT signaling pathway in Tregs ENSG00000049768 PMC8875876__F4 Effects of Stress and Diet on the “Brain–Gut” and “Gut–Brain” Pathways in Animal Models of Stress and Depression ENSG00000139287 ENSG00000129167 PMC8124456__F1 CD26/DPP-4: Type 2 Diabetes Drug Target with Potential Influence on Cancer Biology ENSG00000107562 ENSG00000197635 ENSG00000198793 ENSG00000121966 PMC3215886__F2 The “inhibitory” pathway of WNK4 ENSG00000196632 ENSG00000126562 ENSG00000060237 PMC7313089__F2 Involvement of ubiquitin in the key signaling pathways important for IFN production and IFN responses ENSG00000183735 ENSG00000164430 ENSG00000088888 PMC6510543__F1 A sugar rush for innate immunity ENSG00000073331 ENSG00000145365 ENSG00000175104 PMC8746116__F6 Relationships between type 2 diabetes, cell dysfunction, and redox signaling: A meta‐analysis of single‐cell gene expression of human pancreatic A‐ and B‐cells ENSG00000170899 ENSG00000116044 ENSG00000181019 ENSG00000284099 ENSG00000292209 ENSG00000023909 ENSG00000186104 ENSG00000079999 PMC3104579__F1 RhoA/ROCK I pathway and remodeling of microtubule network underlie the polarization and migration of HSPCs ENSG00000178860 ENSG00000026508 ENSG00000174059 ENSG00000076662 ENSG00000121966 PMC195990__F5 A model of Hip1's role in lung branching morphogenesis ENSG00000070193 ENSG00000164690 PMC12234736__F5 LLPS regulates immune cell alterations during adaptive immunity ENSG00000213658 ENSG00000186716 PMC12234736__F4 Phase separation is associated with cGAS-related inflammation ENSG00000183735 ENSG00000164430 ENSG00000088888 ENSG00000121060 ENSG00000276561 PMC12234736__F3 Sufu prevents sepsis by disrupting the LLPS of TRAF6 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC9573972__F1 Unraveling the mechanobiology of cornea: From bench side to the clinic ENSG00000125398 ENSG00000163914 ENSG00000136997 ENSG00000168036 ENSG00000118777 PMC4480706__F8 HDAC9 promotes glioblastoma growth via TAZ-mediated EGFR pathway activation ENSG00000048052 ENSG00000123374 ENSG00000146648 PMC6107301__F8 The conversion of a T:G mispair to a T:A mutation by guanine oxidation followed by long-patch base excision repair ENSG00000134982 PMC2890409__F1 Classification of Dengue Fever Patients Based on Gene Expression Data Using Support Vector Machines ENSG00000239732 ENSG00000172936 ENSG00000107201 ENSG00000276561 ENSG00000164342 PMC4551447__F1 Decade in Review-Kidney Cancer Kidney cancer's decade—discoveries, therapies and opportunities ENSG00000163930 ENSG00000134086 ENSG00000181555 ENSG00000127616 PMC3653146__F1 Possible signal pathway activated by cathelicidin (LL-37) to inhibit cell proliferation in gastric cancer cells ENSG00000170365 ENSG00000123374 ENSG00000175305 PMC7393681__F2 More RAS vulnerabilities, downstream ENSG00000136807 ENSG00000198793 ENSG00000136997 PMC8709003__F3 Inflammatory Effects of Bothrops Phospholipases A2: Mechanisms Involved in Biosynthesis of Lipid Mediators and Lipid Accumulation ENSG00000172936 PMC11174838__F3 Resistance Exercise and Essential Amino Acid Intake on Muscle Quality, Myokine, and Inflammation Factors in Young Adult Males ENSG00000198793 PMC11763651__F1 Biosynthesis of BH4 and genetic diseases due to BH4 deficiency ENSG00000228716 PMC3618895__F4 Significantly changing expression sub-networks in LMB hypothalamus ENSG00000079387 ENSG00000109163 ENSG00000184845 ENSG00000105329 ENSG00000100906 ENSG00000242110 ENSG00000115138 ENSG00000115718 ENSG00000164344 ENSG00000274665 ENSG00000011347 ENSG00000149295 PMC4152244__F1 Immunohistochemical Analysis of the Mechanistic Target of Rapamycin and Hypoxia Signalling Pathways in Basal Cell Carcinoma and Trichoepithelioma ENSG00000198793 ENSG00000112715 PMC4575550__F1 Effects of exercise on the signalling pathways associated with muscle growth and wasting in sarcopenia and cachexia ENSG00000198793 PMC5841108__F11 Schematic representation of miR-34a regulating SIRT1/AMPKA signaling pathways and Egr1 involved in the HG-induced fibrosis and inflammation in RMCs ENSG00000096717 PMC12152632__F11 Proposed mechanism of TX's neuroprotection against Mn toxicity by upregulating REST expression via Wnt/Beta-catenin signaling in CAD neurons ENSG00000154342 ENSG00000084093 ENSG00000281324 ENSG00000162337 PMC3621754__F3 MUC1-C Oncoprotein as a Target in Breast Cancer; Activation of Signaling Pathways and Therapeutic Approaches ENSG00000291971 ENSG00000198793 ENSG00000146648 PMC4008387__F2 Molecular mechanisms of hepcidin regulation ENSG00000170365 ENSG00000140564 ENSG00000106327 ENSG00000187045 ENSG00000105697 ENSG00000168610 ENSG00000130513 PMC4278318__F1 NMI and EMT ENSG00000115415 ENSG00000123609 PMC3621754__F6 MUC1-C Oncoprotein as a Target in Breast Cancer; Activation of Signaling Pathways and Therapeutic Approaches ENSG00000115415 ENSG00000102871 ENSG00000173039 ENSG00000127191 ENSG00000168610 PMC3621754__F5 MUC1-C Oncoprotein as a Target in Breast Cancer; Activation of Signaling Pathways and Therapeutic Approaches ENSG00000291971 ENSG00000168036 ENSG00000146648 PMC8143046__F2 Interplay of Glucagon-Like Peptide-1 Receptor Trafficking and Signalling in Pancreatic Beta Cells ENSG00000157500 ENSG00000143376 ENSG00000117298 ENSG00000028528 PMC5881178__F4 Metabolomic differences associated with Wnt1-initiated tumors ENSG00000129596 ENSG00000125084 PMC8911130__F1 An Assessment of Selected Molecular and Biochemical Markers of the Folate Pathway as Potential Risk Factors for Fetal Trisomy 21 during the First Trimester of Pregnancy in the Polish Population ENSG00000124275 ENSG00000116984 PMC7923226__F2 Main molecular mechanism of actions deployed by the anticancer peptides presented in this review ENSG00000132906 ENSG00000168040 ENSG00000164305 PMC8046990__F9 NAD+-SIRT1 signaling fine-tunes the activity of key transcription factor networks to promote adipocyte function ENSG00000174156 ENSG00000148346 ENSG00000163739 ENSG00000166136 ENSG00000165264 ENSG00000169245 ENSG00000136521 ENSG00000149968 ENSG00000157064 ENSG00000119013 ENSG00000173614 ENSG00000096717 ENSG00000136689 PMC3494243__F2 Pathways for C18 PUFA conversion to C20–22 PUFA synthesis ENSG00000134824 ENSG00000149485 PMC3680926__F1 Estrogen receptor functional domains and signal transduction schemes PMC3008616__F1 EGFR pathway and its main downstream effectors (top) ENSG00000157764 ENSG00000146648 PMC9250793__F1 Signaling pathways in hair follicle stem cells ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5535855__F3 Schematic diagram showing the pathological cardiac functions of ANKRD1 in relation to hypertrophy, fibrosis and apoptosis ENSG00000129038 ENSG00000285109 ENSG00000167779 ENSG00000164627 ENSG00000260428 ENSG00000122194 PMC7396149__F4 Immunosuppressive drugs for corneal transplantation and their sites of action in the immune system ENSG00000134982 ENSG00000163599 ENSG00000198793 ENSG00000062485 PMC9250793__F4 Signaling pathways in hair follicle stem cells ENSG00000106571 ENSG00000128602 PMC7769953__F1 IL-6 signaling pathway and inhibitory agents ENSG00000291971 ENSG00000168610 PMC5628484__F6 Regulatory roles of differentially expressed genes involved in the MAPK signaling pathway (a, map04010) and pathways in cancer (b, map05200) ENSG00000172680 ENSG00000130522 ENSG00000087842 ENSG00000130159 ENSG00000177084 ENSG00000175104 ENSG00000127191 ENSG00000146648 ENSG00000026103 PMC11048686__F1 Vitamin D synthesis pathway ENSG00000111012 ENSG00000105516 ENSG00000019186 ENSG00000186104 ENSG00000135929 PMC4383680__F10 G-protein independent coupling of the MC4R to Kir 7.1 in hypothalamic neurons ENSG00000115138 ENSG00000166603 PMC6314014__F2 Top network of metastasis virulence biomarkers (Ingenuity Pathway Analysis Knowledge Base) ENSG00000168329 ENSG00000152661 ENSG00000106333 ENSG00000105835 ENSG00000142798 ENSG00000116962 ENSG00000143387 ENSG00000104870 ENSG00000244486 ENSG00000129038 ENSG00000163430 ENSG00000106624 ENSG00000171621 PMC6314014__F1 Top network depicting the influence of high fat diet on mammary tumor gene expression (Ingenuity Pathway Analysis Knowledge Base) ENSG00000070756 ENSG00000134339 ENSG00000070193 ENSG00000141448 ENSG00000130700 ENSG00000108654 ENSG00000134871 ENSG00000164305 ENSG00000104408 ENSG00000089022 ENSG00000253729 PMC5350105__F1 M1 macrophage metabolism ENSG00000131473 ENSG00000065833 ENSG00000079432 ENSG00000084774 ENSG00000026103 PMC11484340__F3 Cross-inhibition between the PI3K/AKT/mTOR and RAF/MEK/ERK pathways ENSG00000002330 PMC3751038__F2 T-cell death during HIV-1 infection ENSG00000168040 ENSG00000121966 ENSG00000026103 PMC6523474__F2 Acute phase response (APR) is central to the FL induced response in skin, brain, and liver of all three model organisms ENSG00000122025 ENSG00000099985 ENSG00000242689 ENSG00000198793 ENSG00000105697 ENSG00000189403 ENSG00000130159 ENSG00000135605 ENSG00000127948 ENSG00000121966 PMC7981903__F3 Role of GRP78 in cellular apoptosis ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC3408740__F1 Alarmins: awaiting a clinical response ENSG00000143546 ENSG00000163220 ENSG00000125538 ENSG00000189403 PMC3700945__F5 Pathway detail for the IPN: Mucus Hypersecretion model.Notes: The Mucus Hypersecretion model contains signaling detail from four main pathways known to induce airway MUC5AC production ENSG00000185591 PMC4458296__F1 Purine metabolic pathway ENSG00000116748 ENSG00000196839 ENSG00000291814 ENSG00000158125 PMC4199871__F2 WNT Signaling in Bone Development and Homeostasis ENSG00000156076 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000168036 PMC5310224__F5 Unfolded protein response in immunity and inflammation ENSG00000162711 ENSG00000128272 ENSG00000125538 ENSG00000169136 ENSG00000265972 ENSG00000100219 PMC7266379__F1 Loss of MAP3K7 sensitizes prostate cancer cells to CDK1/2 inhibition and DNA damage by disrupting homologous recombination ENSG00000228716 ENSG00000100519 ENSG00000131462 ENSG00000178999 ENSG00000115350 ENSG00000108443 ENSG00000167965 ENSG00000131470 ENSG00000185010 ENSG00000183765 ENSG00000157184 ENSG00000138778 ENSG00000089685 ENSG00000148229 ENSG00000291814 ENSG00000136997 ENSG00000220205 ENSG00000014138 ENSG00000187531 ENSG00000142192 ENSG00000095059 ENSG00000131747 ENSG00000108423 ENSG00000213341 ENSG00000102967 ENSG00000134900 ENSG00000108179 ENSG00000138823 ENSG00000175899 ENSG00000100479 ENSG00000103707 ENSG00000291803 ENSG00000196591 ENSG00000116791 ENSG00000087586 ENSG00000135341 ENSG00000166851 ENSG00000110801 ENSG00000100714 ENSG00000263528 ENSG00000205155 ENSG00000123374 ENSG00000051180 ENSG00000017260 ENSG00000137714 ENSG00000177084 ENSG00000169567 ENSG00000106348 ENSG00000138160 ENSG00000284320 ENSG00000185627 ENSG00000135446 ENSG00000167325 ENSG00000292130 ENSG00000148702 ENSG00000171848 ENSG00000149554 ENSG00000116761 PMC4265444__F5 The sulfur assimilation pathway and the genes encoding the enzymes of the different biosynthetic steps ENSG00000087250 ENSG00000176153 PMC8918735__F8 Decoding the Role of Astrocytes in the Entorhinal Cortex in Alzheimer’s Disease Using High-Dimensional Single-Nucleus RNA Sequencing Data and Next-Generation Knowledge Discovery Methodologies: Focus on Drugs and Natural Product Remedies for Dementia ENSG00000002330 ENSG00000164949 ENSG00000026103 PMC6324535__F7 Working model ENSG00000135446 ENSG00000168036 ENSG00000105810 PMC8918735__F7 Decoding the Role of Astrocytes in the Entorhinal Cortex in Alzheimer’s Disease Using High-Dimensional Single-Nucleus RNA Sequencing Data and Next-Generation Knowledge Discovery Methodologies: Focus on Drugs and Natural Product Remedies for Dementia ENSG00000002330 ENSG00000164949 ENSG00000026103 PMC4422099__F2 Targeting TRAF3 Downstream Signaling Pathways in B cell Neoplasms ENSG00000143799 ENSG00000215021 ENSG00000171444 ENSG00000131323 PMC8918735__F4 Decoding the Role of Astrocytes in the Entorhinal Cortex in Alzheimer’s Disease Using High-Dimensional Single-Nucleus RNA Sequencing Data and Next-Generation Knowledge Discovery Methodologies: Focus on Drugs and Natural Product Remedies for Dementia ENSG00000149311 ENSG00000100084 ENSG00000142192 ENSG00000158104 ENSG00000127948 ENSG00000102977 PMC8918735__F3 Decoding the Role of Astrocytes in the Entorhinal Cortex in Alzheimer’s Disease Using High-Dimensional Single-Nucleus RNA Sequencing Data and Next-Generation Knowledge Discovery Methodologies: Focus on Drugs and Natural Product Remedies for Dementia ENSG00000133116 ENSG00000007908 PMC2586109__F1 Protein kinase C isozymes as therapeutic targets for treatment of human cancers ENSG00000134982 ENSG00000168036 PMC9091963__F1 Insights Into Vascular Anomalies, Cancer, and Fibroproliferative Conditions: The Role of Stem Cells and the Renin-Angiotensin System ENSG00000175054 ENSG00000168036 PMC5536362__F8 G protein-coupled receptor kinase 2 promotes cardiac hypertrophy PMC3578734__F1 Scheme of CML hematopoietic stem cell signaling pathways in which predicted targets of microRNAs associated with CML are involved ENSG00000033327 ENSG00000002330 ENSG00000110395 ENSG00000136997 PMC5458280__F3 Carboplatin-induced hematotoxicity among patients with non-small cell lung cancer: Analysis on clinical adverse events and drug-gene interactions ENSG00000177455 ENSG00000135218 ENSG00000075142 ENSG00000170458 ENSG00000104894 ENSG00000272398 ENSG00000164399 ENSG00000105656 ENSG00000026508 ENSG00000010278 ENSG00000187266 ENSG00000174059 PMC3539548__F1 Host cell machinery gets activated during influenza infection and leads to trigger Signaling pathways ENSG00000180210 ENSG00000144895 PMC9091963__F8 Insights Into Vascular Anomalies, Cancer, and Fibroproliferative Conditions: The Role of Stem Cells and the Renin-Angiotensin System ENSG00000168036 PMC4829957__F3 Targeting EPO and EPO RECEPTOR PATHWAYS in Anemia and Dysregulated Erythropoiesis ENSG00000178752 ENSG00000072135 ENSG00000187266 ENSG00000179295 PMC9091963__F9 Insights Into Vascular Anomalies, Cancer, and Fibroproliferative Conditions: The Role of Stem Cells and the Renin-Angiotensin System ENSG00000188404 PMC4327877__F8 TGF-Alpha-IL-1A/Beta-IL-1ra autocrine cascade contributes to TNF-induced hepatocyte proliferation and Adv-infection sensitized apoptosis through the regulation of multiple shared signaling pathways ENSG00000163235 ENSG00000146648 PMC7835526__F3 Interplay of IGF-1R-related signaling and niche microenvironment in stemness expressions of different cell types ENSG00000178860 ENSG00000113905 ENSG00000133937 ENSG00000198793 ENSG00000121966 ENSG00000140443 PMC4588066__F1 Regulation of oocyte maturation ENSG00000172680 ENSG00000134982 ENSG00000276876 PMC10985098__F3 Skeletal interoception in the aberrant subchondral bone remodeling of OA ENSG00000178860 ENSG00000198576 PMC3021995__F3 Post-transcriptional control of mammalian clock genes ENSG00000132326 ENSG00000138668 PMC8151534__F7 Evidence of Cooperation between Hippo Pathway and RAS Mutation in Thyroid Carcinomas ENSG00000110330 ENSG00000134982 ENSG00000109321 ENSG00000064393 ENSG00000168036 ENSG00000150457 ENSG00000081051 ENSG00000131023 ENSG00000140807 ENSG00000186575 ENSG00000089685 ENSG00000149269 ENSG00000136997 ENSG00000107551 ENSG00000169435 ENSG00000125968 PMC2680597__F1 Methylobacterium Genome Sequences: A Reference Blueprint to Investigate Microbial Metabolism of C1 Compounds from Natural and Industrial Sources ENSG00000261701 ENSG00000175198 ENSG00000114054 ENSG00000166278 PMC9106463__F3 PKM2 in the Regulation of Mitochondrial Function: Focus on Mitochondrial Metabolism, Oxidative Stress, Dynamic, and Apoptosis. PKM2 in Mitochondrial Function ENSG00000171791 PMC8336005__F4 Wnt Signaling: From Mesenchymal Cell Fate to Lipogenesis and Other Mature Adipocyte Functions ENSG00000111049 ENSG00000281324 ENSG00000116729 ENSG00000162337 ENSG00000174804 ENSG00000168036 ENSG00000106483 ENSG00000276920 ENSG00000104332 ENSG00000140807 ENSG00000110693 ENSG00000157240 ENSG00000171016 ENSG00000125398 ENSG00000120057 ENSG00000104290 ENSG00000102312 ENSG00000177283 PMC8336005__F3 Wnt Signaling: From Mesenchymal Cell Fate to Lipogenesis and Other Mature Adipocyte Functions ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000121058 ENSG00000168036 PMC8155968__F2 Redox Control in Acute Lymphoblastic Leukemia: From Physiology to Pathology and Therapeutic Opportunities ENSG00000198793 ENSG00000168685 PMC8155968__F1 Redox Control in Acute Lymphoblastic Leukemia: From Physiology to Pathology and Therapeutic Opportunities ENSG00000149311 ENSG00000175054 ENSG00000198793 ENSG00000171791 PMC9666367__F2 Cellular phenotypic transitions in diabetic nephropathy: An update ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000128602 ENSG00000077782 PMC12084448__F4 Metabolomics study in NENs ENSG00000121989 ENSG00000114739 PMC7882971__F6 LETM1 down‐regulation‐induced autophagy in CRC cells ENSG00000198793 ENSG00000168924 PMC4867331__F3 Notch and Wnt pathway inhibition by natural products ENSG00000283780 ENSG00000134982 ENSG00000136997 ENSG00000026508 PMC8226851__F4 SARS-CoV-2: One Year in the Pandemic. What Have We Learned, the New Vaccine Era and the Threat of SARS-CoV-2 Variants ENSG00000213928 ENSG00000130234 ENSG00000276561 ENSG00000164342 PMC12084448__F2 Lipid metabolism changes in NENs ENSG00000112972 ENSG00000036530 ENSG00000198793 ENSG00000169710 ENSG00000168036 ENSG00000073792 ENSG00000091542 PMC12084448__F1 Metabolic pathways in NENs ENSG00000131473 ENSG00000135218 ENSG00000042832 ENSG00000198793 ENSG00000169710 PMC3111669__F2 BMP signaling and its blocking ENSG00000170365 ENSG00000137834 PMC6536572__F3 Nrf2/ARE pathway during basal and stressed conditions ENSG00000181019 ENSG00000100387 PMC3750636__F1 USP1 Domain structure and summary of the cellular functions of the USP1/UAF1 complex ENSG00000144554 ENSG00000134982 ENSG00000132646 ENSG00000162607 ENSG00000070950 PMC7640403__F4 Amino acid, energy and Wnt signaling to mTORC1 ENSG00000177058 ENSG00000198793 ENSG00000052795 ENSG00000155792 ENSG00000274070 ENSG00000167965 ENSG00000239282 PMC9376771__F1 Hepatocellular carcinoma and microbiota: Implications for clinical management and treatment ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC7281579__F1 Increased glucose metabolism facilitates endometrial cancer phenotypes ENSG00000131473 ENSG00000147162 ENSG00000150907 ENSG00000198793 ENSG00000169710 ENSG00000177084 ENSG00000168610 ENSG00000159399 PMC2715501__F1 Study background ENSG00000086696 ENSG00000108786 ENSG00000179142 ENSG00000176387 PMC7489527__F6 Anti-neuroinflammatory effects of Clinacanthus nutans leaf extract on metabolism elucidated through 1H NMR in correlation with cytokines microarray ENSG00000111537 ENSG00000113520 PMC4747705__F6 BRAF(V600E)-directed recruitment of MAFG and its corepressors to CIMP and HIM gene promoters ENSG00000088305 ENSG00000100888 ENSG00000197063 ENSG00000156273 PMC3618314__F7 Characterization of CP genes in relation to the canonical TGFB signaling pathway ENSG00000113600 ENSG00000156574 PMC6614686__F5 Pathway Map of Glioblastoma obtained from Wikipathways using Cytoscape ENSG00000291971 ENSG00000169047 ENSG00000118971 ENSG00000137764 ENSG00000124762 ENSG00000010671 ENSG00000012048 ENSG00000163558 ENSG00000150907 ENSG00000166501 ENSG00000197943 ENSG00000123374 ENSG00000198670 ENSG00000105810 ENSG00000124181 ENSG00000139687 ENSG00000140443 ENSG00000196712 ENSG00000136158 ENSG00000027075 ENSG00000157764 ENSG00000065559 ENSG00000184481 ENSG00000149311 ENSG00000066468 ENSG00000110395 ENSG00000067606 ENSG00000134853 ENSG00000146648 PMC6928836__F1 A schematic illustration of unfolded protein response (UPR) and the effects of salicylic acid (SA) under stress condition in plants ENSG00000281857 ENSG00000062485 PMC6563011__F2 Schematic view of PKCA inhibitory activity on the Wnt/Beta-catenin signaling pathway in the normal colon epithelium and in colon cancer ENSG00000134982 ENSG00000173599 ENSG00000168036 ENSG00000078098 PMC3192911__F2 Therapeutic tol-DC in organ allotransplantationTol DC can be either recipient- or donor-derived (in the case of living-donor transplantation) ENSG00000134982 ENSG00000276051 ENSG00000049768 PMC7719100__F2 Molecular mechanism of adipogenesis ENSG00000170365 ENSG00000168036 PMC8336005__F5 Wnt Signaling: From Mesenchymal Cell Fate to Lipogenesis and Other Mature Adipocyte Functions ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000120057 ENSG00000183579 ENSG00000168036 ENSG00000146374 PMC8267940__F4 Instruction of Immunometabolism by Adipose Tissue: Implications for Cancer Progression ENSG00000198793 ENSG00000118520 ENSG00000026103 PMC6196292__F4 The proposed mechanisms of NEAT1 action in cancer ENSG00000168610 ENSG00000146648 PMC8801219__F8 Ecballium elaterium attenuates neuroinflammation in an animal model of Alzheimer’s disease through modulation of nuclear factor KB pathway ENSG00000102871 ENSG00000125538 ENSG00000172936 PMC7589120__F1 Pathway connecting lipid synthesis, lysosomes dysfunction and iron accumulation in NBIA syndromes ENSG00000184381 ENSG00000292221 ENSG00000131943 ENSG00000068120 ENSG00000115827 PMC6832112__F1 RTK and nRTK networks in H ENSG00000087245 ENSG00000100985 ENSG00000137845 ENSG00000168610 ENSG00000146648 PMC9385341__F2 From Iron Metabolism to Ferroptosis: Pathologic Changes in Coronary Heart Disease ENSG00000168003 ENSG00000167468 ENSG00000111684 PMC11466420__F8 Graphical overview of the effect of BA treatment on porcine oocyte maturation ENSG00000079999 PMC5609982__F10 Anti-proliferation of triple-negative breast cancer cells with physagulide P: ROS/JNK signaling pathway induces apoptosis and autophagic cell death ENSG00000134057 PMC4051344__F1A Regulation of Inflammation in Cancer by Eicosanoids ENSG00000226275 PMC3132189__F4 Proposed lipid metabolic pathways in Giardia ENSG00000173599 ENSG00000099864 ENSG00000184207 PMC4169646__F7 Prolyl-Hydroxylase Inhibitor, Ethyl-3,4-Dihydroxybenzoate, Induces Cell Autophagy and Apoptosis in Esophageal Squamous Cell Carcinoma Cells via Up-Regulation of BNIP3 and N-myc Downstream-Regulated Gene-1 ENSG00000171791 PMC3190890__F7 The signaling pathway of EpCAM complex proteins in the regulation and enhancement of OSKM-mediated pluripotency reprogramming ENSG00000143801 ENSG00000119888 ENSG00000288292 PMC4356243__F5 Advances in therapeutic development for spinal muscular atrophy ENSG00000273772 ENSG00000138798 ENSG00000146648 PMC4673535__F4 Profiles of microRNA networks in intestinal epithelial cells in a mouse model of colitis ENSG00000161921 ENSG00000138755 ENSG00000103375 ENSG00000118777 PMC4825819__F5 Coordinating muscle-specific gene expression with cell cycle exit ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000119125 PMC9448575__F3 Crosstalk between Oxidative Stress and Exosomes ENSG00000146648 PMC3375988__F7 Schematic representation of the proposed roles of oleosin ENSG00000173599 ENSG00000198670 PMC5410396__F2 Promiscuity of PLP enzymes involved in H2S synthesis PMC9202199__F9 Power of heteronemin in cancers ENSG00000002330 ENSG00000198793 ENSG00000168610 PMC9202199__F8 Power of heteronemin in cancers ENSG00000171791 ENSG00000168610 PMC9202199__F6 Power of heteronemin in cancers ENSG00000132646 ENSG00000168040 ENSG00000026103 PMC4532404__F7 Signaling pathway of focal adhesion ENSG00000169291 ENSG00000002330 ENSG00000010810 PMC7166610__F2 Illustration of virus activation of IFN‐I synthesis and its inhibition by the MERS‐CoV M, 4a, 4b and PLP proteins ENSG00000187608 ENSG00000131323 PMC9149322__F8 Illustration of the mechanism of EEZS-induced apoptosis in human bladder cancer T24 cells ENSG00000171791 ENSG00000026103 PMC4532404__F8 Signaling pathway of regulation of actin cytoskeleton ENSG00000180210 ENSG00000069482 ENSG00000134982 ENSG00000138443 ENSG00000163914 ENSG00000089159 PMC3825194__F1 TGFB signaling through Smad-dependent and Smad-independent pathways ENSG00000137834 ENSG00000163914 ENSG00000175104 PMC3825194__F4 TGFB signaling pathway inhibitors under development for potential cancer therapy PMC5956756__F7 Proposed mechanistic scheme: miR-29c suppresses breast cancer by the TIMP3/STAT1/FOXO1 pathway ENSG00000100234 ENSG00000115415 ENSG00000150907 PMC9579409__F5 Hepatic transcriptome profiling according to growth rate reveals acclimation in metabolic regulatory mechanisms to cyclic heat stress in broiler chickens ENSG00000142192 ENSG00000133116 ENSG00000148798 ENSG00000038002 ENSG00000119912 ENSG00000062485 PMC8417882__F5 Harnessing TRAIL-Induced Apoptosis Pathway for Cancer Immunotherapy and Associated Challenges ENSG00000128272 ENSG00000144895 ENSG00000162772 PMC5344005__F1 Molecular functions of long non-coding RNAs (lncRNAs) at different stages of prostate cancer, from prostate adenocarcinoma (A) to ongoing castration resistance (B) to a castration-resistant state (C) ENSG00000157554 ENSG00000123975 ENSG00000175793 ENSG00000173599 ENSG00000171940 ENSG00000106772 PMC8417882__F4 Harnessing TRAIL-Induced Apoptosis Pathway for Cancer Immunotherapy and Associated Challenges ENSG00000002330 ENSG00000198793 PMC4573218__F3 Some of the proposed signaling pathways activated by NK-R ENSG00000169291 ENSG00000291971 ENSG00000163914 PMC6770188__F5 Our model of the BRAF mutation positive mitogen-activated protein kinase (MAPK) pathway signaling mechanisms ENSG00000115904 ENSG00000196712 PMC6088794__F1 Androgen receptor signaling axis and potential androgen-dependent and independent mechanisms of disease progression ENSG00000198793 PMC8417882__F2 Harnessing TRAIL-Induced Apoptosis Pathway for Cancer Immunotherapy and Associated Challenges ENSG00000168040 PMC9579409__F3 Hepatic transcriptome profiling according to growth rate reveals acclimation in metabolic regulatory mechanisms to cyclic heat stress in broiler chickens ENSG00000151657 ENSG00000002330 PMC3314616__F2 Methamphetamine Causes Differential Alterations in Gene Expression and Patterns of Histone Acetylation/Hypoacetylation in the Rat Nucleus Accumbens ENSG00000023445 ENSG00000152266 ENSG00000005339 ENSG00000100906 ENSG00000130287 ENSG00000108551 ENSG00000134363 ENSG00000117152 ENSG00000137880 ENSG00000064300 ENSG00000007171 ENSG00000104368 ENSG00000103942 ENSG00000150782 ENSG00000111537 ENSG00000172216 ENSG00000084676 ENSG00000177606 ENSG00000175899 ENSG00000130222 ENSG00000185591 ENSG00000124253 ENSG00000154928 PMC4081601__F3 Proposed mechanisms of anticancer activity of digoxin ENSG00000291971 ENSG00000146648 PMC10252649__F1 mTOR Signaling Pathway in Bone Diseases Associated with Hyperglycemia ENSG00000177169 ENSG00000150907 ENSG00000106070 ENSG00000155792 ENSG00000112561 PMC9311581__F3 Metabolic Adaptation-Mediated Cancer Survival and Progression in Oxidative Stress ENSG00000125166 ENSG00000065833 ENSG00000197713 ENSG00000135218 ENSG00000181788 ENSG00000092621 ENSG00000135069 ENSG00000105953 ENSG00000159399 ENSG00000026103 PMC7696540__F4 Downstream signaling of EGFR and other receptor tyrosine kinases [,,] ENSG00000122025 ENSG00000198793 ENSG00000146648 PMC9311581__F2 Metabolic Adaptation-Mediated Cancer Survival and Progression in Oxidative Stress ENSG00000104856 ENSG00000012048 ENSG00000254986 ENSG00000138798 ENSG00000173039 ENSG00000083312 ENSG00000162073 ENSG00000079999 PMC11035635__F2 Core molecular mechanisms of different types of RCD and the potential CAF-derived molecules that regulate RCD ENSG00000278718 ENSG00000177169 ENSG00000019991 ENSG00000110497 ENSG00000150782 ENSG00000123395 ENSG00000107562 ENSG00000126775 ENSG00000167468 ENSG00000198793 ENSG00000189403 ENSG00000102967 PMC9503143__SF1 H2O2/DEM-Promoted Maft Promoter Demethylation Drives Nrf2/ARE Activation in Zebrafish ENSG00000181019 ENSG00000079999 PMC12122316__F4 LncRNAs play a ceRNA regulatory role in RA (by Figdraw) ENSG00000100811 ENSG00000132906 ENSG00000204262 ENSG00000136869 ENSG00000077463 ENSG00000163638 ENSG00000164305 ENSG00000175894 ENSG00000026103 PMC10138803__F7 MicroRNA-146b-5p Suppresses Pro-Inflammatory Mediator Synthesis via Targeting TRAF6, IRAK1, and RELA in Lipopolysaccharide-Stimulated Human Dental Pulp Cells ENSG00000115008 ENSG00000170458 ENSG00000125538 ENSG00000173039 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000168610 ENSG00000184216 ENSG00000116984 PMC9570224__F5 Targeting Phospholipase D Pharmacologically Prevents Phagocytic Function Loss of Retinal Pigment Epithelium Cells Exposed to High Glucose Levels ENSG00000129219 ENSG00000197713 ENSG00000173599 PMC12122316__F3 Major apoptosis signaling pathways participate in RA (by Figdraw) ENSG00000132906 ENSG00000087095 ENSG00000002330 ENSG00000102871 ENSG00000168036 ENSG00000168040 ENSG00000127191 ENSG00000164305 ENSG00000115317 ENSG00000149311 ENSG00000175054 ENSG00000177606 ENSG00000083799 PMC5826678__F2 Three basic mechanisms of aberrant activation of Hedgehog signaling ENSG00000128602 PMC5596586__F6 Diagram showing the mechanisms of CHAC2 ENSG00000128272 ENSG00000143942 PMC8229180__F2 AMPK/p27Kip1 Pathway as a Novel Target to Promote Autophagy and Resilience in Aged Cells ENSG00000177169 ENSG00000135446 ENSG00000198793 ENSG00000123374 PMC3709411__F1 Illustration of important relationships between metabolome, proteome, and genome in cancerous cells ENSG00000136997 PMC8229180__F1 AMPK/p27Kip1 Pathway as a Novel Target to Promote Autophagy and Resilience in Aged Cells ENSG00000145604 ENSG00000135446 ENSG00000123374 PMC6237070__F1 Treg suppression ENSG00000089692 ENSG00000134982 ENSG00000026103 PMC7464740__F1 General model for the Wnt/Beta-catenin signaling pathway and its regulation by the destruction complex ENSG00000281324 ENSG00000134982 ENSG00000168036 PMC7758070__F8 Proposed model of GGGGCC repeat expansion pathogenesis ENSG00000112561 ENSG00000147894 PMC7411263__F7 Genes targeted by DE miRNAs enriched in the downstream of p53 signaling pathway ENSG00000048392 ENSG00000105810 ENSG00000118971 PMC7411263__F6 Hypoxia-related signaling pathways enriched by target genes of DE miRNAs in different tissues, including (A) the HIF-1 signaling pathway in heart, and the insulin signaling pathway in (B) muscle and (C) liver ENSG00000141349 ENSG00000124102 ENSG00000140992 ENSG00000117020 ENSG00000148660 ENSG00000150907 ENSG00000111713 ENSG00000072274 ENSG00000102893 ENSG00000197943 ENSG00000124181 ENSG00000124253 PMC11302868__F2 Four main defense pathways in ferroptosis ENSG00000167468 ENSG00000102967 PMC9157004__F4 High Diversity of Glycosphingolipid Glycans of Colorectal Cancer Cell Lines Reflects the Cellular Differentiation Phenotype ENSG00000157557 ENSG00000064225 ENSG00000135100 ENSG00000176597 ENSG00000135454 ENSG00000111728 ENSG00000163132 ENSG00000183778 ENSG00000115525 ENSG00000113722 ENSG00000073849 ENSG00000100625 PMC4254557__F8 Descending Control of Itch Transmission by the Serotonergic System via 5-HT1A-Facilitated GRP-GRPR Signaling ENSG00000078747 PMC8613759__F7 CPEB1, a novel risk gene in recent-onset schizophrenia, contributes to mitochondrial complex I defect caused by a defective provirus ERVWE1 ENSG00000178127 PMC11693940__F8 CXCR2 activated JAK3/STAT3 signaling pathway exacerbating hepatotoxicity associated with tacrolimus ENSG00000081041 ENSG00000105639 ENSG00000168610 PMC9399134__F5 Classical epithelial-mesenchymal transition (EMT) and alternative cell death process-driven blebbishield metastatic-witch (BMW) pathways to cancer metastasis ENSG00000186847 ENSG00000122691 ENSG00000136997 ENSG00000085662 ENSG00000112715 PMC4276806__F2 Proposed pathogenic mechanisms of Alpha-syn-related Lewy body formation in PD ENSG00000158828 ENSG00000163295 PMC7706002__F2 DEGs PPI network complex ENSG00000145632 ENSG00000019991 ENSG00000164932 ENSG00000169071 ENSG00000088826 ENSG00000164251 ENSG00000163568 ENSG00000135678 ENSG00000164162 ENSG00000087303 ENSG00000112715 ENSG00000146733 ENSG00000101850 ENSG00000117525 ENSG00000198108 ENSG00000108821 ENSG00000156869 ENSG00000285023 ENSG00000147027 ENSG00000162520 ENSG00000008394 ENSG00000000971 ENSG00000151388 ENSG00000136603 ENSG00000117226 ENSG00000133110 ENSG00000185532 ENSG00000198846 ENSG00000156113 PMC7204122__F4 Knockdown of IL6 in human endothelial cells affects the gene expression of proteins known to be involved in IL6-mediated signaling ENSG00000168610 PMC4553397__F1 Intracellular mechanisms involved in the control of FGF21 production and action on the heart ENSG00000105550 ENSG00000096717 ENSG00000077782 PMC3118351__F10 Pathways by which BrdU impairs epithelial repair and induces persistent inflammation in the chronic NA injury model ENSG00000149311 ENSG00000175054 PMC7204122__F8 Merged network showing the interplay between IL6-mediated signaling and interaction, binding, and adhesion of endothelial cells ENSG00000157554 ENSG00000157404 ENSG00000107562 ENSG00000110799 ENSG00000170558 ENSG00000113140 ENSG00000110651 ENSG00000007908 ENSG00000121807 ENSG00000168610 ENSG00000132170 ENSG00000179295 ENSG00000136807 ENSG00000077150 ENSG00000011422 ENSG00000082175 ENSG00000128052 ENSG00000177606 ENSG00000136997 ENSG00000188404 ENSG00000026508 ENSG00000115232 ENSG00000146648 ENSG00000116977 PMC6274918__F2 Maternal Beta-Cell Adaptations in Pregnancy and Placental Signalling: Implications for Gestational Diabetes ENSG00000019991 ENSG00000138798 ENSG00000198793 ENSG00000187140 ENSG00000118971 ENSG00000146648 PMC3920129__F3 TLR ligands/DAMPs, cellular location, and signaling in the vasculature ENSG00000172936 ENSG00000150455 ENSG00000276561 PMC3024251__F6 Downregulation of miR-342 is associated with tamoxifen resistant breast tumors ENSG00000175054 ENSG00000115392 ENSG00000177084 PMC6423797__F4 Regulation of Acetyl-CoA production by Beta-oxidation of fatty acids in mitochondria and peroxisomes, and the interexchange of 2-oxodipate and 2-oxogluterate by SLC25A21 over the membrane of these organelles in cells ENSG00000175309 ENSG00000152952 ENSG00000113790 PMC4112529__F1 Pathway for CoQ biosynthesis in eukaryotes ENSG00000132423 ENSG00000119723 ENSG00000110871 ENSG00000173085 ENSG00000167186 PMC6423797__F2 Regulation of immune EP expression by Tumour necrosis factor (TNF) signalling after exposure of IPEC-J2 cells to micro algae extracts in the absence and presence of ETEC ENSG00000167207 ENSG00000100906 ENSG00000197721 ENSG00000102871 ENSG00000007908 ENSG00000168040 ENSG00000073756 ENSG00000164305 ENSG00000149968 ENSG00000078747 ENSG00000184371 ENSG00000168404 ENSG00000074410 ENSG00000026103 PMC7733318__F8 Proposed working model ENSG00000167772 PMC7940767__F2 Simplified overview of the cAMP/PKA/CREB pathway in the control of GH synthesis and secretion in somatotrophs ENSG00000159224 ENSG00000291972 PMC7699590__F2 Platelet-derived growth factorB (PDGFB)-activated pathways mediating vascular smooth muscle cell (VSMC) migration ENSG00000149269 ENSG00000198793 ENSG00000086991 ENSG00000132478 PMC4695187__F8 Antidiabetic compound 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from averrhoa carambola L., demonstrates significant antitumor potential against human breast cancer cells PMC3352961__F3 Brain, blood, and iron: Perspectives on the roles of erythrocytes and iron in neurodegeneration ENSG00000149269 ENSG00000197969 ENSG00000047597 PMC7017041__F4 PARylation is required for chromatin structural changes following DNA damage ENSG00000143799 ENSG00000188486 ENSG00000149311 ENSG00000169621 ENSG00000173575 ENSG00000291803 ENSG00000277258 ENSG00000112130 ENSG00000111642 PMC2740793__F2 TGFB signaling pathway ENSG00000105516 PMC1852210__F1 Diagram of folate and one-carbon metabolism in mammalian organisms ENSG00000228716 ENSG00000065911 ENSG00000136877 ENSG00000173638 ENSG00000137563 ENSG00000145020 ENSG00000116984 ENSG00000284320 ENSG00000100714 ENSG00000134827 ENSG00000136371 ENSG00000124275 ENSG00000185339 ENSG00000116761 PMC8804151__F1 Lessons from Injury: How Nerve Injury Studies Reveal Basic Biological Mechanisms and Therapeutic Opportunities for Peripheral Nerve Diseases ENSG00000122882 ENSG00000065833 ENSG00000124155 ENSG00000082212 PMC9519149__F2 Cholesterol biosynthesis pathway, the enzymes involved in the synthesis and the diseases associated with the defective enzymes ENSG00000001630 ENSG00000116133 ENSG00000172893 ENSG00000109929 PMC8899174__F7 STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/B‐catenin pathway via binding to Annexin A2 in osteoporosis ENSG00000182718 ENSG00000134982 ENSG00000162551 ENSG00000168036 ENSG00000010270 ENSG00000163295 PMC3826841__F1 Regulation of the G2/M transition in the yeast cell cycle ENSG00000136425 PMC7056924__F1 Metabolic adaptations to acute metabolic stresses in the tumor microenvironment changes central carbon metabolism flow and exposes vulnerabilities ENSG00000134086 ENSG00000135218 ENSG00000198793 ENSG00000110931 ENSG00000115419 ENSG00000084774 PMC2768486__F10 Possible mechanism by which BMPs and estrogen regulate GNRH production by GT1-7 cells ENSG00000138071 PMC7269868__F2 Diagram showing the ER biogenesis pathway for membrane/secreted proteins, highlighting proteins associated with cystic disease ENSG00000086848 ENSG00000008952 ENSG00000139133 ENSG00000088035 ENSG00000214160 PMC4763967__F1 MiRNAs biogenesis pathway ENSG00000092847 ENSG00000134698 ENSG00000123908 ENSG00000132341 PMC5732723__F4 Characteristic proteins in the plasma of postoperative colorectal and liver cancer patients with Yin deficiency of liver-kidney syndrome ENSG00000039537 ENSG00000003436 ENSG00000113600 ENSG00000110799 ENSG00000181104 ENSG00000244731 ENSG00000010278 ENSG00000088926 ENSG00000166278 ENSG00000115718 ENSG00000178726 ENSG00000117322 ENSG00000185010 ENSG00000104368 ENSG00000180210 ENSG00000126218 ENSG00000101981 ENSG00000117525 ENSG00000011422 ENSG00000057593 ENSG00000175899 ENSG00000080618 ENSG00000062485 PMC9878249__F6 SARS‐CoV‐2 modulation of RIG‐I‐MAVS signaling: Potential mechanisms of impairment on host antiviral immunity and therapeutic approaches ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000276561 PMC3529762__F11 Illustration of GnRH signaling pathways necessary for FSHB induction PMC7232018__F1 Schematic view of the role of lysosomes in the autophagy pathway ENSG00000112367 ENSG00000123240 ENSG00000170266 ENSG00000198793 ENSG00000112561 ENSG00000182220 ENSG00000111670 PMC3392049__F3 An example pathway ENSG00000138795 ENSG00000171791 ENSG00000139687 PMC4061530__F1 Schematic representation of the ribonuclease activity of IRE1 and RNaseL showing cross-talk between the paths catalysed by the enzymes ENSG00000100219 ENSG00000135828 PMC11351413__F2 Biosynthetic pathway of cordycepin ENSG00000156110 ENSG00000196839 ENSG00000185129 ENSG00000146676 PMC6102368__F3 Crosstalk between Notch and tumor necrosis factor A (TNFA) in the tumor environment ENSG00000172680 ENSG00000125538 ENSG00000133961 ENSG00000114315 PMC8004153__F1 TGFB signalling is triggered through BMP or TGFB ligands ENSG00000170365 ENSG00000137834 ENSG00000198742 PMC6102368__F2 Interplay between IL-6 and Notch affects the anticancer immune response ENSG00000113520 ENSG00000168610 PMC8004153__F4 The TGFB signalling pathway by miRNAs PMC8004153__F3 Hypothetical scheme illustrating TGFB/EMT signalling in SS ENSG00000111537 PMC2293084__F8 PARP-1 in NFAT signaling pathway ENSG00000167720 ENSG00000285485 ENSG00000227345 PMC2796172__F2 Temporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and Bioenergetics ENSG00000125166 ENSG00000262785 ENSG00000114771 ENSG00000042832 ENSG00000162433 ENSG00000138029 ENSG00000169710 ENSG00000131828 ENSG00000127884 ENSG00000178814 ENSG00000067064 ENSG00000117054 ENSG00000074800 ENSG00000109084 ENSG00000173599 ENSG00000161533 ENSG00000146701 ENSG00000115419 ENSG00000104325 ENSG00000062485 PMC3962152__F4 KEGG Pathway database map showing Notch signaling including proteolytic cleavage and translocation of Notch followed by transcriptional activation of Notch target genes ENSG00000273529 ENSG00000133961 ENSG00000114315 PMC9253751__F9 Pre‐ and post‐conditioning with poly I:C exerts neuroprotective effect against cerebral ischemia injury in animal models: A systematic review and meta‐analysis ENSG00000183735 ENSG00000239732 ENSG00000172936 ENSG00000175104 ENSG00000276561 PMC9161009__F8 The unique telomere protection mechanism in ES cells ENSG00000149311 ENSG00000175054 ENSG00000180532 PMC3286890__F1 Wnt/Beta-catenin signalling and Beta-catenin role in adhesion in glioma cells ENSG00000134982 ENSG00000138798 ENSG00000168036 ENSG00000146648 PMC6433075__F10 Proposed model of glycogen phosphorylase regulation by epidermal growth factor receptor in human Kit 225 T cells ENSG00000146648 PMC9878249__F4 SARS‐CoV‐2 modulation of RIG‐I‐MAVS signaling: Potential mechanisms of impairment on host antiviral immunity and therapeutic approaches ENSG00000183735 ENSG00000088888 ENSG00000131323 PMC9878249__F3 SARS‐CoV‐2 modulation of RIG‐I‐MAVS signaling: Potential mechanisms of impairment on host antiviral immunity and therapeutic approaches ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000276561 PMC8843880__F6 Tumor microenvironment pathways: Cross regulation in breast cancer metastasis ENSG00000125398 ENSG00000148400 ENSG00000136997 ENSG00000026508 ENSG00000168036 ENSG00000100985 PMC9399134__F1 Classical epithelial-mesenchymal transition (EMT) and alternative cell death process-driven blebbishield metastatic-witch (BMW) pathways to cancer metastasis ENSG00000026508 PMC7957022__F3 CAFs drive resistance-related paracrine pathways in the TME ENSG00000159167 ENSG00000019991 ENSG00000125538 ENSG00000123191 ENSG00000164690 ENSG00000168610 PMC9399134__F2 Classical epithelial-mesenchymal transition (EMT) and alternative cell death process-driven blebbishield metastatic-witch (BMW) pathways to cancer metastasis ENSG00000149311 ENSG00000175054 ENSG00000070831 ENSG00000136997 ENSG00000189403 PMC7957022__F5 Main signaling pathways responsible for therapeutic resistance mediated by the tumor environment ENSG00000198793 ENSG00000175104 ENSG00000168610 PMC5020319__F3 De novo sequencing, assembly and analysis of eight different transcriptomes from the Malayan pangolin ENSG00000124102 PMC4813194__F2 The intrinsic apoptotic pathway is triggered by various stimuli inducing mitochondrial membrane permeabilization ENSG00000102871 ENSG00000168040 PMC9142561__F9 Early molecular events leading to COFILIN phosphorylation during mouse sperm capacitation are essential for acrosomal exocytosis ENSG00000106683 ENSG00000084112 PMC3201973__F9 Toll-like Receptor 3 Regulates Neural Stem Cell Proliferation by Modulating the Sonic Hedgehog Pathway ENSG00000164690 ENSG00000128602 ENSG00000164342 ENSG00000026103 PMC3531712__F1 p62-interacting partners and functions ENSG00000198793 ENSG00000175104 ENSG00000079999 PMC2645343__F2A Drug development against metastasis-related genes and their pathways: A rationale for cancer therapy ENSG00000019991 ENSG00000168036 ENSG00000122194 PMC9478949__F10 Alternative splicing of Arabidopsis G6PD5 recruits NADPH-producing OPPP reactions to the endoplasmic reticulum ENSG00000175054 ENSG00000166123 ENSG00000026103 PMC1919358__F5 WNT signalling KEGG pathway consisting of three subpathways with the genes on the microarray encircled (A) and expression profiles of genes during porcine myogenesis (B) ENSG00000071564 ENSG00000168036 PMC2690004__F3 Metabolic reconstruction of H ENSG00000182511 ENSG00000134982 ENSG00000150787 PMC6712555__F2 Vascular inflammation during tumor cell extravasation and metastasis ENSG00000108691 ENSG00000011132 ENSG00000125538 ENSG00000100985 ENSG00000112715 ENSG00000162692 ENSG00000121807 ENSG00000117322 PMC2775948__F2 Integrated Proteomic Analysis of Human Cancer Cells and Plasma from Tumor Bearing Mice for Ovarian Cancer Biomarker Discovery ENSG00000148346 ENSG00000092445 ENSG00000198053 ENSG00000105329 ENSG00000113504 ENSG00000163568 ENSG00000077984 ENSG00000169710 ENSG00000132478 ENSG00000216490 ENSG00000161055 ENSG00000137801 ENSG00000184500 ENSG00000162139 ENSG00000153208 ENSG00000163430 ENSG00000197594 ENSG00000187210 ENSG00000023572 ENSG00000137055 PMC9459699__F7 Different Effects of Low Selenite and Selenium-Nanoparticle Supplementation on Adipose Tissue Function and Insulin Secretion in Adolescent Male Rats ENSG00000148346 ENSG00000169047 ENSG00000250722 PMC6888337__F11 Canonical pathway explaining the NASH progression from steatosis to hepatocellular carcinoma ENSG00000166819 ENSG00000142192 ENSG00000100344 ENSG00000134824 ENSG00000149485 ENSG00000169710 ENSG00000099194 ENSG00000135587 PMC5831833__F1 Schematic overview of the autophagy pathway and target points of its modulators ENSG00000083290 ENSG00000126775 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC8320331__F2 Epigenetic Mechanisms Involved in HCV-Induced Hepatocellular Carcinoma (HCC) ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000120875 ENSG00000006283 ENSG00000168036 ENSG00000026103 PMC6073924__F5 Biomaterials in Tendon and Skeletal Muscle Tissue Engineering: Current Trends and Challenges ENSG00000019991 PMC4046519__F4 Network analysis performed on converging genes differentially regulated in response to different stresses in mouse and between different selected Flinders lines ENSG00000105894 ENSG00000100234 ENSG00000261456 ENSG00000066629 ENSG00000182670 ENSG00000140795 ENSG00000198576 ENSG00000027644 ENSG00000220205 ENSG00000137267 ENSG00000137941 PMC11978951__F5 Molecular interactions and downstream effects of the HIF-1 signalling pathway ENSG00000072274 ENSG00000080823 PMC12066067__F6 Samples for metagenomic analysis based on part of the basal metabolic pathways from the KEGG database ENSG00000131473 ENSG00000073578 ENSG00000105402 PMC3158739__F1 Ingenuity pathway analysis (IPA) of CDF driven pathway changes in BxPC-3 cells ENSG00000109854 ENSG00000113140 ENSG00000136997 ENSG00000291748 ENSG00000168036 ENSG00000291501 ENSG00000118777 PMC7269823__F3 Changes in extracellular matrix (ECM), focal adhesions, and integrin signaling in ADPKD ENSG00000049323 ENSG00000157764 ENSG00000198793 PMC8505796__F1 Aldehyde dehydrogenase 1A1 and 1A3 isoforms – mechanism of activation and regulation in cancer PMC5811049__F7 dWnt4 switches Beta-catenin dependence during oogenesis ENSG00000070831 ENSG00000168036 PMC11534180__F6 GABAergic synapse pathway modified from the KEGG database [29] ENSG00000115419 PMC11978951__F4 Astragaloside A against lung adenocarcinoma based on network pharmacology combined with molecular dynamics simulation technique ENSG00000087245 ENSG00000005339 ENSG00000116044 ENSG00000109320 ENSG00000291971 ENSG00000198793 ENSG00000150093 ENSG00000213341 ENSG00000112715 ENSG00000121879 ENSG00000168610 ENSG00000179295 ENSG00000135446 ENSG00000134853 ENSG00000123374 ENSG00000136869 ENSG00000001626 ENSG00000146648 PMC7305134__F5 TIE and the canonical TGFB signaling pathway regulated by ncRNAs ENSG00000111537 ENSG00000198742 ENSG00000049768 PMC11534180__F5 Synaptic vesicle cycle pathway modified from the KEGG database [29] ENSG00000132639 PMC7305134__F4 TIE and immune checkpoint molecules regulated by ncRNAs ENSG00000291603 ENSG00000134982 ENSG00000198793 PMC7305134__F3 TIE-associated stem cell signaling pathways by ncRNAs ENSG00000134982 ENSG00000168036 ENSG00000128602 PMC1751493__F2 In normal prostate epithelial cells (a), TGFB binds to the TBRI and TBRII receptors, activating the SMAD signalling pathway and inducing the transcription of IGFBP-3 and other regulatory genes ENSG00000124102 PMC5412347__F7 The VEGF/VEGFR/HIF-1A signaling pathway and the effects of melatonin treatment leading to the activation or repression of downstream molecules in OC cell ENSG00000065833 ENSG00000105329 PMC2972203__F8 Reverse-Phase Phosphoproteome Analysis of Signaling Pathways Induced by Rift Valley Fever Virus in Human Small Airway Epithelial Cells ENSG00000002330 ENSG00000115415 ENSG00000169047 ENSG00000168610 PMC5938400__F1 Mechanism of action of pharmacologic therapies ENSG00000198517 ENSG00000146648 PMC8505796__F3 Aldehyde dehydrogenase 1A1 and 1A3 isoforms – mechanism of activation and regulation in cancer ENSG00000184254 ENSG00000019991 ENSG00000198793 ENSG00000185591 ENSG00000168610 ENSG00000196712 PMC8505796__F2 Aldehyde dehydrogenase 1A1 and 1A3 isoforms – mechanism of activation and regulation in cancer ENSG00000168036 PMC8505796__F5 Aldehyde dehydrogenase 1A1 and 1A3 isoforms – mechanism of activation and regulation in cancer ENSG00000168283 ENSG00000117650 ENSG00000123374 ENSG00000283100 PMC4664161__F4 TLR4 and TLR3 sensitization ENSG00000172005 ENSG00000132478 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000276561 ENSG00000164342 PMC5437015__F8 Canonical Pathway of ‘Molecular Mechanisms of Cancer’ (IPA, p-value 0.0199) ENSG00000138795 ENSG00000002330 ENSG00000291971 ENSG00000064393 ENSG00000171791 ENSG00000168040 ENSG00000149311 ENSG00000012048 ENSG00000110395 ENSG00000144554 ENSG00000010810 ENSG00000163914 ENSG00000136997 ENSG00000150907 ENSG00000102104 ENSG00000080839 ENSG00000196712 PMC3419258__F6 Proposed model of FGF23 signaling in proximal tubular cells ENSG00000118972 ENSG00000152266 ENSG00000118515 ENSG00000077782 PMC5492501__F4 Myristoylation in regulating Fas/Fas ligand pathway during cytotoxic T cells activation: binding of a death ligand to Fas receptor leads to the formation of death-inducing signaling complex (DISC) ENSG00000002330 ENSG00000168040 ENSG00000136448 ENSG00000152465 ENSG00000026103 PMC5492501__F3 N-myristoyltransferase functions during T cell activation ENSG00000291603 ENSG00000213658 ENSG00000134982 ENSG00000156026 ENSG00000124181 PMC11497461__F1 Graphical representation of imatinib metabolism and transport ENSG00000138115 ENSG00000157404 ENSG00000165841 ENSG00000175003 ENSG00000186716 ENSG00000140505 ENSG00000140465 ENSG00000118777 PMC8697849__F6 Combined Oral Contraceptives and Venous Thromboembolism: Review and Perspective to Mitigate the Risk ENSG00000291971 PMC3424007__F1 Biological association network (BAN) of differentially expressed genes in common between CA and ICC ENSG00000090534 ENSG00000112964 ENSG00000156642 ENSG00000117400 ENSG00000006451 ENSG00000115350 ENSG00000145777 ENSG00000196498 ENSG00000196365 ENSG00000187266 PMC5372717__F4 Localization of Moco biosynthesis, FeS cluster biosynthesis and tRNA thiolation in humans ENSG00000182511 ENSG00000124217 ENSG00000167118 ENSG00000142544 PMC6514876__F10 Model outlining biomarkers and pathways between CTCs and PMN-MDSCs interactions (CTC/PMN-MDSC cluster) isolated from blood of metastatic cancer patients ENSG00000148400 ENSG00000241186 ENSG00000156574 PMC7226524__F2 Methionine metabolism ENSG00000151224 PMC7518341__F1 Angiotensin-converting enzyme 2 (ACE2) causes the production of angiotensin (1-7) Ang-(1-7) from angiotensin-2 (AngII) ENSG00000175054 ENSG00000130234 ENSG00000142224 PMC5689704__F5 Screening circular RNA expression patterns following focal cerebral ischemia in mice ENSG00000126016 ENSG00000110330 ENSG00000134982 ENSG00000109321 ENSG00000168036 ENSG00000150457 ENSG00000081051 ENSG00000132849 ENSG00000131023 ENSG00000140807 ENSG00000089685 ENSG00000136997 ENSG00000169435 ENSG00000125968 PMC6071262__F6 Schematic drawing of the 1-carbon methylation cycle PMC5586504__F1 Regulation of Wnt Signaling by Protocadherins ENSG00000087095 ENSG00000281324 ENSG00000162337 ENSG00000070831 ENSG00000100592 ENSG00000134982 ENSG00000168036 PMC8703161__F4 Gut-Liver Axis in Health and Disease: The Role of Gut Microbiota-Derived Signals in Liver Injury and Regeneration ENSG00000161921 PMC11604295__F2 Functions of TDEVs in tumor progression ENSG00000178860 ENSG00000067057 ENSG00000196839 ENSG00000146648 ENSG00000159399 PMC9367256__F2 Hallmarks of Cancer Applied to Oral and Oropharyngeal Carcinogenesis: A Scoping Review of the Evidence Gaps Found in Published Systematic Reviews ENSG00000138798 ENSG00000198793 PMC4662481__F7 Protein phosphatase PHLPP induces cell apoptosis and exerts anticancer activity by inhibiting Survivin phosphorylation and nuclear export in gallbladder cancer ENSG00000136997 PMC2679155__F1 Integrin-RTK signaling ENSG00000071051 PMC5064990__F3 KEGG pathway for insulin signaling ENSG00000171105 ENSG00000002330 ENSG00000198793 PMC8062415__F7 Hub genes associated with Interleukin-3-mediated signaling pathway ENSG00000114315 ENSG00000116183 ENSG00000137801 PMC8454558__F5 Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors ENSG00000019991 ENSG00000291971 ENSG00000178999 ENSG00000135446 ENSG00000138798 ENSG00000198793 ENSG00000087586 ENSG00000166851 ENSG00000099942 PMC5363569__F8 Estrogen related receptor alpha in castration-resistant prostate cancer cells promotes tumor progression in bone ENSG00000105329 ENSG00000133110 ENSG00000168016 ENSG00000112715 PMC6478727__F2 Differentially expressed coat color genes in Changthangi Pashmina goat and their involvement in melanogenesis signaling pathway (Adapted from ref.) ENSG00000168036 ENSG00000080166 ENSG00000107165 PMC3640511__F3 PRR activated signaling and antiviral responses during virus infection ENSG00000162711 ENSG00000140968 ENSG00000163568 ENSG00000163565 ENSG00000185745 ENSG00000168036 ENSG00000125347 ENSG00000276561 ENSG00000169245 ENSG00000239732 ENSG00000088888 ENSG00000125538 ENSG00000136869 ENSG00000168310 ENSG00000164342 PMC8073242__F6 Glutathionylation chemistry promotes interleukin-1 beta-mediated glycolytic reprogramming and pro-inflammatory signaling in lung epithelial cells ENSG00000173221 ENSG00000074800 ENSG00000141086 ENSG00000125538 PMC8073242__F4 Glutathionylation chemistry promotes interleukin-1 beta-mediated glycolytic reprogramming and pro-inflammatory signaling in lung epithelial cells ENSG00000173221 ENSG00000074800 ENSG00000141086 ENSG00000125538 PMC3702291__F7 Schematic model of signaling pathways in salinomycin-induced cell growth inhibition and apoptosis ENSG00000145604 ENSG00000002330 ENSG00000134982 ENSG00000123374 ENSG00000168610 PMC8241721__F2 Heme oxygenase 1: a novel oncogene in multiple gynecological cancers ENSG00000079999 PMC5868594__F2 MicroRNAs in the nuclear factor kappa B signaling pathways ENSG00000104856 ENSG00000102871 ENSG00000082512 ENSG00000172936 ENSG00000131323 ENSG00000127191 PMC5868594__F1 Nuclear factor kappa B and its activation mechanisms ENSG00000104856 ENSG00000173039 PMC2796989__F1 Interleukin (IL)-13/transforming growth factor (TGF)B signalling pathways ENSG00000123496 ENSG00000131724 PMC9317121__F12 BMP Signaling Pathway in Dentin Development and Diseases ENSG00000170365 ENSG00000164093 PMC9317121__F11 BMP Signaling Pathway in Dentin Development and Diseases ENSG00000120149 ENSG00000152785 ENSG00000152592 ENSG00000152591 ENSG00000163132 PMC3580410__F4 Functional interaction sub-network constructed by using module 2 genes ENSG00000138778 ENSG00000277909 ENSG00000163516 ENSG00000156970 ENSG00000109805 ENSG00000112984 ENSG00000291964 ENSG00000037474 ENSG00000105146 ENSG00000086827 ENSG00000138092 PMC9317121__F10 BMP Signaling Pathway in Dentin Development and Diseases ENSG00000170365 ENSG00000137834 ENSG00000120149 ENSG00000152785 ENSG00000152592 ENSG00000152591 ENSG00000163132 PMC8161962__F5 Persistent Newcastle disease virus infection in bladder cancer cells is associated with putative pro-survival and anti-viral transcriptomic changes ENSG00000136158 ENSG00000081181 ENSG00000152661 ENSG00000138795 ENSG00000204335 ENSG00000261857 ENSG00000170558 ENSG00000163083 ENSG00000124766 ENSG00000090776 ENSG00000196562 ENSG00000103888 ENSG00000140807 ENSG00000109854 ENSG00000131730 ENSG00000168646 ENSG00000167755 ENSG00000184304 ENSG00000115419 PMC3140915__F1 Simplified schematic of the Wnt/Beta-catenin signaling pathway ENSG00000134982 ENSG00000168036 PMC7716749__F1 Schematic diagram showing chondrocyte stages in the growth plate during development and selected signals that regulate these processes, including PTHrP, IHH, WNTs, FGFs, BMP and TGFB, IGF1 and IGF2 ENSG00000163501 PMC9272757__F2 Bacillus subtilis Produces Amino Acids to Stimulate Protein Synthesis in Ruminal Tissue Explants via the Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Beta–Serine/Threonine Kinase–Mammalian Target of Rapamycin Complex 1 Pathway ENSG00000198793 ENSG00000155792 ENSG00000167965 PMC6798084__F1 Nicotinamide adenine dinucleotide (NAD+) metabolism in plant cells ENSG00000008130 ENSG00000089159 PMC4585666__F1 Combination of transcriptomic and metabolomic analyses reveals a JAZ repressor in the jasmonate signaling pathway of Salvia miltiorrhiza ENSG00000136997 ENSG00000145020 ENSG00000084774 PMC5924972__F1 Saikosaponins and implications for age-related diseases ENSG00000162711 ENSG00000142082 ENSG00000138385 PMC8396502__F3 Liquid Biopsy for Cancer Cachexia: Focus on Muscle-Derived microRNAs ENSG00000100811 ENSG00000198793 ENSG00000096088 ENSG00000140443 PMC5489427__F2 Purinergic signaling in microglia in the pathogenesis of neuropathic pain ENSG00000108691 ENSG00000140968 ENSG00000121807 PMC3688534__F10 Distinct and Atypical Intrinsic and Extrinsic Cell Death Pathways between Photoreceptor Cell Types upon Specific Ablation of Ranbp2 in Cone Photoreceptors ENSG00000245848 ENSG00000105392 ENSG00000102076 ENSG00000101445 ENSG00000172244 ENSG00000168724 ENSG00000197386 ENSG00000185591 ENSG00000134245 ENSG00000260916 PMC8421236__F2 Daily Rice Bran Consumption for 6 Months Influences Serum Glucagon-Like Peptide 2 and Metabolite Profiles without Differences in Trace Elements and Heavy Metals in Weaning Nicaraguan Infants at 12 Months of Age ENSG00000173599 ENSG00000112186 PMC6796064__F1 Conceptualized overview of the association between inflammation and angiogenesis ENSG00000173821 ENSG00000019991 ENSG00000111537 ENSG00000168036 PMC7836022__F1 Metabolic pathways and signaling in cancer ENSG00000122966 ENSG00000136997 ENSG00000172005 PMC6335683__F1 Crosstalk between hepatocytes, hepatic nonparenchymal cells, and ncRNA during the pathology of NAFLD ENSG00000135218 ENSG00000042832 ENSG00000168610 ENSG00000125084 PMC3598852__F3 Digital Gene Expression Tag Profiling Analysis of the Gene Expression Patterns Regulating the Early Stage of Mouse Spermatogenesis ENSG00000169291 ENSG00000002330 ENSG00000177606 PMC5302955__F6 IGF-1R inhibition sensitizes breast cancer cells to ATM-related kinase (ATR) inhibitor and cisplatin ENSG00000175054 ENSG00000169047 ENSG00000140443 PMC7716145__F3 LPS-producing bacteria interact with TLRs through the NFKB signaling pathway ENSG00000150782 ENSG00000172936 ENSG00000127191 ENSG00000076604 PMC3598852__F5 Digital Gene Expression Tag Profiling Analysis of the Gene Expression Patterns Regulating the Early Stage of Mouse Spermatogenesis ENSG00000087095 ENSG00000147862 ENSG00000170458 ENSG00000138798 ENSG00000130159 ENSG00000026103 PMC3598852__F4 Digital Gene Expression Tag Profiling Analysis of the Gene Expression Patterns Regulating the Early Stage of Mouse Spermatogenesis ENSG00000087095 ENSG00000100592 ENSG00000134982 ENSG00000147869 ENSG00000113558 ENSG00000148175 ENSG00000196470 ENSG00000115718 PMC5648141__F1 Inferring gene and protein interactions using PubMed citations and consensus Bayesian networks ENSG00000198793 ENSG00000137193 PMC6976991__F4 Cytochrome P450 endoplasmic reticulum-associated degradation (ERAD): therapeutic and pathophysiological implications ENSG00000117525 ENSG00000171105 ENSG00000130649 ENSG00000087085 ENSG00000159346 PMC4580963__F1 Overview of Cr metabolism and the methionine cycle ENSG00000291507 PMC4491686__F3 Intracellular calcium and cell survival: Intracellular calcium activates the intermediate proteins in the signalling pathways in neuroblastoma ENSG00000002330 ENSG00000138798 ENSG00000036828 ENSG00000146648 PMC5039077__F23 Overview of the GO-induced cytokine response and autophagy mediated by the TLR4/TLR9 signaling pathway ENSG00000239732 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC4124053__F2 Apoptosis and the FLIP and NF-kappa B proteins as pharmacodynamic criteria for biosimilar TNF-alpha antagonists PMC5943909__F1 Summary of the proposed mechanisms involved in the regulation of gene expression by PNX in mHypoA-GnRH/GFP and mHypoA-Kiss/GFP-3 cell models ENSG00000184194 ENSG00000109163 ENSG00000170498 PMC4669553__F3 PLD–PA involvement in lipid metabolism and signalling and impact on SA biosynthesis and signalling in plant defence ENSG00000261701 ENSG00000173599 ENSG00000136997 ENSG00000198670 ENSG00000115419 PMC4895251__F3 Proposed model depicts that canonical Notch signaling augments the expression of Klf4/5, resulting in conjunctival goblet cell differentiation by down-regulating proliferation and up-regulating transcription of Muc 5/ac in conjunctival epithelium ENSG00000291363 ENSG00000136826 PMC6900666__F7 mTOR signalling pathway identified by KEGG analysis of the target genes of the DElncRNA ENSG00000101407 ENSG00000033327 ENSG00000198793 ENSG00000163914 ENSG00000155792 ENSG00000164327 ENSG00000176641 ENSG00000285069 PMC6900666__F6 CAM signalling pathway identified by KEGG analysis of the target genes of the DElncRNA ENSG00000149564 ENSG00000135218 ENSG00000169896 ENSG00000081237 ENSG00000134982 ENSG00000197471 ENSG00000179242 ENSG00000163599 ENSG00000170558 ENSG00000173482 ENSG00000150093 ENSG00000091409 ENSG00000007908 ENSG00000150637 ENSG00000292348 ENSG00000181847 ENSG00000188404 ENSG00000158887 ENSG00000165376 ENSG00000158825 ENSG00000154721 ENSG00000174059 PMC7401253__F5 Scheme highlighting the pathophysiology of neurodegenerative disorders and post-ischemic consequences along with indicating the underlying mechanism of neuroprotective action of algal compounds ENSG00000087085 PMC3907011__F5 Schematic diagram of the Bcl-w-induced signaling pathway by the activation of Sp1 ENSG00000185591 PMC9230675__F6 Difluoromethylornithine (DFMO) Enhances the Cytotoxicity of PARP Inhibition in Ovarian Cancer Cells ENSG00000143799 ENSG00000149311 ENSG00000012048 ENSG00000051180 ENSG00000139618 PMC6406872__F3 Structural hotspots and signaling pathways that are essential to the hepatic phenotype of highly differentiated HepaRG cells ENSG00000019991 ENSG00000142798 ENSG00000070831 ENSG00000105699 ENSG00000154639 ENSG00000072274 ENSG00000170558 ENSG00000168036 ENSG00000168615 ENSG00000092820 ENSG00000166147 ENSG00000104870 ENSG00000116161 ENSG00000148498 ENSG00000163558 ENSG00000163914 ENSG00000113558 ENSG00000136153 ENSG00000185591 ENSG00000026103 ENSG00000164342 ENSG00000003056 ENSG00000087095 ENSG00000143549 ENSG00000177663 ENSG00000137221 ENSG00000143375 ENSG00000148943 ENSG00000196411 ENSG00000100387 ENSG00000063660 ENSG00000146648 PMC3494149__F6 VANTED integrated pathway map of quantitative regulation of metabolites and enzymes of primary metabolism under nitrogen limitation in Chlamydomonas reinhardtii ENSG00000159224 ENSG00000122966 ENSG00000172005 ENSG00000188690 ENSG00000099864 ENSG00000146701 PMC5515036__F1 Biosynthetic pathway of cysteinyl leukotrienes (cysLTs) and cross regulation of their receptors ENSG00000226275 PMC5811677__F3 Key signaling pathways affected by CD5 expression ENSG00000110448 ENSG00000115415 ENSG00000198793 ENSG00000168610 ENSG00000141968 PMC12240740__F3 Network pharmacology results ENSG00000284774 ENSG00000169710 ENSG00000171791 ENSG00000124762 ENSG00000178726 ENSG00000183765 ENSG00000082175 ENSG00000136997 ENSG00000139687 ENSG00000276996 ENSG00000282899 ENSG00000087245 ENSG00000131747 ENSG00000213341 ENSG00000007908 ENSG00000125347 ENSG00000132693 ENSG00000007171 ENSG00000132170 ENSG00000169245 ENSG00000118785 ENSG00000102245 ENSG00000132646 ENSG00000026508 ENSG00000146648 ENSG00000169248 ENSG00000138798 ENSG00000140505 ENSG00000113161 ENSG00000158517 ENSG00000148344 ENSG00000112715 ENSG00000164305 ENSG00000118777 ENSG00000106546 ENSG00000104368 ENSG00000117525 ENSG00000149968 ENSG00000125538 ENSG00000113520 ENSG00000171105 ENSG00000104365 ENSG00000081041 ENSG00000115008 ENSG00000100906 ENSG00000173039 ENSG00000140465 ENSG00000073756 ENSG00000168610 ENSG00000108691 ENSG00000111537 ENSG00000115415 ENSG00000177606 ENSG00000100985 ENSG00000005381 PMC2854298__F8 AATF mediates anti-apoptotic effect of the unfolded protein response through transcriptional regulation of AKT1 ENSG00000275700 ENSG00000144895 ENSG00000168610 PMC6108862__F4 Functional analysis of transcription factors and genes in dysregulated miR-FFLs ENSG00000142192 ENSG00000150281 ENSG00000285109 ENSG00000136997 ENSG00000168610 PMC7554191__F9 Mechanism of EMAP II/ S1P signaling and modulation of S1P homeostasis ENSG00000170989 ENSG00000180739 ENSG00000213694 ENSG00000125910 ENSG00000267534 PMC4002915__F2 Signal pathways of IL-17 ENSG00000131323 ENSG00000175104 ENSG00000112115 ENSG00000177663 ENSG00000163702 PMC6909960__F1 Multiple factors regulate COX-2 expression ENSG00000132196 ENSG00000105401 ENSG00000172936 ENSG00000127191 ENSG00000073756 ENSG00000146648 ENSG00000184216 ENSG00000106546 PMC5910288__F3 Interactions between cellular metabolism, the circadian molecular clock, and ion channels ENSG00000105835 ENSG00000148798 ENSG00000142082 ENSG00000105227 PMC4136892__F7 Signaling pathway regulation in human schwannomas ENSG00000167601 ENSG00000186575 PMC3539739__F1 Oncogenic Transcription Factors: Cornerstones of Inflammation-Linked Pancreatic Carcinogenesis ENSG00000019991 ENSG00000112576 ENSG00000135446 ENSG00000138798 ENSG00000105810 ENSG00000164690 ENSG00000162692 ENSG00000128602 ENSG00000168610 ENSG00000146648 ENSG00000121966 ENSG00000062716 PMC4574709__F2 Meta-Analysis of Microarray Data of Rainbow Trout Fry Gonad Differentiation Modulated by Ethynylestradiol ENSG00000145604 ENSG00000132646 ENSG00000123374 ENSG00000164754 ENSG00000205250 ENSG00000277273 ENSG00000166851 ENSG00000093009 PMC8276021__F4 T Cell Protein Tyrosine Phosphatase in Glucose Metabolism ENSG00000112964 ENSG00000115415 ENSG00000115138 PMC2940738__F7 ETS-4 Is a Transcriptional Regulator of Life Span in Caenorhabditis elegans PMC5145803__F1 Redox states of the mitochondrial NAD and NADP pools are determined by a range of interconnected pathways ENSG00000124479 ENSG00000038002 ENSG00000112992 ENSG00000008130 ENSG00000105227 PMC8492275__F1 Therapeutic Effects of Polyphenols on the Treatment of Colorectal Cancer by Regulating Wnt Beta-Catenin Signaling Pathway ENSG00000134982 ENSG00000168036 PMC5726210__F3 The vitamin K cycle ENSG00000111341 PMC5161652__F7 Signaling events leading to MYC and YAP upregulation ENSG00000198793 ENSG00000136997 PMC6289210__F1 MALAT1 in cancer pathways.Notes: MALAT1 promotes generation of the six phenotypes of cancer ENSG00000162711 ENSG00000066044 ENSG00000170558 ENSG00000168036 PMC6102368__F5 VEGF and Notch interaction in physiological and tumor angiogenesis ENSG00000148400 ENSG00000074181 ENSG00000162692 ENSG00000077782 PMC6169142__F3 The protein C pathway ENSG00000180210 ENSG00000173599 ENSG00000166278 ENSG00000062485 ENSG00000236625 PMC8347175__F2 Stereoselective Synthesis of Novel Sphingoid Bases Utilized for Exploring the Secrets of Sphinx ENSG00000143753 ENSG00000221968 ENSG00000168350 PMC6370526__F1 Endoplasmic reticulum stress and monogenic kidney diseases in precision nephrology ENSG00000128272 ENSG00000127191 PMC10237023__F2 Intratumour microbiome of pancreatic cancer ENSG00000162711 ENSG00000081041 ENSG00000187796 ENSG00000137033 ENSG00000163739 ENSG00000110651 ENSG00000136869 PMC11806117__F7 Amino acid metabolism during liver repair and regeneration ENSG00000150907 ENSG00000169710 ENSG00000146648 ENSG00000115419 PMC11806117__F6 Lipid metabolism during liver repair and regeneration ENSG00000019991 ENSG00000138798 ENSG00000198160 ENSG00000167910 ENSG00000113161 ENSG00000169710 ENSG00000168036 ENSG00000160867 ENSG00000183579 ENSG00000108375 ENSG00000172936 ENSG00000146648 ENSG00000173334 PMC11806117__F4 Canonical signaling pathways involved in liver repair and regeneration ENSG00000134982 ENSG00000086991 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000087586 ENSG00000096717 ENSG00000128602 ENSG00000168610 ENSG00000171604 PMC5998149__F5 Pathway analysis of selected metabolites PMC5390009__F1 Downstream signaling pathway of cytokines sharing the common G chain receptor: IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21 ENSG00000115415 ENSG00000105639 ENSG00000168610 PMC5056018__F1 Estrogen Signaling Pathway ENSG00000163235 ENSG00000291971 ENSG00000136997 PMC9709426__F2 Targeting ferroptosis, the achilles’ heel of breast cancer: A review ENSG00000162733 ENSG00000151012 ENSG00000160867 ENSG00000108924 ENSG00000167468 ENSG00000168610 ENSG00000196628 ENSG00000123983 PMC9709426__F1 Targeting ferroptosis, the achilles’ heel of breast cancer: A review ENSG00000168003 ENSG00000151012 ENSG00000167468 ENSG00000113161 ENSG00000111684 ENSG00000127948 PMC2064799__F9 New calpain-dependent switch that controls cell spreading and retraction ENSG00000070831 ENSG00000291971 ENSG00000163914 PMC7697663__F3 Early antigen-driven transcriptional pathway in effector CDT8 T cells and in exhausted CD8 T cells ENSG00000156127 ENSG00000137265 ENSG00000020633 ENSG00000198846 PMC11594238__F4 Hormone synthesis and signal transduction pathways ENSG00000105722 ENSG00000108582 ENSG00000221818 PMC7697663__F1 c-Jun/activator protein-1 (AP-1) regulation and biological activity ENSG00000156127 ENSG00000137265 PMC6507908__F9 Elevated androgens alter intrafollicular regulatory mechanisms that impact the expression of VCAM1 and the expansion of VCAM1+ cells in the stroma ENSG00000162692 PMC5327483__F4 New targets to alleviate skeletal muscle inflammation: role of microRNAs regulated by adiponectin ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000064012 ENSG00000184216 PMC10367551__F8 Mechanism by which miR-552-3p alleviates liver fibrosis and inflammation ENSG00000108691 ENSG00000291748 ENSG00000120437 ENSG00000108821 PMC11577739__F9 Elabela alleviates cuproptosis and vascular calcification in vitaminD3- overloaded mice via regulation of the PPARG /FDX1 signaling ENSG00000137714 PMC3079441__F3 Pharmacological activities of cardiotonic steroids such as ouabain ENSG00000253506 ENSG00000291971 ENSG00000146648 PMC8677397__F5 Sishen Pill Maintained Colonic Mucosal Barrier Integrity to Treat Ulcerative Colitis via Rho/ROCK Signaling Pathway ENSG00000148400 ENSG00000125538 ENSG00000163914 ENSG00000015285 PMC4931096__F1 Biosynthetic pathways and the transformation of H2S in the mammalian body ENSG00000205221 PMC12228400__F11 Schematic diagram illustrating the antagonistic mechanism employed by ASFV MGF505-4R on IFN-I responses ENSG00000183735 ENSG00000164430 ENSG00000105397 PMC4933697__F2 Signaling pathways involved in platelet-mediated NET formation ENSG00000291971 ENSG00000136869 ENSG00000005381 PMC8850700__F1 LncRNA DUXAP10 Could Function as a Promising Oncogene in Human Cancer ENSG00000198793 ENSG00000168036 PMC5818890__F4 Common highly linked molecules and their most significantly related signaling pathways and functions in the “matrine-CRC” merged network ENSG00000111537 ENSG00000005339 ENSG00000291971 ENSG00000186716 ENSG00000163914 ENSG00000136997 ENSG00000189403 ENSG00000136869 ENSG00000095002 ENSG00000122512 ENSG00000132341 ENSG00000167701 PMC8850700__F2 LncRNA DUXAP10 Could Function as a Promising Oncogene in Human Cancer ENSG00000198793 ENSG00000183840 ENSG00000168036 PMC8773517__F3 Oxysterols in the Immune Response to Bacterial and Viral Infections ENSG00000128272 ENSG00000138135 ENSG00000144895 ENSG00000110048 PMC8773517__F2 Oxysterols in the Immune Response to Bacterial and Viral Infections ENSG00000138135 ENSG00000276561 ENSG00000135929 ENSG00000169508 PMC9208265__F3 Autophagy, ferroptosis, pyroptosis, and necroptosis in tumor immunotherapy ENSG00000108691 ENSG00000167468 ENSG00000198793 ENSG00000189403 ENSG00000136869 ENSG00000167419 PMC9208265__F2 Autophagy, ferroptosis, pyroptosis, and necroptosis in tumor immunotherapy ENSG00000168003 ENSG00000278718 ENSG00000162711 ENSG00000135218 ENSG00000151012 ENSG00000115415 ENSG00000167468 ENSG00000145649 ENSG00000073605 ENSG00000167419 PMC7382747__F3 Relevant signaling pathway in itaconate-induced anti-inflammatory and antioxidative effects ENSG00000117525 ENSG00000162772 ENSG00000084774 ENSG00000079999 PMC4435780__F1 Adipocyte receptors that have been proposed to promote the browning of white fat or maintenance of a brown adipocyte (BA) phenotype ENSG00000166819 ENSG00000142611 ENSG00000096717 PMC3181077__F1 NFKB activation pathways and the impact of S-glutathionylation ENSG00000104856 ENSG00000125538 ENSG00000173039 PMC9304715__F5 Hepatocyte-Conditional Knockout of Phosphatidylethanolamine Binding Protein 4 Aggravated LPS/D-GalN-Induced Acute Liver Injury via the TLR4/NFKB Pathway ENSG00000134020 ENSG00000136869 ENSG00000005381 PMC7204633__F2 Hypoxia driven interaction network that links CHI3L1 and TNFRSF12A to thyroid cancer ENSG00000133048 ENSG00000171791 ENSG00000100985 ENSG00000006327 ENSG00000112715 ENSG00000163631 PMC4614824__F1 Cystathionine Gamma-lyase (CSE), the biosynthetic enzyme for cysteine is depleted in Huntington's disease (HD) at the transcriptional level ENSG00000130699 ENSG00000185591 ENSG00000188158 PMC3413998__F6 Canonical Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000078579 ENSG00000136997 ENSG00000168036 PMC9100302__F1 An overview of current drugs and prophylactic vaccines for coronavirus disease 2019 (COVID-19) ENSG00000130234 PMC7013599__F4 Gene expressions in the fatty acid biosynthesis pathway (Ko00061) in response to Bgt infection ENSG00000182511 ENSG00000169710 ENSG00000280548 ENSG00000026103 PMC8524389__F4 Proteomic signatures for perioperative oxygen delivery in skin after major elective surgery: mechanistic sub-study of a randomised controlled trial ENSG00000142192 PMC9395173__F1 Using human data on cardiovascular risk associated with T1DM to guide mechanistic studies in mouse models ENSG00000143546 ENSG00000163220 PMC8529875__F5 Mini Review: Biomaterials in Repair and Regeneration of Nerve in a Volumetric Muscle Loss ENSG00000100811 ENSG00000166278 ENSG00000106459 PMC8836112__F1 Metformin and Insulin Resistance: A Review of the Underlying Mechanisms behind Changes in GLUT4-Mediated Glucose Transport ENSG00000171105 ENSG00000110395 PMC6362621__F1 VEGFA-VEGFR2 signaling pathways and their pharmacological inhibition occur across the glomerular filtration barrier ENSG00000157764 ENSG00000198793 ENSG00000112715 PMC1828071__F1A Intracellular Signaling in Insulin-mediated Regulation of Drug Metabolizing Enzyme Gene and Protein Expression ENSG00000002330 ENSG00000005882 ENSG00000150907 ENSG00000106070 ENSG00000198793 ENSG00000164327 ENSG00000105723 PMC4855676__F2 NFAT signaling pathway ENSG00000168264 ENSG00000177606 PMC8001776__F2 Routes for the in vivo production of glyceraldehyde (GA)/methylglyoxal (MGO) PMC3877547__F9 Schematic model of cancer-derived IgG to enhance cell growth and proliferation through inducing the production of a low level of ROS ENSG00000132341 PMC6400807__F7 The sketch of the mechanism of lncRNA SNHG16 on JAK2/STAT3 signaling pathway ENSG00000168610 PMC5932832__F3 Proteins of acute-phase signalling at stage II compared with stage I in non-responders to autologous chondrocyte implantation (ACI) ENSG00000180210 ENSG00000113905 ENSG00000099985 ENSG00000145192 ENSG00000105697 ENSG00000122194 ENSG00000171560 ENSG00000132693 ENSG00000165471 ENSG00000106927 PMC9400419__F1 Targeting the Hippo pathway in heart repair ENSG00000150457 ENSG00000131023 PMC3732055__F1 PAM and Copper – a Gene/Nutrient Interaction Critical to Nervous System Function ENSG00000123191 ENSG00000177556 PMC4855676__F5 Regulation of the apoptosis signaling pathway by NFAT proteins ENSG00000084774 PMC3256998__F5 Alpha-Tocopherol Alters Transcription Activities that Modulates Tumor Necrosis Factor Alpha (TNFA) Induced Inflammatory Response in Bovine Cells ENSG00000019582 PMC3928478__F2 Inositol phosphates and Akt/PKB inhibition, a potential Akt/PKB feedback mechanism.Note: Adapted from Cell, 143(6), Manning BD, Insulin signaling: inositol phosphates get into the Akt, 861–863 ENSG00000169047 ENSG00000176095 PMC5707523__F1 Viral modulation of death-receptor mediated apoptosis ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC4464690__F3 Crosstalk between Wnt, PTH and BMP signalling in cartilage and bone cell lineages ENSG00000178860 ENSG00000152266 ENSG00000281324 ENSG00000162337 PMC3256998__F6 Alpha-Tocopherol Alters Transcription Activities that Modulates Tumor Necrosis Factor Alpha (TNFA) Induced Inflammatory Response in Bovine Cells ENSG00000149269 PMC9103886__F1 Omega-3 Polyunsaturated Fatty Acids Provoke Apoptosis in Hepatocellular Carcinoma through Knocking Down the STAT3 Activated Signaling Pathway: In Vivo and In Vitro Study ENSG00000019991 ENSG00000087245 ENSG00000291971 ENSG00000171791 ENSG00000100985 ENSG00000168610 PMC5915505__F2 HIF degradation pathway in normoxia and its stabilisation in hypoxia and pseudohypoxia ENSG00000134086 ENSG00000178922 PMC6770306__F2 DNA damage response network in SCLC cells ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000083093 ENSG00000164754 ENSG00000051180 ENSG00000310560 PMC4075038__F3 Signal Transduction in Vasculogenesis and Developmental Angiogenesis ENSG00000107338 ENSG00000070831 ENSG00000291971 ENSG00000140575 ENSG00000061273 PMC4233246__F7 A model of how a p66B/Sufu complex inhibits Gli transcriptional activity and a Mycbp/Gli complex enhances Gli transcriptional activity in the nucleus ENSG00000214114 PMC5861430__F8 Working model of the molecular mechanism of APE2-mediated ATR–Chk1 DDR pathway from a defined SSB structure ENSG00000175054 ENSG00000164053 ENSG00000132646 ENSG00000138385 PMC4511103__F4 Programmed Cell Death in Animal Development and Disease ENSG00000277641 PMC8484370__F3 Distinct TLR signaling in the salamander response to tissue damage ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 ENSG00000164342 PMC4940079__F6 Differentially expressed gene distribution in the rno03320 pathway ENSG00000150991 ENSG00000100979 ENSG00000165269 PMC6698931__F1 The Function and Therapeutic Potential of Epstein-Barr Virus-Encoded MicroRNAs in Cancer ENSG00000132906 ENSG00000002330 ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000064012 ENSG00000164305 ENSG00000026103 PMC4940079__F7 Differentially expressed gene distribution in rno03320 pathway ENSG00000150991 ENSG00000134982 ENSG00000100979 ENSG00000165269 PMC3159971__F2 Mathematical model of dual negative feedback regulation of JAK2-STAT5 signaling ENSG00000187266 PMC8717028__F1 Nuclear receptors modulate inflammasomes in the pathophysiology and treatment of major depressive disorder ENSG00000278718 ENSG00000125538 ENSG00000106546 ENSG00000132170 PMC8580948__F3 Inhibition of Wnt-Beta-Catenin Signaling by ICRT14 Drug Depends of Post-Transcriptional Regulation by HOTAIR in Human Cervical Cancer HeLa Cells ENSG00000177606 ENSG00000196628 ENSG00000102974 PMC3999257__F4 NRG1 signalling and neurite formation mediators ENSG00000027075 ENSG00000104435 ENSG00000109320 ENSG00000162924 PMC7005066__F1 Unfolded protein response (UPR) signaling during bacterial infection ENSG00000163464 ENSG00000128272 ENSG00000144895 ENSG00000168040 PMC12031541__F1 Interaction of autonomous parvoviruses with cellular DDR factors ENSG00000188486 ENSG00000149311 ENSG00000012048 ENSG00000175054 ENSG00000164053 ENSG00000051180 ENSG00000139618 PMC6237163__F7 The effect of fold change with RNA-seq analysis for toll-like receptor nine signaling pathway in lung ENSG00000239732 ENSG00000109320 ENSG00000172936 ENSG00000184216 PMC6237163__F6 Result of RNA-seq mainly involves the signaling pathway ENSG00000277336 ENSG00000033327 ENSG00000134215 ENSG00000169032 ENSG00000135341 ENSG00000168811 ENSG00000010671 ENSG00000150782 ENSG00000239732 ENSG00000213658 ENSG00000178573 ENSG00000282604 ENSG00000169429 ENSG00000113520 ENSG00000164400 ENSG00000124181 ENSG00000113525 ENSG00000104365 ENSG00000100906 ENSG00000147168 ENSG00000109320 ENSG00000269335 ENSG00000213341 ENSG00000043462 ENSG00000117020 ENSG00000111537 ENSG00000010810 ENSG00000107485 ENSG00000172936 ENSG00000175104 ENSG00000131196 ENSG00000184216 PMC12031541__F3 AAV life cycle and DNA Damage Response (DDR) signaling ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000164053 PMC4132269__F2 Vascular inflammation, NK cell/monocyte crosstalk and angiotensin II in cardiac ischemic injury ENSG00000108557 ENSG00000117091 ENSG00000162692 ENSG00000204520 ENSG00000121807 PMC3773046__F1 Reducing Sphingolipid Synthesis Orchestrates Global Changes to Extend Yeast Lifespan ENSG00000124479 ENSG00000101751 ENSG00000022267 PMC9023073__F7 Mechanism of Lipopolysaccharide Escaping the Intestinal Barrier in Megalobrama amblycephala Fed a High-Fat Diet ENSG00000135218 ENSG00000293532 PMC7821221__F1 Wnt5a exerts its intracellular effects by activating two non-canonical Wnt signaling pathways, or the interplay with the canonical Wnt signaling pathway ENSG00000154342 ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6515307__F1 Mechanisms contributing to regulation of tumor clearance by effector cells ENSG00000134982 ENSG00000163599 PMC9367504__F8 Inflammatory Mediators in Colorectal Cancer Hepatic Metastasis ENSG00000162711 ENSG00000081041 ENSG00000125538 PMC9367504__F7 Inflammatory Mediators in Colorectal Cancer Hepatic Metastasis ENSG00000163739 ENSG00000172936 PMC6252103__F2 aspartate Beta-hydroxylase (ASPH) may affect the progression of pancreatic cancer through the activation of Notch signaling pathway ENSG00000148400 ENSG00000100985 ENSG00000112715 ENSG00000073756 PMC7248261__F1 Pathophysiology of allergic contact dermatitis (ACD) ENSG00000111537 ENSG00000134982 ENSG00000125538 PMC6252103__F1 Transcriptional regulation of aspartate Beta-hydroxylase (ASPH) ENSG00000169047 ENSG00000168036 ENSG00000140443 ENSG00000198363 PMC4250230__F4 Targeting RAF kinases for cancer therapy: BRAF mutated melanoma and beyond ENSG00000019991 ENSG00000140443 PMC7242326__F9 Summary of the role of AHR ligands in blocking TGFB induced collagen deposition and myofibroblast formation in Thyroid eye disease ENSG00000106546 PMC9367504__F1 Inflammatory Mediators in Colorectal Cancer Hepatic Metastasis ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC9130478__F3 Regulatory Role of MicroRNAs on Phagocytes: A Potential Therapeutic Target for Chronic Diseases ENSG00000108691 ENSG00000136997 ENSG00000172936 ENSG00000157625 ENSG00000083799 ENSG00000132510 ENSG00000175104 ENSG00000146648 ENSG00000184216 ENSG00000113360 ENSG00000123908 PMC8102492__F7 4-1BB-p38 MAPK-Dkk1 signaling pathway in BMSCs of aged mice ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC6063970__F4 Mapping transcripts on KEGG pathway ENSG00000149311 ENSG00000175054 ENSG00000002330 ENSG00000198793 ENSG00000135114 ENSG00000127948 PMC5943174__F1 Plasticity of myeloid-derived suppressor cells in cancer ENSG00000140968 ENSG00000118520 ENSG00000168610 ENSG00000007171 PMC6436660__F3 Bioinformatics and miR-135a-3p gene profiling predicts p38 as a targeted signaling pathway ENSG00000214078 ENSG00000103343 ENSG00000173540 ENSG00000123154 ENSG00000288146 ENSG00000167840 ENSG00000160360 ENSG00000143486 ENSG00000187609 ENSG00000197037 ENSG00000124019 ENSG00000140280 ENSG00000140365 ENSG00000121413 ENSG00000102967 ENSG00000169957 ENSG00000186977 ENSG00000129347 ENSG00000167107 ENSG00000149485 ENSG00000135114 ENSG00000161513 ENSG00000130307 ENSG00000099326 ENSG00000101997 ENSG00000213995 PMC6998289__F2 Small peptides encoded by circRNAs and lncRNAs regulate tumor invasion, metastasis, and proliferation ENSG00000168036 ENSG00000172795 PMC6998289__F1 Small peptides encoded by circRNAs and lncRNAs regulate tumor proliferation ENSG00000101751 ENSG00000006712 ENSG00000143476 ENSG00000132646 ENSG00000048028 ENSG00000109670 PMC4791269__F5 Screening key microRNAs for castration-resistant prostate cancer based on miRNA/mRNA functional synergistic network ENSG00000104365 ENSG00000117020 ENSG00000135446 ENSG00000006451 ENSG00000132646 ENSG00000198793 ENSG00000136997 ENSG00000105810 ENSG00000145386 ENSG00000099804 ENSG00000062485 ENSG00000109670 PMC3216974__F7 S6K1 and 4E-BP1 Are Independent Regulated and Control Cellular Growth in Bladder Cancer ENSG00000087842 PMC3579607__F2 Mechanisms underlying modulation of HER2-directed therapy cardiotoxicity through aerobic exercise ENSG00000065361 ENSG00000285109 ENSG00000291971 ENSG00000198793 ENSG00000178568 PMC2820587__F3 AURKA interactions ENSG00000168036 ENSG00000087586 PMC3579607__F1 Mechanisms underlying HER2-directed therapy cardiotoxicity ENSG00000065361 ENSG00000285109 ENSG00000291971 ENSG00000198793 ENSG00000178568 PMC8264427__F3 Macrophages in Acute Myeloid Leukaemia: Significant Players in Therapy Resistance and Patient Outcomes ENSG00000108691 ENSG00000123496 ENSG00000133048 ENSG00000198793 ENSG00000169429 ENSG00000121807 PMC2704458__F2 Histone Acetylation in Drug Addiction ENSG00000125740 ENSG00000108840 PMC4447103__F1 Differentially expressed genes in adipocytokine signaling pathway of adipose tissue in pregnancy ENSG00000102871 ENSG00000198793 ENSG00000115138 ENSG00000132478 ENSG00000127191 ENSG00000168610 ENSG00000047932 PMC8124433__F10 Meta-Analysis of Methamphetamine Modulation on Amyloid Precursor Protein through HMGB1 in Alzheimer’s Disease ENSG00000150594 ENSG00000142192 ENSG00000149968 ENSG00000189403 ENSG00000115594 ENSG00000026103 PMC4036091__F2 Schematic diagram representing the hypothetical mechanisms of the insulin-dependent systemic (I) and insulin-independent direct (II) effects of metformin in the endometrium ENSG00000169047 ENSG00000198793 ENSG00000140443 PMC11532857__F5 MiRNAs in metastasis of HCC ENSG00000096063 ENSG00000168036 ENSG00000137845 ENSG00000168610 PMC11532857__F4 MicroRNAs in EMT process ENSG00000096063 ENSG00000198793 ENSG00000125347 ENSG00000168610 PMC12180341__F9 Potential mechanism by which PTS alleviates renal fibrosis ENSG00000150787 PMC5369137__F1 Metabolic pathway of clopidogrel and its targeted receptor ENSG00000165841 ENSG00000197408 ENSG00000140505 ENSG00000262243 PMC8863767__F11 Synergistic Effects of Toll-Like Receptor 1/2 and Toll-Like Receptor 3 Signaling Triggering Interleukin 27 Gene Expression in Chikungunya Virus-Infected Macrophages ENSG00000174125 ENSG00000108691 ENSG00000187608 ENSG00000108688 ENSG00000164136 ENSG00000136869 ENSG00000288185 ENSG00000105246 ENSG00000125347 ENSG00000276561 ENSG00000164342 PMC11532857__F7 MiRNAs regulating angiogenesis in HCC ENSG00000019991 ENSG00000087245 ENSG00000128917 ENSG00000134853 PMC11532857__F6 MiRNAs regulating glycolysis in HCC ENSG00000198793 ENSG00000159399 PMC11526712__F1 Study workflow: Four differential microbial strains were found in the fecal microbiota of Laiwu pigs and Lulai black pigs ENSG00000177575 ENSG00000115415 PMC11526712__F8 Pathways through which E PMC2667750__F8 Proposed pathway for polyoxin biosynthesis ENSG00000101751 ENSG00000188158 ENSG00000177084 ENSG00000166169 ENSG00000122008 ENSG00000122678 PMC3554122__F1 Summary of checkpoint factors ENSG00000276618 ENSG00000260314 PMC12115143__F1 Integrative scheme of multistep phosphorelay in plants ENSG00000169750 ENSG00000126458 PMC7156858__F2 Suppressive role of MIR143‐3p in rat sarcoma (RAS) signaling pathway ENSG00000198793 ENSG00000146648 ENSG00000196712 PMC4187614__F2 Rho GTPase signaling pathways regulating neuronal survival ENSG00000002330 ENSG00000163914 PMC8304872__F7 Apoptotic and Non-Apoptotic Modalities of Thymoquinone-Induced Lymphoma Cell Death: Highlight of the Role of Cytosolic Calcium and Necroptosis ENSG00000188486 ENSG00000132906 ENSG00000137275 ENSG00000167323 ENSG00000293604 ENSG00000189403 ENSG00000100219 ENSG00000168040 ENSG00000064012 ENSG00000164305 ENSG00000285379 ENSG00000084774 PMC6901991__F1 Schematic diagram of a cell with insulin/IGF signaling cascades depicted ENSG00000003056 ENSG00000002330 ENSG00000115457 ENSG00000198793 ENSG00000163453 ENSG00000140443 PMC8518101__F2 When to Measure Plasma Homocysteine and how to Place it in Context: The Homocystinurias ENSG00000110395 ENSG00000142273 PMC7731760__F4 Metabolic pathway of D-mannitol in O ENSG00000114268 PMC9277484__F4 Embryonic Programs in Cancer and Metastasis—Insights From the Mammary Gland ENSG00000138795 ENSG00000281324 ENSG00000106571 ENSG00000121068 ENSG00000197757 ENSG00000134569 ENSG00000120149 ENSG00000135903 ENSG00000135111 ENSG00000107485 ENSG00000163132 PMC10610064__F1 ABL Kinase Activation and Signaling in Solid Tumors ENSG00000038382 ENSG00000181019 ENSG00000291971 ENSG00000198793 ENSG00000163914 ENSG00000143322 ENSG00000173406 ENSG00000121966 PMC7731760__F5 Metabolic pathway of cordycepin in O ENSG00000156110 ENSG00000167325 ENSG00000171848 ENSG00000185129 ENSG00000146676 PMC9277484__F3 Embryonic Programs in Cancer and Metastasis—Insights From the Mammary Gland ENSG00000070193 ENSG00000106571 ENSG00000135960 ENSG00000169047 ENSG00000128602 ENSG00000178568 ENSG00000140443 PMC3945866__F6 In addition to the known pathways that activate hepcidin expression, we show that Ras/RAF-triggered signals and the mTOR pathway are involved in hepcidin suppression ENSG00000100811 ENSG00000005339 ENSG00000198793 PMC2270259__F3 Central metabolism ENSG00000122966 ENSG00000172005 PMC10889086__F1 Bruton’s Tyrosine Kinase Inhibitors: Recent Updates ENSG00000177455 ENSG00000095585 ENSG00000110448 ENSG00000186716 ENSG00000197943 ENSG00000172936 ENSG00000010671 ENSG00000198286 PMC7988095__F2 AhR signaling pathway ENSG00000106546 PMC8744248__F3 Recent advances in systemic therapy for hepatocellular carcinoma ENSG00000134982 PMC3272705__F1 Subcellular itineraries of paradigmatic substrates of ubiquitin-dependent sorting pathways ENSG00000110395 ENSG00000099985 ENSG00000036672 ENSG00000146648 PMC11906681__F3 Targeted therapy in pediatric central nervous system tumors: a review from the National Pediatric Cancer Foundation ENSG00000198793 ENSG00000145979 ENSG00000140443 PMC8539723__F3 Cytokine Networks in the Pathogenesis of Rheumatoid Arthritis ENSG00000168610 PMC6844630__F1 Mechanisms of action of miR-21 showing the regulation of the WNT signaling pathway in NAFLD mice ENSG00000281324 ENSG00000168036 PMC11906681__F2 Targeted therapy in pediatric central nervous system tumors: a review from the National Pediatric Cancer Foundation ENSG00000106571 ENSG00000164690 ENSG00000128602 PMC5718065__F8 Schematic diagram illustrating potential interactions and changes in Ten-m3 KOs ENSG00000043355 ENSG00000135333 ENSG00000154928 PMC7438890__F1 Effect of local RAS on normal and leukemic hematopoiesis, as well as plasticity and systemic circulation, are shown () ENSG00000064601 PMC7204005__F3 miRNA-28-3p promotes cell proliferation through the MAPK signaling pathway and participates in the regulation of diabetes ENSG00000162889 ENSG00000284774 ENSG00000099985 ENSG00000070831 ENSG00000102871 ENSG00000291971 ENSG00000177606 ENSG00000171791 ENSG00000175104 ENSG00000127191 PMC5838831__F4 Sinalization cascade for genesis of medulloblastoma ENSG00000168036 ENSG00000164690 ENSG00000198125 PMC7204005__F5 miRNA promotes signal transduction and glucose protein binding through the TGF-beta signaling pathway and participates in the regulation of diabetes ENSG00000137834 ENSG00000157933 PMC5833345__F7 FBXL10-promoted DLBCL cell proliferation ENSG00000198901 ENSG00000183337 ENSG00000115289 PMC7204005__F4 miRNA-28-3p promotes cell proliferation and migration through the IGF signaling pathway and participates in the regulation of diabetes ENSG00000002330 ENSG00000198793 ENSG00000140443 PMC6457250__F5 Metabolic control of macrophage function ENSG00000125538 ENSG00000125347 ENSG00000168610 PMC9086853__F12 Peroxisome-Derived Hydrogen Peroxide Modulates the Sulfenylation Profiles of Key Redox Signaling Proteins in Flp-In T-REx 293 Cells ENSG00000074800 ENSG00000146733 ENSG00000152556 PMC1124928__F4 Coagulation, fibrinolysis, and angiogenesis in cancer ENSG00000003436 ENSG00000163737 ENSG00000122194 PMC5739687__F3 PPI network of proteins (A) up- and (B) down-regulated in renal oncocytoma ENSG00000197747 ENSG00000044115 ENSG00000130414 ENSG00000110799 ENSG00000204822 ENSG00000010278 ENSG00000055955 ENSG00000291944 ENSG00000064666 ENSG00000158042 ENSG00000291507 ENSG00000164405 ENSG00000038427 ENSG00000138757 ENSG00000197444 ENSG00000173599 ENSG00000110717 ENSG00000146701 ENSG00000275544 ENSG00000062485 ENSG00000119705 ENSG00000164904 ENSG00000142534 ENSG00000055950 ENSG00000136167 ENSG00000135631 ENSG00000166689 ENSG00000178127 ENSG00000100575 ENSG00000108179 ENSG00000144283 ENSG00000117122 ENSG00000127184 ENSG00000175198 ENSG00000213619 ENSG00000096080 ENSG00000171914 ENSG00000026508 ENSG00000126432 ENSG00000188783 ENSG00000082397 ENSG00000128951 ENSG00000140740 ENSG00000131495 ENSG00000073578 ENSG00000139531 ENSG00000163528 ENSG00000112992 ENSG00000116039 ENSG00000171345 ENSG00000106927 ENSG00000180210 ENSG00000133313 ENSG00000131730 ENSG00000074800 ENSG00000100714 ENSG00000104980 ENSG00000100412 ENSG00000180992 ENSG00000170266 ENSG00000099800 ENSG00000158874 ENSG00000113790 ENSG00000091140 ENSG00000182718 ENSG00000125166 ENSG00000026297 ENSG00000121310 ENSG00000284807 ENSG00000197081 ENSG00000259207 ENSG00000147684 ENSG00000138495 ENSG00000156467 ENSG00000126267 ENSG00000105953 ENSG00000174547 ENSG00000211445 ENSG00000215021 ENSG00000168275 ENSG00000106153 ENSG00000100348 ENSG00000138777 ENSG00000106554 ENSG00000122971 ENSG00000136003 ENSG00000016391 PMC7988095__F1 Intestinal stem cell compartment and molecular cascades related to AhR signaling ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000114315 ENSG00000146648 PMC3394958__F6 Schematic showing observed protein level alterations in VSCC proteome in the context of HPV infection ENSG00000115415 ENSG00000157601 ENSG00000168040 ENSG00000111331 ENSG00000146648 ENSG00000253729 ENSG00000026103 PMC7938726__F1 Diagram of osteoimmunology and potential regulatory sites of TCPTP ENSG00000107562 PMC5413910__F4 TNF-induced canonical NFKB and apoptosis pathways ENSG00000102871 ENSG00000083799 ENSG00000168040 ENSG00000154124 ENSG00000127191 PMC6497758__F3 Proposed Schematic diagram of the interaction of Mda5 with LGP2 in the RLR signaling pathway ENSG00000183735 ENSG00000088888 ENSG00000276561 PMC6497758__F2 Proposed Schematic diagram of Mda5 signaling pathway in Teleost based on a Mammalian Model ENSG00000183735 ENSG00000088888 ENSG00000276561 PMC7672768__F2 Protein-protein interaction (PPI) network constructed using the STRING online database and Cytoscape software ENSG00000142192 ENSG00000107562 ENSG00000058085 ENSG00000072274 ENSG00000134363 ENSG00000120885 ENSG00000138356 ENSG00000105894 ENSG00000274619 ENSG00000041982 ENSG00000011422 ENSG00000072210 ENSG00000143196 ENSG00000170477 ENSG00000187955 PMC5601664__F7 SENP3 grants tight junction integrity and cytoskeleton architecture in mouse Sertoli cells ENSG00000161956 ENSG00000079387 ENSG00000163904 ENSG00000112701 ENSG00000070831 ENSG00000138468 ENSG00000188612 ENSG00000168610 PMC8229713__F7 Two-way rectification method for identifying differentially expressed genes by maximizing the co-function relationship ENSG00000162711 ENSG00000111537 ENSG00000125538 ENSG00000172936 ENSG00000106100 ENSG00000064012 ENSG00000164305 PMC8308893__F6 Dietary Spray-Dried Porcine Plasma Reduces Neuropathological Alzheimer’s Disease Hallmarks in SAMP8 Mice ENSG00000118520 PMC1993861__F7 Model summarizing the hypothesis on narciclasine-mediated apoptosis ENSG00000168040 ENSG00000026103 PMC11922768__F8 The molecular architecture of plaque-associated axonal spheroids ENSG00000064601 ENSG00000102606 ENSG00000198793 ENSG00000120885 ENSG00000061676 ENSG00000006715 ENSG00000215305 ENSG00000198925 ENSG00000111229 ENSG00000067842 ENSG00000074800 ENSG00000291507 ENSG00000138757 ENSG00000157087 ENSG00000005893 ENSG00000220205 ENSG00000139970 ENSG00000120251 ENSG00000089597 ENSG00000142192 ENSG00000100321 ENSG00000196455 ENSG00000197102 ENSG00000070961 ENSG00000155876 ENSG00000069329 ENSG00000149357 ENSG00000133318 ENSG00000167552 ENSG00000127022 ENSG00000198626 ENSG00000143933 ENSG00000049860 ENSG00000102003 ENSG00000105402 ENSG00000132639 ENSG00000067715 ENSG00000118160 ENSG00000124406 ENSG00000196961 ENSG00000132718 ENSG00000175166 ENSG00000139116 ENSG00000072110 ENSG00000173692 ENSG00000141367 PMC4135307__F1 Adaptive immune resistance of acute myeloid leukemia (AML) ENSG00000111537 PMC7865845__F2 Role of the discussed NLRs in type I interferon signaling ENSG00000167207 ENSG00000140968 ENSG00000109606 ENSG00000174885 ENSG00000091106 ENSG00000106100 ENSG00000276561 ENSG00000273992 ENSG00000183735 ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000160703 ENSG00000179873 ENSG00000158077 ENSG00000142405 ENSG00000136869 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC4036234__F2 Cargo recognition and packaging in selective macroautophagy ENSG00000136436 ENSG00000123240 ENSG00000284099 ENSG00000034693 ENSG00000116977 PMC9696247__F1 Mammalian Target of Rapamycin (mTOR) Signaling at the Crossroad of Muscle Fiber Fate in Sarcopenia ENSG00000105550 ENSG00000158828 PMC3539299__F1 The phosphatase and tensin homolog deleted on chromosome ten (PTEN)/Akt pathway and its relationship to the androgen receptor (AR) based on the results of three papers published recently by the laboratories of Charles Sawyers, Damu Tang and Hong Wu ENSG00000198793 PMC10215262__F2 Studies related to the role of the Wnt/Beta-catenin signaling pathway in Acute Myeloid Leukemia ENSG00000118058 ENSG00000156076 ENSG00000164736 ENSG00000174804 ENSG00000020633 ENSG00000169884 ENSG00000134245 ENSG00000125084 PMC3423951__F1 The interplay between pituitary hormones and main signaling pathways of the IGF system in thyroid, adrenal and ovary cancers ENSG00000169047 ENSG00000198793 ENSG00000165409 PMC3483025__F1 Metabolic pathway of tetrapyrrole biosynthesis in plants ENSG00000144410 ENSG00000066926 ENSG00000126088 ENSG00000188690 ENSG00000127948 PMC10215262__F1 Canonical Wnt pathway ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000070831 ENSG00000134982 ENSG00000177606 ENSG00000185483 ENSG00000168036 PMC9368769__F4 Review on the Molecular Mechanisms of Action of Natural Products in Preventing Bone Diseases ENSG00000112977 ENSG00000170909 ENSG00000147614 ENSG00000168036 ENSG00000175104 ENSG00000143387 PMC12128263__F2 Three metabolic pathways in cells ENSG00000198793 ENSG00000115419 PMC6693056__F16 Summary of key estrogen-dependent mechanisms in endometriosis ENSG00000086696 ENSG00000168066 ENSG00000141448 ENSG00000125538 PMC12128263__F4 Schematic diagram of cysteine metabolism ENSG00000168003 ENSG00000151012 ENSG00000167468 PMC3929246__F1 Contribution of toll-like receptor signaling pathways to breast tumorigenesis and treatment ENSG00000174125 ENSG00000239732 ENSG00000170458 ENSG00000187554 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000198670 ENSG00000150455 ENSG00000175104 ENSG00000184216 ENSG00000164342 PMC8380544__F1 Novel hypothesis for COVID-19 pathogenesis: Retinol depletion and retinoid signaling disorder ENSG00000239732 ENSG00000198793 ENSG00000164342 PMC6297399__F5 String pathway enrichment analysis revealed strong associations (P=0.007) of the identified prognostic genes (colored nodes) ENSG00000019991 ENSG00000157404 ENSG00000049130 ENSG00000138798 ENSG00000134853 ENSG00000139613 ENSG00000136518 ENSG00000146648 ENSG00000127616 ENSG00000179295 ENSG00000198625 PMC5904546__F6 Cardiomyocytes and fructolytic pathway are strongly affected in P7 hearts ENSG00000042832 ENSG00000159399 PMC2805044__F1 The Akt/mTOR pathway in tobacco-carcinogen induced lung tumorigenesis ENSG00000124102 ENSG00000002330 PMC5904546__F5 Comparative analysis of differentially expressed proteomic and differentially regulated metabolomic data ENSG00000151726 ENSG00000138029 ENSG00000197142 PMC9371865__F8 LTBP2 Knockdown Promotes Ferroptosis in Gastric Cancer Cells through p62-Keap1-Nrf2 Pathway ENSG00000167468 ENSG00000119681 ENSG00000079999 PMC7870784__F4 Depiction of MAPK signaling pathway dysregulation and miRNAs in the KEGG database ENSG00000261857 ENSG00000196712 ENSG00000140443 PMC7870784__F3 Depiction of the MAPK signaling pathway in the KEGG database ENSG00000087095 ENSG00000288411 PMC7870784__F5 Model illustrating the miRSNP → miRNA → risk gene → pathway effect PSD PMC2707344__F4 Metabolic implication of leaf mitochondria during water stress ENSG00000149311 ENSG00000039537 ENSG00000172005 PMC6762067__F1 Ten simple rules to create biological network figures for communication ENSG00000180210 ENSG00000136158 ENSG00000142192 ENSG00000138798 ENSG00000067606 ENSG00000198576 ENSG00000146648 PMC6305291__F5 Glucose catabolism pathways and transport systems of strain A4B-17 ENSG00000150787 PMC5842210__F1 Pathogenesis of diabetes and its complications, reflecting where CCN proteins may take part ENSG00000136999 ENSG00000064205 PMC3372250__F5 The Hsp90 folding cycle ENSG00000131238 ENSG00000105401 PMC4197103__F1 Necroptotic signaling in adaptive and innate immunity ENSG00000137275 ENSG00000102871 ENSG00000136869 ENSG00000083799 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 ENSG00000164342 PMC8967065__F5 Instructive cues establishing PCP during kidney development ENSG00000188064 ENSG00000276799 PMC4970921__F1 Microarray and bioinformatics analysis of tendon fibroblasts treated with PRP or PPP ENSG00000012061 ENSG00000091986 ENSG00000148346 ENSG00000188313 ENSG00000172216 ENSG00000149968 ENSG00000162745 ENSG00000130222 ENSG00000166670 ENSG00000100985 ENSG00000102854 ENSG00000135919 PMC8967065__F4 Relationship between PCP and cystogenesis ENSG00000173218 ENSG00000104290 PMC8037356__F7 The signaling pathway in tested melanoma cells ENSG00000177169 ENSG00000144895 ENSG00000198793 ENSG00000164327 PMC8406487__F4 6‐Shogaol induces apoptosis in acute lymphoblastic leukaemia cells by targeting p53 signalling pathway and generation of reactive oxygen species ENSG00000168040 ENSG00000127191 ENSG00000135116 ENSG00000084774 PMC8967065__F3 PCP signaling in kidney development ENSG00000166341 ENSG00000162552 ENSG00000169071 ENSG00000173218 ENSG00000174804 ENSG00000143951 ENSG00000185483 ENSG00000083857 ENSG00000075275 ENSG00000198087 ENSG00000112655 ENSG00000104290 ENSG00000177283 PMC10385932__F1 Reigniting hope in cancer treatment: the promise and pitfalls of IL-2 and IL-2R targeting strategies ENSG00000100385 ENSG00000134460 ENSG00000113263 ENSG00000162772 ENSG00000105639 PMC5412393__F4 Potential contribution of protein disulfide isomerase (PDI) and various environmental factors in regulation of the TF-fVIIa complex on the surface of epithelial ovarian cancer (EOC) cells ENSG00000003436 PMC9048014__F5 Candidates for Biomarkers in Bipolar Disorder: A Proteomic Approach through Systems Biology ENSG00000180210 ENSG00000126218 ENSG00000117525 ENSG00000003436 ENSG00000110799 ENSG00000173599 ENSG00000175899 ENSG00000080618 ENSG00000122194 ENSG00000117322 ENSG00000062485 PMC9182524__F3 Review of Twenty Years of Research on the Regulation of Signaling Pathways by Natural Products in Breast Cancer ENSG00000002330 PMC9182524__F6 Review of Twenty Years of Research on the Regulation of Signaling Pathways by Natural Products in Breast Cancer ENSG00000125398 ENSG00000148400 ENSG00000137845 PMC4904147__F1 Antigen processing through MHC I molecules ENSG00000232326 ENSG00000273686 PMC3367714__F1 ATM/ATR DNA-damage response pathway ENSG00000149311 ENSG00000175054 ENSG00000164053 PMC7341754__F6 Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets ENSG00000245848 ENSG00000134982 ENSG00000168036 PMC4868905__F2 Metabolic changes triggered by ischemic insult and possible evolutions of the injury with the crosstalk between chemokines ENSG00000108691 ENSG00000081041 ENSG00000163734 ENSG00000169429 PMC10197881__F9 Proposed mechanisms ENSG00000132530 ENSG00000115415 ENSG00000138642 ENSG00000121807 PMC4905223__F1 OGT links cancer cell metabolism and cell survival via regulation of HIF-1A ENSG00000147162 ENSG00000198408 PMC11575457__F1 [KRAS signaling pathway and targeted therapeutic agents ENSG00000033327 ENSG00000198793 ENSG00000115904 ENSG00000160219 ENSG00000146648 ENSG00000140443 PMC3776465__F2 Functions of the proteins encoded by the genes mutated in primary lymphedema cluster around a central molecular pathway: the VEGFR3 signaling ENSG00000176692 ENSG00000183287 ENSG00000117707 ENSG00000037280 ENSG00000179348 ENSG00000138160 ENSG00000203883 ENSG00000150630 PMC9182524__F7 Review of Twenty Years of Research on the Regulation of Signaling Pathways by Natural Products in Breast Cancer ENSG00000175054 ENSG00000123374 ENSG00000105810 ENSG00000171791 PMC9506679__F2 Emerging roles of TRIM21 in coordinating cancer metabolism, immunity and cancer treatment ENSG00000094631 ENSG00000132109 PMC3539252__F3 Upregulated HCV gene signature is enriched for interferon (IFN) pathway genes ENSG00000213928 ENSG00000134321 ENSG00000183486 ENSG00000278032 ENSG00000111331 PMC4443295__F4 Schematic overview of the 7TM receptors judged to be either stimulating (in green to the right) or inhibiting (red or orange to the left and top) ghrelin secretion directly on the ghrelin cell ENSG00000132329 ENSG00000159224 ENSG00000036828 ENSG00000010310 PMC5778124__F6 Inhibitory nucleotide-binding oligomerization domain (NOD)-like receptors put the brake on NFKB activation via canonical and non-canonical pathways ENSG00000104856 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC8638432__F12 Exosomal microRNA-107 reverses chemotherapeutic drug resistance of gastric cancer cells through HMGA2/mTOR/P-gp pathway ENSG00000198793 ENSG00000145321 PMC4299512__F1 Select upstream regulators and downstream effectors of mTOR signaling ENSG00000118515 PMC2892366__F10 A model for the function of GCN2, ATF4, ASNS and Asn in conferring tumour cell protection from microenvironment stress ENSG00000115902 ENSG00000128272 ENSG00000144895 ENSG00000070669 PMC5571822__F1 EGFR pathway and mechanism of action of osimertinib.Abbreviation: EGFR, epidermal growth factor receptor; TGF, transforming growth factor ENSG00000163235 ENSG00000138798 ENSG00000198793 ENSG00000168610 PMC6830765__F1 NFKB pathway and the inhibitory effect of various alkyl nitrate N-Aryl Piperamide on NFKB translocation and COX-2 function ENSG00000125538 ENSG00000172936 ENSG00000105402 PMC5630446__F2 Bladder cancer stem cells: clonal origin and therapeutic perspectives ENSG00000106571 ENSG00000164690 PMC8863469__F16 29 m6A-RNA Methylation (Epitranscriptomic) Regulators Are Regulated in 41 Diseases including Atherosclerosis and Tumors Potentially via ROS Regulation – 102 Transcriptomic Dataset Analyses ENSG00000134982 ENSG00000116984 PMC4747503__F5 Comprehensive Expression of Wnt Signaling Pathway Genes during Development and Maturation of the Mouse Cochlea ENSG00000137474 ENSG00000062485 PMC7068531__F2 JAK-STAT-3 signaling pathway ENSG00000168610 PMC3561841__F1 Why stress is BAD for cancer patients ENSG00000002330 ENSG00000136997 PMC6230580__F2 Snail and cell-cycle progression ENSG00000132646 ENSG00000168036 ENSG00000118971 PMC5630446__F4 Bladder cancer stem cells: clonal origin and therapeutic perspectives ENSG00000134982 ENSG00000168036 PMC12081031__F1 Schematic displaying the unfolded protein response signalling pathway ENSG00000128272 ENSG00000100219 PMC4639861__F9 Model for Grhl2 function in coordinating differentiation and morphogenesis of airway epithelium ENSG00000170545 ENSG00000141579 ENSG00000074181 ENSG00000129654 ENSG00000087903 ENSG00000234602 PMC11092382__F2 Antitumor effects of sophocarpine through multiple signaling pathways ENSG00000170558 ENSG00000198793 ENSG00000100985 ENSG00000114315 PMC12081031__F3 The promotion of EMT by XBP1 ENSG00000169554 ENSG00000100219 PMC5537069__F6 Schematic representation showing downregulation of miR‐205 by ErbB2 signaling via Ras/Raf/MEK/ERK pathway PMC8959892__F2 Pyroptosis-Related Inflammasome Pathway: A New Therapeutic Target for Diabetic Cardiomyopathy ENSG00000198576 ENSG00000172936 ENSG00000136869 ENSG00000265972 ENSG00000096717 PMC4350284__F5 Activated SFK interfere with dimerization and nuclear translocation of pSTAT5A in BCR-ABL expressing cells ENSG00000033327 ENSG00000186716 PMC8224095__F1 Pharmacological Protection against Ischemia-Reperfusion Injury by Regulating the Nrf2-Keap1-ARE Signaling Pathway ENSG00000010810 ENSG00000079999 PMC3511450__F5 Non Linear Programming (NLP) Formulation for Quantitative Modeling of Protein Signal Transduction Pathways ENSG00000180815 ENSG00000140992 ENSG00000065675 ENSG00000169047 ENSG00000108443 ENSG00000173327 ENSG00000163558 ENSG00000089022 ENSG00000115594 ENSG00000162889 ENSG00000115590 ENSG00000065559 ENSG00000213341 ENSG00000166278 ENSG00000173402 ENSG00000163235 ENSG00000187554 ENSG00000172936 ENSG00000175104 ENSG00000146648 ENSG00000178568 ENSG00000033327 ENSG00000145365 ENSG00000291971 ENSG00000130758 ENSG00000138798 ENSG00000198793 ENSG00000095015 ENSG00000197442 ENSG00000142733 ENSG00000169032 ENSG00000162302 ENSG00000099942 ENSG00000139625 ENSG00000135341 ENSG00000114738 ENSG00000169967 ENSG00000073803 ENSG00000165458 ENSG00000263528 ENSG00000082512 ENSG00000125538 ENSG00000166501 ENSG00000027075 ENSG00000039537 ENSG00000104365 ENSG00000115008 ENSG00000157764 ENSG00000152495 ENSG00000065361 ENSG00000269335 ENSG00000281877 ENSG00000130159 ENSG00000105639 ENSG00000127191 ENSG00000168610 ENSG00000281614 ENSG00000185386 ENSG00000067606 ENSG00000100784 ENSG00000028137 PMC10239578__F4 Differential molecular pathway expression according to chemotherapeutic response in ovarian clear cell carcinoma ENSG00000139219 ENSG00000002330 ENSG00000189056 ENSG00000198793 ENSG00000134853 ENSG00000102678 PMC6698587__F1 Regulating mechanisms of UCA1 in multiple human cancers ENSG00000169554 ENSG00000137673 ENSG00000124766 ENSG00000168036 ENSG00000189403 ENSG00000171791 ENSG00000077782 ENSG00000124209 ENSG00000123908 PMC3303469__F1 Hypoxia inducible factor (HIF) pathway ENSG00000134086 PMC10884928__F1 NAD metabolic therapy in metabolic dysfunction-associated steatotic liver disease: Possible roles of gut microbiota ENSG00000105835 ENSG00000172890 ENSG00000123572 ENSG00000278488 PMC3013804__F3 Case study of the discovered phosphorylation networks associated with insulin signaling pathway ENSG00000171105 ENSG00000291603 ENSG00000002330 ENSG00000070831 ENSG00000149269 ENSG00000138798 ENSG00000169047 ENSG00000177606 ENSG00000136997 ENSG00000115904 ENSG00000166484 ENSG00000160691 PMC3562241__F6 Ihh and Runx2/Runx3 Signaling Interact to Coordinate Early Chondrogenesis: A Mouse Model ENSG00000020633 ENSG00000128602 ENSG00000163501 PMC10884928__F3 Prevotella along with NR supplements improving the signaling pathway of BCAA metabolism in MASLDNAD precursor supplements can affect fatty acid oxidation and lipid synthesis as well as the TCA cycle and insulin sensitivity ENSG00000105835 ENSG00000103507 ENSG00000175567 ENSG00000096717 ENSG00000026103 PMC4646490__F8 Alpha1a-Adrenoceptor Genetic Variant Triggers Vascular Smooth Muscle Cell Hyperproliferation and Agonist Induced Hypertrophy via EGFR Transactivation Pathway ENSG00000291507 ENSG00000291971 ENSG00000138798 ENSG00000146648 PMC7896234__F1 Mechanisms underlying microglial response to peripheral inflammation.(A) Schematic representation of the signaling pathway underlying changes in microglial Ca2+signaling, induced by peripheral inflammation ENSG00000162711 ENSG00000125538 PMC10669501__F2 Interplay of NRF2 in Kupffer cells and HSCs during the progression of chronic liver disease ENSG00000079999 PMC5974094__F1 Potential immune mechanism involved in vaccination with G10E-CS ENSG00000134982 ENSG00000062485 PMC9434901__F9 Oleuropein inhibits invasion of squamous cell carcinoma of the head and neck through TGFB1 signaling pathway PMC9011134__F7 Delivery of Basic Fibroblast Growth Factor Through an In Situ Forming Smart Hydrogel Activates Autophagy in Schwann Cells and Improves Facial Nerves Generation via the PAK-1 Signaling Pathway ENSG00000149269 ENSG00000171791 ENSG00000057663 PMC11695430__F1 Protein signaling pathway involving both DAMPs and selected cytokines in ICD modulation ENSG00000110944 ENSG00000171855 ENSG00000169245 ENSG00000111537 ENSG00000170606 ENSG00000189403 ENSG00000169429 ENSG00000113302 ENSG00000112115 ENSG00000168811 PMC6019623__F2 Synovial cell metabolism and chronic inflammation in rheumatoid arthritis ENSG00000198793 ENSG00000136997 PMC6224991__F1 Axels and brakes in the immune reaction ENSG00000291603 ENSG00000163599 PMC7582690__F2 PI3K/Akt signaling pathway converges to facilitate the progression OS ENSG00000043355 ENSG00000167601 ENSG00000168329 ENSG00000291971 ENSG00000198793 ENSG00000136235 PMC3342049__F2 Autophagy within antigen donor cells and cross-priming ENSG00000134982 ENSG00000164342 PMC6466304__F2 Diagram of major H4K20-related proteins and their proposed role in DNA double stranded break (DSB) repair ENSG00000133247 ENSG00000163961 ENSG00000110066 ENSG00000144554 ENSG00000109685 ENSG00000112130 ENSG00000197724 PMC4891302__F6 Co-targeting Androgen Receptor Splice Variants and mTOR signaling pathway for the Treatment of Castration-Resistant Prostate Cancer ENSG00000198793 PMC7194552__F4 Phosphatase and tensin homolog (PTEN), a p21-activated kinase (PAK)1 blocker, interferes with coronavirus-induced PAK1-dependent signaling pathway leading to lung fibrosis ENSG00000108691 ENSG00000130234 ENSG00000149269 PMC11063341__F1 Mechanism of Hippo pathway and the hippo targets of ncRNAs ENSG00000144560 ENSG00000197905 ENSG00000007866 ENSG00000074219 PMC3693466__F1 Insulin Signaling: Inositol Phosphates Get Into the Akt ENSG00000124102 ENSG00000169047 ENSG00000176095 PMC6767532__F1 Cyclooxygenase (COX) pathway and prostaglandin E2 (PGE2) signaling PMC6695051__F4 Result of the exploration of HTR1A functions involved in biological process pathways using the STRING database (http://string-db.org/newstring) ENSG00000150907 ENSG00000198793 ENSG00000164327 PMC4202123__F1 Structural basis for cancer treatment decisions ENSG00000198793 ENSG00000146648 PMC10041595__F5 NRF1 Regulates the Epithelial Mesenchymal Transition of Breast Cancer by Modulating ROS Homeostasis ENSG00000170558 ENSG00000277401 PMC2806370__F3 Pathway deregulation in ovarian cancer ENSG00000128602 ENSG00000102977 PMC4202123__F3 Structural basis for cancer treatment decisions ENSG00000019991 ENSG00000065361 ENSG00000198793 ENSG00000146648 PMC6484897__F1 TLR signaling and downstream molecules ENSG00000174125 ENSG00000172936 PMC2806370__F2 Cell cycle pathway gene expression ENSG00000112576 ENSG00000094880 ENSG00000141552 ENSG00000105329 ENSG00000184182 ENSG00000197629 ENSG00000250254 ENSG00000135476 ENSG00000164162 ENSG00000145386 ENSG00000118971 ENSG00000166851 ENSG00000134480 ENSG00000183765 ENSG00000153107 ENSG00000175054 ENSG00000113558 ENSG00000204634 ENSG00000123374 ENSG00000105810 ENSG00000139687 ENSG00000253729 ENSG00000170027 ENSG00000116717 ENSG00000117399 ENSG00000149311 ENSG00000145604 ENSG00000094804 ENSG00000134057 ENSG00000156970 ENSG00000135446 ENSG00000132646 ENSG00000115266 ENSG00000004897 ENSG00000149554 ENSG00000147082 ENSG00000080839 ENSG00000175305 PMC4264984__F5 Putative mechanism for EGCG-conducted cardioprotection against H2O2-induced oxidative stress through the Akt/GSK-3B /caveolae pathways in cultured H9c2 cells ENSG00000109452 ENSG00000074800 ENSG00000165119 ENSG00000073578 PMC3193288__F1 Innate immunity against RNA viruses in mammals ENSG00000183735 ENSG00000088888 ENSG00000164342 PMC6773405__F4 Focal adhesion pathway with enriched genes DOCK1, FLNB, FLT1, FYN, IGF1R, PPP1R12A ENSG00000136457 ENSG00000189056 ENSG00000038002 PMC6011061__F1 The Keap1/Nrf2 pathway and its epigenetic modification by SFN ENSG00000181019 ENSG00000175793 ENSG00000178573 ENSG00000079999 PMC7560597__F5 Complexity of interactions between autophagy machinery and the cGAS–STING pathway ENSG00000177169 ENSG00000183735 ENSG00000164430 ENSG00000157954 PMC7560597__F4 Interplay between the cGAS–STING signaling pathway and pyroptosis ENSG00000164430 ENSG00000163568 ENSG00000125538 PMC7560597__F3 Initiation of necroptosis by cGAS–STING signaling ENSG00000137275 ENSG00000168404 ENSG00000285379 ENSG00000142166 PMC7560597__F2 Interplay between the cGAS–STING signaling pathway and apoptosis ENSG00000183735 ENSG00000164430 ENSG00000120868 PMC7560597__F1 Activation of the cGAS–STING signaling pathway to drive innate immune responses ENSG00000183735 ENSG00000164430 PMC11091639__F8 PD-L1 regulatory signaling pathway [23] ENSG00000115415 ENSG00000172936 ENSG00000175104 PMC8414998__F2 Neuroinflammation in Autoimmune Disease and Primary Brain Tumors: The Quest for Striking the Right Balance ENSG00000111537 ENSG00000115415 ENSG00000163235 ENSG00000137265 ENSG00000184371 ENSG00000113520 ENSG00000168610 ENSG00000106546 PMC5323854__F7 Putative mechanism of necroptosis in the development of intestinal injury following intestinal I/R ENSG00000189403 ENSG00000136869 ENSG00000168404 PMC3457779__F1 The MAPK cascade activation and potential cross talk signals ENSG00000002330 ENSG00000010810 ENSG00000177606 ENSG00000171791 ENSG00000168040 PMC4926156__F2 VacA interferes with T-cell activation and proliferation by manipulating the T-cell receptor pathway and the cell cycle ENSG00000213658 ENSG00000177606 PMC7756807__F2 Energy‐generating regulators in Tregs ENSG00000136997 ENSG00000049768 PMC9598867__F1 Redox-Regulation in Cancer Stem Cells ENSG00000183734 ENSG00000026508 ENSG00000168036 ENSG00000164690 ENSG00000112715 ENSG00000128602 ENSG00000168646 PMC9537744__F1 Association between gene polymorphisms in the cyclophosphamide metabolism pathway with complications after haploidentical hematopoietic stem cell transplantation ENSG00000165841 PMC12096525__F11 a) LDH-mediated NT3 delivery enhances spinal cord repair: axonal regeneration and functional recovery in a murine model ENSG00000178860 ENSG00000182968 ENSG00000170558 ENSG00000103335 PMC2806300__F8 Reversal of EMT induced by TGFB1 ENSG00000169554 PMC9598867__F2 Redox-Regulation in Cancer Stem Cells ENSG00000181019 ENSG00000103222 ENSG00000164690 ENSG00000168765 ENSG00000079999 PMC7291237__F1 Late phase of the HIV-1 replication cycle ENSG00000173599 ENSG00000185591 ENSG00000167182 PMC10970097__F1 The PI3K/Akt/mTOR signaling pathway ENSG00000002330 PMC3695748__F6 Schema of regulatory mechanisms of endothelial atherosusceptibility discussed in the text ENSG00000127528 ENSG00000162692 ENSG00000136826 PMC4980327__F1 Molecular alterations cause metabolic switching in cancer cells and severe metabolic changes in the tumor microenvironment ENSG00000198793 ENSG00000136997 ENSG00000078237 ENSG00000284194 ENSG00000115419 PMC5992820__F1 Simplified schematic diagram of the pathways described in this study ENSG00000065361 ENSG00000169047 ENSG00000140443 PMC4725600__F1 Mdm network and its regulation of p53 activities: a rheostat of cancer risk ENSG00000136997 ENSG00000198625 PMC3473263__F4 Sample regulation summary diagrams for E ENSG00000145723 ENSG00000132693 PMC6141435__F1 Hippo signaling pathway in Mammals ENSG00000129474 ENSG00000186575 ENSG00000169435 PMC3278889__F6 CD40 signaling to the alternative NFKB pathway ENSG00000104856 ENSG00000131323 PMC3278889__F5 T-cell receptor (TCR) signaling to NFKB ENSG00000173599 ENSG00000198286 PMC3278889__F4 TLR4 signaling to NFKB ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC9208314__F1 Translation initiation pathway ENSG00000163435 ENSG00000120690 ENSG00000100664 PMC8038076__F8 GR-SC65 suppresses the PM-induced ROS-dependent apoptosis pathway ENSG00000142192 ENSG00000175104 ENSG00000127191 PMC12222324__F3 FOXM1 involved in chemoresistance in ovarian cancer ENSG00000198793 ENSG00000185591 PMC7933973__F1 Current mechanisms underlying KLF5 effects on kidney diseases ENSG00000143546 ENSG00000163220 ENSG00000135446 ENSG00000198670 ENSG00000109670 PMC12222324__F2 FOXM1 in ovarian cancer development ENSG00000145604 ENSG00000186081 ENSG00000134057 ENSG00000112984 ENSG00000168036 ENSG00000101224 ENSG00000166851 ENSG00000135480 ENSG00000159399 PMC2518073__F8 Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer ENSG00000169047 PMC10276824__GA FOXO1 regulates Th17 cell-mediated hepatocellular carcinoma recurrence after hepatic ischemia-reperfusion injury ENSG00000150907 PMC8881489__F1 Radiotherapy: Brightness and darkness in the era of immunotherapy ENSG00000169248 ENSG00000169245 ENSG00000164430 ENSG00000138755 ENSG00000189403 PMC3683810__F8 Proposed model of p38 MAPK regulation of mRNA translation ENSG00000288145 ENSG00000125538 ENSG00000284161 ENSG00000167658 ENSG00000139549 PMC8555654__F6 Semaphorin3F Drives Dendritic Spine Pruning through Rho-GTPase Signaling ENSG00000106683 ENSG00000156299 ENSG00000149269 ENSG00000067900 ENSG00000182541 PMC8783172__F4 What’s happening where when SARS-CoV-2 infects: are TLR7 and MAFB sufficient to explain patient vulnerability? ENSG00000172936 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC4017430__F1 Leptin receptor signaling ENSG00000168610 PMC8365877__F3 Immunological Involvement of MicroRNAs in the Key Events of Systemic Lupus Erythematosus ENSG00000177455 ENSG00000186716 ENSG00000134061 PMC7243768__F2 SARS-CoV-2 enters into the host cell via binding with the cellular receptor ACE-2 ENSG00000169245 ENSG00000134982 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC6629926__F1 The role of ARG1 and IDO1 in neoplasia and autoimmunity ENSG00000291971 ENSG00000118520 ENSG00000106546 PMC9030544__F4 Proteomic Analysis of Endometrial Cancer Tissues from Patients with Type 2 Diabetes Mellitus ENSG00000173898 ENSG00000072110 PMC8900363__F7 Increased phosphatase regenerating liver-1 trigger vascular remodeling in injured ovary via platelet-derived growth factor signaling pathway ENSG00000104899 ENSG00000130385 ENSG00000291971 ENSG00000106410 ENSG00000198793 ENSG00000174804 ENSG00000146648 PMC2782081__F1 An overview of miRNA biogenesis ENSG00000100697 ENSG00000128191 ENSG00000113360 ENSG00000132341 PMC3278592__F3 The pleiotropic effects of erythropoietin in infection and inflammation ENSG00000186716 ENSG00000187266 PMC9138110__F11 Transcriptome Analysis of Breast Muscle Reveals Pathways Related to Protein Deposition in High Feed Efficiency of Native Turkeys ENSG00000135218 ENSG00000092621 ENSG00000146733 PMC7139589__F3 Extracellular domain consists of five cadherin-type repeats bound together by calcium ions, forming a parallel cadherin dimer ENSG00000138798 ENSG00000168036 ENSG00000146648 PMC5278183__F1 Regulation of Ciliogenesis by Inputs from the Cell Cycle ENSG00000094631 ENSG00000117650 ENSG00000182504 ENSG00000186638 ENSG00000087586 ENSG00000007047 ENSG00000166851 PMC5278183__F3 Relationships Between Cellular Proteostasis and Ciliogenesis ENSG00000094631 ENSG00000140463 ENSG00000109083 ENSG00000126775 ENSG00000156313 ENSG00000087586 ENSG00000057663 PMC6290922__F5 T-bet: a bridge between innate and adaptive immunity ENSG00000186810 ENSG00000138378 ENSG00000111537 ENSG00000139187 ENSG00000183625 ENSG00000150907 ENSG00000198793 ENSG00000020633 ENSG00000126353 PMC5119679__F1 Hydrogen sulfide (H2S) regulating mesenchymal stem cell (MSC) function ENSG00000178860 ENSG00000165125 ENSG00000168036 PMC5278183__F2 Regulatory Roles of the Cytoskeleton at the Base of the Cilia ENSG00000094631 ENSG00000140463 ENSG00000099204 ENSG00000291971 ENSG00000087586 ENSG00000166851 ENSG00000173210 ENSG00000182541 PMC3584867__F9 The multiple functions of PE ENSG00000039537 ENSG00000113600 ENSG00000122194 PMC7577940__F1 Mechanosensation ENSG00000291971 ENSG00000131023 PMC4707207__F1 PI3K/Akt pathway ENSG00000153094 ENSG00000005882 ENSG00000169047 ENSG00000198793 PMC3636885__F8 STAT3-mediated coincidence detection regulates a noncanonical pathway of IEG induction ENSG00000005882 ENSG00000138798 ENSG00000168610 ENSG00000146648 ENSG00000105723 PMC3401455__F2 Rad51 filament formation and regulation ENSG00000132646 ENSG00000051180 PMC4985506__F7 The HGF/Met-FOXM1 positive feedback loop ENSG00000019991 ENSG00000134057 ENSG00000168610 PMC2927346__F1 Irinotecan pharmacogenomics ENSG00000172831 ENSG00000114200 ENSG00000109320 ENSG00000118777 ENSG00000042088 ENSG00000023839 ENSG00000262243 PMC3401455__F1 Models for the repair of DNA double-strand breaks ENSG00000051180 PMC5575202__F5 Significant association of the 97 gene signature with transcription factors TP53 and HIF1A ENSG00000100234 ENSG00000075223 ENSG00000186340 ENSG00000104783 ENSG00000101265 ENSG00000134762 ENSG00000122877 ENSG00000140285 ENSG00000134853 ENSG00000163453 ENSG00000171951 ENSG00000137801 PMC10055176__F8 Changes in Environmental Stress over COVID-19 Pandemic Likely Contributed to Failure to Replicate Adiposity Phenotype Associated with Krtcap3 ENSG00000153094 ENSG00000120149 ENSG00000113161 ENSG00000186480 ENSG00000052802 ENSG00000198911 PMC3820561__F1 BRCA1 domain structure and subcellular transport pathways ENSG00000012048 PMC8114929__F3 Rhizopine signalling to control PGPR ENSG00000090402 ENSG00000184207 ENSG00000102977 PMC3032036__F10 The paracellular pathway in vertebrates and insects ENSG00000134376 ENSG00000149564 ENSG00000101440 ENSG00000168036 ENSG00000132849 ENSG00000198910 PMC8874090__F4 Long non‐coding RNAs in diabetic wound healing: Current research and clinical relevance ENSG00000113070 ENSG00000083444 ENSG00000139372 ENSG00000117707 ENSG00000078098 ENSG00000166147 PMC12024770__F1 STEAP1 protein structure, biological function, and possible carcinogenic regulatory pathway ENSG00000253506 ENSG00000150907 ENSG00000168610 PMC8582580__F3 New Look of EBV LMP1 Signaling Landscape ENSG00000117228 ENSG00000102871 ENSG00000082512 ENSG00000137265 ENSG00000168036 ENSG00000285152 ENSG00000144791 ENSG00000105639 ENSG00000127191 ENSG00000276561 ENSG00000184216 PMC5907526__F8 Overview of the TLR4 signalling pathway ENSG00000125538 ENSG00000175104 PMC7503766__F7 Nodulation (NOD)-like receptor signaling pathway (PM vs ENSG00000142192 ENSG00000148798 PMC7662673__F8 Suggested mechanism by which nonanal induces the growth factors expression in DPCs via the cAMP signaling pathway ENSG00000138795 ENSG00000168036 PMC5176143__F3 Zrf1 controls the temporal expression of the genes related to cardiomyogenesis ENSG00000154342 ENSG00000166823 ENSG00000113196 ENSG00000285109 ENSG00000243709 ENSG00000147869 ENSG00000156574 ENSG00000164107 ENSG00000141052 ENSG00000089225 ENSG00000016082 PMC4997077__F1 Oxidative stress and mTORC1-mediated Treg cell differentiation ENSG00000049768 ENSG00000106546 PMC3136221__F1 “big picture” between DM2 and cancer ENSG00000198793 ENSG00000140443 PMC6854381__F6 CMTM7 activates Rab5 which controls the fusion of early endosomes and affects EGFR protein trafficking, an essential part of the PI3K/AKT signaling pathway ENSG00000138798 ENSG00000153551 ENSG00000146648 PMC5487703__F1 Trypsin-dependent pathological pathway in chronic pancreatitis ENSG00000274247 ENSG00000162438 ENSG00000164266 PMC9031703__F7 Pleiotropic Role of Long Non-Coding RNAs in the Modulation of Wnt/Beta-Catenin and PI3K/Akt/mTOR Signaling Pathways in Esophageal Squamous Cell Carcinoma: Implication in Chemotherapeutic Drug Response ENSG00000125651 ENSG00000134982 ENSG00000169047 ENSG00000198793 ENSG00000168036 PMC4516212__F5 Summary of the inhibitory effects of BSNXD on osteoclast differentiation.Notes: The suppression of BSNXD on RANKL-induced activation of the NFATc1 via ERA pathway is correlated with the inhibition of osteoclastogenesis ENSG00000175104 ENSG00000131196 PMC6281418__F7 Differential gene expression in human tissue resident regulatory T cells from lung, colon, and blood ENSG00000154342 ENSG00000154764 ENSG00000177606 ENSG00000136997 ENSG00000168646 ENSG00000146648 ENSG00000125084 PMC5415623__F7 Schematic pathway for low-dose PTX inhibition of cell growth in colorectal carcinoma cells ENSG00000151012 ENSG00000115419 PMC6146175__F5 STAT 3 signaling pathway and site of action of napabucasin ENSG00000087245 ENSG00000163914 PMC9031703__F6 Pleiotropic Role of Long Non-Coding RNAs in the Modulation of Wnt/Beta-Catenin and PI3K/Akt/mTOR Signaling Pathways in Esophageal Squamous Cell Carcinoma: Implication in Chemotherapeutic Drug Response ENSG00000065989 ENSG00000169047 ENSG00000198793 PMC9031703__F5 Pleiotropic Role of Long Non-Coding RNAs in the Modulation of Wnt/Beta-Catenin and PI3K/Akt/mTOR Signaling Pathways in Esophageal Squamous Cell Carcinoma: Implication in Chemotherapeutic Drug Response ENSG00000169047 ENSG00000198793 PMC6444804__F2 Hypothalamic Lipids and the Regulation of Energy Homeostasis ENSG00000242689 ENSG00000115138 ENSG00000175567 ENSG00000026103 PMC5326620__F1 Dual functions of IRF3 in antiviral defense ENSG00000183735 ENSG00000131323 ENSG00000175104 ENSG00000127191 PMC6997700__F1 Leaf lipid pathways and hypotheses for acyl flux into TAG ENSG00000173599 ENSG00000198670 ENSG00000026103 PMC6449224__F4 MicroRNAs regulate the smoking‐related ERBB2 signaling pathway ENSG00000002330 ENSG00000138798 ENSG00000113070 ENSG00000198793 ENSG00000158458 ENSG00000169752 ENSG00000169291 ENSG00000110395 ENSG00000148660 ENSG00000163235 ENSG00000124882 ENSG00000177606 ENSG00000136997 ENSG00000137843 PMC8958685__F6 Recent advance in treatment of atherosclerosis: Key targets and plaque-positioned delivery strategies ENSG00000135218 ENSG00000136869 ENSG00000169174 PMC7469327__F3 Action of the NLRP3 inflammasome ENSG00000278718 ENSG00000162711 ENSG00000144935 ENSG00000172936 ENSG00000110218 PMC2819006__F1 Key mechanisms involved in colorectal carcinogenesis ENSG00000134982 ENSG00000168036 ENSG00000095002 PMC5833072__F11 Schematic view of the potential mechanisms by which RNS60 protect motor neurons and ameliorate the neuromuscular impairment in ALS ENSG00000197971 ENSG00000131095 ENSG00000049768 PMC3331761__F4A Concordance of Changes in Metabolic Pathways Based on Plasma Metabolomics and Skeletal Muscle Transcriptomics in Type 1 Diabetes ENSG00000169047 ENSG00000124212 ENSG00000062485 PMC3282989__F2 Recapitulation of heart development can provide useful insight for optimizing differentiation protocols ENSG00000285109 ENSG00000156574 PMC7439102__F4 Signaling pathway diagram ENSG00000104499 ENSG00000149311 ENSG00000175054 ENSG00000132646 ENSG00000140464 PMC6879940__F1 Proposed mechanisms of podocyte susceptibility to lipid-mediated injury ENSG00000057252 ENSG00000162711 ENSG00000135218 ENSG00000042832 PMC2553712__F1 Design, Synthesis and Characterization of A Potent, Non-Peptide, Cell-Permeable, Bivalent Smac Mimetic that Concurrently Targets both the BIR2 and BIR3 Domains in XIAP ENSG00000120868 ENSG00000168040 PMC4271318__F8 FGF signaling specifies hematopoietic stem cells through its regulation of somitic Notch signaling ENSG00000160867 ENSG00000002745 ENSG00000091140 PMC4469999__F2 Complement cascades ENSG00000166278 PMC11634591__F1 CGAS-STING signaling pathway ENSG00000164430 ENSG00000276561 PMC4878431__F2 Schema of IR structure and insulin signaling pathways in vascular cells ENSG00000162692 PMC7400212__F1 In (A): Interactions of methionine cycle, folate cycle, transsulfuration and methylation pathway ENSG00000205221 ENSG00000136877 PMC10138709__F3 Canonical and non-canonical Wnt signalling ENSG00000134982 ENSG00000163914 PMC11634591__F4 cGAS-STING pathway in the liver plays a key role in mediating NAFLD/NASH/ALD ENSG00000183735 ENSG00000164430 ENSG00000136869 PMC11634591__F3 cGAS-STING pathway plays a critical role in mediating obesity in adipose tissue ENSG00000183735 ENSG00000164430 ENSG00000136869 PMC10138709__F5 Hippo pathway and its crosstalk with other signalling pathways ENSG00000087095 ENSG00000126016 ENSG00000186575 ENSG00000147162 ENSG00000109321 ENSG00000134982 ENSG00000144560 ENSG00000163914 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC11634591__F2 cGAS-STING pathway plays a significant role in mediating cardiovascular disease ENSG00000278718 ENSG00000183735 ENSG00000164430 ENSG00000150457 ENSG00000131023 PMC8103724__F1 Emerging roles for the autophagy machinery in extracellular vesicle biogenesis and secretion ENSG00000177169 ENSG00000083290 ENSG00000126775 ENSG00000198793 ENSG00000144848 ENSG00000167965 ENSG00000099940 ENSG00000145782 ENSG00000118640 ENSG00000136874 PMC7395311__F3 Cytokine and receptor Janus kinase pathway ENSG00000099985 ENSG00000242689 ENSG00000105397 ENSG00000145777 ENSG00000128342 ENSG00000105639 ENSG00000162892 ENSG00000105205 ENSG00000142224 PMC3898671__F2 Synthesis of the C5 isoprenoid precursors IPP and DMAPP ENSG00000067064 ENSG00000197429 ENSG00000167508 PMC11187367__F6 Summary of the findings ENSG00000177575 ENSG00000019582 ENSG00000150782 ENSG00000107562 ENSG00000026508 ENSG00000115718 ENSG00000266524 ENSG00000170891 PMC10138709__F2 Hedgehog signalling pathway ENSG00000136997 ENSG00000164690 ENSG00000128602 PMC3530456__F5 Identification of Epigenetically Altered Genes in Sporadic Amyotrophic Lateral Sclerosis ENSG00000167601 ENSG00000140564 ENSG00000204577 ENSG00000053438 ENSG00000169862 ENSG00000120149 ENSG00000197746 ENSG00000184185 ENSG00000020633 ENSG00000265972 ENSG00000186818 ENSG00000091137 ENSG00000242265 ENSG00000172216 ENSG00000188313 ENSG00000165879 ENSG00000187908 ENSG00000136235 ENSG00000077782 ENSG00000101333 ENSG00000174482 ENSG00000283934 ENSG00000124785 ENSG00000116396 ENSG00000111729 ENSG00000066382 ENSG00000164520 ENSG00000156427 ENSG00000107165 ENSG00000120594 ENSG00000152556 PMC3520539__F1 Generalized overview of the regulation of apoptosis by sphingolipids ENSG00000132906 ENSG00000002330 PMC7280066__F1 Regulatory functions of oncogenic and tumor suppressor long non-coding RNAs (lncRNAs) in the Wnt/Beta-catenin signaling pathway attributed to the pathogenesis of non-small cell lung cancer (NSCLC) ENSG00000125398 ENSG00000134982 ENSG00000124766 ENSG00000168036 PMC9503946__F10 Coronaviral Inhibitors of the Nucleocapsid Protein Identified In Silico and In Vitro from a Large Natural Product Library ENSG00000088888 ENSG00000137275 ENSG00000169429 ENSG00000121060 PMC4300866__F2 Three pathways of complement activation: classical, lectin, and alternative pathways ENSG00000039537 ENSG00000009724 ENSG00000291559 ENSG00000244731 ENSG00000166278 ENSG00000182326 ENSG00000236625 PMC8603497__F4 Transcriptome and metabolome analysis to reveal major genes of saikosaponin biosynthesis in Bupleurum chinense ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC3041769__F4 Antibodies against CD20 or B-Cell Receptor Induce Similar Transcription Patterns in Human Lymphoma Cell Lines ENSG00000072571 ENSG00000114993 ENSG00000070190 ENSG00000073060 ENSG00000134574 ENSG00000140379 ENSG00000171791 ENSG00000122862 ENSG00000095794 PMC4300866__F1 Biological functions of the complement system ENSG00000113600 ENSG00000186716 ENSG00000203710 ENSG00000117322 ENSG00000236625 PMC8957965__F8 Cajaninstilbene Acid Ameliorates Acetaminophen-Induced Liver Injury Through Enhancing Sestrin2/AMPK-Mediated Mitochondrial Quality Control ENSG00000130649 ENSG00000158828 PMC8842603__F1 Tankyrase Inhibitor for Cardiac Tissue Regeneration: an In-silico Approach ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000173273 PMC9319717__F2 Natural Biomolecules Targeting JAK/STAT/SOCS Signaling in the Management of Atopic Dermatitis ENSG00000171150 ENSG00000134982 ENSG00000204671 ENSG00000113520 PMC8671096__F2 Construction of synthetic microbial consortia for 2-keto-L-gulonic acid biosynthesis ENSG00000125166 ENSG00000139515 ENSG00000118520 ENSG00000146701 PMC5678971__F1 ULK/Atg1 redirects machinery used under vegetative conditions for stress-induced autophagy ENSG00000123395 ENSG00000083290 ENSG00000148396 PMC7525161__F7 Identified key pathways ENSG00000128342 ENSG00000084774 PMC8416724__F3 CD47/SIRPA pathway mediates cancer immune escape and immunotherapy ENSG00000164430 ENSG00000198053 PMC9534575__F2 Quaternary ammonium compounds in hypersensitivity reactions ENSG00000113520 ENSG00000145777 PMC2686461__F1 BCR signaling pathway ENSG00000186716 ENSG00000076641 PMC8416724__F2 CD47/SIRPA pathway mediates cancer immune escape and immunotherapy ENSG00000198053 ENSG00000136997 ENSG00000168036 ENSG00000011478 ENSG00000196628 PMC8103321__F1 APC Promoter Methylation in Gastrointestinal Cancer ENSG00000100811 ENSG00000165556 ENSG00000134982 ENSG00000198576 ENSG00000168036 ENSG00000115816 ENSG00000105698 PMC12025301__F1 Ferroptosis signaling pathway ENSG00000161905 ENSG00000167468 ENSG00000111684 ENSG00000115107 PMC3178610__F5 Determining Signalling Nodes for Apoptosis by a Genetic High-Throughput Screen ENSG00000163399 ENSG00000100906 ENSG00000181374 ENSG00000087460 ENSG00000281500 PMC4536022__F2 Integrative Analysis of MicroRNA and mRNA Data Reveals an Orchestrated Function of MicroRNAs in Skeletal Myocyte Differentiation in Response to TNFA or IGF1 ENSG00000167513 ENSG00000101057 ENSG00000145386 ENSG00000118971 ENSG00000166851 ENSG00000124762 ENSG00000094804 ENSG00000148773 ENSG00000102034 ENSG00000134057 ENSG00000105810 ENSG00000149554 ENSG00000130726 PMC6302218__F2 Autophagy and the inflammasome ENSG00000162711 ENSG00000125538 PMC5264637__F1 Targeted metabolomics shows plasticity in the evolution of signaling lipids and uncovers old and new endocannabinoids in the plant kingdom ENSG00000196839 PMC9637147__F1 Molecular mechanisms of ferroptosis ENSG00000135423 ENSG00000151012 ENSG00000197635 ENSG00000072274 ENSG00000113161 ENSG00000105953 ENSG00000211584 ENSG00000102967 ENSG00000076351 ENSG00000168003 ENSG00000119686 ENSG00000167468 ENSG00000111684 ENSG00000110911 ENSG00000127948 PMC9105255__F6 Systematic Review and Meta-Analysis of Mass Spectrometry Proteomics Applied to Human Peripheral Fluids to Assess Potential Biomarkers of Schizophrenia ENSG00000090402 ENSG00000154059 PMC6977534__F2 Roles of zinc transporters in B cells of different stages ENSG00000186716 PMC515251__F1 A minimal metabolism ENSG00000150787 PMC4399033__F1 Pyrimidine synthesis and salvage pathways in Toxoplasma gondii ENSG00000094841 ENSG00000102967 ENSG00000254550 PMC3198893__F5 One of the networks of genes strongly induced in dendritic cells but less so, unchanged, or suppressed in macrophages ENSG00000063978 ENSG00000155367 ENSG00000182944 ENSG00000185231 ENSG00000127191 PMC3198893__F4 One of the networks of genes commonly induced in both dendritic cells and macrophages when infected by bacteria, in both human and mouse ENSG00000188313 PMC3811010__F3 Target genes of CDX1 and CDX2, and the BMP/TGFB signaling pathway ENSG00000253293 ENSG00000058085 ENSG00000134982 ENSG00000120885 ENSG00000131096 ENSG00000136826 ENSG00000159788 ENSG00000100385 ENSG00000079112 ENSG00000170365 ENSG00000074181 ENSG00000115138 ENSG00000163017 ENSG00000113722 ENSG00000293532 ENSG00000161298 ENSG00000163515 ENSG00000078399 ENSG00000274473 ENSG00000109814 ENSG00000160180 ENSG00000169906 ENSG00000173258 ENSG00000132646 ENSG00000165376 ENSG00000143167 ENSG00000073737 ENSG00000165556 ENSG00000140564 ENSG00000090402 ENSG00000105329 ENSG00000089472 ENSG00000139567 ENSG00000278373 ENSG00000156574 ENSG00000120437 ENSG00000100146 ENSG00000163295 ENSG00000158747 ENSG00000118971 ENSG00000122859 ENSG00000070019 ENSG00000112242 ENSG00000095739 ENSG00000131142 ENSG00000128791 ENSG00000276051 ENSG00000124664 ENSG00000125968 ENSG00000172238 ENSG00000137673 ENSG00000115297 ENSG00000113070 ENSG00000136478 ENSG00000134363 ENSG00000168487 ENSG00000131910 ENSG00000135144 ENSG00000177606 ENSG00000204217 PMC8416724__F4 CD47/SIRPA pathway mediates cancer immune escape and immunotherapy ENSG00000198053 PMC6714138__F8 Schematic diagram showing the cardioprotective effects of YWPC on DOX‐induced cardiotoxicity ENSG00000105329 ENSG00000181019 ENSG00000171791 ENSG00000023909 ENSG00000079999 PMC4338835__F3 The catecholamine system in health and disease —Relation to tyrosine 3-monooxygenase and other catecholamine-synthesizing enzymes— ENSG00000123454 ENSG00000141744 ENSG00000116096 PMC6160678__F6 An comprehesive metabolomics and transcriptomics study to identify metabolic pathway alterations in CFG treatment of ovarian tumor-bearing mice in vivo ENSG00000115361 ENSG00000099194 ENSG00000122971 PMC7469327__F6 Drugs targeting inflammasome signaling in MS and EAE ENSG00000162711 ENSG00000115415 ENSG00000125538 ENSG00000091592 ENSG00000168610 PMC9165361__F1 Implication of 14-3-3ζ-BDNF pathway in long-lasting memory enhancement and the rescue from memory deficits ENSG00000169220 PMC6364417__F7 Pathways affected by the combined selected kinase inhibitors in BRAF mutant melanoma cells ENSG00000135446 PMC3528378__F3 Mechanism of muscle protein synthesis inhibition by GCs ENSG00000198793 PMC9455514__F4 Critical Roles of Polycomb Repressive Complexes in Transcription and Cancer ENSG00000156374 ENSG00000168283 ENSG00000169554 ENSG00000147162 ENSG00000134057 ENSG00000026508 ENSG00000118971 ENSG00000119681 ENSG00000115289 PMC5531360__F3 Possible interactions between signaling molecules ENSG00000110799 PMC7388835__F6 Gene interaction network map ENSG00000105722 ENSG00000115091 ENSG00000182180 ENSG00000123992 ENSG00000196504 ENSG00000105323 ENSG00000124920 ENSG00000100320 ENSG00000186575 ENSG00000120533 ENSG00000107854 ENSG00000163914 ENSG00000142599 ENSG00000185222 ENSG00000035141 ENSG00000179833 ENSG00000167264 PMC7388835__F5 Network diagram representing the regulatory effects with top consistency scores ENSG00000115415 ENSG00000269335 ENSG00000213341 PMC4076091__F7 GW1516 intervention inhibits progression of hepatic steatosis in mice ENSG00000186480 ENSG00000169710 ENSG00000124253 PMC6548416__F2 Impact of diet-derived signaling molecules on human cognition ENSG00000002330 ENSG00000138798 ENSG00000198793 ENSG00000177606 ENSG00000167371 ENSG00000169032 PMC8537973__F9 Network Pharmacology of Red Ginseng (Part I): Effects of Ginsenoside Rg5 at Physiological and Sub-Physiological Concentrations ENSG00000140992 ENSG00000265681 ENSG00000198918 ENSG00000133056 ENSG00000087074 ENSG00000197728 ENSG00000161970 ENSG00000092847 ENSG00000105647 ENSG00000108107 ENSG00000083845 ENSG00000161960 ENSG00000172809 ENSG00000128272 ENSG00000101255 ENSG00000184110 ENSG00000129824 ENSG00000185088 PMC7071696__F7 Mechanism graph of the regulatory network of miR-495/HOXC6/TGFB in the progression of OSCC ENSG00000197757 PMC6082538__F6 Cranberry-derived proanthocyanidins induce a differential transcriptomic response within Candida albicans urinary biofilms ENSG00000137078 ENSG00000039537 ENSG00000117298 ENSG00000100029 ENSG00000119125 PMC6082538__F4 Cranberry-derived proanthocyanidins induce a differential transcriptomic response within Candida albicans urinary biofilms ENSG00000069482 ENSG00000168803 ENSG00000163295 PMC6972508__F2 Mode of action of thalidomide and its derivatives in regulating host inflammatory response ENSG00000161405 ENSG00000125538 PMC4629506__F1 TLR and NFKB signaling disrupted by PID ENSG00000183735 ENSG00000134070 ENSG00000172936 ENSG00000157625 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC4046566__F2 Application of the algorithm to identify TNBC-associated genes ENSG00000275385 ENSG00000130294 ENSG00000122966 ENSG00000138083 ENSG00000198929 ENSG00000187741 ENSG00000171791 ENSG00000166851 ENSG00000138778 ENSG00000163141 ENSG00000008838 ENSG00000125686 ENSG00000107485 ENSG00000291608 PMC7803563__F1 Schematic model showing that the DEGs in the older melanoma patients by recurrence status converge at the Wnt signaling pathway ENSG00000125538 ENSG00000168036 ENSG00000073756 PMC11999469__F8 Connection of Nrf2, NFKB, NLRP3 Pathways and the mechanism of SA ENSG00000181019 ENSG00000100387 ENSG00000136869 ENSG00000023909 ENSG00000079999 PMC8327141__F4 The MCTS1 and DENR Proteins in Regulating the Mechanisms Associated with Malignant Cell Transformation ENSG00000291971 ENSG00000232119 PMC7368990__F6 Schematics of glycolysis, tricarboxylic acid cycle, and pentose phosphate pathway showing changes at the translational level of enzymes involved in the different steps ENSG00000180210 ENSG00000131473 ENSG00000130957 ENSG00000197713 ENSG00000153574 ENSG00000105953 ENSG00000078237 ENSG00000115419 ENSG00000062485 PMC7272692__F4 Mitotic/endocycle switch ENSG00000112977 ENSG00000123374 ENSG00000112742 ENSG00000276876 PMC4354340__F8 miR-4689 regulates EGFR signaling pathway ENSG00000146648 PMC9437264__F12 CGMP/Akt/GSK-3B signaling pathway on atrial natriuretic peptide secretion in rabbits with rapid atrial pacing ENSG00000096088 PMC10648128__F5 DEGs belonging to the gap junction signaling pathway in the hippocampus (magenta) and frontal cortex (red) of OXYS rats at PND3 and PND10 ENSG00000164879 ENSG00000213658 ENSG00000087842 PMC3508723__F8 Model of Tat/Beta-catenin interaction in astrocytes ENSG00000111537 ENSG00000168036 ENSG00000168646 PMC5259746__F3 Costunolide and dehydrocostuslactone combination treatment inhibit breast cancer by inducing cell cycle arrest and apoptosis through c-Myc/p53 and AKT/14-3-3 pathway ENSG00000110711 ENSG00000002330 ENSG00000179151 ENSG00000171791 ENSG00000127191 ENSG00000140443 ENSG00000135250 ENSG00000026103 PMC3574110__F4 Differential Effects of Drug Interventions and Dietary Lifestyle in Developing Type 2 Diabetes and Complications: A Systems Biology Analysis in LDLr−/− Mice ENSG00000110711 ENSG00000186340 ENSG00000063660 ENSG00000162772 ENSG00000116761 ENSG00000275544 ENSG00000087116 PMC10940631__F3 Compensatory relationship between the ubiquitin‒proteasome pathway and the autolysosome pathway ENSG00000177169 ENSG00000124762 PMC3356354__F8 High-Throughput Sequence Analysis of Turbot (Scophthalmus maximus) Transcriptome Using 454-Pyrosequencing for the Discovery of Antiviral Immune Genes ENSG00000104237 ENSG00000170458 ENSG00000198793 ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC3926670__F4 Enriched pathway of the target gene union of radiation-response miRNAs ENSG00000002330 ENSG00000198793 ENSG00000123374 ENSG00000171791 ENSG00000167034 PMC3356354__F9 High-Throughput Sequence Analysis of Turbot (Scophthalmus maximus) Transcriptome Using 454-Pyrosequencing for the Discovery of Antiviral Immune Genes ENSG00000177455 ENSG00000095585 ENSG00000010671 PMC5643010__F2 Janus kinase antagonists and other novel small molecules for the treatment of Crohn’s disease PMC4152115__F5 Plausible molecular mechanism of migration and osteogenic differentiation of BMSCs by Ce through Smad1/5/8 signaling pathway ENSG00000170365 ENSG00000204217 PMC12152576__F2 Contribution of type-I IFN-mediated neuroinflammation to Parkinson's disease progression ENSG00000213928 ENSG00000164430 ENSG00000105397 ENSG00000115415 ENSG00000276561 ENSG00000142166 PMC10216802__F2 LPS (TLR4)-mediated inflammation and its interplay with RhoA activation and the downstream ROCK signaling pathways ENSG00000136869 ENSG00000067900 PMC6545862__F1 A potential nuclear factorKB activation pathway obtained by RNA-sequencing analysis in canine diffuse large B-cell lymphomas ENSG00000105369 ENSG00000100906 ENSG00000291971 ENSG00000198793 ENSG00000269335 ENSG00000173039 ENSG00000010671 ENSG00000177455 ENSG00000095585 ENSG00000239732 ENSG00000118503 ENSG00000197943 ENSG00000172936 ENSG00000175104 ENSG00000198286 PMC4163606__F1 LIF signaling and post-translational modifications of some stemness transcription factors ENSG00000128342 ENSG00000116030 ENSG00000168610 PMC2536868__F7 Pathways for major lipid metabolism ENSG00000131473 ENSG00000160752 ENSG00000134824 ENSG00000095321 ENSG00000149485 ENSG00000173599 ENSG00000104549 ENSG00000285482 ENSG00000160216 ENSG00000026103 PMC9355246__F2 Regulation of skin homeostasis, repair and the pathogenesis of skin diseases by spatiotemporal activation of epidermal mTOR signaling ENSG00000177169 ENSG00000198793 ENSG00000118515 ENSG00000155792 ENSG00000167965 PMC5652964__F6 Proposed working model of ZZR on the Hedgehog signaling pathway-mediated MDR in colorectal cancer cells ENSG00000106571 ENSG00000128602 PMC6562634__F3 Schematic model of regulation of the Hippo pathway by numerous signaling pathways in cancer ENSG00000186575 ENSG00000134569 ENSG00000149269 ENSG00000030304 ENSG00000150457 ENSG00000131023 PMC6562634__F2 The Hippo pathway drives fibrosis across the organs ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC6562634__F1 The Hippo pathway in the pathogenesis of tissue fibrosis ENSG00000125482 ENSG00000019549 ENSG00000179431 ENSG00000150457 ENSG00000163501 ENSG00000131023 PMC11245093__F4 Genomics-based reconstruction of pathways involved in the utilization of monosaccharide derivatives ENSG00000197713 ENSG00000198951 ENSG00000111816 ENSG00000135517 PMC5025072__F5 Network-Based Data Integration Approach to Support Drug Repurposing and Multi-Target Therapies in Triple Negative Breast Cancer ENSG00000136158 ENSG00000274211 ENSG00000213928 ENSG00000090534 ENSG00000005339 ENSG00000114737 ENSG00000137193 ENSG00000142273 ENSG00000121879 ENSG00000100485 ENSG00000166068 ENSG00000179295 ENSG00000117020 ENSG00000111537 ENSG00000110395 ENSG00000164056 ENSG00000115415 ENSG00000167941 ENSG00000136997 ENSG00000164136 ENSG00000115145 ENSG00000187678 PMC6695454__F3 Therapies targeting p53 functions ENSG00000274089 PMC3504715__F8 Cytokine-induced CITED2/MYC/E2F3/p21CIP1signaling in lung cancer ENSG00000112242 ENSG00000163235 ENSG00000136997 ENSG00000185591 ENSG00000146648 PMC6562634__F4 YAP/TAZ-mediated regulatory networks in cancer ENSG00000145604 ENSG00000167601 ENSG00000066468 ENSG00000125398 ENSG00000145147 ENSG00000163430 ENSG00000160867 ENSG00000121058 ENSG00000019549 ENSG00000077782 ENSG00000089225 ENSG00000137801 PMC8465517__F2 Signaling Overlap between the Golgi Stress Response and Cysteine Metabolism in Huntington’s Disease ENSG00000128272 ENSG00000144895 ENSG00000168374 ENSG00000107175 PMC3844829__F3 Metacore™ apoptosis signaling pathway relating to mitochondrial proteins ENSG00000002330 ENSG00000135116 ENSG00000026103 PMC3844829__F2 Metacore™ apoptosis signaling pathway relating to TNF receptors, NFkB and BCL-2 antiapoptotic family genes ENSG00000104689 ENSG00000146072 ENSG00000168040 PMC1323499__F1 New Approaches to Vaccine Adjuvants: Inhibiting the Inhibitor ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC8465517__F4 Signaling Overlap between the Golgi Stress Response and Cysteine Metabolism in Huntington’s Disease ENSG00000128272 ENSG00000144895 ENSG00000185591 PMC3844829__F4 Metacore™ apoptosis signaling pathway relating to caspase activation ENSG00000102104 ENSG00000084774 PMC5908886__F3 Peroxisome proliferator-activated receptor gamma (PPARG) activation ENSG00000002330 ENSG00000168036 PMC5908886__F4 Crosstalk Between Peroxisome Proliferator-Activated Receptor Gamma and the Canonical WNT/Beta-Catenin Pathway in Chronic Inflammation and Oxidative Stress During Carcinogenesis ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC9324774__F1 Therapeutic Potential of Carnosine as an Antidote against Drug-Induced Cardiotoxicity and Neurotoxicity: Focus on Nrf2 Pathway ENSG00000100387 ENSG00000079999 PMC6003829__F8 R-loops cause genomic instability in Wiskott-Aldrich syndrome Thelper lymphocytes ENSG00000136807 ENSG00000149311 PMC11879902__F4 Diagram of glycolytic signaling pathway in senescent cells ENSG00000169047 ENSG00000136997 ENSG00000078237 ENSG00000159399 PMC11879902__F3 Aerobic glycolysis in tumor cells ENSG00000176692 ENSG00000078237 ENSG00000159399 PMC12246557__F5 Type I, type II, and type III interferon signaling and IFN‐I pathway‐related inhibitors ENSG00000213928 ENSG00000105397 ENSG00000115415 PMC5826217__F1 Insulin/IGF-1/PI3K/Akt/GSK3B/tau signaling ENSG00000169047 ENSG00000140443 PMC9275048__F2 Network analysis of synovial RNA sequencing identifies gene-gene interactions predictive of response in rheumatoid arthritis ENSG00000151726 ENSG00000281324 ENSG00000167393 ENSG00000100485 ENSG00000172037 ENSG00000145431 ENSG00000053747 ENSG00000041982 ENSG00000108821 ENSG00000159128 ENSG00000119535 ENSG00000099194 ENSG00000132170 ENSG00000120063 ENSG00000138193 ENSG00000170962 ENSG00000118785 ENSG00000140285 ENSG00000067191 ENSG00000004975 ENSG00000291971 ENSG00000050748 ENSG00000150093 ENSG00000105647 ENSG00000099942 ENSG00000112715 ENSG00000104332 ENSG00000121879 ENSG00000137801 ENSG00000142166 ENSG00000049130 ENSG00000145623 ENSG00000129946 ENSG00000124181 ENSG00000259207 ENSG00000269335 ENSG00000174804 ENSG00000106483 ENSG00000110324 ENSG00000169242 ENSG00000137841 ENSG00000291420 ENSG00000161714 ENSG00000117020 ENSG00000081913 ENSG00000113296 ENSG00000159346 ENSG00000243646 ENSG00000285070 ENSG00000161202 ENSG00000110799 ENSG00000141564 ENSG00000163737 ENSG00000149781 ENSG00000213949 ENSG00000074181 ENSG00000167941 ENSG00000197943 ENSG00000077782 ENSG00000292332 ENSG00000123983 ENSG00000135929 ENSG00000107404 ENSG00000147168 ENSG00000137070 ENSG00000027697 ENSG00000213341 ENSG00000204673 ENSG00000171914 ENSG00000026508 ENSG00000096717 ENSG00000146648 ENSG00000049323 ENSG00000135218 ENSG00000070831 ENSG00000198793 ENSG00000149782 ENSG00000196396 ENSG00000064300 ENSG00000169231 ENSG00000185518 ENSG00000136457 ENSG00000105664 ENSG00000186340 ENSG00000111186 ENSG00000131724 ENSG00000137834 ENSG00000171105 ENSG00000104365 ENSG00000167114 ENSG00000134871 ENSG00000160691 ENSG00000130304 ENSG00000167535 ENSG00000184371 ENSG00000137076 ENSG00000135424 ENSG00000171608 PMC5922346__F6 Tumor cell death after electrotransfer of plasmid DNA is associated with cytosolic DNA sensor upregulation ENSG00000183735 ENSG00000105397 ENSG00000168404 PMC8763513__F10 3B,23-Dihydroxy-12-ene-28-ursolic Acid Isolated from Cyclocarya paliurus Alleviates NLRP3 Inflammasome-Mediated Gout via PI3K-AKT-mTOR-Dependent Autophagy ENSG00000162711 ENSG00000198793 ENSG00000265972 PMC12246557__F3 Nucleic acid sensors and downstream signaling pathways induce type I IFN production ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 ENSG00000184216 PMC3471537__F1 HER2 activation ENSG00000146648 PMC11996656__F3 Signaling pathways involved in the pathophysiological development of OA, along with their corresponding targeted therapeutic drugs ENSG00000278718 ENSG00000162711 ENSG00000147162 ENSG00000198793 ENSG00000265972 ENSG00000155313 ENSG00000125347 ENSG00000154451 ENSG00000115415 ENSG00000134326 ENSG00000189403 ENSG00000136869 ENSG00000172936 ENSG00000175104 ENSG00000275031 PMC11996656__F2 Pyroptosis in OA pathogenesis ENSG00000278718 ENSG00000162711 ENSG00000189403 PMC11996656__F1 Classical, non-classical, and other pathways involved in pyroptosis ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC2180420__F9 Co-coculture system reveals the involvement of intercellular pathways as mediators of the lutropin receptor (LHR)-stimulated ERK1/2 phosphorylation in Leydig cells ENSG00000010810 ENSG00000146648 PMC6026536__F1 Reactions and enzymes of proline metabolism in higher organisms ENSG00000100033 PMC3087811__F8 Schematic model for the role of TGFB signaling pathways in iTreg and Th17 cell development ENSG00000049768 PMC4702573__F6 Simplified model for CCC DNA synthesis and innate immune induction by HBV in AML12HBV10 cells ENSG00000183735 ENSG00000164430 PMC2943859__F9 TNF-R1 signaling pathways ENSG00000102871 ENSG00000056558 ENSG00000099860 ENSG00000168040 ENSG00000127191 PMC8778078__F3 Inflammation as A Precursor of Atherothrombosis, Diabetes and Early Vascular Aging ENSG00000162711 ENSG00000150782 ENSG00000125538 PMC2949723__F3 Eicosanoid signaling pathway from Ingenuity Pathway Analysis software ENSG00000132965 ENSG00000161905 ENSG00000275565 PMC8755999__F1 Congenital Adrenal Hyperplasia—Current Insights in Pathophysiology, Diagnostics, and Management ENSG00000277893 ENSG00000161513 ENSG00000203859 ENSG00000179142 ENSG00000137714 ENSG00000127948 PMC5350732__F3 Gene transcripts associated with sensitivity to gefitinib and EGFR and/or head and neck cancer, identified from the genome‐wide statistical analysis, followed by pathway analysis ENSG00000100234 ENSG00000125266 ENSG00000121552 ENSG00000196754 ENSG00000120690 ENSG00000058085 ENSG00000085117 ENSG00000109321 ENSG00000198561 ENSG00000173039 ENSG00000166147 ENSG00000068028 ENSG00000057149 ENSG00000167656 ENSG00000163435 ENSG00000163235 ENSG00000010810 ENSG00000146648 ENSG00000163660 ENSG00000186832 PMC9084610__F1 COVID-19 Infection During Pregnancy Induces Differential Gene Expression in Human Cord Blood Cells From Term Neonates ENSG00000150907 ENSG00000137845 ENSG00000160741 PMC4133771__F1 Possible signaling of G ENSG00000168036 ENSG00000105723 ENSG00000075213 PMC6378068__F5 GPL pathway constructed in this study ENSG00000002330 ENSG00000102871 ENSG00000138798 ENSG00000146648 ENSG00000132341 PMC4768116__F2 Activation of nuclear factorKB: Canonical and non-canonical pathways ENSG00000104856 ENSG00000186716 ENSG00000173039 ENSG00000136869 PMC8517843__F3 ADAMs family in kidney physiology and pathology ENSG00000161921 ENSG00000130234 ENSG00000086991 ENSG00000146648 PMC5665066__F1 PolyI:C induces tumor necroptosis via the TLR3 -TICAM1 pathway ENSG00000183735 ENSG00000088888 ENSG00000168404 ENSG00000127666 ENSG00000164342 PMC4745409__F2 Pathways involved in internalization and sensing of dsDNA ENSG00000183735 ENSG00000239732 ENSG00000088888 ENSG00000163568 ENSG00000186716 ENSG00000189403 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 PMC6760864__F3 New insights into cytoskeletal remodeling during platelet production ENSG00000070831 PMC2480606__F2 NFKB pathway in skeletal muscles ENSG00000100811 PMC11807217__F8 Anaerobic metabolism promotes breast cancer survival via Histone-3 Lysine-18 lactylation mediating PPARD axis ENSG00000135446 ENSG00000105810 PMC9024148__F6 Multi-Omics Characterizes the Effects and Mechanisms of CD1d in Nonalcoholic Fatty Liver Disease Development ENSG00000110244 ENSG00000134824 ENSG00000148926 ENSG00000140505 ENSG00000113448 PMC2816026__F7 Met signal transduction exploited by InlB from L ENSG00000110395 ENSG00000010810 PMC8112564__F6 ANKRD22 enhances breast cancer cell malignancy by activating the Wnt/Beta-catenin pathway via modulating NuSAP1 expression ENSG00000137804 ENSG00000152766 ENSG00000168036 PMC2480606__F1 An outline of major signaling pathways leading to NFKB activation ENSG00000104856 ENSG00000149311 ENSG00000102871 ENSG00000172936 ENSG00000111321 ENSG00000175104 ENSG00000127191 PMC8607246__F2 A novel potentially transforming somatic mutation in CSF2RB gene in breast cancer ENSG00000198793 ENSG00000164399 ENSG00000292357 ENSG00000168610 PMC8287856__F1 Dissecting the Role of Mesenchymal Stem Cells in Idiopathic Pulmonary Fibrosis: Cause or Solution ENSG00000137673 ENSG00000198793 ENSG00000168036 ENSG00000164690 ENSG00000154096 PMC5003773__F1 Empowering Regulatory T Cells in Autoimmunity ENSG00000168214 ENSG00000150907 ENSG00000049768 PMC3035137__F2 Effects of Hfe deficiency and the associated low hepcidin and intracellular iron levels on macrophage TLR4 signaling ENSG00000010704 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC8777499__F1 Serine and one-carbon metabolisms bring new therapeutic venues in prostate cancer ENSG00000284320 ENSG00000065911 ENSG00000100714 ENSG00000092621 ENSG00000135069 ENSG00000163738 ENSG00000146733 PMC7767764__F1 Lipofuscin and drusen in the RPE ENSG00000175054 ENSG00000197713 ENSG00000080511 PMC9050318__F6 Mechanism of Osthole in the Treatment of Gastric Cancer Based on Network Pharmacology and Molecular Docking Technology ENSG00000054116 PMC8870390__F1 Precision Targets for Intercepting the Lethal Progression of Prostate Cancer: Potential Avenues for Personalized Therapy ENSG00000168610 PMC6086630__F7 Network mappings were Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway of HOXA3 co-expression genes in NSCLC ENSG00000109819 ENSG00000117020 ENSG00000106571 ENSG00000170962 ENSG00000146648 ENSG00000167034 ENSG00000105287 PMC3903560__F7 Ingenuity pathways analysis ENSG00000204397 ENSG00000066294 ENSG00000135077 ENSG00000128284 ENSG00000050344 ENSG00000095015 ENSG00000137496 PMC8903057__F4 Diverging effects of LMW-HA and HMW-HA in neurodegeneration and AD ENSG00000026508 ENSG00000136869 PMC7934812__F1 Toll-like receptor 4 (TLR4) antagonists as potential therapeutics for intestinal inflammation ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000150455 ENSG00000175104 PMC3613823__F8 The proposed therapeutic mechanism of caspase-7 ablation in ADRP T17M RHO retinas ENSG00000128272 ENSG00000198793 ENSG00000163914 ENSG00000185010 PMC4839461__F1 Schematic overview of de novo and salvage dNTP biosynthetic pathways and the mechanism of action of dCK-dependent nucleoside analog prodrugs ENSG00000196839 ENSG00000291814 PMC3193407__F1 NFKB activation by the canonical pathway ENSG00000138798 ENSG00000198670 ENSG00000146648 PMC7934812__F2 Toll-like receptor 4 (TLR4) antagonists as potential therapeutics for intestinal inflammation ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 PMC12116171__F3 Up-regulated circadian rhythm pathway and phenological effects of cul4 mutant ENSG00000163435 ENSG00000203783 ENSG00000131188 PMC5805723__F7 Oncogenic cooperation of BRAF V600E and TERT promoter mutations ENSG00000136997 ENSG00000164362 PMC10372325__F6 Transcriptomic and physiological analyses reveal temporal changes contributing to the delayed healing response to arterial injury in diabetic rats ENSG00000116044 ENSG00000285109 ENSG00000148400 ENSG00000130522 ENSG00000168036 ENSG00000049768 ENSG00000125347 ENSG00000196628 ENSG00000245848 ENSG00000172216 ENSG00000156127 ENSG00000167182 ENSG00000140464 ENSG00000108312 PMC8879755__F2 Innate Immunity in Mucopolysaccharide Diseases ENSG00000162711 ENSG00000125538 ENSG00000136869 ENSG00000131095 PMC10217168__F14 Graphical summary of the protective effect of Lactiplantibacillus plantarum Lac16 against enterohemorrhagic E ENSG00000168036 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000168646 ENSG00000155760 PMC5487892__F3 DNA substrates and protein factors required for S-phase checkpoint activation ENSG00000276618 ENSG00000260314 ENSG00000138346 ENSG00000132646 ENSG00000177084 ENSG00000143971 ENSG00000093009 PMC5645256__F2 Association between expression of cell cycle proteins in NETs according to pathway ENSG00000135446 ENSG00000123374 ENSG00000105810 ENSG00000124762 PMC8509327__SF3 Non-Canonical Wnt Signalling Pathways in Bone Biology ENSG00000087095 ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000198793 ENSG00000168036 ENSG00000175104 PMC5443707__F1 Coordination of DNA Single Strand Break Repair ENSG00000143799 ENSG00000105486 ENSG00000132646 PMC4800996__F2 Serine biosynthesis and utilization ENSG00000284320 ENSG00000092621 ENSG00000135069 ENSG00000146733 ENSG00000178445 PMC8509327__SF2 Non-Canonical Wnt Signalling Pathways in Bone Biology ENSG00000169071 ENSG00000070831 PMC8509327__SF1 Non-Canonical Wnt Signalling Pathways in Bone Biology ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3913524__F1 The PI3K/Akt/mTOR pathway substrates and associated cellular functions ENSG00000198793 ENSG00000164327 PMC3607121__F1 Androgen deprivation promotes intratumoral synthesis of dihydrotestosterone from androgen metabolites in prostate cancer ENSG00000086696 ENSG00000151632 ENSG00000196620 ENSG00000203857 ENSG00000187134 PMC10525295__F1 Review of the Relationship between the Immune Response, Inflammation, Oxidative Stress, and the Pathogenesis of Sickle Cell Anaemia ENSG00000099194 PMC3890879__F8 Model of mevalonate and Hippo pathways regulating YAP-controlled RHAMM transcription and cancer cell motility ENSG00000150457 ENSG00000131023 PMC8122612__F4 Salivary Proteome Changes in Response to Acute Psychological Stress Due to an Oral Exam Simulation in University Students: Effect of an Olfactory Stimulus ENSG00000171195 ENSG00000132465 ENSG00000240038 ENSG00000291998 ENSG00000183979 ENSG00000206177 ENSG00000169605 ENSG00000008323 ENSG00000177599 ENSG00000165471 ENSG00000163631 PMC8734249__F2 CD70-CD27 axis in oncology: the new kids on the block ENSG00000139193 ENSG00000026508 PMC8734249__F1 CD70-CD27 axis in oncology: the new kids on the block ENSG00000139193 ENSG00000127191 PMC7691336__F9 Enhancing calmodulin binding to cardiac ryanodine receptor completely inhibits pressure-overload induced hypertrophic signaling ENSG00000285109 ENSG00000198626 ENSG00000285485 PMC3461086__F3 Canonical Wnt signaling pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC11755046__F9 Synergy between the LINC01419/miR-8070/RAD51AP1 axis and HBV in HBV-associated HCC ENSG00000111247 PMC8628653__F1 Disruption of the Diurnal Cortisol Hormone Pattern by Pesticide Use in a Longitudinal Study of Farmers in Thailand ENSG00000179142 PMC3461086__F4 Simplified diagram of signal pathway convergence at downstream nuclear targets ENSG00000125398 PMC7327974__F3 A) A model depicting the regulation of apoptosis through the TNF pathway and B) Simulation of the signaling process ENSG00000002330 ENSG00000138798 ENSG00000198793 ENSG00000128052 ENSG00000112715 ENSG00000146648 PMC3016890__F1 The p38MAPKsignalling pathway ENSG00000112576 ENSG00000070831 ENSG00000115415 ENSG00000183486 ENSG00000081189 PMC6535827__F3 Neuroprotective effects of resveratrol in AD PMC8935233__F8 PROX1 promotes breast cancer invasion and metastasis through WNT/Beta-catenin pathway via interacting with hnRNPK ENSG00000165119 ENSG00000134982 ENSG00000015285 ENSG00000183579 ENSG00000168036 ENSG00000117707 PMC6708252__F1 Interactions between VHL, HIF and the NFKB signaling pathway ENSG00000134086 ENSG00000138798 PMC5458139__F5 Mutational Signatures in Breast Cancer: The Problem at the DNA Level PMC5912715__F3 Local and systemic inflammatory lipid profiling in a rat model of osteoarthritis with metabolic dysregulation ENSG00000197465 ENSG00000283887 ENSG00000226275 ENSG00000095303 ENSG00000124212 ENSG00000073756 PMC7186480__F7 Possible cross-talk of IFNs and the AIM2 inflammasome pathways in AMs from TB patients (AMTB) modulated by M ENSG00000111537 ENSG00000170458 ENSG00000115415 ENSG00000163568 ENSG00000172936 ENSG00000136869 ENSG00000125347 ENSG00000175104 PMC7363763__F2 Endothelial cilium regulates various signaling pathways involved in the vascular barrier, such as HH and Notch pathways ENSG00000143147 ENSG00000128917 ENSG00000148400 ENSG00000164690 ENSG00000128602 PMC4463188__F7 MEL-18 loss mediates estrogen receptor–A downregulation and hormone independence ENSG00000079387 ENSG00000198901 ENSG00000185591 PMC1766317__F5 Model: A similar CARMA-Bcl10-MALT1 signaling pathway mediates NFKB activation in response to antigen receptor stimulation in lymphocytes and AT1R stimulation in liver cells ENSG00000125538 PMC5655777__F2 This schematic diagram depicts the signaling pathways that possibly drive BAVM pathology PMC4333762__F3 PRb/E2F pathway regulates cell cycle progression ENSG00000112242 ENSG00000165891 ENSG00000135446 ENSG00000123374 ENSG00000133740 ENSG00000205250 ENSG00000282899 PMC6649605__F8 Proposed mechanism by which gremlin regulates EMT and ECM protein expression in LECs ENSG00000170365 PMC3589762__F2 Pathways regulating intestinal sterol absorption and homeostasis ENSG00000138075 ENSG00000135218 ENSG00000138823 ENSG00000015520 ENSG00000120437 PMC6284860__F1 p53 limits B cell receptor (BCR) signalling: a new role for miR-34a and FOXP1 ENSG00000177455 ENSG00000095585 ENSG00000186716 ENSG00000136997 ENSG00000197943 ENSG00000010671 PMC6511523__F4 Molecular biological features in the adrenal gland of Hatano rats ENSG00000185231 PMC2846156__F3 Therapeutic Targeting of Toll-Like Receptors for Infectious and Inflammatory Diseases and Cancer ENSG00000183735 ENSG00000172005 ENSG00000136869 ENSG00000131323 ENSG00000168040 ENSG00000175104 ENSG00000276561 ENSG00000010671 PMC9058298__F6 Heterogeneous nuclear ribonucleoprotein K promotes the progression of lung cancer by inhibiting the p53‐dependent signaling pathway ENSG00000149311 ENSG00000175054 ENSG00000165119 PMC8745478__F2 P38 MAPK Components and Modulators as Biomarkers and Molecular Targets in Cancer ENSG00000101224 ENSG00000179348 PMC3989185__F8 Stiffness-Activated GEF-H1 Expression Exacerbates LPS-Induced Lung Inflammation ENSG00000163914 PMC8368762__F1 Pyroptosis in cardiovascular pathologies: Role of noncoding RNAs ENSG00000162711 ENSG00000150782 ENSG00000137275 ENSG00000137033 ENSG00000102871 ENSG00000167468 ENSG00000198793 ENSG00000168040 ENSG00000168404 ENSG00000285379 ENSG00000026103 PMC9653341__F3 Immune response associated with ischemia and reperfusion injury during organ transplantation ENSG00000102962 ENSG00000148400 ENSG00000102970 PMC5713646__F1 Chemical synthesis of n-butyraldehyde from petrochemical feedstock PMC5126119__F2 TLR-4/LPS signaling pathway activated by LPS in ALD ENSG00000170458 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC4146087__F5 Mechanisms of extracellular signal-regulated kinase/cAMP response element-binding protein/brain-derived neurotrophic factor signal transduction pathway in depressive disorder ENSG00000157005 PMC4146087__F1 Mechanisms of extracellular signal-regulated kinase/cAMP response element-binding protein/brain-derived neurotrophic factor signal transduction pathway in depressive disorder ENSG00000169291 PMC4146087__F2 Interaction of drug and signaling pathway in relevance to depression.Sex steroid hormones serve as an example PMC11004986__F8 Autotaxin and lysophosphatidic acid deficiencies on depression-like behaviors in mice exposed to chronic unpredictable mild stress ENSG00000198670 ENSG00000102003 PMC6131826__F6 Phosphatidylinositol signaling pathway ENSG00000124102 ENSG00000167900 PMC2737000__F4 TNF-induced NFKB and apoptosis pathways ENSG00000104365 ENSG00000110330 ENSG00000102871 ENSG00000070770 ENSG00000120889 ENSG00000173039 ENSG00000168040 ENSG00000258643 ENSG00000127191 ENSG00000026103 PMC5449392__F6 Proposed role of ARRB1, CALM3, FLNA and HTT in OSCC ENSG00000038382 ENSG00000006451 ENSG00000197386 PMC4382460__F2 IL-10 signaling pathways in normal and abnormal conditions ENSG00000105397 ENSG00000168610 PMC5382327__F1 Fish retinoic acid‐inducible gene I (RIG‐I) ‐like receptor (RLR) ‐mediated signalling pathways in response to viral and bacterial infections ENSG00000183735 ENSG00000088888 ENSG00000134321 ENSG00000167207 ENSG00000131323 ENSG00000276561 PMC8431390__F1 Nucleic Acid Sensing in the Tumor Vasculature ENSG00000164430 ENSG00000088888 PMC5352102__F2 Sirtuins in glucose and lipid metabolism ENSG00000077463 ENSG00000119912 ENSG00000089163 PMC5839385__F4 TAM pathway signaling in innate immune cells ENSG00000115415 ENSG00000177606 ENSG00000172005 ENSG00000172936 ENSG00000131323 ENSG00000175104 PMC4770763__F3 Subpathway-GMir: identifying miRNA-mediated metabolic subpathways by integrating condition-specific genes, microRNAs, and pathway topologies ENSG00000175535 ENSG00000108515 ENSG00000077044 ENSG00000148344 ENSG00000164708 ENSG00000186281 ENSG00000164294 PMC7309569__F3 The dolichol-linked oligosaccharide (DLO) biosynthesis pathway ENSG00000033011 ENSG00000088035 ENSG00000214160 PMC11665856__F7 A working model of PFOA stimulation of lung cancer metastasis ENSG00000291971 ENSG00000089159 PMC9337267__F1 Targeting strategies in the treatment of fumarate hydratase deficient renal cell carcinoma ENSG00000146648 ENSG00000115419 ENSG00000079999 PMC4380746__F1 Compstatin: a C3-targeted complement inhibitor reaching its prime for bedside intervention ENSG00000186716 ENSG00000203710 ENSG00000197405 ENSG00000117322 ENSG00000236625 ENSG00000167419 PMC6500672__F5 Putative suppressive pathway of Pj-ME in displaying its anti-inflammatory response ENSG00000291971 ENSG00000172936 ENSG00000136869 ENSG00000168610 PMC6471124__F1 The MEK5–extracellular signal-regulated kinase 5 (ERK5) pathway with activators and downstream effectors ENSG00000125538 ENSG00000168610 ENSG00000140464 PMC6882186__F10 Proposed pathways for polysaccharide biosynthesis in Dendrobium moniliforme ENSG00000112699 PMC2737000__F6 Androgen receptor pathway ENSG00000118495 ENSG00000095303 PMC4320664__F3 Drug targets downstream of receptor tyrosine kinases involved in synovial sarcoma (RTK) ENSG00000002330 ENSG00000174989 ENSG00000143507 ENSG00000106070 ENSG00000198793 ENSG00000169047 ENSG00000164327 ENSG00000171791 ENSG00000140443 PMC2737000__F5 Arachidonic acid metabolism pathway ENSG00000107404 ENSG00000134057 ENSG00000095303 ENSG00000221869 ENSG00000275565 ENSG00000073756 ENSG00000127472 ENSG00000005469 PMC5123387__F24 (Abstract P2) ENSG00000163235 ENSG00000163914 ENSG00000167074 PMC3367986__F2 Comparative Genomic Analysis of Soybean Flowering Genes ENSG00000163435 ENSG00000102034 ENSG00000006712 ENSG00000100842 ENSG00000179632 ENSG00000203783 ENSG00000131188 ENSG00000135097 PMC7865241__F7 Mechanistic scheme summarizing the anti-inflammatory effect of KMU-1170 ENSG00000162711 ENSG00000125538 ENSG00000172936 ENSG00000136869 PMC3104484__F5 Interplay between Wnt, Nurr1 and En1 signaling in vitro and in vivo ENSG00000163064 ENSG00000168036 PMC9666723__F8 Digital gene expression profiling of the transcriptional response to Sclerotinia sclerotiorum and its antagonistic bacterium Bacillus amyloliquefaciens in soybean ENSG00000101751 ENSG00000177971 ENSG00000145912 ENSG00000070814 ENSG00000241945 ENSG00000130826 ENSG00000262788 ENSG00000136718 ENSG00000291996 ENSG00000011260 ENSG00000101361 ENSG00000169251 ENSG00000041802 ENSG00000126749 ENSG00000185721 ENSG00000108651 ENSG00000165733 ENSG00000141101 ENSG00000055044 ENSG00000166169 ENSG00000132341 PMC8946083__F7 In Silico Analysis of Ion Channels and Their Correlation with Epithelial to Mesenchymal Transition in Breast Cancer ENSG00000152661 ENSG00000070831 ENSG00000011021 ENSG00000291971 ENSG00000125388 ENSG00000177807 ENSG00000150093 ENSG00000109738 ENSG00000124762 ENSG00000178084 ENSG00000105642 ENSG00000176884 ENSG00000148408 ENSG00000144935 ENSG00000177606 ENSG00000136997 ENSG00000137672 ENSG00000121743 ENSG00000146648 ENSG00000107147 PMC7177247__F8 CBD blocks the IL-1B/IL-1RI/Beta-catenin pathway and induces an epithelial phenotype ENSG00000023445 ENSG00000125968 PMC7260729__F8 RAP2.3 negatively regulates nitric oxide biosynthesis and related responses through a rheostat-like mechanism in Arabidopsis ENSG00000131480 PMC6116402__F2 Highly connected networks built using reperfusion-upregulated mRNAs coding for proteins known to interact with human proteins ENSG00000128016 ENSG00000259207 ENSG00000011422 ENSG00000177606 ENSG00000087074 ENSG00000162772 ENSG00000179348 PMC6365711__F10 miRNA-223 may be an anticancer gene in NSCLC through the PI3K/AKT pathway by targeting EGFR ENSG00000146648 PMC7764608__F5 NF-ĸB signaling pathway ENSG00000105369 ENSG00000007312 ENSG00000137193 ENSG00000171791 ENSG00000168610 ENSG00000292210 ENSG00000186716 ENSG00000136997 ENSG00000026508 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000198286 ENSG00000127074 PMC4288116__F4 Schematic illustrating the effect of p53 alteration on apoptotic pathway in basal-like breast cancer cells ENSG00000100906 ENSG00000102871 ENSG00000168040 ENSG00000184216 PMC4948960__F6 Pathway analysis of network signaling of some of the identified proteins as represented in the ingenuity pathway analysis database ENSG00000245848 ENSG00000070444 ENSG00000128016 ENSG00000147862 ENSG00000159216 ENSG00000073060 ENSG00000123933 ENSG00000005102 ENSG00000213347 ENSG00000158050 PMC5959262__F8 The protective mechanism of curcumin by the UPR-Nrf2 pathway after DAI ENSG00000128272 ENSG00000079999 PMC8461142__F1 Aryl hydrocarbon receptor (AHR) functions in infectious and sterile inflammation and NAD+-dependent metabolic adaptation ENSG00000105835 ENSG00000123572 ENSG00000096717 ENSG00000142082 PMC8218021__F3 Cross-Links of Endoplasmic Reticulum Stress, Autophagy, and Neurodegeneration in Parkinson’s Disease ENSG00000152348 ENSG00000188554 ENSG00000128272 ENSG00000150907 ENSG00000144848 ENSG00000171791 ENSG00000145782 ENSG00000127191 ENSG00000057663 PMC3080858__F6 PDP-1 Links the TGFB and IIS Pathways to Regulate Longevity, Development, and Metabolism ENSG00000157933 PMC9189345__F2 Research progress of endothelial‐mesenchymal transition in diabetic kidney disease ENSG00000145321 ENSG00000168036 ENSG00000164690 ENSG00000128602 PMC8430824__F1 Ferroptosis and Synthetic Lethality Strategies ENSG00000168003 ENSG00000135423 ENSG00000151012 ENSG00000197635 ENSG00000078668 ENSG00000167468 ENSG00000124762 PMC9189345__F1 Research progress of endothelial‐mesenchymal transition in diabetic kidney disease ENSG00000134982 ENSG00000168036 PMC9404924__F2 Potential Implications of Hydrogen Sulfide in Aging and Age-Related Diseases through the Lens of Mitohormesis ENSG00000102385 ENSG00000158828 ENSG00000171109 PMC9564314__F7 Emergence of MUC1 in Mammals for Adaptation of Barrier Epithelia ENSG00000168610 ENSG00000116649 PMC6249032__F2 Overview of Cdc5 functions in key cell cycle pathways ENSG00000070831 ENSG00000136425 PMC9564314__F5 Emergence of MUC1 in Mammals for Adaptation of Barrier Epithelia ENSG00000291971 ENSG00000136997 ENSG00000168036 ENSG00000146648 ENSG00000116649 ENSG00000196628 PMC2652867__F1 PML regulon model is used to explain the effects of the PML protein and PML nuclear bodies on survival signaling as described in the text ENSG00000145604 ENSG00000198793 ENSG00000140464 PMC4249369__F1 Pantothenate and coenzyme A biosynthetic pathway ENSG00000152782 ENSG00000273494 ENSG00000120137 ENSG00000068120 PMC2857326__F7 TGFB induces apoptosis in human B cells via transcriptional regulation of BIK and BCL-XL ENSG00000100290 ENSG00000186716 ENSG00000168040 ENSG00000026103 PMC6662984__F1 A2-3-sialyllactose showing PDB numbering ENSG00000039537 ENSG00000244731 PMC5825082__F7 Dysregulation of the IFN-Gamma-STAT1 signaling pathway in a cell line model of large granular lymphocyte leukemia ENSG00000115415 ENSG00000125347 ENSG00000168610 PMC9564314__F9 Emergence of MUC1 in Mammals for Adaptation of Barrier Epithelia ENSG00000291971 ENSG00000146648 PMC3973133__F6 Schematic showing actin cytoskeleton signaling pathways in adult hippocampal spines (see ) and the proposed mechanisms by which the glucocorticoid receptor (GR) affects actin assembly and stabilization ENSG00000070831 ENSG00000163914 PMC2128044__F12 Hierarchical representation of the JAK-STAT pathway with SOCS1 subsystem as a coordinator ENSG00000111537 ENSG00000115415 PMC2276871__F1 Steroid receptor expression in postnatal day 5–10 developing prostates from oil-treated control rats (A) and neonatally estrogenized rats (B) PMC3420817__F6 12-LIPOXYGENASE AND THE REGULATION OF HYPOXIA-INDUCIBLE FACTOR IN PROSTATE CANCER CELLS ENSG00000198793 PMC3509372__F1 Treg regulatory pathways ENSG00000163599 ENSG00000049768 PMC9110515__F1 White and brown adipose tissue functionality is impaired by fine particulate matter (PM2.5) exposure ENSG00000108691 ENSG00000169047 ENSG00000136869 PMC7565148__F7 Summary of WARS1 signaling pathway in macrophages ENSG00000081041 ENSG00000172936 ENSG00000136869 PMC6852217__F1 Genes encoding the enzymes involved in Vitamin D action and metabolic pathway ENSG00000111012 ENSG00000019186 ENSG00000186104 ENSG00000135929 PMC2722023__F4 Genome-Wide mRNA Expression Analysis of Hepatic Adaptation to High-Fat Diets Reveals Switch from an Inflammatory to Steatotic Transcriptional Program ENSG00000156735 ENSG00000110031 ENSG00000095321 ENSG00000138030 ENSG00000113161 ENSG00000099940 ENSG00000165527 ENSG00000100033 ENSG00000229314 ENSG00000145431 ENSG00000134321 ENSG00000009950 ENSG00000109084 ENSG00000197594 ENSG00000263528 ENSG00000103365 ENSG00000140859 ENSG00000112299 ENSG00000131473 ENSG00000009724 ENSG00000178078 ENSG00000269335 ENSG00000116741 ENSG00000166278 ENSG00000132170 ENSG00000070367 ENSG00000006451 ENSG00000187288 ENSG00000161533 ENSG00000280477 ENSG00000183020 ENSG00000188611 ENSG00000172936 ENSG00000123689 ENSG00000127863 ENSG00000114115 ENSG00000198911 ENSG00000166557 ENSG00000128965 PMC7801281__F3 ROS production mediated by diverse signaling pathways ENSG00000167107 ENSG00000167468 ENSG00000111684 ENSG00000062485 PMC5729474__F4 The highlighted metabolic alterations in leiomyomas of the FH and MED12 subtypes ENSG00000184634 PMC10474176__F6 NEDD8-activating enzyme E1 UBA3 orchestrates the immunosuppressive microenvironment in lung adenocarcinoma via the NF-кB pathway ENSG00000108691 ENSG00000144744 ENSG00000125538 ENSG00000164400 PMC2643067__F1 De novo purine biosynthesis pathway PMC5694536__F7 Schematic diagram depicting the role of Hoxa2 in proliferation and osteogenic differentiation of the palatal mesenchyme ENSG00000110711 ENSG00000291837 ENSG00000105996 PMC3082324__F7 Serpinin formation, its signaling pathway, and PN-1-dependent biogenesis of secretory granules in (neuro)endocrine cells ENSG00000185591 PMC5364965__F2 Notch gene signaling pathway interactions ENSG00000004975 ENSG00000148400 ENSG00000179111 ENSG00000133961 ENSG00000184916 ENSG00000114315 ENSG00000106003 PMC8689194__F3 Endotoxin causes inflammation and leaky gut through activation of NFKB pathways ENSG00000170458 ENSG00000172936 ENSG00000175104 PMC6620596__F2 STAT3 signaling pathway and inhibition approaches ENSG00000091704 ENSG00000291971 ENSG00000138798 ENSG00000168610 ENSG00000146648 PMC7796296__F9 Involvement of the ERK/HIF-1A/EMT Pathway in XCL1-Induced Migration of MDA-MB-231 and SK-BR-3 Breast Cancer Cells ENSG00000170558 ENSG00000168036 ENSG00000173578 ENSG00000143184 PMC4195781__F1 Location, location, and location: compartmentalization of Hedgehog signaling at primary cilia ENSG00000166813 PMC3652284__F1 Regulation of Wnt/Beta-catenin Signaling within and from Osteocytes ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000167941 ENSG00000104332 PMC3252978__F7 Summary of the results presented in this study ENSG00000131477 PMC3314865__F3 Targeting Mutant BRAF in Melanoma: Current Status and Future Development of Combination Therapy Strategies ENSG00000157764 ENSG00000198793 ENSG00000115825 ENSG00000139687 PMC3024228__F1 General pathway for phosphatidylinositide (PI) synthesis ENSG00000124102 ENSG00000115020 PMC7017348__F5 Multi-component feedback loops and multi-component signaling networks involving SNAIL and non-coding RNAs ENSG00000198740 ENSG00000168036 ENSG00000133961 ENSG00000196628 ENSG00000140443 PMC4461463__F1 Scheme for arginase catabolism of L-arginine to L-ornithine/urea or L-citrulline/NO, production of polyamines and anabolism and catabolism of proline ENSG00000036473 PMC6232116__F2 Communality network analysis for k-clique 9 ENSG00000087245 ENSG00000284238 ENSG00000005339 ENSG00000070831 ENSG00000065361 ENSG00000291971 ENSG00000138798 ENSG00000170558 ENSG00000173039 ENSG00000171791 ENSG00000149311 ENSG00000175054 ENSG00000101773 ENSG00000169750 ENSG00000135446 ENSG00000104320 ENSG00000197299 ENSG00000123374 ENSG00000100985 ENSG00000146648 ENSG00000114166 PMC6232116__F4 Significant correlation of degree centrality between the OncoPPi BC network and our BC integrated network (p < 0.05), (r2 = 0.23688) ENSG00000019991 ENSG00000070831 ENSG00000291971 ENSG00000169047 ENSG00000198793 ENSG00000115904 ENSG00000168036 ENSG00000108443 ENSG00000091409 ENSG00000167965 ENSG00000121879 ENSG00000136997 ENSG00000150907 ENSG00000105810 ENSG00000104365 ENSG00000147168 ENSG00000065361 ENSG00000109320 ENSG00000173039 ENSG00000213341 ENSG00000168610 ENSG00000160691 ENSG00000110395 ENSG00000135446 ENSG00000010810 ENSG00000177606 ENSG00000146648 PMC7582904__F2 Mechanisms for restoring HLA class I expression ENSG00000157764 ENSG00000115415 ENSG00000138798 ENSG00000146648 PMC5642705__F5 Macrophage response to cpsA deletion ENSG00000171855 ENSG00000102962 ENSG00000115008 ENSG00000138346 ENSG00000081041 ENSG00000102871 ENSG00000163739 ENSG00000183486 ENSG00000157601 ENSG00000115267 ENSG00000185745 ENSG00000168040 ENSG00000277943 ENSG00000065833 ENSG00000108691 ENSG00000137965 ENSG00000108688 ENSG00000163734 PMC7490531__F7 Illustration of the IRE1-RIDD-miRNA Pathway in Luminal Breast Cancer Malignancy ENSG00000169213 ENSG00000100219 PMC3180262__F8 Hypothetical molecular signaling pathways of the expression of p27 by which moderate increase in the concentration of D-(+)-glucose down-regulates and deficiency of D-(+)-glucose or L-leucine up-regulates the expression of p27 ENSG00000284161 ENSG00000142082 PMC4020998__F1 Apigenin Modulates Insulin-like Growth Factor Axis: Implications for Prevention and Therapy of Prostate Cancer ENSG00000169291 ENSG00000169047 PMC6082930__F3 Smurf2 as an oncogene ENSG00000168036 ENSG00000146648 PMC9348941__SF2 Rutin and Quercetin Counter Doxorubicin-Induced Liver Toxicity in Wistar Rats via Their Modulatory Effects on Inflammation, Oxidative Stress, Apoptosis, and Nrf2 ENSG00000079999 ENSG00000167419 PMC4748851__F2 Neurofibromatosis type 2 ENSG00000070831 ENSG00000184110 ENSG00000163914 ENSG00000026508 ENSG00000146648 PMC8005619__F2 DNA Sensing pathways by herpesvirus ENSG00000150782 ENSG00000164430 ENSG00000163568 PMC8005619__F1 Intracellular sensing of herpesvirus DNA by DNA sensors and activation of signaling pathway ENSG00000150782 ENSG00000239732 ENSG00000164430 ENSG00000163568 ENSG00000125538 ENSG00000163565 ENSG00000172936 ENSG00000276561 PMC9393484__F1 Motor, epileptic, and developmental phenotypes in genetic disorders affecting G protein coupled receptors-cAMP signaling ENSG00000184845 ENSG00000121905 ENSG00000149295 PMC6754303__F2 Pathogenesis and Clinical Features of the Acute Hepatic Porphyrias (AHPs) ENSG00000066926 ENSG00000256269 PMC4176998__F9 Schematic diagram demonstrating speculated roles of ER stress signaling pathways in diabetic cardiomyopathy. Firstly, under pathological condition of hyperglycemia in myocytes, ROS is generated by glucose oxidation in mitochondria ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC5930467__F6 Verteporfin in bladder cancer cell ENSG00000150457 ENSG00000131023 PMC3668775__F9 Proposed model for the attenuated response to type I IFNs in human pluripotent cells ENSG00000213928 ENSG00000187608 ENSG00000105397 PMC2943859__F5 Death receptor signaling and its interdigitation with the mitochondrial pathway of apoptosis ENSG00000168040 PMC9600385__F2 Melatonin and Indole-3-Acetic Acid Synergistically Regulate Plant Growth and Stress Resistance ENSG00000144712 ENSG00000069956 PMC6590351__F4 Potential therapeutic target proposed to block leukaemia properties induced by the presence of CBFA2T3‐GLIS2 ENSG00000129993 ENSG00000087586 PMC6977166__F2 Overview of the affected pathways in the THP-1 cells after treatment with the free MTX and MTX loaded NPs ENSG00000136877 ENSG00000137563 PMC10770036__F0 Novel dual inhibitors of PARP and HDAC induce intratumoral STING-mediated antitumor immunity in triple-negative breast cancer ENSG00000169245 ENSG00000183735 ENSG00000164430 ENSG00000273686 PMC9246955__F2 Riluzole regulates pancreatic cancer cell metabolism by suppressing the Wnt-Beta-catenin pathway ENSG00000142192 ENSG00000002330 ENSG00000111837 PMC9117704__F2 Salvia miltiorrhiza in Breast Cancer Treatment: A Review of Its Phytochemistry, Derivatives, Nanoparticles, and Potential Mechanisms ENSG00000132646 ENSG00000168610 PMC8503266__F1 Molecular Biomarkers of Vestibular Schwannoma Growth: Progress and Prospects ENSG00000070831 ENSG00000149269 ENSG00000026508 PMC4385926__F9 Simplified model depicting (a) Novel positive feedback loop between TGF-Beta-SMAD3 and KLF17 in cancer cells ENSG00000147649 ENSG00000182568 ENSG00000171872 ENSG00000113140 ENSG00000182985 PMC5278824__F1 Regulation of sGC via hsp90, Cellular Heme, sGC Agonists, and NO: New Pathways and Clinical Perspectives ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000188690 ENSG00000115657 PMC10955158__F5 FLRT3 and TGF‐B/SMAD4 signalling: Impacts on apoptosis, autophagy and ion channels in supraventricular tachycardia ENSG00000125848 ENSG00000156574 PMC9117704__F5 Salvia miltiorrhiza in Breast Cancer Treatment: A Review of Its Phytochemistry, Derivatives, Nanoparticles, and Potential Mechanisms ENSG00000168610 PMC3159046__F6 Binge cocaine administration in adolescent rats affects amygdalar gene expression patterns and alters anxiety-related behavior in adulthood ENSG00000154764 ENSG00000005339 ENSG00000100592 ENSG00000168036 ENSG00000150394 ENSG00000285485 ENSG00000155760 ENSG00000204217 ENSG00000118946 PMC8040227__F2 Canonical and non-canonical activation of NLRP3 ENSG00000162711 ENSG00000102871 ENSG00000175104 ENSG00000127191 ENSG00000184216 PMC2083698__F6 Promiscuous Mutations Activate the Non-Canonical NF-kB Pathway in Multiple Myeloma ENSG00000109320 ENSG00000111321 ENSG00000131323 ENSG00000083799 ENSG00000127191 PMC10648520__F8 Brief Review of Bone Cell Function and Importance ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC6028652__F7 Model of MAPK signaling pathway in MAP3K1; MAP2K4 wild-type or mutant cells ENSG00000120875 ENSG00000177606 ENSG00000095015 ENSG00000065559 PMC8603984__F6 cGAS/STING: novel perspectives of the classic pathway ENSG00000183735 ENSG00000164430 ENSG00000123240 ENSG00000156026 ENSG00000198793 ENSG00000158828 ENSG00000168404 PMC8503266__F3 Molecular Biomarkers of Vestibular Schwannoma Growth: Progress and Prospects ENSG00000104856 ENSG00000138798 PMC8503266__F2 Molecular Biomarkers of Vestibular Schwannoma Growth: Progress and Prospects ENSG00000114978 ENSG00000150457 ENSG00000073756 ENSG00000131023 PMC7980590__F6 Flow chart for the functions of miR-4429 and DLX1 in PCa cells ENSG00000154059 ENSG00000168036 PMC6258145__F6 Pictorial Abstract showing that the molecular or therapeutic inhibition of TRPM7 expression and/or activity attenuates the cancer stem cell-like and metastatic phenotypes of lung cancer cells through the modulation of the Hsp90A/uPA/MMP2 signaling ENSG00000087245 ENSG00000092439 ENSG00000170558 ENSG00000136826 PMC12056177__F10 Schematic description of kinase signaling pathways in Amyotrophic lateral sclerosis ENSG00000151502 ENSG00000177169 ENSG00000183735 ENSG00000123240 ENSG00000137601 ENSG00000137275 ENSG00000146216 ENSG00000168404 ENSG00000285379 ENSG00000147894 PMC3357548__F3 TWEAK signaling pathway: illustration of the TWEAK signaling pathway as visualized in NetSlim web page ENSG00000104856 ENSG00000108691 ENSG00000177606 ENSG00000173039 ENSG00000213341 ENSG00000168040 PMC3133775__F2 Second messengers and membrane trafficking direct and organize growth cone steering ENSG00000144935 ENSG00000137672 ENSG00000138741 ENSG00000075213 PMC8921770__F9 Lonafarnib Inhibits Farnesyltransferase via Suppressing ERK Signaling Pathway to Prevent Osteoclastogenesis in Titanium Particle-Induced Osteolysis ENSG00000164935 ENSG00000102575 ENSG00000100985 ENSG00000131196 ENSG00000143387 PMC8007973__F4 The Wnt pathway in normal tissue (A) and in our two pancreoblastoma cases (B) ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC8229878__F3 Human Granulosa Cells—Stemness Properties, Molecular Cross-Talk and Follicular Angiogenesis ENSG00000173992 ENSG00000169047 PMC3539134__F2 Inhibition of insulin signaling pathway by SOCS1 and SOCS3 ENSG00000169047 PMC8087698__F1 Serine synthesis pathway (SSP) and downstream anabolic pathways ENSG00000092621 ENSG00000135069 ENSG00000146733 PMC7505148__F5 CORM-A1 on glycolysis and pentose phosphate pathway (PPP) metabolites in platelets ENSG00000180210 PMC5143318__F7 In silico analysis of Noggin interactions with other proteins ENSG00000107779 ENSG00000285109 ENSG00000183072 ENSG00000183691 PMC8275408__F1 Mitochondria in Liver Ischemia-Reperfusion Injury: From Aspects of Mitochondrial Oxidative Stress, Mitochondrial Fission, Mitochondrial Membrane Permeable Transport Pore Formation, Mitophagy, and Mitochondria-Related Protective Measures ENSG00000189403 ENSG00000172936 PMC6591367__F7 Possible underlying mechanism of PAR4 signaling ENSG00000150907 ENSG00000198793 ENSG00000049768 PMC7219893__F1 (Color online) A schematic overview of the indices of mindfulness and anxiety demonstrating their inverse relationship ENSG00000132693 PMC9178270__F1 Immune Regulator Retinoic Acid-Inducible Gene I (RIG-I) in the Pathogenesis of Cardiovascular Disease ENSG00000183735 ENSG00000088888 PMC8947539__F1 Aging of the Immune System: Focus on Natural Killer Cells Phenotype and Functions ENSG00000293604 ENSG00000231179 ENSG00000180644 ENSG00000204520 PMC3763924__F1 Pathways of ICL repair ENSG00000188827 ENSG00000187790 ENSG00000276787 PMC11048425__F5 Proposed metabolic routes associated with lipid and Beta-carotene biosynthetic pathways in ΔcarRP WJ11 in comparison with the WJ11 strain ENSG00000124479 ENSG00000122966 PMC3805859__F1 Integration of microRNA and epigenetic regulation pathways ENSG00000139546 ENSG00000092847 ENSG00000123908 PMC8797156__F2 Research Progress on Leucine-Rich Alpha-2 Glycoprotein 1: A Review PMC6156139__F2 Smad-dependent and Smad-independent pathways of TGFB signaling associated with EndMT ENSG00000198742 PMC5922974__F6 Genes directly effecting TAG biosynthesis in R ENSG00000131473 ENSG00000143158 ENSG00000074800 ENSG00000124253 ENSG00000060762 ENSG00000026103 PMC4806601__F1 Genetic variants in the MicroRNA biosynthetic pathway Gemin3 and Gemin4 are associated with a risk of cancer: a meta-analysis ENSG00000092847 ENSG00000134698 ENSG00000123908 PMC9633197__F7 Molecular Mechanism of Epimedium Extract against Ischemic Stroke Based on Network Pharmacology and Experimental Validation ENSG00000128342 ENSG00000115718 PMC3583293__F7 Model depicting how Shh promotes CGNP proliferation through combined effects on Gli1/2 and the mTOR pathway components eIF4E and S6K ENSG00000169047 ENSG00000164690 ENSG00000128602 PMC4434964__F9 Models of EGF network and CNP/NPR2 signaling in the regulation of LH-induced ovulation ENSG00000138798 ENSG00000173786 ENSG00000159899 ENSG00000146648 PMC9687797__F3 Epigenetics in the Development and Progression of Multiple Myeloma ENSG00000128272 ENSG00000168610 PMC7141597__F1 Division of labor between type I and type III IFNs in antiviral response ENSG00000105397 ENSG00000147896 ENSG00000125347 ENSG00000142166 PMC3602699__F9 Summary of signaling pathway by which PP-fold peptides increase cell proliferation ENSG00000198793 ENSG00000131096 PMC4091682__F1 EGFR/PI3K Pathway ENSG00000134057 ENSG00000198793 ENSG00000168610 ENSG00000146648 PMC3399380__F2 IGF-IR signaling pathway ENSG00000169047 ENSG00000198793 PMC5401756__F5 Resistin signaling ENSG00000172936 ENSG00000136869 ENSG00000150455 PMC5401756__F4 Adiponectin signaling via AdipoR1 and AdipoR2 activation ENSG00000198793 ENSG00000285070 PMC12219892__F2 Scheme of the study design and workflow for transcriptomic and metabolomic analyses ENSG00000164949 PMC5401756__F6 Visfatin signaling ENSG00000077463 ENSG00000096717 ENSG00000168610 PMC2857646__F1 Schematic of the TGFB signaling pathway PMC4281710__F2 NOD2-interaction partners influence a wide range of NOD2 functions ENSG00000162711 ENSG00000167207 ENSG00000187796 ENSG00000140279 ENSG00000091592 ENSG00000132357 ENSG00000091106 ENSG00000076604 ENSG00000127837 ENSG00000088888 ENSG00000110446 ENSG00000112851 ENSG00000142405 ENSG00000084112 ENSG00000105483 ENSG00000084774 PMC4281710__F1 The domain architecture of NOD1, NOD2 and RIP2 ENSG00000167207 ENSG00000132357 ENSG00000106100 PMC8959940__F1 Microglia Polarization: A Novel Target of Exosome for Stroke Treatment ENSG00000138135 ENSG00000102908 ENSG00000148400 ENSG00000184216 PMC9255238__F1 An overview of resistance to Human epidermal growth factor receptor 2 (Her2) targeted therapies in breast cancer ENSG00000019991 ENSG00000135218 ENSG00000291971 ENSG00000198793 ENSG00000140443 ENSG00000026103 PMC6191506__F4 Hemoglobin production and redox homeostasis in erythrocytes ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000158578 ENSG00000188690 PMC4216012__F1 Wnt/Beta-Catenin Signaling Modulates Human Airway Sensitization Induced by B2-Adrenoceptor Stimulation ENSG00000281324 ENSG00000169071 ENSG00000162337 ENSG00000100592 ENSG00000134982 ENSG00000163914 ENSG00000165879 ENSG00000168036 PMC2784766__F3 Complex role of the PLAU-PLAUR pathway in the airways ENSG00000115008 ENSG00000011422 ENSG00000105329 ENSG00000125538 ENSG00000146648 ENSG00000122194 ENSG00000135919 PMC4036353__F8 How TAZ/YAP direct TGFBeta-induced tumorigenic events ENSG00000172260 PMC8470361__F1 Glycogen Synthase Kinase-3: A Focal Point for Advancing Pathogenic Inflammation in Depression ENSG00000136869 ENSG00000168610 PMC7976442__F5 Kyoto Encyclopedia of Genes and Genomes analysis of predicted pathways ENSG00000128052 ENSG00000126895 ENSG00000074410 PMC4983259__F1 O-GlcNAcylation in Cancer Biology: Linking Metabolism and Signaling ENSG00000131473 ENSG00000147162 ENSG00000198408 ENSG00000198793 ENSG00000169710 ENSG00000159399 PMC5401756__F2 Leptin signal transduction ENSG00000168610 PMC3634068__F6 Gene Expression Variability in Human Hepatic Drug Metabolizing Enzymes and Transporters ENSG00000131473 ENSG00000197408 ENSG00000019186 ENSG00000160870 ENSG00000023839 PMC5968197__F6 Dual-lock for G1-phase arrest in unfertilized mature starfish eggs ENSG00000172680 ENSG00000093009 PMC4176051__F2 Pathway analysis ENSG00000112280 ENSG00000130545 ENSG00000198380 ENSG00000143162 ENSG00000138119 ENSG00000165795 ENSG00000129173 ENSG00000143570 ENSG00000129007 PMC6506414__F14 N-Linked glycan (A) and the calnexin cycle (B) ENSG00000136731 ENSG00000134109 ENSG00000116406 ENSG00000088298 PMC5968197__F9 MPF-based meiotic cell cycle control: Half a century of lessons from starfish oocytes ENSG00000128989 ENSG00000143420 ENSG00000276876 PMC6952935__F1 Schematic representation of the metastatic cascade ENSG00000112715 ENSG00000174807 PMC5389954__F2 Synthetic diagram of opposing effects of PPAR gamma and canonical WNT/beta-catenin signaling in cancer ENSG00000136997 ENSG00000168036 PMC9657779__F10 Regulatory Role of Sphingosine-1-Phosphate and C16:0 Ceramide, in Immunogenic Cell Death of Colon Cancer Cells Induced by Bak/Bax-Activation ENSG00000127191 PMC5389954__F1 Schema of interactions between the canonical WNT/beta-catenin pathway and PPAR gamma under aerobic glycolysis conditions in cancer ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000136997 ENSG00000168036 ENSG00000198125 PMC3076924__F2 Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders ENSG00000198793 ENSG00000164305 PMC3076924__F4 Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders ENSG00000128272 ENSG00000144895 ENSG00000100219 ENSG00000127191 PMC7353017__F1 EGFR (epidermal growth factor receptor) and VEGFR (vascular endothelial growth factor receptor) signalization pathways ENSG00000157764 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC3433406__F5 Large scale phosphoproteome analysis of LNCaP human prostate cancer cells ENSG00000029363 ENSG00000181163 ENSG00000044115 ENSG00000103222 ENSG00000196591 ENSG00000168036 ENSG00000037474 ENSG00000035928 ENSG00000074201 ENSG00000231377 ENSG00000067369 ENSG00000166508 ENSG00000104177 ENSG00000284254 ENSG00000088247 ENSG00000129245 ENSG00000108256 ENSG00000145216 ENSG00000197081 ENSG00000198561 ENSG00000126777 ENSG00000100345 ENSG00000127022 ENSG00000086758 ENSG00000129347 ENSG00000065978 ENSG00000168066 ENSG00000273772 ENSG00000054118 ENSG00000047849 ENSG00000133422 ENSG00000111786 ENSG00000176102 ENSG00000138385 ENSG00000124783 PMC6327716__F6 The ubiquitylation of glycoprotein (GP) VI signalling pathway ENSG00000291971 ENSG00000010810 ENSG00000197943 ENSG00000010671 PMC2777484__F1 Folate-mediated 1-carbon metabolism ENSG00000284320 ENSG00000228716 PMC6095079__F3 Findings of network and pathway analysis ENSG00000111537 ENSG00000136842 ENSG00000167768 ENSG00000186716 ENSG00000158578 ENSG00000205809 ENSG00000150337 ENSG00000180644 ENSG00000115523 PMC8402498__F11 Escherichia coli Alpha-Hemolysin HlyA Induces Host Cell Polarity Changes, Epithelial Barrier Dysfunction and Cell Detachment in Human Colon Carcinoma Caco-2 Cell Model via PTEN-Dependent Dysregulation of Cell Junctions ENSG00000147044 ENSG00000105664 ENSG00000130545 ENSG00000163914 PMC8402498__F10 Escherichia coli Alpha-Hemolysin HlyA Induces Host Cell Polarity Changes, Epithelial Barrier Dysfunction and Cell Detachment in Human Colon Carcinoma Caco-2 Cell Model via PTEN-Dependent Dysregulation of Cell Junctions ENSG00000002330 ENSG00000086015 PMC7092476__F6 Signaling pathway enrichment analysis of core targets of TWH for CD ENSG00000168040 PMC4550442__F3 Acetylation of IFNAR-ISGF3 pathway is required for the antiviral activity of IFNA ENSG00000213928 ENSG00000142166 PMC4085347__F4 A mechanism showing tyrosine kinase receptor induced regulation of Nrf2 nuclear–cytoplasmic shuttling under redox homeostasis conditions ENSG00000291971 PMC4085347__F3 Diagrammatic presentation of regulation of Keap1-Nrf2-ARE pathway ENSG00000090402 ENSG00000178573 ENSG00000177606 ENSG00000025800 PMC9271918__F2 Molecular Mechanisms of Plant Responses to Salt Stress ENSG00000110934 ENSG00000163788 PMC9271918__F1 Molecular Mechanisms of Plant Responses to Salt Stress ENSG00000110934 ENSG00000115904 ENSG00000100485 PMC8435612__F2 Long Non-coding RNAs in Pathogenesis of Neurodegenerative Diseases ENSG00000150782 ENSG00000142192 ENSG00000104290 PMC7054735__F1 Therapeutic approaches for osteogenesis imperfecta ENSG00000178860 ENSG00000162337 ENSG00000167941 ENSG00000168036 PMC4464465__F4 Balance of inflammatory pathways and interplay of immune cells in the liver during homeostasis and injury ENSG00000102871 ENSG00000168040 ENSG00000127191 PMC6298633__F13 Schematic illustrating the potential contributions of ADAM9 (a disintegrin and metalloproteinase domain-9) to various chronic obstructive pulmonary disease phenotypes ENSG00000168615 ENSG00000146648 PMC11857241__F2 Our manuscript denotes the neuroprotective effects of many phytochemical classes, including those from flavonoids and alkaloids, against neurodegeneration ENSG00000162711 ENSG00000096717 PMC7904598__F2 Bi-directional EV-mediated communication between astrocytes and glioblastoma cells ENSG00000131095 ENSG00000168610 PMC11857241__F1 During neurodegeneration, critical pro-inflammatory and oxidative molecular pathways are involved in the occurrence of neurodegenerative conditions ENSG00000162692 ENSG00000096717 PMC4412741__F2 Effect of Antibodies on Endothelium ENSG00000069482 ENSG00000291971 ENSG00000198793 ENSG00000163914 ENSG00000164327 PMC4412741__F1 Effect of Antibodies on Endothelium ENSG00000110799 ENSG00000291971 ENSG00000163914 PMC7785707__F7 Proposed molecular mechanisms ENSG00000278718 ENSG00000162711 ENSG00000179632 ENSG00000171791 PMC4204167__F2 The Kelch-like ECH-associated protein 1 (Keap1)-nuclear factor E2-related factor 2 (Nrf2)-antioxidant response elements (ARE) signaling pathway ENSG00000178573 ENSG00000079999 PMC10707854__F3 Mechanism and Progress of Natural Products in the Treatment of NAFLD-Related Fibrosis ENSG00000134982 ENSG00000168036 ENSG00000108821 PMC7589024__F10 Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation via HMGB1/TLR4/NF‐KB and TNF‐A/TNFR1/NF‐KB pathways ENSG00000125538 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000127191 PMC10707854__F2 Mechanism and Progress of Natural Products in the Treatment of NAFLD-Related Fibrosis PMC10242070__F5 Transcriptomic signatures reveal a shift towards an anti-inflammatory gene expression profile but also the induction of type I and type II interferon signaling networks through aryl hydrocarbon receptor activation in murine macrophages ENSG00000066294 ENSG00000140505 ENSG00000020633 ENSG00000103522 ENSG00000125347 ENSG00000140465 ENSG00000168610 ENSG00000276561 ENSG00000188676 ENSG00000106546 ENSG00000104870 ENSG00000138378 ENSG00000239732 ENSG00000166145 ENSG00000187554 PMC4734677__F6 Activation of Dll4/Notch Signaling and Hypoxia-Inducible Factor-1 Alpha Facilitates Lymphangiogenesis in Lacrimal Glands in Dry Eye ENSG00000128917 ENSG00000148400 ENSG00000150630 PMC5919962__F1 Platelet targeted therapeutics ENSG00000110799 ENSG00000291971 ENSG00000163914 ENSG00000171540 ENSG00000150459 ENSG00000122194 PMC5192336__F2 MUC induces inflammasome activation ENSG00000162711 ENSG00000265972 PMC7704135__F5 Neuroactive ligand-receptor interaction signaling pathway ENSG00000152266 ENSG00000030582 ENSG00000112964 ENSG00000146469 ENSG00000248329 ENSG00000157017 ENSG00000081051 ENSG00000075073 ENSG00000274473 ENSG00000169836 ENSG00000183395 ENSG00000175054 ENSG00000112977 ENSG00000139574 ENSG00000069482 ENSG00000004948 PMC9515687__F3 Inflammasome NLPR3 in the Development and Therapy of Periodontitis ENSG00000278718 ENSG00000162711 ENSG00000185515 ENSG00000125538 PMC5214768__F8 Interaction map representing CNV-altered genes enriched in GO classes and grouped on the basis of their main biological processes ENSG00000185818 ENSG00000204176 ENSG00000030582 ENSG00000276644 ENSG00000184185 ENSG00000099940 ENSG00000171791 ENSG00000155974 ENSG00000277641 ENSG00000179915 ENSG00000071564 ENSG00000040608 ENSG00000183527 ENSG00000186472 ENSG00000185838 PMC8761767__F1 Interleukin-33/ Suppression of Tumorigenicity 2 in Renal Fibrosis: Emerging Roles in Prognosis and Treatment ENSG00000108691 ENSG00000137033 ENSG00000172936 ENSG00000185187 ENSG00000175104 PMC8358430__F1 Inflammatory Cytokine Storms by Mesenchymal Stem Cells ENSG00000178860 ENSG00000168610 ENSG00000164305 PMC7495247__F1 A) Schematic showing how COVID-19 triggers hyper-activation of the immune-response, generating a cytokine storm ENSG00000166278 PMC7677509__F6 Cyclin G2 inhibiting the growth and metastasis of OSCC by binding to IGFBP3 and regulating the FAK-SRC-STAT signal pathway ENSG00000138764 ENSG00000291971 ENSG00000100985 ENSG00000168610 PMC3896626__F2 Interaction among differentially modulated genes in the apoptosis biochemical pathway, using KEGG, after hgf-FNDF-LC50 and SCFA-LC50 treatments ENSG00000149311 ENSG00000002330 ENSG00000102871 ENSG00000138794 ENSG00000164399 ENSG00000171791 ENSG00000168040 ENSG00000026103 PMC3896626__F1 Interaction among differentially modulated genes in the cell cycle biochemical pathway, using KEGG, after hgf-FNDF-LC50 and SCFA-LC50 treatments ENSG00000145604 ENSG00000094804 ENSG00000108055 ENSG00000132646 ENSG00000115942 ENSG00000135336 ENSG00000123374 ENSG00000164754 ENSG00000205250 ENSG00000277273 ENSG00000276876 ENSG00000093009 PMC10951222__F5 Tumor evolutionary analysis and clinical vignettes for patients who derived clinical benefit from palbociclib, everolimus, and exemestane triplet therapy ENSG00000055609 ENSG00000121879 ENSG00000196712 PMC9351107__F3 Targeting KRAS mutant cancers: from druggable therapy to drug resistance ENSG00000198793 ENSG00000115904 PMC4686785__F8 PPI human module ENSG00000135439 ENSG00000033122 ENSG00000123104 ENSG00000104450 ENSG00000137825 ENSG00000081026 ENSG00000119878 ENSG00000163914 ENSG00000277236 ENSG00000166501 ENSG00000152208 ENSG00000197943 ENSG00000198010 ENSG00000137672 ENSG00000135423 ENSG00000142192 ENSG00000187682 ENSG00000168758 ENSG00000149091 ENSG00000116741 ENSG00000161714 ENSG00000107282 ENSG00000144935 ENSG00000069018 ENSG00000185532 ENSG00000276429 ENSG00000154146 PMC4012889__F1 Intricate network of TLR signaling and miRNAs ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000128191 ENSG00000184216 ENSG00000113360 PMC8913022__F2 Statin Use in Patients With Chronic Liver Disease and Cirrhosis: Current Evidence and Future Directions ENSG00000070831 ENSG00000127528 PMC11506310__F2 Non-canonical TRAIL signaling pathway ENSG00000137275 ENSG00000291971 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000168610 ENSG00000285379 PMC8762167__F1 Comprehensive Review of the Therapeutic Value of Urine-Derived Stem Cells ENSG00000002330 ENSG00000181019 ENSG00000187908 PMC11506310__F1 TRAIL-induced pro-apoptotic signaling pathway ENSG00000120868 ENSG00000168040 PMC6859927__F1 Representation of normal BRAF pathway ENSG00000157764 ENSG00000127948 PMC2878746__F1 Ret gene structure and signaling ENSG00000291971 ENSG00000171119 ENSG00000117407 ENSG00000125650 PMC2633625__F2 Toll-like receptors in skin ENSG00000174125 ENSG00000239732 ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC6425986__F4 Proteomic Analysis of the Human Anterior Pituitary Gland ENSG00000125879 ENSG00000090402 PMC3913963__F5 Beta-adrenergic signaling modulates multiple cellular processes in tumor progression and metastasis ENSG00000002330 ENSG00000198793 ENSG00000168610 PMC2649725__F7 Model showing the activation of the JNK pathway upon challenge by UVB ENSG00000188486 ENSG00000067900 ENSG00000084774 PMC4530868__F4 MicroRNA and Transcription Factor Mediated Regulatory Network Analysis Reveals Critical Regulators and Regulatory Modules in Myocardial Infarction ENSG00000100234 ENSG00000087245 ENSG00000102871 ENSG00000082512 ENSG00000173039 ENSG00000185591 ENSG00000112715 ENSG00000127191 ENSG00000168610 PMC4594993__F6 General model for basigin promotes the membrane localization of CD98 and activation of B1-integrin ENSG00000103769 ENSG00000134709 ENSG00000165527 ENSG00000124209 PMC7865797__F1 Carbon-source preferences and use in cancer metabolism ENSG00000092621 ENSG00000173599 ENSG00000099194 PMC4167483__F2 Sonic Hedgehog Signaling in Basal Cell Nevus Syndrome ENSG00000281324 ENSG00000162337 ENSG00000138798 ENSG00000198793 ENSG00000128602 PMC4167483__F1 Sonic Hedgehog Signaling in Basal Cell Nevus Syndrome ENSG00000173040 ENSG00000164161 ENSG00000166813 ENSG00000203965 ENSG00000128602 PMC10835878__F10 Mechanosensitive channel of large conductance enhances the mechanical stretching-induced upregulation of glycolysis and oxidative metabolism in Schwann cells ENSG00000198793 ENSG00000159399 PMC3915736__F2 Uncoupling T-cell expansion from effector differentiation in cell-based immunotherapy ENSG00000139193 ENSG00000134982 ENSG00000198793 ENSG00000127528 PMC5342493__F5 Novel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma ENSG00000105329 PMC8396170__F2 RasV12; scrib−/− Tumors: A Cooperative Oncogenesis Model Fueled by Tumor/Host Interactions ENSG00000262406 ENSG00000291971 PMC4326575__F1 Structure and signaling from the cilium and relationship with the autophagic pathway ENSG00000177169 ENSG00000109083 ENSG00000198793 ENSG00000134853 ENSG00000128602 ENSG00000057663 PMC6534064__F1 Drugs targeting Wnt/beta-catenin signaling in Desmoid-Type Fibromatosis ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000176887 ENSG00000168036 ENSG00000148848 PMC1569532__F1 Different types of regulatory T cells ENSG00000078747 ENSG00000049768 PMC6534064__F2 A schematic presentation of the Hedgehog signaling pathway and the drugs that interfere with this pathway in DTF ENSG00000107338 ENSG00000164161 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 PMC8088752__F7 Integrated stress response-mediated activation of mammalian RNA-dependent mRNA amplification ENSG00000128272 ENSG00000162600 ENSG00000169136 ENSG00000081791 PMC4559166__F1 Time-series transcriptome analysis for adaptive evolution of E ENSG00000197713 ENSG00000073578 ENSG00000122966 ENSG00000153574 PMC7663714__F2 Interplay between different proangiogenic factors and their corresponding modulatory microRNAs ENSG00000087245 ENSG00000137673 ENSG00000100985 ENSG00000112715 ENSG00000168610 PMC8962276__F1 Uremic Toxin Lanthionine Induces Endothelial Cell Mineralization In Vitro ENSG00000154122 ENSG00000162551 PMC6959318__F7 Model illustrating possible functions of DGAT1 and DGAT2 in human skeletal muscle cells ENSG00000285482 ENSG00000062282 ENSG00000026103 PMC7140640__F4 Molecular pathways of the unfolded protein response (UPR ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC9438316__F1 Metabolic cross-talk within the bone marrow milieu: focus on multiple myeloma ENSG00000131473 ENSG00000135404 ENSG00000115419 ENSG00000026103 PMC2674807__F2 Common polymorphisms in the genes associated with Alzheimer’s Disease (AD) ENSG00000142192 ENSG00000113600 ENSG00000196549 ENSG00000175899 ENSG00000119912 ENSG00000164305 ENSG00000137642 PMC6055827__F4 Lipopolysaccharide (LPS)‐ and serum amyloid A (SAA)‐mediated cellular production of inflammatory cytokines ENSG00000174125 ENSG00000183735 ENSG00000187554 ENSG00000172005 ENSG00000134070 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC9438316__F2 Metabolic cross-talk within the bone marrow milieu: focus on multiple myeloma ENSG00000117650 ENSG00000092621 ENSG00000165283 PMC4783980__F2 Inhibition of Calcium-induced T Lymphocyte Apoptosis pathway ENSG00000291761 ENSG00000124181 ENSG00000099991 PMC2654747__F2 Summary of enzyme-catalyzed thyronamine deiodinase reactions PMC9711860__F7 Illustration of how loss of cell–cell adhesion triggers cell migration ENSG00000156299 ENSG00000291971 ENSG00000168610 PMC8694526__F2 Recent Advances in Osteoclast Biological Behavior ENSG00000095585 ENSG00000170909 ENSG00000135605 ENSG00000010671 PMC3946634__F1 Tumor suppressive signatures of miR-200 ENSG00000169554 ENSG00000184384 ENSG00000285109 ENSG00000196782 ENSG00000105810 ENSG00000178691 PMC9198352__F2 Strategies of LncRNA DLX6-AS1 on Study and Therapeutics ENSG00000104814 ENSG00000006377 ENSG00000198793 PMC4220515__F1 Excess glucose and fatty-acid exposure linked to reduction of AMPK and consequent inflammation and fibrosis ENSG00000157500 ENSG00000159346 PMC4590251__F1 PirB-mediated growth cone collapse and axon growth inhibition.A classical axon inhibition signaling pathway: Nogo on the oligodendrocyte surface binds to the NgR-LINGO1-P75 receptor complex on the neuronal membrane ENSG00000163914 ENSG00000169783 PMC7564842__F1 Receptors and signaling pathways that activate the NFKB cascade ENSG00000172936 ENSG00000175104 ENSG00000127191 PMC5589138__F2 Normal and abnormal adrenal steroidogenesis in the zona fasciculata PMC3442804__F2 Phosphorylation is the switch that turns PEA-15 from tumor suppressor to tumor promoter ENSG00000138798 ENSG00000168040 PMC11989151__F9 Canonical MC1R signaling pathway ENSG00000291971 PMC4186703__F9 Non-Classical Renin-Angiotensin System and Renal Function ENSG00000130234 PMC8906937__F6 Solasonine Induces Apoptosis and Inhibits Proliferation of Bladder Cancer Cells by Suppressing NRP1 Expression ENSG00000138798 ENSG00000198793 ENSG00000112715 ENSG00000146648 PMC8195803__F3 Revisiting the role of mitochondria in spinal muscular atrophy ENSG00000048707 ENSG00000116688 ENSG00000247077 PMC6323673__F7 Bacterial and viral pathogen-associated molecular patterns induce divergent early transcriptomic landscapes in a bovine macrophage cell line ENSG00000172508 ENSG00000125826 ENSG00000128016 ENSG00000127129 PMC9405302__F5 Ozone Pollution, Oxidative Stress, Regulatory T Cells and Antioxidants ENSG00000065833 ENSG00000134982 ENSG00000163599 ENSG00000079999 PMC2819585__F7 MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis ENSG00000198901 PMC8280619__F1 Unraveling the role of liver sinusoidal endothelial cells in COVID-19 liver injury ENSG00000081041 ENSG00000110799 ENSG00000163739 PMC7791639__F7 Bleomycin induces fibrotic transformation of bone marrow stromal cells to treat height loss of intervertebral disc through the TGFBR1/Smad2/3 pathway ENSG00000178860 ENSG00000154736 ENSG00000149968 ENSG00000291748 ENSG00000108821 PMC7767860__F2 Canonical and non-canonical pathways of TGFB signaling ENSG00000170365 ENSG00000137834 ENSG00000157933 ENSG00000198793 PMC3427792__F1 Akt isoforms and glucose homeostasis - the leptin connection ENSG00000149212 PMC4569842__F1 Modular pathway rewiring of Saccharomyces cerevisiae enables high-level production of L-ornithine ENSG00000081181 ENSG00000122966 ENSG00000100412 PMC11649616__F3 Cancer-associated fibroblasts crosstalk with extracellular matrix ENSG00000138757 ENSG00000136997 ENSG00000150457 ENSG00000131023 PMC6770863__F1 TLR4–p38B MAPK–C/EBPB signaling pathway mediates the coordinate activation of UPP and ALP in cancer-induced muscle catabolism ENSG00000177169 ENSG00000172936 ENSG00000136869 ENSG00000150455 ENSG00000175104 ENSG00000139112 PMC8836041__F2 Autophagy by the Glycogen Synthase Kinase-3 (GSK-3) Signaling Pathway ENSG00000112561 PMC5330258__F1 VD3 is metabolized to 25(OH)D3 and 1,25(OH)2D3 by the classical pathway or to 20S(OH)D3 and 20S,23(OH)2D3 by CYP11A1 ENSG00000111012 ENSG00000186104 ENSG00000135929 PMC3954635__F4 Beta-catenin pathway ENSG00000197043 ENSG00000132911 ENSG00000134982 ENSG00000187741 ENSG00000168036 ENSG00000103241 ENSG00000171791 ENSG00000156475 ENSG00000053747 ENSG00000273772 ENSG00000173599 ENSG00000187908 ENSG00000115353 ENSG00000158545 ENSG00000169567 PMC9332053__F2 MTOR Signaling Pathway in Multiple Sclerosis; from Animal Models to Human Data ENSG00000162711 ENSG00000172680 ENSG00000134982 ENSG00000186716 ENSG00000198793 PMC9332053__F1 MTOR Signaling Pathway in Multiple Sclerosis; from Animal Models to Human Data ENSG00000125538 ENSG00000198793 ENSG00000118515 ENSG00000155792 ENSG00000164327 ENSG00000167965 ENSG00000101425 PMC6143528__F8 Action of OR2AT4 activation by Sandalore® and (unknown) endogenous ligand(s) in human hair follicle epithelium ENSG00000002330 ENSG00000113070 ENSG00000141753 ENSG00000171791 ENSG00000146648 ENSG00000140443 PMC3718392__F2 Targeting of PI3K/mTORC1 signaling in hamartoma syndromes ENSG00000062485 PMC3718392__F1 mTORC1 signaling ENSG00000169047 PMC8899613__F8 Plasma Proteome Profiling of Patients With In-stent Restenosis by Tandem Mass Tag-Based Quantitative Proteomics Approach ENSG00000189058 ENSG00000172680 ENSG00000100979 PMC11204099__F8 Chlorogenic acid and cinnamaldehyde synergism on Akt-mediated signaling pathway downstream target proteins ENSG00000170558 ENSG00000100985 PMC3844273__F6 Hypothetical estrogen signaling pathways in human cerebral vascular endothelial cells ENSG00000113070 ENSG00000146648 PMC6771382__F2 Summary of HR processes and HR proteins reported for sumoylation and interacting with SUMO ENSG00000138083 ENSG00000188827 ENSG00000051180 ENSG00000178966 ENSG00000126778 ENSG00000100625 PMC6888459__F3 Intracellular trafficking of EAAT3 ENSG00000133961 ENSG00000184985 PMC6122073__F4 Single-strand break signaling ENSG00000188486 ENSG00000149311 ENSG00000175054 ENSG00000164053 ENSG00000132646 ENSG00000138385 PMC3718996__F8 Graphs showing the different regulation of glioma cell signaling when cells were cultured on biomatrix, myelin and unmyelinated tissue (retina) ENSG00000106683 ENSG00000182541 PMC8342223__F3 Complex role of AIM2 in autoimmune diseases and cancers ENSG00000163568 ENSG00000116688 ENSG00000125538 ENSG00000198793 PMC7649293__F5 An Msx2-Sp6-Follistatin Pathway Operates During Late Stages of Tooth Development to Control Amelogenesis ENSG00000120149 ENSG00000134363 PMC5598536__F2 Canonical pathway illustrations of CBA classifier ENSG00000178573 PMC4977872__F9 Hypothesis of “The regulation of H3K27me3 on S ENSG00000169245 ENSG00000111537 ENSG00000273686 PMC11641149__F1 Regulatory factors of mitochondrial dynamics, associated with Alzheimer’s disease (AD) and Parkinson’s disease (PD) ENSG00000168958 ENSG00000116688 ENSG00000158828 ENSG00000171109 PMC5331536__F8 LSS improves cognitive function and prevents neuronal injury of AD rats via inhibiting the neuronal apoptosis signaling pathway ENSG00000002330 PMC6916339__F2 SHIP2 regulates the insulin signalling pathway ENSG00000124102 ENSG00000198087 PMC3262611__F1 Folic acid metabolism ENSG00000228716 PMC3377643__F2 TGFB and Iron Differently Alter HBV Replication in Human Hepatocytes through TGFB/BMP Signaling and Cellular MicroRNA Expression ENSG00000037965 ENSG00000157933 ENSG00000133937 ENSG00000115297 ENSG00000156574 ENSG00000020633 ENSG00000164093 ENSG00000175104 PMC8199207__F2 Immune Escape and Resistance to Checkpoint Inhibitor Therapies in Mismatch Repair Deficient Metastatic Colorectal Cancers ENSG00000164430 PMC8199207__F1 Immune Escape and Resistance to Checkpoint Inhibitor Therapies in Mismatch Repair Deficient Metastatic Colorectal Cancers ENSG00000168036 PMC6550542__F2 Interplay between enteroviruses and the host autophagy pathway ENSG00000188554 ENSG00000136436 ENSG00000099940 PMC7299703__F8 Apoptotic signalling pathway ENSG00000142192 ENSG00000002330 ENSG00000078098 ENSG00000084774 PMC7747089__F1 Induction of type I IFNs and ISGs by influenza virus ENSG00000088888 ENSG00000167207 ENSG00000138135 ENSG00000105397 ENSG00000115415 ENSG00000135114 ENSG00000172936 ENSG00000125347 ENSG00000276561 PMC6198670__F5 ARG1-arginine-immune suppression-fatigue pathway ENSG00000139193 ENSG00000113520 ENSG00000126353 ENSG00000118520 PMC10528430__F1 Microglial responses in Alzheimer’s Disease ENSG00000182578 ENSG00000168329 ENSG00000140678 ENSG00000137033 ENSG00000198793 ENSG00000077984 ENSG00000203710 ENSG00000183160 ENSG00000168610 ENSG00000019582 ENSG00000139180 ENSG00000115415 ENSG00000181631 ENSG00000136869 PMC8107375__F5 Fluticasone Propionate Suppresses Poly(I:C)-Induced ACE2 in Primary Human Nasal Epithelial Cells ENSG00000169245 ENSG00000130234 ENSG00000184012 ENSG00000164342 PMC3845396__F1 Regulation of AKT signalling activation ENSG00000132906 ENSG00000002330 ENSG00000198793 PMC6937972__F6 Strong association of calcium channel activity in NRXN1A+/− iPSC-derived neurons ENSG00000164220 ENSG00000152661 ENSG00000107562 ENSG00000166862 ENSG00000100346 ENSG00000171388 ENSG00000197461 ENSG00000183395 ENSG00000184500 ENSG00000074211 ENSG00000164742 ENSG00000102879 ENSG00000041982 ENSG00000134853 ENSG00000196639 ENSG00000138741 ENSG00000006116 ENSG00000126458 ENSG00000114279 PMC7934421__F1 Molecular pathomechanism of CRP-mediated damage in ischemic or hypoxemic tissue ENSG00000173599 ENSG00000244731 ENSG00000166278 ENSG00000132693 ENSG00000236625 PMC4863537__F1 Pharmacology and rationale for imatinib in the treatment of scleroderma ENSG00000291971 PMC4591505__F1 TCR-mediated integrin activation inside-out signaling ENSG00000213658 ENSG00000124181 PMC9035407__F10 RGS14 regulates PTH- and FGF23-sensitive NPT2A-mediated renal phosphate uptake via binding to the NHERF1 scaffolding protein ENSG00000118972 ENSG00000152266 ENSG00000169220 ENSG00000118515 ENSG00000109062 PMC5879088__F1 Canonical leptin signaling in hypothalamic neurons ENSG00000086991 ENSG00000115138 ENSG00000168610 PMC3287363__F7 Working model of ID/anemia-suppressed hippocampal IGF signaling ENSG00000150907 ENSG00000169047 ENSG00000198793 ENSG00000140443 PMC4166762__F1 Glucagon-like peptide 2 receptor (Glp2r)-induced intracellular signaling in hypothalamic proopiomelanocortin (POMC) neurons ENSG00000171105 ENSG00000115138 PMC7797159__F6 Cis- and trans-networks of DEGs and DE-lncRNAs of muscle development-related GO terms and signaling pathways ENSG00000162552 ENSG00000087095 ENSG00000160551 ENSG00000135090 ENSG00000291431 ENSG00000292354 ENSG00000115904 ENSG00000099942 ENSG00000081189 PMC5791065__F1 Activation of the B cell receptor signaling canonical pathway in FCRx versus SIS: a schematic representation ENSG00000071564 ENSG00000177455 ENSG00000095585 ENSG00000002330 ENSG00000070831 ENSG00000077420 ENSG00000150907 ENSG00000198793 ENSG00000196092 ENSG00000132478 ENSG00000010671 PMC8456902__F2 Estrogens in polycystic liver disease: A target for future therapies? ENSG00000164040 ENSG00000291971 ENSG00000146648 PMC8716792__F3 Ferroptosis Signaling and Regulators in Atherosclerosis ENSG00000139514 ENSG00000135423 ENSG00000086991 ENSG00000150457 ENSG00000131023 PMC8716792__F2 Ferroptosis Signaling and Regulators in Atherosclerosis ENSG00000178573 ENSG00000167468 PMC5669621__F1 Development of POMC neurons ENSG00000134438 ENSG00000242689 ENSG00000138083 ENSG00000115138 ENSG00000136352 ENSG00000164690 ENSG00000114315 ENSG00000168610 PMC9361782__F7 Dysregulated retinoic acid signaling in airway smooth muscle cells in asthma ENSG00000132906 ENSG00000135437 ENSG00000184254 ENSG00000152661 ENSG00000284807 ENSG00000114113 ENSG00000121039 ENSG00000128918 ENSG00000162496 ENSG00000118514 ENSG00000159388 ENSG00000112715 ENSG00000138207 ENSG00000003137 ENSG00000143320 ENSG00000114115 ENSG00000162444 ENSG00000073737 PMC8002083__F8 Illustrated model for our proposed molecular mechanism of how moscatilin inhibits HCC cell metastasis through inhibiting uPA expression via down-regulating Akt/NFKB signaling pathway ENSG00000004961 ENSG00000122194 PMC6274847__F2 Proline, ornithine, and arginine metabolism and transport in plants ENSG00000250799 ENSG00000122966 ENSG00000036473 PMC6299256__F3 IL-27 induction by C ENSG00000167207 ENSG00000115415 ENSG00000172936 ENSG00000142166 PMC6999710__F1 Mitophagy and Innate Immunity in Infection ENSG00000118369 ENSG00000215021 ENSG00000183735 ENSG00000188554 ENSG00000123240 ENSG00000116688 ENSG00000158828 ENSG00000069509 ENSG00000135093 PMC3808116__F2 Schematic overview of multiple feedback loops in the PI3K pathway ENSG00000169047 PMC10526229__F1 Notch Signaling by Small-Molecular Compounds and Its Potential in Anticancer Studies ENSG00000140564 ENSG00000090402 ENSG00000128917 ENSG00000074181 ENSG00000198793 ENSG00000090932 PMC8589993__F5 Systems pharmacology to reveal multi-scale mechanisms of traditional Chinese medicine for gastric cancer ENSG00000143799 ENSG00000138798 ENSG00000171791 ENSG00000150455 ENSG00000164305 ENSG00000150782 ENSG00000157227 ENSG00000149968 ENSG00000149269 ENSG00000056558 ENSG00000164400 ENSG00000136869 ENSG00000157625 ENSG00000174125 ENSG00000242689 ENSG00000100906 ENSG00000113070 ENSG00000173039 ENSG00000007908 ENSG00000168040 ENSG00000127191 ENSG00000073756 ENSG00000170458 ENSG00000177606 ENSG00000164136 ENSG00000184371 ENSG00000172936 ENSG00000131323 ENSG00000100985 ENSG00000175104 ENSG00000162692 ENSG00000146648 PMC9019162__F3 Genome-Wide Association Study for Tolerance to Paratuberculosis Identifies Candidate Genes Involved in DNA Packaging, DNA Damage Repair, Innate Immunity, and Pathogen Persistence ENSG00000012061 ENSG00000178257 ENSG00000146592 ENSG00000082512 ENSG00000213341 PMC11241191__F7 Schematic illustration of SRI regulating apoptosis in HCC ENSG00000075142 ENSG00000171791 ENSG00000168610 PMC6909887__F1 Mechanistic Target Of Rapamycin Complex 1 (mTORC1) signaling pathway with areas of potential pharmaceutical inhibition highlighted ENSG00000177058 ENSG00000239282 PMC2631022__F1 ECM-receptor interaction pathway enriched by human switch-like genes ENSG00000136457 ENSG00000135218 ENSG00000110799 ENSG00000026508 PMC8120246__F6 Dissecting the Roles of LncRNAs in the Development of Periventricular White Matter Damage ENSG00000171855 ENSG00000213928 ENSG00000170909 ENSG00000033327 ENSG00000105329 ENSG00000101307 ENSG00000150337 ENSG00000102575 ENSG00000010671 ENSG00000095585 ENSG00000077150 ENSG00000197943 ENSG00000115594 ENSG00000182578 ENSG00000104365 ENSG00000115008 ENSG00000259207 ENSG00000100906 ENSG00000269335 ENSG00000213341 ENSG00000127191 ENSG00000132170 ENSG00000143387 ENSG00000117020 ENSG00000111537 ENSG00000115415 ENSG00000004948 ENSG00000010810 ENSG00000184371 ENSG00000083799 ENSG00000100365 ENSG00000131196 PMC6491894__F1 Deletion of both cytosolic superoxide dismutases impacts metabolite concentrations and enzyme abundance of TCA cycle (A), glycolysis (B), and pentose phosphate pathway (C) ENSG00000143252 ENSG00000197713 ENSG00000073578 ENSG00000122966 ENSG00000117118 ENSG00000172005 ENSG00000153574 PMC5869054__F5 ABeta-driven Wnt-PCP pathway activation ENSG00000281324 ENSG00000100592 ENSG00000168036 ENSG00000166886 ENSG00000105723 ENSG00000155090 PMC4752324__F8 Key Role of ROS in the Process of 15-Lipoxygenase/15-Hydroxyeicosatetraenoiccid-Induced Pulmonary Vascular Remodeling in Hypoxia Pulmonary Hypertension ENSG00000132646 ENSG00000086991 ENSG00000171759 PMC12176845__F5 CircRNA: the potential biomarkers and therapeutic targets in oral squamous cell carcinoma (OSCC) ENSG00000128342 ENSG00000168610 PMC12176845__F4 CircRNA: the potential biomarkers and therapeutic targets in oral squamous cell carcinoma (OSCC) ENSG00000198793 ENSG00000112715 PMC12176845__F3 CircRNA: the potential biomarkers and therapeutic targets in oral squamous cell carcinoma (OSCC) ENSG00000175104 ENSG00000119681 PMC5300981__F3 TGFBeta-Smad signaling pathway in HSC PMC11727080__F1 Fate of glucose and fatty acids in macrophages and HCC cells ENSG00000157184 ENSG00000131473 ENSG00000079432 ENSG00000159399 ENSG00000062485 ENSG00000026103 PMC11727080__F2 Crossroad in amino acid metabolism in macrophages and HCC cells ENSG00000003989 ENSG00000115942 ENSG00000145321 ENSG00000118520 ENSG00000159399 PMC3628764__F1 Alternate routes of endocytic traffic of activated tyrosine kinase coupled cell surface receptors and the role of Cbl-family protein dependent ubiquitination ENSG00000110395 ENSG00000138798 ENSG00000146648 PMC9456329__F8 Synthetic Secoisolariciresinol Diglucoside (LGM2605) Prevents Asbestos-Induced Inflammation and Genotoxic Cell Damage in Human Mesothelial Cells ENSG00000162711 ENSG00000178573 ENSG00000189403 PMC4032345__F3 Comparative Proteomic Analyses Provide New Insights into Low Phosphorus Stress Responses in Maize Leaves ENSG00000159224 PMC8998804__F1 Transcription Factors with Targeting Potential in Gliomas ENSG00000128602 ENSG00000168610 ENSG00000146648 ENSG00000127948 PMC7379485__F7 ALDHHIGH cells regulatory mechanisms in cervical cancer cells ENSG00000281324 ENSG00000168036 PMC11739089__F6 Research progress on the synthesis process, detection method, pharmacological effects and application of glycocholic acid ENSG00000226275 PMC5848464__F1 Regulation of canonical and noncanonical pathways of NFKB activation by cylindromatosis (CYLD) ENSG00000104856 ENSG00000173039 ENSG00000111321 ENSG00000131323 ENSG00000083799 ENSG00000127191 PMC3941170__F2 Cell cycle regulation by p16Ink4b/p14ARF ENSG00000135446 ENSG00000105810 PMC11897346__F7 Graph model for the role of SR-A3 in protecting against MAFLD through the XIAP/PTEN/AKT axis ENSG00000198793 PMC8843879__F3 Critical roles of the lncRNA CASC11 in tumor progression and cancer metastasis: The biomarker and therapeutic target potential PMC5641214__F2 Leptomeningeal disease: current diagnostic and therapeutic strategies ENSG00000228716 ENSG00000136877 ENSG00000291814 ENSG00000137563 PMC8997752__F5 Beyond PD-L1—Identification of Further Potential Therapeutic Targets in Oral Cancer PMC6424911__F4 Changes in transcripts related to phenylpropanoid metabolism in response to aphid feeding in susceptible plants ENSG00000150787 ENSG00000084774 PMC6186589__F1 Schema of sortilin regulating EGFR trafficking () ENSG00000198793 ENSG00000163914 ENSG00000185483 ENSG00000146648 ENSG00000111737 PMC6800172__F1 Chemical structures (Panel A) of decursin (D), decursinol angelate (DA) and decursinol (DOH), and likely metabolic pathway (Panel B) of D and DA based on rodent data and human studies in vitro and in vivo ENSG00000172831 ENSG00000165841 PMC9163565__F3 New Progress in Basic Research of Macrophages in the Pathogenesis and Treatment of Low Back Pain ENSG00000168329 ENSG00000125538 ENSG00000136869 ENSG00000184344 ENSG00000121807 PMC4487054__F1 Signaling of SGK3 and AKT ENSG00000176692 ENSG00000002330 ENSG00000284571 ENSG00000185591 ENSG00000125968 ENSG00000121966 PMC5346358__F7 Mechanism of action of BNP inhibitory effect on LPS/ATP-induced IL-1B secretion in human THP-1 monocyte ENSG00000125538 PMC8213587__F3 Rethinking the biology of metastatic melanoma: a holistic approach ENSG00000157764 ENSG00000198793 ENSG00000136997 ENSG00000196712 PMC7706714__F3 Stresses in the metastatic cascade: molecular mechanisms and therapeutic opportunities ENSG00000157227 ENSG00000170558 ENSG00000100985 ENSG00000168610 PMC4150779__F7 Functional relevance of rapid transcriptional silencing in activated DCs ENSG00000162711 ENSG00000226275 ENSG00000187796 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC8698202__F2 Feline Coronavirus and Alpha-Herpesvirus Infections: Innate Immune Response and Immune Escape Mechanisms ENSG00000105397 ENSG00000144895 ENSG00000115415 ENSG00000135828 PMC6530577__F3 Endoplasmic Reticulum Stress in Metabolic Liver Diseases and Hepatic Fibrosis ENSG00000128272 ENSG00000169047 ENSG00000132855 ENSG00000262243 PMC3082833__F1 During innate immune activation via LPS-LPB-TLR4, a number of factors of the coagulation pathway are activated, creating the cooperative immuno-coagulative response ENSG00000145604 ENSG00000104856 ENSG00000170458 ENSG00000134982 ENSG00000163914 ENSG00000172936 ENSG00000157625 ENSG00000136869 ENSG00000175104 PMC8698202__F1 Feline Coronavirus and Alpha-Herpesvirus Infections: Innate Immune Response and Immune Escape Mechanisms ENSG00000183735 ENSG00000172936 ENSG00000276561 PMC6530577__F1 Endoplasmic Reticulum Stress in Metabolic Liver Diseases and Hepatic Fibrosis ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC10137218__F4 WNK kinases regulate HCO3− versus Cl− secretion across human airway epithelia ENSG00000143867 ENSG00000060237 ENSG00000165238 PMC6309157__F2 Molecular pathways that play central roles in mounting an immune response PMC5787570__F6 Inclusion membrane proteins and secreted effectors from C ENSG00000143761 ENSG00000129515 PMC7231511__F1 MHC cross-dressing can promote interaction between helper or regulatory CD4+ T cells and effector T cells ENSG00000134982 PMC10933445__F6 Model depicting the reciprocal interplay between miR-579-3p and MITF in BRAF-mutant melanoma cells through the modulation of MAPK signaling pathway ENSG00000157764 PMC9290522__F3 Pathogenic Mechanism and Multi-omics Analysis of Oral Manifestations in COVID-19 ENSG00000088888 ENSG00000105397 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000276561 PMC10452344__F1 Influence of microRNAs on the hippo signaling pathway in gliomas ENSG00000186575 ENSG00000131023 PMC11953571__F3 Exercise activates the EGFR/insulin signaling ENSG00000142192 ENSG00000141639 PMC8058408__F5 Pi3K-Akt and IL-17 signaling pathway (A) PI3K-Akt signaling pathway and (B) IL-17 signaling pathway, with key target genes in the yellow box ENSG00000002330 ENSG00000069482 ENSG00000167513 ENSG00000186716 ENSG00000198793 ENSG00000134121 ENSG00000119912 PMC7825454__F7 Proposed signaling pathways regulated by HSV-2 infection and TRIM26 activation ENSG00000183735 PMC8659385__F4 Unlocking the Mechanisms of Cutaneous Adverse Drug Reactions: Activation of the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway by EGFR Inhibitors Triggers Keratinocyte Differentiation and Polarization of Epidermal Immune Responses ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC8659385__F1 Unlocking the Mechanisms of Cutaneous Adverse Drug Reactions: Activation of the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway by EGFR Inhibitors Triggers Keratinocyte Differentiation and Polarization of Epidermal Immune Responses ENSG00000002330 PMC3775863__F3 MicroRNA ‘signature’ during estrogen-mediated mammary carcinogenesis and its reversal by ellagic acid intervention ENSG00000182718 ENSG00000169554 ENSG00000102531 ENSG00000159322 ENSG00000108551 ENSG00000115904 ENSG00000149294 ENSG00000171791 ENSG00000073921 ENSG00000175029 ENSG00000139625 ENSG00000118971 ENSG00000121879 ENSG00000136807 ENSG00000113328 ENSG00000070367 ENSG00000174233 ENSG00000151239 ENSG00000285070 ENSG00000105810 ENSG00000169180 ENSG00000175175 PMC7858612__F2 Ferroptosis: mechanisms and links with diseases ENSG00000196839 ENSG00000111684 ENSG00000115107 PMC7858612__F3 Ferroptosis: mechanisms and links with diseases ENSG00000167468 ENSG00000197429 ENSG00000113161 PMC4501067__F9 Biosynthesis pathway of neurotransmitters in insects ENSG00000087085 ENSG00000140287 ENSG00000170893 ENSG00000115419 PMC5173258__F1 Ivermectin induces cytostatic autophagy by blocking the PAK1-AKT axis in breast cancer cells ENSG00000126775 ENSG00000149269 ENSG00000198793 PMC11383172__F2 IBT induced downstream upregulation of the TNFA pathway in human neutrophils ENSG00000167207 ENSG00000102871 ENSG00000163739 ENSG00000164305 ENSG00000078747 ENSG00000125538 ENSG00000056558 ENSG00000163734 ENSG00000164400 ENSG00000128342 ENSG00000168404 ENSG00000064012 ENSG00000026103 ENSG00000081041 ENSG00000007908 ENSG00000168040 ENSG00000125347 ENSG00000127191 ENSG00000073756 ENSG00000169245 ENSG00000226275 ENSG00000108691 ENSG00000118503 ENSG00000164136 ENSG00000184371 ENSG00000131323 ENSG00000115009 PMC4273126__F3 Molecular mechanisms of alcoholic fibrosis ENSG00000130649 ENSG00000185591 PMC3775578__F1 Novel investigational drugs for basal cell carcinoma ENSG00000128602 PMC1594921__F6 Immunological regulatory IL-10 and MAP kinase pathways ENSG00000132906 ENSG00000157557 ENSG00000172680 ENSG00000124882 ENSG00000130522 ENSG00000196839 ENSG00000177606 ENSG00000065559 ENSG00000187266 ENSG00000175104 ENSG00000073756 ENSG00000139687 PMC9148969__F8 Survival of HT29 Cancer Cells Is Affected by IGF1R Inhibition via Modulation of Self-DNA-Triggered TLR9 Signaling and the Autophagy Response ENSG00000239732 ENSG00000002330 ENSG00000171791 ENSG00000146648 ENSG00000140443 PMC1594921__F5 Presymptomatic and symptomatic infections including the inflammatory cytokines TNFA, IFNG, and ILB ENSG00000064393 ENSG00000173039 ENSG00000232326 ENSG00000173083 ENSG00000162924 ENSG00000043462 ENSG00000166278 ENSG00000019582 ENSG00000150782 ENSG00000111537 ENSG00000170458 ENSG00000185201 ENSG00000167996 ENSG00000158825 ENSG00000026103 PMC8147802__F2 Pluripotency and Growth Factors in Early Embryonic Development of Mammals: A Comparative Approach ENSG00000171791 ENSG00000121966 PMC8016624__F4 miRNAs involved in the autophagy pathways ENSG00000144895 ENSG00000198793 ENSG00000167965 ENSG00000145782 PMC7761462__F1 Angiogenesis-related functions of the Wnt/Beta-catenin signaling pathway in colorectal cancer (CRC) ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC5679442__F1 Stromal niche for epithelial stem cells: a template for regeneration and a brake on malignancy ENSG00000019991 ENSG00000112964 ENSG00000140285 ENSG00000164690 PMC8016624__F1 MicroRNAs (miRs) that regulate the apoptotic signaling pathways ENSG00000120868 ENSG00000168040 PMC3051378__F5 Resulting endoplasmic reticulum (ER) stress and unfolded protein response (UPR) gene network from a modelling approach using the set of differentially regulated genes common to all pancreatic cancer cell lines after nemorosone treatment ENSG00000153094 ENSG00000159388 ENSG00000135446 ENSG00000177606 ENSG00000175592 ENSG00000176153 ENSG00000164305 ENSG00000070669 PMC9271835__F1 Thiol Modifications in the Extracellular Space—Key Proteins in Inflammation and Viral Infection ENSG00000189403 ENSG00000172936 ENSG00000175104 ENSG00000105227 PMC4231685__F9 Metabolic and transcriptional profiles for components of the TCA cycle (A) and BCAA biosynthetic pathway (B) ENSG00000100412 ENSG00000146701 PMC8354730__F2 Perioperative Sleep Disturbance in Postoperative Neurocognitive Disorders ENSG00000136869 ENSG00000062485 ENSG00000171885 PMC4127235__F2 Beta-Catenin is an antagonist of the NFKB pathway ENSG00000281324 ENSG00000162337 ENSG00000168036 PMC11856472__F3 Crosstalk between Wnt, Notch, TGFB, BMP, and Hedgehog signaling pathways ENSG00000163637 ENSG00000170365 ENSG00000134982 ENSG00000173218 ENSG00000136997 ENSG00000168036 ENSG00000114315 ENSG00000128602 PMC10537413__F4 Unraveling MYC’s Role in Orchestrating Tumor Intrinsic and Tumor Microenvironment Interactions Driving Tumorigenesis and Drug Resistance ENSG00000136807 ENSG00000141867 ENSG00000055483 ENSG00000198793 ENSG00000136997 ENSG00000048028 ENSG00000277273 ENSG00000166851 PMC11707140__F5 Dysregulated expression of genes associated with neurovascular coupling ENSG00000129219 ENSG00000123700 ENSG00000095303 ENSG00000073756 PMC4127235__F1 Wnt/Beta-catenin pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC2778230__F3 Apoptotic signaling in aging muscles ENSG00000102871 ENSG00000120868 ENSG00000168040 PMC7564842__F2 Signaling crosstalk between the KRAS and NFKB pathways ENSG00000183735 ENSG00000144118 ENSG00000125538 ENSG00000172936 PMC5679229__F3 Nitric oxide - the forgotten child of tumor metabolism ENSG00000169710 ENSG00000115419 PMC11117676__F2 The nuclear signaling pathway of RIP-mediated EpCAM ENSG00000138795 ENSG00000119888 PMC8213731__F8 Inhibition of discoidin domain receptors by imatinib prevented pancreatic fibrosis demonstrated in experimental chronic pancreatitis model ENSG00000162733 PMC9403516__F8 Astragaloside IV promotes pharmacological effect of Descurainia sophia seeds on isoproterenol-induced cardiomyopathy in rats by synergistically modulating the myosin motor ENSG00000175206 ENSG00000140416 PMC9685729__F2 Noonan syndrome: improving recognition and diagnosis ENSG00000110395 ENSG00000143622 ENSG00000166068 ENSG00000108061 ENSG00000196712 ENSG00000179295 PMC9935929__F5 Signaling pathways in rheumatoid arthritis: implications for targeted therapy ENSG00000198793 ENSG00000168036 ENSG00000010671 PMC5454641__F1 mTOR Signaling Pathway PMC5347766__F9 PICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathway ENSG00000149311 ENSG00000197713 PMC4859092__F1 Workflow of the PSF-SOM method as applied to lung diseases ENSG00000132478 PMC7974515__F7 Graphic summary of this study ENSG00000105329 PMC4859092__F8 Community detection in the lung disease graph PMC2773833__F3 Drivers of senescence and therapeutic opportunities in WS and HGPs ENSG00000149311 ENSG00000175054 PMC4602270__F6 Label-free Quantitative Analysis of Changes in Broiler Liver Proteins under Heat Stress using SWATH-MS Technology ENSG00000132196 ENSG00000133110 ENSG00000133710 ENSG00000100448 ENSG00000145192 ENSG00000173786 ENSG00000147100 ENSG00000197943 ENSG00000140092 ENSG00000164120 ENSG00000291944 PMC6527386__F1 Molecular factors involved in cell migration ENSG00000164828 ENSG00000070831 PMC7597513__F2 This is a simplified version of the canonical nuclear factor kappa B cell (NFKB) pathway that is negatively regulated by A20 binding inhibitor of NFKB (ABIN1) function ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC3743959__F1 Toll-Like Receptor (TLR)-Associated Sequence Variants and Prostate Cancer Risk among Men of African Descent ENSG00000170458 ENSG00000109320 ENSG00000134070 ENSG00000172936 ENSG00000198670 ENSG00000150455 ENSG00000175104 ENSG00000090376 ENSG00000164305 ENSG00000010671 PMC4596921__F1 mtROS in bacterially triggered immune responses ENSG00000115415 ENSG00000130159 ENSG00000168404 ENSG00000175104 ENSG00000247077 PMC6013556__F1 Pathway activation after damage-associated molecular patterns (DAMPs) stimulation ENSG00000170458 ENSG00000189403 ENSG00000172936 ENSG00000136869 ENSG00000184216 PMC3914352__F10 Flow diagram representing the molecular interactions in the Toll-like receptor signaling pathway (from KEGG database) ENSG00000239732 ENSG00000170458 ENSG00000172936 ENSG00000150455 ENSG00000175104 ENSG00000164342 PMC4115628__F2 Sphingolipid metabolism ENSG00000173599 ENSG00000102172 ENSG00000062485 PMC12210125__F3 Tumor cell-macrophage interactions reprogram M2 TAM polarization ENSG00000163464 ENSG00000108691 ENSG00000099812 ENSG00000198492 ENSG00000175832 ENSG00000139372 ENSG00000169429 ENSG00000128342 ENSG00000168610 ENSG00000136231 PMC4424324__F7 Integrin-mediated signaling pathway that regulates actin polymerization, actin cytoskeleton remodeling, and microcluster formation ENSG00000070831 PMC12210125__F2 Signaling pathways for the polarization of TAMs towards the M1 phenotype ENSG00000168062 ENSG00000128917 ENSG00000198492 ENSG00000163565 ENSG00000137265 PMC5133779__F4 Differentially expressed proteins involved in HIF-1 signal pathway ENSG00000134086 ENSG00000108515 ENSG00000072274 ENSG00000136869 PMC8616465__F1 Impact of Chromatin Dynamics and DNA Repair on Genomic Stability and Treatment Resistance in Pediatric High-Grade Gliomas ENSG00000051180 ENSG00000138385 ENSG00000106546 PMC7427779__F8 Schematic summary of this study ENSG00000120690 PMC6121518__F1 Crosstalk between Hh signaling and autophagy based on current evidence ENSG00000161905 ENSG00000106571 ENSG00000144895 ENSG00000198793 ENSG00000164690 ENSG00000139549 ENSG00000128602 ENSG00000163501 ENSG00000275565 ENSG00000062716 PMC11901361__F2 Proposed FRAlpha-mediated endocytosis and signaling pathways in cells ENSG00000168610 PMC6563035__F1 PD-L1 reverse signaling in tumor cells and macrophages ENSG00000111537 PMC10357943__F3 Shining a light on the dark proteome: Non‐canonical open reading frames and their encoded miniproteins as a new frontier in cancer biology ENSG00000117020 ENSG00000291971 ENSG00000048028 ENSG00000168610 ENSG00000146648 ENSG00000214194 ENSG00000163507 ENSG00000109670 PMC10757071__F5 Significance of long non-coding RNAs in the pathogenesis, diagnosis and treatment of inflammatory bowel disease ENSG00000105329 ENSG00000136869 ENSG00000028137 PMC2586335__F1 Ras signalling pathways ENSG00000002330 ENSG00000177606 PMC12052831__F1 FAS mediates apoptosis, inflammation, and treatment of pathogen infection ENSG00000168040 ENSG00000026103 PMC4708176__F2 ERK and non-ERK mediated non-genomic AR signaling ENSG00000291971 ENSG00000129214 ENSG00000150907 ENSG00000198793 PMC7794986__F2 Molecular basis of chemoresistance in GBM ENSG00000165891 ENSG00000170430 ENSG00000185591 PMC11333789__F6 Effect of rotenone on regulating the Nrf2 signaling pathway and induction of Parkinson’s disease was proposed ENSG00000182511 PMC12052831__F2 FAS mediates apoptosis, inflammation, and treatment of pathogen infection ENSG00000137275 ENSG00000291971 ENSG00000138798 ENSG00000157625 ENSG00000168040 ENSG00000074771 ENSG00000168610 ENSG00000026103 PMC11044150__F10 Modulating the MAPK signaling pathway of LQZ against AD ENSG00000138798 ENSG00000172936 ENSG00000175104 PMC7956987__F1 IL-18 signaling pathway ENSG00000172936 ENSG00000175104 ENSG00000137496 PMC11972507__F6 ceRNA Network of m6A-modified circRNAs in OSA-induced Cardiac Injury ENSG00000158604 ENSG00000102606 ENSG00000135127 ENSG00000205643 ENSG00000087903 ENSG00000127526 ENSG00000160408 ENSG00000142453 ENSG00000175592 ENSG00000173064 ENSG00000168040 ENSG00000149182 ENSG00000167130 ENSG00000143512 ENSG00000166428 ENSG00000163904 ENSG00000174996 ENSG00000111652 ENSG00000206527 ENSG00000139190 ENSG00000162073 ENSG00000100647 ENSG00000104325 PMC10869798__F2 Microglial activation and neurodegeneration ENSG00000125538 PMC7784643__F1 Canonical and non-canonical signaling pathways of AhR ENSG00000291971 ENSG00000106546 PMC3632094__F8 The process of LC3-associated phagocytosis (LAP) ENSG00000285379 ENSG00000057663 PMC4468438__F1 Major pathways for the metabolism of IFO ENSG00000165841 ENSG00000197408 PMC9317256__F1 Biosynthesis of Non-Endogenous Apocarotenoids in Transgenic Nicotiana glauca ENSG00000166278 PMC8834185__F2 Cytoskeletal Remodelling as an Achilles’ Heel for Therapy Resistance in Melanoma ENSG00000149269 PMC9022980__F1 TNF-induced necroptosis occurs when upstream pro-survival and pro-apoptotic pathways are inhibited ENSG00000137275 ENSG00000102871 ENSG00000166278 ENSG00000168040 ENSG00000127191 ENSG00000285379 PMC3637854__F2 Overview of UPR signaling ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC2582196__F2 Classic renin-angiotensin-aldosterone system (RAAS) pathway and angiotensin II (Ang II)/insulin signaling in the vascular smooth muscle cell ENSG00000169047 PMC4651655__F1 Mevalonate pathway, NHRs and immunity ENSG00000160752 ENSG00000110921 ENSG00000112972 ENSG00000082175 ENSG00000116133 ENSG00000143815 ENSG00000172893 ENSG00000113161 ENSG00000104549 ENSG00000167508 ENSG00000075239 ENSG00000069667 PMC3665263__F2 Innate immune system in pneumococcal meningitis infection ENSG00000162711 ENSG00000239732 ENSG00000163568 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC2702319__F4 Distributions of the orthologous gene groups containing duplicate genes that arose through 3R-WGD (shown as gray boxes) in the network diagrams ENSG00000131473 ENSG00000152495 ENSG00000125246 ENSG00000105953 ENSG00000091140 ENSG00000062485 PMC6158718__F1 PI3K/AKT pathway ENSG00000002330 ENSG00000169047 ENSG00000136997 PMC7052015__F1 Detailed illustration of the experiment ENSG00000178573 ENSG00000079999 PMC6158718__F2 PI3K/AKT pathway in muscle tissue when normal state and insulin resistance ENSG00000042832 ENSG00000284161 PMC7843693__F4 Therapeutic potential of mesenchymal stem cells in treating both types of diabetes mellitus and associated diseases ENSG00000178860 ENSG00000169047 PMC5660598__F4 Dexamethasone (Dex) and monphosphoryl lipid A (MPLA) treatment leads to changes in the expression of genes involved in biological processes associated with immune response regulation ENSG00000161905 ENSG00000143546 ENSG00000275385 ENSG00000187608 ENSG00000125148 ENSG00000163220 ENSG00000158517 ENSG00000143226 ENSG00000243509 ENSG00000179593 ENSG00000172183 ENSG00000171051 ENSG00000137801 ENSG00000157557 ENSG00000260314 ENSG00000170458 ENSG00000136997 ENSG00000100979 ENSG00000272398 ENSG00000291905 ENSG00000168685 ENSG00000169508 PMC11214942__F5 Harnessing the potential of hydrogels for advanced therapeutic applications: current achievements and future directions ENSG00000291971 ENSG00000103335 PMC11214942__F4 Harnessing the potential of hydrogels for advanced therapeutic applications: current achievements and future directions ENSG00000002330 PMC10970410__F12 LncRNAs potentially involved in the immaturity-stemness regulation processes in the human keratinocyte lineage ENSG00000137834 ENSG00000095739 ENSG00000140285 ENSG00000111186 ENSG00000162924 ENSG00000136826 PMC10971967__F6 Proteomics analysis of gastrocnemius and soleus muscle in the ET group ENSG00000143318 ENSG00000005882 ENSG00000188229 ENSG00000134871 ENSG00000004779 ENSG00000131828 ENSG00000283100 ENSG00000149089 ENSG00000175198 ENSG00000272573 ENSG00000114054 ENSG00000108821 ENSG00000146701 ENSG00000024422 ENSG00000159399 PMC6406375__F1 Major calcium channels, pumps, exchangers and sensors in mammalian cells ENSG00000167323 ENSG00000293604 ENSG00000156026 ENSG00000084774 PMC7459397__F1 FGF18‐induced ER‐phagy in chondrocytes ENSG00000160867 ENSG00000169047 ENSG00000156427 ENSG00000112561 PMC4344885__F6 Endocardial Fibroelastosis is Caused by Aberrant Endothelial to Mesenchymal Transition ENSG00000170365 ENSG00000138798 PMC3426835__F5 Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis ENSG00000142192 PMC6160488__F4 Crosstalk between the interferon signaling pathway and PD-L1 signalosome ENSG00000101407 ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000115415 ENSG00000103043 ENSG00000168610 ENSG00000164305 ENSG00000083642 ENSG00000196712 ENSG00000142166 PMC10838202__F5 mRNA-seq results of KEGG pathway enrichment analysis and western blot results ENSG00000142192 ENSG00000198517 ENSG00000150455 PMC3961774__F5 Role of Heme Oxygenase-1 in Postnatal Differentiation of Stem Cells: A Possible Cross-Talk with MicroRNAs ENSG00000178860 ENSG00000128272 ENSG00000125398 ENSG00000168036 ENSG00000131196 PMC3179275__F4A Integrative computational biology for cancer research ENSG00000177606 ENSG00000099942 PMC6197618__F6 RHBDF1-facilitated membrane trafficking of pro-TGFA via CCV pathway ENSG00000100280 ENSG00000163235 ENSG00000007384 ENSG00000146648 PMC5341867__F2 TP53 mutation hits energy metabolism and increases glycolysis in breast cancer ENSG00000141349 ENSG00000130957 ENSG00000135423 ENSG00000074800 ENSG00000108515 ENSG00000067057 ENSG00000131482 ENSG00000278373 ENSG00000153574 ENSG00000152556 PMC8176240__F6 Comprehensive evaluation of microRNA-10b in digestive system cancers reveals prognostic implication and signaling pathways associated with tumor progression ENSG00000132906 ENSG00000002330 ENSG00000051180 ENSG00000168610 ENSG00000122008 ENSG00000139618 PMC4128997__F3 PPAR signaling pathway ENSG00000150991 ENSG00000100979 PMC4128997__F2 Antigen processing and presentation pathway ENSG00000111537 ENSG00000127022 ENSG00000273686 ENSG00000231925 PMC3256879__F8 A hypothetical diagram of the involvement of ATF6 in BMP2-induced osteoblast differentiation PMC5650102__F2 T Cell Signaling and Gene Regulation Defects in Systemic Lupus Erythematosus (SLE) ENSG00000198793 ENSG00000137265 ENSG00000026508 ENSG00000168610 PMC2846061__F3 Ovary: basic biology and clinical implications ENSG00000109321 ENSG00000291971 ENSG00000106483 ENSG00000118971 ENSG00000163661 ENSG00000073756 ENSG00000132639 ENSG00000127129 ENSG00000123999 ENSG00000170365 ENSG00000170961 ENSG00000159216 ENSG00000130385 ENSG00000082175 ENSG00000124882 ENSG00000146648 ENSG00000123610 PMC9409119__F2 Emerging Key Role of the mGluR1-PKCG Signaling Pathway in the Pathogenesis of Spinocerebellar Ataxias: A Neurodevelopmental Viewpoint ENSG00000135824 ENSG00000068383 PMC11284857__F3 Disturbance of DFC signaling pathways results in disorders of osteoclast differentiation ENSG00000120149 PMC9409119__F1 Emerging Key Role of the mGluR1-PKCG Signaling Pathway in the Pathogenesis of Spinocerebellar Ataxias: A Neurodevelopmental Viewpoint ENSG00000135824 ENSG00000068383 ENSG00000138741 PMC10982379__F2 Ferroptosis by PI3K/Akt signaling pathway: a promising therapeutic axis in cancer ENSG00000198793 ENSG00000171791 PMC10982379__F1 Ferroptosis by PI3K/Akt signaling pathway: a promising therapeutic axis in cancer ENSG00000161905 ENSG00000167468 ENSG00000111684 ENSG00000115107 ENSG00000115419 PMC10982379__F4 Ferroptosis by PI3K/Akt signaling pathway: a promising therapeutic axis in cancer ENSG00000114770 ENSG00000081181 ENSG00000151012 ENSG00000167468 ENSG00000008394 ENSG00000168610 PMC10982379__F3 Ferroptosis by PI3K/Akt signaling pathway: a promising therapeutic axis in cancer ENSG00000151012 ENSG00000167468 PMC8298031__F2 In vitro Assays and Imaging Methods for Drug Discovery for Cardiac Fibrosis ENSG00000105329 PMC10982379__F6 Ferroptosis by PI3K/Akt signaling pathway: a promising therapeutic axis in cancer ENSG00000114770 ENSG00000100422 ENSG00000148346 ENSG00000111537 ENSG00000151012 ENSG00000167468 ENSG00000167996 PMC3121540__F4 A gene network shows that mRNA levels of PDGFR and ECM-related genes are significantly correlated in human breast cancer ENSG00000087245 ENSG00000117122 ENSG00000113140 ENSG00000166147 PMC10982379__F5 Ferroptosis by PI3K/Akt signaling pathway: a promising therapeutic axis in cancer ENSG00000111684 ENSG00000142082 ENSG00000115107 PMC9657596__F6 Lactucin, a Bitter Sesquiterpene from Cichorium intybus, Inhibits Cancer Cell Proliferation by Downregulating the MAPK and Central Carbon Metabolism Pathway PMC10845554__F1 IL-17-producing Treg differentiation ENSG00000157933 ENSG00000030419 ENSG00000134982 ENSG00000123411 ENSG00000163599 ENSG00000108654 ENSG00000049768 ENSG00000168610 ENSG00000106546 ENSG00000178573 ENSG00000136869 ENSG00000126353 ENSG00000112486 PMC8833974__F5 KRAS as a Modulator of the Inflammatory Tumor Microenvironment: Therapeutic Implications ENSG00000049768 PMC4323371__F1 TERRA regulation of telomere length for the protection of chromosome ends involving TRF2 ENSG00000149311 ENSG00000102974 PMC5316868__F2 Pervasive translational regulation of the cell signalling circuitry underlies mammalian development ENSG00000167601 ENSG00000125734 ENSG00000143147 ENSG00000157404 ENSG00000106123 ENSG00000169071 ENSG00000152749 ENSG00000130758 ENSG00000181619 ENSG00000141639 ENSG00000166856 ENSG00000185483 ENSG00000105647 ENSG00000181409 ENSG00000148358 ENSG00000069956 ENSG00000169032 ENSG00000166484 ENSG00000135341 ENSG00000100485 ENSG00000137764 ENSG00000173264 ENSG00000164879 ENSG00000170775 ENSG00000149269 ENSG00000128052 ENSG00000166501 ENSG00000182580 ENSG00000154928 ENSG00000169508 ENSG00000184194 ENSG00000171105 ENSG00000065361 ENSG00000102195 ENSG00000274205 ENSG00000133216 ENSG00000196411 ENSG00000164742 ENSG00000153208 ENSG00000175697 ENSG00000067606 ENSG00000134853 ENSG00000177464 ENSG00000188130 ENSG00000180758 ENSG00000171608 ENSG00000146648 ENSG00000171533 PMC6139250__F1 NFKB signal transduction pathway ENSG00000104856 ENSG00000087245 ENSG00000115008 ENSG00000163739 ENSG00000186716 ENSG00000136997 ENSG00000056558 ENSG00000173039 ENSG00000123374 ENSG00000100985 ENSG00000162692 ENSG00000127191 PMC9928209__F2 Tanshinone IIA and hepatocellular carcinoma: A potential therapeutic drug ENSG00000135446 ENSG00000198793 ENSG00000189403 ENSG00000123374 ENSG00000105810 PMC3970201__F2 Self-consumption: the interplay of autophagy and apoptosis ENSG00000291971 ENSG00000145782 PMC5316868__F3 Pervasive translational regulation of the cell signalling circuitry underlies mammalian development ENSG00000113645 ENSG00000107404 ENSG00000138002 ENSG00000186575 ENSG00000187240 ENSG00000173040 ENSG00000117425 ENSG00000134982 ENSG00000197102 ENSG00000164690 ENSG00000128602 PMC5837968__F6 Schematic illustration of SFKs mechanism of action in interferon regulatory factor 1 (IRF-1) K63-Ubiquitination ENSG00000125347 ENSG00000175104 PMC6943360__F1 An overview of MIF signaling pathways: MIFs interactions can contribute to the formation of cancer and neural development ENSG00000019582 ENSG00000002330 ENSG00000026508 ENSG00000121966 PMC3673040__F1 Leptin is generated in adipose tissue and transported via the bloodstream to the hypothalamus ENSG00000115138 ENSG00000175426 ENSG00000166603 PMC3763758__F1 HIV-related neuropathic pain pathway ENSG00000121966 PMC8953969__GA STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS) ENSG00000278718 ENSG00000162711 ENSG00000124256 ENSG00000183735 ENSG00000164430 ENSG00000137275 ENSG00000163568 ENSG00000168404 ENSG00000164305 ENSG00000285379 ENSG00000142166 PMC7444278__F3 Major components of the vertebrate Hedgehog pathway are dynamically localized to the primary cilium in response to Hedgehog ligand ENSG00000143147 ENSG00000166813 ENSG00000128602 PMC2902748__F1 Hsp90-dependent modulation of proangiogenic signaling pathways in cancer ENSG00000019991 ENSG00000142627 ENSG00000157933 ENSG00000138798 ENSG00000198793 ENSG00000146648 PMC10525272__F6 Platelet activation pathway confirmed in the KEGG pathway analysis ENSG00000180210 ENSG00000105664 ENSG00000110799 ENSG00000010810 ENSG00000115718 ENSG00000111816 PMC10525272__F5 Canine Somatic Mutations from Whole-Exome Sequencing of B-Cell Lymphomas in Six Canine Breeds—A Preliminary Study ENSG00000124102 ENSG00000182533 ENSG00000130528 ENSG00000156026 ENSG00000186716 PMC10525272__F4 Vascular smooth muscle contraction pathway confirmed in the KEGG pathway analysis ENSG00000160013 ENSG00000148926 ENSG00000173786 ENSG00000151617 ENSG00000084774 PMC9371824__F12 Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury ENSG00000170458 ENSG00000172005 ENSG00000136869 ENSG00000175104 PMC8062757__F1 Schematic diagram showing FST modulation of TGFB/Samd 3 signaling pathway during adipose browning ENSG00000111049 ENSG00000134363 ENSG00000135414 PMC8418449__F4 Interplay Between Reactive Oxygen/Reactive Nitrogen Species and Metabolism in Vascular Biology and Disease ENSG00000180210 ENSG00000157426 ENSG00000065833 ENSG00000213658 ENSG00000092621 ENSG00000113161 ENSG00000078237 PMC10946270__F3 Classical and alternative pathways of NF-KB signalling are mediated by a variety of receptors and signalling molecules, including TLR, CD30L, CD40L, RANKL, etc ENSG00000104856 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000198286 PMC7064735__F3 Molecular mechanisms underlying PM2.5-induced defective airway epithelial host defense functions ENSG00000146648 PMC3164721__F1 Phospholipase C Isozymes Are Deregulated in Colorectal Cancer – Insights Gained from Gene Set Enrichment Analysis of the Transcriptome ENSG00000157764 ENSG00000109101 ENSG00000134982 ENSG00000163914 ENSG00000121879 PMC9172986__F6 An approach to cellular tropism of SARS-CoV-2 through protein–protein interaction and enrichment analysis ENSG00000101751 ENSG00000177971 ENSG00000145912 ENSG00000241945 ENSG00000262788 ENSG00000110799 ENSG00000136718 ENSG00000101361 ENSG00000169251 ENSG00000180210 ENSG00000164338 ENSG00000101981 ENSG00000141101 ENSG00000166169 PMC9172986__F5 An approach to cellular tropism of SARS-CoV-2 through protein–protein interaction and enrichment analysis ENSG00000172680 ENSG00000182180 ENSG00000185591 ENSG00000105402 ENSG00000127948 PMC5067532__F3 Hydrogen sulfide in DN ENSG00000198793 ENSG00000086991 PMC5389977__F3 Release of growth hormone (GH), Wnt, or RANKL, as stimulated by progesterone (P4), promotes interaction with various signal transduction pathways ENSG00000138795 ENSG00000112964 ENSG00000138798 ENSG00000198793 ENSG00000168036 ENSG00000146648 PMC5335555__F6 CD61 promotes the differentiation of canine ADMSCs into PGC-like cells through modulation of TGFB signaling ENSG00000147596 ENSG00000291971 PMC5389977__F4 Interaction of HER-activated pathways with canonical Wnt signaling ENSG00000019991 ENSG00000291971 ENSG00000134982 ENSG00000138798 ENSG00000168036 PMC4814376__F1 Summary of metabolic FGFs ENSG00000160867 ENSG00000105550 ENSG00000077782 PMC9676213__F7 MS-proteomics provides insight into the host responses towards alginate microspheres ENSG00000274619 ENSG00000003436 ENSG00000291559 ENSG00000000971 ENSG00000120885 ENSG00000244731 ENSG00000166278 ENSG00000115718 ENSG00000122194 ENSG00000132693 PMC9685611__F2 Ovarian cancer stem cells: Critical roles in anti-tumor immunity ENSG00000163599 ENSG00000026508 ENSG00000172936 PMC4176146__F1 The hexosamine biosynthetic pathway and O-GlcNAcylation are shown ENSG00000100473 ENSG00000147162 ENSG00000198408 PMC7434989__F2 Emerging roles for the IL-6 family of cytokines in pancreatic cancer ENSG00000168610 PMC7264916__F1 Mutations and signaling pathways in vascular anomalies ENSG00000196411 ENSG00000170365 ENSG00000198793 ENSG00000169032 ENSG00000114209 ENSG00000121879 ENSG00000163217 PMC8508931__F5 Comparative Phosphoproteomic Analysis Reveals the Response of Starch Metabolism to High-Temperature Stress in Rice Endosperm ENSG00000018510 ENSG00000167701 PMC4331812__F5 Metabolic flux map of central carbon metabolism in cotyledons at early seed fill ENSG00000159921 ENSG00000172005 ENSG00000171759 PMC3513650__F1 BRCA and RAD52 pathways of DNA double-strand break (DSB) repair ENSG00000083093 ENSG00000051180 ENSG00000139618 PMC8418449__F6 Interplay Between Reactive Oxygen/Reactive Nitrogen Species and Metabolism in Vascular Biology and Disease ENSG00000180210 ENSG00000228716 ENSG00000113161 PMC6600513__F1A Signal Exchange through Extracellular Vesicles in Neuromuscular Junction Establishment and Maintenance: From Physiology to Pathology ENSG00000180210 ENSG00000134569 ENSG00000134982 ENSG00000030304 PMC8071006__F6 Induced Torpor as a Countermeasure for Low Dose Radiation Exposure in a Zebrafish Model ENSG00000141086 ENSG00000086730 PMC3603147__F7 Inhibition of Na+-K+-2Cl− cotransporter isoform 1 accelerates temozolomide-mediated apoptosis in glioblastoma cancer cells ENSG00000122966 ENSG00000143867 PMC4833964__F1 Cancer-relevant pathway map ENSG00000198793 ENSG00000168036 PMC5406580__F2 Hypothalamic circuits regulating thermogenesis of BAT and browning of WAT ENSG00000198576 ENSG00000115138 ENSG00000166603 ENSG00000005381 PMC2922475__F1 CD73: A novel target for cancer immunotherapy ENSG00000196839 PMC6387609__F7 Amine derivatives of furocoumarin induce melanogenesis by activating Akt/GSK-3B/Beta-catenin signal pathway ENSG00000168036 PMC5857625__F7 Schematic representation of murine and human gonadal androgen synthesis ENSG00000127948 PMC8056114__F1 NGF-mediated regulation of the NGFR and NTRK1 signaling pathways ENSG00000163914 ENSG00000203710 ENSG00000169783 ENSG00000117322 ENSG00000064300 PMC8805653__F1 IL-33/ST2 pathway and its conceptual role following ischemic stroke ENSG00000137033 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000184216 PMC5031419__F4 Non-overlapping Clinical and Mutational Patterns in Melanomas from the Female Genital Tract and Atypical Genital Nevi ENSG00000157404 ENSG00000002330 ENSG00000157764 ENSG00000291971 ENSG00000135446 ENSG00000139687 PMC6770591__F7 Scheme of the de novo synthesis pathway of glutathione ENSG00000116761 PMC6362810__F3 Multiple nonunidirectional levels through which autophagy-related processes in senescence affect regulation of SASP genes, often via NFkB activation ENSG00000115008 ENSG00000285109 ENSG00000056972 ENSG00000198793 PMC3873730__F3 Transcriptome Analysis of Human Injured Meniscus Reveals a Distinct Phenotype of Meniscus Degeneration with Aging ENSG00000230930 ENSG00000165480 ENSG00000107798 ENSG00000188846 ENSG00000166509 ENSG00000003249 ENSG00000137563 ENSG00000104903 ENSG00000125398 ENSG00000075884 ENSG00000115138 ENSG00000163017 ENSG00000112742 ENSG00000136108 ENSG00000282899 ENSG00000123975 ENSG00000137673 ENSG00000148400 ENSG00000184661 ENSG00000117399 ENSG00000166016 ENSG00000198901 ENSG00000013810 ENSG00000156427 ENSG00000132646 ENSG00000172005 ENSG00000100479 ENSG00000142731 ENSG00000188763 ENSG00000138180 ENSG00000049089 PMC7072559__F2 Metabolic pathways contributing to glutamine addiction in gliomas ENSG00000198793 ENSG00000173599 ENSG00000167701 PMC9511797__F2 Aberrant calcium signalling downstream of mutations in TP53 and the PI3K/AKT pathway genes promotes disease progression and therapy resistance in triple negative breast cancer PMC9511797__F1 Aberrant calcium signalling downstream of mutations in TP53 and the PI3K/AKT pathway genes promotes disease progression and therapy resistance in triple negative breast cancer ENSG00000118515 ENSG00000163993 ENSG00000137672 PMC9313971__F1 Xeroderma Pigmentosum: A Genetic Condition Skin Cancer Correlated—A Systematic Review ENSG00000132646 ENSG00000136936 PMC9928209__F7 Tanshinone IIA and hepatocellular carcinoma: A potential therapeutic drug ENSG00000069482 ENSG00000198793 PMC6280650__F1 Role of the cGAS–STING pathway in cancer development and oncotherapeutic approaches ENSG00000183735 ENSG00000164430 ENSG00000158825 PMC7701511__F3 VEGFA/VEGFR2 system differentially modulates the UPR activation in condition of transient or sustained ER stress ENSG00000144895 ENSG00000112715 PMC2672430__F2 Prodeath or Prosurvival: Two Facets of Hypoxia Inducible Factor-1 in Perinatal Brain Injury ENSG00000134086 PMC8127222__F1 Emerging role of the KCTD proteins in cancer ENSG00000153885 ENSG00000164690 ENSG00000128602 PMC8127222__F2 Emerging role of the KCTD proteins in cancer ENSG00000112078 ENSG00000148400 ENSG00000134982 ENSG00000110906 ENSG00000168036 ENSG00000109079 ENSG00000134504 PMC3046427__F2 Beta-Catenin is at the hub of multiple signaling pathways ENSG00000087095 ENSG00000127445 ENSG00000281324 ENSG00000164736 ENSG00000162337 ENSG00000291971 ENSG00000134982 ENSG00000113558 ENSG00000168036 ENSG00000196470 ENSG00000146648 PMC9619051__F1 Perspectives of herbs and their natural compounds, and herb formulas on treating diverse diseases through regulating complicated JAK/STAT signaling ENSG00000138378 ENSG00000099985 ENSG00000197272 ENSG00000128342 ENSG00000168610 ENSG00000146648 PMC7799431__F1 Importance of Keeping Time in the Liver ENSG00000105835 ENSG00000077463 ENSG00000096717 ENSG00000069667 PMC2903563__F7 Glucose metabolic pathway response ENSG00000074800 ENSG00000152359 PMC11284857__F4 Depicted regions primarily reside within the dental follicle tissue surrounding the root apex ENSG00000169884 PMC7012465__F2 Regulation of hepcidin expression (adapted from Silvestri et al.) ENSG00000170365 ENSG00000010704 ENSG00000106327 ENSG00000187045 ENSG00000178752 ENSG00000136869 ENSG00000168610 PMC3871684__F1 Microfluidic Generated EGF-Gradients Induce Chemokinesis of Transplantable Retinal Progenitor Cells via the JAK/STAT and PI3Kinase Signaling Pathways ENSG00000291971 ENSG00000138798 ENSG00000198793 ENSG00000095015 ENSG00000065559 ENSG00000108443 ENSG00000169032 ENSG00000168610 ENSG00000117322 ENSG00000160691 ENSG00000177606 ENSG00000124181 ENSG00000146648 PMC6098640__F5 The pathway through which IL-33 stimulates the proliferation signaling of CRC cells ENSG00000137033 PMC4730337__F1 EGFR transactivation by GPCR ENSG00000291971 ENSG00000113070 ENSG00000146648 PMC7238533__F2 Role of Fbln7 and its C-terminal fragment in the modulation of cellular functions under physiological and pathological conditions ENSG00000115415 ENSG00000144152 ENSG00000168610 PMC7178193__F2 Adiponectin properties on healthy skeletal muscle ENSG00000157500 ENSG00000169047 ENSG00000159346 PMC4900151__F1 The role of REDD1 in the regulating muscle protein balance in response to acute alcohol ENSG00000177169 PMC4261235__F1 Quantitative Analysis of Robustness of Dynamic Response and Signal Transfer in Insulin mediated PI3K/AKT Pathway ENSG00000124102 ENSG00000169047 ENSG00000087842 PMC5542187__F5 Simplified diagrams of putative signaling pathways responsible for the different migration patterns (i.e ENSG00000070831 ENSG00000198793 PMC6315991__F1 Links between Lipid and Iron Metabolic Pathways ENSG00000131473 ENSG00000182511 ENSG00000104237 ENSG00000089472 ENSG00000149809 ENSG00000109929 ENSG00000105697 ENSG00000113161 ENSG00000115107 PMC3476325__F9 Proposed model for how CCL2 signaling through CCR2 signaling regulates survival and motility of breast cancer cells ENSG00000108691 ENSG00000121807 PMC4114208__F1 Unfolded protein response pathways are shown ENSG00000128272 ENSG00000100219 PMC11659389__F5 STRING protein‒protein interactions between the recognized proteins and our prioritized proteins for each skin cancer ENSG00000157764 ENSG00000167768 ENSG00000111321 ENSG00000047936 ENSG00000102003 ENSG00000221837 ENSG00000186847 ENSG00000101440 ENSG00000163131 ENSG00000164362 ENSG00000099810 ENSG00000159450 ENSG00000164690 ENSG00000128602 ENSG00000164175 ENSG00000274811 PMC8236816__F2 Targeting of Lysosomal Pathway Genes for Parkinson's Disease Modification: Insights From Cellular and Animal Models ENSG00000069329 ENSG00000084733 PMC8236816__F1 Targeting of Lysosomal Pathway Genes for Parkinson's Disease Modification: Insights From Cellular and Animal Models ENSG00000069329 ENSG00000198925 PMC2786705__F8 Continued defect in IRF-3-deficient BMDCs ENSG00000115415 PMC6381377__F6 Deregulated Wnt signaling pathways in the BM of ENU induced experimental leukemic mice ENSG00000154342 ENSG00000169071 ENSG00000170558 ENSG00000168036 PMC4227184__F10 Pathway analysis ENSG00000140992 ENSG00000149269 ENSG00000177606 ENSG00000112715 ENSG00000162692 ENSG00000146648 ENSG00000141968 ENSG00000062485 PMC11064393__F1 CGAS-STING signaling pathway ENSG00000183735 ENSG00000164430 PMC6757413__F4 Important signaling pathways that govern the differentiation of pancreatic conversion and the mechanism of action of different small molecules and peptides reported on pancreatic differentiation from MSC ENSG00000019991 ENSG00000142192 ENSG00000134982 ENSG00000138798 ENSG00000198793 ENSG00000156574 ENSG00000168036 ENSG00000146648 PMC10389822__F2 Intersection of COVID-19 and Rheumatoid Arthritis: Shared Mechanisms, Treatment Challenges, and Potential Therapeutic Approaches ENSG00000141867 ENSG00000173039 ENSG00000168610 PMC8284093__F11 Genomic Response to TGFB1 Dictates Failed Repair and Progression of Fibrotic Disease in the Obstructed Kidney ENSG00000105327 ENSG00000163743 ENSG00000134982 ENSG00000159388 ENSG00000108654 ENSG00000129514 ENSG00000115816 ENSG00000171791 ENSG00000162772 ENSG00000080546 ENSG00000177595 ENSG00000116017 ENSG00000292234 ENSG00000078900 ENSG00000164938 ENSG00000139687 ENSG00000140464 ENSG00000282899 ENSG00000087245 ENSG00000104689 ENSG00000120837 ENSG00000085117 ENSG00000108773 ENSG00000151615 ENSG00000081051 ENSG00000048392 ENSG00000143514 ENSG00000134574 ENSG00000118785 ENSG00000155367 ENSG00000198176 ENSG00000138166 ENSG00000163235 ENSG00000132646 ENSG00000102760 ENSG00000042286 ENSG00000066136 ENSG00000112378 ENSG00000173846 ENSG00000258643 ENSG00000128191 ENSG00000146648 ENSG00000127616 ENSG00000019991 ENSG00000152409 ENSG00000001167 ENSG00000196591 ENSG00000120889 ENSG00000137393 ENSG00000183918 ENSG00000127129 ENSG00000112242 ENSG00000140379 ENSG00000281449 ENSG00000197386 ENSG00000185591 ENSG00000128342 ENSG00000120868 ENSG00000196367 ENSG00000026103 ENSG00000168209 ENSG00000142627 ENSG00000166257 ENSG00000005339 ENSG00000173011 ENSG00000175793 ENSG00000138794 ENSG00000276463 ENSG00000126457 ENSG00000118816 ENSG00000161642 ENSG00000111725 ENSG00000173530 ENSG00000152192 ENSG00000134057 ENSG00000177606 ENSG00000161513 ENSG00000170855 ENSG00000107165 ENSG00000078237 ENSG00000090097 ENSG00000095002 ENSG00000113360 ENSG00000122512 PMC3787304__F1 Different phosphorylation sites on STAT3 mediate canonical and non-canonical functions of the Notch signaling pathway ENSG00000173673 ENSG00000131095 ENSG00000273529 ENSG00000114315 ENSG00000168610 PMC8284093__F10 Genomic Response to TGFB1 Dictates Failed Repair and Progression of Fibrotic Disease in the Obstructed Kidney ENSG00000184990 ENSG00000132906 ENSG00000149311 ENSG00000175054 ENSG00000136997 ENSG00000042286 ENSG00000123374 ENSG00000112378 ENSG00000164305 PMC6895278__F4 Models for REV3-dependent synthesis at difficult-to-replicate regions in the genome ENSG00000132646 ENSG00000051180 PMC8006921__F7 Wnt signaling gene expression profiling in healthy versus asthmatic bronchial fibroblasts generated by PathViso pathway analysis and drawing software ENSG00000167653 ENSG00000127948 PMC11855906__F4 Mechanistic insights and multifaceted applications of autophagy as a potential therapeutic target for metabolic cardiomyopathies ENSG00000177169 ENSG00000105835 ENSG00000137275 ENSG00000008952 ENSG00000288145 ENSG00000167996 ENSG00000158828 ENSG00000133318 ENSG00000171791 ENSG00000168610 ENSG00000275031 PMC11855906__F3 Simplified scheme for the regulation of cardiac selective autophagy in HFD-induced metabolic cardiomyopathy ENSG00000177169 ENSG00000141867 ENSG00000008952 ENSG00000112561 ENSG00000133318 ENSG00000168610 ENSG00000122194 PMC6759601__F5 Schematic overview of gene expression regulation of fatty acid oxidation and tricarboxylic acid (TCA) cycle in tPVAT and IAT ENSG00000042832 ENSG00000115425 ENSG00000073578 ENSG00000117118 ENSG00000163541 ENSG00000105953 ENSG00000172340 ENSG00000101365 ENSG00000205138 ENSG00000143252 ENSG00000117054 ENSG00000213658 ENSG00000178537 ENSG00000115361 ENSG00000122971 ENSG00000113790 ENSG00000146701 ENSG00000091140 ENSG00000138400 ENSG00000167985 ENSG00000062485 PMC11855906__F2 Comprehensive scheme for the complex regulation of cardiac non-selective autophagy in STZ-induced metabolic cardiomyopathy ENSG00000177169 ENSG00000137275 ENSG00000150907 ENSG00000198793 ENSG00000005893 ENSG00000171791 ENSG00000169752 ENSG00000275031 PMC6830338__F1 Transcription regulators (TRs) that modulate glycolytic metabolism in cancer cells ENSG00000198793 ENSG00000078237 PMC11855906__F1 Comprehensive scheme for the complex regulation of cardiac non-selective autophagy in HFD-induced metabolic cardiomyopathy ENSG00000177169 ENSG00000198793 ENSG00000171791 ENSG00000145782 ENSG00000057663 PMC7714584__F6 Target-pathway network ENSG00000169248 ENSG00000169245 ENSG00000118785 ENSG00000149968 ENSG00000125538 ENSG00000203859 ENSG00000100985 ENSG00000073756 ENSG00000118777 PMC8863938__F2 Apoptosis Triggering, an Important Way for Natural Products From Herbal Medicines to Treat Pancreatic Cancers ENSG00000002330 PMC6707069__F8 Influence of extracellular HA in erlotinib efficacy using a reductionist 3D glioblastoma model ENSG00000026508 ENSG00000168610 ENSG00000146648 PMC5387055__F3 Upon antigen encounter T cells differentiate into effector cells ENSG00000163599 ENSG00000198793 ENSG00000136997 ENSG00000124181 PMC8863938__F4 Apoptosis Triggering, an Important Way for Natural Products From Herbal Medicines to Treat Pancreatic Cancers ENSG00000198793 ENSG00000171791 PMC8863938__F3 Apoptosis Triggering, an Important Way for Natural Products From Herbal Medicines to Treat Pancreatic Cancers ENSG00000128272 ENSG00000144895 ENSG00000171791 PMC8863938__F5 Apoptosis Triggering, an Important Way for Natural Products From Herbal Medicines to Treat Pancreatic Cancers PMC7267729__F5 Dysregulation of the Myostatin Pathway in Mtm1−/y MiceThe members of the myostatin pathway analyzed in this manuscript at the mRNA or protein levels are indicated in this figure ENSG00000135414 PMC1435694__F1 Chemistry of the retinoid cycle reactions in the vertebrate retina ENSG00000116745 ENSG00000197713 PMC8063466__F4 Quercetin inhibits overactivation of dormant PMFs induced by Cy ENSG00000104899 ENSG00000198793 PMC9252958__F1 Contribution of specific ceramides to obesity-associated metabolic diseases ENSG00000285281 ENSG00000102172 ENSG00000174607 ENSG00000062282 ENSG00000143418 ENSG00000139624 ENSG00000223802 ENSG00000172292 ENSG00000154227 ENSG00000147869 ENSG00000197142 ENSG00000166224 ENSG00000119537 PMC5403850__F1 Pathological effects of chronic oxidative stress ENSG00000135218 ENSG00000169047 PMC5502164__F1 Methylation cycle pathway: (A) Methionine and homocysteine (Hcys) are generated by the following enzymes: CBS = cystathionine Beta-synthase, MAT = methionine adenosyltransferase, MS = methionine synthase, SAHH = S-adenosylhomocysteine hydrolasa ENSG00000205221 PMC9586738__F1 Correlation of Glucose Metabolism with Cancer and Intervention with Traditional Chinese Medicine ENSG00000180210 ENSG00000198793 ENSG00000136872 PMC7795614__F3A Comparative Proteomics Analysis Reveals Unique Early Signaling Response of Saccharomyces cerevisiae to Oxidants with Different Mechanism of Action ENSG00000132341 PMC9687454__F2 Tirzepatide—Friend or Foe in Diabetic Cancer Patients? ENSG00000198793 ENSG00000010310 ENSG00000140443 PMC5477726__F1 BMP4 signaling pathways ENSG00000107779 ENSG00000170365 ENSG00000137834 ENSG00000183691 ENSG00000204217 PMC3968382__F1 New anti-complement drugs: not so far away PMC12112211__F6 Activation of T cells by dendritic cells in lymph nodes; (B) binding of T cells to tumor cells inducing apoptosis; (C) signaling pathways for activation of cell growth and proliferation or signaling pathways for cycle arrest or apoptosis ENSG00000132906 ENSG00000115415 ENSG00000134982 ENSG00000168040 ENSG00000064012 ENSG00000026103 PMC5095497__F7 Role of the citrate pathway in Down syndrome (DS) ENSG00000131473 ENSG00000178537 ENSG00000079432 PMC3195227__F1 A schematic diagram of the kynurenine pathway PMC8959454__F1 Drug Discovery of DKK1 Inhibitors ENSG00000134982 ENSG00000177606 ENSG00000168036 ENSG00000136026 PMC3342334__F9 Interaction between Early Life Epilepsy and Autistic-Like Behavioral Consequences: A Role for the Mammalian Target of Rapamycin (mTOR) Pathway ENSG00000198576 PMC4138453__F3 Metabolic pathway of arachidonic acid via 5- lipoxygenase ENSG00000226275 PMC3357406__F3 Divergent Genomic and Epigenomic Landscapes of Lung Cancer Subtypes Underscore the Selection of Different Oncogenic Pathways during Tumor Development ENSG00000136492 ENSG00000156735 ENSG00000164062 ENSG00000181788 ENSG00000105329 ENSG00000114030 ENSG00000041802 ENSG00000130159 ENSG00000184916 ENSG00000154447 ENSG00000283082 ENSG00000141867 ENSG00000162729 ENSG00000288210 ENSG00000138378 ENSG00000163171 ENSG00000180957 ENSG00000197299 ENSG00000186432 ENSG00000051825 ENSG00000133657 ENSG00000127838 PMC7827855__F1 Interplay between the Hippo, Wnt and ARF/p53 signaling pathways in development and tumorigenesis ENSG00000149311 ENSG00000134982 ENSG00000150457 ENSG00000131023 PMC3410580__F6 p62/SQSTM1 acts either as a pro-oncogene or as a tumor suppressor protein ENSG00000134982 ENSG00000198793 ENSG00000168036 ENSG00000083799 ENSG00000175104 PMC3410580__F2 Structure and interacting partners of p62/SQSTM1 ENSG00000188554 ENSG00000198793 ENSG00000175104 ENSG00000079999 PMC4943213__F1 Wnt signaling ENSG00000134982 ENSG00000168036 PMC9599635__F1 Pathogenesis of Huntington’s Disease: An Emphasis on Molecular Pathways and Prevention by Natural Remedies PMC3363966__F4 Components and targets of pro-phenol oxidase, Toll-Dorsal/Dif and JAK/STAT pathways ENSG00000291791 ENSG00000172936 ENSG00000127191 PMC3058199__F6 Noonan syndrome and clinically related disorders ENSG00000157764 ENSG00000110395 ENSG00000115904 ENSG00000166068 ENSG00000108061 ENSG00000062485 PMC9599635__F2 Pathogenesis of Huntington’s Disease: An Emphasis on Molecular Pathways and Prevention by Natural Remedies ENSG00000084093 ENSG00000169375 PMC5859860__F2 Proposed model of cross-regulation between LAP and canonical autophagy in p47phox−/− mice ENSG00000039537 PMC6739980__F3 Summary of ventral midline crossing ENSG00000144857 ENSG00000164690 ENSG00000154134 PMC9026123__F1 Cytotoxicity of Thiopurine Drugs in Patients with Inflammatory Bowel Disease ENSG00000137364 ENSG00000136159 PMC5398309__F2 Visible model is an excerpt of the KEGG (Kyoto Encyclopedia of Genes and Genomes) FoxO signaling pathway in humans as appears after importing in bStyle ENSG00000145604 ENSG00000087095 ENSG00000171105 ENSG00000126457 ENSG00000123374 ENSG00000168610 ENSG00000140443 PMC3078187__F1 Signaling Cell Death from the Endoplasmic Reticulum Stress Response ENSG00000128272 ENSG00000144895 PMC7724774__F1 PD-L1 expression through NFKB ENSG00000146648 PMC2894370__F4 “Where, O Death, Is Thy Sting?” A Brief Review of Apoptosis Biology ENSG00000134086 ENSG00000198793 PMC6399501__F3 Disorders resulting from mutational defects in the lysosomal SL degradation pathway ENSG00000170266 ENSG00000197746 ENSG00000213614 ENSG00000196743 ENSG00000049860 PMC2825767__F2 Adrenal cholesterol biosynthesis pathway gene expression is globally underexpressed in the Chga knockout mouse ENSG00000160752 ENSG00000067064 ENSG00000110921 ENSG00000172893 ENSG00000109929 ENSG00000113161 ENSG00000104549 ENSG00000167508 PMC2825767__F1 Adrenal insulin signaling and glucose transport gene expression is overexpressed in the chromogranin A (Chga) knockout mouse ENSG00000104812 ENSG00000140992 ENSG00000065675 ENSG00000136111 ENSG00000108443 ENSG00000100485 ENSG00000173327 ENSG00000175634 ENSG00000163558 ENSG00000148082 ENSG00000167941 ENSG00000150907 ENSG00000106070 ENSG00000220205 ENSG00000100219 ENSG00000196455 ENSG00000065559 ENSG00000132639 ENSG00000104814 ENSG00000110395 ENSG00000133124 ENSG00000079435 ENSG00000130758 ENSG00000288174 ENSG00000136854 ENSG00000095015 ENSG00000141639 ENSG00000168067 ENSG00000197442 ENSG00000142733 ENSG00000105647 ENSG00000166484 ENSG00000069956 ENSG00000139625 ENSG00000135341 ENSG00000121879 ENSG00000196396 ENSG00000137764 ENSG00000116266 ENSG00000115290 ENSG00000166592 ENSG00000168118 ENSG00000179295 ENSG00000169967 ENSG00000073803 ENSG00000166263 ENSG00000011566 ENSG00000101049 ENSG00000141503 ENSG00000143761 ENSG00000129946 ENSG00000165458 ENSG00000197594 ENSG00000024422 ENSG00000027075 ENSG00000171105 ENSG00000104365 ENSG00000111713 ENSG00000006062 ENSG00000160999 ENSG00000186298 ENSG00000101255 ENSG00000067606 ENSG00000162409 ENSG00000177606 ENSG00000163754 PMC5953777__F3 Cancer-relevant signaling pathways ENSG00000002330 ENSG00000067900 ENSG00000084774 PMC2825767__F3 Hepatic cholesterol biosynthesis pathway gene expression is globally overexpressed in the Chga knockout mouse ENSG00000160752 ENSG00000110921 ENSG00000172893 ENSG00000109929 ENSG00000113161 ENSG00000104549 ENSG00000167508 PMC9652939__F9 MICAL1 facilitates pancreatic cancer proliferation, migration, and invasion by activating WNT/Beta-catenin pathway ENSG00000134982 ENSG00000168036 ENSG00000155760 ENSG00000135596 PMC5953777__F2 Connectivity of differentially expressed genes in the important cancer signaling pathways in the exposed children are shown according to gene expression levels (with ≥ 1.5-fold change, t test, p < 0.05) ENSG00000077150 ENSG00000136997 PMC10995750__F3 Genes enriched in plasma membrane estrogen receptor signalling pathway ENSG00000112576 ENSG00000159216 ENSG00000084676 ENSG00000115415 ENSG00000177606 ENSG00000101266 ENSG00000139687 ENSG00000127616 ENSG00000196367 PMC3599951__F5 Phytochemicals targeting NFkB signaling pathway ENSG00000002330 PMC10540768__F2 Unleashing the power of complement activation: unraveling renal damage in human anti-glomerular basement membrane disease ENSG00000039537 ENSG00000009724 ENSG00000113600 ENSG00000291559 ENSG00000288512 ENSG00000244731 ENSG00000166278 ENSG00000182326 PMC4027049__F2 TGFB signalling in context ENSG00000163914 ENSG00000175104 ENSG00000204217 ENSG00000113360 PMC5466034__F10 A Putative Model of Central Carbon and Energy Metabolism in Tomato GTs.A type VI glandular cell with its plasma membrane as a black line ENSG00000039537 ENSG00000122966 ENSG00000172005 ENSG00000197429 PMC9367255__F2 Autophagy-Associated Immunogenic Modulation and Its Applications in Cancer Therapy ENSG00000144848 ENSG00000175104 ENSG00000057663 PMC8690896__F1 E-cadherin on epithelial–mesenchymal transition in thyroid cancer ENSG00000107562 ENSG00000157764 ENSG00000197635 ENSG00000198793 ENSG00000146648 ENSG00000121966 PMC2749270__F1 Sphingosine-1-phosphate synthesis and functions in mast cells ENSG00000063176 ENSG00000010810 PMC3261582__F1 JNK signaling enhances the compensatory proliferation of the neighboring cells, stem cells or cancer stem cells (CSCs) ENSG00000136997 ENSG00000026508 ENSG00000136826 PMC6399501__F2 Mechanisms of pathogenesis of inborn errors of SL metabolism ENSG00000100596 ENSG00000154227 ENSG00000166224 ENSG00000119537 ENSG00000049860 ENSG00000148154 PMC6399501__F1 Disorders resulting from mutational defects in the SL synthesis pathway for ceramide and GSLs and the nonlysosomal SL degradation pathway ENSG00000223802 ENSG00000100596 ENSG00000154227 ENSG00000135454 ENSG00000166224 ENSG00000172057 ENSG00000119537 ENSG00000115525 ENSG00000078124 ENSG00000148154 PMC12055549__F0 Proposed signaling pathway of tetramethylpyrazine (TMPZ) in protecting against acute pancreatitis through inhibition of pyroptosis via the NRF2 pathway ENSG00000278718 ENSG00000162711 PMC7906182__F4 Interacting networks between coiled-coil domain-containing protein 167 (CCDC167) and micro (mi)RNA ENSG00000087245 ENSG00000008710 ENSG00000128272 ENSG00000183691 ENSG00000185591 ENSG00000100985 ENSG00000104332 ENSG00000105996 ENSG00000123908 ENSG00000140443 PMC3012182__F1 TRPM channels in insulin secretion ENSG00000070985 PMC7906182__F3 MetaCore pathway analysis of coiled-coil domain-containing protein 167 (CCDC167)-co-expressed genes in breast cancer patient databases ENSG00000145604 ENSG00000068028 ENSG00000134982 ENSG00000123374 ENSG00000120438 ENSG00000166851 ENSG00000117399 ENSG00000062485 PMC8624906__F2 Transcriptional Regulation of Ripening in Chili Pepper Fruits (Capsicum spp.) ENSG00000173992 PMC199181__F2 Proposed mechanisms of NFKB activation in HIV-1–infected cells ENSG00000168040 ENSG00000127191 PMC7772706__F3A Based on network pharmacology method to discovered the targets and therapeutic mechanism of Paederia scandens against nonalcoholic fatty liver disease in chicken ENSG00000162711 ENSG00000157933 ENSG00000102871 ENSG00000168040 ENSG00000150455 ENSG00000274145 ENSG00000276068 ENSG00000136997 ENSG00000198517 ENSG00000006451 ENSG00000125538 ENSG00000185591 ENSG00000175104 ENSG00000167182 PMC199181__F3 The NFKB pathway by viruses ENSG00000102871 ENSG00000127191 PMC4425424__F3 Transcriptional regulation of cranial sensory placode development ENSG00000152977 ENSG00000163132 PMC6124012__F6 Sterol regulatory element-binding protein 1 signaling ENSG00000130164 ENSG00000172893 ENSG00000169710 PMC11414398__F7 Alternative Src regulatory pathway mediated by the METTL18-RPL3-HSP90-actin axis in HER2-negative breast cancers ENSG00000291971 ENSG00000171806 PMC6406790__F1 The schematic diagram represents the treatment schedule and the mechanism of NAM neuroprotection in mouse brains ENSG00000125538 ENSG00000171791 ENSG00000164305 PMC11023816__F9 Proposed pathways by which paracrine and autocrine cytokine signaling modulates vitamin A metabolism across stellate cell activation phenotypes ENSG00000121207 ENSG00000138207 ENSG00000143320 ENSG00000172936 ENSG00000136869 ENSG00000127191 PMC8771518__F7 Ophiopogonin B alleviates cisplatin resistance of lung cancer cells by inducing Caspase-1/GSDMD dependent pyroptosis ENSG00000278718 ENSG00000162711 ENSG00000125538 PMC7415260__F4 Signaling pathway visualization based on changed protein and transcript expression of SYN1, SYN2, SYN3, SNAP25, STX1A, RAB3A, and STMN1 in recurrent samples ENSG00000220205 ENSG00000132639 ENSG00000008056 PMC3544784__F1 Insight into the role of CRMP2 (collapsin response mediator protein 2) in T lymphocyte migration ENSG00000107562 ENSG00000121966 PMC2387183__F4 Autocrine/paracrine induction of osteogenesis in hMSCs by PKA signaling ENSG00000137834 ENSG00000125740 ENSG00000172201 PMC9424640__F7 Therapeutic potential of NR4A1 in cancer: Focus on metabolism ENSG00000178860 ENSG00000174059 PMC11786761__F9 SH2B1 promotes apoptosis in diabetic cataract via p38 MAPK pathway ENSG00000178188 ENSG00000171791 PMC5453624__F5 Comparison of the adolescent and adult mouse prefrontal cortex proteome ENSG00000011304 ENSG00000102606 ENSG00000242689 ENSG00000140740 ENSG00000198793 ENSG00000136854 ENSG00000164327 ENSG00000145920 ENSG00000275544 ENSG00000225950 ENSG00000099904 PMC3791178__F1 The Autophagy Pathway by Human Tumor Viruses ENSG00000198793 ENSG00000144848 ENSG00000145782 ENSG00000057663 PMC11023816__F1 Vitamin A metabolic pathway and the enzymes involved in retinoid metabolic flux in human liver ENSG00000095596 ENSG00000121207 ENSG00000138207 ENSG00000003137 ENSG00000121039 ENSG00000128918 ENSG00000100344 ENSG00000143320 PMC5453624__F7 Comparison of the adolescent and adult mouse prefrontal cortex proteome ENSG00000142192 ENSG00000102081 ENSG00000197971 ENSG00000010017 ENSG00000122705 ENSG00000145920 ENSG00000007171 ENSG00000132170 PMC8939123__F1 Sirtuin family members in chronic obstructive pulmonary disease ENSG00000162711 ENSG00000187531 ENSG00000096088 ENSG00000168036 ENSG00000077463 ENSG00000089163 ENSG00000168610 ENSG00000283100 PMC4163877__F2 Integrated signaling networks and tumor cellular bioenergetics ENSG00000127837 ENSG00000198793 PMC11985700__F1 Key signalling pathways involved in muscle atrophy and hypertrophy ENSG00000084093 ENSG00000198793 PMC3988951__F6 Insights into TREM2-related signaling using data-driven network constructions and information provided by Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis ENSG00000213658 ENSG00000183864 ENSG00000165527 PMC7139637__F4 YAP drug targets ENSG00000141867 ENSG00000291971 ENSG00000150457 ENSG00000131023 PMC4433473__F4 Surface Fzd density by R-spondin-LGR5-RNF43 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000183579 ENSG00000168036 ENSG00000108375 ENSG00000196628 PMC8877508__F1 Relevance of TLR8 in Viral Infections ENSG00000172936 ENSG00000175104 ENSG00000276561 PMC7139637__F3 Crosstalk between YAP signaling pathway and both TEAD and TGFB pathways ENSG00000136535 ENSG00000150457 ENSG00000131023 PMC4433473__F3 Ligand-dependent LRP6 endocytosis ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000196628 PMC7218640__F1 CRNDE significantly promotes cell proliferation through mediating multiple signaling pathways and various target genes ENSG00000176842 ENSG00000275385 ENSG00000112242 ENSG00000198793 ENSG00000168036 ENSG00000214753 ENSG00000168610 ENSG00000196628 PMC4759558__F12 CMKLR1 deficiency maintains ovarian steroid production in mice treated chronically with dihydrotestosterone ENSG00000174600 PMC7139637__F1 Hippo/yes-associated protein (YAP) signaling pathway in mammals ENSG00000186575 ENSG00000089685 ENSG00000150457 ENSG00000131023 PMC8197279__F2 Damage-Associated Molecular Patterns Modulation by microRNA: Relevance on Immunogenic Cell Death and Cancer Treatment Outcome ENSG00000189403 PMC3049335__F1 The Nrf2 pathway in PD pathogenesis ENSG00000181019 ENSG00000178573 ENSG00000105227 ENSG00000079999 PMC6356367__F3 Upstream factors of the TOR pathway ENSG00000138798 ENSG00000146648 PMC5525309__F1 Innate immunity ENSG00000174125 ENSG00000239732 ENSG00000134982 ENSG00000136869 ENSG00000164342 PMC6549764__F3 15d-PGJ2 regulates adipocyte differentiation and osteoblast differentiation via a PPARGamma-dependent pathway ENSG00000178860 ENSG00000168036 PMC8194229__F3 Novel method to identify gene interaction patterns ENSG00000136546 ENSG00000130294 ENSG00000122218 ENSG00000109113 ENSG00000101350 ENSG00000075945 ENSG00000168818 ENSG00000134287 ENSG00000105402 ENSG00000105669 ENSG00000148396 ENSG00000154917 ENSG00000121542 ENSG00000107862 ENSG00000114745 ENSG00000176986 ENSG00000143952 ENSG00000136883 ENSG00000173898 ENSG00000128510 ENSG00000080166 ENSG00000163554 ENSG00000054523 PMC7395429__F7 Proposed model for MBP-induced abnormal cell growth of juvenile SCs ENSG00000197971 ENSG00000184216 PMC7663205__F2 Role of PITPNM3 in cancer cell migration ENSG00000275385 ENSG00000198793 ENSG00000162692 PMC7894993__F2 Extrinsic and intrinsic factors that regulate self-renewal in embryonic and adult haematopoiesis ENSG00000169896 ENSG00000128272 ENSG00000164736 ENSG00000162676 ENSG00000117400 ENSG00000108799 ENSG00000187772 ENSG00000166068 PMC6496801__F4 The primary molecular pathways leading to pyroptosis in monocytes/macrophages in CVDs ENSG00000278718 ENSG00000162711 ENSG00000135218 PMC11043957__F2 Nrf-2 and signaling pathways ENSG00000181019 PMC11043957__F1 Signaling pathways in radiation-induced lung injury ENSG00000163453 PMC6496801__F2 Multiple pathways that mediate pyroptosis ENSG00000278718 ENSG00000162711 ENSG00000185515 ENSG00000213928 ENSG00000163568 ENSG00000265972 ENSG00000168040 ENSG00000276561 ENSG00000105397 ENSG00000142405 ENSG00000136869 ENSG00000172936 ENSG00000175104 PMC6496801__F1 Caspase‐1–dependent and independent pyroptotic pathway ENSG00000278718 ENSG00000162711 ENSG00000163568 ENSG00000163914 PMC10875826__F1 (i) ERBB/HER family members and their cognate ligands (ii) Structural difference of various (I-VI) types of NRG1 ENSG00000113070 ENSG00000138798 ENSG00000158458 ENSG00000169752 PMC8305013__F1 Behind the Scene: Exploiting MC1R in Skin Cancer Risk and Prevention ENSG00000157404 ENSG00000080166 PMC7550420__F2 Process and regulation of STING trafficking ENSG00000183735 ENSG00000100330 ENSG00000108389 ENSG00000106266 ENSG00000198925 ENSG00000145817 PMC7550420__F1 Diagram of STING-mediated immune response to viruses ENSG00000183735 ENSG00000164430 PMC100005__F11 Formation of TrkA–src-aPKC complexes ENSG00000291971 ENSG00000175104 PMC7185083__F5 PTEN may regulate autophagy by allowing for a bypass of PTEN/PRAS40 signaling in TSC2-/- cells and influence cell proliferation PMC7559772__F2 Genetic regulation of cell fate and size of the progenitor zone ENSG00000129167 ENSG00000123374 PMC6386770__F1 Differences in the functional impact of IL-7/IL-7R-mediated signaling in T-ALL cells and their normal counterparts ENSG00000198793 ENSG00000105639 PMC5525309__F6 Working model of metabolic risk factor-induced two-way stimulatory immune checkpoint amplification and systemic/tissue inflammation ENSG00000134982 ENSG00000168610 PMC8113818__F2 Unfolded protein response (UPR), autophagy and coronavirus (CoV) infections ENSG00000126775 ENSG00000057663 PMC8511434__F4 Type 3 Innate Lymphoid Cells as Regulators of the Host-Pathogen Interaction ENSG00000148346 ENSG00000162711 ENSG00000138378 ENSG00000020633 ENSG00000168610 PMC5951756__F4 Insulin/IGF-1 signalling map ENSG00000131473 ENSG00000171105 ENSG00000033327 ENSG00000002330 ENSG00000070831 ENSG00000198793 ENSG00000169047 ENSG00000115904 ENSG00000108443 ENSG00000160999 ENSG00000184481 ENSG00000160691 ENSG00000117020 ENSG00000107263 ENSG00000110395 ENSG00000182473 ENSG00000150907 ENSG00000133124 ENSG00000112186 ENSG00000105723 ENSG00000140443 PMC8511434__F6 Type 3 Innate Lymphoid Cells as Regulators of the Host-Pathogen Interaction ENSG00000205221 ENSG00000146469 ENSG00000125538 ENSG00000198793 ENSG00000168610 ENSG00000112486 PMC4715089__F1 TGFB/Smads and crosstalk pathways in renal fibrosis and inflammation ENSG00000125538 PMC4192457__F2 Signaling pathway regulation of autophagy by several factors ENSG00000177169 ENSG00000198382 ENSG00000126775 ENSG00000198793 PMC3562679__F1 Lipopolysaccharide (endotoxin) signaling pathway ENSG00000170458 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC3527539__F7 Up-regulated miR155 Reverses the Epithelial-mesenchymal Transition Induced by EGF and Increases Chemo-sensitivity to Cisplatin in Human Caski Cervical Cancer Cells ENSG00000138798 ENSG00000168036 ENSG00000146648 ENSG00000196628 PMC3709966__F4 HIV-1 Vpr Modulates Macrophage Metabolic Pathways: A SILAC-Based Quantitative Analysis ENSG00000109061 ENSG00000163914 ENSG00000165283 ENSG00000129351 ENSG00000291420 PMC8650317__F1 Mitochondrial Dysfunction in Advanced Liver Disease: Emerging Concepts ENSG00000106546 PMC3906243__F6 Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets ENSG00000228716 ENSG00000016391 PMC10245950__F9 ß-oxidation pathway for fatty acids is strongly downregulated by oxaliplatin ENSG00000157184 ENSG00000039537 ENSG00000151726 ENSG00000138029 ENSG00000105953 ENSG00000075239 ENSG00000127884 PMC4816150__F2 Adiponectin signal transduction pathway implicating a crosstalk with the insulin signaling pathway ENSG00000157500 ENSG00000169047 ENSG00000198793 PMC7970116__F3 Genomic characteristics of ccRCC for manipulating the TIME ENSG00000169245 ENSG00000134086 ENSG00000108691 ENSG00000101751 ENSG00000111537 ENSG00000118520 PMC11787754__F8 EA treatment might activate the mitophagy-related PINK1/Parkin signaling pathway through lncRNA-XR_002789763 ENSG00000123240 ENSG00000175193 ENSG00000116688 ENSG00000158828 PMC7970116__F2 Bidirectional Relationship between targeted therapies (VEGF/VEGFR inhibitors) and TIME in ccRCC ENSG00000108691 ENSG00000107562 ENSG00000121807 ENSG00000121966 PMC5977762__F2 Up-regulation of the JAK-STAT and mTOR pathways: Ingenuity pathway maps for a JAK-STAT signaling (transducing extracellular signals to transcriptional responses) and b mTOR signaling (a master regulator for many fundamental cellular repair processes) ENSG00000173599 ENSG00000143839 ENSG00000113520 PMC7970116__F1 Mechanisms influencing immunotherapy response in the TIME in ccRCC ENSG00000089692 ENSG00000196839 ENSG00000118520 PMC4102648__F2 UV signaling pathways within the skin ENSG00000107165 ENSG00000113448 PMC11787754__F1 PINK1-dependent mitophagy ENSG00000123240 ENSG00000175193 ENSG00000116688 ENSG00000158828 PMC9385636__F7 Salidroside alleviates hepatic ischemia–reperfusion injury during liver transplant in rat through regulating TLR-4/NFKB/NLRP3 inflammatory pathway ENSG00000162711 ENSG00000125538 ENSG00000172936 PMC9406578__F2 Targeting Heat-Shock Protein 90 in Cancer: An Update on Combination Therapy ENSG00000149311 ENSG00000168610 PMC6482176__F1 The Insulin Signalling Pathway and insulin resistance ENSG00000169047 ENSG00000084733 PMC9043866__F8 TAZ ameliorates the microglia-mediated inflammatory response via the Nrf2-ROS-NFKB pathway ENSG00000125538 ENSG00000164305 PMC3251736__F2 Ingenuity pathway analysis (IPA) of the EGFR ablation signature with oncogenic (A) and wildtype Ras (B) ENSG00000100234 ENSG00000288269 ENSG00000140795 ENSG00000163739 ENSG00000203710 ENSG00000163083 ENSG00000197969 ENSG00000173905 ENSG00000138160 ENSG00000132671 ENSG00000087128 ENSG00000094804 ENSG00000112116 ENSG00000148702 ENSG00000117335 ENSG00000167182 ENSG00000162896 PMC7729585__F2 Fatty acid metabolism, glycolysis, and tricarboxylic acid cycle (TCA) cycle ENSG00000157184 ENSG00000143252 ENSG00000131238 ENSG00000067992 ENSG00000005882 ENSG00000100294 ENSG00000082212 ENSG00000136872 ENSG00000281500 PMC4858538__F4 Role of p38 MAPK in Wnt signaling ENSG00000107404 ENSG00000281324 ENSG00000162337 ENSG00000168036 ENSG00000196628 PMC9109300__F7 Silencing of histone deacetylase 3 suppresses the development of esophageal squamous cell carcinoma through regulation of miR-494-mediated TGIF1 ENSG00000171720 PMC5329966__F3 Heterogeneous responses of normal and malignant B cells upon CpG ODNs stimulation ENSG00000239732 ENSG00000115415 ENSG00000172936 ENSG00000175104 ENSG00000184216 ENSG00000026103 PMC10143138__F2 Osteoblast cellular cholesterol homeostasis ENSG00000130164 ENSG00000042832 ENSG00000113161 PMC6917641__F1 Drugs with clinical potential in cancer that modulate miRNAs implicated in cell metabolism ENSG00000169554 ENSG00000169047 ENSG00000198793 ENSG00000185591 ENSG00000126778 ENSG00000159399 PMC9563854__F3 Natural antisense transcripts as drug targets ENSG00000101557 PMC10253382__F3 Anti-inflammatory pathways induced by baicalin ENSG00000162711 ENSG00000150907 ENSG00000189403 ENSG00000136869 PMC8841999__F1 ER Disposal Pathways in Chronic Liver Disease: Protective, Pathogenic, and Potential Therapeutic Targets ENSG00000008952 ENSG00000130649 ENSG00000164081 ENSG00000184743 ENSG00000260916 ENSG00000118640 ENSG00000136874 PMC5748990__F2 Pathways regulating senescence-mediated arrest ENSG00000135446 ENSG00000105810 PMC4403295__F2 ER-mitochondrion tethering ENSG00000162711 ENSG00000116688 ENSG00000140464 ENSG00000171109 ENSG00000214253 PMC8207264__F6 Metabolism-Based Gene Differences in Neurons Expressing Hyperphosphorylated AT8− Positive (AT8+) Tau in Alzheimer’s Disease ENSG00000122966 ENSG00000124275 ENSG00000036473 PMC4403295__F1 The UPR signaling pathway ENSG00000128272 ENSG00000100219 PMC9029304__F1 Metformin in Differentiated Thyroid Cancer: Molecular Pathways and Its Clinical Implications ENSG00000169047 ENSG00000198793 PMC6169995__F3 Differential targeting of genes in the drug metabolism pathway ENSG00000170899 ENSG00000184254 ENSG00000108242 ENSG00000248144 ENSG00000197408 ENSG00000100577 ENSG00000008394 ENSG00000143198 ENSG00000138356 ENSG00000006534 ENSG00000076258 ENSG00000132746 ENSG00000085871 ENSG00000277897 ENSG00000196620 ENSG00000185129 ENSG00000168765 PMC8875462__F4 Osteocrin, a bone-derived humoral factor, exerts a renoprotective role in ischemia–reperfusion injury in mice ENSG00000087095 ENSG00000137673 ENSG00000095739 ENSG00000100387 ENSG00000134982 ENSG00000147869 ENSG00000167941 ENSG00000133067 ENSG00000113558 ENSG00000100211 ENSG00000196470 ENSG00000185269 PMC6277637__F3 Main brain-immune system pathways and feedback loops illustrating the interconnected effects of physical and emotional stress in health ENSG00000170893 ENSG00000166278 ENSG00000132693 PMC9136512__F10 CDK5RAP3, an essential regulator of checkpoint, interacts with RPL26 and maintains the stability of cell growth ENSG00000198793 ENSG00000161970 ENSG00000108465 ENSG00000149554 ENSG00000183765 PMC4772904__F1 NSAIDs inhibit PGE2-induced tumorigenesis through targeting multiple downstream signaling pathways of PGE2 ENSG00000168036 ENSG00000146648 PMC8353915__F6 VLX1570 induces apoptosis through the generation of ROS and induction of ER stress on leukemia cell lines ENSG00000128272 ENSG00000144895 ENSG00000196839 ENSG00000100219 ENSG00000101557 PMC3495983__F6 Model illustrating CD40-induced signals that mediate the expression of VEGF in endothelial cells ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC4786283__F2 Stability of Ensemble Models Predicts Productivity of Enzymatic Systems ENSG00000197713 ENSG00000163064 ENSG00000112742 PMC8310438__F1 Corrigendum to “Expression and Gene Regulation Network of Metabolic Enzyme Phosphoglycerate Mutase Enzyme 1 in Breast Cancer Based on Data Mining” ENSG00000067057 ENSG00000161203 ENSG00000226784 ENSG00000213341 ENSG00000078237 ENSG00000164708 ENSG00000137509 PMC11465581__F8 The effect of neuroinvasion on immune tolerance in NSCLC NGF released from NSCLC cells induces neuronal cell differentiation and axonogenesis in the tumor microenvironment (TME) ENSG00000198793 ENSG00000179546 PMC9611604__F7 How does Quorum Sensing of Intestinal Bacteria Affect Our Health and Mental Status? ENSG00000111537 ENSG00000168036 ENSG00000140465 ENSG00000106546 PMC5608833__F10 Rep-MYB-mediated repression of G2/M-specific genes under DNA stress conditions ENSG00000149311 ENSG00000175054 PMC3942330__F6 Small GTPases of the Ras superfamily regulate intestinal epithelial homeostasis and barrier function via common and unique mechanisms ENSG00000125249 ENSG00000123728 ENSG00000141068 ENSG00000154310 ENSG00000154928 PMC3942330__F5 Small GTPases of the Ras superfamily regulate intestinal epithelial homeostasis and barrier function via common and unique mechanisms ENSG00000070831 ENSG00000291971 ENSG00000198087 ENSG00000160293 ENSG00000146648 PMC3000836__F1 Comparison of the DC-ATLAS Toll Like Receptor (TLR) 3 pathway with other pathway databases ENSG00000165983 ENSG00000170458 ENSG00000158825 ENSG00000100842 ENSG00000150455 PMC3942330__F4 Small GTPases of the Ras superfamily regulate intestinal epithelial homeostasis and barrier function via common and unique mechanisms ENSG00000132906 ENSG00000291971 ENSG00000138798 ENSG00000146648 ENSG00000164305 PMC6281690__F4 Schematic illustration representing metabolic and transport proteins hypothesized from the genome of Ca ENSG00000148798 ENSG00000038002 PMC3519537__F5 Using Answer Set Programming to Integrate RNA Expression with Signalling Pathway Information to Infer How Mutations Affect Ageing ENSG00000284161 ENSG00000164327 ENSG00000166278 PMC3942330__F3 Small GTPases of the Ras superfamily regulate intestinal epithelial homeostasis and barrier function via common and unique mechanisms ENSG00000132694 ENSG00000107562 ENSG00000067900 ENSG00000164305 ENSG00000121966 PMC6305103__F2 Tumor metabolism regulating chemosensitivity in ovarian cancer ENSG00000157764 ENSG00000136997 ENSG00000198670 ENSG00000078237 PMC6823874__F1 Pan-Cancer Analysis of Potential Synthetic Lethal Drug Targets Specific to Alterations in DNA Damage Response ENSG00000101751 ENSG00000177084 ENSG00000127948 PMC10309183__F4 Ether lipids and a peroxisomal riddle in sperm ENSG00000018510 ENSG00000158669 ENSG00000116906 ENSG00000109016 ENSG00000186281 ENSG00000197601 PMC11393989__F1 Molecular and cellular mechanisms of TGFB signaling pathway in GO ENSG00000107404 ENSG00000281324 ENSG00000125398 ENSG00000162337 ENSG00000086991 ENSG00000174804 PMC3942330__F8 Small GTPases of the Ras superfamily regulate intestinal epithelial homeostasis and barrier function via common and unique mechanisms ENSG00000107862 ENSG00000143761 ENSG00000291971 ENSG00000165527 PMC6920345__F3 The impact of oncogenic RAS on redox balance and implications for cancer development ENSG00000128272 ENSG00000177606 ENSG00000136997 ENSG00000172005 ENSG00000123983 PMC3855668__F1 Model of the signaling pathway mediated by ATM in response to DSBs induced by IR, as proposed by Kitagawa et al ENSG00000188486 ENSG00000149311 ENSG00000012048 PMC3519537__F1 Using Answer Set Programming to Integrate RNA Expression with Signalling Pathway Information to Infer How Mutations Affect Ageing ENSG00000147044 ENSG00000136997 ENSG00000284161 ENSG00000164327 ENSG00000166278 ENSG00000038002 ENSG00000151914 ENSG00000172795 PMC11826106__F9 CSRP2 inhibits the necroptosis of glioma cells by activating the JAK-STAT1 signaling pathway ENSG00000137275 ENSG00000115415 ENSG00000175183 ENSG00000033800 ENSG00000168404 ENSG00000285379 PMC4371597__F1 Evaluation of the Unfolded Protein Response: PI 3-Kinase Regulatory Subunits as Regulators of the IRE1A Pathway ENSG00000128272 ENSG00000144895 PMC8043893__F9 SKI activates the Hippo pathway via LIMD1 to inhibit cardiac fibroblast activation ENSG00000157933 ENSG00000159753 ENSG00000150457 ENSG00000144791 PMC3123739__F8 DNA Repair Deficiency in Neurodegeneration ENSG00000149311 ENSG00000105486 ENSG00000165392 ENSG00000197299 ENSG00000051180 ENSG00000042088 ENSG00000112130 PMC4417967__F2 Relative adenine and thymine (%AT) DNA content of ergot alkaloid synthesis (EAS) loci ENSG00000081051 ENSG00000088926 ENSG00000093009 PMC7521342__F5 Global gene expression analyses of the alkamide-producing plant Heliopsis longipes supports a polyketide synthase-mediated biosynthesis pathway ENSG00000155966 ENSG00000072364 PMC5260500__F3 DAB2IP in TNFA signaling: activation of ASK1/JNK ENSG00000102871 ENSG00000136848 ENSG00000127191 PMC8061373__F1 Schematic hypothesis of the proposed mechanisms of TLR3 derived from SARS-CoV-2 leading to hypertension ENSG00000183735 ENSG00000023734 ENSG00000130234 ENSG00000164342 PMC7062180__F1 A, the mammalian polyamine metabolic pathway ENSG00000088826 ENSG00000148832 ENSG00000116649 ENSG00000102172 PMC9592233__F5 Lipid Profiling of Pacific Abalone (Haliotis discus hannai) at Different Developmental Stages Using Ultrahigh Performance Liquid Chromatography-Tandem Mass Spectrometry ENSG00000042832 ENSG00000173599 ENSG00000198670 PMC2798676__F10 Genetic and epigenetic silencing of SCARA5 may contribute to human hepatocellular carcinoma by activating FAK signaling ENSG00000168079 ENSG00000070831 ENSG00000291971 ENSG00000163914 ENSG00000100985 PMC1829400__F5 TGFB signaling pathway ENSG00000183691 ENSG00000136997 PMC12072309__F1 Schematic illustration depicting the dysregulation of the NF2/Merlin-Hippo signaling cascade in mesothelioma cells ENSG00000129474 ENSG00000150457 ENSG00000131023 PMC4581967__F1 Evasion and Interactions of the Humoral Innate Immune Response in Pathogen Invasion, Autoimmune Disease, and Cancer ENSG00000039537 ENSG00000291559 ENSG00000244731 ENSG00000062485 PMC8452443__F3 Follicular Helper CD4+ T Cells, Follicular Regulatory CD4+ T Cells, and Inducible Costimulator and Their Roles in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis ENSG00000134982 ENSG00000150907 ENSG00000127528 ENSG00000126353 PMC8391678__F2 LIM-Kinases in Synaptic Plasticity, Memory, and Brain Diseases ENSG00000106683 ENSG00000169750 ENSG00000149269 ENSG00000163914 PMC10955039__F6 Hippo signalling pathway in ferroptosis ENSG00000167772 ENSG00000151012 ENSG00000167468 ENSG00000086991 ENSG00000134531 PMC2649808__F5 Comparative Proteomic Phenotyping of Cell Lines and Primary Cells to Assess Preservation of Cell Type-specific Functions ENSG00000110395 ENSG00000198793 ENSG00000026103 ENSG00000047932 PMC3387654__F1 Mammalian Hippo pathway and cancer ENSG00000186575 ENSG00000150457 ENSG00000131023 PMC7965781__F1 Control of the insect metamorphic transition by ecdysteroid production and secretion ENSG00000039537 ENSG00000105251 PMC6966089__F2 Methanol condensation cycle (MCC) for assimilation of methanol into higher alcohol with maximal carbon conservation ENSG00000197713 ENSG00000171444 PMC8354137__F1 Exploring the contribution of the mitochondrial disulfide relay system to Parkinson’s disease: the PINK1/CHCHD4 interplay ENSG00000175193 ENSG00000158828 ENSG00000163528 PMC3807098__F1 Squalene Synthase Inhibitor Lapaquistat Acetate: Could Anything Be Better Than Statins? ENSG00000070831 PMC4166715__F4 mTOR transcriptional activity ENSG00000140992 ENSG00000157764 ENSG00000162409 ENSG00000198793 ENSG00000169047 ENSG00000155876 ENSG00000164327 ENSG00000025039 ENSG00000140443 ENSG00000083750 PMC2151969__F4 Genes up-regulated and down-regulated by FGF-2 in IGF-I signaling pathway ENSG00000164151 ENSG00000075891 ENSG00000140443 PMC2151969__F5 Genes up-regulated and down-regulated by FGF-2 in TGFB signaling pathway ENSG00000160973 ENSG00000037965 ENSG00000133937 ENSG00000115297 ENSG00000177606 ENSG00000156574 ENSG00000164093 PMC4905175__F1 Telomere uncapping at the crossroad between cell cycle arrest and carcinogenesis ENSG00000149311 ENSG00000080345 ENSG00000128513 PMC7227208__F6 TGF-beta signaling pathway enriched in KEGG ENSG00000067141 ENSG00000111537 ENSG00000095739 ENSG00000187720 ENSG00000100387 ENSG00000113558 ENSG00000156574 ENSG00000134363 ENSG00000185591 ENSG00000205250 ENSG00000166147 ENSG00000137801 PMC5412951__F1 Glucocorticoids Inhibit Wound Healing: Novel Mechanism of Action ENSG00000145321 ENSG00000168036 PMC9601711__F1 Hereditary Metabolic Bone Diseases: A Review of Pathogenesis, Diagnosis and Management ENSG00000118972 ENSG00000105516 ENSG00000015285 ENSG00000092199 ENSG00000186104 PMC2556276__F1 Display of differentially expressed genes in the uterine cervix after term spontaneous labor mapped on the PLAU signaling pathway ENSG00000019991 ENSG00000011422 ENSG00000115415 ENSG00000291971 ENSG00000146648 ENSG00000122194 ENSG00000104368 ENSG00000135919 PMC8660968__F1 Regulatory Mechanism of 2-Acetyl-1-Pyrroline Biosynthesis in Fragrant Rice (Oryza sativa L.) Under Different Soil Moisture Contents ENSG00000100033 PMC12210776__F4 Key mechanism diagram of the combination of JZOL and AZ in the treatment of MPP ENSG00000149968 ENSG00000157227 ENSG00000163739 ENSG00000007908 ENSG00000073756 ENSG00000115009 PMC8023395__F2 Towards personalized treatment for early stage HER2-positive breast cancer ENSG00000291971 ENSG00000198793 PMC6141803__F2 Indoximod mechanisms of action ENSG00000188676 ENSG00000106546 PMC6321366__F3 Schematic overview of RAS and PI3K pathway and their interconnection PMC2774790__F6 Proteome Profile of Functional Mitochondria from Human Skeletal Muscle Using One-Dimensional Gel Electrophoresis and HPLC-ESI-MS/MS ENSG00000151726 ENSG00000073578 ENSG00000138029 ENSG00000163541 ENSG00000105953 ENSG00000172340 ENSG00000131828 ENSG00000127884 ENSG00000157184 ENSG00000117054 ENSG00000100412 ENSG00000122971 ENSG00000146701 ENSG00000123983 ENSG00000104325 ENSG00000062485 PMC4715161__F2 Transforming growth factorB (TGFB)-activated kinase 1 (TAK1) activation by TGFB in mesangial cells ENSG00000137834 ENSG00000175104 PMC3928987__F2 Cyclooxygenase pathway of AA PMC4023255__F5 TGFB family signaling for Müllerian duct regression ENSG00000107779 ENSG00000104899 ENSG00000170365 ENSG00000087245 ENSG00000135409 ENSG00000168036 PMC7692401__F1 Autophagy–lysosomal–endosomal system and the Parkinson’s disease (PD)-related proteins ENSG00000129003 ENSG00000100225 ENSG00000158828 ENSG00000069329 ENSG00000116675 ENSG00000127419 ENSG00000138760 PMC4374766__F5 Macrophage Gene Expression Associated with Remodeling of the Prepartum Rat Cervix: Microarray and Pathway Analyses ENSG00000122986 ENSG00000125740 ENSG00000082397 ENSG00000155926 ENSG00000152213 ENSG00000087085 ENSG00000137699 ENSG00000198598 ENSG00000121807 ENSG00000149781 ENSG00000010671 ENSG00000180353 ENSG00000205307 ENSG00000122025 ENSG00000082175 ENSG00000263528 ENSG00000166501 ENSG00000168398 ENSG00000139626 ENSG00000169851 ENSG00000162896 ENSG00000064195 ENSG00000140931 ENSG00000259207 ENSG00000081237 ENSG00000143878 ENSG00000170961 ENSG00000260314 ENSG00000115956 ENSG00000173898 ENSG00000126353 ENSG00000163072 PMC2522268__F1 Interferon-inducible antiviral effectors ENSG00000159128 ENSG00000105397 PMC6986718__F3 Impact of genotype, body weight and sex on the prenatal muscle transcriptome of Iberian pigs ENSG00000131910 ENSG00000127191 ENSG00000111816 PMC8602339__F1 Searching for DNA Damage: Insights From Single Molecule Analysis ENSG00000012061 ENSG00000101751 ENSG00000166169 ENSG00000136936 PMC3691611__F7 The proposed pathways that regulate astroglial CNTF ENSG00000242689 ENSG00000128342 ENSG00000168610 ENSG00000154096 PMC7530064__F9 Diagram of signaling pathway of IQGAP1 in regulation of VEGFR2-Src-Rac1 activation in choroidal angiogenesis ENSG00000291971 ENSG00000140575 ENSG00000160293 PMC4505740__F1 Molecular targeting of the mitogen-activated protein kinase (MAPK), PI3K, and CDK4 pathways and the associated mutation rates of potential molecular targets in advanced melanoma () ENSG00000157404 ENSG00000117020 ENSG00000002330 ENSG00000135446 ENSG00000177606 ENSG00000088256 ENSG00000171791 ENSG00000178568 ENSG00000196712 PMC9441553__F5 Metabolomics profiling reveals berberine-inhibited inflammatory response in human gingival fibroblasts by regulating the LPS-induced apoptosis signaling pathway ENSG00000158006 ENSG00000142192 ENSG00000071889 ENSG00000197746 ENSG00000110680 ENSG00000118094 ENSG00000145861 PMC5744685__F1 Targeting Metabolism for Cancer Therapy ENSG00000228716 ENSG00000102967 ENSG00000254550 PMC5744685__F8 Targeting Metabolism for Cancer Therapy ENSG00000099810 ENSG00000116984 PMC3740364__F1 Viral evasion mechanisms of early antiviral responses involving regulation of ubiquitin pathways ENSG00000183735 ENSG00000088888 ENSG00000131323 ENSG00000175104 ENSG00000121060 PMC7277093__F12 Multiple modes of AOAA’s action on H2S producing pathways and other transaminases in cancer cells ENSG00000125166 ENSG00000167701 PMC10348770__F1 Treg-mediated immunosuppression and resolution of lung inflammation ENSG00000141968 PMC7140047__F2 Rac1 signaling pathways and their biological significance ENSG00000106683 ENSG00000002330 ENSG00000163914 ENSG00000166851 ENSG00000168610 ENSG00000188747 ENSG00000182541 PMC6318069__F1 Three tooth agenesis-associated signaling pathways ENSG00000186197 ENSG00000135960 ENSG00000134982 ENSG00000168036 ENSG00000163132 ENSG00000180875 ENSG00000175104 ENSG00000168646 PMC6391768__F7 Schematic illustration of vitamin D/VDR’s regulation on HIF-1A as well as IFNG and IL-1B in oral keratinocytes ENSG00000134086 ENSG00000111537 ENSG00000125538 ENSG00000136869 PMC9597127__F3 Major STING combinatorial approaches with additive or synergistic effects ENSG00000164430 ENSG00000134982 ENSG00000168610 PMC9576928__F2 Advancement in understanding the role of ferroptosis in rheumatoid arthritis ENSG00000168003 ENSG00000161905 ENSG00000151012 ENSG00000115415 ENSG00000167468 ENSG00000072274 ENSG00000167996 ENSG00000111684 ENSG00000099194 ENSG00000115107 ENSG00000057663 ENSG00000123983 PMC6795686__F8 The signaling pathways regulating TREM2 phagocytosis and TREM2 modulation of NFKB phosphorylation/activation PMC3937046__F7 Neuronal circuit diagram of the light input pathway in the tadpole retina ENSG00000117707 ENSG00000016082 PMC4756853__F4 Pathways involved in thymidine synthesis in Escherichia coli, Drosophila melanogaster and humans ENSG00000228716 ENSG00000161634 ENSG00000128951 ENSG00000129187 PMC6770402__F5 Apoptosis pathways (hsa04210) and targets of cordycepin ENSG00000169814 ENSG00000083097 PMC6719933__F4 Transcriptional regulation of GRINA and its role in cell survival ENSG00000128272 ENSG00000139644 ENSG00000178719 PMC8107720__F5 Novel Regulatory Factors and Small-Molecule Inhibitors of FGFR4 in Cancer ENSG00000128272 ENSG00000160867 ENSG00000168610 PMC7281533__F4 Reactive oxygen species (ROS) promote cellular inflammatory response and oxidative damage, which may impact cell and tissue viability in the lungs ENSG00000205221 ENSG00000079999 PMC9338059__F2 KOPI: Kinase inhibitOr Proteome Impact analysis ENSG00000066926 ENSG00000104969 ENSG00000141086 ENSG00000163914 ENSG00000136997 ENSG00000054118 ENSG00000146648 PMC3969565__F1 Emergence and Evolutionary Analysis of the Human DDR Network: Implications in Comparative Genomics and Downstream Analyses ENSG00000143799 ENSG00000160551 ENSG00000087206 ENSG00000183765 ENSG00000012048 ENSG00000134899 ENSG00000079246 ENSG00000144554 ENSG00000101773 ENSG00000113558 ENSG00000164053 ENSG00000166167 ENSG00000138346 ENSG00000092853 ENSG00000103510 ENSG00000187790 ENSG00000115392 ENSG00000157212 ENSG00000111602 ENSG00000100387 ENSG00000132646 ENSG00000167986 ENSG00000139842 ENSG00000172977 ENSG00000096717 ENSG00000136936 ENSG00000130726 ENSG00000012061 ENSG00000284238 ENSG00000154920 ENSG00000077152 ENSG00000188827 ENSG00000105393 ENSG00000104517 ENSG00000291803 ENSG00000166851 ENSG00000175054 ENSG00000181625 ENSG00000132604 ENSG00000102226 ENSG00000198887 ENSG00000113318 ENSG00000138375 ENSG00000253729 ENSG00000101751 ENSG00000033800 ENSG00000124766 ENSG00000112130 ENSG00000149311 ENSG00000175643 ENSG00000197299 ENSG00000070950 ENSG00000178966 ENSG00000187736 ENSG00000149554 ENSG00000042088 ENSG00000095002 ENSG00000138385 PMC24579__F6 Integration of tyrosine kinase signaling to both cAMP and MAPK 1,2 pathways, resulting in cell cycle arrest and the reduction of MAPK 1,2 triggered proliferation ENSG00000188130 PMC8025927__F1 Schematic model depicting the mechanisms of meiotic arrest ENSG00000134057 ENSG00000134982 ENSG00000004487 ENSG00000159899 PMC3185772__F2 Regulation of Blood-brain barrier permeability, entry of WNV in the brain and factors involved in the pathogenesis of WNV-induced neuroinvasisve disease ENSG00000081041 ENSG00000107562 ENSG00000122194 ENSG00000164342 PMC7439920__F3 Critical role of HGMB1 in the complex interplay between apoptosis and autophagy ENSG00000189403 ENSG00000145782 PMC2635670__F1 Apoptosis pathways: The extrinsic or death receptor pathway (left) is triggered by members of the death receptor superfamily such as Fas ENSG00000168040 PMC6720817__F4 Intracellular signaling involved in cardioprotective response stimulated by ischemic postconditioning (PostC) in cardiac cells ENSG00000002330 PMC6720817__F3 Intracellular signaling involved in cardioprotective response stimulated by ischemic preconditioning (PreC) in cardiac cells ENSG00000002330 ENSG00000291971 ENSG00000146648 PMC9312859__F7 FGFR2c/PKCE Axis Controls MCL-1-Mediated Invasion in Pancreatic Ductal Adenocarcinoma Cells: Perspectives for Innovative Target Therapies ENSG00000198793 PMC2826677__F1 T-cell activation, proximal signalling complex and activation of transcription factors ENSG00000291603 ENSG00000213658 ENSG00000113263 ENSG00000124181 PMC9399644__F5 Advances in the study of HSP70 inhibitors to enhance the sensitivity of tumor cells to radiotherapy ENSG00000291971 ENSG00000146648 PMC6913740__F7 Carbohydrate metabolic pathway in ‘outer tissues', endosperm, and embryo of a barley grain and the differential transcript expression of involved genes in 18-6 transgenic grain from 7 to 24 DAP ENSG00000112977 ENSG00000116096 PMC7279407__F2 Simplified diagram of the core element of the three unfolded protein response (UPR) signaling branches of the endoplasmic reticulum (ER) ENSG00000128272 ENSG00000144895 ENSG00000100219 PMC3701867__F1 Scheme depicting the interactive roles of interferon, Trim, and Socs molecules regulating the innate response in SjS-susceptible C57BL/6.NOD-Aec1Aec2 mice ENSG00000089127 ENSG00000115415 ENSG00000198793 ENSG00000172005 ENSG00000132256 ENSG00000171206 ENSG00000136869 ENSG00000175104 ENSG00000168610 PMC4158832__F4 Planar cell polarity signaling in vertebrates ENSG00000107404 ENSG00000112655 PMC9663482__F9 Quercetin Suppresses Human Glioblastoma Migration and Invasion via GSK3B/Beta-catenin/ZEB1 Signaling Pathway ENSG00000168036 PMC7755285__F11 Using WGCNA (weighted gene co-expression network analysis) to identify the hub genes of skin hair follicle development in fetus stage of Inner Mongolia cashmere goat ENSG00000172830 ENSG00000137713 ENSG00000178585 ENSG00000198793 ENSG00000099860 ENSG00000116039 ENSG00000124762 ENSG00000136826 ENSG00000285069 ENSG00000182541 ENSG00000168003 ENSG00000158786 ENSG00000095739 ENSG00000126803 ENSG00000118515 ENSG00000143590 ENSG00000197943 ENSG00000107731 ENSG00000155760 ENSG00000158050 ENSG00000142627 ENSG00000132793 ENSG00000281877 ENSG00000108839 ENSG00000284816 ENSG00000111684 PMC3871910__F7 Proposed synergistic mechanisms for induction of mitotic cell death in endometrial cancer cells with mutant p53 ENSG00000276876 PMC11538000__F1 Pyroptosis regulation by Salmonella effectors ENSG00000278718 ENSG00000162711 ENSG00000163914 ENSG00000168404 PMC4071401__F11 Monoamine oxidase A mediates prostate tumorigenesis and cancer metastasis ENSG00000122691 ENSG00000112715 PMC6851023__F2 Pathways leading to IDO enzyme production and regulation ENSG00000106546 PMC11538000__F3 Salmonella plasmid virulence factors and pyroptosis ENSG00000278718 ENSG00000162711 ENSG00000091106 PMC4731283__F1 Evolving roles of canonical WNT signaling in stem cells and tumorigenesis: Implications in targeted cancer therapies ENSG00000134982 ENSG00000167941 ENSG00000183579 ENSG00000168036 ENSG00000108375 PMC11932863__F6 Targeting cell cycle arrest in breast cancer by phytochemicals from Caryto urens L. fruit ethyl acetate fraction: in silico and in vitro validation ENSG00000171320 ENSG00000118007 ENSG00000108055 ENSG00000134982 ENSG00000167513 ENSG00000164190 ENSG00000277273 ENSG00000129933 ENSG00000117399 ENSG00000140534 ENSG00000276876 ENSG00000093009 ENSG00000141446 ENSG00000137812 ENSG00000145604 ENSG00000172167 ENSG00000101972 ENSG00000132646 ENSG00000081377 ENSG00000123374 ENSG00000164754 ENSG00000071539 PMC9205109__F8 Geniposide suppresses NLRP3 inflammasome-mediated pyroptosis via the AMPK signaling pathway to mitigate myocardial ischemia/reperfusion injury ENSG00000278718 ENSG00000162711 ENSG00000265972 PMC5492985__F2 Canonical Notch Signaling Pathway: Structural And Biochemical Insights Into Shape, Sugar, And Force ENSG00000168214 ENSG00000073614 ENSG00000165097 PMC9395613__F1 Advances in cell death mechanisms involved in viral myocarditis ENSG00000162711 ENSG00000198793 ENSG00000168040 ENSG00000026103 PMC4505457__F10 Model for DAXX-mediated induction of tumorigenesis ENSG00000177169 PMC1559555__F1 GSH metabolic pathway ENSG00000023909 ENSG00000106459 PMC7573576__F4 Synthetic lethal pathway: multiple pathways ENSG00000163914 ENSG00000131095 ENSG00000175104 ENSG00000179348 ENSG00000106459 PMC7868569__F10 Chrysophanol-mediated suppression of the inflammatory response ENSG00000171720 ENSG00000125538 ENSG00000189403 PMC7573576__F3 Synthetic lethal pathway: dual pathways ENSG00000143799 ENSG00000012048 PMC7573576__F2 Synthetic lethal pathway: single pathway ENSG00000117713 ENSG00000066117 ENSG00000139613 ENSG00000049618 ENSG00000136518 ENSG00000127616 PMC7643807__F1B Activin Receptor-Ligand Trap for the Treatment of Beta-thalassemia: A Serendipitous Discovery ENSG00000135414 ENSG00000130283 ENSG00000266524 ENSG00000184344 PMC7015255__F6 Changes provoked by aerobic exercise training on microRNA‐1 downstream‐associated pathways in patients with chronic heart failure with reduced ejection fraction (HFrEF) ENSG00000198793 ENSG00000081189 PMC2278039__F2 FIP200, a key signaling node to coordinately regulate various cellular processes ENSG00000198793 ENSG00000127191 ENSG00000139687 PMC7643807__F1A Activin Receptor-Ligand Trap for the Treatment of Beta-thalassemia: A Serendipitous Discovery ENSG00000135414 ENSG00000130283 ENSG00000266524 ENSG00000184344 PMC7378646__F2 Crosstalk between the Hippo-YAP1/TAZ pathway and Wnt signaling ENSG00000004975 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 ENSG00000150457 ENSG00000131023 PMC7378646__F1 Overview of Hippo-YAP1/TAZ pathway and its role in cardiac biology ENSG00000150457 ENSG00000131023 PMC7378646__F4 Crosstalk between the Hippo-YAP1/TAZ pathway and GPCR signaling ENSG00000038382 ENSG00000150457 ENSG00000131023 PMC7378646__F3 Crosstalk between the Hippo-YAP1/TAZ pathway and BMP signaling ENSG00000170365 ENSG00000150457 ENSG00000131023 PMC4207610__F7 HIPPO Pathway Members Restrict SOX2 to the Inner Cell Mass Where It Promotes ICM Fates in the Mouse Blastocyst ENSG00000165556 ENSG00000141448 PMC4442456__F1 Changes in the expression of cell cycle-related genes during MNV-1 infection ENSG00000149311 ENSG00000111554 ENSG00000105329 ENSG00000170027 ENSG00000123374 ENSG00000116717 ENSG00000101224 PMC6815541__F1 Probable mechanisms of the effects produced by lncRNAs on SCI ENSG00000065559 ENSG00000136869 ENSG00000255690 ENSG00000168778 ENSG00000136826 PMC4441984__F4 Scheme of the IL-11/STAT3/CDX2 pathway ENSG00000165556 ENSG00000115415 ENSG00000198793 ENSG00000171791 ENSG00000112715 ENSG00000168610 PMC5889847__F3 CircRNAs function as ceRNAs in the regulation of apoptosis in tumor cells ENSG00000120868 ENSG00000168040 PMC8495397__F3 Hippo pathway: a renewed insight in the craniofacial diseases and hard tissue remodeling ENSG00000173039 ENSG00000172936 ENSG00000150457 ENSG00000175104 ENSG00000131023 PMC8129516__F1 Glycogen Synthase Kinase 3B Modulates the Inflammatory Response Activated by Bacteria, Viruses, and Parasites ENSG00000107404 ENSG00000239732 ENSG00000163251 ENSG00000115415 ENSG00000187554 ENSG00000168036 ENSG00000172936 ENSG00000136869 ENSG00000277641 ENSG00000168610 ENSG00000157240 PMC3635536__F5 Signaling Pathways in Schizophrenia: emerging targets and therapeutic strategies ENSG00000138798 ENSG00000198793 ENSG00000115904 PMC3140475__F5 Proteomic Biomarkers for Acute Interstitial Lung Disease in Gefitinib-Treated Japanese Lung Cancer Patients ENSG00000196136 ENSG00000261701 ENSG00000113905 ENSG00000117601 ENSG00000244731 ENSG00000236625 ENSG00000162444 PMC4212952__F4 Network pathway analysis of differentially expressed genes in different subgroups of patients and controls ENSG00000138378 ENSG00000164093 ENSG00000133317 PMC5992512__F2 Dynamic response of tumor cells to fluid shear stress ENSG00000107779 ENSG00000170365 PMC7892237__F3 Autophagy: binding of growth factors to its receptor (tyrosine kinase) gets activated leads to the activation of PIP3K which phosphorylates PIP2 to PIP3 and recruits protein kinases PDK1 and AKT to inactivate TSC and RHEB ENSG00000198793 ENSG00000112561 ENSG00000140464 PMC6059692__F4 Predicted regulatory networks affected by sinomenine treatment via Ingenuity®Pathway Analysis ENSG00000066468 ENSG00000154305 ENSG00000105329 ENSG00000149136 ENSG00000111799 ENSG00000164327 ENSG00000113569 ENSG00000170367 ENSG00000080839 ENSG00000088387 ENSG00000106546 PMC7825621__F2 miRNA targeted network of cancer signaling including senescence ENSG00000112576 ENSG00000132646 ENSG00000164399 ENSG00000162521 ENSG00000092067 ENSG00000115310 ENSG00000139154 ENSG00000074266 ENSG00000132510 ENSG00000178691 ENSG00000118971 ENSG00000149187 PMC11758815__F11 Cobalt signaling ENSG00000092439 ENSG00000110395 PMC8222109__F1 Inflammatory Profile in a Canine Model of Hypothermic Circulatory Arrest ENSG00000162889 ENSG00000077150 ENSG00000175899 ENSG00000175104 ENSG00000127191 ENSG00000168610 ENSG00000132693 ENSG00000028137 ENSG00000133818 PMC3690356__F1 Calcium channels in T cells ENSG00000167323 ENSG00000134982 PMC7924042__F7 Catalpol on AMPK pathway in alleviating DN ENSG00000278718 ENSG00000162711 PMC7924042__F6 Molecular mechanism of catalpol in diabetic nephropathy ENSG00000087245 ENSG00000005882 ENSG00000135446 ENSG00000150907 ENSG00000137193 ENSG00000112561 ENSG00000007908 ENSG00000171791 ENSG00000162692 ENSG00000164305 ENSG00000178726 PMC7924042__F9 Cardioprotective mechanism of catalpol in MI ENSG00000132906 ENSG00000177169 ENSG00000110497 ENSG00000123395 ENSG00000002330 ENSG00000126775 ENSG00000148572 ENSG00000145782 ENSG00000164305 ENSG00000057663 PMC8304138__F2 Retinoids as Chemo-Preventive and Molecular-Targeted Anti-Cancer Therapies ENSG00000095596 PMC11796038__F8 CTSB induces ferroptosis via SAT1-mediated lipid peroxidation, mitochondrial damage and MAPK signalling pathway activation ENSG00000167468 PMC7924042__F8 Cardioprotective mechanism of catalpol in diabetic cardiomyopathy ENSG00000164305 PMC8945446__F2 Therapeutic Approaches Targeting Proteins in Tumor-Associated Macrophages and Their Applications in Cancers ENSG00000140992 ENSG00000087245 ENSG00000137673 ENSG00000275385 ENSG00000137033 ENSG00000198793 ENSG00000170558 ENSG00000168036 ENSG00000168610 ENSG00000115602 ENSG00000108691 ENSG00000111801 ENSG00000118785 ENSG00000101255 ENSG00000136869 ENSG00000136235 ENSG00000100985 PMC4138085__F2 Transcriptional Profiling in Rat Hair Follicles following Simulated Blast Insult: A New Diagnostic Tool for Traumatic Brain Injury ENSG00000100906 ENSG00000050748 ENSG00000065559 ENSG00000150455 ENSG00000105639 ENSG00000135341 ENSG00000127666 ENSG00000161955 ENSG00000183735 ENSG00000226275 ENSG00000111537 ENSG00000105397 ENSG00000263528 ENSG00000177606 ENSG00000172936 ENSG00000175104 ENSG00000113302 ENSG00000184216 PMC9641982__F2 Innate immune mechanisms of mRNA vaccines ENSG00000169245 ENSG00000213928 ENSG00000115415 ENSG00000145321 ENSG00000172936 ENSG00000276561 ENSG00000164342 PMC3900522__F3 Fibroblast Growth Factor Receptor 3 Interacts with and Activates TGFBeta-Activated Kinase 1 Tyrosine Phosphorylation and NFKB Signaling in Multiple Myeloma and Bladder Cancer ENSG00000163406 ENSG00000151726 ENSG00000071073 ENSG00000150991 ENSG00000095739 ENSG00000269335 ENSG00000118515 ENSG00000107372 ENSG00000167653 ENSG00000188338 PMC9442203__F8 Anti-proliferation and apoptosis-inducing effects of dihydroartemisinin on SH-SY5Y cells and metabolomic analysis ENSG00000039537 ENSG00000166278 PMC4414490__F1 Activation and Function of Small GTPases Rho, Rac, and Cdc42 During Gastrulation ENSG00000070831 ENSG00000100592 PMC8247097__F1 Correction to: Pyroptosis: a new paradigm of cell death for fighting against cancer ENSG00000162711 ENSG00000150782 ENSG00000002330 ENSG00000163568 ENSG00000125538 ENSG00000091592 ENSG00000145649 ENSG00000189403 ENSG00000091106 PMC3037835__F5 Major pathways of lipid metabolism in yeast ENSG00000124102 ENSG00000067064 ENSG00000163624 ENSG00000146005 ENSG00000173599 ENSG00000166123 ENSG00000135517 PMC7715033__F1 Immune and molecular mechanisms of FSGS pathogenesis ENSG00000121807 ENSG00000175505 PMC3461905__F2 Molecular pathogenesis of mantle cell lymphoma ENSG00000148400 ENSG00000010810 ENSG00000186716 ENSG00000198793 ENSG00000171791 ENSG00000137845 ENSG00000010671 PMC5992512__F3 Various factors activated by fluid shear stress (FSS) can induce tumor cells metastasis ENSG00000125538 ENSG00000198793 PMC5852671__F3 Significance of selenium in cancer stem cell metabolism ENSG00000149311 ENSG00000078237 ENSG00000284194 PMC10968114__F6 TSG-6 Inhibits the NFKB Signaling Pathway and Promotes the Odontogenic Differentiation of Dental Pulp Stem Cells via CD44 in an Inflammatory Environment ENSG00000026508 ENSG00000152591 PMC7970140__F2 Abnormal metabolic pathways ENSG00000131473 ENSG00000125166 ENSG00000067057 ENSG00000073578 ENSG00000117118 ENSG00000169710 ENSG00000105953 ENSG00000172340 ENSG00000131828 ENSG00000070669 ENSG00000074800 ENSG00000100412 ENSG00000173599 ENSG00000146701 ENSG00000082212 ENSG00000091140 ENSG00000115419 ENSG00000159399 ENSG00000169299 ENSG00000141526 ENSG00000062485 PMC7663488__F3 Impaired regulation of lipid metabolism by AMPK in renal cells in obesity/diabetes ENSG00000135218 ENSG00000113161 ENSG00000026103 PMC7935450__F1 CGAS-STING signaling pathway ENSG00000183735 ENSG00000164430 PMC8698071__F10 Resveratrol Relieved Acute Liver Damage in Ducks (Anas platyrhynchos) Induced by AFB1 via Modulation of Apoptosis and Nrf2 Signaling Pathways ENSG00000181019 ENSG00000096717 ENSG00000023909 ENSG00000079999 PMC5757132__F7 Proposed mechanisms of miR-146a in alleviating experimental autoimmune anterior uveitis (EAAU) ENSG00000138378 ENSG00000115415 ENSG00000175104 PMC10384750__F1 Exploring the mTOR Signalling Pathway and Its Inhibitory Scope in Cancer ENSG00000177169 ENSG00000198793 ENSG00000163914 ENSG00000144848 ENSG00000118515 ENSG00000167965 PMC11588768__F2 TGP treatment: A TGP regulates the Wnt/Beta-catenin signaling pathway to treat IgAVN ENSG00000142192 ENSG00000178573 ENSG00000167468 ENSG00000136826 PMC10985998__F8 Expression of genes in carbon, ATP, NADPH metabolism in C ENSG00000197713 ENSG00000105953 PMC10384750__F3 Exploring the mTOR Signalling Pathway and Its Inhibitory Scope in Cancer ENSG00000169047 PMC10384750__F2 Exploring the mTOR Signalling Pathway and Its Inhibitory Scope in Cancer ENSG00000198793 ENSG00000164327 ENSG00000167965 PMC6785663__F1 Classic view on the pathogenesis of celiac disease ENSG00000134982 ENSG00000164136 ENSG00000105656 PMC10384750__F6 Exploring the mTOR Signalling Pathway and Its Inhibitory Scope in Cancer ENSG00000169047 ENSG00000198793 PMC8264592__F2 Local Anesthetic Lidocaine and Cancer: Insight Into Tumor Progression and Recurrence ENSG00000291971 ENSG00000198793 PMC7848718__F5 Longitudinal shear stress response in human endothelial cells to atheroprone and atheroprotective conditions ENSG00000112576 ENSG00000107562 ENSG00000105329 ENSG00000110799 ENSG00000109320 ENSG00000086991 ENSG00000129355 ENSG00000127528 ENSG00000007908 ENSG00000114573 ENSG00000091879 ENSG00000112715 ENSG00000136826 ENSG00000211445 ENSG00000172216 ENSG00000181019 ENSG00000135446 ENSG00000128052 ENSG00000277236 ENSG00000134853 ENSG00000181652 ENSG00000162692 ENSG00000171608 ENSG00000125968 PMC7916550__F5 Ingenuity Pathway Analysis downstream function prediction of the overlapping differentially expressed genes from the liver 3 h heat-control contrast and 4-week to 3 h control time contrast ENSG00000102053 ENSG00000119705 ENSG00000123219 ENSG00000102683 ENSG00000077009 ENSG00000132603 ENSG00000288369 ENSG00000134013 ENSG00000174917 ENSG00000101003 ENSG00000049239 ENSG00000115020 ENSG00000171848 ENSG00000127527 ENSG00000176136 ENSG00000134809 PMC7848718__F4 Longitudinal shear stress response in human endothelial cells to atheroprone and atheroprotective conditions ENSG00000116044 ENSG00000109320 ENSG00000086991 ENSG00000008394 ENSG00000140465 ENSG00000158125 ENSG00000211445 ENSG00000184470 ENSG00000181019 ENSG00000100348 ENSG00000185591 ENSG00000277897 ENSG00000074771 PMC6544834__F1 Progress in the Management of Malignant Pleural Mesothelioma in 2017 ENSG00000163930 ENSG00000186575 PMC9350707__F4 Immunomodulatory role of T helper cells in rheumatoid arthritis ENSG00000125538 PMC10492386__F10 EVs interacting with immune cells ENSG00000162711 ENSG00000172936 ENSG00000136869 PMC7139827__F1 Endoplasmic reticulum (ER) signaling pathway and the ER–mitochondria pathway triggered by natural compounds ENSG00000128272 ENSG00000144895 ENSG00000127191 PMC4358941__F2 Comparative Metabolic Analysis of CHO Cell Clones Obtained through Cell Engineering, for IgG Productivity, Growth and Cell Longevity ENSG00000122966 ENSG00000172005 ENSG00000146701 PMC6563521__F5 Upregulated genes in proteasome biosynthetic pathway at 24 h after inoculation using F ENSG00000197713 ENSG00000111537 ENSG00000163902 ENSG00000198576 ENSG00000132383 ENSG00000132963 PMC7429955__F7 LINC00675 activates androgen receptor axis signaling pathway to promote castration-resistant prostate cancer progression ENSG00000179348 PMC5966875__F1 Synthesis and metabolism of common bile acids in human ENSG00000158825 ENSG00000099377 ENSG00000135929 PMC6523616__F8 A transcriptional and post-transcriptional regulatory system mediating the hepatic metabolic switch in chickens ENSG00000196591 ENSG00000169710 ENSG00000166123 ENSG00000052802 PMC11617665__F1 Metabolic signaling pathways modulated by PTP1B ENSG00000169047 ENSG00000168610 PMC8171523__F1 Wnt信号通路对软骨和软骨下骨双靶向调控及其在骨关节炎进展中的作用 ENSG00000134982 ENSG00000163914 ENSG00000168036 PMC4424075__F3 Innate Immune Evasion by Filoviruses ENSG00000105397 ENSG00000142166 PMC4424075__F2 Innate Immune Evasion by Filoviruses ENSG00000183735 ENSG00000088888 ENSG00000131323 PMC7029263__F2 TRPV1-CNTF signaling cascade in PD ENSG00000242689 ENSG00000168610 ENSG00000196689 PMC7029263__F1 Wnt/Beta-catenin signaling cascade in Parkinson's disease ENSG00000138795 ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC3725164__F1 TGFB signaling pathway ENSG00000157933 PMC10218870__F1 Schematic diagram showing the main molecular targets of luteolin during the initial steps of the metastatic cascade ENSG00000148400 ENSG00000291971 ENSG00000170558 ENSG00000198793 ENSG00000168610 PMC8899398__F3 Lactoferrin: A Nutraceutical with Activity against Colorectal Cancer ENSG00000120868 PMC11036006__F13 Exploring the neuroprotection of the combination of astragaloside A, chlorogenic acid and scutellarin in treating chronic cerebral ischemia via network analysis and experimental validation ENSG00000124102 PMC11273248__F1 Flavonoid compounds exerting protective effects against brain injury after ICH ENSG00000162711 ENSG00000181019 ENSG00000175104 ENSG00000164305 PMC8168427__F7 Proposed mechanisms of ALDH2*2 to induce atrial fibrillation ENSG00000128918 PMC4752785__F3 Scheme of the molecular mechanisms that systematic exposure to cigarette smoke can influence during carcinogenesis of the mammary gland ENSG00000291971 ENSG00000171791 ENSG00000146648 PMC4752785__F2 Scheme of the molecular mechanisms that ethanol consumption can influence during carcinogenesis of the mammary gland ENSG00000180210 ENSG00000109321 ENSG00000163235 ENSG00000078053 ENSG00000146648 PMC11273248__F2 Flavonoid compounds exerting protective effects on SAH ENSG00000162711 ENSG00000181019 ENSG00000127528 ENSG00000096717 ENSG00000164305 PMC8671582__F2 Pathway network analysis of the significantly differentially expressed lncRNAs and mRNAs ENSG00000145431 ENSG00000178814 ENSG00000143252 ENSG00000162551 ENSG00000198793 ENSG00000135932 ENSG00000132357 ENSG00000091106 ENSG00000100504 ENSG00000198734 ENSG00000197208 ENSG00000276068 PMC6581439__F6 Shown are the edges whose scores exceeded the threshold ; edges are labelled with their scores ENSG00000163435 ENSG00000102034 ENSG00000203783 ENSG00000186654 PMC5328618__F8 Model for how APC mutations affect insulin-induced dynein movement toward MT minus ends ENSG00000166579 ENSG00000134982 PMC5027283__F5 Oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway ENSG00000155792 ENSG00000066135 PMC4439562__F4 GPCR (or GPR) signaling in the regulation of Beta-cell proliferation ENSG00000159224 ENSG00000139515 ENSG00000168036 ENSG00000123374 ENSG00000096717 ENSG00000118971 ENSG00000010310 ENSG00000146648 PMC3481051__F3 The different main molecular pathways that are involved in neuronal stress response ENSG00000134086 ENSG00000124571 PMC4439562__F3 Cadherin and integrin signaling pathways ENSG00000134982 ENSG00000168036 PMC4439562__F1 Cytokine and hormone signaling through JAK-STAT pathways ENSG00000178188 ENSG00000129167 ENSG00000113494 PMC9687146__F5 Cisplatin Induces Senescent Lung Cancer Cell-Mediated Stemness Induction via GRP78/Akt-Dependent Mechanism ENSG00000149311 ENSG00000175054 ENSG00000026508 ENSG00000123374 PMC5137220__F1 Summary of genetic and pharmacological evidence implicating Wnt signaling in developmental cognitive disorders ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000198793 ENSG00000168036 PMC12078813__F8 TD formation ENSG00000138798 PMC3753830__F1 Schematic overview of signalling pathways and drug targets currently under investigation in CML research ENSG00000198793 ENSG00000168036 ENSG00000128602 ENSG00000275565 ENSG00000140464 PMC6174864__F8 A working model illustrating HHcy-induced ER oxidative stress and inflammation in endothelial cells ENSG00000197930 ENSG00000162692 ENSG00000116157 PMC6388721__F3 Simplified illustration of TXNIP role in presumptive pathways involved in endothelial dysfunction ENSG00000162711 ENSG00000291971 ENSG00000127528 ENSG00000265972 ENSG00000162692 PMC3078022__F1 Tumor heterogeneity and strategies to overcome kinase inhibitor resistance in cancer: Lessons from melanoma ENSG00000157764 PMC4297928__F1 Simplified pathophysiology of reactive oxygen species (ROS) and etheno-DNA adduct formation ENSG00000005381 PMC8041338__F1 Imipridones in targeting mitochondrial metabolism in cancer cells ENSG00000128272 ENSG00000166855 ENSG00000171791 ENSG00000125656 PMC5451507__F2 Congenital heart defect BioCore (CHD-BioCore): strategy and frame work ENSG00000291971 ENSG00000154059 ENSG00000100744 ENSG00000146648 PMC5532733__F2 Molecular mechanisms linking geranylgeranyl diphosphate synthase to cell survival and proliferation ENSG00000152904 ENSG00000113161 PMC2174972__F7 The Viral Oncoprotein LMP1 Exploits TRADD for Signaling by Masking Its Apoptotic Activity ENSG00000102871 ENSG00000175104 PMC8630009__F6 Revealing the efficacy-toxicity relationship of Fuzi in treating rheumatoid arthritis by systems pharmacology ENSG00000102871 ENSG00000007908 ENSG00000128342 ENSG00000168040 PMC2824905__F2 IFITM Proteins Mediate the Innate Immune Response to Influenza A H1N1 Virus, West Nile Virus and Dengue Virus ENSG00000111581 ENSG00000162630 ENSG00000105193 ENSG00000100883 ENSG00000163510 ENSG00000065457 ENSG00000117410 ENSG00000166136 ENSG00000236826 ENSG00000136436 ENSG00000163463 ENSG00000149972 ENSG00000100028 ENSG00000052344 ENSG00000099139 ENSG00000161847 ENSG00000185482 ENSG00000100347 ENSG00000084733 ENSG00000184432 ENSG00000277707 ENSG00000149564 ENSG00000124217 ENSG00000164587 ENSG00000151365 ENSG00000130810 ENSG00000083845 ENSG00000183648 ENSG00000000457 ENSG00000188739 ENSG00000124155 ENSG00000128829 ENSG00000275272 ENSG00000175390 ENSG00000198612 ENSG00000111481 ENSG00000134775 ENSG00000164414 ENSG00000117411 ENSG00000147123 ENSG00000008988 ENSG00000134419 ENSG00000175467 ENSG00000204956 ENSG00000164609 ENSG00000198947 ENSG00000021776 ENSG00000007306 ENSG00000147684 ENSG00000129450 ENSG00000100564 ENSG00000137574 ENSG00000274442 ENSG00000125743 ENSG00000185883 ENSG00000142541 ENSG00000115524 ENSG00000106263 ENSG00000102898 ENSG00000142089 ENSG00000110713 ENSG00000276429 ENSG00000105723 ENSG00000168490 PMC8630009__F8 Revealing the efficacy-toxicity relationship of Fuzi in treating rheumatoid arthritis by systems pharmacology ENSG00000166278 PMC7285601__F1 Simplified schematic of pyrimidine nucleotide synthesis showing enzymes targeted for cancer therapy ENSG00000188641 ENSG00000158825 ENSG00000047230 ENSG00000112759 ENSG00000102967 ENSG00000129187 ENSG00000198246 ENSG00000084774 ENSG00000197506 PMC4155023__F3 Growth factor- and cytokine-regulated pathways are activated during liver regeneration ENSG00000132478 ENSG00000168610 ENSG00000122194 PMC6381212__F8 Increased expression of lncRNA CASC9 promotes tumor progression by suppressing autophagy-mediated cell apoptosis via the AKT/mTOR pathway in oral squamous cell carcinoma ENSG00000198793 PMC3356053__F10 Most significant canonical pathway from this study ENSG00000099330 ENSG00000136997 PMC7878670__F2 IGF-1R trafficking routes and signaling to the mitochondria and from the Golgi and the Nucleus ENSG00000138795 ENSG00000169047 ENSG00000177606 ENSG00000019549 ENSG00000153201 ENSG00000168646 ENSG00000140443 PMC7415793__F4 Treg in cardiomyocyte regeneration ENSG00000109321 ENSG00000077984 ENSG00000106178 PMC8836222__F10 Comparative Transcriptome Analysis Reveals Mechanisms of Folate Accumulation in Maize Grains ENSG00000095059 ENSG00000136877 ENSG00000137563 PMC3057147__F1 Top associated network functions for miR-141 and miR-200c PMC8541208__F5 Not-So-Good, the Bad and the Ugly: HPV E5, E6 and E7 Oncoproteins in the Orchestration of Carcinogenesis ENSG00000102871 ENSG00000168040 ENSG00000127191 ENSG00000026103 PMC8541208__F4 Not-So-Good, the Bad and the Ugly: HPV E5, E6 and E7 Oncoproteins in the Orchestration of Carcinogenesis ENSG00000160445 ENSG00000100387 ENSG00000154582 PMC5009010__F9 Schematic signal transduction network representing the effect of chronic alcohol on protein balance in eWAT ENSG00000177169 ENSG00000284161 ENSG00000167658 ENSG00000145782 ENSG00000057663 PMC6585021__F4 The molecular mechanism of OM antifibrogenic effects.OM could attenuate HSCs activation induced by TGFB1 in vitro by down-regulating the expression of miR-195 and up-regulating Smad7 PMC8850260__F8 Tetramethylpyrazine Alleviates Endothelial Glycocalyx Degradation and Promotes Glycocalyx Restoration via TLR4/NFKB/HPSE1 Signaling Pathway During Inflammation ENSG00000115884 ENSG00000136869 ENSG00000162692 PMC6515079__F10 Network analysis of proteome datasets in M2 polarized (vs ENSG00000168028 ENSG00000196531 ENSG00000144485 ENSG00000186395 ENSG00000165119 ENSG00000188822 ENSG00000170027 ENSG00000113318 ENSG00000088247 ENSG00000134709 ENSG00000092199 ENSG00000161960 PMC5972417__F7 The FA pathway and SPR-5 cooperate in DNA repair and regulation of histone demethylation ENSG00000144554 ENSG00000187790 ENSG00000276787 PMC5355638__F2 Mechanisms of RSV T-cell interference as a potential immune evasion strategy ENSG00000198793 ENSG00000026103 PMC7976584__F6 MiR-362-driven TGFB/SMAD signaling modulation of cell migration and invasion: a proposed scheme ENSG00000124216 ENSG00000276644 PMC2469272__F2 LPS signaling [modified from O’Neill and Bowie () with permission] ENSG00000170458 ENSG00000172005 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000276561 PMC7737291__F1 Genes found altered in Central Carbon Metabolism (CCM) pathway in gingivo-buccal oral cancer ENSG00000152266 ENSG00000122966 ENSG00000087842 PMC4941333__F9 Aquaporin 3 promotes the stem-like properties of gastric cancer cells via Wnt/GSK-3B/Beta-catenin pathway ENSG00000026508 ENSG00000168036 PMC6055056__F4 FoxO signaling pathway ENSG00000145604 ENSG00000149311 ENSG00000087095 ENSG00000127528 ENSG00000123374 ENSG00000145782 ENSG00000168610 ENSG00000168685 ENSG00000047932 PMC6055056__F5 Signaling pathways involved in susceptibility to Salmonella enteritidis infection ENSG00000104365 ENSG00000171105 ENSG00000005339 ENSG00000169047 ENSG00000110324 ENSG00000145391 ENSG00000215788 ENSG00000064300 ENSG00000121966 ENSG00000197461 ENSG00000150782 ENSG00000131724 ENSG00000243646 ENSG00000051128 ENSG00000171608 ENSG00000146648 ENSG00000141655 PMC7110972__F7 Proposed rES/ID1/TSP-1 signaling pathway ENSG00000135218 ENSG00000125968 PMC3889250__F1 The BDNF signaling network ENSG00000185634 ENSG00000198053 ENSG00000100906 ENSG00000134982 ENSG00000291971 ENSG00000162551 ENSG00000198793 ENSG00000173039 ENSG00000167658 ENSG00000116701 ENSG00000148082 ENSG00000177606 ENSG00000285485 PMC8257821__F6 PTEN Lipid Phosphatase Activity Enhances Dengue Virus Production through Akt/FoxO1/Maf1 Signaling ENSG00000169710 ENSG00000179632 PMC4172469__F7 Estrogen Regulation of microRNAs, Target Genes, and microRNA Expression Associated with Vitellogenesis in the Zebrafish ENSG00000145604 ENSG00000124102 ENSG00000118007 ENSG00000101972 ENSG00000135446 ENSG00000132646 ENSG00000123374 ENSG00000205250 ENSG00000105810 ENSG00000277273 ENSG00000276876 ENSG00000093009 PMC7599606__F2 An integrative view of glutamine metabolism ENSG00000172005 ENSG00000169710 ENSG00000115419 PMC8728518__F2 PLK1 inhibition-based combination therapies for cancer management ENSG00000141867 ENSG00000291971 ENSG00000198793 ENSG00000166851 ENSG00000113851 ENSG00000168610 ENSG00000146648 PMC4393358__F3 FGF signaling pathways ENSG00000107338 ENSG00000110395 ENSG00000244405 ENSG00000150907 ENSG00000175832 ENSG00000099942 ENSG00000115290 PMC3759480__F3 Wnt/Beta-catenin signaling was activated in gemcitabine resistant NSCLC cell lines ENSG00000177606 ENSG00000136997 ENSG00000026508 ENSG00000196628 PMC5336655__F4 Example of a visualisation of a significant pathway using the SetRank package ENSG00000245848 ENSG00000157404 ENSG00000159216 ENSG00000066336 ENSG00000170458 ENSG00000005381 ENSG00000067955 ENSG00000140464 PMC4393358__F1 FGF and FGFR families ENSG00000125538 ENSG00000167900 PMC5593677__F2 Promising landscape for regulating macrophage polarization: epigenetic viewpoint ENSG00000107562 ENSG00000115415 ENSG00000134070 ENSG00000175104 ENSG00000184216 PMC9671555__F4 Altered Intestinal ACE2 Levels Are Associated With Inflammation, Severe Disease, and Response to Anti-Cytokine Therapy in Inflammatory Bowel Disease ENSG00000174358 ENSG00000130234 PMC9441790__F3 Primary cilium in kidney development, function and disease ENSG00000134982 ENSG00000168036 PMC6050292__F7 Dynamics of S1P- and ceramide-synthesis pathway ENSG00000167769 ENSG00000103222 ENSG00000070610 ENSG00000067113 ENSG00000118777 ENSG00000183018 ENSG00000141934 ENSG00000172292 ENSG00000078124 ENSG00000162407 ENSG00000128699 ENSG00000285281 ENSG00000168610 ENSG00000135587 ENSG00000143418 ENSG00000139624 ENSG00000100422 ENSG00000063176 ENSG00000223802 ENSG00000154227 ENSG00000118785 ENSG00000143753 ENSG00000292130 ENSG00000164023 ENSG00000188611 ENSG00000172057 ENSG00000166224 ENSG00000123353 ENSG00000148154 ENSG00000168350 ENSG00000163082 PMC9441790__F2 Primary cilium in kidney development, function and disease ENSG00000162552 ENSG00000168036 ENSG00000276799 PMC7468582__F9 WD Repeat Domain 1 Deficiency Inhibits Neointima Formation in Mice Carotid Artery by Modulation of Smooth Muscle Cell Migration and Proliferation ENSG00000168610 PMC8305593__F1 An immunotherapeutic approach to decipher the role of long non-coding RNAs in cancer progression, resistance and epigenetic regulation of immune cells ENSG00000138378 ENSG00000111537 ENSG00000113520 ENSG00000171791 ENSG00000196363 PMC8992454__F1 Barriers to achieving a cure in lymphoma ENSG00000140992 ENSG00000291603 ENSG00000155926 ENSG00000167604 ENSG00000198793 ENSG00000115904 ENSG00000171791 ENSG00000121879 ENSG00000141968 ENSG00000010671 ENSG00000177455 ENSG00000166501 ENSG00000124181 ENSG00000198286 ENSG00000104365 ENSG00000105369 ENSG00000100906 ENSG00000163874 ENSG00000149091 ENSG00000127191 ENSG00000281614 ENSG00000118503 ENSG00000186716 ENSG00000177606 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000171608 ENSG00000155629 PMC10971254__F10 Binding of IL-33 to its receptor induces the MyD88/IRAK1/IRAK4/TRAF6/NFKB- dependent signaling pathway and the TRAF6/MAPK/AP-1-dependent signaling pathway ENSG00000137033 ENSG00000172936 ENSG00000175104 PMC2909379__F3 Hox Genes and Regional Patterning of the Vertebrate Body Plan ENSG00000165556 ENSG00000123364 PMC9578855__F7 Eucommia ulmoides Oliver's Multitarget Mechanism for Treatment of Ankylosing Spondylitis: A Study Based on Network Pharmacology and Molecular Docking PMC10498433__F8 Lactate-induced oxidative stress ENSG00000149968 ENSG00000086991 ENSG00000159399 PMC10960062__F7 Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity ENSG00000131473 ENSG00000163939 ENSG00000284774 ENSG00000005339 ENSG00000169856 ENSG00000073578 ENSG00000129514 ENSG00000172340 ENSG00000181192 ENSG00000069667 ENSG00000132170 ENSG00000245848 ENSG00000141867 ENSG00000165632 ENSG00000172216 ENSG00000100412 ENSG00000164754 ENSG00000288325 ENSG00000146701 ENSG00000062485 PMC10960062__F6 Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity ENSG00000262785 ENSG00000005339 ENSG00000113492 ENSG00000129514 ENSG00000117707 ENSG00000185049 ENSG00000069667 ENSG00000132170 ENSG00000141867 ENSG00000101972 ENSG00000165632 ENSG00000172482 ENSG00000196498 ENSG00000100219 ENSG00000288325 ENSG00000136872 ENSG00000166123 ENSG00000167701 PMC10960062__F5 Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity ENSG00000245848 ENSG00000141867 ENSG00000005339 ENSG00000172216 ENSG00000169856 ENSG00000129514 ENSG00000164754 ENSG00000100219 ENSG00000288325 ENSG00000185049 ENSG00000132170 PMC4362638__F4 IPA-inferred Sertoli cell – Sertoli cell junction signalling pathway ENSG00000125755 ENSG00000070831 ENSG00000105926 ENSG00000087053 ENSG00000175899 ENSG00000143375 PMC7001271__F1 GPI biosynthesis pathway ENSG00000069943 ENSG00000135845 ENSG00000100564 ENSG00000197563 ENSG00000185808 ENSG00000255072 ENSG00000197121 ENSG00000165282 ENSG00000275600 ENSG00000142892 ENSG00000143315 ENSG00000161395 ENSG00000163964 ENSG00000108474 ENSG00000060642 ENSG00000101464 ENSG00000154889 ENSG00000124155 ENSG00000148985 ENSG00000197858 ENSG00000136908 PMC10527779__F3 Biochemical and Molecular Pathways in Neurodegenerative Diseases: An Integrated View ENSG00000147955 ENSG00000158828 ENSG00000073921 PMC6073722__F3 APC activity is decreased under nutrient conditions, and increased when nutrients are limiting ENSG00000145604 ENSG00000094880 ENSG00000134982 ENSG00000004897 ENSG00000099804 ENSG00000283100 PMC8969394__F1 Biosynthetic pathways of triterpenoids and strategies to improve their Biosynthetic Efficiency ENSG00000110921 ENSG00000197429 ENSG00000167508 PMC8619966__F1 Hedgehog Pathway Inhibitors against Tumor Microenvironment ENSG00000150782 ENSG00000151882 ENSG00000113520 ENSG00000128602 PMC4588730__F2 Functions of FGF19 and the corresponding mechanisms ENSG00000160867 ENSG00000077782 PMC3408431__F8 RhoA GTPase Switch Controls Cx43-Hemichannel Activity through the Contractile System ENSG00000163914 PMC6111862__F6 Model of ADAM‐17/EGFR signalling axis activation induced by deoxycholic acid in intestinal carcinogenesis ENSG00000109321 ENSG00000146648 PMC4053266__F3 Integrative pathway analysis ENSG00000261371 ENSG00000135903 ENSG00000080166 ENSG00000171791 ENSG00000162692 ENSG00000100146 ENSG00000076662 ENSG00000135605 ENSG00000121966 PMC5473031__F6 Gestational exposure to sidestream (secondhand) cigarette smoke promotes transgenerational epigenetic transmission of exacerbated allergic asthma and bronchopulmonary dysplasia ENSG00000020633 ENSG00000171791 PMC4309199__F2 Toll-like receptors and IL-1 receptor family signaling pathways ENSG00000187554 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC2576557__F10 Schematic diagram showing the pathway involved in high glucose- and high insulin-induced extracellular matrix protein synthesis mediated by GSK3B and eIF2BE ENSG00000198793 ENSG00000167658 PMC11355432__F7 Proposed model for the protective mechanism of CPE against CKD-induced HAS ENSG00000130234 ENSG00000105516 ENSG00000173599 PMC5615778__F2 Working model for sensing of glucose availability by AMPK and its potential interactions with the mTORC1 signalling pathway at the lysosome PMC8276045__F2 T Cell Specificity: A Great Challenge in Chagas Disease ENSG00000224320 ENSG00000134982 PMC3807489__F8 Proposed metabolic models for syntrophic growth of D ENSG00000127948 PMC2671566__F7 Wnt signals organize synaptic prepattern and axon guidance through the zebrafish unplugged/MuSK receptor ENSG00000213658 ENSG00000134569 ENSG00000030304 PMC3044050__F6 Spry2 and Spry2Y55F function in the context of EC MAPK signaling ENSG00000136158 ENSG00000115904 PMC4100437__F1 Hypothetical model of chemoresistance in human ovarian cancer cells ENSG00000135446 ENSG00000105810 ENSG00000026103 PMC6103457__F1 Cilia and intraflagellar transport ENSG00000118096 ENSG00000101052 ENSG00000100360 ENSG00000128581 ENSG00000068885 ENSG00000119650 ENSG00000114446 ENSG00000081870 ENSG00000138002 ENSG00000109083 ENSG00000187535 ENSG00000096872 ENSG00000105948 ENSG00000122970 PMC7869012__F6 Bioinformatics analysis of sevoflurane altered lncRNA-related pathways based on the dysregulated lncRNA co-expressed dysregulated mRNAs using ingenuity pathway analysis (IPA) software ENSG00000138449 ENSG00000138166 ENSG00000164761 ENSG00000119508 ENSG00000168356 ENSG00000177606 ENSG00000271303 ENSG00000131095 ENSG00000113532 ENSG00000125910 ENSG00000139200 ENSG00000136872 PMC8416371__F10 Based on Network Pharmacology to Explore the Potential Bioactive Compounds and Mechanisms of Zuojin Pill for the Treatment of Ulcerative Colitis ENSG00000148798 ENSG00000073910 ENSG00000174611 PMC3820656__F1 Scheme of the endothelial angiopoietin (Angpt)/Tie2 system highlighting fundamental signalling pathways ENSG00000163914 ENSG00000091879 ENSG00000154188 PMC7690450__F2 Curcumin, as a multitarget compound, induces apoptosis and cell cycle arrest in neuroblastoma (NB) cells through the modulation of PTEN–Akt, NFKB, and p53 signaling; mitochondrial dysfunction; and caspase activation ENSG00000002330 ENSG00000026103 PMC5693401__F3 Signaling pathway network model: Panel (a) presents the biological network describing the mTOR pathway (based on Fig ENSG00000198793 ENSG00000146648 PMC7412400__F7 Mechanistic map depicting the potential role of the HDAC1/LSD1/SESN2 pathway in VC in CRF ENSG00000198793 ENSG00000285069 ENSG00000163517 PMC8608878__F6 Schematic presentation of the circKDM4C-regulated pathway in BCa cells ENSG00000170558 ENSG00000107077 PMC8576090__F3 Bioprospecting of microalgae metabolites against cytokine storm syndrome during COVID-19 ENSG00000130234 ENSG00000172936 PMC5117516__F1 Viral sensing pathways that trigger host immune responses ENSG00000162711 ENSG00000213928 ENSG00000167207 ENSG00000276561 ENSG00000150782 ENSG00000183735 ENSG00000088888 ENSG00000105397 ENSG00000115415 ENSG00000172936 ENSG00000131323 ENSG00000175104 ENSG00000184216 PMC3157296__F8 Cell Autonomous Role of PTEN in Regulating Castration-Resistant Prostate Cancer Growth ENSG00000198793 ENSG00000177606 PMC10648981__F3 Jasmonates in coordinating secondary with primary metabolism ENSG00000197429 PMC11674460__F2 The molecular mechanism underlying the pleiotropic anticancer activity of As2O3 against GBM cells ENSG00000149311 ENSG00000175054 ENSG00000148400 ENSG00000100219 PMC6348685__F4 Putative genes and their expression patterns in the biosynthetic pathway of astaxanthin in H ENSG00000160752 ENSG00000117682 PMC11674460__F6 The molecular mechanism underlying the pleiotropic anticancer activity of tetrandrine against GBM cells and GSCs ENSG00000132646 ENSG00000146648 PMC6062504__F6 DLX1/DLX2 may influence MAPT via WNT or GABA signaling pathway ENSG00000111249 ENSG00000162624 ENSG00000186297 ENSG00000125084 PMC7175771__F1 Autophagy pathway ENSG00000177169 ENSG00000152348 ENSG00000123395 ENSG00000198793 ENSG00000144848 ENSG00000155792 ENSG00000145782 ENSG00000057663 PMC3169508__F3 Pathway interactions and detailed network visualization for the interactions with three apoptosis related pathways for the comparison between HF and LF diet at t = 0 ENSG00000162889 ENSG00000027075 ENSG00000168925 ENSG00000101367 ENSG00000067606 ENSG00000095015 ENSG00000115904 ENSG00000213341 ENSG00000142731 ENSG00000184216 ENSG00000166037 ENSG00000026103 PMC7737552__F1 Huaier induces apoptosis by upregulating p53 expression ENSG00000147649 ENSG00000198793 ENSG00000168036 PMC11987792__F3 Exosome-mediated DOX resistance in BC ENSG00000123091 ENSG00000148400 PMC3169508__F2 An indirect interaction between the Axon Guidance and Insulin Signaling pathways in the network for the comparison between HF and LF diet at t = 0 ENSG00000182511 ENSG00000070831 ENSG00000150907 PMC8545927__F2 Elucidate multidimensionality of type 1 diabetes mellitus heterogeneity by multifaceted information ENSG00000049323 ENSG00000278373 ENSG00000180772 ENSG00000143839 ENSG00000035928 ENSG00000049768 ENSG00000102010 ENSG00000110801 ENSG00000089159 ENSG00000065613 ENSG00000111726 ENSG00000084734 ENSG00000276051 ENSG00000277263 ENSG00000204520 ENSG00000100448 ENSG00000145384 ENSG00000143842 ENSG00000232629 ENSG00000237693 ENSG00000113441 ENSG00000111537 ENSG00000164691 ENSG00000160224 ENSG00000133124 PMC8759629__F1 MICROGLIA AS THERAPEUTIC TARGETS AFTER NEUROLOGICAL INJURY: Strategy for Cell Therapy PMC9046545__F10 Signaling Pathway and Small-Molecule Drug Discovery of FGFR: A Comprehensive Review ENSG00000066468 ENSG00000077782 ENSG00000010671 PMC11987792__F5 Exosome-mediated platinum drug resistance in breast cancer ENSG00000162711 ENSG00000185515 ENSG00000129195 ENSG00000184207 PMC6589740__F1 Diagram of the proteins and precursor/product sugars involved with guanosine diphosphate-fucose synthesis, Golgi transport and attachment of core fucose to N-linked glycoproteins ENSG00000254685 ENSG00000112699 PMC7737552__F2 Huaier inhibits cell proliferation and metastasis by upregulating DARC and downregulating its ligands ENSG00000168283 ENSG00000170558 PMC7895513__F7 Regulatory effects of PCSK9 on endothelial cell pyroptosis by increasing ROS production via the inhibition of UQCRC1 ENSG00000278718 ENSG00000162711 ENSG00000125538 ENSG00000010256 ENSG00000169174 PMC4669196__F3 Proteomics Perspective on Viral DNA Sensors in Host Defense and Viral Immune Evasion Mechanisms ENSG00000239732 ENSG00000164430 ENSG00000088888 ENSG00000163568 ENSG00000125538 ENSG00000163565 ENSG00000174953 ENSG00000172936 PMC9585259__F2 Changes in the urinary proteome before and after quadrivalent influenza vaccine and COVID-19 vaccination ENSG00000151657 ENSG00000169896 ENSG00000228278 ENSG00000070831 ENSG00000110799 ENSG00000110244 ENSG00000078369 ENSG00000138798 ENSG00000120885 ENSG00000055955 ENSG00000163815 ENSG00000274619 ENSG00000180447 ENSG00000150991 ENSG00000063660 ENSG00000145192 ENSG00000130402 PMC9403860__F1 How the crosstalk between innate immune sensors and metabolic pathways affect the outcome of Brucella abortus infection? ENSG00000163568 ENSG00000125538 ENSG00000198793 ENSG00000172936 PMC5175149__F7 Infergen Stimulated Macrophages Restrict Mycobacterium tuberculosis Growth by Autophagy and Release of Nitric Oxide ENSG00000105397 ENSG00000168610 ENSG00000142166 PMC11242587__F1 Association of type 2 diabetes mellitus with cancer, for example, pancreatic cancer ENSG00000171105 ENSG00000198793 ENSG00000168610 PMC10507626__F2 Molecular mechanism of inducing cognitive impairment in OSA patients through intermittent hypoxia (IH) ENSG00000162711 ENSG00000172936 PMC5268776__F12 Differential Feedback Regulation of Δ4-3-Oxosteroid 5Beta-Reductase Expression by Bile Acids ENSG00000090402 ENSG00000167910 ENSG00000180432 ENSG00000122787 PMC12100627__F9 Mechanism by which rSPD promotes in vitro replication of IBRV ENSG00000213928 ENSG00000143546 ENSG00000187608 ENSG00000157601 ENSG00000185745 ENSG00000239732 ENSG00000134321 ENSG00000105397 ENSG00000115415 ENSG00000125538 ENSG00000134070 ENSG00000136869 ENSG00000172936 ENSG00000175104 ENSG00000184216 PMC9496435__F3 Targeted genes in the mitogen‐activated protein kinase pathway (MAPK) ENSG00000111837 ENSG00000138606 ENSG00000102977 PMC7320879__F1 Toll-Like Receptors 2 and 4 in the Pathogenesis of Chronic Obstructive Pulmonary Disease ENSG00000136869 ENSG00000049768 PMC3173146__F8 Summary and working model ENSG00000135899 ENSG00000291971 ENSG00000146648 PMC7222183__F1 Main mechanisms in ferroptosis ENSG00000161905 ENSG00000196839 ENSG00000167468 ENSG00000111684 PMC8597024__F6 Identification of miR-499a-5p as a Potential Novel Biomarker for Risk Stratification in Endometrial Cancer ENSG00000134982 ENSG00000168036 PMC4404917__F1 Synthesis of EPA, DPA and DHA from ALA ENSG00000134824 ENSG00000149485 ENSG00000133835 ENSG00000161533 ENSG00000066322 ENSG00000197977 PMC12000086__F5 Synthesis pathways of 16 esters and alcohols ENSG00000197386 ENSG00000102977 PMC7222183__F3 Charcot-Marie-Tooth disease (CMT) pathways related to oxidative stress ENSG00000116688 ENSG00000104381 ENSG00000152137 PMC5915042__F1 Scheme describing the mechanism of lethal autophagy induced by DDA ENSG00000112561 PMC5808733__F1G Signal transducer and activator of transcription 2 deficiency is a novel disorder of mitochondrial fission ENSG00000213928 ENSG00000105397 ENSG00000115415 ENSG00000142166 PMC3340193__F8 Scheme to explain the increased production of HA in fro/fro (NSMase2−/−) mouse fibroblasts ENSG00000170961 ENSG00000198793 PMC5640978__F4 Pulmonary transcriptomic responses indicate a dual role of inflammation in pneumonia development and viral clearance during 2009 pandemic influenza infection ENSG00000108691 ENSG00000277943 PMC7311766__F2 DAMP/PAMP PPR pathway manipulation ENSG00000162711 ENSG00000172005 ENSG00000172936 ENSG00000125347 PMC6858840__F1 NAD+ biosynthetic and degradative enzymes ENSG00000105835 ENSG00000123572 ENSG00000278488 PMC2922498__F2 Schematic for DSB repair by HR and NHEJ pathways ENSG00000012048 ENSG00000083093 ENSG00000108384 ENSG00000130997 ENSG00000051180 PMC7592369__F4 Role of HIFA on fatty acids metabolism during cancer progression via epigenetic regulation ENSG00000062485 ENSG00000026103 PMC7592369__F1 Canonical and non-canonical regulation of HIF signaling ENSG00000198793 PMC6282138__F6 Proposed mechanisms of lipoprotein uptake and Fluocinolone acetonide effects on inflammation and lipid accumulation in THP-1 derived foam cells ENSG00000135218 ENSG00000288269 ENSG00000145321 PMC10985004__F5 Construction of signaling pathway between DEPs ENSG00000160789 ENSG00000105329 ENSG00000179091 ENSG00000198793 ENSG00000120437 ENSG00000070669 ENSG00000132170 ENSG00000108839 ENSG00000115415 ENSG00000205186 ENSG00000167468 ENSG00000080371 ENSG00000163879 ENSG00000189403 ENSG00000172426 ENSG00000284862 ENSG00000095794 PMC8472822__F1 Ferroptosis Mechanisms Involved in Hippocampal-Related Diseases ENSG00000196839 ENSG00000167468 ENSG00000197429 ENSG00000111684 ENSG00000115107 PMC8055737__F1 ESCAPE-NA1 Trial Brings Hope of Neuroprotective Drugs for Acute Ischemic Stroke: Highlights of the Phase 3 Clinical Trial on Nerinetide ENSG00000122194 PMC10379230__F5 Isoflurane Anesthesia’s Impact on Gene Expression Patterns of Rat Brains in an Ischemic Stroke Model ENSG00000196502 ENSG00000167941 ENSG00000122877 ENSG00000153201 ENSG00000163428 ENSG00000177888 PMC9072078__F7 Antineuroinflammatory Effect of Amburana cearensis and Its Molecules Coumarin and Amburoside A by Inhibiting the MAPK Signaling Pathway in LPS-Activated BV-2 Microglial Cells ENSG00000172936 ENSG00000175104 PMC5654406__F1 Sequence Evidence for the Presence of Two Tetrapyrrole Pathways in Euglena gracilis ENSG00000066926 ENSG00000080819 ENSG00000126088 ENSG00000188690 PMC2519541__F2 Integration of the AinS-AinR and LuxI-LuxR quorum sensory pathways ENSG00000159479 ENSG00000039537 PMC4362662__F7 A hypothetical illustration for the mechanism of resveratrol on the EMT of colorectal cancer PMC10728906__F4 Inflammatory activation of astrocytes and microglia by Alpha-Syn and phenotypic switching between astrocytes and microglia ENSG00000162711 ENSG00000198793 ENSG00000172936 PMC6803543__F3 Ras signaling pathway shown as an interacting network ENSG00000291603 ENSG00000070831 ENSG00000155903 ENSG00000099942 ENSG00000107175 ENSG00000160691 ENSG00000128272 ENSG00000213658 ENSG00000148082 ENSG00000135446 ENSG00000129946 ENSG00000010810 ENSG00000186716 ENSG00000163914 ENSG00000280477 ENSG00000144566 ENSG00000105810 PMC4530548__F1 Antiviral Defense Mechanisms in Honey Bees ENSG00000162924 ENSG00000166278 ENSG00000168040 ENSG00000144406 ENSG00000123908 PMC7460696__F1 Lysophosphatidate (LPA) signaling pathway ENSG00000163914 ENSG00000198670 PMC9614042__F10 LXR agonist inhibits inflammation through regulating MyD88 mRNA alternative splicing ENSG00000099995 ENSG00000172936 ENSG00000136869 PMC6961113__F1 B-vitamins, one carbon metabolism and related pathways ENSG00000284320 ENSG00000110395 ENSG00000124275 ENSG00000116761 ENSG00000116984 PMC3905285__F4 Possible pathways for lipoic acid attachment to mitochondrial Alpha-ketodehydrogenase apoenzymes ENSG00000121897 ENSG00000144182 ENSG00000175536 ENSG00000169599 PMC5968387__F8 Signaling pathways that are postulated to upregulate the expression of A20 and then inhibit inflammatory mediators in macrophages induced by M protein following GAS infection ENSG00000125538 ENSG00000172936 ENSG00000175104 PMC6185797__F1 GSK-3 regulated signaling pathways and splicing factor phosphorylation ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC6803282__F3 Mechanistic network analysis predicted by Ingenuity Pathway Analysis ENSG00000039537 ENSG00000107562 ENSG00000168036 ENSG00000091879 ENSG00000104368 ENSG00000072571 ENSG00000066468 ENSG00000118785 ENSG00000157227 ENSG00000164400 ENSG00000169429 ENSG00000100219 ENSG00000100985 PMC9524788__F1 CGAS-STING Pathway - Implications for Systemic Lupus Erythematosus ENSG00000183735 ENSG00000164430 ENSG00000173638 PMC11760447__F1 Comprehensive Overview of Ketone Bodies in Cancer Metabolism: Mechanisms and Application ENSG00000083720 ENSG00000075239 ENSG00000062485 ENSG00000117305 PMC11847347__F6 Cancer-secreted exosomal miR-1825 induces angiogenesis to promote colorectal cancer metastasis ENSG00000153487 PMC12060536__F10 Dual-responsive nanoparticles targeting ACE-II senescence for therapeutic mitigation of acute lung injury ENSG00000161634 ENSG00000169136 ENSG00000214285 ENSG00000100985 ENSG00000196365 ENSG00000125656 ENSG00000096717 ENSG00000124762 ENSG00000130513 PMC7692384__F10 Neurofibromin regulation of the growth factor-controlled Ras/PI3K signaling pathway ENSG00000198793 ENSG00000196712 PMC6021760__F5 Comparison of Quantitative Mass Spectrometry Platforms for Monitoring Kinase ATP Probe Uptake in Lung Cancer ENSG00000149311 ENSG00000140992 ENSG00000175054 ENSG00000177169 ENSG00000074590 ENSG00000117650 ENSG00000135446 ENSG00000198793 ENSG00000087586 ENSG00000166851 ENSG00000184304 PMC3431075__F1 NFKB members and NFKB signaling ENSG00000104856 ENSG00000186716 ENSG00000173039 PMC8934560__F3 Nourishing Better Vision: The ARVO 2021 Mildred Weisenfeld Award Lecture ENSG00000118402 ENSG00000119915 ENSG00000066322 ENSG00000197977 PMC5187800__F8 Schematic representation of metformin roles in TGFB1-induced epithelial-to-mesenchymal transition in cervical carcinoma cells ENSG00000198793 ENSG00000168610 PMC3705591__F2 Common signaling pathway for Toll/IL-1R (TIR) family members ENSG00000137033 ENSG00000134070 ENSG00000172936 ENSG00000175104 PMC8880046__F2 Adaptive Immune Responses, Immune Escape and Immune-Mediated Pathogenesis during HDV Infection ENSG00000168610 PMC9379395__F8 Nitroxoline suppresses metastasis in bladder cancer via EGR1/circNDRG1/miR-520h/smad7/EMT signaling pathway PMC9157490__F3 Prospective Medicinal Plants and Their Phytochemicals Shielding Autoimmune and Cancer Patients Against the SARS-CoV-2 Pandemic: A Special Focus on Matcha ENSG00000136869 PMC8436617__F3 N6-Methyladenosine in Cancer Immunotherapy: An Undervalued Therapeutic Target ENSG00000145388 ENSG00000150455 ENSG00000168610 ENSG00000165819 PMC8950598__F1 Signaling Pathway of TNF Receptors: Linking Animal Models of Renal Disease to Human CKD ENSG00000105664 ENSG00000102871 ENSG00000056558 ENSG00000157625 ENSG00000162924 ENSG00000166278 ENSG00000168040 ENSG00000168404 ENSG00000127191 ENSG00000285379 PMC4013670__F6 Schematic describing the proposed anti-inflammatory response resulting from resveratrol treatment and its effects on TLR4 following stimulation of chondrocytes with IL-1B ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000175104 PMC4480196__F1 MTOR-mediated T cell activation and lineage specification ENSG00000049768 PMC6311899__F3 Result of newborn mouse lens epithelial cell ENSG00000067141 ENSG00000281324 ENSG00000162337 ENSG00000173482 ENSG00000183762 ENSG00000157240 ENSG00000106571 ENSG00000163251 ENSG00000074181 ENSG00000075275 ENSG00000113361 ENSG00000115353 ENSG00000177283 ENSG00000077782 ENSG00000155760 ENSG00000107779 ENSG00000087095 ENSG00000138795 ENSG00000087903 ENSG00000213341 ENSG00000173546 ENSG00000129173 ENSG00000164742 ENSG00000115884 ENSG00000063660 ENSG00000213694 ENSG00000124440 ENSG00000104856 ENSG00000291971 ENSG00000181104 ENSG00000198793 ENSG00000170558 ENSG00000150093 ENSG00000080298 ENSG00000178764 ENSG00000175832 ENSG00000118515 ENSG00000179399 ENSG00000125266 ENSG00000281178 ENSG00000171105 ENSG00000169439 ENSG00000174804 ENSG00000043355 ENSG00000066468 ENSG00000154856 ENSG00000164050 ENSG00000104290 ENSG00000134853 ENSG00000076356 ENSG00000115232 PMC4480196__F2 Pharmacologically targetable regulatory checkpoints of the mTOR pathway PMC6621796__F11 Schematic drawing to illustrate JAK-STAT signaling pathway ENSG00000213928 ENSG00000131095 PMC7759999__F1 Opsonized epithelial apoptotic particles and ICs containing nuclear autoantigens bind to plasmacytoid DCs (pDCs) and RF B cells via TLRs and Fc receptors, respectively ENSG00000186716 ENSG00000145321 PMC3464089__F2 Aberrant activation of the MAPK signaling pathway in papillary thyroid tumor cells ENSG00000157764 PMC7497849__F3 CCL5-VEGF-A signaling pathway in BEV treatment ENSG00000112715 PMC11921692__F4 USPs and p53 signaling pathway ENSG00000124422 ENSG00000102226 ENSG00000055483 ENSG00000083799 PMC11921692__F3 USPs and Nrf2 signaling pathway ENSG00000135655 ENSG00000291527 ENSG00000102226 ENSG00000100387 ENSG00000155313 ENSG00000079999 PMC9240190__F6 Signaling Pathways Related to Oxidative Stress in Diabetic Cardiomyopathy ENSG00000005059 ENSG00000156026 ENSG00000198626 PMC11921692__F2 USPs and TGFB signaling pathway ENSG00000135655 ENSG00000102226 ENSG00000198742 ENSG00000083799 ENSG00000175104 ENSG00000134588 ENSG00000076604 PMC9240190__F5 Signaling Pathways Related to Oxidative Stress in Diabetic Cardiomyopathy ENSG00000163914 ENSG00000137845 PMC11921692__F1 USPs and NFKB signaling pathway ENSG00000104856 ENSG00000135655 ENSG00000137275 ENSG00000102871 ENSG00000172046 ENSG00000155313 ENSG00000127191 ENSG00000184979 ENSG00000102226 ENSG00000172936 ENSG00000131323 ENSG00000083799 ENSG00000175104 ENSG00000184216 PMC9240190__F4 Signaling Pathways Related to Oxidative Stress in Diabetic Cardiomyopathy ENSG00000162711 ENSG00000178573 ENSG00000172936 ENSG00000136869 ENSG00000175104 ENSG00000079999 PMC4798945__F7 A model of the tumor suppressive functions of TGM2 in HMECTERT/ST/ER-RasV12 cells ENSG00000284099 ENSG00000145782 ENSG00000124762 ENSG00000057663 PMC9240190__F3 Signaling Pathways Related to Oxidative Stress in Diabetic Cardiomyopathy ENSG00000177169 ENSG00000135218 ENSG00000142082 PMC6266917__F3 Systemic effects of increased adiposity on EC progression ENSG00000125538 ENSG00000128342 ENSG00000154188 PMC9240190__F2 Signaling Pathways Related to Oxidative Stress in Diabetic Cardiomyopathy ENSG00000169047 PMC6266917__F2 Contributions of activated/recruited stromal cells in endometrial cancer (EC) progression ENSG00000019991 ENSG00000125538 ENSG00000213853 ENSG00000121966 PMC7773816__F3 Effect of amino acids and their derivatives on T cell signaling ENSG00000291603 ENSG00000128272 ENSG00000213658 ENSG00000136997 PMC10907749__F2 Antagonizing the host immune response by T. gondii ENSG00000115415 ENSG00000168610 PMC7773816__F1 Role of amino acids and amino-acid catabolizing enzymes in T-cell activation ENSG00000145321 ENSG00000105639 ENSG00000106546 PMC10907749__F1 Host immune responses to T. gondii infection ENSG00000239732 ENSG00000140968 ENSG00000172936 ENSG00000136869 ENSG00000110057 PMC10907749__F4 T. gondii antigen alters the signaling pathway of the host cell ENSG00000120833 ENSG00000162711 ENSG00000111537 ENSG00000136869 ENSG00000118520 ENSG00000168610 PMC3887453__F2 Mitochondrial Redox Signaling: Interaction of Mitochondrial Reactive Oxygen Species with Other Sources of Oxidative Stress ENSG00000086991 ENSG00000213999 PMC8123284__F3 Alteration of Iron Concentration in Alzheimer’s Disease as a Possible Diagnostic Biomarker Unveiling Ferroptosis ENSG00000168003 ENSG00000151012 ENSG00000167468 PMC8123284__F2 Alteration of Iron Concentration in Alzheimer’s Disease as a Possible Diagnostic Biomarker Unveiling Ferroptosis ENSG00000182511 PMC10854812__F10 Selected agents targeting the Fyn/CD133/PI3K/Akt/mTOR pathway ENSG00000010810 ENSG00000198793 PMC4826221__F9 Galiellalactone induces cell cycle arrest and apoptosis through the ATM/ATR pathway in prostate cancer cells ENSG00000149311 ENSG00000175054 PMC6780840__F3 Intracellular peptidoglycan (PGN) is detected by intracellular receptors and activates the NFKB signaling pathway in Drosophila melanogaster and human enterocytes ENSG00000162924 ENSG00000127191 PMC7299241__F3 Actions of IGF-1 in the Growth Plate and its Role in Postnatal Bone Elongation ENSG00000002330 ENSG00000198793 PMC9589007__F5 Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues ENSG00000110921 ENSG00000112972 ENSG00000172893 ENSG00000113161 ENSG00000120437 ENSG00000167508 ENSG00000052802 ENSG00000160752 ENSG00000001630 ENSG00000116133 ENSG00000152904 ENSG00000143815 ENSG00000141086 ENSG00000149809 ENSG00000162438 ENSG00000104549 PMC7253212__F5 Interaction of FXR signaling and pathways relevant for zileuton-induced hepatotoxicity ENSG00000135218 ENSG00000171234 ENSG00000135100 ENSG00000005882 ENSG00000107798 ENSG00000275190 ENSG00000197408 ENSG00000197375 ENSG00000065559 ENSG00000176153 ENSG00000118777 ENSG00000132170 ENSG00000130304 ENSG00000136997 ENSG00000161533 ENSG00000100979 ENSG00000115361 ENSG00000073734 ENSG00000140284 ENSG00000136689 ENSG00000023839 ENSG00000262243 ENSG00000186198 ENSG00000100372 PMC9589007__F4 Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues ENSG00000151376 ENSG00000073578 ENSG00000063854 ENSG00000005882 ENSG00000087299 ENSG00000163541 ENSG00000105953 ENSG00000112992 ENSG00000131828 ENSG00000101365 ENSG00000143252 ENSG00000065833 ENSG00000100412 ENSG00000162438 ENSG00000110435 ENSG00000146701 ENSG00000082212 ENSG00000091140 ENSG00000141526 ENSG00000060762 ENSG00000062485 PMC5217037__F7 miR-130b, an onco-miRNA in bladder cancer, is directly regulated by NFKB and sustains NFKB activation by decreasing Cylindromatosis expression ENSG00000083799 ENSG00000127191 PMC7810939__F6 GSEA analysis and gene‐pathway regulatory network in the liver ENSG00000101670 ENSG00000140992 ENSG00000115904 ENSG00000169710 ENSG00000105647 ENSG00000141564 ENSG00000100485 ENSG00000105607 ENSG00000072210 ENSG00000136267 ENSG00000163558 ENSG00000150907 ENSG00000026652 ENSG00000100504 ENSG00000186281 ENSG00000113790 ENSG00000104365 ENSG00000157764 ENSG00000138029 ENSG00000172955 ENSG00000143933 ENSG00000058866 ENSG00000143387 ENSG00000106617 ENSG00000161533 ENSG00000102893 ENSG00000122971 ENSG00000159399 PMC9589007__F7 Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues ENSG00000244414 ENSG00000160339 ENSG00000203710 ENSG00000110651 ENSG00000244731 ENSG00000120885 ENSG00000182326 ENSG00000184500 ENSG00000180210 ENSG00000274619 ENSG00000173369 ENSG00000116785 ENSG00000117335 ENSG00000196352 ENSG00000165471 ENSG00000292003 ENSG00000039537 ENSG00000009724 ENSG00000113600 ENSG00000291559 ENSG00000123843 ENSG00000120054 ENSG00000000971 ENSG00000166278 ENSG00000176919 ENSG00000159189 ENSG00000157131 ENSG00000173372 ENSG00000178772 ENSG00000141086 ENSG00000134365 ENSG00000288512 ENSG00000292002 ENSG00000123838 ENSG00000080618 PMC3235520__F1 Proposed model of the type I interferon induction by HIV-1 and HIV-1-infected cells ENSG00000239732 ENSG00000172936 ENSG00000121966 PMC9589007__F6 Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues ENSG00000101000 ENSG00000110799 ENSG00000181104 ENSG00000115718 ENSG00000122194 ENSG00000178726 ENSG00000163815 ENSG00000185010 ENSG00000104368 ENSG00000137801 ENSG00000184500 ENSG00000180210 ENSG00000126218 ENSG00000101981 ENSG00000117525 ENSG00000011422 ENSG00000168398 ENSG00000171560 ENSG00000164220 ENSG00000113889 ENSG00000003436 ENSG00000197632 ENSG00000163736 ENSG00000088926 ENSG00000113905 ENSG00000117601 ENSG00000141086 ENSG00000057593 ENSG00000175899 ENSG00000080618 ENSG00000198734 ENSG00000100739 ENSG00000276838 PMC4385831__F6 Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNFA and ROS production ENSG00000104856 ENSG00000137275 ENSG00000102871 ENSG00000127191 ENSG00000285379 PMC5331050__F5 NOD-like receptor signaling pathway ENSG00000167207 ENSG00000125538 ENSG00000157625 ENSG00000106100 PMC5223597__F8 Proposed model for the role INPP5E plays at cilia ENSG00000205084 ENSG00000143147 ENSG00000123810 ENSG00000108641 ENSG00000011143 ENSG00000148384 ENSG00000128602 ENSG00000281857 PMC10989355__F4 Molecular signaling pathways affected by electrical stimulation (ES) of peripheral nerves PMC10989355__F2 Regulatory signaling pathways activating Schwann cells (SCs) response in peripheral nerve regeneration (PNR) ENSG00000242689 ENSG00000291971 ENSG00000100146 ENSG00000103335 PMC10989355__F1 Pivotal signaling cascades in peripheral nerve regeneration (PNR) ENSG00000198793 PMC5041313__F2 CB1 cannabinoid receptor signaling and regulation of neural stem/progenitor cell proliferation ENSG00000076864 ENSG00000291971 ENSG00000168610 PMC3712043__F1 Activation of the IRS signaling cascade pathways ENSG00000177169 ENSG00000169291 ENSG00000002330 ENSG00000083290 ENSG00000198793 ENSG00000164327 PMC5331050__F3 Toll-like receptor signaling pathway ENSG00000174125 ENSG00000183735 ENSG00000239732 ENSG00000187554 ENSG00000125538 ENSG00000172936 ENSG00000136869 ENSG00000131323 ENSG00000175104 ENSG00000164342 PMC6885362__F4 Whole Transcriptomic Analysis of Apigenin on TNFA Immuno-activated MDA-MB-231 Breast Cancer Cells ENSG00000163235 ENSG00000134982 ENSG00000158825 ENSG00000164399 PMC6548820__F10 The proposed mechanism for the indirect pathway of allorecognition in the T cell areas of the spleen and LNs ENSG00000173578 ENSG00000151914 PMC3000682__F7 Pro-inflammatory pathway induction by cAMP/PKA signaling in BSC-derived lesions ENSG00000125538 PMC6885362__F3 Whole Transcriptomic Analysis of Apigenin on TNFA Immuno-activated MDA-MB-231 Breast Cancer Cells ENSG00000144410 ENSG00000170458 ENSG00000168040 ENSG00000150455 ENSG00000175104 ENSG00000142224 ENSG00000135517 ENSG00000143387 PMC8786804__F5 Sex-Stratified Single-Cell RNA-Seq Analysis Identifies Sex-Specific and Cell Type-Specific Transcriptional Responses in Alzheimer’s Disease Across Two Brain Regions ENSG00000168259 ENSG00000284774 ENSG00000106004 ENSG00000118785 ENSG00000173917 ENSG00000163914 ENSG00000115221 ENSG00000150093 ENSG00000179915 PMC11734361__F3 Tumor-associated-mycobiome mechanisms involved in triggering oncogenesis and cancer development ENSG00000162711 ENSG00000187796 ENSG00000137033 ENSG00000168610 PMC4709785__F1 Metabolic regulation of the pluripotent epigenetic landscape ENSG00000147162 ENSG00000175567 PMC11734361__F4 Tumor-associated-mycobiome regulates the physiological and immune responses of cancer through different signaling pathways ENSG00000104812 ENSG00000159224 ENSG00000167207 ENSG00000187796 ENSG00000115415 ENSG00000159399 PMC6433964__F3 Repair pathways and signaling in response to DSB induction by IR ENSG00000149311 ENSG00000175054 ENSG00000051180 ENSG00000139618 PMC3397239__F2 Anaplasma phagocytophilum: deceptively simple or simply deceptive? ENSG00000067900 ENSG00000064012 ENSG00000164305 PMC8908320__F8 Novel Copper(II) Indenoisoquinoline Complex Inhibits Topoisomerase I, Induces G2 Phase Arrest, and Autophagy in Three Adenocarcinomas ENSG00000149311 ENSG00000175054 ENSG00000198793 PMC2234385__F10 Model of TLR ligand activation of Kupffer cell–NK cell cross talk in co-culture ENSG00000226275 ENSG00000172936 ENSG00000136869 ENSG00000164342 PMC8524136__F10 Smoothelin-Like Protein 1 Regulates Development and Metabolic Transformation of Skeletal Muscle in Hyperthyroidism ENSG00000169047 ENSG00000214872 PMC4166537__F4 CCR-14-0330R1: Concurrent Alterations in TERT, KDM6A, and the BRCA Pathway in Bladder Cancer ENSG00000145362 ENSG00000124102 ENSG00000156983 ENSG00000164796 ENSG00000142534 ENSG00000140807 ENSG00000149311 ENSG00000101972 ENSG00000060656 ENSG00000131018 ENSG00000107611 ENSG00000139687 ENSG00000146648 ENSG00000196367 ENSG00000124177 PMC8836812__F4 Unraveling the Signaling Secretome of Platelet-Rich Plasma: Towards a Better Understanding of Its Therapeutic Potential in Knee Osteoarthritis ENSG00000108702 ENSG00000157404 ENSG00000105329 ENSG00000111321 ENSG00000064300 ENSG00000115457 ENSG00000167779 ENSG00000138755 ENSG00000141753 ENSG00000146678 ENSG00000169429 ENSG00000113520 ENSG00000189403 ENSG00000164400 ENSG00000037280 ENSG00000104432 ENSG00000106178 ENSG00000130513 ENSG00000275718 ENSG00000164761 ENSG00000143125 ENSG00000277943 ENSG00000226275 ENSG00000108691 ENSG00000164136 ENSG00000146648 PMC8836812__F3 Unraveling the Signaling Secretome of Platelet-Rich Plasma: Towards a Better Understanding of Its Therapeutic Potential in Knee Osteoarthritis ENSG00000108702 ENSG00000019991 ENSG00000157404 ENSG00000165197 ENSG00000105329 ENSG00000138798 ENSG00000111321 ENSG00000168811 ENSG00000112715 ENSG00000064300 ENSG00000150782 ENSG00000049130 ENSG00000138755 ENSG00000169429 ENSG00000113520 ENSG00000164400 ENSG00000037280 ENSG00000104432 ENSG00000106178 ENSG00000182578 ENSG00000115008 ENSG00000164761 ENSG00000113070 ENSG00000108342 ENSG00000143125 ENSG00000277943 ENSG00000225950 ENSG00000197461 ENSG00000185652 ENSG00000226275 ENSG00000108691 ENSG00000111537 ENSG00000163235 ENSG00000140285 ENSG00000164136 ENSG00000184371 ENSG00000113302 ENSG00000112115 ENSG00000146648 PMC7644826__F2 Canonical WNT signaling ENSG00000281324 ENSG00000162337 ENSG00000134982 PMC5127148__F1 Expression of myogenes in longissimus dorsi muscle during prenatal development in commercial and local Piau pigs ENSG00000176401 ENSG00000104365 ENSG00000138795 ENSG00000122180 ENSG00000285438 ENSG00000169032 ENSG00000100888 ENSG00000166135 ENSG00000146374 PMC8470542__F10 Effects of Two Nrf2 Activators, Bardoxolone Methyl and Omaveloxolone, on Retinal Ganglion Cell Survival during Ischemic Optic Neuropathy ENSG00000181019 ENSG00000118520 PMC7019133__F1 Canonical Wnt/Beta-catenin pathway ENSG00000281324 ENSG00000162337 ENSG00000134982 ENSG00000168036 PMC7019133__F3 Role of sFRP2 in cardiovascular disease ENSG00000163251 PMC5129466__F1 Insulin receptor (IR) and insulin‐like growth factor 1 receptor (IGF1R) signalling pathway PMC5774495__F4 Osteoclast differentiation signaling pathway ENSG00000095585 ENSG00000213928 ENSG00000111537 ENSG00000083799 ENSG00000127191 ENSG00000143387 PMC5956974__F11 Function of the hub genes in the cell cycle signaling pathway visualized in the Kyoto Encyclopedia of Genes and Genomes (KEGG) map obtained by the Database for Annotation, Visualization and Integrated Discovery (DAVID) ENSG00000172680 ENSG00000132646 ENSG00000172005 PMC3797434__F7 IL-32-PAR2 axis is an innate immunity sensor providing alternative signaling for LPS-TRIF axis ENSG00000183735 ENSG00000172936 ENSG00000175104 ENSG00000276561 PMC7784358__F5 KEGG pathway enrichment analysis and pathway map for RA ENSG00000165983 ENSG00000152266 ENSG00000108691 ENSG00000163599 ENSG00000105656 ENSG00000115009 ENSG00000143387 PMC11663348__F1 Stimulation by oral pathogenic bacteria induce dysfunctional PDLFs ENSG00000162711 ENSG00000167207 ENSG00000105808 ENSG00000136869 ENSG00000130159 ENSG00000168404 ENSG00000110218 ENSG00000168610 ENSG00000285379 PMC5661640__F4 General overview of the process of cell death in SMA ENSG00000002330 ENSG00000198793 PMC5661640__F3 Schematic presentation of suggested pathways of PTEN involvement in neuronal survival ENSG00000002330 ENSG00000198793 ENSG00000026103 PMC3136563__F12 Working model for the role of USP4 in the negative regulation of TNFAlpha-induced TAK1 polyubiquitnation and NFKB activation ENSG00000135655 ENSG00000102226 ENSG00000102871 ENSG00000082512 ENSG00000173039 ENSG00000157625 ENSG00000162924 ENSG00000083799 ENSG00000127191 ENSG00000143258 PMC11580480__F8 Summary chart ENSG00000146648 PMC6629629__F3 Clinical update on head and neck cancer: molecular biology and ongoing challenges ENSG00000135446 ENSG00000198793 ENSG00000123374 ENSG00000105810 ENSG00000146648 PMC10382538__F7 Schematic model of the anti-inflammatory effects of IL4I1 on LPS induced-ALI ENSG00000027697 ENSG00000106546 PMC6629629__F2 Clinical update on head and neck cancer: molecular biology and ongoing challenges ENSG00000019991 ENSG00000198793 ENSG00000146648 PMC9682773__F4 Insight into the physiological and pathological roles of the aryl hydrocarbon receptor pathway in glucose homeostasis, insulin resistance, and diabetes development ENSG00000042832 ENSG00000106546 PMC8798411__F5 Comparison of whole exome sequencing in circulating tumor cells of primitive and metastatic nasopharyngeal carcinoma ENSG00000291656 ENSG00000111057 ENSG00000033327 ENSG00000081853 ENSG00000229676 ENSG00000125107 ENSG00000253846 ENSG00000185177 ENSG00000060237 ENSG00000291684 ENSG00000153201 ENSG00000291692 ENSG00000291654 ENSG00000018408 ENSG00000221923 ENSG00000170100 ENSG00000100162 ENSG00000070756 ENSG00000291983 ENSG00000157557 ENSG00000186716 ENSG00000152926 ENSG00000213523 PMC9682773__F3 Insight into the physiological and pathological roles of the aryl hydrocarbon receptor pathway in glucose homeostasis, insulin resistance, and diabetes development ENSG00000042832 ENSG00000106546 PMC9682773__F2 Insight into the physiological and pathological roles of the aryl hydrocarbon receptor pathway in glucose homeostasis, insulin resistance, and diabetes development ENSG00000140465 ENSG00000106546 PMC9601130__F1 Novel Approaches in Non-Melanoma Skin Cancers—A Focus on Hedgehog Pathway in Basal Cell Carcinoma (BCC) ENSG00000106571 ENSG00000166813 ENSG00000128602 PMC6347823__F7 A schematic model showing the effects of duodenal ghrelin on hepatic glucose fluxes and insulin signals ENSG00000171105 PMC3074487__F8 Migration of FGF7-stimulated epithelial cells and VEGF-A-stimulated HUVECs depends on EGFR transactivation by ADAM17 ENSG00000291971 ENSG00000113070 ENSG00000138798 ENSG00000146648 PMC9233299__F7 Beta-Cell Succinate Dehydrogenase Deficiency Triggers Metabolic Dysfunction and Insulinopenic Diabetes ENSG00000117118 ENSG00000124523 ENSG00000166278 PMC7760327__F1 Cellular copper homeostasis in hepatocytes (A) and fibroblasts (B) ENSG00000173992 ENSG00000138495 ENSG00000141086 ENSG00000123191 ENSG00000177556 ENSG00000133028 ENSG00000284194 ENSG00000062485 PMC9437524__F1 Neutrophil extracellular traps: New players in cancer research ENSG00000239732 ENSG00000109861 ENSG00000147419 ENSG00000189403 ENSG00000100985 PMC6541606__F7 Human mesenchymal stem cells promote tumor growth via MAPK pathway and metastasis by epithelial mesenchymal transition and integrin A5 in hepatocellular carcinoma PMC6433964__F2 Regulation of PD-L1 expression in response to DNA damage in cancer cells ENSG00000149311 ENSG00000175054 ENSG00000164430 PMC7002344__F10 Differential phosphorylation of MAPK pathways during response to cell wall damage ENSG00000070831 ENSG00000136425 ENSG00000006712 ENSG00000149489 ENSG00000166278 PMC12113985__F7 Novel Camel Milk-Derived Peptide LLPK Improves Glucose-Lipid Metabolism in db/db Mice via PPAR Signaling Pathway ENSG00000197635 ENSG00000161533 ENSG00000113790 PMC8130364__F1 Predictive biomarkers and potential drug combinations of epi-drugs in cancer therapy ENSG00000169554 ENSG00000157764 ENSG00000099810 PMC8740229__F2 Targeting TREM2 for Parkinson’s Disease: Where to Go? ENSG00000162711 ENSG00000136869 PMC3234798__F9 miR-26a pathway in the initiation of ASMC hypertrophy ENSG00000175215